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Experimental validation of a preclinical SPECT/MR insert

Item Type:Article
Title:Experimental validation of a preclinical SPECT/MR insert
Creators Name:Carminati, M., Occhipinti, M., Baratelli, F. M., Montagnani, G. L., Nagy, K., Nyitrai, Z., Nagy, A., Czeller, M., Kühne, A., Niendorf, T., Mathe, D., Belloli, S., Valtorta, S., Moresco, R. M., Falini, A., Iadanza, A., Ottobrini, L. and Fiorini, C.
Abstract:The experimental characterization of a SiPM-based 10-module SPECT gamma imager suitable for insertion and operation inside unmodified MR scanners for simultaneous (and potentially multi-tracer) preclinical imaging is presented. The design challenges, here fulfilled, such as compactness while granting proper cooling, mutual compatibility and resilience to high (3-7 T) magnetic fields inside the bore, suitable energetic (better than 14% at 140 keV) and spatial resolution (better than 1 mm) are discussed. The carefully optimized detection module, featuring a 5 × 5 cm 2 CsI(Tl) scintillator coupled to arrays of SiPM conditioned by a 36-channel ASIC, and the digital daisy chain infrastructure are the basis for the realization of a larger (20-module ring) clinical insert. Moreover, planar image reconstruction based on advanced statistical approaches such as maximum likelihood and iteratively estimated light response function is reported.
Source:IEEE Nuclear Science Symposium and Medical Imaging Conference
Title of Book:2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
Page Range:18264750
Official Publication:https://doi.org/10.1109/NSSMIC.2017.8532678

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