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Abdelilah-Seyfried, Salim

Pattern formation in janus-mutant zebrafish embryos.
Abdelilah, S. and Driever, W.
Developmental Biology 184 (1): 70-84. 1 April 1997

Mutations affecting neural survival in the zebrafish Danio rerio.
Abdelilah, S., Mountcastle-Shah, E., Harvey, M., Solnica-Krezel, L., Schier, A.F., Stemple, D.L., Malicki, J., Neuhauss, S.C., Zwartkruis, F., Stainier, D.Y., Rangini, Z. and Driever, W.
Development 123 : 217-227. December 1996

Implications for dorsoventral axis determination from the zebrafish mutation janus.
Abdelilah, S., Solnica-Krezel, L., Stainier, D.Y. and Driever, W.
Nature 370 (6489): 468-471. 11 August 1994

Claudin-5a in developing zebrafish brain barriers: another brick in the wall.
Abdelilah-Seyfried, S.
BioEssays 32 (9): 768-776. September 2010

Morpholino oligonucleotides, functional genomics by gene 'knock-down'.
Abdelilah-Seyfried, S.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1185-1187. ISBN 3-540-44244-8 2006

Bazooka is a permissive factor for the invasive behavior of discs large tumor cells in Drosophila ovarian follicular epithelia.
Abdelilah-Seyfried, S., Cox, D.N. and Jan, Y.N.
Development 130 (9): 1927-1935. 1 May 2003

Elucidation of megalin/LRP2-dependent endocytic transport processes in the larval zebrafish pronephros.
Anzenberger, U., Bit-Avragim, N., Rohr, S., Rudolph, F., Dehmel, B., Willnow, T.E. and Abdelilah-Seyfried, S.
Journal of Cell Science 119 (Pt. 10): 2127-2137. 15 May 2006

Shaping the zebrafish heart: from left-right axis specification to epithelial tissue morphogenesis.
Bakkers, J., Verhoeven, M.C. and Abdelilah-Seyfried, S.
Developmental Biology 330 (2): 213-220. 15 June 2009

Simultaneous Raman microspectroscopy and fluorescence imaging of bone mineralization in living zebrafish larvae.
Bennet, M., Akiva, A., Faivre, D., Malkinson, G., Yaniv, K., Abdelilah-Seyfried, S., Fratzl, P. and Masic, A.
Biophysical Journal 106 (4): L17-L19. 18 February 2014

Divergent polarization mechanisms during vertebrate epithelial development mediated by the Crumbs complex protein Nagie oko.
Bit-Avragim, N., Hellwig, N., Rudolph, F., Munson, C., Stainier, D.Y. and Abdelilah-Seyfried, S.
Journal of Cell Science 121 (Pt 15): 2503-2510. 1 August 2008

Nuclear localization of the zebrafish tight junction protein nagie oko.
Bit-Avragim, N., Rohr, S., Rudolph, F., Van der Ven, P., Furst, D., Eichhorst, J., Wiesner, B. and Abdelilah-Seyfried, S.
Developmental Dynamics 237 (1): 83-90. January 2008

In vivo conditions to identify prkci phosphorylation targets using the analog-sensitive kinase method in zebrafish.
Cibrian Uhalte, E., Kirchner, M., Hellwig, N., Allen, J.J., Donat, S., Shokat, K.M., Selbach, M. and Abdelilah-Seyfried, S.
PLoS ONE 7 (6): e40000. 29 June 2012

Cell polarity.
Cibrian-Uhalte, E. and Abdelilah-Seyfried, S.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 1. Springer, Berlin [u.a.], 237-243. ISBN 3-540-44244-8 2006

Involvement of zebrafish Na+,K+ ATPase in myocardial cell junction maintenance.
Cibrian-Uhalte, E., Langenbacher, A., Shu, X., Chen, J.N. and Abdelilah-Seyfried, S.
Journal of Cell Biology 176 (2): 223-230. 15 January 2007

Analysis of aPKClambda and aPKCzeta reveals multiple and redundant functions during vertebrate retinogenesis.
Cui, S., Otten, C., Rohr, S., Abdelilah-Seyfried, S. and Link, B.A.
Molecular and Cellular Neuroscience 34 (3): 431-444. March 2007

Blood flow and Bmp signaling control endocardial chamber morphogenesis.
Dietrich, A.C., Lombardo, V.A., Veerkamp, J., Priller, F. and Abdelilah-Seyfried, S.
Developmental Cell 30 (4): 367-377. 25 August 2014

Genetic analysis of pattern formation in the zebrafish neural plate.
Driever, W., Solnica-Krezel, L., Abdelilah, S., Meyer, D. and Stemple, D.
Cold Spring Harbor Symposia on Quantitative Biology 62 : 523-34. 1997

A genetic screen for mutations affecting embryogenesis in zebrafish.
Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J. and Boggs, C.
Development 123 : 37-46. December 1996

Genie: literature-based gene prioritization at multi genomic scale.
Fontaine, J.F., Priller, F., Barbosa-Silva, A. and Andrade-Navarro, M.A.
Nucleic Acids Research 39 (Suppl 2): W455-W461. July 2011

Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S., Riemke, P., Schoenheit, J., Lenze, D., Stumm, J., Hoogenkamp, M., Lagendijk, A., Heinz, S., Bonifer, C., Bakkers, J., Abdelilah-Seyfried, S., Hummel, M. and Rosenbauer, F.
Blood 118 (8): 2275-2284. 25 August 2011

Apical membrane maturation and cellular rosette formation during morphogenesis of the zebrafish lateral line.
Hava, D., Forster, U., Matsuda, M., Cui, S., Link, B.A., Eichhorst, J., Wiesner, B., Chitnis, A. and Abdelilah-Seyfried, S.
Journal of Cell Science 122 (Pt 5): 687-695. 1 March 2009

Neuron navigator 3a regulates liver organogenesis during zebrafish embryogenesis.
Klein, C., Mikutta, J., Krueger, J., Scholz, K., Brinkmann, J., Liu, D., Veerkamp, J., Siegel, D., Abdelilah-Seyfried, S. and le Noble, F.
Development 138 (10): 1935-1945. 15 May 2011

Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development.
Kur, E., Christa, A., Veth, K.N., Gajera, C.R., Andrade-Navarro, M.A., Zhang, J., Willer, J.R., Gregg, R.G., Abdelilah-Seyfried, S., Bachmann, S., Link, B.A., Hammes, A. and Willnow, T.E.
Developmental Dynamics 240 (6): 1567-1577. June 2011

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Lange, M., Kaynak, B., Foerster, U.B., Toenjes, M., Fischer, J.J., Grimm, C., Schlesinger, J., Just, S., Dunkel, I., Krueger, T., Mebus, S., Lehrach, H., Lurz, R., Gobom, J., Rottbauer, W., Abdelilah-Seyfried, S. and Sperling, S.
Genes & Development 22 (17): 2370-2384. 1 September 2008

Large-scale zebrafish embryonic heart dissection for transcriptional analysis.
Lombardo, V.A., Otten, C. and Abdelilah-Seyfried, S.
Journal of Visualized Experiments (95) 12 January 2015

Cell tracking using photoconvertible proteins during zebrafish development.
Lombardo, V.A., Sporbert, A. and Abdelilah-Seyfried, S.
Journal of Visualized Experiments (67): e4350. 28 September 2012

Mutations affecting development of the zebrafish retina.
Malicki, J., Neuhauss, S.C., Schier, A.F., Solnica-Krezel, L., Stemple, D.L., Stainier, D.Y., Abdelilah, S., Zwartkruis, F., Rangini, Z. and Driever, W.
Development 123 : 263-273. December 1996

Mutations affecting development of the zebrafish ear.
Malicki, J., Schier, A.F., Solnica-Krezel, L., Stemple, D.L., Neuhauss, S.C., Stainier, D.Y., Abdelilah, S., Rangini, Z., Zwartkruis, F. and Driever, W.
Development 123 : 275-283. December 1996

Regulation of neurocoel morphogenesis by Pard6 gamma b.
Munson, C., Huisken, J., Bit-Avragim, N., Kuo, T., Dong, P.D., Ober, E.A., Verkade, H., Abdelilah-Seyfried, S. and Stainier, D.Y.
Developmental Biology 324 (1): 41-54. 1 December 2008

Mutations affecting craniofacial development in zebrafish.
Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Abdelilah, S., Stainier, D.Y. and Driever, W.
Development 123 : 357-367. December 1996

A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation.
Nyholm, M.K., Abdelilah-Seyfried, S. and Grinblat, Y.
Journal of Cell Science 122 (Pt 12): 2137-2148. 15 June 2009

Laser-inflicted injury of zebrafish embryonic skeletal muscle.
Otten, C. and Abdelilah-Seyfried, S.
Journal of Visualized Experiments 30 (71): e4351. 30 January 2013

Xirp proteins mark injured skeletal muscle in zebrafish.
Otten, C., van der Ven, P.F., Lewrenz, I., Paul, S., Steinhagen, A., Busch-Nentwich, E., Eichhorst, J., Wiesner, B., Stemple, D., Straehle, U., Fuerst, D.O. and Abdelilah-Seyfried, S.
PLoS ONE 7 (2): e31041. 15 February 2012

Regulation of β1 integrin-Klf2-mediated angiogenesis by CCM proteins.
Renz, M., Otten, C., Faurobert, E., Rudolph, F., Zhu, Y., Boulday, G., Duchene, J., Mickoleit, M., Dietrich, A.C., Ramspacher, C., Steed, E., Manet-Dupe, S., Benz, A., Hassel, D., Vermot, J., Huisken, J., Tournier-Lasserve, E., Felbor, U., Sure, U., Albiges-Rizo, C. and Abdelilah-Seyfried, S.
Developmental Cell 32 (2): 181-190. 26 January 2015

Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis.
Rohr, S., Bit-Avragim, N. and Abdelilah-Seyfried, S.
Development 133 (1): 107-115. January 2006

Asymmetric involution of the myocardial field drives heart tube formation in zebrafish.
Rohr, S., Otten, C. and Abdelilah-Seyfried, S.
Circulation Research 102 (2): e12-e19. 1 February 2008

Mutations affecting the development of the embryonic zebrafish brain.
Schier, A.F., Neuhauss, S.C., Harvey, M., Malicki, J., Solnica-Krezel, L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Stemple, D.L., Rangini, Z., Yang, H. and Driever, W.
Development 123 : 165-178. December 1996

Non-SMC condensin I complex proteins control chromosome segregation and survival of proliferating cells in the zebrafish neural retina.
Seipold, S., Priller, F.C., Goldsmith, P., Harris, W.A., Baier, H. and Abdelilah-Seyfried, S.
BMC Developmental Biology 9 (1): 40. 8 July 2009

Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish.
Solnica-Krezel, L., Stemple, D.L., Mountcastle-Shah, E., Rangini, Z., Neuhauss, S.C., Malicki, J., Schier, A.F., Stainier, D.Y., Zwartkruis, F., Abdelilah, S. and Driever, W.
Development 123 : 67-80. December 1996

Mutations affecting development of the notochord in zebrafish.
Stemple, D.L., Solnica-Krezel, L., Zwartkruis, F., Neuhauss, S.C., Schier, A.F., Malicki, J., Stainier, D.Y., Abdelilah, S., Rangini, Z., Mountcastle-Shah, E. and Driever, W.
Development 123 : 117-128. December 1996

Lethal giant larvae 2 regulates development of the ciliated organ Kupffer's vesicle.
Tay, H.G., Schulze, S.K., Compagnon, J., Foley, F.C., Heisenberg, C.P., Yost, H.J., Abdelilah-Seyfried, S. and Amack, J.D.
Development 140 (7): 1550-1559. April 2013

Unilateral dampening of Bmp activity by Nodal generates cardiac left-right asymmetry.
Veerkamp, J., Rudolph, F., Cseresnyes, Z., Priller, F., Otten, C., Renz, M., Schaefer, L. and Abdelilah-Seyfried, S.
Developmental Cell 24 (6): 660-667. 25 March 2013

Hematopoietic mutations in the zebrafish.
Weinstein, B.M., Schier, A.F., Abdelilah, S., Malicki, J., Solnica-Krezel, L., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Driever, W. and Fishman, M.C.
Development 123 : 303-309. December 1996

PI4K2β/AP-1-based TGN-endosomal sorting regulates Wnt signaling.
Wieffer, M., Cibrian Uhalte, E., Posor, Y., Otten, C., Branz, K., Schuetz, I., Moessinger, J., Schu, P., Abdelilah-Seyfried, S., Krauss, M. and Haucke, V.
Current Biology 23 (21): 2185-2190. 4 November 2013

The Drosophila LIM-only gene, dLMO, is mutated in Beadex alleles and might represent an evolutionarily conserved function in appendage development.
Zeng, C., Justice, N.J., Abdelilah, S., Chan, Y.M., Jan, L.Y. and Jan, Y.N.
Proceedings of the National Academy of Sciences of the United States of America 95 (18): 10637-10642. 1 September 1998

Involvement of claudins in zebrafish brain ventricle morphogenesis.
Zhang, J., Liss, M., Wolburg, H., Blasig, I.E. and Abdelilah-Seyfried, S.
Annals of the New York Academy of Sciences 1257 (1): 193-198. June 2012

Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion.
Zhang, J., Piontek, J., Wolburg, H., Piehl, C., Liss, M., Otten, C., Christ, A., Willnow, T.E., Blasig, I.E. and Abdelilah-Seyfried, S.
Proceedings of the National Academy of Sciences of the United States of America 107 (4): 1425-1430. 26 January 2010

Bmp signaling exerts opposite effects on cardiac differentiation.
de Pater, E., Ciampricotti, M., Priller, F., Veerkamp, J., Strate, I., Smith, K., Lagendijk, A.K., Schilling, T.F., Herzog, W., Abdelilah-Seyfried, S., Hammerschmidt, M. and Bakkers, J.
Circulation Research 110 (4): 578-587. 17 February 2012

Akalin, Altuna (BIMSB)

Transcriptional features of genomic regulatory blocks.
Akalin, A., Fredman, D., Arner, E, Dong, X, Bryne, JC, Suzuki, H., Daub, CO, Hayashizaki, Y and Lenhard, B
Genome Biology 10 (4): R38. 19 April 2009

Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia.
Akalin, A., Garrett-Bakelman, F.E., Kormaksson, M., Busuttil, J., Zhang, L., Khrebtukova, I., Milne, T.A., Huang, Y., Biswas, D., Hess, J.L., Allis, C.D., Roeder, R.G., Valk, P.J.M., Loewenberg, B., Delwel, R., Fernandez, H.F., Paietta, E., Tallman, M.S., Schroth, G.P., Mason, C.E., Melnick, A. and Figueroa, M.E.
PLoS Genetics 8 (6): e1002781. 21 June 2012

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles.
Akalin, A., Kormaksson, M., Li, S., Garrett-Bakelman, F.E., Figueroa, M.E., Melnick, A. and Mason, C.E.
Genome Biology 13 (10): R87. 3 October 2012

Computational genomics with R.
Akalin, A.
Chapman and Hall/CRC Computational Biology Series . CRC Press LLC, Milton. ISBN 9781498781855 2020

genomation: a toolkit to summarize, annotate and visualize genomic intervals.
Akalin, A., Franke, V., Vlahoviček, K., Mason, C.E. and Schübeler, D.
Bioinformatics 31 (7): 1127-1129. 1 April 2015

Zebrafish enhancer detection (ZED) vector: a new tool to facilitate transgenesis and the functional analysis of cis-regulatory regions in zebrafish.
Bessa, J., Tena, J.J., de la Calle-Mustienes, E., Fernandez-Minan, A., Naranjo, S., Fernandez, A., Montoliu, L., Akalin, A., Lenhard, B., Casares, F. and Gomez-Skarmeta, J.L.
Developmental Dynamics 238 (9): 2409-2417. September 2009

DoRiNA 2.0-upgrading the doRiNA database of RNA interactions in post-transcriptional regulation.
Blin, K., Dieterich, C., Wurmus, R., Rajewsky, N., Landthaler, M. and Akalin, A.
Nucleic Acids Research 43 (Database issue): D160-D167. 28 January 2015

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C., Rom, A., Franke, V., Imami, K., Arrey, G., Terne, M., Woehler, A., Akalin, A., Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V., Berruezo-Llacuna, M., Altwasser, R., Winkler, W., Sundaravinayagam, D., Balasubramanian, S., Caganova, M., Graf, R., Rahjouei, A., Henke, M.T., Driesner, M., Keller, L., Prigione, A., Janz, M., Akalin, A. and Di Virgilio, M.
Journal of Experimental Medicine 217 (10): e20200137. 5 October 2020

Nuclear organization in the spinal cord depends on motor neuron lamination orchestrated by catenin and afadin function.
Dewitz, C., Pimpinella, S., Hackel, P., Akalin, A., Jessell, T.M. and Zampieri, N.
Cell Reports 22 (7): 1681-1694. 13 February 2018

Translog, a web browser for studying the expression divergence of homologous genes.
Dong, X., Akalin, A., Sharma, Y. and Lenhard, B.
BMC Bioinformatics 11 (Suppl 1): S59. 18 January 2010

Complex loci in human and mouse genomes.
Engstroem, P.G., Suzuki, H., Ninomiya, N., Akalin, A., Sessa, L., Lavorgna, G., Brozzi, A., Luzi, L., Tan, S.L., Yang, L., Kunarso, G., Ng, E.L.C., Batalov, S., Wahlestedt, C., Kai, C., Kawai, J., Carninci, P., Hayashizaki, Y., Wells, C., Bajic, V.B., Orlando, V., Reid, J.F., Lenhard, B. and Lipovich, L.
PLoS Genetics 2 (4): 564-577. 28 April 2006

RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.
Ferrai, C., Torlai Triglia, E., Risner-Janiczek, J.R., Rito, T., Rackham, O.J.L., De Santiago, I., Kukalev, A., Nicodemi, M., Akalin, A., Li, M., Ungless, M.A. and Pombo, A.
Molecular Systems Biology 13 (10): 946. 16 October 2017

Parallel genetics of regulatory sequences using scalable genome editing in vivo.
Froehlich, J.J., Uyar, B., Herzog, M., Theil, K., Glažar, P., Akalin, A. and Rajewsky, N.
Cell Reports 35 (2): 108988. 13 April 2021

The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy.
Grüning, B.A., Fallmann, J., Yusuf, D., Will, S., Erxleben, A., Eggenhofer, F., Houwaart, T., Batut, B., Videm, P., Bagnacani, A., Wolfien, M., Lott, S.C., Hoogstrate, Y., Hess, W.R., Wolkenhauer, O., Hoffmann, S., Akalin, A., Ohler, U., Stadler, P.F. and Backofen, R.
Nucleic Acids Research 45 (W1): W560-W566. 3 July 2017

Two independent transcription initiation codes overlap on vertebrate core promoters.
Haberle, V., Li, N., Hadzhiev, Y., Plessy, C., Previti, C., Nepal, C., Gehrig, J., Dong, X., Akalin, A., Suzuki, A.M., van IJcken, W.F.J., Armant, O., Ferg, M., Strähle, U., Carninci, P., Müller, F. and Lenhard, B.
Nature 507 (7492): 381-385. 20 March 2014

Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates.
Kikuta, H., Laplante, M., Navratilova, P., Komisarczuk, A.Z., Engstroem, P.G., Fredman, D., Akalin, A., Caccamo, M., Sealy, I., Howe, K., Ghislain, J., Pezeron, G., Mourrain, P., Ellingsen, S., Oates, A.C., Thisse, C., Thisse, B., Foucher, I., Adolf, B., Geling, A., Lenhard, B. and Becker, T.S.
Genome Research 17 (5): 545-555. May 2007

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M., Franke, V., Brandt, B., Lowenstein, E.D., Schöwel, V., Spuler, S., Akalin, A. and Birchmeier, C.
Nature Communications 11 : 6375. 11 December 2020

Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M., Mikuda, N., Höpken, U.E., Kärgel, E., Uyar, B., Tufan, A.B., Milanovic, M., Sun, W., Krahn, I., Schleich, K., von Hoff, L., Hinz, M., Willenbrock, M., Jungmann, S., Akalin, A., Lee, S., Schmidt-Ullrich, R., Schmitt, C.A. and Scheidereit, C.
EMBO Journal 40 (6): e104296. 15 March 2021

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E., Ofenbauer, A., Bulut, S.I., Uyar, B., Baytek, G., Sommermeier, A., Seelk, S., He, M., Hirsekorn, A., Vucicevic, D., Akalin, A., Diecke, S., Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

Deep learning for genomics using Janggu.
Kopp, W., Monti, R., Tamburrini, A., Ohler, U. and Akalin, A.
Nature Communications 11 (1): 3488. 13 July 2020

Social networks and protest participation: evidence from 130 million Twitter users.
Larson, J.M., Nagler, J., Ronen, J. and Tucker, J.A.
American Journal of Political Science 63 (3): 690-705. July 2019

Spatio-temporal, optogenetic control of gene expression in organoids.
Legnini, I., Emmenegger, L., Zappulo, A., Wurmus, R., Oliveras Martinez, A., Cerda Jara, C., Boltengagen, A., Hessler, T., Mastrobuoni, G., Rybak-Wolf, A., Kempa, S., Zinzen, R.P., Woehler, A. and Rajewsky, N.
bioRxiv : 2021.09.26.461850v3. 9 February 2022

Predicting lethal courses in critically ill COVID-19 patients using a machine learning model trained on patients with non-COVID-19 viral pneumonia.
Lichtner, G., Balzer, F., Haufe, S., Giesa, N., Schiefenhövel, F., Schmieding, M., Jurth, C., Kopp, W., Akalin, A., Schaller, S.J., Weber-Carstens, S., Spies, C. and von Dincklage, F.
Scientific Reports 11 (1): 13205. 24 June 2021

Induction of sarcomas by mutant IDH2.
Lu, C., Venneti, S., Akalin, A., Fang, F., Ward, P.S., Dematteo, R.G., Intlekofer, A.M., Chen, C., Ye, J., Hameed, M., Nafa, K., Agaram, N.P., Cross, J.R., Khanin, R., Mason, C.E., Healey, J.H., Lowe, S.W., Schwartz, G.K., Melnick, A. and Thompson, C.B.
Genes & Development 27 (18): 1986-1998. 15 September 2013

Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
McGarvey, A.C., Kopp, W., Vučićević, D., Mattonet, K., Kempfer, R., Hirsekorn, A., Bilić, I., Gil, M., Trinks, A., Merks, A.M., Panáková, D., Pombo, A., Akalin, A., Junker, J.P., Stainier, D.Y.R., Garfield, D., Ohler, U. and Lacadie, S.A.
Cell Genomics 2 (1): 100083. 13 January 2022

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K., Kirchner, M., Uyar, B., Cheng, J.Y., Russo, G., Hernandez-Miranda, L.R., Szymborska, A., Zauber, H., Rudolph, I.M., Willnow, T.E., Akalin, A., Haucke, V., Gerhardt, H., Birchmeier, C., Kühn, R., Krauss, M., Diecke, S., Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N., Kolesnichenko, M., Beaudette, P., Popp, O., Uyar, B., Sun, W., Tufan, A.B., Perder, B., Akalin, A., Chen, W., Mertins, P., Dittmar, G., Hinz, M. and Scheidereit, C.
EMBO Journal 37 (24): e98658. 14 December 2018

Deciphering human ribonucleoprotein regulatory networks.
Mukherjee, N., Wessels, H.H., Lebedeva, S., Sajek, M., Ghanbari, M., Garzia, A., Munteanu, A., Yusuf, D., Farazi, T., Hoell, J.I., Akat, K.M., Akalin, A., Tuschl, T. and Ohler, U.
Nucleic Acids Research 47 (2): 570-581. 25 January 2019

Differential evolution of the 13 Atlantic salmon Hox clusters.
Mungpakdee, S., Seo, H.C., Angotzi, A.R., Dong, X., Akalin, A. and Chourrout, D.
Molecular Biology and Evolution 25 (7): 1333-1343. July 2008

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors.
Möller, J., Isbilir, A., Sungkaworn, T., Osberg, B., Karathanasis, C., Sunkara, V., Grushevskyi, E.O., Bock, A., Annibale, P., Heilemann, M., Schütte, C. and Lohse, M.J.
Nature Chemical Biology 16 (9): 946-954. September 2020

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S., Uyar, B., He, M., Krause, A., Vitrinel, B., Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S., Akalin, A. and Tursun, B.
Aging Cell 18 (6): e13012. December 2019

Dynamic regulation of the transcription initiation landscape at single nucleotide resolution during vertebrate embryogenesis.
Nepal, C., Hadzhiev, Y., Previti, C., Haberle, V., Li, N., Takahashi, H., Suzuki, A.M.M., Sheng, Y., Abdelhamid, R.F., Anand, S., Gehrig, J., Akalin, A., Kockx, C.E.M., van der Sloot, A.A.J., van Ijcken, W.F.J., Armant, O., Rastegar, S., Watson, C., Strähle, U., Stupka, E., Carninci, P., Lenhard, B. and Müller, F.
Genome Research 23 (11): 1938-1950. November 2013

NanoCAGE analysis of the mouse olfactory epithelium identifies the expression of vomeronasal receptors and of proximal LINE elements.
Pascarella, G., Lazarevic, D., Plessy, C., Bertin, N., Akalin, A., Vlachouli, C., Simone, R., Faulkner, G.J., Zucchelli, S., Kawai, J., Daub, C.O., Hayashizaki, Y., Lenhard, B., Carninci, P. and Gustincich, S.
Frontiers in Cellular Neuroscience 8 : 41. 18 February 2014

Promoter architecture of mouse olfactory receptor genes.
Plessy, C., Pascarella, G., Bertin, N., Akalin, A., Carrieri, C., Vassalli, A., Lazarevic, D., Severin, J., Vlachouli, C., Simone, R., Faulkner, G.J., Kawai, J., Daub, C.O., Zucchelli, S., Hayashizaki, Y., Mombaerts, P., Lenhard, B., Gustincich, S. and Carninci, P.
Genome Research 22 (3): 486-497. March 2012

Cis-regulatory characterization of sequence conservation surrounding the Hox4 genes.
Punnamoottil, B., Herrmann, C., Pascual-Anaya, J., D'Aniello, S., Garcia-Fernandez, J., Akalin, A., Becker, T.S. and Rinkwitz, S.
Developmental Biology 340 (2): 269-282. 15 April 2010

Functional annotation of human long noncoding RNAs via molecular phenotyping.
Ramilowski, J.A., Yip, C.W., Agrawal, S., Chang, J.C., Ciani, Y., Kulakovskiy, I.V., Mendez, M., Ooi, J.L.C., Ouyang, J.F., Parkinson, N., Petri, A., Roos, L., Severin, J., Yasuzawa, K., Abugessaisa, I., Akalin, A., Antonov, I.V., Arner, E., Bonetti, A., Bono, H., Borsari, B., Brombacher, F., Cameron, C.J.F., Cannistraci, C.V., Cardenas, R., Cardon, M., Chang, H., Dostie, J., Ducoli, L., Favorov, A., Fort, A., Garrido, D., Gil, N., Gimenez, J., Guler, R., Handoko, L., Harshbarger, J., Hasegawa, A., Hasegawa, Y., Hashimoto, K., Hayatsu, N., Heutink, P., Hirose, T., Imada, E.L., Itoh, M., Kaczkowski, B., Kanhere, A., Kawabata, E., Kawaji, H., Kawashima, T., Kelly, S.T., Kojima, M., Kondo, N., Koseki, H., Kouno, T., Kratz, A., Kurowska-Stolarska, M., Kwon, A.T.J., Leek, J., Lennartsson, A., Lizio, M., López-Redondo, F., Luginbühl, J., Maeda, S., Makeev, V.J., Marchionni, L., Medvedeva, Y.A., Minoda, A., Müller, F., Muñoz-Aguirre, M., Murata, M., Nishiyori, H., Nitta, K.R., Noguchi, S., Noro, Y., Nurtdinov, R., Okazaki, Y., Orlando, V., Paquette, D., Parr, C.J.C., Rackham, O.J.L., Rizzu, P., Sánchez Martinez, D.F., Sandelin, A., Sanjana, P., Semple, C.A.M., Shibayama, Y., Sivaraman, D.M., Suzuki, T., Szumowski, S.C., Tagami, M., Taylor, M.S., Terao, C., Thodberg, M., Thongjuea, S., Tripathi, V., Ulitsky, I., Verardo, R., Vorontsov, I.E., Yamamoto, C., Young, R.S., Baillie, J.K., Forrest, A.R.R., Guigó, R., Hoffman, M.M., Hon, C.C., Kasukawa, T., Kauppinen, S., Kere, J., Lenhard, B., Schneider, C., Suzuki, H., Yagi, K., de Hoon, M.J.L., Shin, J.W. and Carninci, P.
Genome Research 30 (7): 1060-1072. July 2020

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Rampal, R., Akalin, A., Madzo, J., Vasanthakumar, A., Pronier, E., Patel, J., Li, Y., Ahn, J., Abdel-Wahab, O., Shih, A., Lu, C., Ward, P.S., Tsai, J.J., Hricik, T., Tosello, V., Tallman, J.E., Zhao, X., Daniels, D., Dai, Q., Ciminio, L., Aifantis, I., He, C., Fuks, F., Tallman, M.S., Ferrando, A., Nimer, S., Paietta, E., Thompson, C.B., Licht, J.D., Mason, C.E., Godley, L.A., Melnick, A., Figueroa, M.E. and Levine, R.L.
Cell Reports 9 (5): 1841-1855. 11 December 2014

An atlas of combinatorial transcriptional regulation in mouse and man.
Ravasi, T., Suzuki, H., Cannistraci, C.V., Katayama, S., Bajic, V.B., Tan, K., Akalin, A., Schmeier, S., Kanamori-Katayama, M., Bertin, N., Carninci, P., Daub, C.O., Forrest, A.R.R., Gough, J., Grimmond, S., Han, J.H., Hashimoto, T., Hide, W., Hofmann, O., Kamburov, A., Kaur, M., Kawaji, H., Kubosaki, A., Lassmann, T., van Nimwegen, E., MacPherson, C.R., Ogawa, C., Radovanovic, A., Schwartz, A., Teasdale, R.D., Tegner, J., Lenhard, B., Teichmann, S.A., Arakawa, T., Ninomiya, N., Murakami, K., Tagami, M., Fukuda, S., Imamura, K., Kai, C., Ishihara, R., Kitazume, Y., Kawai, J., Hume, D.A., Ideker, T. and Hayashizaki, Y.
Cell 140 (5): 744-752. 5 March 2010

Evaluation of colorectal cancer subtypes and cell lines using deep learning.
Ronen, J., Hayat, S. and Akalin, A.
Life Science Alliance 2 (6): 201900517. December 2019

Dissecting the transcriptional regulatory properties of human chromosome 16 highly conserved non-coding regions.
Royo, J.L., Hidalgo, C., Roncero, Y., Seda, M.A., Akalin, A., Lenhard, B., Casares, F. and Gomez-Skarmeta, J.L.
PLoS ONE 6 (9): e24824. 13 September 2011

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T., Meyer, K., Roske, Y., Uyar, B., Akalin, A., Imami, K., Ishihama, Y., Daumke, O. and Selbach, M.
Nature Communications 15 (1): 3146. 11 April 2024

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
Schroder, K., Irvine, K.M., Taylor, M.S., Bokil, N.J., Le Cao, K.A., Masterman, K.A., Labzin, L.I., Semple, C.A., Kapetanovic, R., Fairbairn, L., Akalin, A., Faulkner, G.J., Baillie, J.K., Gongora, M., Daub, C.O., Kawaji, H., McLachlan, G.J., Goldman, N., Grimmond, S.M., Carninci, P., Suzuki, H., Hayashizaki, Y., Lenhard, B., Hume, D.A. and Sweet, M.J.
Proceedings of the National Academy of Sciences of the United States of America 109 (16): E944-E953. 17 April 2012

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F., de Castro Cuadrat, R.R., Wyler, E., Wurmus, R., Deter, A., Quedenau, C., Dohmen, J., Faxel, M., Borodina, T., Blume, A., Freimuth, J., Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B., Franke, V., Barke, N., Altmüller, J., Rajewsky, N., Landthaler, M. and Akalin, A.
Science of the Total Environment 853 : 158931. 20 December 2022

Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge.
Sieberts, S.K., Schaff, J., Duda, M., Pataki, B.Á., Sun, M., Snyder, P., Daneault, J.F., Parisi, F., Costante, G., Rubin, U., Banda, P., Chae, Y., Chaibub Neto, E., Dorsey, E.R., Aydın, Z., Chen, A., Elo, L.L., Espino, C., Glaab, E., Goan, E., Golabchi, F.N., Görmez, Y., Jaakkola, M.K., Jonnagaddala, J., Klén, R., Li, D., McDaniel, C., Perrin, D., Perumal, T.M., Rad, N.M., Rainaldi, E., Sapienza, S., Schwab, P., Shokhirev, N., Venäläinen, M.S., Vergara-Diaz, G., Zhang, Y., Wang, Y., Guan, Y., Brunner, D., Bonato, P., Mangravite, L.M. and Omberg, L.
NPJ Digital Medicine 4 (1): 53. 19 March 2021

Scalable workflows and reproducible data analysis for genomics.
Strozzi, F., Janssen, R., Wurmus, R., Crusoe, M.R., Githinji, G., Di Tommaso, P., Belhachemi, D., Möller, S., Smant, G., de Ligt, J. and Prins, P.
Methods in Molecular Biology 1910 : 723-745. 2019

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.
Suzuki, H, Forrest, ARR, van Nimwegen, E, Daub, CO, Balwierz, PJ, Irvine, KM, Lassmann, T, Ravasi, T, Hasegawa, Y, de Hoon, MJL, Katayama, S, Schroder, K, Carninci, P, Tomaru, Y, Kanamori-Katayama, M, Kubosaki, A, Akalin, A., Ando, Y, Arner, E, Asada, M, Asahara, H, Bailey, T, Bajic, VB, Bauer, D, Beckhouse, AG, Bertin, N, Björkegren, J, Brombacher, F, Bulger, E, Chalk, AM, Chiba, J, Cloonan, N, Dawe, A, Dostie, J, Engstroem, PG, Essack, M, Faulkner, GJ, Fink, JL, Fredman, D, Fujimori, K, Furuno, M, Gojobori, T, Gough, J, Grimmond, SM, Gustafsson, M, Hashimoto, M, Hashimoto, T, Hatakeyama, M, Heinzel, S, Hide, W, Hofmann, O, Hörnquist, M, Huminiecki, L, Ikeo, K, Imamoto, N, Inoue, S, Inoue, Y, Ishihara, R, Iwayanagi, T, Jacobsen, A, Kaur, M, Kawaji, H, Kerr, MC, Kimura, R, Kimura, S, Kimura, Y, Kitano, H, Koga, H, Kojima, T, Kondo, S, Konno, T, Krogh, A, Kruger, A, Kumar, A, Lenhard, B, Lennartsson, A, Lindow, M, Lizio, M, Macpherson, C, Maeda, N, Maher, CA, Maqungo, M, Mar, J, Matigian, NA, Matsuda, H, Mattick, JS, Meier, S, Miyamoto, S, Miyamoto-Sato, E, Nakabayashi, K, Nakachi, Y, Nakano, M, Nygaard, S, Okayama, T, Okazaki, Y, Okuda-Yabukami, H, Orlando, V, Otomo, J, Pachkov, M, Petrovsky, N, Plessy, C, Quackenbush, J, Radovanovic, A, Rehli, M, Saito, R, Sandelin, A, Schmeier, S, Schönbach, C, Schwartz, AS, Semple, CA, Sera, M, Severin, J, Shirahige, K, Simons, C, St Laurent, G, Suzuki, M, Suzuki, T, Sweet, MJ, Taft, RJ, Takeda, S, Takenaka, Y, Tan, K, Taylor, MS, Teasdale, RD, Tegnér, J, Teichmann, S, Valen, E, Wahlestedt, C, Waki, K, Waterhouse, A, Wells, CA, Winther, O, Wu, L, Yamaguchi, K, Yanagawa, H, Yasuda, J, Zavolan, M, Hume, DA, Arakawa, T, Fukuda, S, Imamura, K, Kai, C, Kaiho, A, Kawashima, T, Kawazu, C, Kitazume, Y, Kojima, M, Miura, H, Murakami, K, Murata, M, Ninomiya, N, Nishiyori, H, Noma, S, Ogawa, C, Sano, T, Simon, C, Tagami, M, Takahashi, Y, Kawai, J and Hayashizaki, Y
Nature Genetics 41 (5): 553-562. May 2009

A single dose of cocaine rewires the 3D genome structure of midbrain dopamine neurons.
Szabó, D., Franke, V., Bianco, S., Batiuk, M.Y., Paul, E.J., Kukalev, A., Pfisterer, U.G., Irastorza-Azcarate, I., Chiariello, A.M., Demharter, S., Zea-Redondo, L., Lopez-Atalaya, J.P., Nicodemi, M., Akalin, A., Khodosevich, K., Ungless, M.A., Winick-Ng, W. and Pombo, A.
bioRxiv : 2024.05.10.593308. 12 May 2024

Single-cell analyses of aging, inflammation and senescence.
Uyar, B., Palmer, D., Kowald, A., Escobar, H.M., Barrantes, I., Möller, S., Akalin, A. and Fuellen, G.
Ageing Research Reviews 64 : 101156. December 2020

RCAS: an RNA centric annotation system for transcriptome-wide regions of interest.
Uyar, B., Yusuf, D., Wurmus, R., Rajewsky, N., Ohler, U. and Akalin, A.
Nucleic Acids Research 45 (10): e91. 2 June 2017

The association between salt taste perception, mediterranean diet and metabolic syndrome: a cross-sectional study.
Veček, N.N., Mucalo, L., Dragun, R., Miličević, T., Pribisalić, A., Patarčić, I., Hayward, C., Polašek, O. and Kolčić, I.
Nutrients 12 (4): 1164. April 2020

Herpesviral induction of germline transcription factor DUX4 is critical for viral gene expression.
Walter, S., Franke, V., Drayman, N., Wyler, E., Tay, S., Landthaler, M., Akalin, A., Ensser, A. and Full, F.
bioRxiv : 2021.03.24.436599. 24 March 2021

Cell-type specialization is encoded by specific chromatin topologies.
Winick-Ng, W., Kukalev, A., Harabula, I., Zea-Redondo, L., Szabó, D., Meijer, M., Serebreni, L., Zhang, Y., Bianco, S., Chiariello, A.M., Irastorza-Azcarate, I., Thieme, C.J., Sparks, T.M., Carvalho, S., Fiorillo, L., Musella, F., Irani, E., Triglia, E.T., Kolodziejczyk, A.A., Abentung, A., Apostolova, G., Paul, E.J., Franke, V., Kempfer, R., Akalin, A., Teichmann, S.A., Dechant, G., Ungless, M.A., Nicodemi, M., Welch, L., Castelo-Branco, G. and Pombo, A.
Nature 599 (7886): 684-691. 25 November 2021

HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K., Franke, V., Uyar, B., Wurmus, R., Bulut, S., Tursun, B. and Akalin, A.
Nucleic Acids Research : gkz460. 20 June 2019

Strategies for analyzing bisulfite sequencing data.
Wreczycka, K., Gosdschan, A., Yusuf, D., Grüning, B., Assenov, Y. and Akalin, A.
Journal of Biotechnology 261 : 105-115. 10 November 2017

PiGx: reproducible genomics analysis pipelines with GNU Guix.
Wurmus, R., Uyar, B., Osberg, B., Franke, V., Gosdschan, A., Wreczycka, K., Ronen, J. and Akalin, A.
GigaScience 7 (12): giy123. 1 December 2018

Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program.
Wyler, E., Franke, V., Menegatti, J., Kocks, C., Boltengagen, A., Praktiknjo, S., Walch-Rückheim, B., Bosse, J., Rajewsky, N., Grässer, F., Akalin, A. and Landthaler, M.
Nature Communications 10 (1): 4878. 25 October 2019

Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.
Wyler, E., Menegatti, J., Franke, V., Kocks, C., Boltengagen, A., Hennig, T., Theil, K., Rutkowski, A., Ferrai, C., Baer, L., Kermas, L., Friedel, C., Rajewsky, N., Akalin, A., Dölken, L., Grässer, F. and Landthaler, M.
Genome Biology 18 (1): 209. 31 October 2017

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E., Mösbauer, K., Franke, V., Diag, A., Gottula, L.T., Arsiè, R., Klironomos, F., Koppstein, D., Hönzke, K., Ayoub, S., Buccitelli, C., Hoffmann, K., Richter, A., Legnini, I., Ivanov, A., Mari, T., Del Giudice, S., Papies, J., Praktiknjo, S., Meyer, T.F., Müller, M.A., Niemeyer, D., Hocke, A., Selbach, M., Akalin, A., Rajewsky, N., Drosten, C. and Landthaler, M.
iScience 24 (3): 102151. 19 March 2021

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A., van den Bruck, D., Ciolli Mattioli, C., Franke, V., Imami, K., McShane, E., Moreno-Estelles, M., Calviello, L., Filipchyk, A., Peguero-Sanchez, E., Müller, T., Woehler, A., Birchmeier, C., Merino, E., Rajewsky, N., Ohler, U., Mazzoni, E.O., Selbach, M., Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V., McShane, E., Schulz-Beiss, K.W., Patone, G., Schleussner, N., Kolesnichenko, M., Hübner, N., Daumke, O., Selbach, M., Akalin, A., Mathas, S. and Scheidereit, C.
Blood 133 (13): 1489-1494. 28 March 2019

Alexander, Christiane

SLP-2 is required for stress-induced mitochondrial hyperfusion.
Tondera, D., Grandemange, S., Jourdain, A., Karbowski, M., Mattenberger, Y., Herzig, S., Da Cruz, S., Clerc, P., Raschke, I., Merkwirth, C., Ehses, S., Krause, F., Chan, D.C., Alexander, C., Bauer, C., Youle, R., Langer, T. and Martinou, J.C.
EMBO Journal 28 (11): 1589-1600. 3 June 2009

Altmüller, Janine (BIMSB/BIH)

Phenotypic and genetic heterogeneity in a genome-wide linkage study of asthma families.
Altmüller, J., Seidel, C., Lee, Y.A., Loesgen, S., Bulle, D., Friedrichs, F., Jellouschek, H., Kelber, J., Keller, A., Schuster, A., Silbermann, M., Wahlen, W., Wolff, P., Rueschendorf, F., Schlenvoigt, G., Nuernberg, P. and Wjst, M.
BMC Pulmonary Medicine 5 : 1. 5 January 2005

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C., Mouktaroudi, M., Krämer, B., Oestreich, M., Antonakos, N., Nuesch-Germano, M., Gkizeli, K., Bonaguro, L., Reusch, N., Baßler, K., Saridaki, M., Knoll, R., Pecht, T., Kapellos, T.S., Doulou, S., Kröger, C., Herbert, M., Holsten, L., Horne, A., Gemünd, I.D., Rovina, N., Agrawal, S., Dahm, K., van Uelft, M., Drews, A., Lenkeit, L., Bruse, N., Gerretsen, J., Gierlich, J., Becker, M., Händler, K., Kraut, M., Theis, H., Mengiste, S., Domenico, E., Schulte-Schrepping, J., Seep, L., Raabe, J., Hoffmeister, C., ToVinh, M., Keitel, V., Rieke, G., Talevi, V., Skowasch, D., Aziz, N.A., Pickkers, P., van de Veerdonk, F.L., Netea, M.G., Schultze, J.L., Kox, M., Breteler, M.M.B., Nattermann, J., Koutsoukou, A., Giamarellos-Bourboulis, E.J. and Ulas, T.
Genome Medicine 13 (1): 7. 13 January 2021

Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3.
Budde, B.S., Mizumoto, S., Kogawa, R., Becker, C., Altmüller, J., Thiele, H., Rueschendorf, F., Toliat, M.R., Kaleschke, G., Haemmerle, J.M., Hoehne, W., Sugahara, K., Nuernberg, P. and Kennerknecht, I.
Human Genetics 134 (7): 691-704. July 2015

Intramyocardial sprouting tip cells specify coronary arterialization.
Cano, E., Schwarzkopf, J., Kanda, M., Lindberg, E.L., Hollfinger, I., Pogontke, C., Braeuning, C., Fischer, C., Hübner, N. and Gerhardt, H.
Circulation Research 135 (6): 671-684. 30 August 2024

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais, F., Margaritte-Jeannin, P., Barnes, K.C., Cookson, W.O.C., Altmüller, J., Ang, W., Barr, R.G., Beaty, T.H., Becker, A.B., Beilby, J., Bisgaard, H., Bjornsdottir, U.S., Bleecker, E., Bonnelykke, K., Boomsma, D.I., Bouzigon, E., Brightling, C.E., Brossard, M., Brusselle, G.G., Burchard, E., Burkart, K.M., Bush, A., Chan-Yeung, M., Chung, K.F., Couto Alves, A., Curtin, J.A., Custovic, A., Daley, D., de Jongste, J.C., Del-Rio-Navarro, B.E., Donohue, K.M., Duijts, L., Eng, C., Eriksson, J.G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M.A., Freidin, M.B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S.A, Gilliland, F., Granell, R., Graves, P.E., Gudbjartsson, D.F., Haahtela, T., Heckbert, S.R., Heederik, D., Heinrich, J., Helioevaara, M., Henderson, J., Himes, B.E., Hirose, H., Hirschhorn, J.N., Hofman, A., Holt, P., Hottenga, J., Hudson, T.J., Hui, J., Imboden, M., Ivanov, V., Jaddoe, V.W.V., James, A., Janson, C., Jarvelin, M.R., Jarvis, D., Jones, G., Jonsdottir, I., Jousilahti, P., Kabesch, M., Kähönen, M., Kantor, D.B., Karunas, A.S., Khusnutdinova, E., Koppelman, G.H., Kozyrskyj, A.L., Kreiner, E., Kubo, M., Kumar, R., Kumar, A., Kuokkanen, M., Lahousse, L., Laitinen, T., Laprise, C., Lathrop, M., Lau, S., Lee, Y.A., Lehtimaeki, T., Letort, S., Levin, A.M., Li, G., Liang, L., Loehr, L.R., London, S.J., Loth, D.W., Manichaikul, A., Marenholz, I., Martinez, F.J., Matheson, M.C., Mathias, R.A., Matsumoto, K., Mbarek, H., McArdle, W.L., Melbye, M., Melen, E., Meyers, D., Michel, S., Mohamdi, H., Musk, A.W., Myers, R.A., Nieuwenhuis, M.A.E., Noguchi, E., O'Connor, G.T., Ogorodova, L.M., Palmer, C.D., Palotie, A., Park, J.E., Pennell, C.E., Pershagen, G., Polonikov, A., Postma, D.S., Probst-Hensch, N., Puzyrev, V.P., Raby, B.A., Raitakari, O.T., Ramasamy, A., Rich, S.S., Robertson, C.F., Romieu, I., Salam, M.T., Salomaa, V., Schluenssen, V., Scott, R., Selivanova, P.A., Sigsgaard, T., Simpson, A., Siroux, V., Smith, L.J., Solodilova, M., Standl, M., Stefansson, K., Strachan, D.P., Stricker, B.H., Takahashi, A., Thompson, P.J., Thorleifsson, G., Thorsteinsdottir, U., Tiesler, C.M.T., Torgerson, D.G., Tsunoda, T., Uitterlinden, A.G., van der Valk, R.J.P., Vaysse, A., Vedantam, S., von Berg, A., von Mutius, E., Vonk, J.M., Waage, J., Wareham, N.J., Weiss, S.T., White, W.B., Wickman, M., Widén, E., Willemsen, G., Williams, L.K., Wouters, I.M., Yang, J.J., Zhao, J.H., Moffatt, M.F., Ober, C. and Nicolae, D.L.
Nature Genetics 50 (1): 42-53. January 2018

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M., Mücke, M.B., Pallien, T., Markó, L., Sholokh, A., Schächterle, C., Aydin, A., Kidd, A., Walter, S., Esmati, Y., McMurray, B.J., Lato, D.F., Sunaga-Franze, D.Y., Dierks, P.H., Flores, B.I.M., Walker-Gray, R., Gong, M., Merticariu, C., Zühlke, K., Russwurm, M., Liu, T., Batolomaeus, T.U.P., Pautz, S., Schelenz, S., Taube, M., Napieczynska, H., Heuser, A., Eichhorst, J., Lehmann, M., Miller, D.C., Diecke, S., Qadri, F., Popova, E., Langanki, R., Movsesian, M.A., Herberg, F.W., Forslund, S.K., Müller, D.N., Borodina, T., Maass, P.G., Bähring, S., Hübner, N., Bader, M. and Klussmann, E.
Circulation 146 (23): 1758-1778. 6 December 2022

Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
Houwaart, Torsten, Belhaj, S., Tawalbeh, E., Nagels, D., Fröhlich, Y., Finzer, P., Ciruela, P., Sabrià, A., Herrero, M., Andrés, C., Antón, A., Benmoumene, A., Asskali, D., Haidar, H., von Dahlen, J., Nicolai, J., Stiller, M., Blum, J., Lange, C., Adelmann, C., Schroer, B., Osmers, U., Grice, C., Kirfel, P.P., Jomaa, H., Strelow, D., Hülse, L., Pigulla, M., Kreuzer, P., Tyshaieva, A., Weber, J., Wienemann, T., Kohns Vasconcelos, M., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Scholz, C.J., Jazmati, N., Göbels, K., Zotz, R., Pfeffer, K., Timm, J., Ehlkes, L., Walker, A. and Dilthey, A.T.
Eurosurveillance 27 (43): 2101089. 27 October 2022

SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells.
Kalnytska, O., Qvist, P., Kunz, S., Conrad, T., Willnow, T.E. and Schmidt, V.
iScience 27 (1): 108725. 19 January 2024

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Krämer, B., Knoll, R., Bonaguro, L., ToVinh, M., Raabe, J., Astaburuaga-García, R., Schulte-Schrepping, J., Kaiser, K.M., Rieke, G.J., Bischoff, J., Monin, M.B., Hoffmeister, C., Schlabe, S., De Domenico, E., Reusch, N., Händler, K., Reynolds, G., Blüthgen, N., Hack, G., Finnemann, C., Nischalke, H.D., Strassburg, C.P., Stephenson, E., Su, Y., Gardner, L., Yuan, D., Chen, D., Goldman, J., Rosenstiel, P., Schmidt, S.V., Latz, E., Hrusovsky, K., Ball, A.J., Johnson, J.M., Koenig, P.A., Schmidt, F.I., Haniffa, M., Heath, J.R., Kümmerer, B.M., Keitel, V., Jensen, B., Stubbemann, P., Kurth, F., Sander, L.E., Sawitzki, B., Aschenbrenner, A.C., Schultze, J.L. and Nattermann, J.
Immunity 54 (11): 2650-2669. 9 November 2021

A genome-wide screen on the genetics of atopy in a multiethnic European population reveals a major atopy locus on chromosome 3q21.3.
Kurz, T., Altmueller, J., Strauch, K., Rueschendorf, F., Heinzmann, A., Moffatt, M.F., Cookson, W.O.C.M., Inacio, F., Nuernberg, P., Stassen, H.H. and Deichmann, K.A.
Allergy 60 : 192-199. 1 January 2005

Nuclei isolation from adult mouse kidney for single-nucleus RNA-sequencing.
Leiz, J., Hinze, C., Boltengagen, A., Braeuning, C., Kocks, C., Rajewsky, N. and Schmidt-Ott, K.M.
Journal of Visualized Experiments (175): e62901. September 2021

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M., Hartl, K., Heuberger, J., Beccaceci, G., Berger, H., Li, H., Liu, L., Müllerke, S., Conrad, T., Heymann, F., Woehler, A., Tacke, F., Rajewsky, N. and Sigal, M.
Nature Communications 14 (1): 3025. 25 May 2023

Platelet-derived factors dysregulate placental sphingosine-1-phosphate receptor 2 in human trophoblasts.
Lyssy, F., Guettler, J., Brugger, B.A., Stern, C., Forstner, D., Nonn, O., Fischer, C., Herse, F., Wernitznig, S., Hirschmugl, B., Wadsack, C. and Gauster, M.
Reproductive BioMedicine Online 47 (2): 103215. August 2023

Candesartan does not activate PPAR(γ) and its target genes in early gestation trophoblasts.
Neuper, L., Kummer, D., Forstner, D., Guettler, J., Ghaffari-Tabrizi-Wizsy, N., Fischer, C., Juch, H., Nonn, O. and Gauster, M.
International Journal of Molecular Sciences 23 (20): 12326. October 2022

A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A., Bakina, O., Badillo Lisakowski, V., Olivares-Chauvet, P., Conrad, T., Gotthardt, M., Kettenmann, H. and Junker, J.P.
Molecular Systems Biology 19 (2): e11147. 10 February 2023

Senescent syncytiotrophoblast secretion during early onset preeclampsia.
Nonn, O., Debnath, O., Valdes, D.S., Sallinger, K., Secener, A.K., Fischer, C., Tiesmeyer, S., Nimo, J., Kuenzer, T., Ulrich, J., Maxian, T., Knöfler, M., Karau, P., Bartolomaeus, H., Kroneis, T., Frolova, A., Neuper, L., Haase, N., Malt, A., Müller-Bötticher, N., Kräker, K., Kedziora, S., Forstner, D., Eils, R., Schmidt-Ullrich, R., Haider, S., Verlohren, S., Stern, C., Sugulle, M., Jones, S., Thilaganathan, B., Kaitu'u-Lino, T.J., Tong, S., Huppertz, B., El-Heliebi, A., Staff, A.C., Coscia, F., Müller, D.N., Dechend, R., Gauster, M., Ishaque, N. and Herse, F.
Hypertension 23 October 2024 (In Press)

Maternal angiotensin increases placental leptin in early gestation via an alternative renin-angiotensin system pathway: suggesting a link to preeclampsia.
Nonn, O., Fischer, C., Geisberger, S., El-Heliebi, A., Kroneis, T., Forstner, D., Desoye, G., Staff, A.C., Sugulle, M., Dechend, R., Pecks, U., Kollmann, M., Stern, C., Cartwright, J.E., Whitley, G.S., Thilaganathan, B., Wadsack, C., Huppertz, B., Herse, F. and Gauster, M.
Hypertension 77 (5): 1723-1736. May 2021

The neuroinflammatory interleukin-12 signaling pathway drives Alzheimer's disease-like pathology by perturbing oligodendrocyte survival and neuronal homeostasis.
Schneeberger, S., Kim, S.J., Eede, P., Boltengagen, A., Braeuning, C., Andreadou, M., Becher, B., Karaiskos, N., Kocks, C., Rajewsky, N. and Heppner, F.L.
bioRxiv : 2021.04.25.441313. 27 April 2021

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F., de Castro Cuadrat, R.R., Wyler, E., Wurmus, R., Deter, A., Quedenau, C., Dohmen, J., Faxel, M., Borodina, T., Blume, A., Freimuth, J., Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B., Franke, V., Barke, N., Altmüller, J., Rajewsky, N., Landthaler, M. and Akalin, A.
Science of the Total Environment 853 : 158931. 20 December 2022

Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A., Walter, S., Markó, L., McMurray, B.J., Sunaga-Franze, D.Y., Xu, M., Zühlke, K., Russwurm, M., Bartolomaeus, T.U.P., Langanki, R., Qadri, F., Heuser, A., Patzak, A., Forslund, S.K., Bähring, S., Borodina, T., Persson, P.B., Maass, P.G., Bader, M. and Klussmann, E.
Kidney International 104 (2): 388-393. August 2023

Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection clusters based on integrated genomic surveillance, outbreak analysis and contact tracing in an urban setting.
Walker, A., Houwaart, T., Finzer, P., Ehlkes, L., Tyshaieva, A., Damagnez, M., Strelow, D., Duplessis, A., Nicolai, J., Wienemann, T., Tamayo, T., Kohns Vasconcelos, M., Hülse, L., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Däumer, M.P., Thielen, A., Kolbe-Busch, S., Göbels, K., Zotz, R., Pfeffer, K., Timm, J. and Dilthey, A.T.
Clinical Infectious Diseases 74 (6): 1039-1046. 15 March 2022

Swarm Learning for decentralized and confidential clinical machine learning.
Warnat-Herresthal, S., Schultze, H., Shastry, K.L., Manamohan, S., Mukherjee, S., Garg, V., Sarveswara, R., Händler, K., Pickkers, P., Aziz, N.A., Ktena, S., Tran, F., Bitzer, M., Ossowski, S., Casadei, N., Herr, C., Petersheim, D., Behrends, U., Kern, F., Fehlmann, T., Schommers, P., Lehmann, C., Augustin, M., Rybniker, J., Altmüller, J., Mishra, N., Bernardes, J.P., Krämer, B., Bonaguro, L., Schulte-Schrepping, J., De Domenico, E., Siever, C., Kraut, M., Desai, M., Monnet, B., Saridaki, M., Siegel, C.M., Drews, A., Nuesch-Germano, M., Theis, H., Heyckendorf, J., Schreiber, S., Kim-Hellmuth, S., Nattermann, J., Skowasch, D., Kurth, I., Keller, A., Bals, R., Nürnberg, P., Rieß, O., Rosenstiel, P., Netea, M.G., Theis, F., Mukherjee, S., Backes, M., Aschenbrenner, A.C., Ulas, T., Breteler, M.M.B., Giamarellos-Bourboulis, E.J., Kox, M., Becker, M., Cheran, S., Woodacre, M.S., Goh, E.L. and Schultze, J.L.
Nature 594 (7862): 265-270. 10 June 2021

Andrade Navarro, Miguel

Automated genome sequence analysis and annotation.
Andrade, M.A., Brown, N.P., Leroy, C., Hoersch, S., de Daruvar, A., Reich, C., Franchini, A., Tamames, J., Valencia, A., Ouzounis, C. and Sander, C.
Bioinformatics 15 (5): 391-412. May 1999

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N., Naumann, H., Ruzittu, S., Mah, N., Pongrac, I.M., Cozzitorto, C., Hommel, A., Andrade-Navarro, M.A., Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8 : 14127. 13 February 2017

The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo.
Christ, A., Terryn, S., Schmidt, V., Christensen, E.I., Huska, M.R., Andrade-Navarro, M.A., Huebner, N., Devuyst, O., Hammes, A. and Willnow, T.E.
Kidney International 78 (5): 473-477. September 2010

Genie: literature-based gene prioritization at multi genomic scale.
Fontaine, J.F., Priller, F., Barbosa-Silva, A. and Andrade-Navarro, M.A.
Nucleic Acids Research 39 (Suppl 2): W455-W461. July 2011

Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D., Luft, F.C., Bader, M., Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90 (5): 495-508. May 2012

Systematic association of genes to phenotypes by genome and literature mining.
Korbel, J.O., Doerks, T., Jensen, L.J., Perez-Iratxeta, C., Kaczanowski, S., Hooper, S.D., Andrade, M.A. and Bork, P.
PLoS Biology 3 (5): e134. 5 April 2005

Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development.
Kur, E., Christa, A., Veth, K.N., Gajera, C.R., Andrade-Navarro, M.A., Zhang, J., Willer, J.R., Gregg, R.G., Abdelilah-Seyfried, S., Bachmann, S., Link, B.A., Hammes, A. and Willnow, T.E.
Developmental Dynamics 240 (6): 1567-1577. June 2011

Molecular insights into reprogramming-initiation events mediated by the OSKM gene regulatory network.
Mah, N., Wang, Y., Liao, M.C., Prigione, A., Jozefczuk, J., Lichtner, B., Wolfrum, K., Haltmeier, M., Floettmann, M., Schaefer, M., Hahn, A., Mrowka, R., Klipp, E., Andrade-Navarro, M.A. and Adjaye, J.
PLoS ONE 6 (8): e24351. 31 August 2011

Gene annotation from scientific literature using mappings between keyword systems.
Perez, A.J., Perez-Iratxeta, C., Bork, P., Thode, G. and Andrade-Navarro, M.A.
Bioinformatics 20 (13): 2084-2091. 1 January 2004

Update of the G2D tool for prioritization of gene candidates to inherited diseases.
Perez-Iratxeta, C., Bork, P. and Andrade-Navarro, M.A.
Nucleic Acids Research 35 (Web Server Issue): W212-W216. July 2007

Update on XplorMed: a web server for exploring scientific literature.
Perez-Iratxeta, C., Perez, A.J., Bork, P. and Andrade-Navarro, M.A.
Nucleic Acids Research 31 (13): 3866-3868. 1 July 2003

G2D: A tool for mining genes associated with disease.
Perez-Iratxeta, C., Wjst, M., Bork, P. and Andrade, M.A.
BMC Genetics 6 : 45. 22 August 2005

Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence.
Rodríguez-Seguel, E., Mah, N., Naumann, H., Pongrac, I.M., Cerdá-Esteban, N., Fontaine, J.F., Wang, Y., Chen, W., Andrade-Navarro, M.A. and Spagnoli, F.M.
Genes & Development 27 (17): 1932-1946. 1 September 2013

CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A., Qadri, F., Leukel, L., Yilmaz, R., Fontaine, J.F., Sihn, G., Bader, M., Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123 (3): 1343-1347. 1 March 2013

Information extraction from full text scientific articles: Where are the keywords?
Shah, P., Perez-Iratxeta, C., Bork, P. and Andrade, M.A.
BMC Bioinformatics 4 (1): 20. 29 May 2003

Development and application of a DNA microarray-based yeast two-hybrid system.
Suter, B., Fontaine, J.F., Yildirimman, R., Raskó, T., Schaefer, M.H., Rasche, A., Porras, P., Vázquez-Álvarez, B.M., Russ, J., Rau, K., Foulle, R., Zenkner, M., Saar, K., Herwig, R., Andrade-Navarro, M.A. and Wanker, E.E.
Nucleic Acids Research 41 (3): 1496-507. 1 February 2013

A directed protein interaction network for investigating intracellular signal transduction.
Vinayagam, A., Stelzl, U., Foulle, R., Plassmann, S., Zenkner, M., Timm, J., Assmus, H.E., Andrade-Navarro, M.A. and Wanker, E.E.
Science Signaling 4 (189): rs8. 6 September 2011

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K., Ullrich, F., Muench, J., Lazarow, K., Lutter, D., Mah, N., Andrade-Navarro, M.A., von Kries, J.P., Stauber, T. and Jentsch, T.J.
Science 344 (6184): 634-638. 9 May 2014

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P., Kaergel, E., Heinig, M., Fontaine, J.F., Patone, G., Muro, E.M., Mathas, S., Hummel, M., Andrade-Navarro, M.A., Hübner, N. and Scheidereit, C.
Genome Medicine 8 (1): 28. 17 March 2016

Bader, Michael

Cardiovascular hormone systems.
Bader, M., ed.
Wiley-Blackwell, 1-433. ISBN 9783527319206 10 September 2008

Functional characterization of the human atrial essential myosin light chain (hALC-1) in a transgenic rat model.
Abdelaziz, A.I., Segaric, J., Bartsch, H., Petzhold, D., Schlegel, W., Kott, M., Seefeldt, I., Klose, J., Bader, M., Haase, H. and Morano, I.
Journal of Molecular Medicine 82 (4): 265-274. 1 January 2004

Multichannel SQUID system with integrated magnetic shielding for magnetocardiography of mice.
Ackermann, R., Wiekhorst, F., Beck, A., Gutkelch, D., Ruede, F., Schnabel, A., Steinhoff, U., Drung, D., Beyer, J., Assmann, C., Trahms, L., Koch, H., Schurig, T., Fischer, R., Bader, M., Ogata, H. and Kado, H.
IEEE Transactions on Applied Superconductivity 17 (2): 827-830. June 2007

Restoration of muscle strength in dystrophic muscle by Angiotensin-1-7 through inhibition of TGF-β signaling.
Acuna, M.J., Pessina, P., Olguin, H., Cabrera, D., Vio, C.P., Bader, M., Munoz-Canoves, P., Santos, R.A., Cabello-Verrugio, C. and Brandan, E.
Human Molecular Genetics 23 (5): 1237-1249. 1 March 2014

CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development.
Aherrahrou, R., Kulle, A.E., Alenina, N., Werner, R., Vens-Cappell, S., Bader, M., Schunkert, H., Erdmann, J. and Aherrahrou, Z.
Scientific Reports 10 (1): 8792. 29 May 2020

Angiotensin 1-7 prevents the excessive force loss resulting from 14- and 28-day denervation in mouse EDL and soleus muscle.
Albadrani, H., Ammar, T., Bader, M. and Renaud, J.M.
Journal of General Physiology 153 (12): e201912556. 6 December 2021

Angiotensin 1-7 increases fiber cross sectional area and force in juvenile mouse skeletal muscle.
Albadrani, H., Ammar, T., Rajgara, R., Bader, M., Wiper-Bergeron, N. and Renaud, J.M.
American Journal of Physiology Cell Physiology 323 (6): C1681-C1696. December 2022

Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation.
Albert-Weissenberger, C., Stetter, C., Meuth, S.G., Goebel, K., Bader, M., Siren, A.L. and Kleinschnitz, C.
Journal of Cerebral Blood Flow and Metabolism 32 (9): 1747-1756. September 2012

Specification and differentiation of serotonergic neurons.
Alenina, N., Bashammakh, S. and Bader, M.
Stem Cell Reviews 2 (1): 5-10. March 2006

Growth retardation and altered autonomic control in mice lacking brain serotonin.
Alenina, N., Kikic, D., Todiras, M., Mosienko, V., Qadri, F., Plehm, R., Boye, P., Vilianovitch, L., Sohr, R., Tenner, K., Hoertnagl, H. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (25): 10332-10337. 23 June 2009

The role of serotonin in adult hippocampal neurogenesis.
Alenina, N. and Klempin, F.
Behavioural Brain Research 277 : 49-57. 15 January 2015

Genetically altered animal models for Mas and Angiotensin-(1-7).
Alenina, N., Xu, P., Rentzsch, B., Patkin, E.L. and Bader, M.
Experimental Physiology 93 (5): 528-537. May 2008

Angiotensin-(1-7) and Mas: a brief history.
Alenina, N. and dos Santos, R.A.
In: The Protective Arm of the Renin Angiotensin System (RAS). Elsevier, Amsterdam, NL, 155-159. ISBN 9780128013649 2015

Transgenic animal models for the functional analysis of ACE2.
Alenina, N. and Bader, M.
In: Angiotensin : from the kidney to coronavirus. Molecular Mediators in Health and Disease: How Cells Communicate . Elsevier / Academic Press, London, 491-503. ISBN 978-0-323-99618-1 2023

ACE2 in brain physiology and pathophysiology: evidence from transgenic animal models.
Alenina, N. and Bader, M.
Neurochemical Research 44 (6): 1323-1329. June 2019

Genetic models.
Alenina, N. and Bader, M.
In: Angiotensin-(1-7) : a comprehensive review. Springer, Cham, 35-51. ISBN 978-3-030-22695-4 2019

Multiple non-coding exons and alternative splicing in the mouse Mas protooncogene.
Alenina, N., Böhme, I., Bader, M. and Walther, T.
Gene 568 (2): 155-164. 1 September 2015

Poor decision making and sociability impairment following central serotonin reduction in inducible TPH2-knockdown rats.
Alonso, L., Peeva, P., Fernández-del Valle Alquicira, T., Erdelyi, N., Gil Nolskog, Á., Bader, M., Winter, Y., Alenina, N. and Rivalan, M.
International Journal of Molecular Sciences 25 (9): 5003. May 2024

Constitutive depletion of brain serotonin differentially affects rats’ social and cognitive abilities.
Alonso, L., Peeva, P., Stasko, S., Bader, M., Alenina, N., Winter, Y. and Rivalan, M.
iScience 26 (2): 105998. 17 February 2023

Increased aortic intimal proliferation due to MasR deletion in vitro.
Alsaadon, H., Kruzliak, P., Smardencas, A., Hayes, A., Bader, M., Angus, P., Herath, C. and Zulli, A.
International Journal of Experimental Pathology 96 (3): 183-187. June 2015

Hemodynamic phenotyping of transgenic rats with ubiquitous expression of an angiotensin-(1-7)-producing fusion protein.
Alves, D.T., Mendes, L.F., Sampaio, W.O., Coimbra-Campos, L.M.C., Vieira, M.A.R., Ferreira, A.J., Martins, A.S., Popova, E., Todiras, M., Qadri, F., Alenina, N., Bader, M., Santos, R.A.S. and Campagnole-Santos, M.J.
Clinical Science 135 (18): 2197-2216. 8 September 2021

Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain.
Alves-Silva, T., Húngaro, T.G.R., Freitas-Lima, L.C., de Melo Arthur, G., Arruda, A.C., Santos, R.B., Oyama, L.M., Mori, M.A.S., Bader, M. and Araujo, R.C.
iScience 26 (12): 108409. 15 December 2023

Genetically altered animals in the study of the metabolic functions of peptide hormone systems.
Alves-da-Silva Mori, M., Bader, M. and Pesquero, J.B.
Current Opinion in Nephrology and Hypertension 17 (1): 11-17. January 2008

Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors.
Amado Costa, L., Oliveira Amaral, L.B., Mourão, F.A.G., Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Hormones and Behavior 163 : 105551. 27 April 2024

Vitamin D depletion aggravates hypertension and target-organ damage.
Andersen, L.B., Przybyl, L., Haase, N., von Versen-Höynck, F., Qadri, F., Jørgensen, J.S., Sorensen, G.L., Fruekilde, P., Poglitsch, M., Szijártó, I., Gollasch, M., Peters, J., Muller, D.N., Christesen, H.T. and Dechend, R.
Journal of the American Heart Association 4 (2): e001417. February 2015

Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder.
Andre, E., Gazzieri, D., Bardella, E., Ferreira, J., Mori, M.A., Saul, V.V., Bader, M., Calixto, J.B., De Giorgio, R., Corinaldesi, R., Geppetti, P. and Trevisani, M.
Gut 57 (5): 628-633. May 2008

Carbon-mixed dental cement for fixing fiber optic ferrules prevents visually triggered locomotive enhancement in mice upon optogenetic stimulation.
Araragi, N., Alenina, N. and Bader, M.
Heliyon 8 (1): e08692. January 2022

Tonin expression in the rat brain and tonin-mediated central production of angiotensin II.
Araujo, R.C., Lima, M.P., Lomez, E.S.L., Bader, M., Pesquero, J.B., Sumitani, M. and Pesquero, J.L.
Physiology & Behavior 76 (2): 327-333. 1 June 2002

Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function.
Araújo, R.C., Mori, M.A., Merino, V.F., Bascands, J.L., Schanstra, J.P., Zollner, R.L., Villela, C.A., Nakaie, C.R., Paiva, A.C., Pesquero, J.L., Bader, M. and Pesquero, J.B.
Biological Chemistry 387 (4): 431-436. April 2006

Role of kinin B1 and B2 receptors in the development of pilocarpine model of epilepsy.
Arganaraz, G.A., Perosa, S.R., Lencioni, E.C., Bader, M., Cavalheiro, E.A., da Graca Naffah-Mazzacoratti, M., Pesquero, J.B. and Silva, J.A.
Brain Research 1013 (1): 30-39. 1 January 2004

The synthesis and distribution of the kinin B1 and B2 receptors are modified in the hippocampus of rats submitted to pilocarpine model of epilepsy.
Arganaraz, G.A., Silva, J.A., Perosa, S.R., Pessoa, L.G., Carvalho, F.F., Bascands, J.L., Bader, M., Trindade, E.D., Amado, D., Cavalheiro, E.A., Pesquero, J.B. and Naffah-Mazzacoratti, M.D.
Brain Research 1006 (1): 114-125. 1 January 2004

Kinin B1 receptor modulates mitochondrial activity responsivity in fasting and voluntary exercise.
Arruda, A.C., Budu, A., de Menezes, T.N., Bader, M., Araujo, R.C. and Freitas-Lima, L.C.
Life Sciences 309 : 121034. 15 November 2022

Pioglitazone prevents capillary rarefaction in streptozotocin-diabetic rats independently of glucose control and vascular endothelial growth factor expression.
Ashoff, A., Qadri, F., Eggers, R., Joehren, O., Raasch, W. and Dendorfer, A.
Journal of Vascular Research 49 (3): 260-266. May 2012

Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema.
Austinat, M., Braeuninger, S., Pesquero, J.B., Brede, M., Bader, M., Stoll, G., Renne, T. and Kleinschnitz, C.
Stroke 40 (1): 285-293. January 2009

Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G., Bartolomaeus, H., Rauch, A., Chen, C.Y., N'Diaye, G., Löber, U., Bartolomaeus, T.U.P., Fritsche-Guenther, R., Rodrigues, A.F., Yarritu, A., Zhong, C., Fei, L., Tsvetkov, D., Todiras, M., Park, J.K., Markó, L., Maifeld, A., Patzak, A., Bader, M., Kempa, S., Kirwan, J.A., Forslund, S.K., Müller, D.N. and Wilck, N.
Cardiovascular Research 119 (6): 1441-1452. May 2023

GPER activation attenuates cardiac dysfunction by upregulating the SIRT1/3-AMPK-UCP2 pathway in postmenopausal diabetic rats.
Azizian, H., Farhadi, Z., Bader, M., Ghalenoei, J.A., Ghafari, M.A. and Mahmoodzadeh, S.
PLoS ONE 18 (12): e0293630. 22 December 2023

Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice.
Bachmann, S., Mutig, K., Bates, J., Welker, P., Geist, B., Gross, V., Luft, F.C., Alenina, N., Bader, M., Thiele, B.J., Prasadan, K., Raffi, H.S. and Kumar, S.
American Journal of Physiology Renal Physiology 288 (3): F559-F567. 1 January 2005

Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genes.
Bachvarov, D., Bachvarova, M., Koumangaye, R., Klein, J., Pesquero, J.B., Neau, E., Bader, M., Schanstra, J.P. and Bascands, J.L.
Biological Chemistry 387 (1): 15-22. January 2006

ACE2, angiotensin-(1-7), and Mas: the other side of the coin.
Bader, M.
Pfluegers Archiv European Journal of Physiology 465 (1): 79-85. January 2013

Kinins.
Bader, M.
de Gruyter. ISBN 978-3-11-025234-7 November 2011

Kinins: History and outlook.
Bader, M.
In: Kinins. de Gruyter, 1-6. ISBN 978-3-11-025234-7 November 2011

Rat models of cardiovascular diseases.
Bader, M.
Methods in Molecular Biology 597 : 403-414. 2010

Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy.
Bader, M.
Annual Review of Pharmacology and Toxicology 50 : 439-65. 2010

Kallikrein-kinin system in neovascularization.
Bader, M.
Arteriosclerosis Thrombosis and Vascular Biology 29 (5): 617-619. May 2009

Highlights of the 13th Annual Meeting of the European Council for Cardiovascular Research. 13th Annual Meeting of the European Council for Cardiovascular Research (ECCR). Nice, France, 10-12 October, 2008.
Bader, M.
Future Cardiology 5 (1): 23-25. January 2009

Preface.
Bader, M.
Cardiovascular Hormone Systems : xvii-xviii. 10 September 2008

Serotonin.
Bader, M.
In: Cardiovascular Hormone Systems. Wiley-Blackwell, 209-231. ISBN 9783527319206 10 September 2008

KININ2007: Comeback for kinins.
Bader, M.
International Immunopharmacology 8 (2): 133-134. February 2008

The second life of the (pro)renin receptor.
Bader, M.
Journal of the Renin Angiotensin Aldosterone System 8 (4): 205-208. December 2007

Renin.
Bader, M.
In: xPharm: The Comprehensive Pharmacology Reference. UNSPECIFIED, 1-10. ISBN 978-0-08-055232-3 2007

Mouse knockout models of hypertension.
Bader, M.
In: Hypertension: Methods and Protocols. Methods in Molecular Medicine ; 108 . Humana Press, Totowa (NJ), 17-32. ISBN 1543-1894 25 October 2004

Role of local renin angiotensin systems in cardiac damage.
Bader, M.
In: Renin Angiotensin System and the Heart. John Wiley & Sons, 47-62. ISBN 9780470862926 2004

Mas and its related G protein-coupled receptors, Mrgprs.
Bader, M., Alenina, N., Andrade-Navarro, M.A. and Santos, R.A.
Pharmacological Reviews 66 (4): 1080-1105. October 2014

Grundlagen der molekularen Zellbiologie.
Bader, M. and Behrens, J.
In: Grundlagen der Molekularen Medizin. Molekulare Medizin . Springer, Berlin [u.a.], 3-53. ISBN 3-540-43207-8 1 January 2003

Update on tissue renin-angiotensin systems.
Bader, M. and Ganten, D.
Journal of Molecular Medicine 86 (6): 615-621. June 2008

Transgenics of the RAS.
Bader, M. and Ganten, D.
In: Angiotensin, Vol. 1. Handbook of Experimental Pharmacology ; 163, 1 . Springer, Berlin [u.a.], 229-249. ISBN 3-540-40640-9 1 January 2004

New therapeutic pathways in the RAS.
Bader, M., Santos, R.A., Unger, T. and Steckelings, U.M.
Journal of the Renin Angiotensin Aldosterone System 13 (4): 505-508. December 2012

Renin-angiotensin-aldosterone system.
Bader, M.
In: Encyclopedia of Molecular Pharmacology : Third Edition. Springer, Cham, 1353-1358. ISBN 978-3-030-57400-0 2021

ACE2 - das missbrauchte Multitalent [ACE2 - the hijacked all-rounder].
Bader, M.
Nephrologe 15 (6): 375-380. November 2020

Inhibition of serotonin synthesis: a novel therapeutic paradigm.
Bader, M.
Pharmacology & Therapeutics 205 : 107423. January 2020

Serotonylation: serotonin signaling and epigenetics.
Bader, M.
Frontiers in Molecular Neuroscience 12 : 288. 21 November 2019

Of mice and renin.
Bader, M.
Hypertension 70 (1): 35-37. July 2017

The Meaning of Mas.
Bader, M., Alenina, N., Young, D., Santos, R.A.S. and Touyz, R.M.
Hypertension 72 (5): 1072-1075. November 2018

Alternative renin-angiotensin system.
Bader, M., Muscha Steckelings, U., Alenina, N., Santos, R.A.S. and Ferrario, C.M.
Hypertension 81 (5): 964-976. May 2024

Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same.
Max-Delbrück-Centrum für Molekulare Medizin.
201615552556. 22 February 2018

Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same.
Max-Delbrück-Centrum für Molekulare Medizin.
WO/2016/135199. 1 September 2016

ACE2, a multifunctional protein - from cardiovascular regulation to COVID-19.
Bader, M., Turner, A.J. and Alenina, N.
Clinical Science 134 (23): 3229-3232. 11 December 2020

Role of the local renin-angiotensin system in cardiac damage: a minireview focussing on transgenic animal models.
Bader, M.
Journal of Molecular and Cellular Cardiology 34 (11): 1455-1462. November 2002

hnRNP-K targets open chromatin in mouse embryonic stem cells in concert with multiple regulators.
Bakhmet, E.I., Nazarov, I.B., Gazizova, A.R., Vorobyeva, N.E., Kuzmin, A.A., Gordeev, M.N., Sinenko, S.A., Aksenov, N. D., Artamonova, T.O., Khodorkovskii, M.A., Alenina, N., Onichtchouk, D., Wu, G., Schöler, H.R. and Tomilin, A.N.
Stem Cells 37 (8): 1018-1029. August 2019

Stress worsens endothelial function and ischemic stroke via glucocorticoids.
Balkaya, M., Prinz, V., Custodis, F., Gertz, K., Kronenberg, G., Kroeber, J., Fink, K., Plehm, R., Gass, P., Laufs, U. and Endres, M.
Stroke 42 (11): 3258-3264. November 2011

Angiotensin.
Baltatu, O. and Bader, M.
In: Encyclopedia of Stress. UNSPECIFIED, 182-186. ISBN 978-0-12-373947-6 2007

Brain renin-angiotensin system - Lessons from functional genomics.
Baltatu, O. and Bader, M.
Neuroendocrinology 78 (5): 253-259. November 2003

Genetic targeting of the brain renin-angiotensin system in transgenic rats: Impact on stress-induced renin release.
Baltatu, O., Campos, L.A. and Bader, M.
Acta Physiologica Scandinavica 181 (4): 579-584. 1 August 2004

Abolition of end-organ damage by antiandrogen treatment in female hypertensive transgenic rats.
Baltatu, O., Cayla, C., Iliescu, R., Andreev, D. and Bader, M.
Hypertension 41 (3): 830-833. March 2003

Local renin angiotensin system and the brain-A continuous quest for knowledge.
Baltatu, O.C., Campos, L.A. and Bader, M.
Peptides 32 (5): 1083-1086. May 2011

Avosentan is protective in hypertensive nephropathy at doses not causing fluid retention.
Baltatu, O.C., Zaugg, C.E., Schumacher, C., Louie, P., Campos, L.A. and Bader, M.
Pharmacological Research 80 : 9-13. February 2014

Transcriptional regulation of the rat bradykinin B2 receptor gene: Identification of a silencer element.
Baptista, H.A., Avellar, M.C.W., Araujo, R.C., Pesquero, J.L., Schanstra, J.P., Bascands, J.L., Esteve, J.P., Paiva, A.C.M., Bader, M. and Pesquero, J.B.
Molecular Pharmacology 62 (6): 1344-1355. 1 December 2002

Induction and analysis of cardiac hypertrophy in transgenic animal models.
Barbosa, M.E., Alenina, N. and Bader, M.
In: Molecular cardiology: Methods and protocols. Methods in Molecular Medicine ; 112 . Humana Press, Totowa, NJ, 339-352. ISBN 1-58829-363-7 1 January 2005

Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats.
Barmashenko, G., Buttgereit, J., Herring, N., Bader, M., Oezcelik, C., Manahan-Vaughan, D. and Braunewell, K.H.
Frontiers in Molecular Neuroscience 7 : 95. 1 December 2014

Altered glucose homeostasis and hepatic function in obese mice deficient for both kinin receptor genes.
Barros, C.C., Haro, A., Russo, F.J.V.P., Schadock, I., Almeida, S.S., Ribeiro, R.A., Vanzela, E.C., Lanzoni, V.P., Barros, F.C., Moraes, M.R., Mori, M.A., Bacurau, R.F.P., Wurtele, M., Boschero, A.C., Carneiro, E.M., Bader, M., Pesquero, J.B. and Araujo, R.C.
PLoS ONE 7 (7): e40573. 19 July 2012

Chronic overexpression of bradykinin in kidney causes polyuria and cardiac hypertrophy.
Barros, C.C., Schadock, I., Sihn, G., Rother, F., Xu, P., Popova, E., Lapidus, I., Plehm, R., Heuser, A., Todiras, M., Bachmann, S., Alenina, N., Araujo, R.C., Pesquero, J.B. and Bader, M.
Frontiers in Medicine 5 : 338. December 2018

Renoprotective effects of AVE0991, a nonpeptide Mas receptor agonist, in experimental acute renal injury.
Barroso, L.C., Silveira, K.D., Lima, C.X., Borges, V., Bader, M., Rachid, M., Souza Santos, R.A., Souza, D.G., Simoes e Silva, A.C. and Teixeira, M.M.
International Journal of Hypertension 2012 : 808726. 2012

Endothelium dependent expression and underlying mechanisms of des-Arg(9)-bradykinin-induced B(1)R-mediated vasoconstriction in rat portal vein.
Basei, F.L., Cabrini, D.A., Figueiredo, C.P., Forner, S., Hara, D.B., Nascimento, A.F.Z., Ceravolo, G.S., Carvalho, M.H.C., Bader, M., Medeiros, R. and Calixto, J.B.
Peptides 37 (2): 216-224. October 2012

The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.
Batalha, V.L., Ferreira, D.G., Coelho, J.E., Valadas, J.S., Gomes, R., Temido-Ferreira, M., Shmidt, T., Baqi, Y., Buée, L., Müller, C.E., Hamdane, M., Outeiro, T.F., Bader, M., Meijsing, S.H., Sadri-Vakili, G., Blum, D. and Lopes, L.V.
Scientific Reports 6 : 31493. 11 August 2016

Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor.
Batenburg, W.W., Krop, M., Garrelds, I.M., de Vries, R., de Bruin, R.J.A., Burckle, C.A., Mueller, D.N., Bader, M., Nguyen, G. and Danser, A.H.J.
Journal of Hypertension 25 (12): 2441-2453. December 2007

Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells.
Batenburg, W.W., de Bruin, R.J., van Gool, J.M., Mueller, D.N., Bader, M., Nguyen, G. and Danser, A.H.
Arteriosclerosis Thrombosis and Vascular Biology 28 (6): 1151-1157. June 2008

ACE activity is modulated by the enzyme alpha-galactosidase A.
Batista, E.C., Carvalho, L.R., Casarini, D.E., Carmona, A.K., Dos Santos, E.L., da Silva, E.D., Dos Santos, R.A., Nakaie, C.R., Rojas, M.V., de Oliveira, S.M., Bader, M., D'Almeida, V., Martins, A.M., de Picoly Souza, K. and Pesquero, J.B.
Journal of Molecular Medicine 89 (1): 65-74. January 2011

Role of endothelial kinin B(1) receptor on the membrane potential of transgenic rat aorta.
Batista, C., Sales, V.M., Merino, V.F., Bader, M., Feres, T. and Pesquero, J.B.
Physiological Research 71 (4): 477-487. August 2022

Paternal exercise protects against liver steatosis in the male offspring of mice submitted to high fat diet.
Batista, R.O., Budu, A., Alves-Silva, T., Arakaki, A.M., Gregnani, M.F.S., Rodrigues Húngaro, T.G., Burgos-Silva, M., Wasinski, F., Lanzoni, V.P., Camara, N.O.S., Oyama, L.M., Bader, M. and Araújo, R.C.
Life Sciences 263 : 118583. 15 December 2020

Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity.
Batlle, D., Monteil, V., Garreta, E., Hassler, L., Wysocki, J., Chandar, V., Schwartz, R.E., Mirazimi, A., Montserrat, N., Bader, M. and Penninger, J.M.
Cell 185 (11): 1837-1839. 26 May 2022

Elastase-2, a tissue alternative pathway for angiotensin II generation, plays a role in circulatory sympathovagal balance in mice.
Becari, C., Durand, M.T., Guimaraes, A.O., Lataro, R.M., Prado, C.M., de Oliveira, M., Candido, S.C.O., Pais, P., Ribeiro, M.S., Bader, M., Pesquero, J.B., Salgado, M.C.O. and Salgado, H.C.
Frontiers in Physiology 8 : 170. 23 March 2017

Impact of genetic deletion of MrgD or Mas receptors in depressive-like behaviour in mice.
Becari, L., Fonseca, M.L.A., Gonçalves, S.C.A, Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Acta Neuropsychiatrica 35 (1): 27-34. February 2023

Brain serotonin deficiency leads to social communication deficits in mice.
Beis, D., Holzwarth, K., Flinders, M., Mosienko, V., Bader, M., Wöhr, M. and Alenina, N.
Biology Letters 11 (3): 20150057. March 2015

Crosstalk between the renin-angiotensin, complement and kallikrein-kinin systems in inflammation.
Bekassy, Z., Lopatko Fagerström, I., Bader, M. and Karpman, D.
Nature Reviews Immunology 22 (7): 411-428. July 2022

Axonal transcription factors signal retrogradely in lesioned peripheral nerve.
Ben-Yaakov, K., Dagan, S.Y., Segal-Ruder, Y., Shalem, O., Vuppalanchi, D., Willis, D.E., Yudin, D., Rishal, I., Rother, F., Bader, M., Blesch, A., Pilpel, Y., Twiss, J.L. and Fainzilber, M.
EMBO Journal 31 (6): 1350-1363. 13 January 2012

Decreased hepatic gluconeogenesis in transgenic rats with increased circulating angiotensin-(1-7).
Bilman, V., Mares-Guia, L., Nadu, A.P., Bader, M., Campagnole-Santos, M.J., Santos, R.A.S. and Santos, S.H.S.
Peptides 37 (2): 247-251. October 2012

Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization.
Binas, B., Danneberg, H., McWhir, J., Mullins, L. and Clark, A.J.
FASEB Journal 13 (8): 805-812. May 1999

Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J., Neukam, M., Tattikota, S.G., Qadri, F., Puchkov, D., Willmes, D.M., Wurmsee, S., Geisberger, S., Dechend, R., Raile, K., Kurth, T., Nguyen, G., Poy, M.N., Solimena, M., Muller, D.N. and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116 (40): 19983-19988. 1 October 2019

Effect of angiotensin(1-7) on heart function in an experimental rat model of obesity.
Blanke, K., Schlegel, F., Raasch, W., Bader, M., Dähnert, I., Dhein, S. and Salameh, A.
Frontiers in Physiology 6 : 392. 21 December 2015

Calcineurin inhibitor cyclosporine a activates renal Na-K-Cl cotransporters via local and systemic mechanisms.
Blankenstein, K.I., Borschewski, A., Labes, R., Paliege, A., Boldt, C., McCormick, J.A., Ellison, D.H., Bader, M., Bachmann, S. and Mutig, K.
American Journal of Physiology Renal Physiology 312 (3): F489-F501. 2 March 2017

Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation.
Bocciardi, R., Giorda, R., Buttgereit, J., Gimelli, S., Divizia, M.T., Beri, S., Garofalo, S., Tavella, S., Lerone, M., Zuffardi, O., Bader, M., Ravazzolo, R. and Gimelli, G.
Human Mutation 28 (7): 724-731. July 2007

Blood pressure and renin-angiotensin system resetting in transgenic rats with elevated plasma Val5-angiotensinogen.
Bohlender, J., Bader, M., Menard, J. and Nussberger, J.
Journal of Hypertension 30 (8): 1597-1605. August 2012

Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N., Bader, M., Willnow, T.E., Wiedenmann, B. and Sigal, M.
Frontiers in Endocrinology 15 : 1331231. 17 April 2024

Tonin in rat heart with experimental hypertrophy.
Borges, J.C., Silva, J.A., Gomes, M.A., Lomez, E.S.L., Leite, K.M., Araujo, R.C., Bader, M., Pesquero, J.B. and Pesquero, J.L.
American Journal of Physiology Heart and Circulatory Physiology 284 (6): H2263-H2268. 1 June 2003

The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons.
Borroto-Escuela, D.O., Ferraro, L., Beggiato, S., Narváez, M., Fores-Pons, R., Alvarez-Contino, J.E., Wydra, K., Frankowska, M., Bader, M., Filip, M. and Fuxe, K.
Pharmacological Reports 73 (4): 1096-1108. August 2021

Altered regional blood flow distribution in Mas-deficient mice.
Botelho-Santos, G.A., Bader, M., Alenina, N. and Santos, R.A.
Therapeutic Advances in Cardiovascular Disease 6 (5): 201-211. October 2012

Expression of an angiotensin-(1-7)-producing fusion protein in rats induced marked changes in regional vascular resistance.
Botelho-Santos, G.A., Sampaio, W.O., Reudelhuber, T.L., Bader, M., Campagnole-Santos, M.J. and Santos, R.A.
American Journal of Physiology Heart and Circulatory Physiology 292 (5): H2485-H2490. 1 May 2007

Functional autoantibodies against G protein-coupled receptors in hepatic and pulmonary hypertensions in human schistosomiasis.
Botoni, F.A., Lambertucci, J.R., Santos, R.A.S., Müller, J., Talvani, A. and Wallukat, G.
Frontiers in Immunology 15 : 1404384. 17 June 2024

ATP6AP2 over-expression causes morphological alterations in the hippocampus and in hippocampus-related behaviour.
Bracke, A., Schäfer, S., von Bohlen und Halbach, V., Klempin, F., Bente, K., Bracke, K., Staar, D., van den Brandt, J., Harzsch, S., Bader, M., Wenzel, U.O., Peters, J. and von Bohlen und Halbach, O.
Brain Structure & Function 223 (5): 2287-2302. June 2018

Cardiovascular peptide hormones - special edition.
Braga, T.V., Mervaala, E., Santos, R. and Bader, M.
Peptides 167 : 171062. September 2023

Rat embryonic stem cells: a progress report.
Brenin, D.R., Look, J., Bader, M., Hübner, N., Levan, G. and Iannaccone, P.
Transplantation Proceedings 29 : 1761-1765. 1 January 1997

TPH2 deficiency influences neuroplastic mechanisms and alters the response to an acute stress in a sex specific manner.
Brivio, P., Sbrini, G., Peeva, P., Todiras, M., Bader, M., Alenina, N. and Calabrese, F.
Frontiers in Molecular Neuroscience 11 : 389. 30 October 2018

Impairment of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension.
Buergelova, M., Vanourkova, Z., Thumova, M., Dvorak, P., Opocensky, M., Kramer, H.J., Zelizko, M., Maly, J., Bader, M. and Cervenka, L.
Journal of Hypertension 27 (10): 1988-2000. October 2009

Prorenin and its ancient receptor.
Burckle, C. and Bader, M.
Hypertension 48 (4): 549-551. October 2006

Elevated blood pressure and heart rate in human renin receptor transgenic rats.
Burckle, C.A., Danser, A.H.J., Mueller, D.N., Garrelds, I.M., Gasc, J.M., Popova, E., Plehm, R., Peters, J., Bader, M. and Nguyen, G.
Hypertension 47 (3): 552-556. March 2006

Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies.
Burghi, V., Fernández, N.C., Gándola, Y.B., Piazza, V.G., Quiroga, D.T., Guilhen Mario, E., Felix Braga, J., Bader, M., Santos, R.A.S., Dominici, F.P. and Munoz, M.C.
PLoS ONE 12 (8): e0183278. 16 August 2017

Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M., Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M., Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A., Scheidereit, C., Butter, C., Felix, S.B., Otto, O., Luft, F.C., Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12 (6): 1653-1668. December 2021

Visinin-like protein 1 regulates natriuretic peptide receptor B in the heart.
Buttgereit, J., Qadri, F., Monti, J., Langenickel, T.H., Dietz, R., Braunewell, K.H. and Bader, M.
Regulatory Peptides 161 (1-3): 51-57. 9 April 2010

C-type natriuretic peptide and NPR-B signalling inhibits cardiac sympathetic neurotransmission and autonomic function.
Buttgereit, J., Shanks, J., Li, D., Hao, G., Athwal, A., Langenickel, T.H., Wright, H., da Costa Goncalves, A.C., Monti, J., Plehm, R., Popova, E., Qadri, F., Lapidus, I., Ryan, B., Özcelik, C., Paterson, D.J., Bader, M. and Herring, N.
Cardiovascular Research 112 (3): 637-644. December 2016

Baroreflex control of heart rate and renal sympathetic nerve activity in rats with low brain angiotensinogen.
Caligiorne, S.M., Silva, A.Q., Fontes, M.A., Silva, J.R., Baltatu, O.C., Bader, M., Santos, R.A. and Campagnole-Santos, M.J.
Neuropeptides 42 (2): 159-168. April 2008

Brain renin-angiotensin system in hypertension, cardiac hypertrophy, and heart failure.
Campos, L.A., Bader, M. and Baltatu, O.C.
Frontiers in Physiology 2 : 115. 3 January 2012

The Angiotensin-melatonin axis.
Campos, L.A., Cipolla-Neto, J., Amaral, F.G., Michelini, L.C., Bader, M. and Baltatu, O.C.
International Journal of Hypertension 2013 : 521783. 2013

Differential regulation of central vasopressin receptors in transgenic rats with low brain angiotensinogen.
Campos, L.A., Couto, A.S., Iliescu, R., Santos, J.A., Santos, R.A.S., Ganten, D., Campagnole-Santos, M.J., Bader, M. and Baltatu, O.
Regulatory Peptides 119 (3): 177-182. 15 July 2004

Enhanced isoproterenol-induced cardiac hypertrophy in transgenic rats with low brain angiotensinogen.
Campos, L.A., Iliescu, R., Fontes, M.A.P., Schlegel, W.P., Bader, M. and Baltatu, O.C.
American Journal of Physiology Heart and Circulatory Physiology 291 (5): H2371-H2376. 1 November 2006

Altered circadian rhythm reentrainment to light phase shifts in rats with low brain angiotensinogen.
Campos, L.A., Plehm, R., Cipolla-Neto, J., Bader, M. and Baltatu, O.C.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 290 (4): R1122-R1127. 1 April 2006

Increased blood pressure and water intake in transgenic mice expressing rat tonin in the brain.
Cardoso, C.C., Alenina, N., Ferreira, A.J., Qadri, F., Lima, M.P., Gross, V., Todiras, M., Pesquero, J.B., Pesquero, J.L. and Bader, M.
Biological Chemistry 391 (4): 435-441. April 2010

Functional expression of angiotensinogen depends on splicing enhancers in exon 2.
Cardoso, C.C., Cabrini, D.A., May, M., Bhagat, C.S., Eleno, N., Cayla, C., Walther, T. and Bader, M.
Molecular and Cellular Endocrinology 332 (1-2): 228-233. 30 January 2011

Structure and expression of two kininogen genes in mice.
Cardoso, C.C., Garrett, T., Cayla, C., Meneton, P., Pesquero, J.B. and Bader, M.
Biological Chemistry 385 (3-4): 295-301. 1 January 2004

Functional domains of human tryptophan hydroxylase 2 (hTPH2).
Carkaci-Salli, N., Flanagan, J.M., Martz, M.K., Salli, U., Walther, D.J., Bader, M. and Vrana, K.E.
Journal of Biological Chemistry 281 (38): 28105-28112. 22 September 2006

Serotonin regulates prostate growth through androgen receptor modulation.
Carvalho-Dias, E., Miranda, A., Martinho, O., Mota, P., Costa, A., Nogueira-Silva, C., Moura, R.S., Alenina, N., Bader, M., Autorino, R., Lima, E. and Correia-Pinto, J.
Scientific Reports 7 (1): 15428. 13 November 2017

Bradykinin inhibits hepatic gluconeogenesis in obese mice.
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Mice deficient for both kinin receptors are normotensive and protected from endotoxin- induced hypotension.
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Brown adipose tissue transcriptome unveils an important role of the Beta-alanine/alamandine receptor, MrgD, in metabolism.
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Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome.
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Oxidative RNA damage in the pathogenesis and treatment of type 2 diabetes.
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Karyopherin alpha 1 regulates satellite cell proliferation and survival by modulating nuclear import.
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Characterization of trophoblast and extraembryonic endoderm cell lineages derived from rat preimplantation embryos.
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Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.
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Overexpression of adenosine A2A receptors in rats: effects on depression, locomotion, and anxiety.
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Transforming growth factor type-β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular dystrophies.
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A role of the (pro)renin receptor in neuronal cell differentiation.
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Transient inflammatory response induced by apoptotic cells is an important mediator of melanoma cell engraftment and growth.
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Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function.
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Short-term western diet aggravates non-alcoholic fatty liver disease (NAFLD) with portal hypertension in TGR(mREN2)27 rats.
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Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models.
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Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.
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Lrp5 functions in bone to regulate bone mass.
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Myogenic vasoconstriction requires canonical Gq/11 signaling of the angiotensin II type 1a receptor in the murine vasculature.
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The antiobese effect of AT1 receptor blockade is augmented in mice lacking Mas.
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Neuronal adenosine A(2A) receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease.
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Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
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Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.
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Short-term cardiovascular physical programme ameliorates arterial stiffness and decreases oxidative stress in women with metabolic syndrome.
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Angiotensin-converting enzyme inhibitor protects against cisplatin nephrotoxicity by modulating kinin B1 receptor expression and aminopeptidase P activity in mice.
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Glucagon-producing cells are increased in Mas-deficient mice.
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Expert Opinion on Therapeutic Patents 22 (5): 567-574. May 2012

Attenuation of isoproterenol-induced cardiac fibrosis in transgenic rats harboring an angiotensin-(1-7)-producing fusion protein in the heart.
Ferreira, A.J., Castro, C.H., Guatimosim, S., Almeida, P.W.M., Gomes, E.R.M., Dias-Peixoto, M.F., Alves, M.N.A., Fagundes-Moura, C.R., Rentzsch, B., Gava, E., Almeida, A.P., Guimaraes, A.M., Kitten, G.T., Reudelhuber, T., Bader, M. and Santos, R.A.S.
Therapeutic Advances in Cardiovascular Disease 4 (2): 83-96. April 2010

Renal function in transgenic rats expressing an angiotensin-(1-7)-producing fusion protein.
Ferreira, A.J., Pinheiro, S.V.B., Castro, C.H., Silva, G.A.B., Simoes E Silva, A.C., Almeida, A.P., Bader, M., Rentzsch, B., Reudelhuber, T.L. and Santos, R.A.S.
Regulatory Peptides 137 (3): 128-133. 10 December 2006

The role of kinin B(1) receptors in the nociception produced by peripheral protein kinase C activation in mice.
Ferreira, J., Triches, K.M., Medeiros, R., Cabrini, D.A., Mori, M.A.S., Pesquero, J.B., Bader, M. and Calixto, J.B.
Neuropharmacology 54 (3): 597-604. March 2008

Reduced nerve injury-induced neuropathic pain in kinin B1 receptor knock-out mice.
Ferreira, J., Beirith, A., Mori, M.A., Araújo, R.C., Bader, M., Pesquero, J.B. and Calixto, J.B.
Journal of Neuroscience 25 (9): 2405-2412. 2 March 2005

Role of kinin receptors in skin pigmentation.
Ferreira, J.C.P., Soley, B.S., Pawloski, P.L., Moreira, C.G., Pesquero, J.B., Bader, M., Calixto, J.B., Cabrini, D.A. and Otuki, M.F.
European Journal of Pharmacology 973 : 176537. 15 June 2024

Regulation of karyopherin alpha1 and nuclear import by mammalian target of rapamycin.
Fielhaber, J.A., Tan, J., Joung, K.B., Attias, O., Huegel, S., Bader, M., Roux, P.P. and Kristof, A.S.
Journal of Biological Chemistry 287 (18): 14325-14335. 27 April 2012

The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule.
Figueiredo, M., Daryadel, A., Sihn, G., Müller, D.N., Popova, E., Rouselle, A., Nguyen, G., Bader, M. and Wagner, C.A.
Pflugers Archiv 473 : 1229-1246. August 2021

Behavioral evidence for the significance of serotoninergic (5-HT) receptors in cocaine addiction.
Filip, M., Alenina, N., Bader, M. and Przegalinski, E.
Addiction Biology 15 (3): 227-249. July 2010

Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system.
Filip, M. and Bader, M.
Pharmacological Reports 61 (5): 761-777. September 2009

Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension.
Fischer, R., Dechend, R., Qadri, F., Markovic, M., Feldt, S., Herse, F., Park, J.K., Gapelyuk, A., Schwarz, I., Zacharzowsky, U.B., Plehm, R., Safak, E., Heuser, A., Schirdewan, A., Luft, F.C., Schunck, W.H. and Mueller, D.N.
Hypertension 51 (2): 540-546. February 2008

Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells.
Fishman, V.S., Shnayder, T.A., Orishchenko, K.E., Bader, M., Alenina, N. and Serov, O.L.
Cell Cycle 14 (8): 1188-1196. 15 April 2015

A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation.
Folkesson, R., Malkiewicz, K., Kloskowska, E., Nilsson, T., Popova, E., Bogdanovic, N., Ganten, U., Ganten, D., Bader, M., Winblad, B. and Benedikz, E.
Biochemical and Biophysical Research Communications 358 (3): 777-782. 6 July 2007

The role of receptor MAS in microglia-driven retinal vascular development.
Foulquier, S., Caolo, V., Swennen, G., Milanova, I., Reinhold, S., Recarti, C., Alenina, N., Bader, M., Steckelings, U M., Vanmierlo, T., Post, M.J., Jones, E.A., van Oostenbrugge, R.J. and Unger, T.
Angiogenesis 22 (4): 481-189. November 2019

Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D., Luft, F.C., Bader, M., Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90 (5): 495-508. May 2012

An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect.
Fraga-Silva, R.A., Costa-Fraga, F.P., Sousa, F.B., Alenina, N., Bader, M., Sinisterra, R.D. and Santos, R.A.
Clinics 66 (5): 837-841. 2011

The antithrombotic effect of angiotensin-(1-7) involves mas-mediated NO release from platelets.
Fraga-Silva, R.A., Pinheiro, S.V., Goncalves, A.C., Alenina, N., Bader, M. and Santos, R.A.
Molecular Medicine 14 (1-2): 28-35. January 2008

Effects of bradykinin B2 receptor ablation from tyrosine hydroxylase cells on behavioral and motor aspects in male and female mice.
Franco, T.M., Tavares, M.R., Novaes, L.S., Munhoz, C.D., Peixoto-Santos, J.E., Araujo, R.C., Donato, J., Bader, M. and Wasinski, F.
International Journal of Molecular Sciences 25 (3): 1490. 25 January 2024

Absence of diabetic hyperalgesia in bradykinin B1 receptor-knockout mice.
Gabra, B.H., Merino, V.F., Bader, M., Pesquero, J.B. and Sirois, P.
Regulatory Peptides 127 (1-3): 245-248. 1 January 2005

Importin-α7 is involved in the formation of Ebola virus inclusion bodies but is not essential for pathogenicity in mice.
Gabriel, G., Feldmann, F., Reimer, R., Thiele, S., Fischer, M., Hartmann, E., Bader, M., Ebihara, H., Hoenen, T. and Feldmann, H.
Journal of Infectious Diseases 212 (Suppl 2): S316-S321. 1 October 2015

Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus.
Gabriel, G., Klingel, K., Otte, A., Thiele, S., Hudjetz, B., Arman-Kalcek, G., Sauter, M., Shmidt, T., Rother, F., Baumgarte, S., Keiner, B., Hartmann, E., Bader, M., Brownlee, G.G., Fodor, E. and Klenk, H.D.
Nature Communications 2 (1): 156. January 2011

An old couple: the renin-angiotensin system (RAS) and the Journal of Molecular Medicine (JMolMed).
Ganten, D., Bader, M. and Juergensen, J.S.
Journal of Molecular Medicine 86 (6): 609-610. June 2008

Cardiac magnetic field mapping quantified by Kullback-Leibler entropy detects patients with coronary artery disease.
Gapelyuk, A., Schirdewan, A., Fischer, R. and Wessel, N.
Physiological Measurement 31 (10): 1345-1354. October 2010

Angiotensin-(1-7) receptor Mas is an essential modulator of extracellular matrix protein expression in the heart.
Gava, E., de Castro, C.H., Ferreira, A.J., Colleta, H., Melo, M.B., Alenina, N., Bader, M., Oliveira, L.A., Santos, R.A.S. and Kitten, G.T.
Regulatory Peptides 175 (1-3): 30-42. 10 April 2012

Priming of LTP in amygdala and hippocampus by prior paired pulse facilitation paradigm in mice lacking brain serotonin.
Gebhardt, C., Mosienko, V., Alenina, N. and Albrecht, D.
Hippocampus 29 (7): 610-618. July 2019

Large-scale mapping of mutations affecting zebrafish development.
Geisler, R., Rauch, G.J., Geiger-Rudolph, S., Albrecht, A., van Bebber, F., Berger, A., Busch-Nentwich, E., Dahm, R., Dekens, M.P., Dooley, C., Elli, A.F., Gehring, I., Geiger, H., Geisler, M., Glaser, S., Holley, S., Huber, M., Kerr, A., Kirn, A., Knirsch, M., Konantz, M., Kuechler, A.M., Maderspacher, F., Neuhauss, S.C., Nicolson, T., Ober, E.A., Praeg, E., Ray, R., Rentzsch, B., Rick, J.M., Rief, E., Schauerte, H.E., Schepp, C.P., Schoenberger, U., Schonthaler, H.B., Seiler, C., Sidi, S., Soellner, C., Wehner, A., Weiler, C. and Nuesslein-Volhard, C.
BMC Genomics 8 : 11. 9 January 2007

SDF-1alpha as a therapeutic stem cell homing factor in myocardial infarction.
Ghadge, S.K., Muehlstedt, S., Oezcelik, C. and Bader, M.
Pharmacology & Therapeutics 129 (1): 97-108. January 2011

Working memory deficits in transgenic rats overexpressing human adenosine A(2A) receptors in the brain.
Gimenez-Llort, L., Schiffmann, S.N., Shmidt, T., Canela, L., Camon, L., Wassholm, M., Canals, M., Terasmaa, A., Fernandez-Teruel, A., Tobena, A., Popova, E., Ferre, S., Agnati, L., Ciruela, F., Martinez, E., Scheel-Kruger, J., Lluis, C., Franco, R., Fuxe, K. and Bader, M.
Neurobiology of Learning Memory 87 (1): 42-56. January 2007

Cytoplasmic fatty acid-binding protein facilitates fatty acid utilization by skeletal muscle.
Glatz, J.F.C., Schaap, F.G., Binas, B., Bonen, A., van der Vusse, G.J. and Luiken, J.J.F.P.
Acta Physiologica Scandinavica 178 (4): 367-371. August 2003

Continuous blood glucose monitoring reveals enormous circadian variations in pregnant diabetic rats.
Golic, M., Kräker, K., Fischer, C., Alenina, N., Haase, N., Herse, F., Schütte, T., Henrich, W., Müller, D.N., Busjahn, A., Bader, M. and Dechend, R.
Frontiers in Endocrinology 9 : 271. 29 May 2018

Diabetes mellitus in pregnancy leads to growth restriction and epigenetic modification of the Srebf2 gene in rat fetuses.
Golic, M., Stojanovska, V., Bendix, I., Wehner, A., Herse, F., Haase, N., Kräker, K., Fischer, C., Alenina, N., Bader, M., Schütte, T., Schuchardt, M., van der Giet, M., Henrich, W., Muller, D.N., Felderhoff-Müser, U., Scherjon, S., Plösch, T. and Dechend, R.
Hypertension 71 (5): 911-920. May 2018

Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3',5'-cyclic monophosphate-dependent pathway.
Gomes, E.R., Lara, A.A., Almeida, P.W., Guimaraes, D., Resende, R.R., Campagnole-Santos, M.J., Bader, M., Santos, R.A. and Guatimosim, S.
Hypertension 55 (1): 153-160. January 2010

Cardiovascular responses evoked by activation or blockade of GABA(A) receptors in the hypothalamic PVN are attenuated in transgenic rats with low brain angiotensinogen.
Gomes da Silva, A.Q., Xavier, C.H., Campagnole-Santos, M.J., Caligiorne, S.M., Baltatu, O.C., Bader, M., Santos, R.A. and Fontes, M.A.
Brain Research 1448 : 101-110. 11 April 2012

Dual effect of chemokine CCL7/MCP-3 in the development of renal tubulointerstitial fibrosis.
Gonzalez, J., Mouttalib, S., Delage, C., Calise, D., Maoret, J.J., Pradere, J.P., Klein, J., Buffin-Meyer, B., Van der Veen, B., Charo, I.F., Heeringa, P., Duchene, J., Bascands, J.L. and Schanstra, J.P.
Biochemical and Biophysical Research Communications 438 (2): 257-263. 23 August 2013

Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension.
Grabowski, K., Herlan, L., Witten, A., Qadri, F., Eisenreich, A., Lindner, D., Schädlich, M., Schulz, A., Subrova, J., Mhatre, K.N., Primessnig, U., Plehm, R., van Linthout, S., Escher, F., Bader, M., Stoll, M., Westermann, D., Heinzel, F.R. and Kreutz, R.
Hypertension Research 45 : 292-307. January 2022

Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease.
Gramlich, M., Michely, B., Krohne, C., Heuser, A., Erdmann, B., Klaassen, S., Hudson, B., Magarin, M., Kirchner, F., Todiras, M., Granzier, H., Labeit, S., Thierfelder, L. and Gerull, B.
Journal of Molecular and Cellular Cardiology 47 (3): 352-358. September 2009

Role of kinin B2 receptors in opioid-induced-hyperalgesia in inflammatory pain in mice.
Grastilleur, S., Mouledous, L., Bedel, J., Etcheverry, J., Bader, M., Girolami, J.P., Fourcade, O., Frances, B. and Minville, V.
Biological Chemistry 394 (3): 361-368. March 2013

Energy metabolism in human renin-gene transgenic rats. Does renin contribute to obesity?
Gratze, P., Boschmann, M., Dechend, R., Qadri, F., Malchow, J., Graeske, S., Engeli, S., Janke, J., Springer, J., Contrepas, A., Plehm, R., Klaus, S., Nguyen, G., Luft, F.C. and Mueller, D.N.
Hypertension 53 (3): 516-523. March 2009

Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
Gratze, P., Dechend, R., Stocker, C., Park, J.K., Feldt, S., Shagdarsuren, E., Wellner, M., Gueler, F., Rong, S., Gross, V., Obst, M., Plehm, R., Alenina, N., Zenclussen, A., Titze, J., Small, K., Yokota, Y., Zenke, M., Luft, F.C. and Mueller, D.N.
Circulation 117 (20): 2645-2656. 20 May 2008

Kinin B1 receptor modulates glucose homeostasis and physical exercise capacity by altering adrenal catecholamine synthesis and secretion.
Gregnani, M.F., Budu, A., Batista, R.O., Ornellas, F.H., Estrela, G.R., Arruda, A.C., Freitas-Lima, L.C., Kremer, J.L., Favaroni Mendes, L.A., Casarini, D.E., Lotfi, C.F.P., Oyama, L.M., Bader, M. and Araujo, R.C.
Molecular and Cellular Endocrinology 579 : 112085. 1 January 2024

Bradykinin B2 receptor signaling increases glucose uptake and oxidation: evidence and open questions.
Gregnani, M.F., Hungaro, T.G., Martins-Silva, L., Bader, M. and Araujo, R.C.
Frontiers in Pharmacology 11 : 1162. 4 August 2020

Alternative splicing and extensive RNA editing of human TPH2 transcripts.
Grohmann, M., Hammer, P., Walther, M., Paulmann, N., Buettner, A., Eisenmenger, W., Baghai, T.C., Schuele, C., Rupprecht, R., Bader, M., Bondy, B., Zill, P., Priller, J. and Walther, D.J.
PLoS ONE 5 (1): e8956. 29 January 2010

Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming.
Grohmann, M., Spada, F., Schermelleh, L., Alenina, N., Bader, M., Cardoso, M.C. and Leonhardt, H.
BMC Developmental Biology 5 : 18. 24 August 2005

Receptors, G proteins, and integration of calcium signalling.
Gudermann, T. and Bader, M.
Journal of Molecular Medicine 93 (9): 937-940. September 2015

Exercise induces renin-angiotensin system unbalance and high collagen expression in the heart of Mas-deficient mice.
Guimaraes, G.G., Santos, S.H.S., Oliveira, M.L., Pimenta-Veloso, E.P., Motta, D.F., Martins, A.S., Alenina, N., Bader, M., Santos, R.A.S. and Campagnole-Santos, M.J.
Peptides 38 (1): 54-61. November 2012

Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling.
Guimaraes, P.B., Alvarenga, E.C., Siqueira, P.D., Paredes-Gamero, E.J., Sabatini, R.A., Morais, R.L., Reis, R.I., Santos, E.L., Teixeira, L.G., Casarini, D.E., Martin, R.P., Shimuta, S.I., Carmona, A.K., Nakaie, C.R., Jasiulionis, M.G., Ferreira, A.T., Pesquero, J.L., Oliveira, S.M., Bader, M., Costa-Neto, C.M. and Pesquero, J.B.
Hypertension 57 (5): 965-972. May 2011

Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells.
Guimarães, P.B., da Silva, R.F., Hoff, C.C., Fernandes, L., Nakaie, C.R., Chagas, J.R., Karaoglanovic Carmona, A., Bader, M. and Pesquero, J.B.
Inflammation Research 68 (10): 845-855. October 2019

Relaxin does not improve angiotensin II-induced target-organ damage.
Haase, N., Rugor, J., Przybyl, L., Qadri, F., Müller, D.N. and Dechend, R.
PLoS ONE 9 (4): e93743. 7 April 2014

Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders.
Hadar, R., Edemann-Callesen, H., Reinel, C., Wieske, F., Voget, M., Popova, E., Sohr, R., Avchalumov, Y., Priller, J., van Riesen, C., Puls, I., Bader, M. and Winter, C.
Scientific Reports 6 : 39145. 15 December 2016

The effect of brain serotonin deficit (TPH2-KO) on the expression and activity of liver cytochrome P450 enzymes in aging male Dark Agouti rats.
Haduch, A., Bromek, E., Kuban, W., Basińska-Ziobroń, A., Danek, P.J., Alenina, N., Bader, M. and Daniel, W.A.
Pharmacological Reports 75 (6): 1522-1532. December 2023

Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats.
Haduch, A., Danek, P.J., Kuban, W., Pukło, R., Alenina, N., Gołębiowska, J., Popik, P., Bader, M. and Daniel, W.A.
Neurochemistry International 152 : 105223. January 2022

The effect of ageing and cerebral serotonin deficit on the activity of cytochrome P450 2D (CYP2D) in the brain and liver of male rats.
Haduch, A., Pukło, R., Alenina, N., Nikiforuk, A., Popik, P., Bader, M. and Daniel, W.A.
Neurochemistry International 141 : 104884. December 2020

Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M., Pablo-Tortola, C., Todiras, M., Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M., Jarosch, E., Sommer, T., Bröker, B.M., Felix, S.B., Scheidereit, C., Weber-Carstens, S., Butter, C., Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 11 (1): 103-119. February 2020

Beyond gene inactivation: evolution of tools for analysis of serotonergic circuitry.
Hainer, C., Mosienko, V., Koutsikou, S., Crook, J.J., Gloss, B., Kasparov, S., Lumb, B.M. and Alenina, N.
ACS Chemical Neuroscience 6 (7): 1116-1129. 15 July 2015

Role of the receptor Mas in macrophage-mediated inflammation in vivo.
Hammer, A., Yang, G., Friedrich, J., Kovacs, A., Lee, D.H., Grave, K., Jörg, S., Alenina, N., Grosch, J., Winkler, J., Gold, R., Bader, M., Manzel, A., Rump, L.C., Müller, D.N., Linker, R.A. and Stegbauer, J.
Proceedings of the National Academy of Sciences of the United States of America 113 (49): 14109-14114. 6 December 2016

Central control of fever and female body temperature by RANKL/RANK.
Hanada, R., Leibbrandt, A., Hanada, T., Kitaoka, S., Furuyashiki, T., Fujihara, H., Trichereau, J., Paolino, M., Qadri, F., Plehm, R., Klaere, S., Komnenovic, V., Mimata, H., Yoshimatsu, H., Takahashi, N., von Haeseler, A., Bader, M., Kilic, S.S., Ueta, Y., Pifl, C., Narumiya, S. and Penninger, J.M.
Nature 462 (7272): 505-509. 26 November 2009

Tail-cuff versus radiotelemetry to measure blood pressure in mice and rats.
Harrison, D.G., Bader, M., Lerman, L.O., Fink, G., Karumanchi, S.A., Reckelhoff, J.F., Sequeira-Lopez, M.L.S. and Touyz, R.M.
Hypertension 81 (1): 3-5. January 2024

Support for the involvement of TPH2 gene in affective disorders.
Harvey, M., Shink, E., Tremblay, M., Gagne, B., Raymond, C., Labbe, M., Walther, D.J., Bader, M. and Barden, N.
Molecular Psychiatry 9 (11): 980-981. 20 July 2004

Investigating the link between MCP-1 A-2518G, RANTES G-403A, CX3CR1 V249I and MTHFR C677T gene polymorphisms and the risk of acute myocardial infarction among Egyptians.
Hashad, I.M., Abdel Rahman, M.F., Alenina, N., Bader, M. and Gad, M.Z.
Meta Gene 11 : 181-188. February 2017

Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex.
Hermans-Borgmeyer, I., Hampe, W., Schinke, B., Methner, A., Nykjaer, A., Suesens, U., Fenger, U., Herbarth, B. and Schaller, H.C.
Mechanisms of Development 70 (1-2): 65-76. January 1998

B2 cells contribute to hypertension and natural killer cell activation possibly via AT1-AA in response to placental ischemia.
Herrock, O.T., Deer, E., Amaral, L.M., Campbell, N., Lemon, J., Ingram, N., Cornelius, D.C., Turner, T., Fitzgerald, S., Ibrahim, T., Dechend, R., Wallukat, G. and LaMarca, B.
American Journal of Physiology Renal Physiology 324 (2): F179-F192. February 2023

Arteriogenesis is modulated on bradykinin receptor signaling.
Hillmeister, P., Gatzke, N., Duelsner, A., Bader, M., Schadock, I., Hoefer, I., Hamann, I., Infante-Duarte, C., Jung, G., Troidl, K., Urban, D., Stawowy, P., Frentsch, M., Li, M., Nagorka, S., Wang, H., Shi, Y., le Noble, F. and Buschmann, I.
Circulation Research 109 (5): 524-533. 19 August 2011

Autonomic dysregulation in ob/ob mice is improved by inhibition of angiotensin-converting enzyme.
Hilzendeger, A.M., da Costa Goncalves, A.C., Plehm, R., Diedrich, A., Gross, V., Pesquero, J.B. and Bader, M.
Journal of Molecular Medicine 88 (4): 383-390. April 2010

Leptin regulates ACE activity in mice.
Hilzendeger, A.M., Morais, R.L., Todiras, M., Plehm, R., da Costa Goncalves, A., Qadri, F., Araujo, R.C., Gross, V., Nakaie, C.R., Casarini, D.E., Carmona, A.K., Bader, M. and Pesquero, J.B.
Journal of Molecular Medicine 88 (9): 899-907. September 2010

Controlling cardiomyocyte length: The role of renin and PPAR-γ.
Hinrichs, S., Heger, J., Schreckenberg, R., Wenzel, S., Euler, G., Arens, C., Bader, M., Rosenkranz, S., Caglayan, E. and Schlueter, K.D.
Cardiovascular Research 89 (2): 344-352. 1 February 2011

Agonistic autoantibodies against β2-adrenergic receptor influence retinal microcirculation in glaucoma suspects and patients.
Hohberger, B., Hosari, S., Wallukat, G., Kunze, R., Krebs, J., Müller, M., Hennig, T., Lämmer, R., Horn, F., Muñoz, L.E., Herrmann, M. and Mardin, C.
PLoS ONE 16 (5): e0249202. 7 May 2021

Agonistic β2-adrenergic receptor autoantibodies characterize the aqueous humor of patients with primary and secondary open-angle glaucoma.
Hohberger, B., Wörn, M., Lämmer, R., Mahajan, A., Mardin, C., Schötzer-Schrehardt, U., Kunze, R., Herrmann, M. and Wallukat, G.
Frontiers in Immunology 12 : 550236. 5 May 2021

The vesicular monoamine content regulates VMAT2 activity through G α(q) mouse platelets - evidence for autoregulation of vesicular transmitter update.
Holtje, M., Winter, S., Walther, D., Pahner, I., Hortnagl, H., Ottersen, O.P., Bader, M. and Ahnert-Hilger, G.
Journal of Biological Chemistry 278 (18): 15850-15858. 2 May 2003

The continued need for animals to advance brain research.
Homberg, J.R., Adan, R.A.H., Alenina, N., Asiminas, A., Bader, M., Beckers, T., Begg, D.P., Blokland, A., Burger, M.E., van Dijk, G., Eisel, U.L.M., Elgersma, Y., Englitz, B., Fernandez-Ruiz, A., Fitzsimons, C.P., van Dam, A.M., Gass, P., Grandjean, J., Havekes, R., Henckens, M.J.A.G., Herden, C., Hut, R.A., Jarrett, W., Jeffrey, K., Jezova, D., Kalsbeek, A., Kamermans, M., Kas, M.J., Kasri, N.N., Kiliaan, A.J., Kolk, S.M., Korosi, A., Korte, S.M., Kozicz, T., Kushner, S.A., Leech, K., Lesch, K.P., Lesscher, H., Lucassen, P.J., Luthi, A., Ma, L., Mallien, A.S., Meerlo, P., Mejias, J.F., Meye, F.J., Mitchell, A.S., Mul, J.D., Olcese, U., González, A.O., Olivier, J.D.A., Pasqualetti, M., Pennartz, C.M.A., Popik, P., Prickaerts, J., de la Prida, L.M., Ribeiro, S., Roozendaal, B., Rossato, J.I., Salari, A.A., Schoemaker, R.G., Smit, A.B., Vanderschuren, L.J.M.J., Takeuchi, T., van der Veen, R., Smidt, M.P., Vyazovskiy, V.V., Wiesmann, M., Wierenga, C.J., Williams, B., Willuhn, I., Wöhr, M., Wolvekamp, M., van der Zee, E.A. and Genzel, L.
Neuron 109 (15): 2374-2379. 4 August 2021

Comeback of the rat in biomedical research.
Homberg, J.R., Woehr, M. and Alenina, N.
ACS Chemical Neuroscience 8 (5): 900-903. 17 May 2017

Genetic deletion of the Angiotensin-(1-7) receptor Mas leads a reduced ovulatory rate.
Honorato-Sampaio, K., Ferreira Andrade, R., Bader, M., de Souza Martins, A., Souza Santos, R.A. and Reis, A.M.
Peptides 107 : 83-88. September 2018

Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying Acromesomelic Dysplasia type Maroteaux.
Hume, A.N., Buttgereit, J., Al-Awadhi, A.M., Al-Suwaidi, S.S., John, A., Bader, M., Seabra, M.C., Al-Gazali, L. and Ali, B.R.
Human Molecular Genetics 18 (2): 267-277. 15 January 2009

Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: Comparison to chronic phencyclidine and MK-801.
Hámor, P.U., Šírová, J., Páleníček, T., Zaniewska, M., Bubeníková-Valešová, V. and Schwendt, M.
Pharmacology Biochemistry and Behavior 175 : 89-100. December 2018

Cortisol dose-dependently impairs migration and tube-like formation in a trophoblast cell line and modulates inflammatory and angiogenic genes.
Húngaro, T.G.R, Gregnani, M.F., Alves-Silva, T., Herse, F., Alenina, N., Bader, M. and Araújo, R.C.
Biomedicines 9 (8): 980. August 2021

Identification of importin alpha 7 specific transport cargoes using a proteomic screening approach.
Hügel, S., Depping, R., Dittmar, G., Rother, F., Cabot, R., Sury, M.D., Hartmann, E. and Bader, M.
Molecular & Cellular Proteomics 13 (5): 1286-1298. 1 May 2014

Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger.
Ifuku, M., Faerber, K., Okuno, Y., Yamakawa, Y., Miyamoto, T., Nolte, C., Merrino, V.F., Kitada, S., Iwamoto, T., Komuro, I., Wang, B., Cheung, G., Ishikawa, E., Ooboshi, H., Bader, M., Wada, K., Kettenmann, H. and Noda, M.
Journal of Neuroscience 27 (48): 13065-13073. 28 November 2007

Androgen receptor independent cardiovascular action of the antiandrogen flutamide.
Iliescu, R., Campos, L.A., Schlegel, W.P., Morano, I., Baltatu, O. and Bader, M.
Journal of Molecular Medicine 81 (7): 420-427. July 2003

Genexpression und Morphologie der Follikel nach konventionellem Einfrieren und Vitrifikation von humanem Ovarialgewebe [Gene-expression and morphology of follicles after conventional freezing and vitrification of human ovarian tissue].
Isachenko, V., Isachenko, E., Nawroth, F., Wiegratz, I., Kaufmann, M., Lapidus, I., Hancke, K. and Kreienberg, R.
Geburtshilfe und Frauenheilkunde 70 (7): 561-567. July 2010

Human ovarian tissue vitrification versus conventional freezing: morphological, endocrinological, and molecular biological evaluation.
Isachenko, V., Lapidus, I., Isachenko, E., Krivokharchenko, A., Kreienberg, R., Woriedh, M., Bader, M. and Weiss, J.
Reproduction 138 (2): 319-327. August 2009

Angioprotectin: an angiotensin II-like peptide causing vasodilatory effects.
Jankowski, V., Toelle, M., Santos, R.A., Guenthner, T., Krause, E., Beyermann, M., Welker, P., Bader, M., Pinheiro, S.V.B., Sampaio, W.O., Lautner, R., Kretschmer, A., van der Giet, M., Zidek, W. and Jankowski, J.
FASEB Journal 25 (9): 2987-2995. September 2011

Mass-spectrometric identification of a novel angiotensin peptide in human plasma.
Jankowski, V., Vanholder, R., van der Giet, M., Toelle, M., Karadogan, S., Gobom, J., Furkert, J., Oksche, A., Krause, E., Tran, T.N., Tepel, M., Schuchardt, M., Schlueter, H., Wiedon, A., Beyermann, M., Bader, M., Todiras, M., Zidek, W. and Jankowski, J.
Arteriosclerosis Thrombosis and Vascular Biology 27 (2): 297-302. February 2007

Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice.
Jansch, M., Lubomirov, L.T., Trum, M., Williams, T., Schmitt, J., Schuh, K., Qadri, F., Maier, L.S., Bader, M. and Ritter, O.
FEBS Open Bio 13 (1): 118-132. January 2023

Adenosine (A)2A receptor modulation of nicotine-induced locomotor sensitization: a pharmacological and transgenic approach.
Jastrzebska, J., Nowak, E., Smaga, I., Bystrowska, B., Frankowska, M., Bader, M., Filip, M. and Fuxe, K.
Neuropharmacology 81 : 318-326. June 2014

Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction.
Järve, A., Mühlstedt, S., Qadri, F., Nickl, B., Schulz, H., Hübner, N., Özcelik, C. and Bader, M.
FASEB Journal 31 (2): 556-568. February 2017

Angiotensin-(1-7) receptor Mas deficiency does not exacerbate cardiac atrophy following high-level spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S., Alenina, N. and Bader, M.
Frontiers in Physiology 11 : 203. 12 March 2020

Angiotensin‐II receptor type Ia does not contribute to cardiac atrophy following high‐thoracic spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S. and Bader, M.
Experimental Physiology 105 (8): 1316-1325. 1 August 2020

Angiotensin-(1-7) receptor Mas in hemodynamic and thermoregulatory dysfunction after high-level spinal cord injury in mice: a pilot study.
Järve, A., Todiras, M., Kny, M., Fischer, F.I., Kraemer, J.F., Wessel, N., Plehm, R., Fielitz, J., Alenina, N. and Bader, M.
Frontiers in Physiology 9 : 1930. January 2019

Distinct roles of angiotensin receptors in autonomic dysreflexia following high-level spinal cord injury in mice.
Järve, A., Todiras, M., Lian, X, Filippelli-Silva, R., Qadri, F., Martin, R.P., Gollasch, M. and Bader, M.
Experimental Neurology 311 : 173-181. January 2019

Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin.
Kahn, R., Hellmark, T., Leeb-Lundberg, L.M., Akbari, N., Todiras, M., Olofsson, T., Wieslander, J., Christensson, A., Westman, K., Bader, M., Mueller-Esterl, W. and Karpman, D.
Journal of Immunology 182 (12): 7906-7915. 15 June 2009

The bradykinin B2 receptor in the early immune response against Listeria infection.
Kaman, W.E., Wolterink, A.F., Bader, M., Boele, L.C. and van der Kleij, D.
Medical Microbiology and Immunology 198 (1): 39-46. February 2009

Serotonin limits generation of chromaffin cells during adrenal organ development.
Kameneva, P., Melnikova, V.I., Kastriti, M.E., Kurtova, A., Kryukov, E., Murtazina, A., Faure, L., Poverennaya, I., Artemov, A.V., Kalinina, T.S., Kudryashov, N.V., Bader, M., Skoda, J., Chlapek, P., Curylova, L., Sourada, L., Neradil, J., Tesarova, M., Pasqualetti, M., Gaspar, P., Yakushov, V.D., Sheftel, B.I., Zikmund, T., Kaiser, J., Fried, K., Alenina, N., Voronezhskaya, E.E. and Adameyko, I.
Nature Communications 13 (1): 2901. 25 May 2022