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Sleeping Beauty hits them all: transposon-mediated saturation mutagenesis in the mouse germline

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Item Type:Editorial
Title:Sleeping Beauty hits them all: transposon-mediated saturation mutagenesis in the mouse germline
Creators: Izsvak, Z. ORCID logoORCID: https://orcid.org/0000-0002-2053-2384 and Ivics, Z. ORCID logoORCID: https://orcid.org/0000-0002-7803-6658
Abstract:The Sleeping Beauty (SB) transposon emerged as a useful tool for applications such as germline and somatic cell insertional mutagenesis and now shows its usefulness again by facilitating saturating germline mutagenesis in mice.
Keywords:DNA Transposable Elements, Genetic Vectors, Germ-Line Mutation, Insertional Mutagenesis, Animals, Mice
Source:Nature Methods
ISSN:1548-7091
Publisher:Nature Publishing Group
Volume:2
Number:10
Page Range:735-736
Date:October 2005
Official Publication:https://doi.org/10.1038/nmeth1005-735
PubMed:View item in PubMed

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