2025
Food allergy genetics and epigenetics: a review of genome-wide association studies.
Arnau-Soler, A., Tremblay, B.L., Sun, Y., Madore, A.M., Simard, M., Kersten, E.T.G., Ghauri, A., Marenholz, I., Eiwegger, T., Simons, E., Chan, E.S., Nadeau, K., Sampath, V., Mazer, B.D., Elliott, S., Hampson, C., Soller, L., Sandford, A., Begin, P., Hui, J., Wilken, B.F., Gerdts, J., Bourkas, A., Ellis, A.K., Vasileva, D., Clarke, A., Eslami, A., Ben-Shoshan, M., Martino, D., Daley, D., Koppelman, G.H., Laprise, C., Lee, Y.A. and Asai, Y.
Allergy 80
(1): 106-131.
January 2025
Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface.
Avery, E.G., Haag, L.M., McParland, V., Kedziora, S.M., Zigra, G.J., Valdes, D.S., Kirchner, M., Popp, O., Geisberger, S., Nonn, O., Karlsen, T.V., N'Diaye, G., Yarritu, A., Bartolomaeus, H., Bartolomaeus, T.U.P., Tagiyeva, N.A., Wimmer, M.I., Haase, N., Zhang, Y.D., Wilhelm, A., Grütz, G., Tenstad, O., Wilck, N., Forslund, S.K., Klopfleisch, R., Kühl, A.A., Atreya, R., Kempa, S., Mertins, P., Siegmund, B., Wiig, H. and Müller, D.N.
Cardiovascular Research
: cvae267.
13 January 2025
(In Press)
The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes.
Eibach, Y., Kreher, S., Poetsch, M.S., Kho, A.L., Gaertner, U., Clemen, C.S., Schröder, R., Guo, K., Milting, H., Meder, B., Potente, M., Richter, M., Schneider, A., Meiners, S., Gaute, M. and Braun, T.
Science Advances 11
(4): eado3852.
24 January 2025
Targeting Runx1 protects against heart failure with preserved ejection fraction.
Elbassioni, A.A.M., Raheem, A.A., Song, J., Johnston, A.S., Trivett, C., Lin, H., Zhang, H., Bradley, A., Higgins, E., Mooney, L., Koay, Y.C., O'Toole, D., Herzyk, P., Nixon, C., Blyth, K., O'Sullivan, J.F., Lang, N.N., Berry, C., Braun, T., Schiattarella, G.G., Giacca, M., McBride, M.W., Nicklin, S.A., Cameron, E.R., Loughrey, C.M. and MacDonald, E.A.
bioRxiv
: 2025.01.24.634831.
27 January 2025
Response to the letter to the editor: "cardiovascular magnetic resonance reveals myocardial involvement in patients with active stage of inflammatory bowel disease" (CRCD-D-24-01694).
Fenski, M. and Schulz-Menger, J.
Clinical Research in Cardiology
5 February 2025
(In Press)
Loss of structural specificity in 3D genome organization upon viral infection is predicted by polymer physics.
Fontana, A., Bianco, S., Tafuri, F., Esposito, A., Abraham, A., Conte, M., Vercellone, F., Di Pierno, F., Kundu, S., Guha, S., Di Carluccio, C., Prisco, A., Nicodemi, M. and Chiariello, A.M.
Journal of Chemical Physics 162
(1): 014903.
7 January 2025
Sex hormone-dependent host-microbiome interactions and cardiovascular risk (XCVD): design of a longitudinal multi-omics cohort study.
Franz, K., Markó, L., Mähler, A., Chakaroun, R., Heinitz, S., Schlögl, H., Sacher, J., Steckhan, N., Dechend, R., Adams, N., Andersen, M., Glintborg, D., Viehweger, M., Bahr, L.S. and Forslund-Startceva, S.K.
BMJ Open 15
(1): e087982.
9 January 2025
Stress CMR perfusion imaging in the medicare-eligible population: insights from the SPINS study.
Ge, Y., Antiochos, P., Bernhard, B., Heydari, B., Steel, K., Bingham, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Shanbhag, S.M., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 18
(1): 33-44.
January 2025
Costs associated with insufficient physical activity in Germany: cross-sectional results from the baseline examination of the German national cohort (NAKO).
Gottschalk, S., König, H.H., Weber, A., Leitzmann, M.F., Stein, M.J., Peters, A., Flexeder, C., Krist, L., Willich, S.N., Nimptsch, K., Pischon, T., Gastell, S., Steindorf, K., Herbolsheimer, F., Ebert, N., Michels, K.B., Dorrn, A., Harth, V., Obi, N., Karch, A., Teismann, H., Völzke, H., Meinke-Franze, C., Klimeck, L., Seum, T.L. and Dams, J.
European Journal of Health Economics 26
(1): 117-128.
February 2025
Detecting unforeseen data properties with diffusion autoencoder embeddings using ppine MRI data.
Graf, R., Hunecke, F., Pohl, S., Atad, M., Moeller, H., Starck, S., Kroencke, T., Bette, S., Bamberg, F., Pischon, T., Niendorf, T., Schmidt, C., Paetzold, J.C., Rueckert, D. and Kirschke, J.S.
Lecture Notes in Computer Science 2024
(15274): 79-88.
17 January 2025
Gut-derived metabolites as treatment targets in chronic kidney disease - an avenue toward personalized medicine.
Holle, J. and Bartolomaeus, H.
Pediatric Nephrology
16 January 2025
(In Press)
Unraveling the distinctive gut microbiome of khulans (Equus hemionus hemionus) in comparison to their drinking water and closely related equids.
Jarquín-Díaz, V.H., Dayaram, A., Soilemetzidou, E.S., Desvars-Larrive, A., Bohner, J., Buuveibaatar, B., Kaczensky, P., Walzer, C., Greenwood, A.D. and Löber, U.
Scientific Reports 15
(1): 2767.
22 January 2025
Centromere positioning orchestrates telomere bouquet formation and the initiation of meiotic differentiation.
Jiménez-Martín, A., Pineda-Santaella, A., Martín-García, R., Esteban-Villafañe, R., Matarrese, A., Pinto-Cruz, J., Camacho-Cabañas, S., León-Periñán, D., Terrizzano, A., Daga, R.R., Braun, S. and Fernández-Álvarez, A.
Nature Communications 16
(1): 837.
20 January 2025
Deep learning-based whole-brain B(1)(+)-mapping at 7T.
Krueger, F., Aigner, C.S., Lutz, M., Riemann, L.T., Degenhardt, K., Hadjikiriakos, K., Zimmermann, F.F., Hammernik, K., Schulz-Menger, J., Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 93
(4): 1700-1711.
April 2025
Beyond hemoglobin: critical role of 2,3-bisphosphoglycerate mutase in kidney function and injury.
Kulow, V.A., Roegner, K., Labes, R., Kasim, M., Mathia, S., Czopek, C.S., Berndt, N., Becker, P.N., Ter-Avetisyan, G., Luft, F.C., Enghard, P., Hinze, C., Klocke, J., Eckardt, K.U., Schmidt-Ott, K.M., Persson, P.B., Rosenberger, C. and Fähling, M.
Acta Physiologica 241
(1): e14242.
January 2025
Multicenter validation of secondary hemophagocytic lymphohistiocytosis diagnostic criteria.
Lachmann, G., Heeren, P., Schuster, F.S., Nyvlt, P., Spies, C., Feinkohl, I., Schenk, T., Ammouri, W., Debaugnies, F., Galicier, L., Jia, Y., Meena, N., Nagant, C., Neth, O., Nierkens, S., San Martin, J., Sun, H.W.L., Wang, Y., Wang, Z., Yoon, J.H., Brunkhorst, F.M., La Rosée, P., Janka, G. and Lachmann, C.
Journal of Internal Medicine
27 January 2025
(In Press)
Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progression.
Laschtowitz, A., Lindberg, E.L., Liebhoff, A.M., Liebig, L.A., Casar, C., Steinmann, S., Guillot, A., Xu, J., Schwinge, D., Trauner, M., Lohse, A.W., Bonn, S., Hübner, N. and Schramm, C.
JHEP Reports 7
(3): 101267.
March 2025
Inhalation of the novel tryptophan hydroxylase 1 inhibitor TPT-004 alleviates pulmonary arterial hypertension in rats.
Legchenko, E., Chouvarine, P., Hysko, K., Qadri, F., Wesolowski, R., Specker, E., Glage, S., Meier, M., Schwarz, K., Heineke, J., Pohlmann, G., Ramazanoglu, M., Bader, M. and Hansmann, G.
American Journal of Respiratory Cell and Molecular Biology
3 February 2025
(In Press)
Characterization of anthracycline-induced cardiotoxicity by diffusion tensor magnetic resonance imaging.
Lohr, D., Thiele, A., Stahnke, M., Braun, V.M., Klopfleisch, R., Klein, O., Dresen, S., Landmesser, U., Foryst-Ludwig, A., Kintscher, U., Schreiber, L.M. and Beyhoff, N.
Basic Research in Cardiology 120
(1): 57-69.
February 2025
Prognostic value of CD163(+) macrophages in solid tumor malignancies: a scoping review.
Mathiesen, H., Juul-Madsen, K., Tramm, T., Vorup-Jensen, T., Møller, H.J., Etzerodt, A. and Andersen, M.N.
Immunology Letters 272
: 106970.
April 2025
Distinguishing transient from persistent brain structural changes in pediatric patients with acute disseminated encephalomyelitis.
Millward, J.M., Pilgrim, E., Baumann, M., Wendel, E.M., El Naggar, I., Bertolini, A., Bartels, F., Finke, C., Paul, F., Niendorf, T., Rostásy, K. and Waiczies, S.
Neurology Neuroimmunology & Neuroinflammation 12
(1): e200337.
January 2025
Aryl hydrocarbon receptor activation promotes effector CD4(+) T cell homeostasis and restrains salt-sensitive hypertension.
Molina, P.A., Edell, C.J., Dunaway, L.S., Kellum, C.E., Muir, R.Q., Jennings, M.S., Colson, J.C., De Miguel, C., Rhoads, M.K., Buzzelli, A.A., Harrington, L.E., Meza-Perez, S., Randall, T.D., Botta, D., Müller, D.N., Pollock, D.M., Maynard, C.L. and Pollock, J.S.
Function
: zqaf001.
8 January 2025
(In Press)
Socioeconomic characteristics and the home food environment are associated with feeding healthful and discretionary foods during the first year of life in the Pregnancy Eating Attributes Study.
Nansel, T.R., Lipsky, L.M., Schwedhelm, C., Faith, M.S. and Siega-Riz, A.M.
Journal of the Academy of Nutrition and Dietetics 125
(2): 228-238.
February 2025
Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations.
Nishijima, S., Stankevic, E., Aasmets, O., Schmidt, T.S.B., Nagata, N., Keller, M.I., Ferretti, P., Juel, H.B., Fullam, A., Robbani, S.M., Schudoma, C., Hansen, J.K., Holm, L.A., Israelsen, M., Schierwagen, R., Torp, N., Telzerow, A., Hercog, R., Kandels, S., Hazenbrink, D.H.M., Arumugam, M., Bendtsen, F., Brøns, C., Fonvig, C.E., Holm, J.C., Nielsen, T., Pedersen, J.S., Thiele, M.S., Trebicka, J., Org, E., Krag, A., Hansen, T., Kuhn, M. and Bork, P.
Cell 188
(1): 222-236.
9 January 2025
3D metamaterials facilitate human cardiac MRI at 21.0 Tesla: a proof-of-concept study.
Nurzed, B., Saha, N., Millward, J.M. and Niendorf, T.
Sensors 25
(3): 620.
21 January 2025
Divergent endothelial mechanisms drive arteriovenous malformations in ALK1 and SMAD4 loss-of-function.
Oppenheim, O., Giese, W., Park, H., Baumann, E., Ivanov, A., Beule, D., Eichmann, A. and Gerhardt, H.
bioRxiv
: 2025.01.03.631070v2.
6 January 2025
Challenges and opportunities in the clinical translation of high-resolution spatial transcriptomics.
Pentimalli, T.M., Karaiskos, N. and Rajewsky, N.
Annual Review of Pathology : Mechanisms of Disease 20
: 405-432.
January 2025
Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort.
Reichmann, R., Nimptsch, K., Pischon, T., Gunter, M.J., Jenab, M., Eriksen, A.K., Tjonneland, A., Janke, J., Katzke, V., Kaaks, R., Schulze, M.B., Eichelmann, F., Masala, G., Sieri, S., Pasanisi, F., Tumino, R., Giraudo, M.T., Rothwell, J., Severi, G., Jakszyn, P., Sanchez-Perez, M.J., Amiano, P., Colorado-Yohar, S.M., Guevara, M., van Guelpen, B., Aglago, E.K., Heath, A.K., Smith-Byrne, K., Weiderpass, E. and Aleksandrova, K.
International Journal of Cancer 156
(5): 930-942.
1 March 2025
Renal damage-induced hepcidin accumulation contributes to anemia in angiotensinogen-deficient mice.
Rodrigues, A.F., Boreggio, L., Lahuta, T., Qadri, F., Alenina, N., Barros, C.C., Todiras, M. and Bader, M.
Clinical Science
27 January 2025
(In Press)
The non-canonical proteome: a novel contributor to cancer proliferation.
Ruiz-Orera, J. and Hübner, N.
Cell Research
14 January 2025
(In Press)
Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics.
Sakenova, N., Cacace, E., Orakov, A., Huber, F., Varik, V., Kritikos, G., Michiels, J., Bork, P., Cossart, P., Goemans, C.V. and Typas, A.
Nature Microbiology 10
(1): 202-216.
January 2025
Dental and oral health assessments in the German National Cohort (NAKO).
Samietz, S., Borof, K., Hertrampf, K., Aarabi, G., Ciardo, A., Finke, H., Hagenfeld, D., Kühnisch, J., Rütters, M., Baumeister, S.E., Reckelkamm, S.L., Kim, T.S., Kocher, T., Ahrens, W., Brenner, H., Emmel, C., Fischer, B., Führer, A., Greiser, K.H., Grischke, J., Günther, K., Harth, V., Jaskulski, S., Karch, A., Keil, T., Kemmling, Y., Kluttig, A., Krist, L., Kuss, O., Leitzmann, M., Meinke-Franze, C., Michels, K.B., Obi, N., Peters, A., Pischon, N., Pischon, T., Schipf, S., Schmidt, B., Teismann, H., Rupf, S. and Holtfreter, B.
BMC Oral Health 25
(1): 149.
28 January 2025
Protocol for high-resolution 3D spatial transcriptomics using Open-ST.
Schott, M., León-Periñán, D., Splendiani, E., Ferretti, E., Macino, G., Karaiskos, N. and Rajewsky, N.
STAR Protocols 6
(1): 103521.
21 March 2025
Diurnal timing of physical activity in relation to obesity and diabetes in the German National Cohort (NAKO).
Stein, M.J., Weber, A., Bamberg, F., Baurecht, H., Berger, K., Bohmann, P., Brenner, H., Brummer, J., Dörr, M., Fischer, B., Gastell, S., Greiser, K.H., Harth, V., Hebestreit, A., Heise, J.K., Herbolsheimer, F., Ittermann, T., Karch, A., Keil, T., Kluttig, A., Krist, L., Michels, K.B., Mikolajczyk, R., Nauck, M., Nimptsch, K., Obi, N., Pischon, T., Pivovarova-Ramich, O., Schikowski, T., Schmidt, B., Schulze, M.B., Steindorf, K., Zylla, S. and Leitzmann, M.F
International Journal of Obesity
24 January 2025
(In Press)
Expression and function of Connexin 43 and Connexin 37 in the murine zona glomerulosa.
Stölting, G., Hellmig, N., Dinh, H.A., Butz, F., Secener, A.K., Volkert, M. and Scholl, U.I.
Physiological Reports 13
(3): e70215.
February 2025
The STRING database in 2025: protein networks with directionality of regulation.
Szklarczyk, D., Nastou, K., Koutrouli, M., Kirsch, R., Mehryary, F., Hachilif, R., Hu, D., Peluso, M.E., Huang, Q., Fang, T., Doncheva, N.T., Pyysalo, S., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 53
(D1): D730–D737.
6 January 2025
A novel approach to modelling acute cardiac decompensation in rats.
Thiele, A., Bartolomaeus, H., Anandakumar, H., Haase, N., Heuser, A., Müller, D.N., Dechend, R. and Wilck, N.
Cardiovascular Research
: cvae268.
6 January 2025
(In Press)
Protein kinase A regulates ferroptosis by controlling GPX4 m(6)A modification through phosphorylation of ALKBH5.
Zhao, X., Sun, Y., Zou, J., Wu, Y., Huang, M., Kong, H., Liu, G., Gerhardt, H., Gu, W., Zhang, Y., Shang, M. and Wang, X.
Cell Death and Differentiation
3 February 2025
(In Press)
Transgenic rat with ubiquitous expression of angiotensin-(1-7)-producing fusion protein: a new tool to study the role of protective arm of the renin-angiotensin system in the pathophysiology of cardio-renal diseases.
Červenka, L., Husková, Z., Kikerlová, S., Gawrys, O., Vacková, Š., Škaroupková, P., Sadowski, J., Miklovič, M., Molnár, M., Táborský, M., Melenovský, V. and Bader, M.
Hypertension Research 48
(1): 336-352.
January 2025
2024
The gut microbiome strongly mediates the impact of lifestyle combined variables on cardiometabolic phenotypes.
Adriouch, S., Belda, E., Swartz, T.D., Forslund, S., Le Roy, Ti., Prifti, E., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Andrikopoulos, P., Chechi, K., Puig-Castellví, F., Froguel, P., Holmes, B., Alili, R., Andreelli, F., Soula, H., Salem, J.E., Falony, G., Vieira-Silva, S., Galazzo, Gi., Raes, J., Bork, P., Stumvoll, M., Pedersen, O., Ehrlich, S.D., Dumas, M.E., Oppert, J.M., Dao, M.C., Zucker, J.D. and Clément, K.
medRxiv
: 2024.01.12.24301195v2.
17 January 2024
Rigorous science demands support of transgender scientists.
Aghi, K., Anderson, B.M., Castellano, B.M., Cunningham, A., Delano, M., Dickinson, E.S., von Diezmann, L., Forslund-Startceva, S.K., Grijseels, D.M., Groh, S.S., Guthman, E.M., Jayasinghe, I., Johnston, J., Long, S., McLaughlin, J.F., McLaughlin, M., Miyagi, M., Rajaraman, B., Sancheznieto, F., Scheim, A.I., Sun, S.E.D., Titmuss, F.D., Walsh, R.J. and Weinberg, Z.Y.
Cell 187
(6): 1327-1334.
14 March 2024
Calibration-free parallel transmission of the cervical, thoracic, and lumbar spinal cord at 7T.
Aigner, C.S., Sánchez Alarcon, M.F., D'Astous, A., Alonso-Ortiz, E., Cohen-Adad, J. and Schmitter, S.
Magnetic Resonance in Medicine 92
(4): 1496-1510.
October 2024
Donor-derived cell-free DNA monitoring for early diagnosis of antibody-mediated rejection after kidney transplantation: a randomized trial.
Akifova, A., Budde, K., Amann, K., Buettner-Herold, M., Choi, M., Oellerich, M., Beck, J., Bornemann-Kolatzki, K., Schütz, E., Bachmann, F., Halleck, F., von Hoerschelmann, E., Koch, N., Schrezenmeier, E., Seelow, E., Waiser, J., Zukunft, B., Eckardt, K.U., Halbritter, J., Kettritz, R., Del Moral, C.L., Lachmann, N., Stauch, D., Niemann, M., Schmidt, D., Halloran, P.F. and Osmanodja, B.
Nephrology Dialysis Transplantation
29 November 2024
(In Press)
Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, O., Sünkel, C., Blanc, E., Catar, R.A., Ashraf, M.I., Zhao, H., Wang, P., Rinschen, M.M., Fritsche-Guenther, R., Grahammer, F., Bachmann, S., Beule, D., Kirwan, J.A., Rajewsky, N., Huber, T.B., Gürgen, D. and Kusch, A.
Biology of Sex Differences 15
(1): 72.
15 September 2024
Cardiovascular multimodality imaging in women: a scientific statement of the European Association of Cardiovascular Imaging (EACVI) of the ESC.
Almeida, A.G., Grapsa, J., Gemelli, A., Bucciarelli-Ducci, C., Gerber, B., Ajmone-Marsan, N., Bernard, A., Donal, E., Dweck, M.R, Haugaa, K.H., Hristova, K., Maceira, A., Mandoli, G.E., Mulvagh, S., Morrone, D., Plonska-Gosciniak, E., Sade, L.E., Schivalkar, B., Schulz-Menger, J., Shaw, L., Sitges, M., von Kemp, B., Pinto, F.J., Edvardsen, T., Petersen, S.E. and Cosyns, B.
European Heart Journal - Cardiovascular Imaging 25
(4): e116-e136.
April 2024
Poor decision making and sociability impairment following central serotonin reduction in inducible TPH2-knockdown rats.
Alonso, L., Peeva, P., Fernández-del Valle Alquicira, T., Erdelyi, N., Gil Nolskog, Á., Bader, M., Winter, Y., Alenina, N. and Rivalan, M.
International Journal of Molecular Sciences 25
(9): 5003.
May 2024
Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors.
Amado Costa, L., Oliveira Amaral, L.B., Mourão, F.A.G., Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Hormones and Behavior 163
: 105551.
27 April 2024
A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on pulmonary circulation & right ventricular function.
Ameri, P., Mercurio, V., Pollesello, P., Anker, M.S., Backs, Jo., Bayes-Genis, A., Borlaug, B.A., Burkhoff, D., Caravita, S., Chan, S.Y., de Man, F., Giannakoulas, G., González, A., Guazzi, M., Hassoun, P.M., Hemnes, A.R., Maack, C., Madden, B., Melenovsky, V., Müller, O.J., Papp, Z., Pullamsetti, S.S., Rainer, P.P., Redfield, M.M., Rich, S., Schiattarella, G.G., Skaara, H., Stellos, K., Tedford, R.J., Thum, T., Vachiery, J.L., van der Meer, P., Van Linthout, S., Pruszczyk, P., Seferovic, P., Coats, A.J.S., Metra, M., Rosano, G., Rosenkranz, S. and Tocchetti, C.G.
European Journal of Heart Failure 26
(4): 707-729.
April 2024
Segmental patterning of microbiota and immune cells in the murine intestinal tract.
Anandakumar, H., Rauch, A., Wimmer, M.I., Yarritu, A., Koch, G., McParland, V., Bartolomaeus, H. and Wilck, N.
Gut Microbes 16
(1): 2398126.
2024
Rapid MR elastography of the liver for subsecond stiffness sampling.
Anders, M., Meyer, T., Warmuth, C., Pfeuffer, J., Tzschaetzsch, H., Herthum, H., Shahryari, M., Degenhardt, K., Wieben, O., Schmitter, S., Schulz-Menger, J., Schaeffter, T., Braun, J. and Sack, I.
Magnetic Resonance in Medicine 91
(1): 312-324.
January 2024
Identification and Mitigation of microbial contaminant reads from long-read metagenomic samples.
Ayala-Montano, S., Afolayan, A.O., Kociurzynski, R., Loeber, U. and Reuter, S.
bioRxiv
: 2024.11.26.625374v1.
1 December 2024
ADAM19 cleaves the PTH receptor and associates with brachydactyly type E.
Aydin, A., Klenk, C., Nemec, K., Işbilir, Ali, Martin, L.M., Zauber, H., Rrustemi, T., Toka, H.R., Schuster, H., Gong, M., Stricker, S., Bock, A., Bähring, S., Selbach, M., Lohse, M.J. and Luft, F.C.
Life Science Alliance 7
(4): e202302400.
April 2024
High-sensitivity cardiac troponin I enhances preeclampsia prediction beyond maternal factors and the sFlt-1/PlGF ratio.
Bacmeister, L., Goßling, A., Buellesbach, A., Birukov, A., Myers, J.E., Thomas, S.T., Lee, S., Andersen, M.S., Jorgensen, J.S., Diemert, A., Blois, S.M., Arck, P.C., Hecher, K., Herse, F., Blankenberg, S., Dechend, R., Westermann, D. and Zeller, T.
Circulation 149
(2): 95-106.
9 January 2024
Alternative renin-angiotensin system.
Bader, M., Muscha Steckelings, U., Alenina, N., Santos, R.A.S. and Ferrario, C.M.
Hypertension 81
(5): 964-976.
May 2024
Baseline MRI examination in the NAKO health study - findings on feasibility, participation and dropout rates, comfort, and image quality.
Bamberg, F., Schlett, C.L., Caspers, S., Ringhof, S., Günther, M., Hirsch, J.G., Rüdebusch, J., Miklánková, P., Bittner, N., Jockwitz, C., Forsting, M., Hosten, N., Kaaks, R., Kauczor, H.U., Kroenke, T., Niendorf, T., Peters, A., Pischon, T., Stang, A., Berger, K. and Völzke, H.
Deutsches Arzteblatt International 121
(18): 587-593.
6 September 2024
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) is reduced with preeclampsia and small for gestational aged fetuses.
Bartho, L.A., Walker, S.P., Cannon, P., Nguyen, T.V., Nguyen, A., Botha, S.M., Hannan, N.J., Tong, S. and Kaitu'u-Lino, T.J.
Placenta 156
: 10-13.
October 2024
Gut-immune axis and cardiovascular risk in chronic kidney disease.
Behrens, F., Bartolomaeus, H., Wilck, N. and Holle, J.
Clinical Kidney Journal 17
(1): sfad303.
January 2024
A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction.
Bender, R.H.F., O'Donnell, B.T., Shergill, B., Pham, B.Q., Tahmouresie, S., Sanchez, C.N., Juat, D.J., Hatch, M.M.S., Shirure, V.S., Wortham, M., Nguyen-Ngoc, K.V., Jun, Y., Gaetani, R., Christman, K.L., Teyton, L., George, S.C., Sander, M. and Hughes, C.C.W.
Biofabrication 16
(2): 025001.
11 January 2024
High-resolution DNA methylation changes reveal biomarkers of heart failure with preserved ejection fraction versus reduced ejection fraction.
Benincasa, G., Pepin, M.E., Russo, V., Cacciatore, F., D'Alto, M., Argiento, P., Romeo, E., Chiappetti, R., Laezza, N., Wende, A.R., Schiattarella, G.G., Coscioni, E., La Montagna, A., Amarelli, C., Maiello, C., Golino, P., Condorelli, G. and Napoli, C.
Basic Research in Cardiology
27 December 2024
(In Press)
SoccHealth: a health status examination of former professional football (soccer) players within the German National Cohort.
Berger, K., Baurecht, H., Stein, M., Heise, J.K., Castell, S., Weisser, L., Schikowski, T., Oliver, K., Lieb, W., Micolajczyk, R., Kluttig, A., Schmitt, B., Stang, A., Pischon, T., Peters, A., Brenner, H., Leitzmann, M., Krist, L., Keil, T., Karch, A. and Meyer, T.
BMJ Open Sport & Exercise Medicine 10
(4): e002228.
1 October 2024
Association of adverse clinical outcomes with peri-infarct ischemia detected by stress cardiac magnetic imaging.
Bernhard, B., Ge, Y., Antiochos, P., Heydari, B., Islam, S., Sanchez Santiuste, N., Steel, K.E., Bingham, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Shanbhag, S.M., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Raman, S.V., Ferrari, V.A., Shah, D.J., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
Journal of the American College of Cardiology 84
(5): 417-429.
30 July 2024
Oral microbiota of patients with phenylketonuria: a nation-based cross-sectional study.
Bingöl, M., Cardilli, A., Bingöl, A.C., Löber, U., Bang, C., Franke, A., Bartzela, T., Beblo, S., Mönch, E., Stolz, S., Schaefer, A.S., Forslund, S.K. and Richter, G.M.
Journal of Clinical Periodontology 51
(8): 1081-1092.
August 2024
Amplification of autoimmune organ damage by NKp46-activated ILC1.
Biniaris-Georgallis, S.I., Aschman, T., Stergioula, K., Schreiber, F., Jafari, V., Taranko, A., Karmalkar, T., Kasapi, A., Lenac Rovis, T., Jelencic, V., Bejarano, D.A., Fabry, L., Papacharalampous, M., Mattiola, I., Molgora, M., Hou, J., Hublitz, K.W., Heinrich, F., Guerra, G.M., Durek, P., Patone, G., Lindberg, E.L.H., Maatz, H., Hölsken, O., Krönke, G., Mortha, A., Voll, R.E., Clarke, A.J., Hauser, A.E., Colonna, M., Thurley, K., Schlitzer, A., Schneider, C., Stamatiades, E.G., Mashreghi, M.F., Jonjic, S., Hübner, N., Diefenbach, A., Kanda, M. and Triantafyllopoulou, A.
Nature 634
(8035): 952-960.
24 October 2024
Microbiome dynamics and functional composition in Coelopa frigida (Diptera, Coelopidae): insights into trophic specialization of kelp flies.
Bischof, P.S.P., Bartolomaeus, T.U.P., Löber, U. and Bleidorn, C.
Microbial Ecology 87
(1): 91.
3 July 2024
Endothelial overexpression of TGF-β-induced protein impairs venous thrombus resolution.
Bochenek, M.L., Saar, K., Nazari-Jahantigh, M., Gogiraju, R., Wiedenroth, C.B., Münzel, T., Mayer, E., Fink, L., Schober, A., Hübner, N., Guth, S., Konstantinides, S. and Schäfer, K.
JACC: Basic to Translational Science 9
(1): 100-116.
January 2024
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications.
Bode, D., Pronto, J.R.D., Schiattarella, G.G. and Voigt, N.
Nature Reviews Cardiology 21
(10): 682-700.
October 2024
Dietary protein and blood pressure: an umbrella review of systematic reviews and evaluation of the evidence.
Boeing, H., Amini, A.M., Haardt, J., Schmidt, A., Bischoff-Ferrari, H.A., Buyken, A.E., Egert, S., Ellinger, S., Kroke, A., Lorkowski, S., Louis, S., Nimptsch, K., Schulze, M.B., Schutkowski, A., Schwingshackl, L., Siener, R., Zittermann, A., Watzl, B. and Stangl, G.I.
European Journal of Nutrition 63
(4): 1041-1058.
June 2024
Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N., Bader, M., Willnow, T.E., Wiedenmann, B. and Sigal, M.
Frontiers in Endocrinology 15
: 1331231.
17 April 2024
Transient stabilization of human cardiovascular progenitor cells from human pluripotent stem cells in vitro reflects stage-specific heart development in vivo.
Bolesani, E., Bornhorst, D., Iyer, L.I., Zawada, D., Friese, N., Morgan, M., Lange, L., Gonzalez, D., Schrode, N., Leffler, A., Wunder, J., Franke, A., Drakhlis, L., Sebra, R., Schambach, A., Goedel, A., Dubois, N., Dobreva, G., Moretti, A., Zelarayán, L.C., Abdelilah-Seyfried, S. and Zweigerdt, R.
Cardiovascular Research 120
(11): 1295-1311.
July 2024
Adiposity influences on myocardial deformation: a cardiovascular magnetic resonance feature tracking study in people with overweight to obesity without established cardiovascular disease.
Bolz, C., Blaszczyk, E., Mayr, T., Lim, C., Haufe, S., Jordan, J., Barckow, P., Gröschel, J. and Schulz-Menger, J.
International Journal of Cardiovascular Imaging 40
(3): 643-654.
March 2024
Cognitive reserve and the risk of postoperative neurocognitive disorders in older age.
Borchers, F., Rumpel, M., Laubrock, J., Spies, C., Kozma, P., Slooter, A., van Montfort, S.J.T., Piper, S.K., Wiebach, J., Winterer, G., Pischon, T. and Feinkohl, I.
Frontiers in Aging Neuroscience 15
: 1327388.
5 February 2024
Inheritance of old mitochondria controls early CD8(+) T cell fate commitment and is regulated by autophagy.
Borsa, M., Lechuga-Vieco, A.V., Kayvanjoo, A.H., Yazicioglu, Y., Compeer, E.B., Richter, F.C., Bui, H., Dustin, M.L., Katajisto, P. and Simon, A.K.
bioRxiv
: 2024.01.29.577412.
31 January 2024
Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.
Borsa, M., Obba, S., Richter, F.C., Zhang, H., Riffelmacher, T., Carrelha, J., Alsaleh, G., Jacobsen, S.E.W. and Simon, A.K.
Autophagy 20
(1): 45-57.
January 2024
Functional autoantibodies against G protein-coupled receptors in hepatic and pulmonary hypertensions in human schistosomiasis.
Botoni, F.A., Lambertucci, J.R., Santos, R.A.S., Müller, J., Talvani, A. and Wallukat, G.
Frontiers in Immunology 15
: 1404384.
17 June 2024
Diet and physical activity as risk-reducing factors for hidradenitis suppurativa.
Bouwman, K., Moazzen, S., Kroah-Hartman, M., Dijkstra, G., Horváth, B. and Alizadeh, B.Z.
Journal of the European Academy of Dermatology and Venereology 38
(5): 910-919.
May 2024
Fasting in science and clinics - a report on proceedings from the International Scientific Symposium and Conference on Fasting in Berlin (June 2023).
Breinlinger, C., Meiß, S., Hanslian, E., Jordan, St., Boschmann, M., Rajput Khokhar, A., Michalsen, A. and Koppold, D.A.
Complementary Medicine Research 31
(5): 484-491.
October 2024
Epidemiology of myocarditis following COVID-19 or influenza and use of diagnostic assessments.
Butler, O., Raisi-Estabragh, Z., Han, Y., Frenz, A.K., Harz, C., Kelle, S., Schulz-Menger, J., Michel, A. and Kim, J.
Open Heart 11
(2): e002947.
9 November 2024
Microproteins encoded by noncanonical ORFs are a major source of tumor-specific antigens in a liver cancer patient meta-cohort.
Camarena, M.E., Theunissen, P., Ruiz, M., Ruiz-Orera, J., Calvo-Serra, B., Castelo, R., Castro, C., Sarobe, P., Fortes, P., Perera-Bel, J. and Albà, M.M.
Science Advances 10
(28): eadn3628.
July 2024
Intramyocardial sprouting tip cells specify coronary arterialization.
Cano, E., Schwarzkopf, J., Kanda, M., Lindberg, E.L., Hollfinger, I., Pogontke, C., Braeuning, C., Fischer, C., Hübner, N. and Gerhardt, H.
Circulation Research 135
(6): 671-684.
30 August 2024
Hyperphenylalaninemia and serotonin deficiency in Dnajc12-deficient mice.
Cao, Y., Popp, O., Milani, N., Qadri, F., Kühn, R., Mertins, P., Bader, M. and Alenina, N.
Communications Biology 7
(1): 1641.
18 December 2024
Beyond weight loss: the emerging role of incretin-based treatments in cardiometabolic HFpEF.
Capone, F., Nambiar, N. and Schiattarella, G.G.
Current Opinion in Cardiology 39
(2): 148-153.
May 2024
SRRM2 splicing factor modulates cell fate in early development.
Carvalho, S., Zea-Redondo, L., Tang, T.C.C., Stachel-Braum, P., Miller, D., Caldas, P., Kukalev, A., Diecke, S., Grosswendt, S., Grosso, A.R. and Pombo, A.
Biology Open 13
(4): bio060415.
April 2024
miR-7 controls glutamatergic transmission and neuronal connectivity in a Cdr1as-dependent manner.
Cerda Jara, C.A., Kim, S.J., Thomas, G., Farsi, Z., Zolotarov, G., Dube, G., Deter, A., Bahry, E., Georgii, E., Woehler, A., Piwecka, M. and Rajewsky, N.
EMBO Reports 25
(7): 3039.
July 2024
Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome.
Chan, J.C., Alenina, N., Cunningham, A.M., Ramakrishnan, A., Shen, Li, Bader, M. and Maze, I.
Journal of Molecular Biology 436
(7): 168454.
1 April 2024
Baseline microbiome composition impacts resilience to and recovery following antibiotics.
Chen, C.Y., Löber, U., Bartolomaeus, H., Maier, L., Müller, D.N., Wilck, N., Jarquín-Díaz, V.H. and Forslund-Startceva, S.K.
bioRxiv
: 2024.03.31.587491.
31 March 2024
Efficient recovery of complete gut viral genomes by combined short- and long-read sequencing.
Chen, J., Sun, C., Dong, Y., Jin, M., Lai, S., Jia, L., Zhao, X., Wang, H., Gao, N.L., Bork, P., Liu, Z., Chen, W.H. and Zhao, X.M.
Advanced Science 11
(13): 2305818.
3 April 2024
Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells.
Chiariello, A.M., Abraham, Alex, Bianco, S., Esposito, A., Fontana, A., Vercellone, F., Conte, M. and Nicodemi, M.
Nature Communications 15
(1): 4014.
13 May 2024
Protocol for assessing myogenic tone and perfusion pressure in isolated mouse kidneys.
Chu, Z., Kassmann, M., Anistan, Y.M., Luft, F.C., Gollasch, M. and Tsvetkov, D.
STAR Protocols 5
(1): 102845.
15 March 2024
Proposed diagnostic criteria for arrhythmogenic cardiomyopathy. European Task Force consensus report.
Corrado, D., Anastasakis, A., Basso, C., Bauce, B., Blomström-Lundqvist, C., Bucciarelli-Ducci, C., Cipriani, A., De Asmundis, C., Gandjbakhch, E., Jiménez-Jaimez, J., Kharlap, M., McKenna, W.J., Monserrat, L., Moon, J., Pantazis, A., Pelliccia, A., Perazzolo Marra, M., Pillichou, K., Schulz-Menger, J., Jurcut, R., Seferovic, P., Sharma, S., Tfelt-Hansen, J., Thiene, G., Wichter, T., Wilde, A. and Zorzi, A.
International Journal of Cardiology 395
: 131447.
15 January 2024
Next questions in autophagy.
Cuervo, A.M., Elazar, Z., Evans, C., Ge, L., Hansen, M., Jäättelä, M., Liang, J.R.A., Loos, B., Mizushima, N., Simon, A.K., Tooze, S., Yoshimori, T. and Nakamura, S.
Nature Cell Biology 26
(5): 661-666.
May 2024
Genomic attributes of airway commensal bacteria and mucosa.
Cuthbertson, L., Löber, U., Ish-Horowicz, J.S., McBrien, C.N., Churchward, C., Parker, J.C., Olanipekun, M.T., Burke, C., McGowan, A., Davies, G.A., Lewis, K.E., Hopkin, J.M., Chung, K.F., O'Carroll, O., Faul, J., Creaser-Thomas, J., Andrews, M., Ghosal, R., Piatek, S., Willis-Owen, S.A.G., Bartolomaeus, T.U.P., Birkner, T., Dwyer, S., Kumar, N., Turek, E.M., William Musk, A, Hui, J., Hunter, M., James, A., Dumas, M.E., Filippi, S., Cox, M.J., Lawley, T.D., Forslund, S.K., Moffatt, M.F. and Cookson, W.O.C.
Communications Biology 7
(1): 171.
12 February 2024
Toward accurate and fast velocity quantification with 3D ultrashort TE phase-contrast imaging.
Degenhardt, K., Schmidt, S., Aigner, C.S., Kratzer, F.J., Seiter, D.P., Mueller, M., Kolbitsch, C., Nagel, A.M., Wieben, O., Schaeffter, T., Schulz-Menger, J. and Schmitter, S.
Magnetic Resonance in Medicine 91
(5): 1994-2009.
May 2024
An integrated view of the structure and function of the human 4D nucleome.
Dekker, J., Oksuz, B.A., Zhang, Y., Wang, Y., Minsk, M.K., Kuang, S., Yang, L., Gibcus, J.H., Krietenstein, N., Rando, O., Xu, J., Janssens, D.H., Henikoff, S., Kukalev, A., Willemin, A., Winick-Ng, W., Kempfer, R., Pombo, A., Yu, M., Kumar, P., Zhang, L., Belmont, A.S., Sasaki, T., van Schaik, T., Brueckner, L., Peric-Hupkes, D., van Steensel, B., Wang, P., Chai, H., Kim, M., Ruan, Y., Zhang, R., Quinodoz, S.A., Bhat, P., Guttman, M., Zhao, W., Chien, S., Liu, Y., Venev, S.V., Plewczynski, D., Irastorza Azcarate, I., Szabo, D., Thieme, C.J., Szczepinska, T., Chilinski, M., Sengupta, K., Conte, M., Esposito, A., Abraham, A., Zhang, R., Wang, Y., Wen, X., Wu, Q., Yang, Y., Liu, J., Boninsegna, L., Yildirim, A., Zhan, Y., Chiariello, A.M., Bianco, S., Lee, L., Hu, M., Li, Y., Barnett, R.., Cook, A.L., Emerson, D.J., Marchal, C., Zhao, P., Park, P., Alver, B.H., Schroeder, A., Navelkar, R., Bakker, C., Ronchetti, W., Ehmsen, S., Veit, A., Gehlenborg, N., Wang, T., Li, D., Wang, X., Nicodemi, M., Ren, B., Zhong, S., Phillips-Cremins, J.E., Gilbert, D.M., Pollard, K.S., Alber, F., Ma, J., Noble, W.S. and Yue, F.
bioRxiv
: 2024.09.17.613111v2.
27 October 2024
High-quality peptide evidence for annotating non-canonical open reading frames as human proteins.
Deutsch, Eric W, Kok, Leron W, Mudge, Jonathan M, Ruiz-Orera, J., Fierro-Monti, Ivo, Sun, Zhi, Abelin, Jennifer G, Alba, M Mar, Aspden, Julie L, Bazzini, Ariel A, Bruford, Elspeth, Brunet, Marie A, Calviello, L., Carr, Steven A, Carvunis, Anne-Ruxandra, Chothani, Sonia, Clauwaert, Jim, Dean, Kellie, Faridi, Pouya, Frankish, Adam, Hubner, N., Ingolia, Nicholas, Magrane, Michele, Martin, Maria Jesus, Martinez, Thomas F, Menschaert, Gerben, Ohler, U., Orchard, Sandra, Rackham, Owen, Roucou, Xavier, Slavoff, Sarah A, Valen, Eivind, Wacholder, Aaron C, Weissman, Jonathan S., Wu, Wei, Xie, Zhi, Choudhary, Jyoti, Bassani-Sternberg, Michal, Vizcaino, Juan Antonio, Ternette, Nicola, Moritz, Robert L., Prensner, John and van Heesch, S.
bioRxiv
: 2024.09.09.612016.
9 September 2024
Pharmacological inhibition of cathepsin S and of NSPs-AAP-1 (a novel, alternative protease driving the activation of neutrophil serine proteases).
Domain, R., Seren, S., Jerke, U., Makridakis, M., Chen, K.J., Zoidakis, J., Rhimi, M., Zhang, X., Bonvent, T., Croix, C., Gonzalez, L., Li, D., Basso, J., Paget, C., Viaud-Massuard, M.C., Lalmanach, G., Shi, G.P., Aghdassi, A., Vlahou, A., McDonald, P.P., Couillin, I., Williams, R., Kettritz, R. and Korkmaz, B.
Biochemical Pharmacology 229
: 116114.
November 2024
Operating and biocontainment procedures of a facility for laboratory mice with a natural microbiome: immunophenotyping procedure.
Drude, N., Diederich, K., Duerr, C.U., Haase, N., Harms, C., Heppner, F., Jendrach, M., Kahnau, P., Kolesnichenko, M., Lewejohann, L., Kurreck, C., Lohan, A., Mall, M.A., Müller, D., Nagel-Riedasch, S., Opitz, B., Schaupp, L., Schönfelder, G., Weber, A., Willimsky, G., Zang, Y., Rosshart, S.P., Diefenbach, A. and Jordan, S.
Journal of Visualized Experiments
(214): e67100.
13 December 2024
A catalog of small proteins from the global microbiome.
Duan, Y., Santos-Júnior, C.D., Schmidt, T.S., Fullam, A., de Almeida, B.L.S., Zhu, C., Kuhn, M., Zhao, X.M., Bork, P. and Coelho, L.P.
Nature Communications 15
(1): 7563.
31 August 2024
Prospects for leveraging the microbiota as medicine for hypertension.
Durgan, D.J., Zubcevic, J., Vijay-Kumar, M., Yang, T., Manandhar, I., Aryal, S., Muralitharan, R.R., Li, H.B., Li, Y., Abais-Battad, J.M., Pluznick, J.L., Muller, D.N., Marques, F.Z. and Joe, B.
Hypertension 81
(5): 951-963.
May 2024
Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice.
Dörmann, N., Hammer, E., Struckmann, K., Rüdebusch, J., Bartels, K., Wenzel, K., Schulz, J., Gross, S., Schwanz, S., Martin, E., Fielitz, B., Pablo Tortola, C., Hahn, A., Benkner, A., Völker, U., Felix, S.B and Fielitz, J.
Frontiers in Cardiovascular Medicine 10
: 1323760.
8 January 2024
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner, P.J., Anandakumar, H., Röwekamp, I., Fiocca Vernengo, F., Millet Pascual-Leone, B., Krzanowski, M., Sellmaier, J., Brüning, U., Fritsche-Guenther, R., Pfannkuch, L., Kurth, F., Milek, M., Igbokwe, V., Löber, U., Gutbier, B., Holstein, M., Heinz, G.A., Mashreghi, M.F., Schulte, L.N., Klatt, A.B., Caesar, S., Wienhold, S.M., Offermanns, S., Mack, M., Witzenrath, M., Jordan, S., Beule, D., Kirwan, J.A., Forslund, S.K., Wilck, N., Bartolomaeus, H., Heimesaat, M.M. and Opitz, B.
Nature Communications 15
(1): 2788.
30 March 2024
Effects of a short-term vegan challenge in older adults on metabolic and inflammatory parameters - a randomized controlled crossover study.
Döschner, L., Schulze, K., Göger, L., Bosy-Westphal, A., Krüger, N., Franz, K., Müller-Werdan, U., Herpich, C. and Norman, K.
Molecular Nutrition & Food Research 68
(4): e2300623.
February 2024
Targeted perturb-seq reveals EGR1 and FOS as key regulators of the transcriptional RAF-MAPK response.
El Kassem, G., Sieber, A., Klinger, B., Uhlitz, F., Steinbrecht, D., van Bentum, M., Hillmer, J., von Schlichting, J., Schäfer, R., Blüthgen, N. and Boettcher, M.
bioRxiv
: 2024.01.13.575500.
15 January 2024
Protein intake and body weight, fat mass and waist circumference: an umbrella review of systematic reviews for the evidence-based guideline on protein intake of the German Nutrition Society.
Ellinger, S., Amini, A.M., Haardt, J., Lehmann, A., Schmidt, A., Bischoff-Ferrari, H.A., Buyken, A.E., Kroke, A., Kühn, T., Louis, S., Lorkowski, S., Nimptsch, K., Schulze, M.B., Schwingshackl, L., Siener, R., Stangl, G.I., Volkert, D., Zittermann, A., Watzl, B. and Egert, S.
European Journal of Nutrition 63
(1): 3-32.
February 2024
Insulin secretion defect in children and adolescents with obesity: clinical and molecular genetic characterization.
Enders-Seidlitz, H., Raile, K., Gong, M., Galler, A., Kuehnen, P. and Wiegand, S.
Journal of Diabetes Research 2024
: 5558634.
20 March 2024
The evolving landscape of cardiometabolic diseases.
Eroglu, T., Capone, F. and Schiattarella, G.G.
EBioMedicine 109
: 105447.
November 2024
Intermuscular adipose tissue accumulation is associated with higher tissue sodium in healthy individuals.
Ertuglu, L.A., Sahinoz, M., Alsouqi, A., Deger, S.M., Guide, A., Pike, M., Robinson-Cohen, C., Akwo, E., Pridmore, M., Crescenzi, R., Madhur, M.S., Kirabo, A., Harrison, D.G., Luft, F.C., Titze, J., Ikizler, T.A. and Gamboa, J.L.
Physiological Reports 12
(13): e16127.
July 2024
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19.
Essex, M., Millet Pascual-Leone, B.L., Löber, U., Kuhring, M., Zhang, B., Brüning, U., Fritsche-Guenther, R., Krzanowski, M., Fiocca Vernengo, F., Brumhard, S., Röwekamp, I., Bielecka, A.A., Lesker, T.R., Wyler, E., Landthaler, M., Mantei, A., Meisel, C., Caesar, S., Thibeault, C., Corman, V.M., Marko, L., Suttorp, N., Strowig, T., Kurth, F., Sander, L.E., Li, Y., Kirwan, J.A., Forslund, S.K. and Opitz, B.
NPJ Biofilms and Microbiomes 10
(1): 66.
1 August 2024
Shared and distinct gut microbiota in spondyloarthritis, acute anterior uveitis, and Crohn's disease.
Essex, M., Rios Rodriguez, V., Rademacher, J., Proft, F., Löber, U., Marko, L., Pleyer, U., Strowig, T., Marchand, J., Kirwan, J.A., Siegmund, B., Forslund, S.K. and Poddubnyy, D.
Arthritis & Rheumatology 76
(1): 48-58.
January 2024
The diversity of the microbiome impacts chronic lymphocytic leukemia development in mice and humans.
Faitova, T., Coelho, M., Da Cunha-Bang, C., Ozturk, S., Kartal, E., Bork, P., Seiffert, M. and Niemann, C.U.
Haematologica 109
(10): 3237-3250.
October 2024
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
Fasciani, I., Petragnano, F., Wang, Z., Edwards, R., Telugu, N., Pietrantoni, I., Zabel, U., Zauber, H., Grieben, M., Terzenidou, M.E., Di Gregorio, J., Pellegrini, C., Santini, S., Taddei, A.R., Pohl, B., Aringhieri, S., Carli, M., Aloisi, G., Marampon, F., Charlesworth, E., Roman, A., Diecke, S., Flati, V., Giorgi, F., Amicarelli, F., Tobin, A.B., Scarselli, M., Tokatlidis, K., Rossi, M., Lohse, M.J., Annibale, P. and Maggio, R.
PLoS Biology 22
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29 April 2024
Determinants of ascending aortic morphology: Cross-sectional deep learning-based analysis on 25,073 non-contrast-enhanced MRI of NAKO.
Fay, L., Hepp, T., Winkelmann, M.T., Peters, A., Heier, M., Niendorf, T., Pischon, T., Endemann, B., Schulz-Menger, J., Krist, L., Schulze, M.B., Mikolajczyk, R., Wienke, A., Obi, N., Silenou, B.C., Lange, B., Kauczor, H.U., Lieb, W., Baurecht, H., Leitzmann, M., Trares, K., Brenner, H., Michels, K.B., Jaskulski, St., Völzke, H., Nikolaou, K., Schlett, C.L., Bamberg, F., Lescan, M., Yang, B., Küstner, T. and Gatidis, S.
medRxiv
: 2024.07.12.24310356.
15 July 2024
The association of plasma leptin, soluble leptin receptor and total and high-molecular weight adiponectin with the risk of perioperative neurocognitive disorders.
Feinkohl, I., Janke, J., Slooter, A.J.C., Winterer, G., Spies, C. and Pischon, T.
American Journal of Geriatric Psychiatry 32
(9): 1119-1129.
September 2024
Cardiovascular magnetic resonance reveals myocardial involvement in patients with active stage of inflammatory bowel disease.
Fenski, M., Abazi, E., Gröschel, J., Hadler, T., Kappelmayer, D., Kolligs, F., Prieto, C., Botnar, R., Kunze, K.P. and Schulz-Menger, J.
Clinical Research in Cardiology
5 August 2024
(In Press)
Eco-evolutionary dynamics of host - microbiome interactions in a natural population of closely related mouse subspecies and their hybrids.
Ferreira, S.C.M., Jarquín-Díaz, V.H., Planillo, A., Ďureje, L., Martincová, I., Kramer-Schadt, S., Forslund-Startceva, S.K. and Heitlinger, E.
Proceedings of the Royal Society of London Series B-Biological Sciences 291
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December 2024
Role of kinin receptors in skin pigmentation.
Ferreira, J.C.P., Soley, B.S., Pawloski, P.L., Moreira, C.G., Pesquero, J.B., Bader, M., Calixto, J.B., Cabrini, D.A. and Otuki, M.F.
European Journal of Pharmacology 973
: 176537.
15 June 2024
Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients.
Fislage, M., Winzeck, S., Woodrow, R., Lammers-Lietz, F., Stamatakis, E.A., Correia, M.M., Preller, J., Feinkohl, I., Hendrikse, J., Pischon, T., Spies, C.D., Slooter, A.J.C., Winterer, G., Menon, D.K. and Zacharias, N.
Alzheimer's and Dementia 20
(4): 2861-2872.
April 2024
L-glyceraldehyde inhibits neuroblastoma cell growth via a
multi-modal mechanism on metabolism and Signaling.
Forbes, M., Kempa, R., Mastrobuoni, G., Rayman, L., Pietzke, M., Bayram, S., Arlt, B., Spruessel, A., Deubzer, H.E. and Kempa, S.
Cancers 16
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May 2024
Mitophagy modulation for the treatment of cardiovascular diseases.
Forte, M., D'Ambrosio, L., Schiattarella, G.G., Salerno, N., Perrone, M.A., Loffredo, F.S., Bertero, E., Pilichou, K., Manno, G., Valenti, V., Spadafora, L., Bernardi, M., Simeone, B., Sarto, G., Frati, G., Perrino, C. and Sciarretta, S.
European Journal of Clinical Investigation 54
(8): e14199.
August 2024
Effects of bradykinin B2 receptor ablation from tyrosine hydroxylase cells on behavioral and motor aspects in male and female mice.
Franco, T.M., Tavares, M.R., Novaes, L.S., Munhoz, C.D., Peixoto-Santos, J.E., Araujo, R.C., Donato, J., Bader, M. and Wasinski, F.
International Journal of Molecular Sciences 25
(3): 1490.
25 January 2024
Activation mapping in multi-center rat sensory-evoked functional MRI datasets using a unified pipeline.
Galteau, M.E., Broadwater, M., Chen, Y., Desrosiers-Gregoire, G., Gil, R., Kaesser, J., Kim, E., Kiryagdi, P., Lambers, H., Liu, Y.Y., Lopez-Gil, X., MacNicol, E., Mohebkhodaei, P., De Oliveira, R.X.N., Pereira, C.A., Reimann, H.M., Rivera-Olvera, Al., Selingue, E., Sirmpilatze, N., Strobelt, S., Sumiyoshi, A., Tham, C., Tudela, R., Vrooman, R.M., Wank, I., Zhang, Y., van Engelenburg, W.A., Baudewig, J., Boretius, S., Cash, D., Chakravarty, M.M., Chuang, K.H., Ciobanu, L., Devenyi, G.A., Faber, C., Hess, A., Homberg, J.R., Jelescu, I.O., Justicia, C., Kawashima, R., Niendorf, T., Scheenen, T.W.J., Shemesh, N., Soria, G., Todd, N., Wachsmuth, L., Yu, X., Zhang, B.B., Shih, Y.Y.I., Lee, S.H. and Grandjean, J.
bioRxiv
: 2024.09.27.615384.
30 September 2024
YAP/TAZ signaling in allantois-derived cells is required for placental vascularization.
Gao, S., Thillaikumaran, T., Dominguez, M.H., Giang, W., Hayes, K., Chen, X., Pace, J., Bockman, J., Jathan, D., Sung, D., Narayan, S., Frankfurter, M., Mericko-Ishizuka, P., Yang, J., Castro, M., Potente, M. and Kahn, M.L.
bioRxiv
: 2024.09.15.613151.
16 September 2024
iSuRe-HadCre is an essential tool for effective conditional genetics.
Garcia-Gonzalez, I., Rocha, S.F., Hamidi, A., Garcia-Ortega, L., Regano, A., Sanchez-Muñoz, M.S., Lytvyn, M., Garcia-Cabero, A., Roig-Soucase, S., Schoofs, H., Castro, M., Sabata, H., Potente, M., Graupera, M., Makinen, T. and Benedito, R.
Nucleic Acids Research 52
(13): e56.
22 July 2024
Emergence of community behaviors in the gut microbiota upon drug treatment.
Garcia-Santamarina, S., Kuhn, M., Devendran, S., Maier, L., Driessen, M., Mateus, A., Mastrorilli, E., Brochado, A.R., Savitski, M.M., Patil, K.R., Zimmermann, M., Bork, P. and Typas, A.
Cell 187
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31 October 2024
Mechanical strain activates planar cell polarity signaling to coordinate vascular cell dynamics.
Golbach, L., Saha, T., Odenthal-Schnittler, M., Lücking, J., Velic, A., Akmeric, E.B., Bornhorst, D., Popp, O., Mertins, P., Gunawan, F., Gerhardt, H., Macek, B., Trappmann, B., Schnittler, H.J., Galic, M. and Matis, M.
bioRxiv
: 2024.06.25.600357.
26 June 2024
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction.
Gotthardt, M. and Lehnart, S.E.
Cardiovascular Research 120
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February 2024
Extracellular matrix remodeling in atopic dermatitis harnesses the onset of an asthmatic phenotype and is a potential contributor to the atopic march.
Graff, P., Woerz, D., Wilzopolski, J., Voss, A., Sarrazin, J., Blimkie, T.M., Weiner, J., Kershaw, O., Panwar, P., Hackett, T., Lau, S., Brömme, D., Beule, D., Lee, Y.A., Hancock, R.E.W., Gruber, A.D., Bäumer, W. and Hedtrich, S.
Journal of Investigative Dermatology 144
(5): 1010-1021.
May 2024
Sex-specific structural and functional cardiac remodeling during healthy aging assessed by cardiovascular magnetic resonance.
Grassow, L., Gröschel, J., Saad, H., Krüger, L.D., Kuhnt, J., Müller, M., Hadler, T., Blaszczyk, E. and Schulz-Menger, J.
Clinical Research in Cardiology
11 March 2024
(In Press)
Interaction of sortilin with apolipoprotein E3 enables neurons to use long-chain fatty acids as alternative metabolic fuel.
Greda, A.K., Gomes, J.P., Zurawska-Plaksej, E., Fritsche-Guenther, R., Rudolph, I.M., Telugu, N.S., Cömert, C., Kirwan, J., Kunz, S., Rothe, M., Diecke, S., Bross, P. and Willnow, T.E.
bioRxiv
: 2024.06.10.598173.
10 June 2024
CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.
Greensmith, R., Lape, I.T., Riella, C.V., Schubert, A.J., Metzger, J.J., Dighe, A.S., Tan, X., Hemmer, B., Rau, J., Wendlinger, S., Diederich, N., Schütz, A., Riella, L.V. and Kaminski, M.M.
EMBO Molecular Medicine 16
(10): 2619-2637.
14 October 2024
Kinin B1 receptor modulates glucose homeostasis and physical exercise capacity by altering adrenal catecholamine synthesis and secretion.
Gregnani, M.F., Budu, A., Batista, R.O., Ornellas, F.H., Estrela, G.R., Arruda, A.C., Freitas-Lima, L.C., Kremer, J.L., Favaroni Mendes, L.A., Casarini, D.E., Lotfi, C.F.P., Oyama, L.M., Bader, M. and Araujo, R.C.
Molecular and Cellular Endocrinology 579
: 112085.
1 January 2024
Deep cardiac phenotyping by cardiovascular magnetic resonance reveals subclinical focal and diffuse myocardial injury in patients with psoriasis (PSOR‑COR study).
Gröschel, J., Grassow, L., Blaszczyk, E., Lommel, K., Kokolakis, G., Sabat, R. and Schulz-Menger, J.
Clinical Research in Cardiology
16 May 2024
(In Press)
Trajectories of functional and structural myocardial parameters in post-COVID-19 syndrome - insights from mid-term follow-up by cardiovascular magnetic resonance.
Gröschel, J., Grassow, L., van Dijck, P., Bhoyroo, Y., Blaszczyk, E. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 11
: 1357349.
2 April 2024
Comparison of manual and artificial intelligence based quantification of myocardial strain by feature tracking - a cardiovascular MR study in health and disease.
Gröschel, J., Kuhnt, J., Viezzer, D., Hadler, T., Hormes, S., Barckow, P., Schulz-Menger, J. and Blaszczyk, E.
European Radiology 34
(2): 1003-1015.
February 2024
Integration of CTCF loops, methylome, and transcriptome in differentiating LUHMES as a model for imprinting dynamics of the 15q11-q13 locus in human neurons.
Gutierrez Fugón, O.J., Sharifi, O., Heath, N., Soto, D.C., Gomez, J.A., Yasui, D.H., Mendiola, A.J.P., O'Geen, He., Beitnere, U., Tomkova, M., Haghani, V., Dillon, G., Segal, D.J. and LaSalle, J.M.
Human Molecular Genetics 33
(19): 1711-1725.
1 October 2024
Comparing the extraction performance in mouse plasma of different biphasic methods for polar and nonpolar compounds.
Gutmann, F., Fritsche-Guenther, R., Dias, D.B. and Kirwan, J.A.
Journal of Proteome Research 23
(8): 2961-2969.
2 August 2024
Personality and the use of cancer screenings - results of the German National Cohort.
Hajek, A., Becher, H., Brenner, H., Holleczek, B., Katzke, V., Kaaks, R., Minnerup, H., Karch, A., Baurecht, H., Leitzmann, M., Peters, A., Gastell, S., Ahrens, W., Haug, U., Nimptsch, K., Pischon, T., Michels, K.B., Dorrn, A., Klett-Tammen, C., Castell, S., Willich, S.N., Keil, T., Schipf, S., Meinke-Franze, C., Harth, V., Obi, N. and König, H.H.
Preventive Medicine Reports 41
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May 2024
MR beyond diagnostics at the ESMRMB annual meeting: MR theranostics and intervention.
Hajek, M., Flögel, U., Tavares, A., Nichelli, L., Kennerley, A., Kahn, T., Futterer, J., Firsiori, A., Grüll, H., Saha, N., Couñago, F., Aydogan, D.B., Caligiuri, M.E., Faber, C., Bell, L.C., Figueiredo, P., Vilanova, J.C., Santini, F., Mekle, R. and Waiczies, S.
Magnetic Resonance Materials in Physics, Biology and Medicine 37
(3): 323-328.
July 2024
Reproducibility assessment of rapid strains in cardiac MRI: Insights and recommendations for clinical application.
Halfmann, M.C., Hopman, L.H.G.A., Körperich, H., Blaszczyk, E., Gröschel, J., Schulz-Menger, J., Salatzki, J., André, F., Friedrich, S. and Emrich, T.
European Journal of Radiology 174
: 111386.
May 2024
Using paired-end read orientations to assess technical biases in capture Hi-C.
Hansen, P., Blau, H., Hecht, J., Karlebach, G., Krannich, A., Steinhaus, R., Truss, M. and Robinson, P.N.
NAR Genomics and Bioinformatics 6
(4): lqae156.
December 2024
Tail-cuff versus radiotelemetry to measure blood pressure in mice and rats.
Harrison, D.G., Bader, M., Lerman, L.O., Fink, G., Karumanchi, S.A., Reckelhoff, J.F., Sequeira-Lopez, M.L.S. and Touyz, R.M.
Hypertension 81
(1): 3-5.
January 2024
p53 terminates the regenerative fetal-like state after colitis-associated injury.
Hartl, K., Bayram, Ş., Wetzel, A., Harnack, C., Lin, M., Fischer, A.S., Liu, L., Beccacec, G., Mastrobuoni, G., Geisberger, S., Forbes, M., Monteiro, B.J.E., Macino, M., Flores, R.E., Engelmann, C., Mollenkopf, H.J., Schupp, M., Tacke, F., Sanders, A.D., Kempa, S., Berger, H. and Sigal, M.
Science Advances 10
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25 October 2024
A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI).
Hartmann, C.R., Khan, R., Schöning, J., Richter, M., Willers, M., Pirr, S., Heckmann, J., Dirks, J., Morbach, H., Konrad, M., Fries, E., Winkler, M., Büchel, J., Seidenspinner, S., Fischer, J., Vollmuth, C., Meinhardt, M., Marissen, J., Schmolke, M., Haid, S., Pietschmann, T., Backes, S., Dölken, L., Löber, U., Keil, T., Heuschmann, P.U., Wöckel, A., Sagar, Dr., Ulas, T., Forslund-Startceva, S.K., Härtel, C. and Viemann, D.
Frontiers in Immunology 15
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17 September 2024
The effects of hypoxia on the immune-metabolic interplay in liver cancer.
He, Y., Xu, H., Liu, Y., Kempa, S., Vechiatto, C., Schmidt, R., Yilmaz, E.Y., Heidemann, L., Schnorr, J., Metzkow, S., Schellenberger, E., Häckel, A., Patzak, A., Müller, D.N. and Savic, L.J.
Biomolecules 14
(8): 1024.
17 August 2024
Mutations in CLCN6 as a novel genetic cause of neuronal ceroid lipofuscinosis in patients and a murine model.
He, H., Cao, X., He, F., Zhang, W., Wang, X., Peng, P., Xie, C., Yin, F., Li, D., Li, J., Wang, M., Klüssendorf, M., Jentsch, T.J., Stauber, T. and Peng, J.
Annals of Neurology 96
(3): 608-624.
September 2024
Perioperative levels of IL8 and IL18, but not IL6, are associated with nucleus basalis magnocellularis atrophy three months after surgery.
Heinrich, M., Spies, C., Borchers, F., Feinkohl, I., Pischon, T., Slooter, A.J.C., von Haefen, C., Zacharias, N., Winterer, G. and Lammers-Lietz, F.
Journal of Neuroimmune Pharmacology 19
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14 March 2024
Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response.
Hendrickson, T., Giese, A., Fiedler, M., Perez, W., Reyes-Sanchez, E., Reyes-Lozano, M., Wang, S., Venegas-Zamora, L., Provasek, V., El-Essawi, A., Breitenbach, I., Fakuade, F.E., Kutschka, I., Schiattarella, G.G., Voigt, N., Valderrabano, M. and Altamirano, F.
bioRxiv
: 2024.07.08.602618.
12 July 2024
Changes in physical activity and sedentary behavior during the first COVID-19 pandemic- restrictions in Germany: a nationwide survey : Running head: physical activity during the COVID-19 restrictions.
Herbolsheimer, F., Peters, A., Wagner, S., Willich, S.N., Krist, L., Pischon, T., Nimptsch, K., Gastell, S., Brandes, M., Brandes, B., Schikowski, T., Schmidt, B., Michels, K.B., Mikolajczyk, R., Harth, V., Obi, N., Castell, S., Heise, J.K., Lieb, W., Franzpötter, K., Karch, A., Teismann, H., Völzke, H., Meinke-Franze, C., Leitzmann, M., Stein, M.J., Brenner, H., Holleczek, B., Weber, A., Bohn, B., Kluttig, A. and Steindorf, K.
BMC Public Health 24
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12 February 2024
Cell-mechanical parameter estimation from 1D cell trajectories using simulation-based inference.
Heyn, J., Atienza Juanatey, M., Falcke, M. and Raedler, J.
bioRxiv
: 2024.09.06.611766.
8 September 2024
Mesenchymal cell migration on one-dimensional micropatterns.
Heyn, J.C.J., Rädler, J.O. and Falcke, M.
Frontiers in Cell and Developmental Biology 12
: 1352279.
16 April 2024
Nourishing the mind: fasting for brain health.
Hofer, S.J. and Madeo, F.
Cell Metabolism 36
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6 August 2024
Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Hofman, D.A., Ruiz-Orera, J., Yannuzzi, I., Murugesan, R., Brown, A., Clauser, K.R., Condurat, A.L., van Dinter, J.T., Engels, S.A.G., Goodale, A., van der Lugt, J., Abid, T., Wang, L., Zhou, K.N., Vogelzang, J., Ligon, K.L., Phoenix, T.N., Roth, J.A., Root, D.E, Hubner, N., Golub, T.R., Bandopadhayay, P., van Heesch, S. and Prensner, J.R.
Molecular Cell 84
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18 January 2024
Gut dysbiosis contributes to TMAO accumulation in CKD.
Holle, J., McParland, V., Anandakumar, H., Gerritzmann, F., Behrens, F., Schumacher, F., Thumfart, J., Eckardt, K.U., Kleuser, B., Bartolomaeus, H. and Wilck, N.
Nephrology Dialysis Transplantation 39
(11): 1923-1926.
November 2024
Gut microbiome alterations precede graft rejection in kidney transplantation patients.
Holle, J., Reitmeir, R., Behrens, F., Singh, D., Schindler, D., Potapenko, O., McParland, V., Anandakumar, H., Kanzelmeyer, N., Sommerer, C., Hartleif, S., Andassy, J., Heemann, U., Neuenhahn, M., Forslund-Startceva, S.K., Gerhard, M., Oh, J., Wilck, N., Löber, U. and Bartolomaeus, H.
medRxiv
: 2024.05.21.24307660.
21 May 2024
Childhood and adolescence factors and multiple sclerosis: results from the German National Cohort (NAKO).
Holz, A., Obi, N., Ahrens, W., Berger, K., Bohn, B., Brenner, H., Fischer, B., Fricke, J., Führer, A., Gastell, S., Greiser, K.H., Harth, V., Heise, J.K., Holleczek, B., Keil, T., Klett-Tammen, C.J., Leitzmann, M., Lieb, W., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Nimptsch, K., Peters, A., Pischon, T., Riedel, O., Schikowski, T., Schipf, S., Schmidt, B., Schulze, M.B., Stang, A., Hellwig, K., Riemann-Lorenz, K., Heesen, C. and Becher, H.
BMC Neurology 24
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13 April 2024
Quantification of myocardial effective transverse relaxation time with magnetic resonance at 7.0 Tesla for a better understanding of myocardial (patho)physiology.
Huelnhagen, T., Serradas-Duarte, T., Hezel, F., Paul, K. and Niendorf, T.
In:
Quantification of Biophysical Parameters in Medical Imaging.
Springer, Cham, Switzerland, 381-406.
ISBN 978-3-031-61846-8
5 November 2024
3D whole heart k-space-based super-resolution cardiac T1 mapping using rotated stacks.
Hufnagel, S., Schuenke, P., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Physics in Medicine and Biology 69
(8): 085027.
9 April 2024
Microglia from patients with multiple sclerosis display a cell-autonomous immune activation state.
Hyvärinen, T., Lotila, J., Giudice, L., Tujula, I., Nylund, M., Ohtonen, S., Scoyni, F., Jäntti, H., Pihlava, S., Skottman, H., Narkilahti, S., Airas, L., Malm, T. and Hagman, S.
bioRxiv
: 2024.12.10.627477.
11 December 2024
Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies.
Hüttemeister, J., Rudolph, F., Radke, M.H., Fink, C., Friedrich, D., Preibisch, S., Falcke, M., Wagner, E., Lehnart, S.E. and Gotthardt, M.
eLife 13
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17 December 2024
Extensive folding variability between homologous chromosomes in mammalian cells.
Irastorza-Azcarate, I., Kukalev, A., Kempfer, R., Thieme, C.J., Mastrobuoni, G., Markowski, J., Loof, G., Sparks, T.M., Brookes, E., Natarajan, K.N., Sauer, S., Fisher, A.G., Nicodemi, M., Ren, B., Schwarz, R.F., Kempa, S. and Pombo, A.
bioRxiv
: 2024.05.08.591087.
10 May 2024
Non-viral targeted insertion of large payloads into T cells.
Izsvak, Z.
Nature Biomedical Engineering 8
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December 2024
Aberrant microbiomes are associated with increased antibiotic resistance gene load in hybrid mice.
Jarquín-Díaz, V.H., Ferreira, S.C.M., Balard, A., Ďureje, L., Macholán, M., Piálek, J., Bengtsson-Palme, J., Kramer-Schadt, S., Forslund-Startceva, S.K. and Heitlinger, E.
ISME Communications 4
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15 April 2024
Quantifying model uncertainty for semantic segmentation of Fluorine-19 MRI using stochastic gradient MCMC.
Javanbakhat, M., Starke, L., Waiczies, S. and Lippert, C.
Computer Vision and Image Understanding 241
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April 2024
Examining the healthy human microbiome concept.
Joos, R., Boucher, K., Lavelle, A., Arumugam, M., Blaser, M.J., Claesson, M.J., Clarke, G., Cotter, P.D., De Sordi, L., Dominguez-Bello, M.G., Dutilh, B.E., Ehrlich, S.D., Ghosh, T.S., Hill, C., Junot, C., Lahti, L., Lawley, T.D., Licht, T.R., Maguin, E., Makhalanyane, T.P., Marchesi, J.R., Matthijnssens, J., Raes, J., Ravel, J., Salonen, A., Scanlan, P.D., Shkoporov, A., Stanton, C., Thiele, I., Tolstoy, I., Walter, J., Yang, B., Yutin, N., Zhernakova, A., Zwart, H., Doré, J. and Ross, R.P.
Nature Reviews Microbiology
23 October 2024
(In Press)
Use of mesna prophylaxis in patients with cyclophosphamide-treated ANCA-associated vasculitis: cross-sectional survey of practitioners.
Joos, L., Gonzalez Chiappe, S., Neumann, T. and Mahr, A.
Rheumatology International 44
(12): 3099-3106.
December 2024
Dentition patterns and molecular diversity of Mastophorus muris (Gmelin, 1790) (Nematoda: Spiruroidea) support a host-associated subdivision.
Jost, J., Hirzmann, J., Ďureje, Ľ., Maaz, D., Martin, P., Stach, T., Heitlinger, E. and Jarquín-Díaz, V.H.
Parasitology Research 123
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June 2024
A gender perspective on diet, microbiome, and sex hormone interplay in cardiovascular disease.
Jovanovic, N., Zach, V., Crocini, C., Bahr, L.S., Forslund-Startceva, S.K. and Franz, K.
Acta Physiologica 240
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November 2024
An altered plasma lipidome-phenome network characterizes heart failure with preserved ejection fraction.
Jovanovic, N., Foryst-Ludwig, A., Klose, C., da Conceicao, C.R., Alasfar, L., Birkner, T., Forslund, S.K., Kintscher, U. and Edelmann, F.
ESC Heart Failure 11
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June 2024
Deep learning-based body composition analysis from whole-body magnetic resonance imaging to predict all-cause mortality in a large western population.
Jung, M., Raghu, V.K., Reisert, M., Rieder, H., Rospleszcz, S., Pischon, T., Niendorf, T., Kauczor, H.U., Völzke, H., Bülow, R., Russe, M.F., Schlett, C.L., Lu, M.T., Bamberg, F. and Weiss, J.
EBioMedicine 110
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December 2024
SetQuence & SetOmic: deep set transformers for whole genome and exome tumour analysis.
Jurenaite, N., León-Periñán, D., Donath, V., Torge, S. and Jäkel, R.
Biosystems 235
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January 2024
Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment.
Juul-Madsen, K., Parbo, P., Ismail, R., Ovesen, P.L., Schmidt, V., Madsen, L.S., Thyrsted, J., Gierl, S., Breum, M., Larsen, A., Andersen, M.N., Romero-Ramos, M., Holm, C.K., Andersen, G.R., Zhao, H., Schuck, P., Nygaard, J.V., Sutherland, D.S., Eskildsen, S.F., Willnow, T.E., Brooks, D.J. and Vorup-Jensen, T.
Nature Communications 15
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9 February 2024
Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment.
Kaiser, R., Gold, C., Joppich, M., Loew, Q., Akhalkatsi, A., Mueller, T.T., Offensperger, F., Droste Zu Senden, A., Popp, O., di Fina, L., Knottenberg, V., Martinez-Navarro, A., Eivers, L., Anjum, A., Escaig, R., Bruns, N., Briem, E., Dewender, R., Muraly, A., Akgöl, S., Ferraro, B., Hoeflinger, J.K.L., Polewka, V., Khaled, N.B., Allgeier, J., Tiedt, S., Dichgans, M., Engelmann, B., Enard, W., Mertins, P., Hubner, N., Weckbach, L., Zimmer, R., Massberg, S., Stark, K., Nicolai, L. and Pekayvaz, K.
Science Advances 10
(12): eadl1710.
22 March 2024
Tolerance induction through early feeding to prevent food allergy in infants and children with sensitization against food allergens (TIFFANI): rationale, study design, and methods of a randomized controlled trial.
Kalb, B., Meixner, L., Heller, S., Dölle-Bierke, S., Roll, S., Tissen-Diabaté, T., Lau, S., Forslund, S., Marenholz, I., Lee, Y.A., Thiel, A., Babina, M., Scheffel, J., Worm, M. and Beyer, K.
Trials 25
: 272.
19 April 2024
SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells.
Kalnytska, O., Qvist, P., Kunz, S., Conrad, T., Willnow, T.E. and Schmidt, V.
iScience 27
(1): 108725.
19 January 2024
SorLA restricts TNFα release from microglia to shape a glioma-supportive brain microenvironment.
Kaminska, P., Ovesen, P.L., Jakiel, M., Obrebski, T., Schmidt, V., Draminski, M., Bilska, A.G., Bieniek, M., Anink, J., Paterczyk, B., Jensen, A.M.G., Piatek, S., Andersen, O.M., Aronica, E., Willnow, T.E., Kaminska, B., Dabrowski, M.J. and Malik, A.R.
EMBO Reports 25
(5): 2278-2305.
May 2024
Refined enterotyping reveals dysbiosis in global fecal metagenomes.
Keller, M.I., Nishijima, S., Podlesny, D., Kim, C.Y., Robbani, S.M., Schudoma, C., Fullam, A., Richter, J., Letunic, I., Akanni, W., Orakov, A., Schmidt, T.S., Marotta, F., Trebicka, J., Kuhn, M., Van Rossum, T. and Bork, P.
bioRxiv
: 2024.08.13.607711v2.
14 August 2024
MRT-basierte automatische Nierensegmentierung und daraus abgeleitete Marker: Eine Auswertung der bevölkerungsweiten NAKO Gesundheitsstudie.
Kellner, E., Sekula, P., Lipovsek, J., Russe, M., Horbach, H., Schlett, C.L., Nauck, M., Völzke, H., Kroencke, T., Bette, S., Kauczor, H.U., Keil, T., Pischon, T., Heid, I.M., Peters, A., Niendorf, T., Lieb, W., Bamberg, F., Büchert, M, Reichardt, W., Reisert, M. and Köttgen, A.
Deutsches Arzteblatt 121
: 284-290.
3 May 2024
Imaging markers derived from MRI-based automated kidney segmentation - an analysis of data from the German National Cohort (NAKO Gesundheitsstudie).
Kellner, E., Sekula, P., Lipovsek, J., Russe, M., Horbach, H., Schlett, C.L., Nauck, M., Völzke, H., Kröncke, T., Bette, S., Kauczor, H.U., Keil, T., Pischon, T., Heid, I.M., Peters, A., Niendorf, T., Lieb, W., Bamberg, F., Büchert, M., Reichardt, W., Reisert, M. and Köttgen, A.
Deutsches Arzteblatt International 121
(9): 284-290.
3 May 2024
Using routinely collected clinical data for circadian medicine: A review of opportunities and challenges.
Kervezee, L., Dashti, H.S., Pilz, L.K., Skarke, C. and Ruben, M.D.
PLoS Digital Health 3
(5): e0000511.
23 May 2024
Dysnatriämien - Konzepte und klinische Aufarbeitung [Dysnatremias - concepts and clinical work-up].
Kettritz, R.
Deutsche Medizinische Wochenschrift 149
(3): 86-92.
February 2024
The association of a healthy lifestyle index and imaging-based body fat distribution with glycemic status and Type 2 diabetes in the Multi Ethnic Cohort: a cross-sectional analysis.
Klapp, R., Nimptsch, K., Pischon, T., Wilkens, L.R., Lim, U., Guillermo, C., Setiawan, V.W., Shepherd, J.A, Le Marchand, L. and Maskarinec, G.
European Journal of Clinical Nutrition 78
(3): 236-242.
March 2024
Dynamic parametric MRI and deep learning: unveiling renal pathophysiology through accurate kidney size quantification.
Klein, T., Gladytz, T., Millward, J.M., Cantow, K., Hummel, L., Seeliger, E., Waiczies, S., Lippert, C. and Niendorf, T.
NMR in Biomedicine 37
(4): e5075.
April 2024
β(2)-integrins control HIF1α activation in human neutrophils.
Kling, L., Eulenberg-Gustavus, C., Jerke, U., Rousselle, A., Eckardt, K.U., Schreiber, A. and Kettritz, R.
Frontiers in Immunology 15
: 1406967.
14 October 2024
Childhood trauma and somatic and mental illness in adulthood.
Klinger-König, J., Erhardt, A., Streit, F., Völker, M.P., Schulze, M.B, Keil, T., Fricke, J., Castell, S., Klett-Tammen, C.J., Pischon, T., Karch, A., Teismann, H., Michels, K.B., Greiser, K.H., Becher, H., Karrasch, S., Ahrens, W., Meinke-Franze, C., Schipf, S., Mikolajczyk, R., Führer, A., Brandes, B., Schmidt, B., Emmel, C., Leitzmann, M., Konzok, J., Peters, A., Obi, N., Brenner, H., Holleczek, B., Moreno Velásquez, I., Deckert, J., Baune, B.T., Rietschel, M., Berger, K. and Grabe, H.J.
Deutsches Arzteblatt International 121
(1): 1-8.
12 January 2024
Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling.
Kocere, A., Chiavacci, E., Soneson, C., Wells, H.H., Mendez-Acevedo, K.M., MacGowan, J.S., Jacobson, S.T., Hiltabidle, M.S., Raghunath, A., Shavit, J.A., Panákova, D., Williams, M.L.K., Robinson, M.D., Mosimann, C. and Burger, A.
bioRxiv
: 2023.04.12.536513v4.
1 February 2024
International consensus on fasting terminology.
Koppold, D.A., Breinlinger, C., Hanslian, E., Kessler, C., Cramer, H., Khokhar, A.R., Peterson, C.M., Tinsley, G., Vernieri, C., Bloomer, R.J., Boschmann, M., Bragazzi, N.L., Brandhorst, S., Gabel, K., Goldhamer, A.C., Grajower, M.M., Harvie, M., Heilbronn, L., Horne, B.D., Karras, S.N., Langhorst, J., Lischka, E., Madeo, F., Mitchell, S.J., Papagiannopoulos-Vatopaidinos, I.E., Papagiannopoulou, M., Pijl, H., Ravussin, E., Ritzmann-Widderich, M., Varady, K., Adamidou, L., Chihaoui, M., de Cabo, R., Hassanein, M., Lessan, N., Longo, V., Manoogian, E.N.C., Mattson, M.P., Muhlestein, J.B., Panda, S., Papadopoulou, S.K., Rodopaios, N.E., Stange, R. and Michalsen, A.
Cell Metabolism 36
(8): 1779-1794.
6 August 2024
Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids.
Kranrod, J., Konkel, A., Valencia, R., Darwesh, A., Fischer, R., Schunck, W.H. and Seubert, J.M.
Journal of Biological Chemistry 300
(6): 107372.
June 2024
UV light exposure versus vitamin D supplementation: a comparison of health benefits and vitamin D metabolism in a pig model.
Kühn, J., Brandsch, C., Bailer, A.C., Kiourtzidis, M., Hirche, F., Chen, C.Y., Markó, L., Bartolomaeus, T.U.P., Löber, U., Michel, S., Wensch-Dorendorf, M., Forslund-Startceva, S.K. and Stangl, G.I.
Journal of Nutritional Biochemistry 134
: 109746.
December 2024
Protein intake and cancer: an umbrella review of systematic reviews for the evidence‑based guideline of the German Nutrition Society.
Kühn, T., Kalotai, N., Amini, A.M., Haardt, J., Lehmann, A., Schmidt, A., Buyken, A.E., Egert, S., Ellinger, S., Kroke, A., Lorkowski, S., Louis, S., Schulze, M.B., Schwingshackl, L., Siener, R., Stangl, G.I., Watzl, B., Zittermann, A. and Nimptsch, K.
European Journal of Nutrition 63
(5): 1471-1486.
August 2024
Management of immune thrombotic thrombocytopenic purpura without therapeutic plasma exchange.
Kühne, L., Knöbl, P., Eller, K., Thaler, J., Sperr, W.R., Gleixner, K., Osterholt, T., Kaufeld, J., Menne, J., Buxhofer-Ausch, V., Mühlfeld, A., Seelow, E., Schreiber, A., Todorova, P., Cukoski, S., Jabs, W.J., Özcan, F., Gäckler, A., Schönfelder, K., Seibert, F.S., Westhoff, T., Schwenger, V., Eichenauer, D.A., Völker, L.A. and Brinkkoetter, P.T.
Blood 144
(14): 1486-1495.
3 October 2024
Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response.
Lafranchi, L., Spinner, A., Hornisch, M., Schlesinger, D., Luzon, C.N., Brinkenstråhle, L., Shao, R., Piazza, I. and Elsässer, S.J.
bioRxiv
: 2024.12.08.627409.
9 December 2024
Long-read sequencing reveals extensive gut phageome structural variations driven by genetic exchange with bacterial hosts.
Lai, S., Wang, H., Bork, P., Chen, W.H. and Zhao, X.M.
Science Advances 10
(33): eadn3316.
16 August 2024
An exploratory research report on brain mineralization in postoperative delirium and cognitive decline.
Lammers-Lietz, F., Borchers, F., Feinkohl, I., Hetzer, S., Kanar, C., Konietschke, F., Lachmann, G., Chien, C., Spies, C., Winterer, G., Zaborszky, L., Zacharias, N. and Paul, F.
European Journal of Neuroscience 59
(10): 2646-2664.
May 2024
Estimates of protection levels against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season: the IMMUNEBRIDGE project.
Lange, B., Jaeger, V.K., Harries, M., Rücker, V., Streeck, H., Blaschke, S., Petersmann, A., Toepfner, N., Nauck, M., Hassenstein, M.J., Dreier, M., von Holt, I., Budde, A., Bartz, A., Ortmann, J., Kurosinski, M.A., Berner, R., Borsche, M., Brandhorst, G., Brinkmann, M., Budde, K., Deckena, M., Engels, G., Fenzlaff, M., Härtel, C., Hovardovska, O., Katalinic, A., Kehl, K., Kohls, M., Krüger, S., Lieb, W., Meyer-Schlinkmann, K.M., Pischon, T., Rosenkranz, D., Rübsamen, N., Rupp, J., Schäfer, C., Schattschneider, M., Schlegtendal, A., Schlinkert, S., Schmidbauer, L., Schulze-Wundling, K., Störk, S., Tiemann, C., Völzke, H., Winter, T., Klein, C., Liese, J., Brinkmann, F., Ottensmeyer, P.F., Reese, J.P., Heuschmann, P. and Karch, A.
Infection 52
(1): 139-153.
February 2024
Soluble ACE2 correlates with severe COVID-19 and can impair antibody responses.
Lebedin, M., Ratswohl, C., Garg, A., Schips, M., Vazquez Garcia, C., Spatt, L., Thibeault, C., Obermayer, B., Weiner, J., Moreno Velásquez, I., Gerhard, C., Stubbemann, P., Hanitsch, L.G., Pischon, T., Witzenrath, M., Sander, L.E., Kurth, F., Meyer-Hermann, M. and de la Rosa, K.
iScience 27
(3): 109330.
15 March 2024
Novel tryptophan hydroxylase inhibitor TPT-001 reverses PAH, vascular remodeling, and proliferative-proinflammatory gene expression.
Legchenko, E., Chouvarine, P., Qadri, F., Specker, E., Nazaré, M., Wesolowski, R., Matthes, S., Bader, M. and Hansmann, G.
JACC: Basic to Translational Science 9
(7): 890-902.
July 2024
Blocking glycosphingolipid production alters autophagy in osteoclasts and improves myeloma bone disease.
Leng, H., Simon, A.K. and Horwood, N.J.
Autophagy 20
(4): 930-932.
April 2024
Reliable off-resonance correction in high-field cardiac MRI using autonomous cardiac B0 segmentation with dual-modality deep neural networks.
Li, X., Huang, Y., Malagi, A., Yang, C.C., Yoosefian, G., Huang, L.T., Tang, E., Gao, C., Han, Fei, Bi, X., Ku, M.C., Yang, H.J. and Han, H.
Bioengineering 11
(3): 210.
23 February 2024
Converting PROMIS®-29 v2.0 profile data to SF-36 physical and mental component summary scores in patients with cardiovascular disorders.
Liegl, G., Fischer, F.H., Martin, C.N., Rönnefarth, M., Blumrich, A., Ahmadi, M., Boldt, L.H., Eckardt, K.U., Endres, M., Edelmann, F., Gerhardt, H., Grittner, U., Haghikia, A., Hübner, N., Landmesser, U., Leistner, D., Mai, K., Kollmus-Heege, J., Müller, D.N., Nolte, C.H., Piper, S.K., Schmidt-Ott, K.M., Pischon, T., Rattan, S., Rohrpasser-Napierkowski, Ira, Schönrath, K., Schulz-Menger, J., Schweizerhof, O., Spranger, J., Weber, J.E., Witzenrath, M., Schmidt, S. and Rose, M.
Health and Quality of Life Outcomes 22
(1): 64.
15 August 2024
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Lisowski, P., Lickfett, S., Rybak-Wolf, A., Menacho, C., Le, S., Pentimalli, T.M., Notopoulou, S., Dykstra, W., Oehler, D., López-Calcerrada, S., Mlody, B., Otto, M., Wu, H., Richter, Y., Roth, P., Anand, R., Kulka, L.A.M., Meierhofer, D., Glazar, P., Legnini, I., Telugu, N.S., Hahn, T., Neuendorf, N., Miller, D.C., Böddrich, A., Polzin, A., Mayatepek, E., Diecke, S., Olzscha, H., Kirstein, J., Ugalde, C., Petrakis, S., Cambridge, S., Rajewsky, N., Kühn, R., Wanker, E.E., Priller, J., Metzger, J.J. and Prigione, A.
Nature Communications 15
(1): 7027.
22 August 2024
Quantification of multi-compartment flow with spectral diffusion MRI.
Liu, M.M., Dyke, J., Gladytz, T., Jasse, J., Bolger, I., Calle, S., Pavaluri, S., Crews, T., Seshan, S., Salvatore, S., Stillman, I., Muthukuma, T., Taouli, B., Farouk, S., Lewis, S. and Bane, O.
arXiv
: 2408.06427.
12 August 2024
The role of glycocalyx diversity and thickness for nanoparticle internalization in M1-/M2-like macrophages.
Liu, Y., He, Y., Xu, H., Remmo, A., Wiekhorst, F., Heymann, F., Liu, H., Schellenberger, E., Häckel, A., Hauptmann, R., Taupitz, M., Shen, Y., Yilmaz, E.Y., Müller, D.N., Heidemann, L., Schmidt, R. and Savic, L.J.
Nano Letters 24
(49): 15607-15614.
11 December 2024
CD19-targeting CAR T cells protect from ANCA-induced acute kidney injury.
Lodka, D., Zschummel, M., Bunse, M., Rousselle, A., Sonnemann, J., Kettritz, R., Höpken, U.E. and Schreiber, A.
Annals of the Rheumatic Diseases 83
(4): 499-507.
12 March 2024
Molecular characterization of nodose ganglia development reveals a novel population of Phox2b+ glial progenitors in mice.
Lowenstein, E.D., Misios, A., Buchert, S. and Ruffault, P.L.
Journal of Neuroscience 44
(28): e1441232024.
10 July 2024
Personal genetic-hypertension odyssey from phenotypes to genotypes and targets.
Luft, F.C.
Hypertension 81
(12): 2395-2406.
December 2024
Calcineurin inhibition, cardiovascular consequences, vascular resistance, and potential responses.
Luft, F.C.
Acta Physiologica 240
(3): e14084.
March 2024
Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.
Lyu, Y.X., Fu, Q., Wilczok, D., Ying, K., King, A., Antebi, A., Vojta, A., Stolzing, A., Moskalev, A., Georgievskaya, A., Maier, A.B., Olsen, A., Groth, A., Simon, A.K., Brunet, A., Jamil, A., Kulaga, A., Bhatti, A., Yaden, B., Pedersen, B.K., Schumacher, B., Djordjevic, B., Kennedy, B., Chen, C., Huang, C.Y., Correll, C.U., Murphy, C.T., Ewald, C.Y., Chen, D., Valenzano, D.R., Sołdacki, D., Erritzoe, D., Meyer, D., Sinclair, D.A., Chini, E.N., Teeling, E.C., Morgen, E., Verdin, E., Vernet, E., Pinilla, E., Fang, E.F., Bischof, E., Mercken, E.M., Finger, F., Kuipers, F., Pun, F.W., Gyülveszi, G., Civiletto, G., Zmudze, G., Blander, G., Pincus, H.A., McClure, J., Kirkland, J.L., Peyer, J., Justice, J.N., Vijg, J., Gruhn, J.R., McLaughlin, J., Mannick, J., Passos, J., Baur, J.A., Betts-LaCroix, J., Sedivy, J.M., Speakman, J.R., Shlain, J., von Maltzahn, J., Andreasson, K.I., Moody, K., Palikaras, K., Fortney, K., Niedernhofer, L.J., Rasmussen, L.J., Veenhoff, L.M., Melton, L., Ferrucci, L., Quarta, M., Koval, M., Marinova, M., Hamalainen, M., Unfried, M., Ringel, M.S., Filipovic, M., Topors, M., Mitin, N., Roy, N., Pintar, N., Barzilai, N., Binetti, P., Singh, P., Kohlhaas, P., Robbins, P.D., Rubin, P., Fedichev, P.O., Kamya, P., Muñoz-Canoves, P., de Cabo, R., Faragher, R.G.A., Konrad, R., Ripa, R., Mansukhani, R., Büttner, S., Wickström, S.A., Brunemeier, S., Jakimov, S., Luo, S., Rosenzweig-Lipson, S., Tsai, S.Y., Dimmeler, S., Rando, T.A., Peterson, T.R., Woods, T., Wyss-Coray, T., Finkel, T., Strauss, T., Gladyshev, V.N., Longo, V.D., Dwaraka, V.B., Gorbunova, V., Acosta-Rodríguez, V.A., Sorrentino, V., Sebastiano, V., Li, W., Suh, Y., Zhavoronkov, A., Scheibye-Knudsen, M. and Bakula, D.
Aging 16
(20): 12955-12976.
31 October 2024
Impact of training data composition on the generalizability of convolutional neural network aortic cross-section segmentation in four-dimensional magnetic resonance flow imaging.
Manini, C., Hüllebrand, M., Walczak, L., Nordmeyer, S., Jarmatz, L., Kuehne, T., Stern, H., Meierhofer, C., Harloff, A., Erley, J., Kelle, S., Bannas, P., Trauzeddel, R.F., Schulz-Menger, J. and Hennemuth, A.
Journal of Cardiovascular Magnetic Resonance 26
(2): 101081.
8 August 2024
A simulation-based phantom model for generating synthetic mitral valve image data-application to MRI acquisition planning.
Manini, C., Nemchyna, O., Akansel, S., Walczak, L., Tautz, L., Kolbitsch, C., Falk, V., Sündermann, S., Kühne, T., Schulz-Menger, J. and Hennemuth, A.
International Journal of Computer Assisted Radiology and Surgery 19
(3): 553-569.
March 2024
Water conservation overrides osmotic diuresis during SGLT2 inhibition in patients with heart failure.
Marton, A., Saffari, S.E., Rauh, M., Sun, R.N., Nagel, A.M., Linz, P., Lim, T.T., Takase-Minegishi, K., Pajarillaga, A., Saw, S., Morisawa, N., Yam, W.K., Minegishi, S., Totman, J.J., Teo, S., Teo, L.L.Y., Ng, C.T., Kitada, K., Wild, J., Kovalik, J.P., Luft, F.C., Greasley, P.J., Chin, C.W.L., Sim, D.K.L. and Titze, J.
Journal of the American College of Cardiology 83
(15): 1386-1398.
16 April 2024
Hypertrophic obstructive cardiomyopathy-left ventricular outflow tract shapes and their hemodynamic influences applying CMR.
Mayr, T., Riazy, L., Trauzeddel, R.F., Bassenge, J.P., Wiesemann, S., Blaszczyk, E., Prothmann, M., Hadler, T., Schmitter, S. and Schulz-Menger, J.
International Journal of Cardiovascular Imaging 40
(11): 2371-2381.
November 2024
Women in Autophagy: an initiative to promote gender parity in science.
McCabe, M., Boya, P., Chen, R.H., Chu, C.T., Colombo, M.I., Delgui, L., Eskelinen, E.L., Hamasaki, M., Hansen, M., He, C., Jäättelä, M., Kimchi, A., Kraft, C., Kundu, M., Melendez, A., Pattingre, S., Proikas-Cezanne, T., Sebti, S., Simon, A.K., Simonsen, A., Tooze, S.A., Vaccaro, M.I., Wang, X., White, E., Zhao, Y. and Cuervo, A.M.
Nature Cell Biology 26
(12): 2009-2012.
December 2024
Kommentar zu den Leitlinien 2023 der ESC zum Management von Kardiomyopathien.
Meder, B., Eckardt, L., Falk, V., Klaassen, S., Klingenheben, T., Knebel, F., Schulze-Bahr, E. and Schulz-Menger, J.
Kardiologie
9 April 2024
External mechanical stability regulates hematoma vascularization in bone healing rather than endothelial YAP/TAZ mechanotransduction.
Mehl, J., Farahani, S.K., Brauer, E., Klaus-Bergmann, A., Thiele, T., Ellinghaus, A., Bartels-Klein, E., Koch, K., Schmidt-Bleek, K., Petersen, A., Gerhardt, H., Vogel, V. and Duda, G.N.
Advanced Science 11
(13): e2307050.
3 April 2024
Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease.
Menacho, C., Okawa, S., Alvarez-Merz, I., Wittich, A., Muñoz-Oreja, M., Lisowski, P., Pentimalli, T.M., Rybak-Wolf, A., Inak, G., Zakin, S., Thevandavakkam, M., Petersilie, L., Zaliani, A., Mlody, B., Seibt, A., Donnelly, J., Woleben, K., Fernandez-Checa, J., Herebian, D., Mayatepek, E., Rajewsky, N., Spinazzola, A., Schuelke, M., Perlstein, E., Rossi, A., Distelmaier, F., Holt, I.J., Pless, O., Rose, C., Del Sol, A. and Prigione, A.
bioRxiv
: 2024.07.08.602501.
12 July 2024
Imlifidase – ein innovativer Therapieansatz in der Nephrologie [Imlifidase - an innovative treatment approach in nephrology].
Mestekemper, A.N. and Schreiber, A.
Nephrologie 19
: 248-251.
July 2024
Likelihood of post-COVID condition in people with hybrid immunity; data from the German National Cohort (NAKO).
Mikolajczyk, R., Diexer, S., Klee, B., Pfrommer, L., Purschke, O., Fricke, J., Ahnert, P., Gabrysch, S., Gottschick, C., Bohn, B., Brenner, H., Buck, C., Castell, S., Gastell, S., Greiser, K.H., Harth, V., Heise, J.K., Holleczek, B., Kaaks, R., Keil, T., Krist, L., Leitzmann, M., Lieb, W., Meinke-Franze, Cl., Michels, K.B., Moreno Velásquez, I., Obi, N., Panreck, L., Peters, A., Pischon, T., Schikowski, T., Schmidt, B., Standl, M., Stang, A., Völzke, H., Weber, A., Zeeb, H. and Karch, A.
Journal of Infection 89
(2): 106206.
August 2024
Sodium as an important regulator of immunometabolism.
Miyauchi, H., Geisberger, S., Luft, F.C., Wilck, N., Stegbauer, J., Wiig, H., Dechend, R., Jantsch, J., Kleinewietfeld, M., Kempa, S. and Mueller, D.N.
Hypertension 81
(3): 426-435.
March 2024
Glycolysis–Wnt signaling axis tunes developmental timing of embryo segmentation.
Miyazawa, H., Rada, J., Sanchez, P.G.L., Esposito, E., Bunina, D., Girardot, C., Zaugg, J. and Aulehla, A.
bioRxiv
: 2024.01.22.576629v2.
23 January 2024
The association of pre-operative biomarkers of endothelial dysfunction with the risk of post-operative neurocognitive disorders: results from the BioCog study.
Moazzen, S., Janke, J., Slooter, A.J.C., Winterer, G., Spies, C., Pischon, T. and Feinkohl, I.
BMC Anesthesiology 24
(1): 358.
8 October 2024
Disruption of basal CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.
Mobach, S, Bergkamp, N.D., Ma, Z, Haselager, M.V., Anbuhl, S.M., Jurriens, D, van den Bor, J., Wang, Z., Crudden, C., Roos, J.L., Perez Almeria, C.V., Boergonje, R.A., Lohse, M.J., Bosma, R., Eldering, E., Siderius, M., Wu, W., Spaargaren, M., Tonino, S.H., Kater, A.P., Smit, M.J. and Heukers, R.
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SPINEPS-automatic whole spine segmentation of T2-weighted MR images using a two-phase approach to multi-class semantic and instance segmentation.
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European Radiology
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Inter-site comparability of 4D flow cardiovascular magnetic resonance measurements in healthy traveling volunteers -- a multi-site and multi-magnetic field strength study.
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Fluorescent tools for the imaging of dopamine D2-like receptors.
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ACE2 knockout mice are resistant to high-fat diet-induced obesity in an age-dependent manner.
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Simulating rigid head motion artifacts on brain magnitude MRI data-Outcome on image quality and segmentation of the cerebral cortex.
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Glia
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Human genetics of defects of situs.
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Human genetics of ventricular septal defect.
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18 June 2024
In preprints: keeping endothelial cell specification and vascular development in check.
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Pre-diagnostic circulating resistin concentrations and mortality among individuals with colorectal cancer: results from the European Prospective Investigation into Cancer and Nutrition study.
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Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling.
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Identifying chromosome movement patterns during meiosis using ChroMo.
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Hif-2α programs oxygen chemosensitivity in chromaffin cells.
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Scalable image-based visualization and alignment of spatial transcriptomics datasets.
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IA-PACS-CFS: a double-blinded, randomized, sham-controlled, exploratory trial of immunoadsorption in patients with chronic fatigue syndrome (CFS) including patients with post-acute COVID-19 CFS (PACS-CFS).
Preßler, H., Machule, M.L., Ufer, F., Bünger, I., Li, L.Y., Buchholz, E., Werner, C., Beraha, E., Wagner, F., Metz, M., Burock, S., Bruckert, L., Franke, C., Wilck, N., Krüger, A., Reshetnik, A., Eckardt, K.U., Endres, M. and Prüss, H.
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Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome.
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Urinary CD4(+) T cells predict renal relapse in ANCA-associated vasculitis: results of the PRE-FLARED study.
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Comparison of Xrn1 and Rat1 5′ → 3′ exoribonucleases in budding yeast supports the specific role of Xrn1 in cotranslational mRNA decay.
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Delegation of the primary responsibility for MRI informed consent to technical assistants - findings from the NAKO health study.
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Selection on synonymous sites: the unwanted transcript hypothesis.
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Helmet radio frequency phased array applicators enhance thermal magnetic resonance of brain tumors.
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Multilayer nanocarrier for the codelivery of interferons: a promising strategy for biocompatible and long-acting antiviral treatment.
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Biomarker signatures associated with ageing free of major chronic diseases: results from a population-based sample of the EPIC-Potsdam cohort.
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Protease-activated receptor-1 IgG autoantibodies in patients with COVID-19.
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USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
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PITX2 deficiency leads to atrial mitochondrial dysfunction.
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Serotonin drives aggression and social behaviors of laboratory male mice in a semi-natural environment.
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18 September 2024
Renin is essential for angiotensin II formation in the brain.
Rodrigues, A.F., Domenig, O., Garrelds, I.M., Danser, J.A.H., Alenina, N., Poglitsch, M. and Bader, M.
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Angiotensin-(1-12): does it exist? A critical evaluation in humans, rats, and mice.
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Low income, being without employment, and living alone: how they are associated with cognitive functioning - results from the German national cohort (NAKO).
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Functional and evolutionary significance of unknown genes from uncultivated taxa.
Rodríguez Del Río, Á., Giner-Lamia, J., Cantalapiedra, C.P., Botas, J., Deng, Z., Hernández-Plaza, A., Munar-Palmer, M., Santamaría-Hernando, S., Rodríguez-Herva, J.J., Ruscheweyh, H.J., Paoli, L., Schmidt, T.S.B., Sunagawa, S., Bork, P., López-Solanilla, E., Coelho, L.P. and Huerta-Cepas, J.
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Shedding light on the D1‐like receptors: a fluorescence‐based toolbox for visualization of the D1 and D5 receptors.
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Does age protect against loss of tonotopy after acute deafness in adulthood?
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3 May 2024
Normal male fertility in a mouse model of KPNA2 deficiency.
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Karyopherin α2 is a maternal effect gene required for early embryonic development and female fertility in mice.
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Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
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11 April 2024
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts.
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Targeting HFpEF: unlocking the potential of glucagon receptor blockade.
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Discovery of antimicrobial peptides in the global microbiome with machine learning.
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11 July 2024
Mapping DHPS evolvability: identification of novel evolutionarily critical sub-structure through evolutionary and structural analyses of DHPS.
Sanyal, D., Shivram, A., Banerjee, S., Uversky, V.N., Chivukula, A., Chattopadhyay, K. and Chowdhury, S.
bioRxiv
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18 October 2024
Regimens and response assessment in minimally invasive image-guided therapies for vascular malformations: insights from a large cohort study at a tertiary-care hospital.
Savic, G.D., Torsello, G.F., Frisch, A., Wieners, G., Fehrenbach, U., Auer, T.A., Lüdemann, W.M., Gebauer, B. and Savic, L.J.
Life 14
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5 October 2024
Twisted-plywood-like tissue formation in vitro. Does curvature do the twist?
Schamberger, B., Ehrig, S., Dechat, T., Spitzer, S., Bidan, C.M., Fratzl, P., Dunlop, J.W.C. and Roschger, A.
PNAS Nexus 3
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April 2024
Decision-tree models indicative of microvascular invasion on MRI predict survival in patients with hepatocellular carcinoma following tumor ablation.
Schmidt, R., Hamm, C.A., Rueger, C., Xu, H., He, Y., Gottwald, L.A., Gebauer, B. and Savic, L.J.
Journal of Hepatocellular Carcinoma 11
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3 July 2024
SPIRE: a Searchable, Planetary-scale mIcrobiome REsource.
Schmidt, T.S.B., Fullam, A., Ferretti, P., Orakov, A., Maistrenko, O.M., Ruscheweyh, H.J., Letunic, I., Duan, Y., Van Rossum, T., Sunagawa, S., Mende, D.R., Finn, R.D., Kuhn, M., Pedro Coelho, L. and Bork, P.
Nucleic Acids Research 52
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5 January 2024
Host weight, seasonality and anthropogenic factors contribute to parasite community differences between urban and rural foxes.
Scholz, C., Jarquín-Díaz, V.H., Planillo, A., Radchuk, V., Scherer, C., Schulze, C., Ortmann, S., Kramer-Schadt, S. and Heitlinger, E.
Science of the Total Environment 936
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August 2024
Open-ST: high-resolution spatial transcriptomics in 3D.
Schott, M., León-Periñán, D., Splendiani, E., Strenger, L., Licha, J.R., Pentimalli, T.M., Schallenberg, S., Alles, J., Samut Tagliaferro, S., Boltengagen, A., Ehrig, S., Abbiati, S., Dommerich, S., Pagani, M., Ferretti, E., Macino, G., Karaiskos, N. and Rajewsky, N.
Cell 187
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25 July 2024
Impact of genetic test interpretation on a VPS13B missense variant in Cohen syndrome.
Schottmann, G., Martínez Almudéver, C., Knop, J.C.M., Suk, E.K., Meyer, Z., Kohlhase, J., Himmelreich, N., Kühnisch, J., Ott, C.E. and Seifert, W.
Frontiers in Neuroscience 18
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11 December 2024
Protein intake and type 2 diabetes mellitus: an umbrella review of systematic reviews for the evidence-based guideline for protein intake of the German Nutrition Society.
Schulze, M.B., Haardt, J., Amini, A.M., Kalotai, N., Lehmann, A., Schmidt, A., Buyken, A.E., Egert, S., Ellinger, S., Kroke, A., Kühn, T., Louis, S., Nimptsch, K., Schwingshackl, L., Siener, R., Zittermann, A., Watzl, B. and Lorkowski, S.
European Journal of Nutrition 63
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February 2024
ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling.
Scoyni, F., Sitnikova, V., Giudice, L., Korhonen, P., Trevisan, D.M., Hernandez de Sande, A., Gomez-Budia, M., Giniatullina, R., Ugidos, I.F., Dhungana, H., Pistono, C., Korvenlaita, N., Välimäki, N.N., Kangas, S.M., Hiltunen, A.E., Gribchenko, E., Kaikkonen-Määttä, M.U., Koistinaho, J., Ylä-Herttuala, S., Hinttala, R., Venø, M.T., Su, J., Stoffel, M., Schaefer, A., Rajewsky, N., Kjems, J., LaPierre, M.P., Piwecka, M., Jolkkonen, J., Giniatullin, R., Hansen, T.B. and Malm, T.
Cell Reports 43
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26 March 2024
Impairment of the adrenergic reserve associated with exercise intolerance in a murine model of heart failure with preserved ejection fraction.
Semmler, L., Jeising, T., Huettemeister, J., Bathe-Peters, M., Georgoula, K., Roshanbin, R., Sander, P., Fu, S., Bode, D., Hohendanner, F., Pieske, B., Annibale, P., Schiattarella, G.G., Oeing, C.U. and Heinzel, F.R.
Acta Physiologica 240
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April 2024
Advancing research and treatment: an overview of clinical trials in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and future perspectives.
Seton, K.A., Espejo-Oltra, J.A., Giménez-Orenga, K., Haagmans, R., Ramadan, D.J. and Mehlsen, J.
Journal of Clinical Medicine 13
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6 January 2024
Medium term (> 12 months) outcomes after laparoscopic hiatal hernia repair without conventional fundoplication using PH4B‑mesh implant (Phasix™) in 176 reflux patients: experience and technique.
Siemssen, B., Dahlke, P.M., Behrens, F., Hentschel, F. and Ibach, M.J.
Hernia 28
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October 2024
Cell swelling enhances ligand-driven β-adrenergic signaling.
Sirbu, A., Bathe-Peters, M., Kumar, J.L.M, Inoue, A., Lohse, M.J. and Annibale, P.
Nature Communications 15
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7 September 2024
Cell swelling enhances canonical β-adrenergic signaling.
Sirbu, A., Bathe-Peters, M., Kumar, J.L.M., Inoue, A., Lohse, M. and Annibale, P.
bioRxiv
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23 August 2024
Modern perspective of the rice diet for hypertension and other metabolic diseases.
Sommerfeld, R., Ermler, P., Fehr, J., Bergner, B., Lopez, D., Sanoff, S., Neelon, F.A., Kuo, A., McDowell, W., Li, Y.J., Fox, S., Ghajar, A., Gensch, E., Lorenz, C., Preiss, M., Richter, T., Luft, F.C., Klemmer, P., Bohannon, A., Lippert, C. and Lin, P.H.
BMJ Nutrition Prevention & Health 7
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December 2024
Angiotensin-(1-5) is a potent endogenous angiotensin AT(2)-receptor agonist.
Souza-Silva, I.M., Peluso, A.A., Elsaafien, K., Nazarova, A.L., Assersen, K.B., Rodrigues-Ribeiro, L., Mohammed, M., Rodrigues, A.F., Nawrocki, A., Johansen, L.A., Jensen, P., de Kloet, A.D., Krause, E.G., DelBorgo, M., Maslov, I., Widdop, R.E., Santos, R.A., Bader, M., Larsen, M.R., Verano-Braga, T., Katritch, V., Sumners, C. and Steckelings, U.M.
bioRxiv
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18 April 2024
Telemonitoring for chronic heart failure: narrative review of the 20-year journey from concept to standard care in Germany.
Spethmann, S., Hindricks, G., Koehler, K., Stoerk, S., Angermann, C.E., Böhm, M., Assmus, B., Winkler, S., Mökel, M., Mittermaier, M., Lelgemann, M., Reuter, D., Bosch, R., Albrecht, A., von Haehling, S., Helms, T.M., Sack, S., Bekfani, T., Gröschel, J.W., Koehler, M., Melzer, C., Wintrich, J., Zippel-Schultz, B., Ertl, G., Vogelmeier, C., Dagres, N., Zernikow, J. and Koehler, F.
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4 December 2024
Hypertensive disorders of pregnancy and cardiovascular disease risk.
Staff, A.C., Dechend, R. and Jacobsen, D.P.
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Manual of Cardiovascular Disease in Women.
Springer Nature Switzerland, Cham, Switzerland, 119-141.
ISBN 978-3-031-65952-2
28 September 2024
Hypertensive disorders of pregnancy and long-term maternal cardiovascular risk: bridging epidemiological knowledge into personalized postpartum care and follow-up.
Staff, A.C., Costa, M.L., Dechend, R., Jacobsen, D.P. and Sugulle, M.
Pregnancy Hypertension 36
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June 2024
The challenges of research data management in cardiovascular science: a DGK and DZHK position paper-executive summary.
Steffens, S., Schröder, K., Krüger, M., Maack, C., Streckfuss-Bömeke, K., Backs, J., Backofen, R., Baeßler, B., Devaux, Y., Gilsbach, R., Heijman, J., Knaus, J., Kramann, R., Linz, D., Lister, A.L., Maatz, H., Maegdefessel, L., Mayr, M., Meder, B., Nussbeck, S.Y., Rog-Zielinska, E.A., Schulz, M.H., Sickmann, A., Yigit, G. and Kohl, P.
Clinical Research in Cardiology 113
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May 2024
Cryosectioning-enabled super-resolution microscopy for studying nuclear architecture at the single protein level.
Stein, J., Ericsson, M., Nofal, M., Magni, L., Aufmkolk, S., McMillan, R.B., Breimann, L., Herlihy, C.P., Lee, S.D., Willemin, A., Wohlmann, J., Arguedas-Jimenez, L., Yin, P., Pombo, A., Church, G.M. and Wu, C.T.
bioRxiv
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5 February 2024
Differences in anthropometric measures based on sex, age, and health status: findings from the German National Cohort (NAKO).
Stein, M.J., Fischer, B., Bohmann, P., Ahrens, W., Berger, K., Brenner, H., Günther, K., Harth, V., Heise, J.K., Karch, A., Klett-Tammen, C.J., Koch-Gallenkamp, L., Krist, L., Lieb, W., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Nimptsch, K., Obi, N., Peters, A., Pischon, T., Schipf, S., Schmidt, B., Stang, A., Thierry, S., Willich, S.N., Wirkner, K., Leitzmann, M.F. and Sedlmeier, A.M.
Deutsches Arzteblatt International 121
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5 April 2024
Systems biology approach uncovers candidates for liver-heart interorgan crosstalk in HFpEF.
Strocchi, S., Liu, L., Wang, R., Häseli, S.P., Capone, F., Bode, D., Nambiar, N., Eroglu, T., Santiago Padilla, L., Farrelly, C., Vacca, A., Mascagni, M., Oeing, C.U., Kintscher, U., Jung, S., Diezel, S.A., Liévano Contreras, S.V., Zhou, M., Seldin, M. and Schiattarella, G.G.
Circulation Research 135
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27 September 2024
Titin's cardiac-specific N2B element is critical to mechanotransduction during volume overload of the heart.
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Journal of Molecular and Cellular Cardiology 191
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June 2024
EU-LIFE charter of independent life science research institutes.
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FEBS Letters 598
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April 2024
Macrocephaly and digital anomalies expand the phenotypic spectrum of PGAP2 variants in hyperphosphatasia with impaired intellectual development syndrome 3 (HPMRS3).
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Human Mutation 2024
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5 January 2024
Interleukin 11 therapy causes acute left ventricular dysfunction.
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Cardiovascular Research 120
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December 2024
Plasma NGAL levels in stable kidney transplant recipients and the risk of allograft loss.
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Nephrology Dialysis Transplantation 39
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March 2024
A single dose of cocaine rewires the 3D genome structure of midbrain dopamine neurons.
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bioRxiv
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12 May 2024
Protein biomarkers of adverse clinical features and events in sarcomeric hypertrophic cardiomyopathy.
Tahir, U.A., Kolm, P., Kwong, R.Y., Desai, M.Y., Dolman, S.F., Deng, S., Appelbaum, E., Desvigne-Nickens, P., DiMarco, J.P., Tiwari, G., Friedrich, M.G., Zelaya-Portillo, J.H., Jerosch-Herold, M., Kim, D.Y., Maron, M.S., Piechnik, S.K., Schulz-Menger, J., Watkins, H., Weintraub, W.S., Neubauer, S., Kramer, C.M., Jarolim, P., Gerszten, R.E. and Ho, C.Y.
Circulation Heart Failure 17
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In vivo monitoring of renal tubule volume fraction using dynamic parametric MRI.
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Magnetic Resonance in Medicine 91
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June 2024
Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.
Teixeira Alves, L.G., Baumgardt, M., Langner, C., Fischer, M., Maria Adler, J., Bushe, J., Firsching, T.C., Mastrobuoni, G., Grobe, J., Hoenzke, K., Kempa, S., Gruber, A.D., Hocke, A.C., Trimpert, J., Wyler, E. and Landthaler, M.
BMJ Open Respiratory Research 11
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29 February 2024
Precision fMRI and cluster-failure in the individual brain.
Tellez Ceja, I.F., Gladytz, T., Starke, L., Tabelow, K., Niendorf, T. and Reimann, H.M.
Human Brain Mapping 45
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15 August 2024
RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth.
Tetik-Elsherbiny, N., Elsherbiny, A., Setya, A., Gahn, J., Tang, Y., Gupta, P., Dou, Y., Serke, H., Wieland, T., Dubrac, A., Heineke, J., Potente, M., Cordero, J., Ola, R. and Dobreva, G.
Nature Cardiovascular Research 3
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October 2024
Review: Opportunities and barriers for omics-based biomarker discovery in steatotic liver diseases.
Thiele, M., Villesen, I.., Niu, L., Johansen, S., Sulek, K., Nishijima, S., Van Espen, L., Keller, M., Israelsen, M., Suvitaival, T., de Zawadzki, A., Juel, H.B., Brol, M.J., Stinson, S.E., Huang, Y., Alvarez Silva, M.C., Kuhn, M., Anastasiadou, E., Leeming, D.J., Karsdal, M., Matthijnssens, J., Arumugam, M., Dalgaard, L.T., Legido-Quigley, C., Mann, M., Trebicka, J., Bork, P., Jensen, L.J., Hansen, T. and Krag, A.
Journal of Hepatology 81
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August 2024
A systematic review of observational studies on the association between diet quality patterns and visceral adipose tissue.
Thimm, A., Maskarinec, G., Guillermo, C., Nimptsch, K. and Pischon, T.
British Journal of Nutrition 132
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14 December 2024
The influence of post-processing software on quantitative results in 4D flow cardiovascular magnetic resonance examinations.
Trauzeddel, R.F., Müller, M., Demir, A., Wiesemann, S., Daud, E., Schmitter, S., Viezzer, D., Hadler, T. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 11
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27 September 2024
Histone H3.3 lysine 9 and 27 control repressive chromatin at cryptic enhancers and bivalent promoters.
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Nature Communications 15
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30 August 2024
KCNQ5 controls perivascular adipose tissue–mediated vasodilation.
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Hypertension 81
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March 2024
Lifestyle interventions in cardiometabolic HFpEF: dietary and exercise modalities.
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16 September 2024
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From gut to heart: role of indole-3-propionic acid in HFpEF.
Vacca, A. and Schiattarella, G.G.
Circulation Research 134
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16 February 2024
Loss of cardiac splicing regulator RBM20 is associated with early-onset atrial fibrillation.
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JACC: Basic to Translational Science 9
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February 2024
Bifidobacterium and lactobacillus probiotics and gut dysbiosis in preterm infants: the PRIMAL randomized clinical trial.
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JAMA Pediatrics 178
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Reslice3Dto2D: Introduction of a software tool to reformat 3D volumes into reference 2D slices in cardiovascular magnetic resonance imaging.
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BMC Research Notes 17
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Post-hoc standardisation of parametric T1 maps in cardiovascular magnetic resonance imaging: a proof-of-concept.
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EBioMedicine 102
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April 2024
The IsletTester mouse: an immunodeficient model with stable hyperglycemia for the study of human islets.
Waite, E.L., Tigue, M., Yu, M., Lahori, D., Kelly, K., May, C.L., Naji, A., Roman, J., Doliba, N., Avrahami, D., Nguyen-Ngoc, K.V., Sander, M., Glaser, B. and Kaestner, K.H.
Diabetes
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Generation and downstream analysis of single-cell and single-nuclei transcriptomes in brain organoids.
Wandres, M., Aigner, D., Kastelic, N., Boltengagen, A., Rybak-Wolf, A. and Rajewsky, N.
Journal of Visualized Experiments
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29 March 2024
Socio-affective communication in Tph2-deficient rat pups: communal nesting aggravates growth retardation despite ameliorating maternal affiliation deficits.
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Molecular Autism 15
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Cross-platform clinical proteomics using the Charité Open Standard for Plasma Proteomics (OSPP).
Wang, Z., Farztdinov, V., Sinn, L.R., Tober-Lau, P., Ludwig, D., Freiwald, A., Amari, F., Textoris-Taube, K., Niewienda, A., Welter, A.S., Wei, A.A.J., Luckau, L., Kurth, F., Selbach, M., Hartl, J., Mülleder, M. and Ralser, M.
medRxiv
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10 May 2024
Tackling metabolic defects in HFpEF.
Wang, R. and Schiattarella, G.G.
European Heart Journal 45
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1 May 2024
Incidence of Parkinson’s disease in Germany based on prevalence data from 70 million patients of the statutory health insurance.
Wattenbach, C., Ellrichmann, G., Feinkohl, I., Voß, S. and Brinks, R.
BMC Neurology 24
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27 June 2024
The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells.
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bioRxiv
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31 October 2024
Large‑scale assessment of physical activity in a population using high‑resolution hip‑worn accelerometry: the German National Cohort (NAKO).
Weber, A., van Hees, V.T., Stein, M.J., Gastell, S., Steindorf, K., Herbolsheimer, F., Ostrzinski, S., Pischon, T., Brandes, M., Krist, L., Marschollek, M., Greiser, K.H., Nimptsch, K., Brandes, B., Jochem, C., Sedlmeier, A.M., Berger, K., Brenner, H., Buck, C., Castell, S., Dörr, M., Emmel, C., Fischer, B., Flexeder, C., Harth, V., Hebestreit, A., Heise, J.K., Holleczek, B., Keil, T., Koch-Gallenkamp, L., Lieb, W., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Kluttig, A., Obi, N., Peters, A., Schmidt, B., Schipf, S., Schulze, M.B., Teismann, H., Waniek, S., Willich, S.N., Leitzmann, M.F. and Baurecht, H.
Scientific Reports 14
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4 April 2024
Combining Data Independent Acquisition with spike-in SILAC (DIA-SiS) improves proteome coverage and quantification.
Welter, A.S., Gerwien, M., Kerridge, R., Alp, K.M., Mertins, P. and Selbach, M.
Molecular & Cellular Proteomics 23
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October 2024
TPT-004, a next-generation inhibitor of tryptophan hydroxylase, ameliorates pulmonary arterial hypertension in rats.
Wesolowski, R., Pleimes, D., Specker, E. and Bader, M.
Journal of the American Heart Association 13
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21 May 2024
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
Widjaja, A.A., Lim, W.W., Viswanathan, S., Chothani, S., Corden, B., Dasan, C.M., Goh, J.W.T., Lim, R., Singh, B.K., Tan, J., Pua, C.J., Lim, S.Y., Adami, E., Schafer, S., George, B.L., Sweeney, M., Xie, C., Tripathi, M., Sims, N.A., Hübner, N., Petretto, E., Withers, D.J., Ho, L., Gil, J., Carling, D. and Cook, S.A.
Nature 632
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Health service use among migrants in the German National Cohort - the role of birth region and language skills.
Wiessner, C., Licaj, S., Klein, J., Bohn, B., Brand, T., Castell, S., Führer, A., Harth, V., Heier, M., Heise, J.K., Holleczek, B., Jaskulski, S., Jochem, C., Koch-Gallenkamp, L., Krist, L., Leitzmann, M., Lieb, W., Meinke-Franze, C., Mikolajczyk, R., Moreno Velásquez, I., Obi, N., Pischon, T., Schipf, S., Thierry, S., Willich, S.N., Zeeb, H. and Becher, H.
International Journal of Public Health 69
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Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells.
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Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
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Current practice of blood pressure measurement in Germany: a nationwide questionnaire-based survey in medical practices.
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Towards monitoring of antimicrobial resistance in the environment: For what reasons, how to implement it, and what are the data needs?
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Myocardial injury in patients with acute ischemic stroke detected by cardiovascular magnetic resonance imaging.
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Combining metabolic pulse labeling and quantitative proteomics to monitor protein synthesis upon viral infection.
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90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection.
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Fluid shear stress induces a shift from glycolytic to amino acid pathway in human trophoblasts.
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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
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LRP2 contributes to planar cell polarity-dependent coordination of motile cilia function.
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Nonsense mediated decay factor UPF3B is associated with cMyBP-C haploinsufficiency in hypertrophic cardiomyopathy patients.
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Autoantibodies targeting G protein-coupled receptors: an evolving history in autoimmunity. Report of the 4th international symposium.
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AT1-AA infusion during pregnancy impairs CBF autoregulation postpartum.
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Monitoring kidney size to interpret MRI-based assessment of renal oxygenation in acute pathophysiological scenarios.
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Cardiometabolic HFpEF: NASH of the heart.
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Impact of high salt-intake on a natural gut ecosystem in wildling mice.
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Cerebrovascular G(i) proteins protect against brain hypoperfusion and collateral failure in cerebral ischemia.
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Brown adipose tissue transcriptome unveils an important role of the Beta-alanine/alamandine receptor, MrgD, in metabolism.
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Dipeptidyl peptidase 1 inhibition as a potential therapeutic approach in neutrophil-mediated inflammatory disease.
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LongDat: an R package for covariate-sensitive longitudinal analysis of high-dimensional data.
Chen, C.Y., Löber, U. and Forslund, S.K.
Bioinformatics Advances 3
(1): vbad063.
18 May 2023
A guide to naming eukaryotic circular RNAs.
Chen, L.L., Bindereif, A., Bozzoni, I., Chang, H.Y., Matera, A.G., Gorospe, M., Hansen, T.B., Kjems, J., Ma, X.K., Pek, J.W., Rajewsky, N., Salzman, J., Wilusz, J.E., Yang, L. and Zhao, F.
Nature Cell Biology 25
(1): 1-5.
January 2023
Novel candidate regulators and developmental trajectory of pituitary thyrotropes.
Cheung, L.Y.M., Menage, L., Rizzoti, K., Hamilton, G., Dumontet, T., Basham, K., Daly, A.Z., Brinkmeier, M.L., Masser, B.E., Treier, M., Cobb, J., Delogu, A., Lovell-Badge, R., Hammer, G.D. and Camper, S.A.
Endocrinology 164
(6): bqad076.
June 2023
Physics-based polymer models to probe chromosome structure in single molecules.
Conte, M., Chiariello, A.M., Bianco, S., Esposito, A., Abraham, A. and Nicodemi, M.
Methods in Molecular Biology 2655
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2023
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.
Costanzo, M.C., von Grotthuss, M., Massung, J., Jang, D., Caulkins, L., Koesterer, R., Gilbert, C., Welch, R.P., Kudtarkar, P., Hoang, Q., Boughton, A.P., Singh, P., Sun, Y., Duby, M., Moriondo, A., Nguyen, T., Smadbeck, P., Alexander, B.R., Brandes, M.K., Carmichael, M., Dornbos, P., Green, T., Huellas-Bruskiewicz, K.C., Ji, Y., Kluge, A., McMahon, A.C., Mercader, J.M., Ruebenacker, O., Sengupta, S., Spalding, D., Taliun, D., Smith, P., Thomas, M.K., Akolkar, B., Brosnan, M.J., Cherkas, A., Chu, A.Y., Fauman, E.B., Fox, C.S., Kamphaus, T.N., Miller, M.R., Nguyen, L., Parsa, A., Reilly, D.F., Ruetten, H., Wholley, D., Zaghloul, N.A., Abecasis, G.R., Altshuler, D., Keane, T.M., McCarthy, M.I., Gaulton, K.J., Florez, J.C., Boehnke, M., Burtt, N.P. and Flannick, J.
Cell Metabolism 35
(4): 695-710.e6.
4 April 2023
Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing.
Cui, L., Yang, B., Xiao, S., Gao, J., Baud, A., Graham, D., McBride, M., Dominiczak, A., Schafer, S., Aumatell, R.L., Mont, C., Teruel, A.F., Hübner, N., Flint, J., Mott, R. and Huang, L.
Genome Biology 24
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29 September 2023
Arterial myogenic response and aging.
Cui, Y., Gollasch, M. and Kassmann, M.
Ageing Research Reviews 84
: 101813.
February 2023
Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.
Côrte-Real, B.F., Hamad, I., Arroyo Hornero, R., Geisberger, S., Roels, J., Van Zeebroeck, L., Dyczko, A., van Gisbergen, M.W., Kurniawan, H., Wagner, A., Yosef, N., Weiss, S.N.Y., Schmetterer, K.G., Schröder, A., Krampert, L., Haase, S., Bartolomaeus, H., Hellings, N., Saeys, Y., Dubois, L.J., Brenner, D., Kempa, S., Hafler, D.A., Stegbauer, J., Linker, R.A., Jantsch, J., Müller, D.N. and Kleinewietfeld, M.
Cell Metabolism 35
(2): 299-315.
7 February 2023
Atrial natriuretic peptide and leptin interactions in healthy men.
Daniels, M.A., Fischer-Posovszky, P., Boschmann, M., Jumpertz-von Schwartzenberg, R., Müller, T.D., Sandforth, L., Frank-Podlech, S., Hülskämper, S., Peter, A., Wabitsch, M., Jordan, J. and Birkenfeld, A.L.
Frontiers in Endocrinology 14
: 1195677.
30 June 2023
External mechanical loading overrules cell-cell mechanical communication in sprouting angiogenesis during early bone regeneration.
Dazzi, C., Mehl, J., Benamar, M., Gerhardt, H., Knaus, P., Duda, G.N. and Checa, S.
PLoS Computational Biology 19
(11): e1011647.
13 November 2023
Influenzaimpfung – Mehr als nur Influenzaschutz [Influenza vaccination – more than just protection against the flu].
Dechend, R.
Kardiologie 17
(6): 434-440.
December 2023
In vitro galactose impairs energy metabolism in the brain of young rats: protective role of antioxidants.
Delwing-de Lima, D., Sasso, S., Delwing-Dal Magro, D., Pereira, N.R., Rodrigues, A.F., Schmitz, F., Manoel Pereira, E., Schramm do Nascimento, M.A. and Wyse, A.T.S.
Nucleosides Nucleotides & Nucleic Acids 42
(12): 967-985.
2023
HMGXB4 targets Sleeping Beauty transposition to germinal stem cells.
Devaraj, A., Singh, M., Narayanavari, S.A., Yong, G., Chen, J., Wang, J., Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z., Raskó, T., Radscheit, K., Selbach, M., Ivics, Z. and Izsvak, Z.
International Journal of Molecular Sciences 24
(8): 7283.
14 April 2023
Liver resection modulates hepatic chemokine levels in breast cancer.
Dincer, H.A., Horzum, U., Kursunel, M.A., Yoyen-Ermis, D., Ermis, E., Ozogul, E., Akkapulu, N., Esendagli, G. and Karakoc, D.
Surgery 174
(2): 277-282.
August 2023
Old discovery leading to new era: metabolic imaging of cancer with Deuterium MRI.
Ding, H., Haroon, A., Wan, S., Niendorf, T. and Adeleke, S.
Magnetochemistry 9
(1): 6.
January 2023
Trends and perspectives for improving quality of chronic kidney disease care: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Eckardt, K.U., Delgado, C., Heerspink, H.J.L., Pecoits-Filho, R., Ricardo, A.C., Stengel, B., Tonelli, M., Cheung, M., Jadoul, M., Winkelmayer, W.C. and Kramer, H.
Kidney International 104
(5): 888-903.
November 2023
Kommentar zu den Leitlinien 2022 der ESC zu ventrikulären Arrhythmien und Prävention des plötzlichen Herztodes [Comments on the 2022 guidelines of the ESC on ventricular arrhythmias and prevention of sudden cardiac death].
Eckardt, L., Könemann, H., Bosch, R., Deneke, T., Falk, V., Perings, C., Schulz-Menger, J. and Meyer, C.
Kardiologie 17
(1): 27-38.
3 February 2023
Mutations in phosphodiesterase 3A (PDE3A) cause hypertension without cardiac damage.
Ercu, M., Walter, S. and Klussmann, E.
Hypertension 80
(6): 1171-1179.
June 2023
High tissue-sodium associates with systemic inflammation and insulin resistance in obese individuals.
Ertuglu, L., Sahinoz, M., Alsouqi, A., Deger, S.M., Guide, A., Stewart, T.G., Pike, M., Robinson-Cohen, C., Akwo, E., Pridmore, M., Crescenzi, R., Madhur, M.S., Harrison, D.G., Luft, F.C., Titze, J. and Ikizler, T.A.
Nutrition Metabolism and Cardiovascular Diseases 33
(7): 1398-1406.
July 2023
Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging.
Espiritu, J., Berangi, M., Cwieka, H., Iskhakova, K., Kuehne, A., Florian Wieland, D.C., Zeller-Plumhoff, B., Niendorf, T., Willumeit-Römer, R. and Seitz, J.M.
Bioactive Materials 25
: 86-94.
23 January 2023
Spatially and temporally distinct patterns of expression for VPS10P domain receptors in human cerebral organoids.
Febbraro, F., Andersen, H.H.B., Kitt, M.M. and Willnow, T.E.
Frontiers in Cell and Developmental Biology 11
: 2023.
29 September 2023
Metabolic syndrome and the risk of postoperative delirium and postoperative cognitive dysfunction: a multi-centre cohort study.
Feinkohl, I., Janke, J., Slooter, A.J.C., Winterer, G., Spies, C. and Pischon, T.
British Journal of Anaesthesia 131
(2): 338-347.
August 2023
Stellenwert der kardialen MRT bei Patienten mit ventrikulären Arrhythmien und zur Prävention des plötzlichen Herztods [Role of cardiovascular MRI in patients with ventricular arrhythmias and prevention of sudden cardiac death].
Fenski, M., Krüger, L.D. and Schulz-Menger, J.
Aktuelle Kardiologie 12
(03): 199-206.
6 June 2023
Amplicon sequencing allows differential quantification of closely related parasite species: an example from rodent Coccidia (Eimeria).
Ferreira, S.C.M., Jarquín-Díaz, V.H. and Heitlinger, E.
Parasites and Vectors 16
(1): 204.
17 June 2023
Cardiovascular magnetic resonance for evaluation of cardiac involvement in COVID-19: recommendations by the Society for Cardiovascular Magnetic Resonance.
Ferreira, V.M., Plein, S., Wong, T.C., Tao, Q., Raisi-Estabragh, Z., Jain, S.S., Han, Y., Ojha, V., Bluemke, D.A., Hanneman, K., Weinsaft, J., Vidula, M.K., Ntusi, N. A.B., Schulz-Menger, J. and Kim, J.
Journal of Cardiovascular Magnetic Resonance 25
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27 March 2023
Heart development and regeneration -- a multi‐organ effort.
Filosa, A. and Sawamiphak, S.
FEBS Journal 290
(4): 913-930.
February 2023
Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma.
Finotto, L., Cole, B., Giese, W., Baumann, E., Claeys, A., Vanmechelen, M., Decraene, B., Derweduwe, M., Dubroja Lakic, N., Shankar, G., Nagathihalli Kantharaju, M., Albrecht, J.P., Geudens, I., Stanchi, F., Ligon, K.L., Boeckx, B., Lambrechts, D., Harrington, K., Van Den Bosch, L., De Vleeschouwer, S., De Smet, F. and Gerhardt, H.
EMBO Molecular Medicine 15
(11): e18144.
8 November 2023
Identification of radiomic biomarkers in a set of four skeletal muscle groups on Dixon MRI of the NAKO MR study.
Fischer, M., Küstner, T., Pappa, S., Niendorf, T., Pischon, T., Kröncke, T., Bette, S., Schramm, S., Schmidt, B., Haubold, J., Nensa, F., Nonnenmacher, T., Palm, V., Bamberg, F., Kiefer, L., Schick, F. and Yang, B.
BMC Medical Imaging 23
(1): 104.
8 August 2023
Trail making test B in postoperative delirium: a replication study.
Fislage, M., Feinkohl, I., Borchers, F., Heinrich, M., Pischon, T., Veldhuijzen, D.S., Slooter, A.J.C., Spies, C.D., Winterer, G. and Zacharias, N.
BJA Open 8
: 100239.
December 2023
Preoperative thalamus volume is not associated with preoperative cognitive impairment (preCI) or postoperative cognitive dysfunction (POCD).
Fislage, M., Feinkohl, I., Borchers, F., Pischon, T., Spies, C.D., Winterer, G. and Zacharias, N.
Scientific Reports 13
(1): 11732.
20 July 2023
The thalamus in perioperative neurocognitive disorders.
Fislage, M., Zacharias, N. and Feinkohl, I.
Neuropsychology Review 34
(3): 850-859.
September 2023
A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions.
Fonseca, C.G., Silvério, V., Barata, D., Giese, W., Gerhardt, H., Cardoso, S. and Franco, C.A.
Microsystems & Nanoengineering 9
: 114.
15 September 2023
Fasting intervention and its clinical effects on the human host and microbiome.
Forslund, S.K.
Journal of Internal Medicine 293
(2): 166-183.
February 2023
CD39 abrogates platelet-derived factors induced IL-1β expression in the human placenta.
Forstner, D., Guettler, J., Brugger, B.A., Lyssy, F., Neuper, L., Daxboeck, C., Cvirn, G., Fuchs, J., Kraeker, K., Frolova, A., Valdes, D.S., Stern, C., Hirschmugl, B., Fluhr, H., Wadsack, C., Huppertz, B., Nonn, O., Herse, F. and Gauster, M.
Frontiers in Cell and Developmental Biology 11
: 1183793.
2023
Molecular mechanisms underlying the beneficial effects of exercise and dietary interventions in the prevention of cardiometabolic diseases.
Forte, M., Rodolico, D., Ameri, P., Catalucci, D., Chimenti, C., Crotti, L., Schirone, L., Pingitore, A., Torella, D., Iacovone, G., Valenti, V., Schiattarella, G.G., Perrino, C. and Sciarretta, S.
Journal of Cardiovascular Medicine 24
(Suppl 1): e3-e14.
1 April 2023
CAR links hypoxia signaling to improved survival after myocardial infarction.
Freiberg, F., Thakkar, M., Hamann, W., Lopez Carballo, J., Jüttner, R., Voss, F.K., Becher, P.M., Westermann, D., Tschöpe, C., Heuser, A., Rocks, O., Fischer, R. and Gotthardt, M.
Experimental and Molecular Medicine 55
(3): 643-652.
March 2023
Three-dimensional histological characterization of the placental vasculature using light sheet microscopy.
Freise, L., Behncke, R.Y., Allerkamp, H.H., Sandermann, T.H., Chu, N.H., Funk, E.M., Hondrich, L.J., Riedel, A., Witzel, C., Hansmeier, N.R., Danyel, M., Gellhaus, A., Dechend, R. and Hägerling, R.
Biomolecules 13
(6): 1009.
17 June 2023
Modeling IP(3)-induced Ca(2+) signaling based on its interspike interval statistics.
Friedhoff, V.N., Lindner, B. and Falcke, M.
Biophysical Journal 122
(13): 2818-2831.
11 July 2023
Fiber-orientation independent component of R(2)* obtained from single-orientation MRI measurements in simulations and a post-mortem human optic chiasm.
Fritz, F.J., Mordhorst, L., Ashtarayeh, M., Periquito, J., Pohlmann, A., Morawski, M., Jaeger, C., Niendorf, T., Pine, K.J., Callaghan, M.F., Weiskopf, N. and Mohammadi, S.
Frontiers in Neuroscience 17
: 1133086.
25 August 2023
C. elegans gene regulatory alleles and reporter bashing studies.
Froehlich, J.J. and Rajewsky, N.
microPublication Biology 2023
20 January 2023
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S., Danßmann, C., Klironomos, F., Winkler, A., Fallmann, J., Kruetzfeldt, L.M., Szymansky, A., Naderi, J., Bernhart, S.H., Grunewald, L., Helmsauer, K., Rodriguez-Fos, E., Kirchner, M., Mertins, P., Astrahantseff, K., Suenkel, C., Toedling, J., Meggetto, F., Remke, M., Stadler, P.F., Hundsdoerfer, P., Deubzer, H.E., Künkele, A., Lang, P., Fuchs, J., Henssen, A.G., Eggert, A., Rajewsky, N., Hertwig, F. and Schulte, J.H.
Nature Communications 14
(1): 3936.
4 July 2023
proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes.
Fullam, A., Letunic, I., Schmidt, T.S.B., Ducarmon, Q.R., Karcher, N., Khedkar, S., Kuhn, M., Larralde, M., Maistrenko, O.M., Malfertheiner, L., Milanese, A., Rodrigues, J.F.M., Sanchis-López, C., Schudoma, C., Szklarczyk, D., Sunagawa, S., Zeller, G., Huerta-Cepas, J., von Mering, C., Bork, P. and Mende, D.R.
Nucleic Acids Research 51
(D1): D760-D766.
6 January 2023
Regulation of prostate androgens by megalin and 25-hydroxyvitamin D status: mechanism for high prostate androgens in African American men.
Garcia, J., Krieger, K.D., Loitz, C., Perez, L.M., Richards, Z.A., Helou, Y., Kregel, S., Celada, S., Mesaros, C.A., Bosland, M., Gann, P.H., Willnow, T.E., Vander Griend, D., Kittles, R., Prins, G.S., Penning, T. and Nonn, L.
Cancer Research Communications 3
(3): 371–382.
3 March 2023
Better together: data harmonization and cross-study analysis of abdominal MRI data from UK Biobank and the German National Cohort.
Gatidis, S., Kart, T., Fischer, M., Winzeck, S., Glocker, B., Bai, W., Bülow, R., Emmel, C., Friedrich, L., Kauczor, H.U., Keil, T., Kröncke, T., Mayer, P., Niendorf, T., Peters, A., Pischon, T., Schaarschmidt, B.M., Schmidt, B., Schulze, M.B., Umutle, L., Völzke, H., Küstner, T., Bamberg, F., Schölkopf, B. and Rueckert, D.
Investigative Radiology 58
(5): 346-354.
1 May 2023
Quantitative morphological analysis of the T-tubular network of ventricular cardiomyocytes using novel image processing tools.
Georgoula, K., Sage, D. and Annibale, P.
In: European Conferences on Biomedical Optics 2023, 25-29 June 2023, Munich, Germany.
11 August 2023
"suMus," a novel digital system for arm movement metrics and muscle energy expenditure.
Gerhalter, Teresa, Müller, Christina, Maron, Elke, Thielen, Markus, Schätzl, Teresa, Mähler, A., Schütte, T., Boschmann, M., Herzer, René, Spuler, S. and Gazzerro, E.
Frontiers in Physiology 14
: 1057592.
26 January 2023
The effect of probiotic and synbiotic supplementation on lipid parameters among patients with cardiometabolic risk factors: a systematic review and meta-analysis of clinical trials.
Ghorbani, Z., Kazemi, A., Bartolomaeus, T.U.P., Martami, F., Noormohammadi, M., Salari, A., Löber, U., Balou, H.A., Forslund, S.K. and Mahdavi-Roshan, M.
Cardiovascular Research 119
(4): 933-956.
April 2023
Cardiac splicing as a diagnostic and therapeutic target.
Gotthardt, M., Badillo Lisakowski, V., Parikh, V.N., Ashley, E., Furtado, M., Carmo-Fonseca, M., Schudy, S., Meder, B., Grosch, M., Steinmetz, L., Crocini, C. and Leinwand, L.
Nature Reviews Cardiology 20
(8): 517-530.
August 2023
HNF1B alters an evolutionarily conserved nephrogenic program of target genes.
Grand, K., Stoltz, M., Rizzo, L., Röck, R., Kaminski, M.M., Salinas, G., Getwan, M., Naert, T., Pichler, R. and Lienkamp, S.S.
Journal of the American Society of Nephrology 34
(3): 412-432.
March 2023
A consensus protocol for functional connectivity analysis in the rat brain.
Grandjean, J., Desrosiers-Gregoire, G., Anckaerts, C., Angeles-Valdez, D., Ayad, F., Barrière, D.A., Blockx, I., Bortel, A., Broadwater, M., Cardoso, B.M., Célestine, M., Chavez-Negrete, J.E., Choi, S., Christiaen, E., Clavijo, P., Colon-Perez, L., Cramer, S., Daniele, T., Dempsey, E., Diao, Y., Doelemeyer, A., Dopfel, D., Dvořáková, L., Falfán-Melgoza, C., Fernandes, F.F., Fowler, C.F., Fuentes-Ibañez, A., Garin, C.M., Gelderman, E., Golden, C.E.M., Guo, C.C G., Henckens, M.J.A.G., Hennessy, L.A., Herman, P., Hofwijks, N., Horien, C., Ionescu, T.M., Jones, J., Kaesser, J., Kim, E., Lambers, H., Lazari, A., Lee, S.H., Lillywhite, A., Liu, Y., Liu, Y.Y., López-Castro, A., López-Gil, X., Ma, Z., MacNicol, E., Madularu, D., Mandino, F., Marciano, S., McAuslan, M.J., McCunn, P., McIntosh, A., Meng, X., Meyer-Baese, L., Missault, S., Moro, F., Naessens, D.M.P., Nava-Gomez, L.J., Nonaka, H., Ortiz, J.J., Paasonen, J., Peeters, L.M., Pereira, M., Perez, P.D., Pompilus, M., Prior, M., Rakhmatullin, R., Reimann, H.M., Reinwald, J., Del Rio, R.T., Rivera-Olvera, A., Ruiz-Pérez, D., Russo, G., Rutten, T.J., Ryoke, R., Sack, M., Salvan, P., Sanganahalli, B.G., Schroeter, A., Seewoo, B.J., Selingue, E., Seuwen, A., Shi, B., Sirmpilatze, N., Smith, J.A.B., Smith, C., Sobczak, F., Stenroos, P.J., Straathof, M., Strobelt, S., Sumiyoshi, A., Takahashi, K., Torres-García, M.E, Tudela, R., van den Berg, M., van der Marel, K., van Hout, A.T.B., Vertullo, R., Vidal, B., Vrooman, R.M., Wang, V.X., Wank, I., Watson, D.J.G., Yin, T., Zhang, Y., Zurbruegg, S., Achard, S., Alcauter, S., Auer, D.P., Barbier, E.L., Baudewig, J., Beckmann, C.F., Beckmann, N., Becq, G.J.P.C., Blezer, E.L.A., Bolbos, R., Boretius, S., Bouvard, S., Budinger, E., Buxbaum, J.D., Cash, D., Chapman, V., Chuang, K.H., Ciobanu, L., Coolen, B.F., Dalley, J.W., Dhenain, M., Dijkhuizen, R.M., Esteban, O., Faber, C., Febo, M., Feindel, K.W., Forloni, G., Fouquet, J., Garza-Villarreal, E.A., Gass, N., Glennon, J.C., Gozzi, A., Gröhn, O., Harkin, A., Heerschap, A., Helluy, X., Herfert, K., Heuser, A., Homberg, J.R., Houwing, D.J., Hyder, F., Ielacqua, G.D., Jelescu, I.O., Johansen-Berg, H., Kaneko, G., Kawashima, R., Keilholz, S.D., Keliris, G.A., Kelly, C., Kerskens, C., Khokhar, J.Y., Kind, P.C., Langlois, J.B., Lerch, J.P., López-Hidalgo, M.A, Manahan-Vaughan, D., Marchand, F., Mars, R.B., Marsella, G., Micotti, E., Muñoz-Moreno, E., Near, J., Niendorf, T., Otte, W.M., Pais-Roldán, P., Pan, W.J., Prado-Alcalá, R.A., Quirarte, G.L., Rodger, J., Rosenow, T., Sampaio-Baptista, C., Sartorius, A., Sawiak, S.J., Scheenen, T.W.J., Shemesh, N., Shih, Y.Y.I., Shmuel, A., Soria, G., Stoop, R., Thompson, G.J., Till, S.M., Todd, N., Van Der Linden, A., van der Toorn, A., van Tilborg, G.A.F, Vanhove, C., Veltien, A., Verhoye, M., Wachsmuth, L., Weber-Fahr, W., Wenk, P., Yu, X., Zerbi, V., Zhang, N., Zhang, B.B., Zimmer, L., Devenyi, G.A., Chakravarty, M.M. and Hess, A.
Nature Neuroscience 26
(4): 673-681.
April 2023
Proteostasis in T cell aging.
Gressler, A.E., Leng, H., Zinecker, H. and Simon, A.K.
Seminars in Immunology 70
: 101838.
November 2023
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy.
Grosch, M., Schraft, L., Chan, A., Küchenhoff, L., Rapti, K., Ferreira, A.M., Kornienko, J., Li, S., Radke, M.H., Krämer, C., Clauder-Münster, S., Perlas, E., Backs, J., Gotthardt, M., Dieterich, C., van den Hoogenhof, M.M.G., Grimm, D. and Steinmetz, L.M.
Nature Communications 14
(1): 3714.
22 June 2023
Multi-site comparison of parametric T1 and T2 mapping: healthy travelling volunteers in the Berlin research network for cardiovascular magnetic resonance (BER-CMR).
Gröschel, J., Trauzeddel, R.F., Müller, M., von Knobelsdorff-Brenkenhoff, F., Viezzer, D., Hadler, T., Blaszczyk, E., Daud, E. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 25
(1): 47.
14 August 2023
Kardiovaskuläre MRT: akute Myokarditis und myokardiale Mitbeteiligung bei Systemerkrankungen.
Gröschel, J.W., Grassow, L., Bhoyroo, Y. and Schulz-Menger, J.
Kardiologie up2date 19
(3): 269-289.
September 2023
Long COVID and the cardiovascular system - elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint
Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial & Pericardial Diseases.
Gyöngyösi, M., Alcaide, P., Asselbergs, F.W., Brundel, B.J.J.M., Camici, G.G., da Costa Martins, P., Ferdinandy, P., Fontana, M., Girao, H., Gnecchi, M., Gollmann-Tepeköylü, C., Kleinbongard, P., Krieg, T., Madonna, R., Paillard, M., Pantazis, A., Perrino, C., Pesce, M., Schiattarella, G.G., Sluijter, J.P.G., Steffens, S., Tschöpe, C., Van Linthout, S. and Davidson, S.M.
Cardiovascular Research 119
(2): 336-356.
February 2023
Lazy Luna: extendible software for multilevel reader comparison in cardiovascular magnetic resonance imaging.
Hadler, T., Ammann, C., Wetzl, J., Viezzer, D., Gröschel, J., Fenski, M., Abazi, E., Lange, S., Hennemuth, A. and Schulz-Menger, J.
Computer Methods and Programs in Biomedicine 238
: 107615.
August 2023
The effect of brain serotonin deficit (TPH2-KO) on the expression and activity of liver cytochrome P450 enzymes in aging male Dark Agouti rats.
Haduch, A., Bromek, E., Kuban, W., Basińska-Ziobroń, A., Danek, P.J., Alenina, N., Bader, M. and Daniel, W.A.
Pharmacological Reports 75
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Enhanced biosafety of the Sleeping Beauty transposon system by using mRNA as source of transposase to efficiently and stably transfect retinal pigment epithelial cells.
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Biomolecules 13
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7 April 2023
Can single-cell and spatial omics unravel the pathophysiology of pre-eclampsia?
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Journal of Reproductive Immunology 159
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September 2023
Seropositivity of Borrelia burgdorferi s.l. in Germany-an analysis across four German National Cohort (NAKO) study sites.
Hassenstein, M.J., Pischon, T., Karch, A., Peters, A., Kerrinnes, T., Teismann, H., Schneider, A., Thierry, S., Moreno Velásquez, I., Janke, J., Kemmling, Y. and Castell, S.
Scientific Reports 13
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30 November 2023
Analysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort.
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Science Advances 9
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12 May 2023
Ten simple rules for implementing open and reproducible research practices after attending a training course.
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PLoS Computational Biology 19
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5 January 2023
Accelerated simultaneous T2 and T2* mapping of multiple sclerosis lesions using compressed sensing reconstruction of radial RARE-EPI MRI.
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Tomography 9
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31 January 2023
B2 cells contribute to hypertension and natural killer cell activation possibly via AT1-AA in response to placental ischemia.
Herrock, O.T., Deer, E., Amaral, L.M., Campbell, N., Lemon, J., Ingram, N., Cornelius, D.C., Turner, T., Fitzgerald, S., Ibrahim, T., Dechend, R., Wallukat, G. and LaMarca, B.
American Journal of Physiology Renal Physiology 324
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February 2023
Sex-specific stress perfusion cardiac magnetic resonance imaging in suspected ischemic heart disease: insights from SPINS retrospective registry.
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JACC: Cardiovascular Imaging 16
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June 2023
3-dimensional strain analysis of hypertrophic cardiomyopathy: insights from the NHLBI International HCM Registry.
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April 2023
Die Effekte der Herz-Lungen-Maschine auf das intestinale Mikrobiom und die Relation zum postoperativen SIRS [The effects of the cardiopulmonary bypass on the gut microbiome and its contribution to postoperative SIRS].
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G(q)-mediated arrhythmogenic signaling promotes atrial fibrillation.
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Biomedicines 11
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11 February 2023
Radiomics-based aortic flow profile characterization with 4D phase-contrast MRI.
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Genetics-diet crossroads: Unveiling new insights into hypertrophic cardiomyopathy.
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December 2023
Synthetic genetic circuits to uncover the OCT4 trajectories of successful reprogramming of human fibroblasts.
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Monitoring mitochondrial translation by pulse SILAC.
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February 2023
Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice.
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GRaNIE and GRaNPA: inference and evaluation of enhancer-mediated gene regulatory networks.
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Journal of Cerebral Blood Flow and Metabolism 43
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February 2023
Transgenic rat with overproduction of ubiquitous angiotensin-(1-7) presents neuroprotection in a model of ischemia and reperfusion.
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Brain Communications 5
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The effect of renal denervation on T cells in patients with resistant hypertension.
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Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
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Journal of Clinical Investigation 133
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3 April 2023
Indications and management of implantable cardioverter-defibrillator therapy in childhood hypertrophic cardiomyopathy.
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May 2023
Sputum microbiome and chronic obstructive pulmonary disease in a rural Ugandan cohort of well-controlled HIV infection.
Kayongo, A., Bartolomaeus, T.U.P., Birkner, T., Markó, L., Löber, U., Kigozi, E., Atugonza, C., Munana, R., Mawanda, D., Sekibira, R., Uwimaana, E., Alupo, P., Kalyesubula, R., Knauf, F., Siddharthan, T., Bagaya, B.S., Kateete, D.P., Joloba, M.L., Sewankambo, N.K., Jjingo, D., Kirenga, B., Checkley, W. and Forslund, S.K.
Microbiology Spectrum 11
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Frontiers in Immunology 13
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17 January 2023
Spatiotemporal GPCR signaling illuminated by genetically encoded fluorescent biosensors.
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The central role of DNA damage in immunosenescence.
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Frontiers in Aging 4
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3 July 2023
Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies.
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Nature 613
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26 January 2023
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Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
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August 2023
A comprehensive molecular profiling approach reveals metabolic alterations that steer bone tissue regeneration.
Löffler, J., Noom, A., Ellinghaus, A., Dienelt, A., Kempa, S. and Duda, G.N.
Communications Biology 6
(1): 327.
27 March 2023
Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors.
Magenheim, J., Maestro, M.A., Sharon, N., Herrera, P.L., Murtaugh, L.C., Kopp, J., Sander, M., Gu, G., Melton, D.A., Ferrer, J. and Dor, Y.
Cell Stem Cell 30
(4): 488-497.
6 April 2023
Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications.
Malinovska, L., Cappelletti, V., Kohler, D., Piazza, I., Tsai, T.H., Pepelnjak, M., Stalder, P., Dörig, C., Sesterhenn, F., Elsässer, F., Kralickova, L., Beaton, N., Reiter, L., de Souza, N., Vitek, O. and Picotti, P.
Nature Protocols 18
: 659-682.
16 March 2023
Mammalian target of rapamycin inhibition impacts energy homeostasis and induces sex-specific body weight loss in humans.
Mannaa, M., Pfennigwerth, P., Fielitz, J., Gollasch, M. and Boschmann, M.
Journal of Cachexia Sarcopenia and Muscle 14
(6): 2757-2767.
December 2023
New insights from genetic studies of eczema.
Marenholz, I., Arnau-Soler, A., Rosillo-Salazar, O.D. and Lee, Y.A.
Medizinische Genetik 35
(1): 33-45.
5 April 2023
Kinin receptors regulate skeletal muscle regeneration: differential effects for B1 and B2 receptors.
Martins, L., Amorim, W.W., Gregnani, M.F., de Carvalho Araújo, R., Qadri, F., Bader, M. and Pesquero, J.B.
Inflammation Research 72
(8): 1583-1601.
August 2023
Kinins: Locally formed peptides during inflammation with potential use in tissue regeneration.
Martins, L., Bader, M. and Pesquero, J.B.
Inflammation Research 72
(10-11): 1957-1963.
November 2023
Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases: workshop proceedings.
Mastracci, T.L., Apte, M., Amundadottir, L.T., Alvarsson, A., Artandi, S., Bellin, M.D., Bernal-Mizrachi, E., Caicedo, A., Campbell-Thompson, M., Cruz-Monserrate, Z., El Ouaamari, A., Gaulton, K.J., Geisz, A., Goodarzi, M.O., Hara, M., Hull-Meichle, R.L., Kleger, A., Klein, A.P., Kopp, J.L., Kulkarni, R.N., Muzumdar, M.D., Naren, A.P., Oakes, S.A., Olesen, S.S., Phelps, E.A., Powers, A.C., Stabler, C.L., Tirkes, T., Whitcomb, D.C., Yadav, D., Yong, Jing, Zaghloul, N.A., Pandol, S.J. and Sander, M.
Diabetes 72
(4): 433-448.
April 2023
The IgCAM CAR regulates gap junction-mediated coupling on embryonic cardiomyocytes and affects their beating frequency.
Matthaeus, C., Jüttner, R., Gotthardt, M. and Rathjen, F.G.
Life 13
(1): 14.
January 2023
Probing renal oxygenation with T2*-sensitized MRI (BOLD-MRI).
Mendichovszky, I.A., Milani, B., Li, L.P., Niendorf, T., Pruijm, M. and Prasad, P.V.
In:
Advanced clinical MRI of the kidney : methods and protocols.
Springer, Cham, 133-151.
ISBN 978-3-031-40168-8
18 November 2023
Investigating people’s attitudes towards participating in longitudinal health research: an intersectionality-informed perspective.
Merz, S., Jaehn, P., Pischon, T., Fischer, B., Wirkner, K., Rach, S., Guenther, K., Obi, N. and Holmberg, C.
International journal for equity in health 22
(1): 23.
31 January 2023
Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.
Milenkovic, I., Santos Vieira, H.G., Lucas, M.C., Ruiz-Orera, J., Patone, G., Kesteven, S., Wu, J., Feneley, M., Espadas, G., Sabidó, E., Hübner, N., van Heesch, S., Völkers, M. and Novoa, E.M.
Nucleic Acids Research 51
(11): 5301-5324.
23 June 2023
Single-cell transcriptomics for the assessment of cardiac disease.
Miranda, A.M.A., Janbandhu, V., Maatz, H., Kanemaru, K., Cranley, J., Teichmann, S.A., Huebner, N., Schneider, M.D., Harvey, R.P. and Noseda, M.
Nature Reviews Cardiology 20
(5): 289-308.
May 2023
Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis.
Moreno Velásquez, I., Malarstig, A., Baldassarre, D., Borne, Y., de Faire, U., Engström, G., Eriksson, P., Giral, P., Humphries, S.E., Kurl, S., Leander, K., Lind, L., Lindén, A., Orsini, N., Pirro, M., Silveira, A., Smit, A.J., Tremoli, E., Veglia, F., Strawbridge, R.J. and Gigante, B.
Current Research in Translational Medicine 71
(1): 103374.
January 2023
Comment to the article: "Consensus statement on the definition of orthostatic hypertension endorsed by the American Autonomic Society and the Japanese Society of Hypertension" by Jordan and colleagues.
Moreno Velásquez, L. and Pischon, T.
Clinical Autonomic Research 33
(1): 75-76.
February 2023
Early myocardial oedema can predict subsequent cardiomyopathy in high-dose anthracycline therapy.
Muehlberg, F., Kornfeld, M., Zange, L., Ghani, S., Reichardt, A., Reichardt, P. and Schulz-Menger, J.
ESC Heart Failure 10
(1): 616-627.
February 2023
Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development.
Mueller-Calleja, N., Grunz, K., Nguyen, T.S., Posma, J., Pedrosa, D., Meineck, M., Hollerbach, A., Braun, J., Muth, S., Schild, H., Saar, K., Hübner, N., Krishnaswamy, S., Royce, J., Teyton, L., Lemmermann, N.A., Weinmann-Menke, J., Lackner, K.J. and Ruf, W.
Blood 143
(12): 1167-1180.
21 March 2023
Bringing MRI to low- and middle-income countries: Directions, challenges and potential solutions.
Murali, S., Ding, H., Adedeji, F., Qin, C., Obungoloch, J., Asllani, I., Anazodo, U., Ntusi, N.A.B., Mammen, R., Niendorf, T. and Adeleke, S.
NMR in Biomedicine 37
(7): e4992.
July 2023
The Berlin-Buch respiration chamber for energy expenditure measurements.
Mähler, A., Schütte, T., Steiniger, J. and Boschmann, M.
European Journal of Applied Physiology 123
(6): 1359-1368.
June 2023
Salt sensitivity includes effects on immune cell signalling and metabolism.
Müller, D.N., Geisberger, S., Kleinewietfeld, M. and Jantsch, J.
Nature Reviews Immunology 23
(6): 341-342.
June 2023
Autoantibodies against the chemokine receptor 3 predict cardiovascular risk.
Müller, F.S., Aherrahrou, Z., Grasshoff, H., Heidorn, M.W., Humrich, J.Y., Johanson, L., Aherrahrou, R., Reinberger, T., Schulz, A., Ten Cate, V., Robles, A.P., Koeck, T., Rapp, S., Lange, T., Brachaczek, L., Luebber, F., Erdmann, J., Heidecke, H., Schulze-Forster, K., Dechend, R., Lackner, K.J., Pfeiffer, N., Ghaemi Kerahrodi, J., Tüscher, O., Schwarting, A., Strauch, K., Münzel, T., Prochaska, J.H., Riemekasten, G. and Wild, P.S.
European Heart Journal 44
(47): 4935-4949.
14 December 2023
A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A., Bakina, O., Badillo Lisakowski, V., Olivares-Chauvet, P., Conrad, T., Gotthardt, M., Kettenmann, H. and Junker, J.P.
Molecular Systems Biology 19
(2): e11147.
10 February 2023
Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer.
Nimptsch, K., Aleksandrova, K., Pham, T.T., Papadimitriou, N., Janke, J., Christakoudi, S., Heath, A., Olsen, A., Tjønneland, A., Schulze, M.B., Katzke, V., Kaaks, R., van Guelpen, B., Harbs, J., Palli, D., Macciotta, A., Pasanisi, F., Colorado Yohar, S.M., Guevara, M., Amiano, P., Grioni, S., Jakszyn, P.G., Figueiredo, J.C., Samadder, N.J., Li, C.I., Moreno, V., Potter, J.D., Schoen, R.E., Um, C.Y., Weiderpass, E., Jenab, M., Gunter, M.J. and Pischon, T.
BMC Medicine 21
(1): 391.
13 October 2023
Maternal COVID-19 causing intrauterine foetal demise with microthrombotic placental insufficiency: a case report.
Nonn, O., Bonstingl, L., Sallinger, K., Neuper, L., Fuchs, J., Gauster, M., Huppertz, B., Brislinger, D., El-Heliebi, A., Fluhr, H., Kampelmühler, E. and Klaritsch, P.
BMC Pregnancy and Childbirth 23
(1): 653.
9 September 2023
The effect of probiotic and synbiotic supplementation on appetite-regulating hormones and desire to eat: a systematic review and meta-analysis of clinical trials.
Noormohammadi, M., Ghorbani, Z., Löber, U., Mahdavi-Roshan, M., Bartolomaeus, T.U.P., Kazemi, A., Shoaibinobarian, N. and Forslund, S.K.
Pharmacological Research 187
: 106614.
January 2023
Disease- and sex-specific differences in patients with heart valve disease: a proteome study.
Nordmeyer, S., Kraus, M., Ziehm, M., Kirchner, M., Schafstedde, M., Kelm, M., Niquet, S., Stephen, M.M., Baczko, I., Knosalla, C., Schapranow, M.P., Dittmar, G., Gotthardt, M., Falcke, M., Regitz-Zagrosek, V., Kuehne, T. and Mertins, P.
Life Science Alliance 6
(3): e202201411.
March 2023
Radiofrequency antenna concepts for human cardiac MR at 14.0 T.
Nurzed, B., Kuehne, A., Aigner, C.S., Schmitter, S., Niendorf, T. and Eigentler, T.W.
Magnetic Resonance Materials in Physics Biology and Medicine 36
(2): 257-277.
April 2023
Daratumumab for the treatment of refractory ANCA-associated vasculitis.
Ostendorf, L., Burns, M., Wagner, D.L., Enghard, P., Amann, K., Mei, H., Eckardt, K.U., Seelow, E. and Schreiber, A.
RMD Open 9
(1): e002742.
10 January 2023
Roles of cholesterol and PtdIns(4,5)P(2) in the regulation of STIM1-Orai1 channel function.
Pacheco, J., Bohórquez-Hernández, A., Méndez-Acevedo, K.M., Sampieri, A. and Vaca, L.
Advances in Experimental Medicine and Biology 1422
: 305-326.
2023
Maternal haemodynamics in Hypertensive Disorders of Pregnancy under antihypertensive therapy (HyperDiP): study protocol for a prospective observational case-control study.
Palmrich, P., Haase, N., Sugulle, M., Kalafat, E., Khalil, A. and Binder, J.
BMJ Open 13
(6): e065444.
June 2023
Gut microbiome and atrial fibrillation - results from a large population-based study.
Palmu, J., Börschel, C.S., Ortega-Alonso, A., Markó, L., Inouye, M., Jousilahti, P., Salido, R.A., Sanders, K., Brennan, C., Humphrey, G.C., Sanders, J.G., Gutmann, F., Linz, D., Salomaa, V., Havulinna, A.S., Forslund, S.K., Knight, R., Lahti, L., Niiranen, T. and Schnabel, R.B.
EBioMedicine 91
: 104583.
May 2023
Galectin-3 interacts with PD-1 and counteracts the PD-1 pathway-driven regulation of T cell and osteoclast activity in Rheumatoid Arthritis.
Pedersen, K., Nielsen, M.A., Juul-Madsen, K., Hvid, M., Deleuran, B. and Greisen, S.R.
Scandinavian Journal of Immunology 97
(2): e13245.
February 2023
Functional assay for assessment of agonistic or antagonistic activity of angiotensin AT(2) receptor ligands reveals that EMA401 and PD123319 have agonistic properties.
Peluso, A.A., Souza Silva, I.M., Villela, D.C., Hansen, P.B.L., Hallberg, A., Bader, M., Santos, R., Sumners, C. and Muscha Steckelings, U.
Biochemical Pharmacology 216
: 115793.
October 2023
Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Petrović, S., Roske, Y., Rami, B., Phan, M.H.Q., Panakova, D. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 120
(4): e2208941120.
24 January 2023
SLC26A1 is a major determinant of sulfate homeostasis in humans.
Pfau, A., López-Cayuqueo, K.I., Scherer, N., Wuttke, M., Wernstedt, A., González Fassrainer, D., Smith, D.E., van de Kamp, J.M., Ziegeler, K., Eckardt, K.U., Luft, F.C., Aronson, P.S., Köttgen, A., Jentsch, T.J. and Knauf, F.
Journal of Clinical Investigation 133
(3): e161849.
1 February 2023
Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study.
Pham, T.T., Nimptsch, K., Papadimitriou, N., Aleksandrova, K., Jenab, M., Gunter, M.J., Le Marchand, L., Li, L., Lynch, B.M., Castellví-Bel, S., Phipps, A.I., Schmit, S.L., Brenner, H., Ogino, S., Giovannucci, E. and Pischon, T.
Journal of Cancer Research and Clinical Oncology 149
(16): 14889-14900.
November 2023
Autophagy orchestrates the crosstalk between cells and organs.
Piletic, K., Alsaleh, G. and Simon, A.K.
EMBO Reports 24
(9): e57289.
6 September 2023
Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease.
Piwecka, M., Rajewsky, N. and Rybak-Wolf, A.
Nature Reviews Neurology 19
(6): 346-362.
June 2023
What can Ribo-seq, immunopeptidomics, and proteomics tell us about the non-canonical proteome?
Prensner, J.R., Abelin, J.G., Kok, L.W., Clauser, K.R., Mudge, J.M., Ruiz-Orera, J., Bassani-Sternberg, M., Moritz, R.L., Deutsch, E.W. and van Heesch, S.
Molecular & Cellular Proteomics 22
(9): 100631.
September 2023
Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.
Proft, S., Leiz, J., Heinemann, U., Seelow, D., Schmidt-Ott, K.M. and Rutkiewicz, M.
BMC Genomics 24
(1): 736.
4 December 2023
Cryo-EM captures early ribosome assembly in action.
Qin, B., Lauer, S.M., Balke, A., Vieira-Vieira, C.H., Bürger, J., Mielke, T., Selbach, M., Scheerer, P., Spahn, C.M.T. and Nikolay, R.
Nature Communications 14
(1): 898.
17 February 2023
Retrotransposon: a versatile player in human preimplantation development and health.
Qu, Y., Izsvák, Z. and Wang, J.
Life Medicine 2
(1): 1-3.
February 2023
LINC01013 is a determinant of fibroblast activation and encodes a novel fibroblast-activating micropeptide.
Quaife, N.M., Chothani, S., Schulz, J.F., Lindberg, E.L., Vanezis, K., Adami, E., O'Fee, K., Greiner, J., Litviňuková, M., van Heesch, S., Whiffin, N., Hubner, N., Schafer, S., Rackham, O., Cook, S.A. and Barton, P.J.R.
Journal of cardiovascular translational research 16
(1): 77-85.
February 2023
An integrate-and-fire approach to Ca(2+) signaling. Part II: Cumulative refractoriness.
Ramlow, L., Falcke, M. and Lindner, B.
Biophysical Journal 122
(24): 4710-4729.
19 December 2023
An integrate-and-fire approach to Ca(2+) signaling. Part I: Renewal model.
Ramlow, L., Falcke, M. and Lindner, B.
Biophysical Journal 122
(4): 713-736.
21 February 2023
Protein intake and risk of urolithiasis and kidney diseases: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society.
Remer, T., Kalotai, N., Amini, A.M., Lehmann, A., Schmidt, A., Bischoff-Ferrari, H.A., Egert, S., Ellinger, S., Kroke, A., Kühn, T., Lorkowski, S., Nimptsch, K., Schwingshackl, L., Zittermann, A., Watzl, B. and Siener, R.
European Journal of Nutrition 62
(5): 1957-1975.
August 2023
Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Richter, F.C., Friedrich, M., Kampschulte, N., Piletic, K., Alsaleh, G., Zummach, R., Hecker, J., Pohin, M., Ilott, N., Guschina, I., Wideman, S.K., Johnson, E., Borsa, M., Hahn, P., Morriseau, C., Hammock, B.D., Schipper, H.S., Edwards, C.M, Zechner, R., Siegmund, B., Weidinger, C., Schebb, N.H., Powrie, F. and Simon, A.K.
EMBO Journal 42
(6): e112202.
15 March 2023
Comments on the myPACE randomized clinical trial.
Rodolico, D. and Schiattarella, G.G.
JAMA Cardiology 8
(8): 794-795.
August 2023
The lure of cardiac metabolism in the diagnosis, prevention, and treatment of heart failure.
Rodolico, D., Schiattarella, G.G. and Taegtmeyer, H.
JACC: Heart Failure 11
(6): 637-645.
June 2023
The contribution of the AT1 receptor to erythropoiesis.
Rodrigues, A.F. and Bader, M.
Biochemical Pharmacology 217
: 115805.
November 2023
Angiotensin deficient FVB/N mice are normotensive.
Rodrigues, A.F., Todiras, M., Qadri, F., Alenina, N. and Bader, M.
British Journal of Pharmacology 180
(14): 1843-1861.
July 2023
Update Curriculum Kardiale Magnetresonanztomographie [Update on the cardiac magnetic resonance imaging curriculum].
Rolf, A., Eitel, I., Neizel-Wittke, M., Radunski, U.K., Bernhardt, P., von Knobelsdorff, F., André, F., Nagel, E., Schulz-Menger, J. and Kelle, S.
Kardiologie 17
(3): 173-185.
June 2023
The potential of cross-linking mass spectrometry in the development of protein-protein interaction modulators.
Ruwolt, M., Piazza, I. and Liu, F.
Current Opinion in Structural Biology 82
: 102648.
October 2023
Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.
Rybak-Wolf, A., Wyler, E., Pentimalli, T.M., Legnini, I., Oliveras Martinez, A., Glažar, P., Loewa, A., Kim, S.J., Kaufer, B.B., Woehler, A., Landthaler, M. and Rajewsky, N.
Nature Microbiology 8
(7): 1252-1266.
July 2023
Advanced radio frequency applicators for thermal magnetic resonance theranostics of brain tumors.
Saha, N., Kuehne, A., Millward, J.M., Eigentler, T.W., Starke, L., Waiczies, S. and Niendorf, T.
Cancers 15
(8): 2303.
14 April 2023
High fidelity 3D magnetic stray field mapping of smartphones to address safety considerations with active implantable electronic medical devices.
Saha, N., Millward, J.M., Herrmann, C.J.J., Rahimi, F., Han, H., Lacour, P., Blaschke, F. and Niendorf, T.
Sensors 23
(3): 1209.
20 January 2023
VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats.
Samuelsson, A.M., Bartolomaeus, T.U.P., Anandakumar, H., Thowsen, I., Nikpey, E., Han, J., Marko, L., Finne, K., Tenstad, O., Eckstein, J., Berndt, N., Kühne, T., Kedziora, S., Sultan, I., Skogstrand, T., Karlsen, T.V., Nurmi, H., Forslund, S.K., Bollano, E., Alitalo, K., Muller, D.N. and Wiig, H.
Cardiovascular Research 119
(7): 1553-1567.
4 July 2023
Transgenic angiotensin-converting enzyme 2 overexpression in the rat vasculature protects kidneys from ageing-induced injury.
Sanad, A.M., Qadri, F., Popova, E., Rodrigues, A.F., Heinbokel, T., Quach, S., Schulz, A., Bachmann, S., Kreutz, R., Alenina, N. and Bader, M.
Kidney International 104
(2): 293-304.
August 2023
Gene editing to improve pancreatic beta cell yield in directed differentiation of human pluripotent stem cells.
The regents of the university of California.
WO-2023137235-A3.
20 July 2023
Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.
Sandmann, C.L., Schulz, J.F., Ruiz-Orera, J., Kirchner, M., Ziehm, M., Adami, E., Marczenke, M., Christ, A., Liebe, N., Greiner, J., Schoenenberger, A., Mücke, M.B., Liang, N., Moritz, R.L., Sun, Z., Deutsch, E.W., Gotthardt, M., Mudge, J.M., Prensner, J.R., Willnow, T.E., Mertins, P., van Heesch, S. and Hubner, N.
Molecular Cell 83
(6): 994-1011.e18.
16 March 2023
Curvature in biological systems: its quantification, emergence and implications across the scales.
Schamberger, B., Roschger, A., Ziege, R., Anselme, K., Amar, M.B., Bykowski, M., Castro, A.P.G., Cipitria, A., Coles, R., Dimova, R., Eder, M., Ehrig, S., Escudero, L.M., Evans, M.E., Fernandes, P.R., Fratzl, P., Geris, L., Gierlinger, N., Hannezo, E., Iglič, A., Kirkensgaard, J.J.K., Kollmannsberger, P., Kowalewska, Ł., Kurniawan, N.A., Papantoniou, I., Pieuchot, L., Pires, T.H.V., Renner, L., Sageman-Furnas, A., Schröder-Turk, G.E., Sengupta, A., Sharma, V.R., Tagua, A., Tomba, C., Trepat, X., Waters, S.L., Yeo, E., Bidan, C.M. and Dunlop, J.W.C.
Advanced Materials 35
(13): e2206110.
15 March 2023
Induction of kidney-related gene programs through co-option of SALL1 in mole ovotestes.
Schindler, M., Osterwalder, M., Harabula, I., Wittler, L., Tzika, A.C., Dechmann, D.K.N., Vingron, M., Visel, A., Haas, S. and Real, F.M.
Development 150
(17): dev201562.
1 September 2023
Scaling the mountains: what lies above 7 Tesla magnetic resonance?
Schmidt, R., Keban, E., Bollmann, S., Wiggins, C.J. and Niendorf, T.
Magnetic Resonance Materials in Physics Biology and Medicine 36
(2): 151-157.
April 2023
The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis.
Schoeler, M., Ellero-Simatos, S., Birkner, T., Mayneris-Perxachs, J., Olsson, L., Brolin, H., Löber, U., Kraft, J.D., Polizzi, A., Martí-Navas, M., Puig, J., Moschetta, A., Montagner, A., Gourdy, P., Heymes, C., Guillou, H., Tremaroli, V., Fernández-Real, J.M., Forslund, S.K., Burcelin, R. and Caesar, R.
Nature Communications 14
(1): 5329.
1 September 2023
Gendiagnostik bei kardiovaskulären Erkrankungen.
Schulze-Bahr, E., Klaassen, S., Gerull, B., von Kodolitsch, Y., Landmesser, U., Rieß, O., Meder, B. and Schunkert, H.
Kardiologie 17
: 300-349.
September 2023
Automated image quality assessment for selecting among multiple magnetic resonance image acquisitions in the German National Cohort study.
Schuppert, C., Rospleszcz, S., Hirsch, J.G., Hoinkiss, D.C., Köhn, A., von Krüchten, R., Russe, M.F., Keil, T., Krist, L., Schmidt, B., Michels, K.B., Schipf, S., Brenner, H., Kröncke, T.J., Pischon, T., Niendorf, T., Schulz-Menger, J., Forsting, M., Völzke, H., Hosten, N., Bülow, R., Zaitsev, M., Kauczor, H.U., Bamberg, F., Günther, M. and Schlett, C.L.
Scientific Reports 13
(1): 22745.
20 December 2023
Chronic disease outcome metadata from German observational studies – public availability and FAIR principles.
Schwedhelm, C., Nimptsch, K., Ahrens, W., Hasselhorn, H.M., Jöckel, K.H., Katzke, V., Kluttig, A., Linkohr, B., Mikolajczyk, R., Nöthlings, U., Perrar, I., Peters, A., Schmidt, C.O., Schmidt, B., Schulze, M.B., Stang, A., Zeeb, H. and Pischon, T.
Scientific Data 10
: 868.
5 December 2023
Short and long-term photostability of 3D printed fluorescent phantoms for near-infrared diffuse optical imaging.
Schädel-Ebner, Sandra, Hirsch, Ole, Gladytz, T., Gutkelch, Dirk, Licha, Kai, Berger, Jörn and Grosenick, Dirk
In: European Conferences on Biomedical Optics 2017, 25-29 June 2023, Munich, Germany.
9 August 2023
Myocarditis and sports in the young: data from a nationwide registry on myocarditis - "MYKKE-Sport".
Schöffl, I., Holler, S., Dittrich, S., Pickardt, T., Opgen-Rhein, B., Boehne, M., Wannenmacher, B., Reineke, K., Wiegand, G., Hecht, T., Kaestner, M., Messroghli, D., Schubert, S., Seidel, F. and Weigelt, A.
Frontiers in Sports and Active Living 5
: 1197640.
26 June 2023
A circular RNA expressed from the FAT3 locus regulates neural development.
Seeler, S., Andersen, M.S., Sztanka-Toth, T., Rybiczka-Tešulov, M., van den Munkhof, M.H., Chang, C.C., Maimaitili, M., Venø, M.T., Hansen, T.B., Pasterkamp, R.J., Rybak-Wolf, A., Denham, M., Rajewsky, N., Kristensen, L.S. and Kjems, J.
Molecular Neurobiology 60
(6): 3239–3260.
June 2023
Potentiating tweezer affinity to a protein interface with sequence-defined macromolecules on nanoparticles.
Seiler, T., Lennartz, A., Klein, K., Hommel, K., Figueroa Bietti, A., Hadrovic, I., Kollenda, S., Sager, J., Beuck, C., Chlosta, E., Bayer, P., Juul-Madsen, K., Vorup-Jensen, T., Schrader, T., Epple, M., Knauer, S.K. and Hartmann, L.
Biomacromolecules 24
(8): 3666-3679.
14 August 2023
Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A., Walter, S., Markó, L., McMurray, B.J., Sunaga-Franze, D.Y., Xu, M., Zühlke, K., Russwurm, M., Bartolomaeus, T.U.P., Langanki, R., Qadri, F., Heuser, A., Patzak, A., Forslund, S.K., Bähring, S., Borodina, T., Persson, P.B., Maass, P.G., Bader, M. and Klussmann, E.
Kidney International 104
(2): 388-393.
August 2023
Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury.
Sieckmann, T., Schley, G., Ögel, N., Kelterborn, S., Boivin, F.J., Fähling, M., Ashraf, M.I., Reichel, M., Vigolo, E., Hartner, A., Lichtenberger, F.B., Breiderhoff, T., Knauf, F., Rosenberger, C., Aigner, F., Schmidt-Ott, K., Scholz, H. and Kirschner, K.M.
Kidney International 104
(1): 90-107.
July 2023
Women physicians in cardiovascular magnetic resonance: past, present, and future.
Sierra-Galan, L.M., Aggarwal, N.R., Stojanovska, J., Raman, S.V., Han, Y., Ferreira, V.M., Thomas, K., Seiberlich, N., Parwani, P., Bucciarelli-Ducci, C., Baldassarre, L.A., Mavrogeni, S., Ordovas, K., Schulz-Menger, J. and Bandettini, W.P.
Frontiers in Cardiovascular Medicine 9
: 984326.
4 January 2023
Worldwide variation in cardiovascular magnetic resonance practice models.
Sierra-Galan, L.M., Estrada-Lopez, E.E.S., Ferrari, V.A., Raman, S.V., Ferreira, V.M., Raj, V., Joseph, E., Schulz-Menger, J., Chan, C.W.S., Chen, S.S.M., Cheng, Y., De Lara Fernandez, J., Terashima, M. and Albert, T.S.E.
Journal of Cardiovascular Magnetic Resonance 25
(1): 38.
3 July 2023
Tryptophan hydroxylase-2-mediated serotonin biosynthesis suppresses cell reprogramming into pluripotent state.
Sinenko, S.A., Kuzmin, A.A., Skvortsova, E.V., Ponomartsev, S.V., Efimova, E.V., Bader, M., Alenina, N. and Tomilin, A.N.
International Journal of Molecular Sciences 24
(5): 4862.
2 March 2023
A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass.
Singh, M., Kondrashkina, A., Widmann, T.J., Cortes, J.L., Bansal, V., Wang, J., Römer, C., Garcia-Canadas, M., Garcia-Perez, J.L., Hurst, L.D. and Izsvak, Z.
PLoS Biology 21
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20 June 2023
Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH.
Singh, M., Kondraskhina, A.M., Hurst, L.D. and Izsvák, Z.
Journal of Clinical Investigation 133
(14): e172278.
17 July 2023
Impaired T cell IRE1α-XBP1 signaling directs inflammation in experimental Heart Failure with Preserved Ejection Fraction.
Smolgovsky, S., Bayer, A.L., Kaur, K., Sanders, E., Aronovitz, M., Filipp, M.E., Thorp, E.B., Schiattarella, G.G., Hill, J.A., Blanton, R.M., Cubillos-Ruiz, J.R. and Alcaide, P.
Journal of Clinical Investigation 133
(24): e171874.
15 December 2023
Urinary T cells identify renal antineutrophil cytoplasmic antibody-associated vasculitis and predict prognosis: a proof of concept study.
Sonnemann, J., Klocke, J., Bieringer, M., Rousselle, A., Eckardt, K.U., Elitok, S., Popovic, S., Bachmann, S., Kettritz, R., Salama, A.D., Enghard, P. and Schreiber, A.
Kidney International Reports 8
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April 2023
Structure-based design of xanthine-imidazopyridines and -imidazothiazoles as highly potent and in vivo efficacious tryptophan hydroxylase inhibitors.
Specker, E., Wesolowski, R., Schütz, A., Matthes, S., Mallow, K., Wasinska-Kalwa, M., Winkler, L., Oder, A., Alenina, N., Pleimes, D., von Kries, J.P., Heinemann, U., Bader, M. and Nazaré, M.
Journal of Medicinal Chemistry 66
(21): 14866-14896.
9 November 2023
BLN protein induces cardiac hypertrophy and failure.
Sperling, S.R.
Nature Cardiovascular Research 2
(11): 964-965.
November 2023
Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation.
Sporre, E., Karlsen, J., Schriever, K., Asplund-Samuelsson, J., Janasch, M., Strandberg, L., Karlsson, A., Kotol, D., Zeckey, L., Piazza, I., Syrén, P.O., Edfors, F. and Hudson, E.P.
Communications Biology 6
(1): 947.
18 September 2023
Thrifty energy phenotype predicts weight regain in postmenopausal women with overweight or obesity and is related to FGFR1 signaling.
Spranger, L., Weiner, J., Bredow, J., Zeitz, U., Grittner, U., Boschmann, M., Dickmann, S., Stobäus, N., Schwartzenberg, R.J., Brachs, M., Spranger, J. and Mai, K.
Clinical Nutrition 42
(4): 559-567.
April 2023
First in vivo fluorine-19 magnetic resonance imaging of the multiple sclerosis drug siponimod.
Starke, L., Millward, J.M., Prinz, C., Sherazi, F., Waiczies, H., Lippert, C., Nazaré, M., Paul, F., Niendorf, T. and Waiczies, S.
Theranostics 13
(4): 1217-1234.
5 February 2023
The interplay of family history of depression and early trauma: associations with lifetime and current depression in the German national cohort (NAKO).
Streit, F., Völker, M.P., Klinger-König, J., Zillich, L., Frank, J., Reinhard, I., Foo, J.C., Witt, S.H., Sirignano, L., Becher, H., Obi, N., Riedel, O., Do, S., Castell, S., Hassenstein, M.J., Karch, A., Stang, A., Schmidt, B., Schikowski, T., Stahl-Pehe, A., Brenner, H., Perna, L., Greiser, K.H., Kaaks, R., Michels, K.B., Franzke, C.W., Peters, A., Fischer, B., Konzok, J., Mikolajczyk, R., Führer, A., Keil, T., Fricke, J., Willich, S.N., Pischon, T., Völzke, H., Meinke-Franze, C., Loeffler, M., Wirkner, K., Berger, K., Grabe, H.J. and Rietschel, M.
Frontiers in Epidemiology 3
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23 May 2023
Integrated proteomics unveils nuclear PDE3A2 as a regulator of cardiac myocyte hypertrophy.
Subramaniam, G., Schleicher, K., Kovanich, D., Zerio, A., Folkmanaite, M., Chao, Y.C., Surdo, N.C., Koschinski, A., Hu, J., Scholten, A., Heck, A.J.R, Ercu, M., Sholokh, A., Chan Park, K., Klussmann, E., Meraviglia, V., Bellin, M., Zanivan, S., Hester, S., Mohammed, S. and Zaccolo, M.
Circulation Research 132
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31 March 2023
Long-read sequencing reveals extensive DNA methylations in human gut phagenome contributed by prevalently phage-encoded methyltransferases.
Sun, C., Chen, J., Jin, M., Zhao, X., Li, Y., Dong, Y., Gao, N., Liu, Z., Bork, P., Zhao, X.M. and Chen, W.H.
Advanced Science 10
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5 September 2023
Angiotensin-(1-7) mediated calcium signalling by MAS.
Sureshkumar, P., Souza dos Santos, R.A., Alenina, N., Mergler, S. and Bader, M.
Peptides 165
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July 2023
Risk of pre-term birth as a function of sleep quality and obesity: prospective analysis in a large Prematurity Research Cohort.
Sutcliffe, S., Zhao, P., Pilz, L.K., Oakes, M., Frolova, A.I., Herzog, E.D. and England, S.K.
Sleep Advances 4
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13 November 2023
Diastolische Dysfunktion und HFpEF bei CKD: Ein Update [Diastolic dysfunction and HFpEF in CKD: An update].
Szijártó, I.A. and Wilck, N.
Nephrologie 18
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November 2023
The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest.
Szklarczyk, D., Kirsch, R., Koutrouli, M., Nastou, K., Mehryary, F., Hachilif, R., Gable, A.L., Fang, T., Doncheva, N.T., Pyysalo, S., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 51
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6 January 2023
Insm1 regulates mTEC development and immune tolerance.
Tao, W., Ye, Z., Wei, Y., Wang, J., Yang, W., Yu, G., Xiong, J. and Jia, S.
Cellular and Molecular Immunology 20
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December 2023
Genome architecture mapping detects transcriptionally active, multiway chromatin contacts.
Thieme, C.J. and Pombo, A.
Nature Methods 20
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July 2023
The gut microbiota in multiple sclerosis varies with disease activity.
Thirion, F., Sellebjerg, F., Fan, Y., Lyu, L., Hansen, T.H., Pons, N., Levenez, F., Quinquis, B., Stankevic, E., Søndergaard, H.B., Dantoft, T.M., Poulsen, C.S., Forslund, S.K., Vestergaard, H., Hansen, T., Brix, S., Oturai, A., Sørensen, P.S., Ehrlich, S.D. and Pedersen, O.
Genome Medicine 15
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5 January 2023
Alteration of gut microbiome in patients with schizophrenia indicates links between bacterial tyrosine biosynthesis and cognitive dysfunction.
Thirion, F., Speyer, H., Hansen, T.H., Nielsen, T., Fan, Y., Le Chatelier, E., Fromentin, S., Berland, M., Oñate, F.P., Pons, N., Galleron, N., Levenez, F., Markó, L., Birkner, T., Jørgensen, T., Forslund, S.K., Vestergaard, H., Hansen, T., Nordentoft, M., Mors, O., Benros, M.E., Pedersen, O. and Ehrlich, S.D.
Biological Psychiatry Global Open Science 3
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April 2023
Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.
Urizar, A.I., Prause, M., Ingerslev, L.R., Wortham, M., Sui, Y., Sander, M., Williams, K., Barrès, R., Larsen, M.R., Christensen, G.L. and Billestrup, N.
Cell Death & Disease 14
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5 July 2023
G-protein-coupled receptor MAS DeLETION produces a preeclampsia-like phenotype in FVB/N mice.
Vieira Pimentel, R.L., Braga, J.F., Velloso, E.P.P., Lautner, R.Q., Oliveira, M.L., Todiras, M., Alenina, N., Bader, M., de Sousa, F.G., Beier, S.L. and Souza Dos Santos, R.A.
Clinical Science 137
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August 2023
Introduction of a cascaded segmentation pipeline for parametric T1 mapping in cardiovascular magnetic resonance to improve segmentation performance.
Viezzer, D., Hadler, T., Ammann, C., Blaszczyk, E., Fenski, M., Grandy, T.H., Wetzl, J., Lange, S. and Schulz-Menger, J.
Scientific Reports 13
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6 February 2023
Associations of accelerometer-based sedentary bouts with adiposity markers among German adults - results from a cross-sectional study.
Voigt, L., Ullrich, A., Groß, S., Guertler, D., Jaeschke, L., Dörr, M., van den Berg, N., John, U. and Ulbricht, S.
BMC Public Health 23
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10 March 2023
Associations of migration, socioeconomic position and social relations with depressive symptoms – analyses of the German National Cohort baseline data.
Vonneilich, N., Becher, H., Bohn, B., Brandes, B., Castell, S., Deckert, A., Dragano, N., Franzke, C.W., Führer, A., Gastell, S., Greiser, H., Keil, T., Klett-Tammen, C., Koch-Gallenkamp, L., Krist, L., Leitzmann, M., Meinke-Franze, C., Mikolajczyk, R., Moreno Velasquez, I., Obi, N., Peters, A., Pischon, T., Reuter, M., Schikowski, T., Schmidt, B., Schulze, M., Sergeev, D., Stang, A., Völzke, H., Wiessner, C., Zeeb, H., Lüdecke, D. and von dem Knesebeck, O.
International Journal of Public Health 68
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18 July 2023
Impact of first-line use of caplacizumab on treatment outcomes in immune thrombotic thrombocytopenic purpura.
Völker, L.A., Kaufeld, J., Balduin, G., Merkel, L., Kühne, L., Eichenauer, D.A., Osterholt, T., Hägele, H., Kann, M., Grundmann, F., Kolbrink, B., Schulte, K., Gäckler, A., Kribben, A., Boss, K., Potthoff, S.A., Rump, L.C., Schmidt, T., Mühlfeld, A.S., Schulmann, K., Hermann, M., Gaedeke, J., Sauerland, K., Bramstedt, J., Hinkel, U.P., Miesbach, W., Bauer, F., Westhoff, T.H., Bruck, H., Buxhofer-Ausch, V., Müller, T.J., Wendt, R., Harth, A., Schreiber, A., Seelow, E., Tölle, M., Gohlisch, C., Bieringer, M., Geuther, G., Jabs, W.J., Fischereder, M., von Bergwelt-Baildon, A., Schönermarck, U., Knoebl, P., Menne, J. and Brinkkoetter, P.T.
Journal of Thrombosis and Haemostasis 21
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March 2023
Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.
Wang, G., Chiou, J., Zeng, C., Miller, M., Matta, I., Han, J.Y., Kadakia, N., Okino, M.L., Beebe, E., Mallick, M., Camunas-Soler, J., Dos Santos, T., Dai, X.Q., Ellis, C., Hang, Y., Kim, S.K., MacDonald, P.E., Kandeel, F.R., Preissl, S., Gaulton, K.J. and Sander, M.
Nature Genetics 55
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June 2023
Protocol of the Berlin Long-term Observation of Vascular Events (BeLOVE): a prospective cohort study with deep phenotyping and long-term follow up of cardiovascular high-risk patients.
Weber, J.E., Ahmadi, M., Boldt, L.H., Eckardt, K.U., Edelmann, F., Gerhardt, H., Grittner, U., Haubold, K., Hübner, N., Kollmus-Heege, J., Landmesser, U., Leistner, D.M., Mai, K., Müller, D.N., Nolte, C.H., Pieske, B., Piper, S.K., Rattan, S., Rauch, G., Schmidt, S., Schmidt-Ott, K.M., Schönrath, K., Schulz-Menger, J., Schweizerhof, O., Siegerink, B., Spranger, J., Ramachandran, V.S., Witzenrath, M., Endres, M. and Pischon, T.
BMJ Open 13
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31 October 2023
Competency-based cardiac imaging for patient-centred care. A statement of the European Society of Cardiology (ESC). With the contribution of the European Association of Cardiovascular Imaging (EACVI), and the support of the Association of Cardiovascular Nursing & Allied Professions (ACNAP), the Association for Acute CardioVascular Care (ACVC), the European Association of Preventive Cardiology (EAPC), the European Association of Percutaneous Cardiovascular Interventions (EAPCI), the European Heart Rhythm Association (EHRA), and the Heart Failure Association (HFA) of the ESC.
Westwood, M., Almeida, A.G., Barbato, E., Delgado, V., Dellegrottaglie, S., Fox, K.F., Gargani, L., Huber, K., Maurovich-Horvat, P., Merino, J.L., Mindham, R., Muraru, D., Neubeck, L., Nijveldt, R., Papadakis, M., Pontone, G., Price, S., Rosano, G.M.C., Rossi, A., Sade, L.E., Schulz-Menger, J., Weidinger, F., Achenbach, S. and Petersen, S.E.
European Heart Journal - Imaging Methods and Practice 1
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September 2023
Competency-based cardiac imaging for patient-centred care. A statement of the European Society of Cardiology (ESC).
Westwood, M., Almeida, A.G., Barbato, E., Delgado, V., Dellegrottaglie, S., Fox, K.F., Gargani, L., Huber, K., Maurovich-Horvat, P., Merino, J.L., Mindham, R., Muraru, D., Neubeck, L., Nijveldt, R., Papadakis, M., Pontone, G., Price, S., Rosano, G.M.C., Rossi, A., Sade, L.E., Schulz-Menger, J., Weidinger, F., Achenbach, S. and Petersen, S.E.
European Heart Journal 44
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1 December 2023
Competency-based cardiac imaging for patient-centred care. A statement of the European Society of Cardiology (ESC).
Westwood, M., Almeida, A.G., Barbato, E., Delgado, V., Dellegrottaglie, S., Fox, K.F., Gargani, L., Huber, K., Maurovich-Horvat, P., Merino, J.L., Mindham, R., Muraru, D., Neubeck, L., Nijveldt, R., Papadakis, M., Pontone, G., Price, S., Rosano, G.M.C., Rossi, A., Sade, L.E., Schulz-Menger, J., Weidinger, F., Achenbach, S. and Petersen, S.E.
European Heart Journal - Cardiovascular Imaging 24
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November 2023
Changes of aortic hemodynamics after aortic valve replacement - a four dimensional flow cardiovascular magnetic resonance follow up study.
Wiesemann, S., Trauzeddel, R.F., Musa, A., Hickstein, R., Mayr, T., von Knobelsdorff-Brenkenhoff, F., Bollache, E., Markl, M. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 10
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14 February 2023
Nutrient regulation of the islet epigenome controls adaptive insulin secretion.
Wortham, M., Liu, F., Harrington, A.R., Fleischman, J.Y., Wallace, M., Mulas, F., Mallick, M., Vinckier, N.K., Cross, B.R., Chiou, J., Patel, N.A., Sui, Y., McGrail, C., Jun, Y., Wang, G., Jhala, U.S., Schüle, R., Shirihai, O.S., Huising, M.O., Gaulton, K.J., Metallo, C.M. and Sander, M.
Journal of Clinical Investigation 133
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17 April 2023
Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine.
Wu, F., Li, X., Looso, M., Liu, H., Ding, D., Günther, S., Kuenne, C., Liu, S., Weissmann, N., Boettger, T., Atzberger, A., Kolahian, S., Renz, H., Offermanns, S., Gärtner, U., Potente, M., Zhou, Y., Yuan, X. and Braun, T.
Nature Genetics 55
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January 2023
Human gut microbiome researches over the last decade: current challenges and future directions.
Wu, H., Forslund, S., Wang, Z. and Zhao, G.
Phenomics
23 October 2023
(In Press)
ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution.
Wu, J.Z., Zeziulia, M., Kwon, W., Jentsch, T.J., Grinstein, S. and Freeman, S.A.
Journal of Cell Biology 222
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5 June 2023
Consistency across multi-omics layers in a drug-perturbed gut microbial community.
Wuyts, S., Alves, R., Zimmermann-Kogadeeva, M., Nishijima, S., Blasche, S., Driessen, M., Geyer, P.E, Hercog, R., Kartal, E., Maier, L., Müller, J.B., Garcia Santamarina, S., Schmidt, T.S.B., Sevin, D.C., Telzerow, A., Treit, P.V., Wenzel, T., Typas, A., Patil, K.R, Mann, M., Kuhn, M. and Bork, P.
Molecular Systems Biology 19
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12 September 2023
Maternal-derived galectin 1 shapes the placenta niche through Sda terminal glycosylation: Implication for preeclampsia.
Xie, Y., Zhao, F., Freitag, N., Borowski, S., Wang, Y., Harms, C., Pang, P.C., Desforges, J., Wen, T., Schwedhelm, E., Singh, M., Dechend, R., Dell, A., Haslam, S.M., Dveksler, G., Garcia, M.G. and Blois, S.M.
PNAS Nexus 2
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August 2023
Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
Yeh, Y.T., Sona, C., Yan, X., Li, Y., Pathak, A., McDermott, M.I., Xie, Z., Liu, L., Arunagiri, A., Wang, Y., Cazenave-Gassiot, A., Ghosh, A., von Meyenn, F., Kumarasamy, S., Najjar, S.M., Jia, S., Wenk, M.R., Traynor-Kaplan, A., Arvan, P., Barg, S., Bankaitis, V.A. and Poy, M.N.
Nature Communications 14
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17 July 2023
Ethanol deprivation and central 5-HT deficiency differentially affect the mRNA editing of the 5-HT(2C) receptor in the mouse brain.
Zaniewska, M., Alenina, N., Fröhler, S., Chen, W. and Bader, M.
Pharmacological Reports 75
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December 2023
Mechanisms of enhancer function in neuronal systems in health and disease.
Zea Redondo, L. and Pombo, A.
Current Opinion in Systems Biology 32-33
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March 2023
Anwendung von „large language models“ in der Klinik [Clinical application of large language models : Does ChatGPT replace medical report formulation? An experience report].
Zernikow, J., Grassow, L., Gröschel, J., Henrion, P., Wetzel, P.J. and Spethmann, S.
Innere Medizin 64
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November 2023
Molecular basis of ClC-6 function and its impairment in human disease.
Zhang, B., Zhang, S., Polovitskaya, M.M., Yi, J., Ye, B., Li, R., Huang, X., Yin, J., Neuens, S., Balfroid, T., Soblet, J., Vens, D., Aeby, A., Li, X., Cai, J., Song, Y., Li, Y., Tartaglia, M., Li, Y., Jentsch, T.J., Yang, M. and Liu, Z.
Science Advances 9
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13 October 2023
Assessment of rhabdomyolysis-induced acute kidney injury with chemical exchange saturation transfer magnetic resonance imaging.
Zhang, Q., Tao, Q., Xie, Y., Chen, Z., Seeliger, E., Niendorf, T., Chen, W. and Feng, Y.
Quantitative Imaging in Medicine and Surgery 13
(12): 8336-8349.
December 2023
Diagnostic and prognostic performance of renal compartment volume and the apparent diffusion coefficient obtained from magnetic resonance imaging in mild, moderate and severe diabetic kidney disease.
Zhao, K., Li, S., Liu, Y., Li, Q., Lin, H., Wu, Z., Seeliger, E., Niendorf, T., Liu, Z. and Wang, W.
Quantitative Imaging in Medicine and Surgery 13
(6): 3973-3987.
1 June 2023
Serotonin-induced stereospecific formation and bioactivity of the eicosanoid 17,18-epoxyeicosatetraenoic acid in the regulation of pharyngeal pumping of C. elegans.
Zhou, Y., Rothe, M., Schunck, W.H., Ruess, L. and Menzel, R.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1868
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May 2023
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.
Zhu, H., Wang, G., Nguyen-Ngoc, K.V., Kim, D., Miller, M., Goss, G., Kovsky, J., Harrington, A.R., Saunders, D.C., Hopkirk, A.L., Melton, R., Powers, A.C., Preissl, S., Spagnoli, F.M., Gaulton, K.J. and Sander, M.
Developmental Cell 58
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8 May 2023
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
Ziegler, K.A., Ahles, A., Dueck, A., Esfandyari, D., Pichler, P., Weber, K., Kotschi, S., Bartelt, A., Sinicina, I., Graw, M., Leonhardt, H., Weckbach, L.T., Massberg, S., Schifferer, M., Simons, M., Hoeher, L., Luo, J., Ertürk, A., Schiattarella, G.G., Sassi, Y., Misgeld, T. and Engelhardt, S.
Science 381
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21 July 2023
Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure.
Zweck, E., Karschnia, M., Scheiber, D., Heidecke, H., Dechend, R., Barthuber, C., Kaufmann, S., Kelm, M., Roden, M., Westenfeld, R., Szendrödi, J. and Boege, F.
ESC Heart Failure 10
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April 2023
Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease.
van Kraaij, S.J.W., Pereira, D.R., Smal, B., Summo, L., Konkel, A., Lossie, J., Busjahn, A., Grammatopoulos, T.N., Klaassen, E., Fischer, R., Schunck, W.H., Gal, P. and Moerland, M.
Clinical and Translational Science 16
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July 2023
Cardiovascular magnetic resonance in the guidelines of the European Society of Cardiology: a comprehensive summary and update.
von Knobelsdorff-Brenkenhoff, F. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 25
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24 July 2023
2022
HDHL-INTIMIC: a European knowledge platform on food, diet, intestinal microbiomics, and human health.
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Nutrients 14
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29 April 2022
Blood flow meets mitophagy.
Akmeriç, E.B. and Gerhardt, H.
Journal of Cell Biology 221
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4 July 2022
Midwall fibrosis and cardiac mechanics: rigid body rotation is a novel marker of disease severity in pediatric primary dilated cardiomyopathy.
Al-Wakeel-Marquard, N., Seidel, F., Kühnisch, J., Kuehne, T., Berger, F., Messroghli, D.R. and Klaassen, S.
Frontiers in Cardiovascular Medicine 8
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17 February 2022
Angiotensin 1-7 increases fiber cross sectional area and force in juvenile mouse skeletal muscle.
Albadrani, H., Ammar, T., Rajgara, R., Bader, M., Wiper-Bergeron, N. and Renaud, J.M.
American Journal of Physiology Cell Physiology 323
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December 2022
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H., Flórez, A.F., Kreth, S., Brückner, L.M., Yildiz, U., Gartlgruber, M., Odoni, D.I., Poschet, G., Garbowicz, K., Shao, C., Klein, C., Meier, J., Zeisberger, P., Nadler-Holly, M., Ziehm, M., Paul, F., Burhenne, J., Bell, E., Shaikhkarami, M., Würth, R., Stainczyk, S.A., Wecht, E.M., Kreth, J., Büttner, M., Ishaque, N., Schlesner, M., Nicke, B., Stresemann, C., Llamazares-Prada, M., Reiling, J.H., Fischer, M., Amit, I., Selbach, M., Herrmann, C., Wölfl, S., Henrich, K.O., Höfer, T., Trumpp, A. and Westermann, F.
Nature Cancer 3
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28 April 2022
Age-related mechanisms in the context of rheumatic disease.
Alsaleh, G., Richter, F.C. and Simon, A.K.
Nature Reviews Rheumatology 18
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December 2022
Lifting the veil of secrecy: maternal and neonatal outcome of oocyte donation pregnancies in Germany.
Altmann, J., Kummer, J., Herse, F., Hellmeyer, L., Schlembach, D., Henrich, W. and Weichert, A.
Archives of Gynecology and Obstetrics 306
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July 2022
Acute myocarditis associated with desmosomal gene variants.
Ammirati, E., Raimondi, F., Piriou, N., Sardo Infirri, L., Mohiddin, S.A., Mazzanti, A., Shenoy, C., Cavallari, U.A., Imazio, M., Aquaro, G.D., Olivotto, I., Pedrotti, P., Sekhri, N., Van de Heyning, C.M., Broeckx, G., Peretto, G., Guttmann, O., Dellegrottaglie, S., Scatteia, A., Gentile, P., Merlo, M., Goldberg, R.I., Reyentovich, A., Sciamanna, C., Klaassen, S., Poller, W., Trankle, C.R., Abbate, A., Keren, A., Horowitz-Cederboim, S., Cadrin-Tourigny, J., Tadros, R., Annoni, G.A., Bonoldi, E., Toquet, C., Marteau, L., Probst, V., Trochu, J.N., Kissopoulou, A., Grosu, A., Kukavica, D., Trancuccio, A., Gil, C., Tini, G., Pedrazzini, M., Torchio, M., Sinagra, G., Gimeno, J.R., Bernasconi, D., Valsecchi, M.G., Klingel, K., Adler, E.D., Camici, P.G. and Cooper, L.T.
JACC Heart Fail 10
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October 2022
Integrative analysis of macrophage ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classes.
Ansari, S.A., Dantoft, W., Ruiz-Orera, J., Syed, A.P., Blachut, S., van Heesch, S., Hübner, N. and Uhlenhaut, N.H.
Computational and Structural Biotechnology Journal 20
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3 October 2022
Prognostic value of stress cardiac magnetic resonance in patients with known coronary artery disease.
Antiochos, P., Ge, Y., Heydari, B., Steel, K., Bingham, S., Abdullah, S.M., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 15
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January 2022
Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling.
Anton, S.E., Kayser, C., Maiellaro, I., Nemec, K., Möller, J., Koschinski, A., Zaccolo, M., Annibale, P., Falcke, M., Lohse, M.J. and Bock, A.
Cell 185
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31 March 2022
Carbon-mixed dental cement for fixing fiber optic ferrules prevents visually triggered locomotive enhancement in mice upon optogenetic stimulation.
Araragi, N., Alenina, N. and Bader, M.
Heliyon 8
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January 2022
Kinin B1 receptor modulates mitochondrial activity responsivity in fasting and voluntary exercise.
Arruda, A.C., Budu, A., de Menezes, T.N., Bader, M., Araujo, R.C. and Freitas-Lima, L.C.
Life Sciences 309
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15 November 2022
Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
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Proceedings of the National Academy of Sciences of the United States of America 119
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12 July 2022
Unraveling the hidden temporal range of fast β(2)-adrenergic receptor mobility by time-resolved fluorescence.
Balakrishnan, A., Hemmen, K., Choudhury, S., Krohn, J.H., Jansen, K., Friedrich, M., Beliu, G., Sauer, M., Lohse, M.J. and Heinze, K.G.
Communications Biology 5
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28 February 2022
Aurora kinase A is involved in controlling the localization of aquaporin-2 in renal principal cells.
Baltzer, S., Bulatov, T., Schmied, C., Krämer, A., Berger, B.T., Oder, A., Walker-Gray, R., Kuschke, C., Zühlke, K., Eichhorst, J., Lehmann, M., Knapp, S., Weston, J., von Kries, J.P., Süssmuth, R.D. and Klussmann, E.
International Journal of Molecular Sciences 23
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11 January 2022
Role of endothelial kinin B(1) receptor on the membrane potential of transgenic rat aorta.
Batista, C., Sales, V.M., Merino, V.F., Bader, M., Feres, T. and Pesquero, J.B.
Physiological Research 71
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August 2022
Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity.
Batlle, D., Monteil, V., Garreta, E., Hassler, L., Wysocki, J., Chandar, V., Schwartz, R.E., Mirazimi, A., Montserrat, N., Bader, M. and Penninger, J.M.
Cell 185
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26 May 2022
Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics.
Bayram, S., Razzaque, Y.S., Geisberger, S., Pietzke, M., Fürst, S., Vechiatto, C., Forbes, M., Mastrobuoni, G. and Kempa, S.
Frontiers in Molecular Biosciences 9
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12 August 2022
AQUA mutant protein quantification of endomyocardial biopsy-sized samples from a patient with hypertrophic cardiomyopathy.
Becker, E., Francino, A., Pich, A., Perrot, A., Kraft, T. and Radocaj, A.
Frontiers in Cardiovascular Medicine 9
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21 February 2022
Crosstalk between the renin-angiotensin, complement and kallikrein-kinin systems in inflammation.
Bekassy, Z., Lopatko Fagerström, I., Bader, M. and Karpman, D.
Nature Reviews Immunology 22
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July 2022
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
Belda, E., Voland, L., Tremaroli, V., Falony, G., Adriouch, S., Assmann, K.E., Prifiti, E., Aron-Wisnewsky, J., Debédat, J., Le Roy, T., Nielsen, T., Amouyal, C., André, S., Andreelli, F., Blüher, M., Chakaroun, R., Chilloux, J., Coelho, L.P., Dao, M.C., Das, P., Fellahi, S., Forslund, S., Galleron, N., Hansen, T.H., Holmes, B., Ji, B., Krogh Pedersen, H., Le, P., Le Chatelier, E., Lewinter, C., Mannerås-Holm, L., Marquet, F., Myridakis, A., Pelloux, V., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J.E., Sokolovska, N., Søndertoft, N.B., Touch, S., Vieira-Silva, S., Galan, P., Holst, J., Gøtze, J.P., Køber, L., Vestergaard, H., Hansen, T., Hercberg, S., Oppert, J.M., Nielsen, J., Letunic, I., Dumas, M.E., Stumvoll, M., Pedersen, O.B., Bork, P., Ehrlich, S.D., Zucker, J.D., Bäckhed, F., Raes, J. and Clément, K.
Gut 71
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7 November 2022
Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.
Benaglio, P., Zhu, H., Okino, M.L., Yan, J., Elgamal, R., Nariai, N., Beebe, E., Korgaonkar, K., Qiu, Y., Donovan, M.K.R., Chiou, J., Wang, G., Newsome, J., Kaur, J., Miller, M., Preissl, S., Corban, S., Aylward, A., Taipale, J., Ren, B., Frazer, K.A., Sander, M. and Gaulton, K.J.
Cell Genomics 2
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14 December 2022
Electrocardiographic changes during initiation of lithium augmentation of antidepressant pharmacotherapy.
Berger, M., Kermer, J., Behr, J., Schulz-Menger, J., Bilal, S., Osterland, S.L., O'Malley, G., Bschor, T., Schlattmann, P., Stamm, T., Steinacher, B., de Millas, W., Richter, C., Heinz, A., Adli, M., Buspavanich, P. and Ricken, R.
Journal of Clinical Psychopharmacology 42
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January 2022
Impact of the external school food environment on the associations of internal school food environment with high schoolers’ diet and BMI.
Betts, G.M., Schwedhelm, C., Lipsky, L.M., Haynie, D.L. and Nansel, T.R.
Public Health Nutrition 25
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November 2022
Elevated blood pressure in pregnant women with gestational diabetes according to the WHO criteria: importance of overweight.
Birukov, A., Glintborg, D., Schulze, M.B., Jensen, T.K., Kuxhaus, O., Andersen, L.B., Kräker, K., Polemiti, E., Jensen, B.L., Jørgensen, J.S., Dechend, R. and Andersen, M.S.
Journal of Hypertension 40
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August 2022
Up next: the dawn of systems biology in HFpEF research.
Bode, D., Sotomayor-Flores, C. and Schiattarella, G.G.
Journal of Molecular and Cellular Cardiology 168
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July 2022
SLM2 is a novel cardiac splicing factor involved in heart failure due to dilated cardiomyopathy.
Boeckel, J.N., Möbius-Winkler, M., Müller, M., Rebs, S., Eger, N., Schoppe, L., Tappu, R., Kokot, K.E., Kneuer, J.M., Gaul, S., Bordalo, D.M., Lai, A., Haas, J., Ghanbari, M., Drewe-Boss, P., Liss, M., Katus, H.A., Ohler, U., Gotthardt, M., Laufs, U., Streckfuss-Bömeke, K. and Meder, B.
Genomics Proteomics & Bioinformatics 20
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February 2022
Lifelong effect of therapy in young patients with the cOL4A5 alport missense variant p.(Gly624Asp): a prospective cohort study.
Boeckhaus, J., Hoefele, J., Riedhammer, K.M., Nagel, M., Beck, B., Choi, M., Gollasch, M., Bergmann, C., Sonntag, J.E., Troesch, V., Stock, J. and Gross, O.
Nephrology Dialysis Transplantation 37
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December 2022
pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation.
Boix, O., Martinez, M., Vidal, S., Giménez-Alejandre, M., Palenzuela, L., Lorenzo-Sanz, L., Quevedo, L., Moscoso, O., Ruiz-Orera, J., Ximénez-Embún, P., Ciriaco, N., Nuciforo, P., Stephan-Otto Attolini, C., Albà, M.M., Muñoz, J., Tian, T.V., Varela, I., Vivancos, A., Ramón Y Cajal, S., Muñoz, P., Rivas, C. and Abad, M.
Nature Communications 13
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11 November 2022
The impact of membrane protein diffusion on GPCR signaling.
Boltz, H.H., Sirbu, A., Stelzer, N., de Lanerolle, P., Winkelmann, S. and Annibale, P.
Cells 11
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17 May 2022
Examination of the contributions of maternal/placental-derived galectin-1 to pregnancy outcome.
Borowski, S., Freitag, N., Urban, I., Michel, G., Barrientos, G. and Blois, S.M.
Methods in Molecular Biology 2442
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2022
Glucose-induced hemodynamic and metabolic response of skeletal muscle in heart failure patients with reduced vs. preserved ejection fraction-a pilot study.
Boschmann, M., Klug, L., Edelmann, F., Sandek, A., von Haehling, S., Düngen, H.D., Springer, J., Anker, S.D., Doehner, W. and Jauert, N.
Journal of Cardiovascular Development and Disease 9
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13 December 2022
Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs.
Broto, M., Kaminski, M.M., Adrianus, C., Kim, N., Greensmith, R., Dissanayake-Perera, S., Schubert, A.J., Tan, X., Kim, H., Dighe, A.S., Collins, J.J. and Stevens, M.M.
Nature Nanotechnology 17
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October 2022
Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I., Jaeschke, L., Nimptsch, K., Janke, J., Herrmann, P., Kobelt, D., Kielstein, H., Pischon, T. and Stein, U.
International Journal of Oncology 60
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February 2022
Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
Cabral-Marques, O., Halpert, G., Schimke, L.F., Ostrinski, Y., Vojdani, A., Baiocchi, G.C., Freire, P.P., Filgueiras, I.S., Zyskind, I., Lattin, M.T., Tran, F., Schreiber, S., Marques, A.H.C., Plaça, D.R., Fonseca, D.L.M., Humrich, J.Y., Müller, A., Giil, L.M., Graßhoff, H., Schumann, A., Hackel, A., Junker, J., Meyer, C., Ochs, H.D., Lavi, Y.B., Scheibenbogen, C., Dechend, R., Jurisica, I., Schulze-Forster, K., Silverberg, J.I., Amital, H., Zimmerman, J., Heidecke, H., Rosenberg, A.Z., Riemekasten, G. and Shoenfeld, Y.
Nature Communications 13
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9 March 2022
Metaproteomics approach and pathway modulation in obesity and diabetes: a narrative review.
Calabrese, F.M., Porrelli, A., Vacca, M., Comte, B., Nimptsch, K., Pinart, M., Pischon, T., Pujos-Guillot, E. and De Angelis, M.
Nutrients 14
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January 2022
Cardiac metabolism in HFpEF: from fuel to signalling.
Capone, F., Sotomayor-Flores, C., Bode, D., Wang, R., Rodolico, D., Strocchi, S. and Schiattarella, G.G.
Cardiovascular Research 118
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December 2022
AKAP18δ anchors and regulates CaMKII activity at phospholamban-SERCA2 and RYR.
Carlson, C.R., Aronsen, J.M., Bergan-Dahl, A., Moutty, M.C., Lunde, M., Lunde, P.K., Jarstadmarken, H., Wanichawan, P., Pereira, L., Kolstad, T.R.S., Dalhus, B., Subramanian, H., Hille, S., Christensen, G., Müller, O.J., Nikolaev, V., Bers, D.M., Sjaastad, I., Shen, X., Louch, W.E., Klussmann, E. and Sejersted, O.M.
Circulation Research 130
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7 January 2022
The blood-brain barrier-a metabolic ecosystem.
Castro, M. and Potente, M.
EMBO Journal 41
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2 May 2022
Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
Cefalu, W.T., Andersen, D.K., Arreaza-Rubín, G., Pin, C.L., Sato, S., Verchere, C.B., Woo, M. and Rosenblum, N.D.
Diabetes 71
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January 2022
Oxidative RNA damage in the pathogenesis and treatment of type 2 diabetes.
Chen, X., Yu, H., Li, Z., Ye, W., Liu, Z., Gao, J., Wang, Y., Li, X., Zhang, L., Alenina, N., Bader, M., Ding, H., Li, P. and Aung, L.H.H.
Frontiers in Physiology 13
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28 March 2022
Physical mechanisms of chromatin spatial organization.
Chiariello, A.M., Bianco, S., Esposito, A., Fiorillo, L., Conte, M., Irani, E., Musella, F., Abraham, A., Prisco, A. and Nicodemi, M.
FEBS Journal 289
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March 2022
A high-resolution map of human RNA translation.
Chothani, S.P., Adami, E., Widjaja, A.A., Langley, S.R., Viswanathan, S., Pua, C.J., Zhihao, N.T., Harmston, N., D'Agostino, G., Whiffin, N., Mao, W., Ouyang, J.F., Lim, W.W., Lim, S., Lee, C.Q.E., Grubman, A., Chen, J., Kovalik, J.P., Tryggvason, K., Polo, J.M., Ho, L., Cook, S.A., Rackham, O.J.L. and Schafer, S.
Molecular Cell 82
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4 August 2022
A novel complex genomic rearrangement affecting the KCNJ2 regulatory region causes a variant of Cooks syndrome.
Cinque, L., Micale, L., Manara, E., Esposito, A., Palumbo, O., Chiariello, A.M., Bianco, S., Guerri, G., Bertelli, M., Giuffrida, M.G., Bernardini, L., Notarangelo, A., Nicodemi, M. and Castori, M.
Human Genetics 141
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February 2022
Towards the biogeography of prokaryotic genes.
Coelho, L.P., Alves, R., Del Río, Á.R., Myers, P.N., Cantalapiedra, C.P., Giner-Lamia, J., Schmidt, T.S., Mende, D.R., Orakov, A., Letunic, I., Hildebrand, F., Van Rossum, T., Forslund, S.K., Khedkar, S., Maistrenko, O.M., Pan, S., Jia, L., Ferretti, P., Sunagawa, S., Zhao, X.M., Nielsen, H.B., Huerta-Cepas, J. and Bork, P.
Nature 601
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13 January 2022
Polymer models of chromatin imaging data in single cells.
Conte, M., Chiariello, A.M., Abraham, A., Bianco, S., Esposito, A., Nicodemi, M., Matteuzzi, T. and Vercellone, F.
Algorithms 15
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16 September 2022
Efficient computational implementation of polymer physics models to explore chromatin structure.
Conte, M., Esposito, A., Fiorillo, L., Campanile, R., Annunziatella, C., Corrado, A., Chiariello, M.G., Bianco, S. and Chiariello, A.M.
International Journal of Parallel, Emergent and Distributed Systems 37
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January 2022
A polymer physics model to dissect genome organization in healthy and pathological phenotypes.
Conte, M., Fiorillo, L., Bianco, S., Chiariello, A.M., Esposito, A., Musella, F., Flora, F., Abraham, A. and Nicodemi, M.
Methods in Molecular Biology 2301
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Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding.
Conte, M., Irani, E., Chiariello, A.M., Abraham, A., Bianco, S., Esposito, A. and Nicodemi, M.
Nature Communications 13
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13 July 2022
Hypothalamic galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop.
Corradi, L., Bruzzone, M., Maschio, M.D., Sawamiphak, S. and Filosa, A.
Current Biology 32
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11 April 2022
Using pERK immunostaining to quantify neuronal activity induced by stress in zebrafish larvae.
Corradi, L., Zaupa, M., Sawamiphak, S. and Filosa, A.
STAR Protocols 3
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16 December 2022
Svep1 stabilises developmental vascular anastomosis in reduced flow conditions.
Coxam, B., Collins, R.T., Hußmann, M., Huisman, Y., Meier, K., Jung, S., Bartels-Klein, E., Szymborska, A., Finotto, L., Helker, C.S.M., Stainier, D.Y.R., Schulte-Merker, S. and Gerhardt, H.
Development 149
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24 March 2022
Myogenic vasoconstriction requires canonical G(q/11) signaling of the angiotensin II type 1 receptor.
Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y.M., Schleifenbaum, J., Bader, M., Welsh, D.G., Huang, Y. and Gollasch, M.
Journal of the American Heart Association 11
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15 February 2022
Associations of ultra-processed food intake with maternal weight change and cardiometabolic health and infant growth.
Cummings, J.R., Lipsky, L.M., Schwedhelm, C., Liu, A. and Nansel, T.R.
International Journal of Behavioral Nutrition and Physical Activity 19
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26 May 2022
Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension.
Dahale, S., Ruiz-Orera, J., Silhavy, J., Hübner, N., van Heesch, S., Pravenec, M. and Atanur, S.S.
Life Science Alliance 5
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April 2022
Diagnostik, Therapie und die Bedeutung der Lebensqualität von Patienten mit chronischem Koronarsyndrom [Diagnostics, therapy and the importance of quality of life in patients with chronic coronary syndrome. Results oft the general practitioner care study ALTHEA].
Dechend, R.
MMW Fortschritte der Medizin 164
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Endothelin antagonists and the quest for a new therapeutic option in resistant hypertension.
Dechend, R. and Delles, C.
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Salt, aldosterone, and the renin-angiotensin system in pregnancy.
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Prevalence of hypertension and possible risk factors of hypertension unawareness among individuals aged 30-75 years from two Panamanian provinces: results from population-based cross-sectional studies, 2010 and 2019.
Del Rio, A.I., Moreno Velásquez, I., Roa, R., Montenegro Mendoza, R., Motta, J. and Quintana, H.K.
PLoS ONE 17
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B(1) inhomogeneity correction of RARE MRI at low SNR: quantitative in vivo (19)F MRI of mouse neuroinflammation with a cryogenically-cooled transceive surface radiofrequency probe.
Delgado, P.R., Kuehne, A., Aravina, M., Millward, J.M., Vazquez, A., Starke, L., Waiczies, H., Pohlmann, A., Niendorf, T. and Waiczies, S.
Magnetic Resonance in Medicine 87
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Functional repertoire convergence of distantly related eukaryotic plankton lineages abundant in the sunlit ocean.
Delmont, T.O., Gaia, M., Hinsinger, D.D., Frémont, P., Vanni, C., Fernandez-Guerra, A., Eren, A.M., Kourlaiev, A., d'Agata, L., Clayssen, Q., Villar, E., Labadie, K., Cruaud, C., Poulain, J., Da Silva, C., Wessner, M., Noel, B., Aury, J.M., de Vargas, C., Bowler, C., Karsenti, E., Pelletier, E., Wincker, P. and Jaillon, O.
Cell Genomics 2
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11 May 2022
Traveling volunteers: a multi-vendor, multi-center study on reproducibility and comparability of 4D flow derived aortic hemodynamics in cardiovascular magnetic resonance.
Demir, A., Wiesemann, S., Erley, J., Schmitter, S., Trauzeddel, R.F., Pieske, B., Hansmann, J., Kelle, S. and Schulz-Menger, J.
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A comparison of solvent-based extraction methods to assess the central carbon metabolites in mouse bone and muscle.
Dias, D.B., Fritsche-Guenther, R., Gutmann, F., Duda, G.N., Kirwan, J. and Poh, P.S.P.
Metabolites 12
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Motion-compensated fat-water imaging for 3D cardiac MRI at ultra-high fields.
Dietrich, S., Aigner, C.S., Mayer, J., Kolbitsch, C., Schulz-Menger, J., Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 87
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June 2022
Hmga2 protein loss alters nuclear envelope and 3D chromatin structure.
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BMC Biology 20
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2 August 2022
Brief research report: Quantitative analysis of potential coronary microvascular disease in suspected long-COVID syndrome.
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Frontiers in Cardiovascular Medicine 9
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31 May 2022
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
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Nature Communications 13
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25 July 2022
Increase in mental disorders during the COVID-19 pandemic -- the role of occupational and financial strains. An analysis of the German National Cohort (NAKO) Study.
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18 March 2022
The lncRNA landscape of cardiac resident macrophages and identification of Schlafenlnc as a regulator of macrophage migratory function.
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bioRxiv
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22 December 2022
Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
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1 December 2022
Die Rolle der Hyper- und Hypohydrogenämie im klinischen Alltag - Warum pH? [The role of hyperhydrogenemia and hypohydrogenemia in the clinical setting - Why pH?].
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September 2022
The spontaneous course of human herpesvirus 6 DNA-associated myocarditis and the effect of immunosuppressive intervention.
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Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
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Evaluating metallic artefact of biodegradable magnesium-based implants in magnetic resonance imaging.
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The physics of DNA folding: polymer models and phase-separation.
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Isotropic 3D compressed sensing (CS) based sequence is comparable to 2D-LGE in left ventricular scar quantification in different disease entities.
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Hypertension in pregnancy: diagnosis, blood pressure goals, and pharmacotherapy: a scientific statement from the American Heart Association.
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Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications.
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Improving robustness of automatic cardiac function quantification from cine magnetic resonance imaging using synthetic image data.
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Scientific Reports 12
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14 February 2022
Aging-regulated TUG1 is dispensable for endothelial cell function.
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Every islet matters: improving the impact of human islet research.
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Nature Metabolism 4
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Fluorescence spectroscopy of low-level endogenous β-adrenergic receptor expression at the plasma membrane of differentiating human iPSC-derived cardiomyocytes.
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Expression of circ_Satb1 is decreased in mesial temporal lobe epilepsy and regulates dendritic spine morphology.
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3 March 2022
Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension.
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January 2022
Age of red cells for transfusion and outcomes in patients with ARDS.
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Journal of Clinical Medicine 11
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4 January 2022
Was ist gesichert in der Therapie der chronischen Nierenerkrankung? [What is confirmed in the treatment of chronic kidney disease?].
Greite, R. and Schmidt-Ott, K.
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December 2022
Isolation of neoantigen-specific human T cell receptors from different human and murine repertoires.
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6 April 2022
Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients.
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Fast acquisition of left and right ventricular function parameters applying cardiovascular magnetic resonance in clinical routine - validation of a 2-shot compressed sensing cine sequence.
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Scandinavian Cardiovascular Journal 56
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14 July 2022
Different impacts on the heart after COVID-19 infection and vaccination: insights from cardiovascular magnetic resonance.
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Frontiers in Cardiovascular Medicine 9
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14 July 2022
Stellenwert der kardiovaskulären Magnetresonanz in der kardiovaskulären Diagnostik [Role of cardiovascular magnetic resonance in cardiovascular diagnostics].
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25 April 2022
Acute kidney injury in patients receiving pembrolizumab combination therapy versus pembrolizumab monotherapy for advanced lung cancer.
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October 2022
Lösliche Guanylatzyklase(sGC)-Stimulation mit Vericiguat: Von der pharmakologischen Idee bis zur Therapie der chronischen Herzinsuffizienz [Soluble guanylate cyclase (sGC) stimulation with vericiguat : from the pharmacological idea to the treatment of chronic heart failure].
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Kardiologie 16
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December 2022
Introduction of Lazy Luna an automatic software-driven multilevel comparison of ventricular function quantification in cardiovascular magnetic resonance imaging.
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Scientific Reports 12
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22 April 2022
Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats.
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Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism.
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7 February 2022
An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
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Science Advances 8
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7 January 2022
High-resolution transthoracic echocardiography accurately detects pulmonary arterial pressure and decreased right ventricular contractility in a mouse model of pulmonary fibrosis and secondary pulmonary hypertension.
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6 December 2022
A critical period of translational control during brain development at codon resolution.
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Locus-conserved circular RNA cZNF292 controls endothelial cell flow responses.
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7 January 2022
Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors.
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1 April 2022
A novel AQP2 sequence variant causing aquaporin-2 retention in the cytoplasm and autosomal dominant nephrogenic diabetes insipidus.
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October 2022
Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury.
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9 September 2022
Acute kidney injury biomarkers in the single cell transcriptomic era.
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9 November 2022
Tracking by weakly-supervised learning and graph optimization for whole-embryo c. elegans lineages.
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Mechanisms of spermidine-induced autophagy and geroprotection.
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Nature Aging 2
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December 2022
Inflammation in children with chronic kidney disease linked to gut dysbiosis and metabolite imbalance.
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December 2022
Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
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27 October 2022
Origin and function of activated fibroblast states during zebrafish heart regeneration.
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3D model-based super-resolution motion-corrected cardiac T1 mapping.
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9 December 2022
Physical performance and non-esterified fatty acids in men and women after transcatheter aortic valve implantation (TAVI).
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2 January 2022
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke, K., Obermayer, B., Mache, C., Fathykova, D., Kessler, M., Dökel, S., Wyler, E., Baumgardt, M., Löwa, A., Hoffmann, K., Graff, P., Schulze, J., Mieth, M., Hellwig, K., Demir, Z., Biere, B., Brunotte, L., Mecate-Zambrano, A., Bushe, J., Dohmen, M., Hinze, C., Elezkurtaj, S., Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Schmidt-Ott, K.M., Busch, J., Klauschen, F., Horst, D., Radbruch, H., Radke, J., Heppner, F., Corman, V.M., Niemeyer, D., Müller, M.A., Goffinet, C., Mothes, R., Pascual-Reguant, A., Hauser, A.E., Beule, D., Landthaler, M., Ludwig, S., Suttorp, N., Witzenrath, M., Gruber, A.D., Drosten, C., Sander, L.E., Wolff, T., Hippenstiel, S. and Hocke, A.C.
European Respiratory Journal 60
(6): 2102725.
1 December 2022
Evaluation of pharmacological rescue of melanocortin-4 receptor nonsense mutations by aminoglycoside.
Höpfner, F., Paisdzior, S., Reininghaus, N., Sohail, I., Scheerer, P., Annibale, P., Biebermann, H. and Kühnen, P.
Life 12
(11): 1793.
5 November 2022
Dynamics of bacteria scanning a porous environment.
Irani, E., Mokhtari, Z. and Zippelius, A.
Physical Review Letters 128
(14): 144501.
5 April 2022
Analyses of circRNA expression throughout the light-dark cycle reveal a strong regulation of (Cdr1as), associated with light entrainment in the SCN.
Ivanov, A., Mattei, D., Radscheit, K., Compagnion, A.C., Pett, J.P., Herzel, H.P., Paolicelli, R.C., Piwecka, M., Meyer, U. and Beule, D.
International Journal of Molecular Sciences 23
(20): 12347.
October 2022
The bias from heaping on risk estimation: Effect of age at diagnosis of hypertension on risk of subsequent cardiovascular comorbidities.
Jaeschke, L., Becher, M., Moreno Velásquez, I., Ahrens, W., Bächle, C., Baurecht, H., Fricke, J., Greiser, K.H., Günther, K., Heier, M., Karch, A., Kluttig, A., Krist, L., Leitzmann, M., Michels, K., Mikolajczyk, R., Peters, A., Schipf, S., Völzke, H., Pischon, T. and Becher, H.
Annals of Epidemiology 74
: 84-96.
October 2022
Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice.
Jensen, M., Müller, C., Huebner, N., Patone, G., Saar, K., Choe, C.U., Schwedhelm, E. and Zeller, T.
Scientific Reports 12
(1): 5108.
24 March 2022
Prediction of activity-related energy expenditure under free-living conditions using accelerometer-derived physical activity.
Jeran, S., Steinbrecher, A., Haas, V., Mähler, A., Boschmann, M., Westerterp, K.R., Brühmann, B.A., Steindorf, K. and Pischon, T.
Scientific Reports 12
(1): 16578.
4 October 2022
Targeting cathepsin C in PR3-ANCA vasculitis.
Jerke, U., Eulenberg-Gustavus, C., Rousselle, A., Nicklin, P., Kreideweiss, S., Grundl, M.A., Eickholz, P., Nickles, K., Schreiber, A., Korkmaz, B. and Kettritz, R.
Journal of the American Society of Nephrology 33
(5): 936-947.
May 2022
Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Jin, Y., Ding, Y., Richards, M., Kaakinen, M., Giese, W., Baumann, E., Szymborska, A., Rosa, A., Nordling, S., Schimmel, L., Akmeriç, E.B., Pena, A., Nwadozi, E., Jamalpour, M., Holstein, K., Sáinz-Jaspeado, M., Bernabeu, M.O., Welsh, M., Gordon, E., Franco, C.A., Vestweber, D., Eklund, L., Gerhardt, H. and Claesson-Welsh, L.
Nature Cardiovascular Research 1
(12): 1156–1173.
December 2022
Transient activated fibroblasts contribute to zebrafish heart regeneration.
Junker, J.P. and Panáková, D.
Nature Genetics 54
(8): 1076-1077.
August 2022
Cardiac surgery-related acute kidney injury - risk factors, clinical course, management suggestions.
Just, I.A., Alborzi, F., Godde, M., Ott, S., Meyer, A., Stein, J., Mazgareanu, S., van der Giet, M., Schmidt-Ott, K.M., Falk, V. and Schoenrath, F.
Journal of Cardiothoracic and Vascular Anesthesia 36
(2): 444-451.
February 2022
Filaggrin loss-of-function mutations are associated with persistence of egg and milk allergy.
Kalb, B., Marenholz, I., Jeanrenaud, A.C.S.N., Meixner, L., Arnau-Soler, A., Rosillo-Salazar, O.D., Ghauri, A., Cibin, P., Blümchen, K., Schlags, R., Hansen, G., Seidenberg, J., Keil, T., Lau, S., Niggemann, B., Beyer, K. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 150
(5): 1125-1134.
November 2022
Tolerance induction through early feeding to prevent food allergy in infants with eczema (TEFFA): rationale, study design, and methods of a randomized controlled trial.
Kalb, B., Meixner, L., Trendelenburg, V., Unterleider, N., Dobbertin-Welsch, J., Heller, S., Dölle-Bierke, S., Roll, S., Lau, S., Lee, Y.A., Fauchère, F., Braun, J., Babina, M., Altrichter, S., Birkner, T., Worm, M. and Beyer, K.
Trials 23
(1): 210.
12 March 2022
Serotonin limits generation of chromaffin cells during adrenal organ development.
Kameneva, P., Melnikova, V.I., Kastriti, M.E., Kurtova, A., Kryukov, E., Murtazina, A., Faure, L., Poverennaya, I., Artemov, A.V., Kalinina, T.S., Kudryashov, N.V., Bader, M., Skoda, J., Chlapek, P., Curylova, L., Sourada, L., Neradil, J., Tesarova, M., Pasqualetti, M., Gaspar, P., Yakushov, V.D., Sheftel, B.I., Zikmund, T., Kaiser, J., Fried, K., Alenina, N., Voronezhskaya, E.E. and Adameyko, I.
Nature Communications 13
(1): 2901.
25 May 2022
Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load.
Kaneshige, A., Kaji, T., Zhang, L., Saito, H., Nakamura, A., Kurosawa, T., Ikemoto-Uezumi, M., Tsujikawa, K., Seno, S., Hori, M., Saito, Y., Matozaki, T., Maehara, K., Ohkawa, Y., Potente, M., Watanabe, S., Braun, T., Uezumi, A. and Fukada, S.I.
Cell Stem Cell 29
(2): 265-280.
3 February 2022
Automated imaging-based abdominal organ segmentation and quality control in 20,000 participants of the UK Biobank and German National Cohort Studies.
Kart, T., Fischer, M., Winzeck, S., Glocker, B., Bai, W., Bülow, R., Emmel, C., Friedrich, L., Kauczor, H.U., Keil, T., Kröncke, T., Mayer, P., Niendorf, T., Peters, A., Pischon, T., Schaarschmidt, B.M., Schmidt, B., Schulze, M.B., Umutle, L., Völzke, H., Küstner, T., Bamberg, F., Schölkopf, B., Rueckert, D. and Gatidis, S.
Scientific Reports 12
(1): 18733.
4 November 2022
A faecal microbiota signature with high specificity for pancreatic cancer.
Kartal, E., Schmidt, T.S.B., Molina-Montes, E., Rodríguez-Perales, S., Wirbel, J., Maistrenko, O.M., Akanni, W.A., Alashkar Alhamwe, B., Alves, R.J., Carrato, A., Erasmus, H.P., Estudillo, L., Finkelmeier, F., Fullam, A., Glazek, A.M., Gómez-Rubio, P., Hercog, R., Jung, F., Kandels, S., Kersting, S., Langheinrich, M., Márquez, M., Molero, X., Orakov, A., Van Rossum, T., Torres-Ruiz, R., Telzerow, A., Zych, K., Benes, V., Zeller, G., Trebicka, J., Real, F.X., Malats, N. and Bork, P.
Gut 71
(7): 1359-1372.
7 June 2022
Real-time measurements of intracellular cAMP gradients using FRET-based cAMP nanorulers.
Kayser, C., Lohse, M.J. and Bock, A.
Methods in Molecular Biology 2483
: 1-13.
2022
Placental transcriptome profiling in subtypes of diabetic pregnancies is strongly confounded by fetal sex.
Kedziora, S.M., Obermayer, B., Sugulle, M., Herse, F., Kräker, K., Haase, N., Langmia, I.M., Müller, D.N., Staff, A.C., Beule, D. and Dechend, R.
International Journal of Molecular Sciences 23
(23): 15388.
6 December 2022
The Case: Is this hemolytic uremic syndrome?
Kettritz, R., Düttmann, W., Brand, A. and Luft, F.C.
Kidney International 102
(5): 1195-1196.
November 2022
Complement is complimentary in membranous nephropathy.
Kettritz, R. and Schreiber, A.
Journal of the American Society of Nephrology 33
(9): 1631-1633.
September 2022
Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes.
Khedkar, S., Smyshlyaev, G., Letunic, I., Maistrenko, O.M., Coelho, L.P., Orakov, A., Forslund, S.K., Hildebrand, F., Luetge, M., Schmidt, T.S.B., Barabas, O. and Bork, P.
Nucleic Acids Research 50
(6): 3155-3168.
8 April 2022
Left ventricular noncompaction in children: the role of genetics, morphology, and function for outcome.
Klaassen, S., Kühnisch, J., Schultze-Berndt, A. and Seidel, F.
Journal of Cardiovascular Development and Disease 9
(7): 206.
30 June 2022
Proteolytic cleavage of the extracellular domain affects signaling of parathyroid hormone 1 receptor.
Klenk, C., Hommers, L. and Lohse, M.J.
Frontiers in Endocrinology 13
: 839351.
22 February 2022
Urinary single-cell sequencing captures kidney injury and repair processes in human acute kidney injury.
Klocke, J., Kim, S.J., Skopnik, C.M., Hinze, C., Boltengagen, A., Metzke, D., Grothgar, E., Prskalo, L., Wagner, L., Freund, P., Görlich, N., Muench, F., Schmidt-Ott, K.M., Mashreghi, M.F., Kocks, C., Eckardt, K.U., Rajewsky, N. and Enghard, P.
Kidney International 102
(6): 1359-1370.
December 2022
Meconium microbiome of very preterm infants across Germany.
Klopp, J., Ferretti, P., Meyer, C.U., Hilbert, K., Haiß, A., Marißen, J., Henneke, P., Hudalla, H., Pirr, S., Viemann, D., Zemlin, M., Forslund, S.K., Härtel, C., Bork, P., Gehring, S. and Van Rossum, T.
mSphere 7
(1): e0080821.
23 February 2022
Antibiotic resistance genes in river biofilms: a metagenomic approach toward the identification of sources and candidate hosts.
Kneis, D., Berendonk, T.U., Forslund, S.K. and Hess, S.
Environmental Science and Technology 56
(21): 14913-14922.
1 November 2022
Hidden agenda - the involvement of endoplasmic reticulum stress and unfolded protein response in inflammation-induced muscle wasting.
Kny, M. and Fielitz, J.
Frontiers in Immunology 13
: 878755.
9 May 2022
Functional indications for transposase domestications - characterization of the human piggyBac transposase derived (PGBD) activities.
Kolacsek, O., Wachtl, G., Fóthi, Á., Schamberger, A., Sándor, S., Pergel, E., Varga, N., Raskó, T., Izsvák, Z., Apáti, Á. and Orbán, T.I.
Gene 834
: 146609.
5 August 2022
Identification of novel genes whose expression in adipose tissue affects body fat mass and distribution: an RNA-Seq and Mendelian Randomization study.
Konigorski, S., Janke, J., Patone, G., Bergmann, M.M., Lippert, C., Hübner, N., Kaaks, R., Boeing, H. and Pischon, T.
European Journal of Human Genetics 32
(9): 1127-1135.
September 2022
15-keto-Prostaglandin E(2) exhibits bioactive role by modulating glomerular cytoarchitecture through EP2/EP4 receptors.
Kourpa, A., Kaiser-Graf, D., Sporbert, A., Philippe, A., Catar, R., Rothe, M., Mangelsen, E., Schulz, A., Bolbrinker, J., Kreutz, R. and Panáková, D.
Life Sciences 310
: 121114.
1 December 2022
Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society.
Kroke, A., Schmidt, A., Amini, A.M., Kalotai, N., Lehmann, A., Haardt, J., Bauer, J.M., Bischoff-Ferrari, H.A., Boeing, H., Egert, S., Ellinger, S., Kühn, T., Louis, S., Lorkowski, S., Nimptsch, K., Remer, T., Schulze, M.B., Siener, R., Stangl, G.I., Volkert, D., Zittermann, A., Buyken, A.E., Watzl, B. and Schwingshackl, L.
European Journal of Nutrition 61
(4): 2091-2101.
June 2022
Editorial: Sexual dimorphism in biomedical research and its therapeutic implications.
Kroon, J., Mahmoodzadeh, S. and Helsen, C.
Frontiers in Endocrinology 13
: 1009712.
19 August 2022
GMP-grade manufacturing and quality control of a non-virally engineered advanced therapy medicinal product for personalized treatment of age-related macular degeneration.
Kropp, M., Harmening, N., Bascuas, T., Johnen, S., De Clerck, E., Fernández, V., Ronchetti, M., Cadossi, R., Zanini, C., Scherman, D., Ivics, Z., Marie, C., Izsvák, Z. and Thumann, G.
Biomedicines 10
(11): 2777.
November 2022
Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses.
Kunath, B.J., Hickl, O., Queirós, P., Martin-Gallausiaux, C., Lebrun, L.A., Halder, R., Laczny, C.C., Schmidt, T.S.B., Hayward, M.R., Becher, D., Heintz-Buschart, A., de Beaufort, C., Bork, P., May, P. and Wilmes, P.
Microbiome 10
(1): 243.
28 December 2022
The gut microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS).
König, R.S., Albrich, W.C., Kahlert, C.R., Bahr, L.S., Löber, U., Vernazza, P., Scheibenbogen, C. and Forslund, S.K.
Frontiers in Immunology 12
: 628741.
3 January 2022
Magnetic field-induced interactions between phones containing magnets and cardiovascular implantable electronic devices: Flip it to be safe?
Lacour, P., Dang, P.L., Heinzel, F.R., Parwani, A.S., Bähr, F., Kucher, A., Hohendanner, F., Niendorf, T., Rahimi, F., Saha, N., Han, H., Rubarth, K., Sherif, M., Boldt, L.H., Pieske, B. and Blaschke, F.
Heart Rhythm 19
(3): 372-380.
March 2022
Interleukin 8 in postoperative delirium - preliminary findings from two studies.
Lammers-Lietz, F., Akyuz, L., Feinkohl, I., Lachmann, C., Pischon, T., Volk, H.D., von Häfen, C., Yürek, F., Winterer, G. and Spies, C.D.
Brain Behavior & Immunity - Health 20
: 100419.
March 2022
Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng, H., Zhang, H., Li, L., Zhang, S., Wang, Y., Chavda, S.J., Galas-Filipowicz, D., Lou, H., Ersek, A., Morris, E.V., Sezgin, E., Lee, Y.H., Li, Y., Lechuga-Vieco, A.V., Tian, M., Mi, J.Q., Yong, K., Zhong, Q., Edwards, C.M., Simon, A.K. and Horwood, N.J.
Nature Communications 13
(1): 7868.
22 December 2022
Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors.
Li, C., Wang, H., Gil, S., Germond, A., Fountain, C., Baldessari, A., Kim, J., Liu, Z., Georgakopoulou, A., Radtke, S., Raskó, T., Pande, A., Chiang, C., Chin, E., Yannaki, E., Izsvak, Z., Papayannopoulou, T., Kiem, H.P. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 24
: 127-141.
10 March 2022
Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function.
Lin, S.J., Vona, B., Porter, H.M., Izadi, M., Huang, K., Lacassie, Y., Rosenfeld, J.A., Khan, S., Petree, C., Ali, T.A., Muhammad, N., Khan, S.A., Muhammad, N., Liu, P., Haymon, M.L., Rüschendorf, F., Kong, I.K., Schnapp, L., Shur, N., Chorich, L., Layman, L., Haaf, T., Pourkarimi, E., Kim, H.G. and Varshney, G.K.
Human Mutation 43
(10): 1472-1489.
October 2022
HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin, Y.H., Major, J.L., Liebner, T., Hourani, Z., Travers, J.G., Wennersten, S.A., Haefner, K.R., Cavasin, M.A., Wilson, C.E., Jeong, M.Y., Han, Y., Gotthardt, M., Ferguson, S.K., Ambardekar, A.V., Lam, M.P., Choudhary, C., Granzier, H.L., Woulfe, K.C. and McKinsey, T.A.
Journal of Clinical Investigation 132
(10): e148333.
16 May 2022
Diffusion-weighted magnetic resonance imaging in rat kidney using two-dimensional navigated, interleaved echo-planar imaging at 7.0 T.
Liu, Q., Xu, Z., Zhao, K., Hoge, W.S., Zhang, X., Mei, Y., Lu, Q., Niendorf, T. and Feng, Y.
NMR in Biomedicine 35
(5): e4652.
May 2022
Hemodialysis and biotransformation of erythrocyte epoxy fatty acids in peripheral tissue.
Liu, T., Dogan, I., Rothe, M., Kunz, J.V., Knauf, F., Gollasch, M., Luft, F.C. and Gollasch, B.
Prostaglandins, Leukotrienes, and Essential Fatty Acids 181
: 102453.
June 2022
Hemodialysis and plasma oxylipin biotransformation in peripheral tissue.
Liu, T., Dogan, I., Rothe, M., Kunz, J.V., Knauf, F., Gollasch, M., Luft, F.C. and Gollasch, B.
Metabolites 12
(1): 34.
4 January 2022
Bioaccumulation of blood long-chain fatty acids during hemodialysis.
Liu, T., Dogan, I., Rothe, M., Reichardt, J., Knauf, F., Gollasch, M., Luft, F.C. and Gollasch, B.
Metabolites 12
(3): 269.
21 March 2022
Targeted analysis of cell-free circulating tumor DNA is suitable for early relapse and actionable target detection in patients with neuroblastoma.
Lodrini, M., Graef, J., Thole-Kliesch, T.M., Astrahantseff, K., Sprüssel, A., Grimaldi, M., Peitz, C., Linke, R.B., Hollander, J.F., Lankes, E., Künkele, A., Oevermann, L., Schwabe, G., Fuchs, J., Szymansky, A., Schulte, J.H., Hundsdoerfer, P., Eckert, C., Amthauer, H., Eggert, A. and Deubzer, H.E.
Clinical Cancer Research 28
(9): 1809-1820.
1 May 2022
3D genome topologies distinguish pluripotent epiblast and primitive endoderm cells in the mouse blastocyst.
Loof, G., Szabo, D., Garg, V., Kukalev, A., Zea-Redondo, L., Kempfer, R., Sparks, T.M., Zhang, Yi., Thieme, C.J., Carvalho, S., Weise, A., Balachandran, M., Liehr, T., Welch, L.R., Hadjantonakis, A.K. and Pombo, A.
bioRxiv
: 2022.10.19.512781.
20 October 2022
Epigenetic "transgenerational" inheritance.
Luft, F.C.
Circulation 146
(14): 1096-1098.
4 October 2022
Translating plasma sodium, stores, and hydration state from mouse to man.
Luft, F.C.
European Heart Journal 43
(35): 3349-3351.
14 September 2022
Amiloride and calciuria.
Luft, F.C. and Sällström, J.
Nephrology Dialysis Transplantation 37
(2): 205-207.
February 2022
AntiSplodge: a neural-network-based RNA-profile deconvolution pipeline designed for spatial transcriptomics.
Lund, J.B., Lindberg, E.L., Maatz, H., Pottbaecker, F., Hübner, N. and Lippert, C.
NAR Genomics and Bioinformatics 4
(4): lqac073.
December 2022
Renal deletion of LRRC8/VRAC channels induces proximal tubulopathy.
López-Cayuqueo, K.I., Planells-Cases, R., Pietzke, M., Oliveras, A., Kempa, S., Bachmann, S. and Jentsch, T.J.
Journal of the American Society of Nephrology 33
(8): 1528-1545.
August 2022
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
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Nature Genetics 54
(5): 560-572.
May 2022
SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.
Maharana, S., Kretschmer, S., Hunger, S., Yan, X., Kuster, D., Traikov, S., Zillinger, T., Gentzel, M., Elangovan, S., Dasgupta, P., Chappidi, N., Lucas, N., Maser, K.I., Maatz, H., Rapp, A., Marchand, V., Chang, Y.T., Motorin, Y., Hubner, N., Hartmann, G., Hyman, A.A., Alberti, S. and Lee-Kirsch, M.A.
Molecular Cell 82
(19): 3712-3728.e10.
6 October 2022
Skin sodium accumulates in psoriasis and reflects disease severity.
Maifeld, A., Wild, J., Karlsen, T.V., Rakova, N., Wistorf, E., Linz, P., Jung, R., Birukov, A., Gimenez-Rivera, V.A., Wilck, N., Bartolomaeus, T., Dechend, R., Kleinewietfeld, M., Forslund, S.K., Krause, A., Kokolakis, G., Philipp, S., Clausen, B.E., Brand, A., Waisman, A., Kurschus, F.C., Wegner, J., Schultheis, M., Luft, F.C., Boschmann, M., Kelm, M., Wiig, H., Kuehne, T., Müller, D.N., Karbach, S. and Markó, L.
Journal of Investigative Dermatology 142
(1): 166-178.
January 2022
Loss of endothelial cytochrome P450 reductase induces vascular dysfunction in mice.
Malacarne, P.F., Ratiu, C., Gajos-Draus, A., Müller, N., Lopez, M., Pflüger-Müller, B., Ding, X., Warwick, T., Oo, J., Siragusa, M., Angioni, C., Günther, S., Weigert, A., Geißlinger, G., Lütjohann, D., Schunck, W.H., Fleming, I., Brandes, R.P. and Rezende, F.
Hypertension 79
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June 2022
The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation towards the kidney lineage.
Mansour, F., Hinze, C., Telugu, N.S., Kresoja, J., Shaheed, I.B., Mosimann, C., Diecke, S. and Schmidt-Ott, K.M.
eLife 11
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12 October 2022
In vitro Kinase-to-Phosphosite database (iKiP-DB) predicts kinase activity in phosphoproteomic datasets.
Mari, T., Mösbauer, K., Wyler, E., Landthaler, M., Drosten, C. and Selbach, M.
Journal of Proteome Research 21
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3 June 2022
Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F., Jerke, U., Rolle, S., Daumke, O. and Kettritz, R.
Journal of Biological Chemistry 298
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March 2022
Effect of sunitinib treatment on skin sodium accumulation in patients with renal cancer: a pilot study.
Markó, L., Dörr, A., Linz, P., van den Meiracker, A.H., Garrelds, I.M., Kuehne, T., Dechend, R., Danser, A.H.J., Flörcken, A. and Müller, D.N.
Hypertension 79
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May 2022
Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases.
Mastracci, T.L., Apte, M., Amundadottir, L.T., Alvarsson, A., Artandi, S., Bellin, M.D., Bernal-Mizrachi, E., Caicedo, A., Campbell-Thompson, M., Cruz-Monserrate, Z., El Ouaamari, A., Gaulton, K.J., Geisz, A., Goodarzi, M.O., Hara, M., Hull-Meichle, R.L., Kleger, A., Klein, A.P., Kopp, J.L., Kulkarni, R.N., Muzumdar, M.D., Naren, A.P., Oakes, S.A., Olesen, S.S., Phelps, E.A., Powers, A.C., Stabler, C.L., Tirkes, T., Whitcomb, D.C., Yadav, D., Yong, J., Zaghloul, N.A., Sander, M. and Pandol, S.J.
Pancreas 51
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1 October 2022
Molecular and functional characterization of BDNF-overexpressing human retinal pigment epithelial cells established by sleeping beauty transposon-mediated gene transfer.
Mattern, L., Otten, K., Miskey, C., Fuest, M., Izsvák, Z., Ivics, Z., Walter, P., Thumann, G. and Johnen, S.
International Journal of Molecular Sciences 23
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1 November 2022
Cardio-respiratory motion-corrected 3D cardiac water-fat MRI using model-based image reconstruction.
Mayer, J., Blaszczyk, E., Cipriani, A., Ferrazzi, G., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Magnetic Resonance in Medicine 88
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October 2022
Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
McGarvey, A.C., Kopp, W., Vučićević, D., Mattonet, K., Kempfer, R., Hirsekorn, A., Bilić, I., Gil, M., Trinks, A., Merks, A.M., Panáková, D., Pombo, A., Akalin, A., Junker, J.P., Stainier, D.Y.R., Garfield, D., Ohler, U. and Lacadie, S.A.
Cell Genomics 2
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13 January 2022
Physiological functions of intracellular protein degradation.
McShane, E. and Selbach, M.
Annual Review of Cell and Developmental Biology 38
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October 2022
Parametric MRI detects aristolochic acid induced acute kidney injury.
Mei, Y., Yang, G., Guo, Y., Zhao, K., Wu, S., Xu, Z., Zhou, S., Yan, C., Seeliger, E., Niendorf, T., Xu, Y. and Feng, Y.
Tomography 8
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10 December 2022
Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T., Lindemann, P., Welle, A., Trouillet, V., Heißler, S., Nazaré, M. and Selbach, M.
ChemMedChem 17
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6 October 2022
The genetic basis of Moyamoya disease.
Mertens, R., Graupera, M., Gerhardt, H., Bersano, A., Tournier-Lasserve, E., Mensah, M.A., Mundlos, S. and Vajkoczy, P.
Translational Stroke Research 13
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February 2022
Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its host.
Midha, A., Jarquín-Díaz, V.H., Ebner, F., Löber, U., Hayani, R., Kundik, A., Cardilli, A., Heitlinger, E., Forslund, S.K. and Hartmann, S.
Microbiome 10
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16 December 2022
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations.
Miller, T.E., Lareau, C.A., Verga, J.A., DePasquale, E.A.K., Liu, V., Ssozi, D., Sandor, K., Yin, Y., Ludwig, L.S., El Farran, C.A., Morgan, D.M., Satpathy, A.T., Griffin, G.K., Lane, A.A., Love, J.C., Bernstein, B.E., Sankaran, V.G. and van Galen, P.
Nature Biotechnology 40
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24 February 2022
Diet quality indices and gastrointestinal cancer risk: results from the Lifelines study.
Moazzen, S., Cortes-Ibañez, F.O., van der Vegt, B., Alizadeh, B.Z. and de Bock, G.H.
European Journal of Nutrition 61
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February 2022
Ferritin trajectories over repeated whole blood donations: results from the FIND+ study.
Moazzen, S., Sweegers, M.G., Janssen, M., Hogema, B.M., Hoekstra, T. and Van den Hurk, K.
Journal of Clinical Medicine 11
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1 July 2022
Hemodynamic stress-induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein.
Mohamed, B.A., Elkenani, M., Mobarak, S., Marques Rodrigues, D., Annamalai, K., Schnelle, M., Bader, M., Hasenfuss, G. and Toischer, K.
Journal of Cellular and Molecular Medicine 26
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August 2022
Targeting angiotensin type 2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice.
Mohammed, M., Johnson, D.N., Wang, L.A., Harden, S.W., Sheng, W., Spector, E.A., Elsaafien, K., Bader, M., Steckelings, U.M., Scott, K.A., Frazier, C.J., Sumners, C., Krause, E.G. and de Kloet, A.D.
Cardiovascular Research 118
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21 February 2022
Association of general and abdominal adiposity with postural changes in systolic blood pressure: results from the NAKO pretest and MetScan studies.
Moreno Velásquez, I., Jaeschke, L., Steinbrecher, A., Boeing, H., Keil, T., Janke, J. and Pischon, T.
Hypertension Research 45
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December 2022
Standardized annotation of translated open reading frames.
Mudge, J.M., Ruiz-Orera, J., Prensner, J.R., Brunet, M.A., Calvet, F., Jungreis, I., Gonzalez, Jo.M., Magrane, M., Martinez, T.F., Schulz, J.F., Yang, Y.T., Albà, M.M., Aspden, J.L., Baranov, P.V., Bazzini, A.A., Bruford, E., Martin, M.J., Calviello, L., Carvunis, A.R., Chen, J., Couso, J.P., Deutsch, E.W., Flicek, P., Frankish, A., Gerstein, M., Hubner, N., Ingolia, N.T., Kellis, M., Menschaert, G., Moritz, R.L., Ohler, U., Roucou, X., Saghatelian, A., Weissman, J.S. and van Heesch, S.
Nature Biotechnology 40
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July 2022
Characterization of critically ill patients with septic shock and sepsis-associated cardiomyopathy using cardiovascular MRI.
Muehlberg, F., Blaszczyk, E., Will, K., Wilczek, S., Brederlau, J. and Schulz-Menger, J.
ESC Heart Failure 9
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August 2022
Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus-specific.
Muehleman, D.L., Crocini, C., Swearingen, A.R., Ozeroff, C.D. and Leinwand, L.A.
American Journal of Physiology Heart and Circulatory Physiology 322
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May 2022
Severe heart failure in the setting of inflammatory cardiomyopathy with likely pathogenic titin variant.
Mueller, M., Zwinger, L., Klaassen, S., Poller, W., Monserrat Iglesias, L., Pablo Ochoa, J., Klingel, K., Landmesser, U. and Heidecker, B.
International Journal of Cardiology (IJC) Heart & Vasculature 39
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April 2022
Increased salt intake decreases diet-induced thermogenesis in healthy volunteers: a randomized placebo-controlled study.
Mähler, A., Klamer, S., Maifeld, A., Bartolomaeus, H., Markó, L., Chen, C.Y., Forslund, S.K., Boschmann, M., Müller, D.N. and Wilck, N.
Nutrients 14
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7 January 2022
In vivo skin regeneration and wound healing using cell micro-transplantation.
Nanić, L., Cedilak, A., Vidaček, N.Š., Gruber, F., Huzak, M., Bader, M. and Rubelj, I.
Pharmaceutics 14
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15 September 2022
Vascular and liver homeostasis in juvenile mice require endothelial cyclic AMP-dependent protein kinase A.
Nedvetsky, P.I., Cornelissen, I., Mathivet, T., Bouleti, C., Ou, P., Baatsen, P., Zhao, X., Schuit, F., Stanchi, F., Mostov, K.E. and Gerhardt, H.
International Journal of Molecular Sciences 23
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27 September 2022
USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer.
Nelson, J.K., Thin, M.Z., Evan, T., Howell, S., Wu, M., Almeida, B., Legrave, N., Koenis, D. S., Koifman, G., Sugimoto, Y., Llorian Sopena, M., MacRae, J., Nye, E., Howell, M., Snijders, A.P., Prachalias, A., Zen, Y., Sarker, D. and Behrens, A.
Nature Communications 13
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19 April 2022
Functional modulation of PTH1R activation and signaling by RAMP2.
Nemec, K., Schihada, H., Kleinau, G., Zabel, U., Grushevsky, E.O., Scheerer, P., Lohse, M.J. and Maiellaro, I.
Proceedings of the National Academy of Sciences of the United States of America 119
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9 August 2022
Mediterranean diet and atrial fibrillation: lessons learned from the AFHRI case-control study.
Neumann, F.A., Jagemann, B., Makarova, N., Börschel, C.S., Aarabi, G., Gutmann, F., Schnabel, R.B. and Zyriax, B.C.
Nutrients 14
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1 September 2022
Candesartan does not activate PPAR(γ) and its target genes in early gestation trophoblasts.
Neuper, L., Kummer, D., Forstner, D., Guettler, J., Ghaffari-Tabrizi-Wizsy, N., Fischer, C., Juch, H., Nonn, O. and Gauster, M.
International Journal of Molecular Sciences 23
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October 2022
IL11 activates pancreatic stellate cells and causes pancreatic inflammation, fibrosis and atrophy in a mouse model of pancreatitis.
Ng, B., Viswanathan, S., Widjaja, A.A., Lim, W.W., Shekeran, S.G., Goh, J.W.T., Tan, J., Kuthubudeen, F., Lim, S.Y., Xie, C., Schafer, S., Adami, E. and Cook, S.A.
International Journal of Molecular Sciences 23
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24 March 2022
Sizing up beta cells made from stem cells.
Nguyen-Ngoc, K.V., Wortham, M. and Sander, M.
Nature Biotechnology 40
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July 2022
Role of Gpnmb in atherosclerosis of female mice.
Nickl, B., Qadri, F. and Bader, M.
Biochemical and Biophysical Research Communications 621
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17 September 2022
Best practice standards for circular RNA research.
Nielsen, A.F., Bindereif, A., Bozzoni, I., Hanan, M., Hansen, T.B., Irimia, M., Kadener, S., Kristensen, L.S., Legnini, I., Morlando, M., Jarlstad Olesen, M.T., Pasterkamp, R.J., Preibisch, S., Rajewsky, N., Suenkel, C. and Kjems, J.
Nature Methods 19
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October 2022
Pre-diagnostic C-reactive protein concentrations, CRP genetic variation and mortality among individuals with colorectal cancer in Western European populations.
Nimptsch, K., Aleksandrova, K., Fedirko, V., Jenab, M., Gunter, M.J., Siersema, P.D., Wu, K., Katzke, V., Kaaks, R., Panico, S., Palli, D., May, A.M., Sieri, S., Bueno-de-Mesquita, B., Standahl, K., Sánchez, M.J., Perez-Cornago, A., Olsen, A., Tjønneland, A., Bonet, C.B., Dahm, C.C., Chirlaque, M.D., Fiano, V., Tumino, R., Barricarte Gurrea, A., Boutron-Ruault, M.C., Menegaux, F., Severi, G., van Guelpen, B., Lee, Y.A. and Pischon, T.
BMC Cancer 22
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24 June 2022
Epidemiologie der Adipositas.
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26 August 2022
Clinical features and natural history of preadolescent nonsyndromic hypertrophic cardiomyopathy.
Norrish, G., Cleary, A., Field, E., Cervi, E., Boleti, O., Ziółkowska, L., Olivotto, I., Khraiche, D., Limongelli, G., Anastasakis, A., Weintraub, R., Biagini, E., Ragni, L., Prendiville, T., Duignan, S., McLeod, K., Ilina, M., Fernandez, A., Marrone, C., Bökenkamp, R., Baban, A., Kubus, P., Daubeney, P.E.F., Sarquella-Brugada, G., Cesar, S., Klaassen, S., Ojala, T.H., Bhole, V., Medrano, C., Uzun, O., Brown, E., Gran, F., Sinagra, G., Castro, F.J., Stuart, G., Yamazawa, H., Barriales-Villa, R., Garcia-Guereta, L., Adwani, S., Linter, K., Bharucha, T., Gonzales-Lopez, E., Siles, A., Rasmussen, T.B., Calcagnino, M., Jones, C.B., De Wilde, H., Kubo, T., Felice, T., Popoiu, A., Mogensen, J., Mathur, S., Centeno, F., Reinhardt, Z., Schouvey, S., Elliott, P.M. and Kaski, J.P.
Journal of the American College of Cardiology 79
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24 May 2022
Relationship between maximal left ventricular wall thickness and sudden cardiac death in childhood onset hypertrophic cardiomyopathy.
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Circulation Arrhythmia and Electrophysiology 15
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May 2022
External validation of the HCM Risk-Kids model for predicting sudden cardiac death in childhood hypertrophic cardiomyopathy.
Norrish, G., Qu, C., Field, E., Cervi, E., Khraiche, D., Klaassen, S., Ojala, T.H., Sinagra, G., Yamazawa, H., Marrone, C., Popoiu, A., Centeno, F., Schouvey, S., Olivotto, I., Day, S.M., Colan, S., Rossano, J., Wittekind, S.G., Saberi, S., Russell, M., Helms, A., Ingles, J., Semsarian, C., Elliott, P.M., Ho, C.Y., Omar, R.Z. and Kaski, J.P.
European Journal of Preventive Cardiology 29
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30 March 2022
A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth.
Ong, Y.T., Andrade, J., Armbruster, M., Shi, C., Castro, M., Costa, A.S.H., Sugino, T., Eelen, G., Zimmermann, B., Wilhelm, K., Lim, J., Watanabe, S., Guenther, S., Schneider, A., Zanconato, F., Kaulich, M., Pan, D., Braun, T., Gerhardt, H., Efeyan, A., Carmeliet, P., Piccolo, S., Grosso, A.R. and Potente, M.
Nature Metabolism 4
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June 2022
Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla, T., Gollasch, B., Kuich, P.H.J.L., Klug, L., Rahn, G., Busjahn, A., Spuler, S., Boschmann, M., Kirwan, J.A., Luft, F.C. and Kempa, S.
Frontiers in Molecular Biosciences 9
: 1042231.
21 December 2022
Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.
Ortiz-Zapater, E., Bagley, D.C., Hernandez, V.L., Roberts, L.B., Maguire, T.J.A., Voss, F., Mertins, P., Kirchner, M., Peset-Martin, I., Woszczek, G., Rosenblatt, J., Gotthardt, M., Santis, G. and Parsons, M.
Nature Communications 13
(1): 6407.
27 October 2022
A computational model for prediction of ferritin and haemoglobin levels in blood donors.
Paalvast, Y., Moazzen, S., Sweegers, M., Hogema, B., Janssen, M. and van den Hurk, K.
British Journal of Haematology 199
(1): 143-152.
October 2022
Biosynthetic potential of the global ocean microbiome.
Paoli, L., Ruscheweyh, H.J., Forneris, C.C., Hubrich, F., Kautsar, S., Bhushan, A., Lotti, A., Clayssen, Q., Salazar, G., Milanese, A., Carlström, C.I., Papadopoulou, C., Gehrig, D., Karasikov, M., Mustafa, H., Larralde, M., Carroll, L.M., Sánchez, P., Zayed, A.A., Cronin, D.R., Acinas, S.G., Bork, P., Bowler, C., Delmont, T.O., Gasol, J.M., Gossert, A.D., Kahles, A., Sullivan, M.B., Wincker, P., Zeller, G., Robinson, S.L., Piel, J. and Sunagawa, S.
Nature 607
(7917): 111-118.
7 July 2022
Mitochondrial a kinase anchor proteins in cardiovascular health and disease: a review article on behalf of the Working Group on Cellular and Molecular Biology of the Heart of the Italian Society of Cardiology.
Paolillo, R., D’Apice, S., Schiattarella, G.G., Ameri, P., Borzacchiello, D., Catalucci, D., Chimenti, C., Crotti, L., Sciarretta, S., Torella, D., Feliciello, A. and Perrino, C.
International Journal of Molecular Sciences 23
(14): 7691.
12 July 2022
Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K., Leunig, A., Kaiser, R., Joppich, M., Brambs, S., Janjic, A., Popp, O., Nixdorf, D., Fumagalli, V., Schmidt, N., Polewka, V., Anjum, A., Knottenberg, V., Eivers, L., Wange, L.E., Gold, C., Kirchner, M., Muenchhoff, M., Hellmuth, J.C., Scherer, C., Rubio-Acero, R., Eser, T., Deák, F., Puchinger, K., Kuhl, N., Linder, A., Saar, K., Tomas, L., Schulz, C., Wieser, A., Enard, W., Kroidl, I., Geldmacher, C., von Bergwelt-Baildon, M., Keppler, O.T., Munschauer, M., Iannacone, M., Zimmer, R., Mertins, P., Hubner, N., Hoelscher, M., Massberg, S., Stark, K. and Nicolai, L.
Nature Communications 13
(1): 1018.
23 February 2022
Quantitative phosphoproteomics of the angiotensin AT(2)-receptor signaling network identifies HDAC1 (Histone-Deacetylase-1) and p53 as mediators of antiproliferation and apoptosis.
Peluso, A.A.B., Kempf, S.J., Verano-Braga, T., Rodrigues-Ribeiro, L., Johansen, L.E., Hansen, M.R., Kitlen, G., Haugaard, A.H., Sumners, C., Ditzel, H.J., Santos, R.A., Bader, M., Larsen, M.R. and Steckelings, U.M.
Hypertension 79
(11): 2530-2541.
November 2022
Formation and maintenance of the natural bypass vessels of the brain.
Perovic, T., Harms, C. and Gerhardt, H.
Frontiers in Cardiovascular Medicine 9
: 778773.
22 March 2022
Framework and baseline examination of the German National Cohort (NAKO).
Peters, A., Peters, A., Greiser, K.H., Göttlicher, S., Ahrens, W., Albrecht, M., Bamberg, F., Bärnighausen, T., Becher, H., Berger, K., Beule, A., Boeing, H., Bohn, B., Bohnert, K., Braun, B., Brenner, H., Bülow, R., Castell, S., Damms-Machado, A., Dörr, M., Ebert, N., Ecker, M., Emmel, C., Fischer, B., Franzke, C.W., Gastell, S., Giani, G., Günther, M., Günther, K., Günther, K.P., Haerting, J., Haug, U., Heid, I.M., Heier, M., Heinemeyer, D., Hendel, T., Herbolsheimer, F., Hirsch, J., Hoffmann, W., Holleczek, B., Hölling, H., Hörlein, A., Jöckel, K.H., Kaaks, R., Karch, A., Karrasch, S., Kartschmit, N., Kauczor, H.U., Keil, T., Kemmling, Y., Klee, B., Klüppelholz, B., Kluttig, A., Kofink, L., Köttgen, A., Kraft, D., Krause, G., Kretz, L., Krist, L., Kühnisch, J., Kuß, O., Legath, N., Lehnich, A.T., Leitzmann, M., Lieb, W., Linseisen, J., Loeffler, M., Macdonald, A., Maier-Hein, K.H., Mangold, N., Meinke-Franze, C., Meisinger, C., Melzer, J., Mergarten, B., Michels, K.B., Mikolajczyk, R., Moebus, S., Mueller, U., Nauck, M., Niendorf, T., Nikolaou, K., Obi, N., Ostrzinski, S., Panreck, L., Pigeot, I., Pischon, T., Pschibul-Thamm, I., Rathmann, W., Reineke, A., Roloff, S., Rujescu, D., Rupf, S., Sander, O., Schikowski, T., Schipf, S., Schirmacher, P., Schlett, C.L., Schmidt, B., Schmidt, G., Schmidt, M., Schöne, G., Schulz, H., Schulze, M.B., Schweig, A., Sedlmeier, A.M., Selder, S., Six-Merker, J., Sowade, R., Stang, A., Stegle, O., Steindorf, K., Stübs, G., Swart, E., Teismann, H., Thiele, I., Thierry, S., Ueffing, M., Völzke, H., Waniek, S., Weber, A., Werner, N., Wichmann, H.E., Willich, S.N., Wirkner, K., Wolf, K., Wolff, R., Zeeb, H., Zinkhan, M. and Zschocke, J.
European Journal of Epidemiology 37
(10): 1107-1124.
October 2022
Pre-diagnostic circulating resistin concentrations are not associated with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study.
Pham, T.T., Nimptsch, K., Aleksandrova, K., Jenab, M., Reichmann, R., Wu, K., Tjønneland, A., Kyrø, C., Schulze, M.B., Kaaks, R., Katzke, V., Palli, D., Pasanisi, F., Ricceri, F., Tumino, R., Krogh, V., Roodhart, J., Castilla, J., Sánchez, M.J., Colorado-Yohar, S.M., Harbs, J., Rutegård, M., Papier, K., Aglago, E.K., Dimou, N., Mayen-Chacon, A.L., Weiderpass, E. and Pischon, T.
Cancers 14
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9 November 2022
Nitric oxide metabolites: associations with cardiovascular biomarkers and clinical parameters in patients with HFpEF.
Piatek, K., Feuerstein, A., Zach, V., Rozados da Conceicao, C., Beblo, A., Belyavskiy, E., Pieske-Kraigher, E., Krannich, A., Schwedhelm, E., Hinz, S., Pieske, B. and Edelmann, F.
ESC Heart Failure 9
(6): 3961-3972.
December 2022
Tuning the 3D microenvironment of reprogrammed tubule cells enhances biomimetic modeling of polycystic kidney disease.
Pichler, R., Rizzo, L., Tröndle, K., Bühler, M., Brucker, H., Müller, A.L., Grand, K., Farè, S., Viau, A., Kaminski, M.M., Kuehn, E.W., Koch, F., Zimmermann, S., Koltay, P. and Lienkamp, S.S.
Biomaterials 291
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December 2022
Gut microbiome composition in obese and non-obese persons: a systematic review and meta-analysis.
Pinart, M., Dötsch, A., Schlicht, K., Laudes, M., Bouwman, J., Forslund, S.K., Pischon, T. and Nimptsch, K.
Nutrients 14
(1): 12.
1 January 2022
Cardiovascular magnetic resonance in children with suspected myocarditis: current practice and applicability of adult protocols.
Pitak, B., Opgen-Rhein, B., Schubert, S., Reineker, K., Wiegand, G., Boecker, D., Rentzsch, A., Ruf, B., Özcan, S., Wannenmacher, B., Pickardt, T., Seidel, F. and Messroghli, D.
Cardiology in the Young 32
(12): 1957-1965.
December 2022
EACVI survey on hypertrophic cardiomyopathy.
Podlesnikar, T., Cardim, N., Ajmone Marsan, N., D'Andrea, A., Cameli, M., Popescu, B.A., Schulz-Menger, J., Stankovic, I., Toplisek, J., Maurer, G., Haugaa, K.H. and Dweck, M.R.
European Heart Journal - Cardiovascular Imaging 23
(5): 590-597.
May 2022
Neuroligins in neurodevelopmental conditions: how mouse models of de novo mutations can help us link synaptic function to social behavior.
Pohl, T. and Hörnberg, H.
Neuronal Signaling 6
(2): NS20210030.
June 2022
Missense variant E1295K of sodium channel SCN5A associated with recurrent ventricular fibrillation and myocardial inflammation.
Poller, W., Escher, F., Haas, J., Heidecker, B., Schultheiss, H.P., Attanasio, P., Skurk, C., Haghikia, A., Meder, B. and Klaassen, S.
JACC: Case Reports 4
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2 March 2022
Long-term imaging reveals behavioral plasticity during C. elegans dauer exit.
Preusser, F., Neuschulz, A., Junker, J.P., Rajewsky, N. and Preibisch, S.
BMC Biology 20
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13 December 2022
Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics.
Pryszlak, A., Wenzel, T., Seitz, K.W., Hildebrand, F., Kartal, E., Cosenza, M.R., Benes, V., Bork, P. and Merten, C.A.
Cell Reports Methods 2
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24 January 2022
Sustainable low-field cardiovascular magnetic resonance in changing healthcare systems.
Qin, C., Murali, S., Lee, E., Supramaniam, V., Hausenloy, D.J., Obungoloch, J., Brecher, J., Lin, R., Ding, H., Akudjedu, T.N., Anazodo, U.C., Jagannathan, N.R., Ntusi, N.A.B., Simonetti, O.P., Campbell-Washburn, A.E., Niendorf, T., Mammen, R. and Adeleke, S.
European Heart Journal - Cardiovascular Imaging 23
(6): e246-e260.
1 June 2022
Radiofrequency antenna helmet array for thermal magnetic resonance of brain tumours at 297 MHz.
Rahimi, F., Berangi, M., Eigentler, T.W., Nurzed, B., Millward, J.M., Schuhmann, R. and Niendorf, T.
In: 2022 3rd URSI Atlantic and Asia Pacific Radio Science Meeting (AT-AP-RASC), 30 May - 04 Jun 2022, Gran Canaria, Spain.
6 July 2022
Systemic LSD1 inhibition prevents aberrant remodeling of metabolism in obesity.
Ramms, B., Pollow, D.P., Zhu, H., Nora, C., Harrington, A.R., Omar, I., Gordts, P.L.S.M., Wortham, M. and Sander, M.
Diabetes 71
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December 2022
A novel gene controls a new structure: piggyBac transposable element-derived 1, unique to mammals, controls mammal-specific neuronal paraspeckles.
Raskó, T., Pande, A., Radscheit, K., Zink, A., Singh, M., Sommer, C., Wachtl, G., Kolacsek, O., Inak, G., Szvetnik, A., Petrakis, S., Bunse, M., Bansal, V., Selbach, M., Orbán, T.I., Prigione, A., Hurst, L.D. and Izsvák, Z.
Molecular Biology and Evolution 39
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October 2022
Placental CD4(+) T cells from preeclamptic patients cause autoantibodies to the angiotensin II type I receptor and hypertension in a pregnant rat model of preeclampsia.
Reeve, K.E., Deer, E., Amaral, L.M., Cornelius, D.C., Herrock, O., Harmon, A.C., Campbell, N., Fitzgerald, S., Ibrahim, T., Wallukat, G., Dechend, R. and LaMarca, B.
Exploration of Medicine 3
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25 February 2022
Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies.
Reichart, D., Lindberg, E.L., Maatz, H., Miranda, A.M.A., Viveiros, A., Shvetsov, N., Gärtner, A., Nadelmann, E.R., Lee, M., Kanemaru, K., Ruiz-Orera, J., Strohmenger, V., DeLaughter, D.M., Patone, G., Zhang, H., Woehler, A., Lippert, C., Kim, Y., Adami, E., Gorham, J.M., Barnett, S.N., Brown, K., Buchan, R.J., Chowdhury, R.A., Constantinou, C., Cranley, J., Felkin, L.E., Fox, H., Ghauri, A., Gummert, J., Kanda, M., Li, R., Mach, L., McDonough, B., Samari, S., Shahriaran, F., Yapp, C., Stanasiuk, C., Theotokis, P.I., Theis, F.J., van den Bogaerdt, A., Wakimoto, H., Ware, J.S., Worth, C.L., Barton, P.J.R., Lee, Y.A., Teichmann, S.A., Milting, H., Noseda, M., Oudit, G.Y., Heinig, M., Seidman, J.G., Hubner, N. and Seidman, C.E.
Science 377
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5 August 2022
Occupation and SARS-CoV-2 infection risk among 108 960 workers during the first pandemic wave in Germany.
Reuter, M., Rigó, M., Formazin, M., Liebers, F., Latza, U., Castell, S., Jöckel, K.H., Greiser, K.H., Michels, K.B., Krause, G., Albrecht, S., Öztürk, I., Kuss, O., Berger, K., Lampl, B.M.J., Leitzmann, M., Zeeb, H., Starke, K.R., Schipf, S., Meinke-Franze, C., Ahrens, W., Seidler, A., Klee, B., Pischon, T., Deckert, A., Schmidt, B., Mikolajczyk, R., Karch, A., Bohn, B., Brenner, H., Holleczek, B. and Dragano, N.
Scandinavian Journal of Work Environment & Health 48
(9): 446-456.
1 September 2022
Mental and behavioural responses to Bahá'í fasting: looking behind the scenes of a religiously motivated intermittent fast using a mixed methods approach.
Ring, R.M., Eisenmann, C., Kandil, F.I., Steckhan, N., Demmrich, S., Klatte, C., Kessler, C.S., Jeitler, M., Boschmann, M., Michalsen, A., Blakeslee, S.B., Stöckigt, B., Stritter, W. and Koppold-Liebscher, D.A.
Nutrients 14
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28 February 2022
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes.
Ringel, A.R., Szabo, Q., Chiariello, A.M., Chudzik, K., Schöpflin, R., Rothe, P., Mattei, A.L., Zehnder, T., Harnett, D., Laupert, V., Bianco, S., Hetzel, S., Glaser, J., Phan, M.H.Q., Schindler, M., Ibrahim, D.M., Paliou, C., Esposito, A., Prada-Medina, C.A., Haas, S.A., Giere, P., Vingron, M., Wittler, L., Meissner, A., Nicodemi, M., Cavalli, G., Bantignies, F., Mundlos, S. and Robson, M.I.
Cell 185
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29 September 2022
Development of an indole-amide-based photoswitchable cannabinoid receptor subtype 1 (CB(1)R) "Cis-On" agonist.
Rodríguez-Soacha, D.A., Steinmüller, S.A.M., Işbilir, A., Fender, J., Deventer, M.H., Ramírez, Y.A., Tutov, A., Sotriffer, C., Stove, C.P., Lorenz, K., Lohse, M.J., Hislop, J.N. and Decker, M.
ACS Chemical Neuroscience 13
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17 August 2022
WASp controls oriented migration of endothelial cells to achieve functional vascular patterning.
Rosa, A., Giese, W., Meier, K., Alt, S., Klaus-Bergmann, A., Edgar, L.T., Bartels, E., Collins, R., Szymborska, A., Coxam, B., Bernabeu, M.O. and Gerhardt, H.
Development 149
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February 2022
CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Rousselle, A., Sonnemann, J., Amann, K., Mildner, A., Lodka, D., Kling, L., Bieringer, M., Schneider, U., Leutz, A., Enghard, P., Kettritz, R. and Schreiber, A.
Annals of the Rheumatic Diseases 81
(8): 1162-1172.
August 2022
Cultivation-independent genomes greatly expand taxonomic-profiling capabilities of mOTUs across various environments.
Ruscheweyh, H.J., Milanese, A., Paoli, L., Karcher, N., Clayssen, Q., Keller, M.I., Wirbel, J., Bork, P., Mende, D.R., Zeller, G. and Sunagawa, S.
Microbiome 10
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5 December 2022
Diagnostic accuracy of cerebrospinal fluid biomarkers for the differential diagnosis of sporadic Creutzfeldt-Jakob disease: a (network) meta-analysis.
Rübsamen, N., Pape, S., Konigorski, S., Zapf, A., Rücker, G. and Karch, A.
European Journal of Neurology 29
(5): 1366-1376.
May 2022
Machine learning evaluation of LV outflow obstruction in hypertrophic cardiomyopathy using three-chamber cardiovascular magnetic resonance.
Sahota, M., Saraskani, S.R., Xu, H., Li, L., Majeed, A.W., Hermida, U., Neubauer, S., Desai, M., Weintraub, W., Desvigne-Nickens, P., Schulz-Menger, J., Kwong, R.Y., Kramer, C.M., Young, A.A. and Lamata, P.
International Journal of Cardiovascular Imaging 38
(12): 2695-2705.
December 2022
Epigenetic targeting of transposon relics: beating the dead horses of the genome?
Sammarco, I., Pieters, J., Salony, S., Toman, I., Zolotarov, G. and Lafon Placette, C.
Epigenetics 17
(11): 1331-1344.
November 2022
Peripheral serotonin deficiency affects anxiety-like behavior and the molecular response to an acute challenge in rats.
Sbrini, G., Hanswijk, S.I., Brivio, P., Middelman, A., Bader, M., Fumagalli, F., Alenina, N., Homberg, J.R. and Calabrese, F.
International Journal of Molecular Sciences 23
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29 April 2022
Stroke-heart syndrome: recent advances and challenges.
Scheitz, J.F., Sposato, L.A., Schulz-Menger, J., Nolte, C.H., Backs, J. and Endres, M.
Journal of the American Heart Association 11
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6 September 2022
Immunometabolic mechanisms of heart failure with preserved ejection fraction.
Schiattarella, G.G., Alcaide, P., Condorelli, G., Gillette, T.G., Heymans, S., Jones, E.A.V., Kallikourdis, M., Lichtman, A., Marelli-Berg, F., Shah, S.J., Thorp, E.B. and Hill, J.A.
Nature Cardiovascular Research 1
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March 2022
Hypo- und Hypernatriämien auf der Intensivstation : Fallstricke des Volumenmanagements [Hypo- and hypernatremia in the intensive care unit : pitfalls in volume management].
Schilling, J., Compton, F. and Schmidt-Ott, K.
Wiener klinisches Magazin 25
: 32-37.
10 January 2022
Dissecting the intracellular pancreatic tumor microbiome at single-cell level.
Schmidt, T.S.B. and Bork, P.
Cancer Cell 40
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10 October 2022
Drivers and determinants of strain dynamics following fecal microbiota transplantation.
Schmidt, T.S.B., Li, S.S., Maistrenko, O.M., Akanni, W., Coelho, L.P., Dolai, S., Fullam, A., Glazek, A.M., Hercog, R., Herrema, H., Jung, F., Kandels, S., Orakov, A., Thielemann, R., von Stetten, M., Van Rossum, T., Benes, V., Borody, T.J., de Vos, W.M., Ponsioen, C.Y., Nieuwdorp, M. and Bork, P.
Nature Medicine 28
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September 2022
Prävention des akuten Nierenversagens [Prevention of acute kidney injury].
Schmidt-Ott, K.M. and Swolinsky, J.
Deutsche Medizinische Wochenschrift 147
(5): 236-245.
March 2022
Tailoring cardiac synthetic transcriptional modulation towards precision medicine.
Schoger, E., Lelek, S., Panáková, D. and Zelarayán, L.C.
Frontiers in Cardiovascular Medicine 8
: 783072.
14 January 2022
In prostate cancer cells cytokines are early responders to gravitational changes occurring in parabolic flights.
Schulz, H., Dietrichs, D., Wehland, M., Corydon, T.J., Hemmersbach, R., Liemersdorf, C., Melnik, D., Hübner, N., Saar, K., Infanger, M. and Grimm, D.
International Journal of Molecular Sciences 23
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17 July 2022
SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F., de Castro Cuadrat, R.R., Wyler, E., Wurmus, R., Deter, A., Quedenau, C., Dohmen, J., Faxel, M., Borodina, T., Blume, A., Freimuth, J., Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B., Franke, V., Barke, N., Altmüller, J., Rajewsky, N., Landthaler, M. and Akalin, A.
Science of the Total Environment 853
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20 December 2022
Whole-body magnetic resonance imaging in the large population-based German National Cohort study: predictive capability of automated image quality assessment for protocol repetitions.
Schuppert, C., von Krüchten, R., Hirsch, J.G., Rospleszcz, S., Hoinkiss, D.C., Selder, S., Köhn, A., von Stackelberg, O., Peters, A., Völzke, H., Kröncke, T., Niendorf, T., Forsting, M., Hosten, N., Hendel, T., Pischon, T., Jöckel, K.H., Kaaks, R., Bamberg, F., Kauczor, H.U., Günther, M. and Schlett, C.L.
Investigative Radiology 57
(7): 478-487.
1 July 2022
On the relation between input and output distributions of scRNA-seq experiments.
Schwabe, D. and Falcke, M.
Bioinformatics 38
(5): 1336-1343.
1 March 2022
Eating patterns during pregnancy and postpartum and their association with diet quality and energy intake.
Schwedhelm, C., Lipsky, L.M., Temmen, C.D. and Nansel, T.R.
Nutrients 14
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10 March 2022
3D-printed tissue-simulating phantoms for near-infrared fluorescence imaging of rheumatoid diseases.
Schädel-Ebner, S., Hirsch, O., Gladytz, T., Gutkelch, D., Licha, K., Berger, J. and Grosenick, D.
Journal of Biomedical Optics 27
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July 2022
Highly conserved interaction profiles between clinically relevant mutants of the cytomegalovirus CDK-like kinase pUL97 and human cyclins: functional significance of cyclin H.
Schütz, M., Müller, R., Socher, E., Wangen, C., Full, F., Wyler, E., Wong, D., Scherer, M., Stamminger, T., Chou, S., Rawlinson, W.D., Hamilton, S.T., Sticht, H. and Marschall, M.
International Journal of Molecular Sciences 23
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5 October 2022
Evaluation of lake sedimentary ancient DNA metabarcoding to assess fungal biodiversity in Arctic paleoecosystems.
Seeber, P.A., Hippel, B., Kauserud, H., Löber, U., Stoof‐Leichsenring, K.R., Herzschuh, U. and Epp, L.S.
Environmental DNA 4
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September 2022
Pathogenic variants in cardiomyopathy disorder genes underlie pediatric myocarditis - Further impact of heterozygous immune disorder gene variants?
Seidel, F., Laser, K.T., Klingel, K., Dartsch, J., Theisen, S., Pickardt, T., Holtgrewe, M., Gärtner, A., Berger, F., Beule, D., Milting, H., Schubert, S., Klaassen, S. and Kühnisch, J.
Journal of Cardiovascular Development and Disease 9
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5 July 2022
Clinical characteristics and outcome of biopsy-proven myocarditis in children - Results of the German prospective multicentre registry "MYKKE".
Seidel, F., Opgen-Rhein, B., Rentzsch, A., Boehne, M., Wannenmacher, B., Boecker, D., Reineker, K., Grafmann, M., Wiegand, G., Hecht, T., Kiski, D., Fischer, M., Papakostas, K., Ruf, B., Kramp, J., Khalil, M., Kaestner, M., Steinmetz, M., Fischer, G., Özcan, S., Freudenthal, N., Schweigmann, U., Hellwig, R., Pickardt, T., Klingel, K., Messroghli, D. and Schubert, S.
International Journal of Cardiology 357
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15 June 2022
Compensatory upregulation of anti-beta-adrenergic receptor antibody levels might prevent heart failure presentation in pediatric myocarditis.
Seidel, F., Scheibenbogen, C., Heidecke, H., Opgen-Rhein, B., Pickardt, T., Klingel, K., Berger, F., Messroghli, D. and Schubert, S.
Frontiers in Pediatrics 10
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28 April 2022
Optocoder: computational decoding of spatially indexed bead arrays.
Senel, E., Rajewsky, N. and Karaiskos, N.
NAR Genomics and Bioinformatics 4
(2): lqac042.
June 2022
SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition.
Shih, A.Z.L., Chen, Y.C., Speckmann, T., Søndergaard, E., Schürmann, A., Verchere, C.B. and Willnow, T.E.
Molecular Metabolism 65
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November 2022
Amelioration of endotoxemia by a synthetic analog of Omega-3 epoxyeicosanoids.
Shikuma, A., Kami, D., Maeda, R., Suzuki, Y., Sano, A., Taya, T., Ogata, T., Konkel, A., Matoba, S., Schunck, W.H. and Gojo, S.
Frontiers in Immunology 13
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24 February 2022
Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.
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6 December 2022
Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
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Journal of Medicinal Chemistry 65
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25 August 2022
Why angiotensin II is a poor choice for circulatory support of ventilated COVID-19 patients compared to vasopressin.
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Medical Research Archives 10
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September 2022
Nationwide registry-based analysis of infective endocarditis risk after pulmonary valve replacement.
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18 February 2022
Lifetime and current depression in the German National Cohort (NAKO).
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World Journal of Biological Psychiatry 24
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17 February 2022
Cell type diversity in a developing octopus brain.
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Nature Communications 13
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30 November 2022
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer.
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Nature Structural & Molecular Biology 29
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September 2022
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July 2022
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February 2022
Skeletal muscle derived Musclin protects the heart during pathological overload.
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10 January 2022
Spacemake: processing and analysis of large-scale spatial transcriptomics data.
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19 July 2022
Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease.
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Nature Medicine 28
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Birth order, caesarean section, or daycare attendance in relation to child- and adult-onset type 1 diabetes: results from the german national cohort.
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31 August 2022
Pharmacological inhibition of adipose tissue Adipose Triglyceride Lipase (ATGL) by Atglistatin prevents catecholamine-induced myocardial damage.
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Genetic engineering of lymphangiogenesis in skin does not affect blood pressure in mouse models of salt-sensitive hypertension.
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MicroRNAs are deeply linked to the emergence of the complex octopus brain.
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1 March 2021
STEM pride: perspectives from transgender, nonbinary, and genderqueer scientists.
Armada-Moreira, A., Cizauskas, C., Fleury, G., Forslund, S.K., Guthman, E.M., Hanafiah, A., Hope, J.M., Jayasinghe, I., McSweeney, D. and Young, I.D.
Cell 184
(13): 3352-3355.
24 June 2021
ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling.
Asaro, A., Sinha, R., Bakun, M., Kalnytska, O., Carlo-Spiewok, A.S., Rubel, T., Rozeboom, A., Dadlez, M., Kaminska, B., Aronica, E., Malik, A.R. and Willnow, T.E.
Journal of Cell Science 134
(20): jcs258894.
15 October 2021
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C., Mouktaroudi, M., Krämer, B., Oestreich, M., Antonakos, N., Nuesch-Germano, M., Gkizeli, K., Bonaguro, L., Reusch, N., Baßler, K., Saridaki, M., Knoll, R., Pecht, T., Kapellos, T.S., Doulou, S., Kröger, C., Herbert, M., Holsten, L., Horne, A., Gemünd, I.D., Rovina, N., Agrawal, S., Dahm, K., van Uelft, M., Drews, A., Lenkeit, L., Bruse, N., Gerretsen, J., Gierlich, J., Becker, M., Händler, K., Kraut, M., Theis, H., Mengiste, S., Domenico, E., Schulte-Schrepping, J., Seep, L., Raabe, J., Hoffmeister, C., ToVinh, M., Keitel, V., Rieke, G., Talevi, V., Skowasch, D., Aziz, N.A., Pickkers, P., van de Veerdonk, F.L., Netea, M.G., Schultze, J.L., Kox, M., Breteler, M.M.B., Nattermann, J., Koutsoukou, A., Giamarellos-Bourboulis, E.J. and Ulas, T.
Genome Medicine 13
(1): 7.
13 January 2021
Acceleration of TAA-induced liver fibrosis by stress exposure is associated with upregulation of nerve growth factor and glycopattern deviations.
Atorrasagasti, C., Piccioni, F., Borowski, S., Tirado-González, I., Freitag, N., Cantero, M.J., Bayo, J., Mazzolini, G., Alaniz, L.D., Blois, S.M. and Garcia, M.G.
International Journal of Molecular Sciences 22
(10): 5055.
11 May 2021
Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease.
Audain, E., Wilsdon, A., Breckpot, J., Izarzugaza, J.M., Fitzgerald, T.W., Kahlert, A.K., Sifrim, A., Wünnemann, F., Perez-Riverol, Y., Abdul-Khaliq, H., Bak, M., Bassett, A.S., Benson, W.D., Berger, F., Daehnert, I., Devriendt, K., Dittrich, S., Daubeney, P.E., Garg, V., Hackmann, K., Hoff, K., Hofmann, P., Dombrowsky, G., Pickardt, T., Bauer, U., Keavney, B.D., Klaassen, S., Kramer, H.H., Marshall, C.R., Milewicz, D.M., Lemaire, S., Coselli, J.S., Mitchell, M.E., Tomita-Mitchell, A., Prakash, S.K., Stamm, K., Stewart, A.F.R., Silversides, C.K., Siebert, R., Stiller, B., Rosenfeld, J.A., Vater, I., Postma, A.V., Caliebe, A., Brook, J.D., Andelfinger, G., Hurles, M.E., Thienpont, B., Larsen, L.A. and Hitz, M.P.
PLoS Genetics 17
(7): e1009679.
29 July 2021
The gut microbiome in hypertension: recent advances and future perspectives.
Avery, E.G., Bartolomaeus, H., Maifeld, A., Marko, L., Wiig, H., Wilck, N., Rosshart, S.P., Forslund, S.K. and Muller, D.N.
Circulation Research 128
(7): 934-950.
2 April 2021
Renin-angiotensin-aldosterone system.
Bader, M.
In:
Encyclopedia of Molecular Pharmacology : Third Edition.
Springer, Cham, 1353-1358.
ISBN 978-3-030-57400-0
2021
Metagenomic assessment of the global diversity and distribution of bacteria and fungi.
Bahram, M., Netherway, T., Frioux, C., Ferretti, P., Coelho, L.P., Geisen, S., Bork, P. and Hildebrand, F.
Environmental Microbiology 23
(1): 316-326.
January 2021
Vasopressin-vermittelte Wasserrückresorption im Sammelrohr der Niere [Vasopressin-mediated water reabsorption in the renal collecting duct].
Baltzer, S. and Klussmann, E.
BIOspektrum 27
(2): 165-167.
March 2021
Extracellular matrix in heart Failure: role of ADAMTS5 in proteoglycan remodeling.
Barallobre-Barreiro, J., Radovits, T., Fava, M., Mayr, U., Lin, W.Y., Ermolaeva, E., Martínez-López, D., Lindberg, E.L., Duregotti, E., Daróczi, L., Hasman, M., Schmidt, L.E., Singh, B., Lu, R., Baig, F., Siedlar, A.M., Cuello, F., Catibog, N., Theofilatos, K., Shah, A.M., Crespo-Leiro, M.G., Doménech, N., Hübner, N., Merkely, B. and Mayr, M.
Circulation 144
(25): 2021-2034.
21 December 2021
Quantifying technical confounders in microbiome studies.
Bartolomaeus, T.U.P., Birkner, T., Bartolomaeus, H., Löber, U., Avery, E.G., Mähler, A., Weber, D., Kochlik, B., Balogh, A., Wilck, N., Boschmann, M., Müller, D.N., Markó, L. and Forslund, S.K.
Cardiovascular Research 117
(3): 863-875.
1 March 2021
Isolation, culture, and genetic engineering of mammalian primary pigment epithelial cells for non-viral gene therapy.
Bascuas, T., Kropp, M., Harmening, N., Wong, B.M., Johnen, S., Izsvák, Z. and Thumann, G.
Journal of Visualized Experiments
(168): e62145.
26 February 2021
Vasohibin-1 selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk.
Bastos de Oliveira, M., Meier, K., Jung, S., Bartels-Klein, E., Coxam, B., Geudens, I., Szymborska, A., Skoczylas, R., Fechner, I., Koltowska, K. and Gerhardt, H.
Development 148
(4): dev194993.
19 February 2021
Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes.
Bathe-Peters, M., Gmach, P., Boltz, H.H., Einsiedel, J., Gotthardt, M., Hübner, H., Gmeiner, P., Lohse, M.J. and Annibale, P.
Proceedings of the National Academy of Sciences of the United States of America 118
(23): e2101119118.
8 June 2021
A backward-mode optical-resolution photoacoustic microscope for 3D imaging using a planar Fabry-Pérot sensor.
Baumann, E., Pohle, U., Zhang, E., Allen, T., Villringer, C., Pulwer, S., Gerhardt, H. and Laufer, J.
Photoacoustics 24
: 100293.
December 2021
Protein intake, metabolic status and the gut microbiota in different ethnicities: results from two independent cohorts.
Bel Lassen, P., Attaye, I., Adriouch, S., Nicolaou, M., Aron-Wisnewsky, J., Nielsen, T., Chakaroun, R., Le Chatelier, E., Forslund, S., Belda, E., Bork, P., Bäckhed, F., Stumvoll, M., Pedersen, O., Herrema, H., Groen, A., Pinto-Sietsma, S.J., Zwinderman, A., Nieuwdorp, M. and Clement, K.
Nutrients 13
(9): 3159.
September 2021
Viewpoints on the first transatlantic GPCR symposium for early-career investigators.
Bender, B.J., Bock, A., Nesheva, D.N. and Perry-Hauser, N.A.
ACS Pharmacology & Translational Science 4
(5): 1705-1711.
8 October 2021
Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort.
Birukov, A., Andersen, L.B., Andersen, M.S., Nielsen, J.H., Nielsen, F.g, Kyhl, H.B., Jørgensen, J.S., Grandjean, P., Dechend, R. and Jensen, T.K.
Environment International 151
: 106442.
June 2021
Role of CMR imaging in diagnostics and evaluation of cardiac involvement in muscle dystrophies.
Blaszczyk, E., Gröschel, J. and Schulz-Menger, J.
Current Heart Failure Reports 18
(4): 211-224.
August 2021
Progressive myocardial injury in myotonic dystrophy type II and facioscapulohumeral muscular dystrophy 1: a cardiovascular magnetic resonance follow-up study.
Blaszczyk, E., Lim, C., Kellman, P., Schmacht, L., Gröschel, J., Spuler, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 23
(1): 130.
8 November 2021
Uncovering de novo gene birth in yeast using deep transcriptomics.
Blevins, W.R., Ruiz-Orera, J., Messeguer, X., Blasco-Moreno, B., Villanueva-Cañas, J.L., Espinar, L., Díez, J., Carey, L.B. and Albà, M.M.
Nature Communications 12
(1): 604.
27 January 2021
Placental glycoredox dysregulation associated with disease progression in an animal model of superimposed preeclampsia.
Blois, S.M., Prince, P.D., Borowski, S., Galleano, M. and Barrientos, G.
Cells 10
(4): 800.
April 2021
Transverse aortic constriction induces gut barrier alterations, microbiota remodeling and systemic inflammation.
Boccella, N., Paolillo, R., Coretti, L., D'Apice, S., Lama, A., Giugliano, G., Schiattarella, G.G., Cuomo, M., d'Aquino, I., Cavaliere, G., Paciello, O., Mollica, M.P., Mattace Raso, G., Esposito, G., Lembo, F. and Perrino, C.
Scientific Reports 11
(1): 7404.
1 April 2021
Allosteric coupling and biased agonism in G protein-coupled receptors.
Bock, A. and Bermudez, M.
FEBS Journal 288
(8): 2513-2528.
April 2021
Implications of SGLT inhibition on redox signalling in atrial fibrillation.
Bode, D., Semmler, L., Oeing, C.U., Alogna, A., Schiattarella, G.G., Pieske, B.M., Heinzel, F.R. and Hohendanner, F.
International Journal of Molecular Sciences 22
(11): 5937.
31 May 2021
Phenotyping placental oxygenation in Lgals1 deficient mice using (19)F MRI.
Boehm-Sturm, P., Mueller, S., Freitag, N., Borowski, S., Foddis, M., Koch, S.P., Temme, S., Flögel, U. and Blois, S.M.
Scientific Reports 11
(1): 2126.
22 January 2021
Quantitative spectroscopy of single molecule interaction times.
Boltz, H.H., Sirbu, A., Stelzer, N., Lohse, M.J., Schütte, C. and Annibale, P.
Optics Letters 46
(7): 1538-1541.
1 April 2021
Methodology of measuring postoperative cognitive dysfunction: a systematic review.
Borchers, F., Spies, C.D., Feinkohl, I., Brockhaus, W.R., Kraft, A., Kozma, P., Fislage, M., Kühn, S., Ionescu, C., Speidel, S., Hadzidiakos, D., Veldhuijzen, D.S., Yürek, F., Evered, L.A. and Ottens, T.H.
British Journal of Anaesthesia 126
(6): 1119-1127.
June 2021
The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons.
Borroto-Escuela, D.O., Ferraro, L., Beggiato, S., Narváez, M., Fores-Pons, R., Alvarez-Contino, J.E., Wydra, K., Frankowska, M., Bader, M., Filip, M. and Fuxe, K.
Pharmacological Reports 73
(4): 1096-1108.
August 2021
Human and preclinical studies of the host-gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health.
Brial, F., Chilloux, J., Nielsen, T., Vieira-Silva, S., Falony, G., Andrikopoulos, P., Olanipekun, M., Hoyles, L., Djouadi, F., Neves, A.L., Rodriguez-Martinez, A., Mouawad, G.I., Pons, N., Forslund, S., Le-Chatelier, E., Le Lay, A., Nicholson, J., Hansen, T., Hyötyläinen, T., Clément, K., Oresic, M., Bork, P., Ehrlich, S.D., Raes, J., Pedersen, O.B., Gauguier, D. and Dumas, M.E.
Gut 70
(11): 2105-2114.
7 October 2021
Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M., Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M., Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A., Scheidereit, C., Butter, C., Felix, S.B., Otto, O., Luft, F.C., Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12
(6): 1653-1668.
December 2021
Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca(2+) entry after pressure-overload induced cardiac remodelling.
Camacho Londoño, J.E., Kuryshev, V., Zorn, M., Saar, K., Tian, Q., Hübner, N., Nawroth, P., Dietrich, A., Birnbaumer, L., Lipp, P., Dieterich, C. and Freichel, M.
Progress in Biophysics and Molecular Biology 159
: 86-104.
January 2021
Quantitative assessment of renal perfusion and oxygenation by invasive probes: basic concepts.
Cantow, K., Evans, R.G., Grosenick, D., Gladytz, T., Niendorf, T., Flemming, B. and Seeliger, E.
Methods in Molecular Biology 2216
: 89-107.
2021
Monitoring renal hemodynamics and oxygenation by invasive probes: experimental protocol.
Cantow, K., Ladwig-Wiegard, M., Flemming, B., Pohlmann, A., Niendorf, T. and Seeliger, E.
Methods in Molecular Biology 2216
: 327-347.
2021
Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ.
Cappelletti, V., Hauser, T., Piazza, I., Pepelnjak, M., Malinovska, L., Fuhrer, T., Li, Y., Dörig, C., Boersema, P., Gillet, L., Grossbac