Cardiac MRI in small animals

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Item Type:	Article
Title:	Cardiac MRI in small animals
Creators:	Ku, M.C. ORCID: https://orcid.org/0000-0003-0963-2461, Huelnhagen, T. ORCID: https://orcid.org/0000-0002-6755-2171, Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527 and Pohlmann, A. ORCID: https://orcid.org/0000-0002-8572-2568
Abstract:	Cardiac magnetic resonance (MR) imaging of mice is a valuable tool for the precise in vivo diagnosis and prognosis of heart defects. This detailed protocol describes the method of cardiac MR imaging in mice step by step. A series of MR images captures the contractile function of the mouse heart and post-processing of the image data yields morphometric parameters (myocardial mass, myocardial wall thickness, ventricular end-systolic and end-diastolic volume) as well as functional parameters (stroke volume and ejection fraction). This protocol may also serve as a starting point for MR imaging of rats, by using larger image dimensions (field-of-view) and MR hardware suitable for larger animals.
Keywords:	Magnetic Resonance Imaging (MRI), Cardiac Magnetic Resonance Imaging (CMR), Heart, Function, Animals, Mice, Rats
Source:	Methods in Molecular Biology
Series Name:	Methods in Molecular Biology
Title of Book:	Preclinical MRI
ISSN:	1064-3745
ISBN:	978-1-4939-7530-3
Publisher:	Springer / Humana Press
Volume:	1718
Page Range:	269-284
Date:	2018
Official Publication:	https://doi.org/10.1007/978-1-4939-7531-0_16
PubMed:	View item in PubMed

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