Browse by Research Area

2024

The gut microbiome strongly mediates the impact of lifestyle combined variables on cardiometabolic phenotypes.
Adriouch, S., Belda, E., Swartz, T.D., Forslund, S., Le Roy, Ti., Prifti, E., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Andrikopoulos, P., Chechi, K., Puig-Castellví, F., Froguel, P., Holmes, B., Alili, R., Andreelli, F., Soula, H., Salem, J.E., Falony, G., Vieira-Silva, S., Galazzo, Gi., Raes, J., Bork, P., Stumvoll, M., Pedersen, O., Ehrlich, S.D., Dumas, M.E., Oppert, J.M., Dao, M.C., Zucker, J.D. and Clément, K.
medRxiv : 2024.01.12.24301195v2. 17 January 2024

Rigorous science demands support of transgender scientists.
Aghi, K., Anderson, B.M., Castellano, B.M., Cunningham, A., Delano, M., Dickinson, E.S., von Diezmann, L., Forslund-Startceva, S.K., Grijseels, D.M., Groh, S.S., Guthman, E.M., Jayasinghe, I., Johnston, J., Long, S., McLaughlin, J.F., McLaughlin, M., Miyagi, M., Rajaraman, B., Sancheznieto, F., Scheim, A.I., Sun, S.E.D., Titmuss, F.D., Walsh, R.J. and Weinberg, Z.Y.
Cell 187 (6): 1327-1334. 14 March 2024

Calibration-free parallel transmission of the cervical, thoracic, and lumbar spinal cord at 7T.
Aigner, C.S., Sánchez Alarcon, M.F., D'Astous, A., Alonso-Ortiz, E., Cohen-Adad, J. and Schmitter, S.
Magnetic Resonance in Medicine 92 (4): 1496-1510. October 2024

Donor-derived cell-free DNA monitoring for early diagnosis of antibody-mediated rejection after kidney transplantation: a randomized trial.
Akifova, A., Budde, K., Amann, K., Buettner-Herold, M., Choi, M., Oellerich, M., Beck, J., Bornemann-Kolatzki, K., Schütz, E., Bachmann, F., Halleck, F., von Hoerschelmann, E., Koch, N., Schrezenmeier, E., Seelow, E., Waiser, J., Zukunft, B., Eckardt, K.U., Halbritter, J., Kettritz, R., Del Moral, C.L., Lachmann, N., Stauch, D., Niemann, M., Schmidt, D., Halloran, P.F. and Osmanodja, B.
Nephrology Dialysis Transplantation 29 November 2024 (In Press)

Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, O., Sünkel, C., Blanc, E., Catar, R.A., Ashraf, M.I., Zhao, H., Wang, P., Rinschen, M.M., Fritsche-Guenther, R., Grahammer, F., Bachmann, S., Beule, D., Kirwan, J.A., Rajewsky, N., Huber, T.B., Gürgen, D. and Kusch, A.
Biology of Sex Differences 15 (1): 72. 15 September 2024

Cardiovascular multimodality imaging in women. A scientific statement of the European Association of Cardiovascular Imaging (EACVI) of the ESC.
Almeida, A.G., Grapsa, J., Gemelli, A., Bucciarelli-Ducci, C., Gerber, B., Ajmone-Marsan, N., Bernard, A., Donal, E., Dweck, M.R, Haugaa, K.H., Hristova, K., Maceira, A., Mandoli, G.E., Mulvagh, S., Morrone, D., Plonska-Gosciniak, E., Sade, L.E., Schivalkar, B., Schulz-Menger, J., Shaw, L., Sitges, M., von Kemp, B., Pinto, F.J., Edvardsen, T., Petersen, S.E. and Cosyns, B.
European Heart Journal - Cardiovascular Imaging 25 (4): e116-e136. April 2024

Poor decision making and sociability impairment following central serotonin reduction in inducible TPH2-knockdown rats.
Alonso, L., Peeva, P., Fernández-del Valle Alquicira, T., Erdelyi, N., Gil Nolskog, Á., Bader, M., Winter, Y., Alenina, N. and Rivalan, M.
International Journal of Molecular Sciences 25 (9): 5003. May 2024

Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors.
Amado Costa, L., Oliveira Amaral, L.B., Mourão, F.A.G., Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Hormones and Behavior 163 : 105551. 27 April 2024

A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on pulmonary circulation & right ventricular function.
Ameri, P., Mercurio, V., Pollesello, P., Anker, M.S., Backs, Jo., Bayes-Genis, A., Borlaug, B.A., Burkhoff, D., Caravita, S., Chan, S.Y., de Man, F., Giannakoulas, G., González, A., Guazzi, M., Hassoun, P.M., Hemnes, A.R., Maack, C., Madden, B., Melenovsky, V., Müller, O.J., Papp, Z., Pullamsetti, S.S., Rainer, P.P., Redfield, M.M., Rich, S., Schiattarella, G.G., Skaara, H., Stellos, K., Tedford, R.J., Thum, T., Vachiery, J.L., van der Meer, P., Van Linthout, S., Pruszczyk, P., Seferovic, P., Coats, A.J.S., Metra, M., Rosano, G., Rosenkranz, S. and Tocchetti, C.G.
European Journal of Heart Failure 26 (4): 707-729. April 2024

Segmental patterning of microbiota and immune cells in the murine intestinal tract.
Anandakumar, H., Rauch, A., Wimmer, M.I., Yarritu, A., Koch, G., McParland, V., Bartolomaeus, H. and Wilck, N.
Gut Microbes 16 (1): 2398126. 2024

Rapid MR elastography of the liver for subsecond stiffness sampling.
Anders, M., Meyer, T., Warmuth, C., Pfeuffer, J., Tzschaetzsch, H., Herthum, H., Shahryari, M., Degenhardt, K., Wieben, O., Schmitter, S., Schulz-Menger, J., Schaeffter, T., Braun, J. and Sack, I.
Magnetic Resonance in Medicine 91 (1): 312-324. January 2024

Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface.
Avery, E.G., Haag, L.M., McParland, V., Kedziora, S.M., Zigra, G.J., Valdes, D.S., Kirchner, M., Popp, O., Geisberger, S., Nonn, O., Karlsen, T.V., N'Diaye, G., Yarritu, A., Bartolomaeus, H., Bartolomaeus, T.U.P., Wimmer, M.I., Haase, N., Wilhelm, A., Grütz, G., Tenstad, O., Wilck, N., Forslund, S.K., Klopfleisch, R., Kühl, A.A., Atreya, R., Kempa, S., Mertins, P., Siegmund, B., Wiig, H. and Müller, D.N.
bioRxiv : 2024.01.11.574524. 11 January 2024

Identification and Mitigation of microbial contaminant reads from long-read metagenomic samples.
Ayala-Montano, S., Afolayan, A.O., Kociurzynski, R., Loeber, U. and Reuter, S.
bioRxiv : 2024.11.26.625374v1. 1 December 2024

ADAM19 cleaves the PTH receptor and associates with brachydactyly type E.
Aydin, A., Klenk, C., Nemec, K., Işbilir, Ali, Martin, L.M., Zauber, H., Rrustemi, T., Toka, H.R., Schuster, H., Gong, M., Stricker, S., Bock, A., Bähring, S., Selbach, M., Lohse, M.J. and Luft, F.C.
Life Science Alliance 7 (4): e202302400. April 2024

High-sensitivity cardiac troponin I enhances preeclampsia prediction beyond maternal factors and the sFlt-1/PlGF ratio.
Bacmeister, L., Goßling, A., Buellesbach, A., Birukov, A., Myers, J.E., Thomas, S.T., Lee, S., Andersen, M.S., Jorgensen, J.S., Diemert, A., Blois, S.M., Arck, P.C., Hecher, K., Herse, F., Blankenberg, S., Dechend, R., Westermann, D. and Zeller, T.
Circulation 149 (2): 95-106. 9 January 2024

Alternative renin-angiotensin system.
Bader, M., Muscha Steckelings, U., Alenina, N., Santos, R.A.S. and Ferrario, C.M.
Hypertension 81 (5): 964-976. May 2024

Baseline MRI examination in the NAKO health study - findings on feasibility, participation and dropout rates, comfort, and image quality.
Bamberg, F., Schlett, C.L., Caspers, S., Ringhof, S., Günther, M., Hirsch, J.G., Rüdebusch, J., Miklánková, P., Bittner, N., Jockwitz, C., Forsting, M., Hosten, N., Kaaks, R., Kauczor, H.U., Kroenke, T., Niendorf, T., Peters, A., Pischon, T., Stang, A., Berger, K. and Völzke, H.
Deutsches Arzteblatt International 121 (18): 587-593. 6 September 2024

Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) is reduced with preeclampsia and small for gestational aged fetuses.
Bartho, L.A., Walker, S.P., Cannon, P., Nguyen, T.V., Nguyen, A., Botha, S.M., Hannan, N.J., Tong, S. and Kaitu'u-Lino, T.J.
Placenta 156 : 10-13. October 2024

Gut-immune axis and cardiovascular risk in chronic kidney disease.
Behrens, F., Bartolomaeus, H., Wilck, N. and Holle, J.
Clinical Kidney Journal 17 (1): sfad303. January 2024

A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction.
Bender, R.H.F., O'Donnell, B.T., Shergill, B., Pham, B.Q., Tahmouresie, S., Sanchez, C.N., Juat, D.J., Hatch, M.M.S., Shirure, V.S., Wortham, M., Nguyen-Ngoc, K.V., Jun, Y., Gaetani, R., Christman, K.L., Teyton, L., George, S.C., Sander, M. and Hughes, C.C.W.
Biofabrication 16 (2): 025001. 11 January 2024

SoccHealth: a health status examination of former professional football (soccer) players within the German National Cohort.
Berger, K., Baurecht, H., Stein, M., Heise, J.K., Castell, S., Weisser, L., Schikowski, T., Oliver, K., Lieb, W., Micolajczyk, R., Kluttig, A., Schmitt, B., Stang, A., Pischon, T., Peters, A., Brenner, H., Leitzmann, M., Krist, L., Keil, T., Karch, A. and Meyer, T.
BMJ Open Sport & Exercise Medicine 10 (4): e002228. 1 October 2024

Association of adverse clinical outcomes with peri-infarct ischemia detected by stress cardiac magnetic imaging.
Bernhard, B., Ge, Y., Antiochos, P., Heydari, B., Islam, S., Sanchez Santiuste, N., Steel, K.E., Bingham, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Shanbhag, S.M., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Raman, S.V., Ferrari, V.A., Shah, D.J., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
Journal of the American College of Cardiology 84 (5): 417-429. 30 July 2024

Oral microbiota of patients with phenylketonuria: a nation-based cross-sectional study.
Bingöl, M., Cardilli, A., Bingöl, A.C., Löber, U., Bang, C., Franke, A., Bartzela, T., Beblo, S., Mönch, E., Stolz, S., Schaefer, A.S., Forslund, S.K. and Richter, G.M.
Journal of Clinical Periodontology 51 (8): 1081-1092. August 2024

Amplification of autoimmune organ damage by NKp46-activated ILC1.
Biniaris-Georgallis, S.I., Aschman, T., Stergioula, K., Schreiber, F., Jafari, V., Taranko, A., Karmalkar, T., Kasapi, A., Lenac Rovis, T., Jelencic, V., Bejarano, D.A., Fabry, L., Papacharalampous, M., Mattiola, I., Molgora, M., Hou, J., Hublitz, K.W., Heinrich, F., Guerra, G.M., Durek, P., Patone, G., Lindberg, E.L.H., Maatz, H., Hölsken, O., Krönke, G., Mortha, A., Voll, R.E., Clarke, A.J., Hauser, A.E., Colonna, M., Thurley, K., Schlitzer, A., Schneider, C., Stamatiades, E.G., Mashreghi, M.F., Jonjic, S., Hübner, N., Diefenbach, A., Kanda, M. and Triantafyllopoulou, A.
Nature 634 (8035): 952-960. 24 October 2024

Microbiome dynamics and functional composition in Coelopa frigida (Diptera, Coelopidae): insights into trophic specialization of kelp flies.
Bischof, P.S.P., Bartolomaeus, T.U.P., Löber, U. and Bleidorn, C.
Microbial Ecology 87 (1): 91. 3 July 2024

Endothelial overexpression of TGF-β-induced protein impairs venous thrombus resolution.
Bochenek, M.L., Saar, K., Nazari-Jahantigh, M., Gogiraju, R., Wiedenroth, C.B., Münzel, T., Mayer, E., Fink, L., Schober, A., Hübner, N., Guth, S., Konstantinides, S. and Schäfer, K.
JACC: Basic to Translational Science 9 (1): 100-116. January 2024

Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications.
Bode, D., Pronto, J.R.D., Schiattarella, G.G. and Voigt, N.
Nature Reviews Cardiology 21 (10): 682-700. October 2024

Dietary protein and blood pressure: an umbrella review of systematic reviews and evaluation of the evidence.
Boeing, H., Amini, A.M., Haardt, J., Schmidt, A., Bischoff-Ferrari, H.A., Buyken, A.E., Egert, S., Ellinger, S., Kroke, A., Lorkowski, S., Louis, S., Nimptsch, K., Schulze, M.B., Schutkowski, A., Schwingshackl, L., Siener, R., Zittermann, A., Watzl, B. and Stangl, G.I.
European Journal of Nutrition 63 (4): 1041-1058. June 2024

Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N., Bader, M., Willnow, T.E., Wiedenmann, B. and Sigal, M.
Frontiers in Endocrinology 15 : 1331231. 17 April 2024

Transient stabilization of human cardiovascular progenitor cells from human pluripotent stem cells in vitro reflects stage-specific heart development in vivo.
Bolesani, E., Bornhorst, D., Iyer, L.I., Zawada, D., Friese, N., Morgan, M., Lange, L., Gonzalez, D., Schrode, N., Leffler, A., Wunder, J., Franke, A., Drakhlis, L., Sebra, R., Schambach, A., Goedel, A., Dubois, N., Dobreva, G., Moretti, A., Zelarayán, L.C., Abdelilah-Seyfried, S. and Zweigerdt, R.
Cardiovascular Research 120 (11): 1295-1311. July 2024

Adiposity influences on myocardial deformation: a cardiovascular magnetic resonance feature tracking study in people with overweight to obesity without established cardiovascular disease.
Bolz, C., Blaszczyk, E., Mayr, T., Lim, C., Haufe, S., Jordan, J., Barckow, P., Gröschel, J. and Schulz-Menger, J.
International Journal of Cardiovascular Imaging 40 (3): 643-654. March 2024

Cognitive reserve and the risk of postoperative neurocognitive disorders in older age.
Borchers, F., Rumpel, M., Laubrock, J., Spies, C., Kozma, P., Slooter, A., van Montfort, S.J.T., Piper, S.K., Wiebach, J., Winterer, G., Pischon, T. and Feinkohl, I.
Frontiers in Aging Neuroscience 15 : 1327388. 5 February 2024

Inheritance of old mitochondria controls early CD8(+) T cell fate commitment and is regulated by autophagy.
Borsa, M., Lechuga-Vieco, A.V., Kayvanjoo, A.H., Yazicioglu, Y., Compeer, E.B., Richter, F.C., Bui, H., Dustin, M.L., Katajisto, P. and Simon, A.K.
bioRxiv : 2024.01.29.577412. 31 January 2024

Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.
Borsa, M., Obba, S., Richter, F.C., Zhang, H., Riffelmacher, T., Carrelha, J., Alsaleh, G., Jacobsen, S.E.W. and Simon, A.K.
Autophagy 20 (1): 45-57. January 2024

Functional autoantibodies against G protein-coupled receptors in hepatic and pulmonary hypertensions in human schistosomiasis.
Botoni, F.A., Lambertucci, J.R., Santos, R.A.S., Müller, J., Talvani, A. and Wallukat, G.
Frontiers in Immunology 15 : 1404384. 17 June 2024

Diet and physical activity as risk-reducing factors for hidradenitis suppurativa.
Bouwman, K., Moazzen, S., Kroah-Hartman, M., Dijkstra, G., Horváth, B. and Alizadeh, B.Z.
Journal of the European Academy of Dermatology and Venereology 38 (5): 910-919. May 2024

Fasting in science and clinics - a report on proceedings from the International Scientific Symposium and Conference on Fasting in Berlin (June 2023).
Breinlinger, C., Meiß, S., Hanslian, E., Jordan, St., Boschmann, M., Rajput Khokhar, A., Michalsen, A. and Koppold, D.A.
Complementary Medicine Research 31 (5): 484-491. October 2024

Epidemiology of myocarditis following COVID-19 or influenza and use of diagnostic assessments.
Butler, O., Raisi-Estabragh, Z., Han, Y., Frenz, A.K., Harz, C., Kelle, S., Schulz-Menger, J., Michel, A. and Kim, J.
Open Heart 11 (2): e002947. 9 November 2024

Microproteins encoded by noncanonical ORFs are a major source of tumor-specific antigens in a liver cancer patient meta-cohort.
Camarena, M.E., Theunissen, P., Ruiz, M., Ruiz-Orera, J., Calvo-Serra, B., Castelo, R., Castro, C., Sarobe, P., Fortes, P., Perera-Bel, J. and Albà, M.M.
Science Advances 10 (28): eadn3628. July 2024

Intramyocardial sprouting tip cells specify coronary arterialization.
Cano, E., Schwarzkopf, J., Kanda, M., Lindberg, E.L., Hollfinger, I., Pogontke, C., Braeuning, C., Fischer, C., Hübner, N. and Gerhardt, H.
Circulation Research 135 (6): 671-684. 30 August 2024

Beyond weight loss: the emerging role of incretin-based treatments in cardiometabolic HFpEF.
Capone, F., Nambiar, N. and Schiattarella, G.G.
Current Opinion in Cardiology 39 (2): 148-153. May 2024

SRRM2 splicing factor modulates cell fate in early development.
Carvalho, S., Zea-Redondo, L., Tang, T.C.C., Stachel-Braum, P., Miller, D., Caldas, P., Kukalev, A., Diecke, S., Grosswendt, S., Grosso, A.R. and Pombo, A.
Biology Open 13 (4): bio060415. April 2024

miR-7 controls glutamatergic transmission and neuronal connectivity in a Cdr1as-dependent manner.
Cerda Jara, C.A., Kim, S.J., Thomas, G., Farsi, Z., Zolotarov, G., Dube, G., Deter, A., Bahry, E., Georgii, E., Woehler, A., Piwecka, M. and Rajewsky, N.
EMBO Reports 25 (7): 3039. July 2024

Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome.
Chan, J.C., Alenina, N., Cunningham, A.M., Ramakrishnan, A., Shen, Li, Bader, M. and Maze, I.
Journal of Molecular Biology 436 (7): 168454. 1 April 2024

Baseline microbiome composition impacts resilience to and recovery following antibiotics.
Chen, C.Y., Löber, U., Bartolomaeus, H., Maier, L., Müller, D.N., Wilck, N., Jarquín-Díaz, V.H. and Forslund-Startceva, S.K.
bioRxiv : 2024.03.31.587491. 31 March 2024

Efficient recovery of complete gut viral genomes by combined short- and long-read sequencing.
Chen, J., Sun, C., Dong, Y., Jin, M., Lai, S., Jia, L., Zhao, X., Wang, H., Gao, N.L., Bork, P., Liu, Z., Chen, W.H. and Zhao, X.M.
Advanced Science 11 (13): 2305818. 3 April 2024

Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells.
Chiariello, A.M., Abraham, Alex, Bianco, S., Esposito, A., Fontana, A., Vercellone, F., Conte, M. and Nicodemi, M.
Nature Communications 15 (1): 4014. 13 May 2024

Protocol for assessing myogenic tone and perfusion pressure in isolated mouse kidneys.
Chu, Z., Kassmann, M., Anistan, Y.M., Luft, F.C., Gollasch, M. and Tsvetkov, D.
STAR Protocols 5 (1): 102845. 15 March 2024

Proposed diagnostic criteria for arrhythmogenic cardiomyopathy. European Task Force consensus report.
Corrado, D., Anastasakis, A., Basso, C., Bauce, B., Blomström-Lundqvist, C., Bucciarelli-Ducci, C., Cipriani, A., De Asmundis, C., Gandjbakhch, E., Jiménez-Jaimez, J., Kharlap, M., McKenna, W.J., Monserrat, L., Moon, J., Pantazis, A., Pelliccia, A., Perazzolo Marra, M., Pillichou, K., Schulz-Menger, J., Jurcut, R., Seferovic, P., Sharma, S., Tfelt-Hansen, J., Thiene, G., Wichter, T., Wilde, A. and Zorzi, A.
International Journal of Cardiology 395 : 131447. 15 January 2024

Next questions in autophagy.
Cuervo, A.M., Elazar, Z., Evans, C., Ge, L., Hansen, M., Jäättelä, M., Liang, J.R.A., Loos, B., Mizushima, N., Simon, A.K., Tooze, S., Yoshimori, T. and Nakamura, S.
Nature Cell Biology 26 (5): 661-666. May 2024

Genomic attributes of airway commensal bacteria and mucosa.
Cuthbertson, L., Löber, U., Ish-Horowicz, J.S., McBrien, C.N., Churchward, C., Parker, J.C., Olanipekun, M.T., Burke, C., McGowan, A., Davies, G.A., Lewis, K.E., Hopkin, J.M., Chung, K.F., O'Carroll, O., Faul, J., Creaser-Thomas, J., Andrews, M., Ghosal, R., Piatek, S., Willis-Owen, S.A.G., Bartolomaeus, T.U.P., Birkner, T., Dwyer, S., Kumar, N., Turek, E.M., William Musk, A, Hui, J., Hunter, M., James, A., Dumas, M.E., Filippi, S., Cox, M.J., Lawley, T.D., Forslund, S.K., Moffatt, M.F. and Cookson, W.O.C.
Communications Biology 7 (1): 171. 12 February 2024

Toward accurate and fast velocity quantification with 3D ultrashort TE phase-contrast imaging.
Degenhardt, K., Schmidt, S., Aigner, C.S., Kratzer, F.J., Seiter, D.P., Mueller, M., Kolbitsch, C., Nagel, A.M., Wieben, O., Schaeffter, T., Schulz-Menger, J. and Schmitter, S.
Magnetic Resonance in Medicine 91 (5): 1994-2009. May 2024

An integrated view of the structure and function of the human 4D nucleome.
Dekker, J., Oksuz, B.A., Zhang, Y., Wang, Y., Minsk, M.K., Kuang, S., Yang, L., Gibcus, J.H., Krietenstein, N., Rando, O., Xu, J., Janssens, D.H., Henikoff, S., Kukalev, A., Willemin, A., Winick-Ng, W., Kempfer, R., Pombo, A., Yu, M., Kumar, P., Zhang, L., Belmont, A.S., Sasaki, T., van Schaik, T., Brueckner, L., Peric-Hupkes, D., van Steensel, B., Wang, P., Chai, H., Kim, M., Ruan, Y., Zhang, R., Quinodoz, S.A., Bhat, P., Guttman, M., Zhao, W., Chien, S., Liu, Y., Venev, S.V., Plewczynski, D., Irastorza Azcarate, I., Szabo, D., Thieme, C.J., Szczepinska, T., Chilinski, M., Sengupta, K., Conte, M., Esposito, A., Abraham, A., Zhang, R., Wang, Y., Wen, X., Wu, Q., Yang, Y., Liu, J., Boninsegna, L., Yildirim, A., Zhan, Y., Chiariello, A.M., Bianco, S., Lee, L., Hu, M., Li, Y., Barnett, R.., Cook, A.L., Emerson, D.J., Marchal, C., Zhao, P., Park, P., Alver, B.H., Schroeder, A., Navelkar, R., Bakker, C., Ronchetti, W., Ehmsen, S., Veit, A., Gehlenborg, N., Wang, T., Li, D., Wang, X., Nicodemi, M., Ren, B., Zhong, S., Phillips-Cremins, J.E., Gilbert, D.M., Pollard, K.S., Alber, F., Ma, J., Noble, W.S. and Yue, F.
bioRxiv : 2024.09.17.613111v2. 27 October 2024

High-quality peptide evidence for annotating non-canonical open reading frames as human proteins.
Deutsch, Eric W, Kok, Leron W, Mudge, Jonathan M, Ruiz-Orera, J., Fierro-Monti, Ivo, Sun, Zhi, Abelin, Jennifer G, Alba, M Mar, Aspden, Julie L, Bazzini, Ariel A, Bruford, Elspeth, Brunet, Marie A, Calviello, L., Carr, Steven A, Carvunis, Anne-Ruxandra, Chothani, Sonia, Clauwaert, Jim, Dean, Kellie, Faridi, Pouya, Frankish, Adam, Hubner, N., Ingolia, Nicholas, Magrane, Michele, Martin, Maria Jesus, Martinez, Thomas F, Menschaert, Gerben, Ohler, U., Orchard, Sandra, Rackham, Owen, Roucou, Xavier, Slavoff, Sarah A, Valen, Eivind, Wacholder, Aaron C, Weissman, Jonathan S., Wu, Wei, Xie, Zhi, Choudhary, Jyoti, Bassani-Sternberg, Michal, Vizcaino, Juan Antonio, Ternette, Nicola, Moritz, Robert L., Prensner, John and van Heesch, S.
bioRxiv : 2024.09.09.612016. 9 September 2024

Pharmacological inhibition of cathepsin S and of NSPs-AAP-1 (a novel, alternative protease driving the activation of neutrophil serine proteases).
Domain, R., Seren, S., Jerke, U., Makridakis, M., Chen, K.J., Zoidakis, J., Rhimi, M., Zhang, X., Bonvent, T., Croix, C., Gonzalez, L., Li, D., Basso, J., Paget, C., Viaud-Massuard, M.C., Lalmanach, G., Shi, G.P., Aghdassi, A., Vlahou, A., McDonald, P.P., Couillin, I., Williams, R., Kettritz, R. and Korkmaz, B.
Biochemical Pharmacology 229 : 116114. November 2024

A catalog of small proteins from the global microbiome.
Duan, Y., Santos-Júnior, C.D., Schmidt, T.S., Fullam, A., de Almeida, B.L.S., Zhu, C., Kuhn, M., Zhao, X.M., Bork, P. and Coelho, L.P.
Nature Communications 15 (1): 7563. 31 August 2024

Prospects for leveraging the microbiota as medicine for hypertension.
Durgan, D.J., Zubcevic, J., Vijay-Kumar, M., Yang, T., Manandhar, I., Aryal, S., Muralitharan, R.R., Li, H.B., Li, Y., Abais-Battad, J.M., Pluznick, J.L., Muller, D.N., Marques, F.Z. and Joe, B.
Hypertension 81 (5): 951-963. May 2024

Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice.
Dörmann, N., Hammer, E., Struckmann, K., Rüdebusch, J., Bartels, K., Wenzel, K., Schulz, J., Gross, S., Schwanz, S., Martin, E., Fielitz, B., Pablo Tortola, C., Hahn, A., Benkner, A., Völker, U., Felix, S.B and Fielitz, J.
Frontiers in Cardiovascular Medicine 10 : 1323760. 8 January 2024

Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner, P.J., Anandakumar, H., Röwekamp, I., Fiocca Vernengo, F., Millet Pascual-Leone, B., Krzanowski, M., Sellmaier, J., Brüning, U., Fritsche-Guenther, R., Pfannkuch, L., Kurth, F., Milek, M., Igbokwe, V., Löber, U., Gutbier, B., Holstein, M., Heinz, G.A., Mashreghi, M.F., Schulte, L.N., Klatt, A.B., Caesar, S., Wienhold, S.M., Offermanns, S., Mack, M., Witzenrath, M., Jordan, S., Beule, D., Kirwan, J.A., Forslund, S.K., Wilck, N., Bartolomaeus, H., Heimesaat, M.M. and Opitz, B.
Nature Communications 15 (1): 2788. 30 March 2024

Effects of a short-term vegan challenge in older adults on metabolic and inflammatory parameters - a randomized controlled crossover study.
Döschner, L., Schulze, K., Göger, L., Bosy-Westphal, A., Krüger, N., Franz, K., Müller-Werdan, U., Herpich, C. and Norman, K.
Molecular Nutrition & Food Research 68 (4): e2300623. February 2024

Targeted perturb-seq reveals EGR1 and FOS as key regulators of the transcriptional RAF-MAPK response.
El Kassem, G., Sieber, A., Klinger, B., Uhlitz, F., Steinbrecht, D., van Bentum, M., Hillmer, J., von Schlichting, J., Schäfer, R., Blüthgen, N. and Boettcher, M.
bioRxiv : 2024.01.13.575500. 15 January 2024

Protein intake and body weight, fat mass and waist circumference: an umbrella review of systematic reviews for the evidence-based guideline on protein intake of the German Nutrition Society.
Ellinger, S., Amini, A.M., Haardt, J., Lehmann, A., Schmidt, A., Bischoff-Ferrari, H.A., Buyken, A.E., Kroke, A., Kühn, T., Louis, S., Lorkowski, S., Nimptsch, K., Schulze, M.B., Schwingshackl, L., Siener, R., Stangl, G.I., Volkert, D., Zittermann, A., Watzl, B. and Egert, S.
European Journal of Nutrition 63 (1): 3-32. February 2024

Insulin secretion defect in children and adolescents with obesity: clinical and molecular genetic characterization.
Enders-Seidlitz, H., Raile, K., Gong, M., Galler, A., Kuehnen, P. and Wiegand, S.
Journal of Diabetes Research 2024 : 5558634. 20 March 2024

The evolving landscape of cardiometabolic diseases.
Eroglu, T., Capone, F. and Schiattarella, G.G.
EBioMedicine 109 : 105447. November 2024

Intermuscular adipose tissue accumulation is associated with higher tissue sodium in healthy individuals.
Ertuglu, L.A., Sahinoz, M., Alsouqi, A., Deger, S.M., Guide, A., Pike, M., Robinson-Cohen, C., Akwo, E., Pridmore, M., Crescenzi, R., Madhur, M.S., Kirabo, A., Harrison, D.G., Luft, F.C., Titze, J., Ikizler, T.A. and Gamboa, J.L.
Physiological Reports 12 (13): e16127. July 2024

Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19.
Essex, M., Millet Pascual-Leone, B.L., Löber, U., Kuhring, M., Zhang, B., Brüning, U., Fritsche-Guenther, R., Krzanowski, M., Fiocca Vernengo, F., Brumhard, S., Röwekamp, I., Bielecka, A.A., Lesker, T.R., Wyler, E., Landthaler, M., Mantei, A., Meisel, C., Caesar, S., Thibeault, C., Corman, V.M., Marko, L., Suttorp, N., Strowig, T., Kurth, F., Sander, L.E., Li, Y., Kirwan, J.A., Forslund, S.K. and Opitz, B.
NPJ Biofilms and Microbiomes 10 (1): 66. 1 August 2024

Shared and distinct gut microbiota in spondyloarthritis, acute anterior uveitis, and Crohn's disease.
Essex, M., Rios Rodriguez, V., Rademacher, J., Proft, F., Löber, U., Marko, L., Pleyer, U., Strowig, T., Marchand, J., Kirwan, J.A., Siegmund, B., Forslund, S.K. and Poddubnyy, D.
Arthritis & Rheumatology 76 (1): 48-58. January 2024

The diversity of the microbiome impacts chronic lymphocytic leukemia development in mice and humans.
Faitova, T., Coelho, M., Da Cunha-Bang, C., Ozturk, S., Kartal, E., Bork, P., Seiffert, M. and Niemann, C.U.
Haematologica 109 (10): 3237-3250. October 2024

The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
Fasciani, I., Petragnano, F., Wang, Z., Edwards, R., Telugu, N., Pietrantoni, I., Zabel, U., Zauber, H., Grieben, M., Terzenidou, M.E., Di Gregorio, J., Pellegrini, C., Santini, S., Taddei, A.R., Pohl, B., Aringhieri, S., Carli, M., Aloisi, G., Marampon, F., Charlesworth, E., Roman, A., Diecke, S., Flati, V., Giorgi, F., Amicarelli, F., Tobin, A.B., Scarselli, M., Tokatlidis, K., Rossi, M., Lohse, M.J., Annibale, P. and Maggio, R.
PLoS Biology 22 (4): e3002582. 29 April 2024

Determinants of ascending aortic morphology: Cross-sectional deep learning-based analysis on 25,073 non-contrast-enhanced MRI of NAKO.
Fay, L., Hepp, T., Winkelmann, M.T., Peters, A., Heier, M., Niendorf, T., Pischon, T., Endemann, B., Schulz-Menger, J., Krist, L., Schulze, M.B., Mikolajczyk, R., Wienke, A., Obi, N., Silenou, B.C., Lange, B., Kauczor, H.U., Lieb, W., Baurecht, H., Leitzmann, M., Trares, K., Brenner, H., Michels, K.B., Jaskulski, St., Völzke, H., Nikolaou, K., Schlett, C.L., Bamberg, F., Lescan, M., Yang, B., Küstner, T. and Gatidis, S.
medRxiv : 2024.07.12.24310356. 15 July 2024

The association of plasma leptin, soluble leptin receptor and total and high-molecular weight adiponectin with the risk of perioperative neurocognitive disorders.
Feinkohl, I., Janke, J., Slooter, A.J.C., Winterer, G., Spies, C. and Pischon, T.
American Journal of Geriatric Psychiatry 32 (9): 1119-1129. September 2024

Cardiovascular magnetic resonance reveals myocardial involvement in patients with active stage of inflammatory bowel disease.
Fenski, M., Abazi, E., Gröschel, J., Hadler, T., Kappelmayer, D., Kolligs, F., Prieto, C., Botnar, R., Kunze, K.P. and Schulz-Menger, J.
Clinical Research in Cardiology 5 August 2024 (In Press)

Role of kinin receptors in skin pigmentation.
Ferreira, J.C.P., Soley, B.S., Pawloski, P.L., Moreira, C.G., Pesquero, J.B., Bader, M., Calixto, J.B., Cabrini, D.A. and Otuki, M.F.
European Journal of Pharmacology 973 : 176537. 15 June 2024

Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients.
Fislage, M., Winzeck, S., Woodrow, R., Lammers-Lietz, F., Stamatakis, E.A., Correia, M.M., Preller, J., Feinkohl, I., Hendrikse, J., Pischon, T., Spies, C.D., Slooter, A.J.C., Winterer, G., Menon, D.K. and Zacharias, N.
Alzheimer's and Dementia 20 (4): 2861-2872. April 2024

L-glyceraldehyde inhibits neuroblastoma cell growth via a multi-modal mechanism on metabolism and Signaling.
Forbes, M., Kempa, R., Mastrobuoni, G., Rayman, L., Pietzke, M., Bayram, S., Arlt, B., Spruessel, A., Deubzer, H.E. and Kempa, S.
Cancers 16 (9): 1664. May 2024

Mitophagy modulation for the treatment of cardiovascular diseases.
Forte, M., D'Ambrosio, L., Schiattarella, G.G., Salerno, N., Perrone, M.A., Loffredo, F.S., Bertero, E., Pilichou, K., Manno, G., Valenti, V., Spadafora, L., Bernardi, M., Simeone, B., Sarto, G., Frati, G., Perrino, C. and Sciarretta, S.
European Journal of Clinical Investigation 54 (8): e14199. August 2024

Effects of bradykinin B2 receptor ablation from tyrosine hydroxylase cells on behavioral and motor aspects in male and female mice.
Franco, T.M., Tavares, M.R., Novaes, L.S., Munhoz, C.D., Peixoto-Santos, J.E., Araujo, R.C., Donato, J., Bader, M. and Wasinski, F.
International Journal of Molecular Sciences 25 (3): 1490. 25 January 2024

Activation mapping in multi-center rat sensory-evoked functional MRI datasets using a unified pipeline.
Galteau, M.E., Broadwater, M., Chen, Y., Desrosiers-Gregoire, G., Gil, R., Kaesser, J., Kim, E., Kiryagdi, P., Lambers, H., Liu, Y.Y., Lopez-Gil, X., MacNicol, E., Mohebkhodaei, P., De Oliveira, R.X.N., Pereira, C.A., Reimann, H.M., Rivera-Olvera, Al., Selingue, E., Sirmpilatze, N., Strobelt, S., Sumiyoshi, A., Tham, C., Tudela, R., Vrooman, R.M., Wank, I., Zhang, Y., van Engelenburg, W.A., Baudewig, J., Boretius, S., Cash, D., Chakravarty, M.M., Chuang, K.H., Ciobanu, L., Devenyi, G.A., Faber, C., Hess, A., Homberg, J.R., Jelescu, I.O., Justicia, C., Kawashima, R., Niendorf, T., Scheenen, T.W.J., Shemesh, N., Soria, G., Todd, N., Wachsmuth, L., Yu, X., Zhang, B.B., Shih, Y.Y.I., Lee, S.H. and Grandjean, J.
bioRxiv : 2024.09.27.615384. 30 September 2024

YAP/TAZ signaling in allantois-derived cells is required for placental vascularization.
Gao, S., Thillaikumaran, T., Dominguez, M.H., Giang, W., Hayes, K., Chen, X., Pace, J., Bockman, J., Jathan, D., Sung, D., Narayan, S., Frankfurter, M., Mericko-Ishizuka, P., Yang, J., Castro, M., Potente, M. and Kahn, M.L.
bioRxiv : 2024.09.15.613151. 16 September 2024

iSuRe-HadCre is an essential tool for effective conditional genetics.
Garcia-Gonzalez, I., Rocha, S.F., Hamidi, A., Garcia-Ortega, L., Regano, A., Sanchez-Muñoz, M.S., Lytvyn, M., Garcia-Cabero, A., Roig-Soucase, S., Schoofs, H., Castro, M., Sabata, H., Potente, M., Graupera, M., Makinen, T. and Benedito, R.
Nucleic Acids Research 52 (13): e56. 22 July 2024

Emergence of community behaviors in the gut microbiota upon drug treatment.
Garcia-Santamarina, S., Kuhn, M., Devendran, S., Maier, L., Driessen, M., Mateus, A., Mastrorilli, E., Brochado, A.R., Savitski, M.M., Patil, K.R., Zimmermann, M., Bork, P. and Typas, A.
Cell 187 (22): 6346-6357.e20. 31 October 2024

Stress CMR Perfusion Imaging in the Medicare-Eligible Population: Insights From the SPINS Study.
Ge, Y., Antiochos, P., Bernhard, B., Heydari, B., Steel, K., Bingham, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Shanbhag, S.M., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 16 October 2024 (In Press)

Polarity-JaM: An image analysis toolbox for cell polarity, junction and morphology quantification.
Giese, W., Albrecht, J.P., Oppenheim, O., Akmeriç, E.B., Kraxner, J., Schmidt, D., Harrington, K.I. and Gerhardt, H.
bioRxiv : 2024.01.24.577027v2. 27 April 2024

Mechanical strain activates planar cell polarity signaling to coordinate vascular cell dynamics.
Golbach, L., Saha, T., Odenthal-Schnittler, M., Lücking, J., Velic, A., Akmeric, E.B., Bornhorst, D., Popp, O., Mertins, P., Gunawan, F., Gerhardt, H., Macek, B., Trappmann, B., Schnittler, H.J., Galic, M. and Matis, M.
bioRxiv : 2024.06.25.600357. 26 June 2024

SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction.
Gotthardt, M. and Lehnart, S.E.
Cardiovascular Research 120 (3): 220-222. February 2024

Costs associated with insufficient physical activity in Germany: cross-sectional results from the baseline examination of the German national cohort (NAKO).
Gottschalk, S., König, H.H., Weber, A., Leitzmann, M.F., Stein, M.J., Peters, A., Flexeder, C., Krist, L., Willich, S.N., Nimptsch, K., Pischon, T., Gastell, S., Steindorf, K., Herbolsheimer, F., Ebert, N., Michels, K.B., Dorrn, A., Harth, V., Obi, N., Karch, A., Teismann, H., Völzke, H., Meinke-Franze, C., Klimeck, L., Seum, T.L. and Dams, J.
European Journal of Health Economics 10 May 2024 (In Press)

Detecting unforeseen data properties with diffusion autoencoder embeddings using spine MRI data.
Graf, R., Hunecke, F., Pohl, S., Atad, M., Moeller, H., Starck, S., Kroencke, T., Bette, S., Bamberg, F., Pischon, T., Niendorf, T., Schmidt, C., Paetzold, J.C., Rueckert, D. and Kirschke, J.S.
arXiv : 2410.10220. 14 October 2024

Extracellular matrix remodeling in atopic dermatitis harnesses the onset of an asthmatic phenotype and is a potential contributor to the atopic march.
Graff, P., Woerz, D., Wilzopolski, J., Voss, A., Sarrazin, J., Blimkie, T.M., Weiner, J., Kershaw, O., Panwar, P., Hackett, T., Lau, S., Brömme, D., Beule, D., Lee, Y.A., Hancock, R.E.W., Gruber, A.D., Bäumer, W. and Hedtrich, S.
Journal of Investigative Dermatology 144 (5): 1010-1021. May 2024

Sex-specific structural and functional cardiac remodeling during healthy aging assessed by cardiovascular magnetic resonance.
Grassow, L., Gröschel, J., Saad, H., Krüger, L.D., Kuhnt, J., Müller, M., Hadler, T., Blaszczyk, E. and Schulz-Menger, J.
Clinical Research in Cardiology 11 March 2024 (In Press)

Interaction of sortilin with apolipoprotein E3 enables neurons to use long-chain fatty acids as alternative metabolic fuel.
Greda, A.K., Gomes, J.P., Zurawska-Plaksej, E., Fritsche-Guenther, R., Rudolph, I.M., Telugu, N.S., Cömert, C., Kirwan, J., Kunz, S., Rothe, M., Diecke, S., Bross, P. and Willnow, T.E.
bioRxiv : 2024.06.10.598173. 10 June 2024

CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.
Greensmith, R., Lape, I.T., Riella, C.V., Schubert, A.J., Metzger, J.J., Dighe, A.S., Tan, X., Hemmer, B., Rau, J., Wendlinger, S., Diederich, N., Schütz, A., Riella, L.V. and Kaminski, M.M.
EMBO Molecular Medicine 16 (10): 2619-2637. 14 October 2024

Kinin B1 receptor modulates glucose homeostasis and physical exercise capacity by altering adrenal catecholamine synthesis and secretion.
Gregnani, M.F., Budu, A., Batista, R.O., Ornellas, F.H., Estrela, G.R., Arruda, A.C., Freitas-Lima, L.C., Kremer, J.L., Favaroni Mendes, L.A., Casarini, D.E., Lotfi, C.F.P., Oyama, L.M., Bader, M. and Araujo, R.C.
Molecular and Cellular Endocrinology 579 : 112085. 1 January 2024

Deep cardiac phenotyping by cardiovascular magnetic resonance reveals subclinical focal and diffuse myocardial injury in patients with psoriasis (PSOR‑COR study).
Gröschel, J., Grassow, L., Blaszczyk, E., Lommel, K., Kokolakis, G., Sabat, R. and Schulz-Menger, J.
Clinical Research in Cardiology 16 May 2024 (In Press)

Trajectories of functional and structural myocardial parameters in post-COVID-19 syndrome - insights from mid-term follow-up by cardiovascular magnetic resonance.
Gröschel, J., Grassow, L., van Dijck, P., Bhoyroo, Y., Blaszczyk, E. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 11 : 1357349. 2 April 2024

Comparison of manual and artificial intelligence based quantification of myocardial strain by feature tracking - a cardiovascular MR study in health and disease.
Gröschel, J., Kuhnt, J., Viezzer, D., Hadler, T., Hormes, S., Barckow, P., Schulz-Menger, J. and Blaszczyk, E.
European Radiology 34 (2): 1003-1015. February 2024

Integration of CTCF loops, methylome, and transcriptome in differentiating LUHMES as a model for imprinting dynamics of the 15q11-q13 locus in human neurons.
Gutierrez Fugón, O.J., Sharifi, O., Heath, N., Soto, D.C., Gomez, J.A., Yasui, D.H., Mendiola, A.J.P., O'Geen, He., Beitnere, U., Tomkova, M., Haghani, V., Dillon, G., Segal, D.J. and LaSalle, J.M.
Human Molecular Genetics 33 (19): 1711-1725. 1 October 2024

Comparing the extraction performance in mouse plasma of different biphasic methods for polar and nonpolar compounds.
Gutmann, F., Fritsche-Guenther, R., Dias, D.B. and Kirwan, J.A.
Journal of Proteome Research 23 (8): 2961-2969. 2 August 2024

Personality and the use of cancer screenings - Results of the German National Cohort.
Hajek, A., Becher, H., Brenner, H., Holleczek, B., Katzke, V., Kaaks, R., Minnerup, H., Karch, A., Baurecht, H., Leitzmann, M., Peters, A., Gastell, S., Ahrens, W., Haug, U., Nimptsch, K., Pischon, T., Michels, K.B., Dorrn, A., Klett-Tammen, C., Castell, S., Willich, S.N., Keil, T., Schipf, S., Meinke-Franze, C., Harth, V., Obi, N. and König, H.H.
Preventive Medicine Reports 41 : 102677. May 2024

MR beyond diagnostics at the ESMRMB annual meeting: MR theranostics and intervention.
Hajek, M., Flögel, U., Tavares, A., Nichelli, L., Kennerley, A., Kahn, T., Futterer, J., Firsiori, A., Grüll, H., Saha, N., Couñago, F., Aydogan, D.B., Caligiuri, M.E., Faber, C., Bell, L.C., Figueiredo, P., Vilanova, J.C., Santini, F., Mekle, R. and Waiczies, S.
Magnetic Resonance Materials in Physics, Biology and Medicine 37 (3): 323-328. July 2024

Reproducibility assessment of rapid strains in cardiac MRI: Insights and recommendations for clinical application.
Halfmann, M.C., Hopman, L.H.G.A., Körperich, H., Blaszczyk, E., Gröschel, J., Schulz-Menger, J., Salatzki, J., André, F., Friedrich, S. and Emrich, T.
European Journal of Radiology 174 : 111386. May 2024

Using paired-end read orientations to assess technical biases in capture Hi-C.
Hansen, P., Blau, H., Hecht, J., Karlebach, G., Krannich, A., Steinhaus, R., Truss, M. and Robinson, P.N.
NAR Genomics and Bioinformatics 6 (4): lqae156. December 2024

Tail-cuff versus radiotelemetry to measure blood pressure in mice and rats.
Harrison, D.G., Bader, M., Lerman, L.O., Fink, G., Karumanchi, S.A., Reckelhoff, J.F., Sequeira-Lopez, M.L.S. and Touyz, R.M.
Hypertension 81 (1): 3-5. January 2024

p53 terminates the regenerative fetal-like state after colitis-associated injury.
Hartl, K., Bayram, Ş., Wetzel, A., Harnack, C., Lin, M., Fischer, A.S., Liu, L., Beccacec, G., Mastrobuoni, G., Geisberger, S., Forbes, M., Monteiro, B.J.E., Macino, M., Flores, R.E., Engelmann, C., Mollenkopf, H.J., Schupp, M., Tacke, F., Sanders, A.D., Kempa, S., Berger, H. and Sigal, M.
Science Advances 10 (43): eadp8783. 25 October 2024

A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI).
Hartmann, C.R., Khan, R., Schöning, J., Richter, M., Willers, M., Pirr, S., Heckmann, J., Dirks, J., Morbach, H., Konrad, M., Fries, E., Winkler, M., Büchel, J., Seidenspinner, S., Fischer, J., Vollmuth, C., Meinhardt, M., Marissen, J., Schmolke, M., Haid, S., Pietschmann, T., Backes, S., Dölken, L., Löber, U., Keil, T., Heuschmann, P.U., Wöckel, A., Sagar, Dr., Ulas, T., Forslund-Startceva, S.K., Härtel, C. and Viemann, D.
Frontiers in Immunology 15 : 1443665. 17 September 2024

The effects of hypoxia on the immune-metabolic interplay in liver cancer.
He, Y., Xu, H., Liu, Y., Kempa, S., Vechiatto, C., Schmidt, R., Yilmaz, E.Y., Heidemann, L., Schnorr, J., Metzkow, S., Schellenberger, E., Häckel, A., Patzak, A., Müller, D.N. and Savic, L.J.
Biomolecules 14 (8): 1024. 17 August 2024

Mutations in CLCN6 as a novel genetic cause of neuronal ceroid lipofuscinosis in patients and a murine model.
He, H., Cao, X., He, F., Zhang, W., Wang, X., Peng, P., Xie, C., Yin, F., Li, D., Li, J., Wang, M., Klüssendorf, M., Jentsch, T.J., Stauber, T. and Peng, J.
Annals of Neurology 96 (3): 608-624. September 2024

Perioperative levels of IL8 and IL18, but not IL6, are associated with nucleus basalis magnocellularis atrophy three months after surgery.
Heinrich, M., Spies, C., Borchers, F., Feinkohl, I., Pischon, T., Slooter, A.J.C., von Haefen, C., Zacharias, N., Winterer, G. and Lammers-Lietz, F.
Journal of Neuroimmune Pharmacology 19 (1): 10. 14 March 2024

Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response.
Hendrickson, T., Giese, A., Fiedler, M., Perez, W., Reyes-Sanchez, E., Reyes-Lozano, M., Wang, S., Venegas-Zamora, L., Provasek, V., El-Essawi, A., Breitenbach, I., Fakuade, F.E., Kutschka, I., Schiattarella, G.G., Voigt, N., Valderrabano, M. and Altamirano, F.
bioRxiv : 2024.07.08.602618. 12 July 2024

Changes in physical activity and sedentary behavior during the first COVID-19 pandemic- restrictions in Germany: a nationwide survey : Running head: physical activity during the COVID-19 restrictions.
Herbolsheimer, F., Peters, A., Wagner, S., Willich, S.N., Krist, L., Pischon, T., Nimptsch, K., Gastell, S., Brandes, M., Brandes, B., Schikowski, T., Schmidt, B., Michels, K.B., Mikolajczyk, R., Harth, V., Obi, N., Castell, S., Heise, J.K., Lieb, W., Franzpötter, K., Karch, A., Teismann, H., Völzke, H., Meinke-Franze, C., Leitzmann, M., Stein, M.J., Brenner, H., Holleczek, B., Weber, A., Bohn, B., Kluttig, A. and Steindorf, K.
BMC Public Health 24 (1): 433. 12 February 2024

Cell-mechanical parameter estimation from 1D cell trajectories using simulation-based inference.
Heyn, J., Atienza Juanatey, M., Falcke, M. and Raedler, J.
bioRxiv : 2024.09.06.611766. 8 September 2024

Mesenchymal cell migration on one-dimensional micropatterns.
Heyn, J.C.J., Rädler, J.O. and Falcke, M.
Frontiers in Cell and Developmental Biology 12 : 1352279. 16 April 2024

Nourishing the mind: fasting for brain health.
Hofer, S.J. and Madeo, F.
Cell Metabolism 36 (8): 1635-1637. 6 August 2024

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Hofman, D.A., Ruiz-Orera, J., Yannuzzi, I., Murugesan, R., Brown, A., Clauser, K.R., Condurat, A.L., van Dinter, J.T., Engels, S.A.G., Goodale, A., van der Lugt, J., Abid, T., Wang, L., Zhou, K.N., Vogelzang, J., Ligon, K.L., Phoenix, T.N., Roth, J.A., Root, D.E, Hubner, N., Golub, T.R., Bandopadhayay, P., van Heesch, S. and Prensner, J.R.
Molecular Cell 84 (2): 261-276. 18 January 2024

Gut dysbiosis contributes to TMAO accumulation in CKD.
Holle, J., McParland, V., Anandakumar, H., Gerritzmann, F., Behrens, F., Schumacher, F., Thumfart, J., Eckardt, K.U., Kleuser, B., Bartolomaeus, H. and Wilck, N.
Nephrology Dialysis Transplantation 39 (11): 1923-1926. November 2024

Gut microbiome alterations precede graft rejection in kidney transplantation patients.
Holle, J., Reitmeir, R., Behrens, F., Singh, D., Schindler, D., Potapenko, O., McParland, V., Anandakumar, H., Kanzelmeyer, N., Sommerer, C., Hartleif, S., Andassy, J., Heemann, U., Neuenhahn, M., Forslund-Startceva, S.K., Gerhard, M., Oh, J., Wilck, N., Löber, U. and Bartolomaeus, H.
medRxiv : 2024.05.21.24307660. 21 May 2024

Childhood and adolescence factors and multiple sclerosis: results from the German National Cohort (NAKO).
Holz, A., Obi, N., Ahrens, W., Berger, K., Bohn, B., Brenner, H., Fischer, B., Fricke, J., Führer, A., Gastell, S., Greiser, K.H., Harth, V., Heise, J.K., Holleczek, B., Keil, T., Klett-Tammen, C.J., Leitzmann, M., Lieb, W., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Nimptsch, K., Peters, A., Pischon, T., Riedel, O., Schikowski, T., Schipf, S., Schmidt, B., Schulze, M.B., Stang, A., Hellwig, K., Riemann-Lorenz, K., Heesen, C. and Becher, H.
BMC Neurology 24 : 123. 13 April 2024

Quantification of myocardial effective transverse relaxation time with magnetic resonance at 7.0 Tesla for a better understanding of myocardial (patho)physiology.
Huelnhagen, T., Serradas-Duarte, T., Hezel, F., Paul, K. and Niendorf, T.
In: Quantification of Biophysical Parameters in Medical Imaging. Springer, Cham, Switzerland, 381-406. ISBN 978-3-031-61846-8 5 November 2024

3D whole heart k-space-based super-resolution cardiac T1 mapping using rotated stacks.
Hufnagel, S., Schuenke, P., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Physics in Medicine and Biology 69 (8): 085027. 9 April 2024

Microglia from patients with multiple sclerosis display a cell-autonomous immune activation state.
Hyvärinen, T., Lotila, J., Giudice, L., Tujula, I., Nylund, M., Ohtonen, S., Scoyni, F., Jäntti, H., Pihlava, S., Skottman, H., Narkilahti, S., Airas, L., Malm, T. and Hagman, S.
bioRxiv : 2024.12.10.627477. 11 December 2024

Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies.
Hüttemeister, J., Rudolph, F., Radke, M.H., Fink, C., Friedrich, D., Preibisch, S., Falcke, M., Wagner, E., Lehnart, S.E. and Gotthardt, M.
bioRxiv : 2024.02.01.578471. 7 February 2024

Extensive folding variability between homologous chromosomes in mammalian cells.
Irastorza-Azcarate, I., Kukalev, A., Kempfer, R., Thieme, C.J., Mastrobuoni, G., Markowski, J., Loof, G., Sparks, T.M., Brookes, E., Natarajan, K.N., Sauer, S., Fisher, A.G., Nicodemi, M., Ren, B., Schwarz, R.F., Kempa, S. and Pombo, A.
bioRxiv : 2024.05.08.591087. 10 May 2024

Non-viral targeted insertion of large payloads into T cells.
Izsvak, Z.
Nature Biomedical Engineering 16 September 2024 (In Press)

Aberrant microbiomes are associated with increased antibiotic resistance gene load in hybrid mice.
Jarquín-Díaz, V.H., Ferreira, S.C.M., Balard, A., Ďureje, L., Macholán, M., Piálek, J., Bengtsson-Palme, J., Kramer-Schadt, S., Forslund-Startceva, S.K. and Heitlinger, E.
ISME Communications 4 (1): ycae053. 15 April 2024

Quantifying model uncertainty for semantic segmentation of Fluorine-19 MRI using stochastic gradient MCMC.
Javanbakhat, M., Starke, L., Waiczies, S. and Lippert, C.
Computer Vision and Image Understanding 241 : 103967. April 2024

Use of mesna prophylaxis in patients with cyclophosphamide-treated ANCA-associated vasculitis: cross-sectional survey of practitioners.
Joos, L., Gonzalez Chiappe, S., Neumann, T. and Mahr, A.
Rheumatology International 44 (12): 3099-3106. December 2024

Dentition patterns and molecular diversity of Mastophorus muris (Gmelin, 1790) (Nematoda: Spiruroidea) support a host-associated subdivision.
Jost, J., Hirzmann, J., Ďureje, Ľ., Maaz, D., Martin, P., Stach, T., Heitlinger, E. and Jarquín-Díaz, V.H.
Parasitology Research 123 (6): 237. June 2024

A gender perspective on diet, microbiome, and sex hormone interplay in cardiovascular disease.
Jovanovic, N., Zach, V., Crocini, C., Bahr, L.S., Forslund-Startceva, S.K. and Franz, K.
Acta Physiologica 240 (11): e14228. November 2024

An altered plasma lipidome-phenome network characterizes heart failure with preserved ejection fraction.
Jovanovic, N., Foryst-Ludwig, A., Klose, C., da Conceicao, C.R., Alasfar, L., Birkner, T., Forslund, S.K., Kintscher, U. and Edelmann, F.
ESC Heart Failure 11 (3): 1553-1566. June 2024

Deep learning-based body composition analysis from whole-body magnetic resonance imaging to predict all-cause mortality in a large western population.
Jung, M., Raghu, V.K., Reisert, M., Rieder, H., Rospleszcz, S., Pischon, T., Niendorf, T., Kauczor, H.U., Völzke, H., Bülow, R., Russe, M.F., Schlett, C.L., Lu, M.T., Bamberg, F. and Weiss, J.
EBioMedicine 110 : 105467. December 2024

SetQuence & SetOmic: deep set transformers for whole genome and exome tumour analysis.
Jurenaite, N., León-Periñán, D., Donath, V., Torge, S. and Jäkel, R.
Biosystems 235 : 105095. January 2024

Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment.
Juul-Madsen, K., Parbo, P., Ismail, R., Ovesen, P.L., Schmidt, V., Madsen, L.S., Thyrsted, J., Gierl, S., Breum, M., Larsen, A., Andersen, M.N., Romero-Ramos, M., Holm, C.K., Andersen, G.R., Zhao, H., Schuck, P., Nygaard, J.V., Sutherland, D.S., Eskildsen, S.F., Willnow, T.E., Brooks, D.J. and Vorup-Jensen, T.
Nature Communications 15 (1): 1224. 9 February 2024

Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment.
Kaiser, R., Gold, C., Joppich, M., Loew, Q., Akhalkatsi, A., Mueller, T.T., Offensperger, F., Droste Zu Senden, A., Popp, O., di Fina, L., Knottenberg, V., Martinez-Navarro, A., Eivers, L., Anjum, A., Escaig, R., Bruns, N., Briem, E., Dewender, R., Muraly, A., Akgöl, S., Ferraro, B., Hoeflinger, J.K.L., Polewka, V., Khaled, N.B., Allgeier, J., Tiedt, S., Dichgans, M., Engelmann, B., Enard, W., Mertins, P., Hubner, N., Weckbach, L., Zimmer, R., Massberg, S., Stark, K., Nicolai, L. and Pekayvaz, K.
Science Advances 10 (12): eadl1710. 22 March 2024

Tolerance induction through early feeding to prevent food allergy in infants and children with sensitization against food allergens (TIFFANI): rationale, study design, and methods of a randomized controlled trial.
Kalb, B., Meixner, L., Heller, S., Dölle-Bierke, S., Roll, S., Tissen-Diabaté, T., Lau, S., Forslund, S., Marenholz, I., Lee, Y.A., Thiel, A., Babina, M., Scheffel, J., Worm, M. and Beyer, K.
Trials 25 : 272. 19 April 2024

SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells.
Kalnytska, O., Qvist, P., Kunz, S., Conrad, T., Willnow, T.E. and Schmidt, V.
iScience 27 (1): 108725. 19 January 2024

SorLA restricts TNFα release from microglia to shape a glioma-supportive brain microenvironment.
Kaminska, P., Ovesen, P.L., Jakiel, M., Obrebski, T., Schmidt, V., Draminski, M., Bilska, A.G., Bieniek, M., Anink, J., Paterczyk, B., Jensen, A.M.G., Piatek, S., Andersen, O.M., Aronica, E., Willnow, T.E., Kaminska, B., Dabrowski, M.J. and Malik, A.R.
EMBO Reports 25 (5): 2278-2305. May 2024

Refined enterotyping reveals dysbiosis in global fecal metagenomes.
Keller, M.I., Nishijima, S., Podlesny, D., Kim, C.Y., Robbani, S.M., Schudoma, C., Fullam, A., Richter, J., Letunic, I., Akanni, W., Orakov, A., Schmidt, T.S., Marotta, F., Trebicka, J., Kuhn, M., Van Rossum, T. and Bork, P.
bioRxiv : 2024.08.13.607711v2. 14 August 2024

MRT-basierte automatische Nierensegmentierung und daraus abgeleitete Marker: Eine Auswertung der bevölkerungsweiten NAKO Gesundheitsstudie.
Kellner, E., Sekula, P., Lipovsek, J., Russe, M., Horbach, H., Schlett, C.L., Nauck, M., Völzke, H., Kroencke, T., Bette, S., Kauczor, H.U., Keil, T., Pischon, T., Heid, I.M., Peters, A., Niendorf, T., Lieb, W., Bamberg, F., Büchert, M, Reichardt, W., Reisert, M. and Köttgen, A.
Deutsches Arzteblatt International 121 : 284-90. 3 May 2024

Imaging markers derived from MRI-based automated kidney segmentation—an analysis of data from the German National Cohort (NAKO Gesundheitsstudie).
Kellner, E., Sekula, P., Lipovsek, J., Russe, M., Horbach, H., Schlett, C.L., Nauck, M., Völzke, H., Kröncke, T., Bette, S., Kauczor, H.U., Keil, T., Pischon, T., Heid, I.M., Peters, A., Niendorf, T., Lieb, W., Bamberg, F., Büchert, M., Reichardt, W., Reisert, M. and Köttgen, A.
Deutsches Arzteblatt International 121 (9): 284-290. 3 May 2024

Using routinely collected clinical data for circadian medicine: A review of opportunities and challenges.
Kervezee, L., Dashti, H.S., Pilz, L.K., Skarke, C. and Ruben, M.D.
PLOS Digital Health 3 (5): e0000511. 23 May 2024

Dysnatriämien - Konzepte und klinische Aufarbeitung [Dysnatremias - concepts and clinical work-up].
Kettritz, R.
Deutsche Medizinische Wochenschrift 149 (3): 86-92. February 2024

The association of a healthy lifestyle index and imaging-based body fat distribution with glycemic status and Type 2 diabetes in the Multi Ethnic Cohort: a cross-sectional analysis.
Klapp, R., Nimptsch, K., Pischon, T., Wilkens, L.R., Lim, U., Guillermo, C., Setiawan, V.W., Shepherd, J.A, Le Marchand, L. and Maskarinec, G.
European Journal of Clinical Nutrition 78 (3): 236-242. March 2024

Dynamic parametric MRI and deep learning: unveiling renal pathophysiology through accurate kidney size quantification.
Klein, T., Gladytz, T., Millward, J.M., Cantow, K., Hummel, L., Seeliger, E., Waiczies, S., Lippert, C. and Niendorf, T.
NMR in Biomedicine 37 (4): e5075. April 2024

β(2)-integrins control HIF1α activation in human neutrophils.
Kling, L., Eulenberg-Gustavus, C., Jerke, U., Rousselle, A., Eckardt, K.U., Schreiber, A. and Kettritz, R.
Frontiers in Immunology 15 : 1406967. 14 October 2024

Childhood trauma and somatic and mental illness in adulthood.
Klinger-König, J., Erhardt, A., Streit, F., Völker, M.P., Schulze, M.B, Keil, T., Fricke, J., Castell, S., Klett-Tammen, C.J., Pischon, T., Karch, A., Teismann, H., Michels, K.B., Greiser, K.H., Becher, H., Karrasch, S., Ahrens, W., Meinke-Franze, C., Schipf, S., Mikolajczyk, R., Führer, A., Brandes, B., Schmidt, B., Emmel, C., Leitzmann, M., Konzok, J., Peters, A., Obi, N., Brenner, H., Holleczek, B., Moreno Velásquez, I., Deckert, J., Baune, B.T., Rietschel, M., Berger, K. and Grabe, H.J.
Deutsches Arzteblatt International 121 (1): 1-8. 12 January 2024

Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling.
Kocere, A., Chiavacci, E., Soneson, C., Wells, H.H., Mendez-Acevedo, K.M., MacGowan, J.S., Jacobson, S.T., Hiltabidle, M.S., Raghunath, A., Shavit, J.A., Panákova, D., Williams, M.L.K., Robinson, M.D., Mosimann, C. and Burger, A.
bioRxiv : 2023.04.12.536513v4. 1 February 2024

International consensus on fasting terminology.
Koppold, D.A., Breinlinger, C., Hanslian, E., Kessler, C., Cramer, H., Khokhar, A.R., Peterson, C.M., Tinsley, G., Vernieri, C., Bloomer, R.J., Boschmann, M., Bragazzi, N.L., Brandhorst, S., Gabel, K., Goldhamer, A.C., Grajower, M.M., Harvie, M., Heilbronn, L., Horne, B.D., Karras, S.N., Langhorst, J., Lischka, E., Madeo, F., Mitchell, S.J., Papagiannopoulos-Vatopaidinos, I.E., Papagiannopoulou, M., Pijl, H., Ravussin, E., Ritzmann-Widderich, M., Varady, K., Adamidou, L., Chihaoui, M., de Cabo, R., Hassanein, M., Lessan, N., Longo, V., Manoogian, E.N.C., Mattson, M.P., Muhlestein, J.B., Panda, S., Papadopoulou, S.K., Rodopaios, N.E., Stange, R. and Michalsen, A.
Cell Metabolism 36 (8): 1779-1794. 6 August 2024

Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids.
Kranrod, J., Konkel, A., Valencia, R., Darwesh, A., Fischer, R., Schunck, W.H. and Seubert, J.M.
Journal of Biological Chemistry 300 (6): 107372. June 2024

Deep learning-based whole-brain B(1)(+)-mapping at 7T.
Krueger, F., Aigner, C.S., Lutz, M., Riemann, L.T., Degenhardt, K., Hadjikiriakos, K., Zimmermann, F.F., Hammernik, K., Schulz-Menger, J., Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 27 October 2024 (In Press)

Beyond hemoglobin: critical role of 2,3-bisphosphoglycerate mutase in kidney function and injury.
Kulow, V.A., Roegner, K., Labes, R., Kasim, M., Mathia, S., Czopek, C.S., Berndt, N., Becker, P.N., Ter-Avetisyan, G., Luft, F.C., Enghard, P., Hinze, C., Klocke, J., Eckardt, K.U., Schmidt-Ott, K.M., Persson, P.B., Rosenberger, C. and Fähling, M.
Acta Physiologica : e14242. 18 October 2024 (In Press)

UV light exposure versus vitamin D supplementation: a comparison of health benefits and vitamin D metabolism in a pig model.
Kühn, J., Brandsch, C., Bailer, A.C., Kiourtzidis, M., Hirche, F., Chen, C.Y., Markó, L., Bartolomaeus, T.U.P., Löber, U., Michel, S., Wensch-Dorendorf, M., Forslund-Startceva, S.K. and Stangl, G.I.
Journal of Nutritional Biochemistry 134 : 109746. December 2024

Protein intake and cancer: an umbrella review of systematic reviews for the evidence‑based guideline of the German Nutrition Society.
Kühn, T., Kalotai, N., Amini, A.M., Haardt, J., Lehmann, A., Schmidt, A., Buyken, A.E., Egert, S., Ellinger, S., Kroke, A., Lorkowski, S., Louis, S., Schulze, M.B., Schwingshackl, L., Siener, R., Stangl, G.I., Watzl, B., Zittermann, A. and Nimptsch, K.
European Journal of Nutrition 63 (5): 1471-1486. August 2024

Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange.
Kühne, L., Knöbl, P., Eller, K., Thaler, J., Sperr, W.R., Gleixner, K., Osterholt, T., Kaufeld, J., Menne, J., Buxhofer-Ausch, V., Mühlfeld, A., Seelow, E., Schreiber, A., Todorova, P., Cukoski, S., Jabs, W.J., Özcan, F., Gäckler, A., Schönfelder, K., Seibert, F.S., Westhoff, T., Schwenger, V., Eichenauer, D.A., Völker, L.A. and Brinkkoetter, P.T.
Blood 144 (14): 1486-1495. 3 October 2024

Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response.
Lafranchi, L., Spinner, A., Hornisch, M., Schlesinger, D., Luzon, C.N., Brinkenstråhle, L., Shao, R., Piazza, I. and Elsässer, S.J.
bioRxiv : 2024.12.08.627409. 9 December 2024

Long-read sequencing reveals extensive gut phageome structural variations driven by genetic exchange with bacterial hosts.
Lai, S., Wang, H., Bork, P., Chen, W.H. and Zhao, X.M.
Science Advances 10 (33): eadn3316. 16 August 2024

An exploratory research report on brain mineralization in postoperative delirium and cognitive decline.
Lammers-Lietz, F., Borchers, F., Feinkohl, I., Hetzer, S., Kanar, C., Konietschke, F., Lachmann, G., Chien, C., Spies, C., Winterer, G., Zaborszky, L., Zacharias, N. and Paul, F.
European Journal of Neuroscience 59 (10): 2646-2664. May 2024

Estimates of protection levels against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season: the IMMUNEBRIDGE project.
Lange, B., Jaeger, V.K., Harries, M., Rücker, V., Streeck, H., Blaschke, S., Petersmann, A., Toepfner, N., Nauck, M., Hassenstein, M.J., Dreier, M., von Holt, I., Budde, A., Bartz, A., Ortmann, J., Kurosinski, M.A., Berner, R., Borsche, M., Brandhorst, G., Brinkmann, M., Budde, K., Deckena, M., Engels, G., Fenzlaff, M., Härtel, C., Hovardovska, O., Katalinic, A., Kehl, K., Kohls, M., Krüger, S., Lieb, W., Meyer-Schlinkmann, K.M., Pischon, T., Rosenkranz, D., Rübsamen, N., Rupp, J., Schäfer, C., Schattschneider, M., Schlegtendal, A., Schlinkert, S., Schmidbauer, L., Schulze-Wundling, K., Störk, S., Tiemann, C., Völzke, H., Winter, T., Klein, C., Liese, J., Brinkmann, F., Ottensmeyer, P.F., Reese, J.P., Heuschmann, P. and Karch, A.
Infection 52 (1): 139-153. February 2024

Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progression.
Laschtowitz, A., Lindberg, E.L., Liebhoff, A.M., Liebig, L.A., Casar, C., Steinmann, S., Guillot, A., Xu, J., Schwinge, D., Trauner, M., Lohse, A.W., Bonn, S., Hübner, N. and Schramm, C.
JHEP Reports : 101267. 12 November 2024 (In Press)

Soluble ACE2 correlates with severe COVID-19 and can impair antibody responses.
Lebedin, M., Ratswohl, C., Garg, A., Schips, M., Vazquez Garcia, C., Spatt, L., Thibeault, C., Obermayer, B., Weiner, J., Moreno Velásquez, I., Gerhard, C., Stubbemann, P., Hanitsch, L.G., Pischon, T., Witzenrath, M., Sander, L.E., Kurth, F., Meyer-Hermann, M. and de la Rosa, K.
iScience 27 (3): 109330. 15 March 2024

Novel tryptophan hydroxylase inhibitor TPT-001 reverses PAH, vascular remodeling, and proliferative-proinflammatory gene expression.
Legchenko, E., Chouvarine, P., Qadri, F., Specker, E., Nazaré, M., Wesolowski, R., Matthes, S., Bader, M. and Hansmann, G.
JACC: Basic to Translational Science 9 (7): 890-902. July 2024

Blocking glycosphingolipid production alters autophagy in osteoclasts and improves myeloma bone disease.
Leng, H., Simon, A.K. and Horwood, N.J.
Autophagy 20 (4): 930-932. April 2024

Reliable off-resonance correction in high-field cardiac MRI using autonomous cardiac B0 segmentation with dual-modality deep neural networks.
Li, X., Huang, Y., Malagi, A., Yang, C.C., Yoosefian, G., Huang, L.T., Tang, E., Gao, C., Han, Fei, Bi, X., Ku, M.C., Yang, H.J. and Han, H.
Bioengineering 11 (3): 210. 23 February 2024

Converting PROMIS®-29 v2.0 profile data to SF-36 physical and mental component summary scores in patients with cardiovascular disorders.
Liegl, G., Fischer, F.H., Martin, C.N., Rönnefarth, M., Blumrich, A., Ahmadi, M., Boldt, L.H., Eckardt, K.U., Endres, M., Edelmann, F., Gerhardt, H., Grittner, U., Haghikia, A., Hübner, N., Landmesser, U., Leistner, D., Mai, K., Kollmus-Heege, J., Müller, D.N., Nolte, C.H., Piper, S.K., Schmidt-Ott, K.M., Pischon, T., Rattan, S., Rohrpasser-Napierkowski, Ira, Schönrath, K., Schulz-Menger, J., Schweizerhof, O., Spranger, J., Weber, J.E., Witzenrath, M., Schmidt, S. and Rose, M.
Health and Quality of Life Outcomes 22 (1): 64. 15 August 2024

Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Lisowski, P., Lickfett, S., Rybak-Wolf, A., Menacho, C., Le, S., Pentimalli, T.M., Notopoulou, S., Dykstra, W., Oehler, D., López-Calcerrada, S., Mlody, B., Otto, M., Wu, H., Richter, Y., Roth, P., Anand, R., Kulka, L.A.M., Meierhofer, D., Glazar, P., Legnini, I., Telugu, N.S., Hahn, T., Neuendorf, N., Miller, D.C., Böddrich, A., Polzin, A., Mayatepek, E., Diecke, S., Olzscha, H., Kirstein, J., Ugalde, C., Petrakis, S., Cambridge, S., Rajewsky, N., Kühn, R., Wanker, E.E., Priller, J., Metzger, J.J. and Prigione, A.
Nature Communications 15 (1): 7027. 22 August 2024

Quantification of multi-compartment flow with spectral diffusion MRI.
Liu, M.M., Dyke, J., Gladytz, T., Jasse, J., Bolger, I., Calle, S., Pavaluri, S., Crews, T., Seshan, S., Salvatore, S., Stillman, I., Muthukuma, T., Taouli, B., Farouk, S., Lewis, S. and Bane, O.
arXiv : 2408.06427. 12 August 2024

The role of glycocalyx diversity and thickness for nanoparticle internalization in M1-/M2-like macrophages.
Liu, Y., He, Y., Xu, H., Remmo, A., Wiekhorst, F., Heymann, F., Liu, H., Schellenberger, E., Häckel, A., Hauptmann, R., Taupitz, M., Shen, Y., Yilmaz, E.Y., Müller, D.N., Heidemann, L., Schmidt, R. and Savic, L.J.
Nano Letters 24 (49): 15607-15614. 11 December 2024

CD19-targeting CAR T cells protect from ANCA-induced acute kidney injury.
Lodka, D., Zschummel, M., Bunse, M., Rousselle, A., Sonnemann, J., Kettritz, R., Höpken, U.E. and Schreiber, A.
Annals of the Rheumatic Diseases 83 (4): 499-507. 12 March 2024

Characterization of anthracycline-induced cardiotoxicity by diffusion tensor magnetic resonance imaging.
Lohr, D., Thiele, A., Stahnke, M., Braun, V.M., Klopfleisch, R., Klein, O., Dresen, S., Landmesser, U., Foryst-Ludwig, A., Kintscher, U., Schreiber, L.M. and Beyhoff, N.
Basic Research in Cardiology 14 March 2024 (In Press)

Molecular characterization of nodose ganglia development reveals a novel population of Phox2b+ glial progenitors in mice.
Lowenstein, E.D., Misios, A., Buchert, S. and Ruffault, P.L.
Journal of Neuroscience 44 (28): e1441232024. 10 July 2024

Personal genetic-hypertension odyssey from phenotypes to genotypes and targets.
Luft, F.C.
Hypertension 81 (12): 2395-2406. December 2024

Calcineurin inhibition, cardiovascular consequences, vascular resistance, and potential responses.
Luft, F.C.
Acta Physiologica 240 (3): e14084. March 2024

Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.
Lyu, Y.X., Fu, Q., Wilczok, D., Ying, K., King, A., Antebi, A., Vojta, A., Stolzing, A., Moskalev, A., Georgievskaya, A., Maier, A.B., Olsen, A., Groth, A., Simon, A.K., Brunet, A., Jamil, A., Kulaga, A., Bhatti, A., Yaden, B., Pedersen, B.K., Schumacher, B., Djordjevic, B., Kennedy, B., Chen, C., Huang, C.Y., Correll, C.U., Murphy, C.T., Ewald, C.Y., Chen, D., Valenzano, D.R., Sołdacki, D., Erritzoe, D., Meyer, D., Sinclair, D.A., Chini, E.N., Teeling, E.C., Morgen, E., Verdin, E., Vernet, E., Pinilla, E., Fang, E.F., Bischof, E., Mercken, E.M., Finger, F., Kuipers, F., Pun, F.W., Gyülveszi, G., Civiletto, G., Zmudze, G., Blander, G., Pincus, H.A., McClure, J., Kirkland, J.L., Peyer, J., Justice, J.N., Vijg, J., Gruhn, J.R., McLaughlin, J., Mannick, J., Passos, J., Baur, J.A., Betts-LaCroix, J., Sedivy, J.M., Speakman, J.R., Shlain, J., von Maltzahn, J., Andreasson, K.I., Moody, K., Palikaras, K., Fortney, K., Niedernhofer, L.J., Rasmussen, L.J., Veenhoff, L.M., Melton, L., Ferrucci, L., Quarta, M., Koval, M., Marinova, M., Hamalainen, M., Unfried, M., Ringel, M.S., Filipovic, M., Topors, M., Mitin, N., Roy, N., Pintar, N., Barzilai, N., Binetti, P., Singh, P., Kohlhaas, P., Robbins, P.D., Rubin, P., Fedichev, P.O., Kamya, P., Muñoz-Canoves, P., de Cabo, R., Faragher, R.G.A., Konrad, R., Ripa, R., Mansukhani, R., Büttner, S., Wickström, S.A., Brunemeier, S., Jakimov, S., Luo, S., Rosenzweig-Lipson, S., Tsai, S.Y., Dimmeler, S., Rando, T.A., Peterson, T.R., Woods, T., Wyss-Coray, T., Finkel, T., Strauss, T., Gladyshev, V.N., Longo, V.D., Dwaraka, V.B., Gorbunova, V., Acosta-Rodríguez, V.A., Sorrentino, V., Sebastiano, V., Li, W., Suh, Y., Zhavoronkov, A., Scheibye-Knudsen, M. and Bakula, D.
Aging 16 (20): 12955-12976. 31 October 2024

Impact of training data composition on the generalizability of convolutional neural network aortic cross-section segmentation in four-dimensional magnetic resonance flow imaging.
Manini, C., Hüllebrand, M., Walczak, L., Nordmeyer, S., Jarmatz, L., Kuehne, T., Stern, H., Meierhofer, C., Harloff, A., Erley, J., Kelle, S., Bannas, P., Trauzeddel, R.F., Schulz-Menger, J. and Hennemuth, A.
Journal of Cardiovascular Magnetic Resonance 26 (2): 101081. 8 August 2024

A simulation-based phantom model for generating synthetic mitral valve image data-application to MRI acquisition planning.
Manini, C., Nemchyna, O., Akansel, S., Walczak, L., Tautz, L., Kolbitsch, C., Falk, V., Sündermann, S., Kühne, T., Schulz-Menger, J. and Hennemuth, A.
International Journal of Computer Assisted Radiology and Surgery 19 (3): 553-569. March 2024

Water conservation overrides osmotic diuresis during SGLT2 inhibition in patients with heart failure.
Marton, A., Saffari, S.E., Rauh, M., Sun, R.N., Nagel, A.M., Linz, P., Lim, T.T., Takase-Minegishi, K., Pajarillaga, A., Saw, S., Morisawa, N., Yam, W.K., Minegishi, S., Totman, J.J., Teo, S., Teo, L.L.Y., Ng, C.T., Kitada, K., Wild, J., Kovalik, J.P., Luft, F.C., Greasley, P.J., Chin, C.W.L., Sim, D.K.L. and Titze, J.
Journal of the American College of Cardiology 83 (15): 1386-1398. 16 April 2024

Hypertrophic obstructive cardiomyopathy-left ventricular outflow tract shapes and their hemodynamic influences applying CMR.
Mayr, T., Riazy, L., Trauzeddel, R.F., Bassenge, J.P., Wiesemann, S., Blaszczyk, E., Prothmann, M., Hadler, T., Schmitter, S. and Schulz-Menger, J.
International Journal of Cardiovascular Imaging 40 (11): 2371-2381. November 2024

Women in Autophagy: an initiative to promote gender parity in science.
McCabe, M., Boya, P., Chen, R.H., Chu, C.T., Colombo, M.I., Delgui, L., Eskelinen, E.L., Hamasaki, M., Hansen, M., He, C., Jäättelä, M., Kimchi, A., Kraft, C., Kundu, M., Melendez, A., Pattingre, S., Proikas-Cezanne, T., Sebti, S., Simon, A.K., Simonsen, A., Tooze, S.A., Vaccaro, M.I., Wang, X., White, E., Zhao, Y. and Cuervo, A.M.
Nature Cell Biology 26 (12): 2009-2012. December 2024

Kommentar zu den Leitlinien 2023 der ESC zum Management von Kardiomyopathien.
Meder, B., Eckardt, L., Falk, V., Klaassen, S., Klingenheben, T., Knebel, F., Schulze-Bahr, E. and Schulz-Menger, J.
Kardiologie 9 April 2024

External mechanical stability regulates hematoma vascularization in bone healing rather than endothelial YAP/TAZ mechanotransduction.
Mehl, J., Farahani, S.K., Brauer, E., Klaus-Bergmann, A., Thiele, T., Ellinghaus, A., Bartels-Klein, E., Koch, K., Schmidt-Bleek, K., Petersen, A., Gerhardt, H., Vogel, V. and Duda, G.N.
Advanced Science 11 (13): e2307050. 3 April 2024

Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease.
Menacho, C., Okawa, S., Alvarez-Merz, I., Wittich, A., Muñoz-Oreja, M., Lisowski, P., Pentimalli, T.M., Rybak-Wolf, A., Inak, G., Zakin, S., Thevandavakkam, M., Petersilie, L., Zaliani, A., Mlody, B., Seibt, A., Donnelly, J., Woleben, K., Fernandez-Checa, J., Herebian, D., Mayatepek, E., Rajewsky, N., Spinazzola, A., Schuelke, M., Perlstein, E., Rossi, A., Distelmaier, F., Holt, I.J., Pless, O., Rose, C., Del Sol, A. and Prigione, A.
bioRxiv : 2024.07.08.602501. 12 July 2024

Imlifidase – ein innovativer Therapieansatz in der Nephrologie [Imlifidase - an innovative treatment approach in nephrology].
Mestekemper, A.N. and Schreiber, A.
Nephrologie 19 : 248–251. July 2024

Likelihood of post-COVID condition in people with hybrid immunity; data from the German National Cohort (NAKO).
Mikolajczyk, R., Diexer, S., Klee, B., Pfrommer, L., Purschke, O., Fricke, J., Ahnert, P., Gabrysch, S., Gottschick, C., Bohn, B., Brenner, H., Buck, C., Castell, S., Gastell, S., Greiser, K.H., Harth, V., Heise, J.K., Holleczek, B., Kaaks, R., Keil, T., Krist, L., Leitzmann, M., Lieb, W., Meinke-Franze, Cl., Michels, K.B., Moreno Velásquez, I., Obi, N., Panreck, L., Peters, A., Pischon, T., Schikowski, T., Schmidt, B., Standl, M., Stang, A., Völzke, H., Weber, A., Zeeb, H. and Karch, A.
Journal of Infection 89 (2): 106206. August 2024

Sodium as an important regulator of immunometabolism.
Miyauchi, H., Geisberger, S., Luft, F.C., Wilck, N., Stegbauer, J., Wiig, H., Dechend, R., Jantsch, J., Kleinewietfeld, M., Kempa, S. and Mueller, D.N.
Hypertension 81 (3): 426-435. March 2024

Glycolysis–Wnt signaling axis tunes developmental timing of embryo segmentation.
Miyazawa, H., Rada, J., Sanchez, P.G.L., Esposito, E., Bunina, D., Girardot, C., Zaugg, J. and Aulehla, A.
bioRxiv : 2024.01.22.576629v2. 23 January 2024

The association of pre-operative biomarkers of endothelial dysfunction with the risk of post-operative neurocognitive disorders: results from the BioCog study.
Moazzen, S., Janke, J., Slooter, A.J.C., Winterer, G., Spies, C., Pischon, T. and Feinkohl, I.
BMC Anesthesiology 24 (1): 358. 8 October 2024

Disruption of basal CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.
Mobach, S, Bergkamp, N.D., Ma, Z, Haselager, M.V., Anbuhl, S.M., Jurriens, D, van den Bor, J., Wang, Z., Crudden, C., Roos, J.L., Perez Almeria, C.V., Boergonje, R.A., Lohse, M.J., Bosma, R., Eldering, E., Siderius, M., Wu, W., Spaargaren, M., Tonino, S.H., Kater, A.P., Smit, M.J. and Heukers, R.
bioRxiv : 2024.12.06.627249. 7 December 2024

Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia.
Mochmann, L.H., Treue, D., Bockmayr, M., Silva, P., Zasada, C., Mastrobuoni, G., Bayram, S., Forbes, M., Jurmeister, P., Liebig, S., Blau, O., Schleich, K., Splettstoesser, B., Nordmann, T.M., von der Heide, E.K., Isaakidis, K., Schulze, V., Busch, C., Siddiq, H., Schlee, C., Hester, S., Fransecky, L., Neumann, M., Kempa, S., Klauschen, F. and Baldus, C.D.
Cancer Gene Therapy 31 (9): 1344-1356. September 2024

The contractile machines of the heart.
Morano, I.
Advances in Experimental Medicine and Biology 1441 : 417-433. 18 June 2024

Do low levels of albuminuria predict mortality among young adults without major cardiovascular risk factors?
Moreno Velásquez, I. and Gigante, B.
European Journal of Preventive Cardiology 31 (17): 2056-2057. November 2024

The zebrafish heart harbors a thermogenic beige fat depot analog of human epicardial adipose tissue.
Morocho-Jaramillo, P.A., Kotlar-Goldaper, I., Zakarauskas-Seth, B.I., Purfürst, B., Filosa, A. and Sawamiphak, S.
Cell Reports 43 (3): 113955. 26 March 2024

A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea.
Mottaghinia, S., Stenzel, S., Tsangaras, K., Nikolaidis, N., Laue, M., Müller, K., Hölscher, H., Löber, U., McEwen, G.K., Donnellan, S.C., Rowe, K.C., Aplin, K.P., Goffinet, C. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 121 (6): e2220392121. 1 February 2024

Heterozygous missense variant in GLI2 impairs human endocrine pancreas development.
Mueller, L.M., Isaacson, A., Wilson, H., Salowka, A., Tay, I., Gong, M., Samir Elbarbary, N., Raile, K. and Spagnoli, F.M.
Nature Communications 15 (1): 2483. 20 March 2024

Natural proteome diversity links aneuploidy tolerance to protein turnover.
Muenzner, J., Trébulle, P., Agostini, F., Zauber, H., Messner, C.B., Steger, M., Kilian, C., Lau, K., Barthel, N., Lehmann, A., Textoris-Taube, K., Caudal, E., Egger, A.S., Amari, F., De Chiara, M., Demichev, V., Gossmann, T.I., Mülleder, M., Liti, G., Schacherer, J., Selbach, M., Berman, J. and Ralser, M.
Nature 630 (8015): 149-157. 6 June 2024

SPINEPS-automatic whole spine segmentation of T2-weighted MR images using a two-phase approach to multi-class semantic and instance segmentation.
Möller, H., Graf, R., Schmitt, J., Keinert, B., Schön, H., Atad, M., Sekuboyina, A., Streckenbach, F., Kofler, F., Kroencke, T., Bette, S., Willich, S.N., Keil, T., Niendorf, T., Pischon, T., Endemann, B., Menze, B., Rueckert, D. and Kirschke, J.S.
European Radiology 29 October 2024 (In Press)

Inter-site comparability of 4D flow cardiovascular magnetic resonance measurements in healthy traveling volunteers -- a multi-site and multi-magnetic field strength study.
Müller, M., Daud, E., Langer, G., Gröschel, J., Viezzer, D., Hadler, T., Jin, N., Giese, D., Schmitter, S., Schulz-Menger, J. and Trauzeddel, R.F.
Frontiers in Cardiovascular Medicine 11 : 1456814. 8 November 2024

High-throughput anaerobic screening for identifying compounds acting against gut bacteria in monocultures or communities.
Müller, P., de la Cuesta-Zuluaga, J., Kuhn, M., Baghai Arassi, M., Treis, T., Blasche, S., Zimmermann, M., Bork, P., Patil, K.R., Typas, A., Garcia-Santamarina, S. and Maier, L.
Nature Protocols 19 (3): 668-699. March 2024

Fluorescent tools for the imaging of dopamine D2-like receptors.
Nagl, M., Moennich, D., Rosier, N., Schihada, H., Sirbu, A., Konar, N., Reyes-Resina, I., Navarro, G., Franco, R., Kolb, P., Annibale, P. and Pockes, S.
ChemBioChem 25 (2): e202300659. 15 January 2024

Socioeconomic characteristics and the home food environment are associated with feeding healthful and discretionary foods in the first year of life in the Pregnancy Eating Attributes Study.
Nansel, T.R., Lipsky, L.M., Schwedhelm, C., Faith, M.S. and Siega-Riz, A.M.
Journal of the Academy of Nutrition and Dietetics 2024 (In Press)

μCT imaging of a multi-organ vascular fingerprint in rats.
Napieczyńska, H., Kedziora, S.M., Haase, N., Muller, D.N., Heuser, A., Dechend, R. and Kraeker, K.
PLoS ONE 19 (10): e0308601. 14 October 2024

ATF4 orchestrates IL-1α-induced senescence in adult neural stem cells.
Neumann, S., Thelin, E.P., Sankavaram, S.R., Persson, S., Fonseca, L., Moruzzi, N., Iacobaeus, E., Bergsland, M., Popova, E., Bader, M., Svensson, M., Espinosa, A., Covacu, R. and Brundin, L.
bioRxiv : 2024.03.17.585394. 17 March 2024

MRI of kidney size matters.
Niendorf, T., Gladytz, T., Cantow, K., Klein, T., Tasbihi, E., Velasquez Vides, J.R., Zhao, K., Millward, J.M., Waiczies, S. and Seeliger, E.
Magnetic Resonance Materials in Physics, Biology and Medicine 37 (4): 651-669. August 2024

Lebenserwartung.
Nimptsch, K. and Pischon, T.
In: Adipositas: Ätiologie, Folgekrankheiten, Diagnostik, Therapie. Springer, Berlin, Heidelberg, 351-358. ISBN 978-3-662-58894-9 27 July 2024

Pregnancy associated plasma protein-A2 (PAPP-A2) and stanniocalcin-2 (STC2) but not PAPP-A are associated with circulating total IGF-1 in a human adult population.
Nimptsch, K., Aydin, E.E., Chavarria, R.F.R., Janke, J., Poy, M.N., Oxvig, C., Steinbrecher, A. and Pischon, T.
Scientific Reports 14 (1): 1770. 20 January 2024

Epidemiology of obesity.
Nimptsch, K. and Pischon, T.
In: Handbook of eating disorders and obesity. Springer, Berlin, Heidelberg, Germany, 425-430. ISBN 978-3-662-67662-2 25 April 2024

Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations.
Nishijima, S., Stankevic, E., Aasmets, O., Schmidt, T.S.B., Nagata, N., Keller, M.I., Ferretti, P., Juel, H.B., Fullam, A., Robbani, S.M., Schudoma, C., Hansen, J.K., Holm, L.A., Israelsen, M., Schierwagen, R., Torp, N., Telzerow, A., Hercog, R., Kandels, S., Hazenbrink, D.H.M., Arumugam, M., Bendtsen, F., Brøns, C., Fonvig, C.E., Holm, J.C., Nielsen, T., Pedersen, J.S., Thiele, M.S., Trebicka, J., Org, E., Krag, A., Hansen, T., Kuhn, M. and Bork, P.
Cell 13 November 2024 (In Press)

Single-stranded HDR templates with truncated Cas12a binding sequences improve knock-in efficiencies in primary human T cells.
Nitulescu, A.M., Du, W., Glaser, V., Kath, J., Greensmith, R., Mikkelsen, N.S., Stein, M., Bak, R., Kaminski, M.M. and Wagner, D.L.
bioRxiv : 2024.09.11.608426. 11 September 2024

Senescent syncytiotrophoblast secretion during early onset preeclampsia.
Nonn, O., Debnath, O., Valdes, D.S., Sallinger, K., Secener, A.K., Fischer, C., Tiesmeyer, S., Nimo, J., Kuenzer, T., Ulrich, J., Maxian, T., Knöfler, M., Karau, P., Bartolomaeus, H., Kroneis, T., Frolova, A., Neuper, L., Haase, N., Malt, A., Müller-Bötticher, N., Kräker, K., Kedziora, S., Forstner, D., Eils, R., Schmidt-Ullrich, R., Haider, S., Verlohren, S., Stern, C., Sugulle, M., Jones, S., Thilaganathan, B., Kaitu'u-Lino, T.J., Tong, S., Huppertz, B., El-Heliebi, A., Staff, A.C., Coscia, F., Müller, D.N., Dechend, R., Gauster, M., Ishaque, N. and Herse, F.
Hypertension 23 October 2024 (In Press)

ACE2 knockout mice are resistant to high-fat diet-induced obesity in an age-dependent manner.
Nunes-Souza, V., Alenina, N., Qadri, F., Mosienko, V., Santos, R.A.S., Bader, M. and Rabelo, L.A.
International Journal of Molecular Sciences 25 (17): 9515. 1 September 2024

Simulating rigid head motion artifacts on brain magnitude MRI data-Outcome on image quality and segmentation of the cerebral cortex.
Olsson, H., Millward, J.M., Starke, L., Gladytz, T., Klein, T., Fehr, J., Lai, W.C., Lippert, C., Niendorf, T. and Waiczies, S.
PLoS ONE 19 (4): e0301132. 16 April 2024

Tripartite interactions of PKA catalytic subunit and C-terminal domains of cardiac Ca(2+) channel may modulate its β-adrenergic regulation.
Oz, S., Keren-Raifman, T., Sharon, T., Subramaniam, S., Pallien, T., Katz, M., Tsemakhovich, V., Sholokh, A., Watad, B., Tripathy, D.R., Sasson, G., Chomsky-Hecht, O., Vysochek, L., Schulz-Christian, M., Fecher-Trost, C., Zühlke, K., Bertinetti, D., Herberg, F.W., Flockerzi, V., Hirsch, J.A., Klussmann, E., Weiss, S. and Dascal, N.
BMC Biology 22 (1): 276. 28 November 2024

Mechanosensitive PIEZO2 channels shape coronary artery development.
Pampols-Perez, M., Fürst, C., Sánchez-Carranza, O., Cano, E., Raimundo, S., Lindberg, E.L., Taube, M., Heuser, A., Sporbert, A., Hübner, N., Gerhardt, H., Lewin, G.R. and Hammes, A.
bioRxiv : 2024.07.08.602502. 11 July 2024

Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes.
Pekayvaz, K., Losert, C., Knottenberg, V., Gold, C., van Blokland, I.V., Oelen, R., Groot, H.E., Benjamins, J.W., Brambs, S., Kaiser, R., Gottschlich, A., Hoffmann, G.V., Eivers, L., Martinez-Navarro, A., Bruns, N., Stiller, S., Akgöl, S., Yue, K., Polewka, V., Escaig, R., Joppich, M., Janjic, A., Popp, O., Kobold, S., Petzold, T., Zimmer, R., Enard, W., Saar, K., Mertins, P., Huebner, N., van der Harst, P., Franke, L.H., van der Wijst, M.G.P., Massberg, S., Heinig, M., Nicolai, L. and Stark, K.
Nature Medicine 30 (6): 1696-1710. June 2024

Challenges and opportunities in the clinical translation of high-resolution spatial transcriptomics.
Pentimalli, T.M., Karaiskos, N. and Rajewsky, N.
Annual Review of Pathology : Mechanisms of Disease 30 October 2024 (In Press)

Human genetics of defects of situs.
Perrot, A. and Rickert-Sperling, S.
Advances in Experimental Medicine and Biology 1441 (1411): 705-717. 18 June 2024

Human genetics of ventricular septal defect.
Perrot, A. and Rickert-Sperling, S.
Advances in Experimental Medicine and Biology 1441 (1141): 505-534. 18 June 2024

In preprints: keeping endothelial cell specification and vascular development in check.
Petzold, T. and Gerhardt, H.
Development 151 (18): dev204338. September 2024

Pre-diagnostic circulating resistin concentrations and mortality among individuals with colorectal cancer: results from the European Prospective Investigation into Cancer and Nutrition study.
Pham, T.T., Nimptsch, K., Aleksandrova, K., Jenab, M., Fedirko, V., Wu, K., Eriksen, A.K., Tjønneland, A., Severi, G., Rothwell, J., Kaaks, R., Katzke, V., Catalano, A., Agnoli, C., Masala, G., De Magistris, M.S., Tumino, R., Vermeulen, R., Aizpurua, A., Trobajo-Sanmartín, C., Chirlaque, M.D., Sánchez, M.J., Lu, S.S.M., Cross, A.J., Christakoudi, S., Weiderpass, E. and Pischon, T.
International Journal of Cancer 154 (9): 1596-1606. 1 May 2024

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling.
Piletic, K., Kayvanjoo, A.H., Richter, F.C., Borsa, M., Lechuga-Vieco, A.V., Popp, O., Grenet, S., Ko, J.K.L., Zec, K., Kyriazi, M., Koneva, L., Sansom, S., Mertins, P., Powrie, F., Alsaleh, G. and Simon, A.K.
bioRxiv : 2024.09.17.613382. 17 September 2024

Identifying chromosome movement patterns during meiosis using ChroMo.
Pinto-Cruz, J., Correas, M., Mendoza-Madrigal, R., León-Periñán, D. and Fernández-Álvarez, A.
Methods in Molecular Biology 2818 : 271-288. 2024

Intergenic risk variant rs56258221 skews the fate of naive CD4(+) T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis.
Poch, T., Bahn, J., Casar, C., Krause, J., Evangelakos, I., Gilladi, H., Kunzmann, L.K., Laschtowitz, A., Iuso, N., Schäfer, A.M., Liebig, L.A., Steinmann, S., Sebode, M., Folseraas, T., Engesæter, L.K., Karlsen, T.H., Franke, A., Hubner, N., Schlein, C., Galun, E., Huber, S., Lohse, A.W., Gagliani, N., Schwinge, D. and Schramm, C.
Cell Reports Medicine 5 (7): 101620. 16 July 2024

Hif-2α programs oxygen chemosensitivity in chromaffin cells.
Prange-Barczynska, M., Jones, H.A., Sugimoto, Y., Cheng, X., Lima, J.D., Ratnayaka, I., Douglas, G., Buckler, K.J., Ratcliffe, P.J., Keeley, T.P. and Bishop, T.
Journal of Clinical Investigation 134 (18): e174661. 6 August 2024

Scalable image-based visualization and alignment of spatial transcriptomics datasets.
Preibisch, S., Innerberger, M., León-Periñán, D., Karaiskos, N. and Rajewsky, N.
bioRxiv : 2021.12.07.471629v3. 7 October 2024

IA-PACS-CFS: a double-blinded, randomized, sham-controlled, exploratory trial of immunoadsorption in patients with chronic fatigue syndrome (CFS) including patients with post-acute COVID-19 CFS (PACS-CFS).
Preßler, H., Machule, M.L., Ufer, F., Bünger, I., Li, L.Y., Buchholz, E., Werner, C., Beraha, E., Wagner, F., Metz, M., Burock, S., Bruckert, L., Franke, C., Wilck, N., Krüger, A., Reshetnik, A., Eckardt, K.U., Endres, M. and Prüss, H.
Trials 25 (1): 172. 7 March 2024

Urinary CD4(+) T cells predict renal relapse in ANCA-associated vasculitis: results of the PRE-FLARED study.
Prskalo, L., Skopnik, C.M., Goerlich, N., Freund, P., Wagner, L., Grothgar, E., Mirkheshti, P., Klocke, J., Sonnemann, J., Metzke, D., Schneider, U., Hiepe, F., Eckardt, K.U., Salama, A.D., Bieringer, M., Schreiber, A. and Enghard, P.
Journal of the American Society of Nephrology 35 (4): 483-494. April 2024

Oropharyngeal microbial ecosystem perturbations influence the risk for acute respiratory infections in common variable immunodeficiency.
Pulvirenti, F., Giufrè, M., Pentimalli, T.M., Camilli, R., Milito, C., Villa, A., Sculco, E., Cerquetti, M., Pantosti, A. and Quinti, I.
Frontiers in Immunology 15 : 1371118. 30 May 2024

Comparison of Xrn1 and Rat1 5′ → 3′ exoribonucleases in budding yeast supports the specific role of Xrn1 in cotranslational mRNA decay.
Pérez-Ortín, J.E., Jordán-Pla, A., Zhang, Y., Moreno-García, J., Bassot, C., Barba-Aliaga, M., de Campos-Mata, L., Choder, M., Díez, J., Piazza, I., Pelechano, V. and García-Martínez, J.
Yeast 41 (7): 458-472. July 2024

Delegation of the primary responsibility for MRI informed consent to technical assistants—findings from the NAKO health study.
Quinsten, A.S., Haubold, J., Kröncke, T., Friedrich, L., Pischon, T., Niendorf, T., Forsting, M., Hosten, N., Völzke, H., Bamberg, F., Schlett, C.L., Kauczor, H.U., Brandelik, S. and Theysohn, J.
Deutsches Ärzteblatt international 121 (7): 228-229. 5 April 2024

Selection on synonymous sites: the unwanted transcript hypothesis.
Radrizzani, S., Kudla, G., Izsvák, Z. and Hurst, L.D.
Nature Reviews Genetics 25 (6): 431-448. June 2024

Helmet radio frequency phased array applicators enhance thermal magnetic resonance of brain tumors.
Rahimi, F., Nurzed, B., Eigentler, T.W., Berangi, M., Oberacker, E., Kuehne, A., Ghadjar, P., Millward, J.M., Schuhmann, R. and Niendorf, T.
Bioengineering 11 (7): 733. July 2024

Multilayer nanocarrier for the codelivery of interferons: a promising strategy for biocompatible and long-acting antiviral treatment.
Ramos, T.I., Villacis-Aguirre, C.A., Sandoval, F.S., Martin-Solano, S., Manrique-Suárez, V., Rodríguez, H., Santiago-Padilla, L., Debut, A., Gómez-Gaete, C., Arias, M.T., Montesino, R., Lamazares, E., Cabezas, I., Hugues, F., Parra, N.C., Altamirano, C., Ramos, O.S., Santiago-Vispo, N. and Toledo, J.R.
Pharmaceutics 16 (11): 1349. 22 October 2024

Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort.
Reichmann, R., Nimptsch, K., Pischon, T., Gunter, M.J., Jenab, M., Eriksen, A.K., Tjonneland, A., Janke, J., Katzke, V., Kaaks, R., Schulze, M.B., Eichelmann, F., Masala, G., Sieri, S., Pasanisi, F., Tumino, R., Giraudo, M.T., Rothwell, J., Severi, G., Jakszyn, P., Sanchez-Perez, M.J., Amiano, P., Colorado-Yohar, S.M., Guevara, M., van Guelpen, B., Aglago, E.K., Heath, A.K., Smith-Byrne, K., Weiderpass, E. and Aleksandrova, K.
International Journal of Cancer 7 November 2024 (In Press)

Biomarker signatures associated with ageing free of major chronic diseases: results from a population-based sample of the EPIC-Potsdam cohort.
Reichmann, R., Schulze, M.B., Pischon, T., Weikert, C. and Aleksandrova, K.
Age and Ageing 53 (Supplement_2): ii60-ii69. May 2024

Protease-activated receptor-1 IgG autoantibodies in patients with COVID-19.
Reinshagen, L., Nageswaran, V., Heidecke, H., Schulze-Forster, K., Wilde, A.C.B., Ramezani Rad, P., Poller, W., Asmus, E., Simmons, S., Kuebler, W.M., Witzenrath, M., Markó, L., Jakobs, K., Puccini, M., Leistner, D.M., Rauch-Kröhnert, U., Kränkel, N., Forslund, S.K., Landmesser, U., Müller, D.N. and Haghikia, A.
Thrombosis and Haemostasis 124 (12): 1164-1166. December 2024

USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
Reissland, M., Hartmann, O., Tauch, S., Bugter, J.M., Prieto-Garcia, C., Schulte, C., Loebbert, S., Solvie, D., Bitman-Lotan, E., Narain, A., Jacomin, A.C., Schuelein-Voelk, C., Fuss, C.T., Pahor, N., Ade, C., Buck, V., Potente, M., Li, V., Beliu, G., Wiegering, A., Grossmann, T., Eilers, M., Wolf, E., Maric, H., Rosenfeldt, M., Maurice, M.M., Dikic, I., Gallant, P., Orian, A. and Diefenbacher, M.E.
Oncogene 43 (50): 3645-3659. 2 December 2024

PITX2 deficiency leads to atrial mitochondrial dysfunction.
Reyat, J.S., Sommerfeld, L.C., O'Reilly, M., Cardoso, V.R., Thiemann, E., Khan, A.O., O'Shea, C., Harder, S., Müller, C., Barlow, J., Stapley, R.J., Chua, W., Kabir, S.N., Grech, O., Hummel, O., Hübner, N., Kääb, S., Mont, Ll., Hatem, S.N., Winters, J., Zeemering, S., Morgan, N.V., Rayes, J., Gehmlich, K., Stoll, M., Brand, T., Schweizer, M., Piasecki, A., Schotten, U., Gkoutos, G.V., Lorenz, K., Cuello, F., Kirchhof, P. and Fabritz, L.
Cardiovascular Research 120 (15): 1907-1923. November 2024

Serotonin drives aggression and social behaviours of laboratory mice in a semi-natural environment.
Rivalan, M., Alonso, L., Mosienko, V., Bey, P., Hyde, A., Bader, M., Winter, Y. and Alenina, N.
Frontiers in Behavioral Neuroscience 18 18 September 2024

Renin is essential for angiotensin II formation in the brain.
Rodrigues, A.F., Domenig, O., Garrelds, I.M., Danser, J.A.H., Alenina, N., Poglitsch, M. and Bader, M.
Journal of the American Heart Association 13 (22): e034209. 19 November 2024

Angiotensin-(1-12): does it exist? A critical evaluation in humans, rats, and mice.
Rodrigues, A.F., Domenig, O., Poglitsch, M., Bader, M. and Danser, A.H.J.
Hypertension 81 (8): 1776-1784. August 2024

Functional and evolutionary significance of unknown genes from uncultivated taxa.
Rodríguez Del Río, Á., Giner-Lamia, J., Cantalapiedra, C.P., Botas, J., Deng, Z., Hernández-Plaza, A., Munar-Palmer, M., Santamaría-Hernando, S., Rodríguez-Herva, J.J., Ruscheweyh, H.J., Paoli, L., Schmidt, T.S.B., Sunagawa, S., Bork, P., López-Solanilla, E., Coelho, L.P. and Huerta-Cepas, J.
Nature 626 (7998): 377-384. 8 February 2024

Shedding light on the D1‐like receptors: a fluorescence‐based toolbox for visualization of the D1 and D5 receptors.
Rosier, N., Moennich, D., Nagl, M., Schihada, H., Sirbu, A., Konar, N., Reyes-Resina, I., Navarro, G., Franco, R., Kolb, P., Annibale, P. and Pockes, S.
ChemBioChem 25 (2): e202300658. 15 January 2024

Sociality shapes mitochondrial adaptations supporting hypoxia tolerance.
Rossi, A., Ruwolt, M., Kakouri, P., Kosten, T., Kunz, S., Puchkov, D., Reznick, J., Purfürst, B., Omerbašić, D., Méndez Aranda, D., Carai, G., Mastrobuoni, G., Hart, D.W., Carraro, M., Tommasin, L., Bennett, N.C., Bégay, V., Faelber, K., Daumke, O., Bernardi, P., Park, T.J., Kempa, S., Liu, F. and Lewin, G.R.
bioRxiv : 2024.09.30.615914. 2 October 2024

Does age protect against loss of tonotopy after acute deafness in adulthood?
Rosskothen-Kuhl, N., Green, S. and Jakob, T.F.
bioRxiv : 2024.05.03.592347. 3 May 2024

Normal male fertility in a mouse model of KPNA2 deficiency.
Rother, F., Abu Hweidi, D., Hartmann, E. and Bader, M.
PLoS ONE 19 (10): e0304189. 18 October 2024

Karyopherin α2 is a maternal effect gene required for early embryonic development and female fertility in mice.
Rother, F., Depping, R., Popova, E., Huegel, S., Heiler, A., Hartmann, E. and Bader, M.
FASEB Journal 38 (8): e23623. 30 April 2024

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T., Meyer, K., Roske, Y., Uyar, B., Akalin, A., Imami, K., Ishihama, Y., Daumke, O. and Selbach, M.
Nature Communications 15 (1): 3146. 11 April 2024

Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts.
Ruiz-Orera, J., Miller, D.C., Greiner, J., Genehr, C., Grammatikaki, A., Blachut, S., Mbebi, J., Patone, G., Myronova, A., Adami, E., Dewani, N., Liang, N., Hummel, O., Mücke, M.B., Hildebrandt, T.B., Fritsch, G., Schrade, L., Zimmermann, W.H., Kondova, I., Diecke, S., van Heesch, S. and Hübner, N.
Nature Cardiovascular Research 3 (10): 1217-1235. October 2024

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics.
Sakenova, N., Cacace, E., Orakov, A., Huber, F., Varik, V., Kritikos, G., Michiels, J., Bork, P., Cossart, P., Goemans, C.V. and Typas, A.
Nature Microbiology 2 December 2024 (In Press)

Targeting HFpEF: unlocking the potential of glucagon receptor blockade.
Santiago Padilla, L. and Schiattarella, G.G.
Circulation Research 135 (5): 629-631. 16 August 2024

Discovery of antimicrobial peptides in the global microbiome with machine learning.
Santos-Júnior, C.D., Torres, M.D.T., Duan, Y., Rodríguez Del Río, Á., Schmidt, T.S.B., Chong, H., Fullam, A., Kuhn, M., Zhu, C., Houseman, A., Somborski, J., Vines, A., Zhao, X.M., Bork, P., Huerta-Cepas, J., de la Fuente-Nunez, C. and Coelho, L.P.
Cell 187 (14): 3761-3778. 11 July 2024

Mapping DHPS evolvability: identification of novel evolutionarily critical sub-structure through evolutionary and structural analyses of DHPS.
Sanyal, D., Shivram, A., Banerjee, S., Uversky, V.N., Chivukula, A., Chattopadhyay, K. and Chowdhury, S.
bioRxiv : 2024.10.16.618629. 18 October 2024

Regimens and response assessment in minimally invasive image-guided therapies for vascular malformations: insights from a large cohort study at a tertiary-care hospital.
Savic, G.D., Torsello, G.F., Frisch, A., Wieners, G., Fehrenbach, U., Auer, T.A., Lüdemann, W.M., Gebauer, B. and Savic, L.J.
Life 14 (10): 1270. 5 October 2024

Twisted-plywood-like tissue formation in vitro. Does curvature do the twist?
Schamberger, B., Ehrig, S., Dechat, T., Spitzer, S., Bidan, C.M., Fratzl, P., Dunlop, J.W.C. and Roschger, A.
PNAS Nexus 3 (4): pgae121. April 2024

Decision-tree models indicative of microvascular invasion on MRI predict survival in patients with hepatocellular carcinoma following tumor ablation.
Schmidt, R., Hamm, C.A., Rueger, C., Xu, H., He, Y., Gottwald, L.A., Gebauer, B. and Savic, L.J.
Journal of Hepatocellular Carcinoma 11 : 1279-1293. 3 July 2024

SPIRE: a Searchable, Planetary-scale mIcrobiome REsource.
Schmidt, T.S.B., Fullam, A., Ferretti, P., Orakov, A., Maistrenko, O.M., Ruscheweyh, H.J., Letunic, I., Duan, Y., Van Rossum, T., Sunagawa, S., Mende, D.R., Finn, R.D., Kuhn, M., Pedro Coelho, L. and Bork, P.
Nucleic Acids Research 52 (D1): D777-D783. 5 January 2024

Host weight, seasonality and anthropogenic factors contribute to parasite community differences between urban and rural foxes.
Scholz, C., Jarquín-Díaz, V.H., Planillo, A., Radchuk, V., Scherer, C., Schulze, C., Ortmann, S., Kramer-Schadt, S. and Heitlinger, E.
Science of the Total Environment 936 : 173355. August 2024

Open-ST: high-resolution spatial transcriptomics in 3D.
Schott, M., León-Periñán, D., Splendiani, E., Strenger, L., Licha, J.R., Pentimalli, T.M., Schallenberg, S., Alles, J., Samut Tagliaferro, S., Boltengagen, A., Ehrig, S., Abbiati, S., Dommerich, S., Pagani, M., Ferretti, E., Macino, G., Karaiskos, N. and Rajewsky, N.
Cell 187 (15): 3953-3972.e26. 25 July 2024

Protein intake and type 2 diabetes mellitus: an umbrella review of systematic reviews for the evidence-based guideline for protein intake of the German Nutrition Society.
Schulze, M.B., Haardt, J., Amini, A.M., Kalotai, N., Lehmann, A., Schmidt, A., Buyken, A.E., Egert, S., Ellinger, S., Kroke, A., Kühn, T., Louis, S., Nimptsch, K., Schwingshackl, L., Siener, R., Zittermann, A., Watzl, B. and Lorkowski, S.
European Journal of Nutrition 63 (1): 33-50. February 2024

ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling.
Scoyni, F., Sitnikova, V., Giudice, L., Korhonen, P., Trevisan, D.M., Hernandez de Sande, A., Gomez-Budia, M., Giniatullina, R., Ugidos, I.F., Dhungana, H., Pistono, C., Korvenlaita, N., Välimäki, N.N., Kangas, S.M., Hiltunen, A.E., Gribchenko, E., Kaikkonen-Määttä, M.U., Koistinaho, J., Ylä-Herttuala, S., Hinttala, R., Venø, M.T., Su, J., Stoffel, M., Schaefer, A., Rajewsky, N., Kjems, J., LaPierre, M.P., Piwecka, M., Jolkkonen, J., Giniatullin, R., Hansen, T.B. and Malm, T.
Cell Reports 43 (3): 113862. 26 March 2024

Impairment of the adrenergic reserve associated with exercise intolerance in a murine model of heart failure with preserved ejection fraction.
Semmler, L., Jeising, T., Huettemeister, J., Bathe-Peters, M., Georgoula, K., Roshanbin, R., Sander, P., Fu, S., Bode, D., Hohendanner, F., Pieske, B., Annibale, P., Schiattarella, G.G., Oeing, C.U. and Heinzel, F.R.
Acta Physiologica 240 (4): e14124. April 2024

Advancing research and treatment: an overview of clinical trials in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and future perspectives.
Seton, K.A., Espejo-Oltra, J.A., Giménez-Orenga, K., Haagmans, R., Ramadan, D.J. and Mehlsen, J.
Journal of Clinical Medicine 13 (2): 325. 6 January 2024

Medium term (> 12 months) outcomes after laparoscopic hiatal hernia repair without conventional fundoplication using PH4B‑mesh implant (Phasix™) in 176 reflux patients: experience and technique.
Siemssen, B., Dahlke, P.M., Behrens, F., Hentschel, F. and Ibach, M.J.
Hernia 28 (5): 1641-1647. October 2024

Cell swelling enhances ligand-driven β-adrenergic signaling.
Sirbu, A., Bathe-Peters, M., Kumar, J.L.M, Inoue, A., Lohse, M.J. and Annibale, P.
Nature Communications 15 (1): 7822. 7 September 2024

Cell swelling enhances canonical β-adrenergic signaling.
Sirbu, A., Bathe-Peters, M., Kumar, J.L.M., Inoue, A., Lohse, M. and Annibale, P.
bioRxiv : 2023.06.23.544496v5. 23 August 2024

Angiotensin-(1-5) is a potent endogenous angiotensin AT(2)-receptor agonist.
Souza-Silva, I.M., Peluso, A.A., Elsaafien, K., Nazarova, A.L., Assersen, K.B., Rodrigues-Ribeiro, L., Mohammed, M., Rodrigues, A.F., Nawrocki, A., Johansen, L.A., Jensen, P., de Kloet, A.D., Krause, E.G., DelBorgo, M., Maslov, I., Widdop, R.E., Santos, R.A., Bader, M., Larsen, M.R., Verano-Braga, T., Katritch, V., Sumners, C. and Steckelings, U.M.
bioRxiv : 2024.04.05.588367v2. 18 April 2024

Telemonitoring for chronic heart failure: narrative review of the 20-year journey from concept to standard care in Germany.
Spethmann, S., Hindricks, G., Koehler, K., Stoerk, S., Angermann, C.E., Böhm, M., Assmus, B., Winkler, S., Mökel, M., Mittermaier, M., Lelgemann, M., Reuter, D., Bosch, R., Albrecht, A., von Haehling, S., Helms, T.M., Sack, S., Bekfani, T., Gröschel, J.W., Koehler, M., Melzer, C., Wintrich, J., Zippel-Schultz, B., Ertl, G., Vogelmeier, C., Dagres, N., Zernikow, J. and Koehler, F.
Journal of medical Internet research 26 : e63391. 4 December 2024

Hypertensive disorders of pregnancy and cardiovascular disease risk.
Staff, A.C., Dechend, R. and Jacobsen, D.P.
In: Manual of Cardiovascular Disease in Women. Springer Nature Switzerland, Cham, Switzerland, 119-141. ISBN 978-3-031-65952-2 28 September 2024

Hypertensive disorders of pregnancy and long-term maternal cardiovascular risk: bridging epidemiological knowledge into personalized postpartum care and follow-up.
Staff, A.C., Costa, M.L., Dechend, R., Jacobsen, D.P. and Sugulle, M.
Pregnancy Hypertension 36 : 101127. June 2024

The challenges of research data management in cardiovascular science: a DGK and DZHK position paper-executive summary.
Steffens, S., Schröder, K., Krüger, M., Maack, C., Streckfuss-Bömeke, K., Backs, J., Backofen, R., Baeßler, B., Devaux, Y., Gilsbach, R., Heijman, J., Knaus, J., Kramann, R., Linz, D., Lister, A.L., Maatz, H., Maegdefessel, L., Mayr, M., Meder, B., Nussbeck, S.Y., Rog-Zielinska, E.A., Schulz, M.H., Sickmann, A., Yigit, G. and Kohl, P.
Clinical Research in Cardiology 113 (5): 672-679. May 2024

Cryosectioning-enabled super-resolution microscopy for studying nuclear architecture at the single protein level.
Stein, J., Ericsson, M., Nofal, M., Magni, L., Aufmkolk, S., McMillan, R.B., Breimann, L., Herlihy, C.P., Lee, S.D., Willemin, A., Wohlmann, J., Arguedas-Jimenez, L., Yin, P., Pombo, A., Church, G.M. and Wu, C.T.
bioRxiv : 2024.02.05.576943. 5 February 2024

Differences in anthropometric measures based on sex, age, and health status: findings from the German National Cohort (NAKO).
Stein, M.J., Fischer, B., Bohmann, P., Ahrens, W., Berger, K., Brenner, H., Günther, K., Harth, V., Heise, J.K., Karch, A., Klett-Tammen, C.J., Koch-Gallenkamp, L., Krist, L., Lieb, W., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Nimptsch, K., Obi, N., Peters, A., Pischon, T., Schipf, S., Schmidt, B., Stang, A., Thierry, S., Willich, S.N., Wirkner, K., Leitzmann, M.F. and Sedlmeier, A.M.
Deutsches Arzteblatt International 121 : 207-13. 5 April 2024

Systems biology approach uncovers candidates for liver-heart interorgan crosstalk in HFpEF.
Strocchi, S., Liu, L., Wang, R., Häseli, S.P., Capone, F., Bode, D., Nambiar, N., Eroglu, T., Santiago Padilla, L., Farrelly, C., Vacca, A., Mascagni, M., Oeing, C.U., Kintscher, U., Jung, S., Diezel, S.A., Liévano Contreras, S.V., Zhou, M., Seldin, M. and Schiattarella, G.G.
Circulation Research 135 (8): 873-876. 27 September 2024

Titin's cardiac-specific N2B element is critical to mechanotransduction during volume overload of the heart.
Strom, J., Bull, M., Gohlke, J., Saripalli, C., Methawasin, M., Gotthardt, M. and Granzier, H.
Journal of Molecular and Cellular Cardiology 191 : 40-49. June 2024

EU-LIFE charter of independent life science research institutes.
Superti-Furga, G., Agostinho, M., Bury, J., Cook, S., Durinx, C., Ender, A., van Luenen, H., Lund, A.H., Medema, R.H., Miączyńska, M., Nickel, D., Pelicci, P.G., Puisieux, A., Ripatti, S., Sander, M., Schubeler, D., Serrano, L., Sommer, T., Sonne-Hansen, K., Tomančák, P., Vives, J., Vontas, J. and Bettencourt-Dias, M.
FEBS Letters 598 (7): 719-724. April 2024

Macrocephaly and digital anomalies expand the phenotypic spectrum of PGAP2 variants in hyperphosphatasia with impaired intellectual development syndrome 3 (HPMRS3).
Susgun, S., Ben-Mahmoud, A., Rüschendorf, F., Ku, B., Hussain, S.I., Schulz, S., Puk, O., Biskup, S., Labonne, J.D.J., Don, D.W., Gupta, V., Choi, T.I., Khan, S., Wasif, N., Lacassie, Y., Layman, L.C., Ugur Iseri, S.A., Kim, C.H. and Kim, H.G.
Human Mutation 2024 : 1-13. 5 January 2024

Interleukin 11 therapy causes acute left ventricular dysfunction.
Sweeney, M., O’Fee, K., Villanueva-Hayes, C., Rahman, E., Lee, M., Tam, C.N., Pascual-Navarro, E., Maatz, H., Lindberg, E.L., Vanezis, K., Ramachandra, C.J., Andrew, Iv., Jennings, E.R., Lim, W.W., Widjaja, A.A., Carling, D., Hausenloy, D.J., Hubner, N., Barton, P.J.R. and Cook, S.A.
Cardiovascular Research : cvae224. 9 October 2024 (In Press)

Plasma NGAL levels in stable kidney transplant recipients and the risk of allograft loss.
Swolinsky, J.S., Hinz, R.M., Markus, C.E., Singer, E., Bachmann, F., Halleck, F., Kron, S., Naik, M.G., Schmidt, D., Obermeier, M., Gebert, P., Rauch, G., Kropf, S., Haase, M., Budde, K., Eckardt, K.U., Westhoff, T.H. and Schmidt-Ott, K.M.
Nephrology Dialysis Transplantation 39 (3): 483-495. March 2024

A single dose of cocaine rewires the 3D genome structure of midbrain dopamine neurons.
Szabó, D., Franke, V., Bianco, S., Batiuk, M.Y., Paul, E.J., Kukalev, A., Pfisterer, U.G., Irastorza-Azcarate, I., Chiariello, A.M., Demharter, S., Zea-Redondo, L., Lopez-Atalaya, J.P., Nicodemi, M., Akalin, A., Khodosevich, K., Ungless, M.A., Winick-Ng, W. and Pombo, A.
bioRxiv : 2024.05.10.593308. 12 May 2024

The STRING database in 2025: protein networks with directionality of regulation.
Szklarczyk, D., Nastou, K., Koutrouli, M., Kirsch, R., Mehryary, F., Hachilif, R., Hu, D., Peluso, M.E., Huang, Q., Fang, T., Doncheva, N.T., Pyysalo, S., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 18 November 2024 (In Press)

Protein biomarkers of adverse clinical features and events in sarcomeric hypertrophic cardiomyopathy.
Tahir, U.A., Kolm, P., Kwong, R.Y., Desai, M.Y., Dolman, S.F., Deng, S., Appelbaum, E., Desvigne-Nickens, P., DiMarco, J.P., Tiwari, G., Friedrich, M.G., Zelaya-Portillo, J.H., Jerosch-Herold, M., Kim, D.Y., Maron, M.S., Piechnik, S.K., Schulz-Menger, J., Watkins, H., Weintraub, W.S., Neubauer, S., Kramer, C.M., Jarolim, P., Gerszten, R.E. and Ho, C.Y.
Circulation Heart Failure 17 (12): e011707. December 2024

In vivo monitoring of renal tubule volume fraction using dynamic parametric MRI.
Tasbihi, E., Gladytz, T., Millward, J.M., Periquito, J.S., Starke, L., Waiczies, S., Cantow, K., Seeliger, E. and Niendorf, T.
Magnetic Resonance in Medicine 91 (6): 2532-2545. June 2024

Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.
Teixeira Alves, L.G., Baumgardt, M., Langner, C., Fischer, M., Maria Adler, J., Bushe, J., Firsching, T.C., Mastrobuoni, G., Grobe, J., Hoenzke, K., Kempa, S., Gruber, A.D., Hocke, A.C., Trimpert, J., Wyler, E. and Landthaler, M.
BMJ Open Respiratory Research 11 (1) 29 February 2024

Precision fMRI and cluster-failure in the individual brain.
Tellez Ceja, I.F., Gladytz, T., Starke, L., Tabelow, K., Niendorf, T. and Reimann, H.M.
Human Brain Mapping 45 (12): e26813. 15 August 2024

RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth.
Tetik-Elsherbiny, N., Elsherbiny, A., Setya, A., Gahn, J., Tang, Y., Gupta, P., Dou, Y., Serke, H., Wieland, T., Dubrac, A., Heineke, J., Potente, M., Cordero, J., Ola, R. and Dobreva, G.
Nature Cardiovascular Research 3 (10): 1199-1216. October 2024

Review: Opportunities and barriers for omics-based biomarker discovery in steatotic liver diseases.
Thiele, M., Villesen, I.., Niu, L., Johansen, S., Sulek, K., Nishijima, S., Van Espen, L., Keller, M., Israelsen, M., Suvitaival, T., de Zawadzki, A., Juel, H.B., Brol, M.J., Stinson, S.E., Huang, Y., Alvarez Silva, M.C., Kuhn, M., Anastasiadou, E., Leeming, D.J., Karsdal, M., Matthijnssens, J., Arumugam, M., Dalgaard, L.T., Legido-Quigley, C., Mann, M., Trebicka, J., Bork, P., Jensen, L.J., Hansen, T. and Krag, A.
Journal of Hepatology 81 (2): 345-359. August 2024

A systematic review of observational studies on the association between diet quality patterns and visceral adipose tissue.
Thimm, A., Maskarinec, G., Guillermo, C., Nimptsch, K. and Pischon, T.
British Journal of Nutrition 12 November 2024 (In Press)

The influence of post-processing software on quantitative results in 4D flow cardiovascular magnetic resonance examinations.
Trauzeddel, R.F., Müller, M., Demir, A., Wiesemann, S., Daud, E., Schmitter, S., Viezzer, D., Hadler, T. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 11 : 1465554. 27 September 2024

Histone H3.3 lysine 9 and 27 control repressive chromatin at cryptic enhancers and bivalent promoters.
Trovato, M., Bunina, D., Yildiz, U., Fernandez-Novel Marx, N., Uckelmann, M., Levina, V., Perez, Y., Janeva, A., Garcia, B.A., Davidovich, C., Zaugg, J.B. and Noh, K.M.
Nature Communications 15 (1): 7557. 30 August 2024

KCNQ5 controls perivascular adipose tissue–mediated vasodilation.
Tsvetkov, D., Schleifenbaum, J., Wang, Y., Kassmann, M., Polovitskaya, M.M., Ali, M., Schütze, S., Rothe, M., Luft, F.C., Jentsch, T.J. and Gollasch, M.
Hypertension 81 (3): 561-571. March 2024

Lifestyle interventions in cardiometabolic HFpEF: dietary and exercise modalities.
Vacca, A., Wang, R., Nambiar, N., Capone, F., Farrelly, C., Mostafa, A., Sechi, L.A. and Schiattarella, G.G.
Heart Failure Reviews 16 September 2024 (In Press)

From gut to heart: role of indole-3-propionic acid in HFpEF.
Vacca, A. and Schiattarella, G.G.
Circulation Research 134 (4): 390-392. 16 February 2024

Loss of cardiac splicing regulator RBM20 is associated with early-onset atrial fibrillation.
Vad, O.B., Angeli, E., Liss, M., Ahlberg, G., Andreasen, L., Christophersen, I.E., Hansen, C.C., Møller, S., Hellsten, Y., Haunsoe, S., Tveit, A., Svendsen, J.H., Gotthardt, M., Lundegaard, P.R. and Olesen, M.S.
JACC: Basic to Translational Science 9 (2): 163-180. February 2024

Bifidobacterium and lactobacillus probiotics and gut dysbiosis in preterm infants: the PRIMAL randomized clinical trial.
Van Rossum, T., Haiß, A., Knoll, R.L., Marißen, J., Podlesny, D., Pagel, J., Bleskina, M., Vens, M., Fortmann, I., Siller, B., Ricklefs, I., Klopp, J., Hilbert, K., Meyer, C., Thielemann, R., Goedicke-Fritz, S., Kuntz, M., Wieg, C., Teig, N., Körner, T., Kribs, A., Hudalla, H., Knuf, M., Stein, A., Gille, C., Bagci, S., Dohle, F., Proquitté, H., Olbertz, D.M., Schmidt, E., Koch, L., Pirr, S., Rupp, J., Spiegler, J., Kopp, M.V., Göpel, W., Herting, E., Forslund, S.K., Viemann, D., Zemlin, M., Bork, P., Gehring, S., König, I.R., Henneke, P. and Härtel, C.
JAMA Pediatrics 178 (10): 985-995. October 2024

Reslice3Dto2D: Introduction of a software tool to reformat 3D volumes into reference 2D slices in cardiovascular magnetic resonance imaging.
Viezzer, D., Fenski, M., Grandy, T.H., Kuhnt, J., Hadler, T., Lange, S. and Schulz-Menger, J.
BMC Research Notes 17 (1): 270. 17 September 2024

Post-hoc standardisation of parametric T1 maps in cardiovascular magnetic resonance imaging: a proof-of-concept.
Viezzer, D., Hadler, T., Gröschel, J., Ammann, C., Blaszczyk, E., Kolbitsch, C., Hufnagel, S., Kranzusch-Groß, R., Lange, S. and Schulz-Menger, J.
EBioMedicine 102 : 105055. April 2024

The IsletTester mouse: an immunodeficient model with stable hyperglycemia for the study of human islets.
Waite, E.L., Tigue, M., Yu, M., Lahori, D., Kelly, K., May, C.L., Naji, A., Roman, J., Doliba, N., Avrahami, D., Nguyen-Ngoc, K.V., Sander, M., Glaser, B. and Kaestner, K.H.
Diabetes : db230887. 21 November 2024 (In Press)

Generation and downstream analysis of single-cell and single-nuclei transcriptomes in brain organoids.
Wandres, M., Aigner, D., Kastelic, N., Boltengagen, A., Rybak-Wolf, A. and Rajewsky, N.
Journal of Visualized Experiments (205): e66225. 29 March 2024

Socio-affective communication in Tph2-deficient rat pups: communal nesting aggravates growth retardation despite ameliorating maternal affiliation deficits.
Wang, T., Homberg, J.R., Boreggio, L., Samina, M.C.F., Castro, R.C.R., Kolk, S.M., Alenina, N., Bader, M., Dai, J. and Wöhr, M.
Molecular Autism 15 (1): 50. 29 November 2024

Cross-platform clinical proteomics using the Charité Open Standard for Plasma Proteomics (OSPP).
Wang, Z., Farztdinov, V., Sinn, L.R., Tober-Lau, P., Ludwig, D., Freiwald, A., Amari, F., Textoris-Taube, K., Niewienda, A., Welter, A.S., Wei, A.A.J., Luckau, L., Kurth, F., Selbach, M., Hartl, J., Mülleder, M. and Ralser, M.
medRxiv : 2024.05.10.24307167. 10 May 2024

Tackling metabolic defects in HFpEF.
Wang, R. and Schiattarella, G.G.
European Heart Journal 45 (17): 1494-1496. 1 May 2024

Incidence of Parkinson’s disease in Germany based on prevalence data from 70 million patients of the statutory health insurance.
Wattenbach, C., Ellrichmann, G., Feinkohl, I., Voß, S. and Brinks, R.
BMC Neurology 24 (1): 221. 27 June 2024

The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells.
Weaver, M.R., Shkoruta, D., Pellegatta, M.R., Berti, C., Palmisano, M., Ferguson, S., Hurley, E., French, J., Patel, S., Belin, S., Selbach, M., Paul, F.E., Sim, F., Poitelon, Y. and Feltri, M.L.
bioRxiv : 2024.10.30.620661v1. 31 October 2024

Large‑scale assessment of physical activity in a population using high‑resolution hip‑worn accelerometry: the German National Cohort (NAKO).
Weber, A., van Hees, V.T., Stein, M.J., Gastell, S., Steindorf, K., Herbolsheimer, F., Ostrzinski, S., Pischon, T., Brandes, M., Krist, L., Marschollek, M., Greiser, K.H., Nimptsch, K., Brandes, B., Jochem, C., Sedlmeier, A.M., Berger, K., Brenner, H., Buck, C., Castell, S., Dörr, M., Emmel, C., Fischer, B., Flexeder, C., Harth, V., Hebestreit, A., Heise, J.K., Holleczek, B., Keil, T., Koch-Gallenkamp, L., Lieb, W., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Kluttig, A., Obi, N., Peters, A., Schmidt, B., Schipf, S., Schulze, M.B., Teismann, H., Waniek, S., Willich, S.N., Leitzmann, M.F. and Baurecht, H.
Scientific Reports 14 (1): 7927. 4 April 2024

Combining Data Independent Acquisition with spike-in SILAC (DIA-SiS) improves proteome coverage and quantification.
Welter, A.S., Gerwien, M., Kerridge, R., Alp, K.M., Mertins, P. and Selbach, M.
Molecular & Cellular Proteomics 23 (10): 100839. October 2024

TPT-004, a next-generation inhibitor of tryptophan hydroxylase, ameliorates pulmonary arterial hypertension in rats.
Wesolowski, R., Pleimes, D., Specker, E. and Bader, M.
Journal of the American Heart Association 13 (10): e034240. 21 May 2024

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
Widjaja, A.A., Lim, W.W., Viswanathan, S., Chothani, S., Corden, B., Dasan, C.M., Goh, J.W.T., Lim, R., Singh, B.K., Tan, J., Pua, C.J., Lim, S.Y., Adami, E., Schafer, S., George, B.L., Sweeney, M., Xie, C., Tripathi, M., Sims, N.A., Hübner, N., Petretto, E., Withers, D.J., Ho, L., Gil, J., Carling, D. and Cook, S.A.
Nature 632 (8023): 157-165. 1 August 2024

Health service use among migrants in the German National Cohort - the role of birth region and language skills.
Wiessner, C., Licaj, S., Klein, J., Bohn, B., Brand, T., Castell, S., Führer, A., Harth, V., Heier, M., Heise, J.K., Holleczek, B., Jaskulski, S., Jochem, C., Koch-Gallenkamp, L., Krist, L., Leitzmann, M., Lieb, W., Meinke-Franze, C., Mikolajczyk, R., Moreno Velásquez, I., Obi, N., Pischon, T., Schipf, S., Thierry, S., Willich, S.N., Zeeb, H. and Becher, H.
International Journal of Public Health 69 : 1606377. 6 March 2024

Epigenetic regulatory layers in the 3D nucleus.
Willemin, A., Szabo, D. and Pombo, A.
Molecular Cell 84 (3): 415-428. 1 February 2024

Metformin modulates microbiota and improves blood pressure and cardiac remodeling in a rat model of hypertension.
Wimmer, M.I., Bartolomaeus, H., Anandakumar, H., Chen, C.Y., Vecera, V., Kedziora, S., Kamboj, S., Schumacher, F., Pals, S., Rauch, A., Meisel, J., Potapenko, O., Yarritu, A., Bartolomaeus, T.U.P., Samaan, M., Thiele, A., Stürzbecher, L., Geisberger, S.Y., Kleuser, B., Oefner, P.J., Haase, N., Löber, U., Gronwald, W., Forslund-Startceva, S.K., Muller, D.N. and Wilck, N.
Acta Physiologica 240 (11): e14226. November 2024

A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studies.
Wirbel, J., Essex, M., Forslund, S.K. and Zeller, G.
Genome Biology 25 (1): 247. 25 September 2024

Trophoblast side-population markers are dysregulated in preeclampsia and fetal growth restriction.
Wong, G.P., Hartmann, S., Simmons, D.G., Ellis, S., Nonn, O., Cannon, P., Nguyen, T.V., Nguyen, A., Bartho, L.A., Tong, S., Hannan, N.J. and Kaitu'u-Lino, T.J.
Stem Cell Reviews and Reports 20 (7): 1954-1970. October 2024

Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2.
Wortham, M., Ramms, B., Zeng, C., Benthuysen, J.R., Sai, S., Pollow, D.P., Liu, F., Schlichting, M., Harrington, A.R., Liu, B., Prakash, T.P., Pirie, E.C., Zhu, H., Baghdasarian, S., Auwerx, J., Shirihai, O.S. and Sander, M.
bioRxiv : 2024.02.24.581864. 28 February 2024

Fetal growth restriction induced by maternal gal-3 deficiency is associated with altered gut-placenta axis.
Xie, Y., Zhao, F., Wang, Y., Borowski, S., Freitag, N., Tirado-Gonzalez, I., Hofsink, N., Matschl, U., Plösch, T., Garcia, M.G. and Blois, S.M.
Cell Death & Disease 15 (8): 575. 8 August 2024

Transient high salt intake promotes T-cell-mediated hypertensive vascular injury.
Yakoub, M., Rahman, M., Kleimann, P., Hoffe, J., Feige, M., Bouvain, P., Alter, C., Kluczny, J.I., Reidel, S., Nederlof, R., Hering, L., Argov, D., Arifaj, D., Kantauskaite, M., Meister, J., Kleinewietfeld, M., Rump, L.C., Jantsch, J., Flögel, U., Müller, D.N., Temme, S. and Stegbauer, J.
Hypertension 81 (12): 2415-2429. December 2024

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Yalcin, F., Haneke, H., Efe, I.E., Kuhrt, L.D., Motta, E., Nickl, B., Flüh, C., Synowitz, M., Dzaye, O., Bader, M. and Kettenmann, H.
Acta Neuropathologica Communications 12 (1): 50. 2 April 2024

Grainyhead-like 2 deficiency and kidney cyst growth in a mouse model.
Yurtdas, Z.Y., Kilic, E., Boor, P., Wyler, E., Landthaler, M., Jung, K. and Schmidt-Ott, K.M.
Journal of the American Society of Nephrology 35 (7): 838-853. July 2024

The significant impact of experimental variables on the gut microbiome.
Zakarauskas-Seth, B.I. and Sawamiphak, S.
Cardiovascular Research 120 (10): 1100-1101. July 2024

The Calmodulin-interacting peptide Pcp4a regulates feeding state-dependent behavioral choice in zebrafish.
Zaupa, M., Nagaraj, N., Sylenko, A., Baier, H., Sawamiphak, S. and Filosa, A.
Neuron 112 (7): 1150-1164.e6. 3 April 2024

Lysozyme 1 inflamed CCR2(+) macrophages promote obesity-induced cardiac dysfunction.
Zhang, L., Han, H., Xu, A., Sathe, A., Fu, S., Zhao, J., Cai, W., Yang, Y., Liu, J., Bai, H., Ben, J., Zhu, X., Li, X., Yang, Q., Wang, Z., Gu, Y., Xing, C., Schiattarella, G.G., Cheng, S.Y., Zhang, H. and Chen, Q.
Circulation Research 135 (5): 596-613. 16 August 2024

Noninvasive assessment of diabetic kidney disease with MRI: hype or hope?
Zhao, K., Seeliger, E., Niendorf, T. and Liu, Z.
Journal of Magnetic Resonance Imaging 59 (5): 1494-1513. May 2024

Atypical KCNQ1/Kv7 channel function in a neonatal diabetes patient: hypersecretion preceded the failure of pancreatic β-cells.
Zhou, Z., Gong, M., Pande, A., Margineanu, A., Lisewski, U., Purfürst, B., Zhu, H., Liang, L., Jia, S., Froehler, S., Zeng, C., Kühnen, P., Khodaverdi, S., Krill, W., Röpke, T., Chen, W., Raile, K., Sander, M. and Izsvák, Z.
iScience 27 (7): 110291. 19 July 2024

Die Herausforderung der Lupusnephritis: aktuelle Erkenntnisse und Behandlungsansätze.
Zimmermann, J. and Schreiber, A.
Nephrologie aktuell 28 (6): 248-256. July 2024

Avacopan in anti-neutrophil cytoplasmic autoantibodies–associated vasculitis in a real-world setting.
Zimmermann, J., Sonnemann, J., Jabs, W.J., Schönermarck, U., Vielhauer, V., Bieringer, M., Schneider, U., Kettritz, R. and Schreiber, A.
Kidney International Reports 9 (9): 2803-2808. September 2024

Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells.
van Bentum, M., Klinger, B., Sieber, A., Lehmann, N., Haji, M., Naghiloo, S., Niquet, S., Mertins, P., Blüthgen, N. and Selbach, M.
bioRxiv : 2024.05.13.593849. 15 May 2024

Neuromuscular dysfunction in patient-derived FUS(R244RR)-ALS iPSC model via axonal downregulation of neuromuscular junction proteins.
von Kuegelgen, N., Ludwik, K., Mendonsa, S., Roemer, C., Becher, E., Breimann, L., Strauch, M., Mari, T., Mongellaz, S., Zuckerman, B., Grexa, N., Oliveras-Martinez, A., Woehler, A., Selbach, M., La Bella, V., Ulitsky, I. and Chekulaeva, M.
bioRxiv : 2024.08.17.607965. 17 August 2024

The (un)answered question: a data science powered music experiment.
von Kurnatowski, L., Wolff, B., Kernchen, S., Klapproth-Rieger, A., Heidrich, D., Haupt, C., Schreiber, A., Niendorf, T., Kosmider, A., Lobbes, M. and Hennecke, M.
Lecture Notes in Computer Science 14717 : 233-246. 2 June 2024

Transgenic rat with ubiquitous expression of angiotensin-(1-7)-producing fusion protein: a new tool to study the role of protective arm of the renin-angiotensin system in the pathophysiology of cardio-renal diseases.
Červenka, L., Husková, Z., Kikerlová, S., Gawrys, O., Vacková, Š., Škaroupková, P., Sadowski, J., Miklovič, M., Molnár, M., Táborský, M., Melenovský, V. and Bader, M.
Hypertension Research 13 November 2024 (In Press)

2023

Transgenic animal models for the functional analysis of ACE2.
Alenina, N. and Bader, M.
In: Angiotensin : from the kidney to coronavirus. Molecular Mediators in Health and Disease: How Cells Communicate . Elsevier / Academic Press, London, 491-503. ISBN 978-0-323-99618-1 2023

Sites of transcription initiation drive mRNA isoform selection.
Alfonso-Gonzalez, C., Legnini, I., Holec, S., Arrigoni, L., Ozbulut, H.C., Mateos, F., Koppstein, D., Rybak-Wolf, A., Bönisch, U., Rajewsky, N. and Hilgers, V.
Cell 186 (11): 2438-2455. 25 May 2023

Rapid nuclear deadenylation of mammalian messenger RNA.
Alles, J., Legnini, I., Pacelli, M. and Rajewsky, N.
iScience 26 (1): 105878. 20 January 2023

Constitutive depletion of brain serotonin differentially affects rats’ social and cognitive abilities.
Alonso, L., Peeva, P., Stasko, S., Bader, M., Alenina, N., Winter, Y. and Rivalan, M.
iScience 26 (2): 105998. 17 February 2023

Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain.
Alves-Silva, T., Húngaro, T.G.R., Freitas-Lima, L.C., de Melo Arthur, G., Arruda, A.C., Santos, R.B., Oyama, L.M., Mori, M.A.S., Bader, M. and Araujo, R.C.
iScience 26 (12): 108409. 15 December 2023

On multistability and constitutive relations of cell motion on Fibronectin lanes.
Amiri, B., Heyn, J.C.J., Schreiber, C., Rädler, J.O. and Falcke, M.
Biophysical Journal 122 (5): 753-766. 7 March 2023

Multilevel comparison of deep learning models for function quantification in cardiovascular magnetic resonance: on the redundancy of architectural variations.
Ammann, C., Hadler, T., Gröschel, J., Kolbitsch, C. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 10 : 1118499. 18 April 2023

Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide.
Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S.K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J.E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M.T., Hoyles, L., Alves, R., Helft, G., Isnard, R., Køber, L., Coelho, L.P., Rouault, C., Gauguier, D., Gøtze, J.P., Prifti, E., Froguel, P., Zucker, J.D., Bäckhed, F., Vestergaard, H., Hansen, T., Oppert, J.M., Blüher, M., Nielsen, J., Raes, J., Bork, P., Yaqoob, M.M., Stumvoll, M., Pedersen, O., Ehrlich, S.D., Clément, K. and Dumas, M.E.
Nature Communications 14 (1): 5843. 20 September 2023

Interferon-γ drives macrophage reprogramming, cerebrovascular remodeling, and cognitive dysfunction in a zebrafish and a mouse model of ion imbalance and pressure overload.
Apaydin, D.C., Zakarauskas-Seth, B.I., Carnevale, L., Apaydin, O., Perrotta, M., Carnevale, R., Kotini, M.P., Kotlar-Goldaper, I., Belting, H.G., Carnevale, D., Filosa, A. and Sawamiphak, S.
Cardiovascular research 119 (5): 1234-1249. May 2023

Alpha-1 adrenergic signaling drives cardiac regeneration via extracellular matrix remodeling transcriptional program in zebrafish macrophages.
Apaydin, O., Altaikyzy, A., Filosa, A. and Sawamiphak, S.
Developmental Cell 58 (22): 2460-2476.e7. 20 November 2023

Stress perfusion cardiac magnetic resonance vs SPECT imaging for detection of coronary artery disease.
Arai, A.E., Schulz-Menger, J., Shah, D.J., Han, Y., Bandettini, W.P., Abraham, A., Woodard, P.K., Selvanayagam, J.B., Hamilton-Craig, C., Tan, R.S., Carr, J., Teo, L., Kramer, C.M., Wintersperger, B.J., Harisinghani, M.G., Flamm, S.D., Friedrich, M.G., Klem, I., Raman, S.V., Haverstock, D., Liu, Z., Brueggenwerth, G., Santiuste, M., Berman, D.S. and Pennell, D.J.
Journal of the American College of Cardiology 82 (19): 1828-1838. 7 November 2023

Linee guida ESC 2023 per il trattamento delle cardiomiopatie [2023 ESC Guidelines for the management of cardiomyopathies].
Arbelo, E., Protonotarios, A., Gimeno, J.R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C.R., Biagini, E., Blom, N.A., de Boer, R.A., De Winter, T., Elliott, P.M., Flather, M., Garcia-Pavia, P., Haugaa, K.H., Ingles, J., Jurcut, R.O., Klaassen, S., Limongelli, G., Loeys, B., Mogensen, J., Olivotto, I., Pantazis, A., Sharma, S., Van Tintelen, J.P., Ware, J.S. and Kaski, J.P.
Giornale Italiano di Cardiologia 24 (11): 1e-127e. November 2023

2023 ESC Guidelines for the management of cardiomyopathies: developed by the task force on the management of cardiomyopathies of the European Society of Cardiology (ESC).
Arbelo, E., Protonotarios, A., Gimeno, J.R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C.R., Biagini, E., Blom, N.A., de Boer, R.A., De Winter, T., Elliott, P.M., Flather, M., Garcia-Pavia, P., Haugaa, K.H., Ingles, J., Jurcut, R.O., Klaassen, S., Limongelli, G., Loeys, B., Mogensen, J., Olivotto, I., Pantazis, A., Sharma, S., Van Tintelen, J.P., Ware, J.S. and Kaski, J.P.
European Heart Journal 44 (37): 3503-3626. 1 October 2023

Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G., Bartolomaeus, H., Rauch, A., Chen, C.Y., N'Diaye, G., Löber, U., Bartolomaeus, T.U.P., Fritsche-Guenther, R., Rodrigues, A.F., Yarritu, A., Zhong, C., Fei, L., Tsvetkov, D., Todiras, M., Park, J.K., Markó, L., Maifeld, A., Patzak, A., Bader, M., Kempa, S., Kirwan, J.A., Forslund, S.K., Müller, D.N. and Wilck, N.
Cardiovascular Research 119 (6): 1441-1452. May 2023

GPER activation attenuates cardiac dysfunction by upregulating the SIRT1/3-AMPK-UCP2 pathway in postmenopausal diabetic rats.
Azizian, H., Farhadi, Z., Bader, M., Ghalenoei, J.A., Ghafari, M.A. and Mahmoodzadeh, S.
PLoS ONE 18 (12): e0293630. 22 December 2023

Renal MRI: from nephron to NMR signal.
Bane, O., Seeliger, E., Cox, E., Stabinska, J., Bechler, E., Lewis, S., Hickson, L.T.J., Francis, S., Sigmund, E. and Niendorf, T.
Journal of Magnetic Resonance Imaging 58 (6): 1660-1679. December 2023

Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C.
Beagrie, R.A., Thieme, C.J., Annunziatella, C., Baugher, C., Zhang, Y., Schueler, M., Kukalev, A., Kempfer, R., Chiariello, A.M., Bianco, S., Li, Y., Davis, T., Scialdone, A., Welch, L.R., Nicodemi, M. and Pombo, A.
Nature Methods 20 (7): 1037-1047. July 2023

Impact of genetic deletion of MrgD or Mas receptors in depressive-like behaviour in mice.
Becari, L., Fonseca, M.L.A., Gonçalves, S.C.A, Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Acta Neuropsychiatrica 35 (1): 27-34. February 2023

Current practice of blood pressure measurement in Germany: a nationwide questionnaire-based survey in medical practices.
Beger, C., Mayerböck, A., Klein, K., Karg, T., Schmidt-Ott, K.M., Randerath, O. and Limbourg, F.P.
Blood Pressure 32 (1): 2165901. 2023

Towards monitoring of antimicrobial resistance in the environment: For what reasons, how to implement it, and what are the data needs?
Bengtsson-Palme, J., Abramova, A., Berendonk, T.U., Coelho, L.P., Forslund, S.K., Gschwind, R., Heikinheimo, A., Jarquín-Díaz, V.H., Khan, A.A., Klümper, U., Löber, U., Nekoro, M., Osińska, A.D., Ugarcina Perovic, S., Pitkänen, T., Rødland, E.K., Ruppé, E., Wasteson, Y., Wester, A.L. and Zahra, R.
Environment International 178 : 108089. 5 July 2023

MRI of implantation sites using parallel transmission of an optimized radiofrequency excitation vector.
Berangi, M., Kuehne, A., Waiczies, H. and Niendorf, T.
Tomography 9 (2): 603-620. 8 March 2023

Myocardial injury in patients with acute ischemic stroke detected by cardiovascular magnetic resonance imaging.
Blaszczyk, E., Hellwig, S., Saad, H., Ganeshan, R., Stengl, H., Nolte, C.H., Fiebach, J.B., Endres, M., Kuhnt, J., Gröschel, J., Schulz-Menger, J. and Scheitz, J.F.
European Journal of Radiology 165 : 110908. 7 June 2023

Combining metabolic pulse labeling and quantitative proteomics to monitor protein synthesis upon viral infection.
Bogdanow, B., Katsimani, N., Liu, F. and Selbach, M.
Methods in Molecular Biology 2610 : 149-165. 2023

90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection.
Bosquillon de Jarcy, L., Akbil, B., Mhlekude, B., Leyens, J., Postmus, D., Harnisch, G., Jansen, J., Schmidt, M.L., Aigner, A., Pott, F., Chua, R.L., Krist, L., Gentile, R., Mühlemann, B., Jones, T.C., Niemeyer, D., Fricke, J., Keil, T., Pischon, T., Janke, J., Conrad, C., Iacobelli, S., Drosten, C., Corman, V.M., Ralser, M., Eils, R., Kurth, F., Sander, L. and Goffinet, C.
Clinical and Experimental Medicine 23 (7): 3689-3700. November 2023

Cardiovascular peptide hormones - special edition.
Braga, T.V., Mervaala, E., Santos, R. and Bader, M.
Peptides 167 : 171062. September 2023

Evolution and implications of de novo genes in humans.
Broeils, L.A., Ruiz-Orera, J., Snel, B., Hubner, N. and van Heesch, S.
Nature Ecology & Evolution 7 (6): 804-815. June 2023

Fluid shear stress induces a shift from glycolytic to amino acid pathway in human trophoblasts.
Brugger, B.A., Neuper, L., Guettler, J., Forstner, D., Wernitznig, S., Kummer, D., Lyssy, F., Feichtinger, J., Krappinger, J., El-Heliebi, A., Bonstingl, L., Moser, G., Rodriguez-Blanco, G., Bachkönig, O.A., Gottschalk, B., Gruber, M., Nonn, O., Herse, F., Verlohren, S., Frank, H.G., Barapatre, N., Kampfer, C., Fluhr, H., Desoye, G. and Gauster, M.
Cell and Bioscience 13 (1): 163. 8 September 2023

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Budu-Aggrey, A., Kilanowski, A., Sobczyk, M.K., Shringarpure, S.S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B.M., Thomas, L.F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J.V.T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A., Jeong, A., Fawcett, K.A., Baurecht, H., Rodriguez, E., Alves, A.C., Kumar, A., Sleiman, P.M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C.J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C.A., Thiering, E., Wu, B., Kress, S., Kothalawala, D.M., Kadalayil, L., Duan, J., Zhang, H., Hadebe, S., Hoffmann, T., Jorgenson, E., Choquet, H., Risch, N., Njølstad, P., Andreassen, O.A., Johansson, S., Almqvist, C., Gong, T., Ullemar, V., Karlsson, R., Magnusson, P.K.E., Szwajda, A., Burchard, E.G., Thyssen, J.P., Hansen, T., Kårhus, L.L., Dantoft, T.M., Jeanrenaud, A.C.S.N., Ghauri, A., Arnold, A., Homuth, G., Lau, S., Nöthen, M.M., Hübner, N., Imboden, M., Visconti, A., Falchi, M., Bataille, V., Hysi, P., Ballardini, N., Boomsma, D.I., Hottenga, J.J., Müller-Nurasyid, M., Ahluwalia, T.S., Stokholm, J., Chawes, B., Schoos, A.M.M., Esplugues, A., Bustamante, M., Raby, B., Arshad, S., German, C., Esko, T., Milani, L.A., Metspalu, A., Terao, C., Abuabara, K., Løset, M., Hveem, K., Jacobsson, B., Pino-Yanes, M., Strachan, D.P., Grarup, N., Linneberg, A., Lee, Y., Probst-Hensch, N., Weidinger, S., Jarvelin, M.R., Melén, E., Hakonarson, H., Irvine, A.D., Jarvis, D., Nijsten, T., Duijts, L., Vonk, J.M., Koppelmann, G.H., Godfrey, K.M., Barton, S.J., Feenstra, B., Pennell, C.E., Sly, P.D., Holt, P.G., Williams, L.K., Bisgaard, H., Bønnelykke, K., Curtin, J., Simpson, A., Murray, C., Schikowski, T., Bunyavanich, S., Weiss, S.T., Holloway, J.W., Min, J.L., Brown, S.J., Standl, M. and Paternoster, L.
Nature Communications 14 (1): 6172. 4 October 2023

LRP2 contributes to planar cell polarity-dependent coordination of motile cilia function.
Bunatyan, L., Margineanu, A., Boutin, C., Montcouquiol, M., Bachmann, S., Christensen, E.I., Willnow, T.E. and Christ, A.
Cell and Tissue Research 392 (2): 535-551. May 2023

Nonsense mediated decay factor UPF3B is associated with cMyBP-C haploinsufficiency in hypertrophic cardiomyopathy patients.
Burkart, V., Kowalski, K., Disch, A., Hilfiker-Kleiner, D., Lal, S., Dos Remedios, C., Perrot, A., Zeug, A., Ponimaskin, E., Kosanke, M., Dittrich-Breiholz, O., Kraft, T. and Montag, J.
Journal of Molecular and Cellular Cardiology 185 : 26-37. December 2023

Autoantibodies targeting G protein-coupled receptors: an evolving history in autoimmunity. Report of the 4th international symposium.
Cabral-Marques, O., Moll, G., Catar, R., Preuß, B., Bankamp, L., Pecher, A.C., Henes, J., Klein, R., Kamalanathan, A.S., Akbarzadeh, R., van Oostveen, W., Hohberger, B., Endres, M., Koolmoes, B., Levarht, N., Postma, R., van Duinen, V., van Zonneveld, A.J., de Vries-Bouwstra, J., Fehres, C., Tran, F., do Vale, F.Y.N., da Silva Souza, K.B., Filgueiras, I.S., Schimke, L.F., Baiocchi, G.C., de Miranda, G.C., da Fonseca, D.L.M., Freire, P.P., Hackel, A.M., Grasshoff, H., Stähle, A., Müller, A., Dechend, R., Yu, X., Petersen, F., Sotzny, F., Sakmar, T.P., Ochs, H.D, Schulze-Forster, Kai, Heidecke, H., Scheibenbogen, C., Shoenfeld, Y. and Riemekasten, G.
Autoimmunity Reviews 22 (5): 103310. May 2023

AT1-AA infusion during pregnancy impairs CBF autoregulation postpartum.
Campbell, N., Strong, L., Fang, X., Border, J.J., Herrock, O., Turner, T., Deer, E., Amaral, L., Dechend, R., Roman, R.J. and LaMarca, B.
International Journal of Cerebrovascular Disease and Stroke 6 (1): 154. 17 July 2023

Monitoring kidney size to interpret MRI-based assessment of renal oxygenation in acute pathophysiological scenarios.
Cantow, K., Gladytz, T., Millward, J.M., Waiczies, S., Niendorf, T. and Seeliger, E.
Acta Physiologica 237 (2): e13868. February 2023

Cardiometabolic HFpEF: NASH of the heart.
Capone, F., Vettor, Roberto and Schiattarella, G.G.
Circulation 147 (6): 451-453. 7 February 2023

Impact of high salt-intake on a natural gut ecosystem in wildling mice.
Cardilli, A., Hamad, I., Dyczko, A., Thijs, S., Vangronsveld, J., Müller, D.N., Rosshart, S.P. and Kleinewietfeld, M.
Nutrients 15 (7): 1565. 23 March 2023

Cerebrovascular G(i) proteins protect against brain hypoperfusion and collateral failure in cerebral ischemia.
Castaneda-Vega, S., Beer-Hammer, S., Leiss, V., Napieczyńska, H., Vuozzo, M., Schmid, A.M., Zeng, H., He, Y., Kohlhofer, U., Gonzalez-Menendez, I., Quintanilla-Martinez, L., Hempel, J.M., Gollasch, M., Yu, X., Pichler, B.J. and Nürnberg, B.
Molecular Imaging and Biology 25 (2): 363-374. April 2023

Brown adipose tissue transcriptome unveils an important role of the Beta-alanine/alamandine receptor, MrgD, in metabolism.
Cerri, G.C., Santos, S.H.S., Bader, M. and Dos Santos, R.A.S.
Journal of nutritional biochemistry 114 : 109268. April 2023

Dipeptidyl peptidase 1 inhibition as a potential therapeutic approach in neutrophil-mediated inflammatory disease.
Chalmers, J.D., Kettritz, R. and Korkmaz, B.
Frontiers in Immunology 14 : 1239151. 14 December 2023

LongDat: an R package for covariate-sensitive longitudinal analysis of high-dimensional data.
Chen, C.Y., Löber, U. and Forslund, S.K.
Bioinformatics Advances 3 (1): vbad063. 18 May 2023

A guide to naming eukaryotic circular RNAs.
Chen, L.L., Bindereif, A., Bozzoni, I., Chang, H.Y., Matera, A.G., Gorospe, M., Hansen, T.B., Kjems, J., Ma, X.K., Pek, J.W., Rajewsky, N., Salzman, J., Wilusz, J.E., Yang, L. and Zhao, F.
Nature Cell Biology 25 (1): 1-5. January 2023

Novel candidate regulators and developmental trajectory of pituitary thyrotropes.
Cheung, L.Y.M., Menage, L., Rizzoti, K., Hamilton, G., Dumontet, T., Basham, K., Daly, A.Z., Brinkmeier, M.L., Masser, B.E., Treier, M., Cobb, J., Delogu, A., Lovell-Badge, R., Hammer, G.D. and Camper, S.A.
Endocrinology 164 (6): bqad076. June 2023

Physics-based polymer models to probe chromosome structure in single molecules.
Conte, M., Chiariello, A.M., Bianco, S., Esposito, A., Abraham, A. and Nicodemi, M.
Methods in Molecular Biology 2655 : 57-66. 2023

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.
Costanzo, M.C., von Grotthuss, M., Massung, J., Jang, D., Caulkins, L., Koesterer, R., Gilbert, C., Welch, R.P., Kudtarkar, P., Hoang, Q., Boughton, A.P., Singh, P., Sun, Y., Duby, M., Moriondo, A., Nguyen, T., Smadbeck, P., Alexander, B.R., Brandes, M.K., Carmichael, M., Dornbos, P., Green, T., Huellas-Bruskiewicz, K.C., Ji, Y., Kluge, A., McMahon, A.C., Mercader, J.M., Ruebenacker, O., Sengupta, S., Spalding, D., Taliun, D., Smith, P., Thomas, M.K., Akolkar, B., Brosnan, M.J., Cherkas, A., Chu, A.Y., Fauman, E.B., Fox, C.S., Kamphaus, T.N., Miller, M.R., Nguyen, L., Parsa, A., Reilly, D.F., Ruetten, H., Wholley, D., Zaghloul, N.A., Abecasis, G.R., Altshuler, D., Keane, T.M., McCarthy, M.I., Gaulton, K.J., Florez, J.C., Boehnke, M., Burtt, N.P. and Flannick, J.
Cell Metabolism 35 (4): 695-710.e6. 4 April 2023

Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing.
Cui, L., Yang, B., Xiao, S., Gao, J., Baud, A., Graham, D., McBride, M., Dominiczak, A., Schafer, S., Aumatell, R.L., Mont, C., Teruel, A.F., Hübner, N., Flint, J., Mott, R. and Huang, L.
Genome Biology 24 (1): 215. 29 September 2023

Arterial myogenic response and aging.
Cui, Y., Gollasch, M. and Kassmann, M.
Ageing Research Reviews 84 : 101813. February 2023

Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.
Côrte-Real, B.F., Hamad, I., Arroyo Hornero, R., Geisberger, S., Roels, J., Van Zeebroeck, L., Dyczko, A., van Gisbergen, M.W., Kurniawan, H., Wagner, A., Yosef, N., Weiss, S.N.Y., Schmetterer, K.G., Schröder, A., Krampert, L., Haase, S., Bartolomaeus, H., Hellings, N., Saeys, Y., Dubois, L.J., Brenner, D., Kempa, S., Hafler, D.A., Stegbauer, J., Linker, R.A., Jantsch, J., Müller, D.N. and Kleinewietfeld, M.
Cell Metabolism 35 (2): 299-315. 7 February 2023