Abdelilah-Seyfried, Salim

Unilateral dampening of Bmp activity by Nodal generates cardiac left-right asymmetry.
Veerkamp, J., Rudolph, F., Cseresnyes, Z. ORCID: https://orcid.org/0000-0002-6574-2588, Priller, F., Otten, C. ORCID: https://orcid.org/0000-0002-8230-7350, Renz, M., Schaefer, L. and Abdelilah-Seyfried, S. ORCID: https://orcid.org/0000-0003-3183-3841
Developmental Cell 24 (6): 660-667. 25 March 2013

Bmp signaling exerts opposite effects on cardiac differentiation.
de Pater, E., Ciampricotti, M., Priller, F., Veerkamp, J., Strate, I., Smith, K., Lagendijk, A.K., Schilling, T.F., Herzog, W., Abdelilah-Seyfried, S. ORCID: https://orcid.org/0000-0003-3183-3841, Hammerschmidt, M. and Bakkers, J.
Circulation Research 110 (4): 578-587. 17 February 2012

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Lange, M., Kaynak, B., Foerster, U.B., Toenjes, M., Fischer, J.J., Grimm, C., Schlesinger, J. ORCID: https://orcid.org/0009-0005-5310-9717, Just, S., Dunkel, I., Krueger, T., Mebus, S., Lehrach, H., Lurz, R., Gobom, J., Rottbauer, W., Abdelilah-Seyfried, S. ORCID: https://orcid.org/0000-0003-3183-3841 and Sperling, S. ORCID: https://orcid.org/0000-0002-7135-3298
Genes & Development 22 (17): 2370-2384. 1 September 2008

Akalin, Altuna (BIMSB)

Oncogene inactivation-induced senescence facilitates tumor relapse.
Schmitt, Philipp ORCID: https://orcid.org/0009-0008-1643-0079, Hönig, Katrin, Norcia, Maria Teresa ORCID: https://orcid.org/0009-0007-8042-4530, Nogueira, Marta F. ORCID: https://orcid.org/0000-0002-7607-4570, Flore, Viktoria ORCID: https://orcid.org/0009-0001-3023-433X, Simó Vesperinas, Inés ORCID: https://orcid.org/0000-0001-8965-127X, Villoro-Agud, Maria ORCID: https://orcid.org/0009-0005-5525-0589, Peng, Lushan, Safyürek, Zuhal ORCID: https://orcid.org/0009-0004-8412-5069, Tariq, Mehreen ORCID: https://orcid.org/0009-0003-5217-2226, Milojkovic, Ana ORCID: https://orcid.org/0009-0001-7621-2283, Anders, Kathleen ORCID: https://orcid.org/0000-0002-0429-200X, Schröck, Evelin ORCID: https://orcid.org/0000-0002-3377-1704, Sauer, Sascha ORCID: https://orcid.org/0000-0002-4794-3693, Uyar, Bora ORCID: https://orcid.org/0000-0002-3170-4890, Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117, Willimsky, Gerald ORCID: https://orcid.org/0000-0002-9693-948X, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Martínez-Reyes, Inmaculada ORCID: https://orcid.org/0000-0003-0479-1535 and Blankenstein, Thomas ORCID: https://orcid.org/0000-0002-3357-4321
Nature Communications 17 : 6244. 15 July 2026

Multiomic and longitudinal dissection of immune dynamics associated with Parkinsonism after ciltacabtagene autoleucel therapy.
Kadel, Sofie-Katrin, Scheller, Lukas, Leipold, Alexander M., Krammer, Tobias, Raskó, Tamás, Alb, Miriam, Weis, Philipp, Leberzammer, Maria, Schmitt, Friederike, Stetter, Clara, Tamamushi, Yoko, Köck, Alicia, Köberle, Philipp, Reich, Martin, Musacchio, Thomas, Doppler, Kathrin, Sommer, Claudia, Cebulla, Nadine, McFleder, Rhonda, Ip, Chi Wang, Volkmann, Jens, Kallius, Matthias, Serfling, Sebastian E., Hartrampf, Philipp E., Buck, Andreas K., Pande, Amit ORCID: https://orcid.org/0009-0008-0826-973X, Löffler, Dennis, Gernert, Michael, Duell, Johannes, Topp, Max S., Mersi, Julia, Waldschmidt, Johannes, Einsele, Hermann, Hudecek, Michael, Saliba, Antoine-Emmanuel, Rasche, Leo and Kortüm, K. Martin
Blood Cancer Discovery 7 (4): 544-557. 1 July 2026

Multiplexed biomarkers dynamically detect heterogeneous residual neuroblastoma cell clone activity in the bone marrow niche.
Schroeer, Anna M., Winkler, Annika, Fillies, Marion, Kranig, Charleen, Karaman, Eliz, von Stetten, Felix, Zengerle, Roland, Lehnert, Michael, Blume, Alexander ORCID: https://orcid.org/0000-0003-3045-8234, Hollander, Jan F., Lodrini, Marco, Eggert, Angelika, Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117, Astrahantseff, Kathy, Eckert, Cornelia, Deubzer, Hedwig E. ORCID: https://orcid.org/0000-0002-6115-4893 and Szymansky, Annabell ORCID: https://orcid.org/0000-0003-4797-4526
Cancer Letters 645 : 218352. 1 May 2026

Flexynesis: a deep learning toolkit for bulk multi-omics data integration for precision oncology and beyond.
Uyar, Bora ORCID: https://orcid.org/0000-0002-3170-4890, Savchyn, Taras, Naghsh Nilchi, Amirhossein ORCID: https://orcid.org/0000-0003-1329-3044, Sarigun, Ahmet ORCID: https://orcid.org/0009-0003-2715-5344, Wurmus, Ricardo ORCID: https://orcid.org/0009-0003-0140-4189, Shaik, Mohammed Maqsood, Grüning, Björn ORCID: https://orcid.org/0000-0002-3079-6586, Franke, Vedran ORCID: https://orcid.org/0000-0003-3606-6792 and Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117
Nature Communications 16 : 8261. 12 September 2025

Evaluating large language model workflows in clinical decision support for triage and referral and diagnosis.
Gaber, F. ORCID: https://orcid.org/0009-0004-5512-8527, Shaik, M., Allega, F., Bilecz, A.J., Busch, F., Goon, K., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
NPJ Digital Medicine 8 (1): 263. 9 May 2025

Enhancing biomarker based oncology trial matching using large language models.
Al Khoury, N., Shaik, M., Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
NPJ Digital Medicine 8 (1): 250. 6 May 2025

Herpesviruses mimic zygotic genome activation to promote viral replication.
Neugebauer, E., Walter, S., Tan, J., Drayman, N., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, van Gent, M., Pennisi, S., Veratti, P., Stein, K.S., Welker, I., Tay, S., Verjans, G.M.G.M., Timmers, H.T.M., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Ensser, A., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806 and Full, F.
Nature Communications 16 (1): 710. 16 January 2025

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T. ORCID: https://orcid.org/0000-0002-9075-103X, Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Ishihama, Y., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Nature Communications 15 (1): 3146. 11 April 2024

The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation.
Benedum, J. ORCID: https://orcid.org/0000-0003-4475-7577, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Appel, L.M. ORCID: https://orcid.org/0000-0002-6769-0777, Walch, L., Bruno, M. ORCID: https://orcid.org/0000-0002-8401-7744, Schneeweiss, R., Gruber, J., Oberndorfer, H., Frank, E., Strobl, X., Polyansky, A. ORCID: https://orcid.org/0000-0002-1011-2706, Zagrovic, B. ORCID: https://orcid.org/0000-0003-3814-3675, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Slade, D. ORCID: https://orcid.org/0000-0002-0052-5910
Nature Communications 14 (1): 7912. 30 November 2023

Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Cauchy, P. ORCID: https://orcid.org/0000-0002-0659-0799, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Giefing, M., Fornes, O. ORCID: https://orcid.org/0000-0002-5969-3054, Vankadari, N. ORCID: https://orcid.org/0000-0001-9363-080X, Assi, S.A., Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Weniger, M.A., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Anagnostopoulos, I. ORCID: https://orcid.org/0000-0002-5043-6043, Bukur, T., Casarotto, M.G. ORCID: https://orcid.org/0000-0002-0571-7671, Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Edginton-White, B., Gebhardt, J.C.M. ORCID: https://orcid.org/0000-0003-1900-600X, Grau, M., Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Hansmann, M.L., Hartmann, S. ORCID: https://orcid.org/0000-0003-3424-1091, Huber, L., Kärgel, E., Lusatis, S., Noerenberg, D., Obier, N., Pannicke, U. ORCID: https://orcid.org/0000-0002-0929-1794, Fischer, A. ORCID: https://orcid.org/0000-0002-7145-2544, Reisser, A., Rosenwald, A., Schwarz, K. ORCID: https://orcid.org/0000-0003-3178-5990, Sundararaj, S., Weilemann, A. ORCID: https://orcid.org/0009-0001-1340-6486, Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Xu, W., Lenz, G. ORCID: https://orcid.org/0000-0002-4728-1693, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Wasserman, W.W. ORCID: https://orcid.org/0000-0001-6098-6412, Cockerill, P.N. ORCID: https://orcid.org/0000-0002-4410-8174, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Siebert, R., Küppers, R., Grosschedl, R. ORCID: https://orcid.org/0000-0002-0058-1250, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Bonifer, C. ORCID: https://orcid.org/0000-0002-4267-0825 and Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413
Nature Communications 14 (1): 6947. 7 November 2023

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M. ORCID: https://orcid.org/0000-0002-6769-0777, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Benedum, J. ORCID: https://orcid.org/0000-0003-4475-7577, Grishkovskaya, I. ORCID: https://orcid.org/0000-0003-0164-9373, Strobl, X., Polyansky, A. ORCID: https://orcid.org/0000-0002-1011-2706, Ammann, G. ORCID: https://orcid.org/0000-0003-2135-058X, Platzer, S. ORCID: https://orcid.org/0000-0002-2518-6273, Neudolt, A. ORCID: https://orcid.org/0000-0002-5298-1205, Wunder, A., Walch, L., Kaiser, S., Zagrovic, B. ORCID: https://orcid.org/0000-0003-3814-3675, Djinovic-Carugo, K. ORCID: https://orcid.org/0000-0003-0252-2972, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Slade, D. ORCID: https://orcid.org/0000-0002-0052-5910
Nature Communications 14 (1): 166. 11 January 2023

A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Cui, C., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Del Bel, K.L., Eibel, H., Feng, X., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Gebhardt, J.C.M., Götz, A., Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Xiong, E. ORCID: https://orcid.org/0000-0001-5124-6922, Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Rosenzweig, S.D., Schwarz, K., Turvey, S.E. and Wang, J.Y.
Science Immunology 8 (79): eade7953. January 2023

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D. ORCID: https://orcid.org/0000-0001-5948-0932, Hörtenhuber, M. ORCID: https://orcid.org/0000-0002-5599-5565, Balwierz, P.J. ORCID: https://orcid.org/0000-0002-1548-4605, Zehnder, T. ORCID: https://orcid.org/0000-0002-4127-2673, Mukarram, A.K., Nepal, C., Várnai, C. ORCID: https://orcid.org/0000-0003-0048-9507, Hadzhiev, Y. ORCID: https://orcid.org/0000-0002-1134-4904, Jimenez-Gonzalez, A. ORCID: https://orcid.org/0000-0001-7702-6135, Li, N. ORCID: https://orcid.org/0000-0002-8919-2357, Wragg, J., D'Orazio, F.M., Relic, D. ORCID: https://orcid.org/0000-0001-6237-3345, Pachkov, M. ORCID: https://orcid.org/0000-0001-7616-6435, Díaz, N. ORCID: https://orcid.org/0000-0002-0319-3448, Hernández-Rodríguez, B. ORCID: https://orcid.org/0000-0002-5118-8715, Chen, Z. ORCID: https://orcid.org/0000-0002-8376-7367, Stoiber, M., Dong, M. ORCID: https://orcid.org/0000-0003-4084-3099, Stevens, I. ORCID: https://orcid.org/0000-0003-3823-1499, Ross, S.E., Eagle, A., Martin, R., Obasaju, O. ORCID: https://orcid.org/0000-0001-5952-3103, Rastegar, S. ORCID: https://orcid.org/0000-0003-4411-5646, McGarvey, A.C. ORCID: https://orcid.org/0000-0003-3838-1139, Kopp, W. ORCID: https://orcid.org/0000-0003-0376-0032, Chambers, E. ORCID: https://orcid.org/0000-0003-1252-8059, Wang, D. ORCID: https://orcid.org/0000-0003-0068-1005, Kim, H.R., Acemel, R.D. ORCID: https://orcid.org/0000-0003-4120-0140, Naranjo, S. ORCID: https://orcid.org/0000-0002-4529-3332, Łapiński, M. ORCID: https://orcid.org/0000-0003-4892-976X, Chong, V. ORCID: https://orcid.org/0000-0002-2547-3694, Mathavan, S., Peers, B., Sauka-Spengler, T. ORCID: https://orcid.org/0000-0001-9289-0263, Vingron, M. ORCID: https://orcid.org/0000-0002-1765-4241, Carninci, P. ORCID: https://orcid.org/0000-0001-7202-7243, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340, Burgess, S.M. ORCID: https://orcid.org/0000-0003-1147-0596, Winata, C. ORCID: https://orcid.org/0000-0002-7718-5248, van Eeden, F. ORCID: https://orcid.org/0000-0003-3483-8269, Vaquerizas, J.M. ORCID: https://orcid.org/0000-0002-6583-6541, Gómez-Skarmeta, J.L. ORCID: https://orcid.org/0000-0001-5125-4332, Onichtchouk, D. ORCID: https://orcid.org/0000-0001-6497-1445, Brown, B.J. ORCID: https://orcid.org/0000-0002-5898-5848, Bogdanovic, O. ORCID: https://orcid.org/0000-0001-5680-0056, van Nimwegen, E. ORCID: https://orcid.org/0000-0001-6338-1312, Westerfield, M. ORCID: https://orcid.org/0000-0003-1187-7839, Wardle, F.C ORCID: https://orcid.org/0000-0001-5444-1889, Daub, C.O. ORCID: https://orcid.org/0000-0002-3295-8729, Lenhard, B. ORCID: https://orcid.org/0000-0002-1114-1509 and Müller, F. ORCID: https://orcid.org/0000-0002-0996-774X
Nature Genetics 54 (7): 1037-1050. July 2022

Identifying tumor cells at the single-cell level using machine learning.
Dohmen, J. ORCID: https://orcid.org/0000-0002-7826-3025, Baranovskii, A. ORCID: https://orcid.org/0000-0001-7217-3881, Ronen, J. ORCID: https://orcid.org/0000-0003-3980-6469, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Genome Biology 23 (1): 123. 30 May 2022

Simultaneous dimensionality reduction and integration for single-cell ATAC-seq data using deep learning.
Kopp, W. ORCID: https://orcid.org/0000-0003-0376-0032, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Nature Machine Intelligence 4 (2): 162-168. February 2022

The SEQC2 epigenomics quality control (EpiQC) study.
Foox, J., Nordlund, J., Lalancette, C., Gong, T., Lacey, M., Lent, S., Langhorst, B.W., Ponnaluri, V.K.C., Williams, L., Padmanabhan, K.R., Cavalcante, R., Lundmark, A., Butler, D., Mozsary, C., Gurvitch, J., Greally, J.M., Suzuki, M., Menor, M., Nasu, M., Alonso, A., Sheridan, C., Scherer, A., Bruinsma, S., Golda, G., Muszynska, A., Łabaj, P.P., Campbell, M.A., Wos, F., Raine, A., Liljedahl, U., Axelsson, T., Wang, C., Chen, Z., Yang, Z., Li, J., Yang, X., Wang, H., Melnick, A., Guo, S., Blume, A. ORCID: https://orcid.org/0000-0003-3045-8234, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Ibanez de Caceres, I., Rodriguez-Antolin, C., Rosas, R., Davis, J.W., Ishii, J., Megherbi, D.B., Xiao, W., Liao, W., Xu, J., Hong, H., Ning, B., Tong, W., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Wang, Y., Deng, Y. and Mason, C.E. ORCID: https://orcid.org/0000-0002-1850-1642
Genome Biology 22 (1): 332. 6 December 2021

Cell-type specialization is encoded by specific chromatin topologies.
Winick-Ng, W. ORCID: https://orcid.org/0000-0002-8716-5558, Kukalev, A. ORCID: https://orcid.org/0000-0001-5847-3773, Harabula, I. ORCID: https://orcid.org/0000-0002-9094-0519, Zea-Redondo, L. ORCID: https://orcid.org/0000-0001-9064-9126, Szabó, D. ORCID: https://orcid.org/0000-0001-8109-5088, Meijer, M. ORCID: https://orcid.org/0000-0003-3314-1224, Serebreni, L. ORCID: https://orcid.org/0000-0003-3831-9722, Zhang, Y., Bianco, S. ORCID: https://orcid.org/0000-0001-5819-060X, Chiariello, A.M. ORCID: https://orcid.org/0000-0002-6112-0167, Irastorza-Azcarate, I. ORCID: https://orcid.org/0000-0001-5245-2322, Thieme, C.J. ORCID: https://orcid.org/0000-0002-1566-0971, Sparks, T.M. ORCID: https://orcid.org/0000-0002-9455-8309, Carvalho, S. ORCID: https://orcid.org/0000-0001-6436-205X, Fiorillo, L., Musella, F., Irani, E. ORCID: https://orcid.org/0000-0002-8194-960X, Triglia, E.T. ORCID: https://orcid.org/0000-0002-6059-0116, Kolodziejczyk, A.A., Abentung, A., Apostolova, G., Paul, E.J., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Kempfer, R. ORCID: https://orcid.org/0000-0002-8588-8576, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Teichmann, S.A., Dechant, G., Ungless, M.A., Nicodemi, M. ORCID: https://orcid.org/0000-0002-8416-6416, Welch, L., Castelo-Branco, G. and Pombo, A. ORCID: https://orcid.org/0000-0002-7493-6288
Nature 599 (7886): 684-691. 25 November 2021

PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel, L.M. ORCID: https://orcid.org/0000-0002-6769-0777, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Bruno, M. ORCID: https://orcid.org/0000-0002-8401-7744, Grishkovskaya, I., Kasiliauskaite, A., Kaufmann, T. ORCID: https://orcid.org/0000-0002-9734-260X, Schoeberl, U.E., Puchinger, M.G., Kostrhon, S., Ebenwaldner, C., Sebesta, M., Beltzung, E., Mechtler, K. ORCID: https://orcid.org/0000-0002-3392-9946, Lin, G., Vlasova, A., Leeb, M. ORCID: https://orcid.org/0000-0001-5114-4782, Pavri, R., Stark, A. ORCID: https://orcid.org/0000-0003-2611-0841, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Stefl, R., Bernecky, C. ORCID: https://orcid.org/0000-0003-0893-7036, Djinovic-Carugo, K. ORCID: https://orcid.org/0000-0003-0252-2972 and Slade, D. ORCID: https://orcid.org/0000-0002-0052-5910
Nature Communications 12 (1): 6078. 19 October 2021

Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge.
Sieberts, S.K. ORCID: https://orcid.org/0000-0003-1033-0954, Schaff, J., Duda, M., Pataki, B.Á., Sun, M., Snyder, P. ORCID: https://orcid.org/0000-0002-6967-2185, Daneault, J.F., Parisi, F., Costante, G., Rubin, U., Banda, P., Chae, Y., Chaibub Neto, E., Dorsey, E.R., Aydın, Z., Chen, A., Elo, L.L. ORCID: https://orcid.org/0000-0001-5648-4532, Espino, C., Glaab, E. ORCID: https://orcid.org/0000-0003-3977-7469, Goan, E., Golabchi, F.N., Görmez, Y., Jaakkola, M.K., Jonnagaddala, J. ORCID: https://orcid.org/0000-0002-9912-2344, Klén, R., Li, D., McDaniel, C., Perrin, D. ORCID: https://orcid.org/0000-0002-4007-5256, Perumal, T.M., Rad, N.M., Rainaldi, E. ORCID: https://orcid.org/0000-0003-1082-7055, Sapienza, S., Schwab, P., Shokhirev, N., Venäläinen, M.S. ORCID: https://orcid.org/0000-0003-1777-4259, Vergara-Diaz, G., Zhang, Y. ORCID: https://orcid.org/0000-0002-7538-872X, Wang, Y., Guan, Y. ORCID: https://orcid.org/0000-0001-8275-2852, Brunner, D., Bonato, P. ORCID: https://orcid.org/0000-0002-1818-1714, Mangravite, L.M. ORCID: https://orcid.org/0000-0001-7841-3612 and Omberg, L. ORCID: https://orcid.org/0000-0002-4719-9120
NPJ Digital Medicine 4 (1): 53. 19 March 2021

Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Mikuda, N., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Kärgel, E., Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Tufan, A.B. ORCID: https://orcid.org/0000-0002-8734-9736, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Sun, W. ORCID: https://orcid.org/0000-0001-9607-1361, Krahn, I., Schleich, K., von Hoff, L., Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121, Willenbrock, M., Jungmann, S., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
EMBO Journal 40 (6): e104296. 15 March 2021

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M. ORCID: https://orcid.org/0000-0002-6863-841X, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Brandt, B., Lowenstein, E.D. ORCID: https://orcid.org/0000-0003-3755-0818, Schöwel, V. ORCID: https://orcid.org/0000-0002-5924-3088, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Nature Communications 11 : 6375. 11 December 2020

Single-cell analyses of aging, inflammation and senescence.
Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Palmer, D., Kowald, A., Escobar, H.M., Barrantes, I., Möller, S., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Fuellen, G.
Ageing Research Reviews 64 : 101156. December 2020

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V. ORCID: https://orcid.org/0000-0002-0077-1935, Berruezo-Llacuna, M., Altwasser, R. ORCID: https://orcid.org/0009-0002-6216-6068, Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Sundaravinayagam, D. ORCID: https://orcid.org/0000-0003-0717-7530, Balasubramanian, S. ORCID: https://orcid.org/0000-0003-1830-5737, Caganova, M. ORCID: https://orcid.org/0000-0002-4576-6574, Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Rahjouei, A. ORCID: https://orcid.org/0000-0003-3973-6333, Henke, M.T. ORCID: https://orcid.org/0000-0001-6572-1667, Driesner, M., Keller, L., Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793
Journal of Experimental Medicine 217 (10): e20200137. 5 October 2020

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors.
Möller, J. ORCID: https://orcid.org/0000-0001-8429-3784, Isbilir, A. ORCID: https://orcid.org/0000-0002-9629-1150, Sungkaworn, T., Osberg, B. ORCID: https://orcid.org/0000-0002-9854-9901, Karathanasis, C., Sunkara, V., Grushevskyi, E.O. ORCID: https://orcid.org/0000-0003-1779-8306, Bock, A. ORCID: https://orcid.org/0000-0002-6344-6494, Annibale, P. ORCID: https://orcid.org/0000-0003-3208-5347, Heilemann, M. ORCID: https://orcid.org/0000-0002-9821-3578, Schütte, C. and Lohse, M.J. ORCID: https://orcid.org/0000-0002-0599-3510
Nature Chemical Biology 16 (9): 946-954. September 2020

Deep learning for genomics using Janggu.
Kopp, W. ORCID: https://orcid.org/0000-0003-0376-0032, Monti, R. ORCID: https://orcid.org/0000-0002-6354-8319, Tamburrini, A., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Nature Communications 11 (1): 3488. 13 July 2020

Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Yasuda, T. ORCID: https://orcid.org/0000-0001-9997-6852, Ronen, J. ORCID: https://orcid.org/0000-0003-3980-6469, Wirtz, T. ORCID: https://orcid.org/0009-0005-5677-9804, Weber, T. ORCID: https://orcid.org/0000-0003-2079-842X, Sack, U., Caeser, R., Zhang, J., Li, X. ORCID: https://orcid.org/0000-0002-1173-1066, Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696, Jauch, A., Unger, K., Hodson, D.J. ORCID: https://orcid.org/0000-0001-6225-2033, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Proceedings of the National Academy of Sciences of the United States of America 117 (25): 14421-14432. 23 June 2020

Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Menegatti, J., Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Praktiknjo, S. ORCID: https://orcid.org/0000-0002-0186-5271, Walch-Rückheim, B., Bosse, J. ORCID: https://orcid.org/0000-0001-7252-5541, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Grässer, F., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
Nature Communications 10 (1): 4878. 25 October 2019

HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K. ORCID: https://orcid.org/0000-0002-5994-4802, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Bulut, S., Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Nucleic Acids Research : gkz460. 20 June 2019

Global identification of functional microRNA-mRNA interactions in Drosophila.
Wessels, H.H. ORCID: https://orcid.org/0000-0001-5551-404X, Lebedeva, S. ORCID: https://orcid.org/0000-0003-0857-8256, Hirsekorn, A., Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Mukherjee, N. ORCID: https://orcid.org/0000-0003-0017-1400 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Nature Communications 10 (1): 1626. 9 April 2019

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Schulz-Beiss, K.W., Patone, G. ORCID: https://orcid.org/0000-0002-7242-0341, Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
Blood 133 (13): 1489-1494. 28 March 2019

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. ORCID: https://orcid.org/0000-0002-8499-1387, Rom, A., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Arrey, G., Terne, M., Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Ulitsky, I. ORCID: https://orcid.org/0000-0003-0555-6561 and Chekulaeva, M. ORCID: https://orcid.org/0000-0002-6868-7887
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling.
Karabacak Calviello, A. ORCID: https://orcid.org/0000-0002-4740-7938, Hirsekorn, A., Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Yusuf, D. ORCID: https://orcid.org/0000-0001-8683-7845 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Genome Biology 20 (1): 42. 21 February 2019

Deciphering human ribonucleoprotein regulatory networks.
Mukherjee, N. ORCID: https://orcid.org/0000-0003-0017-1400, Wessels, H.H. ORCID: https://orcid.org/0000-0001-5551-404X, Lebedeva, S. ORCID: https://orcid.org/0000-0003-0857-8256, Sajek, M., Ghanbari, M. ORCID: https://orcid.org/0000-0002-6015-2968, Garzia, A., Munteanu, A. ORCID: https://orcid.org/0000-0002-6328-3947, Yusuf, D. ORCID: https://orcid.org/0000-0001-8683-7845, Farazi, T., Hoell, J.I., Akat, K.M., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Tuschl, T. and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Nucleic Acids Research 47 (2): 570-581. 25 January 2019

Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia.
James, A.R. ORCID: https://orcid.org/0000-0001-6098-2761, Schroeder, M.P., Neumann, M., Bastian, L., Eckert, C., Gökbuget, N., Tanchez, J.O., Schlee, C., Isaakidis, K., Schwartz, S., Burmeister, T., von Stackelberg, A., Rieger, M.A., Göllner, S., Horstman, M., Schrappe, M., Kirschner-Schwabe, R., Brüggemann, M., Müller-Tidow, C., Serve, H., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Baldus, C.D.
Journal of Hematology & Oncology 12 (1): 8. 14 January 2019

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N., Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Beaudette, P., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Sun, W. ORCID: https://orcid.org/0000-0001-9607-1361, Tufan, A.B. ORCID: https://orcid.org/0000-0002-8734-9736, Perder, B., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
EMBO Journal 37 (24): e98658. 14 December 2018

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Cheng, J.Y. ORCID: https://orcid.org/0000-0001-8942-0607, Russo, G., Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Rudolph, I.M. ORCID: https://orcid.org/0000-0002-3903-0755, Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Krauss, M., Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Pascual, J.M. and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Cell 175 (1): 239-253. 20 September 2018

Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Menegatti, J., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Hennig, T., Theil, K. ORCID: https://orcid.org/0000-0002-7205-6308, Rutkowski, A., Ferrai, C. ORCID: https://orcid.org/0000-0002-8088-2757, Baer, L., Kermas, L., Friedel, C. ORCID: https://orcid.org/0000-0003-3569-4877, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Dölken, L., Grässer, F. and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
Genome Biology 18 (1): 209. 31 October 2017

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A., van den Bruck, D., Ciolli Mattioli, C. ORCID: https://orcid.org/0000-0002-8499-1387, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Moreno-Estelles, M., Calviello, L. ORCID: https://orcid.org/0000-0002-5600-0988, Filipchyk, A. ORCID: https://orcid.org/0000-0002-2029-8460, Peguero-Sanchez, E. ORCID: https://orcid.org/0000-0002-8317-5572, Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Merino, E., Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Mazzoni, E.O., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Chekulaeva, M. ORCID: https://orcid.org/0000-0002-6868-7887
Nature Communications 8 (1): 583. 19 September 2017

The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy.
Grüning, B.A., Fallmann, J., Yusuf, D. ORCID: https://orcid.org/0000-0001-8683-7845, Will, S., Erxleben, A., Eggenhofer, F., Houwaart, T., Batut, B., Videm, P., Bagnacani, A., Wolfien, M., Lott, S.C., Hoogstrate, Y., Hess, W.R., Wolkenhauer, O., Hoffmann, S., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Stadler, P.F. and Backofen, R.
Nucleic Acids Research 45 (W1): W560-W566. 3 July 2017

RCAS: an RNA centric annotation system for transcriptome-wide regions of interest.
Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Yusuf, D. ORCID: https://orcid.org/0000-0001-8683-7845, Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Nucleic Acids Research 45 (10): e91. 2 June 2017

Altmüller, Janine (BIMSB/BIH)

circVDJ-seq for T cell clonotype detection in single-cell and spatial multi-omics.
Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Raspe, Raphael, Pascual-Reguant, Anna, Theurillat, Ilan ORCID: https://orcid.org/0000-0002-1125-1951, Pentimalli, Tancredi Massimo ORCID: https://orcid.org/0000-0002-8461-7918, Hsieh, Yu-Hsin ORCID: https://orcid.org/0000-0003-3037-8728, Gil, Marine ORCID: https://orcid.org/0000-0002-3885-7806, Dietrich, Carola, Seeger-Zografakis, Michaela, Quedenau, Claudia ORCID: https://orcid.org/0000-0002-6846-4915, Wilde, Jeannine, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Fischer, Cornelius ORCID: https://orcid.org/0000-0003-0329-2435, Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891, Seitz, Volkhard, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Eggert, Angelika, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Borodina, Tatiana ORCID: https://orcid.org/0000-0002-6978-016X, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Altmueller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Hauser, Anja Erika and Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295
Genome Medicine 18 (1): 84. 11 June 2026

Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection.
Pfefferkorn, Anna Maria ORCID: https://orcid.org/0000-0002-7126-9838, Jahn, Lorenz ORCID: https://orcid.org/0009-0003-4229-3059, Gauthier, Patrick T. ORCID: https://orcid.org/0000-0002-6103-8307, Kulow, Vera Anna ORCID: https://orcid.org/0000-0002-4226-6697, Roeles, Johannes, Müller-Bötticher, Niklas, Gerhardt, Louisa M.S., Leiz, Janna ORCID: https://orcid.org/0000-0002-6531-7047, Sarfraz, Sadia, Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Greite, Robert, Lovric, Svjetlana ORCID: https://orcid.org/0000-0003-3953-9794, Gamrekelashvili, Jaba ORCID: https://orcid.org/0000-0001-7533-6906, Limbourg, Florian, Schmitz, Jessica ORCID: https://orcid.org/0000-0001-9843-7339, Bräsen, Jan Hinrich ORCID: https://orcid.org/0000-0002-2863-3067, Scheffner, Irina ORCID: https://orcid.org/0000-0002-5930-1866, Sauer, Igor M. ORCID: https://orcid.org/0000-0001-9355-937X, Aigner, Felix, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Gwinner, Wilfried ORCID: https://orcid.org/0000-0003-1703-893X, Ishaque, Naveed ORCID: https://orcid.org/0000-0002-8426-901X, Fähling, Michael ORCID: https://orcid.org/0000-0003-1079-5049, Schmidt-Ott, Kai M. ORCID: https://orcid.org/0000-0002-7700-7142, Halloran, Philip F., Ashraf, Muhammad Imtiaz ORCID: https://orcid.org/0000-0002-6789-5393 and Hinze, Christian ORCID: https://orcid.org/0000-0003-2526-1621
Nature Communications 17 (1): 1060. 28 January 2026

The dorsal aortic compartment is a developmental source of brown adipose tissue in mice.
Heider, Sophie ORCID: https://orcid.org/0000-0003-4874-6971, Fischer, Cornelius ORCID: https://orcid.org/0000-0003-0329-2435, Secener, Ali Kerim ORCID: https://orcid.org/0000-0003-4806-2852, Vallecillo-Garcı́a, Pedro, Kotsaris, Georgios, Meisen, Zarah G., Pawolski, Verena, Giesecke-Thiel, Claudia ORCID: https://orcid.org/0000-0002-5927-7018, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Schulz, Tim J. ORCID: https://orcid.org/0000-0002-8413-3972, Sauer, Sascha ORCID: https://orcid.org/0000-0002-4794-3693 and Stricker, Sigmar ORCID: https://orcid.org/0000-0002-7174-5363
Nature Communications 17 (1): 286. 8 January 2026

Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation.
Harit, Kunjan, Yi, Wenjing, Jeron, Andreas, Schmidt, Jakob, Beckervordersandforth, Ruth ORCID: https://orcid.org/0000-0002-3617-7567, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Deckert, Martina, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Wang, Xu ORCID: https://orcid.org/0000-0001-8428-9339, Nishanth, Gopala ORCID: https://orcid.org/0000-0002-7280-5663 and Schlüter, Dirk ORCID: https://orcid.org/0000-0003-1478-3328
Nature Communications 16 (1): 9279. 20 October 2025

Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration.
Sekulic, Andjela, Herr, Sarah M., Mulfaul, Kelly, Pompös, Inga-Marie ORCID: https://orcid.org/0000-0001-9314-8378, Winkler, Silvia, Dietrich, Carola, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Mullins, Robert F., Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Zipfel, Peter F., Sennlaub, Florian, Skerka, Christine and Strauß, Olaf
Journal of Neuroinflammation 22 (1): 173. 3 July 2025

A macrophage-predominant immunosuppressive microenvironment and therapeutic vulnerabilities in advanced salivary gland cancer.
Zuljan, E., von der Emde, B., Piwonski, I., Pestana, A., Klinghammer, K. ORCID: https://orcid.org/0000-0001-6425-4833, Mock, A. ORCID: https://orcid.org/0000-0002-3332-9166, Horak, P. ORCID: https://orcid.org/0000-0003-4536-9306, Heining, C., Klauschen, F. ORCID: https://orcid.org/0000-0002-9131-2389, Pretzell, I., Boerries, M. ORCID: https://orcid.org/0000-0002-3670-0602, Brandts, C.H., Kreutzfeldt, S. ORCID: https://orcid.org/0000-0003-3278-4586, Teleanu, M.V., Hübschmann, D. ORCID: https://orcid.org/0000-0002-6041-7049, Morris, L.G.T. ORCID: https://orcid.org/0000-0002-4417-2280, Heiland, M. ORCID: https://orcid.org/0000-0002-4987-2913, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Glimm, H. ORCID: https://orcid.org/0000-0003-4104-1135, Fröhling, S. ORCID: https://orcid.org/0000-0001-7907-4595, Ochsenreither, S. ORCID: https://orcid.org/0000-0001-6024-4312, Keilholz, U., Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Rieke, D.T. ORCID: https://orcid.org/0000-0003-0027-7977
Nature Communications 16 (1): 5303. 12 June 2025

The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis.
Cineus, R. ORCID: https://orcid.org/0000-0003-4393-5757, Luo, Y. ORCID: https://orcid.org/0009-0003-0401-467X, Saliutina, M., Manna, S. ORCID: https://orcid.org/0000-0003-2360-0618, Cancino, C.A., Velasco Blázquez, L., Wang, L., Bösel, D., Abdelrahman, A., Klementowicz, J.E., Scherl, A., Hainbuch, S., Bréart, B., Kwon, G., Konopka, A., Guerra, G.M., von Coburg, E. ORCID: https://orcid.org/0009-0001-8546-8854, Gerbeth, Lo., Roels, J., Heinrich, F. ORCID: https://orcid.org/0000-0001-6097-5422, Müller, N. ORCID: https://orcid.org/0000-0003-1559-7711, Durek, P. ORCID: https://orcid.org/0000-0002-6179-0670, Deigendesch, N. ORCID: https://orcid.org/0000-0002-6036-3327, Ziai, J., Hung, J., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Kühl, A.A. ORCID: https://orcid.org/0000-0003-2293-5387, Wirtz, S. ORCID: https://orcid.org/0000-0001-6936-7431, Löhning, M. ORCID: https://orcid.org/0000-0001-6382-7281, Keir, M. ORCID: https://orcid.org/0000-0002-0637-4092, Diefenbach, A. ORCID: https://orcid.org/0000-0002-9176-9530, Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Siegmund, B. ORCID: https://orcid.org/0000-0002-0055-958X, Schumann, M., Romagnani, C. ORCID: https://orcid.org/0000-0002-5167-7463, West, N.R. and Hegazy, A.N. ORCID: https://orcid.org/0000-0002-2946-8251
Nature Immunology 26 (6): 837-853. June 2025

Interleukin-12 signaling drives Alzheimer’s disease pathology through disrupting neuronal and oligodendrocyte homeostasis.
Schneeberger, S., Kim, S.J. ORCID: https://orcid.org/0000-0001-8357-0073, Geesdorf, M.N., Friebel, E. ORCID: https://orcid.org/0000-0003-1419-2376, Eede, P., Jendrach, M. ORCID: https://orcid.org/0000-0002-8601-2277, Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920, Ruhwedel, T. ORCID: https://orcid.org/0000-0002-9535-9395, Hülsmeier, A.J. ORCID: https://orcid.org/0000-0001-6987-8979, Gimber, N. ORCID: https://orcid.org/0000-0001-9456-3063, Foerster, M., Obst, J., Andreadou, M. ORCID: https://orcid.org/0000-0001-6757-4664, Mundt, S. ORCID: https://orcid.org/0000-0003-2169-2109, Schmoranzer, J., Prokop, S., Kessler, W., Kuhlmann, T., Möbius, W. ORCID: https://orcid.org/0000-0002-2902-7165, Nave, K.A. ORCID: https://orcid.org/0000-0001-8724-9666, Hornemann, T. ORCID: https://orcid.org/0000-0002-4218-1087, Becher, B. ORCID: https://orcid.org/0000-0002-1541-7867, Edgar, J.M. ORCID: https://orcid.org/0000-0002-3869-0962, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917
Nature Aging 5 (4): 622-641. April 2025

Rapid brain tumor classification from sparse epigenomic data.
Brändl, B. ORCID: https://orcid.org/0000-0003-1044-1355, Steiger, M. ORCID: https://orcid.org/0000-0002-3747-685X, Kubelt, C., Rohrandt, C., Zhu, Z. ORCID: https://orcid.org/0000-0003-3779-4265, Evers, M., Wang, G., Schuldt, B., Afflerbach, A.K., Wong, D., Lum, A., Halldorsson, S., Djirackor, L., Leske, H., Magadeeva, S., Smičius, R., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Schmidt, N.O., Schüller, U. ORCID: https://orcid.org/0000-0002-8731-1121, Vik-Mo, E.O. ORCID: https://orcid.org/0000-0001-8303-4123, Proescholdt, M., Riemenschneider, M.J., Zadeh, G. ORCID: https://orcid.org/0000-0002-6637-4502, Ammerpohl, O., Yip, S. ORCID: https://orcid.org/0000-0002-8514-9861, Synowitz, M., van Bömmel, A. ORCID: https://orcid.org/0000-0002-8434-8586, Kretzmer, H. ORCID: https://orcid.org/0000-0002-0723-4980 and Müller, F.J. ORCID: https://orcid.org/0000-0001-9478-8430
Nature Medicine 31 (3): 840-848. March 2025

Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4(+) T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease.
Horn, V., Cancino, C.A., Steinheuer, L.M., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Fritz, K., Nguyen, A.L., Juhran, K.S., Plattner, C., Bösel, D., Oldenburg, L., Burns, M., Schulz, A.R., Saliutina, M., Mantzivi, E., Lissner, D., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Mashreghi, M.F., Zundler, S., Sonnenberg, E., Schumann, M., Haag, L.M., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Flatz, L., Trjanoski, Z., D'Haens, G., Weidinger, C., Mei, H.E., Siegmund, B., Thurley, K. and Hegazy, A.N.
Gastroenterology 168 (2): 327-343. February 2025

Genetic alterations, therapy response, and survival among patients with triple-negative breast cancer: a secondary analysis of a randomized clinical trial.
Richters, L., Gluz, O., Weber-Lassalle, N., Christgen, M., Haverkamp, H., Kuemmel, S., Kayali, M., Kates, R.E., Grischke, E.M., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Forstbauer, H., Thiele, H., Braun, M., Warm, M., Ossowski, A., Wuerstlein, R., Ernst, C., Graeser, M., Linn, S.C., Nitz, U., Hauke, J., Kreipe, H.H., Schmutzler, R.K., Hahnen, E. and Harbeck, N.
JAMA Network Open 8 (2): e2461639. February 2025

TERT expression and clinical outcome in pulmonary carcinoids.
Werr, L. ORCID: https://orcid.org/0000-0002-3697-4136, Bartenhagen, C. ORCID: https://orcid.org/0000-0002-2522-1454, Rosswog, C. ORCID: https://orcid.org/0000-0002-8855-6198, Cartolano, M., Voegele, C. ORCID: https://orcid.org/0000-0002-9592-8869, Sexton-Oates, A., Di Genova, A. ORCID: https://orcid.org/0000-0002-3120-9283, Ernst, A. ORCID: https://orcid.org/0000-0003-2375-1889, Kahlert, Y. ORCID: https://orcid.org/0009-0006-0556-0439, Hemstedt, N., Höppner, S. ORCID: https://orcid.org/0000-0002-2318-1874, Mansuet Lupo, A. ORCID: https://orcid.org/0000-0002-7196-2114, Pelosi, G. ORCID: https://orcid.org/0000-0003-4725-4692, Brcic, L. ORCID: https://orcid.org/0000-0002-9098-8416, Papotti, M., George, J., Bosco, G., Quaas, A., Tang, L.H., Robzyk, K., Kadota, K., Roh, M.S., Fanaroff, R.E. ORCID: https://orcid.org/0009-0000-1451-000X, Falcon, C.J. ORCID: https://orcid.org/0000-0001-9143-1639, Büttner, R. ORCID: https://orcid.org/0000-0001-8806-4786, Lantuejoul, S., Rekhtman, N. ORCID: https://orcid.org/0000-0001-5801-3144, Rudin, C.M. ORCID: https://orcid.org/0000-0001-5204-3465, Travis, W.D., Alcala, N. ORCID: https://orcid.org/0000-0002-5961-5064, Fernandez-Cuesta, L., Foll, M. ORCID: https://orcid.org/0000-0001-9006-8436, Peifer, M. ORCID: https://orcid.org/0000-0002-5243-5503, Thomas, R.K. and Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242
Journal of Clinical Oncology 43 (2): 214-225. 10 January 2025

Circulating tumor DNA sequencing for biologic classification and individualized risk stratification in patients with Hodgkin Lymphoma.
Heger, J.M. ORCID: https://orcid.org/0000-0001-9463-8504, Mammadova, L., Mattlener, J. ORCID: https://orcid.org/0000-0001-7048-0351, Sobesky, S., Cirillo, M. ORCID: https://orcid.org/0000-0001-9881-0260, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Kirst, E., Reinke, S., Klapper, W., Bröckelmann, P.J. ORCID: https://orcid.org/0000-0001-9662-9900, Ferdinandus, J. ORCID: https://orcid.org/0000-0002-3481-7997, Kaul, H., Schneider, G. ORCID: https://orcid.org/0000-0001-6175-2554, Schneider, J. ORCID: https://orcid.org/0000-0001-7163-819X, Schleifenbaum, J.K. ORCID: https://orcid.org/0000-0001-7204-3235, Ullrich, R.T., Freihammer, M., Awerkiew, S. ORCID: https://orcid.org/0000-0001-5739-319X, Lohmann, M., Klein, F. ORCID: https://orcid.org/0000-0003-1376-1792, Nürnberg, P. ORCID: https://orcid.org/0000-0002-7228-428X, Hallek, M. ORCID: https://orcid.org/0000-0002-7425-4455, Rossi, D. ORCID: https://orcid.org/0000-0002-2837-1597, Mauz-Körholz, C. ORCID: https://orcid.org/0000-0002-8205-8665, Gattenlöhner, S., Bräuninger, A., Borchmann, P. ORCID: https://orcid.org/0000-0003-3782-2158, von Tresckow, B. ORCID: https://orcid.org/0000-0003-1410-4487 and Borchmann, S.
Journal of Clinical Oncology 42 (35): 4218-4230. 10 December 2024

Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals a dynamic multilayered tissue architecture.
Patsalos, A., Halasz, L., Oleksak, D., Wei, X., Nagy, G., Tzerpos, P., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Hammers, D.W., Sweeney, H.L. and Nagy, L.
Journal of Clinical Investigation 134 (20): e173858. 15 October 2024

Intramyocardial sprouting tip cells specify coronary arterialization.
Cano, E. ORCID: https://orcid.org/0000-0003-1091-8934, Schwarzkopf, J. ORCID: https://orcid.org/0000-0001-9552-0794, Kanda, M. ORCID: https://orcid.org/0000-0003-3468-3586, Lindberg, E.L. ORCID: https://orcid.org/0000-0002-2979-433X, Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Pogontke, C. ORCID: https://orcid.org/0000-0002-9610-9822, Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
Circulation Research 135 (6): 671-684. 30 August 2024

Diagnosing recipient- vs. donor-derived posttransplant myelodysplastic neoplasm via targeted single-cell mutational profiling.
Ihlow, J., Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Vuong, L.G., Bischoff, P., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Trinks, A. ORCID: https://orcid.org/0000-0001-9983-1506, Blau, O., Behnke, A., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Wu, C.J., Westermann, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, von Brünneck, A.C., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Horst, D. and Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271
Med 6 (4): 100548. 11 April 2024

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes.
Chatzinikolaou, G. ORCID: https://orcid.org/0000-0002-0868-0683, Stratigi, K. ORCID: https://orcid.org/0000-0001-7476-6410, Siametis, A. ORCID: https://orcid.org/0000-0003-0668-7563, Goulielmaki, E. ORCID: https://orcid.org/0000-0003-1651-3137, Akalestou-Clocher, A. ORCID: https://orcid.org/0000-0002-1267-6054, Tsamardinos, I. ORCID: https://orcid.org/0000-0002-2492-959X, Topalis, P. ORCID: https://orcid.org/0000-0002-1635-4810, Austin, C., Bouwman, B.A.M. ORCID: https://orcid.org/0000-0002-9827-9497, Crosetto, N., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521 and Garinis, G.A. ORCID: https://orcid.org/0000-0002-3200-5004
Science Advances 9 (45): eadi2095. 10 November 2023

Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver.
Nikopoulou, C. ORCID: https://orcid.org/0000-0001-7982-7737, Kleinenkuhnen, N., Parekh, S. ORCID: https://orcid.org/0000-0002-4826-1651, Sandoval, T., Ziegenhain, C. ORCID: https://orcid.org/0000-0003-2208-4877, Schneider, F., Giavalisco, P. ORCID: https://orcid.org/0000-0002-4636-1827, Donahue, K.F., Vesting, A.J., Kirchner, M. ORCID: https://orcid.org/0000-0003-0276-0495, Bozukova, M., Vossen, C., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Wunderlich, T. ORCID: https://orcid.org/0000-0002-9209-3501, Sandberg, R. ORCID: https://orcid.org/0000-0001-6473-1740, Kondylis, V. ORCID: https://orcid.org/0000-0002-6970-8731, Tresch, A. ORCID: https://orcid.org/0000-0002-4146-6371 and Tessarz, P. ORCID: https://orcid.org/0000-0002-6953-9835
Nature Aging 3 (11): 1430-1445. November 2023

Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions.
Tschernoster, N. ORCID: https://orcid.org/0000-0002-6058-9342, Erger, F., Kohl, S., Reusch, B., Wenzel, A., Walsh, S., Thiele, H., Becker, C., Franitza, M., Bartram, M.P., Kömhoff, M., Schumacher, L., Kukat, C., Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Nürnberg, P., Rinschen, M.M., Driller, J.H., Pedersen, B.P., Schlingmann, K.P., Hüttel, B., Bockenhauer, D., Beck, B. and Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521
Genome Medicine 15 (1): 62. 23 August 2023

Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A. ORCID: https://orcid.org/0000-0002-1263-2078, Walter, S., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, McMurray, B.J., Sunaga-Franze, D.Y. ORCID: https://orcid.org/0000-0002-6851-9162, Xu, M., Zühlke, K., Russwurm, M., Bartolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Langanki, R., Qadri, F. ORCID: https://orcid.org/0000-0002-8500-489X, Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Patzak, A., Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Bähring, S. ORCID: https://orcid.org/0000-0001-8734-9755, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Persson, P.B., Maass, P.G. ORCID: https://orcid.org/0000-0002-2742-8301, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003
Kidney International 104 (2): 388-393. August 2023

Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang, Q., Stachelscheid, J., Bloehdorn, J., Pacholewska, A., Aszyk, C.M., Grotenhuijs, F., Müller, T.A., Onder, O., Wagle, P., Herling, C.D., Kleppe, M., Wang, Z., Coombes, K.R., Robrecht, S., Dalvi, P.S., Plosnita, B., Mayer, P., Abruzzo, L.V., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Gathof, B.S., Persigehl, T., Fischer, K., Jebaraj, B.M.C., Rienhoff, H.Y., Ecker, R.C., Zhao, Y., Bruns, C.J., Stilgenbauer, S., Elenitoba-Johnson, K.S.J., Hallek, M., Schweiger, M.R., Odenthal, M., Vasyutina, E. and Herling, M.
Blood 142 (1): 44-61. 6 July 2023

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J. ORCID: https://orcid.org/0000-0002-6432-7104, Muinjonov, B. ORCID: https://orcid.org/0000-0002-9380-8038, Rosiewicz, K.S. ORCID: https://orcid.org/0000-0002-6926-7227, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Biese, C., Schiweck, J., Chien, C. ORCID: https://orcid.org/0000-0001-8280-9513, Zocholl, D., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Alisch, M. ORCID: https://orcid.org/0009-0000-8316-6193 and Siffrin, V. ORCID: https://orcid.org/0000-0002-1532-2868
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P., Orgeur, M., Comai, G., Poehle-Kronnawitter, S., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Gloger, M. ORCID: https://orcid.org/0000-0002-3319-7642, Dumas, C.E., Giesecke-Thiel, C., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Tajbakhsh, S., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Stricker, S.
Immunity 56 (6): 1204-1219. 13 June 2023

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Li, H. ORCID: https://orcid.org/0000-0001-5677-3377, Liu, L. ORCID: https://orcid.org/0000-0002-9553-5475, Müllerke, S., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Heymann, F., Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 14 (1): 3025. 25 May 2023

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Stöber, M.C. ORCID: https://orcid.org/0000-0002-6679-5577, Xu, R. ORCID: https://orcid.org/0000-0002-5618-246X, Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Kasack, K., Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, van Leen, E. ORCID: https://orcid.org/0000-0001-9545-4803, Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Stefanova, M.E. ORCID: https://orcid.org/0000-0002-4419-2839, Hung, K.L. ORCID: https://orcid.org/0000-0002-3662-4662, Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Schmelz, K., Lodrini, M., Mundlos, S., Chang, H.Y. ORCID: https://orcid.org/0000-0002-9459-4393, Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Koche, R.P. ORCID: https://orcid.org/0000-0002-6820-5083 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Nature Genetics 55 (5): 880-890. May 2023

The genomic landscape across 474 surgically accessible epileptogenic human brain lesions.
López-Rivera, J.A., Leu, C., Macnee, M., Khoury, J., Hoffmann, L., Coras, R., Kobow, K., Bhattarai, N., Pérez-Palma, E., Hamer, H., Brandner, S., Rössler, K., Bien, C.G., Kalbhenn, T., Pieper, T., Hartlieb, T., Butler, E., Genovese, G., Becker, K., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Niestroj, L.M., Ferguson, L., Busch, R.M., Nürnberg, P., Najm, I., Blümcke, I. and Lal, D.
Brain 146 (4): 1342-1356. April 2023

Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19.
Mothes, R., Pascual-Reguant, A. ORCID: https://orcid.org/0000-0002-5042-3699, Koehler, R., Liebeskind, J., Liebheit, A. ORCID: https://orcid.org/0009-0007-6743-8313, Bauherr, S. ORCID: https://orcid.org/0000-0002-3736-3361, Philipsen, L. ORCID: https://orcid.org/0000-0001-5112-495X, Dittmayer, C., Laue, M. ORCID: https://orcid.org/0000-0002-6474-9139, von Manitius, R., Elezkurtaj, S., Durek, P., Heinrich, F. ORCID: https://orcid.org/0000-0001-6097-5422, Heinz, G.A. ORCID: https://orcid.org/0000-0002-9330-3689, Guerra, G.M., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Meinhardt, J., Ihlow, J., Radke, J. ORCID: https://orcid.org/0000-0001-9860-2007, Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917, Enghard, P., Stockmann, H. ORCID: https://orcid.org/0000-0002-0934-7620, Aschman, T. ORCID: https://orcid.org/0000-0002-2101-6146, Schneider, J. ORCID: https://orcid.org/0000-0002-0494-1022, Corman, V.M. ORCID: https://orcid.org/0000-0002-3605-0136, Sander, L.E. ORCID: https://orcid.org/0000-0002-0476-9947, Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Hocke, A.C. ORCID: https://orcid.org/0000-0002-6935-8612, Niesner, R.A. ORCID: https://orcid.org/0000-0001-8969-5432, Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397 and Hauser, A.E. ORCID: https://orcid.org/0000-0002-7725-9526
Nature Communications 14 (1): 791. 11 February 2023

Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Keil, P., Wulf, A., Kachariya, N., Reuscher, S., Hühn, K., Silbern, I., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Keller, M., Stehle, R., Zarnack, K. ORCID: https://orcid.org/0000-0003-3527-3378, Sattler, M. ORCID: https://orcid.org/0000-0002-1594-0527, Urlaub, H. ORCID: https://orcid.org/0000-0003-1837-5233 and Sträßer, K. ORCID: https://orcid.org/0000-0003-3533-5516
Nucleic Acids Research 51 (2): 831-851. 25 January 2023

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M., Mücke, M.B. ORCID: https://orcid.org/0000-0002-4957-3307, Pallien, T., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, Sholokh, A. ORCID: https://orcid.org/0000-0002-1263-2078, Schächterle, C., Aydin, A. ORCID: https://orcid.org/0000-0002-2890-0225, Kidd, A., Walter, S. ORCID: https://orcid.org/0000-0002-2041-2921, Esmati, Y. ORCID: https://orcid.org/0000-0001-9010-8119, McMurray, B.J. ORCID: https://orcid.org/0000-0003-3394-0667, Lato, D.F. ORCID: https://orcid.org/0000-0002-9263-8532, Sunaga-Franze, D.Y. ORCID: https://orcid.org/0000-0002-6851-9162, Dierks, P.H. ORCID: https://orcid.org/0000-0001-5903-8343, Flores, B.I.M., Walker-Gray, R., Gong, M. ORCID: https://orcid.org/0000-0001-7384-3429, Merticariu, C., Zühlke, K., Russwurm, M., Liu, T., Batolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Pautz, S., Schelenz, S., Taube, M., Napieczynska, H. ORCID: https://orcid.org/0000-0001-5091-1185, Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Eichhorst, J., Lehmann, M., Miller, D.C. ORCID: https://orcid.org/0000-0001-9852-677X, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Qadri, F. ORCID: https://orcid.org/0000-0002-8500-489X, Popova, E. ORCID: https://orcid.org/0000-0002-3043-9650, Langanki, R., Movsesian, M.A., Herberg, F.W. ORCID: https://orcid.org/0000-0001-7117-7653, Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Maass, P.G. ORCID: https://orcid.org/0000-0002-2742-8301, Bähring, S. ORCID: https://orcid.org/0000-0001-8734-9755, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003
Circulation 146 (23): 1758-1778. 6 December 2022

Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
Houwaart, Torsten, Belhaj, S., Tawalbeh, E., Nagels, D., Fröhlich, Y., Finzer, P., Ciruela, P., Sabrià, A., Herrero, M., Andrés, C., Antón, A., Benmoumene, A., Asskali, D., Haidar, H., von Dahlen, J., Nicolai, J., Stiller, M., Blum, J., Lange, C., Adelmann, C., Schroer, B., Osmers, U., Grice, C., Kirfel, P.P., Jomaa, H., Strelow, D., Hülse, L., Pigulla, M., Kreuzer, P., Tyshaieva, A., Weber, J., Wienemann, T., Kohns Vasconcelos, M., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Scholz, C.J., Jazmati, N., Göbels, K., Zotz, R., Pfeffer, K., Timm, J., Ehlkes, L., Walker, A. and Dilthey, A.T.
Eurosurveillance 27 (43): 2101089. 27 October 2022

Mutations in TAF8 cause a neurodegenerative disorder.
Wong, K.M. ORCID: https://orcid.org/0000-0002-5449-6318, Jepsen, W.M., Efthymiou, S., Salpietro, V., Sanchez-Castillo, M., Yip, J., Kriouile, Y., Diegmann, S. ORCID: https://orcid.org/0000-0001-9134-6303, Dreha-Kulaczewski, S., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Thiele, H., Nürnberg, P. ORCID: https://orcid.org/0000-0002-7228-428X, Toosi, M.B., Akhondian, J., Ghayoor Karimiani, E., Hummel-Abmeier, H., Huppke, B., Houlden, H. ORCID: https://orcid.org/0000-0002-2866-7777, Gärtner, J., Maroofian, R. and Huppke, P.
Brain 145 (9): 3022-3034. September 2022

Claudin-10a deficiency shifts proximal tubular Cl(-) permeability to cation selectivity via claudin-2 redistribution.
Breiderhoff, T. ORCID: https://orcid.org/0000-0002-1676-7498, Himmerkus, N. ORCID: https://orcid.org/0000-0002-2910-6728, Meoli, L. ORCID: https://orcid.org/0000-0002-9853-2624, Fromm, A. ORCID: https://orcid.org/0000-0003-4091-9612, Sewerin, S. ORCID: https://orcid.org/0000-0002-9094-9636, Kriuchkova, N. ORCID: https://orcid.org/0000-0002-9795-2440, Nagel, O. ORCID: https://orcid.org/0000-0001-6026-2676, Ladilov, Y. ORCID: https://orcid.org/0000-0002-9836-8801, Krug, S. ORCID: https://orcid.org/0000-0002-1293-2484, Quintanova, C. ORCID: https://orcid.org/0000-0001-6617-2006, Stumpp, M. ORCID: https://orcid.org/0000-0001-7765-2996, Garbe-Schönberg, D. ORCID: https://orcid.org/0000-0001-9006-9463, Westernströer, U., Merkel, C., Brinkhus, M., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Schweiger, M. ORCID: https://orcid.org/0000-0002-4672-0623, Mueller, D. ORCID: https://orcid.org/0000-0002-3478-1576, Mutig, K. ORCID: https://orcid.org/0000-0001-9006-5112, Morawski, M. ORCID: https://orcid.org/0000-0002-3817-5186, Halbritter, J. ORCID: https://orcid.org/0000-0002-1377-9880, Milatz, S. ORCID: https://orcid.org/0000-0001-9893-0473, Bleich, M. ORCID: https://orcid.org/0000-0002-1745-2295 and Günzel, D. ORCID: https://orcid.org/0000-0002-7998-7164
Journal of the American Society of Nephrology 33 (4): 699-717. April 2022

Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection clusters based on integrated genomic surveillance, outbreak analysis and contact tracing in an urban setting.
Walker, A., Houwaart, T., Finzer, P., Ehlkes, L., Tyshaieva, A., Damagnez, M., Strelow, D., Duplessis, A., Nicolai, J., Wienemann, T., Tamayo, T., Kohns Vasconcelos, M., Hülse, L., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Däumer, M.P., Thielen, A., Kolbe-Busch, S., Göbels, K., Zotz, R., Pfeffer, K., Timm, J. and Dilthey, A.T.
Clinical Infectious Diseases 74 (6): 1039-1046. 15 March 2022

A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
Patsalos, A. ORCID: https://orcid.org/0000-0002-9022-4985, Halasz, L. ORCID: https://orcid.org/0000-0003-4726-7012, Medina-Serpas, M.A. ORCID: https://orcid.org/0000-0003-0532-5413, Berger, W.K. ORCID: https://orcid.org/0000-0003-0727-7064, Daniel, B. ORCID: https://orcid.org/0000-0002-2410-8767, Tzerpos, P. ORCID: https://orcid.org/0000-0002-0398-0855, Kiss, M. ORCID: https://orcid.org/0000-0002-5649-0382, Nagy, G. ORCID: https://orcid.org/0000-0002-3273-731X, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Simandi, Z. ORCID: https://orcid.org/0000-0001-8894-1259, Varga, T. ORCID: https://orcid.org/0000-0002-5303-1850 and Nagy, L. ORCID: https://orcid.org/0000-0001-6653-2155
Journal of Experimental Medicine 219 (1): e20210420. 3 January 2022

Chromothripsis followed by circular recombination drives oncogene amplification in human cancer.
Rosswog, C., Bartenhagen, C., Welte, A. ORCID: https://orcid.org/0000-0002-3695-4856, Kahlert, Y., Hemstedt, N., Lorenz, W., Cartolano, M., Ackermann, S. ORCID: https://orcid.org/0000-0002-5869-7344, Perner, S., Vogel, W., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Nürnberg, P., Hertwig, F., Göhring, G., Lilienweiss, E., Stütz, A.M., Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794, Thomas, R.K., Peifer, M. ORCID: https://orcid.org/0000-0002-5243-5503 and Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242
Nature Genetics 53 (12): 1673–1685. December 2021

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Krämer, B., Knoll, R. ORCID: https://orcid.org/0000-0001-8320-5885, Bonaguro, L., ToVinh, M. ORCID: https://orcid.org/0000-0002-1625-9741, Raabe, J. ORCID: https://orcid.org/0000-0002-6894-1451, Astaburuaga-García, R., Schulte-Schrepping, J., Kaiser, K.M., Rieke, G.J., Bischoff, J., Monin, M.B., Hoffmeister, C. ORCID: https://orcid.org/0000-0001-6473-4087, Schlabe, S., De Domenico, E., Reusch, N. ORCID: https://orcid.org/0000-0001-5625-0701, Händler, K., Reynolds, G., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Hack, G., Finnemann, C., Nischalke, H.D., Strassburg, C.P., Stephenson, E., Su, Y., Gardner, L., Yuan, D., Chen, D., Goldman, J., Rosenstiel, P., Schmidt, S.V., Latz, E., Hrusovsky, K., Ball, A.J., Johnson, J.M., Koenig, P.A., Schmidt, F.I., Haniffa, M., Heath, J.R., Kümmerer, B.M., Keitel, V., Jensen, B., Stubbemann, P., Kurth, F., Sander, L.E., Sawitzki, B., Aschenbrenner, A.C., Schultze, J.L. and Nattermann, J.
Immunity 54 (11): 2650-2669. 9 November 2021

A comparison of metabolic labeling and statistical methods to infer genome-wide dynamics of RNA turnover.
Boileau, E., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Naarmann-de Vries, I.S. and Dieterich, C. ORCID: https://orcid.org/0000-0001-9468-6311
Briefings in Bioinformatics 22 (6): bbab219. November 2021

Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01.
Weiner, J. ORCID: https://orcid.org/0000-0003-1438-7819, Suwalski, P., Holtgrewe, M. ORCID: https://orcid.org/0000-0002-3051-1763, Rakitko, A. ORCID: https://orcid.org/0000-0003-0567-7734, Thibeault, C., Müller, M., Patriki, D., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Krüger, U., Ilinsky, V. ORCID: https://orcid.org/0000-0003-4377-2759, Popov, I., Balnis, J., Jaitovich, A., Helbig, E.T., Lippert, L.J., Stubbemann, P., Real, L.M., Macías, J., Pineda, J.A., Fernandez-Fuertes, M., Wang, X., Karadeniz, Z., Saccomanno, J., Doehn, J.M., Hübner, R.H., Hinzmann, B., Salvo, M., Blueher, A., Siemann, S., Jurisic, S., Beer, J.H., Rutishauser, J., Wiggli, B., Schmid, H., Danninger, K., Binder, R., Corman, V.M., Mühlemann, B., Arjun Arkal, R., Fragiadakis, G.K., Mick, E. ORCID: https://orcid.org/0000-0002-7299-808X, Calfee, C.S., Erle, D.J., Hendrickson, C.M., Kangelaris, K.N., Krummel, M.F., Woodruff, P.G., Langelier, C.R., Venkataramani, U., García, F., Zyla, J. ORCID: https://orcid.org/0000-0002-2895-7969, Drosten, C., Braun, A. ORCID: https://orcid.org/0000-0003-1145-0261, Jones, T.C., Suttorp, N., Witzenrath, M., Hippenstiel, S., Zemojtel, T., Skurk, C., Wolfgang, P., Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Ripke, S., Sander, L.E., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Landmesser, U., Guettouche, T., Kurth, F. and Heidecker, B.
EClinicalMedicine 40 : 101099. October 2021

Swarm Learning for decentralized and confidential clinical machine learning.
Warnat-Herresthal, S., Schultze, H., Shastry, K.L., Manamohan, S., Mukherjee, S., Garg, V., Sarveswara, R., Händler, K., Pickkers, P., Aziz, N.A., Ktena, S., Tran, F., Bitzer, M., Ossowski, S., Casadei, N., Herr, C., Petersheim, D., Behrends, U., Kern, F., Fehlmann, T., Schommers, P., Lehmann, C., Augustin, M., Rybniker, J., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Mishra, N., Bernardes, J.P., Krämer, B., Bonaguro, L., Schulte-Schrepping, J., De Domenico, E., Siever, C., Kraut, M., Desai, M., Monnet, B., Saridaki, M., Siegel, C.M., Drews, A., Nuesch-Germano, M., Theis, H., Heyckendorf, J., Schreiber, S., Kim-Hellmuth, S., Nattermann, J., Skowasch, D., Kurth, I., Keller, A., Bals, R., Nürnberg, P., Rieß, O., Rosenstiel, P., Netea, M.G., Theis, F., Mukherjee, S., Backes, M., Aschenbrenner, A.C., Ulas, T., Breteler, M.M.B., Giamarellos-Bourboulis, E.J., Kox, M., Becker, M., Cheran, S., Woodacre, M.S., Goh, E.L. and Schultze, J.L.
Nature 594 (7862): 265-270. 10 June 2021

Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder.
Griesi-Oliveira, K., Fogo, M.S., Pinto, B.G.G., Alves, A.Y., Suzuki, A.M., Morales, A.G., Ezquina, S., Sosa, O.J., Sutton, G.J., Sunaga-Franze, D.Y. ORCID: https://orcid.org/0000-0002-6851-9162, Bueno, A.P., Seabra, G., Sardinha, L., Costa, S.S., Rosenberg, C., Zachi, E.C., Sertie, A.L., Martins-de-Souza, D., Reis, E.M., Voineagu, I. and Passos-Bueno, M.R.
Molecular Psychiatry 26 (5): 1589-1605. May 2021

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C., Mouktaroudi, M., Krämer, B., Oestreich, M., Antonakos, N., Nuesch-Germano, M., Gkizeli, K., Bonaguro, L., Reusch, N., Baßler, K., Saridaki, M., Knoll, R., Pecht, T., Kapellos, T.S., Doulou, S., Kröger, C., Herbert, M., Holsten, L., Horne, A. ORCID: https://orcid.org/0000-0002-4209-4573, Gemünd, I.D., Rovina, N., Agrawal, S., Dahm, K., van Uelft, M., Drews, A., Lenkeit, L., Bruse, N., Gerretsen, J., Gierlich, J., Becker, M., Händler, K., Kraut, M., Theis, H., Mengiste, S., Domenico, E., Schulte-Schrepping, J., Seep, L., Raabe, J., Hoffmeister, C., ToVinh, M., Keitel, V., Rieke, G., Talevi, V., Skowasch, D., Aziz, N.A., Pickkers, P., van de Veerdonk, F.L., Netea, M.G., Schultze, J.L., Kox, M., Breteler, M.M.B., Nattermann, J., Koutsoukou, A., Giamarellos-Bourboulis, E.J. and Ulas, T. ORCID: https://orcid.org/0000-0002-9785-4197
Genome Medicine 13 (1): 7. 13 January 2021

Viral cGAMP nuclease reveals the essential role of DNA sensing in protection against acute lethal virus infection.
Hernáez, B. ORCID: https://orcid.org/0000-0002-4351-0102, Alonso, G. ORCID: https://orcid.org/0000-0002-9803-9370, Georgana, I. ORCID: https://orcid.org/0000-0002-8976-1177, El-Jesr, M., Martín, R., Shair, K.H.Y. ORCID: https://orcid.org/0000-0002-9556-1745, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Maluquer de Motes, C. ORCID: https://orcid.org/0000-0003-4712-4601 and Alcamí, A. ORCID: https://orcid.org/0000-0002-3333-6016
Science Advances 6 (38): eabb4565. 18 September 2020

Intronic CRISPR repair in a preclinical model of Noonan syndrome-associated cardiomyopathy.
Hanses, U., Kleinsorge, M., Roos, L., Yigit, G., Li, Y., Barbarics, B., El-Battrawy, I., Lan, H., Tiburcy, M., Hindmarsh, R., Lenz, C., Salinas, G., Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Müller, C., Adham, I., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Nürnberg, P., Paul, T., Zimmermann, W.H., Hasenfuss, G., Wollnik, B. and Cyganek, L.
Circulation 142 (11): 1059-1076. 15 September 2020

Resolving fates and single-cell transcriptomes of hematopoietic stem cell clones by PolyloxExpress barcoding.
Pei, W., Shang, F., Wang, X., Fanti, A.K., Greco, A., Busch, K., Klapproth, K., Zhang, Q., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Feyerabend, T.B., Höfer, T. and Rodewald, H.R.
Cell Stem Cell 27 (3): 383-395. 3 September 2020

Benchmarking single-cell RNA-sequencing protocols for cell atlas projects.
Mereu, E., Lafzi, A., Moutinho, C., Ziegenhain, C. ORCID: https://orcid.org/0000-0003-2208-4877, McCarthy, D.J., Álvarez-Varela, A., Batlle, E., Sagar, Grün, D. ORCID: https://orcid.org/0000-0002-3364-5898, Lau, J.K., Boutet, S.C., Sanada, C., Ooi, A., Jones, R.C. ORCID: https://orcid.org/0000-0001-7235-9854, Kaihara, K., Brampton, C., Talaga, Y., Sasagawa, Y., Tanaka, K., Hayashi, T., Braeuning, C. ORCID: https://orcid.org/0009-0007-1439-9920, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Trefzer, T. ORCID: https://orcid.org/0000-0003-2031-7470, Conrad, C., Adiconis, X., Nguyen, L.T., Regev, A. ORCID: https://orcid.org/0000-0003-3293-3158, Levin, J.Z. ORCID: https://orcid.org/0000-0002-0170-3598, Parekh, S. ORCID: https://orcid.org/0000-0002-4826-1651, Janjic, A. ORCID: https://orcid.org/0000-0001-7180-5381, Wange, L.E. ORCID: https://orcid.org/0000-0002-3275-9156, Bagnoli, J.W., Enard, W. ORCID: https://orcid.org/0000-0002-4056-0550, Gut, M., Sandberg, R. ORCID: https://orcid.org/0000-0001-6473-1740, Nikaido, I. ORCID: https://orcid.org/0000-0002-7261-2570, Gut, I. ORCID: https://orcid.org/0000-0001-7219-632X, Stegle, O. and Heyn, H. ORCID: https://orcid.org/0000-0002-3276-1889
Nature Biotechnology 38 (6): 747-755. June 2020

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Urzi, A., Vidal, R. ORCID: https://orcid.org/0000-0003-4217-2014, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Kabuss, L., Hube, I., Gazzerro, E. ORCID: https://orcid.org/0000-0003-2428-0302, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693 and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
Cell Stem Cell 26 (2): 172-186. 6 February 2020

Effects of diets high in animal or plant protein on oxidative stress in individuals with type 2 diabetes: a randomized clinical trial.
Pivovarova-Ramich, O., Markova, M., Weber, D., Sucher, S., Hornemann, S., Rudovich, N., Raila, J., Sunaga-Franze, D. ORCID: https://orcid.org/0000-0002-6851-9162, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Rohn, S., Pfeiffer, A.F.H. and Grune, T.
Redox Biology 29 (2): 101397. January 2020

R-spondin-3 induces secretory, antimicrobial Lgr5(+) cells in the stomach.
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Del Mar Reinés, M., Müllerke, S., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Kapalczynska, M., Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Bakker, E.R.M., Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Rothenberg, M.E., Wiedenmann, B., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693 and Meyer, T.F. ORCID: https://orcid.org/0000-0002-6120-8679
Nature Cell Biology 21 (7): 812-823. July 2019

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.
Hernáez, B., Alonso-Lobo, J.M., Montanuy, I., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Sigal, L., Sevilla, N. and Alcamí, A.
Nature Communications 9 (1): 5440. 21 December 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais, F., Margaritte-Jeannin, P., Barnes, K.C., Cookson, W.O.C., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Ang, W., Barr, R.G., Beaty, T.H., Becker, A.B., Beilby, J., Bisgaard, H., Bjornsdottir, U.S., Bleecker, E., Bonnelykke, K., Boomsma, D.I., Bouzigon, E., Brightling, C.E., Brossard, M., Brusselle, G.G., Burchard, E., Burkart, K.M., Bush, A., Chan-Yeung, M., Chung, K.F., Couto Alves, A., Curtin, J.A., Custovic, A., Daley, D., de Jongste, J.C., Del-Rio-Navarro, B.E., Donohue, K.M., Duijts, L., Eng, C., Eriksson, J.G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M.A., Freidin, M.B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S.A, Gilliland, F., Granell, R., Graves, P.E., Gudbjartsson, D.F., Haahtela, T., Heckbert, S.R., Heederik, D., Heinrich, J., Helioevaara, M., Henderson, J., Himes, B.E., Hirose, H., Hirschhorn, J.N., Hofman, A., Holt, P., Hottenga, J., Hudson, T.J., Hui, J., Imboden, M., Ivanov, V., Jaddoe, V.W.V., James, A., Janson, C., Jarvelin, M.R., Jarvis, D., Jones, G., Jonsdottir, I., Jousilahti, P., Kabesch, M., Kähönen, M., Kantor, D.B., Karunas, A.S., Khusnutdinova, E., Koppelman, G.H., Kozyrskyj, A.L., Kreiner, E., Kubo, M., Kumar, R., Kumar, A., Kuokkanen, M., Lahousse, L., Laitinen, T., Laprise, C., Lathrop, M., Lau, S., Lee, Y.A. ORCID: https://orcid.org/0000-0002-1817-9163, Lehtimaeki, T., Letort, S., Levin, A.M., Li, G., Liang, L., Loehr, L.R., London, S.J., Loth, D.W., Manichaikul, A., Marenholz, I. ORCID: https://orcid.org/0009-0007-6933-3849, Martinez, F.J., Matheson, M.C., Mathias, R.A., Matsumoto, K., Mbarek, H., McArdle, W.L., Melbye, M., Melen, E., Meyers, D., Michel, S., Mohamdi, H., Musk, A.W., Myers, R.A., Nieuwenhuis, M.A.E., Noguchi, E., O'Connor, G.T., Ogorodova, L.M., Palmer, C.D., Palotie, A., Park, J.E., Pennell, C.E., Pershagen, G., Polonikov, A., Postma, D.S., Probst-Hensch, N., Puzyrev, V.P., Raby, B.A., Raitakari, O.T., Ramasamy, A., Rich, S.S., Robertson, C.F., Romieu, I., Salam, M.T., Salomaa, V., Schluenssen, V., Scott, R., Selivanova, P.A., Sigsgaard, T., Simpson, A., Siroux, V., Smith, L.J., Solodilova, M., Standl, M., Stefansson, K., Strachan, D.P., Stricker, B.H., Takahashi, A., Thompson, P.J., Thorleifsson, G., Thorsteinsdottir, U., Tiesler, C.M.T., Torgerson, D.G., Tsunoda, T., Uitterlinden, A.G., van der Valk, R.J.P., Vaysse, A., Vedantam, S., von Berg, A., von Mutius, E., Vonk, J.M., Waage, J., Wareham, N.J., Weiss, S.T., White, W.B., Wickman, M., Widén, E., Willemsen, G., Williams, L.K., Wouters, I.M., Yang, J.J., Zhao, J.H., Moffatt, M.F., Ober, C. and Nicolae, D.L.
Nature Genetics 50 (1): 42-53. January 2018

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Pei, W., Feyerabend, T.B., Rössler, J., Wang, X. ORCID: https://orcid.org/0000-0002-7572-6354, Postrach, D., Busch, K., Rode, I., Klapproth, K., Dietlein, N., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Wolf, S., Höfer, T. and Rodewald, H.Re.
Nature 548 (7668): 456-460. 24 August 2017

Andrade Navarro, Miguel

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N. ORCID: https://orcid.org/0000-0002-1583-2454, Naumann, H. ORCID: https://orcid.org/0000-0003-3883-0432, Ruzittu, S., Mah, N., Pongrac, I.M., Cozzitorto, C. ORCID: https://orcid.org/0000-0002-8328-4728, Hommel, A., Andrade-Navarro, M.A., Bonifacio, E. and Spagnoli, F.M. ORCID: https://orcid.org/0000-0001-7094-8188
Nature Communications 8 : 14127. 13 February 2017

Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke, M., Bounab, Y., Strempel, N., Klockmeier, K., Yigit, S., Friedrich, R.P., Chaurasia, G., Li, S., Hesse, F. ORCID: https://orcid.org/0000-0002-3320-8284, Riechers, S.P. ORCID: https://orcid.org/0000-0001-6933-9174, Russ, J. ORCID: https://orcid.org/0000-0001-6550-761X, Nicoletti, C., Boeddrich, A. ORCID: https://orcid.org/0000-0001-9118-050X, Wiglenda, T. ORCID: https://orcid.org/0000-0002-8460-9459, Haenig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Schnoegl, S., Fournier, D., Graham, R.K., Hayden, M.R., Sigrist, S., Bates, G.P., Priller, J. ORCID: https://orcid.org/0000-0001-7596-0979, Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711, Futschik, M.E. ORCID: https://orcid.org/0000-0002-6245-8071 and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Genome Research 25 (5): 701-713. May 2015

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K., Ullrich, F. ORCID: https://orcid.org/0000-0002-1153-2040, Muench, J., Lazarow, K., Lutter, D. ORCID: https://orcid.org/0000-0002-2190-8371, Mah, N. ORCID: https://orcid.org/0000-0002-1240-8076, Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Stauber, T. ORCID: https://orcid.org/0000-0003-0727-6109 and Jentsch, T.J. ORCID: https://orcid.org/0000-0002-3509-2553
Science 344 (6184): 634-638. 9 May 2014

Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence.
Rodríguez-Seguel, E., Mah, N. ORCID: https://orcid.org/0000-0002-1240-8076, Naumann, H. ORCID: https://orcid.org/0000-0003-3883-0432, Pongrac, I.M., Cerdá-Esteban, N. ORCID: https://orcid.org/0000-0002-1583-2454, Fontaine, J.F. ORCID: https://orcid.org/0000-0002-1101-4091, Wang, Y., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711 and Spagnoli, F.M. ORCID: https://orcid.org/0000-0001-7094-8188
Genes & Development 27 (17): 1932-1946. 1 September 2013