![[feed]](/style/images/feed-icon-14x14.png){kind=icon}
Tools
Tools
| Item Type: | Article |
|---|---|
| Title: | Identical lesion morphology in primary progressive and relapsing-remitting MS -an ultrahigh field MRI study |
| Creators: |
Kuchling, J.  ORCID: https://orcid.org/0000-0002-7981-2073, Ramien, C., Bozin, I., Dörr, J., Harms, L., Rosche, B., Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Sinnecker, T. and Wuerfel, J. ORCID: https://orcid.org/0000-0002-0034-8053
|
| Abstract: | Potential differences between primary progressive (PP) and relapsing-remitting (RR) multiple sclerosis (MS) have been controversially discussed. In this study, we compared lesion morphology and distribution in patients with PPMS and RRMS (nine in each group) using 7 T MRI. We found that gray and white matter lesions in PPMS and RRMS patients did not differ in their respective morphological characteristics (e.g. perivascular p = 0.863, hypointense rim p = 0.796, cortical lesion count p = 0.436). Although limited by a small sample size, our study results suggest that PPMS and RRMS, despite differences in disease course and clinical characteristics, exhibit identical lesion morphology under ultrahigh field MRI. |
| Keywords: | MRI, Primary Progressive Multiple Sclerosis, PPMS, Relapsing-Remitting Multiple Sclerosis, RRMS, Ultrahigh Field MRI, 7 T MRI |
| Source: | Multiple Sclerosis Journal |
| ISSN: | 1352-4585 |
| Publisher: | Sage Publications |
| Volume: | 20 |
| Number: | 14 |
| Page Range: | 1866-1871 |
| Date: | December 2014 |
| Official Publication: | https://doi.org/10.1177/1352458514531084 |
| PubMed: | View item in PubMed |
Repository Staff Only: item control page
