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Abdelilah-Seyfried, Salim |
Akalin, Altuna (BIMSB) |
Altmüller, Janine (BIMSB/BIH) |
Andrade Navarro, Miguel |
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Bader, Michael |
Bargou, Ralf C. |
Behlke, Joachim |
Beisaw, Arica (HI-TAC) |
Bergmann, Martin W. |
Besser, Daniel |
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Birchmeier, Walter |
Birchmeier-Kohler, Carmen |
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Blankenstein, Thomas |
Boschmann, Michael (ECRC) |
Britsch, Stefan |
Bullinger, Lars |
Bunina, Daria |
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Böttcher, Chotima (ECRC) |
Calkhoven, Cornelis F. |
Cardoso, Cristina |
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Chen, Wei (BIMSB/BIH) |
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Daniel, Peter |
Daumke, Oliver |
De la Rosa, Kathrin |
Deubzer, Hedwig (ECRC) |
Di Virgilio, Michela |
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Doerken, Bernd (MDC/ECRC) |
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Fielitz, Jens (ECRC) |
Forslund, Sofia (MDC/ECRC) |
Ganten, Detlev |
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Henssen, Anton (MDC/ECRC) |
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Hoepken, Uta |
Huebner, Norbert |
Huppa, Johannes |
Hörnberg, Hanna |
Ibanez-Tallon, Ines |
Infante-Duarte, Carmen (ECRC) |
Ivics, Zoltan |
Izsvak, Zsuzsanna |
Janz, Martin / Mathas, Stephan (MDC/ECRC) |
Jentsch, Thomas |
Jordan, Jens |
Junker, Jan Philipp (BIMSB) |
Kainmüller, Dagmar |
Kaminski, Michael (BIMSB) |
Kaplan, Oktay |
Keller, Ulrich |
Kemmner, Wolfgang |
Kempa, Stefan (BIMSB) |
Kempermann, Gerd |
Kettenmann, Helmut |
Kettritz, Ralph (ECRC) |
Kirwan, Jennifer (MDC/BIH) |
Klaassen, Sabine (ECRC) |
Klussmann, Enno |
Koehler, Matthias |
Krappmann, Daniel |
Krause, Ernst-Georg |
Kudryashev, Mikhail |
Kuehn, Ralf (MDC/BIH) |
Kunz, Severine |
Lacadie, Scott |
Landthaler, Markus (BIMSB) |
Le Noble, Ferdinand |
Lee, Young-Ae (MDC/ECRC) |
Leonhardt, Heinrich |
Leutz, Achim |
Lewin, Gary |
Lipp, Martin |
Loewer, Alexander (BIMSB) |
Lohse, Martin |
Ludwig, Leif (MDC/BIMSB/BIH) |
Luft, Friedrich C. (MDC/ECRC) |
Lupianez, Dario (BIMSB) |
Meier, Jochen |
Mertins, Philipp (MDC/BIH) |
Metzger, Jakob (BIMSB) |
Meyer, Irmtraud (BIMSB) |
Mittnenzweig, Markus (BIMSB) |
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Mueller, Dominik N. / Dechend, Ralph (MDC/ECRC) |
Mähler, Anja (ECRC) |
Na, Il-Kang (ECRC) |
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Nuernberg, Peter |
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Oertel, Frederike Cosima (ECRC) |
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Paul, Friedemann (ECRC) |
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Preibisch, Stephan (BIMSB) |
Preissner, Robert |
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Rajewsky, Nikolaus (BIMSB) |
Rathjen, Fritz G. |
Rehm, Armin |
Reich, Jens |
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Robson, Michael (BIMSB) |
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Rybak-Wolf, Agnieszka (BIMSB) |
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Sanders, Ashley (MDC/BIMSB/BIH) |
Sattentau, Quentin James |
Sauer, Sascha (BIMSB/BIH) |
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Schiattarella, Gabriele G. |
Schmidt, Deborah |
Schmidt-Ott, Kai |
Schmitt, Clemens |
Schmitz, Dietmar |
Schreiber, Adrian (ECRC) |
Schroeder, Bjoern Christian |
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Schulz-Menger, Jeanette (ECRC) |
Schwarz, Roland (BIMSB) |
Selbach, Matthias |
Sieweke, Michael |
Siffrin, Volker (ECRC) |
Sigal, Michael (BIMSB) |
Simon, Katja |
Singhal, Mahak (HI-TAC) |
Sklenar, Heinz |
Sommer, Thomas |
Spagnoli, Francesca |
Sperling, Silke (ECRC) |
Sporbert, Anje |
Spranger, Joachim (ECRC) |
Spuler, Simone (ECRC) |
Staroßom, Sarah-Christin (ECRC) |
Stein, Ulrike (MDC/ECRC) |
Sugimoto, Yoichiro |
Thierfelder, Ludwig |
Treier, Mathias |
Tursun, Baris (BIMSB) |
Uckert, Wolfgang |
Van den Hoogenhof, Maarten (HI-TAC) |
Von Kries, Jens Peter / Nazaré, Marc |
Wallukat, Gerd |
Walther, Wolfgang |
Wang, Jichang |
Wanker, Erich |
Welfle, Heinz |
Wilck, Nicola (ECRC) |
Willnow, Thomas E. |
Wittmann-Liebold, Brigitte |
Woehler, Andrew (BIMSB) |
Wolf, Jana |
Wolf, Susanne |
Zampieri, Niccolo |
Zenke, Martin |
Ziebold, Ulrike |
Zimmermann, Hanna (ECRC) |
Zinzen, Robert (BIMSB) |
Zipp, FraukeAbdelilah-Seyfried, Salim
Unilateral dampening of Bmp activity by Nodal generates cardiac left-right asymmetry.
Veerkamp, J., Rudolph, F., Cseresnyes, Z.
ORCID: https://orcid.org/0000-0002-6574-2588, Priller, F., Otten, C.
ORCID: https://orcid.org/0000-0002-8230-7350, Renz, M., Schaefer, L. and Abdelilah-Seyfried, S.
ORCID: https://orcid.org/0000-0003-3183-3841
Developmental Cell 24
(6): 660-667.
25 March 2013
Bmp signaling exerts opposite effects on cardiac differentiation.
de Pater, E., Ciampricotti, M., Priller, F., Veerkamp, J., Strate, I., Smith, K., Lagendijk, A.K., Schilling, T.F., Herzog, W., Abdelilah-Seyfried, S.
ORCID: https://orcid.org/0000-0003-3183-3841, Hammerschmidt, M. and Bakkers, J.
Circulation Research 110
(4): 578-587.
17 February 2012
Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Lange, M., Kaynak, B., Foerster, U.B., Toenjes, M., Fischer, J.J., Grimm, C., Schlesinger, J.
ORCID: https://orcid.org/0009-0005-5310-9717, Just, S., Dunkel, I., Krueger, T., Mebus, S., Lehrach, H., Lurz, R., Gobom, J., Rottbauer, W., Abdelilah-Seyfried, S.
ORCID: https://orcid.org/0000-0003-3183-3841 and Sperling, S.
ORCID: https://orcid.org/0000-0002-7135-3298
Genes & Development 22
(17): 2370-2384.
1 September 2008
Akalin, Altuna (BIMSB)
Multiplexed biomarkers dynamically detect heterogeneous residual neuroblastoma cell clone activity in the bone marrow niche.
Schroeer, Anna M., Winkler, Annika, Fillies, Marion, Kranig, Charleen, Karaman, Eliz, von Stetten, Felix, Zengerle, Roland, Lehnert, Michael, Blume, Alexander
ORCID: https://orcid.org/0000-0003-3045-8234, Hollander, Jan F., Lodrini, Marco, Eggert, Angelika, Akalin, Altuna
ORCID: https://orcid.org/0000-0002-0468-0117, Astrahantseff, Kathy, Eckert, Cornelia, Deubzer, Hedwig E.
ORCID: https://orcid.org/0000-0002-6115-4893 and Szymansky, Annabell
ORCID: https://orcid.org/0000-0003-4797-4526
Cancer Letters 645
: 218352.
1 May 2026
Multiomic and longitudinal dissection of immune dynamics associated with Parkinsonism after ciltacabtagene autoleucel therapy.
Kadel, Sofie-Katrin, Scheller, Lukas, Leipold, Alexander M., Krammer, Tobias, Raskó, Tamás, Alb, Miriam, Weis, Philipp, Leberzammer, Maria, Schmitt, Friederike, Stetter, Clara, Tamamushi, Yoko, Köck, Alicia, Köberle, Philipp, Reich, Martin, Musacchio, Thomas, Doppler, Kathrin, Sommer, Claudia, Cebulla, Nadine, McFleder, Rhonda, Ip, Chi Wang, Volkmann, Jens, Kallius, Matthias, Serfling, Sebastian E., Hartrampf, Philipp E., Buck, Andreas K., Pande, Amit
ORCID: https://orcid.org/0009-0008-0826-973X, Löffler, Dennis, Gernert, Michael, Duell, Johannes, Topp, Max S., Mersi, Julia, Waldschmidt, Johannes, Einsele, Hermann, Hudecek, Michael, Saliba, Antoine-Emmanuel, Rasche, Leo and Kortüm, K. Martin
Blood Cancer Discovery
26 March 2026
(In Press)
Flexynesis: a deep learning toolkit for bulk multi-omics data integration for precision oncology and beyond.
Uyar, Bora
ORCID: https://orcid.org/0000-0002-3170-4890, Savchyn, Taras, Naghsh Nilchi, Amirhossein
ORCID: https://orcid.org/0000-0003-1329-3044, Sarigun, Ahmet
ORCID: https://orcid.org/0009-0003-2715-5344, Wurmus, Ricardo
ORCID: https://orcid.org/0009-0003-0140-4189, Shaik, Mohammed Maqsood, Grüning, Björn
ORCID: https://orcid.org/0000-0002-3079-6586, Franke, Vedran
ORCID: https://orcid.org/0000-0003-3606-6792 and Akalin, Altuna
ORCID: https://orcid.org/0000-0002-0468-0117
Nature Communications 16
: 8261.
12 September 2025
Evaluating large language model workflows in clinical decision support for triage and referral and diagnosis.
Gaber, F.
ORCID: https://orcid.org/0009-0004-5512-8527, Shaik, M., Allega, F., Bilecz, A.J., Busch, F., Goon, K., Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792 and Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117
NPJ Digital Medicine 8
(1): 263.
9 May 2025
Enhancing biomarker based oncology trial matching using large language models.
Al Khoury, N., Shaik, M., Wurmus, R.
ORCID: https://orcid.org/0009-0003-0140-4189 and Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117
NPJ Digital Medicine 8
(1): 250.
6 May 2025
Herpesviruses mimic zygotic genome activation to promote viral replication.
Neugebauer, E., Walter, S., Tan, J., Drayman, N., Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, van Gent, M., Pennisi, S., Veratti, P., Stein, K.S., Welker, I., Tay, S., Verjans, G.M.G.M., Timmers, H.T.M., Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, Landthaler, M.
ORCID: https://orcid.org/0000-0002-1075-8734, Ensser, A., Wyler, E.
ORCID: https://orcid.org/0000-0002-9884-1806 and Full, F.
Nature Communications 16
(1): 710.
16 January 2025
Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T.
ORCID: https://orcid.org/0000-0002-9075-103X, Meyer, K.
ORCID: https://orcid.org/0000-0002-8244-6887, Roske, Y.
ORCID: https://orcid.org/0000-0001-6237-388X, Uyar, B.
ORCID: https://orcid.org/0000-0002-3170-4890, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, Imami, K.
ORCID: https://orcid.org/0000-0002-7451-4982, Ishihama, Y., Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414 and Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751
Nature Communications 15
(1): 3146.
11 April 2024
The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation.
Benedum, J.
ORCID: https://orcid.org/0000-0003-4475-7577, Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, Appel, L.M.
ORCID: https://orcid.org/0000-0002-6769-0777, Walch, L., Bruno, M.
ORCID: https://orcid.org/0000-0002-8401-7744, Schneeweiss, R., Gruber, J., Oberndorfer, H., Frank, E., Strobl, X., Polyansky, A.
ORCID: https://orcid.org/0000-0002-1011-2706, Zagrovic, B.
ORCID: https://orcid.org/0000-0003-3814-3675, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117 and Slade, D.
ORCID: https://orcid.org/0000-0002-0052-5910
Nature Communications 14
(1): 7912.
30 November 2023
Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Cauchy, P.
ORCID: https://orcid.org/0000-0002-0659-0799, Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, Giefing, M., Fornes, O.
ORCID: https://orcid.org/0000-0002-5969-3054, Vankadari, N.
ORCID: https://orcid.org/0000-0001-9363-080X, Assi, S.A., Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Weniger, M.A., Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, Anagnostopoulos, I.
ORCID: https://orcid.org/0000-0002-5043-6043, Bukur, T., Casarotto, M.G.
ORCID: https://orcid.org/0000-0002-0571-7671, Damm, F.
ORCID: https://orcid.org/0000-0001-5553-1173, Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414, Edginton-White, B., Gebhardt, J.C.M.
ORCID: https://orcid.org/0000-0003-1900-600X, Grau, M., Grunwald, S.
ORCID: https://orcid.org/0000-0003-3978-6277, Hansmann, M.L., Hartmann, S.
ORCID: https://orcid.org/0000-0003-3424-1091, Huber, L., Kärgel, E., Lusatis, S., Noerenberg, D., Obier, N., Pannicke, U.
ORCID: https://orcid.org/0000-0002-0929-1794, Fischer, A.
ORCID: https://orcid.org/0000-0002-7145-2544, Reisser, A., Rosenwald, A., Schwarz, K.
ORCID: https://orcid.org/0000-0003-3178-5990, Sundararaj, S., Weilemann, A.
ORCID: https://orcid.org/0009-0001-1340-6486, Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Xu, W., Lenz, G.
ORCID: https://orcid.org/0000-0002-4728-1693, Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370, Wasserman, W.W.
ORCID: https://orcid.org/0000-0001-6098-6412, Cockerill, P.N.
ORCID: https://orcid.org/0000-0002-4410-8174, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Siebert, R., Küppers, R., Grosschedl, R.
ORCID: https://orcid.org/0000-0002-0058-1250, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Bonifer, C.
ORCID: https://orcid.org/0000-0002-4267-0825 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Nature Communications 14
(1): 6947.
7 November 2023
The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M.
ORCID: https://orcid.org/0000-0002-6769-0777, Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, Benedum, J.
ORCID: https://orcid.org/0000-0003-4475-7577, Grishkovskaya, I.
ORCID: https://orcid.org/0000-0003-0164-9373, Strobl, X., Polyansky, A.
ORCID: https://orcid.org/0000-0002-1011-2706, Ammann, G.
ORCID: https://orcid.org/0000-0003-2135-058X, Platzer, S.
ORCID: https://orcid.org/0000-0002-2518-6273, Neudolt, A.
ORCID: https://orcid.org/0000-0002-5298-1205, Wunder, A., Walch, L., Kaiser, S., Zagrovic, B.
ORCID: https://orcid.org/0000-0003-3814-3675, Djinovic-Carugo, K.
ORCID: https://orcid.org/0000-0003-0252-2972, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117 and Slade, D.
ORCID: https://orcid.org/0000-0002-0052-5910
Nature Communications 14
(1): 166.
11 January 2023
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Cui, C., Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414, Del Bel, K.L., Eibel, H., Feng, X., Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, Gebhardt, J.C.M., Götz, A., Grunwald, S.
ORCID: https://orcid.org/0000-0003-3978-6277, Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Xiong, E., Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Rosenzweig, S.D., Schwarz, K., Turvey, S.E. and Wang, J.Y.
Science Immunology 8
(79): eade7953.
January 2023
Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D.
ORCID: https://orcid.org/0000-0001-5948-0932, Hörtenhuber, M.
ORCID: https://orcid.org/0000-0002-5599-5565, Balwierz, P.J.
ORCID: https://orcid.org/0000-0002-1548-4605, Zehnder, T.
ORCID: https://orcid.org/0000-0002-4127-2673, Mukarram, A.K., Nepal, C., Várnai, C.
ORCID: https://orcid.org/0000-0003-0048-9507, Hadzhiev, Y.
ORCID: https://orcid.org/0000-0002-1134-4904, Jimenez-Gonzalez, A.
ORCID: https://orcid.org/0000-0001-7702-6135, Li, N.
ORCID: https://orcid.org/0000-0002-8919-2357, Wragg, J., D'Orazio, F.M., Relic, D.
ORCID: https://orcid.org/0000-0001-6237-3345, Pachkov, M.
ORCID: https://orcid.org/0000-0001-7616-6435, Díaz, N.
ORCID: https://orcid.org/0000-0002-0319-3448, Hernández-Rodríguez, B.
ORCID: https://orcid.org/0000-0002-5118-8715, Chen, Z.
ORCID: https://orcid.org/0000-0002-8376-7367, Stoiber, M., Dong, M.
ORCID: https://orcid.org/0000-0003-4084-3099, Stevens, I.
ORCID: https://orcid.org/0000-0003-3823-1499, Ross, S.E., Eagle, A., Martin, R., Obasaju, O.
ORCID: https://orcid.org/0000-0001-5952-3103, Rastegar, S.
ORCID: https://orcid.org/0000-0003-4411-5646, McGarvey, A.C.
ORCID: https://orcid.org/0000-0003-3838-1139, Kopp, W.
ORCID: https://orcid.org/0000-0003-0376-0032, Chambers, E.
ORCID: https://orcid.org/0000-0003-1252-8059, Wang, D.
ORCID: https://orcid.org/0000-0003-0068-1005, Kim, H.R., Acemel, R.D.
ORCID: https://orcid.org/0000-0003-4120-0140, Naranjo, S.
ORCID: https://orcid.org/0000-0002-4529-3332, Łapiński, M.
ORCID: https://orcid.org/0000-0003-4892-976X, Chong, V.
ORCID: https://orcid.org/0000-0002-2547-3694, Mathavan, S., Peers, B., Sauka-Spengler, T.
ORCID: https://orcid.org/0000-0001-9289-0263, Vingron, M.
ORCID: https://orcid.org/0000-0002-1765-4241, Carninci, P.
ORCID: https://orcid.org/0000-0001-7202-7243, Ohler, U.
ORCID: https://orcid.org/0000-0002-0881-3116, Lacadie, S.A.
ORCID: https://orcid.org/0000-0002-0893-5340, Burgess, S.M.
ORCID: https://orcid.org/0000-0003-1147-0596, Winata, C.
ORCID: https://orcid.org/0000-0002-7718-5248, van Eeden, F.
ORCID: https://orcid.org/0000-0003-3483-8269, Vaquerizas, J.M.
ORCID: https://orcid.org/0000-0002-6583-6541, Gómez-Skarmeta, J.L.
ORCID: https://orcid.org/0000-0001-5125-4332, Onichtchouk, D.
ORCID: https://orcid.org/0000-0001-6497-1445, Brown, B.J.
ORCID: https://orcid.org/0000-0002-5898-5848, Bogdanovic, O.
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Nature Communications 11
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Instability of circular RNAs in clinical tissue samples impairs their reliable expression analysis using RT-qPCR: from the myth of their advantage as biomarkers to reality.
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Nature Communications 11
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Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients.
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Nature Communications 11
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Nature Communications 9
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Nature Medicine 24
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Nature Cell Biology 18
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Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways.
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Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.
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Journal of Experimental Medicine 210
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26 August 2013
Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.
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EMBO Journal 32
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Genes & Development 26
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1 August 2012
Targeting MET in cancer: rationale and progress.
Gherardi, E., Birchmeier, W.
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Nature Reviews Cancer 12
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BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H., Wiese, M., Zatula, N., Grigoryan, T., Dai, Y., Fritzmann, J. and Birchmeier, W.
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Gastroenterology 141
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October 2011
Stem cells: Orphan receptors find a home.
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Nature 476
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Reciprocal requirements for EDA/EDAR/NF-κB and Wnt/β-catenin signaling pathways in hair follicle induction.
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A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
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Gastroenterology 137
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MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
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Nature Medicine 15
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Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
Grigoryan, T., Wend, P., Klaus, A.
ORCID: https://orcid.org/0000-0002-1164-3322 and Birchmeier, W.
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Genes & Development 22
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1 September 2008
Wnt signalling and its impact on development and cancer.
Klaus, A.
ORCID: https://orcid.org/0000-0002-1164-3322 and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Nature Reviews Cancer 8
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May 2008
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
Malanchi, I., Peinado, H., Kassen, D., Hussenet, T., Metzger, D., Chambon, P., Huber, M., Hohl, D., Cano, A., Birchmeier, W.
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Nature 452
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3 April 2008
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Jeannet, G., Scheller, M., Scarpellino, L., Duboux, S., Gardiol, N., Back, J., Kuttler, F., Malanchi, I., Birchmeier, W.
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ORCID: https://orcid.org/0000-0001-8259-927X, Huelsken, J. and Held, W.
Blood 111
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The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer.
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ORCID: https://orcid.org/0000-0003-2884-0231, Smith, J., Waldman, T., Harris, E.D., Mertins, S.D., Heizmann, C.W., Allard, D., Birchmeier, W.
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Gastroenterology 131
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Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
Scheller, M., Huelsken, J., Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421, Taketo, M.M., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Tenen, D.G. and Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X
Nature Immunology 7
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October 2006
Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism.
MacRae, C.A., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829 and Thierfelder, L.
Journal of Clinical Investigation 116
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July 2006
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin.
Brembeck, F.H., Rosario, M. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Current Opinion in Genetics & Development 16
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February 2006
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl, U.
ORCID: https://orcid.org/0000-0003-2500-3585, Worm, U., Lalowski, M., Haenig, C.
ORCID: https://orcid.org/0000-0003-1973-7646, Brembeck, F.H., Goehler, H., Stroedicke, M., Zenkner, M., Schoenherr, A., Koeppen, S., Timm, J., Mintzlaff, S., Abraham, C., Bock, N., Kietzmann, S., Goedde, A., Toksoez, E., Droege, A., Krobitsch, S., Korn, B., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Lehrach, H. and Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630
Cell 122
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23 September 2005
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.
Hill, T.P., Spaeter, D., Taketo, M.M., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829 and Hartmann, C.
Developmental Cell 8
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1 May 2005
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
Schuetz, G.
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Journal of Cell Biology 167
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6 December 2004
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Wichter, T., Paul, M., Basson, C.T., McDermott, D.A., Lerman, B.B., Markowitz, S.M., Ellinor, P.T., MacRae, C.A., Peters, S., Grossmann, K.S., Drenckhahn, J.
ORCID: https://orcid.org/0000-0001-8347-7696, Michely, B., Sasse-Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Dietz, R., Breithardt, G., Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36
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November 2004
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
Grossmann, K.S., Grund, C., Huelsken, J., Behrend, M., Erdmann, B., Franke, W.W. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Journal of Cell Biology 167
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11 October 2004
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Brembeck, F.H., Schwarz-Romond, T., Bakkers, J., Wilhelm, S., Hammerschmidt, M. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Genes & Development 18
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15 September 2004
Making tubes: Step by step.
Rosario, M. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Developmental Cell 7
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1 July 2004
Met, metastasis, motility and more.
Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4
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December 2003
Role of β-catenin in synaptic vesicle localization and presynaptic assembly.
Bamji, S.X., Shimazu, K., Kimes, N., Huelsken, J., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Lu, B. and Reichardt, L.F.
Neuron 40
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November 2003
How to make tubes: signaling by the Met receptor tyrosine kinase.
Rosario, M. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Trends in Cell Biology 13
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June 2003
Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response.
Churin, Y., Al Ghoul, L., Kepp, O., Meyer, T.E., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829 and Naumann, M.
Journal of Cell Biology 161
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28 April 2003
Genetic interaction between Wnt/β-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Soshnikova, N., Zechner, D.
ORCID: https://orcid.org/0000-0002-2075-7540, Huelsken, J., Mishina, Y., Behringer, R.R., Taketo, M.M., Crenshaw, E.B. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Genes & Development 17
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1 January 2003
Deletion of beta-catenin impairs T cell development.
Xu, Y., Banerjee, D., Huelsken, J., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829 and Sen, J.M.
Nature Immunology 4
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1 January 2003
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.
Schwarz-Romond, T., Asbrand, C., Bakkers, J., Kuehl, M., Schaeffer, H.J.
ORCID: https://orcid.org/0000-0003-2010-9153, Huelsken, J., Behrens, J., Hammerschmidt, M. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Genes & Development 16
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15 August 2002
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.
Fujita, Y., Krause, G., Scheffner, M., Zechner, D.
ORCID: https://orcid.org/0000-0002-2075-7540, Leddy, H.E.M., Behrens, J., Sommer, T. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Nature Cell Biology 4
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1 March 2002
New aspects of Wnt signaling pathways in higher vertebrates.
Huelsken, J. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Current Opinion in Genetics & Development 11
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1 October 2001
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
Grimm, J., Sachs, M., Britsch, S.
ORCID: https://orcid.org/0000-0003-4379-3322, Di Cesare, S., Schwarz-Romond, T. and Birchmeier, W.
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Journal of Cell Biology 154
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23 July 2001
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G. and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Cell 105
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Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
Keilhack, H., Mueller, M., Boehmer, S.A., Frank, C., Weidner, K.M., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Ligensa, T., Berndt, A., Kosmehl, H., Gunther, B., Mueller, T., Birchmeier, C.
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Journal of Cell Biology 152
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22 January 2001
E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice.
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ORCID: https://orcid.org/0000-0002-8499-1387, Franke, V.
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ORCID: https://orcid.org/0000-0002-7806-2063, Moreno-Estelles, M., Calviello, L.
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ORCID: https://orcid.org/0000-0001-8096-1853, Woehler, A.
ORCID: https://orcid.org/0000-0001-5157-9313, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Merino, E., Rajewsky, N.
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ORCID: https://orcid.org/0000-0002-0881-3116, Mazzoni, E.O., Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A.
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Nature Communications 8
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19 September 2017
Touch receptor-derived sensory information alleviates acute pain signaling and fine-tunes nociceptive reflex coordination.
Arcourt, A., Gorham, L., Dhandapani, R., Prato, V., Taberner, F.J., Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095, Gangadharan, V., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Heppenstall, P.A. and Lechner, S.G.
ORCID: https://orcid.org/0000-0001-9402-9127
Neuron 93
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4 January 2017
Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.
Bartus, K., Galino, J., James, N.D., Hernandez-Miranda, L.R.
ORCID: https://orcid.org/0000-0002-0498-708X, Dawes, J.M., Fricker, F.R., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, McMahon, S.B., Ramer, M.S., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Bennett, D.L.H. and Bradbury, E.J.
Brain 139
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May 2016
Bcl11a (Ctip1) controls migration of cortical projection neurons through regulation of Sema3c.
Wiegreffe, C., Simon, R., Peschkes, K., Kling, C., Strehle, M., Cheng, J., Srivatsa, S., Liu, P., Jenkins, N.A., Copeland, N.G., Tarabykin, V. and Britsch, S.
ORCID: https://orcid.org/0000-0003-4379-3322
Neuron 87
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15 July 2015
Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action.
Loos, M., Mueller, T.
ORCID: https://orcid.org/0000-0001-8096-1853, Gouwenberg, Y., Wijnands, R., van der Loo, R.J., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Smit, A.B. and Spijker, S.
Biological Psychiatry 76
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15 October 2014
Human satellite cells have regenerative capacity and are genetically manipulable.
Marg, A.
ORCID: https://orcid.org/0000-0003-3673-4244, Escobar, H.
ORCID: https://orcid.org/0000-0002-8128-7845, Gloy, S., Kufeld, M., Zacher, J., Spuler, A., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Izsvák, Z.
ORCID: https://orcid.org/0000-0002-2053-2384 and Spuler, S.
ORCID: https://orcid.org/0000-0002-0155-1117
Journal of Clinical Investigation 124
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1 October 2014
Parasympathetic neurons originate from nerve-associated peripheral glial progenitors.
Dyachuk, V., Furlan, A., Shahidi, M.K., Giovenco, M., Kaukua, N., Konstantinidou, C., Pachnis, V., Memic, F., Marklund, U., Müller, T.
ORCID: https://orcid.org/0000-0001-8096-1853, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Fried, K., Ernfors, P. and Adameyko, I.
Science 345
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4 July 2014
TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction.
Ragancokova, D., Rocca, E., Oonk, A.M.M., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Rohde, E., Bednarsch, J., Feenstra, I., Pennings, R.J.E., Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095 and Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041
Journal of Clinical Investigation 124
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3 March 2014
Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E.
ORCID: https://orcid.org/0000-0003-3055-0495, McShane, E.
ORCID: https://orcid.org/0000-0002-7806-2063, Cheret, C.
ORCID: https://orcid.org/0000-0001-7382-0403, Walcher, J., Müller, T.
ORCID: https://orcid.org/0000-0001-8096-1853, Wulf-Goldenberg, A., Hoelper, S., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Krüger, M., Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370, Meijer, D., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Lewin, G.R.
ORCID: https://orcid.org/0000-0002-2890-6352, Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751 and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 28
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1 February 2014
BMP signaling controls muscle mass.
Sartori, R., Schirwis, E., Blaauw, B., Bortolanza, S., Zhao, J., Enzo, E., Stantzou, A., Mouisel, E., Toniolo, L., Ferry, A., Stricker, S., Goldberg, A.L., Dupont, S., Piccolo, S., Amthor, H. and Sandri, M.
Nature Genetics 45
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November 2013
Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.
Cheret, C.
ORCID: https://orcid.org/0000-0001-7382-0403, Willem, M., Fricker, F.R., Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095, Wulf-Goldenberg, A., Tahirovic, S., Nave, K.A., Saftig, P., Haass, C., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Bennett, D.L. and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
EMBO Journal 32
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17 July 2013
Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.
Fricker, F.R., Antunes-Martins, A., Galino, J., Paramsothy, R., La Russa, F., Perkins, J., Goldberg, R., Brelstaff, J., Zhu, N., McMahon, S.B., Orengo, C., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Bennett, D.L.
Brain 136
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July 2013
A validated regulatory network for Th17 cell specification.
Ciofani, M., Madar, A., Galan, C., Sellars, M., Mace, K., Pauli, F., Agarwal, A., Huang, W., Parkurst, C.N., Muratet, M., Newberry, K.M., Meadows, S., Greenfield, A., Yang, Y., Jain, P., Kirigin, F.K., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Wagner, E.F., Murphy, K.M., Myers, R.M., Bonneau, R. and Littman, D.R.
Cell 151
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12 October 2012
Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on notch signals.
Broehl, D., Vasyutina, E., Czajkowski, M.T.
ORCID: https://orcid.org/0000-0002-0122-1943, Griger, J.
ORCID: https://orcid.org/0000-0001-8666-3371, Rassek, C., Rahn, H.P.
ORCID: https://orcid.org/0000-0002-5233-3937, Purfürst, B.
ORCID: https://orcid.org/0000-0002-9887-7577, Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095 and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Developmental Cell 23
(3): 469-481.
11 September 2012
The transcription factor c-Maf controls touch receptor development and function.
Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095, Lechner, S.G.
ORCID: https://orcid.org/0000-0001-9402-9127, Cheret, C.
ORCID: https://orcid.org/0000-0001-7382-0403, Bourane, S., Kolanczyk, M.E.
ORCID: https://orcid.org/0000-0003-3055-0495, Pattyn, A., Reuter, K., Munier, F.L., Carroll, P., Lewin, G.R.
ORCID: https://orcid.org/0000-0002-2890-6352 and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Science 335
(6074): 1373-1376.
16 March 2012
Targeting MET in cancer: rationale and progress.
Gherardi, E., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Woude, G.V.
Nature Reviews Cancer 12
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February 2012
Neural crest cell lineage restricts skeletal muscle progenitor cell differentiation through Neuregulin1-ErbB3 signaling.
Van Ho, A.T., Hayashi, S., Broehl, D., Aurade, F., Rattenbach, R. and Relaix, F.
Developmental Cell 21
(2): 273-287.
16 August 2011
A fresh breeze from the ivory tower.
Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Current Opinion in Cell Biology 21
(6): 725-726.
December 2009
Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin.
Adameyko, I., Lallemend, F., Aquino, J.B., Pereira, J.A., Topilko, P., Mueller, T.
ORCID: https://orcid.org/0000-0001-8096-1853, Fritz, N., Beljajeva, A., Mochii, M., Liste, I., Usoskin, D., Suter, U., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Ernfors, P.
Cell 139
(2): 366-379.
16 October 2009
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling.
Trimbuch, T.
ORCID: https://orcid.org/0000-0001-7512-8955, Beed, P., Vogt, J., Schuchmann, S., Maier, N., Kintscher, M., Breustedt, J., Schuelke, M., Streu, N., Kieselmann, O., Brunk, I., Laube, G., Strauss, U., Battefeld, A., Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Wiese, S., Sendtner, M., Kawabe, H., Kishimoto-Suga, M., Brose, N., Baumgart, J., Geist, B., Aoki, J., Savaskan, N.E., Braeuer, A.U., Chun, J., Ninnemann, O., Schmitz, D.
ORCID: https://orcid.org/0000-0003-2741-5241 and Nitsch, R.
Cell 138
(6): 1222-12235.
18 September 2009
c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice.
Giebeler, A., Boekschoten, M.V., Klein, C., Borowiak, M.
ORCID: https://orcid.org/0000-0002-5829-1213, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Gassler, N., Wasmuth, H.E., Mueller, M., Trautwein, C. and Streetz, K.L.
Gastroenterology 137
(1): 297-308.
July 2009
Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of Basal progenitors in the developing mouse neocortex.
Farkas, L.M., Haffner, C., Giger, T., Khaitovich, P., Nowick, K., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Paeaebo, S. and Huttner, W.B.
Neuron 60
(1): 40-55.
9 October 2008
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Brinkmann, B.G., Agarwal, A., Sereda, M.W., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Mueller, T.
ORCID: https://orcid.org/0000-0001-8096-1853, Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095, Stassart, R.M., Nawaz, S., Humml, C., Velanac, V., Radyushkin, K., Goebbels, S., Fischer, T.M., Franklin, R.J., Lai, C., Ehrenreich, H., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Schwab, M.H. and Nave, K.A.
Neuron 59
(4): 581-595.
28 August 2008
A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling.
Hori, K., Cholewa-Waclaw, J.
ORCID: https://orcid.org/0000-0001-8625-8528, Nakada, Y., Glasgow, S.M., Masui, T., Henke, R.M., Wildner, H., Martarelli, B., Beres, T.M., Epstein, J.A., Magnuson, M.A., Macdonald, R.J., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Johnson, J.E.
Genes & Development 22
(2): 166-178.
15 January 2008
Nociceptive tuning by stem cell factor/c-Kit signaling.
Milenkovic, N.
ORCID: https://orcid.org/0000-0002-0014-1140, Frahm, C., Gassmann, M., Griffel, C., Erdmann, B.
ORCID: https://orcid.org/0000-0002-9887-7577, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Lewin, G.R.
ORCID: https://orcid.org/0000-0002-2890-6352 and Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041
Neuron 56
(5): 893-906.
6 December 2007
Notch signaling is essential for ventricular chamber development.
Grego-Bessa, J., Luna-Zurita, L., del Monte, G., Bolos, V., Melgar, P., Arandilla, A., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Zang, H., Mukouyama, Y.S., Chen, H., Shou, W., Ballestar, E., Esteller, M., Rojas, A., Perez-Pomares, J.M. and de la Pompa, J.L.
Developmental Cell 12
(3): 415-429.
March 2007
Control of peripheral nerve myelination by the β-secretase BACE1.
Willem, M., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Novak, B., Citron, M., Kaufmann, S., Rittger, A., Destrooper, B., Saftig, P., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Haass, C.
Science 314
(5799): 664-666.
27 October 2006
The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
Gierl, M.S., Karoulias, N., Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095, Strehle, M. and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 20
(17): 2465-2478.
1 September 2006
Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation.
Lopez-Bendito, G., Cautinat, A., Sanchez, J.A., Bielle, F., Flames, N., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Talmage, D.A., Role, L.W., Charnay, P., Marin, O. and Garel, S.
Cell 125
(1): 127-142.
7 April 2006
CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells.
Vasyutina, E., Stebler, J., Brand-Saberi, B., Schulz, S., Raz, E. and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 19
(18): 2187-2198.
15 September 2005
The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord.
Muller, T.
ORCID: https://orcid.org/0000-0001-8096-1853, Anlag, K., Wildner, H., Britsch, S.
ORCID: https://orcid.org/0000-0003-4379-3322, Treier, M.
ORCID: https://orcid.org/0000-0002-8751-1246 and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 19
(6): 733-743.
1 January 2005
A role for E2F6 in the restriction of male-germ-cell-specific gene expression.
Pohlers, M., Truss, M., Frede, U., Scholz, A., Strehle, M., Kuban, R.J., Hoffmann, B., Morkel, M.
ORCID: https://orcid.org/0000-0002-2553-9999, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Hagemeier, C.
Current Biology 15
(11): 1051-1057.
1 January 2005
Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele.
Graveel, C., Su, Y., Koeman, J., Wang, L.M., Tessarollo, L., Fiscella, M., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Swiatek, P., Bronson, R. and Vande Woude, G.F.
Proceedings of the National Academy of Sciences of the United States of America 101
(49): 17198-17203.
7 December 2004
Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1.
Flames, N., Long, J.E., Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Fischer, T.M., Gassmann, M., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Lai, C., Rubenstein, J.L. and Marin, O.
Neuron 44
(2): 251-261.
14 October 2004
Axonal neuregulin-1 regulates myelin sheath thickness.
Michailov, G.V., Sereda, M.W., Brinkmann, B.G., Fischer, T.M., Haug, B., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Role, L., Lai, C., Schwab, M.H. and Nave, K.A.
Science 304
(5671): 700-703.
30 April 2004
Met provides essential signals for liver regeneration.
Borowiak, M.
ORCID: https://orcid.org/0000-0002-5829-1213, Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041, Wuestefeld, T., Strehle, M., Trautwein, C. and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 101
(29): 10608-10613.
1 January 2004
Met, metastasis, motility and more.
Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4
(12): 915-925.
December 2003
A role for Neuregulin1 signaling in muscle spindle differentiation.
Hippenmeyer, S., Shneider, N.A., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Burden, S.J., Jessell, T.M. and Arber, S.
Neuron 36
(6): 1035-1049.
19 December 2002
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S.
ORCID: https://orcid.org/0000-0003-4379-3322, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Chien, K.R., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041
Proceedings of the National Academy of Sciences of the United States of America 99
(13): 8880-8885.
25 June 2002
Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin.
Mukouyama, Y., Shin, D., Britsch, S.
ORCID: https://orcid.org/0000-0003-4379-3322, Taniguchi, M. and Anderson, D.J.
Cell 109
(6): 693-705.
14 June 2002
The homeodomain factor Lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord.
Müller, T.
ORCID: https://orcid.org/0000-0001-8096-1853, Brohmann, H., Pierani, A., Heppenstall, P.A., Lewin, G.R.
ORCID: https://orcid.org/0000-0002-2890-6352, Jessell, T.M. and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Neuron 34
(4): 551-562.
16 May 2002
Genomics boosts mouse molecular genetics.
Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Treier, M.
ORCID: https://orcid.org/0000-0002-8751-1246
Trends in Genetics 17
(12): 691-692.
1 December 2001
Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
Keilhack, H., Mueller, M., Boehmer, S.A., Frank, C., Weidner, K.M., Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Ligensa, T., Berndt, A., Kosmehl, H., Gunther, B., Mueller, T., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Boehmer, F.D.
Journal of Cell Biology 152
(2): 325-334.
22 January 2001
The transcription factor Sox10 is a key regulator of peripheral glial development.
Britsch, S.
ORCID: https://orcid.org/0000-0003-4379-3322, Goerich, D.E., Riethmacher, D., Peirano, R.I., Rossner, M., Nave, K.A., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Wegner, M.
Genes & Development 15
(1): 66-78.
1 January 2001
Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation.
Yang, X., Arber, S., William, C., Li, L., Tanabe, Y., Jessell, T.M., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Burden, S.J.
Neuron 30
(2): 399-410.
1 January 2001
Genes that control the development of migrating muscle precursor cells.
Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Brohmann, H.
Current Opinion in Cell Biology 12
(6): 725-730.
1 December 2000
Cell differentiation.
Rosenthal, N. and Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872
Current Opinion in Cell Biology 12
: 717-718.
1 December 2000
E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice.
Smits, R., Ruiz, P., Diaz-Cano, S., Luz, A., Jagmohan-Changur, S., Breukel, C., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829 and Fodde, R.
Gastroenterology 119
(4): 1045-1053.
1 October 2000
Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Sachs, M., Brohmann, H., Zechner, D.
ORCID: https://orcid.org/0000-0002-2075-7540, Mueller, T., Huelsken, J., Walther, I., Schaeper, U., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829
Journal of Cell Biology 150
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Blood Cancer Journal 14
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The proteogenomic landscape of multiple myeloma reveals insights into disease biology and therapeutic opportunities.
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Dynamics of clonal hematopoiesis under DNA-damaging treatment in patients with ovarian cancer.
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1 February 2024
Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia.
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Nature Cancer 5
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November 2023
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November 2023
Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert, T., Hsu, C.J., Becker, A.L., Graessle, S.
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October 2023
Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion.
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22 September 2023
Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire.
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September 2023
Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
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ORCID: https://orcid.org/0000-0002-5890-5510, Thol, F., Heuser, M., Paschka, P., Gaidzik, V.I., Saadati, M., Benner, A., Schlenk, R.F., Döhner, K. and Ganser, A.
Lancet Haematology 10
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July 2023
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Lena, A., Wilkenshoff, U., Hadzibegovic, S., Porthun, J., Rösnick, L., Fröhlich, A.K., Zeller, T., Karakas, M., Keller, U.
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Journal of the American College of Cardiology 81
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25 April 2023
Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Straube, J.
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Leukemia 37
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April 2023
Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M.
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Blood 141
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16 February 2023
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.
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Leukemia 37
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February 2023
Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.
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Nature Cancer 4
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January 2023
Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia.
Ling, V.Y.
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Leukemia 37
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January 2023
TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
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Journal for ImmunoTherapy of Cancer 10
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22 December 2022
Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma.
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Cancer Immunology Research 10
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1 November 2022
Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.
Jahn, N., Jahn, E., Saadati, M., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Larson, R.A.
ORCID: https://orcid.org/0000-0001-9168-3203, Ottone, T., Amadori, S., Prior, T.W., Brandwein, J.M., Appelbaum, F.R., Medeiros, B.C.
ORCID: https://orcid.org/0000-0001-6972-8137, Tallman, M.S., Ehninger, G., Heuser, M.
ORCID: https://orcid.org/0000-0001-5318-9044, Ganser, A., Pallaud, C., Gathmann, I., Krzykalla, J., Benner, A., Bloomfield, C.D.
ORCID: https://orcid.org/0000-0001-5465-7591, Thiede, C.
ORCID: https://orcid.org/0000-0003-1241-2048, Stone, R.M.
ORCID: https://orcid.org/0000-0002-7526-2633, Döhner, H. and Döhner, K.
ORCID: https://orcid.org/0000-0002-2261-9862
Leukemia 36
(9): 2218-2227.
September 2022
Precision medicine in myeloid malignancies.
Westermann, J. and Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510
Seminars in Cancer Biology 84
: 153-169.
September 2022
Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.
Zhai, Y., Singh, P., Dolnik, A., Brazda, P., Atlasy, N., Del Gaudio, N., Döhner, K., Döhner, H., Minucci, S., Martens, J., Altucci, L., Megchelenbrink, W., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510 and Stunnenberg, H.G.
Molecular Cancer 21
(1): 166.
19 August 2022
Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi, Y.
ORCID: https://orcid.org/0000-0002-1595-9631, Arango-Ossa, J.E., Zhou, Y., Bernard, E.
ORCID: https://orcid.org/0000-0002-2057-7187, Thomas, I., Gilkes, A., Freeman, S.
ORCID: https://orcid.org/0000-0003-1869-180X, Pradat, Y.
ORCID: https://orcid.org/0000-0002-4647-5779, Johnson, S.J., Hills, R., Dillon, R., Levine, M.F.
ORCID: https://orcid.org/0000-0001-5156-9086, Leongamornlert, D.
ORCID: https://orcid.org/0000-0002-3486-3168, Butler, A., Ganser, A., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, K.
ORCID: https://orcid.org/0000-0002-2261-9862, Ottmann, O., Adams, R.
ORCID: https://orcid.org/0000-0003-3915-7243, Döhner, H.
ORCID: https://orcid.org/0000-0003-2116-5536, Campbell, P.J.
ORCID: https://orcid.org/0000-0002-3921-0510, Burnett, A.K.
ORCID: https://orcid.org/0000-0003-1734-5817, Dennis, M., Russell, N.H., Devlin, S.M.
ORCID: https://orcid.org/0000-0002-6801-720X, Huntly, B.J.P.
ORCID: https://orcid.org/0000-0003-0312-161X and Papaemmanuil, E.
ORCID: https://orcid.org/0000-0003-1709-8983
Nature Communications 13
(1): 4622.
8 August 2022
The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S., Cabantog, A., MacPhee, L., Im, J., Ruess, C., Demir, B., Sperb, N., Rücker, F.G., Döhner, K., Herold, T., Pollack, J.R., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Rouhi, A. and Kuchenbauer, F.
Haematologica 107
(8): 1758-1772.
August 2022
Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow, J., Gross, S., Busack, L., Flörcken, A., Jesse, J., Schwarz, M., Neuendorff, N.R., von Brünneck, A.C., Anagnostopoulos, I., Türkmen, S., Blau, I.W., Burmeister, T., Horst, D., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510 and Westermann, J.
Haematologica 107
(8): 1773-1785.
August 2022
The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells.
Viñado, A.C., Calvo, I.A.
ORCID: https://orcid.org/0000-0001-6619-4571, Cenzano, I.
ORCID: https://orcid.org/0000-0002-9030-3069, Olaverri, D.
ORCID: https://orcid.org/0000-0003-1740-6616, Cocera, M.
ORCID: https://orcid.org/0000-0002-5679-1206, San Martin-Uriz, P., Romero, J.P., Vilas-Zornoza, A., Vera, L., Gomez-Cebrian, N.
ORCID: https://orcid.org/0000-0001-5604-9223, Puchades-Carrasco, L.
ORCID: https://orcid.org/0000-0003-0340-7458, Lisi-Vega, L.E.
ORCID: https://orcid.org/0000-0001-7664-5356, Apaolaza, I.
ORCID: https://orcid.org/0000-0002-8961-4513, Valera, P., Guruceaga, E.
ORCID: https://orcid.org/0000-0003-0547-681X, Granero-Molto, F.
ORCID: https://orcid.org/0000-0003-4817-5232, Ripalda-Cemborain, P.
ORCID: https://orcid.org/0000-0001-8425-3563, Luck, T.J., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Planes, F.J.
ORCID: https://orcid.org/0000-0003-1155-3105, Rifon, J.J., Méndez-Ferrer, S.
ORCID: https://orcid.org/0000-0002-9805-9988, Yusuf, R.Z., Pardo-Saganta, A., Prosper, F.
ORCID: https://orcid.org/0000-0001-6115-8790 and Saez, B.
ORCID: https://orcid.org/0000-0001-7908-7089
Leukemia 36
(8): 1969-1979.
August 2022
Application of precision medicine in clinical routine in haematology - challenges and opportunities.
Wästerlid, T., Cavelier, L., Haferlach, C., Konopleva, M., Fröhling, S., Östling, P., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Fioretos, T. and Smedby, K.E.
Journal of Internal Medicine 292
(2): 243-261.
August 2022
Clonal hematopoiesis of indeterminate potential-related epigenetic age acceleration correlates with clonal hematopoiesis of indeterminate potential clone size in patients with high morbidity.
Feldkamp, J.D., Vetter, V.M., Arends, C.M., Lang, T.J.L., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Damm, F., Demuth, I. and Frick, M.
Haematologica 107
(7): 1703-1708.
July 2022
Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
Schmiester, M., Maier, R., Riedel, R., Durek, P., Frentsch, M., Kolling, S., Mashreghi, M.F., Jenq, R., Zhang, L., Peterson, C.B.
ORCID: https://orcid.org/0000-0003-3316-0468, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Chang, H.D. and Na, I.K.
ORCID: https://orcid.org/0000-0001-9902-5424
Gut Microbes 14
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29 May 2022
The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL.
Rejeski, K.
ORCID: https://orcid.org/0000-0003-3905-0251, Perez, A., Iacoboni, G., Penack, O., Bücklein, V., Jentzsch, L., Mougiakakos, D., Johnson, G., Arciola, B., Carpio, C., Blumenberg, V., Hoster, E., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Locke, F.L., von Bergwelt-Baildon, M., Mackensen, A., Bethge, W., Barba, P., Jain, M.D.
ORCID: https://orcid.org/0000-0002-7789-1257 and Subklewe, M.
Journal for ImmunoTherapy of Cancer 10
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17 May 2022
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca, P., Vonficht, D., Schnell, A., Uckelmann, H.J., Bollhagen, A., Mahmoud, M.A.A., Landua, S.L., van der Salm, E., Trautmann, C., Raffel, S., Grünschläger, F., Lutz, R., Ghosh, M., Renders, S., Correia, N., Donato, E., Dixon, K.O., Hirche, C., Andresen, C., Robens, Cl., Werner, P.S., Boch, T., Eisel, D., Osen, W., Pilz, F., Przybylla, A., Klein, C., Buchholz, F., Milsom, M.D., Essers, M.A.G., Eichmüller, S.B., Hofmann, W.K., Nowak, D., Hübschmann, D., Hundemer, M., Thiede, C., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Müller-Tidow, C., Armstrong, S.A., Trumpp, A., Kuchroo, V.K. and Haas, S.
ORCID: https://orcid.org/0000-0001-9227-2051
Cell Stem Cell 29
(5): 760-775.
5 May 2022
Infectious complications of targeted drugs and biotherapies in acute leukemia. Clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL), a joint venture of the European Group for Blood and Marrow Transplantation (EBMT), the European Organization for Research and Treatment of Cancer (EORTC), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN).
Maschmeyer, G.
ORCID: https://orcid.org/0000-0003-2378-2466, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Garcia-Vidal, C., Herbrecht, R.
ORCID: https://orcid.org/0000-0002-9381-4876, Maertens, J.
ORCID: https://orcid.org/0000-0003-4257-5980, Menna, P., Pagano, L.
ORCID: https://orcid.org/0000-0001-8287-928X, Thiebaut-Bertrand, A. and Calandra, T.
Leukemia 36
(5): 1215-1226.
May 2022
Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F., Hablesreiter, R., Hoyer, K., Hennch, C.
ORCID: https://orcid.org/0000-0003-4104-5531, Maluck-Böttcher, A., Segler, A., Madadi, A., Frick, M., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Briest, F.
ORCID: https://orcid.org/0000-0001-5969-9467 and Damm, F.
ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 36
(4): 1102-1110.
April 2022
Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M., Dimitriou, S., Stahler, A.
ORCID: https://orcid.org/0000-0003-1041-0137, Hablesreiter, R., Strzelecka, P.M.
ORCID: https://orcid.org/0000-0003-0226-6788, Stein, C.M.
ORCID: https://orcid.org/0000-0002-9015-7671, Tilgner, M.
ORCID: https://orcid.org/0000-0003-3196-6214, Saiki, R., Ogawa, S.
ORCID: https://orcid.org/0000-0002-7778-5374, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Modest, D.P., Stintzing, S.
ORCID: https://orcid.org/0000-0002-3297-5801, Heinemann, V. and Damm, F.
Blood 139
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10 March 2022
Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D.
ORCID: https://orcid.org/0000-0001-7959-454X, Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Bohl, S.R., Dolnik, A., Steinebach, C.
ORCID: https://orcid.org/0000-0001-5638-1955, Conrad, T., Müller, S., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Kull, M., Haji, M., Gütschow, M., Döhner, H., Walther, W.
ORCID: https://orcid.org/0000-0003-2884-0231, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Krönke, J.
ORCID: https://orcid.org/0000-0002-4649-0506
Nature Communications 13
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23 February 2022
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M., Schwarzer, A., Jayavelu, A.K., Hsu, C.J., Kirkpatrick, J.
ORCID: https://orcid.org/0000-0001-9291-7294, Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S.A.
ORCID: https://orcid.org/0000-0001-5634-1347, Nafria, M.
ORCID: https://orcid.org/0000-0002-5329-7966, Jiang, L., Dai, Y.T.
ORCID: https://orcid.org/0000-0001-8275-2115, Chen, Z., Chen, S.J., Kellaway, S.G.
ORCID: https://orcid.org/0000-0002-4011-7460, Ptasinska, A., Ng, E.S.
ORCID: https://orcid.org/0000-0002-7970-8129, Stanley, E.G., Elefanty, A.G.
ORCID: https://orcid.org/0000-0001-6448-8314, Buschbeck, M., Bierhoff, H., Brodt, S.
ORCID: https://orcid.org/0000-0003-1286-8766, Matziolis, G., Fischer, K.D., Hochhaus, A., Chen, C.W.
ORCID: https://orcid.org/0000-0002-8737-6830, Heidenreich, O.
ORCID: https://orcid.org/0000-0001-5404-6483, Mann, M., Lane, S.W.
ORCID: https://orcid.org/0000-0002-8050-6209, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Ori, A.
ORCID: https://orcid.org/0000-0002-3046-0871, von Eyss, B.
ORCID: https://orcid.org/0000-0002-4731-6841, Bonifer, C. and Heidel, F.
ORCID: https://orcid.org/0000-0003-2438-1955
Blood 139
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17 February 2022
CEBPA mutations in AML: site matters.
Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510
Blood 139
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6 January 2022
Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
Rücker, F.G., Du, L., Luck, T.J., Benner, A.
ORCID: https://orcid.org/0000-0002-7238-6956, Krzykalla, J., Gathmann, I., Voso, M.T.
ORCID: https://orcid.org/0000-0002-6164-4761, Amadori, S., Prior, T.W., Brandwein, J.M., Appelbaum, F.R., Medeiros, B.C.
ORCID: https://orcid.org/0000-0001-6972-8137, Tallman, M.S., Savoie, L., Sierra, J., Pallaud, C., Sanz, M.A.
ORCID: https://orcid.org/0000-0003-1489-1177, Jansen, J.H., Niederwieser, D.
ORCID: https://orcid.org/0000-0002-4737-1103, Fischer, T., Ehninger, G., Heuser, M.
ORCID: https://orcid.org/0000-0001-5318-9044, Ganser, A., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Larson, R.A.
ORCID: https://orcid.org/0000-0001-9168-3203, Bloomfield, C.D.
ORCID: https://orcid.org/0000-0001-5465-7591, Stone, R.M., Döhner, H., Thiede, C.
ORCID: https://orcid.org/0000-0003-1241-2048 and Döhner, K.
ORCID: https://orcid.org/0000-0002-2261-9862
Leukemia 36
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January 2022
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Bloehdorn, J.
ORCID: https://orcid.org/0000-0003-1433-9702, Braun, A.
ORCID: https://orcid.org/0000-0003-0925-5598, Taylor-Weiner, A., Jebaraj, B.M.C., Robrecht, S., Krzykalla, J., Pan, H., Giza, A., Akylzhanova, G., Holzmann, K., Scheffold, A., Johnston, H.E., Yeh, R.F., Klymenko, T., Tausch, E., Eichhorst, B., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Fischer, K., Weisser, M., Robak, T.
ORCID: https://orcid.org/0000-0002-3411-6357, Schneider, C., Gribben, J.
ORCID: https://orcid.org/0000-0002-8505-7430, Dahal, L.N.
ORCID: https://orcid.org/0000-0001-8390-6593, Carter, M.J., Elemento, O.
ORCID: https://orcid.org/0000-0002-8061-9617, Landau, D.A.
ORCID: https://orcid.org/0000-0003-2346-9541, Neuberg, D.S.
ORCID: https://orcid.org/0000-0003-2566-3145, Cragg, M.S., Benner, A.
ORCID: https://orcid.org/0000-0002-7238-6956, Hallek, M., Wu, C.J.
ORCID: https://orcid.org/0000-0002-3348-5054, Döhner, H., Stilgenbauer, S. and Mertens, D.
Nature Communications 12
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13 September 2021
Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia.
Rapaport, F., Neelamraju, Y., Baslan, T., Hassane, D., Gruszczynska, A.
ORCID: https://orcid.org/0000-0002-7877-8002, de Massy, M.R.
ORCID: https://orcid.org/0000-0002-3048-1680, Farnoud, N., Haddox, S., Lee, T., Medina-Martinez, J., Sheridan, C., Thurmond, A., Becker, M., Bekiranov, S.
ORCID: https://orcid.org/0000-0002-3177-4346, Carroll, M., Moses Murdock, H., Valk, P.J.M., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, D’Andrea, R., Lowe, S.W., Neuberg, D.
ORCID: https://orcid.org/0000-0003-2566-3145, Levine, R.L.
ORCID: https://orcid.org/0000-0002-7884-1905, Melnick, A.
ORCID: https://orcid.org/0000-0002-8074-2287 and Garrett-Bakelman, F.E.
ORCID: https://orcid.org/0000-0002-4771-628X
Leukemia 35
(9): 2688-2692.
September 2021
Genome sequencing in myeloid cancers.
Dolnik, A., Schrezenmeier, J. and Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510
New England Journal of Medicine 384
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24 June 2021
Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Schmalbrock, L.K.
ORCID: https://orcid.org/0000-0002-6080-6175, Dolnik, A., Cocciardi, S., Sträng, E., Theis, F., Jahn, N., Panina, E., Blätte, T.J., Herzig, J.K., Skambraks, S., Rücker, F.G., Gaidzik, V.I., Paschka, P., Fiedler, W., Salih, H.R., Wulf, G.G., Schroeder, T., Lübbert, M., Schlenk, R.F., Thol, F., Heuser, M., Larson, R.A., Ganser, A., Stunnenberg, H.G., Minucci, S., Stone, R.M., Bloomfield, C.D., Döhner, H., Döhner, K. and Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510
Blood 137
(22): 3093-3104.
3 June 2021
A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: results from the CONKO-005 trial.
Hoyer, K., Hablesreiter, R., Inoue, Y., Yoshida, K., Briest, F., Christen, F., Kakiuchi, N., Yoshizato, T., Shiozawa, Y., Shiraishi, Y., Striefler, J.K., Bischoff, S., Lohneis, P., Putter, H., Blau, O., Keilholz, U., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Pelzer, U., Hummel, M., Riess, H., Ogawa, S., Sinn, M. and Damm, F.
EBioMedicine 66
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April 2021
B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased.
Ihlow, J.
ORCID: https://orcid.org/0000-0001-5484-1321, Michaelis, E., Greuel, S., Heynol, V., Lehmann, A., Radbruch, H.
ORCID: https://orcid.org/0000-0001-6941-3397, Meinhardt, J., Miller, F., Herbst, H., Corman, V.M., Westermann, J., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Horst, D., von Brünneck, A.C. and Elezkurtaj, S.
International Journal of Infectious Diseases 103
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February 2021
Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Kapp-Schwoerer, S., Weber, D., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Krönke, J., Theis, F., Rücker, F.G., Teleanu, M.V., Panina, E., Jahn, N., Herzig, J., Kubanek, L., Schrade, A., Göhring, G., Fiedler, W., Kindler, T, Schroeder, T., Mayer, K.T., Lübbert, M., Wattad, M., Götze, K.S.
ORCID: https://orcid.org/0000-0002-6276-8002, Horst, H.A., Koller, E., Wulf, G.
ORCID: https://orcid.org/0000-0002-7669-3785, Schleicher, J., Bentz, M., Krauter, J., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Krzykalla, J., Benner, A.
ORCID: https://orcid.org/0000-0002-7238-6956, Schlenk, R.F.
ORCID: https://orcid.org/0000-0003-2215-2059, Thol, F., Heuser, M., Ganser, A., Döhner, H
ORCID: https://orcid.org/0000-0003-2116-5536 and Döhner, K.
ORCID: https://orcid.org/0000-0002-2261-9862
Blood 136
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24 December 2020
Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Jayavelu, A.K., Schnöder, T.M., Perner, F., Herzog, C., Meiler, A.
ORCID: https://orcid.org/0000-0003-0012-7952, Krishnamoorthy, G.
ORCID: https://orcid.org/0000-0002-7798-6707, Huber, N., Mohr, J., Edelmann-Stephan, B., Austin, R., Brandt, S., Palandri, F.
ORCID: https://orcid.org/0000-0001-8367-5668, Schröder, N., Isermann, B., Edlich, F., Sinha, A.U., Ungelenk, M., Hübner, C.A., Zeiser, R.
ORCID: https://orcid.org/0000-0001-6565-3393, Rahmig, S., Waskow, C.
ORCID: https://orcid.org/0000-0003-3261-0922, Coldham, I.
ORCID: https://orcid.org/0000-0003-4602-6292, Ernst, T., Hochhaus, A., Jilg, S., Jost, P.J.
ORCID: https://orcid.org/0000-0003-2454-0362, Mullally, A., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Mertens, P.R., Lane, S.W.
ORCID: https://orcid.org/0000-0002-8050-6209, Mann, M.
ORCID: https://orcid.org/0000-0003-1292-4799 and Heidel, F.H.
ORCID: https://orcid.org/0000-0003-2438-1955
Nature 588
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3 December 2020
Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells.
Raffel, S.
ORCID: https://orcid.org/0000-0003-4671-1097, Klimmeck, D., Falcone, M.
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17 February 2020
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
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4 December 2019
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Wang, X.
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Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
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Nature Communications 9
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21 March 2018
Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
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Identification of the elementary structural units of the DNA damage response.
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Nature Communications 8
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12 June 2017
Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
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Nature Medicine 22
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Trends in Neurosciences 39
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ORCID: https://orcid.org/0000-0002-5219-5992, Boccaccini, A.R., Scheibel, T. and Engel, F.B.
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ORCID: https://orcid.org/0000-0002-3170-4890, Cheng, J.Y., Russo, G., Hernandez-Miranda, L.R.
ORCID: https://orcid.org/0000-0002-0498-708X, Szymborska, A.
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ORCID: https://orcid.org/0000-0001-9515-7921, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, Haucke, V.
ORCID: https://orcid.org/0000-0003-3119-6993, Gerhardt, H.
ORCID: https://orcid.org/0000-0002-3030-0384, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Kühn, R.
ORCID: https://orcid.org/0000-0003-1694-9803, Krauss, M., Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Pascual, J.M. and Selbach, M.
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Cell 175
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Embryos and embryonic stem cells from the white rhinoceros.
Hildebrandt, T.B., Hermes, R., Colleoni, S., Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Holtze, S., Renfree, M.B.
ORCID: https://orcid.org/0000-0002-4589-0436, Stejskal, J., Hayashi, K., Drukker, M., Loi, P., Göritz, F., Lazzari, G. and Galli, C.
ORCID: https://orcid.org/0000-0002-9529-6136
Nature Communications 9
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4 July 2018
Autologous iPSC-based vaccines elicit anti-tumor responses in vivo.
Kooreman, N.G., Kim, Y., de Almeida, P.E., Termglinchan, V., Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Shao, N.Y., Wei, T.T., Yi, H., Dey, De., Nelakanti, R., Brouwer, T.P., Paik, D.T., Sagiv-Barfi, I., Han, A., Quax, P.H.A., Hamming, J.F., Levy, R., Davis, M.M. and Wu, J.C.
Cell Stem Cell 22
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5 April 2018
A comprehensive TALEN-based knockout library for generating human induced pluripotent stem cell-based models for cardiovascular diseases.
Karakikes, I., Termglinchan, V., Cepeda, D.A., Lee, J., Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Hendel, A., Itzhaki, I., Ameen, M., Shrestha, R., Wu, H., Ma, N., Shao, N.Y., Seeger, T., Woo, N.A., Wilson, K.D., Matsa, E., Porteus, M.H., Sebastiano, V. and Wu, J.C.
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Dieterich, Christoph (BIMSB)
MOV10 is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.
Gregersen, L.H.
ORCID: https://orcid.org/0000-0002-1205-604X, Schueler, M., Munschauer, M.
ORCID: https://orcid.org/0000-0001-6143-4548, Mastrobuoni, G.
ORCID: https://orcid.org/0000-0003-4509-1295, Chen, W.
ORCID: https://orcid.org/0000-0003-3263-1627, Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299, Dieterich, C.
ORCID: https://orcid.org/0000-0001-9468-6311 and Landthaler, M.
ORCID: https://orcid.org/0000-0002-1075-8734
Molecular Cell 54
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22 May 2014
Differential protein occupancy profiling of the mRNA transcriptome.
Schueler, M., Munschauer, M.
ORCID: https://orcid.org/0000-0001-6143-4548, Gregersen, L.H.
ORCID: https://orcid.org/0000-0002-1205-604X, Finzel, A., Loewer, A., Chen, W.
ORCID: https://orcid.org/0000-0003-3263-1627, Landthaler, M.
ORCID: https://orcid.org/0000-0002-1075-8734 and Dieterich, C.
ORCID: https://orcid.org/0000-0001-9468-6311
Genome Biology 15
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13 January 2014
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz, A.G., Munschauer, M.
ORCID: https://orcid.org/0000-0001-6143-4548, Schwanhaeusser, B., Vasile, A.
ORCID: https://orcid.org/0000-0001-5452-9960, Murakawa, Y., Schueler, M., Youngs, N., Penfold-Brown, D., Drew, K., Milek, M.
ORCID: https://orcid.org/0000-0002-0803-8439, Wyler, E.
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ORCID: https://orcid.org/0000-0003-2454-8751, Dieterich, C.
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ORCID: https://orcid.org/0000-0002-1075-8734
Molecular Cell 46
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8 June 2012
De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics.
Adamidi, C., Wang, Y., Gruen, D., Mastrobuoni, G.
ORCID: https://orcid.org/0000-0003-4509-1295, You, X., Tolle, D.
ORCID: https://orcid.org/0000-0001-5082-2377, Dodt, M., Mackowiak, S.D., Gogol-Doering, A.
ORCID: https://orcid.org/0009-0001-7697-0551, Oenal, P., Rybak, A.
ORCID: https://orcid.org/0000-0002-1192-5290, Ross, E., Alvarado, A.S., Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299, Dieterich, C.
ORCID: https://orcid.org/0000-0001-9468-6311, Rajewsky, N.
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Genome Research 21
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July 2011
Proteogenomics of Pristionchus pacificus reveals distinct proteome structure of nematode models.
Borchert, N., Dieterich, C.
ORCID: https://orcid.org/0000-0001-9468-6311, Krug, K., Schuetz, W., Jung, S., Nordheim, A., Sommer, R.J. and Macek, B.
Genome Research 20
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June 2010
Dietz, Rainer
ARC is a novel therapeutic approach against acetaminophen-induced hepatocellular necrosis.
An, J., Mehrhof, F., Harms, C., Lättig-Tünnemann, G.
ORCID: https://orcid.org/0000-0001-6485-1136, Lee, S.L.L., Endres, M., Li, M., Sellge, G., Mandic, A.D., Trautwein, C. and Donath, S.
Journal of Hepatology 58
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February 2013
TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure.
An, J., Harms, C., Lättig-Tünnemann, G.
ORCID: https://orcid.org/0000-0001-6485-1136, Sellge, G., Mandic, A.D., Malato, Y., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Endres, M., Trautwein, C. and Donath, S.
Hepatology 56
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August 2012
Guidelines for the use and interpretation of assays for monitoring autophagy.
Klionsky, D.J., Abdalla, F.C., Abeliovich, H., Abraham, R.T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Milojkovic, A. and Simon, A.K.
ORCID: https://orcid.org/0000-0002-4077-7995
Autophagy 8
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April 2012
Effect of binge drinking on the heart as assessed by cardiac magnetic resonance imaging.
Zagrosek, A., Messroghli, D., Schulz, O., Dietz, R. and Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092
JAMA: Journal of the American Medical Association 304
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22 September 2010
Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon: their potential impact for early risk assessment in asymptomatic Chagas' patients.
Munoz Saravia, S.G., Haberland, A., Bartel, S., Araujo, R., Valda, G., Duchen, D., Diaz Ramirez, I., Borges, A.C., Wallukat, G. and Schimke, I.
Journal of the American College of Cardiology 56
(6): 526-527.
3 August 2010
Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon their potential impact for early risk assessment in asymptomatic Chagas' patients.
Wallukat, G., Munoz Saravia, S.G., Haberland, A., Bartel, S., Araujo, R., Valda, G., Duchen, D., Diaz Ramirez, I., Borges, A.C. and Schimke, I.
Journal of the American College of Cardiology 55
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2 February 2010
Noninvasive detection of fibrosis applying contrast-enhanced cardiac magnetic resonance in different forms of left ventricular hypertrophy relation to remodeling.
Rudolph, A., Abdel-Aty, H., Bohl, S., Boye, P., Zagrosek, A., Dietz, R. and Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092
Journal of the American College of Cardiology 53
(3): 284-291.
20 January 2009
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
Monti, J., Fischer, J.
ORCID: https://orcid.org/0000-0003-0398-7720, Paskas, S.
ORCID: https://orcid.org/0000-0002-1206-5376, Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Goesele, C., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Fischer, R.
ORCID: https://orcid.org/0000-0002-4828-2882, Schmidt, C., Schirdewan, A., Gross, V., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Maatz, H.
ORCID: https://orcid.org/0000-0002-9232-6272, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Vingron, M., Weldon, S.M., Lindpaintner, K., Hammock, B.D., Rohde, K., Dietz, R., Cook, S.A., Schunck, W.H.
ORCID: https://orcid.org/0000-0001-7965-7731, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Genetics 40
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May 2008
The salvaged area at risk in reperfused acute myocardial infarction as visualized by cardiovascular magnetic resonance.
Friedrich, M.G., Abdel-Aty, H., Taylor, A.J., Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Messroghli, D. and Dietz, R.
Journal of the American College of Cardiology 51
(16): 1581-1587.
22 April 2008
Subacute coronary stent thrombosis in cancer patients.
Gross, C.M., Posch, M.G., Geier, C.
ORCID: https://orcid.org/0000-0001-5281-8187, Olthoff, H., Kraemer, J., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Dietz, R. and Oezcelik, C.
Journal of the American College of Cardiology 51
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25 March 2008
Protein kinase CK2 links extracellular growth factor signaling with the control of p27(Kip1) stability in the heart.
Hauck, L., Harms, C., An, J., Rohne, J., Gertz, K., Endres, M., Dietz, R. and von Harsdorf, R.
Nature Medicine 14
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March 2008
Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress.
Donath, S., Li, P., Willenbockel, C., Al-Saadi, N., Gross, V., Willnow, T.E.
ORCID: https://orcid.org/0000-0001-9515-7921, Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164, Martin, U., Bauersachs, J., Wollert, K.C., Dietz, R. and von Harsdorf, R.
Circulation 113
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7 March 2006
Letter regarding article by Sharkey et al. "Acute and reversible cardiomyopathy provoked by stress in women from the United States".
Abdel-Aty, H., Dietz, R. and Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092
Circulation 112
: e51.
19 July 2005
Urokinase-induced signaling in human vascular smooth muscle cells is mediated by PDGFR-beta.
Kiyan, J., Kiyan, R., Haller, H. and Dumler, I.
EMBO Journal 24
(10): 1787-1797.
18 May 2005
Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo.
Freund, C., Schmidt-Ullrich, R.
ORCID: https://orcid.org/0000-0002-2472-6530, Baurand, A., Dunger, S., Schneider, W., Loser, P., El-Jamali, A., Dietz, R., Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129 and Bergmann, M.W.
Circulation 111
(18): 2319-2325.
1 January 2005
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Wichter, T., Paul, M., Basson, C.T., McDermott, D.A., Lerman, B.B., Markowitz, S.M., Ellinor, P.T., MacRae, C.A., Peters, S., Grossmann, K.S., Drenckhahn, J.
ORCID: https://orcid.org/0000-0001-8347-7696, Michely, B., Sasse-Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Dietz, R., Breithardt, G., Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36
(11): 1162-1164.
November 2004
Delayed enhancement and T2-weighted cardiovascular magnetic resonance imaging differentiate acute from chronic myocardial infarction.
Abdel-Aty, H., Zagrosek, A., Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Taylor, A.J., Messroghli, D., Kumar, A., Gross, M., Dietz, R. and Friedrich, M.G.
Circulation 109
(20): 2411-2416.
25 May 2004
Mortality and morbidity reduction with candesartan in patients with chronic heart failure and left ventricular systolic dysfunction. Results of the CHARM low-left ventricular ejection fraction trials.
Young, J.B., Dunlap, M.E., Pfeffer, M.A., Probstfield, J.L., Cohen-Solal, A., Dietz, R., Granger, C.B., Hradec, J., Kuch, J., McKelvie, R.S., McMurray, J.J.V., Michelson, E.L., Olofsson, B., Ostergren, J., Held, P., Solomon, S.D., Yusuf, S. and Swedberg, K.
Circulation 110
(17): 2618-2626.
1 January 2004
Regenerative capacity of the myocardium: implications for treatment of heart failure.
von Harsdorf, R., Poole-Wilson, P.A. and Dietz, R.
Lancet 363
: 1306-1313.
1 January 2004
Hydroxymethylglutaryl coenzyme A reductase inhibition reduces Chlamydia pneumoniae-induced cell interaction and activation.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Gieffers, J., Dietz, R., Joerres, A., Rupp, J., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Maass, M.
Circulation 108
(3): 261-265.
22 July 2003
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Viedt, C., Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Ugele, B., Brandes, R.P., Wallukat, G., Park, J.K., Janke, J.
ORCID: https://orcid.org/0000-0003-0113-4118, Barta, P., Theuer, J., Fiebeler, A., Homuth, V., Dietz, R., Haller, H., Kreuzer, J. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 107
(12): 1632-1639.
1 April 2003
Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy.
Geier, C.
ORCID: https://orcid.org/0000-0001-5281-8187, Perrot, A.
ORCID: https://orcid.org/0000-0002-8800-342X, Ozcelik, C., Binner, P., Counsell, D., Hoffmann, K., Pilz, B., Martiniak, Y., Gehmlich, K.
ORCID: https://orcid.org/0000-0003-4019-1844, van der Ven, P.F.M., Furst, D.O., Vornwald, A., von Hodenberg, E., Nuernberg, P., Scheffold, T., Dietz, R. and Osterziel, K.J.
Circulation 107
(10): 1390-1395.
18 March 2003
Blood oxygen level-dependent magnetic resonance imaging in patients with stress-induced angina.
Friedrich, M.G., Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Gross, C.M. and Dietz, R.
Circulation 108
(18): 2219-2223.
1 January 2003
Management of heart failure in primary care (the IMPROVEMENT of Heart Failure Programme): an international survey.
Cleland, J.G.F., Cohen-Solal, A., Aguilar, J.C., Dietz, R., Eastaugh, J., Follath, F., Freemantle, N., Gavazzi, A., van Gilst, W.H., Hobbs, F.D.R., Korewicki, J., Madeira, H.C., Preda, I., Swedberg, K. and Widimsky, J.
Lancet 360
(9346): 1631-1639.
23 November 2002
Hemodynamic and neurohumoral effects of selective endothelin A (ET(A))receptor blockade in chronic heart failure: the Heart Failure ET(A) Receptor Blockade trial (HEAT).
Luescher, T.F., Enseleit, F., Pacher, R., Mitrovic, V., Schulze, M.R., Willenbrock, R., Dietz, R., Rousson, V., Huerlimann, D., Philipp, S., Notter, T., Noll, G. and Ruschitzka, F.
Circulation 106
(21): 2666-2672.
19 November 2002
Phosphorylation by protein kinase CK2: A signaling switch for the caspase-inhibiting protein ARC.
Li, P.F., Li, J.C., Mueller, E.C., Otto, A., Dietz, R. and von Harsdorf, R.
Molecular Cell 10
(2): 247-258.
August 2002
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S.
ORCID: https://orcid.org/0000-0003-4379-3322, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Chien, K.R., Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041
Proceedings of the National Academy of Sciences of the United States of America 99
(13): 8880-8885.
25 June 2002
Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure - Results from 2 placebo-controlled studies.
Doehner, W., Schoene, N., Rauchhaus, M., Leyva-Leon, F., Pavitt, D.V., Reaveley, D.A., Schuler, G., Coats, A.J.S., Anker, S.D. and Hambrecht, R.
Circulation 105
(22): 2619-2624.
4 June 2002
Calcineurin in human heart hypertrophy.
Ritter, O., Hack, S., Schuh, K., Roethlein, N., Perrot, A.
ORCID: https://orcid.org/0000-0002-8800-342X, Osterziel, K.J., Schulte, H.D. and Neyses, L.
Circulation 105
(19): 2265-2269.
14 May 2002
Assessment of survival in patients with primary pulmonary hypertension importance of cardiopulmonary exercise testing.
Wensel, R., Opitz, C.F., Anker, S.D., Winkler, J., Hoffken, G., Kleber, F.X., Sharma, R., Hummel, M., Hetzer, R. and Ewert, R.
Circulation 106
(3): 319-324.
1 January 2002
MRI versus 3D echocardiography in postinterventional patients with hypertrophic obstructive cardiomyopathy - Response.
Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Strohm, O., Waigand, J., Uhlich, F., Dietz, R. and Friedrich, M.G.
Circulation 104
: E32-E33.
14 August 2001
Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Fiebeler, A., Park, J.K., Muller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Theuer, J., Mervaala, E., Bieringer, M., Gulba, D., Dietz, R., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Haller, H.
Circulation 104
: 576-581.
1 January 2001
In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
Mehrhof, F.B., Mueller, F.U., Bergmann, M.W., Li, P.F., Wang, Y.B., Schmitz, W., Dietz, R. and von Harsdorf, R.
Circulation 104
: 2088-2094.
1 January 2001
Enhanced ventilatory response to exercise in patients with chronic heart failure and preserved exercise tolerance - Marker of abnormal cardiorespiratory reflex control and predictor of poor prognosis.
Ponikowski, P., Francis, D.P., Piepoli, M.F., Davies, L.C., Chua, T.P., Davos, C.H., Florea, V., Banasiak, W., Poole-Wilson, P.A., Coats, A.J.S. and Anker, S.D.
Circulation 103
: 967-972.
1 January 2001
Peripheral chemoreceptor hypersensitivity - An ominous sign in patients with chronic heart failure.
Ponikowski, P., Chua, T.P., Anker, S.D., Francis, D.P., Doehner, W., Banasiak, W., Poole-Wilson, P.A., Piepoli, M.F. and Coats, A.J.S.
Circulation 104
(5): 544-549.
1 January 2001
Plasma Cytokine Parameters and Mortality in Patients with Chronic Heart Failure.
Rauchhaus, M., Doehner, W., Francis, D.P., Davos, C., Kemp, M., Liebenthal, C., Niebauer, J., Hooper, J., Volk, H.D., Coats, A.J.S. and Anker, S.D.
Circulation 102
(25): 3060-3067.
19 December 2000
Severe mitral regurgitation after valve replacement as cause of pulmonary venous aneurysm.
Christow, S.P. and Dietz, R.
Circulation 102
(17): 2159-2160.
24 October 2000
The endotoxin-lipoprotein hypothesis.
Rauchhaus, M., Coats, A.J.S. and Anker, S.D.
Lancet 356
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9 September 2000
AT1 receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Homuth, V., Wallukat, G., Kreuzer, J., Park, J.K., Theuer, J., Juepner, A., Gulba, D.C., Mackman, N., Haller, H. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 101
: 2382-2387.
23 May 2000
The value of magnetic resonance imaging of the left ventricular outflow tract in patients with hypertrophic obstructive cardiomyopathy after septal artery embolization.
Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Strohm, O., Waigand, J., Uhlich, F., Dietz, R. and Friedrich, M.G.
Circulation 101
: 1764-1766.
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ORCID: https://orcid.org/0000-0001-7991-3643, Chu, Y.W., Chen, A.I., Lebovic, D., Salles, G.A., Czuczman, M.S., Palanca-Wessels, M.C., Press, O.W., Advani, R., Morschhauser, F., Cheson, B.D., Lenz, P., Ott, G., Polson, A.G., Mundt, K.E. and Lenz, G.
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Journal of Clinical Oncology 33
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ORCID: https://orcid.org/0000-0002-5548-2022, Lenze, D., Hummel, M., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Doerken, B.
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ORCID: https://orcid.org/0009-0000-0257-4049, Fichtner, I., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Dirnhofer, S., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Janz, M.
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1 January 2015
Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
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ORCID: https://orcid.org/0000-0002-0253-081X, Mensen, A., Gloger, M., Heinig, K., Lamprecht, B., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Bégay, V.
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Nature Communications 5
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Journal of Clinical Oncology 32
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10 August 2014
Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma.
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Nature Medicine 20
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Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
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ORCID: https://orcid.org/0000-0002-3114-7975, von Kries, J.P.
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ORCID: https://orcid.org/0000-0001-7991-3643, Lenz, P., Lenz, G., Schendel, D.J. and Krappmann, D.
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The sorting receptor sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells.
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The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P.
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ORCID: https://orcid.org/0000-0002-5548-2022, Sleckman, B.P., de Alboran, I.M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Rodig, S. and Rajewsky, K.
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ORCID: https://orcid.org/0000-0001-7991-3643, Engel, N., Topp, M., Klutmann, S., Amthauer, H., Bockisch, A., Kluge, R., Kratochwil, C., Schober, O., Greil, R., Andreesen, R., Kneba, M., Pfreundschuh, M., Stein, H., Eich, H.T., Mueller, R.P., Dietlein, M., Borchmann, P. and Diehl, V.
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Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells.
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April 2012
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Terwey, T.H., Vega-Ruiz, A., Hemmati, P.G., Martus, P., Dietz, E., le Coutre, P., Massenkeil, G., Doerken, B.
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March 2012
Eight cycles of escalated-dose BEACOPP compared with four cycles of escalated-dose BEACOPP followed by four cycles of baseline-dose BEACOPP with or without radiotherapy in patients with advanced-stage Hodgkin's lymphoma: final analysis of the HD12 trial of the German Hodgkin study group.
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10 November 2011
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15 October 2011
Severe peripheral arterial disease during nilotinib therapy.
Le Coutre, P., Rea, D., Abruzzese, E., Dombret, H., Trawinska, M.M., Herndlhofer, S., Doerken, B.
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7 September 2011
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
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1 August 2011
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10 May 2011
Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial.
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ORCID: https://orcid.org/0000-0001-7991-3643, Rank, A., Grosu, A.L., Wiegel, T., Karstens, J.H., Greil, R., Willich, N., Schmidberger, H., Doehner, H., Borchmann, P., Mueller-Hermelink, H.K., Mueller, R.P. and Engert, A.
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20 September 2010
Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.
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12 August 2010
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
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Nature Medicine 16
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Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence.
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C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
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1 January 2010
The dangers of transcription.
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Cell 139
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11 December 2009
C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
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Escalated-dose BEACOPP in the treatment of patients with advanced-stage Hodgkin's lymphoma: 10 years of follow-up of the GHSG HD9 study.
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The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.
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CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
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Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial.
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Sun, M.L., Yao, W., Wang, X.Y., Gao, S., Varady, K.A., Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Zhang, M., Shi, Z.Y., Cao, F., Zou, B.J., Sun, M.H., Liu, K.X., Bao, Q., Xu, J., Qin, X., Xiao, Q., Wu, L., Zhao, Y.H., Zhang, D.Y., Wu, Q.J. and Gong, T.T
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April 2024
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Dörner, P.J., Anandakumar, H.
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ORCID: https://orcid.org/0000-0001-8365-2546, Fiocca Vernengo, F.
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Nature Communications 14
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20 September 2023
The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis.
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Nature Communications 14
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1 September 2023
Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
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Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G.
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The effect of probiotic and synbiotic supplementation on lipid parameters among patients with cardiometabolic risk factors: a systematic review and meta-analysis of clinical trials.
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Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
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Tracking transient conformational states of T4 lysozyme at room temperature combining X-ray crystallography and site-directed spin labeling.
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Journal of the American Chemical Society 138
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Bacteriophage tailspikes and bacterial O-antigens as a model system to study weak-affinity protein-polysaccharide interactions.
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ORCID: https://orcid.org/0000-0001-7427-6681, Held, M., Roske, Y.
ORCID: https://orcid.org/0000-0001-6237-388X, Schulze, D., Haucke, V., Noe, F. and Daumke, O.
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ORCID: https://orcid.org/0000-0002-0606-2574, Heinemann, U.
ORCID: https://orcid.org/0000-0002-8191-3850, Sommer, T.
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Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.
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Crystal structure of CspA, the major cold shock protein of Escherichia coli.
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Hellmann-Regen, Julian (ECRC)
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ORCID: https://orcid.org/0009-0005-3812-023X, Wagner, Michael, Kuhn, Elizabeth, Roeske, Sandra, Amthauer, Holger, Bartels, Claudia, Boecker, Henning, Brosseron, Frederic, Buchert, Ralph, Buerger, Katharina, Daamen, Marcel, Drzezga, Alexander, Düzel, Emrah, Ersözlü, Ersin, Essler, Markus, Ewers, Michael, Fliessbach, Klaus, Glanz, Wenzel, Hellmann-Regen, Julian
ORCID: https://orcid.org/0000-0003-0411-9204, Incesoy, Enise I., Janowitz, Daniel, Kafali, Konstantinia, Kilimann, Ingo, Krause, Bernd Joachim, Kronmüller, Marie, Laske, Christoph, Maier, Franziska, Maurer, Angelika, Michely, Jochen, Perneczky, Robert, Peters, Oliver
ORCID: https://orcid.org/0000-0003-0568-2998, Preis, Lukas
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Nature Communications 17
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ORCID: https://orcid.org/0000-0002-3284-0632, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kirwan, J.A.
ORCID: https://orcid.org/0000-0002-5423-1651, Berndt, N., MacRae, C.A., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912
Cardiovascular Research 119
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December 2023
Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A.
ORCID: https://orcid.org/0000-0002-1263-2078, Walter, S., Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, McMurray, B.J., Sunaga-Franze, D.Y.
ORCID: https://orcid.org/0000-0002-6851-9162, Xu, M., Zühlke, K., Russwurm, M., Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Langanki, R., Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Patzak, A., Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Borodina, T.
ORCID: https://orcid.org/0000-0002-6978-016X, Persson, P.B., Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164 and Klussmann, E.
ORCID: https://orcid.org/0000-0003-4004-5003
Kidney International 104
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August 2023
A consensus protocol for functional connectivity analysis in the rat brain.
Grandjean, J., Desrosiers-Gregoire, G., Anckaerts, C., Angeles-Valdez, D., Ayad, F., Barrière, D.A., Blockx, I., Bortel, A., Broadwater, M., Cardoso, B.M., Célestine, M., Chavez-Negrete, J.E., Choi, S., Christiaen, E., Clavijo, P., Colon-Perez, L., Cramer, S., Daniele, T., Dempsey, E., Diao, Y., Doelemeyer, A., Dopfel, D., Dvořáková, L., Falfán-Melgoza, C., Fernandes, F.F., Fowler, C.F., Fuentes-Ibañez, A., Garin, C.M., Gelderman, E., Golden, C.E.M., Guo, C.C G., Henckens, M.J.A.G., Hennessy, L.A., Herman, P., Hofwijks, N., Horien, C., Ionescu, T.M., Jones, J., Kaesser, J., Kim, E., Lambers, H., Lazari, A., Lee, S.H., Lillywhite, A., Liu, Y., Liu, Y.Y., López-Castro, A., López-Gil, X., Ma, Z., MacNicol, E., Madularu, D., Mandino, F., Marciano, S., McAuslan, M.J., McCunn, P., McIntosh, A., Meng, X., Meyer-Baese, L., Missault, S., Moro, F., Naessens, D.M.P., Nava-Gomez, L.J., Nonaka, H., Ortiz, J.J., Paasonen, J., Peeters, L.M., Pereira, M., Perez, P.D., Pompilus, M., Prior, M., Rakhmatullin, R., Reimann, H.M.
ORCID: https://orcid.org/0000-0003-1053-9256, Reinwald, J., Del Rio, R.T., Rivera-Olvera, A., Ruiz-Pérez, D., Russo, G., Rutten, T.J., Ryoke, R., Sack, M., Salvan, P., Sanganahalli, B.G., Schroeter, A., Seewoo, B.J., Selingue, E., Seuwen, A., Shi, B., Sirmpilatze, N., Smith, J.A.B., Smith, C., Sobczak, F., Stenroos, P.J., Straathof, M., Strobelt, S., Sumiyoshi, A., Takahashi, K., Torres-García, M.E, Tudela, R., van den Berg, M., van der Marel, K., van Hout, A.T.B., Vertullo, R., Vidal, B., Vrooman, R.M., Wang, V.X., Wank, I., Watson, D.J.G., Yin, T., Zhang, Y., Zurbruegg, S., Achard, S., Alcauter, S., Auer, D.P., Barbier, E.L., Baudewig, J., Beckmann, C.F., Beckmann, N., Becq, G.J.P.C., Blezer, E.L.A., Bolbos, R., Boretius, S., Bouvard, S., Budinger, E., Buxbaum, J.D., Cash, D., Chapman, V., Chuang, K.H., Ciobanu, L., Coolen, B.F., Dalley, J.W., Dhenain, M., Dijkhuizen, R.M., Esteban, O., Faber, C., Febo, M., Feindel, K.W., Forloni, G., Fouquet, J., Garza-Villarreal, E.A., Gass, N., Glennon, J.C., Gozzi, A., Gröhn, O., Harkin, A., Heerschap, A., Helluy, X., Herfert, K., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Homberg, J.R., Houwing, D.J., Hyder, F., Ielacqua, G.D.
ORCID: https://orcid.org/0000-0002-0816-6617, Jelescu, I.O., Johansen-Berg, H., Kaneko, G., Kawashima, R., Keilholz, S.D., Keliris, G.A., Kelly, C., Kerskens, C., Khokhar, J.Y., Kind, P.C., Langlois, J.B., Lerch, J.P., López-Hidalgo, M.A, Manahan-Vaughan, D., Marchand, F., Mars, R.B., Marsella, G., Micotti, E., Muñoz-Moreno, E., Near, J., Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Otte, W.M., Pais-Roldán, P., Pan, W.J., Prado-Alcalá, R.A., Quirarte, G.L., Rodger, J., Rosenow, T., Sampaio-Baptista, C., Sartorius, A., Sawiak, S.J., Scheenen, T.W.J., Shemesh, N., Shih, Y.Y.I., Shmuel, A., Soria, G., Stoop, R., Thompson, G.J., Till, S.M., Todd, N., Van Der Linden, A., van der Toorn, A., van Tilborg, G.A.F, Vanhove, C., Veltien, A., Verhoye, M., Wachsmuth, L., Weber-Fahr, W., Wenk, P., Yu, X., Zerbi, V., Zhang, N., Zhang, B.B., Zimmer, L., Devenyi, G.A., Chakravarty, M.M. and Hess, A.
Nature Neuroscience 26
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April 2023
Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M., Mücke, M.B.
ORCID: https://orcid.org/0000-0002-4957-3307, Pallien, T., Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Sholokh, A.
ORCID: https://orcid.org/0000-0002-1263-2078, Schächterle, C., Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Kidd, A., Walter, S.
ORCID: https://orcid.org/0000-0002-2041-2921, Esmati, Y.
ORCID: https://orcid.org/0000-0001-9010-8119, McMurray, B.J.
ORCID: https://orcid.org/0000-0003-3394-0667, Lato, D.F.
ORCID: https://orcid.org/0000-0002-9263-8532, Sunaga-Franze, D.Y.
ORCID: https://orcid.org/0000-0002-6851-9162, Dierks, P.H.
ORCID: https://orcid.org/0000-0001-5903-8343, Flores, B.I.M., Walker-Gray, R., Gong, M.
ORCID: https://orcid.org/0000-0001-7384-3429, Merticariu, C., Zühlke, K., Russwurm, M., Liu, T., Batolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Pautz, S., Schelenz, S., Taube, M., Napieczynska, H.
ORCID: https://orcid.org/0000-0001-5091-1185, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Eichhorst, J., Lehmann, M., Miller, D.C.
ORCID: https://orcid.org/0000-0001-9852-677X, Diecke, S.
ORCID: https://orcid.org/0000-0002-5219-5992, Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Popova, E.
ORCID: https://orcid.org/0000-0002-3043-9650, Langanki, R., Movsesian, M.A., Herberg, F.W.
ORCID: https://orcid.org/0000-0001-7117-7653, Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Borodina, T.
ORCID: https://orcid.org/0000-0002-6978-016X, Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164 and Klussmann, E.
ORCID: https://orcid.org/0000-0003-4004-5003
Circulation 146
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6 December 2022
Selective endocytosis of Ca(2+)-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.
Azarnia Tehran, D.
ORCID: https://orcid.org/0000-0001-8955-7240, Kochlamazashvili, G., Pampaloni, N. P.
ORCID: https://orcid.org/0000-0002-4066-0295, Sposini, S.
ORCID: https://orcid.org/0000-0001-7681-8376, Shergill, J.K.
ORCID: https://orcid.org/0000-0001-5506-2995, Lehmann, M.
ORCID: https://orcid.org/0000-0002-8370-6353, Pashkova, N.
ORCID: https://orcid.org/0000-0002-2191-4683, Schmidt, C., Löwe, D., Napieczynska, H., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Plested, A.J.R.
ORCID: https://orcid.org/0000-0001-6062-0832, Perrais, D.
ORCID: https://orcid.org/0000-0002-5878-5408, Piper, R.C.
ORCID: https://orcid.org/0000-0001-9995-5699, Haucke, V.
ORCID: https://orcid.org/0000-0003-3119-6993 and Maritzen, T.
ORCID: https://orcid.org/0000-0001-9995-5699
Science Advances 8
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27 May 2022
Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M.
ORCID: https://orcid.org/0000-0001-7132-8079, Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M.
ORCID: https://orcid.org/0000-0002-9373-4753, Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Butter, C., Felix, S.B., Otto, O., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Slevogt, H. and Fielitz, J.
ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 12
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December 2021
Age-related decline in murine heart and skeletal muscle performance is attenuated by reduced Ahnak1 expression.
Mahmoodzadeh, S.
ORCID: https://orcid.org/0000-0002-3094-7874, Koch, K., Schriever, C., Xu, J.
ORCID: https://orcid.org/0000-0001-8552-4134, Steinecker, M., Leber, J., Dworatzek, E., Purfürst, B.
ORCID: https://orcid.org/0000-0002-9887-7577, Kunz, S.
ORCID: https://orcid.org/0000-0002-0131-3506, Recchia, D., Canepari, M., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Di Francescantonio, S.
ORCID: https://orcid.org/0000-0002-4815-491X and Morano, I.
ORCID: https://orcid.org/0000-0001-7315-2222
Journal of Cachexia Sarcopenia and Muscle 12
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14 October 2021
Mitigated viral myocarditis in A/J mice by the immunoproteasome inhibitor ONX 0914 depends on inhibition of systemic inflammatory responses in CoxsackievirusB3 infection.
Goetzke, C.C., Althof, N., Neumaier, H.L., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Kaya, Z., Kespohl, M., Klingel, K. and Beling, A.
ORCID: https://orcid.org/0000-0002-1826-5248
Basic Research in Cardiology 116
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1 February 2021
Phosphodiesterase 3A and arterial hypertension.
Ercu, M., Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Schächterle, C., Tsvetkov, D.
ORCID: https://orcid.org/0000-0002-6472-971X, Cui, Y., Maghsodi, S., Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Zühlke, K., Gregersen, N., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Hodge, R., Mühl, A., Pohl, B., Molé-Illas, R., Geelhaar, A., Walter, S., Napieczynska, H.
ORCID: https://orcid.org/0000-0001-5091-1185, Schelenz, S., Taube, M., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Anistan, Y.M., Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Todiras, M.
ORCID: https://orcid.org/0000-0002-9373-4753, Plehm, R., Popova, E.
ORCID: https://orcid.org/0000-0002-3043-9650, Langanki, R., Eichhorst, J., Lehmann, M., Wiesner, B., Russwurm, M., Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Kamer, I., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Gollasch, M.
ORCID: https://orcid.org/0000-0003-2797-1934, Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Klussmann, E.
ORCID: https://orcid.org/0000-0003-4004-5003
Circulation 142
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14 July 2020
Heart-specific immune responses in an animal model of autoimmune-related myocarditis mitigated by an immunoproteasome inhibitor and genetic ablation.
Bockstahler, M., Fischer, A., Goetzke, C.C., Neumaier, H.L., Sauter, M., Kespohl, M., Müller, A.M., Meckes, C., Salbach, C., Schenk, M., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Landmesser, U., Weiner, J.
ORCID: https://orcid.org/0000-0003-1438-7819, Meder, B., Lehmann, L., Kratzer, A., Klingel, K., Katus, H.A., Kaya, Z. and Beling, A.
Circulation 141
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9 June 2020
RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738, Foster, D.J., Cunningham, M.W., Bercher, J., Nguyen, T., Shulga-Morskaya, S., Milstein, S., Shaikh, S., Rollins, J., Golic, M.
ORCID: https://orcid.org/0000-0003-3030-2678, Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, Kräker, K.
ORCID: https://orcid.org/0000-0002-4032-5382, Bendix, I.
ORCID: https://orcid.org/0000-0002-9751-3640, Serdar, M., Napieczynska, H.
ORCID: https://orcid.org/0000-0001-5091-1185, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Gellhaus, A., Thiele, K., Wallukat, G., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, LaMarca, B. and Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080
Journal of Clinical Investigation 130
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1 June 2020
Statins reverse postpartum cardiovascular dysfunction in a rat model of preeclampsia.
Kräker, K.
ORCID: https://orcid.org/0000-0002-4032-5382, O'Driscoll, J.M., Schütte, T.
ORCID: https://orcid.org/0000-0003-4869-2766, Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, Patey, O., Golic, M.
ORCID: https://orcid.org/0000-0003-3030-2678, Geisberger, S.
ORCID: https://orcid.org/0000-0001-6477-1312, Verlohren, S.
ORCID: https://orcid.org/0000-0003-3507-8636, Birukov, A.
ORCID: https://orcid.org/0000-0002-8306-3351, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Thilaganathan, B., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738
Hypertension 75
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January 2020
The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.
Althof, N., Goetzke, C.C.
ORCID: https://orcid.org/0000-0003-3407-7631, Kespohl, M., Voss, K., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Pinkert, S., Kaya, Z., Klingel, K. and Beling, A.
ORCID: https://orcid.org/0000-0002-1826-5248
EMBO Molecular Medicine 10
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1 February 2018
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.
Rathjen, T., Yan, X.
ORCID: https://orcid.org/0000-0002-9135-7915, Kononenko, N.L., Ku, M.C.
ORCID: https://orcid.org/0000-0003-0963-2461, Song, K.
ORCID: https://orcid.org/0000-0001-6216-8157, Ferrarese, L.
ORCID: https://orcid.org/0000-0001-9098-5357, Tarallo, V., Puchkov, D., Kochlamazashvili, G., Brachs, S., Varela, L., Szigeti-Buck, K., Yi, C.X., Schriever, S.C.
ORCID: https://orcid.org/0000-0001-5461-3214, Tattikota, S.G., Carlo, A.S., Moroni, M.
ORCID: https://orcid.org/0000-0002-2389-3468, Siemens, J., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, van der Weyden, L., Birkenfeld, A.L.
ORCID: https://orcid.org/0000-0003-1407-9023, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Poulet, J.F.A.
ORCID: https://orcid.org/0000-0003-0296-5415, Horvath, T.L., Tschöp, M.H., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Trajkovski, M., Haucke, V.
ORCID: https://orcid.org/0000-0003-3119-6993 and Poy, M.N.
ORCID: https://orcid.org/0000-0002-4904-2426
Nature Neuroscience 20
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August 2017
CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia.
Przybyl, L.
ORCID: https://orcid.org/0000-0001-9777-8879, Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738, Golic, M.
ORCID: https://orcid.org/0000-0003-3030-2678, Rugor, J., Solano, M.E., Arck, P.C., Gauster, M., Huppertz, B., Emontzpohl, C., Stoppe, C., Bernhagen, J., Leng, L., Bucala, R., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Weedon-Fekjær, S., Johnsen, G.M., Peetz, D., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Staff, A.C., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134
Circulation Research 119
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24 June 2016
TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure.
An, J., Harms, C., Lättig-Tünnemann, G.
ORCID: https://orcid.org/0000-0001-6485-1136, Sellge, G., Mandic, A.D., Malato, Y., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Endres, M., Trautwein, C. and Donath, S.
Hepatology 56
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August 2012
Mutations in sarcomere protein genes in left ventricular noncompaction.
Klaassen, S., Probst, S., Oechslin, E., Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Krings, G., Schuler, P., Greutmann, M., Huerlimann, D., Yegitbasi, M., Pons, L., Gramlich, M., Drenckhahn, J.D.
ORCID: https://orcid.org/0000-0001-8347-7696, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Berger, F., Jenni, R. and Thierfelder, L.
Circulation 117
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3 June 2008
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
Monti, J., Fischer, J.
ORCID: https://orcid.org/0000-0003-0398-7720, Paskas, S.
ORCID: https://orcid.org/0000-0002-1206-5376, Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Goesele, C., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Fischer, R.
ORCID: https://orcid.org/0000-0002-4828-2882, Schmidt, C., Schirdewan, A., Gross, V., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Maatz, H.
ORCID: https://orcid.org/0000-0002-9232-6272, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Vingron, M., Weldon, S.M., Lindpaintner, K., Hammock, B.D., Rohde, K., Dietz, R., Cook, S.A., Schunck, W.H.
ORCID: https://orcid.org/0000-0001-7965-7731, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Genetics 40
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May 2008
Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy.
Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Plovie, E.R., Ellinor, P.T., Grossmann, K.S., Shin, J.T., Wichter, T., Basson, C.T., Lerman, B.B., Sasse-Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Thierfelder, L., MacRae, C.A. and Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826
American Journal of Human Genetics 79
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December 2006
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Gerull, B.
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The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
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The sorting receptor sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells.
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The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.
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Integrative omics and phase IIa clinical trial identify TNF as key node in autoimmune hepatitis.
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ORCID: https://orcid.org/0009-0007-6933-3849, Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, V., Lu, Y., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Hinds, D.A., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Weidinger, S., Magnusson, P.K., Jorgenson, E., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Boomsma, D.I., Karlsson, R., Almqvist, C., Koppelman, G.H. and Paternoster, L.
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February 2019
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Hemmer, M.C., Wierer, M., Schachtrup, K., Downes, M., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Evans, R.M. and Uhlenhaut, N.H.
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18 January 2019
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Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Grosche, S.
ORCID: https://orcid.org/0000-0002-7658-0932, Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Kalb, B., Blumchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Yürek, S., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Niggemann, B., Beyer, K. and Lee, Y.A.
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October 2018
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Asai, Y., Eslami, A., van Ginkel, C.D., Akhabir, L., Wan, M., Yin, D., Ellis, G., Ben-Shoshan, M., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Martino, D., Ferreira, M.A., Allen, K., Mazer, B., de Groot, H., de Jong, N.W., Gerth van Wijk, R., Dubois, A.E.J., Grosche, S.
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ORCID: https://orcid.org/0000-0001-9973-9742, Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Kalb, B., Beyer, K., Nöthen, M.M., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Chin, R., Cheuk, S., Hoffman, J., Jorgensen, E., Witte, J.S., Melles, R.B., Hong, X., Wang, X., Hui, J., Musk, A.W.B., Hunter, M., James, A.L., Koppelman, G.H., Sandford, A.J., Clarke, A.E. and Daley, D.
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April 2018
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ORCID: https://orcid.org/0000-0002-7242-0341, Chow, K., Khin, E., Tan, J., Chothani, S.P., Ye, L., Rackham, O.J., Ko, N.S., Sahib, N.E., Pua, C.J., Zhen, N.T., Xie, C., Wang, M., Maatz, H.
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ORCID: https://orcid.org/0009-0007-0102-9867, Petretto, E., Schmidt, S., Putoczki, T., Guimarães-Camboa, N., Wakimoto, H., van Heesch, S.
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Nature 552
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7 December 2017
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ORCID: https://orcid.org/0000-0001-9059-1825, Vonk, J.M., Baurecht, H., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, V., van Dongen, J., Lu, Yi, Rueschendorf, F.
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ORCID: https://orcid.org/0000-0002-0626-1821, Burrows, K., Hummel, O.
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ORCID: https://orcid.org/0000-0002-6654-2852, Zhou, W., Hveem, K., Langhammer, A., Holmen, O.L., Løset, M., Abecasis, G.R., Willer, C.J.
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Nature Genetics 49
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December 2017
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ORCID: https://orcid.org/0000-0002-1218-6223, Kumarswamy, R., Thum, T., Yin, X., Mayr, M., Laggerbauer, B. and Engelhardt, S.
Nature Communications 8
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20 November 2017
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.
Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Grosche, S., Kalb, B., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Blümchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Röblitz, H., Yürek, S., Tschirner, S., Hong, X., Wang, X., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Niggemann, B., Beyer, K. and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
Nature Communications 8
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20 October 2017
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Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Adriaens, M.E., Schafer, S., van Deutekom, H.W.M., Lodder, E.M., Ware, J.S., Schneider, V.
ORCID: https://orcid.org/0000-0002-3980-3789, Felkin, L.E., Creemers, E.E., Meder, B., Katus, H.A., Rühle, F., Stoll, M., Cambien, F., Villard, E., Charron, P., Varro, A., Bishopric, N.H., George, A.L., Dos Remedios, C., Moreno-Moral, A., Pesce, F., Bauerfeind, A., Rüschendorf, F.
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ORCID: https://orcid.org/0000-0002-1218-6223
Genome Biology 18
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14 September 2017
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Kammertoens, T.
ORCID: https://orcid.org/0000-0003-3309-5141, Friese, C., Arina, A., Idel, C., Briesemeister, D., Rothe, M.
ORCID: https://orcid.org/0000-0002-6813-4705, Ivanov, A.
ORCID: https://orcid.org/0000-0002-4824-1925, Szymborska, A.
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ORCID: https://orcid.org/0000-0002-7242-0341, Kunz, S.
ORCID: https://orcid.org/0000-0002-0131-3506, Sommermeyer, D., Engels, B.
ORCID: https://orcid.org/0000-0001-9682-2954, Leisegang, M.
ORCID: https://orcid.org/0000-0003-3692-7142, Textor, A., Fehling, H.J., Fruttiger, M., Lohoff, M., Herrmann, A., Yu, H., Weichselbaum, R., Uckert, W., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Gerhardt, H.
ORCID: https://orcid.org/0000-0002-3030-0384, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Schreiber, H. and Blankenstein, T.
ORCID: https://orcid.org/0000-0002-3357-4321
Nature 545
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4 May 2017
Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders.
Lorenz, C.
ORCID: https://orcid.org/0000-0002-7762-8133, Lesimple, P.
ORCID: https://orcid.org/0000-0001-9754-6103, Bukowiecki, R., Zink, A.
ORCID: https://orcid.org/0000-0002-8489-6339, Inak, G., Mlody, B.
ORCID: https://orcid.org/0000-0001-5184-1772, Singh, M.
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ORCID: https://orcid.org/0000-0002-9064-0399 and Prigione, A.
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4 May 2017
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ORCID: https://orcid.org/0000-0002-3980-3789, Faber, A.
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Nature Genetics 49
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January 2017
52 genetic loci influencing myocardial mass.
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ORCID: https://orcid.org/0000-0002-5612-1720, Hernandez, D.G., Hillege, H.L., Hirschhorn, J.N., Hofman, A., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Hwang, S.J., Iorio, A., Kaehoenen, M., Kellis, M., Kolcic, I., Kooner, Is.K., Kooner, J.S., Kors, J.A., Lakatta, E.G., Lage, K., Launer, L.J., Levy, D., Lundby, A., Macfarlane, P.W., May, D., Meitinger, T., Metspalu, A., Nappo, S., Naitza, S., Neph, S., Nord, A.S., Nutile, T., Okin, P.M., Olsen, J.V., Oostra, B.A., Penninger, J.M.
ORCID: https://orcid.org/0000-0002-8194-3777, Pennacchio, L.A., Pers, T.H., Perz, S., Peters, A., Pinto, Y.M., Pfeufer, A., Pilia, M.G., Pramstaller, P.P., Prins, B.P., Raitakari, O.T., Raychaudhuri, S., Rice, K.M., Rossin, E.J., Rotter, J.I., Schaefer, S., Schlessinger, D., Schmidt, C.O., Sehmi, J., Sillje, H.H.W., Sinagra, G., Sinner, M.F., Slowikowski, K., Soliman, E.Z., Spector, T.D., Spiering, W., Stamatoyannopoulos, J.A., Stolk, R.P., Strauch, K., Tan, S.T., Tarasov, K.V., Trinh, B., Uitterlinden, A.G., van den Boogaard, M., van Duijn, C.M., van Gilst, W.H., Viikari, J.S., Visscher, P.M., Vitart, V., Völker, U., Waldenberger, M., Weichenberger, C.X., Westra, H.J., Wijmenga, C., Wolffenbuttel, B.H., Yang, J.
ORCID: https://orcid.org/0000-0003-2001-2474, Bezzina, C.R., Munroe, P.B., Snieder, H., Wright, A.F., Rudan, I., Boyer, L.A., Asselbergs, F.W., van Veldhuisen, D.J., Stricker, B.H., Psaty, B.M., Ciullo, M., Sanna, S., Lehtimäki, T., Wilson, J.F., Bandinelli, S., Alonso, A.
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ORCID: https://orcid.org/0000-0002-4130-7784, Christoffels, V.M., Isaacs, A., Samani, N.J. and de Bakker, P.I.W.
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27 September 2016
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ORCID: https://orcid.org/0000-0001-9197-5871, Petretto, E., MacRae, C. and Cook, S.A.
Nature Communications 7
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8 July 2016
Genome-wide polyadenylation maps reveal dynamic mRNA 3'-end formation in the failing human heart.
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ORCID: https://orcid.org/0000-0002-4472-7119, Cook, S.A., Bezzina, C.R., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, van der Velden, J.
ORCID: https://orcid.org/0000-0001-5224-5788, Elkon, R., Agami, R.
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5 February 2016
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ORCID: https://orcid.org/0000-0002-1218-6223, Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Tamari, M., Hinds, D.A., Glass, D., Brown, S.J., Heinrich, J., Evans, D.M. and Weidinger, S.
Nature Genetics 47
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December 2015
Meta-analysis identifies seven susceptibility loci involved in the atopic march.
Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Esparza-Gordillo, J., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Bauerfeind, A., Strachan, D.P., Spycher, B.D., Baurecht, H., Margaritte-Jeannin, P., Sääf, A., Kerkhof, M., Ege, M., Baltic, S., Matheson, M.C., Li, J., Michel, S., Ang, W.Q., McArdle, W., Arnold, A., Homuth, G., Demenais, F., Bouzigon, E., Söderhäll, C., Pershagen, G., de Jongste, J.C., Postma, D.S., Braun-Fahrlaender, C., Horak, E., Ogorodova, L.M., Puzyrev, V.P., Bragina, E.Y., Hudson, T.J., Morin, C., Duffy, D.L., Marks, G.B., Robertson, C.F., Montgomery, G.W., Musk, B., Thompson, P.J., Martin, N.G., James, A., Sleiman, P., Toskala, E., Rodriguez, E., Fölster-Holst, R., Franke, A., Lieb, W., Gieger, C., Heinzmann, A., Rietschel, E., Keil, T., Cichon, S., Nöthen, M.M., Pennell, C.E., Sly, P.D., Schmidt, C.O., Matanovic, A., Schneider, V.
ORCID: https://orcid.org/0000-0002-3980-3789, Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Holt, P.G., Lau, S., Kabesch, M., Weidinger, S., Hakonarson, H., Ferreira, M.A.R., Laprise, C., Freidin, M.B., Genuneit, J., Koppelman, G.H., Melén, E., Dizier, M.H., Henderson, A.J. and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
Nature Communications 6
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6 November 2015
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.
Binger, K.J.
ORCID: https://orcid.org/0000-0003-1139-3308, Gebhardt, M., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Rintisch, C., Schroeder, A., Neuhofer, W., Hilgers, K., Manzel, A., Schwartz, C., Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Voelkl, J., Schatz, V., Linker, R.A., Lang, F., Voehringer, D., Wright, M.D., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Jantsch, J., Titze, J. and Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Journal of Clinical Investigation 125
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2 November 2015
A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis.
Schaarschmidt, H., Ellinghaus, D., Rodríguez, E., Kretschmer, A., Baurecht, H., Lipinski, S., Meyer-Hoffert, U., Harder, J., Lieb, W., Novak, N., Fölster-Holst, R., Esparza-Gordillo, J., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Ruschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Reischl, E., Waldenberger, M., Gieger, C., Illig, T., Kabesch, M., Zhang, X.J., Xiao, F.L., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Franke, A. and Weidinger, S.
Journal of Allergy and Clinical Immunology 136
(3): 802-806.
September 2015
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.
Hinson, J.T., Chopra, A., Nafissi, N., Polacheck, W.J., Benson, C.C., Swist, S., Gorham, J., Yang, L., Schafer, S., Sheng, C.C., Haghighi, A., Homsy, J., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Church, G., Cook, S.A., Linke, W.A., Chen, C.S., Seidman, J.G. and Seidman, C.E.
Science 349
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28 August 2015
Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo.
Lim, H.W., Uhlenhaut, N.H.
ORCID: https://orcid.org/0000-0002-4220-4779, Rauch, A., Weiner, J., Hübner, S., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Won, K.J., Lazar, M.A., Tuckermann, J. and Steger, D.J.
Genome Research 25
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June 2015
PDE3A mutations cause autosomal dominant hypertension with brachydactyly.
Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Schächterle, C., Weise, A., Stricker, S., Lindschau, C.
ORCID: https://orcid.org/0000-0003-1960-099X, Vaegler, M., Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Toka, H.R., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Krawitz, P.M.
ORCID: https://orcid.org/0000-0002-3194-8625, Parkhomchuk, D., Hecht, J., Hollfinger, I.
ORCID: https://orcid.org/0000-0002-6233-8395, Wefeld-Neuenfeld, Y., Bartels-Klein, E., Mühl, A., Kann, M., Schuster, H., Chitayat, D., Bialer, M.G., Wienker, T.F., Ott, J., Rittscher, K., Liehr, T., Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706, Plessis, G., Tank, J., Mai, K., Naraghi, R., Hodge, R., Hopp, M., Hattenbach, L.O., Busjahn, A., Rauch, A., Vandeput, F., Gong, M.
ORCID: https://orcid.org/0000-0001-7384-3429, Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Haller, H., Mundlos, S., Bilginturan, N., Movsesian, M.A., Klussmann, E.
ORCID: https://orcid.org/0000-0003-4004-5003, Toka, O. and Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755
Nature Genetics 47
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June 2015
Translational regulation shapes the molecular landscape of complex disease phenotypes.
Schafer, S., Adami, E.
ORCID: https://orcid.org/0000-0002-1813-6681, Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Costa Rodrigues, K.E., Kreuchwig, F., Silhavy, J., van Heesch, S.
ORCID: https://orcid.org/0000-0001-9593-1980, Simaite, D., Rajewsky, N.
ORCID: https://orcid.org/0000-0002-4785-4332, Cuppen, E., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Vingron, M., Cook, S.A. and Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Communications 6
: 7200.
26 May 2015
Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.
Roberts, A.M., Ware, J.S., Herman, D.S., Schafer, S., Baksi, J., Bick, A.G., Buchan, R.J., Walsh, R., John, S., Wilkinson, S., Mazzarotto, F., Felkin, L.E., Gong, S., MacArthur, J.A.L., Cunningham, F., Flannick, J., Gabriel, S.B., Altshuler, D.M., Macdonald, P.S., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Keogh, A.M., Hayward, C.S., Banner, N.R., Pennell, D.J., O'Regan, D.P., San, T.R., de Marvao, A., Dawes, T.J.W., Gulati, A., Birks, E.J., Yacoub, M.H., Radke, M.
ORCID: https://orcid.org/0000-0003-0112-9917, Gotthardt, M.
ORCID: https://orcid.org/0000-0003-1788-3172, Wilson, J.G., O'Donnell, C.J., Prasad, S.K., Barton, P.J.R., Fatkin, D., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Seidman, J.G., Seidman, C.E. and Cook, S.A.
Science Translational Medicine 7
(270): 270ra6.
14 January 2015
Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.
Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Illig, T., Irvine, A.D., Kabesch, M., Lee, Y.A.E.
ORCID: https://orcid.org/0000-0002-1817-9163, Lieb, W., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, McLean, W.H.I., Morris, D.W., Mrowietz, U., Nair, R., Nöthen, M.M., Novak, N., O'Regan, G.M., Schreiber, S., Smith, C., Strauch, K., Stuart, P.E., Trembath, R., Tsoi, L.C., Weichenthal, M., Barker, J., Elder, J.T., Weidinger, S., Cordell, H.J. and Brown, S.J.
American Journal of Human Genetics 96
(1): 104-120.
8 January 2015
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.
Günther, C., Kind, B., Reijns, M.A.M., Berndt, N., Martinez-Bueno, M., Wolf, C., Tüngler, V., Chara, O., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Bicknell, L., Blum, S., Krug, C., Schmidt, F., Kretschmer, S., Koss, S., Astell, K.R., Ramantani, G., Bauerfeind, A., Morris, D.L., Cunninghame Graham, D.S., Bubeck, D., Leitch, A., Ralston, S.H., Blackburn, E.A., Gahr, M., Witte, T., Vyse, T.J., Melchers, I., Mangold, E., Nöthen, M.M., Aringer, M., Kuhn, A., Lüthke, K., Unger, L., Bley, A., Lorenzi, A., Isaacs, J.D., Alexopoulou, D., Conrad, K., Dahl, A., Roers, A., Alarcon-Riquelme, M.E., Jackson, A.P. and Lee-Kirsch, M.A.
Journal of Clinical Investigation 125
(1): 413-424.
2 January 2015
Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.
Schubert, J., Siekierska, A., Langlois, M., May, P., Huneau, C., Becker, F., Muhle, H., Suls, A., Lemke, J.R., de Kovel, C.G.F., Thiele, H., Konrad, K., Kawalia, A., Toliat, M.R., Sander, T., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Caliebe, A., Nagel, I., Kohl, B., Kecskes, A., Jacmin, M., Hardies, K., Weckhuysen, S., Riesch, E., Dorn, T., Brilstra, E.H., Baulac, S., Moller, R.S., Hjalgrim, H., Koeleman, B.P.C., Jurkat-Rott, K., Lehman-Horn, F., Roach, J.C., Glusman, G., Hood, L., Galas, D.J., Martin, B., de Witte, P.A.M., Biskup, S., De Jonghe, P., Helbig, I., Balling, R., Nuernberg, P., Crawford, A.D., Esguerra, C.V., Weber, Y.G. and Lerche, H.
Nature Genetics 46
(12): 1327-1332.
December 2014
RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.
Maatz, H.
ORCID: https://orcid.org/0000-0002-9232-6272, Jens, M.
ORCID: https://orcid.org/0000-0002-6660-8743, Liss, M.
ORCID: https://orcid.org/0000-0002-0585-7850, Schafer, S., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Adami, E.
ORCID: https://orcid.org/0000-0002-1813-6681, Rintisch, C., Dauksaite, V.
ORCID: https://orcid.org/0000-0002-9399-4731, Radke, M.H.
ORCID: https://orcid.org/0000-0003-0112-9917, Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751, Barton, P.J.R., Cook, S.A., Rajewsky, N.
ORCID: https://orcid.org/0000-0002-4785-4332, Gotthardt, M.
ORCID: https://orcid.org/0000-0003-1788-3172, Landthaler, M.
ORCID: https://orcid.org/0000-0002-1075-8734 and Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Journal of Clinical Investigation 124
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1 August 2014
AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.
Mojallal, M., Zheng, Y., Hultin, S., Audebert, S., van Harn, T., Johnsson, P., Lenander, C., Fritz, N., Mieth, C., Corcoran, M., Lembo, F., Hallstroem, M., Hartman, J., Mazure, N.M., Weide, T., Grander, D., Borg, J.P., Uhlen, P. and Holmgren, L.
Nature Communications 5
: 4557.
1 August 2014
WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors.
Motamedi, F.J., Badro, D.A., Clarkson, M., Rita Lecca, M., Bradford, S.T., Buske, F.A., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Bräendli, A.W. and Schedl, A.
Nature Communications 5
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17 July 2014
Natural variation of histone modification and its impact on gene expression in the rat genome.
Rintisch, C., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Bauerfeind, A., Schafer, S., Mieth, C., Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Chen, W.
ORCID: https://orcid.org/0000-0003-3263-1627, Cook, S., Cuppen, E., Colomé-Tatché, M., Johannes, F., Jansen, R.C., Neil, H., Werner, M., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Vingron, M. and Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Genome Research 24
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June 2014
Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A.
Auer, F., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Gombert, M., Husemann, P., Ginzel, S., Izraeli, S., Harit, M., Weintraub, M., Weinstein, O.Y., Lerer, I., Stepensky, P., Borkhardt, A. and Hauer, J.
Leukemia 28
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May 2014
Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
Aksoy, I., Giudice, V., Delahaye, E., Wianny, F., Aubry, M., Mure, M., Chen, J., Jauch, R., Bogu, G.K., Nolden, T., Himmelbauer, H., Doss, M.X., Sachinidis, A., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Martinelli, P., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Stanton, L.W., Real, F.X., Bourillot, P.Y. and Savatier, P.
Nature Communications 5
: 3719.
28 April 2014
A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.
Meder, B., Rühle, F., Weis, T., Homuth, G., Keller, A., Franke, J., Peil, B., Bermejo, J.L., Frese, K., Huge, A., Witten, A., Vogel, B., Haas, J., Völker, U., Ernst, F., Teumer, A., Ehlermann, P., Zugck, C., Friedrichs, F., Kroemer, H., Dörr, M., Hoffmann, W., Maisch, B., Pankuweit, S., Ruppert, V., Scheffold, T., Kühl, U., Schultheiss, H.P., Kreutz, R., Ertl, G., Angermann, C., Charron, P., Villard, E., Gary, F., Isnard, R., Komajda, M., Lutz, M., Meitinger, T., Sinner, M.F., Wichmann, H.E., Krawczak, M., Ivandic, B., Weichenhan, D., Gelbrich, G., El-Mokhtari, N.E., Schreiber, S., Felix, S.B., Hasenfuß, G., Pfeufer, A., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Kääb, S., Arbustini, E., Rottbauer, W., Frey, N., Stoll, M. and Katus, H.A.
European Heart Journal 35
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21 April 2014
TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction.
Ragancokova, D., Rocca, E., Oonk, A.M.M., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Rohde, E., Bednarsch, J., Feenstra, I., Pennings, R.J.E., Wende, H.
ORCID: https://orcid.org/0000-0002-9168-8095 and Garratt, A.N.
ORCID: https://orcid.org/0000-0001-9631-3041
Journal of Clinical Investigation 124
(3): 1214-1227.
3 March 2014
Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α.
Brooke, M.A., Longhurst, H.J., Plagnol, V., Kirkby, N.S., Mitchell, J.A., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Warner, T.D., Kelsell, D.P. and MacDonald, T.T.
Gut 63
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January 2014
Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat.
Atanur, S.S., Diaz, A.G., Maratou, K., Sarkis, A., Rotival, M., Game, L., Tschannen, M.R., Kaisaki, P.J., Otto, G.W., John Ma, M.C., Keane, T.M., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1575, Chen, W.
ORCID: https://orcid.org/0000-0003-3263-1627, Guryev, V., Gopalakrishnan, K., Garrett, M.R., Joe, B., Citterio, L., Bianchi, G., McBride, M., Dominiczak, A., Adams, D.J., Serikawa, T., Flicek, P., Cuppen, E., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Petretto, E., Gauguier, D., Kwitek, A., Jacob, H. and Aitman, T.J.
Cell 154
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1 August 2013
A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis.
Esparza-Gordillo, J., Schaarschmidt, H., Liang, L., Cookson, W., Bauerfeind, A., Lee-Kirsch, M.A., Nemat, K., Henderson, J., Paternoster, L., Harper, J.L., Mangold, E., Nothen, M.M., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Kerscher, T., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Matanovic, A., Lau, S., Keil, T., Bauer, C.P., Kurek, M., Ciechanowicz, A., Macek, M., Franke, A., Kabesch, M., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Abecasis, G., Weidinger, S., Moffatt, M. and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
Journal of Allergy and Clinical Immunology 132
(2): 371-377.
August 2013
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.
Arndt, A.K., Schaefer, S., Drenckhahn, J.D.
ORCID: https://orcid.org/0000-0001-8347-7696, Sabeh, M.K., Plovie, E.R., Caliebe, A., Klopocki, E., Musso, G., Werdich, A.A., Kalwa, H., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Padera, R.F., Wassilew, K., Bluhm, J., Harnack, C., Martitz, J., Barton, P.J., Greutmann, M., Berger, F., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Siebert, R., Kramer, H.H., Cook, S.A., Macrae, C.A. and Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912
American Journal of Human Genetics 93
(1): 67-77.
11 July 2013
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.
Baud, A., Hermsen, R., Guryev, V., Stridh, P., Graham, D., McBride, M.W., Foroud, T., Calderari, S., Diez, M., Ockinger, J., Beyeen, A.D., Gillett, A., Abdelmagid, N., Guerreiro-Cacais, A.O., Jagodic, M., Tuncel, J., Norin, U., Beattie, E., Huynh, N., Miller, W.H., Koller, D.L., Alam, I., Falak, S., Osborne-Pellegrin, M., Martinez-Membrives, E., Canete, T., Blazquez, G., Vicens-Costa, E., Mont-Cardona, C., Diaz-Moran, S., Tobena, A., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Zelenika, D., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1575, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Bauerfeind, A., Bihoreau, M.T., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Rintisch, C., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Wheeler, D.A., Worley, K.C., Muzny, D.M., Gibbs, R.A., Lathrop, M., Lansu, N., Toonen, P., Ruzius, F.P., de Bruijn, E., Hauser, H., Adams, D.J., Keane, T., Atanur, S.S., Aitman, T.J., Flicek, P., Malinauskas, T., Jones, E.Y., Ekman, D., Lopez-Aumatell, R., Dominiczak, A.F., Johannesson, M., Holmdahl, R., Olsson, T., Gauguier, D., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Fernandez-Teruel, A., Cuppen, E., Mott, R. and Flint, J.
Nature Genetics 45
(7): 767-775.
July 2013
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
Ellinghaus, D., Baurecht, H., Esparza-Gordillo, J., Rodríguez, E., Matanovic, A., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Schaarschmidt, H., Novak, N., Michel, S., Maintz, L., Werfel, T., Meyer-Hoffert, U., Hotze, M., Prokisch, H., Heim, K., Herder, C., Hirota, T., Tamari, M., Kubo, M., Takahashi, A., Nakamura, Y., Tsoi, L.C., Stuart, P., Elder, J.T., Sun, L., Zuo, X., Yang, S., Zhang, X., Hoffmann, P., Nöthen, M.M., Fölster-Holst, R., Winkelmann, J., Illig, T., Boehm, B.O., Duerr, R.H., Büning, C., Brandt, S., Glas, J., McAleer, M.A., Fahy, C.M., Kabesch, M., Brown, S., McLean, W.H.I., Irvine, A.D., Schreiber, S., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Franke, A. and Weidinger, S.
Nature Genetics 45
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July 2013
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes.
Uhlenhaut, N.H.
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ORCID: https://orcid.org/0000-0002-1218-6223 and Evans, R.M.
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1 November 2012
The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma.
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Journal of Allergy and Clinical Immunology 129
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June 2012
A genetic basis for mechanosensory traits in humans.
Frenzel, H., Bohlender, J., Pinsker, K., Wohlleben, B., Tank, J., Lechner, S.G.
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1 May 2012
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.
Guo, W., Schafer, S., Greaser, M.L., Radke, M.H.
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Nature Medicine 18
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May 2012
Combined RNAi and localization for functionally dissecting long noncoding RNAs.
Chakraborty, D., Kappei, D., Theis, M., Nitzsche, A., Ding, L., Paszkowski-Rogacz, M., Surendranath, V., Berger, N., Schulz, H.
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Nature Methods 9
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12 February 2012
Mutations in FKBP14 cause a variant of Ehlers-Danlos syndrome with progressive kyphoscoliosis, myopathy, and hearing loss.
Baumann, M., Giunta, C., Krabichler, B., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Zoppi, N., Colombi, M., Bittner, R.E., Quijano-Roy, S., Muntoni, F., Cirak, S., Schreiber, G., Zou, Y., Hu, Y., Romero, N.B., Carlier, R.Y., Amberger, A., Deutschmann, A., Straub, V., Rohrbach, M., Steinmann, B., Rostasy, K., Karall, D., Boennemann, C.G., Zschocke, J. and Fauth, C.
American Journal of Human Genetics 90
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10 February 2012
Inflammatory skin and bowel disease linked to ADAM17 deletion.
Blaydon, D.C., Biancheri, P., Di, W.L., Plagnol, V., Cabral, R.M., Brooke, M.A., van Heel, D.A., Ruschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Toynbee, M., Walne, A., O'Toole, E.A., Martin, J.E., Lindley, K., Vulliamy, T., Abrams, D.J., MacDonald, T.T., Harper, J.I. and Kelsell, D.P.
New England Journal of Medicine 365
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20 October 2011
Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.
McDermott-Roe, C., Ye, J., Ahmed, R., Sun, X.M., Serafin, A., Ware, J., Bottolo, L., Muckett, P., Canas, X., Zhang, J., Rowe, G.C., Buchan, R., Lu, H., Braithwaite, A., Mancini, M., Hauton, D., Marti, R., Garcia-Arumi, E., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Jacob, H., Serikawa, T., Zidek, V., Papousek, F., Kolar, F., Cardona, M., Ruiz-Meana, M., Garcia-Dorado, D., Comella, J.X., Felkin, L.E., Barton, P.J., Arany, Z., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Petretto, E., Sanchis, D. and Cook, S.A.
Nature 478
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6 October 2011
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Petretto, E., Wallace, C., Bottolo, L., Rotival, M., Lu, H., Li, Y., Sarwar, R., Langley, S.R., Bauerfeind, A., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Paskas, S.
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ORCID: https://orcid.org/0000-0002-4483-1557, Cooper, J., Buchan, R., Gray, E.E., Cyster, J.G., Braund, P., Gracey, J., Krishnan, U., Moore, J.S., Nelson, C.P., Pollard, H., Attwood, T., Crisp-Hihn, A., Foad, N., Jolley, J., Lloyd-Jones, H., Muir, D., Murray, E., O'Leary, K., Rankin, A., Sambrook, J., Godfroy, T., Brocheton, J., Proust, C., Schmitz, G., Heimerl, S., Lugauer, I., Belz, S., Gulde, S., Linsel-Nitschke, P., Sager, H., Schroeder, L., Lundmark, P., Syvannen, A.C., Neudert, J., Scholz, M., Deloukas, P., Gray, E., Gwilliams, R., Niblett, D., Erdmann, J., Hengstenberg, C., Maouche, S., Ouwehand, W.H., Rice, C.M., Samani, N.J., Schunkert, H., Goodall, A.H., Schulz, H.
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Nature 467
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23 September 2010
The genome sequence of the spontaneously hypertensive rat: analysis and functional significance.
Atanur, S.S., Birol, I., Guryev, V., Hirst, M., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Morrissey, C., Behmoaras, J., Fernandez-Suarez, X.M., Johnson, M.D., McLaren, W.M., Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Petretto, E., Plessy, C., Rockland, K.S., Rockland, C., Saar, K., Zhao, Y., Carninci, P., Flicek, P., Kurtz, T., Cuppen, E., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Jones, S.J., Birney, E. and Aitman, T.J.
Genome Research 20
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June 2010
Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease.
Joutel, A., Monet-Lepretre, M., Gosele, C., Baron-Menguy, C., Hammes, A.
ORCID: https://orcid.org/0000-0003-1663-8378, Schmidt, S., Lemaire-Carrette, B., Domenga, V., Schedl, A., Lacombe, P. and Huebner, N.
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Journal of Clinical Investigation 120
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1 February 2010
A novel active endogenous retrovirus family contributes to genome variability in rat inbred strains.
Wang, Y.
ORCID: https://orcid.org/0000-0001-8269-5296, Liska, F., Gosele, C., Sedova, L., Kren, V., Krenova, D., Ivics, Z.
ORCID: https://orcid.org/0000-0002-7803-6658, Huebner, N.
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Genome Research 20
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January 2010
CLCN2 variants in idiopathic generalized epilepsy.
Kleefuss-Lie, A., Friedl, W., Cichon, S., Haug, K., Warnstedt, M., Alekov, A., Sander, T., Ramirez, A., Poser, B., Maljevic, S., Hebeisen, S., Kubisch, C., Rebstock, J., Horvath, S., Hallmann, K., Dullinger, J.S., Rau, B., Haverkamp, F., Beyenburg, S., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Janz, D., Giese, B., Muller-Newen, G., Propping, P., Elger, C.E., Fahlke, C. and Lerche, H.
Nature Genetics 41
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September 2009
RNASET2-deficient cystic leukoencephalopathy resembles congenital cytomegalovirus brain infection.
Henneke, M., Diekmann, S., Ohlenbusch, A., Kaiser, J., Engelbrecht, V., Kohlschuetter, A., Kraetzner, R., Madruga-Garrido, M., Mayer, M., Opitz, L., Rodriguez, D., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Schumacher, J., Thiele, H., Thoms, S., Steinfeld, R., Nuernberg, P. and Gaertner, J.
Nature Genetics 41
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July 2009
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
Ding, L., Paszkowski-Rogacz, M., Nitzsche, A., Slabicki, M.M., Heninger, A.K., Vries, I.D., Kittler, R., Junqueira, M., Shevchenko, A., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Doss, M.X., Sachinidis, A., Hescheler, J., Iacone, R., Anastassiadis, K., Stewart, A.F., Pisabarro, M.T., Caldarelli, A., Poser, I., Theis, M. and Buchholz, F.
Cell Stem Cell 4
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8 May 2009
A common variant on chromosome 11q13 is associated with atopic dermatitis.
Esparza-Gordillo, J., Weidinger, S., Foelster-Holst, R., Bauerfeind, A., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Rohde, K., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Schulz, F., Kerscher, T., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Wahn, U., Schreiber, S., Franke, A., Vogler, R., Heath, S., Baurecht, H., Novak, N., Rodriguez, E., Illig, T., Lee-Kirsch, M.A., Ciechanowicz, A., Kurek, M., Piskackova, T., Macek, M., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163 and Ruether, A.
Nature Genetics 41
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May 2009
Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation.
Huck, K., Feyen, O., Niehues, T., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Laws, H.J., Telieps, T., Knapp, S., Wacker, H.H., Meindl, A., Jumaa, H. and Borkhardt, A.
Journal of Clinical Investigation 119
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May 2009
Mutations in SPINT2 cause a syndromic form of congenital sodium diarrhea.
Heinz-Erian, P., Mueller, T., Krabichler, B., Schranz, M., Becker, C., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Nuernberg, P., Rossier, B., Vujic, M., Booth, I.W., Holmberg, C., Wijmenga, C., Grigelioniene, G., Kneepkens, C.M., Rosipal, S., Mistrik, M., Kappler, M., Michaud, L., Doczy, L.C., Siu, V.M., Krantz, M., Zoller, H., Utermann, G. and Janecke, A.R.
American Journal of Human Genetics 84
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13 February 2009
15q13.3 microdeletions increase risk of idiopathic generalized epilepsy.
Helbig, I., Mefford, H.C., Sharp, A.J., Guipponi, M., Fichera, M., Franke, A., Muhle, H., de Kovel, C., Baker, C., von Spiczak, S., Kron, K.L., Steinich, I., Kleefuss-Lie, A.A., Leu, C., Gaus, V., Schmitz, B., Klein, K.M., Reif, P.S., Rosenow, F., Weber, Y., Lerche, H., Zimprich, F., Urak, L., Fuchs, K., Feucht, M., Genton, P., Thomas, P., Visscher, F., de Haan, G.J., Moller, R.S., Hjalgrim, H., Luciano, D., Wittig, M., Nothnagel, M., Elger, C.E., Nuernberg, P., Romano, C., Malafosse, A., Koeleman, B.P.C., Lindhout, D., Stephani, U., Schreiber, S., Eichler, E.E. and Sander, T.
Nature Genetics 41
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February 2009
The Met allele of the BDNF Val66Met polymorphism is associated with increased BDNF serum concentrations.
Lang, U.E., Hellweg, R., Sander, T. and Gallinat, J.
Molecular Psychiatry 14
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February 2009
PTHR1 loss-of-function mutations in familial, nonsyndromic primary failure of tooth eruption.
Decker, E., Stellzig-Eisenhauer, A., Fiebig, B.S., Rau, C., Kress, W., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Grimm, T. and Weber, B.H.
American Journal of Human Genetics 83
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12 December 2008
A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults.
Gotthardt, D., Runz, H., Keitel, V., Fischer, C., Flechtenmacher, C., Wirtenberger, M., Weiss, K.H., Imparato, S., Braun, A., Hemminki, K., Stremmel, W., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Stiehl, A., Kubitz, R., Burwinkel, B., Schirmacher, P., Knisely, A.S., Zschocke, J. and Sauer, P.
Hepatology 48
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October 2008
Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension.
Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Churchill, P.C., Churchill, M.C., Viklicky, O., Kazdova, L., Aitman, T.J., Petretto, E., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Wallace, C.A., Zimdahl, H., Zidek, V., Landa, V., Dunbar, J., Bidani, A., Griffin, K., Qi, N., Maxova, M., Kren, V., Mlejnek, P., Wang, J. and Kurtz, T.W.
Nature Genetics 40
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August 2008
Progress and prospects in rat genetics: a community view.
Aitman, T.J., Critser, J.K., Cuppen, E., Dominiczak, A., Fernandez-Suarez, X.M., Flint, J., Gauguier, D., Geurts, A.M., Gould, M., Harris, P.C., Holmdahl, R., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Izsvak, Z.
ORCID: https://orcid.org/0000-0002-2053-2384, Jacob, H.J., Kuramoto, T., Kwitek, A.E., Marrone, A., Mashimo, T., Moreno, C., Mullins, J., Mullins, L., Olsson, T., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Riley, L., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Serikawa, T., Shull, J.D., Szpirer, C., Twigger, S.N., Voigt, B. and Worley, K.C.
Nature Genetics 40
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May 2008
Distribution and functional impact of DNA copy number variation in the rat.
Guryev, V., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Adamovic, T., Verheul, M., van Heesch, S.
ORCID: https://orcid.org/0000-0001-9593-1980, Cook, S., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Aitman, T., Jacob, H., Shull, J.D., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Cuppen, E.
Nature Genetics 40
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May 2008
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
Monti, J., Fischer, J.
ORCID: https://orcid.org/0000-0003-0398-7720, Paskas, S.
ORCID: https://orcid.org/0000-0002-1206-5376, Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Goesele, C., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Fischer, R.
ORCID: https://orcid.org/0000-0002-4828-2882, Schmidt, C., Schirdewan, A., Gross, V., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Maatz, H.
ORCID: https://orcid.org/0000-0002-9232-6272, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Vingron, M., Weldon, S.M., Lindpaintner, K., Hammock, B.D., Rohde, K., Dietz, R., Cook, S.A., Schunck, W.H.
ORCID: https://orcid.org/0000-0001-7965-7731, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Genetics 40
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May 2008
Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass.
Petretto, E., Sarwar, R., Grieve, I., Lu, H., Kumaran, M.K., Muckett, P.J., Mangion, J., Schroen, B., Benson, M., Punjabi, P.P., Prasad, S.K., Pennell, D.J., Kiesewetter, C., Tasheva, E.S., Corpuz, L.M., Webb, M.D., Conrad, G.W., Kurtz, T.W., Kren, V., Fischer, J.
ORCID: https://orcid.org/0000-0003-0398-7720, Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Pinto, Y.M., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Aitman, T.J. and Cook, S.A.
Nature Genetics 40
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May 2008
SNP and haplotype mapping for genetic analysis in the rat.
Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Beck, A., Bihoreau, M.T., Birney, E., Brocklebank, D., Chen, Y., Cuppen, E., Demonchy, S., Dopazo, J., Flicek, P., Foglio, M., Fujiyama, A., Gut, I.G., Gauguier, D., Guigo, R., Guryev, V., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Jahn, N., Klages, S., Kren, V., Kube, M., Kuhl, H., Kuramoto, T., Kuroki, Y., Lechner, D., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Lopez-Bigas, N., Lathrop, G.M., Mashimo, T., Medina, I., Mott, R., Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Perrier-Cornet, J.A., Platzer, M., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Reinhardt, R., Sakaki, Y., Schilhabel, M., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Serikawa, T., Shikhagaie, M., Tatsumoto, S., Taudien, S., Toyoda, A., Voigt, B., Zelenika, D., Zimdahl, H. and Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Genetics 40
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May 2008
G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth.
Pasternack, S.M., von Kuegelgen, I., Aboud, K.A., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Voss, K., Hillmer, A.M., Molderings, G.J., Franz, T., Ramirez, A., Nuernberg, P., Noethen, M.M. and Betz, R.C.
Nature Genetics 40
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March 2008
Genome-wide analysis indicates more Asian than Melanesian ancestry of Polynesians.
Kayser, M., Lao, O., Saar, K., Brauer, S., Wang, X., Nuernberg, P., Trent, R.J. and Stoneking, M.
American Journal of Human Genetics 82
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10 January 2008
Association and linkage of allelic variants of the dopamine transporter gene in ADHD.
Friedel, S., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Sauer, S.
ORCID: https://orcid.org/0000-0002-4794-3693, Dempfle, A., Walitza, S., Renner, T., Romanos, M., Freitag, C., Seitz, C., Palmason, H., Scherag, A., Windemuth-Kieselbach, C., Schimmelmann, B.G., Wewetzer, C., Meyer, J., Warnke, A., Lesch, K.P., Reinhardt, R., Herpertz-Dahlmann, B., Linder, M., Hinney, A., Remschmidt, H., Schaefer, H., Konrad, K., Huebner, N.
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Molecular Psychiatry 12
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October 2007
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.
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Familial chilblain lupus, a monogenic form of cutaneous lupus erythematosus, maps to chromosome 3p.
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Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.
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Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2.
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Mutations in the gene encoding gap junction protein alpha 12 (connexin 46.6) cause Pelizaeus-Merzbacher-like disease.
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Lancet Oncology 26
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Preclinical in vitro and in vivo evidence for targeting CD74 as an effective treatment strategy for cutaneous T-cell lymphomas.
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High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA): a single-arm, phase 2 trial.
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Nature Communications 14
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The DNA methylation status of the TERT promoter differs between subtypes of mature B-cell lymphomas.
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Nivolumab and doxorubicin, vinblastine, and dacarbazine in early-stage unfavorable Hodgkin Lymphoma: final analysis of the randomized german Hodgkin study group phase II NIVAHL trial.
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A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
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Science Immunology 8
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January 2023
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.
Garces de Los Fayos Alonso, I., Zujo, L., Wiest, I., Kodajova, P., Timelthaler, G., Edtmayer, S., Zrimšek, M., Kollmann, S., Giordano, C., Kothmayer, M., Neubauer, H.A., Dey, S., Schlederer, M., Schmalzbauer, B.S., Limberger, T., Probst, C., Pusch, O., Högler, S., Tangermann, S., Merkel, O., Schiefer, A.I., Kornauth, C., Prutsch, N., Zimmerman, M., Abraham, B., Anagnostopoulos, J., Quintanilla-Martinez, L., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Wolf, P., Stoiber, D., Staber, P.B., Egger, G., Klapper, W., Woessmann, W., Look, T.A., Gunning, P., Turner, S.D., Moriggl, R., Lagger, S. and Kenner, L.
Molecular Cancer 21
(1): 172.
31 August 2022
Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R., Dickinson, M., Purtill, D., Barba, P., Santoro, A., Hamad, N., Kato, K., Sureda, A., Greil, R., Thieblemont, C., Morschhauser, F., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Flinn, I., Rabitsch, W., Kwong, Y.L., Kersten, M.J, Minnema, M.C., Holte, H., Chan, E.H.L., Martinez-Lopez, J., Müller, A.M.S., Maziarz, R.T., McGuirk, J.P., Bachy, E., Le Gouill, S., Dreyling, M., Harigae, H., Bond, D., Andreadis, C., McSweeney, P., Kharfan-Dabaja, M., Newsome, S., Degtyarev, E., Awasthi, R., Del Corral, C., Andreola, G., Masood, A., Schuster, S.J., Jäger, U., Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386
(7): 629-639.
17 February 2022
Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group.
Damaschin, C., Goergen, H., Kreissl, S., Plütschow, A., Breywisch, F., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Meissner, J., Sökler, M., Topp, M.S., Vucinic, V., Zimmermann, A., von Tresckow, B., Fuchs, M., Engert, A., Borchmann, P. and Eichenauer, D.A.
ORCID: https://orcid.org/0000-0002-1927-3514
Leukemia 36
(2): 580-582.
February 2022
Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma.
Liang, H.C.
ORCID: https://orcid.org/0000-0003-2612-3714, Costanza, M.
ORCID: https://orcid.org/0000-0002-8959-1083, Prutsch, N., Zimmerman, M.W.
ORCID: https://orcid.org/0000-0003-2489-3889, Gurnhofer, E., Montes-Mojarro, I.A.
ORCID: https://orcid.org/0000-0003-0636-7623, Abraham, B.J.
ORCID: https://orcid.org/0000-0001-8085-3027, Prokoph, N.
ORCID: https://orcid.org/0000-0002-6429-9895, Stoiber, S.
ORCID: https://orcid.org/0000-0003-3293-867X, Tangermann, S., Lobello, C., Oppelt, J.
ORCID: https://orcid.org/0000-0002-3076-4840, Anagnostopoulos, I., Hielscher, T., Pervez, S., Klapper, W.
ORCID: https://orcid.org/0000-0001-7208-4117, Zammarchi, F., Silva, D.A.
ORCID: https://orcid.org/0000-0002-3195-9009, Garcia, K.C.
ORCID: https://orcid.org/0000-0001-9273-0278, Baker, D.
ORCID: https://orcid.org/0000-0001-7896-6217, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Fend, F.
ORCID: https://orcid.org/0000-0002-5496-293X, Pospíšilová, Š., Janiková, A., Wallwitz, J., Stoiber, D., Simonitsch-Klupp, I., Cerroni, L., Pileri, S., de Leval, L.
ORCID: https://orcid.org/0000-0003-3994-516X, Sibon, D., Fataccioli, V., Gaulard, P., Assaf, C., Knörr, F., Damm-Welk, C., Woessmann, W., Turner, S.D.
ORCID: https://orcid.org/0000-0002-8439-4507, Look, A.T.
ORCID: https://orcid.org/0000-0001-7851-8617, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Kenner, L.
ORCID: https://orcid.org/0000-0003-2184-1338 and Merkel, O.
ORCID: https://orcid.org/0000-0001-5089-344X
Nature Communications 12
(1): 5577.
22 September 2021
Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1.
Reinke, S., Bröckelmann, P.J., Iaccarino, I., Garcia-Marquez, M., Borchmann, S., Jochims, F., Kotrova, M., Pal, K., Brüggemann, M., Hartmann, E., Sasse, S., Kobe, C., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Soekler, M., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Bormann, M., Zimmermann, A., Richter, J., Fuchs, M., von Tresckow, B., Borchmann, P., Schlößer, H., von Bergwelt-Baildon, M., Rosenwald, A., Engert, A. and Klapper, W.
Blood 136
(25): 2851-2863.
17 December 2020
The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Scholz, F.
ORCID: https://orcid.org/0000-0002-0253-081X, Grau, M., Menzel, L.
ORCID: https://orcid.org/0000-0002-3816-6255, Graband, A.
ORCID: https://orcid.org/0000-0002-9038-0734, Zapukhlyak, M.
ORCID: https://orcid.org/0000-0002-2635-6940, Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Lenz, G., Rehm, A.
ORCID: https://orcid.org/0000-0001-7490-1950 and Höpken, U.E.
ORCID: https://orcid.org/0000-0002-0776-4893
Proceedings of the National Academy of Sciences of the United States of America 117
(42): 26328-26339.
20 October 2020
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V.
ORCID: https://orcid.org/0000-0002-0077-1935, Berruezo-Llacuna, M., Altwasser, R.
ORCID: https://orcid.org/0009-0002-6216-6068, Winkler, W.
ORCID: https://orcid.org/0000-0001-8807-9259, Sundaravinayagam, D.
ORCID: https://orcid.org/0000-0003-0717-7530, Balasubramanian, S.
ORCID: https://orcid.org/0000-0003-1830-5737, Caganova, M.
ORCID: https://orcid.org/0000-0002-4576-6574, Graf, R.
ORCID: https://orcid.org/0000-0002-5400-9938, Rahjouei, A.
ORCID: https://orcid.org/0000-0003-3973-6333, Henke, M.T.
ORCID: https://orcid.org/0000-0001-6572-1667, Driesner, M., Keller, L., Prigione, A.
ORCID: https://orcid.org/0000-0001-9457-1952, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117 and Di Virgilio, M.
ORCID: https://orcid.org/0000-0001-5189-0793
Journal of Experimental Medicine 217
(10): e20200137.
5 October 2020
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage.
Toboso-Navasa, A.
ORCID: https://orcid.org/0000-0001-8560-1507, Gunawan, A.
ORCID: https://orcid.org/0000-0002-4136-3620, Morlino, G., Nakagawa, R.
ORCID: https://orcid.org/0000-0003-2511-0444, Taddei, A., Damry, D., Patel, Y.
ORCID: https://orcid.org/0000-0003-1787-0726, Chakravarty, P., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Kassiotis, G., Brink, R.
ORCID: https://orcid.org/0000-0002-9586-3655, Eilers, M. and Calado, D.P.
ORCID: https://orcid.org/0000-0001-8239-7184
Journal of Experimental Medicine 217
(7): e20191933.
6 July 2020
Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial.
Bröckelmann, P.J., Goergen, H., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Meissner, J., Ordemann, R., Halbsguth, T.V., Sasse, S., Sökler, M., Kerkhoff, A., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Hüttmann, A., Bormann, M., Zimmermann, A., Mettler, J., Fuchs, M., von Tresckow, B., Baues, C., Rosenwald, A., Klapper, W., Kobe, C., Borchmann, P. and Engert, A.
JAMA Oncology 6
(6): 872-880.
June 2020
Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V.
ORCID: https://orcid.org/0000-0003-3606-6792, McShane, E.
ORCID: https://orcid.org/0000-0002-7806-2063, Schulz-Beiss, K.W., Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Schleussner, N.
ORCID: https://orcid.org/0009-0001-3549-5600, Kolesnichenko, M.
ORCID: https://orcid.org/0000-0001-7366-9061, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414, Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A.
ORCID: https://orcid.org/0000-0002-0468-0117, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413 and Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129
Blood 133
(13): 1489-1494.
28 March 2019
Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
Eichenauer, D.A., Plütschow, A., Kreissl, S., Sökler, M., Hellmuth, J.C., Meissner, J., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Topp, M.S., Behringer, K., Klapper, W., Kuhnert, G., Dietlein, M., Kobe, C., Fuchs, M., Diehl, V., Engert, A. and Borchmann, P.
Lancet Oncology 18
(12): 1680-1687.
December 2017
Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.
Wurster, K.D., Hummel, F., Richter, J., Giefing, M., Hartmann, S., Hansmann, M.L., Kreher, S., Köchert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Krappmann, D.
ORCID: https://orcid.org/0000-0001-7640-3234, Klapper, W., Hummel, M., Wenzel, S.S., Lenz, G., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Siebert, R. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Leukemia 31
(3): 602-613.
March 2017
Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J., Neuenschwander, M.
ORCID: https://orcid.org/0000-0002-3114-7975, Yu, Y.
ORCID: https://orcid.org/0000-0003-1928-2514, Däbritz, J.H.M., Neuendorff, N.R., Schleich, K., Bittner, A.
ORCID: https://orcid.org/0000-0001-6434-0950, Milanovic, M.
ORCID: https://orcid.org/0000-0003-1860-6003, Beuster, G., Radetzki, S.
ORCID: https://orcid.org/0000-0003-2688-2868, Specker, E.
ORCID: https://orcid.org/0000-0002-9471-9520, Reimann, M.
ORCID: https://orcid.org/0000-0002-7876-0128, Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Lohneis, P., Hummel, M., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, von Kries, J.P.
ORCID: https://orcid.org/0000-0003-4716-4988, Lee, S.
ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A.
ORCID: https://orcid.org/0000-0002-4731-2226
Blood 129
(1): 71-81.
5 January 2017
The IL-15 cytokine system provides growth and survival signals in hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells.
Ullrich, K., Blumenthal-Barby, F., Lamprecht, B., Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Lenze, D., Hummel, M., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044
Leukemia 29
(5): 1213-1218.
May 2015
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A., Grau, M., Erdmann, T., Merkel, O., Sobhiafshar, U., Anagnostopoulos, I., Hummel, M., Siegert, A., Hayford, C., Madle, H., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Fichtner, I., Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Dirnhofer, S., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Emre, N.C.T., Rosenwald, A., Ott, G., Lenz, P., Tzankov, A. and Lenz, G.
Blood 125
(1): 124-132.
1 January 2015
Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A.
ORCID: https://orcid.org/0000-0001-7490-1950, Gätjen, M., Gerlach, K., Scholz, F.
ORCID: https://orcid.org/0000-0002-0253-081X, Mensen, A., Gloger, M., Heinig, K., Lamprecht, B., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Bégay, V.
ORCID: https://orcid.org/0000-0002-9002-4211, Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X, Lipp, M.
ORCID: https://orcid.org/0000-0002-0087-2672, Dörken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Höpken, U.E.
ORCID: https://orcid.org/0000-0002-0776-4893
Nature Communications 5
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30 September 2014
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P.
ORCID: https://orcid.org/0000-0001-8239-7184, Sasaki, Y., Godinho, S.A., Pellerin, A., Köchert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Sleckman, B.P., de Alboran, I.M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Rodig, S. and Rajewsky, K.
ORCID: https://orcid.org/0000-0002-6633-6370
Nature Immunology 13
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November 2012
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A., Moebs, M., Ullmann, R., Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Kreher, S., Lamprecht, B., Anagnostopoulos, I., Hummel, M., Richter, J., Beyer, M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Klemke, C.D., Stein, H., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Sterry, W., Schrock, E., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413 and Assaf, C.
Journal of Experimental Medicine 208
(8): 1585-1593.
1 August 2011
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B., Walter, K., Kreher, S., Kumar, R., Hummel, M., Lenze, D., Koechert, K.
ORCID: https://orcid.org/0000-0002-5548-2022, Bouhlel, M.A., Richter, J., Soler, E., Stadhouders, R., Joehrens, K., Wurster, K.D., Callen, D.F., Harte, M.F., Giefing, M., Barlow, R., Stein, H., Anagnostopoulos, I., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Cockerill, P.N., Siebert, R., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Bonifer, C. and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Nature Medicine 16
(5): 571-579, 1p following 579.
May 2010
The dangers of transcription.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413 and Misteli, T.
Cell 139
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11 December 2009
C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Pal, R., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Galson, D.L., Gries, M., Li, S., Johrens, K., Anagnostopoulos, I., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Mapara, M.Y., Borghesi, L., Kardava, L., Roodman, G.D., Milcarek, C. and Lentzsch, S.
Blood 114
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29 October 2009
Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B., Kreher, S., Anagnostopoulos, I., Joehrens, K., Monteleone, G., Jundt, F., Stein, H., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413
Blood 112
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15 October 2008
Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Martin-Subero, J.I., Wlodarska, I., Bastard, C., Picquenot, J.M., Hoeppner, J., Giefing, M., Klapper, W., Siebert, R., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Joos, S., Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 108
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1 July 2006
Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Hummel, M., Truss, M., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Joehrens, K., Hagemeier, C., Bommert, K., Stein, H., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Bargou, R.C.
Blood 107
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15 March 2006
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Hummel, F., Hummel, M., Wollert-Wulf, B.
ORCID: https://orcid.org/0009-0000-0257-4049, Lusatis, S., Anagnostopoulos, I., Lietz, A., Sigvardsson, M., Jundt, F., Joehrens, K., Bommert, K., Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Nature Immunology 7
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February 2006
Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Joehrens, K., Joos, S., Lietz, A., Hummel, F., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Jundt, F., Anagnostopoulos, I., Bommert, K., Lichter, P., Stein, H., Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129 and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 106
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25 August 2005
A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F., Raetzel, N., Mueller, C., Calkhoven, C.F., Kley, K., Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Lietz, A., Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 106
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1 January 2005
Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Mapara, M.Y., Lemke, B., Stirling, D., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643, Zenke, M. and Lentzsch, S.
Blood 105
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1 January 2005
c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Lietz, A., Anagnostopoulos, I., Hummel, F., Wiesner, B., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Jundt, F., Hirsch, B., Joehrens-Leder, K., Vornlocher, H.P., Bommert, K., Stein, H. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Journal of Experimental Medicine 199
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19 April 2004
Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S.
ORCID: https://orcid.org/0000-0001-9626-1413, Lietz, A., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Hinz, M.
ORCID: https://orcid.org/0000-0003-2611-4121, Jundt, F., Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Bommert, K. and Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643
Blood 102
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1 August 2003
Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S., Gries, M., Janz, M.
ORCID: https://orcid.org/0000-0002-1127-0044, Bargou, R., Doerken, B.
ORCID: https://orcid.org/0000-0001-7991-3643 and Mapara, M.Y.
Blood 101
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1 May 2003
Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
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Kaminski, Michael (BIMSB)
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In vivo base editing reduces liver cysts in autosomal dominant polycystic kidney disease.
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ORCID: https://orcid.org/0009-0008-0164-3346, Wendlinger, Sarah
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Synthetic genetic circuits to uncover the OCT4 trajectories of successful reprogramming of human fibroblasts.
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HNF1B alters an evolutionarily conserved nephrogenic program of target genes.
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Tuning the 3D microenvironment of reprogrammed tubule cells enhances biomimetic modeling of polycystic kidney disease.
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Nature Nanotechnology 17
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Nature Biomedical Engineering 5
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July 2021
A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection.
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Kaplan, Oktay
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Kaplan, O.I.
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Blood Cancer Discovery
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The protein phosphatase inhibitor LB100 targets the mesenchymal lineage of pancreatic ductal adenocarcinoma.
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ORCID: https://orcid.org/0000-0002-8485-1958, Na, Il-Kang
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Aberrant SUMOylation restricts the targetable cancer immunopeptidome.
Demel, Uta M.
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Rhein, Simone
ORCID: https://orcid.org/0000-0002-9445-2352, Çakmak-Görür, Neşe
ORCID: https://orcid.org/0000-0001-7857-2461, Grunert, Corinna
ORCID: https://orcid.org/0000-0001-8376-8629, Al-Tabatabaee, Sarah Hayder Jalal, Serin, Nazli, Leisegang, Matthias
ORCID: https://orcid.org/0000-0003-3692-7142, Timiliotis, Stefanos, Ohlmeier, Luisa Sophie
ORCID: https://orcid.org/0000-0002-3381-3003, Freund, Cäcilia
ORCID: https://orcid.org/0000-0002-9260-0032, Willimsky, Gerald
ORCID: https://orcid.org/0000-0002-9693-948X, Konietschke, Frank, Kieback, Elisa
ORCID: https://orcid.org/0000-0003-3831-2846, Tasian, Sarah K., Chapuy, Bjoern, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Blankenstein, Thomas
ORCID: https://orcid.org/0000-0002-3357-4321, Pezzutto, Antonio
ORCID: https://orcid.org/0000-0002-3246-4470 and Busse, Antonia
ORCID: https://orcid.org/0000-0002-3470-6947
Blood 147
(10): 1058-1069.
5 March 2026
Heart failure therapy in patients with advanced cancer receiving specialized palliative care (EMPATICC trial).
Anker, Markus S.
ORCID: https://orcid.org/0000-0002-4406-8555, Mahabadi, Amir A., Totzeck, Matthias, Tewes, Mitra, Shahzeb Khan, Muhammad, Mincu, Raluca I., Hendgen-Cotta, Ulrike B., Michel, Lars, Mathew, Baicy, Drescher, Ophelia, Schuler, Martin, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Rieger, Kathrin, Ahn, Johann, Bullinger, Lars
ORCID: https://orcid.org/0000-0002-5890-5510, Modest, Dominik P., Denecke, Corinna, Kretzler, Lucie, Ramer, Luisa V., Krug, Danara, Landmesser, Ulf, Lehmann, Lorenz, Frey, Norbert, Bercker, Sven, Laufs, Ulrich, Böhm, Michael, Mahfoud, Felix
ORCID: https://orcid.org/0000-0002-4425-549X, Merkely, Bela, Diek, Monika, Butler, Javed, Veiser, Anja, Heise, Tim, Hellmich, Martin, Placzek, Marius, Friede, Tim
ORCID: https://orcid.org/0000-0001-5347-7441, Anker, Stefan D. and Rassaf, Tienush
European Heart Journal 47
(9): 1034-1046.
1 March 2026
Targeting mutual dependence of phosphatidylinositol-3-kinase α/δ and small ubiquitin-like modifier signaling in pancreatic cancer.
Köse, Hazal, Schneeweis, Christian, Putze, Philipp, Contreras, Constanza Tapia, Ferreiro, Laura, Witte, Leonie, Deidda, Ilaria, Herzberg, Frederik, Ebert, Sophie, Jakubik, Juraj, Moldaner, Leoni, Todorovic, Jovan, Träger, Isabelle, Zang, Chuanbing, Demel, Uta M.
ORCID: https://orcid.org/0000-0002-6480-4185, Hessmann, Elisabeth, Kirchner, Marieluise
ORCID: https://orcid.org/0000-0002-7049-534X, Rhein, Simone
ORCID: https://orcid.org/0000-0002-9445-2352, Hoffmann, Jens
ORCID: https://orcid.org/0000-0003-3880-1658, Tatarova, Zuzana, Ghadimi, Michael, Saur, Dieter, Kappert, Kai, Mertins, Philipp
ORCID: https://orcid.org/0000-0002-2245-528X, Schneider, Günter, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958 and Wirth, Matthias
ORCID: https://orcid.org/0000-0002-8340-0872
Gastroenterology 170
(2): 315-329.
February 2026
Teclistamab-induced rapid remission in refractory anti-Jo-1 antisynthetase syndrome.
Phithak, Elpida, Albach, Fredrik N., Minopoulou, Ioanna, Biesen, Robert, Kleyer, Arnd, Wiebe, Edgar, Siegert, Elise, Scholz, Veronika, Rehm, Marie, Cheng, Qingyu, Sattler, Arne, Bianco, Stefano, Fleischmann, Anja, Hermann, Kay-Geert, Walter-Rittel, Thula, Wagner, Moritz, Zernicke, Jan, Casteleyn, Vincent, Nielsen, Martin, Rose, Thomas, Busse, Antonia
ORCID: https://orcid.org/0000-0002-3470-6947, Hütter-Krönke, Marie Luise, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Schneider, Udo, Kawelke, Leona, Ruffer, Nikolas, Stenzel, Werner, Krönke, Gerhard, Simon, David
ORCID: https://orcid.org/0000-0001-8310-7820 and Alexander, Tobias
Annals of the Rheumatic Diseases 85
(1): 212-215.
January 2026
Recombination junctions from antibody isotype switching classify immune and DNA repair dysfunction.
Vázquez García, Clara
ORCID: https://orcid.org/0000-0003-4583-7616, Obermayer, Benedikt
ORCID: https://orcid.org/0000-0002-9116-630X, Keller, Baerbel, Lebedin, Mikhail
ORCID: https://orcid.org/0000-0002-3877-7195, Ratswohl, Christoph
ORCID: https://orcid.org/0000-0001-5413-0730, Abolhassani, Hassan
ORCID: https://orcid.org/0000-0002-4838-0407, Busse, Antonia
ORCID: https://orcid.org/0000-0002-3470-6947, Di Virgilio, Michela
ORCID: https://orcid.org/0000-0001-5189-0793, Mathas, Stephan
ORCID: https://orcid.org/0000-0001-9626-1413, Speiser, Dorothee, Beule, Dieter
ORCID: https://orcid.org/0000-0002-3284-0632, Pan-Hammarström, Qiang
ORCID: https://orcid.org/0000-0003-1990-8804, Warnatz, Klaus
ORCID: https://orcid.org/0000-0002-1172-865X and de la Rosa, Kathrin
ORCID: https://orcid.org/0000-0003-4809-3157
Nature Communications 16
(1): 11331.
19 December 2025
Clinical and echocardiographic phenotype of cardiac wasting in patients with advanced cancer.
Anker, Markus S.
ORCID: https://orcid.org/0000-0002-4406-8555, Khan, Muhammad Shahzeb, Nikolski, Anja, Porthun, Jan, Arshad, Muhammad Sameer, Hadzibegovic, Sara, Lena, Alessia, Kretzler, Lucie, Hella, Jonathan L., Witkowski, Marco, Rieger, Kathrin, Ahn, Johann, Modest, Dominik P., Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, Lars
ORCID: https://orcid.org/0000-0002-5890-5510, Totzeck, Matthias, Mahabadi, Amir A., Rassaf, Tienush, Buchmann, Nikolaus, Attanasio, Philipp, Zeller, Tanja, Karakas, Mahir, Tocchetti, Carlo G., Wilkenshoff, Ursula, Cleland, John G.F., von Haehling, Stephan, Butler, Javed and Landmesser, Ulf
European Journal of Heart Failure 27
(11): 2130-2140.
November 2025
Chronic inflammatory demyelinating polyneuropathy (CIDP) after cilta-cel therapy.
Korenkov, M.
ORCID: https://orcid.org/0000-0002-2988-8483, Liebaert, J.
ORCID: https://orcid.org/0000-0002-2988-8483, Yousefian, S.
ORCID: https://orcid.org/0000-0003-0902-0369, Schwartz, S.
ORCID: https://orcid.org/0000-0001-8833-5793, Demel, U.M.
ORCID: https://orcid.org/0000-0002-6480-4185, Braune, J.
ORCID: https://orcid.org/0000-0003-2026-2641, Odabasi, M.C., Herzberg, L., Böckle, D., Görür, N.C.
ORCID: https://orcid.org/0000-0001-7857-2461, V. Landenberg-Roberg, V., Bohl, S., Tregel, E., Hennig, S., Franke, C.
ORCID: https://orcid.org/0000-0002-5609-2472, Haas, S.
ORCID: https://orcid.org/0000-0001-9227-2051, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Krönke, J. and Busse, A.
ORCID: https://orcid.org/0000-0002-3470-6947
Blood Cancer Journal 15
(1): 168.
20 October 2025
Randomized investigation of heart failure therapy in patients with advanced cancer at risk of cardiac wasting: rationale and design of the EMPATICC trial.
Anker, Markus S.
ORCID: https://orcid.org/0000-0002-4406-8555, Mahabadi, Amir A., Totzeck, Matthias, Tewes, Mitra, Mincu, Raluca, Khan, Muhammad Shahzeb, Butler, Javed, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Ahn, Johann, Bullinger, Lars
ORCID: https://orcid.org/0000-0002-5890-5510, Modest, Dominik P., Landmesser, Ulf, Lehmann, Lorenz H., Bercker, Sven, Laufs, Ulrich, Böhm, Michael, Merkely, Bela, Diek, Monika, Heise, Tim, Hellmich, Martin, Placzek, Marius, Friede, Tim
ORCID: https://orcid.org/0000-0001-5347-7441, Anker, Stefan D. and Rassaf, Tienush
European Journal of Heart Failure 27
(10): 1905-1917.
October 2025
Ultra-high-scale cytometry-based cellular interaction mapping.
Vonficht, Dominik
ORCID: https://orcid.org/0000-0002-5579-7083, Jopp-Saile, Lea
ORCID: https://orcid.org/0000-0002-7032-3003, Yousefian, Schayan
ORCID: https://orcid.org/0000-0003-0902-0369, Flore, Viktoria
ORCID: https://orcid.org/0009-0001-3023-433X, Simó Vesperinas, Inés, Teuber, Ruth, Avanesyan, Bogdan
ORCID: https://orcid.org/0009-0004-2547-6598, Luo, Yanjiang
ORCID: https://orcid.org/0009-0003-0401-467X, Röthemeier, Caroline, Grünschläger, Florian
ORCID: https://orcid.org/0000-0003-0021-6912, Fernandez-Vaquero, Mirian, Fregona, Vincent
ORCID: https://orcid.org/0000-0003-4857-1737, Ordoñez-Rueda, Diana
ORCID: https://orcid.org/0000-0002-8387-6707, Schmalbrock, Laura K.
ORCID: https://orcid.org/0000-0002-6080-6175, Deininger, Luca
ORCID: https://orcid.org/0009-0005-5125-6422, Yamachui Sitcheu, Angelo Jovin
ORCID: https://orcid.org/0009-0002-9384-6496, Gu, Zuguang, Funk, Maja C.
ORCID: https://orcid.org/0000-0002-6007-1164, Mikut, Ralf
ORCID: https://orcid.org/0000-0001-9100-5496, Heikenwälder, Mathias, Eggert, Angelika, von Stackelberg, Arend, Kobold, Sebastian
ORCID: https://orcid.org/0000-0002-5612-4673, Krönke, Jan, Keller, Ulrich
ORCID: https://orcid.org/0000-0002-8485-1958, Trumpp, Andreas, Hegazy, Ahmed N., Eckert, Cornelia
ORCID: https://orcid.org/0000-0003-1039-2872, Hübschmann, Daniel
ORCID: https://orcid.org/0000-0002-6041-7049 and Haas, Simon
ORCID: https://orcid.org/0000-0001-9227-2051
Nature Methods 22
(9): 1887-1899.
September 2025
A macrophage-predominant immunosuppressive microenvironment and therapeutic vulnerabilities in advanced salivary gland cancer.
Zuljan, E., von der Emde, B., Piwonski, I., Pestana, A., Klinghammer, K.
ORCID: https://orcid.org/0000-0001-6425-4833, Mock, A.
ORCID: https://orcid.org/0000-0002-3332-9166, Horak, P.
ORCID: https://orcid.org/0000-0003-4536-9306, Heining, C., Klauschen, F.
ORCID: https://orcid.org/0000-0002-9131-2389, Pretzell, I., Boerries, M.
ORCID: https://orcid.org/0000-0002-3670-0602, Brandts, C.H., Kreutzfeldt, S.
ORCID: https://orcid.org/0000-0003-3278-4586, Teleanu, M.V., Hübschmann, D.
ORCID: https://orcid.org/0000-0002-6041-7049, Morris, L.G.T.
ORCID: https://orcid.org/0000-0002-4417-2280, Heiland, M.
ORCID: https://orcid.org/0000-0002-4987-2913, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Conrad, T.
ORCID: https://orcid.org/0000-0001-5618-6295, Glimm, H.
ORCID: https://orcid.org/0000-0003-4104-1135, Fröhling, S.
ORCID: https://orcid.org/0000-0001-7907-4595, Ochsenreither, S.
ORCID: https://orcid.org/0000-0001-6024-4312, Keilholz, U., Blanc, E.
ORCID: https://orcid.org/0000-0002-4369-0254, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632 and Rieke, D.T.
ORCID: https://orcid.org/0000-0003-0027-7977
Nature Communications 16
(1): 5303.
12 June 2025
New cardiovascular biomarkers in patients with advanced cancer – a prospective study comparing MR-proADM, MR-proANP, copeptin, high-sensitivity troponin T and NT-proBNP.
Anker, M.S.
ORCID: https://orcid.org/0000-0002-4406-8555, Lück, L.C., Khan, M.S., Porthun, J., Hadzibegovic, S., Lena, A., Wilkenshoff, U., Weinländer, P., Evertz, R., Totzeck, M., Mahabadi, A.A., Rassaf, T., Anker, S.D.
ORCID: https://orcid.org/0000-0002-4406-8555, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Karakas, M., Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 27
(6): 1047-1055.
June 2025
Guiding clinical management of patients with CNS lymphomas by minimal-invasive detection of ctDNA in cerebrospinal fluid.
Weinschenk, S, Philipp, U, Kuehn, J C, Mueller, K, Fauser, J, Boeckle, D, Gebhard, I, Hinz, M, Neidert, N, Bleul, S, Lauer, E M, Mutter, J A, Alig, S K, Kurtz, D M, Finke, J, Marks, R, Diehn, M, Alizadeh, A A, Reinacher, P C, Wehrle, J, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Wolf, D, Kocher, F, Chapuy, B, Beck, J, Prinz, M, von Baumgarten, L, Schorb, E, Duyster, J and Scherer, F
Leukemia 39
(5): 1265-1268.
May 2025
Teclistamab in relapsed systemic sclerosis after autologous haematopoietic stem cell transplantation.
Siegert, E., Biesen, R.
ORCID: https://orcid.org/0000-0002-0434-7832, Dzamukova, M.
ORCID: https://orcid.org/0000-0002-2389-3222, Furth, C., Probst, M.
ORCID: https://orcid.org/0009-0004-3390-6789, Doellinger, F.
ORCID: https://orcid.org/0000-0003-3661-8569, Walter-Rittel, T., Fleischmann, A., Wilhelm, A., Beenken, A.E., Wiebe, E., Pecher, A.C.
ORCID: https://orcid.org/0000-0003-0201-0686, Henes, J.
ORCID: https://orcid.org/0000-0002-8385-6861, Florian, S., Simon, D., Kleyer, A., Burmester, G.R., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Krönke, J., Krönke, G. and Alexander, T.
ORCID: https://orcid.org/0000-0003-1193-0097
Annals of the Rheumatic Diseases 84
(4): 653-656.
April 2025
Segment anything for microscopy.
Archit, A.
ORCID: https://orcid.org/0009-0002-9533-8620, Freckmann, L., Nair, S., Khalid, N.
ORCID: https://orcid.org/0000-0001-9274-3757, Hilt, P., Rajashekar, V., Freitag, M.
ORCID: https://orcid.org/0009-0005-0920-2535, Teuber, C.
ORCID: https://orcid.org/0009-0004-3866-191X, Spitzner, M., Tapia Contreras, C., Buckley, G.
ORCID: https://orcid.org/0000-0003-2763-492X, von Haaren, S., Gupta, S., Grade, M., Wirth, M.
ORCID: https://orcid.org/0000-0002-8340-0872, Schneider, G., Dengel, A., Ahmed, S. and Pape, C.
ORCID: https://orcid.org/0000-0001-6562-7187
Nature Methods 22
(3): 579-591.
March 2025
Growth differentiation factor-15: a promising biomarker and target in cancer patients.
Anker, M., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958 and Khan, M.S.
JACC: CardioOncology 7
(2): 153-156.
February 2025
Therapy-related AML: long-term outcome in a large cohort of AML-patients with intensive and non-intensive therapy.
Gross, S., Ihlow, J.
ORCID: https://orcid.org/0000-0001-5484-1321, Busack, L., Adamiak, K., Schrezenmeier, J., Jesse, J., Schwarz, M., Flörcken, A., Vuong, L.G., Rieger, K., Krönke, J.
ORCID: https://orcid.org/0000-0002-4649-0506, le Coutre, P., Boldt, V., von Brünneck, A.C., Horst, D., Burmeister, T.
ORCID: https://orcid.org/0000-0003-4843-2876, Blau, I.W., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510 and Westermann, J.
Blood Cancer Journal 14
(1): 160.
16 September 2024
Teclistamab-induced remission in refractory systemic lupus erythematosus.
Alexander, T.
ORCID: https://orcid.org/0000-0003-1193-0097, Krönke, J., Cheng, Q., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958 and Krönke, G.
New England Journal of Medicine 391
(9): 864-866.
5 September 2024
The proteogenomic landscape of multiple myeloma reveals insights into disease biology and therapeutic opportunities.
Ramberger, E.
ORCID: https://orcid.org/0000-0003-2760-2696, Sapozhnikova, V., Ng, Y.L.D., Dolnik, A., Ziehm, M.
ORCID: https://orcid.org/0000-0001-7074-4054, Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Sträng, E., Kull, M., Grünschläger, F.
ORCID: https://orcid.org/0000-0003-0021-6912, Krüger, J.
ORCID: https://orcid.org/0000-0001-5789-4082, Benary, M.
ORCID: https://orcid.org/0000-0002-3067-2030, Müller, S.
ORCID: https://orcid.org/0009-0003-6363-5599, Gao, X., Murgai, A.
ORCID: https://orcid.org/0000-0001-9767-7402, Haji, M., Schmidt, A., Lutz, R., Nogai, A., Braune, J.
ORCID: https://orcid.org/0000-0003-2026-2641, Laue, D.
ORCID: https://orcid.org/0000-0002-7237-9414, Langer, C., Khandanpour, C., Bassermann, F.
ORCID: https://orcid.org/0000-0003-4435-2609, Döhner, H.
ORCID: https://orcid.org/0000-0003-2116-5536, Engelhardt, M.
ORCID: https://orcid.org/0000-0003-0405-1676, Straka, C., Hundemer, M.
ORCID: https://orcid.org/0000-0002-5596-2405, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Haas, S.
ORCID: https://orcid.org/0000-0001-9227-2051, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Einsele, H.
ORCID: https://orcid.org/0000-0002-7680-0819, Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Knop, S.
ORCID: https://orcid.org/0000-0003-1276-6639, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X and Krönke, J.
Nature Cancer 5
(8): 1267-1284.
August 2024
A hypoxia-epigenetics axis drives EMT in pancreatic cancer.
Wirth, M.
ORCID: https://orcid.org/0000-0002-8340-0872 and Schneider, G.
ORCID: https://orcid.org/0000-0003-1840-4508
Cancer Research 84
(11): 1739-1741.
1 June 2024
Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022.
Baumgartner, F.
ORCID: https://orcid.org/0000-0003-0768-1956, Baer, C., Bamopoulos, S.A.
ORCID: https://orcid.org/0000-0002-5997-7735, Ayoub, E.
ORCID: https://orcid.org/0000-0003-1321-0114, Truger, M., Meggendorfer, M., Lenk, M., Hoermann, G., Hutter, S.
ORCID: https://orcid.org/0000-0003-2432-8898, Müller, H., Walter, W.
ORCID: https://orcid.org/0000-0002-5083-9838, Mueller, M.L., Nadarajah, Ni., Blombery, P., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Kern, W., Haferlach, C. and Haferlach, T.
Blood 143
(12): 1139-1156.
21 March 2024
Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Dönig, J., Mende, H., Davila Gallesio, J., Wagner, K., Hotz, P.
ORCID: https://orcid.org/0000-0002-3710-6840, Schunck, K., Piller, T.
ORCID: https://orcid.org/0000-0001-8545-2089, Hölper, S., Uhan, S., Kaulich, M.
ORCID: https://orcid.org/0000-0002-9528-8822, Wirth, M.
ORCID: https://orcid.org/0000-0002-8340-0872, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Tascher, G.
ORCID: https://orcid.org/0000-0002-5907-3947, Bohnsack, K.E.
ORCID: https://orcid.org/0000-0001-6035-4255 and Müller, S.
ORCID: https://orcid.org/0000-0002-8792-7700
Nature Communications 14
(1): 8121.
8 December 2023
Leveraging large language models for decision support in personalized oncology.
Benary, M.
ORCID: https://orcid.org/0000-0002-3067-2030, Wang, X.D., Schmidt, M., Soll, D., Hilfenhaus, G.
ORCID: https://orcid.org/0000-0001-8764-077X, Nassir, M., Sigler, C., Knödler, M., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Keilholz, U., Leser, U. and Rieke, D.T.
JAMA Network Open 6
(11): e2343689.
November 2023
Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire.
Anker, M.S., Potthoff, S.K., Lena, A., Porthun, J., Hadzibegovic, S., Evertz, R., Denecke, C., Fröhlich, A.K., Sonntag, F., Regitz-Zagrosek, V., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Spertus, J.A., Anker, S.D., Karakas, M., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 25
(9): 1635-1647.
September 2023
Clinical and prognostic relevance of cardiac wasting in patients with advanced cancer.
Lena, A., Wilkenshoff, U., Hadzibegovic, S., Porthun, J., Rösnick, L., Fröhlich, A.K., Zeller, T., Karakas, M., Keller, U.
ORCID: https://orcid.org/0000-0002-8485-1958, Ahn, J., Bullinger, L.
ORCID: https://orcid.org/0000-0002-5890-5510, Riess, H., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Totzeck, M., Rassaf, T., Burkhoff, D., Mehra, M.R., Bax, J.J., Butler, J., Edelmann, F., Haverkamp, W., Anker, S.D., Packer, M., Coats, A.J.S., von Haehling, S., Landmesser, U. and Anker, M.S.
Journal of the American College of Cardiology 81
(16): 1569-1586.
25 April 2023
The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
Paulmann, C., Spallek, R., Karpiuk, O., Heider, M., Schäffer, I., Zecha, J.
ORCID: https://orcid.org/0000-0002-8767-6294, Klaeger, S., Walzik, M., Öllinger, R.
ORCID: https://orcid.org/0000-0002-2292-5982, Engleitner, T., Wirth, M.
ORCID: https://orcid.org/0000-0002-8340-0872, Keller, U.
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Trends in Neurosciences 42
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Acta Neuropathologica 135
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Szulzewsky, F.
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Neuro-Oncology 20
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S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.
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Neuron 96
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Microglia in physiology and disease.
Wolf, S.A.
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Annual Review of Physiology 79
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The role of microglia and macrophages in glioma maintenance and progression.
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Nature Neuroscience 19
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January 2016
Vascular signal transducer and activator of transcription-3 promotes angiogenesis and neuroplasticity long-term after stroke.
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Microglia: new roles for the synaptic stripper.
Kettenmann, H.
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Nature Medicine 18
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Physiological Reviews 91
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Trends in Neurosciences 31
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Association of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure.
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Hepatology 46
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Microglia: active sensor and versatile effector cells in the normal and pathologic brain.
Hanisch, U.K. and Kettenmann, H.
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Nature Neuroscience 10
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November 2007
Neurotransmitter receptors on microglia.
Pocock, J.M. and Kettenmann, H.
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Trends in Neurosciences 30
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October 2007
Neuroscience: The brain's garbage men.
Kettenmann, H.
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Nature 446
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Nature Neuroscience 9
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Neuronal or glial progeny: Regional differences in radial glia fate.
Malatesta, P., Hack, M.A., Hartfuss, E., Kettenmann, H.
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Neuron 37
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6 March 2003
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Schipke, C.G.
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1 December 2001
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Trends in Neurosciences 22
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1 July 1999
Glial calcium: Homeostasis and signaling function.
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Physiological Reviews 78
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January 1998
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1 January 1997
Na+/Ca2+ exchanger modulates kainate- triggered Ca2+ signaling in Bergmann glial cells in situ.
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FASEB Journal 11
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1 January 1997
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Verkhratsky, A. and Kettenmann, H.
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Trends in Neurosciences 19
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1 August 1996
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CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
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Annals of the Rheumatic Diseases 81
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Neutrophil gelatinase-associated lipocalin protects from ANCA-induced GN by inhibiting T(H)17 immunity.
Schreiber, A.
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Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets.
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Plasma exchange for primary autoimmune autonomic failure.
Schroeder, C., Vernino, S., Birkenfeld, A.L., Tank, J., Heusser, K., Lipp, A., Benter, T., Lindschau, C.
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ORCID: https://orcid.org/0000-0001-7468-9531, Marko, L.
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ORCID: https://orcid.org/0000-0002-5152-5830, Chen, C.Y.
ORCID: https://orcid.org/0000-0003-1765-7132, N'Diaye, G., Löber, U.
ORCID: https://orcid.org/0000-0001-7468-9531, Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Fritsche-Guenther, R.
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ORCID: https://orcid.org/0000-0002-7219-6896, Yarritu, A.
ORCID: https://orcid.org/0000-0002-1724-0559, Zhong, C., Fei, L., Tsvetkov, D.
ORCID: https://orcid.org/0000-0002-6472-971X, Todiras, M.
ORCID: https://orcid.org/0000-0002-9373-4753, Park, J.K., Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Maifeld, A.
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ORCID: https://orcid.org/0000-0003-4780-4164, Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299, Kirwan, J.A.
ORCID: https://orcid.org/0000-0002-5423-1651, Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644 and Wilck, N.
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Cardiovascular Research 119
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Inflammation in children with chronic kidney disease linked to gut dysbiosis and metabolite imbalance.
Holle, J.
ORCID: https://orcid.org/0000-0001-8032-4096, Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Löber, U.
ORCID: https://orcid.org/0000-0001-7468-9531, Behrens, F.
ORCID: https://orcid.org/0000-0002-6841-4192, Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Anandakumar, H.
ORCID: https://orcid.org/0009-0000-3326-5126, Wimmer, M., Vu, D.L., Kuhring, M.
ORCID: https://orcid.org/0000-0002-3287-0313, Brüning, U.
ORCID: https://orcid.org/0000-0003-0112-4032, Maifeld, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Geisberger, S.
ORCID: https://orcid.org/0000-0001-6477-1312, Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299, Schumacher, F., Kleuser, B., Bufler, P., Querfeld, U., Kitschke, S., Engler, D., Kuhrt, L.D.
ORCID: https://orcid.org/0000-0001-7157-6988, Drechsel, O., Eckardt, K.U., Forslund, S.
ORCID: https://orcid.org/0000-0003-4285-6993, Thürmer, A., McParland, V.
ORCID: https://orcid.org/0000-0003-0731-3272, Kirwan, J.
ORCID: https://orcid.org/0000-0002-5423-1651, Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364 and Mueller, D.
Journal of the American Society of Nephrology 33
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December 2022
MetExplore: collaborative edition and exploration of metabolic networks.
Cottret, L.
ORCID: https://orcid.org/0000-0001-7418-7750, Frainay, C., Chazalviel, M., Cabanettes, F., Gloaguen, Y.
ORCID: https://orcid.org/0000-0003-0493-8592, Camenen, E., Merlet, B., Heux, S., Portais, J.C., Poupin, N., Vinson, F. and Jourdan, F.
Nucleic Acids Research 46
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2 July 2018
Klaassen, Sabine (ECRC)
DNA methylation analysis of NOTCH1 variants reveals the first episignature for non-syndromic congenital heart defects.
Dombrowsky, Gregor
ORCID: https://orcid.org/0000-0003-2591-2682, van der Laan, Liselot
ORCID: https://orcid.org/0000-0002-7800-8665, Silva, Ananília
ORCID: https://orcid.org/0000-0002-4730-9676, Breckpot, Jeroen
ORCID: https://orcid.org/0000-0002-0734-5154, Audain, Enrique
ORCID: https://orcid.org/0000-0002-9201-7840, Wilsdon, Anna, Levy, Michael A., Vos, Niels
ORCID: https://orcid.org/0000-0001-6001-3426, Mannens, Marcel
ORCID: https://orcid.org/0000-0001-7137-119X, Wang, Jiao, Jain, Anjali, Lesurf, Robert
ORCID: https://orcid.org/0000-0001-7095-1491, Winlaw, David
ORCID: https://orcid.org/0000-0001-8005-3361, Bezzina, Connie R.
ORCID: https://orcid.org/0000-0002-0633-3514, Thomas, Mary Ann
ORCID: https://orcid.org/0009-0006-8855-7445, Caliebe, Almuth
ORCID: https://orcid.org/0000-0003-2157-425X, Klaassen, Sabine
ORCID: https://orcid.org/0000-0001-5925-9912, Berger, Felix
ORCID: https://orcid.org/0000-0001-7881-1557, Dittrich, Sven
ORCID: https://orcid.org/0000-0002-8455-3416, Stiller, Brigitte
ORCID: https://orcid.org/0000-0002-7657-4647, Abdul-Khaliq, Hashim, Dähnert, Ingo, Bu'Lock, Frances, Loughna, Siobhan
ORCID: https://orcid.org/0000-0002-3277-1438, Brook, J. David
ORCID: https://orcid.org/0000-0002-5946-6740, Mital, Seema
ORCID: https://orcid.org/0000-0002-7643-4484, Russell, Robert B.
ORCID: https://orcid.org/0000-0002-1905-4717, Pickardt, Thomas, Bauer, Ulrike, Kramer, Hans-Heiner, Uebing, Anselm
ORCID: https://orcid.org/0000-0001-8504-0228, Henneman, Peter
ORCID: https://orcid.org/0000-0003-2179-7808, Sadikovic, Bekim
ORCID: https://orcid.org/0000-0001-6363-0016, Postma, Alex
ORCID: https://orcid.org/0000-0003-4874-2487 and Hitz, Marc-Phillip
ORCID: https://orcid.org/0000-0001-9894-6897
Genome Medicine 18
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7 January 2026
Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch, J.
ORCID: https://orcid.org/0000-0003-4744-5421, Theisen, S., Dartsch, J.
ORCID: https://orcid.org/0000-0002-7947-2881, Fritsche-Guenther, R.
ORCID: https://orcid.org/0000-0002-6965-0226, Kirchner, M.
ORCID: https://orcid.org/0000-0002-7049-534X, Obermayer, B.
ORCID: https://orcid.org/0000-0002-9116-630X, Bauer, A., Kahlert, A.K., Rothe, M.
ORCID: https://orcid.org/0000-0002-6813-4705, Beule, D.
ORCID: https://orcid.org/0000-0002-3284-0632, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Kirwan, J.A.
ORCID: https://orcid.org/0000-0002-5423-1651, Berndt, N., MacRae, C.A., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Klaassen, S.
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Cardiovascular Research 119
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December 2023
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.
Arndt, A.K., Schaefer, S., Drenckhahn, J.D.
ORCID: https://orcid.org/0000-0001-8347-7696, Sabeh, M.K., Plovie, E.R., Caliebe, A., Klopocki, E., Musso, G., Werdich, A.A., Kalwa, H., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Padera, R.F., Wassilew, K., Bluhm, J., Harnack, C., Martitz, J., Barton, P.J., Greutmann, M., Berger, F., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Siebert, R., Kramer, H.H., Cook, S.A., Macrae, C.A. and Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912
American Journal of Human Genetics 93
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11 July 2013
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.
Guo, W., Schafer, S., Greaser, M.L., Radke, M.H.
ORCID: https://orcid.org/0000-0003-0112-9917, Liss, M.
ORCID: https://orcid.org/0000-0002-0585-7850, Govindarajan, T., Maatz, H.
ORCID: https://orcid.org/0000-0002-9232-6272, Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Lincoln, S.E., Parrish, A.M., Dauksaite, V.
ORCID: https://orcid.org/0000-0002-9399-4731, Vakeel, P., Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Thierfelder, L., Regitz-Zagrosek, V., Hacker, T.A., Saupe, K.W., Dec, G.W., Ellinor, P.T., MacRae, C.A., Spallek, B., Fischer, R.
ORCID: https://orcid.org/0000-0002-4828-2882, Perrot, A.
ORCID: https://orcid.org/0000-0002-8800-342X, Ozcelik, C., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Gotthardt, M.
ORCID: https://orcid.org/0000-0003-1788-3172
Nature Medicine 18
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May 2012
Mutations in sarcomere protein genes in left ventricular noncompaction.
Klaassen, S., Probst, S., Oechslin, E., Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Krings, G., Schuler, P., Greutmann, M., Huerlimann, D., Yegitbasi, M., Pons, L., Gramlich, M., Drenckhahn, J.D.
ORCID: https://orcid.org/0000-0001-8347-7696, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Berger, F., Jenni, R. and Thierfelder, L.
Circulation 117
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3 June 2008
Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy.
Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Plovie, E.R., Ellinor, P.T., Grossmann, K.S., Shin, J.T., Wichter, T., Basson, C.T., Lerman, B.B., Sasse-Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Thierfelder, L., MacRae, C.A. and Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826
American Journal of Human Genetics 79
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December 2006
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Wichter, T., Paul, M., Basson, C.T., McDermott, D.A., Lerman, B.B., Markowitz, S.M., Ellinor, P.T., MacRae, C.A., Peters, S., Grossmann, K.S., Drenckhahn, J.
ORCID: https://orcid.org/0000-0001-8347-7696, Michely, B., Sasse-Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Birchmeier, W.
ORCID: https://orcid.org/0000-0003-1173-0829, Dietz, R., Breithardt, G., Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36
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November 2004
Novel gene locus for autosomal dominant left ventricular noncompaction maps to chromosome 11p15.
Sasse-Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Probst, S., Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Oechslin, E., Nuernberg, P., Heuser, A., Jenni, R., Hennies, H.C.
ORCID: https://orcid.org/0000-0001-7210-2389 and Thierfelder, L.
Circulation 109
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8 June 2004
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.
Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Gramlich, M., Atherton, J., McNabb, M., Trombitas, K., Sasse-Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Seidman, J.G., Seidman, C., Granzier, H.
ORCID: https://orcid.org/0000-0002-9516-407X, Labeit, S., Frenneaux, M. and Thierfelder, L.
Nature Genetics 30
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February 2002
Klussmann, Enno
AKAP signaling: physiological and pathophysiological role and opportunities for novel therapeutic concepts.
Herberg, Friedrich W., Paolocci, Ester and Klussmann, Enno
ORCID: https://orcid.org/0000-0003-4004-5003
Physiological Reviews
19 May 2026
(In Press)
Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels.
Handklo-Jamal, Reem
ORCID: https://orcid.org/0000-0001-6237-5412, Raifman, Tal Keren, Shalomov, Boris
ORCID: https://orcid.org/0000-0002-1322-4906, Hofer, Patrick
ORCID: https://orcid.org/0009-0004-5778-9599, Kahanovitch, Uri, Friesacher, Theres
ORCID: https://orcid.org/0000-0001-5632-3472, Tabak, Galit, Tsemakhovich, Vladimir, Reddy, Haritha P., Chomsky-Hecht, Orna, Tripathy, Debi Ranjan, Zuhlke, Kerstin, Dessauer, Carmen W., Klussmann, Enno
ORCID: https://orcid.org/0000-0003-4004-5003, Haitin, Yoni
ORCID: https://orcid.org/0000-0002-1648-6792, Hirsch, Joel A.
ORCID: https://orcid.org/0000-0001-7544-8668, Stary-Weinzinger, Anna
ORCID: https://orcid.org/0000-0002-9202-0484, Yakubovich, Daniel
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Nature Communications 16
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29 December 2025
Activated CaMKIIδ translocates to the RyR nanodomain in cardiomyocytes.
Bergan-Dahl, Anna
ORCID: https://orcid.org/0000-0003-1145-596X, Carlson, Cathrine R., Laasmaa, Martin, Subramanian, Hariharan, Basson, Adelle, Li, Jia, Hasic, Almira, Lunde, Marianne, Ugland, Hege, Manfra, Ornella
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ORCID: https://orcid.org/0000-0003-4004-5003, Bossuyt, Julie, Bers, Donald M.
ORCID: https://orcid.org/0000-0002-2237-9483, Nikolaev, Viacheslav O., Louch, William E.
ORCID: https://orcid.org/0000-0002-0511-6112 and Shen, Xin
Cardiovascular Research 121
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October 2025
Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A.
ORCID: https://orcid.org/0000-0002-1263-2078, Walter, S., Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, McMurray, B.J., Sunaga-Franze, D.Y.
ORCID: https://orcid.org/0000-0002-6851-9162, Xu, M., Zühlke, K., Russwurm, M., Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Langanki, R., Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Patzak, A., Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Borodina, T.
ORCID: https://orcid.org/0000-0002-6978-016X, Persson, P.B., Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164 and Klussmann, E.
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Kidney International 104
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Integrated proteomics unveils nuclear PDE3A2 as a regulator of cardiac myocyte hypertrophy.
Subramaniam, G., Schleicher, K., Kovanich, D.
ORCID: https://orcid.org/0000-0001-5974-829X, Zerio, A., Folkmanaite, M.
ORCID: https://orcid.org/0000-0003-0469-8787, Chao, Y.C.
ORCID: https://orcid.org/0000-0001-5946-6196, Surdo, N.C., Koschinski, A., Hu, J.
ORCID: https://orcid.org/0000-0003-1384-7465, Scholten, A., Heck, A.J.R
ORCID: https://orcid.org/0000-0002-2405-4404, Ercu, M., Sholokh, A.
ORCID: https://orcid.org/0000-0002-1263-2078, Chan Park, K.
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Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single cell transcriptomics.
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ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M.
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Cell 185
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Cell 184
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Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression.
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ORCID: https://orcid.org/0000-0002-3292-6671, Wyler, E.
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16 November 2021
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Nature 599
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11 November 2021
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Immunity 54
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9 November 2021
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7 October 2021
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ORCID: https://orcid.org/0000-0003-1973-3119, Wyler, E.
ORCID: https://orcid.org/0000-0002-9884-1806, Pennitz, P.
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Nature Communications 12
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11 August 2021
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
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Nature Communications 12
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21 June 2021
Swarm Learning for decentralized and confidential clinical machine learning.
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Nature 594
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10 June 2021
Spatio-temporal mRNA tracking in the early zebrafish embryo.
Holler, K.
ORCID: https://orcid.org/0000-0002-5159-9223, Neuschulz, A.
ORCID: https://orcid.org/0000-0001-6163-3344, Drewe-Boß, P.
ORCID: https://orcid.org/0000-0002-5459-9771, Mintcheva, J.
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Nature Communications 12
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7 June 2021
DDX3 depletion represses translation of mRNAs with complex 5' UTRs.
Calviello, L.
ORCID: https://orcid.org/0000-0002-5600-0988, Venkataramanan, S.
ORCID: https://orcid.org/0000-0002-2507-401X, Rogowski, K.J.
ORCID: https://orcid.org/0000-0002-9634-7353, Wyler, E.
ORCID: https://orcid.org/0000-0002-9884-1806, Wilkins, K., Tejura, M., Thai, B., Krol, J., Filipowicz, W., Landthaler, M.
ORCID: https://orcid.org/0000-0002-1075-8734 and Floor, S.N.
ORCID: https://orcid.org/0000-0002-9965-9694
Nucleic Acids Research 49
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May 2021
Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
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ORCID: https://orcid.org/0000-0002-0402-8647, Harnett, D.
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ORCID: https://orcid.org/0000-0002-0782-7751, Vieira-Vieira, C.H.
ORCID: https://orcid.org/0000-0001-5443-4507, Schaub, T.
ORCID: https://orcid.org/0000-0003-0790-5040, Münster-Wandowski, A., Bürger, J., Borisova, E., Yamamoto, H., Rasin, M.R., Ohler, U.
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Molecular Cell 81
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21 January 2021
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
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Genome Medicine 13
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13 January 2021
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19.
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Immunity 53
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15 December 2020
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Cell 182
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17 September 2020
Integrative functional genomics decodes herpes simplex virus 1.
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20 February 2026
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Iakupova, Alisa
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ORCID: https://orcid.org/0000-0002-1218-6223 and Seidman, C.E.
ORCID: https://orcid.org/0000-0001-6380-1209
Science 377
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5 August 2022
Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.
Grosche, S.
ORCID: https://orcid.org/0000-0002-7658-0932, Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Esparza-Gordillo, J., Arnau-Soler, A.
ORCID: https://orcid.org/0000-0001-9768-0513, Pairo-Castineira, E.
ORCID: https://orcid.org/0000-0002-2423-3090, Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Ahluwalia, T.S.
ORCID: https://orcid.org/0000-0002-7464-3354, Almqvist, C., Arnold, A., Baurecht, H.
ORCID: https://orcid.org/0000-0002-9265-5594, Bisgaard, H.
ORCID: https://orcid.org/0000-0003-4131-7592, Bønnelykke, K.
ORCID: https://orcid.org/0000-0003-2003-1018, Brown, S.J.
ORCID: https://orcid.org/0000-0002-3232-5251, Bustamante, M.
ORCID: https://orcid.org/0000-0003-0127-2860, Curtin, J.A., Custovic, A.
ORCID: https://orcid.org/0000-0001-5218-7071, Dharmage, S.C., Esplugues, A., Falchi, M.
ORCID: https://orcid.org/0000-0002-5646-1004, Fernandez-Orth, D.
ORCID: https://orcid.org/0000-0002-1237-3192, Ferreira, M.A.R., Franke, A.
ORCID: https://orcid.org/0000-0003-1530-5811, Gerdes, S., Gieger, C.
ORCID: https://orcid.org/0000-0001-6986-9554, Hakonarson, H.
ORCID: https://orcid.org/0000-0003-2814-7461, Holt, P.G.
ORCID: https://orcid.org/0000-0003-1193-0935, Homuth, G., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Hysi, P.G.
ORCID: https://orcid.org/0000-0001-5752-2510, Jarvelin, M.R.
ORCID: https://orcid.org/0000-0002-2149-0630, Karlsson, R.
ORCID: https://orcid.org/0000-0002-8949-2587, Koppelman, G.H.
ORCID: https://orcid.org/0000-0001-8567-3252, Lau, S., Lutz, M., Magnusson, P.K.E.
ORCID: https://orcid.org/0000-0002-7315-7899, Marks, G.B., Müller-Nurasyid, M.
ORCID: https://orcid.org/0000-0003-3793-5910, Nöthen, M.M.
ORCID: https://orcid.org/0000-0002-8770-2464, Paternoster, L.
ORCID: https://orcid.org/0000-0003-2514-0889, Pennell, C.E.
ORCID: https://orcid.org/0000-0002-0937-6165, Peters, A.
ORCID: https://orcid.org/0000-0001-6645-0985, Rawlik, K.
ORCID: https://orcid.org/0000-0002-0010-370X, Robertson, C.F., Rodriguez, E.
ORCID: https://orcid.org/0000-0003-3692-3950, Sebert, S.
ORCID: https://orcid.org/0000-0001-6681-6983, Simpson, A., Sleiman, P.M.A., Standl, M., Stölzl, D., Strauch, K., Szwajda, A., Tenesa, A.
ORCID: https://orcid.org/0000-0003-4884-4475, Thompson, P.J., Ullemar, V., Visconti, A.
ORCID: https://orcid.org/0000-0003-4144-2019, Vonk, J.M.
ORCID: https://orcid.org/0000-0001-7531-4547, Wang, C.A.
ORCID: https://orcid.org/0000-0002-4301-3974, Weidinger, S., Wielscher, M., Sargent, C.L.
ORCID: https://orcid.org/0000-0002-1796-9606, Xu, C.J. and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
Nature Communications 12
(1): 6618.
16 November 2021
Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis.
Thyssen, J.P.
ORCID: https://orcid.org/0000-0003-3770-1743, Ahluwalia, T.S.
ORCID: https://orcid.org/0000-0002-7464-3354, Paternoster, L., Ballardini, N.
ORCID: https://orcid.org/0000-0001-6759-346X, Bergström, A., Melén, E., Chawes, B., Stokholm, J., Hourihane, J.O., O'Sullivan, D.M., Bager, P.
ORCID: https://orcid.org/0000-0002-3577-8459, Maelbye, M., Bustamante, M., Torrent, M., Esplugues, A., Duijts, L.
ORCID: https://orcid.org/0000-0001-6731-9452, Hu, C., Elbert, N.J.
ORCID: https://orcid.org/0000-0001-5936-4050, Pasmans, S.G.M.A., Nijsten, T.E C., von Berg, A., Standl, M., Schikowski, T., Herberth, G., Heinrich, J.
ORCID: https://orcid.org/0000-0002-9620-1629, Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Lau, S.
ORCID: https://orcid.org/0000-0002-5189-4265, Curtin, J.A., Simpson, A., Custovic, A., Pennell, C.E., Wang, C.A., Holt, P.G.
ORCID: https://orcid.org/0000-0003-1193-0935, Bisgaard, H.
ORCID: https://orcid.org/0000-0003-4131-7592 and Bønnelykke, K.
Allergy 75
(6): 1481-1485.
June 2020
Phenotype consensus is required to enable large-scale genetic consortium studies of food allergy.
Asai, Y.
ORCID: https://orcid.org/0000-0003-1674-3215, Martino, D., Eiwegger, T.
ORCID: https://orcid.org/0000-0002-2914-7829, Nadeau, K.
ORCID: https://orcid.org/0000-0002-2146-2955, Koppelman, G.H., Clarke, A.E., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Chan, E.S., Simons, E., Laprise, C., Mazer, B., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Royce, D., Elliott, S.J., Hampson, C., Gerdts, J., Eslami, A., Soller, L.
ORCID: https://orcid.org/0000-0003-3542-3241, Hui, J., Azad, M.
ORCID: https://orcid.org/0000-0002-5942-4444, Sandford, A. and Daley, D.
Allergy 75
(9): 2383-2387.
23 April 2020
Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression.
Mucha, S., Baurecht, H., Novak, N., Rodríguez, E., Bej, S., Mayr, G., Emmert, H., Stölzl, D., Gerdes, S., Degenhardt, F., Hübenthal, M., Ellinghaus, E., Jung, E.S., Kässens, J.C., Wienbrandt, L., Lieb, W., Müller-Nurasyid, M., Hotze, M., Dand, N., Grosche, S.
ORCID: https://orcid.org/0000-0002-7658-0932, Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Arnold, A., Homuth, G., Schmidt, C.O., Wehkamp, U., Nöthen, M.M., Hoffmann, P., Paternoster, L., Standl, M., Bønnelykke, K., Ahluwalia, T.S., Bisgaard, H., Peters, A., Gieger, C., Waldenberger, M., Schulz, H., Strauch, K., Werfel, T., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Wolfien, M., Rosenstiel, P., Wolkenhauer, O., Schreiber, St., Franke, A., Weidinger, S. and Ellinghaus, D.
Journal of Allergy and Clinical Immunology 145
(4): 1208-1218.
April 2020
Eleven loci with new reproducible genetic associations with allergic disease risk.
Ferreira, M.A., Vonk, J.M., Baurecht, H., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, V., Lu, Y., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Hinds, D.A., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Weidinger, S., Magnusson, P.K., Jorgenson, E., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Boomsma, D.I., Karlsson, R., Almqvist, C., Koppelman, G.H. and Paternoster, L.
Journal of Allergy and Clinical Immunology 143
(2): 691-699.
February 2019
Evaluation of food allergy candidate loci in the Genetics of Food Allergy Study.
Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Grosche, S.
ORCID: https://orcid.org/0000-0002-7658-0932, Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Kalb, B., Blumchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Yürek, S., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Niggemann, B., Beyer, K. and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
Journal of Allergy and Clinical Immunology 142
(4): 1368-1370.
October 2018
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.
Waage, J., Standl, M., Curtin, J.A., Jessen, L.E.
ORCID: https://orcid.org/0000-0003-2879-2559, Thorsen, J.
ORCID: https://orcid.org/0000-0003-0200-0461, Tian, C., Schoettler, N., Flores, C.
ORCID: https://orcid.org/0000-0001-5352-069X, Abdellaoui, A., Ahluwalia, T.S.
ORCID: https://orcid.org/0000-0002-7464-3354, Alves, A.C., Amaral, A.F.S.
ORCID: https://orcid.org/0000-0002-0369-9449, Antó, J.M., Arnold, A., Barreto-Luis, A., Baurecht, H., van Beijsterveldt, C.E.M., Bleecker, E.R., Bonàs-Guarch, S., Boomsma, D.I., Brix, S.
ORCID: https://orcid.org/0000-0001-8951-6705, Bunyavanich, S.
ORCID: https://orcid.org/0000-0001-6108-439X, Burchard, E.G., Chen, Z., Curjuric, I., Custovic, A., den Dekker, H.T., Dharmage, S.C., Dmitrieva, J., Duijts, L., Ege, M.J.
ORCID: https://orcid.org/0000-0001-6643-3923, Gauderman, W.J., Georges, M., Gieger, C., Gilliland, F., Granell, R., Gui, H., Hansen, T.
ORCID: https://orcid.org/0000-0001-8748-3831, Heinrich, J., Henderson, J., Hernandez-Pacheco, N., Holt, P., Imboden, M., Jaddoe, V.W.V., Jarvelin, M.R., Jarvis, D.L., Jensen, K.K.
ORCID: https://orcid.org/0000-0001-9217-7142, Jónsdóttir, I.
ORCID: https://orcid.org/0000-0001-8339-150X, Kabesch, M., Kaprio, J.
ORCID: https://orcid.org/0000-0002-3716-2455, Kumar, A., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Levin, A.M., Li, X., Lorenzo-Diaz, F., Melén, E., Mercader, J.M.
ORCID: https://orcid.org/0000-0001-8494-3660, Meyers, D.A., Myers, R., Nicolae, D.L., Nohr, E.A., Palviainen, T.
ORCID: https://orcid.org/0000-0002-7847-8384, Paternoster, L., Pennell, C.E., Pershagen, G., Pino-Yanes, M.
ORCID: https://orcid.org/0000-0003-0332-437X, Probst-Hensch, N.M., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Simpson, A., Stefansson, K., Sunyer, J., Sveinbjornsson, G., Thiering, E., Thompson, P.J., Torrent, M., Torrents, D., Tung, J.Y., Wang, C.A.
ORCID: https://orcid.org/0000-0002-4301-3974, Weidinger, S., Weiss, S.
ORCID: https://orcid.org/0000-0001-7196-303X, Willemsen, G., Williams, L.K., Ober, C., Hinds, D.A.
ORCID: https://orcid.org/0000-0002-4911-803X, Ferreira, M.A., Bisgaard, H., Strachan, D.P. and Bønnelykke, K.
ORCID: https://orcid.org/0000-0003-2003-1018
Nature Genetics 50
(8): 1072-1080.
August 2018
A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.
Asai, Y., Eslami, A., van Ginkel, C.D., Akhabir, L., Wan, M., Yin, D., Ellis, G., Ben-Shoshan, M., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Martino, D., Ferreira, M.A., Allen, K., Mazer, B., de Groot, H., de Jong, N.W., Gerth van Wijk, R., Dubois, A.E.J., Grosche, S.
ORCID: https://orcid.org/0000-0002-7658-0932, Ashley, S.
ORCID: https://orcid.org/0000-0001-9973-9742, Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Kalb, B., Beyer, K., Nöthen, M.M., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Chin, R., Cheuk, S., Hoffman, J., Jorgensen, E., Witte, J.S., Melles, R.B., Hong, X., Wang, X., Hui, J., Musk, A.W.B., Hunter, M., James, A.L., Koppelman, G.H., Sandford, A.J., Clarke, A.E. and Daley, D.
Journal of Allergy and Clinical Immunology 141
(4): 1513-1516.
April 2018
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais, F., Margaritte-Jeannin, P., Barnes, K.C., Cookson, W.O.C., Altmüller, J.
ORCID: https://orcid.org/0000-0003-4372-1521, Ang, W., Barr, R.G., Beaty, T.H., Becker, A.B., Beilby, J., Bisgaard, H., Bjornsdottir, U.S., Bleecker, E., Bonnelykke, K., Boomsma, D.I., Bouzigon, E., Brightling, C.E., Brossard, M., Brusselle, G.G., Burchard, E., Burkart, K.M., Bush, A., Chan-Yeung, M., Chung, K.F., Couto Alves, A., Curtin, J.A., Custovic, A., Daley, D., de Jongste, J.C., Del-Rio-Navarro, B.E., Donohue, K.M., Duijts, L., Eng, C., Eriksson, J.G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M.A., Freidin, M.B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S.A, Gilliland, F., Granell, R., Graves, P.E., Gudbjartsson, D.F., Haahtela, T., Heckbert, S.R., Heederik, D., Heinrich, J., Helioevaara, M., Henderson, J., Himes, B.E., Hirose, H., Hirschhorn, J.N., Hofman, A., Holt, P., Hottenga, J., Hudson, T.J., Hui, J., Imboden, M., Ivanov, V., Jaddoe, V.W.V., James, A., Janson, C., Jarvelin, M.R., Jarvis, D., Jones, G., Jonsdottir, I., Jousilahti, P., Kabesch, M., Kähönen, M., Kantor, D.B., Karunas, A.S., Khusnutdinova, E., Koppelman, G.H., Kozyrskyj, A.L., Kreiner, E., Kubo, M., Kumar, R., Kumar, A., Kuokkanen, M., Lahousse, L., Laitinen, T., Laprise, C., Lathrop, M., Lau, S., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Lehtimaeki, T., Letort, S., Levin, A.M., Li, G., Liang, L., Loehr, L.R., London, S.J., Loth, D.W., Manichaikul, A., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Martinez, F.J., Matheson, M.C., Mathias, R.A., Matsumoto, K., Mbarek, H., McArdle, W.L., Melbye, M., Melen, E., Meyers, D., Michel, S., Mohamdi, H., Musk, A.W., Myers, R.A., Nieuwenhuis, M.A.E., Noguchi, E., O'Connor, G.T., Ogorodova, L.M., Palmer, C.D., Palotie, A., Park, J.E., Pennell, C.E., Pershagen, G., Polonikov, A., Postma, D.S., Probst-Hensch, N., Puzyrev, V.P., Raby, B.A., Raitakari, O.T., Ramasamy, A., Rich, S.S., Robertson, C.F., Romieu, I., Salam, M.T., Salomaa, V., Schluenssen, V., Scott, R., Selivanova, P.A., Sigsgaard, T., Simpson, A., Siroux, V., Smith, L.J., Solodilova, M., Standl, M., Stefansson, K., Strachan, D.P., Stricker, B.H., Takahashi, A., Thompson, P.J., Thorleifsson, G., Thorsteinsdottir, U., Tiesler, C.M.T., Torgerson, D.G., Tsunoda, T., Uitterlinden, A.G., van der Valk, R.J.P., Vaysse, A., Vedantam, S., von Berg, A., von Mutius, E., Vonk, J.M., Waage, J., Wareham, N.J., Weiss, S.T., White, W.B., Wickman, M., Widén, E., Willemsen, G., Williams, L.K., Wouters, I.M., Yang, J.J., Zhao, J.H., Moffatt, M.F., Ober, C. and Nicolae, D.L.
Nature Genetics 50
(1): 42-53.
January 2018
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Ferreira, M.A.
ORCID: https://orcid.org/0000-0001-9059-1825, Vonk, J.M., Baurecht, H., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, V., van Dongen, J., Lu, Yi, Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Esparza-Gordillo, J., Medway, C.W., Mountjoy, E.
ORCID: https://orcid.org/0000-0002-0626-1821, Burrows, K., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Grosche, S.
ORCID: https://orcid.org/0000-0002-7658-0932, Brumpton, B.M., Witte, J.S., Hottenga, J.J., Willemsen, G., Zheng, J., Rodriguez, E., Hotze, M., Franke, A.
ORCID: https://orcid.org/0000-0003-1530-5811, Revez, J.A., Beesley, J., Matheson, M.C., Dharmage, S.C., Bain, L.M., Fritsche, L.G., Gabrielsen, M.E., Balliu, B., Nielsen, J.B.
ORCID: https://orcid.org/0000-0002-6654-2852, Zhou, W., Hveem, K., Langhammer, A., Holmen, O.L., Løset, M., Abecasis, G.R., Willer, C.J.
ORCID: https://orcid.org/0000-0001-5645-4966, Arnold, A., Homuth, G., Schmidt, C.O., Thompson, P.J., Martin, N.G., Duffy, D.L., Novak, N., Schulz, H., Karrasch, S., Gieger, C., Strauch, K., Melles, R.B., Hinds, D.A., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Weidinger, S., Magnusson, P.K.E., Jansen, R.
ORCID: https://orcid.org/0000-0002-3333-6737, Jorgenson, E.
ORCID: https://orcid.org/0000-0002-5829-8191, Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Boomsma, D.I., Almqvist, C.
ORCID: https://orcid.org/0000-0002-1045-1898, Karlsson, R.
ORCID: https://orcid.org/0000-0002-8949-2587, Koppelman, G.H. and Paternoster, L.
Nature Genetics 49
(12): 1752-1757.
December 2017
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.
Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Grosche, S., Kalb, B., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Blümchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Röblitz, H., Yürek, S., Tschirner, S., Hong, X., Wang, X., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Niggemann, B., Beyer, K. and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
Nature Communications 8
(1): 1056.
20 October 2017
DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis.
Sarnowski, C., Laprise, C., Malerba, G., Moffatt, M.F., Dizier, M.H., Morin, A., Vincent, Q.B., Rohde, K., Esparza-Gordillo, J., Margaritte-Jeannin, P., Liang, L., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Bousquet, J., Siroux, V., Pignatti, P.F., Cookson, W.O., Lathrop, M., Pastinen, T., Demenais, F. and Bouzigon, E.
Journal of Allergy and Clinical Immunology 138
(3): 748-753.
September 2016
Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes.
Schmitt, J., Schwarz, K., Baurecht, H., Hotze, M., Fölster-Holst, R., Rodríguez, E., Lee, Y.A.E.
ORCID: https://orcid.org/0000-0002-1817-9163, Franke, A., Degenhardt, F., Lieb, W., Gieger, C., Kabesch, M., Nöthen, M.M., Irvine, A.D., McLean, W.H.I., Deckert, S., Stephan, V., Schwarz, P., Aringer, M., Novak, N. and Weidinger, S.
Journal of Allergy and Clinical Immunology 137
(1): 130-136.
January 2016
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D.P., Curtin, J.A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A.C., Thyssen, J.P., den Dekker, H.T., Ferreira, M.A., Altmaier, E., Sleiman, P.M.A., Xiao, F.L., Gonzalez, J.R., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Kalb, B., Pino-Yanes, M., Xu, C.J., Carstensen, L., Groen-Blokhuis, M.M., Venturini, C., Pennell, C.E., Barton, S.J., Levin, A.M., Curjuric, I., Bustamante, M., Kreiner-Møller, E., Lockett, G.A., Bacelis, J., Bunyavanich, S., Myers, R.A., Matanovic, A., Kumar, A., Tung, J.Y., Hirota, T., Kubo, M., McArdle, W.L., Henderson, A.J., Kemp, J.P., Zheng, J., Smith, G.D., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Bauerfeind, A., Lee-Kirsch, M.A., Arnold, A., Homuth, G., Schmidt, C.O., Mangold, E., Cichon, S., Keil, T., Rodríguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Fölster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L.L., Grarup, N., de Jongste, J.C., Rivadeneira, F., Hofman, A., Jaddoe, V.W.V., Pasmans, S.G.M.A., Elbert, N.J., Uitterlinden, A.G., Marks, G.B., Thompson, P.J., Matheson, M.C., Robertson, C.F., Ried, J.S., Li, J., Zuo, X.B., Zheng, X.D., Yin, X.Y., Sun, L.D., McAleer, M.A., O'Regan, G.M., Fahy, C.M.R., Campbell, L.E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D.S., Feenstra, B., Geller, F., Hottenga, J.J., Middeldorp, C.M., Hysi, P., Bataille, V., Spector, T., Tiesler, C.M.T., Thiering, E., Pahukasahasram, B., Yang, J.J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C.L., Myhre, R., Nystad, W., Custovic, A., Weiss, S.T., Meyers, D.A., Söderhäll, C., Melén, E., Ober, C., Raby, B.A., Simpson, A., Jacobsson, B., Holloway, J.W., Bisgaard, H., Sunyer, J., Probst-Hensch, N.M., Williams, L.K., Godfrey, K.M., Wang, C.A., Boomsma, D.I., Melbye, M., Koppelman, G.H., Jarvis, D., McLean, W.H.I., Irvine, A.D., Zhang, X.J., Hakonarson, H., Gieger, C., Burchard, E.G., Martin, N.G., Duijts, L., Linneberg, A., Jarvelin, M.R., Noethen, M.M., Lau, S., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Tamari, M., Hinds, D.A., Glass, D., Brown, S.J., Heinrich, J., Evans, D.M. and Weidinger, S.
Nature Genetics 47
(12): 1449-1456.
December 2015
Meta-analysis identifies seven susceptibility loci involved in the atopic march.
Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Esparza-Gordillo, J., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Bauerfeind, A., Strachan, D.P., Spycher, B.D., Baurecht, H., Margaritte-Jeannin, P., Sääf, A., Kerkhof, M., Ege, M., Baltic, S., Matheson, M.C., Li, J., Michel, S., Ang, W.Q., McArdle, W., Arnold, A., Homuth, G., Demenais, F., Bouzigon, E., Söderhäll, C., Pershagen, G., de Jongste, J.C., Postma, D.S., Braun-Fahrlaender, C., Horak, E., Ogorodova, L.M., Puzyrev, V.P., Bragina, E.Y., Hudson, T.J., Morin, C., Duffy, D.L., Marks, G.B., Robertson, C.F., Montgomery, G.W., Musk, B., Thompson, P.J., Martin, N.G., James, A., Sleiman, P., Toskala, E., Rodriguez, E., Fölster-Holst, R., Franke, A., Lieb, W., Gieger, C., Heinzmann, A., Rietschel, E., Keil, T., Cichon, S., Nöthen, M.M., Pennell, C.E., Sly, P.D., Schmidt, C.O., Matanovic, A., Schneider, V.
ORCID: https://orcid.org/0000-0002-3980-3789, Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Holt, P.G., Lau, S., Kabesch, M., Weidinger, S., Hakonarson, H., Ferreira, M.A.R., Laprise, C., Freidin, M.B., Genuneit, J., Koppelman, G.H., Melén, E., Dizier, M.H., Henderson, A.J. and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
Nature Communications 6
: 8804.
6 November 2015
Prediction and prevention of allergic rhinitis: A birth cohort study of 20 years.
Grabenhenrich, L.B., Keil, T., Reich, A., Gough, H., Beschorner, J., Hoffmann, U., Bauer, C.P., Forster, J., Schuster, A., Schramm, D., Nitsche, O., Zepp, F., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Bergmann, R., Bergmann, K., Wahn, U. and Lau, S.
Journal of Allergy and Clinical Immunology 136
(4): 932-940.
October 2015
A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis.
Schaarschmidt, H., Ellinghaus, D., Rodríguez, E., Kretschmer, A., Baurecht, H., Lipinski, S., Meyer-Hoffert, U., Harder, J., Lieb, W., Novak, N., Fölster-Holst, R., Esparza-Gordillo, J., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Ruschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Reischl, E., Waldenberger, M., Gieger, C., Illig, T., Kabesch, M., Zhang, X.J., Xiao, F.L., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Franke, A. and Weidinger, S.
Journal of Allergy and Clinical Immunology 136
(3): 802-806.
September 2015
eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues.
Huang, J., Chen, J., Esparza, J., Ding, J., Elder, J.T., Abecasis, G.R., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Lathrop, G.M., Moffatt, M.F., Cookson, W.O.C. and Liang, L.
Nature Communications 6
: 6821.
8 May 2015
Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.
Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Illig, T., Irvine, A.D., Kabesch, M., Lee, Y.A.E.
ORCID: https://orcid.org/0000-0002-1817-9163, Lieb, W., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, McLean, W.H.I., Morris, D.W., Mrowietz, U., Nair, R., Nöthen, M.M., Novak, N., O'Regan, G.M., Schreiber, S., Smith, C., Strauch, K., Stuart, P.E., Trembath, R., Tsoi, L.C., Weichenthal, M., Barker, J., Elder, J.T., Weidinger, S., Cordell, H.J. and Brown, S.J.
American Journal of Human Genetics 96
(1): 104-120.
8 January 2015
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.
Günther, C., Kind, B., Reijns, M.A.M., Berndt, N., Martinez-Bueno, M., Wolf, C., Tüngler, V., Chara, O., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Bicknell, L., Blum, S., Krug, C., Schmidt, F., Kretschmer, S., Koss, S., Astell, K.R., Ramantani, G., Bauerfeind, A., Morris, D.L., Cunninghame Graham, D.S., Bubeck, D., Leitch, A., Ralston, S.H., Blackburn, E.A., Gahr, M., Witte, T., Vyse, T.J., Melchers, I., Mangold, E., Nöthen, M.M., Aringer, M., Kuhn, A., Lüthke, K., Unger, L., Bley, A., Lorenzi, A., Isaacs, J.D., Alexopoulou, D., Conrad, K., Dahl, A., Roers, A., Alarcon-Riquelme, M.E., Jackson, A.P. and Lee-Kirsch, M.A.
Journal of Clinical Investigation 125
(1): 413-424.
2 January 2015
Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.
Scholtens, S., Postma, D.S., Moffatt, M.F., Panasevich, S., Granell, R., Henderson, A.J., Melen, E., Nyberg, F., Pershagen, G., Jarvis, D., Ramasamy, A., Wjst, M., Svanes, C., Bouzigon, E., Demenais, F., Kauffmann, F., Siroux, V., von Mutius, E., Ege, M.J., Braun-Fahrlaender, C., Genuneit, J., Brunekreef, B., Smit, H.A., Wijga, A.H., Kerkhof, M., Curjuric, I., Imboden, M., Thun, G.A., Probst-Hensch, N., Freidin, M.B., Bragina, E.I., Deev, I.A., Puzyrev, V.P., Daley, D., Park, J., Becker, A., Chan-Yeung, M., Kozyrskyj, A.L., Pare, P., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Lau, S., Keil, T., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Kabesch, M., Wijmenga, C., Franke, L., Nolte, I.M., Vonk, J., Kumar, A., Farrall, M., Cookson, W.O.C.M., Strachan, D.P., Koppelman, G.H. and Boezen, H.M.
Journal of Allergy and Clinical Immunology 133
(3): 885-888.
March 2014
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
Saunders, S.P., Goh, C.S.M., Brown, S.J., Palmer, C.N.A., Porter, R.M., Cole, C., Campbell, L.E., Gierlinski, M., Barton, G.J., Schneider, G., Balmain, A., Prescott, A.R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Tavendale, R., Mukhopadhyay, S., Turner, S.W., Madhok, V.B., Sullivan, F.M., Relton, C., Burn, J., Meggitt, S., Smith, C.H., Allen, M.A., Barker, J.N.W.N., Reynolds, N.J., Cordell, H.J., Irvine, A.D., McLean, W.H.I., Sandilands, A. and Fallon, P.G.
Journal of Allergy and Clinical Immunology 132
(5): 1121-1129.
November 2013
A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis.
Esparza-Gordillo, J., Schaarschmidt, H., Liang, L., Cookson, W., Bauerfeind, A., Lee-Kirsch, M.A., Nemat, K., Henderson, J., Paternoster, L., Harper, J.L., Mangold, E., Nothen, M.M., Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Kerscher, T., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Matanovic, A., Lau, S., Keil, T., Bauer, C.P., Kurek, M., Ciechanowicz, A., Macek, M., Franke, A., Kabesch, M., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Abecasis, G., Weidinger, S., Moffatt, M. and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
Journal of Allergy and Clinical Immunology 132
(2): 371-377.
August 2013
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.
Baud, A., Hermsen, R., Guryev, V., Stridh, P., Graham, D., McBride, M.W., Foroud, T., Calderari, S., Diez, M., Ockinger, J., Beyeen, A.D., Gillett, A., Abdelmagid, N., Guerreiro-Cacais, A.O., Jagodic, M., Tuncel, J., Norin, U., Beattie, E., Huynh, N., Miller, W.H., Koller, D.L., Alam, I., Falak, S., Osborne-Pellegrin, M., Martinez-Membrives, E., Canete, T., Blazquez, G., Vicens-Costa, E., Mont-Cardona, C., Diaz-Moran, S., Tobena, A., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Zelenika, D., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1575, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Bauerfeind, A., Bihoreau, M.T., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Rintisch, C., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Wheeler, D.A., Worley, K.C., Muzny, D.M., Gibbs, R.A., Lathrop, M., Lansu, N., Toonen, P., Ruzius, F.P., de Bruijn, E., Hauser, H., Adams, D.J., Keane, T., Atanur, S.S., Aitman, T.J., Flicek, P., Malinauskas, T., Jones, E.Y., Ekman, D., Lopez-Aumatell, R., Dominiczak, A.F., Johannesson, M., Holmdahl, R., Olsson, T., Gauguier, D., Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Fernandez-Teruel, A., Cuppen, E., Mott, R. and Flint, J.
Nature Genetics 45
(7): 767-775.
July 2013
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
Ellinghaus, D., Baurecht, H., Esparza-Gordillo, J., Rodríguez, E., Matanovic, A., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Schaarschmidt, H., Novak, N., Michel, S., Maintz, L., Werfel, T., Meyer-Hoffert, U., Hotze, M., Prokisch, H., Heim, K., Herder, C., Hirota, T., Tamari, M., Kubo, M., Takahashi, A., Nakamura, Y., Tsoi, L.C., Stuart, P., Elder, J.T., Sun, L., Zuo, X., Yang, S., Zhang, X., Hoffmann, P., Nöthen, M.M., Fölster-Holst, R., Winkelmann, J., Illig, T., Boehm, B.O., Duerr, R.H., Büning, C., Brandt, S., Glas, J., McAleer, M.A., Fahy, C.M., Kabesch, M., Brown, S., McLean, W.H.I., Irvine, A.D., Schreiber, S., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Franke, A. and Weidinger, S.
Nature Genetics 45
(7): 808-812.
July 2013
The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma.
Dizier, M.H., Margaritte-Jeannin, P., Madore, A.M., Esparza-Gordillo, J., Moffatt, M.F., Corda, E., Monier, F., Guilloud-Bataille, M., Franke, A., Weidinger, S., Annesi-Maesano, I., Just, J., Pin, I., Kauffmann, F., Cookson, W., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Laprise, C., Lathrop, M., Bouzigon, E. and Demenais, F.
Journal of Allergy and Clinical Immunology 129
(6): 1547-1553.
June 2012
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Petretto, E., Wallace, C., Bottolo, L., Rotival, M., Lu, H., Li, Y., Sarwar, R., Langley, S.R., Bauerfeind, A., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Paskas, S.
ORCID: https://orcid.org/0000-0002-1206-5376, Rintisch, C., Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Cooper, J., Buchan, R., Gray, E.E., Cyster, J.G., Braund, P., Gracey, J., Krishnan, U., Moore, J.S., Nelson, C.P., Pollard, H., Attwood, T., Crisp-Hihn, A., Foad, N., Jolley, J., Lloyd-Jones, H., Muir, D., Murray, E., O'Leary, K., Rankin, A., Sambrook, J., Godfroy, T., Brocheton, J., Proust, C., Schmitz, G., Heimerl, S., Lugauer, I., Belz, S., Gulde, S., Linsel-Nitschke, P., Sager, H., Schroeder, L., Lundmark, P., Syvannen, A.C., Neudert, J., Scholz, M., Deloukas, P., Gray, E., Gwilliams, R., Niblett, D., Erdmann, J., Hengstenberg, C., Maouche, S., Ouwehand, W.H., Rice, C.M., Samani, N.J., Schunkert, H., Goodall, A.H., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Roider, H.G., Vingron, M., Blankenberg, S., Muenzel, T., Zeller, T., Szymczak, S., Ziegler, A., Tiret, L., Smyth, D.J., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Aitman, T.J., Cambien, F., Clayton, D., Todd, J.A., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Cook, S.A.
Nature 467
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23 September 2010
A common variant on chromosome 11q13 is associated with atopic dermatitis.
Esparza-Gordillo, J., Weidinger, S., Foelster-Holst, R., Bauerfeind, A., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Rohde, K., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Schulz, F., Kerscher, T., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Wahn, U., Schreiber, S., Franke, A., Vogler, R., Heath, S., Baurecht, H., Novak, N., Rodriguez, E., Illig, T., Lee-Kirsch, M.A., Ciechanowicz, A., Kurek, M., Piskackova, T., Macek, M., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163 and Ruether, A.
Nature Genetics 41
(5): 596-601.
May 2009
SNP and haplotype mapping for genetic analysis in the rat.
Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Beck, A., Bihoreau, M.T., Birney, E., Brocklebank, D., Chen, Y., Cuppen, E., Demonchy, S., Dopazo, J., Flicek, P., Foglio, M., Fujiyama, A., Gut, I.G., Gauguier, D., Guigo, R., Guryev, V., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Jahn, N., Klages, S., Kren, V., Kube, M., Kuhl, H., Kuramoto, T., Kuroki, Y., Lechner, D., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Lopez-Bigas, N., Lathrop, G.M., Mashimo, T., Medina, I., Mott, R., Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Perrier-Cornet, J.A., Platzer, M., Pravenec, M.
ORCID: https://orcid.org/0000-0001-9197-5871, Reinhardt, R., Sakaki, Y., Schilhabel, M., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Serikawa, T., Shikhagaie, M., Tatsumoto, S., Taudien, S., Toyoda, A., Voigt, B., Zelenika, D., Zimdahl, H. and Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Genetics 40
(5): 560-566.
May 2008
G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth.
Pasternack, S.M., von Kuegelgen, I., Aboud, K.A., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Voss, K., Hillmer, A.M., Molderings, G.J., Franz, T., Ramirez, A., Nuernberg, P., Noethen, M.M. and Betz, R.C.
Nature Genetics 40
(3): 329-334.
March 2008
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.
Lee-Kirsch, M.A., Gong, M.
ORCID: https://orcid.org/0000-0001-7384-3429, Chowdhury, D., Senenko, L., Engel, K., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, de Silva, U., Bailey, S.L., Witte, T., Vyse, T.J., Kere, J., Pfeiffer, C., Harvey, S., Wong, A., Koskenmies, S., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Rohde, K., Schmidt, R.E., Dominiczak, A.F., Gahr, M., Hollis, T., Perrino, F.W., Lieberman, J. and Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Genetics 39
(9): 1065-1067.
September 2007
Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis.
Soederhaell, C., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Kerscher, T., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Esparza-Gordillo, J., Worm, M., Gruber, C., Mayr, G., Albrecht, M., Rohde, K., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Wahn, U., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
PLoS Biology 5
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September 2007
Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.
Schumacher, J., Kaneva, R., Jamra, R.A., Diaz, G.O., Ohlraun, S., Milanova, V., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Rivas, F., Mayoral, F., Fuerst, R., Flaquer, A., Windemuth, C., Gay, E., Sanz, S., Gonzalez, M.J., Gil, S., Cabaleiro, F., del Rio, F., Perez, F., Haro, J., Kostov, C., Chorbov, V., Nikolova-Hill, A., Stoyanova, V., Onchev, G., Kremensky, I., Strauch, K., Schulze, T.G., Nuernberg, P., Gaebel, W., Klimke, A., Auburger, G., Wienker, T.F., Kalaydjieva, L., Propping, P., Cichon, S., Jablensky, A., Rietschel, M. and Noethen, M.M.
American Journal of Human Genetics 77
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1 December 2005
A SNP map of the rat genome generated from cDNA sequences.
Zimdahl, H., Nyakatura, G., Brandt, P., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Fartmann, B., Brett, D., Droege, M., Monti, J., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Sun, Y.Y., Zhao, S.Y., Winter, E.E., Ponting, C.P., Chen, Y., Kasprzyk, A., Birney, E., Ganten, D. and Hubner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Science 303
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1 January 2004
Mutations in CAV3 cause mechanical hyperirritability of skeletal muscle in rippling muscle disease.
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The Case: Is this hemolytic uremic syndrome?
Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718, Düttmann, W., Brand, A. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Kidney International 102
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November 2022
Epigenetic "transgenerational" inheritance.
Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 146
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4 October 2022
Translating plasma sodium, stores, and hydration state from mouse to man.
Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
European Heart Journal 43
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14 September 2022
Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M.
ORCID: https://orcid.org/0000-0001-7132-8079, Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M.
ORCID: https://orcid.org/0000-0002-9373-4753, Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Butter, C., Felix, S.B., Otto, O., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Slevogt, H. and Fielitz, J.
ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 12
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December 2021
Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting.
Zanders, L.
ORCID: https://orcid.org/0000-0003-0488-6243, Kny, M.
ORCID: https://orcid.org/0000-0001-7132-8079, Hahn, A., Schmidt, S., Wundersitz, S., Todiras, M.
ORCID: https://orcid.org/0000-0002-9373-4753, Lahmann, I.
ORCID: https://orcid.org/0000-0003-0640-4519, Bandyopadhyay, A., Wollersheim, T., Kaderali, L., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872, Weber-Carstens, S. and Fielitz, J.
ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 13
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February 2021
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Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Cardiovascular Research 117
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1 January 2021
Salt and cardiovascular disease: insufficient evidence to recommend low sodium intake.
O'Donnell, M., Mente, A., Alderman, M.H., Brady, A.J.B., Diaz, R., Gupta, R., López-Jaramillo, P.
ORCID: https://orcid.org/0000-0002-9122-8742, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Lüscher, T.F., Mancia, G.
ORCID: https://orcid.org/0000-0003-0942-3176, Mann, J.F.E., McCarron, D.
ORCID: https://orcid.org/0000-0001-7568-5487, McKee, M.
ORCID: https://orcid.org/0000-0002-0121-9683, Messerli, F.H., Moore, L.L., Narula, J., Oparil, S.
ORCID: https://orcid.org/0000-0002-7505-2599, Packer, M.
ORCID: https://orcid.org/0000-0003-1828-2387, Prabhakaran, D., Schutte, A.
ORCID: https://orcid.org/0000-0001-9217-4937, Sliwa, K., Staessen, J.A., Yancy, C. and Yusuf, S.
European Heart Journal 41
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14 September 2020
Norman M. Kaplan: January 2, 1931-April 5, 2020.
Townsend, R.R.
ORCID: https://orcid.org/0000-0002-3215-9118, DiPette, D.J., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Weinberger, M.H. and Ram, V.
Hypertension 76
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August 2020
Phosphodiesterase 3A and arterial hypertension.
Ercu, M., Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Schächterle, C., Tsvetkov, D.
ORCID: https://orcid.org/0000-0002-6472-971X, Cui, Y., Maghsodi, S., Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Zühlke, K., Gregersen, N., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Hodge, R., Mühl, A., Pohl, B., Molé-Illas, R., Geelhaar, A., Walter, S., Napieczynska, H.
ORCID: https://orcid.org/0000-0001-5091-1185, Schelenz, S., Taube, M., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Anistan, Y.M., Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Todiras, M.
ORCID: https://orcid.org/0000-0002-9373-4753, Plehm, R., Popova, E.
ORCID: https://orcid.org/0000-0002-3043-9650, Langanki, R., Eichhorst, J., Lehmann, M., Wiesner, B., Russwurm, M., Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Kamer, I., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Gollasch, M.
ORCID: https://orcid.org/0000-0003-2797-1934, Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Klussmann, E.
ORCID: https://orcid.org/0000-0003-4004-5003
Circulation 142
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14 July 2020
RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738, Foster, D.J., Cunningham, M.W., Bercher, J., Nguyen, T., Shulga-Morskaya, S., Milstein, S., Shaikh, S., Rollins, J., Golic, M.
ORCID: https://orcid.org/0000-0003-3030-2678, Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, Kräker, K.
ORCID: https://orcid.org/0000-0002-4032-5382, Bendix, I.
ORCID: https://orcid.org/0000-0002-9751-3640, Serdar, M., Napieczynska, H.
ORCID: https://orcid.org/0000-0001-5091-1185, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Gellhaus, A., Thiele, K., Wallukat, G., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, LaMarca, B. and Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080
Journal of Clinical Investigation 130
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1 June 2020
B-cell lymphoma/leukemia 10 and angiotensin II-induced kidney injury.
Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Park, J.K., Henke, N., Rong, S., Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Klamer, S., Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Ruland, J., Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Cardiovascular Research 116
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1 April 2020
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M.
ORCID: https://orcid.org/0000-0001-7132-8079, Pablo-Tortola, C., Todiras, M.
ORCID: https://orcid.org/0000-0002-9373-4753, Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M.
ORCID: https://orcid.org/0000-0002-0513-3254, Jarosch, E.
ORCID: https://orcid.org/0000-0002-5897-3492, Sommer, T.
ORCID: https://orcid.org/0000-0001-9990-5202, Bröker, B.M., Felix, S.B., Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Weber-Carstens, S., Butter, C., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Fielitz, J.
ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 11
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February 2020
Reorganization of inter-chromosomal interactions in the 2q37-deletion syndrome.
Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Weise, A., Rittscher, K.
ORCID: https://orcid.org/0000-0001-8729-1602, Lichtenwald, J., Barutcu, A.R., Liehr, T., Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Wefeld-Neuenfeld, Y., Pölsler, L., Tinschert, S., Rinn, J.L.
ORCID: https://orcid.org/0000-0002-7231-7539, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755
EMBO Journal 37
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1 August 2018
Salt-responsive gut commensal modulates T(H)17 axis and disease.
Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Matus, M.G., Kearney, S.M., Olesen, S.W., Forslund, K.
ORCID: https://orcid.org/0000-0003-4285-6993, Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Haase, S., Mähler, A.
ORCID: https://orcid.org/0000-0002-3904-5789, Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Vvedenskaya, O.
ORCID: https://orcid.org/0000-0001-7808-269X, Kleiner, F.H., Tsvetkov, D.
ORCID: https://orcid.org/0000-0002-6472-971X, Klug, L., Costea, P.I., Sunagawa, S., Maier, L., Rakova, N.
ORCID: https://orcid.org/0000-0002-5397-6715, Schatz, V., Neubert, P., Frätzer, C., Krannich, A.
ORCID: https://orcid.org/0000-0002-4025-6495, Gollasch, M.
ORCID: https://orcid.org/0000-0003-2797-1934, Grohme, D.A., Côrte-Real, B.F., Gerlach, R.G., Basic, M., Typas, A., Wu, C., Titze, J.M., Jantsch, J., Boschmann, M.
ORCID: https://orcid.org/0000-0002-0114-7114, Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299, Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Linker, R.A., Alm, E.J. and Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Nature 551
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30 November 2017
Disturbed placental imprinting in preeclampsia leads to altered expression of DLX5, a human-specific early trophoblast marker.
Zadora, J.
ORCID: https://orcid.org/0000-0002-6906-7815, Singh, M.
ORCID: https://orcid.org/0000-0002-8626-5418, Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, Przybyl, L.
ORCID: https://orcid.org/0000-0001-9777-8879, Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738, Golic, M.
ORCID: https://orcid.org/0000-0003-3030-2678, Yung, H.W., Huppertz, B., Cartwright, J.E., Whitley, G.S., Johnsen, G.M., Levi, G., Isbruch, A., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Staff, A.C., Hurst, L.D., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Izsvák, Z.
ORCID: https://orcid.org/0000-0002-2053-2384
Circulation 136
(19): 1824-1839.
7 November 2017
Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets.
Eulenberg-Gustavus, C.
ORCID: https://orcid.org/0000-0002-2425-2275, Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Maass, P.
ORCID: https://orcid.org/0000-0002-2742-8301, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718
Journal of Experimental Medicine 214
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3 July 2017
High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
Kitada, K., Daub, S., Zhang, Y., Klein, J. D., Nakano, D., Pedchenko, T., Lantier, L., LaRocque, L.M., Marton, A., Neubert, P., Schröder, A., Rakova, N.
ORCID: https://orcid.org/0000-0002-5397-6715, Jantsch, J., Dikalova, A.E., Dikalov, S.I., Harrison, D.G., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Nishiyama, A., Rauh, M., Harris, R. C., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Wassermann, D.H., Sands, J.M. and Titze, J.
Journal of Clinical Investigation 127
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1 May 2017
Increased salt consumption induces body water conservation and decreases fluid intake.
Rakova, N.
ORCID: https://orcid.org/0000-0002-5397-6715, Kitada, K., Lerchl, K., Dahlmann, A., Birukov, A.
ORCID: https://orcid.org/0000-0002-8306-3351, Daub, S., Kopp, C., Pedchenko, T., Zhang, Y., Beck, L., Johannes, B., Marton, A., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Rauh, M., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Titze, J.
Journal of Clinical Investigation 127
(5): 1932-1943.
1 May 2017
The technical report on sodium intake and cardiovascular disease in low- and middle-income countries by the joint working group of the World Heart Federation, the European Society of Hypertension and the European Public Health Association.
Mancia, G., Oparil, S., Whelton, P.K., McKee, M., Dominiczak, A., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, AlHabib, K., Lanas, F., Damasceno, A., Prabhakaran, D., La Torre, G., Weber, M., O'Donnell, M., Smith, S.C. and Narula, J.
European Heart Journal 38
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7 March 2017
Risk factors: evolving epidemiology of sodium intake and CVD.
Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Nature Reviews Cardiology 13
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August 2016
CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia.
Przybyl, L.
ORCID: https://orcid.org/0000-0001-9777-8879, Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738, Golic, M.
ORCID: https://orcid.org/0000-0003-3030-2678, Rugor, J., Solano, M.E., Arck, P.C., Gauster, M., Huppertz, B., Emontzpohl, C., Stoppe, C., Bernhagen, J., Leng, L., Bucala, R., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Weedon-Fekjær, S., Johnsen, G.M., Peetz, D., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Staff, A.C., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134
Circulation Research 119
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24 June 2016
11-β hydroxysteroid dehydrogenase-2 and salt-sensitive hypertension.
Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 133
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5 April 2016
Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine.
Haghikia, A., Jörg, S., Duscha, A., Berg, J., Manzel, A., Waschbisch, A., Hammer, A., Lee, D.H., May, C., Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Ostermann, A.I., Schebb, N.H., Akkad, D.A., Grohme, D.A., Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299, Thöne, J., Demir, S., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Gold, R. and Linker, R.A.
Immunity 43
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20 October 2015
PDE3A mutations cause autosomal dominant hypertension with brachydactyly.
Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Schächterle, C., Weise, A., Stricker, S., Lindschau, C.
ORCID: https://orcid.org/0000-0003-1960-099X, Vaegler, M., Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Toka, H.R., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Krawitz, P.M.
ORCID: https://orcid.org/0000-0002-3194-8625, Parkhomchuk, D., Hecht, J., Hollfinger, I.
ORCID: https://orcid.org/0000-0002-6233-8395, Wefeld-Neuenfeld, Y., Bartels-Klein, E., Mühl, A., Kann, M., Schuster, H., Chitayat, D., Bialer, M.G., Wienker, T.F., Ott, J., Rittscher, K., Liehr, T., Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706, Plessis, G., Tank, J., Mai, K., Naraghi, R., Hodge, R., Hopp, M., Hattenbach, L.O., Busjahn, A., Rauch, A., Vandeput, F., Gong, M.
ORCID: https://orcid.org/0000-0001-7384-3429, Rüschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Haller, H., Mundlos, S., Bilginturan, N., Movsesian, M.A., Klussmann, E.
ORCID: https://orcid.org/0000-0003-4004-5003, Toka, O. and Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755
Nature Genetics 47
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June 2015
Cutaneous Na(+) storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense.
Jantsch, J., Schatz, V., Friedrich, D., Schröder, A., Kopp, C., Siegert, I., Maronna, A., Wendelborn, D., Linz, P., Binger, K.J.
ORCID: https://orcid.org/0000-0003-1139-3308, Gebhardt, M., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Neubert, P., Fischer, F., Teufel, S., David, J.P., Neufert, C., Cavallaro, A., Rakova, N.
ORCID: https://orcid.org/0000-0002-5397-6715, Küper, C., Beck, F.X., Neuhofer, W., Muller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Schuler, G., Uder, M., Bogdan, C., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Titze, J.
Cell Metabolism 21
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3 March 2015
Immune cells control skin lymphatic electrolyte homeostasis and blood pressure.
Wiig, H.
ORCID: https://orcid.org/0000-0002-7740-8210, Schröder, A., Neuhofer, W., Jantsch, J., Kopp, C., Karlsen, T.V., Boschmann, M.
ORCID: https://orcid.org/0000-0002-0114-7114, Goss, J., Bry, M., Rakova, N.
ORCID: https://orcid.org/0000-0002-5397-6715, Dahlmann, A., Brenner, S., Tenstad, O., Nurmi, H., Mervaala, E., Wagner, H., Beck, F.X., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Kerjaschki, D., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Harrison, D.G., Alitalo, K. and Titze, J.
Journal of Clinical Investigation 123
(7): 2803-2815.
1 July 2013
Critical illness myopathy and GLUT4 - significance of insulin and muscle contraction.
Weber-Carstens, S., Schneider, J.
ORCID: https://orcid.org/0000-0001-8810-0492, Wollersheim, T., Assmann, A., Bierbrauer, J., Marg, A.
ORCID: https://orcid.org/0000-0003-3673-4244, Al Hasani, H., Chadt, A., Wenzel, K., Koch, S., Fielitz, J.
ORCID: https://orcid.org/0000-0001-8522-1045, Kleber, C., Faust, K., Mai, K., Spies, C.D., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Boschmann, M.
ORCID: https://orcid.org/0000-0002-0114-7114, Spranger, J. and Spuler, S.
ORCID: https://orcid.org/0000-0002-0155-1117
American Journal of Respiratory and Critical Care Medicine 187
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15 February 2013
Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance.
Rakova, N.
ORCID: https://orcid.org/0000-0002-5397-6715, Jüttner, K., Dahlmann, A., Schröder, A., Linz, P., Kopp, C., Rauh, M., Goller, U., Beck, L., Agureev, A., Vassilieva, G., Lenkova, L., Johannes, B., Wabel, P., Moissl, U., Vienken, J., Gerzer, R., Eckardt, K.U., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Kirsch, K., Morukov, B., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Titze, J.
Cell Metabolism 17
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8 January 2013
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.
Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, LaMarca, B., Hubel, C.A., Kaartokallio, T., Lokki, A.I., Ekholm, E., Laivuori, H., Gauster, M., Huppertz, B., Sugulle, M., Ryan, M.J., Novotny, S., Brewer, J., Park, J.K., Kacik, M., Hoyer, J., Verlohren, S.
ORCID: https://orcid.org/0000-0003-3507-8636, Wallukat, G., Rothe, M.
ORCID: https://orcid.org/0000-0002-6813-4705, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Muller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Schunck, W.H.
ORCID: https://orcid.org/0000-0001-7965-7731, Staff, A.C. and Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080
Circulation 126
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18 December 2012
A misplaced lncRNA causes brachydactyly in humans.
Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Rump, A., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Stricker, S., Schulze, L., Platzer, K., Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Tinschert, S., Goldring, M.B., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755
Journal of Clinical Investigation 122
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1 November 2012
Rats, salt, and history.
Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Cell Metabolism 15
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8 February 2012
Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage a multicenter prospective cohort study.
Nickolas, T.L., Schmidt-Ott, K.M.
ORCID: https://orcid.org/0000-0002-7700-7142, Canetta, P., Forster, C., Singer, E., Sise, M., Elger, A., Maarouf, O., Sola-Del Valle, D.A., O'Rourke, M., Sherman, E., Lee, P., Geara, A., Imus, P., Guddati, A., Polland, A., Rahman, W., Elitok, S., Malik, N., Giglio, J., El-Sayegh, S., Devarajan, P., Hebbar, S., Saggi, S.J., Hahn, B., Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Barasch, J.
Journal of the American College of Cardiology 59
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17 January 2012
Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects.
Haufe, S., Engeli, S., Kast, P., Boehnke, J., Utz, W., Haas, V., Hermsdorf, M., Maehler, A.
ORCID: https://orcid.org/0000-0002-3904-5789, Wiesner, S., Birkenfeld, A.L., Sell, H., Otto, C., Mehling, H., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Eckel, J., Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Boschmann, M.
ORCID: https://orcid.org/0000-0002-0114-7114 and Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706
Hepatology 53
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May 2011
Pathophysiology and management of hypokalemia: a clinical perspective.
Unwin, R.J., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Shirley, D.G.
Nature Reviews Nephrology 7
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February 2011
The molecular and cellular identity of peripheral osmoreceptors.
Lechner, S.G.
ORCID: https://orcid.org/0000-0001-9402-9127, Markworth, S., Poole, K., Smith, E.S.J.
ORCID: https://orcid.org/0000-0002-2699-1979, Lapatsina, L., Frahm, S.
ORCID: https://orcid.org/0000-0001-5645-2557, May, M., Pischke, S., Suzuki, M., Ibanez-Tallon, I., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706 and Lewin, G.R.
ORCID: https://orcid.org/0000-0002-2890-6352
Neuron 69
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27 January 2011
Divergent effects of central and peripheral renin on body weight and metabolism.
Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Cell Metabolism 12
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3 November 2010
Novel baroreflex activation therapy in resistant hypertension results of a European multi-center feasibility study.
Scheffers, I.J., Kroon, A.A., Schmidli, J., Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706, Tordoir, J.J., Mohaupt, M.G., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Haller, H., Menne, J., Engeli, S., Ceral, J., Eckert, S., Erglis, A., Narkiewicz, K., Philipp, T. and de Leeuw, P.W.
Journal of the American College of Cardiology 56
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5 October 2010
Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon: their potential impact for early risk assessment in asymptomatic Chagas' patients.
Munoz Saravia, S.G., Haberland, A., Bartel, S., Araujo, R., Valda, G., Duchen, D., Diaz Ramirez, I., Borges, A.C., Wallukat, G. and Schimke, I.
Journal of the American College of Cardiology 56
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3 August 2010
Cardiac involvement in sporadic inclusion-body myositis.
Utz, W., Schmidt, S., Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Luft, F.
ORCID: https://orcid.org/0000-0002-8635-1199 and Spuler, S.
ORCID: https://orcid.org/0000-0002-0155-1117
Circulation 121
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9 February 2010
Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon their potential impact for early risk assessment in asymptomatic Chagas' patients.
Wallukat, G., Munoz Saravia, S.G., Haberland, A., Bartel, S., Araujo, R., Valda, G., Duchen, D., Diaz Ramirez, I., Borges, A.C. and Schimke, I.
Journal of the American College of Cardiology 55
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2 February 2010
Regulatory T cells ameliorate angiotensin II-induced cardiac damage.
Kvakan, H., Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Park, J.K., Fischer, R.
ORCID: https://orcid.org/0000-0002-4828-2882, Schwarz, I., Rahn, H.P.
ORCID: https://orcid.org/0000-0002-5233-3937, Plehm, R., Wellner, M., Elitok, S., Gratze, P., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Circulation 119
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9 June 2009
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
Machnik, A., Neuhofer, W., Jantsch, J., Dahlmann, A., Tammela, T., Machura, K., Park, J.K., Beck, F.X., Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Derer, W., Goss, J., Ziomber, A., Dietsch, P., Wagner, H., van Rooijen, N., Kurtz, A., Hilgers, K.F., Alitalo, K., Eckardt, K.U., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Kerjaschki, D. and Titze, J.
Nature Medicine 15
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May 2009
BK channels in innate immune functions of neutrophils and macrophages.
Essin, K., Gollasch, M.
ORCID: https://orcid.org/0000-0003-2797-1934, Rolle, S.
ORCID: https://orcid.org/0000-0002-1909-687X, Weissgerber, P., Sausbier, M., Bohn, E., Autenrieth, I.B., Ruth, P., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Nauseef, W.M. and Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718
Blood 113
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5 February 2009
Angiogenesis factors and preeclampsia.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Nature Medicine 14
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November 2008
Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
Gratze, P., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Stocker, C., Park, J.K., Feldt, S., Shagdarsuren, E., Wellner, M., Gueler, F., Rong, S., Gross, V., Obst, M., Plehm, R., Alenina, N.
ORCID: https://orcid.org/0000-0002-6071-5433, Zenclussen, A., Titze, J., Small, K., Yokota, Y., Zenke, M., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Circulation 117
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20 May 2008
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
Monti, J., Fischer, J.
ORCID: https://orcid.org/0000-0003-0398-7720, Paskas, S.
ORCID: https://orcid.org/0000-0002-1206-5376, Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Goesele, C., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Fischer, R.
ORCID: https://orcid.org/0000-0002-4828-2882, Schmidt, C., Schirdewan, A., Gross, V., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Maatz, H.
ORCID: https://orcid.org/0000-0002-9232-6272, Patone, G.
ORCID: https://orcid.org/0000-0002-7242-0341, Saar, K.
ORCID: https://orcid.org/0000-0002-4483-1557, Vingron, M., Weldon, S.M., Lindpaintner, K., Hammock, B.D., Rohde, K., Dietz, R., Cook, S.A., Schunck, W.H.
ORCID: https://orcid.org/0000-0001-7965-7731, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Genetics 40
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May 2008
NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils.
von Vietinghoff, S., Tunnemann, G.
ORCID: https://orcid.org/0000-0001-6485-1136, Eulenberg, C.
ORCID: https://orcid.org/0000-0002-2425-2275, Wellner, M., Cardoso, M.C., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718
Blood 109
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15 May 2007
Pseudo-pseudo Meigs' syndrome.
Schmitt, R., Weichert, W., Schneider, W., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718
Lancet 366
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5 November 2005
Plasma exchange for primary autoimmune autonomic failure.
Schroeder, C., Vernino, S., Birkenfeld, A.L., Tank, J., Heusser, K., Lipp, A., Benter, T., Lindschau, C.
ORCID: https://orcid.org/0000-0003-1960-099X, Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706
New England Journal of Medicine 353
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13 October 2005
Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice.
Sausbier, M., Arntz, C., Bucurenciu, I., Zhao, H., Zhou, X.B., Sausbier, U., Feil, S., Kamm, S., Essin, K., Sailer, C.A., Abdullah, U., Krippeit-Drews, P., Feil, R., Hofmann, F., Knaus, H.G., Kenyon, C., Shipston, M.J., Storm, J.F., Neuhuber, W., Korth, M., Schubert, R., Gollasch, M.
ORCID: https://orcid.org/0000-0003-2797-1934 and Ruth, P.
Circulation 112
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5 July 2005
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection (authors reply inN Engl J Med. 2005 May 12;352(19):2027-8).
Dragun, D., Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Braesen, J.H., Fritsche, L., Nieminen-Kelhae, M., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Kintscher, U., Rudolph, B., Hoebeke, J., Eckert, D., Mazak, I., Plehm, R., Schoenemann, C., Unger, T., Budde, K., Neumayer, H.H., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Wallukat, G.
New England Journal of Medicine 352
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1 January 2005
Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.
Fiebeler, A., Nussberger, J., Shagdarsuren, E., Rong, S., Hilfenhaus, G.
ORCID: https://orcid.org/0000-0001-8764-077X, Al-Saadi, N., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Wellner, M., Meiners, S., Maser-Gluth, C., Jeng, A.Y., Webb, R.L., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Circulation 111
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1 January 2005
Paracrine role for periadventitial adipose tissue in the regulation of arterial tone.
Gollasch, M.
ORCID: https://orcid.org/0000-0003-2797-1934 and Dubrovska, G.
ORCID: https://orcid.org/0000-0001-8803-3541
Trends in Pharmacological Sciences 25
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1 December 2004
Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells.
Mazak, I., Fiebeler, A., Muller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Park, J.K., Shagdarsuren, E., Lindschau, C.
ORCID: https://orcid.org/0000-0003-1960-099X, Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Viedt, C., Pilz, B., Haller, H. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 109
(22): 2792-2800.
8 June 2004
Axoplasmic importins enable retrograde injury signaling in lesioned nerve.
Hanz, S., Perlson, E., Willis, D., Zheng, J.Q., Massarwa, R., Huerta, J.J., Koltzenburg, M., Koehler, M., van Minnen, J., Twiss, J.L. and Fainzilber, M.
Neuron 40
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18 December 2003
Inhibition of NF-κ B by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.
Choi, M.
ORCID: https://orcid.org/0000-0002-0286-1491, Rolle, S.
ORCID: https://orcid.org/0000-0002-1909-687X, Wellner, M., Cardoso, M.C.
ORCID: https://orcid.org/0000-0001-8427-8859, Scheidereit, C.
ORCID: https://orcid.org/0000-0002-0446-6129, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Kettritz, R.
ORCID: https://orcid.org/0000-0001-5821-6718
Blood 102
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15 September 2003
A splice mutation in a Syrian autosomal recessive hypercholesterolemia family causes a two-nucleotide deletion of mRNA.
Al Kateb, H., Bautz, E.K.F., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755
Circulation Research 93
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5 September 2003
Hydroxymethylglutaryl coenzyme A reductase inhibition reduces Chlamydia pneumoniae-induced cell interaction and activation.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Gieffers, J., Dietz, R., Joerres, A., Rupp, J., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Maass, M.
Circulation 108
(3): 261-265.
22 July 2003
The renal arterial resistance index and renal allograft survival.
Radermacher, J., Mengel, M., Ellis, S., Stuht, S., Hiss, M., Schwarz, A., Eisenberger, U., Burg, M., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Gwinner, W. and Haller, H.
New England Journal of Medicine 349
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10 July 2003
Selective impairment in sympathetic vasomotor control with norepinephrine transporter inhibition.
Tank, J., Schroeder, C., Diedrich, A., Szczech, E., Haertter, S., Sharma, A.M., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706
Circulation 107
(23): 2949-2954.
17 June 2003
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Viedt, C., Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Ugele, B., Brandes, R.P., Wallukat, G., Park, J.K., Janke, J.
ORCID: https://orcid.org/0000-0003-0113-4118, Barta, P., Theuer, J., Fiebeler, A., Homuth, V., Dietz, R., Haller, H., Kreuzer, J. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 107
(12): 1632-1639.
1 April 2003
Water drinking acutely improves orthostatic tolerance in healthy subjects.
Schroeder, C., Bush, V.E., Norcliffe, L.J., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Tank, J., Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706 and Hainsworth, R.
Circulation 106
(22): 2806-2811.
26 November 2002
Paradoxical effect of sibutramine on autonomic cardiovascular regulation.
Birkenfeld, A.L., Schroeder, C., Boschmann, M.
ORCID: https://orcid.org/0000-0002-0114-7114, Tank, J., Franke, G., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Biaggioni, I., Sharma, A.M. and Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706
Circulation 106
(19): 2459-2465.
5 November 2002
Homocysteine and risk of ischemic heart disease and stroke - a meta-analysis.
JAMA: Journal of the American Medical Association 288
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23 October 2002
Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huet anomaly).
Hoffmann, K., Dreger, C.K., Olins, A.L., Olins, D.E., Shultz, L.D., Lucke, B., Karl, H., Kaps, R., Mueller, D., Vaya, A., Aznar, J., Ware, R.E., Cruz, N.S., Lindner, T.H., Herrmann, H., Reis, A. and Sperling, K.
Nature Genetics 31
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August 2002
Catechol-O-methyltransferase and blood pressure in humans.
Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706, Lipp, A., Tank, J., Schroeder, C., Stoffels, M., Franke, G., Diedrich, A., Arnold, G., Goldstein, D.S., Sharma, A.M. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 106
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23 July 2002
Baroreflex buffering and susceptibility to vasoactive drugs.
Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706, Tank, J., Shannon, J.R., Diedrich, A., Lipp, A., Schroeder, C., Arnold, G., Sharma, A.M., Biaggioni, I., Robertson, D. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 105
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26 March 2002
Selective norepinephrine reuptake inhibition as a human model of orthostatic intolerance.
Schroeder, C., Tank, J., Boschmann, M.
ORCID: https://orcid.org/0000-0002-0114-7114, Diedrich, A., Sharma, A.M., Biaggioni, I., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706
Circulation 105
(3): 347-353.
22 January 2002
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice.
Drab, M., Verkade, P., Elger, M., Kasper, M., Lohn, M., Lauterbach, B., Menne, J., Lindschau, C.
ORCID: https://orcid.org/0000-0003-1960-099X, Mende, F., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Schedl, A., Haller, H. and Kurzchalia, T.V.
Science 293
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28 September 2001
Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Fiebeler, A., Park, J.K., Muller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Theuer, J., Mervaala, E., Bieringer, M., Gulba, D., Dietz, R., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Haller, H.
Circulation 104
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1 January 2001
Altered autonomic support of arterial blood pressure with age in healthy men.
Jones, P.P., Shapiro, L.F., Keisling, G.A., Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706, Shannon, J.R., Quaife, R.A. and Seals, D.R.
Circulation 104
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1 January 2001
A region on chromosome 3 is linked to dizygotic twinning.
Busjahn, A., Knoblauch, H., Faulhaber, H.D., Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Uhlmann, R., Tuomilehto, J., Kaprio, J., Jedrusik, P., Januszewicz, A., Strelau, J., Schuster, H., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Mueller-Myhsok, B.
Nature Genetics 26
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1 December 2000
Severely impaired baroreflex-buffering in patients with monogenic hypertension and neurovascular contact.
Jordan, J.
ORCID: https://orcid.org/0000-0003-4518-0706, Toka, H.R., Heusser, K., Toka, O., Shannon, J.R., Tank, J., Diedrich, A., Stabroth, C., Stoffels, M., Naraghi, R., Oelkers, W., Schuster, H., Schobel, H.P., Haller, H. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 102
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21 November 2000
AT1 receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor.
Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Homuth, V., Wallukat, G., Kreuzer, J., Park, J.K., Theuer, J., Juepner, A., Gulba, D.C., Mackman, N., Haller, H. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Circulation 101
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23 May 2000
Dynamics of DNA replication factories in living cells.
Leonhardt, H.
ORCID: https://orcid.org/0000-0002-5086-6449, Rahn, H.P.
ORCID: https://orcid.org/0000-0002-5233-3937, Weinzierl, P., Sporbert, A.
ORCID: https://orcid.org/0000-0002-3738-1295, Cremer, T., Zink, D. and Cardoso, M.C.
ORCID: https://orcid.org/0000-0001-8427-8859
Journal of Cell Biology 149
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17 April 2000
A cholesterol-lowering gene maps to chromosome 13q.
Knoblauch, H., Mueller-Myhsok, B., Busjahn, A., Avi, L.B., Bähring, S.
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Coma in a park.
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Lancet 354
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Kalantar-Zadeh, K. and Luft, F.C.
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Annals of Internal Medicine 131
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Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor.
Wallukat, G., Homuth, V., Fischer, T., Lindschau, C.
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1 April 1999
An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D-3.
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Lancet 32
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Families with autosomal dominant brachydactyly type E, short stature, and severe hypertension.
Toka, H.R., Bähring, S.
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Lancet 351
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28 March 1998
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Gollasch, M.
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1 January 1997
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Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
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Gestational diabetes.
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Medical compared with surgical treatment for massive pulmonary embolism.
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Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
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ORCID: https://orcid.org/0000-0001-9010-8119, McMurray, B.J.
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ORCID: https://orcid.org/0000-0003-4288-3828, Löber, U.
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Cardiovascular Research 118
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Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
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ORCID: https://orcid.org/0000-0003-3030-2678 and Kräker, K.
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Diabetologia 64
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Targeted diets for the gut microbiota and the potential cardiovascular effects.
Chiva-Blanch, G.
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ORCID: https://orcid.org/0000-0003-3650-5644
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1 October 2021
Salt transiently inhibits mitochondrial energetics in mononuclear phagocytes.
Geisberger, S.
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ORCID: https://orcid.org/0000-0003-4288-3828, Neubert, P., Willebrand, R., Zasada, C.
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ORCID: https://orcid.org/0000-0001-8756-747X, Krampert, L., Vogl, M., Mähler, A.
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Circulation 144
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13 July 2021
Skin sodium is increased in male patients with multiple sclerosis and related animal models.
Huhn, K.
ORCID: https://orcid.org/0000-0002-6965-2117, Linz, P.
ORCID: https://orcid.org/0000-0002-8232-1443, Pemsel, F., Michalke, B.
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ORCID: https://orcid.org/0000-0002-8740-3106 and Haase, S.
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Proceedings of the National Academy of Sciences of the United States of America 118
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13 July 2021
Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort.
Birukov, A.
ORCID: https://orcid.org/0000-0002-8306-3351, Andersen, L.B.
ORCID: https://orcid.org/0000-0002-3331-7149, Andersen, M.S., Nielsen, J.H., Nielsen, F.g, Kyhl, H.B., Jørgensen, J.S., Grandjean, P., Dechend, R.
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Environment International 151
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Sodium and its manifold impact on our immune system.
Jobin, K., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Jantsch, J. and Kurts, C.
Trends in Immunology 42
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June 2021
Enhanced Ca(2+) signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1h(M1560V/+)).
Seidel, E.
ORCID: https://orcid.org/0000-0003-3334-3950, Schewe, J.
ORCID: https://orcid.org/0000-0002-7691-4533, Zhang, J.
ORCID: https://orcid.org/0000-0003-0049-8032, Dinh, H.A.
ORCID: https://orcid.org/0000-0002-7367-997X, Forslund, S.K.
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ORCID: https://orcid.org/0000-0003-3650-5644, Lifton, R.P., Nottoli, T.
ORCID: https://orcid.org/0000-0002-2218-5590, Stölting, G.
ORCID: https://orcid.org/0000-0002-2339-0545 and Scholl, U.I.
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Proceedings of the National Academy of Sciences of the United States of America 118
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27 April 2021
The gut microbiome in hypertension: recent advances and future perspectives.
Avery, E.G.
ORCID: https://orcid.org/0000-0002-9094-1423, Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Maifeld, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Marko, L.
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ORCID: https://orcid.org/0000-0003-3189-5364, Rosshart, S.P.
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ORCID: https://orcid.org/0000-0003-4285-6993 and Muller, D.N.
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Circulation Research 128
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2 April 2021
Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients.
Maifeld, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Löber, U.
ORCID: https://orcid.org/0000-0001-7468-9531, Avery, E.G.
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ORCID: https://orcid.org/0000-0002-3904-5789, Hohmann, C., Chen, C.Y.
ORCID: https://orcid.org/0000-0003-1765-7132, Cramer, H., Dobos, G., Lesker, T.R., Strowig, T.
ORCID: https://orcid.org/0000-0003-0185-1459, Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Bzdok, D.
ORCID: https://orcid.org/0000-0003-3466-6620, Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Michalsen, A.
ORCID: https://orcid.org/0000-0002-9145-7246, Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644 and Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993
Nature Communications 12
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30 March 2021
Quantifying technical confounders in microbiome studies.
Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Birkner, T.
ORCID: https://orcid.org/0000-0003-2656-2821, Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Löber, U.
ORCID: https://orcid.org/0000-0001-7468-9531, Avery, E.G.
ORCID: https://orcid.org/0000-0002-9094-1423, Mähler, A.
ORCID: https://orcid.org/0000-0002-3904-5789, Weber, D., Kochlik, B., Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Boschmann, M.
ORCID: https://orcid.org/0000-0002-0114-7114, Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575 and Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993
Cardiovascular Research 117
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1 March 2021
Will postnatal renin-angiotensin system blockade improve long-term maternal cardiovascular health after preeclampsia?
Staff, A.C.
ORCID: https://orcid.org/0000-0001-9247-5721 and Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080
Hypertension 76
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December 2020
Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study.
Leistner, D.M.
ORCID: https://orcid.org/0000-0002-4351-420X, Kränkel, N.
ORCID: https://orcid.org/0000-0002-9363-1770, Meteva, D.
ORCID: https://orcid.org/0000-0003-4741-924X, Abdelwahed, Y.S.
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ORCID: https://orcid.org/0000-0003-3917-1934, Skurk, C., Lauten, A., Mochmann, H.C., Fröhlich, G., Rauch-Kröhnert, U., Flores, E.
ORCID: https://orcid.org/0000-0002-5010-3951, Riedel, M.
ORCID: https://orcid.org/0000-0002-1927-7347, Sieronski, L., Kia, S., Strässler, E., Haghikia, A.
ORCID: https://orcid.org/0000-0002-5646-3237, Dirks, F.
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ORCID: https://orcid.org/0000-0003-3650-5644, Volk, H.D.
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European Heart Journal 41
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20 October 2020
Microscopy with undetected photons in the mid-infrared.
Kviatkovsky, I.
ORCID: https://orcid.org/0000-0003-4071-6014, Chrzanowski, H.M.
ORCID: https://orcid.org/0000-0001-6881-4842, Avery, E.G.
ORCID: https://orcid.org/0000-0002-9094-1423, Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828 and Ramelow, S.
ORCID: https://orcid.org/0000-0002-7801-4440
Science Advances 6
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14 October 2020
Blood pressure and angiogenic markers in pregnancy: contributors to pregnancy-induced hypertension and offspring cardiovascular risk.
Birukov, A..
ORCID: https://orcid.org/0000-0002-8306-3351, Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, Nielsen, J.H., Kyhl, H.B., Golic, M.
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ORCID: https://orcid.org/0000-0003-3650-5644, Jensen, T.K., Christesen, H.T., Andersen, M.S., Jørgensen, J.S., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Andersen, L.B.
ORCID: https://orcid.org/0000-0002-3331-7149
Hypertension 76
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September 2020
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Ercu, M., Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Schächterle, C., Tsvetkov, D.
ORCID: https://orcid.org/0000-0002-6472-971X, Cui, Y., Maghsodi, S., Bartolomaeus, T.U.P.
ORCID: https://orcid.org/0000-0002-5156-7184, Maass, P.G.
ORCID: https://orcid.org/0000-0002-2742-8301, Zühlke, K., Gregersen, N., Hübner, N.
ORCID: https://orcid.org/0000-0002-1218-6223, Hodge, R., Mühl, A., Pohl, B., Molé-Illas, R., Geelhaar, A., Walter, S., Napieczynska, H.
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ORCID: https://orcid.org/0000-0002-8500-489X, Todiras, M.
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ORCID: https://orcid.org/0000-0003-3650-5644, Gollasch, M.
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ORCID: https://orcid.org/0000-0003-4004-5003
Circulation 142
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14 July 2020
RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738, Foster, D.J., Cunningham, M.W., Bercher, J., Nguyen, T., Shulga-Morskaya, S., Milstein, S., Shaikh, S., Rollins, J., Golic, M.
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ORCID: https://orcid.org/0000-0002-4032-5382, Bendix, I.
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1 June 2020
Blood pressure changes correlate with short-chain fatty acid production potential shifts under a synbiotic intervention.
Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Avery, E.G.
ORCID: https://orcid.org/0000-0002-9094-1423, Bartolomaeus, T.U.P.
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ORCID: https://orcid.org/0000-0003-3189-5364, Kushugulova, A. and Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993
Cardiovascular Research 116
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June 2020
Multiplex analysis of circulating maternal cardiovascular biomarkers comparing preeclampsia subtypes.
Lekva, T., Sugulle, M., Moe, K., Redman, C., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Staff, A.C.
Hypertension 75
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June 2020
Myocardial evaluation of post-preeclamptic women by CMR: is early risk stratification possible?
Birukov, A.
ORCID: https://orcid.org/0000-0002-8306-3351, Wiesemann, S., Golic, M.
ORCID: https://orcid.org/0000-0003-3030-2678, Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Marko, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Rakova, N.
ORCID: https://orcid.org/0000-0002-5397-6715, Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Blaszczyk, E.
ORCID: https://orcid.org/0000-0001-7370-1690, Lim, C., Weiss, S., Kräker, K.
ORCID: https://orcid.org/0000-0002-4032-5382, Haase, N.
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ORCID: https://orcid.org/0000-0001-5469-7366, Jørgensen, J.S., Daub, S., Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, Schulz-Menger, J.
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ORCID: https://orcid.org/0000-0001-6636-3080
JACC: Cardiovascular Imaging 13
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May 2020
The (pro)renin receptor: what's in a name?
Simons, M., Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164 and Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Nature Reviews Nephrology 16
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May 2020
B-cell lymphoma/leukemia 10 and angiotensin II-induced kidney injury.
Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Park, J.K., Henke, N., Rong, S., Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Klamer, S., Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Wilck, N.
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ORCID: https://orcid.org/0000-0003-4285-6993, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
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1 April 2020
EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C.
ORCID: https://orcid.org/0000-0003-3242-1195, Lahmann, I.
ORCID: https://orcid.org/0000-0003-0640-4519, Kunz, S.
ORCID: https://orcid.org/0000-0002-0131-3506, Jonas, W., Melo, A.A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Blüher, M., Olschowski, H., Kompa, J., Brügger, B., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Haucke, V.
ORCID: https://orcid.org/0000-0003-3119-6993, Schürmann, A.
ORCID: https://orcid.org/0000-0002-4113-4377, Birchmeier, C.
ORCID: https://orcid.org/0000-0002-2041-8872 and Daumke, O.
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31 March 2020
Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism.
Duscha, A., Gisevius, B., Hirschberg, S., Yissachar, N., Stangl, G.I., Eilers, E., Bader, V., Haase, S., Kaisler, J., David, C., Schneider, R., Troisi, R., Zent, D., Hegelmaier, T., Dokalis, N., Gerstein, S., Del Mare-Roumani, S., Amidror, S., Staszewski, O., Poschmann, G., Stühler, K., Hirche, F., Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Kempa, S.
ORCID: https://orcid.org/0000-0002-0696-9299, Träger, P., Zaiss, M.M., Holm, J.B., Massa, M.G., Nielsen, H.B., Faissner, A., Lukas, C., Gatermann, S.G., Scholz, M., Przuntek, H., Prinz, M., Forslund, S.K.
ORCID: https://orcid.org/0000-0003-4285-6993, Winklhofer, K.F., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Linker, R.A., Gold, R. and Haghikia, A.
Cell 180
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19 March 2020
Natural compound library screening identifies new molecules for the treatment of cardiac fibrosis and diastolic dysfunction.
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ORCID: https://orcid.org/0000-0003-3650-5644, Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Kaever, V., Bähre, H., Batkai, S., Fiedler, J., Alexander, K.M., Wertheim, B.M., Fisch, S., Liao, R., Diez, J., González, A. and Thum, T.
Circulation 141
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3 March 2020
Statins reverse postpartum cardiovascular dysfunction in a rat model of preeclampsia.
Kräker, K.
ORCID: https://orcid.org/0000-0002-4032-5382, O'Driscoll, J.M., Schütte, T.
ORCID: https://orcid.org/0000-0003-4869-2766, Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, Patey, O., Golic, M.
ORCID: https://orcid.org/0000-0003-3030-2678, Geisberger, S.
ORCID: https://orcid.org/0000-0001-6477-1312, Verlohren, S.
ORCID: https://orcid.org/0000-0003-3507-8636, Birukov, A.
ORCID: https://orcid.org/0000-0002-8306-3351, Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Thilaganathan, B., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080 and Haase, N.
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Hypertension 75
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January 2020
Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
Schewe, J., Seidel, E.
ORCID: https://orcid.org/0000-0003-3334-3950, Forslund, S.
ORCID: https://orcid.org/0000-0003-4285-6993, Marko, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Peters, J., Muller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Fahlke, C., Stölting, G.
ORCID: https://orcid.org/0000-0002-2339-0545 and Scholl, U.
ORCID: https://orcid.org/0000-0002-0309-8045
Nature Communications 10
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14 November 2019
The role of sodium in modulating immune cell function.
Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Markó, L.
ORCID: https://orcid.org/0000-0003-1888-5575, Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828 and Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
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September 2019
The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution.
Taylor, D.M., Aronow, B.J., Tan, K., Bernt, K., Salomonis, N., Greene, C.S., Frolova, A.
ORCID: https://orcid.org/0000-0001-5469-7366, Henrickson, S.E., Wells, A., Pei, L., Jaiswal, J.K., Whitsett, J., Hamilton, K.E., MacParland, S.A., Kelsen, J., Heuckeroth, R.O., Potter, S.S., Vella, L.A., Terry, N.A., Ghanem, L.R., Kennedy, B.C., Helbig, I., Sullivan, K.E., Castelo-Soccio, L., Kreigstein, A., Herse, F.
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Developmental Cell 49
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8 April 2019
Sodium in the microenvironment regulates immune responses and tissue homeostasis.
Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Haase, S., Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149 and Linker, R.A.
Nature Reviews Immunology 19
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April 2019
Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H.
ORCID: https://orcid.org/0000-0003-4288-3828, Balogh, A.
ORCID: https://orcid.org/0000-0001-8756-747X, Yakoub, M., Homann, S., Markó, L.
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12 March 2019
GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis.
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ORCID: https://orcid.org/0000-0001-8309-2112, Humrich, J.Y., Klapa, S., Schinke, S., Schimke, L.F., Marschner, G., Pitann, S., Adler, S., Dechend, R.
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ORCID: https://orcid.org/0000-0003-3650-5644, Braicu, I., Sehouli, J., Schulze-Forster, K., Trippel, T., Scheibenbogen, C., Staff, A., Mertens, P.R., Löbel, M., Mastroianni, J.
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ORCID: https://orcid.org/0000-0002-6139-7334, Fernandez-Cabezudo, M.J., Ochs, H.D., Al-Ramadi, B.K., Lamprecht, P., Mueller, A., Heidecke, H. and Riemekasten, G.
Nature Communications 9
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6 December 2018
SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.
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ORCID: https://orcid.org/0000-0003-2797-1934, Amann, K., Müller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644, Pieske, B.
ORCID: https://orcid.org/0000-0002-6466-5306, Lang, F. and Alesutan, I.
Journal of Clinical Investigation 128
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2 July 2018
Salt-responsive gut commensal modulates T(H)17 axis and disease.
Wilck, N.
ORCID: https://orcid.org/0000-0003-3189-5364, Matus, M.G., Kearney, S.M., Olesen, S.W., Forslund, K.
ORCID: https://orcid.org/0000-0003-4285-6993, Bartolomaeus, H.
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ORCID: https://orcid.org/0000-0002-6472-971X, Klug, L., Costea, P.I., Sunagawa, S., Maier, L., Rakova, N.
ORCID: https://orcid.org/0000-0002-5397-6715, Schatz, V., Neubert, P., Frätzer, C., Krannich, A.
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30 November 2017
Disturbed placental imprinting in preeclampsia leads to altered expression of DLX5, a human-specific early trophoblast marker.
Zadora, J.
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ORCID: https://orcid.org/0000-0002-8626-5418, Herse, F.
ORCID: https://orcid.org/0000-0002-9305-8134, Przybyl, L.
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ORCID: https://orcid.org/0000-0003-3030-2678, Yung, H.W., Huppertz, B., Cartwright, J.E., Whitley, G.S., Johnsen, G.M., Levi, G., Isbruch, A., Schulz, H.
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ORCID: https://orcid.org/0000-0001-6636-3080 and Izsvák, Z.
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1 May 2017
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1 May 2017
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ORCID: https://orcid.org/0000-0001-9777-8879, Haase, N.
ORCID: https://orcid.org/0000-0003-0727-1738, Golic, M.
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ORCID: https://orcid.org/0000-0002-5612-1720, Rintisch, C., Schroeder, A., Neuhofer, W., Hilgers, K., Manzel, A., Schwartz, C., Kleinewietfeld, M.
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2 November 2015
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20 October 2015
New role for the (pro)renin receptor in T cell development.
Geisberger, S.
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ORCID: https://orcid.org/0000-0001-6651-4790, Tellez Ceja, Igor Fabian
ORCID: https://orcid.org/0009-0008-0541-9536, Hu, Xiang
ORCID: https://orcid.org/0009-0007-6992-3056, Gladytz, Thomas
ORCID: https://orcid.org/0000-0003-1072-0098, Krenz, Lisa
ORCID: https://orcid.org/0009-0008-7254-4724, Huebler, Dave
ORCID: https://orcid.org/0009-0008-2437-6703, Endemann, Beate
ORCID: https://orcid.org/0009-0004-4976-4121, Brockmann, Claudia
ORCID: https://orcid.org/0000-0002-4753-3045, Beller, Ebba
ORCID: https://orcid.org/0000-0002-5268-151X, Stachs, Oliver
ORCID: https://orcid.org/0000-0002-1225-5372 and Niendorf, Thoralf
ORCID: https://orcid.org/0000-0001-7584-6527
Advanced Materials 38
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8 June 2026
Degradation of biodegradable orthopedic screws does (not) elevate tissue heating under magnetic resonance imaging: implications for next generation implants.
Berangi, Mostafa
ORCID: https://orcid.org/0000-0003-0807-5886, Waiczies, Helmar
ORCID: https://orcid.org/0000-0001-6651-4790, Saha, Nandita
ORCID: https://orcid.org/0000-0001-8555-2477, Shalikar, Shahriar
ORCID: https://orcid.org/0009-0004-1307-2166, Majd, Mahsa Salimi and Niendorf, Thoralf
ORCID: https://orcid.org/0000-0001-7584-6527
Bioactive Materials 64
: 589-603.
16 May 2026
Prevalence and determinants of sacroiliac joint bone marrow oedema in the general population in Germany: a population-based cross-sectional study.
Bressem, Keno, Torgutalp, Murat, Diekhoff, Torsten, Kougkas, Nikolaos, Xu, Lina, Vahldiek, Janis L., Baraliakos, Xenofon, Haibel, Hildrun, Proft, Fabian, Protopopov, Mikhail, Rios Rodriguez, Valeria, Rademacher, Judith, Hermann, Kay-Geert, Aerts, Hugo J.W.L., Niendorf, Thoralf
ORCID: https://orcid.org/0000-0001-7584-6527, Keil, Thomas, Willich, Stefan N., Pischon, Tobias
ORCID: https://orcid.org/0000-0003-1568-767X, Schlett, Christopher L., Ringhof, Steffen, Weiss, Jakob B., Bamberg, Fabian, Kauczor, Hans-Ulrich, Makowski, Marcus R., Adams, Lisa C., Zhukov, Andrei and Poddubnyy, Denis
Lancet Rheumatology
6 May 2026
(In Press)
Body composition in the general population: whole-body MRI-derived reference curves from over 66 000 individuals.
Jung, Matthias
ORCID: https://orcid.org/0000-0002-1124-4284, Reisert, Marco
ORCID: https://orcid.org/0000-0003-2742-1940, Rieder, Hanna, Rospleszcz, Susanne
ORCID: https://orcid.org/0000-0002-4788-2341, Haueise, Tobias
ORCID: https://orcid.org/0000-0002-1462-7539, Pischon, Tobias
ORCID: https://orcid.org/0000-0003-1568-767X, Niendorf, Thoralf
ORCID: https://orcid.org/0000-0001-7584-6527, Kauczor, Hans-Ulrich, Völzke, Henry, Bülow, Robin
ORCID: https://orcid.org/0000-0003-1884-5784, Russe, Maximilian F.
ORCID: https://orcid.org/0000-0003-3187-2429, Schlett, Christopher L.
ORCID: https://orcid.org/0000-0002-1576-1481, Lu, Michael T.
ORCID: https://orcid.org/0000-0003-4696-9610, Bamberg, Fabian
ORCID: https://orcid.org/0000-0002-7460-3942, Raghu, Vineet K.
ORCID: https://orcid.org/0000-0003-3524-3945 and Weiss, Jakob
Radiology 319
(2): e251939.
May 2026
Associations of MRI-derived paraspinal IMAT and LMM with cardiometabolic risk factors: results from a German cohort.
Ziegelmayer, Sebastian
ORCID: https://orcid.org/0000-0001-8724-4718, Häntze, Hartmut
ORCID: https://orcid.org/0000-0002-6204-571X, Mertens, Christian
ORCID: https://orcid.org/0000-0001-7303-2650, Busch, Felix
ORCID: https://orcid.org/0000-0001-9770-8555, Lemke, Tristan
ORCID: https://orcid.org/0009-0006-4269-142X, Graf, Markus
ORCID: https://orcid.org/0000-0002-4668-0326, Navab, Nassir, Faghihroohi, Shahrooz, Kather, Jakob Nikolas
ORCID: https://orcid.org/0000-0002-3730-5348, Truhn, Daniel
ORCID: https://orcid.org/0000-0002-9605-0728, Kröncke, Thomas
ORCID: https://orcid.org/0000-0003-4889-1036, Lammert, Jacqueline
ORCID: https://orcid.org/0000-0002-0380-574X, Kim, Su Hwan
ORCID: https://orcid.org/0000-0002-5383-2041, Wiestler, Benedikt
ORCID: https://orcid.org/0000-0002-2963-7772, Schulz-Menger, Jeanette
ORCID: https://orcid.org/0000-0003-3100-1092, Peters, Annette
ORCID: https://orcid.org/0000-0001-6645-0985, Völzke, Henry, Bülow, Robin
ORCID: https://orcid.org/0000-0003-1884-5784, Niendorf, Thoralf
ORCID: https://orcid.org/0000-0001-7584-6527, Kauczor, Hans-Ulrich, Nonnenmacher, Tobias, Pischon, Tobias
ORCID: https://orcid.org/0000-0003-1568-767X, Ringhof, Steffen
ORCID: https://orcid.org/0000-0003-1823-1037, Schlett, Christopher L.
ORCID: https://orcid.org/0000-0002-1576-1481, Weiß, Jakob, Bamberg, Fabian
ORCID: https://orcid.org/0000-0002-7460-3942, Streit, Ulrike, Hadamitzky, Martin
ORCID: https://orcid.org/0000-0001-6267-1692, Makowski, Marcus R.
ORCID: https://orcid.org/0000-0002-1922-0826, Adams, Lisa
ORCID: https://orcid.org/0000-0001-5836-4542 and Bressem, Keno
ORCID: https://orcid.org/0000-0001-9249-8624
Radiology 319
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May 2026
Segmenting whole-body MRI and CT for multiorgan anatomic structure delineation.
Häntze, Hartmut, Xu, Lina, Mertens, Christian J., Dorfner, Felix J., Donle, Leonhard, Busch, Felix, Kader, Avan, Ziegelmayer, Sebastian, Bayerl, Nadine, Navab, Nassir, Rueckert, Daniel, Schnabel, Julia, Aerts, Hugo J.W.L., Truhn, Daniel, Bamberg, Fabian, Weiss, Jakob, Schlett, Christopher L., Ringhof, Steffen, Niendorf, Thoralf
ORCID: https://orcid.org/0000-0001-7584-6527, Pischon, Tobias
ORCID: https://orcid.org/0000-0003-1568-767X, Kauczor, Hans-Ulrich, Nonnenmacher, Tobias, Kröncke, Thomas, Völzke, Henry, Schulz-Menger, Jeanette
ORCID: https://orcid.org/0000-0003-3100-1092, Maier-Hein, Klaus, Hering, Alessa, Prokop, Mathias, van Ginneken, Bram, Makowski, Marcus R., Adams, Lisa C. and Bressem, Keno K.
Radiology: Artificial Intelligence 7
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November 2025
Magnetic resonance imaging of renal oxygenation.
Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Gladytz, T.
ORCID: https://orcid.org/0000-0003-1072-0098, Cantow, K.
ORCID: https://orcid.org/0000-0002-3907-6315, Millward, J.M.
ORCID: https://orcid.org/0000-0003-4484-2798, Waiczies, S.
ORCID: https://orcid.org/0000-0002-9916-9572 and Seeliger, E.
ORCID: https://orcid.org/0000-0002-5685-8044
Nature Reviews Nephrology 21
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July 2025
Intermuscular adipose tissue and lean muscle mass assessed with MRI in people with chronic back pain in Germany: a retrospective observational study.
Ziegelmayer, S.
ORCID: https://orcid.org/0000-0001-8724-4718, Häntze, H.
ORCID: https://orcid.org/0000-0002-6204-571X, Mertens, C.
ORCID: https://orcid.org/0000-0001-7303-2650, Busch, F.
ORCID: https://orcid.org/0000-0001-9770-8555, Lemke, T., Kather, J.N., Truhn, D., Kim, S.H., Wiestler, B., Graf, M., Kader, A., Bamberg, F., Schlett, C.L., Weiss, J.B., Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Ringhof, S., Can, E., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Lammert, J.
ORCID: https://orcid.org/0000-0002-0380-574X, Schulze, M., Keil, T., Peters, A.
ORCID: https://orcid.org/0000-0001-6645-0985, Hadamitzky, M., Makowski, M.R., Adams, L. and Bressem, K.
ORCID: https://orcid.org/0000-0001-9249-8624
Lancet Regional Health - Europe 54
: 101323.
July 2025
Deep learning-based body composition analysis from whole-body magnetic resonance imaging to predict all-cause mortality in a large western population.
Jung, M.
ORCID: https://orcid.org/0000-0002-1124-4284, Raghu, V.K.
ORCID: https://orcid.org/0000-0003-3524-3945, Reisert, M., Rieder, H., Rospleszcz, S., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Kauczor, H.U., Völzke, H., Bülow, R., Russe, M.F.
ORCID: https://orcid.org/0000-0003-3187-2429, Schlett, C.L., Lu, M.T., Bamberg, F.
ORCID: https://orcid.org/0000-0002-7460-3942 and Weiss, J.
EBioMedicine 110
: 105467.
December 2024
Analysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort.
Haueise, T.
ORCID: https://orcid.org/0000-0002-1462-7539, Schick, F.
ORCID: https://orcid.org/0000-0002-4231-3406, Stefan, N.
ORCID: https://orcid.org/0000-0002-2186-9595, Schlett, C.L.
ORCID: https://orcid.org/0000-0002-1576-1481, Weiss, J.B., Nattenmüller, J.
ORCID: https://orcid.org/0000-0003-4032-378X, Göbel-Guéniot, K., Norajitra, T., Nonnenmacher, T., Kauczor, H.U., Maier-Hein, K.H.
ORCID: https://orcid.org/0000-0002-6626-2463, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Jöckel, K.H.
ORCID: https://orcid.org/0000-0002-1987-0255, Umutlu, L.
ORCID: https://orcid.org/0000-0001-5215-7171, Peters, A.
ORCID: https://orcid.org/0000-0001-6645-0985, Rospleszcz, S.
ORCID: https://orcid.org/0000-0002-4788-2341, Kröncke, T.
ORCID: https://orcid.org/0000-0003-4889-1036, Hosten, N.
ORCID: https://orcid.org/0000-0002-4149-5666, Völzke, H., Krist, L.
ORCID: https://orcid.org/0000-0002-6089-5163, Willich, S.N., Bamberg, F. and Machann, J.
ORCID: https://orcid.org/0000-0002-4458-5886
Science Advances 9
(19): eadd0433.
12 May 2023
A consensus protocol for functional connectivity analysis in the rat brain.
Grandjean, J., Desrosiers-Gregoire, G., Anckaerts, C., Angeles-Valdez, D., Ayad, F., Barrière, D.A., Blockx, I., Bortel, A., Broadwater, M., Cardoso, B.M., Célestine, M., Chavez-Negrete, J.E., Choi, S., Christiaen, E., Clavijo, P., Colon-Perez, L., Cramer, S., Daniele, T., Dempsey, E., Diao, Y., Doelemeyer, A., Dopfel, D., Dvořáková, L., Falfán-Melgoza, C., Fernandes, F.F., Fowler, C.F., Fuentes-Ibañez, A., Garin, C.M., Gelderman, E., Golden, C.E.M., Guo, C.C G., Henckens, M.J.A.G., Hennessy, L.A., Herman, P., Hofwijks, N., Horien, C., Ionescu, T.M., Jones, J., Kaesser, J., Kim, E., Lambers, H., Lazari, A., Lee, S.H., Lillywhite, A., Liu, Y., Liu, Y.Y., López-Castro, A., López-Gil, X., Ma, Z., MacNicol, E., Madularu, D., Mandino, F., Marciano, S., McAuslan, M.J., McCunn, P., McIntosh, A., Meng, X., Meyer-Baese, L., Missault, S., Moro, F., Naessens, D.M.P., Nava-Gomez, L.J., Nonaka, H., Ortiz, J.J., Paasonen, J., Peeters, L.M., Pereira, M., Perez, P.D., Pompilus, M., Prior, M., Rakhmatullin, R., Reimann, H.M.
ORCID: https://orcid.org/0000-0003-1053-9256, Reinwald, J., Del Rio, R.T., Rivera-Olvera, A., Ruiz-Pérez, D., Russo, G., Rutten, T.J., Ryoke, R., Sack, M., Salvan, P., Sanganahalli, B.G., Schroeter, A., Seewoo, B.J., Selingue, E., Seuwen, A., Shi, B., Sirmpilatze, N., Smith, J.A.B., Smith, C., Sobczak, F., Stenroos, P.J., Straathof, M., Strobelt, S., Sumiyoshi, A., Takahashi, K., Torres-García, M.E, Tudela, R., van den Berg, M., van der Marel, K., van Hout, A.T.B., Vertullo, R., Vidal, B., Vrooman, R.M., Wang, V.X., Wank, I., Watson, D.J.G., Yin, T., Zhang, Y., Zurbruegg, S., Achard, S., Alcauter, S., Auer, D.P., Barbier, E.L., Baudewig, J., Beckmann, C.F., Beckmann, N., Becq, G.J.P.C., Blezer, E.L.A., Bolbos, R., Boretius, S., Bouvard, S., Budinger, E., Buxbaum, J.D., Cash, D., Chapman, V., Chuang, K.H., Ciobanu, L., Coolen, B.F., Dalley, J.W., Dhenain, M., Dijkhuizen, R.M., Esteban, O., Faber, C., Febo, M., Feindel, K.W., Forloni, G., Fouquet, J., Garza-Villarreal, E.A., Gass, N., Glennon, J.C., Gozzi, A., Gröhn, O., Harkin, A., Heerschap, A., Helluy, X., Herfert, K., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, Homberg, J.R., Houwing, D.J., Hyder, F., Ielacqua, G.D.
ORCID: https://orcid.org/0000-0002-0816-6617, Jelescu, I.O., Johansen-Berg, H., Kaneko, G., Kawashima, R., Keilholz, S.D., Keliris, G.A., Kelly, C., Kerskens, C., Khokhar, J.Y., Kind, P.C., Langlois, J.B., Lerch, J.P., López-Hidalgo, M.A, Manahan-Vaughan, D., Marchand, F., Mars, R.B., Marsella, G., Micotti, E., Muñoz-Moreno, E., Near, J., Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Otte, W.M., Pais-Roldán, P., Pan, W.J., Prado-Alcalá, R.A., Quirarte, G.L., Rodger, J., Rosenow, T., Sampaio-Baptista, C., Sartorius, A., Sawiak, S.J., Scheenen, T.W.J., Shemesh, N., Shih, Y.Y.I., Shmuel, A., Soria, G., Stoop, R., Thompson, G.J., Till, S.M., Todd, N., Van Der Linden, A., van der Toorn, A., van Tilborg, G.A.F, Vanhove, C., Veltien, A., Verhoye, M., Wachsmuth, L., Weber-Fahr, W., Wenk, P., Yu, X., Zerbi, V., Zhang, N., Zhang, B.B., Zimmer, L., Devenyi, G.A., Chakravarty, M.M. and Hess, A.
Nature Neuroscience 26
(4): 673-681.
April 2023
First in vivo fluorine-19 magnetic resonance imaging of the multiple sclerosis drug siponimod.
Starke, L.
ORCID: https://orcid.org/0000-0002-0359-0101, Millward, J.M.
ORCID: https://orcid.org/0000-0003-4484-2798, Prinz, C.
ORCID: https://orcid.org/0000-0003-3330-031X, Sherazi, F., Waiczies, H.
ORCID: https://orcid.org/0000-0001-6651-4790, Lippert, C.
ORCID: https://orcid.org/0000-0001-6363-2556, Nazaré, M.
ORCID: https://orcid.org/0000-0002-1602-2330, Paul, F.
ORCID: https://orcid.org/0000-0002-6378-0070, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527 and Waiczies, S.
ORCID: https://orcid.org/0000-0002-9916-9572
Theranostics 13
(4): 1217-1234.
5 February 2023
Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging.
Espiritu, J.
ORCID: https://orcid.org/0000-0001-6098-1494, Berangi, M.
ORCID: https://orcid.org/0000-0003-0807-5886, Cwieka, H., Iskhakova, K.
ORCID: https://orcid.org/0000-0002-2499-9774, Kuehne, A.
ORCID: https://orcid.org/0000-0002-4133-5056, Florian Wieland, D.C., Zeller-Plumhoff, B., Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Willumeit-Römer, R. and Seitz, J.M.
Bioactive Materials 25
: 86-94.
23 January 2023
Framework and baseline examination of the German National Cohort (NAKO).
Peters, A.
ORCID: https://orcid.org/0000-0001-6645-0985, Peters, A., Greiser, K.H., Göttlicher, S., Ahrens, W., Albrecht, M., Bamberg, F., Bärnighausen, T., Becher, H., Berger, K., Beule, A., Boeing, H., Bohn, B., Bohnert, K., Braun, B., Brenner, H., Bülow, R., Castell, S., Damms-Machado, A., Dörr, M., Ebert, N., Ecker, M., Emmel, C., Fischer, B., Franzke, C.W., Gastell, S., Giani, G., Günther, M., Günther, K., Günther, K.P., Haerting, J., Haug, U., Heid, I.M., Heier, M., Heinemeyer, D., Hendel, T., Herbolsheimer, F., Hirsch, J., Hoffmann, W., Holleczek, B., Hölling, H., Hörlein, A., Jöckel, K.H., Kaaks, R., Karch, A., Karrasch, S., Kartschmit, N., Kauczor, H.U., Keil, T., Kemmling, Y., Klee, B., Klüppelholz, B., Kluttig, A., Kofink, L., Köttgen, A., Kraft, D., Krause, G., Kretz, L., Krist, L., Kühnisch, J., Kuß, O., Legath, N., Lehnich, A.T., Leitzmann, M., Lieb, W., Linseisen, J., Loeffler, M., Macdonald, A., Maier-Hein, K.H., Mangold, N., Meinke-Franze, C., Meisinger, C., Melzer, J., Mergarten, B., Michels, K.B., Mikolajczyk, R., Moebus, S., Mueller, U., Nauck, M., Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Nikolaou, K., Obi, N., Ostrzinski, S., Panreck, L., Pigeot, I., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Pschibul-Thamm, I., Rathmann, W., Reineke, A., Roloff, S., Rujescu, D., Rupf, S., Sander, O., Schikowski, T., Schipf, S., Schirmacher, P., Schlett, C.L., Schmidt, B., Schmidt, G., Schmidt, M., Schöne, G., Schulz, H., Schulze, M.B., Schweig, A., Sedlmeier, A.M., Selder, S., Six-Merker, J., Sowade, R., Stang, A., Stegle, O., Steindorf, K., Stübs, G., Swart, E., Teismann, H., Thiele, I., Thierry, S., Ueffing, M., Völzke, H., Waniek, S., Weber, A., Werner, N., Wichmann, H.E., Willich, S.N., Wirkner, K., Wolf, K., Wolff, R., Zeeb, H., Zinkhan, M. and Zschocke, J.
European Journal of Epidemiology 37
(10): 1107-1124.
October 2022
Evaluating metallic artefact of biodegradable magnesium-based implants in magnetic resonance imaging.
Espiritu, J., Berangi, M.
ORCID: https://orcid.org/0000-0003-0807-5886, Yiannakou, C., Silva, E., Francischello, R.
ORCID: https://orcid.org/0000-0002-4161-0193, Kuehne, A.
ORCID: https://orcid.org/0000-0002-4133-5056, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Könneker, S., Willumeit-Römer, R.
ORCID: https://orcid.org/0000-0002-6004-6946 and Seitz, J.M.
Bioactive Materials 15
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September 2022
An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
Hahn, T.
ORCID: https://orcid.org/0000-0001-6541-3795, Ernsting, J.
ORCID: https://orcid.org/0000-0003-4649-2111, Winter, N.R.
ORCID: https://orcid.org/0000-0002-6241-1492, Holstein, V., Leenings, R.
ORCID: https://orcid.org/0000-0002-9137-7510, Beisemann, M., Fisch, L.
ORCID: https://orcid.org/0000-0001-6424-7676, Sarink, K.
ORCID: https://orcid.org/0000-0002-4840-5619, Emden, D.
ORCID: https://orcid.org/0000-0001-7459-6634, Opel, N., Redlich, R., Repple, J.
ORCID: https://orcid.org/0000-0003-1379-9491, Grotegerd, D.
ORCID: https://orcid.org/0000-0001-8718-0128, Meinert, S., Hirsch, J.G.
ORCID: https://orcid.org/0000-0003-2341-038X, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Endemann, B.
ORCID: https://orcid.org/0009-0004-4976-4121, Bamberg, F., Kröncke, T.
ORCID: https://orcid.org/0000-0003-4889-1036, Bülow, R.
ORCID: https://orcid.org/0000-0003-1884-5784, Völzke, H., von Stackelberg, O., Sowade, R.F., Umutlu, L., Schmidt, B., Caspers, S., Kugel, H.
ORCID: https://orcid.org/0000-0002-4349-1984, Kircher, T.
ORCID: https://orcid.org/0000-0002-2514-2625, Risse, B., Gaser, C., Cole, J.H.
ORCID: https://orcid.org/0000-0003-1908-5588, Dannlowski, U.
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Science Advances 8
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7 January 2022
In vivo detection of teriflunomide-derived fluorine signal during neuroinflammation using fluorine MR spectroscopy.
Prinz, C.
ORCID: https://orcid.org/0000-0003-3330-031X, Starke, L.
ORCID: https://orcid.org/0000-0002-0359-0101, Millward, J.M.
ORCID: https://orcid.org/0000-0003-4484-2798, Fillmer, A., Delgado, P.R.
ORCID: https://orcid.org/0000-0003-2009-3024, Waiczies, H.
ORCID: https://orcid.org/0000-0001-6651-4790, Pohlmann, A.
ORCID: https://orcid.org/0000-0002-8572-2568, Rothe, M.
ORCID: https://orcid.org/0000-0002-6813-4705, Nazaré, M.
ORCID: https://orcid.org/0000-0002-1602-2330, Paul, F.
ORCID: https://orcid.org/0000-0002-6378-0070, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527 and Waiczies, S.
ORCID: https://orcid.org/0000-0002-9916-9572
Theranostics 11
(6): 2490-2504.
1 January 2021
Brain iron and metabolic abnormalities in C19orf12 mutation carriers: a 7.0 tesla MRI study in mitochondrial membrane protein-associated neurodegeneration.
Dusek, P.
ORCID: https://orcid.org/0000-0003-4877-9642, Mekle, R., Skowronska, M., Acosta-Cabronero, J., Huelnhagen, T.
ORCID: https://orcid.org/0000-0002-6755-2171, Robinson, S.D., Schubert, F., Deschauer, M., Els, A., Ittermann, B., Schottmann, G., Madai, V.I.
ORCID: https://orcid.org/0000-0002-8552-6954, Paul, F.
ORCID: https://orcid.org/0000-0002-6378-0070, Klopstock, T., Kmiec, T., Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Wuerfel, J.
ORCID: https://orcid.org/0000-0002-0034-8053 and Schneider, S.A.
Movement Disorders 35
(1): 142-150.
January 2020
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.
Rathjen, T., Yan, X.
ORCID: https://orcid.org/0000-0002-9135-7915, Kononenko, N.L., Ku, M.C.
ORCID: https://orcid.org/0000-0003-0963-2461, Song, K.
ORCID: https://orcid.org/0000-0001-6216-8157, Ferrarese, L.
ORCID: https://orcid.org/0000-0001-9098-5357, Tarallo, V., Puchkov, D., Kochlamazashvili, G., Brachs, S., Varela, L., Szigeti-Buck, K., Yi, C.X., Schriever, S.C.
ORCID: https://orcid.org/0000-0001-5461-3214, Tattikota, S.G., Carlo, A.S., Moroni, M.
ORCID: https://orcid.org/0000-0002-2389-3468, Siemens, J., Heuser, A.
ORCID: https://orcid.org/0000-0002-3334-960X, van der Weyden, L., Birkenfeld, A.L.
ORCID: https://orcid.org/0000-0003-1407-9023, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Poulet, J.F.A.
ORCID: https://orcid.org/0000-0003-0296-5415, Horvath, T.L., Tschöp, M.H., Heinig, M.
ORCID: https://orcid.org/0000-0002-5612-1720, Trajkovski, M., Haucke, V.
ORCID: https://orcid.org/0000-0003-3119-6993 and Poy, M.N.
ORCID: https://orcid.org/0000-0002-4904-2426
Nature Neuroscience 20
(8): 1096-1103.
August 2017
Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility.
Feutlinske, F., Browarski, M., Ku, M.C.
ORCID: https://orcid.org/0000-0003-0963-2461, Trnka, P., Waiczies, S.
ORCID: https://orcid.org/0000-0002-9916-9572, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Stallcup, W.B., Glass, R., Krause, E. and Maritzen, T.
Nature Communications 6
: 8535.
5 October 2015
Blood oxygen level-dependent magnetic resonance imaging in patients with stress-induced angina.
Friedrich, M.G., Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Schulz-Menger, J.
ORCID: https://orcid.org/0000-0003-3100-1092, Gross, C.M. and Dietz, R.
Circulation 108
(18): 2219-2223.
1 January 2003
Nuernberg, Peter
Functional analysis of complex hepatitis B virus variants associated with development of liver cirrhosis.
Maerschenz, S., Endres, A.S., Brinckmann, A., Heise, T., Kristiansen, G., Nuernberg, P., Krueger, D.H., Guenther, S. and Meisel, H.
Gastroenterology 131
(3): 765-780.
September 2006
A genome-wide scan for attention-deficit/hyperactivity disorder in 155 german sib-pairs.
Hebebrand, J., Dempfle, A., Saar, K., Thiele, H., Herpertz-Dahlmann, B., Linder, M., Kiefl, H., Remschmidt, H., Hemminger, U., Warnke, A., Knoelker, U., Heiser, P., Friedel, S., Hinney, A., Schaefer, H., Nuernberg, P. and Konrad, K.
Molecular Psychiatry 11
(2): 196-205.
February 2006
NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity.
Wojnowski, L., Kulle, B., Schirmer, M., Schlueter, G., Schmidt, A., Rosenberger, A., Vonhof, S., Bickeboeller, H., Toliat, M.R., Suk, E.K., Tzvetkov, M., Kruger, A., Seifert, S., Kloess, M., Hahn, H., Loeffler, M., Nuernberg, P., Pfreundschuh, M., Truemper, L., Brockmoeller, J. and Hasenfuss, G.
Circulation 112
(24): 3754-3762.
5 December 2005
Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.
Schumacher, J., Kaneva, R., Jamra, R.A., Diaz, G.O., Ohlraun, S., Milanova, V., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Rivas, F., Mayoral, F., Fuerst, R., Flaquer, A., Windemuth, C., Gay, E., Sanz, S., Gonzalez, M.J., Gil, S., Cabaleiro, F., del Rio, F., Perez, F., Haro, J., Kostov, C., Chorbov, V., Nikolova-Hill, A., Stoyanova, V., Onchev, G., Kremensky, I., Strauch, K., Schulze, T.G., Nuernberg, P., Gaebel, W., Klimke, A., Auburger, G., Wienker, T.F., Kalaydjieva, L., Propping, P., Cichon, S., Jablensky, A., Rietschel, M. and Noethen, M.M.
American Journal of Human Genetics 77
(6): 1102-1111.
1 December 2005
Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia.
Hillmer, A.M., Hanneken, S., Ritzmann, S., Becker, T., Freudenberg, J., Brockschmidt, F.F., Flaquer, A., Freudenberg-Hua, Y., Jamra, R.A., Metzen, C., Heyn, U., Schweiger, N., Betz, R.C., Blaumeiser, B., Hampe, J., Schreiber, S., Schulze, T.G., Hennies, H.C.
ORCID: https://orcid.org/0000-0001-7210-2389, Schumacher, J., Propping, P., Ruzicka, T., Cichon, S., Wienker, T.F., Kruse, R. and Noethen, M.M.
American Journal of Human Genetics 77
(1): 140-148.
July 2005
Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2.
Metherell, L.A., Chapple, J.P., Cooray, S., David, A., Becker, C., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Naville, D., Begeot, M., Khoo, B., Nuernberg, P., Huebner, A., Cheetham, M.E. and Clark, A.J.L.
Nature Genetics 37
(2): 166-170.
1 January 2005
Mutations in the gene encoding gap junction protein alpha 12 (connexin 46.6) cause Pelizaeus-Merzbacher-like disease.
Uhlenberg, B., Schuelke, M., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Ruf, N., Kaindl, A.M., Henneke, M., Thiele, H., Stoltenburg-Didinger, G., Aksu, F., Topaloglu, H., Nuernberg, P., Huebner, C., Weschke, B. and Gaertner, J.
American Journal of Human Genetics 75
(2): 251-260.
August 2004
Allelic heterogeneity in the COH1 gene explains clinical variability in Cohen syndrome.
Hennies, H.C.
ORCID: https://orcid.org/0000-0001-7210-2389, Rauch, A., Seifert, W., Schumi, C., Moser, E., Al-Taji, E., Tariverdian, G., Chrzanowska, K.H., Krajewska-Walasek, M., Rajab, A., Giugliani, R., Neumann, T.E., Eckl, K.M.
ORCID: https://orcid.org/0000-0001-8838-3998, Karbasiyan, M., Reis, A. and Horn, D.
American Journal of Human Genetics 75
(1): 138-145.
July 2004
Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement.
Thiele, H., Sakano, M., Kitagawa, H., Sugahara, K., Rajab, A., Hoehne, W., Ritter, H., Leschik, G., Nuernberg, P. and Mundlos, S.
Proceedings of the National Academy of Sciences of the United States of America 101
(27): 10155-10160.
23 June 2004
Novel gene locus for autosomal dominant left ventricular noncompaction maps to chromosome 11p15.
Sasse-Klaassen, S.
ORCID: https://orcid.org/0000-0001-5925-9912, Probst, S., Gerull, B.
ORCID: https://orcid.org/0000-0002-1363-8826, Oechslin, E., Nuernberg, P., Heuser, A., Jenni, R., Hennies, H.C.
ORCID: https://orcid.org/0000-0001-7210-2389 and Thierfelder, L.
Circulation 109
(22): 2720-2723.
8 June 2004
Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and mutated in patients affected by autosomal dominant hearing impairment (DFNA4).
Donaudy, F., Snoeckx, R., Pfister, M., Zenner, H.P., Blin, N., Di Stazio, M., Ferrara, A., Lanzara, C., Ficarella, R., Declau, F., Pusch, C.M., Nuernberg, P., Melchionda, S., Zelante, L., Ballana, E., Estivill, X., Van Camp, G., Gasparini, P. and Savoia, A.
American Journal of Human Genetics 74
(4): 770-776.
April 2004
Mutations in RDH12 encoding a photoreceptor cell retinol dehydrogenase cause childhood-onset severe retinal dystrophy.
Janecke, A.R., Thompson, D.A., Utermann, G., Becker, C., Huebner, C.A., Schmid, E., McHenry, C.L., Nair, A.R., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Heckenlively, J., Wissinger, B., Nuernberg, P. and Gal, A.
Nature Genetics 36
(8): 850-854.
1 January 2004
Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2.
Lehmann, K., Seemann, P., Stricker, S., Sammar, M., Meyer, B., Suering, K., Majewski, F., Tinschert, S., Grzeschik, K.H., Mueller, D., Knaus, P., Nuernberg, P. and Mundlos, S.
Proceedings of the National Academy of Sciences of the United States of America 100
(21): 12277-12282.
14 October 2003
Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy.
Geier, C.
ORCID: https://orcid.org/0000-0001-5281-8187, Perrot, A.
ORCID: https://orcid.org/0000-0002-8800-342X, Ozcelik, C., Binner, P., Counsell, D., Hoffmann, K., Pilz, B., Martiniak, Y., Gehmlich, K.
ORCID: https://orcid.org/0000-0003-4019-1844, van der Ven, P.F.M., Furst, D.O., Vornwald, A., von Hodenberg, E., Nuernberg, P., Scheffold, T., Dietz, R. and Osterziel, K.J.
Circulation 107
(10): 1390-1395.
18 March 2003
Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification.
Rutsch, F., Ruf, N., Vaingankar, S., Toliat, M.R., Suk, A., Hoehne, W., Schauer, G., Lehmann, M., Roscioli, T., Schnabel, D., Epplen, J.T., Knisely, A., Superti-Furga, A., McGill, J., Filippone, M., Sinaiko, A.R., Vallance, H., Hinrichs, B., Smith, W., Ferre, M., Terkeltaub, R. and Nuernberg, P.
Nature Genetics 34
(4): 379-381.
1 January 2003
A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution.
Otto, E., Hoefele, J., Ruf, R., Mueller, A.M., Hiller, K.S., Wolf, M.T.F., Schuermann, M.J., Becker, A., Birkenhaeger, R., Sudbrak, R., Hennies, H.C.
ORCID: https://orcid.org/0000-0001-7210-2389, Nuernberg, P. and Hildebrandt, F.
American Journal of Human Genetics 71
(5): 1161-1167.
November 2002
Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huet anomaly).
Hoffmann, K., Dreger, C.K., Olins, A.L., Olins, D.E., Shultz, L.D., Lucke, B., Karl, H., Kaps, R., Mueller, D., Vaya, A., Aznar, J., Ware, R.E., Cruz, N.S., Lindner, T.H., Herrmann, H., Reis, A. and Sperling, K.
Nature Genetics 31
(4): 410-414.
August 2002
Mapping of gene loci for nephronophthisis type 4 and Senior-Loken syndrome, to chromosome 1p36.
Schuermann, M.J., Otto, E., Becker, A., Saar, K., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Polak, B.C., Ala-Mello, S., Hoefele, J., Wiedensohler, A., Haller, M., Omran, H., Nuernberg, P. and Hildebrandt, F.
American Journal of Human Genetics 70
(5): 1240-1246.
May 2002
Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p.
Hampe, J., Frenzel, H., Mirza, M.M., Croucher, P.J., Cuthbert, A., Mascheretti, S., Huse, K., Platzer, M., Bridger, S., Meyer, B., Nuernberg, P., Stokkers, P., Krawczak, M., Mathew, C.G., Curran, M. and Schreiber, S.
Proceedings of the National Academy of Sciences of the United States of America 99
(1): 321-326.
8 January 2002
A comprehensive linkage analysis for myocardial infarction and its related risk factors.
Broeckel, U., Hengstenberg, C., Mayer, B., Holmer, S., Martin, L.J., Comuzzie, A.G., Blangero, J., Nuernberg, P., Reis, A., Riegger, G.A.J., Jacob, H.J. and Schunkert, H.
Nature Genetics 30
: 210-214.
1 January 2002
Mutations in CAV3 cause mechanical hyperirritability of skeletal muscle in rippling muscle disease.
Betz, R.C., Schoser, B.G.H., Kasper, D., Ricker, K., Ramirez, A., Stein, V., Torbergsen, T., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Nothen, M.M., Wienker, T.F., Malin, J.P., Propping, P., Reis, A., Mortier, W., Jentsch, T.J.
ORCID: https://orcid.org/0000-0002-3509-2553, Vorgerd, M. and Kubisch, C.
Nature Genetics 28
(3): 218-219.
July 2001
SPINK1 mutations in chronic pancreatitis.
Witt, H., Hennies, H.C.
ORCID: https://orcid.org/0000-0001-7210-2389 and Becker, M.
Gastroenterology 120
(4): 1060-1061.
March 2001
A novel form of "central pouchlike" cataract, with sutural opacities, maps to chromosome 15q21-22.
Vanita, A., Singh, J.R., Sarhadi, V.K., Singh, D., Reis, A., Rueschendorf, F., Becker-Follmann, J., Jung, M. and Sperling, K.
American Journal of Human Genetics 68
(2): 509-514.
February 2001
Mutations in the gene encoding immunoglobulin mu-binding protein 2 cause spinal muscular atrophy with respiratory distress type 1.
Grohmann, K., Schuelke, M., Diers, A., Hoffmann, K., Lucke, B., Adams, C., Bertini, E., Leonhardt-Horti, H., Muntoni, F., Ouvrier, R., Pfeufer, A., Rossi, R., Van Maldergem, L., Wilmshurst, J.M., Wienker, T.R., Sendtner, M., Rudnik-Schoeneborn, S., Zerres, K. and Huebner, C.
Nature Genetics 29
(1): 75-77.
1 January 2001
Identification, by homozygosity mapping, of a novel locus for autosomal recessive congenital ichthyosis on chromosome 17p, and evidence for further genetic heterogeneity.
Krebsova, A., Kuester, W., Lestringant, G.G., Schulze, B., Hinz, B., Frossard, P.M., Reis, A. and Hennies, H.C.
American Journal of Human Genetics 69
(1): 216-222.
1 January 2001
A second locus for an axonal form of autosomal recessive Charcot-Marie-Tooth disease maps to chromosome 19q13.3.
Leal, A., Morera, B., del Valle, G., Heuss, D., Kayser, C., Berghoff, M., Villegas, R., Hernandez, E., Mendez, M., Hennies, H.C., Neundoerfer, B., Barrantes, R., Reis, A. and Rautenstrauss, B.
American Journal of Human Genetics 68
: 269-274.
1 January 2001
Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia.
Nuernberg, P., Thiele, H., Chandler, D., Hoehne, W., Cunningham, M.L., Ritter, H., Leschik, G., Uhlmann, K., Mischung, C., Harrop, K., Goldblatt, J., Borochowitz, Z.U., Kotzot, D., Westermann, F., Mundlos, S., Braun, H.S., Laing, N. and Tinschert, S.
Nature Genetics 28
(1): 37-41.
1 January 2001
Paternal relatedness and age proximity regulate social relationships among adult female rhesus macaques.
Widdig, A., Nuernberg, P., Krawczak, M., Streich, W.J. and Bercovitch, F.B.
Proceedings of the National Academy of Sciences of the United States of America 98
(24): 13769-13773.
1 January 2001
A major susceptibility locus for atopic dermatitis maps to chromosome 3q21.
Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Wahn, U., Kehrt, R., Tarani, L., Businco, L., Gustafsson, D., Andersson, F., Oranje, A.P., Wolkertstorfer, A., von Berg, A., Hoffmann, U., Kuester, W., Wienker, T.F., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X and Reis, A.
Nature Genetics 26
: 470-473.
1 December 2000
Splitting schizophrenia: Periodic catatonia-susceptibility locus on chromosome 15q15.
Stoeber, G., Saar, K., Rueschendorf, F., Meyer, J., Nuernberg, G., Jatzke, S., Franzek, E., Reis, A., Lesch, K.P., Wienker, T.F. and Beckmann, H.
American Journal of Human Genetics 67
: 1201-1207.
1 November 2000
Genomewide scan in German families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13.
Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Windemuth, C., Schmitt-Egenolf, M., Stadelmann, A., Nuernberg, G., Staender, M., Wienker, T.F., Reis, A. and Traupe, H.
American Journal of Human Genetics 67
(4): 1020-1024.
1 October 2000
Localization of a gene for syndactyly type 1 to chromosome 2q34-q36.
Bosse, K., Betz, R.C., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Wienker, T.F., Reis, A., Kleen, H., Propping, P., Cichon, S. and Noethen, M.M.
American Journal of Human Genetics 67
: 492-497.
1 August 2000
Genome-wide, large-scale production of mutant mice by ENU mutagenesis.
de Angelis, M.H., Flaswinkel, H., Fuchs, H., Rathkolb, B., Soewarto, D., Marschall, S., Heffner, S., Pargent, W., Wuensch, K., Jung, M., Reis, A., Richter, T., Alessandrini, F., Jakob, T., Fuchs, E., Kolb, H., Kremmer, E., Schaeble, K., Rollinski, B., Roscher, A., Peters, C., Meitinger, T., Strom, T., Steckler, T., Holsboer, F., Klopstock, T., Gekeler, F., Schindewolf, C., Jung, T., Avraham, K., Behrendt, H., Ring, J., Zimmer, A., Schughart, K., Pfeffer, K., Wolf, E. and Balling, R.
Nature Genetics 25
: 444-447.
1 August 2000
A gene for hypotrichosis simplex of the scalp maps to chromosome 6p21.3.
Betz, R.C., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Bygum, A., Brandrup, F., Bernal, A.I., Toribio, J., Alvarez, J.I., Kukuk, G.M., Ibsen, H.H.W., Rasmussen, H.B., Wienker, T.F., Reis, A., Propping, P., Kruse, R., Cichon, S. and Noethen, M.M.
American Journal of Human Genetics 66
: 1979-1983.
1 June 2000
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis.
Witt, H., Luck, W., Hennies, H.C., Classen, M., Kage, A., Lass, U., Landt, O. and Becker, M.
Nature Genetics 25
(2): 213-216.
1 June 2000
A gene for an autosomal dominant scleroatrophic syndrome predisposing to skin cancer (Huriez Syndrome) maps to chromosome 4q23.
Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Stevens, H.P., Delaporte, E., Wahn, U. and Reis, A.
American Journal of Human Genetics 66
: 326-330.
1 January 2000
Identification of a new gene locus for adolescent nephronophthisis, on chromosome 3q22 in a large venezuelan pedigree.
Omran, H., Fernandez, C., Jung, M., Haeffner, K., Fargier, B., Villaquiran, A., Waldherr, R., Gretz, N., Brandis, M., Rueschendorf, F., Reis, A. and Hildebrandt, F.
American Journal of Human Genetics 66
(1): 118-127.
1 January 2000
Homozygosity mapping in families with Joubert syndrome identifies a locus on chromosome 9q34.3 and evidence for genetic heterogeneity.
Saar, K., Al-Gazali, L., Sztriha, L., Rueschendorf, F., Nur-E-Kamal, M., Reis, A. and Bayoumi, R.
American Journal of Human Genetics 65
: 1666-1671.
1 December 1999
Diaphragmatic spinal muscular atrophy with respiratory distress is heterogeneous, and one form is linked to chromosome 11q13-q21.
Grohmann, K., Wienker, T.F., Saar, K., Rudnik-Schoeneborn, S., Stoltenburg-Didinger, G., Rossi, R., Novelli, G., Nuernberg, G., Pfeufer, A., Wirth, B., Reis, A., Zerres, K. and Huebner, C.
American Journal of Human Genetics 65
: 1459-1462.
1 November 1999
Dysferlin deletion in SJL mice (SJL-Dysf) defines a natural model for limb girdle muscular dystrophy 2B.
Bittner, R.E., Anderson, L.V.B., Burkhardt, E., Bashir, R., Vafiadaki, E., Ivanova, S., Raffelsberger, T., Maerk, I., Hoeger, H., Jung, M., Karbasiyan, M., Storch, M., Lassmann, H., Moss, J.A., Davison, K., Harrison, R., Bushby, K.M.D. and Reis, A.
Nature Genetics 23
: 141-142.
1 October 1999
Investigation of a family with autosomal dominant dilated cardiomyopathy defines a novel locus on chromosome 2q14-q22.
Jung, M., Poepping, I., Perrot, A.
ORCID: https://orcid.org/0000-0002-8800-342X, Ellmer, A.E., Wienker, T.F., Dietz, R., Reis, A. and Osterziel, K.J.
American Journal of Human Genetics 65
(4): 1068-1077.
October 1999
The Fanconi anemia group E gene, FANCE, maps to chromosome 6p.
Waisfisz, Q., Saar, K., Morgan, N.V., Altay, C., Leegwater, P.A., de Winter, J.P., Komatsu, K., Evans, G.R., Wegner, R.D., Reis, A., Joenje, H., Arwert, F., Mathew, C.G., Pronk, J.C. and Digweed, M.
American Journal of Human Genetics 64
: 1400-1405.
1 May 1999
Limb mammary syndrome: A new genetic disorder with mammary hypoplasia, ectrodactyly, and other hand/foot anomalies maps to human chromosome 3q27.
van Bokhoven, H., Jung, M., Smits, A.P.T., van Beersum, S., Rueschendorf, F., van Steensel, M., Veenstra, M., Tuerlings, J.H.A.M., Mariman, E.C.M., Brunner, H.G., Wienker, T.F., Reis, A., Ropers, H.H. and Hamel, B.C.J.
American Journal of Human Genetics 64
(2): 538-546.
February 1999
Hereditary isolated renal magnesium loss maps to chromosome 11q23.
Meij, I.C.
ORCID: https://orcid.org/0000-0002-8189-2762, Saar, K., van den Heuvel, L.P.W.J., Nuernberg, G., Vollmer, M., Hildebrandt, F., Reis, A., Monnens, L.A.H. and Knoers, N.V.A.M.
American Journal of Human Genetics 64
: 180-188.
1 January 1999
The gene for human fibronectin glomerulopathy maps to 1q32, in the region of the regulation of complement activation gene cluster.
Vollmer, M., Jung, M., Rueschendorf, F., Ruf, R., Wienker, T.F., Reis, A., Krapf, R. and Hildebrandt, F.
American Journal of Human Genetics 63
(6): 1724-1731.
December 1998
Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta 1 subunit gene SCN1B.
Wallace, R.H., Wang, D.W., Singh, R., Scheffer, I.E., George, A.L., Phillips, H.A., Saar, K., Reis, A., Johnson, E.W., Sutherland, G.R., Berkovic, S.F. and Mulley, J.C.
Nature Genetics 19
(4): 366-370.
1 August 1998
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome.
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Brain
26 November 2025
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Targeting formyl peptide receptor 1 reduces brain inflammation and neurodegeneration.
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First in vivo fluorine-19 magnetic resonance imaging of the multiple sclerosis drug siponimod.
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Theranostics 13
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5 February 2023
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt, L.
ORCID: https://orcid.org/0000-0002-7909-020X, Braun, J., Fauchere, F., Vanshylla, K., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Jürchott, K., Mangold, M., Maraj, A., Braginets, A., Böttcher, C.
ORCID: https://orcid.org/0000-0002-6226-586X, Nitsche, A., de la Rosa, K.
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ORCID: https://orcid.org/0000-0002-6378-0070, Bellmann-Strobl, J.
ORCID: https://orcid.org/0000-0003-2615-1643, Thiel, A. and Giesecke-Thiel, C.
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Journal of Neurology Neurosurgery and Psychiatry 93
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In vivo detection of teriflunomide-derived fluorine signal during neuroinflammation using fluorine MR spectroscopy.
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ORCID: https://orcid.org/0000-0003-3330-031X, Starke, L.
ORCID: https://orcid.org/0000-0002-0359-0101, Millward, J.M.
ORCID: https://orcid.org/0000-0003-4484-2798, Fillmer, A., Delgado, P.R.
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ORCID: https://orcid.org/0000-0002-6755-2171, Robinson, S.D., Schubert, F., Deschauer, M., Els, A., Ittermann, B., Schottmann, G., Madai, V.I.
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ORCID: https://orcid.org/0000-0003-2008-3133, Witzel, F., Schmitz, D.
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Nature Communications 10
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Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
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ORCID: https://orcid.org/0000-0001-6941-3397, Hauser, A.E., Pache, F., Meisel, A., Harms, L., Paul, F.
ORCID: https://orcid.org/0000-0002-6378-0070, Dirnagl, U., Garner, C., Schmitz, D.
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Brain 139
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Progressive multiple sclerosis: desperately seeking remedy.
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Peters, Oliver (ECRC)
Minor neuropsychological deficits and stage 2 of Alzheimer's disease.
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ORCID: https://orcid.org/0009-0005-3812-023X, Wagner, Michael, Kuhn, Elizabeth, Roeske, Sandra, Amthauer, Holger, Bartels, Claudia, Boecker, Henning, Brosseron, Frederic, Buchert, Ralph, Buerger, Katharina, Daamen, Marcel, Drzezga, Alexander, Düzel, Emrah, Ersözlü, Ersin, Essler, Markus, Ewers, Michael, Fliessbach, Klaus, Glanz, Wenzel, Hellmann-Regen, Julian
ORCID: https://orcid.org/0000-0003-0411-9204, Incesoy, Enise I., Janowitz, Daniel, Kafali, Konstantinia, Kilimann, Ingo, Krause, Bernd Joachim, Kronmüller, Marie, Laske, Christoph, Maier, Franziska, Maurer, Angelika, Michely, Jochen, Perneczky, Robert, Peters, Oliver
ORCID: https://orcid.org/0000-0003-0568-2998, Preis, Lukas
ORCID: https://orcid.org/0000-0001-7601-6410, Priller, Josef
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Bräuer, Stefan
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ORCID: https://orcid.org/0000-0001-7596-0979, Janowitz, Daniel, Bürger, Katharina, Kilimann, Ingo, Teipel, Stefan, Storch, Alexander, Hansen, Niels, Wiltfang, Jens, Glanz, Wenzel, Düzel, Emrah, Preis, Lukas
ORCID: https://orcid.org/0000-0001-7601-6410, Peters, Oliver
ORCID: https://orcid.org/0000-0003-0568-2998, Hellmann-Regen, Julian
ORCID: https://orcid.org/0000-0003-0411-9204, Wagner, Michael, Bernhardt, Alexander, Levin, Johannes, Petzold, Gabor, Kronmüller, Marie, Gamez, Anna, Spottke, Annika, Brosseron, Frederic, Rostamzadeh, Ayda, Jessen, Frank, Hermann, Andreas, Fliessbach, Klaus, Schneider, Anja and Falkenburger, Björn H.
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An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
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Nature Neuroscience 15
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A CD22-specific T-cell receptor enables effective adoptive T-cell therapy for B-cell malignancies.
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ORCID: https://orcid.org/0000-0001-7857-2461, Grunert, Corinna
ORCID: https://orcid.org/0000-0001-8376-8629, Al-Tabatabaee, Sarah Hayder Jalal, Serin, Nazli, Leisegang, Matthias
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ORCID: https://orcid.org/0000-0002-3381-3003, Freund, Cäcilia
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Safety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part phase Ib/II study.
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Lancet Rheumatology
6 May 2026
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December 2024
Likelihood of post-COVID condition in people with hybrid immunity; data from the German National Cohort (NAKO).
Mikolajczyk, R., Diexer, S., Klee, B., Pfrommer, L., Purschke, O., Fricke, J., Ahnert, P., Gabrysch, S., Gottschick, C., Bohn, B., Brenner, H., Buck, C., Castell, S., Gastell, S., Greiser, K.H., Harth, V., Heise, J.K., Holleczek, B., Kaaks, R., Keil, T., Krist, L., Leitzmann, M., Lieb, W., Meinke-Franze, Cl., Michels, K.B., Moreno Velásquez, I.
ORCID: https://orcid.org/0000-0001-6058-8983, Obi, N., Panreck, L., Peters, A., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Schikowski, T., Schmidt, B., Standl, M., Stang, A., Völzke, H., Weber, A., Zeeb, H. and Karch, A.
Journal of Infection 89
(2): 106206.
August 2024
Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients.
Fislage, M.
ORCID: https://orcid.org/0000-0001-9102-1373, Winzeck, S., Woodrow, R.
ORCID: https://orcid.org/0000-0001-8097-5905, Lammers-Lietz, F.
ORCID: https://orcid.org/0000-0002-7371-3947, Stamatakis, E.A.
ORCID: https://orcid.org/0000-0001-6955-9601, Correia, M.M., Preller, J.
ORCID: https://orcid.org/0000-0001-5706-816X, Feinkohl, I.
ORCID: https://orcid.org/0000-0002-0307-1862, Hendrikse, J., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Spies, C.D.
ORCID: https://orcid.org/0000-0002-1062-0495, Slooter, A.J.C.
ORCID: https://orcid.org/0000-0003-0804-8378, Winterer, G.
ORCID: https://orcid.org/0000-0002-3610-5029, Menon, D.K.
ORCID: https://orcid.org/0000-0002-3228-9692 and Zacharias, N.
ORCID: https://orcid.org/0000-0001-5794-5716
Alzheimer's and Dementia 20
(4): 2861-2872.
April 2024
Analysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort.
Haueise, T.
ORCID: https://orcid.org/0000-0002-1462-7539, Schick, F.
ORCID: https://orcid.org/0000-0002-4231-3406, Stefan, N.
ORCID: https://orcid.org/0000-0002-2186-9595, Schlett, C.L.
ORCID: https://orcid.org/0000-0002-1576-1481, Weiss, J.B., Nattenmüller, J.
ORCID: https://orcid.org/0000-0003-4032-378X, Göbel-Guéniot, K., Norajitra, T., Nonnenmacher, T., Kauczor, H.U., Maier-Hein, K.H.
ORCID: https://orcid.org/0000-0002-6626-2463, Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Jöckel, K.H.
ORCID: https://orcid.org/0000-0002-1987-0255, Umutlu, L.
ORCID: https://orcid.org/0000-0001-5215-7171, Peters, A.
ORCID: https://orcid.org/0000-0001-6645-0985, Rospleszcz, S.
ORCID: https://orcid.org/0000-0002-4788-2341, Kröncke, T.
ORCID: https://orcid.org/0000-0003-4889-1036, Hosten, N.
ORCID: https://orcid.org/0000-0002-4149-5666, Völzke, H., Krist, L.
ORCID: https://orcid.org/0000-0002-6089-5163, Willich, S.N., Bamberg, F. and Machann, J.
ORCID: https://orcid.org/0000-0002-4458-5886
Science Advances 9
(19): eadd0433.
12 May 2023
Framework and baseline examination of the German National Cohort (NAKO).
Peters, A.
ORCID: https://orcid.org/0000-0001-6645-0985, Peters, A., Greiser, K.H., Göttlicher, S., Ahrens, W., Albrecht, M., Bamberg, F., Bärnighausen, T., Becher, H., Berger, K., Beule, A., Boeing, H., Bohn, B., Bohnert, K., Braun, B., Brenner, H., Bülow, R., Castell, S., Damms-Machado, A., Dörr, M., Ebert, N., Ecker, M., Emmel, C., Fischer, B., Franzke, C.W., Gastell, S., Giani, G., Günther, M., Günther, K., Günther, K.P., Haerting, J., Haug, U., Heid, I.M., Heier, M., Heinemeyer, D., Hendel, T., Herbolsheimer, F., Hirsch, J., Hoffmann, W., Holleczek, B., Hölling, H., Hörlein, A., Jöckel, K.H., Kaaks, R., Karch, A., Karrasch, S., Kartschmit, N., Kauczor, H.U., Keil, T., Kemmling, Y., Klee, B., Klüppelholz, B., Kluttig, A., Kofink, L., Köttgen, A., Kraft, D., Krause, G., Kretz, L., Krist, L., Kühnisch, J., Kuß, O., Legath, N., Lehnich, A.T., Leitzmann, M., Lieb, W., Linseisen, J., Loeffler, M., Macdonald, A., Maier-Hein, K.H., Mangold, N., Meinke-Franze, C., Meisinger, C., Melzer, J., Mergarten, B., Michels, K.B., Mikolajczyk, R., Moebus, S., Mueller, U., Nauck, M., Niendorf, T.
ORCID: https://orcid.org/0000-0001-7584-6527, Nikolaou, K., Obi, N., Ostrzinski, S., Panreck, L., Pigeot, I., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Pschibul-Thamm, I., Rathmann, W., Reineke, A., Roloff, S., Rujescu, D., Rupf, S., Sander, O., Schikowski, T., Schipf, S., Schirmacher, P., Schlett, C.L., Schmidt, B., Schmidt, G., Schmidt, M., Schöne, G., Schulz, H., Schulze, M.B., Schweig, A., Sedlmeier, A.M., Selder, S., Six-Merker, J., Sowade, R., Stang, A., Stegle, O., Steindorf, K., Stübs, G., Swart, E., Teismann, H., Thiele, I., Thierry, S., Ueffing, M., Völzke, H., Waniek, S., Weber, A., Werner, N., Wichmann, H.E., Willich, S.N., Wirkner, K., Wolf, K., Wolff, R., Zeeb, H., Zinkhan, M. and Zschocke, J.
European Journal of Epidemiology 37
(10): 1107-1124.
October 2022
The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019.
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Lancet 400
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20 August 2022
Statistical analysis in the German National Cohort (NAKO) - specific aspects and general recommendations.
Kuss, O.
ORCID: https://orcid.org/0000-0003-3301-5869, Becher, H., Wienke, A., Ittermann, T., Ostrzinski, S., Schipf, S., Schmidt, C.O., Leitzmann, M., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Krist, L., Roll, S., Sand, M., Pohlabeln, H., Rach, S., Jöckel, K.H., Stang, A., Mueller, U.A., Werdecker, A., Westerman, R., Greiser, K.H. and Michels, K.B.
European Journal of Epidemiology 37
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April 2022
Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women.
Hur, J.
ORCID: https://orcid.org/0000-0003-0968-208X, Otegbeye, E.
ORCID: https://orcid.org/0000-0001-5403-3615, Joh, H.K., Nimptsch, K.
ORCID: https://orcid.org/0000-0001-7877-205X, Ng, K., Ogino, S.
ORCID: https://orcid.org/0000-0002-3909-2323, Meyerhardt, J.A., Chan, A.T., Willett, W.C., Wu, K., Giovannucci, E.
ORCID: https://orcid.org/0000-0002-6123-0219 and Cao, Y.
ORCID: https://orcid.org/0000-0001-9835-7662
Gut 70
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December 2021
Simple sugar and sugar-sweetened beverage intake during adolescence and risk of colorectal cancer precursors: adolescent sugar intake and colorectal polyp.
Joh, H.K., Lee, D.H., Hur, J., Nimptsch, K.
ORCID: https://orcid.org/0000-0001-7877-205X, Chang, Y., Joung, H., Zhang, X., Rezende, L.F.M., Lee, J.E., Ng, K., Chen, Y., Tabung, F.K., Meyerhardt, J.A., Chan, A.T., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Song, M., Fuchs, C.S., Willett, W.C., Cao, Y., Ogino, S., Giovannucci, E. and Wu, K.
Gastroenterology 161
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July 2021
Methodology of measuring postoperative cognitive dysfunction: a systematic review.
Borchers, F., Spies, C.D., Feinkohl, I.
ORCID: https://orcid.org/0000-0002-0307-1862, Brockhaus, W.R., Kraft, A., Kozma, P., Fislage, M., Kühn, S., Ionescu, C., Speidel, S., Hadzidiakos, D., Veldhuijzen, D.S., Yürek, F., Evered, L.A. and Ottens, T.H.
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Clinical Gastroenterology and Hepatology 18
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March 2020
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Baumeister, S.E., Schlesinger, S.
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May 2019
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
Lancet 392
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2018
Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.
Dimitrakopoulou, V.I., Tsilidis, K.K., Haycock, P.C., Dimou, N.L., Al-Dabhani, K., Martin, R.M., Lewis, S.J., Gunter, M.J., Mondul, A., Shui, I.M., Theodoratou, E., Nimptsch, K.
ORCID: https://orcid.org/0000-0001-7877-205X, Lindstroem, S., Albanes, D., Kuehn, T., Key, T.J., Travis, R.C., Vimaleswaran, K.S., Kraft, P., Pierce, B.L. and Schildkraut, J.M.
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31 October 2017
How to manage the obese patient with cancer.
Renehan, A.G., Harvie, M., Cutress, R.I., Leitzmann, M., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Howell, S. and Howell, A.
Journal of Clinical Oncology 34
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10 December 2016
A prospective study of the immune system activation biomarker neopterin and colorectal cancer risk.
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ORCID: https://orcid.org/0000-0003-1568-767X
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September 2014
Plasma alkylresorcinols, biomarkers of whole-grain wheat and rye intake, and incidence of colorectal cancer.
Kyrø, C, Olsen, A, Landberg, R, Skeie, G, Loft, S, Åman, P, Leenders, M, Dik, VK, Siersema, PD, Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Christensen, J, Overvad, K, Boutron-Ruault, MC, Fagherazzi, G, Cottet, V, Kühn, T, Chang-Claude, J, Boeing, H, Trichopoulou, A, Bamia, C, Trichopoulos, D, Palli, D, Krogh, V, Tumino, R, Vineis, P, Panico, S, Peeters, PH, Weiderpass, E, Bakken, T, Åsli, LA, Argüelles, M, Jakszyn, P, Sánchez, MJ, Amiano, P, Huerta, JM, Barricarte, A, Ljuslinder, I, Palmqvist, R, Khaw, KT, Wareham, N, Key, TJ, Travis, RC, Ferrari, P, Freisling, H, Jenab, M, Gunter, MJ, Murphy, N, Riboli, E, Tjønneland, A and Bueno-de-Mesquita, HB
Journal of the National Cancer Institute 106
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1 January 2014
Novel biomarkers for pre-diabetes identified by metabolomics.
Wang-Sattler, R., Yu, Z., Herder, C., Messias, A.C., Floegel, A., He, Y., Heim, K., Campillos, M., Holzapfel, C., Thorand, B., Grallert, H., Xu, T., Bader, E., Huth, C., Mittelstrass, K., Doering, A., Meisinger, C., Gieger, C., Prehn, C., Roemisch-Margl, W., Carstensen, M., Xie, L., Yamanaka-Okumura, H., Xing, G., Ceglarek, U., Thiery, J., Giani, G., Lickert, H., Lin, X., Li, Y., Boeing, H., Joost, H.G., de Angelis, M.H., Rathmann, W., Suhre, K., Prokisch, H., Peters, A., Meitinger, T., Roden, M., Wichmann, H.E., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Adamski, J. and Illig, T.
Molecular Systems Biology 8
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25 September 2012
Editorial authors' reply to Freedhoff: "Advice to avoid low carbohydrate-high protein diets is not evidence based".
Floegel, A. and Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X
British Medical Journal 345
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6 August 2012
Low carbohydrate-high protein diets.
Floegel, A. and Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X
British Medical Journal 345
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19 June 2012
Hepatocellular carcinoma risk factors and disease burden in a European cohort: a nested case-control study.
Trichopoulos, D., Bamia, C., Lagiou, P., Fedirko, V., Trepo, E., Jenab, M., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X, Noethlings, U., Overved, K., Tjonneland, A., Outzen, M., Clavel-Chapelon, F., Kaaks, R., Lukanova, A., Boeing, H., Aleksandrova, K., Benetou, V., Zylis, D., Palli, D., Pala, V., Panico, S., Tumino, R., Sacerdote, C., Bueno-De-Mesquita, H.B., Van Kranen, H.J., Peeters, P.H., Lund, E., Quiros, J.R., Gonzalez, C.A., Sanchez Perez, M.J., Navarro, C., Dorronsoro, M., Barricarte, A., Lindkvist, B., Regner, S., Werner, M., Hallmans, G., Khaw, K.T., Wareham, N., Key, T., Romieu, I., Chuang, S.C., Murphy, N., Boffetta, P., Trichopoulou, A. and Riboli, E.
Journal of the National Cancer Institute 103
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16 November 2011
Urinary sodium excretion and cardiovascular disease mortality.
Aleksandrova, K., Pischon, T.
ORCID: https://orcid.org/0000-0003-1568-767X and Weikert, C.
JAMA: Journal of the American Medical Association 306
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ORCID: https://orcid.org/0000-0002-1218-448X, Erhardt, Sylvia
ORCID: https://orcid.org/0000-0003-3169-241X, Zaburdaev, Vasily
ORCID: https://orcid.org/0000-0001-8234-3442, Ferrai, Carmelo
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9 June 2026
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An integrated view of the structure and function of the human 4D nucleome.
Dekker, Job, Oksuz, Betul Akgol, Zhang, Yang, Wang, Ye, Minsk, Miriam K., Kuang, Shuzhen, Yang, Liyan, Gibcus, Johan H., Krietenstein, Nils, Rando, Oliver J., Xu, Jie, Janssens, Derek H., Henikoff, Steven, Kukalev, Alexander
ORCID: https://orcid.org/0000-0001-5847-3773, Willemin, Andréa
ORCID: https://orcid.org/0000-0002-4370-6914, Winick-Ng, Warren
ORCID: https://orcid.org/0000-0002-8716-5558, Kempfer, Rieke
ORCID: https://orcid.org/0000-0002-8588-8576, Pombo, Ana
ORCID: https://orcid.org/0000-0002-7493-6288, Yu, Miao, Kumar, Pradeep, Zhang, Liguo, Belmont, Andrew S., Sasaki, Takayo, van Schaik, Tom, Brueckner, Laura, Peric-Hupkes, Daan, van Steensel, Bas, Wang, Ping, Chai, Haoxi, Kim, Minji, Ruan, Yijun, Zhang, Ran, Quinodoz, Sofia A., Bhat, Prashant, Guttman, Mitchell, Zhao, Wenxin, Chien, Shu, Liu, Yuan, Venev, Sergey V., Plewczynski, Dariusz, Irastorza Azcarate, Ibai
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ORCID: https://orcid.org/0000-0002-1566-0971, Szczepińska, Teresa
ORCID: https://orcid.org/0000-0001-9749-1253, Chiliński, Mateusz, Sengupta, Kaustav, Conte, Mattia
ORCID: https://orcid.org/0000-0002-6670-9800, Esposito, Andrea
ORCID: https://orcid.org/0000-0002-5903-8439, Abraham, Alex, Zhang, Ruochi, Wang, Yuchuan, Wen, Xingzhao, Wu, Qiuyang, Yang, Yang, Liu, Jie, Boninsegna, Lorenzo, Yildirim, Asli, Zhan, Yuxiang, Chiariello, Andrea Maria
ORCID: https://orcid.org/0000-0002-6112-0167, Bianco, Simona
ORCID: https://orcid.org/0000-0001-5819-060X, Lee, Lindsay, Hu, Ming, Li, Yun, Barnett, R. Jordan, Cook, Ashley L., Emerson, Daniel J., Marchal, Claire, Zhao, Peiyao, Park, Peter J., Alver, Burak H., Schroeder, Andrew J., Navelkar, Rahi, Bakker, Clara, Ronchetti, William, Ehmsen, Shannon, Veit, Alexander D., Gehlenborg, Nils, Wang, Ting, Li, Daofeng, Wang, Xiaotao, Nicodemi, Mario
ORCID: https://orcid.org/0000-0002-8416-6416, Ren, Bing, Zhong, Sheng, Phillips-Cremins, Jennifer E., Gilbert, David M., Pollard, Katherine S., Alber, Frank, Ma, Jian, Noble, William S. and Yue, Feng
Nature 649
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15 January 2026
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Bolesani, E.
ORCID: https://orcid.org/0000-0002-4237-2705, Bornhorst, D., Iyer, L.I., Zawada, D., Friese, N., Morgan, M., Lange, L., Gonzalez, D., Schrode, N., Leffler, A., Wunder, J., Franke, A., Drakhlis, L., Sebra, R., Schambach, A., Goedel, A., Dubois, N., Dobreva, G.
ORCID: https://orcid.org/0000-0002-4814-9416, Moretti, A., Zelarayán, L.C.
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Patterns and ecological drivers of ocean viral communities.
Brum, J.R., Ignacio-Espinoza, J.C., Roux, S., Doulcier, G., Acinas, S.G., Alberti, A., Chaffron, S., Cruaud, C., de Vargas, C., Gasol, J.M., Gorsky, G., Gregory, A.C., Guidi, L., Hingamp, P., Iudicone, D., Not, F., Ogata, H., Pesant, S., Poulos, B.T., Schwenck, S.M., Speich, S., Dimier, C., Kandels-Lewis, S., Picheral, M., Searson, S., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Bowler, C., Sunagawa, S., Wincker, P., Karsenti, E. and Sullivan, M.B.
Science 348
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22 May 2015
Determinants of community structure in the global plankton interactome.
Lima-Mendez, G., Faust, K., Henry, N., Decelle, J., Colin, S., Carcillo, F., Chaffron, S., Ignacio-Espinosa, J.C., Roux, S., Vincent, F., Bittner, L., Darzi, Y., Wang, J., Audic, S., Berline, L., Bontempi, G., Cabello, A.M., Coppola, L., Cornejo-Castillo, F.M., d' Ovidio, F., De Meester, L., Ferrera, I., Garet-Delmas, M.J., Guidi, L., Lara, E., Pesant, S., Royo-Llonch, M., Salazar, G., Sanchez, P., Sebastian, M., Souffreau, C., Dimier, C., Picheral, M., Searson, S., Kandels-Lewis, S., Gorsky, G., Not, F., Ogata, H., Speich, S., Stemmann, L., Weissenbach, J., Wincker, P., Acinas, S.G., Sunagawa, S., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Sullivan, M.B., Karsenti, E., Bowler, C., de Vargas, C. and Raes, J.
Science 348
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22 May 2015
Structure and function of the global ocean microbiome.
Sunagawa, S., Coelho, L.P., Chaffron, S., Kultima, J.R., Labadie, K., Salazar, G., Djahanschiri, B., Zeller, G., Mende, D.R., Alberti, A., Cornejo-Castillo, F.M., Costea, P.I., Cruaud, C., d'Ovidio, F., Engelen, S., Ferrera, I., Gasol, J.M., Guidi, L., Hildebrand, F., Kokoszka, F., Lepoivre, C., Lima-Mendez, G., Poulain, J., Poulos, B.T., Royo-Llonch, M., Sarmento, H., Vieira-Silva, S., Dimier, C., Picheral, M., Searson, S., Kandels-Lewis, S., Bowler, C., de Vargas, C., Gorsky, G., Grimsley, N., Hingamp, P., Iudicone, D., Jaillon, O., Not, F., Ogata, H., Pesant, S., Speich, S., Stemmann, L., Sullivan, M.B., Weissenbach, J., Wincker, P., Karsenti, E., Raes, J., Acinas, S.G. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Science 348
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22 May 2015
Environmental characteristics of Agulhas rings affect interocean plankton transport.
Villar, E., Farrant, G.K., Follows, M., Garczarek, L., Speich, S., Audic, S., Bittner, L., Blanke, B., Brum, J.R., Brunet, C., Casotti, R., Chase, A., Dolan, J.R., d'Ortenzio, F., Gattuso, J.P., Grima, N., Guidi, L., Hill, C.N., Jahn, O., Jamet, J.L., Le Goff, H., Lepoivre, C., Malviya, S., Pelletier, E., Romagnan, J.B., Roux, S., Santini, S., Scalco, E., Schwenck, S.M., Tanaka, A., Testor, P., Vannier, T., Vincent, F., Zingone, A., Dimier, C., Picheral, M., Searson, S., Kandels-Lewis, S., Acinas, S.G., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Boss, E., de Vargas, C., Gorsky, G., Ogata, H., Pesant, S., Sullivan, M.B., Sunagawa, S., Wincker, P., Karsenti, E., Bowler, C., Not, F., Hingamp, P. and Iudicone, D.
Science 348
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22 May 2015
Eukaryotic plankton diversity in the sunlit ocean.
de Vargas, C., Audic, S., Henry, N., Decelle, J., Mahe, F., Logares, R., Lara, E., Berney, C., Le Bescot, N., Probert, I., Carmichael, M., Poulain, J., Romac, S., Colin, S., Aury, J.M., Bittner, L., Chaffron, S., Dunthorn, M., Engelen, S., Flegontova, O., Guidi, L., Horak, A., Jaillon, O., Lima-Mendez, G., Lukes, J., Malviya, S., Morard, R., Mulot, M., Scalco, E., Siano, R., Vincent, F., Zingone, A., Dimier, C., Picheral, M., Searson, S., Kandels-Lewis, S., Acinas, S.G., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Bowler, C., Gorsky, G., Grimsley, N., Hingamp, P., Iudicone, D., Not, F., Ogata, H., Pesant, S., Raes, J., Sieracki, M.E., Speich, S., Stemmann, L., Sunagawa, S., Weissenbach, J., Wincker, P. and Karsenti, E.
Science 348
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22 May 2015
Computational eco-systems biology in Tara Oceans: translating data into knowledge.
Sunagawa, S., Karsenti, E., Bowler, C. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Molecular Systems Biology 11
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21 May 2015
Temporal and technical variability of human gut metagenomes.
Voigt, A.Y., Costea, P.I., Kultima, J.R., Li, S.S., Zeller, G., Sunagawa, S. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Genome Biology 16
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8 April 2015
Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium.
Lluch-Senar, M., Delgado, J., Chen, W.-H., Llorens-Rico, V., O'Reilly, F.J., Wodke, J.A.H., Unal, E.B., Yus, E., Martinez, S., Nichols, R.J., Ferrar, T., Vivancos, A., Schmeisky, A., Stuelke, J., van Noort, V., Gavin, A.-C., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X and Serrano, L.
Molecular Systems Biology 11
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21 January 2015
Potential of fecal microbiota for early-stage detection of colorectal cancer.
Zeller, G., Tap, J., Voigt, A.Y., Sunagawa, S., Kultima, J.R., Costea, P.I., Amiot, A., Boehm, J., Brunetti, F., Habermann, N., Hercog, R., Koch, M., Luciani, A., Mende, D.R., Schneider, M.A., Schrotz-King, P., Tournigand, C., Tran Van Nhieu, J., Yamada, T., Zimmermann, J., Benes, V., Kloor, M., Ulrich, C.M., von Knebel Doeberitz, M., Sobhani, I. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Molecular Systems Biology 10
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28 November 2014
An integrated catalog of reference genes in the human gut microbiome.
Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J.R., Prifti, E., Nielsen, T., Juncker, A.S., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D., Zhang, Z., Chen, W., Zhao, H., Al-Aama, J.Y., Edris, S., Yang, H., Wang, J., Hansen, T., Nielsen, H.B., Brunak, S., Kristiansen, K., Guarner, F., Pedersen, O., Dore, J., Ehrlich, S.D., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X and Wang, J.
Nature Biotechnology 32
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August 2014
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
Nielsen, H.B., Almeida, M., Juncker, A.S., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D.R., Gautier, L., Pedersen, A.G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J.M., Quintanilha Dos Santos, M.B., Blom, N., Borruel, N., Burgdorf, K.S., Boumezbeur, F., Casellas, F., Dore, J., Dworzynski, P., Guarner, F., Hansen, T., Hildebrand, F., Kaas, R.S., Kennedy, S., Kristiansen, K., Kultima, J.R., Leonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, O., Prifti, E., Qin, J., Raes, J., Sorensen, S., Tap, J., Tims, S., Ussery, D.W., Yamada, T., Renault, P., Sicheritz-Ponten, T., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Wang, J., Brunak, S. and Ehrlich, S.D.
Nature Biotechnology 32
(8): 822-828.
August 2014
Evolution and functional cross-talk of protein post-translational modifications.
Beltrao, P., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Krogan, N.J. and van Noort, V.
Molecular Systems Biology 9
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22 December 2013
Metagenomic species profiling using universal phylogenetic marker genes.
Sunagawa, S., Mende, D.R., Zeller, G., Izquierdo-Carrasco, F., Berger, S.A., Kultima, J.R., Coelho, L.P., Arumugam, M., Tap, J., Nielsen, H.B., Rasmussen, S., Brunak, S., Pedersen, O., Guarner, F., de Vos, W.M., Wang, J., Li, J., Dore, J., Ehrlich, S.D., Stamatakis, A. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature Methods 10
(12): 1196-1199.
December 2013
Accurate and universal delineation of prokaryotic species.
Mende, D.R., Sunagawa, S., Zeller, G. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature Methods 10
(9): 881-884.
September 2013
Genomic variation landscape of the human gut microbiome.
Schloissnig, S., Arumugam, M., Sunagawa, S., Mitreva, M., Tap, J., Zhu, A., Waller, A., Mende, D.R., Kultima, J.R., Martin, J., Kota, K., Sunyaev, S.R., Weinstock, G.M. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature 493
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3 January 2013
Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding.
Iskar, M., Zeller, G., Blattmann, P., Campillos, M., Kuhn, M., Kaminska, K.H., Runz, H., Gavin, A.C., Pepperkok, R., van Noort, V. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Molecular Systems Biology 9
: 662.
2013
Systematic identification of proteins that elicit drug side effects.
Kuhn, M., Al Banchaabouchi, M., Campillos, M., Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X, Gross, C., Gavin, A.C. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Molecular Systems Biology 9
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2013
Deciphering a global network of functionally associated post-translational modifications.
Minguez, P., Parca, L., Diella, F., Mende, D.R., Kumar, R., Helmer-Citterich, M., Gavin, A.C., van Noort, V. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Molecular Systems Biology 8
: 599.
17 July 2012
Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours.
Yamada, T., Waller, A.S., Raes, J., Zelezniak, A., Perchat, N., Perret, A., Salanoubat, M., Patil, K.R., Weissenbach, J. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Molecular Systems Biology 8
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8 May 2012
Enterotypes of the human gut microbiome.
Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D.R., Fernandes, G.R., Tap, J., Bruls, T., Batto, J.M., Bertalan, M., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K., Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H.B., Nielsen, T., Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E.G., Wang, J., Guarner, F., Pedersen, O., de Vos, W.M., Brunak, S., Dore, J., Weissenbach, J., Ehrlich, S.D. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature 473
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12 May 2011
Ontologies in quantitative biology: a basis for comparison, integration, and discovery.
Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
PLoS Biology 8
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25 May 2010
Ageing-related chromatin defects through loss of the NURD complex.
Pegoraro, G., Kubben, N., Wickert, U., Goehler, H., Hoffmann, K. and Misteli, T.
Nature Cell Biology 11
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October 2009
Biochemistry. Not comparable, but complementary.
Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Science 322
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3 October 2008
Drug target identification using side-effect similarity.
Campillos, M., Kuhn, M., Gavin, A.C., Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Science 321
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11 July 2008
The genome of the model beetle and pest tribolium castaneum.
Nature 452
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24 April 2008
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.
Lee-Kirsch, M.A., Gong, M.
ORCID: https://orcid.org/0000-0001-7384-3429, Chowdhury, D., Senenko, L., Engel, K., Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, de Silva, U., Bailey, S.L., Witte, T., Vyse, T.J., Kere, J., Pfeiffer, C., Harvey, S., Wong, A., Koskenmies, S., Hummel, O.
ORCID: https://orcid.org/0009-0000-9986-8333, Rohde, K., Schmidt, R.E., Dominiczak, A.F., Gahr, M., Hollis, T., Perrino, F.W., Lieberman, J. and Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223
Nature Genetics 39
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September 2007
Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis.
Soederhaell, C., Marenholz, I.
ORCID: https://orcid.org/0009-0007-6933-3849, Kerscher, T., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Esparza-Gordillo, J., Worm, M., Gruber, C., Mayr, G., Albrecht, M., Rohde, K., Schulz, H.
ORCID: https://orcid.org/0000-0002-0226-964X, Wahn, U., Huebner, N.
ORCID: https://orcid.org/0000-0002-1218-6223 and Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163
PLoS Biology 5
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September 2007
Systematic discovery of in vivo phosphorylation networks.
Linding, R., Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X, Ostheimer, G.J., van Vugt, M.A., Jorgensen, C., Miron, I.M., Diella, F., Colwill, K., Taylor, L., Elder, K., Metalnikov, P., Nguyen, V., Pasculescu, A., Jin, J., Park, J.G., Samson, L.D., Woodgett, J.R., Russell, R.B., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Yaffe, M.B. and Pawson, T.
Cell 129
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29 June 2007
Insights into social insects from the genome of the honeybee Apis mellifera.
Nature 443
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26 October 2006
Co-evolution of transcriptional and post-translational cell-cycle regulation.
Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X, Jensen, T.S., de Lichtenberg, U., Brunak, S. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature 443
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4 October 2006
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis.
Witt, H., Sahin-Toth, M., Landt, O., Chen, J.M., Kaehne, T., Drenth, J.P., Kukor, Z., Szepessy, E., Halangk, W., Dahm, S., Rohde, K., Schulz, H.U., Le Marechal, C., Akar, N., Ammann, R.W., Truninger, K., Bargetzi, M., Bhatia, E., Castellani, C., Cavestro, G.M., Cerny, M., Destro-Bisol, G., Spedini, G., Eiberg, H., Jansen, J.B., Koudova, M., Rausova, E., Macek, M., Malats, N., Real, F.X., Menzel, H.J., Moral, P., Galavotti, R., Pignatti, P.F., Rickards, O., Spicak, J., Zarnescu, N.O., Boeck, W., Gress, T.M., Friess, H., Ockenga, J., Schmidt, H., Pfuetzer, R., Loehr, M., Simon, P., Weiss, F.U., Lerch, M.M., Teich, N., Keim, V., Berg, T., Wiedenmann, B., Luck, W., Groneberg, D.A., Becker, M., Keil, T., Kage, A., Bernardova, J., Braun, M., Gueldner, C., Halangk, J., Rosendahl, J., Witt, U., Treiber, M., Nickel, R. and Ferec, C.
Nature Genetics 38
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June 2006
Toward automatic reconstruction of a highly resolved tree of life.
Ciccarelli, F.D., Doerks, T., von Mehring, C., Creevey, C.J., Snel, B. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Science 311
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3 March 2006
Literature mining for the biologist: from information retrieval to biological discovery.
Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X, Saric, J. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature Reviews Genetics 7
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February 2006
The effect of single-nucleotide polymorphism marker selection on patterns of haplotype blocks and haplotype frequency estimates.
Nothnagel, M. and Rohde, K.
American Journal of Human Genetics 77
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1 December 2005
Initial sequence of the chimpanzee genome and comparison with the human genome.
Mikkelsen, T.S., Hillier, L.W., Eichler, E.E., Zody, M.C., Jaffe, D.B., Yang, S.P., Enard, W., Hellmann, I., Lindblad-Toh, K., Altheide, T.K., Archidiacono, N., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Butler, J., Chang, J.L., Cheng, Z., Chinwalla, A.T., de Jong, P., Delehaunty, K.D., Fronick, C.C., Fulton, L.L., Gilad, Y., Glusman, G., Gnerre, S., Graves, T.A., Hayakawa, T., Hayden, K.E., Huang, X.Q., Ji, H.K., Kent, W.J., King, M.C., Kulbokas, E.J., Lee, M.K., Liu, G., Lopez-Otin, C., Makova, K.D., Man, O., Mardis, E.R., Mauceli, E., Miner, T.L., Nash, W.E., Nelson, J.O., Paeaebo, S., Patterson, N.J., Pohl, C.S., Pollard, K.S., Pruefer, K., Puente, X.S., Reich, D., Rocchi, M., Rosenbloom, K., Ruvolo, M., Richter, D.J., Schaffner, S.F., Smit, A.F.A., Smith, S.M., Suyama, M., Taylor, J., Torrents, D., Tuzun, E., Varki, A., Velasco, G., Ventura, M., Wallis, J.W., Wendl, M.C., Wilson, R.K., Lander, E.S. and Waterston, R.H.
Nature 437
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1 September 2005
Systematic association of genes to phenotypes by genome and literature mining.
Korbel, J.O., Doerks, T., Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X, Perez-Iratxeta, C., Kaczanowski, S., Hooper, S.D., Andrade, M.A.
ORCID: https://orcid.org/0000-0001-6650-1711 and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
PLoS Biology 3
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5 April 2005
Dynamic complex formation during the yeast cell cycle.
de Lichtenberg, U., Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X, Brunak, S. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Science 307
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4 February 2005
Complex genomic rearrangements lead to novel primate gene function.
Ciccarelli, F.D., von Mering, C.
ORCID: https://orcid.org/0000-0001-7734-9102, Suyama, M., Harrington, E.D., Izaurralde, E. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Genome Research 15
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1 January 2005
Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.
Hillier, L.W., Miller, W., Birney, E., Warren, W., Hardison, R.C., Ponting, C.P., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Burt, D.W., Groenen, M.A.M., Delany, M.E., Dodgson, J.B., Chinwalla, A.T., Cliften, P.F., Clifton, S.W., Delehaunty, K.D., Fronick, C., Fulton, R.S., Graves, T.A., Kremitzki, C., Layman, D., Magrini, V., McPherson, J.D., Miner, T.L., Minx, P., Nash, W.E., Nhan, M.N., Nelson, J.O., Oddy, L.G., Pohl, C.S., Randall-Maher, J., Smith, S.M., Wallis, J.W., Yang, S.P., Romanov, M.N., Rondelli, C.M., Paton, B., Smith, J., Morrice, D., Daniels, L., Tempest, H.G., Robertson, L., Masabanda, J.S., Griffin, D.K., Vignal, A., Fillon, V., Jacobbson, L., Kerje, S., Andersson, L., Crooijmans, R.P.M., Aerts, J., van der Poel, J.J., Ellegren, H., Caldwell, R.B., Hubbard, S.J., Grafham, D.V., Kierzek, A.M., McLaren, S.R., Overton, I.M., Arakawa, H., Beattie, K.J., Bezzubov, Y., Boardman, P.E., Bonfield, J.K., Croning, M.D.R., Davies, R.M., Francis, M.D., Humphray, S.J., Scott, C.E., Taylor, R.G., Tickle, C., Brown, W.R.A., Rogers, J., Buerstedde, J.M., Wilson, S.A., Stubbs, L., Ovcharenko, I., Gordon, L., Lucas, S., Miller, M.M., Inoko, H., Shiina, T., Kaufman, J., Salomonsen, J., Skjoedt, K., Wong, G.K.S., Wang, J., Liu, B., Wang, J., Yu, J., Yang, H.M., Nefedov, M., Koriabine, M., de Jong, P.J., Goodstadt, L., Webber, C., Dickens, N.J., Letunic, I., Suyama, M., Torrents, D., von Mering, C.
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Nature 432
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9 December 2004
Analysis of genomic context: prediction of functional associations from conserved bidirectionally transcribed gene pairs.
Korbel, J.O., Jensen, L.J.
ORCID: https://orcid.org/0000-0001-7885-715X, von Mering, C.
ORCID: https://orcid.org/0000-0001-7734-9102 and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature Biotechnology 22
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1 July 2004
Genome sequence of the Brown Norway rat yields insights into mammalian evolution.
Gibbs, R.A., Weinstock, G.M., Metzker, M.L., Muzny, D.M., Sodergren, E.J., Scherer, S., Scott, G., Steffen, D., Worley, K.C., Burch, P.E., Okwuonu, G., Hines, S., Lewis, L., DeRamo, C., Delgado, O., Dugan-Rocha, S., Miner, G., Morgan, M., Hawes, A., Gill, R., Holt, R.A., Adams, M.D., Amanatides, P.G., Baden-Tillson, H., Barnstead, M., Chin, S., Evans, C.A., Ferriera, S., Fosler, C., Glodek, A., Gu, Z., Jennings, D., Kraft, C.L., Nguyen, T., Pfannkoch, C.M., Sitter, C., Sutton, G.G., Venter, J.C., Woodage, T., Smith, D., Lee, H.M., Gustafson, E., Cahill, P., Kana, A., Doucette-Stamm, L., Weinstock, K., Fechtel, K., Weiss, R.B., Dunn, D.M., Green, E.D., Blakesley, R.W., Bouffard, G.G., de Jong, P.J., Osoegawa, K., Zhu, B., Marra, M., Schein, J., Bosdet, I., Fjell, C., Jones, S., Krzywinski, M., Mathewson, C., Siddiqui, A., Wye, N., McPherson, J., Zhao, S., Fraser, C.M., Shetty, J., Shatsman, S., Geer, K., Chen, Y., Abramzon, S., Nierman, W.C., Havlak, P.H., Chen, R., Durbin, K.J., Egan, A., Ren, Y., Song, X.Z., Li, B., Liu, Y., Qin, X., Cawley, S., Worley, K.C., Cooney, A.J., D'Souza, L.M., Martin, K., Wu, J.Q., Gonzalez-Garay, M.L., Jackson, A.R., Kalafus, K.J., McLeod, M.P., Milosavljevic, A., Virk, D., Volkov, A., Wheeler, D.A., Zhang, Z., Bailey, J.A., Eichler, E.E., Tuzun, E., Birney, E., Mongin, E., Ureta-Vidal, A., Woodwark, C., Zdobnov, E., Bork, P.
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Nature 428
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1 April 2004
A molecular genetic and statistical approach for the diagnosis of dual-site cancers.
Brinkmann, D., Ryan, A., Ayhan, A., McCluggage, W.G., Feakins, R., Santibanez-Koref, M.F., Mein, C.A., Gayther, S.A. and Jacobs, I.J.
Journal of the National Cancer Institute 96
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1 January 2004
Global analysis of bacterial transcription factors to predict cellular target processes.
Doerks, T., Andrade, M.A.
ORCID: https://orcid.org/0000-0001-6650-1711, Lathe, W., von Mering, C.
ORCID: https://orcid.org/0000-0001-7734-9102 and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Trends in Genetics 20
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1 January 2004
Estimating rates of alternative splicing in mammals and invertebrates.
Harrington, E.D., Boue, S., Valcarcel, J., Reich, J.G. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature Genetics 36
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1 January 2004
The HUPO PSI's Molecular Interaction format - a community standard for the representation of protein interaction data.
Hermjakob, H., Montecchi-Palazzi, L., Bader, G., Wojcik, R., Salwinski, L., Ceol, A., Moore, S., Orchard, S., Sarkans, U., von Mering, C.
ORCID: https://orcid.org/0000-0001-7734-9102, Roechert, B., Poux, S., Jung, E., Mersch, H., Kersey, P., Lappe, M., Li, Y.X., Zeng, R., Rana, D., Nikolski, M., Husi, H., Brun, C., Shanker, K., Grant, S.G.N., Sander, C., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Zhu, W.M., Pandey, A., Brazma, A., Jacq, B., Vidal, M., Sherman, D., Legrain, P., Cesareni, G., Xenarios, L., Eisenberg, D., Steipe, B., Hogue, C. and Apweiler, R.
Nature Biotechnology 22
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1 January 2004
The KIND module: a putative signalling domain evolved from the C lobe of the protein kinase fold.
Ciccarelli, F.D., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X and Kerkhoff, E.
Trends in Biochemical Sciences 28
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7 July 2003
Systematic discovery of analogous enzymes in thiamin biosynthesis.
Morett, E., Korbel, J., Rajan, E., Saab-Rincon, G., Olvera, L., Olvera, M., Steffen, S., Snel, B. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature Biotechnology 21
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July 2003
Metabolites: a helping hand for pathway evolution?
Schmidt, S., Sunyaev, S., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X and Dandekar, T.
Trends in Biochemical Sciences 28
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June 2003
Increase of functional diversity by alternative splicing.
Kriventseva, E.V., Koch, I., Apweiler, R., Vingron, M., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X, Gelfand, M.S. and Sunyaev, S.
Trends in Genetics 19
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March 2003
Genome evolution reveals biochemical networks and functional modules.
von Mering, C.
ORCID: https://orcid.org/0000-0001-7734-9102, Zdobnov, E.M., Tsoka, S., Ciccarelli, F.D., Pereira-Leal, J.B., Ouzounis, C.A. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Proceedings of the National Academy of Sciences of the United States of America 100
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1 January 2003
Metabolic network structure determines key aspects of functionality and regulation.
Stelling, J., Klamt, S., Bettenbrock, K., Schuster, S. and Gilles, E.D.
Nature 420
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14 November 2002
Worldwide scientific publishing activity.
Perez-Iratxeta, C. and Andrade, M.A.
ORCID: https://orcid.org/0000-0001-6650-1711
Science 297
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26 July 2002
Association of genes to genetically inherited diseases using data mining.
Perez-Iratxeta, C., Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X and Andrade, M.A.
ORCID: https://orcid.org/0000-0001-6650-1711
Nature Genetics 31
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July 2002
Genome organization: Teamed up for transcription.
von Mering, C.
ORCID: https://orcid.org/0000-0001-7734-9102 and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Nature 417
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20 June 2002
Mapping of gene loci for nephronophthisis type 4 and Senior-Loken syndrome, to chromosome 1p36.
Schuermann, M.J., Otto, E., Becker, A., Saar, K., Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Polak, B.C., Ala-Mello, S., Hoefele, J., Wiedensohler, A., Haller, M., Omran, H., Nuernberg, P. and Hildebrandt, F.
American Journal of Human Genetics 70
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May 2002
Embryonic stem cells - The debate in Germany.
Reich, J.G.
Science 296
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12 April 2002
BSD: a novel domain in transcription factors and synapse-associated proteins.
Doerks, T., Huber, S., Buchner, E. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Trends in Biochemical Sciences 27
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1 April 2002
Integration of genome data and protein structures: prediction of protein folds, protein interactions and 'molecular phenotypes' of single nucleotide polymorphisms (Reprinted from Current Opinion in Structural Biology, vol 11, pg 125-130, 2001).
Sunyaev, S.R., Lathe, W. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Trends in Genetics
(Suppl. March): S19-S24.
March 2002
Alternative splicing and genome complexity.
Brett, D., Pospisil, H., Valcarel, J., Reich, J. and Bork, P.
Nature Genetics 30
(1): 29-30.
1 January 2002
CASH - a beta-helix domain widespread among carbohydrate-binding proteins.
Ciccarelli, F.D., Copley, R.R., Doerks, T., Russell, R.B. and Bork, P.
Trends in Biochemical Sciences 27
(2): 59-62.
1 January 2002
AMOP, a protein module aternativelly spliced in cancer cells.
Ciccarelli, F.D., Doerks, T. and Bork, P.
Trends in Biochemical Sciences 27
: 113-115.
1 January 2002
Inversions and the dynamics of eukaryotic gene order.
Huynen, M.A., Snel, B. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Trends in Genetics 17
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1 June 2001
The draft sequences. Filling in the gaps.
Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X and Copley, R.
Nature 409
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15 February 2001
Initial sequencing and analysis of the human genome.
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Nature 409
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15 February 2001
A novel form of "central pouchlike" cataract, with sutural opacities, maps to chromosome 15q21-22.
Vanita, A., Singh, J.R., Sarhadi, V.K., Singh, D., Reis, A., Rueschendorf, F., Becker-Follmann, J., Jung, M. and Sperling, K.
American Journal of Human Genetics 68
(2): 509-514.
February 2001
DDT - a novel domain in different transcription and chromosome remodeling factors.
Doerks, T., Copley, R. and Bork, P.
Trends in Biochemical Sciences 26
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1 January 2001
XplorMed: a tool for exploring MEDLINE abstracts.
Perez-Iratxeta, C., Bork, P. and Andrade, M.A.
Trends in Biochemical Sciences 26
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1 January 2001
Cooperation and competition in the evolution of ATP-producing pathways.
Pfeiffer, T., Schuster, S. and Bonhoeffer, S.
Science 292
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1 January 2001
Integration of genome data and protein structures: prediction of protein folds, protein interactions and 'molecular phenotypes' of single nucleotide polymorphisms.
Sunyaev, S.R., Lathe, W. and Bork, P.
Current Opinion in Structural Biology 11
(1): 125-130.
1 January 2001
Splitting schizophrenia: Periodic catatonia-susceptibility locus on chromosome 15q15.
Stoeber, G., Saar, K., Rueschendorf, F., Meyer, J., Nuernberg, G., Jatzke, S., Franzek, E., Reis, A., Lesch, K.P., Wienker, T.F. and Beckmann, H.
American Journal of Human Genetics 67
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1 November 2000
GRAM, a novel domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins.
Doerks, T., Strauss, M., Brendel, M. and Bork, P.
Trends in Biochemical Sciences 25
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1 October 2000
Gene context conservation of a higher order than operons.
Lathe, W.C., Snel, B. and Bork, P.
Trends in Biochemical Sciences 25
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1 October 2000
Genomewide scan in German families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13.
Lee, Y.A.
ORCID: https://orcid.org/0000-0002-1817-9163, Rueschendorf, F.
ORCID: https://orcid.org/0000-0001-5640-810X, Windemuth, C., Schmitt-Egenolf, M., Stadelmann, A., Nuernberg, G., Staender, M., Wienker, T.F., Reis, A. and Traupe, H.
American Journal of Human Genetics 67
(4): 1020-1024.
1 October 2000
EST analysis online: WWW tools for detection of SNPs and alternative splice forms.
Brett, D., Lehmann, G., Hanke, J., Gross, S., Reich, J. and Bork, P.
Trends in Genetics 16
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1 September 2000
SNP frequencies in human genes - an excess of rare alleles and differing modes of selection.
Sunyaev, S.R., Lathe, W.C., Ramensky, V.E. and Bork, P.
Trends in Genetics 16
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1 August 2000
L27, a novel heterodimerization domain in receptor targeting proteins Lin-2 and Lin-7.
Doerks, T., Bork, P., Kamberov, E., Makarova, O., Muecke, S. and Margolis, B.
Trends in Biochemical Sciences 25
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1 July 2000
Automated annotation of GPI anchor sites: case study C-elegans.
Eisenhaber, B., Bork, P., Yuan, Y.P., Loeffler, G. and Eisenhaber, F.
Trends in Biochemical Sciences 25
(7): 340-341.
1 July 2000
Sequences and topology. Genome and proteome informatics - Editorial overview.
Bork, P. and Eisenberg, D.
Current Opinion in Structural Biology 10
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1 June 2000
Exploitation of gene context.
Huynen, M.A., Snel, B., Lathe, W. and Bork, P.
Current Opinion in Structural Biology 10
(3): 366-370.
1 June 2000
More than 1,000 putative new human signalling proteins revealed by EST data mining.
Schultz, J., Doerks, T., Ponting, C.P., Copley, R.R. and Bork, P.
Nature Genetics 25
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1 June 2000
Towards a structural basis of human non-synonymous single nucleotide polymorphisms.
Sunyaev, S.R., Ramensky, V. and Bork, P.
Trends in Genetics 16
(5): 198-200.
1 May 2000
A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks.
Schuster, S., Fell, D.A. and Dandekar, T.
Nature Biotechnology 18
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1 March 2000
The GeneQuiz web server: protein functional analysis through the Web.
Hoersch, S., Leroy, C., Brown, N.P., Andrade, M.A.
ORCID: https://orcid.org/0000-0001-6650-1711 and Sander, C.
Trends in Biochemical Sciences 25
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28 January 2000
A cholesterol-lowering gene maps to chromosome 13q.
Knoblauch, H., Mueller-Myhsok, B., Busjahn, A., Avi, L.B., Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Baron, H., Heath, S.C., Uhlmann, R., Faulhaber, H.D., Shpitzen, S., Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Reshef, A., Rosenthal, M., Eliav, O., Muhl, A., Lowe, A., Schurr, D., Harats, D., Jeschke, E., Friedlander, Y., Schuster, H., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Leitersdorf, E.
American Journal of Human Genetics 66
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1 January 2000
Genome evolution - gene fusion versus gene fission.
Snel, B., Bork, P. and Huynen, M.
Trends in Genetics 16
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1 January 2000
Lateral gene transfer, genome surveys, and the phylogeny of prokaryotes.
Huynen, M.A., Snel, B. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Science 286
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19 November 1999
View from the east.
Reich, J.G.
Science 286
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5 November 1999
Alternative splicing of human genes - more the rule than the exception?
Hanke, J., Brett, D., Zastrow, I., Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Delbrueck, S., Lehmann, G., Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199, Reich, J. and Bork, P.
ORCID: https://orcid.org/0000-0002-2627-833X
Trends in Genetics 15
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1 October 1999
Domains in plexins: links to integrins and transcription factors.
Bork, P., Doerks, T., Springer, T.A. and Snel, B.
Trends in Biochemical Sciences 24
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1 July 1999
A novel transactivation domain in parkin.
Morett, E. and Bork, P.
Trends in Biochemical Sciences 24
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1 June 1999
The mahogany protein is a receptor involved in suppression of obesity.
Nagle, D.L., McGrail, S.H., Vitale, J., Wolf, E.A., Dussault, B.J., DiRocco, L., Holmgren, L., Montagno, J., Bork, P., Huszar, D., Fairchild-Huntress, V., Ge, P., Keilty, J., Ebeling, C., Baldini, L., Gilchrist, J., Burn, P., Carlson, G.A. and Moore, K.J.
Nature 398
: 148-152.
11 March 1999
Genome phylogeny based on gene content.
Snel, B., Bork, P. and Huynen, M.A.
Nature Genetics 21
: 108-110.
1 January 1999
Conservation of gene order: a fingerprint of proteins that physically interact.
Dandekar, T., Snel, B., Huynen, M. and Bork, P.
Trends in Biochemical Sciences 23
(9): 324-328.
1 September 1998
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome.
Varon, R., Vissinga, C., Platzer, M., Cerosaletti, K.M., Chrzanowska, K.H., Saar, K., Beckmann, G., Seemanova, E., Cooper, P.R., Nowak, N.J., Stumm, M., Weemaes, C.M.R., Gatti, R.A., Wilson, R.K., Digweed, M., Rosenthal, A., Sperling, K., Concannon, P. and Reis, A.
Cell 93
(3): 467-476.
1 May 1998
Predicting functions from protein sequences - where are the bottlenecks?
Bork, P. and Koonin, E.V.
Nature Genetics 18
: 313-318.
1 January 1998
Protein annotation: detective work for function prediction.
Doerks, T., Bairoch, A. and Bork, P.
Trends in Genetics 14
: 248-250.
1 January 1998
Wanted: subcellular localization of proteins based on sequence.
Eisenhaber, F. and Bork, P.
Trends in Cell Biology 8
: 169-170.
1 January 1998
Gene families: the taxonomy of protein paralogs and chimeras.
Henikoff, S., Greene, E.A., Pietrokovski, S., Bork, P., Attwood, T.K. and Hood, L.
Science 278
(5338): 609-614.
24 October 1997
Localization of the gene causing keratolytic winter erythema to chromosome 8p22-p23, and evidence for a founder effect in south african afrikaans-speakers.
Starfield, M., Hennies, H.C., Jung, M., Jenkins, T., Wienker, T.F., Hull, P., Spurdle, A., Kuester, W., Ramsay, M. and Reis, A.
American Journal of Human Genetics 61
(2): 370-378.
August 1997
A novel class of RanGTP binding proteins.
Goerlich, D., Dabrowski, M., Bischoff, F.R., Kutay, U., Bork, P., Hartmann, E., Prehn, S. and Izaurralde, E.
Journal of Cell Biology 138
(1): 65-80.
14 July 1997
The gene for the ataxia telangiectasia variant, nijmegen breakage syndrome, maps to a 1 cm interval on chromosome 8q21.
Saar, K., Chrzanowska, K.H., Stumm, M., Jung, M., Nuernberg, G., Wienker, T.F., Seemanova, E., Wegner, R.D., Reis, A. and Sperling, K.
American Journal of Human Genetics 60
(3): 605-610.
March 1997
Cytoplasmic signalling domains: the next generation.
Bork, P., Schultz, J. and Ponting, C.P.
Trends in Biochemical Sciences 22
: 296-298.
1 January 1997
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
Bork, P., Hofmann, K., Bucher, P., Neuwald, A., Altschul, S.F. and Koonin, E.V.
FASEB Journal 11
(1): 68-76.
1 January 1997
Deletion at 12p in a japanese child with brachydactyly overlaps the assigned locus of brachydactyly with hypertension in a turkish family.
Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Nagai, T., Toka, H.R., Nitz, I., Toka, O., Aydin, A.
ORCID: https://orcid.org/0000-0002-2890-0225, Muhl, A., Wienker, T.F., Schuster, H. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
American Journal of Human Genetics 60
: 732-735.
1 January 1997
Genome maps 8. Building gene families. Wall chart.
Greene, E.A., Pietrokovski, S., Henikoff, S., Bork, P., Attwood, T.K., Hood, L. and Bairoch, A.
Science 278
: 615-626.
1 January 1997
A putative nucleic acid-binding domain in Werner's and Bloom's syndrome helicases.
Morozov, V., Mushegian, A.R., Koonin, E.V. and Bork, P.
Trends in Biochemical Sciences 22
: 417-418.
1 January 1997
SPRY domains in ryanodine receptors (Ca2+ release channels).
Ponting, C., Schultz, J. and Bork, P.
Trends in Biochemical Sciences 22
: 193-194.
1 January 1997
Analysis of genetic linkage and somatic loss of heterozygosity in affected pairs of first-degree relatives.
Rohde, K., Teare, M.D. and Koref, M.S.
American Journal of Human Genetics 61
: 418-422.
1 January 1997
Secreted fringe like signaling molecules may be glycosyltransferases.
Yuan, Y.P., Schultz, J., Mlodzik, M. and Bork, P.
Cell 88
: 9-11.
1 January 1997
BRCA1 protein products ... Functional motifs...
Koonin, E.V., Altschul, S.F. and Bork, P.
Nature Genetics 13
(3): 266-268.
1 July 1996
Sperm-egg binding protein or proto-oncogene?
Bork, P.
Science 271
(5254): 1431-1432.
1 January 1996
Internal repeats in the BRCA2 protein sequence.
Bork, P., Blomberg, N. and Nilges, M.
Nature Genetics 13
: 22-23.
1 January 1996
Go hunting in sequence databases but watch out for the traps.
Bork, P. and Bairoch, A.
Trends in Genetics 12
: 425-427.
1 January 1996
Friedreich's ataxia protein: phylogenetic evidence for mitochondrial dysfunction.
Gibson, T., Koonin, E.V., Musco, G., Pastore, A. and Bork, P.
Trends in Neurosciences 19
: 465-468.
1 January 1996
Ancient duplication of dna polymerase inferred from analysis of complete bacterial genomes.
Koonin, E.V. and Bork, P.
Trends in Biochemical Sciences 21
(4): 128-129.
1 January 1996
Non-orthologous gene displacement.
Koonin, E.V., Mushegian, A.R. and Bork, P.
Trends in Genetics 12
: 334-336.
1 January 1996
Identification and mutation analysis of the complete gene for the Chediak-Higashi syndrome.
Nagle, D.L., Karim, M., Woolf, E.A., Holmgren, L., Bork, P., Misumi, D., McGrail, D., Dussault, J.R., Duyk, G., Spritz, R.A. and Moore, K.J.
Nature Genetics 14
: 307-312.
1 January 1996
Pleckstrin's repeat performance: a novel domain in g protein signaling.
Ponting, C.P. and Bork, P.
Trends in Biochemical Sciences 21
: 245-246.
1 January 1996
Severe autosomal dominant hypertension and brachydactyly in a unique turkish kindred maps to human chromosome 12.
Schuster, H., Wienker, T.F., Bähring, S.
ORCID: https://orcid.org/0000-0001-8734-9755, Bilginturan, N., Toka, H.R., Neitzel, H., Jeschke, E., Toka, O., Gilbert, D., Lowe, A., Ott, J., Haller, H. and Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199
Nature Genetics 13
(1): 98-100.
1 January 1996
Heat repeats in Huntington's disease protein.
Andrade, M.A. and Bork, P.
Nature Genetics 11
(2): 115-116.
1 October 1995
Polycystic kidney disease: the complete structure of the PKD1 gene and its protein.
Gluecksmann-Kuis, M.A., Tayber, O., Woolf, E.A., Bougueleret, L., Deng, N.H., Alperin, G.D., Iris, F., Hawkins, F., Munro, C., Lakey, N., Duyk, G., Schneider, M.C., Geng, L., Zhang, F., Zhao, Z.H., Torosian, S., Zhou, J., Reeders, S.T., Bork, P., Pohlschmidt, M., Lohning, C., Kraus, B., Nowicka, U., Leung, A.L.S. and Frischauf, A.M.
Cell 81
(2): 289-298.
21 April 1995
A phosphotyrosine interaction domain.
Bork, P. and Margolis, B.
Cell 80
(5): 693-694.
1 January 1995
Challenging times for bioinformatics.
Casari, G., Andrade, M.A., Bork, P., Daruvar, A., Ouzounis, C., Schneider, R., Tamames, J., Valencia, A. and Sander, C.
Nature 376
: 647-648.
1 January 1995
The WW domain: a signalling site in dystrophin.
Bork, P. and Sudol, M.
Trends in Biochemical Sciences 19
(12): 531-533.
1 December 1994
Yeast chromosome III: new gene functions.
Koonin, E., Bork, P. and Sander, C.
EMBO Journal 13
: 493-503.
1 January 1994
An adhesive domain detected in functionally diverse receptors.
Beckmann, G. and Bork, P.
Trends in Biochemical Sciences 18
: 40-41.
1 January 1993
Molecular modelling of the norrie disease protein predicts a cystine knot growth factor tertiary structure.
Meitinger, T., Meindl, A., Bork, P., Rost, B., Sander, C., Haasemann, M. and Murken, J.
Nature Genetics 5
: 376-380.
1 January 1993
Proposed acquisition of an animal protein domain by bacteria.
Bork, P. and Doolittle, R.F.
Proceedings of the National Academy of Sciences of the United States of America 89
: 8990-8994.
1 January 1992
Reszka, Regina
Positron-emission tomography of vector-mediated gene expression in gene therapy for gliomas.
Jacobs, A., Voges, J., Reszka, R., Lercher, M., Gossmann, A., Kracht, L., Kaestle, C., Wagner, R., Wienhard, K. and Heiss, W.D.
Lancet 358
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1 January 2001
S100A1: A regulator of myocardial contractility.
Most, P., Bernotat, J., Ehlermann, P., Pleger, S.T., Reppel, M., Boerries, M., Niroomand, F., Pieske, B., Janssen, P.M.L., Eschenhagen, T., Karczewski, P., Smith, G.L., Koch, W.J.K., Katus, H.A. and Remppis, A.
Proceedings of the National Academy of Sciences of the United States of America 98
(24): 13889-13894.
1 January 2001
Both beta2- and beta1-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling ofbeta2-adrenergic receptors to G(s)-protein.
Molenaar, P., Bartel, S., Cochrane, A., Vetter, D., Jalali, H., Pohlner, P., Burrell, K., Karczewski, P., Krause, E.G. and Kaumann, A.
Circulation 102
(15): 1814-1821.
10 October 2000
Robson, Michael (BIMSB)
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes.
Ringel, A.R.
ORCID: https://orcid.org/0000-0002-6392-6076, Szabo, Q.
ORCID: https://orcid.org/0000-0002-3539-7875, Chiariello, A.M.
ORCID: https://orcid.org/0000-0002-6112-0167, Chudzik, K.
ORCID: https://orcid.org/0000-0002-7606-8381, Schöpflin, R., Rothe, P.
ORCID: https://orcid.org/0000-0003-2366-7775, Mattei, A.L.
ORCID: https://orcid.org/0000-0003-1450-8924, Zehnder, T., Harnett, D.
ORCID: https://orcid.org/0000-0002-9190-128X, Laupert, V., Bianco, S.
ORCID: https://orcid.org/0000-0001-5819-060X, Hetzel, S.
ORCID: https://orcid.org/0000-0002-4783-3814, Glaser, J., Phan, M.H.Q., Schindler, M.
ORCID: https://orcid.org/0000-0003-3363-1864, Ibrahim, D.M.
ORCID: https://orcid.org/0000-0002-0019-3354, Paliou, C., Esposito, A.
ORCID: https://orcid.org/0000-0002-5903-8439, Prada-Medina, C.A., Haas, S.A., Giere, P.
ORCID: https://orcid.org/0000-0002-5570-0085, Vingron, M., Wittler, L.
ORCID: https://orcid.org/0000-0001-7873-6702, Meissner, A., Nicodemi, M.
ORCID: https://orcid.org/0000-0002-8416-6416, Cavalli, G.
ORCID: https://orcid.org/0000-0003-3709-3469, Bantignies, F., Mundlos, S. and Robson, M.I.
ORCID: https://orcid.org/0000-0003-1126-3538
Cell 185
(20): 3689-3704.
29 September 2022
Rocks, Oliver
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Müller, P.M.
ORCID: https://orcid.org/0000-0001-9056-4114, Rademacher, J., Bagshaw, R.D.
ORCID: https://orcid.org/0000-0001-5013-4291, Wortmann, C., Barth, C., van Unen, J., Alp, K.M.
ORCID: https://orcid.org/0000-0001-9919-9838, Giudice, G., Eccles, R.L.
ORCID: https://orcid.org/0000-0002-8209-5650, Heinrich, L.E., Pascual-Vargas, P., Sanchez-Castro, M., Brandenburg, L., Mbamalu, G., Tucholska, M., Spatt, L., Czajkowski, M.T.
ORCID: https://orcid.org/0000-0002-0122-1943, Welke, R.W., Zhang, S., Nguyen, V., Rrustemi, T.
ORCID: https://orcid.org/0000-0002-9075-103X, Trnka, P., Freitag, K.
ORCID: https://orcid.org/0000-0002-5244-3140, Larsen, B., Popp, O.
ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P.
ORCID: https://orcid.org/0000-0002-2245-528X, Gingras, A.C.
ORCID: https://orcid.org/0000-0002-6090-4437, Roth, F.P.
ORCID: https://orcid.org/0000-0002-6628-649X, Colwill, K.
ORCID: https://orcid.org/0000-0002-8979-1659, Bakal, C.
ORCID: https://orcid.org/0000-0002-0413-6744, Pertz, O.
ORCID: https://orcid.org/0000-0001-8579-4919, Pawson, T., Petsalaki, E.
ORCID: https://orcid.org/0000-0002-8294-2995 and Rocks, O.
ORCID: https://orcid.org/0000-0001-6349-9193
Nature Cell Biology 22
(4): 498-511.
April 2020
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A., Roske, Y.
ORCID: https://orcid.org/0000-0001-6237-388X, Barth, C., Lleras Forero, L., Bravo-Rodriguez, K., Redel, Al., Kostova, S.
ORCID: https://orcid.org/0000-0002-6842-6732, McShane, E.
ORCID: https://orcid.org/0000-0002-7806-2063, Opitz, R.
ORCID: https://orcid.org/0000-0003-3143-0997, Faelber, K., Rau, K., Mielke, T., Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414, Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751, Sanchez-Garcia, E., Rocks, O.
ORCID: https://orcid.org/0000-0001-6349-9193, Panáková, D.
ORCID: https://orcid.org/0000-0002-8739-6225, Heinemann, U.
ORCID: https://orcid.org/0000-0002-8191-3850 and Wanker, E.E.
ORCID: https://orcid.org/0000-0001-8072-1630
Nature Communications 7
: 13047.
20 October 2016
Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L.
ORCID: https://orcid.org/0000-0002-8209-5650, Czajkowski, M.T.
ORCID: https://orcid.org/0000-0002-0122-1943, Barth, C., Müller, P.M.
ORCID: https://orcid.org/0000-0001-9056-4114, McShane, E.
ORCID: https://orcid.org/0000-0002-7806-2063, Grunwald, S.
ORCID: https://orcid.org/0000-0003-3978-6277, Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G.
ORCID: https://orcid.org/0000-0003-3647-8623, Selbach, M.
ORCID: https://orcid.org/0000-0003-2454-8751, Hammes, A.
ORCID: https://orcid.org/0000-0003-1663-8378, Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414, Klussmann, E.
ORCID: https://orcid.org/0000-0003-4004-5003, Urbé, S. and Rocks, O.
ORCID: https://orcid.org/0000-0001-6349-9193
Nature Communications 7
: 12963.
7 October 2016
Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein.
Fröhlich, C.
ORCID: https://orcid.org/0000-0002-2930-4097, Grabiger, S., Schwefel, D., Faelber, K., Rosenbaum, E., Mears, J., Rocks, O.
ORCID: https://orcid.org/0000-0001-6349-9193 and Daumke, O.
ORCID: https://orcid.org/0000-0002-6190-1414
EMBO Journal 32
(9): 1280-1292.
2 May 2013
Roetzschke, Olaf
Regulatory T cells ameliorate angiotensin II-induced cardiac damage.
Kvakan, H., Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Qadri, F.
ORCID: https://orcid.org/0000-0002-8500-489X, Park, J.K., Fischer, R.
ORCID: https://orcid.org/0000-0002-4828-2882, Schwarz, I., Rahn, H.P.
ORCID: https://orcid.org/0000-0002-5233-3937, Plehm, R., Wellner, M., Elitok, S., Gratze, P., Dechend, R.
ORCID: https://orcid.org/0000-0001-6636-3080, Luft, F.C.
ORCID: https://orcid.org/0000-0002-8635-1199 and Mueller, D.N.
ORCID: https://orcid.org/0000-0003-3650-5644
Circulation 119
(22): 2904-2912.
9 June 2009
A xenon-129 biosensor for monitoring MHC-peptide interactions.
Schlundt, A., Kilian, W., Beyermann, M., Sticht, J., Guenther, S., Hoepner, S., Falk, K., Roetzschke, O., Mitschang, L. and Freund, C.
Angewandte Chemie International Edition 48
(23): 4142-4145.
25 May 2009
In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.
Roetzschke, O., Borsellino, G., Battistini, L., Falk, K. and Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149
Blood 113
(9): 2119-2120.
26 February 2009
CD49d provides access to 'untouched' human Foxp3+ Treg free of contaminating effector cells.
Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Starke, M., Mitri, D.D., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 113
(4): 827-836.
22 January 2009
Hydrolysis of extracellular ATP by CD39+ Treg cells: context matters!
Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Dimitri, D., Sternjak, A., Diamantini, A., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 111
(2): 965-966.
15 January 2008
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G., Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Di Mitri, D., Sternjak, A., Diamantini, A., Giometto, R., Hoepner, S., Centonze, D., Bernardi, G., Dell'Acqua, M.L., Rossini, P.M., Battistini, L., Roetzschke, O. and Falk, K.
Blood 110
(4): 1225-1232.
15 August 2007
Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.
Bilic, I., Koesters, C., Unger, B., Sekimata, M., Hertweck, A., Maschek, R., Wilson, C.B. and Ellmeier, W.
Nature Immunology 7
(4): 392-400.
April 2006
CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T cell subset.
Kleinewietfeld, M.
ORCID: https://orcid.org/0000-0002-2832-3149, Puentes, F., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 105
(7): 2877-2886.
1 January 2005
A pH-sensitive histidine residue as control element for ligand release from HLA-DR molecules.
Roetzschke, O., Lau, J.M., Hofstätter, M.
ORCID: https://orcid.org/0000-0002-6198-2859, Falk, K. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 99
(26): 16946-16950.
24 December 2002
The final cut: how ERAP1 trims MHC ligands to size.
Falk, K. and Roetzschke, O.
Nature Immunology 3
(12): 1121-1122.
December 2002
Vaccination, prevention, and treatment of experimental autoimmune neuritis (EAN) by an oligomerized T cell epitope.
Stienekemeier, M., Falk, K., Roetzschke, O., Weishaupt, A., Schneider, C., Toyka, K.V., Gold, R. and Strominger, J.L.
Proceedings of the National Academy of Sciences of the United States of America 98
(24): 13872-13877.
1 November 2001
Rosenbauer, Frank
Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils.
Fischer, J.
ORCID: https://orcid.org/0000-0003-3773-9311, Walter, C., Tönges, A., Aleth, H., Costa Jordão, M.J.
ORCID: https://orcid.org/0000-0001-7888-2195, Leddin, M., Gröning, V., Erdmann, T., Lenz, G., Roth, J., Vogl, T., Prinz, M., Dugas, M., Jacobsen, I.D.
ORCID: https://orcid.org/0000-0002-6033-9984 and Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421
Nature Immunology 20
(5): 546-558.
May 2019
Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Staber, P.B., Zhang, P., Ye, M., Welner, R.S., Nombela-Arrieta, C., Bach, C., Kerenyi, M., Bartholdy, B.A., Zhang, H., Alberich-Jorda, M., Lee, S., Yang, H., Ng, F., Zhang, J., Leddin, M., Silberstein, L.E., Hoefler, G., Orkin, S.H., Goettgens, B., Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421, Huang, G. and Tenen, D.G.
Molecular Cell 49
(5): 934-946.
7 March 2013
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, A.M., Vockentanz, L., Kharazi, S., Huska, M.R.
ORCID: https://orcid.org/0000-0002-0912-745X, Mancini, E., Scheller, M., Kuhl, C., Enns, A., Prinz, M., Jaenisch, R., Nerlov, C., Leutz, A.
ORCID: https://orcid.org/0000-0001-8259-927X, Andrade-Navarro, M.A.
ORCID: https://orcid.org/0000-0001-6650-1711, Jacobsen, S.E. and Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421
Nature Genetics 41
(11): 1207-1215.
November 2009
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Ebralidze, A.K., Guibal, F.C., Steidl, U., Zhang, P., Lee, S., Bartholdy, B., Jorda, M.A., Petkova, V., Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421, Huang, G., Dayaram, T., Klupp, J., O'Brien, K.B., Will, B., Hoogenkamp, M., Borden, K.L., Bonifer, C. and Tenen, D.G.
Genes & Development 22
(15): 2085-2092.
1 August 2008
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.
Steidl, U., Steidl, C., Ebralidze, A., Chapuy, B., Han, H.J., Will, B., Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421, Becker, A., Wagner, K., Koschmieder, S., Kobayashi, S., Costa, D.B., Schulz, T., OBrien, K.B., Verhaak, R.G.W., Delwel, R., Haase, D., Truemper, L., Krauter, J., Kohwi-Shigematsu, T., Griesinger, F. and Tenen, D.G.
Journal of Clinical Investigation 117
(9): 2611-2620.
4 September 2007
Transcription factors in myeloid development: balancing differentiation with transformation.
Rosenbauer, F.
ORCID: https://orcid.org/0000-0001-7977-9421 and Tenen, D.G.
Nature Reviews Immunology 7
(2): 105-117.
February 2007
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Circulation 111
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A dual role for lkkalpha in tooth development.
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Developmental Cell 6
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ORCID: https://orcid.org/0000-0002-7582-7171, Butler, Javed, Lam, Carolyn S.P., Vaduganathan, Muthiah, Zannad, Faiez and Borlaug, Barry A.
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Integrated left ventricular multi-omics landscape of human cardiometabolic HFpEF.
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ORCID: https://orcid.org/0000-0001-7775-8352, Fahjen, Pauline
ORCID: https://orcid.org/0000-0002-5015-0643, Strocchi, Stefano
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ORCID: https://orcid.org/0000-0003-0574-8141, Jiang, Yao, Zhou, Ziqin, Zhang, Han, Gillette, Thomas G., Hill, Joseph A., Schiattarella, Gabriele G.
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HFpEF and MASLD: converging mechanisms and clinical implications.
Capone, Federico
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ORCID: https://orcid.org/0000-0002-7582-7171
Nature Reviews Cardiology
23 February 2026
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Beyond BMI: why heart failure trials must quantify adiposity, not just obesity.
Bayes-Genis, Antoni
ORCID: https://orcid.org/0000-0002-3044-197X and Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171
European Journal of Heart Failure
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17 February 2026
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Deep phenotyping of heart failure with preserved ejection fraction through multi-omics integration.
Versnjak, Jakob
ORCID: https://orcid.org/0009-0009-6179-1014, Kuehne, Titus
ORCID: https://orcid.org/0000-0003-1631-4824, Fahjen, Pauline
ORCID: https://orcid.org/0000-0002-5015-0643, Jovanovic, Nina
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European Journal of Heart Failure 27
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December 2025
Pharmacological treatment for patients with obesity and heart failure: focus on glucagon-like peptide-1 receptor agonists. European Journal of Heart Failure expert consensus document.
Monzo, Luca
ORCID: https://orcid.org/0000-0003-2958-943X, Savarese, Gianluigi, Mullens, Wilfried, Abdin, Amr, Bozkurt, Biykem, Chioncel, Ovidiu, El Hadidi, Seif, Gorter, Thomas M., Inciardi, Riccardo M., Petrie, Mark C., Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171, Stolfo, Davide, Metra, Marco and Girerd, Nicolas
European Journal of Heart Failure 27
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November 2025
On the adipokines hypothesis: toward a mechanism-guided reframing of HFpEF.
Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171
Journal of the American College of Cardiology 86
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21 October 2025
Defining HFpEF in rodents: a systematic review.
Adrah, Yamen, Hegemann, Niklas, Faidel, David, Kucherenko, Mariya M., Kuebler, Wolfgang M., Schiattarella, Gabriele G.
ORCID: https://orcid.org/0000-0002-7582-7171, Beyhoff, Niklas
ORCID: https://orcid.org/0000-0001-9140-2336 and Grune, Jana
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Cardiovascular Research 121
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October 2025
Cardiac intermediary metabolism in heart failure: substrate use, signalling roles and therapeutic targets.
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ORCID: https://orcid.org/0000-0001-8361-2448, Heather, Lisa C., Karlstaedt, Anja, Inserte, Javier, Bertrand, Luc
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The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC.
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European Journal of Heart Failure 27
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Cellular and Molecular Immunology 20
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Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury.
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Kidney International 104
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December 2022
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9 September 2022
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Journal for ImmunoTherapy of Cancer 9
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December 2020
Neutrophil gelatinase-associated lipocalin protects from ANCA-induced GN by inhibiting T(H)17 immunity.
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Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast.
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Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system.
Schulze-Topphoff, U., Prat, A., Prozorovski, T., Siffrin, V.
ORCID: https://orcid.org/0000-0002-1532-2868, Paterka, M., Herz, J., Bendix, I.
ORCID: https://orcid.org/0000-0002-9751-3640, Ifergan, I., Schadock, I., Mori, M.A., Van Horssen, J., Schroeter, F., Smorodchenko, A., Han, M.H., Bader, M.
ORCID: https://orcid.org/0000-0003-4780-4164, Steinman, L., Aktas, O.
ORCID: https://orcid.org/0000-0002-2020-9210 and Zipp, F.
ORCID: https://orcid.org/0000-0002-1231-1928
Nature Medicine 15
(7): 788-793.
July 2009
Autoregulation of Th1-mediated inflammation by twist1.
Niesner, U., Albrecht, I., Janke, M., Doebis, C., Loddenkemper, C., Lexberg, M.H., Eulenburg, K., Kreher, S., Koeck, J., Baumgrass, R., Bonhagen, K., Kamradt, T., Enghard, P., Humrich, J.Y., Rutz, S., Schulze-Topphoff, U., Aktas, O.
ORCID: https://orcid.org/0000-0002-2020-9210, Bartfeld, S., Radbruch, H.
ORCID: https://orcid.org/0000-0001-6941-3397, Hegazy, A.N., Lohning, M., Baumgart, D.C., Duchmann, R., Rudwaleit, M., Haupl, T., Gitelman, I., Krenn, V., Gruen, J., Sieper, J., Zeitz, M., Wiedenmann, B., Zipp, F.
ORCID: https://orcid.org/0000-0002-1231-1928, Hamann, A., Janitz, M., Scheffold, A., Burmester, G.R., Chang, H.D. and Radbruch, A.
Journal of Experimental Medicine 205
(8): 1889-1901.
4 August 2008
Treatment-resistant chronic headaches and focal pachymeningitis in a 46-year-old man: a rare presentation of Wegener's granulomatosis.
Doerr, J., Elitok, S., Dieste, F.J., Vogel, H.P., Schneider, W., Wuerfel, J.
ORCID: https://orcid.org/0000-0002-0034-8053, Zipp, F.
ORCID: https://orcid.org/0000-0002-1231-1928 and Paul, F.
Lancet Neurology 7
(4): 368-372.
April 2008
Sirt1 contributes critically to the redox-dependent fate of neural progenitors.
Prozorovski, T., Schulze-Topphoff, U., Glumm, R., Baumgart, J., Schroeter, F., Ninnemann, O., Siegert, E., Bendix, I.
ORCID: https://orcid.org/0000-0002-9751-3640, Bruestle, O., Nitsch, R., Zipp, F.
ORCID: https://orcid.org/0000-0002-1231-1928 and Aktas, O.
ORCID: https://orcid.org/0000-0002-2020-9210
Nature Cell Biology 10
(4): 385-394.
April 2008
TRAIL limits excessive host immune responses in bacterial meningitis.
Hoffmann, O., Priller, J., Prozorovski, T., Schulze-Topphoff, U., Baeva, N., Lunemann, J.D., Aktas, O.
ORCID: https://orcid.org/0000-0002-2020-9210, Mahrhofer, C., Stricker, S., Zipp, F.
ORCID: https://orcid.org/0000-0002-1231-1928 and Weber, J.R.
Journal of Clinical Investigation 117
(7): 2004-2013.
2 July 2007
Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica.
Paul, F., Jarius, S., Aktas, O.
ORCID: https://orcid.org/0000-0002-2020-9210, Bluthner, M., Bauer, O., Appelhans, H., Franciotta, D., Bergamaschi, R., Littleton, E., Palace, J., Seelig, H.P., Hohlfeld, R., Vincent, A. and Zipp, F.
ORCID: https://orcid.org/0000-0002-1231-1928
PLoS Medicine 4
(4): e133.
April 2007
The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases.
Zipp, F.
ORCID: https://orcid.org/0000-0002-1231-1928 and Aktas, O.
ORCID: https://orcid.org/0000-0002-2020-9210
Trends in Neurosciences 29
(9): 518-527.
September 2006
This list was generated on Mon Jun 22 16:07:01 2026 UTC.