Helmholtz Gemeinschaft

Search
Browse
Statistics
Feeds

High Impact Publications (Impact Factor > 10)

Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Date | Item Type | Divisions
Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992

2024

Intranasal delivery of low-dose anti-CD124 antibody enhances treatment of chronic rhinosinusitis with nasal polyps.
Wu, J. and Jones, N. and Chao, P.H. and Chan, V. and Hohenwarter, L. and Wu, A. and Bergamo, M. and Rodríguez-Rodríguez, C. and Saatchi, K. and Liang, A. and Häfeli, U.O. and Tan, Z. and Hedtrich, S. and Andrew, L.J. and Li, S.D.
Biomaterials 308 : 122567. July 2024

Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells.
Chiariello, A.M. and Abraham, Alex and Bianco, S. and Esposito, A. and Fontana, A. and Vercellone, F. and Conte, M. and Nicodemi, M.
Nature Communications 15 (1): 4014. 13 May 2024

The diversity of the microbiome impacts chronic lymphocytic leukemia development in mice and humans.
Faitova, T. and Coelho, M. and Da Cunha-Bang, C. and Ozturk, S. and Kartal, E. and Bork, P. and Seiffert, M. and Niemann, C.U.
Haematologica 9 May 2024 (In Press)

Complete male-to-female sex reversal in XY mice lacking the miR-17~92 cluster.
Hurtado, A. and Mota-Gómez, I. and Lao, M. and Real, F.M. and Jedamzick, J. and Burgos, M. and Lupiáñez, D.G. and Jiménez, R. and Barrionuevo, F.J.
Nature Communications 15 (1): 3809. 7 May 2024

Tackling metabolic defects in HFpEF.
Wang, R. and Schiattarella, G.G.
European Heart Journal 45 (17): 1494-1496. 1 May 2024

Next questions in autophagy.
Cuervo, A.M. and Elazar, Z. and Evans, C. and Ge, L. and Hansen, M. and Jäättelä, M. and Liang, J.R.A. and Loos, B. and Mizushima, N. and Simon, A.K. and Tooze, S. and Yoshimori, T. and Nakamura, S.
Nature Cell Biology 26 (5): 661-666. May 2024

Modular segmentation, spatial analysis and visualization of volume electron microscopy datasets.
Müller, A. and Schmidt, D. and Albrecht, J.P. and Rieckert, L. and Otto, M. and Galicia Garcia, L.E. and Fabig, G. and Solimena, M. and Weigert, M.
Nature Protocols 19 (5): 1436-1466. May 2024

Neighborhood-level inequalities and influencing factors of COVID-19 incidence in berlin based on Bayesian spatial modelling.
Zhuang, S. and Wolf, K. and Schmitz, T. and Roth, A. and Sun, Y. and Savaskan, N. and Lakes, T.
Sustainable Cities and Society 104 : 105301. May 2024

Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish.
Cardeira-da-Silva, J. and Wang, Q. and Sagvekar, P. and Mintcheva, J. and Latting, S. and Günther, S. and Ramadass, R. and Yekelchyk, M. and Preussner, J. and Looso, M. and Junker, J.P. and Stainier, D.Y.R.
Nature Communications 15 (1): 3637. 29 April 2024

Directed and acyclic synaptic connectivity in the human layer 2-3 cortical microcircuit.
Peng, Y. and Bjelde, A. and Aceituno, P.V. and Mittermaier, F.X. and Planert, H. and Grosser, S. and Onken, J. and Faust, K. and Kalbhenn, T. and Simon, M. and Radbruch, H. and Fidzinski, P. and Schmitz, D. and Alle, H. and Holtkamp, M. and Vida, I. and Grewe, B.F. and Geiger, J.R.P.
Science 384 (6693): 338-343. 26 April 2024

BTK inhibition limits microglia‑perpetuated CNS inflammation and promotes myelin repair.
Geladaris, A. and Torke, S. and Saberi, D. and Alankus, Y.B. and Streit, F. and Zechel, S. and Stadelmann-Nessler, C. and Fischer, A. and Boschert, U. and Häusler, D. and Weber, M.S.
Acta Neuropathologica 147 (1): 75. 24 April 2024

Grainyhead-like 2 deficiency and kidney cyst growth in a mouse model.
Yurtdas, Z.Y. and Kilic, E. and Boor, P. and Wyler, E. and Landthaler, M. and Jung, K. and Schmidt-Ott, K.M.
Journal of the American Society of Nephrology 24 April 2024 (In Press)

A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on pulmonary circulation & right ventricular function.
Ameri, P. and Mercurio, V. and Pollesello, P. and Anker, M.S. and Backs, Jo. and Bayes-Genis, A. and Borlaug, B.A. and Burkhoff, D. and Caravita, S. and Chan, S.Y. and de Man, F. and Giannakoulas, G. and González, A. and Guazzi, M. and Hassoun, P.M. and Hemnes, A.R. and Maack, C. and Madden, B. and Melenovsky, V. and Müller, O.J. and Papp, Z. and Pullamsetti, S.S. and Rainer, P.P. and Redfield, M.M. and Rich, S. and Schiattarella, G.G. and Skaara, H. and Stellos, K. and Tedford, R.J. and Thum, T. and Vachiery, J.L. and van der Meer, P. and Van Linthout, S. and Pruszczyk, P. and Seferovic, P. and Coats, A.J.S. and Metra, M. and Rosano, G. and Rosenkranz, S. and Tocchetti, C.G.
European Journal of Heart Failure 19 April 2024 (In Press)

Dynamics of clonal hematopoiesis under DNA-damaging treatment in patients with ovarian cancer.
Arends, C.M. and Kopp, K. and Hablesreiter, R. and Estrada, N. and Christen, F. and Moll, U.M. and Zeillinger, R. and Schmitt, W.D. and Sehouli, J. and Kulbe, H. and Fleischmann, M. and Ray-Coquard, I. and Zeimet, A. and Raspagliesi, F. and Zamagni, C. and Vergote, I. and Lorusso, D. and Concin, N. and Bullinger, L. and Braicu, E.I. and Damm, F.
Leukemia 18 April 2024 (In Press)

Increased β(2)-adrenergic signaling promotes fracture healing through callus neovascularization in mice.
Jahn, D. and Knapstein, P.R. and Otto, E. and Köhli, P. and Sevecke, J. and Graef, F. and Graffmann, C. and Fuchs, M. and Jiang, S. and Rickert, M. and Erdmann, C. and Appelt, J. and Revend, L. and Küttner, Q. and Witte, J. and Rahmani, A. and Duda, G. and Xie, W. and Donat, A. and Schinke, T. and Ivanov, A. and Tchouto, M.N. and Beule, D. and Frosch, K.H. and Baranowsky, A. and Tsitsilonis, S. and Keller, J.
Science Translational Medicine 16 (743): eadk9129. 17 April 2024

Water conservation overrides osmotic diuresis during SGLT2 inhibition in patients with heart failure.
Marton, A. and Saffari, S.E. and Rauh, M. and Sun, R.N. and Nagel, A.M. and Linz, P. and Lim, T.T. and Takase-Minegishi, K. and Pajarillaga, A. and Saw, S. and Morisawa, N. and Yam, W.K. and Minegishi, S. and Totman, J.J. and Teo, S. and Teo, L.L.Y. and Ng, C.T. and Kitada, K. and Wild, J. and Kovalik, J.P. and Luft, F.C. and Greasley, P.J. and Chin, C.W.L. and Sim, D.K.L. and Titze, J.
Journal of the American College of Cardiology 83 (15): 1386-1398. 16 April 2024

Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation.
Tiniakou, I. and Hsu, P.F. and Lopez-Zepeda, L.S. and Garipler, G. and Esteva, E. and Adams, N.M. and Jang, G. and Soni, C. and Lau, C.M. and Liu, F. and Khodadadi-Jamayran, A. and Rodrick, T.C. and Jones, D. and Tsirigos, A. and Ohler, U. and Bedford, M.T. and Nimer, S.D. and Kaartinen, V. and Mazzoni, E.O. and Reizis, B.
Science Immunology 9 (94): eadi1023. 12 April 2024

Making AML fly too close to the sun.
Bullinger, L. and Krönke, J.
Blood 143 (15): 1438-1439. 11 April 2024

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T. and Meyer, K. and Roske, Y. and Uyar, B. and Akalin, A. and Imami, K. and Ishihama, Y. and Daumke, O. and Selbach, M.
Nature Communications 15 (1): 3146. 11 April 2024

Smoking-associated gene expression alterations in nasal epithelium reveal immune impairment linked to lung cancer risk.
de Biase, M.S. and Massip, F. and Wei, T.T. and Giorgi, F.M. and Stark, R. and Stone, A. and Gladwell, A. and O'Reilly, M. and Schütte, D. and de Santiago, I. and Meyer, K.B. and Markowetz, F. and Ponder, B.A.J. and Rintoul, R.C. and Schwarz, R.F.
Genome Medicine 16 (1): 54. 8 April 2024

ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection.
Bredow, C. and Thery, F. and Wirth, E.K. and Ochs, S. and Kespohl, M. and Kleinau, G. and Kelm, N. and Gimber, N. and Schmoranzer, J. and Voss, M. and Klingel, K. and Spranger, J. and Renko, K. and Ralser, M. and Mülleder, M. and Heuser, A. and Knobeloch, K.P. and Scheerer, P. and Kirwan, J. and Brüning, U. and Berndt, N. and Impens, F. and Beling, A.
Cardiovascular Research 120 (6): 644-657. 6 April 2024

Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry.
Ben Hamza, A. and Welters, C. and Stadler, S. and Brüggemann, M. and Dietze, K. and Brauns, O. and Brümmendorf, T.H. and Winkler, T.H. and Bullinger, L. and Blankenstein, T. and Rosenberger, L. and Leisegang, M. and Kammertöns, T. and Herr, W. and Moosmann, A. and Strobel, J. and Hackstein, H. and Dornmair, K. and Beier, F. and Hansmann, L.
Blood 143 (14): 1365-1378. 4 April 2024

Cell states in cancer: drivers, passengers, and trailers.
Gargiulo, G. and Serresi, M. and Marine, J.C.
Cancer Discovery 14 (4): 610-614. 4 April 2024

Basal delamination during mouse gastrulation primes pluripotent cells for differentiation.
Sato, N. and Rosa, V.S. and Makhlouf, A. and Kretzmer, H. and Sampath Kumar, A. and Grosswendt, S. and Mattei, A.L. and Courbot, O. and Wolf, S. and Boulanger, J. and Langevin, F. and Wiacek, M. and Karpinski, D. and Elosegui-Artola, A. and Meissner, A. and Zernicka-Goetz, M. and Shahbazi, M.N.
Developmental Cell 4 April 2024 (In Press)

Efficient recovery of complete gut viral genomes by combined short- and long-read sequencing.
Chen, J. and Sun, C. and Dong, Y. and Jin, M. and Lai, S. and Jia, L. and Zhao, X. and Wang, H. and Gao, N.L. and Bork, P. and Liu, Z. and Chen, W.H. and Zhao, X.M.
Advanced Science 11 (13): 2305818. 3 April 2024

External mechanical stability regulates hematoma vascularization in bone healing rather than endothelial YAP/TAZ mechanotransduction.
Mehl, J. and Farahani, S.K. and Brauer, E. and Klaus-Bergmann, A. and Thiele, T. and Ellinghaus, A. and Bartels-Klein, E. and Koch, K. and Schmidt-Bleek, K. and Petersen, A. and Gerhardt, H. and Vogel, V. and Duda, G.N.
Advanced Science 11 (13): e2307050. 3 April 2024

The Calmodulin-interacting peptide Pcp4a regulates feeding state-dependent behavioral choice in zebrafish.
Zaupa, M. and Nagaraj, N. and Sylenko, A. and Baier, H. and Sawamiphak, S. and Filosa, A.
Neuron 112 (7): 1150-1164.e6. 3 April 2024

Exploring mechanisms of lipid nanoparticle-mucus interactions in healthy and cystic fibrosis conditions.
Tafech, B. and Rokhforouz, M.R. and Leung, J. and Sung, M.M. and Lin, P.J. and Sin, D.D. and Lauster, D. and Block, S. and Quon, B.S. and Tam, Y. and Cullis, P. and Feng, J.J. and Hedtrich, S.
Advanced Healthcare Materials : 2304525. 2 April 2024 (In Press)

Cellular senescence: Neither irreversible nor reversible.
Reimann, M. and Lee, S. and Schmitt, C.A.
Journal of Experimental Medicine 221 (4): e20232136. 1 April 2024

Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients.
Fislage, M. and Winzeck, S. and Woodrow, R. and Lammers-Lietz, F. and Stamatakis, E.A. and Correia, M.M. and Preller, J. and Feinkohl, I. and Hendrikse, J. and Pischon, T. and Spies, C.D. and Slooter, A.J.C. and Winterer, G. and Menon, D.K. and Zacharias, N.
Alzheimer's and Dementia 20 (4): 2861-2872. April 2024

Pangenome graph construction from genome alignments with Minigraph-Cactus.
Hickey, G. and Monlong, J. and Ebler, J. and Novak, A.M. and Eizenga, J.M. and Gao, Y. and Marschall, T. and Li, H. and Paten, B.
Nature Biotechnology 42 (4): 663-673. April 2024

TF-FVIIa PAR2-β-arrestin in mouse signaling sustains organ dysfunction in coxsackievirus B3 infection.
Kespohl, M. and Goetzke, C.C. and Althof, N. and Bredow, C. and Kelm, N. and Pinkert, S. and Bukur, T. and Bukur, V. and Grunz, K. and Kaur, D. and Heuser, A. and Mülleder, M. and Sauter, M. and Klingel, K. and Weiler, H. and Berndt, N. and Gaida, M.M. and Ruf, W. and Beling, A.
Arteriosclerosis Thrombosis and Vascular Biology 44 (4): 843-865. April 2024

Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials.
Sun, M.L. and Yao, W. and Wang, X.Y. and Gao, S. and Varady, K.A. and Forslund, S.K. and Zhang, M. and Shi, Z.Y. and Cao, F. and Zou, B.J. and Sun, M.H. and Liu, K.X. and Bao, Q. and Xu, J. and Qin, X. and Xiao, Q. and Wu, L. and Zhao, Y.H. and Zhang, D.Y. and Wu, Q.J. and Gong, T.T
EClinicalMedicine 70 : 102519. April 2024

Post-hoc standardisation of parametric T1 maps in cardiovascular magnetic resonance imaging: a proof-of-concept.
Viezzer, D. and Hadler, T. and Gröschel, J. and Ammann, C. and Blaszczyk, E. and Kolbitsch, C. and Hufnagel, S. and Kranzusch-Groß, R. and Lange, S. and Schulz-Menger, J.
EBioMedicine 102 : 105055. April 2024

HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation.
Welters, C. and Welters, M.L. and Stadler, S. and Bullinger, L. and Strobel, J. and Hackstein, H. and Dhamodaran, A. and Blankenstein, T. and Hansmann, L.
Haematologica 109 (4): 1121-1127. April 2024

Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner, P.J. and Anandakumar, H. and Röwekamp, I. and Fiocca Vernengo, F. and Millet Pascual-Leone, B. and Krzanowski, M. and Sellmaier, J. and Brüning, U. and Fritsche-Guenther, R. and Pfannkuch, L. and Kurth, F. and Milek, M. and Igbokwe, V. and Löber, U. and Gutbier, B. and Holstein, M. and Heinz, G.A. and Mashreghi, M.F. and Schulte, L.N. and Klatt, A.B. and Caesar, S. and Wienhold, S.M. and Offermanns, S. and Mack, M. and Witzenrath, M. and Jordan, S. and Beule, D. and Kirwan, J.A. and Forslund, S.K. and Wilck, N. and Bartolomaeus, H. and Heimesaat, M.M. and Opitz, B.
Nature Communications 15 (1): 2788. 30 March 2024

Review: Opportunities and barriers for omics-based biomarker discovery in steatotic liver diseases.
Thiele, M. and Villesen, I.. and Niu, L. and Johansen, S. and Sulek, K. and Nishijima, S. and Van Espen, L. and Keller, M. and Israelsen, M. and Suvitaival, T. and de Zawadzki, A. and Juel, H.B. and Brol, M.J. and Stinson, S.E. and Huang, Y. and Alvarez Silva, M.C. and Kuhn, M. and Anastasiadou, E. and Leeming, D.J. and Karsdal, M. and Matthijnssens, J. and Arumugam, M. and Dalgaard, L.T. and Legido-Quigley, C. and Mann, M. and Trebicka, J. and Bork, P. and Jensen, L.J. and Hansen, T. and Krag, A.
Journal of Hepatology 28 March 2024 (In Press)

Microglial sex differences in innate high anxiety and modulatory effects of minocycline.
Ugursu, B. and Sah, A. and Sartori, S. and Popp, O. and Mertins, P. and Dunay, I.R. and Kettenmann, H. and Singewald, N. and Wolf, S.A.
Brain, Behavior and Immunity 27 March 2024 (In Press)

Ion mobility-tandem mass spectrometry of mucin-type O-glycans.
Bechtella, L. and Chunsheng, J. and Fentker, K. and Ertürk, G.R. and Safferthal, M. and Polewski, Ł. and Götze, M. and Graeber, S.Y. and Vos, G.M. and Struwe, W.B. and Mall, M.A. and Mertins, P. and Karlsson, N.G. and Pagel, K.
Nature Communications 15 (1): 2611. 23 March 2024

A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Brenner, D. and Sieverding, K. and Srinidhi, J. and Zellner, S. and Secker, C. and Yilmaz, R. and Dyckow, J. and Amr, S. and Ponomarenko, A. and Tunaboylu, E. and Douahem, Y. and Schlag, J.S. and Rodríguez Martínez, L. and Kislinger, G. and Niemann, C. and Nalbach, K. and Ruf, W.P. and Uhl, J. and Hollenbeck, J. and Schirmer, L. and Catanese, A. and Lobsiger, C.S. and Danzer, K.M. and Yilmazer-Hanke, D. and Münch, C. and Koch, P. and Freischmidt, A. and Fetting, M. and Behrends, C. and Parlato, R. and Weishaupt, J.H.
Journal of Experimental Medicine 221 (5): e20221190. 22 March 2024

Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment.
Kaiser, R. and Gold, C. and Joppich, M. and Loew, Q. and Akhalkatsi, A. and Mueller, T.T. and Offensperger, F. and Droste Zu Senden, A. and Popp, O. and di Fina, L. and Knottenberg, V. and Martinez-Navarro, A. and Eivers, L. and Anjum, A. and Escaig, R. and Bruns, N. and Briem, E. and Dewender, R. and Muraly, A. and Akgöl, S. and Ferraro, B. and Hoeflinger, J.K.L. and Polewka, V. and Khaled, N.B. and Allgeier, J. and Tiedt, S. and Dichgans, M. and Engelmann, B. and Enard, W. and Mertins, P. and Hubner, N. and Weckbach, L. and Zimmer, R. and Massberg, S. and Stark, K. and Nicolai, L. and Pekayvaz, K.
Science Advances 10 (12): eadl1710. 22 March 2024

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022.
Baumgartner, F. and Baer, C. and Bamopoulos, S.A. and Ayoub, E. and Truger, M. and Meggendorfer, M. and Lenk, M. and Hoermann, G. and Hutter, S. and Müller, H. and Walter, W. and Mueller, M.L. and Nadarajah, Ni. and Blombery, P. and Keller, U. and Kern, W. and Haferlach, C. and Haferlach, T.
Blood 143 (12): 1139-1156. 21 March 2024

Heterozygous missense variant in GLI2 impairs human endocrine pancreas development.
Mueller, L.M. and Isaacson, A. and Wilson, H. and Salowka, A. and Tay, I. and Gong, M. and Samir Elbarbary, N. and Raile, K. and Spagnoli, F.M.
Nature Communications 15 (1): 2483. 20 March 2024

Despite the odds: formation of the SARS-CoV-2 methylation complex.
Matsuda, A. and Plewka, J. and Rawski, M. and Mourão, A. and Zajko, W. and Siebenmorgen, T. and Kresik, L. and Lis, K. and Jones, A.N. and Pachota, M. and Karim, A. and Hartman, K. and Nirwal, S. and Sonani, R. and Chykunova, Y. and Minia, I. and Mak, P. and Landthaler, M. and Nowotny, M. and Dubin, G. and Sattler, M. and Suder, P. and Popowicz, G.M. and Pyrć, K. and Czarna, A.
Nucleic Acids Research : gkae165. 18 March 2024 (In Press)

Clonal dominance defines metastatic dissemination in pancreatic cancer.
Ho, I.L. and Li, C.Y. and Wang, F. and Zhao, L. and Liu, J. and Yen, E.Y. and Dyke, C.A. and Shah, R. and Liu, Z. and Çetin, A.O. and Chu, Y. and Citron, F. and Attanasio, S. and Corti, D. and Darbaniyan, F. and Del Poggetto, E. and Loponte, S. and Liu, J. and Soeung, M. and Chen, Z. and Jiang, S. and Jiang, H. and Inoue, A. and Gao, S. and Deem, A. and Feng, N. and Ying, H. and Kim, M. and Giuliani, V. and Genovese, G. and Zhang, J. and Futreal, A. and Maitra, A. and Heffernan, T. and Wang, L. and Do, K.A. and Gargiulo, G. and Draetta, G. and Carugo, A. and Lin, R. and Viale, A.
Science Advances 10 (11): eadd9342. 15 March 2024

Rigorous science demands support of transgender scientists.
Aghi, K. and Anderson, B.M. and Castellano, B.M. and Cunningham, A. and Delano, M. and Dickinson, E.S. and von Diezmann, L. and Forslund-Startceva, S.K. and Grijseels, D.M. and Groh, S.S. and Guthman, E.M. and Jayasinghe, I. and Johnston, J. and Long, S. and McLaughlin, J.F. and McLaughlin, M. and Miyagi, M. and Rajaraman, B. and Sancheznieto, F. and Scheim, A.I. and Sun, S.E.D. and Titmuss, F.D. and Walsh, R.J. and Weinberg, Z.Y.
Cell 187 (6): 1327-1334. 14 March 2024

CD19-targeting CAR T cells protect from ANCA-induced acute kidney injury.
Lodka, D. and Zschummel, M. and Bunse, M. and Rousselle, A. and Sonnemann, J. and Kettritz, R. and Höpken, U.E. and Schreiber, A.
Annals of the Rheumatic Diseases 83 (4): 499-507. 12 March 2024

Genetic determinants of micronucleus formation in vivo.
Adams, D.J. and Barlas, B. and McIntyre, R.E. and Salguero, I. and van der Weyden, L. and Barros, A. and Vicente, J.R. and Karimpour, N. and Haider, A. and Ranzani, M. and Turner, G. and Thompson, N.A. and Harle, V. and Olvera-León, R. and Robles-Espinoza, C.D. and Speak, A.O. and Geisler, N. and Weninger, W.J. and Geyer, S.H. and Hewinson, J. and Karp, N.A. and Fu, B. and Yang, F. and Kozik, Z. and Choudhary, J. and Yu, L. and van Ruiten, M.S. and Rowland, B.D. and Lelliott, C.J. and Del Castillo Velasco-Herrera, M. and Verstraten, R. and Bruckner, L. and Henssen, A.G. and Rooimans, M.A. and de Lange, J. and Mohun, T.J. and Arends, M.J. and Kentistou, K.A. and Coelho, P.A. and Zhao, Y. and Zecchini, H. and Perry, J.R.B. and Jackson, S.P. and Balmus, G.
Nature 627 (8002): 130–136. 7 March 2024

Canonical and non-canonical integrin-based adhesions dynamically interconvert.
Lukas, F. and Matthaeus, C. and López-Hernández, T. and Lahmann, I. and Schultz, N. and Lehmann, M. and Puchkov, D. and Pielage, J. and Haucke, V. and Maritzen, T.
Nature Communications 15 (1): 2093. 7 March 2024

Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer.
Bei, Y. and Brame, Luca and Kirchner, M. and Fritsche-Guenther, R. and Kunz, S. and Bhattacharya, A. and Rusu, M.C. and Gürgen, D. and Dubois, F.P.B. and Köppke, J.K.C. and Proba, J. and Wittstruck, N. and Sidorova, O.A. and Chamorro González, R. and Dorado Garcia, H. and Brückner, L. and Xu, R. and Giurgiu, M. and Rodriguez-Fos, E. and Yu, Q. and Spanjaard, B. and Koche, R.P, and Schmitt, C.A. and Schulte, J.H. and Eggert, A. and Haase, K. and Kirwan, J. and Hagemann, A.I. and Mertins, P. and Dörr, J.R. and Henssen, A.G.
Cancer Discovery 14 (3): 492-507. 1 March 2024

Touch sensation requires the mechanically gated ion channel ELKIN1.
Chakrabarti, S. and Klich, J.D. and Khallaf, M.A. and Hulme, A.J. and Sánchez-Carranza, O. and Baran, Z.M. and Rossi, A. and Huang, A.T.L. and Pohl, T. and Fleischer, R. and Fürst, C. and Hammes, A. and Bégay, V. and Hörnberg, H. and Finol-Urdaneta, R.K. and Poole, K. and Dottori, M. and Lewin, G.
Science 383 (6686): 992-998. 1 March 2024

Impact of individualized treatment on recovery from fatigue and return to work in survivors of advanced stage Hodgkin Lymphoma: results from the randomized international GHSG HD18 trial.
Ferdinandus, J. and Müller, H. and Damaschin, C. and Jacob, A.S. and Meissner, J. and Krasniqi, F. and Mey, U. and Schöndube, D. and Thiemer, J. and Mathas, S. and Zijlstra, J. and Greil, R. and Feuring-Buske, M. and Markova, J. and Rüffer, J.U. and Kobe, C. and Eich, H.T. and Baues, C. and Fuchs, M. and Borchmann, P. and Behringer, K.
Annals of Oncology 35 (3): 276-284. March 2024

Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories.
Gross, C.C. and Schulte-Mecklenbeck, A. and Steinberg, O.V. and Wirth, T. and Lauks, S. and Bittner, S. and Schindler, P. and Baranzini, S.E. and Groppa, S. and Bellmann-Strobl, J. and Bünger, N. and Chien, C. and Dawin, E. and Eveslage, M. and Fleischer, V. and Gonzalez-Escamilla, G. and Gisevius, B. and Haas, J. and Kerschensteiner, M. and Kirstein, L. and Korsukewitz, C. and Lohmann, L. and Lünemann, J.D. and Luessi, F. and Meyer Zu Hörste, G. and Motte, J. and Ruck, T. and Ruprecht, K. and Schwab, N. and Steffen, F. and Meuth, S.G. and Paul, F. and Wildemann, B. and Kümpfel, T. and Gold, R. and Hahn, T. and Zipp, F. and Klotz, L. and Wiendl, H.
Science Translational Medicine 16 (740): eade8560. March 2024

High-throughput anaerobic screening for identifying compounds acting against gut bacteria in monocultures or communities.
Müller, P. and de la Cuesta-Zuluaga, J. and Kuhn, M. and Baghai Arassi, M. and Treis, T. and Blasche, S. and Zimmermann, M. and Bork, P. and Patil, K.R. and Typas, A. and Garcia-Santamarina, S. and Maier, L.
Nature Protocols 19 (3): 668-699. March 2024

Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Radke, J. and Meinhardt, J. and Aschman, T. and Chua, R.L. and Farztdinov, V. and Lukassen, S. and Ten, F.W. and Friebel, E. and Ishaque, N. and Franz, J. and Huhle, V.H. and Mothes, R. and Peters, K. and Thomas, C. and Schneeberger, S. and Schumann, E. and Kawelke, L. and Jünger, J. and Horst, V. and Streit, S. and von Manitius, R. and Körtvélyessy, P. and Vielhaber, S. and Reinhold, D. and Hauser, A.E. and Osterloh, A. and Enghard, P. and Ihlow, J. and Elezkurtaj, S. and Horst, D. and Kurth, F. and Müller, M.A. and Gassen, N.C. and Melchert, J. and Jechow, K. and Timmermann, B. and Fernandez-Zapata, C. and Böttcher, C. and Stenzel, W. and Krüger, E. and Landthaler, M. and Wyler, E. and Corman, V. and Stadelmann, C. and Ralser, M. and Eils, R. and Heppner, F.L. and Mülleder, M. and Conrad, C. and Radbruch, H.
Nature Neuroscience 27 (3): 409-420. March 2024

High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA): a single-arm, phase 2 trial.
Schorb, E. and Isbell, L.K. and Kerkhoff, A. and Mathas, S. and Braulke, F. and Egerer, G. and Röth, A. and Schliffke, S. and Borchmann, P. and Brunnberg, U. and Kroschinsky, F. and Möhle, R. and Rank, A. and Wellnitz, D. and Kasenda, B. and Pospiech, L. and Wendler, J. and Scherer, F. and Deckert, M. and Henkes, E. and von Gottberg, P. and Gmehlin, D. and Backenstraß, M. and Jensch, A. and Burger-Martin, E. and Grishina, O. and Fricker, H. and Malenica, N. and Orbán, A. and Duyster, J. and Ihorst, G. and Finke, J. and Illerhaus, G.
Lancet Haematology 11 (3): e196-e205. March 2024

Comparable CD8(+) T-cell responses to SARS-CoV-2 vaccination in single-cell transcriptomics of recently allogeneic transplanted patients and healthy individuals.
Tranter, Eva and Frentsch, Marco and Hütter-Krönke, Marie Luise and Vuong, Giang Lam and Busch, David and Loyal, Lucie and Henze, Larissa and Rosnev, Stanislav and Blau, Igor-Wolfgang and Thiel, Andreas and Beule, D. and Bullinger, L. and Obermayer, B. and Na, I.K.
Journal of medical virology 96 (3): e29539. March 2024

Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Flügel, T. and Schacherl, M. and Unbehaun, A. and Schroeer, B. and Dabrowski, M. and Bürger, J. and Mielke, T. and Sprink, T. and Diebolder, C.A. and Guillén Schlippe, Y.V. and Spahn, C.M.T.
Nature Communications 15 (1): 1756. 26 February 2024

MarShie: a clearing protocol for 3D analysis of single cells throughout the bone marrow at subcellular resolution.
Mertens, T.F. and Liebheit, A.T. and Ehl, J. and Köhler, R. and Rakhymzhan, A. and Woehler, A. and Katthän, L. and Ebel, G. and Liublin, W. and Kasapi, A. and Triantafyllopoulou, A. and Schulz, T.J. and Niesner, R.A. and Hauser, A.E.
Nature Communications 15 (1): 1764. 26 February 2024

From gut to heart: role of indole-3-propionic acid in HFpEF.
Vacca, A. and Schiattarella, G.G.
Circulation Research 134 (4): 390-392. 16 February 2024

Structural insights into the activation mechanism of antimicrobial GBP1.
Weismehl, M. and Chu, X. and Kutsch, M. and Lauterjung, P. and Herrmann, C. and Kudryashev, M. and Daumke, O.
EMBO Journal 43 (4): 615-636. 15 February 2024

The cycling and aging mouse female reproductive tract at single-cell resolution.
Winkler, I. and Tolkachov, A. and Lammers, F. and Lacour, P. and Daugelaite, K. and Schneider, N. and Koch, M.L. and Panten, J. and Grünschläger, F. and Poth, T. and Ávila, B.M.d. and Schneider, A. and Haas, S. and Odom, D.T. and Gonçalves, Â.
Cell 187 (4): 981-998. 15 February 2024

Metrics reloaded: recommendations for image analysis validation.
Maier-Hein, L. and Reinke, A. and Godau, P. and Tizabi, M.D. and Buettner, F. and Christodoulou, E. and Glocker, B. and Isensee, F. and Kleesiek, J. and Kozubek, M. and Reyes, M. and Riegler, M.A. and Wiesenfarth, M. and Kavur, A.E. and Sudre, C.H. and Baumgartner, M. and Eisenmann, M. and Heckmann-Nötzel, D. and Rädsch, T. and Acion, L. and Antonelli, M. and Arbel, T. and Bakas, S. and Benis, A. and Blaschko, M.B. and Cardoso, M.J. and Cheplygina, V. and Cimini, B.A. and Collins, G.S. and Farahani, K. and Ferrer, L. and Galdran, A. and van Ginneken, B. and Haase, R. and Hashimoto, D.A. and Hoffman, M.M. and Huisman, M. and Jannin, P. and Kahn, C.E. and Kainmueller, D. and Kainz, B. and Karargyris, A. and Karthikesalingam, A. and Kofler, F. and Kopp-Schneider, A. and Kreshuk, A. and Kurc, T. and Landman, B.A. and Litjens, G. and Madani, A. and Maier-Hein, K. and Martel, A.L. and Mattson, P. and Meijering, E. and Menze, B. and Moons, K.G.M. and Müller, H. and Nichyporuk, B. and Nickel, F. and Petersen, J. and Rajpoot, N. and Rieke, N. and Saez-Rodriguez, J. and Sánchez, C.I. and Shetty, S. and van Smeden, M. and Summers, R.M. and Taha, A.A. and Tiulpin, A. and Tsaftaris, S.A. and Van Calster, B. and Varoquaux, G. and Jäger, P.F.
Nature Methods 21 (2): 195-212. 12 February 2024

Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment.
Juul-Madsen, K. and Parbo, P. and Ismail, R. and Ovesen, P.L. and Schmidt, V. and Madsen, L.S. and Thyrsted, J. and Gierl, S. and Breum, M. and Larsen, A. and Andersen, M.N. and Romero-Ramos, M. and Holm, C.K. and Andersen, G.R. and Zhao, H. and Schuck, P. and Nygaard, J.V. and Sutherland, D.S. and Eskildsen, S.F. and Willnow, T.E. and Brooks, D.J. and Vorup-Jensen, T.
Nature Communications 15 (1): 1224. 9 February 2024

Functional and evolutionary significance of unknown genes from uncultivated taxa.
Rodríguez Del Río, Á. and Giner-Lamia, J. and Cantalapiedra, C.P. and Botas, J. and Deng, Z. and Hernández-Plaza, A. and Munar-Palmer, M. and Santamaría-Hernando, S. and Rodríguez-Herva, J.J. and Ruscheweyh, H.J. and Paoli, L. and Schmidt, T.S.B. and Sunagawa, S. and Bork, P. and López-Solanilla, E. and Coelho, L.P. and Huerta-Cepas, J.
Nature 626 (7998): 377-384. 8 February 2024

Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception.
Ojeda-Alonso, J. and Calvo-Enrique, L. and Paricio-Montesinos, R. and Kumar, R. and Zhang, M.D. and Poulet, J.F.A. and Ernfors, P. and Lewin, G.R.
Nature Communications 15 (1): 898. 6 February 2024

Structure and function of the hippocampal CA3 module.
Sammons, R.P. and Vezir, M. and Moreno-Velasquez, L. and Cano, G. and Orlando, M. and Sievers, M. and Grasso, E. and Metodieva, V.D. and Kempter, R. and Schmidt, H. and Schmitz, D.
Proceedings of the National Academy of Sciences of the United States of America 121 (6): e2312281120. 6 February 2024

Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes.
Company, C. and Schmitt, M.J. and Dramaretska, Y. and Serresi, M. and Kertalli, S. and Jiang, B. and Yin, J.A. and Aguzzi, A. and Barozzi, I. and Gargiulo, G.
Nature Communications 15 (1): 897. 5 February 2024

Gamma oscillation plasticity is mediated via parvalbumin interneurons.
Hadler, M.D. and Tzilivaki, A. and Schmitz, D. and Alle, H. and Geiger, J.R.P.
Science Advances 10 (5): eadj7427. 2 February 2024

Precise CRISPR-Cas9 gene repair in autologous memory T cells to treat familial hemophagocytic lymphohistiocytosis.
Li, X. and Wirtz, T. and Weber, T. and Lebedin, M. and Lowenstein, E.D. and Sommermann, T. and Zach, A. and Yasuda, T. and de la Rosa, K. and Chu, V.T. and Schulte, J.H. and Müller, I. and Kocks, C. and Rajewsky, K.
Science Immunology 9 (92): eadi0042. 2 February 2024

A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea.
Mottaghinia, S. and Stenzel, S. and Tsangaras, K. and Nikolaidis, N. and Laue, M. and Müller, K. and Hölscher, H. and Löber, U. and McEwen, G.K. and Donnellan, S.C. and Rowe, K.C. and Aplin, K.P. and Goffinet, C. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 121 (6): e2220392121. 1 February 2024

Genetic characterization of primary mediastinal B-cell lymphoma: pathogenesis and patient outcomes.
Noerenberg, D. and Briest, F. and Hennch, C. and Yoshida, K. and Hablesreiter, R. and Takeuchi, Y. and Ueno, H. and Staiger, A.M. and Ziepert, M. and Asmar, F. and Locher, B.N. and Toth, E. and Weber, T. and Amini, R.M. and Klapper, W. and Bouzani, M. and Poeschel, V. and Rosenwald, A. and Held, G. and Campo, E. and Ishaque, N. and Stamatopoulos, K. and Kanellis, G. and Anagnostopoulos, I. and Bullinger, L. and Goldschmidt, N. and Zinzani, P.L. and Bödör, C. and Rosenquist, R. and Vassilakopoulos, T.P. and Ott, G. and Ogawa, S. and Damm, F.
Journal of Clinical Oncology 42 (4): 452-466. 1 February 2024

Update and European consensus on a patient-centered core outcome set for multiple myeloma in clinical practice and research.
Oerlemans, S. and De Rooij, B.H. and Bennink, C. and Bullinger, L. and Broijl, A. and D'Agostino, M. and Laane, E. and Lupo-Stanghellini, M.T. and Perrot, A. and Wester, R. and Cursaru, V. and Scheurer, H. and Vesseur, J. and Dalal, M. and Sen, R. and Stamm, T. and Ludwig, H. and Sonneveld, P.
Haematologica 1 February 2024 (In Press)

Epigenetic regulatory layers in the 3D nucleus.
Willemin, A. and Szabo, D. and Pombo, A.
Molecular Cell 84 (3): 415-428. 1 February 2024

A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses.
Brunner, T.M. and Serve, S. and Marx, A.F. and Fadejeva, J. and Saikali, P. and Dzamukova, M. and Durán-Hernández, N. and Kommer, C. and Heinrich, F. and Durek, P. and Heinz, G.A. and Höfer, T. and Mashreghi, M.F. and Kühn, R. and Pinschewer, D.D. and Löhning, M.
Nature Immunology 25 (2): 256-267. February 2024

SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction.
Gotthardt, M. and Lehnart, S.E.
Cardiovascular Research 120 (3): 220-222. February 2024

CoNIC Challenge: Pushing the frontiers of nuclear detection, segmentation, classification and counting.
Graham, S. and Vu, Q.D. and Jahanifar, M. and Weigert, M. and Schmidt, U. and Zhang, W. and Zhang, J. and Yang, S. and Xiang, J. and Wang, X. and Rumberger, J.L. and Baumann, E. and Hirsch, P. and Liu, L. and Hong, C. and Aviles-Rivero, A.I. and Jain, A. and Ahn, H. and Hong, Y. and Azzuni, H. and Xu, M. and Yaqub, M. and Blache, M.C. and Piégu, B. and Vernay, B. and Scherr, T. and Böhland, M. and Löffler, K. and Li, J. and Ying, W. and Wang, C. and Snead, D. and Raza, S.E.A. and Minhas, F. and Rajpoot, N.M.
Medical Image Analysis 92 : 103047. February 2024

Frequent, high density expression of surface CD38 as a potential therapeutic target in adult T-lineage acute lymphoblastic leukemia.
Koslowski, S. and Glauben, R. and Habringer, S. and Burmeister, T. and Keller, U. and Brüggemann, M. and Gökbuget, N. and Schwartz, S.
Haematologica 109 (2): 661-665. February 2024

The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Pan, X. and AbdulJabbar, K. and Coelho-Lima, J. and Grapa, A.I. and Zhang, H. and Cheung, A.H.K. and Baena, J. and Karasaki, T. and Wilson, C.R. and Sereno, M. and Veeriah, S. and Aitken, S.J. and Hackshaw, A. and Nicholson, A.G. and Jamal-Hanjani, M. and Swanton, C. and Yuan, Y. and Le Quesne, J. and Moore, D.A.
Nature Cancer 5 (2): 347-363. February 2024

GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway.
Park, A.Y. and Leney-Greene, M. and Lynberg, M. and Gabrielski, J.Q. and Xu, X. and Schwarz, B. and Zheng, L. and Balasubramaniyam, A. and Ham, H. and Chao, B. and Zhang, Y. and Matthews, H.F. and Cui, J. and Yao, Y. and Kubo, S. and Chanchu, J.M. and Morawski, A.R. and Cook, S.A. and Jiang, P. and Ravell, J.C. and Cheng, Y.H. and George, A. and Faruqi, A. and Pagalilauan, A.M. and Bergerson, J.R.E. and Ganesan, S. and Chauvin, S.D. and Aluri, J. and Edwards-Hicks, J. and Bohrnsen, E. and Tippett, C. and Omar, H. and Xu, L. and Butcher, G.W. and Pascall, J. and Karakoc-Aydiner, E. and Kiykim, A. and Maecker, H. and Tezcan, İ. and Esenboga, S. and Heredia, R.J. and Akata, D. and Tekin, S. and Kara, A. and Kuloglu, Z. and Unal, E. and Kendirli, T. and Dogu, F. and Karabiber, E. and Atkinson, T.P. and Cochet, C. and Filhol, O. and Bosio, C.M. and Davis, M.M. and Lifton, R.P. and Pearce, E.L. and Daumke, O. and Aytekin, C. and Şahin, G.E. and Aksu, A.Ü. and Uzel, G. and Koneti Rao, V. and Sari, S. and Boztug, K. and Cagdas, D. and Haskologlu, S. and Ikinciogullari, A. and Schwefel, D. and Vilarinho, S. and Baris, S. and Ozen, A. and Su, H.C. and Lenardo, M.J.
Nature Immunology 25 (2): 282-293. February 2024

Understanding metric-related pitfalls in image analysis validation.
Reinke, A. and Tizabi, M.D. and Baumgartner, M. and Eisenmann, M. and Heckmann-Nötzel, D. and Kavur, A.E. and Rädsch, T. and Sudre, C.H. and Acion, L. and Antonelli, M. and Arbel, T. and Bakas, S. and Benis, A. and Buettner, F. and Cardoso, M.J. and Cheplygina, V. and Chen, J. and Christodoulou, E. and Cimini, B.A. and Farahani, K. and Ferrer, L. and Galdran, A. and van Ginneken, B. and Glocker, B. and Godau, P. and Hashimoto, D.A. and Hoffman, M.M. and Huisman, M. and Isensee, F. and Jannin, P. and Kahn, C.E. and Kainmueller, D. and Kainz, B. and Karargyris, A. and Kleesiek, J. and Kofler, F. and Kooi, T. and Kopp-Schneider, A. and Kozubek, M. and Kreshuk, A. and Kurc, T. and Landman, B.A. and Litjens, G. and Madani, A. and Maier-Hein, K. and Martel, A.L. and Meijering, E. and Menze, B. and Moons, K.G.M. and Müller, H. and Nichyporuk, B. and Nickel, F. and Petersen, J. and Rafelski, S.M. and Rajpoot, N. and Reyes, M. and Riegler, M.A. and Rieke, N. and Saez-Rodriguez, J. and Sánchez, C.I. and Shetty, S. and Summers, R.M. and Taha, A.A. and Tiulpin, A. and Tsaftaris, S.A. and Van Calster, B. and Varoquaux, G. and Yaniv, Z.R. and Jäger, P.F. and Maier-Hein, L.
Nature Methods 21 (2): 182–194. February 2024

Selection on synonymous sites: the unwanted transcript hypothesis.
Radrizzani, S. and Kudla, G. and Izsvák, Z. and Hurst, L.D.
Nature Reviews Genetics 31 January 2024 (In Press)

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Hofman, D.A. and Ruiz-Orera, J. and Yannuzzi, I. and Murugesan, R. and Brown, A. and Clauser, K.R. and Condurat, A.L. and van Dinter, J.T. and Engels, S.A.G. and Goodale, A. and van der Lugt, J. and Abid, T. and Wang, L. and Zhou, K.N. and Vogelzang, J. and Ligon, K.L. and Phoenix, T.N. and Roth, J.A. and Root, D.E and Hubner, N. and Golub, T.R. and Bandopadhayay, P. and van Heesch, S. and Prensner, J.R.
Molecular Cell 84 (2): 261-276. 18 January 2024

Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz.
Uehata, T. and Yamada, S. and Ori, D. and Vandenbon, A. and Giladi, A. and Jelinski, A. and Murakawa, Y. and Watanabe, H. and Takeuchi, K. and Toratani, K. and Mino, T. and Kiryu, H. and Standley, D.M. and Tsujimura, T. and Ikawa, T. and Kondoh, G. and Landthaler, M. and Kawamoto, H. and Rodewald, H.R. and Amit, I. and Yamamoto, R. and Miyazaki, M. and Takeuchi, O.
Blood 143 (3): 243-257. 18 January 2024

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.
Drexhage, L.Z. and Zhang, S. and Dupont, M. and Ragaller, F. and Sjule, E. and Cabezas-Caballero, J. and Deimel, L.P. and Robertson, H. and Russell, R.A. and Dushek, O. and Sezgin, E. and Karaji, N. and Sattentau, Q.J.
Nature Communications 15 (1): 541. 15 January 2024

Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Roske, Y. and Cappel, C. and Cremer, N. and Hoffmann, P. and Koudelka, T. and Tholey, A. and Heinemann, U. and Daumke, O. and Damme, M.
Nucleic Acids Research 52 (1): 370-384. 11 January 2024

Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex.
Giehler, F. and Ostertag, M.S. and Sommermann, T. and Weidl, D. and Sterz, K.R. and Kutz, H. and Moosmann, A. and Feller, S.M. and Geerlof, A. and Biesinger, B. and Popowicz, G.M. and Kirchmair, J. and Kieser, A.
Nature Communications 15 (1): 414. 10 January 2024

High-sensitivity cardiac troponin I enhances preeclampsia prediction beyond maternal factors and the sFlt-1/PlGF ratio.
Bacmeister, L. and Goßling, A. and Buellesbach, A. and Birukov, A. and Myers, J.E. and Thomas, S.T. and Lee, S. and Andersen, M.S. and Jorgensen, J.S. and Diemert, A. and Blois, S.M. and Arck, P.C. and Hecher, K. and Herse, F. and Blankenberg, S. and Dechend, R. and Westermann, D. and Zeller, T.
Circulation 149 (2): 95-106. 9 January 2024

SPIRE: a Searchable, Planetary-scale mIcrobiome REsource.
Schmidt, T.S.B. and Fullam, A. and Ferretti, P. and Orakov, A. and Maistrenko, O.M. and Ruscheweyh, H.J. and Letunic, I. and Duan, Y. and Van Rossum, T. and Sunagawa, S. and Mende, D.R. and Finn, R.D. and Kuhn, M. and Pedro Coelho, L. and Bork, P.
Nucleic Acids Research 52 (D1): D777-D783. 5 January 2024

Cortical matrix remodeling as a hallmark of relapsing-remitting neuroinflammation in MR elastography and quantitative MRI.
Silva, R.V. and Morr, A.S. and Herthum, H. and Koch, S.P. and Mueller, S. and Batzdorf, C.S. and Bertalan, G. and Meyer, T. and Tzschätzsch, H. and Kühl, A.A. and Boehm-Sturm, P. and Braun, J. and Scheel, M. and Paul, F. and Infante-Duarte, C. and Sack, I.
Acta Neuropathologica 147 (1): 8. 4 January 2024

Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.
Borsa, M. and Obba, S. and Richter, F.C. and Zhang, H. and Riffelmacher, T. and Carrelha, J. and Alsaleh, G. and Jacobsen, S.E.W. and Simon, A.K.
Autophagy 20 (1): 45-57. January 2024

Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia.
Bruedigam, C. and Porter, A.H. and Song, A. and Vroeg In de Wei, G. and Stoll, T. and Straube, J. and Cooper, L. and Cheng, G. and Kahl, V.F.S. and Sobinoff, A.P. and Ling, V.Y. and Jebaraj, B.M.C. and Janardhanan, Y. and Haldar, R. and Bray, L.J. and Bullinger, L. and Heidel, F.H. and Kennedy, G.A. and Hill, M.M. and Pickett, H.A. and Abdel-Wahab, O. and Hartel, G. and Lane, S.W.
Nature Cancer 5 (1): 47-65. January 2024

Cancer evolution: a multifaceted affair.
Ciriello, G. and Magnani, L. and Aitken, S.J. and Akkari, L. and Behjati, S. and Hanahan, D. and Landau, D.A. and Lopez-Bigas, N. and Lupiáñez, D.G. and Marine, J.C. and Martin-Villalba, A. and Natoli, G. and Obenauf, A.C. and Oricchio, E. and Scaffidi, P. and Sottoriva, A. and Swarbrick, A. and Tonon, G. and Vanharanta, S. and Zuber, J.
Cancer Discovery 14 : 1-13. January 2024

Shared and distinct gut microbiota in spondyloarthritis, acute anterior uveitis, and Crohn's disease.
Essex, M. and Rios Rodriguez, V. and Rademacher, J. and Proft, F. and Löber, U. and Marko, L. and Pleyer, U. and Strowig, T. and Marchand, J. and Kirwan, J.A. and Siegmund, B. and Forslund, S.K. and Poddubnyy, D.
Arthritis & Rheumatology 76 (1): 48-58. January 2024

Making sense of proprioception.
Santuz, A. and Zampieri, N.
Trends in Genetics 40 (1): 20-23. January 2024

2023

Towards hierarchical regional transformer-based multiple instance learning.
Cersovsky, J. and Mohammadi, S. and Kainmueller, D. and Hoehne, J.
In: 2023 IEEE/CVF International Conference on Computer Vision Workshops (ICCVW), 02-06 Oct 2023, Paris, France. 25 December 2023

Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A. and Lahmann, I. and Nguyen, L.V.N. and Rost, B.R. and García-Pérez, A. and Lelievre, N. and Merritt-Garza, M.E. and Phan, H.C and Bassell, G.J. and Rossoll, W. and Diecke, S. and Kunz, S. and Schmitz, D. and Gouti, M.
Nature Communications 14 (1): 8043. 19 December 2023

Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.
Wang, Z. and Shaabani, S. and Gao, X. and Ng, Y.L.D. and Sapozhnikova, V. and Mertins, P. and Krönke, J. and Dömling, A.
Nature Communications 14 (1): 8437. 19 December 2023

Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice.
Funk, M.C. and Gleixner, J.G. and Heigwer, F. and Vonficht, D. and Valentini, E. and Aydin, Z. and Tonin, E. and Del Prete, S. and Mahara, S. and Throm, Y. and Hetzer, J. and Heide, D. and Stegle, O. and Odom, D.T. and Feldmann, A. and Haas, S. and Heikenwalder, M. and Boutros, M.
Developmental Cell 58 (24): 2914-2929. 18 December 2023

Impaired T cell IRE1α-XBP1 signaling directs inflammation in experimental Heart Failure with Preserved Ejection Fraction.
Smolgovsky, S. and Bayer, A.L. and Kaur, K. and Sanders, E. and Aronovitz, M. and Filipp, M.E. and Thorp, E.B. and Schiattarella, G.G. and Hill, J.A. and Blanton, R.M. and Cubillos-Ruiz, J.R. and Alcaide, P.
Journal of Clinical Investigation 133 (24): e171874. 15 December 2023

Autoantibodies against the chemokine receptor 3 predict cardiovascular risk.
Müller, F.S. and Aherrahrou, Z. and Grasshoff, H. and Heidorn, M.W. and Humrich, J.Y. and Johanson, L. and Aherrahrou, R. and Reinberger, T. and Schulz, A. and Ten Cate, V. and Robles, A.P. and Koeck, T. and Rapp, S. and Lange, T. and Brachaczek, L. and Luebber, F. and Erdmann, J. and Heidecke, H. and Schulze-Forster, K. and Dechend, R. and Lackner, K.J. and Pfeiffer, N. and Ghaemi Kerahrodi, J. and Tüscher, O. and Schwarting, A. and Strauch, K. and Münzel, T. and Prochaska, J.H. and Riemekasten, G. and Wild, P.S.
European Heart Journal 44 (47): 4935-4949. 14 December 2023

RIF1 regulates early replication timing in murine B cells.
Malzl, D. and Peycheva, M. and Rahjouei, A. and Gnan, S. and Klein, K.N. and Nazarova, M. and Schoeberl, U.E. and Gilbert, D.M. and Buonomo, S.C.B. and Di Virgilio, M. and Neumann, T. and Pavri, R.
Nature Communications 14 (1): 8049. 11 December 2023

Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Dönig, J. and Mende, H. and Davila Gallesio, J. and Wagner, K. and Hotz, P. and Schunck, K. and Piller, T. and Hölper, S. and Uhan, S. and Kaulich, M. and Wirth, M. and Keller, U. and Tascher, G. and Bohnsack, K.E. and Müller, S.
Nature Communications 14 (1): 8121. 8 December 2023

Turning science into cover art.
Dauben, H. and Matic, I. and Kidmose, R.T. and Pedersen, B.P. and Saha, T. and Di Virgilio, M. and Sung, J.H.
Trends in Biochemical Sciences 48 (12): 1009-1011. December 2023

Synthetic genetic circuits to uncover the OCT4 trajectories of successful reprogramming of human fibroblasts.
Ilia, K. and Shakiba, N. and Bingham, T. and Jones, R.D. and Kaminski, M.M. and Aravera, E. and Bruno, S. and Palacios, S. and Weiss, R. and Collins, J.J. and Del Vecchio, D. and Schlaeger, T.M.
Science Advances 9 (48): eadg8495. December 2023

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch, J. and Theisen, S. and Dartsch, J. and Fritsche-Guenther, R. and Kirchner, M. and Obermayer, B. and Bauer, A. and Kahlert, A.K. and Rothe, M. and Beule, D. and Heuser, A. and Mertins, P. and Kirwan, J.A. and Berndt, N. and MacRae, C.A. and Hubner, N. and Klaassen, S.
Cardiovascular Research 119 (18): 2902-2916. December 2023

Insm1 regulates mTEC development and immune tolerance.
Tao, W. and Ye, Z. and Wei, Y. and Wang, J. and Yang, W. and Yu, G. and Xiong, J. and Jia, S.
Cellular and Molecular Immunology 20 (12): 1472-1486. December 2023

The making of a proprioceptor: a tale of two identities.
de Nooij, J.C. and Zampieri, N.
Trends in Neurosciences 46 (12): 1083-1094. December 2023

The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation.
Benedum, J. and Franke, V. and Appel, L.M. and Walch, L. and Bruno, M. and Schneeweiss, R. and Gruber, J. and Oberndorfer, H. and Frank, E. and Strobl, X. and Polyansky, A. and Zagrovic, B. and Akalin, A. and Slade, D.
Nature Communications 14 (1): 7912. 30 November 2023

Associations of myeloid cells with cellular and humoral responses following vaccinations in patients with neuroimmunological diseases.
Wang, M. and Dehlinger, A. and Fernández Zapata, C. and Golan, M. and Gallaccio, G. and Sander, L.E. and Schlickeiser, S. and Kunkel, D. and Schmitz-Hübsch, T. and Sawitzki, B. and Karni, A. and Braun, J. and Loyal, L. and Thiel, A. and Bellmann-Strobl, J. and Paul, F. and Meyer-Arndt, L. and Boettcher, C.
Nature Communications 14 (1): 7728. 25 November 2023

Alpha-1 adrenergic signaling drives cardiac regeneration via extracellular matrix remodeling transcriptional program in zebrafish macrophages.
Apaydin, O. and Altaikyzy, A. and Filosa, A. and Sawamiphak, S.
Developmental Cell 58 (22): 2460-2476.e7. 20 November 2023

Latent human herpesvirus 6 is reactivated in CAR T cells.
Lareau, C.A. and Yin, Y. and Maurer, K. and Sandor, K.D. and Daniel, B. and Yagnik, G. and Peña, J. and Crawford, J.C. and Spanjaart, A.M. and Gutierrez, J.C. and Haradhvala, N.J. and Riberdy, J.M. and Abay, T. and Stickels, R.R. and Verboon, J.M. and Liu, V. and Buquicchio, F.A. and Wang, F. and Southard, J. and Song, R. and Li, W. and Shrestha, A. and Parida, L. and Getz, G. and Maus, M.V. and Li, S. and Moore, A. and Roberts, Z.J. and Ludwig, L.S. and Talleur, A.C. and Thomas, P.G. and Dehghani, H. and Pertel, T. and Kundaje, A. and Gottschalk, S. and Roth, T.L. and Kersten, M.J. and Wu, C.J. and Majzner, R.G. and Satpathy, A.T.
Nature 623 : 608-615. 16 November 2023

IL-33 expression is lower in current smokers at both transcriptomic and protein level.
Faiz, A. and Mahbub, R.M. and Boedijono, F.S. and Tomassen, M.I. and Kooistra, W. and Timens, W. and Nawijn, M. and Hansbro, P.M. and Johansen, M.D. and Pouwels, S.D. and Heijink, I.H. and Massip, F. and de Biase, M.S. and Schwarz, R.F. and Adcock, I.M. and Chung, K.F. and van der Does, A. and Hiemstra, P.S. and Goulaouic, H. and Xing, H. and Abdulai, R. and de Rinaldis, E. and Cunoosamy, D. and Harel, S. and Lederer, D. and Nivens, M.C. and Wark, P.A. and Kerstjens, H.A.M. and Hylkema, M.N. and Brandsma, C.A. and van den Berge, M.
American Journal of Respiratory and Critical Care Medicine 208 (10): 1075-1087. 15 November 2023

Lipid nanoparticle-mediated hit-and-run approaches yield efficient and safe in situ gene editing in human skin.
Bolsoni, J. and Liu, D. and Mohabatpour, F. and Ebner, R. and Sadhnani, G. and Tafech, B. and Leung, J. and Shanta, S. and An, K. and Morin, T. and Chen, Y. and Arguello, A. and Choate, K. and Jan, E. and Ross, C.J.D. and Brambilla, D. and Witzigmann, D. and Kulkarni, J. and Cullis, P.R. and Hedtrich, S.
ACS Nano 17 (21): 22046-22059. 14 November 2023

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes.
Chatzinikolaou, G. and Stratigi, K. and Siametis, A. and Goulielmaki, E. and Akalestou-Clocher, A. and Tsamardinos, I. and Topalis, P. and Austin, C. and Bouwman, B.A.M. and Crosetto, N. and Altmüller, J. and Garinis, G.A.
Science Advances 9 (45): eadi2095. 10 November 2023

Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells.
Reincke, S.M. and von Wardenburg, N. and Homeyer, M.A. and Kornau, H.C. and Spagni, G. and Li, L.Y. and Kreye, J. and Sánchez-Sendín, E. and Blumenau, S. and Stappert, D. and Radbruch, H. and Hauser, A.E. and Künkele, A. and Edes, I. and Schmitz, D. and Prüss, H.
Cell 186 (23): 5084-5097.e18. 9 November 2023

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma.
Finotto, L. and Cole, B. and Giese, W. and Baumann, E. and Claeys, A. and Vanmechelen, M. and Decraene, B. and Derweduwe, M. and Dubroja Lakic, N. and Shankar, G. and Nagathihalli Kantharaju, M. and Albrecht, J.P. and Geudens, I. and Stanchi, F. and Ligon, K.L. and Boeckx, B. and Lambrechts, D. and Harrington, K. and Van Den Bosch, L. and De Vleeschouwer, S. and De Smet, F. and Gerhardt, H.
EMBO Molecular Medicine 15 (11): e18144. 8 November 2023

Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N. and Cauchy, P. and Franke, V. and Giefing, M. and Fornes, O. and Vankadari, N. and Assi, S.A. and Costanza, M. and Weniger, M.A. and Akalin, A. and Anagnostopoulos, I. and Bukur, T. and Casarotto, M.G. and Damm, F. and Daumke, O. and Edginton-White, B. and Gebhardt, J.C.M. and Grau, M. and Grunwald, S. and Hansmann, M.L. and Hartmann, S. and Huber, L. and Kärgel, E. and Lusatis, S. and Noerenberg, D. and Obier, N. and Pannicke, U. and Fischer, A. and Reisser, A. and Rosenwald, A. and Schwarz, K. and Sundararaj, S. and Weilemann, A. and Winkler, W. and Xu, W. and Lenz, G. and Rajewsky, K. and Wasserman, W.W. and Cockerill, P.N. and Scheidereit, C. and Siebert, R. and Küppers, R. and Grosschedl, R. and Janz, M. and Bonifer, C. and Mathas, S.
Nature Communications 14 (1): 6947. 7 November 2023

Human embryo models: unveiling sophisticated self-organization of stem cells during post-implantation stages.
Lin, M. and Sigal, M.
Signal Transduction and Targeted Therapy 8 (1): 419. 6 November 2023

Leveraging large language models for decision support in personalized oncology.
Benary, M. and Wang, X.D. and Schmidt, M. and Soll, D. and Hilfenhaus, G. and Nassir, M. and Sigler, C. and Knödler, M. and Keller, U. and Beule, D. and Keilholz, U. and Leser, U. and Rieke, D.T.
JAMA Network Open 6 (11): e2343689. November 2023

Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F. and Noerenberg, D. and Hennch, C. and Yoshida, K. and Hablesreiter, R. and Nimo, J. and Sasca, D. and Kirchner, M. and Mansouri, L. and Inoue, Y. and Wiegand, L. and Staiger, A.M. and Casadei, B. and Korkolopoulou, P. and Weiner, J. and Lopez-Guillermo, A. and Warth, A. and Schneider, T. and Nagy, Á. and Klapper, W. and Hummel, M. and Kanellis, G. and Anagnostopoulos, I. and Mertins, P. and Bullinger, L. and Rosenquist, R. and Vassilakopoulos, T.P. and Ott, G. and Ogawa, S. and Damm, F.
Leukemia 37 (11): 2237-2249. November 2023

Mechanisms of substrate processing during ER-associated protein degradation.
Christianson, J.C. and Jarosch, E. and Sommer, T.
Nature Reviews Molecular Cell Biology 24 (11): 777-796. November 2023

Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.
Jahn, E. and Saadati, M. and Fenaux, P. and Gobbi, M. and Roboz, G.J. and Bullinger, L. and Lutsik, P. and Riedel, A. and Plass, C. and Jahn, N. and Walter, C. and Holzmann, K. and Hao, Y. and Naim, S. and Schreck, N. and Krzykalla, J. and Benner, A. and Keer, H.N. and Azab, M. and Döhner, K. and Döhner, H.
Leukemia 37 (11): 2187-2196. November 2023

Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver.
Nikopoulou, C. and Kleinenkuhnen, N. and Parekh, S. and Sandoval, T. and Ziegenhain, C. and Schneider, F. and Giavalisco, P. and Donahue, K.F. and Vesting, A.J. and Kirchner, M. and Bozukova, M. and Vossen, C. and Altmüller, J. and Wunderlich, T. and Sandberg, R. and Kondylis, V. and Tresch, A. and Tessarz, P.
Nature Aging 3 (11): 1430-1445. November 2023

Cox proportional hazards deep neural network identifies peripheral blood complete remission to be at least equivalent to morphologic complete remission in predicting outcomes of patients treated with azacitidine - a prospective cohort study by the AGMT.
Pleyer, L. and Vaisband, M. and Drost, M. and Pfeilstöcker, M. and Stauder, R. and Heibl, S. and Sill, H. and Girschikofsky, M. and Stampfl-Mattersberger, M. and Pichler, A. and Hartmann, B. and Petzer, A. and Schreder, M. and Schmitt, C.A. and Vallet, S. and Melchardt, T. and Zebisch, A. and Pichler, P. and Zaborsky, N. and Machherndl-Spandl, S. and Wolf, D. and Keil, F. and Hasenauer, J. and Larcher-Senn, J. and Greil, R.
American Journal of Hematology 98 (11): 1685-1698. November 2023

Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Li, X. and Wu, F. and Günther, S. and Looso, M. and Kuenne, C. and Zhang, T. and Wiesnet, M. and Klatt, S. and Zukunft, S. and Fleming, I. and Poschet, G. and Wietelmann, A. and Atzberger, A. and Potente, M. and Yuan, X. and Braun, T.
Nature 622 (7983): 619-626. 19 October 2023

Hippocampal GABAergic interneurons and memory.
Tzilivaki, A. and Tukker, J.J. and Maier, N. and Poirazi, P. and Sammons, R.P. and Schmitz, D.
Neuron 111 (20): 3154-3175. 18 October 2023

Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR.
Balyschew, N. and Yushkevich, A. and Mikirtumov, V. and Sanchez, R.M. and Sprink, T. and Kudryashev, M.
Nature Communications 14 (1): 6543. 17 October 2023

Molecular basis of ClC-6 function and its impairment in human disease.
Zhang, B. and Zhang, S. and Polovitskaya, M.M. and Yi, J. and Ye, B. and Li, R. and Huang, X. and Yin, J. and Neuens, S. and Balfroid, T. and Soblet, J. and Vens, D. and Aeby, A. and Li, X. and Cai, J. and Song, Y. and Li, Y. and Tartaglia, M. and Li, Y. and Jentsch, T.J. and Yang, M. and Liu, Z.
Science Advances 9 (41): eadg4479. 13 October 2023

Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.
Nurminen, A. and Jaatinen, S. and Taavitsainen, S. and Högnäs, G. and Lesluyes, T. and Ansari-Pour, N. and Tolonen, T. and Haase, K. and Koskenalho, A. and Kankainen, M. and Jasu, J. and Rauhala, H. and Kesäniemi, J. and Nikupaavola, T. and Kujala, P. and Rinta-Kiikka, I. and Riikonen, J. and Kaipia, A. and Murtola, T. and Tammela, T.L. and Visakorpi, T. and Nykter, M. and Wedge, D.C. and Van Loo, P. and Bova, G.S.
Genome Medicine 15 (1): 82. 12 October 2023

Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly.
Rizalar, F.S. and Lucht, M.T. and Petzoldt, A. and Kong, S. and Sun, J. and Vines, J.H. and Telugu, N.S. and Diecke, S. and Kaas, T. and Bullmann, T. and Schmied, C. and Löwe, D. and King, J.S. and Cho, W. and Hallermann, S. and Puchkov, D. and Sigrist, S.J. and Haucke, V.
Science 382 (6667): 223-230. 12 October 2023

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Budu-Aggrey, A. and Kilanowski, A. and Sobczyk, M.K. and Shringarpure, S.S. and Mitchell, R. and Reis, K. and Reigo, A. and Mägi, R. and Nelis, M. and Tanaka, N. and Brumpton, B.M. and Thomas, L.F. and Sole-Navais, P. and Flatley, C. and Espuela-Ortiz, A. and Herrera-Luis, E. and Lominchar, J.V.T. and Bork-Jensen, J. and Marenholz, I. and Arnau-Soler, A. and Jeong, A. and Fawcett, K.A. and Baurecht, H. and Rodriguez, E. and Alves, A.C. and Kumar, A. and Sleiman, P.M. and Chang, X. and Medina-Gomez, C. and Hu, C. and Xu, C.J. and Qi, C. and El-Heis, S. and Titcombe, P. and Antoun, E. and Fadista, J. and Wang, C.A. and Thiering, E. and Wu, B. and Kress, S. and Kothalawala, D.M. and Kadalayil, L. and Duan, J. and Zhang, H. and Hadebe, S. and Hoffmann, T. and Jorgenson, E. and Choquet, H. and Risch, N. and Njølstad, P. and Andreassen, O.A. and Johansson, S. and Almqvist, C. and Gong, T. and Ullemar, V. and Karlsson, R. and Magnusson, P.K.E. and Szwajda, A. and Burchard, E.G. and Thyssen, J.P. and Hansen, T. and Kårhus, L.L. and Dantoft, T.M. and Jeanrenaud, A.C.S.N. and Ghauri, A. and Arnold, A. and Homuth, G. and Lau, S. and Nöthen, M.M. and Hübner, N. and Imboden, M. and Visconti, A. and Falchi, M. and Bataille, V. and Hysi, P. and Ballardini, N. and Boomsma, D.I. and Hottenga, J.J. and Müller-Nurasyid, M. and Ahluwalia, T.S. and Stokholm, J. and Chawes, B. and Schoos, A.M.M. and Esplugues, A. and Bustamante, M. and Raby, B. and Arshad, S. and German, C. and Esko, T. and Milani, L.A. and Metspalu, A. and Terao, C. and Abuabara, K. and Løset, M. and Hveem, K. and Jacobsson, B. and Pino-Yanes, M. and Strachan, D.P. and Grarup, N. and Linneberg, A. and Lee, Y. and Probst-Hensch, N. and Weidinger, S. and Jarvelin, M.R. and Melén, E. and Hakonarson, H. and Irvine, A.D. and Jarvis, D. and Nijsten, T. and Duijts, L. and Vonk, J.M. and Koppelmann, G.H. and Godfrey, K.M. and Barton, S.J. and Feenstra, B. and Pennell, C.E. and Sly, P.D. and Holt, P.G. and Williams, L.K. and Bisgaard, H. and Bønnelykke, K. and Curtin, J. and Simpson, A. and Murray, C. and Schikowski, T. and Bunyavanich, S. and Weiss, S.T. and Holloway, J.W. and Min, J.L. and Brown, S.J. and Standl, M. and Paternoster, L.
Nature Communications 14 (1): 6172. 4 October 2023

Play and tickling responses map to the lateral columns of the rat periaqueductal gray.
Gloveli, N. and Simonnet, J. and Tang, W. and Concha-Miranda, M. and Maier, E. and Dvorzhak, A. and Schmitz, D. and Brecht, M.
Neuron 111 (19): 3041-3052. 4 October 2023

MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous, E.T. and Stolzenberg, S. and Sticht, J. and Wieczorek, M. and Roske, Y. and Günther, M. and Dähn, S. and Boesen, B.B. and Calvo, M.M. and Biese, C. and Kuppler, F. and Medina-García, Á. and Álvaro-Benito, M. and Höfer, T. and Noé, F. and Freund, C.
Nature Chemical Biology 19 (10): 1196-1204. October 2023

Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert, T. and Hsu, C.J. and Becker, A.L. and Graessle, S. and Horne, A. and Bemmann, F. and Zhang, Q. and Heuser, M. and Vasioukhin, V. and Scholl, S. and Hochhaus, A. and Siegerist, F. and Endlich, N. and Bullinger, L. and Lane, S.W. and Haas, S. and Schnoeder, T.M and Heidel, F.H.
Leukemia 37 (10): 2027-2035. October 2023

Internet-delivered cognitive behavioural therapy programme to reduce depressive symptoms in patients with multiple sclerosis: a multicentre, randomised, controlled, phase 3 trial.
Gold, S.M. and Friede, T. and Meyer, B. and Moss-Morris, R. and Hudson, J. and Asseyer, S. and Bellmann-Strobl, J. and Leisdon, A. and Ißels, L. and Ritter, K. and Schymainski, D. and Pomeroy, H. and Lynch, S.G. and Cozart, J.S. and Thelen, J. and Román, C.A.F. and Cadden, M. and Guty, E. and Lau, S. and Pöttgen, J. and Ramien, C. and Seddiq-Zai, S. and Kloidt, A.M. and Wieditz, J. and Penner, I.K. and Paul, F. and Sicotte, N.L. and Bruce, J.M. and Arnett, P.A. and Heesen, C.
Lancet Digital Health 5 (10): e668-e678. October 2023

DNA repair and antibody diversification: the 53BP1 paradigm.
Kabrani, E. and Saha, T. and Di Virgilio, M.
Trends in Immunology 44 (10): 782-791. October 2023

Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini, I. and Emmenegger, L. and Zappulo, A. and Rybak-Wolf, A. and Wurmus, R. and Oliveras Martinez, A. and Cerda Jara, C. and Boltengagen, A. and Hessler, T. and Mastrobuoni, G. and Kempa, S. and Zinzen, R. and Woehler, A. and Rajewsky, N.
Nature Methods 20 (10): 1544-1552. October 2023

Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing.
Cui, L. and Yang, B. and Xiao, S. and Gao, J. and Baud, A. and Graham, D. and McBride, M. and Dominiczak, A. and Schafer, S. and Aumatell, R.L. and Mont, C. and Teruel, A.F. and Hübner, N. and Flint, J. and Mott, R. and Huang, L.
Genome Biology 24 (1): 215. 29 September 2023

Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion.
Rejeski, K. and Perez, A. and Iacoboni, G. and Blumenberg, V. and Bücklein, V.L. and Völkl, S. and Penack, O. and Albanyan, O. and Stock, S. and Müller, F. and Karschnia, P. and Petrera, A. and Reid, K. and Faramand, R. and Davila, M.L. and Modi, K. and Dean, E.A. and Bachmeier, C. and von Bergwelt-Baildon, M. and Locke, F.L. and Bethge, W. and Bullinger, L. and Mackensen, A. and Barba, P. and Jain, M.D. and Subklewe, M.
Science Advances 9 (38): eadg3919. 22 September 2023

Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide.
Andrikopoulos, P. and Aron-Wisnewsky, J. and Chakaroun, R. and Myridakis, A. and Forslund, S.K. and Nielsen, T. and Adriouch, S. and Holmes, B. and Chilloux, J. and Vieira-Silva, S. and Falony, G. and Salem, J.E. and Andreelli, F. and Belda, E. and Kieswich, J. and Chechi, K. and Puig-Castellvi, F. and Chevalier, M. and Le Chatelier, E. and Olanipekun, M.T. and Hoyles, L. and Alves, R. and Helft, G. and Isnard, R. and Køber, L. and Coelho, L.P. and Rouault, C. and Gauguier, D. and Gøtze, J.P. and Prifti, E. and Froguel, P. and Zucker, J.D. and Bäckhed, F. and Vestergaard, H. and Hansen, T. and Oppert, J.M. and Blüher, M. and Nielsen, J. and Raes, J. and Bork, P. and Yaqoob, M.M. and Stumvoll, M. and Pedersen, O. and Ehrlich, S.D. and Clément, K. and Dumas, M.E.
Nature Communications 14 (1): 5843. 20 September 2023

Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
Monsorno, K. and Ginggen, K. and Ivanov, A. and Buckinx, A. and Lalive, A.L. and Tchenio, A. and Benson, S. and Vendrell, M. and D'Alessandro, A. and Beule, D. and Pellerin, L. and Mameli, M. and Paolicelli, R.C.
Nature Communications 14 (1): 5749. 16 September 2023

Long-read sequencing reveals extensive DNA methylations in human gut phagenome contributed by prevalently phage-encoded methyltransferases.
Sun, C. and Chen, J. and Jin, M. and Zhao, X. and Li, Y. and Dong, Y. and Gao, N. and Liu, Z. and Bork, P. and Zhao, X.M. and Chen, W.H.
Advanced Science 10 (25): 2302159. 5 September 2023

The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis.
Schoeler, M. and Ellero-Simatos, S. and Birkner, T. and Mayneris-Perxachs, J. and Olsson, L. and Brolin, H. and Löber, U. and Kraft, J.D. and Polizzi, A. and Martí-Navas, M. and Puig, J. and Moschetta, A. and Montagner, A. and Gourdy, P. and Heymes, C. and Guillou, H. and Tremaroli, V. and Fernández-Real, J.M. and Forslund, S.K. and Burcelin, R. and Caesar, R.
Nature Communications 14 (1): 5329. 1 September 2023

Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire.
Anker, M.S. and Potthoff, S.K. and Lena, A. and Porthun, J. and Hadzibegovic, S. and Evertz, R. and Denecke, C. and Fröhlich, A.K. and Sonntag, F. and Regitz-Zagrosek, V. and Rosen, S.D. and Lyon, A.R. and Lüscher, T.F. and Spertus, J.A. and Anker, S.D. and Karakas, M. and Bullinger, L. and Keller, U. and Landmesser, U. and Butler, J. and von Haehling, S.
European Journal of Heart Failure 25 (9): 1635-1647. September 2023

Potassium homeostasis - Physiology and pharmacology in a clinical context.
Kettritz, R. and Loffing, J.
Pharmacology & Therapeutics 249 : 108489. September 2023

Systematic perturbation of chromatin factors identifies regulatory networks during healthy and malignant hematopoiesis.
Solé-Boldo, L. and Haas, S.
Nature Genetics 55 (9): 1430-1431. September 2023

Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
Zhang, L. and Wirth, M. and Patra, U. and Stroh, J. and Isaakidis, K. and Rieger, L. and Kossatz, S. and Milanovic, M. and Zang, C. and Demel, U. and Keiten-Schmitz, J. and Wagner, K. and Steiger, K. and Rad, R. and Bassermann, F. and Müller, S. and Keller, U. and Schick, M.
EMBO Molecular Medicine 15 (9): e16431. September 2023

Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions.
Tschernoster, N. and Erger, F. and Kohl, S. and Reusch, B. and Wenzel, A. and Walsh, S. and Thiele, H. and Becker, C. and Franitza, M. and Bartram, M.P. and Kömhoff, M. and Schumacher, L. and Kukat, C. and Borodina, T. and Quedenau, C. and Nürnberg, P. and Rinschen, M.M. and Driller, J.H. and Pedersen, B.P. and Schlingmann, K.P. and Hüttel, B. and Bockenhauer, D. and Beck, B. and Altmüller, J.
Genome Medicine 15 (1): 62. 23 August 2023

Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.
Lluch, A. and Latorre, J. and Serena-Maione, A. and Espadas, I. and Caballano-Infantes, E. and Moreno-Navarrete, J.M. and Oliveras-Cañellas, N. and Ricart, W. and Malagón, M.M. and Martin-Montalvo, A. and Birchmeier, W. and Szymanski, W. and Graumann, J. and Gómez-Serrano, M. and Sommariva, E. and Fernández-Real, J.M. and Ortega, F.J.
Nature Communications 14 (1): 5106. 22 August 2023

Long-term symptom severity and clinical biomarkers in post-COVID-19/chronic fatigue syndrome: results from a prospective observational cohort.
Legler, F. and Meyer-Arndt, L. and Mödl, L. and Kedor, C. and Freitag, H. and Stein, E. and Hoppmann, U. and Rust, R. and Wittke, K. and Siebert, N. and Behrens, J. and Thiel, A. and Konietschke, F. and Paul, F. and Scheibenbogen, C. and Bellmann-Strobl, J.
EClinicalMedicine 63 : 102146. 19 August 2023

Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level.
John, L. and Poos, A.M. and Brobeil, A. and Schinke, C. and Huhn, S. and Prokoph, N. and Lutz, R. and Wagner, B. and Zangari, M. and Tirier, S.M. and Mallm, J.P. and Schumacher, S. and Vonficht, D. and Solé-Boldo, L. and Quick, S. and Steiger, S. and Przybilla, M.J. and Bauer, K. and Baumann, A. and Hemmer, S. and Rehnitz, C. and Lückerath, C. and Sachpekidis, C. and Mechtersheimer, G. and Haberkorn, U. and Dimitrakopoulou-Strauss, A. and Reichert, P. and Barlogie, B. and Müller-Tidow, C. and Goldschmidt, H. and Hillengass, J. and Rasche, L. and Haas, S.F. and van Rhee, F. and Rippe, K. and Raab, M.S. and Sauer, S. and Weinhold, N.
Nature Communications 14 (1): 5011. 17 August 2023

Enterotypes of the human gut mycobiome.
Lai, S. and Yan, Y. and Pu, Y. and Lin, S. and Qiu, J.G. and Jiang, B.H. and Keller, M.I. and Wang, M. and Bork, P. and Chen, W.H. and Zheng, Y. and Zhao, X.M.
Microbiome 11 (1): 179. 11 August 2023

Systematic benchmarking of single-cell ATAC-sequencing protocols.
De Rop, F.V. and Hulselmans, G. and Flerin, C. and Soler-Vila, P. and Rafels, A. and Christiaens, V. and González-Blas, C.B. and Marchese, D. and Caratù, G. and Poovathingal, S. and Rozenblatt-Rosen, O. and Slyper, M. and Luo, W. and Muus, C. and Duarte, F. and Shrestha, R. and Bagdatli, S.T. and Corces, M.R. and Mamanova, L. and Knights, A. and Meyer, K.B. and Mulqueen, R. and Taherinasab, A. and Maschmeyer, P. and Pezoldt, J. and Lambert, C.L.G. and Iglesias, M. and Najle, S.R. and Dossani, Z.Y. and Martelotto, L.G. and Burkett, Z. and Lebofsky, R. and Martin-Subero, J.I. and Pillai, S. and Sebé-Pedrós, A. and Deplancke, B. and Teichmann, S.A. and Ludwig, L.S. and Braun, T.P. and Adey, A.C. and Greenleaf, W.J. and Buenrostro, J.D. and Regev, A. and Aerts, S. and Heyn, H.
Nature Biotechnology 3 August 2023 (In Press)

mRNA stability and m(6)A are major determinants of subcellular mRNA localization in neurons.
Loedige, I. and Baranovskii, A. and Mendonsa, S. and Dantsuji, S. and Popitsch, N. and Breimann, L. and Zerna, N. and Cherepanov, V. and Milek, M. and Ameres, S. and Chekulaeva, M.
Molecular Cell 83 (15): 2709-2725. 3 August 2023

Robust phenotyping of highly multiplexed tissue imaging data using pixel-level clustering.
Liu, C.C. and Greenwald, N.F. and Kong, A. and McCaffrey, E.F. and Leow, K.X. and Mrdjen, D. and Cannon, B.J. and Rumberger, J.L. and Varra, S.R. and Angelo, M.
Nature Communications 14 (1): 4618. 1 August 2023

Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis.
Schaupp, L. and Addante, A. and Völler, M. and Fentker, K. and Kuppe, A. and Bardua, M. and Duerr, J. and Piehler, L. and Röhmel, J. and Thee, S. and Kirchner, M. and Ziehm, M. and Lauster, D. and Haag, R. and Gradzielski, M. and Stahl, M. and Mertins, P. and Boutin, S. and Graeber, S.Y. and Mall, M.A.
European Respiratory Journal 62 (2): 2202153. 1 August 2023

Cardiac splicing as a diagnostic and therapeutic target.
Gotthardt, M. and Badillo Lisakowski, V. and Parikh, V.N. and Ashley, E. and Furtado, M. and Carmo-Fonseca, M. and Schudy, S. and Meder, B. and Grosch, M. and Steinmetz, L. and Crocini, C. and Leinwand, L.
Nature Reviews Cardiology 20 (8): 517-530. August 2023

Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia.
Kayser, S. and Martínez-Cuadrón, D. and Rodriguez-Veiga, R. and Hänel, M. and Tormo, M. and Schäfer-Eckart, K. and Botella, C. and Stölzel, F. and Del Castillo, T.B. and Keller, U. and Rodriguez-Medina, C. and Held, G. and Amigo, M.L. and Schliemann, C. and Colorado, M. and Kaufmann, M. and Garcia, M.B. and Krause, S.W. and Görner, M. and Jost, E. and Steffen, B. and Zukunft, S. and Platzbecker, U. and Ho, A.D. and Baldus, C.D. and Serve, H. and Müller-Tidow, C. and Thiede, C. and Bornhäuser, M. and Montesinos, P. and Röllig, C. and Schlenk, R.F.
Haematologica 108 (8): 2059-2066. August 2023

Intravenous immunoglobulin treatment for acute attacks in myelin oligodendrocyte glycoprotein antibody disease.
Lotan, I. and Chen, J.J. and Hacohen, Y. and Abdel-Mannan, O. and Mariotto, S. and Huda, S. and Gibbons, E. and Wilf-Yarkoni, A. and Hellmann, M.A. and Stiebel-Kalish, H. and Pittock, S.J. and Flanagan, E.P. and Molazadeh, N. and Anderson, M. and Salky, R. and Romanow, G. and Schindler, P. and Duchow, A.S. and Paul, F. and Levy, M.
Multiple Sclerosis Journal 29 (9): 1080-1089. August 2023

Comments on the myPACE randomized clinical trial.
Rodolico, D. and Schiattarella, G.G.
JAMA Cardiology 8 (8): 794-795. August 2023

Transgenic angiotensin-converting enzyme 2 overexpression in the rat vasculature protects kidneys from ageing-induced injury.
Sanad, A.M. and Qadri, F. and Popova, E. and Rodrigues, A.F. and Heinbokel, T. and Quach, S. and Schulz, A. and Bachmann, S. and Kreutz, R. and Alenina, N. and Bader, M.
Kidney International 104 (2): 293-304. August 2023

Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A. and Walter, S. and Markó, L. and McMurray, B.J. and Sunaga-Franze, D.Y. and Xu, M. and Zühlke, K. and Russwurm, M. and Bartolomaeus, T.U.P. and Langanki, R. and Qadri, F. and Heuser, A. and Patzak, A. and Forslund, S.K. and Bähring, S. and Borodina, T. and Persson, P.B. and Maass, P.G. and Bader, M. and Klussmann, E.
Kidney International 104 (2): 388-393. August 2023

Spatially resolved multiomics of human cardiac niches.
Kanemaru, K. and Cranley, J. and Muraro, D. and Miranda, A.M.A. and Ho, S.Y. and Wilbrey-Clark, A. and Patrick Pett, J. and Polanski, K. and Richardson, L. and Litvinukova, M. and Kumasaka, R. and Qin, Y. and Jablonska, Z. and Semprich, C.I. and Mach, L. and Dabrowska, M. and Richoz, R. and Bolt, L. and Mamanova, L. and Kapuge, R. and Barnett, S.N. and Perera, S. and Talavera-López, C. and Mulas, I. and Mahbubani, K.T. and Tuck, Liz and Wang, Lu and Huang, M.M. and Prete, M. and Pritchard, S. and Dark, J. and Saeb-Parsy, K. and Patel, M. and Clatworthy, M.R. and Hübner, N. and Chowdhury, R.A. and Noseda, M. and Teichmann, S.A.
Nature 619 : 801-810. 27 July 2023

Treatment of adult ALL patients with third-generation CD19-directed CAR T cells: results of a pivotal trial.
Schubert, M.L. and Schmitt, A. and Hückelhoven-Krauss, A. and Neuber, B. and Kunz, A. and Waldhoff, P. and Vonficht, D. and Yousefian, S. and Jopp-Saile, L. and Wang, L. and Korell, F. and Keib, A. and Michels, B. and Haas, D. and Sauer, T. and Derigs, P. and Kulozik, A. and Kunz, J. and Pavel, P. and Laier, S. and Wuchter, P. and Schmier, J. and Bug, G. and Lang, F. and Gökbuget, N. and Casper, J. and Görner, M. and Finke, J. and Neubauer, A. and Ringhoffer, M. and Wolleschak, D. and Brüggemann, M. and Haas, S. and Ho, A.D. and Müller-Tidow, C. and Dreger, P. and Schmitt, M.
Journal of Hematology & Oncology 16 (1): 79. 22 July 2023

Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
Ziegler, K.A. and Ahles, A. and Dueck, A. and Esfandyari, D. and Pichler, P. and Weber, K. and Kotschi, S. and Bartelt, A. and Sinicina, I. and Graw, M. and Leonhardt, H. and Weckbach, L.T. and Massberg, S. and Schifferer, M. and Simons, M. and Hoeher, L. and Luo, J. and Ertürk, A. and Schiattarella, G.G. and Sassi, Y. and Misgeld, T. and Engelhardt, S.
Science 381 (6655): 285-290. 21 July 2023

A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A. and Haenig, C. and Neuendorf, N. and Blanc, E. and Ivanov, A. and Kirchner, M. and Schleumann, P. and Bayraktaroğlu, I. and Richter, M. and Molenda, C.M. and Sporbert, A. and Zenkner, M. and Schnoegl, S. and Suenkel, C. and Schneider, L.S. and Rybak-Wolf, A. and Kochnowsky, B. and Byrne, L.M. and Wild, E.J. and Nielsen, J.E. and Dittmar, G. and Peters, O. and Beule, D. and Wanker, E.E.
Genome Medicine 15 (1): 50. 20 July 2023

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
Lowenstein, E.D. and Ruffault, P.L. and Misios, A. and Osman, K.L. and Li, H. and Greenberg, R.S. and Thompson, R. and Song, K. and Dietrich, S. and Li, X. and Vladimirov, N. and Woehler, A. and Brunet, J.F. and Zampieri, N. and Kühn, R. and Liberles, S.D. and Jia, S. and Lewin, G.R. and Rajewsky, N. and Lever, T.E. and Birchmeier, C.
Neuron 111 (14): 2184-2200.e7. 19 July 2023

Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3.
Kornienko, J. and Rodríguez-Martínez, M. and Fenzl, K. and Hinze, F. and Schraivogel, D. and Grosch, M. and Tunaj, B. and Lindenhofer, D. and Schraft, L. and Kueblbeck, M. and Smith, E. and Mao, C. and Brown, E. and Owens, A. and Saguner, A.M. and Meder, B. and Parikh, V. and Gotthardt, M. and Steinmetz, L.M.
Nature Communications 14 (1): 4312. 18 July 2023

Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH.
Singh, M. and Kondraskhina, A.M. and Hurst, L.D. and Izsvák, Z.
Journal of Clinical Investigation 133 (14): e172278. 17 July 2023

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
Yeh, Y.T. and Sona, C. and Yan, X. and Li, Y. and Pathak, A. and McDermott, M.I. and Xie, Z. and Liu, L. and Arunagiri, A. and Wang, Y. and Cazenave-Gassiot, A. and Ghosh, A. and von Meyenn, F. and Kumarasamy, S. and Najjar, S.M. and Jia, S. and Wenk, M.R. and Traynor-Kaplan, A. and Arvan, P. and Barg, S. and Bankaitis, V.A. and Poy, M.N.
Nature Communications 14 (1): 4250. 17 July 2023

An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
Griger, J. and Widholz, S.A. and Jesinghaus, M. and de Andrade Krätzig, N. and Lange, S. and Engleitner, T. and Montero, J.J. and Zhigalova, E. and Öllinger, R. and Suresh, V. and Winkler, W. and Lier, S. and Baranov, O. and Trozzo, R. and Ben Khaled, N. and Chakraborty, S. and Yu, J. and Konukiewitz, B. and Steiger, K. and Pfarr, N. and Rajput, A. and Sailer, D. and Keller, G. and Schirmacher, P. and Röcken, C. and Fagerstedt, K.W. and Mayerle, J. and Schmidt-Supprian, M. and Schneider, G. and Weichert, W. and Calado, D.P. and Sommermann, T. and Klöppel, G. and Rajewsky, K. and Saur, D. and Rad, R.
Cancer Cell 41 (7): 1327-1344.e10. 10 July 2023

Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis.
Harnack, C. and Berger, H. and Liu, L. and Mollenkopf, H.J. and Strowig, T. and Sigal, M.
Gut Microbes 15 (1): 2233689. 10 July 2023

Regulation of developmental tempo in different vertebrate species.
Birchmeier, C.
Cell Stem Cell 30 (7): 907-908. 6 July 2023

Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang, Q. and Stachelscheid, J. and Bloehdorn, J. and Pacholewska, A. and Aszyk, C.M. and Grotenhuijs, F. and Müller, T.A. and Onder, O. and Wagle, P. and Herling, C.D. and Kleppe, M. and Wang, Z. and Coombes, K.R. and Robrecht, S. and Dalvi, P.S. and Plosnita, B. and Mayer, P. and Abruzzo, L.V. and Altmüller, J. and Gathof, B.S. and Persigehl, T. and Fischer, K. and Jebaraj, B.M.C. and Rienhoff, H.Y. and Ecker, R.C. and Zhao, Y. and Bruns, C.J. and Stilgenbauer, S. and Elenitoba-Johnson, K.S.J. and Hallek, M. and Schweiger, M.R. and Odenthal, M. and Vasyutina, E. and Herling, M.
Blood 142 (1): 44-61. 6 July 2023

A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals.
Lázaro, J. and Costanzo, M. and Sanaki-Matsumiya, M. and Girardot, C. and Hayashi, M. and Hayashi, K. and Diecke, S. and Hildebrandt, T.B. and Lazzari, G. and Wu, J. and Petkov, S. and Behr, R. and Trivedi, V. and Matsuda, M. and Ebisuya, M.
Cell Stem Cell 30 (7): 938-949.e7. 6 July 2023

Towards monitoring of antimicrobial resistance in the environment: For what reasons, how to implement it, and what are the data needs?
Bengtsson-Palme, J. and Abramova, A. and Berendonk, T.U. and Coelho, L.P. and Forslund, S.K. and Gschwind, R. and Heikinheimo, A. and Jarquín-Díaz, V.H. and Khan, A.A. and Klümper, U. and Löber, U. and Nekoro, M. and Osińska, A.D. and Ugarcina Perovic, S. and Pitkänen, T. and Rødland, E.K. and Ruppé, E. and Wasteson, Y. and Wester, A.L. and Zahra, R.
Environment International 178 : 108089. 5 July 2023

e-RNA: a collection of web-servers for the prediction and visualisation of RNA secondary structure and their functional features.
Tsybulskyi, V. and Semenchenko, E. and Meyer, I.M.
Nucleic Acids Research 51 (W1): W160-W167. 5 July 2023

Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S. and Danßmann, C. and Klironomos, F. and Winkler, A. and Fallmann, J. and Kruetzfeldt, L.M. and Szymansky, A. and Naderi, J. and Bernhart, S.H. and Grunewald, L. and Helmsauer, K. and Rodriguez-Fos, E. and Kirchner, M. and Mertins, P. and Astrahantseff, K. and Suenkel, C. and Toedling, J. and Meggetto, F. and Remke, M. and Stadler, P.F. and Hundsdoerfer, P. and Deubzer, H.E. and Künkele, A. and Lang, P. and Fuchs, J. and Henssen, A.G. and Eggert, A. and Rajewsky, N. and Hertwig, F. and Schulte, J.H.
Nature Communications 14 (1): 3936. 4 July 2023

VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats.
Samuelsson, A.M. and Bartolomaeus, T.U.P. and Anandakumar, H. and Thowsen, I. and Nikpey, E. and Han, J. and Marko, L. and Finne, K. and Tenstad, O. and Eckstein, J. and Berndt, N. and Kühne, T. and Kedziora, S. and Sultan, I. and Skogstrand, T. and Karlsen, T.V. and Nurmi, H. and Forslund, S.K. and Bollano, E. and Alitalo, K. and Muller, D.N. and Wiig, H.
Cardiovascular Research 119 (7): 1553-1567. 4 July 2023

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J. and Muinjonov, B. and Rosiewicz, K.S. and Diecke, S. and Biese, C. and Schiweck, J. and Chien, C. and Zocholl, D. and Conrad, T. and Paul, F. and Alisch, M. and Siffrin, V.
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C.
Beagrie, R.A. and Thieme, C.J. and Annunziatella, C. and Baugher, C. and Zhang, Y. and Schueler, M. and Kukalev, A. and Kempfer, R. and Chiariello, A.M. and Bianco, S. and Li, Y. and Davis, T. and Scialdone, A. and Welch, L.R. and Nicodemi, M. and Pombo, A.
Nature Methods 20 (7): 1037-1047. July 2023

Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M. and Terkelsen, T. and Bartels, A.S. and Coscia, F. and Doll, S. and Zhao, S. and Zhang, Z. and Brünner, N. and Lindebjerg, J. and Madsen, G.I. and Fang, X. and Mann, M. and Moreira, J.M.A.
Gastroenterology 165 (1): 121-132.e5. July 2023

Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
Döhner, H. and Weber, D. and Krzykalla, J. and Fiedler, W. and Kühn, M.W.M. and Schroeder, T. and Mayer, K. and Lübbert, M. and Wattad, M. and Götze, K. and Fransecky, L. and Koller, E. and Wulf, G. and Schleicher, J. and Ringhoffer, M. and Greil, R. and Hertenstein, B. and Krauter, J. and Martens, U.M. and Nachbaur, D. and Samra, M.A. and Machherndl-Spandl, S. and Basara, N. and Leis, C. and Schrade, A. and Kapp-Schwoerer, S. and Cocciardi, S. and Bullinger, L. and Thol, F. and Heuser, M. and Paschka, P. and Gaidzik, V.I. and Saadati, M. and Benner, A. and Schlenk, R.F. and Döhner, K. and Ganser, A.
Lancet Haematology 10 (7): e495-e509. July 2023

Sex-specific microglia state in the neuroligin-4 knock-out mouse model of autism spectrum disorder.
Guneykaya, D. and Ugursu, B. and Logiacco, F. and Popp, O. and Feiks, M.A. and Meyer, N. and Wendt, S. and Semtner, M. and Cherif, F. and Gauthier, C. and Madore, C. and Yin, Z. and Çınar, Ö. and Arslan, T. and Gerevich, Z. and Mertins, P. and Butovsky, O. and Kettenmann, H. and Wolf, S.A.
Brain Behavior and Immunity 111 : 61-75. July 2023

Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.
Lareau, C.A. and Dubois, S.M. and Buquicchio, F.A. and Hsieh, Y.H. and Garg, K. and Kautz, P. and Nitsch, L. and Praktiknjo, S.D. and Maschmeyer, P. and Verboon, J.M. and Gutierrez, J.C. and Yin, Y. and Fiskin, E. and Luo, W. and Mimitou, E.P. and Muus, C. and Malhotra, R. and Parikh, S. and Fleming, M.D. and Oevermann, L. and Schulte, J. and Eckert, C. and Kundaje, A. and Smibert, P. and Vardhana, S.A. and Satpathy, A.T. and Regev, A. and Sankaran, V.G. and Agarwal, S. and Ludwig, L.S.
Nature Genetics 55 (7): 1198-1209. July 2023

Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.
Rybak-Wolf, A. and Wyler, E. and Pentimalli, T.M. and Legnini, I. and Oliveras Martinez, A. and Glažar, P. and Loewa, A. and Kim, S.J. and Kaufer, B.B. and Woehler, A. and Landthaler, M. and Rajewsky, N.
Nature Microbiology 8 (7): 1252-1266. July 2023

Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury.
Sieckmann, T. and Schley, G. and Ögel, N. and Kelterborn, S. and Boivin, F.J. and Fähling, M. and Ashraf, M.I. and Reichel, M. and Vigolo, E. and Hartner, A. and Lichtenberger, F.B. and Breiderhoff, T. and Knauf, F. and Rosenberger, C. and Aigner, F. and Schmidt-Ott, K. and Scholz, H. and Kirschner, K.M.
Kidney International 104 (1): 90-107. July 2023

Genome architecture mapping detects transcriptionally active, multiway chromatin contacts.
Thieme, C.J. and Pombo, A.
Nature Methods 20 (7): 993-994. July 2023

The DNA methylation status of the TERT promoter differs between subtypes of mature B-cell lymphomas.
Kouroukli, A.G. and Fischer, A. and Kretzmer, H. and Chteinberg, E. and Rajaram, N. and Glaser, S. and Kolarova, J. and Bashtrykov, P. and Mathas, S. and Drexler, H.G. and Ohno, H. and Ammerpohl, O. and Jeltsch, A. and Siebert, R. and Bens, S.
Blood Cancer Journal 13 (1): 98. 26 June 2023

Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses.
Jiang, B. and Schmitt, M.J. and Rand, U. and Company, C. and Dramaretska, Y. and Grossmann, M. and Serresi, M. and Cicin-Sain, L. and Gargiulo, G.
Science Advances 9 (25): eadf4975. 23 June 2023

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.
Milenkovic, I. and Santos Vieira, H.G. and Lucas, M.C. and Ruiz-Orera, J. and Patone, G. and Kesteven, S. and Wu, J. and Feneley, M. and Espadas, G. and Sabidó, E. and Hübner, N. and van Heesch, S. and Völkers, M. and Novoa, E.M.
Nucleic Acids Research 51 (11): 5301-5324. 23 June 2023

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy.
Grosch, M. and Schraft, L. and Chan, A. and Küchenhoff, L. and Rapti, K. and Ferreira, A.M. and Kornienko, J. and Li, S. and Radke, M.H. and Krämer, C. and Clauder-Münster, S. and Perlas, E. and Backs, J. and Gotthardt, M. and Dieterich, C. and van den Hoogenhof, M.M.G. and Grimm, D. and Steinmetz, L.M.
Nature Communications 14 (1): 3714. 22 June 2023

Transcription factor induction of vascular blood stem cell niches in vivo.
Hagedorn, E.J. and Perlin, J.R. and Freeman, R.J. and Wattrus, S.J. and Han, T. and Mao, C. and Kim, J.W. and Fernández-Maestre, I. and Daily, M.L. and D'Amato, C. and Fairchild, M.J. and Riquelme, R. and Li, B. and Ragoonanan, D.A.V.E. and Enkhbayar, K. and Henault, E.L. and Wang, H.G. and Redfield, S.E. and Collins, S.H. and Lichtig, A. and Yang, S. and Zhou, Y. and Kunar, B. and Gomez-Salinero, J.M. and Dinh, T.T. and Pan, J. and Holler, K. and Feldman, H.A. and Butcher, E.C. and van Oudenaarden, A. and Rafii, S. and Junker, J.P. and Zon, L.I.
Developmental Cell 58 (12): 1037-1051. 19 June 2023

Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors.
Bonifacius, A. and Lamottke, B. and Tischer-Zimmermann, S. and Schultze-Florey, R. and Goudeva, L. and Heuft, H.G. and Arseniev, L. and Beier, R. and Beutel, G. and Cario, G. and Fröhlich, B. and Greil, J. and Hansmann, L. and Hasenkamp, J. and Höfs, M. and Hundsdoerfer, P. and Jost, E. and Kafa, K. and Kriege, O. and Kröger, N. and Mathas, S. and Meisel, R. and Nathrath, M. and Putkonen, M. and Ravens, S. and Reinhardt, H.C. and Sala, E. and Sauer, M.G and Schmitt, C. and Schroers, R. and Steckel, N.K. and Trappe, R.U. and Verbeek, M. and Wolff, D. and Blasczyk, R. and Eiz-Vesper, B. and Maecker-Kolhoff, B.
Journal of Clinical Investigation 133 (12): e163548. 15 June 2023

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P. and Orgeur, M. and Comai, G. and Poehle-Kronnawitter, S. and Fischer, C. and Gloger, M. and Dumas, C.E. and Giesecke-Thiel, C. and Sauer, S. and Tajbakhsh, S. and Höpken, U.E. and Stricker, S.
Immunity 56 (6): 1204-1219. 13 June 2023

Evolution and implications of de novo genes in humans.
Broeils, L.A. and Ruiz-Orera, J. and Snel, B. and Hubner, N. and van Heesch, S.
Nature Ecology & Evolution 7 (6): 804-815. June 2023

Functional analysis of structural variants in single cells using Strand-seq.
Jeong, H. and Grimes, K. and Rauwolf, K.K. and Bruch, P.M. and Rausch, T. and Hasenfeld, P. and Benito, E. and Roider, T. and Sabarinathan, R. and Porubsky, D. and Herbst, S.A. and Erarslan-Uysal, B. and Jann, J.C. and Marschall, T. and Nowak, D. and Bourquin, J.P. and Kulozik, A.E. and Dietrich, S. and Bornhauser, B. and Sanders, A.D. and Korbel, J.O.
Nature Biotechnology 41 (6): 832-844. June 2023

Salt sensitivity includes effects on immune cell signalling and metabolism.
Müller, D.N. and Geisberger, S. and Kleinewietfeld, M. and Jantsch, J.
Nature Reviews Immunology 23 (6): 341-342. June 2023

Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease.
Piwecka, M. and Rajewsky, N. and Rybak-Wolf, A.
Nature Reviews Neurology 19 (6): 346–362. June 2023

The lure of cardiac metabolism in the diagnosis, prevention, and treatment of heart failure.
Rodolico, D. and Schiattarella, G.G. and Taegtmeyer, H.
JACC: Heart Failure 11 (6): 637-645. June 2023

Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.
Wang, G. and Chiou, J. and Zeng, C. and Miller, M. and Matta, I. and Han, J.Y. and Kadakia, N. and Okino, M.L. and Beebe, E. and Mallick, M. and Camunas-Soler, J. and Dos Santos, T. and Dai, X.Q. and Ellis, C. and Hang, Y. and Kim, S.K. and MacDonald, P.E. and Kandeel, F.R. and Preissl, S. and Gaulton, K.J. and Sander, M.
Nature Genetics 55 (6): 984-994. June 2023

Germline C1GALT1C1 mutation causes a multisystem chaperonopathy.
Erger, F. and Aryal, R.P. and Reusch, B. and Matsumoto, Y. and Meyer, R. and Zeng, J. and Knopp, C. and Noel, M. and Muerner, L. and Wenzel, A. and Kohl, S. and Tschernoster, N. and Rappl, G. and Rouvet, I. and Schröder-Braunstein, J. and Seibert, F.S. and Thiele, H. and Häusler, M.G. and Weber, L.T. and Büttner-Herold, M. and Elbracht, M. and Cummings, S.F. and Altmüller, J. and Habbig, S. and Cummings, R.D. and Beck, B.B.
Proceedings of the National Academy of Sciences of the United States of America 120 (22): e2211087120. 30 May 2023

Sites of transcription initiation drive mRNA isoform selection.
Alfonso-Gonzalez, C. and Legnini, I. and Holec, S. and Arrigoni, L. and Ozbulut, H.C. and Mateos, F. and Koppstein, D. and Rybak-Wolf, A. and Bönisch, U. and Rajewsky, N. and Hilgers, V.
Cell 186 (11): 2438-2455. 25 May 2023

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M. and Hartl, K. and Heuberger, J. and Beccaceci, G. and Berger, H. and Li, H. and Liu, L. and Müllerke, S. and Conrad, T. and Heymann, F. and Woehler, A. and Tacke, F. and Rajewsky, N. and Sigal, M.
Nature Communications 14 (1): 3025. 25 May 2023

Analysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort.
Haueise, T. and Schick, F. and Stefan, N. and Schlett, C.L. and Weiss, J.B. and Nattenmüller, J. and Göbel-Guéniot, K. and Norajitra, T. and Nonnenmacher, T. and Kauczor, H.U. and Maier-Hein, K.H. and Niendorf, T. and Pischon, T. and Jöckel, K.H. and Umutlu, L. and Peters, A. and Rospleszcz, S. and Kröncke, T. and Hosten, N. and Völzke, H. and Krist, L. and Willich, S.N. and Bamberg, F. and Machann, J.
Science Advances 9 (19): eadd0433. 12 May 2023

Recombination between heterologous human acrocentric chromosomes.
Guarracino, A. and Buonaiuto, S. and de Lima, L.G. and Potapova, T. and Rhie, A. and Koren, S. and Rubinstein, B. and Fischer, C. and Gerton, J.L. and Phillippy, A.M. and Colonna, V. and Garrison, E.
Nature 617 (7960): 335-343. 11 May 2023

A draft human pangenome reference.
Liao, W.W. and Asri, M. and Ebler, J. and Doerr, D. and Haukness, M. and Hickey, G. and Lu, S. and Lucas, J.K. and Monlong, J. and Abel, H.J. and Buonaiuto, S. and Chang, X.H. and Cheng, H. and Chu, J. and Colonna, V. and Eizenga, J.M. and Feng, X. and Fischer, C. and Fulton, R.S. and Garg, S. and Groza, C. and Guarracino, A. and Harvey, W.T. and Heumos, S. and Howe, K. and Jain, M. and Lu, T.Y. and Markello, C. and Martin, F.J. and Mitchell, M.W. and Munson, K.M. and Mwaniki, M.N. and Novak, A.M. and Olsen, H.E. and Pesout, T. and Porubsky, D. and Prins, P. and Sibbesen, J.A. and Sirén, J. and Tomlinson, C. and Villani, F. and Vollger, M.R. and Antonacci-Fulton, L.L. and Baid, G. and Baker, C.A. and Belyaeva, A. and Billis, K. and Carroll, A. and Chang, P.C. and Cody, S. and Cook, D.E. and Cook-Deegan, R.M. and Cornejo, O.E. and Diekhans, M. and Ebert, P. and Fairley, S. and Fedrigo, O. and Felsenfeld, A.L. and Formenti, G. and Frankish, A. and Gao, Yan and Garrison, N.A. and Giron, C.G. and Green, R.E. and Haggerty, L. and Hoekzema, K. and Hourlier, T. and Ji, H.P. and Kenny, E.E. and Koenig, B.A. and Kolesnikov, A. and Korbel, J.O. and Kordosky, J. and Koren, S. and Lee, H.J. and Lewis, A.P. and Magalhães, H. and Marco-Sola, S. and Marijon, P. and McCartney, A. and McDaniel, J. and Mountcastle, J. and Nattestad, M. and Nurk, S. and Olson, N.D. and Popejoy, A.B. and Puiu, D. and Rautiainen, M. and Regier, A.A. and Rhie, A. and Sacco, S. and Sanders, A.D. and Schneider, V.A. and Schultz, B.I. and Shafin, K. and Smith, M.W. and Sofia, H.J. and Abou Tayoun, A.N. and Thibaud-Nissen, F. and Tricomi, F.F. and Wagner, J. and Walenz, B. and Wood, J.M.D. and Zimin, A.V. and Bourque, G. and Chaisson, M.J P and Flicek, Paul and Phillippy, A.M. and Zook, J.M. and Eichler, E.E. and Haussler, D. and Wang, T. and Jarvis, E.D. and Miga, K.H. and Garrison, E. and Marschall, T. and Hall, I.M. and Li, H. and Paten, B.
Nature 617 (7960): 312-324. 11 May 2023

Increased mutation and gene conversion within human segmental duplications.
Vollger, M.R. and Dishuck, P.C. and Harvey, W.T. and DeWitt, W.S. and Guitart, X. and Goldberg, M.E. and Rozanski, A.N. and Lucas, J. and Asri, M. and Munson, K.M. and Lewis, A.P. and Hoekzema, K. and Logsdon, G.A. and Porubsky, D. and Paten, B. and Harris, K. and Hsieh, P.H. and Eichler, E.E.
Nature 617 (7960): 325-334. 11 May 2023

Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia.
Beneyto-Calabuig, S. and Merbach, A.K. and Kniffka, J.A. and Antes, M. and Szu-Tu, C. and Rohde, C. and Waclawiczek, A. and Stelmach, P. and Gräßle, S. and Pervan, P. and Janssen, M. and Landry, J.J.M. and Benes, V. and Jauch, A. and Brough, M. and Bauer, M. and Besenbeck, B. and Felden, J. and Bäumer, S. and Hundemer, M. and Sauer, T. and Pabst, C. and Wickenhauser, C. and Angenendt, L. and Schliemann, C. and Trumpp, A. and Haas, S. and Scherer, M. and Raffel, S. and Müller-Tidow, C. and Velten, L.
Cell Stem Cell 30 (5): 706-721. 4 May 2023

Interferon-γ drives macrophage reprogramming, cerebrovascular remodeling, and cognitive dysfunction in a zebrafish and a mouse model of ion imbalance and pressure overload.
Apaydin, D.C. and Zakarauskas-Seth, B.I. and Carnevale, L. and Apaydin, O. and Perrotta, M. and Carnevale, R. and Kotini, M.P. and Kotlar-Goldaper, I. and Belting, H.G. and Carnevale, D. and Filosa, A. and Sawamiphak, S.
Cardiovascular research 119 (5): 1234-1249. May 2023

Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G. and Bartolomaeus, H. and Rauch, A. and Chen, C.Y. and N'Diaye, G. and Löber, U. and Bartolomaeus, T.U.P. and Fritsche-Guenther, R. and Rodrigues, A.F. and Yarritu, A. and Zhong, C. and Fei, L. and Tsvetkov, D. and Todiras, M. and Park, J.K. and Markó, L. and Maifeld, A. and Patzak, A. and Bader, M. and Kempa, S. and Kirwan, J.A. and Forslund, S.K. and Müller, D.N. and Wilck, N.
Cardiovascular Research 119 (6): 1441-1452. May 2023

Autoantibodies targeting G protein-coupled receptors: an evolving history in autoimmunity. Report of the 4th international symposium.
Cabral-Marques, O. and Moll, G. and Catar, R. and Preuß, B. and Bankamp, L. and Pecher, A.C. and Henes, J. and Klein, R. and Kamalanathan, A.S. and Akbarzadeh, R. and van Oostveen, W. and Hohberger, B. and Endres, M. and Koolmoes, B. and Levarht, N. and Postma, R. and van Duinen, V. and van Zonneveld, A.J. and de Vries-Bouwstra, J. and Fehres, C. and Tran, F. and do Vale, F.Y.N. and da Silva Souza, K.B. and Filgueiras, I.S. and Schimke, L.F. and Baiocchi, G.C. and de Miranda, G.C. and da Fonseca, D.L.M. and Freire, P.P. and Hackel, A.M. and Grasshoff, H. and Stähle, A. and Müller, A. and Dechend, R. and Yu, X. and Petersen, F. and Sotzny, F. and Sakmar, T.P. and Ochs, H.D and Schulze-Forster, Kai and Heidecke, H. and Scheibenbogen, C. and Shoenfeld, Y. and Riemekasten, G.
Autoimmunity Reviews 22 (5): 103310. May 2023

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R. and Conrad, T. and Stöber, M.C. and Xu, R. and Giurgiu, M. and Rodriguez-Fos, E. and Kasack, K. and Brückner, L. and van Leen, E. and Helmsauer, K. and Dorado Garcia, H. and Stefanova, M.E. and Hung, K.L. and Bei, Y. and Schmelz, K. and Lodrini, M. and Mundlos, S. and Chang, H.Y. and Deubzer, H.E. and Sauer, S. and Eggert, A. and Schulte, J.H. and Schwarz, R.F. and Haase, K. and Koche, R.P. and Henssen, A.G.
Nature Genetics 55 (5): 880-890. May 2023

Disentangling extrachromosomal circular DNA heterogeneity in single cells with scEC&T-seq.
Chamorro González, R. and Henssen, A.G.
Nature Genetics 55 (5): 740-741. May 2023

Parallel in-depth analysis of repeat expansions in ataxia patients by long-read sequencing.
Erdmann, H. and Schöberl, F. and Giurgiu, M. and Leal Silva, R.M. and Scholz, V. and Scharf, F. and Wendlandt, M. and Kleinle, S. and Deschauer, M. and Nübling, G. and Heide, W. and Babacan, S.S. and Schneider, C. and Neuhann, T. and Hahn, K. and Schoser, B. and Holinski-Feder, E. and Wolf, D.A. and Abicht, A.
Brain 146 (5): 1831-1843. May 2023

Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility.
Lareau, C.A. and Liu, V. and Muus, C. and Praktiknjo, S.D. and Nitsch, L. and Kautz, P. and Sandor, K. and Yin, Y. and Gutierrez, J.C. and Pelka, K. and Satpathy, A.T. and Regev, A. and Sankaran, V.G. and Ludwig, L.S.
Nature Protocols 18 (5): 1416-1440. May 2023

Single-cell transcriptomics for the assessment of cardiac disease.
Miranda, A.M.A. and Janbandhu, V. and Maatz, H. and Kanemaru, K. and Cranley, J. and Teichmann, S.A. and Huebner, N. and Schneider, M.D. and Harvey, R.P. and Noseda, M.
Nature Reviews Cardiology 20 (5): 289-308. May 2023

Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters.
Nouailles, G. and Adler, J.M. and Pennitz, P. and Peidli, S. and Teixeira Alves, L.G. and Baumgardt, M. and Bushe, J. and Voss, A. and Langenhagen, A. and Langner, C. and Martin Vidal, R. and Pott, F. and Kazmierski, J. and Ebenig, A. and Lange, M.V. and Mühlebach, M.D. and Goekeri, C. and Simmons, S. and Xing, N. and Abdelgawad, A. and Herwig, S. and Cichon, G. and Niemeyer, D. and Drosten, C. and Goffinet, C. and Landthaler, M. and Blüthgen, N. and Wu, H. and Witzenrath, M. and Gruber, A.D. and Praktiknjo, S.D. and Osterrieder, N. and Wyler, E. and Kunec, D. and Trimpert, J.
Nature Microbiology 8 (5): 860-874. May 2023

Gut microbiome and atrial fibrillation - results from a large population-based study.
Palmu, J. and Börschel, C.S. and Ortega-Alonso, A. and Markó, L. and Inouye, M. and Jousilahti, P. and Salido, R.A. and Sanders, K. and Brennan, C. and Humphrey, G.C. and Sanders, J.G. and Gutmann, F. and Linz, D. and Salomaa, V. and Havulinna, A.S. and Forslund, S.K. and Knight, R. and Lahti, L. and Niiranen, T. and Schnabel, R.B.
EBioMedicine 91 : 104583. May 2023

Inversion polymorphism in a complete human genome assembly.
Porubsky, D. and Harvey, W.T. and Rozanski, A.N. and Ebler, J. and Höps, W. and Ashraf, H. and Hasenfeld, P. and Paten, B. and Sanders, A.D. and Marschall, T. and Korbel, J.O. and Eichler, E.E.
Genome Biology 24 (1): 100. 30 April 2023

Clinical and prognostic relevance of cardiac wasting in patients with advanced cancer.
Lena, A. and Wilkenshoff, U. and Hadzibegovic, S. and Porthun, J. and Rösnick, L. and Fröhlich, A.K. and Zeller, T. and Karakas, M. and Keller, U. and Ahn, J. and Bullinger, L. and Riess, H. and Rosen, S.D. and Lyon, A.R. and Lüscher, T.F. and Totzeck, M. and Rassaf, T. and Burkhoff, D. and Mehra, M.R. and Bax, J.J. and Butler, J. and Edelmann, F. and Haverkamp, W. and Anker, S.D. and Packer, M. and Coats, A.J.S. and von Haehling, S. and Landmesser, U. and Anker, M.S.
Journal of the American College of Cardiology 81 (16): 1569-1586. 25 April 2023

TapA acts as specific chaperone in TasA filament formation by strand complementation.
Roske, Y. and Lindemann, F. and Diehl, A. and Cremer, N. and Higman, V.A. and Schlegel, B. and Leidert, M. and Driller, K. and Turgay, K. and Schmieder, P. and Heinemann, U. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 120 (17): e2217070120. 25 April 2023

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Abbosh, C. and Frankell, A.M. and Harrison, T. and Kisistok, J. and Garnett, A. and Johnson, L. and Veeriah, S. and Moreau, M. and Chesh, A. and Chaunzwa, T.L. and Weiss, J. and Schroeder, M.R. and Ward, S. and Grigoriadis, K. and Shahpurwalla, A. and Litchfield, K. and Puttick, C. and Biswas, D. and Karasaki, T. and Black, J.R.M. and Martínez-Ruiz, C. and Bakir, M.A.l. and Pich, O. and Watkins, T.B.K. and Lim, E.L. and Huebner, A. and Moore, D.A. and Godin-Heymann, N. and L'Hernault, A. and Bye, H. and Odell, A. and Roberts, P. and Gomes, F. and Patel, A.J. and Manzano, E. and Hiley, C.T. and Carey, N. and Riley, J. and Cook, D.E. and Hodgson, D. and Stetson, D. and Barrett, J.C. and Kortlever, R.M. and Evan, G.I. and Hackshaw, A. and Daber, R.D. and Shaw, J.A. and Aerts, H.J.W.L. and Licon, A. and Stahl, J. and Jamal-Hanjani, M. and Birkbak, N.J. and McGranahan, N. and Swanton, C.
Nature 616 (7957): 553-562. 20 April 2023

The evolution of lung cancer and impact of subclonal selection in TRACERx.
Frankell, A.M. and Dietzen, M. and Al Bakir, M. and Lim, E.L. and Karasaki, T. and Ward, S. and Veeriah, S. and Colliver, E. and Huebner, A. and Bunkum, A. and Hill, M.S. and Grigoriadis, K. and Moore, D.A. and Black, J.R.M. and Liu, W.K. and Thol, K. and Pich, O. and Watkins, T.B.K. and Naceur-Lombardelli, C. and Cook, D.E. and Salgado, R. and Wilson, G.A. and Bailey, C. and Angelova, M. and Bentham, R. and Martínez-Ruiz, C. and Abbosh, C. and Nicholson, A.G. and Le Quesne, J. and Biswas, D. and Rosenthal, R. and Puttick, C. and Hessey, S. and Lee, C. and Prymas, P. and Toncheva, A. and Smith, J. and Xing, W. and Nicod, J. and Price, G. and Kerr, K.M. and Naidu, B. and Middleton, G. and Blyth, K.G. and Fennell, D.A. and Forster, M.D. and Lee, S.M. and Falzon, M. and Hewish, M. and Shackcloth, M.J. and Lim, E. and Benafif, S. and Russell, P. and Boleti, E. and Krebs, M.G. and Lester, J.F. and Papadatos-Pastos, D. and Ahmad, T. and Thakrar, R.M. and Lawrence, D. and Navani, N. and Janes, S.M. and Dive, C. and Blackhall, F.H and Summers, Y. and Cave, J. and Marafioti, T. and Herrero, J. and Quezada, S.A. and Peggs, K.S. and Schwarz, R.F. and Van Loo, P. and Miedema, D.M. and Birkbak, N.J. and Hiley, C.T. and Hackshaw, A. and Zaccaria, S. and Jamal-Hanjani, M. and McGranahan, N. and Swanton, C.
Nature 616 (7957): 525-533. 20 April 2023

The little skate genome and the evolutionary emergence of wing-like fins.
Marlétaz, F. and de la Calle-Mustienes, E. and Acemel, R.D. and Paliou, C. and Naranjo, S. and Martínez-García, P.M. and Cases, I. and Sleight, V.A. and Hirschberger, C. and Marcet-Houben, M. and Navon, D. and Andrescavage, A. and Skvortsova, K. and Duckett, P.Ed. and González-Rajal, Á. and Bogdanovic, O. and Gibcus, J.H. and Yang, L. and Gallardo-Fuentes, L. and Sospedra, I. and Lopez-Rios, J. and Darbellay, F. and Visel, A. and Dekker, J. and Shubin, N. and Gabaldón, T. and Nakamura, T. and Tena, J.J. and Lupianez, D.G. and Rokhsar, D.S. and Gómez-Skarmeta, J.L.
Nature 616 (7957): 495-503. 20 April 2023

Genomic–transcriptomic evolution in lung cancer and metastasis.
Martínez-Ruiz, C. and Black, J.R.M. and Puttick, C. and Hill, M.S. and Demeulemeester, J. and Larose Cadieux, E. and Thol, K. and Jones, T.P. and Veeriah, S. and Naceur-Lombardelli, C. and Toncheva, A. and Prymas, P. and Rowan, A. and Ward, S. and Cubitt, L. and Athanasopoulou, F. and Pich, O. and Karasaki, T. and Moore, D.A. and Salgado, R. and Colliver, E. and Castignani, C. and Dietzen, M. and Huebner, A. and Al Bakir, M. and Tanić, M. and Watkins, T.B.K. and Lim, E.L. and Al-Rashed, A.M. and Lang, D. and Clements, J. and Cook, D.E. and Rosenthal, R. and Wilson, G. A. and Frankell, A.M. and de Carné Trécesson, S. and East, P. and Kanu, N. and Litchfield, K. and Birkbak, N.J. and Hackshaw, A. and Beck, S. and Van Loo, P. and Jamal-Hanjani, M. and McGranahan, N. and Swanton, C.
Nature 616 (7957): 543-552. 20 April 2023

Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
Ng, K.W. and Boumelha, J. and Enfield, K.S.S. and Almagro, J. and Cha, H. and Pich, O. and Karasaki, T. and Moore, D.A. and Salgado, R. and Sivakumar, M. and Young, G. and Molina-Arcas, M. and de Carné Trécesson, S. and Anastasiou, P. and Fendler, A. and Au, L. and Shepherd, S.T.C. and Martínez-Ruiz, C. and Puttick, C. and Black, J.R.M. and Watkins, T.B.K. and Kim, H. and Shim, S. and Faulkner, N. and Attig, J. and Veeriah, S. and Magno, N. and Ward, S. and Frankell, A.M. and Al Bakir, M. and Lim, E.L. and Hill, M.S. and Wilson, G.A. and Cook, D.E. and Birkbak, N.J. and Behrens, A. and Yousaf, N. and Popat, S. and Hackshaw, A. and Hiley, C.T. and Litchfield, K. and McGranahan, N. and Jamal-Hanjani, M. and Larkin, J. and Lee, S.H. and Turajlic, S. and Swanton, C. and Downward, J. and Kassiotis, G.
Nature 616 (7957): 563-573. 20 April 2023

A hydraulic feedback loop between mesendoderm cell migration and interstitial fluid relocalization promotes embryonic axis formation in zebrafish.
Huljev, K. and Shamipour, S. and Pinheiro, D. and Preusser, F. and Steccari, I. and Sommer, C.M. and Naik, S. and Heisenberg, C.P.
Developmental Cell 58 (7): 582-596.e7. 10 April 2023

Lung adenocarcinoma promotion by air pollutants.
Hill, W. and Lim, E.L. and Weeden, C.E. and Lee, C. and Augustine, M. and Chen, K. and Kuan, F.C. and Marongiu, F. and Evans, E.J. and Moore, D.A. and Rodrigues, F.S. and Pich, O. and Bakker, B. and Cha, H. and Myers, R. and van Maldegem, F. and Boumelha, J. and Veeriah, S. and Rowan, A. and Naceur-Lombardelli, C. and Karasaki, T. and Sivakumar, M. and De, S. and Caswell, D.R. and Nagano, A. and Black, J.R.M. and Martínez-Ruiz, C. and Ryu, M.H. and Huff, R.D. and Li, S. and Favé, M.J. and Magness, A. and Suárez-Bonnet, A. and Priestnall, S.L. and Lüchtenborg, M. and Lavelle, K. and Pethick, J. and Hardy, S. and McRonald, F.E. and Lin, M.H. and Troccoli, C.I. and Ghosh, M. and Miller, Y.E. and Merrick, D.T. and Keith, R.L. and Al Bakir, M. and Bailey, C. and Hill, M.S. and Saal, L.H. and Chen, Y. and George, A.M. and Abbosh, C. and Kanu, N. and Lee, S.H. and McGranahan, N. and Berg, C.D. and Sasieni, P. and Houlston, R. and Turnbull, C. and Lam, S. and Awadalla, P. and Grönroos, E. and Downward, J. and Jacks, T. and Carlsten, C. and Malanchi, I. and Hackshaw, A. and Litchfield, K. and DeGregori, J. and Jamal-Hanjani, M. and Swanton, C.
Nature 616 (7955): 159-167. 6 April 2023

Role of TMEM100 in mechanically insensitive nociceptor un-silencing.
Nees, T.A. and Wang, N. and Adamek, P. and Zeitzschel, N. and Verkest, C. and La Porta, C. and Schaefer, I. and Virnich, J. and Balkaya, S. and Prato, V. and Morelli, C. and Begay, V. and Lee, Y.J. and Tappe-Theodor, A. and Lewin, G.R. and Heppenstall, P.A. and Taberner, F.J. and Lechner, S.G.
Nature Communications 14 (1): 1899. 5 April 2023

Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
Kapell, H. and Fazio, L. and Dyckow, J. and Schwarz, S. and Cruz-Herranz, A. and Campos, J. and Mayer, C. and D Este, E. and Möbius, W. and Cordano, C. and Pröbstel, A.K. and Gharagozloo, M. and Zulji, A. and Narayanan Naik, V. and Delank, A.K. and Cerina, M. and Müntefering, T. and Lerma-Martin, C. and Sonner, J.K. and Sin, J.H. and Disse, P. and Rychlik, N. and Sabeur, K. and Chavali, M. and Srivastava, R. and Heidenreich, M. and Fitzgerald, K.C. and Seebohm, G. and Stadelmann, C. and Hemmer, B. and Platten, M. and Jentsch, T.J. and Engelhardt, M. and Budde, T. and Nave, K.A. and Calabresi, P.A. and Friese, M.A. and Green, A.J. and Acuna, C. and Rowitch, D.H. and Meuth, S.G. and Schirmer, L.
Journal of Clinical Investigation 133 (7): e164223. 3 April 2023

Targeting B cells and microglia in multiple sclerosis with Bruton tyrosine kinase inhibitors: a review.
Dybowski, S. and Torke, S. and Weber, M.S.
JAMA Neurology 80 (4): 404-414. 1 April 2023

The evolution of non-small cell lung cancer metastases in TRACERx.
Al Bakir, M. and Huebner, A. and Martínez-Ruiz, C. and Grigoriadis, K. and Watkins, T.B.K. and Pich, O. and Moore, D.A. and Veeriah, S. and Ward, S. and Laycock, J. and Johnson, D. and Rowan, A. and Razaq, M. and Akther, M. and Naceur-Lombardelli, C. and Prymas, P. and Toncheva, A. and Hessey, S. and Dietzen, M. and Colliver, E. and Frankell, A.M. and Bunkum, A. and Lim, E.L. and Karasaki, T. and Abbosh, C. and Hiley, C.T. and Hill, M.S. and Cook, D.E. and Wilson, G.A. and Salgado, R. and Nye, E. and Stone, R.K. and Fennell, D.A. and Price, G. and Kerr, K.M. and Naidu, B. and Middleton, G. and Summers, Y. and Lindsay, C.R. and Blackhall, F.H. and Cave, J. and Blyth, K.G. and Nair, A. and Ahmed, A. and Taylor, M.N. and Procter, A.J. and Falzon, M. and Lawrence, D. and Navani, N. and Thakrar, R.M. and Janes, S.M. and Papadatos-Pastos, D. and Forster, M.D. and Lee, S.M. and Ahmad, T. and Quezada, S.A. and Peggs, K.S. and Van Loo, P. and Dive, C. and Hackshaw, A. and Birkbak, N.J. and Zaccaria, S. and Jamal-Hanjani, M. and McGranahan, N. and Swanton, C.
Nature 616 (7957): 534-542. April 2023

Body composition and lung cancer-associated cachexia in TRACERx.
Al-Sawaf, O. and Weiss, J. and Skrzypski, M. and Lam, J.M. and Karasaki, T. and Zambrana, F. and Kidd, A.C. and Frankell, A.M. and Watkins, T.B.K. and Martínez-Ruiz, C. and Puttick, C. and Black, J.R.M. and Huebner, A. and Bakir, M.A. and Sokač, M. and Collins, S. and Veeriah, S. and Magno, N. and Naceur-Lombardelli, C. and Prymas, P. and Toncheva, A. and Ward, S. and Jayanth, N. and Salgado, R. and Bridge, C.P. and Christiani, D.C. and Mak, R.H. and Bay, C. and Rosenthal, M. and Sattar, N. and Welsh, P. and Liu, Y. and Perrimon, N. and Popuri, K. and Beg, M.F. and McGranahan, N. and Hackshaw, A. and Breen, D.M. and O'Rahilly, S. and Birkbak, N.J. and Aerts, H.J.W.L. and Jamal-Hanjani, M. and Swanton, C.
Nature Medicine 29 (4): 846-858. April 2023

The effect of probiotic and synbiotic supplementation on lipid parameters among patients with cardiometabolic risk factors: a systematic review and meta-analysis of clinical trials.
Ghorbani, Z. and Kazemi, A. and Bartolomaeus, T.U.P. and Martami, F. and Noormohammadi, M. and Salari, A. and Löber, U. and Balou, H.A. and Forslund, S.K. and Mahdavi-Roshan, M.
Cardiovascular Research 119 (4): 933-956. April 2023

A consensus protocol for functional connectivity analysis in the rat brain.
Grandjean, J. and Desrosiers-Gregoire, G. and Anckaerts, C. and Angeles-Valdez, D. and Ayad, F. and Barrière, D.A. and Blockx, I. and Bortel, A. and Broadwater, M. and Cardoso, B.M. and Célestine, M. and Chavez-Negrete, J.E. and Choi, S. and Christiaen, E. and Clavijo, P. and Colon-Perez, L. and Cramer, S. and Daniele, T. and Dempsey, E. and Diao, Y. and Doelemeyer, A. and Dopfel, D. and Dvořáková, L. and Falfán-Melgoza, C. and Fernandes, F.F. and Fowler, C.F. and Fuentes-Ibañez, A. and Garin, C.M. and Gelderman, E. and Golden, C.E.M. and Guo, C.C G. and Henckens, M.J.A.G. and Hennessy, L.A. and Herman, P. and Hofwijks, N. and Horien, C. and Ionescu, T.M. and Jones, J. and Kaesser, J. and Kim, E. and Lambers, H. and Lazari, A. and Lee, S.H. and Lillywhite, A. and Liu, Y. and Liu, Y.Y. and López-Castro, A. and López-Gil, X. and Ma, Z. and MacNicol, E. and Madularu, D. and Mandino, F. and Marciano, S. and McAuslan, M.J. and McCunn, P. and McIntosh, A. and Meng, X. and Meyer-Baese, L. and Missault, S. and Moro, F. and Naessens, D.M.P. and Nava-Gomez, L.J. and Nonaka, H. and Ortiz, J.J. and Paasonen, J. and Peeters, L.M. and Pereira, M. and Perez, P.D. and Pompilus, M. and Prior, M. and Rakhmatullin, R. and Reimann, H.M. and Reinwald, J. and Del Rio, R.T. and Rivera-Olvera, A. and Ruiz-Pérez, D. and Russo, G. and Rutten, T.J. and Ryoke, R. and Sack, M. and Salvan, P. and Sanganahalli, B.G. and Schroeter, A. and Seewoo, B.J. and Selingue, E. and Seuwen, A. and Shi, B. and Sirmpilatze, N. and Smith, J.A.B. and Smith, C. and Sobczak, F. and Stenroos, P.J. and Straathof, M. and Strobelt, S. and Sumiyoshi, A. and Takahashi, K. and Torres-García, M.E and Tudela, R. and van den Berg, M. and van der Marel, K. and van Hout, A.T.B. and Vertullo, R. and Vidal, B. and Vrooman, R.M. and Wang, V.X. and Wank, I. and Watson, D.J.G. and Yin, T. and Zhang, Y. and Zurbruegg, S. and Achard, S. and Alcauter, S. and Auer, D.P. and Barbier, E.L. and Baudewig, J. and Beckmann, C.F. and Beckmann, N. and Becq, G.J.P.C. and Blezer, E.L.A. and Bolbos, R. and Boretius, S. and Bouvard, S. and Budinger, E. and Buxbaum, J.D. and Cash, D. and Chapman, V. and Chuang, K.H. and Ciobanu, L. and Coolen, B.F. and Dalley, J.W. and Dhenain, M. and Dijkhuizen, R.M. and Esteban, O. and Faber, C. and Febo, M. and Feindel, K.W. and Forloni, G. and Fouquet, J. and Garza-Villarreal, E.A. and Gass, N. and Glennon, J.C. and Gozzi, A. and Gröhn, O. and Harkin, A. and Heerschap, A. and Helluy, X. and Herfert, K. and Heuser, A. and Homberg, J.R. and Houwing, D.J. and Hyder, F. and Ielacqua, G.D. and Jelescu, I.O. and Johansen-Berg, H. and Kaneko, G. and Kawashima, R. and Keilholz, S.D. and Keliris, G.A. and Kelly, C. and Kerskens, C. and Khokhar, J.Y. and Kind, P.C. and Langlois, J.B. and Lerch, J.P. and López-Hidalgo, M.A and Manahan-Vaughan, D. and Marchand, F. and Mars, R.B. and Marsella, G. and Micotti, E. and Muñoz-Moreno, E. and Near, J. and Niendorf, T. and Otte, W.M. and Pais-Roldán, P. and Pan, W.J. and Prado-Alcalá, R.A. and Quirarte, G.L. and Rodger, J. and Rosenow, T. and Sampaio-Baptista, C. and Sartorius, A. and Sawiak, S.J. and Scheenen, T.W.J. and Shemesh, N. and Shih, Y.Y.I. and Shmuel, A. and Soria, G. and Stoop, R. and Thompson, G.J. and Till, S.M. and Todd, N. and Van Der Linden, A. and van der Toorn, A. and van Tilborg, G.A.F and Vanhove, C. and Veltien, A. and Verhoye, M. and Wachsmuth, L. and Weber-Fahr, W. and Wenk, P. and Yu, X. and Zerbi, V. and Zhang, N. and Zhang, B.B. and Zimmer, L. and Devenyi, G.A. and Chakravarty, M.M. and Hess, A.
Nature Neuroscience 26 (4): 673-681. April 2023

Evolutionary characterization of lung adenocarcinoma morphology in TRACERx.
Karasaki, T. and Moore, D.A. and Veeriah, S. and Naceur-Lombardelli, C. and Toncheva, A. and Magno, N. and Ward, S. and Bakir, M.A. and Watkins, T.B.K. and Grigoriadis, K. and Huebner, A. and Hill, M.S. and Frankell, A.M. and Abbosh, C. and Puttick, C. and Zhai, H. and Gimeno-Valiente, F. and Saghafinia, S. and Kanu, N. and Dietzen, M. and Pich, O. and Lim, E.. and Martínez-Ruiz, C. and Black, J.R.M. and Biswas, D. and Campbell, B.B. and Lee, C. and Colliver, E. and Enfield, K.S.S. and Hessey, S. and Hiley, C.T. and Zaccaria, S. and Litchfield, K. and Birkbak, N.J. and Cadieux, E.L. and Demeulemeester, J. and Van Loo, P. and Adusumilli, P.S. and Tan, K.S. and Cheema, W. and Sanchez-Vega, F. and Jones, D.R. and Rekhtman, N. and Travis, W.D. and Hackshaw, A. and Marafioti, T. and Salgado, R. and Le Quesne, J. and Nicholson, A.G. and McGranahan, N. and Swanton, C. and Jamal-Hanjani, M.
Nature Medicine 29 (4): 833-845. April 2023

The genomic landscape across 474 surgically accessible epileptogenic human brain lesions.
López-Rivera, J.A. and Leu, C. and Macnee, M. and Khoury, J. and Hoffmann, L. and Coras, R. and Kobow, K. and Bhattarai, N. and Pérez-Palma, E. and Hamer, H. and Brandner, S. and Rössler, K. and Bien, C.G. and Kalbhenn, T. and Pieper, T. and Hartlieb, T. and Butler, E. and Genovese, G. and Becker, K. and Altmüller, J. and Niestroj, L.M. and Ferguson, L. and Busch, R.M. and Nürnberg, P. and Najm, I. and Blümcke, I. and Lal, D.
Brain 146 (4): 1342-1356. April 2023

COVID-19 and cellular senescence.
Schmitt, C.A. and Tchkonia, T. and Niedernhofer, L.J. and Robbins, P.D. and Kirkland, J.L. and Lee, S.
Nature Reviews Immunology 23 (4): 251-263. April 2023

Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Straube, J. and Eifert, T. and Vu, T. and Janardhanan, Y. and Haldar, R. and von Eyss, B. and Cooper, L. and Bruedigam, C. and Ling, V.Y. and Cooper, E. and Patch, A.M. and Bullinger, L. and Schnoeder, T.M. and Bywater, M. and Heidel, F.H. and Lane, S.W.
Leukemia 37 (4): 741-750. April 2023

Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Weigert, R. and Hetzel, S. and Bailly, N. and Haggerty, C. and Ilik, I.A. and Yung, P.Y.K. and Navarro, C. and Bolondi, A. and Kumar, A.S. and Anania, C. and Brändl, B. and Meierhofer, D. and Lupianez, D.G. and Müller, F.J. and Aktas, T. and Elsässer, S.J. and Kretzmer, H. and Smith, Z.D. and Meissner, A.
Nature Cell Biology 25 : 579–591. April 2023

Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root.
Nolan, T.M. and Vukašinović, N. and Hsu, C.W. and Zhang, J. and Vanhoutte, I. and Shahan, R. and Taylor, I.W. and Greenstreet, L. and Heitz, M. and Afanassiev, A. and Wang, P. and Szekely, P. and Brosnan, A. and Yin, Y. and Schiebinger, G. and Ohler, U. and Russinova, E. and Benfey, P.N.
Science 379 (6639): eadf4721. 31 March 2023

Integrated proteomics unveils nuclear PDE3A2 as a regulator of cardiac myocyte hypertrophy.
Subramaniam, G. and Schleicher, K. and Kovanich, D. and Zerio, A. and Folkmanaite, M. and Chao, Y.C. and Surdo, N.C. and Koschinski, A. and Hu, J. and Scholten, A. and Heck, A.J.R and Ercu, M. and Sholokh, A. and Chan Park, K. and Klussmann, E. and Meraviglia, V. and Bellin, M. and Zanivan, S. and Hester, S. and Mohammed, S. and Zaccolo, M.
Circulation Research 132 (7): 828-848. 31 March 2023

Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development.
Mueller-Calleja, N. and Grunz, K. and Nguyen, T.S. and Posma, J. and Pedrosa, D. and Meineck, M. and Hollerbach, A. and Braun, J. and Muth, S. and Schild, H. and Saar, K. and Hübner, N. and Krishnaswamy, S. and Royce, J. and Teyton, L. and Lemmermann, N.A. and Weinmann-Menke, J. and Lackner, K.J. and Ruf, W.
Blood 143 (12): 1167-1180. 21 March 2023

Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications.
Malinovska, L. and Cappelletti, V. and Kohler, D. and Piazza, I. and Tsai, T.H. and Pepelnjak, M. and Stalder, P. and Dörig, C. and Sesterhenn, F. and Elsässer, F. and Kralickova, L. and Beaton, N. and Reiter, L. and de Souza, N. and Vitek, O. and Picotti, P.
Nature Protocols 18 : 659-682. 16 March 2023

Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.
Sandmann, C.L. and Schulz, J.F. and Ruiz-Orera, J. and Kirchner, M. and Ziehm, M. and Adami, E. and Marczenke, M. and Christ, A. and Liebe, N. and Greiner, J. and Schoenenberger, A. and Mücke, M.B. and Liang, N. and Moritz, R.L. and Sun, Z. and Deutsch, E.W. and Gotthardt, M. and Mudge, J.M. and Prensner, J.R. and Willnow, T.E. and Mertins, P. and van Heesch, S. and Hubner, N.
Molecular Cell 83 (6): 994-1011.e18. 16 March 2023

Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Richter, F.C. and Friedrich, M. and Kampschulte, N. and Piletic, K. and Alsaleh, G. and Zummach, R. and Hecker, J. and Pohin, M. and Ilott, N. and Guschina, I. and Wideman, S.K. and Johnson, E. and Borsa, M. and Hahn, P. and Morriseau, C. and Hammock, B.D. and Schipper, H.S. and Edwards, C.M and Zechner, R. and Siegmund, B. and Weidinger, C. and Schebb, N.H. and Powrie, F. and Simon, A.K.
EMBO Journal 42 (6): e112202. 15 March 2023

Curvature in biological systems: its quantification, emergence and implications across the scales.
Schamberger, B. and Roschger, A. and Ziege, R. and Anselme, K. and Amar, M.B. and Bykowski, M. and Castro, A.P.G. and Cipitria, A. and Coles, R. and Dimova, R. and Eder, M. and Ehrig, S. and Escudero, L.M. and Evans, M.E. and Fernandes, P.R. and Fratzl, P. and Geris, L. and Gierlinger, N. and Hannezo, E. and Iglič, A. and Kirkensgaard, J.J.K. and Kollmannsberger, P. and Kowalewska, Ł. and Kurniawan, N.A. and Papantoniou, I. and Pieuchot, L. and Pires, T.H.V. and Renner, L. and Sageman-Furnas, A. and Schröder-Turk, G.E. and Sengupta, A. and Sharma, V.R. and Tagua, A. and Tomba, C. and Trepat, X. and Waters, S.L. and Yeo, E. and Bidan, C.M. and Dunlop, J.W.C.
Advanced Materials 35 (13): e2206110. 15 March 2023

Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda et al.
Immisch, L. and Papafotiou, G. and Popp, O. and Mertins, P. and Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 11 (3): e006784. 14 March 2023

Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy.
Kalkan, H. and Pagano, E. and Paris, D. and Panza, E. and Cuozzo, M. and Moriello, C. and Piscitelli, F. and Abolghasemi, A. and Gazzerro, E. and Silvestri, C. and Capasso, R. and Motta, A. and Russo, R. and Di Marzo, V. and Iannotti, F.A.
EMBO Molecular Medicine 15 (3): e16225. 8 March 2023

Mouse models of human multiple myeloma subgroups.
Winkler, W. and Farré Díaz, C. and Blanc, E. and Napieczynska, H. and Langner, P. and Werner, M. and Walter, B. and Wollert-Wulf, B. and Yasuda, T. and Heuser, A. and Beule, D. and Mathas, S. and Anagnostopoulos, I. and Rosenwald, A. and Rajewsky, K. and Janz, M.
Proceedings of the National Academy of Sciences of the United States of America 120 (10): e2219439120. 7 March 2023

The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Meier, M. and Gupta, M. and Akgül, S. and McDougall, M. and Imhof, T. and Nikodemus, D. and Reuten, R. and Moya-Torres, A. and To, V. and Ferens, F. and Heide, F. and Padilla-Meier, G.P. and Kukura, P. and Huang, W. and Gerisch, B. and Mörgelin, M. and Poole, K. and Antebi, A. and Koch, M. and Stetefeld, J.
Nature Communications 14 (1): 1226. 3 March 2023

Mitochondrial DNA mutations as natural barcodes for lineage tracing of murine tumor models.
Penter, L. and Ten Hacken, E. and Southard, J. and Lareau, C. and Ludwig, L.S. and Li, S. and Neuberg, D.S. and Livak, K.J. and Wu, C.J.
Cancer Research 83 (5): 667-672. 1 March 2023

First demonstration of miRNA-dependent mRNA decay.
Chekulaeva, M.
Nature Reviews Molecular Cell Biology 24 (3): 164. March 2023

CAR links hypoxia signaling to improved survival after myocardial infarction.
Freiberg, F. and Thakkar, M. and Hamann, W. and Lopez Carballo, J. and Jüttner, R. and Voss, F.K. and Becher, P.M. and Westermann, D. and Tschöpe, C. and Heuser, A. and Rocks, O. and Fischer, R. and Gotthardt, M.
Experimental and Molecular Medicine 55 (3): 643-652. March 2023

HNF1B alters an evolutionarily conserved nephrogenic program of target genes.
Grand, K. and Stoltz, M. and Rizzo, L. and Röck, R. and Kaminski, M.M. and Salinas, G. and Getwan, M. and Naert, T. and Pichler, R. and Lienkamp, S.S.
Journal of the American Society of Nephrology 34 (3): 412-432. March 2023

IFNγ binding to extracellular matrix prevents fatal systemic toxicity.
Kemna, J. and Gout, E. and Daniau, L. and Lao, J. and Weißert, K. and Ammann, S. and Kühn, R. and Richter, M. and Molenda, C. and Sporbert, A. and Zocholl, D. and Klopfleisch, R. and Schütz, A. and Lortat-Jacob, H. and Aichele, P. and Kammertoens, T. and Blankenstein, T.
Nature Immunology 24 (3): 414-422. March 2023

Aquaporin-2 is not alone.
Klussmann, E.
Kidney International 103 (3): 458-460. March 2023

Massively parallel identification of mRNA localization elements in primary cortical neurons.
Mendonsa, S. and von Kügelgen, N. and Dantsuji, S. and Ron, M. and Breimann, L. and Baranovskii, A. and Lödige, I. and Kirchner, M. and Fischer, M. and Zerna, N. and Bujanic, L. and Mertins, P. and Ulitsky, I. and Chekulaeva, M.
Nature Neuroscience 26 (3): 394-405. March 2023

The cellular coding of temperature in the mammalian cortex.
Vestergaard, M. and Carta, M. and Güney, G. and Poulet, J.F.A.
Nature 614 (7949): 725-731. 23 February 2023

Nivolumab and doxorubicin, vinblastine, and dacarbazine in early-stage unfavorable Hodgkin Lymphoma: final analysis of the randomized german Hodgkin study group phase II NIVAHL trial.
Bröckelmann, P.J. and Bühnen, I. and Meissner, J. and Trautmann-Grill, K. and Herhaus, P. and Halbsguth, T.V. and Schaub, V. and Kerkhoff, A. and Mathas, S. and Bormann, M. and Dickhut, A. and Kaul, H. and Fuchs, M. and Kobe, C. and Baues, C. and Borchmann, P. and Engert, A. and von Tresckow, B.
Journal of Clinical Oncology 41 (6): 1193-1199. 20 February 2023

Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.
Li, B. and Zeis, P. and Zhang, Y. and Alekseenko, A. and Fürst, E. and Sanchez, Y.P. and Lin, G. and Tekkedil, M.M. and Piazza, I. and Steinmetz, L.M. and Pelechano, V.
Nature Communications 14 (1): 910. 17 February 2023

Cryo-EM captures early ribosome assembly in action.
Qin, B. and Lauer, S.M. and Balke, A. and Vieira-Vieira, C.H. and Bürger, J. and Mielke, T. and Selbach, M. and Scheerer, P. and Spahn, C.M.T. and Nikolay, R.
Nature Communications 14 (1): 898. 17 February 2023

Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M. and Liman, T.G. and Strzelecka, P.M. and Kufner, A. and Löwe, P. and Huo, S. and Stein, C.M. and Piper, S.K. and Tilgner, M. and Sperber, P.S. and Dimitriou, S. and Heuschmann, P. and Hablesreiter, R. and Harms, C. and Bullinger, L. and Weber, J.E. and Endres, M. and Damm, F.
Blood 141 (7): 787-799. 16 February 2023

Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19.
Mothes, R. and Pascual-Reguant, A. and Koehler, R. and Liebeskind, J. and Liebheit, A. and Bauherr, S. and Philipsen, L. and Dittmayer, C. and Laue, M. and von Manitius, R. and Elezkurtaj, S. and Durek, P. and Heinrich, F. and Heinz, G.A. and Guerra, G.M. and Obermayer, B. and Meinhardt, J. and Ihlow, J. and Radke, J. and Heppner, F.L. and Enghard, P. and Stockmann, H. and Aschman, T. and Schneider, J. and Corman, V.M. and Sander, L.E. and Mashreghi, M.F. and Conrad, T. and Hocke, A.C. and Niesner, R.A. and Radbruch, H. and Hauser, A.E.
Nature Communications 14 (1): 791. 11 February 2023

Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Danielli, S.G. and Porpiglia, E. and De Micheli, A.J. and Navarro, N. and Zellinger, M.J. and Bechtold, I. and Kisele, S. and Volken, L. and Marques, J.G. and Kasper, S. and Bode, P.K. and Henssen, A.G. and Gürgen, D. and Delattre, O. and Surdez, D. and Roma, J. and Bühlmann, P. and Blau, H.M. and Wachtel, M. and Schäfer, B.W.
Science Advances 9 (6): eade9238. 10 February 2023

The brain's encoding of warm and cool.
Vestergaard, M. and Poulet, J.
Nature 8 February 2023 (In Press)

Cardiometabolic HFpEF: NASH of the heart.
Capone, F. and Vettor, Roberto and Schiattarella, G.G.
Circulation 147 (6): 451-453. 7 February 2023

Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.
Côrte-Real, B.F. and Hamad, I. and Arroyo Hornero, R. and Geisberger, S. and Roels, J. and Van Zeebroeck, L. and Dyczko, A. and van Gisbergen, M.W. and Kurniawan, H. and Wagner, A. and Yosef, N. and Weiss, S.N.Y. and Schmetterer, K.G. and Schröder, A. and Krampert, L. and Haase, S. and Bartolomaeus, H. and Hellings, N. and Saeys, Y. and Dubois, L.J. and Brenner, D. and Kempa, S. and Hafler, D.A. and Stegbauer, J. and Linker, R.A. and Jantsch, J. and Müller, D.N. and Kleinewietfeld, M.
Cell Metabolism 35 (2): 299-315. 7 February 2023

First in vivo fluorine-19 magnetic resonance imaging of the multiple sclerosis drug siponimod.
Starke, L. and Millward, J.M. and Prinz, C. and Sherazi, F. and Waiczies, H. and Lippert, C. and Nazaré, M. and Paul, F. and Niendorf, T. and Waiczies, S.
Theranostics 13 (4): 1217-1234. 5 February 2023

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas.
Lopez, C. and Schleussner, N. and Bernhart, S.H. and Kleinheinz, K. and Sungalee, S. and Sczakiel, H.L. and Kretzmer, H. and Toprak, U.H. and Glaser, S. and Wagener, R. and Ammerpohl, O. and Bens, S. and Giefing, M. and Sanchez, J.C.G. and Apic, G. and Hubschmann, D. and Janz, M. and Kreuz, M. and Mottok, A. and Müller, J.M. and Seufert, J. and Hoffmann, S. and Korbel, J.O. and Russell, R.B. and Schule, R. and Trumper, L. and Klapper, W. and Radlwimmer, B. and Lichter, P. and Kuppers, R. and Schlesner, M. and Mathas, S. and Siebert, R.
Haematologica 108 (2): 543-554. 1 February 2023

SLC26A1 is a major determinant of sulfate homeostasis in humans.
Pfau, A. and López-Cayuqueo, K.I. and Scherer, N. and Wuttke, M. and Wernstedt, A. and González Fassrainer, D. and Smith, D.E. and van de Kamp, J.M. and Ziegeler, K. and Eckardt, K.U. and Luft, F.C. and Aronson, P.S. and Köttgen, A. and Jentsch, T.J. and Knauf, F.
Journal of Clinical Investigation 133 (3): e161849. 1 February 2023

Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy.
Boogerd, C.J. and Lacraz, G.P.A. and Vértesy, Á. and van Kampen, S.J. and Perini, I. and de Ruiter, H. and Versteeg, D. and Brodehl, A. and van der Kraak, P. and Giacca, M. and de Jonge, N. and Junker, J.P. and van Oudenaarden, A. and Vink, A. and van Rooij, E.
Cardiovascular Research 119 (2): 477-491. February 2023

Small molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy.
Demel, U.M. and Wirth, M. and Yousefian, S. and Zhang, L. and Isaakidis, K. and Dönig, J. and Böger, M. and Singh, N. and Köse, H. and Haas, S. and Müller, S. and Schick, M. and Keller, U.
Haematologica 108 (2): 555-567. February 2023

Diverse effects of obesity on antitumor immunity and immunotherapy.
Dyck, L. and Lynch, L.
Trends in Molecular Medicine 29 (2): 112-123. February 2023

Fasting intervention and its clinical effects on the human host and microbiome.
Forslund, S.K.
Journal of Internal Medicine 293 (2): 166-183. February 2023

Long COVID and the cardiovascular system - elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial & Pericardial Diseases.
Gyöngyösi, M. and Alcaide, P. and Asselbergs, F.W. and Brundel, B.J.J.M. and Camici, G.G. and da Costa Martins, P. and Ferdinandy, P. and Fontana, M. and Girao, H. and Gnecchi, M. and Gollmann-Tepeköylü, C. and Kleinbongard, P. and Krieg, T. and Madonna, R. and Paillard, M. and Pantazis, A. and Perrino, C. and Pesce, M. and Schiattarella, G.G. and Sluijter, J.P.G. and Steffens, S. and Tschöpe, C. and Van Linthout, S. and Davidson, S.M.
Cardiovascular Research 119 (2): 336-356. February 2023

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.
Mansouri, L. and Thorvaldsdottir, B. and Sutton, L.A. and Karakatsoulis, G. and Meggendorfer, M. and Parker, H. and Nadeu, F. and Brieghel, C. and Laidou, S. and Moia, R. and Rossi, D. and Catherwood, M. and Kotaskova, J. and Delgado, J. and Rodríguez-Vicente, A.E. and Benito, R. and Rigolin, G.M. and Bonfiglio, S. and Scarfo, L. and Mattsson, M. and Davis, Z. and Gogia, A. and Rani, L. and Baliakas, P. and Foroughi-Asl, H. and Jylhä, C. and Skaftason, A. and Rapado, I. and Miras, F. and Martinez-Lopez, J. and de la Serna, J. and Rivas, J.M.H. and Thornton, P. and Larráyoz, M.J. and Calasanz, M.J. and Fésüs, V. and Mátrai, Z. and Bödör, C. and Smedby, K.E. and Espinet, B. and Puiggros, A. and Gupta, R. and Bullinger, L. and Bosch, F. and Tazón-Vega, B. and Baran-Marszak, F. and Oscier, D. and Nguyen-Khac, F. and Zenz, T. and Terol, M.J. and Cuneo, A. and Hernández-Sánchez, M. and Pospisilova, S. and Mills, K. and Gaidano, G. and Niemann, C.U. and Campo, E. and Strefford, J.C. and Ghia, P. and Stamatopoulos, K. and Rosenquist, R.
Leukemia 37 (2): 339-347. February 2023

Generation of TGFβR2(-1) neoantigen-specific HLA-DR4-restricted T cell receptors for cancer therapy.
Plewa, N. and Poncette, L. and Blankenstein, T.
Journal for ImmunoTherapy of Cancer 11 (2): e006001. February 2023

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies.
Kennedy, K.M. and de Goffau, M.C. and Perez-Muñoz, M.E. and Arrieta, M.C. and Bäckhed, F. and Bork, P. and Braun, T. and Bushman, F.D. and Dore, J. and de Vos, W.M. and Earl, A.M. and Eisen, J.A. and Elovitz, M.A. and Ganal-Vonarburg, S.C. and Gänzle, M.G. and Garrett, W.S. and Hall, L.J. and Hornef, M.W. and Huttenhower, C. and Konnikova, L. and Lebeer, S. and Macpherson, A.J. and Massey, R.C. and McHardy, A.C. and Koren, O. and Lawley, T.D. and Ley, R.E. and O'Mahony, L. and O'Toole, P.W. and Pamer, E.G. and Parkhill, J. and Raes, J. and Rattei, T. and Salonen, A. and Segal, E. and Segata, N. and Shanahan, F. and Sloboda, D.M. and Smith, G.C.S. and Sokol, H. and Spector, T.D. and Surette, M.G. and Tannock, G.W. and Walker, A.W. and Yassour, M. and Walter, J.
Nature 613 (7945): 639-649. 26 January 2023

CYCLeR - a novel tool for the full isoform assembly and quantification of circRNAs.
Stefanov, S.R. and Meyer, I.M.
Nucleic Acids Research 51 (2): e10. 25 January 2023

Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Petrović, S. and Roske, Y. and Rami, B. and Phan, M.H.Q. and Panakova, D. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 120 (4): e2208941120. 24 January 2023

Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging.
Espiritu, J. and Berangi, M. and Cwieka, H. and Iskhakova, K. and Kuehne, A. and Florian Wieland, D.C. and Zeller-Plumhoff, B. and Niendorf, T. and Willumeit-Römer, R. and Seitz, J.M.
Bioactive Materials 25 : 86-94. 23 January 2023

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M. and Franke, V. and Benedum, J. and Grishkovskaya, I. and Strobl, X. and Polyansky, A. and Ammann, G. and Platzer, S. and Neudolt, A. and Wunder, A. and Walch, L. and Kaiser, S. and Zagrovic, B. and Djinovic-Carugo, K. and Akalin, A. and Slade, D.
Nature Communications 14 (1): 166. 11 January 2023

proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes.
Fullam, A. and Letunic, I. and Schmidt, T.S.B. and Ducarmon, Q.R. and Karcher, N. and Khedkar, S. and Kuhn, M. and Larralde, M. and Maistrenko, O.M. and Malfertheiner, L. and Milanese, A. and Rodrigues, J.F.M. and Sanchis-López, C. and Schudoma, C. and Szklarczyk, D. and Sunagawa, S. and Zeller, G. and Huerta-Cepas, J. and von Mering, C. and Bork, P. and Mende, D.R.
Nucleic Acids Research 51 (D1): D760-D766. 6 January 2023

The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest.
Szklarczyk, D. and Kirsch, R. and Koutrouli, M. and Nastou, K. and Mehryary, F. and Hachilif, R. and Gable, A.L. and Fang, T. and Doncheva, N.T. and Pyysalo, S. and Bork, P. and Jensen, L.J. and von Mering, C.
Nucleic Acids Research 51 (D1): D638-D646. 6 January 2023

The gut microbiota in multiple sclerosis varies with disease activity.
Thirion, F. and Sellebjerg, F. and Fan, Y. and Lyu, L. and Hansen, T.H. and Pons, N. and Levenez, F. and Quinquis, B. and Stankevic, E. and Søndergaard, H.B. and Dantoft, T.M. and Poulsen, C.S. and Forslund, S.K. and Vestergaard, H. and Hansen, T. and Brix, S. and Oturai, A. and Sørensen, P.S. and Ehrlich, S.D. and Pedersen, O.
Genome Medicine 15 (1): 1. 5 January 2023

A guide to naming eukaryotic circular RNAs.
Chen, L.L. and Bindereif, A. and Bozzoni, I. and Chang, H.Y. and Matera, A.G. and Gorospe, M. and Hansen, T.B. and Kjems, J. and Ma, X.K. and Pek, J.W. and Rajewsky, N. and Salzman, J. and Wilusz, J.E. and Yang, L. and Zhao, F.
Nature Cell Biology 25 (1): 1-5. January 2023

Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.
Denkinger, C.M. and Janssen, M. and Schäkel, U. and Gall, J. and Leo, A. and Stelmach, P. and Weber, S.F. and Krisam, J. and Baumann, L. and Stermann, J. and Merle, U. and Weigand, M.A. and Nusshag, C. and Bullinger, L. and Schrezenmeier, J.F. and Bornhäuser, M. and Alakel, N. and Witzke, O. and Wolf, T. and Vehreschild, M.J.G.T. and Schmiedel, S. and Addo, M.M. and Herth, F. and Kreuter, M. and Tepasse, P.R. and Hertenstein, B. and Hänel, M. and Morgner, A. and Kiehl, M. and Hopfer, O. and Wattad, M.A. and Schimanski, C.C. and Celik, C. and Pohle, T. and Ruhe, M. and Kern, W.V. and Schmitt, A. and Lorenz, H.M. and Souto-Carneiro, M. and Gaeddert, M. and Halama, N. and Meuer, S. and Kräusslich, H.G. and Müller, B. and Schnitzler, P. and Parthé, S. and Bartenschlager, R. and Gronkowski, M. and Klemmer, J. and Schmitt, M. and Dreger, P. and Kriegsmann, K. and Schlenk, Ri.F. and Müller-Tidow, C.
Nature Cancer 4 (1): 96-107. January 2023

A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O. and Jia, A. and Kuehn, H.S. and Min, Q. and Pannicke, U. and Schleussner, N. and Thouenon, R. and Yu, Z. and de Los Angeles Astbury, M. and Biggs, C.M. and Galicchio, M. and Garcia-Campos, J.A. and Gismondi, S. and Gonzalez Villarreal, G. and Hildebrand, K.J. and Hönig, M. and Hou, J. and Moshous, D. and Pittaluga, S. and Qian, X. and Rozmus, J. and Schulz, A.S. and Staines-Boone, A.T. and Sun, B. and Sun, J. and Uwe, S. and Venegas-Montoya, E. and Wang, W. and Wang, X. and Ying, W. and Zhai, X. and Zhou, Q. and Akalin, A. and André, I. and Barth, T.F.E. and Baumann, B. and Brüstle, A. and Burgio, G. and Bustamante, J.C. and Casanova, J.L. and Casarotto, M.G. and Cavazzana, M. and Chentout, L. and Cockburn, I.A. and Costanza, M. and Cui, C. and Daumke, O. and Del Bel, K.L. and Eibel, H. and Feng, X. and Franke, V. and Gebhardt, J.C.M. and Götz, A. and Grunwald, S. and Hoareau, B. and Hughes, T.R. and Jacobsen, E.M. and Janz, M. and Jolma, A. and Lagresle-Peyrou, C. and Lai, N. and Li, Y. and Lin, S. and Lu, H.Y. and Lugo-Reyes, S.O. and Meng, X. and Möller, P. and Moreno-Corona, N. and Niemela, J.E. and Novakovsky, G. and Perez-Caraballo, J.J. and Picard, C. and Poggi, L. and Puig-Lombardi, M.E. and Randall, K.L. and Reisser, A. and Schmitt, Y. and Seneviratne, S. and Sharma, M. and Stoddard, J. and Sundararaj, S. and Sutton, H. and Tran, L.Q. and Wang, Y. and Wasserman, W.W. and Wen, Z. and Winkler, W. and Xiong, E. and Yang, A.W.H. and Yu, M. and Zhang, L. and Zhang, H. and Zhao, Q. and Zhen, X. and Enders, A. and Kracker, S. and Martinez-Barricarte, R. and Mathas, S. and Rosenzweig, S.D. and Schwarz, K. and Turvey, S.E. and Wang, J.Y.
Science Immunology 8 (79): eade7953. January 2023

Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B cell impairment and increases the risk for infections - a retrospective matched cohort study.
Launspach, M. and Temel, D. and Ohlendorf, E. and Zirngibl, F. and Materne, B. and Oevermann, L. and Deubzer, H.E. and Henssen, A.G. and Künkele, A. and Hundsdörfer, P. and von Bernuth, H. and Pruß, A. and Eggert, A. and von Stackelberg, A. and Lang, P. and Schulte, J.H.
Haematologica 108 (1): 267-272. January 2023

Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia.
Ling, V.Y. and Straube, J. and Godfrey, W. and Haldar, R. and Janardhanan, Y. and Cooper, L. and Bruedigam, C. and Cooper, E. and Tavakoli Shirazi, P. and Jacquelin, S. and Tey, S.K. and Baell, J. and Huang, F. and Jin, J. and Zhao, Y. and Bullinger, L. and Bywater, M.J. and Lane, S.W.
Leukemia 37 (1): 143-153. January 2023

Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
Lo, W.T. and Belabed, H. and Kücükdisli, M. and Metag, J. and Roske, Y. and Prokofeva, P. and Ohashi, Y. and Horatscheck, A. and Cirillo, D. and Krauss, M. and Schmied, C. and Neuenschwander, M. and von Kries, J.P. and Médard, G. and Kuster, Be. and Perisic, O. and Williams, R.L. and Daumke, O. and Payrastre, B. and Severin, S. and Nazaré, M. and Haucke, V.
Nature Chemical Biology 19 (1): 18-27. January 2023

Automated reconstruction of whole-embryo cell lineages by learning from sparse annotations.
Malin-Mayor, C. and Hirsch, P. and Guignard, L. and McDole, K. and Wan, Y. and Lemon, W.C. and Kainmueller, D. and Keller, P.J. and Preibisch, S. and Funke, J.
Nature Biotechnology 44 (1): 44-49. January 2023

2022

Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Keil, P. and Wulf, A. and Kachariya, N. and Reuscher, S. and Hühn, K. and Silbern, I. and Altmüller, J. and Keller, M. and Stehle, R. and Zarnack, K. and Sattler, M. and Urlaub, H. and Sträßer, K.
Nucleic Acids Research : gkac1206. 30 December 2022

Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses.
Kunath, B.J. and Hickl, O. and Queirós, P. and Martin-Gallausiaux, C. and Lebrun, L.A. and Halder, R. and Laczny, C.C. and Schmidt, T.S.B. and Hayward, M.R. and Becher, D. and Heintz-Buschart, A. and de Beaufort, C. and Bork, P. and May, P. and Wilmes, P.
Microbiome 10 (1): 243. 28 December 2022

TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck, F. and Fischer, B. and Witt, M. and Muschhammer, J. and Oelrich, J. and da Costa Avelar, P.H. and Tsoka, S. and Bullinger, L. and Seubert, E. and Smit, D.J. and Bokemeyer, C. and Ackermann, C. and Wellbrock, J. and Haag, F. and Fiedler, W.
Journal for ImmunoTherapy of Cancer 10 (12): e004794. 22 December 2022

Calcium-permeable channelrhodopsins for the photocontrol of calcium signalling.
Fernandez Lahore, R.G. and Pampaloni, N.P. and Schiewer, E. and Heim, M.M. and Tillert, L. and Vierock, J. and Oppermann, J. and Walther, J. and Schmitz, D. and Owald, D. and Plested, A.J.R. and Rost, B.R. and Hegemann, P.
Nature Communications 13 (1): 7844. 21 December 2022

Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its host.
Midha, A. and Jarquín-Díaz, V.H. and Ebner, F. and Löber, U. and Hayani, R. and Kundik, A. and Cardilli, A. and Heitlinger, E. and Forslund, S.K. and Hartmann, S.
Microbiome 10 (1): 229. 16 December 2022

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A. and Sprink, T. and Noel, J.K. and Vázquez-Sarandeses, E. and van Hoorn, C. and Mohd, S. and Loerke, J. and Spahn, C.M.T. and Daumke, O.
Nature Communications 13 (1): 7641. 10 December 2022

Robust induction of primordial germ cells of white rhinoceros on the brink of extinction.
Hayashi, M. and Zywitza, V. and Naitou, Y. and Hamazaki, N. and Goeritz, F. and Hermes, R. and Holtze, S. and Lazzari, G. and Galli, C. and Stejskal, J. and Diecke, S. and Hildebrandt, T.B. and Hayashi, K.
Science Advances 8 (49): eabp9683. 9 December 2022

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M. and Mücke, M.B. and Pallien, T. and Markó, L. and Sholokh, A. and Schächterle, C. and Aydin, A. and Kidd, A. and Walter, S. and Esmati, Y. and McMurray, B.J. and Lato, D.F. and Sunaga-Franze, D.Y. and Dierks, P.H. and Flores, B.I.M. and Walker-Gray, R. and Gong, M. and Merticariu, C. and Zühlke, K. and Russwurm, M. and Liu, T. and Batolomaeus, T.U.P. and Pautz, S. and Schelenz, S. and Taube, M. and Napieczynska, H. and Heuser, A. and Eichhorst, J. and Lehmann, M. and Miller, D.C. and Diecke, S. and Qadri, F. and Popova, E. and Langanki, R. and Movsesian, M.A. and Herberg, F.W. and Forslund, S.K. and Müller, D.N. and Borodina, T. and Maass, P.G. and Bähring, S. and Hübner, N. and Bader, M. and Klussmann, E.
Circulation 146 (23): 1758-1778. 6 December 2022

Cultivation-independent genomes greatly expand taxonomic-profiling capabilities of mOTUs across various environments.
Ruscheweyh, H.J. and Milanese, A. and Paoli, L. and Karcher, N. and Clayssen, Q. and Keller, M.I. and Wirbel, J. and Bork, P. and Mende, D.R. and Zeller, G. and Sunagawa, S.
Microbiome 10 (1): 212. 5 December 2022

Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.
Widjaja, A.A. and Viswanathan, S. and Shekeran, S.G. and Adami, E. and Lim, W.W. and Chothani, S. and Tan, J. and Goh, J.W.T. and Chen, H.M. and Lim, S.Y. and Boustany-Kari, C.M. and Hawkins, J. and Petretto, E. and Hübner, N. and Schafer, S. and Coffman, T.M. and Cook, S.A.
Nature Communications 13 (1): 7497. 5 December 2022

Endothelin antagonists and the quest for a new therapeutic option in resistant hypertension.
Dechend, R. and Delles, C.
Lancet 400 (10367): 1900-1901. 3 December 2022

Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
Ebert, M.J. and Jerke, U. and Eulenberg-Gustavus, C. and Kling, L. and Jenne, D.E. and Kirchner, M. and Mertins, P. and Bieringer, M. and Elitok, S. and Eckardt, K.U. and Schreiber, A. and Salama, A.D. and Kettritz, R.
Journal of Clinical Investigation 132 (23): e160089. 1 December 2022

Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke, K. and Obermayer, B. and Mache, C. and Fathykova, D. and Kessler, M. and Dökel, S. and Wyler, E. and Baumgardt, M. and Löwa, A. and Hoffmann, K. and Graff, P. and Schulze, J. and Mieth, M. and Hellwig, K. and Demir, Z. and Biere, B. and Brunotte, L. and Mecate-Zambrano, A. and Bushe, J. and Dohmen, M. and Hinze, C. and Elezkurtaj, S. and Tönnies, M. and Bauer, T.T. and Eggeling, S. and Tran, H.L. and Schneider, P. and Neudecker, J. and Rückert, J.C. and Schmidt-Ott, K.M. and Busch, J. and Klauschen, F. and Horst, D. and Radbruch, H. and Radke, J. and Heppner, F. and Corman, V.M. and Niemeyer, D. and Müller, M.A. and Goffinet, C. and Mothes, R. and Pascual-Reguant, A. and Hauser, A.E. and Beule, D. and Landthaler, M. and Ludwig, S. and Suttorp, N. and Witzenrath, M. and Gruber, A.D. and Drosten, C. and Sander, L.E. and Wolff, T. and Hippenstiel, S. and Hocke, A.C.
European Respiratory Journal 60 (6): 2102725. 1 December 2022

RS-FISH: precise, interactive, fast, and scalable FISH spot detection.
Bahry, E. and Breimann, L. and Zouinkhi, M. and Epstein, L. and Kolyvanov, K. and Mamrak, N. and King, B. and Long, Xi and Harrington, K.I.S. and Lionnet, T. and Preibisch, S.
Nature Methods 19 (12): 1563-1567. December 2022

Cardiac metabolism in HFpEF: from fuel to signalling.
Capone, F. and Sotomayor-Flores, C. and Bode, D. and Wang, R. and Rodolico, D. and Strocchi, S. and Schiattarella, G.G.
Cardiovascular Research 118 (18): 3556-3575. December 2022

A critical period of translational control during brain development at codon resolution.
Harnett, D. and Ambrozkiewicz, M.C. and Zinnall, U. and Rusanova, A. and Borisova, E. and Drescher, A.N. and Couce-Iglesias, M. and Villamil, G. and Dannenberg, R. and Imami, K. and Münster-Wandowski, A. and Fauler, B. and Mielke, T. and Selbach, M. and Landthaler, M. and Spahn, C.M.T. and Tarabykin, V. and Ohler, U. and Kraushar, M.L.
Nature Structural & Molecular Biology 29 (12): 1277-1290. December 2022

Mechanisms of spermidine-induced autophagy and geroprotection.
Hofer, S.J. and Simon, A.K. and Bergmann, M. and Eisenberg, T. and Kroemer, G. and Madeo, F.
Nature Aging 2 (12): 1112-1129. December 2022

Inflammation in children with chronic kidney disease linked to gut dysbiosis and metabolite imbalance.
Holle, J. and Bartolomaeus, H. and Löber, U. and Behrens, F. and Bartolomaeus, T.U.P. and Anandakumar, H. and Wimmer, M. and Vu, D.L. and Kuhring, M. and Brüning, U. and Maifeld, A. and Geisberger, S. and Kempa, S. and Schumacher, F. and Kleuser, B. and Bufler, P. and Querfeld, U. and Kitschke, S. and Engler, D. and Kuhrt, L.D. and Drechsel, O. and Eckardt, K.U. and Forslund, S. and Thürmer, A. and McParland, V. and Kirwan, J. and Wilck, N. and Mueller, D.
Journal of the American Society of Nephrology 33 (12): 2259-2275. December 2022

Urinary single-cell sequencing captures kidney injury and repair processes in human acute kidney injury.
Klocke, J. and Kim, S.J. and Skopnik, C.M. and Hinze, C. and Boltengagen, A. and Metzke, D. and Grothgar, E. and Prskalo, L. and Wagner, L. and Freund, P. and Görlich, N. and Muench, F. and Schmidt-Ott, K.M. and Mashreghi, M.F. and Kocks, C. and Eckardt, K.U. and Rajewsky, N. and Enghard, P.
Kidney International 102 (6): 1359-1370. December 2022

Tuning the 3D microenvironment of reprogrammed tubule cells enhances biomimetic modeling of polycystic kidney disease.
Pichler, R. and Rizzo, L. and Tröndle, K. and Bühler, M. and Brucker, H. and Müller, A.L. and Grand, K. and Farè, S. and Viau, A. and Kaminski, M.M. and Kuehn, E.W. and Koch, F. and Zimmermann, S. and Koltay, P. and Lienkamp, S.S.
Biomaterials 291 : 121910. December 2022

The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants.
Rothenberger, S. and Hurdiss, D.L. and Walser, M. and Malvezzi, F. and Mayor, J. and Ryter, S. and Moreno, H. and Liechti, N. and Bosshart, A. and Iss, C. and Calabro, V. and Cornelius, A. and Hospodarsch, T. and Neculcea, A. and Looser, T. and Schlegel, A. and Fontaine, S. and Villemagne, D. and Paladino, M. and Schiegg, D. and Mangold, S. and Reichen, C. and Radom, F. and Kaufmann, Y. and Schaible, D. and Schlegel, I. and Zitt, C. and Sigrist, G. and Straumann, M. and Wolter, J. and Comby, M. and Sacarcelik, F. and Drulyte, I. and Lyoo, H. and Wang, C. and Li, W. and Du, W. and Binz, H.K. and Herrup, R. and Lusvarghi, S. and Neerukonda, S.N. and Vassell, R. and Wang, W. and Adler, J.M. and Eschke, K. and Nascimento, M. and Abdelgawad, A. and Gruber, A.D. and Bushe, J. and Kershaw, O. and Knutson, C.G. and Balavenkatraman, K.K. and Ramanathan, K. and Wyler, E. and Teixeira Alves, L.G. and Lewis, S. and Watson, R. and Haeuptle, M.A. and Zürcher, A. and Dawson, K.M. and Steiner, D. and Weiss, C.D. and Amstutz, P. and van Kuppeveld, F.J.M. and Stumpp, M.T. and Bosch, B.J. and Engler, O. and Trimpert, J.
Nature Biotechnology 40 (12): 1845-1854. December 2022

Extrachromosomal DNA amplifications in cancer.
Yi, E. and Chamorro González, R. and Henssen, A.G. and Verhaak, R.G.W.
Nature Reviews Genetics 23 (12): 760-771. December 2022

Cell type diversity in a developing octopus brain.
Styfhals, R. and Zolotarov, G. and Hulselmans, G. and Spanier, K.I. and Poovathingal, S. and Elagoz, A.M. and De Winter, S. and Deryckere, A. and Rajewsky, N. and Ponte, G. and Fiorito, G. and Aerts, S. and Seuntjens, E.
Nature Communications 13 (1): 7392. 30 November 2022

Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki, F. and Bjordahl, R. and Goodridge, J.P. and Mahmood, S. and Gaidarova, S. and Abujarour, R. and Davis, Z.B. and Merino, A. and Tuininga, K. and Wang, H. and Kumar, A. and Groff, B. and Witty, A. and Bonello, G. and Huffman, J. and Dailey, T. and Lee, T.T. and Malmberg, K.J. and Walcheck, B. and Höpken, U. and Rehm, A. and Valamehr, B. and Miller, J.S.
Nature Communications 13 (1): 7341. 29 November 2022

DNA methylation-based classification of sinonasal tumors.
Jurmeister, P. and Glöß, S. and Roller, R. and Leitheiser, M. and Schmid, S. and Mochmann, L.H. and Payá Capilla, E. and Fritz, R. and Dittmayer, C. and Friedrich, C. and Thieme, A. and Keyl, P. and Jarosch, A. and Schallenberg, S. and Bläker, H. and Hoffmann, I. and Vollbrecht, C. and Lehmann, A. and Hummel, M. and Heim, D. and Haji, M. and Harter, P. and Englert, B. and Frank, S. and Hench, J. and Paulus, W. and Hasselblatt, M. and Hartmann, W. and Dohmen, H. and Keber, U. and Jank, P. and Denkert, C. and Stadelmann, C. and Bremmer, F. and Richter, A. and Wefers, A. and Ribbat-Idel, J. and Perner, S. and Idel, C. and Chiariotti, L. and Della Monica, R. and Marinelli, A. and Schüller, U. and Bockmayr, M. and Liu, J. and Lund, V.J. and Forster, M. and Lechner, M. and Lorenzo-Guerra, S.L. and Hermsen, M. and Johann, P.D. and Agaimy, A. and Seegerer, P. and Koch, A. and Heppner, F. and Pfister, S.M. and Jones, D.T.W. and Sill, M. and von Deimling, A. and Snuderl, M. and Müller, K.R. and Forgó, E. and Howitt, B.E. and Mertins, P. and Klauschen, F. and Capper, D.
Nature Communications 13 (1): 7148. 28 November 2022

MicroRNAs are deeply linked to the emergence of the complex octopus brain.
Zolotarov, G. and Fromm, B. and Legnini, I. and Ayoub, S. and Polese, G. and Maselli, V. and Chabot, P.J. and Vinther, J. and Styfhals, R. and Seuntjens, E. and Di Cosmo, A. and Peterson, K.J. and Rajewsky, N.
Science Advances 8 (47): eadd9938. 25 November 2022

Non-redundant functions of group 2 innate lymphoid cells.
Jarick, K.J. and Topczewska, P.M. and Jakob, M.O. and Yano, H. and Arifuzzaman, M. and Gao, X. and Boulekou, S. and Stokic-Trtica, V. and Leclère, P.S. and Preußer, A. and Rompe, Z.A. and Stamm, A. and Tsou, A.M. and Chu, C. and Heinrich, F.R. and Guerra, G.M. and Durek, P. and Ivanov, A. and Beule, D. and Helfrich, S. and Duerr, C.U. and Kühl, A.A. and Stehle, C. and Romagnani, C. and Mashreghi, M.F. and Diefenbach, A. and Artis, D. and Klose, C.S.N.
Nature 611 (7937): 794-800. 24 November 2022

Single-cell multi-omics allows functional characterization of structural variants.
Korbel, J.O. and Sanders, A.D.
Nature Biotechnology 24 November 2022

Identification of environmental factors that promote intestinal inflammation.
Sanmarco, L.M. and Chao, C.C. and Wang, Y.C. and Kenison, J.E. and Li, Z. and Rone, J.M. and Rejano-Gordillo, C.M. and Polonio, C.M. and Gutierrez-Vazquez, C. and Piester, G. and Plasencia, A. and Li, L. and Giovannoni, F. and Lee, H.G. and Faust Akl, C. and Wheeler, M.A. and Mascanfroni, I. and Jaronen, M. and Alsuwailm, M. and Hewson, P. and Yeste, A. and Andersen, B.M. and Franks, D.G. and Huang, C.J. and Ekwudo, M. and Tjon, E.C. and Rothhammer, V. and Takenaka, M. and de Lima, K.A. and Linnerbauer, M. and Guo, L. and Covacu, R. and Queva, H. and Fonseca-Castro, P.H. and Bladi, M.A. and Cox, L.M. and Hodgetts, K.J. and Hahn, M.E. and Mildner, A. and Korzenik, J. and Hauser, R. and Snapper, S.B. and Quintana, F.J.
Nature 611 (7937): 801-809. 24 November 2022

Semi-automated assembly of high-quality diploid human reference genomes.
Jarvis, E.D. and Formenti, G. and Rhie, A. and Guarracino, A. and Yang, C. and Wood, J. and Tracey, A. and Thibaud-Nissen, F. and Vollger, M.R. and Porubsky, D. and Cheng, H. and Asri, M. and Logsdon, G.A. and Carnevali, P. and Chaisson, M.J.P. and Chin, C.S. and Cody, S. and Collins, J. and Ebert, P. and Escalona, M. and Fedrigo, O. and Fulton, R.S. and Fulton, L.L. and Garg, S. and Gerton, J.L. and Ghurye, J. and Granat, A. and Green, R.E. and Harvey, W. and Hasenfeld, P. and Hastie, A. and Haukness, M. and Jaeger, E.B. and Jain, M. and Kirsche, M. and Kolmogorov, M. and Korbel, J.O. and Koren, S. and Korlach, J. and Lee, J. and Li, D. and Lindsay, T. and Lucas, J. and Luo, F. and Marschall, T. and Mitchell, M.W. and McDaniel, J. and Nie, F. and Olsen, H.E. and Olson, N.D. and Pesout, T. and Potapova, T. and Puiu, D. and Regier, A. and Ruan, J. and Salzberg, S.L. and Sanders, A.D. and Schatz, M.C. and Schmitt, A. and Schneider, V.A. and Selvaraj, S. and Shafin, K. and Shumate, A. and Stitziel, N.O. and Stober, C. and Torrance, J. and Wagner, J. and Wang, J. and Wenger, A. and Xiao, C. and Zimin, A.V. and Zhang, G. and Wang, T. and Li, H. and Garrison, E. and Haussler, D. and Hall, I. and Zook, J.M. and Eichler, E.E. and Phillippy, A.M. and Paten, B. and Howe, K. and Miga, K.H.
Nature 611 (7936): 519-531. 17 November 2022

MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.
Kaufmann, T.L. and Petkovic, M. and Watkins, T.B.K. and Colliver, E.C. and Laskina, S. and Thapa, N. and Minussi, D.C. and Navin, N. and Swanton, C. and Van Loo, P. and Haase, K. and Tarabichi, M. and Schwarz, R.F.
Genome Biology 23 (1): 241. 14 November 2022

pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation.
Boix, O. and Martinez, M. and Vidal, S. and Giménez-Alejandre, M. and Palenzuela, L. and Lorenzo-Sanz, L. and Quevedo, L. and Moscoso, O. and Ruiz-Orera, J. and Ximénez-Embún, P. and Ciriaco, N. and Nuciforo, P. and Stephan-Otto Attolini, C. and Albà, M.M. and Muñoz, J. and Tian, T.V. and Varela, I. and Vivancos, A. and Ramón Y Cajal, S. and Muñoz, P. and Rivas, C. and Abad, M.
Nature Communications 13 (1): 6840. 11 November 2022

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S. and Company, C. and Song, K. and Lowenstein, E.D. and Riedel, L. and Birchmeier, C. and Gargiulo, G. and Zampieri, N.
Nature Communications 13 (1): 6867. 11 November 2022

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
Belda, E. and Voland, L. and Tremaroli, V. and Falony, G. and Adriouch, S. and Assmann, K.E. and Prifiti, E. and Aron-Wisnewsky, J. and Debédat, J. and Le Roy, T. and Nielsen, T. and Amouyal, C. and André, S. and Andreelli, F. and Blüher, M. and Chakaroun, R. and Chilloux, J. and Coelho, L.P. and Dao, M.C. and Das, P. and Fellahi, S. and Forslund, S. and Galleron, N. and Hansen, T.H. and Holmes, B. and Ji, B. and Krogh Pedersen, H. and Le, P. and Le Chatelier, E. and Lewinter, C. and Mannerås-Holm, L. and Marquet, F. and Myridakis, A. and Pelloux, V. and Pons, N. and Quinquis, B. and Rouault, C. and Roume, H. and Salem, J.E. and Sokolovska, N. and Søndertoft, N.B. and Touch, S. and Vieira-Silva, S. and Galan, P. and Holst, J. and Gøtze, J.P. and Køber, L. and Vestergaard, H. and Hansen, T. and Hercberg, S. and Oppert, J.M. and Nielsen, J. and Letunic, I. and Dumas, M.E. and Stumvoll, M. and Pedersen, O.B. and Bork, P. and Ehrlich, S.D. and Zucker, J.D. and Bäckhed, F. and Raes, J. and Clément, K.
Gut 71 (12): 2463-2480. 7 November 2022

Microglia states and nomenclature: A field at its crossroads.
Paolicelli, R.C. and Sierra, A. and Stevens, B. and Tremblay, M.E. and Aguzzi, A. and Ajami, B. and Amit, I. and Audinat, E. and Bechmann, I. and Bennett, M. and Bennett, F. and Bessis, A. and Biber, K. and Bilbo, S. and Blurton-Jones, M. and Boddeke, E. and Brites, D. and Brône, B. and Brown, G.C. and Butovsky, O. and Carson, M.J. and Castellano, B. and Colonna, M. and Cowley, S.A. and Cunningham, C. and Davalos, D. and De Jager, P.L. and de Strooper, B. and Denes, A. and Eggen, B.J.L. and Eyo, U. and Galea, E. and Garel, S. and Ginhoux, F. and Glass, C.K. and Gokce, O. and Gomez-Nicola, D. and González, B. and Gordon, S. and Graeber, M.B. and Greenhalgh, A.D. and Gressens, P. and Greter, M. and Gutmann, D.H. and Haass, C. and Heneka, M.T. and Heppner, F.L. and Hong, S. and Hume, D.A. and Jung, S. and Kettenmann, H. and Kipnis, J. and Koyama, R. and Lemke, G. and Lynch, M. and Majewska, A. and Malcangio, M. and Malm, T. and Mancuso, R. and Masuda, T. and Matteoli, M. and McColl, B.W. and Miron, V.E. and Molofsky, A.V. and Monje, M. and Mracsko, E. and Nadjar, A. and Neher, J.J. and Neniskyte, U. and Neumann, H. and Noda, M. and Peng, B. and Peri, F. and Perry, V.H. and Popovich, P.G. and Pridans, C. and Priller, J. and Prinz, M. and Ragozzino, D. and Ransohoff, R.M. and Salter, M.W. and Schaefer, A. and Schafer, D.P. and Schwartz, M. and Simons, M. and Smith, C.J. and Streit, W.J. and Tay, T.L. and Tsai, L.H. and Verkhratsky, A. and von Bernhardi, R. and Wake, H. and Wittamer, V. and Wolf, S.A. and Wu, L.J. and Wyss-Coray, T.
Neuron 110 (21): 3458-3483. 2 November 2022

TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation.
Tufan, A.B. and Lazarow, K. and Kolesnichenko, M. and Sporbert, A. and von Kries, J.P. and Scheidereit, C.
EMBO Journal 41 (21): e110372. 2 November 2022

EBAG9-silencing exerts an immune checkpoint function without aggravating adverse effects.
Wirges, A. and Bunse, M. and Joedicke, J.J. and Blanc, E. and Gudipati, V. and Moles, M.W. and Shiku, H. and Beule, D. and Huppa, J.B. and Höpken, U.E. and Rehm, A.
Molecular Therapy 30 (11): 3358-3378. 2 November 2022

R-spondin-YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.
Fischer, A.S. and Müllerke, S. and Arnold, A. and Heuberger, J. and Berger, H. and Lin, M. and Mollenkopf, H.J. and Wizenty, J. and Horst, D. and Tacke, F. and Sigal, M.
Journal of Clinical Investigation 132 (21): e151363. 1 November 2022

Antibiotic resistance genes in river biofilms: a metagenomic approach toward the identification of sources and candidate hosts.
Kneis, D. and Berendonk, T.U. and Forslund, S.K. and Hess, S.
Environmental Science and Technology 56 (21): 14913-14922. 1 November 2022

Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma.
Welters, C. and Lammoglia Cobo, M.F. and Stein, C.A. and Hsu, M.T. and Ben Hamza, A. and Penter, L. and Chen, X. and Buccitelli, C. and Popp, O. and Mertins, P. and Dietze, K. and Bullinger, L. and Moosmann, A. and Blanc, E. and Beule, D. and Gerbitz, A. and Strobel, J. and Hackstein, H. and Rahn, H.P. and Dornmair, K. and Blankenstein, T. and Hansmann, L.
Cancer Immunology Research 10 (11): 1407-1419. 1 November 2022

A cFLIP-flop switch for senolysis.
Fan, D.N.Y. and Schmitt, C.A.
Nature Cancer 3 (11): 1279-1281. November 2022

The SCF/KIT axis in human mast cells: capicua acts as potent KIT repressor and ERK predominates PI3K.
Franke, K. and Kirchner, M. and Mertins, P. and Zuberbier, T. and Babina, M.
Allergy 77 (11): 3337-3349. November 2022

Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
Hung, K.L. and Luebeck, J. and Dehkordi, S.R. and Colón, C.I. and Li, R. and Wong, I.T.L. and Coruh, C. and Dharanipragada, P. and Lomeli, S.H. and Weiser, N.E. and Moriceau, G. and Zhang, X. and Bailey, C. and Houlahan, K.E. and Yang, W. and González, R.C. and Swanton, C. and Curtis, C. and Jamal-Hanjani, M. and Henssen, A.G. and Law, J.A. and Greenleaf, W.J. and Lo, R.S. and Mischel, P.S. and Bafna, V. and Chang, H.Y.
Nature Genetics 54 (11): 1746–1754. November 2022

Filaggrin loss-of-function mutations are associated with persistence of egg and milk allergy.
Kalb, B. and Marenholz, I. and Jeanrenaud, A.C.S.N. and Meixner, L. and Arnau-Soler, A. and Rosillo-Salazar, O.D. and Ghauri, A. and Cibin, P. and Blümchen, K. and Schlags, R. and Hansen, G. and Seidenberg, J. and Keil, T. and Lau, S. and Niggemann, B. and Beyer, K. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 150 (5): 1125-1134. November 2022

The Case: Is this hemolytic uremic syndrome?
Kettritz, R. and Düttmann, W. and Brand, A. and Luft, F.C.
Kidney International 102 (5): 1195-1196. November 2022

Clonal expansion and epigenetic inheritance of long-lasting NK cell memory.
Rückert, T. and Lareau, C.A. and Mashreghi, M.F. and Ludwig, L.S. and Romagnani, C.
Nature Immunology 23 (11): 1551-1563. November 2022

Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
Houwaart, Torsten and Belhaj, S. and Tawalbeh, E. and Nagels, D. and Fröhlich, Y. and Finzer, P. and Ciruela, P. and Sabrià, A. and Herrero, M. and Andrés, C. and Antón, A. and Benmoumene, A. and Asskali, D. and Haidar, H. and von Dahlen, J. and Nicolai, J. and Stiller, M. and Blum, J. and Lange, C. and Adelmann, C. and Schroer, B. and Osmers, U. and Grice, C. and Kirfel, P.P. and Jomaa, H. and Strelow, D. and Hülse, L. and Pigulla, M. and Kreuzer, P. and Tyshaieva, A. and Weber, J. and Wienemann, T. and Kohns Vasconcelos, M. and Hoffmann, K. and Lübke, N. and Hauka, S. and Andree, M. and Scholz, C.J. and Jazmati, N. and Göbels, K. and Zotz, R. and Pfeffer, K. and Timm, J. and Ehlkes, L. and Walker, A. and Dilthey, A.T.
Eurosurveillance 27 (43): 2101089. 27 October 2022

H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2(+) patients with diffuse midline glioma.
Immisch, L. and Papafotiou, G. and Popp, O. and Mertins, P. and Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 10 (10): e005535. 27 October 2022

Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.
Ortiz-Zapater, E. and Bagley, D.C. and Hernandez, V.L. and Roberts, L.B. and Maguire, T.J.A. and Voss, F. and Mertins, P. and Kirchner, M. and Peset-Martin, I. and Woszczek, G. and Rosenblatt, J. and Gotthardt, M. and Santis, G. and Parsons, M.
Nature Communications 13 (1): 6407. 27 October 2022

The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
Paulmann, C. and Spallek, R. and Karpiuk, O. and Heider, M. and Schäffer, I. and Zecha, J. and Klaeger, S. and Walzik, M. and Öllinger, R. and Engleitner, T. and Wirth, M. and Keller, U. and Krönke, J. and Rudelius, M. and Kossatz, S. and Rad, R. and Kuster, B. and Bassermann, F.
EMBO Journal 41 (20): e110871. 17 October 2022

Cluster-independent marker feature identification from single-cell omics data using SEMITONES.
Vlot, A.H.C. and Maghsudi, S. and Ohler, U.
Nucleic Acids Research 50 (18): e107. 14 October 2022

Dissecting the intracellular pancreatic tumor microbiome at single-cell level.
Schmidt, T.S.B. and Bork, P.
Cancer Cell 40 (10): 1083-1085. 10 October 2022

A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation.
Yanchus, C. and Drucker, K.L. and Kollmeyer, T.M. and Tsai, R. and Winick-Ng, W. and Liang, M. and Malik, A. and Pawling, J. and De Lorenzo, S.B. and Ali, A. and Decker, P.A. and Kosel, M.L. and Panda, A. and Al-Zahrani, K.N. and Jiang, L. and Browning, J.W.L. and Lowden, C. and Geuenich, M. and Hernandez, J.J. and Gosio, J.T. and Ahmed, M. and Loganathan, S.K. and Berman, J. and Trcka, D. and Michealraj, K.A. and Fortin, J. and Carson, B. and Hollingsworth, E.W. and Jacinto, S. and Mazrooei, P. and Zhou, L. and Elia, A. and Lupien, M. and He, H.H. and Murphy, D.J. and Wang, L. and Abyzov, A. and Dennis, J.W. and Maass, P.G. and Campbell, K. and Wilson, M.D. and Lachance, D.H. and Wrensch, M. and Wiencke, J. and Mak, T. and Pennacchio, L.A. and Dickel, D.E. and Visel, A. and Wrana, J. and Taylor, M.D. and Zadeh, G. and Dirks, P. and Eckel-Passow, J.E. and Attisano, L. and Pombo, A. and Ida, C.M. and Kvon, E.Z. and Jenkins, R.B. and Schramek, D.
Science 378 (6615): 68-78. 7 October 2022

SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.
Maharana, S. and Kretschmer, S. and Hunger, S. and Yan, X. and Kuster, D. and Traikov, S. and Zillinger, T. and Gentzel, M. and Elangovan, S. and Dasgupta, P. and Chappidi, N. and Lucas, N. and Maser, K.I. and Maatz, H. and Rapp, A. and Marchand, V. and Chang, Y.T. and Motorin, Y. and Hubner, N. and Hartmann, G. and Hyman, A.A. and Alberti, S. and Lee-Kirsch, M.A.
Molecular Cell 82 (19): 3712-3728.e10. 6 October 2022

Epigenetic "transgenerational" inheritance.
Luft, F.C.
Circulation 146 (14): 1096-1098. 4 October 2022

Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs.
Broto, M. and Kaminski, M.M. and Adrianus, C. and Kim, N. and Greensmith, R. and Dissanayake-Perera, S. and Schubert, A.J. and Tan, X. and Kim, H. and Dighe, A.S. and Collins, J.J. and Stevens, M.M.
Nature Nanotechnology 17 (10): 1120-1126. October 2022

Acute kidney injury in patients receiving pembrolizumab combination therapy versus pembrolizumab monotherapy for advanced lung cancer.
Gupta, S. and Strohbehn, I.A. and Wang, Q. and Hanna, P.E. and Seethapathy, R. and Prosek, J.M. and Herrmann, S.M. and Abudayyeh, A. and Malik, A.B. and Loew, S. and Carlos, C.A. and Chang, W.T. and Beckerman, P. and Mithani, Z. and Shah, C.V. and Renaghan, A. and de Seigneux, S. and Campedel, L. and Kitchlu, A. and Shin, D.S. and Coppock, G. and Lumlertgul, N. and Garcia, P. and Ortiz-Melo, D.I. and Rashidi, A. and Sprangers, B. and Aggarwal, V. and Benesova, K. and Jhaveri, K.D. and Cortazar, F.B. and Weins, A. and Zuo, Y. and Mooradian, M.J. and Reynolds, K.L. and Leaf, D.E. and Sise, M.E.
Kidney International 102 (4): 930-935. October 2022

The evolutionary dynamics of extrachromosomal DNA in human cancers.
Lange, J.T. and Rose, J.C. and Chen, C.Y. and Pichugin, Y. and Xie, L. and Tang, J. and Hung, K.L. and Yost, K.E. and Shi, Q. and Erb, M.L. and Rajkumar, U. and Wu, S. and Taschner-Mandl, S. and Bernkopf, M. and Swanton, C. and Liu, Z. and Huang, W. and Chang, H.Y. and Bafna, V. and Henssen, A.G. and Werner, B. and Mischel, P.S.
Nature Genetics 54 (10): 1527-1533. October 2022

Physiological functions of intracellular protein degradation.
McShane, E. and Selbach, M.
Annual Review of Cell and Developmental Biology 38 : 241-262. October 2022

Best practice standards for circular RNA research.
Nielsen, A.F. and Bindereif, A. and Bozzoni, I. and Hanan, M. and Hansen, T.B. and Irimia, M. and Kadener, S. and Kristensen, L.S. and Legnini, I. and Morlando, M. and Jarlstad Olesen, M.T. and Pasterkamp, R.J. and Preibisch, S. and Rajewsky, N. and Suenkel, C. and Kjems, J.
Nature Methods 19 (10): 1208-1220. October 2022

Framework and baseline examination of the German National Cohort (NAKO).
Peters, A. and Peters, A. and Greiser, K.H. and Göttlicher, S. and Ahrens, W. and Albrecht, M. and Bamberg, F. and Bärnighausen, T. and Becher, H. and Berger, K. and Beule, A. and Boeing, H. and Bohn, B. and Bohnert, K. and Braun, B. and Brenner, H. and Bülow, R. and Castell, S. and Damms-Machado, A. and Dörr, M. and Ebert, N. and Ecker, M. and Emmel, C. and Fischer, B. and Franzke, C.W. and Gastell, S. and Giani, G. and Günther, M. and Günther, K. and Günther, K.P. and Haerting, J. and Haug, U. and Heid, I.M. and Heier, M. and Heinemeyer, D. and Hendel, T. and Herbolsheimer, F. and Hirsch, J. and Hoffmann, W. and Holleczek, B. and Hölling, H. and Hörlein, A. and Jöckel, K.H. and Kaaks, R. and Karch, A. and Karrasch, S. and Kartschmit, N. and Kauczor, H.U. and Keil, T. and Kemmling, Y. and Klee, B. and Klüppelholz, B. and Kluttig, A. and Kofink, L. and Köttgen, A. and Kraft, D. and Krause, G. and Kretz, L. and Krist, L. and Kühnisch, J. and Kuß, O. and Legath, N. and Lehnich, A.T. and Leitzmann, M. and Lieb, W. and Linseisen, J. and Loeffler, M. and Macdonald, A. and Maier-Hein, K.H. and Mangold, N. and Meinke-Franze, C. and Meisinger, C. and Melzer, J. and Mergarten, B. and Michels, K.B. and Mikolajczyk, R. and Moebus, S. and Mueller, U. and Nauck, M. and Niendorf, T. and Nikolaou, K. and Obi, N. and Ostrzinski, S. and Panreck, L. and Pigeot, I. and Pischon, T. and Pschibul-Thamm, I. and Rathmann, W. and Reineke, A. and Roloff, S. and Rujescu, D. and Rupf, S. and Sander, O. and Schikowski, T. and Schipf, S. and Schirmacher, P. and Schlett, C.L. and Schmidt, B. and Schmidt, G. and Schmidt, M. and Schöne, G. and Schulz, H. and Schulze, M.B. and Schweig, A. and Sedlmeier, A.M. and Selder, S. and Six-Merker, J. and Sowade, R. and Stang, A. and Stegle, O. and Steindorf, K. and Stübs, G. and Swart, E. and Teismann, H. and Thiele, I. and Thierry, S. and Ueffing, M. and Völzke, H. and Waniek, S. and Weber, A. and Werner, N. and Wichmann, H.E. and Willich, S.N. and Wirkner, K. and Wolf, K. and Wolff, R. and Zeeb, H. and Zinkhan, M. and Zschocke, J.
European Journal of Epidemiology 37 (10): 1107-1124. October 2022

A novel gene controls a new structure: piggyBac transposable element-derived 1, unique to mammals, controls mammal-specific neuronal paraspeckles.
Raskó, T. and Pande, A. and Radscheit, K. and Zink, A. and Singh, M. and Sommer, C. and Wachtl, G. and Kolacsek, O. and Inak, G. and Szvetnik, A. and Petrakis, S. and Bunse, M. and Bansal, V. and Selbach, M. and Orbán, T.I. and Prigione, A. and Hurst, L.D. and Izsvák, Z.
Molecular Biology and Evolution 39 (10): msac175. October 2022

Senescence and cancer - role and therapeutic opportunities.
Schmitt, C.A. and Wang, B. and Demaria, M.
Nature Reviews Clinical oncology 19 (10): 619–636. October 2022

Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes.
Ringel, A.R. and Szabo, Q. and Chiariello, A.M. and Chudzik, K. and Schöpflin, R. and Rothe, P. and Mattei, A.L. and Zehnder, To. and Harnett, D. and Laupert, V. and Bianco, S. and Hetzel, S. and Glaser, J. and Phan, M.H.Q. and Schindler, M. and Ibrahim, D.M. and Paliou, C. and Esposito, A. and Prada-Medina, C.A. and Haas, S.A. and Giere, P. and Vingron, M. and Wittler, L. and Meissner, A. and Nicodemi, M. and Cavalli, G. and Bantignies, F. and Mundlos, S. and Robson, M.I.
Cell 185 (20): 3689-3704. 29 September 2022

Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Perea-Gil, I. and Seeger, T. and Bruyneel, A.A.N. and Termglinchan, V. and Monte, E. and Lim, E.W. and Vadgama, N. and Furihata, T. and Gavidia, A.A. and Arthur Ataam, J. and Bharucha, N. and Martinez-Amador, N. and Ameen, M. and Nair, P. and Serrano, R. and Kaur, B. and Feyen, D.A.M. and Diecke, S. and Snyder, M.P. and Metallo, C.M. and Mercola, M. and Karakikes, I.
European Heart Journal 43 (36): 3477-3489. 21 September 2022

The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G. and Vanzo, R. and Amitash, S. and Martín-Doncel, E. and Coscia, F. and Mund, A. and Lerdrup, M. and Benada, J. and Boos, D. and Toledo, L.
Molecular Cell 82 (18): 3350-3365. 15 September 2022

Translating plasma sodium, stores, and hydration state from mouse to man.
Luft, F.C.
European Heart Journal 43 (35): 3349-3351. 14 September 2022

Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.
Poetz, F. and Lebedeva, S. and Schott, J. and Lindner, D. and Ohler, U. and Stoecklin, G.
Genome Biology 23 (1): 193. 12 September 2022

Cellular hierarchies predict drug response in acute myeloid leukemia.
Raffel, S. and Velten, L. and Haas, S.
Cancer Cell 40 (9): 917-919. 12 September 2022

Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.
Monti, R. and Rautenstrauch, P. and Ghanbari, M. and James, A.R. and Kirchler, M. and Ohler, U. and Konigorski, S. and Lippert, C.
Nature Communications 13 (1): 5332. 10 September 2022

Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury.
Hinze, C. and Kocks, C. and Leiz, J. and Karaiskos, N. and Boltengagen, A. and Cao, S. and Skopnik, C.M. and Klocke, J. and Hardenberg, J.H. and Stockmann, H. and Gotthardt, I. and Obermayer, B. and Haghverdi, L. and Wyler, E. and Landthaler, M. and Bachmann, S. and Hocke, A.C. and Corman, V. and Busch, J. and Schneider, W. and Himmerkus, N. and Bleich, M. and Eckardt, K.U. and Enghard, P. and Rajewsky, N. and Schmidt-Ott, K.M.
Genome Medicine 14 (1): 103. 9 September 2022

Different classes of genomic inserts contribute to human antibody diversity.
Lebedin, M. and Foglierini, M. and Khorkova, S. and Vázquez García, C. and Ratswohl, C. and Davydov, A.N. and Turchaninova, M.A. and Daubenberger, C. and Chudakov, D.M. and Lanzavecchia, A. and de la Rosa, K.
Proceedings of the National Academy of Sciences of the United States of America 119 (36): e2205470119. 6 September 2022

Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T. and Funck, K. and Wollweber, F. and Lisicki, E. and von der Malsburg, K. and von der Malsburg, A. and Laborenz, J. and Noel, J.K. and Hessenberger, M. and Jungbluth, S. and Bernert, C. and Kunz, S. and Riedel, D. and Lilie, H. and Jakobs, S. and van der Laan, M. and Daumke, O.
Science Advances 8 (35): eabo4946. 2 September 2022

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.
Zhou, D. and Borsa, M. and Puleston, D.J. and Zellner, S. and Capera, J. and Sanderson, S. and Schifferer, M. and Hester, S.S. and Ge, X. and Fischer, R. and Jostins, L. and Behrends, C. and Alsaleh, G. and Simon, A.K.
Nature Communications 13 (1): 5174. 2 September 2022

C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages.
Dörr, D. and Obermayer, B. and Weiner, J.M. and Zimmermann, K. and Anania, C. and Wagner, L.K. and Lyras, E.M. and Sapozhnikova, V. and Lara-Astiaso, D. and Prósper, F. and Lang, R. and Lupiáñez, D.G. and Beule, D. and Höpken, U.E. and Leutz, A. and Mildner, A.
Science Immunology 7 (75): eabj0140. September 2022

Evaluating metallic artefact of biodegradable magnesium-based implants in magnetic resonance imaging.
Espiritu, J. and Berangi, M. and Yiannakou, C. and Silva, E. and Francischello, R. and Kuehne, A. and Niendorf, T. and Könneker, S. and Willumeit-Römer, R. and Seitz, J.M.
Bioactive Materials 15 : 382-391. September 2022

Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.
Jahn, N. and Jahn, E. and Saadati, M. and Bullinger, L. and Larson, R.A. and Ottone, T. and Amadori, S. and Prior, T.W. and Brandwein, J.M. and Appelbaum, F.R. and Medeiros, B.C. and Tallman, M.S. and Ehninger, G. and Heuser, M. and Ganser, A. and Pallaud, C. and Gathmann, I. and Krzykalla, J. and Benner, A. and Bloomfield, C.D. and Thiede, C. and Stone, R.M. and Döhner, H. and Döhner, K.
Leukemia 36 (9): 2218-2227. September 2022

SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt, L. and Braun, J. and Fauchere, F. and Vanshylla, K. and Loyal, L. and Henze, L. and Kruse, B. and Dingeldey, M. and Jürchott, K. and Mangold, M. and Maraj, A. and Braginets, A. and Böttcher, C. and Nitsche, A. and de la Rosa, K. and Ratswohl, C. and Sawitzki, B. and Holenya, P. and Reimer, U. and Sander, L.E. and Klein, F. and Paul, F. and Bellmann-Strobl, J. and Thiel, A. and Giesecke-Thiel, C.
Journal of Neurology Neurosurgery and Psychiatry 93 (9): 960-971. September 2022

Drivers and determinants of strain dynamics following fecal microbiota transplantation.
Schmidt, T.S.B. and Li, S.S. and Maistrenko, O.M. and Akanni, W. and Coelho, L.P. and Dolai, S. and Fullam, A. and Glazek, A.M. and Hercog, R. and Herrema, H. and Jung, F. and Kandels, S. and Orakov, A. and Thielemann, R. and von Stetten, M. and Van Rossum, T. and Benes, V. and Borody, T.J. and de Vos, W.M. and Ponsioen, C.Y. and Nieuwdorp, M. and Bork, P.
Nature Medicine 28 (9): 1902-1912. September 2022

Precision medicine in myeloid malignancies.
Westermann, J. and Bullinger, L.
Seminars in Cancer Biology 84 : 153-169. September 2022

Mutations in TAF8 cause a neurodegenerative disorder.
Wong, K.M. and Jepsen, W.M. and Efthymiou, S. and Salpietro, V. and Sanchez-Castillo, M. and Yip, J. and Kriouile, Y. and Diegmann, S. and Dreha-Kulaczewski, S. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Toosi, M.B. and Akhondian, J. and Ghayoor Karimiani, E. and Hummel-Abmeier, H. and Huppke, B. and Houlden, H. and Gärtner, J. and Maroofian, R. and Huppke, P.
Brain 145 (9): 3022-3034. September 2022

PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.
Garces de Los Fayos Alonso, I. and Zujo, L. and Wiest, I. and Kodajova, P. and Timelthaler, G. and Edtmayer, S. and Zrimšek, M. and Kollmann, S. and Giordano, C. and Kothmayer, M. and Neubauer, H.A. and Dey, S. and Schlederer, M. and Schmalzbauer, B.S. and Limberger, T. and Probst, C. and Pusch, O. and Högler, S. and Tangermann, S. and Merkel, O. and Schiefer, A.I. and Kornauth, C. and Prutsch, N. and Zimmerman, M. and Abraham, B. and Anagnostopoulos, J. and Quintanilla-Martinez, L. and Mathas, S. and Wolf, P. and Stoiber, D. and Staber, P.B. and Egger, G. and Klapper, W. and Woessmann, W. and Look, T.A. and Gunning, P. and Turner, S.D. and Moriggl, R. and Lagger, S. and Kenner, L.
Molecular Cancer 21 (1): 172. 31 August 2022

ShapeSorter: a fully probabilistic method for detecting conserved RNA structure features supported by SHAPE evidence.
Tsybulskyi, V. and Meyer, I.M.
Nucleic Acids Research 50 (15): e85. 26 August 2022

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019.
Tran, K.B. and Lang, J.J. and Compton, K. and Xu, R. and Acheson, A.R. and Henrikson, H.J. and Kocarnik, J.M. and Penberthy, L. and Aali, A. and Abbas, Q. and Abbasi, B. and Abbasi-Kangevari, M. and Abbasi-Kangevari, Z. and Abbastabar, H. and Abdelmasseh, M. and Abd-Elsalam, S. and Abdelwahab, A.A. and Abdoli, G. and Abdulkadir, H.A. and Abedi, A. and Abegaz, K.H. and Abidi, H. and Aboagye, R.G. and Abolhassani, H. and Absalan, A. and Abtew, Yo.D. and Abubaker Ali, H. and Abu-Gharbieh, E. and Achappa, B. and Acuna, J.M. and Addison, D. and Addo, I.Y. and Adegboye, O.A. and Adesina, M.A. and Adnan, M. and Adnani, Q.E.S. and Advani, S.M. and Afrin, S. and Afzal, M.S. and Aggarwal, M. and Ahinkorah, B.O. and Ahmad, A.R. and Ahmad, R. and Ahmad, S. and Ahmad, S. and Ahmadi, S. and Ahmed, H. and Ahmed, L.A. and Ahmed, M.B. and Ahmed Rashid, T. and Aiman, W. and Ajami, M. and Akalu, G.T. and Akbarzadeh-Khiavi, M. and Aklilu, A. and Akonde, M. and Akunna, C.J. and Al Hamad, H. and Alahdab, F. and Alanezi, F.M. and Alanzi, T.M. and Alessy, S.A. and Algammal, A.M. and Al-Hanawi, M.K. and Alhassan, R.K. and Ali, B.A. and Ali, L. and Ali, S.S. and Alimohamadi, Y. and Alipour, V. and Aljunid, S.M. and Alkhayyat, M. and Al-Maweri, S.A.A. and Almustanyir, S. and Alonso, N. and Alqalyoobi, S. and Al-Raddadi, R.M. and Al-Rifai, R.H.H. and Al-Sabah, S.K. and Al-Tammemi, A.B. and Altawalah, H. and Alvis-Guzman, N. and Amare, F. and Ameyaw, E.K. and Aminian Dehkordi, J.J. and Amirzade-Iranaq, M.H. and Amu, H. and Amusa, G.A. and Ancuceanu, R. and Anderson, J.A. and Animut, Y.A. and Anoushiravani, A. and Anoushirvani, A.A. and Ansari-Moghaddam, A. and Ansha, M.G. and Antony, B. and Antwi, M.H. and Anwar, S.L. and Anwer, R. and Anyasodor, A.E. and Arabloo, J. and Arab-Zozani, M. and Aremu, O. and Argaw, A.M. and Ariffin, H. and Aripov, T. and Arshad, M. and Artaman, A. and Arulappan, J. and Aruleba, R.T. and Aryannejad, A. and Asaad, M. and Asemahagn, M.A. and Asemi, Z. and Asghari-Jafarabadi, M. and Ashraf, T. and Assadi, R. and Athar, M. and Athari, S.S. and Atout, M.M.W. and Attia, S. and Aujayeb, A. and Ausloos, M. and Avila-Burgos, L. and Awedew, A.F. and Awoke, M.A. and Awoke, T. and Ayala Quintanilla, B.P. and Ayana, T.M. and Ayen, S.S. and Azadi, D. and Azadnajafabad, S. and Azami-Aghdash, S. and Azanaw, M.M. and Azangou-Khyavy, M. and Azari Jafari, A. and Azizi, H. and Azzam, A.Y.Y. and Babajani, A. and Badar, M. and Badiye, A.D. and Baghcheghi, N. and Bagheri, N. and Bagherieh, S. and Bahadory, S. and Baig, A.A. and Baker, J.L. and Bakhtiari, A. and Bakshi, R.K. and Banach, M. and Banerjee, I. and Bardhan, M. and Barone-Adesi, F. and Barra, F. and Barrow, A. and Bashir, N.Z. and Bashiri, A. and Basu, S. and Batiha, A.M.M. and Begum, A. and Bekele, A.B. and Belay, A.S. and Belete, M.A. and Belgaumi, U.I. and Bell, A.W. and Belo, L. and Benzian, H. and Berhie, A.Y. and Bermudez, A.N.C. and Bernabe, E. and Bhagavathula, A.S. and Bhala, N. and Bhandari, B.B. and Bhardwaj, N. and Bhardwaj, P. and Bhattacharyya, K. and Bhojaraja, V.S. and Bhuyan, S.S. and Bibi, S. and Bilchut, A.H. and Bintoro, B.S. and Biondi, A. and Birega, M.G.B. and Birhan, H.E. and Bjørge, T. and Blyuss, O. and Bodicha, B.B.A. and Bolla, S.R. and Boloor, A. and Bosetti, C. and Braithwaite, D. and Brauer, M. and Brenner, H. and Briko, A.N. and Briko, N.I. and Buchanan, C.M. and Bulamu, N.B. and Bustamante-Teixeira, M.T. and Butt, M.H. and Butt, N.S. and Butt, Z.A. and Caetano dos Santos, F.L. and Cámera, L.A. and Cao, C. and Cao, Y. and Carreras, G. and Carvalho, M. and Cembranel, F. and Cerin, E. and Chakraborty, P.A. and Charalampous, P. and Chattu, V.K. and Chimed-Ochir, O. and Chirinos-Caceres, J.L. and Cho, D.Y. and Cho, W.C.S. and Christopher, D.J. and Chu, D.T. and Chukwu, I.S. and Cohen, A.J. and Conde, J. and Cortés, S. and Costa, V.M. and Cruz-Martins, N. and Culbreth, G.T. and Dadras, O. and Dagnaw, F.T. and Dahlawi, S.M.A and Dai, X. and Dandona, L. and Dandona, R. and Daneshpajouhnejad, P. and Danielewicz, A. and Dao, A.T.M. and Darvishi Cheshmeh Soltani, R. and Darwesh, A.M. and Das, S. and Davitoiu, D.V. and Davtalab Esmaeili, E. and De la Hoz, F.P. and Debela, S.A. and Dehghan, A. and Demisse, B. and Demisse, F.W. and Denova-Gutiérrez, E. and Derakhshani, A. and Derbew Molla, M. and Dereje, D. and Deribe, K.S. and Desai, R. and Desalegn, M.D. and Dessalegn, F.N. and Dessalegni, S.A.A. and Dessie, G. and Desta, A.A. and Dewan, S.M.R. and Dharmaratne, S.D. and Dhimal, M. and Dianatinasab, M. and Diao, N. and Diaz, D. and Digesa, L.E. and Dixit, S.G. and Doaei, S. and Doan, L.P. and Doku, P.N. and Dongarwar, D. and dos Santos, W.M. and Driscoll, T.R. and Dsouza, H.L. and Durojaiye, O.C. and Edalati, S. and Eghbalian, F. and Ehsani-Chimeh, E. and Eini, E. and Ekholuenetale, M. and Ekundayo, T.C. and Ekwueme, D.U. and El Tantawi, M. and Elbahnasawy, M.A. and Elbarazi, I. and Elghazaly, H. and Elhadi, M. and El-Huneidi, W. and Emamian, M.H. and Engelbert Bain, L. and Enyew, D.B. and Erkhembayar, R. and Eshetu, T. and Eshrati, B. and Eskandarieh, S. and Espinosa-Montero, J. and Etaee, F. and Etemadimanesh, A. and Eyayu, T. and Ezeonwumelu, I.J. and Ezzikouri, S. and Fagbamigbe, A.F. and Fahimi, S. and Fakhradiyev, I.R. and Faraon, E.J.A. and Fares, J. and Farmany, A. and Farooque, U. and Farrokhpour, H. and Fasanmi, A.O. and Fatehizadeh, A. and Fatima, W. and Fattahi, H. and Fekadu, G. and Feleke, B.E. and Ferrari, A.A. and Ferrero, S. and Ferro Desideri, L. and Filip, I. and Fischer, F. and Foroumadi, R. and Foroutan, M. and Fukumoto, T. and Gaal, P.A. and Gad, M.M. and Gadanya, M.A. and Gaipov, A. and Galehdar, N. and Gallus, S. and Garg, T. and Gaspar Fonseca, M. and Gebremariam, Y.H. and Gebremeskel, T.G. and Gebremichael, M.A. and Geda, Y.F. and Gela, Y.Y. and Gemeda, B.N.B. and Getachew, M. and Getachew, M.E. and Ghaffari, K. and Ghafourifard, M. and Ghamari, S.H. and Ghasemi Nour, M. and Ghassemi, F. and Ghimire, A. and Ghith, N. and Gholamalizadeh, M. and Gholizadeh Navashenaq, J. and Ghozy, S. and Gilani, S.A. and Gill, P.S. and Ginindza, T.G. and Gizaw, A.T.T. and Glasbey, J.C. and Godos, J. and Goel, A. and Golechha, M. and Goleij, P. and Golinelli, D. and Golitaleb, M. and Gorini, G. and Goulart, B.N.G. and Grosso, G. and Guadie, H.A. and Gubari, M.I.M. and Gudayu, T.W. and Guerra, M.R. and Gunawardane, D.A. and Gupta, B. and Gupta, S. and Gupta, V.B. and Gupta, V.K. and Gurara, M.K. and Guta, A. and Habibzadeh, P. and Haddadi Avval, A. and Hafezi-Nejad, N. and Hajj Ali, A. and Haj-Mirzaian, A. and Halboub, E.S. and Halimi, A. and Halwani, R. and Hamadeh, R.R. and Hameed, S. and Hamidi, S. and Hanif, A. and Hariri, S. and Harlianto, N.I. and Haro, J.M. and Hartono, R.K. and Hasaballah, A.I. and Hasan, S.M.M. and Hasani, H. and Hashemi, S.M. and Hassan, A.M. and Hassanipour, S. and Hayat, K. and Heidari, G. and Heidari, M. and Heidarymeybodi, Z. and Herrera-Serna, B.Y. and Herteliu, C. and Hezam, K. and Hiraike, Y. and Hlongwa, M.M. and Holla, R. and Holm, M. and Horita, N. and Hoseini, M. and Hossain, M.M. and Hossain, M.B.H. and Hosseini, M.S. and Hosseinzadeh, A. and Hosseinzadeh, M. and Hostiuc, M. and Hostiuc, S. and Househ, M. and Huang, J. and Hugo, F.N. and Humayun, A. and Hussain, S. and Hussein, N.R. and Hwang, B.F. and Ibitoye, S.E. and Iftikhar, P.M. and Ikuta, K.S. and Ilesanmi, O.St. and Ilic, I.M. and Ilic, M.D. and Immurana, M. and Innos, K. and Iranpour, P. and Irham, L.M. and Islam, M.S. and Islam, R.M. and Islami, F. and Ismail, N.E. and Isola, G. and Iwagami, M. and J, L.M. and Jaiswal, A. and Jakovljevic, M. and Jalili, M. and Jalilian, S. and Jamshidi, E. and Jang, S.I. and Jani, C.T. and Javaheri, T. and Jayarajah, U.U. and Jayaram, S. and Jazayeri, S.B. and Jebai, R. and Jemal, B. and Jeong, W. and Jha, R.P. and Jindal, H.A. and John-Akinola, Y.O. and Jonas, J.B. and Joo, T. and Joseph, N. and Joukar, F. and Jozwiak, J.J. and Jürisson, M. and Kabir, A. and Kacimi, S.E.O. and Kadashetti, V. and Kahe, F. and Kakodkar, P.V. and Kalankesh, L.R. and Kalankesh, L.R. and Kalhor, R. and Kamal, V.K. and Kamangar, F. and Kamath, A. and Kanchan, T. and Kandaswamy, E. and Kandel, H. and Kang, H.J. and Kanno, G.G. and Kapoor, N. and Kar, S.S. and Karanth, S.D. and Karaye, I.M. and Karch, A. and Karimi, A. and Kassa, B.G. and Katoto, P.D.M.C. and Kauppila, J.H. and Kaur, H. and Kebede, A.G. and Keikavoosi-Arani, L. and Kejela, G.G. and Kemp Bohan, P.M. and Keramati, M. and Keykhaei, M. and Khajuria, H. and Khan, A. and Khan, A.A.K. and Khan, E.A. and Khan, G. and Khan, M.N. and Khan, M.A.B. and Khanali, J. and Khatab, K. and Khatatbeh, M.M. and Khatib, M.N. and Khayamzadeh, M. and Khayat Kashani, H.R. and Khazeei Tabari, M.A. and Khezeli, M. and Khodadost, M. and Kim, M.S. and Kim, Y.J. and Kisa, A. and Kisa, S. and Klugar, M. and Klugarová, J. and Kolahi, A.A. and Kolkhir, P. and Kompani, F. and Koul, P.A. and Koulmane Laxminarayana, S.L. and Koyanagi, A. and Krishan, K. and Krishnamoorthy, Y. and Kucuk Bicer, B. and Kugbey, N. and Kulimbet, M. and Kumar, A. and Kumar, G.A. and Kumar, N. and Kurmi, O.P. and Kuttikkattu, A. and La Vecchia, C. and Lahiri, A. and Lal, D.K. and Lám, J. and Lan, Q. and Landires, I. and Larijani, B. and Lasrado, S. and Lau, J. and Lauriola, P. and Ledda, C. and Lee, S.W. and Lee, S.W.H. and Lee, W.C. and Lee, Y.Y. and Lee, Y.H. and Legesse, S.M. and Leigh, J. and Leong, E. and Li, M.C. and Lim, S.S. and Liu, G. and Liu, J. and Lo, C.H. and Lohiya, A. and Lopukhov, P.D. and Lorenzovici, L. and Lotfi, M. and Loureiro, J.A. and Lunevicius, R. and Madadizadeh, F. and Mafi, A.R. and Magdeldin, S. and Mahjoub, S. and Mahmoodpoor, A. and Mahmoudi, M. and Mahmoudimanesh, M. and Mahumud, R.A. and Majeed, A. and Majidpoor, J. and Makki, A. and Makris, K.C. and Malakan Rad, E. and Malekpour, M.R. and Malekzadeh, R. and Malik, A.A. and Mallhi, T.H. and Mallya, S.D. and Mamun, M.A. and Manda, A.L. and Mansour-Ghanaei, F. and Mansouri, B. and Mansournia, M.A. and Mantovani, L.G. and Martini, S. and Martorell, M. and Masoudi, S. and Masoumi, S.Z. and Matei, C.N. and Mathews, E. and Mathur, M.R. and Mathur, V. and McKee, M. and Meena, J.K. and Mehmood, K. and Mehrabi Nasab, E. and Mehrotra, R. and Melese, A. and Mendoza, W. and Menezes, R.G. and Mengesha, S.D. and Mensah, L.G. and Mentis, A.F.A. and Mera-Mamián, A.Y.M. and Meretoja, T.J. and Merid, M.W. and Mersha, A.G. and Meselu, B.T. and Meshkat, M. and Mestrovic, T. and Miao Jonasson, J. and Miazgowski, T. and Michalek, I.M. and Mijena, G.F.W. and Miller, T.R. and Mir, S.A. and Mirinezhad, S.K. and Mirmoeeni, S. and Mirza-Aghazadeh-Attari, M. and Mirzaei, H. and Mirzaei, H.R. and Misganaw, A.S. and Misra, S. and Mohammad, K.A. and Mohammadi, E. and Mohammadi, M. and Mohammadian-Hafshejani, A. and Mohammadpourhodki, R. and Mohammed, A. and Mohammed, S. and Mohan, S. and Mohseni, M. and Moka, N. and Mokdad, A.H. and Molassiotis, A. and Molokhia, M. and Momenzadeh, K. and Momtazmanesh, S. and Monasta, L. and Mons, U. and Montasir, A.A. and Montazeri, F. and Montero, A. and Moosavi, M.A. and Moradi, A. and Moradi, Y. and Moradi Sarabi, M. and Moraga, P. and Morawska, L. and Morrison, S.D. and Morze, J. and Mosapour, A. and Mostafavi, E. and Mousavi, S.M. and Mousavi Isfahani, H. and Mousavi Khaneghah, A. and Mpundu-Kaambwa, C. and Mubarik, S. and Mulita, F. and Munblit, D. and Munro, S.B. and Murillo-Zamora, E. and Musa, J. and Nabhan, A.F. and Nagarajan, A.J. and Nagaraju, S.P. and Nagel, G. and Naghipour, M. and Naimzada, M.D. and Nair, T.S. and Naqvi, A.A. and Narasimha Swamy, S. and Narayana, A.I. and Nassereldine, H. and Natto, Z.S. and Nayak, B.P. and Ndejjo, R. and Nduaguba, S.O. and Negash, W.W. and Nejadghaderi, S.A. and Nejati, K. and Neupane Kandel, S. and Nguyen, H.V.N. and Niazi, R.K. and Noor, N.M. and Noori, M. and Noroozi, N. and Nouraei, H. and Nowroozi, A. and Nuñez-Samudio, V. and Nzoputam, C.I. and Nzoputam, O.J. and Oancea, B. and Odukoya, O.O. and Oghenetega, O.B. and Ogunsakin, R.E. and Oguntade, A.S. and Oh, I.H. and Okati-Aliabad, H. and Okekunle, A.P. and Olagunju, A.T. and Olagunju, T.O. and Olakunde, B.O. and Olufadewa, I.L. and Omer, E. and Omonisi, A.E.E. and Ong, S. and Onwujekwe, O.E. and Orru, H. and Otstavnov, S.S. and Oulhaj, A. and Oumer, B. and Owopetu, O.F. and Oyinloye, B.E. and P A, M. and Padron-Monedero, A. and Padubidri, J. and Pakbin, B. and Pakshir, K. and Pakzad, R. and Palicz, T. and Pana, A. and Pandey, A. and Pandey, A. and Pant, S. and Pardhan, S. and Park, E.C. and Park, E.K. and Park, S. and Patel, J. and Pati, S. and Paudel, R. and Paudel, U. and Paun, M. and Pazoki Toroudi, H. and Peng, M. and Pereira, J. and Pereira, R.B. and Perna, S. and Perumalsamy, N. and Pestell, R.G. and Pezzani, R. and Piccinelli, C. and Pillay, J.D. and Piracha, Z.Z. and Pischon, T. and Postma, M.J. and Pourabhari Langroudi, A. and Pourshams, A. and Pourtaheri, N. and Prashant, A. and Qadir, M.M.F. and Quazi Syed, Z. and Rabiee, M. and Rabiee, N. and Radfar, A. and Radhakrishnan, R.A. and Radhakrishnan, V. and Raeisi, M. and Rafiee, A. and Rafiei, A. and Raheem, N. and Rahim, F. and Rahman, M.O. and Rahman, M. and Rahman, M.A. and Rahmani, A.M. and Rahmani, S. and Rahmanian, V. and Rajai, N. and Rajesh, A. and Ram, P. and Ramezanzadeh, K. and Rana, J. and Ranabhat, K. and Ranasinghe, P. and Rao, C.R. and Rao, S.J. and Rashedi, S. and Rashidi, A. and Rashidi, M. and Rashidi, M.M. and Ratan, Z.A. and Rawaf, D.L. and Rawaf, S. and Rawal, L. and Rawassizadeh, R. and Razeghinia, M.S. and Rehman, A.U. and Rehman, I.U. and Reitsma, M.B and Renzaho, A.M.N. and Rezaei, M. and Rezaei, N. and Rezaei, N. and Rezaei, N. and Rezaei, S. and Rezaeian, M. and Rezapour, A. and Riad, A. and Rikhtegar, R. and Rios-Blancas, M. and Roberts, T.J. and Rohloff, P. and Romero-Rodríguez, E. and Roshandel, G. and Rwegerera, G.M. and S, M. and Saber-Ayad, M.M. and Saberzadeh-Ardestani, B. and Sabour, S. and Saddik, B. and Sadeghi, E. and Saeb, M.R. and Saeed, U. and Safaei, M. and Safary, A. and Sahebazzamani, M. and Sahebkar, A. and Sahoo, H. and Sajid, M.R. and Salari, H. and Salehi, S. and Salem, M.R. and Salimzadeh, H. and Samodra, Y.L. and Samy, A.M. and Sanabria, J. and Sankararaman, S. and Sanmarchi, F. and Santric-Milicevic, M.M. and Saqib, M.A.N. and Sarveazad, A. and Sarvi, F. and Sathian, B. and Satpathy, M. and Sayegh, N. and Schneider, I.J.C. and Schwarzinger, M. and Šekerija, M. and Senthilkumaran, S. and Sepanlou, S.G. and Seylani, A. and Seyoum, K. and Sha, F. and Shafaat, O. and Shah, P.A. and Shahabi, S. and Shahid, I. and Shahrbaf, M.A. and Shahsavari, H.R. and Shaikh, M.A. and Shaka, M.F. and Shaker, E. and Shannawaz, M. and Sharew, M.M.S. and Sharifi, A. and Sharifi-Rad, J. and Sharma, P. and Shashamo, B.B. and Sheikh, A. and Sheikh, M. and Sheikhbahaei, S. and Sheikhi, R.A. and Sheikhy, A. and Shepherd, P.R. and Shetty, A. and Shetty, J.K. and Shetty, R.S. and Shibuya, K. and Shirkoohi, R. and Shirzad-Aski, H. and Shivakumar, K.M. and Shivalli, S. and Shivarov, V. and Shobeiri, P. and Shokri Varniab, Z. and Shorofi, S.A. and Shrestha, S. and Sibhat, M.M. and Siddappa Malleshappa, S.K. and Sidemo, N.B. and Silva, D.A.S. and Silva, L.M.L.R. and Silva Julian, G. and Silvestris, N. and Simegn, W. and Singh, A.D. and Singh, A. and Singh, G. and Singh, H. and Singh, J.A. and Singh, J.K. and Singh, P. and Singh, S. and Sinha, D.N. and Sinke, A.H. and Siraj, M.S. and Sitas, F. and Siwal, S.S. and Skryabin, V.Y. and Skryabina, A. A. and Socea, B. and Soeberg, M.J. and Sofi-Mahmudi, A. and Solomon, Y. and Soltani-Zangbar, M.S. and Song, S. and Song, Y. and Sorensen, R.J.D. and Soshnikov, S. and Sotoudeh, H. and Sowe, A. and Sufiyan, M.B. and Suk, R. and Suleman, M. and Suliankatchi Abdulkader, R. and Sultana, S. and Sur, D. and Szócska, M. and Tabaeian, S.P. and Tabarés-Seisdedos, R. and Tabatabaei, S.M. and Tabuchi, T. and Tadbiri, H. and Taheri, E. and Taheri, M. and Taheri Soodejani, M. and Takahashi, K. and Talaat, I.M. and Tampa, M. and Tan, K.K. and Tat, N.Y. and Tat, V.Y. and Tavakoli, A. and Tavakoli, A. and Tehrani-Banihashemi, A. and Tekalegn, Y. and Tesfay, F.H. and Thapar, R. and Thavamani, A. and Thoguluva Chandrasekar, V. and Thomas, N. and Thomas, N.K. and Ticoalu, J.H.V. and Tiyuri, A. and Tollosa, D.N. and Topor-Madry, R. and Touvier, M. and Tovani-Palone, M.R. and Traini, E. and Tran, M.T.N. and Tripathy, J.P. and Ukke, G.G. and Ullah, I. and Ullah, S. and Ullah, S. and Unnikrishnan, B. and Vacante, M. and Vaezi, M. and Valadan Tahbaz, S. and Valdez, P.R. and Vardavas, C. and Varthya, S.B. and Vaziri, S. and Velazquez, D.Z. and Veroux, M. and Villeneuve, P.J. and Violante, F.S. and Vladimirov, S.K. and Vlassov, V. and Vo, B. and Vu, L.G. and Wadood, A.W. and Waheed, Y. and Walde, M.T. and Wamai, R.G. and Wang, C. and Wang, F. and Wang, N. and Wang, Y. and Ward, P. and Waris, A. and Westerman, R. and Wickramasinghe, N.D. and Woldemariam, M. and Woldu, B. and Xiao, H. and Xu, S. and Xu, X. and Yadav, L. and Yahyazadeh Jabbari, S.H. and Yang, L. and Yazdanpanah, F. and Yeshaw, Y. and Yismaw, Y. and Yonemoto, N. and Younis, M.Z. and Yousefi, Z. and Yousefian, F. and Yu, C. and Yu, Y. and Yunusa, I. and Zahir, M. and Zaki, N. and Zaman, B.A. and Zangiabadian, M. and Zare, F. and Zare, I. and Zareshahrabadi, Z. and Zarrintan, A. and Zastrozhin, M.S. and Zeineddine, M.A. and Zhang, D. and Zhang, J. and Zhang, Y. and Zhang, Z.J. and Zhou, L. and Zodpey, S. and Zoladl, M. and Vos, T. and Hay, S.I. and Force, L.M. and Murray, C.J.L.
Lancet 400 (10352): 563-591. 20 August 2022

Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.
Zhai, Y. and Singh, P. and Dolnik, A. and Brazda, P. and Atlasy, N. and Del Gaudio, N. and Döhner, K. and Döhner, H. and Minucci, S. and Martens, J. and Altucci, L. and Megchelenbrink, W. and Bullinger, L. and Stunnenberg, H.G.
Molecular Cancer 21 (1): 166. 19 August 2022

Functional modulation of PTH1R activation and signaling by RAMP2.
Nemec, K. and Schihada, H. and Kleinau, G. and Zabel, U. and Grushevsky, E.O. and Scheerer, P. and Lohse, M.J. and Maiellaro, I.
Proceedings of the National Academy of Sciences of the United States of America 119 (32): e2122037119. 9 August 2022

Reduced splenic uptake on (68)Ga-Pentixafor-PET/CT imaging in multiple myeloma - a potential imaging biomarker for disease prognosis.
Kraus, S. and Klassen, P. and Kircher, M. and Dierks, A. and Habringer, S. and Gäble, A. and Kortüm, K.M. and Weinhold, N. and Ademaj-Kospiri, V. and Werner, R.A. and Schirbel, A. and Buck, A.K. and Herhaus, P. and Wester, H.J. and Rosenwald, A. and Weber, W.A. and Einsele, H. and Keller, U. and Rasche, L. and Lapa, C.
Theranostics 12 (13): 5986-5994. 8 August 2022

Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi, Y. and Arango-Ossa, J.E. and Zhou, Y. and Bernard, E. and Thomas, I. and Gilkes, A. and Freeman, S. and Pradat, Y. and Johnson, S.J. and Hills, R. and Dillon, R. and Levine, M.F. and Leongamornlert, D. and Butler, A. and Ganser, A. and Bullinger, L. and Döhner, K. and Ottmann, O. and Adams, R. and Döhner, H. and Campbell, P.J. and Burnett, A.K. and Dennis, M. and Russell, N.H. and Devlin, S.M. and Huntly, B.J.P. and Papaemmanuil, E.
Nature Communications 13 (1): 4622. 8 August 2022

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies.
Reichart, D. and Lindberg, E.L. and Maatz, H. and Miranda, A.M.A. and Viveiros, A. and Shvetsov, N. and Gärtner, A. and Nadelmann, E.R. and Lee, M. and Kanemaru, K. and Ruiz-Orera, J. and Strohmenger, V. and DeLaughter, D.M. and Patone, G. and Zhang, H. and Woehler, A. and Lippert, C. and Kim, Y. and Adami, E. and Gorham, J.M. and Barnett, S.N. and Brown, K. and Buchan, R.J. and Chowdhury, R.A. and Constantinou, C. and Cranley, J. and Felkin, L.E. and Fox, H. and Ghauri, A. and Gummert, J. and Kanda, M. and Li, R. and Mach, L. and McDonough, B. and Samari, S. and Shahriaran, F. and Yapp, C. and Stanasiuk, C. and Theotokis, P.I. and Theis, F.J. and van den Bogaerdt, A. and Wakimoto, H. and Ware, J.S. and Worth, C.L. and Barton, P.J.R. and Lee, Y.A. and Teichmann, S.A. and Milting, H. and Noseda, M. and Oudit, G.Y. and Heinig, M. and Seidman, J.G. and Hubner, N. and Seidman, C.E.
Science 377 (6606): eabo1984. 5 August 2022

Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice.
Schepanski, S. and Chini, M. and Sternemann, V. and Urbschat, C. and Thiele, K. and Sun, T. and Zhao, Y. and Poburski, M. and Woestemeier, A. and Thieme, M.T. and Zazara, D.E. and Alawi, M. and Fischer, N. and Heeren, J. and Vladimirov, N. and Woehler, A. and Puelles, V.G. and Bonn, S. and Gagliani, N. and Hanganu-Opatz, I.L. and Arck, P.C.
Nature Communications 13 (1): 4571. 5 August 2022

Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska, R. and Mikecin, A.M. and Kaschutnig, P. and Fawaz, M. and Büchler-Schäff, M. and Le, D. and Ganuza, M. and Vollmer, A. and Paffenholz, S.V. and Asada, N. and Rodriguez-Correa, E. and Frauhammer, F. and Buettner, F. and Ball, M. and Knoch, J. and Stäble, S. and Walter, D. and Petri, A. and Carreño-Gonzalez, M.J. and Wagner, V. and Brors, B. and Haas, S. and Lipka, D.B. and Essers, M.A.G. and Weru, V. and Holland-Letz, T. and Mallm, J.P. and Rippe, K. and Krämer, S. and Schlesner, M. and McKinney Freeman, S. and Florian, M.C. and King, K.Y. and Frenette, P.S. and Rieger, M.A. and Milsom, M.D.
Cell Stem Cell 29 (8): 1273-1284. 4 August 2022

A high-resolution map of human RNA translation.
Chothani, S.P. and Adami, E. and Widjaja, A.A. and Langley, S.R. and Viswanathan, S. and Pua, C.J. and Zhihao, N.T. and Harmston, N. and D'Agostino, G. and Whiffin, N. and Mao, W. and Ouyang, J.F. and Lim, W.W. and Lim, S. and Lee, C.Q.E. and Grubman, A. and Chen, J. and Kovalik, J.P. and Tryggvason, K. and Polo, J.M. and Ho, L. and Cook, S.A. and Rackham, O.J.L. and Schafer, S.
Molecular Cell 82 (15): 2885-2899.e8. 4 August 2022

Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M. and Wang, Y.H. and Kaufmann, U. and Gerbeth, L. and Sand, A. and Brunkhorst, M. and Weidner, P. and Ziegler, J.F. and Böttcher, C. and Schlickeiser, S. and Fernández, C. and Yamashita, M. and Stauderman, K. and Sun, K. and Kunkel, D. and Prakriya, M. and Sanders, A.D. and Siegmund, B. and Feske, S. and Weidinger, C.
EMBO Molecular Medicine : e15687. 2 August 2022

The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S. and Cabantog, A. and MacPhee, L. and Im, J. and Ruess, C. and Demir, B. and Sperb, N. and Rücker, F.G. and Döhner, K. and Herold, T. and Pollack, J.R. and Bullinger, L. and Rouhi, A. and Kuchenbauer, F.
Haematologica 107 (8): 1758-1772. August 2022

Origin and function of activated fibroblast states during zebrafish heart regeneration.
Hu, B. and Lelek, S. and Spanjaard, B. and El-Sammak, H. and Simões, M.G. and Mintcheva, J. and Aliee, H. and Schäfer, R. and Meyer, A.M. and Theis, F. and Stainier, D.Y.R. and Panáková, D. and Junker, J.P.
Nature Genetics 54 (8): 1227-1237. August 2022

Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow, J. and Gross, S. and Busack, L. and Flörcken, A. and Jesse, J. and Schwarz, M. and Neuendorff, N.R. and von Brünneck, A.C. and Anagnostopoulos, I. and Türkmen, S. and Blau, I.W. and Burmeister, T. and Horst, D. and Bullinger, L. and Westermann, J.
Haematologica 107 (8): 1773-1785. August 2022

Transient activated fibroblasts contribute to zebrafish heart regeneration.
Junker, J.P. and Panáková, D.
Nature Genetics 54 (8): 1076-1077. August 2022

A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts.
Jäger, K. and Mensch, J. and Grimmig, M.E. and Neuner, B. and Gorzelniak, K. and Türkmen, S. and Demuth, I. and Hartmann, A. and Hartmann, C. and Wittig, F. and Sporbert, A. and Hermann, A. and Fuellen, G. and Möller, S. and Walter, M.
Science Advances 8 (33): eabk2814. August 2022

Renal deletion of LRRC8/VRAC channels induces proximal tubulopathy.
López-Cayuqueo, K.I. and Planells-Cases, R. and Pietzke, M. and Oliveras, A. and Kempa, S. and Bachmann, S. and Jentsch, T.J.
Journal of the American Society of Nephrology 33 (8): 1528-1545. August 2022

Deep Visual Proteomics defines single-cell identity and heterogeneity.
Mund, A. and Coscia, F. and Kriston, A. and Hollandi, R. and Kovács, F. and Brunner, A.D. and Migh, E. and Schweizer, L. and Santos, A. and Bzorek, M. and Naimy, S. and Rahbek-Gjerdrum, L.M. and Dyring-Andersen, B. and Bulkescher, J. and Lukas, C. and Eckert, M.A. and Lengyel, E. and Gnann, C. and Lundberg, E. and Horvath, P. and Mann, M.
Nature Biotechnology 40 (8): 1231-1240. August 2022

Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells.
Pardo, M. and Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Schneider, E. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Karg, E. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Shalit, T. and Gröger, T. and Rüger, C.P. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Zimmermann, R. and Rudich, Y.
Environment International 166 : 107366. August 2022

Optogenetics at the presynapse.
Rost, B.R. and Wietek, J. and Yizhar, O. and Schmitz, D.
Nature Neuroscience 25 (8): 984-998. August 2022

CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Rousselle, A. and Sonnemann, J. and Amann, K. and Mildner, A. and Lodka, D. and Kling, L. and Bieringer, M. and Schneider, U. and Leutz, A. and Enghard, P. and Kettritz, R. and Schreiber, A.
Annals of the Rheumatic Diseases 81 (8): 1162-1172. August 2022

B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
Schmid, V.K. and Khadour, A. and Ahmed, N. and Brandl, C. and Nitschke, L. and Rajewsky, K. and Jumaa, H. and Hobeika, E.
Haematologica 107 (8): 1796-1814. August 2022

The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells.
Viñado, A.C. and Calvo, I.A. and Cenzano, I. and Olaverri, D. and Cocera, M. and San Martin-Uriz, P. and Romero, J.P. and Vilas-Zornoza, A. and Vera, L. and Gomez-Cebrian, N. and Puchades-Carrasco, L. and Lisi-Vega, L.E. and Apaolaza, I. and Valera, P. and Guruceaga, E. and Granero-Molto, F. and Ripalda-Cemborain, P. and Luck, T.J. and Bullinger, L. and Planes, F.J. and Rifon, J.J. and Méndez-Ferrer, S. and Yusuf, R.Z. and Pardo-Saganta, A. and Prosper, F. and Saez, B.
Leukemia 36 (8): 1969-1979. August 2022

Application of precision medicine in clinical routine in haematology - challenges and opportunities.
Wästerlid, T. and Cavelier, L. and Haferlach, C. and Konopleva, M. and Fröhling, S. and Östling, P. and Bullinger, L. and Fioretos, T. and Smedby, K.E.
Journal of Internal Medicine 292 (2): 243-261. August 2022

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H. and Pusch, F. and Bei, Y. and von Stebut, J. and Ibáñez, G. and Guillan, K. and Imami, K. and Gürgen, D. and Rolff, J. and Helmsauer, K. and Meyer-Liesener, S. and Timme, N. and Bardinet, V. and Chamorro González, R. and MacArthur, I.C. and Chen, C.Y. and Schulz, J. and Wengner, A.M. and Furth, C. and Lala, B. and Eggert, A. and Seifert, G. and Hundsoerfer, P. and Kirchner, M. and Mertins, P. and Selbach, M. and Lissat, A. and Dubois, F. and Horst, D. and Schulte, J.H. and Spuler, S. and You, D. and Dela Cruz, F. and Kung, A.L. and Haase, K. and Di Virgilio, M. and Scheer, M. and Ortiz, M.V. and Henssen, A.G.
Nature Communications 13 (1): 4297. 25 July 2022

Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding.
Conte, M. and Irani, E. and Chiariello, A.M. and Abraham, A. and Bianco, S. and Esposito, A. and Nicodemi, M.
Nature Communications 13 (1): 4070. 13 July 2022

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
Axelsson Raja, A. and Wakimoto, H. and DeLaughter, D.M. and Reichart, D. and Gorham, J. and Conner, D.A. and Lun, M. and Probst, C.K. and Sakai, N. and Knipe, R.S. and Montesi, S.B. and Shea, B. and Adam, L.P. and Leinwand, L.A. and Wan, W. and Choi, E.S. and Lindberg, E.L. and Patone, G. and Noseda, M. and Hübner, N. and Seidman, C.E. and Tager, A.M. and Seidman, J.G. and Ho, C.Y.
Proceedings of the National Academy of Sciences of the United States of America 119 (28): e2204174119. 12 July 2022

Temperature elevations can induce switches to homoclinic action potentials that alter neural encoding and synchronization.
Hesse, J. and Schleimer, J.H. and Maier, N. and Schmitz, D. and Schreiber, S.
Nature Communications 13 (1): 3934. 8 July 2022

Biosynthetic potential of the global ocean microbiome.
Paoli, L. and Ruscheweyh, H.J. and Forneris, C.C. and Hubrich, F. and Kautsar, S. and Bhushan, A. and Lotti, A. and Clayssen, Q. and Salazar, G. and Milanese, A. and Carlström, C.I. and Papadopoulou, C. and Gehrig, D. and Karasikov, M. and Mustafa, H. and Larralde, M. and Carroll, L.M. and Sánchez, P. and Zayed, A.A. and Cronin, D.R. and Acinas, S.G. and Bork, P. and Bowler, C. and Delmont, T.O. and Gasol, J.M. and Gossert, A.D. and Kahles, A. and Sullivan, M.B. and Wincker, P. and Zeller, G. and Robinson, S.L. and Piel, J. and Sunagawa, S.
Nature 607 (7917): 111-118. 7 July 2022

Impaired AMP-activated protein kinase signaling in heart failure with preserved ejection fraction-associated atrial fibrillation.
Tong, D. and Schiattarella, G.G. and Jiang, N. and Daou, D. and Luo, Y. and Link, M.S. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Circulation 146 (1): 73-76. 5 July 2022

Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.
Wizenty, J. and Müllerke, S. and Kolesnichenko, M. and Heuberger, J. and Lin, M. and Fischer, A.S. and Mollenkopf, H.J. and Berger, H. and Tacke, F. and Sigal, M.
EMBO Journal 41 (13): e109996. 4 July 2022

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C. and Acemel, R.D. and Jedamzick, J. and Bolondi, A. and Cova, G. and Brieske, N. and Kühn, R. and Wittler, L. and Real, F.M. and Lupiáñez, D.G.
Nature Genetics July 2022

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D. and Hörtenhuber, M. and Balwierz, P.J. and Zehnder, T. and Mukarram, A.K. and Nepal, C. and Várnai, C. and Hadzhiev, Y. and Jimenez-Gonzalez, A. and Li, N. and Wragg, J. and D'Orazio, F.M. and Relic, D. and Pachkov, M. and Díaz, N. and Hernández-Rodríguez, B. and Chen, Z. and Stoiber, M. and Dong, M. and Stevens, I. and Ross, S.E. and Eagle, A. and Martin, R. and Obasaju, O. and Rastegar, S. and McGarvey, A.C. and Kopp, W. and Chambers, E. and Wang, D. and Kim, H.R. and Acemel, R.D. and Naranjo, S. and Łapiński, M. and Chong, V. and Mathavan, S. and Peers, B. and Sauka-Spengler, T. and Vingron, M. and Carninci, P. and Ohler, U. and Lacadie, S.A. and Burgess, S.M. and Winata, C. and van Eeden, F. and Vaquerizas, J.M. and Gómez-Skarmeta, J.L. and Onichtchouk, D. and Brown, B.J. and Bogdanovic, O. and van Nimwegen, E. and Westerfield, M. and Wardle, F.C and Daub, C.O. and Lenhard, B. and Müller, F.
Nature Genetics 54 (7): 1037-1050. July 2022

Crosstalk between the renin-angiotensin, complement and kallikrein-kinin systems in inflammation.
Bekassy, Z. and Lopatko Fagerström, I. and Bader, M. and Karpman, D.
Nature Reviews Immunology 22 (7): 411-428. July 2022

Clonal hematopoiesis of indeterminate potential-related epigenetic age acceleration correlates with clonal hematopoiesis of indeterminate potential clone size in patients with high morbidity.
Feldkamp, J.D. and Vetter, V.M. and Arends, C.M. and Lang, T.J.L. and Bullinger, L. and Damm, F. and Demuth, I. and Frick, M.
Haematologica 107 (7): 1703-1708. July 2022

Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications.
Gawałko, M. and Agbaedeng, T.A. and Saljic, A. and Mueller, D.N. and Wilck, N. and Schnabel, R. and Penders, J. and Rienstra, M. and van Gelder, I. and Jespersen, T. and Schotten, U. and Crijns, H.J.G.M. and Kalman, J.M. and Sanders, P. and Nattel, S. and Dobrev, D. and Linz, D.
Cardiovascular Research 118 (11): 2415–2427. July 2022

Identification of early neurodegenerative pathways in progressive multiple sclerosis.
Kaufmann, M. and Schaupp, A.L. and Sun, R. and Coscia, F. and Dendrou, C.A. and Cortes, A. and Kaur, G. and Evans, H.G. and Mollbrink, A. and Navarro, J.F. and Sonner, J.K. and Mayer, C. and DeLuca, G.C. and Lundeberg, J. and Matthews, P.M. and Attfield, K.E. and Friese, M.A. and Mann, M. and Fugger, L.
Nature Neuroscience 25 (7): 944-955. July 2022

Standardized annotation of translated open reading frames.
Mudge, J.M. and Ruiz-Orera, J. and Prensner, J.R. and Brunet, M.A. and Calvet, F. and Jungreis, I. and Gonzalez, Jo.M. and Magrane, M. and Martinez, T.F. and Schulz, J.F. and Yang, Y.T. and Albà, M.M. and Aspden, J.L. and Baranov, P.V. and Bazzini, A.A. and Bruford, E. and Martin, M.J. and Calviello, L. and Carvunis, A.R. and Chen, J. and Couso, J.P. and Deutsch, E.W. and Flicek, P. and Frankish, A. and Gerstein, M. and Hubner, N. and Ingolia, N.T. and Kellis, M. and Menschaert, G. and Moritz, R.L. and Ohler, U. and Roucou, X. and Saghatelian, A. and Weissman, J.S. and van Heesch, S.
Nature Biotechnology 40 (7): 994–999. July 2022

Interneuron switching on and off across memory rhythms.
Tzilivaki, A. and Maier, N. and Schmitz, D.
Neuron 110 (12): 1884-1886. 15 June 2022

Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Berlak, M. and Tucker, E. and Dorel, M. and Winkler, A. and McGearey, A. and Rodriguez-Fos, E. and da Costa, B.M. and Barker, K. and Fyle, E. and Calton, E. and Eising, S. and Ober, K. and Hughes, D. and Koutroumanidou, E. and Carter, P. and Stankunaite, R. and Proszek, P. and Jain, N. and Rosswog, C. and Dorado-Garcia, H. and Molenaar, J.J. and Hubank, M. and Barone, G. and Anderson, J. and Lang, P. and Deubzer, H.E. and Künkele, A. and Fischer, M. and Eggert, A. and Kloft, C. and Henssen, A.G. and Boettcher, M. and Hertwig, F. and Blüthgen, N. and Chesler, L. and Schulte, J.H.
Molecular Cancer 21 (1): 126. 10 June 2022

IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis.
Garnier, L. and Pick, R. and Montorfani, J. and Sun, M. and Brighouse, D. and Liaudet, N. and Kammertoens, T. and Blankenstein, T. and Page, N. and Bernier-Latamani, J. and Tran, N.L. and Petrova, T.V. and Merkler, D. and Scheiermann, C. and Hugues, S.
Science Advances 8 (23): eabl5162. 8 June 2022

A faecal microbiota signature with high specificity for pancreatic cancer.
Kartal, E. and Schmidt, T.S.B. and Molina-Montes, E. and Rodríguez-Perales, S. and Wirbel, J. and Maistrenko, O.M. and Akanni, W.A. and Alashkar Alhamwe, B. and Alves, R.J. and Carrato, A. and Erasmus, H.P. and Estudillo, L. and Finkelmeier, F. and Fullam, A. and Glazek, A.M. and Gómez-Rubio, P. and Hercog, R. and Jung, F. and Kandels, S. and Kersting, S. and Langheinrich, M. and Márquez, M. and Molero, X. and Orakov, A. and Van Rossum, T. and Torres-Ruiz, R. and Telzerow, A. and Zych, K. and Benes, V. and Zeller, G. and Trebicka, J. and Real, F.X. and Malats, N. and Bork, P.
Gut 71 (7): 1359-1372. 7 June 2022

Mafa-dependent GABAergic activity promotes mouse neonatal apneas.
Lecoin, L. and Dempsey, B. and Garancher, A. and Bourane, S. and Ruffault, P.L. and Morin-Surun, M.P. and Rocques, N. and Goulding, M. and Eychène, A. and Pouponnot, C. and Fortin, G. and Champagnat, J.
Nature Communications 13 (1): 3284. 7 June 2022

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y. and Du Jiang, P. and Chao, B.N. and Cagdas, D. and Kubo, S. and Balasubramaniyam, A. and Zhang, Y. and Shadur, B. and NaserEddin, A. and Folio, L.R. and Schwarz, B. and Bohrnsen, E. and Zheng, L. and Lynberg, M. and Gottlieb, S. and Leney-Greene, M.A. and Park, A.Y. and Tezcan, I. and Akdogan, A. and Gocmen, R. and Onder, S. and Rosenberg, A. and Soilleux, E.J. and Johnson, E. and Jackson, P.K. and Demeter, J. and Chauvin, S.D. and Paul, F. and Selbach, M. and Bulut, H. and Clatworthy, M.R. and Tuong, Z.K. and Zhang, H. and Stewart, B.J. and Bosio, C.M. and Stepensky, P. and Clare, S. and Ganesan, S. and Pascall, J.C. and Daumke, O. and Butcher, G.W. and McMichael, A.J. and Simon, A.K. and Lenardo, M.J.
Journal of Experimental Medicine 219 (6): e20201405. 6 June 2022

Precise CRISPR/Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells.
Tran, N.T. and Danner, E. and Li, X. and Graf, R. and Lebedin, M. and de la Rosa, K. and Kühn, R. and Rajewsky, K. and Chu, V.T.
Science Advances 8 (22): eabm9106. 3 June 2022

Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H. and Dauksaite, V. and Sporbert, A. and Gotthardt, M. and Selbach, M.
Molecular Cell 82 (11): 2069-2083. 2 June 2022

Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.
Dzamukova, M. and Brunner, T.M. and Miotla-Zarebska, J. and Heinrich, F. and Brylka, L. and Mashreghi, M.F. and Kusumbe, A. and Kühn, R. and Schinke, T. and Vincent, T.L.. and Löhning, M.
Nature Communications 13 (1): 3059. 1 June 2022

Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19.
Dannebaum, R. and Suwalski, P. and Asgharian, H. and Du Zhipei, G. and Lin, H. and Weiner, J. and Holtgrewe, M. and Thibeault, C. and Müller, M. and Wang, X. and Karadeniz, Z. and Saccomanno, J. and Doehn, J.M. and Hübner, R.H. and Hinzmann, B. and Blüher, A. and Siemann, S. and Telman, D. and Suttorp, N. and Witzenrath, M. and Hippenstiel, S. and Skurk, C. and Poller, W. and Sander, L.E. and Beule, D. and Kurth, F. and Guettouche, T. and Landmesser, U. and Berka, J. and Luong, K. and Rubelt, F. and Heidecker, B.
EClinicalMedicine 48 : 101438. June 2022

A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth.
Ong, Y.T. and Andrade, J. and Armbruster, M. and Shi, C. and Castro, M. and Costa, A.S.H. and Sugino, T. and Eelen, G. and Zimmermann, B. and Wilhelm, K. and Lim, J. and Watanabe, S. and Guenther, S. and Schneider, A. and Zanconato, F. and Kaulich, M. and Pan, D. and Braun, T. and Gerhardt, H. and Efeyan, A. and Carmeliet, P. and Piccolo, S. and Grosso, A.R. and Potente, M.
Nature Metabolism 4 (6): 672-682. June 2022

A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Wu, Y. and Biswas, D. and Usaite, I. and Angelova, M. and Boeing, S. and Karasaki, T. and Veeriah, S. and Czyzewska-Khan, J. and Morton, C. and Joseph, M. and Hessey, S. and Reading, J. and Georgiou, A. and Al-Bakir, M. and McGranahan, N. and Jamal-Hanjani, M. and Hackshaw, A. and Quezada, S.A. and Hayday, A.C. and Swanton, C.
Nature Cancer 3 (6): 696-709. June 2022

Proton-gated anion transport governs macropinosome shrinkage.
Zeziulia, M. and Blin, S. and Schmitt, F.W. and Lehmann, M. and Jentsch, T.J.
Nature Cell Biology 24 (6): 885-895. June 2022

Identifying tumor cells at the single-cell level using machine learning.
Dohmen, J. and Baranovskii, A. and Ronen, J. and Uyar, B. and Franke, V. and Akalin, A.
Genome Biology 23 (1): 123. 30 May 2022

Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
Schmiester, M. and Maier, R. and Riedel, R. and Durek, P. and Frentsch, M. and Kolling, S. and Mashreghi, M.F. and Jenq, R. and Zhang, L. and Peterson, C.B. and Bullinger, L. and Chang, H.D. and Na, I.K.
Gut Microbes 14 (1): e2081475. 29 May 2022

Selective endocytosis of Ca(2+)-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.
Azarnia Tehran, D. and Kochlamazashvili, G. and Pampaloni, N. P. and Sposini, S. and Shergill, J.K. and Lehmann, M. and Pashkova, N. and Schmidt, C. and Löwe, D. and Napieczynska, H. and Heuser, A. and Plested, A.J.R. and Perrais, D. and Piper, R.C. and Haucke, V. and Maritzen, T.
Science Advances 8 (21): eabl5032. 27 May 2022

Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity.
Batlle, D. and Monteil, V. and Garreta, E. and Hassler, L. and Wysocki, J. and Chandar, V. and Schwartz, R.E. and Mirazimi, A. and Montserrat, N. and Bader, M. and Penninger, J.M.
Cell 185 (11): 1837-1839. 26 May 2022

Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders.
Porubsky, D. and Höps, W. and Ashraf, H. and Hsieh, P.H. and Rodriguez-Martin, B. and Yilmaz, F. and Ebler, J. and Hallast, P. and Maggiolini, F.A.M. and Harvey, W.T. and Henning, B. and Audano, P.A. and Gordon, D.S. and Ebert, P. and Hasenfeld, P. and Benito, E. and Zhu, Q. and Lee, C. and Antonacci, F. and Steinrücken, M. and Beck, C.R. and Sanders, A.D. and Marschall, T. and Eichler, E.E. and Korbel, J.O.
Cell 185 (11): 1986-2005. 26 May 2022

Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline: a randomized clinical tTrial.
Schwarz, C. and Benson, G.S. and Horn, N. and Wurdack, K. and Grittner, U. and Schilling, R. and Märschenz, S. and Köbe, T. and Hofer, S.J. and Magnes, C. and Stekovic, S. and Eisenberg, T. and Sigrist, S.J. and Schmitz, D. and Wirth, M. and Madeo, F. and Flöel, A.
JAMA Network Open 5 (5): e2213875. 26 May 2022

Serotonin limits generation of chromaffin cells during adrenal organ development.
Kameneva, P. and Melnikova, V.I. and Kastriti, M.E. and Kurtova, A. and Kryukov, E. and Murtazina, A. and Faure, L. and Poverennaya, I. and Artemov, A.V. and Kalinina, T.S. and Kudryashov, N.V. and Bader, M. and Skoda, J. and Chlapek, P. and Curylova, L. and Sourada, L. and Neradil, J. and Tesarova, M. and Pasqualetti, M. and Gaspar, P. and Yakushov, V.D. and Sheftel, B.I. and Zikmund, T. and Kaiser, J. and Fried, K. and Alenina, N. and Voronezhskaya, E.E. and Adameyko, I.
Nature Communications 13 (1): 2901. 25 May 2022

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U. and Milek, M. and Minia, I. and Vieira-Vieira, C.H. and Müller, S. and Mastrobuoni, G. and Hazapis, O.G. and Del Giudice, S. and Schwefel, D. and Bley, N. and Voigt, F. and Chao, J.A. and Kempa, S. and Hüttelmaier, S. and Selbach, M. and Landthaler, M.
Nature Communications 13 (1): 2727. 18 May 2022

Brain-wide interactions during hippocampal sharp wave ripples.
Nitzan, N. and Swanson, R. and Schmitz, D. and Buzsáki, G.
Proceedings of the National Academy of Sciences of the United States of America 119 (20): e2200931119. 17 May 2022

The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL.
Rejeski, K. and Perez, A. and Iacoboni, G. and Penack, O. and Bücklein, V. and Jentzsch, L. and Mougiakakos, D. and Johnson, G. and Arciola, B. and Carpio, C. and Blumenberg, V. and Hoster, E. and Bullinger, L. and Locke, F.L. and von Bergwelt-Baildon, M. and Mackensen, A. and Bethge, W. and Barba, P. and Jain, M.D. and Subklewe, M.
Journal for ImmunoTherapy of Cancer 10 (5): e004475. 17 May 2022

HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin, Y.H. and Major, J.L. and Liebner, T. and Hourani, Z. and Travers, J.G. and Wennersten, S.A. and Haefner, K.R. and Cavasin, M.A. and Wilson, C.E. and Jeong, M.Y. and Han, Y. and Gotthardt, M. and Ferguson, S.K. and Ambardekar, A.V. and Lam, M.P. and Choudhary, C. and Granzier, H.L. and Woulfe, K.C. and McKinsey, T.A.
Journal of Clinical Investigation 132 (10): e148333. 16 May 2022

The genomic and transcriptional landscape of primary central nervous system lymphoma.
Radke, J. and Ishaque, N. and Koll, R. and Gu, Z. and Schumann, E. and Sieverling, L. and Uhrig, S. and Hübschmann, D. and Toprak, U.H. and López, C. and Hostench, X.P. and Borgoni, S. and Juraeva, D. and Pritsch, F. and Paramasivam, N. and Balasubramanian, G.P. and Schlesner, M. and Sahay, S. and Weniger, M. and Pehl, D. and Radbruch, H. and Osterloh, A. and Korfel, A. and Misch, M. and Onken, J. and Faust, K. and Vajkoczy, P. and Moskopp, D. and Wang, Y. and Jödicke, A. and Trümper, L. and Anagnostopoulos, I. and Lenze, D. and Küppers, R. and Hummel, M. and Schmitt, C.A. and Wiestler, O.D. and Wolf, S. and Unterberg, A. and Eils, R. and Herold-Mende, C. and Brors, B. and Siebert, R. and Wiemann, S. and Heppner, F.L.
Nature Communications 13 (1): 2558. 10 May 2022

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca, P. and Vonficht, D. and Schnell, A. and Uckelmann, H.J. and Bollhagen, A. and Mahmoud, M.A.A. and Landua, S.L. and van der Salm, E. and Trautmann, C. and Raffel, S. and Grünschläger, F. and Lutz, R. and Ghosh, M. and Renders, S. and Correia, N. and Donato, E. and Dixon, K.O. and Hirche, C. and Andresen, C. and Robens, Cl. and Werner, P.S. and Boch, T. and Eisel, D. and Osen, W. and Pilz, F. and Przybylla, A. and Klein, C. and Buchholz, F. and Milsom, M.D. and Essers, M.A.G. and Eichmüller, S.B. and Hofmann, W.K. and Nowak, D. and Hübschmann, D. and Hundemer, M. and Thiede, C. and Bullinger, L. and Müller-Tidow, C. and Armstrong, S.A. and Trumpp, A. and Kuchroo, V.K. and Haas, S.
Cell Stem Cell 29 (5): 760-775. 5 May 2022

Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single cell transcriptomics.
Wyler, E. and Adler, J.M. and Eschke, K. and Teixeira Alves, G. and Peidli, S. and Pott, F. and Kazmierski, J. and Michalick, L. and Kershaw, O. and Bushe, J. and Andreotti, S. and Pennitz, P. and Abdelgawad, A. and Postmus, D. and Goffinet, C. and Kreye, J. and Reincke, S.M. and Prüss, H. and Blüthgen, N. and Gruber, A.D. and Kuebler, W.M. and Witzenrath, M. and Landthaler, M. and Nouailles, G. and Trimpert, J.
Molecular Therapy 30 (5): 1952-1965. 4 May 2022

The blood-brain barrier-a metabolic ecosystem.
Castro, M. and Potente, M.
EMBO Journal 41 (9): e111189. 2 May 2022

Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Demel, U.M. and Böger, M. and Yousefian, S. and Grunert, C. and Zhang, L. and Hotz, P.W. and Gottschlich, A. and Köse, H. and Isaakidis, K. and Vonficht, D. and Grünschläger, F. and Rohleder, E. and Wagner, K. and Dönig, J. and Igl, V. and Brzezicha, B. and Baumgartner, F. and Habringer, S. and Löber, J. and Chapuy, B. and Weidinger, C. and Kobold, S. and Haas, S. and Busse, A.B. and Müller, S. and Wirth, M. and Schick, M. and Keller, U.
Journal of Clinical Investigation 132 (9): e152383. 2 May 2022

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation.
Blassberg, R. and Patel, H. and Watson, T. and Gouti, M. and Metzis, V. and Delás, M.J. and Briscoe, J.
Nature Cell Biology 24 (5): 633-644. May 2022

Infectious complications of targeted drugs and biotherapies in acute leukemia. Clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL), a joint venture of the European Group for Blood and Marrow Transplantation (EBMT), the European Organization for Research and Treatment of Cancer (EORTC), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN).
Maschmeyer, G. and Bullinger, L. and Garcia-Vidal, C. and Herbrecht, R. and Maertens, J. and Menna, P. and Pagano, L. and Thiebaut-Bertrand, A. and Calandra, T.
Leukemia 36 (5): 1215-1226. May 2022

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H. and Flórez, A.F. and Kreth, S. and Brückner, L.M. and Yildiz, U. and Gartlgruber, M. and Odoni, D.I. and Poschet, G. and Garbowicz, K. and Shao, C. and Klein, C. and Meier, J. and Zeisberger, P. and Nadler-Holly, M. and Ziehm, M. and Paul, F. and Burhenne, J. and Bell, E. and Shaikhkarami, M. and Würth, R. and Stainczyk, S.A. and Wecht, E.M. and Kreth, J. and Büttner, M. and Ishaque, N. and Schlesner, M. and Nicke, B. and Stresemann, C. and Llamazares-Prada, M. and Reiling, J.H. and Fischer, M. and Amit, I. and Selbach, M. and Herrmann, C. and Wölfl, S. and Henrich, K.O. and Höfer, T. and Trumpp, A. and Westermann, F.
Nature Cancer 3 (4): 471-485. 28 April 2022

Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig, L.S. and Lareau, C.A. and Bao, E.L. and Liu, N. and Utsugisawa, T. and Tseng, A.M. and Myers, S.A. and Verboon, J.M. and Ulirsch, J.C. and Luo, W. and Muus, C. and Fiorini, C. and Olive, M.E. and Vockley, C.M. and Munschauer, M. and Hunter, A. and Ogura, H. and Yamamoto, T. and Inada, H. and Nakagawa, S. and Ozono, S. and Subramanian, V. and Chiarle, R. and Glader, B. and Carr, S.A. and Aryee, M.J. and Kundaje, A. and Orkin, S. and Regev, A. and McCavit, T. and Kanno, H. and Sankaran, V.G.
Blood 139 (16): 2534-2546. 21 April 2022

Cancer stem cells: The adventurous journey from hematopoietic to leukemic stem cells.
Trumpp, A. and Haas, S.
Cell 185 (8): 1266-1270. 14 April 2022

Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes.
Khedkar, S. and Smyshlyaev, G. and Letunic, I. and Maistrenko, O.M. and Coelho, L.P. and Orakov, A. and Forslund, S.K. and Hildebrand, F. and Luetge, M. and Schmidt, T.S.B. and Barabas, O. and Bork, P.
Nucleic Acids Research 50 (6): 3155-3168. 8 April 2022

Microcircuits for spatial coding in the medial entorhinal cortex.
Tukker, J.J. and Beed, P. and Brecht, M. and Kempter, R. and Moser, E.I. and Schmitz, D.
Physiological Reviews 102 (2): 653-688. 1 April 2022

Claudin-10a deficiency shifts proximal tubular Cl(-) permeability to cation selectivity via claudin-2 redistribution.
Breiderhoff, T. and Himmerkus, N. and Meoli, L. and Fromm, A. and Sewerin, S. and Kriuchkova, N. and Nagel, O. and Ladilov, Y. and Krug, S. and Quintanova, C. and Stumpp, M. and Garbe-Schönberg, D. and Westernströer, U. and Merkel, C. and Brinkhus, M. and Altmüller, J. and Schweiger, M. and Mueller, D. and Mutig, K. and Morawski, M. and Halbritter, J. and Milatz, S. and Bleich, M. and Günzel, D.
Journal of the American Society of Nephrology 33 (4): 699-717. April 2022

Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F. and Hablesreiter, R. and Hoyer, K. and Hennch, C. and Maluck-Böttcher, A. and Segler, A. and Madadi, A. and Frick, M. and Bullinger, L. and Briest, F. and Damm, F.
Leukemia 36 (4): 1102-1110. April 2022

Statistical analysis in the German National Cohort (NAKO) - specific aspects and general recommendations.
Kuss, O. and Becher, H. and Wienke, A. and Ittermann, T. and Ostrzinski, S. and Schipf, S. and Schmidt, C.O. and Leitzmann, M. and Pischon, T. and Krist, L. and Roll, S. and Sand, M. and Pohlabeln, H. and Rach, S. and Jöckel, K.H. and Stang, A. and Mueller, U.A. and Werdecker, A. and Westerman, R. and Greiser, K.H. and Michels, K.B.
European Journal of Epidemiology 37 (4): 429-436. April 2022

Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D. and Oshima, M. and Stange, D.E. and Sigal, M.
Gastroenterology 162 (4): 1067-1087. April 2022

A neutralizing IL-11 antibody improves renal function and increases lifespan in a mouse model of alport syndrome.
Widjaja, A.A. and Shekeran, S. and Adami, E. and Goh, J. and Tan, J. and Viswanathan, S. and Lim, S.Y. and Tan, P.H. and Hübner, N. and Coffman, T. and Cook, S.
Journal of the American Society of Nephrology 33 (4): 718-730. April 2022

Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling.
Anton, S.E. and Kayser, C. and Maiellaro, I. and Nemec, K. and Möller, J. and Koschinski, A. and Zaccolo, M. and Annibale, P. and Falcke, M. and Lohse, M.J. and Bock, A.
Cell 185 (7): 1130-1142.e11. 31 March 2022

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M. and Lin, M. and Maertzdorf, J. and Heuberger, J. and Muellerke, S. and Zuo, X. and Vidal, R. and Shureiqi, I. and Fischer, A.S. and Sauer, S. and Berger, H. and Kidess, E. and Mollenkopf, H.J. and Tacke, F. and Meyer, T.F. and Sigal, M.
Nature Communications 13 (1): 1577. 24 March 2022

Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection clusters based on integrated genomic surveillance, outbreak analysis and contact tracing in an urban setting.
Walker, A. and Houwaart, T. and Finzer, P. and Ehlkes, L. and Tyshaieva, A. and Damagnez, M. and Strelow, D. and Duplessis, A. and Nicolai, J. and Wienemann, T. and Tamayo, T. and Kohns Vasconcelos, M. and Hülse, L. and Hoffmann, K. and Lübke, N. and Hauka, S. and Andree, M. and Däumer, M.P. and Thielen, A. and Kolbe-Busch, S. and Göbels, K. and Zotz, R. and Pfeffer, K. and Timm, J. and Dilthey, A.T.
Clinical Infectious Diseases 74 (6): 1039-1046. 15 March 2022

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel, G. and Conlon, T.M. and Jeridi, A. and Kim, R. and Ertüz, Z. and Lang, N.J. and Ansari, M. and Novikova, M. and Jiang, D. and Strunz, M. and Gaianova, M. and Hollauer, C. and Gabriel, C. and Angelidis, I. and Doll, S. and Pestoni, J.C. and Edelmann, S.L. and Kohlhepp, M.S. and Guillot, A. and Bassler, K. and Van Eeckhoutte, H.P. and Kayalar, Ö. and Konyalilar, N. and Kanashova, T. and Rodius, S. and Ballester-López, C. and Genes Robles, C.M. and Smirnova, N. and Rehberg, M. and Agarwal, C. and Krikki, I. and Piavaux, B. and Verleden, S.E. and Vanaudenaerde, B. and Königshoff, M. and Dittmar, G. and Bracke, K.R. and Schultze, J.L. and Watz, H. and Eickelberg, O. and Stoeger, T. and Burgstaller, G. and Tacke, F. and Heissmeyer, V. and Rinkevich, Y. and Bayram, H. and Schiller, H.B. and Conrad, M. and Schneider, R. and Yildirim, A.Ö.
Nature Communications 13 (1): 1303. 14 March 2022

Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M. and Dimitriou, S. and Stahler, A. and Hablesreiter, R. and Strzelecka, P.M. and Stein, C.M. and Tilgner, M. and Saiki, R. and Ogawa, S. and Bullinger, L. and Modest, D.P. and Stintzing, S. and Heinemann, V. and Damm, F.
Blood 139 (10): 1593-1597. 10 March 2022

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
Cabral-Marques, O. and Halpert, G. and Schimke, L.F. and Ostrinski, Y. and Vojdani, A. and Baiocchi, G.C. and Freire, P.P. and Filgueiras, I.S. and Zyskind, I. and Lattin, M.T. and Tran, F. and Schreiber, S. and Marques, A.H.C. and Plaça, D.R. and Fonseca, D.L.M. and Humrich, J.Y. and Müller, A. and Giil, L.M. and Graßhoff, H. and Schumann, A. and Hackel, A. and Junker, J. and Meyer, C. and Ochs, H.D. and Lavi, Y.B. and Scheibenbogen, C. and Dechend, R. and Jurisica, I. and Schulze-Forster, K. and Silverberg, J.I. and Amital, H. and Zimmerman, J. and Heidecke, H. and Rosenberg, A.Z. and Riemekasten, G. and Shoenfeld, Y.
Nature Communications 13 (1): 1220. 9 March 2022

Fly Cell Atlas: a single-nucleus transcriptomic atlas of the adult fruit fly.
Li, H. and Janssens, J. and De Waegeneer, M. and Kolluru, S.S. and Davie, K. and Gardeux, V. and Saelens, W. and David, F.P.A. and Brbić, M. and Spanier, K. and Leskovec, J. and McLaughlin, C.N. and Xie, Q. and Jones, R.C. and Brueckner, K. and Shim, J. and Tattikota, S.G. and Schnorrer, F. and Rust, K. and Nystul, T.G. and Carvalho-Santos, Zi. and Ribeiro, C. and Pal, S. and Mahadevaraju, S. and Przytycka, T.M. and Allen, A.M. and Goodwin, S.F. and Berry, C.W. and Fuller, M.T. and White-Cooper, H. and Matunis, E.L. and DiNardo, S. and Galenza, A. and O'Brien, L.E. and Dow, J.A.T. and Jasper, H. and Oliver, B. and Perrimon, N. and Deplancke, B. and Quake, S.R. and Luo, L. and Aerts, S.
Science 375 (6584): eabk2432. 4 March 2022

Adolescence is a sensitive period for prefrontal microglia to act on cognitive development.
Schalbetter, S.M. and von Arx, A.S. and Cruz-Ochoa, N. and Dawson, K. and Ivanov, A. and Mueller, F.S. and Lin, H.Y. and Amport, R. and Mildenberger, W. and Mattei, D. and Beule, D. and Földy, C. and Greter, M. and Notter, T. and Meyer, U.
Science Advances 8 (9): eabi6672. 4 March 2022

Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells.
Yang, M. and Yu, H. and Yu, X. and Liang, S. and Hu, Y. and Luo, Y. and Izsvák, Z. and Sun, C. and Wang, J.
Cell Stem Cell 29 (3): 400-418.e13. 3 March 2022

NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
Doffo, J. and Bamopoulos, S.A. and Köse, H. and Orben, F. and Zang, C. and Pons, M. and den Dekker, A.T. and Brouwer, R.W.W. and Baluapuri, A. and Habringer, S. and Reichert, M. and Illendula, A. and Krämer, O.H. and Schick, M. and Wolf, E. and van IJcken, W.F.J. and Esposito, I. and Keller, U. and Schneider, G. and Wirth, M.
Proceedings of the National Academy of Sciences of the United States of America 119 (9): e2105691119. 1 March 2022

Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC.
Fiskin, E. and Lareau, C.A. and Ludwig, L.S. and Eraslan, G. and Liu, F. and Ring, A.M. and Xavier, R.J. and Regev, A.
Nature Biotechnology 40 (3): 374-381. March 2022

Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo, W.T. and Zhang, Y. and Vadas, O. and Roske, Y. and Gulluni, F. and De Santis, M.C. and Zagar, A.V. and Stephanowitz, H. and Hirsch, E. and Liu, F. and Daumke, O. and Kudryashev, M. and Haucke, V.
Nature Structural & Molecular Biology 29 (3): 218-228. March 2022

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić, S. and Prada-Medina, C.A. and Landoulsi, Z. and Ghelfi, J. and Delcambre, S. and Dietrich, C. and Jarazo, J. and Henck, J. and Balachandran, S. and Pachchek, S. and Morris, C.M. and Antony, P. and Timmermann, B. and Sauer, S. and Pereira, S.L. and Schwamborn, J.C. and May, P. and Grünewald, A. and Spielmann, M.
Brain 145 (3): 964-978. March 2022

Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
Subramanian, S. and Busch, C.J.L. and Molawi, K. and Geirsdottir, L. and Maurizio, J. and Vargas Aguilar, S. and Belahbib, H. and Gimenez, G. and Yuda, R.A.A. and Burkon, M. and Favret, J. and Gholamhosseinian Najjar, S. and de Laval, B. and Kandalla, P.K. and Sarrazin, S. and Alexopoulou, L. and Sieweke, M.H.
Nature Immunology 23 (3): 458-468. March 2022

A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants.
Shahan, R. and Hsu, C.W. and Nolan, T.M. and Cole, B.J. and Taylor, I.W. and Greenstreet, L. and Zhang, S. and Afanassiev, A. and Vlot, A.H.C. and Schiebinger, G. and Benfey, P.N. and Ohler, U.
Developmental Cell 57 (4): 543-560. 28 February 2022

Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations.
Miller, T.E. and Lareau, C.A. and Verga, J.A. and DePasquale, E.A.K. and Liu, V. and Ssozi, D. and Sandor, K. and Yin, Y. and Ludwig, L.S. and El Farran, C.A. and Morgan, D.M. and Satpathy, A.T. and Griffin, G.K. and Lane, A.A. and Love, J.C. and Bernstein, B.E. and Sankaran, V.G. and van Galen, P.
Nature Biotechnology 40 (7): 1030-1034. 24 February 2022

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D. and Ramberger, E. and Bohl, S.R. and Dolnik, A. and Steinebach, C. and Conrad, T. and Müller, S. and Popp, O. and Kull, M. and Haji, M. and Gütschow, M. and Döhner, H. and Walther, W. and Keller, U. and Bullinger, L. and Mertins, P. and Krönke, J.
Nature Communications 13 (1): 1009. 23 February 2022

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K. and Leunig, A. and Kaiser, R. and Joppich, M. and Brambs, S. and Janjic, A. and Popp, O. and Nixdorf, D. and Fumagalli, V. and Schmidt, N. and Polewka, V. and Anjum, A. and Knottenberg, V. and Eivers, L. and Wange, L.E. and Gold, C. and Kirchner, M. and Muenchhoff, M. and Hellmuth, J.C. and Scherer, C. and Rubio-Acero, R. and Eser, T. and Deák, F. and Puchinger, K. and Kuhl, N. and Linder, A. and Saar, K. and Tomas, L. and Schulz, C. and Wieser, A. and Enard, W. and Kroidl, I. and Geldmacher, C. and von Bergwelt-Baildon, M. and Keppler, O.T. and Munschauer, M. and Iannacone, M. and Zimmer, R. and Mertins, P. and Hubner, N. and Hoelscher, M. and Massberg, S. and Stark, K. and Nicolai, L.
Nature Communications 13 (1): 1018. 23 February 2022

Targeting angiotensin type 2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice.
Mohammed, M. and Johnson, D.N. and Wang, L.A. and Harden, S.W. and Sheng, W. and Spector, E.A. and Elsaafien, K. and Bader, M. and Steckelings, U.M. and Scott, K.A. and Frazier, C.J. and Sumners, C. and Krause, E.G. and de Kloet, A.D.
Cardiovascular Research 118 (3): 883-896. 21 February 2022

Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O. and Zincke, F. and Eckert, A. and Kobelt, D. and Preissner, S. and Liebeskind, J.M. and Gunkel, N. and Putzker, K. and Lewis, J. and Preissner, S. and Kortüm, B. and Walther, W. and Mura, K. and Bourne, P.E. and Stein, U. and Preissner, R.
Clinical and Translational Medicine 12 (2): e726. 20 February 2022

SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Reincke, S.M. and Yuan, M. and Kornau, H.C. and Corman, V.M. and van Hoof, S. and Sánchez-Sendin, E. and Ramberger, M. and Yu, W. and Hua, Y. and Tien, H. and Schmidt, M.L. and Schwarz, T. and Jeworowski, L.M. and Brandl, S.E. and Rasmussen, H.F. and Homeyer, M.A. and Stöffler, L. and Barner, M. and Kunkel, D. and Huo, S. and Horler, J. and von Wardenburg, N. and Kroidl, I. and Eser, T.M. and Wieser, A. and Geldmacher, C. and Hoelscher, M. and Gänzer, H. and Weiss, G. and Schmitz, D. and Drosten, C. and Prüss, H. and Wilson, I.A. and Kreye, J.
Science 375 (6582): 782-787. 18 February 2022

Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R. and Dickinson, M. and Purtill, D. and Barba, P. and Santoro, A. and Hamad, N. and Kato, K. and Sureda, A. and Greil, R. and Thieblemont, C. and Morschhauser, F. and Janz, M. and Flinn, I. and Rabitsch, W. and Kwong, Y.L. and Kersten, M.J and Minnema, M.C. and Holte, H. and Chan, E.H.L. and Martinez-Lopez, J. and Müller, A.M.S. and Maziarz, R.T. and McGuirk, J.P. and Bachy, E. and Le Gouill, S. and Dreyling, M. and Harigae, H. and Bond, D. and Andreadis, C. and McSweeney, P. and Kharfan-Dabaja, M. and Newsome, S. and Degtyarev, E. and Awasthi, R. and Del Corral, C. and Andreola, G. and Masood, A. and Schuster, S.J. and Jäger, U. and Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386 (7): 629-639. 17 February 2022

Microbiome and metabolome features of the cardiometabolic disease spectrum.
Fromentin, S. and Forslund, S.K. and Chechi, K. and Aron-Wisnewsky, J. and Chakaroun, R. and Nielsen, T. and Tremaroli, V. and Ji, B. and Prifti, E. and Myridakis, A. and Chilloux, J. and Andrikopoulos, P. and Fan, Y. and Olanipekun, M.T. and Alves, R. and Adiouch, S. and Bar, N. and Talmor-Barkan, Y. and Belda, E. and Caesar, R. and Coelho, L.P. and Falony, G. and Fellahi, S. and Galan, P. and Galleron, N. and Helft, G. and Hoyles, L. and Isnard, R. and Le Chatelier, E. and Julienne, H. and Olsson, L. and Pedersen, H.K. and Pons, N. and Quinquis, B. and Rouault, C. and Roume, H. and Salem, J.E. and Schmidt, T.S.B. and Vieira-Silva, S. and Li, P. and Zimmermann-Kogadeeva, M. and Lewinter, C. and Søndertoft, N.B. and Hansen, T.H. and Gauguier, D. and Gøtze, J.P. and Køber, L. and Kornowski, R. and Vestergaard, H. and Hansen, T. and Zucker, J.D. and Hercberg, S. and Letunic, I. and Bäckhed, F. and Oppert, J.M. and Nielsen, J. and Raes, J. and Bork, P. and Stumvoll, M. and Segal, E. and Clément, K. and Dumas, M.E. and Ehrlich, S.D. and Pedersen, O.
Nature Medicine 28 (2): 303-314. 17 February 2022

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M. and Schwarzer, A. and Jayavelu, A.K. and Hsu, C.J. and Kirkpatrick, J. and Döhner, K. and Perner, F. and Eifert, T. and Huber, N. and Arreba-Tutusaus, P. and Dolnik, A. and Assi, S.A. and Nafria, M. and Jiang, L. and Dai, Y.T. and Chen, Z. and Chen, S.J. and Kellaway, S.G. and Ptasinska, A. and Ng, E.S. and Stanley, E.G. and Elefanty, A.G. and Buschbeck, M. and Bierhoff, H. and Brodt, S. and Matziolis, G. and Fischer, K.D. and Hochhaus, A. and Chen, C.W. and Heidenreich, O. and Mann, M. and Lane, S.W. and Bullinger, L. and Ori, A. and von Eyss, B. and Bonifer, C. and Heidel, F.
Blood 139 (7): 1080-1097. 17 February 2022

Novel targets, treatments, and advanced models for intracerebral haemorrhage.
Zille, M. and Farr, T.D. and Keep, R.F. and Römer, C. and Xi, G. and Boltze, J.
EBioMedicine 76 : 103880. 12 February 2022

Shedding light on ecDNA behavior using CRISPR-based live-cell imaging.
Henssen, A.G.
Cancer Discovery 12 (2): 293-295. 9 February 2022

Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism.
Haghikia, A. and Zimmermann, F. and Schumann, P. and Jasina, A. and Roessler, J. and Schmidt, D. and Heinze, P. and Kaisler, J. and Nageswaran, V. and Aigner, A. and Ceglarek, U. and Cineus, R. and Hegazy, A.N. and van der Vorst, E.P.C. and Döring, Y. and Strauch, C.M. and Nemet, I. and Tremaroli, V. and Dwibedi, C. and Kränkel, N. and Leistner, D.M. and Heimesaat, M.M. and Bereswill, S. and Rauch, G. and Seeland, U. and Soehnlein, O. and Müller, D.N. and Gold, R. and Bäckhed, F. and Hazen, S.L. and Haghikia, A. and Landmesser, U.
European Heart Journal 43 (6): ehab644. 7 February 2022

Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg, P. and Astaburuaga-García, R. and Bonaguro, L. and Brumhard, S. and Michalick, L. and Lippert, L.J. and Kostevc, T. and Gäbel, C. and Schneider, M. and Streitz, M. and Demichev, V. and Gemünd, I. and Barone, M. and Tober-Lau, P. and Helbig, E.T. and Hillus, D. and Petrov, L. and Stein, J. and Dey, H.P. and Paclik, D. and Iwert, C. and Mülleder, M. and Aulakh, S.K. and Djudjaj, S. and Bülow, R.D. and Mei, H.E. and Schulz, A.R. and Thiel, A. and Hippenstiel, S. and Saliba, A.E. and Eils, R. and Lehmann, I. and Mall, M.A. and Stricker, S. and Röhmel, J. and Corman, V.M. and Beule, D. and Wyler, E. and Landthaler, M. and Obermayer, B. and von Stillfried, S. and Boor, P. and Demir, M. and Wesselmann, H. and Suttorp, N. and Uhrig, A. and Müller-Redetzky, H. and Nattermann, J. and Kuebler, W.M. and Meisel, C. and Ralser, M. and Schultze, J.L. and Aschenbrenner, A.C. and Thibeault, C. and Kurth, F. and Sander, L.E. and Blüthgen, N. and Sawitzki, B.
Cell 185 (3): 493-512. 3 February 2022

Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load.
Kaneshige, A. and Kaji, T. and Zhang, L. and Saito, H. and Nakamura, A. and Kurosawa, T. and Ikemoto-Uezumi, M. and Tsujikawa, K. and Seno, S. and Hori, M. and Saito, Y. and Matozaki, T. and Maehara, K. and Ohkawa, Y. and Potente, M. and Watanabe, S. and Braun, T. and Uezumi, A. and Fukada, S.I.
Cell Stem Cell 29 (2): 265-280. 3 February 2022

Effect of atmospheric aging on soot particle toxicity in lung cell models at the air-liquid interface: differential toxicological impacts of biogenic and anthropogenic secondary organic aerosols (SOAs).
Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Martens, P. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Pardo, M. and Gröger, T. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Rudich, Y. and Zimmermann, R.
Environmental Health Perspectives 130 (2): 27003. 3 February 2022

Gating choreography and mechanism of the human proton-activated chloride channel ASOR.
Wang, C. and Polovitskaya, M.M. and Delgado, B.D. and Jentsch, T.J. and Long, S.B.
Science Advances 8 (5): eabm3942. 2 February 2022

Determinants of expression of SARS-CoV-2 entry related genes in upper and lower airways.
Aliee, H. and Massip, F. and Qi, C. and de Biase, M.S. and van Nijnatten, J. and Kersten, E.T.G. and Kermani, N.Z. and Khuder, B. and Vonk, J.M. and Vermeulen, R.C.H. and Neighbors, M. and Tew, G.W. and Grimbaldeston, M.A. and Ten Hacken, N.H.T. and Hu, S. and Guo, Y. and Zhang, X. and Sun, K. and Hiemstra, P.S. and Ponder, B.A. and Mäkelä, M.J. and Malmström, K. and Rintoul, R.C. and Reyfman, P.A. and Theis, F.J. and Brandsma, C.A. and Adcock, I.M. and Timens, W. and Xu, C.J. and van den Berge, M. and Schwarz, R.F. and Koppelman, G.H. and Nawijn, M.C. and Faiz, A.
Allergy 77 (2): 690-694. February 2022

The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.
Buffenstein, R. and Amoroso, V. and Andziak, B. and Avdieiev, S. and Azpurua, J. and Barker, A.J. and Bennett, N.C. and Brieño-Enríquez, M.A. and Bronner, G.N. and Coen, C. and Delaney, M.A. and Dengler-Crish, C.M. and Edrey, Y.H. and Faulkes, C.G. and Frankel, D. and Friedlander, G. and Gibney, P.A. and Gorbunova, V. and Hine, C. and Holmes, M.M. and Jarvis, J.U.M. and Kawamura, Y. and Kutsukake, N. and Kenyon, C. and Khaled, W.T. and Kikusui, T. and Kissil, J. and Lagestee, S. and Larson, J. and Lauer, A. and Lavrenchenko, L.A. and Lee, A. and Levitt, J.B. and Lewin, G.R. and Lewis Hardell, K.N. and Lin, T.D. and Mason, M.J. and McCloskey, D. and McMahon, M. and Miura, K. and Mogi, K. and Narayan, V. and O'Connor, T.P. and Okanoya, K. and O'Riain, M.J. and Park, T.J. and Place, N.J. and Podshivalova, K. and Pamenter, M.E. and Pyott, S.J. and Reznick, J. and Ruby, J.G. and Salmon, A.B. and Santos-Sacchi, J. and Sarko, D.K. and Seluanov, A. and Shepard, A. and Smith, M. and Storey, K.B. and Tian, X. and Vice, E.N. and Viltard, M. and Watarai, Ak. and Wywial, E. and Yamakawa, M. and Zemlemerova, E.D. and Zions, M. and Smith, E.S.J.
Biological Reviews 97 (1): 115-140. February 2022

Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group.
Damaschin, C. and Goergen, H. and Kreissl, S. and Plütschow, A. and Breywisch, F. and Mathas, S. and Meissner, J. and Sökler, M. and Topp, M.S. and Vucinic, V. and Zimmermann, A. and von Tresckow, B. and Fuchs, M. and Engert, A. and Borchmann, P. and Eichenauer, D.A.
Leukemia 36 (2): 580-582. February 2022

SPFH protein cage - one ring to rule them all.
Daumke, O. and Lewin, G.R.
Cell Research 32 (2): 117-118. February 2022

Simultaneous dimensionality reduction and integration for single-cell ATAC-seq data using deep learning.
Kopp, W. and Akalin, A. and Ohler, U.
Nature Machine Intelligence 4 (2): 162-168. February 2022

Intricacies of single-cell multi-omics data integration.
Rautenstrauch, P. and Vlot, A.H.C. and Saran, S. and Ohler, U.
Trends in Genetics 38 (2): 128-139. February 2022

Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease.
Talmor-Barkan, Y. and Bar, N. and Shaul, A.A. and Shahaf, N. and Godneva, A. and Bussi, Y. and Lotan-Pompan, M. and Weinberger, A. and Shechter, A. and Chezar-Azerrad, C. and Arow, Z. and Hammer, Y. and Chechi, K. and Forslund, S.K. and Fromentin, S. and Dumas, M.E. and Ehrlich, S.D. and Pedersen, O. and Kornowski, R. and Segal, E.
Nature Medicine 28 (2): 295-302. February 2022

The genomic and spatial mobility of extrachromosomal DNA and its implications for cancer therapy.
van Leen, E. and Brückner, L. and Henssen, A.G.
Nature Genetics 54 (2): 107-114. February 2022

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C. and Doebele, C. and Zindel, A. and Lee, K.S. and Rieke, S.A. and Ceribelli, M. and Comoglio, F. and Phelan, J.D. and Wang, J.Q. and Pikman, Y. and Jahn, D. and Häupl, B. and Schneider, C. and Scheich, S. and Tosto, F.A. and Bohnenberger, H. and Stauder, P. and Schnütgen, F. and Slabicki, M. and Coulibaly, Z.A. and Wolf, S. and Bojarczuk, K. and Chapuy, B. and Brandts, C.H. and Stroebel, P. and Lewis, C.A. and Engelke, M. and Xu, X. and Kim, H. and Dang, T.H. and Schmitz, R. and Hodson, D.J. and Stegmaier, K. and Urlaub, H. and Serve, H. and Schmitt, C.A. and Kreuz, F. and Knittel, G. and Rabinowitz, J.D. and Reinhardt, H.C. and Vander Heiden, M.G. and Thomas, C. and Staudt, L.M. and Zenz, T. and Oellerich, T.
Blood 139 (4): 538-553. 27 January 2022

ATACing single cells with phages.
Maschmeyer, P. and Haas, S.
Molecular Cell 82 (2): 234-236. 20 January 2022

Towards the biogeography of prokaryotic genes.
Coelho, L.P. and Alves, R. and Del Río, Á.R. and Myers, P.N. and Cantalapiedra, C.P. and Giner-Lamia, J. and Schmidt, T.S. and Mende, D.R. and Orakov, A. and Letunic, I. and Hildebrand, F. and Van Rossum, T. and Forslund, S.K. and Khedkar, S. and Maistrenko, O.M. and Pan, S. and Jia, L. and Ferretti, P. and Sunagawa, S. and Zhao, X.M. and Nielsen, H.B. and Huerta-Cepas, J. and Bork, P.
Nature 601 (7892): 252-256. 13 January 2022

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
Schick, M. and Zhang, L. and Maurer, S. and Maurer, H.C. and Isaakaidis, K. and Schneider, L. and Patra, U. and Schunck, K. and Rohleder, E. and Hofstetter, J. and Baluapuri, A. and Scherger, A.K. and Slotta-Huspenina, J. and Hettler, F. and Weber, J. and Engleitner, T. and Maresch, R. and Slawska, J. and Lewis, R. and Istvanffy, R. and Habringer, S. and Steiger, K. and Baiker, A. and Oostendorp, R.A.J. and Miething, C. and Lenhof, H.P. and Bassermann, F. and Chapuy, B. and Wirth, M. and Wolf, E. and Rad, R. and Müller, S. and Keller, U.
Nature Communications 13 (1): 281. 12 January 2022

AKAP18δ anchors and regulates CaMKII activity at phospholamban-SERCA2 and RYR.
Carlson, C.R. and Aronsen, J.M. and Bergan-Dahl, A. and Moutty, M.C. and Lunde, M. and Lunde, P.K. and Jarstadmarken, H. and Wanichawan, P. and Pereira, L. and Kolstad, T.R.S. and Dalhus, B. and Subramanian, H. and Hille, S. and Christensen, G. and Müller, O.J. and Nikolaev, V. and Bers, D.M. and Sjaastad, I. and Shen, X. and Louch, W.E. and Klussmann, E. and Sejersted, O.M.
Circulation Research 130 (1): 27-44. 7 January 2022

An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
Hahn, T. and Ernsting, J. and Winter, N.R. and Holstein, V. and Leenings, R. and Beisemann, M. and Fisch, L. and Sarink, K. and Emden, D. and Opel, N. and Redlich, R. and Repple, J. and Grotegerd, D. and Meinert, S. and Hirsch, J.G. and Niendorf, T. and Endemann, B. and Bamberg, F. and Kröncke, T. and Bülow, R. and Völzke, H. and von Stackelberg, O. and Sowade, R.F. and Umutlu, L. and Schmidt, B. and Caspers, S. and Kugel, H. and Kircher, T. and Risse, B. and Gaser, C. and Cole, J.H. and Dannlowski, U. and Berger, K.
Science Advances 8 (1): eabg9471. 7 January 2022

Locus-conserved circular RNA cZNF292 controls endothelial cell flow responses.
Heumüller, A.W. and Jones, A. N. and Mourão, A. and Klangwart, M. and Shi, C. and Wittig, I. and Fischer, A. and Muhly Reinholz, M. and Buchmann, G.K. and Dieterich, C. and Potente, M. and Braun, T. and Grote, P. and Jaé, N. and Sattler, M. and Dimmeler, S.
Circulation Research 130 (1): 67-79. 7 January 2022

CEBPA mutations in AML: site matters.
Bullinger, L.
Blood 139 (1): 6-7. 6 January 2022

A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
Patsalos, A. and Halasz, L. and Medina-Serpas, M.A. and Berger, W.K. and Daniel, B. and Tzerpos, P. and Kiss, M. and Nagy, G. and Fischer, C. and Simandi, Z. and Varga, T. and Nagy, L.
Journal of Experimental Medicine 219 (1): e20210420. 3 January 2022

Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
Rücker, F.G. and Du, L. and Luck, T.J. and Benner, A. and Krzykalla, J. and Gathmann, I. and Voso, M.T. and Amadori, S. and Prior, T.W. and Brandwein, J.M. and Appelbaum, F.R. and Medeiros, B.C. and Tallman, M.S. and Savoie, L. and Sierra, J. and Pallaud, C. and Sanz, M.A. and Jansen, J.H. and Niederwieser, D. and Fischer, T. and Ehninger, G. and Heuser, M. and Ganser, A. and Bullinger, L. and Larson, R.A. and Bloomfield, C.D. and Stone, R.M. and Döhner, H. and Thiede, C. and Döhner, K.
Leukemia 36 (1): 90-99. January 2022

2021

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.
Wendisch, D. and Dietrich, O. and Mari, T. and von Stillfried, S. and Ibarra, I.L. and Mittermaier, M. and Mache, C. and Chua, R.L. and Knoll, R. and Timm, S. and Brumhard, S. and Krammer, T. and Zauber, H. and Hiller, A.L. and Pascual-Reguant, A. and Mothes, R. and Bülow, R.D. and Schulze, J. and Leipold, A.M. and Djudjaj, S. and Erhard, F. and Geffers, R. and Pott, F. and Kazmierski, J. and Radke, J. and Pergantis, P. and Baßler, K. and Conrad, C. and Aschenbrenner, A.C. and Sawitzki, B. and Landthaler, M. and Wyler, E. and Horst, D. and Hippenstiel, S. and Hocke, A. and Heppner, F.L. and Uhrig, A. and Garcia, C. and Machleidt, F. and Herold, S. and Elezkurtaj, S. and Thibeault, C. and Witzenrath, M. and Cochain, C. and Suttorp, N. and Drosten, C. and Goffinet, C. and Kurth, F. and Schultze, J.L. and Radbruch, H. and Ochs, M. and Eils, R. and Müller-Redetzky, H. and Hauser, A.E. and Luecken, M.D. and Theis, F.J. and Conrad, C. and Wolff, T. and Boor, P. and Selbach, M. and Saliba, A.E. and Sander, L.E.
Cell 184 (26): 6243-6261. 22 December 2021

Extracellular matrix in heart Failure: role of ADAMTS5 in proteoglycan remodeling.
Barallobre-Barreiro, J. and Radovits, T. and Fava, M. and Mayr, U. and Lin, W.Y. and Ermolaeva, E. and Martínez-López, D. and Lindberg, E.L. and Duregotti, E. and Daróczi, L. and Hasman, M. and Schmidt, L.E. and Singh, B. and Lu, R. and Baig, F. and Siedlar, A.M. and Cuello, F. and Catibog, N. and Theofilatos, K. and Shah, A.M. and Crespo-Leiro, M.G. and Doménech, N. and Hübner, N. and Merkely, B. and Mayr, M.
Circulation 144 (25): 2021-2034. 21 December 2021

Canagliflozin and myocardial oxidative stress: SGLT1 inhibition takes centre stage.
Schiattarella, G.G. and Bode, D.
European Heart Journal 42 (48): 4961-4963. 21 December 2021

Deep tissue scattering compensation with three-photon F-SHARP.
Berlage, C. and Tantirigama, M.L.S. and Babot, M. and Di Battista, D. and Whitmire, C. and Papadopoulos, I.N. and Poulet, J.F.A. and Larkum, M. and Judkewitz, B.
Optica 8 (12): 1613-1619. 20 December 2021

Combinatorial, additive and dose-dependent drug-microbiome associations.
Forslund, S.K. and Chakaroun, R. and Zimmermann-Kogadeeva, M. and Markó, L. and Aron-Wisnewsky, J. and Nielsen, T. and Moitinho-Silva, L. and Schmidt, T.S.B. and Falony, G. and Vieira-Silva, S. and Adriouch, S. and Alves, R.J. and Assmann, K. and Bastard, J.P. and Birkner, T. and Caesar, R. and Chilloux, J. and Coelho, L.P. and Fezeu, L. and Galleron, N. and Helft, G. and Isnard, R. and Ji, B. and Kuhn, M. and Le Chatelier, E. and Myridakis, A. and Olsson, L. and Pons, N. and Prifti, E. and Quinquis, B. and Roume, H. and Salem, J.E. and Sokolovska, N. and Tremaroli, V. and Valles-Colomer, M. and Lewinter, C. and Søndertoft, N.B. and Pedersen, H.K. and Hansen, T.H. and Gøtze, J.P. and Køber, L. and Vestergaard, H. and Hansen, T. and Zucker, J.D. and Hercberg, S. and Oppert, J.M. and Letunic, I. and Nielsen, J. and Bäckhed, F. and Ehrlich, S.D. and Dumas, M.E. and Raes, J. and Pedersen, O. and Clément, K. and Stumvoll, M. and Bork, P.
Nature 600 : 500-505. 16 December 2021

CARDIOKIN1: computational assessment of myocardial metabolic capability in healthy controls and patients with valve diseases.
Berndt, N. and Eckstein, J. and Wallach, I. and Nordmeyer, S. and Kelm, M. and Kirchner, M. and Goubergrits, L. and Schafstedde, M. and Hennemuth, A. and Kraus, M. and Grune, T. and Mertins, P. and Kuehne, T. and Holzhütter, H.G.
Circulation 144 (24): 1926-1939. 14 December 2021

RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.
Poetz, F. and Corbo, J. and Levdansky, Y. and Spiegelhalter, A. and Lindner, D. and Magg, V. and Lebedeva, S. and Schweiggert, J. and Schott, J. and Valkov, E. and Stoecklin, G.
Nature Communications 12 (1): 7175. 9 December 2021

The SEQC2 epigenomics quality control (EpiQC) study.
Foox, J. and Nordlund, J. and Lalancette, C. and Gong, T. and Lacey, M. and Lent, S. and Langhorst, B.W. and Ponnaluri, V.K.C. and Williams, L. and Padmanabhan, K.R. and Cavalcante, R. and Lundmark, A. and Butler, D. and Mozsary, C. and Gurvitch, J. and Greally, J.M. and Suzuki, M. and Menor, M. and Nasu, M. and Alonso, A. and Sheridan, C. and Scherer, A. and Bruinsma, S. and Golda, G. and Muszynska, A. and Łabaj, P.P. and Campbell, M.A. and Wos, F. and Raine, A. and Liljedahl, U. and Axelsson, T. and Wang, C. and Chen, Z. and Yang, Z. and Li, J. and Yang, X. and Wang, H. and Melnick, A. and Guo, S. and Blume, A. and Franke, V. and Ibanez de Caceres, I. and Rodriguez-Antolin, C. and Rosas, R. and Davis, J.W. and Ishii, J. and Megherbi, D.B. and Xiao, W. and Liao, W. and Xu, J. and Hong, H. and Ning, B. and Tong, W. and Akalin, A. and Wang, Y. and Deng, Y. and Mason, C.E.
Genome Biology 22 (1): 332. 6 December 2021

Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq.
Glaser, L.V. and Steiger, M. and Fuchs, A. and van Bömmel, A. and Einfeldt, E. and Chung, H.R. and Vingron, M. and Meijsing, S.H.
Nucleic Acids Research 49 (21): 12178-12195. 2 December 2021

Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K. and Kny, M. and Huang, N. and Klassert, T.E. and Stock, M. and Hahn, A. and Graeger, S. and Todiras, M. and Schmidt, S. and Chamling, B. and Willenbrock, M. and Groß, S. and Biedenweg, D. and Heuser, A. and Scheidereit, C. and Butter, C. and Felix, S.B. and Otto, O. and Luft, F.C. and Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12 (6): 1653-1668. December 2021

Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women.
Hur, J. and Otegbeye, E. and Joh, H.K. and Nimptsch, K. and Ng, K. and Ogino, S. and Meyerhardt, J.A. and Chan, A.T. and Willett, W.C. and Wu, K. and Giovannucci, E. and Cao, Y.
Gut 70 (12): 2330-2336. December 2021

Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide - an international collaborative study.
Kayser, S. and Schlenk, R.F. and Lebon, D. and Carre, M. and Götze, K.S. and Stölzel, F. and Berceanu, A. and Schäfer-Eckart, K. and Peterlin, P. and Hicheri, Y. and Rahme, R. and Raffoux, E. and Chermat, F. and Krause, S.W. and Aulitzky, W.E. and Rigaudeau, S. and Noppeney, R. and Berthon, C. and Görner, M. and Jost, E. and Carassou, P. and Keller, U. and Orvain, C. and Braun, T. and Saillard, C. and Arar, A. and Kunzmann, V. and Wemeau, M. and De Wit, M. and Niemann, D. and Bonmati, C. and Schwänen, C. and Abraham, J. and Aljijakli, A. and Haiat, S. and Krämer, A. and Reichle, A. and Gnadler, M. and Willekens, C. and Spiekermann, K. and Hiddemann, W. and Müller-Tidow, C. and Thiede, C. and Röllig, C. and Serve, H. and Bornhäuser, M. and Baldus, C.D. and Lengfelder, E. and Fenaux, P. and Platzbecker, U. and Adès, L.
Haematologica 106 (12): 3100-3106. December 2021

Longitudinal single-cell dynamics of chromatin accessibility and mitochondrial mutations in chronic lymphocytic leukemia mirror disease history.
Penter, L. and Gohil, S.H. and Lareau, C. and Ludwig, L.S. and Parry, E.M. and Huang, T. and Li, S. and Zhang, W. and Livitz, D. and Leshchiner, I. and Parida, L. and Getz, G. and Rassenti, L.Z. and Kipps, T.J. and Brown, J.R. and Davids, M.S. and Neuberg, D.S. and Livak, K.J. and Sankaran, V.G. and Wu, C.J.
Cancer Discovery 11 (12): 3048-3063. December 2021

Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue.
Radke, M.H. and Badillo-Lisakowski, V. and Britto-Borges, T. and Kubli, D.A. and Jüttner, R. and Parakkat, P. and Lopez Carballo, J. and Hüttemeister, J. and Liss, M. and Hansen, A. and Dieterich, C. and Mullick, A.E. and Gotthardt, M.
Science Translational Medicine 13 (622): eabe8952. December 2021

Chromothripsis followed by circular recombination drives oncogene amplification in human cancer.
Rosswog, C. and Bartenhagen, C. and Welte, A. and Kahlert, Y. and Hemstedt, N. and Lorenz, W. and Cartolano, M. and Ackermann, S. and Perner, S. and Vogel, W. and Altmüller, J. and Nürnberg, P. and Hertwig, F. and Göhring, G. and Lilienweiss, E. and Stütz, A.M. and Korbel, J.O. and Thomas, R.K. and Peifer, M. and Fischer, M.
Nature Genetics 53 (12): 1673–1685. December 2021

Compendium of 530 metagenome-assembled bacterial and archaeal genomes from the polar Arctic Ocean.
Royo-Llonch, M. and Sánchez, P. and Ruiz-González, C. and Salazar, G. and Pedrós-Alió, C. and Sebastián, M. and Labadie, K. and Paoli, L. and M. Ibarbalz, F. and Zinger, L. and Churcheward, B. and Chaffron, S. and Eveillard, D. and Karsenti, E. and Sunagawa, S. and Wincker, P. and Karp-Boss, L. and Bowler, C. and Acinas, S.G.
Nature Microbiology 6 (12): 1561-1574. December 2021

Diabetic pregnancy as a novel risk factor for cardiac dysfunction in the offspring-the heart as a target for fetal programming in rats.
Schütte, T. and Kedziora, S.M. and Haase, N. and Herse, F. and Alenina, N. and Müller, D.N. and Bader, M. and Schupp, M. and Dechend, R. and Golic, M. and Kräker, K.
Diabetologia 64 (12): 2829-2842. December 2021

Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.
Triana, S. and Vonficht, D. and Jopp-Saile, L. and Raffel, S. and Lutz, R. and Leonce, D. and Antes, M. and Hernández-Malmierca, P. and Ordoñez-Rueda, D. and Ramasz, B. and Boch, T. and Jann, J.C. and Nowak, D. and Hofmann, W.K. and Müller-Tidow, C. and Hübschmann, D. and Alexandrov, T. and Benes, V. and Trumpp, A. and Paulsen, M. and Velten, L. and Haas, S.
Nature Immunology 22 (12): 1577-1589. December 2021

Cell-type specialization is encoded by specific chromatin topologies.
Winick-Ng, W. and Kukalev, A. and Harabula, I. and Zea-Redondo, L. and Szabó, D. and Meijer, M. and Serebreni, L. and Zhang, Y. and Bianco, S. and Chiariello, A.M. and Irastorza-Azcarate, I. and Thieme, C.J. and Sparks, T.M. and Carvalho, S. and Fiorillo, L. and Musella, F. and Irani, E. and Triglia, E.T. and Kolodziejczyk, A.A. and Abentung, A. and Apostolova, G. and Paul, E.J. and Franke, V. and Kempfer, R. and Akalin, A. and Teichmann, S.A. and Dechant, G. and Ungless, M.A. and Nicodemi, M. and Welch, L. and Castelo-Branco, G. and Pombo, A.
Nature 599 (7886): 684-691. 25 November 2021

Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Schmelz, K. and Toedling, J. and Huska, M. and Cwikla, M.C. and Kruetzfeldt, L.M. and Proba, J. and Ambros, P.F. and Ambros, I.M. and Boral, S. and Lodrini, M. and Chen, C.Y. and Burkert, M. and Guergen, D. and Szymansky, A. and Astrahantseff, K. and Kuenkele, A. and Haase, K. and Fischer, M. and Deubzer, H.E. and Hertwig, F. and Hundsdoerfer, P. and Henssen, A.G. and Schwarz, R.F. and Schulte, J.H. and Eggert, A.
Nature Communications 12 (1): 6804. 23 November 2021

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.
Grosche, S. and Marenholz, I. and Esparza-Gordillo, J. and Arnau-Soler, A. and Pairo-Castineira, E. and Rüschendorf, F. and Ahluwalia, T.S. and Almqvist, C. and Arnold, A. and Baurecht, H. and Bisgaard, H. and Bønnelykke, K. and Brown, S.J. and Bustamante, M. and Curtin, J.A. and Custovic, A. and Dharmage, S.C. and Esplugues, A. and Falchi, M. and Fernandez-Orth, D. and Ferreira, M.A.R. and Franke, A. and Gerdes, S. and Gieger, C. and Hakonarson, H. and Holt, P.G. and Homuth, G. and Hubner, N. and Hysi, P.G. and Jarvelin, M.R. and Karlsson, R. and Koppelman, G.H. and Lau, S. and Lutz, M. and Magnusson, P.K.E. and Marks, G.B. and Müller-Nurasyid, M. and Nöthen, M.M. and Paternoster, L. and Pennell, C.E. and Peters, A. and Rawlik, K. and Robertson, C.F. and Rodriguez, E. and Sebert, S. and Simpson, A. and Sleiman, P.M.A. and Standl, M. and Stölzl, D. and Strauch, K. and Szwajda, A. and Tenesa, A. and Thompson, P.J. and Ullemar, V. and Visconti, A. and Vonk, J.M. and Wang, C.A. and Weidinger, S. and Wielscher, M. and Sargent, C.L. and Xu, C.J. and Lee, Y.A.
Nature Communications 12 (1): 6618. 16 November 2021

Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression.
Pott, F. and Postmus, D. and Brown, R.J.P. and Wyler, E. and Neumann, E. and Landthaler, M. and Goffinet, C.
Emerging Microbes & Infections 10 (1): 2151-2168. 16 November 2021

Heart failure with preserved ejection fraction in humans and mice: embracing clinical complexity in mouse models.
Withaar, C. and Lam, C.S.P. and Schiattarella, G.G. and de Boer, R.A. and Meems, L.M.G.
European Heart Journal 42 (43): 4420-4430. 14 November 2021

Virus-induced senescence is driver and therapeutic target in COVID-19.
Lee, S. and Yu, Y. and Trimpert, J. and Benthani, F. and Mairhofer, M. and Richter-Pechanska, P. and Wyler, E. and Belenki, D. and Kaltenbrunner, S. and Pammer, M. and Kausche, L. and Firsching, T.C. and Dietert, K. and Schotsaert, M. and Martínez-Romero, C. and Singh, G. and Kunz, S. and Niemeyer, D. and Ghanem, R. and Salzer, H.J.F. and Paar, C. and Mülleder, M. and Uccellini, M. and Michaelis, E.G. and Khan, A. and Lau, A. and Schönlein, M. and Habringer, A. and Tomasits, J. and Adler, J.M. and Kimeswenger, S. and Gruber, A.D. and Hoetzenecker, W. and Steinkellner, H. and Purfuerst, B. and Motz, R. and Di Pierro, F. and Lamprecht, B. and Osterrieder, N. and Landthaler, M. and Drosten, C. and García-Sastre, A. and Langer, R. and Ralser, M. and Eils, R. and Reimann, M. and Fan, D.N.Y. and Schmitt, C.A.
Nature 599 : 283-289. 11 November 2021

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Krämer, B. and Knoll, R. and Bonaguro, L. and ToVinh, M. and Raabe, J. and Astaburuaga-García, R. and Schulte-Schrepping, J. and Kaiser, K.M. and Rieke, G.J. and Bischoff, J. and Monin, M.B. and Hoffmeister, C. and Schlabe, S. and De Domenico, E. and Reusch, N. and Händler, K. and Reynolds, G. and Blüthgen, N. and Hack, G. and Finnemann, C. and Nischalke, H.D. and Strassburg, C.P. and Stephenson, E. and Su, Y. and Gardner, L. and Yuan, D. and Chen, D. and Goldman, J. and Rosenstiel, P. and Schmidt, S.V. and Latz, E. and Hrusovsky, K. and Ball, A.J. and Johnson, J.M. and Koenig, P.A. and Schmidt, F.I. and Haniffa, M. and Heath, J.R. and Kümmerer, B.M. and Keitel, V. and Jensen, B. and Stubbemann, P. and Kurth, F. and Sander, L.E. and Sawitzki, B. and Aschenbrenner, A.C. and Schultze, J.L. and Nattermann, J.
Immunity 54 (11): 2650-2669. 9 November 2021

Lysine acetylation regulates the interaction between proteins and membranes.
Okada, A.K. and Teranishi, K. and Ambroso, M.R. and Isas, J.M. and Vazquez-Sarandeses, E. and Lee, J.Y. and Melo, A.A. and Pandey, P. and Merken, D. and Berndt, L. and Lammers, M. and Daumke, O. and Chang, K. and Haworth, I.S. and Langen, R.
Nature Communications 12 (1): 6466. 9 November 2021

Unravelling the collateral damage of antibiotics on gut bacteria.
Maier, L. and Goemans, C.V. and Wirbel, J. and Kuhn, M. and Eberl, C. and Pruteanu, M. and Müller, P. and Garcia-Santamarina, S. and Cacace, E. and Zhang, B. and Gekeler, C. and Banerjee, T. and Anderson, E.E. and Milanese, A. and Löber, U. and Forslund, S.K. and Patil, K.R. and Zimmermann, M. and Stecher, B. and Zeller, G. and Bork, P. and Typas, A.
Nature 599 : 120-124. 4 November 2021

Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations.
Fomin, A. and Gärtner, A. and Cyganek, L. and Tiburcy, M. and Tuleta, I. and Wellers, L. and Folsche, L. and Hobbach, A.J. and von Frieling-Salewsky, M. and Unger, A. and Hucke, A. and Koser, F. and Kassner, A. and Sielemann, K. and Streckfuß-Bömeke, K. and Hasenfuss, G. and Goedel, A. and Laugwitz, K.L. and Moretti, A. and Gummert, J.F. and Dos Remedios, C.G. and Reinecke, H. and Knöll, R. and van Heesch, S. and Hubner, N. and Zimmermann, W.H. and Milting, H. and Linke, W.A.
Science Translational Medicine 13 (618): eabd3079. 3 November 2021

A medullary centre for lapping in mice.
Dempsey, B. and Sungeelee, S. and Bokiniec, P. and Chettouh, Z. and Diem, S. and Autran, S. and Harrell, E.R. and Poulet, J.F.A. and Birchmeier, C. and Carey, H. and Genovesio, A. and McMullan, S. and Goridis, C. and Fortin, G. and Brunet, J.F.
Nature Communications 12 : 6307. 2 November 2021

Encephalitis patient-derived monoclonal GABA(A) receptor antibodies cause epileptic seizures.
Kreye, J. and Wright, S.K. and van Casteren, A. and Stoeffler, L. and Machule, M.L. and Reincke, S.M. and Nikolaus, M. and van Hoof, S. and Sanchez-Sendin, E. and Homeyer, M.A. and Gómez, C.C. and Kornau, H.C. and Schmitz, D. and Kaindl, A.M. and Boehm-Sturm, P. and Mueller, S. and Wilson, M.A. and Upadhya, M.A. and Dhangar, D.R. and Greenhill, S. and Woodhall, G. and Turko, P. and Vida, I. and Garner, C.C. and Wickel, J. and Geis, C. and Fukata, Y. and Fukata, M. and Prüss, H.
Journal of Experimental Medicine 218 (11): e20210012. 1 November 2021

A comparison of metabolic labeling and statistical methods to infer genome-wide dynamics of RNA turnover.
Boileau, E. and Altmüller, J. and Naarmann-de Vries, I.S. and Dieterich, C.
Briefings in Bioinformatics 22 (6): bbab219. November 2021

Reporting guidelines for human microbiome research: the STORMS checklist.
Mirzayi, C. and Renson, A. and Zohra, F. and Elsafoury, S. and Geistlinger, L. and Kasselman, L.J. and Eckenrode, K. and van de Wijgert, J. and Loughman, A. and Marques, F.Z. and MacIntyre, D.A. and Arumugam, M. and Azhar, R. and Beghini, F. and Bergstrom, K. and Bhatt, A. and Bisanz, J.E. and Braun, J. and Bravo, H.C. and Buck, G.A. and Bushman, F. and Casero, D. and Clarke, G. and Collado, M.C. and Cotter, P.D. and Cryan, J.F. and Demmer, R.T. and Devkota, S. and Elinav, E. and Escobar, J.S. and Fettweis, J. and Finn, R.D. and Fodor, A.A. and Forslund, S. and Franke, A. and Furlanello, C. and Gilbert, J. and Grice, E. and Haibe-Kains, B. and Handley, S. and Herd, P. and Holmes, S. and Jacobs, J.P. and Karstens, L. and Knight, R. and Knights, D. and Koren, O. and Kwon, D.S. and Langille, M. and Lindsay, B. and McGovern, D. and McHardy, A.C. and McWeeney, S. and Mueller, N.T. and Nezi, L. and Olm, M. and Palm, N. and Pasolli, E. and Raes, J. and Redinbo, M.R. and Rühlemann, M. and Balfour Sartor, R and Schloss, P.D. and Schriml, L. and Segal, E. and Shardell, M. and Sharpton, T. and Smirnova, E. and Sokol, H. and Sonnenburg, J.L. and Srinivasan, S. and Thingholm, L.B. and Turnbaugh, P.J. and Upadhyay, V. and Walls, R.L. and Wilmes, P. and Yamada, T. and Zeller, G. and Zhang, M. and Zhao, N. and Zhao, L. and Bao, W. and Culhane, A. and Devanarayan, V. and Dopazo, J. and Fan, X. and Fischer, M. and Jones, W. and Kusko, R. and Mason, C.E. and Mercer, T.R. and Sansone, S.A. and Scherer, A. and Shi, L. and Thakkar, S. and Tong, W. and Wolfinger, R. and Hunter, C. and Segata, N. and Huttenhower, C. and Dowd, J.B. and Jones, H.E. and Waldron, L.
Nature Medicine 27 (11): 1885-1892. November 2021

Cannabidiol converts NF(κ)B into a tumor suppressor in glioblastoma with defined antioxidative properties.
Volmar, M.N.M. and Cheng, J. and Alenezi, H. and Richter, S. and Haug, A. and Hassan, Z. and Goldberg, M. and Li, Y. and Hou, M. and Herold-Mende, C. and Maire, C.L. and Lamszus, K. and Flüh, C. and Held-Feindt, J. and Gargiulo, G. and Topping, G.J. and Schilling, F. and Saur, D. and Schneider, G. and Synowitz, M. and Schick, J.A. and Kälin, R.E. and Glass, R.
Neuro-Oncology 23 (11): 1898-1910. November 2021

Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Dahlmann, M. and Gambara, G. and Brzezicha, B. and Popp, O. and Pachmayr, E. and Wedeken, L. and Pflaume, A. and Mokritzkij, M. and Gül-Klein, S. and Brandl, A. and Schweiger-Eisbacher, C. and Mertins, P. and Hoffmann, J. and Keilholz, U. and Walther, W. and Regenbrecht, C. and Rau, B. and Stein, U.
Molecular Cancer 20 (1): 129. 21 October 2021

PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel, L.M. and Franke, V. and Bruno, M. and Grishkovskaya, I. and Kasiliauskaite, A. and Kaufmann, T. and Schoeberl, U.E. and Puchinger, M.G. and Kostrhon, S. and Ebenwaldner, C. and Sebesta, M. and Beltzung, E. and Mechtler, K. and Lin, G. and Vlasova, A. and Leeb, M. and Pavri, R. and Stark, A. and Akalin, A. and Stefl, R. and Bernecky, C. and Djinovic-Carugo, K. and Slade, D.
Nature Communications 12 (1): 6078. 19 October 2021

Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis.
Schmidt, O. and Nehls, N. and Prexler, C. and von Heyking, K. and Groll, T. and Pardon, K. and Garcia, H.D. and Hensel, T. and Gürgen, D. and Henssen, A.G. and Eggert, A. and Steiger, K. and Burdach, S. and Richter, G.H.S.
Journal of Experimental & Clinical Cancer Research 40 (1): 322. 15 October 2021

Age-related decline in murine heart and skeletal muscle performance is attenuated by reduced Ahnak1 expression.
Mahmoodzadeh, S. and Koch, K. and Schriever, C. and Xu, J. and Steinecker, M. and Leber, J. and Dworatzek, E. and Purfürst, B. and Kunz, S. and Recchia, D. and Canepari, M. and Heuser, A. and Di Francescantonio, S. and Morano, I.
Journal of Cachexia Sarcopenia and Muscle 12 : 1249-1265. 14 October 2021

Human and preclinical studies of the host-gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health.
Brial, F. and Chilloux, J. and Nielsen, T. and Vieira-Silva, S. and Falony, G. and Andrikopoulos, P. and Olanipekun, M. and Hoyles, L. and Djouadi, F. and Neves, A.L. and Rodriguez-Martinez, A. and Mouawad, G.I. and Pons, N. and Forslund, S. and Le-Chatelier, E. and Le Lay, A. and Nicholson, J. and Hansen, T. and Hyötyläinen, T. and Clément, K. and Oresic, M. and Bork, P. and Ehrlich, S.D. and Raes, J. and Pedersen, O.B. and Gauguier, D. and Dumas, M.E.
Gut 70 (11): 2105-2114. 7 October 2021

Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.
Uhlitz, F. and Bischoff, P. and Peidli, S. and Sieber, A. and Trinks, A. and Lüthen, M. and Obermayer, B. and Blanc, E. and Ruchiy, Y. and Sell, T. and Mamlouk, S. and Arsie, R. and Wei, T.T. and Klotz-Noack, K. and Schwarz, R.F. and Sawitzki, B. and Kamphues, C. and Beule, D. and Landthaler, M. and Sers, C. and Horst, D. and Blüthgen, N. and Morkel, M.
EMBO Molecular Medicine 13 (10): e14123. 7 October 2021

Targeted diets for the gut microbiota and the potential cardiovascular effects.
Chiva-Blanch, G. and Mueller, D.N.
Cardiovascular Research 117 (11): e135–e137. 1 October 2021

Recurrent frameshift neoantigen vaccine elicits protective immunity with reduced tumor burden and improved overall survival in a Lynch syndrome mouse model.
Gebert, J. and Gelincik, O. and Oezcan-Wahlbrink, M. and Marshall, J.D. and Hernandez-Sanchez, A. and Urban, K. and Long, M. and Cortes, E. and Tosti, E. and Katzenmaier, E.M. and Song, Y. and Elsaadi, A. and Deng, N. and Vilar, E. and Fuchs, V. and Nelius, N. and Yuan, Y.P. and Ahadova, A. and Sei, S. and Shoemaker, R.H. and Umar, A. and Wei, L. and Liu, S. and Bork, P. and Edelmann, W. and von Knebel Doeberitz, M. and Lipkin, S.M. and Kloor, M.
Gastroenterology 161 (4): 288-1302.e13. October 2021

Acute kidney injury in patients treated with immune checkpoint inhibitors.
Gupta, S. and Short, S.A.P. and Sise, M.E. and Prosek, J.M. and Madhavan, S.M. and Soler, M.J. and Ostermann, M. and Herrmann, S.M. and Abudayyeh, A. and Anand, S. and Glezerman, I. and Motwani, S.S. and Murakami, N. and Wanchoo, R. and Ortiz-Melo, D.I. and Rashidi, A. and Sprangers, B. and Aggarwal, V. and Malik, A.B. and Loew, S. and Carlos, C.A. and Chang, W.T. and Beckerman, P. and Mithani, Z. and Shah, C.V. and Renaghan, A.D. and Seigneux, S.D. and Campedel, L. and Kitchlu, A. and Shin, D.S. and Rangarajan, S. and Deshpande, P. and Coppock, G. and Eijgelsheim, M. and Seethapathy, H. and Lee, M.D. and Strohbehn, I.A. and Owen, D.H. and Husain, M. and Garcia-Carro, C. and Bermejo, S. and Lumlertgul, N. and Seylanova, N. and Flanders, L. and Isik, B. and Mamlouk, O. and Lin, J.S. and Garcia, P. and Kaghazchi, A. and Khanin, Y. and Kansal, S.K. and Wauters, E. and Chandra, S. and Schmidt-Ott, K.M. and Hsu, R.K. and Tio, M.C. and Sarvode Mothi, S. and Singh, H. and Schrag, D. and Jhaveri, K.D. and Reynolds, K.L. and Cortazar, F.B. and Leaf, D.E.
Journal for ImmunoTherapy of Cancer 9 (10): e003467. October 2021

Subclone eradication analysis identifies targets for enhanced cancer therapy and reveals L1 retrotransposition as a dynamic source of cancer heterogeneity.
Ketola, K. and Kaljunen, H. and Taavitsainen, S. and Kaarijärvi, R. and Järvelä, E. and Rodriguez Martin, B. and Haase, K. and Woodcock, D.J. and Tubio, J. and Wedge, D.C. and Nykter, M. and Bova, G.S.
Cancer Research 81 (19): 4901-4909. October 2021

CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness.
Lewis, R. and Maurer, H.C. and Singh, N. and Gonzalez-Menendez, I. and Wirth, M. and Schick, M. and Zhang, L. and Isaakidis, K. and Scherger, A.K. and Schulze, V. and Lu, J. and Zenz, T. and Steiger, K. and Rad, R. and Quintanilla-Martinez, L. and Espeli, M. and Balabanian, K. and Keller, U. and Habringer, S.
Leukemia 35 : 2895-2905. October 2021

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Mimitou, E.P. and Lareau, C.A. and Chen, K.Y. and Zorzetto-Fernandes, A.L. and Hao, Y. and Takeshima, Y. and Luo, W. and Huang, T.S. and Yeung, B.Z. and Papalexi, E. and Thakore, P.I. and Kibayashi, T. and Wing, J.B. and Hata, M. and Satija, R. and Nazor, K.L. and Sakaguchi, S. and Ludwig, L.S. and Sankaran, V.G. and Regev, A. and Smibert, P.
Nature Biotechnology 39 (10): 1246-1258. October 2021

Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca, P. and Jäntti, N.Z. and Godbole, R. and Sommer, C. and Jacquemet, G. and Al-Akhrass, H. and Conway, J.R.W. and Kronqvist, P. and Kallionpää, R.E. and Oliveira-Ferrer, L. and Cervero, P. and Linder, S. and Aepfelbacher, M. and Zauber, H. and Rae, J. and Parton, R.G. and Disanza, A. and Scita, G. and Mayor, S. and Selbach, M. and Veltel, S. and Ivaska, J.
Nature Cell Biology 23 (10): 1073-1084. October 2021

Therapy-induced senescence: opportunities to improve anticancer therapy.
Prasanna, P.G. and Citrin, D.E. and Hildesheim, J. and Ahmed, M.M. and Venkatachalam, S. and Riscuta, G. and Xi, D. and Zheng, G. and van Deursen, J. and Goronzy, J. and Kron, S.J. and Anscher, M.S. and Sharpless, N.E. and Campisi, J. and Brown, S.L. and Niedernhofer, L.J. and O'Loghlen, A. and Georgakilas, A.G. and Paris, F. and Gius, D. and Gewirtz, D.A. and Schmitt, C.A. and Abazeed, M.E. and Kirkland, J.L. and Richmond, A. and Romesser, P.B. and Lowe, S.W. and Gil, J. and Mendonca, M.S. and Burma, S. and Zhou, D. and Coleman, C.N.
Journal of the National Cancer Institute 113 (10): 1285-1298. October 2021

Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01.
Weiner, J. and Suwalski, P. and Holtgrewe, M. and Rakitko, A. and Thibeault, C. and Müller, M. and Patriki, D. and Quedenau, C. and Krüger, U. and Ilinsky, V. and Popov, I. and Balnis, J. and Jaitovich, A. and Helbig, E.T. and Lippert, L.J. and Stubbemann, P. and Real, L.M. and Macías, J. and Pineda, J.A. and Fernandez-Fuertes, M. and Wang, X. and Karadeniz, Z. and Saccomanno, J. and Doehn, J.M. and Hübner, R.H. and Hinzmann, B. and Salvo, M. and Blueher, A. and Siemann, S. and Jurisic, S. and Beer, J.H. and Rutishauser, J. and Wiggli, B. and Schmid, H. and Danninger, K. and Binder, R. and Corman, V.M. and Mühlemann, B. and Arjun Arkal, R. and Fragiadakis, G.K. and Mick, E. and Calfee, C.S. and Erle, D.J. and Hendrickson, C.M. and Kangelaris, K.N. and Krummel, M.F. and Woodruff, P.G. and Langelier, C.R. and Venkataramani, U. and García, F. and Zyla, J. and Drosten, C. and Braun, A. and Jones, T.C. and Suttorp, N. and Witzenrath, M. and Hippenstiel, S. and Zemojtel, T. and Skurk, C. and Wolfgang, P. and Borodina, T. and Ripke, S. and Sander, L.E. and Beule, D. and Landmesser, U. and Guettouche, T. and Kurth, F. and Heidecker, B.
EClinicalMedicine 40 : 101099. October 2021

Charcot-Marie-Tooth mutation in glycyl-tRNA synthetase stalls ribosomes in a pre-accommodation state and activates integrated stress response.
Mendonsa, S. and von Kuegelgen, N. and Bujanic, L. and Chekulaeva, M.
Nucleic Acids Research 49 (17): 10007-10017. 27 September 2021

Using DNA sequencing data to quantify T cell fraction and therapy response.
Bentham, R. and Litchfield, K. and Watkins, T.B.K. and Lim, E.L. and Rosenthal, R. and Martínez-Ruiz, C. and Hiley, C.T. and Bakir, M.A. and Salgado, R. and Moore, D.A. and Jamal-Hanjani, M. and Swanton, C. and McGranahan, N.
Nature 597 (7877): 555-560. 23 September 2021

Bioaccumulation of therapeutic drugs by human gut bacteria.
Klünemann, M. and Andrejev, S. and Blasche, S. and Mateus, A. and Phapale, P. and Devendran, S. and Vappiani, J. and Simon, B. and Scott, T.A. and Kafkia, E. and Konstantinidis, D. and Zirngibl, K. and Mastrorilli, E. and Banzhaf, M. and Mackmull, M.T. and Hövelmann, F. and Nesme, L. and Brochado, A.R. and Maier, L. and Bock, T. and Periwal, V. and Kumar, M. and Kim, Y. and Tramontano, M. and Schultz, C. and Beck, M. and Hennig, J. and Zimmermann, M. and Sévin, D.C. and Cabreiro, F. and Savitski, M.M. and Bork, P. and Typas, A. and Patil, K.R.
Nature 597 : 533-538. 23 September 2021

Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma.
Liang, H.C. and Costanza, M. and Prutsch, N. and Zimmerman, M.W. and Gurnhofer, E. and Montes-Mojarro, I.A. and Abraham, B.J. and Prokoph, N. and Stoiber, S. and Tangermann, S. and Lobello, C. and Oppelt, J. and Anagnostopoulos, I. and Hielscher, T. and Pervez, S. and Klapper, W. and Zammarchi, F. and Silva, D.A. and Garcia, K.C. and Baker, D. and Janz, M. and Schleussner, N. and Fend, F. and Pospíšilová, Š. and Janiková, A. and Wallwitz, J. and Stoiber, D. and Simonitsch-Klupp, I. and Cerroni, L. and Pileri, S. and de Leval, L. and Sibon, D. and Fataccioli, V. and Gaulard, P. and Assaf, C. and Knörr, F. and Damm-Welk, C. and Woessmann, W. and Turner, S.D. and Look, A.T. and Mathas, S. and Kenner, L. and Merkel, O.
Nature Communications 12 (1): 5577. 22 September 2021

MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann, J. and Lorenz, C. and Borchmann, S. and Nishii, K. and Wegner, J. and Meder, L. and Ostendorp, J. and Ast, D.F. and Heimsoeth, A. and Nakasuka, T. and Hirabae, A. and Okawa, S. and Dammert, M.A. and Plenker, D. and Klein, S. and Lohneis, P. and Gu, J. and Godfrey, L.K. and Forster, J. and Trajkovic-Arsic, M. and Zillinger, T. and Haarmann, M. and Quaas, A. and Lennartz, S. and Schmiel, M. and D'Rozario, J. and Thomas, E.S. and Li, H. and Schmitt, C.A. and George, J. and Thomas, R.K. and von Karstedt, S. and Hartmann, G. and Büttner, R. and Ullrich, R.T. and Siveke, J.T. and Ohashi, K. and Schlee, M. and Sos, M.L.
Nature Communications 12 (1): 5505. 17 September 2021

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Bloehdorn, J. and Braun, A. and Taylor-Weiner, A. and Jebaraj, B.M.C. and Robrecht, S. and Krzykalla, J. and Pan, H. and Giza, A. and Akylzhanova, G. and Holzmann, K. and Scheffold, A. and Johnston, H.E. and Yeh, R.F. and Klymenko, T. and Tausch, E. and Eichhorst, B. and Bullinger, L. and Fischer, K. and Weisser, M. and Robak, T. and Schneider, C. and Gribben, J. and Dahal, L.N. and Carter, M.J. and Elemento, O. and Landau, D.A. and Neuberg, D.S. and Cragg, M.S. and Benner, A. and Hallek, M. and Wu, C.J. and Döhner, H. and Stilgenbauer, S. and Mertens, D.
Nature Communications 12 (1): 5395. 13 September 2021

CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression.
Franke, M. and De la Calle-Mustienes, E. and Neto, A. and Almuedo-Castillo, M. and Irastorza-Azcarate, I. and Acemel, R.D. and Tena, J.J. and Santos-Pereira, J.M. and Gómez-Skarmeta, J.L.
Nature Communications 12 (1): 5415. 13 September 2021

Humoral and cellular immune responses in SARS-CoV-2 mRNA-vaccinated patients with cancer.
Mairhofer, M. and Kausche, L. and Kaltenbrunner, S. and Ghanem, R. and Stegemann, M. and Klein, K. and Pammer, M. and Rauscher, I. and Salzer, H.J.F. and Doppler, S. and Habringer, A. and Paar, C. and Kimeswenger, S. and Hoetzenecker, W. and Lamprecht, B. and Lee, S. and Schmitt, C.A.
Cancer Cell 39 (9): 1171-1172. 13 September 2021

Locus specific epigenetic modalities of random allelic expression imbalance.
Marion-Poll, L. and Forêt, B. and Zielinski, D. and Massip, F. and Attia, M. and Carter, A.C. and Syx, L. and Chang, H.Y. and Gendrel, A.V. and Heard, E.
Nature Communications 12 (1): 5330. 9 September 2021

Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy.
Sommariva, E. and Stadiotti, I. and Casella, M. and Catto, V. and Dello Russo, A. and Carbucicchio, C. and Arnaboldi, L. and De Metrio, S. and Milano, G. and Scopece, A. and Casaburo, M. and Andreini, D. and Mushtaq, S. and Conte, E. and Chiesa, M. and Birchmeier, W. and Cogliati, E. and Paolin, A. and König, E. and Meraviglia, V. and De Musso, M. and Volani, C. and Cattelan, G. and Rauhe, W. and Turnu, L. and Porro, B. and Pedrazzini, M. and Camera, M. and Corsini, A. and Tondo, C. and Rossini, A. and Pompilio, G.
EMBO Molecular Medicine 13 (9): e14365. 7 September 2021

Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Willnow, D. and Benary, U. and Margineanu, A. and Vignola, M.L. and Konrath, F. and Pongrac, I.M. and Karimaddini, Z. and Vigilante, A. and Wolf, J. and Spagnoli, F.M.
Nature 597 (7874): 87-91. 2 September 2021

NovoSpaRc: flexible spatial reconstruction of single-cell gene expression with optimal transport.
Moriel, N. and Senel, E. and Friedman, N. and Rajewsky, N. and Karaiskos, N. and Nitzan, M.
Nature Protocols 16 (9): 4177-4200. September 2021

Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia.
Rapaport, F. and Neelamraju, Y. and Baslan, T. and Hassane, D. and Gruszczynska, A. and de Massy, M.R. and Farnoud, N. and Haddox, S. and Lee, T. and Medina-Martinez, J. and Sheridan, C. and Thurmond, A. and Becker, M. and Bekiranov, S. and Carroll, M. and Moses Murdock, H. and Valk, P.J.M. and Bullinger, L. and D’Andrea, R. and Lowe, S.W. and Neuberg, D. and Levine, R.L. and Melnick, A. and Garrett-Bakelman, F.E.
Leukemia 35 (9): 2688-2692. September 2021

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.
Diener, J. and Baggiolini, A. and Pernebrink, M. and Dalcher, D. and Lerra, L. and Cheng, P.F. and Varum, S. and Häusel, J. and Stierli, S. and Treier, M. and Studer, L. and Basler, K. and Levesque, M.P. and Dummer, R. and Santoro, R. and Cantù, C. and Sommer, L.
Nature Communications 12 (1): 5056. 20 August 2021

A simple pressure-assisted method for MicroED specimen preparation.
Zhao, J. and Xu, H. and Lebrette, H. and Carroni, M. and Taberman, H. and Högbom, M. and Zou, X.
Nature Communications 12 (1): 5036. 19 August 2021

Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.
Nouailles, G. and Wyler, E. and Pennitz, P. and Postmus, D. and Vladimirova, D. and Kazmierski, J. and Pott, F. and Dietert, K. and Muelleder, M. and Farztdinov, V. and Obermayer, B. and Wienhold, S.M. and Andreotti, S. and Hoefler, T. and Sawitzki, B. and Drosten, C. and Sander, L.E. and Suttorp, N. and Ralser, M. and Beule, D. and Gruber, A.D. and Goffinet, C. and Landthaler, M. and Trimpert, J. and Witzenrath, M.
Nature Communications 12 (1): 4869. 11 August 2021

M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
Breitkreuz-Korff, O. and Tscheik, C. and Del Vecchio, G. and Dithmer, S. and Walther, W. and Orthmann, A. and Wolburg, H. and Haseloff, R.F. and Schröder, L. and Blasig, I.E. and Winkler, L.
Journal of Controlled Release 330 : 137-148. 10 August 2021

Place fields of single spikes in hippocampus involve Kcnq3 channel-dependent entrainment of complex spike bursts.
Gao, X. and Bender, F. and Soh, H. and Chen, C. and Altafi, M. and Schütze, S. and Heidenreich, M. and Gorbati, M. and Corbu, M.A. and Carus-Cadavieco, M. and Korotkova, T. and Tzingounis, A.V. and Jentsch, T.J. and Ponomarenko, A.
Nature Communications 12 (1): 4801. 10 August 2021

Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders.
Duncan, A.R. and Polovitskaya, M.M. and Gaitán-Peñas, H. and Bertelli, S. and VanNoy, G.E. and Grant, P.E. and O'Donnell-Luria, A. and Valivullah, Z. and Lovgren, A.K. and England, E.M. and Agolini, E. and Madden, J.A. and Schmitz-Abe, K. and Kritzer, A. and Hawley, P. and Novelli, A. and Alfieri, P. and Colafati, G.S. and Wieczorek, D. and Platzer, K. and Luppe, J. and Koch-Hogrebe, M. and Abou Jamra, R. and Neira-Fresneda, J. and Lehman, A. and Boerkoel, C.F. and Seath, K. and Clarke, L. and van Ierland, Y. and Argilli, E. and Sherr, E.H. and Maiorana, A. and Diel, T. and Hempel, M. and Bierhals, T. and Estévez, R. and Jentsch, T.J. and Pusch, M. and Agrawal, P.B.
American Journal of Human Genetics 108 (8): 1450-1465. 5 August 2021

Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging.
Young, K. and Eudy, E. and Bell, R. and Loberg, M.A. and Stearns, T. and Sharma, D. and Velten, L. and Haas, S. and Filippi, M.D. and Trowbridge, J.J.
Cell Stem Cell 28 (8): 1473-1482. 5 August 2021

The continued need for animals to advance brain research.
Homberg, J.R. and Adan, R.A.H. and Alenina, N. and Asiminas, A. and Bader, M. and Beckers, T. and Begg, D.P. and Blokland, A. and Burger, M.E. and van Dijk, G. and Eisel, U.L.M. and Elgersma, Y. and Englitz, B. and Fernandez-Ruiz, A. and Fitzsimons, C.P. and van Dam, A.M. and Gass, P. and Grandjean, J. and Havekes, R. and Henckens, M.J.A.G. and Herden, C. and Hut, R.A. and Jarrett, W. and Jeffrey, K. and Jezova, D. and Kalsbeek, A. and Kamermans, M. and Kas, M.J. and Kasri, N.N. and Kiliaan, A.J. and Kolk, S.M. and Korosi, A. and Korte, S.M. and Kozicz, T. and Kushner, S.A. and Leech, K. and Lesch, K.P. and Lesscher, H. and Lucassen, P.J. and Luthi, A. and Ma, L. and Mallien, A.S. and Meerlo, P. and Mejias, J.F. and Meye, F.J. and Mitchell, A.S. and Mul, J.D. and Olcese, U. and González, A.O. and Olivier, J.D.A. and Pasqualetti, M. and Pennartz, C.M.A. and Popik, P. and Prickaerts, J. and de la Prida, L.M. and Ribeiro, S. and Roozendaal, B. and Rossato, J.I. and Salari, A.A. and Schoemaker, R.G. and Smit, A.B. and Vanderschuren, L.J.M.J. and Takeuchi, T. and van der Veen, R. and Smidt, M.P. and Vyazovskiy, V.V. and Wiesmann, M. and Wierenga, C.J. and Williams, B. and Willuhn, I. and Wöhr, M. and Wolvekamp, M. and van der Zee, E.A. and Genzel, L.
Neuron 109 (15): 2374-2379. 4 August 2021

Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.
Carley, L.N. and Mojica, J.P. and Wang, B. and Chen, C.Y. and Lin, Y.P. and Prasad, K.V.S.K and Chan, E. and Hsu, C.W. and Keith, R. and Nuñez, C.L. and Olson-Manning, C.F. and Rushworth, C.A. and Wagner, M.R. and Wang, J. and Yeh, P.M. and Reichelt, M. and Ghattas, K. and Gershenzon, J. and Lee, C.R. and Mitchell-Olds, T.
Nature Ecology & Evolution 5 : 1135-1144. August 2021

High-affinity T-cell receptor specific for MyD88 L265P mutation for adoptive T-cell therapy of B-cell malignancies.
Çınar, Ö. and Brzezicha, B. and Grunert, C. and Kloetzel, P.M. and Beier, C. and Peuker, C.A. and Keller, U. and Pezzutto, A. and Busse, A.
Journal for ImmunoTherapy of Cancer 9 (7): e002410. 30 July 2021

The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches.
Avancena, P. and Song, T. and Yao, Y. and Fehlner-Peach, H. and Diamond, B. and Gu, H. and Rajewsky, K. and Zou, Y.R.
Proceedings of the National Academy of Sciences of the United States of America 118 (30): e2100576118. 27 July 2021

Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Ganichkin, O.M. and Vancraenenbroeck, R. and Rosenblum, G. and Hofmann, H. and Mikhailov, A.S. and Daumke, O. and Noel, J.K.
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2101144118. 13 July 2021

Salt transiently inhibits mitochondrial energetics in mononuclear phagocytes.
Geisberger, S. and Bartolomaeus, H. and Neubert, P. and Willebrand, R. and Zasada, C. and Bartolomaeus, T. and McParland, V. and Swinnen, D. and Geuzens, A. and Maifeld, A. and Krampert, L. and Vogl, M. and Mähler, A. and Wilck, N. and Marko, L. and Tilic, E. and Forslund, S.K. and Binger, K.J. and Stegbauer, J. and Dechend, R. and Kleinewietfeld, M. and Jantsch, J. and Kempa, S. and Müller, D.N.
Circulation 144 (2): 144-158. 13 July 2021

Skin sodium is increased in male patients with multiple sclerosis and related animal models.
Huhn, K. and Linz, P. and Pemsel, F. and Michalke, B. and Seyferth, S. and Kopp, C. and Chaudri, M.A. and Rothhammer, V. and Dörfler, A. and Uder, M. and Nagel, A.M. and Müller, D.N. and Waschbisch, A. and Lee, D.H. and Bäuerle, T. and Linker, R.A. and Haase, S.
Proceedings of the National Academy of Sciences of the United States of America 118 (28): e2102549118. 13 July 2021

Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily.
Liu, J. and Tassinari, M. and Souza, D.P. and Naskar, S. and Noel, J.K. and Bohuszewicz, O. and Buck, M. and Williams, T.A. and Baum, B. and Low, H.H.
Cell 184 (14): 3660-3673. 8 July 2021

CTCF mediates dosage- and sequence-context-dependent transcriptional insulation by forming local chromatin domains.
Huang, H. and Zhu, Q. and Jussila, A. and Han, Y. and Bintu, B. and Kern, C. and Conte, M. and Zhang, Y. and Bianco, S. and Chiariello, A.M. and Yu, M. and Hu, R. and Tastemel, M. and Juric, I. and Hu, M. and Nicodemi, M. and Zhuang, X. and Ren, B.
Nature Genetics 53 (7): 1064-1074. July 2021

Simple sugar and sugar-sweetened beverage intake during adolescence and risk of colorectal cancer precursors: adolescent sugar intake and colorectal polyp.
Joh, H.K. and Lee, D.H. and Hur, J. and Nimptsch, K. and Chang, Y. and Joung, H. and Zhang, X. and Rezende, L.F.M. and Lee, J.E. and Ng, K. and Chen, Y. and Tabung, F.K. and Meyerhardt, J.A. and Chan, A.T. and Pischon, T. and Song, M. and Fuchs, C.S. and Willett, W.C. and Cao, Y. and Ogino, S. and Giovannucci, E. and Wu, K.
Gastroenterology 161 (1): 128-142. July 2021

CRISPR-based diagnostics.
Kaminski, M.M. and Abudayyeh, O.O. and Gootenberg, J.S. and Zhang, F. and Collins, J.J.
Nature Biomedical Engineering 5 (7): 643-656. July 2021

The rise of proteome-wide biophysics.
Mateus, A. and Savitski, M.M. and Piazza, I.
Molecular Systems Biology 17 (7): e10442. July 2021

A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.
Witte, F. and Ruiz-Orera, J. and Ciolli Mattioli, C. and Blachut, S. and Adami, E. and Schulz, J.F. and Schneider-Lunitz, V. and Hummel, O. and Patone, G. and Mücke, M.B. and Šilhavý, Jan and Heinig, M. and Bottolo, L. and Sanchis, D. and Vingron, M. and Chekulaeva, M. and Pravenec, M. and Hubner, N. and van Heesch, S.
Genome Biology 22 (1): 191. 28 June 2021

Post-myocardial infarction heart failure dysregulates the bone vascular niche.
Hoffmann, J. and Luxán, G. and Abplanalp, W.T. and Glaser, S.F. and Rasper, T. and Fischer, A. and Muhly-Reinholz, M. and Potente, M. and Assmus, B. and John, D. and Zeiher, A.M. and Dimmeler, S.
Nature Communications 12 (1): 3964. 25 June 2021

STEM pride: perspectives from transgender, nonbinary, and genderqueer scientists.
Armada-Moreira, A. and Cizauskas, C. and Fleury, G. and Forslund, S.K. and Guthman, E.M. and Hanafiah, A. and Hope, J.M. and Jayasinghe, I. and McSweeney, D. and Young, I.D.
Cell 184 (13): 3352-3355. 24 June 2021

Genome sequencing in myeloid cancers.
Dolnik, A. and Schrezenmeier, J. and Bullinger, L.
New England Journal of Medicine 384 (25): e106. 24 June 2021

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Gassen, N.C. and Papies, J. and Bajaj, T. and Emanuel, J. and Dethloff, F. and Chua, R.L. and Trimpert, J. and Heinemann, N. and Niemeyer, C. and Weege, F. and Hönzke, K. and Aschman, T. and Heinz, D.E. and Weckmann, K. and Ebert, T. and Zellner, A. and Lennarz, M. and Wyler, E. and Schroeder, S. and Richter, A. and Niemeyer, D. and Hoffmann, K. and Meyer, T.F. and Heppner, F.L. and Corman, V.M. and Landthaler, M. and Hocke, A.C. and Morkel, M. and Osterrieder, N. and Conrad, C. and Eils, R. and Radbruch, H. and Giavalisco, P. and Drosten, C. and Müller, M.A.
Nature Communications 12 (1): 3818. 21 June 2021

Dispersal strategies shape persistence and evolution of human gut bacteria.
Hildebrand, F. and Gossmann, T.I. and Frioux, C. and Özkurt, E. and Myers, P.N. and Ferretti, P. and Kuhn, M. and Bahram, M. and Nielsen, H.B. and Bork, P.
Cell Host & Microbe 29 (7): 1167-1176. 14 June 2021

GUNC: detection of chimerism and contamination in prokaryotic genomes.
Orakov, A. and Fullam, A. and Coelho, L.P. and Khedkar, S. and Szklarczyk, D. and Mende, D.R. and Schmidt, T.S.B. and Bork, P.
Genome Biology 22 (1): 178. 13 June 2021

Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories.
Friedrich, C. and Schallenberg, S. and Kirchner, M. and Ziehm, M. and Niquet, S. and Haji, M. and Beier, C. and Neudecker, J. and Klauschen, F. and Mertins, P.
Nature Communications 12 (1): 3576. 11 June 2021

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren, A.A. and Snellings, D.A. and Su, Y.S. and Hong, C.C. and Castro, M. and Tang, A.T. and Detter, M.R. and Hobson, N. and Girard, R. and Romanos, S. and Lightle, R. and Moore, T. and Shenkar, R. and Benavides, C. and Beaman, M.M. and Mueller-Fielitz, H. and Chen, M. and Mericko, P. and Yang, J. and Sung, D.C. and Lawton, M.T. and Ruppert, M. and Schwaninger, M. and Körbelin, J. and Potente, M. and Awad, I.A. and Marchuk, D.A. and Kahn, M.L.
Nature 594 (7862): :271-276. 10 June 2021

Swarm Learning for decentralized and confidential clinical machine learning.
Warnat-Herresthal, S. and Schultze, H. and Shastry, K.L. and Manamohan, S. and Mukherjee, S. and Garg, V. and Sarveswara, R. and Händler, K. and Pickkers, P. and Aziz, N.A. and Ktena, S. and Tran, F. and Bitzer, M. and Ossowski, S. and Casadei, N. and Herr, C. and Petersheim, D. and Behrends, U. and Kern, F. and Fehlmann, T. and Schommers, P. and Lehmann, C. and Augustin, M. and Rybniker, J. and Altmüller, J. and Mishra, N. and Bernardes, J.P. and Krämer, B. and Bonaguro, L. and Schulte-Schrepping, J. and De Domenico, E. and Siever, C. and Kraut, M. and Desai, M. and Monnet, B. and Saridaki, M. and Siegel, C.M. and Drews, A. and Nuesch-Germano, M. and Theis, H. and Heyckendorf, J. and Schreiber, S. and Kim-Hellmuth, S. and Nattermann, J. and Skowasch, D. and Kurth, I. and Keller, A. and Bals, R. and Nürnberg, P. and Rieß, O. and Rosenstiel, P. and Netea, M.G. and Theis, F. and Mukherjee, S. and Backes, M. and Aschenbrenner, A.C. and Ulas, T. and Breteler, M.M.B. and Giamarellos-Bourboulis, E.J. and Kox, M. and Becker, M. and Cheran, S. and Woodacre, M.S. and Goh, E.L. and Schultze, J.L.
Nature 594 (7862): 265-270. 10 June 2021

Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes.
Bathe-Peters, M. and Gmach, P. and Boltz, H.H. and Einsiedel, J. and Gotthardt, M. and Hübner, H. and Gmeiner, P. and Lohse, M.J. and Annibale, P.
Proceedings of the National Academy of Sciences of the United States of America 118 (23): e2101119118. 8 June 2021

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation.
Cuello, F. and Knaust, A.E. and Saleem, U. and Loos, M. and Raabe, J. and Mosqueira, D. and Laufer, S. and Schweizer, M. and Kraak, P. and Flenner, F. and Ulmer, B.M and Braren, I. and Yin, X. and Theofilatos, K. and Ruiz-Orera, J. and Patone, G. and Klampe, B. and Schulze, T. and Piasecki, A. and Pinto, Y. and Vink, A. and Hübner, N. and Harding, S. and Mayr, M. and Denning, C. and Eschenhagen, T. and Hansen, A.
EMBO Molecular Medicine 13 (6): e13074. 7 June 2021

Spatio-temporal mRNA tracking in the early zebrafish embryo.
Holler, K. and Neuschulz, A. and Drewe-Boß, P. and Mintcheva, J. and Spanjaard, B. and Arsiè, R. and Ohler, U. and Landthaler, M. and Junker, J.P.
Nature Communications 12 : 3358. 7 June 2021

Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Schmalbrock, L.K. and Dolnik, A. and Cocciardi, S. and Sträng, E. and Theis, F. and Jahn, N. and Panina, E. and Blätte, T.J. and Herzig, J.K. and Skambraks, S. and Rücker, F.G. and Gaidzik, V.I. and Paschka, P. and Fiedler, W. and Salih, H.R. and Wulf, G.G. and Schroeder, T. and Lübbert, M. and Schlenk, R.F. and Thol, F. and Heuser, M. and Larson, R.A. and Ganser, A. and Stunnenberg, H.G. and Minucci, S. and Stone, R.M. and Bloomfield, C.D. and Döhner, H. and Döhner, K. and Bullinger, L.
Blood 137 (22): 3093-3104. 3 June 2021

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network.
Grapotte, M. and Saraswat, M. and Bessière, C. and Menichelli, C. and Ramilowski, J.A. and Severin, J. and Hayashizaki, Y. and Itoh, M. and Tagami, M. and Murata, M. and Kojima-Ishiyama, M. and Noma, S. and Noguchi, S. and Kasukawa, T. and Hasegawa, A. and Suzuki, H. and Nishiyori-Sueki, H. and Frith, M.C. and Chatelain, C. and Carninci, P. and de Hoon, M.J.L. and Wasserman, W.W. and Bréhélin, L. and Lecellier, C.H.
Nature Communications 12 (1): 3297. 2 June 2021

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. and Grinat, J. and Kosel, F. and Liu, L. and Kunz, S. and Vidal, R.O. and Keil, M. and Haybaeck, J. and Robine, S. and Louvard, D. and Regenbrecht, C. and Sporbert, A. and Sauer, S. and von Eyss, B. and Sigal, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort.
Birukov, A. and Andersen, L.B. and Andersen, M.S. and Nielsen, J.H. and Nielsen, F.g and Kyhl, H.B. and Jørgensen, J.S. and Grandjean, P. and Dechend, R. and Jensen, T.K.
Environment International 151 : 106442. June 2021

Methodology of measuring postoperative cognitive dysfunction: a systematic review.
Borchers, F. and Spies, C.D. and Feinkohl, I. and Brockhaus, W.R. and Kraft, A. and Kozma, P. and Fislage, M. and Kühn, S. and Ionescu, C. and Speidel, S. and Hadzidiakos, D. and Veldhuijzen, D.S. and Yürek, F. and Evered, L.A. and Ottens, T.H.
British Journal of Anaesthesia 126 (6): 1119-1127. June 2021

Sodium and its manifold impact on our immune system.
Jobin, K. and Müller, D.N. and Jantsch, J. and Kurts, C.
Trends in Immunology 42 (6): 469-479. June 2021

PET-guided eBEACOPP treatment of advanced-stage Hodgkin lymphoma (HD18): follow-up analysis of an international, open-label, randomised, phase 3 trial.
Kreissl, S. and Goergen, H. and Buehnen, I. and Kobe, C. and Moccia, A. and Greil, R. and Eichenauer, D.A. and Zijlstra, J.M. and Markova, J. and Meissner, J. and Feuring-Buske, M. and Soekler, M. and Beck, H.J. and Willenbacher, W. and Ludwig, W.D. and Pabst, T. and Topp, M.S. and Hitz, F. and Bentz, M. and Keller, U.B. and Kühnhardt, D. and Ostermann, H. and Hertenstein, B. and Aulitzky, W. and Maschmeyer, G. and Vieler, T. and Eich, H. and Baues, C. and Stein, H. and Fuchs, M. and Diehl, V. and Dietlein, M. and Engert, A. and Borchmann, P.
Lancet Haematology 8 (6): e398-e409. June 2021

PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Garg, A. and Roske, Y. and Yamada, S. and Uehata, T. and Takeuchi, O. and Heinemann, U.
Nucleic Acids Research 49 (9): 5369-5381. 21 May 2021

Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Reimann, M. and Schrezenmeier, J.F. and Richter-Pechanska, P. and Dolnik, A. and Hick, T.P. and Schleich, K. and Cai, X. and Fan, D.N.Y. and Lohneis, P. and Masswig, S. and Denker, S. and Busse, A. and Knittel, G. and Flümann, R. and Childs, D. and Childs, L. and Gätjens-Sanchez, A.M. and Bullinger, L. and Rosenwald, A. and Reinhardt, H.C. and Schmitt, C.A.
Blood 137 (20): 2785-2899. 20 May 2021

Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin.
Mahn, M. and Saraf-Sinik, I. and Patil, P. and Pulin, M. and Bitton, E. and Karalis, N. and Bruentgens, F. and Palgi, S. and Gat, A. and Dine, J. and Wietek, J. and Davidi, I. and Levy, R. and Litvin, A. and Zhou, F. and Sauter, K. and Soba, P. and Schmitz, D. and Lüthi, A. and Rost, B.R. and Wiegert, J.S. and Yizhar, O.
Neuron 109 (10): 1621-1635. 19 May 2021

Reconstitution of β-adrenergic regulation of Ca(V)1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.
Katz, M. and Subramaniam, S. and Chomsky-Hecht, O. and Tsemakhovich, V. and Flockerzi, V. and Klussmann, E. and Hirsch, J.A. and Weiss, S. and Dascal, N.
Proceedings of the National Academy of Sciences of the United States of America 118 (21): e2100021118. 17 May 2021

Long-term effects of COVID-19 on kidney function.
Enghard, P. and Hardenberg, J.H. and Stockmann, H. and Hinze, C. and Eckardt, K.U. and Schmidt-Ott, K.M.
Lancet 397 (10287): 1806-1807. 15 May 2021

Systematic identification of A-to-I RNA editing in zebrafish development and adult organs.
Buchumenski, I. and Holler, K. and Appelbaum, L. and Eisenberg, E. and Junker, J.P. and Levanon, E.Y.
Nucleic Acids Research 49 (8): 4325-4337. 7 May 2021

DDX3 depletion represses translation of mRNAs with complex 5' UTRs.
Calviello, L. and Venkataramanan, S. and Rogowski, K.J. and Wyler, E. and Wilkins, K. and Tejura, M. and Thai, B. and Krol, J. and Filipowicz, W. and Landthaler, M. and Floor, S.N.
Nucleic Acids Research 49 (9): 5336-5350. May 2021

Comparison of the Hi-C, GAM and SPRITE methods using polymer models of chromatin.
Fiorillo, L. and Musella, F. and Conte, M. and Kempfer, R. and Chiariello, A.M. and Bianco, S. and Kukalev, A. and Irastorza-Azcarate, I. and Esposito, A. and Abraham, A. and Prisco, A. and Pombo, A. and Nicodemi, M.
Nature Methods 18 (5): 482-490. May 2021

Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder.
Griesi-Oliveira, K. and Fogo, M.S. and Pinto, B.G.G. and Alves, A.Y. and Suzuki, A.M. and Morales, A.G. and Ezquina, S. and Sosa, O.J. and Sutton, G.J. and Sunaga-Franze, D.Y. and Bueno, A.P. and Seabra, G. and Sardinha, L. and Costa, S.S. and Rosenberg, C. and Zachi, E.C. and Sertie, A.L. and Martins-de-Souza, D. and Reis, E.M. and Voineagu, I. and Passos-Bueno, M.R.
Molecular Psychiatry 26 (5): 1589-1605. May 2021

Assessing dysferlinopathy patients over three years with a new motor scale.
Jacobs, M. and James, M.K. and Lowes, L.P. and Alfano, L.N. and Eagle, M. and Lofra, R.M. and Moore, U. and Feng, J. and Rufibach, L.E. and Rose, K. and Duong, T. and Bello, L. and Pedrosa-Hernández, I. and Holsten, S. and Sakamoto, C. and Canal, A. and Práxedes, N.S.A. and Thiele, S. and Siener, C. and Vandevelde, B. and DeWolf, B. and Maron, E. and Guglieri, M. and Hogrel, J.Y. and Blamire, A.M. and Carlier, P.G. and Spuler, S. and Day, J.W. and Jones, K.J. and Bharucha-Goebel, D.X. and Salort-Campana, E. and Pestronk, A. and Walter, M.C. and Paradas, C. and Stojkovic, T. and Mori-Yoshimura, M. and Bravver, E. and Díaz-Manera, J. and Pegoraro, E. and Mendell, J.R. and Mayhew, A.G. and Straub, V.
Annals of Neurology 89 (5): 967-978. May 2021

Kidney physiology and susceptibility to acute kidney injury: implications for renoprotection.
Scholz, H. and Boivin, F.J. and Schmidt-Ott, K.M. and Bachmann, S. and Eckardt, K.U. and Scholl, U.I. and Persson, P.B.
Nature Reviews Nephrology 17 (5): 335-349. May 2021

Enhanced Ca(2+) signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1h(M1560V/+)).
Seidel, E. and Schewe, J. and Zhang, J. and Dinh, H.A. and Forslund, S.K. and Markó, L. and Hellmig, N. and Peters, J. and Muller, D.N. and Lifton, R.P. and Nottoli, T. and Stölting, G. and Scholl, U.I.
Proceedings of the National Academy of Sciences of the United States of America 118 (17): e2014876118. 27 April 2021

Epithelial response to IFN-γ promotes SARS-CoV-2 infection.
Heuberger, J. and Trimpert, J. and Vladimirova, D. and Goosmann, C. and Lin, M. and Schmuck, R. and Mollenkopf, H.J. and Brinkmann, V. and Tacke, F. and Osterrieder, N. and Sigal, M.
EMBO Molecular Medicine 13 (4): e13191. 9 April 2021

The gut microbiome in hypertension: recent advances and future perspectives.
Avery, E.G. and Bartolomaeus, H. and Maifeld, A. and Marko, L. and Wiig, H. and Wilck, N. and Rosshart, S.P. and Forslund, S.K. and Muller, D.N.
Circulation Research 128 (7): 934-950. 2 April 2021

Control of endothelial quiescence by FOXO-regulated metabolites.
Andrade, J. and Shi, C. and Costa, A.S.H. and Choi, J. and Kim, J. and Doddaballapur, A. and Sugino, T. and Ong, Y.T. and Castro, M. and Zimmermann, B. and Kaulich, M. and Guenther, S. and Wilhelm, K. and Kubota, Y. and Braun, T. and Koh, G.Y. and Grosso, A.R. and Frezza, C. and Potente, M.
Nature Cell Biology 23 : 413-423. April 2021

SNT: a unifying toolbox for quantification of neuronal anatomy.
Arshadi, C. and Günther, U. and Eddison, M. and Harrington, K.I.S. and Ferreira, T.A.
Nature Methods 18 : 374-377. April 2021

Astrocyte-derived Wnt growth factors are required for endothelial blood-brain barrier maintenance.
Guérit, S. and Fidan, E. and Macas, J. and Czupalla, C.J. and Figueiredo, R. and Vijikumar, A. and Yalcin, B.H. and Thom, S. and Winter, P. and Gerhardt, H. and Devraj, K. and Liebner, S.
Progress in Neurobiology 199 : 101937. April 2021

A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: results from the CONKO-005 trial.
Hoyer, K. and Hablesreiter, R. and Inoue, Y. and Yoshida, K. and Briest, F. and Christen, F. and Kakiuchi, N. and Yoshizato, T. and Shiozawa, Y. and Shiraishi, Y. and Striefler, J.K. and Bischoff, S. and Lohneis, P. and Putter, H. and Blau, O. and Keilholz, U. and Bullinger, L. and Pelzer, U. and Hummel, M. and Riess, H. and Ogawa, S. and Sinn, M. and Damm, F.
EBioMedicine 66 : 103327. April 2021

Knockout of aminopeptidase A in mice causes functional alterations and morphological glomerular basement membrane changes in the kidneys.
Marahrens, B. and Schulze, A. and Wysocki, J. and Lin, M.H. and Ye, M. and Kanwar, Y.S. and Bader, M. and Velez, J.C.Q. and Miner, J.H. and Batlle, D.
Kidney International 99 (4): 900-913. April 2021

YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer.
Quinn, H.M. and Vogel, R. and Popp, O. and Mertins, P. and Lan, L. and Messerschmidt, C. and Landshammer, A. and Lisek, K. and Château-Joubert, S. and Marangoni, E. and Koren, E. and Fuchs, Y. and Birchmeier, W.
Cancer Research 81 (8): 2116-2127. April 2021

High rates of long-term renal recovery in survivors of coronavirus disease 2019-associated acute kidney injury requiring kidney replacement therapy.
Stockmann, H. and Hardenberg, J.H.B. and Aigner, A. and Hinze, C. and Gotthardt, I. and Stier, B. and Eckardt, K.U. and Schmidt-Ott, K.M. and Enghard, P.
Kidney International 99 (4): 1021-1022. April 2021

Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients.
Maifeld, A. and Bartolomaeus, H. and Löber, U. and Avery, E.G. and Steckhan, N. and Markó, L. and Wilck, N. and Hamad, I. and Šušnjar, U. and Mähler, A. and Hohmann, C. and Chen, C.Y. and Cramer, H. and Dobos, G. and Lesker, T.R. and Strowig, T. and Dechend, R. and Bzdok, D. and Kleinewietfeld, M. and Michalsen, A. and Müller, D.N. and Forslund, S.K.
Nature Communications 12 (1): 1970. 30 March 2021

Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolbox.
Wirbel, J. and Zych, K. and Essex, M. and Karcher, N. and Kartal, E. and Salazar, G. and Bork, P. and Sunagawa, S. and Zeller, G.
Genome Biology 22 (1): 93. 30 March 2021

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Pentimalli, T.M. and Jüttner, R. and Glažar, P. and Uppal, K. and Bottani, E. and Brunetti, D. and Secker, C. and Zink, A. and Meierhofer, D. and Henke, M.T. and Dey, M. and Ciptasari, U. and Mlody, B. and Hahn, T. and Berruezo-Llacuna, M. and Karaiskos, N. and Di Virgilio, M. and Mayr, J.A. and Wortmann, S.B. and Priller, J. and Gotthardt, M. and Jones, D.P. and Mayatepek, E. and Stenzel, W. and Diecke, S. and Kühn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
Nature Communications 12 (1): 1929. 26 March 2021

Caveolin3 stabilizes McT1-mediated lactate/proton transport in cardiomyocytes.
Peper, J. and Kownatzki-Danger, D. and Weninger, G. and Seibertz, F. and Pronto, J.R. and Sutanto, H. and Pacheu Grau, D. and Hindmarsh, R. and Brandenburg, S. and Kohl, T. and Hasenfuβ, G. and Gotthardt, M. and Rog-Zielinska, E.A. and Wollnik, B. and Rehling, P. and Urlaub, H. and Wegener, J.W. and Heijman, J. and Voigt, N. and Cyganek, L. and Lenz, C. and Lehnart, S.E.
Circulation Research 128 (6): e102-e120. 19 March 2021

Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge.
Sieberts, S.K. and Schaff, J. and Duda, M. and Pataki, B.Á. and Sun, M. and Snyder, P. and Daneault, J.F. and Parisi, F. and Costante, G. and Rubin, U. and Banda, P. and Chae, Y. and Chaibub Neto, E. and Dorsey, E.R. and Aydın, Z. and Chen, A. and Elo, L.L. and Espino, C. and Glaab, E. and Goan, E. and Golabchi, F.N. and Görmez, Y. and Jaakkola, M.K. and Jonnagaddala, J. and Klén, R. and Li, D. and McDaniel, C. and Perrin, D. and Perumal, T.M. and Rad, N.M. and Rainaldi, E. and Sapienza, S. and Schwab, P. and Shokhirev, N. and Venäläinen, M.S. and Vergara-Diaz, G. and Zhang, Y. and Wang, Y. and Guan, Y. and Brunner, D. and Bonato, P. and Mangravite, L.M. and Omberg, L.
NPJ Digital Medicine 4 (1): 53. 19 March 2021

The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Heider, M. and Eichner, R. and Stroh, J. and Morath, V. and Kuisl, A. and Zecha, J. and Lawatscheck, J. and Baek, K. and Garz, A.K. and Rudelius, M. and Deuschle, F.C. and Keller, U. and Lemeer, S. and Verbeek, M. and Götze, K.S. and Skerra, A. and Weber, W.A. and Buchner, J. and Schulman, B.A. and Kuster, B. and Fernández-Sáiz, V. and Bassermann, F.
Molecular Cell 81 (6): 1170-1186. 18 March 2021

Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Nikolay, R. and Hilal, T. and Schmidt, S. and Qin, B. and Schwefel, D. and Vieira-Vieira, C.H. and Mielke, T. and Bürger, J. and Loerke, J. and Amikura, K. and Flügel, T. and Ueda, T. and Selbach, M. and Deuerling, E. and Spahn, C.M.T.
Molecular Cell 81 (6): 1200-1215. 18 March 2021

Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction.
Schiattarella, G.G. and Altamirano, F. and Kim, S.Y. and Tong, D. and Ferdous, A. and Piristine, H. and Dasgupta, S. and Wang, X. and French, K.M. and Villalobos, E. and Spurgin, S.B. and Waldman, M. and Jiang, N. and May, H.I. and Hill, T.M. and Luo, Y. and Yoo, H. and Zaha, V.G. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Nature Communications 12 (1): 1684. 16 March 2021

Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M. and Mikuda, N. and Höpken, U.E. and Kärgel, E. and Uyar, B. and Tufan, A.B. and Milanovic, M. and Sun, W. and Krahn, I. and Schleich, K. and von Hoff, L. and Hinz, M. and Willenbrock, M. and Jungmann, S. and Akalin, A. and Lee, S. and Schmidt-Ullrich, R. and Schmitt, C.A. and Scheidereit, C.
EMBO Journal 40 (6): e104296. 15 March 2021

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains.
Pluska, L. and Jarosch, E. and Zauber, H. and Kniss, A. and Waltho, A. and Bagola, K. and von Delbrück, M. and Löhr, F. and Schulman, B.A. and Selbach, M. and Dötsch, V. and Sommer, T.
EMBO Journal 40 (6): e106094. 15 March 2021

Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure.
Michalick, L. and Weidenfeld, S. and Grimmer, B. and Fatykhova, D. and Solymosi, P.D. and Behrens, F. and Dohmen, M. and Brack, M.C. and Schulz, S. and Thomasch, E. and Simmons, S. and Müller-Redetzky, H. and Suttorp, N. and Kurth, F. and Neudecker, J. and Toennies, M. and Bauer, T.T. and Eggeling, S. and Corman, V.M. and Hocke, A.C. and Witzenrath, M. and Hippenstiel, S. and Kuebler, W.M.
European Respiratory Journal 57 (3): 2002384. 11 March 2021

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Muus, C. and Luecken, M.D. and Eraslan, G. and Sikkema, L. and Waghray, A. and Heimberg, G. and Kobayashi, Y. and Vaishnav, E.D. and Subramanian, A. and Smillie, C. and Jagadeesh, K.A. and Duong, E.T. and Fiskin, E. and Triglia, E.T. and Ansari, M. and Cai, P. and Lin, B. and Buchanan, J. and Chen, S. and Shu, J. and Haber, A.L. and Chung, H. and Montoro, D.T. and Adams, T. and Aliee, H. and Allon, S.J. and Andrusivova, Z. and Angelidis, I. and Ashenberg, O. and Bassler, K. and Bécavin, C. and Benhar, I. and Bergenstråhle, J. and Bergenstråhle, L. and Bolt, L. and Braun, E. and Bui, L.T. and Callori, S. and Chaffin, M. and Chichelnitskiy, E. and Chiou, J. and Conlon, T.M. and Cuoco, M.S. and Cuomo, A.S.E. and Deprez, M. and Duclos, G. and Fine, D. and Fischer, D.S. and Ghazanfar, S. and Gillich, A. and Giotti, B. and Gould, J. and Guo, M. and Gutierrez, A.J. and Habermann, A.C. and Harvey, T. and He, P. and Hou, X. and Hu, L. and Hu, Y. and Jaiswal, A. and Ji, L. and Jiang, P. and Kapellos, T.S. and Kuo, C.S. and Larsson, L. and Leney-Greene, M.A. and Lim, K. and Litviňuková, M. and Ludwig, L.S. and Lukassen, S. and Luo, W. and Maatz, H. and Madissoon, E. and Mamanova, L. and Manakongtreecheep, K. and Leroy, S. and Mayr, C.H. and Mbano, I.M. and McAdams, A.M. and Nabhan, A.N. and Nyquist, S.K. and Penland, L. and Poirion, O.B. and Poli, S. and Qi, C.C. and Queen, R. and Reichart, D. and Rosas, I. and Schupp, J.C. and Shea, C.V. and Shi, X. and Sinha, R. and Sit, R.V. and Slowikowski, K. and Slyper, M. and Smith, N.P. and Sountoulidis, A. and Strunz, M. and Sullivan, T.B. and Sun, D. and Talavera-López, C. and Tan, P. and Tantivit, J. and Travaglini, K.J. and Tucker, N.R. and Vernon, K.A. and Wadsworth, M.H. and Waldman, J. and Wang, X. and Xu, K. and Yan, W. and Zhao, W. and Ziegler, C.G.K.
Nature Medicine 27 (3): 546-559. 2 March 2021

Quantifying technical confounders in microbiome studies.
Bartolomaeus, T.U.P. and Birkner, T. and Bartolomaeus, H. and Löber, U. and Avery, E.G. and Mähler, A. and Weber, D. and Kochlik, B. and Balogh, A. and Wilck, N. and Boschmann, M. and Müller, D.N. and Markó, L. and Forslund, S.K.
Cardiovascular Research 117 (3): 863-875. 1 March 2021

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Velten, L. and Story, B.A. and Hernández-Malmierca, P. and Raffel, S. and Leonce, D.R. and Milbank, J. and Paulsen, M. and Demir, A. and Szu-Tu, C. and Frömel, R. and Lutz, C. and Nowak, D. and Jann, J.C. and Pabst, C. and Boch, T. and Hofmann, W.K. and Müller-Tidow, C. and Trumpp, A. and Haas, S. and Steinmetz, L.M.
Nature Communications 12 (1): 1366. 1 March 2021

Reactive astrocyte nomenclature, definitions, and future directions.
Escartin, C. and Galea, E. and Lakatos, A. and O'Callaghan, J.P. and Petzold, G.C. and Serrano-Pozo, A. and Steinhäuser, C. and Volterra, A. and Carmignoto, G. and Agarwal, A. and Allen, N.J. and Araque, A. and Barbeito, L. and Barzilai, A. and Bergles, D.E. and Bonvento, G. and Butt, A.M. and Chen, W.T. and Cohen-Salmon, M. and Cunningham, C. and Deneen, B. and De Strooper, B. and Díaz-Castro, B. and Farina, C. and Freeman, M. and Gallo, V. and Goldman, J.E. and Goldman, S.A. and Götz, M. and Gutiérrez, A. and Haydon, P.G. and Heiland, D.H. and Hol, E.M. and Holt, M.G. and Iino, M. and Kastanenka, K.V. and Kettenmann, H. and Khakh, B.S. and Koizumi, S. and Lee, C.J. and Liddelow, S.A. and MacVicar, B.A. and Magistretti, P. and Messing, A. and Mishra, A. and Molofsky, A.V. and Murai, K.K. and Norris, C.M. and Okada, S. and Oliet, S.H.R. and Oliveira, J.F. and Panatier, A. and Parpura, V. and Pekna, M. and Pekny, M. and Pellerin, L. and Perea, G. and Pérez-Nievas, B.G. and Pfrieger, F.W. and Poskanzer, K.E. and Quintana, F.J. and Ransohoff, R.M. and Riquelme-Perez, M. and Robel, S. and Rose, C.R. and Rothstein, J.D. and Rouach, N. and Rowitch, D.H. and Semyanov, A. and Sirko, S. and Sontheimer, H. and Swanson, R.A. and Vitorica, J. and Wanner, I.B. and Wood, L.B. and Wu, J. and Zheng, B. and Zimmer, E.R. and Zorec, R. and Sofroniew, M.V. and Verkhratsky, A.
Nature Neuroscience 24 (3): 312-325. March 2021

Determination of G-protein-coupled receptor oligomerization by molecular brightness analyses in single cells.
Işbilir, A. and Serfling, R. and Möller, J. and Thomas, R. and De Faveri, C. and Zabel, U. and Scarselli, M. and Beck-Sickinger, A.G. and Bock, A. and Coin, I. and Lohse, M.J. and Annibale, P.
Nature Protocols 16 (3): 1419-1451. March 2021

Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma.
Roeschert, I. and Poon, E. and Henssen, A.G. and Dorado Garcia, H. and Gatti, M. and Giansanti, C. and Jamin, Y. and Ade, C.P. and Gallant, P. and Schülein-Völk, C. and Beli, P. and Richards, M. and Rosenfeldt, M. and Altmeyer, M. and Anderson, J. and Eggert, A. and Dobbelstein, M. and Bayliss, R. and Chesler, L. and Büchel, G. and Eilers, M.
Nature Cancer 2 (3): 312-326. March 2021

Charting a DNA repair roadmap for immunoglobulin class switch recombination.
Saha, T. and Sundaravinayagam, D. and Di Virgilio, M.
Trends in Biochemical Sciences 46 (3): 184-199. March 2021

Phenotypic mapping of pathologic cross-talk between glioblastoma and innate immune cells by synthetic genetic tracing.
Schmitt, M.J. and Company, C. and Dramaretska, Y. and Barozzi, I. and Göhrig, A. and Kertalli, S. and Großmann, M. and Naumann, H. and Sánchez-Bailón, M.P. and Hulsman, D. and Glass, R. and Squatrito, M. and Serresi, M. and Gargiulo, G.
Cancer Discovery 11 (3): 754-777. March 2021

Myocarditis and inflammatory cardiomyopathy: current evidence and future directions.
Tschöpe, C. and Ammirati, E. and Bozkurt, B. and Caforio, A.L.P. and Cooper, L.T. and Felix, S.B. and Hare, J.M. and Heidecker, B. and Heymans, S. and Hübner, N. and Kelle, S. and Klingel, K. and Maatz, H. and Parwani, A.S. and Spillmann, F. and Starling, R.C. and Tsutsui, H. and Seferovic, P. and Van Linthout, S.
Nature Reviews Cardiology 18 (3): 169-193. March 2021

Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant.
Jiang, H. and Hooper, C. and Kelly, M. and Steeples, V. and Simon, J.N. and Beglov, J. and Azad, A.J. and Leinhos, L. and Bennett, P. and Ehler, E. and Kalisch-Smith, J.I. and Sparrow, D.B. and Fischer, R. and Heilig, R. and Isackson, H. and Ehsan, M. and Patone, G. and Huebner, N. and Davies, B. and Watkins, H. and Gehmlich, K.
Basic Research in Cardiology 116 (1): 14. 26 February 2021

The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M. and Farré i Díaz, C. and Ofenbauer, A. and Herzog, S. and Tursun, B.
Nucleic Acids Research 49 (4): e22. 26 February 2021

CoBold: a method for identifying different functional classes of transient RNA structure features that can impact RNA structure formation in vivo.
Martín, A.L. and Mounir, M. and Meyer, I.M.
Nucleic Acids Research 49 (4): e19. 26 February 2021

Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells.
Zhang, Y. and Lahmann, I. and Baum, K. and Shimojo, H. and Mourikis, P. and Wolf, J. and Kageyama, R. and Birchmeier, C.
Nature Communications 12 (1): 1318. 26 February 2021

Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A. and Sieverling, L. and Nadler-Holly, M. and Ziehm, M. and Toprak, U.H. and Herrmann, C. and Ishaque, N. and Okonechnikov, K. and Gartlgruber, M. and Park, Y.G. and Wecht, E.M. and Savelyeva, L. and Henrich, K.O. and Rosswog, C. and Fischer, M. and Hero, B. and Jones, D.T.W. and Pfaff, E. and Witt, O. and Pfister, S.M. and Volckmann, Ri. and Koster, J. and Kiesel, K. and Rippe, K. and Taschner-Mandl, S. and Ambros, P. and Brors, B. and Selbach, M. and Feuerbach, L. and Westermann, F.
Nature Communications 12 (1): 1269. 24 February 2021

Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition.
Serresi, M. and Kertalli, S. and Li, L. and Schmitt, M.J. and Dramaretska, Y. and Wierikx, J. and Hulsman, D. and Gargiulo, G.
Science Advances 7 (9): eabd7974. 24 February 2021

Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.
Worpenberg, L. and Paolantoni, C. and Longhi, S. and Mulorz, M.M. and Lence, T. and Wessels, H.H. and Dassi, E. and Aiello, G. and Sutandy, F.X.R. and Scheibe, M. and Edupuganti, R.R. and Busch, A. and Möckel, M.M. and Vermeulen, M. and Butter, F. and König, J. and Notarangelo, M. and Ohler, U. and Dieterich, C. and Quattrone, A. and Soldano, A. and Roignant, J.Y.
EMBO Journal 40 (4): e104975. 15 February 2021

Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Iftekhar, A. and Berger, H. and Bouznad, N. and Heuberger, J. and Boccellato, F. and Dobrindt, U. and Hermeking, H. and Sigal, M. and Meyer, T.F.
Nature Communications 12 (1): 1003. 12 February 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky, D.J. and Abdel-Aziz, A.K. and Abdelfatah, S. and Abdellatif, M. and Abdoli, A. and Abel, S. and Abeliovich, H. and Abildgaard, M.H. and Abudu, Y.P. and Acevedo-Arozena, A. and Adamopoulos, I.E. and Adeli, K. and Adolph, T.E. and Adornetto, A. and Aflaki, E. and Agam, G. and Agarwal, A. and Aggarwal, B.B. and Agnello, M. and Agostinis, P. and Agrewala, J.N. and Agrotis, A. and Aguilar, P.V. and Ahmad, S.T. and Ahmed, Z.M. and Ahumada-Castro, U. and Aits, S. and Aizawa, S. and Akkoc, Y. and Akoumianaki, T. and Akpinar, H.A. and Al-Abd, A.M. and Al-Akra, L. and Al-Gharaibeh, A. and Alaoui-Jamali, M.A. and Alberti, S. and Alcocer-Gómez, E. and Alessandri, C. and Ali, M. and Alim Al-Bari, M.A. and Aliwaini, S. and Alizadeh, J. and Almacellas, E. and Almasan, A. and Alonso, A. and Alonso, G.D. and Altan-Bonnet, N. and Altieri, D.C. and Álvarez, E.M.C. and Alves, S. and Alves da Costa, C. and Alzaharna, M.M. and Amadio, M. and Amantini, C. and Amaral, C. and Ambrosio, S. and Amer, A.O. and Ammanathan, V. and An, Z. and Andersen, S.U. and Andrabi, S.A. and Andrade-Silva, M. and Andres, A.M. and Angelini, S. and Ann, D. and Anozie, U.C. and Ansari, M.Y. and Antas, P. and Antebi, A. and Antón, Z. and Anwar, T. and Apetoh, L. and Apostolova, N. and Araki, T. and Araki, Y. and Arasaki, K. and Araújo, W.L. and Araya, J. and Arden, C. and Arévalo, M.A. and Arguelles, S. and Arias, E. and Arikkath, J. and Arimoto, H. and Ariosa, A.R. and Armstrong-James, D. and Arnauné-Pelloquin, L. and Aroca, A. and Arroyo, D.S. and Arsov, I. and Artero, R. and Asaro, D.M.L. and Aschner, M. and Ashrafizadeh, M. and Ashur-Fabian, O. and Atanasov, A.G. and Au, A.K. and Auberger, P. and Auner, H.W. and Aurelian, L. and Autelli, R. and Avagliano, L. and Ávalos, Y. and Aveic, S. and Aveleira, C.A. and Avin-Wittenberg, T. and Aydin, Y. and Ayton, S. and Ayyadevara, S. and Azzopardi, M. and Baba, M.u and Backer, J.M. and Backues, S.K. and Bae, D.H. and Bae, O.N. and Bae, S.H. and Baehrecke, E.H. and Baek, A. and Baek, S.H. and Baek, S.H. and Bagetta, G. and Bagniewska-Zadworna, A. and Bai, H. and Bai, J. and Bai, X. and Bai, Y. and Bairagi, N. and Baksi, S. and Balbi, T. and Baldari, C.T. and Balduini, W. and Ballabio, A. and Ballester, M. and Balazadeh, S. and Balzan, R. and Bandopadhyay, R. and Banerjee, S. and Banerjee, S. and Bánréti, A. and Bao, Y. and Baptista, M.S. and Baracca, A. and Barbati, C. and Bargiela, A. and Barilà, D. and Barlow, P.G. and Barmada, S.J. and Barreiro, E. and Barreto, G.E. and Bartek, J. and Bartel, B. and Bartolome, A. and Barve, G.R. and Basagoudanavar, S.H. and Bassham, D.C. and Bast, R.C. and Basu, A. and Batoko, H. and Batten, I. and Baulieu, E.E. and Baumgarner, B.L. and Bayry, J. and Beale, R. and Beau, I. and Beaumatin, F. and Bechara, L.R.G. and Beck, G.R. and Beers, M.F. and Begun, J. and Behrends, C. and Behrens, G.M.N. and Bei, R. and Bejarano, E. and Bel, S. and Behl, C. and Belaid, A. and Belgareh-Touzé, N. and Bellarosa, C. and Belleudi, F. and Belló Pérez, M. and Bello-Morales, R. and Beltran, J.S.O. and Beltran, S. and Benbrook, D.M. and Bendorius, M. and Benitez, B.A. and Benito-Cuesta, I. and Bensalem, J. and Berchtold, M.W. and Berezowska, S. and Bergamaschi, D. and Bergami, M. and Bergmann, A. and Berliocchi, L. and Berlioz-Torrent, C. and Bernard, A. and Berthoux, L. and Besirli, C.G. and Besteiro, S. and Betin, V.M. and Beyaert, R. and Bezbradica, J.S. and Bhaskar, K. and Bhatia-Kissova, I. and Bhattacharya, R. and Bhattacharya, S. and Bhattacharyya, S. and Bhuiyan, M.S. and Bhutia, S.K. and Bi, L. and Bi, X. and Biden, T.J. and Bijian, K. and Billes, V.A. and Binart, N. and Bincoletto, C. and Birgisdottir, A.B. and Bjorkoy, G. and Blanco, G. and Blas-Garcia, A. and Blasiak, J. and Blomgran, R. and Blomgren, K. and Blum, J.S. and Boada-Romero, E. and Boban, M. and Boesze-Battaglia, K. and Boeuf, P. and Boland, B. and Bomont, P. and Bonaldo, P. and Bonam, S.R. and Bonfili, L. and Bonifacino, J.S. and Boone, B.A. and Bootman, M.D. and Bordi, M. and Borner, C. and Bornhauser, B.C. and Borthakur, G. and Bosch, J. and Bose, S. and Botana, L.M. and Botas, J. and Boulanger, C.M. and Boulton, M.E. and Bourdenx, M. and Bourgeois, B. and Bourke, N.M. and Bousquet, G. and Boya, P. and Bozhkov, P.V. and Bozi, L.H.M. and Bozkurt, T.O. and Brackney, D.E. and Brandts, C.H. and Braun, R.J. and Braus, G.H. and Bravo-Sagua, R. and Bravo-San Pedro, J.M. and Brest, P. and Bringer, M.A. and Briones-Herrera, A. and Broaddus, V.C. and Brodersen, P. and Brodsky, J.L. and Brody, S.L. and Bronson, P.G. and Bronstein, J.M. and Brown, C.N. and Brown, R.E. and Brum, P.C. and Brumell, J.H. and Brunetti-Pierri, N. and Bruno, D. and Bryson-Richardson, R.J. and Bucci, C. and Buchrieser, C. and Bueno, M. and Buitrago-Molina, L.E. and Buraschi, S. and Buch, S. and Buchan, J.R. and Buckingham, E.M. and Budak, H. and Budini, M. and Bultynck, G. and Burada, F. and Burgoyne, J.R. and Burón, M.I. and Bustos, V. and Büttner, S. and Butturini, E. and Byrd, A. and Cabas, I. and Cabrera-Benitez, S. and Cadwell, K. and Cai, J. and Cai, L. and Cai, Q. and Cairó, M. and Calbet, J.A. and Caldwell, G.A. and Caldwell, K.A. and Call, J.A. and Calvani, R. and Calvo, A.C. and Calvo-Rubio Barrera, M. and Camara, N.O. and Camonis, J.H. and Camougrand, N. and Campanella, M. and Campbell, E.M. and Campbell-Valois, F.X. and Campello, S. and Campesi, I. and Campos, J.C. and Camuzard, O. and Cancino, J. and Candido de Almeida, D. and Canesi, L. and Caniggia, I. and Canonico, B. and Cantí, C. and Cao, B. and Caraglia, M. and Caramés, B. and Carchman, E.H. and Cardenal-Muñoz, E. and Cardenas, C. and Cardenas, L. and Cardoso, S.M. and Carew, J.S. and Carle, G.F. and Carleton, G. and Carloni, S. and Carmona-Gutierrez, D. and Carneiro, L.A. and Carnevali, O. and Carosi, J.M. and Carra, S. and Carrier, A. and Carrier, L. and Carroll, B. and Carter, A.B. and Carvalho, A.N. and Casanova, M. and Casas, C. and Casas, J. and Cassioli, C. and Castillo, E.F. and Castillo, K. and Castillo-Lluva, S. and Castoldi, F. and Castori, M. and Castro, A.F. and Castro-Caldas, M. and Castro-Hernandez, J. and Castro-Obregon, S. and Catz, S.D. and Cavadas, C. and Cavaliere, F. and Cavallini, G. and Cavinato, M. and Cayuela, M.L. and Cebollada Rica, P. and Cecarini, V. and Cecconi, F. and Cechowska-Pasko, M. and Cenci, S. and Ceperuelo-Mallafré, V. and Cerqueira, J.J. and Cerutti, J.M. and Cervia, D. and Cetintas, V.B. and Cetrullo, S. and Chae, H.J. and Chagin, A.S. and Chai, C.Y. and Chakrabarti, G. and Chakrabarti, O. and Chakraborty, T. and Chakraborty, T. and Chami, M. and Chamilos, G. and Chan, D.W. and Chan, E.Y.W. and Chan, E.D. and Chan, H.Y.E. and Chan, H.H. and Chan, H. and Chan, M.T.V. and Chan, Y.S. and Chandra, P.K. and Chang, C.P. and Chang, C. and Chang, H.C. and Chang, K. and Chao, J. and Chapman, T. and Charlet-Berguerand, N. and Chatterjee, S. and Chaube, S.K. and Chaudhary, A. and Chauhan, S. and Chaum, E. and Checler, F. and Cheetham, M.E. and Chen, C.S. and Chen, G.C. and Chen, J.F. and Chen, L.L. and Chen, L. and Chen, L. and Chen, M. and Chen, M.K. and Chen, N. and Chen, Q. and Chen, R.H. and Chen, S. and Chen, W. and Chen, W. and Chen, X.M. and Chen, X.W. and Chen, X. and Chen, Y. and Chen, Y.G. and Chen, Y. and Chen, Y. and Chen, Y.J. and Chen, Y.Q. and Chen, Z.S. and Chen, Z. and Chen, Z.H. and Chen, Z.J. and Chen, Z. and Cheng, H. and Cheng, J. and Cheng, S.Y. and Cheng, W. and Cheng, X. and Cheng, X.T. and Cheng, Y. and Cheng, Z. and Chen, Z. and Cheong, H. and Cheong, J.K. and Chernyak, B.V. and Cherry, S. and Cheung, C.F.R. and Cheung, C.H.A. and Cheung, K.H. and Chevet, E. and Chi, R.J. and Chiang, A.K.S. and Chiaradonna, F. and Chiarelli, R. and Chiariello, M. and Chica, N. and Chiocca, S. and Chiong, M. and Chiou, S.H. and Chiramel, A.I. and Chiurchiù, V. and Cho, D.H. and Choe, S.K. and Choi, A.M.K. and Choi, M.E. and Choudhury, K.R. and Chow, N.S. and Chu, C.T. and Chua, J.P. and Chua, J.J.E. and Chung, H. and Chung, K.P. and Chung, S. and Chung, S.H. and Chung, Y.L. and Cianfanelli, V. and Ciechomska, I.A. and Cifuentes, M. and Cinque, L. and Cirak, S. and Cirone, M. and Clague, M.J. and Clarke, R. and Clementi, E. and Coccia, E.M. and Codogno, P. and Cohen, E. and Cohen, M.M and Colasanti, T. and Colasuonno, F. and Colbert, R.A. and Colell, A. and Čolić, M. and Coll, N.S. and Collins, M.O. and Colombo, M.I. and Colón-Ramos, D.A. and Combaret, L. and Comincini, S. and Cominetti, M.R. and Consiglio, A. and Conte, A. and Conti, F. and Contu, V.R. and Cookson, M.R. and Coombs, K.M. and Coppens, I. and Corasaniti, M.T. and Corkery, D.P. and Cordes, N. and Cortese, K. and Costa, M.D.C. and Costantino, S. and Costelli, P. and Coto-Montes, A. and Crack, P.J. and Crespo, J.L. and Criollo, A. and Crippa, V. and Cristofani, R. and Csizmadia, T. and Cuadrado, A. and Cui, B. and Cui, J. and Cui, Y. and Cui, Y. and Culetto, E. and Cumino, A.C. and Cybulsky, A.V. and Czaja, M.J. and Czuczwar, S.J. and D'Adamo, S. and D'Amelio, M. and D'Arcangelo, D. and D'Lugos, A.C. and D'Orazi, G. and da Silva, J.A. and Dafsari, H.S. and Dagda, R.K. and Dagdas, Y. and Daglia, M. and Dai, X. and Dai, Y. and Dai, Y. and Dal Col, J. and Dalhaimer, P. and Dalla Valle, L. and Dallenga, T. and Dalmasso, G. and Damme, M. and Dando, I. and Dantuma, N.P. and Darling, A.L. and Das, H. and Dasarathy, S. and Dasari, S.K. and Dash, S. and Daumke, O. and Dauphinee, A.N. and Davies, J.S. and Dávila, V.A. and Davis, R.J. and Davis, T. and Dayalan Naidu, S. and De Amicis, F. and De Bosscher, K. and De Felice, F. and De Franceschi, L. and De Leonibus, C. and de Mattos Barbosa, M.G. and De Meyer, G.R.Y. and De Milito, A. and De Nunzio, C. and De Palma, C. and De Santi, M. and De Virgilio, C. and De Zio, D. and Debnath, J. and DeBosch, B.J. and Decuypere, J.P. and Deehan, M.A. and Deflorian, G. and DeGregori, J. and Dehay, B. and Del Rio, G. and Delaney, J.R. and Delbridge, L.M.D. and Delorme-Axford, E. and Delpino, M.V. and Demarchi, F. and Dembitz, V. and Demers, N.D. and Deng, H. and Deng, Z. and Dengjel, J. and Dent, P. and Denton, D. and DePamphilis, M.L. and Der, C.J. and Deretic, V. and Descoteaux, A. and Devis, L. and Devkota, S. and Devuyst, O. and Dewson, G. and Dharmasivam, M. and Dhiman, R. and di Bernardo, D. and Di Cristina, M. and Di Domenico, F. and Di Fazio, P. and Di Fonzo, A. and Di Guardo, G. and Di Guglielmo, G.M. and Di Leo, L. and Di Malta, C. and Di Nardo, A. and Di Rienzo, M. and Di Sano, F. and Diallinas, G. and Diao, J. and Diaz-Araya, G. and Díaz-Laviada, I. and Dickinson, J.M. and Diederich, M. and Dieudé, M. and Dikic, I. and Ding, S. and Ding, W.X. and Dini, L. and Dinić, J. and Dinic, M. and Dinkova-Kostova, A.T. and Dionne, M.S. and Distler, J.H.W. and Diwan, A. and Dixon, I.M.C. and Djavaheri-Mergny, M. and Dobrinski, I. and Dobrovinskaya, O. and Dobrowolski, R. and Dobson, R.C.J. and Đokić, J. and Dokmeci Emre, S. and Donadelli, M. and Dong, B. and Dong, X. and Dong, Z. and Dorn Ii, G.W. and Dotsch, V. and Dou, H. and Dou, J. and Dowaidar, M. and Dridi, S. and Drucker, L. and Du, A. and Du, C. and Du, G. and Du, H.N. and Du, L.L. and du Toit, A. and Duan, S.B. and Duan, X. and Duarte, S.P. and Dubrovska, A. and Dunlop, E.A. and Dupont, N. and Durán, R.V. and Dwarakanath, B.S. and Dyshlovoy, S.A. and Ebrahimi-Fakhari, D. and Eckhart, L. and Edelstein, C.L. and Efferth, T. and Eftekharpour, E. and Eichinger, L. and Eid, N. and Eisenberg, T. and Eissa, N.T. and Eissa, S. and Ejarque, M. and El Andaloussi, A. and El-Hage, N. and El-Naggar, S. and Eleuteri, A.M. and El-Shafey, E.S. and Elgendy, M. and Eliopoulos, A.G. and Elizalde, M.M. and Elks, P.M. and Elsasser, H.P. and Elsherbiny, E.S. and Emerling, B.M. and Emre, N.C.T. and Eng, C.H. and Engedal, N. and Engelbrecht, A.M. and Engelsen, A.S.T. and Enserink, J.M. and Escalante, R. and Esclatine, A. and Escobar-Henriques, M. and Eskelinen, E.L. and Espert, L. and Eusebio, M.O. and Fabrias, G. and Fabrizi, C. and Facchiano, A. and Facchiano, F. and Fadeel, B. and Fader, C. and Faesen, A.C. and Fairlie, W.D. and Falcó, A. and Falkenburger, B.H. and Fan, D. and Fan, J. and Fan, Y. and Fang, E.F. and Fang, Y. and Fang, Y. and Fanto, M. and Farfel-Becker, T. and Faure, M. and Fazeli, G. and Fedele, A.O. and Feldman, A.M. and Feng, D. and Feng, J. and Feng, L. and Feng, Y. and Feng, Y. and Feng, W. and Fenz Araujo, T. and Ferguson, T.A. and Fernández, A.F. and Fernandez-Checa, J.C. and Fernández-Veledo, S. and Fernie, A.R. and Ferrante, A.W. and Ferraresi, A. and Ferrari, M.F. and Ferreira, J.C.B. and Ferro-Novick, S. and Figueras, A. and Filadi, R. and Filigheddu, N. and Filippi-Chiela, E. and Filomeni, G. and Fimia, G.M. and Fineschi, V. and Finetti, F. and Finkbeiner, S. and Fisher, E.A. and Fisher, P.B. and Flamigni, F. and Fliesler, S.J. and Flo, T.H. and Florance, I. and Florey, O. and Florio, T. and Fodor, E. and Follo, C. and Fon, E.A. and Forlino, A. and Fornai, F. and Fortini, P. and Fracassi, A. and Fraldi, A. and Franco, B. and Franco, R. and Franconi, F. and Frankel, L.B. and Friedman, S.L. and Fröhlich, L.F. and Frühbeck, G. and Fuentes, J.M. and Fujiki, Y. and Fujita, N. and Fujiwara, Y. and Fukuda, M. and Fulda, S. and Furic, L. and Furuya, N. and Fusco, C. and Gack, M.U. and Gaffke, L. and Galadari, S. and Galasso, A. and Galindo, M.F. and Gallolu Kankanamalage, S. and Galluzzi, L. and Galy, V. and Gammoh, N. and Gan, B. and Ganley, I.G. and Gao, F. and Gao, H. and Gao, M. and Gao, P. and Gao, S.J. and Gao, W. and Gao, X. and Garcera, A. and Garcia, M.N. and Garcia, V.E. and García-Del Portillo, F. and Garcia-Escudero, V. and Garcia-Garcia, A. and Garcia-Macia, M. and García-Moreno, D. and Garcia-Ruiz, C. and García-Sanz, P. and Garg, A.D. and Gargini, R. and Garofalo, T. and Garry, R.F. and Gassen, N.C. and Gatica, D. and Ge, L. and Ge, W. and Geiss-Friedlander, R. and Gelfi, C. and Genschik, P. and Gentle, I.E. and Gerbino, V. and Gerhardt, C. and Germain, K. and Germain, M. and Gewirtz, D.A. and Ghasemipour Afshar, E. and Ghavami, S. and Ghigo, A. and Ghosh, M. and Giamas, G. and Giampietri, C. and Giatromanolaki, A. and Gibson, G.E. and Gibson, S.B. and Ginet, V. and Giniger, E. and Giorgi, C. and Girao, H. and Girardin, S.E. and Giridharan, M. and Giuliano, S. and Giulivi, C. and Giuriato, S. and Giustiniani, J. and Gluschko, A. and Goder, V. and Goginashvili, A. and Golab, J. and Goldstone, D.C. and Golebiewska, A. and Gomes, L.R. and Gomez, R. and Gómez-Sánchez, R. and Gomez-Puerto, M.C. and Gomez-Sintes, R. and Gong, Q. and Goni, F.M. and González-Gallego, J. and Gonzalez-Hernandez, T. and Gonzalez-Polo, R.A. and Gonzalez-Reyes, J.A. and González-Rodríguez, P. and Goping, I.S. and Gorbatyuk, M.S. and Gorbunov, N.V. and Görgülü, K. and Gorojod, R.M. and Gorski, S.M. and Goruppi, S. and Gotor, C. and Gottlieb, R.A. and Gozes, I. and Gozuacik, D. and Graef, M. and Gräler, M.H. and Granatiero, V. and Grasso, D. and Gray, J.P. and Green, D.R. and Greenhough, A. and Gregory, S.L. and Griffin, E.F. and Grinstaff, M.W. and Gros, F. and Grose, C. and Gross, A.S. and Gruber, F. and Grumati, P. and Grune, T. and Gu, X. and Guan, J.L. and Guardia, C.M. and Guda, K. and Guerra, F. and Guerri, C. and Guha, P. and Guillén, C. and Gujar, S. and Gukovskaya, A. and Gukovsky, I. and Gunst, J. and Günther, A. and Guntur, A.R. and Guo, C. and Guo, C. and Guo, H. and Guo, L.W. and Guo, M. and Gupta, P. and Gupta, S.K. and Gupta, S. and Gupta, V.B. and Gupta, V. and Gustafsson, A.B. and Gutterman, D.D. and H B, R. and Haapasalo, A. and Haber, J.E. and Hać, A. and Hadano, S. and Hafrén, A.J. and Haidar, M. and Hall, B.S. and Halldén, G. and Hamacher-Brady, A. and Hamann, A. and Hamasaki, M. and Han, W. and Hansen, M. and Hanson, P.I. and Hao, Z. and Harada, M. and Harhaji-Trajkovic, L. and Hariharan, N. and Haroon, N. and Harris, J. and Hasegawa, T. and Hasima Nagoor, N. and Haspel, J.A. and Haucke, V. and Hawkins, W.D. and Hay, B.A. and Haynes, C.M. and Hayrabedyan, S.B. and Hays, T.S. and He, C. and He, Q. and He, R.R. and He, Y.W. and He, Y.Y. and Heakal, Y. and Heberle, A.M. and Hejtmancik, J.F. and Helgason, G.V. and Henkel, V. and Herb, M. and Hergovich, A. and Herman-Antosiewicz, A. and Hernández, A. and Hernandez, C. and Hernandez-Diaz, S. and Hernandez-Gea, V. and Herpin, A. and Herreros, J. and Hervás, J.H. and Hesselson, D. and Hetz, C. and Heussler, V.T. and Higuchi, Y. and Hilfiker, S. and Hill, J.A. and Hlavacek, W.S. and Ho, E.A. and Ho, I.H.T. and Ho, P.W.L. and Ho, S.L. and Ho, W.Y. and Hobbs, G.A. and Hochstrasser, M. and Hoet, P.H.M. and Hofius, D. and Hofman, P. and Höhn, A. and Holmberg, C.I. and Hombrebueno, J.R. and Yi-Ren Hong, C.W.H. and Hooper, L.V. and Hoppe, T. and Horos, R. and Hoshida, Y. and Hsin, I.L. and Hsu, H.Y. and Hu, B. and Hu, D. and Hu, L.F. and Hu, M.C. and Hu, R. and Hu, W. and Hu, Y.C. and Hu, Z.W. and Hua, F. and Hua, J. and Hua, Y. and Huan, C. and Huang, C. and Huang, C. and Huang, C. and Huang, C. and Huang, H. and Huang, K. and Huang, M.L.H. and Huang, R. and Huang, S. and Huang, T. and Huang, X. and Huang, Y.J. and Huber, T.B. and Hubert, V. and Hubner, C.A. and Hughes, S.M. and Hughes, W.E. and Humbert, M. and Hummer, G. and Hurley, J.H. and Hussain, S. and Hussain, S. and Hussey, P.J. and Hutabarat, M. and Hwang, H.Y. and Hwang, S. and Ieni, A. and Ikeda, F. and Imagawa, Y. and Imai, Y. and Imbriano, C. and Imoto, M. and Inman, D.M. and Inoki, K. and Iovanna, J. and Iozzo, R.V. and Ippolito, G. and Irazoqui, J.E. and Iribarren, P. and Ishaq, M. and Ishikawa, M. and Ishimwe, N. and Isidoro, C. and Ismail, N. and Issazadeh-Navikas, S. and Itakura, E. and Ito, D. and Ivankovic, D. and Ivanova, S. and Iyer, A.K.V. and Izquierdo, J.M. and Izumi, M. and Jäättelä, M. and Jabir, M.S. and Jackson, W.T. and Jacobo-Herrera, N. and Jacomin, A.C. and Jacquin, E. and Jadiya, P. and Jaeschke, H. and Jagannath, C. and Jakobi, A.J. and Jakobsson, J. and Janji, B. and Jansen-Dürr, P. and Jansson, P.J. and Jantsch, J. and Januszewski, S. and Jassey, A. and Jean, S. and Jeltsch-David, H. and Jendelova, P. and Jenny, A. and Jensen, T.E. and Jessen, N. and Jewell, J.L. and Ji, J. and Jia, L. and Jia, R. and Jiang, L. and Jiang, Q. and Jiang, R. and Jiang, T. and Jiang, X. and Jiang, Y. and Jimenez-Sanchez, M. and Jin, E.J. and Jin, F. and Jin, H. and Jin, L. and Jin, L. and Jin, M. and Jin, S. and Jo, E.K. and Joffre, C. and Johansen, T. and Johnson, G.V.W. and Johnston, S.A. and Jokitalo, E. and Jolly, M.K. and Joosten, L.A.B. and Jordan, J. and Joseph, B. and Ju, D. and Ju, J.S. and Ju, J. and Juárez, E. and Judith, D. and Juhász, G. and Jun, Y. and Jung, C.H. and Jung, S.C. and Jung, Y.K. and Jungbluth, H. and Jungverdorben, J. and Just, S. and Kaarniranta, K. and Kaasik, A. and Kabuta, T. and Kaganovich, D. and Kahana, A. and Kain, R. and Kajimura, S. and Kalamvoki, M. and Kalia, M. and Kalinowski, D.S. and Kaludercic, N. and Kalvari, I. and Kaminska, J. and Kaminskyy, V.O. and Kanamori, H. and Kanasaki, K. and Kang, C. and Kang, R. and Kang, S.S. and Kaniyappan, S. and Kanki, T. and Kanneganti, T.D. and Kanthasamy, A.G. and Kanthasamy, A. and Kantorow, M. and Kapuy, O. and Karamouzis, M.V. and Karim, M.D.R. and Karmakar, P. and Katare, R.G. and Kato, M. and Kaufmann, S.H.E. and Kauppinen, A. and Kaushal, G.P. and Kaushik, S. and Kawasaki, K. and Kazan, K. and Ke, P.Y. and Keating, D.J. and Keber, U. and Kehrl, J.H. and Keller, K.E. and Keller, C.W. and Kemper, J.K. and Kenific, C.M. and Kepp, O. and Kermorgant, S. and Kern, A. and Ketteler, R. and Keulers, T.G. and Khalfin, B. and Khalil, H. and Khambu, B. and Khan, S.Y. and Khandelwal, V.K.M. and Khandia, R. and Kho, W. and Khobrekar, N.V. and Khuansuwan, S. and Khundadze, M. and Killackey, S.A. and Kim, D. and Kim, D.R. and Kim, D.H. and Kim, D.E. and Kim, E.Y. and Kim, E.K. and Kim, H.R. and Kim, H.S. and Kim, H.R. and Kim, J.H. and Kim, J.K. and Kim, J.H. and Kim, J. and Kim, J.H. and Kim, K.I.I. and Kim, P.K. and Kim, S.J. and Kimball, S.R. and Kimchi, A. and Kimmelman, A.C. and Kimura, T. and King, M.A. and Kinghorn, K.J. and Kinsey, C.G. and Kirkin, V. and Kirshenbaum, L.A. and Kiselev, S.L. and Kishi, S. and Kitamoto, K. and Kitaoka, Y. and Kitazato, K. and Kitsis, R.N. and Kittler, J.T. and Kjaerulff, O. and Klein, P.S. and Klopstock, T. and Klucken, J. and Knævelsrud, H. and Knorr, R.L. and Ko, B.C.B. and Ko, F. and Ko, J.L. and Kobayashi, H. and Kobayashi, S. and Koch, I. and Koch, J.C. and Koenig, U. and Kögel, D. and Koh, Y.H. and Koike, M. and Kohlwein, S.D. and Kocaturk, N.M. and Komatsu, M. and König, J. and Kono, T. and Kopp, B.T. and Korcsmaros, T. and Korkmaz, G. and Korolchuk, V.I. and Korsnes, M.S. and Koskela, A. and Kota, J. and Kotake, Y. and Kotler, M.L. and Kou, Y. and Koukourakis, M.I. and Koustas, E. and Kovacs, A.L. and Kovács, T. and Koya, D. and Kozako, T. and Kraft, C. and Krainc, D. and Krämer, H. and Krasnodembskaya, A.D. and Kretz-Remy, C. and Kroemer, G. and Ktistakis, N.T. and Kuchitsu, K. and Kuenen, S. and Kuerschner, L. and Kukar, T. and Kumar, A. and Kumar, A. and Kumar, D. and Kumar, D. and Kumar, S. and Kume, S. and Kumsta, C. and Kundu, C.N. and Kundu, M. and Kunnumakkara, A.B. and Kurgan, L. and Kutateladze, T.G. and Kutlu, O. and Kwak, S.A. and Kwon, H.J. and Kwon, T.K. and Kwon, Y.T. and Kyrmizi, I. and La Spada, A. and Labonté, P. and Ladoire, S. and Laface, I. and Lafont, F. and Lagace, D.C. and Lahiri, V. and Lai, Z. and Laird, A.S. and Lakkaraju, A. and Lamark, T. and Lan, S.H. and Landajuela, A. and Lane, D.J.R. and Lane, J.D. and Lang, C.H. and Lange, C. and Langel, Ü. and Langer, R. and Lapaquette, P. and Laporte, J. and LaRusso, N.F. and Lastres-Becker, I. and Lau, W.C.Y. and Laurie, G.W. and Lavandero, S. and Law, B.Y.K. and Law, H.K.W. and Layfield, R. and Le, W. and Le Stunff, H. and Leary, A.Y. and Lebrun, J.J. and Leck, L.Y.W. and Leduc-Gaudet, J.P. and Lee, C. and Lee, C.P. and Lee, D.H. and Lee, E.B. and Lee, E.F. and Lee, G.M. and Lee, H.J. and Lee, H.K. and Lee, J.M. and Lee, J.S. and Lee, J.A. and Lee, J.Y. and Lee, J.H. and Lee, M. and Lee, M.G. and Lee, M.J. and Lee, M.S. and Lee, S.Y. and Lee, S.J. and Lee, S.Y. and Lee, S.B. and Lee, W.H. and Lee, Y.R. and Lee, Y.H. and Lee, Y. and Lefebvre, C. and Legouis, R. and Lei, Y.L. and Lei, Y. and Leikin, S. and Leitinger, G. and Lemus, L. and Leng, S. and Lenoir, O. and Lenz, G. and Lenz, H.J. and Lenzi, P. and León, Y. and Leopoldino, A.M. and Leschczyk, C. and Leskelä, S. and Letellier, E. and Leung, C.T. and Leung, P.S. and Leventhal, J.S. and Levine, B. and Lewis, P.A. and Ley, K. and Li, B. and Li, D.Q. and Li, J. and Li, J. and Li, J. and Li, K. and Li, L. and Li, M. and Li, M. and Li, M. and Li, M. and Li, M. and Li, P.L. and Li, M.Q. and Li, Q. and Li, S. and Li, T. and Li, W. and Li, W. and Li, X. and Li, Y.P. and Li, Y. and Li, Z. and Li, Z. and Li, Z. and Lian, J. and Liang, C. and Liang, Q. and Liang, W. and Liang, Y. and Liang, Y.T. and Liao, G. and Liao, L. and Liao, M. and Liao, Y.F. and Librizzi, M. and Lie, P.P.Y. and Lilly, M.A. and Lim, H.J. and Lima, T.R.R. and Limana, F. and Lin, C. and Lin, C.W. and Lin, D.S. and Lin, F.C. and Lin, J.D. and Lin, K.M. and Lin, K.H. and Lin, L.T. and Lin, P.H. and Lin, Q. and Lin, S. and Lin, S.J. and Lin, W. and Lin, X. and Lin, Y.X. and Lin, Y.S. and Linden, R. and Lindner, P. and Ling, S.C. and Lingor, P. and Linnemann, A.K. and Liou, Y.C. and Lipinski, M.M. and Lipovšek, S. and Lira, V.A. and Lisiak, N. and Liton, P.B. and Liu, C. and Liu, C.H. and Liu, C.F. and Liu, C.H. and Liu, F. and Liu, H. and Liu, H.S. and Liu, H.F. and Liu, H. and Liu, J. and Liu, J. and Liu, J. and Liu, L. and Liu, L. and Liu, M. and Liu, Q. and Liu, W. and Liu, W. and Liu, X.H. and Liu, X. and Liu, X. and Liu, X. and Liu, X. and Liu, Y. and Liu, Y. and Liu, Y. and Liu, Y. and Liu, Y. and Livingston, J.A. and Lizard, G. and Lizcano, J.M. and Ljubojevic-Holzer, S. and LLeonart, M.E. and Llobet-Navàs, D. and Llorente, A. and Lo, C.H. and Lobato-Márquez, D. and Long, Q. and Long, Y.C. and Loos, B. and Loos, J.A. and López, M.G. and López-Doménech, G. and López-Guerrero, J.A. and López-Jiménez, A.T. and López-Pérez, O. and López-Valero, I. and Lorenowicz, M.J. and Lorente, M. and Lorincz, P. and Lossi, L. and Lotersztajn, S. and Lovat, P.E. and Lovell, J.F. and Lovy, A. and Lőw, P. and Lu, G. and Lu, H. and Lu, J.H. and Lu, J.J. and Lu, M. and Lu, S. and Luciani, A. and Lucocq, J.M. and Ludovico, P. and Luftig, M.A. and Luhr, M. and Luis-Ravelo, D. and Lum, J.J. and Luna-Dulcey, L. and Lund, A.H. and Lund, V.K. and Lünemann, J.D. and Lüningschrör, P. and Luo, H. and Luo, R. and Luo, S. and Luo, Z. and Luparello, C. and Lüscher, B. and Luu, L. and Lyakhovich, A. and Lyamzaev, K.G. and Lystad, A.H. and Lytvynchuk, L. and Ma, A.C. and Ma, C. and Ma, M. and Ma, N.F. and Ma, Q.H. and Ma, X. and Ma, Y. and Ma, Z. and MacDougald, O.A. and Macian, F. and MacIntosh, G.C. and MacKeigan, J.P. and Macleod, K.F. and Maday, S. and Madeo, F. and Madesh, M. and Madl, T. and Madrigal-Matute, J. and Maeda, A. and Maejima, Y. and Magarinos, M. and Mahavadi, P. and Maiani, E. and Maiese, K. and Maiti, P. and Maiuri, M.C. and Majello, B. and Major, M.B. and Makareeva, E. and Malik, F. and Mallilankaraman, K. and Malorni, W. and Maloyan, A. and Mammadova, N. and Man, G.C.W. and Manai, F. and Mancias, J.D. and Mandelkow, E.M. and Mandell, M.A. and Manfredi, A.A. and Manjili, M.H. and Manjithaya, R. and Manque, P. and Manshian, B.B. and Manzano, R. and Manzoni, C. and Mao, K. and Marchese, C. and Marchetti, S. and Marconi, A.M. and Marcucci, F. and Mardente, S. and Mareninova, O.A. and Margeta, M. and Mari, M. and Marinelli, S. and Marinelli, O. and Mariño, G. and Mariotto, S. and Marshall, R.S. and Marten, M.R. and Martens, S. and Martin, A.P.J. and Martin, K.R. and Martin, S. and Martin, S. and Martín-Segura, A. and Martín-Acebes, M.A. and Martin-Burriel, I. and Martin-Rincon, M. and Martin-Sanz, P. and Martina, J.A. and Martinet, W. and Martinez, A. and Martinez, A. and Martinez, J. and Martinez Velazquez, M. and Martinez-Lopez, N. and Martinez-Vicente, M. and Martins, D.O. and Martins, J.O. and Martins, W.K. and Martins-Marques, T. and Marzetti, E. and Masaldan, S. and Masclaux-Daubresse, C. and Mashek, D.G. and Massa, V. and Massieu, L. and Masson, G.R. and Masuelli, L. and Masyuk, A.I. and Masyuk, T.V. and Matarrese, P. and Matheu, A. and Matoba, S. and Matsuzaki, S. and Mattar, P. and Matte, A. and Mattoscio, D. and Mauriz, J.L. and Mauthe, M. and Mauvezin, C. and Maverakis, E. and Maycotte, P. and Mayer, J. and Mazzoccoli, G. and Mazzoni, C. and Mazzulli, J.R. and McCarty, N. and McDonald, C. and McGill, M.R. and McKenna, S.L. and McLaughlin, B.A. and McLoughlin, F. and McNiven, M.A. and McWilliams, T.G. and Mechta-Grigoriou, F. and Medeiros, T.C. and Medina, D.L. and Megeney, L.Y. and Megyeri, K. and Mehrpour, M. and Mehta, J.L. and Meijer, A.J. and Meijer, A.H. and Mejlvang, J. and Meléndez, A. and Melk, A. and Memisoglu, G. and Mendes, A.F. and Meng, D. and Meng, F. and Meng, T. and Menna-Barreto, R. and Menon, M.B. and Mercer, C. and Mercier, A.E. and Mergny, J.L. and Merighi, A. and Merkley, S.D. and Merla, G. and Meske, V. and Mestre, A.C. and Metur, S.P. and Meyer, C. and Meyer, H. and Mi, W. and Mialet-Perez, J. and Miao, J. and Micale, L. and Miki, Y. and Milan, E. and Milczarek, M. and Miller, D.L. and Miller, S.I. and Miller, S. and Millward, S.W. and Milosevic, I. and Minina, E.A. and Mirzaei, H. and Mirzaei, H.R. and Mirzaei, M. and Mishra, A. and Mishra, N. and Mishra, P.K. and Misirkic Marjanovic, M. and Misasi, R. and Misra, A. and Misso, G. and Mitchell, C. and Mitou, G. and Miura, T. and Miyamoto, S. and Miyazaki, M. and Miyazaki, M. and Miyazaki, T. and Miyazawa, K. and Mizushima, N. and Mogensen, T.H. and Mograbi, B. and Mohammadinejad, R. and Mohamud, Y. and Mohanty, A. and Mohapatra, S. and Möhlmann, T. and Mohmmed, A. and Moles, A. and Moley, K.H. and Molinari, M. and Mollace, V. and Møller, A.B. and Mollereau, B. and Mollinedo, F. and Montagna, C. and Monteiro, M.J. and Montella, A. and Montes, L.R. and Montico, B. and Mony, V.K. and Monzio Compagnoni, G. and Moore, M.N. and Moosavi, M.A. and Mora, A.L. and Mora, M. and Morales-Alamo, D. and Moratalla, R. and Moreira, P.I. and Morelli, E. and Moreno, S. and Moreno-Blas, D. and Moresi, V. and Morga, B. and Morgan, A.H. and Morin, F. and Morishita, H. and Moritz, O.L. and Moriyama, M. and Moriyasu, Y. and Morleo, M. and Morselli, E. and Moruno-Manchon, J.F. and Moscat, J. and Mostowy, S. and Motori, E. and Moura, A.F. and Moustaid-Moussa, N. and Mrakovcic, M. and Muciño-Hernández, G. and Mukherjee, A. and Mukhopadhyay, S. and Mulcahy Levy, J.M. and Mulero, V. and Muller, S. and Münch, C. and Munjal, A. and Munoz-Canoves, P. and Muñoz-Galdeano, T. and Münz, C. and Murakawa, T. and Muratori, C. and Murphy, B.M. and Murphy, J.P. and Murthy, A. and Myöhänen, T.T. and Mysorekar, I.U. and Mytych, J. and Nabavi, S.M. and Nabissi, M. and Nagy, P. and Nah, J. and Nahimana, A. and Nakagawa, I. and Nakamura, K. and Nakatogawa, H. and Nandi, S.S. and Nanjundan, M. and Nanni, M. and Napolitano, G. and Nardacci, R. and Narita, M. and Nassif, M. and Nathan, I. and Natsumeda, M. and Naude, R.J. and Naumann, C. and Naveiras, O. and Navid, F. and Nawrocki, S.T. and Nazarko, T.Y. and Nazio, F. and Negoita, F. and Neill, T. and Neisch, A.L. and Neri, L.M. and Netea, M.G. and Neubert, P. and Neufeld, T.P. and Neumann, D. and Neutzner, A. and Newton, P.T. and Ney, P.A. and Nezis, I.P. and Ng, C.C.W. and Ng, T.B. and Nguyen, H.T.T. and Nguyen, L.T. and Ni, H.M. and Ní Cheallaigh, C. and Ni, Z. and Nicolao, M.C. and Nicoli, F. and Nieto-Diaz, M. and Nilsson, P. and Ning, S. and Niranjan, R. and Nishimune, H. and Niso-Santano, M. and Nixon, R.A. and Nobili, A. and Nobrega, C. and Noda, T. and Nogueira-Recalde, U. and Nolan, T.M. and Nombela, I. and Novak, I. and Novoa, B. and Nozawa, T. and Nukina, N. and Nussbaum-Krammer, C. and Nylandsted, J. and O'Donovan, T.R. and O'Leary, S.M. and O'Rourke, E.J. and O'Sullivan, M.P. and O'Sullivan, T.E. and Oddo, S. and Oehme, I. and Ogawa, M. and Ogier-Denis, E. and Ogmundsdottir, M.H. and Ogretmen, B. and Oh, G.T. and Oh, S.H. and Oh, Y.J. and Ohama, T. and Ohashi, Y. and Ohmuraya, M. and Oikonomou, V. and Ojha, R. and Okamoto, K. and Okazawa, H. and Oku, M. and Oliván, S. and Oliveira, J.M.A. and Ollmann, M. and Olzmann, J.A. and Omari, S. and Omary, M.B. and Önal, G. and Ondrej, M. and Ong, S.B. and Ong, S.G. and Onnis, A. and Orellana, J.A. and Orellana-Muñoz, S. and Ortega-Villaizan, M.D.M. and Ortiz-Gonzalez, X.R. and Ortona, E. and Osiewacz, H.D. and Osman, A.H.K. and Osta, R. and Otegui, M.S. and Otsu, K. and Ott, C. and Ottobrini, L. and Ou, J.H.J. and Outeiro, T.F. and Oynebraten, I. and Ozturk, M. and Pagès, G. and Pahari, S. and Pajares, M. and Pajvani, U.B. and Pal, R. and Paladino, S. and Pallet, N. and Palmieri, M. and Palmisano, G. and Palumbo, C. and Pampaloni, F. and Pan, L. and Pan, Q. and Pan, W: and Pan, X. and Panasyuk, G. and Pandey, R. and Pandey, U.B. and Pandya, V. and Paneni, F. and Pang, S.Y. and Panzarini, E. and Papademetrio, D.L. and Papaleo, E. and Papinski, D. and Papp, D. and Park, E.C. and Park, H.T. and Park, J.M. and Park, J.I. and Park, J.T. and Park, J. and Park, S.C. and Park, S.Y. and Parola, A.H. and Parys, J.B. and Pasquier, A. and Pasquier, B. and Passos, J.F. and Pastore, N. and Patel, H.H. and Patschan, D. and Pattingre, S. and Pedraza-Alva, G. and Pedraza-Chaverri, J. and Pedrozo, Z. and Pei, G. and Pei, J. and Peled-Zehavi, H. and Pellegrini, J.M. and Pelletier, J. and Peñalva, M.A. and Peng, D. and Peng, Y. and Penna, F. and Pennuto, M. and Pentimalli, F. and Pereira, C.M.F. and Pereira, G.J.S. and Pereira, L.C. and Pereira de Almeida, L. and Perera, N.D. and Pérez-Lara, A. and Perez-Oliva, A.B. and Pérez-Pérez, M.E. and Periyasamy, P. and Perl, A. and Perrotta, C. and Perrotta, I. and Pestell, R.G. and Petersen, M. and Petrache, I. and Petrovski, G. and Pfirrmann, T. and Pfister, A.S. and Philips, J.A. and Pi, H. and Picca, A. and Pickrell, A.M. and Picot, S. and Pierantoni, G.M. and Pierdominici, M. and Pierre, P. and Pierrefite-Carle, V. and Pierzynowska, K. and Pietrocola, F. and Pietruczuk, M. and Pignata, C. and Pimentel-Muiños, F.X. and Pinar, M. and Pinheiro, R.O. and Pinkas-Kramarski, R. and Pinton, P. and Pircs, K. and Piya, S. and Pizzo, P. and Plantinga, T.S. and Platta, H.W. and Plaza-Zabala, A. and Plomann, M. and Plotnikov, E.Y. and Plun-Favreau, H. and Pluta, R. and Pocock, R. and Pöggeler, S. and Pohl, C. and Poirot, M. and Poletti, A. and Ponpuak, M. and Popelka, H. and Popova, B. and Porta, H. and Porte Alcon, S. and Portilla-Fernandez, E. and Post, M. and Potts, M.B. and Poulton, J. and Powers, T. and Prahlad, V. and Prajsnar, T.K. and Praticò, D. and Prencipe, R. and Priault, M. and Proikas-Cezanne, T. and Promponas, V.J. and Proud, C.G. and Puertollano, R. and Puglielli, L. and Pulinilkunnil, T. and Puri, D. and Puri, R. and Puyal, J. and Qi, X. and Qi, Y. and Qian, W. and Qiang, L. and Qiu, Y. and Quadrilatero, J. and Quarleri, J. and Raben, N. and Rabinowich, H. and Ragona, D. and Ragusa, M.J. and Rahimi, N. and Rahmati, M. and Raia, V. and Raimundo, N. and Rajasekaran, N.S. and Ramachandra Rao, S. and Rami, A. and Ramírez-Pardo, I. and Ramsden, D.B. and Randow, F. and Rangarajan, P.N. and Ranieri, D. and Rao, H. and Rao, L. and Rao, R. and Rathore, S. and Ratnayaka, J.A. and Ratovitski, E.A. and Ravanan, P. and Ravegnini, G. and Ray, S.K. and Razani, B. and Rebecca, V. and Reggiori, F. and Régnier-Vigouroux, A. and Reichert, A.S. and Reigada, D. and Reiling, J.H. and Rein, T. and Reipert, S. and Rekha, R.S. and Ren, H. and Ren, J. and Ren, W. and Renault, T. and Renga, G. and Reue, K. and Rewitz, K. and Ribeiro de Andrade Ramos, B. and Riazuddin, S.A. and Ribeiro-Rodrigues, T.M. and Ricci, J.E. and Ricci, R. and Riccio, V. and Richardson, D.R. and Rikihisa, Y. and Risbud, M.V. and Risueño, R.M. and Ritis, K. and Rizza, S. and Rizzuto, R. and Roberts, H.C. and Roberts, L.D. and Robinson, K.J. and Roccheri, M.C. and Rocchi, S. and Rodney, G.G. and Rodrigues, T. and Rodrigues Silva, V.R. and Rodriguez, A. and Rodriguez-Barrueco, R. and Rodriguez-Henche, N. and Rodriguez-Rocha, H. and Roelofs, J. and Rogers, R.S. and Rogov, V.V. and Rojo, A.I. and Rolka, K. and Romanello, V. and Romani, L. and Romano, A. and Romano, P.S. and Romeo-Guitart, D. and Romero, L.C. and Romero, M. and Roney, J.C. and Rongo, C. and Roperto, S. and Rosenfeldt, M.T. and Rosenstiel, P. and Rosenwald, A.G. and Roth, K.A. and Roth, L. and Roth, S. and Rouschop, K.M.A. and Roussel, B.D. and Roux, S. and Rovere-Querini, P. and Roy, A. and Rozieres, A. and Ruano, D. and Rubinsztein, D.C. and Rubtsova, M.P. and Ruckdeschel, K. and Ruckenstuhl, C. and Rudolf, E. and Rudolf, R. and Ruggieri, A. and Ruparelia, A.A. and Rusmini, P. and Russell, R.R. and Russo, G.L. and Russo, M. and Russo, R. and Ryabaya, O.O. and Ryan, K.M. and Ryu, K.Y. and Sabater-Arcis, M. and Sachdev, U. and Sacher, M. and Sachse, C. and Sadhu, A. and Sadoshima, J. and Safren, N. and Saftig, P. and Sagona, A.P. and Sahay, G. and Sahebkar, A. and Sahin, M. and Sahin, O. and Sahni, S. and Saito, N. and Saito, S. and Saito, T. and Sakai, R. and Sakai, Y. and Sakamaki, J.I. and Saksela, K. and Salazar, G. and Salazar-Degracia, A. and Salekdeh, G.H. and Saluja, A.K. and Sampaio-Marques, B. and Sanchez, M.C. and Sanchez-Alcazar, J.A. and Sanchez-Vera, V. and Sancho-Shimizu, V. and Sanderson, J.T. and Sandri, M. and Santaguida, S. and Santambrogio, L. and Santana, M.M. and Santoni, G. and Sanz, A. and Sanz, P. and Saran, S. and Sardiello, M. and Sargeant, T.J. and Sarin, A. and Sarkar, C. and Sarkar, S. and Sarrias, M.R. and Sarkar, S. and Sarmah, D.T. and Sarparanta, J. and Sathyanarayan, A. and Sathyanarayanan, R. and Scaglione, K.M. and Scatozza, F. and Schaefer, L. and Schafer, Z.T. and Schaible, U.E. and Schapira, A.H.V. and Scharl, M. and Schatzl, H.M. and Schein, C.H. and Scheper, W. and Scheuring, D. and Schiaffino, M.V. and Schiappacassi, M. and Schindl, R. and Schlattner, U. and Schmidt, O. and Schmitt, R. and Schmidt, S.D. and Schmitz, I. and Schmukler, E. and Schneider, A. and Schneider, B.E. and Schober, R. and Schoijet, A.C. and Schott, M.B. and Schramm, M. and Schröder, B. and Schuh, K. and Schüller, C. and Schulze, R.L. and Schürmanns, L. and Schwamborn, J.C. and Schwarten, M. and Scialo, F. and Sciarretta, S. and Scott, M.J. and Scotto, K.W. and Scovassi, A.I. and Scrima, A. and Scrivo, A. and Sebastian, D. and Sebti, S. and Sedej, S. and Segatori, L. and Segev, N. and Seglen, P.O. and Seiliez, I. and Seki, E. and Selleck, S.B. and Sellke, F.W. and Selsby, J.T. and Sendtner, M. and Senturk, S. and Seranova, E. and Sergi, C. and Serra-Moreno, R. and Sesaki, H. and Settembre, C. and Setty, S.R.G. and Sgarbi, G. and Sha, O. and Shacka, J.J. and Shah, J.A. and Shang, D. and Shao, C. and Shao, F. and Sharbati, S. and Sharkey, L.M. and Sharma, D. and Sharma, G. and Sharma, K. and Sharma, P. and Sharma, S. and Shen, H.M. and Shen, H. and Shen, J. and Shen, M. and Shen, W. and Shen, Z. and Sheng, R. and Sheng, Z. and Sheng, Z.H. and Shi, J. and Shi, X. and Shi, Y.H. and Shiba-Fukushima, K. and Shieh, J.J. and Shimada, Y. and Shimizu, S. and Shimozawa, M. and Shintani, T. and Shoemaker, C.J. and Shojaei, S. and Shoji, I. and Shravage, B.V. and Shridhar, V. and Shu, C.W. and Shu, H.B. and Shui, K. and Shukla, A.K. and Shutt, T.E. and Sica, V. and Siddiqui, A. and Sierra, A. and Sierra-Torre, V. and Signorelli, S. and Sil, P. and Silva, B.J.A. and Silva, J.D. and Silva-Pavez, E. and Silvente-Poirot, S. and Simmonds, R.E. and Simon, A.K. and Simon, H.U. and Simons, M. and Singh, A. and Singh, L.P. and Singh, R. and Singh, S.V. and Singh, S.K. and Singh, S.B. and Singh, S. and Singh, S.P. and Sinha, D. and Sinha, R.A. and Sinha, S. and Sirko, A. and Sirohi, K. and Sivridis, E.L. and Skendros, P. and Skirycz, A. and Slaninová, I. and Smaili, S.S. and Smertenko, A. and Smith, M.D. and Soenen, S.J. and Sohn, E.J. and Sok, S.P.M. and Solaini, G. and Soldati, T. and Soleimanpour, S.A. and Soler, R.M. and Solovchenko, A. and Somarelli, J.A. and Sonawane, A. and Song, F. and Song, H.K. and Song, J.X. and Song, K. and Song, Z. and Soria, L.R. and Sorice, M. and Soukas, A.A. and Soukup, S.F. and Sousa, D. and Sousa, N. and Spagnuolo, P.A. and Spector, S.A. and Srinivas Bharath, M.M. and St Clair, D. and Stagni, V. and Staiano, L. and Stalnecker, C.A. and Stankov, M.V. and Stathopulos, P.B. and Stefan, K. and Stefan, S.M. and Stefanis, L. and Steffan, J.S. and Steinkasserer, A. and Stenmark, H. and Sterneckert, J. and Stevens, C. and Stoka, V. and Storch, S. and Stork, B. and Strappazzon, F. and Strohecker, A.M. and Stupack, D.G. and Su, H. and Su, L.Yy and Su, L. and Suarez-Fontes, A.M. and Subauste, C.S. and Subbian, S. and Subirada, P.V. and Sudhandiran, G. and Sue, C.M. and Sui, X. and Summers, C. and Sun, G. and Sun, J. and Sun, K. and Sun, M.X. and Sun, Q. and Sun, Y. and Sun, Z. and Sunahara, K.K.S. and Sundberg, E. and Susztak, K. and Sutovsky, P. and Suzuki, H. and Sweeney, G. and Symons, J.D. and Sze, S.C.W. and Szewczyk, N.J. and Tabęcka-Łonczynska, A. and Tabolacci, C. and Tacke, F. and Taegtmeyer, H. and Tafani, M. and Tagaya, M. and Tai, H. and Tait, S.W.G. and Takahashi, Y. and Takats, S. and Talwar, P. and Tam, C. and Tam, S.Y. and Tampellini, D. and Tamura, A. and Tan, C.T. and Tan, E.K. and Tan, Y.Q. and Tanaka, M. and Tanaka, M. and Tang, D. and Tang, J. and Tang, T.S. and Tanida, I. and Tao, Z. and Taouis, M. and Tatenhorst, L. and Tavernarakis, N. and Taylor, A. and Taylor, G.A. and Taylor, J.M. and Tchetina, E. and Tee, A.R. and Tegeder, I. and Teis, D. and Teixeira, N. and Teixeira-Clerc, F. and Tekirdag, K.A. and Tencomnao, T. and Tenreiro, S. and Tepikin, A.V. and Testillano, P.S. and Tettamanti, G. and Tharaux, P.L. and Thedieck, K. and Thekkinghat, A.A. and Thellung, S. and Thinwa, J.W. and Thirumalaikumar, V.P. and Thomas, S.M. and Thomes, P.G. and Thorburn, A. and Thukral, L. and Thum, T. and Thumm, M. and Tian, L. and Tichy, A. and Till, A. and Timmerman, V. and Titorenko, V.I. and Todi, S.V. and Todorova, K. and Toivonen, J.M. and Tomaipitinca, L. and Tomar, D. and Tomas-Zapico, C. and Tomić, S. and Tong, B.C.K. and Tong, C. and Tong, X. and Tooze, S.A. and Torgersen, M.L. and Torii, S. and Torres-López, L. and Torriglia, A. and Towers, C.G. and Towns, R. and Toyokuni, S. and Trajkovic, V. and Tramontano, D. and Tran, Q.G. and Travassos, L.H. and Trelford, C.B. and Tremel, S. and Trougakos, I.P. and Tsao, B.P. and Tschan, M.P. and Tse, H.F. and Tse, T.F. and Tsugawa, H. and Tsvetkov, A.S. and Tumbarello, D.A. and Tumtas, Y. and Tuñón, M.J. and Turcotte, S. and Turk, B. and Turk, V. and Turner, B.J. and Tuxworth, R.I. and Tyler, J.K. and Tyutereva, E.V. and Uchiyama, Y. and Ugun-Klusek, A. and Uhlig, H.H. and Ułamek-Kozioł, M. and Ulasov, I.V. and Umekawa, M. and Ungermann, C. and Unno, R. and Urbe, S. and Uribe-Carretero, E. and Üstün, S. and Uversky, V.N. and Vaccari, T. and Vaccaro, M.I. and Vahsen, B.F. and Vakifahmetoglu-Norberg, H. and Valdor, R. and Valente, M.J. and Valko, A. and Vallee, R.B. and Valverde, A.M. and Van den Berghe, G. and van der Veen, S. and Van Kaer, L. and van Loosdregt, J. and van Wijk, S.J.L. and Vandenberghe, W. and Vanhorebeek, I. and Vannier-Santos, M.A. and Vannini, N. and Vanrell, M.C. and Vantaggiato, C. and Varano, G. and Varela-Nieto, I. and Varga, M. and Vasconcelos, M.H. and Vats, S. and Vavvas, D.G. and Vega-Naredo, I. and Vega-Rubin-de-Celis, S. and Velasco, G. and Velázquez, A.P. and Vellai, T. and Vellenga, E. and Velotti, F. and Verdier, M. and Verginis, P. and Vergne, I. and Verkade, P. and Verma, M. and Verstreken, P. and Vervliet, T. and Vervoorts, J. and Vessoni, A.T. and Victor, V.M. and Vidal, M. and Vidoni, C. and Vieira, O.V. and Vierstra, R.D. and Viganó, S. and Vihinen, H. and Vijayan, V. and Vila, M. and Vilar, M. and Villalba, J.M. and Villalobo, A. and Villarejo-Zori, B. and Villarroya, F. and Villarroya, J. and Vincent, O. and Vindis, C. and Viret, C. and Viscomi, M.T. and Visnjic, D. and Vitale, I. and Vocadlo, D.J. and Voitsekhovskaja, O.V. and Volonté, C. and Volta, M. and Vomero, M. and Von Haefen, C. and Vooijs, M.A. and Voos, W. and Vucicevic, L. and Wade-Martins, R. and Waguri, S. and Waite, K.A. and Wakatsuki, S. and Walker, D.W. and Walker, M.J. and Walker, S.A. and Walter, J. and Wandosell, F.G. and Wang, B. and Wang, C.Y. and Wang, C. and Wang, C. and Wang, C. and Wang, C.Y. and Wang, D. and Wang, F. and Wang, F. and Wang, F. and Wang, G. and Wang, H. and Wang, H. and Wang, H. and Wang, H.G. and Wang, J. and Wang, J. and Wang, J. and Wang, J. and Wang, K. and Wang, L. and Wang, L. and Wang, M.H. and Wang, M. and Wang, N. and Wang, P. and Wang, P. and Wang, P. and Wang, P. and Wang, Q.J. and Wang, Q. and Wang, Q.K. and Wang, Q.A. and Wang, W.T. and Wang, W. and Wang, X. and Wang, X. and Wang, Y. and Wang, Y. and Wang, Y. and Wang, Y.Y. and Wang, Y. and Wang, Y. and Wang, Y. and Wang, Y. and Wang, Z. and Wang, Z. and Wang, Z. and Warnes, G. and Warnsmann, V. and Watada, H. and Watanabe, E. and Watchon, M. and Wawrzyńska, A. and Weaver, T.E. and Wegrzyn, G. and Wehman, A.M. and Wei, H. and Wei, L. and Wei, T. and Wei, Y. and Weiergräber, O.H. and Weihl, C.C. and Weindl, G. and Weiskirchen, R. and Wells, A. and Wen, R.H. and Wen, X. and Werner, A. and Weykopf, B. and Wheatley, S.P. and Whitton, J.L. and Whitworth, A.J. and Wiktorska, K. and Wildenberg, M.E. and Wileman, T. and Wilkinson, S. and Willbold, D. and Williams, B. and Williams, R.S.B. and Williams, R.L. and Williamson, P.R. and Wilson, R.A. and Winner, B. and Winsor, N.J. and Witkin, S.S. and Wodrich, H. and Woehlbier, U. and Wollert, T. and Wong, E. and Wong, J.H. and Wong, R.W. and Wong, V.K.W. and Wong, W.L. and Wu, A.G. and Wu, C. and Wu, J. and Wu, J. and Wu, K.K. and Wu, M. and Wu, S.Y. and Wu, S. and Wu, S.Y. and Wu, S. and Wu, W.K.K. and Wu, X. and Wu, X. and Wu, Y.W. and Wu, Y. and Xavier, R.J. and Xia, H. and Xia, L. and Xia, Z. and Xiang, G. and Xiang, J. and Xiang, M. and Xiang, W. and Xiao, B. and Xiao, G. and Xiao, H. and Xiao, H.T. and Xiao, J. and Xiao, L. and Xiao, S. and Xiao, Y. and Xie, B. and Xie, C.M. and Xie, M. and Xie, Y. and Xie, Z. and Xie, Z. and Xilouri, M. and Xu, C. and Xu, E. and Xu, H. and Xu, J. and Xu, J.R. and Xu, L. and Xu, W.W. and Xu, X. and Xue, Y. and Yakhine-Diop, S.M.S. and Yamaguchi, M. and Yamaguchi, O. and Yamamoto, A. and Yamashina, S. and Yan, S. and Yan, S.J. and Yan, Z. and Yanagi, Y. and Yang, C. and Yang, D.S. and Yang, H. and Yang, H.T. and Yang, H. and Yang, J.M. and Yang, J. and Yang, J. and Yang, L. and Yang, L. and Yang, M. and Yang, P.M. and Yang, Q. and Yang, S. and Yang, S. and Yang, S.F. and Yang, W. and Yang, W.Y. and Yang, X. and Yang, X. and Yang, Y. and Yang, Y. and Yao, H. and Yao, S. and Yao, X. and Yao, Y.G. and Yao, Y.M. and Yasui, T. and Yazdankhah, M. and Yen, P.M. and Yi, C. and Yin, X.M. and Yin, Y. and Yin, Z. and Yin, Z. and Ying, M. and Ying, Z. and Yip, C.K. and Yiu, S.P.T. and Yoo, Y.H. and Yoshida, K. and Yoshii, S.R. and Yoshimori, T. and Yousefi, B. and Yu, B.