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Cardiac MRI in small animals

Item Type:Article
Title:Cardiac MRI in small animals
Creators Name:Ku, M.C., Huelnhagen, T., Niendorf, T. and Pohlmann, A.
Abstract:Cardiac magnetic resonance (MR) imaging of mice is a valuable tool for the precise in vivo diagnosis and prognosis of heart defects. This detailed protocol describes the method of cardiac MR imaging in mice step by step. A series of MR images captures the contractile function of the mouse heart and post-processing of the image data yields morphometric parameters (myocardial mass, myocardial wall thickness, ventricular end-systolic and end-diastolic volume) as well as functional parameters (stroke volume and ejection fraction). This protocol may also serve as a starting point for MR imaging of rats, by using larger image dimensions (field-of-view) and MR hardware suitable for larger animals.
Keywords:Magnetic Resonance Imaging (MRI), Cardiac Magnetic Resonance Imaging (CMR), Heart, Function, Animals, Mice, Rats
Source:Methods in Molecular Biology
Series Name:Methods in Molecular Biology
Title of Book:Preclinical MRI
Publisher:Springer / Humana Press
Page Range:269-284
Official Publication:https://doi.org/10.1007/978-1-4939-7531-0_16
PubMed:View item in PubMed

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