Article
Pan-cancer analysis of whole genomes.
Nature 578
(7793): 82-93.
6 February 2020
Computational pan-genomics: status, promises and challenges.
Briefings in Bioinformatics 19
(1): 118-135.
January 2018
Phylogenetic ctDNA analysis depicts early stage lung cancer evolution.
Abbosh, C., Birkbak, N.J., Wilson, G.A., Jamal-Hanjani, M., Constantin, T., Salari, R., Quesne, J.L., Moore, D.A., Veeriah, S., Rosenthal, R., Marafioti, T., Kirkizlar, E., Watkins, T.B.K., McGranahan, N., Ward, S., Martinson, L., Riley, J., Fraioli, F., Bakir, M.A., Grönroos, E., Zambrana, F., Endozo, R., Bi, W.L., Fennessy, F.M., Sponer, N., Johnson, D., Laycock, J., Shafi, S., Czyzewska-Khan, J., Rowan, A., Chambers, T., Matthews, N., Turajlic, S., Hiley, C., Lee, S.M., Forster, M.D., Ahmad, T., Falzon, M., Borg, E., Lawrence, D., Hayward, M., Kolvekar, S., Panagiotopoulos, N., Janes, S.M., Thakrar, R., Ahmed, A., Blackhall, F., Summers, Y., Hafez, D., Naik, A., Ganguly, A., Kareht, S., Shah, R., Joseph, L., Quinn, A.M., Crosbie, P., Naidu, B., Middleton, G., Langman, G., Trotter, S., Nicolson, M., Remmen, H., Kerr, K., Chetty, M., Gomersall, L., Fennell, D.A., Nakas, A., Rathinam, S., Anand, G., Khan, S., Russell, P., Ezhil, V., Ismail, B., Irvin-Sellers, M., Prakash, V., Lester, J.F., Kornaszewska, M., Attanoos, R., Adams, H., Davies, H., Oukrif, D., Akarca, A.U., Hartley, J.A., Lowe, H.L., Lock, S., Iles, N., Bell, H., Ngai, Y., Elgar, G., Szallasi, Z., Schwarz, R.F., Herrero, J., Stewart, A., Quezada, S.A., Van Loo, P., Dive, C., Lin, C.J., Rabinowitz, M., Aerts, H.J.W.L., Hackshaw, A., Shaw, J.A., Zimmermann, B.G. and Swanton, C.
Nature 545
(7655): 446-451.
25 May 2017
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Abbosh, C., Frankell, A.M., Harrison, T., Kisistok, J., Garnett, A., Johnson, L., Veeriah, S., Moreau, M., Chesh, A., Chaunzwa, T.L., Weiss, J., Schroeder, M.R., Ward, S., Grigoriadis, K., Shahpurwalla, A., Litchfield, K., Puttick, C., Biswas, D., Karasaki, T., Black, J.R.M., Martínez-Ruiz, C., Bakir, M.A.l., Pich, O., Watkins, T.B.K., Lim, E.L., Huebner, A., Moore, D.A., Godin-Heymann, N., L'Hernault, A., Bye, H., Odell, A., Roberts, P., Gomes, F., Patel, A.J., Manzano, E., Hiley, C.T., Carey, N., Riley, J., Cook, D.E., Hodgson, D., Stetson, D., Barrett, J.C., Kortlever, R.M., Evan, G.I., Hackshaw, A., Daber, R.D., Shaw, J.A., Aerts, H.J.W.L., Licon, A., Stahl, J., Jamal-Hanjani, M., Birkbak, N.J., McGranahan, N. and Swanton, C.
Nature 616
(7957): 553-562.
20 April 2023
Impaired human hematopoiesis due to a cryptic intronic splicing mutation.
Abdulhay, N.J., Fiorini, C., Verboon, J.M., Ludwig, L.S., Ulirsch, J.C., Zieger, B., Lareau, C.A., Mi, X., Roy, A., Obeng, E.A., Erlacher, M., Gupta, N., Gabriel, S.B., Ebert, B.L., Niemeyer, C.M., Khoriaty, R.N., Ancliff, P., Gazda, H.T., Wlodarski, M.W. and Sankaran, V.G.
Journal of Experimental Medicine 216
(5): 1050-1060.
6 May 2019
Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice.
Abolhassani, M., Guais, A., Sanders, E., Campion, F., Fichtner, I., Bonte, J., Baronzio, G., Fiorentini, G., Israel, M. and Schwartz, L.
Investigational New Drugs 30
(4): 1331-1342.
August 2012
Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes.
Abruzzi, K.C., Lacadie, S. and Rosbash, M.
EMBO Journal 23
(13): 2620-2631.
7 July 2004
Comparative evaluation of the biological properties of reducible and acid-sensitive folate prodrugs of a highly potent doxorubicin derivative.
Abu Ajaj, K., El-Abadla, N., Welker, P., Azab, S., Zeisig, R., Fichtner, I. and Kratz, F.
European Journal of Cancer 48
(13): 2054-2065.
September 2012
In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B.
Abu Ajaj, K., Graeser, R., Fichtner, I. and Kratz, F.
Cancer Chemotherapy and Pharmacology 64
(2): 413-418.
July 2009
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous, E.T., Stolzenberg, S., Sticht, J., Wieczorek, M., Roske, Y., Günther, M., Dähn, S., Boesen, B.B., Calvo, M.M., Biese, C., Kuppler, F., Medina-García, Á., Álvaro-Benito, M., Höfer, T., Noé, F. and Freund, C.
Nature Chemical Biology 19
(10): 1196-1204.
October 2023
Malaria-specific antibody responses and parasite persistence after infection of mice with Plasmodium chabaudi chabaudi.
Achtman, A.H., Stephens, R., Cadman, E.T., Harrison, V. and Langhorne, J.
Parasite Immunology 29
(9): 435-444.
September 2007
CCR7-deficient mice develop atypically persistent germinal centers in response to thymus-independent type 2 antigens.
Achtman, A.H., Höpken, U.E., Bernert, C. and Lipp, M.
Journal of Leukocyte Biology 85
(3): 409-417.
March 2009
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.
Ackermann, T., Hartleben, G., Müller, C., Mastrobuoni, G., Groth, M., Sterken, B.A., Zaini, M.A., Youssef, S.A., Zuidhof, H.R., Krauss, S.R., Kortman, G., de Haan, G., de Bruin, A., Wang, Z.Q., Platzer, M., Kempa, S. and Calkhoven, C.F.
Communications Biology 2
: 208.
14 June 2019
Genetic determinants of micronucleus formation in vivo.
Adams, D.J., Barlas, B., McIntyre, R.E., Salguero, I., van der Weyden, L., Barros, A., Vicente, J.R., Karimpour, N., Haider, A., Ranzani, M., Turner, G., Thompson, N.A., Harle, V., Olvera-León, R., Robles-Espinoza, C.D., Speak, A.O., Geisler, N., Weninger, W.J., Geyer, S.H., Hewinson, J., Karp, N.A., Fu, B., Yang, F., Kozik, Z., Choudhary, J., Yu, L., van Ruiten, M.S., Rowland, B.D., Lelliott, C.J., Del Castillo Velasco-Herrera, M., Verstraten, R., Bruckner, L., Henssen, A.G., Rooimans, M.A., de Lange, J., Mohun, T.J., Arends, M.J., Kentistou, K.A., Coelho, P.A., Zhao, Y., Zecchini, H., Perry, J.R.B., Jackson, S.P. and Balmus, G.
Nature 627
(8002): 130-136.
7 March 2024
Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel.
Adema, A.D., Laan, A.C., Myhren, F., Fichtner, I., Verheul, H.M., Sandvold, M.L. and Peters, G.J.
International Journal of Oncology 36
(1): 285-294.
1 January 2010
[S3-Guidelines "Exocrine pancreatic cancer" 2007.] S3-Leitlinie "Exokrines Pankreaskarzinom" 2007.
Adler, G., Seufferlein, T., Bischoff, S.C., Brambs, H.J., Feuerbach, S., Grabenbauer, G., Hahn, S., Heinemann, V., Hohenberger, W., Langrehr, J.M., Lutz, M.P., Neuhaus, H., Neuhaus, P., Oettle, H., Schlag, P.M., Schmid, R., Schmiegel, W., Schlottmann, K., Werner, J., Wiedenmann, B. and Kopp, I.
Zeitschrift fuer Gastroenterologie 45
: 487-523.
June 2007
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8(+) T cell responses.
Agerer, B., Koblischke, M., Gudipati, V., Montaño-Gutierrez, L.F., Smyth, M., Popa, A., Genger, J.W., Endler, L., Florian, D.M., Mühlgrabner, V., Graninger, M., Aberle, S.W., Husa, A.M., Shaw, L.E., Lercher, A., Gattinger, P., Torralba-Gombau, R., Trapin, D., Penz, T., Barreca, D., Fae, I., Wenda, S., Traugott, M., Walder, G., Pickl, W.F., Thiel, V., Allerberger, F., Stockinger, H., Puchhammer-Stöckl, E., Weninger, W., Fischer, G., Hoepler, W., Pawelka, E., Zoufaly, A., Valenta, R., Bock, C., Paster, W., Geyeregger, R., Farlik, M., Halbritter, F., Huppa, J.B., Aberle, J.H. and Bergthaler, A.
Science Immunology 6
(57): eabg6461.
March 2021
T cell homing to tumors detected by 3D-coordinated positron emission tomography and magnetic resonance imaging.
Agger, R., Petersen, M.S., Petersen, C.C., Hansen, S.B., Stodkilde-Jorgensen, H., Skands, U., Blankenstein, T., Andersen, T.E., Hulgaard, E.F., Jorgensen, J.T., Marqversen, J., Gundersen, H.J. and Hokland, M.E.
Journal of Immunotherapy 30
(1): 29-39.
January 2007
A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4(+) T cells and is defective in Crohn's disease patients.
Ahlers, J., Mantei, A., Lozza, L., Stäber, M., Heinrich, F., Bacher, P., Hohnstein, T., Menzel, L., Yüz, S.G., Alvarez-Simon, D., Bickenbach, A.R., Weidinger, C., Mockel-Tenbrinck, N., Kühl, A.A., Siegmund, B., Maul, J., Neumann, C. and Scheffold, A.
Mucosal Immunology 15
(3): 480-490.
May 2022
Nicotine strongly activates dendritic cell-mediated adaptive immunity - Potential role for progression of atherosclerotic lesions.
Aicher, A., Heeschen, C., Mohaupt, M., Cooke, J.P., Zeiher, A.M. and Dimmeler, S.
Circulation 107
(4): 604-611.
4 February 2003
1H, 15N and 13C assignments of the cysteine protease inhibitor Chagasin from Trypanosoma cruzi.
Aido-Machado, R., Salmon, D., Diehl, A., Leidert, M., Schmetzer, O., de Lima, A.P.C.A., Scharfstein, J., Oschkinat, H. and Pires, J.R.
Journal of Biomolecular NMR 36 (Suppl)
(1): 30.
December 2006
Gab1 and Mapk signaling are essential in the hair cycle and hair follicle stem cell quiescence.
Akilli Öztürk, Ö., Pakula, H., Chmielowiec, J., Qi, J., Stein, S., Lan, L., Sasaki, Y., Rajewsky, K. and Birchmeier, W.
Cell Reports 13
(3): 561-572.
20 October 2015
The evolution of non-small cell lung cancer metastases in TRACERx.
Al Bakir, M., Huebner, A., Martínez-Ruiz, C., Grigoriadis, K., Watkins, T.B.K., Pich, O., Moore, D.A., Veeriah, S., Ward, S., Laycock, J., Johnson, D., Rowan, A., Razaq, M., Akther, M., Naceur-Lombardelli, C., Prymas, P., Toncheva, A., Hessey, S., Dietzen, M., Colliver, E., Frankell, A.M., Bunkum, A., Lim, E.L., Karasaki, T., Abbosh, C., Hiley, C.T., Hill, M.S., Cook, D.E., Wilson, G.A., Salgado, R., Nye, E., Stone, R.K., Fennell, D.A., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Summers, Y., Lindsay, C.R., Blackhall, F.H., Cave, J., Blyth, K.G., Nair, A., Ahmed, A., Taylor, M.N., Procter, A.J., Falzon, M., Lawrence, D., Navani, N., Thakrar, R.M., Janes, S.M., Papadatos-Pastos, D., Forster, M.D., Lee, S.M., Ahmad, T., Quezada, S.A., Peggs, K.S., Van Loo, P., Dive, C., Hackshaw, A., Birkbak, N.J., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
(7957): 534-542.
April 2023
Body composition and lung cancer-associated cachexia in TRACERx.
Al-Sawaf, O., Weiss, J., Skrzypski, M., Lam, J.M., Karasaki, T., Zambrana, F., Kidd, A.C., Frankell, A.M., Watkins, T.B.K., Martínez-Ruiz, C., Puttick, C., Black, J.R.M., Huebner, A., Bakir, M.A., Sokač, M., Collins, S., Veeriah, S., Magno, N., Naceur-Lombardelli, C., Prymas, P., Toncheva, A., Ward, S., Jayanth, N., Salgado, R., Bridge, C.P., Christiani, D.C., Mak, R.H., Bay, C., Rosenthal, M., Sattar, N., Welsh, P., Liu, Y., Perrimon, N., Popuri, K., Beg, M.F., McGranahan, N., Hackshaw, A., Breen, D.M., O'Rahilly, S., Birkbak, N.J., Aerts, H.J.W.L., Jamal-Hanjani, M. and Swanton, C.
Nature Medicine 29
(4): 846-858.
April 2023
Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A., Xavier, A., Abu Lubad, M., Sigulla, J., Kessler, M., Hurwitz, R. and Meyer, T.F.
EBioMedicine 23
: 100-110.
September 2017
The metabolic background is a global player in Saccharomyces gene expression epistasis.
Alam, M.T., Zelezniak, A., Mülleder, M., Shliaha, P., Schwarz, R., Capuano, F., Vowinckel, J., Radmaneshfar, E., Krüger, A., Calvani, E., Michel, S., Börno, S., Christen, S., Patil, K.R., Timmermann, B., Lilley, K.S. and Ralser, M.
Nature Microbiology 1
: 15030.
1 February 2016
From operating table to laboratory bench: the path toward metastasis research from the clinical setting.
Alberto Vilchez, M. and Rau, B.
Methods in Molecular Biology 2294
: 325-333.
2021
Distinct functional properties of the TAP subunits coordinate the nucleotide-dependent transport cycle.
Alberts, P., Daumke, O., Deverson, E.V., Howard, J.C. and Knittler, M.R.
Current Biology 11
(4): 242-51.
20 February 2001
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H., Flórez, A.F., Kreth, S., Brückner, L.M., Yildiz, U., Gartlgruber, M., Odoni, D.I., Poschet, G., Garbowicz, K., Shao, C., Klein, C., Meier, J., Zeisberger, P., Nadler-Holly, M., Ziehm, M., Paul, F., Burhenne, J., Bell, E., Shaikhkarami, M., Würth, R., Stainczyk, S.A., Wecht, E.M., Kreth, J., Büttner, M., Ishaque, N., Schlesner, M., Nicke, B., Stresemann, C., Llamazares-Prada, M., Reiling, J.H., Fischer, M., Amit, I., Selbach, M., Herrmann, C., Wölfl, S., Henrich, K.O., Höfer, T., Trumpp, A. and Westermann, F.
Nature Cancer 3
(4): 471-485.
28 April 2022
Spontaneous non-sustained ventricular tachycardia and premature ventricular contractions and their prognostic relevance in patients with cancer in routine care.
Albrecht, A., Porthun, J., Eucker, J., Coats, A.J.S., von Haehling, S., Pezzutto, A., Karakas, M., Riess, H., Keller, U., Landmesser, U., Haverkamp, W., Anker, S.D. and Anker, M.S.
Cancers 13
(10): 2303.
12 May 2021
Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Alcaniz, J., Winkler, L., Dahlmann, M., Becker, M., Orthmann, A., Haybaeck, J., Krassnig, S., Skofler, C., Kratzsch, T., Kuhn, S.A., Jödicke, A., Linnebacher, M., Fichtner, I., Walther, W. and Hoffmann, J.
Frontiers in Oncology 13
: 1129627.
11 April 2023
Characterization of protein-binding to the spinach chloroplast psbA mRNA 5' untranslated region.
Alexander, C., Faber, N. and Klaff, P.
Nucleic Acids Research 26
(10): 2265-2272.
15 May 1998
Tumor-derived extracellular vesicles impair CD171-specific CD4(+) CAR T cell efficacy.
Ali, S., Toews, K., Schwiebert, S., Klaus, A., Winkler, A., Grunewald, L., Oevermann, L., Deubzer, H.E., Tüns, A., Jensen, M.C., Henssen, A.G., Eggert, A., Schulte, J.H., Schwich, E., Rebmann, V., Schramm, A. and Künkele, A.
Frontiers in Immunology 11
: 531.
31 March 2020
Cell fixation and preservation for droplet-based single-cell transcriptomics.
Alles, J., Karaiskos, N., Praktiknjo, S.D., Grosswendt, S., Wahle, P., Ruffault, P.L., Ayoub, S., Schreyer, L., Boltengagen, A., Birchmeier, C., Zinzen, R., Kocks, C. and Rajewsky, N.
BMC Biology 15
(1): 44.
19 May 2017
Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L., Peeva, P., Ramos-Prats, A., Alenina, N., Winter, Y. and Rivalan, M.
Behavioural Brain Research 377
: 112188.
13 January 2020
Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology.
Amthauer, H., Denecke, T., Rau, B., Hildebrandt, B., Huenerbein, M., Ruf, J., Schneider, U., Gutberlet, M., Schlag, P.M., Felix, R. and Wust, P.
European Journal of Nuclear Medicine and Molecular Imaging 31
(6): 811-819.
1 January 2004
In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C., Acemel, R.D., Jedamzick, J., Bolondi, A., Cova, G., Brieske, N., Kühn, R., Wittler, L., Real, F.M. and Lupiáñez, D.G.
Nature Genetics 54
(7): 1026-1036.
July 2022
Molecular pathways: comparing the effects of drugs and T cells to effectively target oncogenes.
Anders, K. and Blankenstein, T.
Clinical Cancer Research 19
(2): 320-326.
15 January 2013
Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.
Anders, K., Buschow, C., Charo, J. and Blankenstein, T.
Transgenic Research 21
(5): 1099-1107.
October 2012
Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K., Buschow, C., Herrmann, A., Milojkovic, A., Loddenkemper, C., Kammertoens, T., Daniel, P., Yu, H., Charo, J. and Blankenstein, T.
Cancer Cell 20
(6): 755-767.
13 December 2011
Microarray meta-analysis defines global angiogenesis-related gene expression signatures in human carcinomas.
Anders, M., Fehlker, M., Wang, Q., Wissmann, C., Pilarsky, C., Kemmner, W. and Hoecker, M.
Molecular Carcinogenesis 52
(1): 29-38.
January 2013
Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression.
Anders, M., Vieth, M., Roecken, C., Ebert, M., Pross, M., Gretschel, S., Schlag, P.M., Wiedenmann, B., Kemmner, W. and Hoecker, M.
British Journal of Cancer 100
(2): 352-359.
27 January 2009
The immune system prevents recurrence of transplanted but not autochthonous antigenic tumors after oncogene inactivation therapy.
Anders, K., Kershaw, O., Larue, L., Gruber, A.D. and Blankenstein, T.
International Journal of Cancer 141
(12): 2551-2561.
15 December 2017
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing.
Andersch, L., Radke, J., Klaus, A., Schwiebert, S., Winkler, A., Schumann, E., Grunewald, L., Zirngibl, F., Flemmig, C., Jensen, M.C., Rossig, C., Joussen, A., Henssen, A., Eggert, A., Schulte, J.H. and Künkele, A.
BMC Cancer 19
(1): 895.
9 September 2019
Phosphorylation-dependent down-regulation of c-Myb DNA binding is abrogated by a point mutation in the v-myb oncogene.
Andersson, K.B., Kowenz-Leutz, E., Brendeford, E.M., Tygsett, A.H.H., Leutz, A. and Gabrielsen, O.S.
Journal of Biological Chemistry 278
(6): 3816-3824.
7 February 2003
Mining the literature: new methods to exploit keyword profiles.
Andrade-Navarro, M.A.
Genome Medicine 4
(10): 81.
30 October 2012
A method for cell type marker discovery by high-throughput gene expression analysis of mixed cell populations.
Andrade-Navarro, M.A., Kanji, F., Palii, C.G., Brand, M., Atkins, H. and Perez-Iratxeta, C.
BMC Biotechnology 13
(1): 80.
3 October 2013
De novo whole genome assembly of the Roborovski dwarf hamster (Phodopus roborovskii) genome, an animal model for severe/critical COVID-19.
Andreotti, S., Altmüller, J., Quedenau, C., Borodina, T., Nouailles, G., Teixeira Alves, L.G., Landthaler, M., Bieniara, M., Trimpert, J. and Wyler, E.
Genome Biology and Evolution 14
(7): evac100.
July 2022
An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.
Andres, D., Gohlke, U., Broeker, N.K., Schulze, S., Rabsch, W., Heinemann, U., Barbirz, S. and Seckler, R.
Glycobiology 23
(4): 486-494.
April 2013
Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system.
Andresen, D., Roske, Y., Doering, C., Heinemann, U., Seckler, R. and Barbirz, S.
Molecular Microbiology 83
(6): 1244-1253.
March 2012
CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition.
Andreu-Saumell, I., Rodriguez-Garcia, A., Mühlgrabner, V., Gimenez-Alejandre, M., Marzal, B., Castellsagué, J., Brasó-Maristany, F., Calderon, H., Angelats, L., Colell, S., Nuding, M., Soria-Castellano, M., Barbao, P., Prat, A., Urbano-Ispizua, A., Huppa, J.B. and Guedan, S.
Nature Communications 15
(1): 3552.
26 April 2024
destiny: diffusion maps for large-scale single-cell data in R.
Angerer, P., Haghverdi, L., Büttner, M., Theis, F.J., Marr, C. and Buettner, F.
Bioinformatics 32
(8): 1241-1243.
15 April 2016
Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming.
Anh, L.P.H., Nishimura, K., Kuno, A., Nguyen, T.L., Kato, T., Ohtaka, M., Nakanishi, M., Sugihara, E., Sato, T.A., Hayashi, Y., Fukuda, A. and Hisatake, K.
Stem Cells 40
(4): 397-410.
29 April 2022
New cardiovascular biomarkers in patients with advanced cancer – a prospective study comparing MR-proADM, MR-proANP, copeptin, high-sensitivity troponin T and NT-proBNP.
Anker, M.S., Lück, L.C., Khan, M.S., Porthun, J., Hadzibegovic, S., Lena, A., Wilkenshoff, U., Weinländer, P., Evertz, R., Totzeck, M., Mahabadi, A.A., Rassaf, T., Anker, S.D., Bullinger, L., Keller, U., Karakas, M., Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure
26 November 2024
(In Press)
Patient-reported ability to walk 4 m and to wash: New clinical endpoints and predictors of survival in patients with pre-terminal cancer.
Anker, M.S., Lena, A., Roeland, E.J., Porthun, J., Schmitz, S., Hadzibegovic, S., Sikorski, P., Wilkenshoff, U., Fröhlich, A.K., Ramer, L.V., Rose, M., Eucker, J., Rassaf, T., Totzeck, M., Lehmann, L.H., von Haehling, S., Coats, A.J.S., Friede, T., Butler, J., Anker, S.D., Riess, H., Landmesser, U., Bullinger, L., Keller, U. and Ahn, J.
Journal of Cachexia Sarcopenia and Muscle 14
(4): 1670-1681.
August 2023
Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire.
Anker, M.S., Potthoff, S.K., Lena, A., Porthun, J., Hadzibegovic, S., Evertz, R., Denecke, C., Fröhlich, A.K., Sonntag, F., Regitz-Zagrosek, V., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Spertus, J.A., Anker, S.D., Karakas, M., Bullinger, L., Keller, U., Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 25
(9): 1635-1647.
September 2023
B-Myb, a repressed trans-activating protein.
Ansieau, S., Kowenz-Leutz, E., Dechend, R. and Leutz, A.
Journal of Molecular Medicine 75
(11-12): 815-819.
November 1997
Early life stress regulates cardiac development through an IL4-glucocorticoid signaling balance.
Apaydin, D.C., Jaramillo, P.A.M., Corradi, L., Cosco, F., Rathjen, F.G., Kammertoens, T., Filosa, A. and Sawamiphak, S.
Cell Reports 33
(7): 108404.
17 November 2020
Functionalized bead assay to measure three-dimensional traction forces during T-cell activation.
Aramesh, M., Mergenthal, S., Issler, M., Plochberger, B., Weber, F., Qin, X.H., Liska, R., Duda, G.N., Huppa, J.B., Ries, J., Schütz, G.J. and Klotzsch, E.
Nano Letters 21
(1): 507-514.
13 January 2021
CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations.
Arce, S., Luger, E., Muehlinghaus, G., Cassese, G., Hauser, A., Horst, A., Lehnert, K., Odendahl, M., Hoenemann, D., Heller, K.D., Kleinschmidt, H., Berek, C., Doerner, T., Krenn, V., Hiepe, F., Bargou, R., Radbruch, A. and Manz, R.A.
Journal of Leukocyte Biology 75
: 1022-1028.
1 January 2004
Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M., Dimitriou, S., Stahler, A., Hablesreiter, R., Strzelecka, P.M., Stein, C.M., Tilgner, M., Saiki, R., Ogawa, S., Bullinger, L., Modest, D.P., Stintzing, S., Heinemann, V. and Damm, F.
Blood 139
(10): 1593-1597.
10 March 2022
Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.
Arends, C.M., Galan-Sousa, J., Hoyer, K., Chan, W., Jäger, M., Yoshida, K., Seemann, R., Noerenberg, D., Waldhueter, N., Fleischer-Notter, H., Christen, F., Schmitt, C.A., Dörken, B., Pelzer, U., Sinn, M., Zemojtel, T., Ogawa, S., Märdian, S., Schreiber, A., Kunitz, A., Krüger, U., Bullinger, L., Mylonas, E., Frick, M. and Damm, F.
Leukemia 32
(9): 1908-1919.
September 2018
Dynamics of clonal hematopoiesis under DNA-damaging treatment in patients with ovarian cancer.
Arends, C.M., Kopp, K., Hablesreiter, R., Estrada, N., Christen, F., Moll, U.M., Zeillinger, R., Schmitt, W.D., Sehouli, J., Kulbe, H., Fleischmann, M., Ray-Coquard, I., Zeimet, A., Raspagliesi, F., Zamagni, C., Vergote, I., Lorusso, D., Concin, N., Bullinger, L., Braicu, E.I. and Damm, F.
Leukemia 38
(6): 1378-1389.
June 2024
Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M., Liman, T.G., Strzelecka, P.M., Kufner, A., Löwe, P., Huo, S., Stein, C.M., Piper, S.K., Tilgner, M., Sperber, P.S., Dimitriou, S., Heuschmann, P., Hablesreiter, R., Harms, C., Bullinger, L., Weber, J.E., Endres, M. and Damm, F.
Blood 141
(7): 787-799.
16 February 2023
Eukaryotic expression: developments for structural proteomics.
Aricescu, A.R., Assenberg, R., Bill, R.M., Busso, D., Chang, V.T., Davis, S.J., Dubrovsky, A., Gustafsson, L., Hedfalk, K., Heinemann, U., Jones, I.M., Ksiazek, D., Lang, C., Maskos, K., Messerschmidt, A., Macieira, S., Peleg, Y., Perrakis, A., Poterszman, A., Schneider, G., Sixma, T.K., Sussman, J.L., Sutton, G., Tarboureich, N., Zeev-Ben-Mordehai, T. and Jones, E.Y.
Acta Crystallographica Section D 62
(Pt. 10): 1114-1124.
October 2006
Colon cancer metastasis: MACC1 and Met as metastatic pacemakers.
Arlt, F. and Stein, U.
International Journal of Biochemistry and Cell Biology 41
(12): 2356-2359.
December 2009
Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect.
Arlt, B., Mastrobuoni, G., Wuenschel, J., Astrahantseff, K., Eggert, A., Kempa, S. and Deubzer, H.E.
Journal of Enzyme Inhibition and Medicinal Chemistry 36
(1): 1282-1289.
30 June 2021
Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt, B., Zasada, C., Baum, K., Wuenschel, J., Mastrobuoni, G., Lodrini, M., Astrahantseff, K., Winkler, A., Schulte, J.H., Finkler, S., Forbes, M., Hundsdoerfer, P., Guergen, D., Hoffmann, J., Wolf, J., Eggert, A., Kempa, S. and Deubzer, H.E.
International Journal of Cancer 148
(5): 1219-1232.
1 March 2021
SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K., Kranz, A., Fohgrub, J., Jolly, A., Bledau, A.S., Di Virgilio, M., Lesche, M., Dahl, A., Höfer, T., Stewart, A.F. and Waskow, C.
Blood 131
(12): 1311-1324.
22 March 2018
Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.
Arnhold, V., Schmelz, K., Proba, J., Winkler, A., Wünschel, J., Toedling, J., Deubzer, H.E., Künkele, A., Eggert, A., Schulte, J.H. and Hundsdoerfer, P.
Oncotarget 9
(2): 2304-2319.
2018
The germinal center response is impaired in the absence of T cell-expressed CXCR5.
Arnold, C.N., Campbell, D.J., Lipp, M. and Butcher, E.C.
European Journal of Immunology 37
(1): 100-109.
January 2007
Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Horst, D., Rau, B., Stein, U. and Treese, C.
Pathology Research and Practice 215
(11): 152662.
November 2019
Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. and Treese, C.
Clinical and Translational Oncology 22
(12): 2357-2363.
December 2020
Immunohistochemical analysis of nicotinamide phosphoribosyltransferase expression in gastric and esophageal adenocarcinoma (AEG).
Arnold, A., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Krenzien, F., Stein, U. and Treese, C.
Gastrointestinal Disorders 4
(4): 333-340.
13 December 2022
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A., Roske, Y., Barth, C., Lleras Forero, L., Bravo-Rodriguez, K., Redel, Al., Kostova, S., McShane, E., Opitz, R., Faelber, K., Rau, K., Mielke, T., Daumke, O., Selbach, M., Sanchez-Garcia, E., Rocks, O., Panáková, D., Heinemann, U. and Wanker, E.E.
Nature Communications 7
: 13047.
20 October 2016
An alignment-free method to identify candidate orthologous enhancers in multiple Drosophila genomes.
Arunachalam, M., Jayasurya, K., Tomancak, P. and Ohler, U.
Bioinformatics 26
(17): 2109-2115.
1 September 2010
Prospective tracking of donor-reactive T-cell clones in the circulation and rejecting human kidney allografts.
Aschauer, C., Jelencsics, K., Hu, K., Heinzel, A., Gregorich, M.G., Vetter, J., Schaller, S., Winkler, S.M., Weinberger, J., Pimenov, L., Gualdoni, G.A., Eder, M., Kainz, A., Troescher, A.R., Regele, H., Reindl-Schwaighofer, R., Wekerle, T., Huppa, J.B., Sykes, M. and Oberbauer, R.
Frontiers in Immunology 12
: 750005.
14 October 2021
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C., Mouktaroudi, M., Krämer, B., Oestreich, M., Antonakos, N., Nuesch-Germano, M., Gkizeli, K., Bonaguro, L., Reusch, N., Baßler, K., Saridaki, M., Knoll, R., Pecht, T., Kapellos, T.S., Doulou, S., Kröger, C., Herbert, M., Holsten, L., Horne, A., Gemünd, I.D., Rovina, N., Agrawal, S., Dahm, K., van Uelft, M., Drews, A., Lenkeit, L., Bruse, N., Gerretsen, J., Gierlich, J., Becker, M., Händler, K., Kraut, M., Theis, H., Mengiste, S., Domenico, E., Schulte-Schrepping, J., Seep, L., Raabe, J., Hoffmeister, C., ToVinh, M., Keitel, V., Rieke, G., Talevi, V., Skowasch, D., Aziz, N.A., Pickkers, P., van de Veerdonk, F.L., Netea, M.G., Schultze, J.L., Kox, M., Breteler, M.M.B., Nattermann, J., Koutsoukou, A., Giamarellos-Bourboulis, E.J. and Ulas, T.
Genome Medicine 13
(1): 7.
13 January 2021
Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles.
Aschman, T., Wyler, E., Baum, O., Hentschel, A., Rust, R., Legler, F., Preusse, C., Meyer-Arndt, L., Büttnerova, I., Förster, A., Cengiz, D., Teixeira Alves, L.G., Schneider, J., Kedor, C., Bellmann-Strobl, J., Sanchin, A., Goebel, H.H., Landthaler, M., Corman, V., Roos, A., Heppner, F.L., Radbruch, H., Paul, F., Scheibenbogen, C., Dengler, N.F. and Stenzel, W.
Acta Neuropathologica Communications 11
(1): 193.
8 December 2023
Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.
Ash, M.R., Faelber, K., Kosslick, D., Albert, G.I., Roske, Y., Kofler, M., Schuemann, M., Krause, E. and Freund, C.
Structure 18
(8): 944-954.
11 August 2010
Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk.
Ashktorab, H., Hermann, P., Nouraie, M., Shokrani, B., Lee, E., Haidary, T., Brim, H. and Stein, U.
Journal of Translational Medicine 14
(1): 215.
20 July 2016
Saffron: The golden spice with therapeutic properties on digestive diseases.
Ashktorab, H., Soleimani, A., Singh, G., Amr, A., Tabtabaei, S., Latella, G., Stein, U., Akhondzadeh, S., Solanki, N., Gondré-Lewis, M.C., Habtezion, A. and Brim, H.
Nutrients 11
(5): 943.
26 April 2019
Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.
Aslam, M.A., Alemdehy, M.F., Kwesi-Maliepaard, E.M., Muhaimin, F.I., Caganova, M., Pardieck, I.N., van den Brand, T., van Welsem, T., de Rink, I., Song, J.Y., de Wit, E., Arens, R., Jacobs, H. and van Leeuwen, F.
EMBO Reports 22
(2): e51184.
3 February 2021
CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia.
Astori, A., Fredly, H., Aloysius, T.A., Bullinger, L., Mansat-De Mas, V., de la Grange, P., Delhommeau, F., Hagen, K.M., Récher, C., Dusanter-Fourt, I., Knappskog, S., Lillehaug, J.R., Pendino, F. and Bruserud, Ø.
Oncotarget 4
(9): 1438-1448.
September 2013
REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis.
Astrosini, C., Roeefzaad, C., Dai, Y.Y., Dieckgraefe, B.K., Joens, T. and Kemmner, W.
International Journal of Cancer 123
(2): 409-413.
15 July 2008
Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.
Augustin, I., Gross, J., Baumann, D., Korn, C., Kerr, G., Grigoryan, T., Mauch, C., Birchmeier, W. and Boutros, M.
Journal of Experimental Medicine 210
(9): 1761-1777.
26 August 2013
IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors.
Authier, H., Billot, K., Derudder, E., Bordereaux, D., Riviere, P., Rodrigues-Ferreira, S., Nahmias, C. and Baud, V.
Proceedings of the National Academy of Sciences of the United States of America 111
(41): 14794-14799.
14 October 2014
The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches.
Avancena, P., Song, T., Yao, Y., Fehlner-Peach, H., Diamond, B., Gu, H., Rajewsky, K. and Zou, Y.R.
Proceedings of the National Academy of Sciences of the United States of America 118
(30): e2100576118.
27 July 2021
Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol.
Avvakumov, G.V., Grishkovskaya, I., Muller, Y.A. and Hammond, G.L.
Journal of Biological Chemistry 277
(47): 45219-45225.
22 November 2002
Determination of interaction kinetics between the T cell receptor and peptide-loaded MHC class II via single-molecule diffusion measurements.
Axmann, M., Huppa, J.B., Davis, M.M. and Schütz, G.J.
Biophysical Journal 103
(2): L17-9.
18 July 2012
Single molecule fluorescence microscopy on planar supported bilayers.
Axmann, M., Schütz, G.J. and Huppa, J.B.
Journal of Visualized Experiments
(105): e53158.
31 October 2015
Measuring TCR-pMHC binding in situ using a FRET-based microscopy assay.
Axmann, M., Schütz, G.J. and Huppa, J.B.
Journal of Visualized Experiments
(105): e53157.
30 October 2015
Structure and function of the Bacillus hybrid enzyme GluXyn-1: Native-like jellyroll fold preserved after insertion of autonomous globular domain.
Ay, J., Goetz, F., Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 95
(12): 6613-6618.
9 June 1998
Steady state migratory RelB(+) Langerin(+) dermal dendritic cells mediate peripheral induction of antigen-specific CD4(+) CD25(+) Foxp3(+) regulatory T cells.
Azukizawa, H., Doehler, A., Kanazawa, N., Nayak, A., Lipp, M., Malissen, B., Autenrieth, I., Katayama, I., Riemann, M., Weih, F., Berberich-Siebelt, F. and Lutz, M.B.
European Journal of Immunology 41
(5): 1420-1434.
May 2011
A rapid embryonic stem cell-based mouse model for B-cell lymphomas driven by Epstein-Barr virus protein LMP1.
Ba, Z., Meng, F.L., Gostissa, M., Huang, P.Y., Ke, Q., Wang, Z., Dao, M.N., Fujiwara, Y., Rajewsky, K., Zhang, B. and Alt, F.W.
Cancer Immunology Research 3
(6): 641-649.
June 2015
Loss of m(1)acp(3)Ψ ribosomal RNA modification is a major feature of cancer.
Babaian, A., Rothe, K., Girodat, D., Minia, I., Djondovic, S., Milek, M., Spencer Miko, S.E., Wieden, H.J., Landthaler, M., Morin, G.B. and Mager, D.L.
Cell Reports 31
(5): 107611.
5 May 2020
Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome.
Babaylova, E., Graifer, D., Malygin, A., Stahl, J., Shatsky, I. and Karpova, G.
Nucleic Acids Research 37
(4): 1141-1151.
March 2009
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.
Baccin, C., Al-Sabah, J., Velten, L., Helbling, P.M., Grünschläger, F., Hernández-Malmierca, P., Nombela-Arrieta, C., Steinmetz, L.M., Trumpp, A. and Haas, S.
Nature Cell Biology 22
(1): 38-48.
January 2020
Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells.
Bachmeier, B., Fichtner, I., Killian, P.H., Kronski, E., Pfeffer, U. and Efferth, T.
PLoS ONE 6
(5): e20550.
26 May 2011
STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis.
Backert, I., Koralov, S.B., Wirtz, S., Kitowski, V., Billmeier, U., Martini, E., Hofmann, K., Hildner, K., Wittkopf, N., Brecht, K., Waldner, M., Rajewsky, K., Neurath, M.F., Becker, C. and Neufert, C.
Journal of Immunology 193
(7): 3779-3791.
1 October 2014
RNA-bioinformatics: tools, services and databases for the analysis of RNA-based regulation.
Backofen, R., Engelhardt, J., Erxleben, A., Fallmann, J., Grüning, B., Ohler, U., Rajewsky, N. and Stadler, P.F.
Journal of Biotechnology 261
: 76-84.
10 November 2017
Suppression of peripheral pain by blockade of voltage-gated calcium 2.2 channels in nociceptors induces RANKL and impairs recovery from inflammatory arthritis in a mouse model.
Baddack, U., Frahm, S., Antolin-Fontes, B., Grobe, J., Lipp, M., Mueller, G. and Ibanez-Tallon, I.
Arthritis & Rheumatology 67
(6): 1657-1667.
June 2015
A chronic model of arthritis supported by a strain-specific periarticular lymph node in BALB/c mice.
Baddack, U., Hartmann, S., Bang, H., Grobe, J., Loddenkemper, C., Lipp, M. and Mueller, G.
Nature Communications 4
: 1644.
2013
Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis.
Baddack-Werncke, U., Busch-Dienstfertig, M., Gonzalez-Rodriguez, S., Maddila, S.C., Grobe, J., Lipp, M., Stein, C. and Mueller, G.
Journal of Neuroinflammation 14
(1): 30.
6 February 2017
Apoptosis-induced cleavage of keratin 15 and keratin 17 in a human breast epithelial cell line.
Badock, V., Steinhusen, U., Bommert, K., Wittmann-Liebold, B. and Otto, A.
Cell Death and Differentiation 8
(3): 308-315.
1 March 2001
Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K., von Delbrück, M., Dittmar, G., Scheffner, M., Ziv, I., Glickman, M.H., Ciechanover, A. and Sommer, T.
Molecular Cell 50
(4): 528-539.
23 May 2013
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey, M.H., Meyerson, W.U., Dursi, L.J., Wang, L.B., Dong, G., Liang, W.W., Weerasinghe, A., Li, S., Li, Y., Kelso, S., Saksena, G., Ellrott, K., Wendl, M.C., Wheeler, D.A., Getz, G., Simpson, J.T., Gerstein, M.B. and Ding, Li
Nature Communications 11
(1): 4748.
21 September 2020
Essential role of c-myc in ara-C-induced differentiation of human erythroleukemia cells.
Baker, S.J., Pawlita, M., Leutz, A. and Hoelzer, D.
Leukemia 8
(8): 1309-1317.
August 1994
In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia.
Bakina, O., Conrad, T., Mitic, N., Vidal, R.O., Obrusnik, T., Sai, S., Nolte, C., Semtner, M. and Kettenmann, H.
PLoS ONE 19
(7): e0302376.
11 July 2024
Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S., Andreani, M., Goncalves Andrade, J., Saha, T., Sundaravinayagam, D., Garzón, J., Zhang, W., Popp, O., Hiraga, S., Rahjouei, A., Rosen, D.B., Mertins, P., Chait, B.T., Donaldson, A.D. and Di Virgilio, M.
eLife 11
: e75047.
13 April 2022
Binding of Drosophila ORC proteins to anaphase chromosomes requires cessation of mitotic cyclin-dependent kinase activity.
Baldinger, T. and Gossen, M.
Molecular and Cellular Biology 29
(1): 140-149.
January 2009
Immune phenotypes and checkpoint molecule expression of clonally expanded lymph node-infiltrating T cells in classical Hodgkin lymphoma.
Ballhausen, A., Ben Hamza, A., Welters, C., Dietze, K., Bullinger, L., Rahn, H.P., Hartmann, S., Hansmann, M.L. and Hansmann, L.
Cancer Immunology Immunotherapy 72
(2): 515-521.
February 2023
Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR.
Balyschew, N., Yushkevich, A., Mikirtumov, V., Sanchez, R.M., Sprink, T. and Kudryashev, M.
Nature Communications 14
(1): 6543.
17 October 2023
Role of β-catenin in synaptic vesicle localization and presynaptic assembly.
Bamji, S.X., Shimazu, K., Kimes, N., Huelsken, J., Birchmeier, W., Lu, B. and Reichardt, L.F.
Neuron 40
(4): 719-731.
November 2003
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembling cofactors ASPL/PUX1.
Banchenko, S., Arumughan, A., Petrović, S., Schwefel, D., Wanker, E.E., Roske, Y. and Heinemann, U.
Structure 27
(12): 1830-1841.
3 December 2019
First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.
Banci, L., Bertini, I., Cusack, S., de Jong, R.N., Heinemann, U., Jones, E.Y., Kozielski, F., Maskos, K., Messerschmidt, A., Owens, R., Perrakis, A., Poterszman, A., Schneider, G., Siebold, C., Silman, I., Sixma, T., Stewart-Jones, G., Sussman, J.L., Thierry, J.C. and Moras, D.
Acta Crystallographica Section D 62
(Pt. 10): 1208-1217.
October 2006
Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases.
Bandapalli, O.R., Geheeb, M., Kobelt, D., Kuehnle, K., Elezkurtaj, S., Herrmann, J., Gressner, A.M., Weiskirchen, R., Beule, D., Blüthgen, N., Herzel, H., Franke, C. and Brand, K.
International Journal of Cancer 118
: 74-89.
1 January 2006
Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo.
Bannon, J.H., Fichtner, I., O'Neill, A., Pampillon, C., Sweeney, N.J., Strohfeldt, K., Watson, R.W., Tacke, M. and McGee, M.M.
British Journal of Cancer 97
(9): 1234-1241.
5 November 2007
In contrast to Western diet, a plant-based, high-fat, low-sugar diet does not exacerbate retinal endothelial injury in streptozotocin-induced diabetes.
Barakat, A., Nakao, S., Zandi, S., Sun, D., Schmidt-Ullrich, R., Hayes, K.C. and Hafezi-Moghadam, A.
FASEB Journal 33
(9): 10327-10338.
September 2019
Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D., Hörtenhuber, M., Balwierz, P.J., Zehnder, T., Mukarram, A.K., Nepal, C., Várnai, C., Hadzhiev, Y., Jimenez-Gonzalez, A., Li, N., Wragg, J., D'Orazio, F.M., Relic, D., Pachkov, M., Díaz, N., Hernández-Rodríguez, B., Chen, Z., Stoiber, M., Dong, M., Stevens, I., Ross, S.E., Eagle, A., Martin, R., Obasaju, O., Rastegar, S., McGarvey, A.C., Kopp, W., Chambers, E., Wang, D., Kim, H.R., Acemel, R.D., Naranjo, S., Łapiński, M., Chong, V., Mathavan, S., Peers, B., Sauka-Spengler, T., Vingron, M., Carninci, P., Ohler, U., Lacadie, S.A., Burgess, S.M., Winata, C., van Eeden, F., Vaquerizas, J.M., Gómez-Skarmeta, J.L., Onichtchouk, D., Brown, B.J., Bogdanovic, O., van Nimwegen, E., Westerfield, M., Wardle, F.C, Daub, C.O., Lenhard, B. and Müller, F.
Nature Genetics 54
(7): 1037-1050.
July 2022
Dynamics of the ligand binding domain layer during AMPA receptor activation.
Baranovic, J., Chebli, M., Salazar, H., Carbone, A.L., Faelber, K., Lau, A.Y., Daumke, O. and Plested, A.J.R.
Biophysical Journal 110
(4): 896-911.
23 February 2016
Subsequent malignancies among long-term survivors of Hodgkin lymphoma and non-Hodgkin lymphoma: a pooled analysis of German cancer registry data (1990-2012).
Baras, N., Dahm, S., Haberland, J., Janz, M., Emrich, K., Kraywinkel, K. and Salama, A.
British Journal of Haematology 177
(2): 226-242.
April 2017
Crystal structure of Escherichia coli phage HK620 tailspike: podoviral tailspike endoglycosidase modules are evolutionarily related.
Barbirz, S., Mueller, J.J., Uetrecht, C., Clark, A.J., Heinemann, U. and Seckler, R.
Molecular Microbiology 69
(2): 303-316.
July 2008
PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries.
Barbosa-Silva, A., Fontaine, J.F., Donnard, E.R., Stussi, F., Ortega, J.M. and Andrade-Navarro, M.A.
BMC Bioinformatics 12
(1): 435.
9 November 2011
Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.
Barettino, D., Bugge, T.H., Bartunek, P., Vivanco Ruiz, M.D., Sonntag-Buck, V., Beug, H., Zenke, M. and Stunnenberg, H.G.
EMBO Journal 12
(4): 1343-1354.
April 1993
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
Bargou, R.C., Emmerich, F., Krappmann, D., Bommert, K., Mapara, M.Y., Arnold, W., Royer, H.D., Grinstein, E., Greiner, A., Scheidereit, C. and Doerken, B.
Journal of Clinical Investigation 100
(12): 2961-2969.
15 December 1997
Characterization of a novel Hodgkin cell-line, HD-MyZ, HD-Myr, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.
Bargou, R.C., Mapara, M.Y., Zugck, C., Daniel, P.T., Pawlita, M., Doehner, H. and Doerken, B.
Journal of Experimental Medicine 177
(5): 1257-1268.
1 May 1993
Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, R.C., Wagener, C., Bommert, K., Arnold, W., Daniel, P.T., Mapara, M.Y., Grinstein, E., Royer, H.D. and Doerken, B.
Journal of Experimental Medicine 183
(3): 1205-1213.
1 March 1996
Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.
Bargou, R.C., Wagener, C., Bommert, K., Mapara, M.Y., Daniel, P.T., Arnold, W., Dietel, M., Guski, H., Feller, A., Royer, H.D. and Doerken, B.
Journal of Clinical Investigation 97
(11): 2651-2659.
1 June 1996
Experimental observation of a fundamental length scale of waves in random media.
Barkhofen, S., Metzger, J.J., Fleischmann, R., Kuhl, U. and Stöckmann, H.J.
Physical Review Letters 111
(18): 183902.
1 November 2013
Co-regulation of two gene activities by tetracycline via a bidirectional promoter.
Baron, U., Freundlieb, S., Gossen, M. and Bujard, H.
Nucleic Acids Research 23
(17): 3605-3606.
11 September 1995
Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential.
Baron, U., Gossen, M. and Bujard, H.
Nucleic Acids Research 25
(14): 2723-2729.
15 July 1997
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Barone, M., Müller, M., Chiha, S., Ren, J., Albat, D., Soicke, A., Dohmen, S., Klein, M., Bruns, J., van Dinther, M., Opitz, R., Lindemann, P., Beerbaum, M., Motzny, K., Roske, Y., Schmieder, P., Volkmer, R., Nazaré, M., Heinemann, U., Oschkinat, H., Ten Dijke, P., Schmalz, H.G. and Kühne, R.
Proceedings of the National Academy of Sciences of the United States of America 117
(47): 29684-29690.
24 November 2020
OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation.
Barrera, M., Koob, S., Dikov, D., Vogel, F. and Reichert, A.S.
FEBS Letters 590
(19): 3309-3322.
October 2016
Cyclin D3: requirement for G1/S transition and high abundance in quiescent tissues suggest a dual role in proliferation and differentiation.
Bartkova, J., Lukas, J., Strauss, M. and Bartek, J.
Oncogene 17
(8): 1027-1037.
27 August 1998
Active promoters and insulators are marked by the centrosomal protein 190.
Bartkuhn, M., Straub, T., Herold, M., Herrmann, M., Rathke, C., Saumweber, H., Gilfillan, G.D., Becker, P.B. and Renkawitz, R.
EMBO Journal 28
(7): 877-888.
8 April 2009
Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H., Balogh, A., Yakoub, M., Homann, S., Markó, L., Höges, S., Tsvetkov, D., Krannich, A., Wundersitz, S., Avery, E.G., Haase, N., Kräker, K., Hering, L., Maase, M., Kusche-Vihrog, K., Grandoch, M., Fielitz, J., Kempa, S., Gollasch, M., Zhumadilov, Z., Kozhakhmetov, S., Kushugulova, A., Eckardt, K.U., Dechend, R., Rump, L.C., Forslund, S.K., Müller, D.N., Stegbauer, J. and Wilck, N.
Circulation 139
(11): 1407-1421.
12 March 2019
The Myb leucine zipper is essential for leukemogenicity of the v-Myb protein.
Bartunek, P., Karafiat, V., Dvorakova, M., Zahorova, V., Mandikova, S., Zenke, M. and Dvorak, M.
Oncogene 15
(24): 2939-2949.
11 December 1997
GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter.
Bartunek, P., Kralova, J., Blendinger, G., Dvorak, M. and Zenke, M.
Oncogene 22
(13): 1927-1935.
3 April 2003
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
Basheer, F., Giotopoulos, G., Meduri, E., Yun, H., Mazan, M., Sasca, D., Gallipoli, P., Marando, L., Gozdecka, M., Asby, R., Sheppard, O., Dudek, M., Bullinger, L., Döhner, H., Dillon, R., Freeman, S., Ottmann, O., Burnett, A., Russell, N., Papaemmanuil, E., Hills, R., Campbell, P., Vassiliou, G.S.. and Huntly, B.J.P.
Journal of Experimental Medicine 216
(4): 966-981.
1 April 2019
Enhancement of CRISPR-Cas9 induced precise gene editing by targeting Histone H2A-K15 ubiquitination.
Bashir, S., Dang, T., Rossius, J., Wolf, J. and Kuehn, R.
BMC Biotechnology 20
(1): 57.
23 October 2020
CD40 activity on mesenchymal cells negatively regulates OX40L to maintain bone marrow immune homeostasis under stress conditions.
Bassani, B., Tripodo, C., Portararo, P., Gulino, A., Botti, L., Chiodoni, C., Jachetti, E., Bolli, N., Ciciarello, M., Joehrens, K., Anagnostopoulos, I., Na, I.K., Curti, A., Colombo, M.P. and Sangaletti, S.
Frontiers in Immunology 12
: 662048.
18 May 2021
Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A., Malhan, D., Dumbani, M., Dahlmann, M., Stein, U. and Relógio, A.
Cancers 14
(14): 3458.
16 July 2022
Synergistic activity of bortezomib and HDACis in preclinical models of B-cell precursor acute lymphoblastic leukemia via modulation of p53, PI3K/AKT and NF-κB.
Bastian, L., Hof, J., Pfau, M., Fichtner, I., Eckert, C., Henze, G., Prada, J., von Stackelberg, A., Seeger, K. and Shalapour, S.
Clinical Cancer Research 19
(6): 1445-1457.
15 March 2013
Unblending of transcriptional condensates in human repeat expansion disease.
Basu, S., Mackowiak, S.D., Niskanen, H., Knezevic, D., Asimi, V., Grosswendt, S., Geertsema, H., Ali, S., Jerković, I., Ewers, H., Mundlos, S., Meissner, A., Ibrahim, D.M. and Hnisz, D.
Cell 181
(5): 1062-1079.
28 May 2020
Extraembryonic gut endoderm cells undergo programmed cell death during development.
Batki, J., Hetzel, S., Schifferl, D., Bolondi, A., Walther, M., Wittler, L., Grosswendt, S., Herrmann, B.G. and Meissner, A.
Nature Cell Biology 26
(6): 868-877.
June 2024
Transcriptional repression and activation in the same cell type of the human c-MYC promoter by the retinoblastoma gene protein: antagonisation of both effects by SV40 T antigen.
Batsche, E., Lipp, M. and Cremisi, C.
Oncogene 9
(8): 2235-2243.
August 1994
Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis.
Bauer, M.K.A., Schubert, A., Rocks, O. and Grimm, S.
Journal of Cell Biology 147
(7): 1493-1502.
27 December 1999
Feedback, mass conservation and reaction kinetics impact the robustness of cellular oscillations.
Baum, K., Politi, A.Z., Kofahl, B., Steuer, R. and Wolf, J.
PLoS Computational Biology 12
(12): e1005298.
27 December 2016
Analysis of correlation-based biomolecular networks from different omics data by fitting stochastic block models.
Baum, K., Rajapakse, J.C. and Azuaje, F.
F1000Research 8
: 465.
27 August 2019
Of gene expression and cell division time: a mathematical framework for advanced differential gene expression and data analysis.
Baum, K., Schuchhardt, J., Wolf, J. and Busse, D.
Cell Systems 9
(6): 569-579.
18 December 2019
State-of-the-art analytical methods of viral infections in human lung organoids.
Baumgardt, M., Hülsemann, M., Löwa, A., Fatykhova, D., Hoffmann, K., Kessler, M., Mieth, M., Hellwig, K., Frey, D., Langenhagen, A., Voss, A., Obermayer, B., Wyler, E., Dökel, S., Gruber, A.D., Tölch, U., Hippenstiel, S., Hocke, A.C. and Hönzke, K.
PLoS ONE 17
(12): e0276115.
20 December 2022
Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022.
Baumgartner, F., Baer, C., Bamopoulos, S.A., Ayoub, E., Truger, M., Meggendorfer, M., Lenk, M., Hoermann, G., Hutter, S., Müller, H., Walter, W., Mueller, M.L., Nadarajah, Ni., Blombery, P., Keller, U., Kern, W., Haferlach, C. and Haferlach, T.
Blood 143
(12): 1139-1156.
21 March 2024
Activation of gp130 signaling in T cells drives T(H)17-mediated multi-organ autoimmunity.
Baumgartner, F., Bamopoulos, S.A., Faletti, L., Hsiao, H.J., Holz, M., Gonzalez-Menendez, I., Solé-Boldo, L., Horne, A., Gosavi, S., Özerdem, C., Singh, N., Liebig, S., Ramamoorthy, S., Lehmann, M., Demel, U., Kühl, A.A., Wartewig, T., Ruland, J., Wunderlich, F.T., Schick, M., Walther, W., Rose-John, S., Haas, S., Quintanilla-Martinez, L., Feske, S., Ehl, S., Glauben, R. and Keller, U.
Science Signaling 17
(824): eadc9662.
20 February 2024
Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A., Zelarayan, L., Betney, R., Gehrke, C., Dunger, S., Noack, C., Busjahn, A., Huelsken, J., Taketo, M.M., Birchmeier, W., Dietz, R. and Bergmann, M.W.
Circulation Research 100
(9): 1353-1362.
11 May 2007
Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics.
Bayram, S., Razzaque, Y.S., Geisberger, S., Pietzke, M., Fürst, S., Vechiatto, C., Forbes, M., Mastrobuoni, G. and Kempa, S.
Frontiers in Molecular Biosciences 9
: 859787.
12 August 2022
Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M., Terkelsen, T., Bartels, A.S., Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G.I., Fang, X., Mann, M. and Moreira, J.M.A.
Gastroenterology 165
(1): 121-132.e5.
July 2023
PRC1-mediated gene silencing in pluripotent ES cells: function and evolution.
Becker, M., Mah, N., Zdzieblo, D., Li, X., Mer, A.S., Andrade-Navarro, M.A. and Mueller, A.M.
Epigenetics and Human Health 2015
: 141-166.
18 November 2014
Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM.
Becker, M., Sommer, A., Kraetzschmar, J.R., Seidel, H., Pohlenz, H.D. and Fichtner, I.
Molecular Cancer Therapeutics 4
: 151-170.
1 January 2005
Direct homo- and hetero-interactions of MeCP2 and MBD2.
Becker, A., Allmann, L., Hofstätter, M., Casa, V., Weber, P., Lehmkuhl, A., Herce, H.D. and Cardoso, M.C.
PLoS ONE 8
(1): e53730.
15 January 2013
Poly(ADP-ribosyl)ation of Methyl CpG binding domain protein 2 regulates chromatin structure.
Becker, A., Zhang, P., Allmann, L., Meilinger, D., Bertulat, B., Eck, D., Hofstaetter, M., Bartolomei, G., Hottiger, M.O., Schreiber, V., Leonhardt, H. and Cardoso, M.C.
Journal of Biological Chemistry 291
(10): 4873-4881.
4 March 2016
Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia.
Becker, H., Pfeifer, D., Ihorst, G., Pantic, M., Wehrle, J., Rüter, B.H., Bullinger, L., Hackanson, B., Germing, U., Kuendgen, A., Platzbecker, U., Döhner, K., Ganser, A., Hagemeijer, A., Wijermans, P.W., Döhner, H., Duyster, J. and Lübbert, M.
Annals of Hematology 99
(7): 1551-1560.
July 2020
The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration.
Becker, M.S., Müller, P.M., Bajorat, J., Schroeder, A., Giaisi, M., Amin, E., Ahmadian, M.R., Rocks, O., Köhler, R., Krammer, P.H. and Li-Weber, M.
Oncotarget 7
(32): 51908-51921.
9 August 2016
The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression.
Becker, M.S., Schmezer, P., Breuer, R., Haas, S.F., Essers, M.A., Krammer, P.H. and Li-Weber, M.
Cell Death & Disease 5
: e1000.
January 2014
A model of the mammalian circadian oscillator including the REV-ERBalpha module.
Becker-Weimann, S., Wolf, J., Kramer, A. and Herzel, H.
Genome Informatics 15
(1): 3-12.
2004
Cancer evolution: mathematical models and computational inference.
Beerenwinkel, N., Schwarz, R.F., Gerstung, M. and Markowetz, F.
Systematic Biology 64
(1): e1-e25.
January 2015
Oligomeric structure of mammalian purine nucleoside phosphorylase in solution determined by analytical ultracentrifugation.
Behlke, J., Koellner, G. and Bzowska, A.
Zeitschrift fuer Naturforschung C, A Journal of Biosciences 60
(11-12): 927-931.
November 2005
Protein crystallization with and without precipitants.
Behlke, J., Marg, A. and Paeschke, M.
Journal of Applied Crystallography 30
(5/1): 559-560.
1 October 1997
Enhanced resolution of sedimentation coefficient distribution profiles by extrapolation to infinite time.
Behlke, J. and Ristau, O.
European Biophysics Journal 39
(3): 449-455.
February 2010
Molecular mass determination by sedimentation velocity experiments and direct fitting of the concentration profiles.
Behlke, J. and Ristau, O.
Biophysical Journal 72
(1): 428-434.
January 1997
Self-association of adrenodoxin studied by using analytical ultracentrifugation.
Behlke, J., Ristau, O., Mueller, E.C., Hannemann, F. and Bernhardt, R.
Biophysical Chemistry 125
(1): 159-165.
January 2007
Loss of tumourigenicity of stably ERbeta-transfected MCF-7 breast cancer cells.
Behrens, D., Gill, J.H. and Fichtner, I.
Molecular and Cellular Endocrinology 274
(1-2): 19-29.
15 August 2007
The mTOR pathway inhibitor RAD001 (everolimus) is highly efficacious in tamoxifen-sensitive and -resistant breast cancer xenografts.
Behrens, D., Lykkesfeldt, A.E. and Fichtner, I.
Targeted Oncology 2
(3): 135-144.
July 2007
Control of beta-catenin signaling in tumor development.
Behrens, J.
Annals of the New York Academy of Sciences 910
: 21-35.
June 2000
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Behrens, J., Jerchow, B.A., Wuertele, M., Grimm, J., Asbrand, C., Wirtz, R., Kuehl, M., Wedlich, D. and Birchmeier, W.
Science 280
(5363): 596-599.
24 April 1998
Functional interaction of beta-catenin with the transcription factor LEF-1.
Behrens, J., von Kries, J.P., Kuehl, M., Bruhn, L., Wedlich, D., Grosschedl, R. and Birchmeier, W.
Nature 382
(6592): 638-642.
15 August 1996
Establishment and thorough characterization of xenograft (PDX) models derived from patients with pancreatic cancer for molecular analyses and chemosensitivity testing.
Behrens, D., Pfohl, U., Conrad, T., Becker, M., Brzezicha, B., Büttner, B., Wagner, S., Hallas, C., Lawlor, R., Khazak, V., Linnebacher, M., Wartmann, T., Fichtner, I., Hoffmann, J., Dahlmann, M. and Walther, W.
Cancers 15
(24): 5753.
8 December 2023
Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K., Goergen, H., Hitz, F., Zijlstra, J.M., Greil, R., Markova, J., Sasse, S., Fuchs, M., Topp, M.S., Soekler, M., Mathas, S., Meissner, J., Wilhelm, M., Koch, P., Lindemann, H.W., Schalk, E., Semrau, R., Kriz, J., Vieler, T., Bentz, M., Lange, E., Mahlberg, R., Hassler, A., Vogelhuber, M., Hahn, D., Mezger, J., Krause, S.W., Skoetz, N., Böll, B., von Tresckow, B., Diehl, V., Hallek, M., Borchmann, P., Stein, H., Eich, H. and Engert, A.
Lancet 385
(9976): 1418-1427.
11 April 2015
Structural identification of the VPS18 β-propeller reveals a critical role in the HOPS complex stability and function.
Behrmann, H., Lürick, A., Kuhlee, A., Kleine Balderhaar, H., Bröcker, C., Kümmel, D., Engelbrecht-Vandré, S., Gohlke, U., Raunser, S., Heinemann, U. and Ungermann, C.
Journal of Biological Chemistry 289
(48): 33503-33512.
28 November 2014
Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer.
Bei, Y., Brame, Luca, Kirchner, M., Fritsche-Guenther, R., Kunz, S., Bhattacharya, A., Rusu, M.C., Gürgen, D., Dubois, F.P.B., Köppke, J.K.C., Proba, J., Wittstruck, N., Sidorova, O.A., Chamorro González, R., Dorado Garcia, H., Brückner, L., Xu, R., Giurgiu, M., Rodriguez-Fos, E., Yu, Q., Spanjaard, B., Koche, R.P., Schmitt, C.A., Schulte, J.H., Eggert, A., Haase, K., Kirwan, J., Hagemann, A.I., Mertins, P., Dörr, J.R. and Henssen, A.G.
Cancer Discovery 14
(3): 492-507.
1 March 2024
Claudin-targeted suicide gene therapy for claudin-overexpressing tumor cells by using modified clostridium perfringens enterotoxin (CPE).
Beier, L.S., Piontek, J., Piontek, A., Protze, J., Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521
(3): 173-188.
23 June 2022
Upgrade of an optical navigation system with a permanent electromagnetic position control : A first step towards "navigated control" for liver surgery.
Beller, S., Eulenstein, S., Lange, T., Huenerbein, M. and Schlag, P.M.
Journal of Hepato-Biliary-Pancreatic Surgery 16
(2): 165-170.
March 2009
A new measure to assess the difficulty of liver resection.
Beller, S., Eulenstein, S., Lange, T., Niederstrasser, M., Huenerbein, M. and Schlag, P.M.
European Journal of Surgical Oncology 35
(1): 59-64.
January 2009
Feasibility of navigated resection of liver tumors using multiplanar visualization of intraoperative 3-dimensional ultrasound data.
Beller, S., Huenerbein, M., Eulenstein, S., Lange, T. and Schlag, P.M.
Annals of Surgery 246
(2): 288-294.
August 2007
Image-guided surgery of liver metastases by three-dimensional ultrasound-based optoelectronic navigation.
Beller, S., Huenerbein, M., Lange, T., Eulenstein, S., Gebauer, B. and Schlag, P.M.
British Journal of Surgery 94
(7): 866-875.
July 2007
Hat die palliative Resektion bei gastrointestinalen Tumoren noch einen Stellenwert? [Significance of palliative resection of gastrointestinal tumors.].
Beller, S. and Schlag, P.M.
Chirurg 77
: 219-226.
March 2006
CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.
Beltinger, C., Kurz, E., Boehler, T., Schrappe, M., Ludwig, W.D. and Debatin, K.M.
Blood 91
(10): 3943-3951.
15 May 1998
Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly.
Belz, K., Schoeneberger, H., Wehner, S., Weigert, A., Boenig, H., Klingebiel, T., Fichtner, I. and Fulda, S.
Blood 124
(2): 240-250.
10 July 2014
Impact of patient- and disease-specific factors on SLNB in breast cancer patients. Are current guidelines justified?
Bembenek, A., Fischer, J., Albrecht, H., Kemnitz, E., Gretschel, S., Schneider, U., Dresel, S. and Schlag, P.M.
World Journal of Surgery 31
(2): 267-275.
February 2007
Sentinel-Node-Biopsie : Definition, historische Entwicklung und methodisches Vorgehen.
Bembenek, A., Gretschel, S., Ulmer, C., Bayraktar, S. and Schlag, P.M.
Onkologe 9
(6): 599-610.
June 2003
Sentinel Lymph Node beim kolorektalen Karzinom [Sentinel lymph node biopsy in colorectal carcinoma].
Bembenek, A., Gretschel, S., Ulmer, C. and Schlag, P.M.
Chirurg 75
(8): 761-766.
1 January 2004
Presence of mature DC-Lamp(+) dendritic cells in sentinel and non-sentinel lymph nodes of breast cancer patients.
Bembenek, A., Li, J., Loddenkemper, C., Kemmner, W., Stein, H., Wernecke, K.D. and Schlag, P.M.
European Journal of Surgical Oncology 34
(5): 514-518.
May 2008
Sentinel lymph node biopsy in rectal cancer - not yet ready for routine clinical use.
Bembenek, A., Rau, B., Moesta, T., Markwardt, J., Ulmer, C., Gretschel, S., Schneider, U., Slisow, W. and Schlag, P.M.
Surgery 135
(5): 498-505.
May 2004
Detection of lymph node micrometastases and isolated tumor cells in sentinel and nonsentinel lymph nodes of colon cancer patients.
Bembenek, A., Schneider, U., Gretschel, S., Fischer, J. and Schlag, P.M.
World Journal of Surgery 29
: 1172-1175.
11 August 2005
Optimierung des Staging beim Kolonkarzinom durch Sentinel-Lymphknoten-Biopsie. Aktuelle Aspekte [Optimization of staging in colon cancer using sentinel lymph node biopsy].
Bembenek, A., Schneider, U., Gretschel, S., Ulmer, C. and Schlag, P.M.
Chirurg 76
(1): 58-67.
January 2005
Sentinel lymph node biopsy in colon cancer: A prospective multicenter trial.
Bembenek, A.E., Rosenberg, R., Wagler, E., Gretschel, S., Sendler, A., Siewert, J.R., Naehrig, J., Witzigmann, H., Hauss, J., Knorr, C., Dimmler, A., Groene, J., Buhr, H.J., Haier, J., Herbst, H., Tepel, J., Siphos, B., Kleespies, A., Koenigsrainer, A., Stoecklein, N.H., Horstmann, O., Gruetzmann, R., Imdahl, A., Svoboda, D., Wittekind, C., Schneider, W., Wernecke, K.D. and Schlag, P.M.
Annals of Surgery 245
(6): 858-863.
June 2007
A kinome of 2600 in the ciliate Paramecium tetraurelia.
Bemm, F., Schwarz, R., Foerster, F. and Schultz, J.
FEBS Letters 583
(22): 3589-3592.
19 November 2009
Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry.
Ben Hamza, A., Welters, C., Stadler, S., Brüggemann, M., Dietze, K., Brauns, O., Brümmendorf, T.H., Winkler, T.H., Bullinger, L., Blankenstein, T., Rosenberger, L., Leisegang, M., Kammertöns, T., Herr, W., Moosmann, A., Strobel, J., Hackstein, H., Dornmair, K., Beier, F. and Hansmann, L.
Blood 143
(14): 1365-1378.
4 April 2024
gen.ethix. Multimediales Online-Spiel zum aktuellen Bioethik-Diskurs.
Ben Salem, A.
BBB CampusNews
: 2.
1 January 2004
Modeling Wnt/β-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions.
Benary, U., Kofahl, B., Hecht, A. and Wolf, J.
Frontiers in Physiology 4
: 21.
25 February 2013
Disentangling pro-mitotic signaling during cell cycle progression using time-resolved single-cell imaging.
Benary, M., Bohn, S., Lüthen, M., Nolis, I.K., Blüthgen, N. and Loewer, A.
Cell Reports 31
(2): 107514.
14 April 2020
Leveraging large language models for decision support in personalized oncology.
Benary, M., Wang, X.D., Schmidt, M., Soll, D., Hilfenhaus, G., Nassir, M., Sigler, C., Knödler, M., Keller, U., Beule, D., Keilholz, U., Leser, U. and Rieke, D.T.
JAMA Network Open 6
(11): e2343689.
November 2023
Mathematical modelling of promoter occupancies in MYC-dependent gene regulation.
Benary, U., Wolf, E. and Wolf, J.
Genomics and Computational Biology 3
(2): e54.
2017
Controlling nuclear NF-κB dynamics by β-TrCP-insights from a computational model.
Benary, U. and Wolf, J.
Biomedicines 7
(2): 40.
27 May 2019
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.
Bendle, G.M., Linnemann, C., Hooijkaas, A.I., Bies, L., de Witte, M.A., Jorritsma, A., Kaiser, A.D.M., Pouw, N., Debets, R., Kieback, E., Uckert, W., Song, J.Y., Haanen, J.B.A.G. and Schumacher, T.N.M.
Nature Medicine 16
(5): 565-570, 1p following 570.
May 2010
The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias.
Bene, M.C., Bernier, M., Casasnovas, R.O., Castoldi, G., Knapp, W., Lanza, F., Ludwig, W.D., Matutes, E., Orfao, A., Sperling, C. and van't Veer, M.B.
Blood 92
(2): 596-599.
15 July 1998
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia.
Beneyto-Calabuig, S., Merbach, A.K., Kniffka, J.A., Antes, M., Szu-Tu, C., Rohde, C., Waclawiczek, A., Stelmach, P., Gräßle, S., Pervan, P., Janssen, M., Landry, J.J.M., Benes, V., Jauch, A., Brough, M., Bauer, M., Besenbeck, B., Felden, J., Bäumer, S., Hundemer, M., Sauer, T., Pabst, C., Wickenhauser, C., Angenendt, L., Schliemann, C., Trumpp, A., Haas, S., Scherer, M., Raffel, S., Müller-Tidow, C. and Velten, L.
Cell Stem Cell 30
(5): 706-721.
4 May 2023
The c-Myc/miR17-92/PTEN axis tunes PI3K activity to control expression of recombination activating genes in early B cell development.
Benhamou, D., Labi, V., Getahun, A., Benchetrit, E., Dowery, R., Rajewsky, K., Cambier, J.C. and Melamed, D.
Frontiers in Immunology 9
: 2715.
November 2018
A c-Myc/miR17-92/Pten axis controls PI3K-mediated positive and negative selection in B cell development and reconstitutes CD19 deficiency.
Benhamou, D., Labi, V., Novak, R., Dai, I., Shafir-Alon, S., Weiss, A., Gaujoux, R., Arnold, R., Shen-Orr, S.S., Rajewsky, K. and Melamed, D.
Cell Reports 16
(2): 419-431.
12 July 2016
Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues.
Benndorf, R., Gilmont, R.R., Hirano, S., Ransom, R.F., Jungblut, P.R., Bommer, M., Goldman, J.E. and Welsh, M.J.
Cell Stress & Chaperones 23
(5): 813-826.
September 2018
Therapie eines Zenker'schen Divertikels [Therapy of Zenker's divertikulum].
Benter, T., Kretzschmar, A., Reich, G., Papadopoulos, S., Kluhs, L., Ludwig, W.D. and Doerken, B.
Medizinische Klinik 97
(1): 44-45.
January 2002
Anatomical variations in the internal jugular veins of cancer patients affecting central venous access. Anatomical variation of the internal jugular vein.
Benter, T., Teichgraeber, U.K., Kluehs, L., Papadopoulos, S., Koehne, C.H., Felix, R. and Doerken, B.
Ultraschall in der Medizin 22
(1): 23-26.
February 2001
Using DNA sequencing data to quantify T cell fraction and therapy response.
Bentham, R., Litchfield, K., Watkins, T.B.K., Lim, E.L., Rosenthal, R., Martínez-Ruiz, C., Hiley, C.T., Bakir, M.A., Salgado, R., Moore, D.A., Jamal-Hanjani, M., Swanton, C. and McGranahan, N.
Nature 597
(7877): 555-560.
23 September 2021
The Cambridge jet algorithm: Features and applications.
Bentvelsen, S. and Meyer, I.M.
European Physical Journal C 4
(4): 623-629.
July 1998
Isolation of eosinophils from the lamina propria of the murine small intestine.
Berek, C., Beller, A. and Chu, V.T.
Methods in Molecular Biology 1422
: 213-221.
2016
Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia.
Berenstein, R., Blau, I.W., Suckert, N., Baldus, C., Pezzutto, A., Dörken, B. and Blau, O.
Journal of Experimental & Clinical Cancer Research 34
(1): 55.
22 May 2015
Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region.
Berenstein, R., Blau, O., Nogai, A., Waechter, M., Slonova, E., Schmidt-Hieber, M., Kunitz, A., Pezzutto, A., Doerken, B. and Blau, I.W.
BMC Cancer 15
(1): 68.
18 February 2015
Multiple myeloma cells modify VEGF/IL-6 levels and osteogenic potential of bone marrow stromal cells via Notch/miR-223.
Berenstein, R., Nogai, A., Waechter, M., Blau, O., Kuehnel, A., Schmidt-Hieber, M., Kunitz, A., Pezzutto, A., Dörken, B. and Blau, I.W.
Molecular Carcinogenesis 55
(12): 1927-1939.
December 2016
Structure of the Yersinia injectisome in intracellular host cell phagosomes revealed by cryo FIB electron tomography.
Berger, C., Ravelli, R.B.G., López-Iglesias, C., Kudryashev, M., Diepold, A. and Peters, P.J.
Journal of Structural Biology 213
(1): 107701.
March 2021
Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.
Bergman, A.M., Adema, A.D., Balzarini, J., Bruheim, S., Fichtner, I., Noordhuis, P., Fodstad, O., Myhren, F., Sandvold, M.L., Hendriks, H.R. and Peters, G.J.
Investigational New Drugs 29
(3): 456-466.
June 2011
YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification.
Bergmann, S., Royer-Pokora, B., Fietze, E., Juerchott, K., Hildebrandt, B., Trost, D., Leenders, F., Claude, J.C., Theuring, F., Bargou, R., Dietel, M. and Royer, H.D.
Cancer Research 65
(10): 4078-4087.
16 May 2005
Modelling the DNA topology: the effect of the loop bending on G-quadruplex stability.
Bergues-Pupo, A.E., Falo, F. and Fiasconaro, A.
Journal of Statistical Mechanics: Theory and Experiment 2019
(9): 094004.
2 September 2019
Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Berlak, M., Tucker, E., Dorel, M., Winkler, A., McGearey, A., Rodriguez-Fos, E., da Costa, B.M., Barker, K., Fyle, E., Calton, E., Eising, S., Ober, K., Hughes, D., Koutroumanidou, E., Carter, P., Stankunaite, R., Proszek, P., Jain, N., Rosswog, C., Dorado-Garcia, H., Molenaar, J.J., Hubank, M., Barone, G., Anderson, J., Lang, P., Deubzer, H.E., Künkele, A., Fischer, M., Eggert, A., Kloft, C., Henssen, A.G., Boettcher, M., Hertwig, F., Blüthgen, N., Chesler, L. and Schulte, J.H.
Molecular Cancer 21
(1): 126.
10 June 2022
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19.
Bernardes, J.P., Mishra, N., Tran, F., Bahmer, T., Best, L., Blase, J.I., Bordoni, D., Franzenburg, J., Geisen, U., Josephs-Spaulding, J., Köhler, P., Künstner, A., Rosati, E., Aschenbrenner, A.C., Bacher, P., Baran, N., Boysen, T., Brandt, B., Bruse, N., Dörr, J., Dräger, A., Elke, G., Ellinghaus, D., Fischer, J., Forster, M., Franke, A., Franzenburg, S., Frey, N., Friedrichs, A., Fuß, J., Glück, A., Hamm, J., Hinrichsen, F., Hoeppner, M.P., Imm, S., Junker, R., Kaiser, S., Kan, Y.H., Knoll, R., Lange, C., Laue, G., Lier, C., Lindner, M., Marinos, G., Markewitz, R., Nattermann, J., Noth, R., Pickkers, P., Rabe, K.F., Renz, A., Röcken, C., Rupp, J., Schaffarzyk, A., Scheffold, A., Schulte-Schrepping, J., Schunk, D., Skowasch, D., Ulas, T., Wandinger, K.P., Wittig, M., Zimmermann, J., Busch, H., Hoyer, B.F., Kaleta, C., Heyckendorf, J., Kox, M., Rybniker, J., Schreiber, S., Schultze, J.L. and Rosenstiel, P.
Immunity 53
(6): 1296-1314.
15 December 2020
Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer.
Berndt, N., Egners, A., Mastrobuoni, G., Vvedenskaya, O., Fragoulis, A., Dugourd, A., Bulik, S., Pietzke, M., Bielow, C., van Gassel, R., Olde Damink, S.W., Erdem, M., Saez-Rodriguez, J., Holzhütter, H.G., Kempa, S. and Cramer, T.
British Journal of Cancer 122
(2): 233-244.
21 January 2020
Quinols as novel therapeutic agents. 2.(1) 4-(1-arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.
Berry, J.M., Bradshaw, T.D., Fichtner, I., Ren, R., Schwalbe, C.H., Wells, G., Chew, E.H., Stevens, M.F. and Westwell, A.D.
Journal of Medicinal Chemistry 48
: 639-644.
27 January 2005
Proteomics of xenografted human breast cancer indicates novel targets related to tamoxifen resistance.
Besada, V., Diaz, M., Becker, M., Ramos, Y., Castellanos-Serra, L. and Fichtner, I.
Proteomics 6
(3): 1038-1048.
February 2006
Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
Besser, D., Bardelli, A., Didichenko, S., Thelen, M., Comoglio, P.M., Ponzetto, C. and Nagamine, Y.
Oncogene 14
(6): 705-711.
13 February 1997
A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.
Besser, D., Bromberg, J.F., Darnell, J.E. and Hanafusa, H.
Molecular and Cellular Biology 19
(2): 1401-1409.
February 1999
DNA methylation inhibits transcription by RNA polymerase III of a tRNA gene, but not of a 5S rRNA gene.
Besser, D., Goetz, F., Schulze-Forster, K., Wagner, H., Kroeger, H. and Simon, D.
FEBS Letters 269
(2): 358-362.
3 September 1990
Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts.
Besser, D., Presta, M. and Nagamine, Y.
Cell Growth & Differentiation 6
(8): 1009-1017.
August 1995
Urokinase-type plasminogen activator gene regulation by polyomavirus middle-T antigen.
Besser, D., Urich, M., Sakaue, M., Messerschmitt, A., Ballmer-Hofer, K. and Nagamine, Y.
Oncogene 11
(11): 2383-2391.
7 December 1995
Signal transduction and the u-PA/u-PAR system.
Besser, D., Verde, P., Nagamine, Y. and Blasi, F.
Fibrinolysis 10
(4): 215-237.
July 1996
Expression of nodal, lefty-A, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.
Besser, D.
Journal of Biological Chemistry 279
(43): 45076-45084.
1 January 2004
Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune, M.T., Gee, M.H., Bunse, M., Lee, M.S., Gschweng, E.H., Pagadala, M.S., Zhou, J., Cheng, D., Heath, J.R., Kohn, D.B., Kuhns, M.S., Uckert, W. and Baltimore, D.
eLife 5
: e19095.
8 November 2016
Molecular dynamics simulations of the 136 unique tetranucleotide sequences of DNA oligonucleotides.
Beveridge, D.L., Barreiro, G., Byun, S.K., Case, D.A., Cheatham, T.E., Dixit, S.B., Giudice, E., Lankas, F., Lavery, R., Maddocks, J.H., Osman, R., Seibert, E., Sklenar, H., Stoll, G., Thayer, K.M., Varnai, P. and Young, M.A.
Biophysical Journal 87
(6): 3799-3813.
December 2004
Clinical features and outcome of children with first marrow relapse of acute lymphoblastic leukemia expressing BCR-ABL fusion transcripts.
Beyermann, B., Agthe, A.G., Adams, H.P., Seeger, K., Linderkamp, C., Goetze, G., Ludwig, W.D. and Henze, G.
Blood 87
(4): 1532-1538.
15 February 1996
Conformation and stability of the Streptococcus pyogenes pSM19035-encoded site-specific beta recombinase, and identification of a folding intermediate.
Bhardwaj, A., Welfle, K., Misselwitz, R., Ayora, S., Alonso, J.C. and Welfle, H.
Biological Chemistry 387
(5): 525-533.
May 2006
Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.
Bhaskara, R.M., Grumati, P., Garcia-Pardo, J., Kalayil, S., Covarrubias-Pinto, A., Chen, W., Kudryashev, M., Dikic, I. and Hummer, G.
Nature Communications 10
(1): 2370.
30 May 2019
DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis.
Bhonde, M.R., Hanski, M.L., Budczies, J., Cao, M., Gillissen, B., Moorthy, D., Simonetta, F., Scheruebl, H., Truss, M., Hagemeier, C., Mewes, H.W., Daniel, P.T., Zeitz, M. and Hanski, C.
Journal of Biological Chemistry 281
: 8675-8685.
31 March 2006
The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein.
Bhonde, M.R., Hanski, M.L., Magrini, R., Moorthy, D., Mueller, A., Sausville, E.A., Kohno, K., Wiegand, P., Daniel, P.T., Zeitz, M. and Hanski, C.
Oncogene 24
: 148-156.
6 January 2005
Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.
Bhonde, M.R., Hanski, M.L., Notter, M., Gillissen, B.F., Daniel, P.T., Zeitz, M. and Hanski, C.
Oncogene 25
: 165-175.
12 January 2006
Replicative aging and differentiation potential of human adipose tissue-derived mesenchymal stromal cells expanded in pooled human or fetal bovine serum.
Bieback, K., Hecker, A., Schlechter, T., Hofmann, I., Brousos, N., Redmer, T., Besser, D., Klueter, H., Mueller, A.M. and Becker, M.
Cytotherapy 14
(5): 570-583.
May 2012
SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
Biederstädt, A., Hassan, Z., Schneeweis, C., Schick, M., Schneider, L., Muckenhuber, A., Hong, Y., Siegers, G., Nilsson, L., Wirth, M., Dantes, Z., Steiger, K., Schunck, K., Langston, S., Lenhof, H.P., Coluccio, A., Orben, F., Slawska, J., Scherger, A., Saur, D., Müller, S., Rad, R., Weichert, W., Nilsson, J., Reichert, M., Schneider, G. and Keller, U.
Gut 69
(8): 1472-1482.
August 2020
Skin-resident innate lymphoid cells converge on a pathogenic effector state.
Bielecki, P., Riesenfeld, S.J., Hütter, J.C., Torlai Triglia, E., Kowalczyk, M.S., Ricardo-Gonzalez, R.R., Lian, M., Amezcua Vesely, M.C., Kroehling, L., Xu, H., Slyper, M., Muus, C., Ludwig, L.S., Christian, E., Tao, L., Kedaigle, A.J., Steach, H.R., York, A.G., Skadow, M.H., Yaghoubi, P., Dionne, D., Jarret, A., McGee, H.M., Porter, C.B.M., Licona-Limón, P., Bailis, W., Jackson, R., Gagliani, N., Gasteiger, G., Locksley, R.M., Regev, A. and Flavell, R.A.
Nature 592
(7852): 128-132.
1 April 2021
On mass ambiguities in high-resolution shotgun lipidomics.
Bielow, C., Mastrobuoni, G., Orioli, M. and Kempa, S.
Analytical Chemistry 89
(5): 2986-2994.
7 March 2017
Radioimmunotherapy using 131I-rituximab in patients with advanced stage B-cell non-Hodgkin's lymphoma: initial experience.
Bienert, M., Reisinger, I., Srock, S., Humplik, B.I., Reim, C., Kroessin, T., Avril, N., Pezzutto, A. and Munz, D.L.
European Journal of Nuclear Medicine and Molecular Imaging 32
: 1225-1233.
1 January 2005
Crystal structure of NblA from Anabaena sp. PCC 7120, a small protein playing a key role in phycobilisome degradation.
Bienert, R., Baier, K., Volkmer, R., Lockau, W. and Heinemann, U.
Journal of Biological Chemistry 281
(8): 5216-5223.
24 February 2006
Single-stranded DNA bound to bacterial cold-shock proteins: preliminary crystallographic and Raman analysis.
Bienert, R., Zeeb, M., Dostal, L., Feske, A., Magg, C., Max, K., Welfle, H., Balbach, J. and Heinemann, U.
Acta Crystallographica Section D 60
(4): 755-757.
1 January 2004
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer.
Bigl, M., Jandrig, B., Horn, L.C. and Eschrich, K.
Biochemical and Biophysical Research Communications 377
(2): 720-724.
12 December 2008
In vitro activity and mechanism of action of a duplex and multidrug of ethynylcytidine and 5-fluorodeoxyuridine.
Bijnsdorp, I., Schwendener, R., Schott, H., Schott, S., Fichtner, I., Honeywell, R., Losekoot, N., Laan, A. and Peters, G.J.
Nucleic Acids Symposium Series 52
: 651.
8 September 2008
Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.
Bijnsdorp, I.V., Schwendener, R.A., Schott, H., Fichtner, I., Smid, K., Laan, A.C., Schott, S., Losekoot, N., Honeywell, R.J. and Peters, G.J.
Investigational New Drugs 29
(2): 248-257.
April 2011
In vivo and in vitro activity and mechanism of action of the multidrug cytarabine-L-glycerylyl-fluorodeoxyuridine.
Bijnsdorp, I.V., Schwendener, R.A., Schott, H., Fichtner, I., Smid, K., Schott, S., Laan, A.C. and Peters, G.J.
Nucleosides Nucleotides & Nucleic Acids 26
(10-12): 1619-1624.
5 December 2007
Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.
Bilic, I., Koesters, C., Unger, B., Sekimata, M., Hertweck, A., Maschek, R., Wilson, C.B. and Ellmeier, W.
Nature Immunology 7
(4): 392-400.
April 2006
Hormonal induction of functional differentiation and mammary-derived growth inhibitor expression in cultured mouse mammary gland explants.
Binas, B., Spitzer, E., Zschiesche, W., Erdmann, B., Kurtz, A., Mueller, T., Niemann, C., Blenau, W. and Grosse, R.
In Vitro Cellular & Developmental Biology 28A
(9-10): 625-634.
September 1992
Tailoring sparse multivariable regression techniques for prognostic single-nucleotide polymorphism signatures.
Binder, H., Benner, A., Bullinger, L. and Schumacher, M.
Statistics in Medicine 32
(10): 1778-91.
10 May 2013
Identification and functional characterization of hypoxia-induced endoplasmic reticulum stress regulating lncRNA (HypERlnc) in pericytes.
Bischoff, F.C., Werner, A., John, D., Boeckel, J.-N., Melissari, M.-T., Grote, P., Glaser, S.F., Demolli, S., Uchida, S., Michalik, K.M., Meder, B., Katus, H.A., Haas, J., Chen, W., Pullamsetti, S.S., Seeger, W., Zeiher, A.M., Dimmeler, S. and Zehendner, C.M.
Circulation Research 121
(4): 368-375.
4 August 2017
The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing.
Bischoff, N., Wimberger, S., Kuehn, R., Laugesen, A., Turan, V., Larsen, B.D., Sørensen, C.S., Helin, K., Bennett, E.P., Maresca, M. and Brakebusch, C.
Gene and Genome Editing 5
: 100023.
June 2023
Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R., Dickinson, M., Purtill, D., Barba, P., Santoro, A., Hamad, N., Kato, K., Sureda, A., Greil, R., Thieblemont, C., Morschhauser, F., Janz, M., Flinn, I., Rabitsch, W., Kwong, Y.L., Kersten, M.J, Minnema, M.C., Holte, H., Chan, E.H.L., Martinez-Lopez, J., Müller, A.M.S., Maziarz, R.T., McGuirk, J.P., Bachy, E., Le Gouill, S., Dreyling, M., Harigae, H., Bond, D., Andreadis, C., McSweeney, P., Kharfan-Dabaja, M., Newsome, S., Degtyarev, E., Awasthi, R., Del Corral, C., Andreola, G., Masood, A., Schuster, S.J., Jäger, U., Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386
(7): 629-639.
17 February 2022
Spectroelectrochemistry of cytochrome P450cam.
Bistolas, N., Christenson, A., Ruzgas, T., Jung, C., Scheller, F.W. and Wollenberger, U.
Biochemical and Biophysical Research Communications 314
(3): 810-816.
13 February 2004
A clonal expression biomarker associates with lung cancer mortality.
Biswas, D., Birkbak, N.J., Rosenthal, R., Hiley, C.T., Lim, E.L., Papp, K., Boeing, S., Krzystanek, M., Djureinovic, D., La Fleur, L., Greco, M., Döme, B., Fillinger, J., Brunnström, H., Wu, Y., Moore, D.A., Skrzypski, M., Abbosh, C., Litchfield, K., Al Bakir, M., Watkins, T.B.K., Veeriah, S., Wilson, G.A., Jamal-Hanjani, M., Moldvay, J., Botling, J., Chinnaiyan, A.M., Micke, P., Hackshaw, A., Bartek, J., Csabai, I., Szallasi, Z., Herrero, J., McGranahan, N. and Swanton, C.
Nature Medicine 25
(10): 1540-1548.
October 2019
Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.
Blackburn, J., Kawasaki, K., Porntaveetus, T., Kawasaki, M., Otsuka-Tanaka, Y., Miake, Y., Ota, M.S., Watanabe, M., Hishinuma, M., Nomoto, T., Oommen, S., Ghafoor, S., Harada, F., Nozawa-Inoue, K., Maeda, T., Peterkova, R., Lesot, H., Inoue, J., Akiyama, T., Schmidt-Ullrich, R., Liu, B., Hu, Y., Page, A., Ramirez, A., Sharpe, P.T. and Ohazama, A.
Journal of Dental Research 94
(1): 121-128.
January 2015
The role of Irf6 in tooth epithelial invagination.
Blackburn, J., Ohazama, A., Kawasaki, K., Otsuka-Tanaka, Y., Liu, B., Honda, K., Rountree, R.B., Hu, Y., Kawasaki, M., Birchmeier, W., Schmidt-Ullrich, R., Kinoshita, A., Schutte, B.C., Hammond, N.L., Dixon, M.J. and Sharpe, P.T.
Developmental Biology 365
(1): 61-70.
1 May 2012
Identification and ranking of recurrent neo-epitopes in cancer.
Blanc, E., Holtgrewe, M., Dhamodaran, A., Messerschmidt, C., Willimsky, G., Blankenstein, T. and Beule, D.
BMC Medical Genomics 12
: 171.
27 November 2019
High-throughput omics technologies: Potential tools for the investigation of influences of EMF on biological systems.
Blankenburg, M., Haberland, L., Elvers, H.D., Tannert, C. and Jandrig, B.
Current Genomics 10
(2): 86-92.
April 2009
Spontaneous and therapy-induced T cell responses to cancer.
Blankenstein, T.
Arzneimittelforschung 62
(1): S9.
November 2012
The determinants of tumour immunogenicity.
Blankenstein, T., Coulie, P.G., Gilboa, E. and Jaffee, E.M.
Nature Reviews Cancer 12
(4): 307-313.
April 2012
Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition.
Blattmann, C., Oertel, S., Ehemann, V., Thiemann, M., Huber, P.E., Bischof, M., Witt, O., Deubzer, H.E., Kulozik, A.E., Debus, J. and Weber, K.J.
International Journal of Radiation Oncology, Biology, Physics 78
(1): 237-245.
1 September 2010
The translocation motif of hepatitis B virus improves protein vaccination.
Bleifuss, E., Kammertoens, T., Hutloff, A., Quarcoo, D., Dorner, M., Straub, P., Uckert, W. and Hildt, E.
Cellular and Molecular Life Sciences 63
: 627-635.
March 2006
Systemic inflammation and normocytic anemia in DOCK11 deficiency.
Block, J., Rashkova, C., Castanon, I., Zoghi, S., Platon, J., Ardy, R.C., Fujiwara, M., Chaves, B., Schoppmeyer, R., van der Made, C.I., Jimenez Heredia, R., Harms, F.L., Alavi, S., Alsina, L., Sanchez Moreno, P., Ávila Polo, R., Cabrera-Pérez, R., Kostel Bal, S., Pfajfer, L., Ransmayr, B., Mautner, A.K., Kondo, R., Tinnacher, A., Caldera, M., Schuster, M., Domínguez Conde, C., Platzer, R., Salzer, E., Boyer, T., Brunner, H.G., Nooitgedagt-Frons, J.E., Iglesias, E., Deyà-Martinez, A., Camacho-Lovillo, M., Menche, J., Bock, C., Huppa, J.B., Pickl, W.F., Distel, M., Yoder, J.A., Traver, D., Engelhardt, K.R., Linden, T., Kager, L., Hannich, J.T., Hoischen, A., Hambleton, S., Illsinger, S., Da Costa, L., Kutsche, K., Chavoshzadeh, Z., van Buul, J.D., Antón, J., Calzada-Hernández, J., Neth, O., Viaud, J., Nishikimi, A., Dupré, L. and Boztug, K.
New England Journal of Medicine 389
(6): 527-539.
10 August 2023
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Bloehdorn, J., Braun, A., Taylor-Weiner, A., Jebaraj, B.M.C., Robrecht, S., Krzykalla, J., Pan, H., Giza, A., Akylzhanova, G., Holzmann, K., Scheffold, A., Johnston, H.E., Yeh, R.F., Klymenko, T., Tausch, E., Eichhorst, B., Bullinger, L., Fischer, K., Weisser, M., Robak, T., Schneider, C., Gribben, J., Dahal, L.N., Carter, M.J., Elemento, O., Landau, D.A., Neuberg, D.S., Cragg, M.S., Benner, A., Hallek, M., Wu, C.J., Döhner, H., Stilgenbauer, S. and Mertens, D.
Nature Communications 12
(1): 5395.
13 September 2021
CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J., Kieback, E., Marino, S.F., Oden, F., Westermann, J., Chmielewski, M., Abken, H., Uckert, W., Höpken, U.E. and Rehm, A.
Molecular Therapy 26
(8): 1906-1920.
1 August 2018
Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T., Funck, K., Wollweber, F., Lisicki, E., von der Malsburg, K., von der Malsburg, A., Laborenz, J., Noel, J.K., Hessenberger, M., Jungbluth, S., Bernert, C., Kunz, S., Riedel, D., Lilie, H., Jakobs, S., van der Laan, M. and Daumke, O.
Science Advances 8
(35): eabo4946.
2 September 2022
Microsatellite instability analysis: a multicenter study for reliability and quality control.
Bocker, T., Diermann, J., Friedl, W., Gebert, J., Holinski-Feder, E., Karner-Hanusch, J., von Knebel-Doeberitz, M., Koelble, K., Moeslein, G., Schackert, H.K., Witz, H.C., Fishel, R. and Rueschoff, J.
Cancer Research 57
(21): 4739-4743.
1 November 1997
SLM2 is a novel cardiac splicing factor involved in heart failure due to dilated cardiomyopathy.
Boeckel, J.N., Möbius-Winkler, M., Müller, M., Rebs, S., Eger, N., Schoppe, L., Tappu, R., Kokot, K.E., Kneuer, J.M., Gaul, S., Bordalo, D.M., Lai, A., Haas, J., Ghanbari, M., Drewe-Boss, P., Liss, M., Katus, H.A., Ohler, U., Gotthardt, M., Laufs, U., Streckfuss-Bömeke, K. and Meder, B.
Genomics Proteomics & Bioinformatics 20
(1): 129-146.
February 2022
Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N., Perret, M.F., Glaser, S.F., Seeger, T., Heumüller, A.W., Chen, W., John, D., Kokot, K.E., Katus, H.A., Haas, J., Lackner, M.K., Kayvanpour, E., Grabe, N., Dieterich, C., von Haehling, S., Ebner, N., Hünecke, S., Leuschner, F., Fichtlscherer, S., Meder, B., Zeiher, A.M., Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126
: 13-22.
January 2019
The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A., Babila, J.T., Wiglenda, T., Diez, L., Jacob, M., Nietfeld, W., Huska, M.R., Haenig, C., Groenke, N., Buntru, A., Blanc, E., Meier, J.C., Vannoni, E., Erck, C., Friedrich, B., Martens, H., Neuendorf, N., Schnoegl, S., Wolfer, D.P., Loos, M., Beule, D., Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26
(1): 109-120.
17 January 2019
A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y., Malehmir, M., Healy, M.E., Bettermann, K., Lorentzen, A., Vucur, M., Ahuja, A.K., Böhm, F., Mertens, J.C., Shimizu, Y., Frick, L., Remouchamps, C., Mutreja, K., Kähne, T., Sundaravinayagam, D., Wolf, M.J., Rehrauer, H., Koppe, C., Speicher, T., Padrissa-Altés, S., Maire, R., Schattenberg, J.M., Jeong, J.S., Liu, Lei, Zwirner, S., Boger, R., Hüser, N., Davis, R.J., Müllhaupt, B., Moch, H., Schulze-Bergkamen, H., Clavien, P.A., Werner, S., Borsig, L., Luther, S.A., Jost, P.J., Weinlich, R., Unger, K., Behrens, A., Hillert, L., Dillon, C., Di Virgilio, M., Wallach, D., Dejardin, E., Zender, L., Naumann, M., Walczak, H., Green, D.R., Lopes, M., Lavrik, I., Luedde, T., Heikenwalder, M. and Weber, A.
Cancer Cell 32
(3): 342-359.
11 September 2017
Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme.
Boehm, K., Herter, T., Mueller, J.J., Borriss, R. and Heinemann, U.
FEBS Journal 277
(5): 1284-1296.
March 2010
Dendritic cell progenitor is transformed by a conditional v-rel estrogen receptor fusion v-relER.
Boehmelt, G., Madruga, J., Doerfler, P., Briegel, K., Schwarz, H., Enrietto, P. and Zenke, M.
Cell 80
(2): 341-352.
27 January 1995
Hormone-regulated v-rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression.
Boehmelt, G., Walker, A., Kabrun, N., Mellitzer, G., Beug, H., Zenke, M. and Enrietto, P.J.
EMBO Journal 11
(12): 4641-4652.
December 1992
Visceral leishmaniasis diagnosis and reporting delays as an obstacle to timely response actions in Nepal and India.
Boettcher, J.P., Siwakoti, Y., Milojkovic, A., Siddiqui, N.A., Gurung, C.K., Rijal, S., Das, P., Kroeger, A. and Banjara, M.R.
BMC Infectious Diseases 15
(1): 43.
6 February 2015
Combining metabolic pulse labeling and quantitative proteomics to monitor protein synthesis upon viral infection.
Bogdanow, B., Katsimani, N., Liu, F. and Selbach, M.
Methods in Molecular Biology 2610
: 149-165.
2023
Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis.
Bogdanow, B., Schmidt, M., Weisbach, H., Gruska, I., Vetter, B., Imami, K., Ostermann, E., Brune, W., Selbach, M., Hagemeier, C. and Wiebusch, L.
Nature Communications 11
(1): 4845.
24 September 2020
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B., Wang, X., Eichelbaum, K., Sadewasser, A., Husic, I., Paki, K., Budt, M., Hergeselle, M., Vetter, B., Hou, J., Chen, W., Wiebusch, L., Meyer, I.M., Wolff, T. and Selbach, M.
Nature Communications 10
(1): 5518.
4 December 2019
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska, R., Mikecin, A.M., Kaschutnig, P., Fawaz, M., Büchler-Schäff, M., Le, D., Ganuza, M., Vollmer, A., Paffenholz, S.V., Asada, N., Rodriguez-Correa, E., Frauhammer, F., Buettner, F., Ball, M., Knoch, J., Stäble, S., Walter, D., Petri, A., Carreño-Gonzalez, M.J., Wagner, V., Brors, B., Haas, S., Lipka, D.B., Essers, M.A.G., Weru, V., Holland-Letz, T., Mallm, J.P., Rippe, K., Krämer, S., Schlesner, M., McKinney Freeman, S., Florian, M.C., King, K.Y., Frenette, P.S., Rieger, M.A. and Milsom, M.D.
Cell Stem Cell 29
(8): 1273-1284.
4 August 2022
New targeted agents in acute myeloid leukemia: new hope on the rise.
Bohl, S.R., Bullinger, L. and Rücker, F.G.
International Journal of Molecular Sciences 20
(8)
23 April 2019
Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma.
Bohl, S.R., Schmalbrock, L.K., Bauhuf, I., Meyer, T., Dolnik, A., Szyska, M., Blätte, T.J., Knödler, S., Röhner, L., Miller, D., Kull, M., Langer, C., Döhner, H., Letai, A., Damm, F., Heckl, D., Bullinger, L. and Krönke, J.
Blood Advances 5
(9): 2391-2402.
11 May 2021
Cytolysis of leukemic B-cells by T-cells activated via 2 bispecific antibodies.
Bohlen, H., Manzke, O., Patel, B., Moldenhauer, G., Doerken, B., von Fliedner, V., Diehl, V. and Tesch, H.
Cancer Research 53
(18): 4310-4314.
15 September 1993
Treatment of brain metastases in patients with testicular cancer.
Bokemeyer, C., Nowak, P., Haupt, A., Metzner, B., Koehne, H., Hartmann, J.T., Kanz, L. and Schmoll, H.J.
Journal of Clinical Oncology 15
(4): 1449-1454.
April 1997
Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N., Bader, M., Willnow, T.E., Wiedenmann, B. and Sigal, M.
Frontiers in Endocrinology 15
: 1331231.
17 April 2024
CAFE: an R package for the detection of gross chromosomal abnormalities from gene expression microarray data.
Bollen, S., Leddin, M., Andrade-Navarro, M.A. and Mah, N.
Bioinformatics 30
(10): 1484-1485.
15 May 2014
Prognoserelevanz von biologischen und molekularen Markern in der Onkologie : Kriterien fur Studienplanung und -Interpretation. [Prognostic relevance of biological and molecular markers in oncology. Criteria for planning and interpreting studies].
Bollschweiler, E., Schneider, P.M., Moenig, S.P., Altendorf-Hofmann, A., Mansmann, U., Lehmacher, W., Schlag, P.M., Merkel, S., Hohenberger, W., Izbicki, J.R., Hermanek, P. and Hoelscher, A.H.
Chirurg 74
(2): 139-144.
February 2003
VISOR: a versatile haplotype-aware structural variant simulator for short- and long-read sequencing.
Bolognini, D., Sanders, A., Korbel, J.O., Magi, A., Benes, V. and Rausch, T.
Bioinformatics 36
(4): 1267-1269.
15 February 2020
ICOS+Th cells produce distinct cytokines in different mucosal immune responses.
Bonhagen, K., Liesenfeld, O., Stadecker, M.J., Hutloff, A., Erb, K., Coyle, A.J., Lipp, M., Kroczek, R.A. and Kamradt, T.
European Journal of Immunology 33
(2): 392-401.
February 2003
Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors.
Bonifacius, A., Lamottke, B., Tischer-Zimmermann, S., Schultze-Florey, R., Goudeva, L., Heuft, H.G., Arseniev, L., Beier, R., Beutel, G., Cario, G., Fröhlich, B., Greil, J., Hansmann, L., Hasenkamp, J., Höfs, M., Hundsdoerfer, P., Jost, E., Kafa, K., Kriege, O., Kröger, N., Mathas, S., Meisel, R., Nathrath, M., Putkonen, M., Ravens, S., Reinhardt, H.C., Sala, E., Sauer, M.G, Schmitt, C., Schroers, R., Steckel, N.K., Trappe, R.U., Verbeek, M., Wolff, D., Blasczyk, R., Eiz-Vesper, B. and Maecker-Kolhoff, B.
Journal of Clinical Investigation 133
(12): e163548.
15 June 2023
Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy.
Boogerd, C.J., Lacraz, G.P.A., Vértesy, Á., van Kampen, S.J., Perini, I., de Ruiter, H., Versteeg, D., Brodehl, A., van der Kraak, P., Giacca, M., de Jonge, N., Junker, J.P., van Oudenaarden, A., Vink, A. and van Rooij, E.
Cardiovascular Research 119
(2): 477-491.
February 2023
Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial.
Borchmann, P., Ferdinandus, J., Schneider, G., Moccia, A., Greil, R., Hertzberg, M., Schaub, V., Hüttmann, A., Keil, F., Dierlamm, J., Hänel, M., Novak, U., Meissner, J., Zimmermann, A., Mathas, S., Zijlstra, J.M., Fosså, A., Viardot, A., Hertenstein, B., Martin, S., Giri, P., Scholl, S., Topp, M.S., Jung, W., Vucinic, V., Beck, H.J., Kerkhoff, A., Unger, B., Rank, A., Schroers, R., zum Büschenfelde, C.M., de Wit, M., Trautmann-Grill, K., Kamper, P., Molin, D., Kreissl, S., Kaul, H., von Tresckow, B., Borchmann, S., Behringer, K., Fuchs, M., Rosenwald, A., Klapper, W., Eich, H.T., Baues, C., Zomas, A., Hallek, M., Dietlein, M., Kobe, C. and Diehl, V.
Lancet 404
(10450): 341-352.
27 July 2024
Eight cycles of escalated-dose BEACOPP compared with four cycles of escalated-dose BEACOPP followed by four cycles of baseline-dose BEACOPP with or without radiotherapy in patients with advanced-stage Hodgkin's lymphoma: final analysis of the HD12 trial of the German Hodgkin study group.
Borchmann, P., Haverkamp, H., Diehl, V., Cerny, T., Markova, J., Ho, A.D., Eich, H.T., Mueller-Hermelink, H.K., Kanz, L., Greil, R., Rank, A., Paulus, U., Smardova, L., Huber, C., Doerken, B., Nerl, C., Krause, S.W., Mueller, R.P., Fuchs, M. and Engert, A.
Journal of Clinical Oncology 29
(32): 4234-4342.
10 November 2011
PET-guided omission of radiotherapy in early-stage unfavourable Hodgkin lymphoma (GHSG HD17): a multicentre, open-label, randomised, phase 3 trial.
Borchmann, P., Plütschow, A., Kobe, C., Greil, R., Meissner, J., Topp, M.S., Ostermann, H., Dierlamm, J., Mohm, J., Thiemer, J., Sökler, M., Kerkhoff, A., Ahlborn, M., Halbsguth, T.V., Martin, S., Keller, U., Balabanov, S., Pabst, T., Vogelhuber, M., Hüttmann, A., Wilhelm, M., Zijlstra, J.M., Moccia, A., Kuhnert, G., Bröckelmann, P.J., von Tresckow, B., Fuchs, M., Klimm, B., Rosenwald, A., Eich, H., Baues, C., Marnitz, S., Hallek, M., Diehl, V., Dietlein, M. and Engert, A.
Lancet Oncology 22
(2): 223-234.
February 2021
WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N., Gloaguen, Y., Opialla, T., Blanc, E., Sicard, E., Royer, A.L., Le Bizec, B., Durand, S., Migné, C., Pétéra, M., Pujos-Guillot, E., Giacomoni, F., Guitton, Y., Beule, D. and Kirwan, J.
Metabolites 9
(9): 171.
21 August 2019
Mitochondrial membrane potential is dependent on the oligomeric state of F1F0-ATP synthase supracomplexes.
Bornhoevd, C., Vogel, F., Neupert, W. and Reichert, A.S.
Journal of Biological Chemistry 281
(20): 13990-13998.
19 May 2006
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G., Kleinewietfeld, M., Di Mitri, D., Sternjak, A., Diamantini, A., Giometto, R., Hoepner, S., Centonze, D., Bernardi, G., Dell'Acqua, M.L., Rossini, P.M., Battistini, L., Roetzschke, O. and Falk, K.
Blood 110
(4): 1225-1232.
15 August 2007
Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Bothmer, A., Robbiani, D.F., Di Virgilio, M., Bunting, S.F., Klein, I.A., Feldhahn, N., Barlow, J., Chen, H.T., Bosque, D., Callen, E., Nussenzweig, A. and Nussenzweig, M.C.
Molecular Cell 42
(3): 319-329.
6 May 2011
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.
Bouchard, C., Lee, S., Paulus-Hock, V., Loddenkemper, C., Eilers, M. and Schmitt, C.A.
Genes & Development 21
(21): 2775-2787.
1 November 2007
Single-cell time series analysis reveals the dynamics of HSPC response to inflammation.
Bouman, B.J., Demerdash, Y., Sood, S., Grünschläger, F., Pilz, F., Itani, A.R., Kuck, A., Marot-Lassauzaie, V., Haas, S., Haghverdi, L. and Essers, M.A.
Life Science Alliance 7
(3): e202302309.
March 2024
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Bowl, M.R., Simon, M.M., Ingham, N.J., Greenaway, S., Santos, L., Cater, H., Taylor, S., Mason, J., Kurbatova, N., Pearson, S., Bower, L.R., Clary, D.A., Meziane, H., Reilly, P., Minowa, O., Kelsey, L., Tocchini-Valentini, G.P., Gao, X., Bradley, A., Skarnes, W.C., Moore, M., Beaudet, A.L., Justice, M.J., Seavitt, J., Dickinson, M.E., Wurst, W., Hrabe de Angelis, M., Herault, Y., Wakana, S., Nutter, L.M.J., Flenniken, A.M., McKerlie, C., Murray, S.A., Svenson, K.L., Braun, R.E., West, D.B., Lloyd, K.C.K., Adams, D.J., White, J., Karp, N., Flicek, P., Smedley, D., Meehan, T.F., Parkinson, H.E., Teboul, L.M., Wells, S., Steel, K.P., Mallon, A.M. and Brown, S.D.M.
Nature Communications 8
(1): 886.
12 October 2017
Neurogenic amplification of immune complex inflammation.
Bozic, C.R., Lu, B., Höpken, U.E., Gerard, C. and Gerard, N.P.
Science 273
(5282): 1722-1725.
20 September 1996
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Bracken, A.P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Moench, K., Minucci, S., Porse, B.T., Marine, J.-C., Hansen, K.H. and Helin, K.
Genes & Development 21
(5): 525-530.
1 March 2007
Efficacy of MS-275, a selective inhibitor of class I histone deacetylases, in human colon cancer models.
Bracker, T.U., Sommer, A., Fichtner, I., Faus, H., Haendler, B. and Hess-Stumpp, H.
International Journal of Oncology 35
(4): 909-920.
October 2009
A high-resolution root spatiotemporal map reveals dominant expression patterns.
Brady, S.M., Orlando, D.A., Lee, J.Y., Wang, J.Y., Koch, J., Dinneny, J.R., Mace, D., Ohler, U. and Benfey, P.N.
Science 318
(5851): 801-806.
2 November 2007
A stele-enriched gene regulatory network in the Arabidopsis root.
Brady, S.M., Zhang, L., Megraw, M., Martinez, N.J., Jiang, E., Yi, C.S., Liu, W., Zeng, A., Taylor-Teeples, M., Kim, D., Ahnert, S., Ohler, U., Ware, D., Walhout, A.J.M. and Benfey, P.N.
Molecular Systems Biology 7
: 459.
18 January 2011
Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M., Lee, S., Loddenkemper, C., Rudolph, C., Peters, A.H., Schlegelberger, B., Stein, H., Doerken, B., Jenuwein, T. and Schmitt, C.A.
Nature 436
(7051): 660-665.
4 August 2005
Conditioning with fludarabine and treosulfan compared to FLAMSA-RIC in allogeneic stem cell transplantation for myeloid malignancies: a retrospective single-center analysis.
Braitsch, K., Schwarz, A., Koch, K., Hubbuch, M., Menzel, H., Keller, U., Götze, K.S., Bassermann, F., Herhaus, P. and Verbeek, M.
Annals of Hematology 101
(6): 1311-1319.
June 2022
Monomeric TCRs drive T cell antigen recognition.
Brameshuber, M., Kellner, F., Rossboth, B.K., Ta, H., Alge, K., Sevcsik, E., Göhring, J., Axmann, M., Baumgart, F., Gascoigne, N.R.J., Davis, S.J., Stockinger, H., Schütz, G.J. and Huppa, J.B.
Nature Immunology 19
(5): 487-496.
May 2018
A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand, J., Smith, E.S.J., Schwefel, D., Lapatsina, L., Poole, K., Omerbasic, D., Kozlenkov, A., Behlke, J., Lewin, G.R. and Daumke, O.
EMBO Journal 31
(17): 3635-3646.
29 August 2012
Impact of a specialised palliative care intervention in patients with advanced soft tissue sarcoma - a single-centre retrospective analysis.
Brandes, F., Striefler, J.K., Dörr, A., Schmiester, M., Märdian, S., Koulaxouzidis, G., Kaul, D., Behzadi, A., Thuss-Patience, P., Ahn, J., Pelzer, U., Bullinger, L. and Flörcken, A.
BMC Palliative Care 20
(1): 16.
14 January 2021
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
Brandl, C., Ortiz, O., Röttig, B., Wefers, B., Wurst, W. and Kühn, R.
FEBS Open Bio 5
: 26-35.
2015
Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.
Braten, O., Livneh, I., Ziv, T., Admon, A., Kehat, I., Caspi, L.H., Gonen, H., Bercovich, B., Godzik, A., Jahandideh, S., Jaroszewski, L., Sommer, T., Kwon, Y.T., Guharoy, M., Tompa, P. and Ciechanover, A.
Proceedings of the National Academy of Sciences of the United States of America 113
(32): E4639-E4647.
9 August 2016
Relapse of NPM1-mutated AML with extramedullary manifestation 17 years after allogeneic hematopoietic stem cell transplantation.
Braune, J., Rieger, K., Blau, O., Keller, U., Bullinger, L. and Krönke, J.
Case Reports in Hematology 2022
: 3317936.
28 December 2022
TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck, F., Fischer, B., Witt, M., Muschhammer, J., Oelrich, J., da Costa Avelar, P.H., Tsoka, S., Bullinger, L., Seubert, E., Smit, D.J., Bokemeyer, C., Ackermann, C., Wellbrock, J., Haag, F. and Fiedler, W.
Journal for ImmunoTherapy of Cancer 10
(12): e004794.
22 December 2022
High-resolution experimental and computational profiling of tissue-specific known and novel miRNAs in Arabidopsis.
Breakfield, N.W., Corcoran, D.L., Petricka, J.J., Shen, J., Sae-Seaw, J., Rubio-Somoza, I., Weigel, D., Ohler, U. and Benfey, P.N.
Genome Research 22
(1): 163-176.
January 2012
Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.
Breit, T.M., Mol, E.J., Wolvers-Tettero, I.L., Ludwig, W.D., van Wering, E.R. and van Dongen, J.J.
Journal of Experimental Medicine 177
(4): 965-977.
1 April 1993
Optimization of synthetic molecular reporters for a mesenchymal glioblastoma transcriptional program by integer programming.
Breitenbach, T., Schmitt, M.J. and Dandekar, T.
Bioinformatics 38
(17): 4162-4171.
1 September 2022
Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production.
Breitfeld, D., Ohl, L., Kremmer, E., Ellwart, J., Sallusto, F., Lipp, M. and Foerster, R.
Journal of Experimental Medicine 192
(11): 1545-1551.
4 December 2000
M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
Breitkreuz-Korff, O., Tscheik, C., Del Vecchio, G., Dithmer, S., Walther, W., Orthmann, A., Wolburg, H., Haseloff, R.F., Schröder, L., Blasig, I.E. and Winkler, L.
Journal of Controlled Release 330
: 137-148.
10 August 2021
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Brembeck, F.H., Schwarz-Romond, T., Bakkers, J., Wilhelm, S., Hammerschmidt, M. and Birchmeier, W.
Genes & Development 18
(18): 2225-2230.
15 September 2004
BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H., Wiese, M., Zatula, N., Grigoryan, T., Dai, Y., Fritzmann, J. and Birchmeier, W.
Gastroenterology 141
(4): 1359-1370.
October 2011
A rapid bioinformatic method identifies novel genes with direct clinical relevance to colon cancer.
Brett, D., Kemmner, W., Koch, G., Roefzaad, C., Gross, S. and Schlag, P.M.
Oncogene 20
(33): 4581-4585.
27 July 2001
Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness.
Breun, M., Flock, K., Feldheim, J., Nattmann, A., Monoranu, C.M., Herrmann, P., Ernestus, R.I., Löhr, M., Hagemann, C. and Stein, U.
Cancers 15
(16): 4089.
14 August 2023
Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates.
Briesemeister, D., Friese, C., Isern, C.C., Dietz, E., Blankenstein, T., Thoene-Reineke, C. and Kammertoens, T.
Cytokine 60
(3): 626-633.
December 2012
Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis.
Briesemeister, D., Sommermeyer, D., Loddenkemper, C., Loew, R., Uckert, W., Blankenstein, T. and Kammertoens, T.
International Journal of Cancer 128
(2): 371-378.
15 January 2011
Mechanisms of targeting the MDM2-p53-FOXM1 axis in well-differentiated intestinal neuroendocrine tumors.
Briest, F., Grass, I., Sedding, D., Moebs, M., Christen, F., Benecke, J., Fuchs, K., Mende, S., Kaemmerer, D., Saenger, J., Kunze, A., Geisler, C., Freitag, H., Lewens, F., Worpenberg, L., Iwaszkiewicz, S., Siegmund, B., Walther, W., Hummel, M. and Grabowski, P.
Neuroendocrinology 107
(1): 1-23.
July 2018
Does the proteasome inhibitor bortezomib sensitize to DNA-damaging therapy in gastroenteropancreatic neuroendocrine neoplasms? - A preclinical assessment in vitro and in vivo.
Briest, F., Koziolek, E.J., Albrecht, J., Schmidt, F., Bernsen, M.R., Haeck, J., Kühl, A.A., Sedding, D., Hartung, T., Exner, S., Welzel, M., Fischer, C., Grötzinger, C., Brenner, W., Baum, R.P. and Grabowski, P.
Neoplasia 23
(1): 80-98.
January 2021
Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F., Noerenberg, D., Hennch, C., Yoshida, K., Hablesreiter, R., Nimo, J., Sasca, D., Kirchner, M., Mansouri, L., Inoue, Y., Wiegand, L., Staiger, A.M., Casadei, B., Korkolopoulou, P., Weiner, J., Lopez-Guillermo, A., Warth, A., Schneider, T., Nagy, Á., Klapper, W., Hummel, M., Kanellis, G., Anagnostopoulos, I., Mertins, P., Bullinger, L., Rosenquist, R., Vassilakopoulos, T.P., Ott, G., Ogawa, S. and Damm, F.
Leukemia 37
(11): 2237-2249.
November 2023
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.
Brinkmann, V., Foroutan, H., Sachs, M., Weidner, K.M. and Birchmeier, W.
Journal of Cell Biology 131
(6 Pt. 1): 1573-1586.
December 1995
Rap-specific GTPase activating protein follows an alternative mechanism.
Brinkmann, T., Daumke, O., Herbrand, U., Kühlmann, D., Stege, P., Ahmadian, M.R. and Wittinghofer, A.
Journal of Biological Chemistry 277
(15): 12525-31.
12 April 2002
NF-κB determines Paneth versus goblet cell fate decision in the small intestine.
Brischetto, C., Krieger, K., Klotz, C., Krahn, I., Kunz, S., Kolesnichenko, M., Mucka, P., Heuberger, J., Scheidereit, C. and Schmidt-Ullrich, R.
Development 148
(21): dev199683.
November 2021
MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors.
Brischwein, K., Schlereth, B., Guller, B., Steiger, C., Wolf, A., Lutterbuese, R., Offner, S., Locher, M., Urbig, T., Raum, T., Kleindienst, P., Wimberger, P., Kimmig, R., Fichtner, I., Kufer, P., Hofmeister, R., da Silva, A.J. and Baeuerle, P.A.
Molecular Immunology 43
(8): 1129-1143.
March 2006
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.
Brockmann, M., Poon, E., Berry, T., Carstensen, A., Deubzer, H.E., Rycak, L., Jamin, Y., Thway, K., Robinson, S.P., Roels, F., Witt, O., Fischer, M., Chesler, L. and Eilers, M.
Cancer Cell 24
(1): 75-89.
8 July 2013
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.
Brocks, D., Schmidt, C.R., Daskalakis, M., Jang, H.S., Shah, N.M., Li, D., Li, J., Zhang, B., Hou, Y., Laudato, S., Lipka, D.B., Schott, J., Bierhoff, H., Assenov, Y., Helf, M., Ressnerova, A., Islam, M.S., Lindroth, A.M., Haas, S., Essers, M., Imbusch, C.D., Brors, B., Oehme, I., Witt, O., Lübbert, M., Mallm, J.P., Rippe, K., Will, R., Weichenhan, D., Stoecklin, G., Gerhäuser, C., Oakes, C.C., Wang, T. and Plass, C.
Nature Genetics 49
(7): 1052-1060.
July 2017
Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line - cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.
Brockstedt, E., Rickers, A., Kostka, S., Laubersheimer, A., Doerken, B., Wittmann-Liebold, B., Bommert, K. and Otto, A.
Journal of Biological Chemistry 273
(43): 28057-28064.
23 October 1998
Single amino acid exchange in bacteriophage HK620 tailspike protein results in thousand-fold increase of its oligosaccharide affinity.
Broeker, N.K., Gohlke, U., Müller, J.J., Uetrecht, C., Heinemann, U., Seckler, R. and Barbirz, S.
Glycobiology 23
(1): 59-68.
January 2013
Time-resolved DNA release from an O-antigen specific Salmonella bacteriophage with a contractile tail.
Broeker, N.K., Roske, Y., Valleriani, A., Stephan, M.S., Andres, D., Koetz, J., Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 294
(31): 11751-11761.
2 August 2019
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, A.M., Vockentanz, L., Kharazi, S., Huska, M.R., Mancini, E., Scheller, M., Kuhl, C., Enns, A., Prinz, M., Jaenisch, R., Nerlov, C., Leutz, A., Andrade-Navarro, M.A., Jacobsen, S.E. and Rosenbauer, F.
Nature Genetics 41
(11): 1207-1215.
November 2009
Stat3 activation is required for cellular transformation by v-src.
Bromberg, J.F., Horvath, C.M., Besser, D., Lathem, W.W. and Darnell, J.E.
Molecular and Cellular Biology 18
(5): 2553-2558.
May 1998
Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy.
Brueckner, B., Rius, M., Rivera Markelova, M., Fichtner, I., Hals, P.A., Sandvold, M.L. and Lyko, F.
Molecular Cancer Therapeutics 9
(5): 1256-1264.
May 2010
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.
Bruedigam, C., Bagger, F.O., Heidel, F.H., Paine Kuhn, C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W.
Cell Stem Cell 15
(6): 775-90.
4 December 2014
Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia.
Bruedigam, C., Porter, A.H., Song, A., Vroeg In de Wei, G., Stoll, T., Straube, J., Cooper, L., Cheng, G., Kahl, V.F.S., Sobinoff, A.P., Ling, V.Y., Jebaraj, B.M.C., Janardhanan, Y., Haldar, R., Bray, L.J., Bullinger, L., Heidel, F.H., Kennedy, G.A., Hill, M.M., Pickett, H.A., Abdel-Wahab, O., Hartel, G. and Lane, S.W.
Nature Cancer 5
(1): 47-65.
January 2024
Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation.
Brunner, A.D., Thielert, M., Vasilopoulou, C., Ammar, C., Coscia, F., Mund, A., Hoerning, O.B., Bache, N., Apalategui, A., Lubeck, M., Richter, S., Fischer, D.S., Raether, O., Park, M.A., Meier, F., Theis, F.J. and Mann, M.
Molecular Systems Biology 18
(3): e10798.
1 March 2022
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses.
Brunner, T.M., Serve, S., Marx, A.F., Fadejeva, J., Saikali, P., Dzamukova, M., Durán-Hernández, N., Kommer, C., Heinrich, F., Durek, P., Heinz, G.A., Höfer, T., Mashreghi, M.F., Kühn, R., Pinschewer, D.D. and Löhning, M.
Nature Immunology 25
(2): 256-267.
February 2024
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann, J., Lorenz, C., Borchmann, S., Nishii, K., Wegner, J., Meder, L., Ostendorp, J., Ast, D.F., Heimsoeth, A., Nakasuka, T., Hirabae, A., Okawa, S., Dammert, M.A., Plenker, D., Klein, S., Lohneis, P., Gu, J., Godfrey, L.K., Forster, J., Trajkovic-Arsic, M., Zillinger, T., Haarmann, M., Quaas, A., Lennartz, S., Schmiel, M., D'Rozario, J., Thomas, E.S., Li, H., Schmitt, C.A., George, J., Thomas, R.K., von Karstedt, S., Hartmann, G., Büttner, R., Ullrich, R.T., Siveke, J.T., Ohashi, K., Schlee, M. and Sos, M.L.
Nature Communications 12
(1): 5505.
17 September 2021
Nivolumab and doxorubicin, vinblastine, and dacarbazine in early-stage unfavorable Hodgkin Lymphoma: final analysis of the randomized german Hodgkin study group phase II NIVAHL trial.
Bröckelmann, P.J., Bühnen, I., Meissner, J., Trautmann-Grill, K., Herhaus, P., Halbsguth, T.V., Schaub, V., Kerkhoff, A., Mathas, S., Bormann, M., Dickhut, A., Kaul, H., Fuchs, M., Kobe, C., Baues, C., Borchmann, P., Engert, A. and von Tresckow, B.
Journal of Clinical Oncology 41
(6): 1193-1199.
20 February 2023
Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial.
Bröckelmann, P.J., Goergen, H., Keller, U., Meissner, J., Ordemann, R., Halbsguth, T.V., Sasse, S., Sökler, M., Kerkhoff, A., Mathas, S., Hüttmann, A., Bormann, M., Zimmermann, A., Mettler, J., Fuchs, M., von Tresckow, B., Baues, C., Rosenwald, A., Klapper, W., Kobe, C., Borchmann, P. and Engert, A.
JAMA Oncology 6
(6): 872-880.
June 2020
Phase I trial of an allogeneic gene-modified tumor cell vaccine (RCC-26/CD80/IL-2) in patients with metastatic renal cell carcinoma.
Buchner, A., Pohla, H., Willimsky, G., Frankenberger, B., Frank, R., Baur-Melnyk, A., Siebels, M., Stief, C.G., Hofstetter, A., Kopp, J., Pezzutto, A., Blankenstein, T., Oberneder, R. and Schendel, D.J.
Human Gene Therapy 21
(3): 285-297.
March 2010
Systematic identification of A-to-I RNA editing in zebrafish development and adult organs.
Buchumenski, I., Holler, K., Appelbaum, L., Eisenberg, E., Junker, J.P. and Levanon, E.Y.
Nucleic Acids Research 49
(8): 4325-4337.
7 May 2021
6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group.
Buechner, T., Hiddemann, W., Berdel, W.E., Woermann, B., Schoch, C., Fonatsch, C., Loeffler, H., Haferlach, T., Ludwig, W.D., Maschmeyer, G., Staib, P., Aul, C., Grueneisen, A., Lengfelder, E., Frickhofen, N., Kern, W., Serve, H.L., Mesters, R.M., Sauerland, M.C. and Heinecke, A.
Journal of Clinical Oncology 21
: 4496-4504.
15 December 2003
The receptor tyrosine kinase p185HER2 is expressed on a subset of B-lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia.
Buehring, H.J., Sures, I., Jallal, B., Weiss, F.U., Busch, F.W., Ludwig, W.D., Handgretinger, R., Waller, H.D. and Ullrich, A.
Blood 86
(5): 1916-1923.
1 September 1995
Structural evidence of active site adaptability towards different sized substrates of aromatic amino acid aminotransferase from Psychrobacter sp. B6.
Bujacz, A., Rum, J., Rutkiewicz, M., Pietrzyk-Brzezinska, A.J. and Bujacz, G.
Materials 14
(12): 3351.
2 June 2021
PRAME-induced inhibition of retinoic acid receptor signaling-mediated differentiation - a possible target for ATRA response in AML without t(15;17).
Bullinger, L., Schlenk, R.F., Götz, M., Botzenhardt, U., Hofmann, S., Russ, A.C., Babiak, A., Zhang, L., Schneider, V., Döhner, K., Schmitt, M., Döhner, H. and Greiner, J.
Clinical Cancer Research 19
(9): 2562-71.
1 May 2013
RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer.
Bunse, M., Bendle, G.M., Linnemann, C., Bies, L., Schulz, S., Schumacher, T.N. and Uckert, W.
Molecular Therapy 22
(11): 1983-1991.
November 2014
Generation of redirected engineered human chimeric antigen receptor (CAR) T cells.
Bunse, M. and Höpken, U.E.
Methods in Molecular Biology 2521
(3): 67-83.
23 June 2022
CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells.
Bunse, M., Pfeilschifter, J., Bluhm, J., Zschummel, M., Joedicke, J.J., Wirges, A., Stark, H., Kretschmer, V., Chmielewski, M., Uckert, W., Abken, H., Westermann, J., Rehm, A. and Höpken, U.E.
Nature Communications 12
(1): 240.
11 January 2021
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Buonamici, S., Trimarchi, T., Ruocco, M.G., Reavie, L., Cathelin, S., Mar, B.G., Klinakis, A., Lukyanov, Y., Tseng, J.C., Sen, F., Gehrie, E., Li, M., Newcomb, E., Zavadil, J., Meruelo, D., Lipp, M., Ibrahim, S., Efstratiadis, A., Zagzag, D., Bromberg, J.S., Dustin, M.L. and Aifantis, I.
Nature 459
(7249): 1000-1004.
18 June 2009
Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Buonocore, F., Kuehnen, P., Suntharalingham, J.P., Del Valle, I., Digweed, M., Stachelscheid, H., Khajavi, N., Didi, M., Brady, A.F., Blankenstein, O., Procter, A.M., Dimitri, P., Wales, J.K.H., Ghirri, P., Knoebl, D., Strahm, B., Erlacher, M., Wlodarski, M.W., Chen, W., Kokai, G.K., Anderson, G., Morrogh, D., Moulding, D.A., McKee, S. A., Niemeyer, C.M., Grueters, A. and Achermann, J.C.
Journal of Clinical Investigation 127
(5): 1700-1713.
1 May 2017
Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.
Burek, M., Maddika, S., Burek, C.J., Daniel, P.T., Schulze-Osthoff, K. and Los, M.
Oncogene 25
: 2213-2222.
6 April 2006
Copy-number dosage regulates telomere maintenance and disease-associated pathways in neuroblastoma.
Burkert, M., Blanc, E., Thiessen, N., Weber, C., Toedling, J., Monti, R., Dombrowe, V.M., de Biase, M.S., Kaufmann, T.L., Haase, K., Waszak, S.M., Eggert, A., Beule, D., Schulte, J.H., Ohler, U. and Schwarz, R.F.
iScience 27
(10): 110918.
18 October 2024
The recurrent atypical e8a2 BCR::ABL1 transcript with insertion of an inverted 55 base pair ABL1 intron 1b sequence: a detailed molecular analysis.
Burmeister, T., Bullinger, L. and le Coutre, P.
Acta Haematologica 146
(5): 413-418.
October 2023
Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.
Burmeister, T., Gröger, D., Gökbuget, N., Spriewald, B., Starck, M., Elmaagacli, A., Hoelzer, D., Keller, U. and Schwartz, S.
Scientific Reports 13
(1): 15167.
13 September 2023
Circulating metastasis associated in colon cancer 1 transcripts in gastric cancer patient plasma as diagnostic and prognostic biomarker.
Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Stein, U.
World Journal of Gastroenterology 21
(1): 333-341.
7 January 2015
Integration der Hyperthermie in chirurgisch-onkologische Techniken [Integration of hyperthermia into surgical oncological techniques].
Burock, S. and Schlag, P.M.
Onkologe 16
(11): 1079-1085.
November 2010
Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial.
Burock, S., Daum, S., Keilholz, U., Neumann, K., Walther, W. and Stein, U.
BMC Cancer 18
(1): 297.
15 March 2018
Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes.
Burridge, P.W., Diecke, S., Matsa, E., Sharma, A., Wu, H. and Wu, J.C.
Methods in Molecular Biology 1353
: 119-130.
2016
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes.
Burster, T., Beck, A., Tolosa, E., Marin-Esteban, V., Roetzschke, O., Falk, K., Lautwein, A., Reich, M., Brandenburg, J., Schwarz, G., Wiendl, H., Melms, A., Lehmann, R., Stevanovic, S., Kalbacher, H. and Driessen, C.
Journal of Immunology 172
(9): 5495-5503.
1 January 2004
Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro.
Burster, T., Becker, A., Poeschel, S., Oren, A., Baechle, D., Reich, M., Roetzschke, O., Falk, K., Boehm, B.O., Youssef, S., Kalbacher, H., Overkleeft, H., Tolosa, E. and Driessen, C.
Immunology 121
(1): 82-93.
May 2007
Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions.
Burster, T., Marin-Esteban, V., Boehm, B.O., Dunn, S., Roetzschke, O., Falk, K., Weber, E., Verhelst, S.H., Kalbacher, H. and Driessen, C.
Biochemical Pharmacology 74
(10): 1514-1523.
15 November 2007
Isolation and long-term cultivation of mouse alveolar macrophages.
Busch, C. J.-L., Favret, J., Geirsdóttir, L., Molawi, K. and Sieweke, M.H.
Bio-protocol 9
(14)
20 July 2019
Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas.
Busch, J., Ralla, B., Jung, M., Wotschofsky, Z., Trujillo-Arribas, E., Schwabe, P., Kilic, E., Fendler, A. and Jung, K.
Journal of Experimental & Clinical Cancer Research 34
(1): 61.
14 June 2015
Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M., Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M., Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A., Scheidereit, C., Butter, C., Felix, S.B., Otto, O., Luft, F.C., Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12
(6): 1653-1668.
December 2021
Arabidopsis KCBP interacts with AIR9 but stays in the cortical division zone throughout mitosis via its MyTH4-FERM domain.
Buschmann, H., Dols, J., Kopischke, S., Pena, E.J., Andrade-Navarro, M.A., Heinlein, M., Szymanski, D.B., Zachgo, S., Doonan, J.H. and Lloyd, C.W.
Journal of Cell Science 28
(11): 2033-2046.
1 June 2015
In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance.
Buschow, C., Charo, J., Anders, K., Loddenkemper, C., Jukica, A., Alsamah, W., Perez, C., Willimsky, G. and Blankenstein, T.
Journal of Immunology 184
(6): 2930-2938.
15 March 2010
Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA interdisciplinary expert consensus.
Buske, C., Dreyling, M., Alvarez-Larrán, A., Apperley, J., Arcaini, L., Besson, C., Bullinger, L., Corradini, P., Della Porta, M.G., Dimopoulos, M., D’Sa, S., Eich, H.T., Foà, R., Ghia, P., Gomes da Silva, M., Gribben, J., Hajek, R., Harrison, C., Heuser, M., Kiesewetter, B., Kiladjian, J.J., Kröger, N., Moreau, P., Passweg, J.R., Peyvandi, F., Rea, D., Ribera, J.M., Robak, T., San-Miguel, J.F., Santini, V., Sanz, G., Sonneveld, P., von Lilienfeld-Toal, M., Wendtner, C., Pentheroudakis, G. and Passamonti, F.
ESMO Open 7
(2): 100403.
April 2022
Sensitivity of tumor cells to proteasome inhibitors is associated with expression levels and composition of proteasome subunits.
Busse, A., Kraus, M., Na, I.K., Rietz, A., Scheibenbogen, C., Driessen, C., Blau, I.W., Thiel, E. and Keilholz, U.
Cancer 112
(3): 659-670.
1 February 2008
Expression of protein complexes using multiple E. coli protein co-expression systems: a benchmarking study.
Busso, D., Peleg, Y., Heidebrecht, T., Romier, C., Jacobovitch, Y., Dantes, A., Salim, L., Troesch, E., Schuetz, A., Heinemann, U., Folkers, G.E., Geerlof, A., Wilmanns, M., Polewacz, A., Quedenau, C., Büssow, K., Adamson, R., Blagova, E., Walton, J., Cartwright, J.L., Bird, L.E., Owens, R.J., Berrow, N.S., Wilson, K.S., Sussman, J.L., Perrakis, A. and Celie, P.H.
Journal of Structural Biology 175
(2): 159-170.
August 2011
Detection, isolation and partial characterization of an immunostimulating glycoprotein from Rhodococcus fascians.
Butschak, G., Karsten, U., Schelhaas, U., Ott, H., Emmendoerffer, A., Niemeyer, B., Helmholz, H. and Goletz, S.
International Immunopharmacology 6
(9): 1441-1450.
September 2006
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Bywater, M.J., Poortinga, G., Sanij, E., Hein, N., Peck, A., Cullinane, C., Wall, M., Cluse, L., Drygin, D., Anderes, K., Huser, N., Proffitt, C., Bliesath, J., Haddach, M., Schwaebe, M.K., Ryckman, D.M., Rice, W.G., Schmitt, C., Lowe, S.W., Johnstone, R.W., Pearson, R.B., McArthur, G.A. and Hannan, R.D.
Cancer Cell 22
(1): 51-65.
10 July 2012
Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I., Jaeschke, L., Nimptsch, K., Janke, J., Herrmann, P., Kobelt, D., Kielstein, H., Pischon, T. and Stein, U.
International Journal of Oncology 60
(2): 17.
February 2022
The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.
Bégay, V., Baumeier, C., Zimmermann, K., Heuser, A. and Leutz, A.
Scientific Reports 8
(1): 8417.
30 May 2018
Essential requirement of CCAAT/enhancer binding proteins in embryogenesis.
Bégay, V., Smink, J. and Leutz, A.
Molecular and Cellular Biology 24
(22): 9744-9751.
1 November 2004
Deregulation of the endogenous C/EBPβ LIP isoform predisposes to tumorigenesis.
Bégay, V., Smink, J.J., Loddenkemper, C., Zimmermann, K., Rudolph, C., Scheller, M., Steinemann, D., Leser, U., Schlegelberger, B., Stein, H. and Leutz, A.
Journal of Molecular Medicine 93
(1): 39-49.
January 2015
Analysis of the CDK4/6 cell cycle pathway in leiomyosarcomas as a potential target for inhibition by palbociclib.
Böhm, M.J., Marienfeld, R., Jäger, D., Mellert, K., von Witzleben, A., Brüderlein, S., Wittau, M., von Baer, A., Schultheiss, M., Mayer-Steinacker, R., Rücker, F.G., Möller, P., Bullinger, L. and Barth, T.F.E.
Sarcoma 2019
: 3914232.
21 January 2019
NF-κB signaling in tanycytes mediates inflammation-induced anorexia.
Böttcher, M., Müller-Fielitz, H., Sundaram, S.M., Gallet, S., Neve, V., Shionoya, K., Zager, A., Quan, N., Liu, X., Schmidt-Ullrich, R., Haenold, R., Wenzel, J., Blomqvist, A., Engblom, D., Prevot, V. and Schwaninger, M.
Molecular Metabolism 39
: 101022.
September 2020
Inferior outcomes of EU versus US patients treated with CD19 CAR-T for relapsed/refractory large B-cell lymphoma: association with differences in tumor burden, systemic inflammation, bridging therapy utilization, and CAR-T product use.
Bücklein, V., Perez, A., Rejeski, K., Iacoboni, G., Jurinovic, V., Holtick, U., Penack, O., Kharboutli, S., Blumenberg, V., Ackermann, J., Frölich, L., Johnson, G., Patel, K., Arciola, B., Mhaskar, R., Wood, A., Schmidt, C., Albanyan, O., Gödel, P., Hoster, E., Bullinger, L., Mackensen, A., Locke, F., von Bergwelt, M., Barba, P., Subklewe, M. and Jain, M.D.
HemaSphere 7
(8): e907.
August 2023
Gene therapy "Made in Germany": a historical perspective, analysis of the status quo, and recommendations for action by the German Society for Gene Therapy.
Büning, H., Fehse, B., Ivics, Z., Kochanek, S., Koehl, U., Kupatt, C., Mussolino, C., Nettelbeck, D.M., Schambach, A., Uckert, W., Wagner, E. and Cathomen, T.
Human Gene Therapy 32
(19-20): 987-996.
18 October 2021
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Cabezas-Wallscheid, N., Klimmeck, D., Hansson, J., Lipka, D.B., Reyes, A., Wang, Q., Weichenhan, D., Lier, A., von Paleske, L., Renders, S., Wünsche, P., Zeisberger, P., Brocks, D., Gu, L., Herrmann, C., Haas, S., Essers, M.A.G., Brors, B., Eils, R., Huber, W., Milsom, M.D., Plass, C., Krijgsveld, J. and Trumpp, A.
Cell Stem Cell 15
(4): 507-522.
2 October 2014
Single cell biology - a Keystone Symposia report.
Cable, J., Elowitz, M.B., Domingos, A.I., Habib, N., Itzkovitz, S., Hamidzada, H., Balzer, M.S., Yanai, I., Liberali, P., Whited, J., Streets, A., Cai, L., Stergachis, A.B., Hong, C.K.Y., Keren, L., Guilliams, M., Alon, U., Shalek, A.K., Hamel, R., Pfau, S.J., Raj, A., Quake, S.R., Zhang, N.R., Fan, J., Trapnell, C., Wang, B., Greenwald, N.F., Vento-Tormo, R., Santos, S.D.M., Spencer, S.L., Garcia, H.G., Arekatla, G., Gaiti, F., Arbel-Goren, R., Rulands, S., Junker, J.P., Klein, A.M., Morris, S.A., Murray, J.I., Galloway, K.E., Ratz, M. and Romeike, M.
Annals of the New York Academy of Sciences 1506
(1): 74-97.
December 2021
Cancer stem cells: advances in biology and clinical translation -- a Keystone Symposia report.
Cable, J., Pei, D., Reid, L.M., Wang, X.W., Bhatia, S., Karras, P., Melenhorst, J.J., Grompe, M., Lathia, J.D., Song, E., Kuo, C.J., Zhang, N., White, R.M., Ma, S.K., Ma, L., Chin, Y.R., Shen, M.M., Ng, I.O.L., Kaestner, K.H., Zhou, L., Sikandar, S., Schmitt, C.A., Guo, W., Wong, C.C.L., Ji, J., Tang, D.G., Dubrovska, A., Yang, C., Wiedemeyer, W.R. and Weissman, I.L.
Annals of the New York Academy of Sciences 1506
(1): 142–163.
December 2021
Human and mouse essentiality screens as a resource for disease gene discovery.
Cacheiro, P., Muñoz-Fuentes, V., Murray, S.A., Dickinson, M.E., Bucan, M., Nutter, L.M.J., Peterson, K.A., Haselimashhadi, H., Flenniken, A.M., Morgan, H., Westerberg, H., Konopka, T., Hsu, C.W., Christiansen, A., Lanza, D.G., Beaudet, A.L., Heaney, J.D., Fuchs, H., Gailus-Durner, V., Sorg, T., Prochazka, J., Novosadova, V., Lelliott, C.J., Wardle-Jones, H., Wells, S., Teboul, L., Cater, H., Stewart, M., Hough, T., Wurst, W., Sedlacek, R., Adams, D.J., Seavitt, J.R., Tocchini-Valentini, G., Mammano, F., Braun, R.E., McKerlie, C., Herault, Y., de Angelis, M.H., Mallon, A.M., Lloyd, K.C.K., Brown, S.D.M., Parkinson, H., Meehan, T.F. and Smedley, D.
Nature Communications 11
(1): 655.
31 January 2020
Sentinel node biopsy for the individualization of surgical strategy for cure of early-stage colon cancer.
Cahill, R.A., Bembenek, A., Sirop, S., Waterhouse, D.F., Schneider, W., Leroy, J., Wiese, D., Beutler, T., Bilchik, A., Saha, S. and Schlag, P.M.
Annals of Surgical Oncology 16
(8): 2170-2180.
August 2009
Genomic basis for RNA alterations in cancer.
Calabrese, C., Davidson, N.R., Demircioğlu, D., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., Soulette, C.M., Urban, L., Greger, L., Li, S., Liu, D., Perry, M.D., Xiang, Q., Zhang, F., Zhang, J., Bailey, P., Erkek, S., Hoadley, K.A., Hou, Y., Huska, M.R., Kilpinen, H., Korbel, J.O., Marin, M.G., Markowski, J., Nandi, T., Pan-Hammarström, Q., Pedamallu, C.S., Siebert, R., Stark, S.G., Su, H., Tan, P., Waszak, S.M., Yung, C., Zhu, S., Awadalla, P., Creighton, C.J., Meyerson, M., Ouellette, B.F.F., Wu, K., Yang, H., Brazma, A., Brooks, A.N., Göke, J., Rätsch, G., Schwarz, R.F., Stegle, O. and Zhang, Z.
Nature 578
(7793): 129-136.
6 February 2020
Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma.
Calado, D.P., Zhang, B., Srinivasan, L., Sasaki, Y., Seagal, J., Unitt, C., Rodig, S., Kutok, J., Tarakhovsky, A., Schmidt-Supprian, M. and Rajewsky, K.
Cancer Cell 18
(6): 580-589.
14 December 2010
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P., Sasaki, Y., Godinho, S.A., Pellerin, A., Köchert, K., Sleckman, B.P., de Alboran, I.M., Janz, M., Rodig, S. and Rajewsky, K.
Nature Immunology 13
(11): 1092-1100.
November 2012
Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly (ethylene glycol) shell.
Calderon, M., Welker, P., Licha, K., Fichtner, I., Graeser, R., Haag, R. and Kratz, F.
Journal of Controlled Release 151
(3): 295-301.
10 May 2011
Translational control of SCL-isoform expression in hematopoietic lineage choice.
Calkhoven, C.F., Mueller, C., Martin, R., Krosl, G., Hoang, T. and Leutz, A.
Genes & Development 17
(8): 959-964.
15 April 2003
53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Callen, E., Di Virgilio, M., Kruhlak, M.J., Nieto-Soler, M., Wong, N., Chen, H.T., Faryabi, R.B., Polato, F., Santos, M., Starnes, L.M., Wesemann, D.R., Lee, J.E., Tubbs, A., Sleckman, B.P., Daniel, J.A., Ge, K., Alt, F.W., Fernandez-Capetillo, O., Nussenzweig, M.C. and Nussenzweig, A.
Cell 153
(6): 1266-1280.
6 June 2013
Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Callen, E., Jankovic, M., Wong, N., Zha, S., Chen, H.T., Difilippantonio, S., Di Virgilio, M., Heidkamp, G., Alt, F.W., Nussenzweig, A. and Nussenzweig, M.
Molecular Cell 34
(3): 285-297.
15 May 2009
Detecting actively translated open reading frames in ribosome profiling data.
Calviello, L., Mukherjee, N., Wyler, E., Zauber, H., Hirsekorn, A., Selbach, M., Landthaler, M., Obermayer, B. and Ohler, U.
Nature Methods 13
(2): 165-170.
February 2016
Quantification of translation uncovers the functions of the alternative transcriptome.
Calviello, L., Hirsekorn, A. and Ohler, U.
Nature Structural & Molecular Biology 27
(8): 717-725.
August 2020
DDX3 depletion represses translation of mRNAs with complex 5' UTRs.
Calviello, L., Venkataramanan, S., Rogowski, K.J., Wyler, E., Wilkins, K., Tejura, M., Thai, B., Krol, J., Filipowicz, W., Landthaler, M. and Floor, S.N.
Nucleic Acids Research 49
(9): 5336-5350.
May 2021
In vitro and in vivo stability of the epsilon2zeta2 protein complex of the broad host-range Streptococcus pyogenes pSM19035 addiction system.
Camacho, A.G., Misselwitz, R., Behlke, J., Ayora, S., Welfle, K., Meinhart, A., Lara, B., Saenger, W., Welfle, H. and Alonso, J.C.
Biological Chemistry 383
(11): 1701-1713.
November 2002
Expression of CD175 (Tn), CD175s (sialosyl-Tn) and CD176 (Thomsen-Friedenreich antigen) on malignant human hematopoietic cells.
Cao, Y., Merling, A., Karsten, U., Goletz, S., Punzel, M., Kraft, R., Butschak, G. and Schwartz-Albiez, R.
International Journal of Cancer 123
(1): 89-99.
1 July 2008
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish.
Cardeira-da-Silva, J., Wang, Q., Sagvekar, P., Mintcheva, J., Latting, S., Günther, S., Ramadass, R., Yekelchyk, M., Preussner, J., Looso, M., Junker, J.P. and Stainier, D.Y.R.
Nature Communications 15
(1): 3637.
29 April 2024
Differences in cell-type-specific responses to angiotensin II explain cardiac remodeling differences in C57BL/6 mouse substrains.
Cardin, S., Scott-Boyer, M.P., Praktiknjo, S., Jeidane, S., Picard, S., Reudelhuber, T.L. and Deschepper, C.F.
Hypertension 64
(5): 1040-1046.
November 2014
Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.
Carley, L.N., Mojica, J.P., Wang, B., Chen, C.Y., Lin, Y.P., Prasad, K.V.S.K, Chan, E., Hsu, C.W., Keith, R., Nuñez, C.L., Olson-Manning, C.F., Rushworth, C.A., Wagner, M.R., Wang, J., Yeh, P.M., Reichelt, M., Ghattas, K., Gershenzon, J., Lee, C.R. and Mitchell-Olds, T.
Nature Ecology & Evolution 5
: 1135-1144.
August 2021
The spatio-temporal pattern of testis organogenesis in mammals - insights from the mole.
Carmona, F.D., Lupianez, D.G., Martin, J.E., Burgos, M., Jimenez, R. and Zurita, F.
International Journal of Developmental Biology 53
(7): 1035-1044.
2009
SOX9 is not required for the cellular events of testicular organogenesis in XX mole ovotestes.
Carmona, F.D., Lupianez, D.G., Real, F.M., Burgos, M., Zurita, F. and Jimenez, R.
Journal of Experimental Zoology Part B : Molecular and Developmental Evolution 312
(7): 734-748.
15 November 2009
Proteomic signatures improve risk prediction for common and rare diseases.
Carrasco-Zanini, J., Pietzner, M., Davitte, J., Surendran, P., Croteau-Chonka, D.C., Robins, C., Torralbo, A., Tomlinson, C., Grünschläger, F., Fitzpatrick, N., Ytsma, C., Kanno, T., Gade, S., Freitag, D., Ziebell, F., Haas, S., Denaxas, S., Betts, J.C., Wareham, N.J., Hemingway, H., Scott, R.A. and Langenberg, C.
Nature Medicine 30
(9): 2489-2498.
September 2024
Single-cell lineage tracing approaches in hematology research: technical considerations.
Carrelha, J., Lin, D.S., Rodriguez-Fraticelli, A.E., Luis, T.C., Wilkinson, A.C., Cabezas-Wallscheid, N., Tremblay, C.S. and Haas, S.
Experimental Hematology 89
: 26-36.
September 2020
The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity.
Carriquí-Madroñal, B., Sheldon, J., Duven, M., Stegmann, C., Cirksena, K., Wyler, E., Zapatero-Belinchón, F.J., Vondran, F.W.R. and Gerold, G.
PLoS Pathogens 19
(11): e1011759.
15 November 2023
The alpha4beta1 and alpha5beta1 integrins mediate engraftment of granulocyte-colony-stimulating factor-mobilized human hematopoietic progenitor cells.
Carstanjen, D., Gross, A., Kosova, N., Fichtner, I. and Salama, A.
Transfusion 45
: 1192-1200.
1 July 2005
Detection of cell-free DNA in bronchial lavage fluid supernatants of patients with lung cancer.
Carstensen, T., Schmidt, B., Engel, E., Jandrig, B., Witt, C. and Fleischhacker, M.
Annals of the New York Academy of Sciences 1022
: 202-210.
1 June 2004
Enhanced properties of a benzimidazole benzylpyrazole lysine demethylase inhibitor: mechanism-of-action, binding site analysis, and activity in cellular models of prostate cancer.
Carter, D.M., Specker, E., Malecki, P.H., Przygodda, J., Dudaniec, K., Weiss, M.S., Heinemann, U., Nazaré, M. and Gohlke, U.
Journal of Medicinal Chemistry 64
(19): 14266-14282.
14 October 2021
Identification of a novel benzimidazole pyrazolone scaffold that inhibits KDM4 lysine demethylases and reduces proliferation of prostate cancer cells.
Carter, D.M., Specker, E., Przygodda, J., Neuenschwander, M., von Kries, J.P., Heinemann, U., Nazaré, M. and Gohlke, U.
SLAS Discovery 22
(7): 801-812.
1 August 2017
SRRM2 splicing factor modulates cell fate in early development.
Carvalho, S., Zea-Redondo, L., Tang, T.C.C., Stachel-Braum, P., Miller, D., Caldas, P., Kukalev, A., Diecke, S., Grosswendt, S., Grosso, A.R. and Pombo, A.
Biology Open 13
(4): bio060415.
April 2024
A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression.
Casado-Medrano, V., Barrio-Real, L., García-Rostán, G., Baumann, M., Rocks, O. and Caloca, M.J.
Oncotarget 7
(19): 28301-28319.
10 May 2016
Dynamo: a flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments.
Castaño-Díez, D., Kudryashev, M., Arheit, M. and Stahlberg, H.
Journal of Structural Biology 178
(2): 139-151.
May 2012
Dynamo Catalogue: geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms.
Castaño-Díez, D., Kudryashev, M. and Stahlberg, H.
Journal of Structural Biology 197
(2): 135-144.
February 2017
Management of busulfan-induced lung injury in pediatric patients with high-risk neuroblastoma.
Castelli, S., Thorwarth, A., van Schewick, C., Wendt, A., Astrahantseff, K., Szymansky, A., Lodrini, M., Veldhoen, S., Gratopp, A., Mall, M.A., Eggert, A. and Deubzer, H.E.
Journal of Clinical Medicine 13
(19): 5995.
8 October 2024
In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine.
Cayeux, S., Bukarica, B., Buschow, C., Charo, J., Bunse, M., Doerken, B. and Blankenstein, T.
Gene Therapy 14
(20): 1481-1491.
October 2007
The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription.
Cecere, G., Hoersch, S., Jensen, M.B., Dixit, S. and Grishok, A.
Molecular Cell 50
(6): 894-907.
27 June 2013
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N., Naumann, H., Ruzittu, S., Mah, N., Pongrac, I.M., Cozzitorto, C., Hommel, A., Andrade-Navarro, M.A., Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8
: 14127.
13 February 2017
Building a Healthcare Alliance for Resourceful Medicine Offensive Against Neoplasms in hematologY added value framework for hematologic malignancies: a comparative analysis of existing tools.
Cerisoli, F., Ali, F., Bereczky, T., Bolaños, N., Bullinger, L., Dhanasiri, S., Gallagher, J., Pérez, S.G., Geissler, J., Guillevic, Y., Harrison, K., Naoum, A., Portulano, C., Rodríguez Vicente, A.E., Schulze-Rath, R., Gómez, G.Y., Sanz, G. and Hernández Rivas, J.M.
Value in Health 25
(10): 1760-1767.
October 2022
Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.
Cerrone, M., Noorman, M., Lin, X., Chkourko, H., Liang, F.X., van der Nagel, R., Hund, T., Birchmeier, W., Mohler, P., van Veen, T.A., van Rijen, H.V. and Delmar, M.
Cardiovascular Research 95
(4): 460-468.
1 September 2012
Compound-SNE: comparative alignment of t-SNEs for multiple single-cell omics data visualization.
Cess, C.G. and Haghverdi, L.
Bioinformatics 40
(7): btae471.
July 2024
Multi-platform discovery of haplotype-resolved structural variation in human genomes.
Chaisson, M.J.P., Sanders, A.D., Zhao, X., Malhotra, A., Porubsky, D., Rausch, T., Gardner, E.J., Rodriguez, O.L., Guo, L., Collins, R.L., Fan, X., Wen, J., Handsaker, R.E., Fairley, S., Kronenberg, Z.N., Kong, X., Hormozdiari, F., Lee, D., Wenger, A.M., Hastie, A.R., Antaki, D., Anantharaman, T., Audano, P.A., Brand, H., Cantsilieris, S., Cao, H., Cerveira, E., Chen, C., Chen, X., Chin, C.S., Chong, Z., Chuang, N.T., Lambert, C.C., Church, D.M., Clarke, L., Farrell, A., Flores, J., Galeev, T., Gorkin, D.U., Gujral, M., Guryev, V., Heaton, W.H., Korlach, J., Kumar, S., Kwon, J.Y., Lam, E.T., Lee, J.E., Lee, J., Lee, W.P., Lee, S.P., Li, S., Marks, P., Viaud-Martinez, K., Meiers, S., Munson, K.M., Navarro, F.C.P., Nelson, B.J., Nodzak, C., Noor, A., Kyriazopoulou-Panagiotopoulou, S., Pang, A.W.C., Qiu, Y., Rosanio, G., Ryan, M., Stütz, A., Spierings, D.C.J., Ward, A., Welch, A.E., Xiao, M., Xu, W., Zhang, C., Zhu, Q., Zheng-Bradley, X., Lowy, E., Yakneen, S., McCarroll, S., Jun, G., Ding, L., Koh, C.L., Ren, B., Flicek, P., Chen, K., Gerstein, M.B., Kwok, P.Y., Lansdorp, P.M., Marth, G.T., Sebat, J., Shi, X., Bashir, A., Ye, K., Devine, S.E., Talkowski, M.E., Mills, R.E., Marschall, T., Korbel, J.O., Eichler, E.E. and Lee, C.
Nature Communications 10
(1): 1784.
16 April 2019
Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach.
Chakrabarti, P.P., Daumke, O., Suveyzdis, Y., Koetting, C., Gerwert, K. and Wittinghofer, A.
Journal of Molecular Biology 367
(4): 983-95.
6 April 2007
Comparing agent‐based delivery of DNA and PNA forced intercalation (FIT) probes for multicolor mRNA imaging.
Chamiolo, J., Fang, G.M., Hövelmann, F., Friedrich, D., Knoll, A., Loewer, A. and Seitz, O.
ChemBioChem 20
(4): 595-604.
15 February 2019
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R., Conrad, T., Stöber, M.C., Xu, R., Giurgiu, M., Rodriguez-Fos, E., Kasack, K., Brückner, L., van Leen, E., Helmsauer, K., Dorado Garcia, H., Stefanova, M.E., Hung, K.L., Bei, Y., Schmelz, K., Lodrini, M., Mundlos, S., Chang, H.Y., Deubzer, H.E., Sauer, S., Eggert, A., Schulte, J.H., Schwarz, R.F., Haase, K., Koche, R.P. and Henssen, A.G.
Nature Genetics 55
(5): 880-890.
May 2023
Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
Chan, G., Cheung, L.S., Yang, W., Milyavsky, M., Sanders, A.D., Gu, S., Hong, W.X., Liu, A.X., Wang, X., Barbara, M., Sharma, T., Gavin, J., Kutok, J.L., Iscove, N.N., Shannon, K.M., Dick, J.E., Neel, B.G. and Braun, B.S.
Blood 117
(16): 4253-4261.
21 April 2011
Molecular recording of mammalian embryogenesis.
Chan, M.M., Smith, Z.D., Grosswendt, S., Kretzmer, H., Norman, T.M., Adamson, B., Jost, M., Quinn, J.J., Yang, D., Jones, M.G., Khodaverdian, A., Yosef, N., Meissner, A. and Weissman, J.S.
Nature 570
(7759): 77-82.
6 June 2019
Bax-dependent regulation of Bak by voltage-dependent anion channel 2.
Chandra, D., Choy, G., Daniel, P.T. and Tang, D.G.
Journal of Biological Chemistry 280
: 19051-19061.
1 January 2005
Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death.
Chandra, D., Choy, G., Deng, X., Bhatia, B., Daniel, P. and Tang, D.G.
Molecular and Cellular Biology 24
: 6592-6607.
1 January 2004
Determining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging.
Chang, S.Y.S., Dijkman, P.M., Wiessing, S.A. and Kudryashev, M.
Scientific Reports 13
: 11523.
17 July 2023
Visualizing the dynamic of adoptively transferred T cells during the rejection of large established tumors.
Charo, J., Perez, C., Buschow, C., Jukica, A., Czeh, M. and Blankenstein, T.
European Journal of Immunology 41
(11): 3187-3197.
November 2011
STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
Chatterjee, M., Jain, S., Stuehmer, T., Andrulis, M., Ungethuem, U., Kuban, R.J., Lorentz, H., Bommert, K., Topp, M., Kramer, D., Mueller-Hermelink, H. K., Einsele, H., Greiner, A. and Bargou, R.C.
Blood 109
(2): 720-728.
15 January 2007
The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma.
Chatterjee, M., Rancso, C., Stuehmer, T., Eckstein, N., Andrulis, M., Gerecke, C., Lorentz, H., Royer, H.D. and Bargou, R.C.
Blood 111
(7): 3714-3722.
1 April 2008
Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M., Stuehmer, T., Herrmann, P., Bommert, K., Doerken, B. and Bargou, R.C.
Blood 104
(12): 3712-3721.
1 January 2004
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Chee, J.M., Lanoue, L., Clary, D., Higgins, K., Bower, L., Flenniken, A., Guo, R., Adams, D.J., Bosch, F., Braun, R.E., Brown, S.D.M., Chin, H.J.G., Dickinson, M.E., Hsu, C.W., Dobbie, M., Gao, X., Galande, S., Grobler, A., Heaney, J.D., Herault, Y., de Angelis, M.H., Mammano, F., Nutter, L.M.J, Parkinson, H., Qin, C., Shiroishi, T., Sedlacek, R., Seong, J.K., Xu, Y., Brooks, B., McKerlie, C., Lloyd, K.C.K., Westerberg, H. and Moshiri, A.
BMC Biology 21
(1): 22.
3 February 2023
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
Chemi, F., Rothwell, D.G., McGranahan, N., Gulati, S., Abbosh, C., Pearce, S.P., Zhou, C., Wilson, G.A., Jamal-Hanjani, M., Birkbak, N., Pierce, J., Kim, C.S., Ferdous, S., Burt, D.J., Slane-Tan, D., Gomes, F., Moore, D., Shah, R., Al Bakir, M., Hiley, C., Veeriah, S., Summers, Y., Crosbie, P., Ward, S., Mesquita, B., Dynowski, M., Biswas, D., Tugwood, J., Blackhall, F., Miller, C., Hackshaw, A., Brady, G., Swanton, C. and Dive, C.
Nature Medicine 25
(10): 1534-1539.
October 2019
The c-Myb functions as a downstream target of PDGF-mediated survival signal in vascular smooth muscle cells.
Chen, Y., Xu, H., Liu, J., Zhang, C., Leutz, A. and Mo, X.
Biochemical and Biophysical Research Communications 360
(2): 433-436.
24 August 2007
Structure of RyR1 in native membranes.
Chen, W. and Kudryashev, M.
EMBO Reports 21
(5): e49891.
6 May 2020
LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression.
Chen, W., Wang, F., Yu, X., Qi, J., Dong, H., Cui, B., Zhang, Q., Wu, Y., An, J., Ni, N., Liu, C., Han, Y., Zhang, S., Schmitt, C.A., Deng, J., Yu, Y. and Du, J.
Oncogene 43
(18): 1328-1340.
2 May 2024
Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X., Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214
(11): 3417-3433.
6 November 2017
Identification of 2-[4-[(4-methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers.
Cheng, X., Dimou, E., Alborzinia, H., Wenke, F., Goehring, A., Reuter, S., Mah, N., Fuchs, H., Andrade-Navarro, M.A., Adjaye, J., Gul, S., Harms, C., Utikal, J., Klipp, E., Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58
(12): 4976-4983.
25 June 2015
Ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4.
Cheng, X., Yoshida, H., Raoofi, D., Saleh, S., Alborzinia, H., Wenke, F., Goehring, A., Reuter, S., Mah, N., Fuchs, H.R., Andrade-Navarro, M.A., Adjaye, J., Gul, S., Utikal, J., Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58
(1): 5742-5750.
13 August 2015
Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.
Chevelkov, V., Faelber, K., Diehl, A., Heinemann, U., Oschkinat, H. and Reif, B.
Journal of Biomolecular NMR 31
(4): 295-310.
1 January 2005
Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R., Sternjak, A., Wend, P., Momma, S., Campos, B., Herrmann, I.M., Graf, D., Mitsiadis, T., Herold-Mende, C., Besser, D., Synowitz, M., Kettenmann, H. and Glass, R.
Brain 133
(Pt 7): 1961-1972.
July 2010
Immediate effects of reversible HTLV-I tax function: T-cell activation and apoptosis.
Chlichlia, K., Moldenhauer, G., Daniel, P.T., Busslinger, M., Gazzalo, L., Schirrmacher, V. and Khazaie, K.
Oncogene 10
(2): 269-277.
19 January 1995
c-Met is essential for wound healing in the skin.
Chmielowiec, J., Borowiak, M., Morkel, M., Stradal, T., Munz, B., Werner, S., Wehland, J., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177
(1): 151-162.
9 April 2007
miR-23~27~24 clusters control effector T cell differentiation and function.
Cho, S., Wu, C.J., Yasuda, T., Cruz, L.O., Khan, A.A., Lin, L.L., Nguyen, D.T., Miller, M., Lee, H.M., Kuo, M.L., Broide, D.H., Rajewsky, K., Rudensky, A.Y. and Lu, L.F.
Journal of Experimental Medicine 213
(2): 235-249.
8 February 2016
Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
Choi, I.K., Wang, Z., Ke, Q., Hong, M., Qian, Y., Zhao, X., Liu, Y., Kim, H.J., Ritz, J., Cantor, H., Rajewsky, K., Wucherpfennig, K.W. and Zhang, B.
Proceedings of the National Academy of Sciences of the United States of America 115
(4): E686-E695.
January 2018
Endothelial NF-κB blockade abrogates ANCA-induced GN.
Choi, M., Schreiber, A., Eulenberg-Gustavus, C., Scheidereit, C., Kamps, J. and Kettritz, R.
Journal of the American Society of Nephrology 28
(11): 3191-3204.
November 2017
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chong, C., Müller, M., Pak, H.S., Harnett, D., Huber, F., Grun, D., Leleu, M., Auger, A., Arnaud, M., Stevenson, B.J., Michaux, J., Bilic, I., Hirsekorn, A., Calviello, L., Simó-Riudalbas, L., Planet, E., Lubiński, J., Bryśkiewicz, M., Wiznerowicz, M., Xenarios, I., Zhang, L., Trono, D., Harari, A., Ohler, U., Coukos, G. and Bassani-Sternberg, M.
Nature Communications 11
(1): 1293.
10 March 2020
Development and validation of a three dimensional ultrasound based navigation system for tumor resection.
Chopra, S.S., Huenerbein, M., Eulenstein, S., Lange, T., Schlag, P.M. and Beller, S.
European Journal of Surgical Oncology 34
(4): 456-461.
April 2008
Rituximab in the management of post-transplantation lymphoproliferative disorder after solid organ transplantation: proceed with caution.
Choquet, S., Oertel, S., Leblond, V., Riess, H., Varoqueaux, N., Doerken, B. and Trappe, R.
Annals of Hematology 86
(8): 599-607.
August 2007
Structure of the active GGEEF domain of a diguanylate cyclase from Vibrio cholerae.
Chouhan, O.P., Roske, Y., Heinemann, U. and Biswas, S.
Biochemical and Biophysical Research Communications 523
(2): 287-292.
5 March 2020
Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F., Hablesreiter, R., Hoyer, K., Hennch, C., Maluck-Böttcher, A., Segler, A., Madadi, A., Frick, M., Bullinger, L., Briest, F. and Damm, F.
Leukemia 36
(4): 1102-1110.
April 2022
Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
Christen, F., Hoyer, K., Yoshida, K., Hou, H.A., Waldhueter, N., Heuser, M., Hills, R.K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W.C., Blau, I.W., Tang, J.L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Löwenberg, B., Linch, D.C., Bullinger, L., Valk, P.J.M., Tien, H.F., Gale, R.E., Ogawa, S. and Damm, F.
Blood 133
(10): 1140-1151.
7 March 2019
CRISPR/Cas9-mediated in vitro mutagenesis in GC-like B cells.
Chu, V.T., Graf, R. and Rajewsky, K.
Methods in Molecular Biology 1623
: 135-145.
2017
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T., Graf, R., Wirtz, T., Weber, T., Favret, J., Li, X., Petsch, K., Tran, N.T., Sieweke, M.H., Berek, C., Kühn, R. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113
(44): 12514-12519.
1 November 2016
Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.
Chu, V.T., Weber, T., Graf, R., Sommermann, T., Petsch, K., Sack, U., Volchkov, P., Rajewsky, K. and Kühn, R.
BMC Biotechnology 16
(1): 4.
16 January 2016
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu, V.T., Weber, T., Wefers, B., Wurst, W., Sander, S., Rajewsky, K. and Kühn, R.
Nature Biotechnology 33
(5): 543-548.
May 2015
Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
Chumduri, C., Gillissen, B., Richter, A., Richter, A., Milojkovic, A., Overkamp, T., Mueller, A., Pott, C. and Daniel, P.T.
Journal of Molecular Medicine 93
(5): 559-572.
May 2015
Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response.
Churin, Y., Al Ghoul, L., Kepp, O., Meyer, T.E., Birchmeier, W. and Naumann, M.
Journal of Cell Biology 161
(2): 249-255.
28 April 2003
Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells.
Chyou, S., Benahmed, F., Chen, J., Kumar, V., Tian, S., Lipp, M. and Lu, T.T.
Journal of Immunology 187
(11): 5558-5567.
2 December 2011
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki, F., Bjordahl, R., Goodridge, J.P., Mahmood, S., Gaidarova, S., Abujarour, R., Davis, Z.B., Merino, A., Tuininga, K., Wang, H., Kumar, A., Groff, B., Witty, A., Bonello, G., Huffman, J., Dailey, T., Lee, T.T., Malmberg, K.J., Walcheck, B., Höpken, U., Rehm, A., Valamehr, B. and Miller, J.S.
Nature Communications 13
(1): 7341.
29 November 2022
Titer determination of Ad5 in blood: a cautionary note.
Cichon, G., Boeckh-Herwig, S., Kuemin, D., Hoffmann, C., Schmidt, H.H., Wehnes, E., Haensch, W., Schneider, U., Eckhardt, U., Burger, R. and Pring-Akerblom, P.
Gene Therapy 10
(12): 1012-1017.
June 2003
Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage.
Cichon, G., Willnow, T.E., Herwig, S., Uckert, W., Loeser, P., Schmidt, H.H., Benhidjeb, T., Schlag, P.M., Schnieders, F., Niedzielska, D. and Heeren, J.
Journal of Gene Medicine 6
(2): 166-175.
February 2004
Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C., Rom, A., Franke, V., Imami, K., Arrey, G., Terne, M., Woehler, A., Akalin, A., Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47
(5): 2560-2573.
18 March 2019
Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G., Bay, O., Zinno, J., Gutwein, M., Gan, H.H., Mayya, V.K., Chung, G., Chen, J.X., Fahs, H., Guan, Y., Duchaine, T.F., Selbach, M., Piano, F. and Gunsalus, K.C.
eLife 10
: e60833.
3 August 2021
Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E., Althoff, S., Ruß, J., Rosnev, S., Butze, M., Pühl, M., Frentsch, M., Bullinger, L. and Na, I.K.
International Journal of Molecular Sciences 23
(6): 3207.
16 March 2022
C/EBP-induced transdifferentiation reveals granulocyte-macrophage precursor-like plasticity of B cells.
Cirovic, B., Schönheit, J., Kowenz-Leutz, E., Ivanovska, J., Klement, C., Pronina, N., Bégay, V. and Leutz, A.
Stem Cell Reports 14
(8): 346-359.
14 February 2017
Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR.
Clauss, J., Obenaus, M., Miskey, C., Ivics, Z., Izsvák, Z., Uckert, W. and Bunse, M.
Human Gene Therapy 29
(5): 569-584.
May 2018
Den Weg konsequent weitergehen [The path consequently continues].
Clement, J., Hoeffken, K. and Schlag, P.M.
Onkologe 13
(10): 893.
October 2007
Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum.
Clerc, S., Hirsch, C., Oggier, D.M., Deprez, P., Jakob, C., Sommer, T. and Aebi, M.
Journal of Cell Biology 184
(1): 159-172.
12 January 2009
Low-grade glioma surgery in intraoperative magnetic resonance imaging: Results of a multicenter retrospective assessment of the German Study Group for Intraoperative Magnetic Resonance Imaging.
Coburger, J., Merkel, A., Scherer, M., Schwartz, F., Gessler, F., Roder, C., Pala, A., König, R., Bullinger, L., Nagel, G., Jungk, C., Bisdas, S., Nabavi, A., Ganslandt, O., Seifert, V., Tatagiba, M., Senft, C., Mehdorn, M., Unterberg, A.W., Rössler, K. and Wirtz, C.R.
Neurosurgery 78
(6): 775-86.
June 2016
Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation.
Cocciardi, S., Dolnik, A., Kapp-Schwoerer, S., Rücker, F.G., Lux, S., Blätte, T.J., Skambraks, S., Krönke, J., Heidel, F.H., Schnöder, T.M., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Teleanu, V., Göhring, G., Thol, F., Heuser, M., Ganser, A., Weber, D., Sträng, E., Kestler, H.A., Döhner, H., Bullinger, L. and Döhner, K.
Nature Communications 10
(1): 2031.
2 May 2019
The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.
Coel Arslan, S. and Scheidereit, C.
PLoS ONE 6
(10): e26069.
10 October 2011
miRNAs are essential for the regulation of the PI3K/AKT/FOXO pathway and receptor editing during B cell maturation.
Coffre, M., Benhamou, D., Riess, D., Blumenberg, L., Snetkova, V., Hines, M.J., Chakraborty, T., Bajwa, S., Jensen, K., Chong, M.M.W., Getu, L., Silverman, G.J., Blelloch, R., Littman, D.R., Calado, D., Melamed, D., Skok, J.A., Rajewsky, K. and Koralov, S.B.
Cell Reports 17
(9): 2271-2285.
22 November 2016
Skewed B cell differentiation affects lymphoid organogenesis but not T cell-mediated autoimmunity.
Colombo, E., Tentorio, P., Musio, S., Rajewsky, K., Pedotti, R., Casola, S. and Farina, C.
Clinical and Experimental Immunology 176
(1): 58-65.
April 2014
A roadmap to generate renewable protein binders to the human proteome.
Colwill, K. and Graeslund, S.
Nature Methods 8
(7): 551-558.
15 May 2011
Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes.
Company, C., Schmitt, M.J., Dramaretska, Y., Serresi, M., Kertalli, S., Jiang, B., Yin, J.A., Aguzzi, A., Barozzi, I. and Gargiulo, G.
Nature Communications 15
(1): 897.
5 February 2024
Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Consentius, P., Gohlke, U., Loll, B., Alings, C., Heinemann, U., Wahl, M.C. and Risse, T.
Physical Chemistry Chemical Physics 19
(31): 20723-20734.
9 August 2017
Tracking transient conformational states of T4 lysozyme at room temperature combining X-ray crystallography and site-directed spin labeling.
Consentius, P., Gohlke, U., Loll, B., Alings, C., Mueller, R., Heinemann, U., Kaupp, M., Wahl, M. and Risse, T.
Journal of the American Chemical Society 138
(39): 12868-12875.
5 October 2016
Internal dynamics of the 3-pyrroline-N-oxide ring in spin-labeled proteins.
Consentius, P., Loll, B., Gohlke, U., Alings, C., Müller, C., Müller, R., Teutloff, C., Heinemann, U., Kaupp, M., Wahl, M.C. and Risse, T.
Journal of Physical Chemistry Letters 8
(6): 1113-1117.
16 March 2017
Role of cranial radiotherapy for childhood T-cell acute lymphobalstic leukemia with high WBC count and good response to prednisone.
Conter, V., Schrappe, M., Arico, M., Reiter, A., Rizzari, C., Doerdelmann, M., Valsecchi, M.G., Zimmermann, M., Ludwig, W.D., Basso, G., Masera, G. and Riehm, H.
Journal of Clinical Oncology 15
(8): 2786-2791.
August 1997
PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data.
Corcoran, D.L., Georgiev, S., Mukherjee, N., Gottwein, E., Skalsky, R.L., Keene, J.D. and Ohler, U.
Genome Biology 12
(8): R79.
18 August 2011
Endothelial damage and dysfunction in acute graft-versus-host disease.
Cordes, S., Mokhtari, Z., Bartosova, M., Mertlitz, S., Riesner, K., Shi, Y., Mengwasser, J., Kalupa, M., McGeary, A., Schleifenbaum, J., Schrezenmeier, J., Bullinger, L., Diaz-Ricart, M., Palomo, M., Carrreras, E., Beutel, G., Schmitt, C.P., Beilhack, A. and Penack, O.
Haematologica 106
(8): 2147-2160.
1 August 2020
Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.
Corral, J., Forster, A., Thompson, S., Lampert, F., Kaneko, Y., Slater, R., Kroes, W.G., van der Schoot, C.E., Ludwig, W.D., Karpas, A., Pocock, C., Cotter, F. and Rabitts, T.H.
Proceedings of the National Academy of Sciences of the United States of America 90
(18): 8538-8542.
15 September 1993
A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis.
Coscia, F., Doll, S., Bech, J.M., Schweizer, L., Mund, A., Lengyel, E., Lindebjerg, J., Madsen, G.I., Moreira, J.M. and Mann, M.
Journal of Pathology 251
(1): 100-112.
May 2020
Multi-level proteomics identifies CT45 as a chemosensitivity mediator and immunotherapy target in ovarian cancer.
Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S.D., López-Méndez, B., Nilsson, J., Mund, A., Mann, M. and Curtis, M.
Cell 175
(1): 159-170.
20 September 2018
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Coscia, F., Watters, K.M., Curtis, M., Eckert, M.A., Chiang, C.Y., Tyanova, S., Montag, A., Lastra, R.R., Lengyel, E. and Mann, M.
Nature Communications 7
: 12645.
26 August 2016
Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription.
Cossa, G., Roeschert, I., Prinz, F., Baluapuri, A., Silveira Vidal, R., Schülein-Völk, C., Chang, Y.C., Ade, C.P., Mastrobuoni, G., Girard, C., Kumar, A., Wortmann, L., Walz, S., Lührmann, R., Kempa, S., Kuster, B., Wolf, E., Mumberg, D. and Eilers, M.
Molecular Cell 77
(6): 1322-1339.
19 March 2020
Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP.
Courtial, N., Smink, J.J., Kuvardina, O.N., Leutz, A., Goethert, J.R. and Lausen, J.
FASEB Journal 26
(2): 523-532.
February 2012
Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Creutzig, U., Harbott, J., Sperling, C., Ritter, J., Zimmermann, M., Loeffler, H., Riehm, H., Schellong, G. and Ludwig, W.D.
Blood 86
(8): 3097-3108.
1 October 1995
Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.
Cui, H., Bansal, V., Grunert, M., Malecova, B., Dall Agnese, A., Latella, L., Gatto, S., Ryan, T., Schulz, K., Chen, W., Dorn, C., Puri, P.L. and Sperling, S.R.
PLoS ONE 12
(6): e0179464.
13 June 2017
Hemostatic management in an infant with neuroblastoma and severe hemophilia B with extended half-life recombinant factor IX fusion protein.
Cuntz, F., Deubzer, H.E., Schulte, J.H., Nimtz-Talaska, A., Eggert, A. and Holzhauer, S.
Journal of Pediatric Hematology Oncology 44
(1): e246-e249.
1 January 2022
Cryoelectron tomography reveals periodic material at the inner side of subpellicular microtubules in apicomplexan parasites.
Cyrklaff, M., Kudryashev, M., Leis, A., Leonard, K., Baumeister, W., Menard, R., Meissner, M. and Frischknecht, F.
Journal of Experimental Medicine 204
(6): 1281-1287.
11 June 2007
The immune response to sporadic colorectal cancer in a novel mouse model.
Czeh, M., Loddenkemper, C., Shalapour, S., Schoen, C., Robine, S., Goldscheid, E., Stein, H., Schueler, T., Willimsky, G. and Blankenstein, T.
Oncogene 29
(50): 6591-6602.
16 December 2010
Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2.
D'Orazio, D., Besser, D., Marksitzer, R., Kunz, C., Hume, D.A., Kiefer, B. and Nagamine, Y.
Gene 201
(1-2): 179-187.
12 November 1997
Expression of genes controlling testicular development in adult testis of the seasonally breeding iberian mole.
Dadhich, R.K., Barrionuevo, F.J., Lupianez, D.G., Real, F.M., Burgos, M. and Jimenez, R.
Sexual Development 5
(2): 77-88.
March 2011
Identification of live germ-cell desquamation as a major mechanism of seasonal testis regression in mammals: a study in the Iberian mole (Talpa occidentalis).
Dadhich, R.K., Barrionuevo, F.J., Real, F.M., Lupiañez, D.G., Ortega, E., Burgos, M. and Jiménez, R.
Biology of Reproduction 88
(4): 101.
1 April 2013
RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.
Dahlmann, M., Okhrimenko, A., Marcinkowski, P., Osterland, M., Herrmann, P., Smith, J., Heizmann, C.W., Schlag, P.M. and Stein, U.
Oncotarget 5
(10): 3220-3233.
30 May 2014
Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.
Dahlmann, M., Sack, U., Herrmann, P., Lemm, M., Fichtner, I., Schlag, P.M. and Stein, U.
Oncotarget 3
(8): 783-797.
7 August 2012
RNA interference for antimetastatic therapy.
Dahlmann, M. and Stein, U.
Methods in Molecular Biology 1317
: 153-165.
2015
Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M., Monks, A., Harris, E.D., Kobelt, D., Osterland, M., Khaireddine, F., Herrmann, P., Kemmner, W., Burock, S., Walther, W., Shoemaker, R.H. and Stein, U.
Cancers 14
(1): 37.
2022
A bioinformatic pipeline to identify biomarkers for metastasis formation from RNA sequencing data.
Dahlmann, M. and Stein, U.S.
Methods in Molecular Biology 2294
: 221-238.
2021
Restoring treatment response in colorectal cancer cells by targeting MACC1-dependent ABCB1 expression in combination therapy.
Dahlmann, M., Werner, R., Kortüm, B., Kobelt, D., Walther, W. and Stein, U.
Frontiers in Oncology 10
: 599.
23 April 2020
Treatment of oesophageal anastomotic leaks by temporary stenting with self-expanding plastic stents.
Dai, Y.Y., Gretschel, S., Dudeck, O., Rau, B., Schlag, P.M. and Huenerbein, M.
British Journal of Surgery 96
(8): 887-891.
August 2009
Early bilirubinemia after allogeneic stem cell transplantation - an endothelial complication.
Dai, H., Penack, O., Radujkovic, A., Schult, D., Majer-Lauterbach, J., Blau, I.W., Bullinger, L., Jiang, S., Müller-Tidow, C., Dreger, P. and Luft, T.
Bone Marrow Transplantation 56
(7): 1573-1583.
July 2021
Novel targets of protoporphyrin-IX determined by gene expression analysis.
Dai, Y. and Kemmner, W.
International Journal of Clinical Oncology and Cancer Research 5
(3): 56-64.
September 2020
Genome-wide analysis of barrett's adenocarcinoma. a first step towards identifying patients at risk and developing therapeutic paths.
Dai, Y., Wang, Q., Gonzalez Lopez, A., Anders, M., Malfertheiner, P., Vieth, M. and Kemmner, W.
Translational Oncology 11
(1): 116-124.
February 2018
Covering hierarchical dirichlet mixture models on binary data to enhance genomic stratifications in onco-hematology.
Dall'Olio, D., Sträng, E., Turki, A.T., Tettero, J.M., Barbus, M., Schulze-Rath, R., Elicegui, J.M., Matteuzzi, T., Merlotti, A., Carota, L., Sala, C., Della Porta, M.G., Giampieri, E., Hernández-Rivas, J.M., Bullinger, L. and Castellani, G.
PLoS Computational Biology 20
(2): e1011299.
2 February 2024
Molekulare Grundlagen der zielgerichteten Tumortherapie [The molecular bases of targeted tumor therapy].
Daniel, P.
Onkologe 13
(1): 8-19.
January 2007
Grundlagen der molekularen Diagnostik und Therapie maligner Tumoren [Basics of molecular diagnostics and therapy of malignant tumors].
Daniel, P.T. and Doerken, B.
Internist 46
(8): 835-846.
12 July 2005
Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T., Kroidl, A., Kopp, J., Sturm, I., Moldenhauer, G., Doerken, B. and Pezzutto, A.
Blood 92
(12): 4750-4757.
15 December 1998
Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.
Daniel, P.T., Kroidl, A., Cayeux, S., Bargou, R.C., Blankenstein, T. and Doerken, B.
Journal of Immunology 159
(8): 3808-3815.
15 October 1997
PankoMab: a potent new generation anti-tumour MUC1 antibody.
Danielczyk, A., Stahn, R., Faulstich, D., Loeffler, A., Maerten, A., Karsten, U. and Goletz, S.
Cancer Immunology Immunotherapy 55
(11): 1337-1347.
November 2006
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Danielli, S.G., Porpiglia, E., De Micheli, A.J., Navarro, N., Zellinger, M.J., Bechtold, I., Kisele, S., Volken, L., Marques, J.G., Kasper, S., Bode, P.K., Henssen, A.G., Gürgen, D., Delattre, O., Surdez, D., Roma, J., Bühlmann, P., Blau, H.M., Wachtel, M. and Schäfer, B.W.
Science Advances 9
(6): eade9238.
10 February 2023
The pierced lasso topology leptin has a bolt on dynamic domain composed by the disordered loops I and III.
Danielsson, J., Noel, J.K., Simien, J.M., Duggan, B.M., Oliveberg, M., Onuchic, J.N., Jennings, P.A. and Haglund, E.
Journal of Molecular Biology 432
(9): 3050-3063.
17 April 2020
Control of gene editing by manipulation of DNA repair mechanisms.
Danner, E., Bashir, S., Yumlu, S., Wurst, W., Wefers, B. and Kühn, R.
Mammalian Genome 28
(7-8): 262-274.
August 2017
A homology independent sequence replacement strategy in human cells using a CRISPR nuclease.
Danner, E., Lebedin, M., de la Rosa, K. and Kühn, R.
Open Biology 11
(1): 200283.
January 2021
T cells engineered to express a T-cell receptor specific for glypican-3 recognize and kill hepatoma cells in vitro and in mice.
Dargel, C., Bassani-Sternberg, M., Hasreiter, J., Zani, F., Bockmann, J.H., Thiele, F., Bohne, F., Wisskirchen, K., Wilde, S., Sprinzl, M.F., Schendel, D.J., Krackhardt, A.M., Uckert, W., Wohlleber, D., Schiemann, M., Stemmer, K., Heikenwälder, M., Busch, D.H., Richter, G., Mann, M. and Protzer, U.
Gastroenterology 149
(4): 1042-1052.
October 2015
GPR56 contributes to the development of acute myeloid leukemia in mice.
Daria, D., Kirsten, N., Muranyi, A., Mulaw, M., Ihme, S., Kechter, A., Hollnagel, M., Bullinger, L., Döhner, K., Döhner, H., Feuring-Buske, M. and Buske, C.
Leukemia 30
(8): 1734-1741.
August 2016
Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture.
Dasgupta, S., Dayagi, D.Y., Haimovich, G., Wyler, E., Olender, T., Singer, R.H., Landthaler, M. and Gerst, J.E.
eLife 12
: e83584.
30 May 2023
Generation of an antibody against the protein phosphatase 1 inhibitor KEPI and characterization of the epitope.
Daskalow, K., Boisguerin, P., Jandrig, B., Van Landeghem, F.K., Volkmer, R., Micheel, B. and Schenk, J.A.
Anticancer Research 30
(5): 1573-1578.
May 2010
Epitope mapping of antibodies against S-tagged fusion proteins and molecular weight markers.
Daskalow, K., Boisguerin, P., Jandrig, B., Volkmer, R., Micheel, B. and Schenk, J.A.
Bioscience, Biotechnology, and Biochemistry 72
(2): 346-351.
February 2008
Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module.
Daumke, O., Gao, S., von der Malsburg, A., Haller, O. and Kochs, G.
Small GTPases 1
(1): 62-64.
July 2010
Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
Daumke, O., Lundmark, R., Vallis, Y., Martens, S., Butler, P.J.G. and McMahon, H.T.
Nature 449
(7164): 923-927.
3 October 2007
Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains.
Daumke, O. and Knittler, M.R.
European Journal of Biochemistry 268
(17): 4776-86.
September 2001
The GTPase-activating protein Rap1GAP uses a catalytic asparagine.
Daumke, O., Weyand, M., Chakrabarti, P.P., Vetter, I.R. and Wittinghofer, A.
Nature 429
(6988): 197-201.
13 May 2004
Purification, crystallization and preliminary structural characterization of human Rap1GAP.
Daumke, O., Wittinghofer, A. and Weyand, M.
Acta Crystallographica Section D : Structural Biology 60
(Pt 4): 752-4.
April 2004
Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.
Dawson, M.A., Gudgin, E.J., Horton, S.J., Giotopoulos, G., Meduri, E., Robson, S., Cannizzaro, E., Osaki, H., Wiese, M., Putwain, S., Fong, C.Y., Grove, C., Craig, J., Dittmann, A., Lugo, D., Jeffrey, P., Drewes, G., Lee, K., Bullinger, L., Prinjha, R.K., Kouzarides, T., Vassiliou, G.S. and Huntly, B.J.P.
Leukemia 28
(2): 311-320.
February 2014
Systematic benchmarking of single-cell ATAC-sequencing protocols.
De Rop, F.V., Hulselmans, G., Flerin, C., Soler-Vila, P., Rafels, A., Christiaens, V., González-Blas, C.B., Marchese, D., Caratù, G., Poovathingal, S., Rozenblatt-Rosen, O., Slyper, M., Luo, W., Muus, C., Duarte, F., Shrestha, R., Bagdatli, S.T., Corces, M.R., Mamanova, L., Knights, A., Meyer, K.B., Mulqueen, R., Taherinasab, A., Maschmeyer, P., Pezoldt, J., Lambert, C.L.G., Iglesias, M., Najle, S.R., Dossani, Z.Y., Martelotto, L.G., Burkett, Z., Lebofsky, R., Martin-Subero, J.I., Pillai, S., Sebé-Pedrós, A., Deplancke, B., Teichmann, S.A., Ludwig, L.S., Braun, T.P., Adey, A.C., Greenleaf, W.J., Buenrostro, J.D., Regev, A., Aerts, S. and Heyn, H.
Nature Biotechnology 42
(6): 916-926.
June 2024
Mutant FUS and ELAVL4 (HuD) aberrant crosstalk in amyotrophic lateral sclerosis.
De Santis, R., Alfano, V., de Turris, V., Colantoni, A., Santini, L., Garone, M.G., Antonacci, G., Peruzzi, G., Sudria-Lopez, E., Wyler, E., Anink, J.J., Aronica, E., Landthaler, M., Pasterkamp, R.J., Bozzoni, I. and Rosa, A.
Cell Reports 27
(13): 3818-3831.
25 June 2019
TIM-3 and CEACAM1 do not interact in cis and in trans.
De Sousa Linhares, A., Kellner, F., Jutz, S., Zlabinger, G.J., Gabius, H.J., Huppa, J.B., Leitner, J. and Steinberger, P.
European Journal of Immunology 50
(8): 1126-1141.
August 2020
Suspension medium influences interaction of mesenchymal stromal cells with endothelium and pulmonary toxicity after transplantation in mice.
Deak, E., Ruester, B., Keller, L., Eckert, K., Fichtner, I., Seifried, E. and Henschler, R.
Cytotherapy 12
(2): 260-264.
April 2010
Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues.
Debes, G.F., Arnold, C.N., Young, A.J., Krautwald, S., Lipp, M., Hay, J.B. and Butcher, E.C.
Nature Immunology 6
(9): 889-894.
14 August 2005
In vivo differentiated cytokine-producing CD4+ T cells express functional CCR7.
Debes, G.F., Höpken, U.E. and Hamann, A.
Journal of Immunology 168
(11): 5441-5447.
1 June 2002
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Decaesteker, B., Denecker, G., Van Neste, C., Dolman, E.M., Van Loocke, W., Gartlgruber, M., Nunes, C., De Vloed, F., Depuydt, P., Verboom, K., Rombaut, D., Loontiens, S., De Wyn, J., Kholosy, W.M., Koopmans, B., Essing, A.H.W., Herrmann, C., Dreidax, D., Durinck, K., Deforce, D., van Nieuwerburgh, F., Henssen, A., Versteeg, R., Boeva, V., Schleiermacher, G., van Nes, J., Mestdagh, P., Vanhauwaert, S., Schulte, J.H., Westermann, F., Molenaar, J.J., De Preter, K. and Speleman, F.
Nature Communications 9
(1): 4866.
19 November 2018
GP130 activation induces myeloma and collaborates with MYC.
Dechow, T., Steidle, S., Götze, K.S., Rudelius, M., Behnke, K., Pechloff, K., Kratzat, S., Bullinger, L., Fend, F., Soberon, V., Mitova, N., Li, Z., Thaler, M., Bauer, J., Pietschmann, E., Albers, C., Grundler, R., Schmidt-Supprian, M., Ruland, J., Peschel, C., Duyster, J., Rose-John, S., Bassermann, F. and Keller, U.
Journal of Clinical Investigation 124
(12): 5263-5274.
1 December 2014
Thyrotropin receptor-specific lymphocytes in adenovirus-TSHR-immunized native and human leukocyte antigen-DR3-transgenic mice and in Graves' disease patient blood.
Degen, H., Gavvovidis, I., Blankenstein, T., Uhland, K. and Ungerer, M.
Thyroid 31
(6): 950-963.
June 2021
Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism.
Degiacomi, M.T., Iacovache, I., Pernot, L., Chami, M., Kudryashev, M., Stahlberg, H., van der Goot, F.G. and Dal Peraro, M.
Nature Chemical Biology 9
(10): 623-629.
October 2013
Self-organization of human embryonic stem cells on micropatterns.
Deglincerti, A., Etoc, F., Guerra, M.C., Martyn, I., Metzger, J., Ruzo, A., Simunovic, M., Yoney, A., Brivanlou, A.H., Siggia, E. and Warmflash, A.
Nature Protocols 11
(11): 2223-2232.
November 2016
Random focusing of tsunami waves.
Degueldre, H., Metzger, J.J., Geisel, T. and Fleischmann, R.
Nature Physics 12
(3): 259-262.
March 2016
Channeling of branched flow in weakly scattering anisotropic media.
Degueldre, H., Metzger, J.J., Schultheis, E. and Fleischmann, R.
Physical Review Letters 118
(2): 024301.
13 January 2017
Interleukin-7 modulates anti-tumor CD8+ T cell responses via its action on host cells.
Deiser, K., Stoycheva, D., Bank, U., Blankenstein, T. and Schüler, T.
PLoS ONE 11
(7): e0159690.
22 July 2016
The MYCmRNA3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.
Dejure, F.R., Royla, N., Herold, S., Kalb, J., Walz, S., Ade, C.P., Mastrobuoni, G., Vanselow, J.T., Schlosser, A., Wolf, E., Kempa, S. and Eilers, M.
EMBO Journal 36
(13): 1854-1868.
3 July 2017
Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney.
Dekel, B., Metsuyanim, S., Schmidt-Ott, K.M., Fridman, E., Jacob-Hirsch, J., Simon, A., Pinthus, J., Mor, Y., Barasch, J., Amariglio, N. and Reisner, Y.
Cancer Research 66
(12): 6040-6049.
15 June 2006
Small-molecule inhibition of APT1 affects Ras localization and signaling.
Dekker, F.J., Rocks, O., Vartak, N., Menninger, S., Hedberg, C., Balamurugan, R., Wetzel, S., Renner, S., Gerauer, M., Schoelermann, B., Rusch, M., Kramer, J.W., Rauh, D., Coates, G.W., Brunsveld, L., Bastiaens, P.I. and Waldmann, H.
Nature Chemical Biology 6
(6): 449-456.
June 2010
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V., Berruezo-Llacuna, M., Altwasser, R., Winkler, W., Sundaravinayagam, D., Balasubramanian, S., Caganova, M., Graf, R., Rahjouei, A., Henke, M.T., Driesner, M., Keller, L., Prigione, A., Janz, M., Akalin, A. and Di Virgilio, M.
Journal of Experimental Medicine 217
(10): e20200137.
5 October 2020
The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V., Rosen, D.B., Wang, Q., Gazumyan, A., Pai, J.A., Oliveira, T.Y., Sundaravinayagam, D., Zhang, W., Andreani, M., Keller, L., Kieffer-Kwon, K.R., Pękowska, A., Jung, S., Driesner, M., Subbotin, R.I., Casellas, R., Chait, B.T., Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72
(4): 636-649.
15 November 2018
Stage-specific metabolic features of differentiating neurons: implications for toxicant sensitivity.
Delp, J., Gutbier, S., Cerff, M., Zasada, C., Niedenführ, S., Zhao, L., Smirnova, L., Hartung, T., Borlinghaus, H., Schreiber, F., Bergemann, J., Gätgens, J., Beyss, M., Azzouzi, S., Waldmann, T., Kempa, S., Nöh, K. and Leist, M.
Toxicology and Applied Pharmacology 354
: 64-80.
1 September 2018
The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3β interaction protein (GSKIP) regulates β-catenin through its interactions with both protein kinase A (PKA) and GSK3β.
Dema, A., Schröter, M.F., Perets, E., Skroblin, P., Moutty, M.C., Deàk, V.A., Birchmeier, W. and Klussmann, E.
Journal of Biological Chemistry 291
(37): 19618-19630.
9 September 2016
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P., Newman, A.G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., Kleinau, G., Derkow, K., Richard, B.C., Schipke, C., Scheidereit, C., Stachelscheid, H., Golenbock, D., Peters, O., Coleman, M., Heppner, F.L., Scheerer, P., Tarabykin, V., Ruprecht, K., Izsvák, Z., Mayer, J. and Lehnardt, S.
JCI Insight 5
(7): e131093.
9 April 2020
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Demel, U.M., Böger, M., Yousefian, S., Grunert, C., Zhang, L., Hotz, P.W., Gottschlich, A., Köse, H., Isaakidis, K., Vonficht, D., Grünschläger, F., Rohleder, E., Wagner, K., Dönig, J., Igl, V., Brzezicha, B., Baumgartner, F., Habringer, S., Löber, J., Chapuy, B., Weidinger, C., Kobold, S., Haas, S., Busse, A.B., Müller, S., Wirth, M., Schick, M. and Keller, U.
Journal of Clinical Investigation 132
(9): e152383.
2 May 2022
A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo.
Demel, U.M., Lutz, R., Sujer, S., Demerdash, Y., Sood, S., Grünschläger, F., Kuck, A., Werner, P., Blaszkiewicz, S., Uckelmann, H.J., Haas, S. and Essers, M.
Blood Advances 6
(11): 3513-3528.
10 June 2022
Small molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy.
Demel, U.M., Wirth, M., Yousefian, S., Zhang, L., Isaakidis, K., Dönig, J., Böger, M., Singh, N., Köse, H., Haas, S., Müller, S., Schick, M. and Keller, U.
Haematologica 108
(2): 555-567.
February 2023
Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S., Bittner, A., Frick, M., Kase, J., Hoffmann, J., Trenker, C., Keller, U., Bogner, C., Hüttmann, A., Dürig, J., Janz, M., Mathas, S., Marks, R., Krohn, U., Na, I.K., Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 63
(1): 84-92.
January 2022
A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response.
Denker, S., Bittner, A., Na, I.K., Kase, J., Frick, M., Anagnostopoulos, I., Hummel, M. and Schmitt, C.A.
International Journal of Hematologic Oncology 8
(4): IJH20.
19 December 2019
Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference.
Denkert, C., Fuerstenberg, A., Daniel, P.T., Koch, I., Koebel, M., Weichert, W., Siegert, A. and Hauptmann, S.
Oncogene 22
(54): 8653-8661.
27 November 2003
Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.
Denkinger, C.M., Janssen, M., Schäkel, U., Gall, J., Leo, A., Stelmach, P., Weber, S.F., Krisam, J., Baumann, L., Stermann, J., Merle, U., Weigand, M.A., Nusshag, C., Bullinger, L., Schrezenmeier, J.F., Bornhäuser, M., Alakel, N., Witzke, O., Wolf, T., Vehreschild, M.J.G.T., Schmiedel, S., Addo, M.M., Herth, F., Kreuter, M., Tepasse, P.R., Hertenstein, B., Hänel, M., Morgner, A., Kiehl, M., Hopfer, O., Wattad, M.A., Schimanski, C.C., Celik, C., Pohle, T., Ruhe, M., Kern, W.V., Schmitt, A., Lorenz, H.M., Souto-Carneiro, M., Gaeddert, M., Halama, N., Meuer, S., Kräusslich, H.G., Müller, B., Schnitzler, P., Parthé, S., Bartenschlager, R., Gronkowski, M., Klemmer, J., Schmitt, M., Dreger, P., Kriegsmann, K., Schlenk, Ri.F. and Müller-Tidow, C.
Nature Cancer 4
(1): 96-107.
January 2023
Hexosamine pathway metabolites enhance protein quality control and prolong life.
Denzel, M.S., Storm, N.J., Gutschmidt, A., Baddi, R., Hinze, Y., Jarosch, E., Sommer, T., Hoppe, T. and Antebi, A.
Cell 156
(6): 1167-1178.
13 March 2014
Third-generation anti-CD19 CAR T cells for relapsed/refractory chronic lymphocytic leukemia: a phase 1/2 study.
Derigs, P., Schubert, M.L., Dreger, P., Schmitt, A., Yousefian, S., Haas, S., Röthemeier, C., Neuber, B., Hückelhoven-Krauss, A., Brüggemann, M., Bernhard, H., Kobbe, G., Lindemann, A., Rummel, M., Michels, B., Korell, F., Ho, A.D., Müller-Tidow, C. and Schmitt, M.
Leukemia 38
(11): 2419-2428.
November 2024
Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E., Herzog, S., Labi, V., Yasuda, T., Köchert, K., Janz, M., Villunger, A., Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113
(18): 5065-5070.
3 May 2016
Elevated Flt3L predicts long-term survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms.
Detjen, K.M., Otto, R., Giesecke, Y., Geisler, L., Riemer, P., Jann, H., Grötzinger, C., Sers, C., Pascher, A., Lüdde, T., Leser, U., Wiedenmann, B., Sigal, M., Tacke, F., Roderburg, C. and Hammerich, L.
Cancers 13
(17): 4463.
1 September 2021
Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells.
Deubzer, H., Busche, B., Rönndahl, G., Eikel, D., Michaelis, M., Cinatl, J., Schulze, S., Nau, H. and Witt, O.
Leukemia Research 30
(9): 1167-1175.
September 2006
„Liquid biopsies“ als neue Diagnostikplattform in der pädiatrischen Onkologie [Liquid biopsies as a new diagnostic platform in pediatric oncology].
Deubzer, H.E., Eggert, A. and Pajtler, K. W.
Onkologe 27
(5): 458-463.
May 2021
Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro.
Deubzer, H.E., Ehemann, V., Kulozik, A.E., Westermann, F., Savelyeva, L., Kopp-Schneider, A., Riester, D., Schwab, M. and Witt, O.
Cancer Letters 264
(1): 21-28.
8 June 2008
Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.
Deubzer, H.E., Ehemann, V., Westermann, F., Heinrich, R., Mechtersheimer, G., Kulozik, A.E., Schwab, M. and Witt, O.
International Journal of Cancer 122
(8): 1891-900.
15 April 2008
Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae.
Deubzer, H.E., Obaro, S.K., Newman, V.O., Adegbola, R.A., Greenwood, B.M. and Henderson, D.C.
Journal of Infectious Diseases 190
(10): 1758-1761.
15 November 2004
HDAC11 is a novel drug target in carcinomas.
Deubzer, H.E., Schier, M.C., Oehme, I., Lodrini, M., Haendler, B., Sommer, A. and Witt, O.
International Journal of Cancer 132
(9): 2200-2208.
1 May 2013
HMGXB4 targets Sleeping Beauty transposition to germinal stem cells.
Devaraj, A., Singh, M., Narayanavari, S.A., Yong, G., Chen, J., Wang, J., Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z., Raskó, T., Radscheit, K., Selbach, M., Ivics, Z. and Izsvak, Z.
International Journal of Molecular Sciences 24
(8): 7283.
14 April 2023
Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress.
Devos, S., Van Putte, W., Vitse, J., Van Driessche, G., Stremersch, S., Van Den Broek, W., Raemdonck, K., Braeckmans, K., Stahlberg, H., Kudryashev, M., Savvides, S.N. and Devreese, B.
Environmental Microbiology 19
(10): 3930-3937.
October 2017
The BTB/POZ domain targets the LAZ3/BCL6 oncoprotein to nuclear dots and mediates homomerisation in vivo.
Dhordain, P., Albagli, O., Ansieau, S., Koken, M., Deweindt, C., Quief, S., Lantoine, D., Leutz, A., Kerckaert, J.P. and Leprince, D.
Oncogene 11
(12): 2689-2697.
21 December 1995
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.
Di Micco, R., Sulli, G., Dobreva, M., Liontos, M., Botrugno, O.A., Gargiulo, G., dal Zuffu, R., Matti, V., d'Ario, G., Montani, E., Mercurio, C., Hahn, W.C., Gorgoulis, V., Minucci, S. and d'Adda di Fagagna, F.
Nature Cell Biology 13
(3): 292-302.
March 2011
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Di Virgilio, M., Callen, E., Yamane, A., Zhang, W., Jankovic, M., Gitlin, A.D., Feldhahn, N., Resch, W., Oliveira, T.Y., Chait, B.T., Nussenzweig, A., Casellas, R., Robbiani, D.F. and Nussenzweig, M.C.
Science 339
(6120): 711-715.
8 February 2013
PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin.
Di Virgilio, M., Ying, C.Y. and Gautier, J.
DNA Repair 8
(11): 1311-1320.
2 November 2009
Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11.
Di Virgilio, M. and Gautier, J.
Journal of Cell Biology 171
(5): 765-771.
5 December 2005
Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.
Dias D'Andréa, E., Roske, Y., de Oliveira, G.A.P., Cremer, N., Diehl, A., Schmieder, P., Heinemann, U., Oschkinat, H. and Ricardo Pires, J.
Journal of Structural Biology 211
(2): 107536.
1 August 2020
Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies.
Diaz Miqueli, A., Rolff, J., Lemm, M., Fichtner, I., Perez, R. and Montero, E.
British Journal of Cancer 100
(6): 950-958.
24 March 2009
Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.
Dick, A., Graf, L., Olal, D., von der Malsburg, A., Gao, S., Kochs, G. and Daumke, O.
Journal of Biological Chemistry 290
(20): 12779-12792.
15 May 2015
Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly.
Dick, A., Mikirtumov, V., Fuchs, J., Krupp, F., Olal, D., Bendl, E., Sprink, T., Diebolder, C., Kudryashev, M., Kochs, G., Roske, Y. and Daumke, O.
Structure 32
(8): 1068-1078.
8 August 2024
Enhancement of tumour-specific immune responses in vivo by 'MHC Loading-Enhancer' (MLE).
Dickhaut, K., Hoepner, S., Eckhard, J., Wiesmueller, K.H., Schindler, L., Jung, G., Falk, K. and Roetzschke, O.
PLoS ONE 4
(9): e6811.
7 September 2009
HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy.
Dickson, G.J., Liberante, F.G., Kettyle, L.M., O'Hagan, K.A., Finnegan, D.P.J., Bullinger, L., Geerts, D., McMullin, M.F., Lappin, T.R.J., Mills, K.I. and Thompson, A.
Haematologica 98
(8): 1216-25.
August 2013
FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells.
Diecke, S., Quiroga-Negreira, A., Redmer, T. and Besser, D.
Cells Tissues Organs 188
(1-2): 52-61.
July 2008
Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
Dieckmann, S., Strohmeyer, A., Willershäuser, M., Maurer, S.F., Wurst, W., Marschall, S., Hrabě de Angelis, M., Kühn, R., Worthmann, A., Fuh, M.M., Heeren, J., Köhler, N., Pauling, J.K. and Klingenspor, M.
American Journal of Physiology Endocrinology and Metabolism 322
(2): E85-E100.
February 2022
Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkins disease.
Diehl, V., Franklin, J., Pfreundschuh, M., Lathan, B., Paulus, U., Hasenclever, D., Tesch, H., Herrmann, R., Doerken, B., Mueller-Hermelink, H.K., Duehmke, E. and Loeffler, M.
New England Journal of Medicine 348
(24): 2386-2395.
12 June 2003
Structural changes of TasA in biofilm formation of Bacillus subtilis.
Diehl, A., Roske, Y., Ball, L., Chowdhury, A., Hiller, M., Molière, N., Kramer, R., Stöppler, D., Worth, C.L., Schlegel, B., Leidert, M., Cremer, N., Erdmann, N., Lopez, D., Stephanowitz, H., Krause, E., van Rossum, B.J., Schmieder, P., Heinemann, U., Turgay, K., Akbey, Ü. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 115
(13): 3237-3242.
27 March 2018
Differentiation of effector/memory V ae 2 T cells and migratory routes in lymph nodes or inflammatory sites.
Dieli, F., Poccia, F., Lipp, M., Sireci, G., Caccamo, N., Di Sano, C. and Salerno, A.
Journal of Experimental Medicine 198
(3): 391-397.
4 August 2003
Composition, formation, and regulation of the cytosolic c-ring, a dynamic component of the type III secretion injectisome.
Diepold, A., Kudryashev, M., Delalez, N.J., Berry, R.M. and Armitage, J.P.
PLoS Biology 13
(1): e1002039.
15 January 2015
Reconstruction of optical properties of phantom and breast lesion in vivo from paraxial scanning data.
Dierkes, T., Grosenick, D., Moesta, K.T., Moeller, M., Schlag, P.M., Rinneberg, H. and Arridge, S.
Physics in Medicine and Biology 50
: 2519-2542.
1 January 2005
Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S., Company, C., Song, K., Lowenstein, E.D., Riedel, L., Birchmeier, C., Gargiulo, G. and Zampieri, N.
Nature Communications 13
(1): 6867.
11 November 2022
Cysteine engineering of polyproteins for single-molecule force spectroscopy.
Dietz, H., Bertz, M., Schlierf, M., Berkemeier, F., Bornschloegl, T., Junker, J.P. and Rief, M.
Nature Protocols 1
(1): 80-84.
2006
Ventricular remodeling after acute myocardial infarction.
Dietz, R., Osterziel, K.J., Willenbrock, R., Gulba, D.C. and von Harsdorf, R.
Thrombosis and Haemostasis 82
(Suppl 1): 73-75.
September 1999
Structure of the merozoite surface protein 1 from Plasmodium falciparum.
Dijkman, P.M., Marzluf, T., Zhang, Y., Chang, S.Y.S., Helm, D., Lanzer, M., Bujard, H. and Kudryashev, M.
Science Advances 7
(23): eabg0465.
June 2021
Comparison of R-CHOP-14 and R-mini-CHOP in older adults with diffuse large B-cell lymphoma - a retrospective multicenter cohort study.
Dilbaz, Z.G., Denker, S., Ankermann, C., Bittenbring, J.T., Kaddu-Mulindwa, D., Kunte, A.S., Hünecke, S., Poeschel, V., Stilgenbauer, S., Thurner, L., Na, I.K., Bewarder, M. and Christofyllakis, K.
European Journal of Haematology 113
(5): 675-684.
November 2024
COVID19-associated cardiomyocyte dysfunction, arrhythmias and the effect of Canakinumab.
Dimai, S., Semmler, L., Prabhu, A., Stachelscheid, H., Huettemeister, J., Klaucke, S.C., Lacour, P., Blaschke, F., Kruse, J., Parwani, A., Boldt, L.H., Bullinger, L., Pieske, B.M., Heinzel, F.R. and Hohendanner, F.
PLoS ONE 16
(8): e0255976.
19 August 2021
Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast.
Dimmer, K.S., Jakobs, S., Vogel, F., Altmann, K. and Westermann, B.
Journal of Cell Biology 168
(1): 103-115.
3 January 2005
Genome-wide search for miRNA-target interactions in Arabidopsis thaliana with an integrated approach.
Ding, J., Li, D., Ohler, U., Guan, J. and Zhou, S.
BMC Genomics 13
(Suppl 3): S3.
11 June 2012
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
Ding, Q., Xia, W., Liu, J.C., Yang, J.Y., Lee, D.F., Xia, J., Bartholomeusz, G., Li, Y., Pan, Y., Li, Z., Bargou, R.C., Qin, J., Lai, C.C., Tsai, F.J., Tsai, C.H. and Hung, M.C.
Molecular Cell 19
: 159-170.
1 January 2005
PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
Dittmar, G., Perez Hernandez, D., Kowenz-Leutz, E., Kirchner, M., Kahlert, G., Wesolowski, R., Baum, K., Knoblich, M., Hofstätter, M., Muller, A., Wolf, J., Reimer, U. and Leutz, A.
iScience 13
: 351-370.
29 March 2019
Molecular dynamics simulations of the 136 unique tetranucleotide sequences of DNA oligonucleotides. II. Sequence context effects on the dynamical structures of the 10 unique dinucleotide steps.
Dixit, S.B., Beveridge, D.L., Case, D.A., Cheatham, T.E., Guidice, E., Lankas, F., Lavery, R., Maddocks, J.H., Osman, R., Sklenar, H., Thayer, K. and Varnai, P.
Biophysical Journal 89
(6): 3721-3740.
December 2005
Clinical utility of a protein-based oncopanel in patients with end-stage head and neck cancer.
Doescher, J., Weissinger, S.E., Schönsteiner, S.S., Lisson, C., Bullinger, L., Barth, T.F., Leithäuser, F., Mueller-Richter, U., Laban, S., Hoffmann, T.K., Möller, P., Lennerz, J.K. and Schuler, P.J.
Immunotherapy 11
(14): 1193-1203.
October 2019
NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
Doffo, J., Bamopoulos, S.A., Köse, H., Orben, F., Zang, C., Pons, M., den Dekker, A.T., Brouwer, R.W.W., Baluapuri, A., Habringer, S., Reichert, M., Illendula, A., Krämer, O.H., Schick, M., Wolf, E., van IJcken, W.F.J., Esposito, I., Keller, U., Schneider, G. and Wirth, M.
Proceedings of the National Academy of Sciences of the United States of America 119
(9): e2105691119.
1 March 2022
Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient.
Doll, S., Kriegmair, M.C., Santos, A., Wierer, M., Coscia, F., Neil, H.M., Porubsky, S., Geyer, P.E., Mund, A., Nuhn, P. and Mann, M.
Molecular Oncology 12
(8): 1296-1307.
August 2018
Zukunfts-Szenarien: Szenario-Workshop mit Laien und Experten zu moeglichen Einfluessen der Wirtschaft auf die biomedizinische Forschung.
Domasch, S.
GenomXpress 3
: 18.
March 2003
Transparenz und Erfahrbarkeit von Wissen - Bioethik und Wissenschaftskommunikation.
Domasch, S. and Tannert, C.
Zeitschrift fuer Humanontogenetik 6
: 82-83.
1 January 2003
Retained functional normal and preleukemic HSCs at diagnosis are associated to good prognosis in DNMT3Amut NPM1mut AMLs.
Donato, E., Correia, N.C., Andresen, C., Karpova, D., Würth, R., Klein, C., Sohn, M., Przybylla, A., Zeisberger, P., Rothfelder, K., Salih, H.R., Bonig, H., Stasik, S., Röllig, C., Dolnik, A., Bullinger, L., Buchholz, F., Thiede, C.D., Hübschmann, D. and Trumpp, A.
Blood Advances 7
(6): 1011-1018.
28 March 2023
Loss of methylation at the IFNG promoter and CNS-1 associates with the development of functional IFN-γ memory in human CD4(+) T lymphocytes.
Dong, J., Chang, H.D., Ivascu, C., Qian, Y., Rezai, S., Okhrimenko, A., Cosmi, L., Maggi, L., Eckhardt, F., Wu, P., Sieper, J., Alexander, T., Annunziato, F., Gossen, M., Li, J., Radbruch, A. and Thiel, A.
European Journal of Immunology 43
(3): 793-804.
March 2013
N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness.
Dong, Hongliang, Zeng, Lili, Chen, Weiwei, Zhang, Qian, Wang, Fei, Wu, Yan, Cui, Bingjie, Qi, Jingjing, Zhang, Xin, Liu, Cuilan, Deng, Jiong, Yu, Y., Schmitt, C.A. and Du, Jing
Cell Death Discovery 9
(1): 149.
6 May 2023
Preimplantation development regulatory pathway construction through a text-mining approach.
Donnard, E., Barbosa-Silva, A., Guedes, R.L., Fernandes, G.R., Velloso, H., Kohn, M.J., Andrade-Navarro, M.A. and Ortega, J.M.
BMC Genomics 12
(Suppl 4): S3.
22 December 2011
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H., Pusch, F., Bei, Y., von Stebut, J., Ibáñez, G., Guillan, K., Imami, K., Gürgen, D., Rolff, J., Helmsauer, K., Meyer-Liesener, S., Timme, N., Bardinet, V., Chamorro González, R., MacArthur, I.C., Chen, C.Y., Schulz, J., Wengner, A.M., Furth, C., Lala, B., Eggert, A., Seifert, G., Hundsoerfer, P., Kirchner, M., Mertins, P., Selbach, M., Lissat, A., Dubois, F., Horst, D., Schulte, J.H., Spuler, S., You, D., Dela Cruz, F., Kung, A.L., Haase, K., Di Virgilio, M., Scheer, M., Ortiz, M.V. and Henssen, A.G.
Nature Communications 13
(1): 4297.
25 July 2022
Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M., Klinger, B., Mari, T., Toedling, J., Blanc, E., Messerschmidt, C., Nadler-Holly, M., Ziehm, M., Sieber, A., Hertwig, F., Beule, D., Eggert, A., Schulte, J.H., Selbach, M. and Blüthgen, N.
PLoS Computational Biology 17
(11): e1009515.
4 November 2021
MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.
Dorsett, Y., McBride, K.M., Jankovic, M., Gazumyan, A., Thai, T.H., Robbiani, D.F., Di Virgilio, M., Reina San-Martin, B., Heidkamp, G., Schwickert, T.A., Eisenreich, T., Rajewsky, K. and Nussenzweig, M.C.
Immunity 28
(5): 630-638.
16 May 2008
RP4 repressor protein KorB binds to the major groove of the operator DNA: A Raman study.
Dostal, L., Khare, D., Bok, J., Heinemann, U., Lanka, E. and Welfle, H.
Biochemistry 42
(49): 14476-14482.
1 January 2003
Raman spectroscopy of regulatory protein Omega from Streptococcus pyogenes plasmid pSM19035 and complexes with operator DNA.
Dostal, L., Misselwitz, R., Laettig, S., Alonso, J.C. and Welfle, H.
Spectroscopy 17
(2-3): 435-445.
2003
Binding of regulatory protein omega from Streptococcus pyogenes plasmid pSM19035 to direct and inverted 7-base pair repeats of operator DNA.
Dostal, L., Pratto, F., Alonso, J.C. and Welfle, H.
Journal of Raman Spectroscopy 38
(2): 166-175.
February 2007
Simultaneous imaging and flow-cytometry-based detection of multiple fluorescent senescence markers in therapy-induced senescent cancer cells.
Dovjak, E., Mairhofer, M., Wöß, C., Qi, J., Fan, D.N.Y., Schmitt, C.A. and Yu, Y.
Journal of Visualized Experiments
(185): e63973.
12 July 2022
Antitumor activity of Titanocene Y in xenografted PC3 tumors in mice.
Dowling, C.M., Claffey, J., Cuffe, S., Fichtner, I., Pampillon, C., Sweeney, N.J., Strohfeldt, K., Watson, R.W. and Tacke, M.
Letters in Drug Design & Discovery 5
(2): 141-144.
March 2008
From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic acid and db-cAMP in vitro differentiation model.
Drab, M., Haller, H., Bychkov, R., Erdmann, B., Lindschau, C., Haase, H., Morano, I., Luft, F.C. and Wobus, A.M.
FASEB Journal 11
(11): 905-915.
September 1997
CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
Drachsler, M., Kleber, S., Mateos, A., Volk, K., Mohr, N., Chen, S., Cirovic, B., Tuettenberg, J., Gieffers, C., Sykora, J., Wirtz, C.R., Mueller, W., Synowitz, M. and Martin-Villalba, A.
Cell Death & Disease 7
: e2209.
28 April 2016
T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3-bispecific single-chain antibody construct1.
Dreier, T., Baeuerle, P.A., Fichtner, I., Gruen, M., Schlereth, B., Lorenczewski, G., Kufer, P., Lutterbuese, R., Riethmueller, G., Gjorstrup, P. and Bargou, R.C.
Journal of Immunology 170
(8): 4397-4402.
15 April 2003
PET in colorectal cancer.
Dresel, S. and Schlag, P.M.
Recent Results in Cancer Research 170
: 109-124.
2008
Modeling Structure-Activity Relationship of AMPK Activation.
Drewe, J., Küsters, E., Hammann, F., Kreuter, M., Boss, P. and Schöning, V.
Molecules 26
(21): 6508.
1 November 2021
Deep learning for prediction of population health costs.
Drewe-Boss, P., Enders, D., Walker, J. and Ohler, U.
BMC Medical Informatics and Decision Making 22
(1): 32.
3 February 2022
omniCLIP: probabilistic identification of protein-RNA interactions from CLIP-seq data.
Drewe-Boss, P., Wessels, H.H. and Ohler, U.
Genome Biology 19
: 183.
1 November 2018
MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis.
Dreyling, M.H., Schrader, K., Fonatsch, C., Schlegelberger, B., Haase, D., Schoch, C., Ludwig, W.D., Loeffler, H., Buechner, T., Wormann, B., Hiddemann, W. and Bohlander, S.K.
Blood 91
(12): 4662-4667.
15 June 1998
HCMV-encoded chemokine receptor US28 employs multiple routes for internalization.
Droese, J., Mokros, T., Hermosilla, R., Schuelein, R., Lipp, M., Höpken, U.E. and Rehm, A.
Biochemical and Biophysical Research Communications 322
(1): 42-49.
10 September 2004
Orientation regulation of class-switch recombination in human B cells.
Du, L., Oksenych, V., Wan, H., Ye, X., Dong, J., Ye, A.Y., Abolhassani, H., Vlachiotis, S., Zhang, X., de la Rosa, K., Hammarström, L., van der Burg, M., Alt, F.W. and Pan-Hammarström, Q.
Journal of Immunology 213
(8): 1093-1104.
15 October 2024
Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J., Neuenschwander, M., Yu, Y., Däbritz, J.H.M., Neuendorff, N.R., Schleich, K., Bittner, A., Milanovic, M., Beuster, G., Radetzki, S., Specker, E., Reimann, M., Rosenbauer, F., Mathas, S., Lohneis, P., Hummel, M., Dörken, B., von Kries, J.P., Lee, S. and Schmitt, C.A.
Blood 129
(1): 71-81.
5 January 2017
Generation of Epstein-Barr virus antigen-specific T cell receptors recognizing immunodominant epitopes of LMP1, LMP2A, and EBNA3C for immunotherapy.
Dudaniec, K., Westendorf, K., Nössner, E. and Uckert, W.
Human Gene Therapy 32
(17-18): 919-935.
21 September 2021
Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomography.
Dudkina, N.V., Kudryashev, M., Stahlberg, H. and Boekema, E.J.
Proceedings of the National Academy of Sciences of the United States of America 108
(37): 15196-15200.
13 September 2011
Limited relevance of the CHEK2 gene in hereditary breast cancer.
Dufault, M.R., Betz, B., Wappenschmidt, B., Hofmann, W., Bandick, K., Golla, A., Pietschmann, A., Nestle-Kraemling, C., Rhiem, K., Huettner, C., von Lindern, C., Dall, P., Kiechle, M., Untch, M., Jonat, W., Meindl, A., Scherneck, S., Niederacher, D., Schmutzler, R.K. and Arnold, N.
International Journal of Cancer 110
(3): 320-325.
1 January 2004
Epigenomic profiling of human CD4(+) T cells supports a linear differentiation model and highlights molecular regulators of memory development.
Durek, P., Nordström, K., Gasparoni, G., Salhab, A., Kressler, C., de Almeida, M., Bassler, K., Ulas, T., Schmidt, F., Xiong, J., Glažar, P., Klironomos, F., Sinha, A., Kinkley, S., Yang, X., Arrigoni, L., Amirabad, A.., Ardakani, F.B., Feuerbach, L., Gorka, O., Ebert, P., Müller, F., Li, N., Frischbutter, S., Schlickeiser, S., Cendon, C., Fröhler, S., Felder, B., Gasparoni, N., Imbusch, C.D., Hutter, B., Zipprich, G., Tauchmann, Y., Reinke, S., Wassilew, G., Hoffmann, U., Richter, A.S., Sieverling, L., Chang, H.D., Syrbe, U., Kalus, U., Eils, J., Brors, B., Manke, T., Ruland, J., Lengauer, T., Rajewsky, N., Chen, W., Dong, J., Sawitzki, B., Chung, H.R., Rosenstiel, P., Schulz, M.H., Schultze, J.L., Radbruch, A., Walter, J., Hamann, A. and Polansky, J.K.
Immunity 45
(5): 1148-1161.
15 November 2016
Functional classification of TP53 mutations in acute myeloid leukemia.
Dutta, S., Pregartner, G., Rücker, F.G., Heitzer, E., Zebisch, A., Bullinger, L., Berghold, A., Döhner, K. and Sill, H.
Cancers 12
(3): 637.
10 March 2020
Human promoters are intrinsically directional.
Duttke, S.H.C., Lacadie, S.A., Ibrahim, M.M., Glass, C.K., Corcoran, D.L., Benner, C., Heinz, S., Kadonaga, J.T. and Ohler, U.
Molecular Cell 57
(4): 674-684.
19 February 2015
Evaluation of aggression and fearfulness in domestic dog (Canis familiaris).
Dyjak, M., Boruta, A., Adamkiewicz, E., Walasek, A., Bury-Burzymski, P. and Lisowski, P.
Animal Science Papers and Reports 39
(4): 407-418.
2021
Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin.
Dyring-Andersen, B., Løvendorf, M.B., Coscia, F., Santos, A., Møller, L.B.P., Colaço, A.R., Niu, L., Bzorek, M., Doll, S., Andersen, J.L., Clark, R.A., Skov, L., Teunissen, M.B.M. and Mann, M.
Nature Communications 11
(1): 5587.
5 November 2020
Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.
Dzamukova, M., Brunner, T.M., Miotla-Zarebska, J., Heinrich, F., Brylka, L., Mashreghi, M.F., Kusumbe, A., Kühn, R., Schinke, T., Vincent, T.L.. and Löhning, M.
Nature Communications 13
(1): 3059.
1 June 2022
CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma.
Däbritz, J.H.M., Yu, Y., Milanovic, M., Schönlein, M., Rosenfeldt, M.T., Dörr, J.R., Kaufmann, A.M., Dörken, B. and Schmitt, C.A.
Molecular Cancer Therapeutics 15
(5): 1074-1081.
May 2016
Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care.
Döhner, H., Dolnik, A., Tang, L., Seymour, J.F., Minden, M.D., Stone, R.M., Del Castillo, T.B., Al-Ali, H.K., Santini, V., Vyas, P., Beach, C L., MacBeth, K.J., Skikne, B.S., Songer, S., Tu, N., Bullinger, L. and Dombret, H.
Leukemia 32
(12): 2546-2557.
December 2018
Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Kühn, M.W.M., Schroeder, T., Mayer, K., Lübbert, M., Wattad, M., Götze, K., Fransecky, L., Koller, E., Wulf, G., Schleicher, J., Ringhoffer, M., Greil, R., Hertenstein, B., Krauter, J., Martens, U.M., Nachbaur, D., Samra, M.A., Machherndl-Spandl, S., Basara, N., Leis, C., Schrade, A., Kapp-Schwoerer, S., Cocciardi, S., Bullinger, L., Thol, F., Heuser, M., Paschka, P., Gaidzik, V.I., Saadati, M., Benner, A., Schlenk, R.F., Döhner, K. and Ganser, A.
Lancet Haematology 10
(7): e495-e509.
July 2023
Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Wulf, G.G., Salih, H.R., Lübbert, M., Kühn, M., Schroeder, T., Salwender, H., Götze, K.S., Westermann, J., Fransecky, L., Mayer, K., Hertenstein, B., Ringhoffer, M., Tischler, H.J., Machherndl-Spandl, S., Schrade, A., Paschka, P., Gaidzik, V.I., Theis, F., Thol, F.R., Heuser, M., Schlenk, R.F., Bullinger, L., Saadati, M., Benner, A., Larson, R.A., Stone, R.M., Döhner, K. and Ganser, A.
Blood Advances 6
(18): 5345-5355.
27 September 2022
Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Dönig, J., Mende, H., Davila Gallesio, J., Wagner, K., Hotz, P., Schunck, K., Piller, T., Hölper, S., Uhan, S., Kaulich, M., Wirth, M., Keller, U., Tascher, G., Bohnsack, K.E. and Müller, S.
Nature Communications 14
(1): 8121.
8 December 2023
Longtime outcome after intraosseous application of autologous mesenchymal stromal cells in pediatric patients and young adults with avascular necrosis after steroid or chemotherapy.
Döring, M., Kluba, T., Cabanillas Stanchi, K.M., Kahle, P., Lenglinger, K., Tsiflikas, I., Treuner, C., Vaegler, M., Mezger, M., Erbacher, A., Schumm, M., Lang, P., Handgretinger, R. and Müller, I.
Stem Cells and Development 29
(13): 811-822.
July 2020
Effective symptom relief through continuous integration of palliative care in advanced renal cell carcinoma patients: comprehensive measurement using the palliative care base assessment.
Dörr, A., Vogel, I., Wittenbecher, F., Westermann, J., Thuss-Patience, P., Ahn, J., Pelzer, U., Hardt, J., Bullinger, L. and Flörcken, A.
Palliative Care and Social Practice 18
: 26323524241260424.
24 June 2024
Thrombus or tumor? A case report of a rare sarcoma entity: intimal sarcoma of the pulmonary arteries.
Dörr, A., Flörcken, A, Bullinger, L., Capper, D., Von Deimling, A., Kaul, D., Märdian, S., Starck, C., Horst, D., Dragomir, M.P., Schäfer, F.M. and Jarosch, A.
Molecular Biology Reports 51
: 568.
24 April 2024
C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages.
Dörr, D., Obermayer, B., Weiner, J.M., Zimmermann, K., Anania, C., Wagner, L.K., Lyras, E.M., Sapozhnikova, V., Lara-Astiaso, D., Prósper, F., Lang, R., Lupiáñez, D.G., Beule, D., Höpken, U.E., Leutz, A. and Mildner, A.
Science Immunology 7
(75): eabj0140.
September 2022
Germline mutations including the rare pathogenic variant c.3206delC in the ATM gene cause ataxia teleangiectasia-associated primary central nervous system lymphoma.
Dörr, J.R., Thorwarth, A., Mizia-Malarz, A., Radke, J., Tietze, A., Hernáiz-Driever, P., Horn, D., Gratopp, A., Eggert, A. and Deubzer, H.E.
Children 8
(6): 469.
June 2021
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr, J.R., Yu, Y., Milanovic, M., Beuster, G., Zasada, C., Däbritz, J.H.M., Lisec, J., Lenze, D., Gerhardt, A., Schleicher, K., Kratzat, S., Purfürst, B., Walenta, S., Mueller-Klieser, W., Gräler, M., Hummel, M., Keller, U., Buck, A.K., Dörken, B., Willmitzer, L., Reimann, M., Kempa, S., Lee, S. and Schmitt, C.A.
Nature 501
(7467): 421-425.
19 September 2013
MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy.
Dössinger, G., Bunse, M., Bet, J., Albrecht, J., Paszkiewicz, P.J., Weißbrich, B., Schiedewitz, I., Henkel, L., Schiemann, M., Neuenhahn, M., Uckert, W. and Busch, D.H.
PLoS ONE 8
(4): e61384.
26 April 2013
Detection of Bombali virus in a Mops condylurus bat in Kyela, Tanzania.
Düx, A., Lwitiho, S.E., Ayouba, A., Röthemeier, C., Merkel, K., Weiss, S., Thaurignac, G., Lander, A., Kouadio, L., Nowak, K., Corman, V., Drosten, C., Couacy-Hymann, E., Krüger, D.H., Kurth, A., Calvignac-Spencer, S., Peeters, M., Ntinginya, N.E., Leendertz, F.H. and Mangu, C.
Viruses 16
(8): 1227.
August 2024
Quantitative imaging of gut microbiota spatial organization.
Earle, K.A., Billings, G., Sigal, M., Lichtman, J.S., Hansson, G.C., Elias, J.E., Amieva, M.R., Huang, K.C. and Sonnenburg, J.L.
Cell Host & Microbe 18
(4): 478-488.
14 October 2015
Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families.
Easton, D., Bishop, D.T., Ford, D., Crockford, G.P., Scherneck, S. and Zimmerman, W.
American Journal of Human Genetics 52
(4): 678-701.
April 1993
Spatial transcriptomics of C. elegans males and hermaphrodites identifies sex-specific differences in gene expression patterns.
Ebbing, A., Vértesy, Á., Betist, M.C., Spanjaard, B., Junker, J.P., Berezikov, E., van Oudenaarden, A. and Korswagen, H.C.
Developmental Cell 47
(6): 801-813.
17 December 2018
Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T(H)2-biased immunization.
Ebenig, A., Muraleedharan, S., Kazmierski, J., Todt, D., Auste, A., Anzaghe, M., Gömer, A., Postmus, D., Gogesch, P., Niles, M., Plesker, R., Miskey, C., Gellhorn Serra, M., Breithaupt, A., Hörner, C., Kruip, C., Ehmann, R., Ivics, Z., Waibler, Z., Pfaender, S., Wyler, E., Landthaler, M., Kupke, A., Nouailles, G., Goffinet, C., Brown, R.J.P and Mühlebach, M.D.
Cell Reports 40
(7): 111214.
16 August 2022
CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants.
Eberle, J., Fecker, L.F., Hossini, A.M., Wieder, T., Daniel, P.T., Orfanos, C.E. and Geilen, C.C.
Oncogene 22
(57): 9131-9141.
11 December 2003
Haplotype-resolved diverse human genomes and integrated analysis of structural variation.
Ebert, P., Audano, P. A., Zhu, Q., Rodriguez-Martin, B., Porubsky, D., Bonder, M.J., Sulovari, A., Ebler, J., Zhou, W., Serra Mari, R., Yilmaz, F., Zhao, X., Hsieh, P.H., Lee, J., Kumar, S., Lin, J., Rausch, T., Chen, Y., Ren, J., Santamarina, M., Höps, W., Ashraf, H., Chuang, N.T., Yang, X., Munson, K.M., Lewis, A.P., Fairley, S., Tallon, L.J., Clarke, W.E., Basile, A.O., Byrska-Bishop, M., Corvelo, A., Evani, U.S., Lu, T.Y., Chaisson, M.J.P., Chen, J., Li, C., Brand, H., Wenger, A.M., Ghareghani, M., Harvey, W.T., Raeder, B., Hasenfeld, P., Regier, A.A., Abel, H.J., Hall, I.M., Flicek, P., Stegle, O., Gerstein, M.B, Tubio, J.M.C., Mu, Z., Li, Y.I., Shi, X., Hastie, A.R., Ye, K., Chong, Z., Sanders, A.D., Zody, M.C., Talkowski, M.E., Mills, R. E., Devine, S.E., Lee, C., Korbel, J.O., Marschall, T. and Eichler, E.E.
Science 372
(6537): eabf7117.
25 February 2021
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Ebralidze, A.K., Guibal, F.C., Steidl, U., Zhang, P., Lee, S., Bartholdy, B., Jorda, M.A., Petkova, V., Rosenbauer, F., Huang, G., Dayaram, T., Klupp, J., O'Brien, K.B., Will, B., Hoogenkamp, M., Borden, K.L., Bonifer, C. and Tenen, D.G.
Genes & Development 22
(15): 2085-2092.
1 August 2008
Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes.
Ebstein, F., Textoris-Taube, K., Keller, C., Golnik, R., Vigneron, N., Van den Eynde, B.J., Schuler-Thurner, B., Schadendorf, D., Lorenz, F.K.M., Uckert, W., Urban, S., Lehmann, A., Albrecht-Koepke, N., Janek, K., Henklein, P., Niewienda, A., Kloetzel, P.M. and Mishto, M.
Scientific Reports 6
: 24032.
6 April 2016
Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L., Czajkowski, M.T., Barth, C., Müller, P.M., McShane, E., Grunwald, S., Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G., Selbach, M., Hammes, A., Daumke, O., Klussmann, E., Urbé, S. and Rocks, O.
Nature Communications 7
: 12963.
7 October 2016
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Ecker, J., Oehme, I., Mazitschek, R., Korshunov, A., Kool, M., Hielscher, T., Kiss, J., Selt, F., Konrad, C., Lodrini, M., Deubzer, H.E., von Deimling, A., Kulozik, A.E., Pfister, S.M., Witt, O. and Milde, T.
Acta Neuropathologica Communications 3
: 22.
3 April 2015
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts.
Eckert, M.A., Coscia, F., Chryplewicz, A., Chang, J.W., Hernandez, K.M., Pan, S., Tienda, S.M., Nahotko, D.A., Li, G., Blaženović, I., Lastra, R.R., Curtis, M., Yamada, S.D., Perets, R., McGregor, S.M., Andrade, J., Fiehn, O., Moellering, R.E., Mann, M. and Lengyel, E.
Nature 569
(7758): 723-728.
30 May 2019
Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Edelmann, J., Holzmann, K., Tausch, E., Saunderson, E.A., Jebaraj, B.M.C., Steinbrecher, D., Dolnik, A., Blätte, T.J., Landau, D.A., Saub, J., Estenfelder, S., Ibach, S., Cymbalista, F., Leblond, V., Delmer, A., Bahlo, J., Robrecht, S., Fischer, K., Goede, V., Bullinger, L., Wu, C.J., Mertens, D., Ficz, G., Gribben, J.G., Hallek, M., Döhner, H. and Stilgenbauer, S.
Haematologica 105
(5): 1379-1390.
May 2020
TCR and CAR engineering of primary human T cells.
Edes, I., Clauss, J., Stahn, R., Sada Japp, A. and Lorenz, F.K.M.
Methods in Molecular Biology 2521
(3): 85-93.
23 June 2022
Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma.
Edginton-White, B., Cauchy, P., Assi, S.A., Hartmann, S., Riggs, A.G., Mathas, S., Cockerill, P.N. and Bonifer, C.
Leukemia 33
(6): 1463-1474.
June 2019
Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial.
Eich, H.T., Diehl, V., Goergens, H., Pabst, T., Markova, J., Debus, J., Ho, A., Doerken, B., Rank, A., Grosu, A.L., Wiegel, T., Karstens, J.H., Greil, R., Willich, N., Schmidberger, H., Doehner, H., Borchmann, P., Mueller-Hermelink, H.K., Mueller, R.P. and Engert, A.
Journal of Clinical Oncology 28
(27): 4199-4206.
20 September 2010
Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
Eichenauer, D.A., Plütschow, A., Kreissl, S., Sökler, M., Hellmuth, J.C., Meissner, J., Mathas, S., Topp, M.S., Behringer, K., Klapper, W., Kuhnert, G., Dietlein, M., Kobe, C., Fuchs, M., Diehl, V., Engert, A. and Borchmann, P.
Lancet Oncology 18
(12): 1680-1687.
December 2017
Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL - long-term follow-up from the prospective ALL-SCT 2003 trial.
Eichinger, A., Poetschger, U., Glogova, E., Bader, P., Basu, O., Beier, R., Burkhardt, B., Classen, C.F., Claviez, A., Corbacioglu, S., Deubzer, H.E., Greil, J., Gruhn, B., Güngör, T., Kafa, K., Kühl, J.S., Lang, P., Lange, B.S., Meisel, R., Müller, I., Sauer, M.G., Schlegel, P.G., Schulz, A., Stachel, D., Strahm, B., Wawer, A., Peters, C. and Albert, M.H.
Leukemia 36
(11): 2567-2576.
November 2022
In colon epithelia, Clostridium perfringens enterotoxin causes focal leaks by targeting claudins which are apically accessible due to tight junction derangement.
Eichner, M., Augustin, C., Fromm, A., Piontek, A., Walther, W., Buecker, R., Fromm, M., Krause, G., Schulzke, J.D., Guenzel, D. and Piontek, J.
Journal of Infectious Diseases 217
(1): 147-157.
27 December 2017
Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert, T., Hsu, C.J., Becker, A.L., Graessle, S., Horne, A., Bemmann, F., Zhang, Q., Heuser, M., Vasioukhin, V., Scholl, S., Hochhaus, A., Siegerist, F., Endlich, N., Bullinger, L., Lane, S.W., Haas, S., Schnoeder, T.M and Heidel, F.H.
Leukemia 37
(10): 2027-2035.
October 2023
ASHLEYS: automated quality control for single-cell Strand-seq data.
Eimer, C., Sanders, A.D., Korbel, J.O., Marschall, T. and Ebert, P.
Bioinformatics 37
(19): 3356-3357.
1 October 2021
Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak and augments drug response.
Einsele-Scholz, S., Malmsheimer, S., Bertram, K., Stehle, D., Johaenning, J., Manz, M., Daniel, P.T., Gillissen, B.F., Schulze-Osthoff, K. and Essmann, F.
Journal of Cell Science 129
(11): 2213-2223.
1 June 2016
Histone deacetylase inhibitors have antitumor activity in two NOD/SCID mouse models of B-cell precursor childhood acute lymphoblastic leukemia.
Einsiedel, H.G., Kawan, L., Eckert, C., Witt, O., Fichtner, I., Henze, G. and Seeger, K.
Leukemia 20
(8): 1435-1436.
August 2006
Hepatoprotection in bile duct ligated mice mediated by darbepoetin-α is not caused by changes in hepatobiliary transporter expression.
Eipel, C., Menschikow, E., Sigal, M., Kuhla, A., Abshagen, K. and Vollmar, B.
International Journal of Clinical and Experimental Pathology 6
(1): 80-90.
1 January 2013
13C isotopologue perturbation studies of Listeria monocytogenes carbon metabolism and its modulation by the virulence regulator PrfA.
Eisenreich, W., Slaghuis, J., Laupitz, R., Bussemer, J., Stritzker, J., Schwarz, C., Schwarz, R., Dandekar, T., Goebel, W. and Bacher, A.
Proceedings of the National Academy of Sciences of the United States of America 103
(7): 2040-2045.
14 February 2006
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation.
Eitler, J., Rackwitz, W., Wotschel, N., Gudipati, V., Murali Shankar, N., Sidorenkova, A., Huppa, J.B., Ortiz-Montero, P., Opitz, C., Künzel, S.R., Michen, S., Temme, A., Loureiro, L.R., Feldmann, A., Bachmann, M., Boissel, L., Klingemann, H., Wels, W.S. and Tonn, T.
Journal for ImmunoTherapy of Cancer 12
(2): e008155.
27 February 2024
Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells.
Ekland, E.H., Forster, R., Lipp, M. and Cyster, J.G.
Journal of Immunology 172
(8): 4700-4708.
15 April 2004
The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
El-Athman, R., Genov, N.N., Mazuch, J., Zhang, K., Yu, Y., Fuhr, L., Abreu, M., Li, Y., Wallach, T., Kramer, A., Schmitt, C.A. and Relógio, A.
PLoS Biology 15
(12): e2002940.
7 December 2017
12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells.
El-Shemerly, M.Y., Besser, D., Nagasawa, M. and Nagamine, Y.
Journal of Biological Chemistry 272
(49): 30599-30602.
5 December 1997
Sugar metabolism of the first thermophilic planctomycete thermogutta terrifontis: comparative genomic and transcriptomic approaches.
Elcheninov, A.G., Menzel, P., Gudbergsdottir, S.R., Slesarev, A.I., Kadnikov, V.V., Krogh, A., Bonch-Osmolovskaya, E.A., Peng, X. and Kublanov, I.V.
Frontiers in Microbiology 8
: 2140.
2 November 2017
Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinases-1 in the liver: efficient protection against T-cell lymphoma and colon carcinoma metastasis.
Elezkurtaj, S., Kopitz, C., Baker, A.H., Perez-Canto, A., Arlt, M.J., Khokha, R., Gansbacher, B., Anton, M., Brand, K. and Krueger, A.
Journal of Gene Medicine 6
(11): 1228-1237.
23 September 2004
IkappaBalpha is required for marginal zone B cell lineage development.
Ellinghaus, U., Rupec, R.A., Pabst, O., Ignatius, R., Foerster, R., Doerken, B. and Jundt, F.
European Journal of Immunology 38
(8): 2096-2105.
August 2008
An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils.
Ellson, C.D., Goretti Riça, I., Kim, J.S., Huang, Y.M.M., Lim, D., Mitra, T., Hsu, A., Wei, E.X., Barrett, C.D., Otterbein, L.E., Hauser, C.J., Wahl, M., Delbrück, H., Heinemann, U., Oschkinat, H., Chang, C.E.A. and Yaffe, M.B.
Journal of Molecular Biology 434
(9): 167533.
15 May 2022
Mobile phones and health: Media coverage study of German newspapers on possible adverse health effects of mobile phone use.
Elvers, H.D., Jandrig, B., Grummich, K. and Tannert, C.
Health, Risk & Society 11
(2): 165-179.
April 2009
Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells.
Emmerich, F., Theurich, S., Hummel, M., Haeffker, A., Vry, M.S., Doehner, K., Bommert, K., Stein, H. and Doerken, B.
Journal of Pathology 201
(3): 413-420.
November 2003
Detection of tumor-specific mRNA in cell-free bronchial lavage supernatant in patients with lung cancer.
Engel, E., Schmidt, B., Carstensen, T., Weickmann, S., Jandrig, B., Witt, C. and Fleischhacker, M.
Annals of the New York Academy of Sciences 1022
: 140-146.
1 June 2004
Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif.
Engel, K., Schultz, H., Martin, F., Kotlyarov, A., Plath, K., Hahn, M., Heinemann, U. and Gaestel, M.
Journal of Biological Chemistry 270
(45): 27213-27221.
10 November 1995
Structural domains required for channel function of the mouse transient receptor potential protein homologue TRP1beta.
Engelke, M., Friedrich, O., Budde, P., Schaefer, C., Niemann, U., Zitt, C., Juengling, E., Rocks, O., Lueckhoff, A. and Frey, J.
FEBS Letters 523
(1-3): 193-199.
17 July 2002
Unsupervised meta-analysis on diverse gene expression datasets allows insight into gene function and regulation.
Engelmann, J.C., Schwarz, R., Blenk, S., Friedrich, T., Seibel, P.N., Dandekar, T. and Mueller, T.
Bioinformatics and Biology Insights 2
: 265-280.
26 May 2008
Retroviral vectors for high-level transgene expression in T lymphocytes.
Engels, B., Cam, H., Schueler, T., Indraccolo, S., Gladow, M., Baum, C., Blankenstein, T. and Uckert, W.
Human Gene Therapy 14
(12): 1155-1168.
10 August 2003
Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes.
Engels, B., Noessner, E., Frankenberger, B., Blankenstein, T., Schendel, D.J. and Uckert, W.
Human Gene Therapy 16
(7): 799-810.
1 July 2005
The Golgi protein RCAS1 controls cell surface expression of tumor-associated O-linked glycan antigens.
Engelsberg, A., Hermosilla, R., Karsten, U., Schuelein, R., Doerken, B. and Rehm, A.
Journal of Biological Chemistry 278
(25): 22998-23007.
1 January 2003
The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Doehner, H., Duyvene' de Wit, T., Eichinger, S., Fibbe, W., Green, T., de Haas, F., Iolascon, A., Jaffredo, T., Rodeghiero, F., Salles, G. and Schuringa, J.J.
Haematologica 101
(2): 115-208.
February 2016
Escalated-dose BEACOPP in the treatment of patients with advanced-stage Hodgkin's lymphoma: 10 years of follow-up of the GHSG HD9 study.
Engert, A., Diehl, V., Franklin, J., Lohri, A., Doerken, B., Ludwig, W.D., Koch, P., Haenel, M., Pfreundschuh, M., Wilhelm, M., Truemper, L., Aulitzky, W.E., Bentz, M., Rummel, M., Sezer, O., Mueller-Hermelink, H.K., Hasenclever, D. and Loeffler, M.
Journal of Clinical Oncology 27
(27): 4548-4554.
20 September 2009
Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.
Engert, A., Haverkamp, H., Kobe, C., Markova, J., Renner, C., Ho, A., Zijlstra, J., Kral, Z., Fuchs, M., Hallek, M., Kanz, L., Doehner, H., Doerken, B., Engel, N., Topp, M., Klutmann, S., Amthauer, H., Bockisch, A., Kluge, R., Kratochwil, C., Schober, O., Greil, R., Andreesen, R., Kneba, M., Pfreundschuh, M., Stein, H., Eich, H.T., Mueller, R.P., Dietlein, M., Borchmann, P. and Diehl, V.
Lancet 379
(9828): 1791-1799.
12 May 2012
Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.
Engert, A., Pluetschow, A., Eich, H.T., Lohri, A., Doerken, B., Borchmann, P., Berger, B., Greil, R., Willborn, K.C., Wilhelm, M., Debus, J., Eble, M.J., Soekler, M., Ho, A., Rank, A., Ganser, A., Truemper, L., Bokemeyer, C., Kirchner, H., Schubert, J., Kral, Z., Fuchs, M., Mueller-Hermelink, H.K., Mueller, R.P. and Diehl, V.
New England Journal of Medicine 363
(7): 640-652.
12 August 2010
Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.
Englbrecht, C.C., Schoof, H. and Boehm, S.
BMC Genomics 5
(1): 39.
5 July 2004
CS-1, a novel c-kithi+ acute myeloid leukemia cell line with dendritic cell differentiation capacity and absent immunogenicity.
Erben, U., Thiel, E., Bittroff-Leben, A., Schoch, C., Fichtner, I., Durkop, H. and Notter, M.
International Journal of Cancer 105
(2): 232-240.
10 June 2003
MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer.
Erdem, M., Lee, K.H., Hardt, M., Regan, J.L., Kobelt, D., Walther, W., Mokrizkij, M., Regenbrecht, C. and Stein, U.
Cancers 16
(3): 604.
31 January 2024
Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.
Erdmann, S., Senkel, S., Arndt, T., Lucas, B., Lausen, J., Klein-Hitpass, L., Ryffel, G.U. and Thomas, H.
Biological Chemistry 388
(1): 91-106.
January 2007
Parallel in-depth analysis of repeat expansions in ataxia patients by long-read sequencing.
Erdmann, H., Schöberl, F., Giurgiu, M., Leal Silva, R.M., Scholz, V., Scharf, F., Wendlandt, M., Kleinle, S., Deschauer, M., Nübling, G., Heide, W., Babacan, S.S., Schneider, C., Neuhann, T., Hahn, K., Schoser, B., Holinski-Feder, E., Wolf, D.A. and Abicht, A.
Brain 146
(5): 1831-1843.
May 2023
Efficient generation of B lymphocytes by recognition of self-antigens.
Eschbach, C., Bach, M.P., Fidler, I., Pelanda, R., Köhler, F., Rajewsky, K. and Jumaa, H.
European Journal of Immunology 41
(8): 2397-2403.
August 2011
Base editing repairs an SGCA mutation in human primary muscle stem cells.
Escobar, H., Krause, A., Keiper, S., Kieshauer, J., Müthel, S., García de Paredes, M., Metzler, E., Kühn, R., Heyd, F. and Spuler, S.
JCI Insight 6
(10): e145994.
24 May 2021
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19.
Essex, M., Millet Pascual-Leone, B.L., Löber, U., Kuhring, M., Zhang, B., Brüning, U., Fritsche-Guenther, R., Krzanowski, M., Fiocca Vernengo, F., Brumhard, S., Röwekamp, I., Bielecka, A.A., Lesker, T.R., Wyler, E., Landthaler, M., Mantei, A., Meisel, C., Caesar, S., Thibeault, C., Corman, V.M., Marko, L., Suttorp, N., Strowig, T., Kurth, F., Sander, L.E., Li, Y., Kirwan, J.A., Forslund, S.K. and Opitz, B.
NPJ Biofilms and Microbiomes 10
(1): 66.
1 August 2024
Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis.
Essmann, F., Pohlmann, S., Gillissen, B., Daniel, P.T., Schulze-Osthoff, K. and Jaenicke, R.U.
Journal of Biological Chemistry 280
(44): 37169-37177.
4 November 2005
Stable conditional expression and effect of C/EBPβ-LIP in adipocytes using the pSLIK system.
Esteves, C.L., Kelly, V., Bégay, V., Lillico, S.G., Leutz, A., Seckl, J.R. and Chapman, K.
Journal of Molecular Endocrinology 51
(1): 91-98.
4 June 2013
Regulation of adipocyte 11beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) by CCAAT/enhancer-binding protein (C/EBP) beta isoforms, LIP and LAP.
Esteves, C.L., Kelly, V., Bégay, V., Man, T.Y., Morton, N.M., Leutz, A., Seckl, J.R. and Chapman, K.E.
PLoS ONE 7
(5): e37953.
25 May 2012
A balance between secreted inhibitors and edge sensing controls gastruloid self-organization.
Etoc, F., Metzger, J., Ruzo, A., Kirst, C., Yoney, A., Ozair, M.Z., Brivanlou, A.H. and Siggia, E.D.
Developmental Cell 39
(3): 302-315.
7 November 2016
Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information.
Ettrich, T.J., Schwerdel, D., Dolnik, A., Beuter, F., Blätte, T.J., Schmidt, S.A., Stanescu-Siegmund, N., Steinacker, J., Marienfeld, R., Kleger, A., Bullinger, L., Seufferlein, T. and Berger, A.W.
Scientific Reports 9
(1): 13261.
13 September 2019
Non-equilibrium steady states of stochastic processes with intermittent resetting.
Eule, S. and Metzger, J.J.
New Journal of Physics 18
(3): 033006.
March 2016
Predictors of lower exercise capacity in patients with cancer.
Evertz, R., Diehl, C., Gödde, K., Valentova, M., Garfias-Veitl, T., Overbeck, T.R., Braulke, F., Lena, A., Hadzibegovic, S., Bleckmann, A., Keller, U., Landmesser, U., König, A.O., Hasenfuss, G., Schuster, A., Anker, M.S. and von Haehling, S.
Scientific Reports 13
(1): 14861.
8 September 2023
Cardiovascular and metabolic determinants of quality of life in patients with cancer.
Evertz, R., Gödde, K., Diehl, C., Valentova, M., Garfias-Veitl, T., Braulke, F., Wulf, G.G., Overbeck, T.R., Bleckmann, A., König, A.O., Weinländer, P., Potthoff, S., Hadzibegovic, S., Lena, A., Keller, U., Landmesser, U., Schuster, A., Anker, M.S., Hasenfuß, G. and von Haehling, S.
ESC Heart Failure 10
(1): 167-176.
February 2023
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Exner, N., Treske, B., Paquet, D., Holmstroem, K., Schiesling, C., Gispert, S., Carballo-Carbajal, I., Berg, D., Hoepken, H.H., Gasser, T., Krueger, R., Winklhofer, K.F., Vogel, F., Reichert, A.S., Auburger, G., Kahle, P.J., Schmid, B. and Haass, C.
Journal of Neuroscience 27
(45): 12413-12418.
7 November 2007
Evidence for recombinant GRP78, CALR, PDIA3 and GPI as mediators of genetic instability in human CD34+ cells.
Fabarius, A., Samra, V., Drews, O., Mörz, H., Bierbaum, M., Darwich, A., Weiss, C., Brendel, S., Kleiner, H., Seifarth, W., Greffrath, W., Hofmann, W.K., Schmitt, C.A. and Popp, H.D.
Cancers 14
(12): 2883.
11 June 2022
CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.
Faber, K., Bullinger, L., Ragu, C., Garding, A., Mertens, D., Miller, C., Martin, D., Walcher, D., Döhner, K., Döhner, H., Claus, R., Plass, C., Sykes, S.M., Lane, S.W., Scholl, C. and Fröhling, S.
Journal of Clinical Investigation 123
(1): 299-314.
2 January 2013
The genomic landscape of core-binding factor acute myeloid leukemias.
Faber, Z.J., Chen, X., Gedman, A.L., Boggs, K., Cheng, J., Ma, J., Radtke, I., Chao, J.R., Walsh, M.P., Song, G., Andersson, A.K., Dang, J., Dong, L., Liu, Y., Huether, R., Cai, Z., Mulder, H., Wu, G., Edmonson, M., Rusch, M., Qu, C., Li, Y., Vadodaria, B., Wang, J., Hedlund, E., Cao, X., Yergeau, D., Nakitandwe, J., Pounds, S.B., Shurtleff, S., Fulton, R.S., Fulton, L.L., Easton, J., Parganas, E., Pui, C.H., Rubnitz, J.E., Ding, L., Mardis, E.R., Wilson, R.K., Gruber, T.A., Mullighan, C.G., Schlenk, R.F., Paschka, P., Döhner, K., Döhner, H., Bullinger, L., Zhang, J., Klco, J.M. and Downing, J.R.
Nature Genetics 48
(12): 1551-1556.
December 2016
Conformation of d (GGGATCCC) 2 in crystals and in solution studied by X-ray diffraction, Raman spectroscopy and molecular modelling.
Fabian, H., Hoelzer, W., Heinemann, U., Sklenar, H. and Welfle, H.
Nucleic Acids Research 21
(3): 569-576.
11 February 1993
GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.
Fabian, J., Lodrini, M., Oehme, I., Schier, M.C., Thole, T.M., Hielscher, T., Kopp-Schneider, A., Opitz, L., Capper, D., von Deimling, A., Wiegand, I., Milde, T., Mahlknecht, U., Westermann, F., Popanda, O., Roels, F., Hero, B., Berthold, F., Fischer, M., Kulozik, A.E., Witt, O. and Deubzer, H.E.
Cancer Research 74
(9): 2604-2616.
1 May 2014
MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Fabian, J., Opitz, D., Althoff, K., Lodrini, M., Hero, B., Volland, R., Beckers, A., de Preter, K., Decock, A., Patil, N., Abba, M., Kopp-Schneider, A., Astrahantseff, K., Wünschel, J., Pfeil, S., Ercu, M., Künkele, A., Hu, J., Thole, T., Schweizer, L., Mechtersheimer, G., Carter, D., Cheung, B.B., Popanda, O., von Deimling, A., Koster, J., Versteeg, R., Schwab, M., Marshall, G.M., Speleman, F., Erb, U., Zoeller, M., Allgayer, H., Simon, T., Fischer, M., Kulozik, A.E., Eggert, A., Witt, O., Schulte, J.H. and Deubzer, H.E.
Oncotarget 7
(41): 66344-66359.
11 October 2016
Crystal structure of nucleotide-free dynamin.
Faelber, K., Posor, Y., Gao, S., Held, M., Roske, Y., Schulze, D., Haucke, V., Noe, F. and Daumke, O.
Nature 477
(7366): 556-560.
29 September 2011
Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Faelber, K., Dietrich, L., Noel, J.K., Wollweber, F., Pfitzner, A.K., Mühleip, A., Sánchez, R., Kudryashev, M., Chiaruttini, N., Lilie, H., Schlegel, J., Rosenbaum, E., Hessenberger, M., Matthaeus, C., Kunz, S., von der Malsburg, A., Noé, F., Roux, A., van der Laan, M., Kühlbrandt, W. and Daumke, O.
Nature 571
(7765): 429-433.
18 July 2019
Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli, U.M., Ullrich, K., Stuehmer, T., Holien, T., Koechert, K., Holt, R.U., Bruland, O., Chatterjee, M., Nogai, H., Lenz, G., Shaughnessy, J.D., Mathas, S., Sundan, A., Bargou, R.C., Doerken, B., Borset, M. and Janz, M.
Oncogene 30
(28): 3198-3206.
14 July 2011
IL-33 expression is lower in current smokers at both transcriptomic and protein level.
Faiz, A., Mahbub, R.M., Boedijono, F.S., Tomassen, M.I., Kooistra, W., Timens, W., Nawijn, M., Hansbro, P.M., Johansen, M.D., Pouwels, S.D., Heijink, I.H., Massip, F., de Biase, M.S., Schwarz, R.F., Adcock, I.M., Chung, K.F., van der Does, A., Hiemstra, P.S., Goulaouic, H., Xing, H., Abdulai, R., de Rinaldis, E., Cunoosamy, D., Harel, S., Lederer, D., Nivens, M.C., Wark, P.A., Kerstjens, H.A.M., Hylkema, M.N., Brandsma, C.A. and van den Berge, M.
American Journal of Respiratory and Critical Care Medicine 208
(10): 1075-1087.
15 November 2023
DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution.
Falconer, E., Hills, M., Naumann, U., Poon, S.S.S., Chavez, E.A., Sanders, A.D., Zhao, Y., Hirst, M. and Lansdorp, P.M.
Nature Methods 9
(11): 1107-1112.
November 2012
Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: enhanced in vivo potency of encephalitogenic peptides.
Falk, K., Roetzschke, O., Santambrogio, L., Dorf, M.E., Brosnan, C. and Strominger, J.L.
Journal of Experimental Medicine 191
(4): 717-730.
21 February 2000
Pillars article: allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991. 351: 290-296.
Falk, K., Roetzschke, O., Stevanovic, S., Jung, G. and Rammensee, H.G.
Journal of Immunology 177
(5): 2741-2747.
1 September 2006
Genotoxic stress-induced senescence.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1896
: 93-105.
2019
Detecting markers of therapy-induced senescence in cancer cells.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1534
: 41-52.
2017
Age attenuates the T-type Ca(V) 3.2-RyR axis in vascular smooth muscle.
Fan, G., Kaßmann, M., Cui, Y., Matthaeus, C., Kunz, S., Zhong, C., Zhu, S., Xie, Yu, Tsvetkov, D., Daumke, O., Huang, Yu and Gollasch, M.
Aging Cell 19
(4): e13134.
April 2020
A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit via FRET in a binary system.
Fang, G.M., Chamiolo, J., Kankowski, S., Hövelmann, F., Friedrich, D., Löwer, A., Meier, J.C. and Seitz, O.
Chemical Science 9
(21): 4794-4800.
7 June 2018
A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis.
Fang, L., Zhu, Q., Neuenschwander, M., Specker, E., Wulf-Goldenberg, A., Weis, W.I., von Kries, J.P. and Birchmeier, W.
Cancer Research 76
(4): 891-901.
15 February 2016
Beta-catenin regulates P-cadherin expression in mammary basal epithelial cells.
Faraldo, M.M., Teuliere, J., Deugnier, M.A., Birchmeier, W., Huelsken, J., Thiery, J.P., Cano, A. and Glukhova, M.A.
FEBS Letters 581
(5): 831-836.
6 March 2007
Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets.
Farazi, T.A., Leonhardt, C.S., Mukherjee, N., Mihailovic, A., Li, S., Max, K.E.A., Meyer, C., Yamaji, M., Cekan, P., Jacobs, N.C., Gerstberger, S., Bognanni, C., Larsson, E., Ohler, U. and Tuschl, T.
RNA 20
(7): 1090-1102.
July 2014
Immunological memory: lessons from the past and a look to the future.
Farber, D.L., Netea, M.G., Radbruch, A., Rajewsky, K. and Zinkernagel, R.M.
Nature Reviews Immunology 16
(2): 124-128.
February 2016
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
Fasciani, I., Petragnano, F., Wang, Z., Edwards, R., Telugu, N., Pietrantoni, I., Zabel, U., Zauber, H., Grieben, M., Terzenidou, M.E., Di Gregorio, J., Pellegrini, C., Santini, S., Taddei, A.R., Pohl, B., Aringhieri, S., Carli, M., Aloisi, G., Marampon, F., Charlesworth, E., Roman, A., Diecke, S., Flati, V., Giorgi, F., Amicarelli, F., Tobin, A.B., Scarselli, M., Tokatlidis, K., Rossi, M., Lohse, M.J., Annibale, P. and Maggio, R.
PLoS Biology 22
(4): e3002582.
29 April 2024
Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination.
Fazal, S.V., Gomez-Sanchez, J.A., Wagstaff, L.J., Musner, N., Otto, G., Janz, M., Mirsky, R. and Jessen, K.R.
Journal of Neuroscience 37
(50): 12297-12313.
13 December 2017
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Fecher, C., Trovò, L., Müller, S.A., Snaidero, N., Wettmarshausen, J., Heink, S., Ortiz, O., Wagner, I., Kühn, R., Hartmann, J., Karl, R.M., Konnerth, A., Korn, T., Wurst, W., Merkler, D., Lichtenthaler, S.F., Perocchi, F. and Misgeld, T.
Nature Neuroscience 22
(10): 1731-1742.
October 2019
Loss of proapoptotic Bcl-2-related multidomain proteins in primary melanomas is associated with poor prognosis.
Fecker, L.F., Geilen, C.C., Tchernev, G., Trefzer, U., Assaf, C., Kurbanov, B.M., Schwarz, C., Daniel, P.T. and Eberle, J.
Journal of Investigative Dermatology 126
: 1366-1371.
June 2006
Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma.
Fehlker, M., Huska, M.R., Joens, T., Andrade-Navarro, M.A. and Kemmner, W.
BMC Cancer 14
(1): 64.
5 February 2014
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation.
Feinberg, M.W., Wara, A.K., Cao, Z., Lebedeva, M.A., Rosenbauer, F., Iwasaki, H., Hirai, H., Katz, J.P., Haspel, R., Gray, S., Akashi, K., Segre, J., Kaestner, K.H., Tenen, D.G. and Jain, M.K.
EMBO Journal 26
(18): 4138-4148.
19 September 2007
Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients.
Feldheim, J., Kessler, A.F., Schmitt, D., Wilczek, L., Linsenmann, T., Dahlmann, M., Monoranu, C.M., Ernestus, R.I., Hagemann, C. and Löhr, M.
OncoTargets and Therapy 11
: 8673-8684.
4 December 2018
Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients.
Fendler, A., Bauer, D., Busch, J., Jung, K., Wulf-Goldenberg, A., Kunz, S., Song, K., Myszczyszyn, A., Elezkurtaj, S., Erguen, B., Jung, S., Chen, W. and Birchmeier, W.
Nature Communications 11
(1): 929.
17 February 2020
Impact of individualized treatment on recovery from fatigue and return to work in survivors of advanced stage Hodgkin Lymphoma: results from the randomized international GHSG HD18 trial.
Ferdinandus, J., Müller, H., Damaschin, C., Jacob, A.S., Meissner, J., Krasniqi, F., Mey, U., Schöndube, D., Thiemer, J., Mathas, S., Zijlstra, J., Greil, R., Feuring-Buske, M., Markova, J., Rüffer, J.U., Kobe, C., Eich, H.T., Baues, C., Fuchs, M., Borchmann, P. and Behringer, K.
Annals of Oncology 35
(3): 276-284.
March 2024
Assessing evolutionary and developmental transcriptome dynamics in homologous cell types.
Feregrino, C. and Tschopp, P.
Developmental Dynamics 251
(9): 1472-1489.
September 2022
SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.
Fernández-Sáiz, V., Targosz, B.S., Lemeer, S., Eichner, R., Langer, C., Bullinger, L., Reiter, C., Slotta-Huspenina, J., Schroeder, S., Knorn, A.M., Kurutz, J., Peschel, C., Pagano, M., Kuster, B. and Bassermann, F.
Nature Cell Biology 15
(1): 72-81.
January 2013
SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin.
Ferone, G., Song, J.Y., Sutherland, K.D., Bhaskaran, R., Monkhorst, K., Lambooij, J.P., Proost, N., Gargiulo, G. and Berns, A.
Cancer Cell 30
(4): 519-532.
10 October 2016
Long-term efficacy, safety and neurotolerability of MATRix regimen followed by autologous transplant in primary CNS lymphoma: 7-year results of the IELSG32 randomized trial.
Ferreri, A.J.M., Cwynarski, K., Pulczynski, E., Fox, C.P., Schorb, E., Celico, C., Falautano, M., Nonis, A., La Rosée, P., Binder, M., Fabbri, A., Ilariucci, F., Krampera, M., Roth, Al., Hemmaway, C., Johnson, P.W., Linton, K.M., Pukrop, T., Gørløv, J.S., Balzarotti, M., Hess, G., Keller, U., Stilgenbauer, S., Panse, J., Tucci, A., Orsucci, L., Pisani, F., Zanni, M., Krause, S.W., Schmoll, H.J., Hertenstein, B., Rummel, M., Smith, J., Thurner, L., Cabras, G., Pennese, E., Ponzoni, M., Deckert, M., Politi, L.S., Finke, J., Ferranti, A., Cozens, K., Burger, E., Ielmini, N., Cavalli, F., Zucca, E. and Illerhaus, G.
Leukemia 36
(7): 1870-1878.
July 2022
Thioester and oxyester linkages in the ubiquitin system.
Ferri-Blazquez, A., Jarosch, E. and Sommer, T.
Methods in Molecular Biology 2602
: 3-18.
2023
In vivo identification of lymphocyte subsets exhibiting transcriptionally active NF-kappaB/Rel complexes.
Feuillard, J., Memet, S., Goudeau, B., Lilienbaum, A., Schmidt-Ullrich, R., Raphael, M. and Israel, A.
International Immunology 12
(5): 613-621.
May 2000
Haploinsufficiency of ETV6 and CDKN1B in patients with acute myeloid leukemia and complex karyotype.
Feurstein, S., Rücker, F.G., Bullinger, L., Hofmann, W., Manukjan, G., Göhring, G., Lehmann, U., Heuser, M., Ganser, A., Döhner, K., Schlegelberger, B. and Steinemann, D.
BMC Genomics 15
: 784.
11 September 2014
Telemedizinische Visionen.
Feussner, H., Ricke, J., Hufnagl, P. and Schlag, P.M.
Onkologe 9
(1): 48-51.
January 2003
Praeklinische Daten als Grundlage fuer die Konzeption klinischer Studien [Preclinical data as basis for the design of clinical studies].
Fichtner, I.
Onkologie 31
(Suppl. 2): 34-38.
May 2008
Antileukaemic activity of treosulfan in xenografted human acute lymphoblastic leukaemias (ALL).
Fichtner, I., Becker, M. and Baumgart, J.
European Journal of Cancer 39
(6): 801-807.
April 2003
Differential protein expression pattern in tamoxifen-sensitive and -resistant breast cancer xenografts.
Fichtner, I., Becker, M., Besada, V. and Castellanos-Serra, L.
International Journal of Clinical Pharmacology and Therapeutics 42
(11): 632-634.
November 2004
In vivo models for endocrine-dependent breast carcinomas: special considerations of clinical relevance.
Fichtner, I., Becker, M., Zeisig, R. and Sommer, A.
European Journal of Cancer 40
(6): 845-851.
April 2004
The antiangiogenic and antitumoral activity of titanocene Y* in vivo.
Fichtner, I., Behrens, D., Claffey, J., Deally, A., Gleeson, B., Patil, S., Weber, H. and Tacke, M.
Letters in Drug Design & Discovery 8
(4): 302-307.
May 2011
Antitumor activity of oxali-titanocene Y in xenografted CAKI-1 tumors in mice.
Fichtner, I., Behrens, D., Claffey, J., Gleeson, B., Hogan, M., Wallis, D., Weber, H. and Tacke, M.
Letters in Drug Design & Discovery 5
(8): 489-493.
December 2008
In vitro and in vivo investigations into the carbene silver acetate anticancer drug candidate SBC1.
Fichtner, I., Cinatl, J., Michaelis, M., Sanders, L.C., Hilger, R., Kennedy, B.N., Reynolds, A.L., Hackenberg, F., Lally, G., Quinn, S.J., McRae, I. and Tacke, M.
Letters in Drug Design & Discovery 9
(9): 815-822.
November 2012
Antitumor activity of vanadocene Y and its selenocyanate derivative in xenografted CAKI-1 tumors in mice.
Fichtner, I., Claffey, J., Deally, A., Gleeson, B., Hogan, M., Rivera Markelova, M., Mueller-Bunz, H., Weber, H. and Tacke, M.
Journal of Organometallic Chemistry 695
(8): 1175-1181.
15 April 2010
The experimental antitumor agents phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models.
Fichtner, I., Monks, A., Hose, C., Stevens, M.F. and Bradshaw, T.D.
Breast Cancer Research and Treatment 87
(1): 97-107.
1 September 2004
Chemo- and radiation sensitivity of xenografted acute lymphoblastic leukemias-correlation to the expression of multidrug resistance proteins.
Fichtner, I., Paal, K., Borgmann, A., Badiali, L., Wurm, R. and Henze, G.
Anticancer Research 23
(3): 2657-2664.
May 2003
Anti-tumor activity of Titanocene Y in xenografted Caki-1 tumors in mice.
Fichtner, I., Pampillon, C., Sweeney, N.J., Strohfeldt, K. and Tacke, M.
Anti-Cancer Drugs 17
(3): 333-336.
March 2006
In vivo characterization of immunogenicity of a mitoxantrone-resistant murine P388 leukemia.
Fichtner, I., Reipert, B., Becker, M. and Lemm, M.
In Vivo 7
(1): 73-80.
January 1993
Animal experiments - An essential component for the development of liposomal anticancer agents.
Fichtner, I., Reszka, R., Arndt, D. and Zeisig, R.
Journal of Liposome Research 13
(1): 9-15.
3 December 2003
Stimulation of hematopoiesis by carboplatin-liposomes.
Fichtner, I., Reszka, R., Becker, M., Lemm, M., Richter, J. and Rudolph, M.
Journal of Liposome Research 4
(1): 43-69.
March 1994
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.
Fichtner, I., Rolff, J., Soong, R., Hoffmann, J., Hammer, S., Sommer, A., Becker, M. and Merk, J.
Clinical Cancer Research 14
(20): 6456-6468.
15 October 2008
Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas.
Fichtner, I., Slisow, W., Gill, J., Becker, M., Elbe, B., Hillebrand, T. and Bibby, M.
European Journal of Cancer 40
(2): 298-307.
January 2004
Animal models for personalized treatment options.
Fichtner, I., Klinghammer, K., Behrens, D., Flechsig, S., Rolff, J., Becker, M., Wulf-Goldenberg, A., Stecklum, M., Rivera, M., Brzezicha, B., Jandrig, B. and Hoffmann, J.
International Journal of Clinical Pharmacology and Therapeutics 55
(8): 698-700.
August 2017
Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example.
Fingleton, B., Lange, K., Caldwell, B. and Bankaitis, K.V.
Clinical and Experimental Metastasis 34
(8): 443-447.
December 2017
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Finkin, S., Yuan, D., Stein, I., Taniguchi, K., Weber, A., Unger, K., Browning, J.L., Goossens, N., Nakagawa, S., Gunasekaran, G., Schwartz, M.E., Kobayashi, M., Kumada, H., Berger, M., Pappo, O., Rajewsky, K., Hoshida, Y., Karin, M., Heikenwalder, M., Ben-Neriah, Y. and Pikarsky, E.
Nature Immunology 16
(12): 1235-1244.
December 2015
The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Finley, D., Ulrich, H.D., Sommer, T. and Kaiser, P.
Genetics 192
(2): 319-360.
1 October 2012
The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling.
Finsen, A.V., Ueland, T., Sjaastad, I., Ranheim, T., Ahmed, M.S., Dahl, C.P., Askevold, E.T., Aakhus, S., Husberg, C., Fiane, A.E., Lipp, M., Gullestad, L., Christensen, G., Aukrust, P. and Yndestad, A.
PLoS ONE 9
(11): e112172.
14 November 2014
R-spondin-YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.
Fischer, A.S., Müllerke, S., Arnold, A., Heuberger, J., Berger, H., Lin, M., Mollenkopf, H.J., Wizenty, J., Horst, D., Tacke, F. and Sigal, M.
Journal of Clinical Investigation 132
(21): e151363.
1 November 2022
Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils.
Fischer, J., Walter, C., Tönges, A., Aleth, H., Costa Jordão, M.J., Leddin, M., Gröning, V., Erdmann, T., Lenz, G., Roth, J., Vogl, T., Prinz, M., Dugas, M., Jacobsen, I.D. and Rosenbauer, F.
Nature Immunology 20
(5): 546-558.
May 2019
Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC.
Fiskin, E., Lareau, C.A., Ludwig, L.S., Eraslan, G., Liu, F., Ring, A.M., Xavier, R.J. and Regev, A.
Nature Biotechnology 40
(3): 374-381.
March 2022
Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR).
Fitze, G., Appelt, H., Koenig, I.R., Goergens, H., Stein, U., Walther, W., Gossen, M., Schreiber, M., Ziegler, A., Roesner, D. and Schackert, H.K.
Human Molecular Genetics 12
(24): 3207-3214.
1 January 2003
The transcription factor Hey and nuclear lamins specify and maintain cell identity.
Flint Brodsly, N., Bitman-Lotan, E., Boico, O., Shafat, A., Monastirioti, M., Gessler, M., Delidakis, C., Rincon-Arano, H. and Orian, A.
eLife 8
: e44745.
16 July 2019
Long-lasting remission of pulmonary metastases of renal cell cancer under IFN-beta therapy in a patient with multiple sclerosis.
Floercken, A., Denecke, T., Kretzschmar, A., Gollasch, H., Reich, G. and Westermann, J.
Onkologie 29
: 382-384.
September 2006
Severe thrombocytopenia in a patient with metastatic renal cell carcinoma.
Floercken, A., Loew, A., Koch, M., Gebauer, B., Doerken, B. and Riess, H.
Onkologie 32
(11): 670-672.
November 2009
Hepatic arterial infusion chemotherapy for liver metastases from gastric cancer: an analysis in western patients.
Floercken, A., Schaefer, C., Bichev, D., Breithaupt, K., Dogan, Y., Schumacher, G., Gebauer, B., Riess, H., Doerken, B. and Thuss-Patience, P.C.
Tumori 97
(1): 19-24.
January 2011
Sorafenib, but not sunitinib, induces regulatory T cells in the peripheral blood of patients with metastatic renal cell carcinoma.
Floercken, A., Takvorian, A., Van Lessen, A., Singh, A., Hopfenmueller, W., Doerken, B., Pezzutto, A. and Westermann, J.
Anti-Cancer Drugs 23
(3): 298-302.
March 2012
DC generation from peripheral blood mononuclear cells in patients with chronic myeloid leukemia: Influence of interferons on DC yield and functional properties.
Floercken, A., Kopp, J., Kölsch, U., Meisel, C., Dörken, B., Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 12
(5): 1117-1123.
3 May 2016
Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken, A., Grau, M., Wolf, A., Weilemann, A., Kopp, J., Dörken, B., Blankenstein, T., Pezzutto, A., Lenz, P., Lenz, G. and Westermann, J.
International Journal of Cancer 136
(8): 1814-1826.
15 April 2015
Immunomodulatory molecules in renal cell cancer: CD80 and CD86 are expressed on tumor cells.
Flörcken, A., Johannsen, M., Nguyen-Hoai, T., Gerhardt, A., Miller, K., Dörken, B., Pezzutto, A., Westermann, J. and Jöhrens, K.
International Journal of Clinical and Experimental Pathology 10
(2): 1443-1454.
15 February 2017
Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study.
Flörcken, A., Kopp, J., van Lessen, A., Movassaghi, K., Takvorian, A., Jöhrens, K., Möbs, M., Schönemann, C., Sawitzki, B., Egerer, K., Dörken, B., Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9
(7): 1217-1227.
1 June 2013
Myeloid-derived suppressor cells in human peripheral blood: optimized quantification in healthy donors and patients with metastatic renal cell carcinoma.
Flörcken, A., Takvorian, A., Singh, A., Gerhardt, A., Ostendorf, B.N., Dörken, B., Pezzutto, A. and Westermann, J.
Immunology Letters 168
(2): 260-267.
December 2015
Anti-leukemia T cells in AML: TNF-α(+) CD8(+) T cells may escape detection and possibly reflect a stage of functional impairment.
Flörcken, A., van Lessen, A., Terwey, T.H., Dörken, B., Arnold, R., Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9
(7): 1200-1204.
1 June 2013
An autochthonous mouse model of Myd88- and BCL2-driven diffuse large B-cell lymphoma reveals actionable molecular vulnerabilities.
Flümann, R., Rehkämper, T., Nieper, P., Pfeiffer, P., Holzem, A., Klein, S., Bhatia, S., Kochanek, M., Kisis, I., Pelzer, B.W., Ahlert, H., Hauer, J., da Palma Guerreiro, A., Ryan, J.A., Reimann, M., Riabinska, A., Wiederstein, J., Krüger, M., Deckert, M., Altmüller, J., Klatt, A.R., Frenzel, L.P., Pasqualucci, L., Béguelin, W., Melnick, A.M., Sander, S., Montesinos-Rongen, M., Brunn, A., Lohneis, P., Büttner, R., Kashkar, H., Borkhardt, A., Letai, A., Persigehl, T., Peifer, M., Schmitt, C.A., Reinhardt, H.C. and Knittel, G.
Blood Cancer Discovery 2
(1): 70-91.
January 2021
Differentiation of cerebral neoplasms with vessel size imaging (VSI).
Foda, A., Kellner, E., Gunawardana, A., Gao, X., Janz, M., Kufner, A., Khalil, A.A., Geran, R., Mekle, R., Fiebach, J.B. and Galinovic, I.
Clinical Neuroradiology 32
(1): 239-248.
March 2022
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen.
Foerster, R., Mattis, A., Kremmer, E., Wolf, E., Brem, G. and Lipp, M.
Cell 87
(6): 1037-1047.
13 December 1996
CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.
Foerster, R., Schubel, A., Breitfeld, D., Kremmer, E., Renner-Mueller, I., Wolf, E. and Lipp, M.
Cell 99
(1): 23-33.
1 October 1999
Abnormal expression of the b cell homing chemokine receptor blr1 during the progression of acquired immunodeficiency syndrome.
Foerster, R., Schweigard, G., Johann, S., Emrich, T., Kremmer, E., Nerl, C. and Lipp, M.
Blood 90
(2): 520-525.
15 July 1997
THBS4, a novel stromal molecule of diffuse-type gastric adenocarcinomas, identified by transcriptome-wide expression profiling.
Foerster, S., Gretschel, S., Joens, T., Yashiro, M. and Kemmner, W.
Modern Pathology 24
(10): 1390-1403.
October 2011
T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia.
Fogli, L.K., Sundrud, M.S., Goel, S., Bajwa, S., Jensen, K., Derudder, E., Sun, A., Coffre, M., Uyttenhove, C., Van Snick, J., Schmidt-Supprian, M., Rao, A., Grunig, G., Durbin, J., Casola, S.S., Rajewsky, K. and Koralov, S.B.
Journal of Immunology 191
(6): 3100-3111.
15 September 2013
Assessment of curated phenotype mining in neuropsychiatric disorder literature.
Fontaine, J.F., Priller, J., Spruth, E., Perez-Iratxeta, C. and Andrade-Navarro, M.A.
Methods 74
: 90-96.
March 2015
L-glyceraldehyde inhibits neuroblastoma cell growth via a
multi-modal mechanism on metabolism and Signaling.
Forbes, M., Kempa, R., Mastrobuoni, G., Rayman, L., Pietzke, M., Bayram, S., Arlt, B., Spruessel, A., Deubzer, H.E. and Kempa, S.
Cancers 16
(9): 1664.
May 2024
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families.
Ford, D., Easton, D.F., Stratton, M., Narod, S., Goldgar, D., Devilee, P., Bishop, D.T., Weber, B., Lenoir, G., Chang-Claude, J., Sobol, H., Teare, M.D., Struewing, J., Arason, A., Scherneck, S., Peto, J., Rebbeck, T.R., Tonin, P., Neuhausen, S., Barkardottir, R., Eyfjord, J., Lynch, H., Ponder, B.A.J., Gayther, S.A., Birch, J.M., Lindblom, A., Stoppa-Lyonnet, D., Bignon, Y., Borg, A., Hamann, U., Haites, N., Scott, R.J., Maugard, C.M., Vasen, H., Seitz, S., Cannon-Albright, L.A., Schofield, A. and Zelada-Hedman, M.
American Journal of Human Genetics 62
(3): 676-689.
March 1998
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N., Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A., André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M., Cui, C., Daumke, O., Del Bel, K.L., Eibel, H., Feng, X., Franke, V., Gebhardt, J.C.M., Götz, A., Grunwald, S., Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M., Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W., Xiong, E., Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S., Rosenzweig, S.D., Schwarz, K., Turvey, S.E. and Wang, J.Y.
Science Immunology 8
(79): eade7953.
January 2023
PDBpaint, a visualization webservice to tag protein structures with sequence annotations.
Fournier, D. and Andrade-Navarro, M.A.
Bioinformatics 27
(18): 2605-2606.
15 September 2011
Functional and genomic analyses of α-solenoid proteins.
Fournier, D., Palidwor, G.A., Shcherbinin, S., Szengel, A., Schaefer, M.H., Perez-Iratxeta, C. and Andrade-Navarro, M.A.
PLoS ONE 8
(11): e79894.
21 November 2013
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Fox, R.G., Lytle, N.K., Jaquish, D.V., Park, F.D., Ito, T., Bajaj, J., Koechlein, C.S., Zimdahl, B., Yano, M., Kopp, J., Kritzik, M., Sicklick, J., Sander, M., Grandgenett, P.M., Hollingsworth, M.A., Shibata, S., Pizzo, D., Valasek, M., Sasik, R., Scadeng, M., Okano, H., Kim, Y., MacLeod, A.R., Lowy, A.M. and Reya, T.
Nature 534
(7607): 407-411.
16 June 2016
Integrated microfluidic platform for the electrochemical detection of breast cancer markers in patient serum samples.
Fragoso, A., Latta, D., Laboria, N., von Germar, F., Hansen-Hagge, T.E., Kemmner, W., Gaertner, C., Klemm, R., Drese, K.S. and O'Sullivan, C.K.
Lab on a Chip 11
(4): 625-631.
21 February 2011
Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms.
Francavilla, V., Accapezzato, D., De Salvo, M., Rawson, P., Cosimi, O., Lipp, M., Cerino, A., Cividini, A., Mondelli, M.U. and Barnaba, V.
European Journal of Immunology 34
(2): 427-437.
1 January 2004
Keratinocyte-specific ablation of protease-activated receptor-2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease.
Francis, N., Ayodele, B.A., O'Brien-Simpson, N.M., Birchmeier, W., Pike, R.N., Pagel, C.N. and Mackie, E.J.
Cellular Microbiology 20
(11): e12891.
November 2018
Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer.
Francy, C.A., Clinton, R.W., Froehlich, C., Murphy, C. and Mears, J.A.
Scientific Reports 7
(1): 10744.
6 September 2017
CD8-specific designed ankyrin repeat proteins improve selective gene delivery into human and primate T lymphocytes.
Frank, A.M., Weidner, T., Brynza, J., Uckert, W., Buchholz, C.J. and Hartmann, J.
Human Gene Therapy 31
(11-12): 679-691.
June 2020
Substrate binding favors enhanced NO binding to P450cam.
Franke, A., Stochel, G., Jung, C. and van Eldik, R.
Journal of the American Chemical Society 126
(13): 4181-4191.
1 January 2004
Identification of novel ubiquitous and cell type-specific factors that specifically recognize immunoglobulin heavy and light chain promoters.
Franke, S., Scholz, G. and Scheidereit, C.
Journal of Biological Chemistry 269
(31): 20075-20082.
5 August 1994
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Frankell, A.M., Dietzen, M., Al Bakir, M., Lim, E.L., Karasaki, T., Ward, S., Veeriah, S., Colliver, E., Huebner, A., Bunkum, A., Hill, M.S., Grigoriadis, K., Moore, D.A., Black, J.R.M., Liu, W.K., Thol, K., Pich, O., Watkins, T.B.K., Naceur-Lombardelli, C., Cook, D.E., Salgado, R., Wilson, G.A., Bailey, C., Angelova, M., Bentham, R., Martínez-Ruiz, C., Abbosh, C., Nicholson, A.G., Le Quesne, J., Biswas, D., Rosenthal, R., Puttick, C., Hessey, S., Lee, C., Prymas, P., Toncheva, A., Smith, J., Xing, W., Nicod, J., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Blyth, K.G., Fennell, D.A., Forster, M.D., Lee, S.M., Falzon, M., Hewish, M., Shackcloth, M.J., Lim, E., Benafif, S., Russell, P., Boleti, E., Krebs, M.G., Lester, J.F., Papadatos-Pastos, D., Ahmad, T., Thakrar, R.M., Lawrence, D., Navani, N., Janes, S.M., Dive, C., Blackhall, F.H, Summers, Y., Cave, J., Marafioti, T., Herrero, J., Quezada, S.A., Peggs, K.S., Schwarz, R.F., Van Loo, P., Miedema, D.M., Birkbak, N.J., Hiley, C.T., Hackshaw, A., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
(7957): 525-533.
20 April 2023
Influence of CD80, interleukin-2, and interleukin-7 expression in human renal cell carcinoma on the expansion, function, and survival of tumor-specific CTLs.
Frankenberger, B., Pohla, H., Noessner, E., Willimsky, G., Papier, B., Pezzutto, A., Kopp, J., Oberneder, R., Blankenstein, T. and Schendel, D.J.
Clinical Cancer Research 11
: 1733-1742.
1 January 2005
Cell-based vaccines for renal cell carcinoma: genetically-engineered tumor cells and monocyte-derived dendritic cells.
Frankenberger, B., Regn, S., Geiger, C., Noessner, E., Falk, C.S., Pohla, H., Javorovic, M., Silberzahn, T., Wilde, S., Buchner, A., Siebels, M., Oberneder, R., Willimsky, G., Pezzutto, A., Blankenstein, T. and Schendel, D.J.
World Journal of Urology 23
(3): 166-174.
5 July 2005
Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics.
Franz, A., Coscia, F., Shen, C., Charaoui, L., Mann, M. and Sander, C.
Journal of Ovarian Research 14
(1): 140.
22 October 2021
Circular RNAs in clear cell renal cell carcinoma: their microarray-based identification, analytical validation, and potential use in a clinico-genomic model to improve prognostic accuracy.
Franz, A., Ralla, B., Weickmann, S., Jung, M., Rochow, H., Stephan, C., Erbersdobler, A., Kilic, E., Fendler, A. and Jung, K.
Cancers 11
(10): 1473.
30 September 2019
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
Franz, A., Weber, A.I., Preußner, M., Dimos, N., Stumpf, A., Ji, Y., Moreno-Velasquez, L., Voigt, A., Schulz, F., Neumann, A., Kuropka, B., Kuehn, R., Urlaub, H., Schmitz, D., Wahl, M.C. and Heyd, F.
Life Science Alliance 6
(3): e202201826.
March 2023
MYB induces the expression of the oncogenic corepressor SKI in acute myeloid leukemia.
Frech, M., Teichler, S., Feld, C., Bouchard, C., Berberich, H., Sorg, K., Mernberger, M., Bullinger, L., Bauer, U.M. and Neubauer, A.
Oncotarget 9
(32): 22423-22435.
27 April 2018
CAR links hypoxia signaling to improved survival after myocardial infarction.
Freiberg, F., Thakkar, M., Hamann, W., Lopez Carballo, J., Jüttner, R., Voss, F.K., Becher, P.M., Westermann, D., Tschöpe, C., Heuser, A., Rocks, O., Fischer, R. and Gotthardt, M.
Experimental and Molecular Medicine 55
(3): 643-652.
March 2023
The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.
Frese, S., Schubert, W.D., Findeis, A.C., Marquardt, T., Roske, Y.S., Stradal, T.E. and Heinz, D.W.
Journal of Biological Chemistry 281
(26): 18236-18245.
30 June 2006
New insights into the biology of molecular subtypes of diffuse large B-cell lymphoma and Burkitt lymphoma.
Frick, M., Doerken, B. and Lenz, G.
Best Practice and Research Clinical Haematology 25
(1): 3-12.
March 2012
Role of donor clonal hematopoiesis in allogeneic hematopoietic stem-cell transplantation.
Frick, M., Chan, W., Arends, C.M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida, K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhäuser, M., Blau, I.W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E.M., Spriewald, B.M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socié, G., Kroeger, N., Bullinger, L., Thiede, C. and Damm, F.
Journal of Clinical Oncology 37
(5): 375-385.
10 February 2019
Nuclear localization signal and protein context both mediate importin α specificity of nuclear import substrates.
Friedrich, B., Quensel, C., Sommer, T., Hartmann, E. and Koehler, M.
Molecular and Cellular Biology 26
(23): 8697-8709.
December 2006
Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease.
Friedrich, V.D., Pennitz, P., Wyler, E., Adler, J.M., Postmus, D., Müller, K., Teixeira Alves, L.G., Prigann, J., Pott, F., Vladimirova, D., Hoefler, T., Goekeri, C., Landthaler, M., Goffinet, C., Saliba, A.E., Scholz, M., Witzenrath, M., Trimpert, J., Kirsten, H. and Nouailles, G.
EBioMedicine 108
: 105312.
October 2024
High expression level of alpha6 integrin in human breast carcinoma is correlated with reduced survival.
Friedrichs, K., Ruiz, P., Franke, F., Gille, I., Terpe, H.J. and Imhof, B.A.
Cancer Research 55
(4): 901-906.
15 February 1995
Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma.
Friesen, C., Hormann, I., Roscher, M., Fichtner, I., Alt, A., Hilger, R., Debatin, K.M. and Miltner, E.
Cell Cycle 13
(10): 1560-1570.
15 May 2014
Cell death sensitization of leukemia cells by opioid receptor activation.
Friesen, C., Roscher, M., Hormann, I., Fichtner, I., Alt, A., Hilger, R.A., Debatin, K.M. and Miltner, E.
Oncotarget 4
(5): 677-690.
16 April 2013
Therapeutic potential of CAMPATH-1H in skeletal tumours.
Fritsche-Guenther, R., Gruetzkau, A., Noske, A., Melcher, I., Schaser, K.D., Schlag, P.M., Kasper, H.U., Krenn, V. and Sers, C.
Histopathology 57
(6): 851-861.
December 2010
De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway.
Fritsche-Guenther, R., Noske, A., Ungethuem, U., Kuban, R.J., Schlag, P.M., Tunn, P.U., Karle, J., Krenn, V., Dietel, M. and Sers, C.
Histopathology 57
(6): 836-850.
December 2010
Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Fritsche-Guenther, R., Zasada, C., Mastrobuoni, G., Royla, N., Rainer, R., Roßner, F., Pietzke, M., Klipp, E., Sers, C. and Kempa, S.
Scientific Reports 8
(1): 9204.
15 June 2018
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J., Morkel, M., Besser, D., Budczies, J., Kosel, F., Brembeck, F.H., Stein, U., Fichtner, I., Schlag, P.M. and Birchmeier, W.
Gastroenterology 137
(11): 165-175.
July 2009
Einfluss einer praeoperativen (hyperthermen) Radiochemotherapie auf die manometrisch erfasste Analsphinkterfunktion beim lokal fortgeschrittenen Rektumkarzinom [Influence of preoperative (hyperthermic) radiochemotherapy on manometric anal sphincter function in locally advanced rectal cancer].
Fritzmann, J., Huenerbein, M., Slisow, W., Gellermann, J., Wust, P. and Rau, B.
Strahlentherapie und Onkologie 180
: 281-288.
1 May 2004
Association of an impaired GH‑IGF‑I axis with cardiac wasting in patients with advanced cancer.
Fröhlich, A.K., Porthun, J., Talha, K.M., Lena, A., Hadzibegovic, S., Wilkenshoff, U., Sonntag, F., Nikolski, A., Ramer, L.V., Zeller, T., Keller, U., Bullinger, L., Anker, S.D., Haverkamp, W., von Haehling, S., Doehner, W., Rauch, U., Skurk, C., Cleland, J.G.F., Butler, J., Coats, A.J.S., Landmesser, U., Karakas, M. and Anker, M.S.
Clinical Research in Cardiology
8 April 2024
(In Press)
Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein.
Fröhlich, C., Grabiger, S., Schwefel, D., Faelber, K., Rosenbaum, E., Mears, J., Rocks, O. and Daumke, O.
EMBO Journal 32
(9): 1280-1292.
2 May 2013
RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells.
Fu, R., Wellman, K., Baldwin, A., Rege, J., Walters, K., Hirsekorn, A., Riemondy, K., Rainey, W.E and Mukherjee, N.
RNA 27
(8): 933-945.
August 2021
The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.
Fuchs, U., Rehkamp, G., Haas, O.A., Slany, R., Konig, M., Bojesen, S., Bohle, R.M., Damm-Welk, C., Ludwig, W.D., Harbott, J. and Borkhardt, A.
Proceedings of the National Academy of Sciences of the United States of America 98
(15): 8756-8761.
17 July 2001
Follow-up of the GHSG HD16 trial of PET-guided treatment in early-stage favorable Hodgkin lymphoma.
Fuchs, M., Jacob, A.S., Kaul, H., Kobe, C., Kuhnert, G., Pabst, T., Greil, R., Bröckelmann, P.J., Topp, M.S., Just, M., Hertenstein, B., Soekler, M., Vogelhuber, M., Zijlstra, J.M., Keller, U.B., Krause, S.W., Dührsen, U., Meissner, J., Viardot, A., Eich, H.T., Baues, C., Diehl, V., Rosenwald, A., Buehnen, I., von Tresckow, B., Dietlein, M., Borchmann, P., Engert, A. and Eichenauer, D.A.
Leukemia 38
(1): 160-167.
January 2024
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S., Danßmann, C., Klironomos, F., Winkler, A., Fallmann, J., Kruetzfeldt, L.M., Szymansky, A., Naderi, J., Bernhart, S.H., Grunewald, L., Helmsauer, K., Rodriguez-Fos, E., Kirchner, M., Mertins, P., Astrahantseff, K., Suenkel, C., Toedling, J., Meggetto, F., Remke, M., Stadler, P.F., Hundsdoerfer, P., Deubzer, H.E., Künkele, A., Lang, P., Fuchs, J., Henssen, A.G., Eggert, A., Rajewsky, N., Hertwig, F. and Schulte, J.H.
Nature Communications 14
(1): 3936.
4 July 2023
Cellular fingerprints: a novel approach using large-scale cancer cell line data for the identification of potential anticancer agents.
Fuellbeck, M., Dunkel, M., Hossbach, J., Daniel, P.T. and Preissner, R.
Chemical Biology & Drug Design 74
(5): 439-448.
November 2009
Computer-assisted identification of small-molecule Bcl-2 modulators.
Fuellbeck, M., Gebhardt, N., Hossbach, J., Daniel, P.T. and Preissner, R.
Computational Biology and Chemistry 33
(6): 451-456.
December 2009
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice.
Funk, M.C., Gleixner, J.G., Heigwer, F., Vonficht, D., Valentini, E., Aydin, Z., Tonin, E., Del Prete, S., Mahara, S., Throm, Y., Hetzer, J., Heide, D., Stegle, O., Odom, D.T., Feldmann, A., Haas, S., Heikenwalder, M. and Boutros, M.
Developmental Cell 58
(24): 2914-2929.
18 December 2023
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.
Funk, N., Munz, M., Ott, T., Brockmann, K., Wenninger-Weinzierl, A., Kühn, R., Vogt-Weisenhorn, D., Giesert, F., Wurst, W., Gasser, T. and Biskup, S.
Scientific Reports 9
(1): 4515.
14 March 2019
Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.
Futreal, P.A., Cochran, C., Marks, J.R., Iglehart, J.D., Zimmerman, W., Barrett, J.C. and Wiseman, R.W.
Cancer Research 54
(7): 1791-1794.
1 April 1994
A multimodal platform for simultaneous T-cell imaging, defined activation, and mechanobiological characterization.
Fölser, M., Motsch, V., Platzer, R., Huppa, J.B. and Schütz, G.J.
Cells 10
(2): 235.
February 2021
c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells.
Gabryšová, L., Alvarez-Martinez, M., Luisier, R., Cox, L.S., Sodenkamp, J., Hosking, C., Pérez-Mazliah, D., Whicher, C., Kannan, Y., Potempa, K., Wu, X., Bhaw, L., Wende, H., Sieweke, M.H., Elgar, G., Wilson, M., Briscoe, J., Metzis, V., Langhorne, J., Luscombe, N.M. and O'Garra, A.
Nature Immunology 19
(5): 497-507.
May 2018
Rolle und Aufgaben der chirurgischen Onkologie im Rahmen molekular definierter Therapien [Role and function of surgical oncology in molecular defined therapy].
Gaedcke, J., Schlag, P.M. and Ghadimi, M.
Onkologe 19
(10): 858-862.
October 2013
CT-gesteuerte Resektion pulmonaler Metastasen [CT-guided resection of pulmonary metastases].
Gaffke, G., Stroszczynski, C., Rau, B., Liebeskind, U., Huenerbein, M., Bayraktar, S., Schlag, P.M. and Felix, R.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 177
: 877-883.
1 January 2005
Diagnostik von Duenndarmtumoren mit Hilfe des CT-Entreoklysma : Die CT - Sellink ausgewertet bei 63 Patienten.
Gaffke, G., Stroszczynski, C., Schlecht, I., Jost, D., Ludwig, W.D., Schlag, P.M. and Felix, R.
Roentgenpraxis 54
(6): 214-219.
2002
Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG).
Gaidzik, V.I., Schlenk, R.F., Paschka, P., Stölzle, A., Späth, D., Kuendgen, A., von Lilienfeld-Toal, M., Brugger, W., Derigs, H.G., Kremers, S., Greil, R., Raghavachar, A., Ringhoffer, M., Salih, H.R., Wattad, M., Kirchen, H.G., Runde, V., Heil, G., Petzer, A.L., Girschikofsky, M., Heuser, M., Kayser, S., Goehring, G., Teleanu, M.V., Schlegelberger, B., Ganser, A., Krauter, J., Bullinger, L., Döhner, H. and Döhner, K.
Blood 121
(23): 4769-77.
6 June 2013
RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features.
Gaidzik, V.I., Teleanu, V., Papaemmanuil, E., Weber, D., Paschka, P., Hahn, J., Wallrabenstein, T., Kolbinger, B., Köhne, C.H., Horst, H.A., Brossart, P., Held, G., Kündgen, A., Ringhoffer, M., Götze, K., Rummel, M., Gerstung, M., Campbell, P., Kraus, J.M., Kestler, H.A., Thol, F., Heuser, M., Schlegelberger, B., Ganser, A., Bullinger, L., Schlenk, R.F., Döhner, K. and Döhner, H.
Leukemia 30
(11): 2160-2168.
November 2016
DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia.
Gaidzik, V.I., Weber, D., Paschka, P., Kaumanns, A., Krieger, S., Corbacioglu, A., Krönke, J., Kapp-Schwoerer, S., Krämer, D., Horst, H.A., Schmidt-Wolf, I., Held, G., Kündgen, A., Ringhoffer, M., Götze, K., Kindler, T., Fiedler, W., Wattad, M., Schlenk, R.F., Bullinger, L., Teleanu, V., Schlegelberger, B., Thol, F., Heuser, M., Ganser, A., Döhner, H. and Döhner, K.
Leukemia 32
(1): 30-37.
January 2018
Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes.
Gainullina, A., Mogilenko, D.A., Huang, L.H., Todorov, H., Narang, V., Kim, K.W., Yng, L.S., Kent, A., Jia, B., Seddu, K., Krchma, K., Wu, J., Crozat, K., Tomasello, E., Dress, R., See, P., Scott, C., Gibbings, S., Bajpai, G., Desai, J.V., Maier, B., This, S., Wang, P., Aguilar, S.V., Poupel, L., Dussaud, S., Zhou, T.A., Angeli, V., Blander, J.M., Choi, K., Dalod, M., Dzhagalov, I., Gautier, E.L., Jakubzick, C., Lavine, K., Lionakis, M.S., Paidassi, H., Sieweke, M.H., Ginhoux, F., Guilliams, M., Benoist, C., Merad, M., Randolph, G.J., Sergushichev, A. and Artyomov, M.N.
Cell Reports 42
(2): 112046.
28 February 2023
Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.
Gaiser, O.J., Ball, L.J., Schmieder, P., Leitner, D., Strauss, H., Wahl, M., Kuehne, R., Oschkinat, H. and Heinemann, U.
Biochemistry 43
(51): 15983-15995.
1 January 2004
Structural basis for the substrate specificity of a Bacillus 1,3-1,4-beta-glucanase.
Gaiser, O.J., Piotukh, K., Ponnuswamy, W.N., Planas, A., Borriss, R. and Heinemann, U.
Journal of Molecular Biology 357
(4): 1211-1225.
7 April 2006
Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects.
Galgoczi, S., Ruzo, A., Markopoulos, C., Yoney, A., Phan-Everson, T., Li, S., Haremaki, T., Metzger, J.J., Etoc, F. and Brivanlou, A.H.
Development 148
(19): dev199513.
October 2021
Natural course of untreated microalbuminuria in children and adolescents with type 1 diabetes and the importance of diabetes duration and immigrant status: longitudinal analysis from the prospective nationwide German and Austrian diabetes survey DPV.
Galler, A., Haberland, H., Naeke, A., Hofer, S., Holder, M., Raile, K. and Holl, R.W.
European Journal of Endocrinology 166
(3): 493-501.
March 2012
Associations between media consumption habits, physical activity, socioeconomic status, and glycemic control in children, adolescents, and young adults with type 1 diabetes.
Galler, A., Lindau, M., Ernert, A., Thalemann, R. and Raile, K.
Diabetes Care 34
(11): 2356-2359.
November 2011
Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer.
Galling, N., Kobelt, D., Aumann, J., Schmidt, M., Wittig, B., Schlag, P.M. and Walther, W.
Human Gene Therapy Part B Methods 23
(4): 264-270.
August 2012
A conserved noncoding locus regulates random monoallelic Xist expression across a topological boundary.
Galupa, R., Nora, E.P., Worsley-Hunt, R., Picard, C., Gard, C., van Bemmel, J.G., Servant, N., Zhan, Y., El Marjou, F., Johanneau, C., Diabangouaya, P., Le Saux, A., Lameiras, S., Pipoli da Fonseca, J., Loos, F., Gribnau, J., Baulande, S., Ohler, U., Giorgetti, L. and Heard, E.
Molecular Cell 77
(2): 352-367.
16 January 2020
Landscape of HER2-low metastatic breast cancer (MBC): results from the Austrian AGMT_MBC-Registry.
Gampenrieder, S.P., Rinnerthaler, G., Tinchon, C., Petzer, A., Balic, M., Heibl, S., Schmitt, C., Zabernigg, A.F., Egle, D., Sandholzer, M., Singer, C.F., Roitner, F., Hager, C., Andel, J., Hubalek, M., Knauer, M. and Greil, R.
Breast Cancer Research 23
(1): 112.
14 December 2021
The Chriz-Z4 complex recruits JIL-1 to polytene chromosomes, a requirement for interband-specific phosphorylation of H3S10.
Gan, M., Moebus, S., Eggert, H. and Saumweber, H.
Journal of Biosciences 36
(3): 425-438.
August 2011
Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Ganichkin, O.M., Vancraenenbroeck, R., Rosenblum, G., Hofmann, H., Mikhailov, A.S., Daumke, O. and Noel, J.K.
Proceedings of the National Academy of Sciences of the United States of America 118
(28): e2101144118.
13 July 2021
Structure of myxovirus resistance protein A reveals intra- and intermolecular domain interactions required for the antiviral function.
Gao, S., von der Malsburg, A., Dick, A., Faelber, K., Schroeder, G.F., Haller, O., Kochs, G. and Daumke, O.
Immunity 35
(4): 514-525.
28 October 2011
Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao, S., von der Malsburg, A., Paeschke, S., Behlke, J., Haller, O., Kochs, G. and Daumke, O.
Nature 465
(7297): 502-506.
27 May 2010
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.
Garces de Los Fayos Alonso, I., Zujo, L., Wiest, I., Kodajova, P., Timelthaler, G., Edtmayer, S., Zrimšek, M., Kollmann, S., Giordano, C., Kothmayer, M., Neubauer, H.A., Dey, S., Schlederer, M., Schmalzbauer, B.S., Limberger, T., Probst, C., Pusch, O., Högler, S., Tangermann, S., Merkel, O., Schiefer, A.I., Kornauth, C., Prutsch, N., Zimmerman, M., Abraham, B., Anagnostopoulos, J., Quintanilla-Martinez, L., Mathas, S., Wolf, P., Stoiber, D., Staber, P.B., Egger, G., Klapper, W., Woessmann, W., Look, T.A., Gunning, P., Turner, S.D., Moriggl, R., Lagger, S. and Kenner, L.
Molecular Cancer 21
(1): 172.
31 August 2022
Positive and negative unintended human-induced effects on Iberian mole abundance at the edge of its distribution area.
García-López de Hierro, L., Moleón, M., Lupiáñez, D.G., Virgós, E. and Jiménez, R.
Mammalian Biology 78
(4): 276-282.
June 2013
A novel form of RNA double helix based on G·U and C·A(+) wobble base pairing.
Garg, A. and Heinemann, U.
RNA 24
(2): 209-218.
February 2018
PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Garg, A., Roske, Y., Yamada, S., Uehata, T., Takeuchi, O. and Heinemann, U.
Nucleic Acids Research 49
(9): 5369-5381.
21 May 2021
In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.
Gargiulo, G., Cesaroni, M., Serresi, M., de Vries, N., Hulsman, D., Bruggeman, S.W., Lancini, C. and van Lohuizen, M.
Cancer Cell 23
(5): 660-676.
13 May 2013
Polycomb and lung cancer: when the dosage makes the (kind of) poison.
Gargiulo, G., Citterio, E. and Serresi, M.
Molecular & Cellular Oncology 3
(3): e1152345.
May 2016
NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation.
Gargiulo, G., Levy, S., Bucci, G., Romanenghi, M., Fornasari, L., Beeson, K.Y., Goldberg, S.M., Cesaroni, M., Ballarini, M., Santoro, F., Bezman, N., Frige, G., Gregory, P.D., Holmes, M.C., Strausberg, R.L., Pelicci, P.G., Urnov, F.D. and Minucci, S.
Developmental Cell 16
(3): 466-481.
17 March 2009
In vivo shRNA screens in solid tumors.
Gargiulo, G., Serresi, M., Cesaroni, M., Hulsman, D. and van Lohuizen, M.
Nature Protocols 9
(12): 2880-2902.
December 2014
Cell states in cancer: drivers, passengers, and trailers.
Gargiulo, G., Serresi, M. and Marine, J.C.
Cancer Discovery 14
(4): 610-614.
4 April 2024
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.
Garipler, G., Lu, C., Morrissey, Al., Lopez-Zepeda, L.S., Pei, Y., Vidal, S.E., Zen Petisco Fiore, A.P., Aydin, B., Stadtfeld, M., Ohler, U., Mahony, S., Sanjana, N.E. and Mazzoni, E.O.
Cell Reports 38
(11): 110524.
15 March 2022
Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and expansion of cTfh1 cells and impaired B memory cell formation.
Garner-Spitzer, E., Wagner, A., Gudipati, V., Schoetta, A.M., Orola-Taus, M., Kundi, M., Kunert, R., Mayrhofer, P., Huppa, J.B., Stockinger, H., Carsetti, R., Gattinger, P., Valenta, R., Kratzer, B., Sehgal, A.N.A., Pickl, W.F., Reinisch, W., Novacek, G. and Wiedermann, U.
EBioMedicine 96
: 104788.
October 2023
SARS-CoV-2-specific antibody (Ab) levels and the kinetic of ab decline determine Ab persistence over 1 year.
Garner-Spitzer, E., Wagner, A., Kundi, M., Stockinger, H., Ohradanova-Repic, A., Gebetsberger, L., Schoetta, A.M., Gudipati, V., Huppa, J.B., Kunert, R., Mayrhofer, P., Kreil, T.R., Farcet, M.R., Hoeltl, E. and Wiedermann, U.
Frontiers in Medicine 9
: 822316.
15 February 2022
IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis.
Garnier, L., Pick, R., Montorfani, J., Sun, M., Brighouse, D., Liaudet, N., Kammertoens, T., Blankenstein, T., Page, N., Bernier-Latamani, J., Tran, N.L., Petrova, T.V., Merkler, D., Scheiermann, C. and Hugues, S.
Science Advances 8
(23): eabl5162.
8 June 2022
Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors.
Garrett, L., Zhang, J., Zimprich, A., Niedermeier, K.M., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Vogt Weisenhorn, D., Wurst, W. and Hoelter, S.M.
Frontiers in Behavioral Neuroscience 9
: 302.
12 November 2015
Luminal particles within cellular microtubules.
Garvalov, B.K., Zuber, B., Bouchet-Marquis, C., Kudryashev, M., Gruska, M., Beck, M., Leis, A., Frischknecht, F., Bradke, F., Baumeister, W., Dubochet, J. and Cyrklaff, M.
Journal of Cell Biology 174
(6): 759-765.
11 September 2006
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions.
Garvanska, D.H., Alvarado, R.E., Mundt, F.O., Lindqvist, R., Duel, J.K., Coscia, F., Nilsson, E., Lokugamage, K., Johnson, B.A., Plante, J.A., Morris, D.R., Vu, M.N., Estes, L.K., McLeland, A.M., Walker, J., Crocquet-Valdes, P.A., Mendez, B.L., Plante, K.S., Walker, D.H., Weisser, M.B., Överby, A.K., Mann, M., Menachery, V.D. and Nilsson, J.
EMBO Reports 25
(2): 902-926.
13 February 2024
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Gassen, N.C., Papies, J., Bajaj, T., Emanuel, J., Dethloff, F., Chua, R.L., Trimpert, J., Heinemann, N., Niemeyer, C., Weege, F., Hönzke, K., Aschman, T., Heinz, D.E., Weckmann, K., Ebert, T., Zellner, A., Lennarz, M., Wyler, E., Schroeder, S., Richter, A., Niemeyer, D., Hoffmann, K., Meyer, T.F., Heppner, F.L., Corman, V.M., Landthaler, M., Hocke, A.C., Morkel, M., Osterrieder, N., Conrad, C., Eils, R., Radbruch, H., Giavalisco, P., Drosten, C. and Müller, M.A.
Nature Communications 12
(1): 3818.
21 June 2021
A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
Gauss, R., Jarosch, E., Sommer, T. and Hirsch, C.
Nature Cell Biology 8
(8): 849-854.
August 2006
The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment.
Gauss, R., Sommer, T. and Jarosch, E.
EMBO Journal 25
(9): 1827-1835.
3 May 2006
New modules for the repeated internal and N-terminal epitope tagging of genes in Saccharomyces cerevisiae.
Gauss, R., Trautwein, M., Sommer, T. and Spang, A.
Yeast 22
(1): 1-12.
1 January 2005
A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells.
Gavvovidis, I., Rost, I., Trimborn, M., Kaiser, F.J., Purps, J., Wiek, C., Hanenberg, H., Neitzel, H. and Schindler, D.
PLoS ONE 7
(8): e40387.
30 August 2012
Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.
Gavvovidis, I., Leisegang, M., Willimsky, G., Miller, N.J., Nghiem, P. and Blankenstein, T.
Clinical Cancer Research 24
(15): 3644-3655.
August 2018
Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia.
Gazda, H.T., Grabowska, A., Merida-Long, L.B., Latawiec, E., Schneider, H.E., Lipton, J.M., Vlachos, A., Atsidaftos, E., Ball, S.E., Orfali, K.A., Niewiadomska, E., Da Costa, L., Tchernia, G., Niemeyer, C., Meerpohl, J.J., Stahl, J., Schratt, G., Glader, B., Backer, K., Wong, C., Nathan, D.G., Beggs, A.H. and Sieff, C.A.
American Journal of Human Genetics 79
(6): 1110-1118.
December 2006
Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.
Gazumyan, A., Timachova, K., Yuen, G., Siden, E., Di Virgilio, M., Woo, E.M., Chait, B.T., Reina San-Martin, B., Nussenzweig, M.C. and McBride, K.M.
Molecular and Cellular Biology 31
(3): 442-429.
February 2011
Magnetic resonance-guided biopsy of suspicious breast lesions with a handheld vacuum biopsy device.
Gebauer, B., Bostanjoglo, M., Moesta, K.T., Schneider, W., Schlag, P.M. and Felix, R.
Acta Radiologica 47
(9): 907-913.
November 2006
mBISON: Finding miRNA target over-representation in gene lists from ChIP-sequencing data.
Gebhardt, M.L., Mer, A.S. and Andrade-Navarro, M.A.
BMC Research Notes 8
(1): 157.
16 April 2015
Similarity in targets with REST points to neural and glioblastoma related miRNAs.
Gebhardt, M.L., Reuter, S., Mrowka, R. and Andrade-Navarro, M.A.
Nucleic Acids Research 42
(9): 5436-5446.
14 May 2014
New role for the (pro)renin receptor in T cell development.
Geisberger, S., Maschke, U., Gebhardt, M., Kleinewietfeld, M., Manzel, A., Linker, R.A., Chidgey, A., Dechend, R., Nguyen, G., Daumke, O., Muller, D.N., Wright, M.D. and Binger, K.J.
Blood 126
(4): 504-507.
23 July 2015
BTK inhibition limits microglia‑perpetuated CNS inflammation and promotes myelin repair.
Geladaris, A., Torke, S., Saberi, D., Alankus, Y.B., Streit, F., Zechel, S., Stadelmann-Nessler, C., Fischer, A., Boschert, U., Häusler, D. and Weber, M.S.
Acta Neuropathologica 147
(1): 75.
24 April 2024
Bruton's tyrosine kinase inhibitors in multiple sclerosis: pioneering the path towards treatment of progression?
Geladaris, A., Torke, S. and Weber, M.S.
CNS drugs 36
(10): 1019-1030.
October 2022
First genome-wide CNV mapping in FELIS CATUS using next generation sequencing data.
Genova, F., Longeri, M., Lyons, L.A., Bagnato, A. and Strillacci, M.G.
BMC Genomics 19
(1): 895.
10 December 2018
Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg, P., Astaburuaga-García, R., Bonaguro, L., Brumhard, S., Michalick, L., Lippert, L.J., Kostevc, T., Gäbel, C., Schneider, M., Streitz, M., Demichev, V., Gemünd, I., Barone, M., Tober-Lau, P., Helbig, E.T., Hillus, D., Petrov, L., Stein, J., Dey, H.P., Paclik, D., Iwert, C., Mülleder, M., Aulakh, S.K., Djudjaj, S., Bülow, R.D., Mei, H.E., Schulz, A.R., Thiel, A., Hippenstiel, S., Saliba, A.E., Eils, R., Lehmann, I., Mall, M.A., Stricker, S., Röhmel, J., Corman, V.M., Beule, D., Wyler, E., Landthaler, M., Obermayer, B., von Stillfried, S., Boor, P., Demir, M., Wesselmann, H., Suttorp, N., Uhrig, A., Müller-Redetzky, H., Nattermann, J., Kuebler, W.M., Meisel, C., Ralser, M., Schultze, J.L., Aschenbrenner, A.C., Thibeault, C., Kurth, F., Sander, L.E., Blüthgen, N. and Sawitzki, B.
Cell 185
(3): 493-512.
3 February 2022
Evidence-ranked motif identification.
Georgiev, S., Boyle, A.P., Jayasurya, K., Ding, X., Mukherjee, S. and Ohler, U.
Genome Biology 11
(2): R19.
15 February 2010
Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.
Gerbitz, A., Sukumar, M., Helm, F., Wilke, A., Friese, C., Fahrenwaldt, C., Lehmann, F.M., Loddenkemper, C., Kammertoens, T., Mautner, J., Schmitt, C.A., Blankenstein, T. and Bornkamm, G.W.
PLoS ONE 7
(3): e34552.
30 March 2012
Interwoven four-compartment capillary membrane technology for three-dimensional perfusion with decentralized mass exchange to scale up embryonic stem cell culture.
Gerlach, J., Luebberstedt, M., Edsbagge, J., Ring, A., Hout, M., Baun, M., Rossberg, I., Knoespel, F., Peters, G., Eckert, K., Wulf-Goldenberg, A., Bjoerquist, P., Stachelscheid, H., Urbaniak, T., Schatten, G., Miki, T., Schmelzer, E. and Zeilinger, K.
Cells Tissues Organs 192
(1): 39-49.
June 2010
pH-dependent protonation of surface carboxylate groups in PsbO enables local buffering and triggers structural changes.
Gerland, L. M., Friedrich, D., Hopf, L., Donovan, E., Wallmann, A., Erdmann, N., Diehl, A., Bommer, M., Buzar, K., Ibrahim, M., Schmieder, P., Dobbek, H., Zouni, A., Bondar, A.-N., Dau, H. and Oschkinat, H.
ChemBioChem 21
(11): 1597-1604.
2 June 2020
Precision oncology for acute myeloid leukemia using a knowledge bank approach.
Gerstung, M., Papaemmanuil, E., Martincorena, I., Bullinger, L., Gaidzik, V.I., Paschka, P., Heuser, M., Thol, F., Bolli, N., Ganly, P., Ganser, A., McDermott, U., Döhner, K., Schlenk, R.F., Döhner, H. and Campbell, P.J.
Nature Genetics 49
(3): 332-340.
March 2017
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B., Heuser, A., Wichter, T., Paul, M., Basson, C.T., McDermott, D.A., Lerman, B.B., Markowitz, S.M., Ellinor, P.T., MacRae, C.A., Peters, S., Grossmann, K.S., Drenckhahn, J., Michely, B., Sasse-Klaassen, S., Birchmeier, W., Dietz, R., Breithardt, G., Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36
(11): 1162-1164.
November 2004
Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: Implications for cell adhesion and signaling.
Ghadimi, B.M., Behrens, J., Hoffmann, I., Haensch, W., Birchmeier, W. and Schlag, P.M.
European Journal of Cancer 35
(1): 60-65.
January 1999
Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer.
Ghadjar, P., Coupland, S.E., Na, I.K., Noutsias, M., Letsch, A., Stroux, A., Bauer, S., Buhr, H.J., Thiel, E., Scheibenbogen, C. and Keilholz, U.
Journal of Clinical Oncology 24
(12): 1910-1916.
20 April 2006
Deep neural networks for interpreting RNA-binding protein target preferences.
Ghanbari, M. and Ohler, U.
Genome Research 30
(2): 214-226.
February 2020
Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S., Riemke, P., Schoenheit, J., Lenze, D., Stumm, J., Hoogenkamp, M., Lagendijk, A., Heinz, S., Bonifer, C., Bakkers, J., Abdelilah-Seyfried, S., Hummel, M. and Rosenbauer, F.
Blood 118
(8): 2275-2284.
25 August 2011
Strand-seq enables reliable separation of long reads by chromosome via expectation maximization.
Ghareghani, M., Porubskỳ, D., Sanders, A.D., Meiers, S., Eichler, E.E., Korbel, J.O. and Marschall, T.
Bioinformatics 34
(13): i115-i123.
1 July 2018
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Ghorashian, S., Veliça, P., Chua, I., McNicol, A., Carpenter, B., Holler, A., Nicholson, E., Ahmadi, M., Zech, M., Xue, S., Uckert, W., Morris, E., Chakraverty, R. and Stauss, H.J.
Journal of Immunology 194
(3): 1080-1089.
1 February 2015
PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating graft-versus-host-disease.
Ghosh, A., Holland, A.M., Dogan, Y., Yim, N., Rao, U.K., Young, L.F., West, M.L., Singer, N.V., Lee, H., Na, I.K., Tsai, J.J., Jenq, R., Penack, O., Hanash, A.M., Lezcano, C., Murphy, G.F., Liu, C., Sadelain, M., Sauer, M.G., Sant'Angelo, D. and van den Brink, M.R.M.
Cancer Research 73
(15): 4687-4696.
1 August 2013
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.
Giacopelli, B., Wang, M., Cleary, A., Wu, Y.Z., Schultz, A.R., Schmutz, M., Blachly, J.S., Eisfeld, A.K., Mundy-Bosse, B., Vosberg, S., Greif, P.A., Claus, R., Bullinger, L., Garzon, R., Coombes, K.R., Bloomfield, C.D., Druker, B.J., Tyner, J.W., Byrd, J.C. and Oakes, C.C.
Genome Research 31
(5): 747-761.
May 2021
Targeted application of human genetic variation can improve red blood cell production from stem cells.
Giani, F.C., Fiorini, C., Wakabayashi, A., Ludwig, L.S., Salem, R.M., Jobaliya, C.D., Regan, S.N., Ulirsch, J.C., Liang, G., Steinberg-Shemer, O., Guo, M.H., Esko, T., Tong, W., Brugnara, C., Hirschhorn, J.N., Weiss, M.J., Zon, L.I., Chou, S.T., French, D.L., Musunuru, K. and Sankaran, V.G.
Cell Stem Cell 18
(1): 73-78.
7 January 2016
TERT core promotor mutations in early-onset bladder cancer.
Giedl, J., Rogler, A., Wild, A., Riener, M.O., Filbeck, T., Burger, M., Ruemmele, P., Hurst, C., Knowles, M., Hartmann, A., Zinnall, U. and Stoehr, R.
Journal of Cancer 7
(8): 915-920.
7 May 2016
Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex.
Giehler, F., Ostertag, M.S., Sommermann, T., Weidl, D., Sterz, K.R., Kutz, H., Moosmann, A., Feller, S.M., Geerlof, A., Biesinger, B., Popowicz, G.M., Kirchmair, J. and Kieser, A.
Nature Communications 15
(1): 414.
10 January 2024
Alkemio: association of chemicals with biomedical topics by text and data mining.
Gijon-Correas, J.A., Andrade-Navarro, M.A. and Fontaine, J.F.
Nucleic Acids Research 42
(W1): W422-W429.
1 July 2014
Cxcl10(+) monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation.
Giladi, A., Wagner, L.K., Li, H., Dörr, D., Medaglia, C., Paul, F., Shemer, A., Jung, S., Yona, S., Mack, M., Leutz, A., Amit, I. and Mildner, A.
Nature Immunology 21
(5): 525-534.
May 2020
Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
Gillissen, B., Essmann, F., Graupner, V., Staerck, L., Radetzki, S., Doerken, B., Schulze-Osthoff, K. and Daniel, P.T.
EMBO Journal 22
(14): 3580-3590.
15 July 2003
Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
Gillissen, B., Essmann, F., Hemmati, P.G., Richter, A., Richter, A., Oztop, I., Chinnadurai, G., Doerken, B. and Daniel, P.T.
Journal of Cell Biology 179
(4): 701-715.
19 November 2007
Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode.
Gillissen, B., Richter, A., Richter, A., Overkamp, T., Essmann, F., Hemmati, P.G., Preissner, R., Belka, C. and Daniel, P.T.
Cell Death & Disease 4
: e643.
23 May 2013
Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin.
Gillissen, B., Richter, A., Essmann, F. and Kemmner, W.
BMC Cancer 21
(1): 971.
30 August 2021
Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B., Richter, A., Richter, A., Preissner, R., Schulze-Osthoff, K., Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292
(16): 6478-6492.
21 April 2017
Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.
Gillissen, B., Wendt, J., Richter, A., Richter, A., Mueer, A., Overkamp, T., Gebhardt, N., Preissner, R., Belka, C., Doerken, B. and Daniel, P.T.
Journal of Cell Biology 188
(6): 851-862.
22 March 2010
GPSeq reveals the radial organization of chromatin in the cell nucleus.
Girelli, G., Custodio, J., Kallas, T., Agostini, F., Wernersson, E., Spanjaard, B., Mota, A., Kolbeinsdottir, S., Gelali, E., Crosetto, N. and Bienko, M.
Nature Biotechnology 38
(10): 1184-1193.
October 2020
Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data using Decoil.
Giurgiu, M., Wittstruck, N., Rodriguez-Fos, E., Chamorro González, R., Brückner, L., Krienelke-Szymansky, A., Helmsauer, K., Hartebrodt, A., Euskirchen, P., Koche, R.P., Haase, K., Reinert, K. and Henssen, A.G.
Genome Research 34
(9): 1355-1364.
September 2024
Decoil: reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data.
Giurgiu, M., Wittstruck, N., Rodriguez-Fos, E., Chamorro González, R., Brückner, L., Krienelke-Szymansky, A., Helmsauer, K., Hartebrodt, A., Euskirchen, P., Koche, R.P., Haase, K., Reinert, K. and Henssen, A.G.
Lecture Notes in Computer Science 14758
: 406-411.
17 May 2024
Dual T cell receptor T cells with two defined specificities mediate tumor suppression via both receptors.
Gladow, M., Uckert, W. and Blankenstein, T.
European Journal of Immunology 34
(7): 1882-1891.
1 July 2004
NKp46 receptor-mediated interferon-γ production by natural killer cells increases fibronectin 1 to alter tumor architecture and control metastasis.
Glasner, A., Levi, A., Enk, J., Isaacson, B., Viukov, S., Orlanski, S., Scope, A., Neuman, T., Enk, C.D., Hanna, J.H., Sexl, V., Jonjic, S., Seliger, B., Zitvogel, L. and Mandelboim, O.
Immunity 48
(1): 107-119.
16 January 2018
A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use.
Gleicher, N., Metzger, J., Croft, G., Kushnir, V.A., Albertini, D.F. and Barad, D.H.
Reproductive Biology and Endocrinology 15
(1): 33.
27 April 2017
Characterization of the recombinant adenovirus vector AdYB-1: implications for oncolytic vector development.
Glockzin, G., Mantwill, K., Juerchott, K., Bernshausen, A., Ladhoff, A., Royer, H.D., Gansbacher, B. and Holm, P.S.
Journal of Virology 80
: 3904-3911.
15 April 2006
Lymphoma angiogenesis is orchestrated by noncanonical signaling pathways.
Gloger, M., Menzel, L., Grau, M., Vion, A.C., Anagnostopoulos, I., Zapukhlyak, M., Gerlach, K., Kammertöns, T., Hehlgans, T., Zschummel, M., Lenz, G., Gerhardt, H., Höpken, U.E. and Rehm, A.
Cancer Research 80
(6): 1316-1329.
March 2020
An unusual aspartic acid cluster in the reovirus attachment fiber s1 mediates stability at low pH and preserves trimeric organization.
Glorani, G., Ruwolt, M., Holton, N., Loll, B. and Neu, U.
Journal of Virology 96
(8): e0033122.
April 2022
Recombinant human erythropoietin, epoetin beta, in patients with relapsed lymphoma treated with aggressive sequential salvage chemotherapy - results of a randomized trial.
Glossmann, J.P., Engert, A., Wassmer, G., Flechtner, H., Ko, Y., Rudolph, C., Metzner, B., Doerken, B., Wiedenmann, S., Diehl, V. and Josting, A.
Annals of Hematology 82
(8): 469-475.
1 August 2003
The severe combined immunodeficient-human peripheral blood stem cell (SCID-huPBSC) mouse: a xenotransplant model for huPBSC-initiated hematopoiesis.
Goan, S.R., Fichtner, I., Just, U., Karawajew, L., Schultze, W., Krause, K.P., von Harsdorf, S., von Schilling, C. and Herrmann, F.
Blood 86
(1): 89-100.
1 July 1995
Lymphomas are sensitive to perforin-dependent cytotoxic pathways despite expression of PI-9 and overexpression of bcl-2.
Godal, R., Keilholz, U., Uharek, L., Letsch, A., Asemissen, A.M., Busse, A., Na, I.K., Thiel, E. and Scheibenbogen, C.
Blood 107
(8): 3205-3211.
15 April 2006
Axon guidance factor Slit2 inhibits neural invasion and metastasis in pancreatic cancer.
Goehrig, A., Detjen, K.M., Hilfenhaus, G., Koerner, J., Welzel, M., Arsenic, R., Schmuck, R., Bahra, M., Wu, J.Y., Wiedenmann, B. and Fischer, C.
Cancer Research 74
(5): 1529-1540.
1 March 2014
Importin provides a link between nuclear protein import and U snRNA export.
Goerlich, D., Kraft, R., Kostka, S., Vogel, F., Hartmann, E., Laskey, R.A., Mattaj, I.W. and Izaurralde, E.
Cell 87
(1): 21-32.
4 October 1996
The impact of short-term psycho-oncological interventions on the psychological outcome of cancer patients of a surgical-oncology department - A randomised controlled study.
Goerling, U., Foerg, A., Sander, S., Schramm, N. and Schlag, P.M.
European Journal of Cancer 47
(13): 2009-2014.
September 2011
Psychosozialer Betreuungsbedarf bei stationaeren Tumorpatienten. Untersuchungen an einer chirurgisch-onkologischen Schwerpunktklinik [Need for psychosocial care in in-patients with tumour disease. Investigations conducted in a clinic specializing in tumour surgery.].
Goerling, U., Odebrecht, S., Schiller, G. and Schlag, P.M.
Chirurg 77
: 41-46.
January 2006
Die Szenario-Methode als Verfahren zur Buergerbeteiligung? Staerken, Schwaechen, Moeglichkeiten und Problemquellen aus der Sicht von Teilnehmern des Workshops "Die Grenzen von Genen, Geld und Gelehrten".
Goersdorf, A. and Tannert, C.
Zeitschrift fuer Biopolitik 3
(1): 49-59.
1 January 2004
Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells.
Gogol-Döring, A., Ammar, I., Gupta, S., Bunse, M., Miskey, C., Chen, W., Uckert, W., Schulz, T.F., Izsvák, Z. and Ivics, Z.
Molecular Therapy 24
(3): 592-606.
March 2016
CancerResource - updated database of cancer-relevant proteins, mutations and interacting drugs.
Gohlke, B.O., Nickel, J., Otto, R., Dunkel, M. and Preissner, R.
Nucleic Acids Research 44
(D1): D932-D937.
4 January 2016
2D and 3D similarity landscape analysis identifies PARP as a novel off-target for the drug Vatalanib.
Gohlke, B.O., Overkamp, T., Richter, A., Richter, A., Daniel, P.T., Gillissen, B. and Preissner, R.
BMC Bioinformatics 16
(1): 308.
24 September 2015
Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O., Zincke, F., Eckert, A., Kobelt, D., Preissner, S., Liebeskind, J.M., Gunkel, N., Putzker, K., Lewis, J., Preissner, S., Kortüm, B., Walther, W., Mura, K., Bourne, P.E., Stein, U. and Preissner, R.
Clinical and Translational Medicine 12
(2): e726.
20 February 2022
Recent progress in structure and dynamics of dual-membrane-spanning bacterial nanomachines.
Gold, V. and Kudryashev, M.
Current Opinion in Structural Biology 39
: 1-7.
August 2016
Tissue factor expression pattern in human non-small cell lung cancer tissues indicate increased blood thrombogenicity and tumor metastasis.
Goldin-Lang, P., Tran, Q.V., Fichtner, I., Eisenreich, A., Antoniak, S., Schulze, K., Coupland, S.E., Poller, W., Schultheiss, H.P. and Rauch, U.
Oncology Reports 20
(1): 123-128.
July 2008
Thomsen-Friedenreich antigen: the "hidden" tumor antigen.
Goletz, S., Cao, Y., Danielczyk, A., Ravn, P., Schoeber, U. and Karsten, U.
Advances in Experimental Medicine and Biology 535
: 147-162.
1 January 2003
Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4.
Golfier, S., Kondo, S., Schulze, T., Takeuchi, T., Vassileva, G., Achtman, A.H., Graeler, M.H., Abbondanzo, S.J., Wiekowski, M., Kremmer, E., Endo, Y., Lira, S.A., Bacon, K.B. and Lipp, M.
FASEB Journal 24
(12): 4701-4710.
December 2010
Manufacture of gene modified human T cells with a memory stem/ central memory phenotype.
Gomez-Eerland, R., Nuijen, B., Heemskerk, B., van Rooij, N., van den Berg, J.H., Beijnen, J.H., Uckert, W., Kvistborg, P., Schumacher, T., Haanen, J.B.A.G. and Jorritsma, A.
Human Gene Therapy Methods 25
(5): 277-287.
October 2014
HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M., Yu, Y., Liang, L., Vuralli, D., Froehler, S., Kuehnen, P., Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J., Jia, S., Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7
(5): e602.
May 2019
The zinc finger antiviral protein ZAP restricts human cytomegalovirus and selectively binds and destabilizes viral UL4/UL5 transcripts.
Gonzalez-Perez, A.C., Stempel, M., Wyler, E., Urban, C., Piras, A., Hennig, T., Ganskih, S., Wei, Y., Heim, A., Landthaler, M., Pichlmair, A., Dölken, L., Munschauer, M., Erhard, F. and Brinkmann, M.M.
mBio 12
(3): e02683-20.
4 May 2021
Modulation of RNA polymerase assembly dynamics in transcriptional regulation.
Gorski, S.A., Snyder, S.K., John, S., Grummt, I. and Misteli, T.
Molecular Cell 30
(4): 486-497.
23 May 2008
Portable biomedical devices: a critical issue during telecare services design.
Gortzis, L.G., Bakettas, I., Makropoulos, C., Graschew, G. and Nikiforidis, G.
Informatics for Health and Social Care 33
(2): 91-98.
June 2008
Collaborative work during interventional radiological procedures based on a multicast satellite-terrestrial network.
Gortzis, L.G., Papadopoulos, H., Roelofs, T.A., Rakowsky, S., Karnabatidis, D., Siablis, D., Makropoulos, C., Nikiforidis, G. and Graschew, G.
IEEE Transactions on Information Technology in Biomedicine 11
(5): 597-599.
September 2007
Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells.
Gossen, M. and Bujard, H.
Nucleic Acids Research 21
(18): 4411-4412.
11 September 1993
RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.
Gottlieb, A., Althoff, K., Grunewald, L., Thor, T., Odersky, A., Schulte, M., Deubzer, H.E., Heukamp, L., Eggert, A., Schramm, A., Schulte, J.H. and Künkele, A.
Oncotarget 8
(17): 27882-27891.
25 April 2017
Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
Gottwein, E., Corcoran, D.L., Mukherjee, N., Skalsky, R.L., Hafner, M., Nusbaum, J.D., Shamulailatpam, P., Love, C.L., Dave, S.S., Tuschl, T., Ohler, U. and Cullen, B.R.
Cell Host & Microbe 10
(5): 515-526.
17 November 2011
A viral microRNA functions as an orthologue of cellular miR-155.
Gottwein, E., Mukherjee, N., Sachse, C., Frenzel, C., Majoros, W.H., Chi, J.T.A., Braich, R., Manoharan, M., Soutschek, J., Ohler, U. and Cullen, B.R.
Nature 450
(7172): 1096-1099.
13 December 2007
MLL1 is required for maintenance of intestinal stem cells.
Goveas, N., Waskow, C., Arndt, K., Heuberger, J., Zhang, Q., Alexopoulou, D., Dahl, A., Birchmeier, W., Anastassiadis, K., Stewart, A.F. and Kranz, A.
PLoS Genetics 17
(12): e1009250.
3 December 2021
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Gozdecka, M., Meduri, E., Mazan, M., Tzelepis, K., Dudek, M., Knights, A.J., Pardo, M., Yu, L., Choudhary, J.S., Metzakopian, E., Iyer, V., Yun, H., Park, N., Varela, I., Bautista, R., Collord, G., Dovey, O., Garyfallos, D.A., De Braekeleer, E., Kondo, S., Cooper, J., Göttgens, B., Bullinger, L., Northcott, P.A., Adams, D., Vassiliou, G.S. and Huntly, B.J.P.
Nature Genetics 50
(6): 883-894.
June 2018
Prognostic value of multimarker analysis in stage III colorectal cancer: one step forward towards an individualized therapy decision.
Grabowski, P., Maaser, K., Hanski, C., Stein, H., Sturm, I., Hopfenmueller, W., Doerken, B., Buhr, H.J., Zeitz, M. and Scheruebl, H.
Onkologie 28
(8-9): 399-403.
1 August 2005
Analysis of neuroendocrine differentiation and the p53/BAX pathway in UICC stage III colorectal carcinoma identifies patients with good prognosis.
Grabowski, P., Sturm, I., Schelwies, K., Maaser, K., Buhr, H.J., Doerken, B., Zeitz, M., Daniel, P.T. and Scheruebl, H.
International Journal of Colorectal Disease 21
: 221-230.
April 2006
Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells.
Grabundzija, I., Wang, J., Sebe, A., Erdei, Z., Kajdi, R., Devaraj, A., Steinemann, D., Szuhai, K., Stein, U., Cantz, T., Schambach, A., Baum, C., Izsvák, Z., Sarkadi, B. and Ivics, Z.
Nucleic Acids Research 41
(3): 1829-1847.
1 February 2013
EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue.
Graeler, M.H., Bernhardt, G. and Lipp, M.
Genomics 53
(2): 164-169.
15 October 1998
The sphingosine 1-phosphate receptor S1P4regulates cell shape and motility via coupling to Gi and G12/13.
Graeler, M.H., Grosse, R., Kusch, A., Kremmer, E., Gudermann, T. and Lipp, M.
Journal of Cellular Biochemistry 89
(3): 507-519.
1 June 2003
INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model.
Graeser, R., Esser, N., Unger, H., Fichtner, I., Zhu, A., Unger, C. and Kratz, F.
Investigational New Drugs 28
(1): 14-19.
February 2010
Expression and prognostic value of hemopoietic cytokine receptors in acute myeloid leukemia (AML): implications for future therapeutical strategies.
Graf, M., Hecht, K., Reif, S., Pelka-Fleischer, R., Pfister, K. and Schmetzer, H.
European Journal of Haematology 72
(2): 89-106.
February 2004
Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk.
Graf, M., Reif, S., Hecht, K., Pelka-Fleischer, R., Pfister, K., Nuessler, V. and Schmetzer, H.
European Journal of Haematology 71
(5): 366-376.
November 2003
Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.
Graf, R., Munschauer, M., Mastrobuoni, G., Mayr, F., Heinemann, U., Kempa, S., Rajewsky, N. and Landthaler, M.
RNA Biology 10
(7): 1146-1159.
1 July 2013
Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.
Graf, L., Dick, A., Sendker, F., Barth, E., Marz, M., Daumke, O. and Kochs, G.
Journal of Biological Chemistry 293
(9): 3056-3072.
2 March 2018
sgRNA sequence motifs blocking efficient CRISPR/Cas9-mediated gene editing.
Graf, R., Li, X., Chu, V.T. and Rajewsky, K.
Cell Reports 26
(5): 1098-1103.
29 January 2019
BCR-dependent lineage plasticity in mature B cells.
Graf, R., Seagal, J., Otipoby, K.L., Lam, K.P., Ayoub, S., Zhang, B., Sander, S., Chu, V.T. and Rajewsky, K.
Science 363
(6428): 748-753.
15 February 2019
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Grajales-Reyes, G.E., Iwata, A., Albring, J., Wu, X., Tussiwand, R., Kc, W., Kretzer, N.M., Briseno, C.G., Durai, V., Bagadia, P., Haldar, M., Schoenheit, J., Rosenbauer, F., Murphy, T.L. and Murphy, K.M.
Nature Immunology 16
(7): 708-717.
July 2015
Telemedicine in 20 years of CARS.
Graschew, G., Rakowsky, S., Roelofs, T.A. and Schlag, P.M.
International Congress Series 1281
: 175-179.
1 May 2005
Engineering for health in OP 2000.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
IFMBE Proceedings 22
: 871-874.
2008
Medical GRID and E-learning in the virtual hospital.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
IFMBE Proceedings 20
: 413-416.
2008
Network design for telemedicine - e-health using satellite technology.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
Studies in Health Technology and Informatics 131
: 67-82.
2008
Digital medicine in the virtual hospital of the future.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
International Journal of Computer Assisted Radiology and Surgery 1 (Suppl 7)
: 119-121.
June 2006
Interactive telemedical applications in OP 2000 via satellite.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
Biomedizinische Technik 47
(S1 Pt 1): 330-333.
2002
Telemedical applications and Grid technology.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Albayrak, S. and Kaiser, S.
1 January 2005
New trends in the virtualization of hospitals - tools for global e-Health.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Heinzlreiter, P., Kranzlmueller, D. and Volkert, J.
Studies in Health Technology and Informatics 121
: 168-175.
2006
Virtual hospital and digital medicine - Why is the GRID needed?
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Heinzlreiter, P., Kranzlmueller, D. and Volkert, J.
Studies in Health Technology and Informatics 120
: 295-304.
2006
VEMH - Virtual Euro-Mediterranean Hospital for global healthcare.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Kaiser, S. and Albayrak, S.
Studies in Health Technology and Informatics 114
: 39-45.
1 January 2005
DELTASS - Disaster emergency logistic telemedicine advanced satellites system: Telemedical services for disaster emergencies.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Lieber, A., Muller, U., Czymek, R. and Dusel, W.
International Journal of Risk Assessment and Management 9
(4): 351-366.
2008
Improved tumour response by laser light treatment.
Graschew, G., Smith, J., Rakowsky, S., Roelofs, T.A., Schlag, P.M. and Stein, U.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE 6991
: 69911A.
2 May 2008
The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S., Cabantog, A., MacPhee, L., Im, J., Ruess, C., Demir, B., Sperb, N., Rücker, F.G., Döhner, K., Herold, T., Pollack, J.R., Bullinger, L., Rouhi, A. and Kuchenbauer, F.
Haematologica 107
(8): 1758-1772.
August 2022
Personalizing precision medicine: Patients with AML perceptions about treatment decisions.
Grauman, A., Kontro, M., Haller, K., Nier, S., Aakko, S., Lang, K., Zingaretti, C., Meggiolaro, E., De Padova, S., Marconi, G., Martinelli, G., Heckman, C.A., Simonetti, G., Bullinger, L. and Kihlbom, U.
Patient Education and Counseling 115
: 107883.
5 July 2023
Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level.
Graupner, V., Alexander, E., Overkamp, T., Rothfuss, O., De Laurenzi, V., Gillissen, B.F., Daniel, P.T., Schulze-Osthoff, K. and Essmann, F.
Cell Death and Differentiation 18
(7): 1130-1139.
July 2011
Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP.
Gray, E.J., Petsalaki, E., James, D.A., Bagshaw, R.D., Stacey, M.M., Rocks, O., Gingras, A.C. and Pawson, T.
Journal of Biological Chemistry 289
(51): 35397-35408.
19 December 2014
CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.
Greensmith, R., Lape, I.T., Riella, C.V., Schubert, A.J., Metzger, J.J., Dighe, A.S., Tan, X., Hemmer, B., Rau, J., Wendlinger, S., Diederich, N., Schütz, A., Riella, L.V. and Kaminski, M.M.
EMBO Molecular Medicine 16
(10): 2619-2637.
14 October 2024
MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells.
Gregersen, L.H., Jacobsen, A., Frankel, L.B., Wen, J., Krogh, A. and Lund, A.H.
BMC Cancer 12
: 232.
12 June 2012
Survivin’ acute myeloid leukaemia - a personalised target for inv(16) patients.
Greiner, J., Brown, E., Bullinger, L., Hills, R.K., Morris, V., Döhner, H., Mills, K.I. and Guinn, B.A.
International Journal of Molecular Sciences 22
(19): 10482.
1 October 2021
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.
Greiner, J., Götz, M., Hofmann, S., Schrezenmeier, H., Wiesneth, M., Bullinger, L., Döhner, H. and Schneider, V.
Cancer Immunology Immunotherapy 69
(4): 629-640.
April 2020
Ensuring center quality, proper patient selection and fair access to chimeric antigen receptor T-cell therapy: position statement of the Austrian CAR-T Cell Network.
Greinix, H.T., Attarbaschi, A., Girschikofsky, M., Greil, R., Holter, W., Neumeister, P., Peters, C., Petzer, A., Rudzki, J., Schlenke, P., Schmitt, C.A., Schwinger, W., Wolf, D., Worel, N. and Jaeger, U.
memo: Magazine of European Medical Oncology 13
(1): 27-31.
March 2020
Markers of tumour angiogenesis and tumour cells in bone marrow in gastric cancer patients.
Gretschel, S., Astrosini, C.h., Vieth, M., Joens, T., Tomov, T., Hoecker, M., Schlag, P.M. and Kemmner, W.
European Journal of Surgical Oncology 34
(6): 642-647.
June 2008
Efficacy of Different Technical Procedures for Sentinel Lymph Node Biopsy in Gastric Cancer Staging.
Gretschel, S., Bembenek, A., Huenerbein, M., Dresel, S., Schneider, W. and Schlag, P.M.
Annals of Surgical Oncology 14
(7): 2028-2035.
July 2007
Prediction of gastric cancer lymph node status by sentinel lymph node biopsy and the Maruyama computer model.
Gretschel, S., Bembenek, A., Ulmer, C., Huenerbein, M., Markwardt, J., Schneider, U. and Schlag, P.M.
European Journal of Surgical Oncology 31
: 393-400.
1 January 2005
Lymphatic mapping und Sentinel-Lymphknotendiagnostik beim Magenkarzinom [Lymphatic mapping and sentinel lymph node biopsy in gastric cancer].
Gretschel, S., Bembenek, A., Ulmer, C., Huenerbein, M., Markwardt, J., Schneider, U. and Schlag, P.M.
Chirurg 74
(2): 132-138.
February 2003
Body mass index does not affect systematic D2 lymph node dissection and postoperative morbidity in gastric cancer patients.
Gretschel, S., Christoph, F., Bembenek, A., Estevez-Schwarz, L., Schneider, U. and Schlag, P.M.
Annals of Surgical Oncology 10
(4): 363-368.
May 2003
Gastric cancer surgery in elderly patients.
Gretschel, S., Estevez-Schwarz, L., Huenerbein, M., Schneider, U. and Schlag, P.M.
World Journal of Surgery 30
: 1468-1474.
August 2006
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Gretschel, S., Haensch, W., Schlag, P.M. and Kemmner, W.
Oncology 65
(2): 139-145.
2003
Prognostic value of cytokeratin-positive bone marrow cells of gastric cancer patients.
Gretschel, S., Schick, C., Schneider, U., Estevez-Schwarz, L., Bembenek, A. and Schlag, P.M.
Annals of Surgical Oncology 14
: 373-380.
February 2007
Current status of sentinel lymph node biopsy in adenocarcinoma of the distal esophagus, gastric cardia, and proximal stomach.
Gretschel, S. and Schlag, P.M.
Recent Results in Cancer Research 182
: 107-114.
2010
Multiviszerale Resektion als Baustein eines multimodalen Behandlungskonzepts beim lokal fortgeschrittenen oder peritoneal metastasierten Magenkarzinom
[Multivisceral resection as part of a multimodal treatment concept in locally progressed or peritoneally metastasized gastric cancer].
Gretschel, S. and Schlag, P.M.
Chirurgische Gastroenterologie 23
(4): 353-359.
December 2007
Surgical strategies for gastric cancer with synchronous peritoneal carcinomatosis.
Gretschel, S., Siegel, R., Estevez-Schwarz, L., Huenerbein, M., Schneider, U. and Schlag, P.M.
British Journal of Surgery 93
(12): 1530-1535.
December 2006
Lymphatic mapping and sentinel lymph node biopsy in epidermoid carcinoma of the anal canal.
Gretschel, S., Warnick, P., Bembenek, A., Dresel, S., Koswig, S., String, A., Huenerbein, M. and Schlag, P.M.
European Journal of Surgical Oncology 34
(8): 890-894.
August 2008
Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology.
Gries, J., Schumacher, D., Arand, J., Lutsik, P., Markelova, M.R., Fichtner, I., Walter, J., Sers, C. and Tierling, S.
Epigenetics 8
(7): 765-771.
July 2013
Morphological analysis and differentiation of benign cystic neoplasms of the pancreas using computed tomography and magnetic resonance imaging.
Grieser, C., Heine, G., Stelter, L., Steffen, I.G., Rothe, J.H., Walter, T.C., Fischer, C., Bahra, M. and Denecke, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 185
(3): 219-227.
March 2013
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
Griger, J., Widholz, S.A., Jesinghaus, M., de Andrade Krätzig, N., Lange, S., Engleitner, T., Montero, J.J., Zhigalova, E., Öllinger, R., Suresh, V., Winkler, W., Lier, S., Baranov, O., Trozzo, R., Ben Khaled, N., Chakraborty, S., Yu, J., Konukiewitz, B., Steiger, K., Pfarr, N., Rajput, A., Sailer, D., Keller, G., Schirmacher, P., Röcken, C., Fagerstedt, K.W., Mayerle, J., Schmidt-Supprian, M., Schneider, G., Weichert, W., Calado, D.P., Sommermann, T., Klöppel, G., Rajewsky, K., Saur, D. and Rad, R.
Cancer Cell 41
(7): 1327-1344.e10.
10 July 2023
Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T., Stein, S., Qi, J., Wende, H., Garratt, A.N., Nave, K.A., Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110
(45): 18174-18179.
5 November 2013
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells.
Grimes, K., Jeong, H., Amoah, A., Xu, N., Niemann, J., Raeder, B., Hasenfeld, P., Stober, C., Rausch, T., Benito, E., Jann, J.C., Nowak, D., Emini, R., Hoenicka, M., Liebold, A., Ho, A., Shuai, S., Geiger, H., Sanders, A.D. and Korbel, J.O.
Nature Genetics 56
(6): 1134-1146.
June 2024
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
Grimm, J., Sachs, M., Britsch, S., Di Cesare, S., Schwarz-Romond, T. and Birchmeier, W.
Journal of Cell Biology 154
(2): 345-354.
23 July 2001
The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat, J., Heuberger, J., Vidal, R., Goveas, N., Kosel, F., Berenguer-Llergo, A., Kranz, A., Wulf-Goldenberg, A., Behrens, D., Melcher, B., Sauer, S., Vieth, M., Batlle, E., Stewart, A. and Birchmeier, W.
Nature Communications 11
(1): 6422.
21 December 2020
Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.
Grinat, J., Kosel, F., Goveas, N., Kranz, A., Alexopoulou, D., Rajewsky, K., Sigal, M., Stewart, A.F. and Heuberger, J.
Life Science Alliance 5
(4): e202101187.
April 2022
Cell cycle-controlled interaction of nucleolin with the retinoblastoma protein and cancerous cell transformation.
Grinstein, E., Shan, Y., Karawajew, L., Snijders, P.J., Meijer, C.J., Royer, H.D. and Wernet, P.
Journal of Biological Chemistry 281
(31): 22223-22235.
4 August 2006
Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancer.
Grinstein, E., Wernet, P., Snijders, P.J.F., Rosl, F., Weinert, I., Jia, W.T., Kraft, R., Schewe, C., Schwabe, M., Hauptmann, S., Dietel, M., Meijer, C.J.L.M. and Royer, H.D.
Journal of Experimental Medicine 196
(8): 1067-1078.
21 October 2002
Mechanism of virus attenuation by codon pair deoptimization.
Groenke, N., Trimpert, J., Merz, S., Conradie, A.M., Wyler, E., Zhang, H., Hazapis, O.G., Rausch, S., Landthaler, M., Osterrieder, N. and Kunec, D.
Cell Reports 31
(4): 107586.
28 April 2020
A multichannel time-domain scanning fluorescence mammograph: Performance assessment and first in vivo results.
Grosenick, D., Hagen, A., Steinkellner, O., Poellinger, A., Burock, S., Schlag, P.M., Rinneberg, H. and Macdonald, R.
Review of Scientific Instruments 82
(2): 1024302.
February 2011
Evaluation of higher-order time-domain perturbation theory of photon diffusion on breast-equivalent phantoms and optical mammograms.
Grosenick, D., Kummrow, A., Macdonald, R., Schlag, P.M. and Rinneberg, H.
Physical Review E 76
(6 Pt 1): 061908.
December 2007
Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients.
Grosenick, D., Moesta, K.T., Moeller, M., Mucke, J., Wabnitz, H., Gebauer, B., Stroszczynski, C., Wassermann, B., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 50
: 2429-2449.
1 January 2005
Time-domain optical mammography: initial clinical results on detection and characterization of breast tumors.
Grosenick, D., Moesta, K.T., Wabnitz, H., Mucke, J., Stroszczynski, C., Macdonald, R., Schlag, P.M. and Rinneberg, H.
Applied Optics 42
(16): 3170-3186.
1 June 2003
Concentration and oxygen saturation of haemoglobin of 50 breast tumours determined by time-domain optical mammography.
Grosenick, D., Wabnitz, H., Moesta, K.T., Mucke, J., Moeller, M., Stroszczynski, C., Stoessel, J., Wassermann, B., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 49
(7): 1165-1181.
18 March 2004
Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas.
Grosenick, D., Wabnitz, H., Moesta, K.T., Mucke, J., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 50
: 2451-2468.
1 January 2005
Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit.
Grosheva, A.S., Zharkov, D.O., Stahl, J., Gopanenko, Al.V., Tupikin, A.E., Kabilov, M.R., Graifer, D.M. and Karpova, G.G.
Nucleic Acids Research 45
(7): 3833-3843.
20 April 2017
Therapy-related AML: long-term outcome in a large cohort of AML-patients with intensive and non-intensive therapy.
Gross, S., Ihlow, J., Busack, L., Adamiak, K., Schrezenmeier, J., Jesse, J., Schwarz, M., Flörcken, A., Vuong, L.G., Rieger, K., Krönke, J., le Coutre, P., Boldt, V., von Brünneck, A.C., Horst, D., Burmeister, T., Blau, I.W., Keller, U., Bullinger, L. and Westermann, J.
Blood Cancer Journal 14
(1): 160.
16 September 2024
Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S., Eckert, C., Arkona, C., Radetzki, S., Böhm, K., Heinemann, U., Wolber, G., von Kries, J.P., Birchmeier, W. and Rademann, J.
ChemMedChem 10
(5): 815-826.
May 2015
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
Grossmann, K.S., Grund, C., Huelsken, J., Behrend, M., Erdmann, B., Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 167
(1): 149-160.
11 October 2004
The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H., Paul, F.E., Cheret, C., Garratt, A.N., Zurborg, S., Feinberg, K., Besser, D., Schulz, H., Peles, E., Selbach, M., Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106
(39): 16704-16709.
29 September 2009
Emotional voice processing: investigating the role of genetic variation in the serotonin transporter across development.
Grossmann, T., Vaish, A., Franz, J., Schroeder, R., Stoneking, M. and Friederici, A.D.
PLoS ONE 8
(7): e68377.
8 July 2013
Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.
Grosswendt, S., Filipchyk, A., Manzano, M., Klironomos, F., Schilling, M., Herzog, M., Gottwein, E. and Rajewsky, N.
Molecular Cell 54
(6): 1042-1054.
19 June 2014
Epigenetic regulator function through mouse gastrulation.
Grosswendt, S., Kretzmer, H., Smith, Z.D., Kumar, A.S., Hetzel, S., Wittler, L., Klages, S., Timmermann, B., Mukherji, S. and Meissner, A.
Nature 584
(7819): 102-108.
6 August 2020
Ectopic expression of E2F1 stimulates beta cell proliferation and function.
Grouwels, G., Cai, Y., Hoebeke, I., Leuckx, G., Heremans, Y., Ziebold, U., Stange, G., Chintinne, M., Ling, Z., Pipeleers, D., Heimberg, H. and Van de Casteele, M.
Diabetes 59
(6): 1435-1444.
June 2010
T-cell-mediated lysis of B cells induced by a CD19xCD3 bispecific single-chain antibody is perforin dependent and death receptor independent.
Gruen, M., Bommert, K. and Bargou, R.C.
Cancer Immunology Immunotherapy 53
(7): 625-632.
1 January 2004
Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay.
Gruetzmann, R., Molnar, B., Pilarsky, C., Habermann, J.K., Schlag, P.M., Saeger, H.D., Miehlke, S., Stolz, T., Model, F., Roblick, U.J., Bruch, H.P., Koch, R., Liebenberg, V., Devos, T., Song, X., Day, R.H., Sledziewski, A.Z. and Lofton-Day, C.
PLoS ONE 3
(11): e3759.
19 November 2008
A reproducible bioprinted 3D tumor model serves as a preselection tool for CAR T cell therapy optimization.
Grunewald, L., Lam, T., Andersch, L., Klaus, A., Schwiebert, S., Winkler, A., Gauert, A., Heeren-Hagemann, A.I., Astrahantseff, K., Klironomos, F., Thomas, A., Deubzer, H.E., Henssen, A.G., Eggert, A., Schulte, J.H., Anders, K., Kloke, L. and Künkele, A.
Frontiers in Immunology 12
: 689697.
29 June 2021
Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Grunwald, S., Hopf, L.V.M., Bock-Bierbaum, T., Lally, C.C.M., Spahn, C.M.T. and Daumke, O.
Nature Communications 11
(1): 5506.
2 November 2020
Recombination between heterologous human acrocentric chromosomes.
Guarracino, A., Buonaiuto, S., de Lima, L.G., Potapova, T., Rhie, A., Koren, S., Rubinstein, B., Fischer, C., Gerton, J.L., Phillippy, A.M., Colonna, V. and Garrison, E.
Nature 617
(7960): 335-343.
11 May 2023
Inefficient CAR-proximal signaling blunts antigen sensitivity.
Gudipati, V., Rydzek, J., Doel-Perez, I., Gonçalves, V.D.R., Scharf, L., Königsberger, S., Lobner, E., Kunert, R., Einsele, H., Stockinger, H., Hudecek, M. and Huppa, J.B.
Nature Immunology 21
(8): 848-856.
August 2020
Bio++: efficient extensible libraries and tools for computational molecular evolution.
Gueguen, L., Gaillard, S., Boussau, B., Gouy, M., Groussin, M., Rochette, N.C., Bigot, T., Fournier, D., Pouyet, F., Cahais, V., Bernard, A., Scornavacca, C., Nabholz, B., Haudry, A., Dachary, L., Galtier, N., Belkhir, K. and Dutheil, J.Y.
Molecular Biology and Evolution 30
(8): 1745-1750.
August 2013
Disruption of cell death signaling in cancer: impact on disease prognosis and response to therapy.
Guener, D., Belka, C. and Daniel, P.T.
Current Medicinal Chemistry Anti-Cancer Agents 3
(5): 319-326.
1 September 2003
Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.
Guener, D., Sturm, I., Hemmati, P., Hermann, S., Hauptmann, S., Wurm, R., Budach, V., Doerken, B., Lorenz, M. and Daniel, P.T.
International Journal of Cancer 103
(4): 445-454.
10 February 2003
Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Guenther, S., Schlundt, A., Sticht, J., Roske, Y., Heinemann, U., Wiesmueller, K.H., Jung, G., Falk, K., Roetzschke, O. and Freund, C.
Proceedings of the National Academy of Sciences of the United States of America 107
(51): 22219-22224.
21 December 2010
Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease.
Guenther, U.P., Handoko, L., Varon, R., Stephani, U., Tsao, C.Y., Mendell, J.R., Lützkendorf, S., Hübner, C., von Au, K., Jablonka, S., Dittmar, G., Heinemann, U., Schuetz, A. and Schuelke, M.
Journal of Molecular Medicine 87
(1): 31-41.
January 2009
Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis.
Guenthert, U., Schwaerzler, C., Wittig, B., Laman, J., Ruiz, P., Stauder, R., Bloem, A., Smadja-Joffe, F., Zoeller, M. and Rolink, A.
Advances in Experimental Medicine and Biology 451
: 43-49.
1998
Human peripheral blood and bone marrow Epstein-Barr virus-specific T-cell repertoire in latent infection reveals distinct memory T-cell subsets.
Guerreiro, M., Na, I.K., Letsch, A., Haase, D., Bauer, S., Meisel, C., Roemhild, A., Reinke, P., Volk, H.D. and Scheibenbogen, C.
European Journal of Immunology 40
(6): 1566-1576.
June 2010
Interdisziplinaere Tumorkonferenzen : regionale und ueberregionale telemedizinische und teleradiologische Anbindung von Tumorzentren [Interdisciplinary tumor boards : regional and supraregional telemedical and teleradiological links to tumor boards].
Guettler, F.V., Rakowsky, S., Nagel, S.N., Teichgraeber, U. and Schlag, P.M.
Onkologe 18
(5): 389-397.
May 2012
Technical considerations for the use of CRISPR/Cas9 in hematology research.
Gundry, M.C., Dever, D.P., Yudovich, D., Bauer, D.E., Haas, S., Wilkinson, A.C. and Singbrant, S.
Experimental Hematology 54
: 4-11.
October 2017
How to find genomic regions relevant for gene regulation.
Guo, X., Ohler, U. and Yildirim, F.
Medizinische Genetik 33
(2): 157-165.
14 August 2021
Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.
Gupta, S., Hoepner, S., Rupp, B., Guenther, S., Dickhaut, K., Agarwal, N., Cardoso, M.C., Kuehne, R., Wiesmueller, K.H., Jung, G., Falk, K. and Roetzschke, O.
PLoS ONE 3
(3): e1814.
19 March 2008
RNA-containing adenovirus/polyethylenimine transfer complexes effectively transduce dendritic cells and induce antigen-specific T cell responses.
Gust, T.C., Diebold, S.S., Cotten, M. and Zenke, M.
Journal of Gene Medicine 6
(4): 464-470.
1 April 2004
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.
Guy, C.S., Vignali, K.M., Temirov, J., Bettini, M.L., Overacre, A.E., Smeltzer, M., Zhang, H., Huppa, J.B., Tsai, Y.H., Lobry, C., Xie, J., Dempsey, P.J., Crawford, H.C., Aifantis, I., Davis, M.M. and Vignali, D.A.A.
Nature Immunology 14
(3): 262-70.
March 2013
Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.
Gyoerffy, B., Serra, V., Juerchott, K., Abdul-Ghani, R., Garber, M., Stein, U., Petersen, I., Lage, H., Dietel, M. and Schaefer, R.
Oncogene 24
(15): 7542-7551.
25 July 2005
Splenic marginal zone granulocytes acquire an accentuated neutrophil B cell-helper phenotype in chronic lymphocytic leukemia.
Gätjen, M., Brand, F., Grau, M., Gerlach, K., Kettritz, R., Westermann, J., Anagnostopoulos, I., Lenz, P., Lenz, G., Höpken, U.E. and Rehm, A.
Cancer Research 76
(18): 5253-5265.
15 September 2016
Placental growth factor promotes neural invasion and predicts disease prognosis in resectable pancreatic cancer.
Göhrig, A., Hilfenhaus, G., Rosseck, F., Welzel, M., Moser, B., Barbone, G., Kunze, C.A., Rein, J., Wilken, G., Böhmig, M., Malinka, T., Tacke, F., Bahra, M., Detjen, K.M. and Fischer, C.
Journal of Experimental & Clinical Cancer Research 43
(1): 153.
30 May 2024
Temporal analysis of T-cell receptor-imposed forces via quantitative single molecule FRET measurements.
Göhring, J., Kellner, F., Schrangl, L., Platzer, R., Klotzsch, E., Stockinger, H., Huppa, J.B. and Schütz, G.J.
Nature Communications 12
(1): 2502.
4 May 2021
AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Götz, F., Roske, Y., Schulz, M.S., Autenrieth, K., Bertinetti, D., Faelber, K., Zühlke, K., Kreuchwig, A., Kennedy, E., Krause, G., Daumke, O., Herberg, F.W., Heinemann, U. and Klussmann, E.
Biochemical Journal 473
(13): 1881-1894.
28 June 2016
Saffron crudes and compounds restrict MACC1-dependent cell proliferation and migration of colorectal cancer cells.
Güllü, N., Kobelt, D., Brim, H., Rahman, S., Timm, L., Smith, J., Soleimani, A., Di Marco, S., Bisti, S., Ashktorab, H. and Stein, U.
Cells 9
(8): 1829.
3 August 2020
MACC1-dependent antitumor effect of curcumin in colorectal cancer.
Güllü, N., Smith, J., Herrmann, P. and Stein, U.
Nutrients 14
(22): 4792.
12 November 2022
A molecularly characterized preclinical platform of subcutaneous renal cell carcinoma (RCC) patient-derived xenograft models to evaluate novel treatment strategies.
Gürgen, D., Becker, M., Dahlmann, M., Flechsig, S., Schaeffeler, E., Büttner, F.A., Schmees, C., Bohnert, R., Bedke, J., Schwab, M., Wendler, J.J., Schostak, M., Jandrig, B., Walther, W. and Hoffmann, J.
Frontiers in Oncology 12
: 889789.
21 June 2022
Constitutive monocyte-restricted activity of NF-M, a nuclear factor that binds to a C/EBP motif.
Haas, J.G., Stroebel, M., Leutz, A., Wendelgass, P., Mueller, C., Sterneck, E., Riethmueller, G. and Ziegler-Heitbrock, H.W.
Journal of Immunology 149
(1): 237-243.
1 July 1992
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors.
Haas, S., Hansson, J., Klimmeck, D., Loeffler, D., Velten, L., Uckelmann, H., Wurzer, S., Prendergast, Á.M., Schnell, A., Hexel, K., Santarella-Mellwig, R., Blaszkiewicz, S., Kuck, A., Geiger, H., Milsom, M.D., Steinmetz, L.M., Schroeder, T., Trumpp, A., Krijgsveld, J. and Essers, M.A.G.
Cell Stem Cell 17
(4): 422-34.
1 October 2015
Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway.
Habermehl, D., Kammerer, B., Handrick, R., Eldh, T., Gruber, C., Cordes, N., Daniel, P.T., Plasswilm, L., Bamberg, M., Belka, C. and Jendrossek, V.
BMC Cancer 6
: 14.
17 January 2006
A prospective observational study of real-world treatment and outcome in secondary CNS lymphoma.
Habringer, S., Demel, U.M., Fietz, A.K., Lammer, F., Schroers, R., Hofer, S., Bairey, O., Braess, J., Meier-Stiegen, A.S., Stuhlmann, R., Schmidt-Hieber, M., Hoffmann, J., Zinngrebe, B., Kaiser, U., Reimer, P., Möhle, R., Fix, P., Höffkes, H.G., Langenkamp, U., Büschenfelde, C.M.Z., Hopfer, O., Stoltefuß, A., La Rosée, P., Blasberg, H., Jordan, K., Kaun, S., Meurer, A., Unteroberdörster, M., von Brünneck, A.C., Capper, D., Heppner, F.L., Chapuy, B., Janz, M., Schwartz, S., Konietschke, F., Vajkoczy, P., Korfel, A. and Keller, U.
European Journal of Cancer 196
: 113436.
January 2024
A diagnostic challenge of KIT p.V559D and BRAF p.G469A mutations in a paragastric mass.
Habringer, S., Ihlow, J., Kleo, K., Klostermann, A., Schmidt, M., Chai, L., Knödler, M., Leyvraz, S., Sigler, C., Sinn, B., Maschmeyer, G., Jegodka, Y., Benary, M., Ott, C.E., Tinhofer, I., Schäfer, R., Möbs, M., Keller, U., Keilholz, U. and Rieke, D.T.
Oncologist 29
(10): 908-912.
October 2024
Regulated intramembrane proteolysis and degradation of murine epithelial cell adhesion molecule mEpCAM.
Hachmeister, M., Bobowski, K.D., Hogl, S., Dislich, B., Fukumori, A., Eggert, C., Mack, B., Kremling, H., Sarrach, S., Coscia, F., Zimmermann, W., Steiner, H., Lichtenthaler, S.F. and Gires, O.
PLoS ONE 8
(8): e71836.
29 August 2013
Transcriptional profiling identifies Id2 function in dendritic cell development.
Hacker, C., Kirsch, R.D., Ju, X.S., Hieronymus, T., Gust, T.C., Kuhl, C., Jorgas, T., Kurz, S.M., Rose-John, S., Yokota, Y. and Zenke, M.
Nature Immunology 4
(4): 380-386.
April 2003
Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Hadjihannas, M.V., Brueckner, M., Jerchow, B., Birchmeier, W., Dietmaier, W. and Behrens, J.
Proceedings of the National Academy of Sciences of the United States of America 103
(28): 10747-10752.
11 July 2006
Hand grip strength in patients with advanced cancer: a prospective study.
Hadzibegovic, S., Porthun, J., Lena, A., Weinlaänder, P., Lück, L.C., Potthoff, S.K., Rösnick, L., Fröhlich, A.K., Ramer, L.V., Sonntag, F., Wilkenshoff, U., Ahn, J., Keller, U., Bullinger, L., Mahabadi, A.A., Totzeck, M., Rassaf, T., von Haehling, S., Coats, A.J.S., Anker, S.D., Roeland, E.J., Landmesser, U. and Anker, M.S.
Journal of Cachexia Sarcopenia and Muscle 14
(4): 1682-1694.
August 2023
Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.
Haeaerae, O., Fujimori, S., Schmidt-Ullrich, R., Hartmann, C., Thesleff, I. and Mikkola, M.L.
Development 138
(13): 2681-2691.
July 2011
Alterations of pre-mRNA splicing in human inflammatory bowel disease.
Haesler, R., Kerick, M., Mah, N., Hultschig, C., Richter, G., Bretz, F., Sina, C., Lehrach, H., Nietfeld, W., Schreiber, S. and Rosenstiel, P.
European Journal of Cell Biology 90
(6-7): 603-611.
June 2011
Morphologic dysplasia in de novo acute myeloid leukemia (AML) is related to unfavorable cytogenetics but has no independent prognostic relevance under the conditions of intensive induction therapy: results of a multiparameter analysis from the German AML Cooperative Group studies.
Haferlach, T., Schoch, C., Loeffler, H., Gassmann, W., Kern, W., Schnittger, S., Fonatsch, C., Ludwig, W.D., Wuchter, C., Schlegelberger, B., Staib, P., Reichle, A., Kubica, U., Eimermacher, H., Balleisen, L., Grueneisen, A., Haase, D., Aul, C., Karow, J., Lengfelder, E., Woermann, B., Heinecke, A., Sauerland, M.C., Buechner, T. and Hiddemann, W.
Journal of Clinical Oncology 21
: 256-265.
15 January 2003
McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.
Hafez, D., Karabacak, A., Krueger, S., Hwang, Y.C., Wang, L.S., Zinzen, R.P. and Ohler, U.
Genome Biology 18
(1): 199.
26 October 2017
Transcription factor induction of vascular blood stem cell niches in vivo.
Hagedorn, E.J., Perlin, J.R., Freeman, R.J., Wattrus, S.J., Han, T., Mao, C., Kim, J.W., Fernández-Maestre, I., Daily, M.L., D'Amato, C., Fairchild, M.J., Riquelme, R., Li, B., Ragoonanan, D.A.V.E., Enkhbayar, K., Henault, E.L., Wang, H.G., Redfield, S.E., Collins, S.H., Lichtig, A., Yang, S., Zhou, Y., Kunar, B., Gomez-Salinero, J.M., Dinh, T.T., Pan, J., Holler, K., Feldman, H.A., Butcher, E.C., van Oudenaarden, A., Rafii, S., Junker, J.P. and Zon, L.I.
Developmental Cell 58
(12): 1037-1051.
19 June 2023
Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis.
Hagemann, C., Fuchs, S., Monoranu, C.M., Herrmann, P., Smith, J., Hohmann, T., Grabiec, U., Kessler, A.F., Dehghani, F., Loehr, M., Ernestus, R.I., Vince, G.H. and Stein, U.
Neuro-Oncology 15
(12): 1696-1709.
December 2013
Circulating MACC1 transcripts in glioblastoma patients predict prognosis and treatment response.
Hagemann, C., Neuhaus, N., Dahlmann, M., Kessler, A.F., Kobelt, D., Herrmann, P., Eyrich, M., Freitag, B., Linsenmann, T., Monoranu, C.M., Ernestus, R.I., Löhr, M. and Stein, U.
Cancers 11
(6): 825.
13 June 2019
Late-fluorescence mammography assesses tumor capillary permeability and differentiates malignant from benign lesions.
Hagen, A., Grosenick, D., Macdonald, R., Rinneberg, H., Burock, S., Warnick, P., Poellinger, A. and Schlag, P.M.
Optics Express 17
(19): 17016-17033.
14 September 2009
miR-142 favors naïve B cell residence in peripheral lymph nodes.
Hagen, M., Chakraborty, T., Olson, W.J., Heitz, M., Hermann-Kleiter, N., Kimpel, J., Jenewein, B., Pertoll, J., Labi, V., Rajewsky, K. and Derudder, E.
Frontiers in Immunology 13
: 847415.
10 November 2022
Diffusion maps for high-dimensional single-cell analysis of differentiation data.
Haghverdi, L., Buettner, F. and Theis, F.J.
Bioinformatics 31
(18): 2989-2998.
15 September 2015
Diffusion pseudotime robustly reconstructs lineage branching.
Haghverdi, L., Büttner, M., Wolf, F.A., Buettner, F. and Theis, F.J.
Nature Methods 13
(10): 845-848.
October 2016
Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors.
Haghverdi, L., Lun, A.T.L., Morgan, M.D. and Marioni, J.C.
Nature Biotechnology 36
(5): 421-427.
May 2018
Crystal structure and site-directed mutagenesis of Bacillus macerans endo-1,3-1,4-beta-glucanase.
Hahn, M., Olsen, O., Politz, O., Borriss, R. and Heinemann, U.
Journal of Biological Chemistry 270
(7): 3081-3088.
17 February 1995
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M., Pablo-Tortola, C., Todiras, M., Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M., Jarosch, E., Sommer, T., Bröker, B.M., Felix, S.B., Scheidereit, C., Weber-Carstens, S., Butter, C., Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 11
(1): 103-119.
February 2020
Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines.
Hailfinger, S., Nogai, H., Pelzer, C., Jaworski, M., Cabalzar, K., Charton, J.E., Guzzardi, M., Decaillet, C., Grau, M., Doerken, B., Lenz, P., Lenz, G. and Thome, M.
Proceedings of the National Academy of Sciences of the United States of America 108
(35): 14596-14601.
30 August 2011
A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3.
Halatsch, M.E., Kast, R.E., Karpel-Massler, G., Mayer, B., Zolk, O., Schmitz, B., Scheuerle, A., Maier, L., Bullinger, L., Mayer-Steinacker, R., Schmidt, C., Zeiler, K., Elshaer, Z., Panther, P., Schmelzle, B., Hallmen, A., Dwucet, A., Siegelin, M.D., Westhoff, M.A., Beckers, K., Bouche, G. and Heiland, T.
Neuro-Oncology Advances 3
(1): vdab075.
7 August 2021
Light-induced reduction of bovine adrenodoxin via the covalently bound ruthenium(II) bipyridyl complex: Intramolecular electron transfer and crystal structure.
Halavaty, A., Mueller, J.J., Contzen, J., Jung, C., Hannemann, F., Bernhardt, R., Galander, M., Lendzian, F. and Heinemann, U.
Biochemistry 45
(3): 709-718.
24 January 2006
Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.
Halik, A., Tilgner, M., Silva, P., Estrada, N., Altwasser, R., Jahn, E., Heuser, M., Hou, H.A., Pratcorona, M., Hills, R.K., Metzeler, K.H., Fenwarth, L., Dolnik, A., Terre, C., Kopp, K., Blau, O., Szyska, M., Christen, F., Krönke, J., Vasseur, L., Löwenberg, B., Esteve, J., Valk, P.J.M., Duchmann, M., Chou, W.C., Linch, D.C., Döhner, H., Gale, R.E., Döhner, K., Bullinger, L., Yoshida, K. and Damm, F.
Journal of Hematology & Oncology 17
(1): 70.
19 August 2024
Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells.
Halvorsen, B., Dahl, T.B., Smedbakken, L.M., Singh, A., Michelsen, A.E., Skjelland, M., Krohg-Sørensen, K., Russell, D., Höpken, U.E., Lipp, M., Damås, J.K., Holm, S., Yndestad, A., Biessen, E.A. and Aukrust, P.
Cardiovascular Research 102
(1): 148-156.
1 April 2014
A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signaling.
Hamann, L., Kumpf, O., Mueller, M., Visintin, A., Eckert, J., Schlag, P.M. and Schumann, R.R.
Genes and Immunity 5
(4): 283-288.
1 June 2004
Comparative profiling of the novel epothilone, sagopilone, in xenografts derived from primary non-small cell lung cancer.
Hammer, S., Sommer, A., Fichtner, I., Becker, M., Rolff, J., Merk, J., Klar, U. and Hoffmann, J.
Clinical Cancer Research 16
(5): 1452-1465.
1 March 2010
Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice.
Hammer, K.P., Mustroph, J., Stauber, T., Birchmeier, W., Wagner, S. and Maier, L.S.
PLoS ONE 16
(6): e0252649.
4 June 2021
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.
Hammer, Q., Rückert, T., Borst, E.M., Dunst, J., Haubner, A., Durek, P., Heinrich, F., Gasparoni, G., Babic, M., Tomic, A., Pietra, G., Nienen, M., Blau, I.W., Hofmann, J., Na, I.K., Prinz, I., Koenecke, C., Hemmati, P., Babel, N., Arnold, R., Walter, J., Thurley, K., Mashreghi, M.F., Messerle, M. and Romagnani, C.
Nature Immunology 19
(5): 453-463.
May 2018
Histone deacetylase 1 controls CD4(+) T cell trafficking in autoinflammatory diseases.
Hamminger, P., Marchetti, L., Preglej, T., Platzer, R., Zhu, C., Kamnev, A., Rica, R., Stolz, V., Sandner, L., Alteneder, M., Kaba, E., Waltenberger, D., Huppa, J.B., Trauner, M., Bock, C., Lyck, R., Bauer, J., Dupré, L., Seiser, C., Boucheron, N., Engelhardt, B. and Ellmeier, W.
Journal of Autoimmunity 119
: 102610.
May 2021
Promoter crosstalk effects on gene expression.
Hampf, M. and Gossen, M.
Journal of Molecular Biology 365
(4): 911-920.
26 January 2007
A protocol for combined Photinus and Renilla luciferase quantification compatible with protein assays.
Hampf, M. and Gossen, M.
Analytical Biochemistry 356
(1): 94-99.
1 September 2006
Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
Han, Y., Lindner, S., Bei, Y., Garcia, H.D., Timme, N., Althoff, K., Odersky, A., Schramm, A., Lissat, A., Künkele, A., Deubzer, H.E., Eggert, A., Schulte, J.H. and Henssen, A.G.
Cancer Letters 445
: 24-33.
31 March 2019
Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash, A.M., Kappel, L.W., Yim, N.L., Nejat, R.A., Goldberg, G.L., Smith, O.M., Rao, U.K., Dykstra, L., Na, I.K., Holland, A.M., Dudakov, J.A., Liu, C., Murphy, G.F., Leonard, W.J., Heller, G. and van den Brink, M.R.M.
Blood 118
(2): 446-455.
14 July 2011
Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax.
Handrick, R., Ganswindt, U., Faltin, H., Goecke, B., Daniel, P.T., Budach, W., Belka, C. and Jendrossek, V.
Radiotherapy and Oncology 90
(3): 413-421.
March 2009
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
Hanna, J., Schütz, A., Zimmermann, F., Behlke, J., Sommer, T. and Heinemann, U.
Journal of Biological Chemistry 287
(11): 8633-8640.
9 March 2012
Characterization of the human P-type 6-phosphofructo-1-kinase gene promoter in neural cell lines.
Hannemann, A., Jandrig, B., Gaunitz, F., Eschrich, K. and Bigl, M.
Gene 345
(2): 237-247.
1 January 2005
The dipole moment of the electron carrier adrenodoxin is not critical for redox partner interaction and electron transfer.
Hannemann, F., Guyot, A., Zoellner, A., Mueller, J.J., Heinemann, U. and Bernhardt, R.
Journal of Inorganic Biochemistry 103
(7): 997-1004.
July 2009
A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4.
Hansen, M.T., Forst, B., Cremers, N., Quagliata, L., Ambartsumian, N., Grum-Schwensen, B., Klingelhoefer, J., Abdul-Al, A., Herrmann, P., Osterland, M., Stein, U., Nielsen, G.H., Scherer, P.E., Lukanidin, E., Sleeman, J.P. and Grigorian, M.
Oncogene 34
(4): 424-435.
22 January 2015
GOPHER: Generator Of Probes for capture Hi-C Experiments at high Resolution.
Hansen, P., Ali, S., Blau, H., Danis, D., Hecht, J., Kornak, U., Lupiáñez, D.G., Mundlos, S., Steinhaus, R. and Robinson, P.N.
BMC Genomics 20
(1): 40.
14 January 2019
Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion.
Hanssen, E., Dekiwadia, C., Riglar, D.T., Rug, M., Lemgruber, L., Cowman, A.F., Cyrklaff, M., Kudryashev, M., Frischknecht, F., Baum, J. and Ralph, S.A.
Cellular Microbiology 15
(9): 1457-1472.
September 2013
Information theoretic based segments for language identification.
Harbeck, S., Ohler, U., Noth, E. and Niemann, H.
Lecture Notes in Computer Science 1692
: 187-192.
1999
Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment.
Haremaki, T., Metzger, J.J., Rito, T., Ozair, M.Z., Etoc, F. and Brivanlou, A.H.
Nature Biotechnology 37
(10): 1198-1208.
October 2019
Comparison of the effect of orally administered soluble β-(1-3),(1-6)-D-glucan and of G-CSF on the recovery of murine hematopoiesis.
Harnack, U., Eckert, K., Fichtner, I. and Pecher, G.
In Vivo 24
(1): 59-63.
January 2010
Oral administration of a soluble 1-3, 1-6 beta-glucan during prophylactic survivin peptide vaccination diminishes growth of a B cell lymphoma in mice.
Harnack, U., Eckert, K., Fichtner, I. and Pecher, G.
International Immunopharmacology 9
(11): 1298-1303.
October 2009
Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis.
Harnack, C., Berger, H., Liu, L., Mollenkopf, H.J., Strowig, T. and Sigal, M.
Gut Microbes 15
(1): 2233689.
10 July 2023
A critical period of translational control during brain development at codon resolution.
Harnett, D., Ambrozkiewicz, M.C., Zinnall, U., Rusanova, A., Borisova, E., Drescher, A.N., Couce-Iglesias, M., Villamil, G., Dannenberg, R., Imami, K., Münster-Wandowski, A., Fauler, B., Mielke, T., Selbach, M., Landthaler, M., Spahn, C.M.T., Tarabykin, V., Ohler, U. and Kraushar, M.L.
Nature Structural & Molecular Biology 29
(12): 1277-1290.
December 2022
Genome-wide analysis of actively translated open reading frames using riboTaper/ORFquant.
Harnett, D., Meerdink, E., Calviello, L., Sydow, D. and Ohler, U.
Methods in Molecular Biology 2252
: 331-346.
2021
Mesothelial cell HIF1α expression is metabolically downregulated by metformin to prevent oncogenic tumor-stromal crosstalk.
Hart, P.C., Kenny, H.A., Grassl, N., Watters, K.M., Litchfield, L.M., Coscia, F., Blaženović, I., Ploetzky, L., Fiehn, O., Mann, M., Lengyel, E. and Romero, I.L.
Cell Reports 29
(12): 4086-4098.
17 December 2019
p53 terminates the regenerative fetal-like state after colitis-associated injury.
Hartl, K., Bayram, Ş., Wetzel, A., Harnack, C., Lin, M., Fischer, A.S., Liu, L., Beccacec, G., Mastrobuoni, G., Geisberger, S., Forbes, M., Monteiro, B.J.E., Macino, M., Flores, R.E., Engelmann, C., Mollenkopf, H.J., Schupp, M., Tacke, F., Sanders, A.D., Kempa, S., Berger, H. and Sigal, M.
Science Advances 10
(43): eadp8783.
25 October 2024
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A., Sieverling, L., Nadler-Holly, M., Ziehm, M., Toprak, U.H., Herrmann, C., Ishaque, N., Okonechnikov, K., Gartlgruber, M., Park, Y.G., Wecht, E.M., Savelyeva, L., Henrich, K.O., Rosswog, C., Fischer, M., Hero, B., Jones, D.T.W., Pfaff, E., Witt, O., Pfister, S.M., Volckmann, Ri., Koster, J., Kiesel, K., Rippe, K., Taschner-Mandl, S., Ambros, P., Brors, B., Selbach, M., Feuerbach, L. and Westermann, F.
Nature Communications 12
(1): 1269.
24 February 2021
Alternative splicing substantially diversifies the transcriptome during early photomorphogenesis and correlates with the energy availability in arabidopsis.
Hartmann, L., Drewe-Boss, P., Wiessner, T., Wagner, G., Geue, S., Lee, H.C., Obermueller, D.M., Kahles, A., Behr, J., Sinz, F.H., Raetsch, G. and Wachter, A.
Plant Cell 28
(11): 2715-2734.
November 2016
Paracrine and autocrine regulation of gene expression by Wnt-inhibitor Dickkopf in wild-type and mutant hepatocytes.
Hartung, N., Benary, U., Wolf, J. and Kofahl, B.
BMC Systems Biology 11
(1): 98.
13 October 2017
Insulin-like growth factor binding protein-2 (IGFBP2) is a key molecule in the MACC1-mediated platelet communication and metastasis of colorectal cancer cells.
Haschemi, R., Kobelt, D., Steinwarz, E., Schlesinger, M., Stein, U. and Bendas, G.
International Journal of Molecular Sciences 22
(22): 12195.
11 November 2021
Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-xL in a strictly caspase-3-dependent manner in human carcinoma cells.
Hasenjaeger, A., Gillissen, B., Mueller, A., Normand, G., Hemmati, P.G., Schuler, M., Doerken, B. and Daniel, P.T.
Oncogene 23
(26): 4523-4535.
3 June 2004
Common structural constituents confer IkappaB activity to NF-kappaB p105 and IkappaB/MAD-3.
Hatada, E.N., Naumann, M. and Scheidereit, C.
EMBO Journal 12
(7): 2781-2788.
July 1993
Cellular senescence predicts treatment outcome in metastasised colorectal cancer.
Haugstetter, A.M., Loddenkemper, C., Lenze, D., Groene, J., Standfuss, C., Petersen, I., Doerken, B. and Schmitt, C.A.
British Journal of Cancer 103
(4): 505-509.
10 August 2010
Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V., Durrieu-Gaillard, S., Dumay-Odelot, H., Da Silva, D., Rey, C., Prochazkova, M., Roeder, R.G., Besser, D. and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107
(9): 4176-4181.
2 March 2010
Widely applicable, extended flow cytometric stem cell enumeration panel for quality control of advanced cellular products.
Haussmann, K., Streitz, M., Takvorian, A., Grund, J., Skenderi, Z., Tietze-Bürger, C., Movassaghi, K., Künkele, A., Blum, A. and Bullinger, L.
Scientific Reports 12
(1): 17995.
26 October 2022
An individual patient-data comparison of combined modality therapy and ABVD alone for patients with limited-stage Hodgkin lymphoma.
Hay, A.E., Klimm, B., Chen, B.E., Goergen, H., Shepherd, L.E., Fuchs, M., Gospodarowicz, M.K., Borchmann, P., Connors, J.M., Markova, J., Crump, M., Lohri, A., Winter, J.N., Doerken, B., Pearcey, R.G., Diehl, V., Horning, S.J., Eich, H.T., Engert, A. and Meyer, R.M.
Annals of Oncology 24
(12): 3065-3069.
December 2013
Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT.
Hayashida, N., Fujimoto, M., Tan, K., Prakasam, R., Shinkawa, T., Li, L., Ichikawa, H., Takii, R. and Nakai, A.
EMBO Journal 29
(20): 3459-3469.
20 October 2010
CD4+ T cell dependent B cell recovery and function after autologous hematopoietic stem cell transplantation.
Heck, C., Steiner, S., Kaebisch, E.M., Frentsch, M., Wittenbecher, F., Scheibenbogen, C., Hanitsch, L.G., Nogai, A., le Coutre, P., Bullinger, L., Blau, I.W. and Na, I.K.
Frontiers in Immunology 12
: 736137.
September 2021
Structure of a classical MHC class I molecule that binds "non-classical" ligands.
Hee, C.S., Gao, S., Loll, B., Miller, M.M., Uchanska-Ziegler, B., Daumke, O. and Ziegler, A.
PLoS Biology 8
(12): e1000557.
7 December 2010
Expression, purification and preliminary X-ray crystallographic analysis of the chicken MHC class I molecule YF1*7.1.
Hee, C.S., Gao, S., Miller, M.M., Goto, R.M., Ziegler, A., Daumke, O. and Uchanska-Ziegler, B.
Acta Crystallographica Section F 65
(Pt 4): 422-425.
1 April 2009
Alternate splicing of mouse fusin/CXC chemokine receptor-4: stromal cell-derived factor-1α is a ligand for both CXC chemokine receptor-4 isoforms.
Heesen, M., Berman, M.A., Höpken, U.E., Gerard, N.P. and Dorf, M.E.
Journal of Immunology 158
(8): 3561-3564.
15 April 1997
Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia.
Hegazy, A.N., Krönke, J., Angermair, S., Schwartz, S., Weidinger, C., Keller, U., Treskatsch, S., Siegmund, B. and Schneider, T.
BMC Infectious Diseases 22
(1): 537.
13 June 2022
Key factors regulating Plasmodium berghei sporozoite survival and transformation revealed by an automated visual assay.
Hegge, S., Kudryashev, M., Barniol, L. and Frischknecht, F.
FASEB Journal 24
(12): 5003-5012.
December 2010
Automated classification of Plasmodium sporozoite movement patterns reveals a shift towards productive motility during salivary gland infection.
Hegge, S., Kudryashev, M., Smith, A. and Frischknecht, F.
Biotechnology Journal 4
(6): 903-913.
June 2009
Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants.
Hehlmann, R., Lauseker, M., Saußele, S., Pfirrmann, M., Krause, S., Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Heim, D., Brümmendorf, T.H., Fabarius, A., Haferlach, C., Schlegelberger, B., Müller, M.C., Jeromin, S., Proetel, U., Kohlbrenner, K., Voskanyan, A., Rinaldetti, S., Seifarth, W., Spieß, B., Balleisen, L., Goebeler, M.C., Hänel, M., Ho, A., Dengler, J., Falge, C., Kanz, L., Kremers, S., Burchert, A., Kneba, M., Stegelmann, F., Köhne, C.A., Lindemann, H.W., Waller, C.F., Pfreundschuh, M., Spiekermann, K., Berdel, W.E., Müller, L., Edinger, M., Mayer, J., Beelen, D.W., Bentz, M., Link, H., Hertenstein, B., Fuchs, R., Wernli, M., Schlegel, F., Schlag, R., de Wit, M., Trümper, L., Hebart, H., Hahn, M., Thomalla, J., Scheid, C., Schafhausen, P., Verbeek, W., Eckart, M.J., Gassmann, W., Pezzutto, A., Schenk, M., Brossart, P., Geer, T., Bildat, S., Schäfer, E., Hochhaus, A. and Hasford, J.
Leukemia 31
(11): 2398-2406.
November 2017
High-risk additional chromosomal abnormalities at low blast counts herald death by CML.
Hehlmann, R., Voskanyan, A., Lauseker, M., Pfirrmann, M., Kalmanti, L., Rinaldetti, S., Kohlbrenner, K., Haferlach, C., Schlegelberger, B., Fabarius, A., Seifarth, W., Spieß, B., Wuchter, P., Krause, S., Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Burchert, A., Brümmendorf, T.H., Hasford, J., Hochhaus, A., Saußele, S. and Baccarani, M.
Leukemia 34
(8): 2074-2086.
August 2020
Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Heidenreich, S., Witte, N., Weber, P., Goehring, I., Tolkachov, A., von Loeffelholz, C., Döcke, S., Bauer, M., Stockmann, M., Pfeiffer, A.F.H., Birkenfeld, A.L., Pietzke, M., Kempa, S., Muenzner, M. and Schupp, M.
Nature Communications 8
(1): 384.
30 August 2017
The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Heider, M., Eichner, R., Stroh, J., Morath, V., Kuisl, A., Zecha, J., Lawatscheck, J., Baek, K., Garz, A.K., Rudelius, M., Deuschle, F.C., Keller, U., Lemeer, S., Verbeek, M., Götze, K.S., Skerra, A., Weber, W.A., Buchner, J., Schulman, B.A., Kuster, B., Fernández-Sáiz, V. and Bassermann, F.
Molecular Cell 81
(6): 1170-1186.
18 March 2021
Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
Heinig, K., Gätjen, M., Grau, M., Stache, V., Anagnostopoulos, I., Gerlach, K., Niesner, R.A., Cseresnyes, Z., Hauser, A.E., Lenz, P., Hehlgans, T., Brink, R., Westermann, J., Dörken, B., Lipp, M., Lenz, G., Rehm, A. and Höpken, U.E.
Cancer Discovery 4
: 1448-1465.
December 2014
Diagnostic work-up of rectal bleeding in general practice.
Heintze, C., Matysiak-Klose, D., Kroehn, T., Wolf, U., Brand, A., Meisner, C., Fischer, I., Wehrmeyer, H. and Braun, V.
British Journal of General Practice 55
(510): 14-19.
1 January 2005
The interaction domain of the redox protein adrenodoxin is mandatory for binding of the electron acceptor CYP11A1, but is not required for binding of the electron donor adrenodoxin reductase.
Heinz, A., Hannemann, F., Mueller, J.J., Heinemann, U. and Bernhardt, R.
Biochemical and Biophysical Research Communications 338
(9): 491-498.
29 August 2005
ssHMM: extracting intuitive sequence-structure motifs from high-throughput RNA-binding protein data.
Heller, D., Krestel, R., Ohler, U., Vingron, M. and Marsico, A.
Nucleic Acids Research 45
(19): 11004-11018.
2 November 2017
Environmental constraints guide migration of malaria parasites during transmission.
Hellmann, J.K., Münter, S., Kudryashev, M., Schulz, S., Heiss, K., Müller, A.K., Matuschewski, K., Spatz, J.P., Schwarz, U.S. and Frischknecht, F.
PLoS Pathogens 7
(6): e1002080.
16 June 2011
DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens.
Hellmeier, J., Platzer, R., Eklund, A.S., Schlichthaerle, T., Karner, A., Motsch, V., Schneider, M.C., Kurz, E., Bamieh, V., Brameshuber, M., Preiner, J., Jungmann, R., Stockinger, H., Schütz, G.J., Huppa, J.B. and Sevcsik, E.
Proceedings of the National Academy of Sciences of the United States of America 118
(4): e2016857118.
26 January 2021
A DNA origami-based biointerface to interrogate the spatial requirements for sensitized T-Cell antigen recognition.
Hellmeier, J., Platzer, R., Huppa, J.B. and Sevcsik, E.
Methods in Molecular Biology 2654
: 277-302.
28 April 2023
Strategies for the site-specific decoration of DNA origami nanostructures with functionally intact proteins.
Hellmeier, J., Platzer, R., Mühlgrabner, V., Schneider, M.C., Kurz, E., Schütz, G.J., Huppa, J.B. and Sevcsik, E.
ACS Nano 15
(9): 15057-15068.
28 September 2021
Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
Hellmuth, K., Grosskopf, S., Lum, C.T., Wuertele, M., Roeder, N., von Kries, J.P., Rosario, M., Rademann, J. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 105
(20): 7275-7280.
20 May 2008
A comparison of nine machine learning mutagenicity models and their application for predicting pyrrolizidine alkaloids.
Helma, C., Schöning, V., Drewe, J. and Boss, P.
Frontiers in Pharmacology 12
: 708050.
22 July 2021
Recurrent chromosomal aberrations in INK4a/ARF defective primary lymphomas predict drug responses in vivo.
Helmrich, A., Lee, S., O'Brien, P., Doerken, B., Lowe, S.W., Schroeck, E. and Schmitt, C.A.
Oncogene 24
: 4174-4182.
1 January 2005
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Helmsauer, K., Valieva, M.E., Ali, S., Chamorro Gonzalez, R., Schöpflin, R., Röefzaad, C., Bei, Y., Dorado Garcia, H., Rodriguez-Fos, E., Puiggròs, M., Kasack, K., Haase, K., Keskeny, C., Chen, C.Y., Kuschel, L.P., Euskirchen, P., Heinrich, V., Robson, M.I., Rosswog, C., Toedling, J., Szymansky, A., Hertwig, F., Fischer, M., Torrents, D., Eggert, A., Schulte, J.H., Mundlos, S., Henssen, A.G. and Koche, R.P.
Nature Communications 11
(1): 5823.
16 November 2020
Bak functionally complements for loss of Bax during p14(ARF)-induced mitochondrial apoptosis in human cancer cells.
Hemmati, P.G., Guener, D., Gillissen, B., Wendt, J., von Haefen, C., Chinnadurai, G., Doerken, B. and Daniel, P.T.
Oncogene 25
(50): 6582-6594.
26 October 2006
Systematic genetic dissection of p14(ARF)-mediated mitochondrial cell death signaling reveals a key role for p21(CDKN1) and the BH3-only protein Puma/bbc3.
Hemmati, P.G., Mueer, A., Gillissen, B., Overkamp, T., Milojkovic, A., Wendt, J., Doerken, B. and Daniel, P.T.
Journal of Molecular Medicine 88
(6): 609-622.
June 2010
Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.
Hemmati, P.G., Normand, G., Gillissen, B., Wendt, J., Doerken, B. and Daniel, P.T.
Oncogene 27
(53): 6707-6719.
4 December 2008
Loss of p21 disrupts p14ARF-induced G1 cell cycle arrest but augments p14ARF-induced apoptosis in human carcinoma cells.
Hemmati, P.G., Normand, G., Verdoodt, B., von Haefen, C., Hasenjaeger, A., Guener, D., Wendt, J., Doerken, B. and Daniel, P.T.
Oncogene 24
(25): 4114-4128.
1 January 2005
Cytogenetic risk grouping by the monosomal karyotype classification is superior in predicting the outcome of acute myeloid leukemia undergoing allogeneic stem cell transplantation in complete remission.
Hemmati, P.G., Schulze-Luckow, A., Terwey, T.H., le Coutre, P., Vuong, L.G., Doerken, B. and Arnold, R.
European Journal of Haematology 92
(2): 102-110.
February 2014
Reduced intensity conditioning prior to allogeneic stem cell transplantation in first complete remission is effective in patients with acute myeloid leukemia and an intermediate-risk karyotype.
Hemmati, P.G., Terwey, T.H., Massenkeil, G., le Coutre, P., Vuong, L.G., Neuburger, S., Doerken, B. and Arnold, R.
International Journal of Hematology 91
(3): 436-445.
April 2010
Allogeneic stem cell transplantation for refractory acute myeloid leukemia: a single center analysis of long-term outcome.
Hemmati, P.G., Terwey, T.H., Na, I.K., Jehn, C.F., le Coutre, P., Vuong, L.G., Doerken, B. and Arnold, R.
European Journal of Haematology 95
(6): 498-506.
December 2015
A modified EBMT risk score predicts the outcome of patients with acute myeloid leukemia receiving allogeneic stem cell transplants.
Hemmati, P.G., Terwey, T.H., le Coutre, P., Vuong, L.G., Massenkeil, G., Doerken, B. and Arnold, R.
European Journal of Haematology 86
(4): 305-316.
April 2011
Adenovirus-mediated overexpression of p14ARF induces p53 and Bax-independent apoptosis.
Hemmati, P.G., Gillissen, B., von Haefen, C., Wendt, J., Staerck, L., Guener, D., Doerken, B. and Daniel, P.T.
Oncogene 21
(20): 3149-3161.
9 May 2002
Impact of early remission by induction therapy on allogeneic stem cell transplantation for acute myeloid leukemia with an intermediate risk karyotype in first complete remission.
Hemmati, P.G., Terwey, T.H., Na, I.K., le Coutre, P., Jehn, C.F., Vuong, L.G., Dörken, B. and Arnold, R.
European Journal of Haematology 94
(5): 431-438.
May 2015
Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation.
Hemmati, P.G., Vuong, L.G., Terwey, T.H., Jehn, C.F., Le Coutre, P., Penack, O., Na, I.K., Dörken, B. and Arnold, R.
European Journal of Haematology 98
(2): 160-168.
February 2017
Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative.
Hendriks, H.R., Govaerts, A.S., Fichtner, I., Burtles, S., Westwell, A.D. and Peters, G.J.
British Journal of Cancer 117
(2): 195-202.
11 July 2017
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Henke, N., Schmidt-Ullrich, R., Dechend, R., Park, J.K., Qadri, F., Wellner, M., Obst, M., Gross, V., Dietz, R., Luft, F.C., Scheidereit, C. and Mueller, D.N.
Circulation Research 101
(3): 268-276.
3 August 2007
Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature.
Henne, W.M., Kent, H.M., Ford, M.G.J., Hegde, B.G., Daumke, O., Butler, P.J.G., Mittal, R., Langen, R., Evans, P.R. and McMahon, H.T.
Structure 15
(7): 839-52.
July 2007
HEK293-based production platform for γ-retroviral (SIN-) vectors: application for safe and efficient transfer of COL7A1 cDNA.
Hennig, K., Raasch, L., Kolbe, C., Weidner, S., Leisegang, M., Uckert, W., Titeux, M., Hovnanian, A., Kuehlcke, K. and Loew, R.
Human Gene Therapy Clinical Development 25
(4): 218-228.
December 2014
CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: Modulation by FTY720.
Henning, G., Ohl, H., Junt, T., Reiterer, P., Brinkmann, V., Nakano, H., Hohenberger, W., Lipp, M. and Foerster, R.
Journal of Experimental Medicine 194
(12): 1875-1881.
17 December 2001
CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programs in neuroblastoma cells.
Henrich, K.O., Bauer, T., Schulte, J., Ehemann, V., Deubzer, H., Gogolin, S., Muth, D., Fischer, M., Benner, A., König, R., Schwab, M. and Westermann, F.
Cancer Research 71
(8): 3142-3151.
15 April 2011
Transplantation of human acute myeloid leukemia (AML) cells in immunodeficient mice reveals altered cell surface phenotypes and expression of human endothelial markers.
Henschler, R., Goettig, S., Junghahn, I., Bug, G., Seifried, E., Mueller, A.M. and Fichtner, I.
Leukemia Research 29
(10): 1191-1199.
1 January 2005
Targeting MYCN-driven transcription by BET-bromodomain inhibition.
Henssen, A., Althoff, K., Odersky, A., Beckers, A., Koche, R., Speleman, F., Schäfers, S., Bell, E., Nortmeyer, M., Westermann, F., De Preter, K., Florin, A., Heukamp, L., Spruessel, A., Astrahanseff, K., Lindner, S., Sadowski, N., Schramm, A., Astorgues-Xerri, L., Riveiro, M.E., Eggert, A., Cvitkovic, E. and Schulte, J.H.
Clinical Cancer Research 22
(10): 2470-2481.
May 2016
BET bromodomain protein inhibition is a therapeutic option for medulloblastoma.
Henssen, A., Thor, T., Odersky, A., Heukamp, L., El-Hindy, N., Beckers, A., Speleman, F., Althoff, K., Schäfers, S., Schramm, A., Sure, U., Fleischhack, G., Eggert, A. and Schulte, J.H.
Oncotarget 4
(11): 2080-2095.
November 2013
Cytoarchitecture and probability maps of the human medial orbitofrontal cortex.
Henssen, A., Zilles, K., Palomero-Gallagher, N., Schleicher, A., Mohlberg, H., Gerboga, F., Eickhoff, S.B., Bludau, S. and Amunts, K.
Cortex 75
: 87-112.
February 2016
Genomic DNA transposition induced by human PGBD5.
Henssen, A.G., Henaff, E., Jiang, E., Eisenberg, A.R., Carson, J.R., Villasante, C.M., Ray, M., Still, E., Burns, M., Gandara, J., Feschotte, C., Mason, C.E. and Kentsis, A.
eLife 4
: e10565.
25 September 2015
Forward genetic screen of human transposase genomic rearrangements.
Henssen, A.G., Jiang, E., Zhuang, J., Pinello, L., Socci, N.D., Koche, R., Gonen, M., Villasante, C.M., Armstrong, S.A., Bauer, D.E., Weng, Z. and Kentsis, A.
BMC Genomics 17
: 548.
4 August 2016
PGBD5 promotes site-specific oncogenic mutations in human tumors.
Henssen, A.G., Koche, R., Zhuang, J., Jiang, E., Reed, C., Eisenberg, A., Still, E., MacArthur, I.C., Rodriguez-Fos, E., Gonzalez, S., Puiggròs, M., Blackford, A.N., Mason, C.E., de Stanchina, E., Gönen, M., Emde, A.K., Shah, M., Arora, K., Reeves, C., Socci, N.D., Perlman, E., Antonescu, C.R., Roberts, C.W.M., Steen, H., Mullen, E., Jackson, S.P., Torrents, D., Weng, Z., Armstrong, S.A. and Kentsis, A.
Nature Genetics 49
(7): 1005-1014.
July 2017
Targeting tachykinin receptors in neuroblastoma.
Henssen, A.G., Odersky, A., Szymansky, A., Seiler, M., Althoff, K., Beckers, A., Speleman, F., Schäfers, S., De Preter, K., Astrahanseff, K., Struck, J., Schramm, A., Eggert, A., Bergmann, A. and Schulte, J.H.
Oncotarget 8
(1): 430-443.
3 January 2017
Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.
Henssen, A.G., Reed, C., Jiang, E., Garcia, H.D., von Stebut, J., MacArthur, I.C., Hundsdoerfer, P., Kim, J.H., de Stanchina, E., Kuwahara, Y., Hosoi, H., Ganem, N.J., Dela Cruz, F., Kung, A.L., Schulte, J.H., Petrini, J.H. and Kentsis, A.
Science Translational Medicine 9
(414): eaam9078.
1 November 2017
A role for GPx3 in activity of normal and leukemia stem cells.
Herault, O., Hope, K.J., Deneault, E., Mayotte, N., Chagraoui, J., Wilhelm, B.T., Cellot, S., Sauvageau, M., Andrade-Navarro, M.A., Hebert, J. and Sauvageau, G.
Journal of Experimental Medicine 209
(5): 895-901.
7 May 2012
Relation between stressful life events, neuropeptides and cytokines: results from the LISA birth cohort study.
Herberth, G., Weber, A., Roeder, S., Elvers, H.D., Kraemer, U., Schins, R.P., Diez, U., Borte, M., Heinrich, J., Schaefer, T., Herbarth, O. and Lehmann, I.
Pediatric Allergy and Immunology 19
(8): 722-729.
December 2008
Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.
Herda, S., Heimann, A., Obermayer, B., Ciraolo, E., Althoff, S., Ruß, J., Grunert, C., Busse, A., Bullinger, L., Pezzutto, A., Blankenstein, T., Beule, D. and Na, I.K.
International Journal of Cancer 148
(12): 3097-3110.
15 June 2021
CXCR4-targeted PET imaging of central nervous system B-cell lymphoma.
Herhaus, P., Lipkova, J., Lammer, F., Yakushev, I., Vag, T., Slotta-Huspenina, J., Habringer, S., Lapa, C., Pukrop, T., Hellwig, D., Wiestler, B., Buck, A.K., Deckert, M., Wester, H.J., Bassermann, F., Schwaiger, M., Weber, W.A., Menze, B. and Keller, U.
Journal of Nuclear Medicine 61
(12): 1765-1771.
1 December 2020
Angiotensin-(1-7) stimulates hematopoietic progenitor cells in vitro and in vivo.
Heringer-Walther, S., Eckert, K., Schumacher, S.M., Uharek, L., Wulf-Goldenberg, A., Gembardt, F., Fichtner, I., Schultheiss, H.P., Rodgers, K. and Walther, T.
Haematologica 94
(6): 857-860.
June 2009
Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.
Herlan, M., Vogel, F., Boernhovd, C., Neupert, W. and Reichert, A.S.
Journal of Biological Chemistry 278
(30): 27781-27788.
1 January 2003
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca, P., Vonficht, D., Schnell, A., Uckelmann, H.J., Bollhagen, A., Mahmoud, M.A.A., Landua, S.L., van der Salm, E., Trautmann, C., Raffel, S., Grünschläger, F., Lutz, R., Ghosh, M., Renders, S., Correia, N., Donato, E., Dixon, K.O., Hirche, C., Andresen, C., Robens, Cl., Werner, P.S., Boch, T., Eisel, D., Osen, W., Pilz, F., Przybylla, A., Klein, C., Buchholz, F., Milsom, M.D., Essers, M.A.G., Eichmüller, S.B., Hofmann, W.K., Nowak, D., Hübschmann, D., Hundemer, M., Thiede, C., Bullinger, L., Müller-Tidow, C., Armstrong, S.A., Trumpp, A., Kuchroo, V.K. and Haas, S.
Cell Stem Cell 29
(5): 760-775.
5 May 2022
Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study.
Hernández-Sánchez, A., González, T., Sobas, M., Sträng, E., Castellani, G., Abáigar, M., Valk, P.J.M., Villaverde Ramiro, Á., Benner, A., Metzeler, K.H., Azibeiro, R., Tettero, J.M., Martínez-López, J., Pratcorona, M., Martínez Elicegui, J., Mills, K.I., Thiede, C., Sanz, G., Döhner, K., Heuser, M., Haferlach, T., Turki, A.T., Reinhardt, D., Schulze-Rath, R., Barbus, M., Hernández-Rivas, J.M., Huntly, B., Ossenkoppele, G., Döhner, H. and Bullinger, L.
Leukemia 38
(9): 1929-1937.
September 2024
Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
Herrlinger, U., Tzaridis, T., Mack, F., Steinbach, J.P., Schlegel, U., Sabel, M., Hau, P., Kortmann, R.D., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Bähr, O., Uhl, M., Seidel, C., Tabatabai, G., Kowalski, T., Ringel, F., Schmidt-Graf, F., Suchorska, B., Brehmer, S., Weyerbrock, A., Renovanz, M., Bullinger, L., Galldiks, N., Vajkoczy, P., Misch, M., Vatter, H., Stuplich, M., Schäfer, N., Kebir, S., Weller, J., Schaub, C., Stummer, W., Tonn, J.C., Simon, M., Keil, V.C., Nelles, M., Urbach, H., Coenen, M., Wick, W., Weller, M., Fimmers, R., Schmid, M., Hattingen, E., Pietsch, T., Coch, C. and Glas, M.
Lancet 393
(10172): 678-688.
16 February 2019
CTLA4 promotes Tyk2-STAT3 dependent B-cell oncogenecity.
Herrmann, A., Lahtz, C., Nagao, T., Song, J.Y., Chan, W.C., Lee, H., Yue, C., Look, T., Muelfarth, R., Li, W., Jenkins, K., Williams, J., Budde, L.E., Forman, S.J., Kwak, L.W., Blankenstein, T. and Yu, H.
Cancer Research 77
(18): 5118-5128.
15 September 2017
Transitory dasatinib-resistant states in KIT(mut) t(8;21) acute myeloid leukemia cells correlate with altered KIT expression.
Herrmann, M.D., Lennerz, J.K., Bullinger, L., Bartholomae, S., Holzmann, K., Westhoff, M.A., Corbacioglu, S. and Debatin, K.M.
Experimental Hematology 42
(2): 90-100.
February 2014
DNA damage signaling instructs polyploid macrophage fate in granulomas.
Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Münke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S., Sieweke, M.H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M.M., Voll, R.E., Deshmukh, S.D., Prinz, M., Goldmann, T., Hölscher, C., Hauser, A.E., Lopez-Contreras, A.J., Grün, D., Gorgoulis, V., Diefenbach, A., Henneke, P. and Triantafyllopoulou, A.
Cell 167
(5): 1264-1280.
17 November 2016
Detection of signature volatiles for cariogenic microorganisms.
Hertel, M., Preissner, R., Gillissen, B., Schmidt-Westhausen, A.M., Paris, S. and Preissner, S.
European Journal of Clinical Microbiology & Infectious Diseases 35
(2): 235-244.
February 2016
Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair.
Herzig, J.K., Bullinger, L., Tasdogan, A., Zimmermann, P., Schlegel, M., Teleanu, V., Weber, D., Rücker, F.G., Paschka, P., Dolnik, A., Schneider, E., Kuchenbauer, F., Heidel, F.H., Buske, C., Döhner, H., Döhner, K. and Gaidzik, V.I.
Oncotarget 8
(56): 95038-95053.
10 November 2017
A phase II trial to evaluate the combination of pixantrone and obinutuzumab for patients with relapsed aggressive lymphoma: Final results of the prospective, multicentre GOAL trial.
Hess, G., Hüttmann, A., Witzens-Harig, M., Dreyling, M.H., Keller, U., Marks, R., Ernst, T., Pott, C., Viardot, A., Frontzek, F., Trautmann, M., Ruckes, C., Deuster, O., Rosenwald, A., Theobald, M. and Lenz, G.
British Journal of Haematology 198
(3): 482-491.
1 April 2022
Final results of a phase I/II trial of the combination Bendamustine and Rituximab with Temsirolimus (BeRT) in relapsed mantle cell lymphoma and follicular lymphoma.
Hess, G., Wagner, K., Keller, U., La Rosee, P., Atta, J., Hübel, K., Lerchenmueller, C., Schoendube, D., Witzens-Harig, M., Ruckes, C., Medler, C., van Oordt, C., Klapper, W., Theobald, M. and Dreyling, M.
HemaSphere 4
(3): e398.
June 2020
Partitioned learning of deep Boltzmann machines for SNP data.
Hess, M., Lenz, S., Blätte, T.J., Bullinger, L. and Binder, H.
Bioinformatics 33
(20): 3173-3180.
October 2017
Vaccine-instructed intratumoral IFN-γ enables regression of autochthonous mouse prostate cancer in allogeneic T cell transplantation.
Hess Michelini, R., Manzo, T., Sturmheit, T., Basso, V., Rocchi, M., Freschi, M., Listopad, J.J., Blankenstein, T., Bellone, M. and Mondino, A.
Cancer Research 73
(15): 4641-4652.
1 August 2013
Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
Hessenberger, M., Zerbes, R.M., Rampelt, H., Kunz, S., Xavier, A.H., Purfürst, B., Lilie, H., Pfanner, N., van der Laan, M. and Daumke, O.
Nature Communications 8
: 15258.
31 May 2017
Interplay of cadherin-mediated cell adhesion and canonical wnt signaling.
Heuberger, J. and Birchmeier, W.
Cold Spring Harbor Perspectives in Biology 2
(2): a002915.
February 2010
Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J., Kosel, F., Qi, J., Grossmann, K.S., Rajewsky, K. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 111
(9): 3472-3477.
4 March 2014
High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J., Grinat, J., Kosel, F., Liu, L., Kunz, S., Vidal, R.O., Keil, M., Haybaeck, J., Robine, S., Louvard, D., Regenbrecht, C., Sporbert, A., Sauer, S., von Eyss, B., Sigal, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 118
(22): e2019699118.
1 June 2021
A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis.
Heuberger, J., Hill, U., Förster, S., Zimmermann, K., Malchin, V., Kühl, A.A., Stein, U., Vieth, M., Birchmeier, W. and Leutz, A.
Life Science Alliance 2
(1): e201800173.
February 2019
Epithelial response to IFN-γ promotes SARS-CoV-2 infection.
Heuberger, J., Trimpert, J., Vladimirova, D., Goosmann, C., Lin, M., Schmuck, R., Mollenkopf, H.J., Brinkmann, V., Tacke, F., Osterrieder, N. and Sigal, M.
EMBO Molecular Medicine 13
(4): e13191.
9 April 2021
Posttransplantation MRD monitoring in patients with AML by next-generation sequencing using DTA and non-DTA mutations.
Heuser, M., Heida, B., Büttner, K., Wienecke, C.P., Teich, K., Funke, C., Brandes, M., Klement, P., Liebich, A., Wichmann, M., Neziri, B., Chaturvedi, A., Kloos, A., Mintzas, K., Gaidzik, V.I., Paschka, P., Bullinger, L., Fiedler, W., Heim, A., Puppe, W., Krauter, J., Döhner, K., Döhner, H., Ganser, A., Stadler, M., Hambach, L., Gabdoulline, R. and Thol, F.
Blood Advances 5
(9): 2294-2304.
11 May 2021
SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Heynen, G.J.J.E., Baumgartner, F., Heider, M., Patra, U., Holz, M., Braune, J., Kaiser, M., Schäffer, I., Bamopoulos, S.A., Ramberger, E., Murgai, A., Ng, Y.L.D., Demel, U.M., Laue, D., Liebig, S., Krüger, J., Janz, M., Nogai, A., Schick, M., Mertins, P., Müller, S., Bassermann, F., Krönke, J., Keller, U. and Wirth, M.
Blood Advances 7
(4): 469-481.
28 February 2023
Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors.
Heynen, G.J.J.E., Lisek, K., Vogel, R., Wulf-Goldenberg, A., Alcaniz, J., Montaudon, E., Marangoni, E. and Birchmeier, W.
Breast Cancer Research 24
(1): 23.
1 April 2022
Codon bias confers stability to human mRNAs.
Hia, F., Yang, S.F., Shichino, Y., Yoshinaga, M., Murakawa, Y., Vandenbon, A., Fukao, A., Fujiwara, T., Landthaler, M., Natsume, T., Adachi, S., Iwasaki, S. and Takeuchi, O.
EMBO Reports 20
(11): e48220.
5 November 2019
Pangenome graph construction from genome alignments with Minigraph-Cactus.
Hickey, G., Monlong, J., Ebler, J., Novak, A.M., Eizenga, J.M., Gao, Y., Marschall, T., Li, H. and Paten, B.
Nature Biotechnology 42
(4): 663-673.
April 2024
Identifying prognostic SNPs in clinical cohorts: complementing univariate ynalyses by resampling and multivariable modeling.
Hieke, S., Benner, A., Schlenk, R.F., Schumacher, M., Bullinger, L. and Binder, H.
PLoS ONE 11
(5): e0155226.
May 2016
Integrating multiple molecular sources into a clinical risk prediction signature by extracting complementary information.
Hieke, S., Benner, A., Schlenl, R.F., Schumacher, M., Bullinger, L. and Binder, H.
BMC Bioinformatics 17
(1): 327.
30 August 2016
Intraoperative fresh-frozen plasma versus human albumin in craniofacial surgery - a pilot study comparing coagulation profiles in infants younger than 12 months.
Hildebrandt, B., Machotta, A., Riess, H., Kerner, S., Ahlers, O., Haberl, H., Doerken, B. and Kerner, T.
Thrombosis and Haemostasis 98
(1): 172-7.
July 2007
Assessment of free light chains in the cerebrospinal fluid of patients with lymphomatous meningitis - a pilot study.
Hildebrandt, B., Mueller, C., Pezzutto, A., Daniel, P.T., Doerken, B. and Scholz, C.
BMC Cancer 7
: 185.
3 October 2007
Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: A phase II-study and historical comparison with the surgical approach.
Hildebrandt, B., Pech, M., Nicolaou, A., Langrehr, J.M., Kurcz, J., Bartels, B., Miersch, A., Felix, R., Neuhaus, P., Riess, H., Doerken, B. and Ricke, J.
BMC Cancer 7
: 69.
24 April 2007
Adjuvant chemotherapy with folinic acid and 5-fluorouracil in patients with locally advanced rectal cancer previously treated by preoperative radiochemotherapy and curative tumor resection.
Hildebrandt, B., Rau, B., Loeffel, J., Wust, P., Nicolaou, A., Gellermann, J., Le Coutre, P., Neuhaus, P., Felix, R., Wernecke, K.D., Doerken, B. and Riess, H.
International Journal of Colorectal Disease 21
(6): 582-589.
September 2006
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.
Hill, T.P., Spaeter, D., Taketo, M.M., Birchmeier, W. and Hartmann, C.
Developmental Cell 8
(5): 727-738.
1 May 2005
Multiple roles of mesenchymal beta-catenin during murine limb patterning.
Hill, T.P., Taketo, M.M., Birchmeier, W. and Hartmann, C.
Development 133
(7): 1219-1229.
1 April 2006
Lung adenocarcinoma promotion by air pollutants.
Hill, W., Lim, E.L., Weeden, C.E., Lee, C., Augustine, M., Chen, K., Kuan, F.C., Marongiu, F., Evans, E.J., Moore, D.A., Rodrigues, F.S., Pich, O., Bakker, B., Cha, H., Myers, R., van Maldegem, F., Boumelha, J., Veeriah, S., Rowan, A., Naceur-Lombardelli, C., Karasaki, T., Sivakumar, M., De, S., Caswell, D.R., Nagano, A., Black, J.R.M., Martínez-Ruiz, C., Ryu, M.H., Huff, R.D., Li, S., Favé, M.J., Magness, A., Suárez-Bonnet, A., Priestnall, S.L., Lüchtenborg, M., Lavelle, K., Pethick, J., Hardy, S., McRonald, F.E., Lin, M.H., Troccoli, C.I., Ghosh, M., Miller, Y.E., Merrick, D.T., Keith, R.L., Al Bakir, M., Bailey, C., Hill, M.S., Saal, L.H., Chen, Y., George, A.M., Abbosh, C., Kanu, N., Lee, S.H., McGranahan, N., Berg, C.D., Sasieni, P., Houlston, R., Turnbull, C., Lam, S., Awadalla, P., Grönroos, E., Downward, J., Jacks, T., Carlsten, C., Malanchi, I., Hackshaw, A., Litchfield, K., DeGregori, J., Jamal-Hanjani, M. and Swanton, C.
Nature 616
(7955): 159-167.
6 April 2023
Evaluating the impact of genetic and epigenetic aberrations on survival and response in acute myeloid leukemia patients receiving epigenetic therapy.
Hiller, J.K., Schmoor, C., Gaidzik, V.I., Schmidt-Salzmann, C., Yalcin, A., Abdelkarim, M., Blagitko-Dorfs, N., Döhner, K., Bullinger, L., Duyster, J., Lübbert, M. and Hackanson, B.
Annals of Hematology 96
(4): 559-565.
April 2017
Construction of whole genomes from scaffolds using single cell strand-seq data.
Hills, M., Falconer, E., O'Neill, K., Sanders, A.D., Howe, K., Guryev, V. and Lansdorp, P.M.
International Journal of Molecular Sciences 22
(7): 3617.
1 April 2021
Signal-responsiveness of Ikappa B kinases is determined by Cdc37-assisted transient interaction with Hsp90.
Hinz, M., Broemer, M., Coel Arslan, S., Otto, A., Mueller, E.C., Dettmer, R. and Scheidereit, C.
Journal of Biological Chemistry 282
(44): 32311-32319.
2 November 2007
Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M., Lemke, P., Anagnostopoulos, I., Hacker, C., Krappmann, D., Mathas, S., Doerken, B., Zenke, M., Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196
(5): 605-617.
2 September 2002
Striking back at the activator: how IkappaB kinase terminates antigen receptor responses.
Hinz, M. and Scheidereit, C.
Science's STKE Signal Transduction Knowledge Environment 384
: pe19.
1 May 2007
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz, M., Stilmann, M., Coel Arslan, S., Khanna, K.K., Dittmar, G. and Scheidereit, C.
Molecular Cell 40
(1): 63-74.
8 October 2010
Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury.
Hinze, C., Kocks, C., Leiz, J., Karaiskos, N., Boltengagen, A., Cao, S., Skopnik, C.M., Klocke, J., Hardenberg, J.H., Stockmann, H., Gotthardt, I., Obermayer, B., Haghverdi, L., Wyler, E., Landthaler, M., Bachmann, S., Hocke, A.C., Corman, V., Busch, J., Schneider, W., Himmerkus, N., Bleich, M., Eckardt, K.U., Enghard, P., Rajewsky, N. and Schmidt-Ott, K.M.
Genome Medicine 14
(1): 103.
9 September 2022
Expanding the map of protein-RNA interaction sites via cell fusion followed by PAR-CLIP.
Hinze, F., Drewe-Boss, P., Milek, M., Ohler, U., Landthaler, M. and Gotthardt, M.
RNA Biology 15
(3): 359-368.
4 March 2018
A public health antibody screening indicates a 6-fold higher SARS-CoV-2 exposure rate than reported cases in children.
Hippich, M., Holthaus, L., Assfalg, R., Zapardiel Gonzalo, J.M., Kapfelsperger, H., Heigermoser, M., Haupt, F., Ewald, D.A., Welzhofer, T.C., Marcus, B.A., Heck, S., Koelln, A., Stock, J., Voss, F., Secchi, M., Piemonti, L., de la Rosa, K., Protzer, U., Boehmer, M., Achenbach, P., Lampasona, V., Bonifacio, E. and Ziegler, A.G.
Med 2
(2): 149-163.
12 February 2021
Alternative splicing variants of IkappaBbeta establish differential NF-kappaB signal responsiveness in human cells.
Hirano, F., Chung, M.R., Tanaka, H., Maruyama, N., Makino, I., Moore, D.D. and Scheidereit, C.
Molecular and Cellular Biology 18
(5): 2596-2607.
May 1998
Functional interference of Sp1 and NF-kappaB through the same DNA binding site.
Hirano, F., Tanaka, H., Hirano, Y., Hiramoto, M., Handa, H., Makino, I. and Scheidereit, C.
Molecular and Cellular Biology 18
(3): 1266-1274.
March 1998
Systemic virus infections differentially modulate cell cycle state and functionality of long-term hematopoietic stem cells in vivo.
Hirche, C., Frenz, T., Haas, S.F., Döring, M., Borst, K., Tegtmeyer, P.K., Brizic, I., Jordan, S., Keyser, K., Chhatbar, C., Pronk, E., Lin, S., Messerle, M., Jonjic, S., Falk, C.S., Trumpp, A., Essers, M.A.G. and Kalinke, U.
Cell Reports 19
(11): 2345-2356.
13 June 2017
Expression of multidrug resistance proteins (Mrps) in astrocytes of the mouse brain: a single cell rt-PCR study.
Hirrlinger, J., Moeller, H., Kirchhoff, F. and Dringen, R.
Neurochemical Research 30
(10): 1237-1244.
1 October 2005
Unraveling the transcriptional regulation of TWIST1 in limb development.
Hirsch, N., Eshel, R., Bar Yaacov, R., Shahar, T., Shmulevich, F., Dahan, I., Levaot, N., Kaplan, T., Lupiáñez, D.G. and Birnbaum, R..
PLoS Genetics 14
(10): e1007738.
29 October 2018
Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia.
Hirsch, S., Blätte, T.J., Grasedieck, S., Cocciardi, S., Rouhi, A., Jongen-Lavrencic, M., Paschka, P., Krönke, J., Gaidzik, V.I., Döhner, H., Schlenk, R.F., Kuchenbauer, F., Döhner, K., Dolnik, A. and Bullinger, L.
Haematologica 102
(12): 2039-2047.
December 2017
Clonal dominance defines metastatic dissemination in pancreatic cancer.
Ho, I.L., Li, C.Y., Wang, F., Zhao, L., Liu, J., Yen, E.Y., Dyke, C.A., Shah, R., Liu, Z., Çetin, A.O., Chu, Y., Citron, F., Attanasio, S., Corti, D., Darbaniyan, F., Del Poggetto, E., Loponte, S., Liu, J., Soeung, M., Chen, Z., Jiang, S., Jiang, H., Inoue, A., Gao, S., Deem, A., Feng, N., Ying, H., Kim, M., Giuliani, V., Genovese, G., Zhang, J., Futreal, A., Maitra, A., Heffernan, T., Wang, L., Do, K.A., Gargiulo, G., Draetta, G., Carugo, A., Lin, R. and Viale, A.
Science Advances 10
(11): eadd9342.
15 March 2024
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.
Ho, J.S., Di Tullio, F., Schwarz, M., Low, D., Incarnato, D., Gay, F., Tabaglio, T., Zhang, J.X., Wollmann, H., Chen, L., An, O., Chan, T.H.M., Hall Hickman, A., Zheng, S., Roudko, V., Chen, S., Karz, A., Ahmed, M., He, H.H., Greenbaum, B.D., Oliviero, S., Serresi, M., Gargiulo, G., Mann, K.M., Hernando, E., Mulholland, D., Marazzi, I., Wee, D.K.B. and Guccione, E.
eLife 10
: e59654.
2 June 2021
Vaccinations with tumor cells genetically engineered to produce different cytokines: effectivity not superior to a classical adjuvant.
Hock, H., Dorsch, M., Kunzendorf, U., Ueberla, K., Qin, Z., Diamantstein, T. and Blankenstein, T.
Cancer Research 53
(4): 714-716.
15 February 1993
Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma.
Hoellein, A., Fallahi, M., Schoeffmann, S., Steidle, S., Schaub, F.X., Rudelius, M., Laitinen, I., Nilsson, L., Goga, A., Peschel, C., Nilsson, J.A., Cleveland, J.L. and Keller, U.
Blood 124
(13): 2081-2090.
25 September 2014
Expression of a hypoglycosylated form of CD86 (B7-2) on human T cells with altered binding properties to CD28 and CTLA-4.
Hoellsberg, P., Scholz, C., Anderson, D.E., Greenfield, E.A., Kuchroo, V.K., Freeman, G.J. and Hafler, D.A.
Journal of Immunology 159
(10): 4799-4805.
15 November 1997
A novel recombinant bispecific single-chain antibody, bscWue-1 x CD3, induces T-cell-mediated cytotoxicity towards human multiple myeloma cells.
Hoenemann, D., Kufer, P., Rimpler, M.M., Chatterjee, M., Friedl, S., Riecher, F., Bommert, K., Doerken, B. and Bargou, R.C.
Leukemia 18
(3): 636-644.
1 January 2004
Small organic compounds enhance antigen-loading of class II MHC proteins by targeting the polymorphic P1 pocket.
Hoepner, S., Dickhaut, K., Hofstätter, M., Kraemer, H., Rueckerl, D., Soederhaell, J.A., Gupta, S., Marin-Esteban, V., Kuehne, R., Freund, C., Jung, G., Falk, K. and Roetzschke, O.
Journal of Biological Chemistry 281
(50): 38535-38542.
15 December 2006
Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
Hoffmann, J., Fichtner, I., Lemm, M., Lienau, P., Hess-Stumpp, H., Rotgeri, A., Hofmann, B. and Klar, U.
Neuro Oncology 11
(2): 158-166.
April 2009
A highly sensitive model for quantification of in vivo tumor angiogenesis induced by alginate-encapsulated tumor cells.
Hoffmann, J., Schirner, M., Menrad, A. and Schneider, M.R.
Cancer Research 57
(17): 3847-3851.
1 September 1997
Serial killing of tumor cells by cytotoxic T cells redirected with a CD19-/CD3-bispecific single-chain antibody construct.
Hoffmann, P., Hofmeister, R., Brischwein, K., Brandl, C., Crommer, S., Bargou, R., Itin, C., Prang, N. and Baeuerle, P.A.
International Journal of Cancer 115
: 98-104.
1 January 2005
Nontargeted identification of tracer incorporation in high-resolution mass spectrometry.
Hoffmann, F., Jaeger, C., Bhattacharya, A., Schmitt, C.A. and Lisec, J.
Analytical Chemistry 90
(12): 7253-7260.
19 June 2018
The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies.
Hoffmann, J., Hanß, S., Kraus, M., Schaller, J., Schäfer, C., Stahl, D., Anker, S.D., Anton, G., Bahls, T., Blankenberg, S., Blumentritt, A., Boldt, L.H., Cordes, S., Desch, S., Doehner, W., Dörr, M., Edelmann, F., Eitel, I., Endres, M., Engelhardt, S., Erdmann, J., Eulenburg, K., Falk, V., Felix, S.B., Frank, D., Franke, T., Frey, N., Friede, T., Geidel, L., Germans, L., Grabmaier, U., Halle, M., Hausleiter, J., Jakobi, V., Jebran, A.F., Jobs, A., Kääb, S., Karakas, M., Katus, H.A., Klatt, A., Knosalla, C., Krebser, J., Landmesser, U., Lee, M., Lehnert, K., Lesser, S., Leyh, K., Lorbeer, R., Mach-Kolb, S., Meder, B., Nagel, E., Nolte, C.H., Parwani, A.S., Petersmann, A., Puls, M., Rau, H., Reiser, M., Rienhoff, O., Scharfe, T., Schattschneider, M., Scheel, H., Schnabel, R.B., Schuster, A., Schmitt, B., Seidler, T., Seiffert, M., Stähli, B.E., Stas, A., Stocker, T.J., von Stülpnagel, L., Thiele, H., Wachter, R., Wakili, R., Weis, T., Weitmann, K., Wichmann, H.E., Wild, P., Zeller, T., Hoffmann, W., Zeisberg, E.M., Zimmermann, W.H., Krefting, D., Kühne, T., Peters, A., Hasenfuß, G., Massberg, S., Sommer, T., Dimmeler, S., Eschenhagen, T. and Nauck, M.
Clinical Research in Cardiology 112
(7): 923-941.
July 2023
Human alveolar progenitors generate dual lineage bronchioalveolar organoids.
Hoffmann, K., Obermayer, B., Hönzke, K., Fatykhova, D., Demir, Z., Löwa, A., Teixeira Alves, L.G., Wyler, E., Lopez-Rodriguez, E., Mieth, M., Baumgardt, M., Hoppe, J., Firsching, T.C., Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Gruber, A.D., Ochs, M., Landthaler, M., Beule, D., Suttorp, N., Hippenstiel, S., Hocke, A.C. and Kessler, M.
Communications Biology 5
(1): 875.
25 August 2022
FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease.
Hoffmann, S., Pentakota, S., Mund, A., Haahr, P., Coscia, F., Gallo, M., Mann, M., Taylor, N.M. and Mailand, N.
EMBO Reports 21
(10): e50662.
5 October 2020
Response evaluation in head and neck oncology: definition and prediction.
Hoffmann, T.K., Schuler, P.J., Laban, S., Grässlin, R., Beer, M., Beer, A.J., Friebe-Hoffmann, U., Bullinger, L., Möller, P. and Wiegel, T.
ORL 79
(1-2): 14-23.
February 2017
A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.
Hofgaard, P.O., Jodal, H.C., Bommert, K., Huard, B., Caers, J., Carlsen, H., Schwarzer, R., Schuenemann, N., Jundt, F., Lindeberg, M.M. and Bogen, B.
PLoS ONE 7
(12): e51892.
20 December 2012
The winged-helix transcription factor JUMU regulates development, nucleolus morphology and function, and chromatin organization of Drosophila melanogaster.
Hofmann, A., Bruenner, M., Schwendemann, A., Stroedicke, M., Karberg, S., Klebes, A., Saumweber, H. and Korge, G.
Chromosome Research 18
(3): 307-324.
April 2010
Screening for large rearrangements of the BRCA1 gene in German breast or ovarian cancer families using semi-quantitative multiplex PCR method.
Hofmann, W., Goergens, H., John, A., Horn, D., Huettner, C., Arnold, N., Scherneck, S. and Schackert, H.K.
Human Mutation 22
(1): 103-104.
1 July 2003
Identification of a recurrent BRCA1 mutation in German breast-cancer and/or ovarian-cancer families.
Hofmann, W., Jandrig, B., Classen, E., Nestle-Kraemling, C., Chang-Claude, J. and Scherneck, S.
Journal of Cancer Research and Clinical Oncology 127
(3): 200-202.
1 January 2001
Rap1 regulates the formation of E-cadherin-based cell-cell contacts.
Hogan, C., Serpente, N., Cogram, P., Hosking, C.R., Bialucha, C.U., Feller, S.M., Braga, V.M.M., Birchmeier, W. and Fujita, Y.
Molecular and Cellular Biology 24
(15): 6690-6700.
1 January 2004
Gastrointestinale Stromatumoren - Tumorentitaet und Therapie mit Imatinib.
Hohenberger, P., Reichardt, P., Stroszczynski, C., Schneider, U. and Hossfeld, D.K.
Deutsches Aerzteblatt 100
: 1334-1339.
1 January 2003
Isolated limb perfusion with rhTNF-alpha and melphalan for locally recurrent childhood synovial sarcoma of the limb.
Hohenberger, P. and Tunn, P.U.F.
Journal of Pediatric Hematology Oncology 25
: 905-909.
1 January 2003
Bildgebende Diagnostik im praeoperativen Staging beim Rektumkarzinom [Imaging modalities in the preoperative staging of rectal carcinoma].
Hohenberger, P., Huenerbein, M., Gebauer, B. and Stroszczynski, C.
Chirurg 75
(1): 3-12.
1 January 2004
Pentoxifyllin attenuates the systemic inflammatory response induced during isolated limb perfusion with recombinant human tumor necrosis factor-α and melphalan.
Hohenberger, P., Latz, E., Kettelhack, C., Rezaei, A.H., Schumann, R. and Schlag, P.M.
Annals of Surgical Oncology 10
(5): 562-568.
June 2003
MACC1-induced collective migration is promoted by proliferation rather than single cell biomechanics.
Hohmann, T., Hohmann, U., Dahlmann, M., Kobelt, D., Stein, U. and Dehghani, F.
Cancers 14
(12): 2857.
9 June 2022
MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma.
Hohmann, T., Hohmann, U., Kolbe, M.R., Dahlmann, M., Kobelt, D., Stein, U. and Dehghani, F.
Cell Communication and Signaling 18
(1): 85.
5 June 2020
B-cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.
Hojer, C., Frankenberger, S., Strobl, L.J., Feicht, S., Djermanovic, K., Jagdhuber, F., Hömig-Hölzel, C., Ferch, U., Ruland, J., Rajewsky, K. and Zimber-Strobl, U.
Cancer Research 74
(16): 4318-4328.
15 August 2014
Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor.
Holdhoff, M., Kreuzer, K.A., Appelt, C., Scholz, R., Na, I.K., Hildebrandt, B., Riess, H., Jordan, A., Schmidt, C.A., Van Etten, R.A., Doerken, B. and LeCoutre, P.
Blood Cells Molecules and Diseases 34
(2): 181-185.
1 March 2005
Wnt signaling in stem and cancer stem cells.
Holland, J.D., Klaus, A., Garratt, A.N. and Birchmeier, W.
Current Opinion in Cell Biology 25
(2): 254-264.
April 2013
Combined Wnt/β-catenin, met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome.
Holland, J.D., Györffy, B., Vogel, R., Eckert, K., Valenti, G., Fang, L., Lohneis, P., Elezkurtaj, S., Ziebold, U. and Birchmeier, W.
Cell Reports 5
(5): 1214-1227.
12 December 2013
Inflammation in children with chronic kidney disease linked to gut dysbiosis and metabolite imbalance.
Holle, J., Bartolomaeus, H., Löber, U., Behrens, F., Bartolomaeus, T.U.P., Anandakumar, H., Wimmer, M., Vu, D.L., Kuhring, M., Brüning, U., Maifeld, A., Geisberger, S., Kempa, S., Schumacher, F., Kleuser, B., Bufler, P., Querfeld, U., Kitschke, S., Engler, D., Kuhrt, L.D., Drechsel, O., Eckardt, K.U., Forslund, S., Thürmer, A., McParland, V., Kirwan, J., Wilck, N. and Mueller, D.
Journal of the American Society of Nephrology 33
(12): 2259-2275.
December 2022
RNA tomography for spatially resolved transcriptomics (Tomo-seq).
Holler, K. and Junker, J.P.
Methods in Molecular Biology 1920
: 129-141.
2019
Spatio-temporal mRNA tracking in the early zebrafish embryo.
Holler, K., Neuschulz, A., Drewe-Boß, P., Mintcheva, J., Spanjaard, B., Arsiè, R., Ohler, U., Landthaler, M. and Junker, J.P.
Nature Communications 12
: 3358.
7 June 2021
Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity.
Holst, P.J., Rosenkilde, M.M., Manfra, D., Chen, S.C., Wiekowski, M.T., Holst, B., Cifire, F., Lipp, M., Schwartz, T.W. and Lira, S.A.
Journal of Clinical Investigation 108
(12): 1789-1796.
December 2001
Strategies for identifying RNA splicing regulatory motifs and predicting alternative splicing events.
Holste, D. and Ohler, U.
PLoS Computational Biology 4
(1): e21.
25 January 2008
Efficient non-viral gene delivery into human hematopoietic stem cells by minicircle Sleeping Beauty transposon vectors.
Holstein, M., Mesa-Nuñez, C., Miskey, C., Almarza, E., Poletti, V., Schmeer, M., Grueso, E., Ordóñez Flores, J.C., Kobelt, D., Walther, W., Aneja, M.K., Geiger, J,, Bonig, H.B., Izsvák, Z., Schleef, M., Rudolph, C., Mavilio, F., Bueren, J.A., Guenechea, G. and Ivics, Z.
Molecular Therapy 26
(4): 1137-1153.
4 April 2018
Developmental stage-specific shift in responsiveness to chemokines during human B-cell development.
Honczarenko, M., Glodek, A.M., Swierkowski, M., Na, I.K. and Silberstein, L.E.
Experimental Hematology 34
(8): 1093-1100.
August 2006
Authentication of primary murine cell lines by a microfluidics-based lab-on-chip system.
Hong, Y., Singh, N., Bamopoulos, S., Gjerga, E., Schmalbrock, L.K., Balabanian, K., Schick, M., Keller, U. and Wirth, M.
Biomedicines 8
(12): 590.
9 December 2020
Lebensqualitaet nach Rektumchirurgie [Quality of life after rectal surgery].
Hoppe de Mamani, S. and Schlag, P.M.
Chirurg 75
(1): 26-31.
January 2004
Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.
Horatscheck, A., Wagner, S., Ortwein, J., Kim, B.G., Lisurek, M., Beligny, S., Schuetz, A. and Rademann, J.
Angewandte Chemie International Edition 51
(37): 9441-9447.
10 September 2012
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
Horkova, V., Drobek, A., Paprckova, D., Niederlova, V., Prasai, A., Uleri, V., Glatzova, D., Kraller, M., Cesnekova, M., Janusova, S., Salyova, E., Tsyklauri, O., Kadlecek, T.A., Krizova, K., Platzer, R., Schober, K., Busch, D.H., Weiss, A., Huppa, J.B. and Stepanek, O.
Nature Immunology 24
(1): 174-185.
January 2023
A computational map of the human-SARS-CoV-2 protein-RNA interactome predicted at single-nucleotide resolution.
Horlacher, M., Oleshko, S., Hu, Y., Ghanbari, M., Cantini, G., Schinke, P., Vergara, E.E., Bittner, F., Mueller, N.S, Ohler, U., Moyon, L. and Marsico, A.
NAR Genomics and Bioinformatics 5
(1): lqad010.
March 2023
Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4(+) T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease.
Horn, V., Cancino, C.A., Steinheuer, L.M., Obermayer, B., Fritz, K., Nguyen, A.L., Juhran, K.S., Plattner, C., Bösel, D., Oldenburg, L., Burns, M., Schulz, A.R., Saliutina, M., Mantzivi, E., Lissner, D., Conrad, T., Mashreghi, M.F., Zundler, S., Sonnenberg, E., Schumann, M., Haag, L.M., Beule, D., Flatz, L., Trjanoski, Z., D'Haens, G., Weidinger, C., Mei, H.E., Siegmund, B., Thurley, K. and Hegazy, A.N.
Gastroenterology
28 September 2024
(In Press)
Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C., Hanna, J., Hirsch, C., Volkwein, C., Schütz, A., Heinemann, U., Sommer, T. and Jarosch, E.
Molecular Cell 36
(5): 782-793.
11 December 2009
Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial.
Horwitz, S., O'Connor, O.A., Pro, B., Illidge, T., Fanale, M., Advani, R., Bartlett, N.L., Christensen, J.H., Morschhauser, F., Domingo-Domenech, E., Rossi, G., Kim, W.S., Feldman, T., Lennard, A., Belada, D., Illés, A., Tobinai, K., Tsukasaki, K., Yeh, S.P., Shustov, A., Hüttmann, A., Savage, K.J., Yuen, S., Iyer, S., Zinzani, P.L., Hua, Z., Little, M., Rao, S., Woolery, J., Manley, T. and Trümper, L.
Lancet 393
(10168): 229-240.
19 January 2019
Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D., Schön, C., Loddenkemper, C., Lohneis, P., Kühl, A.A., Sommermann, T., Blankenstein, T. and Willimsky, G.
Blood 132
(9): 924-934.
30 August 2018
The transcriptional repressor Glis2 is a novel binding partner for p120 catenin.
Hosking, C.R., Ulloa, F., Hogan, C., Ferber, E., Figueroa, A., Gevaert, K., Birchmeier, W., Briscoe, J. and Fujita, Y.
Molecular Biology of the Cell 18
(5): 1918-1927.
1 May 2007
Inhibiting the inhibitors: retro-inverso Smac peptides.
Hossbach, J., Michalsky, E., Henklein, P., Jaeger, M., Daniel, P.T. and Preissner, R.
Peptides 30
(12): 2374-2379.
December 2009
A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain.
Hossini, A.M., Geilen, C.C., Fecker, L.F., Daniel, P.T. and Eberle, J.
Oncogene 25
: 2160-2169.
6 April 2006
Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
Houwaart, Torsten, Belhaj, S., Tawalbeh, E., Nagels, D., Fröhlich, Y., Finzer, P., Ciruela, P., Sabrià, A., Herrero, M., Andrés, C., Antón, A., Benmoumene, A., Asskali, D., Haidar, H., von Dahlen, J., Nicolai, J., Stiller, M., Blum, J., Lange, C., Adelmann, C., Schroer, B., Osmers, U., Grice, C., Kirfel, P.P., Jomaa, H., Strelow, D., Hülse, L., Pigulla, M., Kreuzer, P., Tyshaieva, A., Weber, J., Wienemann, T., Kohns Vasconcelos, M., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Scholz, C.J., Jazmati, N., Göbels, K., Zotz, R., Pfeffer, K., Timm, J., Ehlkes, L., Walker, A. and Dilthey, A.T.
Eurosurveillance 27
(43): 2101089.
27 October 2022
A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: results from the CONKO-005 trial.
Hoyer, K., Hablesreiter, R., Inoue, Y., Yoshida, K., Briest, F., Christen, F., Kakiuchi, N., Yoshizato, T., Shiozawa, Y., Shiraishi, Y., Striefler, J.K., Bischoff, S., Lohneis, P., Putter, H., Blau, O., Keilholz, U., Bullinger, L., Pelzer, U., Hummel, M., Riess, H., Ogawa, S., Sinn, M. and Damm, F.
EBioMedicine 66
: 103327.
April 2021
Protocol for fast scRNA-seq raw data processing using scKB and non-arbitrary quality control with COPILOT.
Hsu, C.W., Shahan, R., Nolan, T.M., Benfey, P.N. and Ohler, U.
STAR Protocols 3
(4): 101729.
16 December 2022
Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis.
Hsu, P.Y., Calviello, L., Wu, H.Y.L., Li, F.W., Rothfels, C.J., Ohler, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 113
(45): E7126-E7135.
8 November 2016
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F., a Dzaye, O.D., Hahn, A., Yu, Y., Scavetta, R.J., Dittmar, G., Kaczmarek, A.K., Dunning, K.R., Ricciardelli, C., Rinnenthal, J.L., Heppner, F.L., Lehnardt, S., Synowitz, M., Wolf, S.A. and Kettenmann, H.
Neuro-Oncology 17
(2): 200-210.
February 2015
Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway.
Hu, H., Jiang, C., Schuster, T., Li, G.X., Daniel, P.T. and Lue, J.
Molecular Cancer Therapeutics 5
: 1873-1882.
July 2006
TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activation.
Hu, W.H., Mo, X.M., Walters, W.M., Brambilla, R. and Bethea, J.R.
Journal of Biological Chemistry 279
(34): 35975-35983.
1 January 2004
Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.
Hu, Y.C., Nicholls, P.K., Soh, Y.Q.S., Daniele, J.R., Junker, J.P., van Oudenaarden, A. and Page, D.C.
PLoS Genetics 11
(3): e1005019.
4 March 2015
Origin and function of activated fibroblast states during zebrafish heart regeneration.
Hu, B., Lelek, S., Spanjaard, B., El-Sammak, H., Simões, M.G., Mintcheva, J., Aliee, H., Schäfer, R., Meyer, A.M., Theis, F., Stainier, D.Y.R., Panáková, D. and Junker, J.P.
Nature Genetics 54
(8): 1227-1237.
August 2022
Genetics of intellectual disability in consanguineous families.
Hu, H., Kahrizi, K., Musante, L., Fattahi, Z., Herwig, R., Hosseini, M., Oppitz, C., Abedini, S.S., Suckow, V., Larti, F., Beheshtian, M., Lipkowitz, B., Akhtarkhavari, T., Mehvari, S., Otto, S., Mohseni, M., Arzhangi, S., Jamali, P., Mojahedi, F., Taghdiri, M., Papari, E., Soltani Banavandi, M.J., Akbari, S., Tonekaboni, S.H., Dehghani, H., Ebrahimpour, M.R., Bader, I., Davarnia, B., Cohen, M., Khodaei, H., Albrecht, B., Azimi, S., Zirn, B., Bastami, M., Wieczorek, D., Bahrami, G., Keleman, K., Vahid, L.N., Tzschach, A., Gärtner, J., Gillessen-Kaesbach, G., Varaghchi, J.R., Timmermann, B., Pourfatemi, F., Jankhah, A., Chen, W., Nikuei, P., Kalscheuer, V.M., Oladnabi, M., Wienker, T.F., Ropers, H.H. and Najmabadi, H.
Molecular Psychiatry 24
(7): 1027-1039.
July 2019
FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells.
Hu, J.L., Liang, H., Zhang, H., Yang, M.Z., Sun, W., Zhang, P., Luo, L., Feng, J.X., Bai, H., Liu, F., Zhang, T., Yang, J.Y., Gao, Q., Long, Y., Ma, X.Y., Chen, Y., Zhong, Q., Yu, B., Liao, S., Wang, Y., Zhao, Y., Zeng, M.S., Cao, N., Wang, J., Chen, W., Yang, H.T. and Gao, S.
Nucleic Acids Research 48
(5): 2733-2748.
18 March 2020
Calorie restriction enhanced glycogen metabolism to compensate for lipid insufficiency.
Hu, L., Xia, X., Zong, Y., Gu, Y., Wei, L. and Yin, J.
Molecular Nutrition & Food Research 66
(20): 2200182.
October 2022
Phylogenetic simulation of promoter evolution: estimation and modeling of binding site turnover events and assessment of their impact on alignment tools.
Huang, W., Nevins, J.R. and Ohler, U.
Genome Biology 8
(10): R225.
24 October 2007
Optimized mixed Markov models for motif identification.
Huang, W., Umbach, D.M., Ohler, U. and Li, L.
BMC Bioinformatics 7
: 279.
2 June 2006
Delivery of therapeutics targeting the mRNA-binding protein HuR using 3DNA nanocarriers suppresses ovarian tumor growth.
Huang, Y.H., Peng, W., Furuuchi, N., Gerhart, J., Rhodes, K., Mukherjee, N., Jimbo, M., Gonye, G.E., Brody, J.R., Getts, R.C. and Sawicki, J.A.
Cancer Research 76
(6): 1549-1559.
15 March 2016
Chemodetection and destruction of host urea allows Helicobacter pylori to locate the epithelium.
Huang, J.Y., Sweeney Goers, E., Sigal, M., Zhang, H.C., Remington, S.J., Cantrell, M.A., Kuo, C.J., Guillemin, K. and Amieva, M.R.
Cell Host & Microbe 18
(2): 147-156.
12 August 2015
Comparison of proteomic and genomic analyses of the human breast cancer cell line T47D and the antiestrogen-resistant derivative T47D-r.
Huber, M., Bahr, I., Kraetzschmar, J.R., Becker, A., Mueller, E.C., Donner, P., Pohlenz, H.D., Schneider, M.R. and Sommer, A.
Molecular and Cellular Proteomics 3
(1): 43-55.
January 2004
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
Huelsken, J., Birchmeier, W. and Behrens, J.
Journal of Cell Biology 127
(6 Pt. 2): 2061-2069.
December 1994
Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J., Vogel, R., Brinkmann, V., Erdmann, B., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 148
(3): 567-578.
7 February 2000
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G. and Birchmeier, W.
Cell 105
(4): 533-545.
18 May 2001
Local and central evaluation of HER2 positivity and clinical outcome in advanced gastric and gastroesophageal cancer: results from the AGMT GASTRIC-5 Registry.
Huemer, F., Weiss, L., Regitnig, P., Winder, T., Hartmann, B., Thaler, J., Piringer, G., Schmitt, C.A., Eisterer, W., Gänzer, H., Wüstner, Al., Andel, J., Jagdt, B., Ulmer, H., Greil, R. and Wöll, E.
Journal of Clinical Medicine 9
(4): 935.
29 March 2020
The role of staging laparoscopy for multimodal therapy of gastrointestinal cancer.
Huenerbein, M., Rau, B., Hohenberger, P. and Schlag, P.M.
Surgical Endoscopy 12
(7): 921-925.
July 1998
EUS-guided fine needle biopsy: minimally invasive access to metastatic or recurrent cancer.
Huenerbein, M., Totkas, S., Balanou, P., Handke, T. and Schlag, P.M.
European Journal of Ultrasound 10
(2-3): 151-157.
November 1999
Transkutane Sonographie.
Huenerbein, M., Chopra, S.S. and Schlag, P.M.
Chirurg 78
(5): 407-412.
May 2007
Traumareduktion durch minimal invasive Chirurgie : Gesicherte Daten und neue Strategien [Reducing trauma with minimally invasive surgery. Evidence and new strategies].
Huenerbein, M., Gretschel, S., Rau, B. and Schlag, P.M.
Chirurg 74
(4): 282-289.
April 2003
Impact of miniprobe ultrasonography on planning of minimally invasive surgery for gastric and colonic tumors.
Huenerbein, M., Handke, T., Ulmer, C. and Schlag, P.M.
Surgical Endoscopy 18
(4): 601-605.
April 2004
Resection of soft tissue sarcoma of the lower limb after evaluation of vascular invasion with intraoperative intravascular ultrasonography.
Huenerbein, M., Hohenberger, P., Stroszczynski, C., Bartelt, N., Schlag, P.M. and Tunn, P.U.
British Journal of Surgery 94
: 168-173.
February 2007
Palliation of malignant rectal obstruction with self-expanding metal stents.
Huenerbein, M., Krause, M., Moesta, K.T., Rau, B. and Schlag, P.M.
Surgery 137
: 42-47.
1 January 2005
Ductoscopy and intraductal vacuum assisted biopsy in women with pathologic nipple discharge.
Huenerbein, M., Raubach, M., Gebauer, B., Schneider, W. and Schlag, P.M.
Breast Cancer Research and Treatment 99
(3): 301-307.
October 2006
Intraoperative ductoscopy in women undergoing surgery for breast cancer.
Huenerbein, M., Raubach, M., Gebauer, B., Schneider, W. and Schlag, P.M.
Surgery 139
: 833-838.
June 2006
[R1 resection in the region of the lower gastrointestinal tract: relevance and therapeutic consequences].
Huenerbein, M. and Schlag, P.M.
Chirurg 78
(9): 810-817.
September 2007
Treatment of thoracic anastomotic leaks after esophagectomy with self-expanding plastic stents.
Huenerbein, M., Stroszczynski, C., Moesta, K.T. and Schlag, P.M.
Annals of Surgery 240
: 801-807.
1 January 2004
Prospective comparison of transcutaneous 3-dimensional US cholangiography, magnetic resonance cholangiography, and direct cholangiography in the evaluation of malignant biliary obstruction.
Huenerbein, M., Stroszczynski, C., Ulmer, C., Handke, T., Felix, R. and Schlag, P.M.
Gastrointestinal Endoscopy 58
(6): 853-858.
December 2003
Potential applications of microendoscopy in surgery.
Huenerbein, M., Totkas, S., Khodadadyan, C. and Schlag, P.M.
Surgical Technology International 9
: 105-110.
2000
Endosonography of upper gastrointestinal tract cancer on demand using miniprobes or endoscopic ultrasound.
Huenerbein, M., Ulmer, C., Handke, T. and Schlag, P.M.
Surgical Endoscopy 17
(4): 615-619.
April 2003
Women in the European Virus Bioinformatics Center.
Hufsky, F., Abecasis, A., Agudelo-Romero, P., Bletsa, M., Brown, K., Claus, C., Deinhardt-Emmer, S., Deng, L., Friedel, C.C., Gismondi, M.I., Kostaki, E.G., Kühnert, D., Kulkarni-Kale, U., Metzner, K.J., Meyer, I.M., Miozzi, L., Nishimura, L., Paraskevopoulou, S., Pérez-Cataluña, A., Rahlff, J., Thomson, E., Tumescheit, C., van der Hoek, L., Van Espen, L., Vandamme, A.M., Zaheri, M., Zuckerman, N. and Marz, M.
Viruses 14
(7): 1522.
12 July 2022
The International Virus Bioinformatics Meeting 2020.
Hufsky, F., Beerenwinkel, N., Meyer, I.M., Roux, S., Cook, G.M., Kinsella, C.M., Lamkiewicz, K., Marquet, M., Nieuwenhuijse, D.F., Olendraite, I., Paraskevopoulou, S., Young, F., Dijkman, R., Ibrahim, B., Kelly, J., Le Mercier, P., Marz, M., Ramette, A. and Thiel, V.
Viruses 12
(12): 1398.
6 December 2020
Coordinated inheritance of extrachromosomal DNAs in cancer cells.
Hung, K.L., Jones, M.G., Wong, I.T.L., Curtis, E.J., Lange, J.T., He, B.J., Luebeck, J., Schmargon, R., Scanu, E., Brückner, L., Yan, X., Li, R., Gnanasekar, A., Chamorro González, R., Belk, J.A., Liu, Z., Melillo, B., Bafna, V., Dörr, J.R., Werner, B., Huang, W., Cravatt, B.F., Henssen, A.G., Mischel, P.S and Chang, H.Y.
Nature 635
(8037): 201-209.
7 November 2024
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
Hung, K.L., Luebeck, J., Dehkordi, S.R., Colón, C.I., Li, R., Wong, I.T.L., Coruh, C., Dharanipragada, P., Lomeli, S.H., Weiser, N.E., Moriceau, G., Zhang, X., Bailey, C., Houlahan, K.E., Yang, W., González, R.C., Swanton, C., Curtis, C., Jamal-Hanjani, M., Henssen, A.G., Law, J.A., Greenleaf, W.J., Lo, R.S., Mischel, P.S., Bafna, V. and Chang, H.Y.
Nature Genetics 54
(11): 1746–1754.
November 2022
ecDNA hubs drive cooperative intermolecular oncogene expression.
Hung, K.L., Yost, K.E., Xie, L., Shi, Q., Helmsauer, K., Luebeck, J., Schöpflin, R., Lange, J.T., Chamorro González, R., Weiser, N.E., Chen, C., Valieva, M.E., Wong, I.T.L., Wu, S., Dehkordi, S.R., Duffy, C.V., Kraft, K., Tang, J., Belk, J.A., Rose, J.C., Corces, M.R., Granja, J.M., Li, R., Rajkumar, U., Friedlein, J., Bagchi, A., Satpathy, A.T., Tjian, R., Mundlos, S., Bafna, V., Henssen, A.G., Mischel, P.S., Liu, Z. and Chang, H.Y.
Nature 600
(7890): 731-736.
23 December 2021
Complete male-to-female sex reversal in XY mice lacking the miR-17~92 cluster.
Hurtado, A., Mota-Gómez, I., Lao, M., Real, F.M., Jedamzick, J., Burgos, M., Lupiáñez, D.G., Jiménez, R. and Barrionuevo, F.J.
Nature Communications 15
(1): 3809.
7 May 2024
Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy.
Hähnel, P.S., Enders, B., Sasca, D., Roos, W.P., Kaina, B., Bullinger, L., Theobald, M. and Kindler, T.
Blood 123
(15): 2355-2366.
10 April 2014
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke, K., Obermayer, B., Mache, C., Fathykova, D., Kessler, M., Dökel, S., Wyler, E., Baumgardt, M., Löwa, A., Hoffmann, K., Graff, P., Schulze, J., Mieth, M., Hellwig, K., Demir, Z., Biere, B., Brunotte, L., Mecate-Zambrano, A., Bushe, J., Dohmen, M., Hinze, C., Elezkurtaj, S., Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Schmidt-Ott, K.M., Busch, J., Klauschen, F., Horst, D., Radbruch, H., Radke, J., Heppner, F., Corman, V.M., Niemeyer, D., Müller, M.A., Goffinet, C., Mothes, R., Pascual-Reguant, A., Hauser, A.E., Beule, D., Landthaler, M., Ludwig, S., Suttorp, N., Witzenrath, M., Gruber, A.D., Drosten, C., Sander, L.E., Wolff, T., Hippenstiel, S. and Hocke, A.C.
European Respiratory Journal 60
(6): 2102725.
1 December 2022
Inhibition of interleukin-6 synthesis in an animal model of septic shock by anti-C5a monoclonal antibodies.
Höpken, U., Mohr, M., Strueber, A., Montz, H., Burchardi, H., Götze, O. and Oppermann, M.
European Journal of Immunology 26
(5): 1103-1109.
May 1996
Distinct and overlapping roles of CXCR5 and CCR7 in B-1 cell homing and early immunity against bacterial pathogens.
Höpken, U.E., Achtman, A.H., Krueger, K. and Lipp, M.
Journal of Leukocyte Biology 76
(3): 709-718.
September 2004
The chemokine receptor CCR7 controls lymph node-dependent cytotoxic T cell priming in alloimmune responses.
Höpken, U.E., Droese, J., Li, J.P., Joergensen, J., Breitfeld, D., Zerwes, H.G. and Lipp, M.
European Journal of Immunology 34
(2): 461-470.
1 January 2004
Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs.
Höpken, U.E., Foss, H.D., Meyer, D., Hinz, M., Leder, K., Stein, H. and Lipp, M.
Blood 99
(4): 1109-1116.
1 January 2002
The ratio between dendritic cells and T cells determines the outcome of their encounter: Proliferation versus deletion.
Höpken, U.E., Lehmann, I., Droese, J., Lipp, M., Schueler, T. and Rehm, A.
European Journal of Immunology 35
(10): 2851-2863.
23 September 2005
Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor.
Höpken, U.E., Lu, B., Gerard, N.P. and Gerard, C.
Journal of Experimental Medicine 186
(5): 749-756.
29 August 1997
The C5a chemoattractant receptor mediates mucosal defence to infection.
Höpken, U.E., Lu, B., Gerard, N.P. and Gerard, C.
Nature 383
(6595): 86-89.
5 September 1996
CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
Höpken, U.E., Wengner, A.M., Loddenkemper, C., Stein, H., Heimesaat, M.M., Rehm, A. and Lipp, M.
Blood 109
(3): 886-895.
1 February 2007
CCR7 regulates lymphocyte egress and recirculation through body cavities.
Höpken, U.E., Winter, S., Achtman, A.H., Krueger, K. and Lipp, M.
Journal of Leukocyte Biology 87
(4): 671-682.
April 2010
Risk factors and characteristics influencing humoral response to COVID-19 vaccination in patients after allogeneic stem cell transplantation.
Hütter-Krönke, M.L., Neagoie, A., Blau, I.W., Wais, V., Vuong, L., Gantner, A., Ahn, J., Penack, O., Schnell, J., Nogai, K.A., Eberspächer, B., Saadati, M., Benner, A., Bullinger, L., Döhner, H., Bunjes, D. and Sala, E.
Frontiers in Immunology 14
: 1174289.
3 May 2023
Tumor rejection by disturbing tumor stroma cell interactions.
Ibe, S., Qin, Z.H., Schueler, T., Preiss, S. and Blankenstein, T.
Journal of Experimental Medicine 194
(11): 1549-1559.
3 December 2001
JAMM: a peak finder for joint analysis of NGS replicates.
Ibrahim, M.M., Lacadie, S.A. and Ohler, U.
Bioinformatics 31
(1): 48-55.
1 January 2015
Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M., Karabacak, A., Glahs, A., Kolundzic, E., Hirsekorn, A., Carda, A., Tursun, B., Zinzen, R.P., Lacadie, S.A. and Ohler, U.
Nature Communications 9
(1): 4472.
26 October 2018
Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Iftekhar, A., Berger, H., Bouznad, N., Heuberger, J., Boccellato, F., Dobrindt, U., Hermeking, H., Sigal, M. and Meyer, T.F.
Nature Communications 12
(1): 1003.
12 February 2021
Defence and adaptation mechanisms of the intestinal epithelium upon infection.
Iftekhar, A. and Sigal, M.
International Journal of Medical Microbiology 311
(3): 151486.
April 2021
Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow, J., Gross, S., Busack, L., Flörcken, A., Jesse, J., Schwarz, M., Neuendorff, N.R., von Brünneck, A.C., Anagnostopoulos, I., Türkmen, S., Blau, I.W., Burmeister, T., Horst, D., Bullinger, L. and Westermann, J.
Haematologica 107
(8): 1773-1785.
August 2022
Clinical outcome of older adults with acute myeloid leukemia: an analysis of a large tertiary referral center over two decades.
Ihlow, J., Gross, S., Neuendorff, N.R., Busack, L., Herneth, A., Singh, A., Schwarz, M., Flörcken, A., Anagnostopoulos, I., Türkmen, S., Burmeister, T., Blau, I.W., Bullinger, L. and Westermann, J.
Journal of Geriatric Oncology 12
(4): 540-549.
May 2021
B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased.
Ihlow, J., Michaelis, E., Greuel, S., Heynol, V., Lehmann, A., Radbruch, H., Meinhardt, J., Miller, F., Herbst, H., Corman, V.M., Westermann, J., Bullinger, L., Horst, D., von Brünneck, A.C. and Elezkurtaj, S.
International Journal of Infectious Diseases 103
: 628-635.
February 2021
MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer.
Ilm, K., Fuchs, S., Mudduluru, G. and Stein, U.
Oncotarget 7
(33): 53443-53458.
16 August 2016
High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.
Ilm, K., Kemmner, W., Osterland, M., Burock, S., Koch, G., Herrmann, P., Schlag, P.M. and Stein, U.
Molecular Cancer 14
(1): 38.
14 February 2015
Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during mitosis.
Imami, K., Milek, M., Bogdanow, B., Yasuda, T., Kastelic, N., Zauber, H., Ishihama, Y., Landthaler, M. and Selbach, M.
Molecular Cell 72
(1): 84-98.
4 October 2018
Monitoring mitochondrial translation by pulse SILAC.
Imami, K., Selbach, M. and Ishihama, Y.
Journal of Biological Chemistry 299
(2): 102865.
February 2023
MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari, F., Dahlmann, M., Sporbert, A., Ciolli Mattioli, C., Mari, T., Scholz, F., Timm, L., Twamley, S., Migotti, R., Walther, W., Dittmar, G., Rehm, A. and Stein, U.
Cellular and Molecular Life Sciences 78
(7): 3525-3542.
April 2021
Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors.
Immisch, L., Papafotiou, G., Gallarín Delgado, N., Scheuplein, V., Paschen, A., Blankenstein, T. and Willimsky, G.
Frontiers in Immunology 14
: 1119498.
16 February 2023
H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2(+) patients with diffuse midline glioma.
Immisch, L., Papafotiou, G., Popp, O., Mertins, P., Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 10
(10): e005535.
27 October 2022
SIRT1 regulates macrophage self-renewal.
Imperatore, F., Maurizio, J., Vargas Aguilar, S., Busch, C.J., Favret, J., Kowenz-Leutz, E., Cathou, W., Gentek, R., Perrin, P., Leutz, A., Berruyer, C. and Sieweke, M.H.
EMBO Journal 36
(16): 2353-2372.
15 August 2017
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G., Rybak-Wolf, A., Lisowski, P., Pentimalli, T.M., Jüttner, R., Glažar, P., Uppal, K., Bottani, E., Brunetti, D., Secker, C., Zink, A., Meierhofer, D., Henke, M.T., Dey, M., Ciptasari, U., Mlody, B., Hahn, T., Berruezo-Llacuna, M., Karaiskos, N., Di Virgilio, M., Mayr, J.A., Wortmann, S.B., Priller, J., Gotthardt, M., Jones, D.P., Mayatepek, E., Stenzel, W., Diecke, S., Kühn, R., Wanker, E.E., Rajewsky, N., Schuelke, M. and Prigione, A.
Nature Communications 12
(1): 1929.
26 March 2021
Variable outcomes of hepatitis E infections in patients with hemato-oncologic diseases.
Ingwersen, V., Hofmann, J., Muche, M., Le Coutre, P., Schneider, T., Leng, C., Burmeister, T., Maschmeyer, G., Keller, U. and Schwartz, S.
Oncology Research and Treatment 46
(7-8): 296-302.
August 2023
Structure of tetrameric forms of the serotonin-gated 5-HT3(A) receptor ion channel.
Introini, B., Cui, W., Chu, X., Zhang, Y., Alves, A.C., Eckhardt-Strelau, L., Golusik, S., Tol, M., Vogel, H., Yuan, S. and Kudryashev, M.
EMBO Journal
4 September 2024
Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: a comprehensive examination of the potential carriers for semiochemicals.
Iovinella, I., McAfee, A., Mastrobuoni, G., Kempa, S., Foster, L.J., Pelosi, P. and Dani, F.R.
Journal of Proteomics 181
: 131-141.
15 June 2018
Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway.
Irigoyen, J.P., Besser, D. and Nagamine, Y.
Journal of Biological Chemistry 272
(3): 1904-1909.
17 January 1997
Pantoea stewartii WceF is a glycan biofilm modifying enzyme with a bacteriophage tailspike-like fold.
Irmscher, T., Roske, Y., Gayk, I., Dunsing, V., Chiantia, S., Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 296
: 100286.
2021
Plakoglobin is essential for myocardial compliance but dispensable for myofibril insertion into adherens junctions.
Isac, C.M., Ruiz, P., Pfitzmaier, B., Haase, H., Birchmeier, W. and Morano, I.
Journal of Cellular Biochemistry 72
(1): 8-15.
1 January 1999
Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC.
Ishikawa, S., Sato, T., Abe, M., Nagai, S., Onai, N., Yoneyama, H., Zhang, Y.Y., Suzuki, T., Hashimoto, S., Shirai, T., Lipp, M. and Matsushima, K.
Journal of Experimental Medicine 193
(12): 1393-1402.
18 June 2001
In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy.
Ishimaru, N., Nitta, T., Arakaki, R., Yamada, A., Lipp, M., Takahama, Y. and Hayashi, Y.
PLoS ONE 5
(1): e8588.
5 January 2010
CCR7 with S1P(1) signaling through AP-1 for migration of Foxp3(+) regulatory T-cells controls autoimmune exocrinopathy.
Ishimaru, N., Yamada, A., Nitta, T., Arakaki, R., Lipp, M., Takahama, Y. and Hayashi, Y.
American Journal of Pathology 180
(1): 199-208.
January 2012
Targeted Sleeping Beauty transposition in human cells.
Ivics, Z., Katzer, A., Stuewe, E.E., Fiedler, D., Knespel, S. and Izsvak, Z.
Molecular Therapy 15
(6): 1137-1144.
June 2007
Impact of the first COVID-19 lockdown in Germany on the rate of acute infections during intensive chemotherapy for Hodgkin lymphoma.
Jacob, A.S., Kaul, H., Fuchs, M., Gillessen, S., Kreissl, S., Pluetschow, A., Momotow, J., Schaub, V., Huettmann, A., Haenel, M., Zimmermann, A., Dierlamm, J., Meissner, J., Mathas, S., Martin, S., Engert, A., Hallek, M., Borchmann, P. and Lehmann, C.
Infection 50
(4): 925-932.
August 2022
Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Jacquelin, S., Straube, J., Cooper, L., Vu, T., Song, A., Bywater, M., Baxter, E., Heidecker, M., Wackrow, B., Porter, A., Ling, V., Green, J., Austin, R., Kazakoff, S., Waddell, N., Hesson, L.B., Pimanda, J.E., Stegelmann, F., Bullinger, L., Döhner, K., Rampal, R.K., Heckl, D., Hill, G.R. and Lane, S.W.
Blood 132
(26): 2707-2721.
27 December 2018
DNA microarray and miRNA analyses reinforce the classification of follicular thyroid tumors.
Jacques, C., Guillotin, D., Fontaine, J.F., Franc, B., Mirebeau-Prunier, D., Fleury, A., Malthiery, Y. and Savagner, F.
Journal of Clinical Endocrinology and Metabolism 98
(5): E981-E989.
May 2013
Automated annotation and evaluation of in-source mass spectra in GC/atmospheric pressure chemical ionization-MS-based metabolomics.
Jaeger, C., Hoffmann, F., Schmitt, C.A. and Lisec, J.
Analytical Chemistry 88
(19): 9386-9390.
4 October 2016
Compound annotation in liquid chromatography/high-resolution mass spectrometry based metabolomics: robust adduct ion determination as a prerequisite to structure prediction in electrospray ionization mass spectra.
Jaeger, C., Méret, M., Schmitt, C.A. and Lisec, J.
Rapid Communications in Mass Spectrometry 31
(15): 1261-1266.
15 August 2017
Yos9p assists in the degradation of certain non-glycosylated proteins from the endoplasmic reticulum.
Jaenicke, L.A., Brendebach, H., Selbach, M. and Hirsch, C.
Molecular Biology of the Cell 22
(16): 2937-2945.
August 2011
Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling.
Jaervinen, E., Salazar-Ciudad, I., Birchmeier, W., Taketo, M.M., Jernvall, J. and Thesleff, I.
Proceedings of the National Academy of Sciences of the United States of America 103
(49): 18627-18632.
5 December 2006
Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.
Jahn, E., Saadati, M., Fenaux, P., Gobbi, M., Roboz, G.J., Bullinger, L., Lutsik, P., Riedel, A., Plass, C., Jahn, N., Walter, C., Holzmann, K., Hao, Y., Naim, S., Schreck, N., Krzykalla, J., Benner, A., Keer, H.N., Azab, M., Döhner, K. and Döhner, H.
Leukemia 37
(11): 2187-2196.
November 2023
Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.
Jahn, N., Jahn, E., Saadati, M., Bullinger, L., Larson, R.A., Ottone, T., Amadori, S., Prior, T.W., Brandwein, J.M., Appelbaum, F.R., Medeiros, B.C., Tallman, M.S., Ehninger, G., Heuser, M., Ganser, A., Pallaud, C., Gathmann, I., Krzykalla, J., Benner, A., Bloomfield, C.D., Thiede, C., Stone, R.M., Döhner, H. and Döhner, K.
Leukemia 36
(9): 2218-2227.
September 2022
Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.
Jahn, N., Terzer, T., Sträng, E., Dolnik, A., Cocciardi, S., Panina, E., Corbacioglu, A., Herzig, J., Weber, D., Schrade, A., Götze, K., Schröder, T., Lübbert, M., Wellnitz, D., Koller, E., Schlenk, R.F., Gaidzik, V.I., Paschka, P., Rücker, F.G., Heuser, M., Thol, F., Ganser, A., Benner, A., Döhner, H., Bullinger, L. and Döhner, K.
Blood Advances 4
(24): 6342-6352.
22 December 2020
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.
Jakobsen, J.S., Laursen, L.G., Schuster, M.B., Pundhir, S., Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mönch, K., Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. and Porse, B.T.
Science Advances 5
(7): eaaw4304.
July 2019
Tracking the evolution of non-small-cell lung cancer.
Jamal-Hanjani, M., Wilson, G.A., McGranahan, N., Birkbak, N.J., Watkins, T.B.K., Veeriah, S., Shafi, S., Johnson, D.H., Mitter, R., Rosenthal, R., Salm, M., Horswell, S., Escudero, M., Matthews, N., Rowan, A., Chambers, T., Moore, D.A., Turajlic, S., Xu, H., Lee, S.-M., Forster, M.D., Ahmad, T., Hiley, C.T., Abbosh, C., Falzon, M., Borg, E., Marafioti, T., Lawrence, D., Hayward, M., Kolvekar, S., Panagiotopoulos, N., Janes, S.M., Thakrar, R., Ahmed, A., Blackhall, F., Summers, Y., Shah, R., Joseph, L., Quinn, A.M., Crosbie, P.A., Naidu, B., Middleton, G., Langman, G., Trotter, S., Nicolson, M., Remmen, H., Kerr, K., Chetty, M., Gomersall, L., Fennell, D.A., Nakas, A., Rathinam, S., Anand, G., Khan, S., Russell, P., Ezhil, V., Ismail, B., Irvin-Sellers, M., Prakash, V., Lester, J.F., Kornaszewska, M., Attanoos, R., Adams, H., Davies, H., Dentro, S., Taniere, P., O'Sullivan, B., Lowe, H.L., Hartley, J.A., Iles, N., Bell, H., Ngai, Y., Shaw, J.A., Herrero, J., Szallasi, Z., Schwarz, R.F., Stewart, A., Quezada, S.A., Le Quesne, J., Van Loo, P., Dive, C., Hackshaw, A. and Swanton, C.
New England Journal of Medicine 376
(22): 2109-2121.
1 June 2017
TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells.
James, D., Levine, A.J., Besser, D. and Hemmati-Brivanlou, A.
Development 132
(6): 1273-1282.
March 2005
Cbl-Associated Protein CAP contributes to correct formation and robust function of the Drosophila heart tube.
Jammrath, J., Reim, I. and Saumweber, H.
PLoS ONE 15
(5): e0233719.
29 May 2020
ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.
Jandrig, B., Seitz, S., Hinzmann, B., Arnold, W., Micheel, B., Koelble, K., Siebert, R., Schwartz, A., Ruecker, K., Schlag, P.M., Scherneck, S. and Rosenthal, A.
Oncogene 23
(57): 9295-9302.
18 October 2004
CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes.
Jang, M.H., Sougawa, N., Tanaka, T., Hirata, T., Hiroi, T., Tohya, K., Guo, Z., Umemoto, E., Ebisuno, Y., Yang, B.G., Seoh, J.Y., Lipp, M., Kiyono, H. and Miyasaka, M.
Journal of Immunology 176
(2): 803-810.
15 January 2006
Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1.
Janke, J., Schlueter, K., Jandrig, B., Theile, M., Koelble, K., Arnold, W., Grinstein, E., Schwartz, A., Estevez-Schwarz, L., Schlag, P.M., Jockusch, B.M. and Scherneck, S.
Journal of Experimental Medicine 191
(10): 1675-1685.
15 May 2000
Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission.
Janssen, J.W., Ludwig, W.D., Borkhardt, A., Spadinger, U., Rieder, H., Fonatsch, C., Hossfeld, D.K., Harbott, J., Schulz, A.S., Repp, R., Sykora, K.W., Hoelzer, D. and Bartram, C.R.
Blood 84
(11): 3835-3842.
1 December 1994
Inhibition of the ER Ca2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis.
Janssen, K., Horn, S., Niemann, M.T., Daniel, P.T., Schulze-Osthoff, K. and Fischer, U.
Journal of Cell Science 122
(Pt 24): 4481-4491.
15 December 2009
Reprogramming of B lymphoid cells in human lymphoma pathogenesis.
Janz, M., Doerken, B. and Mathas, S.
Cell Cycle 5
(10): 1057-1061.
15 May 2006
Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M., Hummel, M., Truss, M., Wollert-Wulf, B., Mathas, S., Joehrens, K., Hagemeier, C., Bommert, K., Stein, H., Doerken, B. and Bargou, R.C.
Blood 107
(6): 2536-2539.
15 March 2006
Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells.
Janz, M., Stuehmer, T., Vassilev, L.T. and Bargou, R.C.
Leukemia 21
(4): 772-779.
April 2007
Semi-automated assembly of high-quality diploid human reference genomes.
Jarvis, E.D., Formenti, G., Rhie, A., Guarracino, A., Yang, C., Wood, J., Tracey, A., Thibaud-Nissen, F., Vollger, M.R., Porubsky, D., Cheng, H., Asri, M., Logsdon, G.A., Carnevali, P., Chaisson, M.J.P., Chin, C.S., Cody, S., Collins, J., Ebert, P., Escalona, M., Fedrigo, O., Fulton, R.S., Fulton, L.L., Garg, S., Gerton, J.L., Ghurye, J., Granat, A., Green, R.E., Harvey, W., Hasenfeld, P., Hastie, A., Haukness, M., Jaeger, E.B., Jain, M., Kirsche, M., Kolmogorov, M., Korbel, J.O., Koren, S., Korlach, J., Lee, J., Li, D., Lindsay, T., Lucas, J., Luo, F., Marschall, T., Mitchell, M.W., McDaniel, J., Nie, F., Olsen, H.E., Olson, N.D., Pesout, T., Potapova, T., Puiu, D., Regier, A., Ruan, J., Salzberg, S.L., Sanders, A.D., Schatz, M.C., Schmitt, A., Schneider, V.A., Selvaraj, S., Shafin, K., Shumate, A., Stitziel, N.O., Stober, C., Torrance, J., Wagner, J., Wang, J., Wenger, A., Xiao, C., Zimin, A.V., Zhang, G., Wang, T., Li, H., Garrison, E., Haussler, D., Hall, I., Zook, J.M., Eichler, E.E., Phillippy, A.M., Paten, B., Howe, K. and Miga, K.H.
Nature 611
(7936): 519-531.
17 November 2022
Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Jayavelu, A.K., Schnöder, T.M., Perner, F., Herzog, C., Meiler, A., Krishnamoorthy, G., Huber, N., Mohr, J., Edelmann-Stephan, B., Austin, R., Brandt, S., Palandri, F., Schröder, N., Isermann, B., Edlich, F., Sinha, A.U., Ungelenk, M., Hübner, C.A., Zeiser, R., Rahmig, S., Waskow, C., Coldham, I., Ernst, T., Hochhaus, A., Jilg, S., Jost, P.J., Mullally, A., Bullinger, L., Mertens, P.R., Lane, S.W., Mann, M. and Heidel, F.H.
Nature 588
(7836): 157-163.
3 December 2020
Efficacy and feasibility of proton beam therapy in relapsed high-risk neuroblastoma-experiences from the prospective KiProReg registry.
Jazmati, D., Hero, B., Thole-Kliesch, T.M., Merta, J., Deubzer, H.E., Bäumer, C., Heinzelmann, F., Schleithoff, S.S., Koerber, F., Eggert, A., Schwarz, R., Simon, T. and Timmermann, B.
Current Oncology 29
(11): 8222-8234.
November 2022
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Jeannet, G., Scheller, M., Scarpellino, L., Duboux, S., Gardiol, N., Back, J., Kuttler, F., Malanchi, I., Birchmeier, W., Leutz, A., Huelsken, J. and Held, W.
Blood 111
(1): 142-149.
1 January 2008
Influence of age, performance status, cancer activity, and IL-6 on anxiety and depression in patients with metastatic breast cancer.
Jehn, C.F., Flath, B., Strux, A., Krebs, M., Possinger, K., Pezzutto, A. and Lueftner, D.
Breast Cancer Research and Treatment 136
(3): 789-794.
December 2012
Influence of comorbidity, age and performance status on treatment efficacy and safety of cetuximab plus irinotecan in irinotecan-refractory elderly patients with metastatic colorectal cancer.
Jehn, C.F., Böning, L., Kröning, H., Pezzutto, A. and Lüftner, D.
European Journal of Cancer 50
(7): 1269-1275.
May 2014
Tricellulin is a target of the ubiquitin ligase Itch.
Jennek, S., Mittag, S., Reiche, J., Westphal, J.K., Seelk, S., Dörfel, M.J., Pfirrmann, T., Friedrich, K., Schütz, A., Heinemann, U. and Huber, O.
Annals of the New York Academy of Sciences 1397
(1): 157-168.
June 2017
Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Jenq, R.R., King, C.G., Volk, C., Suh, D., Smith, O.M., Rao, U.K., Yim, N.L., Holland, A.M., Lu, S.X., Zakrzewski, J.L., Goldberg, G.L., Diab, A., Alpdogan, O., Penack, O., Na, I.K., Kappel, L.W., Wolchok, J.D., Houghton, A.N., Perales, M.A. and van den Brink, M.R.M.
Blood 113
(7): 1574-1580.
12 February 2009
Functional analysis of structural variants in single cells using Strand-seq.
Jeong, H., Grimes, K., Rauwolf, K.K., Bruch, P.M., Rausch, T., Hasenfeld, P., Benito, E., Roider, T., Sabarinathan, R., Porubsky, D., Herbst, S.A., Erarslan-Uysal, B., Jann, J.C., Marschall, T., Nowak, D., Bourquin, J.P., Kulozik, A.E., Dietrich, S., Bornhauser, B., Sanders, A.D. and Korbel, J.O.
Nature Biotechnology 41
(6): 832-844.
June 2023
Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Jerke, U., Marino, S.F., Daumke, O. and Kettritz, R.
Scientific Reports 7
: 43328.
27 February 2017
Development of monoclonal and polyclonal antibodies and an ELISA for the determination of glycodelin in human serum, amniotic fluid and cystic fluid of benign and malignant ovarian tumors.
Jeschke, U., Bischof, A., Speer, R., Briese, V., Richter, D.U., Bergemann, C., Mylonas, I., Shabani, N., Friese, K. and Karsten, U.
Anticancer Research 25
(3): 1581-1589.
1 January 2005
Stimulation of hCG protein and mRNA in first trimester villous cytotrophoblast cells in vitro by glycodelin A.
Jeschke, U., Karsten, U., Reimer, T., Richter, D.U., Bergemann, C., Briese, V., Mylonas, L. and Friese, K.
Journal of Perinatal Medicine 33
(3): 212-218.
1 January 2005
Binding of galectin-1 (gal-1) to the Thomsen-Friedenreich (TF) antigen on trophoblast cells and inhibition of proliferation of trophoblast tumor cells in vitro by gal-1 or an anti-TF antibody.
Jeschke, U., Karsten, U., Wiest, I., Schulze, S., Kuhn, C., Friese, K. and Walzel, H.
Histochemistry and Cell Biology 126
(4): 437-444.
October 2006
Glycodelin A and differentiation of first trimester trophoblast cells in vitro.
Jeschke, U., Richter, D.U., Reimer, T., Bergemann, C., Briese, V., Karsten, U., Mylonas, I., Kupka, M.S., Wiest, I. and Friese, K.
Archives of Gynecology and Obstetrics 272
(2): 151-159.
1 August 2005
Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions.
Jeuthe, S., Kemna, J., Kemna, C.P., Zocholl, D., Klopfleisch, R., Palme, R., Kirschbaum, C., Thoene-Reineke, C. and Kammertoens, T.
PLoS ONE 15
(9): e0239231.
30 September 2020
Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses.
Jiang, B., Schmitt, M.J., Rand, U., Company, C., Dramaretska, Y., Grossmann, M., Serresi, M., Cicin-Sain, L. and Gargiulo, G.
Science Advances 9
(25): eadf4975.
23 June 2023
TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression.
Jiang, C., Zhu, Y., Zhou, Z., Gumin, J., Bengtsson, L., Wu, W., Songyang, Z., Lang, F.F. and Lin, X.
Oncogene 36
(20): 2813-2823.
18 May 2017
In vitro functionality and endurance of GMP-compliant point-of-care BCMA.CAR-T cells at different timepoints of cryopreservation.
Jiang, G., Neuber, B., Hückelhoven-Krauss, A., Höpken, U., Ding, Y., Sedloev, D., Wang, L., Reichman, A., Eberhardt, F., Wermke, M., Rehm, A., Müller-Tidow, C., Schmitt, A. and Schmitt, M.
International Journal of Molecular Sciences 25
(3): 1394.
23 January 2024
Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.
Jiang, S., Penack, O., Terzer, T., Schult, D., Majer-Lauterbach, J., Radujkovic, A., Blau, I.W., Bullinger, L., Müller-Tidow, C., Dreger, P. and Luft, T.
Haematologica 106
(2): 446-453.
February 2020
MicroRNA-17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways.
Jin, H.Y., Oda, H., Lai, M., Skalsky, R.L., Bethel, K., Shepherd, J., Kang, S.G., Liu, W.H., Sabouri-Ghomi, M., Cullen, B.R., Rajewsky, K. and Xiao, C.
EMBO Journal 32
(17): 2377-2391.
28 August 2013
Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H., Kase, J., Dörr, J.R., Milanovic, M., Lenze, D., Grau, M., Beuster, G., Ji, S., Reimann, M., Lenz, P., Hummel, M., Doerken, B., Lenz, G., Scheidereit, C., Schmitt, C.A. and Lee, S.
Genes & Development 25
(20): 2137-2146.
15 October 2011
Accelerating clinical scale production of BCMA CAR T cells with defined maturation stages.
Joedicke, J.J., Großkinsky, U., Gerlach, K., Künkele, A., Höpken, U.E. and Rehm, A.
Molecular Therapy - Methods and Clinical Development 24
: 181-198.
10 March 2022
Sulfated polysaccharide anticoagulants suppress natural killer cell activity in vitro.
Johann, S., Zoller, C., Haas, S., Bluemel, G., Lipp, M. and Foerster, R.
Thrombosis and Haemostasis 74
(4): 998-1002.
October 1995
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level.
John, L., Poos, A.M., Brobeil, A., Schinke, C., Huhn, S., Prokoph, N., Lutz, R., Wagner, B., Zangari, M., Tirier, S.M., Mallm, J.P., Schumacher, S., Vonficht, D., Solé-Boldo, L., Quick, S., Steiger, S., Przybilla, M.J., Bauer, K., Baumann, A., Hemmer, S., Rehnitz, C., Lückerath, C., Sachpekidis, C., Mechtersheimer, G., Haberkorn, U., Dimitrakopoulou-Strauss, A., Reichert, P., Barlogie, B., Müller-Tidow, C., Goldschmidt, H., Hillengass, J., Rasche, L., Haas, S.F., van Rhee, F., Rippe, K., Raab, M.S., Sauer, S. and Weinhold, N.
Nature Communications 14
(1): 5011.
17 August 2023
The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-mediated immune responses.
Jongsma, M.L.M., de Waard, A.A., Raaben, M., Zhang, T., Cabukusta, B., Platzer, R., Blomen, V.A., Xagara, A., Verkerk, T., Bliss, S., Kong, X., Gerke, C., Janssen, L., Stickel, E., Holst, S., Plomp, R., Mulder, A., Ferrone, S., Claas, F.H.J., Heemskerk, M.H.M, Griffioen, M., Halenius, A., Overkleeft, H., Huppa, J.B., Wuhrer, M., Brummelkamp, T.R., Neefjes, J. and Spaapen, R.M.
Immunity 54
(1): 132-150.e9.
12 January 2021
Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence.
Joseph, B., Schneiker-Bekel, S., Schramm-Glueck, A., Blom, J., Claus, H., Linke, B., Schwarz, R.F., Becker, A., Goesmann, A., Frosch, M. and Schoen, C.
Journal of Bacteriology 192
(20): 5363-5377.
October 2010
Virulence evolution of the human pathogen Neisseria meningitidis by recombination in the core and accessory genome.
Joseph, B., Schwarz, R.F., Linke, B., Blom, J., Becker, A., Claus, H., Goesmann, A., Frosch, M., Mueller, T., Vogel, U. and Schoen, C.
PLoS ONE 6
(4): e18441.
26 April 2011
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi, K., de Massy, M.R., Ismail, M., Reading, J.L., Uddin, I., Woolston, A., Hatipoglu, E., Oakes, T., Rosenthal, R., Peacock, T., Ronel, T., Noursadeghi, M., Turati, V., Furness, A.J.S., Georgiou, A., Wong, Y.N.S., Ben Aissa, A., Sunderland, M.W., Jamal-Hanjani, M., Veeriah, S., Birkbak, N.J., Wilson, G.A., Hiley, C.T., Ghorani, E., Guerra-Assunção, J.A., Herrero, J., Enver, T., Hadrup, S.R., Hackshaw, A., Peggs, K.S., McGranahan, N., Swanton, C., Quezada, S.A. and Chain, B.
Nature Medicine 25
(10): 1549-1559.
October 2019
Long noncoding RNA lISPR1 is required for S1P signaling and endothelial cell function.
Josipovic, I., Pflueger, B., Fork, C., Vasconez, A.E., Oo, J.A., Hitzel, J., Seredinski, S., Gamen, E., Heringdorf, D.M.Z., Chen, W., Looso, M., Pullamsetti, S.S., Brandes, R.P. and Leisegang, M.S.
Journal of Molecular and Cellular Cardiology 116
: 57-68.
March 2018
Morphologie gastrointestinaler Stromatumoren im fortgeschrittenen Stadium der Erkrankung: Ausgangsbefunde vor Chemotherapie mit Imatinib [Morphology of gastrointestinal stromal tumors in advanced stages of the disease: baseline findings before chemotherapy with imatinib].
Jost, D., Stroszczynski, C., Chmelik, P., Gaffke, G., Schlecht, I., Pink, D., Reichardt, P., Schneider, U., Hohenberger, P. and Felix, R.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 175
: 791-798.
1 June 2003
Cologne high-dose sequential chemotherapy in relapsed and refractory Hodgkin lymphoma: results of a large multicenter study of the German Hodgkin Lymphoma Study Group (GHSG).
Josting, A., Rudolph, C., Mapara, M., Glossmann, J.P., Sieniawski, M., Sieber, M., Kirchner, H.H., Doerken, B., Hossfeld, D.K., Kisro, J., Metzner, B., Berdel, W.E., Diehl, V. and Engert, A.
Annals of Oncology 16
: 116-123.
1 January 2005
High-dose sequential chemotherapy followed by autologous stem cell transplantation in relapsed and refractory aggressive non-Hodgkin's lymphoma: results of a multicenter phase II study.
Josting, A., Sieniawski, M., Glossmann, J.P., Staak, O., Nogova, L., Peters, N., Mapara, M., Doerken, B., Ko, Y., Metzner, B., Kisro, J., Diehl, V. and Engert, A.
Annals of Oncology 16
: 1359-1365.
1 January 2005
Towards determining the differentiation program of antigen-presenting dentritic cells by transcriptional profiling.
Ju, X.S., Hacker, C., Kurz, S.M., Knespel, S., Blendinger, G., Rose-John, S. and Zenke, M.
European Journal of Cell Biology 82
(2): 75-86.
February 2003
Immunoglobulin-like transcripts ILT2, ILT3 and ILT7 are expressed by human dendritic cells and down-regulated following activation.
Ju, X.S., Hacker, C., Scherer, B., Redecke, V., Berger, T., Schuler, G., Wagner, H., Lipford, G.B. and Zenke, M.
Gene 331
(1-2): 159-164.
28 April 2004
Differentiation of human antigen-presenting dendritic cells from CD34+ hematopoietic stem cells in vitro.
Ju, X.S. and Zenke, M.
Methods in Molecular Biology 215
: 399-407.
2003
YB-1 as a cell cycle-regulated transcription factor facilitating cyclin A and cyclin B1 gene expression.
Juerchott, K., Bergmann, S., Stein, U., Walther, W., Janz, M., Manni, I., Piaggio, G., Fietze, E., Dietel, M. and Royer, H.D.
Journal of Biological Chemistry 278
(30): 27988-27996.
1 January 2003
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Juerchott, K., Kuban, R.J., Krech, T., Blüthgen, N., Stein, U., Walther, W., Friese, C., Kielbasa, S.M., Ungethuem, U., Lund, P., Knoesel, T., Kemmner, W., Morkel, M., Fritzmann, J., Schlag, P.M., Birchmeier, W., Krueger, T., Sperling, S., Sers, C., Royer, H.D., Herzel, H. and Schaefer, R.
PLoS Genetics 6
(12): e1001231.
2 December 2010
Vascular endothelial growth factor-D and its receptor VEGFR-3: Two novel independent prognostic markers in gastric adenocarcinoma.
Juettner, S., Wissmann, C., Joens, T., Vieth, M., Hertel, J., Gretschel, S., Schlag, P.M., Kemmner, W. and Hoecker, M.
Journal of Clinical Oncology 24
(2): 228-240.
10 January 2006
Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes.
Jumaa, H., Caganova, M., McAllister, E.J., Hoenig, L., He, X., Saltukoglu, D., Brenker, K., Köhler, M., Leben, R., Hauser, A.E., Niesner, R., Rajewsky, K., Reth, M. and Jellusova, J.
Life Science Alliance 3
(6): e202000700.
June 2020
Inference of differentiation trajectories by transfer learning across biological processes.
Jumde, G., Spanjaard, B. and Junker, J.P.
Cell Systems 15
(1): 75-82.e5.
17 January 2024
Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma.
Jundt, F., Acikgoez, O., Kwon, S.H., Schwarzer, R., Anagnostopoulos, I., Wiesner, B., Mathas, S., Hummel, M., Stein, H., Reichardt, H.M. and Doerken, B.
Leukemia 22
(8): 1587-1594.
August 2008
Trimethoprim-sulfamethoxazole exacerbates posthypoxic action myoclonus in a patient with suspicion of Pneumocystis jiroveci infection.
Jundt, F., Lempert, T., Doerken, B. and Pezzutto, A.
Infection 32
(3): 176-178.
1 June 2004
A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F., Raetzel, N., Mueller, C., Calkhoven, C.F., Kley, K., Mathas, S., Lietz, A., Leutz, A. and Doerken, B.
Blood 106
: 1801-1807.
1 January 2005
Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F., Schulze-Proebsting, K., Anagnostopoulos, I., Muehlinghaus, G., Chatterjee, M., Mathas, S., Bargou, R.C., Manz, R., Stein, H. and Doerken, B.
Blood 103
(9): 3511-3515.
1 January 2004
Promoter identification and transcriptional regulation of the metastasis gene MACC1 in colorectal cancer.
Juneja, M., Ilm, K., Schlag, P.M. and Stein, U.
Molecular Oncology 7
(5): 929-943.
October 2013
Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.
Juneja, M., Kobelt, D., Walther, W., Voss, C., Smith, J., Specker, E., Neuenschwander, M., Gohlke, B.O., Dahlmann, M., Radetzki, S., Preissner, R., von Kries, J.P., Schlag, P.M. and Stein, U.
PLoS Biology 15
(6): e2000784.
1 June 2017
Proteine unter Druck.
Jung, C.
BioForum 27
(9): 48-49.
1 January 2004
High pressure Fourier transform infrared (FT-IR) spectroscopic studies on inducible nitric oxide (NO) synthase active site: A comparison to cytochrome P450cam.
Jung, C. and Ghosh, D.K.
Cellular and Molecular Biology 50
(4): 335-346.
1 January 2004
Compressibility and uncoupling of cytochrome P450cam: high pressure FTIR and activity studies.
Jung, C., Kozin, S.A., Canny, B., Chervin, J.C. and Hoa, G.H.
Biochemical and Biophysical Research Communications 312
(1): 197-203.
5 December 2003
Multi-frequency EPR and Moessbauer spectroscopic studies on freeze-quenched reaction intermediates of nitric oxide synthase.
Jung, C., Lendzian, F., Schuenemann, V., Richter, M., Boettger, L.H., Trautwein, A.X., Contzen, J., Galander, M., Ghosh, D.K. and Barra, A.L.
Magnetic Resonance in Chemistry : MRC 43
: S84-S95.
18 October 2005
Spectroscopic characterization of the iron-oxo intermediate in cytochrome P450.
Jung, C., Schuenemann, V., Lendzian, F., Trautwein, A.X., Contzen, J., Galander, M., Boettger, L.H., Richter, M. and Barra, A.L.
Biological Chemistry 386
(10): 1043-1053.
1 October 2005
Strong immunogenic potential of a B7 retroviral expression vector: Generation of HLA-B7-restricted CTL response against selectable marker genes.
Jung, D., Jaeger, E., Cayeux, S., Blankenstein, T., Hilmes, C., Karbach, J., Moebius, U., Knuth, A., Huber, C. and Seliger, B.
Human Gene Therapy 9
: 53-62.
1 January 1998
Influence of substrate binding on the mechanical stability of mouse dihydrofolate reductase.
Junker, J.P., Hell, K., Schlierf, M., Neupert, W. and Rief, M.
Biophysical Journal 89
(5): L46-L48.
November 2005
A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.
Junker, J.P., Peterson, K.A., Nishi, Y., Mao, J., McMahon, A.P. and van Oudenaarden, A.
Developmental Cell 31
(4): 448-460.
24 November 2014
Evidence for a broad transition-state ensemble in calmodulin folding from single-molecule force spectroscopy.
Junker, J.P. and Rief, M.
Angewandte Chemie International Edition 49
(19): 3306-3309.
26 April 2010
Single-molecule force spectroscopy distinguishes target binding modes of calmodulin.
Junker, J.P. and Rief, M.
Proceedings of the National Academy of Sciences of the United States of America 106
(34): 14361-14366.
25 August 2009
Ligand-dependent equilibrium fluctuations of single calmodulin molecules.
Junker, J.P., Ziegler, F. and Rief, M.
Science 323
(5914): 633-637.
30 January 2009
Genome-wide RNA tomography in the zebrafish embryo.
Junker, J.P., Noël, E.S., Guryev, V., Peterson, K.A., Shah, G., Huisken, J., McMahon, A.P., Berezikov, E., Bakkers, J. and van Oudenaarden, A.
Cell 159
(3): 662-675.
23 October 2014
CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses.
Junt, T., Fink, K., Foerster, R., Senn, B., Lipp, M., Muramatsu, M., Zinkernagel, R.M., Ludewig, B. and Hengartner, H.
Journal of Immunology 175
(11): 7109-7116.
1 December 2005
Impact of CCR7 on priming and distribution of antiviral effector and memory CTL.
Junt, T., Scandella, E., Foerster, R., Krebs, P., Krautwald, S., Lipp, M., Hengartner, H. and Ludewig, B.
Journal of Immunology 173
(11): 6684-6693.
1 January 2004
Crystal structures of the single PDZ domains from GRASP65 and their interaction with the golgin GM130.
Jurk, C.M., Roske, Y. and Heinemann, U.
Croatica Chemica Acta 91
(2): 255-264.
June 2018
Immunhistochemische Analyse von Bcl-2, nukleärem S100A4, MITF und Ki67 zur Risikostratifizierung von Melanomen im Frühstadium - ein kombinierter immunhistochemischer Score.
Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17
(8): 800-809.
August 2019
Immunohistochemical analysis of Bcl-2, nuclear S100A4, MITF and Ki67 for risk stratification of early-stage melanoma - a combined IHC score for melanoma risk stratification.
Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17
(8): 800-808.
August 2019
A cellular platform for the evaluation of immune checkpoint molecules.
Jutz, S., Hennig, A., Paster, W., Asrak, Ö., Dijanovic, D., Kellner, F., Pickl, W.F., Huppa, J.B., Leitner, J. and Steinberger, P.
Oncotarget 8
(39): 64892-64906.
12 September 2017
Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-κB, NFAT and AP-1.
Jutz, S., Leitner, J., Schmetterer, K., Doel-Perez, I., Majdic, O., Grabmeier-Pfistershammer, K., Paster, W., Huppa, J.B. and Steinberger, P.
Journal of Immunological Methods 430
: 10-20.
March 2016
Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.
Jutzi, J.S., Basu, T., Pellmann, M., Kaiser, S., Steinemann, D., Sanders, M.A., Hinai, A.S.A., Zeilemaker, A., Bojtine Kovacs, S., Koellerer, C., Ostendorp, J., Aumann, K., Wang, W., Raffoux, E., Cassinat, B., Bullinger, L., Schlegelberger, B., Valk, P.J.M. and Pahl, H.L.
Blood 133
(16): 1766-1777.
18 April 2019
Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.
Kabrani, E., Chu, V.T., Tasouri, E., Sommermann, T., Baßler, K., Ulas, T., Zenz, T., Bullinger, L., Schultze, J.L., Rajewsky, K. and Sander, S.
Blood 132
(25): 2670-2683.
20 December 2018
Development of mouse model systems of germinal center lymphomas.
Kabrani, E. and Sander, S.
Methods in Molecular Biology 1623
: 233-242.
2017
Significant reduced loss of bone mineral density after four vs. six cycles of R-CHOP: an analysis of the FLYER-trial.
Kaddu-Mulindwa, D., Lesan, V., Berdel, C., Stilgenbauer, S., Bewarder, M., Thurner, L., Witzens-Harig, M., Viardot, A., Soekler, M., Keller, U., Truemper, L., Christofyllakis, K., Fleser, O., Bittenbring, J.T., Poeschel, V., Held, G. and Jagoda, P.
Leukemia & Lymphoma 63
(2): 326-334.
February 2022
Cytotoxic effects of rabbit anti-thymocyte globulin preparations on primary human thymic epithelial cells.
Kaebisch, E.M., Cho, M.Y., Oh, Y.S., Olfe, L.I., Szyska, M., Becker, S.C., Reinke, P., Volk, H.D., Gillissen, B., Bullinger, L., Thiel, A. and Na, I.K.
Transplantation 103
(11): 2234-2244.
November 2019
JAK2 V617F allele burden quantified by real time quantitative polymerase chain reaction and competitive polymerase chain reaction in patients with chronic myeloproliferative neoplasia.
Kaeda, J., Bonamino, M., Ayres-Silva, J., Solza, C., Ringel, F., Blau, O., Daumas, A., Oberender, C., Doerken, B., Le Coutre, P. and Zalcberg, I.
Leukemia & Lymphoma 55
(1): 128-135.
January 2014
Longitudinal study to assess the clinical significance of MSI2 expression in chronic myeloid keukemia patients.
Kaeda, J., Ringel, F., Oberender, C., Gresse, M., Amini, L., Schwarz, M., Doerken, B. and le Coutre, P.
Acta Haematologica 136
(1): 62-64.
June 2016
Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.
Kaeda, J., Ringel, F., Oberender, C., Mills, K., Quintarelli, C., Pane, F., Koschmieder, S., Slany, R., Schwarzer, R., Saglio, G., Hemmati, P., van Lessen, A., Amini, L., Greese, M., Vagge, E., Burmeister, T., Serra, A., Carson, A., Schwarz, M., Westermann, J., Jundt, F., Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 56
(7): 2105-2113.
July 2015
Cellular senescence in cancer treatment: friend or foe?
Kahlem, P., Doerken, B. and Schmitt, C.A.
Journal of Clinical Investigation 113
(2): 169-174.
January 2004
Mycobacterium tuberculosis triggers formation of lymphoid structure in murine lungs.
Kahnert, A., Höpken, U.E., Stein, M., Bandermann, S., Lipp, M. and Kaufmann, S.H.
Journal of Infectious Diseases 195
(1): 46-54.
1 January 2007
Reduced tumor-antigen density leads to PD-1/PD-L1 mediated impairment of partially exhausted CD8(+) T cells.
Kaiser, A.D., Schuster, K., Gadiot, J., Borkner, L., Daebritz, H., Schmitt, C., Andreesen, R. and Blank, C.
European Journal of Immunology 42
(3): 662-671.
March 2012
The influence of capsaicin on the integrity of microvascular endothelial cell monolayers.
Kaiser, M., Burek, M., Britz, S., Lankamp, F., Ketelhut, S., Kemper, B., Förster, C., Gorzelanny, C. and Goycoolea, F.M.
International Journal of Molecular Sciences 20
(1): 122.
30 December 2018
Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
Kaji, T., Ishige, A., Hikida, M., Taka, J., Hijikata, A., Kubo, M., Nagashima, T., Takahashi, Y., Kurosaki, T., Okada, M., Ohara, O., Rajewsky, K. and Takemori, T.
Journal of Experimental Medicine 209
(11): 2079-2097.
22 October 2012
Binding of ribosomes to the rough endoplasmic reticulum mediated by the sec61p-complex.
Kalies, K.U., Goerlich, D. and Rapoport, T.A.
Journal of Cell Biology 126
(4): 925-934.
August 1994
Gene expression divergence recapitulates the developmental hourglass model.
Kalinka, A.T., Varga, K.M., Gerrard, D.T., Preibisch, S., Corcoran, D.L., Jarrells, J., Ohler, U., Bergman, C.M. and Tomancak, P.
Nature 468
(7325): 811-814.
9 December 2010
Identification of miR-21-5p and miR-210-3p serum levels as biomarkers for patients with papillary renal cell carcinoma: a multicenter analysis.
Kalogirou, C., Ellinger, J., Kristiansen, G., Hatzichristodoulou, G., Kübler, H., Kneitz, B., Busch, J. and Fendler, A.
Translational Andrology and Urology 9
(3): 1314-1322.
June 2020
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.
Kamdem, N., Roske, Y., Kovalskyy, D., Platonov, M.O., Balinskyi, O., Kreuchwig, A., Saupe, J., Fang, L., Diehl, A., Schmieder, P., Krause, G., Rademann, J., Heinemann, U., Birchmeier, W. and Oschkinat, H.
Magnetic Resonance 2
(1): 355-374.
2 June 2021
Making and circumventing tolerance to cancer.
Kammertoens, T. and Blankenstein, T.
European Journal of Immunology 39
(9): 2345-2353.
September 2009
B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin).
Kammertoens, T., Qin, Z., Briesemeister, D., Bendelac, A. and Blankenstein, T.
International Journal of Cancer 131
(7): 1499-1508.
1 October 2012
CY15, a malignant histiocytic tumor that is phenotypically similar to immature dendritic cells.
Kammertoens, T., Willebrand, R., Erdmann, B., Li, L., Li, Y., Engels, B., Uckert, W. and Blankenstein, T.
Cancer Research 65
: 2560-2564.
1 January 2005
Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T., Friese, C., Arina, A., Idel, C., Briesemeister, D., Rothe, M., Ivanov, A., Szymborska, A., Patone, G., Kunz, S., Sommermeyer, D., Engels, B., Leisegang, M., Textor, A., Fehling, H.J., Fruttiger, M., Lohoff, M., Herrmann, A., Yu, H., Weichselbaum, R., Uckert, W., Hübner, N., Gerhardt, H., Beule, D., Schreiber, H. and Blankenstein, T.
Nature 545
(7652): 98-102.
4 May 2017
M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation.
Kandalla, P.K., Sarrazin, S., Molawi, K., Berruyer, C., Redelberger, D., Favel, A., Bordi, C., de Bentzmann, S. and Sieweke, M.H.
Journal of Experimental Medicine 213
(11): 2269-2279.
10 October 2016
Bacteriophage tailspikes and bacterial O-antigens as a model system to study weak-affinity protein-polysaccharide interactions.
Kang, Y., Gohlke, U., Engström, O., Hamark, C., Scheidt, T., Kunstmann, S., Heinemann, U., Widmalm, G., Santer, M. and Barbirz, S.
Journal of the American Chemical Society 138
(29): 9109-9118.
27 July 2016
BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M., Lin, M., Maertzdorf, J., Heuberger, J., Muellerke, S., Zuo, X., Vidal, R., Shureiqi, I., Fischer, A.S., Sauer, S., Berger, H., Kidess, E., Mollenkopf, H.J., Tacke, F., Meyer, T.F. and Sigal, M.
Nature Communications 13
(1): 1577.
24 March 2022
Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Kapp-Schwoerer, S., Weber, D., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Krönke, J., Theis, F., Rücker, F.G., Teleanu, M.V., Panina, E., Jahn, N., Herzig, J., Kubanek, L., Schrade, A., Göhring, G., Fiedler, W., Kindler, T, Schroeder, T., Mayer, K.T., Lübbert, M., Wattad, M., Götze, K.S., Horst, H.A., Koller, E., Wulf, G., Schleicher, J., Bentz, M., Krauter, J., Bullinger, L., Krzykalla, J., Benner, A., Schlenk, R.F., Thol, F., Heuser, M., Ganser, A., Döhner, H and Döhner, K.
Blood 136
(26): 3041-3050.
24 December 2020
Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling.
Karabacak Calviello, A., Hirsekorn, A., Wurmus, R., Yusuf, D. and Ohler, U.
Genome Biology 20
(1): 42.
21 February 2019
Adjuvants and vaccines used in allergen-specific immunotherapy induce neutrophil extracellular traps.
Karacs, J., Reithofer, M., Kitzmüller, C., Kraller, M., Schmalz, S., Bleichert, S., Huppa, J.B., Stockinger, H., Bohle, B. and Jahn-Schmid, B.
Vaccines 9
(4): 321.
1 April 2021
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx.
Karasaki, T., Moore, D.A., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Magno, N., Ward, S., Bakir, M.A., Watkins, T.B.K., Grigoriadis, K., Huebner, A., Hill, M.S., Frankell, A.M., Abbosh, C., Puttick, C., Zhai, H., Gimeno-Valiente, F., Saghafinia, S., Kanu, N., Dietzen, M., Pich, O., Lim, E.., Martínez-Ruiz, C., Black, J.R.M., Biswas, D., Campbell, B.B., Lee, C., Colliver, E., Enfield, K.S.S., Hessey, S., Hiley, C.T., Zaccaria, S., Litchfield, K., Birkbak, N.J., Cadieux, E.L., Demeulemeester, J., Van Loo, P., Adusumilli, P.S., Tan, K.S., Cheema, W., Sanchez-Vega, F., Jones, D.R., Rekhtman, N., Travis, W.D., Hackshaw, A., Marafioti, T., Salgado, R., Le Quesne, J., Nicholson, A.G., McGranahan, N., Swanton, C. and Jamal-Hanjani, M.
Nature Medicine 29
(4): 833-845.
April 2023
Antibodies to the alpha(1)-adrenergic receptor cause vascular impairments in rat brain as demonstrated by magnetic resonance angiography.
Karczewski, P., Pohlmann, A., Wagenhaus, B., Wisbrun, N., Hempel, P., Lemke, B., Kunze, R., Niendorf, T. and Bimmler, M.
PLoS ONE 7
(7): e41602.
30 July 2012
Recruitment of histone methyltransferase Ehmt1 to Foxp3 TSDR counteracts differentiation of induced regulatory T cells.
Karl, M., Sommer, C., Gabriel, C.H., Hecklau, K., Venzke, M., Hennig, A.F., Radbruch, A., Selbach, M. and Baumgrass, R.
Journal of Molecular Biology 431
(19): 3606-3625.
6 September 2019
Enhanced binding of antibodies to the DTR motif of MUC1 tandem repeat peptide is mediated by site-specific glycosylation.
Karsten, U., Diotel, C., Klich, G., Paulsen, H., Goletz, S., Mueller, S. and Hanisch, F.G.
Cancer Research 58
(12): 2541-2549.
15 June 1998
Binding patterns of DTR-specific antibodies reveal a glycosylation-conditioned tumor-specific epitope of the epithelial mucin (MUC1).
Karsten, U., Serttas, N., Paulsen, H., Danielczyk, A. and Goletz, S.
Glycobiology 14
(8): 681-692.
1 August 2004
What makes MUC1 a tumor antigen?
Karsten, U., von Mensdorff-Pouilly, S. and Goletz, S.
Tumor Biology 26
(4): 217-220.
6 July 2005
Solvation oscillations and excited-state dynamics of 2-amino- and 2-hydroxy-7-nitrofluorene and its 2'-deoxyriboside.
Karunakaran, V., Pfaffe, M., Ioffe, I., Senyushkina, T., Kovalenko, S.A., Mahrwald, R., Fartzdinov, V., Sklenar, H. and Ernsting, N.P.
Journal of Physical Chemistry A 112
(18): 4294-4307.
8 May 2008
Identifying ischemic stroke associated with cancer: a multiple model derived from a case-control analysis.
Kassubek, R., Bullinger, L., Kassubek, J., Dreyhaupt, J., Ludolph, A.C., Althaus, K. and Lewerenz, J.
Journal of Neurology 264
(4): 781-791.
April 2017
mRNA interactome capture in mammalian cells.
Kastelic, N. and Landthaler, M.
Methods 126
: 38-43.
15 August 2017
Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath, J., Du, W., Pruene, A., Braun, T., Thommandru, B., Turk, R., Sturgeon, M.L., Kurgan, G.L., Amini, L., Stein, M., Zittel, T., Martini, S., Ostendorf, L., Wilhelm, A., Akyüz, L., Rehm, A., Hoepken, U.E., Pruß, A., Künkele, A., Jacobi, A.M., Volk, H.D., Schmueck-Henneresse, M., Stripecke, R., Reinke, P. and Wagner, D.L.
Molecular Therapy - Methods and Clinical Development 25
: 311-330.
9 June 2022
The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.
Katz, S., Kowenz-Leutz, E., Mueller, C., Meese, K., Ness, S.A. and Leutz, A.
EMBO Journal 12
(4): 1321-1332.
April 1993
The Drosophila translational control element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes.
Katzenberger, R.J., Rach, E.A., Anderson, A.K., Ohler, U. and Wassarman, D.A.
PLoS ONE 7
(9): e45009.
11 September 2012
Frog Prince transposon-based RNAi vectors mediate efficient gene knockdown in human cells.
Kaufman, C.D., Izsvak, Z., Katzer, A. and Ivics, Z.
Journal of RNAi and Gene Silencing 1
(2): 97-104.
October 2005
Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.
Kaufman, W.L., Kocman, I., Agrawal, V., Rahn, H.P., Besser, D. and Gossen, M.
Nucleic Acids Research 36
(17): e111.
October 2008
Identification of early neurodegenerative pathways in progressive multiple sclerosis.
Kaufmann, M., Schaupp, A.L., Sun, R., Coscia, F., Dendrou, C.A., Cortes, A., Kaur, G., Evans, H.G., Mollbrink, A., Navarro, J.F., Sonner, J.K., Mayer, C., DeLuca, G.C., Lundeberg, J., Matthews, P.M., Attfield, K.E., Friese, M.A., Mann, M. and Fugger, L.
Nature Neuroscience 25
(7): 944-955.
July 2022
MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.
Kaufmann, T.L., Petkovic, M., Watkins, T.B.K., Colliver, E.C., Laskina, S., Thapa, N., Minussi, D.C., Navin, N., Swanton, C., Van Loo, P., Haase, K., Tarabichi, M. and Schwarz, R.F.
Genome Biology 23
(1): 241.
14 November 2022
Poly(ethylene oxide)-block-poly(glutamic acid) coated maghemite nanoparticles: in vitro characterization and in vivo behaviour.
Kaufner, L., Cartier, R., Wuestneck, R., Fichtner, I., Pietschmann, S., Bruhn, H., Schuett, D., Thuenemann, A.F. and Pison, U.
Nanotechnology 18
(11): 115710.
21 March 2007
The role of CCR7 in allergic airway inflammation induced by house dust mite exposure.
Kawakami, M., Narumoto, O., Matsuo, Y., Horiguchi, K., Horiguchi, S., Yamashita, N., Sakaguchi, M., Lipp, M., Nagase, T. and Yamashita, N.
Cellular Immunology 275
(1-2): 24-32.
January 2012
Regional regulation of filiform tongue papillae development by Ikkα/Irf6.
Kawasaki, M., Kawasaki, K., Oommen, S., Blackburn, J., Watanabe, M., Nagai, T., Kitamura, A., Maeda, T., Liu, B., Schmidt-Ullrich, R., Akiyama, T., Inoue, J.I., Hammond, N.L., Sharpe, P.T. and Ohazama, A.
Developmental Dynamics 245
(9): 937-946.
September 2016
Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia.
Kayser, S., Martínez-Cuadrón, D., Rodriguez-Veiga, R., Hänel, M., Tormo, M., Schäfer-Eckart, K., Botella, C., Stölzel, F., Del Castillo, T.B., Keller, U., Rodriguez-Medina, C., Held, G., Amigo, M.L., Schliemann, C., Colorado, M., Kaufmann, M., Garcia, M.B., Krause, S.W., Görner, M., Jost, E., Steffen, B., Zukunft, S., Platzbecker, U., Ho, A.D., Baldus, C.D., Serve, H., Müller-Tidow, C., Thiede, C., Bornhäuser, M., Montesinos, P., Röllig, C. and Schlenk, R.F.
Haematologica 108
(8): 2059-2066.
August 2023
Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide - an international collaborative study.
Kayser, S., Schlenk, R.F., Lebon, D., Carre, M., Götze, K.S., Stölzel, F., Berceanu, A., Schäfer-Eckart, K., Peterlin, P., Hicheri, Y., Rahme, R., Raffoux, E., Chermat, F., Krause, S.W., Aulitzky, W.E., Rigaudeau, S., Noppeney, R., Berthon, C., Görner, M., Jost, E., Carassou, P., Keller, U., Orvain, C., Braun, T., Saillard, C., Arar, A., Kunzmann, V., Wemeau, M., De Wit, M., Niemann, D., Bonmati, C., Schwänen, C., Abraham, J., Aljijakli, A., Haiat, S., Krämer, A., Reichle, A., Gnadler, M., Willekens, C., Spiekermann, K., Hiddemann, W., Müller-Tidow, C., Thiede, C., Röllig, C., Serve, H., Bornhäuser, M., Baldus, C.D., Lengfelder, E., Fenaux, P., Platzbecker, U. and Adès, L.
Haematologica 106
(12): 3100-3106.
December 2021
Efficient determination of the accessible conformation space of multi-domain complexes based on EPR PELDOR data.
Kazemi, S., Lopata, A., Kniss, A., Pluska, L., Güntert, P., Sommer, T., Prisner, T.F., Collauto, A. and Dötsch, V.
Journal of Biomolecular NMR 77
(5-6): 261-269.
December 2023
Evidence that ternary complex (eIF2-GTP-tRNAiMet)-deficient preinitiation complexes are core constituents of mammalian stress granules.
Kedersha, N., Chen, S., Gilks, N., Li, W., Miller, I.J., Stahl, J. and Anderson, P.
Molecular Biology of the Cell 13
(1): 195-210.
January 2002
Nuclear pore complex components in the malaria parasite Plasmodium berghei.
Kehrer, J., Kuss, C., Andres-Pons, A., Reustle, A., Dahan, N., Devos, D., Kudryashev, M., Beck, M., Mair, G.R. and Frischknecht, F.
Scientific Reports 8
(1): 11249.
26 July 2018
Effect of surface modified liposomes on the aggregation of platelets and tumor cells.
Keil, C., Zeisig, R. and Fichtner, I.
Thrombosis and Haemostasis 94
(2): 404-411.
August 2005
Transcriptional expression profile of cultured human embryonic stem cells in vitro and in vivo.
Keil, M., Siegert, A., Eckert, K., Gerlach, J., Haider, W. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 48
(3): 165-174.
March 2012
Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
Keilhack, H., Mueller, M., Boehmer, S.A., Frank, C., Weidner, K.M., Birchmeier, W., Ligensa, T., Berndt, A., Kosmehl, H., Gunther, B., Mueller, T., Birchmeier, C. and Boehmer, F.D.
Journal of Cell Biology 152
(2): 325-334.
22 January 2001
Loss of UDP-N-acetylglucosamine 2-epimerase/ N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells.
Kemmner, W., Kessel, P., Sanchez-Ruderisch, H., Moeller, H., Hinderlich, S., Schlag, P.M. and Detjen, K.
FASEB Journal 26
(2): 938-946.
February 2012
Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays.
Kemmner, W., Roefzaad, C., Haensch, W. and Schlag, P.M.
Biochimica et Biophysica Acta - General Subjects 1621
(3): 272-279.
11 June 2003
Die Molekuele der Metastasierung [the molecules of metastasis].
Kemmner, W. and Schlag, P.M.
Chirurgische Praxis 61
: 203-212.
1 January 2003
Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer.
Kemmner, W., Wan, K., Ruttinger, S., Ebert, B., Macdonald, R., Klamm, U. and Moesta, K.T.
FASEB Journal 22
(2): 500-509.
February 2008
IFNγ binding to extracellular matrix prevents fatal systemic toxicity.
Kemna, J., Gout, E., Daniau, L., Lao, J., Weißert, K., Ammann, S., Kühn, R., Richter, M., Molenda, C., Sporbert, A., Zocholl, D., Klopfleisch, R., Schütz, A., Lortat-Jacob, H., Aichele, P., Kammertoens, T. and Blankenstein, T.
Nature Immunology 24
(3): 414-422.
March 2023
The other site of rhabdomyosarcoma.
Kern, L., Henssen, A., Eggert, A. and Scheer, M.
Cancer Medicine 13
(20): e70348.
October 2024
Detection of minimal residual disease in unselected patients with acute myeloid leukemia using multiparameter flow cytometry for definition of leukemia-associated immunophenotypes and determination of their frequencies in normal bone marrow.
Kern, W., Danhauser-Riedl, S., Ratei, R., Schnittger, S., Schoch, C., Kolb, H.J., Ludwig, W.D., Hiddemann, W. and Haferlach, T.
Haematologica 88
: 646-653.
1 June 2003
Correlation of protein expression and gene expression in acute leukemia.
Kern, W., Kohlmann, A., Wuchter, C., Schnittger, S., Schoch, C., Mergenthaler, S., Ratei, R., Ludwig, W.D., Hiddemann, W. and Haferlach, T.
Cytometry 55B
: 29-36.
1 September 2003
Intrahepatic arterial versus intravenous fluorouracil and folinic acid for colorectal cancer liver metastases: a multicentre randomised trial.
Kerr, D.J., McArdle, C.S., Ledermann, J., Taylor, I., Sherlock, D.J., Schlag, P.M., Buckels, J., Mayer, D., Cain, D. and Stephens, R.J.
Lancet 361
(1): 368-373.
1 February 2003
Profiling of sub-lethal in vitro effects of multi-walled carbon nanotubes reveals changes in chemokines and chemokine receptors.
Keshavan, S., Andón, F.T., Gallud, A., Chen, W., Reinert, K., Tran, L. and Fadeel, B.
Nanomaterials 11
(4): 883.
30 March 2021
Subclone eradication analysis identifies targets for enhanced cancer therapy and reveals L1 retrotransposition as a dynamic source of cancer heterogeneity.
Ketola, K., Kaljunen, H., Taavitsainen, S., Kaarijärvi, R., Järvelä, E., Rodriguez Martin, B., Haase, K., Woodcock, D.J., Tubio, J., Wedge, D.C., Nykter, M. and Bova, G.S.
Cancer Research 81
(19): 4901-4909.
October 2021
Protein S3 fragments neighboring mRNA during elongation and termination of translation on the human ribosome.
Khairulina, Y.S., Molotkov, M.V., Bulygin, K.N., Graifer, D.M., Ven’yaminova, A.G., Frolova, L.Y., Stahl, J. and Karpova, G.G.
Russian Journal of Bioorganic Chemistry 34
(6): 691-697.
November 2008
Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis.
Khajuria, R.K., Munschauer, M., Ulirsch, J.C., Fiorini, C., Ludwig, L.S., McFarland, S.K., Abdulhay, N.J., Specht, H., Keshishian, H., Mani, D.R., Jovanovic, M., Ellis, S.R., Fulco, C.P., Engreitz, J.M., Schütz, S., Lian, J., Gripp, K.W., Weinberg, O.K., Pinkus, G.S., Gehrke, L., Regev, A., Lander, E.S., Gazda, H.T., Lee, W.Y., Panse, V.G., Carr, S.A. and Sankaran, V.G.
Cell 173
(1): 90-103.
22 March 2018
Sequence-specific DNA binding determined by contacts outside the helix-turn-helix motif of the ParB homolog KorB.
Khare, D., Ziegelin, G., Lanka, E. and Heinemann, U.
Nature Structural & Molecular Biology 11
(7): 656-663.
1 January 2004
Crystal structure of native and a mutant of Lampyris turkestanicus luciferase implicate in bioluminescence color shift.
Kheirabadi, M., Sharafian, Z., Naderi-Manesh, H., Heinemann, U., Gohlke, U. and Hosseinkhani, S.
Biochimica et Biophysica Acta - Proteins and Proteomics 1834
(12): 2729-2735.
6 October 2013
Osteopontin is a prognostic circulating biomarker in patients with neuroendocrine neoplasms.
Kidess, E., Giesecke, Y., Eichhorn, I., Mohr, R., Jann, H., Fischer, C., Wiedenmann, B., Roderburg, C., Tacke, F. and Sigal, M.
Journal of Cancer Research and Clinical Oncology 149
(12): 10925-10933.
September 2023
A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer.
Kieback, E., Charo, J., Sommermeyer, D., Blankenstein, T. and Uckert, W.
Proceedings of the National Academy of Sciences of the United States of America 105
(2): 623-628.
15 January 2008
A method for the generation of TCR retrogenic mice.
Kieback, E., Hilgenberg, E. and Fillatreau, S.
Methods in Molecular Biology 1193
: 117-126.
2014
Factors influencing subcellular localization of the human papillomavirus L2 minor structural protein.
Kieback, E. and Mueller, M.
Virology 345
(1): 199-208.
5 February 2006
Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity.
Kieback, E., Hilgenberg, E., Stervbo, U., Lampropoulou, V., Shen, P., Bunse, M., Jaimes, Y., Boudinot, P., Radbruch, A., Klemm, U., Kühl, A.A., Liblau, R., Hoevelmeyer, N., Anderton, S.M., Uckert, W. and Fillatreau, S.
Immunity 44
(5): 1114-1126.
17 May 2016
Intestinal retinol saturase is implicated in the development of obesity and epithelial homeostasis upon injury.
Kiefer, M.F., Meng, Y., Yang, N., Vahrenbrink, M., Wulff, S., Li, C., Wowro, S.J., Petricek, K.M., Sommerfeld, M., Flores, R.E., Obermayer, B., Piepelow, K., Klaus, S., Hartl, K., Guillot, A., Tacke, F., Sigal, M. and Schupp, M.
American Journal of Physiology Endocrinology and Metabolism 327
(2): E203-E216.
August 2024
Characterization and modulation of anti- αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Kierkels, G.J.J., van Diest, E., Hernández-López, P., Scheper, W., de Bruin, A.C.M., Frijlink, E., Aarts-Riemens, T., van Dooremalen, S.F.J., Beringer, D.X., Oostvogels, R., Kramer, L., Straetemans, T., Uckert, W., Sebestyén, Z. and Kuball, J.
Molecular Therapy - Methods and Clinical Development 22
(10): 388-400.
10 September 2021
Establishment of early lymphoid organ infrastructure in transplanted tumors mediated by local production of lymphotoxin alpha and in the combined absence of functional B and T cells.
Kim, H.J., Kammertoens, T., Janke, M., Schmetzer, O., Qin, Z., Berek, C. and Blankenstein, T.
Journal of Immunology 172
(7): 4037-4047.
1 January 2004
Peripheral artery occlusive disease (PAOD) in chronic phase chronic myeloid leukemia patients treated with nilotinib or Imatinib.
Kim, T.D., Rea, D., Schwarz, M., Grille, P., Nicolini, F.E., Rosti, G., Levato, L., Giles, F.J., Dombret, H., Mirault, T., Labussiere, H., Lindhorst, R., Haverkamp, W., Buschmann, I., Doerken, B. and le Coutre, P.D.
Leukemia 27
(6): 1316-1321.
5 April 2013
Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D., Schwarz, M., Nogai, H., Grille, P., Westermann, J., Ploeckinger, U., Braun, D., Schweizer, U., Arnold, R., Doerken, B. and le Coutre, P.
Thyroid 20
(11): 1209-1214.
9 November 2010
Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D., Tuerkmen, S., Schwarz, M., Koca, G., Nogai, H., Bommer, C., Doerken, B., Daniel, P. and le Coutre, P.
Haematologica 95
(4): 582-588.
April 2010
Clinical cardiac safety profile of nilotinib.
Kim, T.D., le Coutre, P., Schwarz, M., Grille, P., Levitin, M., Fateh-Moghadam, S., Giles, F.J., Doerken, B., Haverkamp, W. and Koehncke, C.
Haematologica 97
(6): 883-889.
June 2012
PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity.
Kim, H., Kim, H., Feng, Y., Li, Y., Tamiya, H., Tocci, S. and Ronai, Z.A.
Science Translational Medicine 12
(551): eaaz5683.
8 July 2020
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.
Kim, H., Nguyen, N.P., Turner, K., Wu, S., Gujar, A.D., Luebeck, J., Liu, J., Deshpande, V., Rajkumar, U., Namburi, S., Amin, S.B., Yi, E., Menghi, F., Schulte, J.H., Henssen, A.G., Chang, H.Y., Beck, C.R., Mischel, .S., Bafna, V. and Verhaak, R.G.W.
Nature Genetics 52
(9): 891-897.
September 2020
An RNAi-based approach to down-regulate a gene family in vivo.
Kim, J., Badaloni, A., Willert, T., Zimber-Strobl, U., Kühn, R., Wurst, W. and Kieslinger, M.
PLoS ONE 8
(11): e80312.
12 November 2013
Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M., Wende, H., Walcher, J., Kühnemund, J., Cheret, C., Kempa, S., McShane, E., Selbach, M., Lewin, G.R. and Birchmeier, C.
Genes & Development 32
(9-10): 645-657.
10 May 2018
Graft-versus-host-reactive donor CD4 cells can induce T cell-mediated rejection of the donor marrow in mixed allogeneic chimeras prepared with nonmyeloablative conditioning.
Kim, Y.M., Mapara, M.Y., Down, J.D., Johnson, K.W., Boisgerault, F., Akiyama, Y., Benichou, G., Pelot, M., Zhao, G. and Sykes, M.
Blood 103
: 732-739.
15 January 2004
Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Kirchner, F., Schuetz, A., Boldt, L.H., Martens, K., Dittmar, G., Haverkamp, W., Thierfelder, L., Heinemann, U. and Gerull, B.
Circulation Cardiovascular Genetics 5
(4): 400-411.
1 August 2012
Braveheart, a long noncoding RNA required for cardiovascular lineage commitment.
Klattenhoff, C.A., Scheuermann, J.C., Surface, L.E., Bradley, R.K., Fields, P.A., Steinhauser, M.L., Ding, H., Butty, V.L., Torrey, L., Haas, S., Abo, R., Tabebordbar, M., Lee, R.T., Burge, C.B. and Boyer, L.A.
Cell 152
(3): 570-83.
31 January 2013
Developmental signaling in myocardial progenitor cells: A comprehensive view of Bmp- and Wnt/beta-catenin signaling.
Klaus, A. and Birchmeier, W.
Pediatric Cardiology 30
(5): 609-616.
July 2009
Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Klaus, A., Mueller, M., Schulz, H., Saga, Y., Martin, J.F. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 109
(27): 10921-10926.
3 July 2012
Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.
Klaus, A., Saga, Y., Taketo, M.M., Tzahor, E. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104
(47): 18531-18536.
20 November 2007
Characterization of gamma-aminobutyric acid type A receptor associated protein, a novel tumor suppressor, showing reduced expression in breast cancer.
Klebig, C., Seitz, S., Arnold, W., Deutschmann, N., Pacyna-Gengelbach, M., Scherneck, S. and Petersen, I.
Cancer Research 65
: 394-400.
1 January 2005
Profile of differentially expressed genes after transfer of chromosome 17 into the breast cancer cell line CAl51.
Klebig, C., Seitz, S., Korsching, E., Kristiansen, G., Gustavus, D., Scherneck, S. and Petersen, I.
Genes Chromosomes & Cancer 44
(3): 233-246.
27 July 2005
Identification of brain- and bone-specific breast cancer metastasis genes.
Klein, A., Olendrowitz, C., Schmutzler, R., Hampl, J., Schlag, P.M., Maass, N., Arnold, N., Wessel, R., Ramser, J., Meindl, A., Scherneck, S. and Seitz, S.
Cancer Letters 276
(2): 212-220.
18 April 2009
Comparison of gene expression data from human and mouse breast cancers: identification of a conserved breast tumor gene set.
Klein, A., Wessel, R., Graessmann, M., Juergens, M., Petersen, I., Schmutzler, R., Niederacher, D., Arnold, N., Meindl, A., Scherneck, S., Seitz, S. and Graessmann, A.
International Journal of Cancer 121
(3): 683-688.
1 August 2007
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.
Klein, I.A., Resch, W., Jankovic, M., Oliveira, T., Yamane, A., Nakahashi, H., Di Virgilio, M., Bothmer, A., Nussenzweig, A., Robbiani, D.F., Casellas, R. and Nussenzweig, M.C.
Cell 147
(1): 95-106.
30 September 2011
CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T cell subset.
Kleinewietfeld, M., Puentes, F., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 105
(7): 2877-2886.
1 January 2005
CD49d provides access to 'untouched' human Foxp3+ Treg free of contaminating effector cells.
Kleinewietfeld, M., Starke, M., Mitri, D.D., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 113
(4): 827-836.
22 January 2009
Target validation in mice by constitutive and conditional RNAi.
Kleinhammer, A., Wurst, W. and Kühn, R.
Methods in Molecular Biology 986
: 307-323.
23 January 2013
S1P signalling differentially affects migration of peritoneal B cell populations in vitro and influences the production of intestinal IgA in vivo.
Kleinwort, A., Luehrs, F., Heidecke, C.D., Lipp, M. and Schulze, T.
International Journal of Molecular Sciences 19
(2): 391.
29 January 2018
AML with complex karyotype: extreme genomic complexity revealed by combined long-read sequencing and Hi-C technology.
Klever, M.K., Sträng, E., Hetzel, S., Jungnitsch, J., Dolnik, A., Schöpflin, R., Schrezenmeier, J.F.F., Schick, F., Blau, O., Westermann, J., Rücker, F.G., Xia, Z., Döhner, K., Schrezenmeier, H., Spielmann, M., Meissner, A., Melo, U.S., Mundlos, S. and Bullinger, L.
Blood Advances 7
(21): 6520-6531.
14 November 2023
A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.
Klinghammer, K., Raguse, J.D., Plath, T., Albers, A.E., Joehrens, K., Zakarneh, A., Brzezicha, B., Wulf-Goldenberg, A., Keilholz, U., Hoffmann, J. and Fichtner, I.
International Journal of Cancer 136
(12): 2940-2948.
15 June 2015
Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer.
Klinghammer, K., Politz, O., Eder, T., Otto, R., Raguse, J.D., Albers, A., Kaufmann, A., Tinhofer, I., Hoffmann, J., Keller, U. and Keilholz, U.
Oncotarget 11
(41): 3688-3697.
13 October 2020
Adenine deoxynucleotides fludarabine and cladribine induce apoptosis in a CD95/Fas receptor, FADD and caspase-8-independent manner by activation of the mitochondrial cell death pathway.
Kloepfer, A., Hasenjaeger, A., Belka, C., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 23
: 9408-9418.
1 January 2004
Critical role of PI3K signaling for NF-κB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.
Kloo, B., Nagel, D., Pfeifer, M., Grau, M., Duewel, M., Vincendeau, M., Doerken, B., Lenz, P., Lenz, G. and Krappmann, D.
Proceedings of the National Academy of Sciences of the United States of America 108
(1): 272-277.
4 January 2011
Der Weg zum diagnostischen "Tool" - Entwicklung eines Mikroarrays zur Prognose und Therapie-Praediktion von Darmkrebs [The pathway to diagnostic tool - Development of a microarray for the prognosis and therapy prediction of intestinal cancer].
Kloska, S., Eickhoff, H. and Kemmner, W.
Biospektrum 11
(1): 572-573.
2005
Genauigkeit der sonographischen Milzgewichtsbestimmung am Lebenden im Vergleich zum pathologischen Korrelat [Accuracy of the sonographic determination of the splenic weight in comparison with the weight at autopsy].
Kluehs, L., Teichgraeber, U.K., Schneider, U., Ludwig, W.D., Doerken, B. and Benter, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 175
(4): 532-535.
1 April 2003
Structural investigation of glycan recognition by the ERAD quality control lectin Yos9.
Kniss, A., Kazemi, S., Löhr, F., Berger, M., Rogov, V.V., Güntert, P., Sommer, T., Jarosch, E. and Dötsch, V.
Journal of Biomolecular NMR 72
(1-2): 1-10.
October 2018
Chain assembly and disassembly processes differently affect the conformational space of ubiquitin chains.
Kniss, A., Schuetz, D., Kazemi, S., Pluska, L., Spindler, P.E., Rogov, V.V., Husnjak, K., Dikic, I., Güntert, P., Sommer, T., Prisner, T.F. and Dötsch, V.
Structure 26
(2): 249-258.
6 February 2018
B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice.
Knittel, G., Liedgens, P., Korovkina, D., Seeger, J.M., Al-Baldawi, Y., Al-Maarri, M., Fritz, C., Vlantis, K., Bezhanova, S., Scheel, A.H., Wolz, O.O., Reimann, M., Möller, P., López, C., Schlesner, M., Lohneis, P., Weber, A.N.R., Trümper, L., Staudt, L.M., Ortmann, M., Pasparakis, M., Siebert, R., Schmitt, C.A., Klatt, A.R., Wunderlich, F.T., Schäfer, S.C., Persigehl, T., Montesinos-Rongen, M., Odenthal, M., Büttner, R., Frenzel, L.P., Kashkar, H. and Reinhardt, H.C.
Blood 127
(22): 2732-2741.
2 June 2016
Cytokeratin profiles identify diagnostic signatures in colorectal cancer using multiplex analysis of tissue microarrays.
Knoesel, T., Emde, V., Schluens, K., Schlag, P.M., Dietel, M. and Petersen, I.
Cellular Oncology 28
: 167-175.
2006
Chromosomal alterations during lymphatic and liver metastasis formation of colorectal cancer [Erratum in: Neoplasia. vol 6, pg 686, 2004].
Knoesel, T., Schluens, K., Stein, U., Schwabe, H., Schlag, P.M., Dietel, M. and Petersen, I.
Neoplasia 6
(1): 23-28.
1 January 2004
Genetic imbalances with impact on survival in colorectal cancer patients.
Knoesel, T., Schluens, K., Stein, U., Schwabe, H., Schlag, P.M., Dietel, M. and Petersen, I.
Histopathology 43
(4): 323-331.
October 2003
Identification of drug candidates targeting monocyte reprogramming in people living with HIV.
Knoll, R., Bonaguro, L., Dos Santos, J.C., Warnat-Herresthal, S., Jacobs-Cleophas, M.C.P., Blümel, E., Reusch, N., Horne, A., Herbert, M., Nuesch-Germano, M., Otten, T., van der Heijden, W.A., van de Wijer, L., Shalek, A.K., Händler, K., Becker, M., Beyer, M.D., Netea, M.G., Joosten, L.A.B., van der Ven, A.J.A.M., Schultze, J.L. and Aschenbrenner, A.C.
Frontiers in Immunology 14
: 1275136.
20 November 2023
Interferon-γ receptor signaling in dendritic cells restrains spontaneous proliferation of CD4(+) T cells in chronic lymphopenic mice.
Knop, L., Frommer, C., Stoycheva, D., Deiser, K., Kalinke, U., Blankenstein, T., Kammertoens, T., Dunay, I.R. and Schüler, T.
Frontiers in Immunology 10
: 140.
7 February 2019
Overexpression of cyclooxygenase-2 correlates with chromosomal gain at the cyclooxygenase-2 locus and decreased patient survival in advanced colorectal carcinomas.
Knosel, T., Yu, Y.W., Stein, U., Schwabe, H., Schluns, K., Schlag, P.M., Dietel, M. and Petersen, I.
Diseases of the Colon & Rectum 47
(1): 70-77.
January 2004
Aggressive lymphoma after CD19 CAR T-cell therapy.
Kobbe, G., Brüggemann, M., Baermann, B.N., Wiegand, L., Trautmann, H., Yousefian, S., Libertini, S., Menssen, H.D., Maier, H.J., Ulrich, P., Gao, J., Bruch, P.M., Liebers, N., Radujkovic, A., Seifert, M., Schniederjohann, C., Paramasivam, N., Fitzgerald, D., Seidel, M., Esposito, I., Germing, U., Cadeddu, R.P., Nachtkamp, K., Jäger, P., Ulrych, T., Fischer, J.C., Rox, J.M., Giesel, F., Koch, R., Antoch, G., Distler, J.H.W., Meuth, S.G., Jacobsen, M., Hübschmann, D., Lu, J., Iaccarino, I., Haas, S., Damm, F. and Dietrich, S.
New England Journal of Medicine 391
(13): 1217-1226.
3 October 2024
Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: biphasic heat induction of cytosine deaminase suicide gene expression.
Kobelt, D., Aumann, J., Fichtner, I., Stein, U., Schlag, P.M. and Walther, W.
Molecular Biotechnology 46
(2): 197-205.
October 2010
Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector.
Kobelt, D., Aumann, J., Schmidt, M., Wittig, B., Fichtner, I., Behrens, D., Lemm, M., Freundt, G., Schlag, P.M. and Walther, W.
Molecular Oncology 8
(3): 609-619.
May 2014
Performance of high quality minicircle DNA for in vitro and in vivo gene transfer.
Kobelt, D., Schleef, M., Schmeer, M., Aumann, J., Schlag, P.M. and Walther, W.
Molecular Biotechnology 53
(1): 80-89.
January 2013
A brief introduction to current cancer gene therapy.
Kobelt, D., Pahle, J. and Walther, W.
Methods in Molecular Biology 2521
(3): 1-21.
23 June 2022
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt, D., Perez-Hernandez, D., Fleuter, C., Dahlmann, M., Zincke, F., Smith, J., Migotti, R., Popp, O., Burock, S., Walther, W., Dittmar, G., Mertins, P. and Stein, U.
Oncogene 40
(34): 5286-5301.
26 August 2021
Real-time cell migration monitoring to analyze drug synergism in the scratch assay using the IncuCyte system.
Kobelt, D., Walther, W. and Stein, U.S.
Methods in Molecular Biology 2294
: 133-142.
2021
Pro-inflammatory TNF-α and IFN-γ promote tumor growth and metastasis via induction of MACC1.
Kobelt, D., Zhang, C., Clayton-Lucey, I.A., Glauben, R., Voss, C., Siegmund, B. and Stein, U.
Frontiers in Immunology 11
: 980.
27 May 2020
Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma.
Kocak, H., Ackermann, S., Hero, B., Kahlert, Y., Oberthuer, A., Juraeva, D., Roels, F., Theissen, J., Westermann, F., Deubzer, H., Ehemann, V., Brors, B., Odenthal, M., Berthold, F. and Fischer, M.
Cell Death & Disease 4
: e586.
11 April 2013
Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas.
Koch, A., Hrychyk, A., Hartmann, W., Waha, A., Mikeska, T., Waha, A., Schueller, U., Soerensen, N., Berthold, F., Goodyer, C.G., Wiestler, O.D., Birchmeier, W., Behrens, J. and Pietsch, T.
International Journal of Cancer 121
(2): 284-291.
15 July 2007
Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas.
Koch, A., Weber, N., Waha, A., Hartmann, W., Denkhaus, D., Behrens, J., Birchmeier, W., von Schweinitz, D. and Pietsch, T.
Journal of Pathology 204
(5): 546-554.
1 January 2004
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Koche, R.P., Rodriguez-Fos, E., Helmsauer, K., Burkert, M., MacArthur, I.C., Maag, J., Chamorro, R., Munoz-Perez, N., Puiggròs, M., Dorado Garcia, H., Bei, Y., Röefzaad, C., Bardinet, V., Szymansky, A., Winkler, A., Thole, T., Timme, N., Kasack, K., Fuchs, S., Klironomos, F., Thiessen, N., Blanc, E., Schmelz, K., Künkele, A., Hundsdörfer, P., Rosswog, C., Theissen, J., Beule, D., Deubzer, H., Sauer, S., Toedling, J., Fischer, M., Hertwig, F., Schwarz, R.F., Eggert, A., Torrents, D., Schulte, J.H. and Henssen, A.G.
Nature Genetics 52
(1): 29-34.
January 2020
High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
Koechert, K., Ullrich, K., Kreher, S., Aster, J.C., Kitagawa, M., Joehrens, K., Anagnostopoulos, I., Jundt, F., Lamprecht, B., Zimber-Strobl, U., Stein, H., Janz, M., Doerken, B. and Mathas, S.
Oncogene 30
(15): 1831-1840.
14 April 2011
Effective biomodulation by leucovorin of high-dose infusion fluorouracil given as a weekly 24-hour infusion: results of a randomized trial in patients with advanced colorectal cancer.
Koehne, C.H., Schoeffski, P., Wilke, H., Kaeufer, C., Andreesen, R., Ohl, U., Klaasen, U., Westerhausen, M., Hiddemann, W., Schott, G., Harstick, A., Bade, J., Horster, A., Schubert, U., Hecker, H., Doerken, B. and Schmoll, H.J.
Journal of Clinical Oncology 16
(2): 418-426.
February 1998
Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study.
Koelzer, V.H., Herrmann, P., Zlobec, I., Karamitopoulou, E., Lugli, A. and Stein, U.
BMC Cancer 15
(1): 160.
21 March 2015
Crystal structure of KorA bound to operator DNA: insight into repressor cooperation in RP4 gene regulation.
Koenig, B., Mueller, J.J., Lanka, E. and Heinemann, U.
Nucleic Acids Research 37
(6): 1915-1924.
April 2009
The ITS2 Database III-sequences and structures for phylogeny.
Koetschan, C., Foerster, F., Keller, A., Schleicher, T., Ruderisch, B., Schwarz, R., Mueller, T., Wolf, M. and Schultz, J.
Nucleic Acids Research 38
(Suppl 1): D275-D279.
January 2010
Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.
Kofla, G., Radecke, C., Frentsch, M., Walther, W., Stintzing, S., Riess, H., Bullinger, L. and Na, I.K.
OncoImmunology 11
(1): 2068109.
25 April 2022
Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R., Janz, M., Mapara, M.Y., Lemke, B., Stirling, D., Doerken, B., Zenke, M. and Lentzsch, S.
Blood 105
(10): 3833-3840.
1 January 2005
Membrane switch hypothesis. 1. Cell density influences lateral domain structure of tumor cell membranes.
Koklic, T., Pirs, M., Zeisig, R., Abramovic, Z. and Sentjurc, M.
Journal of Chemical Information and Modeling 45
(6): 1701-1707.
28 November 2005
Interaction of alkylphospholipid liposomes with MT-3 breast-cancer cells depends critically on cholesterol concentration.
Koklic, T., Zeisig, R. and Sentjurc, M.
Biochimica et Biophysica Acta - Biomembranes 1778
(12): 2682-2689.
December 2008
Synthetic lethality by PARP inhibitors: new mechanism uncovered based on unresolved transcription-replication conflicts.
Kolesnichenko, M. and Scheidereit, C.
Signal Transduction and Targeted Therapy 9
(1): 179.
29 July 2024
Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M., Mikuda, N., Höpken, U.E., Kärgel, E., Uyar, B., Tufan, A.B., Milanovic, M., Sun, W., Krahn, I., Schleich, K., von Hoff, L., Hinz, M., Willenbrock, M., Jungmann, S., Akalin, A., Lee, S., Schmidt-Ullrich, R., Schmitt, C.A. and Scheidereit, C.
EMBO Journal 40
(6): e104296.
15 March 2021
FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E., Ofenbauer, A., Bulut, S.I., Uyar, B., Baytek, G., Sommermeier, A., Seelk, S., He, M., Hirsekorn, A., Vucicevic, D., Akalin, A., Diecke, S., Lacadie, S.A. and Tursun, B.
Developmental Cell 46
(5): 611-626.
10 September 2018
Resolving crosstalk between signaling pathways using mathematical modeling and time-resolved single cell data.
Konrath, F., Loewer, A. and Wolf, J.
Methods in Molecular Biology 2634
: 267-284.
2023
A systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics.
Konrath, F., Mittermeier, A., Cristiano, E., Wolf, J. and Loewer, A.
PLoS Computational Biology 16
(6): e1007901.
26 June 2020
A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1.
Konrath, F., Willenbrock, M., Busse, D., Scheidereit, C. and Wolf, J.
iScience 26
(10): 107917.
20 October 2023
Simultaneous dimensionality reduction and integration for single-cell ATAC-seq data using deep learning.
Kopp, W., Akalin, A. and Ohler, U.
Nature Machine Intelligence 4
(2): 162-168.
February 2022
Deep learning for genomics using Janggu.
Kopp, W., Monti, R., Tamburrini, A., Ohler, U. and Akalin, A.
Nature Communications 11
(1): 3488.
13 July 2020
Deletion of polycomb repressive complex 2 from mouse intestine causes loss of stem cells.
Koppens, M.A.J., Bounova, G., Gargiulo, G., Tanger, E., Janssen, H., Cornelissen-Steijger, P., Blom, M., Song, J.Y., Wessels, L.F.A. and van Lohuizen, M.
Gastroenterology 151
(4): 684-697.
October 2016
Interpreting deep neural networks for the prediction of translation rates.
Korbel, F., Eroshok, E. and Ohler, U.
BMC Genomics 25
(1): 1061.
9 November 2024
Unlocking the secrets of structural variants in a healthy tissue.
Korbel, J.O. and Sanders, A.D.
Nature Genetics 56
(6): 1047-1048.
June 2024
Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells.
Kordes, U., Krappmann, D., Heissmeyer, V., Ludwig, W.D. and Scheidereit, C.
Leukemia 14
(3): 399-402.
March 2000
EASIX and severe endothelial complications after CD19-directed CAR-T Cell therapy-a cohort study.
Korell, F., Penack, O., Mattie, M., Schreck, N., Benner, A., Krzykalla, J., Wang, Z., Schmitt, M., Bullinger, L., Müller-Tidow, C., Dreger, P. and Luft, T.
Frontiers in Immunology 13
: 877477.
8 April 2022
Phase II trial of temsirolimus for relapsed/refractory primary CNS lymphoma.
Korfel, A., Schlegel, U., Herrlinger, U., Dreyling, M., Schmidt, C., von Baumgarten, L., Pezzutto, A., Grobosch, T., Kebir, S., Thiel, E., Martus, P. and Kiewe, P.
Journal of Clinical Oncology 34
(15): 1757-1763.
20 May 2016
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis.
Kortüm, B., Radhakrishnan, H., Zincke, F., Sachse, C., Burock, S., Keilholz, U., Dahlmann, M., Walther, W., Dittmar, G., Kobelt, D. and Stein, U.
Oncogene 41
(39): 4446-4458.
23 September 2022
Targeted sequencing using a 47 gene multiple myeloma mutation panel (M(3) P) in -17p high risk disease.
Kortüm, K.M., Langer, C., Monge, J., Bruins, L., Egan, J.B., Zhu, Y.X., Shi, C.X., Jedlowski, P., Schmidt, J., Ojha, J., Bullinger, L., Liebisch, P., Kull, M., Champion, M.D., Van Wier, S., Ahmann, G., Rasche, L., Knop, S., Fonseca, R., Einsele, H., Stewart, A.K. and Braggio, E.
British Journal of Haematology 168
(4): 507-510.
February 2015
Longitudinal analysis of 25 sequential sample-pairs using a custom multiple myeloma mutation sequencing panel (M(3)P).
Kortüm, K.M., Langer, C., Monge, J., Bruins, L., Zhu, Y.X., Shi, C.X., Jedlowski, P., Egan, J.B., Ojha, J., Bullinger, L., Kull, M., Ahmann, G., Rasche, L., Knop, S., Fonseca, R., Einsele, H., Stewart, A.K. and Braggio, E.
Annals of Hematology 94
(7): 1205-1211.
July 2015
Role of transcription factors C/EBPalpha and PU.1 in normal hematopoiesis and leukemia.
Koschmieder, S., Rosenbauer, F., Steidl, U., Owens, B.M. and Tenen, D.G.
International Journal of Hematology 81
: 368-377.
1 June 2005
Deletion in the Y chromosome of B10.BR-Y(del) mice alters transcription from MSYq genes and has moderate effect on DNA methylation.
Kotarska, K., Doniec, A., Korostyński, M., Piechota, M., Gołas, A., Lisowski, P. and Styrna, J.
Reproductive Biology 22
(2): 100614.
June 2022
Structure of the dodecameric Yersinia enterocolitica secretin YscC and its trypsin-resistant core.
Kowal, J., Chami, M., Ringler, P., Müller, S.A., Kudryashev, M., Castaño-Díez, D., Amstutz, M., Cornelis, G.R., Stahlberg, H. and Engel, A.
Structure 21
(12): 2152-2161.
3 December 2013
Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.
Kowenz-Leutz, E., Pless, O., Dittmar, G., Knoblich, M. and Leutz, A.
EMBO Journal 29
(6): 1105-1115.
17 March 2010
Novel mechanism of C/EBPbeta (NF-M) transcriptional control: activation through derepression.
Kowenz-Leutz, E., Twamley, G., Ansieau, S. and Leutz, A.
Genes & Development 8
(22): 2781-2791.
15 November 1994
Functional interaction of CCAAT/enhancer-binding-protein-α basic region mutants with E2F transcription factors and DNA.
Kowenz-Leutz, E., Schuetz, A., Liu, Q., Knoblich, M., Heinemann, U. and Leutz, A.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1859
(7): 841-847.
July 2016
An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex.
Kracker, S., Di Virgilio, M., Schwartzentruber, J., Cuenin, C., Forveille, M., Deau, M.C., McBride, K.M., Majewski, J., Gazumyan, A., Seneviratne, S., Grimbacher, B., Kutukculer, N., Herceg, Z., Cavazzana, M., Jabado, N., Nussenzweig, M.C., Fischer, A. and Durandy, A.
Journal of Allergy and Clinical Immunology 135
(4): 998-1007.
April 2015
Deletions, inversions, duplications: engineering of structural variants using CRISPR/Cas in mice.
Kraft, K., Geuer, S., Will, A.J., Chan, W.L., Paliou, C., Borschiwer, M., Harabula, I., Wittler, L., Franke, M., Ibrahim, D.M., Kragesteen, B.K., Spielmann, M., Mundlos, S., Lupiáñez, D.G. and Andrey, G.
Cell Reports 10
(5): 833-839.
10 February 2015
Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis.
Kragesteen, B.K., Spielmann, M., Paliou, C., Heinrich, V., Schöpflin, R., Esposito, A., Annunziatella, C., Bianco, S., Chiariello, A.M., Jerković, I., Harabula, I., Guckelberger, P., Pechstein, M., Wittler, L., Chan, Wi.L., Franke, M., Lupiáñez, D.G., Kraft, K., Timmermann, B., Vingron, M., Visel, A., Nicodemi, M., Mundlos, S. and Andrey, G.
Nature Genetics 50
(10): 1463-1473.
October 2018
Evaluation of combination therapy schedules of doxorubicin and an acid-sensitive albumin-binding prodrug of doxorubicin in the MIA PaCa-2 pancreatic xenograft model.
Kratz, F., Azab, S., Zeisig, R., Fichtner, I. and Warnecke, A.
International Journal of Pharmaceutics 441
(1-2): 499-506.
30 January 2013
Combination therapy with the albumin-binding prodrug of doxorubicin (INNO-206) and doxorubicin achieves complete remissions and improves tolerability in an ovarian A2780 xenograft model.
Kratz, F., Fichtner, I. and Graeser, R.
Investigational New Drugs 30
(4): 1743-1749.
August 2012
Development of albumin-binding doxorubicin prodrugs that are cleaved by prostate-specific antigen.
Kratz, F., Mansour, A., Soltau, J., Warnecke, A., Fichtner, I., Unger, C. and Drevs, J.
Archiv der Pharmazie 338
: 462-472.
7 October 2005
Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas.
Kratzsch, T., Kuhn, S.A., Joedicke, A., Hanisch, U.K., Vajkoczy, P., Hoffmann, J. and Fichtner, I.
Journal of Cancer Research and Clinical Oncology 144
(5): 809-819.
May 2018
Reduced splenic uptake on (68)Ga-Pentixafor-PET/CT imaging in multiple myeloma - a potential imaging biomarker for disease prognosis.
Kraus, S., Klassen, P., Kircher, M., Dierks, A., Habringer, S., Gäble, A., Kortüm, K.M., Weinhold, N., Ademaj-Kospiri, V., Werner, R.A., Schirbel, A., Buck, A.K., Herhaus, P., Wester, H.J., Rosenwald, A., Weber, W.A., Einsele, H., Keller, U., Rasche, L. and Lapa, C.
Theranostics 12
(13): 5986-5994.
8 August 2022
MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.
Krause, C.J., Popp, O., Thirunarayanan, N., Dittmar, G., Lipp, M. and Mueller, G.
Oncotarget 7
(9): 10414-10432.
1 March 2016
A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse.
Krause, F., Mohebian, K., Delpero, M., Hesse, D., Kuehn, R., Arends, D. and Brockmann, G.A.
Mammalian Genome 33
(3): 465–470.
September 2022
Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L., Krupp, F., Harnett, D., Turko, P., Ambrozkiewicz, M.C., Sprink, T., Imami, K., Günnigmann, M., Zinnall, U., Vieira-Vieira, C.H., Schaub, T., Münster-Wandowski, A., Bürger, J., Borisova, E., Yamamoto, H., Rasin, M.R., Ohler, U., Beule, D., Mielke, T., Tarabykin, V., Landthaler, M., Kramer, G., Vida, I., Selbach, M. and Spahn, C.M.T.
Molecular Cell 81
(2): 304-322.
21 January 2021
The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops.
Krauss, N., Wessner, H., Welfle, K., Welfle, H., Scholz, C., Seifert, M., Zubow, K., Ay, J., Hahn, M., Scheerer, P., Skerra, A. and Hoehne, W.
Proteins: Structure, Function, and Bioinformatics 73
(3): 552-565.
15 November 2008
KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.
Kravtsova-Ivantsiv, Y., Shomer, I., Cohen-Kaplan, V., Snijder, B., Superti-Furga, G., Gonen, H., Sommer, T., Ziv, T., Admon, A., Naroditsky, I., Jbara, M., Brik, A., Pikarsky, E., Kwon, Y.T., Doweck, I. and Ciechanover, A.
Cell 161
(2): 333-347.
9 April 2015
The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore.
Kravtsova-Ivantsiv, Y., Sommer, T. and Ciechanover, A.
Angewandte Chemie International Edition 52
(1): 192-198.
2 January 2013
Molecular architecture of synaptic vesicles.
Kravčenko, U., Ruwolt, M., Kroll, J., Yushkevich, A., Zenkner, M., Ruta, J., Lotfy, R., Wanker, E.E., Rosenmund, C., Liu, F. and Kudryashev, M.
Proceedings of the National Academy of Sciences of the United States of America 121
(49): e2407375121.
3 December 2024
T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelop proteins control virus replication in mice.
Krebs, K., Böttinger, N., Huang, L.R., Chmielewski, M., Arzberger, S., Gasteiger, G., Jäger, C., Schmitt, E., Bohne, F., Aichler, M., Uckert, W., Abken, H., Heikenwalder, M., Knolle, P. and Protzer, U.
Gastroenterology 145
(2): 456-465.
August 2013
R-split-CHOP chemotherapy for elderly patients with diffuse large B-cell lymphoma.
Kreher, S., Lammer, F., Augustin, D., Pezzutto, A. and Baldus, C.D.
European Journal of Haematology 93
(1): 70-76.
July 2014
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S., Bouhlel, M.A., Cauchy, P., Lamprecht, B., Li, S., Grau, M., Hummel, F., Köchert, K., Anagnostopoulos, I., Jöhrens, K., Hummel, M., Hiscott, J., Wenzel, S.S., Lenz, P., Schneider, M., Küppers, R., Scheidereit, C., Giefing, M., Siebert, R., Rajewsky, K., Lenz, G., Cockerill, P.N., Janz, M., Dörken, B., Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111
(42): E4513-E4522.
21 October 2014
PET-guided eBEACOPP treatment of advanced-stage Hodgkin lymphoma (HD18): follow-up analysis of an international, open-label, randomised, phase 3 trial.
Kreissl, S., Goergen, H., Buehnen, I., Kobe, C., Moccia, A., Greil, R., Eichenauer, D.A., Zijlstra, J.M., Markova, J., Meissner, J., Feuring-Buske, M., Soekler, M., Beck, H.J., Willenbacher, W., Ludwig, W.D., Pabst, T., Topp, M.S., Hitz, F., Bentz, M., Keller, U.B., Kühnhardt, D., Ostermann, H., Hertenstein, B., Aulitzky, W., Maschmeyer, G., Vieler, T., Eich, H., Baues, C., Stein, H., Fuchs, M., Diehl, V., Dietlein, M., Engert, A. and Borchmann, P.
Lancet Haematology 8
(6): e398-e409.
June 2021
Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes.
Kreslavsky, T., Kim, H.J., Koralov, S.B., Ghitza, D., Buch, T., Cantor, H., Rajewsky, K. and von Boehmer, H.
Journal of Experimental Medicine 210
(10): 1911-1918.
23 September 2013
Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.
Kretschmann, S., Herda, S., Bruns, H., Russ, J., van der Meijden, E.D., Schlötzer-Schrehardt, U., Griffioen, M., Na, I.K., Mackensen, A. and Kremer, A.N.
Journal of Clinical Investigation 129
(7): 2952-2963.
1 July 2019
Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas.
Kretschmer, C., Conradi, A., Kemmner, W. and Sterner-Kock, A.
Cellular Oncology 34
(5): 419-434.
6 October 2011
Identification of early molecular markers for breast cancer.
Kretschmer, C., Sterner-Kock, A., Siedentopf, F., Schoenegg, W., Schlag, P.M. and Kemmner, W.
Molecular Cancer 10
(1): 15.
11 February 2011
Welchen Stellenwert hat die neoadjuvante und die adjuvante Therapie im Behandlungskonzept des Magenkarzinoms? [Efficacy of current adjuvant and neoadjuvant therapeutic concepts in gastric cancer?].
Kretzschmar, A. and Schlag, P.M.
Zentralblatt fuer Chirurgie 131
: 121-125.
13 April 2006
Weekly 24-Hour infusion of high-dose 5-fluorouracil plus folinic acid in combination with mitomycin C for the treatment of advanced gastric cancer.
Kretzschmar, A., Reichardt, P., Thuss-Patience, P.C., Hohenberger, P., Benter, T., Doerken, B. and Koehne, C.H.
Oncology 59
(1): 14-17.
June 2000
Filgrastim-induced stem cell mobilization in chronic myeloid leukaemia patients during imatinib therapy: safety, feasibility and evidence for an efficient in vivo purging.
Kreuzer, K.A., Kluehs, C., Baskaynak, G., Movassaghi, K., Doerken, B. and Le Coutre, P.
British Journal of Haematology 124
(2): 195-199.
1 January 2004
Preexistence and evolution of imatinib mesylate-resistant clones in chronic myelogenous leukemia detected by a PNA-based PCR clamping technique.
Kreuzer, K.A., Le Coutre, P., Landt, O., Na, I.K., Schwarz, M., Schultheis, K., Hochhaus, A. and Doerken, B.
Annals of Hematology 82
(5): 284-289.
May 2003
Fluorescent 5'-exonuclease assay for the absolute quantification of Wilms' tumour gene (WT1) mRNA: implications for monitoring human leukaemias.
Kreuzer, K.A., Saborowski, A., Lupberger, J., Appelt, C., Na, I.K., le Coutre, P. and Schmidt, C.A.
British Journal of Haematology 114
(2): 313-318.
August 2001
Synchrones Auftreten eines Adenokarzinoms und eines Non-Hodgkin B-Zell-Lymphoms bei einem Patienten mit einem variablen Immundefektsyndrom (CVID) [When malignancy hits twice - synchronous gastric carcinoma and non-Hodgkin-B-cell lymphoma in a patient with common variable immunodeficiency].
Krick, D., Hauptmann, K., Penndorf, V., Tacke, F., Krüger, R., von Bernuth, H. and Sigal, M.
Zeitschrift fur Gastroenterologie 61
(7): 827-831.
July 2023
The prognostic impact of CD163-positive macrophages in follicular lymphoma: a study from the BC Cancer Agency and the Lymphoma Study Association.
Kridel, R., Xerri, L., Gelas-Dore, B., Tan, K., Feugier, P., Vawda, A., Canioni, D., Farinha, P., Boussetta, S., Moccia, A.A., Brice, P., Chavez, E.A., Kyle, A.H., Scott, D.W., Sanders, A.D., Fabiani, B., Slack, G.W., Minchinton, A.I., Haioun, C., Connors, J.M., Sehn, L.H., Steidl, C., Gascoyne, R.D. and Salles, G.
Clinical Cancer Research 21
(15): 3428-3435.
August 2015
NF-κB participates in mouse hair cycle control and plays distinct roles in the various pelage hair follicle types.
Krieger, K., Millar, S.E., Mikuda, N., Krahn, I., Kloepper, J.E., Bertolini, M., Scheidereit, C., Paus, R. and Schmidt-Ullrich, R.
Journal of Investigative Dermatology 138
(2): 256-264.
February 2018
Caspase-dependent regulation and subcellular redistribution of the transcriptional modulator YY1 during apoptosis.
Krippner-Heidenreich, A., Walsemann, G., Beyrouthy, M.J., Speckgens, S., Kraft, R., Thole, H., Talanian, R.V., Hurt, M.M. and Luescher, B.
Molecular and Cellular Biology 25
(9): 3704-3714.
May 2005
Cell of origin determines clinically relevant subtypes of MLL-rearranged AML.
Krivtsov, A.V., Figueroa, M.E., Sinha, A.U., Stubbs, M.C., Feng, Z., Valk, P.J.M., Delwel, R., Döhner, K., Bullinger, L., Kung, A.L., Melnick, A.M. and Armstrong, S.A.
Leukemia 27
(4): 852-60.
April 2013
Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G., Uhlemann, R., Richter, N., Klempin, F., Wegner, S., Staerck, L., Wolf, S., Uckert, W., Kettenmann, H., Endres, M. and Gertz, K.
Acta Neuropathologica 135
(4): 551.
April 2018
Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Kroschinsky, F., Middeke, J.M., Janz, M., Lenz, G., Witzens-Harig, M., Bouabdallah, R., La Rosée, P., Viardot, A., Salles, G., Kim, S.J., Kim, T.M., Ottmann, O., Chromik, J., Quinson, A.M., von Wangenheim, U., Burkard, U., Berk, A. and Schmitz, N.
Investigational New Drugs 38
(5): 1472-1482.
October 2020
Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.
Kruschinski, A., Moosmann, A., Poschke, I., Norell, H., Chmielewski, M., Seliger, B., Kiessling, R., Blankenstein, T., Abken, H. and Charo, J.
Proceedings of the National Academy of Sciences of the United States of America 105
(45): 17481-17486.
11 November 2008
Neutropenic sepsis in the ICU: Outcome predictors in a two-phase model and microbiology findings.
Kruse, J.M., Jenning, T., Rademacher, S., Arnold, R., Schmitt, C.A., Jörres, A., Enghard, P. and Oppert, M.
Critical Care Research and Practice 2016
: 8137850.
2016
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Kruse, T., Benz, C., Garvanska, D.H., Lindqvist, R., Mihalic, F., Coscia, F., Inturi, R., Sayadi, A., Simonetti, L., Nilsson, E., Ali, M., Kliche, J., Moliner Morro, A., Mund, A., Andersson, E., McInerney, G., Mann, M., Jemth, P., Davey, N.E., Överby, A.K., Nilsson, J. and Ivarsson, Y.
Nature Communications 12
(1): 6761.
19 November 2021
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Krämer, B., Knoll, R., Bonaguro, L., ToVinh, M., Raabe, J., Astaburuaga-García, R., Schulte-Schrepping, J., Kaiser, K.M., Rieke, G.J., Bischoff, J., Monin, M.B., Hoffmeister, C., Schlabe, S., De Domenico, E., Reusch, N., Händler, K., Reynolds, G., Blüthgen, N., Hack, G., Finnemann, C., Nischalke, H.D., Strassburg, C.P., Stephenson, E., Su, Y., Gardner, L., Yuan, D., Chen, D., Goldman, J., Rosenstiel, P., Schmidt, S.V., Latz, E., Hrusovsky, K., Ball, A.J., Johnson, J.M., Koenig, P.A., Schmidt, F.I., Haniffa, M., Heath, J.R., Kümmerer, B.M., Keitel, V., Jensen, B., Stubbemann, P., Kurth, F., Sander, L.E., Sawitzki, B., Aschenbrenner, A.C., Schultze, J.L. and Nattermann, J.
Immunity 54
(11): 2650-2669.
9 November 2021
Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia.
Krönke, J., Bullinger, L., Teleanu, V., Tschürtz, F., Gaidzik, V.I., Kühn, M.W.M., Rücker, F.G., Holzmann, K., Paschka, P., Kapp-Schwörer, S., Späth, D., Kindler, T., Schittenhelm, M., Krauter, J., Ganser, A., Göhring, G., Schlegelberger, B., Schlenk, R.F., Döhner, H. and Döhner, K.
Blood 122
(1): 100-108.
4 July 2013
IKZF1 expression is a prognostic marker in newly diagnosed standard-risk multiple myeloma treated with lenalidomide and intensive chemotherapy: a study of the German Myeloma Study Group (DSMM).
Krönke, J., Kuchenbauer, F., Kull, M., Teleanu, V., Bullinger, L., Bunjes, D., Greiner, A., Kolmus, S., Köpff, S., Schreder, M., Mügge, L.O., Straka, C., Engelhardt, M., Döhner, H., Einsele, H., Bassermann, F., Bargou, R., Knop, S. and Langer, C.
Leukemia 31
(6): 1363-1367.
June 2017
In vitro testing of drug response in primary multiple myeloma cells using a microwell-based technology.
Krüger, J., Blau, I.W., Blau, O., Bettelli, A., Rocchi, L., Bocchi, M., Krönke, J., Bullinger, L., Keller, U. and Nogai, A.
Leukemia Research 147
: 107599.
December 2024
Regulation of microRNA expression and abundance during lymphopoiesis.
Kuchen, S., Resch, W., Yamane, A., Kuo, N., Li, Z., Chakraborty, T., Wei, L., Laurence, A., Yasuda, T., Peng, S., Hu-Li, J., Lu, K., Dubois, W., Kitamura, Y., Charles, N., Sun, H.W., Muljo, S., Schwartzberg, P.L., Paul, W.E., O'Shea, J., Rajewsky, K. and Casellas, R.
Immunity 32
(6): 828-839.
25 June 2010
The big chill: growth of in situ structural biology with cryo-electron tomography.
Kudryashev, M.
QRB Discovery 5
: e10.
13 December 2024
The ultrastructure of Chlorobaculum tepidum revealed by cryo-electron tomography.
Kudryashev, M., Aktoudianaki, A., Dedoglou, D., Stahlberg, H. and Tsiotis, G.
Biochimica et Biophysica Acta - Bioenergetics 1837
(10): 1635-1642.
October 2014
The structure of the mouse serotonin 5-HT3 receptor in lipid vesicles.
Kudryashev, M., Castaño-Díez, D., Deluz, C., Hassaine, G., Grasso, L., Graf-Meyer, A., Vogel, H. and Stahlberg, H.
Structure 24
(1): 165-170.
5 January 2016
Evidence of direct cell-cell fusion in Borrelia by cryogenic electron tomography.
Kudryashev, M., Cyrklaff, M., Alex, B., Lemgruber, L., Baumeister, W., Wallich, R. and Frischknecht, F.
Cellular Microbiology 13
(5): 731-741.
May 2011
Comparative cryo-electron tomography of pathogenic Lyme disease spirochetes.
Kudryashev, M., Cyrklaff, M., Baumeister, W., Simon, M.M., Wallich, R. and Frischknecht, F.
Molecular Microbiology 71
(6): 1415-1434.
March 2009
Distinct in situ structures of the Borrelia flagellar motor.
Kudryashev, M., Cyrklaff, M., Wallich, R., Baumeister, W. and Frischknecht, F.
Journal of Structural Biology 169
(1): 54-61.
January 2010
Yersinia enterocolitica type III secretion injectisomes form regularly spaced clusters, which incorporate new machines upon activation.
Kudryashev, M., Diepold, A., Amstutz, M., Armitage, J.P., Stahlberg, H. and Cornelis, G.R.
Molecular Microbiology 95
(5): 875-884.
March 2015
Geometric constrains for detecting short actin filaments by cryogenic electron tomography.
Kudryashev, M., Lepper, S., Baumeister, W., Cyrklaff, M. and Frischknecht, F.
PMC Biophysics 3
(1): 6.
5 March 2010
Positioning of large organelles by a membrane-associated cytoskeleton in Plasmodium sporozoites.
Kudryashev, M., Lepper, Simone, Stanway, Rebecca, Bohn, Stefan, Baumeister, Wolfgang, Cyrklaff, Marek and Frischknecht, Friedrich
Cellular Microbiology 12
(3): 362-371.
March 2010
Meeting report: Breaking barriers in microscopy.
Kudryashev, M. and Münter, S.
Biotechnology Journal 2
(1): 30-32.
January 2007
Structural basis for chirality and directional motility of Plasmodium sporozoites.
Kudryashev, M., Münter, S., Lemgruber, L., Montagna, G., Stahlberg, H., Matuschewski, K., Meissner, M., Cyrklaff, M. and Frischknecht, F.
Cellular Microbiology 14
(11): 1757-1768.
November 2012
Assessing the benefits of focal pair cryo-electron tomography.
Kudryashev, M., Stahlberg, H. and Castaño-Díez, D.
Journal of Structural Biology 178
(2): 88-97.
May 2012
In situ structural analysis of the Yersinia enterocolitica injectisome.
Kudryashev, M., Stenta, M., Schmelz, S., Amstutz, M., Wiesand, U., Castaño-Díez, D., Degiacomi, M.T., Münnich, S., Bleck, C.K., Kowal, J., Diepold, A., Heinz, D.W., Dal Peraro, M., Cornelis, G.R. and Stahlberg, H.
eLife 2
: e00792.
30 July 2013
Structure of the type VI secretion system contractile sheath.
Kudryashev, M., Wang, R.Y.R., Brackmann, M., Scherer, S., Maier, T., Baker, D., DiMaio, F., Stahlberg, H., Egelman, E.H. and Basler, M.
Cell 160
(5): 952-962.
26 February 2015
Modelling phagosomal lipid networks that regulate actin assembly.
Kuehnel, M., Mayorga, L.S., Dandekar, T., Thakar, J., Schwarz, R., Anes, E., Griffiths, G. and Reich, J.
BMC Systems Biology 2
(1): 107.
5 December 2008
Long-term lanreotide treatment in six patients with congenital hyperinsulinism.
Kuehnen, P., Marquard, J., Ernert, A., Meissner, T., Raile, K., Wannenmacher, G. and Blankenstein, O.
Hormone Research in Paediatrics 78
(2): 106-112.
September 2012
Occurrence of giant focal forms of congenital hyperinsulinism with incorrect visualization by (18)F DOPA-PET/CT scanning.
Kuehnen, P., Matthae, R., Arya, V., Hauptmann, K., Rothe, K., Waechter, S., Singer, M., Mohnike, W., Eberhard, T., Raile, K., Lauffer, L.M., Iakoubov, R., Hussain, K. and Blankenstein, O.
Clinical Endocrinology 81
(6): 847-854.
December 2014
Identification of an ovine atadenovirus gene whose product activates the viral E2 promoter: possible involvement of E2F-1.
Kuemin, D., Hofmann, C., Uckert, W., Both, G.W. and Loeser, P.
Virology 318
(1): 79-89.
5 January 2004
Unique self-palmitoylation activity of the transport protein particle component Bet3: A mechanism required for protein stability.
Kuemmel, D., Heinemann, U. and Veit, M.
Proceedings of the National Academy of Sciences of the United States of America 103
(34): 12701-12706.
22 August 2006
Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2.
Kuemmel, D., Mueller, J.J., Roske, Y., Henke, N. and Heinemann, U.
Journal of Molecular Biology 361
(1): 22-32.
4 August 2006
The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex.
Kuemmel, D., Mueller, J.J., Roske, Y., Misselwitz, R., Buessow, K. and Heinemann, U.
EMBO Reports 6
(8): 787-793.
6 August 2005
Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells.
Kuemmel, D., Oeckinghaus, A., Wang, C., Krappmann, D. and Heinemann, U.
FEBS Letters 582
(27): 3729-3733.
12 November 2008
Structural studies of the human tethering complex TRAPP involved in vesicular transport.
Kuemmel, D., Turnbull, A.P., Mueller, J.J., Roske, Y. and Heinemann, U.
2006
Characterization of the self-palmitoylation activity of the transport protein particle component Bet3.
Kuemmel, D., Walter, J., Heck, M., Heinemann, U. and Veit, M.
Cellular and Molecular Life Sciences 67
(15): 2653-2664.
August 2010
Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells.
Kuerbitz, C., Heise, D., Redmer, T., Goumas, F., Arlt, A., Lemke, J., Rimbach, G., Kalthoff, H. and Trauzold, A.
Cancer Science 102
(4): 728-734.
April 2011
Sequence Bundles: a novel method for visualising, discovering and exploring sequence motifs.
Kultys, M., Nicholas, L., Schwarz, R., Goldman, N. and King, J.
BMC Proceedings 8
(Suppl 2): S8.
28 August 2014
Purification and preliminary X-ray crystallographic studies of beta-microseminoprotein from human seminal plasma.
Kumar, V., Roske, Y., Singh, N., Heinemann, U., Singh, T.P. and Yadav, S.
Acta Crystallographica Section F 65
(5): 518-521.
1 May 2009
Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
Kumpf, O., Giamarellos-Bourboulis, E.J., Koch, A., Hamann, L., Mouktaroudi, M., Oh, D.Y., Latz, E., Lorenz, E., Schwartz, D.A., Ferwerda, B., Routsi, C., Skalioti, C., Kullberg, B.J., van der Meer, J.W., Schlag, P.M., Netea, M.G., Zacharowski, K. and Schumann, R.R.
Critical Care 14
(3): R103.
3 June 2010
Pre- and postoperative cytokine release after in vitro whole blood lipopolysaccharide stimulation and frequent toll-like receptor 4 polymorphisms.
Kumpf, O., Hamann, L., Schlag, P.M. and Schumann, R.R.
Shock 25
: 123-128.
February 2006
Solvent networks tune thermodynamics of oligosaccharide complex formation in an extended protein binding site.
Kunstmann, S., Gohlke, U., Broeker, N.K., Roske, Y., Heinemann, U., Santer, M. and Barbirz, S.
Journal of the American Chemical Society 140
(33): 10447-10455.
22 August 2018
Ablation of TNF or lymphotoxin signaling and the frequency of spontaneous tumors in p53-deficient mice.
Kuprash, D.V., Qin, Z., Ito, D., Grivennikov, S.I., Abe, K., Drutskaya, L.N., Blankenstein, T. and Nedospasov, S.A.
Cancer Letters 268
(1): 70-75.
8 September 2008
Reversal of P-glycoprotein mediated vincristine resistance of L1210/VCR cells by analogues of pentoxifylline - A QSAR study.
Kupsakova, I., Rybar, A., Docolomansky, P., Drobna, Z., Stein, U., Walther, W., Barancik, M. and Breier, A.
European Journal of Pharmaceutical Sciences 21
(2-3): 283-293.
1 January 2004
GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins.
Kupzig, S., Deaconescu, D., Bouyoucef, D., Walker, S.A., Liu, Q., Polte, C.L., Daumke, O., Ishizaki, T., Lockyer, P.J., Wittinghofer, A. and Cullen, P.J.
Journal of Biological Chemistry 281
(15): 9891-900.
14 April 2006
CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance.
Kurobe, H., Liu, C., Ueno, T., Saito, F., Ohigashi, I., Seach, N., Arakaki, R., Hayashi, Y., Kitagawa, T., Lipp, M., Boyd, R.L. and Takahama, Y.
Immunity 24
(2): 165-177.
February 2006
Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection.
Kursar, M., Höpken, U.E., Koch, M., Koehler, A., Lipp, M., Kaufmann, S.H. and Mittrücker, H.W.
Journal of Experimental Medicine 201
(9): 1447-1457.
2 May 2005
Small cell lung cancer stem cells display mesenchymal properties and exploit immune checkpoint pathways in activated cytotoxic T lymphocytes.
Kursunel, M.A., Taskiran, E.Z., Tavukcuoglu, E., Yanik, H., Demirag, F., Karaosmanoglu, B., Ozbay, F.G., Uner, A., Esendagli, D., Kizilgoz, D., Yilmaz, U. and Esendagli, G.
Cancer Immunology Immunotherapy 71
(2): 445-459.
February 2022
A synthetic peptide homologous to functional domain of human IL-10 down-regulates expression of MHC class I and transporter associated with antigen processing 1/2 in human melanoma cells.
Kurte, M., Lopez, M., Aguirre, A., Escobar, A., Aguillon, J.C., Charo, J., Larsen, C.G., Kiessling, R. and Salazar-Onfray, F.
Journal of Immunology 173
(3): 1731-1737.
1 January 2004
Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis.
Kurtova, A.V., Heinlein, M., Haas, S., Velten, L., Dijkgraaf, G.J.P., Storm, E.E., Kljavin, N.M., Boumahdi, S., Himmels, P., Herault, A., Mancini, A.G., Koeppen, H., Dail, M., Yan, M., Zhang, J., Koch, U., Radtke, F., Modrusan, Z., Metcalfe, C., Piskol, R. and de Sauvage, F.J.
Blood Advances 7
(4): 491-507.
28 February 2023
Murine cytomegalovirus M25 proteins sequester the tumor suppressor protein p53 in nuclear accumulations.
Kutle, I., Szymańska-de Wijs, K.M., Bogdanow, B., Cuvalo, B., Steinbrück, L., Jonjić, S., Wagner, K., Niedenthal, R., Selbach, M., Wiebusch, L., Dezeljin, M. and Messerle, M.
Journal of Virology 94
(20): e00574-20.
October 2020
CCR 7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells.
Kuwabara, T., Ishikawa, F., Yasuda, T., Aritomi, K., Nakano, H., Tanaka, Y., Okada, Y., Lipp, M. and Kakiuchi, T.
Journal of Immunology 183
(4): 2513-2521.
15 August 2009
Helicobacter exploits integrin for type IV secretion and kinase activation.
Kwok, T., Zabler, D., Urman, S., Rohde, M., Hartig, R., Wessler, S., Misselwitz, R., Berger, J.M., Sewald, N., Koenig, W. and Backert, S.
Nature 449
(7164): 862-866.
18 October 2007
Sekundäre Immundefekte bei hämatoonkologischen Erkrankungen.
Käbisch, E. and Na, I.K.
Tagliche Praxis 65
(1): 12-23.
2021
Sekundäre Immundefekte bei hämatoonkologischen Erkrankungen [Secondary immunodeficiency in hematological and oncological diseases].
Käbisch, E. and Na, I.K.
Internistische Praxis 63
(4): 570-581.
2021
Health workforce response to Covid-19: What pandemic preparedness planning and action at the federal and state levels in Germany? Germany's health workforce responses to Covid-19.
Köppen, J., Hartl, K. and Maier, C.B.
International Journal of Health Planning and Management 36
(S1): 71-91.
May 2021
Genome-wide genotyping of acute myeloid leukemia with translocation t(9;11)(p22;q23) reveals novel recurrent genomic alterations.
Kühn, M.W.M., Bullinger, L., Gröschel, S., Krönke, J., Edelmann, J., Rücker, F.G., Eiwen, K., Paschka, P., Gaidzik, V.I., Holzmann, K., Schlenk, R.F., Döhner, H. and Döhner, K.
Haematologica 99
(8): 133-135.
August 2014
Genome engineering in rodents - status quo and perspectives.
Kühn, R.
Laboratory Animals 56
(1): 83-87.
1 February 2022
Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.
Künkele, A., De Preter, K., Heukamp, L., Thor, T., Pajtler, K.W., Hartmann, W., Mittelbronn, M., Grotzer, M.A., Deubzer, H.E., Speleman, F., Schramm, A., Eggert, A. and Schulte, J.H.
Neuro-Oncology 14
(7): 859-869.
1 July 2012
MYC-containing amplicons in acute myeloid leukemia: genomic structures, evolution, and transcriptional consequences.
L'Abbate, A., Tolomeo, D., Cifola, I., Severgnini, M., Turchiano, A., Augello, B., Squeo, G., D'Addabbo, P., Traversa, D., Daniele, G., Lonoce, A., Pafundi, M., Carella, M., Palumbo, O., Dolnik, A., Muehlematter, D., Schoumans, J., Van Roy, N., De Bellis, G., Martinelli, G., Merla, G., Bullinger, L., Haferlach, C. and Storlazzi, C.T.
Leukemia 32
(10): 2152-2166.
October 2018
Immuntherapie von Kopf-Hals-Karzinomen - Highlights des ASCO-Kongresses 2015 [Immunotherapy of head and neck tumors: Highlights of the ASCO Meeting 2015].
Laban, S., Doescher, J., Schuler, P.J., Bullinger, L., Brunner, C., Veit, J.A. and Hoffmann, T.K.
HNO 63
(9): 612-619.
September 2015
Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi, V., Peng, S., Klironomos, F., Munschauer, M., Kastelic, N., Chakraborty, T., Schoeler, K., Derudder, E., Martella, M., Mastrobuoni, G., Hernandez-Miranda, L.R., Lahmann, I., Kocks, C., Birchmeier, C., Kempa, S., Quintanilla-Martinez de Fend, L., Landthaler, M., Rajewsky, N. and Rajewsky, K.
Genes & Development 33
: 23-24.
7 November 2019
Amperometric immunosensor for carcinoembryonic antigen in colon cancer samples based on monolayers of dendritic bipodal scaffolds.
Laboria, N., Fragoso, A., Kemmner, W., Latta, D., Nilsson, O., Luz Botero, M., Drese, K. and O'Sullivan, C.K.
Analytical Chemistry 82
(5): 1712-1719.
1 March 2010
Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast.
Lacadie, S.A. and Rosbash, M.
Molecular Cell 19
(1): 65-75.
1 July 2005
In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants.
Lacadie, S.A., Tardiff, D.F., Kadener, S. and Rosbash, M.
Genes & Development 20
(15): 2055-2066.
1 August 2006
The ERGonomics of hematopoietic stem cell self-renewal.
Lacadie, S.A. and Zon, L.I.
Genes & Development 25
(4): 289-293.
15 February 2011
Survey of long-term experiences of sperm cryopreservation in oncological and non-oncological patients: usage and reproductive outcomes of a large monocentric cohort.
Lackamp, N., Wilkemeyer, I., Jelas, I., Keller, U., Bullinger, L., Stintzing, S. and le Coutre, P.
Frontiers in Oncology 11
: 772809.
5 November 2021
Tomo-seq identifies SOX9 as a key regulator of cardiac fibrosis during ischemic injury.
Lacraz, G.P.A., Junker, J.P., Gladka, M.M., Molenaar, B., Scholman, K.T., Vigil-Garcia, M., Versteeg, D., de Ruiter, H., Vermunt, M.W., Creyghton, M.P., Huibers, M.M.H., de Jonge, N., van Oudenaarden, A. and van Rooij, E.
Circulation 136
(15): 1396-1409.
10 October 2017
Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells.
Lacroix, J., Leuchs, B., Li, J., Hristov, G., Deubzer, H.E., Kulozik, A.E., Rommelaere, J., Schlehofer, J.R. and Witt, O.
International Journal of Cancer 127
(5): 1230-1239.
1 September 2010
Thymocyte-dendritic cell interactions near sources of CCR7 ligands in the thymic cortex.
Ladi, E., Schwickert, T.A., Chtanova, T., Chen, Y., Herzmark, P., Yin, X., Aaron, H., Chan, S.W., Lipp, M., Roysam, B. and Robey, E.A.
Journal of Immunology 181
(10): 7014-7023.
15 November 2008
Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule.
Lagresle, C., Bella, C., Daniel, P.T., Krammer, P.H. and Defrance, T.
Journal of Immunology 154
(11): 5746-5756.
1 June 1995
Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I., Bröhl, D., Zyrianova, T., Isomura, A., Czajkowski, M.T., Kapoor, V., Griger, J., Ruffault, P.L., Mademtzoglou, D., Zammit, P.S., Wunderlich, T., Spuler, S., Kühn, R., Preibisch, S., Wolf, J., Kageyama, R. and Birchmeier, C.
Genes & Development 33
(9-10): 524-535.
1 May 2019
A comprehensive comparison of general RNA-RNA interaction prediction methods.
Lai, D. and Meyer, I.M.
Nucleic Acids Research 44
(7): e61.
20 April 2016
e-RNA: a collection of web servers for comparative RNA structure prediction and visualisation.
Lai, D. and Meyer, I.M.
Nucleic Acids Research 42
(Web Server issue): W373-W376.
1 July 2014
R-CHIE: a web server and R package for visualizing RNA secondary structures.
Lai, D., Proctor, J.R., Zhu, J.Y.A. and Meyer, I.M.
Nucleic Acids Research 40
(12): e95.
July 2012
Pathology of ovarian cancers in BRCA1 and BRCA2 carriers.
Lakhani, S.R., Manek, S., Penault-Llorca, F., Flanagan, A., Arnout, L., Merrett, S., McGuffog, L., Steele, D., Devilee, P., Klijn, J.G., Meijers-Heijboer, H., Radice, P., Pilotti, S., Nevanlinna, H., Butzow, R., Sobol, H., Jacquemier, J., Lyonet, D.S., Neuhausen, S.L., Weber, B., Wagner, T., Winqvist, R., Bignon, Y.J., Monti, F., Schmitt, F., Lenoir, G., Seitz, S., Hamman, U., Pharoah, P., Lane, G., Ponder, B., Bishop, D.T. and Easton, D.F.
Clinical Cancer Research 10
(7): 2473-2481.
1 April 2004
Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype.
Lakhani, S.R., Reis-Filho, J.S., Fulford, L., Penault-Llorca, F., van der Vjiver, M., Parry, S., Bishop, T., Benitez, J., Rivas, C., Bignon, Y.J., Chang-Claude, J., Hamann, U., Cornelisse, C.J., Devilee, P., Beckmann, M.W., Nestle-Kramling, C., Daly, P.A., Haites, N., Varley, J., Lalloo, F., Evans, G., Maugard, C., Meijers-Heijboer, H., Klijn, J.G.M., Olah, E., Gusterson, B.A., Pilotti, S., Radice, P., Scherneck, S., Sobol, H., Jacquemier, J., Wagner, T., Peto, J., Stratton, M.R., McGuffog, L. and Easton, D.F.
Clinical Cancer Research 11
(14): 5175-5180.
15 July 2005
Efficient algorithms for training the parameters of hidden Markov models using stochastic expectation maximization (EM) training and Viterbi training.
Lam, T.Y. and Meyer, I.M.
Algorithms for Molecular Biology 5
: 38.
9 December 2010
HMMCONVERTER 1.0: a toolbox for hidden Markov models.
Lam, T.Y. and Meyer, I.M.
Nucleic Acids Research 37
(21): e139.
November 2009
Rapid single-cell identification of Epstein-Barr virus-specific T-cell receptors for cellular therapy.
Lammoglia Cobo, M.F., Welters, C., Rosenberger, L., Leisegang, M., Dietze, K., Pircher, C., Penter, L., Gary, R., Bullinger, L., Takvorian, A., Moosmann, A., Dornmair, K., Blankenstein, T., Kammertöns, T., Gerbitz, A. and Hansmann, L.
Cytotherapy 24
(8): 818-826.
August 2022
Translocation of sickle cell erythrocyte microRNAs into plasmodium falciparum inhibits parasite rranslation and contributes to malaria resistance.
Lamonte, G., Philip, N., Reardon, J., Lacsina, J.R., Majoros, W., Chapman, L., Thornburg, C.D., Telen, M.J., Ohler, U., Nicchitta, C.V., Haystead, T. and Chi, J.T.
Cell Host & Microbe 12
(2): 187-199.
16 August 2012
The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway.
Lamothe, B., Yamada, M., Schaeper, U., Birchmeier, W., Lax, I. and Schlessinger, J.
Molecular and Cellular Biology 24
(13): 5657-5666.
1 January 2004
Repeat-element driven activation of proto-oncogenes in human malignancies.
Lamprecht, B., Bonifer, C. and Mathas, S.
Cell Cycle 9
(21): 4276-4281.
November 2010
Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B., Kreher, S., Anagnostopoulos, I., Joehrens, K., Monteleone, G., Jundt, F., Stein, H., Janz, M., Doerken, B. and Mathas, S.
Blood 112
(8): 3339-3347.
15 October 2008
The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome.
Lamprecht, B., Kreher, S., Moebs, M., Sterry, W., Doerken, B., Janz, M., Assaf, C. and Mathas, S.
British Journal of Dermatology 167
(2): 240-246.
August 2012
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B., Walter, K., Kreher, S., Kumar, R., Hummel, M., Lenze, D., Koechert, K., Bouhlel, M.A., Richter, J., Soler, E., Stadhouders, R., Joehrens, K., Wurster, K.D., Callen, D.F., Harte, M.F., Giefing, M., Barlow, R., Stein, H., Anagnostopoulos, I., Janz, M., Cockerill, P.N., Siebert, R., Doerken, B., Bonifer, C. and Mathas, S.
Nature Medicine 16
(5): 571-579, 1p following 579.
May 2010
Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.
Lan, L., Holland, J.D., Qi, J., Grosskopf, S., Rademann, J., Vogel, R., Gyoerffy, B., Wulf-Goldenberg, A. and Birchmeier, W.
EMBO Journal 34
(11): 1493-1508.
3 June 2015
Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.
Lancini, C., van den Berk, P.C.M., Vissers, J.H.A., Gargiulo, G., Song, J.Y., Hulsman, D., Serresi, M., Tanger, E., Blom, M., Vens, C., van Lohuizen, M., Jacobs, H. and Citterio, E.
Journal of Experimental Medicine 211
(9): 1759-1777.
25 August 2014
Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting.
Lang, K.M., Harrison, K.L., Williamson, P.R., Huntly, B.J.P., Ossenkoppele, G., Geissler, J., Bereczky, T., Hernández-Rivas, J.M., Chevrou-Séverac, H., Goodbody, R., Schulze-Rath, R. and Bullinger, L.
Trials 21
(1): 437.
27 May 2020
Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels.
Lange, C., Schueler, T. and Blankenstein, T.
Journal of Experimental Medicine 187
(9): 1487-1493.
4 May 1998
Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice.
Lange, K., Uckert, W., Blankenstein, T., Nadrowitz, R., Bittner, C., Renauld, J.C., van Snick, J., Feller, A.C. and Merz, H.
Oncogene 22
(4): 517-527.
30 January 2003
Mapping lineage-traced cells across time points with moslin.
Lange, M., Piran, Z., Klein, M., Spanjaard, B., Klein, D., Junker, J.P., Theis, F.J. and Nitzan, M.
Genome Biology 25
(1): 277.
21 October 2024
Development of navigation systems for image-guided laparoscopic tumor resections in liver surgery.
Lange, T., Huenerbein, M., Eulenstein, S., Beller, S. and Schlag, P.M.
Recent Results in Cancer Research 167
: 13-36.
2006
3D ultrasound-CT registration of the liver using combined landmark-intensity information.
Lange, T., Papenberg, N., Heldmann, S., Modersitzki, J., Fischer, B., Lamecker, H. and Schlag, P.M.
International Journal of Computer Assisted Radiology and Surgery 4
(1): 79-88.
January 2009
Landmark constrained non-rigid image registration with anisotropic tolerances.
Lange, T., Papenberg, N., Olesch, J., Fischer, B. and Schlag, P.M.
IFMBE Proceedings 25
(4): 2238-2241.
2009
Registration of different phases of contrast-enhanced CT/MRI data for computer-assisted liver surgery planning: Evaluation of state-of-the-art methods.
Lange, T., Wenckebach, T.H., Lamecker, H., Seebass, M., Huenerbein, M., Eulenstein, S., Gebauer, B. and Schlag, P.M.
International Journal of Medical Robotics and Computer Assisted Surgery 1
: 6-20.
20 September 2005
Landmark-based 3D elastic registration of pre- and postoperative liver CT data: An experimental comparison.
Lange, T., Woerz, S., Rohr, K. and Schlag, P.M.
Informatik aktuell
: 107-111.
2009
A MAS NMR study of the bacterial ABC transporter ArtMP.
Lange, V., Becker-Baldus, J., Kunert, B., van Rossum, B.J., Casagrande, F., Engel, A., Roske, Y., Scheffel, F.M., Schneider, E. and Oschkinat, H.
ChemBioChem 11
(4): 547-555.
1 March 2010
The evolutionary dynamics of extrachromosomal DNA in human cancers.
Lange, J.T., Rose, J.C., Chen, C.Y., Pichugin, Y., Xie, L., Tang, J., Hung, K.L., Yost, K.E., Shi, Q., Erb, M.L., Rajkumar, U., Wu, S., Taschner-Mandl, S., Bernkopf, M., Swanton, C., Liu, Z., Huang, W., Chang, H.Y., Bafna, V., Henssen, A.G., Werner, B. and Mischel, P.S.
Nature Genetics 54
(10): 1527-1533.
October 2022
A new class of distance measures for registration of tubular models to image data.
Lange, T., Lamecker, H., Huenerbein, M., Eulenstein, S., Beller, S. and Schlag, P.M.
Informatik aktuell
: 101-105.
2007
A flexible tool to correct superimposed mass isotopologue distributions in GC-APCI-MS flux experiments.
Langenhan, J., Jaeger, C., Baum, K., Simon, M. and Lisec, J.
Metabolites 12
(5): 408.
29 April 2022
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates.
Langer, H.T., Afzal, S., Kempa, S. and Spuler, S.
Scientific Reports 10
: 1908.
5 February 2020
Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates.
Langer, H.T., Senden, J.M.G., Gijsen, A.P., Kempa, S., van Loon, Luc J. C. and Spuler, S.
Frontiers in Physiology 9
: 1220.
31 August 2018
Targeting the ubiquitin-proteasome system in a pancreatic cancer subtype with hyperactive MYC.
Lankes, K., Hassan, Z.Z., Doffo, M.J., Schneeweis, C., Lier, S., Öllinger, R., Rad, R., Krämer, O.H., Keller, U., Saur, D., Reichert, M., Schneider, G. and Wirth, M.
Molecular Oncology 14
(12): 3048-3064.
December 2020
Sox9 is required for nail bed differentiation and digit tip regeneration.
Lao, M., Hurtado, A., de Castro, A.C., Burgos, M., Jiménez, R. and Barrionuevo, F.J.
Journal of Investigative Dermatology 142
(10): 2613-2622.
October 2022
Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.
Lareau, C.A., Dubois, S.M., Buquicchio, F.A., Hsieh, Y.H., Garg, K., Kautz, P., Nitsch, L., Praktiknjo, S.D., Maschmeyer, P., Verboon, J.M., Gutierrez, J.C., Yin, Y., Fiskin, E., Luo, W., Mimitou, E.P., Muus, C., Malhotra, R., Parikh, S., Fleming, M.D., Oevermann, L., Schulte, J., Eckert, C., Kundaje, A., Smibert, P., Vardhana, S.A., Satpathy, A.T., Regev, A., Sankaran, V.G., Agarwal, S. and Ludwig, L.S.
Nature Genetics 55
(7): 1198-1209.
July 2023
Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility.
Lareau, C.A., Liu, V., Muus, C., Praktiknjo, S.D., Nitsch, L., Kautz, P., Sandor, K., Yin, Y., Gutierrez, J.C., Pelka, K., Satpathy, A.T., Regev, A., Sankaran, V.G. and Ludwig, L.S.
Nature Protocols 18
(5): 1416-1440.
May 2023
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Lareau, C.A., Ludwig, L.S., Muus, C., Gohil, S.H., Zhao, T., Chiang, Z., Pelka, K., Verboon, J.M., Luo, W., Christian, E., Rosebrock, D., Getz, G., Boland, G.M., Chen, F., Buenrostro, J.D., Hacohen, N., Wu, C.J., Aryee, M.J., Regev, A. and Sankaran, V.G.
Nature Biotechnology 39
(4): 451-461.
April 2021
Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking.
Lareau, C.A., Ludwig, L.S. and Sankaran, V.G.
Blood Advances 3
(24): 4161-4165.
23 December 2019
Latent human herpesvirus 6 is reactivated in CAR T cells.
Lareau, C.A., Yin, Y., Maurer, K., Sandor, K.D., Daniel, B., Yagnik, G., Peña, J., Crawford, J.C., Spanjaart, A.M., Gutierrez, J.C., Haradhvala, N.J., Riberdy, J.M., Abay, T., Stickels, R.R., Verboon, J.M., Liu, V., Buquicchio, F.A., Wang, F., Southard, J., Song, R., Li, W., Shrestha, A., Parida, L., Getz, G., Maus, M.V., Li, S., Moore, A., Roberts, Z.J., Ludwig, L.S., Talleur, A.C., Thomas, P.G., Dehghani, H., Pertel, T., Kundaje, A., Gottschalk, S., Roth, T.L., Kersten, M.J., Wu, C.J., Majzner, R.G. and Satpathy, A.T.
Nature 623
: 608-615.
16 November 2023
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation.
Larsen, K.O., Yndestad, A., Sjaastad, I., Loberg, E.M., Goverud, I.L., Halvorsen, B., Jia, J., Andreassen, A.K., Husberg, C., Jonasson, S., Lipp, M., Christensen, G., Aukrust, P. and Skjonsberg, O.H.
American Journal of Physiology Lung Cellular and Molecular Physiology 301
(1): L50-L59.
July 2011
Characterization of colorectal adenocarcinoma sections by spatially resolved FT-IR microspectroscopy.
Lasch, P., Haensch, W., Lewis, E.N., Kidder, L.H. and Naumann, D.
Applied Spectroscopy 56
(1): 1-9.
January 2002
Imaging of colorectal adenocarcinoma using FT-IR microspectroscopy and cluster analysis.
Lasch, P., Haensch, W., Naumann, D. and Diem, M.
Biochimica et Biophysica Acta - Molecular Basis of Disease 1688
: 176-186.
1 January 2004
Artificial neural networks as supervised techniques for FT-IR microspectroscopic imaging.
Lasch, P., Diem, M., Haensch, W. and Naumann, D.
Journal of Chemometrics 20
(5): 209-220.
May 2006
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.
Lauber, C., Correia, N., Trumpp, A., Rieger, M.A., Dolnik, A., Bullinger, L., Roeder, I. and Seifert, M.
Scientific Reports 10
(1): 12761.
29 July 2020
Clinical presentation and management of a dinutuximab beta extravasation in a patient with neuroblastoma.
Launspach, M., Seif, M., Thole, TM., Jesse, P., Schulz, J., Schulte, J.H., Bischoff, S., Eggert, A. and Deubzer, H.E.
Children 8
(2): 91.
29 January 2021
ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO.
Lausen, J., Liu, S., Fliegauf, M., Luebbert, M. and Werner, M.H.
Oncogene 25
(9): 1349-1357.
2 March 2006
Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1.
Lausen, J., Pless, O., Leonard, F., Kuvardina-Bolling, O.N., Koch, B. and Leutz, A.
Journal of Biological Chemistry 285
(8): 5338-5346.
19 February 2010
Chimeric polyomavirus-derived virus-like particles: the immunogenicity of an inserted peptide applied without adjuvant to mice depends on its insertion site and its flanking linker sequence.
Lawatscheck, R., Aleksaite, E., Schenk, J.A., Micheel, B., Jandrig, B., Holland, G., Sasnauskas, K., Gedvilaite, A. and Ulrich, R.G.
Viral Immunology 20
(3): 453-460.
11 October 2007
Efficient CRISPR/Cas9-mediated mutagenesis in primary human B cells for identifying plasma cell regulators.
Le, T.A., Chu, V.T., Lino, A.C., Schrezenmeier, E., Kressler, C., Hamo, D., Rajewsky, K., Dörner, T. and Dang, V.D.
Molecular Therapy - Nucleic Acids 30
: 621-632.
13 December 2022
Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells.
Le, T.T.H., Tran, N.T., Dao, T.M.L., Nguyen, D.D., Do, H.D., Ha, T.L., Kühn, R., Nguyen, T.L., Rajewsky, K. and Chu, V.T.
Frontiers in Genetics 10
: 625.
July 2019
Imatinib in Philadelphia chromosome-positive chronic phase CML patients: molecular and cytogenetic response rates and prediction of clinical outcome.
Le Coutre, P., Kreuzer, K.A., Na, I.K., Schwarz, M., Lupberger, J., Holdhoff, M., Baskaynak, G., Gschaidmeier, H., Platzbecker, U., Ehninger, G., Prejzner, W., Huhn, D. and Schmidt, C.A.
American Journal of Hematology 73
(4): 249-255.
August 2003
Pharmacokinetics and cellular uptake of imatinib and its main metabolite CGP74588.
Le Coutre, P., Kreuzer, K.A., Pursche, S., Bonin, M., Leopold, T., Baskaynak, G., Doerken, B., Ehninger, G., Ottmann, O., Jenke, A., Bornhaeuser, M. and Schleyer, E.
Cancer Chemotherapy and Pharmacology 53
(4): 313-323.
1 April 2004
Different classes of genomic inserts contribute to human antibody diversity.
Lebedin, M., Foglierini, M., Khorkova, S., Vázquez García, C., Ratswohl, C., Davydov, A.N., Turchaninova, M.A., Daubenberger, C., Chudakov, D.M., Lanzavecchia, A. and de la Rosa, K.
Proceedings of the National Academy of Sciences of the United States of America 119
(36): e2205470119.
6 September 2022
Soluble ACE2 correlates with severe COVID-19 and can impair antibody responses.
Lebedin, M., Ratswohl, C., Garg, A., Schips, M., Vazquez Garcia, C., Spatt, L., Thibeault, C., Obermayer, B., Weiner, J., Moreno Velásquez, I., Gerhard, C., Stubbemann, P., Hanitsch, L.G., Pischon, T., Witzenrath, M., Sander, L.E., Kurth, F., Meyer-Hermann, M. and de la Rosa, K.
iScience 27
(3): 109330.
15 March 2024
Discriminating promiscuous from target-specific autoantibodies in COVID-19.
Lebedin, M., Vazquez Garcia, C., Spatt, L., Ratswohl, C., Thibeault, C., Ostendorf, L., Alexander, T., Paul, F., Sander, L.E., Kurth, F. and de la Rosa, K.
European Journal of Immunology 53
(5): e2250210.
May 2023
Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M., Perrod, C., Hoogenkamp, M., Ghani, S., Assi, S., Heinz, S., Wilson, N.K., Follows, G., Schoenheit, J., Vockentanz, L., Mosamam, A., Chen, W., Tenen, D.G., Westhead, D.R., Goettgens, B., Bonifer, C. and Rosenbauer, F.
Blood 117
(10): 2827-2838.
10 March 2011
Metastasis-associated in colon cancer 1 is an independent prognostic biomarker for survival in klatskin tumor patients.
Lederer, A., Herrmann, P., Seehofer, D., Dietel, M., Pratschke, J., Schlag, P. and Stein, U.
Hepatology 62
(3): 841-850.
September 2015
Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.
Lee, J.Y., Colinas, J., Wang, J.Y., Mace, D., Ohler, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 103
(15): 6055-6060.
11 April 2006
Pan-conserved segment tags identify ultra-conserved sequences across assemblies in the human pangenome.
Lee, H., Greer, S.U., Pavlichin, D.S., Zhou, B., Urban, A.E., Weissman, T. and Ji, H.P.
Cell Reports Methods 3
(8): 100543.
28 August 2023
Virus-induced senescence is driver and therapeutic target in COVID-19.
Lee, S., Yu, Y., Trimpert, J., Benthani, F., Mairhofer, M., Richter-Pechanska, P., Wyler, E., Belenki, D., Kaltenbrunner, S., Pammer, M., Kausche, L., Firsching, T.C., Dietert, K., Schotsaert, M., Martínez-Romero, C., Singh, G., Kunz, S., Niemeyer, D., Ghanem, R., Salzer, H.J.F., Paar, C., Mülleder, M., Uccellini, M., Michaelis, E.G., Khan, A., Lau, A., Schönlein, M., Habringer, A., Tomasits, J., Adler, J.M., Kimeswenger, S., Gruber, A.D., Hoetzenecker, W., Steinkellner, H., Purfuerst, B., Motz, R., Di Pierro, F., Lamprecht, B., Osterrieder, N., Landthaler, M., Drosten, C., García-Sastre, A., Langer, R., Ralser, M., Eils, R., Reimann, M., Fan, D.N.Y. and Schmitt, C.A.
Nature 599
: 283-289.
11 November 2021
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann, S.M., Krueger, C., Park, B., Derkow, K., Rosenberger, K., Baumgart, J., Trimbuch, T., Eom, G., Hinz, M., Kaul, D., Habbel, P., Kaelin, R., Franzoni, E., Rybak, A., Nguyen, D., Veh, R., Ninnemann, O., Peters, O., Nitsch, R., Heppner, F.L., Golenbock, D., Schott, E., Ploegh, H.L., Wulczyn, F.G. and Lehnardt, S.
Nature Neuroscience 15
(6): 827-835.
June 2012
Targeting high-grade B cell lymphoma with CD19-specific T cells.
Lehmann, F.M., Maurberger, A., Feicht, S., Helm, F., Ladinig, C., Kieback, E., Uckert, W., Kammertöns, T., Kremmer, E., Mautner, J., Gerbitz, A. and Bornkamm, G.W.
International Journal of Cancer 135
(5): 1153-1164.
1 September 2014
Spatial single cell profiling using imaging mass cytometry: inflammatory versus penetrating Crohn's disease.
Lehmann, M., Weixler, B., Elezkurtaj, S., Loddenkemper, C., Kühl, A.A. and Siegmund, B.
Journal of Crohn's & Colitis 18
(8): 1305-1318.
August 2024
„Deep sequencing“ und praediktive Modellierung als Konzept therapeutischer Entscheidungsfindungen in der Onkologie [Deep sequencing and predictive modeling as a concept for therapeutic decision-making in oncology].
Lehrach, H., Schaefer, R. and Schlag, P. M.
Onkologe 17
(6): 477-486.
June 2011
T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy.
Leisegang, M., Turqueti-Neves, A., Engels, B., Blankenstein, T., Schendel, D.J., Uckert, W. and Noessner, E.
Clinical Cancer Research 16
(8): 2333-2343.
15 April 2010
Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs].
Leisegang, M. and Uckert, W.
BIOspektrum 21
(4): 402-405.
June 2015
MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors.
Leisegang, M., Wilde, S., Spranger, S., Milosevic, S., Frankenberger, B., Uckert, W. and Schendel, D.J.
Journal of Clinical Investigation 120
(11): 3869-3877.
1 November 2010
Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette.
Leisegang, M., Engels, B., Meyerhuber, P., Kieback, E., Sommermeyer, D., Xue, S.A., Reuß, S., Stauss, H. and Uckert, W.
Journal of Molecular Medicine 86
(5): 573-583.
May 2008
Eradication of large solid tumors by gene therapy with a T cell receptor targeting a single cancer-specific point mutation.
Leisegang, M., Engels, B., Schreiber, K., Yew, P.Y., Kiyotani, K., Idel, C., Arina, A., Duraiswamy, J., Weichselbaum, R.R., Uckert, W., Nakamura, Y. and Schreiber, H.
Clinical Cancer Research 22
(11): 2734-2743.
1 June 2016
Targeting human melanoma neoantigens by T cell receptor gene therapy.
Leisegang, M., Kammertoens, T., Uckert, W. and Blankenstein, T.
Journal of Clinical Investigation 126
(3): 854-858.
1 March 2016
The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.
Leisegang, M.S., Gu, L., Preussner, J., Günther, S., Hitzel, J., Ratiu, C., Weigert, A., Chen, W., Schwarz, E.C., Looso, M., Fork, C. and Brandes, R.P.
FEBS Letters 593
(5): 487-498.
March 2019
Technologies for profiling the impact of genomic variants on transcription factor binding.
Leiz, J., Rutkiewicz, M., Birchmeier, C., Heinemann, U. and Schmidt-Ott, K.M.
Medizinische Genetik 33
(2): 147-155.
14 August 2021
Assessing the utility of thermodynamic features for microRNA target prediction under relaxed seed and no conservation requirements.
Lekprasert, P., Mayhew, M. and Ohler, U.
PLoS ONE 6
(6): e20622.
6 June 2011
Cryo-electron tomography reveals four-membrane architecture of the Plasmodium apicoplast.
Lemgruber, L., Kudryashev, M., Dekiwadia, C., Riglar, D.T., Baum, J., Stahlberg, H., Ralph, S.A. and Frischknecht, F.
Malaria Journal 12
: 25.
19 January 2013
Thiamine is a substrate of organic cation transporters in Caco-2 cells.
Lemos, C., Faria, A., Meireles, M., Martel, F., Monteiro, R. and Calhau, C.
European Journal of Pharmacology 682
(1-3): 37-42.
5 May 2012
Anti-metastatic treatment in colorectal cancer: targeting signaling pathways.
Lemos, C., Sack, U., Schmid, F., Juneja, M. and Stein, U.
Current Pharmaceutical Design 19
(5): 841-863.
February 2013
MACC1 induces tumor progression in transgenic mice and colorectal cancer patients via increased pluripotency markers Nanog and Oct4.
Lemos, C., Hardt, M.S., Juneja, M., Voss, C., Foerster, S., Jerchow, B., Haider, W., Blaker, H. and Stein, U.
Clinical Cancer Research 22
(11): 2812-2824.
1 June 2016
Clinical and prognostic relevance of cardiac wasting in patients with advanced cancer.
Lena, A., Wilkenshoff, U., Hadzibegovic, S., Porthun, J., Rösnick, L., Fröhlich, A.K., Zeller, T., Karakas, M., Keller, U., Ahn, J., Bullinger, L., Riess, H., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Totzeck, M., Rassaf, T., Burkhoff, D., Mehra, M.R., Bax, J.J., Butler, J., Edelmann, F., Haverkamp, W., Anker, S.D., Packer, M., Coats, A.J.S., von Haehling, S., Landmesser, U. and Anker, M.S.
Journal of the American College of Cardiology 81
(16): 1569-1586.
25 April 2023
Immunomodulatory analogs of thalidomide inhibit growth of Hs Sultan cells and angiogenesis in vivo.
Lentzsch, S., LeBlanc, R., Podar, K., Davies, F., Lin, B., Hideshima, T., Catley, L., Stirling, D.I. and Anderson, K.C.
Leukemia 17
: 41-44.
1 January 2003
PI3-K/AKT/FKHR and MAPK signaling cascades are redundantly stimulated by a variety of cytokines and contribute independently to proliferation and survival of multiple myeloma cells.
Lentzsch, S., Chatterjee, M., Gries, M., Bommert, K., Gollasch, H., Doerken, B. and Bargou, R.C.
Leukemia 18
(11): 1883-1890.
1 January 2004
Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S., Gries, M., Janz, M., Bargou, R., Doerken, B. and Mapara, M.Y.
Blood 101
(9): 3568-3573.
1 May 2003
The chloroplast RNA binding protein CP31A has a preference for mRNAs encoding the subunits of the chloroplast NAD(P)H dehydrogenase complex and is required for their accumulation.
Lenzen, B., Rühle, T., Lehniger, M.K., Okuzaki, A., Labs, M., Muino, J.M., Ohler, U., Leister, D. and Schmitz-Linneweber, C.
International Journal of Molecular Sciences 21
(16): 5633.
6 August 2020
Hepatobiliary long-term consequences of COVID-19: dramatically increased rate of secondary sclerosing cholangitis in critically ill COVID-19 patients.
Leonhardt, S., Jürgensen, C., Frohme, J., Grajecki, D., Adler, A., Sigal, M., Leonhardt, J., Voll, J.M., Kruse, J.M., Körner, R., Eckardt, K.U., Janssen, H.J., Gebhardt, V., Schmittner, M.D., Frey, C., Müller-Ide, H., Bauer, M., Thibeault, C., Kurth, F., Sander, L.E., Müller, T. and Tacke, F.
Hepatology International 17
(6): 1610-1625.
December 2023
Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype.
Leppä, A.M., Grimes, K., Jeong, H., Huang, F.Y., Andrades, A., Waclawiczek, A., Boch, T., Jauch, A., Renders, S., Stelmach, P., Müller-Tidow, C., Karpova, D., Sohn, M., Grünschläger, F., Hasenfeld, P., Benito Garagorri, E., Thiel, V., Dolnik, A., Rodriguez-Martin, B., Bullinger, L., Mrózek, K., Eisfeld, A.K., Krämer, A., Sanders, A.D., Korbel, J.O. and Trumpp, A.
Nature Genetics 56
(12): 2790-2803.
December 2024
Impact of prior treatment on outcome of transformed follicular lymphoma and relapsed de novo diffuse large B cell lymphoma: a retrospective multicentre analysis.
Lerch, K., Meyer, A.H., Stroux, A., Hirt, C., Keller, U., Viardot, A., Marks, R., Schreiber, S., Pezzutto, A. and Scholz, C.W.
Annals of Hematology 94
(6): 981-988.
June 2015
Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M., Wang, Y.H., Kaufmann, U., Gerbeth, L., Sand, A., Brunkhorst, M., Weidner, P., Ziegler, J.F., Böttcher, C., Schlickeiser, S., Fernández, C., Yamashita, M., Stauderman, K., Sun, K., Kunkel, D., Prakriya, M., Sanders, A.D., Siegmund, B., Feske, S. and Weidinger, C.
EMBO Molecular Medicine 14
(9): e15687.
7 September 2022
CMV-specific central memory T cells reside in bone marrow.
Letsch, A., Knoedler, M., Na, I.K., Kern, F., Asemissen, A.M., Keilholz, U., Loesch, M., Thiel, E., Volk, H.D. and Scheibenbogen, C.
European Journal of Immunology 37
(11): 3063-3068.
November 2007
Molecular genetics of hematopoiesis & leukemogenesis.
Leutz, A.
Zellbiologie Aktuell 30
(3): 16-18.
May 2004
Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs.
Leutz, A., Pless, O., Lappe, M., Dittmar, G. and Kowenz-Leutz, E.
Transcription 2
(1): 3-8.
January 2011
Using SMOG 2 to simulate complex biomolecular assemblies.
Levi, M., Bandarkar, P., Yang, H., Wang, A., Mohanty, U., Noel, J.K. and Whitford, P.C.
Methods in Molecular Biology 2022
: 129-151.
2019
Studying ribosome dynamics with simplified models.
Levi, M., Noel, J.K. and Whitford, P.C.
Methods 162-163
: 128-140.
1 June 2019
Survival of Igα-deficient mature B cells requires BAFF-R function.
Levit-Zerdoun, E., Becker, M., Pohlmeyer, R., Wilhelm, I., Maity, P.C., Rajewsky, K., Reth, M. and Hobeika, E.
Journal of Immunology 196
(5): 2348-2360.
1 March 2016
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism.
Levy, T., Voeltzke, K., Hruby, L., Alasad, K., Bas, Z., Snaebjörnsson, M., Marciano, R., Scharov, K., Planque, M., Vriens, K., Christen, S., Funk, C.M., Hassiepen, C., Kahler, A., Heider, B., Picard, D., Lim, J.K.M., Stefanski, A., Bendrin, K., Vargas-Toscano, A., Kahlert, U.D., Stühler, K., Remke, M., Elkabets, M., Grünewald, T.G.P., Reichert, A.S., Fendt, S.M., Schulze, A., Reifenberger, G., Rotblat, B. and Leprivier, G.
Nature Communications 15
(1): 4083.
14 May 2024
Investigation of spleen CXCR4 expression by [(68)Ga]Pentixafor PET in a cohort of 145 solid cancer patients.
Lewis, R., Habringer, S., Kircher, M., Hefter, M., Peuker, C.A., Werner, R., Ademaj-Kospiri, V., Gäble, A., Weber, W., Wester, H.J., Buck, A., Herhaus, P., Lapa, C. and Keller, U.
EJNMMI Research 11
(1): 77.
21 August 2021
CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness.
Lewis, R., Maurer, H.C., Singh, N., Gonzalez-Menendez, I., Wirth, M., Schick, M., Zhang, L., Isaakidis, K., Scherger, A.K., Schulze, V., Lu, J., Zenz, T., Steiger, K., Rad, R., Quintanilla-Martinez, L., Espeli, M., Balabanian, K., Keller, U. and Habringer, S.
Leukemia 35
: 2895-2905.
October 2021
The location of small tumor deposits in the SLN predicts Non-SLN macrometastases in breast cancer patients.
Li, J., Haensch, W., Rudas, M., Kemmner, W., Warnick, P., Fischer, J., Gnant, M., Schlag, P.M. and Bembenek, A.
European Journal of Surgical Oncology 34
(8): 857-862.
August 2008
Generation of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast-embryonic stem cell fusion.
Li, L. and Blankenstein, T.
Nature Protocols 8
(8): 1567-1582.
August 2013
Transgenic mice with a diverse human T cell antigen receptor repertoire.
Li, L.P., Lampert, J.C., Chen, X., Leitao, C., Popovic, J., Mueller, W. and Blankenstein, T.
Nature Medicine 16
(9): 1029-1034.
September 2010
SV40 large T antigen-transformed human primary normal and cancerous mammary epithelial cells are phenotypically similar but can be distinguished in 3D culture with selection medium.
Li, L.P., Willimsky, G., Seitz, S., Xu, Y., Li, Y., Schwarz, L.E., Schlag, P.M. and Blankenstein, T.
International Journal of Cancer 123
(7): 1516-1525.
1 October 2008
Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
Li, M., Jung, A., Ganswindt, U., Marini, P., Friedl, A., Daniel, P.T., Lauber, K., Jendrossek, V. and Belka, C.
Biochemical Pharmacology 79
(2): 122-129.
15 January 2010
CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse.
Li, Q.J., Dinner, A.R., Qi, S., Irvine, D.J., Huppa, J.B., Davis, M.M. and Chakraborty, A.K.
Nature Immunology 5
(8): 791-9.
1 August 2004
Solving the inverse problem of microscopy deconvolution with a residual Beylkin-Coifman-Rokhlin neural network.
Li, R., Kudryashev, M. and Yakimovich, A.
Lecture Notes in Computer Science 15133
: 378-395.
1 November 2024
A customized class of functions for modeling and clustering gene expression profiles in embryonic stem cells.
Li, S., Andrade-Navarro, M. and Sankoff, D.
Lecture Notes in Computer Science 5167
: 92-103.
2008
Integrated detection of natural antisense transcripts using strand-specific RNA sequencing data.
Li, S., Liberman, L., Mukherjee, N., Benfey, P. and Ohler, U.
Genome Research 23
(10): 1730-1739.
October 2013
Expansion and precise CRISPR-Cas9 gene repair of autologous T memory stem cells from patients with T cell immunodeficiencies.
Li, X., Chu, V.T., Kocks, C. and Rajewsky, K.
Bio-protocol 14
(20): e5085.
20 October 2024
A weak-labelling and deep learning approach for in-focus object segmentation in 3D widefield microscopy.
Li, R., Kudryashev, M. and Yakimovich, A.
Scientific Reports 13
(1): 12275.
28 July 2023
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Li, S., Garrett-Bakelman, F.E., Chung, S.S., Sanders, M.A., Hricik, T., Rapaport, F., Patel, J., Dillon, R., Vijay, P., Brown, A.L., Perl, A.E., Cannon, J., Bullinger, L., Luger, S., Becker, M., Lewis, I.D., To, L.B., Delwel, R., Löwenberg, B., Döhner, H., Döhner, K., Guzman, M.L., Hassane, D.C., Roboz, G.J., Grimwade, D., Valk, P.J.M., D'Andrea, R.J., Carroll, M., Park, C.Y., Neuberg, D., Levine, R., Melnick, A.M. and Mason, C.E.
Nature Medicine 22
(7): 792-9.
July 2016
High-resolution expression map of the arabidopsis root reveals alternative splicing and lincRNA regulation.
Li, S., Yamada, M., Han, X., Ohler, U. and Benfey, P.N.
Developmental Cell 39
(4): 508-522.
21 November 2016
Precise CRISPR-Cas9 gene repair in autologous memory T cells to treat familial hemophagocytic lymphohistiocytosis.
Li, X., Wirtz, T., Weber, T., Lebedin, M., Lowenstein, E.D., Sommermann, T., Zach, A., Yasuda, T., de la Rosa, K., Chu, V.T., Schulte, J.H., Müller, I., Kocks, C. and Rajewsky, K.
Science Immunology 9
(92): eadi0042.
2 February 2024
Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D., Oshima, M., Stange, D.E. and Sigal, M.
Gastroenterology 162
(4): 1067-1087.
April 2022
A single TCRα-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire.
Liang, X., Weigand, L.U., Schuster, I.G., Eppinger, E., van der Griendt, J.C., Schub, A., Leisegang, M., Sommermeyer, D., Anderl, F., Han, Y., Ellwart, J., Moosmann, A., Busch, D.H., Uckert, W., Peschel, C. and Krackhardt, A.M.
Journal of Immunology 184
(3): 1617-1629.
1 February 2010
Staphylococcus aureus physiological growth limitations: insights from flux calculations built on proteomics and external metabolite data.
Liang, C., Liebeke, M., Schwarz, R., Zuehlke, D., Fuchs, S., Menschner, L., Engelmann, S., Wolz, C., Jaglitz, S., Bernhardt, J., Hecker, M., Lalk, M. and Dandekar, T.
Proteomics 11
(10): 1915-1935.
May 2011
Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma.
Liang, H.C., Costanza, M., Prutsch, N., Zimmerman, M.W., Gurnhofer, E., Montes-Mojarro, I.A., Abraham, B.J., Prokoph, N., Stoiber, S., Tangermann, S., Lobello, C., Oppelt, J., Anagnostopoulos, I., Hielscher, T., Pervez, S., Klapper, W., Zammarchi, F., Silva, D.A., Garcia, K.C., Baker, D., Janz, M., Schleussner, N., Fend, F., Pospíšilová, Š., Janiková, A., Wallwitz, J., Stoiber, D., Simonitsch-Klupp, I., Cerroni, L., Pileri, S., de Leval, L., Sibon, D., Fataccioli, V., Gaulard, P., Assaf, C., Knörr, F., Damm-Welk, C., Woessmann, W., Turner, S.D., Look, A.T., Mathas, S., Kenner, L. and Merkel, O.
Nature Communications 12
(1): 5577.
22 September 2021
A draft human pangenome reference.
Liao, W.W., Asri, M., Ebler, J., Doerr, D., Haukness, M., Hickey, G., Lu, S., Lucas, J.K., Monlong, J., Abel, H.J., Buonaiuto, S., Chang, X.H., Cheng, H., Chu, J., Colonna, V., Eizenga, J.M., Feng, X., Fischer, C., Fulton, R.S., Garg, S., Groza, C., Guarracino, A., Harvey, W.T., Heumos, S., Howe, K., Jain, M., Lu, T.Y., Markello, C., Martin, F.J., Mitchell, M.W., Munson, K.M., Mwaniki, M.N., Novak, A.M., Olsen, H.E., Pesout, T., Porubsky, D., Prins, P., Sibbesen, J.A., Sirén, J., Tomlinson, C., Villani, F., Vollger, M.R., Antonacci-Fulton, L.L., Baid, G., Baker, C.A., Belyaeva, A., Billis, K., Carroll, A., Chang, P.C., Cody, S., Cook, D.E., Cook-Deegan, R.M., Cornejo, O.E., Diekhans, M., Ebert, P., Fairley, S., Fedrigo, O., Felsenfeld, A.L., Formenti, G., Frankish, A., Gao, Yan, Garrison, N.A., Giron, C.G., Green, R.E., Haggerty, L., Hoekzema, K., Hourlier, T., Ji, H.P., Kenny, E.E., Koenig, B.A., Kolesnikov, A., Korbel, J.O., Kordosky, J., Koren, S., Lee, H.J., Lewis, A.P., Magalhães, H., Marco-Sola, S., Marijon, P., McCartney, A., McDaniel, J., Mountcastle, J., Nattestad, M., Nurk, S., Olson, N.D., Popejoy, A.B., Puiu, D., Rautiainen, M., Regier, A.A., Rhie, A., Sacco, S., Sanders, A.D., Schneider, V.A., Schultz, B.I., Shafin, K., Smith, M.W., Sofia, H.J., Abou Tayoun, A.N., Thibaud-Nissen, F., Tricomi, F.F., Wagner, J., Walenz, B., Wood, J.M.D., Zimin, A.V., Bourque, G., Chaisson, M.J P, Flicek, Paul, Phillippy, A.M., Zook, J.M., Eichler, E.E., Haussler, D., Wang, T., Jarvis, E.D., Miga, K.H., Garrison, E., Marschall, T., Hall, I.M., Li, H. and Paten, B.
Nature 617
(7960): 312-324.
11 May 2023
MicroRNA signature helps distinguish early from late biochemical failure in prostate cancer.
Lichner, Z., Fendler, A., Saleh, C., Nasser, A.N., Boles, D., Al-Haddad, S., Kupchak, P., Dharsee, M., Nuin, P.S., Evans, K.R., Jung, K., Stephan, C., Fleshner, N.E. and Yousef, G.M.
Clinical Chemistry 59
(11): 1595-1603.
November 2013
Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose.
Licht, A., Bulut, H., Scheffel, F.M., Daumke, O., Wehmeier, U.F., Saenger, W., Schneider, E. and Vahedi-Faridi, A.
Journal of Molecular Biology 406
(1): 92-105.
11 February 2011
Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas.
Liebers, N., Duell, J., Fitzgerald, D., Kerkhoff, A., Noerenberg, D., Kaebisch, E., Acker, F., Fuhrmann, S., Leng, C., Welslau, M., Chemnitz, J., Middeke, J.M., Weber, T., Holtick, U., Trappe, R., Pfannes, R., Liersch, R., Spoer, C., Fuxius, S., Gebauer, N., Caillé, L., Geer, T., Koenecke, C., Keller, U., Claus, R., Mougiakakos, D., Mayer, S., Huettmann, A., Pott, C., Trummer, A., Wulf, G., Brunnberg, U., Bullinger, L., Hess, G., Mueller-Tidow, C., Glass, B., Lenz, G., Dreger, P. and Dietrich, S.
Blood Advances 5
(13): 2707-2716.
13 July 2021
Mapping the MHC class I spliced immunopeptidome of cancer cells.
Liepe, J., Sidney, J., Lorenz, F.K.M., Sette, A. and Mishto, M.
Cancer Immunology Research 7
(1): 62-76.
January 2019
Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis.
Lietz, A., Janz, M., Sigvardsson, M., Jundt, F., Doerken, B. and Mathas, S.
British Journal of Haematology 137
(4): 342-348.
May 2007
The MTE, a new core promoter element for transcription by RNA polymerase II.
Lim, C.Y., Santoso, B., Boulay, T., Dong, E., Ohler, U. and Kadonaga, J.T.
Genes & Development 18
(13): 1606-1617.
1 July 2004
Cell surface α2,6-sialylation affects adhesion of breast carcinoma cells.
Lin, S.Q., Kemmner, W., Grigull, S. and Schlag, P.M.
Experimental Cell Research 276
(1): 101-110.
15 May 2002
Mako: a graph-based pattern growth approach to detect complex structural variants.
Lin, J., Yang, X., Kosters, W., Xu, T., Jia, Y., Wang, S., Zhu, Q., Ryan, M., Guo, L., Zhang, C., Lee, C., Devine, S.E., Eichler, E.E. and Ye, K.
Genomics, Proteomics and Bioinformatics 20
(1): 205-218.
February 2022
Fusion of SpCas9 to E.coli Rec A protein enhances CRISPR-Cas9 mediated gene knockout in mammalian cells.
Lin, L., Petersen, T.S., Jensen, K.T., Bolund, L., Kühn, R. and Luo, Y.
Journal of Biotechnology 247
: 42-49.
10 April 2017
Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M., Hartl, K., Heuberger, J., Beccaceci, G., Berger, H., Li, H., Liu, L., Müllerke, S., Conrad, T., Heymann, F., Woehler, A., Tacke, F., Rajewsky, N. and Sigal, M.
Nature Communications 14
(1): 3025.
25 May 2023
Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill.
Lin, X., Noel, J.K., Wang, Q., Ma, J. and Onuchic, J.N.
Proceedings of the National Academy of Sciences of the United States of America 115
(34): E7905-E7913.
21 August 2018
Lowered pH leads to fusion peptide release and a highly dynamic intermediate of influenza hemagglutinin.
Lin, X.C., Noel, J.K., Wang, Q.H., Ma, J.P. and Onuchic, J.N.
Journal of Physical Chemistry B 120
(36): 9654-9660.
15 September 2016
CD4+ T cell-mediated HER-2/neu-specific tumor rejection in the absence of B cells.
Lindencrona, J.A., Preiss, S., Kammertoens, T., Schueler, T., Piechocki, M., Wei, W.Z., Seliger, B., Blankenstein, T. and Kiessling, R.
International Journal of Cancer 109
(2): 259-264.
1 January 2004
ALK pERKs up MYCN in neuroblastoma.
Lindner, S., Henssen, A., Astrahantseff, K. and Schulte, J.H.
Science Signaling 7
(349): pe27.
28 October 2014
Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia.
Ling, V.Y., Straube, J., Godfrey, W., Haldar, R., Janardhanan, Y., Cooper, L., Bruedigam, C., Cooper, E., Tavakoli Shirazi, P., Jacquelin, S., Tey, S.K., Baell, J., Huang, F., Jin, J., Zhao, Y., Bullinger, L., Bywater, M.J. and Lane, S.W.
Leukemia 37
(1): 143-153.
January 2023
Clinical relevance of circulating MACC1 and S100A4 transcripts for ovarian cancer.
Link, T., Kuhlmann, J.D., Kobelt, D., Herrmann, P., Vassileva, Y., Kramer, M., Frank, K., Göckenjan, M., Wimberger, P. and Stein, U.
Molecular Oncology 13
(5): 1268-1279.
May 2019
High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann, C., Heemskerk, B., Kvistborg, P., Kluin, R.J.C., Bolotin, D.A., Chen, X., Bresser, K., Nieuwland, M., Schotte, R., Michels, S., Gomez-Eerland, R., Jahn, L., Hombrink, P., Legrand, N., Shu, C.J., Mamedov, I.Z., Velds, A., Blank, C.U., Haanen, J.B.A.G., Turchaninova, M.A., Kerkhoven, R.M., Spits, H., Hadrup, S.R., Heemskerk, M.H.M., Blankenstein, T., Chudakov, D.M., Bendle, G.M. and Schumacher, T.N.M.
Nature Medicine 19
(11): 1534-1541.
November 2013
Effective inhibitor removal from wastewater samples increases sensitivity of RT-dPCR and sequencing analyses and enhances the stability of wastewater-based surveillance.
Linzner, N., Bartel, A., Schumacher, V., Grau, J.H., Wyler, E., Preuß, H., Garske, S., Bitzegeio, J., Kirst, E.B., Liere, K., Hoppe, S., Borodina, T.A., Altmüller, J., Landthaler, M., Meixner, M., Sagebiel, D. and Böckelmann, U.
Microorganisms 12
(12): 2475.
December 2024
Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing.
Lipka, D.B., Wang, Q., Cabezas-Wallscheid, N., Klimmeck, D., Weichenhan, D., Herrmann, C., Lier, A., Brocks, D., von Paleske, L., Renders, S., Wünsche, P., Zeisberger, P., Gu, L., Haas, S., Essers, M.A., Brors, B., Eils, R., Trumpp, A., Milsom, M.D. and Plass, C.
Cell Cycle 13
(22): 3476-3487.
10 December 2014
Shaping up adaptive immunity: the impact of CCR7 and CXCR5 on lymphocyte trafficking.
Lipp, M. and Mueller, G.
Verhandlungen der Deutschen Gesellschaft fuer Pathologie 87
: 90-101.
1 January 2003
Who with whom: functional coordination of E2 enzymes by RING E3 ligases during poly-ubiquitylation.
Lips, C., Ritterhoff, T., Weber, A., Janowska, M.K., Mustroph, M., Sommer, T. and Klevit, R.E.
EMBO Journal 39
(22): e104863.
16 November 2020
Extending the dynamic range in metabolomics experiments by automatic correction of peaks exceeding the detection limit.
Lisec, J., Hoffmann, F., Schmitt, C. and Jaeger, C.
Analytical Chemistry 88
(15): 7487-7492.
2 August 2016
Systematic identification of MACC1-driven metabolic networks in colorectal cancer.
Lisec, J., Kobelt, D., Walther, W., Mokrizkij, M., Grötzinger, C., Jaeger, C., Baum, K., Simon, M., Wolf, J., Beindorff, N., Brenner, W. and Stein, U.
Cancers 13
(5): 978.
26 February 2021
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Lisowski, P., Lickfett, S., Rybak-Wolf, A., Menacho, C., Le, S., Pentimalli, T.M., Notopoulou, S., Dykstra, W., Oehler, D., López-Calcerrada, S., Mlody, B., Otto, M., Wu, H., Richter, Y., Roth, P., Anand, R., Kulka, L.A.M., Meierhofer, D., Glazar, P., Legnini, I., Telugu, N.S., Hahn, T., Neuendorf, N., Miller, D.C., Böddrich, A., Polzin, A., Mayatepek, E., Diecke, S., Olzscha, H., Kirstein, J., Ugalde, C., Petrakis, S., Cambridge, S., Rajewsky, N., Kühn, R., Wanker, E.E., Priller, J., Metzger, J.J. and Prigione, A.
Nature Communications 15
(1): 7027.
22 August 2024
Fas expression by tumor stroma is required for cancer eradication.
Listopad, J.J., Kammertoens, T., Anders, K., Silkenstedt, B., Willimsky, G., Schmidt, K., Kuehl, A.A., Loddenkemper, C. and Blankenstein, T.
Proceedings of the National Academy of Sciences of the United States of America 110
(6): 2276-2281.
5 February 2013
Coordination between CCR7- and CCR9-mediated chemokine signals in pre-vascular fetal thymus colonization.
Liu, C., Saito, F., Liu, Z., Lei, Y., Uehara, S., Love, P., Lipp, M., Kondo, S., Manley, N. and Takahama, Y.
Blood 108
(8): 2531-2539.
15 October 2006
Role of CCL21 in recruitment of T precursor cells to fetal thymus.
Liu, C., Ueno, T., Kuse, S., Saito, F., Nitta, T., Piali, L., Nakano, H., Kakiuchi, T., Lipp, M., Hollander, G.A. and Takahama, Y.
Blood 105
(1): 31-39.
1 January 2005
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis.
Liu, F., Chu, E.Y., Watt, B., Zhang, Y., Gallant, N.M., Andl, T., Yang, S.H., Lu, M.M., Piccolo, S., Schmidt-Ullrich, R., Taketo, M.M., Morrisey, E.E., Atit, R., Dlugosz, A.A. and Millar, S.E.
Developmental Biology 313
(1): 210-224.
1 January 2008
Stability and homogeneity of transgene expression in isogenic cells.
Liu, W., Xiong, Y. and Gossen, M.
Journal of Molecular Medicine 84
(1): 57-64.
January 2006
SLAM-Drop-seq reveals mRNA kinetic rates throughout the cell cycle.
Liu, H., Arsiè, R., Schwabe, D., Schilling, M., Minia, I., Alles, J., Boltengagen, A., Kocks, C., Falcke, M., Friedman, N., Landthaler, M. and Rajewsky, N.
Molecular Systems Biology 19
(10): e11427.
12 October 2023
Structural basis for membrane tethering by a bacterial dynamin-like pair.
Liu, J., Noel, J.K. and Low, H.H.
Nature Communications 9
(1): 3345.
21 August 2018
Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily.
Liu, J., Tassinari, M., Souza, D.P., Naskar, S., Noel, J.K., Bohuszewicz, O., Buck, M., Williams, T.A., Baum, B. and Low, H.H.
Cell 184
(14): 3660-3673.
8 July 2021
Social media big data-based research on the influencing factors of insomnia and spatiotemporal evolution.
Liu, Y., Luo, Q., Shen, H., Zhuang, S., Xu, C., Dong, Y., Sun, Y., Wang, S. and Deng, H.
IEEE Access 8
: 41516-41529.
28 February 2020
Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.
Lluch, A., Latorre, J., Serena-Maione, A., Espadas, I., Caballano-Infantes, E., Moreno-Navarrete, J.M., Oliveras-Cañellas, N., Ricart, W., Malagón, M.M., Martin-Montalvo, A., Birchmeier, W., Szymanski, W., Graumann, J., Gómez-Serrano, M., Sommariva, E., Fernández-Real, J.M. and Ortega, F.J.
Nature Communications 14
(1): 5106.
22 August 2023
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
Lo, W.T., Belabed, H., Kücükdisli, M., Metag, J., Roske, Y., Prokofeva, P., Ohashi, Y., Horatscheck, A., Cirillo, D., Krauss, M., Schmied, C., Neuenschwander, M., von Kries, J.P., Médard, G., Kuster, Be., Perisic, O., Williams, R.L., Daumke, O., Payrastre, B., Severin, S., Nazaré, M. and Haucke, V.
Nature Chemical Biology 19
(1): 18-27.
January 2023
Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo, W.T., Zhang, Y., Vadas, O., Roske, Y., Gulluni, F., De Santis, M.C., Zagar, A.V., Stephanowitz, H., Hirsch, E., Liu, F., Daumke, O., Kudryashev, M. and Haucke, V.
Nature Structural & Molecular Biology 29
(3): 218-228.
March 2022
Getting CD19 into shape: expression of natively folded "difficult-to-express" CD19 for staining and stimulation of CAR-T cells.
Lobner, E., Wachernig, A., Gudipati, V., Mayrhofer, P., Salzer, B., Lehner, M., Huppa, J.B. and Kunert, R.
Frontiers in Bioengineering and Biotechnology 8
: 49.
7 February 2020
Differential Emu enhancer activity and expression of BOB.1/OBF.1, Oct2, PU.1, and immunoglobulin in reactive B-cell populations, B-cell non-Hodgkin lymphomas, and Hodgkin lymphomas.
Loddenkemper, C., Anagnostopoulos, L., Hummel, M., Joehrens-Leder, K., Foss, H.D., Jundt, F., Wirth, T., Doerken, B. and Stein, H.
Journal of Pathology 202
(5): 60-69.
1 January 2004
Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D., Pahuja, A., Geers-Knörr, C., Scheibe, R., Nowak, M., Hamati, J., Köhncke, C., Purfürst, B., Kanashova, T., Schmidt, S., Glass, D.J., Morano, I., Heuser, A., Kraft, T., Bassel-Duby, R., Olson, E.N., Dittmar, G., Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7
(2): 165-180.
May 2016
CD19-targeting CAR T cells protect from ANCA-induced acute kidney injury.
Lodka, D., Zschummel, M., Bunse, M., Rousselle, A., Sonnemann, J., Kettritz, R., Höpken, U.E. and Schreiber, A.
Annals of the Rheumatic Diseases 83
(4): 499-507.
12 March 2024
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
Lodrini, M., Oehme, I., Schroeder, C., Milde, T., Schier, M.C., Kopp-Schneider, A., Schulte, J.H., Fischer, M., De Preter, K., Pattyn, F., Castoldi, M., Muckenthaler, M.U., Kulozik, A.E., Westermann, F., Witt, O. and Deubzer, H.E.
Nucleic Acids Research 41
(12): 6018-6033.
1 July 2013
Minichromosome maintenance complex is a critical node in the miR-183 signaling network of MYCN-amplified neuroblastoma cells.
Lodrini, M., Poschmann, G., Schmidt, V., Wünschel, J., Dreidax, D., Witt, O., Höfer, T., Meyer, H.E., Stühler, K., Eggert, A. and Deubzer, H.E.
Journal of Proteome Research 15
(7): 2178-2186.
1 July 2016
Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma.
Lodrini, M., Sprüssel, A., Astrahantseff, K., Tiburtius, D., Konschak, R., Lode, H.N., Fischer, M., Keilholz, U., Eggert, A. and Deubzer, H.E.
Oncotarget 8
(49): 85234-85251.
17 October 2017
Circulating cell-free DNA assessment in biofluids from children with neuroblastoma demonstrates feasibility and potential for minimally invasive molecular diagnostics.
Lodrini, M., Wünschel, J., Thole-Kliesch, T.M., Grimaldi, M., Sprüssel, A., Linke, R.B., Hollander, J.F., Tiburtius, D., Künkele, A., Schulte, J.H., Lankes, E., Elgeti, T., Hundsdörfer, P., Astrahantseff, K., Simon, T., Eggert, A. and Deubzer, H.E.
Cancers 14
(9): 2080.
21 April 2022
Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19/anti-CD3 single-chain antibody construct.
Loeffler, A., Gruen, M., Wuchter, C., Schriever, F., Kufer, P., Dreier, T., Hanakam, F., Baeuerle, P.A., Bommert, K., Karawajew, L., Doerken, B. and Bargou, R.C.
Leukemia 17
(5): 900-909.
May 2003
Testing of SNS-032 in a panel of human neuroblastoma cell lines with acquired resistance to a broad range of drugs.
Loeschmann, N., Michaelis, M., Rothweiler, F., Zehner, R., Cinatl, J., Voges, Y., Sharifi, M., Riecken, K., Meyer, J., von Deimling, A., Fichtner, I., Ghafourian, T., Westermann, F. and Cinatl Jr., J.
Translational Oncology 6
(6): 685-696.
December 2013
Construction, rescue, and characterization of vectors derived from ovine atadenovirus.
Loeser, P., Hofmann, C., Both, G.W., Uckert, W. and Hillgenberg, M.
Journal of Virology 77
(22): 11941-11951.
November 2003
Improved Tet-responsive promoters with minimized background expression.
Loew, R., Heinz, N., Hampf, M., Bujard, H. and Gossen, M.
BMC Biotechnology 10
(1): 81.
24 November 2010
Microglia sense neuronal activity via GABA in the early postnatal hippocampus.
Logiacco, F., Xia, P., Georgiev, S.V., Franconi, C., Chang, Y.J., Ugursu, B., Sporbert, A., Kühn, R., Kettenmann, H. and Semtner, M.
Cell Reports 37
(13): 110128.
28 December 2021
Thermostability and Ca2+ binding properties of wild type and heterologously expressed PsbO protein from cyanobacterial photosystem II.
Loll, B., Gerold, G., Slowik, D., Voelter, W., Jung, C., Saenger, W. and Irrgang, K.D.
Biochemistry 44
(12): 4691-4698.
1 January 2005
Tissue specific subnetworks and characteristics of publicly available human protein interaction databases.
Lopes, T.J., Schaefer, M., Shoemaker, J., Matsuoka, Y., Fontaine, J.F., Neumann, G., Andrade-Navarro, M.A., Kawaoka, Y. and Kitano, H.
Bioinformatics 27
(17): 2414-2421.
1 September 2011
Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas.
Lopez, C., Schleussner, N., Bernhart, S.H., Kleinheinz, K., Sungalee, S., Sczakiel, H.L., Kretzmer, H., Toprak, U.H., Glaser, S., Wagener, R., Ammerpohl, O., Bens, S., Giefing, M., Sanchez, J.C.G., Apic, G., Hubschmann, D., Janz, M., Kreuz, M., Mottok, A., Müller, J.M., Seufert, J., Hoffmann, S., Korbel, J.O., Russell, R.B., Schule, R., Trumper, L., Klapper, W., Radlwimmer, B., Lichter, P., Kuppers, R., Schlesner, M., Mathas, S. and Siebert, R.
Haematologica 108
(2): 543-554.
1 February 2023
Therapie des Magenkarzinoms [Treatment of gastric cancer].
Lordick, F., Ridwelski, K., Al-Batran, S.E., Trarbach, T., Schlag, P.M. and Piso, P.
Onkologie 31
(Suppl 5): 32-39.
November 2008
Molekulare Prognosefaktoren und neue systemische Therapien bei Magenkarzinomen [Molecular prognostic factors and new systemic therapies in gastric cancer].
Lordick, F. and Schulze, T.
Onkologe 14
(4): 389-395.
April 2008
Regulation of Ras localization by acylation enables a mode of intracellular signal propagation.
Lorentzen, A., Kinkhabwala, A., Rocks, O., Vartak, N. and Bastiaens, P.I.
Science Signaling 3
(140): ra68.
21 September 2010
Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7.
Lorenz, F.K.M., Wilde, S., Voigt, K., Kieback, E., Mosetter, B., Schendel, D.J. and Uckert, W.
PLoS ONE 10
(3): e0121633.
23 March 2015
Unbiased identification of T cell receptors targeting immunodominant peptide-MHC complexes for T cell receptor immunotherapy.
Lorenz, F.K.M., Ellinger, C., Kieback, E., Wilde, S., Lietz, M., Schendel, D.J. and Uckert, W.
Human Gene Therapy 28
(12): 1158-1168.
1 December 2017
Different promoter affinities account for specificity in MYC-dependent gene regulation.
Lorenzin, F., Benary, U., Baluapuri, A., Walz, S., Jung, L.A., von Eyss, B., Kisker, C., Wolf, J., Eilers, M. and Wolf, E.
eLife 5
: e15161.
27 July 2016
IL-10 controls ultraviolet-induced carcinogenesis in mice.
Loser, K., Apelt, J., Voskort, M., Mohaupt, M., Balkow, S., Schwarz, T., Grabbe, S. and Beissert, S.
Journal of Immunology 179
(1): 365-371.
1 July 2007
Lineage commitment of hematopoietic stem cells and progenitors: insights from recent single cell and lineage tracing technologies.
Loughran, S.J., Haas, S., Wilkinson, A.C., Klein, A.M. and Brand, M.
Experimental Hematology 88
: 1-6.
August 2020
Prediction of protein secondary structure from circular dichroism using theoretically derived spectra.
Louis-Jeune, C., Andrade-Navarro, M.A. and Perez-Iratxeta, C.
Proteins: Structure, Function, and Bioinformatics 80
(2): 374-381.
February 2012
Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts.
Lovas, A., Radke, D., Albrecht, D., Yilmaz, Z.B., Moeller, U., Habenicht, A.J. and Weih, F.
BMC Genomics 9
: 606.
16 December 2008
Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
Lowenstein, E.D., Ruffault, P.L., Misios, A., Osman, K.L., Li, H., Greenberg, R.S., Thompson, R., Song, K., Dietrich, S., Li, X., Vladimirov, N., Woehler, A., Brunet, J.F., Zampieri, N., Kühn, R., Liberles, S.D., Jia, S., Lewin, G.R., Rajewsky, N., Lever, T.E. and Birchmeier, C.
Neuron 111
(14): 2184-2200.e7.
19 July 2023
Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients.
Lu, H., Busch, J., Jung, M., Rabenhorst, S., Ralla, B., Kilic, E., Mergemeier, S., Budach, N., Fendler, A. and Jung, K.
Clinica Chimica Acta 452
: 109-119.
15 January 2016
Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.
Lu, S.X., Kappel, L.W., Charbonneau-Allard, A.M., Atallah, R., Holland, A.M., Turbide, C., Hubbard, V.M., Rotolo, J.A., Smith, M., Suh, D., King, C., Rao, U.K., Yim, N., Bautista, J.L., Jenq, R.R., Penack, O., Na, I.K., Liu, C., Murphy, G., Alpdogan, O., Blumberg, R.S., Macian, F., Holmes, K.V., Beauchemin, N. and van den Brink, M.R.M.
PLoS ONE 6
(7): e21611.
6 July 2011
HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.
Lucas, B., Grigo, K., Erdmann, S., Lausen, J., Klein-Hitpass, L. and Ryffel, G.U.
Oncogene 24
(42): 6418-6431.
22 September 2005
Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: Results of the German multicenter trials GMALL 03/87 and 04/89.
Ludwig, W.D., Rieder, H., Bartram, C.R., Heinze, B., Schwartz, S., Gassmann, W., Loeffler, H., Hossfeld, D., Heil, G., Handt, S., Heyll, A., Diedrich, H., Fischer, K., Weiss, A., Voelkers, B., Aydemir, U., Fonatsch, C., Goekbuget, N., Thiel, E. and Hoelzer, D.
Blood 92
(6): 1898-1909.
15 September 1998
Aberrant DNA methylation in ES cells.
Ludwig, G., Nejman, D., Hecht, M., Orlanski, S., Abu-Remaileh, M., Yanuka, O., Sandler, O., Marx, A., Roberts, D., Benvenisty, N., Bergman, Y., Mendelsohn, M. and Cedar, H.
PLoS ONE 9
(5): e96090.
22 May 2014
Einfluss genetischer Varianten auf die humane Erythropoese [Influence of genetic variants on human erythropoiesis].
Ludwig, L.S.
BIOspektrum 22
(7): 768-769.
November 2016
Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
Ludwig, L.S., Cho, H., Wakabayashi, A., Eng, J.C., Ulirsch, J.C., Fleming, M.D., Lodish, H.F. and Sankaran, V.G.
American Journal of Hematology 90
(5): 386-91.
May 2015
Altered translation of GATA1 in Diamond-Blackfan anemia.
Ludwig, L.S., Gazda, H.T., Eng, J.C., Eichhorn, S.W., Thiru, P., Ghazvinian, R., George, T.I., Gotlib, J.R., Beggs, A.H., Sieff, C.A., Lodish, H.F., Lander, E.S. and Sankaran, V.G.
Nature Medicine 20
(7): 748-753.
July 2014
Concomitant sequencing of accessible chromatin and mitochondrial genomes in single cells using mtscATAC-seq.
Ludwig, L.S. and Lareau, C.A.
Methods in Molecular Biology 2611
: 269-282.
2023
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig, L.S., Lareau, C.A., Bao, E.L., Liu, N., Utsugisawa, T., Tseng, A.M., Myers, S.A., Verboon, J.M., Ulirsch, J.C., Luo, W., Muus, C., Fiorini, C., Olive, M.E., Vockley, C.M., Munschauer, M., Hunter, A., Ogura, H., Yamamoto, T., Inada, H., Nakagawa, S., Ozono, S., Subramanian, V., Chiarle, R., Glader, B., Carr, S.A., Aryee, M.J., Kundaje, A., Orkin, S., Regev, A., McCavit, T., Kanno, H. and Sankaran, V.G.
Blood 139
(16): 2534-2546.
21 April 2022
Transcriptional states and chromatin accessibility underlying human erythropoiesis.
Ludwig, L.S., Lareau, C.A., Bao, E.L., Nandakumar, S.K., Muus, C., Ulirsch, J.C., Chowdhary, K., Buenrostro, J.D., Mohandas, N., An, X., Aryee, M.J., Regev, A. and Sankaran, V.G.
Cell Reports 27
(11): 3228-3240.
11 June 2019
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics.
Ludwig, L.S., Lareau, C.A., Ulirsch, J.C., Christian, E., Muus, C., Li, L.H., Pelka, K., Ge, W., Oren, Y., Brack, A., Law, T., Rodman, C., Chen, J.H., Boland, G.M., Hacohen, N., Rozenblatt-Rosen, O., Aryee, M.J., Buenrostro, J.D., Regev, A. and Sankaran, V.G.
Cell 176
(6): 1325-1339.
7 March 2019
Continuous glucose monitoring in children, adolescents, and adults with type 1 diabetes mellitus: analysis from the prospective DPV diabetes documentation and quality management system from Germany and Austria.
Ludwig-Seibold, C.U., Holder, M., Rami, B., Raile, K., Heidtmann, B. and Holl, R.W.
Pediatric Diabetes 13
(1): 12-14.
February 2012
Reverse transformation of human mammary carcinoma cells.
Luebbe, L., Schenk, J.A., Naundorf, H., Karsten, U. and Wunderlich, V.
Anticancer Research 19
(6B): 5119-5125.
November 1999
Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers.
Lueck, S.C., Russ, A.C., Botzenhardt, U., Schlenk, R.F., Zobel, K., Deshayes, K., Vucic, D., Döhner, H., Döhner, K., Fulda, S. and Bullinger, L.
Oncotarget 7
(31): 49539-49551.
2 August 2016
BCL-1/cyclin D1 oncoprotein oscillates and subverts the G1 phase control in B-cell neoplasms carrying the t(11;14) translocation.
Lukas, J., Jadayel, D., Bartkova, J., Nacheva, E., Dyer, M.J.S., Strauss, M. and Bartek, J.
Oncogene 9
(8): 2159-2167.
August 1994
DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cells requirement for cyclin D1 function in G1.
Lukas, J., Mueller, H., Bartkova, J., Spitkovsky, D.D., Kjerulff, A.A., Jansen-Duerr, P., Strauss, M. and Bartek, J.
Journal of Cell Biology 125
(3): 625-638.
May 1994
Taste mapping: navigating the spatiotemporal link between diet and colorectal cancer.
Luo, Q., Liu, Y., Bi, M., Kuai, X., Tian, Q., Sun, Y. and Zhuang, S.
IEEE Access 12
: 17735 - 17747.
30 January 2024
Pattern and density of vascularization in mammalian testes, ovaries, and ovotestes.
Lupianez, D.G., Real, F.M., Dadhich, R.K., Carmona, F.D., Burgos, M., Barrionuevo, F.J. and Jimenez, R.
Journal of Experimental Zoology Part B : Molecular and Developmental Evolution 318
(3): 170-181.
May 2012
Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions.
Lupiáñez, D.G., Kraft, K., Heinrich, V., Krawitz, P., Brancati, F., Klopocki, E., Horn, D., Kayserili, H., Opitz, J.M., Laxova, R., Santos-Simarro, F., Gilbert-Dussardier, B., Wittler, L., Borschiwer, M., Haas, S.A., Osterwalder, M., Franke, M., Timmermann, B., Hecht, J., Spielmann, M., Visel, A. and Mundlos, S.
Cell 161
(5): 1012-1025.
21 May 2015
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik, P., Baude, A., Mancarella, D., Öz, S., Kühn, A., Toth, R., Hey, J., Toprak, U.H., Lim, J., Nguyen, V.H., Jiang, C., Mayakonda, A., Hartmann, M., Rosemann, F., Breuer, K., Vonficht, D., Grünschläger, F., Lee, S., Schuhmacher, M.K., Kusevic, D., Jauch, A., Weichenhan, D., Zustin, J., Schlesner, M., Haas, S., Park, J.H., Park, Y.J., Oppermann, U., Jeltsch, A., Haller, F., Fellenberg, J., Lindroth, A.M. and Plass, C.
Nature Communications 11
(1): 5414.
27 October 2020
Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.
Lutter, D., Ullrich, F., Lueck, J.C., Kempa, S. and Jentsch, T.J.
Journal of Cell Science 130
(6): 1122-1133.
15 March 2017
A pilot study of prophylactic donor lymphocyte infusions to prevent relapse in adult acute lymphoblastic leukemias after allogeneic hematopoietic stem cell transplantation.
Lutz, C., Massenkeil, G., Nagy, M., Neuburger, S., Tamm, I., Rosen, O., Doerken, B. and Arnold, R.
Bone Marrow Transplantation 41
(9): 805-812.
May 2008
Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy.
Lutz, R., Grünschläger, F., Simon, M., Awwad, M.H.S., Bauer, M., Yousefian, S., Beumer, N., Jopp-Saile, L., Sedlmeier, A., Solé-Boldo, L., Avanesyan, B., Vonficht, D., Stelmach, P., Steinbuss, G., Boch, T., Steiger, S., Baertsch, M.A., Prokoph, N., Rippe, K., Durie, B.G.M., Wickenhauser, C., Trumpp, A., Müller-Tidow, C., Hübschmann, D., Weinhold, N., Raab, M.S., Brors, B., Goldschmidt, H., Imbusch, C.D., Hundemer, M. and Haas, S.
Nature Communications 15
(1): 10396.
29 November 2024
Deregulated expression of circular RNAs in acute myeloid leukemia.
Lux, S., Blätte, T.J., Gillissen, B., Richter, A., Cocciardi, S., Skambraks, S., Schwarz, K., Schrezenmeier, H., Döhner, H., Döhner, K., Dolnik, A. and Bullinger, L.
Blood Advances 5
(5): 1490-1503.
9 March 2021
Circular RNAs in cancer.
Lux, S. and Bullinger, L.
Advances in Experimental Medicine and Biology 1087
: 215-230.
28 September 2018
Tongue immune compartment analysis reveals spatial macrophage heterogeneity.
Lyras, E.M., Zimmermann, K., Wagner, L.K., Dörr, D., Klose, C.S.N, Fischer, C., Jung, S., Yona, S., Hovav, A.H., Stenzel, W., Dommerich, S., Conrad, T., Leutz, A. and Mildner, A.
eLife 11
: 77490.
24 June 2022
Single-molecule mRNA detection and counting in mammalian tissue.
Lyubimova, A., Itzkovitz, S., Junker, J.P., Fan, Z.P., Wu, X. and van Oudenaarden, A.
Nature Protocols 8
(9): 1743-1758.
September 2013
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
López, S., Lim, E.L., Horswell, S., Haase, K., Huebner, A., Dietzen, M., Mourikis, T.P., Watkins, T.B.K., Rowan, A., Dewhurst, S.M., Birkbak, N.J., Wilson, G.A., Van Loo, P., Jamal-Hanjani, M., Swanton, C. and McGranahan, N.
Nature Genetics 52
(3): 283-293.
March 2020
Analysis of correlation and ionization from pair distributions in many-electron systems.
López-Rosa, S., Angulo, J. C., Martín, A. L. and Antolín, J.
European Physical Journal Plus 136
(7): 763.
22 July 2021
Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.
Löber, U., Hobbs, M., Dayaram, A., Tsangaras, K., Jones, K., Alquezar-Planas, D.E., Ishida, Y., Meers, J., Mayer, J., Quedenau, C., Chen, W., Johnson, R.N., Timms, P., Young, P.R., Roca, A.L. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 115
(34): 8609-8614.
21 August 2018
A comprehensive molecular profiling approach reveals metabolic alterations that steer bone tissue regeneration.
Löffler, J., Noom, A., Ellinghaus, A., Dienelt, A., Kempa, S. and Duda, G.N.
Communications Biology 6
(1): 327.
27 March 2023
In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans.
Ma, L., Tan, Z., Teng, Y., Hoersch, S. and Horvitz, H.R.
RNA 17
(12): 2201-2211.
December 2011
Transcriptome-wide identification of RNA-binding protein binding sites using photoactivatable-ribonucleoside-enhanced crosslinking immunoprecipitation (PAR-CLIP).
Maatz, H., Kolinski, M., Hubner, N. and Landthaler, M.
Current Protocols in Molecular Biology 118
: 27.6.1-27.6.19.
3 April 2017
Prohibitin promotes dedifferentiation and is a potential therapeutic target in neuroblastoma.
MacArthur, I.C., Bei, Y., Garcia, H.D., Ortiz, M.V., Toedling, J., Klironomos, F., Rolff, J., Eggert, A., Schulte, J.H., Kentsis, A. and Henssen, A.G.
JCI Insight 4
(10): e127130.
16 May 2019
Quantification of transcription factor expression from Arabidopsis images.
Mace, D.L., Lee, J.Y., Twigg, R.W., Colinas, J., Benfey, P.N. and Ohler, U.
Bioinformatics 22
(14): e323-231.
15 July 2006
Extraction and comparison of gene expression patterns from 2D RNA in situ hybridization images.
Mace, D.L., Varnado, N., Zhang, W., Frise, E. and Ohler, U.
Bioinformatics 26
(6): 761-769.
15 March 2010
Extensive identification and analysis of conserved small ORFs in animals.
Mackowiak, S.D., Zauber, H., Bielow, C., Thiel, D., Kutz, K., Calviello, L., Mastrobuoni, G., Rajewsky, N., Kempa, S., Selbach, M. and Obermayer, B.
Genome Biology 16
: 179.
14 September 2015
Rat cytomegalovirus efficiently replicates in dendritic cells and induces changes in their transcriptional profile.
Madela-Mönchinger, J.C., Wolf, S.A., Wyler, E., Bauer, A., Mischke, M., Möller, L., Juranić Lisnić, V., Landthaler, M., Malyshkina, A. and Voigt, S.
Frontiers in Immunology 14
: 1192057.
23 November 2023
Genomic inversions and GOLGA core duplicons underlie disease instability at the 15q25 locus.
Maggiolini, F.A.M., Cantsilieris, S., D'Addabbo, P., Manganelli, M., Coe, B.P., Dumont, B.L., Sanders, A.D., Pang, A.W.C., Vollger, M.R., Palumbo, O., Palumbo, P., Accadia, M., Carella, M., Eichler, E.E. and Antonacci, F.
PLoS Genetics 15
(3): e1008075.
27 March 2019
Single-cell strand sequencing of a macaque genome reveals multiple nested inversions and breakpoint reuse during primate evolution.
Maggiolini, F.A.M., Sanders, A.D., Shew, C.J., Sulovari, A., Mao, Y., Puig, M., Catacchio, C.R., Dellino, M., Palmisano, D., Mercuri, L., Bitonto, M., Porubský, D., Cáceres, M., Eichler, E.E., Ventura, M., Dennis, M.Y., Korbel, J.O. and Antonacci, F.
Genome Research 30
(11): 1680-1693.
November 2020
An integrated understanding of the molecular mechanisms how adipose tissue metabolism affects long-term body weight maintenance.
Mai, K., Li, L., Wiegand, S., Brachs, M., Leupelt, V., Ernert, A., Kühnen, P., Hübner, N., Robinson, P., Chen, W., Krude, H. and Spranger, J.
Diabetes 68
(1): 57-65.
1 January 2019
Inter and intraobserver variability in DePalma's classification of shoulder calcific tendinitis.
Maier, M., Maier-Bosse, T., Schulz, C.U., Steinborn, M., Schmitt, C.A., Kleen, M. and Staebler, A.
Journal of Rheumatology 30
(5): 1029-1031.
May 2003
Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Maifrede, S., Nieborowska-Skorska, M., Sullivan-Reed, K., Dasgupta, Y., Podszywalow-Bartnicka, P., Le, B.V., Solecka, M., Lian, Z., Belyaeva, E.A., Nersesyan, A., Machnicki, M.M., Toma, M., Chatain, N., Rydzanicz, M., Zhao, H., Jelinek, J., Piwocka, K., Sliwinski, T., Stoklosa, T., Ploski, R., Fischer, T., Sykes, S.M., Koschmieder, S., Bullinger, L., Valent, P., Wasik, M.A., Huang, J. and Skorski, T.
Blood 132
(1): 67-77.
5 July 2018
Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity.
Mailer, R.K., Falk, K. and Roetzschke, O.
PLoS ONE 4
(7): e6104.
1 July 2009
Improving the quality of electron tomography image volumes using pre-reconstruction filtering.
Maiorca, M., Hanssen, E., Kazmierczak, E., Maco, B., Kudryashev, M., Hall, R., Quiney, H. and Tilley, L.
Journal of Structural Biology 180
(1): 132-142.
October 2012
Improved transcript isoform discovery using ORF graphs.
Majoros, W.H., Lebeck, N., Ohler, U. and Li, S.
Bioinformatics 30
(14): 1958-1964.
15 July 2014
Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs.
Majoros, W.H. and Ohler, U.
PLoS Computational Biology 6
(12): e1001037.
16 December 2010
Complexity reduction in context-dependent DNA substitution models.
Majoros, W.H. and Ohler, U.
Bioinformatics 25
(2): 175-182.
15 January 2009
Spatial preferences of microRNA targets in 3' untranslated regions.
Majoros, W.H. and Ohler, U.
BMC Genomics 8
: 152.
7 June 2007
A framework for ultra-low-input spatial tissue proteomics.
Makhmut, A., Qin, D., Fritzsche, S., Nimo, J., König, J. and Coscia, F.
Cell Systems 14
(11): 1002-1014.
15 November 2023
An automated and fast sample preparation workflow for laser microdissection guided ultrasensitive proteomics.
Makhmut, A., Qin, D., Hartlmayr, D., Seth, A. and Coscia, F.
Molecular & Cellular Proteomics 23
(5): 100750.
May 2024
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
Malanchi, I., Peinado, H., Kassen, D., Hussenet, T., Metzger, D., Chambon, P., Huber, M., Hohl, D., Cano, A., Birchmeier, W. and Huelsken, J.
Nature 452
(7187): 650-653.
3 April 2008
Structure-based screening of tetrazolylhydrazide inhibitors versus KDM4 histone demethylases.
Malecki, P.H., Rueger, N., Roatsch, M., Krylova, O., Link, A., Jung, M., Heinemann, U. and Weiss, M.S.
ChemMedChem 14
(21): 1828-1839.
6 November 2019
Single-cell multi-omics analysis identifies context-specific gene regulatory gates and mechanisms.
Malekpour, S.A., Haghverdi, L. and Sadeghi, M.
Briefings in Bioinformatics 25
(3): bbae180.
May 2024
RIF1 regulates early replication timing in murine B cells.
Malzl, D., Peycheva, M., Rahjouei, A., Gnan, S., Klein, K.N., Nazarova, M., Schoeberl, U.E., Gilbert, D.M., Buonomo, S.C.B., Di Virgilio, M., Neumann, T. and Pavri, R.
Nature Communications 14
(1): 8049.
11 December 2023
Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold.
Manjasetty, B.A., Buessow, K., Fieber-Erdmann, M., Roske, Y., Gobom, J., Scheich, C., Goetz, F., Niesen, F.H. and Heinemann, U.
Protein Science 15
(4): 914-920.
1 April 2006
Crystal structure of Homo sapiens protein hp14.5.
Manjasetty, B.A., Delbrueck, H., Pham, D.T., Mueller, U., Fieber-Erdmann, M., Scheich, C., Sievert, V., Buessow, K., Niesen, F.H., Weihofen, W., Loll, B., Saenger, W. and Heinemann, U.
Proteins: Structure, Function, and Bioinformatics 54
(3): 797-800.
1 March 2004
Structure of circularly permuted DsbAQ100T99: preserved global fold and local structural adjustments.
Manjasetty, B.A., Hennecke, J., Glockshuber, R. and Heinemann, U.
Acta Crystallographica Section D 60
(2): 304-309.
1 January 2004
Secure web book to store structural genomics research data.
Manjasetty, B.A., Hoppner, K., Mueller, U. and Heinemann, U.
Journal of Structural and Functional Genomics 4
(2-3): 121-127.
1 January 2003
X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880.
Manjasetty, B.A., Niesen, F.H., Delbrueck, H., Goetz, F., Sievert, V., Buessow, K., Behlke, J. and Heinemann, U.
Biological Chemistry 385
(10): 935-942.
1 January 2004
X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
Manjasetty, B.A., Niesen, F.H., Scheich, C., Roske, Y., Goetz, F., Behlke, J., Sievert, V., Heinemann, U. and Buessow, K.
BMC Structural Biology 5
(14): 21.
14 December 2005
X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma.
Manjasetty, B.A., Quedenau, C., Sievert, V., Buessow, K., Niesen, F., Delbrueck, H. and Heinemann, U.
Proteins: Structure, Function, and Bioinformatics 55
(1): 214-217.
April 2004
A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in caenorhabditis elegans.
Mansisidor, A.R., Cecere, G., Hoersch, S., Jensen, M.B., Kawli, T., Kennedy, L.M., Chavez, V., Tan, M.W., Lieb, J.D. and Grishok, A.
PLoS Genetics 7
(9): e1002299.
September 2011
A new approach for the treatment of malignant melanoma: Enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2.
Mansour, A.M., Drevs, J., Esser, N., Hamada, F.M., Badary, O.A., Unger, C., Fichtner, I. and Kratz, F.
Cancer Research 63
(14): 4062-4066.
15 July 2003
Disassembly of Lys11- and mixed-linkage polyubiquitin conjugates provide insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.
Mansour, W., Nakasone, M.A., von Delbrück, M., Yu, Z., Krutauz, D., Reis, N., Kleifeld, O., Sommer, T., Fushman, D. and Glickman, M.H.
Journal of Biological Chemistry 290
(8): 4688-4704.
20 February 2015
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungstroem, V., Schneider, M., Yoshida, K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C.M., Couronne, L., Lenze, D., Baldus, C.D., Bastard, C., Okosun, J., Fitzgibbon, J., Doerken, B., Drexler, H.G., Roos-Weil, D., Schmitt, C.A., Munch-Petersen, H.D., Zenz, T., Hansmann, M.L., Strefford, J.C., Enblad, G., Bernard, O.A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Gronbaek, K., Lopez-Guillermo, A., Ogawa, S., Kueppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R.M., Ott, G., Vassilakopoulos, T.P., Hummel, M., Rosenquist, R. and Damm, F.
Blood 128
(23): 2666-2670.
15 December 2016
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.
Mansouri, L., Thorvaldsdottir, B., Sutton, L.A., Karakatsoulis, G., Meggendorfer, M., Parker, H., Nadeu, F., Brieghel, C., Laidou, S., Moia, R., Rossi, D., Catherwood, M., Kotaskova, J., Delgado, J., Rodríguez-Vicente, A.E., Benito, R., Rigolin, G.M., Bonfiglio, S., Scarfo, L., Mattsson, M., Davis, Z., Gogia, A., Rani, L., Baliakas, P., Foroughi-Asl, H., Jylhä, C., Skaftason, A., Rapado, I., Miras, F., Martinez-Lopez, J., de la Serna, J., Rivas, J.M.H., Thornton, P., Larráyoz, M.J., Calasanz, M.J., Fésüs, V., Mátrai, Z., Bödör, C., Smedby, K.E., Espinet, B., Puiggros, A., Gupta, R., Bullinger, L., Bosch, F., Tazón-Vega, B., Baran-Marszak, F., Oscier, D., Nguyen-Khac, F., Zenz, T., Terol, M.J., Cuneo, A., Hernández-Sánchez, M., Pospisilova, S., Mills, K., Gaidano, G., Niemann, C.U., Campo, E., Strefford, J.C., Ghia, P., Stamatopoulos, K. and Rosenquist, R.
Leukemia 37
(2): 339-347.
February 2023
APO-1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: correlation with bcl-2 oncogene expression.
Mapara, M.Y., Bargou, R.C., Zugck, C. ., Doehner, H., Ustaoglu, F., Jonker, R.R., Krammer, P.H. and Doerken, B.
European Journal of Immunology 23
(3): 702-708.
March 1993
Monitoring of tumor cell purging after highly efficient immunomagnetic selection of CD34 cells from leukapheresis products in breast cancer patients: comparision of immunocytochemical tumor cells staining and RT-PCR.
Mapara, M.Y., Koerner, I.J., Hildebrandt, M., Bargou, R.C., Krahl, D., Reichardt, P. and Doerken, B.
Blood 89
(1): 337-344.
1 January 1997
Involvement of NAK-1, the human nur77 homologue, in surface IgM-mediated apoptosis in Burkitt lymphoma cell line BL41.
Mapara, M.Y., Weinmann, P., Bommert, K., Daniel, P.T., Bargou, R.C. and Doerken, B.
European Journal of Immunology 25
(9): 2506-2510.
September 1995
G protein subunit G alpha16 expression is restricted to progenitor B-cells during human B-cell differentiation.
Mapara, M.Y., Bommert, K., Bargou, R.C., Leng, C., Beck, C., Ludwig, W.D., Gierschik, P. and Doerken, B.
Blood 85
(7): 1836-1842.
1 April 1995
Donor lymphocyte infusion-mediated graft-versus-leukemia effects in mixed chimeras established with a nonmyeloablative conditioning regimen: extinction of graft-versus-leukemia effects after conversion to full donor chimerism.
Mapara, M.Y., Kim, Y.M., Marx, J. and Sykes, M.
Transplantation 76
: 297-305.
27 July 2003
Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia.
Mar, B.G., Bullinger, L.B., McLean, K.M., Grauman, P.V., Harris, M.H., Stevenson, K., Neuberg, D.S., Sinha, A.U., Sallan, S.E., Silverman, L.B., Kung, A.L., Lo Nigro, L., Ebert, B.L. and Armstrong, S.A.
Nature Communications 5
: 3469.
24 March 2014
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto, A., Ohmura, S., Orth, M.F., Knott, M.M.L., Colombo, M.V., Arrigoni, C., Bardinet, V., Saucier, D., Wehweck, F.S., Li, J., Stein, S., Gerke, J.S., Baldauf, M.C., Musa, J., Dallmayer, M., Romero-Pérez, L., Hölting, T.L.B., Amatruda, J.F., Cossarizza, A., Henssen, A.G., Kirchner, T., Moretti, M., Cidre-Aranaz, F., Sannino, G. and Grünewald, T.G.P.
Nature Communications 11
(1): 2423.
15 May 2020
SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma.
Mardin, W.A., Petrov, K.O., Enns, A., Senninger, N., Haier, J. and Mees, S.T.
BMC Cancer 10
: 549.
12 October 2010
Sarcolemmal repair is a slow process and includes EHD2.
Marg, A., Schoewel, V., Timmel, T., Schulze, A., Shah, C., Daumke, O. and Spuler, S.
Traffic 13
(9): 1286-1294.
September 2012
In vitro Kinase-to-Phosphosite database (iKiP-DB) predicts kinase activity in phosphoproteomic datasets.
Mari, T., Mösbauer, K., Wyler, E., Landthaler, M., Drosten, C. and Selbach, M.
Journal of Proteome Research 21
(6): 1575-1587.
3 June 2022
'Chemical analogues' of HLA-DM can induce a peptide-receptive state in HLA-DR molecules.
Marin-Esteban, V., Falk, K. and Roetzschke, O.
Journal of Biological Chemistry 279
(49): 50684-50690.
20 September 2004
Small-molecular compounds enhance the loading of APC with encephalitogenic MBP protein.
Marin-Esteban, V., Falk, K. and Roetzschke, O.
Journal of Autoimmunity 20
(1): 63-69.
February 2003
Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo.
Marini, P., Denzinger, S., Schiller, D., Kauder, S., Welz, S., Humphreys, R., Daniel, P.T., Jendrossek, V., Budach, W. and Belka, C.
Oncogene 25
: 5145-5154.
24 August 2006
Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis.
Marini, P., Schmid, A., Jendrossek, V., Faltin, H., Daniel, P.T., Budach, W. and Belka, C.
BMC Cancer 5
: 5.
14 January 2005
Structure-based humanization of a therapeutic antibody for multiple myeloma.
Marino, S.F. and Daumke, O.
Journal of Molecular Medicine 102
(9): 1151-1161.
September 2024
A complex water network contributes to high-affinity binding in an antibody-antigen interface.
Marino, S.F., Olal, D. and Daumke, O.
Data in Brief 6
: 394-397.
March 2016
Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F., Jerke, U., Rolle, S., Daumke, O. and Kettritz, R.
Journal of Biological Chemistry 298
(3): 101598.
March 2022
Locus specific epigenetic modalities of random allelic expression imbalance.
Marion-Poll, L., Forêt, B., Zielinski, D., Massip, F., Attia, M., Carter, A.C., Syx, L., Chang, H.Y., Gendrel, A.V. and Heard, E.
Nature Communications 12
(1): 5330.
9 September 2021
GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data.
Markowski, J., Kempfer, R., Kukalev, A., Irastorza-Azcarate, I., Loof, G., Kehr, B., Pombo, A., Rahmann, S. and Schwarz, R.F.
Bioinformatics 37
(19): 3128–3135.
1 October 2021
Tubular epithelial NF-κB activity regulates ischemic AKI.
Markó, L., Vigolo, E., Hinze, C., Park, J.K., Roël, G., Balogh, A., Choi, M., Wübken, A., Cording, J., Blasig, I.E., Luft, F.C., Scheidereit, C., Schmidt-Ott, K.M., Schmidt-Ullrich, R. and Müller, D.N.
Journal of the American Society of Nephrology 27
(9): 2658-2669.
September 2016
The little skate genome and the evolutionary emergence of wing-like fins.
Marlétaz, F., de la Calle-Mustienes, E., Acemel, R.D., Paliou, C., Naranjo, S., Martínez-García, P.M., Cases, I., Sleight, V.A., Hirschberger, C., Marcet-Houben, M., Navon, D., Andrescavage, A., Skvortsova, K., Duckett, P.Ed., González-Rajal, Á., Bogdanovic, O., Gibcus, J.H., Yang, L., Gallardo-Fuentes, L., Sospedra, I., Lopez-Rios, J., Darbellay, F., Visel, A., Dekker, J., Shubin, N., Gabaldón, T., Nakamura, T., Tena, J.J., Lupianez, D.G., Rokhsar, D.S. and Gómez-Skarmeta, J.L.
Nature 616
(7957): 495-503.
20 April 2023
Identifying cancer cells from calling single-nucleotide variants in scRNA-seq data.
Marot-Lassauzaie, V., Beneyto-Calabuig, S., Obermayer, B., Velten, L., Beule, D. and Haghverdi, L.
Bioinformatics 40
(9): btae512.
September 2024
Towards reliable quantification of cell state velocities.
Marot-Lassauzaie, V., Bouman, B.J., Donaghy, F.D., Demerdash, Y., Essers, M.A.G. and Haghverdi, L.
PLoS Computational Biology 18
(9): e1010031.
28 September 2022
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1.
Marques, C., Unterkircher, T., Kroon, P., Oldrini, B., Izzo, A., Dramaretska, Y., Ferrarese, R., Kling, E., Schnell, O., Nelander, S., Wagner, E.F., Bakiri, L., Gargiulo, G., Carro, M.S. and Squatrito, M.
eLife 10
: e64846.
17 August 2021
A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21.
Martin, A.P., Coronel, E.C., Sano, G., Chen, S.C., Vassileva, G., Canasto-Chibuque, C., Sedgwick, J.D., Frenette, P.S., Lipp, M., Furtado, G.C. and Lira, S.A.
Journal of Immunology 173
(8): 4791-4798.
15 October 2004
Influence of corticosteroid treatment on CXCR4 expression in DLBCL.
Martin, S., Viertl, D., Janz, A., Habringer, S., Keller, U. and Schottelius, M.
EJNMMI Research 13
(1): 40.
10 May 2023
Induced recruitment of NK cells to lymph nodes provides IFN-gamma for TH1 priming.
Martin-Fontecha, A., Thomsen, L.L., Brett, S., Gerard, C., Lipp, M., Lanzavecchia, A. and Sallusto, F.
Nature Immunology 5
(12): 1260-1265.
1 January 2004
Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming.
Martin-Fontecha, A., Sebastiani, S., Höpken, U.E., Uguccioni, M., Lipp, M., Lanzavecchia, A. and Sallusto, F.
Journal of Experimental Medicine 198
(4): 615-621.
18 August 2003
CoBold: a method for identifying different functional classes of transient RNA structure features that can impact RNA structure formation in vivo.
Martín, A.L., Mounir, M. and Meyer, I.M.
Nucleic Acids Research 49
(4): e19.
26 February 2021
Genomic–transcriptomic evolution in lung cancer and metastasis.
Martínez-Ruiz, C., Black, J.R.M., Puttick, C., Hill, M.S., Demeulemeester, J., Larose Cadieux, E., Thol, K., Jones, T.P., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Prymas, P., Rowan, A., Ward, S., Cubitt, L., Athanasopoulou, F., Pich, O., Karasaki, T., Moore, D.A., Salgado, R., Colliver, E., Castignani, C., Dietzen, M., Huebner, A., Al Bakir, M., Tanić, M., Watkins, T.B.K., Lim, E.L., Al-Rashed, A.M., Lang, D., Clements, J., Cook, D.E., Rosenthal, R., Wilson, G. A., Frankell, A.M., de Carné Trécesson, S., East, P., Kanu, N., Litchfield, K., Birkbak, N.J., Hackshaw, A., Beck, S., Van Loo, P., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
(7957): 543-552.
20 April 2023
AP-1 imprints a reversible transcriptional programme of senescent cells.
Martínez-Zamudio, R.I., Roux, P.F., de Freitas, J.A.N.L.F., Robinson, L., Doré, G., Sun, B., Belenki, D., Milanovic, M., Herbig, U., Schmitt, C.A., Gil, J. and Bischof, O.
Nature Cell Biology 22
(7): 842-855.
July 2020
Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met.
Marx-Stoelting, P., Borowiak, M., Knorpp, T., Birchmeier, C., Buchmann, A. and Schwarz, M.
International Journal of Cancer 124
(8): 1767-1772.
15 April 2009
How branching can change the conductance of ballistic semiconductor devices.
Maryenko, D., Ospald, F., von Klitzing, K., Smet, J.H., Metzger, J.J., Fleischmann, R., Geisel, T. and Umansky, V.
Physical Review B 85
(19): 195329.
31 May 2012
A fraction of MCM 2 proteins remain associated with replication foci during a major part of S phase.
Masata, M., Juda, P., Raska, O., Cardoso, M.C. and Raska, I.
Folia Biologica Prague 57
(1): 3-11.
2011
Outcome analysis of 189 consecutive cancer patients referred to the intensive care unit as emergencies during a 2-year period.
Maschmeyer, G., Bertschat, F.L., Moesta, K.T., Haeusler, E., Held, T.K., Nolte, M., Osterziel, K.J., Papstein, V., Peters, M., Reich, G., Schmutzler, M., Sezer, O., Stula, M., Wauer, H., Woertz, T., Wischnewsky, M. and Hohenberger, P.
European Journal of Cancer 39
: 783-792.
1 April 2003
Nonmyeloablative stem cell transplantation in patients with ALL and AML results in low nonrelapse mortality despite high rate of infections and GVHD.
Massenkeil, G., Nagy, M., Le Coutre, P., Heine, F., Rosen, O., Doerken, B. and Arnold, R.
Hematology Journal 5
(5): 395-402.
1 January 2004
Survival after reduced-intensity conditioning is not inferior to standard high-dose conditioning before allogeneic haematopoietic cell transplantation in acute leukaemias.
Massenkeil, G., Nagy, M., Neuburger, S., Tamm, I., Lutz, C., Le Coutre, P., Rosen, O., Wernecke, K.D., Doerken, B. and Arnold, R.
Bone Marrow Transplantation 36
: 683-689.
22 August 2005
Nonmyeloablative stem cell transplantation in metastatic renal cell carcinoma: delayed graft-versus-tumor effect is associated with chimerism conversion but transplantation has high toxicity.
Massenkeil, G., Roigas, J., Nagy, M., Wille, A., Stroszczynski, C., Mapara, M.Y., Loening, S., Doerken, B. and Arnold, R.
Bone Marrow Transplantation 34
(4): 309-316.
1 August 2004
Frequent induction of chromosomal aberrations in in vivo skin fibroblasts after allogeneic stem cell transplantation: hints to chromosomal instability after irradiation.
Massenkeil, G., Zschieschang, P., Thiel, G., Hemmati, P.G., Budach, V., Doerken, B., Pross, J. and Arnold, R.
Radiation Oncology 10
: 266.
30 December 2015
Evolution of replication origins in vertebrate genomes: rapid turnover despite selective constraints.
Massip, F., Laurent, M., Brossas, C., Fernández-Justel, J.M., Gómez, M., Prioleau, M.N., Duret, L. and Picard, F.
Nucleic Acids Research 47
(10): 5114-5125.
4 June 2019
Targeting APLN/APLNR improves antiangiogenic efficiency and blunts proinvasive side effects of VEGFA/VEGFR2 blockade in glioblastoma.
Mastrella, G., Hou, M., Li, M., Stoecklein, V.M., Zdouc, N., Volmar, M.N.M., Miletic, H., Reinhard, S., Herold-Mende, C.C., Kleber, S., Eisenhut, K., Gargiulo, G., Synowitz, M., Vescovi, A.L., Harter, P.N., Penninger, J.M., Wagner, E., Mittelbronn, M., Bjerkvig, R., Hambardzumyan, D., Schüller, U., Tonn, J.C., Radke, J., Glass, R. and Kälin, R.E.
Cancer Research 79
(9): 2298-2313.
May 2019
Microglia development follows a stepwise program to regulate brain homeostasis.
Matcovitch-Natan, O., Winter, D.R., Giladi, A., Vargas Aguilar, S., Spinrad, A., Sarrazin, S., Ben-Yehuda, H., David, E., Zelada González, F., Perrin, P., Keren-Shaul, H., Gury, M., Lara-Astaiso, D., Thaiss, C.A., Cohen, M., Bahar Halpern, K., Baruch, K., Deczkowska, A., Lorenzo-Vivas, E., Itzkovitz, S., Elinav, E., Sieweke, M.H., Schwartz, M. and Amit, I.
Science 353
(6301): aad8670.
19 August 2016
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.
Mathas, S., Janz, M., Hummel, F., Hummel, M., Wollert-Wulf, B., Lusatis, S., Anagnostopoulos, I., Lietz, A., Sigvardsson, M., Jundt, F., Joehrens, K., Bommert, K., Stein, H. and Doerken, B.
Nature Immunology 7
(2): 207-215.
February 2006
Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S., Joehrens, K., Joos, S., Lietz, A., Hummel, F., Janz, M., Jundt, F., Anagnostopoulos, I., Bommert, K., Lichter, P., Stein, H., Scheidereit, C. and Doerken, B.
Blood 106
(13): 4287-4293.
25 August 2005
Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.
Mathas, S., Kreher, S., Meaburn, K.J., Joehrens, K., Lamprecht, B., Assaf, C., Sterry, W., Kadin, M.E., Daibata, M., Joos, S., Hummel, M., Stein, H., Janz, M., Anagnostopoulos, I., Schrock, E., Misteli, T. and Doerken, B.
Proceedings of the National Academy of Sciences of the United States of America 106
(14): 5831-5836.
7 April 2009
c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas, S., Lietz, A., Anagnostopoulos, I., Hummel, F., Wiesner, B., Janz, M., Jundt, F., Hirsch, B., Joehrens-Leder, K., Vornlocher, H.P., Bommert, K., Stein, H. and Doerken, B.
Journal of Experimental Medicine 199
(8): 1041-1052.
19 April 2004
Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S., Lietz, A., Janz, M., Hinz, M., Jundt, F., Scheidereit, C., Bommert, K. and Doerken, B.
Blood 102
(3): 1028-1034.
1 August 2003
Hodgkin lymphoma: pathology and biology.
Mathas, S., Hartmann, S. and Küppers, R.
Seminars in Hematology 53
(3): 139-147.
July 2016
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.
Mathas, S., Hinz, M., Anagnostopoulos, L., Krappmann, D., Lietz, A., Jundt, F., Bommert, K., Mechta-Grigoriou, F., Stein, H., Dörken, B. and Scheidereit, C.
EMBO Journal 21
(15): 4104-4113.
1 August 2002
Optimising urinary catecholamine metabolite diagnostics for neuroblastoma.
Matser, Y.A.H., Verly, I.R.N., van der Ham, M., de Sain‐van der Velden, M.G.M., Verhoeven‐Duif, N.M., Ash, S., Cangemi, G., Barco, S., Popovic, M.B., van Kuilenburg, A.B.P. and Tytgat, G.A.M.
Pediatric Blood and Cancer 70
(6): e30289.
June 2023
Despite the odds: formation of the SARS-CoV-2 methylation complex.
Matsuda, A., Plewka, J., Rawski, M., Mourão, A., Zajko, W., Siebenmorgen, T., Kresik, L., Lis, K., Jones, A.N., Pachota, M., Karim, A., Hartman, K., Nirwal, S., Sonani, R., Chykunova, Y., Minia, I., Mak, P., Landthaler, M., Nowotny, M., Dubin, G., Sattler, M., Suder, P., Popowicz, G.M., Pyrć, K. and Czarna, A.
Nucleic Acids Research 52
(11): 6441-6458.
24 June 2024
EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C., Lahmann, I., Kunz, S., Jonas, W., Melo, A.A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Blüher, M., Olschowski, H., Kompa, J., Brügger, B., Müller, D.N., Haucke, V., Schürmann, A., Birchmeier, C. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 117
(13): 7471-7481.
31 March 2020
eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization.
Matthaeus, C., Lian, X., Kunz, S., Lehmann, M., Zhong, C., Bernert, C., Lahmann, I., Müller, D.N., Gollasch, M. and Daumke, O.
PLoS ONE 14
(10): e0223620.
10 October 2019
Cellular pharmacology of the anti-hepatitis B virus agent beta-L-2',3'-didehydro-2',3'-dideoxy-N4-hydroxycytidine: relevance for activation in HepG2 cells.
Matthes, E. and Buenger, H.
Antimicrobial Agents and Chemotherapy 54
(1): 341-345.
16 January 2010
Strong and selective inhibitors of HBV-replication between novel N4-hydroxy-and 5-methyl-beta-L-deoxycytidine analogues.
Matthes, E., Funk, A., Krahn, I., Gaertner, K., von Janta-Lipinski, M., Lin, L., Will, H. and Sirma, H.
Antimicrobial Agents and Chemotherapy 51
(7): 2523-2530.
July 2007
Potent inhibitory activity of chimeric oligonucleotides targeting two different sites of human telomerase.
Matthes, E., Lehmann, C., Stulich, M., Wu, Y., Dimitrova, L., Uhlmann, E. and Janta-Lipinski, M.V.
Oligonucleotides 15
(4): 255-268.
December 2005
The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast ran binding protein 1 (Yrb1p).
Maurer, P., Redd, M., Solsbacher, J., Bischoff, F.R., Greiner, M., Podtelejnikov, A.V., Mann, M., Stade, K., Weis, K. and Schlenstedt, G.
Molecular Biology of the Cell 12
(3): 539-549.
March 2001
Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution.
Mauri, M., Kirchner, M., Aharoni, R., Ciolli Mattioli, C., van den Bruck, D., Gutkovitch, N., Modepalli, V., Selbach, M., Moran, Y. and Chekulaeva, M.
Nucleic Acids Research 45
(2): 938-950.
25 January 2017
Optimized Variants of the Cold Shock Protein from in Vitro Selection: Structural Basis of Their High Thermostability.
Max, K.E., Wunderlich, M., Roske, Y., Schmid, F.X. and Heinemann, U.
Journal of Molecular Biology 369
(4): 1087-1097.
15 June 2007
Common mode of DNA binding to cold shock domains: Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus.
Max, K.E., Zeeb, M., Bienert, R., Balbach, J. and Heinemann, U.
FEBS Journal 274
(5): 1265-1279.
March 2007
T-rich DNA single strands bind to a preformed site on the bacterial cold shock protein Bs-CspB.
Max, K.E.A., Zeeb, M., Bienert, R., Balbach, J. and Heinemann, U.
Journal of Molecular Biology 360
(3): 702-714.
14 July 2006
The relevance of the SH2 domain for c-Src functionality in triple-negative breast cancer cells.
Mayoral-Varo, V., Sánchez-Bailón, M.P., Calcabrini, A., García-Hernández, M., Frezza, V., Martín, M.E., González, V.M. and Martín-Pérez, J.
Cancers 13
(3): 462.
26 January 2021
The Lin28 cold-shock domain remodels pre-let-7 microRNA.
Mayr, F., Schütz, A., Dge, N. and Heinemann, U.
Nucleic Acids Research 40
(15): 7492-7506.
1 August 2012
Genome-wide identification and characterisation of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing.
Mazloomian, A. and Meyer, I.M.
RNA Biology 12
(12): 1391-1401.
December 2015
Structure-based mapping of the histone-binding pocket of KDM4D using functionalized tetrazole and pyridine core compounds.
Małecki, P.H., Fassauer, G.M., Rüger, N., Schulig, L., Link, A., Krylova, O., Heinemann, U. and Weiss, M.S.
European Journal of Medicinal Chemistry 276
: 116642.
5 October 2024
In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes.
McCann, M., Santos, A.L.S., da Silva, B.A., Romanos, M.T.V., Pyrrho, A.S., Devereux, M., Kavanagh, K., Fichtner, I. and Kellett, A.
Toxicology Research 1
(1): 47-54.
July 2012
A gene expression atlas of embryonic neurogenesis in Drosophila reveals complex spatiotemporal regulation of lncRNAs.
McCorkindale, A.L., Wahle, P., Werner, S., Jungreis, I., Menzel, P., Shukla, C.J., Abreu, R.L.P., Irizarry, R.A., Meyer, I.M., Kellis, M. and Zinzen, R.P.
Development 146
(6): dev175265.
28 March 2019
Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
McGarvey, A.C., Kopp, W., Vučićević, D., Mattonet, K., Kempfer, R., Hirsekorn, A., Bilić, I., Gil, M., Trinks, A., Merks, A.M., Panáková, D., Pombo, A., Akalin, A., Junker, J.P., Stainier, D.Y.R., Garfield, D., Ohler, U. and Lacadie, S.A.
Cell Genomics 2
(1): 100083.
13 January 2022
The transcriptional landscape of hematopoietic stem cell ontogeny.
McKinney-Freeman, S., Cahan, P., Li, H., Lacadie, S.A., Huang, H.T., Curran, M., Loewer, S., Naveiras, O., Kathrein, K.L., Konantz, M., Langdon, E.M., Lengerke, C., Zon, L.I., Collins, J.J. and Daley, G.Q.
Cell Stem Cell 11
(5): 701-714.
2 November 2012
Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.
McNeill, B., Perez-Iratxeta, C., Mazerolle, C., Furimsky, M., Mishina, Y., Andrade-Navarro, M.A. and Wallace, V.A.
Molecular and Cellular Neuroscience 49
(3): 333-340.
March 2012
CD8alpha/alpha homodimers fail to function as co-receptor for a CD8-dependent TCR.
McNicol, A.M., Bendle, G., Holler, A., Matjeka, T., Dalton, E., Rettig, L., Zamoyska, R., Uckert, W., Xue, S.A. and Stauss, H.J.
European Journal of Immunology 37
(6): 1634-1641.
June 2007
RAGE mediates the pro-migratory response of extracellular S100A4 in human thyroid cancer cells.
Medapati, M.R., Dahlmann, M., Ghavami, S., Pathak, K.A., Lucman, L., Klonisch, T., Hoang-Vu, C., Stein, U. and Hombach-Klonisch, S.
Thyroid 25
(5): 514-527.
4 May 2015
A transcription factor affinity-based code for mammalian transcription initiation.
Megraw, M., Pereira, F., Jensen, S.T., Ohler, U. and Hatzigeorgiou, A.G.
Genome Research 19
(4): 644-656.
April 2009
Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane.
Mehnert, M., Sommer, T. and Jarosch, E.
Nature Cell Biology 16
(1): 77-86.
January 2014
The interplay of Hrd3 and the molecular chaperone system ensures efficient degradation of malfolded secretory proteins.
Mehnert, M., Sommermeyer, F., Berger, M., Lakshmipathy, S.K., Gauss, R., Aebi, M., Jarosch, E. and Sommer, T.
Molecular Biology of the Cell 26
(2): 185-194.
15 January 2015
Structure-activity relationship study of dendritic polyglycerolamines for efficient siRNA transfection.
Mehrabadi, F.S., Hirsch, O., Zeisig, R., Posocco, P., Laurini, E., Pricl, S., Haag, R., Kemmner, W. and Calderon, M.
RSC Advances 5
(96): 78760-78770.
8 September 2015
FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.
Meier, F., Giesert, F., Delic, S., Faus-Kessler, T., Matheus, F., Simeone, A., Hoelter, S.M., Kühn, R., Vogt-Weisenhorn, D.M., Wurst, W. and Prakash, N.
PLoS ONE 9
(7): e101124.
1 July 2014
Structural stability and dynamics of hydrogenated and perdeuterated cytochrome P450cam (CYP101).
Meilleur, F., Contzen, J., Myles, D.A. and Jung, C.
Biochemistry 43
(27): 8744-8753.
13 July 2004
Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T., Lindemann, P., Welle, A., Trouillet, V., Heißler, S., Nazaré, M. and Selbach, M.
ChemMedChem 17
(19): e202200346.
6 October 2022
Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Melo, A.A., Hegde, B.G., Shah, C., Larsson, E., Isas, J.M., Kunz, S., Lundmark, R., Langen, R. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 114
(22): 5629-5634.
30 May 2017
Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A., Sprink, T., Noel, J.K., Vázquez-Sarandeses, E., van Hoorn, C., Mohd, S., Loerke, J., Spahn, C.M.T. and Daumke, O.
Nature Communications 13
(1): 7641.
10 December 2022
Distinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets.
Menning, A., Höpken, U.E., Siegmund, K., Lipp, M., Hamann, A. and Huehn, J.
European Journal of Immunology 37
(6): 1575-1583.
June 2007
CD3 aptamers promote expansion and persistence of tumor-reactive T cells for adoptive T cell therapy in cancer.
Menon, A.P., Villanueva, H., Meraviglia-Crivelli, D., van Santen, H.M., Hellmeier, J., Zheleva, A., Nonateli, F., Peters, T., Wachsmann, T.L.A., Hernandez-Rueda, M., Huppa, J.B., Schütz, G.J., Sevcsik, E., Moreno, B. and Pastor, F.
Molecular Therapy Nucleic Acids 35
(2): 102198.
11 June 2024
Human induced pluripotent stem cell-derived pericytes as scalable and editable source to study direct lineage reprogramming into induced neurons.
Menon, R., Petrucci, L., Lohrer, B., Zhang, J., Schulze, M., Schichor, C., Winner, B., Winkler, J., Riemenschneider, M.J., Kühn, R., Falk, S. and Karow, M.
Cellular Reprogramming 25
(5): 212-223.
13 October 2023
Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA.
Mensali, N., Ying, F., Sheng, V.O.Y., Yang, W., Walseng, E., Kumari, S., Fallang, L.E., Kolstad, A., Uckert, W., Malmberg, K.J., Waelchli, S. and Olweus, J.
OncoImmunology 5
(5): e1138199.
18 February 2016
Altered B-cell subsets and functional B-cell defects in selective IgM deficiency.
Mensen, A., Krause, T., Hanitsch, L.G., Meisel, C., Kleint, M.E., Volk, H.D., Na, I.K. and Scheibenbogen, C.
Clinical Immunology 161
(2): 96-102.
December 2015
Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT.
Mensen, A., Jöhrens, K., Anagnostopoulos, I., Demski, S., Oey, M., Stroux, A., Hemmati, P., Westermann, J., Blau, O., Wittenbecher, F., Movassaghi, K., Szyska, M., Thomas, S., Dörken, B., Scheibenbogen, C., Arnold, R. and Na, I.K.
Blood 124
(6): 963-972.
7 August 2014
Comparison of different rabbit ATG preparation effects on early lymphocyte subset recovery after allogeneic HSCT and its association with EBV-mediated PTLD.
Mensen, A., Na, I.K., Häfer, R., Meerbach, A., Schlecht, M., Pietschmann, M.L. and Gruhn, B.
Journal of Cancer Research and Clinical Oncology 140
(11): 1971-1980.
November 2014
Utilization of TREC and KREC quantification for the monitoring of early T- and B-cell neogenesis in adult patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A., Ochs, C., Stroux, A., Wittenbecher, F., Szyska, M., Imberti, L., Fillatreau, S., Uharek, L., Arnold, R., Dörken, B., Thiel, A., Scheibenbogen, C. and Na, I.K.
Journal of Translational Medicine 11
(1): 188.
14 August 2013
Apoptosis-susceptibility prolongs the lack of memory B cells in acute leukemic patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A., Oh, Y., Becker, S.C., Hemmati, P.G., Jehn, C., Westermann, J., Szyska, M., Göldner, H., Dörken, B., Scheibenbogen, C., Arnold, R. and Na, I.K.
Biology of Blood and Marrow Transplantation 21
(11): 1895-1906.
November 2015
Lymphocyte access to lymphoma is impaired by high endothelial venule regression.
Menzel, L., Zschummel, M., Crowley, T., Franke, V., Grau, M., Ulbricht, C., Hauser, A., Siffrin, V., Bajénoff, M., Acton, S.E., Akalin, A., Lenz, G., Willimsky, G., Höpken, U.E. and Rehm, A.
Cell Reports 37
(4): 109878.
26 October 2021
Analyses of murine lymph node endothelial cell subsets using single-cell RNA sequencing and spectral flow cytometry.
Menzel, L., Zschummel, M. and Rehm, A.
STAR Protocols 3
(2): 101267.
17 June 2022
Transcriptional dynamics of microRNAs and their targets during Drosophila neurogenesis.
Menzel, P., McCorkindale, A.L., Stefanov, S.R., Zinzen, R.P. and Meyer, I.M.
RNA Biology 16
(1): 69-81.
20 January 2019
A novel approach for protein subcellular location prediction using amino acid exposure.
Mer, A.S. and Andrade-Navarro, M.A.
BMC Bioinformatics 14
(1): 342.
28 November 2013
A high-resolution map of small-scale inversions in the gibbon genome.
Mercuri, L., Palmisano, D., L'Abbate, A., D'Addabbo, P., Montinaro, F., Catacchio, C.R., Hasenfeld, P., Ventura, M., Korbel, J.O., Sanders, A.D., Maggiolini, F.A.M. and Antonacci, F.
Genome Research 32
(10): 1941-1951.
October 2022
Patient-derived xenografts of non-small-cell lung cancer: a pre-clinical model to evaluate adjuvant chemotherapy?
Merk, J., Rolff, J., Becker, M., Leschber, G. and Fichtner, I.
European Journal of Cardio-Thoracic Surgery 36
(3): 454-459.
September 2009
Chemoresistance in non-small-cell lung cancer: can multidrug resistance markers predict the response of xenograft lung cancer models to chemotherapy?
Merk, J., Rolff, J., Dorn, C., Leschber, G. and Fichtner, I.
European Journal of Cardio-Thoracic Surgery 40
(1): e29-e33.
July 2011
Interleukin-9 (IL-9) and NPM-ALK each generate mast cell hyperplasia as single 'hit' and cooperate in producing a mastocytosis-like disease in mice.
Merz, H., Kaehler, C., Hoefig, K.P., Branke, B., Uckert, W., Nadrowitz, R., Cerny-Reiterer, S., Herrmann, H., Feller, A.C. and Valent, P.
Oncotarget 1
(2): 104-119.
7 June 2010
Die Ueberexpression von NPM-ALK in haematopoietischen Stammzellen induziert verschiedene maligne Non-Hodgkin-Lymphome in der IL-9 transgenen Maus [Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice].
Merz, H., Lange, K., Nadrowitz, R., Uckert, W., Blankenstein, T. and Feller, A.C.
Verhandlungen der Deutschen Gesellschaft fuer Pathologie 87
: 224-231.
1 January 2003
The inner membrane protein Mdm33 controls mitochondrial morphology in yeast.
Messerschmitt, M., Jakobs, S., Vogel, F., Fritz, S., Dimmer, K.S., Neupert, W. and Westermann, B.
Journal of Cell Biology 160
(4): 553-564.
18 February 2003
Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes.
Metsuyanim, S., Pode-Shakked, N., Schmidt-Ott, K.M., Keshet, G., Rechavi, G., Blumental, D. and Dekel, B.
Stem Cells 26
(7): 1808-1817.
July 2008
A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants.
Metzdorf, K., Jacobsen, H., Kim, Y., Teixeira Alves, L.G., Kulkarni, U., Brdovčak, M.C., Materljan, J., Eschke, K., Chaudhry, M.Z., Hoffmann, M., Bertoglio, F., Ruschig, M., Hust, M., Šustić, M., Krmpotić, A., Jonjić, S., Widera, M., Ciesek, S., Pöhlmann, S., Landthaler, M. and Čičin-Šain, L.
Frontiers in Immunology 15
: 1383086.
25 July 2024
Distribution of the fittest individuals and the rate of Muller's ratchet in a model with overlapping generations.
Metzger, J.J. and Eule, S.
PLoS Computational Biology 9
(11): e1003303.
November 2013
Statistics of extreme waves in random media.
Metzger, J.J., Fleischmann, R. and Geisel, T.
Physical Review Letters 112
(20): 203903.
23 May 2014
Intensity fluctuations of waves in random media: what is the semiclassical limit?
Metzger, J.J., Fleischmann, R. and Geisel, T.
Physical Review Letters 111
(1): 013901.
5 July 2013
Universal statistics of branched flows.
Metzger, J.J., Fleischmann, R. and Geisel, T.
Physical Review Letters 105
(2): 020601.
9 July 2010
Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models.
Metzger, J.J., Pereda, C., Adhikari, A., Haremaki, T., Galgoczi, S., Siggia, E.D., Brivanlou, A.H. and Etoc, F.
Cell Reports Methods 2
(9): 100297.
19 September 2022
Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation.
Meusser, B. and Sommer, T.
Molecular Cell 14
(2): 247-258.
1 January 2004
Gene structure conservation aids similarity based gene prediction.
Meyer, I.M. and Durbin, R.
Nucleic Acids Research 32
(2): 776-783.
4 February 2004
Comparative ab initio prediction of gene structures using pair HMMs.
Meyer, I.M. and Durbin, R.
Bioinformatics 18
(10): 1309-1318.
October 2002
SimulFold: simultaneously inferring RNA structures including pseudoknots, alignments, and trees using a Bayesian MCMC framework.
Meyer, I.M. and Miklos, I.
PLoS Computational Biology 3
(8): e149.
10 August 2007
Statistical evidence for conserved, local secondary structure in the coding regions of eukaryotic mRNAs and pre-mRNAs.
Meyer, I.M. and Miklos, I.
Nucleic Acids Research 33
(19): 6338-6348.
7 November 2005
Co-transcriptional folding is encoded within RNA genes.
Meyer, I.M. and Miklos, I.
BMC Molecular Biology 5
: 10.
6 August 2004
Transformation and additional malignancies are leading risk factors for an adverse course of disease in marginal zone lymphoma.
Meyer, A.H., Stroux, A., Lerch, K., Eucker, J., Eitle, J., Hohloch, K., Andrzejak, M., Possinger, K., Dörken, B., Pezzutto, A. and Scholz, C.W.
Annals of Oncology 25
(1): 210-215.
January 2014
In silico methods for co-transcriptional RNA secondary structure prediction and for investigating alternative RNA structure expression.
Meyer, I.M.
Methods 120
: 3-16.
1 May 2017
Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K., Kirchner, M., Uyar, B., Cheng, J.Y., Russo, G., Hernandez-Miranda, L.R., Szymborska, A., Zauber, H., Rudolph, I.M., Willnow, T.E., Akalin, A., Haucke, V., Gerhardt, H., Birchmeier, C., Kühn, R., Krauss, M., Diecke, S., Pascual, J.M. and Selbach, M.
Cell 175
(1): 239-253.
20 September 2018
Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1).
Meyer, T., Jahn, N., Lindner, S., Röhner, L., Dolnik, A., Weber, D., Scheffold, A., Köpff, S., Paschka, P., Gaidzik, V.I., Heckl, D., Wiese, S., Ebert, B.L., Döhner, H., Bullinger, L., Döhner, K. and Krönke, J.
Leukemia 34
(2): 404-415.
February 2020
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt, L., Braun, J., Fauchere, F., Vanshylla, K., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Jürchott, K., Mangold, M., Maraj, A., Braginets, A., Böttcher, C., Nitsche, A., de la Rosa, K., Ratswohl, C., Sawitzki, B., Holenya, P., Reimer, U., Sander, L.E., Klein, F., Paul, F., Bellmann-Strobl, J., Thiel, A. and Giesecke-Thiel, C.
Journal of Neurology Neurosurgery and Psychiatry 93
(9): 960-971.
September 2022
Targeting the epidermal growth factor receptor (HER) family by T cell receptor gene-modified T lymphocytes.
Meyerhuber, P., Conrad, H., Staerck, L., Leisegang, M., Busch, D.H., Uckert, W. and Bernhard, H.
Journal of Molecular Medicine 88
(11): 1113-1121.
November 2010
Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo.
Michaelis, M., Fichtner, I., Behrens, D., Haider, W., Rothweiler, F., Mack, A., Cinatl, J., Doerr, H.W. and Cinatl, J.
International Journal of Oncology 28
(2): 439-446.
February 2006
Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins.
Michaelis, M., Bliss, J., Arnold, S.C., Hinsch, N., Rothweiler, F., Deubzer, H.E., Witt, O., Langer, K., Doerr, H.W., Wels, W.S. and Cinatl, J.
Clinical Cancer Research 14
(20): 6531-6537.
16 October 2008
Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.
Michaelis, M., Kleinschmidt, M.C., Barth, S., Rothweiler, F., Geiler, J., Breitling, R., Mayer, B., Deubzer, H., Witt, O., Kreuter, J., Doerr, H.W., Cinatl, J. and Cinatl, J.
Biochemical Pharmacology 79
(2): 130-136.
15 January 2010
Eukaryotic initiation factor 2α phosphorylation is required for B cell maturation and function in mice.
Mielke, N., Schwarzer, R., Calkhoven, C.F., Kaufman, R., Doerken, B., Leutz, A. and Jundt, F.
Haematologica 96
(9): 1261-1268.
September 2011
A linear memory algorithm for Baum-Welch training.
Miklos, I. and Meyer, I.M.
BMC Bioinformatics 6
: 231.
19 September 2005
Moments of the Boltzmann distribution for RNA secondary structures.
Miklos, I., Meyer, I.M. and Nagy, B.
Bulletin of Mathematical Biology 67
(5): 1031-1047.
September 2005
Inferring time series chromatin states for promoter-enhancer pairs based on Hi-C data.
Miko, H., Qiu, Y., Gaertner, B., Sander, M. and Ohler, U.
BMC Genomics 22
(1): 84.
28 January 2021
The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N., Kolesnichenko, M., Beaudette, P., Popp, O., Uyar, B., Sun, W., Tufan, A.B., Perder, B., Akalin, A., Chen, W., Mertins, P., Dittmar, G., Hinz, M. and Scheidereit, C.
EMBO Journal 37
(24): e98658.
14 December 2018
Deficiency in IκBα in the intestinal epithelium leads to spontaneous inflammation and mediates apoptosis in the gut.
Mikuda, N., Schmidt-Ullrich, R., Kärgel, E., Golusda, L., Wolf, J., Höpken, U.E., Scheidereit, C., Kühl, A.A. and Kolesnichenko, M.
Journal of Pathology 251
(2): 160-174.
June 2020
Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M., Fan, D.N.Y., Belenki, D., Däbritz, J.H.M., Zhao, Z., Yu, Y., Dörr, J.R., Dimitrova, L., Lenze, D., Monteiro Barbosa, I.A., Mendoza-Parra, M.A., Kanashova, T., Metzner, M., Pardon, K., Reimann, M., Trumpp, A., Dörken, B., Zuber, J., Gronemeyer, H., Hummel, M., Dittmar, G., Lee, S. and Schmitt, C.A.
Nature 553
(7686): 96-100.
4 January 2018
Nestin expression identifies ependymoma patients with poor outcome.
Milde, T., Hielscher, T., Witt, H., Kool, M., Mack, S.C., Deubzer, H.E., Oehme, I., Lodrini, M., Benner, A., Taylor, M.D., von Deimling, A., Kulozik, A.E., Pfister, S.M., Witt, O. and Korshunov, A.
Brain Pathology 22
(6): 848-860.
November 2012
A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
Milde, T., Kleber, S., Korshunov, A., Witt, H., Hielscher, T., Koch, P., Kopp, H.G., Jugold, M., Deubzer, H.E., Oehme, I., Lodrini, M., Gröne, H.J., Benner, A., Brüstle, O., Gilbertson, R.J., von Deimling, A., Kulozik, A.E., Pfister, S.M., Martin-Villalba, A. and Witt, O.
Acta Neuropathologica 122
(5): 637-650.
November 2011
HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.
Milde, T., Lodrini, M., Savelyeva, L., Korshunov, A., Kool, M., Brueckner, L.M., Antunes, A.S.L.M., Oehme, I., Pekrun, A., Pfister, S.M., Kulozik, A.E., Witt, O. and Deubzer, H.E.
Journal of Neuro-Oncology 110
(3): 335-348.
December 2012
HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth.
Milde, T., Oehme, I., Korshunov, A., Kopp-Schneider, A., Remke, M., Northcott, P., Deubzer, H.E., Lodrini, M., Taylor, M.D., von Deimling, A., Pfister, S. and Witt, O.
Clinical Cancer Research 16
(12): 3240-3252.
15 June 2010
Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma.
Milde, T., Pfister, S., Korshunov, K., Deubzer, H.E., Oehme, I., Ernst, A., Starzinski-Powitz, A., Seitz, A., Lichter, P., von Deimling, A. and Witt, O.
Genes Chromosomes & Cancer 48
(3): 229-238.
March 2009
Genomic characterization of murine monocytes reveals C/EBPβ transcription factor dependence of Ly6C(-) cells.
Mildner, A., Schönheit, J., Giladi, A., David, E., Lara-Astiaso, D., Lorenzo-Vivas, E., Paul, F., Chappell-Maor, L., Priller, J., Leutz, A., Amit, I. and Jung, S.
Immunity 46
(5): 849-862.
16 May 2017
DDX54 regulates transcriptome dynamics during DNA damage response.
Milek, M., Imami, K., Mukherjee, N., De Bortoli, F., Zinnall, U., Hazapis, O., Trahan, C., Oeffinger, M., Heyd, F., Ohler, U., Selbach, M. and Landthaler, M.
Genome Research 27
(8): 1344-1359.
August 2017
Systematic detection of poly(A)(+) RNA-interacting proteins and their differential binding.
Milek, M. and Landthaler, M.
Methods in Molecular Biology 1649
: 405-417.
2018
Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence.
Miller, D.C., Lisowski, P., Genehr, C., Wanker, E.E., Priller, J., Prigione, A. and Diecke, S.
Stem Cell Research 68
: 103056.
April 2023
Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C., Lisowski, P., Lickfett, S., Mlody, B., Bünning, M., Genehr, C., Ulrich, C., Wanker, E.E., Diecke, S., Priller, J. and Prigione, A.
Stem Cell Research 65
: 102976.
December 2022
Tumor-infiltrating merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival.
Miller, N.J., Church, C.D., Dong, L., Crispin, D., Fitzgibbon, M.P., Lachance, K., Jing, L., Shinohara, M., Gavvovidis, I., Willimsky, G., McIntosh, M., Blankenstein, T., Koelle, D.M. and Nghiem, P.
Cancer Immunology Research 5
(2): 137-147.
February 2017
p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.
Milojkovic, A., Hemmati, P.G., Mueer, A., Overkamp, T., Chumduri, C., Jaenicke, R.U., Gillissen, B. and Daniel, P.T.
International Journal of Cancer 133
(11): 2551-2562.
1 December 2013
Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Mimitou, E.P., Lareau, C.A., Chen, K.Y., Zorzetto-Fernandes, A.L., Hao, Y., Takeshima, Y., Luo, W., Huang, T.S., Yeung, B.Z., Papalexi, E., Thakore, P.I., Kibayashi, T., Wing, J.B., Hata, M., Satija, R., Nazor, K.L., Sakaguchi, S., Ludwig, L.S., Sankaran, V.G., Regev, A. and Smibert, P.
Nature Biotechnology 39
(10): 1246-1258.
October 2021
Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Ming, Q., Roske, Y., Schuetz, A., Walentin, K., Ibraimi, I., Schmidt-Ott, K.M. and Heinemann, U.
Nucleic Acids Research 46
(4): 2082-2095.
28 February 2018
Regnase-1 and roquin regulate a common element in inflammatory mRNAs by spatiotemporally distinct mechanisms.
Mino, T., Murakawa, Y., Fukao, A., Vandenbon, A., Wessels, H.H., Ori, D., Uehata, T., Tartey, S., Akira, S., Suzuki, Y., Vinuesa, C.G., Ohler, U., Standley, D.M., Landthaler, M., Fujiwara, T. and Takeuchi, O.
Cell 161
(5): 1058-1073.
21 May 2015
Small molecules co-targeting CKIα and the transcriptional kinases CDK7/9 control AML in preclinical models.
Minzel, W., Venkatachalam, A., Fink, A., Hung, E., Brachya, G., Burstain, I., Shaham, M., Rivlin, A., Omer, I., Zinger, A., Elias, S., Winter, E., Erdman, P.E., Sullivan, R.W., Fung, L., Mercurio, F., Li, D., Vacca, J., Kaushansky, N., Shlush, L., Oren, M., Levine, R., Pikarsky, E., Snir-Alkalay, I. and Ben-Neriah, Y.
Cell 175
(1): 171-185.e25.
20 September 2018
Transcriptional regulation of the murine urokinase-type plasminogen activator gene in skeletal myoblasts.
Miralles, F., Ibanez-Tallon, I., Parra, M., Crippa, M., Blasi, F., Besser, D., Nagamine, Y. and Munoz-Canoves, P.
Thrombosis and Haemostasis 81
(5): 767-774.
May 1999
Novel pathogenic mechanisms of congenital insensitivity to pain with anhidrosis genetic disorder unveiled by functional analysis of neurotrophic tyrosine receptor kinase type 1/nerve growth factor receptor mutations.
Miranda, C., Di Virgilio, M., Selleri, S., Zanotti, G., Pagliardini, S., Pierotti, M.A. and Greco, A.
Journal of Biological Chemistry 277
(8): 6455-6462.
22 February 2002
CRISPR/Cas9 screen in gastric cancer patient-derived organoids reveals KDM1A-NDRG1 axis as a targetable vulnerability.
Mircetic, J., Camgöz, A., Abohawya, M., Ding, L., Dietzel, J., Tobar, S.G., Paszkowski-Rogacz, M., Seidlitz, T., Schmäche, T., Mehnert, M.C., Sidorova, O., Weitz, J., Buchholz, F. and Stange, D.E.
Small Methods 7
(6): e2201605.
20 June 2023
Estrogen-related receptor alpha modulates lactate dehydrogenase activity in thyroid tumors.
Mirebeau-Prunier, D., Le Pennec, S., Jacques, C., Fontaine, J.F., Gueguen, N., Boutet-Bouzamondo, N., Donnart, A., Malthiery, Y. and Savagner, F.
PLoS ONE 8
(3): e58683.
13 March 2013
Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.
Mirski, S.E.L., Sparks, K.E., Friedrich, B., Koehler, M., Mo, Y.Y., Beck, W.T. and Cole, S.P.C.
Experimental Cell Research 313
(3): 627-637.
1 February 2007
The Frog Prince: a reconstructed transposon from Rana pipiens with high transpositional activity in vertebrate cells.
Miskey, C., Izsvak, Z., Plasterk, R.H. and Ivics, Z.
Nucleic Acids Research 31
(23): 6873-6881.
1 December 2003
The Ancient Mariner Sails Again: Transposition of the Human Hsmar1 Element by a Reconstructed Transposase and Activities of the SETMAR Protein on Transposon Ends.
Miskey, C., Papp, B., Mates, L., Sinzelle, L., Keller, H., Izsvak, Z. and Ivics, Z.
Molecular and Cellular Biology 27
(12): 4589-4600.
15 June 2007
The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.
Mistry, A.C., Mallick, R., Froehlich, O., Klein, J.D., Rehm, A., Chen, G. and Sands, J.M.
Journal of Biological Chemistry 282
(41): 30097-30106.
12 October 2007
Suicide nanoplasmids coding for ribosome-inactivating proteins.
Mitdank, H., Tröger, M., Sonntag, A., Shirazi, N.A., Woith, E., Fuchs, H., Kobelt, D., Walther, W. and Weng, A.
European Journal of Pharmaceutical Sciences 170
: 106107.
1 March 2022
Dissecting the spatiotemporal diversity of adult neural stem cells.
Mitic, N., Neuschulz, A., Spanjaard, B., Schneider, J., Fresmann, N., Novoselc, K.T., Strunk, T., Münster, L., Olivares-Chauvet, P., Ninkovic, J. and Junker, J.P.
Molecular Systems Biology 20
(4): 321-337.
2 April 2024
Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy.
Mitra, D., Vega-Rubin-de-Celis, S., Royla, N., Bernhardt, S., Wilhelm, H., Tarade, N., Poschet, G., Buettner, M., Binenbaum, I., Borgoni, S., Vetter, M., Kantelhardt, E.J., Thomssen, C., Chatziioannou, A., Hell, R., Kempa, S., Müller-Decker, K. and Wiemann, S.
International Journal of Cancer 148
(8): 1993-2009.
15 April 2021
Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domain.
Mo, X., Kowenz-Leutz, E., Laumonnier, Y., Xu, H. and Leutz, A.
Genes & Development 19
(20): 2447-2457.
29 September 2005
Ras induces mediator complex exchange on C/EBPβ.
Mo, X.M., Kowenz-Leutz, E., Xu, H. and Leutz, A.
Molecular Cell 13
(2): 241-250.
30 January 2004
Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia.
Mochmann, L.H., Treue, D., Bockmayr, M., Silva, P., Zasada, C., Mastrobuoni, G., Bayram, S., Forbes, M., Jurmeister, P., Liebig, S., Blau, O., Schleich, K., Splettstoesser, B., Nordmann, T.M., von der Heide, E.K., Isaakidis, K., Schulze, V., Busch, C., Siddiq, H., Schlee, C., Hester, S., Fransecky, L., Neumann, M., Kempa, S., Klauschen, F. and Baldus, C.D.
Cancer Gene Therapy 31
(9): 1344-1356.
September 2024
S3-Leitlinie "Magenkarzinom" - Diagnostik und Therapie der Adenokarzinome des Magens und oesophagogastralen Uebergangs (AWMF-Regist.-Nr. 032-009-OL) [German S3-Guideline "Diagnosis and Treatment of Esophagogastric Cancer"].
Moehler, M., Al-Batran, S.E., Andus, T., Anthuber, M., Arends, J., Arnold, D., Aust, D., Baier, P., Baretton, G., Bernhardt, J., Boeing, H., Boehle, E., Bokemeyer, C., Bornschein, J., Budach, W., Burmester, E., Caca, K., Diemer, W.A., Dietrich, C.F., Ebert, M., Eickhoff, A., Ell, C., Fahlke, J., Feußner, H., Fietkau, R., Fischbach, W., Fleig, W., Flentje, M., Gabbert, H.E., Galle, P.R., Geissler, M., Gockel, I., Graeven, U., Grenacher, L., Gross, S., Hartmann, J.T., Heike, M., Heinemann, V., Herbst, B., Herrmann, T., Hoecht, S., Hofheinz, R.D., Hoefler, H., Hoehler, T., Hoelscher, A.H., Horneber, M., Huebner, J., Izbicki, J.R., Jakobs, R., Jenssen, C., Kanzler, S., Keller, M., Kiesslich, R., Klautke, G., Körber, J., Krause, B.J., Kuhn, C., Kullmann, F., Lang, H., Link, H., Lordick, F., Ludwig, K., Lutz, M., Mahlberg, R., Malfertheiner, P., Merkel, S., Messmann, H., Meyer, H.J., Moenig, S., Piso, P., Pistorius, S., Porschen, R., Rabenstein, T., Reichardt, P., Ridwelski, K., Roecken, C., Roetzer, I., Rohr, P., Schepp, W., Schlag, P.M., Schmid, R.M., Schmidberger, H., Schmiegel, W.H., Schmoll, H.J., Schuch, G., Schuhmacher, C., Schuette, K., Schwenk, W., Selgrad, M., Sendler, A., Seraphin, J., Seufferlein, T., Stahl, M., Stein, H., Stoll, C., Stuschke, M., Tannapfel, A., Tholen, R., Thuss-Patience, P., Treml, K., Vanhoefer, U., Vieth, M., Vogelsang, H., Wagner, D., Wedding, U., Weimann, A., Wilke, H. and Wittekind, C.
Zeitschrift fuer Gastroenterologie 49
(4): 461-531.
April 2011
Diversin regulates heart formation and gastrulation movements in development.
Moeller, H., Jenny, A., Schaeffer, H.J., Schwarz-Romond, T., Mlodzik, M., Hammerschmidt, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 103
(43): 15900-15905.
24 October 2006
The Helicobacter pylori CagA protein disrupts matrix adhesion of gastric epithelial cells by dephosphorylation of vinculin.
Moese, S., Selbach, M., Brinkmann, V., Karlas, A., Haimovich, B., Backert, S. and Meyer, T.F.
Cellular Microbiology 9
(5): 1148-1161.
May 2007
Therapieverfahren fuer Adenokarzinome des oesophagogastralen Uebergangs [Treatment procedures for adenocarcinoma of the esophagogastric junction].
Moesta, K.T., Huenerbein, M. and Schlag, P.M.
Chirurg 74
(4): 381-393.
April 2003
Lack of reciprocity in drug and light dose dependence of photodynamic therapy of pancreatic adenocarcinoma in vitro.
Moesta, K.T., Greco, W.R., Nurse-Finlay, S.O., Parsons, J.C. and Mang, T.S.
Cancer Research 55
(14): 3078-3084.
15 July 1995
The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning.
Mohan, M., Bartkuhn, M., Herold, M., Philippen, A., Heinl, N., Bardenhagen, I., Leers, J., White, R.A.H., Renkawitz-Pohl, R., Saumweber, H. and Renkawitz, R.
EMBO Journal 26
(19): 4203-4214.
3 October 2007
Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model.
Mohan, A.M., Prasad, S., Schmitz-Peiffer, F., Lange, C., Lukas, M., Koziolek, E.J., Albrecht, J., Messroghli, D., Stein, U., Ilmer, M., Wang, K., Schober, L., Reul, A., Maurer, J., Friemel, J., Weber, A., Zuellig, R.A., Hantel, C., Fritsch, R., Reincke, M., Pacak, K., Grossman, A.B., Auernhammer, C.J., Beuschlein, F., Brenner, W., Beindorff, N. and Nölting, S.
Endocrine-Related Cancer 31
(1): e230041.
January 2024
Identification of drug-like molecules targeting the ATPase activity of dynamin-like EHD4.
Mohd, S., Oder, A., Specker, E., Neuenschwander, M., von Kries, J.P. and Daumke, O.
PLoS ONE 19
(7): e0302704.
29 July 2024
The cell fate determinant Scribble is required for maintenance of hematopoietic stem cell function.
Mohr, J., Dash, B.P., Schnoeder, T.M., Wolleschak, D., Herzog, C., Tubio Santamaria, N., Weinert, S., Godavarthy, S., Zanetti, C., Naumann, M., Hartleben, B., Huber, T.B., Krause, D.S., Kähne, T., Bullinger, L. and Heidel, F.H.
Leukemia 32
(5): 1211-1221.
May 2018
Effects of anti-C5a monoclonal antibodies on oxygen use in a porcine model of severe sepsis.
Mohr, M., Höpken, U., Oppermann, M., Mathes, C., Goldmann, K., Siever, S., Goetze, O. and Burchardi, H.
European Journal of Clinical Investigation 28
(3): 227-234.
March 1998
Decoding the regulatory network of early blood development from single-cell gene expression measurements.
Moignard, V., Woodhouse, S., Haghverdi, L., Lilly, A.J., Tanaka, Y., Wilkinson, A.C., Buettner, F., Macaulay, I.C., Jawaid, W., Diamanti, E., Nishikawa, S.I., Piterman, N., Kouskoff, V., Theis, F.J., Fisher, J. and Göttgens, B.
Nature Biotechnology 33
(3): 269-276.
March 2015
CXCR4 has a dual role in improving the efficacy of BCMA redirected CAR-NK cells in multiple myeloma.
Moles, M.W., Erdlei, H., Menzel, L., Massaro, M., Fiori, A., Bunse, M., Schrimpf, M., Gerlach, K., Gudipati, V., Reiser, J., Mathavan, K., Goodrich, J., Huppa, J.B., Kroenke, J., Valamehr, B., Höpken, U.E. and Rehm, A.
Frontiers in Immunology 15
: 1383136.
24 June 2024
Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway.
Momeny, M., Ghasemi, R., Valenti, G., Miranda, M., Zekri, A., Zarrinrad, G., Javadikooshesh, S., Yaghmaie, M., Alimoghaddam, K., Ghavamzadeh, A. and Ghaffari, S.H.
Tumor Biology 37
(3): 3913-3923.
March 2016
Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Momeny, M., Saunus, J.M., Marturana, F., McCart Reed, A.E., Black, D., Sala, G., Iacobelli, S., Holland, J.D., Yu, D., Da Silva, L., Simpson, P.T., Khanna, K.K., Chenevix-Trench, G. and Lakhani, S.R.
Oncotarget 6
(6): 3932-3946.
19 February 2015
ABVD vs BEACOPP escalated in advanced-stage Hodgkin's lymphoma: Results from a multicenter European study.
Mondello, P., Musolino, C., Dogliotti, I., Bohn, J.P., Cavallo, F., Ferrero, S., Botto, B., Cerchione, C., Nappi, D., De Lorenzo, S., Martinelli, G., Wolf, D., Schmitt, C., Loseto, G., Cuzzocrea, S., Willenbacher, W., Mian, M. and Straus, D.J.
American Journal of Hematology 95
(9): 1030-1037.
September 2020
AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication.
Monjé, N., Dragomir, M.P., Sinn, B.V., Hoffmann, I., Makhmut, A., Simon, T., Kunze, C.A., Ihlow, J., Schmitt, W.D., Pohl, J., Piwonski, I., Marchenko, S., Keunecke, C., Calina, T.G., Tiso, F., Kulbe, H., Kreuzinger, C., Cacsire Castillo-Tong, D., Sehouli, J., Braicu, E.I., Denkert, C., Darb-Esfahani, S., Kübler, K., Capper, D., Coscia, F., Morkel, M., Horst, D., Sers, C. and Taube, E.T.
British Journal of Cancer 13
(8): 1249-1260.
3 May 2024
Evaluation of polygenic scoring methods in five biobanks shows larger variation between biobanks than methods and finds benefits of ensemble learning.
Monti, R., Eick, L., Hudjashov, G., Läll, K., Kanoni, S., Wolford, B.N., Wingfield, B., Pain, O., Wharrie, S., Jermy, B., McMahon, A., Hartonen, T., Heyne, H., Mars, N., Lambert, S., Hveem, K., Inouye, M., van Heel, D.A., Mägi, R., Marttinen, P., Ripatti, S., Ganna, A. and Lippert, C.
American Journal of Human Genetics 111
(7): 1431-1447.
11 July 2024
Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.
Monti, R., Rautenstrauch, P., Ghanbari, M., James, A.R., Kirchler, M., Ohler, U., Konigorski, S. and Lippert, C.
Nature Communications 13
(1): 5332.
10 September 2022
EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization.
Moren, B., Shah, C., Howes, M.T., Schieber, N.L., McMahon, H.T., Parton, R.G., Daumke, O. and Lundmark, R.
Molecular Biology of the Cell 23
(7): 1316-1329.
9 February 2012
Variability of an early developmental cell population underlies stochastic laterality defects.
Moreno-Ayala, R., Olivares-Chauvet, P., Schäfer, R. and Junker, J.P.
Cell Reports 34
(2): 108606.
12 January 2021
Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca, P., Jäntti, N.Z., Godbole, R., Sommer, C., Jacquemet, G., Al-Akhrass, H., Conway, J.R.W., Kronqvist, P., Kallionpää, R.E., Oliveira-Ferrer, L., Cervero, P., Linder, S., Aepfelbacher, M., Zauber, H., Rae, J., Parton, R.G., Disanza, A., Scita, G., Mayor, S., Selbach, M., Veltel, S. and Ivaska, J.
Nature Cell Biology 23
(10): 1073-1084.
October 2021
Transcriptional control of tissue formation throughout root development.
Moreno-Risueno, M.A., Sozzani, R., Yardımcı, G.G., Petricka, J.J., Vernoux, T., Blilou, I., Alonso, J., Winter, C.M., Ohler, U., Scheres, B. and Benfey, P.N.
Science 350
(6259): 426-430.
23 October 2015
Helicobacter pylori depletes cholesterol in gastric glands to prevent interferon gamma signaling and escape the inflammatory response.
Morey, P., Pfannkuch, L., Pang, E., Boccellato, F., Sigal, M., Imai-Matsushima, A., Dyer, V., Koch, M., Mollenkopf, H.J., Schlaermann, P. and Meyer, T.F.
Gastroenterology 154
(5): 1391-1404.
April 2018
Sequence specificity of single-stranded DNA-binding proteins: a novel DNA microarray approach.
Morgan, H.P., Estibeiro, P., Wear, M.A., Max, K.E., Heinemann, U., Cubeddu, L., Gallagher, M.P., Sadler, P.J. and Walkinshaw, M.D.
Nucleic Acids Research 35
(10): e75.
May 2007
Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning.
Morgani, S.M., Metzger, J.J., Nichols, J., Siggia, E.D. and Hadjantonakis, A.K.
eLife 7
: e32839.
7 February 2018
Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.
Morgenstern, Y., Das Adhikari, U., Ayyash, M., Elyada, E., Tóth, B., Moor, A., Itzkovitz, S. and Ben-Neriah, Y.
EMBO Journal 36
(20): 3046-3061.
16 October 2017
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.
Morin, R.D., Mendez-Lago, M., Mungall, A.J., Goya, R., Mungall, K.L., Corbett, R.D., Johnson, N.A., Severson, T.M., Chiu, R., Field, M., Jackman, S., Krzywinski, M., Scott, D.W., Trinh, D.L., Tamura-Wells, J., Li, S., Firme, M.R., Rogic, S., Griffith, M., Chan, S., Yakovenko, O., Meyer, I.M., Zhao, E.Y., Smailus, D., Moksa, M., Chittaranjan, S., Rimsza, L., Brooks-Wilson, A., Spinelli, J.J., Ben-Neriah, S., Meissner, B., Woolcock, B., Boyle, M., McDonald, H., Tam, A., Zhao, Y., Delaney, A., Zeng, T., Tse, K., Butterfield, Y., Birol, I., Holt, R., Schein, J., Horsman, D.E., Moore, R., Jones, S.J.M., Connors, J.M., Hirst, M., Gascoyne, R.D. and Marra, M.A.
Nature 476
(7360): 298-303.
18 August 2011
β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.
Morkel, M., Huelsken, J., Wakamiya, M., Ding, J., van de Wetering, M., Clevers, H., Taketo, M.M., Behringer, R.R., Shen, M.M. and Birchmeier, W.
Development 130
(25): 6283-6294.
1 January 2003
A phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory mantle cell lymphoma.
Morschhauser, F., Seymour, J.F., Kluin-Nelemans, H.C., Grigg, A., Wolf, M., Pfreundschuh, M., Tilly, H., Raemaekers, J., van't Veer, M.B., Milpied, N., Cartron, G., Pezzutto, A., Spencer, A., Reyes, F. and Dreyling, M.
Annals of Oncology 19
(2): 247-253.
February 2008
Paired-end analysis of transcription start sites in Arabidopsis reveals plant-specific promoter signatures.
Morton, T., Petricka, J., Corcoran, D.L., Li, S., Winter, C.M., Carda, A., Benfey, P.N., Ohler, U. and Megraw, M.
Plant Cell 26
(7): 2746-2760.
July 2014
Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis.
Moshkovits, I., Kaminitz, A., Reuveni, D., Pasmanik-Chor, M., Brazowski, E., Mildner, A., Leutz, A. and Zigmond, E.
Immunity, inflammation and disease 10
(11): e728.
November 2022
M-CSF instructs myeloid lineage fate in single haematopoietic stem cells.
Mossadegh-Keller, N., Sarrazin, S., Kandalla, P.K., Espinosa, L., Stanley, E.R., Nutt, S.L., Moore, J. and Sieweke, M.H.
Nature 497
(7448): 239-243.
9 May 2013
Developmental origin and maintenance of distinct testicular macrophage populations.
Mossadegh-Keller, N., Gentek, R., Gimenez, G., Bigot, S., Mailfert, S. and Sieweke, M.H.
Journal of Experimental Medicine 214
(10): 2829-2841.
2 October 2017
Characterization of mouse adult testicular macrophage populations by immunofluorescence imaging and flow cytometry.
Mossadegh-Keller, N. and Sieweke, M.H.
Bio-protocol 9
(5): e3178.
5 March 2019
Testicular macrophages: guardians of fertility.
Mossadegh-Keller, Noushin and Sieweke, M.H.
Cellular Immunology 330
: 120-125.
August 2018
From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement.
Mostinski, Y., Heynen, G.J.J.E., López-Alberca, M.P., Paul, J., Miksche, S., Radetzki, S., Schaller, D., Shanina, E., Seyffarth, C., Kolomeets, Y., Ziebart, N., de Schryver, J., Oestreich, S., Neuenschwander, M., Roske, Y., Heinemann, U., Rademacher, C., Volkamer, A., von Kries, J.P., Birchmeier, W. and Nazaré, M.
Journal of Medicinal Chemistry 63
(23): 14780-14804.
10 December 2020
A quantitative modular modeling approach reveals the effects of different A20 feedback implementations for the NF-κB signaling dynamics.
Mothes, J., Ipenberg, I., Arslan, S.Ç., Benary, U., Scheidereit, C. and Wolf, J.
Frontiers in Physiology 11
: 896.
28 July 2020
Successful generation of fully human, second generation, anti-CD19 CAR T cells for clinical use in patients with diverse autoimmune disorders.
Mougiakakos, D., Sengupta, R., Gold, R., Schroers, R., Haghikia, A., Lorente, M., Pendleton, M., Register, A., Heesen, C., Kröger, N., Schett, G., Mackensen, A., Podoll, A., Gutman, J., Furie, R., Bayer, R., Distler, J.H.W., Dietrich, S., Krönke, G., Bullinger, L. and Walker, K.
Cytotherapy
5 October 2024
(In Press)
Synthesis and biological evaluation of spin-labeled alkylphospholipid analogs.
Mravljak, J., Zeisig, R. and Pecar, S.
Journal of Medicinal Chemistry 48
(20): 6393-6399.
6 October 2005
Assessment of coronary artery disease during hospitalization for cancer treatment.
Mrotzek, S.M., Lena, A., Hadzibegovic, S., Ludwig, R., Al-Rashid, F., Mahabadi, A.A., Mincu, R.I., Michel, L., Johannsen, L., Hinrichs, L., Schuler, M., Keller, U., Anker, S.D., Landmesser, U., Rassaf, T., Anker, M.S. and Totzeck, M.
Clinical Research in Cardiology 110
(2): 200-210.
February 2021
Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability.
Mrozek, A., Petrowsky, H., Sturm, I., Kraus, J., Hermann, S., Hauptmann, S., Lorenz, M., Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 10
(4): 461-467.
1 April 2003
β-catenin is required for specification of proximal/distal cell fate during lung morphogenesis.
Mucenski, M.L., Wert, S.E., Nation, J.M., Loudy, D.E., Huelsken, J., Birchmeier, W., Morrisey, E.E. and Whitsett, J.A.
Journal of Biological Chemistry 278
(41): 40231-40238.
10 October 2003
CLK2 and CLK4 are regulators of DNA damage-induced NF-κB targeted by novel small molecule inhibitors.
Mucka, P., Lindemann, P., Bosco, B., Willenbrock, M., Radetzki, S., Neuenschwander, M., Brischetto, C., von Kries, J.P., Nazaré, M. and Scheidereit, C.
Cell Chemical Biology 30
(10): 1303-1312.e3.
19 October 2023
Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression.
Mudduluru, G., Ilm, K., Fuchs, S. and Stein, U.
Oncotarget 8
(13): 21081-21094.
28 March 2017
Transduction efficiency of MLV but not of HIV-1 vectors is pseudotype dependent on human primary T lymphocytes.
Muehlebach, M.D., Schmitt, I., Steidl, S., Stitz, J., Schweizer, M., Blankenstein, T., Cichutek, K. and Uckert, W.
Journal of Molecular Medicine 81
(12): 801-810.
December 2003
New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108).
Mueller, A., Mueller, J.J., Muller, Y.A., Uhlmann, H., Bernhardt, R. and Heinemann, U.
Structure 6
(3): 269-280.
15 March 1998
Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma.
Mueller, A., Zang, C., Chumduri, C., Doerken, B., Daniel, P.T. and Scholz, C.W.
International Journal of Cancer 133
(8): 1813-1824.
15 October 2013
The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest.
Mueller, C., Calkhoven, C.F., Sha, X.J. and Leutz, A.
Journal of Biological Chemistry 279
(8): 7353-7358.
1 January 2004
Shaping up adaptive immunity: The impact of CCR7 and CXCR5 on lymphocyte trafficking.
Mueller, G. and Lipp, M.
Microcirculation 10
(3-4): 325-334.
July 2003
An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri phage Sf6.
Mueller, J.J., Barbirz, S., Heinle, K., Freiberg, A., Seckler, R. and Heinemann, U.
Structure 16
(5): 766-775.
7 May 2008
Glass-capillary collimator for distance compensation and partial monochromatization at rotating-anode X-ray generators.
Mueller, J.J., Gorny, H.E., Schmalz, J. and Heinemann, U.
Journal of Applied Crystallography 28
(Pt 6): 853-855.
1 December 1995
Structural and thermodynamic characterization of the adrenodoxin-like domain of the electron-transfer protein Etp1 from Schizosaccharomyces pombe.
Mueller, J.J., Hannemann, F., Schiffler, B., Ewen, K.M., Kappl, R., Heinemann, U. and Bernhardt, R.
Journal of Inorganic Biochemistry 105
(7): 957-965.
July 2011
A study of high-resolution x-ray scattering data evaluation by the maximum-entropy method.
Mueller, J.J. and Hansen, S.
Journal of Applied Crystallography 27
(Pt 3): 257-270.
1 June 1994
Multimodal particle size distribution or fractal surface of acrylic acid copolymer nanoparticles: A small-angle X-ray scattering study using direct Fourier and indirect maximum entropy methods.
Mueller, J.J., Hansen, S., Lukowski, G. and Gast, K.
Journal of Applied Crystallography 28
(Pt 6): 774-781.
1 December 1995
The use of small-angle scattering and the maximum-entropy method for shape-model determination from distance-distribution functions.
Mueller, J.J., Hansen, S. and Puerschel, H.V.
Journal of Applied Crystallography 29
(Pt 5): 547-554.
1 October 1996
Modeling of electrostatic recognition processes in the mammalian mitochondrial steroid hydroxylase system.
Mueller, J.J., Lapko, A., Ruckpaul, K. and Heinemann, U.
Biophysical Chemistry 100
(1-3): 281-292.
December 2002
Low-resolution ab initio phasing of Sarcocystis muris lectin SML-2.
Mueller, J.J., Lunina, N.L., Urzhumtsev, A., Weckert, E., Heinemann, U. and Lunin, V.Y.
Acta Crystallographica Section D 62
(Pt 5): 533-540.
May 2006
AKIMA interpolation: A tool used in direct slit-length desmearing procedures of non-frequency- limited X-ray scattering curves.
Mueller, J.J., Mueller, E.C., Gernat, C. and Kroeber, R.
Journal of Applied Crystallography 28
(Pt 1): 38-42.
1 February 1995
Crystal structure of barley 1,3-1,4-beta-glucanase at 2.0-A resolution and comparison with Bacillus 1,3-1,4-beta-glucanase.
Mueller, J.J., Thomsen, K.K. and Heinemann, U.
Journal of Biological Chemistry 273
(6): 3438-3446.
6 February 1998
PAN-modular structure of microneme protein SML-2 from the parasite Sarcocystis muris at 1.95 Å resolution and its complex with 1-thio-β-D-galactose.
Mueller, J.J., Weiss, M.S. and Heinemann, U.
Acta Crystallographica Section D 67
(Pt 11): 936-944.
November 2011
Protective capacity of virus-specific T cell receptor (TCR)-transduced CD8 T cells in vivo.
Mueller, K., von Maessenhausen, A., Aichele, U., Staerck, L., Leisegang, M., Uckert, W. and Pircher, H.
Journal of Virology 86
(19): 10866-10869.
October 2012
ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Mueller, T., Stein, U., Poletti, A., Garzia, L., Rothley, M., Plaumann, D., Thiele, W., Bauer, M., Galasso, A., Schlag, P., Pankratz, M., Zollo, M. and Sleeman, J.P.
Oncogene 29
(16): 2393-2403.
22 April 2010
The macromolecular crystallography beamlines at BESSY II of the Helmholtz-Zentrum Berlin: current status and perspectives.
Mueller, U., Foerster, R., Hellmig, M., Huschmann, F.U., Kastner, A., Malecki, P., Puehringer, S., Roewer, M., Sparta, K., Steffien, M., Uehlein, M., Wilk, P. and Weiss, M.S.
European Physical Journal Plus 130
(7): 141.
July 2015
Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags.
Mueller, U., Buessow, K., Diehl, A., Bartl, F.J., Niesen, F.H., Nyarsik, L. and Heinemann, U.
Journal of Structural and Functional Genomics 4
(4): 217-225.
December 2003
Natural proteome diversity links aneuploidy tolerance to protein turnover.
Muenzner, J., Trébulle, P., Agostini, F., Zauber, H., Messner, C.B., Steger, M., Kilian, C., Lau, K., Barthel, N., Lehmann, A., Textoris-Taube, K., Caudal, E., Egger, A.S., Amari, F., De Chiara, M., Demichev, V., Gossmann, T.I., Mülleder, M., Liti, G., Schacherer, J., Selbach, M., Berman, J. and Ralser, M.
Nature 630
(8015): 149-157.
6 June 2024
p14ARF-induced apoptosis in p53-deficient cells is mediated by the BH3-only protein independent de-repression of Bak through down-regulation of Mcl-1 and Bcl-xL.
Muer, A., Overkamp, T., Gillissen, B., Richter, A., Pretzsch, T., Milojkovic, A., Doerken, B., Daniel, P.T. and Hemmati, P.
Journal of Biological Chemistry 287
(21): 17343-17352.
18 May 2012
Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A., Sengul, T.G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M.H., Ofenbauer, A., Gesell-Salazar, M., Balogh, A., Kempa, S., Tursun, B., Robbins, C.T., Völker, U., Chen, W., Nelson, L. and Gotthardt, M.
Scientific Reports 9
(1): 19976.
27 December 2019
MatK impacts differential chloroplast translation by limiting spliced tRNA-K(UUU) abundance.
Muino, J.M., Ruwe, H., Qu, Y., Maschmann, S., Chen, W., Zoschke, R., Ohler, U., Kaufmann, K. and Schmitz-Linneweber, C.
Plant Journal 119
(6): 2737-2752.
September 2024
Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.
Mukherjee, N., Corcoran, D.L., Nusbaum, J.D., Reid, D.W., Georgiev, S., Hafner, M., Ascano, M., Tuschl, T., Ohler, U. and Keene, J.D.
Molecular Cell 43
(3): 327-339.
5 August 2011
Global target mRNA specification and regulation by the RNA-binding protein ZFP36.
Mukherjee, N., Jacobs, N.C., Hafner, M., Kennington, E.A., Nusbaum, J.D., Tuschl, T., Blackshear, P.J. and Ohler, U.
Genome Biology 15
(1): R12.
8 January 2014
Integrative classification of human coding and noncoding genes through RNA metabolism profiles.
Mukherjee, N., Calviello, L., Hirsekorn, A., de Pretis, S., Pelizzola, M. and Ohler, U.
Nature Structural & Molecular Biology 24
(1): 86-96.
January 2017
Deciphering human ribonucleoprotein regulatory networks.
Mukherjee, N., Wessels, H.H., Lebedeva, S., Sajek, M., Ghanbari, M., Garzia, A., Munteanu, A., Yusuf, D., Farazi, T., Hoell, J.I., Akat, K.M., Akalin, A., Tuschl, T. and Ohler, U.
Nucleic Acids Research 47
(2): 570-581.
25 January 2019
Diverse epigenetic strategies interact to control epidermal differentiation.
Mulder, K.W., Wang, X., Escriu, C., Ito, Y., Schwarz, R.F., Gillis, J., Sirokmany, G., Donati, G., Uribe-Lewis, S., Pavlidis, P., Murrell, A., Markowetz, F. and Watt, F.M.
Nature Cell Biology 14
(7): 753-763.
24 June 2012
Deep Visual Proteomics defines single-cell identity and heterogeneity.
Mund, A., Coscia, F., Kriston, A., Hollandi, R., Kovács, F., Brunner, A.D., Migh, E., Schweizer, L., Santos, A., Bzorek, M., Naimy, S., Rahbek-Gjerdrum, L.M., Dyring-Andersen, B., Bulkescher, J., Lukas, C., Eckert, M.A., Lengyel, E., Gnann, C., Lundberg, E., Horvath, P. and Mann, M.
Nature Biotechnology 40
(8): 1231-1240.
August 2022
Lymphoma outbreak in a GASH: Sal hamster colony.
Munoz, L.J., Ludena, D., Gedvilaite, A., Zvirbliene, A., Jandrig, B., Voronkova, T., Ulrich, R.G. and Lopez, D.E.
Archives of Virology 158
(11): 2255-2265.
November 2013
The influence of Mn2+ on DNA structure in the presence of Na+ ions: a Raman spectroscopic study.
Muntean, C.M., Misselwitz, R. and Welfle, H.
Spectroscopy 20
(5-6): 261-268.
2006
SSMART: Sequence-structure motif identification for RNA-binding proteins.
Munteanu, A., Mukherjee, N. and Ohler, U.
Bioinformatics 34
(23): 3990-3998.
1 December 2018
COUGER-co-factors associated with uniquely-bound genomic regions.
Munteanu, A., Ohler, U. and Gordân, R.
Nucleic Acids Research 42
(Web Server issue): W461-W467.
July 2014
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.
Murakawa, Y., Hinz, M., Mothes, J., Schuetz, A., Uhl, M., Wyler, E., Yasuda, T., Mastrobuoni, G., Friedel, C.C., Dölken, L., Kempa, S., Schmidt-Supprian, M., Blüthgen, N., Backofen, R., Heinemann, U., Wolf, J., Scheidereit, C. and Landthaler, M.
Nature Communications 6
: 7367.
14 July 2015
The pseudogenes of Mycobacterium leprae reveal the functional relevance of gene order within operons.
Muro, E.M., Mah, N., Moreno-Hagelsieb, G. and Andrade-Navarro, M.A.
Nucleic Acids Research 39
(5): 1732-1738.
1 March 2011
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Muus, C., Luecken, M.D., Eraslan, G., Sikkema, L., Waghray, A., Heimberg, G., Kobayashi, Y., Vaishnav, E.D., Subramanian, A., Smillie, C., Jagadeesh, K.A., Duong, E.T., Fiskin, E., Triglia, E.T., Ansari, M., Cai, P., Lin, B., Buchanan, J., Chen, S., Shu, J., Haber, A.L., Chung, H., Montoro, D.T., Adams, T., Aliee, H., Allon, S.J., Andrusivova, Z., Angelidis, I., Ashenberg, O., Bassler, K., Bécavin, C., Benhar, I., Bergenstråhle, J., Bergenstråhle, L., Bolt, L., Braun, E., Bui, L.T., Callori, S., Chaffin, M., Chichelnitskiy, E., Chiou, J., Conlon, T.M., Cuoco, M.S., Cuomo, A.S.E., Deprez, M., Duclos, G., Fine, D., Fischer, D.S., Ghazanfar, S., Gillich, A., Giotti, B., Gould, J., Guo, M., Gutierrez, A.J., Habermann, A.C., Harvey, T., He, P., Hou, X., Hu, L., Hu, Y., Jaiswal, A., Ji, L., Jiang, P., Kapellos, T.S., Kuo, C.S., Larsson, L., Leney-Greene, M.A., Lim, K., Litviňuková, M., Ludwig, L.S., Lukassen, S., Luo, W., Maatz, H., Madissoon, E., Mamanova, L., Manakongtreecheep, K., Leroy, S., Mayr, C.H., Mbano, I.M., McAdams, A.M., Nabhan, A.N., Nyquist, S.K., Penland, L., Poirion, O.B., Poli, S., Qi, C.C., Queen, R., Reichart, D., Rosas, I., Schupp, J.C., Shea, C.V., Shi, X., Sinha, R., Sit, R.V., Slowikowski, K., Slyper, M., Smith, N.P., Sountoulidis, A., Strunz, M., Sullivan, T.B., Sun, D., Talavera-López, C., Tan, P., Tantivit, J., Travaglini, K.J., Tucker, N.R., Vernon, K.A., Wadsworth, M.H., Waldman, J., Wang, X., Xu, K., Yan, W., Zhao, W. and Ziegler, C.G.K.
Nature Medicine 27
(3): 546-559.
2 March 2021
Single-cell analysis based dissection of clonality in myelofibrosis.
Mylonas, E., Yoshida, K., Frick, M., Hoyer, K., Christen, F., Kaeda, J., Obenaus, M., Noerenberg, D., Hennch, C., Chan, W., Ochi, Y., Shiraishi, Y., Shiozawa, Y., Zenz, T., Oakes, C.C., Sawitzki, B., Schwarz, M., Bullinger, L., le Coutre, P., Rose-Zerilli, M.J.J., Ogawa, S. and Damm, F.
Nature Communications 11
(1): 73.
7 January 2020
Mice with renal-specific alterations 1 of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors.
Myszczyszyn, A., Popp, O., Kunz, S., Sporbert, A., Jung, S., Penning, L.C., Fendler, A., Mertins, P. and Birchmeier, W.
PLoS ONE 19
(3): e0282938.
21 March 2024
Adjustments to the reference dataset design improve cell type label transfer.
Mölbert, C. and Haghverdi, L.
Frontiers in Bioinformatics 3
: 1150099.
5 April 2023
Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Mönke, G., Cristiano, E., Finzel, A., Friedrich, D., Herzel, H., Falcke, M. and Loewer, A.
Scientific Reports 7
: 46571.
18 April 2017
Gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice.
Mühlgrabner, V., Plach, A., Holler, J., Leitner, J., Steinberger, P., Dupré, L., Göhring, J. and Huppa, J.B.
Methods in Cell Biology
15 April 2024
(In Press)
Pan-class I PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.
Müller, A., Gillissen, B., Richter, A., Richter, A., Chumduri, C., Daniel, P.T. and Scholz, C.W.
Cell Death & Disease 9
(3): 384.
7 March 2018
Systemic immunoregulatory and pathogenic functions of homeostatic chemokine receptors.
Müller, G., Höpken, U.E., Stein, H. and Lipp, M.
Journal of Leukocyte Biology 72
(1): 1-8.
July 2002
Role of homeostatic chemokine and sphingosine-1-phosphate receptors in the organization of lymphoid tissue.
Müller, G., Reiterer, P., Höpken, U.E., Golfier, S. and Lipp, M.
Annals of the New York Academy of Sciences 987
: 107-116.
April 2003
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Müller, P.M., Rademacher, J., Bagshaw, R.D., Wortmann, C., Barth, C., van Unen, J., Alp, K.M., Giudice, G., Eccles, R.L., Heinrich, L.E., Pascual-Vargas, P., Sanchez-Castro, M., Brandenburg, L., Mbamalu, G., Tucholska, M., Spatt, L., Czajkowski, M.T., Welke, R.W., Zhang, S., Nguyen, V., Rrustemi, T., Trnka, P., Freitag, K., Larsen, B., Popp, O., Mertins, P., Gingras, A.C., Roth, F.P., Colwill, K., Bakal, C., Pertz, O., Pawson, T., Petsalaki, E. and Rocks, O.
Nature Cell Biology 22
(4): 498-511.
April 2020
Plasmodium sporozoite motility is modulated by the turnover of discrete adhesion sites.
Münter, S., Sabass, B., Selhuber-Unkel, C., Kudryashev, M., Hegge, S., Engel, U., Spatz, J.P., Matuschewski, K., Schwarz, U.S. and Frischknecht, F.
Cell Host & Microbe 6
(6): 551-562.
17 December 2009
The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S., Uyar, B., He, M., Krause, A., Vitrinel, B., Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S., Akalin, A. and Tursun, B.
Aging Cell 18
(6): e13012.
December 2019
Identification of truncated chemokine receptor 7 in human colorectal cancer unable to localize to the cell surface and unreactive to external ligands.
Na, I.K., Busse, A., Scheibenbogen, C., Ghadjar, P., Coupland, S.E., Letsch, A., Loddenkemper, C., Stroux, A., Bauer, S., Thiel, E. and Keilholz, U.
International Journal of Cancer 123
(7): 1565-1572.
1 October 2008
Addition of GM-CSF to a peptide/KLH vaccine results in increased frequencies of CXCR3-expressing KLH-specific T cells.
Na, I.K., Keilholz, U., Letsch, A., Bauer, S., Asemissen, A.M., Nagorsen, D., Thiel, E. and Scheibenbogen, C.
Cancer Immunology Immunotherapy 56
(3): 391-396.
March 2007
Quantitative RT-PCR of Wilms tumor gene transcripts (WT1) for the molecular monitoring of patients with accelerated phase bcr/abl + CML.
Na, I.K., Kreuzer, K.A., Lupberger, J., Doerken, B. and Coutre, P.
Leukemia Research Reports 29
(3): 343-345.
1 March 2005
Emerging role of tyrosine kinases as drugable targets in cancer.
Na, I.K. and Le Coutre, P.
Biomarker Insights 10
(S3): 29-31.
10 September 2015
Human bone marrow as a source to generate CMV-specific CD4+ T cells with multifunctional capacity.
Na, I.K., Letsch, A., Guerreiro, M., Bauer, S., Noack, I., Geginat, J., Reinke, P., Loesch, M., Kienapfel, H., Thiel, E., Volk, H.D. and Scheibenbogen, C.
Journal of Immunotherapy 32
(9): 907-913.
November 2009
The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.
Na, I.K., Lu, S.X., Yim, N.L., Goldberg, G.L., Tsai, J., Rao, U., Smith, O.M., King, C.G., Suh, D., Hirschhorn-Cymerman, D., Palomba, L., Penack, O., Holland, A.M., Jenq, R.R., Ghosh, A., Tran, H., Merghoub, T., Liu, C., Sempowski, G.D., Ventevogel, M., Beauchemin, N. and van den Brink, M.R.M.
Journal of Clinical Investigation 120
(1): 343-356.
January 2010
Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo.
Na, I.K., Markley, J.C., Tsai, J.J., Yim, N.L., Beattie, B.J., Klose, A.D., Holland, A.M., Ghosh, A., Rao, U.K., Stephan, M.T., Serganova, I., Santos, E.B., Brentjens, R.J., Blasberg, R.G., Sadelain, M. and van den Brink, M.R.M.
Blood 116
(11): e18-e25.
16 September 2010
Nuclear expression of CXCR4 in tumor cells of non-small cell lung cancer is correlated with lymph node metastasis.
Na, I.K., Scheibenbogen, C., Adam, C., Stroux, A., Ghadjar, P., Thiel, E., Keilholz, U. and Coupland, S.E.
Human Pathology 39
(12): 1751-1755.
December 2008
Rabbit antithymocyte globulin (Thymoglobulin(R)) impairs the thymic output of both conventional and regulatory CD4(+) T cells after allogeneic hematopoietic stem cell transplantation in adult patients.
Na, I.K., Wittenbecher, F., Dziubianau, M., Herholz, A., Mensen, A., Kunkel, D., Blau, O., Blau, I., Thiel, E., Uharek, L., Scheibenbogen, C., Rieger, K. and Thiel, A.
Haematologica 98
(1): 23-30.
January 2013
Current clinical practice and challenges in the management of secondary immunodeficiency in hematological malignancies.
Na, I.K., Buckland, M., Agostini, C., Edgar, J.D.M., Friman, V., Michallet, M., Sánchez-Ramón, S., Scheibenbogen, C. and Quinti, I.
European Journal of Haematology 102
(6): 447-456.
June 2019
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Naba, A., Clauser, K.R., Hoersch, S., Liu, H., Carr, S.A. and Hynes, R.O.
Molecular & Cellular Proteomics 11
(4): M111.014647.
1 April 2012
Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation.
Naerhi, K., Jaervinen, E., Birchmeier, W., Taketo, M.M., Mikkola, M.L. and Thesleff, I.
Development 135
(6): 1019-1028.
March 2008
Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Nagel, D., Spranger, S., Vincendeau, M., Grau, M., Raffegerst, S., Kloo, B., Hlahla, D., Neuenschwander, M., von Kries, J.P., Hadian, K., Doerken, B., Lenz, P., Lenz, G., Schendel, D.J. and Krappmann, D.
Cancer Cell 22
(6): 825-837.
11 December 2012
Epidemiological, genetic, and clinical characterization by age of newly diagnosed acute myeloid leukemia based on an academic population-based registry study (AMLSG BiO).
Nagel, G., Weber, D., Fromm, E., Erhardt, S., Lübbert, M., Fiedler, W., Kindler, T., Krauter, J., Brossart, P., Kündgen, A., Salih, H.R., Westermann, J., Wulf, G., Hertenstein, B., Wattad, M., Götze, K., Kraemer, D., Heinicke, T., Girschikofsky, M., Derigs, H.G., Horst, H.A., Rudolph, C., Heuser, M., Göhring, G., Teleanu, V., Bullinger, L., Thol, F., Gaidzik, V.I., Paschka, P., Döhner, K., Ganser, A., Döhner, H. and Schlenk, R.F.
Annals of Hematology 96
(12): 1993-2003.
1 December 2017
CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.
Nakamoto, N., Ebinuma, H., Kanai, T., Chu, P.S., Ono, Y., Mikami, Y., Ojiro, K., Lipp, M., Love, P.E., Saito, H. and Hibi, T.
Gastroenterology 142
(2): 366-376.
February 2012
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
Nandakumar, S.K., McFarland, S.K., Mateyka, L.M., Lareau, C.A., Ulirsch, J.C., Ludwig, L.S., Agarwal, G., Engreitz, J.M., Przychodzen, B., McConkey, M., Cowley, G.S., Doench, J.G., Maciejewski, J.P., Ebert, B.L., Root, D.E. and Sankaran, V.G.
eLife 8
: e44080.
9 May 2019
Structure of a bacterial type III secretion system in contact with a host membrane in situ.
Nans, A., Kudryashev, M., Saibil, H.R. and Hayward, R.D.
Nature Communications 6
: 10114.
11 December 2015
Informative priors based on transcription factor structural class improve de novo motif discovery.
Narlikar, L., Gordan, R., Ohler, U. and Hartemink, A.J.
Bioinformatics 22
(14): e384-392.
15 July 2006
Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response.
Nasri, M., Mir, P., Dannenmann, B., Amend, D., Skroblyn, T., Xu, Y., Schulze-Osthoff, K., Klimiankou, M., Welte, K. and Skokowa, J.
Blood Advances 3
(1): 63-71.
8 January 2019
Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR.
Nassenstein, C., Kammertoens, T., Veres, T.Z., Uckert, W., Spies, E., Fuchs, B., Krug, N. and Braun, A.
Journal of Allergy and Clinical Immunology 120
(5): 1089-1096.
November 2007
Identification of the elementary structural units of the DNA damage response.
Natale, F., Rapp, A., Yu, W., Maiser, A., Harz, H., Scholl, A., Grulich, S., Anton, T., Hoerl, D., Chen, W., Durante, M., Taucher-Scholz, G., Leonhardt, H. and Cardoso, M.C.
Nature Communications 8
: 15760.
12 June 2017
Predicting cell-type-specific gene expression from regions of open chromatin.
Natarajan, A., Yardimci, G.G., Sheffield, N.C., Crawford, G.E. and Ohler, U.
Genome Research 22
(9): 1711-1722.
September 2012
TCR-ligand k(off) rate correlates with the protective capacity of antigen-specific CD8(+) T cells for adoptive transfer.
Nauerth, M., Weissbrich, B., Knall, R., Franz, T., Dössinger, G., Bet, J., Paszkiewicz, P.J., Pfeifer, L., Bunse, M., Uckert, W., Holtappels, R., Gillert-Marien, D., Neuenhahn, M., Krackhardt, A., Reddehase, M.J., Riddell, S.R. and Busch, D.H.
Science Translational Medicine 5
(192): 192ra87.
3 July 2013
The NF-kappaB precursor p105 and the proto-oncogene product Bcl- 3 are I kappa B molecules and control nuclear translocation of NF-kappa B.
Naumann, M., Wulczyn, F.G. and Scheidereit, C.
EMBO Journal 12
(1): 213-222.
January 1993
Adenoviral natural born killer gene therapy for malignant glioma.
Naumann, U., Schmidt, F., Wick, W., Frank, B., Weit, S., Gillissen, B., Daniel, P. and Weller, M.
Human Gene Therapy 14
(13): 1235-1246.
1 September 2003
Linoleic acid potentiates CD8(+) T cell metabolic fitness and antitumor immunity.
Nava Lauson, C.B., Tiberti, S., Corsetto, P.A., Conte, F., Tyagi, P., Machwirth, M., Ebert, S., Loffreda, A., Scheller, L., Sheta, D., Mokhtari, Z., Peters, T., Raman, A.T., Greco, F., Rizzo, A.M., Beilhack, A., Signore, G., Tumino, N., Vacca, P., McDonnell, L.A., Raimondi, A., Greenberg, P.D., Huppa, J.B., Cardaci, S., Caruana, I., Rodighiero, S., Nezi, L. and Manzo, T.
Cell Metabolism 35
(4): 633-650.e9.
4 April 2023
Protein kinase C inhibitor Sotrastaurin selectively inhibits the growth of CD79-mutant diffuse large B-cell lymphomas.
Naylor, T.L., Tang, H., Ratsch, B.A., Enns, A., Loo, A., Chen, L., Lenz, P., Schuler, W., Doerken, B., Yao, Y.M., Warmuth, M., Lenz, G. and Stegmeier, F.
Cancer Research 71
(7): 2643-2653.
1 April 2011
H-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signaling.
Nazarenko, I., Kristiansen, G., Fonfara, S., Guenther, R., Gieseler, C., Kemmner, W., Schaefer, R., Petersen, I. and Sers, C.
American Journal of Pathology 169
(4): 1427-1439.
October 2006
The immediate early gene Ier2 promotes tumor cell motility and metastasis, and predicts poor survival of colorectal cancer patients.
Neeb, A., Wallbaum, S., Novac, N., Dukovic-Schulze, S., Scholl, I., Schreiber, C., Schlag, P., Moll, J., Stein, U. and Sleeman, J.P.
Oncogene 31
(33): 3796-3806.
August 2012
Luminal CD4 + T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation.
Nemoto, Y., Kanai, T., Shinohara, T., Ito, T., Nakamura, T., Okamoto, R., Tsuchiya, K., Lipp, M., Eishi, Y. and Watanabe, M.
Gastroenterology 141
(6): 2130-2139.e11.
December 2011
Distinct C/EBP functions are required for eosinophil lineage commitment and maturation.
Nerlov, C., McNagny, K.M., Doederlein, G., Kowenz-Leutz, E. and Graf, T.
Genes & Development 12
(15): 2413-2423.
1 August 1998
Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types.
Ness, S.A., Kowenz-Leutz, E., Casini, T., Graf, T. and Leutz, A.
Genes & Development 7
(5): 749-759.
May 1993
Diagnostik, Therapie und Verlaufskontrolle des Diabetes mellitus im Kindes- und Jugendalter - AWMF-Registernummer 057-016 [Diagnosis, therapy and follow-up of diabetes mellitus in children and adolescents - AWMF-Registry-Number 057-016].
Neu, A., Buerger-Buesing, J., Danne, T., Dost, A., Holder, M., Holl, R.W., Holterhus, P.M., Kapellen, T., Karges, B., Kordonouri, O., Mueller, S., Raile, K., Schweizer, R., von Sengbusch, S., Stachow, R., Wagner, V., Wiegand, S. and Ziegler, R.
Diabetologie und Stoffwechsel 11
(1): 35-94.
25 February 2016
The nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast.
Neuber, A., Franke, J., Wittstruck, A., Schlenstedt, G., Sommer, T. and Stade, K.
Molecular and Cellular Biology 28
(17): 5348-5358.
September 2008
Ubx2 links the Cdc48 complex to ER-associated protein degradation.
Neuber, O., Jarosch, E., Volkwein, C., Walter, J. and Sommer, T.
Nature Cell Biology 7
(10): 993-998.
18 September 2005
Successful salvage treatment of disseminated cutaneous fusariosis with liposomal amphotericin B and terbinafine after allogeneic stem cell transplantation.
Neuburger, S., Massenkeil, G., Seibold, M., Lutz, C., TammI, I., Le Coutre, P., Graf, B., Doerken, B. and Arnold, R.
Transplant Infectious Disease 10
(4): 290-293.
August 2008
BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features.
Neuendorff, N.R., Burmeister, T., Doerken, B. and Westermann, J.
Annals of Hematology 95
(8): 1211-1221.
August 2016
BCR-ABL1 acute myeloid leukemia: clonal selection of a BCR-ABL1(-) subclone as a cause of refractory disease with nilotinib treatment.
Neuendorff, N.R., Schwarz, M., Hemmati, P., Tuerkmen, S., Bommer, C., Burmeister, T., Doerken, B., le Coutre, P., Arnold, R. and Westermann, J.
Acta Haematologica 133
(2): 237-241.
2015
A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A., Bakina, O., Badillo Lisakowski, V., Olivares-Chauvet, P., Conrad, T., Gotthardt, M., Kettenmann, H. and Junker, J.P.
Molecular Systems Biology 19
(2): e11147.
10 February 2023
Preliminary evaluation of the CellFinder literature curation pipeline for gene expression in kidney cells and anatomical parts.
Neves, M., Damaschun, A., Mah, N., Lekschas, F., Seltmann, S., Stachelscheid, H., Fontaine, J.F., Kurtz, A. and Leser, U.
Database 2013
(2013): bat020.
18 April 2013
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
Ng, K.W., Boumelha, J., Enfield, K.S.S., Almagro, J., Cha, H., Pich, O., Karasaki, T., Moore, D.A., Salgado, R., Sivakumar, M., Young, G., Molina-Arcas, M., de Carné Trécesson, S., Anastasiou, P., Fendler, A., Au, L., Shepherd, S.T.C., Martínez-Ruiz, C., Puttick, C., Black, J.R.M., Watkins, T.B.K., Kim, H., Shim, S., Faulkner, N., Attig, J., Veeriah, S., Magno, N., Ward, S., Frankell, A.M., Al Bakir, M., Lim, E.L., Hill, M.S., Wilson, G.A., Cook, D.E., Birkbak, N.J., Behrens, A., Yousaf, N., Popat, S., Hackshaw, A., Hiley, C.T., Litchfield, K., McGranahan, N., Jamal-Hanjani, M., Larkin, J., Lee, S.H., Turajlic, S., Swanton, C., Downward, J. and Kassiotis, G.
Nature 616
(7957): 563-573.
20 April 2023
Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D., Ramberger, E., Bohl, S.R., Dolnik, A., Steinebach, C., Conrad, T., Müller, S., Popp, O., Kull, M., Haji, M., Gütschow, M., Döhner, H., Walther, W., Keller, U., Bullinger, L., Mertins, P. and Krönke, J.
Nature Communications 13
(1): 1009.
23 February 2022
Arginine methylation of the p30 C/EBPα oncoprotein regulates progenitor proliferation and myeloid differentiation.
Nguyen, L.T., Zimmermann, K., Kowenz-Leutz, E., Dörr, D., Schütz, A., Schönheit, J., Mildner, A. and Leutz, A.
iScience 27
(11): 111199.
15 November 2024
C/EBPβ-induced lymphoid-to-myeloid transdifferentiation emulates granulocyte-monocyte progenitor biology.
Nguyen, L.T., Zimmermann, K., Kowenz-Leutz, E., Lim, R., Hofstätter, M., Mildner, A. and Leutz, A.
Stem Cell Reports 19
(1): 112-125.
28 December 2023
CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model.
Nguyen-Hoai, T., Baldenhofer, G., Ahmed, M.S., Pham-Duc, M., Gries, M., Lipp, M., Doerken, B., Pezzutto, A. and Westermann, J.
Journal of Gene Medicine 14
(2): 128-137.
February 2012
CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model.
Nguyen-Hoai, T., Baldenhofer, G., Sayed Ahmed, M.S., Pham-Duc, M., Vu, M.D., Lipp, M., Doerken, B., Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 19
(1): 69-76.
January 2012
CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: improved vaccine efficacy and a role for B cells as APC.
Nguyen-Hoai, T., Hohn, O., Vu, M.D., Baldenhofer, G., Sayed Ahmed, M.S., Doerken, B., Norley, S., Lipp, M., Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 19
(12): 880-887.
December 2012
HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: gene gun is superior to jet injector in inducing CTL responses and protective immunity.
Nguyen-Hoai, T., Kobelt, D., Hohn, O., Vu, M.D., Schlag, P.M., Doerken, B., Norley, S., Lipp, M., Walther, W., Pezzutto, A. and Westermann, J.
OncoImmunology 1
(9): 1537-1545.
1 December 2012
Gene gun Her2/neu DNA vaccination: evaluation of vaccine efficacy in a syngeneic Her2/neu mouse tumor model.
Nguyen-Hoai, T., Pezzutto, A. and Westermann, J.
Methods in Molecular Biology 1317
: 17-37.
2015
Gene gun Her2/neu DNA vaccination: evaluation of vaccine efficacy in a syngeneic Her2/neu mouse tumor model.
Nguyen-Hoai, T., Hohn, O., Pezzutto, A. and Westermann, J.
Methods in Molecular Biology 2521
(3): 129-154.
23 June 2022
CCL4 as an adjuvant for DNA vaccination in a Her2/neu mouse tumor model.
Nguyen-Hoai, T., Pham-Duc, M., Gries, M., Dörken, B., Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 23
(6): 162-167.
June 2016
A paired-end sequencing strategy to map the complex landscape of transcription initiation.
Ni, T., Corcoran, D.L., Rach, E.A., Song, S., Spana, E.P., Gao, Y., Ohler, U. and Zhu, J.
Nature Methods 7
(7): 521-527.
July 2010
The patients' view: impact of the extent of resection, intraoperative imaging, and awake surgery on health-related quality of life in high-grade glioma patients-results of a multicenter cross-sectional study.
Nickel, K., Renovanz, M., König, J., Stöckelmaier, L., Hickmann, A.K., Nadji-Ohl, M., Engelke, J., Weimann, E., Freudenstein, D., Ganslandt, O., Bullinger, L., Wirtz, C.R. and Coburger, J.
Neurosurgical Review 41
(1): 207-219.
January 2018
Initial chemotherapy with mitoxantrone, chlorambucil, prednisone impairs the collection of stem cells in patients with indolent lymphomas--results of a randomized comparison by the German Low-Grade Lymphoma Study Group.
Nickenig, C., Dreyling, M., Hoster, E., Ludwig, W.D., Doerken, B., Freund, M., Huber, C., Ganser, A., Truemper, L., Forstpointner, R., Unterhalt, M. and Hiddemann, W.
Annals of Oncology 18
(1): 136-142.
January 2007
Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.
Nieborowska-Skorska, M., Sullivan, K., Dasgupta, Y., Podszywalow-Bartnicka, P., Hoser, G., Maifrede, S., Martinez, E., Di Marcantonio, D., Bolton-Gillespie, E., Cramer-Morales, K., Lee, J., Li, M., Slupianek, A., Gritsyuk, D., Cerny-Reiterer, S., Seferynska, I., Stoklosa, T., Bullinger, L., Zhao, H., Gorbunova, V., Piwocka, K., Valent, P., Civin, C.I., Muschen, M., Dick, J.E., Wang, J.C., Bhatia, S., Bhatia, R., Eppert, K., Minden, M.D., Sykes, S.M. and Skorski, T.
Journal of Clinical Investigation 127
(6): 2392-2406.
1 June 2017
An approach to quality management in structural biology: Biophysical selection of proteins for successful crystallization.
Niesen, F.H., Koch, A., Lenski, U., Harttig, U., Roske, Y., Heinemann, U. and Hofmann, K.P.
Journal of Structural Biology 162
(3): 451-459.
June 2008
Online-Diskurs zu den ethischen Fragen der Biomedizin.
Niewoehner, J. and Tannert, C.
Zeitschrift fuer Biopolitik 4
: 53-63.
1 January 2005
Participatory prognostics in Germany - developing citizen scenarios for the relationship between biomedicine and the economy in 2014.
Niewoehner, J., Wiedemann, P., Karger, C., Schicktanz, S. and Tannert, C.
Technological Forecasting and Social Change 72
(2): 195-211.
1 January 2005
Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Nikolay, R., Hilal, T., Schmidt, S., Qin, B., Schwefel, D., Vieira-Vieira, C.H., Mielke, T., Bürger, J., Loerke, J., Amikura, K., Flügel, T., Ueda, T., Selbach, M., Deuerling, E. and Spahn, C.M.T.
Molecular Cell 81
(6): 1200-1215.
18 March 2021
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret, C., Miah, S.M.S., Rota, G., Fonta, N.P., Wang, H., Held, W., Birchmeier, W., Sexl, V., Yang, W., Vivier, E., Ho, P.C., Brossay, L. and Guarda, G.
Nature Communications 10
(1): 1444.
29 March 2019
Expression of the homeobox gene GBX2 during chicken development.
Niss, K. and Leutz, A.
Mechanisms of Development 76
(1-2): 151-155.
August 1998
Interleukin-3 promotes proliferation and differentiation of human hematopoietic stem cells but reduces their repopulation potential in NOD/SCID mice.
Nitsche, A., Junghahn, I., Thulke, S., Aumann, J., Radonic, A., Fichtner, I. and Siegert, W.
Stem Cells 21
(2): 236-244.
March 2003
Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer.
Nitsche, U., Rosenberg, R., Balmert, A., Schuster, T., Slotta-Huspenina, J., Herrmann, P., Bader, F.G., Friess, H., Schlag, P.M., Stein, U. and Janssen, K.P.
Annals of Surgery 256
(5): 763-771.
November 2012
CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens.
Nitta, T., Nitta, S., Lei, Y., Lipp, M. and Takahama, Y.
Proceedings of the National Academy of Sciences of the United States of America 106
(40): 17129-17133.
6 October 2009
Efficacy of triple therapies including ionising radiation, agonistic TRAIL antibodies and cisplatin.
Niyazi, M., Marini, P., Daniel, P.T., Humphreys, R., Jendrossek, V. and Belka, C.
Oncology Reports 21
(6): 1455-1460.
June 2009
Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Niyazi, M., Marini, P., Daniel, P.T., Humphreys, R., Jendrossek, V. and Belka, C.
Strahlentherapie und Onkologie 185
(1): 8-18.
January 2009
SMOG 2: A versatile software package for generating structure-based models.
Noel, J.K., Levi, M., Raghunathan, M., Lammert, H., Hayes, R.L., Onuchic, J.N. and Whitford, P.C.
PLoS Computational Biology 12
(3): e1004794.
10 March 2016
Topological reaction coordinate captures the folding transition state ensemble in a pierced lasso protein.
Noel, J.K. and Haglund, E.
Journal of Physical Chemistry B 128
(1): 117-124.
11 January 2024
Polymer-like model to study the dynamics of dynamin filaments on deformable membrane tubes.
Noel, J.K., Noé, F., Daumke, O. and Mikhailov, A.S.
Biophysical Journal 117
(10): 1870-1891.
19 November 2019
How EF-Tu can contribute to efficient proofreading of aa-tRNA by the ribosome.
Noel, J.K. and Whitford, P.C.
Nature Communications 7
: 13314.
31 October 2016
Genetic characterization of primary mediastinal B-cell lymphoma: pathogenesis and patient outcomes.
Noerenberg, D., Briest, F., Hennch, C., Yoshida, K., Hablesreiter, R., Takeuchi, Y., Ueno, H., Staiger, A.M., Ziepert, M., Asmar, F., Locher, B.N., Toth, E., Weber, T., Amini, R.M., Klapper, W., Bouzani, M., Poeschel, V., Rosenwald, A., Held, G., Campo, E., Ishaque, N., Stamatopoulos, K., Kanellis, G., Anagnostopoulos, I., Bullinger, L., Goldschmidt, N., Zinzani, P.L., Bödör, C., Rosenquist, R., Vassilakopoulos, T.P., Ott, G., Ogawa, S. and Damm, F.
Journal of Clinical Oncology 42
(4): 452-466.
1 February 2024
Improvement of paraneoplastic limbic encephalitis after systemic treatment with rituximab in a patient with B-cell chronic lymphocytic leukemia.
Nogai, H., Israel-Willner, H., Zschenderlein, R. and Pezzutto, A.
Case Reports in Hematology 2013
: 958704.
1 August 2013
IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H., Wenzel, S.S., Hailfinger, S., Grau, M., Kaergel, E., Seitz, V., Wollert-Wulf, B., Pfeifer, M., Wolf, A., Frick, M., Dietze, K., Madle, H., Tzankov, A., Hummel, M., Dörken, B., Scheidereit, C., Janz, M., Lenz, P., Thome, M. and Lenz, G.
Blood 122
(13): 2242-2250.
26 September 2013
Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root.
Nolan, T.M., Vukašinović, N., Hsu, C.W., Zhang, J., Vanhoutte, I., Shahan, R., Taylor, I.W., Greenstreet, L., Heitz, M., Afanassiev, A., Wang, P., Szekely, P., Brosnan, A., Yin, Y., Schiebinger, G., Ohler, U., Russinova, E. and Benfey, P.N.
Science 379
(6639): eadf4721.
31 March 2023
Senescent syncytiotrophoblast secretion during early onset preeclampsia.
Nonn, O., Debnath, O., Valdes, D.S., Sallinger, K., Secener, A.K., Fischer, C., Tiesmeyer, S., Nimo, J., Kuenzer, T., Ulrich, J., Maxian, T., Knöfler, M., Karau, P., Bartolomaeus, H., Kroneis, T., Frolova, A., Neuper, L., Haase, N., Malt, A., Müller-Bötticher, N., Kräker, K., Kedziora, S., Forstner, D., Eils, R., Schmidt-Ullrich, R., Haider, S., Verlohren, S., Stern, C., Sugulle, M., Jones, S., Thilaganathan, B., Kaitu'u-Lino, T.J., Tong, S., Huppertz, B., El-Heliebi, A., Staff, A.C., Coscia, F., Müller, D.N., Dechend, R., Gauster, M., Ishaque, N. and Herse, F.
Hypertension
23 October 2024
(In Press)
Maternal angiotensin increases placental leptin in early gestation via an alternative renin-angiotensin system pathway: suggesting a link to preeclampsia.
Nonn, O., Fischer, C., Geisberger, S., El-Heliebi, A., Kroneis, T., Forstner, D., Desoye, G., Staff, A.C., Sugulle, M., Dechend, R., Pecks, U., Kollmann, M., Stern, C., Cartwright, J.E., Whitley, G.S., Thilaganathan, B., Wadsack, C., Huppertz, B., Herse, F. and Gauster, M.
Hypertension 77
(5): 1723-1736.
May 2021
Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial.
Nordlinger, B., Sorbye, H., Glimelius, B., Poston, G.J., Schlag, P.M., Rougier, P., Bechstein, W.O., Primrose, J.N., Walpole, E.T., Finch-Jones, M., Jaeck, D., Mirza, D., Parks, R.W., Collette, L., Praet, M., Bethe, U., Van Cutsem, E., Scheithauer, W. and Gruenberger, T.
Lancet 371
(9617): 1007-1016.
22 March 2008
Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial.
Nordlinger, B., Sorbye, H., Glimelius, B., Poston, G.J., Schlag, P.M., Rougier, P., Bechstein, W.O., Primrose, J.N., Walpole, E.T., Finch-Jones, M., Jaeck, D., Mirza, D., Parks, R.W., Mauer, M., Tanis, E., Van Cutsem, E., Scheithauer, W. and Gruenberger, T.
Lancet Oncology 14
(12): 1208-1215.
November 2013
Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.
Norell, H., Poschke, I., Charo, J., Wei, W.Z., Erskine, C., Piechocki, M.P., Knutson, K.L., Bergh, J., Lidbrink, E. and Kiessling, R.
Journal of Translational Medicine 8
(1): 53.
7 June 2010
ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics.
Norton, M., Ng, A.C., Baird, S., Dumoulin, A., Shutt, T., Mah, N., Andrade-Navarro, M.A., McBride, H.M. and Screaton, R.A.
Science Signaling 7
(310): ra10.
28 January 2014
Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters.
Nouailles, G., Adler, J.M., Pennitz, P., Peidli, S., Teixeira Alves, L.G., Baumgardt, M., Bushe, J., Voss, A., Langenhagen, A., Langner, C., Martin Vidal, R., Pott, F., Kazmierski, J., Ebenig, A., Lange, M.V., Mühlebach, M.D., Goekeri, C., Simmons, S., Xing, N., Abdelgawad, A., Herwig, S., Cichon, G., Niemeyer, D., Drosten, C., Goffinet, C., Landthaler, M., Blüthgen, N., Wu, H., Witzenrath, M., Gruber, A.D., Praktiknjo, S.D., Osterrieder, N., Wyler, E., Kunec, D. and Trimpert, J.
Nature Microbiology 8
(5): 860-874.
May 2023
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.
Nouailles, G., Wyler, E., Pennitz, P., Postmus, D., Vladimirova, D., Kazmierski, J., Pott, F., Dietert, K., Muelleder, M., Farztdinov, V., Obermayer, B., Wienhold, S.M., Andreotti, S., Hoefler, T., Sawitzki, B., Drosten, C., Sander, L.E., Suttorp, N., Ralser, M., Beule, D., Gruber, A.D., Goffinet, C., Landthaler, M., Trimpert, J. and Witzenrath, M.
Nature Communications 12
(1): 4869.
11 August 2021
Generation of a NES-mScarlet red fluorescent reporter human iPSC line for live cell imaging and flow cytometric analysis and sorting using CRISPR-Cas9-mediated gene editing.
Nouri, P., Zimmer, A., Brüggemann, S., Friedrich, R., Kühn, R. and Prakash, N.
Cells 11
(2): 268.
13 January 2022
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
Nowak, M., Suenkel, B., Porras, P., Migotti, R., Schmidt, F., Kny, M., Zhu, X., Wanker, E.E., Dittmar, G., Fielitz, J. and Sommer, T.
Journal of Cell Science 132
(17): jcs233395.
6 September 2019
Aberrant expression of miR-9/9* in myeloid progenitors inhibits neutrophil differentiation by post-transcriptional regulation of ERG.
Nowek, K., Sun, S.M., Bullinger, L., Bindels, E.M.J., Exalto, C., Dijkstra, M.K., van Lom, K., Döhner, H., Erkeland, S.J., Löwenberg, B. and Jongen-Lavrencic, M.
Leukemia 30
(1): 229-37.
January 2016
Expression of a passenger miR-9* predicts favorable outcome in adults with acute myeloid leukemia less than 60 years of age.
Nowek, K., Sun, S.M., Dijkstra, M.K., Bullinger, L., Döhner, H., Erkeland, S.J., Löwenberg, B. and Jongen-Lavrencic, M.
Leukemia 30
(2): 303-9.
February 2016
Familial long-read sequencing increases yield of de novo mutations.
Noyes, M.D., Harvey, W.T., Porubsky, D., Sulovari, A., Li, R., Rose, N.R., Audano, P.A., Munson, K.M., Lewis, A.P., Hoekzema, K., Mantere, T., Graves-Lindsay, T.A., Sanders, A.D., Goodwin, S., Kramer, M., Mokrab, Y., Zody, M.C., Hoischen, A., Korbel, J.O., McCombie, W.R. and Eichler, E.E.
American Journal of Human Genetics 109
(4): 631-646.
7 April 2022
Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.
Nurminen, A., Jaatinen, S., Taavitsainen, S., Högnäs, G., Lesluyes, T., Ansari-Pour, N., Tolonen, T., Haase, K., Koskenalho, A., Kankainen, M., Jasu, J., Rauhala, H., Kesäniemi, J., Nikupaavola, T., Kujala, P., Rinta-Kiikka, I., Riikonen, J., Kaipia, A., Murtola, T., Tammela, T.L., Visakorpi, T., Nykter, M., Wedge, D.C., Van Loo, P. and Bova, G.S.
Genome Medicine 15
(1): 82.
12 October 2023
Age-related gliosis promotes central nervous system lymphoma through CCL19-mediated tumor cell retention.
O'Connor, T., Zhou, X., Kosla, J., Adili, A., Garcia Beccaria, M., Kotsiliti, E., Pfister, D., Johlke, A.L., Sinha, A., Sankowski, R., Schick, M., Lewis, R., Dokalis, N., Seubert, B., Höchst, B., Inverso, D., Heide, D., Zhang, W., Weihrich, P., Manske, K., Wohlleber, D., Anton, M., Hoellein, A., Seleznik, G., Bremer, J., Bleul, S., Augustin, H.G., Scherer, F., Koedel, U., Weber, A., Protzer, U., Förster, R., Wirth, T., Aguzzi, A., Meissner, F., Prinz, M., Baumann, B., Höpken, U.E., Knolle, P.A., von Baumgarten, L., Keller, U. and Heikenwalder, M.
Cancer Cell 36
(3): 250-267.
16 September 2019
Serotype-specific pneumococcal antibodies in breast milk of Gambian women immunized with a pneumococcal polysaccharide vaccine during pregnancy.
Obaro, S.K., Deubzer, H.E., Newman, V.O., Adegbola, R.A., Greenwood, B.M. and Henderson, D.C.
Pediatric Infectious Disease Journal 23
(11): 1023-1029.
November 2004
Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice.
Obenaus, M., Leitão, C., Leisegang, M., Chen, X., Gavvovidis, I., van der Bruggen, P., Uckert, W., Schendel, D.J. and Blankenstein, T.
Nature Biotechnology 33
(4): 402-407.
April 2015
Clinical lessons to be learned from patients developing chronic myeloid leukemia while on immunosuppressive therapy after solid organ transplantation: yet another dase after orthotopic heart transplantation.
Oberender, C., Kleeberg, L., Nienhues, N., Gresse, M., Doerken, B., Riess, H. and le Coutre, P.
Case Reports in Hematology 2014
: 890438.
16 November 2014
Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation.
Obermayer, B., Keilholz, L., Conrad, T., Frentsch, M., Blau, I.W., Vuong, L., Lesch, S., Movasshagi, K., Tietze-Stolley, C., Loyal, L., Henze, L., Penack, O., Stervbo, U., Babel, N., Haas, S., Beule, D., Bullinger, L., Wittenbecher, F. and Na, I.K.
Frontiers in Immunology 14
: 1114368.
10 February 2023
Reconstructing gene regulatory dynamics from high-dimensional single-cell snapshot data.
Ocone, A., Haghverdi, L., Mueller, N.S. and Theis, F.J.
Bioinformatics 31
(12): i89-i96.
15 June 2015
Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Oden, F., Marino, S.F., Brand, J., Scheu, S., Kriegel, C., Olal, D., Takvorian, A., Westermann, J., Yilmaz, B., Hinz, M., Daumke, O., Höpken, U.E., Müller, G. and Lipp, M.
Molecular Oncology 9
(7): 1348-1358.
August 2015
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation.
Oeckinghaus, A., Wegener, E., Welteke, V., Ferch, U., Coel Arslan, S., Ruland, J., Scheidereit, C. and Krappmann, D.
EMBO Journal 26
(22): 4634-4645.
14 November 2007
Histone deacetylase 8 in neuroblastoma tumorigenesis.
Oehme, I., Deubzer, H.E., Wegener, D., Pickert, D., Linke, J.P., Hero, B., Kopp-Schneider, A., Westermann, F., Ulrich, S.M., von Deimling, A., Fischer, M. and Witt, O.
Clinical Cancer Research 15
(1): 91-99.
January 2009
Histone deacetylase 10 promotes autophagy-mediated cell survival.
Oehme, I., Linke, J.P., Böck, B.C., Milde, T., Lodrini, M., Hartenstein, B., Wiegand, I., Eckert, C., Roth, W., Kool, M., Kaden, S., Gröne, H.J., Schulte, J.H., Lindner, S., Hamacher-Brady, A., Brady, N.R., Deubzer, H.E. and Witt, O.
Proceedings of the National Academy of Sciences of the United States of America 110
(28): E2592-E2601.
9 July 2013
Update and European consensus on a patient-centered core outcome set for multiple myeloma in clinical practice and research.
Oerlemans, S., De Rooij, B.H., Bennink, C., Bullinger, L., Broijl, A., D'Agostino, M., Laane, E., Lupo-Stanghellini, M.T., Perrot, A., Wester, R., Cursaru, V., Scheurer, H., Vesseur, J., Dalal, M., Sen, R., Stamm, T., Ludwig, H. and Sonneveld, P.
Haematologica 109
(6): 1956-1959.
June 2024
Morphologic diagnosis of leukaemic B-lymphoproliferative disorders and the role of cyclin D1 expression.
Oertel, J., Kingreen, D., Busemann, C., Stein, H. and Doerken, B.
Journal of Cancer Research and Clinical Oncology 128
(4): 182-188.
April 2002
Epstein-Barr viral load in whole blood of adults with posttransplant lymphoproliferative disorder after solid organ transplantation does not correlate with clinical course.
Oertel, S., Trappe, R.U., Zeidler, K., Babel, N., Reinke, P., Hummel, M., Jonas, S., Papp-Vary, M., Subklewe, M., Doerken, B., Riess, H. and Gaertner, B.
Annals of Hematology 85
: 478-484.
July 2006
Effect of anti-CD 20 antibody rituximab in patients with post-transplant lymphoproliferative disorder (PTLD).
Oertel, S.H., Verschuuren, E., Reinke, P., Zeidler, K., Papp-Vary, M., Babel, N., Trappe, R.U., Jonas, S., Hummel, M., Anagnostopoulos, I., Doerken, B. and Riess, H.B.
American Journal of Transplantation 5
: 2901-2906.
1 December 2005
Abdomineller Vakuumsaugverband beim offenen Abdomen [Abdominal vacuum device with open abdomen].
Oetting, P., Rau, B. and Schlag, P.M.
Chirurg 77
(7): 586-593.
July 2006
Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial.
Oettle, H., Post, S., Neuhaus, P., Gellert, K., Langrehr, J., Ridwelski, K., Schramm, H., Fahlke, J., Zuelke, C., Burkart, C., Gutberlet, K., Kettner, E., Schmalenberg, H., Weigang-Koehler, K., Bechstein, W.O., Niedergethmann, M., Schmidt-Wolf, I., Roll, L., Doerken, B. and Riess, H.
JAMA: Journal of the American Medical Association 297
(3): 267-277.
17 January 2007
Second-line oxaliplatin, folinic acid, and fluorouracil versus folinic acid and fluorouracil alone for gemcitabine-refractory pancreatic cancer : outcomes from the CONKO-003 trial.
Oettle, H., Riess, H., Stieler, J.M., Heil, G., Schwaner, I., Seraphin, J., Goerner, M., Moelle, M., Greten, T.F., Lakner, V., Bischoff, S., Sinn, M., Doerken, B. and Pelzer, U.
Journal of Clinical Oncology 32
(23): 2423-2429.
10 August 2014
A dual role for lkkalpha in tooth development.
Ohazama, A., Hu, Y.L., Schmidt-Ullrich, R., Cao, Y.X., Scheidereit, C., Karin, M. and Sharpe, P.T.
Developmental Cell 6
(2): 219-227.
1 January 2004
Cooperating mechanisms of CXCR5 and CCR7 in development and organization of secondary lymphoid organs.
Ohl, L., Henning, G., Krautwald, S., Lipp, M., Hardtke, S., Bernhardt, G., Pabst, O. and Foerster, R.
Journal of Experimental Medicine 197
(9): 1199-1204.
5 May 2003
CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions.
Ohl, L., Mohaupt, M., Czeloth, N., Hintzen, G., Kiafard, Z., Zwirner, J., Blankenstein, T., Henning, G. and Foerster, R.
Immunity 21
(2): 279-288.
1 August 2004
Identification of core promoter modules in Drosophila and their application in accurate transcription start site prediction.
Ohler, U.
Nucleic Acids Research 34
(20): 5943-5950.
November 2006
Promoter prediction on a genomic scale-the Adh experience.
Ohler, U.
Genome Research 10
(4): 539-542.
April 2000
Interpolated markov chains for eukaryotic promoter recognition.
Ohler, U., Harbeck, S., Niemann, H., Noeth, E. and Reese, M.G.
Bioinformatics 15
(5): 362-369.
May 1999
Computational analysis of core promoters in the Drosophila genome.
Ohler, U., Liao, G.C., Niemann, H. and Rubin, G.M.
Genome Biology 3
(12): RESEARCH0087.
2002
Joint modeling of DNA sequence and physical properties to improve eukaryotic promoter recognition.
Ohler, U., Niemann, H, Liao, G.C. and Rubin, G.M.
Bioinformatics 17 Suppl 1
: S199-206.
2001
Identification and analysis of eukaryotic promoters: recent computational approaches.
Ohler, U. and Niemann, H.
Trends in Genetics 17
(2): 56-60.
February 2001
Recognition of unknown conserved alternatively spliced exons.
Ohler, U., Shomron, N. and Burge, C.B.
PLoS Computational Biology 1
(2): 113-122.
July 2005
Stochastic segment models of eukaryotic promoter regions.
Ohler, U., Stemmer, G., Harbeck, S. and Niemann, H.
Pacific Symposium on Biocomputing
: 380-391.
2000
Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification.
Ohler, U., Yekta, S., Lim, L.P., Bartel, D.P. and Burge, C.B.
RNA 10
(9): 1309-1322.
September 2004
Extracellular purine metabolism is the switchboard of immunosuppressive macrophages and a novel target to treat diseases with macrophage imbalances.
Ohradanova-Repic, A., Machacek, C., Charvet, C., Lager, F., Le Roux, D., Platzer, R., Leksa, V., Mitulovic, G., Burkard, T.R., Zlabinger, G.J., Fischer, M.B., Feuillet, V., Renault, G., Blüml, S., Benko, M., Suchanek, M., Huppa, J.B., Matsuyama, T., Cavaco-Paulo, A., Bismuth, G. and Stockinger, H.
Frontiers in Immunology 9
: 852.
27 April 2018
Chemokine requirements for B cell entry to lymph nodes and Peyers patches.
Okada, T., Ngo, V.N., Ekland, E.H., Foerster, R., Lipp, M., Littman, D.R. and Cyster, J.G.
Journal of Experimental Medicine 196
(1): 65-75.
1 July 2002
Lysine acetylation regulates the interaction between proteins and membranes.
Okada, A.K., Teranishi, K., Ambroso, M.R., Isas, J.M., Vazquez-Sarandeses, E., Lee, J.Y., Melo, A.A., Pandey, P., Merken, D., Berndt, L., Lammers, M., Daumke, O., Chang, K., Haworth, I.S. and Langen, R.
Nature Communications 12
(1): 6466.
9 November 2021
Potential autoregulation of transcription factor PU.1 by an upstream regulatory element.
Okuno, Y., Huang, G., Rosenbauer, F., Evans, E.K., Radomska, H.S., Iwasaki, H., Akashi, K., Moreau-Gachelin, F., Li, Y., Zhang, P., Goettgens, B. and Tenen, D.G.
Molecular and Cellular Biology 25
: 2832-2845.
1 April 2005
Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation.
Olal, D. and Daumke, O.
Cell Reports 14
(9): 2092-2099.
8 March 2016
Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein.
Olal, D., Dick, A., Woods, V.L., Liu, T., Li, S., Devignot, S., Weber, F., Saphire, E.O. and Daumke, O.
Nucleic Acids Research 42
(9): 6025-6037.
14 May 2014
Inclusion of temporal information in single cell transcriptomics.
Olivares-Chauvet, P. and Junker, J.P.
International Journal of Biochemistry and Cell Biology 122
: 105745.
May 2020
58/w mit zunehmender psychomotorischer Verlangsamung und Zephalgien [58/f with increasing psychomotor retardation and headache].
Onken, J.S. and Bullinger, L.
Onkologe 27
: 79-84.
September 2021
Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia.
Opel, D., Schnaiter, A., Dodier, D., Jovanovic, M., Gerhardinger, A., Idler, I., Mertens, D., Bullinger, L., Stilgenbauer, S. and Fulda, S.
International Journal of Cancer 137
(12): 2959-2970.
15 December 2015
Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla, T., Gollasch, B., Kuich, P.H.J.L., Klug, L., Rahn, G., Busjahn, A., Spuler, S., Boschmann, M., Kirwan, J.A., Luft, F.C. and Kempa, S.
Frontiers in Molecular Biosciences 9
: 1042231.
21 December 2022
Towards a more reliable identification of isomeric metabolites using pattern guided retention validation.
Opialla, T., Kempa, S. and Pietzke, M.
Metabolites 10
(11): 457.
12 November 2020
A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Opitz, R., Mueller, M., Reuter, C., Barone, M., Soicke, A., Roske, Y., Piotukh, K., Huy, P., Beerbaum, M., Wiesner, B., Beyermann, M., Schmieder, P., Freund, C., Volkmer, R., Oschkinat, H., Schmalz, H.G. and Kuehne, R.
Proceedings of the National Academy of Sciences of the United States of America 112
(16): 5011-5016.
21 April 2015
Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk/Bik.
Oppermann, M., Geilen, C.C., Fecker, L.F., Gillissen, B., Daniel, P.T. and Eberle, J.
Oncogene 24
: 7369-7380.
4 July 2005
Assessment of complement activation in vivo.
Oppermann, M., Höpken, U. and Götze, O.
Immunopharmacology 24
(2): 119-34.
September 1992
Production of neuroprotective NGF in astrocyte-T helper cell cocultures is upregulated following antigen recognition.
Oren, A., Falk, K., Roetzschke, O., Bechmann, I., Nitsch, R. and Gimsa, U.
Journal of Neuroimmunology 149
(1-2): 59-65.
April 2004
Finding RNA structure in the unstructured RBPome.
Orenstein, Y., Ohler, U. and Berger, B.
BMC Genomics 19
(1): 154.
20 February 2018
I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development.
Orinska, Z., Foeger, N., Huber, M., Marschall, J., Mirghomizadeh, F., Du, X., Scheller, M., Rosenstiel, P., Goldmann, T., Bollinger, A., Beutler, B.A. and Bulfone-Paus, S.
Blood 116
(15): 2665-2675.
14 October 2010
Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.
Orlanski, S., Labi, V., Reizel, Y., Spiro, A., Lichtenstein, M., Levin-Klein, R., Koralov, S.B., Skversky, Y., Rajewsky, K., Cedar, H. and Bergman, Y.
Proceedings of the National Academy of Sciences of the United States of America 113
(18): 5018-5023.
3 May 2016
High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma.
Orth, M.F., Hölting, T.L.B., Dallmayer, M., Wehweck, F.S., Paul, T., Musa, J., Baldauf, M.C., Surdez, D., Delattre, O., Knott, M.M.L., Romero-Pérez, L., Kasan, M., Cidre-Aranaz, F., Gerke, J.S., Ohmura, S., Li, J., Marchetto, A., Henssen, A.G., Özen, Ö., Sugita, S., Hasegawa, T., Kanaseki, T., Bertram, S., Dirksen, U., Hartmann, W., Kirchner, T. and Grünewald, T.G.P.
Cancers 12
(3): 644.
10 March 2020
Improved treatment of MT-3 breast cancer and brain metastases in a mouse xenograft by LRP-targeted oxaliplatin liposomes.
Orthmann, A., Peiker, L., Fichtner, I., Hoffmann, A., Hilger, R.A. and Zeisig, R.
Journal of Biomedical Nanotechnology 12
(1): 56-68.
January 2016
Impact of membrane properties on uptake and transcytosis of colloidal nanocarriers across an epithelial cell barrier model.
Orthmann, A., Zeisig, R., Koklic, T., Sentjurc, M., Wiesner, B., Lemm, M. and Fichtner, I.
Journal of Pharmaceutical Sciences 99
(5): 2423-2433.
May 2010
Treatment of experimental brain metastasis with MTO-liposomes: impact of fluidity and LRP-targeting on the therapeutic result.
Orthmann, A., Zeisig, R., Suess, R., Lorenz, D., Lemm, M. and Fichtner, I.
Pharmaceutical Research 29
(7): 1949-1959.
July 2012
Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
Ortiz, M.V., Ahmed, S., Burns, M., Henssen, A.G., Hollmann, T.J., MacArthur, I., Gunasekera, S., Gaewsky, L., Bradwin, G., Ryan, J., Letai, A., He, Y., Naranjo, A., Chi, Y.Y., LaQuaglia, M., Heaton, T., Cifani, P., Dome, J.S., Gadd, S., Perlman, E., Mullen, E., Steen, H. and Kentsis, A.
JCI Insight 4
(15): e127098.
8 August 2019
Using cited references to improve the retrieval of related biomedical documents.
Ortuno, F.M., Rojas, I., Andrade-Navarro, M.A. and Fontaine, J.F.
BMC Bioinformatics 14
: 113.
27 March 2013
Expression of C5a receptor in mouse brain: role in signal transduction and neurodegeneration.
Osaka, H., McGinty, A., Höpken, U.E., Lu, B., Gerard, C. and Pasinetti, G.M.
Neuroscience 88
(4): 1073-1082.
February 1999
E2F-dependent regulation of human MYC: trans-activation by cyclins D1 and A overrides tumour suppressor protein functions.
Oswald, F., Lovec, H., Moeroey, T. and Lipp, M.
Oncogene 9
(7): 2029-2036.
July 1994
The B-cell antigen receptor integrates adaptive and innate immune signals.
Otipoby, K.L., Waisman, A., Derudder, E., Srinivasan, L., Franklin, A. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 112
(39): 12145-12150.
29 September 2015
Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas.
Otto, T., Birchmeier, W., Schmidt, U., Hinke, A., Schipper, J., Ruebben, H. and Raz, A.
Cancer Research 54
(12): 3120-3123.
15 June 1994
Evaluation of efficient chemoembolization mixtures by magnetic resonance imaging therapy monitoring: an experimental study on the vx2 tumor in the rabbit liver.
Paeuser, S., Wagner, S., Lippmann, M., Pohlen, U., Reszka, R., Wolf, K.J. and Berger, G.
Cancer Research 56
(8): 1863-1867.
15 April 1996
Oncoleaking: use of the pore-forming clostridium perfringens enterotoxin (CPE) for suicide gene therapy.
Pahle, J., Aumann, J., Kobelt, D. and Walther, W.
Methods in Molecular Biology 1317
: 69-85.
2015
Effective oncoleaking treatment of pancreatic cancer by claudin-targeted suicide gene therapy with Clostridium perfringens enterotoxin (CPE).
Pahle, J., Kobelt, D., Aumann, J., Behrens, D., Daberkow, O., Mokritzkij, M., Piontek, J., Stein, U. and Walther, W.
Cancers 13
(17): 4393.
1 September 2021
Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy.
Pahle, J., Menzel, L., Niesler, N., Kobelt, D., Aumann, J., Rivera, M. and Walther, W.
BMC Cancer 17
(1): 129.
13 February 2017
Bacterial toxins for oncoleaking suicidal cancer gene therapy.
Pahle, J. and Walther, W.
Recent Results in Cancer Research 209
: 95-110.
2016
The genome of the simian and human malaria parasite Plasmodium knowlesi.
Pain, A., Boehme, U., Berry, A.E., Mungall, K., Finn, R.D., Jackson, A.P., Mourier, T., Mistry, J., Pasini, E.M., Aslett, M.A., Balasubrammaniam, S., Borgwardt, K., Brooks, K., Carret, C., Carver, T.J., Cherevach, I., Chillingworth, T., Clark, T.G., Galinski, M.R., Hall, N., Harper, D., Harris, D., Hauser, H., Ivens, A., Janssen, C.S., Keane, T., Larke, N., Lapp, S., Marti, M., Moule, S., Meyer, I.M., Ormond, D., Peters, N., Sanders, M., Sanders, S., Sargeant, T.J., Simmonds, M., Smith, F., Squares, R., Thurston, S., Tivey, A.R., Walker, D., White, B., Zuiderwijk, E., Churcher, C., Quail, M.A., Cowman, A.F., Turner, C.M.R., Rajandream, MA, Kocken, C.H.M., Thomas, A.W., Newbold, C.I., Barrell, B.G. and Berriman, M.
Nature 455
(7214): 799-803.
9 October 2008
The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.
Pajtler, K.W., Sadowski, N., Ackermann, S., Althoff, K., Schönbeck, K., Batzke, K., Schäfers, S., Odersky, A., Heukamp, L., Astrahantseff, K., Künkele, A., Deubzer, H.E., Schramm, A., Sprüssel, A., Thor, T., Lindner, S., Eggert, A., Fischer, M. and Schulte, J.H.
Oncotarget 8
(4): 6730-6741.
24 January 2017
C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Pal, R., Janz, M., Galson, D.L., Gries, M., Li, S., Johrens, K., Anagnostopoulos, I., Doerken, B., Mapara, M.Y., Borghesi, L., Kardava, L., Roodman, G.D., Milcarek, C. and Lentzsch, S.
Blood 114
(18): 3890-3898.
29 October 2009
Translation of circRNAs.
Pamudurti, N.R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., Shenzis, S., Samson, M., Dittmar, G., Landthaler, M., Chekulaeva, M., Rajewsky, N. and Kadener, S.
Molecular Cell 66
(1): 9-21.
6 April 2017
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Pan, X., AbdulJabbar, K., Coelho-Lima, J., Grapa, A.I., Zhang, H., Cheung, A.H.K., Baena, J., Karasaki, T., Wilson, C.R., Sereno, M., Veeriah, S., Aitken, S.J., Hackshaw, A., Nicholson, A.G., Jamal-Hanjani, M., Swanton, C., Yuan, Y., Le Quesne, J. and Moore, D.A.
Nature Cancer 5
(2): 347-363.
February 2024
Clinical implications and dynamics of clonal hematopoiesis in anti-CD19 CAR T-cell treated patients.
Panagiota, V., Kerschbaum, J.F., Penack, O., Stein, C.M., Arends, C.M., Koenecke, C., Strzelecka, P.M., Kloos, A., Wiegand, L., Lasch, A., Altwasser, R., Halik, A., Gabdoulline, R., Thomson, J., Weibl, K., Franke, G.N., Berger, C., Hasenkamp, J., Ayuk, F., Na, I.K., Beutel, G., Keller, U., Bullinger, L., Wulf, G.G., Kröger, N., Vucinic, V., Heuser, M. and Damm, F.
HemaSphere 7
(10): e957.
October 2023
Immunotherapy of B cell non-Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model.
Panjideh, H., Mueller, G., Koch, M., Wilde, F., Scheu, S., Moldenhauer, G. and Lipp, M.
International Journal of Cancer 135
(11): 2623-2632.
1 December 2014
Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro.
Panzenboeck, B., Bartunek, P., Mapara, M.Y. and Zenke, M.
Blood 92
(10): 3658-3668.
15 November 1998
Assessment of genomic instability in breast cancer and uveal melanoma by random amplified polymorphic DNA analysis.
Papadopoulos, S., Benter, T., Anastassiou, G., Pape, M., Gerhard, S., Bornfeld, N., Ludwig, W.D. and Doerken, B.
International Journal of Cancer 99
(2): 193-200.
10 May 2002
Genomic classification and prognosis in acute myeloid leukemia.
Papaemmanuil, E., Gerstung, M., Bullinger, L., Gaidzik, V.I., Paschka, P., Roberts, N.D., Potter, N.E., Heuser, M., Thol, F., Bolli, N., Gundem, G., Van Loo, P., Martincorena, I., Ganly, P., Mudie, L., McLaren, S., O'Meara, S., Raine, K., Jones, D.R., Teague, J.W., Butler, A.P., Greaves, M.F., Ganser, A., Döhner, K., Schlenk, R.F., Döhner, H. and Campbell, P.J.
New England Journal of Medicine 374
(23): 2209-2221.
12 July 2016
Landmark constrained non-parametric image registration with isotropic tolerances.
Papenberg, N., Olesch, J., Lange, T., Schlag, P.M. and Fischer, B.
Informatik aktuell
: 122-126.
2009
MDC1 maintains active elongation complexes of RNA polymerase II.
Pappas, G., Munk, S.H.N., Watanabe, K., Thomas, Q., Gál, Z., Gram, H.H., Lee, M.H., Gómez-Cabello, D., Kanellis, D.C., Olivares-Chauvet, P., Larsen, D.H., Gregersen, L.H., Maya-Mendoza, A., Galanos, P. and Bartek, J.
Cell Reports 42
(1): 111979.
31 January 2023
GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway.
Park, A.Y., Leney-Greene, M., Lynberg, M., Gabrielski, J.Q., Xu, X., Schwarz, B., Zheng, L., Balasubramaniyam, A., Ham, H., Chao, B., Zhang, Y., Matthews, H.F., Cui, J., Yao, Y., Kubo, S., Chanchu, J.M., Morawski, A.R., Cook, S.A., Jiang, P., Ravell, J.C., Cheng, Y.H., George, A., Faruqi, A., Pagalilauan, A.M., Bergerson, J.R.E., Ganesan, S., Chauvin, S.D., Aluri, J., Edwards-Hicks, J., Bohrnsen, E., Tippett, C., Omar, H., Xu, L., Butcher, G.W., Pascall, J., Karakoc-Aydiner, E., Kiykim, A., Maecker, H., Tezcan, İ., Esenboga, S., Heredia, R.J., Akata, D., Tekin, S., Kara, A., Kuloglu, Z., Unal, E., Kendirli, T., Dogu, F., Karabiber, E., Atkinson, T.P., Cochet, C., Filhol, O., Bosio, C.M., Davis, M.M., Lifton, R.P., Pearce, E.L., Daumke, O., Aytekin, C., Şahin, G.E., Aksu, A.Ü., Uzel, G., Koneti Rao, V., Sari, S., Boztug, K., Cagdas, D., Haskologlu, S., Ikinciogullari, A., Schwefel, D., Vilarinho, S., Baris, S., Ozen, A., Su, H.C. and Lenardo, M.J.
Nature Immunology 25
(2): 282-293.
February 2024
Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.
Park, T.J., Reznick, J., Peterson, B.L., Blass, G., Omerbašić, D., Bennett, N.C., Kuich, P.H.J.L., Zasada, C., Browe, B.M., Hamann, W., Applegate, D.T., Radke, M.H., Kosten, T., Lutermann, H., Gavaghan, V., Eigenbrod, O., Bégay, V., Amoroso, V. G., Govind, V., Minshall, R.D., Smith, E.S.J., Larson, J., Gotthardt, M., Kempa, S. and Lewin, G.R.
Science 356
(6335): 307-311.
21 April 2017
The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery.
Parry, T.J., Theisen, J.W.M., Hsu, J.Y., Wang, Y.L., Corcoran, D.L., Eustice, M., Ohler, U. and Kadonaga, J.T.
Genes & Development 24
(18): 2013-2018.
15 September 2010
Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG).
Paschka, P., Du, J., Schlenk, R.F., Gaidzik, V.I., Bullinger, L., Corbacioglu, A., Späth, D., Kayser, S., Schlegelberger, B., Krauter, J., Ganser, A., Köhne, C.H., Held, G., von Lilienfeld-Toal, M., Kirchen, H., Rummel, M., Götze, K., Horst, H.A., Ringhoffer, M., Lübbert, M., Wattad, M., Salih, H.R., Kündgen, A., Döhner, H. and Döhner, K.
Blood 121
(1): 170-7.
3 January 2013
ASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study Group.
Paschka, P., Schlenk, R.F., Gaidzik, V.I., Herzig, J.K., Aulitzky, T., Bullinger, L., Späth, D., Teleanu, V., Kündgen, A., Köhne, C.H., Brossart, P., Held, G., Horst, H.A., Ringhoffer, M., Götze, K., Nachbaur, D., Kindler, T., Heuser, M., Thol, F., Ganser, A., Döhner, H. and Döhner, K.
Haematologica 100
(3): 324-330.
March 2015
Adding dasatinib to intensive treatment in core-binding factor acute myeloid leukemia-results of the AMLSG 11-08 trial.
Paschka, P., Schlenk, R.F., Weber, D., Benner, A., Bullinger, L., Heuser, M., Gaidzik, V.I., Thol, F., Agrawal, M., Teleanu, V., Lübbert, M., Fiedler, W., Radsak, M., Krauter, J., Horst, H.A., Greil, R., Mayer, K., Kündgen, A., Martens, U., Heil, G., Salih, H.R., Hertenstein, B., Schwänen, C., Wulf, G., Lange, E., Pfreundschuh, M., Ringhoffer, M., Girschikofsky, M., Heinicke, T., Kraemer, D., Göhring, G., Ganser, A., Döhner, K. and Döhner, H.
Leukemia 32
(7): 1621-1630.
July 2018
Geographical distribution of hantaviruses in Thailand and potential human health significance of Thailand virus.
Pattamadilok, S., Lee, B.H., Kumperasart, S., Yoshimatsu, K., Okumura, M., Nakamura, I., Araki, K., Khoprasert, Y., Dangsupa, P., Panlar, P., Jandrig, B., Krueger, D.H., Klempa, B., Jaekel, T., Schmidt, J., Ulrich, R., Kariwa, H. and Arikawa, J.
American Journal of Tropical Medicine and Hygiene 75
(5): 994-1002.
November 2006
The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells.
Patzke, C., Max, K.E., Behlke, J., Schreiber, J., Schmidt, H., Dorner, A.A., Kroeger, S., Henning, M., Otto, A., Heinemann, U. and Rathjen, F.G.
Journal of Neuroscience 30
(8): 2897-2910.
24 February 2010
Transcriptional heterogeneity and lineage commitment in myeloid progenitors.
Paul, F., Arkin, Y., Giladi, A., Jaitin, D.A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., David, E., Cohen, N., Lauridsen, F.K.B., Haas, S., Schlitzer, A., Mildner, A., Ginhoux, F., Jung, S., Trumpp, A., Porse, B.T., Tanay, A. and Amit, I.
Cell 163
(7): 1663-1677.
17 December 2015
Quantitative GTPase affinity purification identifies Rho family protein interaction partners.
Paul, F., Zauber, H., von Berg, L., Rocks, O., Daumke, O. and Selbach, M.
Molecular & Cellular Proteomics 16
(1): 73-85.
1 January 2017
The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
Paulmann, C., Spallek, R., Karpiuk, O., Heider, M., Schäffer, I., Zecha, J., Klaeger, S., Walzik, M., Öllinger, R., Engleitner, T., Wirth, M., Keller, U., Krönke, J., Rudelius, M., Kossatz, S., Rad, R., Kuster, B. and Bassermann, F.
EMBO Journal 41
(20): e110871.
17 October 2022
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.
Pavri, R., Gazumyan, A., Jankovic, M., Di Virgilio, M., Klein, I., Ansarah-Sobrinho, C., Resch, W., Yamane, A., Reina San-Martin, B., Barreto, V., Nieland, T.J., Root, D.E., Casellas, R. and Nussenzweig, M.C.
Cell 143
(1): 122-133.
1 October 2010
Increased abundance of Firmicutes and depletion of Bacteroidota predicts poor outcome in chronic lymphocytic leukemia.
Paziewska, M., Szelest, Mo., Kiełbus, M., Masternak, M., Zaleska, J., Wawrzyniak, E., Kotkowska, A., Siemieniuk-Ryś, M., Morawska, M., Kalicińska, E., Jabłonowska, P., Wróbel, T., Wolska-Washer, A., Błoński, J.Z., Robak, T., Bullinger, L. and Giannopoulos, K.
Oncology letters 28
(5): 552.
November 2024
Induction of cellular immunity in chimpanzees to human tumor associated antigen mucin by vaccination with MUC-1 cDNA-transfected Epstein-Barr virus-immortalized autologous B cells.
Pecher, G. and Finn, O.J.
Proceedings of the National Academy of Sciences of the United States of America 93
(4): 1699-1704.
20 February 1996
An evolutionary model for protein-coding regions with conserved RNA structure.
Pedersen, J.S., Forsberg, R., Meyer, I.M. and Hein, J.
Molecular Biology and Evolution 21
(10): 1913-1922.
October 2004
A comparative method for finding and folding RNA secondary structures within protein-coding regions.
Pedersen, J.S., Meyer, I.M., Forsberg, R., Simmonds, P. and Hein, J.
Nucleic Acids Research 32
(16): 4925-4936.
24 September 2004
Single-cell-resolved interspecies comparison shows a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19.
Peidli, S., Nouailles, G., Wyler, E., Adler, J.M., Kunder, S., Voß, A., Kazmierski, J., Pott, F., Pennitz, P., Postmus, D., Teixeira Alves, L.G., Goffinet, C., Gruber, A.D., Blüthgen, N., Witzenrath, M., Trimpert, J., Landthaler, M. and Praktiknjo, S.D.
Cell Reports 43
(6): 114328.
25 June 2024
Multiplexed quantification of four neuroblastoma DNA targets in a single droplet digital PCR reaction.
Peitz, C., Sprüssel, A., Linke, R.B., Astrahantseff, K., Grimaldi, M., Schmelz, K., Toedling, J., Schulte, J.H., Fischer, M., Messerschmidt, C., Beule, D., Keilholz, U., Eggert, A., Deubzer, H.E. and Lodrini, M.
Journal of Molecular Diagnostics 22
(11): 1309-1323.
November 2020
Identification of gene expression-based prognostic markers in the hematopoietic stem cells of patients with myelodysplastic syndromes.
Pellagatti, A., Benner, A., Mills, K.I., Cazzola, M., Giagounidis, A., Perry, J., Malcovati, L., Della Porta, M.G., Jädersten, M., Verma, A., McDonald, E.J., Killick, S., Hellström-Lindberg, E., Bullinger, L., Wainscoat, J.S. and Boultwood, J.
Journal of Clinical Oncology 31
(28): 3557-3564.
1 October 2013
Efficient transcription of an immunoglobulin kappa promoter requires specific sequence elements overlapping with and downstream of the transcriptional start site.
Pelletier, M.R., Hatada, E.N., Scholz, G. and Scheidereit, C.
Nucleic Acids Research 25
(20): 3995-4003.
15 October 1997
A novel inhibitory domain of Helicobacter pylori protein CagA reduces CagA effects on host cell biology.
Pelz, C., Steininger, S., Weiss, C., Coscia, F. and Vogelmann, R.
Journal of Biological Chemistry 286
(11): 8999-9008.
18 March 2011
Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study.
Pelzer, U., Arnold, D., Govercin, M., Stieler, J., Doerken, B., Riess, H. and Oettle, H.
BMC Cancer 10
(1): 86.
9 March 2010
First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group.
Pelzer, U., Arnold, D., Reitzig, P., Herrenberger, J., Korsten, F.W., Kindler, M., Stieler, J., Doerken, B., Riess, H. and Oettle, H.
Cancer Chemotherapy and Pharmacology 68
(5): 1173-1178.
November 2011
Value of carbohydrate antigen 19-9 in predicting response and therapy control in patients with metastatic pancreatic cancer undergoing first-line therapy.
Pelzer, U., Hilbig, A., Sinn, M., Stieler, J., Bahra, M., Doerken, B. and Riess, H.
Frontiers in Oncology 3
: 155.
June 2013
Intensified chemotherapy and simultaneous treatment with heparin in outpatients with pancreatic cancer - the CONKO 004 pilot trial.
Pelzer, U., Hilbig, A., Stieler, J.M., Bahra, M., Sinn, M., Gebauer, B., Doerken, B. and Riess, H.
BMC Cancer 14
(1): 204.
19 March 2014
Blood group determinates incidence for pancreatic cancer in Germany.
Pelzer, U., Klein, F., Bahra, M., Sinn, M., Doerken, B., Neuhaus, P., Meyer, O. and Riess, H.
Frontiers in Physiology 4
: 118.
24 May 2013
Efficacy of prophylactic low-molecular weight heparin for ambulatory patients with advanced pancreatic cancer: outcomes from the CONKO-004 trial.
Pelzer, U., Opitz, B., Deutschinoff, G., Stauch, M., Reitzig, P.C., Hahnfeld, S., Mueller, L., Grunewald, M., Stieler, J.M., Sinn, M., Denecke, T., Bischoff, S., Oettle, H., Doerken, B. and Riess, H.
Journal of Clinical Oncology 33
(18): 2028-2034.
20 June 2015
Best supportive care (BSC) versus oxaliplatin, folinic acid and 5-fluorouracil (OFF) plus BSC in patients for second-line advanced pancreatic cancer: A phase III-study from the German CONKO-study group.
Pelzer, U., Schwaner, I., Stieler, J., Adler, M., Seraphin, J., Doerken, B., Riess, H. and Oettle, H.
European Journal of Cancer 47
(11): 1676-1681.
July 2011
Second-line therapy in refractory pancreatic cancer. results of a phase II study.
Pelzer, U., Stieler, J., Roll, L., Hilbig, A., Doerken, B., Riess, H. and Oettle, H.
Onkologie 32
(3): 99-102.
March 2009
Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth.
Penack, O., Henke, E., Suh, D., King, C.G., Smith, O.M., Na, I.K., Holland, A.M., Ghosh, A., Lu, S.X., Jenq, R.R., Liu, C., Murphy, G.F., Lu, T.T., May, C., Scheinberg, D.A., Gao, D.C., Mittal, V., Heller, G., Benezra, R. and van den Brink, M.R.M.
Journal of the National Cancer Institute 102
(12): 894-908.
16 June 2010
NOD2 regulates hematopoietic cell function during graft-versus-host disease.
Penack, O., Smith, O.M., Cunningham-Bussel, A., Liu, X., Rao, U., Yim, N., Na, I.K., Holland, A.M., Ghosh, A., Lu, S.X., Jenq, R.R., Liu, C., Murphy, G.F., Brandl, K. and van den Brink, M.R.M.
Journal of Experimental Medicine 206
(10): 2101-2110.
28 September 2009
Protocol to dissociate healthy and infected murine- and hamster-derived lung tissue for single-cell transcriptome analysis.
Pennitz, P., Goekeri, C., Trimpert, J., Wyler, E., Ebenig, A., Weissfuss, C., Mühlebach, M.D., Witzenrath, M. and Nouailles, G.
STAR Protocols 4
(1): 101957.
17 March 2023
A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics.
Pennitz, P., Kirsten, H., Friedrich, V.D., Wyler, E., Goekeri, C., Obermayer, B., Heinz, G.A., Mashreghi, M.F., Büttner, M., Trimpert, J., Landthaler, M., Suttorp, N., Hocke, A.C., Hippenstiel, S., Tönnies, M., Scholz, M., Kuebler, W.M., Witzenrath, M., Hoenzke, K. and Nouailles, G.
European Respiratory Review 31
(165): 220056.
30 September 2022
Tracking rare single donor and recipient immune and leukemia cells after allogeneic hematopoietic cell transplantation using mitochondrial DNA mutations.
Penter, L., Cieri, N., Maurer, K., Kwok, M., Lyu, H., Lu, W.S., Oliveira, G., Gohil, S.H., Leshchiner, I., Lareau, C.A., Ludwig, L.S., Neuberg, D.S., Kim, H.T., Li, S., Bullinger, L., Ritz, J., Getz, G., Garcia, J.S., Soiffer, R.J., Livak, K.J. and Wu, C.J.
Blood Cancer Discovery 5
(6): 442-459.
1 November 2024
Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer.
Penter, L., Dietze, K., Ritter, J., Lammoglia Cobo, M.F., Garmshausen, J., Aigner, F., Bullinger, L., Hackstein, H., Wienzek-Lischka, S., Blankenstein, T., Hummel, M., Dornmair, K. and Hansmann, L.
OncoImmunology 8
(6): e1586409.
24 March 2019
Longitudinal single-cell dynamics of chromatin accessibility and mitochondrial mutations in chronic lymphocytic leukemia mirror disease history.
Penter, L., Gohil, S.H., Lareau, C., Ludwig, L.S., Parry, E.M., Huang, T., Li, S., Zhang, W., Livitz, D., Leshchiner, I., Parida, L., Getz, G., Rassenti, L.Z., Kipps, T.J., Brown, J.R., Davids, M.S., Neuberg, D.S., Livak, K.J., Sankaran, V.G. and Wu, C.J.
Cancer Discovery 11
(12): 3048-3063.
December 2021
Mitochondrial DNA mutations as natural barcodes for lineage tracing of murine tumor models.
Penter, L., Ten Hacken, E., Southard, J., Lareau, C., Ludwig, L.S., Li, S., Neuberg, D.S., Livak, K.J. and Wu, C.J.
Cancer Research 83
(5): 667-672.
1 March 2023
Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts.
Perez, C., Jukica, A., Listopad, J.J., Anders, K., Kühl, A.A., Loddenkemper, C., Blankenstein, T. and Charo, J.
International Journal of Cancer 137
(2): 359-371.
15 July 2014
Towards completion of the Earth's proteome.
Perez-Iratxeta, C., Palidwor, G. and Andrade-Navarro, M.A.
EMBO Reports 8
(12): 1135-1141.
1 December 2007
Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation.
Perotti, C., Liu, R., Parusel, C., Boecher, N., Schultz, J., Bork, P., Pfitzner, E., Groner, B. and Shemanko, C.
Breast Cancer Research 10
(6): R94.
13 November 2008
Simple derivation of transgene-free iPS cells by a dual recombinase approach.
Pertek, A., Meier, F., Irmler, M., Beckers, J., Skylaki, S., Endele, M., Wurst, W., Prakash, N. and Kühn, R.
Molecular Biotechnology 56
(8): 697-713.
August 2014
Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.
Peterson, K.A., Nishi, Y., Ma, W., Vedenko, A., Shokri, L., Zhang, X., McFarlane, M., Baizabal, J.M., Junker, J.P., van Oudenaarden, A., Mikkelsen, T., Bernstein, B.E., Bailey, T.L., Bulyk, M.L., Wong, W.H. and McMahon, A.P.
Genes & Development 26
(24): 2802-2816.
15 December 2012
Adult spinal cord radial glia display a unique progenitor phenotype.
Petit, A., Sanders, A.D., Kennedy, T.E., Tetzlaff, W., Glattfelder, K.J., Dalley, R.A., Puchalski, R.B., Jones, A.R. and Roskams, A.J.
PLoS ONE 6
(9): e24538.
12 September 2011
Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
Petrakis, S., Rasko, T., Russ, J., Friedrich, R.P., Stroedicke, M., Riechers, S.P., Muehlenberg, K., Moeller, A., Reinhardt, A., Vinayagam, A., Schaefer, M.H., Boutros, M., Tricoire, H., Andrade-Navarro, M.A. and Wanker, E.E.
PLoS Genetics 8
(8): e1002897.
16 August 2012
Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
Petrakis, S., Schaefer, M.H., Wanker, E.E. and Andrade-Navarro, M.A.
BioEssays 35
(6): 503-507.
June 2013
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Petretti, T., Kemmner, W., Schulze, B. and Schlag, P.M.
Gut 46
(3): 359-366.
March 2000
The protein expression landscape of the Arabidopsis root.
Petricka, J.J., Schauer, M.A., Megraw, M., Breakfield, N.W., Thompson, J.W., Georgiev, S., Soderblom, E.J., Ohler, U., Moseley, M.A., Grossniklaus, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 109
(18): 6811-6818.
1 May 2012
Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles.
Petrova, V.N., Sawatsky, B., Han, A.X., Laksono, B.M., Walz, L., Parker, E., Pieper, K., Anderson, C.A., de Vries, R.D., Lanzavecchia, A., Kellam, P., von Messling, V., de Swart, R.L. and Russell, C.A.
Science Immunology 4
(41): eaay6125.
1 November 2019
Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Petrović, S., Roske, Y., Rami, B., Phan, M.H.Q., Panakova, D. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 120
(4): e2208941120.
24 January 2023
Treatment with ribociclib shows favourable immunomodulatory effects in patients with hormone receptor-positive breast cancer-findings from the RIBECCA trial.
Peuker, C.A., Yaghobramzi, S., Grunert, C., Keilholz, L, Gjerga, E., Hennig, S., Schaper, S., Na, I.K., Keller, U., Brucker, S., Decker, T., Fasching, P., Fehm, T., Janni, W., Kümmel, S., Schneeweiss, A., Schuler, M., Lüftner, D. and Busse, A.
European Journal of Cancer 162
: 45-55.
February 2022
Imaging activation of two Ras isoforms simultaneously in a single cell.
Peyker, A., Rocks, O. and Bastiaens, P.I.
ChemBioChem 6
(1): 78-85.
January 2005
Mutations affecting the actin regulator WD repeat-containing protein 1 lead to aberrant lymphoid immunity.
Pfajfer, L., Mair, N.K, Jiménez-Heredia, R., Genel, F., Gulez, N., Ardeniz, Ö., Hoeger, B., Bal, S.K., Madritsch, C., Kalinichenko, A., Chandra Ardy, R., Gerçeker, B., Rey-Barroso, J., Ijspeert, H., Tangye, S.G., Simonitsch-Klupp, I., Huppa, J.B., van der Burg, M., Dupré, L. and Boztug, K.
Journal of Allergy and Clinical Immunology 142
(5): 1589-1604.e11.
November 2018
Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes.
Pfeifer, M., Zheng, B., Erdmann, T., Koeppen, H., McCord, R., Grau, M., Staiger, A., Chai, A., Sandmann, T., Madle, H., Doerken, B., Chu, Y.W., Chen, A.I., Lebovic, D., Salles, G.A., Czuczman, M.S., Palanca-Wessels, M.C., Press, O.W., Advani, R., Morschhauser, F., Cheson, B.D., Lenz, P., Ott, G., Polson, A.G., Mundt, K.E. and Lenz, G.
Leukemia 29
(7): 1578-1586.
July 2015
PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer, M., Grau, M., Lenze, D., Wenzel, S.S., Wolf, A., Wollert-Wulf, B., Dietze, K., Nogai, H., Storek, B., Madle, H., Dörken, B., Janz, M., Dirnhofer, S., Lenz, P., Hummel, M., Tzankov, A. and Lenz, G.
Proceedings of the National Academy of Sciences of the United States of America 110
(30): 12420-12425.
23 July 2013
A complex of Htm1 and the oxidoreductase Pdi1 accelerates degradation of misfolded glycoproteins.
Pfeiffer, A., Stephanowitz, H., Krause, E., Volkwein, C., Hirsch, C., Jarosch, E. and Sommer, T.
Journal of Biological Chemistry 291
(23): 12195-12207.
3 June 2016
A RAS-independent biomarker panel to reliably predict response to MEK inhibition in colorectal cancer.
Pfohl, U., Loskutov, J., Bashir, S., Kühn, R., Herter, P., Templin, M., Mamlouk, S., Belanov, S., Linnebacher, M., Bürtin, F., Vetter, M., Reinhard, C., Wedeken, L. and Regenbrecht, C.R.A.
Cancers 14
(13): 3252.
1 July 2022
Engineering, decoding and systems-level characterization of chimpanzee cytomegalovirus.
Phan, Q.V., Bogdanow, B., Wyler, E., Landthaler, M., Liu, F., Hagemeier, C. and Wiebusch, L.
PLoS Pathogens 18
(1): e1010193.
4 January 2022
Consortium study on 1280 breast carcinomas: Allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters.
Phelan, C.M., Borg, A., Cuny, M., Crichton, D.N., Baldersson, T., Andersen, T.I., Caligo, M.A., Lidereau, R., Lindblom, A., Seitz, S., Kelsell, D., Hamann, K., Rio, P., Thorlacius, S., Papp, J., Olah, E., Ponder, B., Bignon, Y.J., Scherneck, S., Barkardottir, R., Borresen-Dale, A.L., Eyfjoerd, J., Theillet, C., Thompson, A.M., Devilee, P. and Larsson, C.
Cancer Research 58
(5): 1004-1012.
1 March 1998
In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma.
Philipp-Abbrederis, K., Herrmann, K., Knop, S., Schottelius, M., Eiber, M., Lückerath, K., Pietschmann, E., Habringer, S., Gerngroß, C., Franke, K., Rudelius, M., Schirbel, A., Lapa, C., Schwamborn, K., Steidle, S., Hartmann, E., Rosenwald, A., Kropf, S., Beer, A.J., Peschel, C., Einsele, H., Buck, An.K., Schwaiger, M., Götze, K., Wester, H.J. and Keller, U.
EMBO Molecular Medicine 7
(4): 477-487.
1 April 2015
H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma.
Phoyen, S., Sanpavat, A., Ma-on, C., Stein, U., Hirankarn, N., Tangkijvanich, P., Jindatip, D., Whongsiri, P. and Boonla, C.
Heliyon 9
(12): e22589.
December 2023
Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.
Piaggio, E., Mars, L.T., Cassan, C., Cabarrocas, J., Hofstätter, M., Desbois, S., Bergereau, E., Roetzschke, O., Falk, K. and Liblau, R.S.
Proceedings of the National Academy of Sciences of the United States of America 104
(22): 9393-9398.
29 May 2007
In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.
Pichorner, A., Sack, U., Kobelt, D., Kelch, I., Arlt, F., Smith, J., Walther, W., Schlag, P.M. and Stein, U.
Clinical and Experimental Metastasis 29
(6): 573-583.
August 2012
Pontine tegmental cap dysplasia in an extremely preterm infant and review of the literature.
Picker-Minh, S., Hartenstein, S., Proquitte, H., Froehler, S., Raile, V., Kraemer, N., Apeshiotis, S., Leipoldt, M., Kalache, K.D., Morris-Rosendahl, D., Boltshauser, E., Chen, W. and Kaindl, A.M.
Journal of Child Neurology 32
(3): 334-340.
March 2017
The VEGF receptor, neuropilin-1, represents a promising novel target for chronic lymphocytic leukemia patients.
Piechnik, A., Dmoszynska, A., Omiotek, M., Mlak, R., Kowal, M., Stilgenbauer, S., Bullinger, L. and Giannopoulos, K.
International Journal of Cancer 133
(6): 1489-1496.
15 September 2013
JACUSA: site-specific identification of RNA editing events from replicate sequencing data.
Piechotta, M., Wyler, E., Ohler, U., Landthaler, M. and Dieterich, C.
BMC Bioinformatics 18
(1): 7.
3 January 2017
B-cell biology and development.
Pieper, K., Grimbacher, B. and Eibel, H.
Journal of Allergy and Clinical Immunology 131
(4): 959-971.
April 2013
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Pieper, K., Tan, J., Piccoli, L., Foglierini, M., Barbieri, S., Chen, Y., Silacci-Fregni, C., Wolf, T., Jarrossay, D., Anderle, M., Abdi, A., Ndungu, F.M., Doumbo, O.K., Traore, B., Tran, T.M., Jongo, S., Zenklusen, I., Crompton, P.D., Daubenberger, C., Bull, P.C., Sallusto, F. and Lanzavecchia, A.
Nature 548
(7669): 597-601.
31 August 2017
Mutation analysis of BRCA1 and BRCA2 genes in Iranian high risk breast cancer families.
Pietschmann, A., Mehdipour, P., Mehdipour, P., Atri, M., Hofmann, W., Hosseini-Asl, S., Scherneck, S., Mundlos, S. and Peters, H.
Journal of Cancer Research and Clinical Oncology 131
(8): 552-558.
1 January 2005
Harm or benefit of hormonal treatment in metastatic low-grade endometrial stromal sarcoma: Single center experience with 10 cases and review of the literature.
Pink, D., Lindner, T., Mrozek, A., Kretzschmar, A., Thuss-Patience, P.C., Doerken, B. and Reichardt, P.
Gynecologic Oncology 101
: 464-469.
June 2006
Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells.
Pinto, S., Sommermeyer, D., Michel, C., Wilde, S., Schendel, D., Uckert, W., Blankenstein, T. and Kyewski, B.
European Journal of Immunology 44
(9): 2811-2821.
September 2014
Targeting claudin-overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin.
Piontek, A., Eichner, M., Zwanziger, D., Beier, L.S., Protze, J., Walther, W., Theurer, S., Schmid, K.W., Führer-Sakel, D., Piontek, J. and Krause, G.
Molecular Oncology 14
(2): 261-276.
February 2020
Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes.
Pishesha, N., Harmand, T., Smeding, L.Y., Ma, W., Ludwig, L.S., Janssen, R., Islam, A., Xie, Y.J., Fang, T., McCaul, N., Pinney, W., Sugito, H.R., Rossotti, M.A., Gonzalez-Sapienza, G. and Ploegh, H.L.
Nature Biomedical Engineering 5
(11): 1389-1401.
November 2021
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M., Glažar, P., Hernandez-Miranda, L.R., Memczak, S., Wolf, S.A., Rybak-Wolf, A., Filipchyk, A., Klironomos, F., Cerda Jara, C.A., Fenske, P., Trimbuch, T., Zywitza, V., Plass, M., Schreyer, L., Ayoub, S., Kocks, C., Kühn, R., Rosenmund, C., Birchmeier, C. and Rajewsky, N.
Science 357
(6357): eaam8526.
22 September 2017
Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion.
Platzer, R., Hellmeier, J., Göhring, J., Perez, I.D., Schatzlmaier, P., Bodner, C., Focke-Tejkl, M., Schütz, G.J., Sevcsik, E., Stockinger, H., Brameshuber, M. and Huppa, J.B.
EMBO Reports 24
(11): e57842.
6 November 2023
Unscrambling fluorophore blinking for comprehensive cluster detection via photoactivated localization microscopy.
Platzer, R., Rossboth, B.K., Schneider, M.C., Sevcsik, E., Baumgart, F., Stockinger, H., Schütz, G.J., Huppa, J.B. and Brameshuber, M.
Nature Communications 11
(1): 4993.
5 October 2020
Analysis of DLC-1 expression in human breast cancer.
Plaumann, M., Seitz, S., Frege, R., Estevez-Schwarz, L. and Scherneck, S.
Journal of Cancer Research and Clinical Oncology 129
(6): 349-354.
June 2003
Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects.
Plavskin, Y., de Biase, M.S., Ziv, N., Janská, L., Zhu, Y.O., Hall, D.W., Schwarz, R.F., Tranchina, D. and Siegal, M.L.
PLoS Biology 22
(7): e3002698.
1 July 2024
The rate of spontaneous mutations in yeast deficient for MutSβ function.
Plavskin, Y., de Biase, M.S., Schwarz, R.F. and Siegal, M.L.
G3 : Genes Genomes Genetics 13
(3): jkac330.
March 2023
A differential proteome screening system for post-translational modification-dependent transcription factor interactions.
Pless, O., Kowenz-Leutz, E., Dittmar, G. and Leutz, A.
Nature Protocols 6
(3): 359-364.
February 2011
G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta.
Pless, O., Kowenz-Leutz, E., Knoblich, M., Lausen, J., Beyerman, M., Walsh, M.J. and Leutz, A.
Journal of Biological Chemistry 283
(39): 26357-26363.
26 September 2008
Generation of TGFβR2(-1) neoantigen-specific HLA-DR4-restricted T cell receptors for cancer therapy.
Plewa, N., Poncette, L. and Blankenstein, T.
Journal for ImmunoTherapy of Cancer 11
(2): e006001.
February 2023
Cox proportional hazards deep neural network identifies peripheral blood complete remission to be at least equivalent to morphologic complete remission in predicting outcomes of patients treated with azacitidine - a prospective cohort study by the AGMT.
Pleyer, L., Vaisband, M., Drost, M., Pfeilstöcker, M., Stauder, R., Heibl, S., Sill, H., Girschikofsky, M., Stampfl-Mattersberger, M., Pichler, A., Hartmann, B., Petzer, A., Schreder, M., Schmitt, C.A., Vallet, S., Melchardt, T., Zebisch, A., Pichler, P., Zaborsky, N., Machherndl-Spandl, S., Wolf, D., Keil, F., Hasenauer, J., Larcher-Senn, J. and Greil, R.
American Journal of Hematology 98
(11): 1685-1698.
November 2023
Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells.
Ploetz, M., Gillissen, B., Hossini, A.M., Daniel, P.T. and Eberle, J.
Cell Death and Differentiation 19
(12): 1928-1938.
December 2012
The BH3-only protein Bim(L) overrides Bcl-2-mediated apoptosis resistance in melanoma cells.
Ploetz, M., Gillissen, B., Quast, S.A., Berger, A., Daniel, P.T. and Eberle, J.
Cancer Letters 335
(1): 100-108.
10 July 2013
Using gradient boosting with stability selection on health insurance claims data to identify disease trajectories in chronic obstructive pulmonary disease.
Ploner, T., Heß, S., Grum, M., Drewe-Boss, P. and Walker, J.
Statistical Methods in Medical Research 29
(12): 3684-3694.
1 December 2020
The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains.
Pluska, L., Jarosch, E., Zauber, H., Kniss, A., Waltho, A., Bagola, K., von Delbrück, M., Löhr, F., Schulman, B.A., Selbach, M., Dötsch, V. and Sommer, T.
EMBO Journal 40
(6): e106094.
15 March 2021
Breast cancer: early- and late-fluorescence near-infrared imaging with indocyanine green a preliminary study.
Poellinger, A., Burock, S., Grosenick, D., Hagen, A., Luedemann, L., Diekmann, F., Engelken, F., Macdonald, R., Rinneberg, H. and Schlag, P.M.
Radiology 258
(2): 409-416.
February 2011
RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.
Poetz, F., Corbo, J., Levdansky, Y., Spiegelhalter, A., Lindner, D., Magg, V., Lebedeva, S., Schweiggert, J., Schott, J., Valkov, E. and Stoecklin, G.
Nature Communications 12
(1): 7175.
9 December 2021
Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.
Poetz, F., Lebedeva, S., Schott, J., Lindner, D., Ohler, U. and Stoecklin, G.
Genome Biology 23
(1): 193.
12 September 2022
Design of a bZip transcription factor with homo/heterodimer-induced DNA-binding preference.
Pogenberg, V., Consani Textor, L., Vanhille, L., Holton, S.J., Sieweke, M.H. and Wilmanns, M.
Structure 22
(3): 466-477.
4 March 2014
Antigen receptor-engineered Tregs inhibit CNS autoimmunity in cell therapy using non-redundant immune mechanisms in mice.
Pohar, J., O'Connor, R., Manfroi, B., Behi, M.E., Jouneau, L., Boudinot, P., Bunse, M., Uckert, W., Luka, M., Ménager, M., Liblau, R., Anderton, S.M. and Fillatreau, S.
European Journal of Immunology 52
(8): 1335-1349.
August 2022
ECG scoring for the evaluation of therapy-naïve cancer patients to predict cardiotoxicity.
Pohl, J., Mincu, R.I., Mrotzek, S.M., Wakili, R., Mahabadi, A.A., Potthoff, S.K., Siveke, J.T., Keller, U., Landmesser, U., Rassaf, T., Anker, M.S. and Totzeck, M.
Cancers 13
(6): 1197.
10 March 2021
High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients after tumor cell vaccination.
Pohla, H., Buchner, A., Stadlbauer, B., Frankenberger, B., Stevanovic, S., Walter, S., Frank, R., Schwachula, T., Olek, S., Kopp, J., Willimsky, G., Stief, C.G., Hofstetter, A., Pezzutto, A., Blankenstein, T., Oberneder, R. and Schendel, D.J.
Molecular Medicine 18
: 1499-1508.
8 February 2013
Hepatic arterial infusion in the treatment of liver metastases with PEG liposomes in combination with degradable starch microspheres (DSM) increases tumor 5-FU concentration. An animal study in CC-531 liver tumor-bearing rats.
Pohlen, U., Reszka, R., Buhr, H.J. and Berger, G.
Anticancer Research 31
(1): 147-152.
January 2011
Evolutionary plasticity in the innate immune function of Akirin.
Polanowska, J., Chen, J.X., Soulé, J., Omi, S., Belougne, J., Taffoni, C., Pujol, N., Selbach, M., Zugasti, O. and Ewbank, J.J.
PLoS Genetics 14
(7): e1007494.
23 July 2018
Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells.
Polansky, J.K., Schreiber, L., Thelemann, C., Ludwig, L., Krüger, M., Baumgrass, R., Cording, S., Floess, S., Hamann, A. and Huehn, J.
Journal of Molecular Medicine 88
(10): 1029-1040.
October 2010
Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.
Poncette, L., Chen, X., Lorenz, F.K.M. and Blankenstein, T.
Journal of Clinical Investigation 129
(1): 324-335.
2 January 2019
C/EBP beta regulation of the tumor necrosis factor alpha gene.
Pope, R.M., Leutz, A. and Ness, S.A.
Journal of Clinical Investigation 94
(4): 1449-1455.
October 1994
The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic, J., Li, L.P., Kloetzel, P.M., Leisegang, M., Uckert, W. and Blankenstein, T.
Blood 118
(4): 946-954.
28 July 2011
Bright/Arid3A acts as a barrier to somatic cell reprogramming through direct regulation of Oct4, Sox2, and Nanog.
Popowski, M., Templeton, T.D., Lee, B.K., Rhee, C., Li, H., Miner, C., Dekker, J.D., Orlanski, S., Bergman, Y., Iyer, V.R., Webb, C.F. and Tucker, H.
Stem Cell Reports 2
(1): 26-35.
14 January 2014
Impact of anti-PEG IgM antibodies on the pharmacokinetics of pegylated asparaginase preparations in mice.
Poppenborg, S.M., Wittmann, J., Walther, W., Brandenburg, G., Kraehmer, R., Baumgart, J. and Leenders, F.
European Journal of Pharmaceutical Sciences 91
: 122-130.
25 August 2016
Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads.
Porubsky, D., Ebert, P., Audano, P.A., Vollger, M.R., Harvey, W.T., Marijon, P., Ebler, J., Munson, K.M., Sorensen, M., Sulovari, A., Haukness, M., Ghareghani, M., Lansdorp, P.M., Paten, B., Devine, S.E., Sanders, A.D., Lee, C., Chaisson, M.J.P., Korbel, J.O., Eichler, E.E. and Marschall, T.
Nature Biotechnology 39
(3): 302-308.
March 2021
Dense and accurate whole-chromosome haplotyping of individual genomes.
Porubsky, D., Garg, S., Sanders, A.D., Korbel, J.O., Guryev, V., Lansdorp, P.M. and Marschall, T.
Nature Communications 8
(1): 1293.
3 November 2017
Inversion polymorphism in a complete human genome assembly.
Porubsky, D., Harvey, W.T., Rozanski, A.N., Ebler, J., Höps, W., Ashraf, H., Hasenfeld, P., Paten, B., Sanders, A.D., Marschall, T., Korbel, J.O. and Eichler, E.E.
Genome Biology 24
(1): 100.
30 April 2023
Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders.
Porubsky, D., Höps, W., Ashraf, H., Hsieh, P.H., Rodriguez-Martin, B., Yilmaz, F., Ebler, J., Hallast, P., Maggiolini, F.A.M., Harvey, W.T., Henning, B., Audano, P.A., Gordon, D.S., Ebert, P., Hasenfeld, P., Benito, E., Zhu, Q., Lee, C., Antonacci, F., Steinrücken, M., Beck, C.R., Sanders, A.D., Marschall, T., Eichler, E.E. and Korbel, J.O.
Cell 185
(11): 1986-2005.
26 May 2022
Recurrent inversion toggling and great ape genome evolution.
Porubsky, D., Sanders, A.D., Höps, W., Hsieh, P., Sulovari, A., Li, R., Mercuri, L., Sorensen, M., Murali, S.C., Gordon, D., Cantsilieris, S., Pollen, A.A., Ventura, M., Antonacci, F., Marschall, T., Korbel, J.O. and Eichler, E.E.
Nature Genetics 52
(8): 849-858.
August 2020
breakpointR: an R/Bioconductor package to localize strand state changes in Strand-seq data.
Porubsky, D., Sanders, A.D., Taudt, A., Colomé-Tatché, M., Lansdorp, P.M. and Guryev, V.
Bioinformatics 36
(4): 1260-1261.
15 February 2020
Gaps and complex structurally variant loci in phased genome assemblies.
Porubsky, D., Vollger, M.R., Harvey, W.T., Rozanski, A.N., Ebert, P., Hickey, G., Hasenfeld, P., Sanders, A.D., Stober, C., Korbel, J.O., Paten, B., Marschall, T. and Eichler, E.E.
Genome Research 33
(4): 496-510.
April 2023
Direct chromosome-length haplotyping by single-cell sequencing.
Porubský, D., Sanders, A.D., van Wietmarschen, N., Falconer, E., Hills, M., Spierings, D.C.J., Bevova, M.R., Guryev, V. and Lansdorp, P.M.
Genome Research 26
(11): 1565-1574.
November 2016
Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression.
Pospisil, H., Herrmann, A., Butherus, K., Pirson, S., Reich, J.G. and Kemmner, W.
BMC Genomics 7
: 148.
13 June 2006
Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression.
Pott, F., Postmus, D., Brown, R.J.P., Wyler, E., Neumann, E., Landthaler, M. and Goffinet, C.
Emerging Microbes & Infections 10
(1): 2151-2168.
16 November 2021
First-line treatment with R-CHOP or rituximab-bendamustine in patients with follicular lymphoma grade 3A - results of a retrospective analysis.
Pouyiourou, M., Meyer, A., Stroux, A., Viardot, A., La Rosée, P., Maschmeyer, G., Kämpfe, D., Kahl, C., Vucinic, V., Monecke, A., Hirt, C., Weber, T., Meissner, J., Witzens-Harig, M., Böttcher, S., Schmalenberg, H., Marks, R., Prange-Krex, G., Kroschinsky, F., Hauf, E., Keller, U., Koch, K., Klapper, W., Herold, M. and Scholz, C.W.
Annals of Hematology 99
(12): 2821-2829.
December 2020
Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice.
Praktiknjo, S.D., Llamas, B., Scott-Boyer, M.P., Picard, S., Robert, F., Langlais, D., Haibe-Kains, B., Faubert, D., Silversides, D.W. and Deschepper, C.F.
Endocrinology 154
(12): 4746-4756.
1 December 2013
Tracing tumorigenesis in a solid tumor model at single-cell resolution.
Praktiknjo, S.D., Obermayer, B., Zhu, Q., Fang, L., Liu, H., Quinn, H., Stoeckius, M., Kocks, C., Birchmeier, W. and Rajewsky, N.
Nature Communications 11
(1): 991.
20 February 2020
Comparisons of chromosome Y-substituted mouse strains reveal that the male-specific chromosome modulates the effects of androgens on cardiac functions.
Praktiknjo, S.D., Picard, S. and Deschepper, C.F.
Biology of Sex Differences 7
: 61.
23 November 2016
Activation of Smoothened in the Hedgehog pathway unexpectedly increases Gα(s)-dependent cAMP levels in Drosophila.
Praktiknjo, S.D., Saad, F., Maier, D., Ip, P. and Hipfner, D.R.
Journal of Biological Chemistry 293
(35): 13496-13508.
August 2018
Deletion mapping defines different regions in 1p34.2-pter that may harbor genetic information related to human colorectal cancer.
Praml, C., Finke, L.H., Herfarth, C., Schlag, P.M., Schwab, M. and Amler, L.
Oncogene 11
(7): 1357-1362.
5 October 1995
Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration.
Prechtel, A.T., Turza, N.M., Kobelt, D.J., Eisemann, J.I., Coffin, R.S., McGrath, Y., Hacker, C., Ju, X.S., Zenke, M. and Steinkasserer, A.
Journal of General Virology 86
(6): 1645-1657.
1 January 2005
Tumor-induced antibodies resemble the response to tissue damage.
Preiss, S., Kammertoens, T., Lampert, C., Willimsky, G. and Blankenstein, T.
International Journal of Cancer 115
(3): 456-462.
1 January 2005
Personalized cancer therapy considering cytochrome P450 variability.
Preissner, S., Simmaco, M., Gentile, G. and Preissner, R.
Advances in Pharmacology 74
(74): 113-130.
2015
IFNα-mediated remodeling of endothelial cells in the bone marrow niche.
Prendergast, Á.M., Kuck, A., van Essen, M., Haas, S., Blaszkiewicz, S. and Essers, M.A.G.
Haematologica 102
(3): 445-453.
March 2017
Mrpl36 is important for generation of assembly competent proteins during mitochondrial translation.
Prestele, M., Vogel, F., Reichert, A.S., Herrmann, J.M. and Ott, M.
Molecular Biology of the Cell 20
(10): 2615-2625.
May 2009
Long-term imaging reveals behavioral plasticity during C. elegans dauer exit.
Preusser, F., Neuschulz, A., Junker, J.P., Rajewsky, N. and Preibisch, S.
BMC Biology 20
(1): 277.
13 December 2022
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion.
Prinz, M., Heikenwalder, M., Junt, T., Schwarz, P., Glatzel, M., Heppner, F.L., Fu, Y.X., Lipp, M. and Aguzzi, A.
Nature 425
(6961): 957-962.
30 October 2003
COFOLD: an RNA secondary structure prediction method that takes co-transcriptional folding into account.
Proctor, J.R. and Meyer, I.M.
Nucleic Acids Research 41
(9): e102.
May 2013
Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.
Proft, S., Leiz, J., Heinemann, U., Seelow, D., Schmidt-Ott, K.M. and Rutkiewicz, M.
BMC Genomics 24
(1): 736.
4 December 2023
Induction of apoptosis by enediyne antibiotic calicheamicin gammaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner.
Prokop, A., Wrasidlo, W., Lode, H., Herold, R., Lang, F., Henze, G., Doerken, B., Wieder, T. and Daniel, P.T.
Oncogene 22
(57): 9107-9120.
11 December 2003
Automatic annotation of spatial expression patterns via sparse Bayesian factor models.
Pruteanu-Malinici, I., Mace, D.L. and Ohler, U.
PLoS Computational Biology 7
(7): e1002098.
July 2011
Active suppression induced by repetitive self-epitopes protects against EAE development.
Puentes, F., Dickhaut, K., Hofstätter, M., Falk, K. and Roetzschke, O.
PLoS ONE 8
(5): e64888.
30 May 2013
Immune modulation and prevention of autoimmune disease by repeated sequences from parasites linked to self antigens.
Puentes, F., Dickhaut, K., Hofstätter, M., Pfeil, J., Lauer, U., Hamann, A., Hoffmann, U., Falk, K. and Roetzschke, O.
Journal of Neuroimmune Pharmacology 11
(4): 749-762.
December 2016
Novel ectopic expression of zona pellucida 3 glycoprotein in lung cancer promotes tumor growth.
Pulawska-Moon, K., Ponikwicka-Tyszko, D., Lebiedzinska, W., Pilaszewicz-Puza, A., Bernaczyk, P., Koda, M., Lupu, O., Milewska, G., Huang, C.C.J., Zheng, H., Schiele, P., Na, I.K., Frentsch, M., Li, X., Toppari, J., Wolczynski, S., Coelingh Bennink, H.J.T., Huhtaniemi, I. and Rahman, N.A.
International Journal of Cancer 155
(10): 1846-1857.
15 November 2024
The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.
Pullikuth, A., McKinnon, E., Schaeffer, H.J. and Catling, A.D.
Molecular and Cellular Biology 25
(12): 5119-5133.
1 June 2005
Elimusertib has antitumor activity in preclinical patient-derived pediatric solid tumor models.
Pusch, F.F., Dorado Garcia, H., Xu, R., Gürgen, D., Bei, Y., Brückner, L., Röefzaad, C., von Stebut, J., Bardinet, V., Chamorro Gonzalez, R., Eggert, A., Schulte, J.H., Hundsdörfer, P., Seifert, G., Haase, K., Schäfer, B.W., Wachtel, M., Kühl, A.A., Ortiz, M.V., Wengner, A.M., Scheer, M. and Henssen, A.G.
Molecular Cancer Therapeutics 23
(4): 507-519.
2 April 2024
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Puttick, C., Jones, T.P., Leung, M.M., Galvez-Cancino, F., Liu, J., Varas-Godoy, M., Rowan, A., Pich, O., Martinez-Ruiz, C., Bentham, R., Dijkstra, K.K., Black, J.R.M., Rosenthal, R., Kanu, N., Litchfield, K., Salgado, R., Moore, D.A., Van Loo, P., Jamal-Hanjani, M., Quezada, S.A., Swanton, C. and McGranahan, N.
Nature Genetics 56
(10): 2121-2131.
October 2024
Better prognosis of gastric cancer patients with high levels of tumor infiltrating lymphocytes is counteracted by PD-1 expression.
Pötzsch, M., Berg, E., Hummel, M., Stein, U., von Winterfeld, M., Jöhrens, K., Rau, B., Daum, S. and Treese, C.
OncoImmunology 9
(1): 1824632.
30 September 2020
Targeting Wnt/β-catenin signaling by TET1/FOXO4 inhibits metastatic spreading and self-renewal of cancer stem cells in gastric cancer.
Qi, J., Cui, D., Wu, Q.N., Zhao, Q., Chen, Z.H., Li, L., Birchmeier, W., Yu, Y. and Tao, R.
Cancers 14
(13): 3232.
30 June 2022
New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Qi, J., Yu, Y., Akilli Öztürk, Ö., Holland, J.D., Besser, D., Fritzmann, J., Wulf-Goldenberg, A., Eckert, K., Fichtner, I. and Birchmeier, W.
Gut 65
(10): 1690-1701.
October 2016
cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries.
Qi, M., Nayar, U., Ludwig, L.S., Wagle, N. and Rheinbay, E.
BMC Bioinformatics 22
(1): 611.
24 December 2021
KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells.
Qi, X.T., Li, Y.L., Zhang, Y.Q., Xu, T., Lu, B., Fang, L., Gao, J.Q., Yu, L.S., Zhu, D.F., Yang, B., He, Q.J. and Ying, M.D.
Acta Pharmacologica Sinica 40
(4): 546-555.
April 2019
Methods for use of cytokine gene-modified tumor cells in immunotherapy of cancer.
Qin, Z. and Blankenstein, T.
Methods in Molecular Medicine 7
: 339-348.
1997
Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis.
Qin, Z., Krueger-Krasagakes, S., Kunzendorf, U., Hock, H., Diamantstein, T. and Blankenstein, T.
Journal of Experimental Medicine 178
(1): 355-360.
1 July 1993
Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte- macrophage colony-stimulating factor gene-modified tumor cells.
Qin, Z., Noffz, G., Mohaupt, M. and Blankenstein, T.
Journal of Immunology 159
(2): 770-776.
15 July 1997
A critical requirement of interferon gamma-mediated angiostasis for tumor rejection by CD8T cells.
Qin, Z.H., Schwartzkopff, J., Pradera, F., Kammertoens, T., Seliger, B., Pircher, H. and Blankenstein, T.
Cancer Research 63
(14): 4095-4100.
1 January 2003
Cryo-EM captures early ribosome assembly in action.
Qin, B., Lauer, S.M., Balke, A., Vieira-Vieira, C.H., Bürger, J., Mielke, T., Selbach, M., Scheerer, P., Spahn, C.M.T. and Nikolay, R.
Nature Communications 14
(1): 898.
17 February 2023
Inhibition of methylcholanthrene-induced carcinogenesis by an interferon gamma receptor-dependent foreign body reaction.
Qin, Z., Kim, H.J., Hemme, J. and Blankenstein, T.
Journal of Experimental Medicine 195
(11): 1479-1490.
3 June 2002
Ectopic transplastomic expression of a synthetic MatK gene leads to cotyledon-specific leaf variegation.
Qu, Y., Legen, J., Arndt, J., Henkel, S., Hoppe, G., Thieme, C., Ranzini, G., Muino, J.M., Weihe, A., Ohler, U., Weber, G., Ostersetzer, O. and Schmitz-Linneweber, C.
Frontiers in Plant Science 9
: 1453.
October 2018
Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes.
Qu, Y., Lennartsson, A., Gaidzik, V.I., Deneberg, S., Karimi, M., Bengtzén, S., Höglund, M., Bullinger, L., Döhner, K. and Lehmann, S.
Epigenetics 9
(8): 1108-1119.
August 2014
Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia.
Qu, Y., Siggens, L., Cordeddu, L., Gaidzik, V.I., Karlsson, K., Bullinger, L., Döhner, K., Ekwall, K., Lehmann, S. and Lennartsson, A.
Blood 129
(7): e13-e25.
16 February 2017
In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificity.
Quensel, C., Friedrich, B., Sommer, T., Hartmann, E. and Koehler, M.
Molecular and Cellular Biology 24
(23): 10246-10255.
1 January 2004
YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer.
Quinn, H.M., Vogel, R., Popp, O., Mertins, P., Lan, L., Messerschmidt, C., Landshammer, A., Lisek, K., Château-Joubert, S., Marangoni, E., Koren, E., Fuchs, Y. and Birchmeier, W.
Cancer Research 81
(8): 2116-2127.
April 2021
Different inhibitory potencies of oseltamivir carboxylate, zanamivir, and several tannins on bacterial and viral neuraminidases as assessed in a cell-free fluorescence-based enzyme inhibition assay.
Quosdorf, S., Schuetz, A. and Kolodziej, H.
Molecules 22
(11): 1989.
17 November 2017
Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g.
Rabl, R., Soubannier, V., Scholz, R., Vogel, F., Mendl, N., Vasiljev-Neumeyer, A., Koerner, C., Jagasia, R., Keil, T., Baumeister, W., Cyrklaff, M., Neupert, W. and Reichert, A.S.
Journal of Cell Biology 185
(6): 1047-1063.
15 June 2009
Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level.
Rach, E.A., Winter, D.R., Benjamin, A.M., Corcoran, D.L., Ni, T., Zhu, J. and Ohler, U.
PLoS Genetics 7
(1): e1001274.
13 January 2011
Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome.
Rach, E.A., Yuan, H.Y., Majoros, W.H., Tomancak, P. and Ohler, U.
Genome Biology 10
(7): R73.
9 July 2009
The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines.
Radetzki, S., Koehne, C.H., von Haefen, C., Gillissen, B., Sturm, I., Doerken, B. and Daniel, P.T.
Oncogene 21
(2): 227-238.
10 January 2002
MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.
Radhakrishnan, H., Ilm, K., Walther, W., Shirasawa, S., Sasazuki, T., Daniel, P.T., Gillissen, B. and Stein, U.
Cancer Letters 403
: 231-245.
10 September 2017
The genomic and transcriptional landscape of primary central nervous system lymphoma.
Radke, J., Ishaque, N., Koll, R., Gu, Z., Schumann, E., Sieverling, L., Uhrig, S., Hübschmann, D., Toprak, U.H., López, C., Hostench, X.P., Borgoni, S., Juraeva, D., Pritsch, F., Paramasivam, N., Balasubramanian, G.P., Schlesner, M., Sahay, S., Weniger, M., Pehl, D., Radbruch, H., Osterloh, A., Korfel, A., Misch, M., Onken, J., Faust, K., Vajkoczy, P., Moskopp, D., Wang, Y., Jödicke, A., Trümper, L., Anagnostopoulos, I., Lenze, D., Küppers, R., Hummel, M., Schmitt, C.A., Wiestler, O.D., Wolf, S., Unterberg, A., Eils, R., Herold-Mende, C., Brors, B., Siebert, R., Wiemann, S. and Heppner, F.L.
Nature Communications 13
(1): 2558.
10 May 2022
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Radke, J., Meinhardt, J., Aschman, T., Chua, R.L., Farztdinov, V., Lukassen, S., Ten, F.W., Friebel, E., Ishaque, N., Franz, J., Huhle, V.H., Mothes, R., Peters, K., Thomas, C., Schneeberger, S., Schumann, E., Kawelke, L., Jünger, J., Horst, V., Streit, S., von Manitius, R., Körtvélyessy, P., Vielhaber, S., Reinhold, D., Hauser, A.E., Osterloh, A., Enghard, P., Ihlow, J., Elezkurtaj, S., Horst, D., Kurth, F., Müller, M.A., Gassen, N.C., Melchert, J., Jechow, K., Timmermann, B., Fernandez-Zapata, C., Böttcher, C., Stenzel, W., Krüger, E., Landthaler, M., Wyler, E., Corman, V., Stadelmann, C., Ralser, M., Eils, R., Heppner, F.L., Mülleder, M., Conrad, C. and Radbruch, H.
Nature Neuroscience 27
(3): 409-420.
March 2024
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.
Raffel, S., Falcone, M., Kneisel, N., Hansson, J., Wang, W., Lutz, C., Bullinger, L., Poschet, G., Nonnenmacher, Y., Barnert, A., Bahr, C., Zeisberger, P., Przybylla, A., Sohn, M., Tönjes, M., Erez, A., Adler, L., Jensen, P., Scholl, C., Fröhling, S., Cocciardi, S., Wuchter, P., Thiede, C., Flörcken, A., Westermann, J., Ehninger, G., Lichter, P., Hiller, K., Hell, R., Herrmann, C., Ho, A.D., Krijgsveld, J., Radlwimmer, B. and Trumpp, A.
Nature 551
(7680): 384-388.
16 November 2017
Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells.
Raffel, S., Klimmeck, D., Falcone, M., Demir, A., Pouya, A., Zeisberger, P., Lutz, C., Tinelli, M., Bischel, O., Bullinger, L., Thiede, C., Flörcken, A., Westermann, J., Ehninger, G., Ho, A.D., Müller-Tidow, C., Gu, Z., Herrmann, C., Krijgsveld, J., Trumpp, A. and Hansson, J.
Blood 136
(13): 1507-1519.
24 September 2020
Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma.
Rahal, R., Frick, M., Romero, R., Korn, J.M., Kridel, R., Chun Chan, F., Meissner, B., Bhang, H.E., Ruddy, D., Kauffmann, A., Farsidjani, A., Derti, A., Rakiec, D., Naylor, T., Pfister, E., Kovats, S., Kim, S., Dietze, K., Doerken, B., Steidl, C., Tzankov, A., Hummel, M., Monahan, J., Morrissey, M.P., Fritsch, C., Sellers, W.R., Cooke, V.G., Gascoyne, R.D., Lenz, G. and Stegmeier, F.
Nature Medicine 20
(1): 87-92.
January 2014
MAD2L2 promotes open chromatin in embryonic stem cells and derepresses the Dppa3 locus.
Rahjouei, A., Pirouz, M., Di Virgilio, M., Kamin, D. and Kessel, M.
Stem Cell Reports 8
(4): 813-821.
11 April 2017
Kinase-controlled phase transition of membraneless organelles in mitosis.
Rai, A.K., Chen, J.X., Selbach, M. and Pelkmans, L.
Nature 559
(7713): 211-216.
July 2018
Treatment of young patients with HNF1A mutations (HNF1A-MODY).
Raile, K., Schober, E., Konrad, K., Thon, A., Grulich-Henn, J., Meissner, T., Woelfle, J., Scheuing, N. and Holl, R.W.
Diabetic Medicine 32
(4): 526-530.
April 2015
Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses.
Rajasekaran, S., Siddiqui, J., Rakijas, J., Nicolay, B., Lin, C., Khan, E., Patel, R., Morris, R., Wyler, E., Boukhali, M., Balasubramanyam, J., Ranjith Kumar, R., Van Rechem, C., Vogel, C., Elchuri, S.V., Landthaler, M., Obermayer, B., Haas, W., Dyson, N. and Miles, W.
Communications Biology 4
(1): 977.
17 August 2021
The Herzenberg lecture: how to make a B-1 cell?
Rajewsky, K.
Annals of the New York Academy of Sciences 1362
(1): 6-7.
December 2015
Increased salt consumption induces body water conservation and decreases fluid intake.
Rakova, N., Kitada, K., Lerchl, K., Dahlmann, A., Birukov, A., Daub, S., Kopp, C., Pedchenko, T., Zhang, Y., Beck, L., Johannes, B., Marton, A., Müller, D.N., Rauh, M., Luft, F.C. and Titze, J.
Journal of Clinical Investigation 127
(5): 1932-1943.
1 May 2017
Metadata-guided feature disentanglement for functional genomics.
Rakowski, A., Monti, R., Huryn, V., Lemanczyk, M., Ohler, U. and Lippert, C.
Bioinformatics 40
(Suppl 2): ii4-ii10.
September 2024
TransferGWAS of T1-weighted brain MRI data from UK Biobank.
Rakowski, A., Monti, R. and Lippert, C.
PLoS Genetics 20
(12): e1011332.
13 December 2024
(In Press)
miR-9-5p in nephrectomy specimens is a potential predictor of primary resistance to first-line treatment with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma.
Ralla, B., Busch, J., Flörcken, A., Westermann, J., Zhao, Z., Kilic, E., Weickmann, S., Jung, M., Fendler, A. and Jung, K.
Cancers 10
(9): 321.
10 September 2018
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.
Ramberger, E., Sapozhnikova, V., Kowenz-Leutz, E., Zimmermann, K., Nicot, N., Nazarov, P.V., Perez-Hernandez, D., Reimer, U., Mertins, P., Dittmar, G. and Leutz, A.
iScience 24
(6): 102686.
25 June 2021
The proteogenomic landscape of multiple myeloma reveals insights into disease biology and therapeutic opportunities.
Ramberger, E., Sapozhnikova, V., Ng, Y.L.D., Dolnik, A., Ziehm, M., Popp, O., Sträng, E., Kull, M., Grünschläger, F., Krüger, J., Benary, M., Müller, S., Gao, X., Murgai, A., Haji, M., Schmidt, A., Lutz, R., Nogai, A., Braune, J., Laue, D., Langer, C., Khandanpour, C., Bassermann, F., Döhner, H., Engelhardt, M., Straka, C., Hundemer, M., Beule, D., Haas, S., Keller, U., Einsele, H., Bullinger, L., Knop, S., Mertins, P. and Krönke, J.
Nature Cancer 5
(8): 1267-1284.
August 2024
A universal peptide matrix interactomics approach to disclose motif dependent protein binding.
Ramberger, E., Suarez-Artiles, L., Perez-Hernandez, D., Haji, M., Popp, O., Reimer, U., Leutz, A., Dittmar, G. and Mertins, P.
Molecular & Cellular Proteomics 20
: 100135.
13 August 2021
A structural role for ATP in the formation and stability of the human origin recognition complex.
Ranjan, A. and Gossen, M.
Proceedings of the National Academy of Sciences of the United States of America 103
(13): 4864-4869.
28 March 2006
Involvement of the Gal β1 - 3GalNAcβ structure in the recognition of apoptotic bodies by THP-1 cells.
Rapoport, E., Khaidukov, S., Baidina, O., Bojenko, V., Moiseeva, E., Pasynina, G., Karsten, U., Nifantev, N., LePendu, J. and Bovin, N.
European Journal of Cell Biology 82
(6): 295-302.
June 2003
FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer.
Raschzok, N., Stintzing, S., Heinemann, V., Rauch, G., Ricke, J., Guckenberger, M., Kurreck, A., Alig, A.H.S., Stahler, A., Bullinger, L., Schmelzle, M., Schöning, W., Lurje, G., Krenzien, F., Haase, O., Rau, B., Gebauer, B., Sauer, I.M., Pratschke, J. and Modest, D.P.
BMC Cancer 22
(1): 359.
2 April 2022
Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression.
Rasheed, A.U., Rahn, H.P., Sallusto, F., Lipp, M. and Mueller, G.
European Journal of Immunology 36
(7): 1892-1903.
July 2006
A novel gene controls a new structure: piggyBac transposable element-derived 1, unique to mammals, controls mammal-specific neuronal paraspeckles.
Raskó, T., Pande, A., Radscheit, K., Zink, A., Singh, M., Sommer, C., Wachtl, G., Kolacsek, O., Inak, G., Szvetnik, A., Petrakis, S., Bunse, M., Bansal, V., Selbach, M., Orbán, T.I., Prigione, A., Hurst, L.D. and Izsvák, Z.
Molecular Biology and Evolution 39
(10): msac175.
October 2022
Common clonal origin of an acute B lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity.
Ratei, R., Hummel, M., Anagnostopoulos, I., Jaehne, D., Arnold, R., Doerken, B., Mathas, S., Thomas, B., Dudeck, O., Ludwig, W.D. and Stein, H.
Haematologica 95
(9): 1461-1466.
September 2010
Salvage therapy for relapsed mediastinal B-cell lymphoma with allogeneic HLA-identical related donor bone marrow transplantation, donor lymphocyte infusion and IDEC-C2B8.
Ratei, R., Matylis, A., Krahl, D., Arnold, R., Stein, H., Doerken, B. and Ludwig, W.D.
Leukemia & Lymphoma 40
(1-2): 133-140.
December 2000
The use of microarray technologies in mantle cell lymphoma.
Ratsch, B.A., Grau, M., Doerken, B., Lenz, P. and Lenz, G.
Seminars in Hematology 48
(3): 166-171.
July 2011
A design strategy to generate a SARS-CoV-2 RBD vaccine that abrogates ACE2 binding and improves neutralizing antibody responses.
Ratswohl, C., Vázquez García, C., Ahmad, A.U.W., Gonschior, H., Lebedin, M., Silvis, C.E., Spatt, L., Gerhard, C., Lehmann, M., Sander, L.E., Kurth, F., Olsson, S. and de la Rosa, K.
European Journal of Immunology 53
(10): e2350408.
October 2023
Preoperative radiochemotherapy in locally advanced or recurrent rectal cancer: regional radiofrequency hyperthermia correlates with clinical parameters.
Rau, B., Wust, P., Tilly, W., Gellermann, J., Harder, C., Riess, H., Budach, V., Felix, R. and Schlag, P.M.
International Journal of Radiation Oncology, Biology, Physics 48
(2): 381-391.
6 September 2000
Zur Bedeutung von beta-hCG im Serum als Tumormarker fuer das Magenkarzinom.
Rau, B., Below, C., Haensch, W., Liebrich, W., von Schilling, C. and Schlag, P.M.
Langenbecks Archiv fuer Chirurgie 380
(6): 359-364.
1 January 1995
Dynamic expression profile of p21 WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy.
Rau, B., Sturm, I., Lage, H., Berger, S., Schneider, U., Haupfmann, S., Wust, P., Riess, H., Schlag, P.M., Doerken, B. and Daniel, P.T.
Journal of Clinical Oncology 21
(18): 3391-3401.
15 September 2003
Treatment of infants and children with SARS-CoV-2 monoclonal antibodies: a European case series.
Rau, C., Auer-Hackenberg, L., Deubzer, H.E., Schwabel, E., Jaros, M., Diederichs, A., Lehrnbecher, T., Holm, M., von Linstow, M.L., Martin, L., Dinges, S.S., Rothensteiner, M., Siepermann, M., Strenger, V., von Both, U., Teig, N., Brinkmann, F., Leeb, F., Zeitlinger, M., Kobbe, R. and Götzinger, F.
Pediatric Infectious Disease Journal 42
(2): 125-129.
February 2023
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch, A., Seitz, S., Baschant, U., Schilling, A.F., Illing, A., Stride, B., Kirilov, M., Mandic, V., Takacz, A., Schmidt-Ullrich, R., Ostermay, S., Schinke, T., Spanbroek, R., Zaiss, M.M., Angel, P.E., Lerner, U.H., David, J.P., Reichardt, H.M., Amling, M., Schuetz, G. and Tuckermann, J.P.
Cell Metabolism 11
(6): 517-531.
9 June 2010
Long-read sequencing of diagnosis and post-therapy medulloblastoma reveals complex rearrangement patterns and epigenetic signatures.
Rausch, T., Snajder, R., Leger, A., Simovic, M., Giurgiu, M., Villacorta, L., Henssen, A.G., Fröhling, S., Stegle, O., Birney, E., Bonder, M.J., Ernst, A. and Korbel, J.O.
Cell Genomics 3
(4): 100281.
12 April 2023
Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity.
Rauschmeier, R., Gustafsson, C., Reinhardt, A., A-Gonzalez, N., Tortola, L., Cansever, D., Subramanian, S., Taneja, R., Rossner, M.J., Sieweke, M.H., Greter, M., Månsson, R., Busslinger, M. and Kreslavsky, T.
EMBO Journal 38
(19): e101233.
1 October 2019
Liam tackles complex multimodal single-cell data integration challenges.
Rautenstrauch, P. and Ohler, U.
Nucleic Acids Research 52
(12): e52.
8 July 2024
Expanding the phenotype of NUP85 mutations beyond nephrotic syndrome to primary autosomal recessive microcephaly and Seckel syndrome spectrum disorders.
Ravindran, E., Jühlen, R., Vieira-Vieira, C.H., Ha, T., Salzberg, Y., Fichtman, B., Luise-Becker, L., Martins, N., Picker-Minh, S., Bessa, P., Arts, P., Jackson, M.R., Taranath, A., Kamien, B., Barnett, C., Li, N., Tarabykin, V., Stoltenburg-Didinger, G., Harel, A., Selbach, M., Dickmanns, A., Fahrenkrog, B., Hu, H., Scott, H. and Kaindl, A.M.
Human Molecular Genetics 30
(22): 2068-2081.
15 November 2021
Multivalent scFv display of phagemid repertoires for the selection of carbohydrate-specific antibodies and its application to the Thomsen-Friedenreich antigen.
Ravn, P., Danielczyk, A., Jensen, K.B., Kristensen, P., Christensen, P.A., Larsen, M., Karsten, U. and Goletz, S.
Journal of Molecular Biology 343
(4): 985-996.
29 October 2004
The Thomsen-Friedenreich disaccharide as antigen for in vivo tumor targeting with multivalent scFvs.
Ravn, P., Stahn, R., Danielczyk, A., Faulstich, D., Karsten, U. and Goletz, S.
Cancer Immunology Immunotherapy 56
(9): 1345-1357.
September 2007
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features.
Ray, J.P., de Boer, C.G., Fulco, C.P., Lareau, C.A., Kanai, M., Ulirsch, J.C., Tewhey, R., Ludwig, L.S., Reilly, S.K., Bergman, D.T., Engreitz, J.M., Issner, R., Finucane, H.K., Lander, E.S., Regev, A. and Hacohen, N.
Nature Communications 11
(1): 1237.
6 March 2020
The mole genome reveals regulatory rearrangements associated with adaptive intersexuality.
Real, F.M., Haas, S.A., Franchini, P., Xiong, P., Simakov, O., Kuhl, H., Schöpflin, R., Heller, D., Moeinzadeh, M.H., Heinrich, V., Krannich, T., Bressin, A., Hartmann, M.F., Wudy, S.A., Dechmann, D.K.N., Hurtado, A., Barrionuevo, F.J., Schindler, M., Harabula, I., Osterwalder, M., Hiller, M., Wittler, L., Visel, A., Timmermann, B., Meyer, A., Vingron, M., Jiménez, R., Mundlos, S. and Lupiáñez, D.G.
Science 370
(6513): 208-214.
9 October 2020
Cell adhesion and immune response, two main functions altered in the transcriptome of seasonally regressed testes of two mammalian species.
Real, F.M., Lao-Pérez, M., Burgos, M., Mundlos, S., Lupiáñez, D.G., Jiménez, R. and Barrionuevo, F.J.
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 340
(3): 231-244.
May 2023
A microRNA (mmu-miR-124) prevents Sox9 expression in developing mouse ovarian cells.
Real, F.M., Sekido, R., Lupiáñez, D.G., Lovell-Badge, R., Jiménez, R. and Burgos, M.
Biology of Reproduction 89
(4): 78.
1 October 2013
Lineage-resolved enhancer and promoter usage during a time course of embryogenesis.
Reddington, J.P., Garfield, D.A., Sigalova, O.M., Karabacak Calviello, A., Marco-Ferreres, R., Girardot, C., Viales, R.R., Degner, J.F., Ohler, U. and Furlong, E.E.M.
Developmental Cell 55
(5): 648-664.
7 December 2020
E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
Redmer, T., Diecke, S., Grigoryan, T., Quiroga-Negreira, A., Birchmeier, W. and Besser, D.
EMBO Reports 12
(7): 720-726.
1 July 2011
The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells.
Redmer, T., Welte, Y., Behrens, D., Fichtner, I., Przybilla, D., Wruck, W., Yaspo, M.L., Lehrach, H., Schaefer, R. and Regenbrecht, C.R.A.
PLoS ONE 9
(5): e92596.
5 May 2014
JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.
Redmer, T., Raigel, M., Sternberg, C., Ziegler, R., Probst, C., Lindner, D., Aufinger, A., Limberger, T., Trachtova, K., Kodajova, P., Högler, S., Schlederer, M., Stoiber, S., Oberhuber, M., Bolis, M., Neubauer, H.A., Miranda, S., Tomberger, M., Harbusch, N.S., Garces de Los Fayos Alonso, I., Sternberg, F., Moriggl, R., Theurillat, J.P., Tichy, B., Bystry, V., Persson, J.L., Mathas, S., Aberger, F., Strobl, B., Pospisilova, S., Merkel, O., Egger, G., Lagger, S. and Kenner, L.
Molecular Cancer 23
(1): 114.
29 May 2024
Genome annotation assessment in Drosophila melanogaster.
Reese, M.G., Hartzell, G., Harris, N.L., Ohler, U., Abril, J.F. and Lewis, S.E.
Genome Research 10
(4): 483-501.
April 2000
C/EBPβ regulates homeostatic and oncogenic gastric cell proliferation.
Regalo, G., Förster, S., Resende, C., Bauer, B., Fleige, B., Kemmner, W., Schlag, P.M., Meyer, T.F., Machado, J.C. and Leutz, A.
Journal of Molecular Medicine 94
(12): 1385-1395.
December 2016
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma.
Regina, C., Hamed, E., Andrieux, G., Angenendt, S., Schneider, M., Ku, M., Follo, M., Wachtel, M., Ke, E., Kikuchi, K., Henssen, A.G., Schäfer, B.W., Boerries, M., Wagers, A.J., Keller, C. and Hettmer, S.
Life Science Alliance 4
(9): e202001002.
September 2021
Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma.
Rehm, A., Anagnostopoulos, I., Gerlach, K., Broemer, M., Scheidereit, C., Joehrens, K., Huebler, M., Hetzer, R., Stein, H., Lipp, M., Doerken, B. and Höpken, U.E.
International Journal of Cancer 125
(10): 2367-2374.
15 November 2009
Human cytomegalovirus gene products US2 and US11 differ in their ability to attack major histocompatibility class I heavy chains in dendritic cells.
Rehm, A., Engelsberg, A., Tortorella, D., Körner, I.J., Lehmann, I., Ploegh, H.L. and Höpken, U.E.
Journal of Virology 76
(10): 5043-5050.
May 2002
Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A., Gätjen, M., Gerlach, K., Scholz, F., Mensen, A., Gloger, M., Heinig, K., Lamprecht, B., Mathas, S., Bégay, V., Leutz, A., Lipp, M., Dörken, B. and Höpken, U.E.
Nature Communications 5
: 5057.
30 September 2014
Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Rehm, A., Mensen, A., Schradi, K., Gerlach, K., Wittstock, S., Winter, S., Buechner, G., Doerken, B., Lipp, M. and Höpken, U.E.
Blood 118
(4): 1020-1033.
28 July 2011
EBAG9 controls CD8(+) T cell memory formation responding to tumor challenge in mice.
Rehm, A., Wirges, A., Hoser, D., Fischer, C., Herda, S., Gerlach, K., Sauer, S., Willimsky, G. and Hoepken, U.E.
JCI Insight 7
(11): e155534.
8 June 2022
Empirical antimicrobial monotherapy in patients after high-dose chemotherapy and autologous stem cell transplantation: a randomised, multicentre trial.
Reich, G., Cornely, O.A., Sandherr, M., Kubin, T., Krause, S., Einsele, H., Thiel, E., Bellaire, T., Doerken, B. and Maschmeyer, G.
British Journal of Haematology 130
: 265-270.
1 July 2005
An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma.
Reichardt, P., Oechsle, K., Pink, D., Bokemeyer, C., Schneller, F., Issels, R., Kanz, L. and Hartmann, J.T.
Investigational New Drugs 21
: 481-486.
1 November 2003
Dose-intensive chemotherapy with ifosfamide, epirubicin, and filgrastim for adult patients with metastatic or locally advanced soft tissue sarcoma: A phase II study.
Reichardt, P., Tilgner, J., Hohenberger, P. and Doerken, B.
Journal of Clinical Oncology 16
(4): 1438-1443.
April 1998
Identification and quantification of in vitro adduct formation between protein reactive xenobiotics and a lysine-containing model peptide.
Reichardt, P., Schreiber, A., Wichmann, G., Metzner, G., Efer, J. and Raabe, F.
Environmental Toxicology 18
: 29-36.
1 February 2003
Comparison of FACS and PCR for detection of BCMA-CAR-T cells.
Reichman, A., Kunz, A., Joedicke, J.J., Höpken, U.E., Keib, A., Neuber, B., Sedloev, D., Wang, L., Jiang, G., Hückelhoven-Krauss, A., Eberhardt, F., Müller-Tidow, C., Wermke, M., Rehm, A., Schmitt, M. and Schmitt, A.
International Journal of Molecular Sciences 23
(2): 903.
14 January 2022
The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Reimann, M., Loddenkemper, C., Rudolph, C., Schildhauer, I., Teichmann, B., Stein, H., Schlegelberger, B., Doerken, B. and Schmitt, C.A.
Blood 110
(8): 2996-3004.
15 October 2007
Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Reimann, M., Lee, S., Loddenkemper, C., Dörr, J.R., Tabor, V., Aichele, P., Stein, H., Doerken, B., Jenuwein, T. and Schmitt, C.A.
Cancer Cell 17
(3): 262-272.
16 March 2010
Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Reimann, M., Schrezenmeier, J.F., Richter-Pechanska, P., Dolnik, A., Hick, T.P., Schleich, K., Cai, X., Fan, D.N.Y., Lohneis, P., Masswig, S., Denker, S., Busse, A., Knittel, G., Flümann, R., Childs, D., Childs, L., Gätjens-Sanchez, A.M., Bullinger, L., Rosenwald, A., Reinhardt, H.C. and Schmitt, C.A.
Blood 137
(20): 2785-2899.
20 May 2021
Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker.
Reimer, T.A., Anagnostopoulos, I., Erdmann, B., Lehmann, I., Stein, H., Daniel, P., Doerken, B. and Rehm, A.
BMC Cancer 5
(1): 47.
1 January 2005
Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72.
Reinbold, M., Luo, J.L., Nedelko, T., Jerchow, B., Murphy, M.E., Whibley, C., Wei, Q. and Hollstein, M.
Oncogene 27
(19): 2788-2794.
24 April 2008
Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1.
Reinke, S., Bröckelmann, P.J., Iaccarino, I., Garcia-Marquez, M., Borchmann, S., Jochims, F., Kotrova, M., Pal, K., Brüggemann, M., Hartmann, E., Sasse, S., Kobe, C., Mathas, S., Soekler, M., Keller, U., Bormann, M., Zimmermann, A., Richter, J., Fuchs, M., von Tresckow, B., Borchmann, P., Schlößer, H., von Bergwelt-Baildon, M., Rosenwald, A., Engert, A. and Klapper, W.
Blood 136
(25): 2851-2863.
17 December 2020
Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86.
Reiter, A., Schrappe, M., Ludwig, W.D., Hiddemann, W., Sauter, S., Henze, G., Zimmermann, M., Lampert, F., Havers, W., Niethammer, D., Odenwald, E., Ritter, J., Mann, G., Welte, K., Gadner, H. and Riehm, H.
Blood 84
(9): 3122-3133.
1 November 1994
Postnatal DNA demethylation and its role in tissue maturation.
Reizel, Y., Sabag, O., Skversky, Y., Spiro, A., Steinberg, B., Bernstein, D., Wang, A., Kieckhaefer, J., Li, C., Pikarsky, E., Levin-Klein, R., Goren, A., Rajewsky, K., Kaestner, K.H. and Cedar, H.
Nature Communications 9
(1): 2040.
23 May 2018
Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion.
Rejeski, K., Perez, A., Iacoboni, G., Blumenberg, V., Bücklein, V.L., Völkl, S., Penack, O., Albanyan, O., Stock, S., Müller, F., Karschnia, P., Petrera, A., Reid, K., Faramand, R., Davila, M.L., Modi, K., Dean, E.A., Bachmeier, C., von Bergwelt-Baildon, M., Locke, F.L., Bethge, W., Bullinger, L., Mackensen, A., Barba, P., Jain, M.D. and Subklewe, M.
Science Advances 9
(38): eadg3919.
22 September 2023
The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL.
Rejeski, K., Perez, A., Iacoboni, G., Penack, O., Bücklein, V., Jentzsch, L., Mougiakakos, D., Johnson, G., Arciola, B., Carpio, C., Blumenberg, V., Hoster, E., Bullinger, L., Locke, F.L., von Bergwelt-Baildon, M., Mackensen, A., Bethge, W., Barba, P., Jain, M.D. and Subklewe, M.
Journal for ImmunoTherapy of Cancer 10
(5): e004475.
17 May 2022
New insights into the cellular temporal response to proteostatic stress.
Rendleman, J., Cheng, Z., Maity, S., Kastelic, N., Munschauer, M., Allgoewer, K., Teo, G., Zhang, Y.B.M., Lei, A., Parker, B., Landthaler, M., Freeberg, L., Kuersten, S., Choi, H. and Vogel, C.
eLife 7
: e39054.
12 October 2018
Abnormal biomarkers predict complex FAS or FADD defects missed by exome sequencing.
Rensing-Ehl, A., Lorenz, M.R., Führer, M., Willenbacher, W., Willenbacher, E., Sopper, S., Abinun, M., Maccari, M.E., König, C., Haegele, P., Fuchs, S., Castro, C., Kury, P., Pelle, O., Klemann, C., Heeg, M., Thalhammer, J., Wegehaupt, O., Fischer, M., Goldacker, S., Schulte, B., Biskup, S., Chatelain, P., Schuster, V., Warnatz, K., Grimbacher, B., Meinhardt, A., Holzinger, D., Oommen, P.T., Hinze, T., Hebart, H., Seeger, K., Lehmberg, K., Leahy, T.R., Claviez, A., Vieth, S., Schilling, F.H., Fuchs, I., Groß, M., Rieux-Laucat, F., Magerus, A., Speckmann, C., Schwarz, K. and Ehl, S.
Journal of Allergy and Clinical Immunology 153
(1): 297-308.
January 2024
Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation.
Rettig, I., Koeneke, E., Trippel, F., Mueller, W.C., Burhenne, J., Kopp-Schneider, A., Fabian, J., Schober, A., Fernekorn, U., von Deimling, A., Deubzer, H.E., Milde, T., Witt, O. and Oehme, I.
Cell Death & Disease 6
: e1657.
19 February 2015
Crystal structure of the dynamin tetramer.
Reubold, T.F., Faelber, K., Plattner, N., Posor, Y., Ketel, K., Curth, U., Schlegel, J., Anand, R., Manstein, D.J., Noé, F., Haucke, V., Daumke, O. and Eschenburg, S.
Nature 525
(7569): 404-408.
17 September 2015
Suspension packaging cell lines for the simplified generation of T-cell receptor encoding retrovirus vector particles.
Reuß, S., Biese, P., Cosset, F.L., Takeuchi, Y. and Uckert, W.
Gene Therapy 14
(7): 595-603.
April 2007
TCR-engineered T cells: a model of inducible TCR expression to dissect the interrelationship between two TCRs.
Reuß, S., Sebestyén, Z., Heinz, N., Loew, R., Baum, C., Debets, R. and Uckert, W.
European Journal of Immunology 44
(1): 265-274.
January 2014
EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation.
Reynolds, A.R., Tischer, C., Verveer, P.J., Rocks, O. and Bastiaens, P.I.
Nature Cell Biology 5
(5): 447-453.
May 2003
CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia.
Rhein, P., Mitlohner, R., Basso, G., Gaipa, G., Dworzak, M.N., Kirschner-Schwabe, R., Hagemeier, C., Stanulla, M., Schrappe, M., Ludwig, W.D., Karawajew, L. and Ratei, R.
Blood 115
(18): 3763-3771.
6 May 2010
TCR gene therapy for cancer.
Rhein, S. and Çakmak-Görür, N.
Methods in Molecular Biology 2521
(3): 95-128.
23 June 2022
Expression of the Thomsen-Friedenreich (TF) tumor antigen in human abort placentas.
Richter, D.U., Jeschke, U., Bergemann, C., Makovitzky, J., Luthen, F., Karsten, U. and Briese, V.
Anticancer Research 25
(3 A): 1675-1678.
1 January 2005
Interleukin 10 transfected into Chinese hamster ovary cells prevents tumor growth and macrophage infiltration.
Richter, G., Krueger-Krasagakes, S., Hein, G., Huels, C., Schmitt, E., Diamantstein, T. and Blankenstein, T.
Cancer Research 53
(18): 4134-4137.
15 September 1993
In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors.
Richter, M., Saydaminova, K., Yumul, R., Krishnan, R., Liu, J., Nagy, E.E., Singh, M., Izsvák, Z., Cattaneo, R., Uckert, W., Palmer, D., Ng, P., Haworth, K.G., Kiem, H.P., Ehrhardt, A., Papayannopoulou, T. and Lieber, A.
Blood 128
(18): 2206-2217.
3 November 2016
90-yttrium-ibritumomab tiuxetan as first-line treatment for follicular lymphoma: updated efficacy and safety results at an extended median follow-up of 9.6 years.
Rieger, K., De Filippi, R., Lindén, O., Viardot, A., Hess, G., Lerch, K., Neumeister, P., Stroux, A., Peuker, C.A., Pezzutto, A., Pinto, A., Keller, U. and Scholz, C.W.
Annals of Hematology 101
(4): 781-788.
April 2022
Confocal endomicroscopy in diagnosis of intestinal chronic graft-versus-host disease.
Rieger, K., Günther, U., Erben, U., Kühl, A., Loddenkemper, C., Pezzutto, A., Siegmund, B. and Bojarski, C.
Hematological Oncology 36
(1): 291-298.
February 2018
Renal extramedullary hematopoiesis in mast cell leukemia with bone marrow fibrosis.
Rieke, D.T., Schmalbrock, L.K., Ihlow, J., Kleo, K., von Brünneck, A.C., Nolte, F., Keller, U. and Ochsenreither, S.
Case Reports in Hematology 2024
: 1-6.
3 January 2024
Targeted treatment in a case series of AR+, HRAS/PIK3CA co-mutated salivary duct carcinoma.
Rieke, D.T., Schröder, S., Schafhausen, P., Blanc, E., Zuljan, E., von der Emde, B., Beule, D., Keller, U., Keilholz, U. and Klinghammer, K.
Frontiers in Oncology 13
: 1107134.
2023
Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells.
Riemann, M., Andreas, N., Fedoseeva, M., Meier, E., Weih, D., Freytag, H., Schmidt-Ullrich, R., Klein, U., Wang, Z.Q. and Weih, F.
Journal of Autoimmunity 81
: 56-67.
July 2017
Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.
Riemke, P., Czeh, M., Fischer, J., Walter, C., Ghani, S., Zepper, M., Agelopoulos, K., Lettermann, S., Gebhardt, M.L., Mah, N., Weilemann, A., Grau, M., Groening, V., Haferlach, T., Lenze, D., Delwel, R., Prinz, M., Andrade-Navarro, M.A., Lenz, G., Dugas, M., Mueller-Tidow, C. and Rosenbauer, F.
EMBO Journal 35
(22): 2399-2416.
15 November 2016
Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K., Shi, Y., Jacobi, A., Kräter, M., Kalupa, M., McGearey, A., Mertlitz, S., Cordes, S., Schrezenmeier, J.F., Mengwasser, J., Westphal, S., Perez-Hernandez, D., Schmitt, C., Dittmar, G., Guck, J. and Penack, O.
Blood 129
(14): 2021-2032.
6 April 2017
Rationale and design of PROSPECT-CONKO 004: a prospective, randomized trial of simultaneous pancreatic cancer treatment with enoxaparin and chemotherapy.
Riess, H., Pelzer, U., Hilbig, A., Stieler, J., Opitz, B., Scholten, T., Kauschat-Bruning, D., Bramlage, P., Doerken, B. and Oettle, H.
BMC Cancer 8
(1): 361.
5 December 2008
Biochemical and functional characterization of the murine ros protooncogene.
Riethmacher, D., Langholz, O., Goedecke, S., Sachs, M. and Birchmeier, C.
Oncogene 9
(12): 3617-3626.
December 1994
A high content screening assay for evaluation of biomaterial-mediated cell fusion processes.
Rijckaert, B., Neffe, A.T., Roch, T., Gebauer, T., Pierce, B.F., Görs, J., Smink, J.J., Gossen, M., Lendlein, A. and Leutz, A.
Macromolecular Symposia 346
(1): 91-99.
December 2014
Effects of Jak2 type 1 inhibitors NVP-BSK805 and NVP-BVB808 on Jak2 mutation-positive and Bcr-Abl-positive cell lines.
Ringel, F., Kaeda, J., Schwarz, M., Oberender, C., Grille, P., Doerken, B., Marque, F., Manley, P.W., Radimerski, T. and le Coutre, P.
Acta Haematologica 132
(1): 75-86.
31 January 2014
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes.
Ringel, A.R., Szabo, Q., Chiariello, A.M., Chudzik, K., Schöpflin, R., Rothe, P., Mattei, A.L., Zehnder, To., Harnett, D., Laupert, V., Bianco, S., Hetzel, S., Glaser, J., Phan, M.H.Q., Schindler, M., Ibrahim, D.M., Paliou, C., Esposito, A., Prada-Medina, C.A., Haas, S.A., Giere, P., Vingron, M., Wittler, L., Meissner, A., Nicodemi, M., Cavalli, G., Bantignies, F., Mundlos, S. and Robson, M.I.
Cell 185
(20): 3689-3704.
29 September 2022
Scanning time-domain optical mammography: detection and characterization of breast tumors in vivo.
Rinneberg, H., Grosenick, D., Moesta, K.T., Mucke, J., Gebauer, B., Stroszczynski, C., Wabnitz, H., Moeller, M., Wassermann, B. and Schlag, P.M.
Technology in Cancer Research & Treatment 4
(5): 483-496.
1 October 2005
Capecitabine in combination with bendamustine in pretreated women with HER2-negative metastatic breast cancer: results of a phase II trial (AGMT MBC-6).
Rinnerthaler, G., Gampenrieder, S.P., Petzer, A., Hubalek, M., Petru, E., Sandholzer, M., Andel, J., Balic, M., Melchardt, T., Hauser-Kronberger, C., Schmitt, C.A., Ulmer, H. and Greil, R.
Therapeutic Advances in Medical Oncology 13
: 17588359211042301.
19 October 2021
A robust estimation of exon expression to identify alternative spliced genes applied to human tissues and cancer samples.
Risueño, A., Roson-Burgo, B., Dolnik, A., Hernandez-Rivas, J.M., Bullinger, L. and De Las Rivas, J.
BMC Genomics 15
: 879.
8 October 2014
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine.
Rivera, M., Fichtner, I., Wulf-Goldenberg, A., Sers, C., Merk, J., Patone, G., Alp, K.M., Kanashova, T., Mertins, P., Hoffmann, J., Stein, U. and Walther, W.
Neoplasia 23
(1): 21-35.
January 2021
Physical and functional interaction of the p14ARF tumor suppressor with ribosomes.
Rizos, H., McKenzie, H.A., Ayub, A.L., Woodruff, S., Becker, T.M., Scurr, L.L., Stahl, J. and Kefford, R.F.
Journal of Biological Chemistry 281
(49): 38080-38088.
8 December 2006
Instability of circular RNAs in clinical tissue samples impairs their reliable expression analysis using RT-qPCR: from the myth of their advantage as biomarkers to reality.
Rochow, H., Franz, A., Jung, M., Weickmann, S., Ralla, B., Kilic, E., Stephan, C., Fendler, A. and Jung, K.
Theranostics 10
(20): 9268-9279.
23 July 2020
Circular RNAs and their linear transcripts as diagnostic and prognostic tissue biomarkers in prostate cancer after prostatectomy in combination with clinicopathological factors.
Rochow, H., Jung, M., Weickmann, S., Ralla, B., Stephan, C., Elezkurtaj, S., Kilic, E., Zhao, Z., Jung, K., Fendler, A. and Franz, A.
International Journal of Molecular Sciences 21
(21): E7812.
22 October 2020
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms.
Rocks, O., Peyker, A., Kahms, M., Verveer, P.J., Koerner, C., Lumbierres, M., Kuhlmann, J., Waldmann, H., Wittinghofer, A. and Bastiaens, P.I.
Science 307
(5716): 1746-1752.
18 March 2005
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins.
Rocks, O., Gerauer, M., Vartak, N., Koch, S., Huang, Z.P., Pechlivanis, M., Kuhlmann, J., Brunsveld, L., Chandra, A., Ellinger, B., Waldmann, H. and Bastiaens, P.I.
Cell 141
(3): 458-471.
30 April 2010
Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors.
Rocks, O., Peyker, A. and Bastiaens, P.I.
Current Opinion in Cell Biology 18
(4): 351-357.
August 2006
Mutational topography reflects clinical neuroblastoma heterogeneity.
Rodriguez-Fos, E., Planas-Fèlix, M., Burkert, M., Puiggròs, M., Toedling, J., Thiessen, N., Blanc, E., Szymansky, A., Hertwig, F., Ishaque, N., Beule, D., Torrents, D., Eggert, A., Koche, R.P., Schwarz, R.F., Haase, K., Schulte, J.H. and Henssen, A.G.
Cell Genomics 3
(10): 100402.
11 October 2023
Multimodale Therapie des Rektumkarzinoms [Multimodality treatment for colorectal cancer].
Roedel, C., Hoehler, T., Sauer, R., Siewczynski, R., Flentje, M., Budach, V. and Schlag, P.M.
Onkologie 31
(Suppl 5): 24-28.
November 2008
Lef1 plays a role in patterning the mesoderm and ectoderm in Xenopus tropicalis.
Roel, G., Gent, Y.Y., Peterson-Maduro, J., Verbeek, F.J. and Destree, O.
International Journal of Developmental Biology 53
(1): 81-89.
2009
Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma.
Roeschert, I., Poon, E., Henssen, A.G., Dorado Garcia, H., Gatti, M., Giansanti, C., Jamin, Y., Ade, C.P., Gallant, P., Schülein-Völk, C., Beli, P., Richards, M., Rosenfeldt, M., Altmeyer, M., Anderson, J., Eggert, A., Dobbelstein, M., Bayliss, R., Chesler, L., Büchel, G. and Eilers, M.
Nature Cancer 2
(3): 312-326.
March 2021
OpenMS: a flexible open-source software platform for mass spectrometry data analysis.
Roest, H.L., Sachsenberg, T., Aiche, S., Bielow, C., Weisser, H., Aicheler, F., Andreotti, S., Ehrlich, H.C., Gutenbrunner, P., Kenar, E., Liang, X., Nahnsen, S., Nilse, L., Pfeuffer, J., Rosenberger, G., Rurik, M., Schmitt, U., Veit, J., Walzer, M., Wojnar, D., Wolski, W.E., Schilling, O., Choudhary, J.S., Malmstroem, L., Aebersold, R., Reinert, K. and Kohlbacher, O.
Nature Methods 13
(9): 741-748.
September 2016
The retinoblastoma protein modulates expression of genes coding for diverse classes of proteins including components of the extracellular matrix.
Rohde, M., Warthoe, P., Gjetting, T., Lukas, J., Bartek, J. and Strauss, M.
Oncogene 12
(11): 2393-2401.
6 June 1996
Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies.
Rohr, U.P., Herrmann, P., Ilm, K., Zhang, H., Lohmann, S., Reiser, A., Muranyi, A., Smith, J., Burock, S., Osterland, M., Leith, K., Singh, S., Brunhoeber, P., Bowermaster, R., Tie, J., Christie, M., Wong, H.L., Waring, P., Shanmugam, K., Gibbs, P. and Stein, U.
Annals of Oncology 28
(8): 1869-1875.
1 August 2017
Molecular flexibility in ab initio drug docking to DNA: binding-site and binding-mode transitions in all-atom Monte Carlo simulations.
Rohs, R., Bloch, I., Sklenar, H. and Shakked, Z.
Nucleic Acids Research 33
(22): 7048-7057.
13 December 2005
Unraveling proteins: A molecular mechanics study.
Rohs, R., Etchebest, C. and Lavery, R.
Biophysical Journal 76
(5): 2760-2768.
May 1999
Methylene blue binding to DNA with alternating AT base sequence: minor groove binding is favored over intercalation.
Rohs, R. and Sklenar, H.
Journal of Biomolecular Structure & Dynamics 21
(5): 699-712.
1 April 2004
Structural and energetic origins of sequence-specific DNA bending: Monte Carlo simulations of papillomavirus E2-DNA binding sites.
Rohs, R., Sklenar, H. and Shakked, Z.
Structure with Folding & Design 13
(10): 1499-1509.
1 October 2005
Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB.
Rohwer, N., Dame, C., Haugstetter, A.M., Wiedenmann, B., Detjen, K., Schmitt, C.A. and Cramer, T.
PLoS ONE 5
(8): e12038.
10 August 2010
HIF-1alpha determines the metastatic potential of gastric cancer cells.
Rohwer, N., Lobitz, S., Daskalow, K., Joens, T., Vieth, M., Schlag, P.M., Kemmner, W., Wiedenmann, B., Cramer, T. and Hoecker, M.
British Journal of Cancer 100
(5): 772-781.
10 March 2009
Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.
Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K.T., Fragoulis, At., Kühl, A.A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C.E., Brenner, W., Malinowski, M.B., Stockmann, M., Schomburg, L., Faller, W., Sansom, O.J., Tacke, F., Morkel, M. and Cramer, T.
Oncogene 38
(28): 5670-5685.
11 July 2019
Response of patient-derived non-small cell lung cancer xenografts to classical and targeted therapies is not related to multidrug resistance markers.
Rolff, J., Dorn, C., Merk, J. and Fichtner, I.
Journal of Oncology 2009
: 814140.
2009
Induction of PSA-specific CTLs and anti-tumor immunity by a genetic prostate cancer vaccine.
Roos, A.K., Pavlenko, M., Charo, J., Egevad, L. and Pisa, P.
Prostate 62
(3): 217-223.
1 January 2005
The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42.
Rosario, M., Franke, R., Bednarski, C. and Birchmeier, W.
Journal of Cell Biology 178
(3): 503-516.
30 July 2007
Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.
Rosario, M., Schuster, S., Juettner, R., Parthasarathy, S., Tarabykin, V. and Birchmeier, W.
Genes & Development 26
(15): 1743-1757.
1 August 2012
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
Rosenbauer, F., Owens, B.M., Yu, L., Tumang, J.R., Steidl, U., Kutok, J.L., Clayton, L.K., Wagner, K., Scheller, M., Iwasaki, H., Liu, C., Hackanson, B., Akashi, K., Leutz, A., Rothstein, T.L., Plass, C. and Tenen, D.G.
Nature Genetics 38
(1): 27-37.
January 2006
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.
Rosenbauer, F., Wagner, K., Kutok, J.L., Iwasaki, H., Le Beau, M.M., Okuno, Y., Akashi, K., Fiering, S. and Tenen, D.G.
Nature Genetics 36
: 624-630.
1 June 2004
pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1.
Rosenbauer, F., Wagner, K., Zhang, P., Knobeloch, K.P., Iwama, A. and Tenen, D.G.
Blood 103
: 4294-4301.
1 June 2004
JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia.
Rosenberg, J.M., Peters, J.M., Hughes, T., Lareau, C.A., Ludwig, L.S., Massoth, L.R., Austin-Tse, C., Rehm, H.L., Bryson, B., Chen, Y.B., Regev, A., Shalek, A.K., Fortune, S.M. and Sykes, D.B.
Med 3
(1): 42-57.e5.
14 January 2022
High-resolution crystal structures of Caldicellulosiruptor strain Rt8B.4 carbohydrate-binding module CBM27-1 and its complex with mannohexaose.
Roske, Y., Sunna, A., Pfeil, W. and Heinemann, U.
Journal of Molecular Biology 340
(3): 543-554.
9 July 2004
Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Roske, Y., Cappel, C., Cremer, N., Hoffmann, P., Koudelka, T., Tholey, A., Heinemann, U., Daumke, O. and Damme, M.
Nucleic Acids Research 52
(1): 370-384.
11 January 2024
TapA acts as specific chaperone in TasA filament formation by strand complementation.
Roske, Y., Lindemann, F., Diehl, A., Cremer, N., Higman, V.A., Schlegel, B., Leidert, M., Driller, K., Turgay, K., Schmieder, P., Heinemann, U. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 120
(17): e2217070120.
25 April 2023
Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold.
Rossbach, M., Daumke, O., Klinger, C., Wittinghofer, A. and Kaufmann, M.
BMC Structural Biology 5
: 7.
20 March 2005
TCRs are randomly distributed on the plasma membrane of resting antigen-experienced T cells.
Rossboth, B., Arnold, A.M., Ta, H., Platzer, R., Kellner, F., Huppa, J.B., Brameshuber, M., Baumgart, F. and Schütz, G.J.
Nature Immunology 19
(8): 821-827.
August 2018
Crystal structures of human saposins C and D: implications for lipid recognition and membrane interactions.
Rossmann, M., Schultz-Heienbrok, R., Behlke, J., Remmel, N., Alings, C., Sandhoff, K., Saenger, W. and Maier, T.
Structure 16
(5): 809-817.
7 May 2008
Shp-2 is dispensable for establishing T cell exhaustion and for PD-1 signaling in vivo.
Rota, G., Niogret, C., Dang, A.T., Barros, C.R., Fonta, N.P., Alfei, F., Morgado, L., Zehn, D., Birchmeier, W., Vivier, E. and Guarda, G.
Cell Reports 23
(1): 39-49.
3 April 2018
IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis.
Rothe, M., Quarcoo, D., Chashchina, A.A., Bozrova, S.V., Qin, Z., Nedospasov, S.A., Blankenstein, T., Kammertoens, T. and Drutskaya, M.S.
Cancer Medicine 2
(6): 815-825.
December 2013
Phantom phenomena in mastectomized patients and their relation to chronic and acute pre-mastectomy pain.
Rothemund, Y., Gruesser, S.M., Liebeskind, U., Schlag, P.M. and Flor, H.
Pain 107
(1-2): 140-146.
1 January 2004
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants.
Rothenberger, S., Hurdiss, D.L., Walser, M., Malvezzi, F., Mayor, J., Ryter, S., Moreno, H., Liechti, N., Bosshart, A., Iss, C., Calabro, V., Cornelius, A., Hospodarsch, T., Neculcea, A., Looser, T., Schlegel, A., Fontaine, S., Villemagne, D., Paladino, M., Schiegg, D., Mangold, S., Reichen, C., Radom, F., Kaufmann, Y., Schaible, D., Schlegel, I., Zitt, C., Sigrist, G., Straumann, M., Wolter, J., Comby, M., Sacarcelik, F., Drulyte, I., Lyoo, H., Wang, C., Li, W., Du, W., Binz, H.K., Herrup, R., Lusvarghi, S., Neerukonda, S.N., Vassell, R., Wang, W., Adler, J.M., Eschke, K., Nascimento, M., Abdelgawad, A., Gruber, A.D., Bushe, J., Kershaw, O., Knutson, C.G., Balavenkatraman, K.K., Ramanathan, K., Wyler, E., Teixeira Alves, L.G., Lewis, S., Watson, R., Haeuptle, M.A., Zürcher, A., Dawson, K.M., Steiner, D., Weiss, C.D., Amstutz, P., van Kuppeveld, F.J.M., Stumpp, M.T., Bosch, B.J., Engler, O. and Trimpert, J.
Nature Biotechnology 40
(12): 1845-1854.
December 2022
Combined human genome-wide RNAi and metabolite analyses identify IMPDH as a host-directed target against Chlamydia infection.
Rother, M., Gonzalez, E., Teixeira da Costa, A.R., Wask, L., Gravenstein, I., Pardo, M., Pietzke, M., Gurumurthy, R.K., Angermann, J., Laudeley, R., Glage, S., Meyer, M., Chumduri, C., Kempa, S., Dinkel, K., Unger, A., Klebl, B., Klos, A. and Meyer, T.F.
Cell Host & Microbe 23
(5): 661-671.
9 May 2018
Prospective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells.
Rouhi, A., Miller, C., Grasedieck, S., Reinhart, S., Stolze, B., Döhner, H., Kuchenbauer, F., Bullinger, L., Fröhling, S. and Scholl, C.
Oncotarget 8
(5): 7678-7690.
31 January 2017
CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A., Qadri, F., Leukel, L., Yilmaz, R., Fontaine, J.F., Sihn, G., Bader, M., Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123
(3): 1343-1347.
1 March 2013
CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Rousselle, A., Sonnemann, J., Amann, K., Mildner, A., Lodka, D., Kling, L., Bieringer, M., Schneider, U., Leutz, A., Enghard, P., Kettritz, R. and Schreiber, A.
Annals of the Rheumatic Diseases 81
(8): 1162-1172.
August 2022
The answer's in the tail: MYC mRNA has a metabolic sensor that supports cancer chemoresistance.
Royla, N. and Kempa, S.
Molecular & Cellular Oncology 4
(4): e1338209.
5 July 2017
Low temperature FTIR spectra and hydrogen bonds in polycrystalline adenosine and uridine.
Rozenberg, M., Jung, C. and Shoham, G.
Spectrochimica Acta, A Molecular and Biomolecular Spectroscopy 61
(4): 733-741.
February 2005
Low temperature FTIR spectra and hydrogen bonds in polycrystalline cytidine.
Rozenberg, M., Jung, C. and Shoham, G.
Spectrochimica Acta, A Molecular and Biomolecular Spectroscopy 60
(10): 2369-2375.
1 January 2004
Ordered and disordered hydrogen bonds in adenosine, cytidine and uridine studied by low temperature FT infrared spectroscopy.
Rozenberg, M., Jung, C. and Shoham, G.
Physical Chemistry, Chemical Physics 5
(8): 1533-1535.
2003
Quantification of mRNA expression using single-molecule nanopore sensing.
Rozevsky, Y., Gilboa, T., van Kooten, X.F., Kobelt, D., Huttner, D., Stein, U. and Meller, A.
ACS Nano 14
(10): 13964-13974.
27 October 2020
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
Rozman, J., Rathkolb, B., Oestereicher, M.A., Schütt, C., Ravindranath, A.C., Leuchtenberger, S., Sharma, S., Kistler, M., Willershäuser, M., Brommage, R., Meehan, T.F., Mason, J., Haselimashhadi, H., Hough, T., Mallon, A.M., Wells, S., Santos, L., Lelliott, C.J., White, J.K., Sorg, T., Champy, M.F., Bower, L.R., Reynolds, C. L., Flenniken, A.M., Murray, St.A., Nutter, L.M.J., Svenson, K.L., West, D., Tocchini-Valentini, G.P., Beaudet, A.L., Bosch, F., Braun, R.B., Dobbie, M.S., Gao, X., Herault, Y., Moshiri, A., Moore, B.A., Kent Lloyd, K.C., McKerlie, C., Masuya, H., Tanaka, N., Flicek, P., Parkinson, H.E., Sedlacek, R., Seong, J.K., Wang, C.K.L., Moore, M., Brown, S.D., Tschöp, M.H., Wurst, W., Klingenspor, M., Wolf, E., Beckers, J., Machicao, F., Peter, A., Staiger, H., Häring, H.U., Grallert, H., Campillos, M., Maier, H., Fuchs, H., Gailus-Durner, V., Werner, T. and Hrabe de Angelis, M.
Nature Communications 9
(1): 288.
18 January 2018
Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T., Meyer, K., Roske, Y., Uyar, B., Akalin, A., Imami, K., Ishihama, Y., Daumke, O. and Selbach, M.
Nature Communications 15
(1): 3146.
11 April 2024
Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-gamma.
Rubio, M.T., Kim, Y.M., Sachs, T., Mapara, M., Zhao, G. and Sykes, M.
Blood 102
: 2300-2307.
15 September 2003
Ron Estabrook - a catalyst of scientific interactions between East and West.
Ruckpaul, K. and Renneberg, R.
Drug Metabolism Reviews 39
(2-3): 267-270.
2007
RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia.
Rudat, S., Pfaus, A., Cheng, Y.Y., Holtmann, J., Ellegast, J.M., Bühler, C., Marcantonio, D.D., Martinez, E., Göllner, S., Wickenhauser, C., Müller-Tidow, C., Lutz, C., Bullinger, L., Milsom, M.D., Sykes, S.M., Fröhling, S. and Scholl, C.
Leukemia 32
(10): 2189-2202.
October 2018
Type I and type II reactions in TRAIL-induced apoptosis - results from dose-response studies.
Rudner, J., Jendrossek, V., Lauber, K., Daniel, P.T., Wesselborg, S. and Belka, C.
Oncogene 24
: 130-140.
6 January 2005
EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with Snapin.
Rueder, C., Reimer, T., Delgado-Martinez, I., Hermosilla, R., Engelsberg, A., Nehring, R., Doerken, B. and Rehm, A.
Molecular Biology of the Cell 16
(3): 1245-1257.
5 January 2005
The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.
Rueder, C., Höpken, U.E., Wolf, J., Mittruecker, H.W., Engels, B., Erdmann, B., Wollenzin, S., Uckert, W., Dörken, B. and Rehm, A.
Journal of Clinical Investigation 119
(8): 2184-2203.
August 2009
Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Ruess, D.A., Heynen, G.J., Ciecielski, K.J., Ai, J., Berninger, A., Kabacaoglu, D., Görgülü, K., Dantes, Z., Wörmann, S.M., Diakopoulos, K.N., Karpathaki, A.F., Kowalska, M., Kaya-Aksoy, E., Song, L., Zeeuw van der Laan, E.A., López-Alberca, M.P., Nazaré, M., Reichert, M., Saur, D., Erkan, M.M., Hopt, U.T., Sainz, B., Birchmeier, W., Schmid, R.M., Lesina, M. and Algül, H.
Nature Medicine 24
(7): 954-960.
July 2018
The plakoglobin knock-out mouse: A paradigm for the molecular analysis of cardiac cell junction formation.
Ruiz, P. and Birchmeier, W.
Trends in Cardiovascular Medicine 8
(3): 97-101.
April 1998
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
Ruiz, P., Brinkmann, V., Ledermann, B., Behrend, M., Grund, C., Thalhammer, C., Vogel, F., Birchmeier, C., Guenthert, U., Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 135
(1): 215-225.
October 1996
Stroma-mediated dysregulation of myelopoiesis in mice lacking IkappaBalpha.
Rupec, R.A., Jundt, F., Rebholz, B., Eckelt, B., Weindl, G.N., Herzinger, T., Flaig, M.J., Moosmann, S., Plewig, G., Doerken, B., Foerster, I., Huss, R. and Pfeffer, K.
Immunity 22
: 479-491.
1 January 2005
Distinct changes in gene expression induced by A-Myb, B-Myb and c-Myb proteins.
Rushton, J.J., Davis, L.M., Lei, W.L., Mo, X.M., Leutz, A. and Ness, S.A.
Oncogene 22
(2): 308-313.
16 January 2003
Mapping the transglycosylation relevant sites of cold-adapted β-d-galactosidase from arthrobacter sp. 32cB.
Rutkiewicz, M., Wanarska, M. and Bujacz, A.
International Journal of Molecular Sciences 21
(15): 5354.
28 July 2020
Detection of broadly expressed neuronal genes in C. elegans.
Ruvinsky, I., Ohler, U., Burge, C.B. and Ruvkun, G.
Developmental Biology 302
(2): 617-626.
15 February 2007
Chromosomal instability during neurogenesis in Huntington's disease.
Ruzo, A., Croft, G.F., Metzger, J.J., Galgoczi, S., Gerber, L.J., Pellegrini, C., Wang, H., Fenner, M., Tse, S., Marks, A., Nchako, C. and Brivanlou, A.H.
Development 145
(2)
January 2018
Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.
Rybak-Wolf, A., Wyler, E., Pentimalli, T.M., Legnini, I., Oliveras Martinez, A., Glažar, P., Loewa, A., Kim, S.J., Kaufer, B.B., Woehler, A., Landthaler, M. and Rajewsky, N.
Nature Microbiology 8
(7): 1252-1266.
July 2023
In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3.
Ryppa, C., Mann-Steinberg, H., Fichtner, I., Weber, H., Satchi-Fainaro, R., Biniossek, M.L. and Kratz, F.
Bioconjugate Chemistry 19
(7): 1414-1422.
July 2008
Measurable residual disease monitoring in AML with FLT3-ITD treated with intensive chemotherapy plus midostaurin.
Rücker, F.G., Bullinger, L., Cocciardi, S., Skambraks, S., Luck, T.J., Weber, D., Krzykalla, J., Pozek, E., Schneider, I.J., Corbacioglu, A., Gaidzik, V.I., Meid, A., Aicher, S., Stegelmann, F., Schrade, A., Theis, F., Fiedler, W., Salih, H.R., Wulf, G.G., Salwender, H.J., Schroeder, T., Götze, K.S., Kühn, M.W.M., Lübbert, M., Schlenk, R.F., Benner, A., Thol, F.R., Heuser, M., Ganser, A., Döhner, H. and Döhner, K.
Blood Advances 8
(23): 6067-6080.
10 December 2024
Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group.
Rücker, F.G., Agrawal, M., Corbacioglu, A., Weber, D., Kapp-Schwoerer, S., Gaidzik, V.I., Jahn, N., Schroeder, T., Wattad, M., Lübbert, M., Koller, E., Kindler, T., Götze, K., Ringhoffer, M., Westermann, J., Fiedler, W., Horst, H.A., Greil, R., Schroers, R., Mayer, K., Heinicke, T., Krauter, J., Schlenk, R.F., Thol, F., Heuser, M., Ganser, A., Bullinger, L., Paschka, P., Döhner, H. and Döhner, K.
Blood 134
(19): 1608-1618.
7 November 2019
Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
Rücker, F.G., Du, L., Luck, T.J., Benner, A., Krzykalla, J., Gathmann, I., Voso, M.T., Amadori, S., Prior, T.W., Brandwein, J.M., Appelbaum, F.R., Medeiros, B.C., Tallman, M.S., Savoie, L., Sierra, J., Pallaud, C., Sanz, M.A., Jansen, J.H., Niederwieser, D., Fischer, T., Ehninger, G., Heuser, M., Ganser, A., Bullinger, L., Larson, R.A., Bloomfield, C.D., Stone, R.M., Döhner, H., Thiede, C. and Döhner, K.
Leukemia 36
(1): 90-99.
January 2022
Molecular dissection of valproic acid effects in acute myeloid leukemia identifies predictive networks.
Rücker, F.G., Lang, K.M., Fütterer, M., Komarica, V., Schmid, M., Döhner, H., Schlenk, R.F., Döhner, K., Knudsen, S. and Bullinger, L.
Epigenetics 11
(7): 517-525.
2 July 2016
Clonal expansion and epigenetic inheritance of long-lasting NK cell memory.
Rückert, T., Lareau, C.A., Mashreghi, M.F., Ludwig, L.S. and Romagnani, C.
Nature Immunology 23
(11): 1551-1563.
November 2022
Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Sachs, M., Brohmann, H., Zechner, D., Mueller, T., Huelsken, J., Walther, I., Schaeper, U., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 150
(6): 1375-1384.
18 September 2000
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases.
Sachs, M., Weidner, K.M., Brinkmann, V., Walther, I., Obermeier, A., Ullrich, A. and Birchmeier, W.
Journal of Cell Biology 133
(5): 1095-1107.
3 June 1996
RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.
Sachs, R., Max, K.E., Heinemann, U. and Balbach, J.
RNA 18
(1): 65-76.
January 2012
Wnt up your mind - intervention strategies for S100A4-induced metastasis in colon cancer.
Sack, U. and Stein, U.
General Physiology and Biophysics 28
(Focus Iss): F55-F64.
December 2009
S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells.
Sack, U., Walther, W., Scudiero, D., Selby, M., Aumann, J., Lemos, C., Fichtner, I., Schlag, P.M., Shoemaker, R.H. and Stein, U.
Molecular Biology of the Cell 22
(18): 3344-3354.
September 2011
Novel effect of antihelminthic niclosamide on S100A4-mediated metastatic progression in colon cancer.
Sack, U., Walther, W., Scudiero, D., Selby, M., Kobelt, D., Lemm, M., Fichtner, I., Schlag, P.M., Shoemaker, R.H. and Stein, U.
Journal of the National Cancer Institute 103
(13): 1018-1036.
6 July 2011
Decreased expression of angiogenesis antagonist EFEMP1 in sporadic breast cancer is caused by aberrant promoter methylation and points to an impact of EFEMP1 as molecular biomarker.
Sadr-Nabavi, A., Ramser, J., Volkmann, J., Naehrig, J., Wiesmann, F., Betz, B., Hellebrand, H., Engert, S., Seitz, S., Kreutzfeld, R., Sasaki, T., Arnold, N., Schmutzler, R., Kiechle, M., Niederacher, D., Harbeck, N., Dahl, E. and Meindl, A.
International Journal of Cancer 124
(7): 1727-1735.
1 April 2009
Suppression of polyploidy by the BRCA2 protein.
Sagulenko, E., Savelyeva, L., Ehemann, V., Sagulenko, V., Hofmann, W., Arnold, K., Claas, A., Scherneck, S. and Schwab, M.
Cancer Letters 257
(1): 65-72.
8 November 2007
Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer.
Saini, M., Schmidleitner, L., Moreno, H.D., Donato, E., Falcone, M., Bartsch, J.M., Vogel, V., Würth, R., Pfarr, N., Espinet, E., Lehmann, M., Königshoff, M., Reitberger, M., Haas, S., Graf, E., Schwarzmayr, T., Strom, T.M., Spaich, S., Sütterlin, M., Schneeweiss, A., Weichert, W., Schotta, G., Reichert, M., Aceto, N., Sprick, M.R., Trumpp, A., Scheel, C.H. and Klein, C.
Cell Reports 42
(6): 112533.
27 June 2023
Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis.
Sakai, N., Wada, T., Yokoyama, H., Lipp, M., Ueha, S., Matsushima, K. and Kaneko, S.
Proceedings of the National Academy of Sciences of the United States of America 103
(38): 14098-14103.
19 September 2006
Regulatory T cells in transplantation: does extracellular adenosine triphosphate metabolism through CD39 play a crucial role?
Salcido-Ochoa, F., Tsang, J., Tam, P., Falk, K. and Roetzschke, O.
Transplantation Reviews 24
(2): 52-66.
April 2010
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.
Sallusto, F., Lenig, D., Foerster, R., Lipp, M. and Lanzavecchia, A.
Nature 401
(6754): 708-712.
14 October 1999
Solution structure and backbone dynamics of the Trypanosoma cruzi cysteine protease inhibitor chagasin.
Salmon, D., Aido-Machado, R., Diehl, A., Leidert, M., Schmetzer, O., de Lima, A.P., Scharfstein, J., Oschkinat, H. and Pires, J.R.
Journal of Molecular Biology 357
(5): 1511-1521.
14 April 2006
Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function.
Salzer, B., Schueller, C.M., Zajc, C.U., Peters, T., Schoeber, M.A., Kovacic, B., Buri, M.C., Lobner, E., Dushek, O., Huppa, J.B., Obinger, C., Putz, E.M., Holter, W., Traxlmayr, M.W. and Lehner, M.
Nature Communications 11
(1): 4166.
20 August 2020
RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.
Salzer, E., Cagdas, D., Hons, M., Mace, E.M., Garncarz, W., Petronczki, Ö.Y., Platzer, R., Pfajfer, L., Bilic, I., Ban, S.A., Willmann, K.L., Mukherjee, M., Supper, V., Hsu, H.T., Banerjee, P.P., Sinha, P., McClanahan, F., Zlabinger, G.J., Pickl, W.F., Gribben, J.G., Stockinger, H., Bennett, K.L., Huppa, J.B., Dupré, L., Sanal, Ö., Jäger, U., Sixt, M., Tezcan, I., Orange, J.S. and Boztug, K.
Nature Immunology 17
(12): 1352-1360.
December 2016
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity.
Salzer, E., Zoghi, S., Kiss, M.G., Kage, F., Rashkova, C., Stahnke, S., Haimel, M., Platzer, R., Caldera, M., Ardy, R.C., Hoeger, B., Block, J., Medgyesi, D., Sin, C., Shahkarami, S., Kain, R., Ziaee, V., Hammerl, P., Bock, C., Menche, J., Dupré, L., Huppa, J.B., Sixt, M., Lomakin, A., Rottner, K., Binder, C.J., Stradal, T.E.B., Rezaei, N. and Boztug, K.
Science Immunology 5
(49): eabc3979.
10 July 2020
KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in Plasmodium falciparum-infected erythrocytes.
Sanchez, C.P., Patra, P., Chang, S.Y.S., Karathanasis, C., Hanebutte, L., Kilian, N., Cyrklaff, M., Heilemann, M., Schwarz, U.S., Kudryashev, M. and Lanzer, M.
Molecular Microbiology 117
(2): 274-292.
February 2022
Subnanometer-resolution structure determination in situ by hybrid subtomogram averaging - single particle cryo-EM.
Sanchez, R.M., Zhang, Y., Chen, W., Dietrich, L. and Kudryashev, M.
Nature Communications 11
(1): 3709.
24 July 2020
The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily.
Sanchez-Pulido, L. and Andrade-Navarro, M.A.
BMC Biochemistry 8
: 23.
8 November 2007
Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.
Sander, S., Calado, D.P., Srinivasan, L., Köchert, K., Zhang, B., Rosolowski, M., Rodig, S.J., Holzmann, K., Stilgenbauer, S., Siebert, R., Bullinger, L. and Rajewsky, K.
Cancer Cell 22
(2): 167-179.
14 August 2012
PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones.
Sander, S., Chu, V.T., Yasuda, T., Franklin, A., Graf, R., Calado, D.P., Li, S., Imami, K., Selbach, M., Di Virgilio, M., Bullinger, L. and Rajewsky, K.
Immunity 43
(6): 1075-1086.
15 December 2015
Single-cell template strand sequencing by strand-seq enables the characterization of individual homologs.
Sanders, A.D., Falconer, E., Hills, M., Spierings, D.C.J. and Lansdorp, P.M.
Nature Protocols 12
(6): 1151-1176.
June 2017
Characterizing polymorphic inversions in human genomes by single-cell sequencing.
Sanders, A.D., Hills, M., Porubský, D., Guryev, V., Falconer, E. and Lansdorp, P.M.
Genome Research 26
(11): 1575-1587.
November 2016
Single-cell analysis of structural variations and complex rearrangements with tri-channel processing.
Sanders, A.D., Meiers, S., Ghareghani, M., Porubsky, D., Jeong, H., van Vliet, M.A.C.C., Rausch, T., Richter-Pechańska, P., Kunz, J.B., Jenni, S., Bolognini, D., Longo, G.M.C., Raeder, B., Kinanen, V., Zimmermann, J., Benes, V., Schrappe, M., Mardin, B.R., Kulozik, A.E., Bornhauser, B., Bourquin, J.P., Marschall, T. and Korbel, J.O.
Nature Biotechnology 38
(3): 343-354.
March 2020
Gene transfer into hepatocytes and human liver tissue by baculovirus vectors.
Sandig, V., Hofmann, C., Steinert, S., Jennings, G., Schlag, P.M. and Strauss, M.
Human Gene Therapy 7
(16): 1937-1945.
20 October 1996
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.
Sankaran, V.G., Ludwig, L.S., Sicinska, E., Xu, J., Bauer, D.E., Eng, J.C., Patterson, H.C., Metcalf, R.A., Natkunam, Y., Orkin, S.H., Sicinski, P., Lander, E.S. and Lodish, H.F.
Genes & Development 26
(18): 2075-2087.
15 September 2012
X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation.
Sankaran, V.G., Ulirsch, J.C., Tchaikovskii, V., Ludwig, L.S., Wakabayashi, A., Kadirvel, S., Lindsley, R.C., Bejar, R., Shi, J., Lovitch, S.B., Bishop, D.F. and Steensma, D.P.
Journal of Clinical Investigation 125
(4): 1665-1669.
1 April 2015
Identification of environmental factors that promote intestinal inflammation.
Sanmarco, L.M., Chao, C.C., Wang, Y.C., Kenison, J.E., Li, Z., Rone, J.M., Rejano-Gordillo, C.M., Polonio, C.M., Gutierrez-Vazquez, C., Piester, G., Plasencia, A., Li, L., Giovannoni, F., Lee, H.G., Faust Akl, C., Wheeler, M.A., Mascanfroni, I., Jaronen, M., Alsuwailm, M., Hewson, P., Yeste, A., Andersen, B.M., Franks, D.G., Huang, C.J., Ekwudo, M., Tjon, E.C., Rothhammer, V., Takenaka, M., de Lima, K.A., Linnerbauer, M., Guo, L., Covacu, R., Queva, H., Fonseca-Castro, P.H., Bladi, M.A., Cox, L.M., Hodgetts, K.J., Hahn, M.E., Mildner, A., Korzenik, J., Hauser, R., Snapper, S.B. and Quintana, F.J.
Nature 611
(7937): 801-809.
24 November 2022
A knowledge graph to interpret clinical proteomics data.
Santos, A., Colaço, A.R., Nielsen, A.B., Niu, L., Strauss, M., Geyer, P.E., Coscia, F., Albrechtsen, N.J.W., Mundt, F., Jensen, L.J. and Mann, M.
Nature Biotechnology 40
(5): 692-702.
22 May 2022
SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia.
Sasca, D., Hähnel, P.S., Szybinski, J., Khawaja, K., Kriege, O., Pante, S.V., Bullinger, L., Strand, S., Strand, D., Theobald, M. and Kindler, T.
Blood 124
(1): 121-133.
3 July 2014
NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML.
Sasca, D., Szybinski, J., Schüler, A., Shah, V., Heidelberger, J., Haehnel, P.S., Dolnik, A., Kriege, O., Fehr, E.M., Gebhardt, W.H., Reid, G., Scholl, C., Theobald, M., Bullinger, L., Beli, P. and Kindler, T.
Blood 133
(21): 2305-2319.
23 May 2019
Basal delamination during mouse gastrulation primes pluripotent cells for differentiation.
Sato, N., Rosa, V.S., Makhlouf, A., Kretzmer, H., Sampath Kumar, A., Grosswendt, S., Mattei, A.L., Courbot, O., Wolf, S., Boulanger, J., Langevin, F., Wiacek, M., Karpinski, D., Elosegui-Artola, A., Meissner, A., Zernicka-Goetz, M. and Shahbazi, M.N.
Developmental Cell 59
(10): 1252-1268.
20 May 2024
Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain.
Saupe, J., Roske, Y., Schillinger, C., Kamdem, N., Radetzki, S., Diehl, A., Oschkinat, H., Krause, G., Heinemann, U. and Rademann, J.
ChemMedChem 6
(8): 1411-1422.
1 August 2011
Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML-Study IV.
Saussele, S., Krauss, M.P., Hehlmann, R., Lauseker, M., Proetel, U., Kalmanti, L., Hanfstein, B., Fabarius, A., Kraemer, D., Berdel, W.E., Bentz, M., Staib, P., de Wit, M., Wernli, M., Zettl, F., Hebart, H.F., Hahn, M., Heymanns, J., Schmidt-Wolf, I., Schmitz, N., Eckart, M.J., Gassmann, W., Bartholomaeus, A., Pezzutto, A., Oppliger Leibundgut, E., Heim, D., Krause, S.W., Burchert, A., Hofmann, W.K., Hasford, J., Hochhaus, A., Pfirrmann, M. and Müller, M.C.
Blood 126
(1): 42-49.
2 July 2015
An interstitial tandem duplication of 9p23-24 coexists with a mutation in the BRCA2 gene in the germ line of three brothers with breast cancer.
Savelyeva, L., Claas, A., Gier, S., Schlag, P.M., Finke, L., Mangion, J., Stratton, M.R. and Schwab, M.
Cancer Research 58
(5): 863-866.
1 March 1998
Constitutional genomic instability with inversions, duplications, and amplifications in 9p23-24 in BRCA2 mutation carriers.
Savelyeva, L., Claas, A., Matzner, I., Schlag, P.M., Hofmann, W., Scherneck, S., Weber, B. and Schwab, M.
Cancer Research 61
: 5179-5185.
1 January 2001
The prognostic significance of antigen expression in leukaemia.
Schabath, R., Ratei, R. and Ludwig, W.D.
Best Practice & Research in Clinical Haematology 16
: 613-628.
1 December 2003
Loss of Gadkin affects dendritic cell migration in vitro.
Schachtner, H., Weimershaus, M., Stache, V., Plewa, N., Legler, D.F., Höpken, U.E. and Maritzen, T.
PLoS ONE 10
(12): e0143883.
1 December 2015
Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo.
Schadendorf, D., Kern, M.A., Artuc, M., Pahl, H.L., Rosenbach, T., Fichtner, I., Nuernberg, W., Stueting, S., von Stebut, E., Worm, M., Makki, A., Jurgovsky, K., Kolde, G. and Henz, B.M.
Journal of Cell Biology 135
(6 Pt 2): 1889-1898.
December 1996
Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1-and Sp3-dependent activation of two proximal GC-rich promoter elements.
Schaefer, G., Cramer, T., Suske, G., Kemmner, W., Wiedenmann, B. and Hoecker, M.
Journal of Biological Chemistry 278
(10): 8190-8198.
7 March 2003
HIPPIE: integrating protein interaction networks with experiment based quality scores.
Schaefer, M.H., Fontaine, J.F., Vinayagam, A., Porras, P., Wanker, E.E. and Andrade-Navarro, M.A.
PLoS ONE 7
(2): e31826.
14 February 2012
Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.
Schaefer, M.H., Lopes, T.J.S., Mah, N., Shoemaker, J.E., Matsuoka, Y., Fontaine, J.F., Louis-Jeune, C., Eisfeld, A.J., Neumann, G., Perez-Iratxeta, C., Kawaoka, Y., Kitano, H. and Andrade-Navarro, M.A.
PLoS Computational Biology 9
(1): e1002860.
3 January 2013
Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Schaefer, M.H., Wanker, E.E. and Andrade-Navarro, M.A.
Nucleic Acids Research 40
(10): 4273-4287.
1 May 2012
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
Schaeper, U., Gehring, N.H., Fuchs, K.P., Sachs, M., Kempkes, B. and Birchmeier, W.
Journal of Cell Biology 149
(7): 1419-1432.
26 June 2000
Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Schaeper, U., Vogel, R., Chmielowiec, J., Huelsken, J., Rosario, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104
(39): 15376-15381.
25 September 2007
CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function.
Schaerli, P., Willimann, K., Lang, A.B., Lipp, M., Loetscher, P. and Moser, B.
Journal of Experimental Medicine 192
(11): 1553-1562.
4 December 2000
Antitumor activity of a dual cytokine/single-chain antibody fusion protein for simultaneous delivery of GM-CSF and IL-2 to Ep-CAM expressing tumor cells.
Schanzer, J.M., Fichtner, I., Baeuerle, P.A. and Kufer, P.
Journal of Immunotherapy 29
(5): 477-488.
September 2006
Rapid multiplex analysis of lipid raft components with single-cell resolution.
Schatzlmaier, P., Supper, V., Göschl, L., Zwirzitz, A., Eckerstorfer, P., Ellmeier, W., Huppa, J.B. and Stockinger, H.
Science Signaling 8
(395): rs11.
September 2015
Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS).
Scheer, M., Blank, B., Bauer, S., Vokuhl, C., Stegmaier, S., Feuchtgruber, S., Henssen, A., Sparber-Sauer, M., Eggert, A., Handgretinger, R., Pekrun, A., Rossig, C., Rutkowski, S., Schlegel, P.G., Schrappe, M., Simon, T., Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Jahnukainen, K., Fuchs, J., Bielack, S.S., Koscielniak, E. and Klingebiel, T.
Journal of Cancer Research and Clinical Oncology 146
(4): 953-960.
April 2020
Pre-operative radiotherapy is associated with superior local relapse-free survival in advanced synovial sarcoma.
Scheer, M., Hallmen, E., Vokuhl, C., Fuchs, J., Tunn, P.U., Münter, M., Timmermann, B., Bauer, S., Henssen, A.G., Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Eggert, A., Klingebiel, T. and Koscielniak, E.
Journal of Cancer Research and Clinical Oncology 149
(5): 1717-1731.
May 2023
The effect of adjuvant therapies on long-term outcome for primary resected synovial sarcoma in a series of mainly children and adolescents.
Scheer, M., Vokuhl, C., Bauer, S., Fuchs, J., Loff, S., Timmermann, B., Münter, M., Henssen, A.G., Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Koscielniak, E. and Klingebiel, T.
Journal of Cancer Research and Clinical Oncology 147
(12): 3735-3747.
December 2021
IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
Scheffold, A., Jebaraj, B.M.C., Tausch, E., Bloehdorn, J., Ghia, P., Yahiaoui, A., Dolnik, A., Blätte, T.J., Bullinger, L., Dheenadayalan, R.P., Li, L., Schneider, C., Chen, S.S., Chiorazzi, N., Dietrich, S., Seiffert, M., Tannheimer, S., Döhner, H., Mertens, D. and Stilgenbauer, S.
Blood 134
(6): 534-547.
8 August 2019
Vectors for co-expression of an unrestricted number of proteins.
Scheich, C., Kuemmel, D., Soumailakakis, D., Heinemann, U. and Buessow, K.
Nucleic Acids Research 35
(6): e43.
March 2007
The pathogenetic significance of deregulated signal transduction pathways in Hodgkin's disease: the NF-kappaB-AP-1 network.
Scheidereit, C.
Verhandlungen der Deutschen Gesellschaft fuer Pathologie 87
: 79-89.
1 January 2003
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
Scheller, M., Huelsken, J., Rosenbauer, F., Taketo, M.M., Birchmeier, W., Tenen, D.G. and Leutz, A.
Nature Immunology 7
(10): 1037-1047.
October 2006
Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance.
Scheller, M., Schönheit, J., Zimmermann, K., Leser, U., Rosenbauer, F. and Leutz, A.
Journal of Experimental Medicine 210
(11): 2239-2256.
21 October 2013
Targeted tumor therapy with a fusion Protein of an antiangiogenic human recombinant scFv and yeast cytosine deaminase.
Schellmann, N., Panjideh, H., Fasold, P., Bachran, D., Bachran, C., Deckert, P.M. and Fuchs, H.
Journal of Immunotherapy 35
(7): 570-578.
September 2012
Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors.
Schelwies, K., Sturm, I., Grabowski, P., Scherubl, H., Schindler, I., Hermann, S., Stein, H., Buhr, H.J., Riecken, E.O., Zeitz, M., Doerken, B. and Daniel, P.T.
International Journal of Cancer 99
(4): 589-596.
1 June 2002
Brustkrebs bei Frauen mit Down-Syndrom.
Scherneck, S. and Jandrig, B.
Leben mit Down-Syndrom 50
: 38-39.
2005
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
Schick, M., Zhang, L., Maurer, S., Maurer, H.C., Isaakaidis, K., Schneider, L., Patra, U., Schunck, K., Rohleder, E., Hofstetter, J., Baluapuri, A., Scherger, A.K., Slotta-Huspenina, J., Hettler, F., Weber, J., Engleitner, T., Maresch, R., Slawska, J., Lewis, R., Istvanffy, R., Habringer, S., Steiger, K., Baiker, A., Oostendorp, R.A.J., Miething, C., Lenhof, H.P., Bassermann, F., Chapuy, B., Wirth, M., Wolf, E., Rad, R., Müller, S. and Keller, U.
Nature Communications 13
(1): 281.
12 January 2022
Characterization of FarR as a highly specialized, growth phase-dependent transcriptional regulator in Neisseria meningitidis.
Schielke, S., Spatz, C., Schwarz, R.F., Joseph, B., Schoen, C., Schulz, S.M., Hubert, K., Frosch, M., Schubert-Unkmeir, A. and Kurzai, O.
International Journal of Medical Microbiology 301
(4): 325-333.
April 2011
Prognostic impact of Thomsen-Friedenreich tumor antigen and disseminated tumor cells in the bone marrow of breast cancer patients.
Schindlbeck, C., Jeschke, U., Schulze, S., Karsten, U., Janni, W., Rack, B., Krajewski, S., Sommer, H. and Friese, K.
Breast Cancer Research and Treatment 101
(1): 17-25.
January 2007
Characterisation of disseminated tumor cells in the bone marrow of breast cancer patients by the Thomsen-Friedenreich tumor antigen.
Schindlbeck, C., Jeschke, U., Schulze, S., Karsten, U., Janni, W., Rack, B., Sommer, H. and Friese, K.
Histochemistry and Cell Biology 123
(6): 631-637.
1 January 2005
Immunomagnetic enrichment of disseminated tumor cells in bone marrow and blood of breast cancer patients by the Thomsen-Friedenreich-Antigen.
Schindlbeck, C., Stellwagen, J., Jeschke, U., Karsten, U., Rack, B., Janni, W., Jueckstock, J., Tulusan, A., Sommer, H. and Friese, K.
Clinical and Experimental Metastasis 25
(3): 233-240.
May 2008
Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60.
Schirling, C., Heseding, C., Heise, F., Kesper, D., Klebes, A., Klein-Hitpass, L., Vortkamp, A., Hoffmann, D., Saumweber, H. and Ehrenhofer-Murray, A.E.
Chromosoma 119
(1): 99-113.
February 2010
Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity.
Schirmer, D., Grünewald, T.G.P., Klar, R., Schmidt, O., Wohlleber, D., Rubio, R.A., Uckert, W., Thiel, U., Bohne, F., Busch, D.H., Krackhardt, A.M., Burdach, S. and Richter, G.H.S.
OncoImmunology 5
(6): e1175795.
25 April 2016
Hans Gummel anlaesslich seines 30. Todesjahres. 1954-1973 Leitender Chirurg und Direktor der Robert-Roessle-Klinik [Hans Gummel on the 30th anniversary of his death. 1954-1973 chief surgeon and director of the Robert-Rossle Clinic].
Schlag, P.M.
Chirurg 75
(3): 300-301.
1 March 2004
Aspekte chirurgischer Therapie des kolorektalen Karzinoms.
Schlag, P.M.
Praxis : Schweizerische Rundschau fuer Medizin 91
(43): 1806-1810.
23 October 2002
Sentinel-Lymphknoten-Biopsie bei Tumoren des Gastrointestinaltrakts.
Schlag, P.M., Bembenek, A., Bayraktar, S., Gretschel, S., Ulmer, C., Huenerbein, M. and Moesta, K.T.
Onkologe 9
(6): 625-631.
1 January 2003
Sentinel lymph node biopsy (SLNB) in GI-tract cancer.
Schlag, P.M., Bembenek, A., Gretschel, S. and Rau, B.
Tumori 1
: S22-S23.
2002
Bildgebende Verfahren in der Primaer- und Rezidivdiagnostik [Imaging procedures for primary and recurrent diagnostics].
Schlag, P.M., Dresel, S. and Gebauer, B.
Onkologe 15
(5): 487-495.
May 2009
Aspekte operativer Therapie gastrointestinaler Karzinome beim alten Patienten.
Schlag, P.M., Gretschel, S., Moesta, T., Ulmer, C., Benhidjeb, T. and Slisow, W.
Onkologe 8
(2): 167-172.
February 2002
Operative Interdisziplinaritaet und Telematik [Interdisciplinary surgery and telemedicine].
Schlag, P.M., Huenerbein, M., Ulmer, C. and Graschew, G.
Chirurg 75
(4): 411-417.
April 2004
Tumorkonferenz mittels multimedialer Videotelekommunikation.
Schlag, P.M., Ulmer, C. and Graschew, G.
Onkologe 9
(1): 13-22.
January 2003
H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.
Schleich, K., Kase, J., Dörr, J.R., Trescher, S., Bhattacharya, A., Yu, Y., Wailes, E.M., Fan, D.N.Y., Lohneis, P., Milanovic, M., Lau, A., Lenze, D., Hummel, M., Chapuy, B., Leser, U., Reimann, M., Lee, S. and Schmitt, C.A.
Nature Communications 11
(1): 3651.
20 July 2020
Risk-adapted postremission therapy in acute myeloid leukemia: results of the German multicenter AML HD93 treatment trial.
Schlenk, R.F., Benner, A., Hartmann, F., del Valle, F., Weber, C., Pralle, H., Fischer, J.T., Gunzer, U., Pezzutto, A., Weber, W., Grimminger, W., Preiss, J., Hensel, M., Froehling, S., Doehner, K., Haas, R. and Doehner, H.
Leukemia 17
(8): 1521-1528.
1 August 2003
Differential impact of allelic ratio and insertion site in FLT3-ITD–positive AML with respect to allogeneic transplantation.
Schlenk, R.F., Kayser, S., Bullinger, L., Kobbe, G., Casper, J., Ringhoffer, M., Held, G., Brossart, P., Lübbert, M., Salih, H.R., Kindler, T., Horst, H.A., Wulf, G., Nachbaur, D., Götze, K., Lamparter, A., Paschka, P., Gaidzik, V.I., Teleanu, V., Späth, D., Benner, A., Krauter, J., Ganser, A., Döhner, H. and Döhner, K.
Blood 124
(23): 3441-3449.
27 November 2014
The value of allogeneic and autologous hematopoietic stem cell transplantation in prognostically favorable acute myeloid leukemia with double mutant CEBPA.
Schlenk, R.F., Taskesen, E., van Norden, Y., Krauter, J., Ganser, A., Bullinger, L., Gaidzik, V.I., Paschka, P., Corbacioglu, A., Göhring, G., Kündgen, A., Held, G., Götze, K., Vellenga, E., Kuball, J., Schanz, U., Passweg, J., Pabst, T., Maertens, J., Ossenkoppele, G.J., Delwel, R., Döhner, H., Cornelissen, J.J., Döhner, K. and Löwenberg, B.
Blood 122
(9): 1576-1582.
29 August 2013
Chimeric PD-1:28 receptor upgrades low-avidity T cells and restores effector function of tumor-infiltrating lymphocytes for adoptive cell therapy.
Schlenker, R., Olguín-Contreras, L.F., Leisegang, M., Schnappinger, J., Disovic, A., Rühland, S., Nelson, P.J., Leonhardt, H., Harz, H., Wilde, S., Schendel, D.J., Uckert, W., Willimsky, G. and Noessner, E.
Cancer Research 77
(13): 3577-3590.
1 July 2017
Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct.
Schlereth, B., Fichtner, I., Lorenczewski, G., Kleindienst, P., Brischwein, K., da Silva, A., Kufer, P., Lutterbuese, R., Junghahn, I., Kasimir-Bauer, S., Wimberger, P., Kimmig, R. and Baeuerle, P.A.
Cancer Research 65
: 2882-2889.
1 January 2005
Potent inhibition of local and disseminated tumor growth in immunocompetent mouse models by a bispecific antibody construct specific for Murine CD3.
Schlereth, B., Kleindienst, P., Fichtner, I., Lorenczewski, G., Brischwein, K., Lippold, S., Silva, A.D., Locher, M., Kischel, R., Lutterbuese, R., Kufer, P. and Baeuerle, P.A.
Cancer Immunology Immunotherapy 55
: 785-796.
July 2006
T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct.
Schlereth, B., Quadt, C., Dreier, T., Kufer, P., Lorenczewski, G., Prang, N., Brandl, C., Lippold, S., Cobb, K., Brasky, K., Leo, E., Bargou, R., Murthy, K. and Baeuerle, P.A.
Cancer Immunology Immunotherapy 55
: 503-514.
May 2006
The inhibition of the integrin VLA-4 in MV3 melanoma cell binding by non-anticoagulant heparin derivatives.
Schlesinger, M., Schmitz, P., Zeisig, R., Naggi, A., Torri, G., Casu, B. and Bendas, G.
Thrombosis Research 129
(5): 603-610.
May 2012
Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N., Cauchy, P., Franke, V., Giefing, M., Fornes, O., Vankadari, N., Assi, S.A., Costanza, M., Weniger, M.A., Akalin, A., Anagnostopoulos, I., Bukur, T., Casarotto, M.G., Damm, F., Daumke, O., Edginton-White, B., Gebhardt, J.C.M., Grau, M., Grunwald, S., Hansmann, M.L., Hartmann, S., Huber, L., Kärgel, E., Lusatis, S., Noerenberg, D., Obier, N., Pannicke, U., Fischer, A., Reisser, A., Rosenwald, A., Schwarz, K., Sundararaj, S., Weilemann, A., Winkler, W., Xu, W., Lenz, G., Rajewsky, K., Wasserman, W.W., Cockerill, P.N., Scheidereit, C., Siebert, R., Küppers, R., Grosschedl, R., Janz, M., Bonifer, C. and Mathas, S.
Nature Communications 14
(1): 6947.
7 November 2023
The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Schleussner, N., Merkel, O., Costanza, M., Liang, H.C., Hummel, F., Romagnani, C., Durek, P., Anagnostopoulos, I., Hummel, M., Jöhrens, K., Niedobitek, A., Griffin, P.R., Piva, R., Sczakiel, H.L., Woessmann, W., Damm-Welk, C., Hinze, C., Stoiber, D., Gillissen, B., Turner, S.D., Kaergel, E., von Hoff, L., Grau, M., Lenz, G., Dörken, B., Scheidereit, C., Kenner, L., Janz, M. and Mathas, S.
Leukemia 32
(9): 1994-2007.
September 2018
Netboost: boosting-supported network analysis improves high-dimensional omics prediction in acute myeloid leukemia and Huntington's disease.
Schlosser, P., Knaus, J., Schmutz, M., Döhner, K., Plass, C., Bullinger, L., Claus, R., Binder, H., Lübbert, M. and Schumacher, M.
IEEE/ACM Transactions on Computational Biology and Bioinformatics 18
(6): 2635-2648.
1 November 2021
Peptide linkage to the α-subunit of MHCII creates a stably inverted antigen presentation complex.
Schlundt, A., Guenther, S., Sticht, J., Wieczorek, M., Roske, Y., Heinemann, U. and Freund, C.
Journal of Molecular Biology 423
(3): 294-302.
26 October 2012
A xenon-129 biosensor for monitoring MHC-peptide interactions.
Schlundt, A., Kilian, W., Beyermann, M., Sticht, J., Guenther, S., Hoepner, S., Falk, K., Roetzschke, O., Mitschang, L. and Freund, C.
Angewandte Chemie International Edition 48
(23): 4142-4145.
25 May 2009
Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Schmalbrock, L.K., Dolnik, A., Cocciardi, S., Sträng, E., Theis, F., Jahn, N., Panina, E., Blätte, T.J., Herzig, J.K., Skambraks, S., Rücker, F.G., Gaidzik, V.I., Paschka, P., Fiedler, W., Salih, H.R., Wulf, G.G., Schroeder, T., Lübbert, M., Schlenk, R.F., Thol, F., Heuser, M., Larson, R.A., Ganser, A., Stunnenberg, H.G., Minucci, S., Stone, R.M., Bloomfield, C.D., Döhner, H., Döhner, K. and Bullinger, L.
Blood 137
(22): 3093-3104.
3 June 2021
Capillary gel electrophoresis (CGE) for quality control of plasmid DNA in gene therapy: quality control of 20 years stored GMP-grade plasmid DNA.
Schmeer, M., Schleef, M., Shankar, R., Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521
(3): 317-328.
23 June 2022
Induction of gene expression by 5-Aza-2'-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and -independent mechanisms.
Schmelz, K., Sattler, N., Wagner, M., Luebbert, M., Doerken, B. and Tamm, I.
Leukemia 19
: 103-111.
1 January 2005
5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.
Schmelz, K., Wagner, M., Doerken, B. and Tamm, I.
International Journal of Cancer 114
: 683-695.
1 May 2005
Tumor necrosis factor α sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-κB.
Schmelz, K., Wieder, T., Tamm, I., Mueller, A., Essmann, F., Geilen, C.C., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 23
(40): 6743-6759.
2 September 2004
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Schmelz, K., Toedling, J., Huska, M., Cwikla, M.C., Kruetzfeldt, L.M., Proba, J., Ambros, P.F., Ambros, I.M., Boral, S., Lodrini, M., Chen, C.Y., Burkert, M., Guergen, D., Szymansky, A., Astrahantseff, K., Kuenkele, A., Haase, K., Fischer, M., Deubzer, H.E., Hertwig, F., Hundsdoerfer, P., Henssen, A.G., Schwarz, R.F., Schulte, J.H. and Eggert, A.
Nature Communications 12
(1): 6804.
23 November 2021
Sex differences in the drug therapy for oncologic diseases.
Schmetzer, O. and Floercken, A.
Handbook of Experimental Pharmacology 214
(3): 411-442.
2012
Detection of circulating tumor-associated antigen depends on the domains recognized by the monoclonal antibodies used: N-terminal trimmed EpCAM-levels are much higher than untrimmed forms.
Schmetzer, O., Moldenhauer, G., Nicolaou, A., Schlag, P., Riesenberg, R. and Pezzutto, A.
Immunology Letters 143
(2): 184-192.
30 April 2012
Albumin-Binding Prodrugs of Camptothecin and Doxorubicin with an Ala-Leu-Ala-Leu-Linker That Are Cleaved by Cathepsin B: Synthesis and Antitumor Efficacy.
Schmid, B., Chung, D.E., Warnecke, A., Fichtner, I. and Kratz, F.
Bioconjugate Chemistry 18
(3): 702-716.
May 2007
Development of albumin-binding camptothecin prodrugs using a peptide positional scanning library.
Schmid, B., Warnecke, A., Fichtner, I., Jung, M. and Kratz, F.
Bioconjugate Chemistry 18
(6): 1786-1799.
November 2007
SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer.
Schmid, F., Burock, S., Klockmeier, K., Schlag, P.M. and Stein, U.
Molecular Cancer 11
(1): 49.
29 July 2012
SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.
Schmid, F., Wang, Q., Huska, M.R., Andrade-Navarro, M.A., Lemm, M., Fichtner, I., Dahlmann, M., Kobelt, D., Walther, W., Smith, J., Schlag, P.M. and Stein, U.
Oncogene 35
(46): 5942-5952.
17 November 2016
Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker.
Schmid, F., Dahlmann, M., Röhrich, H., Kobelt, D., Hoffmann, J., Burock, S., Walther, W. and Stein, U.
British Journal of Cancer 127
(4): 675-685.
1 September 2022
GiANT: gene set uncertainty in enrichment analysis.
Schmid, F., Schmid, M., Müssel, C., Sträng, J.E., Buske, C., Bullinger, L., Kraus, J.M. and Kestler, H.A.
Bioinformatics 32
(12): 1891-1894.
15 June 2016
B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
Schmid, V.K., Khadour, A., Ahmed, N., Brandl, C., Nitschke, L., Rajewsky, K., Jumaa, H. and Hobeika, E.
Haematologica 107
(8): 1796-1814.
August 2022
Use of Kaede fusions to visualize recycling of G protein-coupled receptors.
Schmidt, A., Wiesner, B., Weisshart, K., Schulz, K., Furkert, J., Lamprecht, B., Rosenthal, W. and Schuelein, R.
Traffic 10
(1): 2-15.
January 2009
Detection of cell-free nucleic acids in bronchial lavage fluid supernatants from patients with lung cancer.
Schmidt, B., Carstensen, T., Engel, E., Jandrig, B., Witt, C. and Fleischhacker, M.
European Journal of Cancer 40
(3): 452-460.
February 2004
Nucleocapsid protein of cell culture-adapted Seoul virus strain 80-39: Analysis of its encoding sequence, expression in yeast and immuno-reactivity.
Schmidt, J., Jandrig, B., Klempa, B., Yoshimatsu, K., Arikawa, J., Meisel, H., Niedrig, M., Pitra, C., Krueger, D.H. and Ulrich, R.
Virus Genes 30
(1): 37-48.
1 January 2005
Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
Schmidt, K., Zilio, S., Schmollinger, J.C., Bronte, V., Blankenstein, T. and Willimsky, G.
Blood 121
(10): 1740-1748.
7 March 2013
Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt, F., Gasparoni, N., Gasparoni, G., Gianmoena, K., Cadenas, C., Polansky, J.K., Ebert, P., Nordstroem, K., Barann, M., Sinha, A., Froehler, S., Xiong, J., Dehghani Amirabad, A., Behjati Ardakani, F., Hutter, B., Zipprich, G., Felder, B., Eils, J., Brors, B., Chen, W., Hengstler, J.G., Hamann, A., Lengauer, T., Rosenstiel, P., Walter, J. and Schulz, M.H.
Nucleic Acids Research 45
(1): 54-66.
9 January 2017
Regulation of the natriuretic peptide receptor 2 (Npr2) by phosphorylation of juxtamembrane serine and threonine residues is essential for bifurcation of sensory axons.
Schmidt, H., Dickey, D.M., Dumoulin, A., Octave, M., Robinson, J.W., Kühn, R., Feil, R., Potter, L.R. and Rathjen, F.G.
Journal of Neuroscience 38
(45): 9768-9780.
7 November 2018
ERAP1-dependent antigen cross-presentation determines efficacy of adoptive T cell therapy in mice.
Schmidt, K., Keller, C., Kühl, A.A., Textor, A., Seifert, U., Blankenstein, T., Willimsky, G. and Kloetzel, P.M.
Cancer Research 78
(12): 3243-3254.
June 2018
B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS.
Schmidt, K., Sack, U., Graf, R., Winkler, W., Popp, O., Mertins, P., Sommermann, T., Kocks, C. and Rajewsky, K.
Frontiers in Immunology 11
: 602868.
1 December 2020
Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis.
Schmidt, O., Nehls, N., Prexler, C., von Heyking, K., Groll, T., Pardon, K., Garcia, H.D., Hensel, T., Gürgen, D., Henssen, A.G., Eggert, A., Steiger, K., Burdach, S. and Richter, G.H.S.
Journal of Experimental & Clinical Cancer Research 40
(1): 322.
15 October 2021
NF-kappaB activity in transgenic mice: developmental regulation and tissue specificity.
Schmidt-Ullrich, R., Memet, S., Lilienbaum, A., Feuillard, J., Raphael, M. and Israel, A.
Development 122
(7): 2117-2128.
July 1996
NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.
Schmidt-Ullrich, R., Tobin, D.J., Lenhard, D., Schneider, P., Paus, R. and Scheidereit, C.
Development 133
(6): 1045-1057.
15 March 2006
TFE3 activation in a TSC1-altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms.
Schmiester, M., Dolnik, A., Kornak, U., Pfitzner, B., Hummel, M., Treue, D., Hartmann, A., Agaimy, A., Weyerer, V., Lekaj, A., Brakemeier, S., Peters, R., Öllinger, R., Märdian, S., Bullinger, L., Striefler, J.K. and Flörcken, A.
Journal of Pathology Clinical Research 7
(1): 3-9.
January 2021
Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
Schmiester, M., Maier, R., Riedel, R., Durek, P., Frentsch, M., Kolling, S., Mashreghi, M.F., Jenq, R., Zhang, L., Peterson, C.B., Bullinger, L., Chang, H.D. and Na, I.K.
Gut Microbes 14
(1): e2081475.
29 May 2022
Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.
Schmiester, M., Tranter, E., Lorusso, A., Blaschke, F., Geisel, D., Bullinger, L., Damm, F. and Na, I.K.
BMC Cardiovascular Disorders 22
(1): 31.
4 February 2022
COVID-19 and cellular senescence.
Schmitt, C.A., Tchkonia, T., Niedernhofer, L.J., Robbins, P.D., Kirkland, J.L. and Lee, S.
Nature Reviews Immunology 23
(4): 251-263.
April 2023
Phenotypic mapping of pathologic cross-talk between glioblastoma and innate immune cells by synthetic genetic tracing.
Schmitt, M.J., Company, C., Dramaretska, Y., Barozzi, I., Göhrig, A., Kertalli, S., Großmann, M., Naumann, H., Sánchez-Bailón, M.P., Hulsman, D., Glass, R., Squatrito, M., Serresi, M. and Gargiulo, G.
Cancer Discovery 11
(3): 754-777.
March 2021
Four versus six courses of a dose-escalated cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) regimen plus etoposide (megaCHOEP) and autologous stem cell transplantation.
Schmitz, N., Kloess, M., Reiser, M., Berdel, W.E., Metzner, B., Doerken, B., Kneba, M., Trumper, L., Loeffler, M., Pfreundschuh, M. and Glass, B.
Cancer 106
: 136-145.
1 January 2006
A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first-line therapy in poor-risk peripheral T-NHL.
Schmitz, N., Truemper, L.H., Bouabdallah, K., Ziepert, M., Leclerc, M., Cartron, G., Jaccard, A., Reimer, P., Wagner-Drouet, E.M., Wilhelm, M., Sanhes, L., Lamy, T., de Leval, L., Rosenwald, A., Roussel, M., Kroschinsky, F.P., Lindemann, W.W., Dreger, P., Viardot, A., Milpied, N.J., Gisselbrecht, C., Wulf, G.G., Gyan, E., Gaulard, P., Bay, J.O., Glass, B., Poeschel, V., Damaj, G., Sibon, D., Delmer, A.J., Bilger, K., Banos, A., Haenel, M., Dreyling, M., Metzner, B., Keller, U., Braulke, F., Friedrichs, B., Nickelsen, M., Altmann, B. and Tournilhac, O.
Blood 137
(19): 2646-2656.
13 May 2021
Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen.
Schmutz, M., Zucknick, M., Schlenk, R.F., Mertens, D., Benner, A., Weichenhan, D., Mücke, O., Döhner, K., Plass, C., Bullinger, L. and Claus, R.
Clinical Epigenetics 15
(1): 171.
26 October 2023
Overexpression of sialyltransferase CMP-sialic Acid : Galbeta1,3GalNAc-R alpha6-sialyltransferase is related to poor patient survival in human colorectal carcinomas.
Schneider, F., Kemmner, W., Haensch, W., Franke, G., Gretschel, S., Karsten, U. and Schlag, P.M.
Cancer Research 61
(11): 4605-4611.
1 June 2001
CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells.
Schneider, M.A., Meingassner, J.G., Lipp, M., Moore, H.D. and Rot, A.
Journal of Experimental Medicine 204
(4): 735-745.
16 April 2007
Micro-ribonucleic acid-155 is a direct target of Meis1, but not a driver in acute myeloid leukemia.
Schneider, E., Staffas, A., Röhner, L., Malmberg, E.D., Ashouri, A., Krowiorz, K., Pochert, N., Miller, C., Wei, S.Y., Arabanian, L., Buske, C., Döhner, H., Bullinger, L., Fogelstrand, L., Heuser, M., Döhner, K., Xiang, P., Ruschmann, J., Petriv, O.I., Heravi-Moussavi, A., Hansen, C.L., Hirst, M., Humphries, R.K., Rouhi, A., Palmqvist, L. and Kuchenbauer, F.
Haematologica 103
(2): 246-255.
February 2018
Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J., Sundaravinayagam, D., Blume, A., Marg, A., Grunwald, S., Metzler, E., Escobar, H., Müthel, S., Wang, H., Wollersheim, T., Weber-Carstens, S., Akalin, A., Di Virgilio, M., Tursun, B. and Spuler, S.
International Journal of Molecular Sciences 24
(3): 2772.
1 February 2023
Flow cytometric maturity score as a novel prognostic parameter in patients with acute myeloid leukemia.
Schneider, T., Flörcken, A., Singh, A., Türkmen, S., Burmeister, T., Anagnostopoulos, I., Pezzutto, A., Dörken, B. and Westermann, J.
Annals of Hematology 94
(8): 1337-1345.
August 2015
Leukemic stem cells of acute myeloid leukemia patients carrying NPM1 mutation are candidates for targeted immunotherapy.
Schneider, V., Zhang, L., Bullinger, L., Rojewski, M., Hofmann, S., Wiesneth, M., Schrezenmeier, H., Götz, M., Botzenhardt, U., Barth, T.F.E., Döhner, K., Döhner, H. and Greiner, J.
Leukemia 28
(8): 1759-62.
August 2014
Leukemic progenitor cells are susceptible to targeting by stimulated cytotoxic T cells against immunogenic leukemia-associated antigens.
Schneider, V., Zhang, L., Rojewski, M., Fekete, N., Schrezenmeier, H., Erle, A., Bullinger, L., Hofmann, S., Götz, M., Döhner, K., Ihme, S., Döhner, H., Buske, C., Feuring-Buske, M. and Greiner, J.
International Journal of Cancer 137
(9): 2083-2092.
1 November 2015
Operative Therapie des malignen Melanoms [Operative treatment of malignant melanomas].
Schneider-Burrus, S., Drecoll, U. and Schlag, P.M.
Onkologe 15
(8): 750-757.
August 2009
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M., Schwarzer, A., Jayavelu, A.K., Hsu, C.J., Kirkpatrick, J., Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S.A., Nafria, M., Jiang, L., Dai, Y.T., Chen, Z., Chen, S.J., Kellaway, S.G., Ptasinska, A., Ng, E.S., Stanley, E.G., Elefanty, A.G., Buschbeck, M., Bierhoff, H., Brodt, S., Matziolis, G., Fischer, K.D., Hochhaus, A., Chen, C.W., Heidenreich, O., Mann, M., Lane, S.W., Bullinger, L., Ori, A., von Eyss, B., Bonifer, C. and Heidel, F.
Blood 139
(7): 1080-1097.
17 February 2022
Epo-induced erythroid maturation is dependent on Plcγ1 signaling.
Schnöder, T.M., Arreba-Tutusaus, P., Griehl, I., Bullinger, L., Buschbeck, M., Lane, S.W., Döhner, K., Plass, C., Lipka, D.B., Heidel, F.H. and Fischer, T.
Cell Death and Differentiation 22
(6): 974-985.
June 2015
TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells.
Schoeler, K., Aufschnaiter, A., Messner, S., Derudder, E., Herzog, S., Villunger, A., Rajewsky, K. and Labi, V.
FEBS Journal 286
(18): 3566-3581.
September 2019
Development of a BAC vector for integration-independent and tight regulation of transgenes in rodents via the Tet system.
Schoenig, K., Kentner, D., Gossen, M., Baldinger, T., Miao, J., Welzel, K., Vente, A., Bartsch, D. and Bujard, H.
Transgenic Research 20
(3): 709-720.
June 2011
Reciprocal regulation of glycine-rich RNA-binding proteins via an interlocked feedback loop coupling alternative splicing to nonsense-mediated decay in Arabidopsis.
Schoening, J.C., Streitner, C., Meyer, I.M., Gao, Y. and Staiger, D.
Nucleic Acids Research 36
(22): 6977-6987.
December 2008
Dysferlin-peptides reallocate mutated dysferlin thereby restoring function.
Schoewel, V., Marg, A., Kunz, S., Overkamp, T., Siegert Carrazedo, R., Zacharias, U., Daniel, P.T. and Spuler, S.
PLoS ONE 7
(11): e49603.
20 November 2012
Activation of human T cell lymphotropic virus type I-infected T cells is independent of B7 costimulation.
Scholz, C., Freeman, G.J., Greenfield, E.A., Hafler, D.A. and Hollsberg, P.
Journal of Immunology 157
(7): 2932-2938.
1 October 1996
Distinction of acute lymphoblastic leukemia from acute myeloid leukemia through microarray-based DNA methylation analysis.
Scholz, C., Nimmrich, I., Burger, M., Becker, E., Doerken, B., Ludwig, W.D. and Maier, S.
Annals of Hematology 84
: 236-244.
1 January 2005
Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway.
Scholz, C., Richter, A., Lehmann, M., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 24
(47): 7031-7042.
27 October 2005
Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.
Scholz, C., Wieder, T., Staerck, L., Essmann, F., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 24
: 1904-1913.
1 January 2005
(90)Yttrium-ibritumomab-tiuxetan as first-line treatment for follicular lymphoma: 30 months of follow-up data from an international multicenter phase II clinical trial.
Scholz, C.W., Pinto, A., Linkesch, W., Lindén, O., Viardot, A., Keller, U., Hess, G., Lastoria, S., Lerch, K., Frigeri, F., Arcamone, M., Stroux, A., Frericks, B., Pott, C. and Pezzutto, A.
Journal of Clinical Oncology 31
(3): 308-313.
20 January 2013
The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Scholz, F., Grau, M., Menzel, L., Graband, A., Zapukhlyak, M., Leutz, A., Janz, M., Lenz, G., Rehm, A. and Höpken, U.E.
Proceedings of the National Academy of Sciences of the United States of America 117
(42): 26328-26339.
20 October 2020
High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA): a single-arm, phase 2 trial.
Schorb, E., Isbell, L.K., Kerkhoff, A., Mathas, S., Braulke, F., Egerer, G., Röth, A., Schliffke, S., Borchmann, P., Brunnberg, U., Kroschinsky, F., Möhle, R., Rank, A., Wellnitz, D., Kasenda, B., Pospiech, L., Wendler, J., Scherer, F., Deckert, M., Henkes, E., von Gottberg, P., Gmehlin, D., Backenstraß, M., Jensch, A., Burger-Martin, E., Grishina, O., Fricker, H., Malenica, N., Orbán, A., Duyster, J., Ihorst, G., Finke, J. and Illerhaus, G.
Lancet Haematology 11
(3): e196-e205.
March 2024
Downregulation of genes involved in DNA repair and differential expression of transcription regulators and phosphatases precede IgM-induced apoptosis in the Burkitt's lymphoma cell line BL60-2.
Schories, B., Janz, M., Doerken, B. and Bommert, K.
Biochimica et Biophysica Acta - Gene Structure and Expression 1676
(1): 83-95.
1 January 2004
Target selection for T-cell therapy in epithelial ovarian cancer: systematic prioritization of self-antigens.
Schossig, P., Coskun, E., Arsenic, R., Horst, D., Sehouli, J., Bergmann, E., Andresen, N., Sigler, C., Busse, A., Keller, U. and Ochsenreither, S.
International Journal of Molecular Sciences 24
(3): 2292.
24 January 2023
An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
Schrade, K., Tröger, J., Eldahshan, A., Zühlke, K., Abdul Azeez, K.R., Elkins, J.M., Neuenschwander, M., Oder, A., Elkewedi, M.M.H., Jaksch, S., Andrae, K., Li, J., Fernandes, J., Müller, P.M., Grunwald, S., Marino, S.F., Vukićević, T., Eichhorst, J., Wiesner, B., Weber, M., Kapiloff, M., Rocks, O., Daumke, O., Wieland, T., Knapp, S., von Kries, J.P. and Klussmann, E.
PLoS ONE 13
(1): e0191423.
26 January 2018
Mutational dynamics between primary and relapse neuroblastomas.
Schramm, A., Köster, J., Assenov, Y., Althoff, K., Peifer, M., Mahlow, E., Odersky, A., Beisser, D., Ernst, C., Henssen, A.G., Stephan, H., Schröder, C., Heukamp, L., Engesser, A., Kahlert, Y., Theissen, J., Hero, B., Roels, F., Altmüller, J., Nürnberg, P., Astrahantseff, K., Gloeckner, C., De Preter, K., Plass, C., Lee, S., Lode, H.N., Henrich, K.O., Gartlgruber, M., Speleman, F., Schmezer, P., Westermann, F., Rahmann, S., Fischer, M., Eggert, A. and Schulte, J.H.
Nature Genetics 47
(8): 872-877.
August 2015
Automated two-dimensional spatiotemporal analysis of mobile single-molecule FRET probes.
Schrangl, L., Göhring, J., Kellner, F., Huppa, J.B. and Schütz, G.J.
Journal of Visualized Experiments 177
: e63124.
23 November 2021
Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis.
Schreiber, T., Ehlers, S., Aly, S., Hoelscher, A., Hartmann, S., Lipp, M., Lowe, J.B. and Hoelscher, C.
Journal of Immunology 176
(2): 1131-1140.
15 January 2006
Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures.
Schroeder, M.P., Bastian, L., Eckert, C., Gökbuget, N., James, A.R., Ortiz Tanchez, J., Schlee, C., Isaakidis, K., Häupl, B., Baum, K., Migueles Lozano, O.A., Kouidri, K., Pan, K.T., Urlaub, H., Schwartz, S., Burmeister, T., von Stackelberg, A., Hoelzer, D., Pfeiffer, H., Rieger, M.A., Göllner, S., Oellerich, T., Horstman, M., Schrappe, M., Wolf, J., Kirschner-Schwabe, R., Brüggemann, M., Müller-Tidow, C., Serve, H., Neumann, M. and Baldus, C.D.
Scientific Reports 9
(1): 4188.
12 March 2019
Treatment of adult ALL patients with third-generation CD19-directed CAR T cells: results of a pivotal trial.
Schubert, M.L., Schmitt, A., Hückelhoven-Krauss, A., Neuber, B., Kunz, A., Waldhoff, P., Vonficht, D., Yousefian, S., Jopp-Saile, L., Wang, L., Korell, F., Keib, A., Michels, B., Haas, D., Sauer, T., Derigs, P., Kulozik, A., Kunz, J., Pavel, P., Laier, S., Wuchter, P., Schmier, J., Bug, G., Lang, F., Gökbuget, N., Casper, J., Görner, M., Finke, J., Neubauer, A., Ringhoffer, M., Wolleschak, D., Brüggemann, M., Haas, S., Ho, A.D., Müller-Tidow, C., Dreger, P. and Schmitt, M.
Journal of Hematology & Oncology 16
(1): 79.
22 July 2023
Cutting edge: CD8+ effector T cells reject tumors by direct antigen recognition but indirect action on host cells.
Schueler, T. and Blankenstein, T.
Journal of Immunology 170
(9): 4427-4431.
1 May 2003
Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8+ T cells.
Schueler, T., Kammertoens, T., Preiss, S., Debs, P., Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 194
(12): 1767-1775.
17 December 2001
Tumor rejection by modulation of tumor stromal fibroblasts.
Schueler, T., Koernig, S. and Blankenstein, T.
Journal of Experimental Medicine 198
(10): 1487-1493.
17 November 2003
T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice.
Schueler, T., Qin, Z., Ibe, S., Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 189
(5): 803-810.
1 March 1999
Moessbauer- and EPR-snapshots of an enzymatic reaction: The cytochrome P450 reaction cycle.
Schuenemann, V., Jung, C., Lendzian, F., Barra, A.L., Teschner, T. and Trautwein, A.X.
Hyperfine Interactions 156
(1-4): 247-256.
1 January 2004
Tyrosine radical formation in the reaction of wild type and mutant cytochrome P450cam with peroxy acids: A multifrequency EPR study of intermediates on the millisecond time scale.
Schuenemann, V., Lendzian, F., Jung, C., Contzen, J., Barra, A.L., Sligar, S.G. and Trautwein, A.X.
Journal of Biological Chemistry 279
(12): 10919-10930.
19 March 2004
Non-leucine residues in the leucine repeats of Fos and Jun contribute to the stability and determine the specificity of dimerization.
Schuermann, M., Hunter, J.B., Hennig, M. and Mueller, R.
Nucleic Acids Research 19
(4): 739-746.
25 February 1991
Roquin binding to target mRNAs involves a winged helix-turn-helix motif.
Schuetz, A., Murakawa, Y., Rosenbaum, E., Landthaler, M. and Heinemann, U.
Nature Communications 5
: 5701.
11 December 2014
The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation.
Schuetz, A., Nana, D., Rose, C., Zocher, G., Milanovic, M., Koenigsmann, J., Blasig, R., Heinemann, U. and Carstanjen, D.
Cellular and Molecular Life Sciences 68
(18): 3121-3131.
September 2011
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
Schuetz, G., Rosario, M., Grimm, J., Boeckers, T.M., Gundelfinger, E.D. and Birchmeier, W.
Journal of Cell Biology 167
(5): 945-952.
6 December 2004
Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Schuetz, A., Radusheva, V., Krug, S.M. and Heinemann, U.
Annals of the New York Academy of Sciences 1405
(1): 147-159.
October 2017
Neoadjuvant chemotherapy compared with surgery alone for locally advanced cancer of the stomach and cardia: European Organisation for Research and Treatment of Cancer Randomized Trial 40954.
Schuhmacher, C., Gretschel, S., Lordick, F., Reichardt, P., Hohenberger, W., Eisenberger, C.F., Haag, C., Mauer, M.E., Hasan, B., Welch, J., Ott, K., Hoelscher, A., Schneider, P.M., Bechstein, W., Wilke, H., Lutz, M.P., Nordlinger, B., Van Cutsem, E., Siewert, J.R. and Schlag, P.M.
Journal of Clinical Oncology 28
(35): 5210-5218.
10 December 2010
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.
Schuijers, J., Junker, J.P., Mokry, M., Hatzis, P., Koo, B.K., Sasselli, V., van der Flier, L.G., Cuppen, E., van Oudenaarden, A. and Clevers, H.
Cell Stem Cell 16
(2): 158-170.
5 February 2015
Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells.
Schulte, J.H., Kirfel, J., Lim, S., Schramm, A., Friedrichs, N., Deubzer, H.E., Witt, O., Eggert, A. and Buettner, R.
Cancer Letters 271
(1): 56-63.
18 November 2008
The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion.
Schulte, K., Pawlowski, N., Faelber, K., Fröhlich, C., Howard, J. and Daumke, O.
BMC Biology 14
(1): 14.
2 March 2016
Structural basis for aryl hydrocarbon receptor-mediated gene activation.
Schulte, K.W., Green, E., Wilz, A., Platten, M. and Daumke, O.
Structure 25
(7): 1025-1033.
5 July 2017
Severe COVID-19 is marked by a dysregulated myeloid cell compartment.
Schulte-Schrepping, J., Reusch, N., Paclik, D., Baßler, K., Schlickeiser, S., Zhang, B., Krämer, B., Krammer, T., Brumhard, S., Bonaguro, L., De Domenico, E., Wendisch, Da., Grasshoff, M., Kapellos, T.S., Beckstette, M., Pecht, T., Saglam, A., Dietrich, O., Mei, H.E., Schulz, A.R., Conrad, C., Kunkel, D., Vafadarnejad, E., Xu, C.J., Horne, A., Herbert, M., Drews, A., Thibeault, C., Pfeiffer, M., Hippenstiel, S., Hocke, A., Müller-Redetzky, H., Heim, K.M., Machleidt, F., Uhrig, A., Bosquillon de Jarcy, L., Jürgens, L., Stegemann, M., Glösenkamp, C.R., Volk, H.D., Goffinet, C., Landthaler, M., Wyler, E., Georg, P., Schneider, M., Dang-Heine, C., Neuwinger, N., Kappert, K., Tauber, R., Corman, V., Raabe, J., Kaiser, K.M., Vinh, M.T., Rieke, G., Meisel, C., Ulas, T., Becker, M., Geffers, R., Witzenrath, M., Drosten, C., Suttorp, N., von Kalle, C., Kurth, F., Händler, K., Schultze, J.L., Aschenbrenner, A.C., Li, Y., Nattermann, J., Sawitzki, B., Saliba, A.E. and Sander, L.E.
Cell 182
(6): 1419-1440.
17 September 2020
Activation-dependent TRAF3 exon 8 alternative splicing is controlled by CELF2 and hnRNP C binding to an upstream intronic element.
Schultz, A.S., Preussner, M., Bunse, M., Karni, R. and Heyd, F.
Molecular and Cellular Biology 37
(7): e.00488-16.
April 2017
Role of LDL receptor-related protein (LRP) in coronary atherosclerosis.
Schulz, S., Birkenmeier, G., Schagdarsurengin, U., Wenzel, K., Mueller-Werdan, U., Rehfeld, D., Suess, T., Kabisch, A., Werdan, K. and Glaeser, C.
International Journal of Cardiology 92
(2-3): 137-144.
1 January 2003
Helicobacter pylori - neue Aspekte kommender Leitlinien [Helicobacter pylori - new aspects of forthcoming guidelines].
Schulz, C., Fischbach, W., Sigal, M., Schütte, K., Suerbaum, S. and Malfertheiner, P.
Internist 63
(4): 367-371.
1 March 2022
Loss-of-function uORF mutations in human malignancies.
Schulz, J., Mah, N., Neuenschwander, M., Kischka, T., Ratei, R., Schlag, P.M., Castaños-Vélez, E., Fichtner, I., Tunn, P.U., Denkert, C., Klaas, O., Berdel, W.E., von Kries, J.P., Makalowski, W., Andrade-Navarro, M.A., Leutz, A. and Wethmar, K.
Scientific Reports 8
(1): 2395.
5 February 2018
Structural and functional characterization of human Iba proteins.
Schulze, J.O., Quedenau, C., Roske, Y., Adam, T., Schueler, H., Behlke, J., Turnbull, A.P., Sievert, V., Scheich, C., Mueller, U., Heinemann, U. and Buessow, K.
FEBS Journal 275
(18): 4627-4640.
September 2008
Sphingosine-1-phospate receptor 4 (S1P4) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model.
Schulze, T., Golfier, S., Tabeling, C., Raebel, K., Graeler, M.H., Witzenrath, M. and Lipp, M.
FASEB Journal 25
(11): 4024-4036.
November 2011
Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tumor cells in colorectal cancer patients following resection of liver metastases: results of a prospective randomized trial.
Schulze, T., Kemmner, W., Weitz, J., Wernecke, K.D., Schirrmacher, V. and Schlag, P.M.
Cancer Immunology Immunotherapy 58
(1): 61-69.
January 2009
Long-term morbidity of patients with early breast cancer after sentinel lymph node biopsy compared to axillary lymph node dissection.
Schulze, T., Mucke, J., Markwardt, J., Schlag, P.M. and Bembenek, A.
Journal of Surgical Oncology 93
: 109-119.
1 February 2006
Lipopolysaccharide induces the rapid tyrosine phosphorylation of the mitogen-activated protein kinases erk-1 and p38 in cultured human vascular endothelial cells requiring the presence of soluble CD14.
Schumann, R.R., Pfeil, D., Lamping, N., Kirschning, C., Scherzinger, G., Schlag, P.M., Karawajew, L. and Herrmann, F.
Blood 87
(7): 2805-2814.
1 April 1996
Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells.
Schumann, R.R., Belka, C., Reuter, D., Lamping, N., Kirschning, C., Weber, J.R. and Pfeil, D.
Blood 91
(2): 577-584.
15 January 1998
SigsPack, a package for cancer mutational signatures.
Schumann, F., Blanc, E., Messerschmidt, C., Blankenstein, T., Busse, A. and Beule, D.
BMC Bioinformatics 20
(1): 450.
2 September 2019
CCR7 deficiency causes diarrhea associated with altered ion transport in colonocytes in the absence of overt colitis.
Schumann, M., Winter, S., Wichner, K., May, C., Kuehl, A.A., Batra, A., Siegmund, B., Zeitz, M., Schulzke, J.D., Lipp, M. and Höpken, U.E.
Mucosal Immunology 5
(4): 377-387.
July 2012
The transcriptome dynamics of single cells during the cell cycle.
Schwabe, D., Formichetti, S., Junker, J.P., Falcke, M. and Rajewsky, N.
Molecular Systems Biology 16
(11): e9946.
1 November 2020
Clostridium difficile toxin CDT hijacks microtubule organization and reroutes vesicle traffic to increase pathogen adherence.
Schwan, C., Kruppke, A.S., Nölke, T., Schumacher, L., Koch-Nolte, F., Kudryashev, M., Stahlberg, H. and Aktories, K.
Proceedings of the National Academy of Sciences of the United States of America 111
(6): 2313-2318.
11 February 2014
Global analysis of cellular protein translation by pulsed SILAC.
Schwanhaeusser, B., Gossen, M., Dittmar, G. and Selbach, M.
Proteomics 9
(1): 205-209.
January 2009
The cytomegalovirus M35 protein directly binds to the interferon-β enhancer and modulates transcription of (Ifnb1) and other IRF3-driven genes.
Schwanke, H., Gonçalves Magalhães, V., Schmelz, S., Wyler, E., Hennig, T., Günther, T., Grundhoff, A., Dölken, L., Landthaler, M., van Ham, M., Jänsch, L., Büssow, K., van den Heuvel, J., Blankenfeldt, W., Friedel, C.C., Erhard, F. and Brinkmann, M.M.
Journal of Virology 97
(6): e0040023.
29 June 2023
Spatio-temporal bone remodeling after hematopoietic stem cell transplantation.
Schwarz, C.S., Bucher, C.H., Schlundt, C., Mertlitz, S., Riesner, K., Kalupa, M., Verlaat, L., Schmidt-Bleek, O., Sass, R.A., Schmidt-Bleek, K., Duda, G.N., Penack, O. and Na, I.K.
International Journal of Molecular Sciences 22
(1): 267.
29 December 2020
Evaluation of one- and two-color gene expression arrays for microbial comparative genome hybridization analyses in routine applications.
Schwarz, R., Joseph, B., Gerlach, G., Schramm-Glueck, A., Engelhard, K., Frosch, M., Mueller, T. and Schoen, C.
Journal of Clinical Microbiology 48
(9): 3105-3110.
September 2010
Integrated network reconstruction, visualization and analysis using YANAsquare.
Schwarz, R., Liang, C., Kaleta, C., Kuehnel, M., Hoffmann, E., Kuznetsov, S., Hecker, M., Griffiths, G., Schuster, S. and Dandekar, T.
BMC Bioinformatics 8
: 313.
28 August 2007
YANA - a software tool for analyzing flux modes, gene-expression and enzyme activities.
Schwarz, R., Musch, P., von Kamp, A., Engels, B., Schirmer, H., Schuster, S. and Dandekar, T.
BMC Bioinformatics 6
: 135.
1 June 2005
Detecting species-site dependencies in large multiple sequence alignments.
Schwarz, R., Seibel, P.N., Rahmann, S., Schoen, C., Huenerberg, M., Mueller-Reible, C., Dandekar, T., Karchin, R., Schultz, J. and Mueller, T.
Nucleic Acids Research 37
(18): 5959-5968.
October 2009
A probabilistic model of cell size reduction in Pseudo-nitzschia delicatissima (Bacillariophyta).
Schwarz, R., Wolf, M. and Mueller, T.
Journal of Theoretical Biology 258
(2): 316-322.
21 May 2009
Changes in postural syntax characterize sensory modulation and natural variation of C. elegans locomotion.
Schwarz, R.F., Branicky, R., Grundy, L.J., Schafer, W.R. and Brown, A.E.X.
PLoS Computational Biology 11
(8): e1004322.
21 August 2015
Evolutionary distances in the twilight zone-a rational kernel approach.
Schwarz, R.F., Fletcher, W., Foerster, F., Merget, B., Wolf, M., Schultz, J. and Markowetz, F.
PLoS ONE 5
(12): e15788.
31 December 2010
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.
Schwarz, R.F., Ng, C.K.Y., Cooke, S.L., Newman, S., Temple, J., Piskorz, A.M., Gale, D., Sayal, K., Murtaza, M., Baldwin, P.J., Rosenfeld, N., Earl, H.M., Sala, E., Jimenez-Linan, M., Parkinson, C.A., Markowetz, F. and Brenton, J.D.
PLoS Medicine 12
(2): e1001789.
24 February 2015
ALVIS: interactive non-aggregative visualization and explorative analysis of multiple sequence alignments.
Schwarz, R.F., Tamuri, A.U., Kultys, M., King, J., Godwin, J., Florescu, A.M., Schultz, J. and Goldman, N.
Nucleic Acids Research 44
(8): e77.
5 May 2016
Phylogenetic quantification of intra-tumour heterogeneity.
Schwarz, R.F., Trinh, A., Sipos, B., Brenton, J.D., Goldman, N. and Markowetz, F.
PLoS Computational Biology 10
(4): e1003535.
17 April 2014
Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells.
Schwarzer, R., Doerken, B. and Jundt, F.
Leukemia 26
(4): 806-813.
April 2012
Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model.
Schwarzer, R., Nickel, N., Godau, J., Willie, B.M., Duda, G.N., Schwarzer, R., Cirovic, B., Leutz, A., Manz, R., Bogen, B., Dörken, B. and Jundt, F.
Blood Cancer Journal 4
: e217.
13 June 2014
GTP-dependent scaffold formation in the GTPase of Immunity Associated Protein family.
Schwefel, D. and Daumke, O.
Small GTPases 2
(1): 27-30.
January 2011
Purification, crystallization and preliminary X-ray analysis of human GIMAP2.
Schwefel, D., Froehlich, C. and Daumke, O.
Acta Crystallographica Section F 66
(6): 725-729.
1 June 2010
Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Schwefel, D., Froehlich, C., Eichhorst, J., Wiesner, B., Behlke, J., Aravind, L. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 107
(47): 20299-20304.
23 November 2010
Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel, D., Arasu, B.S., Marino, S.F., Lamprecht, B., Köchert, K., Rosenbaum, E., Eichhorst, J., Wiesner, B., Behlke, J., Rocks, O., Mathas, S. and Daumke, O.
Structure 21
(4): 550-559.
2 April 2013
Evidence of neural crest cell origin of a DICER1 mutant CNS sarcoma in a child with DICER1 syndrome and NRAS-mutant neurocutaneous melanosis.
Schweizer, L., Hartmann, W., Koch, A., Nunninger, M., Thomale, U.W., Pennacchietti, V., Tietze, A., Horn, D., Pajtler, K.W., Hirsch, S., Wieland, I., Deubzer, H., Rossi, R., Hernáiz Driever, P., von Hoff, K. and von Zezschwitz, B.
Neuropathology and Applied Neurobiology 48
(6): e12830.
October 2022
PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.
Schönheit, J., Kuhl, C., Gebhardt, M.L., Klett, F.F., Riemke, P., Scheller, M., Huang, G., Naumann, R., Leutz, A., Stocking, C., Priller, J., Andrade-Navarro, M.A. and Rosenbauer, F.
Cell Reports 3
(5): 1617-1628.
30 May 2013
Cantharidin and its analogue norcantharidin inhibit metastasis-inducing genes S100A4 and MACC1.
Schöpe, P.C., Zinnow, V., Ishfaq, M.A., Smith, J., Herrmann, P., Shoemaker, R.H., Walther, W. and Stein, U.
International Journal of Molecular Sciences 24
(2): 1179.
7 January 2023
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Schütte, M., Risch, T., Abdavi-Azar, N., Boehnke, K., Schumacher, D., Keil, M., Yildiriman, R., Jandrasits, C., Borodina, T., Amstislavskiy, V., Worth, C.L., Schweiger, C., Liebs, S., Lange, M., Warnatz, H.J., Butcher, L.M., Barrett, J.E., Sultan, M., Wierling, C., Golob-Schwarzl, N., Lax, S., Uranitsch, S., Becker, M., Welte, Y., Regan, J.L., Silvestrov, M., Kehler, I., Fusi, A., Kessler, T., Herwig, R., Landegren, U., Wienke, D., Nilsson, M., Velasco, J.A., Garin-Chesa, P., Reinhard, C., Beck, S., Schäfer, R., Regenbrecht, C.R.A., Henderson, D., Lange, B., Haybaeck, J., Keilholz, U., Hoffmann, J., Lehrach, H. and Yaspo, M.L.
Nature Communications 8
: 14262.
10 February 2017
How drag sharpens a T cell's view on antigen.
Schütz, G.J. and Huppa, J.B.
Proceedings of the National Academy of Sciences of the United States of America 116
(34): 16669-16671.
20 August 2019
The interactive complex between cytomegalovirus kinase vCDK/pUL97 and host factors CDK7-cyclin H determines individual patterns of transcription in infected cells.
Schütz, M., Cordsmeier, A., Wangen, C., Horn, A.H.C., Wyler, E., Ensser, A., Sticht, H. and Marschall, M.
International Journal of Molecular Sciences 24
(24): 17421.
13 December 2023
Myc depletion induces a pluripotent dormant state mimicking diapause.
Scognamiglio, R., Cabezas-Wallscheid, N., Thier, M.C., Altamura, S., Reyes, A., Prendergast, Á.M., Baumgärtner, D., Carnevalli, L.S., Atzberger, Ann, Haas, S., von Paleske, L., Boroviak, T., Wörsdörfer, P., Essers, M.A.G., Kloz, U., Eisenman, R.N., Edenhofer, F., Bertone, P., Huber, W., van der Hoeven, F., Smith, A. and Trumpp, A.
Cell 164
(4): 668-680.
11 February 2016
Dual linkage of a locus to left ventricular mass and a cardiac gene co-expression network driven by a chromosome domain.
Scott-Boyer, M.P., Praktiknjo, S.D., Llamas, B., Picard, S. and Deschepper, C.F.
Frontiers in Cardiovascular Medicine 1
: 11.
10 December 2014
Broadening the phenotypic and molecular spectrum of FINCA syndrome: Biallelic NHLRC2 variants in 15 novel individuals.
Sczakiel, H.L., Zhao, M., Wollert-Wulf, B., Danyel, M., Ehmke, N., Stoltenburg, C., Damseh, N., Al-Ashhab, M., Balci, T.B., Osmond, M., Andrade, A., Schallner, J., Porrmann, J., McDonald, K., Liao, M., Oppermann, H., Platzer, K., Dierksen, N., Mojarrad, M., Eslahi, A., Bakaeean, B., Calame, D.G., Lupski, J.R., Firoozfar, Z., Seyedhassani, S.M., Mohammadi, S.A., Anwaar, N., Rahman, F., Seelow, D., Janz, M., Horn, D., Maroofian, R. and Boschann, F.
European Journal of Human Genetics 31
(8): 905-317.
August 2023
Impairment of circulating myeloid dendritic cells in immunosuppressed renal/pancreas transplant recipients.
Sebelin, K., Schulzki, A., Kloetzel, P.M., Doerken, B., Pezzutto, A. and Subklewe, M.
Transplantation 82
(6): 779-787.
27 September 2006
Quantitative analysis of EBV-specific CD4/CD8 T cell numbers, absolute CD4/CD8 T cell numbers and EBV load in solid organ transplant recipients with PLTD.
Sebelin-Wulf, K., Nguyen, T.D., Oertel, S., Papp-Vary, M., Trappe, R., Schulzki, A., Pezzutto, A., Riess, H. and Subklewe, M.
Transplant Immunology 17
(3): 203-210.
April 2007
Transmitter- and hormone-activated Ca(2+) responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca(2+) sensor.
Seifert, S., Pannell, M., Uckert, W., Faerber, K. and Kettenmann, H.
Cell Calcium 49
(6): 365-375.
June 2011
A network of clinically and functionally relevant genes is involved in the reversion of the tumorigenic phenotype of MDA-MB-231 breast cancer cells after transfer of human chromosome 8.
Seitz, S., Frege, R., Jacobsen, A., Weimer, J., Arnold, W., Haefen, C.v., Niederacher, D., Schmutzler, R., Arnold, N. and Scherneck, S.
Oncogene 24
(5): 869-879.
1 January 2005
Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression.
Seitz, S., Korsching, E., Weimer, J., Jacobsen, A., Arnold, N., Meindl, A., Arnold, W., Gustavus, D., Klebig, C., Petersen, I. and Scherneck, S.
Genes Chromosomes & Cancer 45
(6): 612-627.
June 2006
Host cell interactome of tyrosine-phosphorylated bacterial proteins.
Selbach, M., Paul, F.E., Brandt, S., Guye, P., Daumke, O., Backert, S., Dehio, C. and Mann, M.
Cell Host & Microbe 5
(4): 397-403.
23 April 2009
CELDA - an ontology for the comprehensive representation of cells in complex systems.
Seltmann, S., Stachelscheid, H., Damaschun, A., Jansen, L., Lekschas, F., Fontaine, J.F., Nguyen-Dobinsky, T.N., Leser, U. and Kurtz, A.
BMC Bioinformatics 14
: 228.
17 July 2013
Impact of abutment rotation and angulation on marginal fit: theoretical considerations.
Semper, W., Kraft, S., Mehrhof, J. and Nelson, K.
International Journal of Oral & Maxillofacial Implants 25
(4): 752-758.
July 2010
Phosphorylation of PACSIN2 by protein kinase C triggers the removal of caveolae from the plasma membrane.
Senju, Y., Rosenbaum, E., Shah, C., Hamada-Nakahara, S., Itoh, Y., Yamamoto, K., Hanawa-Suetsugu, K., Daumke, O. and Suetsugu, S.
Journal of Cell Science 128
(15): 2766-2780.
1 August 2015
Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epithelial-mesenchymal transition in non-small-cell lung cancer.
Serresi, M., Gargiulo, G., Proost, N., Siteur, B., Cesaroni, M., Koppens, M., Xie, H., Sutherland, K.D., Hulsman, D., Citterio, E., Orkin, S., Berns, A. and van Lohuizen, M.
Cancer Cell 29
(1): 17-31.
11 January 2016
Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition.
Serresi, M., Kertalli, S., Li, L., Schmitt, M.J., Dramaretska, Y., Wierikx, J., Hulsman, D. and Gargiulo, G.
Science Advances 7
(9): eabd7974.
24 February 2021
Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Serresi, M., Siteur, B., Hulsman, D., Company, C., Schmitt, M.J., Lieftink, C., Morris, B., Cesaroni, M., Proost, N., Beijersbergen, R.L., van Lohuizen, M. and Gargiulo, G.
Journal of Experimental Medicine 215
(12): 3115.
3 December 2018
Bacteriophage P22 tailspike: structure of the complete protein and function of the interdomain linker.
Seul, A., Müller, J.J., Andres, D., Stettner, E., Heinemann, U. and Seckler, R.
Acta Crystallographica Section D 70
(Pt 5): 1336-1345.
May 2014
A mouse model of X-linked chronic granulomatous disease for the development of CRISPR/Cas9 gene therapy.
Sevim-Wunderlich, S., Dang, T., Rossius, J., Schnütgen, F. and Kuehn, R.
Genes 15
(6): 706.
June 2024
The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation.
Shabek, N., Herman-Bachinsky, Y., Buchsbaum, S., Lewinson, O., Haj-Yahya, M., Hejjaoui, M., Lashuel, H.A., Sommer, T., Brik, A. and Ciechanover, A.
Molecular Cell 48
(1): 87-97.
12 October 2012
The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Shah, S.P., Roth, A., Goya, R., Oloumi, A., Ha, G., Zhao, Y., Turashvili, G., Ding, J., Tse, K., Haffari, G., Bashashati, A., Prentice, L.M., Khattra, J., Burleigh, A., Yap, D., Bernard, V., McPherson, A., Shumansky, K., Crisan, A., Giuliany, R., Heravi-Moussavi, A., Rosner, J., Lai, D., Birol, I., Varhol, R., Tam, A., Dhalla, N., Zeng, T., Ma, K., Chan, S.K., Griffith, M., Moradian, A., Cheng, S.W.G., Morin, G.B., Watson, P., Gelmon, K., Chia, S., Chin, S.F., Curtis, C., Rueda, O.M., Pharoah, P.D., Damaraju, S., Mackey, J., Hoon, K., Harkins, T., Tadigotla, V., Sigaroudinia, M., Gascard, P., Tlsty, T., Costello, J.F., Meyer, I.M., Eaves, C.J., Wasserman, W.W., Jones, S., Huntsman, D., Hirst, M., Caldas, C., Marra, M.A. and Aparicio, S.
Nature 486
(7403): 395-399.
21 June 2012
Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C., Hegde, B.G., Morén, B., Behrmann, E., Mielke, T., Moenke, G., Spahn, C.M., Lundmark, R., Daumke, O. and Langen, R.
Structure 22
(3): 409-420.
4 March 2014
A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants.
Shahan, R., Hsu, C.W., Nolan, T.M., Cole, B.J., Taylor, I.W., Greenstreet, L., Zhang, S., Afanassiev, A., Vlot, A.H.C., Schiebinger, G., Benfey, P.N. and Ohler, U.
Developmental Cell 57
(4): 543-560.
28 February 2022
Interleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis.
Shalapour, S., Deiser, K., Kuehl, A.A., Glauben, R., Krug, S.M., Fischer, A., Sercan, O., Chappaz, S., Bereswill, S., Heimesaat, M.M., Loddenkemper, C., Fromm, M., Finke, D., Haemmerling, G.J., Arnold, B., Siegmund, B. and Schueler, T.
PLoS ONE 7
(2): e31939.
27 February 2012
Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo.
Shalapour, S., Deiser, K., Sercan, O., Tuckermann, J., Minnich, K., Willimsky, G., Blankenstein, T., Haemmerling, G.J., Arnold, B. and Schueler, T.
European Journal of Immunology 40
(9): 2391-2400.
September 2010
Leukemia-associated genetic aberrations in mesenchymal stem cells of children with acute lymphoblastic leukemia.
Shalapour, S., Eckert, C., Seeger, K., Pfau, M., Prada, J., Henze, G., Blankenstein, T. and Kammertoens, T.
Journal of Molecular Medicine 88
(3): 249-265.
March 2010
The thalidomide analogue, CC-4047, induces apoptosis signaling and growth arrest in childhood acute lymphoblastic leukemia cells in vitro and in vivo.
Shalapour, S., Zelmer, A., Pfau, M., Moderegger, E., Costa-Blechschmidt, C., van Landeghem, F.K., Taube, T., Fichtner, I., Buehrer, C., Henze, G., Seeger, K. and Wellmann, S.
Clinical Cancer Research 12
(18): 5526-5532.
15 September 2006
The effects of common structural variants on 3D chromatin structure.
Shanta, O., Noor, A. and Sebat, J.
BMC Genomics 21
(1): 95.
30 January 2020
Molecular contacts of ribose-phosphate backbone of mRNA with human ribosome.
Sharifulin, D.E., Grosheva, A.S., Bartuli, Y.S., Malygin, A.A., Meschaninova, M.I., Ven'yaminova, A.G., Stahl, J., Graifer, D.M. and Karpova, G.G.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1849
(8): 930-939.
August 2015
Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver.
Sharma, A.D., Cantz, T., Richter, R., Eckert, K., Henschler, R., Wilkens, L., Jochheim-Richter, A., Arseniev, L. and Ott, M.
American Journal of Pathology 167
(2): 555-564.
1 August 2005
MEK Partner 1 (MP1): Regulation of oligomerization in MAP kinase signaling.
Sharma, C., Vomastek, T., Tarcsafalvi, A., Catling, A.D., Schaeffer, H.J., Eblen, S.T. and Weber, M.J.
Journal of Cellular Biochemistry 94
(4): 708-719.
1 January 2005
K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.
Shearer, R.F., Typas, D., Coscia, F., Schovsbo, S., Kruse, T., Mund, A. and Mailand, N.
EMBO Journal 41
(9): e110145.
2 May 2022
Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E., McShane, E., Cheret, C., Walcher, J., Müller, T., Wulf-Goldenberg, A., Hoelper, S., Garratt, A.N., Krüger, M., Rajewsky, K., Meijer, D., Birchmeier, W., Lewin, G.R., Selbach, M. and Birchmeier, C.
Genes & Development 28
(3): 290-303.
1 February 2014
Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain.
Sheinman, M., Arkhipova, K., Arndt, P.F., Dutilh, B.E., Hermsen, R. and Massip, F.
eLife 10
: e62719.
9 July 2021
PCNA-mediated degradation of p21 coordinates the DNA damage response and cell cycle regulation in individual cells.
Sheng, C., Mendler, I.H., Rieke, S., Snyder, P., Jentsch, M., Friedrich, D., Drossel, B. and Loewer, A.
Cell Reports 27
(1): 48-58.
2 April 2019
Comparison of inter- and intraspecies variation in humans and fruit flies.
Shih, J., Hodge, R. and Andrade-Navarro, M.A.
Genomics Data 3
: 49-54.
March 2015
TAK1 adaptor proteins TAB2 and TAB3 link the signalosome to B cell receptor-induced IKK activation.
Shinohara, H., Yasuda, T. and Kurosaki, T.
FEBS Letters 590
(18): 3264-3269.
September 2016
Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Shortt, J., Martin, B.P., Newbold, A., Hannan, K.M., Devlin, J.R., Baker, A.J., Ralli, R., Cullinane, C., Schmitt, C.A., Reimann, M., Hall, M.N., Wall, M., Hannan, R.D., Pearson, R.B., McArthur, G.A. and Johnstone, R.W.
Blood 121
(15): 2964-2974.
11 April 2013
Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung.
Shu, W., Guttentag, S., Wang, Z., Andl, T., Ballard, P., Lu, M.M., Piccolo, S., Birchmeier, W., Whitsett, J.A., Millar, S.E. and Morrisey, E.E.
Developmental Biology 283
(1): 226-239.
1 January 2005
Safety and efficacy of glofitamab for relapsed/refractory large B-cell lymphoma in a multinational real-world study.
Shumilov, E., Wurm-Kuczera, R., Kerkhoff, A., Wang, M., Melchardt, T., Holtick, U., Bacher, U., Staber, P.B., Mazzeo, P., Leng, C., Böckle, D., Hölscher, A.S., Kauer, J., Rotter, N., Vucinic, V., Rudzki, J.D., Nachbaur, D., Bücklein, V.L., Schnetzke, U., Krämer, I., Wille, K., Hasse, A., von Tresckow, B., Hänel, M., Koenecke, C., Velazquez, G.F., Viardot, A., Schmid, C., Thurner, L., Wolf, D., Subklewe, M., Dreyling, M., Dreger, P., Dietrich, S., Keller, U., Jäger, U., Greil, R., Pabst, T., Lenz, G. and Chapuy, B.
Blood Advances
: bloodadvances.2024014903.
11 December 2024
(In Press)
Preoperative short-course radiotherapy versus combined radiochemotherapy in locally advanced rectal cancer: a multi-centre prospectively randomised study of the Berlin Cancer Society.
Siegel, R., Burock, S., Wernecke, K.D., Kretzschmar, A., Dietel, M., Loy, V., Koswig, S., Budach, V. and Schlag, P.M.
BMC Cancer 9
(1): 50.
6 February 2009
Response to Preoperative short-course radiotherapy in locally advanced rectal cancer: Value of F-fluorodeoxyglucose positron emission tomography.
Siegel, R., Dresel, S., Koswig, S., Gebauer, B., Huenerbein, M., Schneider, W. and Schlag, P.M.
Onkologie 31
(4): 166-172.
April 2008
Hepatic arterial Fotemustine chemotherapy in patients with liver metastases from cutaneous melanoma is as effective as in ocular melanoma.
Siegel, R., Hauschild, A., Kettelhack, C., Kaehler, K.C., Bembenek, A. and Schlag, P.M.
European Journal of Surgical Oncology 33
(5): 627-632.
June 2007
Lokale nicht-virale Gentherapie in kutanen Metastasen von Mammakarzinom und Melanom: Ergebnisse einer Phase-I-Studie mittels Jet-Injektion nackter DNA.
Siegel, R., Kobelt, D., Knoesel, T., Stein, U., Schlag, P.M. and Walther, W.
Chirurgisches Forum 2008 37
: 131-132.
2008
GIPC1 regulates MACC1-driven metastasis.
Siegel, F., Schmidt, H., Juneja, M., Smith, J., Herrmann, P., Kobelt, D., Sharma, K., Fichtner, I., Walther, W., Dittmar, G., Volkmer, R., Rathjen, F.G., Schlag, P.M. and Stein, U.
Frontiers in Oncology 13
: 1280977.
8 December 2023
Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Sigal, M., Logan, C.Y., Kapalczynska, M., Mollenkopf, H.J., Berger, H., Wiedenmann, B., Nusse, R., Amieva, M.R. and Meyer, T.F.
Nature 548
(7668): 451-455.
24 August 2017
Neuroendokrine Neoplasien des gastroenteropankreatischen Systems [Gastroenteropancreatic neuro-endocrine neoplasms].
Sigal, M., Pape, F. and Wiedenmann, B.
Therapeutische Umschau 69
(10): 591-596.
October 2012
Helicobacter pylori activates and expands Lgr5(+) stem cells through direct colonization of the gastric glands.
Sigal, M., Rothenberg, M.E., Logan, C.Y., Lee, J.Y., Honaker, R.W., Cooper, R.L., Passarelli, B., Camorlinga, M., Bouley, D.M., Alvarez, G., Nusse, R., Torres, J. and Amieva, M.R.
Gastroenterology 148
(7): 1392-1404.
June 2015
Darbepoetin-α inhibits the perpetuation of necro-inflammation and delays the progression of cholestatic fibrosis in mice.
Sigal, M., Siebert, N., Zechner, D., Menschikow, E., Abshagen, K., Vollmar, B. and Eipel, C.
Laboratory Investigation 90
(10): 1447-1456.
October 2010
The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay.
Silla, T., Schmid, M., Dou, Y., Garland, W., Milek, M., Imami, K., Johnsen, D., Polak, P., Andersen, J.S., Selbach, M., Landthaler, M. and Jensen, T.
Nucleic Acids Research 48
(5): 2518-2530.
18 March 2020
Recessive mutations in PCBD1 cause a new type of early-onset diabetes.
Simaite, D., Kofent, J., Gong, M., Rüschendorf, F., Jia, S., Arn, P., Bentler, K., Ellaway, C., Kühnen, P., Hoffmann, G.F., Blau, N., Spagnoli, F.M., Hübner, N. and Raile, K.
Diabetes 63
(10): 3557-3564.
October 2014
Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth.
Simmons, D.G., Natale, D.R., Begay, V., Hughes, M., Leutz, A. and Cross, J.C.
Development 135
(12): 2083-2091.
June 2008
Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a piwi protein.
Simon, B., Kirkpatrick, J.P., Eckhardt, S., Reuter, M., Rocha, E.A., Andrade-Navarro, M.A., Sehr, P., Pillai, R.S. and Carlomagno, T.
Structure 19
(2): 172-180.
9 February 2011
2017 GPOH guidelines for diagnosis and treatment of patients with neuroblastic tumors.
Simon, T., Hero, B., Schulte, J.H., Deubzer, H., Hundsdoerfer, P., von Schweinitz, D., Fuchs, J., Schmidt, M., Prasad, V., Krug, B., Timmermann, B., Leuschner, I., Fischer, M., Langer, T., Astrahantseff, K., Berthold, F., Lode, H. and Eggert, A.
Klinische Padiatrie 229
(3): 147-167.
May 2017
Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery.
Simonetti, G., Padella, A., do Valle, I.F., Fontana, M.C., Fonzi, E., Bruno, S., Baldazzi, C., Guadagnuolo, V., Manfrini, M., Ferrari, A., Paolini, S., Papayannidis, C., Marconi, G., Franchini, E., Zuffa, E., Laginestra, M.A., Zanotti, F., Astolfi, A., Iacobucci, I., Bernardi, S., Sazzini, M., Ficarra, E., Hernandez, J.M., Vandenberghe, P., Cools, J., Bullinger, L., Ottaviani, E., Testoni, N., Cavo, M., Haferlach, T., Castellani, G., Remondini, D. and Martinelli, G.
Cancer 125
(5): 712-725.
1 March 2019
Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways.
Simonetti, M., Agarwal, N., Stösser, S., Bali, K.K., Karaulanov, E., Kamble, R., Pospisilova, B., Kurejova, M., Birchmeier, W., Niehrs, C., Heppenstall, P. and Kuner, R.
Neuron 83
(1): 104-121.
2 July 2014
A 3D model of a human epiblast reveals BMP4-driven symmetry breaking.
Simunovic, M., Metzger, J.J., Etoc, F., Yoney, A., Ruzo, A., Martyn, I., Croft, G., You, D.S., Brivanlou, A.H. and Siggia, E.D.
Nature Cell Biology 21
(7): 900-910.
July 2019
Peripheral blood sCD3(-) CD4(+) T cells: a useful diagnostic tool in angioimmunoblastic T cell lymphoma.
Singh, A., Schabath, R., Ratei, R., Stroux, A., Klemke, C.D., Nebe, T., Flörcken, A., van Lessen, A., Anagnostopoulos, I., Dörken, B., Ludwig, W.D., Pezzutto, A. and Westermann, J.
Hematological Oncology 32
(1): 16-21.
March 2014
Graph neural networks for learning molecular excitation spectra.
Singh, K., Münchmeyer, J., Weber, L., Leser, U. and Bande, A.
Journal of Chemical Theory and Computation 18
(7): 4408-4417.
12 July 2022
A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish.
Singh, S.P., Chawla, P., Hnatiuk, A., Kamel, M., Silva, L.D., Spanjaard, B., Eski, S.E., Janjuha, S., Olivares-Chauvet, P., Kayisoglu, O., Rost, F., Bläsche, J., Kränkel, A., Petzold, A., Kurth, T., Reinhardt, S., Junker, J.P. and Ninov, N.
Development 149
(2): dev199853.
January 2022
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.
Singh, Y., Trautwein, C., Fendel, R., Krickeberg, N., Berezhnoy, G., Bissinger, R., Ossowski, S., Salker, M.S., Casadei, N. and Riess, O.
Heliyon 7
(6): e07147.
June 2021
Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy.
Sinha Ray, S., Dutta, D., Dennys, C., Powers, S., Roussel, F., Lisowski, P., Glažar, P., Zhang, X., Biswas, P., Caporale, J.R., Rajewsky, N., Bickle, M., Wein, N., Bellen, H.J., Likhite, S., Marcogliese, P.C. and Meyer, K.C.
Cell Reports 41
(10): 111751.
6 December 2022
Morphology and ultrastructure of the chorioallantoic placenta of the Iberian mole (Talpa occidentalis) with special reference to heterophagous areolas and the nature of interhaemal barrier.
Siniza, S., Lupianez, D.G., Jimenez, R. and Zeller, U.
Journal of Anatomy 221
(2): 164-173.
August 2012
Second-line treatment in pancreatic cancer patients: Who profits? Results from the CONKO study group.
Sinn, M., Daelken, L., Striefler, J.K., Bischoff, S., Schweitzer, N., Pelzer, U., Doerken, B., Riess, H. and Stieler, J.M.
Pancreas 45
(4): 601-605.
April 2016
α-smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study.
Sinn, M., Denkert, C., Striefler, J.K., Pelzer, U., Stieler, J.M., Bahra, M., Lohneis, P., Doerken, B., Oettle, H., Riess, H. and Sinn, B.V.
British Journal of Cancer 111
(10): 1917-1923.
11 November 2014
Hepatic arterial infusion with oxaliplatin and 5-FU/folinic acid for advanced biliary tract cancer: a phase II study.
Sinn, M., Nicolaou, A., Gebauer, B., Podrabsky, P., Seehofer, D., Ricke, J., Doerken, B., Riess, H. and Hildebrandt, B.
Digestive Diseases and Sciences 58
(8): 2399-2405.
August 2013
Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with primary liver cancer: a phase II-study (NCT00356161).
Sinn, M., Nicolaou, A., Ricke, J., Podrabsky, P., Seehofer, D., Gebauer, B., Pech, M., Neuhaus, P., Doerken, B., Riess, H. and Hildebrandt, B.
BMC Gastroenterology 13
: 125.
9 August 2013
SPARC expression in resected pancreatic cancer patients treated with Gemcitabine: results from the CONKO-001 study.
Sinn, M., Sinn, B.V., Striefler, J.K., Lindner, J.L., Stieler, J.M., Lohneis, P., Bischoff, S., Blaeker, H., Pelzer, U., Neuhaus, P., Dietel, M., Doerken, B., Oettle, H., Riess, H. and Denkert, C.
Annals of Oncology 25
(5): 1025-1032.
May 2014
Does long-term survival in patients with pancreatic cancer really exist? Results from the CONKO-001 study.
Sinn, M., Striefler, J.K., Sinn, B.V., Sallmon, D., Bischoff, S., Stieler, J.M., Pelzer, U., Bahra, M., Neuhaus, P., Doerken, B., Denkert, C., Riess, H. and Oettle, H.
Journal of Surgical Oncology 108
(6): 398-402.
November 2013
Multiple sclerosis lesions and irreversible brain tissue damage: a comparative ultrahigh-field strength magnetic resonance imaging study.
Sinnecker, T., Mittelstaedt, P., Doerr, J., Pfueller, C.F., Harms, L., Niendorf, T., Paul, F. and Wuerfel, J.
Archives of Neurology 69
(6): 739-745.
June 2012
Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes.
Sinzelle, L., Kapitonov, V.V., Grzela, D.P., Jursch, T., Jurka, J., Izsvak, Z. and Ivics, Z.
Proceedings of the National Academy of Sciences of the United States of America 105
(12): 4715-4720.
25 March 2008
The viral and cellular microRNA targetome in lymphoblastoid cell lines.
Skalsky, R.L., Corcoran, D.L., Gottwein, E., Frank, C.L., Kang, D., Hafner, M., Nusbaum, J.D., Feederle, R., Delecluse, H.J., Luftig, M.A., Tuschl, T., Ohler, U. and Cullen, B.R.
PLoS Pathogens 8
(1): e1002484.
26 January 2012
Using internal and collective variables in Monte Carlo simulations of nucleic acid structures: Chain breakage/closure algorithm and associated Jacobians.
Sklenar, H., Wuestner, D. and Rohs, R.
Journal of Computational Chemistry 27
(3): 309-315.
February 2006
CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment.
Skroblyn, T., Joedicke, J.J., Pfau, M., Krüger, K., Bourquin, J.P., Izraeli, S., Eckert, C. and Höpken, U.E.
Journal of Pathology 258
(1): 12-25.
September 2022
Statistical properties and information content of calcium oscillations.
Skupin, A. and Falcke, M.
Genome Informatics 18
: 44-53.
2007
Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis.
Smink, J.J., Tunn, P.U. and Leutz, A.
Journal of Molecular Medicine 90
(1): 25-30.
January 2012
Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB.
Smink, J.J., Bégay, V., Schoenmaker, T., Sterneck, E., de Vries, T.J. and Leutz, A.
EMBO Journal 28
(12): 1769-1781.
17 June 2009
Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma.
Smith, J.R., Braziel, R.M., Paoletti, S., Lipp, M., Uguccioni, M. and Rosenbaum, J.T.
Blood 101
(3): 815-821.
1 February 2003
Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes.
Smith, S.N., Sommermeyer, D., Piepenbrink, K.H., Blevins, S.J., Bernhard, H., Uckert, W., Baker, B.M. and Kranz, D.M.
Journal of Molecular Biology 425
(22): 4496-4507.
15 November 2013
Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: comparative analysis using six species of bathyergidae.
Smith, E.S.J., Purfürst, B., Grigoryan, T., Park, T.J., Bennett, N.C. and Lewin, G.R.
Journal of Comparative Neurology 520
(12): 2785-2803.
15 August 2012
Characterization of CD8 T cell-mediated mutations in the immunodominant epitope GP33-41 of lymphocytic choriomeningitis virus.
Smyth, M., Khamina, K., Popa, A., Gudipati, V., Agerer, B., Lercher, A., Kosack, L., Endler, L., Baazim, H., Viczenczova, C., Huppa, J.B. and Bergthaler, A.
Frontiers in Immunology 12
: 638485.
14 June 2021
Outcomes with intensive treatment for acute myeloid leukemia: an analysis of two decades of data from the HARMONY Alliance.
Sobas, M.A., Turki, A.T., Ramiro, A.V., Sánchez, A.H., Elicegui, J.M., González, T., Melchor, R.A., Abáigar, M., Tur, L., Dall'Olio, D., Sträng, E., Tettero, J.M., Castellani, G., Benner, A., Döhner, K., Thiede, C., Metzeler, K.H., Haferlach, T., Damm, F., Ayala, R., Martínez-López, J., Mills, K.I., Sierra, J., Lehmann, S., Porta, M.G.D., Mayer, J., Reinhardt, D., Medina, R.V., Schulze-Rath, R., Barbus, M., Hernández-Rivas, J.M., Huntly, B.J.P., Ossenkoppele, G., Döhner, H. and Bullinger, L.
Haematologica
7 November 2024
(In Press)
Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology.
Sogues, A., Leigh, K., Halingstad, E.V., Van der Verren, S.E., Cecil, A.J., Fioravanti, A., Pak, A.J., Kudryashev, M. and Remaut, H.
Proceedings of the National Academy of Sciences of the United States of America 121
(51): e2415351121.
17 December 2024
A gene regulatory program for meiotic prophase in the fetal ovary.
Soh, Y.Q.S., Junker, J.P., Gill, M.E., Mueller, J.L., van Oudenaarden, A. and Page, D.C.
PLoS Genetics 11
(9): e1005531.
17 September 2015
Bacteriophages: emerging applications in medicine, food, and biotechnology.
Sohail, H.A., Coffey, A., Debrowska, K., Meyer, I.M., Middelboe, M., Sohail, M. and Clokie, M.R.J.
PHAGE 1
(2): 75-82.
16 June 2020
High prevalence and breast cancer predisposing role of the BLMc.1642 C>T (Q548X) mutation in Russia.
Sokolenko, A.P., Iyevleva, A.G., Preobrazhenskaya, E.V., Mitiushkina, N.V., Abysheva, S.N., Suspitsin, E.N., Kuligina, E.S., Gorodnova, T.V., Pfeifer, W., Togo, A.V., Turkevich, E.A., Ivantsov, A.O., Voskresenskiy, D.V., Dolmatov, G.D., Bit-Sava, E.M., Matsko, D.E., Semiglazov, V.F., Fichtner, I., Larionov, A.A., Kuznetsov, S.G., Antoniou, A.C. and Imyanitov, E.N.
International Journal of Cancer 130
(12): 2867-2873.
15 June 2012
The CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiation.
Solana, J., Gamberi, C., Mihaylova, Y., Grosswendt, S., Chen, C., Lasko, P., Rajewsky, N. and Aboobaker, A.A.
PLoS Genetics 9
(12): e1004003.
December 2013
Caipirini: using gene sets to rank literature.
Soldatos, T.G., O'Donoghue, S.I., Satagopam, V.P., Barbosa-Silva, A., Pavlopoulos, G.A., Wanderley-Nogueira, A.C., Soares-Cavalcanti, N.M. and Schneider, R.
BioData Mining 5
(1): 1.
1 February 2012
Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy.
Sommariva, E., Stadiotti, I., Casella, M., Catto, V., Dello Russo, A., Carbucicchio, C., Arnaboldi, L., De Metrio, S., Milano, G., Scopece, A., Casaburo, M., Andreini, D., Mushtaq, S., Conte, E., Chiesa, M., Birchmeier, W., Cogliati, E., Paolin, A., König, E., Meraviglia, V., De Musso, M., Volani, C., Cattelan, G., Rauhe, W., Turnu, L., Porro, B., Pedrazzini, M., Camera, M., Corsini, A., Tondo, C., Rossini, A. and Pompilio, G.
EMBO Molecular Medicine 13
(9): e14365.
7 September 2021
Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
Sommermann, T., Yasuda, T., Ronen, J., Wirtz, T., Weber, T., Sack, U., Caeser, R., Zhang, J., Li, X., Chu, V.T., Jauch, A., Unger, K., Hodson, D.J., Akalin, A. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 117
(25): 14421-14432.
23 June 2020
Designer T cells by T cell receptor replacement.
Sommermeyer, D., Neudorfer, J., Weinhold, M., Leisegang, M., Engels, B., Noessner, E., Heemskerk, M.H., Charo, J., Schendel, D.J., Blankenstein, T., Bernhard, H. and Uckert, W.
European Journal of Immunology 36
(11): 3052-3059.
November 2006
Minimal amino acid exchange in human TCR constant regions fosters improved function of TCR gene-modified T cells.
Sommermeyer, D. and Uckert, W.
Journal of Immunology 184
(11): 6223-6231.
1 June 2010
NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability.
Sommermeyer, D., Conrad, H., Krönig, H., Gelfort, H., Bernhard, H. and Uckert, W.
International Journal of Cancer 132
(6): 1360-1367.
15 March 2013
Homology-directed repair protects the replicating genome from metabolic assaults.
Somyajit, K., Spies, J., Coscia, F., Kirik, U., Rask, M.B., Lee, J.H., Neelsen, K.J., Mund, A., Jensen, L.J., Paull, T.T., Mann, M. and Lukas, J.
Developmental Cell 56
(4): 461-477.
22 February 2021
A SEPT1-based scaffold is required for Golgi integrity and function.
Song, K., Gras, C., Capin, G., Gimber, N., Lehmann, M., Mohd, S., Puchkov, D., Rödiger, M., Wilhelmi, I., Daumke, O., Schmoranzer, J., Schürmann, A. and Krauss, M.
Journal of Cell Science 132
(3): jcs225557.
1 February 2019
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
Sonnet, M., Claus, R., Becker, N., Zucknick, M., Petersen, J., Lipka, D.B., Oakes, C.C., Andrulis, M., Lier, A., Milsom, M.D., Witte, T., Gu, L., Kim-Wanner, S.Z., Schirmacher, P., Wulfert, M., Gattermann, N., Lübbert, M., Rosenbauer, F., Rehli, M., Bullinger, L., Weichenhan, D. and Plass, C.
Genome Medicine 6
(4): 34.
2014
Predictive factors for the benefit of perioperative FOLFOX for resectable liver metastasis in colorectal cancer patients (EORTC Intergroup trial 40983).
Sorbye, H., Mauer, M., Gruenberger, T., Glimelius, B., Poston, G.J., Schlag, P.M., Rougier, P., Bechstein, W.O., Primrose, J.N., Walpole, E.T., Finch-Jones, M., Jaeck, D., Mirza, D., Parks, R.W., Collette, L., Cutsem, E.V., Scheithauer, W., Lutz, M.P. and Nordlinger, B.
Annals of Surgery 255
(3): 534-539.
March 2012
Genetic interaction between Wnt/β-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Soshnikova, N., Zechner, D., Huelsken, J., Mishina, Y., Behringer, R.R., Taketo, M.M., Crenshaw, E.B. and Birchmeier, W.
Genes & Development 17
(16): 1963-1968.
1 January 2003
Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells.
Soucie, E.L., Weng, Z., Geirsdóttir, L., Molawi, K., Maurizio, J., Fenouil, R., Mossadegh-Keller, N., Gimenez, G., VanHille, L., Beniazza, M., Favret, J., Berruyer, C., Perrin, P., Hacohen, N., Andrau, J.C., Ferrier, P., Dubreuil, P., Sidow, A. and Sieweke, M.H.
Science 351
(6274): aad5510.
12 February 2016
Synthesis of GTP-derived Ras ligands.
Soulère, L., Aldrich, C., Daumke, O., Gail, R., Kissau, L., Wittinghofer, A. and Waldmann, H.
ChemBioChem 5
(10): 1448-53.
4 October 2004
Simultaneous lineage tracing and cell-type identification using CRISPR-Cas9-induced genetic scars.
Spanjaard, B., Hu, B., Mitic, N., Olivares-Chauvet, P., Janjuha, S., Ninov, N. and Junker, J.P.
Nature Biotechnology 36
(5): 469-473.
May 2018
The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.
Sparmann, A., Xie, Y., Verhoeven, E., Vermeulen, M., Lancini, C., Gargiulo, G., Hulsman, D., Mann, M., Knoblich, J.A. and van Lohuizen, M.
EMBO Journal 32
(11): 1598-1612.
29 May 2013
Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
Specker, E., Matthes, S., Wesolowski, R., Schütz, A., Grohmann, M., Alenina, N., Pleimes, D., Mallow, K., Neuenschwander, M., Gogolin, A., Weise, M., Pfeifer, J., Ziebart, N., Heinemann, U., von Kries, J.P., Nazaré, M. and Bader, M.
Journal of Medicinal Chemistry 65
(16): 11126-11149.
25 August 2022
Structure-based design of xanthine-imidazopyridines and -imidazothiazoles as highly potent and in vivo efficacious tryptophan hydroxylase inhibitors.
Specker, E., Wesolowski, R., Schütz, A., Matthes, S., Mallow, K., Wasinska-Kalwa, M., Winkler, L., Oder, A., Alenina, N., Pleimes, D., von Kries, J.P., Heinemann, U., Bader, M. and Nazaré, M.
Journal of Medicinal Chemistry 66
(21): 14866-14896.
9 November 2023
Chronic CD30-signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.
Sperling, S.A., Fiedler, P., Lechner, M., Pollithy, A., Ehrenberg, S., Schiefer, A.I., Kenner, L., Feuchtinger, A., Kühn, R., Swinerd, G., Schmidt-Supprian, M., Strobl, L.J. and Zimber-Strobl, U.
Blood 133
(24): 2597-2609.
13 June 2019
Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice.
Spielmann, M., Kakar, N., Tayebi, N., Leettola, C., Nürnberg, G., Sowada, N., Lupiáñez, D.G., Harabula, I., Flöttmann, R., Horn, D., Chan, W.L., Wittler, L., Yilmaz, R., Altmüller, J., Thiele, H., van Bokhoven, H., Schwartz, C.E., Nürnberg, P., Bowie, J.U., Ahmad, J., Kubisch, C., Mundlos, S. and Borck, G.
Genome Research 26
(2): 183-191.
February 2016
Tissue restricted expression and chromosomal localization of the YB-1 gene encoding a 42 kD nuclear CCAAT binding protein.
Spitkovsky, D.D., Royer-Pokora, B., Delius, H., Kisseljov, F., Jenkins, N.A., Gilbert, D.J., Copeland, N.G. and Royer, H.D.
Nucleic Acids Research 20
(4): 797-803.
25 February 1992
TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.
Spranger, S., Jeremias, I., Wilde, S., Leisegang, M., Staerck, L., Mosetter, B., Uckert, W., Heemskerk, M.H.M., Schendel, D.J. and Frankenberger, B.
Blood 119
(15): 3440-3449.
12 April 2012
Targeting KDM1A in neuroblastoma with NCL-1 induces a less aggressive phenotype and suppresses angiogenesis.
Sprüssel, A., Suzuki, T., Miyata, N., Astrahantseff, K., Szymansky, A., Toedling, J., Thole-Kliesch, T.M., Ballagee, A., Lodrini, M., Künkele, A., Truss, M., Heukamp, L.C., Mathia, S., Hertwig, F., Rosenberger, C., Eggert, A., Deubzer, H.E. and Schulte, J.H.
Journal of Clinical Medicine 13
(20): 6081.
October 2024
Red-edge anisotropy microscopy enables dynamic imaging of homo-FRET between green fluorescent proteins in cells.
Squire, A., Verveer, P.J., Rocks, O. and Bastiaens, P.I.
Journal of Structural Biology 147
(1): 62-69.
July 2004
Clinical use of the hyperthermia treatment planning system HyperPlan to predict effectiveness and toxicity.
Sreenivasa, G., Gellermann, J., Rau, B., Nadobny, J., Schlag, P.M., Deuflhard, P., Felix, R. and Wust, P.
International Journal of Radiation Oncology, Biology, Physics 55
(2): 407-419.
1 February 2003
PI3 kinase signals BCR-dependent mature B cell survival.
Srinivasan, L., Sasaki, Y., Calado, D.P., Zhang, B., Paik, J.H., DePinho, R.A., Kutok, J.L., Kearney, J.F., Otipoby, K.L. and Rajewsky, K.
Cell 139
(3): 573-586.
30 October 2009
Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Staber, P.B., Zhang, P., Ye, M., Welner, R.S., Nombela-Arrieta, C., Bach, C., Kerenyi, M., Bartholdy, B.A., Zhang, H., Alberich-Jorda, M., Lee, S., Yang, H., Ng, F., Zhang, J., Leddin, M., Silberstein, L.E., Hoefler, G., Orkin, S.H., Goettgens, B., Rosenbauer, F., Huang, G. and Tenen, D.G.
Molecular Cell 49
(5): 934-946.
7 March 2013
The splenic marginal zone shapes the phenotype of leukemia B cells and facilitates their niche-specific retention and survival.
Stache, V., Verlaat, L., Gätjen, M., Heinig, K., Westermann, J., Rehm, A. and Höpken, U.E.
OncoImmunology 6
(6): e1323155.
6 June 2017
Teratoma formation of human embryonic stem cells in three-dimensional perfusion culture bioreactors.
Stachelscheid, H., Wulf-Goldenberg, A., Eckert, K., Jensen, J., Edsbagge, J., Bjoerquist, P., Rivero, M., Strehl, R., Jozefczuk, J., Prigione, A., Adjaye, J., Urbaniak, T., Bussmann, P., Zeilinger, K. and Gerlach, J.C.
Journal of Tissue Engineering and Regenerative Medicine 7
(9): 729-741.
September 2013
CellFinder: a cell data repository.
Stachelscheid, H., Seltmann, S., Lekschas, F., Fontaine, J.F., Mah, N., Neves, M., Andrade-Navarro, M.A., Leser, U. and Kurtz, A.
Nucleic Acids Research 42
(1): D950-D958.
1 January 2014
The leukemogenicity of Hoxa9 depends on alternative splicing.
Stadler, C R, Vegi, N, Mulaw, M A, Edmaier, K E, Rawat, V P S, Dolnik, A, Bullinger, L., Heilmeier, B, Quintanilla-Fend, L, Spiekermann, K, Hiddemann, W, Döhner, K, Döhner, H, Feuring-Buske, M and Buske, C
Leukemia 28
(9): 1838-1843.
September 2014
Necrotic death but not irradiation abolishes costimulation of T-cell effector functions and survival by CD80-expressing tumor cells.
Staerck, L., Scholz, C., Blankenstein, T., Doerken, B. and Daniel, P.T.
International Journal of Cancer 116
(1): 78-86.
1 January 2005
Costimulation by CD137/4-1BB inhibits T cell apoptosis and induces Bcl-xL and c-FLIPshort via phosphatidylinositol 3-kinase and AKT/protein kinase B.
Staerck, L., Scholz, C., Doerken, B. and Daniel, P.T.
European Journal of Immunology 35
: 1257-1266.
1 January 2005
Consensus molecular subtypes as biomarkers of fluorouracil and folinic acid maintenance therapy with or without panitumumab in (RAS) wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212).
Stahler, A., Hoppe, B., Na, I.K., Keilholz, L., Müller, L., Karthaus, M., Fruehauf, S., Graeven, U., Fischer von Weikersthal, L., Goekkurt, E., Kasper, S., Kind, A.J., Kurreck, A., Alig, A.H.S., Held, S., Reinacher-Schick, A., Heinemann, V., Horst, D., Jarosch, A., Stintzing, S., Trarbach, T. and Modest, D.P.
Journal of Clinical Oncology 41
(16): 2975-2987.
1 June 2023
Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing.
Stangl, C., de Blank, S., Renkens, I., Westera, L., Verbeek, T., Valle-Inclan, J.E., Chamorro González, R., Henssen, A.G., van Roosmalen, M.J., Stam, R.W., Voest, E.E., Kloosterman, W.P., van Haaften, G. and Monroe, G.R.
Nature Communications 11
(1): 2861.
5 June 2020
Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas.
Staudacher, J.J., Arnold, A., Kühl, A.A., Pötzsch, M., Daum, S., Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. and Treese, C.
BMC Cancer 22
(1): 953.
5 September 2022
The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6.
Stauss, D., Brunner, C., Berberich-Siebelt, F., Höpken, U.E., Lipp, M. and Müller, G.
EMBO Journal 35
(8): 881-898.
15 April 2016
Cell differentiation mediated by co-culture of human umbilical cord blood stem cells with murine hepatic cells.
Stecklum, M., Wulf-Goldenberg, A., Purfürst, B., Siegert, A., Keil, M., Eckert, K. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 51
(2): 183-191.
February 2015
CYCLeR - a novel tool for the full isoform assembly and quantification of circRNAs.
Stefanov, S.R. and Meyer, I.M.
Nucleic Acids Research 51
(2): e10.
25 January 2023
Doxorubicin changes the spatial organization of the genome around active promoters.
Stefanova, M.E., Ing-Simmons, E., Stefanov, S., Flyamer, I., Dorado Garcia, H., Schöpflin, R., Henssen, A.G., Vaquerizas, J.M. and Mundlos, S.
Cells 12
(15): 2001.
4 August 2023
DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M., Denker, S. and Schmitt, C.A.
Cancers 14
(6): 1453.
11 March 2022
Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.
Steidl, U., Rosenbauer, F., Verhaak, R.G.W., Gu, X., Ebralidze, A., Otu, H.H., Klippel, S., Steidl, C., Bruns, I., Costa, D.B., Wagner, K., Aivado, M., Kobbe, G., Valk, P.J.M., Passegue, E., Libermann, T.A., Delwel, R. and Tenen, D.G.
Nature Genetics 38
(11): 1269-1277.
November 2006
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.
Steidl, U., Steidl, C., Ebralidze, A., Chapuy, B., Han, H.J., Will, B., Rosenbauer, F., Becker, A., Wagner, K., Koschmieder, S., Kobayashi, S., Costa, D.B., Schulz, T., OBrien, K.B., Verhaak, R.G.W., Delwel, R., Haase, D., Truemper, L., Krauter, J., Kohwi-Shigematsu, T., Griesinger, F. and Tenen, D.G.
Journal of Clinical Investigation 117
(9): 2611-2620.
4 September 2007
The hok mRNA family.
Steif, A. and Meyer, I.M.
RNA Biology 9
(12): 1399-1404.
1 December 2012
Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis.
Stein, U., Arlt, F., Smith, J., Sack, U., Herrmann, P., Walther, W., Lemm, M., Fichtner, I., Shoemaker, R.H. and Schlag, P.M.
Neoplasia 13
(2): 131-144.
February 2011
The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer.
Stein, U., Arlt, F., Walther, W., Smith, J., Waldman, T., Harris, E.D., Mertins, S.D., Heizmann, C.W., Allard, D., Birchmeier, W., Schlag, P.M. and Shoemaker, R.H.
Gastroenterology 131
(5): 1486-1500.
November 2006
YB-1 facilitates basal and 5-fluorouracil-inducible expression of the human major vault protein (MVP) gene.
Stein, U., Bergmann, S., Scheffer, G.L., Scheper, R.J., Royer, H.D., Schlag, P.M. and Walther, W.
Oncogene 24
(22): 3606-3618.
1 January 2005
Circulating MACC1 transcripts in colorectal cancer patient plasma predict metastasis and prognosis.
Stein, U., Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Schlag, P.M.
PLoS ONE 7
(11): e49249.
14 November 2012
Diagnostic and prognostic value of metastasis inducer S100A4 transcripts in plasma of colon, rectal, and gastric cancer patients.
Stein, U., Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Schlag, P.M.
Journal of Molecular Diagnostics 13
(2): 189-198.
March 2011
Impact of mutant beta-catenin on ABCB1 expression and therapy response in colon cancer cells.
Stein, U., Fleuter, C., Siegel, F., Smith, J., Kopacek, A., Scudiero, D.A., Hite, K.M., Schlag, P.M., Shoemaker, R.H. and Walther, W.
British Journal of Cancer 106
(8): 1395-1405.
10 April 2012
Reversal of ABC transporter-dependent multidrug resistance in cancer: A realistic option?
Stein, U. and Walther, W.
American Journal of Cancer 5
(5): 285-297.
September 2006
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Stein, U., Walther, W., Arlt, F., Schwabe, H., Smith, J., Fichtner, I., Birchmeier, W. and Schlag, P.M.
Nature Medicine 15
(1): 59-67.
January 2009
"Multidrug-Resistenz". Zellulaere Transportprobleme und ihre Konsequenzen ["Multidrug resistance". Cellular transport problems and their consequences].
Stein, U., Walther, W. and Schlag, P.M.
Paediatrische Praxis 68
: 11-19.
1 January 2006
"Multidrug-Resistenz". Zellulaere Transportprobleme und ihre Konsequenzen ["Multidrug resistance". Cellular transport problems and their consequences].
Stein, U., Walther, W. and Schlag, P.M.
Taegliche Praxis 46
(1): 125-133.
1 January 2005
Complete in vivo reversal of the multidrug resistance phenotype by jet-injection of anti-MDR1 short hairpin RNA-encoding plasmid DNA.
Stein, U., Walther, W., Stege, A., Kaszubiak, A., Fichtner, I. and Lage, H.
Molecular Therapy 16
(1): 178-186.
January 2008
Point mutations in the mdr1 promoter of human osteosarcomas are associated with in vitro responsiveness to multidrug resistance relevated drugs.
Stein, U., Walther, W. and Wunderlich, V.
European Journal of Cancer 30A
(10): 1541-1545.
1994
Expression of the mdr1 gene in bone and soft tissue sarcomas of adult patients.
Stein, U., Wunderlich, V., Haensch, W. and Schmidt-Peter, P.
European Journal of Cancer 29A
(14): 1979-1981.
1993
Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting.
Steinbrecht, D., Minia, I., Milek, M., Meisig, J., Blüthgen, N. and Landthaler, M.
Molecular Systems Biology 20
(12): 1346-1371.
2 December 2024
HCoV- and SARS-CoV-2 cross-reactive T cells in CVID patients.
Steiner, S., Sotzny, F., Bauer, S., Na, I.K., Schmueck-Henneresse, M., Corman, V.M., Schwarz, T., Drosten, C., Wendering, D.J., Behrends, U., Volk, H.D., Scheibenbogen, C. and Hanitsch, L.G.
Frontiers in Immunology 11
: 607918.
23 December 2020
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A., Moebs, M., Ullmann, R., Koechert, K., Kreher, S., Lamprecht, B., Anagnostopoulos, I., Hummel, M., Richter, J., Beyer, M., Janz, M., Klemke, C.D., Stein, H., Doerken, B., Sterry, W., Schrock, E., Mathas, S. and Assaf, C.
Journal of Experimental Medicine 208
(8): 1585-1593.
1 August 2011
Recombinant murine erythropoietin receptor expressed in avian erythroid progenitors mediates terminal erythroid differentiation in vitro.
Steinlein, P., Deiner, E., Leutz, A. and Beug, H.
Growth Factors 10
(1): 1-16.
1994
BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection.
Steinmetz, O.M., Panzer, U., Kneissler, U., Harendza, S., Lipp, M., Helmchen, U. and Stahl, R.A.K.
Kidney International 67
: 1616-1621.
1 January 2005
CopR binds and bends its target DNA: a footprinting and fluorescence resonance energy transfer study.
Steinmetzer, K., Behlke, J., Brantl, S. and Lorenz, M.
Nucleic Acids Research 30
(9): 2052-2060.
1 May 2002
Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets.
Stelljes, M., Strothotte, R., Pauels, H.G., Poremba, C., Milse, M., Specht, C., Albring, J., Bisping, G., Scheffold, C., Kammertoens, T., Oelmann, E., Silling, G., Berdel, W.E. and Kienast, J.
Blood 104
(4): 1210-1216.
1 January 2004
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl, U., Worm, U., Lalowski, M., Haenig, C., Brembeck, F.H., Goehler, H., Stroedicke, M., Zenkner, M., Schoenherr, A., Koeppen, S., Timm, J., Mintzlaff, S., Abraham, C., Bock, N., Kietzmann, S., Goedde, A., Toksoez, E., Droege, A., Krobitsch, S., Korn, B., Birchmeier, W., Lehrach, H. and Wanker, E.E.
Cell 122
(6): 957-968.
23 September 2005
Structurally related Arabidopsis ANGUSTIFOLIA is functionally distinct from the transcriptional corepressor CtBP.
Stern, M.D., Aihara, H., Cho, K.H., Kim, G.T., Horiguchi, G., Roccaro, G.A., Guevara, E., Sun, H.H., Negeri, D., Tsukaya, H. and Nibu, Y.
Development Genes and Evolution 217
(11-12): 759-769.
December 2007
A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity.
Stern, D., Meyer, T.C., Treindl, F., Mages, H.W., Krüger, M., Skiba, M., Krüger, J.P., Zobel, C.M., Schreiner, M., Grossegesse, M., Rinner, T., Peine, C., Stoliaroff-Pépin, A., Harder, T., Hofmann, N., Michel, J., Nitsche, A., Stahlberg, S., Kneuer, A., Sandoni, A., Kubisch, U., Schlaud, M., Mankertz, A., Schwarz, T., Corman, V.M., Müller, M.A., Drosten, C., de la Rosa, K., Schaade, L., Dorner, M.B. and Dorner, B.G.
Scientific Reports 13
(1): 21846.
9 December 2023
Structure of the chicken myelomonocytic growth factor gene and specific activation of its promoter in avian myelomonocytic cells by protein kinases.
Sterneck, E., Blattner, C., Graf, T. and Leutz, A.
Molecular and Cellular Biology 12
(4): 1728-1735.
April 1992
Autocrine growth induced by kinase type oncogenes in myeloid cells requires AP-1 and NF-M, a myeloid specific, C/EBP-like factor.
Sterneck, E., Mueller, C., Katz, S. and Leutz, A.
EMBO Journal 11
(1): 115-126.
January 1992
Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.
Stilgenbauer, S., Schnaiter, A., Paschka, P., Zenz, T., Rossi, M., Döhner, K., Bühler, A., Böttcher, S., Ritgen, M., Kneba, M., Winkler, D., Tausch, E., Hoth, P., Edelmann, J., Mertens, D., Bullinger, L., Bergmann, M., Kless, S., Mack, S., Jäger, U., Patten, N., Wu, L., Wenger, M.K., Fingerle-Rowson, G., Lichter, P., Cazzola, M., Wendtner, C.M., Fink, A.M., Fischer, K., Busch, R., Hallek, M. and Döhner, H.
Blood 123
(21): 3247-3254.
22 May 2014
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IκB kinase activation.
Stilmann, M., Hinz, M., Coel Arslan, S., Zimmer, A., Schreiber, V. and Scheidereit, C.
Molecular Cell 36
(3): 365-378.
13 November 2009
Lymphoid to myeloid cell trans-differentiation is determined by C/EBPβ structure and post-translational modifications.
Stoilova, B., Kowenz-Leutz, E., Scheller, M. and Leutz, A.
PLoS ONE 8
(6): e65169.
5 June 2013
Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell lines.
Stolze, B., Reinhart, S., Bullinger, L., Fröhling, S. and Scholl, C.
Scientific Reports 5
: 8535.
23 February 2015
NF-κB activation protects oligodendrocytes against inflammation.
Stone, S., Jamison, S., Yue, Y., Durose, W., Schmidt-Ullrich, R. and Lin, W.
Journal of Neuroscience 37
(38): 9332-9344.
20 September 2017
IFN-γ regulates CD8(+) memory T cell differentiation and survival in response to weak, but not strong, TCR signals.
Stoycheva, D., Deiser, K., Stärck, L., Nishanth, G., Schlüter, D., Uckert, W. and Schüler, T.
Journal of Immunology 194
(2): 553-559.
15 January 2015
Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels.
Strasen, J., Sarma, U., Jentsch, M., Bohn, S., Sheng, C., Horbelt, D., Knaus, P., Legewie, S. and Loewer, A.
Molecular Systems Biology 14
(1): e7733.
25 January 2018
Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Straube, J., Eifert, T., Vu, T., Janardhanan, Y., Haldar, R., von Eyss, B., Cooper, L., Bruedigam, C., Ling, V.Y., Cooper, E., Patch, A.M., Bullinger, L., Schnoeder, T.M., Bywater, M., Heidel, F.H. and Lane, S.W.
Leukemia 37
(4): 741-750.
April 2023
Prevalence of primary hyperaldosteronism in moderate to severe hypertension in the Central Europe region.
Strauch, B., Zelinka, T., Hampf, M., Bernhardt, R. and Widimsky, J.
Journal of Human Hypertension 17
(5): 349-352.
May 2003
SMITH: spatially constrained stochastic model for simulation of intra-tumour heterogeneity.
Streck, A., Kaufmann, T.L. and Schwarz, R.F.
Bioinformatics 39
(3): btad102.
March 2023
Sarcoma patients admitted to the intensive care unit (ICU): predictive relevance of common sepsis and performance parameters.
Striefler, J.K., Binder, P.T., Brandes, F., Rau, D., Wittenberg, S., Kaul, D., Roohani, S., Jarosch, A., Schäfer, F.M., Öllinger, R., Märdian, S., Bullinger, L., Eckardt, K.U., Kruse, J. and Flörcken, A.
Cancer Management and Research 15
: 321-334.
27 March 2023
Combination therapy with Olaratumab/doxorubicin in advanced or metastatic soft tissue sarcoma -a single-Centre experience.
Striefler, J.K., Brandes, F., Baur, A., Pfitzner, B.M., Kaul, D., Rau, D., Dörr, A., Schmiester, M., Koulaxouzidis, G., Bullinger, L., Märdian, S. and Flörcken, A.
BMC Cancer 20
(1): 68.
29 January 2020
Comorbidities rather than older age define outcome in adult patients with tumors of the Ewing sarcoma family.
Striefler, J.K., Schmiester, M., Brandes, F., Dörr, A., Pahl, S., Kaul, D., Rau, D., Dobrindt, E.M., Koulaxouzidis, G., Bullinger, L., Märdian, S. and Flörcken, A.
Cancer Medicine 11
(17): 3213-3225.
September 2022
Armadillo motifs involved in vesicular transport.
Striegl, H., Andrade-Navarro, M.A. and Heinemann, U.
PLoS ONE 5
(2): e8991.
1 February 2010
Unusual armadillo fold in the human general vesicular transport factor p115.
Striegl, H., Roske, Y., Kuemmel, D. and Heinemann, U.
PLoS ONE 4
(2): e4656.
27 February 2009
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke, M., Bounab, Y., Strempel, N., Klockmeier, K., Yigit, S., Friedrich, R.P., Chaurasia, G., Li, S., Hesse, F., Riechers, S.P., Russ, J., Nicoletti, C., Boeddrich, A., Wiglenda, T., Haenig, C., Schnoegl, S., Fournier, D., Graham, R.K., Hayden, M.R., Sigrist, S., Bates, G.P., Priller, J., Andrade-Navarro, M.A., Futschik, M.E. and Wanker, E.E.
Genome Research 25
(5): 701-713.
May 2015
MCT1 is a predictive marker for lenalidomide maintenance therapy in multiple myeloma.
Stroh, J., Seckinger, A., Heider, M., Rudelius, M., Eichner, R., Schick, M., Slawska, J., Emde, M., Salwender, H., Bertsch, U., Goldschmidt, H., Weisel, K.C., Scheid, C., Keller, U., Hose, D. and Bassermann, F.
Blood Advances 6
(2): 515-520.
25 January 2022
Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) gene expression via MEK/ERK-dependent activation of Sp1 and Sp3.
Strowski, M.Z., Cramer, T., Schaefer, G., Juettner, S., Walduck, A., Schipani, E., Kemmner, W., Wessler, S., Wunder, C., Weber, M., Meyer, T.F., Wiedenmann, B., Joens, T., Naumann, M. and Hoecker, M.
FASEB Journal 18
(1): 218-220.
January 2004
Therapy adherence after interdisciplinary tumour board discussion is associated with improved outcome in soft tissue sarcoma: a Charité Comprehensive Cancer Centre analysis.
Strönisch, A., Rau, D., Wittenberg, S., Kaul, D., Koulaxouzidis, G., Öllinger, R., von Laffert, M., Jarosch, A., Schäfer, F., Keilholz, U., Bullinger, L., Märdian, S., Striefler, J. and Flörcken, A.
International Journal of Cancer
16 October 2024
(In Press)
Selective pharmacologic activation of the p53-dependent pathway as a therapeutic strategy for hematologic malignancies.
Stuehmer, T. and Bargou, R.C.
Cell Cycle 5
: 39-42.
1 January 2006
Non-genotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.
Stuehmer, T., Chatterjee, M., Hildebrandt, M., Herrmann, P., Gollasch, H., Gerecke, C., Theurich, S., Cigliano, L., Manz, R.A., Daniel, P.T., Bommert, K., Vassilev, L.T. and Bargou, R.C.
Blood 106
: 3609-3617.
4 August 2005
Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy.
Sturm, I., Bosanquet, A.G., Hermann, S., Guener, D., Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 10
(4): 477-484.
1 April 2003
In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis.
Sturm, I., Bosanquet, A.G., Hummel, M., Doerken, B. and Daniel, P.T.
BMC Cancer 5
: 105.
18 August 2005
Silencing of APAF-1 in B-CLL results in poor prognosis in the case of concomitant p53 mutation.
Sturm, I., Bosanquet, A.G., Radetzki, S., Hummel, M., Doerken, B. and Daniel, P.T.
International Journal of Cancer 118
: 2329-2336.
1 May 2006
Panhypopituitarism in a patient with breast cancer.
Sturm, I., Kirschke, S., Krahl, D. and Doerken, B.
Onkologie 27
: 480-482.
1 January 2004
Succesful long-term monotherapy with rituximab in a chemotherapy-refractory patient with chronic B-CLL: a case report.
Sturm, I., Oertel, J., Oertel, S., Westermann, J. and Pezzutto, A.
Journal of Medical Case Reports 2
(1): 275.
14 August 2008
Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy.
Sturm, I., Rau, B., Schlag, P.M., Wust, P., Hildebrandt, B., Riess, H., Hauptmann, S., Doerken, B. and Daniel, P.T.
BMC Cancer 6
: 124.
10 May 2006
Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Sturm, I., Stephan, C., Gillissen, B., Siebert, R., Janz, M., Radetzki, S., Jung, K., Loening, S., Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 13
: 619-627.
April 2006
Comprehensive small RNA-Seq of adeno-associated virus (AAV)-infected human cells detects patterns of novel, non-coding AAV RNAs in the absence of cellular miRNA regulation.
Stutika, C., Mietzsch, M., Gogol-Doering, A., Weger, S., Sohn, M., Chen, W. and Heilbronn, R.
PLoS ONE 11
(9): e0161454.
9 September 2016
Immunotherapy with TCR-redirected T cells: comparison of TCR-transduced and TCR-engineered hematopoietic stem cell-derived T cells.
Stärck, L., Popp, K., Pircher, H. and Uckert, W.
Journal of Immunology 192
(1): 206-213.
1 January 2014
Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity.
Stöber, M.C., Chamorro González, R., Brückner, L., Conrad, T., Wittstruck, N., Szymansky, A., Eggert, A., Schulte, J.H., Koche, R.P., Henssen, A.G., Schwarz, R.F. and Haase, K.
Cell Reports 43
(9): 114711.
24 September 2024
Therapy for recurrent high-grade gliomas: results of a prospective multicenter study on health-related quality of life.
Stöckelmaier, L., Renovanz, M., König, J., Nickel, K., Hickmann, A.K., Mayer-Steinacker, R., Nadji-Ohl, M., Ganslandt, O., Bullinger, L., Wirtz, C.R. and Coburger, J.
World Neurosurgery 102
: 383-399.
June 2017
Molecular subtyping of head and neck cancer - Clinical applicability and correlations with morphological characteristics.
Stögbauer, F., Otto, R., Jöhrens, K., Tinhofer, I., Keilholz, U., Poremba, C., Keller, U., Leser, U., Weichert, W., Boxberg, M. and Klinghammer, K.
Oral Oncology 149
: 106678.
February 2024
WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Su, F., Overholtzer, M., Besser, D. and Levine, A.J.
Genes & Development 16
(1): 46-57.
2002
Association of human leukocyte antigen haplotypes with posttransplant lymphoproliferative disease after solid organ transplantation.
Subklewe, M., Marquis, R., Choquet, S., Leblond, V., Garnier, J.L., Hetzer, R., Swinnen, L.J., Oertel, S., Papp-Vary, M., Gonzalez-Barca, E., Hepkema, B.G., Schoenemann, C., May, J., Pezzutto, A. and Riess, H.
Transplantation 82
(8): 1093-1100.
27 October 2006
Dendritic cell maturation stage determines susceptibility to the proteasome inhibitor bortezomib.
Subklewe, M., Sebelin-Wulf, K., Beier, C., Lietz, A., Mathas, S., Doerken, B. and Pezzutto, A.
Human Immunology 68
(3): 147-155.
March 2007
Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
Subramanian, S., Busch, C.J.L., Molawi, K., Geirsdottir, L., Maurizio, J., Vargas Aguilar, S., Belahbib, H., Gimenez, G., Yuda, R.A.A., Burkon, M., Favret, J., Gholamhosseinian Najjar, S., de Laval, B., Kandalla, P.K., Sarrazin, S., Alexopoulou, L. and Sieweke, M.H.
Nature Immunology 23
(3): 458-468.
March 2022
Televideo-Tumorkonferenz: Schnittstelle fuer eine optimierte medizinische Versorgung und Dokumentation.
Suchy, B.R., Blanke, M., Ulmer, C. and Schlag, P.M.
Forum 18
: 12-14.
1 January 2003
Inhibiting lysine demethylase 1A improves L1CAM-specific CAR T cell therapy by unleashing antigen-independent killing via the FAS-FASL axis.
Sulejmani, O., Grunewald, L., Andersch, L., Schwiebert, S., Klaus, A., Winkler, A., Astrahantseff, K., Eggert, A., Henssen, A.G., Schulte, J.H., Anders, K. and Künkele, A.
Cancers 13
(21): 5489.
31 October 2021
Human-specific tandem repeat expansion and differential gene expression during primate evolution.
Sulovari, A., Li, R., Audano, P.A., Porubsky, D., Vollger, M.R., Logsdon, G.A., Warren, W.C., Pollen, A.A., Chaisson, M.J.P. and Eichler, E.E.
Proceedings of the National Academy of Sciences of the United States of America 116
(46): 23243-23253.
12 November 2019
VH replacement in primary immunoglobulin repertoire diversification.
Sun, A., Novobrantseva, T.I., Coffre, M., Hewitt, S.L., Jensen, K., Skok, J.A., Rajewsky, K. and Koralov, S.B.
Proceedings of the National Academy of Sciences of the United States of America 112
(5): E458-E466.
3 February 2015
The prognostic relevance of miR-212 expression with survival in cytogenetically and molecularly heterogeneous AML.
Sun, S.M., Rockova, V., Bullinger, L., Dijkstra, M.K., Döhner, H., Löwenberg, B. and Jongen-Lavrencic, M.
Leukemia 27
(1): 100-6.
January 2013
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Sun, G., Kropp, K.A., Kirchner, M., Plückebaum, N., Selich, A., Serrero, M., Dhingra, A., Cabrera, J.R., Ritter, B., Bauerfeind, R., Wyler, E., Landthaler, M., Schambach, A., Sodeik, B., Mertins, P. and Viejo-Borbolla, A.
mBio 15
(2): e0330823.
14 February 2024
Molecular simulations suggest a force-dependent mechanism of vinculin activation.
Sun, L., Noel, J.K., Levine, H. and Onuchic, J.N.
Biophysical Journal 113
(8): 1697-1710.
17 October 2017
Metabolic labeling of newly synthesized RNA with 4sU to in parallel assess RNA transcription and decay.
Sun, W. and Chen, W.
Methods in Molecular Biology 1720
: 25-34.
2018
Pervasive allele-specific regulation on RNA decay in hybrid mice.
Sun, W., Gao, Q., Schaefke, B., Hu, Y. and Chen, W.
Life Science Alliance 1
(2): e201800052.
May 2018
53BP1 supports immunoglobulin class switch recombination independently of its DNA double-strand break end protection function.
Sundaravinayagam, D., Rahjouei, A., Andreani, M., Tupiņa, D., Balasubramanian, S., Saha, T., Delgado-Benito, V., Coralluzzo, V., Daumke, O. and Di Virgilio, M.
Cell Reports 28
(6): 1389-1399.
6 August 2019
Stress-induced nuclear speckle reorganization is linked to activation of immediate early gene splicing.
Sung, H.M., Schott, J., Boss, P., Lehmann, J.A., Hardt, M.R., Lindner, D., Messens, J., Bogeski, I., Ohler, U. and Stoecklin, G.
Journal of Cell Biology 222
(12): e202111151.
4 December 2023
Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
Suratanee, A., Schaefer, M.H., Betts, M.J., Soons, Z., Mannsperger, H., Harder, N., Oswald, M., Gipp, M., Ramminger, E., Marcus, G., Männer, R., Rohr, K., Wanker, E., Russell, R.B., Andrade-Navarro, M.A., Eils, R. and König, R.
PLoS Computational Biology 10
(9): e1003814.
25 September 2014
Development and application of a DNA microarray-based yeast two-hybrid system.
Suter, B., Fontaine, J.F., Yildirimman, R., Raskó, T., Schaefer, M.H., Rasche, A., Porras, P., Vázquez-Álvarez, B.M., Russ, J., Rau, K., Foulle, R., Zenkner, M., Saar, K., Herwig, R., Andrade-Navarro, M.A. and Wanker, E.E.
Nucleic Acids Research 41
(3): 1496-507.
1 February 2013
Embryonic hair follicle fate change by augmented β-catenin through Shh and Bmp signaling.
Suzuki, K., Yamaguchi, Y., Villacorte, M., Mihara, K., Akiyama, M., Shimizu, H., Taketo, M.M., Nakagata, N., Tsukiyama, T., Yamaguchi, T.P., Birchmeier, W., Kato, S. and Yamada, G.
Development 136
(3): 367-372.
February 2009
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
Swan, A.L., Schütt, C., Rozman, J., Del Mar Muñiz Moreno, M., Brandmaier, S., Simon, M., Leuchtenberger, S., Griffiths, M., Brommage, R., Keskivali-Bond, P., Grallert, H., Werner, T., Teperino, R., Becker, L., Miller, G., Moshiri, A., Seavitt, J.R., Cissell, D.D., Meehan, T.F., Acar, E.F., Lelliott, C.J., Flenniken, A.M., Champy, M.F., Sorg, T., Ayadi, A., Braun, R.E., Cater, H., Dickinson, M.E., Flicek, P., Gallegos, J., Ghirardello, E.J., Heaney, J.D., Jacquot, S., Lally, C., Logan, J.G., Teboul, L., Mason, J., Spielmann, N., McKerlie, C., Murray, S.A., Nutter, L.M.J., Odfalk, K.F., Parkinson, H., Prochazka, J., Reynolds, C.L., Selloum, M., Spoutil, F., Svenson, K.L., Vales, T.S., Wells, S.E., White, J.K., Sedlacek, R., Wurst, W., Lloyd, K.K.C., Croucher, P.I., Fuchs, H., Williams, G.R., Bassett, D., Gailus-Durner, V., Herault, Y., Mallon, A.M., Brown, S.D.M., Mayer-Kuckuk, P. and Hrabe de Angelis, M.
PLoS Genetics 16
(12): e1009190.
28 December 2020
Effects of tamoxifen, droloxifene and 17beta-estradiol on Rauscher mouse leukemogenesis.
Sydow, G. and Wunderlich, V.
Cancer Letters 82
(1): 89-94.
15 July 1994
Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients.
Szasz, A.M., Lanczky, A., Nagy, A., Foerster, S., Hark, K., Green, J.E., Boussioutas, A., Busuttil, R., Szabo, A. and Gyorffy, B.
Oncotarget 7
(31): 49322-49333.
2 August 2016
Towards a deeper annotation of human lncRNAs.
Szcześniak, M.W., Wanowska, E., Mukherjee, N., Ohler, U. and Makałowska, I.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1863
(4): 194385.
April 2020
Neuroblastoma risk assessment and treatment stratification with hybrid capture-based panel sequencing.
Szymansky, A., Kruetzfeldt, L.M., Heukamp, L.C., Hertwig, F., Theissen, J., Deubzer, H.E., Willing, E.M., Menon, R., Fuchs, S., Thole, T., Schulte, S., Schmelz, K., Künkele, A., Lang, P., Fuchs, J., Eggert, A., Eckert, C., Fischer, M., Henssen, A.G., Rodriguez-Fos, E. and Schulte, J.H.
Journal of Personalized Medicine 11
(8): 691.
August 2021
A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo.
Szyska, M., Herda, S., Althoff, S., Heimann, A., Russ, J., D'Abundo, D., Dang, T.M., Durieux, I., Dörken, B., Blankenstein, T. and Na, I.K.
Cancer Immunology Research 6
(1): 110-120.
January 2018
V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta-catenin is not required for the shift.
Takeda, H., Nagafuchi, A., Yonemura, S., Tsukita, S., Behrens, J., Birchmeier, W. and Tsukita, S.
Journal of Cell Biology 131
(6 Pt. 2): 1839-1847.
December 1995
Insertional mutagenesis of the mouse germline with Sleeping Beauty transposition.
Takeda, J., Izsvak, Z. and Ivics, Z.
Methods in Molecular Biology 435
: 109-125.
2008
The landscape of genetic aberrations in myxofibrosarcoma.
Takeuchi, Y., Yoshida, K., Halik, A., Kunitz, A., Suzuki, H., Kakiuchi, N., Shiozawa, Y., Yokoyama, A., Inoue, Y., Hirano, T., Yoshizato, T., Aoki, K., Fujii, Y., Nannya, Y., Makishima, H., Pfitzner, B.M., Bullinger, L., Hirata, M., Jinnouchi, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Okamoto, T., Haga, H., Ogawa, S. and Damm, F.
International Journal of Cancer 151
(4): 565-577.
15 August 2022
Role of Epiprofin, a zinc-finger transcription factor, in limb development.
Talamillo, A., Delgado, I., Nakamura, T., de-Vega, S., Yoshitomi, Y., Unda, F., Birchmeier, W., Yamada, Y. and Ros, M.A.
Developmental Biology 337
(2): 363-374.
15 January 2010
Small molecule screening in zebrafish: swimming in potential drug therapies.
Tamplin, O.J., White, R.M., Jing, L., Kaufman, C.K., Lacadie, S.A., Li, P., Taylor, A.M. and Zon, L.I.
Wiley Interdisciplinary Reviews: Developmental Biology 1
(3): 459-468.
May 2012
Concomitant cytotoxic effector differentiation of CD4(+) and CD8(+) T cells in response to EBV-Infected B cells.
Tamura, Y., Yamane, K., Kawano, Y., Bullinger, L., Wirtz, T., Weber, T., Sander, S., Ohki, S., Kitajima, Y., Okada, S., Rajewsky, K. and Yasuda, T.
Cancers 14
(17): 4118.
25 August 2022
Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer.
Tan, W.L., Bhattacharya, B., Loh, M., Balasubramanian, I., Akram, M., Dong, D., Wong, L., Thakkar, B., Salto-Tellez, M., Soo, R.A., Fichtner, I., Iacopetta, B. and Soong, R.
Cancer Biology & Therapy 11
(6): 599-608.
15 March 2011
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
Tan, J., Pieper, K., Piccoli, L., Abdi, A., Foglierini, M., Geiger, R., Tully, C.M., Jarrossay, D., Ndungu, F.M., Wambua, J., Bejon, P., Silacci Fregni, C., Fernandez-Rodriguez, B., Barbieri, S., Bianchi, S., Marsh, K., Thathy, V., Corti, D., Sallusto, F., Bull, P. and Lanzavecchia, A.
Nature 529
(7584): 105-109.
7 January 2016
Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983.
Tanis, E., Julie, C., Emile, J.F., Mauer, M., Nordlinger, B., Aust, D., Roth, A., Lutz, M.P., Gruenberger, T., Wrba, F., Sorbye, H., Bechstein, W., Schlag, P., Fisseler, A. and Ruers, T.
European Journal of Cancer 51
(17): 2708-2717.
November 2015
Peritoneales Mesotheliom – ein seltener Tumor der Bauchhoehle [Peritoneal mesothelioma - rare abdominal tumors].
Tannapfel, A., Bruecher, B. and Schlag, P.M.
Onkologe 15
(3): 250-260.
March 2009
Aminophospholipids have no access to the luminal side of the biliary canaliculus - Implications for the specific lipid composition of the bile fluid.
Tannert, A., Wuestner, D., Bechstein, J., Mueller, P., Devaux, P.F. and Herrmann, A.
Journal of Biological Chemistry 278
(42): 40631-40639.
17 October 2003
The autonomy axiom and the cloning of humans.
Tannert, C.
Human Reproduction and Genetic Ethics 13
(1): 4-7.
2007
Der Schritt zum Menschen. Warum es einen Unterschied macht, ob Zellen oder Kinder geklont werden.
Tannert, C.
Tagesspiegel
: 25.
15 December 2005
Biologische und theologische Anmerkungen zum deutschen Ethik-Diskurs zur Biomedizin.
Tannert, C.
Zeitschrift fuer Biopolitik 2
(3): 185-190.
2003
A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional.
Tardiff, D.F., Lacadie, S.A. and Rosbash, M.
Molecular Cell 24
(6): 917-929.
28 December 2006
miR-184 regulates pancreatic β-cell function according to glucose metabolism.
Tattikota, S.G., Rathjen, T., Hausser, J., Khedkar, A., Kabra, U.D., Pandey, V.K., Sury, M.D., Wessels, H.H., Mollet, I.G., Eliasson, L., Selbach, M., Zinzen, R.P., Zavolan, M., Kadener, S., Tschöp, M., Jastroch, M., Friedländer, M.R. and Poy, M.N.
Journal of Biological Chemistry 290
(33): 20284-20294.
14 August 2015
Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.
Tausch, E., Beck, P., Schlenk, R.F., Jebaraj, B.M.C., Dolnik, A., Yosifov, D.Y., Hillmen, P., Offner, F., Janssens, A., Babu, K.G., Grosicki, S., Mayer, J., Panagiotidis, P., McKeown, A., Gupta, I.V., Skorupa, A., Pallaud, C., Bullinger, L., Mertens, D., Döhner, H. and Stilgenbauer, S.
Haematologica 105
(10): 2440-2447.
October 2020
Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.
Tausch, E., Schneider, C., Robrecht, S., Zhang, C., Dolnik, A., Bloehdorn, J., Bahlo, J., Al-Sawaf, O., Ritgen, M., Fink, A.M., Eichhorst, B., Kreuzer, K.A., Tandon, M., Humphrey, K., Jiang, Y., Schary, W., Bullinger, L., Mertens, D., Lurà, M.P., Kneba, M., Döhner, H., Fischer, K., Hallek, M. and Stilgenbauer, S.
Blood 135
(26): 2402-2412.
25 June 2020
Disease evolution and outcomes in familial AML with germline CEBPA mutations.
Tawana, K., Wang, J., Renneville, A., Bödör, C., Hills, R., Loveday, C., Savic, A., Van Delft, F.W., Treleaven, J., Georgiades, P., Uglow, E., Asou, N., Uike, N., Debeljak, M., Jazbec, J., Ancliff, P., Gale, R., Thomas, X., Mialou, V., Döhner, K., Bullinger, L., Mueller, B., Pabst, T., Stelljes, M., Schlegelberger, B., Wozniak, E., Iqbal, S., Okosun, J., Araf, S., Frank, A.K., Lauridsen, F.B., Porse, B., Nerlov, C., Owen, C., Dokal, I., Gribben, J., Smith, M., Preudhomme, C., Chelala, C., Cavenagh, J. and Fitzgibbon, J.
Blood 126
(10): 1214-1223.
3 September 2015
ER-Golgi traffic is a prerequisite for efficient ER degradation.
Taxis, C., Vogel, F. and Wolf, D.H.
Molecular Biology of the Cell 13
(6): 1806-1818.
1 June 2002
Arabidopsis uses a molecular grounding mechanism and a biophysical circuit breaker to limit floral abscission signaling.
Taylor, I.W., Patharkar, O.R., Mijar, M., Hsu, C.W., Baer, J., Niederhuth, C.E., Ohler, U., Benfey, P.N. and Walker, J.C.
Proceedings of the National Academy of Sciences of the United States of America 121
(44): e2405806121.
29 October 2024
Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi, Y., Arango-Ossa, J.E., Zhou, Y., Bernard, E., Thomas, I., Gilkes, A., Freeman, S., Pradat, Y., Johnson, S.J., Hills, R., Dillon, R., Levine, M.F., Leongamornlert, D., Butler, A., Ganser, A., Bullinger, L., Döhner, K., Ottmann, O., Adams, R., Döhner, H., Campbell, P.J., Burnett, A.K., Dennis, M., Russell, N.H., Devlin, S.M., Huntly, B.J.P. and Papaemmanuil, E.
Nature Communications 13
(1): 4622.
8 August 2022
Tetrameric oligomerization of I kappa B kinase gamma (IKK gamma) is obligatory for IKK complex activity and NF-kappa B activation.
Tegethoff, S., Behlke, J. and Scheidereit, C.
Molecular and Cellular Biology 23
(6): 2029-2041.
March 2003
Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.
Teixeira Alves, L.G., Baumgardt, M., Langner, C., Fischer, M., Maria Adler, J., Bushe, J., Firsching, T.C., Mastrobuoni, G., Grobe, J., Hoenzke, K., Kempa, S., Gruber, A.D., Hocke, A.C., Trimpert, J., Wyler, E. and Landthaler, M.
BMJ Open Respiratory Research 11
(1)
29 February 2024
A fucoidan plant drink reduces Helicobacter pylori load in the stomach: a real-world study.
Teng, Q.L., Sui, S.J., Zhu, Z., Gao, Q., Ge, H., Wang, K.Q., Lino-Silva, L.S., Sigal, M., White, J.R., Peng, Q.H. and Wei, Y.Z.
Translational Gastroenterology and Hepatology 8
: 34-34.
30 October 2023
A modified EBMT risk score and the hematopoietic cell transplantation-specific comorbidity index for pre-transplant risk assessment in adult acute lymphoblastic leukemia.
Terwey, T.H., Hemmati, P.G., Martus, P., Dietz, E., Vuong, L.G., Massenkeil, G., Doerken, B. and Arnold, R.
Haematologica 95
(5): 810-818.
May 2010
Comparison of chimerism and minimal residual disease monitoring for relapse prediction after allogeneic stem cell transplantation for adult acute lymphoblastic leukemia.
Terwey, T.H., Hemmati, P.G., Nagy, M., Pfeifer, H., Goekbuget, N., Brueggemann, M., Le Duc, T.M., le Coutre, P., Doerken, B. and Arnold, R.
Biology of Blood and Marrow Transplantation 20
(10): 1522-1529.
October 2014
NIH-defined graft-versus-host disease and evidence for a potent graft-versus-leukemia effect in patients with acute lymphoblastic leukemia.
Terwey, T.H., Le Duc, T.M., Hemmati, P.G., le Coutre, P., Nagy, M., Martus, P., Doerken, B. and Arnold, R.
Annals of Oncology 24
(5): 1363-1370.
May 2013
Allogeneic SCT in refractory or relapsed adult ALL is effective without prior reinduction chemotherapy.
Terwey, T.H., Massenkeil, G., Tamm, I., Hemmati, P.G., Neuburger, S., Martus, P., Doerken, B., Hoelzer, D. and Arnold, R.
Bone Marrow Transplantation 42
(12): 791-798.
December 2008
How perifosine affects liposome-encapsulated drug delivery across a cell barrier.
Testen, A, Podlipec, R, Mravljak, J, Orthmann, A, Sentjurc, M, Zeisig, R, Strancar, J and Koklic, T
Therapeutic Delivery 6
(4): 423-441.
April 2015
beta-catenin-dependent and -independent effects of deltaN-plakoglobin on epidermal growth and differentiation.
Teuliere, J., Faraldo, M.M., Shtutman, M., Birchmeier, W., Huelsken, J., Thiery, J.P. and Glukhova, M.A.
Molecular and Cellular Biology 24
(19): 8649-8661.
1 October 2004
CD28 co-stimulus achieves superior CAR T cell effector function against solid tumors than 4-1BB co-stimulus.
Textor, A., Grunewald, L., Anders, K., Klaus, A., Schwiebert, S., Winkler, A., Stecklum, M., Rolff, J., Henssen, A.G., Höpken, U.E., Eggert, A., Schulte, J.H., Jensen, M.C., Blankenstein, T. and Künkele, A.
Cancers 13
(5): 1050.
2 March 2021
Efficacy of CAR T-cell therapy in large tumors relies upon stromal targeting by IFNγ.
Textor, A., Listopad, J.J., Wührmann, L.L., Perez, C., Kruschinski, A., Chmielewski, M., Abken, H., Blankenstein, T. and Charo, J.
Cancer Research 74
(23): 6796-6805.
1 December 2014
Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Textor, A., Schmidt, K., Kloetzel, P.M., Weißbrich, B., Perez, C., Charo, J., Anders, K., Sidney, J., Sette, A., Schumacher, T.N.M., Keller, C., Busch, D.H., Seifert, U. and Blankenstein, T.
Journal of Experimental Medicine 213
(11): 2333-2348.
17 October 2016
ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope.
Textoris-Taube, K., Cammann, C., Henklein, P., Topfstedt, E., Ebstein, F., Henze, S., Liepe, J., Zhao, F., Schadendorf, D., Dahlmann, B., Uckert, W., Paschen, A., Mishto, M. and Seifert, U.
European Journal of Immunology 50
(2): 270-283.
February 2020
Identification of proteins and miRNAs that specifically bind an mRNA in vivo.
Theil, K., Imami, K. and Rajewsky, N.
Nature Communications 10
(1): 4205.
16 September 2019
Suppression of tumorigenicity of breast cancer cells by transfer of human chromosome 17 does not require transferred BRCA1 and p53 genes.
Theile, M., Hartmann, S., Scherthan, H., Arnold, W., Deppert, W., Frege, R., Glaab, F., Haensch, W. and Scherneck, S.
Oncogene 10
(3): 439-447.
2 February 1995
A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer.
Theile, M., Seitz, S., Arnold, W., Jandrig, B., Frege, R., Schlag, P.M., Haensch, W., Guski, H., Winzer, K.J., Barrett, J.C. and Scherneck, S.
Oncogene 13
(4): 677-685.
15 August 1996
Heterodimerization of AML1/ETO with CBFβ is required for leukemogenesis but not for myeloproliferation.
Thiel, V.N., Giaimo, B.D., Schwarz, P., Soller, K., Vas, V., Bartkuhn, M., Blätte, T.J., Döhner, K., Bullinger, L., Borggrefe, T., Geiger, H. and Oswald, F.
Leukemia 31
(11): 2491-2502.
November 2017
Discovery of a novel tumour metastasis-promoting gene, NVM-1.
Thiele, W., Novac, N., Mink, S., Schreiber, C., Plaumann, D., Fritzmann, J., Cremers, N., Rothley, M., Schwager, C., Regiert, T., Huber, P.E., Stein, U., Schlag, P., Moll, J., Abdollahi, A. and Sleeman, J.P.
Journal of Pathology 225
(1): 96-105.
September 2011
Enhanced tumorigenicity of fibroblasts transformed with human herpesvirus 8 chemokine receptor vGPCR by successive passage in nude and immunocompetent mice.
Thirunarayanan, N., Cifire, F., Fichtner, I., Posner, S., Benga, J., Reiterer, P., Kremmer, E., Koelble, K. and Lipp, M.
Oncogene 26
(39): 5702-5712.
23 August 2007
Patient-specific modeling of diffuse large B-cell lymphoma.
Thobe, K., Konrath, F., Chapuy, B. and Wolf, J.
Biomedicines 9
(11): 1655.
10 November 2021
Evaluating uncertainty in signaling networks using logical modeling.
Thobe, K., Kuznia, C., Sers, C. and Siebert, H.
Frontiers in Physiology 9
: 1335.
October 2018
Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML.
Thol, F., Gabdoulline, R., Liebich, A., Klement, P., Schiller, J., Kandziora, C., Hambach, L., Stadler, M., Koenecke, C., Flintrop, M., Pankratz, M., Wichmann, M., Neziri, B., Büttner, K., Heida, B., Klesse, S., Chaturvedi, A., Kloos, A., Göhring, G., Schlegelberger, B., Gaidzik, V.I., Bullinger, L., Fiedler, W., Heim, A., Hamwi, I., Eder, M., Krauter, J., Schlenk, R.F., Paschka, P., Döhner, K., Döhner, H., Ganser, A. and Heuser, M.
Blood 132
(16): 1703-1713.
18 October 2018
Acute myeloid leukemia derived from lympho-myeloid clonal hematopoiesis.
Thol, F., Klesse, S., Köhler, L., Gabdoulline, R., Kloos, A., Liebich, A., Wichmann, M., Chaturvedi, A., Fabisch, J., Gaidzik, V.I., Paschka, P., Bullinger, L., Bug, G., Serve, H., Göhring, G., Schlegelberger, B., Lübbert, M., Kirchner, H., Wattad, M., Kraemer, D., Hertenstein, B., Heil, G., Fiedler, W., Krauter, J., Schlenk, R.F., Döhner, K., Döhner, H., Ganser, A. and Heuser, M.
Leukemia 31
(6): 1286-1295.
June 2017
Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole, T.M., Toedling, J., Sprüssel, A., Pfeil, S., Savelyeva, L., Capper, D., Messerschmidt, C., Beule, D., Groeneveld-Krentz, S., Eckert, C., Gambara, G., Henssen, A.G., Finkler, S., Schulte, J.H., Sieber, A., Bluethgen, N., Regenbrecht, C.R.A., Künkele, A., Lodrini, M., Eggert, A. and Deubzer, H.E.
International Journal of Cancer 146
(4): 1031-1041.
15 February 2020
Different roles of the human Orc6 protein in the replication initiation process.
Thomae, A.W., Baltin, J., Pich, D., Deutsch, M.J., Ravasz, M., Zeller, K., Gossen, M., Hammerschmidt, W. and Schepers, A.
Cellular and Molecular Life Sciences 68
(22): 3741-3756.
November 2011
RNF4-dependent oncogene activation by protein stabilization.
Thomas, J.J., Abed, M., Heuberger, J., Novak, R., Zohar, Y., Beltra-Lopez, A.P., Trausch-Azar, J.S., Ilagan, M.X.G., Benhamou, D., Dittmar, G., Kopan, R., Birchmeier, W., Schwartz, A.L. and Orian, A.
Cell Reports 16
(12): 3388-3400.
20 September 2016
Phosphosite analysis of the cytomegaloviral mRNA export factor pUL69 reveals serines with critical importance for recruitment of cellular proteins Pin1 and UAP56/URH49.
Thomas, M., Müller, R., Horn, G., Bogdanow, B., Imami, K., Milbradt, J., Steingruber, M., Marschall, M., Schilling, E.M., Fossen, T. and Stamminger, T.
Journal of Virology 94
(8): e02151-19.
31 March 2020
Dimer formation of a stabilized Gbeta1 variant. A structural and energetic analysis.
Thoms, S., Max, K.E., Wunderlich, M., Jacso, T., Lilie, H., Reif, B., Heinemann, U. and Schmid, F.X.
Journal of Molecular Biology 391
(5): 918-932.
4 September 2009
Genomic evolution and personalized therapy of an infantile fibrosarcoma harboring an NTRK oncogenic fusion.
Thorwarth, A., Haase, K., Röefzaad, C., Pajtler, K.W., Schramm, K., Hauptmann, K., Behnke, A., Vokuhl, C., Elgeti, T., Gratopp, A., Schulte, J.H., Scheer, M., Hernáiz Driever, P., Nysom, K., Eggert, A., Henssen, A.G. and Deubzer, H.E.
JCO Precision Oncology 6
: e2100283.
25 May 2022
Recurrent gastric adenocarcinoma with unusual metastatic localization and excellent response to docetaxel and 5-FU continuous infusion.
Thuss-Patience, P.C., Kretzschmar, A., Krenn, V., Doerken, B. and Reichardt, P.
Onkologie 26
(1): 63-65.
1 February 2003
Docetaxel and continuous-infusion fluorouracil versus epirubicin, cisplatin, and fluorouracil for advanced gastric adenocarcinoma: a randomized phase II study.
Thuss-Patience, P.C., Kretzschmar, A., Repp, M., Kingreen, D., Hennesser, D., Micheel, S., Pink, D., Scholz, C., Doerken, B. and Reichardt, P.
Journal of Clinical Oncology 23
: 494-501.
1 January 2005
Oxaliplatin and 5-fluorouracil for heavily pretreated metastatic breast cancer: a preliminary phase II study.
Thuss-Patience, P.C., von Minckwitz, G., Kretzschmar, A., Loibl, S., Schaller, G., Doerken, B. and Reichardt, P.
Anti-Cancer Drugs 14
(7): 549-553.
1 August 2003
A sensitive noninvasive method for monitoring successful liver-directed gene transfer of the low-density lipoprotein receptor in Watanabe hyperlipidemic rabbits in vivo.
Tietge, U.J.F., Cichon, G., Buettner, C., Genschel, J., Heeren, J., Gielow, P., Grewe, N., Dogar, M., Beisiegel, U., Manns, M.P., Lochs, H., Burchert, W. and Schmidt, H.H.J.
Gene Therapy 11
(7): 574-580.
April 2004
Small-molecule dual PLK1 and BRD4 inhibitors are active against preclinical models of pediatric solid tumors.
Timme, N., Han, Y., Liu, S., Yosief, H.O., García, H.D., Bei, Y., Klironomos, F., MacArthur, I.C., Szymansky, A., von Stebut, J., Bardinet, V., Dohna, C., Künkele, A., Rolff, J., Hundsdörfer, P., Lissat, A., Seifert, G., Eggert, A., Schulte, J.H., Zhang, W. and Henssen, A.G.
Translational Oncology 13
(2): 221-232.
February 2020
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation.
Tiniakou, I., Hsu, P.F., Lopez-Zepeda, L.S., Garipler, G., Esteva, E., Adams, N.M., Jang, G., Soni, C., Lau, C.M., Liu, F., Khodadadi-Jamayran, A., Rodrick, T.C., Jones, D., Tsirigos, A., Ohler, U., Bedford, M.T., Nimer, S.D., Kaartinen, V., Mazzoni, E.O. and Reizis, B.
Science Immunology 9
(94): eadi1023.
12 April 2024
N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma.
Tjaden, B., Baum, K., Marquardt, V., Simon, M., Trajkovic-Arsic, M., Kouril, T., Siebers, B., Lisec, J., Siveke, J.T., Schulte, J.H., Benary, U., Remke, M., Wolf, J. and Schramm, A.
Scientific Reports 10
(1): 7157.
28 April 2020
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage.
Toboso-Navasa, A., Gunawan, A., Morlino, G., Nakagawa, R., Taddei, A., Damry, D., Patel, Y., Chakravarty, P., Janz, M., Kassiotis, G., Brink, R., Eilers, M. and Calado, D.P.
Journal of Experimental Medicine 217
(7): e20191933.
6 July 2020
Conformational transitions and redox potential shifts of cytochrome P450 induced by immobilization.
Todorovic, S., Jung, C., Hildebrandt, P. and Murgida, D.H.
Journal of Biological Inorganic Chemistry 11
(1): 119-127.
January 2006
Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells.
Toews, K., Grunewald, L., Schwiebert, S., Klaus, A., Winkler, A., Ali, S., Zirngibl, F., Astrahantseff, K., Wagner, D.L., Henssen, A.G., Deubzer, H.E., Schulte, J.H., Ochsenreither, S., Eggert, A. and Künkele, A.
Molecular Carcinogenesis 59
(7): 724-273.
July 2020
LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.
Tomann, P., Paus, R., Millar, S.E., Scheidereit, C. and Schmidt-Ullrich, R.
Development 143
(9): 1512-1522.
1 May 2016
The Gfi-1B Proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation.
Tong, B., Grimes, H., Yang, T.Y., Bear, S., Qin, Z., Du, K., El-Deiry, W. and Tsichlis, P.
Molecular and Cellular Biology 18
(5): 2462-2473.
May 1998
Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
Torcal Garcia, G., Kowenz-Leutz, E., Tian, T.V, Klonizakis, A., Lerner, J., De Andres-Aguayo, L., Sapozhnikova, V., Berenguer, C., Carmona, M.P., Casadesus, M.V., Bulteau, R., Francesconi, M., Peiro, S., Mertins, P., Zaret, K., Leutz, A. and Graf, T.
eLife 12
: e83951.
27 June 2023
Long-term follow-up of the prospective randomized AATT study (autologous or allogeneic transplantation in patients with peripheral T-cell lymphoma).
Tournilhac, O., Altmann, B., Friedrichs, B., Bouabdallah, K., Leclerc, M., Cartron, G., Turlure, P., Reimer, P., Wagner-Drouet, E., Sanhes, L., Houot, R., Roussel, M., Kroschinsky, F., Dreger, P., Viardot, A., de Leval, L., Rosenwald, A., Gaulard, P., Wulf, G., Villate, A., Latiere, C., Elmaagacli, A., Glass, B., Poeschel, V., Damaj, G., Sibon, D., Durot, E., Bilger, K., Banos, A., Haenel, M., Dreyling, M., Keller, U., Tiab, M., Drenou, B., Cornillon, J., Nguyen, S., Robin, M., Nickelsen, M., Trümper, L., Lenz, G., Ziepert, M. and Schmitz, N.
Journal of Clinical Oncology 42
(32): 3788-3794.
10 November 2024
In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis.
Tran, N.T., Graf, R., Acevedo-Ochoa, E., Trombke, J., Weber, T., Sommermann, T., Salomon, C., Kühn, R., Rajewsky, K. and Chu, V.T.
Leukemia 38
(9): 2003-2015.
September 2024
Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors.
Tran, N.T., Bashir, S., Li, X., Rossius, J., Chu, V.T., Rajewsky, K. and Kühn, R.
Frontiers in Genetics 10
: 365.
30 April 2019
Precise CRISPR/Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells.
Tran, N.T., Danner, E., Li, X., Graf, R., Lebedin, M., de la Rosa, K., Kühn, R., Rajewsky, K. and Chu, V.T.
Science Advances 8
(22): eabm9106.
3 June 2022
CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia.
Tran, N.T., Graf, R., Wulf-Goldenberg, A., Stecklum, M., Strauß, G., Kühn, R., Kocks, C., Rajewsky, K. and Chu, V.T.
Molecular Therapy 28
(12): 2621-2634.
2 December 2020
Application of a spacer-nick gene-targeting approach to repair disease-causing mutations with increased safety.
Tran, N.T., Lebedin, M., Danner, E., Kühn, R., Rajewsky, K. and Chu, V.T.
Bio-protocol 13
(8): e4661.
20 April 2023
Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells.
Tran, N.T., Sommermann, T., Graf, R., Trombke, J., Pempe, J., Petsch, K., Kühn, R., Rajewsky, K. and Chu, V.T.
Cell Reports 28
(13): 3510-3522.
24 September 2019
Protocol for efficient CRISPR/Cas9/AAV-mediated homologous recombination in mouse hematopoietic stem and progenitor cells.
Tran, N.T., Trombke, J., Rajewsky, K. and Chu, V.T.
STAR Protocols 1
(1): 100028.
19 June 2020
Comparable CD8(+) T-cell responses to SARS-CoV-2 vaccination in single-cell transcriptomics of recently allogeneic transplanted patients and healthy individuals.
Tranter, Eva, Frentsch, Marco, Hütter-Krönke, Marie Luise, Vuong, Giang Lam, Busch, David, Loyal, Lucie, Henze, Larissa, Rosnev, Stanislav, Blau, Igor-Wolfgang, Thiel, Andreas, Beule, D., Bullinger, L., Obermayer, B. and Na, I.K.
Journal of Medical Virology 96
(3): e29539.
March 2024
Treatment of PTLD with rituximab and CHOP reduces the risk of renal graft impairment after reduction of immunosuppression.
Trappe, R., Hinrichs, C., Appel, U., Babel, N., Reinke, P., Neumayer, H.H., Budde, K., Dreyling, M., Duehrsen, U., Kliem, V., Schuettrumpf, S., Hauser, I.A., Mergenthaler, H.G., Schlattmann, P., Anagnostopoulos, I., Doerken, B. and Riess, H.
American Journal of Transplantation 9
(10): 2331-2337.
October 2009
Salvage chemotherapy for refractory and relapsed posttransplant lymphoproliferative disorders (PTLD) after treatment with single-agent rituximab.
Trappe, R., Riess, H., Babel, N., Hummel, M., Lehmkuhl, H., Jonas, S., Anagnostopoulos, I., Papp-Vary, M., Reinke, P., Hetzer, R., Doerken, B. and Oertel, S.
Transplantation 83
(7): 912-918.
15 April 2007
Salvage therapy for relapsed posttransplant lymphoproliferative disorders (PTLD) with a second progression of PTLD after upfront chemotherapy: the role of single-agent rituximab.
Trappe, R.U., Choquet, S., Reinke, P., Dreyling, M., Mergenthaler, H.G., Jaeger, U., Kebelmann-Betzing, C., Jonas, S., Lehmkuhl, H., Anagnostopoulos, I., Leblond, V., Hetzer, R., Doerken, B., Riess, H. and Oertel, S.
Transplantation 84
(12): 1708-1712.
27 December 2007
Effective use of high-dose chemotherapy and autologous stem cell rescue for relapsed adult Wilms' tumor and a novel alteration in intron 1 of the WT1 gene.
Trappe, R.U., Riess, H., Lippek, F., Plotkin, M., Schumacher, V., Royer-Pokora, B., Hildebrandt, B., Zuber, J., Mapara, M.Y., Oertel, S. and Doerken, B.
Journal of Pediatric Hematology Oncology 26
: 820-823.
1 January 2004
S100A4 is a strong negative prognostic marker and potential therapeutic target in adenocarcinoma of the stomach and esophagus.
Treese, C., Hartl, K., Pötzsch, M., Dahlmann, M., von Winterfeld, M., Berg, E., Hummel, M., Timm, L., Rau, B., Walther, W., Daum, S., Kobelt, D. and Stein, U.
Cells 11
(6): 1056.
21 March 2022
Inhibition of MACC1-induced metastasis in esophageal and gastric adenocarcinomas.
Treese, C., Werchan, J., von Winterfeld, M., Berg, E., Hummel, M., Timm, L., Rau, B., Daberkow, O., Walther, W., Daum, S., Kobelt, D. and Stein, U.
Cancers 14
(7): 1773.
31 March 2022
AI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor.
Trepte, P., Secker, C., Olivet, J., Blavier, J., Kostova, S., Maseko, S.B., Minia, I., Silva Ramos, E., Cassonnet, P., Golusik, S., Zenkner, M., Beetz, S., Liebich, M.J., Scharek, N., Schutz, A., Sperling, M., Lisurek, M., Wang, Y., Spirohn, K., Hao, T., Calderwood, M.A., Hill, D.E., Landthaler, M., Choi, S.G., Twizere, J.C., Vidal, M. and Wanker, E.E.
Molecular Systems Biology 20
(4): 428-457.
2 April 2024
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.
Triana, S., Vonficht, D., Jopp-Saile, L., Raffel, S., Lutz, R., Leonce, D., Antes, M., Hernández-Malmierca, P., Ordoñez-Rueda, D., Ramasz, B., Boch, T., Jann, J.C., Nowak, D., Hofmann, W.K., Müller-Tidow, C., Hübschmann, D., Alexandrov, T., Benes, V., Trumpp, A., Paulsen, M., Velten, L. and Haas, S.
Nature Immunology 22
(12): 1577-1589.
December 2021
Molecular structure of chromosomal proteins HMG-14 and HMG-17: definition of a transcriptional enhancement domain distinct from the nucleosomal binding domain.
Trieschmann, L., Postnikov, Y., Rieckers, A. and Bustin, M.
Molecular and Cellular Biology 15
(12): 6663-6669.
December 1995
Development of an intein-mediated split-Cas9 system for gene therapy.
Truong, D.J.J., Kühner, K., Kühn, R., Werfel, S., Engelhardt, S., Wurst, W. and Ortiz, O.
Nucleic Acids Research 43
(13): 6450-6458.
27 July 2015
Nrf2 regulates CD4(+) T cell-induced acute graft-versus-host disease in mice.
Tsai, J.J., Velardi, E., Shono, Y., Argyropoulos, K.V., Holland, A.M., Smith, O.M., Yim, N.L., Rao, U.K., Kreines, F.M., Lieberman, S.R., Young, L.F., Lazrak, A., Youssef, S., Fu, Y.Y., Liu, C., Lezcano, C., Murphy, G.F., Na, I.K., Jenq, R.R., Hanash, A.M., Dudakov, J.A. and van den Brink, M.R.M.
Blood 132
(26): 2763-2774.
27 December 2018
CORUM: the comprehensive resource of mammalian protein complexes-2022.
Tsitsiridis, G., Steinkamp, R., Giurgiu, M., Brauner, B., Fobo, G., Frishman, G., Montrone, C. and Ruepp, A.
Nucleic Acids Research 51
(D1): D539-D545.
6 January 2023
ShapeSorter: a fully probabilistic method for detecting conserved RNA structure features supported by SHAPE evidence.
Tsybulskyi, V. and Meyer, I.M.
Nucleic Acids Research 50
(15): e85.
26 August 2022
R-chie: a web server and R package for visualizing cis and trans RNA-RNA, RNA-DNA and DNA-DNA interactions.
Tsybulskyi, V., Mounir, M. and Meyer, I.M.
Nucleic Acids Research 48
(18): e105.
9 October 2020
e-RNA: a collection of web-servers for the prediction and visualisation of RNA secondary structure and their functional features.
Tsybulskyi, V., Semenchenko, E. and Meyer, I.M.
Nucleic Acids Research 51
(W1): W160-W167.
5 July 2023
High prevalence of immunoglobulin light chain gene aberrations as revealed by FISH in multiple myeloma and MGUS.
Tuerkmen, S., Binder, A., Gerlach, A., Niehage, S., Melissari, M.T., Inandiklioglu, N., Doerken, B. and Burmeister, T.
Genes Chromosomes & Cancer 53
(8): 650-656.
August 2014
TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation.
Tufan, A.B., Lazarow, K., Kolesnichenko, M., Sporbert, A., von Kries, J.P. and Scheidereit, C.
EMBO Journal 41
(21): e110372.
2 November 2022
Ablative Verfahren bei der operativen Behandlung maligner Knochentumoren [Ablative procedures in surgical treatment of malignant bone tumors].
Tunn, P., Delbrueck, H. and Schlag, P.M.
Orthopaede 32
(11): 955-964.
November 2003
Sentinel node biopsy in synovial sarcoma.
Tunn, P.U., Andreou, D., Illing, H., Fleige, B., Dresel, S. and Schlag, P.M.
European Journal of Surgical Oncology 34
(6): 704-707.
June 2008
Weichteilsakrome. Aktuelle multimodale Diagnostik als Basis einer differenzierten operativen Therapie [Soft tissue sarcoma. Differentiating surgery based on modern multidisciplinary diagnosis].
Tunn, P.U., Gebauer, B., Fritzmann, J., Huenerbein, M. and Schlag, P.M.
Chirurg 75
(12): 1165-1173.
11 September 2004
Bilaterales Fibulainterponat. Biologische Rekonstruktion nach Resektion primaer maligner Knochentumoren [Bilateral fibula graft. Biological reconstruction following resection of malignant bone tumors].
Tunn, P.U., Moesta, T.K. and Delbrueck, H.
Chirurg 77
: 919-925.
October 2006
Der Riesenzelltumor des Knochens : Eine Analyse von 87 Patienten [Giant cell tumor of bone. An evaluation of 87 patients].
Tunn, P.U. and Schlag, P.M.
Zeitschrift fuer Orthopaedie und Ihre Grenzgebiete 141
(6): 690-698.
November 2003
Osteosarcoma in children: long-term functional analysis.
Tunn, P.U., Schmidt-Peter, P., Pomraenke, D. and Hohenberger, P.
Clinical Orthopaedics and Related Research 421
: 212-217.
1 January 2004
Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal.
Turajlic, S., Xu, H., Litchfield, K., Rowan, A., Horswell, S., Chambers, T., O'Brien, T., Lopez, J.I., Watkins, T.B.K., Nicol, D., Stares, M., Challacombe, B., Hazell, S., Chandra, A., Mitchell, T.J., Au, L., Eichler-Jonsson, C., Jabbar, F., Soultati, A., Chowdhury, S., Rudman, S., Lynch, J., Fernando, A., Stamp, G., Nye, E., Stewart, A., Xing, W., Smith, J.C., Escudero, M., Huffman, A., Matthews, N., Elgar, G., Phillimore, B., Costa, M., Begum, S., Ward, S., Salm, M., Boeing, S., Fisher, R., Spain, L., Navas, C., Grönroos, E., Hobor, S., Sharma, S., Aurangzeb, I., Lall, S., Polson, A., Varia, M., Horsfield, C., Fotiadis, N., Pickering, L., Schwarz, R.F., Silva, B., Herrero, J., Luscombe, N.M., Jamal-Hanjani, M., Rosenthal, R., Birkbak, N.J., Wilson, G.A., Pipek, O., Ribli, D., Krzystanek, M., Csabai, I., Szallasi, Z., Gore, M., McGranahan, N., Van Loo, P., Campbell, P., Larkin, J. and Swanton, C.
Cell 173
(3): 595-610.
19 April 2018
FIP200 claw domain binding to p62 promotes autophagosome formation at ubiquitin condensates.
Turco, E., Witt, M., Abert, C., Bock-Bierbaum, T., Su, M.Y., Trapannone, R., Sztacho, M., Danieli, A., Shi, X., Zaffagnini, G., Gamper, A., Schuschnig, M., Fracchiolla, D., Bernklau, D., Romanov, J., Hartl, M., Hurley, J.H., Daumke, O. and Martens, S.
Molecular Cell 74
(2): 330-346.
18 April 2019
Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization.
Turnbull, A.P., Kuemmel, D., Prinz, B., Holz, C., Schultchen, J., Lang, C., Niesen, F.H., Hofmann, K.P., Delbrueck, H., Behlke, J., Mueller, E.C., Jarosch, E., Sommer, T. and Heinemann, U.
EMBO Journal 24
(5): 875-884.
1 January 2005
B-cell-intrinsic STAT6 signaling controls germinal center formation.
Turqueti-Neves, A., Otte, M., da Costa, O.P., Höpken, U.E., Lipp, M., Buch, T. and Voehringer, D.
European Journal of Immunology 44
(7): 2130-2138.
July 2014
The discriminative ability of Prostate Health Index to detect prostate cancer is enhanced in combination with miR-222-3p.
Tölle, A., Jung, K., Friedersdorff, F., Maxeiner, A., Lein, M., Fendler, A. and Stephan, C.
Cancer Biomarkers 30
(4): 381-393.
9 April 2021
Plasmapheresis effectively abrogates severe liver toxicity of pegaspargase in a patient with acute lymphoblastic leukemia.
Tölle, M., Gökbuget, N., Habringer, S., Keller, U. and Schwartz, S.
Annals of Hematology 103
(8): 3269-3271.
August 2024
Detection and validation of circular DNA fragments using nanopore sequencing.
Tüns, A.I., Hartmann, T., Magin, S., Chamorro González, R., Henssen, A.G., Rahmann, S., Schramm, A. and Köster, J.
Frontiers in Genetics 13
: 867018.
30 May 2022
Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4.
Uckelmann, H., Blaszkiewicz, S., Nicolae, C., Haas, S., Schnell, A., Wurzer, S., Wagener, R., Aszodi, A. and Essers, M.A.G.
Journal of Experimental Medicine 213
(10): 1961-1971.
19 September 2016
Therapeutic targeting of preleukemia cells in a mouse model of mutant acute myeloid leukemia.
Uckelmann, H.J., Kim, S.M., Wong, E.M., Hatton, C., Giovinazzo, H., Gadrey, J.Y., Krivtsov, A.V., Rücker, F.G., Döhner, K., McGeehan, G.M., Levine, R.L., Bullinger, L., Vassiliou, G.S. and Armstrong, S.A.
Science 367
(6477): 586-590.
31 January 2020
Gentherapie mit T-Zellrezeptor modifizierten Zellen.
Uckert, W. and Blankenstein, T.
BioForum 28
(3): 27-30.
20 May 2005
TCR transgenes and transgene cassettes for TCR gene therapy: status in 2008.
Uckert, W. and Schumacher, T.N.
Cancer Immunology Immunotherapy 58
(5): 809-822.
May 2009
Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a negative tumors.
Ueberham, E., Glöckner, P., Göhler, C., Straub, B.K., Teupser, D., Schönig, K., Braeuning, A., Höhn, A.K., Jerchow, B., Birchmeier, W., Gaunitz, F., Arendt, T., Sansom, O., Gebhardt, R. and Ueberham, U.
Molecular Cancer Research 13
(2): 239-249.
February 2015
Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz.
Uehata, T., Yamada, S., Ori, D., Vandenbon, A., Giladi, A., Jelinski, A., Murakawa, Y., Watanabe, H., Takeuchi, K., Toratani, K., Mino, T., Kiryu, H., Standley, D.M., Tsujimura, T., Ikawa, T., Kondoh, G., Landthaler, M., Kawamoto, H., Rodewald, H.R., Amit, I., Yamamoto, R., Miyazaki, M. and Takeuchi, O.
Blood 143
(3): 243-257.
18 January 2024
CCR7 signals are essential for cortex-medulla migration of developing thymocytes.
Ueno, T., Saito, F., Gray, D.H.D., Kuse, S., Hieshima, K., Nakano, H., Kakiuchi, T., Lipp, M., Boyd, R.L. and Takahama, Y.
Journal of Experimental Medicine 200
(4): 493-505.
16 August 2004
Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.
Uhlitz, F., Bischoff, P., Peidli, S., Sieber, A., Trinks, A., Lüthen, M., Obermayer, B., Blanc, E., Ruchiy, Y., Sell, T., Mamlouk, S., Arsie, R., Wei, T.T., Klotz-Noack, K., Schwarz, R.F., Sawitzki, B., Kamphues, C., Beule, D., Landthaler, M., Sers, C., Horst, D., Blüthgen, N. and Morkel, M.
EMBO Molecular Medicine 13
(10): e14123.
7 October 2021
An immediate-late gene expression module decodes ERK signal duration.
Uhlitz, F., Sieber, A., Wyler, E., Fritsche-Guenther, R., Meisig, J., Landthaler, M., Klinger, B. and Blüthgen, N.
Molecular Systems Biology 13
(5): 928.
3 May 2017
Interrogation of human hematopoiesis at single-cell and single-variant resolution.
Ulirsch, J.C., Lareau, C.A., Bao, E.L., Ludwig, L.S., Guo, M.H., Benner, C., Satpathy, A.T., Kartha, V.K., Salem, R.M., Hirschhorn, J.N., Finucane, H.K., Aryee, M.J., Buenrostro, J.D. and Sankaran, V.G.
Nature Genetics 51
(4): 683-693.
April 2019
The genetic landscape of diamond-blackfan anemia.
Ulirsch, J.C., Verboon, J.M., Kazerounian, S., Guo, M.H., Yuan, D., Ludwig, L.S., Handsaker, R.E., Abdulhay, N.J., Fiorini, C., Genovese, G., Lim, E.T., Cheng, A., Cummings, B.B., Chao, K.R., Beggs, A.H., Genetti, C.A., Sieff, C.A., Newburger, P.E., Niewiadomska, E., Matysiak, M., Vlachos, A., Lipton, J.M., Atsidaftos, E., Glader, B., Narla, A., Gleizes, P.E., O'Donohue, M.F., Montel-Lehry, N., Amor, D.J., McCarroll, S.A., O'Donnell-Luria, A.H., Gupta, N., Gabriel, S.B., MacArthur, D.G., Lander, E.S., Lek, M., Da Costa, L., Nathan, D.G., Korostelev, A.A., Do, R., Sankaran, V.G. and Gazda, H.T.
American Journal of Human Genetics 103
(6): 930-947.
6 December 2018
Refined staging by sentinel lymph node biopsy to individualize therapy in anal cancer.
Ulmer, C., Bembenek, A., Gretschel, S., Markwardt, J., Koswig, S., Schneider, U. and Schlag, P.M.
Annals of Surgical Oncology 11
(Supplement 3): 259S-262S.
March 2004
Sentinel node biopsy in anal cancer - a promising strategy to individualize therapy.
Ulmer, C., Bembenek, A., Gretschel, S., Markwardt, J., Koswig, S., Slisow, W., Schneider, U. and Schlag, P.M.
Onkologie 26
(5): 456-460.
October 2003
Synovialsarkome der Extremitaeten - Ergebnisse chirurgischer und multimodaler Therapie [Synovial sarcoma of the extremities. Results of surgical and multimodal therapy].
Ulmer, C., Kettelhack, C., Tunn, P.U., Reichardt, P., Hohenberger, P. and Schlag, P.M.
Chirurg 74
(4): 370-374.
April 2003
covRNA: discovering covariate associations in large-scale gene expression data.
Urban, L., Remmele, C.W., Dittrich, M., Schwarz, R.F. and Müller, T.
BMC Research Notes 13
(1): 92.
24 February 2020
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta, E.C., Vieira-Vieira, C.H., Hick, T., Wessels, H.H., Figini, D., Moschall, R., Medenbach, J., Ohler, U., Granneman, S., Selbach, M. and Beckmann, B.M.
Nature Communications 10
(1): 990.
1 March 2019
Activation and nuclear translocation of mitogen-activated protein kinases by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase.
Urich, M., el Shemerly, M.Y., Besser, D., Nagamine, Y. and Ballmer-Hofer, K.
Journal of Biological Chemistry 270
(49): 29286-29292.
8 December 1995
RCAS: an RNA centric annotation system for transcriptome-wide regions of interest.
Uyar, B., Yusuf, D., Wurmus, R., Rajewsky, N., Ohler, U. and Akalin, A.
Nucleic Acids Research 45
(10): e91.
2 June 2017
Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.
Vaeth, M., Schliesser, U., Mueller, G., Reissig, S., Satoh, K., Tuettenberg, A., Jonuleit, H., Waisman, A., Mueller, M.R., Serfling, E., Sawitzki, B.S. and Berberich-Siebelt, F.
Proceedings of the National Academy of Sciences of the United States of America 109
(40): 16258-16263.
2 October 2012
Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.
Vaeth, M., Mueller, G., Stauss, D., Dietz, L., Klein-Hessling, S., Serfling, E., Lipp, M., Berberich, I. and Berberich-Siebelt, F.
Journal of Experimental Medicine 211
(3): 545-561.
10 March 2014
Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors.
Valenti, G., Quinn, H.M., Heynen, G.J.J.E., Lan, L., Holland, J.D., Vogel, R., Wulf-Goldenberg, A. and Birchmeier, W.
Cancer Research 77
(8): 2134-2147.
15 April 2017
A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P., Orgeur, M., Comai, G., Poehle-Kronnawitter, S., Fischer, C., Gloger, M., Dumas, C.E., Giesecke-Thiel, C., Sauer, S., Tajbakhsh, S., Höpken, U.E. and Stricker, S.
Immunity 56
(6): 1204-1219.
13 June 2023
Antitumor efficacy, pharmacokinetic and biodistribution studies of the anticancer peptide CIGB-552 in mouse models.
Vallespi, M.G., Pimentel, G., Cabrales-Rico, A., Garza, J., Oliva, B., Mendoza, O., Gomez, Y., Basaco, T., Sanchez, I., Calderon, C., Rodriguez, J.C., Markelova, M.R., Fichtner, I., Astrada, S., Bollati-Fogolín, M., Garay, H.E. and Reyes, O.
Journal of Peptide Science 20
(11): 850-859.
November 2014
Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain.
Van Steenwinckel, J., Schang, A.L., Krishnan, M.L., Degos, V., Delahaye-Duriez, A., Bokobza, C., Csaba, Z., Verdonk, F., Montané, A., Sigaut, S., Hennebert, O., Lebon, S., Schwendimann, L., Le Charpentier, T., Hassan-Abdi, R., Ball, G., Aljabar, P., Saxena, A., Holloway, R.K., Birchmeier, W., Baud, O., Rowitch, D., Miron, V., Chretien, F., Leconte, C., Besson, V.C., Petretto, E.G., Edwards, A.D., Hagberg, H., Soussi-Yanicostas, N., Fleiss, B. and Gressens, P.
Brain 142
(12): 3806-3833.
December 2019
Protein kinase B beta/Akt2 plays a specific role in muscle differentiation.
Vandromme, M., Rochat, A., Meier, R., Carnac, G., Besser, D., Hemmings, B.A., Fernandez, A. and Lamb, N.J.
Journal of Biological Chemistry 276
(11): 8173-8179.
16 March 2001
Clonally expanded PD-1-expressing T cells are enriched in synovial fluid of juvenile idiopathic arthritis patients.
Vanni, A., Mazzoni, A., Semeraro, R., Capone, M., Maschmeyer, P., Lamacchia, G., Salvati, L., Carnasciali, A., Farahvachi, P., Giani, T., Simonini, G., Filocamo, G., Romano, M., Liotta, F., Mashreghi, M.F., Cosmi, L., Cimaz, R., Magi, A., Maggi, L. and Annunziato, F.
European Journal of Immunology 53
(7): 2250162.
July 2023
The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.
Varano, G., Raffel, S., Sormani, M., Zanardi, F., Lonardi, S., Zasada, C., Perucho, L., Petrocelli, V., Haake, A., Lee, A.K., Bugatti, M., Paul, U., Van Anken, E., Pasqualucci, L., Rabadan, R., Siebert, R., Kempa, S., Ponzoni, M., Facchetti, F., Rajewsky, K. and Casola, S.
Nature 546
(7657): 302-306.
8 June 2017
Active MAC-1 (CD11b/CD18) on DC is inhibitory for full T cell activation.
Varga, G., Balkow, S., Wild, M.K., Stadtbaeumer, A., Krummen, M., Rothoeft, T., Higuchi, T., Beissert, S., Wethmar, K., Scharffetter-Kochanek, K., Vestweber, D. and Grabbe, S.
Blood 109
(2): 661-669.
15 January 2007
Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.
Varvaresou, A., Iakovou, K., Gikas, E., Fichtner, I., Fiebig, H.H., Kelland, L.R., Double, J.A., Bibby, M.C. and Hendriks, H.R.
Anticancer Research 24
(2): 907-919.
March 2004
Three-dimensional single molecule localization microscopy reveals the topography of the immunological synapse at isotropic precision below 15 nm.
Velas, L., Brameshuber, M., Huppa, J.B., Kurz, E., Dustin, M.L., Zelger, P., Jesacher, A. and Schütz, G.J.
Nano Letters 21
(21): 9247-9255.
10 November 2021
A multi-step transcriptional and chromatin state cascade underlies motor neuron programming from embryonic stem cells.
Velasco, S., Ibrahim, M.M., Kakumanu, A., Garipler, G., Aydin, B., Al-Sayegh, M.A., Hirsekorn, A., Abdul-Rahman, F., Satija, R., Ohler, U., Mahony, S. and Mazzoni, E.O.
Cell Stem Cell 20
(2): 205-217.
2 February 2017
Harnessing CD3 diversity to optimize CAR T cells.
Velasco Cárdenas, R.M.H., Brandl, S.M., Meléndez, A.V., Schlaak, A.E., Buschky, A., Peters, T., Beier, F., Serrels, B., Taromi, S., Raute, K., Hauri, S., Gstaiger, M., Lassmann, S., Huppa, J.B., Boerries, M., Andrieux, G., Bengsch, B., Schamel, W.W. and Minguet, S.
Nature Immunology 24
(12): 2135-2149.
December 2023
Human haematopoietic stem cell lineage commitment is a continuous process.
Velten, L., Haas, S.F., Raffel, S., Blaszkiewicz, S., Islam, S., Hennig, B.P., Hirche, C., Lutz, C., Buss, E.C., Nowak, D., Boch, T., Hofmann, W.K., Ho, A.D., Huber, W., Trumpp, A., Essers, M.A.G. and Steinmetz, L.M.
Nature Cell Biology 19
(4): 271-281.
April 2017
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Velten, L., Story, B.A., Hernández-Malmierca, P., Raffel, S., Leonce, D.R., Milbank, J., Paulsen, M., Demir, A., Szu-Tu, C., Frömel, R., Lutz, C., Nowak, D., Jann, J.C., Pabst, C., Boch, T., Hofmann, W.K., Müller-Tidow, C., Trumpp, A., Haas, S. and Steinmetz, L.M.
Nature Communications 12
(1): 1366.
1 March 2021
Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses.
Ventura, P.M.O., Gakovic, M., Fischer, B.A., Spinelli, L., Rota, G., Pathak, S., Khameneh, H.J., Zenobi, A., Thomson, S., Birchmeier, W., Cantrell, D.A. and Guarda, G.
EMBO Reports 23
(11): e55399.
7 November 2022
Daratumumab as a novel treatment option in refractory ITP.
Vernava, I. and Schmitt, C.A.
Blood Cells Molecules and Diseases 99
: 102724.
March 2023
HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice.
Vertuani, S., Triulzi, C., Roos, A.K., Charo, J., Norell, H., Lemonnier, F., Pisa, P., Seliger, B. and Kiessling, R.
Cancer Immunology Immunotherapy 58
(5): 653-664.
May 2009
An experimental setup for frequency domain FLIM.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
FLIM measurements and frequency domain FLIM data analysis.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
Imaging protein interactions by FRET microscopy: FLIM measurements.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
Imaging protein interactions by FRET microscopy: FRET measurements by acceptor photobleaching.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
Imaging protein interactions by FRET microscopy: FRET measurements by sensitized emission.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
Imaging protein interactions by FRET microscopy: cell preparation for FRET analysis.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
Imaging protein interactions by FRET microscopy: labeling proteins with fluorescent dyes.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
Measuring FRET by acceptor photobleaching.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
Measuring FRET by sensitized emission.
Verveer, P.J., Rocks, O., Harpur, A.G. and Bastiaens, P.I.H.
Cold Spring Harbor Protocols 2006
(6)
1 November 2006
A barcoded flow cytometric assay to explore the antibody responses against SARS-CoV-2 spike and its variants.
Vesper, N., Ortiz, Y., Bartels-Burgahn, F., Yang, J., de la Rosa, K., Tenbusch, M., Schulz, S., Finzel, S., Jäck, H.M., Eibel, H., Voll, R.E. and Reth, M.
Frontiers in Immunology 12
: 730766.
September 2021
Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment.
Vidal, V.P., Chaboissier, M.C., Luetzkendorf, S., Cotsarelis, G., Mill, P., Hui, C.C., Ortonne, N., Ortonne, J.P. and Schedl, A.
Current Biology 15
(15): 1340-1351.
9 August 2005
Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H., Dauksaite, V., Sporbert, A., Gotthardt, M. and Selbach, M.
Molecular Cell 82
(11): 2069-2083.
2 June 2022
Expression of mGluR5 in pediatric Hodgkin and Non-Hodgkin lymphoma-a comparative analysis of immunohistochemical and clinical findings regarding the association between tumor and paraneoplastic neurological disease.
Viezens, I., Knierim, E., Deubzer, H.E., Hauptmann, K., Fassbender, J., Morales-Gonzalez, S., Kaindl, A.M., Schuelke, M. and Nikolaus, M.
Cancers 16
(13): 2452.
4 July 2024
Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury.
Vigolo, E., Markó, L., Hinze, C., Müller, D.N., Schmidt-Ullrich, R. and Schmidt-Ott, K.M.
Kidney International 95
(1): 108-122.
January 2019
Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis.
Visekruna, A., Joeris, T., Seidel, D., Kroesen, A., Loddenkemper, C., Zeitz, M., Kaufmann, S.H.E., Schmidt-Ullrich, R. and Steinhoff, U.
Journal of Clinical Investigation 116
(12): 3195-3203.
December 2006
The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells.
Viñado, A.C., Calvo, I.A., Cenzano, I., Olaverri, D., Cocera, M., San Martin-Uriz, P., Romero, J.P., Vilas-Zornoza, A., Vera, L., Gomez-Cebrian, N., Puchades-Carrasco, L., Lisi-Vega, L.E., Apaolaza, I., Valera, P., Guruceaga, E., Granero-Molto, F., Ripalda-Cemborain, P., Luck, T.J., Bullinger, L., Planes, F.J., Rifon, J.J., Méndez-Ferrer, S., Yusuf, R.Z., Pardo-Saganta, A., Prosper, F. and Saez, B.
Leukemia 36
(8): 1969-1979.
August 2022
Short tandem repeats in the inhibitory domain of the mineralocorticoid receptor: prediction of a β-solenoid structure.
Vlassi, M., Brauns, K. and Andrade-Navarro, M.A.
BMC Structural Biology 13
(1): 17.
2 October 2013
Cluster-independent marker feature identification from single-cell omics data using SEMITONES.
Vlot, A.H.C., Maghsudi, S. and Ohler, U.
Nucleic Acids Research 50
(18): e107.
14 October 2022
Dynamic subcompartmentalization of the mitochondrial inner membrane.
Vogel, F., Bornhoevd, C., Neupert, W. and Reichert, A.S.
Journal of Cell Biology 175
(2): 237-247.
23 October 2006
NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes.
Volcic, M., Karl, S., Baumann, B., Salles, D., Daniel, P., Fulda, S. and Wiesmueller, L.
Nucleic Acids Research 40
(1): 181-195.
January 2012
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Volk, T., Pannicke, U., Reisli, I., Bulashevska, A., Ritter, J., Björkman, A., Schäffer, A.A., Fliegauf, M., Sayar, E.H., Salzer, U., Fisch, P., Pfeifer, D., Di Virgilio, M., Cao, H., Yang, F., Zimmermann, K., Keles, S., Caliskaner, Z., Güner, S.Ü., Schindler, D., Hammarström, L., Rizzi, M., Hummel, M., Pan-Hammarstroem, Q., Schwarz, K. and Grimbacher, B.
Human Molecular Genetics 24
(25): 7361-7372.
20 December 2015
Increased mutation and gene conversion within human segmental duplications.
Vollger, M.R., Dishuck, P.C., Harvey, W.T., DeWitt, W.S., Guitart, X., Goldberg, M.E., Rozanski, A.N., Lucas, J., Asri, M., Munson, K.M., Lewis, A.P., Hoekzema, K., Logsdon, G.A., Porubsky, D., Paten, B., Harris, K., Hsieh, P.H. and Eichler, E.E.
Nature 617
(7960): 325-334.
11 May 2023
Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads.
Vollger, M.R., Logsdon, G.A., Audano, P.A., Sulovari, A., Porubsky, D., Peluso, P., Wenger, A.M., Concepcion, G.T., Kronenberg, Z.N., Munson, K.M., Baker, C., Sanders, A.D., Spierings, D.C.J., Lansdorp, P.M., Surti, U., Hunkapiller, M.W. and Eichler, E.E.
Annals of Human Genetics 84
(2): 125-140.
March 2020
Cannabidiol converts NF(κ)B into a tumor suppressor in glioblastoma with defined antioxidative properties.
Volmar, M.N.M., Cheng, J., Alenezi, H., Richter, S., Haug, A., Hassan, Z., Goldberg, M., Li, Y., Hou, M., Herold-Mende, C., Maire, C.L., Lamszus, K., Flüh, C., Held-Feindt, J., Gargiulo, G., Topping, G.J., Schilling, F., Saur, D., Schneider, G., Synowitz, M., Schick, J.A., Kälin, R.E. and Glass, R.
Neuro-Oncology 23
(11): 1898-1910.
November 2021
Early response to first-line anti-PD-1 treatment in Hodgkin lymphoma: a PET-based analysis from the prospective, randomized phase II NIVAHL trial.
Voltin, C.A., Mettler, J., van Heek, L., Goergen, H., Müller, H., Baues, C., Keller, U., Meissner, J., Trautmann-Grill, K., Kerkhoff, A., Fuchs, M., Sasse, S., von Tresckow, B., Dietlein, M., Borchmann, P., Engert, A., Kobe, C. and Bröckelmann, P.J.
Clinical Cancer Research 27
(2): 402-407.
January 2021
Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
Volz, T., Luetgehetmann, M., Allweiss, L., Warlich, M., Bierwolf, J., Pollok, J.M., Petersen, J., Matthes, E. and Dandri, M.
Antiviral Therapy 17
(4): 623-631.
27 February 2012
Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis.
Voorneveld, P.W., Stache, V., Jacobs, R.J., Smolders, E., Sitters, A.I., Liesker, A., Korkmaz, K.S., Lam, S.M., De Miranda, N.F.C.C., Morreau, H., Kodach, L.L. and Hardwick, J.C.H.
British Journal of Cancer 109
(7): 1805-1812.
1 October 2013
Hamster polyomavirus-derived virus-like particles are able to transfer in vitro encapsidated plasmid DNA to mammalian cells.
Voronkova, T., Kazaks, A., Ose, V., Oezel, M., Scherneck, S., Pumpens, P. and Ulrich, R.
Virus Genes 34
(3): 303-314.
June 2007
Acute promyelocytic leukemia: long-term outcomes from the HARMONY project.
Voso, M.T., Guarnera, L., Lehmann, S., Döhner, K., Döhner, H., Platzbecker, U., Russell, N.H., Dillon, R.J., Thomas, I., Ossenkoppele, G.J., Haferlach, T., Vignetti, M., La Sala, E., Piciocchi, A., Fazi, P., Villaverde Ramiro, Á., Tur Giménez, L., Gurnari, C., Bullinger, L. and Hernandez, J.M.
Blood
8 November 2024
(In Press)
Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K., Ullrich, F., Muench, J., Lazarow, K., Lutter, D., Mah, N., Andrade-Navarro, M.A., von Kries, J.P., Stauber, T. and Jentsch, T.J.
Science 344
(6184): 634-638.
9 May 2014
Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
Voutilainen, M., Lindfors, P.H., Lefebvre, S., Ahtiainen, L., Fliniaux, I., Rysti, E., Murtoniemi, M., Schneider, P., Schmidt-Ullrich, R. and Mikkola, M.L.
Proceedings of the National Academy of Sciences of the United States of America 109
(15): 5744-5749.
10 April 2012
Ectodysplasin/NF-κB promotes mammary cell fate via Wnt/β-catenin pathway.
Voutilainen, M., Lindfors, P.H., Trela, E., Loennblad, D., Shirokova, V., Elo, T., Rysti, E., Schmidt-Ullrich, R., Schneider, P. and Mikkola, M.L.
PLoS Genetics 11
(11): e1005676.
18 November 2015
Elevated MACC1 expression in colorectal cancer is driven by chromosomal instability and is associated with molecular subtype and worse patient survival.
Vuaroqueaux, V., Musch, A., Kobelt, D., Risch, T:, Herrmann, P., Burock, S., Peille, A.L., Yaspo, M.L., Fiebig, H.H. and Stein, U.
Cancers 14
(7): 1749.
1 April 2022
Reduced-intensity conditioning using fludarabine and antithymocyte globulin alone allows stable engraftment in a patient with Dyskeratosis congenita.
Vuong, L.G., Hemmati, P.G., Neuburger, S., Terwey, T.H., Vulliamy, T., Dokal, I., Le Coutre, P., Doerken, B. and Arnold, R.
Acta Haematologica 124
(4): 200-203.
December 2010
The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation.
Vučićević, D., Gehre, M., Dhamija, S., Friis-Hansen, L., Meierhofer, D., Sauer, S. and Ørom, U.A.
Oncotarget 7
(23): 33934-33947.
7 June 2016
Homo- and heteroassociations drive activation of ErbB3.
Váradi, T., Schneider, M., Sevcsik, E., Kiesenhofer, D., Baumgart, F., Batta, G., Kovács, T., Platzer, R., Huppa, J.B., Szöllősi, J., Schütz, G.J., Brameshuber, M. and Nagy, P.
Biophysical Journal 117
(10): 1935-1947.
19 November 2019
Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth.
Waaler, J., Machon, O., von Kries, J.P., Wilson, S.R., Lundenes, E., Wedlich, D., Gradl, D., Paulsen, J.E., Machonova, O., Dembinski, J.L., Dinh, H. and Krauss, S.
Cancer Research 71
(1): 197-205.
1 January 2011
Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood.
Wada, M., Bartram, C.R., Nakamura, H., Hachiya, M., Chen, D.L., Borenstein, J., Miller, C.W., Ludwig, L., Hansen-Hagge, T.E., Ludwig, W.D., Reiter, A., Mizoguchi, H. and Hoeffler, H.P.
Blood 82
(10): 3163-3169.
15 November 1993
Multiple molecular recognition mechanisms. Cytochrome P450 - A case study.
Wade, R.C., Motiejunas, D., Schleinkofer, K., Sudarko, Winn, P.J., Banerjee, A., Kariakin, A. and Jung, C.
Biochimica et Biophysica Acta - Proteins and Proteomics 1754
(1-2): 239-244.
16 September 2005
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload.
Waehre, A., Halvorsen, B., Yndestad, A., Husberg, C., Sjaastad, I., Nygard, S., Dahl, C.P., Ahmed, M.S., Finsen, A.V., Reims, H., Louch, W.E., Hilfiker-Kleiner, D., Vinge, L.E., Roald, B., Attramadal, H., Lipp, M., Gullestad, L., Aukrust, P. and Christensen, G.
PLoS ONE 6
(4): e18668.
18 April 2011
Breakthrough infections in SARS-CoV-2-vaccinated multiple myeloma patients improve cross-protection against omicron variants.
Wagner, A., Garner-Spitzer, E., Auer, C., Gattinger, P., Zwazl, I., Platzer, R., Orola-Taus, M., Pichler, P., Amman, F., Bergthaler, A., Huppa, J.B., Stockinger, H., Zielinski, C.C., Valenta, R., Kundi, M. and Wiedermann, U.
Vaccines 12
(5): 518.
9 May 2024
Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
Wagner, K., Zhang, P., Rosenbauer, F., Drescher, B., Kobayashi, S., Radomska, H.S., Kutok, J.L., Gilliland, D.G., Krauter, J. and Tenen, D.G.
Proceedings of the National Academy of Sciences of the United States of America 103
(16): 6338-6343.
18 April 2006
Epigenetic and genetic analysis of the survivin promoter in acute myeloid leukemia.
Wagner, M., Schmelz, K., Doerken, B. and Tamm, I.
Leukemia Research 32
(7): 1054-1060.
July 2008
Transcriptional regulation of human survivin by early growth response (Egr)-1 transcription factor.
Wagner, M., Schmelz, K., Doerken, B. and Tamm, I.
International Journal of Cancer 122
(6): 1278-1287.
15 March 2008
In vivo expression of survivin and its splice variant survivin-2B: Impact on clinical outcome in acute myeloid leukemia.
Wagner, M., Schmelz, K., Wuchter, C., Ludwig, W.D., Doerken, B. and Tamm, I.
International Journal of Cancer 119
: 1291-1297.
15 September 2006
Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching.
Wagner, A.S., Politi, A.Z., Ast, A., Bravo-Rodriguez, K., Baum, K., Buntru, A., Strempel, N.U., Brusendorf, L., Hänig, C., Boeddrich, A., Plassmann, S., Klockmeier, K., Ramirez-Anguita, J.M., Sanchez-Garcia, E., Wolf, J. and Wanker, E.E.
Journal of Molecular Biology 430
(12): 1725-1744.
8 June 2018
Light-switched inhibitors of protein tyrosine phosphatase PTP1B based on phosphonocarbonyl phenylalanine as photoactive phosphotyrosine mimetic.
Wagner, S., Schütz, A. and Rademann, J.
Bioorganic and Medicinal Chemistry 23
(12): 2839-2847.
15 June 2015
Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript.
Wahlster, L., Verboon, J.M., Ludwig, L.S., Black, S.C., Luo, W., Garg, K., Voit, R.A., Collins, R.L., Garimella, K., Costello, M., Chao, K.R., Goodrich, J.K., DiTroia, S.P., O’Donnell-Luria, A., Talkowski, M.E., Michelson, A.D., Cantor, A.B. and Sankaran, V.G.
Journal of Experimental Medicine 218
(6): e20210444.
7 June 2021
Perfluorocarbon particle size influences magnetic resonance signal and immunological properties of dendritic cells.
Waiczies, H., Lepore, S., Janitzek, N., Hagen, U., Seifert, F., Ittermann, B., Purfürst, B., Pezzutto, A., Paul, F., Niendorf, T. and Waiczies, S.
PLoS ONE 6
(7): e21981.
19 July 2011
Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.
Wakabayashi, A., Ulirsch, J.C., Ludwig, L.S., Fiorini, C., Yasuda, M., Choudhuri, A., McDonel, P., Zon, L.I. and Sankaran, V.G.
Proceedings of the National Academy of Sciences of the United States of America 113
(16): 4434-4439.
19 April 2016
Interference with cell cycle progression by parasitic genetic elements: Sleeping Beauty joins the club.
Walisko, O. and Ivics, Z.
Cell Cycle 5
(12): 1275-1280.
June 2006
Sleeping Beauty transposase modulates cell-cycle progression through interaction with Miz-1.
Walisko, O., Izsvak, Z., Szabo, K., Kaufman, C.D., Herold, S. and Ivics, Z.
Proceedings of the National Academy of Sciences of the United States of America 103
(11): 4062-4067.
14 March 2006
Transcriptional activities of the Sleeping Beauty transposon and shielding its genetic cargo with insulators.
Walisko, O., Schorn, A., Rolfs, F., Devaraj, A., Miskey, C., Izsvak, Z. and Ivics, Z.
Molecular Therapy 16
(2): 359-369.
February 2008
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.
Walker, L.S.K., Gulbranson-Judge, A., Flynn, S., Brocker, T., Raykundalia, C., Goodall, M., Foerster, R., Lipp, M. and Lane, P.
Journal of Experimental Medicine 190
(8): 1115-1122.
18 October 1999
Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection clusters based on integrated genomic surveillance, outbreak analysis and contact tracing in an urban setting.
Walker, A., Houwaart, T., Finzer, P., Ehlkes, L., Tyshaieva, A., Damagnez, M., Strelow, D., Duplessis, A., Nicolai, J., Wienemann, T., Tamayo, T., Kohns Vasconcelos, M., Hülse, L., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Däumer, M.P., Thielen, A., Kolbe-Busch, S., Göbels, K., Zotz, R., Pfeffer, K., Timm, J. and Dilthey, A.T.
Clinical Infectious Diseases 74
(6): 1039-1046.
15 March 2022
Purifying selection against pathogenic mitochondrial DNA in human T cells.
Walker, M.A., Lareau, C.A., Ludwig, L.S., Karaa, A., Sankaran, V.G., Regev, A. and Mootha, V.K.
New England Journal of Medicine 383
(16): 1556-1563.
15 October 2020
MHCII-independent CD4(+) T cells protect injured CNS neurons via IL-4.
Walsh, J.T., Hendrix, S., Boato, F., Smirnov, I., Zheng, J., Lukens, J.R., Gadani, S., Hechler, D., Gölz, G., Rosenberger, K., Kammertöns, T., Vogt, J., Vogelaar, C., Siffrin, V., Radjavi, A., Fernandez-Castaneda, A., Gaultier, A., Gold, R., Kanneganti, T.D., Nitsch, R., Zipp, F. and Kipnis, J.
Journal of Clinical Investigation 125
(2): 699-714.
2 February 2015
Expression of coagulation factors and their receptors in tumor tissue and coagulation factor upregulation in peripheral blood of patients with cerebral carcinoma metastases.
Walter, J., Handel, L.L., Brodhun, M., van Rossum, D., Hanisch, U.K., Liebmann, L., Heppner, F., Goldbrunner, R., Koch, A. and Kuhn, S.A.
Journal of cancer research and clinical oncology 138
(1): 141-151.
January 2012
Heat-inducible in vivo gene therapy of colon carcinoma by human mdr1 promoter-regulated tumor necrosis factor-alpha expression.
Walther, W., Arlt, F., Fichtner, I., Aumann, J., Stein, U. and Schlag, P.M.
Molecular Cancer Therapeutics 6
(1): 236-243.
January 2007
The activity of titanocene T against xenografted Caki-1 tumors.
Walther, W., Fichtner, I., Deally, A., Hogan, M. and Tacke, M.
Letters in Drug Design & Discovery 10
(5): 375-381.
June 2013
In vitro and in vivo investigations into the carbene copper bromide anticancer drug candidate WBC4.
Walther, W., Fichtner, I., Hackenberg, F., Streciwilk, W. and Tacke, M.
Letters in Drug Design & Discovery 11
(7): 825-832.
August 2014
Nonviral jet-injection technology for intratumoral in vivo gene transfer of naked DNA.
Walther, W., Fichtner, I., Schlag, P.M. and Stein, U.S.
Methods in Molecular Biology 542
: 195-208.
2009
Chemosensitization by diverging modulation by short-term and long-term TNF-α action on ABCB1 expression and NF-κB signaling in colon cancer.
Walther, W., Kobelt, D., Bauer, L., Aumann, J. and Stein, U.
International Journal of Oncology 47
(6): 2276-2285.
December 2015
Uptake, biodistribution, and time course of naked plasmid DNA trafficking after intratumoral in vivo jet injection.
Walther, W., Minow, T., Martin, R., Fichtner, I., Schlag, P.M. and Stein, U.
Human Gene Therapy 17
(6): 611-624.
15 June 2006
Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors.
Walther, W., Petkov, S., Kuvardina, O.N., Aumann, J., Kobelt, D., Fichtner, I., Lemm, M., Piontek, J., Blasig, I.E., Stein, U. and Schlag, P.M.
Gene Therapy 19
(5): 494-503.
May 2012
A seven-year storage report of good manufacturing practice-grade naked plasmid DNA: stability, topology, and in vitro/in vivo functional analysis.
Walther, W., Schmeer, M., Kobelt, D., Baier, R., Harder, A., Walhorn, V., Anselmetti, D., Aumann, J., Fichtner, I. and Schleef, M.
Human Gene Therapy Clinical Development 24
(4): 147-153.
December 2013
Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer.
Walther, W., Siegel, R., Kobelt, D., Knoesel, T., Dietel, M., Bembenek, A., Aumann, J., Schleef, M., Baier, R., Stein, U. and Schlag, P.M.
Clinical Cancer Research 14
(22): 7545-7553.
15 November 2008
Nonviral jet-injection gene transfer for efficient in vivo cytosine deaminase suicide gene therapy of colon carcinoma.
Walther, W., Stein, U., Fichtner, I., Kobelt, D., Aumann, J., Arlt, F. and Schlag, P.M.
Molecular Therapy 12
(6): 1176-1184.
29 September 2005
Jet-injection of short hairpin RNA-encoding vectors into tumor cells.
Walther, W., Stein, U. and Lage, H.
Methods in Molecular Biology 629
: 123-139.
2010
Use of the nuclease inhibitor aurintricarboxylic acid (ATA) for improved non-viral intratumoral in vivo gene transfer by jet-injection.
Walther, W., Stein, U., Siegel, R., Fichtner, I. and Schlag, P.M.
Journal of Gene Medicine 7
(4): 477-485.
1 January 2005
Rapid method of total RNA mini-preparation from eucaryotic cells.
Walther, W., Stein, U. and Uckert, W.
Nucleic Acids Research 21
(7): 1682.
11 April 1993
Stability analysis for long-term storage of naked DNA: impact on nonviral in vivo gene transfer.
Walther, W., Stein, U., Voss, C., Schmidt, T., Schleef, M. and Schlag, P.M.
Analytical Biochemistry 318
(2): 230-235.
15 July 2003
TransTACs: novel heterobispecific antibodies for targeted protein degradation in cancer therapy.
Walther, W., Torke, S. and Stein, U.
Signal Transduction and Targeted Therapy 9
(1): 331.
26 November 2024
In-vitro and in-vivo investigations into the carbene-gold anticancer drug candidates NHC*-Au-SCSNMe(2) and NHC*-Au-S-GLUC against advanced prostate cancer PC3.
Walther, W., Althagafi, D., Curran, D., O'Beirne, C., Mc Carthy, C., Ott, I., Basu, U., Büttner, B., Sterner-Kock, A., Müller-Bunz, H., Sánchez-Sanz, G., Zhu, X. and Tacke, M.
Anti-Cancer Drugs 31
(7): 672-683.
August 2020
In vitro and in vivo investigations into the carbene gold chloride and thioglucoside anticancer drug candidates NHC-AuCl and NHC-AuSR.
Walther, W., Dada, O., O’Beirne, C., Ott, I., Sanchez-Sanz, G., Schmidt, C., Werner, C., Zhu, X. and Tacke, M.
Letters in Drug Design & Discovery 14
(2): 125-134.
2017
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.
Waltho, A., Popp, O., Lenz, C., Pluska, L., Lambert, M., Dötsch, V., Mertins, P. and Sommer, T.
Life Science Alliance 7
(8): e202402740.
August 2024
In-vivo tumor imaging using a novel RNAi-based detection mechanism.
Wan, K., Ebert, B., Voigt, J., Wang, Q., Dai, Y., Haag, R. and Kemmner, W.
Nanomedicine 8
(4): 393-398.
May 2012
In silico screening for pathogenesis related-2 gene candidates in Vigna uguiculata transcriptome.
Wanderley-Nogueira, A.C., Da Mota Soares-Cavalcanti, N., Belarmino, L.C., Barbosa-Silva, A., Kido, E.A., Do Monte, S.J.H., Pandolfi, V., Calsa-Junior, T. and Benko-Iseppon, A.M.
Lecture Notes in Computer Science 6160
: 70-81.
2010
Crystal structure of the yeast TRAPP-associated protein Tca17.
Wang, C., Gohlke, U., Roske, Y. and Heinemann, U.
FEBS Journal 281
(18): 4195-4206.
September 2014
[Effect of cell surface sialic acid and their linkages on adhesion of mammary carcinoma cells].
Wang, X.Y., Lin, S.Q., Li, J.W., Kemmner, W. and Ding, Y.Q.
Journal of Southern Medical University 26
: 742-746.
June 2006
Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
Wang, D., Höing, S., Patterson, H.C., Ahmad, U.M., Rathinam, V.A.K., Rajewsky, K., Fitzgerald, K.A. and Golenbock, D.T.
Journal of Biological Chemistry 288
(7): 4594-4601.
15 February 2013
Anti-angiogenesis and anti-immunosuppression gene therapy through targeting COUP-TFII in an in situ glioblastoma mouse model.
Wang, F., Zhang, S., Sun, F., Chen, W., Liu, C., Dong, H., Cui, B., Li, L., Sun, C., Du, W., Liu, B., Fan, W., Deng, J., Schmitt, C.A., Wang, X. and Du, J.
Cancer Gene Therapy 31
(8): 1135-1150.
August 2024
Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Wang, J., Brackmann, M., Castaño-Díez, D., Kudryashev, M., Goldie, K.N., Maier, T., Stahlberg, H. and Basler, M.
Nature Microbiology 2
(11): 1507-1512.
November 2017
Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J., Xie, G., Singh, M., Ghanbarian, A.T., Raskó, T., Szvetnik, A., Cai, H., Besser, D., Prigione, A., Fuchs, N.V., Schumann, G.G., Chen, W., Lorincz, M.C., Ivics, Z., Hurst, L.D. and Izsvák, Z.
Nature 516
(7531): 405-409.
18 December 2014
Wdr66 is a novel marker for risk stratification and involved in epithelial-mesenchymal transition of esophageal squamous cell carcinoma.
Wang, Q., Ma, C. and Kemmner, W.
BMC Cancer 13
(1): 137.
21 March 2013
De novo protein structure determination from near-atomic-resolution cryo-EM maps.
Wang, R.Y.R., Kudryashev, M., Li, X., Egelman, E.H., Basler, M., Cheng, Y., Baker, D. and DiMaio, F.
Nature Methods 12
(4): 335-338.
April 2015
Decitabine inhibits T cell proliferation via a novel TET2-dependent mechanism and exerts potent protective effect in mouse auto- and allo-immunity models.
Wang, X., Wang, J., Yu, Y., Ma, T., Chen, P., Zhou, B. and Tao, R.
Oncotarget 8
(34): 56802-56815.
22 August 2017
TLR7 signaling drives the development of Sjögren's syndrome.
Wang, Y., Roussel-Queval, A., Chasson, L., Hanna Kazazian, N., Marcadet, L., Nezos, A., Sieweke, M.H., Mavragani, C. and Alexopoulou, L.
Frontiers in Immunology 12
: 676010.
24 May 2021
EBI2 is highly expressed in multiple sclerosis lesions and promotes early CNS migration of encephalitogenic CD4 T cells.
Wanke, F., Moos, S., Croxford, A.L., Heinen, A.P., Gräf, S., Kalt, B., Tischner, D., Zhang, J., Christen, I., Bruttger, J., Yogev, N., Tang, Y., Zayoud, M., Israel, N., Karram, K., Reißig, S., Lacher, S.M., Reichhold, C., Mufazalov, I.A., Ben-Nun, A., Kuhlmann, T., Wettschureck, N., Sailer, A.W., Rajewsky, K., Casola, S., Waisman, A. and Kurschus, F.C.
Cell Reports 18
(5): 1270-1284.
31 January 2017
Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate.
Wardelmann, E., Merkelbach-Bruse, S., Pauls, K., Thomas, N., Schildhaus, H.U., Heinicke, T., Speidel, N., Pietsch, T., Buettner, R., Pink, D., Reichardt, P. and Hohenberger, P.
Clinical Cancer Research 12
: 1743-1749.
15 March 2006
Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors.
Wardelmann, E., Hrychyk, A., Merkelbach-Bruse, S., Pauls, K., Goldstein, J., Hohenberger, P., Losen, I., Manegold, C., Buettner, R. and Pietsch, T.
Journal of Molecular Diagnostics 6
: 197-204.
1 January 2003
Swarm Learning for decentralized and confidential clinical machine learning.
Warnat-Herresthal, S., Schultze, H., Shastry, K.L., Manamohan, S., Mukherjee, S., Garg, V., Sarveswara, R., Händler, K., Pickkers, P., Aziz, N.A., Ktena, S., Tran, F., Bitzer, M., Ossowski, S., Casadei, N., Herr, C., Petersheim, D., Behrends, U., Kern, F., Fehlmann, T., Schommers, P., Lehmann, C., Augustin, M., Rybniker, J., Altmüller, J., Mishra, N., Bernardes, J.P., Krämer, B., Bonaguro, L., Schulte-Schrepping, J., De Domenico, E., Siever, C., Kraut, M., Desai, M., Monnet, B., Saridaki, M., Siegel, C.M., Drews, A., Nuesch-Germano, M., Theis, H., Heyckendorf, J., Schreiber, S., Kim-Hellmuth, S., Nattermann, J., Skowasch, D., Kurth, I., Keller, A., Bals, R., Nürnberg, P., Rieß, O., Rosenstiel, P., Netea, M.G., Theis, F., Mukherjee, S., Backes, M., Aschenbrenner, A.C., Ulas, T., Breteler, M.M.B., Giamarellos-Bourboulis, E.J., Kox, M., Becker, M., Cheran, S., Woodacre, M.S., Goh, E.L. and Schultze, J.L.
Nature 594
(7862): 265-270.
10 June 2021
Synthesis and biological activity of water-soluble maleimide derivatives of the anticancer drug Carboplatin designed as albumin-binding prodrugs.
Warnecke, A., Fichtner, I., Garmann, D., Jaehde, U. and Kratz, F.
Bioconjugate Chemistry 15
(6): 1349-1359.
1 November 2004
Synthesis, cleavage profile, and antitumor efficacy of an albumin-binding prodrug of methotrexate that is cleaved by plasmin and cathepsin B.
Warnecke, A., Fichtner, I., Sass, G. and Kratz, F.
Archiv der Pharmazie 340
(8): 389-395.
August 2007
Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility.
Warren, W.C., Harris, R.A., Haukness, M., Fiddes, I.T., Murali, S.C., Fernandes, J., Dishuck, P.C., Storer, J.M, Raveendran, M., Hillier, L.W., Porubsky, D., Mao, Y., Gordon, D., Vollger, M.R., Lewis, A.P., Munson, K.M., DeVogelaere, E., Armstrong, J., Diekhans, M., Walker, J.A., Tomlinson, C., Graves-Lindsay, T.A., Kremitzki, M., Salama, S.R., Audano, P.A., Escalona, M., Maurer, N.W., Antonacci, F., Mercuri, L., Maggiolini, F.A.M., Catacchio, C.R., Underwood, J.G., O'Connor, D.H., Sanders, A.D., Korbel, J.O., Ferguson, B., Kubisch, H.M., Picker, L., Kalin, N.H., Rosene, D., Levine, J., Abbott, D.H., Gray, S.B., Sanchez, M.M., Kovacs-Balint, Z.A., Kemnitz, J.W., Thomasy, S.M., Roberts, J.A., Kinnally, E.L., Capitanio, J.P., Skene, J.H.Pate, Platt, M., Cole, S.A., Green, R.E., Ventura, M., Wiseman, R.W., Paten, B., Batzer, M.A., Rogers, J. and Eichler, E.E.
Science 370
(6523): eabc6617.
18 December 2020
Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability.
Waseem, A., Karsten, U., Leigh, I.M., Purkis, P., Waseem, N.H. and Lane, E.B.
Biochemistry 43
(5): 1283-1295.
1 January 2004
In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms.
Wassermann, B., Kummrow, A., Moesta, K.T., Grosenick, D., Mucke, J., Wabnitz, H., Moeller, M., Macdonald, R., Schlag, P.M. and Rinneberg, H.
Optics Express 13
: 8571-8583.
1 January 2005
Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.
Watkins, T.B.K., Colliver, E.C., Huska, M.R., Kaufmann, T.L., Lim, E.L., Duncan, C.B., Haase, K., Van Loo, P., Swanton, C., McGranahan, N. and Schwarz, R.F.
PLoS Computational Biology 19
(10): e1011379.
23 October 2023
Pervasive chromosomal instability and karyotype order in tumour evolution.
Watkins, T.B.K., Lim, E.L., Petkovic, M., Elizalde, S., Birkbak, N.J., Wilson, G.A., Moore, D.A., Grönroos, E., Rowan, A., Dewhurst, S.M., Demeulemeester, J., Dentro, S.C., Horswell, S., Au, L., Haase, K., Escudero, M., Rosenthal, R., Bakir, M.A., Xu, H., Litchfield, K., Lu, W.T., Mourikis, T.P., Dietzen, M., Spain, L., Cresswell, G.D., Biswas, D., Lamy, P., Nordentoft, I., Harbst, K., Castro-Giner, F., Yates, L.R., Caramia, F., Jaulin, F., Vicier, C., Tomlinson, I.P.M., Brastianos, P.K., Cho, R.J., Bastian, B.C., Dyrskjøt, L., Jönsson, G.B., Savas, P., Loi, S., Campbell, P.J., Andre, F., Luscombe, N.M., Steeghs, N., Tjan-Heijnen, V.C.G., Szallasi, Z., Turajlic, S., Jamal-Hanjani, M., Van Loo, P., Bakhoum, S.F., Schwarz, R.F., McGranahan, N. and Swanton, C.
Nature 587
(7832): 126-132.
5 November 2020
Phylogenetic quantification of intratumor heterogeneity.
Watkins, T.B.K. and Schwarz, R.F.
Cold Spring Harbor Perspectives in Medicine 8
(4): a028316.
April 2018
Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A., Cohen, I., Popp, O., Dittmar, G., Reiss, Y., Sommer, T., Ravid, T. and Jarosch, E.
Molecular Cell 63
(5): 827-839.
1 September 2016
PEDL+: Protein-centered relation extraction from PubMed at your fingertip.
Weber, L., Barth, F., Lorenz, L., Konrath, F., Huska, K., Wolf, J. and Leser, U.
Bioinformatics 39
(11): btad603.
November 2023
Chemical-protein relation extraction with ensembles of carefully tuned pretrained language models.
Weber, L., Sänger, M., Garda, S., Barth, F., Alt, C. and Leser, U.
Database 2022
: baac098.
18 November 2022
HunFlair: an easy-to-use tool for state-of-the-art biomedical named entity recognition.
Weber, L., Sänger, M., Münchmeyer, J., Habibi, M., Leser, U. and Akbik, A.
Bioinformatics 37
(17): 2792–2794.
1 September 2021
PEDL: extracting protein-protein associations using deep language models and distant supervision.
Weber, L., Thobe, K., Migueles Lozano, O.A., Wolf, J. and Leser, U.
Bioinformatics 36
(Suppl 1): i490-i498.
July 2020
4EHP and GIGYF1/2 mediate translation-coupled messenger RNA decay.
Weber, R., Chung, M.Y., Keskeny, C., Zinnall, U., Landthaler, M., Valkov, E., Izaurralde, E. and Igreja, C.
Cell Reports 33
(2): 108262.
13 October 2020
Caspase-mediated apoptosis induction in zebrafish cerebellar Purkinje neurons.
Weber, T., Namikawa, K., Winter, B., Müller-Brown, K., Kühn, R., Wurst, W. and Köster, R.W.
Development 143
(22): 4279-4287.
15 November 2016
Gene editing in mouse zygotes using the CRISPR/Cas9 system.
Wefers, B., Bashir, S., Rossius, J. and Kühn, R.
Methods 121-122
: 55-67.
15 May 2017
Genome editing in mice using TALE nucleases.
Wefers, B., Brandl, C., Ortiz, O., Wurst, W. and Kühn, R.
Methods in Molecular Biology 1338
: 229-243.
2016
Generation of targeted mouse mutants by embryo microinjection of TALENs.
Wefers, B., Ortiz, O., Wurst, W. and Kühn, R.
Methods 69
(1): 94-101.
15 August 2014
Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA.
Wefers, B., Panda, S.K., Ortiz, O., Brandl, C., Hensler, S., Hansen, J., Wurst, W. and Kühn, R.
Nature Protocols 8
(12): 2355-2379.
December 2013
Gene editing in mouse zygotes using the CRISPR/Cas9 system.
Wefers, B., Wurst, W. and Kühn, R.
Methods in Molecular Biology 2631
: 207-230.
2023
Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.
Wegener, E., Oeckinghaus, A., Papadopoulou, N., Lavitas, L., Schmidt-Supprian, M., Ferch, U., Mak, T.W., Ruland, J., Heissmeyer, V. and Krappmann, D.
Molecular Cell 23
(1): 13-23.
7 July 2006
HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells.
Wegener, D., Deubzer, H.E., Oehme, I., Milde, T., Hildmann, C., Schwienhorst, A. and Witt, O.
Anti-Cancer Drugs 19
(9): 849-857.
October 2008
Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay.
Wegener, D., Hildmann, C., Riester, D., Schober, A., Meyer-Almes, F.J., Deubzer, H.E., Oehme, I., Witt, O., Lang, S., Jaensch, M., Makarov, V., Lange, C., Busse, B. and Schwienhorst, A.
Biochemical Journal 413
(1): 143-150.
1 July 2008
Spatially restricted stromal Wnt signaling restrains prostate epithelial progenitor growth through direct and indirect mechanisms.
Wei, X., Zhang, L., Zhou, Z., Kwon, O.J., Zhang, Y., Nguyen, H., Dumpit, R., True, L., Nelson, P., Dong, B., Xue, W., Birchmeier, W., Taketo, M.M., Xu, F., Creighton, C.J., Ittmann, M.M. and Xin, L.
Cell Stem Cell 24
(5): 753-768.
2 May 2019
Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13).
Weichenhan, D., Riedel, A., Sollier, E., Toprak, U.H., Hey, J., Breuer, K.H., Wierzbinska, J.A., Touzart, A., Lutsik, P., Bähr, M., Östlund, A., Nilsson, T., Jacobsson, S., Waraky, A., Behrens, Y.L., Göhring, G., Schlegelberger, B., Steinek, C., Harz, H., Leonhardt, H., Dolnik, A., Reinhardt, D., Bullinger, L., Palmqvist, L., Lipka, D.B. and Plass, C.
Blood Advances 8
(19): 5100-5111.
8 October 2024
High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis.
Weichert, W., Boehm, M., Gekeler, V., Bahra, M., Langrehr, J., Neuhaus, P., Denkert, C., Imre, G., Weller, C., Hofmann, H.P., Niesporek, S., Jacob, J., Dietel, M., Scheidereit, C. and Kristiansen, G.
British Journal of Cancer 97
: 523-530.
14 August 2007
Inducible expression of coding and inhibitory RNAs from retargetable genomic loci.
Weidenfeld, I., Gossen, M., Loew, R., Kentner, D., Berger, S., Goerlich, D., Bartsch, D., Bujard, H. and Schoenig, K.
Nucleic Acids Research 37
(7): e50.
April 2009
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Weidner, K.M., Dicesare, S., Sachs, M., Brinkmann, V., Behrens, J. and Birchmeier, W.
Nature 384
(6605): 173-176.
14 November 1996
The Met receptor tyrosine kinase transduces motility, proliferation, andmorphogenic signals of scatter factor/ hepatocyte growth factor in epithelial cells.
Weidner, K.M., Sachs, M. and Birchmeier, W.
Journal of Cell Biology 121
(1): 145-154.
April 1993
Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Weigert, R., Hetzel, S., Bailly, N., Haggerty, C., Ilik, I.A., Yung, P.Y.K., Navarro, C., Bolondi, A., Kumar, A.S., Anania, C., Brändl, B., Meierhofer, D., Lupianez, D.G., Müller, F.J., Aktas, T., Elsässer, S.J., Kretzmer, H., Smith, Z.D. and Meissner, A.
Nature Cell Biology 25
: 579–591.
April 2023
Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex.
Weigt, M., Gao, Q., Ban, H., He, H., Mastrobuoni, G., Kempa, S., Chen, W. and Li, F.
Epigenetics & Chromatin 14
(1): 8.
19 January 2021
Sequential mTOR inhibitor treatment with temsirolimus in metastatic renal cell carcinoma following failure of VEGF receptor tyrosine kinase inhibitors.
Weikert, S., Kempkensteffen, C., Busch, J., Johannsen, M., Gruenwald, V., Zimmermann, K., Floercken, A., Westermann, J., Weinkauf, L., Miller, K. and Keilholz, U.
World Journal of Urology 31
(4): 805-809.
August 2013
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A., Grau, M., Erdmann, T., Merkel, O., Sobhiafshar, U., Anagnostopoulos, I., Hummel, M., Siegert, A., Hayford, C., Madle, H., Wollert-Wulf, B., Fichtner, I., Dörken, B., Dirnhofer, S., Mathas, S., Janz, M., Emre, N.C.T., Rosenwald, A., Ott, G., Lenz, P., Tzankov, A. and Lenz, G.
Blood 125
(1): 124-132.
1 January 2015
Dual T cell receptor expressing CD8+ T cells with tumor- and self-specificity can inhibit tumor growth without causing severe autoimmunity.
Weinhold, M., Sommermeyer, D., Uckert, W. and Blankenstein, T.
Journal of Immunology 179
(8): 5534-5542.
15 October 2007
Epstein-Barr virus-associated B-cell lymphoma secondary to FCD-C therapy in patients with peripheral T-cell lymphoma.
Weisel, K.C., Weidmann, E., Anagnostopoulos, I., Kanz, L., Pezzutto, A. and Subklewe, M.
International Journal of Hematology 88
(4): 434-440.
November 2008
Ectopic expression of transcription factor BATF3 induces B-cell lymphomas in a murine B-cell transplantation model.
Weiser, C., Petkova, M.V., Rengstl, B., Döring, C., von Laer, D., Hartmann, S., Küppers, R., Hansmann, M.L. and Newrzela, S.
Oncotarget 9
(22): 15942-15951.
23 March 2018
Structural insights into the activation mechanism of antimicrobial GBP1.
Weismehl, M., Chu, X., Kutsch, M., Lauterjung, P., Herrmann, C., Kudryashev, M. and Daumke, O.
EMBO Journal 43
(4): 615-636.
15 February 2024
p21WAF1/CIP1 mutants deficient in inhibiting cyclin-dependent kinases (CDKs) can promote assembly of active cyclin D/CDK4(6) complexes in human tumor cells1.
Welcker, M., Lukas, J., Strauss, M. and Bartek, J.
Cancer Research 58
(22): 5053-5056.
15 November 1998
Role of the N-terminal region and of beta-sheet residue Thr29 on the activity of the omega(2) global regulator from the broad-host range Streptococcus pyogenes plasmid pSM19035.
Welfle, K., Pratto, F., Misselwitz, R., Behlke, J., Alonso, J.C. and Welfle, H.
Biological Chemistry 386
(9): 881-894.
1 September 2005
Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial.
Weller, J., Schäfer, N., Schaub, C., Tzaridis, T., Zeyen, T., Schneider, M., Potthoff, A.L., Giordano, F.A., Steinbach, J.P., Zeiner, P.S., Kowalski, T., Sabel, M., Hau, P., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Tabatabai, G., Ringel, F., Schmidt-Graf, F., Brehmer, S., Tonn, J.C., Bullinger, L., Vajkoczy, P., Glas, M., Vatter, H., Herrlinger, U. and Seidel, C.
Journal of Neuro-Oncology 161
(1): 147-153.
January 2023
Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.
Weller, J., Tzaridis, T., Mack, F., Steinbach, J.P., Schlegel, U., Hau, P., Krex, D., Grauer, O., Goldbrunner, R., Bähr, O., Uhl, M., Seidel, C., Tabatabai, G., Brehmer, S., Bullinger, L., Galldiks, N., Schaub, C., Kebir, S., Stummer, W., Simon, M., Fimmers, R., Coch, C., Glas, M., Herrlinger, U. and Schäfer, N.
Lancet Oncology 20
(10): 1444-1453.
October 2019
DAZL regulates Tet1 translation in murine embryonic stem cells.
Welling, M., Chen, H.H., Muñoz, J., Musheev, M.U., Kester, L., Junker, J.P., Mischerikow, N., Arbab, M., Kuijk, E., Silberstein, L., Kharchenko, P.V., Geens, M., Niehrs, C., van de Velde, H., van Oudenaarden, A., Heck, A.J. and Geijsen, N.
EMBO Reports 16
(7): 791-802.
July 2015
Combining Data Independent Acquisition with spike-in SILAC (DIA-SiS) improves proteome coverage and quantification.
Welter, A.S., Gerwien, M., Kerridge, R., Alp, K.M., Mertins, P. and Selbach, M.
Molecular & Cellular Proteomics 23
(10): 100839.
October 2024
Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma.
Welters, C., Lammoglia Cobo, M.F., Stein, C.A., Hsu, M.T., Ben Hamza, A., Penter, L., Chen, X., Buccitelli, C., Popp, O., Mertins, P., Dietze, K., Bullinger, L., Moosmann, A., Blanc, E., Beule, D., Gerbitz, A., Strobel, J., Hackstein, H., Rahn, H.P., Dornmair, K., Blankenstein, T. and Hansmann, L.
Cancer Immunology Research 10
(11): 1407-1419.
1 November 2022
HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation.
Welters, C., Welters, M.L., Stadler, S., Bullinger, L., Strobel, J., Hackstein, H., Dhamodaran, A., Blankenstein, T. and Hansmann, L.
Haematologica 109
(4): 1121-1127.
April 2024
Oligonucleotide library screening for identification of virus-specific T-cell receptors.
Welters, M.L., Stadler, S., Anastasopoulou, V., Bullinger, L., Leisegang, M., Kammertöns, T., Welters, C. and Hansmann, L.
European Journal of Immunology 56
(6): e2350908.
June 2024
Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.
Wend, P., Fang, L., Zhu, Q., Schipper, J.H., Loddenkemper, C., Kosel, F., Brinkmann, V., Eckert, K., Hindersin, S., Holland, J.D., Lehr, S., Kahn, M., Ziebold, U. and Birchmeier, W.
EMBO Journal 32
(14): 1977-1989.
17 July 2013
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.
Wendisch, D., Dietrich, O., Mari, T., von Stillfried, S., Ibarra, I.L., Mittermaier, M., Mache, C., Chua, R.L., Knoll, R., Timm, S., Brumhard, S., Krammer, T., Zauber, H., Hiller, A.L., Pascual-Reguant, A., Mothes, R., Bülow, R.D., Schulze, J., Leipold, A.M., Djudjaj, S., Erhard, F., Geffers, R., Pott, F., Kazmierski, J., Radke, J., Pergantis, P., Baßler, K., Conrad, C., Aschenbrenner, A.C., Sawitzki, B., Landthaler, M., Wyler, E., Horst, D., Hippenstiel, S., Hocke, A., Heppner, F.L., Uhrig, A., Garcia, C., Machleidt, F., Herold, S., Elezkurtaj, S., Thibeault, C., Witzenrath, M., Cochain, C., Suttorp, N., Drosten, C., Goffinet, C., Kurth, F., Schultze, J.L., Radbruch, H., Ochs, M., Eils, R., Müller-Redetzky, H., Hauser, A.E., Luecken, M.D., Theis, F.J., Conrad, C., Wolff, T., Boor, P., Selbach, M., Saliba, A.E. and Sander, L.E.
Cell 184
(26): 6243-6261.
22 December 2021
Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells.
Wendt, J., Radetzki, S., von Haefen, C., Hemmati, P.G., Guener, D., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 25
: 972-980.
16 February 2006
TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway.
Wendt, J., von Haefen, C., Hemmati, P., Belka, C., Doerken, B. and Daniel, P.T.
Oncogene 24
(25): 4052-4064.
1 January 2005
Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization.
Weng, Q., Wang, J., Wang, J., Wang, J., Sattar, F., Zhang, Z., Zheng, J., Xu, Z., Zhao, M., Liu, X., Yang, L., Hao, G., Fang, L., Lu, Q.R., Yang, B. and He, Q.
Cell Death & Disease 9
(2): 251.
14 February 2018
Functional mapping of human dynamin-1-like GTPase domain based on X-ray structure analyses.
Wenger, J., Klinglmayr, E., Fröhlich, C., Eibl, C., Gimeno, A., Hessenberger, M., Puehringer, S., Daumke, O. and Goettig, P.
PLoS ONE 8
(8): e71835.
19 August 2013
CXCR5- and CCR7-dependent lymphoid neogenesis in a murine model of chronic antigen-induced arthritis.
Wengner, A.M., Höpken, U.E., Petrow, P.K., Hartmann, S., Schurigt, U., Bräuer, R. and Lipp, M.
Arthritis and Rheumatism 56
(10): 3271-3283.
October 2007
Inhibition of metastasis in a murine 4T1 breast cancer model by liposomes preventing tumor cell-platelet interactions.
Wenzel, J., Zeisig, R. and Fichtner, I.
Clinical and Experimental Metastasis 27
(1): 25-34.
January 2010
Inhibition of breast cancer metastasis by dual liposomes to disturb complex formation.
Wenzel, J., Zeisig, R. and Fichtner, I.
International Journal of Pharmaceutics 370
(1-2): 121-128.
31 March 2009
Inhibition of pulmonary metastasis in a human MT3 breast cancer xenograft model by dual liposomes preventing intravasal fibrin clot formation.
Wenzel, J., Zeisig, R., Haider, W., Habedank, S. and Fichtner, I.
Breast Cancer Research and Treatment 121
(1): 13-22.
May 2010
Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway.
Wenzel, K., Daskalow, K., Herse, F., Seitz, S., Zacharias, U., Schenk, J.A., Schulz, H., Huebner, N., Micheel, B., Schlag, P.M., Osterziel, K.J., Ozcelik, C., Scherneck, S. and Jandrig, B.
Biological Chemistry 388
(5): 489-495.
May 2007
Identification and characterization of KAT, a novel gene preferentially expressed in several human cancer cell lines.
Wenzel, K., Felix, S.B., Flachmeier, C., Heere, P., Schulze, W., Grunewald, I., Pankow, H., Hewelt, A., Scherneck, S., Bauer, D. and Hoehe, M.R.
Biological Chemistry 384
(5): 763-775.
1 May 2003
MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.
Wenzel, S.S., Grau, M., Mavis, C., Hailfinger, S., Wolf, A., Madle, H., Deeb, G., Doerken, B., Thome, M., Lenz, P., Dirnhofer, S., Hernandez-Ilizaliturri, F.J., Tzankov, A. and Lenz, G.
Leukemia 27
(6): 1381-1390.
June 2013
High resolution crystal structure of domain I of the Saccharomyces cerevisiae homing endonuclease PI-SceI.
Werner, E., Wende, W., Pingoud, A. and Heinemann, U.
Nucleic Acids Research 30
(18): 3962-3971.
15 September 2002
Modes of TAL effector-mediated repression.
Werner, J. and Gossen, M.
Nucleic Acids Research 42
(21): 13061-13073.
1 December 2014
CXCR4-gerichtete Theranostics in der Hämato-Onkologie: Möglichkeiten und Herausforderungen [CXCR4-targeted theranostics in hematooncology: opportunities and challenges].
Werner, R., Haug, A., Buske, C., Heidegger, S., Illert, A.L., Bassermann, F., Herhaus, P., Buck, A., Duell, J., Topp, M.S., Kraus, S., Einsele, H., Lapa, C., Raderer, M., Lenz, G., Habringer, S., von Tresckow, B. and Keller, U.
Nuklearmedizin 63
(2): 57-61.
April 2024
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.
Werth, M., Walentin, K., Aue, A., Schoenheit, J., Wuebken, A., Pode-Shakked, N., Vilianovitch, L., Erdmann, B., Dekel, B., Bader, M., Barasch, J., Rosenbauer, F., Luft, F.C. and Schmidt-Ott, K.M.
Development 137
(22): 3835-3845.
November 2010
Myeloid transformation by MLL-ENL depends strictly on C/EBP.
Wesolowski, R., Kowenz-Leutz, E., Zimmermann, K., Dörr, D., Hofstätter, M., Slany, R.K., Mildner, A. and Leutz, A.
Life Science Alliance 4
(1): e202000709.
January 2021
Identifying RBP targets with RIP-seq.
Wessels, H.H., Hirsekorn, A., Ohler, U. and Mukherjee, N.
Methods in Molecular Biology 1358
: 141-152.
2016
The mRNA-bound proteome of the early fly embryo.
Wessels, H.H., Imami, K., Baltz, A.G., Kolinski, M., Beldovskaya, A., Selbach, M., Small, S., Ohler, U. and Landthaler, M.
Genome Research 26
(7): 1000-1009.
July 2016
Global identification of functional microRNA-mRNA interactions in Drosophila.
Wessels, H.H., Lebedeva, S., Hirsekorn, A., Wurmus, R., Akalin, A., Mukherjee, N. and Ohler, U.
Nature Communications 10
(1): 1626.
9 April 2019
Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study.
Westermann, J., Floercken, A., Willimsky, G., van Lessen, A., Kopp, J., Takvorian, A., Joehrens, K., Lukowsky, A., Schoenemann, C., Sawitzki, B., Pohla, H., Frank, R., Doerken, B., Schendel, D.J., Blankenstein, T. and Pezzutto, A.
Gene Therapy 18
(4): 354-363.
April 2011
Granulocyte macrophage-colony stimulating factor plus interleukin-2 plus alpha-interferon plus 5-fluorouracil in the treatment of metastatic renal cell cancer: induction of CD80/86+ T cells indicates adverse outcome.
Westermann, J., Hecker, A.C., Floercken, A., Doerken, B. and Pezzutto, A.
Journal of Immunotherapy 32
(6): 667-675.
July 2009
Cryopreservation of mature monocyte-derived human dendritic cells for vaccination: influence on phenotype and functional properties.
Westermann, J., Koerner, I.J., Kopp, J., Kurz, S., Zenke, M., Doerken, B. and Pezzutto, A.
Cancer Immunology Immunotherapy 52
(3): 194-198.
March 2003
Vaccination with autologous non-irradiated dendritic cells in patients with bcr/abl+ chronic myeloid leukaemia.
Westermann, J., Kopp, J., van Lessen, A., Hecker, A.C., Baskaynak, G., le Coutre, P., Doehner, K., Doehner, H., Doerken, B. and Pezzutto, A.
British Journal of Haematology 137
(4): 297-306.
May 2007
Simultaneous cytokine analysis by cytometric bead array for the detection of leukaemia-reactive T cells in patients with chronic myeloid leukaemia.
Westermann, J., Lessen, A., Schlimper, C., Baskaynak, G., Coutre, P., Doerken, B. and Pezzutto, A.
British Journal of Haematology 132
: 32-35.
January 2006
CD52 is not a promising immunotherapy target for most patients with multiple myeloma.
Westermann, J., Maschmeyer, G., Lessen, A., Doerken, B. and Pezzutto, A.
International Journal of Hematology 82
: 248-250.
1 October 2005
Flt-3 ligand as adjuvant for DNA vaccination augments immune responses but does not skew TH1/TH2 polarization.
Westermann, J., Nguyen-Hoai, T., Mollweide, A., Richter, G., Schmetzer, O., Kim, H.J., Blankenstein, T., Doerken, B. and Pezzutto, A.
Gene Therapy 11
(13): 1048-1056.
1 January 2004
T cell recognition of bcr/abl in healthy donors and in patients with chronic myeloid leukaemia.
Westermann, J., Schlimper, C., Richter, G., Mohm, J., Doerken, B. and Pezzutto, A.
British Journal of Haematology 125
(2): 213-216.
1 April 2004
CCL19 (ELC) as an adjuvant for DNA vaccination: induction of a TH1-type T-cell response and enhancement of antitumor immunity.
Westermann, J., Nguyen-Hoai, T., Baldenhofer, G., Höpken, U.E., Lipp, M., Dörken, B. and Pezzutto, A.
Cancer Gene Therapy 14
(6): 523-532.
June 2007
uORFdb - a comprehensive literature database on eukaryotic uORF biology.
Wethmar, K., Barbosa-Silva, A., Andrade-Navarro, M.A. and Leutz, A.
Nucleic Acids Research 42
(1): D60-D67.
1 January 2014
Migration of immature mouse DC across resting endothelium is mediated by ICAM-2 but independent of beta2-integrins and murine DC-SIGN homologues.
Wethmar, K., Helmus, Y., Luehn, K., Jones, C., Laskowska, A., Varga, G., Grabbe, S., Lyck, R., Engelhardt, B., Bixel, M.G., Butz, S., Loser, K., Beissert, S., Ipe, U., Vestweber, D. and Wild, M.K.
European Journal of Immunology 36
(10): 2781-2794.
October 2006
Comprehensive translational control of tyrosine kinase expression by upstream open reading frames.
Wethmar, K., Schulz, J., Muro, E.M., Talyan, S., Andrade-Navarro, M.A. and Leutz, A.
Oncogene 35
(13): 1736-1742.
31 March 2016
C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
Wethmar, K., Bégay, V., Smink, J.J., Zaragoza, K., Wiesenthal, V., Doerken, B., Calkhoven, C.F. and Leutz, A.
Genes & Development 24
(1): 15-20.
1 January 2010
Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.
Wetzel, C., Pifferi, S., Picci, C., Gök, C., Hoffmann, D., Bali, K.K., Lampe, A., Lapatsina, L., Fleischer, R., Smith, E.S.J., Bégay, V., Moroni, M., Estebanez, L., Kühnemund, J., Walcher, J., Specker, E., Neuenschwander, M., von Kries, J.P., Haucke, V., Kuner, R., Poulet, J.F.A., Schmoranzer, J., Poole, K. and Lewin, G.R.
Nature Neuroscience 20
(2): 209-218.
February 2017
Distinct genetic alterations and luminal molecular subtype in nested variant of urothelial carcinoma (NVUC).
Weyerer, V., Weisser, R., Moskalev, E.A., Haller, F., Stoehr, R., Eckstein, M., Zinnall, U., Gaisa, N.T., Compérat, E., Perren, A., Keck, B., Allory, Y., Kristiansen, G., Wullich, B., Agaimy, A., Hartmann, A. and Bertz, S.
Histopathology 75
(6): 865-875.
December 2019
Integrative functional genomics decodes herpes simplex virus 1.
Whisnant, A.W., Jürges, C.S., Hennig, T., Wyler, E., Prusty, B., Rutkowski, A.J., L'hernault, A., Djakovic, L., Göbel, M., Döring, K., Menegatti, J., Antrobus, R., Matheson, N.J., Künzig, F.W.H., Mastrobuoni, G., Bielow, C., Kempa, S., Liang, C., Dandekar, T., Zimmer, R., Landthaler, M., Grässer, F., Lehner, P.J., Friedel, C.C., Erhard, F. and Dölken, L.
Nature Communications 11
(1): 2038.
27 April 2020
The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer.
White, N.M.A., Youssef, Y.M., Fendler, A., Stephan, C., Jung, K. and Yousef, G.M.
Biological Chemistry 393
(5): 379-389.
May 2012
Transition from an autoimmune-prone state to fatal autoimmune disease in CCR7 and RORγt double-deficient mice is dependent on gut microbiota.
Wichner, K., Fischer, A., Winter, S., Tetzlaff, S., Heimesaat, M.M., Bereswill, S., Rehm, A., Lipp, M. and Höpken, U.E.
Journal of Autoimmunity 47
: 58-72.
December 2013
Dysregulated development of IL-17-and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORγt.
Wichner, K., Stauss, D., Kampfrath, B., Krüger, K., Müller, G., Rehm, A., Lipp, M. and Höpken, U.E.
FASEB Journal 30
(2): 761-774.
February 2016
Correlation of visinin-like-protein-1 expression with clinicopathological features in squamous cell carcinoma of the esophagus.
Wickborn, C., Klein-Szanto, A.J., Schlag, P.M. and Braunewell, K.H.
Molecular Carcinogenesis 45
: 572-581.
August 2006
TRANSAT-- method for detecting the conserved helices of functional RNA structures, including transient, pseudo-knotted and alternative structures.
Wiebe, N.J.P. and Meyer, I.M.
PLoS Computational Biology 6
(6): e1000823.
24 June 2010
Induction of ceramide-mediated apoptosis by the anticancer pPhospholipid analog, hexadecylphosphocholine.
Wieder, T., Orfanos, C.E. and Geilen, C.C.
Journal of Biological Chemistry 273
(18): 11025-11031.
1 May 1998
Analysis of translation initiation using a translation control reporter system.
Wiesenthal, V., Leutz, A. and Calkhoven, C.F.
Nature Protocols 1
(3): 1531-1537.
9 November 2006
A translation control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell.
Wiesenthal, V., Leutz, A. and Calkhoven, C.F.
Nucleic Acids Research 34
(3): e23.
10 February 2006
The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling.
Wijk, N.V., Witte, F., Feike, A.C., Schambony, A., Birchmeier, W., Mundlos, S. and Stricker, S.
Biochemical and Biophysical Research Communications 390
(2): 211-216.
11 December 2009
Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.
Wikman, H., Westphal, L., Schmid, F., Pollari, S., Kropidlowski, J., Sielaff-Frimpong, B., Glatzel, M., Matschke, J., Westphal, M., Iljin, K., Huhtala, H., Terracciano, L., Kallioniemi, A., Sauter, G., Mueller, V., Witzel, I., Lamszus, K., Kemming, D. and Pantel, K.
Oncotarget 5
(10): 3076-3087.
30 May 2014
Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity.
Wilde, S., Sommermeyer, D., Frankenberger, B., Schiemann, M., Milosevic, S., Spranger, S., Pohla, H., Uckert, W., Busch, D.H. and Schendel, D.J.
Blood 114
(10): 2131-2139.
3 September 2009
Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition.
Wilde, S., Sommermeyer, D., Leisegang, M., Frankenberger, B., Mosetter, B., Uckert, W. and Schendel, D.J.
Journal of Immunology 189
(2): 598-605.
15 July 2012
FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M.F., Lim, R., Zimmermann, B., Aspalter, I.M., Franco, C.A., Boettger, T., Braun, T., Fruttiger, M., Rajewsky, K., Keller, C., Brüning, J.C., Gerhardt, H., Carmeliet, P. and Potente, M.
Nature 529
(7585): 216-220.
14 January 2016
The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells.
Wilhelmi, Ilka, Grunwald, S., Gimber, N., Popp, O., Dittmar, G., Arumughan, A., Wanker, E.E., Laeger, T., Schmoranzer, J., Daumke, O. and Schümann, A.
Molecular Metabolism 45
: 101151.
March 2021
Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development.
Wilke, S., Groebe, L., Maffenbeier, V., Jaeger, V., Gossen, M., Josewski, J., Duda, A., Polle, L., Owens, R.J., Wirth, D., Heinz, D.W., van den Heuvel, J. and Buessow, K.
PLoS ONE 6
(12): e27829.
December 2011
Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting.
Wilke, S., Krausze, J., Gossen, M., Groebe, L., Jaeger, V., Gherardi, E., van den Heuvel, J. and Buessow, K.
Protein Science 19
(6): 1264-1271.
June 2010
SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C., Doebele, C., Zindel, A., Lee, K.S., Rieke, S.A., Ceribelli, M., Comoglio, F., Phelan, J.D., Wang, J.Q., Pikman, Y., Jahn, D., Häupl, B., Schneider, C., Scheich, S., Tosto, F.A., Bohnenberger, H., Stauder, P., Schnütgen, F., Slabicki, M., Coulibaly, Z.A., Wolf, S., Bojarczuk, K., Chapuy, B., Brandts, C.H., Stroebel, P., Lewis, C.A., Engelke, M., Xu, X., Kim, H., Dang, T.H., Schmitz, R., Hodson, D.J., Stegmaier, K., Urlaub, H., Serve, H., Schmitt, C.A., Kreuz, F., Knittel, G., Rabinowitz, J.D., Reinhardt, H.C., Vander Heiden, M.G., Thomas, C., Staudt, L.M., Zenz, T. and Oellerich, T.
Blood 139
(4): 538-553.
27 January 2022
Species- and tissue-specific expression of the C-terminal alternatively spliced form of the tumor suppressor p53.
Will, K., Warnecke, G., Bergman, S. and Deppert, W.
Nucleic Acids Research 23
(20): 4023-4028.
25 October 1995
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog).
Will, A.J., Cova, G., Osterwalder, M., Chan, W.L., Wittler, L., Brieske, N., Heinrich, V., de Villartay, J.P., Vingron, M., Klopocki, E., Visel, A., Lupiáñez, D.G. and Mundlos, S.
Nature Genetics 49
(10): 1539-1545.
October 2017
High salt inhibits tumor growth by enhancing anti-tumor immunity.
Willebrand, R., Hamad, I., Van Zeebroeck, L., Kiss, M., Bruderek, K., Geuzens, A., Swinnen, D., Côrte-Real, B.F., Markó, L., Lebegge, E., Laoui, D., Kemna, J., Kammertoens, T., Brandau, S., Van Ginderachter, J.A. and Kleinewietfeld, M.
Frontiers in Immunology 10
: 1141.
4 June 2019
The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney.
Willecke, R., Heuberger, J., Grossmann, K., Michos, O., Schmidt-Ott, K., Walentin, K., Costantini, F. and Birchmeier, W.
Developmental Biology 360
(2): 310-307.
15 December 2011
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.
Willer, A., Jakobsen, J.S., Ohlsson, E., Rapin, N., Waage, J., Billing, M., Bullinger, L., Karlsson, S. and Porse, B.T.
Leukemia 29
(5): 1018-1031.
May 2015
Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance.
Willimsky, G. and Blankenstein, T.
Nature 437
(7055): 141-146.
1 September 2005
Virus-induced hepatocellular carcinomas cause antigen-specific local tolerance.
Willimsky, G., Schmidt, K., Loddenkemper, C., Gellermann, J. and Blankenstein, T.
Journal of Clinical Investigation 123
(3): 1032-1043.
1 March 2013
In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo.
Willimsky, G., Beier, C., Immisch, L., Papafotiou, G., Scheuplein-Schlosser, V., Goede, A., Holzhütter, H.G., Blankenstein, T. and Kloetzel, P.M.
eLife 10
: e62019.
20 April 2021
Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness.
Willimsky, G., Czeh, M., Loddenkemper, C., Gellermann, J., Schmidt, K., Wust, P., Stein, H. and Blankenstein, T.
Journal of Experimental Medicine 205
(7): 1687-1700.
7 July 2008
Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Willnow, D., Benary, U., Margineanu, A., Vignola, M.L., Konrath, F., Pongrac, I.M., Karimaddini, Z., Vigilante, A., Wolf, J. and Spagnoli, F.M.
Nature 597
(7874): 87-91.
2 September 2021
Long-term observation of the frequency of secondary colorectal cancer and other malignancies in tyrosine kinase inhibitor treated chronic myeloid leukemia patients and controls.
Winkelmann, N., Schwarz, M., Hildebrandt, B., Henke, O., Bullinger, L., Na, I.K., Stintzing, S. and le Coutre, P.
eJHaem: The Official Journal of the British Society for Haematology 3
(3): 949-953.
August 2022
The cycling and aging mouse female reproductive tract at single-cell resolution.
Winkler, I., Tolkachov, A., Lammers, F., Lacour, P., Daugelaite, K., Schneider, N., Koch, M.L., Panten, J., Grünschläger, F., Poth, T., Ávila, B.M.d., Schneider, A., Haas, S., Odom, D.T. and Gonçalves, Â.
Cell 187
(4): 981-998.
15 February 2024
Mouse models of human multiple myeloma subgroups.
Winkler, W., Farré Díaz, C., Blanc, E., Napieczynska, H., Langner, P., Werner, M., Walter, B., Wollert-Wulf, B., Yasuda, T., Heuser, A., Beule, D., Mathas, S., Anagnostopoulos, I., Rosenwald, A., Rajewsky, K. and Janz, M.
Proceedings of the National Academy of Sciences of the United States of America 120
(10): e2219439120.
7 March 2023
Molecular mode of action and role of TP53 in the sensitivity to the novel epothilone sagopilone (ZK-EPO) in A549 non-small cell lung cancer cells.
Winsel, S., Sommer, A., Eschenbrenner, J., Mittelstaedt, K., Klar, U., Hammer, S. and Hoffmann, J.
PLoS ONE 6
(4): e19273.
29 April 2011
Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach.
Winter, A., Sigurdardottir, A.G., DiCara, D., Valenti, G., Blundell, T.L. and Gherardi, E.
Molecular Cancer Therapeutics 15
(1): 3-14.
January 2016
The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation.
Winter, S., Loddenkemper, C., Aebischer, A., Raebel, K., Hoffmann, K., Meyer, T.F., Lipp, M. and Höpken, U.E.
Journal of Molecular Medicine 88
(11): 1169-1180.
November 2010
Manifestation of spontaneous and early autoimmune gastritis in CCR7-deficient mice.
Winter, S., Rehm, A., Wichner, K., Scheel, T., Batra, A., Siegmund, B., Berek, C., Lipp, M. and Höpken, U.E.
American Journal of Pathology 179
(2): 754-765.
August 2011
EBAG9-silencing exerts an immune checkpoint function without aggravating adverse effects.
Wirges, A., Bunse, M., Joedicke, J.J., Blanc, E., Gudipati, V., Moles, M.W., Shiku, H., Beule, D., Huppa, J.B., Höpken, U.E. and Rehm, A.
Molecular Therapy 30
(11): 3358-3378.
2 November 2022
Mouse model for acute Epstein-Barr virus infection.
Wirtz, T., Weber, T., Kracker, S., Sommermann, T., Rajewsky, K. and Yasuda, T.
Proceedings of the National Academy of Sciences of the United States of America 113
(48): 13821-13826.
29 November 2016
Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use.
Wisskirchen, K., Metzger, K., Schreiber, S., Asen, T., Weigand, L., Dargel, C., Witter, K., Kieback, E., Sprinzl, M.F., Uckert, W., Schiemann, M., Busch, D.H., Krackhardt, A.M. and Protzer, U.
PLoS ONE 12
(8): e0182936.
8 August 2017
Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma or leukemia.
Witt, O., Milde, T., Deubzer, H.E., Oehme, I., Witt, R., Kulozik, A., Eisenmenger, A., Abel, U. and Karapanagiotou-Schenkel, I.
Klinische Padiatrie 224
(6): 398-403.
October 2012
Paired donor and recipient immunophenotyping in allogeneic hematopoietic stem cell transplantation: a cellular network approach.
Wittenbecher, F., Lesch, S., Kolling, S., Blau, I.W., Vuong, L., Borchert, F., Movasshagi, K., Tietze-Bürger, C., Penack, O., Ahn, J., Bullinger, L., Frentsch, M. and Na, I.K.
Frontiers in Immunology 13
: 874499.
23 May 2022
Rabbit antithymocyte globulin induces rapid expansion of effector memory CD8 T cells without accelerating acute graft versus host disease.
Wittenbecher, F., Rieger, K., Dziubianau, M., Herholz, A., Mensen, A., Blau, I.W., Uharek, L., Dörken, B., Thiel, A. and Na, I.K.
Leukemia Research Reports 2
(2): 82-85.
27 September 2013
Tumor suppressor activity of profilin requires a functional actin binding site.
Wittenmayer, N., Jandrig, B., Rothkegel, M., Schlueter, K., Arnold, W., Haensch, W., Scherneck, S. and Jockusch, B.M.
Molecular Biology of the Cell 15
(4): 1600-1608.
April 2004
The mTOR inhibitor temsirolimus added to rituximab combined with dexamethasone, cytarabine, and cisplatinum (R-DHAP) for the treatment of patients with relapsed or refractory DLBCL - results from the phase-II STORM trial.
Witzens-Harig, M., Viardot, A., Keller, U., Wosniok, J., Deuster, O., Klemmer, J., Geueke, A.M., Meißner, J., Ho, A.D., Atta, J., Marks, R., La Rosée, P., Buske, C., Dreyling, M.H. and Hess, G.
HemaSphere 5
(10): e636.
October 2021
Association of helicobacter pylori positivity with risk of disease and mortality.
Wizenty, J., Koop, P.H., Clusmann, J., Tacke, F., Trautwein, C., Schneider, K.M., Sigal, M. and Schneider, C.V.
Clinical and Translational Gastroenterology 14
(9): e00610.
September 2023
Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.
Wizenty, J., Müllerke, S., Kolesnichenko, M., Heuberger, J., Lin, M., Fischer, A.S., Mollenkopf, H.J., Berger, H., Tacke, F. and Sigal, M.
EMBO Journal 41
(13): e109996.
4 July 2022
Gastric stem cell biology and helicobacter pylori infection.
Wizenty, J. and Sigal, M.
Current Topics in Microbiology and Immunology 444
: 1-24.
18 January 2024
Retroperitoneal hematoma after bone marrow biopsy: the first cut should not be the deepest.
Wojciechowski, A., Duckert, M., Hartmann, J., Bullinger, L. and Matzdorff, A.
Oncology Research and Treatment 42
(5): 283-288.
May 2019
Downstream activation of a TATA-less promoter by Oct-2, Bob1, and NF-κB directs expression of the homing receptor BLR1 to mature B cells.
Wolf, I., Pevzner, V., Kaiser, E., Bernhardt, G., Claudio, E., Siebenlist, U., Foerster, R. and Lipp, M.
Journal of Biological Chemistry 273
(44): 28831-28836.
30 October 1998
Role of EBAG9 protein in coat protein complex I-dependent glycoprotein maturation and secretion processes in tumor cells.
Wolf, J., Reimer, T.A., Schuck, S., Rueder, C., Gerlach, K., Mueller, E.C., Otto, A., Doerken, B. and Rehm, A.
FASEB Journal 24
(10): 4000-4019.
October 2010
CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis.
Wolf, S.A., Steiner, B., Akpinarli, A., Kammertoens, T., Nassenstein, C., Braun, A., Blankenstein, T. and Kempermann, G.
Journal of Immunology 182
(7): 3979-3984.
1 April 2009
Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus.
Wolf, S.A., Steiner, B., Wengner, A.M., Lipp, M., Kammertoens, T. and Kempermann, G.
FASEB Journal 23
(9): 3121-3128.
September 2009
Dynamics of biochemical oscillators in a large number of interacting cells.
Wolf, J. and Heinrich, R.
Nonlinear Analysis Theory Methods & Applications 30
(3): 1835-1845.
December 1997
Coexpression of p21WAF1/CIP1 in adenovirus vector transfected human primary hepatocytes prevents apoptosis resulting in improved transgene expression.
Wolff, G., Schumacher, A., Nuessler, A.K., Ruppert, V., Karawajew, L., Wehnes, E., Neuhaus, P. and Doerken, B.
Gene Therapy 10
(8): 668-677.
April 2003
Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.
Wolfrum, C., Besser, D., Luca, E. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 100
(20): 11624-11629.
30 September 2003
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src.
Wong, B.R., Besser, D., Kim, N., Arron, J.R., Vologodskaia, M., Hanafusa, H. and Choi, Y.
Molecular Cell 4
(6): 1041-1049.
December 1999
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
Wong, J.B., Hewitt, S.L., Heltemes-Harris, L.M., Mandal, M., Johnson, K., Rajewsky, K., Koralov, S.B., Clark, M.R., Farrar, M.A. and Skok, J.A.
Nature Communications 10
(1): 4768.
18 October 2019
Interaction modulation through arrays of clustered methyl-arginine protein modifications.
Woodsmith, J., Casado-Medrano, V., Benlasfer, N., Eccles, R.L., Hutten, S., Heine, C.L., Thormann, V., Abou-Ajram, C., Rocks, O., Dormann, D. and Stelzl, U.
Life Science Alliance 1
(5): e201800178.
October 2018
The frequency of differentiated CD3(+)CD27(-)CD28(-) T cells predicts response to CART cell therapy in diffuse large B-cell lymphoma.
Worel, N., Grabmeier-Pfistershammer, K., Kratzer, B., Schlager, M., Tanzmann, A., Rottal, A., Körmöczi, U., Porpaczy, E., Staber, P.B., Skrabs, C., Herkner, H., Gudipati, V., Huppa, J.B., Salzer, B., Lehner, M., Saxenhuber, N., Friedberg, E., Wohlfarth, P., Hopfinger, G., Rabitsch, W., Simonitsch-Klupp, I., Jäger, U. and Pickl, W.F.
Frontiers in Immunology 13
: 1004703.
9 January 2022
Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract.
Worgall, S., Leopold, P.L., Wolff, G., Ferris, B., Van Roijen, N. and Crystal, R.G.
Human Gene Therapy 8
(14): 1675-1684.
20 September 1997
Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.
Worpenberg, L., Paolantoni, C., Longhi, S., Mulorz, M.M., Lence, T., Wessels, H.H., Dassi, E., Aiello, G., Sutandy, F.X.R., Scheibe, M., Edupuganti, R.R., Busch, A., Möckel, M.M., Vermeulen, M., Butter, F., König, J., Notarangelo, M., Ohler, U., Dieterich, C., Quattrone, A., Soldano, A. and Roignant, J.Y.
EMBO Journal 40
(4): e104975.
15 February 2021
Spatially resolved genome-wide transcriptional profiling identifies BMP signaling as essential regulator of zebrafish cardiomyocyte regeneration.
Wu, C.C., Kruse, F., Vasudevarao, M.D., Junker, J.P., Zebrowski, D.C., Fischer, K., Noel, E.S., Gruen, D., Berezikov, E., Engel, F.B., van Oudenaarden, A., Weidinger, G. and Bakkers, J.
Developmental Cell 36
(1): 36-49.
11 January 2016
Long-term suppression of tumor growth by TNF requires a Stat1- and IFN regulatory factor 1-dependent IFN-γ pathway but not IL-12 or IL-18.
Wu, T.H., Pabin, C.N., Qin, Z.H., Blankenstein, T., Philip, M., Dignam, J., Schreiber, K. and Schreiber, H.
Journal of Immunology 172
(5): 3243-3251.
1 January 2004
Bioprinted cancer model of neuroblastoma in a renal microenvironment as an efficiently applicable drug testing platform.
Wu, D., Berg, J., Arlt, B., Röhrs, V., Al-Zeer, M.A., Deubzer, H.E. and Kurreck, J.
International Journal of Molecular Sciences 23
(1): 122.
23 December 2021
Wnt signalling pathway in bladder cancer.
Wu, G., Weng, W., Xia, P., Yan, S., Zhong, C., Xie, L., Xie, Y. and Fan, G.
Cellular Signalling 79
: 109886.
March 2021
Identification of unique long non-coding RNAs as putative biomarkers for chromophobe renal cell carcinoma.
Wu, G., Xia, P., Yan, S., Chen, D., Xie, L. and Fan, G.
Personalized Medicine 18
(1): 9-19.
January 2021
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Wu, Y., Biswas, D., Usaite, I., Angelova, M., Boeing, S., Karasaki, T., Veeriah, S., Czyzewska-Khan, J., Morton, C., Joseph, M., Hessey, S., Reading, J., Georgiou, A., Al-Bakir, M., McGranahan, N., Jamal-Hanjani, M., Hackshaw, A., Quezada, S.A., Hayday, A.C. and Swanton, C.
Nature Cancer 3
(6): 696-709.
June 2022
Recombinant ovine atadenovirus induces a strong and sustained T cell response against the hepatitis C virus NS3 antigen in mice.
Wuest, T., Both, G.W., Prince, A.M., Hofmann, C. and Loeser, P.
Vaccine 22
(21-22): 2717-2721.
1 January 2004
Improved visualization and quantitative analysis of fluorescent membrane sterol in polarized hepatic cells.
Wuestner, D.
Journal of Microscopy 220
(1): 47-64.
1 October 2005
Mathematical analysis of hepatic high density lipoprotein transport based on quantitative imaging data.
Wuestner, D.
Journal of Biological Chemistry 280
(8): 6766-6779.
1 January 2005
Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells.
Wuestner, D., Mondal, M., Huang, A. and Maxfield, F.R.
Journal of Lipid Research 45
(3): 427-437.
1 March 2004
Direct observation of rapid internalization and intracellular transport of sterol by macrophage foam cells.
Wuestner, D., Mondal, M., Tabas, I. and Maxfield, F.R.
Traffic 6
(5): 396-412.
1 January 2005
Signal-dependent degradation of IkappaBalpha is mediated by an inducible destruction box that can be transferred to NF-kappaB, bcl-3 or p53.
Wulczyn, F.G., Krappmann, D. and Scheidereit, C.
Nucleic Acids Research 26
(7): 1724-1730.
1 April 1998
Alemtuzumab plus CHOP versus CHOP in elderly patients with peripheral T-cell lymphoma: the DSHNHL2006-1B/ACT-2 trial.
Wulf, G.G., Altmann, B., Ziepert, M., D'Amore, F., Held, G., Greil, R., Tournilhac, O., Relander, T., Viardot, A., Wilhelm, M., Wilhelm, C., Pezzutto, A., Zijlstra, J.M., Van Den Neste, E., Lugtenburg, P.J., Doorduijn, J.K., van Gelder, M., van Imhoff, G.W., Zettl, F., Braulke, F., Nickelsen, M., Glass, B., Rosenwald, A., Gaulard, P., Loeffler, M., Pfreundschuh, M., Schmitz, N. and Trümper, L.
Leukemia 35
(1): 143-155.
January 2021
Intrahepatically transplanted human cord blood cells reduce SW480 tumor growth in the presence of bispecific EpCAM/CD3 antibody.
Wulf-Goldenberg, A., Eckert, K. and Fichtner, I.
Cytotherapy 13
(1): 108-113.
January 2011
Cytokine-pretreatment of CD34(+) cord blood stem cells in vitro reduces long-term cell engraftment in NOD/SCID mice.
Wulf-Goldenberg, A., Eckert, K. and Fichtner, I.
European Journal of Cell Biology 87
(2): 69-80.
14 February 2008
Intrahepatic transplantation of CD34(+) cord blood stem cells into newborn and adult NOD/SCID mice induce differential organ engraftment.
Wulf-Goldenberg, A., Keil, M., Fichtner, I. and Eckert, K.
Tissue & Cell 44
(2): 80-86.
April 2012
Patient-derived xenografts from solid tumors (PDX) for models of metastasis.
Wulf-Goldenberg, A., Hoffmann, J., Becker, M., Brzezicha, B. and Walther, W.
Methods in Molecular Biology 2294
: 43-58.
2021
Optimization of the Gbeta1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization.
Wunderlich, M., Max, K.E., Roske, Y., Mueller, U., Heinemann, U. and Schmid, F.X.
Journal of Molecular Biology 373
(3): 775-784.
26 October 2007
Anton Sticker (1861-1944) und das Sticker-Sarkom des Hundes. Ein aktuelles Modell fuer infektioese Krebszellen [Anton Sticker (1861-1944) and the Sticker's sarcoma of dogs. A current model for infectious cancer cells].
Wunderlich, V.
Tieraerztliche Praxis Kleintiere 40
(6): 432-437.
2012
"Mit Papier, Bleistift und Rechenschieber." Der Krebsforscher Hermann Druckrey im Internierungslager Hammelburg (1946-1947) ["With paper, pencil, and slide rule." Cancer specialist Hermann Druckrey in internment camp Hammelburg (1946-1947)].
Wunderlich, V.
Medizinhistorisches Journal 43
(3-4): 327-343.
2008
"Zur Selbstreproduktion befaehigte Substanzen" als zellulaere Angriffsorte chemischer Cancerogene.
Wunderlich, V.
NTM International Journal of History & Ethics of Natural Sciences, Technology & Medicine 15
(4): 271-283.
October 2007
Arnold Graffi (1910-2006) : A pioneer of experimental cancer research.
Wunderlich, V. and Bielka, H.
Journal of Cancer Research and Clinical Oncology 132
(8): 483-485.
August 2006
Wegbereiter der modernen Krebsforschung: Theodor Boveri und Otto Warburg [Pioneers of modern cancer research: Theodor Boveri and Otto Warburg].
Wunderlich, V.
BIOspektrum 26
(6): 687-690.
November 2020
50 Jahre Reverse Transkriptase [50 years of reverse transcriptase].
Wunderlich, V.
BIOspektrum 26
(3): 343-344.
May 2020
Dosis und Wirkung in der Toxikologie: die Haber'sche Regel und Ableitungen.
Wunderlich, V.
BIOspektrum 25
(5): 584-585.
September 2019
Die Kenntnis der Krebskrankheit aus historischer Perspektive: Das beispiellose Werk des Berliner Arztes Jacob Wolff (1861–1938).
Wunderlich, V.
Acta Historica Leopoldina 74
: 221-247.
2019
Clinical outcome in patients with carcinoma of the esophagogastric junction treated with neoadjuvant radiochemotherapy or perioperative chemotherapy: a two-enter retrospective analysis.
Wundsam, H.V., Doleschal, B., Prommer, R., Venhoda, C., Schmitt, C., Petzer, A., Metz-Gercek, S. and Rumpold, H.
Oncology 98
(10): 706-713.
October 2020
Aberrant expression of and cell death induction by engagement of the MHC-II chaperone CD74 in anaplastic large cell lymphoma (ALCL).
Wurster, K.D., Costanza, M., Kreher, S., Glaser, S., Lamprecht, B., Schleussner, N., Anagnostopoulos, I., Hummel, M., Jöhrens, K., Stein, H., Molina, A., Diepstra, A., Gillissen, B., Köchert, K., Siebert, R., Merkel, O., Kenner, L., Janz, M. and Mathas, S.
Cancers 13
(19): 5012.
1 October 2021
Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.
Wurster, K.D., Hummel, F., Richter, J., Giefing, M., Hartmann, S., Hansmann, M.L., Kreher, S., Köchert, K., Krappmann, D., Klapper, W., Hummel, M., Wenzel, S.S., Lenz, G., Janz, M., Dörken, B., Siebert, R. and Mathas, S.
Leukemia 31
(3): 602-613.
March 2017
Rationale for using invasive thermometry for regional hyperthermia of pelvic tumors.
Wust, P., Gellermann, J., Harder, C., Tilly, W., Rau, B., Dinges, S., Schlag, P.M., Budach, V. and Felix, R.
International Journal of Radiation Oncology, Biology, Physics 41
(5): 1129-1137.
15 July 1998
Teilkoerperhyperthermie mit einem Radiofrequenz-Multiantennen-Applikator unter online Kontrolle in einem 1,5 T MR-Tomographen [Part-body hyperthermia with a radiofrequency multiantenna applicator under online control in a 1.5 T MR-tomograph].
Wust, P., Gellermann, J., Seebass, M., Faehling, H., Turner, P., Wlodarczyk, W., Nadobny, J., Rau, B., Hildebrandt, B., Oppelt, A., Schlag, P.M. and Felix, R.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 176
(3): 363-374.
1 March 2004
Non-thermal effects of radiofrequency electromagnetic fields.
Wust, P., Kortüm, B., Strauss, U., Nadobny, J., Zschaeck, S., Beck, M., Stein, U. and Ghadjar, P.
Scientific Reports 10
(1): 13488.
10 August 2020
Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.
Wust, P., Stein, U. and Ghadjar, P.
International Journal of Hyperthermia 38
(1): 715-731.
28 April 2021
Radiofrequency electromagnetic fields cause non-temperature-induced physical and biological effects in cancer cells.
Wust, P., Veltsista, P.D., Oberacker, E., Yavvari, P., Walther, W., Bengtsson, O., Sterner-Kock, A., Weinhart, M., Heyd, F., Grabowski, P., Stintzing, S., Heinrich, W., Stein, U. and Ghadjar, P.
Cancers 14
(21): 5349.
30 October 2022
Single-cell RNA-sequencing of RVFV infection.
Wyler, E.
Methods in Molecular Biology 2824
: 361-372.
August 2024
Pathogen dynamics and discovery of novel viruses and enzymes by deep nucleic acid sequencing of wastewater.
Wyler, E., Lauber, C., Manukyan, A., Deter, A., Quedenau, C., Teixeira Alves, L.G., Wylezich, C., Borodina, T., Seitz, S., Altmüller, J. and Landthaler, M.
Environment International 190
: 108875.
August 2024
Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single cell transcriptomics.
Wyler, E., Adler, J.M., Eschke, K., Teixeira Alves, G., Peidli, S., Pott, F., Kazmierski, J., Michalick, L., Kershaw, O., Bushe, J., Andreotti, S., Pennitz, P., Abdelgawad, A., Postmus, D., Goffinet, C., Kreye, J., Reincke, S.M., Prüss, H., Blüthgen, N., Gruber, A.D., Kuebler, W.M., Witzenrath, M., Landthaler, M., Nouailles, G. and Trimpert, J.
Molecular Therapy 30
(5): 1952-1965.
4 May 2022
Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program.
Wyler, E., Franke, V., Menegatti, J., Kocks, C., Boltengagen, A., Praktiknjo, S., Walch-Rückheim, B., Bosse, J., Rajewsky, N., Grässer, F., Akalin, A. and Landthaler, M.
Nature Communications 10
(1): 4878.
25 October 2019
Prävention von Infektionskrankheiten mit Abwasser [Prevention of Infectious Diseases with Wastewater].
Wyler, E. and Landthaler, M.
Arbeitsmedizin Sozialmedizin Umweltmedizin 58
(6): 381-384.
June 2023
Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.
Wyler, E., Menegatti, J., Franke, V., Kocks, C., Boltengagen, A., Hennig, T., Theil, K., Rutkowski, A., Ferrai, C., Baer, L., Kermas, L., Friedel, C., Rajewsky, N., Akalin, A., Dölken, L., Grässer, F. and Landthaler, M.
Genome Biology 18
(1): 209.
31 October 2017
Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E., Mösbauer, K., Franke, V., Diag, A., Gottula, L.T., Arsiè, R., Klironomos, F., Koppstein, D., Hönzke, K., Ayoub, S., Buccitelli, C., Hoffmann, K., Richter, A., Legnini, I., Ivanov, A., Mari, T., Del Giudice, S., Papies, J., Praktiknjo, S., Meyer, T.F., Müller, M.A., Niemeyer, D., Hocke, A., Selbach, M., Akalin, A., Rajewsky, N., Drosten, C. and Landthaler, M.
iScience 24
(3): 102151.
19 March 2021
Rattus norvegicus BN/SHR liver and heart left ventricle ribosomal RNA depleted directional RNA sequencing.
Wyler, E., van Heesch, S., Adami, E., Hubner, N. and Landthaler, M.
BMC Research Notes 10
(1): 395.
11 August 2017
Analysis of copy number variation in men with non-obstructive azoospermia.
Wyrwoll, M.J., Wabschke, R., Röpke, A., Wöste, M., Ruckert, C., Perrey, S., Rotte, N., Hardy, J., Astica, L., Lupianez, D.G., Wistuba, J., Westernströer, B., Schlatt, S., Berman, A.J., Müller, A.M., Kliesch, S., Yatsenko, A.N., Tüttelmann, F. and Friedrich, C.
Andrology 10
(8): 1593-1604.
November 2022
Surgery, surgical education and surgical diagnostic procedures in the digital era.
Wysocki, W.M., Moesta, K.T. and Schlag, P.M.
Medical Science Monitor 9
(3): RA69-RA75.
March 2003
hGBP1 coordinates chlamydia restriction and inflammasome activation through sequential GTP hydrolysis.
Xavier, A., Al-Zeer, M.A., Meyer, T.F. and Daumke, O.
Cell Reports 31
(7): 107667.
19 May 2020
CRNKL1 is a highly selective regulator of intron-retaining HIV-1 and cellular mRNAs.
Xiao, H., Wyler, E., Milek, M., Grewe, B., Kirchner, P., Ekici, A., Silva, A.B.O.V., Jungnickl, D., Full, F., Thomas, M., Landthaler, M., Ensser, A. and Überla, K.
mBio 12
(1): e02525-20.
19 January 2021
Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation.
Xiao, M.S., Zhang, B., Li, Y.S., Gao, Q., Sun, W. and Chen, W.
Molecular Systems Biology 12
(12): 890.
8 December 2016
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.
Xiong, E., Popp, O., Salomon, C., Mertins, P., Kocks, C., Rajewsky, K. and Chu, V.T.
Frontiers in Immunology 13
: 1083119.
5 January 2023
Deletion of beta-catenin impairs T cell development.
Xu, Y., Banerjee, D., Huelsken, J., Birchmeier, W. and Sen, J.M.
Nature Immunology 4
(12): 1177-1182.
1 January 2003
PDGFRA is a conserved HAND2 effector during early cardiac development.
Xu, Y., Gehlot, R., Capon, S.J., Albu, M., Gretz, J., Bloomekatz, J., Mattonet, K., Vucicevic, D., Talyan, S., Kikhi, K., Günther, S., Looso, M., Firulli, B.A., Sanda, M., Firulli, A.B., Lacadie, S.A., Yelon, D. and Stainier, D.Y.R.
Nature Cardiovascular Research 3
(12): 1531-1548.
December 2024
Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene transduced human T cells.
Xue, S.A., Gao, L., Hart, D., Gillmore, R., Qasim, W., Thrasher, A., Apperley, J., Engels, B., Uckert, W., Morris, E. and Stauss, H.J.
Blood 106
: 3062-3067.
14 July 2005
The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia.
Yalcin, A., Kovarbasic, M., Wehrle, J., Claus, R., Becker, H., Abdelkarim, M., Gaidzik, V.I., Schmidts, A., Wäsch, R., Pahl, H.L., Döhner, K., Bullinger, L., Duyster, J., Lübbert, M. and Hackanson, B.
Experimental Hematology 55
: 76-85.
November 2017
Overactivation of the NF-κB pathway impairs molar enamel formation.
Yamada, A., Kawasaki, M., Miake, Y., Yamada, Y., Blackburn, J., Kawasaki, K., Trakanant, S., Nagai, T., Nihara, J., Kudo, T., Meguro, F., Schmidt-Ullrich, R., Liu, B., Hu, Y., Page, A., Ramírez, Á., Sharpe, P.T., Maeda, T., Takagi, R. and Ohazama, A.
Oral Diseases 26
(7): 1513-1522.
October 2020
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Yan, S., Schöpe, P.C., Lewis, J., Putzker, K., Uhrig, U., Specker, E., von Kries, J.P., Lindemann, P., Omran, A., Sanchez-Ibarra, H.E., Unger, A., Zischinsky, M.L., Klebl, B., Walther, W., Nazaré, M., Kobelt, D. and Stein, U.
Biomedicine & Pharmacotherapy 168
: 115698.
December 2023
Independent and cooperative activation of chromosomal c-fos promoter by STAT3.
Yang, E., Lerner, L., Besser, D. and Darnell, J.E.
Journal of Biological Chemistry 278
(18): 15794-15799.
2 May 2003
Anti-proliferative efficacy of icariin on HepG2 hepatoma and its possible mechanism of action.
Yang, J.X., Fichtner, I., Becker, M., Lemm, M. and Wang, X.M.
American Journal of Chinese Medicine 37
(6): 1153-1165.
2009
Members of the fatty acid binding protein family are differentiation factors for the mammary gland.
Yang, Y., Spitzer, E., Kenney, N., Zschiesche, W., Li, M., Kromminga, A., Mueller, T., Spener, F., Lezius, A., Veerkamp, J.H., Smith, G.H., Salomon, D.S. and Grosse, R.
Journal of Cell Biology 127
(4): 1097-1109.
November 1994
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.
Yang, Y., Spitzer, E., Meyer, D., Sachs, M., Niemann, C., Hartmann, G., Weidner, K.M., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 131
(1): 215-226.
October 1995
Anisotropic fluctuations in the ribosome determine tRNA kinetics.
Yang, H., Noel, J.K. and Whitford, P.C.
Journal of Physical Chemistry B 121
(47): 10593-10601.
30 November 2017
Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
Yang, J.Y., Deng, X.Y., Li, Y.S., Ma, X.C., Feng, J.X., Yu, B., Chen, Y., Luo, Y.L., Wang, X., Chen, M.L., Fang, Z.X., Zheng, F.X., Li, Y.P., Zhong, Q., Kang, T.B., Song, L.B., Xu, R.H., Zeng, M.S., Chen, W., Zhang, H., Xie, W. and Gao, S.
Nature Communications 9
(1): 1165.
21 March 2018
ME2 promotes proneural–mesenchymal transition and lipogenesis in glioblastoma.
Yang, M., Chen, X., Zhang, J., Xiong, E., Wang, Q., Fang, W., Li, L., Fei, F. and Gong, A.
Frontiers in Oncology 11
: 715593.
23 July 2021
Depletion of aneuploid cells in human embryos and gastruloids.
Yang, M., Rito, T., Metzger, J., Naftaly, J., Soman, R., Hu, J., Albertini, D.F., Barad, D.H., Brivanlou, A.H. and Gleicher, N.
Nature Cell Biology 23
(4): 314-321.
April 2021
GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y., Du Jiang, P., Chao, B.N., Cagdas, D., Kubo, S., Balasubramaniyam, A., Zhang, Y., Shadur, B., NaserEddin, A., Folio, L.R., Schwarz, B., Bohrnsen, E., Zheng, L., Lynberg, M., Gottlieb, S., Leney-Greene, M.A., Park, A.Y., Tezcan, I., Akdogan, A., Gocmen, R., Onder, S., Rosenberg, A., Soilleux, E.J., Johnson, E., Jackson, P.K., Demeter, J., Chauvin, S.D., Paul, F., Selbach, M., Bulut, H., Clatworthy, M.R., Tuong, Z.K., Zhang, H., Stewart, B.J., Bosio, C.M., Stepensky, P., Clare, S., Ganesan, S., Pascall, J.C., Daumke, O., Butcher, G.W., McMichael, A.J., Simon, A.K. and Lenardo, M.J.
Journal of Experimental Medicine 219
(6): e20201405.
6 June 2022
Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection.
Yardımcı, G.G., Frank, C.L., Crawford, G.E. and Ohler, U.
Nucleic Acids Research 42
(19): 11865-11878.
29 October 2014
Chemokines CCL19 and CCL21 promote activation-induced cell death of antigen-responding T cells.
Yasuda, T., Kuwabara, T., Nakano, H., Aritomi, K., Onodera, T., Lipp, M., Takahama, Y. and Kakiuchi, T.
Blood 109
(2): 449-456.
15 January 2007
Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice.
Yasuda, T., Wirtz, T., Zhang, B., Wunderlich, T., Schmidt-Supprian, M., Sommermann, T. and Rajewsky, K.
Cold Spring Harbor Symposia on Quantitative Biology 78
: 259-263.
15 November 2013
Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT.
Yde, C.W., Frogne, T., Lykkesfeldt, A.E., Fichtner, I., Issinger, O.G. and Stenvang, J.
Cancer Letters 256
(2): 229-237.
28 October 2007
A cross-species comparison of X-chromosome inactivation in Eutheria.
Yen, Z.C., Meyer, I.M., Karalic, S. and Brown, C.J.
Genomics 90
(4): 453-463.
October 2007
Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.
Yilmaz, Z.B., Kofahl, B., Beaudette, P., Baum, K., Ipenberg, I., Weih, F., Wolf, J., Dittmar, G. and Scheidereit, C.
Cell Reports 9
(5): 1756-1769.
11 December 2014
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.
Yndestad, A., Finsen, A.V., Ueland, T., Husberg, C., Dahl, C.P., Oie, E., Vinge, L.E., Sjaastad, I., Sandanger, O., Ranheim, T., Dickstein, K., Kjekshus, J., Damas, J.K., Fiane, A.E., Hilfiker-Kleiner, D., Lipp, M., Gullestad, L., Christensen, G. and Aukrust, P.
PLoS ONE 7
(3): e33038.
12 March 2012
Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships.
Yokoyama, K.D., Ohler, U. and Wray, G.A.
Nucleic Acids Research 37
(13): e92.
July 2009
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids.
Yoney, A., Etoc, F., Ruzo, A., Carroll, T., Metzger, J.J., Martyn, I., Li, S., Kirst, C., Siggia, E.D. and Brivanlou, A.H.
eLife 7
: e3827.
13 November 2018
Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.
Yoshida, T., Iwata, T., Takai, Y., Birchmeier, W., Yamato, M. and Okano, T.
Genes to Cells 19
(11): 842-852.
November 2014
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.
Young, E., Noerenberg, D., Mansouri, L., Ljungström, V., Frick, M., Sutton, L.A., Blakemore, S.J., Galan-Sousa, J., Plevova, K., Baliakas, P., Rossi, D., Clifford, R., Roos-Weil, D., Navrkalova, V., Dörken, B., Schmitt, C.A., Smedby, K.E., Juliusson, G., Giacopelli, B., Blachly, J.S., Belessi, C., Panagiotidis, P., Chiorazzi, N., Davi, F., Langerak, A.W., Oscier, D., Schuh, A., Gaidano, G., Ghia, P., Xu, W., Fan, L., Bernard, O.A., Nguyen-Khac, F., Rassenti, L., Li, J., Kipps, T.J., Stamatopoulos, K., Pospisilova, S., Zenz, T., Oakes, C.C., Strefford, J.C., Rosenquist, R. and Damm, F.
Leukemia 31
(7): 1547-1554.
July 2017
Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging.
Young, K., Eudy, E., Bell, R., Loberg, M.A., Stearns, T., Sharma, D., Velten, L., Haas, S., Filippi, M.D. and Trowbridge, J.J.
Cell Stem Cell 28
(8): 1473-1482.
5 August 2021
Analysis of single-cell transcriptome data in drosophila.
Yousefian, S., Musillo, M.J. and Bageritz, J.
Methods in Molecular Biology 2540
(3): 93-111.
19 August 2022
The role of Axin2 in calvarial morphogenesis and craniosynostosis.
Yu, H.M., Jerchow, B., Sheu, T.J., Liu, B., Costantini, F., Puzas, J.E., Birchmeier, W. and Hsu, W.
Development 132
(8): 1995-2005.
1 January 2005
Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.
Yu, J., Valerius, M.T., Duah, M., Staser, K., Hansard, J.K., Guo, J.J., McMahon, J., Vaughan, J., Faria, D., Georgas, K., Rumballe, B., Ren, Q., Krautzberger, A.M., Junker, J.P., Thiagarajan, R.D., Machanick, P., Gray, P.A., van Oudenaarden, A., Rowitch, D.H., Stiles, C.D., Ma, Q., Grimmond, S.M., Bailey, T.L., Little, M.H. and McMahon, A.P.
Development 139
(10): 1863-1873.
May 2012
Epigenetic co-deregulation of EZH2/TET1 is a senescence-countering, actionable vulnerability in triple-negative breast cancer.
Yu, Y., Qi, J., Xiong, J., Jiang, L., Cui, D., He, J., Chen, P., Li, L., Wu, C., Ma, T., Shao, S., Wang, J., Yu, D., Zhou, B., Huang, D., Schmitt, C.A. and Tao, R.
Theranostics 9
(3): 761-777.
24 January 2019
Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma.
Yu, Y., Schleich, K., Yue, B., Ji, S., Lohneis, P., Kemper, K., Silvis, M.S., Qutob, N., van Rooijen, E., Werner-Klein, M., Li, L., Dhawan, D., Meierjohann, S., Reimann, M., Elkahloun, A., Treitschke, S., Dörken, B., Speck, C., Mallette, F.A., Zon, L.I., Holmen, S.L., Peeper, D.S., Samuels, Y., Schmitt, C.A. and Lee, S.
Cancer Cell 33
(2): 322-336.
12 February 2018
Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling.
Yuan, Y., Failmezger, H., Rueda, O.M., Ali, H.R., Graef, S., Chin, S.F., Schwarz, R.F., Curtis, C., Dunning, M.J., Bardwell, H., Johnson, N., Doyle, S., Turashvili, G., Provenzano, E., Aparicio, S., Caldas, C. and Markowetz, F.
Science Translational Medicine 4
(157): 157ra143.
24 October 2012
Fatal immune haemolysis due to antibodies to individual metabolites of 5-fluorouracil.
Yuerek, S., Riess, H., Kreher, S., Doerken, B. and Salama, A.
Transfusion Medicine 20
(4): 265-268.
1 August 2010
Efficient gene editing of human induced pluripotent stem cells using CRISPR/Cas9.
Yumlu, S., Bashir, S., Stumm, J. and Kühn, R.
Methods in Molecular Biology 1961
: 137-151.
2019
Gene editing and clonal isolation of human induced pluripotent stem cells using CRISPR/Cas9.
Yumlu, S., Stumm, J., Bashir, S., Dreyer, A.K., Lisowski, P., Danner, E. and Kühn, R.
Methods 121-122
: 29-44.
15 May 2017
Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia.
Yun, H., Damm, F., Yap, D., Schwarzer, A., Chaturvedi, A., Jyotsana, N., Lübbert, M., Bullinger, L., Döhner, K., Geffers, R., Aparicio, S., Humphries, R.K., Ganser, A. and Heuser, M.
Haematologica 99
(9): 1456-1464.
September 2014
Grainyhead-like 2 deficiency and kidney cyst growth in a mouse model.
Yurtdas, Z.Y., Kilic, E., Boor, P., Wyler, E., Landthaler, M., Jung, K. and Schmidt-Ott, K.M.
Journal of the American Society of Nephrology 35
(7): 838-853.
July 2024
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf, R.Z., Saez, B., Sharda, A., van Gastel, N., Yu, V.W.C., Baryawno, N., Scadden, E.W., Acharya, S., Chattophadhyay, S., Huang, C., Viswanathan, V., S'aulis, D., Cobert, J., Sykes, D.B., Keibler, M.A., Das, S., Hutchinson, J.N., Churchill, M., Mukherjee, S., Lee, D., Mercier, F., Doench, J., Bullinger, L., Logan, D.J., Schreiber, S., Stephanopoulos, G., Rizzo, W.B. and Scadden, D.T.
Blood 136
(11): 1303-1316.
10 September 2020
Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta.
Yvernogeau, L., Klaus, A., Maas, J., Morin-Poulard, I., Weijts, B., Schulte-Merker, S., Berezikov, E., Junker, J.P. and Robin, C.
Blood 136
(7): 831-844.
13 August 2020
Influence of static and dynamic bends on the birefringence decay profile of RNA helices: Brownian dynamics simulations.
Zacharias, M. and Hagerman, P.J.
Biophysical Journal 73
(1): 318-332.
July 1997
Conformational deformability of RNA: A harmonic mode analysis.
Zacharias, M. and Sklenar, H.
Biophysical Journal 78
(5): 2528-2542.
May 2000
Analysis of the stability of looped-out and stacked-in conformations of an adenine bulge in DNA using a continuum model for solvent and ions.
Zacharias, M. and Sklenar, H.
Biophysical Journal 73
(6): 2990-3003.
December 1997
Integrated phosphoproteome and transcriptome analysis reveals Chlamydia-induced epithelial-to-mesenchymal transition in host cells.
Zadora, P.K., Chumduri, C., Imami, K., Berger, H., Mi, Y., Selbach, M., Meyer, T.F. and Gurumurthy, R.K.
Cell Reports 26
(5): 1286-1302.
29 January 2019
Cardiac magnetic resonance monitors reversible and irreversible myocardial injury in myocarditis.
Zagrosek, A., Abdel-Aty, H., Boye, P., Wassmuth, R., Messroghli, D., Utz, W., Rudolph, A., Bohl, S., Dietz, R. and Schulz-Menger, J.
JACC: Cardiovascular Imaging 2
(2): 131-138.
February 2009
Non-invasive metastasis prognosis from plasma metabolites in stage II colorectal cancer patients: the DACHS study.
Zaimenko, I., Jaeger, C., Brenner, H., Chang-Claude, J., Hoffmeister, M., Grötzinger, C., Detjen, K., Burock, S., Schmitt, C.A., Stein, U. and Lisec, J.
International Journal of Cancer 145
(1): 221-231.
1 July 2019
Analysis of NPM1 splice variants reveals differential expression patterns of prognostic value in acute myeloid leukemia.
Zajac, M., Dolnik, A., Stasiak, G., Zaleska, J., Kielbus, M., Czapinski, J., Schunn, M., Correa, S.C., Glodkowska-Mrowka, E., Sundaram, R.C., Jankowska-Lecka, O., Schlenk, R.F., Döhner, H., Döhner, K., Stepulak, A., Bullinger, L. and Giannopoulos, K.
Oncotarget 8
(56): 95163-95175.
10 November 2017
Response to anti-SARS-CoV-2 mRNA vaccines in multiple myeloma and chronic lymphocytic leukemia patients.
Zaleska, J., Kwasnik, P., Paziewska, M., Purkot, Jo., Szabelak, A., Jurek, M., Masny, N., Dziatkiewicz, I., Pronobis-Szczylik, B., Piebiak, A., Szymczyk, A., Jarosz-Chudzik, K., Bolkun, L., Kozlowska, K., Piszcz, J., Subocz, E., Halka, J., Bator, M., Kalicinska, E., Wrobel, T., Usnarska-Zubkiewicz, L., Rybka, J., Deren-Wagemann, I., Szyca-Smieszniak, M., Dybko, J., Hus, I., Pula, B., Cichocka, E., Rymko, M., Zdunczyk, D., Ziarkiewicz, M., Basak, G.W., Bullinger, L. and Giannopoulos, K.
International Journal of Cancer 15
(4): 705-712.
15 February 2023
MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.
Zaltsman, Y., Shachnai, L., Yivgi-Ohana, N., Schwarz, M., Maryanovich, M., Houtkooper, R.H., Vaz, F.M., De Leonardis, F., Fiermonte, G., Palmieri, F., Gillissen, B., Daniel, P.T., Jimenez, E., Walsh, S., Koehler, C.M., Roy, S.S., Walter, L., Hajnoczky, G. and Gross, A.
Nature Cell Biology 12
(6): 553-562.
June 2010
ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration.
Zandi, S., Nakao, S., Chun, K.H., Fiorina, P., Sun, D., Arita, R., Zhao, M., Kim, E., Schueller, O., Campbell, S., Taher, M., Melhorn, M.I., Schering, A., Gatti, F., Tezza, S., Xie, F., Vergani, A., Yoshida, S., Ishikawa, K., Yamaguchi, M., Sasaki, F., Schmidt-Ullrich, R., Hata, Y., Enaida, H., Yuzawa, M., Yokomizo, T., Kim, Y.B., Sweetnam, P., Ishibashi, T. and Hafezi-Moghadam, A.
Cell Reports 10
(7): 1173-1186.
24 February 2015
Concurrent inhibition of PI3-Kinase and mTOR induces cell death in diffuse large B cell lymphomas, a mechanism involving down regulation of Mcl-1.
Zang, C., Eucker, J., Liu, H., Mueller, A., Possinger, K. and Scholz, C.W.
Cancer Letters 339
(2): 288-297.
10 October 2013
Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.
Zantl, N., Weirich, G., Zall, H., Seiffert, B.M., Fischer, S.F., Kirschnek, S., Hartmann, C., Fritsch, R.M., Gillissen, B., Daniel, P.T. and Haecker, G.
Oncogene 26
(49): 7038-7048.
25 October 2007
RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A., van den Bruck, D., Ciolli Mattioli, C., Franke, V., Imami, K., McShane, E., Moreno-Estelles, M., Calviello, L., Filipchyk, A., Peguero-Sanchez, E., Müller, T., Woehler, A., Birchmeier, C., Merino, E., Rajewsky, N., Ohler, U., Mazzoni, E.O., Selbach, M., Akalin, A. and Chekulaeva, M.
Nature Communications 8
(1): 583.
19 September 2017
Repression of transcriptional activity of C/EBPα by E2F-DP complexes.
Zaragoza, K., Bégay, V., Schuetz, A., Heinemann, U. and Leutz, A.
Molecular and Cellular Biology 30
(9): 2293-2304.
May 2010
The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis.
Zatula, N., Wiese, M., Bunzendahl, J., Birchmeier, W., Perske, C., Bleckmann, A. and Brembeck, F.H.
Oncotarget 5
(16): 6770-6787.
30 August 2014
The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition.
Zayed, H., Izsvak, Z., Khare, D., Heinemann, U. and Ivics, Z.
Nucleic Acids Research 31
(9): 2313-2322.
1 May 2003
Monogenic variants in dystonia: an exome-wide sequencing study.
Zech, M., Jech, R., Boesch, S., Škorvánek, M., Weber, S., Wagner, M., Zhao, C., Jochim, A., Necpál, J., Dincer, Y., Vill, K., Distelmaier, F., Stoklosa, M., Krenn, M., Grunwald, S., Bock-Bierbaum, T., Fečíková, A., Havránková, P., Roth, J., Příhodová, I., Adamovičová, M., Ulmanová, O., Bechyně, K., Danhofer, P., Veselý, B., Haň, V., Pavelekova, P., Gdovinová, Z., Mantel, T., Meindl, T., Sitzberger, A., Schröder, S., Blaschek, A., Roser, T., Bonfert, M.V., Haberlandt, E., Plecko, B., Leineweber, B., Berweck, S., Herberhold, T., Langguth, B., Švantnerová, J., Minár, M., Ramos-Rivera, G.A., Wojcik, M.H., Pajusalu, S., Õunap, K., Schatz, U.A., Pölsler, L., Milenkovic, I., Laccone, F., Pilshofer, V., Colombo, R., Patzer, S., Iuso, A., Vera, J., Troncoso, M., Fang, F., Prokisch, H., Wilbert, F., Eckenweiler, M., Graf, E., Westphal, D.S., Riedhammer, K.M., Brunet, T., Alhaddad, B., Berutti, R., Strom, T.M., Hecht, M., Baumann, M., Wolf, M., Telegrafi, A., Person, R.E., Zamora, F.M., Henderson, L.B., Weise, D., Musacchio, T., Volkmann, J., Szuto, A., Becker, J., Cremer, K., Sycha, T., Zimprich, F., Kraus, V., Makowski, C., Gonzalez-Alegre, P., Bardakjian, T.M., Ozelius, L.J., Vetro, A., Guerrini, R., Maier, E., Borggraefe, I., Kuster, A., Wortmann, S.B., Hackenberg, A., Steinfeld, R., Assmann, B., Staufner, C., Opladen, T., Růžička, E., Cohn, R.D., Dyment, D., Chung, W.K., Engels, H., Ceballos-Baumann, A., Ploski, R., Daumke, O., Haslinger, B., Mall, V., Oexle, K. and Winkelmann, J.
Lancet Neurology 19
(11): 908-918.
November 2020
Deciphering the function of signaling pathways by tissue specific gene modification in mice.
Zechner, D., Soshnikova, N. and Birchmeier, W.
Zellbiologie Aktuell 30
(1): 6-8.
January 2004
Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Zechner, D., Muller, T., Wende, H., Walther, I., Taketo, M.M., Crenshaw, E.B., Treier, M., Birchmeier, W. and Birchmeier, C.
Developmental Biology 303
(1): 181-190.
1 March 2007
Recognition of T-rich single-stranded DNA by the cold shock protein Bs-CspB in solution.
Zeeb, M., Max, K.E.A., Weininger, U., Loew, C., Sticht, H. and Balbach, J.
Nucleic Acids Research 34
(16): 4561-4571.
2006
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender, A., Huang, J., Györfi, A.H., Matei, A.E., Trinh-Minh, T., Xu, X., Li, Y.N., Chen, C.W., Lin, J., Dees, C., Beyer, C., Gelse, K., Zhang, Z.Y., Bergmann, C., Ramming, A., Birchmeier, W., Distler, O., Schett, G. and Distler, J.H.W.
Nature Communications 9
(1): 3259.
14 August 2018
Long noncoding RNA TYKRIL plays a role in pulmonary hypertension via the p53-mediated regulation of PDGFRβ.
Zehendner, C.M., Valasarajan, C., Werner, A., Boeckel, J.N., Bischoff, F.C., John, D., Weirick, T., Glaser, S.F., Rossbach, O., Jaé, N., Demolli, S., Khassafi, F., Yuan, K., de Jesus Perez, V.A., Michalik, K.M., Chen, W., Seeger, W., Guenther, A., Wasnick, R.M., Uchida, S., Zeiher, A.M., Dimmeler, S. and Pullamsetti, S.S.
American Journal of Respiratory and Critical Care Medicine 202
(10): 1445-1457.
15 November 2020
Identification of tumor-associated protein variants during rat hepatocarcinogenesis. Aldose reductase.
Zeindl-Eberhart, E., Jungblut, P., Otto, A. and Rabes, H.M.
Journal of Biological Chemistry 269
(20): 14589-14594.
20 May 1994
Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multi-center survey.
Zeiser, R., Burchert, A., Lengerke, C., Verbeek, M., Maas-Bauer, K., Metzelder, S.K., Spoerl, S., Ditschkowski, M., Ecsedi, M., Sockel, K., Ayuk, F., Ajib, S., de Fontbrune, F.S., Na, I.K., Penter, L., Holtick, U., Wolf, D., Schuler, E., Meyer, E., Apostolova, P., Bertz, H., Marks, R., Lübbert, M., Wäsch, R., Scheid, C., Stölzel, F., Ordemann, R., Bug, G., Kobbe, G., Negrin, R., Brune, M., Spyridonidis, A., Schmitt-Gräff, A., van der Velden, W., Huls, G., Mielke, S., Grigoleit, G.U., Kuball, J., Flynn, R., Ihorst, G., Du, J., Blazar, B.R., Arnold, R., Kröger, N., Passweg, J., Halter, J., Socie, G., Beelen, D., Peschel, C., Neubauer, A., Finke, J., Duyster, J. and von Bubnoff, N.
Leukemia 29
(10): 2062-2068.
October 2015
Physical properties and pharmacological activity in vitro and in vivo of optimised liposomes prepared from a new cancerostatic alkylphospholipid.
Zeisig, R., Arndt, D., Stahn, R. and Fichtner, I.
Biochimica et Biophysica Acta - Biomembranes 1414
(1-2): 238-248.
11 November 1998
Increase in fluidity in the membrane of MT3 breast cancer cells correlates with enhanced cell adhesion in vitro and increased lung metastasis in NOD/SCID mice.
Zeisig, R., Koklic, T., Wiesner, B., Fichtner, I. and Sentjurc, M.
Archives of Biochemistry and Biophysics 459
(1): 98-106.
1 March 2007
Lipoplexes with alkylphospholipid as new helper lipid for efficient in vitro and in vivo gene transfer in tumor therapy.
Zeisig, R., Ress, A., Fichtner, I. and Walther, W.
Cancer Gene Therapy 10
(4): 302-311.
April 2003
Reduction of tamoxifen resistance in human breast carcinomas by tamoxifen-containing liposomes in vivo.
Zeisig, R., Rueckerl, D. and Fichtner, I.
Anti-Cancer Drugs 15
(7): 707-714.
1 August 2004
Effect of sialyl Lewis X-glycoliposomes on the inhibition of E-selectin-mediated tumour cell adhesion in vitro.
Zeisig, R., Stahn, R., Wenzel, K., Behrens, D. and Fichtner, I.
Biochimica et Biophysica Acta - Biomembranes 1660
(1): 31-40.
28 January 2004
Liposomal 4-hydroxy-tamoxifen: effect on cellular uptake and resulting cytotoxicity in drug resistant breast cancer cells in vitro.
Zeisig, R., Teppke, A.D., Behrens, D. and Fichtner, I.
Breast Cancer Research and Treatment 87
(3): 245-254.
1 January 2004
SASH1: a candidate tumor suppressor gene on chromosome 6q24.3 is downregulated in breast cancer.
Zeller, C., Hinzmann, B., Seitz, S., Prokoph, H., Burkhard-Goettges, E., Fischer, J., Jandrig, B., Schwarz, L.E., Rosenthal, A. and Scherneck, S.
Oncogene 22
(19): 2972-2983.
15 May 2003
Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome.
Zemojtel, T., Koehler, S., Mackenroth, L., Jaeger, M., Hecht, J., Krawitz, P., Graul-Neumann, L., Doelken, S., Ehmke, N., Spielmann, M., Oien, N.C., Schweiger, M.R., Krueger, U., Frommer, G., Fischer, B., Kornak, U., Floettmann, R., Ardeshirdavani, A., Moreau, Y., Lewis, S.E., Haendel, M., Smedley, D., Horn, D., Mundlos, S. and Robinson, P.N.
Science Translational Medicine 6
(252): 252ra123.
3 September 2014
Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.
Zhai, Y., Singh, P., Dolnik, A., Brazda, P., Atlasy, N., Del Gaudio, N., Döhner, K., Döhner, H., Minucci, S., Martens, J., Altucci, L., Megchelenbrink, W., Bullinger, L. and Stunnenberg, H.G.
Molecular Cancer 21
(1): 166.
19 August 2022
Construct validity testing of a laparoscopic surgery simulator (Lap Mentor((R))) : Evaluation of surgical skill with a virtual laparoscopic training simulator.
Zhang, A., Huenerbein, M., Dai, Y., Schlag, P.M. and Beller, S.
Surgical Endoscopy 22
(6): 1440-1444.
June 2008
An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression.
Zhang, B., Calado, D.P., Wang, Z., Froehler, S., Koechert, K., Qian, Y., Koralov, S.B., Schmidt-Supprian, M., Sasaki, Y., Unitt, C., Rodig, S., Chen, W., Dalla-Favera, R., Alt, F.W., Pasqualucci, L. and Rajewsky, K.
Cell Reports 11
(5): 715-726.
5 May 2015
Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery.
Zhang, G., Hoersch, S., Amsterdam, A., Whittaker, C.A., Beert, E., Catchen, J.M., Farrington, S., Postlethwait, J.H., Legius, E., Hopkins, N. and Lees, J.A.
PLoS Genetics 9
(8): e1003734.
August 2013
Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.
Zhang, G., Hoersch, S., Amsterdam, A., Whittaker, C.A., Lees, J.A. and Hopkins, N.
Proceedings of the National Academy of Sciences of the United States of America 107
(39): 16940-16945.
28 September 2010
Fibroblast-specific protein 1/S100A4-positive cells prevent carcinoma through collagen production and encapsulation of carcinogens.
Zhang, J, Chen, L, Liu, X, Kammertoens, T., Blankenstein, T. and Qin, Z.
Cancer Research 73
(9): 2770-2781.
1 May 2013
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.
Zhang, Y., Andl, T., Yang, S.H., Teta, M., Liu, F., Seykora, J.T., Tobias, J.W., Piccolo, S., Schmidt-Ullrich, R., Nagy, A., Taketo, M.M., Dlugosz, A.A. and Millar, S.E.
Development 135
(12): 2161-2172.
June 2008
Reciprocal requirements for EDA/EDAR/NF-κB and Wnt/β-catenin signaling pathways in hair follicle induction.
Zhang, Y., Tomann, P., Andl, T., Gallant, N.M., Huelsken, J., Jerchow, B., Birchmeier, W., Paus, R., Piccolo, S., Mikkola, M.L., Morrisey, E.E., Overbeek, P.A., Scheidereit, C., Millar, S.E. and Schmidt-Ullrich, R.
Developmental Cell 17
(1): 49-61.
21 July 2009
Immune surveillance and therapy of lymphomas driven by Epstein-Barr-Virus protein LMP1 in a mouse model.
Zhang, B., Kracker, S., Yasuda, T., Casola, S., Vanneman, M., Hömig-Hölzel, C., Wang, Z., Derudder, E., Li, S., Chakraborty, T., Cotter, S.E., Koyama, S., Currie, T., Freeman, G.J., Kutok, J.L., Rodig, S.J., Dranoff, G. and Rajewsky, K.
Cell 148
(4): 739-751.
17 February 2012
Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19.
Zhang, B., Zhang, Z., Koeken, V.A.C.M., Kumar, S., Aillaud, M., Tsay, H.C., Liu, Z., Kraft, A.R.M., Soon, C.F., Odak, I., Bošnjak, B., Vlot, A., Swertz, M.A., Ohler, U., Geffers, R., Illig, T., Huehn, J., Saliba, A.E., Sander, L.E., Förster, R., Xu, C.J., Cornberg, M., Schulte, L.N. and Li, Y.
Cell Genomics 3
(2): 100232.
8 February 2023
Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex.
Zhang, G., Kruse, T., Guasch Boldú, C., Garvanska, D.H., Coscia, F., Mann, M., Barisic, M. and Nilsson, J.
EMBO Journal 38
(7): e100977.
1 April 2019
Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence.
Zhang, H., Alsaleh, G., Feltham, J., Sun, Y., Napolitano, G., Riffelmacher, T., Charles, P., Frau, L., Hublitz, P., Yu, Z., Mohammed, S., Ballabio, A., Balabanov, S., Mellor, J. and Simon, A.K.
Molecular Cell 76
(1): 110-125.
3 October 2019
LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cells.
Zhang, J., Sommermann, T., Li, X., Gieselmann, L., de la Rosa, K., Stecklum, M., Klein, F., Kocks, C. and Rajewsky, K.
Frontiers in Immunology 14
: 1331730.
19 December 2023
Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
Zhang, L., Wirth, M., Patra, U., Stroh, J., Isaakidis, K., Rieger, L., Kossatz, S., Milanovic, M., Zang, C., Demel, U., Keiten-Schmitz, J., Wagner, K., Steiger, K., Rad, R., Bassermann, F., Müller, S., Keller, U. and Schick, M.
EMBO Molecular Medicine 15
(9): e16431.
September 2023
DNA base flipping analytical pipeline.
Zhang, P., Hastert, F.D., Ludwig, A.K., Breitwieser, K., Hofstätter, M. and Cardoso, M.C.
Biology Methods & Protocols 2
(1): bpx010.
11 August 2017
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Zhang, Y., Chen, F., Fonseca, N.A., He, Y., Fujita, M., Nakagawa, H., Zhang, Z., Brazma, A. and Creighton, C.J.
Nature Communications 11
(1): 736.
5 February 2020
Asymmetric opening of the homopentameric 5-HT(3A) serotonin receptor in lipid bilayers.
Zhang, Y., Dijkman, P.M., Zou, R., Zandl-Lang, M., Sanchez, R.M., Eckhardt-Strelau, L., Köfeler, H., Vogel, H., Yuan, S. and Kudryashev, M.
Nature Communications 12
(1): 1074.
16 February 2021
Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells.
Zhang, Y., Lahmann, I., Baum, K., Shimojo, H., Mourikis, P., Wolf, J., Kageyama, R. and Birchmeier, C.
Nature Communications 12
(1): 1318.
26 February 2021
Tumor necrosis factor receptor 2-mediated tumor suppression is nitric oxide dependent and involves angiostasis.
Zhao, X., Mohaupt, M., Jiang, J., Liu, S., Li, B. and Qin, Z.
Cancer Research 67
(9): 4443-4450.
1 May 2007
Salmonella typhimurium infection triggers dendritic cells and macrophages to adopt distinct migration patterns in vivo.
Zhao, C., Wood, M.W., Galyov, E.E., Höpken, U.E., Lipp, M., Bodmer, H.C., Tough, D.F. and Carter, R.W.
European Journal of Immunology 36
(11): 2939-2950.
November 2006
A simple pressure-assisted method for MicroED specimen preparation.
Zhao, J., Xu, H., Lebrette, H., Carroni, M., Taberman, H., Högbom, M. and Zou, X.
Nature Communications 12
(1): 5036.
19 August 2021
Delayed allogeneic skin graft rejection in CD26-deficient mice.
Zhao, X., Zhang, K., Daniel, P., Wisbrun, N., Fuchs, H. and Fan, H.
Cellular and Molecular Immunology 16
(6): 557-567.
June 2019
A novel predictor tool of biochemical recurrence after radical prostatectomy based on a five-microRNA tissue signature.
Zhao, Z., Weickmann, S., Jung, M., Lein, M., Kilic, E., Stephan, C., Erbersdobler, A., Fendler, A. and Jung, K.
Cancers 11
(10): 1603.
21 October 2019
The primary transcriptome of barley chloroplasts: numerous noncoding RNAs and the dominating role of the plastid-encoded RNA polymerase.
Zhelyazkova, P., Sharma, C.M., Foerstner, K.U., Liere, K., Vogel, J. and Boerner, T.
Plant Cell 24
(1): 123-136.
January 2012
RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints.
Zhong, Y., Karaletsos, T., Drewe, P., Sreedharan, V.T., Kuo, D., Singh, K., Wendel, H.G. and Raetsch, G.
Bioinformatics 33
(1): 139-141.
1 January 2017
T cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing.
Zhou, Q., Schneider, I.C., Edes, I., Honegger, A., Bach, P., Schoenfeld, K., Schambach, A., Wels, W.S., Kneissl, S., Uckert, W. and Buchholz, C.J.
Blood 120
(22): 4334-4342.
22 November 2012
Transient RNA structure features are evolutionarily conserved and can be computationally predicted.
Zhu, J.Y.A., Steif, A., Proctor, J.R. and Meyer, I.M.
Nucleic Acids Research 41
(12): 6273-6285.
8 July 2013
Ribosomal protein S7 is both a regulator and a substrate of MDM2.
Zhu, Y., Poyurovsky, M.V., Li, Y., Biderman, L., Stahl, J., Jacq, X. and Prives, C.
Molecular Cell 35
(3): 316-326.
14 August 2009
Four RNA families with functional transient structures.
Zhu, J.Y. and Meyer, I.M.
RNA Biology 12
(1): 5-20.
2015
The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer.
Zhu, Q., Fang, L., Heuberger, J., Kranz, A., Schipper, J., Scheckenbach, K., Oliveira Vidal, R., Sunaga-Franze, D.Y., Müller, M., Wulf-Goldenberg, A., Sauer, S. and Birchmeier, W.
Cell Reports 26
(2): 415-428.
8 January 2019
DCGG: drug combination prediction using GNN and GAE.
Ziaee, S.S., Rahmani, H., Tabatabaei, M., Vlot, A.H.C. and Bender, A.
Progress in Artificial Intelligence 13
: 17-30.
March 2024
Distinct roles of the two isoforms of the dynamin-like GTPase Mgm1 in mitochondrial fusion.
Zick, M., Duvezin-Caubet, S., Schaefer, A., Vogel, F., Neupert, W. and Reichert, A.S.
FEBS Letters 583
(13): 2237-2243.
7 July 2009
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Zidek, L.M., Ackermann, T., Hartleben, G., Eichwald, S., Kortman, G., Kiehntopf, M., Leutz, A., Sonenberg, N., Wang, Z.Q., von Maltzahn, J., Müller, C. and Calkhoven, C.F.
EMBO Reports 16
(08): 1022-1036.
August 2015
Dissection of open chromatin domain formation by site specific recombination in Drosophila.
Zielke, T. and Saumweber, H.
Journal of Cell Science 127
(Pt 10): 2365-2375.
15 May 2014
High-resolution in situ hybridization analysis on the chromosomal interval 61C7-61C8 of Drosophila melanogaster reveals interbands as open chromatin domains.
Zielke, T., Glotov, A. and Saumweber, H.
Chromosoma 125
(3): 423-435.
June 2016
Linkage analysis in German breast cancer families with early onset of the disease, using highly polymorphic markers from the chromosome 17q11-q24 region.
Zimmermann, W., Bender, E., Rohde, K., Reis, A., Wiseman, R., Futreal, A., Krause, H., Prokoph, H., Werner, S. and Scherneck, S.
American Journal of Human Genetics 52
(4): 789-791.
April 1993
Generation of human iPSC-derived neural progenitor cells (NPCs) as drug discovery model for neurological and mitochondrial disorders.
Zink, A., Lisowski, P. and Prigione, A.
Bio-protocol 11
(5): e3939.
5 March 2021
HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U., Milek, M., Minia, I., Vieira-Vieira, C.H., Müller, S., Mastrobuoni, G., Hazapis, O.G., Del Giudice, S., Schwefel, D., Bley, N., Voigt, F., Chao, J.A., Kempa, S., Hüttelmaier, S., Selbach, M. and Landthaler, M.
Nature Communications 13
(1): 2727.
18 May 2022
Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization of the molecular subtype.
Zinnall, U., Weyerer, V., Compérat, E., Camparo, P., Gaisa, N.T., Knuechel-Clarke, R., Perren, A., Lugli, A., Toma, M., Baretton, G., Kristiansen, G., Wirtz, R.M., Cheng, L., Wullich, B., Stoehr, R., Hartmann, A. and Bertz, S.
Human Pathology 80
: 55-64.
October 2018
Sinusoidal obstruction syndrome following myeloablative therapy and tranexamic acid treatment for hemorrhage in two patients with neuroblastoma.
Zirngibl, F., Flemmig, C., Lang, P., Künkele, A., Eggert, A., Schulte, J.H. and Deubzer, H.E.
Children 7
(11): 198.
November 2020
The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G., Vanzo, R., Amitash, S., Martín-Doncel, E., Coscia, F., Mund, A., Lerdrup, M., Benada, J., Boos, D. and Toledo, L.
Molecular Cell 82
(18): 3350-3365.
15 September 2022
Regionale Verbuende in der Onkologie. Von der Idee zur Gemeinschaft [Regional associations in oncology. From the concept to a community].
Zuenkeler, M. and Schlag, P.M.
Onkologe 15
(11): 1070-1077.
November 2009
Meiosis onset is postponed to postnatal stages during ovotestis development in female moles.
Zurita, F., Carmona, F.D., Lupianez, D.G., Barrionuevo, F.J., Guioli, S., Burgos, M. and Jimenez, R.
Sexual Development 1
(1): 66-76.
2007
Smoking-associated gene expression alterations in nasal epithelium reveal immune impairment linked to lung cancer risk.
de Biase, M.S., Massip, F., Wei, T.T., Giorgi, F.M., Stark, R., Stone, A., Gladwell, A., O'Reilly, M., Schütte, D., de Santiago, I., Meyer, K.B., Markowetz, F., Ponder, B.A.J., Rintoul, R.C. and Schwarz, R.F.
Genome Medicine 16
(1): 54.
8 April 2024
Tumour mutational burden and survival with molecularly matched therapy.
de Bortoli, T., Benary, M., Horak, P., Lamping, M., Stintzing, S., Tinhofer, I., Leyvraz, S., Schäfer, R., Klauschen, F., Keller, U., Stenzinger, A., Fröhling, S., Kurzrock, R., Keilholz, U., Rieke, D.T. and Jelas, I.
European Journal of Cancer 190
: 112925.
September 2023
Impaired effector memory T-cell regulation facilitates graft versus host disease in CCR7-deficient bone marrow transplant chimeras.
de Jager, S.C., Cante-Barrett, K., Bot, I., Husberg, C., van Puijvelde, G.H., van Santbrink, P.J., Yndestad, A., van den Oever, J.M., Kuiper, J., van Berkel, T.J., Lipp, M., Zwaginga, J.J., Fibbe, W.E., Aukrust, P. and Biessen, E.A.
Transplantation 88
(5): 631-639.
15 September 2009
C/EBPβ-dependent epigenetic memory induces trained immunity in hematopoietic stem cells.
de Laval, B., Maurizio, J., Kandalla, P.K., Brisou, G., Simonnet, L., Huber, C., Gimenez, G., Matcovitch-Natan, O., Reinhardt, S., David, E., Mildner, A., Leutz, A., Nadel, B., Bordi, C., Amit, I., Sarrazin, S. and Sieweke, M.H.
Cell Stem Cell 26
(5): 657-674.
May 2020
SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency.
de Melo Costa, V.R., Pfeuffer, J., Louloupi, A., Ørom, U.A.V. and Piro, R.M.
BMC Bioinformatics 22
(1): 368.
15 July 2021
SMOG 2 and OpenSMOG: extending the limits of structure-based models.
de Oliveira, A.B., Contessoto, V.G., Hassan, A., Byju, S., Wang, A., Wang, Y., Dodero-Rojas, E., Mohanty, U., Noel, J.K., Onuchic, J.N. and Whitford, P.C.
Protein Science 31
(1): 158-172.
January 2022
A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P., Kaergel, E., Heinig, M., Fontaine, J.F., Patone, G., Muro, E.M., Mathas, S., Hummel, M., Andrade-Navarro, M.A., Hübner, N. and Scheidereit, C.
Genome Medicine 8
(1): 28.
17 March 2016
Pandemieforschung: von Autoantikörpern und Impfstoff-Innovationen.
de la Rosa, K.
BIOspektrum 29
(6): 614-616.
October 2023
Determination of alpha-1 acid glycoprotein in patients with Ph+ chronic myeloid leukemia during the first 13 weeks of therapy with STI571.
le Coutre, P., Kreuzer, K.A., Na, I.K., Lupberger, J., Holdhoff, M., Appelt, C., Schwarz, M., Mueller, C., Gambacorti-Passerini, C., Platzbecker, U., Bonnet, R., Ehninger, G. and Schmidt, C.A.
Blood Cells Molecules and Diseases 28
(1): 75-85.
January 2002
Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogeneic stem cell transplantation.
le Coutre, P., Meisel, H., Hofmann, J., Roecken, C., Vuong, G.L., Neuburger, S., Hemmati, P.G., Doerken, B. and Arnold, R.
Gut 58
(5): 699-702.
May 2009
BCR-ABL positive cells and chronic myeloid leukemia in immune suppressed organ transplant recipients.
le Coutre, P., Reinke, P., Neuhaus, R., Trappe, R., Ringel, F., Lalancette, M., Hemmati, P.G., Doerken, B. and Daniel, P.T.
European Journal of Haematology 84
(1): 26-33.
1 January 2010
Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.
van Dongen, J.J., Seriu, T., Panzer-Gruemayer, E.R., Biondi, A., Pongers-Willemse, M.J., Corral, L., Stolz, F., Schrappe, M., Masera, G., Kamps, W.A., Gadner, H., van Wering, E.R., Ludwig, W.D., Basso, G., de Bruijn, M.A., Cazzaniga, G., Hettinger, K., van der Does-van den Berg, A., Hop, W.C., Riehm, H. and Bartram, C.R.
Lancet 352
(9142): 1731-1738.
28 November 1998
The translational landscape of the human heart.
van Heesch, S., Witte, F., Schneider-Lunitz, V., Schulz, J.F., Adami, E., Faber, A., Kirchner, M., Maatz, H., Blachut, S., Sandmann, C.L., Kanda, M., Worth, C.L., Schafer, S., Calviello, L., Merriott, R., Patone, G., Hummel, O., Wyler, E., Obermayer, B., Mücke, M., Lindberg, E.L., Trnka, F., Memczak, S., Schilling, M., Felkin, L.E., Barton, P.J.R., Quaife, N.M., Vanezis, K., Diecke, S., Mukai, M., Mah, N., Oh, S.J., Kurtz, A., Schramm, C., Schwinge, D., Sebode, M., Harakalova, M., Asselbergs, F.W., Vink, A., de Weger, R.A., Viswanathan, S., Widjaja, A.A., Gärtner-Rommel, A., Milting, H., Dos Remedios, C., Knosalla, C., Mertins, P., Landthaler, M., Vingron, M., Linke, W.A., Seidman, J.G., Seidman, C.E., Rajewsky, N., Ohler, U., Cook, S.A. and Hubner, N.
Cell 178
(1): 242-260.
27 June 2019
The genomic and spatial mobility of extrachromosomal DNA and its implications for cancer therapy.
van Leen, E., Brückner, L. and Henssen, A.G.
Nature Genetics 54
(2): 107-114.
February 2022
Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE.
van Zwam, M., Huizinga, R., Melief, M.J., Wierenga-Wolf, A.F., van Meurs, M., Voerman, J.S., Biber, K.P., Boddeke, H.W., Höpken, U.E., Meisel, C., Meisel, A., Bechmann, I., Hintzen, R.Q., 't Hart, B.A., Amor, S., Laman, J.D. and Boven, L.A.
Journal of Molecular Medicine 87
(3): 273-286.
March 2009
Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation.
van de Pavert, S.A., Olivier, B.J., Goverse, G., Vondenhoff, M.F., Greuter, M., Beke, P., Kusser, K., Höpken, U.E., Lipp, M., Niederreither, K., Blomhoff, R., Sitnik, K., Agace, W.W., Randall, T.D., de Jonge, W.J. and Mebius, R.E.
Nature Immunology 10
(11): 1193-1199.
November 2009
Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.
van den Akker, E., van Dijk, T., Parren-van Amelsvoort, M., Grossmann, K.S., Schaeper, U., Toney-Earley, K., Waltz, S.E., Loewenberg, B. and von Lindern, M.
Blood 103
(12): 4457-4465.
1 January 2004
USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells.
van den Berk, P., Lancini, C., Company, C., Serresi, M., Sanchez-Bailon, M.P., Hulsman, D., Pritchard, C., Song, J.Y., Schmitt, M.J., Tanger, E., Popp, O., Mertins, P., Huijbers, I.J., Jacobs, H., van Lohuizen, M., Gargiulo, G. and Citterio, E.
Cell Reports 33
(13): 108533.
29 December 2020
The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation.
von Delbrück, M., Kniss, A., Rogov, V.V., Pluska, L., Bagola, K., Löhr, F., Güntert, P., Sommer, T. and Dötsch, V.
Molecular Cell 62
(6): 918-928.
16 June 2016
SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations.
von Eichborn, J., Dunkel, M., Gohlke, B.O., Preissner, S.C., Hoffmann, M.F., Bauer, J.M.J., Armstrong, J.D., Schaefer, M.H., Andrade-Navarro, M.A., Le Novere, N., Croning, M.D.R., Grant, S.G.N., van Nierop, P., Smit, A.B. and Preissner, R.
Nucleic Acids Research 41
(D1): D834-D840.
1 January 2013
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
von Eyss, B., Maaskola, J., Memczak, S., Möllmann, K., Schuetz, A., Loddenkemper, C., Tanh, M.D., Otto, A., Muegge, K., Heinemann, U., Rajewsky, N. and Ziebold, U.
EMBO Journal 31
(4): 972-985.
15 February 2012
Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway.
von Haefen, C., Gillissen, B., Hemmati, P.G., Wendt, J., Guener, D., Mrozek, A., Belka, C., Doerken, B. and Daniel, P.T.
Oncogene 23
(50): 8320-8332.
27 September 2004
Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway.
von Haefen, C., Wendt, J., Semini, G., Sifringer, M., Belka, C., Radetzki, S., Reutter, W., Daniel, P.T. and Danker, K.
Apoptosis 16
(6): 636-651.
March 2011
Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.
von Haefen, C., Wieder, T., Essmann, F., Schulze-Osthoff, K., Doerken, B. and Daniel, P.T.
Oncogene 22
(15): 2236-2247.
1 April 2003
Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.
von Haefen, C., Wieder, T., Gillissen, B., Staerck, L., Graupner, V., Doerken, B. and Daniel, P.T.
Oncogene 21
(25): 4009-4019.
6 June 2002
Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V., McShane, E., Schulz-Beiss, K.W., Patone, G., Schleussner, N., Kolesnichenko, M., Hübner, N., Daumke, O., Selbach, M., Akalin, A., Mathas, S. and Scheidereit, C.
Blood 133
(13): 1489-1494.
28 March 2019
High-affinity T-cell receptor specific for MyD88 L265P mutation for adoptive T-cell therapy of B-cell malignancies.
Çınar, Ö., Brzezicha, B., Grunert, C., Kloetzel, P.M., Beier, C., Peuker, C.A., Keller, U., Pezzutto, A. and Busse, A.
Journal for ImmunoTherapy of Cancer 9
(7): e002410.
30 July 2021
Long-term impact of scheduled regular endoscopic interventions for patients with primary sclerosing cholangitis.
Özdirik, B., Veltzke-Schlieker, W., Nicklaus, J.M., Berger, H., Schmidt, D., Leonhardt, S., Penndorf, V., Adler, A., Müller, T., Wree, A., Tacke, F. and Sigal, M.
Hepatology Communications 8
(9): e0494.
September 2024
Soluble urokinase plasminogen activator receptor levels are associated with severity of fibrosis in patients with primary sclerosing cholangitis.
Özdirik, B., Maibier, M., Scherf, M., Nicklaus, J.M., Frohme, J., Puengel, T., Meyer Zum Büschenfelde, D., Tacke, F., Mueller, T. and Sigal, M.
Journal of Clinical Medicine 11
(9): 2479.
28 April 2022
Biliary microbial patterns in primary sclerosing cholangitis are linked to poorer transplant-free survival.
Özdirik, B., Scherf, M., Brumercek, A., Nicklaus, J.M., Kruis, T., Haber, P.K., Pratschke, J., Tacke, F. and Sigal, M.
Hepatology Communications 7
(6): e0156.
June 2023
Book Section
Leukemia.
Bargou, R. and Ludwig, W.D.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 1.
Springer, Berlin [u.a.], 967-974.
ISBN 3-540-44244-8
2006
Die Buergerkonferenz zur Stammzellforschung.
Ben Salem, A. and Tannert, C.
In:
Stammzellen im Diskurs.
oekom, Muenchen, 106-116.
ISBN 3-928244-69-X
1 January 2004
Information flow in a mammalian signal transduction pathway.
Benary, M., Nolis, I., Blüthgen, N. and Loewer, A.
In:
Information- and Communication Theory in Molecular Biology.
Lecture Notes in Bioengineering
.
Springer, Cham, Switzerland, 101-114.
ISBN 978-3-319-54728-2
2018
Erfahrungen mit der Hyperthermen Radiochemotherapie (HRCT) beim Plattenepithelkarzinom des Oesophagus: Ergebnisse einer prospektiven Studie.
Benhidjeb, T., Huenerbein, M., Koswig, S., Moesta, T., Budach, V. and Schlag, P.M.
In:
Digitale Revolution in der Chirurgie : 119. Kongress der Deutschen Gesellschaft fuer Chirurgie, 7. - 10. Mai 2002, Berlin.
Springer, Berlin [u.a.], 344-344.
ISBN 978-3-540-44330-8
2002
The role of inflammation for tumour growth and tumour suppression.
Blankenstein, T.
In:
Cancer and inflammation : Symposium on Cancer and Inflammation, held at the Novartis Foundation, London, 12-14 November 2002.
Novartis Foundation Symposium ; 256
.
Wiley, Hoboken, N.J., 205-210.
ISBN 0-470-85510-X
23 January 2004
Cell division.
Boden, C. and Ziebold, U.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 1.
Springer, Berlin [u.a.], 233-236.
ISBN 3-540-44244-8
2006
Zellzyklus und Apoptose.
Daniel, P.T.
In:
Molekularmedizinische Grundlagen von haematologischen Neoplasien.
Molekulare Medizin
.
Springer, Berlin [u.a.], 130-184.
ISBN 3-540-41640-4
1 January 2003
Public participation in technology evaluation and risk communication.
Elvers, H.D. and Tannert, C.
In:
Electromagnetic Field Exposure: Risk Communication in the context of Uncertainty.
UNSPECIFIED, 265-274.
2009
Proteasomal degradation of misfolded proteins.
Gauss, R., Neuber, O. and Sommer, T.
In:
Chaperones.
Topics in Current Genetics ; 16
.
Springer, Berlin [u.a.], 185-220.
ISBN 3-540-32580-8
2006
AIDS-Erreger aus dem Militaerlabor - Ignoranz oder bewusste Desinformation?
Geissler, E.
In:
Natur und Kultur. Biologie im Spannungsfeld von Naturphilosophie und Darwinismus.
VWB Verlag fuer Wissenschaft und Bildung, Berlin, 489-508.
ISBN 978-3-86135-393-5
2009
Biologische Waffen: Bedrohung, Hysterie und Psychoterror.
Geissler, E.
In:
Hubertusburger Frieden - ewiger Frieden?! : Protokollband / 1. Hubertusburger Friedensgespraeche, 21. - 23. September 2006, Schloss Hubertusburg, Wermsdorf.
Turnshare, London, 217-230.
ISBN 978-1-903343-99-9
2007
Applications of high-throughput sequencing.
Goya, R., Meyer, I.M. and Marra, M.A.
In:
Bioinformatics for High Throughput Sequencing.
Springer, 27-53.
ISBN 978-1-4614-0781-2
22 September 2011
Telepresence over satellite.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In:
Cars 2003: Computer assisted radiology and surgery, proceedings.
International congress series ; 1256, 1256
.
Elsevier, Amsterdam, 273-278.
ISBN 0531-5131
June 2003
Telemedical applications and Grid technology.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Kaiser, S. and Albayrak, S.
In:
Network Architectures, Management, and Applications III.
Proceedings of SPIE ; 6022
.
SPIE, Bellingham, Wash., 60220F (Article Number).
ISBN 0-8194-6053-2
5 December 2005
Sentinel-Lymphknoten-Biopsie beim Magenkarzinom.
Gretschel, S. and Schlag, P.M.
In:
Sentinel Lymphknoten Biopsie.
ecomed, Landsberg, 175-190.
ISBN 3-609-16009-8
1 January 2001
Essentials of miRNA-dependent control of mRNA translation and decay, miRNA targeting principles, and methods for target identification.
Grosswendt, S. and Rajewsky, N.
In:
Essentials of noncoding RNA in neuroscience: ontogenetics, plasticity of the vertebrate brain.
Academic Press, London, 19-38.
ISBN 978-012804402-5
2017
B cell localization and migration in health and disease.
Hauser, A.E. and Höpken, U.E.
In:
Molecular Biology of B Cells.
Academic Press, 187-214.
ISBN 978-0-12-397933-9
2015
Structural genomics: structure-to-function approaches.
Heinemann, U.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1810-1816.
ISBN 3-540-44244-8
2006
Transcriptome-wide identification of protein binding sites on RNA by PAR-CLIP (photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation).
Hoell, J.I., Hafner, M., Landthaler, M., Ascano, M., Farazi, T.A., Wardle, G., Nusbaum, J., Cekan, P., Khorshid, M., Burger, L., Zavolan, M. and Tuschl, T.
In:
Handbook of RNA Biochemistry: Second, Completely Revised and Enlarged Edition.
Wiley-VCH, Weinheim, 877-898.
ISBN 9783527327645
2014
Ductoscopy of intraductal neoplasia of the breast.
Huenerbein, M., Raubach, M., Dai, K. and Schlag, P.M.
In:
Minimally Invasive Breast Biopsies.
Recent Results in Cancer Research, 173
.
Springer, Berlin, 129-136.
ISBN 978-3-540-31403-5
2009
The interdisciplinary science of T-cell recognition.
Huppa, J.B. and Davis, M.M.
In:
Advances in Immunology.
Advances in Immunology, 119
.
Elsevier, 1-50.
ISBN 978-0-12-407707-2
22 July 2013
Mechanistic insights into T-Cell antigen recognition through single molecule microscopy.
Huppa, J.B. and Schütz, G.J.
In:
Encyclopedia of Cell Biology.
Encyclopedia of Cell Biology, 5
.
Elsevier, 536-552.
ISBN 978-0-12-821624-8
2023
Single molecule methods to measure receptor–ligand interaction in immunological synapses.
Huppa, J.B. and Schütz, G.J.
In:
Encyclopedia of Cell Biology.
Reference Module in Biomedical Sciences, 3
.
Elsevier, 660-666.
ISBN 978-0-12-394796-3
2016
Microbiome and diseases: colorectal cancer.
Iftekhar, A., Sperlich, A., Janssen, K.P. and Sigal, M.
In:
The Gut Microbiome in Health and Disease.
Springer, Cham, 231-249.
ISBN 978-3-319-90544-0
2018
Transposons.
Ivics, Z., Walisko, O. and Izsvak, Z.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1915-1919.
ISBN 3-540-44244-8
2006
Molecular imaging of breast cancer in a transgene mouse model [Molekulare Bildgebung des Mammakarzinoms in einem transgenen Mausmodell].
Jakob, J., Perlitz, C., Ebert, B., Klamm, U., Kemmner, W., Haensch, W., Macdonald, R., Licha, K., Schirner, M., Schlag, P.M. and Moesta, K.T.
In:
Chirurgisches Forum 2005 : fuer experimentelle und klinische Forschung 122. Kongress der Deutschen Gesellschaft fuer Chirurgie Berlin, 05.04.-08.04.2005.
Deutsche Gesellschaft fuer Chirurgie, 34
.
Springer, Berlin, 83-85.
2005
Models of cancer development: Genetic and environmental influences.
Jandrig, B.
In:
Cancer Risk Evaluation: Methods and Trends.
Wiley-VCH, Weinheim, Germany, 9-24.
ISBN 9783527327539
20 April 2011
The 2008 stem cell research debate in Germany.
Jandrig, B.
In:
AICGS German-American Issues.
American Institute for Contemporary German Studies, 37-42.
ISBN 1-933942-15-0
2008
Identification and analysis of pre-symptomatic tumor diagnostics.
Jandrig, B.
In:
Methods, possibilities and perspectives of pre-symptomatic tumor diagnostics.
Pre-symptomatic tumor diagnostics
(1).
Pabst Science Publishers, Lengerich, 237-248.
ISBN 3-89967-254-2
2005
Die Bedeutung molekulargenetischer Veraenderungen fuer eine verbesserte Frueherkennung und Risikoabschaetzung beim Brustkrebs.
Jandrig, B. and Scherneck, S.
In:
Onkologie : Grundlagen - Diagnostik - Therapie - Entwicklungen.
ecomed Medizin, 1-32.
ISBN 978-3-609-76300-2
2010
Genetische Alterationen und tumorassoziierte Gene.
Jandrig, B. and Scherneck, S.
In:
Molekulare Medizin in der Frauenheilkunde : Diagnostik und Therapie.
Steinkopff, Darmstadt, 21-30.
ISBN 3-7985-1301-5
2002
Leakage in cytochrome P450 reactions in relation to protein structural properties.
Jung, C.
In:
Metal Ions in Life Sciences: The Ubiquitous Roles of Cytochrome P450 Proteins.
John Wiley & Sons, 187-234.
ISBN 9780470016725
23 March 2007
Von der Haemkatalyse zum Cytochrom P450.
Jung, C.
In:
Zwischen Wissenschaft und Politik : Festkolloquium zum 80. Geburtstag von Werner Scheler ; [19.09.2003 in Berlin].
Sitzungsberichte der Leibniz-Sozietaet ; 67/2004
.
trafo Verl., Berlin, 49-68.
ISBN 3-89626-493-1
1 January 2004
High pressure as tool to study structural properties of thiolate heme proteins.
Jung, C., Canny, B. and Chervin, J.C.
In:
Advances in High-Pressure Biosciences and Biotechnology.
Springer, Heidelberg, 19-24.
ISBN 978-3-642-05674-1
2003
Heme pocket compressibility in P450cam-CO high pressure effect on the FTIR CO stretch mode.
Jung, C., Canny, B., Chervin, J.C. and Hoa, G.H.B.
In:
Cytochromes P450, Biochemistry, Biophysics and Drug Metabolism. 13th International Conference on Cytochromes P450. Prague, June 29 - July 3, 2003.
Monduzzi Editore, Prague, 195-199.
ISBN 88-323-3142
1 January 2003
Intermediate radical formation by the iron-oxo complex produced in the reaction of cytochrome P450 with oxidants.
Jung, C., Schuenemann, V., Lendzian, F., Contzen, J., Barra, A.L. and Trautwein, A.X.
In:
Cytochromes P450, Biochemistry, Biophysics and Drug Metabolism. 13th International Conference on Cytochromes P450, Prague, June 29 - July 3, 2003.
Monduzzi Editore, Prague, 201-205.
ISBN 88-323-3141-1
1 January 2003
Abklärung und OP-Indikationen bei malignen Lymphknoten des unteren GI-Traktes.
Keller, U. and Merz, I.
In:
Chirurgie des unteren Gastrointestinaltrakts und Allgemeine Chirurgie.
Springer Reference Medizin
.
Springer, Berlin, Heidelberg, 177-185.
ISBN 978-3-662-63355-7
31 July 2024
Transcriptomics and cancer risk assessment.
Kemmner, W.
In:
Cancer risk evaluation : methods and trends.
Wiley-VCH, Weinheim, 195-205.
ISBN 9783527327539
27 April 2011
Systems biology approach to study cancer metabolism.
Kempa, S. and Royla, N.
In:
Encyclopedia of Cancer.
Elsevier / Academic Press, 426-428.
ISBN 978-0-12-812485-7
2019
Die Sentinel-Node-Biopsie beim malignen Melanom.
Kettelhack, C. and Schlag, P.M.
In:
Sentinel Lymphknoten Biopsie.
ecomed, Landsberg, 87-100.
ISBN 3-609-16009-8
1 January 2001
Minicircle-based vectors for nonviral gene therapy: in vitro characterization and in vivo application.
Kobelt, D., Aumann, J., Schleef, M., Schmeer, M., Stein, U., Schlag, P.M. and Walther, W.
In:
Minicircle and miniplasmid DNA vectors: the future of nonviral and viral gene transfer.
Wiley, 177-188.
ISBN 978-3-527-32456-9
17 April 2013
Resolution in electron tomography.
Kudryashev, M.
In:
Cellular Imaging.
Biological and Medical Physics, Biomedical Engineering
.
Springer, Cham, Switzerland, 261–282.
ISBN 978-3-319-68995-1
31 December 2017
Mouse models in cancer research.
Lee, S. and Schmitt, C.A.
In:
Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts.
UNSPECIFIED, 671-701.
ISBN 9783527312375
6 February 2006
Mammachirurgie.
Liebeskind, U. and Schlag, P.M.
In:
Jahrbuch der Chirurgie.
Biermann, Koeln, 175-196.
ISBN 3-930-50542-8
1 January 2003
Konzept und Entwicklung des Lymphatic Mapping und der Sentinel-Node-Biopsie.
Liebeskind, U. and Schlag, P.M.
In:
Sentinel Lymphknoten Biopsie.
ecomed, Landsberg, 11-18.
ISBN 3-609-16009-8
1 January 2001
Chemokine-controlled migration in lymphoid organogenesis and the systemic organization of immunity.
Lipp, M.
In:
Cell Migration in Development and Disease.
Wiley-VCH, Weinheim, 251-273.
ISBN 3-527-30587-4
1 January 2005
Antimetaboliten.
Matthes, E. and Langen, P.
In:
Grundlagen der Molekularen Medizin.
Molekulare Medizin
.
Springer, Berlin [u.a.], 631-679.
ISBN 3-540-43207-8
1 January 2003
Tumorantigene und ihre Nutzung fuer eine Therapie mit Antikoerpern.
Micheel, B.
In:
Tumorerkrankungen.
Handbuch der Molekularen Medizin ; 2
.
Springer, Berlin [u.a.], 160-185.
ISBN 3-540-62463-5
1 January 1998
Myb partnerships.
Mo, X., Kowenz-Leutz, E. and Leutz, A.
In:
Myb Transcription Factors: Their Role in Growth, Differentiation and Disease.
Proteins and Cell Regulation
.
Kluwer, Dordrecht, 239-256.
ISBN 978-1-4020-2779-6
1 January 2004
Fluorimetrische Methoden in der chirurgischen Diagnostik.
Moesta, K.T., Ebert, B., Handke, T., Rinneberg, H. and Schlag, P.M.
In:
Klinische Fluoreszenzdiagnostik und Photodynamische Therapie.
Blackwell, Berlin [u.a.], 82-93.
ISBN 3-89412-510-1
1 January 2003
MACC1, a novel player in solid cancer carcinogenesis.
Mudduluru, G., Ilm, K., Dahlmann, M. and Stein, U.
In:
Mechanisms of Molecular Carcinogenesis - Volume 1.
Springer, Cham, 11-38.
ISBN 978-3-319-53657-6
2017
MAD phasing.
Mueller, J.J. and Heinemann, U.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1002-1008.
ISBN 3-540-44244-8
2006
Roles of microRNAs in B lymphocyte physiology and oncogenesis.
Muljo, S.A. and Rajewsky, K.
In:
Molecular Biology of B Cells.
Academic Press, 65-73.
ISBN 978-0-12-397933-9
2015
Molekuelmodelle und Modellmolekuele: Strukturanalyse grosser biologischer Molekuele fuer die Medizin.
Muller, Y.A. and Heinemann, U.
In:
Grundlagen der Molekularen Medizin.
Molekulare Medizin
.
Springer, Berlin [u.a.], 340-359.
ISBN 3-540-43207-8
1 January 2003
Molekuelmodelle und Modellmolekuele: Strukturanalyse grosser biologischer Molekuele fuer die Medizin.
Muller, Y.A. and Heinemann, U.
In:
Handbuch der molekularen Medizin, Band 1, Molekular- und zellbiologische Grundlagen.
Springer, Berlin [u.a.], 340-359.
ISBN 978-3-662-07589-0
2003
Natural antisense transcripts within pseudogenes: an EST survey.
Muro, E.M. and Andrade-Navarro, M.A.
In:
Non-coding RNAs and epigenetic regulation of gene expression : drivers of natural selection.
Caister Academic Press, Norfolk, 99-108.
ISBN 978-1-904455-94-3
February 2012
Integration von Buergerbeteiligung als politische Aufgabe?
Niewoehner, J.
In:
Stammzellen im Diskurs.
oekom, Muenchen, 67-74.
ISBN 3-928244-69-X
1 January 2004
Genomic landscape and clonal evolution of AML.
Noerenberg, D., Damm, F. and Bullinger, L.
In:
Acute Myeloid Leukemia.
Hematologic Malignancies
.
Springer, Cham, 103-118.
ISBN 978-3-030-72675-1
2021
Nuclear import and export.
Pannek, A. and Stade, K.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1320-1324.
ISBN 3-540-44244-8
2006
Stand der Stammzelldebatte in Deutschland : Stand der Stammzellforschung.
Pompe, S. and Tannert, C.
In:
Stammzellen im Diskurs.
oekom, Muenchen, 92-105.
ISBN 3-928244-69-X
1 January 2004
Maligne Tumoren des Gastrointestinaltraktes.
Reichardt, P. and Schlag, P.M.
In:
Harrisons Innere Medizin.
ABW Wiss.-Verl., Berlin, 639-648.
ISBN 3-936072-10-8
1 January 2003
Apoptosis and cancer therapy.
Reimann, M. and Schmitt, C.A.
In:
Apoptosis, Cell Signaling, and Human Diseases.
Humana Press, 303-320.
ISBN 978-1-58829-677-1
2007
Paired sage-microarray expression data sets reveal antisense transcripts differentially expressed in embryonic stem cell differentiation.
Sandie, R., Porter, C.J., Palidwor, G.A., Price, F., Krzyzanowski, P.M., Muro, E.M., Hoersch, S., Smith, M., Campbell, P.A., Perez-Iratxeta, C., Rudnicki, M.A. and Andrade-Navarro, M.A.
In:
Computational Biology of Embryonic Stem Cells.
Bentham, Oak Park, 193-215.
ISBN 978-1-608-05025-3
2012
The human transcriptome: implications for the understanding of human disease.
Schaefer, R., Kemmner, W. and Sers, C.
In:
Molecular pathology: the molecular basis of human disease.
Elsevier, Academic Press, Amsterdam, 123-149.
ISBN 978-0-12-374419-7
2009
HGF/SF c-Met signaling in the epithelial-mesenchymal transition and migration of muscle progenitor cells.
Schaeper, U. and Birchmeier, W.
In:
Cell Migration in Development and Disease.
Wiley-VCH, Weinheim, 191-204.
ISBN 3-527-30587-4
1 January 2005
Tyrosine kinases.
Schaeper, U. and Grossmann, K.S.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1951-1959.
ISBN 3-540-44244-8
2006
NF-κB pathway.
Scheidereit, C. and Krappmann, D.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1286-1292.
ISBN 3-540-44244-8
2006
Bedeutung molekulargenetischer Veränderungen für eine verbesserte Risikoabschätzung beim Brustkrebs.
Scherneck, S. and Jandrig, B.
In:
Handbuch Onkologie : Grundlagen, Diagnostik, Therapie, Entwicklungen.
ecomed, Landsberg/Lech, 1-21.
ISBN 3-609-76300-0
December 1997
Die kulturelle Vielfalt in der Bioethik-Debatte.
Schicktanz, S.
In:
Kulturelle Aspekte der Biomedizin: Bioethik, Religionen und Alltagsperspektiven.
Campus-Verl., Frankfurt am Main, 263-282.
ISBN 3-593-37388-2
1 January 2003
Maligne Tumoren des Duenndarms.
Schlag, P.M. and Benhidjeb, T.
In:
Chirurgische Onkologie.
Thieme, Stuttgart [u.a.], 389-398.
ISBN 3-13-126111-0
1 January 2002
Maligne Hauttumoren.
Schlag, P.M. and Kettelhack, C.
In:
Chirurgische Onkologie.
Thieme, Stuttgart [u.a.], 494-521.
ISBN 3-13-126111-0
1 January 2002
Weichgewebssarkome.
Schlag, P.M. and Kettelhack, C.
In:
Chirurgische Onkologie.
Thieme, Stuttgart [u.a.], 521-545.
ISBN 3-13-126111-0
1 January 2002
Tumorschmerztherapie.
Schlag, P.M., Kumpf, O. and Papstein, V.
In:
Chirurgische Onkologie.
Thieme, Stuttgart [u.a.], 52-79.
ISBN 3-13-126111-0
1 January 2002
Tumoren der Brustdruese.
Schlag, P.M., Liebeskind, U. and Bembenek, A.
In:
Chirurgische Onkologie.
Thieme, Stuttgart [u.a.], 96-141.
ISBN 3-13-126111-0
1 January 2002
Knochentumoren.
Schlag, P.M., Schmidt-Peter, P. and Tunn, P.U.
In:
Chirurgische Onkologie.
Thieme, Stuttgart [u.a.], 546-569.
ISBN 3-13-126111-0
1 January 2002
Metastasen bei unbekanntem Primaertumor.
Schlag, P.M. and Reichardt, P.
In:
Harrisons Innere Medizin.
ABW Wiss.-Verl., Berlin, 697-705.
ISBN 3-936072-10-8
1 January 2003
Sarkome der Weichteile und des Knochens.
Schlag, P.M. and Reichardt, P.
In:
Harrisons Innere Medizin.
ABW Wiss.-Verl., Berlin, 692-696.
ISBN 3-936072-10-8
1 January 2003
Hochmaligne B-Zell-Lymphome.
Schlegelberger, B. and Lipp, M.
In:
Molekularmedizinische Grundlagen von haematologischen Neoplasien.
Molekulare Medizin
.
Springer, Berlin [u.a.], 456-478.
ISBN 3-540-41640-4
1 January 2003
Measurement of forces acting on single T-cell receptors.
Schrangl, L., Göhring, J., Kellner, F., Huppa, J.B. and Schütz, G.J.
In:
Imaging cell signaling.
Methods in Molecular Biology, 2800
.
Humana New York, NY, New York, NY, USA, 147-165.
ISBN 978-1-0716-3834-7
7 May 2024
ANCA-associated vasculitis and the mechanisms of tissue injury.
Schreiber, A. and Choi, M.
In:
Systemic Vasculitides: Current Status and Perspectives.
Springer, Cham, 141-158.
ISBN 978-3-319-40134-8
14 October 2016
Förster resonance energy transfer to study TCR-pMHC interactions in the immunological synapse.
Schütz, G.J. and Huppa, J.B.
In:
The immune synapse.
Methods in Molecular Biology, 1584
.
Springer Nature, New York, NY, USA, 207-229.
ISBN 978-1-4939-8327-8
3 March 2017
Darbepoetin-α verringert die Nekroinflammation und mildert die cholestatische Fibrose in Mäusen [Darbepoetin-alpha inhibits the perpetuation of necro-inflammation and attenuates cholestatic fibrosis in mice].
Sigal, M., Siebert, N., Abshagen, K., Vollmar, B. and Eipel, C.
In:
Chirurgisches Forum und DGAV Forum 2010.
Deutsche Gesellschaft für Chirurgie, 39
.
Springer, Berlin, Heidelberg, 203-205.
ISBN 978-3-642-12191-3
2010
Ubiquitination.
Sommer, T. and Dittmar, G.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1964-1968.
ISBN 3-540-44244-8
2006
Limb development.
Soshnikova, N. and Birchmeier, W.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 1.
Springer, Berlin [u.a.], 976-981.
ISBN 3-540-44244-8
2006
Deciphering the universe of RNA structures and trans RNA-RNA interactions of transcriptomes in vivo: from experimental protocols to computational analyses.
Stefanov, S.R. and Meyer, I.M.
In:
Systems Biology.
RNA Technologies
.
Springer, Cham, 173-216.
ISBN 978-3-319-92966-8
2018
Multidrug resistance.
Stein, U.
In:
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2.
Springer, Berlin [u.a.], 1208-1212.
ISBN 3-540-44244-8
2006
Die Szenario-Technik. Das Verfahren im Ueberblick.
Tannert, C.
In:
Konfliktfelder beackern.
Ethik interdisziplinaer, 11
.
Lit, Berlin, 97-106.
ISBN 978-3-8258-9320-0
2009
Handlungsfaehig im Dilemma.
Tannert, C.
In:
Politisches Denken ist : Festschrift fuer Margot von Renesse.
Lang, Frankfurt am Main, 165-168.
ISBN 3-631-53977-0
1 January 2005
Biomedizin als Gegenstand des interkulturellen Diskurses.
Tannert, C.
In:
Kulturelle Aspekte der Bioethik und Biomedizin.
Campus-Verl., Frankfurt/M., 7-15.
1 January 2003
Stammzellen koennen unser Leben veraendern.
Tannert, C. and Wiedemann, P.
In:
Stammzellen im Diskurs.
oekom, Muenchen, 9-12.
ISBN 3-928244-69-X
1 January 2004
Weichteiltumoren.
Tunn, P.U. and Schlag, P.M.
In:
Lexikon orthopaedische Chirurgie : Standardterminologie fuer Orthopaeden und Unfallchirurgen.
Springer, Berlin [u.a.], 231-233.
ISBN 3-540-41317-0
1 January 2003
Combination suicide gene therapy.
Uckert, W., Salmons, B., Beltinger, C., Guenzburg, W.H. and Kammertoens, T.
In:
Suicide Gene Therapy : Methods and Reviews.
Methods in Molecular Medicine ; 90
.
Humana Press, Totowa, NJ, 345-352.
ISBN 0-89603-971-4
1 January 2004
Needleless jet injection of naked DNA for nonviral in vivo gene transfer.
Walther, W. and Stein, U.
In:
DNA-Pharmaceuticals: Formulation and Delivery in Gene Therapy, DNA Vaccination and Immunotherapy.
Wiley-VCH, 133-143.
ISBN 9783527311873
25 August 2005
Die Risikoabwaegung in der Debatte zur Biomedizin.
Wiedemann, P.
In:
Kulturelle Aspekte der Biomedizin: Bioethik, Religionen und Alltagsperspektiven.
Campus-Verl., Frankfurt am Main, 244-262.
ISBN 3-593-37388-2
1 January 2003
Metabolic and signaling networks.
Wolf, J. and Kempa, S.
In:
Encyclopedia of Systems Biology.
Springer, New York, NY, 1228-1229.
ISBN 978-1-4419-9862-0
5 June 2013
Peyton Rous: a centennial tribute to the founding father of cancer virology.
Wunderlich, V. and Kunze, P.
In:
Cancer Associated Viruses.
Current Cancer Research
.
Springer Science and Business Media, New York, 1-23.
ISBN 978-1-4419-9999-3
2012
Krebs - von Hippokrates bis zur molekularen Medizin. Einige wichtige Etappen auf einem langen Weg.
Wunderlich, V.
In:
Molekularmedizinische Grundlagen von nicht-hereditaeren Tumorerkrankungen.
Molekulare Medizin
(10).
Springer, Berlin [u.a.], 405-425.
ISBN 3-540-41577-7
2002
Redundant human omentum fat: A leap towards regenerative medicine.
lndumathi, S., Harikrishnan, R. and Dhanasekaran, M.
In:
Regenerative Medicine.
Springer, 125-133.
ISBN 978-1-4471-6541-5
2014
Subcutaneous adipose tissue-derived stem cells: advancement and applications in regenerative medicine.
lndumathi, S., Mishra, R., Harikrishnan, R. and Dhanasekaran, M.
In:
Regenerative Medicine.
Springer, 91-112.
ISBN 978-1-4471-6541-5
2014
Conference or Workshop Item
Sparse control of force field dynamics.
Bongini, M., Fornasier, M., Fröhlich, F. and Haghverdi, L.
In: 7th International Conference on NETwork Games, COntrol and OPtimization (NetGCoop), 29 - 31 Oct 2014, Trento, Italy.
8 June 2017
On fine stochastic simulations of liposome-encapsulated PUREsystem(TM).
Calviello, L., Lazzerini-Ospri, L. and Marangoni, R.
In: 10th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2015, 22-25 Sept 2015, Bari, Italy.
2016
Praeklinische Validierung fuer das US-gestuetzte Navigationssystem Liver Track.
Eulenstein, S., Jentsch, M. and Schlag, P.M.
In: Annual Meeting on CURAC (Computer- und Roboterassistierte Chirurgie), 15 Nov 2012, Duesseldorf.
2012
Random caustics and intensity fluctuations in weakly disordered media.
Fleischmann, R., Metzger, J. and Geisel, T.
In: Frontiers in Optics 2012/Laser Science XXVIII, 14-18 Oct 2012, Rochester, NY, USA.
2012
Dataset debt in biomedical language modeling.
Fries, J.A., Seelam, N., Altay, G., Weber, L., Kang, M., Datta, D., Su, R., Garda, S., Wang, B., Ott, S., Samwald, M. and Kusa, W.
In: 2022 Challenges and Perspectives in Creating Large Language Models, 27 May 2022, Virtual, Dublin.
May 2022
New medical technologies of the future.
Graschew, G., Rakowsky, S., Roelofs, T.A. and Schlag, P.M.
In: 2013 International Conference on Digital Technologies (DT), 29-31 May 2013, Zilina, Slovakia.
29 May 2013
Design and implementation of satellite-based networks for global deployment of U-Health.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: 2nd Space Applications Symposium, SPACE APPLI 2008, 22-25 April 2008, Toulouse, France.
2008
From e-learning towards u-learning: ICT-enabled ubiquitous learning and training.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: 10th IASTED International Conference on Computers and Advanced Technology in Education, 8-10 Oct 2007, Beijing, China.
2008
Design of networks for real-time tele-education.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: 6th IASTED International Conference on Web-Based Education, WBE 2007, 14-16 Mar 2007, Chamonix, France.
2007
Design of satellite-based networks for u-health - GALENOS, DELTASS, MEDASHIP, EMISPHER.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: 9th International Conference on e-Health Networking, Application and Services, 19-22 June 2007, Taipei, Taiwan.
2007
Linking structural biology with genome research: Beamlines for the Berlin "Protein Structure Factory" initiative.
Illing, G., Saenger, W. and Heinemann, U.
In: Synchrotron Radiation Instrumentation: SRI99: Eleventh US National Conference, 13-15 Oct 1999, Stanford, CA,USA.
26 June 2000
Nanocapsule induced morphology and migration changes in single cell layers quantified with digital holographic microscopy.
Kaiser, M., Pohl, L., Ketelhut, S., Kastl, L., Gorzelanny, C., Götte, M., Schnekenburger, J., Goycoolea, F.M. and Kemper, B.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
4 March 2019
Cseq-simulator: a data simulator for CLIP-Seq experiments.
Kassuhn, W., Ohler, U. and Drewe, P.
In: Pacific Symposium on Biocomputing (PSB) 2016, 4-8 Jan 2016, The Big Island of Hawaii, USA.
January 2016
Quantitative phase imaging-based concepts for the analysis of global morphology changes in confluent cell layers.
Kemper, B., Pohl, L., Kaiser, M., Doepker, E., Schnekenburger, J. and Ketelhut, S.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
4 March 2019
Label-free detection of global morphology changes in confluent cell layers utilizing quantitative phase imaging with digital holographic microscopy.
Kemper, B., Pohl, L., Kaiser, M., Döpker, E., Schnekenburger, J. and Ketelhut, S.
In: European Conferences on Biomedical Optics 2019, 26-27 Jun 2019, Munich, Germany.
22 July 2019
Automatic calibration of 3D ultrasound probes.
Lange, T., Kraft, S., Eulenstein, S., Lamecker, H. and Schlag, P.M.
In: Workshops Bildverarbeitung fur die Medizin: Algorithmen - Systeme - Anwendungen, BVM 2011, 20-22 Mar 2011, Luebeck, Germany.
13 March 2011
Experimental comparison of landmark-based methods for 3D elastic registration of pre- and postoperative liver CT data.
Lange, T., Woerz, S., Rohr, K. and Schlag, P.M.
In: Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, 07 Febr 2009, Lake Buena Vista, Florida, USA.
13 March 2009
Fast alignment of limited angle tomograms by projected cross correlation.
Sanchez, R.M., Mester, R. and Kudryashev, M.
In: 2019 27th European Signal Processing Conference (EUSIPCO), 2-6 Sep 2019, A Coruna, Spain.
18 November 2019
KDD Health Day/DSHealth 2021: Joint KDD 2021 Health Day and 2021 KDD Workshop on Applied Data Science for Healthcare: state of XAI and trustworthiness in health.
Wang, F., Chakraborty, P., Xu, T., Hsueh, P.Y.S., Sun, X., Stiglic, G., Crane, G., Bian, J., Haghverdi, L., Yao, L. and Buettner, F.
In: KDD '21: The 27th ACM SIGKDD Conference on Knowledge Discovery and Data Mining, 14-18 Aug 2021, Virtual Event Singapore.
14 August 2021
Extend, don’t rebuild: Phrasing conditional graph modification as autoregressive sequence labelling.
Weber, L., Münchmeyer, J., Garda, S. and Leser, U.
In: 2021 Conference on Empirical Methods in Natural Language Processing, EMNLP 2021, 7-11 Nov 2021, Punta Cana, Dominican Republic.
November 2021
Book
Gene therapy of cancer : methods and protocols.
Walther, Wolfgang, ed.
Methods in Molecular Biology, 2521
(3).
Springer / Humana Press, New York, NY.
ISBN 9781071624401
2022
Metastasis : methods and protocols.
Stein, U.S., ed.
Methods in Molecular Biology, 2294
.
Springer / Humana Press, New York, NY.
ISBN 978-1-0716-1349-8
2021
Current strategies in cancer gene therapy.
Walther, W., ed.
Recent Results in Cancer Research, 209
.
Springer.
ISBN 978-3-319-42932-8
2016
Metabolism in cancer.
Cramer, T. and Schmitt, C., eds.
Recent Results in Cancer Research, 207
.
Springer.
ISBN 978-3-319-42118-6
2016
Cancer risk evaluation: methods and trends.
Obe, G., Jandrig, B., Marchant, G.E., Schuetz, H. and Wiedemann, P.M., eds.
Wiley-Blackwell, Weinheim.
ISBN 978-3-527-32753-9
2011
Walking Molecular Pathways. 8th MDC/FMP PhD Student Retreat / September 7th - 9th 2006, Hotel Residenz, Motzen.
UNSPECIFIED, ed.
MDC/FMP, Berlin.
September 2006
Biopolitik und Regenerative Medizin - Pro und Contra : Dokumentation eines Internationalen Kongresses 7. bis 8. April 2005 in Berlin.
Franzen, M, Wiedemann, PM and Tannert, C, eds.
Infix, Berlin.
ISBN 3-89838-066-1
1 January 2005
Stammzellen im Diskurs. Ein Lese- und Arbeitsbuch zu einer Buergerkonferenz.
Tannert, C and Wiedemann, P, eds.
oekom Verl., Muenchen.
ISBN 3-936581-69-X
1 January 2004
Monogen bedingte Erbkrankheiten 1.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 6
.
Springer, Berlin [u.a.].
ISBN 3-540-65529-8
1 January 2000
Monogen bedingte Erbkrankheiten 2.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 7
.
Springer, Berlin [u.a.].
ISBN 3-540-65530-1
1 January 2000
TALENs : Methods and Protocols.
Kuehn, R., Wurst, W. and Wefers, B.
Methods in Molecular Biology, 1338
.
Springer, New York.
ISBN 978-1-4939-2931-3
2016
Gene Therapy: Prospective technology assessment in its societal context.
Niewoehner, J. and Tannert, C.
UNSPECIFIED.
ISBN 978-0-444-52806-3
2006
Taschenatlas der Immunologie : Grundlagen - Labor - Klinik.
Pezzutto, A., Ulrichs, T. and Burmester, G.R.
Thieme, Stuttgart [u.a.].
ISBN 3-13-115382-2
1 January 2007
Kulturelle Aspekte der Bioethik und Biomedizin : Bioethik, Religionen und Alltagsperspektiven.
Schicktanz, S., Tannert, C. and Wiedemann, P.
Kultur der Medizin ; 9
.
Campus-Verl., Frankfurt/M..
ISBN 3-593-37388-2
1 January 2003
Thesis
Thermostabilitaet und funktionelle Vielfalt ubiquitaerer Proteinfaltungsdomaenen [Thermostability and functional diversity of ubiquitous protein domains].
Delbrueck, H.
UNSPECIFIED thesis, UNSPECIFIED.
20 September 2002
Mechanismen der Immunmodulation durch die Genprodukte US11 und US28 des humanen Zytomegalievirus.
Droese, J.
UNSPECIFIED thesis, UNSPECIFIED.
8 November 2005
Wissensarbeit und Buergerschaft im Diskurs um die Biomedizin : Ethnografie eines Szenario-Workshops.
Goersdorf, A.
UNSPECIFIED thesis, UNSPECIFIED.
1 January 2003
Deregulation von Zellzyklus und Apoptose beim Plattenepithelkarzinom des Oesophagus.
Guener, D.
UNSPECIFIED thesis, UNSPECIFIED.
30 September 2003
Genetische Analyse von Conductin durch zielgerichtete Mutagenese in der Maus.
Jerchow, B.
UNSPECIFIED thesis, UNSPECIFIED.
6 May 2003
Untersuchungen zur subzellulaeren Lokalisation und zu den Funktionen von YB-1, einem Y-Box-Protein in Saeugerzellen.
Juerchott, K.
UNSPECIFIED thesis, UNSPECIFIED.
23 November 1999
Gene signatures and functional analysis of follicular B helper T cells [Genexpression und funktionelle Analyse von follikulaeren B-Helper T-Zellen].
Rasheed, M.A.U.
UNSPECIFIED thesis, UNSPECIFIED.
12 October 2006
Identifikation molekularer Regulatoren der anti-IgM induzierten B-Zell Apoptose.
Rickers, A.
UNSPECIFIED thesis, UNSPECIFIED.
16 February 1999
Kristallstrukturanalyse des kohlenhydratbindenden Moduls 27-1 der Beta-Mannanase 26 aus Caldicellulosiruptor saccharolyticus im Komplex mit Mannohexaose und Kristallisation der ATPase HP0525 aus Helicobacter pylori.
Roske, Y.
UNSPECIFIED thesis, UNSPECIFIED.
28 July 2005
Tumorspezifische Targeting der humanen natuerlichen Killerzellinie YT durch Gentransfer chimaerer Immunglobulin-T-Zellrezeptoren.
Schirrmann, T.
UNSPECIFIED thesis, UNSPECIFIED.
15 April 2005
Identifikation Apoptose-assoziierter Gene in B-Zellen und Charakterisierung des Genproduktes LAPTM5.
Schneider, H.
UNSPECIFIED thesis, UNSPECIFIED.
16 January 2003
Untersuchungen zur Molekularpathologie des Hodgkin-Lymphoms - Klonierung des I kappa B epsilon Gens und Mutationsanalyse in Einzelzellen.
Theurich, S.
UNSPECIFIED thesis, UNSPECIFIED.
24 July 2006
Untersuchungen zur Regulation des Lipidstoffwechsels in Saccharomyces cerevisiae.
Urban, J.
UNSPECIFIED thesis, UNSPECIFIED.
19 October 2001
Modulierung der NF-kappaB-Aktivitaet in T-Zellen durch den Carmal1-Bcl10-Malt1 Komplex.
Wegener, E.
UNSPECIFIED thesis, UNSPECIFIED.
4 July 2006
Beitraege zur Struktur und Funktion des kleinen Saeuger-Stressproteins HSP25 unter besonderer Beruecksichtigung der Wechselwirkung mit Actin.
Wieske, M.
UNSPECIFIED thesis, UNSPECIFIED.
22 September 1998
Patent
Neues Verfahren zur Durchfuehrung der Positronen-Emissions-Tomographie (PET) mittels 18F-haltigen Nukleosiden.
Baerwolff, D.
DE102005019452A1.
26 October 2006
Fluorinated 3'-deoxythymidine derivatives, a method for their preparation and their use.
Baerwolff, D., Lindner, R., Munz, D.L. and Michael, R.
WO06114336.
2 November 2006
Mittel zur Beeinflussung der Zelldifferenzierung und seine Verwendung.
Birchmeier, W.
DE19509792A1.
19 September 1996
Lebendvakzine gegen Tumorerkrankungen.
Blankenstein, T. and Cayeux-Pezzutto, S.
DE4431401A1.
29 February 1996
Lebendvakzine zur Behandlung von Tumorerkrankungen [Live vaccine for the treatment of tumour diseases].
T. Blankenstein, S. Cayeux.
EP0777499A1 ; EP0777499B1 ; WO9605866A2 ; WO9605866A3 ; US6,039,941.
11 June 1997
Phospho- bzw. Phosphono-(N-acyl)-serine und ihre Herstellung.
Brachwitz, H., Langen, P. and Vollgraf, C.
DE4229877C2.
17 March 1994
Liposomale Zubereitung, ihre Herstellung und ihre Verwendung.
Brandl, M., Bachmann, D., Reszka, R. and Drechsler, M.
DE4430592A1.
22 February 1996
Aenderung des Beladungszustandes von MHC-Molekuelen [Change of the load state of MHC molecules].
Falk, K. and Roetzschke, O.
DE102004054545A1 ; WO0629891.
6 April 2006
Verfahren zur Verbesserung von immuntherapeutischen Verfahren [Method for improving methods of immunotherapy].
Falk, K., Roetzschke, O. and Strominger, J.
WO0316512.
27 February 2003
Verfahren zur Diagnose und Therapie von antioestrogentherapieresistenten Brusttumoren [Diagnosis and therapy of breast tumours resistant to antiestrogen treatment].
Fichtner, I., Becker, M., Besada-Perez, V. and Castellanos-Serra, L.
DE10310198A1 ; WO0408137.
22 January 2004
Verfahren zur Erkennung von Medikamenten gegen Hepatitis C [Method of screening drug for hepatitis C].
Fukushi, S., Kayegama, T., Hoshino, F., Katayama, K., Stahl, J. and Okada, M.
EP1306672A2 ; EP1306672A3.
2 May 2003
Shp-2 inhibitors, pharmaceutical compositions comprising them and their use for treating phosphatase-mediated diseases [Shp-2-Inhibitoren, Arzneimittel, die sie enthalten sowie deren Verwendung zur Behandlung von Phosphatasen-vermittelten Krankheiten].
Hellmuth, K. and Birchmeier, W.
EP1728790 ; WO06128909.
6 December 2006
DNA, kodierend fuer die variable Region eines anti-idiotypischen Antikoerpers.
Karsten, U.
DE59710821D ; EP0937105.
6 November 2003
Gezielte Einfuehrung unnatuerlicher Aminosaeuren in Proteine durch einen modifizierten genetischen Code.
Kurzchalia, T.
DE19500932A1.
18 July 1996
Therapeutics and diagnostics for disorders of erythropoiesis.
Lemke, B., Zenke, M., Hacker, C., Brissette, W.H., Zagouras, P. and Neote, K.S.
WO03038130 ; US2004014064 ; EP1446507.
8 May 2003
Methods and compositions relating to plasmacytoid dendritic cells.
Lipford, G.B., Wagner, H. and Zenke, M.
WO0312061 ; US2003148316.
13 February 2003
2',3'-dideoxynucleoside pyrimidine compounds and carbocyclic analogs.
Matthes, E., Janta-Lipinski, M., Scholz, D., Gaertner, K., Schildt, J., Lehmann, C., Langen, P. and Rosenthal, H.A.
US5,496,935.
5 March 1996
Beta-L-nucleosides and use thereof as pharmaceutical agents for the treatment of viral diseases [Beta-L-Nucleoside und ihre Verwendung als pharmazeutische Mittel zur Behandlung viraler Erkrankungen].
Matthes, E., Janta-Lipinski, M., Will, H., Sirma, H. and Li, L.
EP1668023 ; WO0526186.
24 March 2005
Reconstructed human mariner transposon capable of stable gene transfer into chromosomes in vertebrates [Rekonstruktion eines menschlichen Mariner Transposons, das zum stabilen Gentransfer in Chromosome von Wirbeltieren geeignet ist].
Miskey, C. and Ivics, Z.
EP1710316 ; >WO06108525.
11 October 2006
Integriertes Mikrosystem zur Isolierung von Zellen aus tierischen Geweben.
Pfrieger, F.W.
DE19933016A1.
18 January 2001
Isolierung von Neuronen und Stammzellen fuer Nervenfasern aus einer Probe [Isolation of neurones and stem cells for nerve fibres from a sample].
Pfrieger, F.W. and Naegler, K.
EP1448764 ; WO0342374.
22 May 2003
Anticancer drug with a cytostatic and a contrasting agent.
Reszka, R., Pohlen, U., Stiller, D., Berger, G. and Lippmann, M.
WO9618421 ; US6,479,033.
20 June 1996
Oral verabreichbare pharmazeutische Zubereitung umfassend liposomal verkapseltes Taxol [Orally administered pharmaceutical preparation comprising liposomically encapsulated paclitaxel].
Reszka, R. and Fichtner, I.
DE10154464A1 ; DE10154464B4 ; EP1443904 ; WO0339437.
22 May 2003
Process for treating tumors with cytotoxic substances.
Stein, U., Walther, W. and Schlag, P.M.
US6,582,690.
24 June 2003
Construction of a T cell line-based packaging cell line for the production of T cell receptor retroviruses by enriching of Cd3 expressing cells.
Uckert, W. and Blankenstein, T.
WO0700318.
4 January 2007
TR4, TR4 activators, TR4 inhibitors or TR4-associated molecules for treating leukaemic diseases [TR4, TR4-Aktivatoren, TR4-Inhibitoren oder TR4-assoziierten Molekuelen zur Behandlung von leukaemischen Erkrankungen].
Zenke, M., Bartunek, P., Madruga, J. and Koritschoner, M.P.
WO0333529.
24 April 2003
Mittel zur Behandlung von leukaemischen Erkrankungen.
Zenke, M., Bartunek, P., Madruga, J. and Koritschoner, N.P.
DE10150183A1.
24 April 2003
New coronavirus vaccine and method for designing and obtaining a virus vaccine.
Max Delbrueck Centrum fuer Molekulare in der Helmholtz Gemeinschaft.
EP-4396198-A2.
10 July 2024
LONG-read sequencing of human immunoglobulin gene introns to define a biomarker for in vivo DNA break repair.
Max Delbrueck Centrum fuer Molekulare in der Helmholtz Gemeinschaft.
WO-2024194255-A1.
26 September 2024
New MERS-CoV Vaccine.
Max Delbrueck Centrum fuer Molekulare in der Helmholtz Gemeinschaft.
22164013.9.
27 September 2023
Review
Evolution of 3D chromatin organization at different scales.
Acemel, R.D. and Lupianez, D.G.
Current Opinion in Genetics & Development 78
: 102019.
February 2023
Longevity of the immune response and memory to blood-stage malaria infection.
Achtman, A.H., Bull, P.C., Stephens, R. and Langhorne, J.
Current Topics in Microbiology and Immunology 297
: 71-102.
1 January 2005
Pankreaskarzinom: Kurzfassung der S3-Leitlinie 2007 [Carcinoma of the pancreas: summary of guidelines 2007, issued jointly by 15 German specialist medical societies].
Adler, G., Seufferlein, T., Bischoff, S.C., Brambs, H.J., Feuerbach, S., Grabenbauer, G., Hahn, S., Heinemann, V., Hohenberger, W., Langrehr, J.M., Lutz, M.P., Micke, O., Neuhaus, H., Neuhaus, P., Oettle, H., Schlag, P.M., Schmid, R., Schmiegel, W., Schlottmann, K., Werner, J., Wiedenmann, B. and Kopp, I.
Deutsche Medizinische Wochenschrift 132
(33): 1696-1700.
August 2007
Single-cell and spatial transcriptomics approaches of the bone marrow microenvironment.
Al-Sabah, J., Baccin, C. and Haas, S.
Current Opinion in Oncology 32
(2): 146-153.
1 March 2020
Pressurized intraperitoneal aerosol chemotherapy and its effect on gastric-cancer-derived peritoneal metastases: an overview.
Alberto, M., Brandl, A., Garg, P.K., Gül-Klein, S., Dahlmann, M., Stein, U. and Rau, B.
Clinical and Experimental Metastasis 36
(1): 1-14.
February 2019
The monocyte, a maestro in the tumor microenvironment (TME) of breast cancer.
Amer, H.T., Stein, U. and El Tayebi, H.M.
Cancers 14
(21): 5460.
7 November 2022
Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system.
Amm, I., Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1843
(1): 182-196.
January 2014
Order and disorder: abnormal 3D chromatin organization in human disease.
Anania, C. and Lupianez, D.G.
Briefings in Functional Genomics 19
(2): 128-138.
March 2020
Peer2ref: a peer-reviewer finding web tool that uses author disambiguation.
Andrade-Navarro, M.A., Palidwor, G.A. and Perez-Iratxeta, C.
BioData Mining 5
(1): 14.
7 September 2012
Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells.
Andre, S., Sanchez-Ruderisch, H., Nakagawa, H., Buchholz, M., Kopitz, J., Forberich, P., Kemmner, W., Boeck, C., Deguchi, K., Detjen, K.M., Wiedenmann, B., von Knebel Doeberitz, M., Gress, T.M., Nishimura, S., Rosewicz, S. and Gabius, H.J.
FEBS Journal 274
(13): 3233-3256.
July 2007
Membrane fission by dynamin: what we know and what we need to know.
Antonny, B., Burd, C., De Camilli, P., Chen, E., Daumke, O., Faelber, K., Ford, M., Frolov, V.A., Frost, A., Hinshaw, J.E., Kirchhausen, T., Kozlov, M.M., Lenz, M., Low, H.H., McMahon, H., Merrifield, C., Pollard, T.D., Robinson, P.J., Roux, A. and Schmid, S.
EMBO Journal 35
(21): 2270-2284.
2 November 2016
Management of malignant dysgerminoma of the ovary.
Arndt, T., Taube, E.T., Deubzer, H.E., Rothe, K., Calaminus, G., Sehouli, J. and Pietzner, K.
European Journal of Gynaecological Oncology 43
(2): 353-362.
15 April 2022
Role of type IV secretion in Helicobacter pylori pathogenesis.
Backert, S. and Selbach, M.
Cellular Microbiology 10
(8): 1573-1581.
August 2008
Protein dislocation from the ER.
Bagola, K., Mehnert, M., Jarosch, E. and Sommer, T.
Biochimica et Biophysica Acta - Biomembranes 1808
(3): 925-936.
March 2011
Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment.
Bajic, V.B., Brent, M.R., Brown, R.H., Frankish, A., Harrow, J., Ohler, U., Solovyev, V.V. and Tan, S.L.
Genome Biology 7 Suppl 1
: S3.1-13.
2006
Novel human neurodevelopmental and neurodegenerative disease associated with IRF2BPL gene variants-mechanisms and therapeutic avenues.
Bauersachs, D., Bomholtz, L., Del Ray Mateos, S., Kühn, R. and Lisowski, P.
Frontiers in Neuroscience 18
: 1426177.
6 June 2024
Analysing central metabolism in ultra-high resolution: at the crossroads of carbon and nitrogen.
Bayram, S., Fürst, S., Forbes, M. and Kempa, S.
Molecular Metabolism 33
: 38-47.
19 March 2020
Unwelcome guests – the role of gland-associated Helicobacter pylori infection in gastric carcinogenesis.
Beccaceci, G. and Sigal, M.
Frontiers in Oncology 13
: 1171003.
21 April 2023
Pancreatic cancer models for translational research.
Behrens, D., Walther, W. and Fichtner, I.
Pharmacology & Therapeutics 173
: 146-158.
May 2017
Sentinel lymph node biopsy for gastrointestinal cancers.
Bembenek, A., Gretschel, S. and Schlag, P.M.
Journal of Surgical Oncology 96
(4): 342-352.
15 September 2007
Technique and clinical consequences of sentinel lymph node biopsy in colorectal cancer.
Bembenek, A., String, A., Gretschel, S. and Schlag, P.M.
Surgical Oncology 17
(3): 183-193.
September 2008
Mesenchymal stromal cells (MSCs): science and f(r)iction.
Bieback, K., Wuchter, P., Besser, D., Franke, W., Becker, M., Ott, M., Pacher, M., Ma, N., Stamm, C., Klueter, H., Mueller, A. and Ho, A.D.
Journal of Molecular Medicine 90
(7): 773-782.
July 2012
SARS-CoV-2 in humans.
Binder, M. and Wyler, E.
Berliner und Munchener Tierarztliche Wochenschrift 134
: 1-13.
30 April 2021
Molecular aspects of mesenchymal-epithelial interactions.
Birchmeier, C. and Birchmeier, W.
Annual Review of Cell Biology 9
: 511-540.
1993
Met, metastasis, motility and more.
Birchmeier, C., Birchmeier, W., Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4
(12): 915-925.
December 2003
Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness.
Birchmeier, W. and Behrens, J.
Biochimica et Biophysica Acta 1198
(1): 11-26.
27 May 1994
SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction.
Birge, R.B., Knudsen, B.S., Besser, D. and Hanafusa, H.
Genes to Cells 1
(7): 595-613.
July 1996
Cytochrome P450 biosensors - a review.
Bistolas, N., Wollenberger, U., Jung, C. and Scheller, F.W.
Biosensors and Bioelectronics 20
(12): 2408-2423.
1 January 2005
Do autochthonous tumors interfere with effector T cell responses?
Blankenstein, T.
Seminars in Cancer Biology 17
(4): 267-274.
August 2007
The role of tumor stroma in the interaction between tumor and immune system.
Blankenstein, T.
Current Opinion in Immunology 17
(2): 180-186.
1 January 2005
Genetic approaches to cancer immunotherapy.
Blankenstein, T., Cayeux, S. and Qin, Z.
Reviews of Physiology Biochemistry and Pharmacology 129
: 1-49.
1 January 1996
Targeting cancer-specific mutations by T cell receptor gene therapy.
Blankenstein, T., Leisegang, M., Uckert, W. and Schreiber, H.
Current Opinion in Immunology 33
: 112-119.
April 2015
Chemical carcinogens as foreign bodies and some pitfalls regarding cancer immune surveillance.
Blankenstein, T. and Qin, Z.
Advances in Cancer Research 90
: 179-207.
2003
The role of IFN-gamma in tumor transplantation immunity and inhibition of chemical carcinogenesis.
Blankenstein, T. and Qin, Z.H.
Current Opinion in Immunology 15
(2): 148-154.
April 2003
Epigenetic therapy: azacytidine and decitabine in acute myeloid leukemia.
Bohl, S.R., Bullinger, L. and Rücker, F.G.
Expert Review of Hematology 11
(5): 361-371.
May 2018
Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia.
Bosanquet, A.G., Sturm, I., Wieder, T., Essmann, F., Bosanquet, M.I., Head, F.J., Doerken, B. and Daniel, P.T.
Leukemia 16
(6): 1035-1044.
June 2002
Oncogene-induced senescence: putting the brakes on tumor development.
Braig, M. and Schmitt, C.A.
Cancer Research 66
(6): 2881-2884.
15 March 2006
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin.
Brembeck, F.H., Rosario, M. and Birchmeier, W.
Current Opinion in Genetics & Development 16
(1): 51-59.
February 2006
mRNAs, proteins and the emerging principles of gene expression control.
Buccitelli, C. and Selbach, M.
Nature Reviews Genetics 21
(10): 630-644.
October 2020
Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.
Buchberger, A., Bukau, B. and Sommer, T.
Molecular Cell 40
(2): 238-252.
22 October 2010
Decoding and targeting the molecular basis of MACC1-driven metastatic spread: lessons from big data mining and clinical-experimental approaches.
Budczies, J., Kluck, K., Walther, W. and Stein, U.
Seminars in Cancer Biology 60
: 365-379.
February 2020
New avenues for genetics guided therapeutic approaches in AML.
Bullinger, L.
Acta Haematologica Polonica 45
(4): 322-329.
1 October 2014
Genomics of acute myeloid leukemia diagnosis and pathways.
Bullinger, L., Döhner, K. and Döhner, H.
Journal of Clinical Oncology 35
(9): 934-946.
20 March 2017
Non-coding RNAs: lncRNAs, miRNAs, and piRNAs in sexual development.
Burgos, M., Hurtado, A., Jiménez, R. and Barrionuevo, F.J.
Sexual Development 15
(5-6): 335-350.
December 2021
Translational control of gene expression and disease.
Calkhoven, C.F., Mueller, C. and Leutz, A.
Trends in Molecular Medicine 8
(12): 577-583.
1 December 2002
Beyond read-counts: Ribo-seq data analysis to understand the functions of the transcriptome.
Calviello, L. and Ohler, U.
Trends in Genetics 33
(10): 728-744.
October 2017
Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63
(6): 918-925.
15 September 2016
Current and future treatment strategies for rhabdomyosarcoma.
Chen, C., Dorado-Garcia, H., Scheer, M. and Henssen, A.G.
Frontiers in Oncology 9
: 1458.
20 December 2019
Mechanisms of substrate processing during ER-associated protein degradation.
Christianson, J.C., Jarosch, E. and Sommer, T.
Nature Reviews Molecular Cell Biology 24
(11): 777-796.
November 2023
Cancer evolution: a multifaceted affair.
Ciriello, G., Magnani, L., Aitken, S.J., Akkari, L., Behjati, S., Hanahan, D., Landau, D.A., Lopez-Bigas, N., Lupiáñez, D.G., Marine, J.C., Martin-Villalba, A., Natoli, G., Obenauf, A.C., Oricchio, E., Scaffidi, P., Sottoriva, A., Swarbrick, A., Tonon, G., Vanharanta, S. and Zuber, J.
Cancer Discovery 14
: 1-13.
January 2024
Functional insights into pathogen biology from 3D electron microscopy.
Cyrklaff, M., Frischknecht, F. and Kudryashev, M.
FEMS Microbiology Reviews 41
(6): 828-853.
1 November 2017
S100A4 in cancer metastasis: Wnt signaling-driven interventions for metastasis restriction.
Dahlmann, M., Kobelt, D., Walther, W., Mudduluru, G. and Stein, U.
Cancers 8
(6): 59.
20 June 2016
Apoptolidin: Induction of apoptosis by a natural product.
Daniel, P.T., Koert, U. and Schuppan, J.
Angewandte Chemie International Edition 45
: 872-893.
30 January 2006
Guardians of cell death: the Bcl-2 family proteins.
Daniel, P.T., Schulze-Osthoff, K., Belka, C. and Guener, D.
Essays in Biochemistry 39
: 73-88.
1 October 2003
Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily.
Daumke, O. and Praefcke, G.J.
Biopolymers 105
(8): 580-593.
August 2016
BAR domain scaffolds in dynamin-mediated membrane fission.
Daumke, O., Roux, A. and Haucke, V.
Cell 156
(5): 882-892.
27 February 2014
Personalisierte Medizin in der Kinderonkologie: Wo stehen wir heute?
Deubzer, H.E., Schulte, J.H. and Eggert, A.
TumorDiagnostik & Therapie 43
(01): 29-44.
February 2022
Personalisierte Medizin in der Kinderonkologie: Wo stehen wir heute?
Deubzer, H.E., Schulte, J.H. and Eggert, A.
Pädiatrie up2date 16
(4): 325-342.
December 2021
Mannose receptor-mediated gene delivery into antigen presenting dendritic cells.
Diebold, S.S., Plank, C., Cotten, M., Wagner, E. and Zenke, M.
Somatic Cell and Molecular Genetics 27
(1-6): 65-74.
November 2002
Literature review: potential non-thermal molecular effects of external radiofrequency electromagnetic fields on cancer.
Dieper, A., Scheidegger, S., Füchslin, R.M., Veltsista, P.D., Stein, U., Weyland, M., Gerster, D., Beck, M., Bengtsson, O., Zips, D. and Ghadjar, P.
International Journal of Hyperthermia 41
(1): 2379992.
17 July 2024
Targeting B cells and microglia in multiple sclerosis with Bruton tyrosine kinase inhibitors: a review.
Dybowski, S., Torke, S. and Weber, M.S.
JAMA Neurology 80
(4): 404-414.
1 April 2023
Diverse effects of obesity on antitumor immunity and immunotherapy.
Dyck, L. and Lynch, L.
Trends in Molecular Medicine 29
(2): 112-123.
February 2023
The EHA Research Roadmap: Malignant Myeloid Diseases.
Döhner, H., Malcovati, L., Ossenkoppele, G.J., Hochhaus, A., Maria Vannucchi, A., Bullinger, L., Cervantes, F., Craddock, C., de Witte, T., Döhner, K., Dombret, H., Fenaux, P., Geissler, J., Germing, U., Guilhot, F., Harrison, C., Hellström-Lindberg, E., Passamonti, F., Sierra, J., Skoda, R. and Wierzbowska, A.
HemaSphere 5
(9): e635.
September 2021
Genome-engineering technologies for modeling and treatment of cystic fibrosis.
Dębczyński, M., Mojsak, D., Minarowski, Ł., Maciejewska, M., Lisowski, P. and Mróz, R.M.
Advances in Medical Sciences 68
(1): 111-120.
March 2023
Thymoquinone: a tie-breaker in SARS-CoV2-infected cancer patients?
Elgohary, S., Elkhodiry, A.A., Amin, N.S., Stein, U. and El Tayebi, H.M.
Cells 10
(2): 302.
2 February 2021
Redirecting T lymphocyte specificity by T cell receptor gene transfer - a new era for immunotherapy.
Engels, B. and Uckert, W.
Molecular Aspects of Medicine 28
(1): 115-142.
February 2007
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Fabricius, E.M., Kruse-Boitschenko, U., Khoury, R., Wildner, G.P., Raguse, J.D. and Klein, M.
International Journal of Oncology 34
(5): 1257-1279.
May 2009
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Fabricius, E.M., Kruse-Boitschenko, U., Khoury, R., Wildner, G.P., Raguse, J.D., Klein, M. and Hoffmeister, B.
International Journal of Oncology 35
(6): 1377-1394.
December 2009
Structural insights into dynamin-mediated membrane fission.
Faelber, K., Held, M., Gao, S., Posor, Y., Haucke, V., Noe, F. and Daumke, O.
Structure 20
(10): 1621-1628.
10 October 2012
Struktur und Funktion des mechanochemischen Motorproteins Dynamin.
Faelber, K. and Daumke, O.
BIOspektrum 24
(5): 481-483.
September 2018
Oligomerization of dynamin superfamily proteins in health and disease.
Faelber, K., Gao, S., Held, M., Posor, Y., Haucke, V., Noé, F. and Daumke, O.
Progress in Molecular Biology and Translational Science 117
: 411-443.
2013
The translational potential of microRNAs as biofluid markers of urological tumours.
Fendler, A., Stephan, C., Yousef, G.M., Kristiansen, G. and Jung, K.
Nature Reviews Urology 13
(12): 734-752.
December 2016
The role of Wnt and R-spondin in the stomach during health and disease.
Fischer, A.S. and Sigal, M.
Biomedicines 7
(2): 44.
19 June 2019
Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D., Luft, F.C., Bader, M., Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90
(5): 495-508.
May 2012
Circular RNAs: a new class of biomarkers as a rising interest in laboratory medicine.
Franz, A., Rabien, A., Stephan, C., Ralla, B., Fuchs, S., Jung, K. and Fendler, A.
Clinical Chemistry and Laboratory Medicine 56
(12): 1992-2003.
December 2018
Protein biomarkers in blood reflect the interrelationships between stroke outcome, inflammation, coagulation, adhesion, senescence and cancer.
Fuellen, G., Walter, U., Henze, L., Böhmert, J., Palmer, D., Lee, S., Schmitt, C.A., Rudolf, H. and Kowald, A.
Cellular and Molecular Neurobiology 43
(4): 1413-1424.
May 2023
Next-generation in vivo modeling of human cancers.
Gargiulo, G.
Frontiers in Oncology 8
: 429.
October 2018
Epigenomic profiling of cancer cells.
Gargiulo, G. and Minucci, S.
International Journal of Biochemistry and Cell Biology 41
(1): 127-135.
January 2009
Wie Kochsalz Mitochondrien beeinflusst.
Geisberger, S.
BIOspektrum 28
(4): 387-389.
June 2022
Tissue macrophage identity and self-renewal.
Gentek, R., Molawi, K. and Sieweke, M.H.
Immunological Reviews 262
(1): 56-73.
November 2014
Targeting MET in cancer: rationale and progress.
Gherardi, E., Birchmeier, W., Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12
(2): 89-103.
February 2012
Cellular senescence: defining a path forward.
Gorgoulis, V., Adams, P.D., Alimonti, A., Bennett, D.C., Bischof, O., Bishop, C., Campisi, J., Collado, M., Evangelou, K., Ferbeyre, G., Gil, J., Hara, E., Krizhanovsky, V., Jurk, D., Maier, A.B., Narita, M., Niedernhofer, L., Passos, J.F., Robbins, P.D., Schmitt, C.A., Sedivy, J., Vougas, K., von Zglinicki, T., Zhou, D., Serrano, M. and Demaria, M.
Cell 179
(4): 813-827.
31 October 2019
Minimalresiduale Tumorerkrankung bei gastrointestinalen Karzinomen : Prognoserelevanz und onkologisch-chirurgische Konsequenzen [Minimal residual tumor in gastrointestinal carcinoma: Relevance to prognosis and oncologic surgical consequences].
Gretschel, S., Bembenek, A., Schulze, T., Kemmner, W. and Schlag, P.M.
Chirurg 77
(12): 1104-1117.
1 December 2006
New concepts of staging in gastrointestinal tumors as a basis of diagnosis and multimodal therapy.
Gretschel, S., Moesta, K.T., Huenerbein, M., Lange, T., Gebauer, B., Stroszczinski, C., Bembenek, A. and Schlag, P.M.
Onkologie 27
(1): 23-30.
February 2004
Molecular signaling mechanisms of axon-glia communication in the peripheral nervous system.
Grigoryan, T. and Birchmeier, W.
BioEssays 37
(5): 502-513.
May 2015
Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
Grigoryan, T., Wend, P., Klaus, A. and Birchmeier, W.
Genes & Development 22
(17): 2308-2341.
1 September 2008
The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S., Rosario, M., Birchmeier, C. and Birchmeier, W.
Advances in Cancer Research 106
: 53-89.
2010
Protein production and purification.
Gräslund, S., Nordlund, P., Weigelt, J., Hallberg, M., Bray, J., Gileadi, O., Knapp, S., Oppermann, U., Arrowsmith, C., Hui, R., Ming, J., dhe-Paganon, S., Park, H.W., Savchenko, A., Yee, A., Edwards, A., Vincentelli, R., Cambillau, C., Kim, R., Kim, S.H., Rao, Z., Shi, Y., Terwilliger, T.C., Kim, C.Y., Hung, L.W., Waldo, G.S., Peleg, Y., Albeck, S., Unger, T., Dym, O., Prilusky, J., Sussman, J.L., Stevens, R.C., Lesley, S.A., Wilson, I.A., Joachimiak, A., Collart, F., Dementieva, I., Donnelly, M.I., Eschenfeldt, W.H., Kim, Y.M., Stols, L., Wu, R., Zhou, M., Burley, S.K., Emtage, J.S., Sauder, J.M., Thompson, D., Bain, K., Luz, J., Gheyi, T., Zhang, F., Atwell, S., Almo, S.C., Bonanno, J.B., Fiser, A., Swaminathan, S., Studier, F.W., Chance, M.R., Sali, A., Acton, T.B., Xiao, R., Zhao, L., Ma, L.C., Hunt, J.F., Tong, L., Cunningham, K., Inouye, M., Anderson, S., Janjua, H., Shastry, R., Ho, C.K., Wang, D., Wang, H., Jiang, M., Montelione, G.T., Stuart, D.I., Owens, R.J., Daenke, S., Schütz, A., Heinemann, U., Yokoyama, S., Büssow, K. and Gunsalus, K.C.
Nature Methods 5
(2): 135-146.
February 2008
Sarcoma treatment in the era of molecular medicine.
Grünewald, T.G.P., Alonso, M., Avnet, S., Banito, A., Burdach, S., Cidre-Aranaz, F., Di Pompo, G., Distel, M., Dorado-Garcia, H., Garcia-Castro, J., González-González, L., Grigoriadis, A.E., Kasan, M., Koelsche, C., Krumbholz, M., Lecanda, F., Lemma, S., Longo, D.L., Madrigal-Esquivel, C., Morales-Molina, Á., Musa, J., Ohmura, S., Ory, B., Pereira-Silva, M., Perut, F., Rodriguez, R., Seeling, C., Al Shaaili, N., Shaabani, S., Shiavone, K., Sinha, S., Tomazou, E.M., Trautmann, M., Vela, M., Versleijen-Jonkers, Y.M.H., Visgauss, J., Zalacain, M., Schober, S.J., Lissat, A., English, W.R., Baldini, Ni. and Heymann, D.
EMBO Molecular Medicine 12
: e11131.
6 November 2020
Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside?
Guedan, S., Luu, M., Ammar, D., Barbao, P., Bonini, C., Bousso, P., Buchholz, C.J., Casucci, M., De Angelis, B., Donnadieu, E., Espie, D., Greco, B., Groen, R., Huppa, J.B., Kantari-Mimoun, C., Laugel, B., Mantock, M., Markman, J.L., Morris, E., Quintarelli, C., Rade, M., Reiche, K., Rodriguez-Garcia, A., Rodriguez-Madoz, J.R., Ruggiero, E., Themeli, M., Hudecek, M. and Marchiq, I.
Journal for ImmunoTherapy of Cancer 10
(5): e003487.
May 2022
Developmental and functional heterogeneity of monocytes.
Guilliams, M., Mildner, A. and Yona, S.
Immunity 49
(4): 595-613.
16 October 2018
Mechanosurveillance: Tiptoeing T cells.
Göhring, J., Schrangl, L., Schütz, G.J. and Huppa, J.B.
Frontiers in Immunology 13
: 886328.
26 May 2022
Hematopoietic stem cells in health and disease - insights from single-cell multi-omic approaches.
Haas, S.
Current Stem Cell Reports 6
(3): 67-76.
September 2020
Causes and consequences of hematopoietic stem cell heterogeneity.
Haas, S., Trumpp, A. and Milsom, M.D.
Cell Stem Cell 22
(5): 627-638.
3 May 2018
Karzinogenese: Big Bang oder kontinuierliche Evolution?
Haase, K. and Schwarz, R.F.
BIOspektrum 26
(7): 718-720.
November 2020
Single-cell multi-omics and lineage tracing to dissect cell fate decision-making.
Haghverdi, L. and Ludwig, L.S.
Stem Cell Reports 18
(1): 13-25.
10 January 2023
Refining AML treatment: the role of genetics in response and resistance evaluation to new agents.
Halik, A., Arends, C.M., Bullinger, L., Damm, F. and Frick, M.
Cancers 14
(7): 1689.
26 March 2022
Dynamin-like MxA GTPase: Structural insights into oligomerization and implications for antiviral activity.
Haller, O., Gao, S., von der Malsburg, A., Daumke, O. and Kochs, G.
Journal of Biological Chemistry 285
(37): 28419-28424.
10 September 2010
Finding the will and the way of ERAD substrate retrotranslocation.
Hampton, R.Y. and Sommer, T.
Current Opinion in Cell Biology 24
(4): 460-466.
August 2012
Microbe-driven genotoxicity in gastrointestinal carcinogenesis.
Hartl, K. and Sigal, M.
International Journal of Molecular Sciences 21
(20): 7439.
2 October 2020
Facilities and methods for the high-throughput crystal structural analysis of human proteins.
Heinemann, U., Buessow, K., Mueller, U. and Umbach, P.
Accounts of Chemical Research 36
(3): 157-163.
March 2003
Establishing a structural genomics platform: The Berlin-based Protein Structure Factory.
Heinemann, U.
Gene Function and Disease 3
(1-2): 25-32.
October 2002
The Berlin "protein structure factory" initiative: a technology-oriented approach to structural genomics.
Heinemann, U.
Ernst Schering Research Foundation Workshop 34
: 101-121.
2001
Cold-shock domains - abundance, structure, properties, and nucleic-acid binding.
Heinemann, U. and Roske, Y.
Cancers 13
(2): 190.
7 January 2021
Symmetry in nucleic-acid double helices.
Heinemann, U. and Roske, Y.
Symmetry 12
(5): 737.
5 May 2020
Structural features of tight-junction proteins.
Heinemann, U. and Schuetz, A.
International Journal of Molecular Sciences 20
(23): 6020.
29 November 2019
Emerging functions of DNA transposases and oncogenic mutators in childhood cancer development.
Henssen, A.G. and Kentsis, A.
JCI Insight 3
(20): 123172.
18 October 2018
Recent advances in precision medicine for acute myeloid leukemia.
Hernández-Sánchez, A. and Bullinger, L.
Current Opinion in Oncology 35
(6): 581-588.
November 2023
Clinical research and industrial sponsoring: avenues towards transparency and credibility.
Hildebrandt, M. and Ludwig, W.D.
Onkologie 26
: 529-534.
1 December 2003
It takes two to tango: IκBs, the multifunctional partners of NF-κB.
Hinz, M., Coel Arslan, S. and Scheidereit, C.
Immunological Reviews 246
(1): 59-76.
March 2012
The IκB kinase complex in NF-κB regulation and beyond.
Hinz, M. and Scheidereit, C.
EMBO Reports 15
(1): 46-61.
1 January 2014
The ubiquitylation machinery of the endoplasmic reticulum.
Hirsch, C., Gauss, R., Horn, S.C., Neuber, O. and Sommer, T.
Nature 458
(7237): 453-460.
26 March 2009
Coping with stress: cellular relaxation techniques.
Hirsch, C., Gauss, R. and Sommer, T.
Trends in Cell Biology 16
(12): 657-663.
December 2006
Endoplasmic reticulum-associated protein degradation - one model fits all?
Hirsch, C., Jarosch, E., Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1695
(1-3): 215-223.
1 January 2004
Building functional modules from molecular interactions.
Hofmann, K.P., Spahn, C.M.T., Heinrich, R. and Heinemann, U.
Trends in Biochemical Sciences 31
(9): 497-508.
September 2006
Gastric cancer.
Hohenberger, P. and Gretschel, S.
Lancet 362
: 305-315.
1 January 2003
Mit Einzelzell-Genomik die Entscheidungen von Zellen verfolgen [Deciphering cell fate decisions using single cell genomics].
Hu, B. and Junker, J.P.
BIOspektrum 27
(1): 25-27.
February 2021
Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib.
Huelsmann, H.J., Rolff, J., Bender, C., Jarahian, M., Korf, U., Herwig, R., Froehlich, H., Thomas, M., Merk, J., Fichtner, I., Sueltmann, H. and Kuner, R.
Lung Cancer 86
(2): 151-157.
November 2014
Targeting the tumor microenvironment of leukemia and lymphoma.
Höpken, U.E. and Rehm, A.
Trends in Cancer 5
(6): 351-364.
June 2019
Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs.
Höpken, U.E. and Rehm, A.
Journal of Molecular Medicine 90
(11): 1237-1245.
November 2012
Transposons for gene therapy!
Ivics, Z. and Izsvak, Z.
Current Gene Therapy 6
(5): 593-607.
October 2006
Use of vibrational spectroscopy to study protein and DNA structure, hydration, and binding of biomolecules: A combined theoretical and experimental approach.
Jalkanen, K.J., Wuertz-Juergensen, V., Claussen, A., Rahim, A., Jensen, G.M., Wade, R.C., Nardi, F., Jung, C., Degtyarenko, I.M., Nieminen, R.M., Herrmann, F., Knapp-Mohammady, M., Niehaus, T.A., Frimand, K. and Suhai, S.
International Journal of Quantum Chemistry 106
(5): 1160-1198.
27 January 2006
Endoplasmic reticulum-associated protein degradation.
Jarosch, E., Lenk, U. and Sommer, T.
International Review of Cytology 223
: 39-81.
2003
Bevacizumab in temozolomide refractory high-grade gliomas: single-centre experience and review of the literature.
Jeck, J., Kassubek, R., Coburger, J., Edenhofer, S., Schönsteiner, S.S., Ludolph, A.C., Schmitz, B., Engelke, J., Mayer-Steinacker, R., Lewerenz, J. and Bullinger, L.
Therapeutic Advances in Neurological Disorders 11
: 1756285617753597.
21 January 2018
NF-κB in cellular senescence and cancer treatment.
Jing, H. and Lee, S.
Molecules and Cells 37
(3): 189-195.
31 March 2014
Notch signaling in leukemias and lymphomas.
Jundt, F., Schwarzer, R. and Doerken, B.
Current Molecular Medicine 8
(1): 51-59.
February 2008
About oxygen, cytochrome p450 and titanium: learning from ron estabrook.
Jung, C.
Drug Metabolism Reviews 39
(2-3): 501-513.
2007
Freeze-quenched iron-oxo intermediates in cytochromes P450.
Jung, C., Schuenemann, V. and Lendzian, F.
Biochemical and Biophysical Research Communications 338
(1): 355-364.
29 August 2005
Every cell is special: genome-wide studies add a new dimension to single-cell biology.
Junker, J.P. and van Oudenaarden, A.
Cell 157
(1): 8-11.
27 March 2014
DNA repair and antibody diversification: the 53BP1 paradigm.
Kabrani, E., Saha, T. and Di Virgilio, M.
Trends in Immunology 44
(10): 782-791.
October 2023
Genome wide conditional mouse knockout resources.
Kaloff, C., Anastassiadis, K., Ayadi, A., Baldock, R., Beig, J., Birling, M.C., Bradley, A., Brown, S.D.M., Buerger, A., Bushell, W., Chiani, F., Collins, F.S., Doe, B., Eppig, J.T., Finnell, R.H., Fletcher, C., Flicek, P., Fray, M., Friedel, R.H., Gambadoro, A., Gates, H., Hansen, J., Herault, Y., Hicks, G.G., Hoerlein, A., Hrabe de Angelis, M., Iyer, V., de Jong, P.J., Koscielny, G., Kuehn, R., Liu, P., Lloyd, K.C.K, Lopez, R.G., Marschall, S., Martinez, S., McKerlie, C., Meehan, T., von Melchner, H., Moore, M., Murray, S.A., Nagy, A., Nutter, L.M.J., Pavlovic, G., Pombero, A., Prosser, H., Ramirez-Solis, R., Ringwald, M., Rosen, B., Rosenthal, N., Rossant, J., Ruiz Noppinger, P., Ryder, E., Skarnes, W.C., Schick, J., Schnuetgen, F., Schofield, P., Seisenberger, C., Selloum, M., Smedley, D., Simpson, E.M., Stewart, A.F., Teboul, L., Tocchini Valentini, G.P., Valenzuela, D., West, A.P. and Wurst, W.
Drug Discovery Today: Disease Models 20
: 3-12.
2016
Small molecule inhibitors for hepatocellular carcinoma: advances and challenges.
Kamal, M.A., Mandour, Y.M., Abd El-Aziz, M.K., Stein, U. and El Tayebi, H.M.
Molecules 27
(17): 5537.
1 September 2022
Immunotherapy: target the stroma to hit the tumor.
Kammertoens, T., Schueler, T. and Blankenstein, T.
Trends in Molecular Medicine 11
(5): 225-231.
1 January 2005
FTIR studies of the redox partner interaction in cytochrome P450: The Pdx-P450cam couple.
Karyakin, A., Motiejunas, T., Wade, R.C. and Jung, C.
Biochimica et Biophysica Acta - General Subjects 1770
(3): 420-431.
March 2007
Enhanced T cell receptor gene therapy for cancer.
Kieback, E. and Uckert, W.
Expert Opinion on Biological Therapy 10
(5): 749-762.
May 2010
Wnt signalling and its impact on development and cancer.
Klaus, A. and Birchmeier, W.
Nature Reviews Cancer 8
(5): 387-398.
May 2008
Choosing wisely - Preclinical test models in the era of precision medicine.
Klinghammer, K., Walther, W. and Hoffmann, J.
Cancer Treatment Reviews 55
: 36-45.
April 2017
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky, D.J., Abdel-Aziz, A.K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M.H., Abudu, Y.P., Acevedo-Arozena, A., Adamopoulos, I.E., Adeli, K., Adolph, T.E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B.B., Agnello, M., Agostinis, P., Agrewala, J.N., Agrotis, A., Aguilar, P.V., Ahmad, S.T., Ahmed, Z.M., Ahumada-Castro, U., Aits, S., Aizawa, S., Akkoc, Y., Akoumianaki, T., Akpinar, H.A., Al-Abd, A.M., Al-Akra, L., Al-Gharaibeh, A., Alaoui-Jamali, M.A., Alberti, S., Alcocer-Gómez, E., Alessandri, C., Ali, M., Alim Al-Bari, M.A., Aliwaini, S., Alizadeh, J., Almacellas, E., Almasan, A., Alonso, A., Alonso, G.D., Altan-Bonnet, N., Altieri, D.C., Álvarez, E.M.C., Alves, S., Alves da Costa, C., Alzaharna, M.M., Amadio, M., Amantini, C., Amaral, C., Ambrosio, S., Amer, A.O., Ammanathan, V., An, Z., Andersen, S.U., Andrabi, S.A., Andrade-Silva, M., Andres, A.M., Angelini, S., Ann, D., Anozie, U.C., Ansari, M.Y., Antas, P., Antebi, A., Antón, Z., Anwar, T., Apetoh, L., Apostolova, N., Araki, T., Araki, Y., Arasaki, K., Araújo, W.L., Araya, J., Arden, C., Arévalo, M.A., Arguelles, S., Arias, E., Arikkath, J., Arimoto, H., Ariosa, A.R., Armstrong-James, D., Arnauné-Pelloquin, L., Aroca, A., Arroyo, D.S., Arsov, I., Artero, R., Asaro, D.M.L., Aschner, M., Ashrafizadeh, M., Ashur-Fabian, O., Atanasov, A.G., Au, A.K., Auberger, P., Auner, H.W., Aurelian, L., Autelli, R., Avagliano, L., Ávalos, Y., Aveic, S., Aveleira, C.A., Avin-Wittenberg, T., Aydin, Y., Ayton, S., Ayyadevara, S., Azzopardi, M., Baba, M.u, Backer, J.M., Backues, S.K., Bae, D.H., Bae, O.N., Bae, S.H., Baehrecke, E.H., Baek, A., Baek, S.H., Baek, S.H., Bagetta, G., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X., Bai, Y., Bairagi, N., Baksi, S., Balbi, T., Baldari, C.T., Balduini, W., Ballabio, A., Ballester, M., Balazadeh, S., Balzan, R., Bandopadhyay, R., Banerjee, S., Banerjee, S., Bánréti, A., Bao, Y., Baptista, M.S., Baracca, A., Barbati, C., Bargiela, A., Barilà, D., Barlow, P.G., Barmada, S.J., Barreiro, E., Barreto, G.E., Bartek, J., Bartel, B., Bartolome, A., Barve, G.R., Basagoudanavar, S.H., Bassham, D.C., Bast, R.C., Basu, A., Batoko, H., Batten, I., Baulieu, E.E., Baumgarner, B.L., Bayry, J., Beale, R., Beau, I., Beaumatin, F., Bechara, L.R.G., Beck, G.R., Beers, M.F., Begun, J., Behrends, C., Behrens, G.M.N., Bei, R., Bejarano, E., Bel, S., Behl, C., Belaid, A., Belgareh-Touzé, N., Bellarosa, C., Belleudi, F., Belló Pérez, M., Bello-Morales, R., Beltran, J.S.O., Beltran, S., Benbrook, D.M., Bendorius, M., Benitez, B.A., Benito-Cuesta, I., Bensalem, J., Berchtold, M.W., Berezowska, S., Bergamaschi, D., Bergami, M., Bergmann, A., Berliocchi, L., Berlioz-Torrent, C., Bernard, A., Berthoux, L., Besirli, C.G., Besteiro, S., Betin, V.M., Beyaert, R., Bezbradica, J.S., Bhaskar, K., Bhatia-Kissova, I., Bhattacharya, R., Bhattacharya, S., Bhattacharyya, S., Bhuiyan, M.S., Bhutia, S.K., Bi, L., Bi, X., Biden, T.J., Bijian, K., Billes, V.A., Binart, N., Bincoletto, C., Birgisdottir, A.B., Bjorkoy, G., Blanco, G., Blas-Garcia, A., Blasiak, J., Blomgran, R., Blomgren, K., Blum, J.S., Boada-Romero, E., Boban, M., Boesze-Battaglia, K., Boeuf, P., Boland, B., Bomont, P., Bonaldo, P., Bonam, S.R., Bonfili, L., Bonifacino, J.S., Boone, B.A., Bootman, M.D., Bordi, M., Borner, C., Bornhauser, B.C., Borthakur, G., Bosch, J., Bose, S., Botana, L.M., Botas, J., Boulanger, C.M., Boulton, M.E., Bourdenx, M., Bourgeois, B., Bourke, N.M., Bousquet, G., Boya, P., Bozhkov, P.V., Bozi, L.H.M., Bozkurt, T.O., Brackney, D.E., Brandts, C.H., Braun, R.J., Braus, G.H., Bravo-Sagua, R., Bravo-San Pedro, J.M., Brest, P., Bringer, M.A., Briones-Herrera, A., Broaddus, V.C., Brodersen, P., Brodsky, J.L., Brody, S.L., Bronson, P.G., Bronstein, J.M., Brown, C.N., Brown, R.E., Brum, P.C., Brumell, J.H., Brunetti-Pierri, N., Bruno, D., Bryson-Richardson, R.J., Bucci, C., Buchrieser, C., Bueno, M., Buitrago-Molina, L.E., Buraschi, S., Buch, S., Buchan, J.R., Buckingham, E.M., Budak, H., Budini, M., Bultynck, G., Burada, F., Burgoyne, J.R., Burón, M.I., Bustos, V., Büttner, S., Butturini, E., Byrd, A., Cabas, I., Cabrera-Benitez, S., Cadwell, K., Cai, J., Cai, L., Cai, Q., Cairó, M., Calbet, J.A., Caldwell, G.A., Caldwell, K.A., Call, J.A., Calvani, R., Calvo, A.C., Calvo-Rubio Barrera, M., Camara, N.O., Camonis, J.H., Camougrand, N., Campanella, M., Campbell, E.M., Campbell-Valois, F.X., Campello, S., Campesi, I., Campos, J.C., Camuzard, O., Cancino, J., Candido de Almeida, D., Canesi, L., Caniggia, I., Canonico, B., Cantí, C., Cao, B., Caraglia, M., Caramés, B., Carchman, E.H., Cardenal-Muñoz, E., Cardenas, C., Cardenas, L., Cardoso, S.M., Carew, J.S., Carle, G.F., Carleton, G., Carloni, S., Carmona-Gutierrez, D., Carneiro, L.A., Carnevali, O., Carosi, J.M., Carra, S., Carrier, A., Carrier, L., Carroll, B., Carter, A.B., Carvalho, A.N., Casanova, M., Casas, C., Casas, J., Cassioli, C., Castillo, E.F., Castillo, K., Castillo-Lluva, S., Castoldi, F., Castori, M., Castro, A.F., Castro-Caldas, M., Castro-Hernandez, J., Castro-Obregon, S., Catz, S.D., Cavadas, C., Cavaliere, F., Cavallini, G., Cavinato, M., Cayuela, M.L., Cebollada Rica, P., Cecarini, V., Cecconi, F., Cechowska-Pasko, M., Cenci, S., Ceperuelo-Mallafré, V., Cerqueira, J.J., Cerutti, J.M., Cervia, D., Cetintas, V.B., Cetrullo, S., Chae, H.J., Chagin, A.S., Chai, C.Y., Chakrabarti, G., Chakrabarti, O., Chakraborty, T., Chakraborty, T., Chami, M., Chamilos, G., Chan, D.W., Chan, E.Y.W., Chan, E.D., Chan, H.Y.E., Chan, H.H., Chan, H., Chan, M.T.V., Chan, Y.S., Chandra, P.K., Chang, C.P., Chang, C., Chang, H.C., Chang, K., Chao, J., Chapman, T., Charlet-Berguerand, N., Chatterjee, S., Chaube, S.K., Chaudhary, A., Chauhan, S., Chaum, E., Checler, F., Cheetham, M.E., Chen, C.S., Chen, G.C., Chen, J.F., Chen, L.L., Chen, L., Chen, L., Chen, M., Chen, M.K., Chen, N., Chen, Q., Chen, R.H., Chen, S., Chen, W., Chen, W., Chen, X.M., Chen, X.W., Chen, X., Chen, Y., Chen, Y.G., Chen, Y., Chen, Y., Chen, Y.J., Chen, Y.Q., Chen, Z.S., Chen, Z., Chen, Z.H., Chen, Z.J., Chen, Z., Cheng, H., Cheng, J., Cheng, S.Y., Cheng, W., Cheng, X., Cheng, X.T., Cheng, Y., Cheng, Z., Chen, Z., Cheong, H., Cheong, J.K., Chernyak, B.V., Cherry, S., Cheung, C.F.R., Cheung, C.H.A., Cheung, K.H., Chevet, E., Chi, R.J., Chiang, A.K.S., Chiaradonna, F., Chiarelli, R., Chiariello, M., Chica, N., Chiocca, S., Chiong, M., Chiou, S.H., Chiramel, A.I., Chiurchiù, V., Cho, D.H., Choe, S.K., Choi, A.M.K., Choi, M.E., Choudhury, K.R., Chow, N.S., Chu, C.T., Chua, J.P., Chua, J.J.E., Chung, H., Chung, K.P., Chung, S., Chung, S.H., Chung, Y.L., Cianfanelli, V., Ciechomska, I.A., Cifuentes, M., Cinque, L., Cirak, S., Cirone, M., Clague, M.J., Clarke, R., Clementi, E., Coccia, E.M., Codogno, P., Cohen, E., Cohen, M.M, Colasanti, T., Colasuonno, F., Colbert, R.A., Colell, A., Čolić, M., Coll, N.S., Collins, M.O., Colombo, M.I., Colón-Ramos, D.A., Combaret, L., Comincini, S., Cominetti, M.R., Consiglio, A., Conte, A., Conti, F., Contu, V.R., Cookson, M.R., Coombs, K.M., Coppens, I., Corasaniti, M.T., Corkery, D.P., Cordes, N., Cortese, K., Costa, M.D.C., Costantino, S., Costelli, P., Coto-Montes, A., Crack, P.J., Crespo, J.L., Criollo, A., Crippa, V., Cristofani, R., Csizmadia, T., Cuadrado, A., Cui, B., Cui, J., Cui, Y., Cui, Y., Culetto, E., Cumino, A.C., Cybulsky, A.V., Czaja, M.J., Czuczwar, S.J., D'Adamo, S., D'Amelio, M., D'Arcangelo, D., D'Lugos, A.C., D'Orazi, G., da Silva, J.A., Dafsari, H.S., Dagda, R.K., Dagdas, Y., Daglia, M., Dai, X., Dai, Y., Dai, Y., Dal Col, J., Dalhaimer, P., Dalla Valle, L., Dallenga, T., Dalmasso, G., Damme, M., Dando, I., Dantuma, N.P., Darling, A.L., Das, H., Dasarathy, S., Dasari, S.K., Dash, S., Daumke, O., Dauphinee, A.N., Davies, J.S., Dávila, V.A., Davis, R.J., Davis, T., Dayalan Naidu, S., De Amicis, F., De Bosscher, K., De Felice, F., De Franceschi, L., De Leonibus, C., de Mattos Barbosa, M.G., De Meyer, G.R.Y., De Milito, A., De Nunzio, C., De Palma, C., De Santi, M., De Virgilio, C., De Zio, D., Debnath, J., DeBosch, B.J., Decuypere, J.P., Deehan, M.A., Deflorian, G., DeGregori, J., Dehay, B., Del Rio, G., Delaney, J.R., Delbridge, L.M.D., Delorme-Axford, E., Delpino, M.V., Demarchi, F., Dembitz, V., Demers, N.D., Deng, H., Deng, Z., Dengjel, J., Dent, P., Denton, D., DePamphilis, M.L., Der, C.J., Deretic, V., Descoteaux, A., Devis, L., Devkota, S., Devuyst, O., Dewson, G., Dharmasivam, M., Dhiman, R., di Bernardo, D., Di Cristina, M., Di Domenico, F., Di Fazio, P., Di Fonzo, A., Di Guardo, G., Di Guglielmo, G.M., Di Leo, L., Di Malta, C., Di Nardo, A., Di Rienzo, M., Di Sano, F., Diallinas, G., Diao, J., Diaz-Araya, G., Díaz-Laviada, I., Dickinson, J.M., Diederich, M., Dieudé, M., Dikic, I., Ding, S., Ding, W.X., Dini, L., Dinić, J., Dinic, M., Dinkova-Kostova, A.T., Dionne, M.S., Distler, J.H.W., Diwan, A., Dixon, I.M.C., Djavaheri-Mergny, M., Dobrinski, I., Dobrovinskaya, O., Dobrowolski, R., Dobson, R.C.J., Đokić, J., Dokmeci Emre, S., Donadelli, M., Dong, B., Dong, X., Dong, Z., Dorn Ii, G.W., Dotsch, V., Dou, H., Dou, J., Dowaidar, M., Dridi, S., Drucker, L., Du, A., Du, C., Du, G., Du, H.N., Du, L.L., du Toit, A., Duan, S.B., Duan, X., Duarte, S.P., Dubrovska, A., Dunlop, E.A., Dupont, N., Durán, R.V., Dwarakanath, B.S., Dyshlovoy, S.A., Ebrahimi-Fakhari, D., Eckhart, L., Edelstein, C.L., Efferth, T., Eftekharpour, E., Eichinger, L., Eid, N., Eisenberg, T., Eissa, N.T., Eissa, S., Ejarque, M., El Andaloussi, A., El-Hage, N., El-Naggar, S., Eleuteri, A.M., El-Shafey, E.S., Elgendy, M., Eliopoulos, A.G., Elizalde, M.M., Elks, P.M., Elsasser, H.P., Elsherbiny, E.S., Emerling, B.M., Emre, N.C.T., Eng, C.H., Engedal, N., Engelbrecht, A.M., Engelsen, A.S.T., Enserink, J.M., Escalante, R., Esclatine, A., Escobar-Henriques, M., Eskelinen, E.L., Espert, L., Eusebio, M.O., Fabrias, G., Fabrizi, C., Facchiano, A., Facchiano, F., Fadeel, B., Fader, C., Faesen, A.C., Fairlie, W.D., Falcó, A., Falkenburger, B.H., Fan, D., Fan, J., Fan, Y., Fang, E.F., Fang, Y., Fang, Y., Fanto, M., Farfel-Becker, T., Faure, M., Fazeli, G., Fedele, A.O., Feldman, A.M., Feng, D., Feng, J., Feng, L., Feng, Y., Feng, Y., Feng, W., Fenz Araujo, T., Ferguson, T.A., Fernández, A.F., Fernandez-Checa, J.C., Fernández-Veledo, S., Fernie, A.R., Ferrante, A.W., Ferraresi, A., Ferrari, M.F., Ferreira, J.C.B., Ferro-Novick, S., Figueras, A., Filadi, R., Filigheddu, N., Filippi-Chiela, E., Filomeni, G., Fimia, G.M., Fineschi, V., Finetti, F., Finkbeiner, S., Fisher, E.A., Fisher, P.B., Flamigni, F., Fliesler, S.J., Flo, T.H., Florance, I., Florey, O., Florio, T., Fodor, E., Follo, C., Fon, E.A., Forlino, A., Fornai, F., Fortini, P., Fracassi, A., Fraldi, A., Franco, B., Franco, R., Franconi, F., Frankel, L.B., Friedman, S.L., Fröhlich, L.F., Frühbeck, G., Fuentes, J.M., Fujiki, Y., Fujita, N., Fujiwara, Y., Fukuda, M., Fulda, S., Furic, L., Furuya, N., Fusco, C., Gack, M.U., Gaffke, L., Galadari, S., Galasso, A., Galindo, M.F., Gallolu Kankanamalage, S., Galluzzi, L., Galy, V., Gammoh, N., Gan, B., Ganley, I.G., Gao, F., Gao, H., Gao, M., Gao, P., Gao, S.J., Gao, W., Gao, X., Garcera, A., Garcia, M.N., Garcia, V.E., García-Del Portillo, F., Garcia-Escudero, V., Garcia-Garcia, A., Garcia-Macia, M., García-Moreno, D., Garcia-Ruiz, C., García-Sanz, P., Garg, A.D., Gargini, R., Garofalo, T., Garry, R.F., Gassen, N.C., Gatica, D., Ge, L., Ge, W., Geiss-Friedlander, R., Gelfi, C., Genschik, P., Gentle, I.E., Gerbino, V., Gerhardt, C., Germain, K., Germain, M., Gewirtz, D.A., Ghasemipour Afshar, E., Ghavami, S., Ghigo, A., Ghosh, M., Giamas, G., Giampietri, C., Giatromanolaki, A., Gibson, G.E., Gibson, S.B., Ginet, V., Giniger, E., Giorgi, C., Girao, H., Girardin, S.E., Giridharan, M., Giuliano, S., Giulivi, C., Giuriato, S., Giustiniani, J., Gluschko, A., Goder, V., Goginashvili, A., Golab, J., Goldstone, D.C., Golebiewska, A., Gomes, L.R., Gomez, R., Gómez-Sánchez, R., Gomez-Puerto, M.C., Gomez-Sintes, R., Gong, Q., Goni, F.M., González-Gallego, J., Gonzalez-Hernandez, T., Gonzalez-Polo, R.A., Gonzalez-Reyes, J.A., González-Rodríguez, P., Goping, I.S., Gorbatyuk, M.S., Gorbunov, N.V., Görgülü, K., Gorojod, R.M., Gorski, S.M., Goruppi, S., Gotor, C., Gottlieb, R.A., Gozes, I., Gozuacik, D., Graef, M., Gräler, M.H., Granatiero, V., Grasso, D., Gray, J.P., Green, D.R., Greenhough, A., Gregory, S.L., Griffin, E.F., Grinstaff, M.W., Gros, F., Grose, C., Gross, A.S., Gruber, F., Grumati, P., Grune, T., Gu, X., Guan, J.L., Guardia, C.M., Guda, K., Guerra, F., Guerri, C., Guha, P., Guillén, C., Gujar, S., Gukovskaya, A., Gukovsky, I., Gunst, J., Günther, A., Guntur, A.R., Guo, C., Guo, C., Guo, H., Guo, L.W., Guo, M., Gupta, P., Gupta, S.K., Gupta, S., Gupta, V.B., Gupta, V., Gustafsson, A.B., Gutterman, D.D., H B, R., Haapasalo, A., Haber, J.E., Hać, A., Hadano, S., Hafrén, A.J., Haidar, M., Hall, B.S., Halldén, G., Hamacher-Brady, A., Hamann, A., Hamasaki, M., Han, W., Hansen, M., Hanson, P.I., Hao, Z., Harada, M., Harhaji-Trajkovic, L., Hariharan, N., Haroon, N., Harris, J., Hasegawa, T., Hasima Nagoor, N., Haspel, J.A., Haucke, V., Hawkins, W.D., Hay, B.A., Haynes, C.M., Hayrabedyan, S.B., Hays, T.S., He, C., He, Q., He, R.R., He, Y.W., He, Y.Y., Heakal, Y., Heberle, A.M., Hejtmancik, J.F., Helgason, G.V., Henkel, V., Herb, M., Hergovich, A., Herman-Antosiewicz, A., Hernández, A., Hernandez, C., Hernandez-Diaz, S., Hernandez-Gea, V., Herpin, A., Herreros, J., Hervás, J.H., Hesselson, D., Hetz, C., Heussler, V.T., Higuchi, Y., Hilfiker, S., Hill, J.A., Hlavacek, W.S., Ho, E.A., Ho, I.H.T., Ho, P.W.L., Ho, S.L., Ho, W.Y., Hobbs, G.A., Hochstrasser, M., Hoet, P.H.M., Hofius, D., Hofman, P., Höhn, A., Holmberg, C.I., Hombrebueno, J.R., Yi-Ren Hong, C.W.H., Hooper, L.V., Hoppe, T., Horos, R., Hoshida, Y., Hsin, I.L., Hsu, H.Y., Hu, B., Hu, D., Hu, L.F., Hu, M.C., Hu, R., Hu, W., Hu, Y.C., Hu, Z.W., Hua, F., Hua, J., Hua, Y., Huan, C., Huang, C., Huang, C., Huang, C., Huang, C., Huang, H., Huang, K., Huang, M.L.H., Huang, R., Huang, S., Huang, T., Huang, X., Huang, Y.J., Huber, T.B., Hubert, V., Hubner, C.A., Hughes, S.M., Hughes, W.E., Humbert, M., Hummer, G., Hurley, J.H., Hussain, S., Hussain, S., Hussey, P.J., Hutabarat, M., Hwang, H.Y., Hwang, S., Ieni, A., Ikeda, F., Imagawa, Y., Imai, Y., Imbriano, C., Imoto, M., Inman, D.M., Inoki, K., Iovanna, J., Iozzo, R.V., Ippolito, G., Irazoqui, J.E., Iribarren, P., Ishaq, M., Ishikawa, M., Ishimwe, N., Isidoro, C., Ismail, N., Issazadeh-Navikas, S., Itakura, E., Ito, D., Ivankovic, D., Ivanova, S., Iyer, A.K.V., Izquierdo, J.M., Izumi, M., Jäättelä, M., Jabir, M.S., Jackson, W.T., Jacobo-Herrera, N., Jacomin, A.C., Jacquin, E., Jadiya, P., Jaeschke, H., Jagannath, C., Jakobi, A.J., Jakobsson, J., Janji, B., Jansen-Dürr, P., Jansson, P.J., Jantsch, J., Januszewski, S., Jassey, A., Jean, S., Jeltsch-David, H., Jendelova, P., Jenny, A., Jensen, T.E., Jessen, N., Jewell, J.L., Ji, J., Jia, L., Jia, R., Jiang, L., Jiang, Q., Jiang, R., Jiang, T., Jiang, X., Jiang, Y., Jimenez-Sanchez, M., Jin, E.J., Jin, F., Jin, H., Jin, L., Jin, L., Jin, M., Jin, S., Jo, E.K., Joffre, C., Johansen, T., Johnson, G.V.W., Johnston, S.A., Jokitalo, E., Jolly, M.K., Joosten, L.A.B., Jordan, J., Joseph, B., Ju, D., Ju, J.S., Ju, J., Juárez, E., Judith, D., Juhász, G., Jun, Y., Jung, C.H., Jung, S.C., Jung, Y.K., Jungbluth, H., Jungverdorben, J., Just, S., Kaarniranta, K., Kaasik, A., Kabuta, T., Kaganovich, D., Kahana, A., Kain, R., Kajimura, S., Kalamvoki, M., Kalia, M., Kalinowski, D.S., Kaludercic, N., Kalvari, I., Kaminska, J., Kaminskyy, V.O., Kanamori, H., Kanasaki, K., Kang, C., Kang, R., Kang, S.S., Kaniyappan, S., Kanki, T., Kanneganti, T.D., Kanthasamy, A.G., Kanthasamy, A., Kantorow, M., Kapuy, O., Karamouzis, M.V., Karim, M.D.R., Karmakar, P., Katare, R.G., Kato, M., Kaufmann, S.H.E., Kauppinen, A., Kaushal, G.P., Kaushik, S., Kawasaki, K., Kazan, K., Ke, P.Y., Keating, D.J., Keber, U., Kehrl, J.H., Keller, K.E., Keller, C.W., Kemper, J.K., Kenific, C.M., Kepp, O., Kermorgant, S., Kern, A., Ketteler, R., Keulers, T.G., Khalfin, B., Khalil, H., Khambu, B., Khan, S.Y., Khandelwal, V.K.M., Khandia, R., Kho, W., Khobrekar, N.V., Khuansuwan, S., Khundadze, M., Killackey, S.A., Kim, D., Kim, D.R., Kim, D.H., Kim, D.E., Kim, E.Y., Kim, E.K., Kim, H.R., Kim, H.S., Kim, H.R., Kim, J.H., Kim, J.K., Kim, J.H., Kim, J., Kim, J.H., Kim, K.I.I., Kim, P.K., Kim, S.J., Kimball, S.R., Kimchi, A., Kimmelman, A.C., Kimura, T., King, M.A., Kinghorn, K.J., Kinsey, C.G., Kirkin, V., Kirshenbaum, L.A., Kiselev, S.L., Kishi, S., Kitamoto, K., Kitaoka, Y., Kitazato, K., Kitsis, R.N., Kittler, J.T., Kjaerulff, O., Klein, P.S., Klopstock, T., Klucken, J., Knævelsrud, H., Knorr, R.L., Ko, B.C.B., Ko, F., Ko, J.L., Kobayashi, H., Kobayashi, S., Koch, I., Koch, J.C., Koenig, U., Kögel, D., Koh, Y.H., Koike, M., Kohlwein, S.D., Kocaturk, N.M., Komatsu, M., König, J., Kono, T., Kopp, B.T., Korcsmaros, T., Korkmaz, G., Korolchuk, V.I., Korsnes, M.S., Koskela, A., Kota, J., Kotake, Y., Kotler, M.L., Kou, Y., Koukourakis, M.I., Koustas, E., Kovacs, A.L., Kovács, T., Koya, D., Kozako, T., Kraft, C., Krainc, D., Krämer, H., Krasnodembskaya, A.D., Kretz-Remy, C., Kroemer, G., Ktistakis, N.T., Kuchitsu, K., Kuenen, S., Kuerschner, L., Kukar, T., Kumar, A., Kumar, A., Kumar, D., Kumar, D., Kumar, S., Kume, S., Kumsta, C., Kundu, C.N., Kundu, M., Kunnumakkara, A.B., Kurgan, L., Kutateladze, T.G., Kutlu, O., Kwak, S.A., Kwon, H.J., Kwon, T.K., Kwon, Y.T., Kyrmizi, I., La Spada, A., Labonté, P., Ladoire, S., Laface, I., Lafont, F., Lagace, D.C., Lahiri, V., Lai, Z., Laird, A.S., Lakkaraju, A., Lamark, T., Lan, S.H., Landajuela, A., Lane, D.J.R., Lane, J.D., Lang, C.H., Lange, C., Langel, Ü., Langer, R., Lapaquette, P., Laporte, J., LaRusso, N.F., Lastres-Becker, I., Lau, W.C.Y., Laurie, G.W., Lavandero, S., Law, B.Y.K., Law, H.K.W., Layfield, R., Le, W., Le Stunff, H., Leary, A.Y., Lebrun, J.J., Leck, L.Y.W., Leduc-Gaudet, J.P., Lee, C., Lee, C.P., Lee, D.H., Lee, E.B., Lee, E.F., Lee, G.M., Lee, H.J., Lee, H.K., Lee, J.M., Lee, J.S., Lee, J.A., Lee, J.Y., Lee, J.H., Lee, M., Lee, M.G., Lee, M.J., Lee, M.S., Lee, S.Y., Lee, S.J., Lee, S.Y., Lee, S.B., Lee, W.H., Lee, Y.R., Lee, Y.H., Lee, Y., Lefebvre, C., Legouis, R., Lei, Y.L., Lei, Y., Leikin, S., Leitinger, G., Lemus, L., Leng, S., Lenoir, O., Lenz, G., Lenz, H.J., Lenzi, P., León, Y., Leopoldino, A.M., Leschczyk, C., Leskelä, S., Letellier, E., Leung, C.T., Leung, P.S., Leventhal, J.S., Levine, B., Lewis, P.A., Ley, K., Li, B., Li, D.Q., Li, J., Li, J., Li, J., Li, K., Li, L., Li, M., Li, M., Li, M., Li, M., Li, M., Li, P.L., Li, M.Q., Li, Q., Li, S., Li, T., Li, W., Li, W., Li, X., Li, Y.P., Li, Y., Li, Z., Li, Z., Li, Z., Lian, J., Liang, C., Liang, Q., Liang, W., Liang, Y., Liang, Y.T., Liao, G., Liao, L., Liao, M., Liao, Y.F., Librizzi, M., Lie, P.P.Y., Lilly, M.A., Lim, H.J., Lima, T.R.R., Limana, F., Lin, C., Lin, C.W., Lin, D.S., Lin, F.C., Lin, J.D., Lin, K.M., Lin, K.H., Lin, L.T., Lin, P.H., Lin, Q., Lin, S., Lin, S.J., Lin, W., Lin, X., Lin, Y.X., Lin, Y.S., Linden, R., Lindner, P., Ling, S.C., Lingor, P., Linnemann, A.K., Liou, Y.C., Lipinski, M.M., Lipovšek, S., Lira, V.A., Lisiak, N., Liton, P.B., Liu, C., Liu, C.H., Liu, C.F., Liu, C.H., Liu, F., Liu, H., Liu, H.S., Liu, H.F., Liu, H., Liu, J., Liu, J., Liu, J., Liu, L., Liu, L., Liu, M., Liu, Q., Liu, W., Liu, W., Liu, X.H., Liu, X., Liu, X., Liu, X., Liu, X., Liu, Y., Liu, Y., Liu, Y., Liu, Y., Liu, Y., Livingston, J.A., Lizard, G., Lizcano, J.M., Ljubojevic-Holzer, S., LLeonart, M.E., Llobet-Navàs, D., Llorente, A., Lo, C.H., Lobato-Márquez, D., Long, Q., Long, Y.C., Loos, B., Loos, J.A., López, M.G., López-Doménech, G., López-Guerrero, J.A., López-Jiménez, A.T., López-Pérez, O., López-Valero, I., Lorenowicz, M.J., Lorente, M., Lorincz, P., Lossi, L., Lotersztajn, S., Lovat, P.E., Lovell, J.F., Lovy, A., Lőw, P., Lu, G., Lu, H., Lu, J.H., Lu, J.J., Lu, M., Lu, S., Luciani, A., Lucocq, J.M., Ludovico, P., Luftig, M.A., Luhr, M., Luis-Ravelo, D., Lum, J.J., Luna-Dulcey, L., Lund, A.H., Lund, V.K., Lünemann, J.D., Lüningschrör, P., Luo, H., Luo, R., Luo, S., Luo, Z., Luparello, C., Lüscher, B., Luu, L., Lyakhovich, A., Lyamzaev, K.G., Lystad, A.H., Lytvynchuk, L., Ma, A.C., Ma, C., Ma, M., Ma, N.F., Ma, Q.H., Ma, X., Ma, Y., Ma, Z., MacDougald, O.A., Macian, F., MacIntosh, G.C., MacKeigan, J.P., Macleod, K.F., Maday, S., Madeo, F., Madesh, M., Madl, T., Madrigal-Matute, J., Maeda, A., Maejima, Y., Magarinos, M., Mahavadi, P., Maiani, E., Maiese, K., Maiti, P., Maiuri, M.C., Majello, B., Major, M.B., Makareeva, E., Malik, F., Mallilankaraman, K., Malorni, W., Maloyan, A., Mammadova, N., Man, G.C.W., Manai, F., Mancias, J.D., Mandelkow, E.M., Mandell, M.A., Manfredi, A.A., Manjili, M.H., Manjithaya, R., Manque, P., Manshian, B.B., Manzano, R., Manzoni, C., Mao, K., Marchese, C., Marchetti, S., Marconi, A.M., Marcucci, F., Mardente, S., Mareninova, O.A., Margeta, M., Mari, M., Marinelli, S., Marinelli, O., Mariño, G., Mariotto, S., Marshall, R.S., Marten, M.R., Martens, S., Martin, A.P.J., Martin, K.R., Martin, S., Martin, S., Martín-Segura, A., Martín-Acebes, M.A., Martin-Burriel, I., Martin-Rincon, M., Martin-Sanz, P., Martina, J.A., Martinet, W., Martinez, A., Martinez, A., Martinez, J., Martinez Velazquez, M., Martinez-Lopez, N., Martinez-Vicente, M., Martins, D.O., Martins, J.O., Martins, W.K., Martins-Marques, T., Marzetti, E., Masaldan, S., Masclaux-Daubresse, C., Mashek, D.G., Massa, V., Massieu, L., Masson, G.R., Masuelli, L., Masyuk, A.I., Masyuk, T.V., Matarrese, P., Matheu, A., Matoba, S., Matsuzaki, S., Mattar, P., Matte, A., Mattoscio, D., Mauriz, J.L., Mauthe, M., Mauvezin, C., Maverakis, E., Maycotte, P., Mayer, J., Mazzoccoli, G., Mazzoni, C., Mazzulli, J.R., McCarty, N., McDonald, C., McGill, M.R., McKenna, S.L., McLaughlin, B.A., McLoughlin, F., McNiven, M.A., McWilliams, T.G., Mechta-Grigoriou, F., Medeiros, T.C., Medina, D.L., Megeney, L.Y., Megyeri, K., Mehrpour, M., Mehta, J.L., Meijer, A.J., Meijer, A.H., Mejlvang, J., Meléndez, A., Melk, A., Memisoglu, G., Mendes, A.F., Meng, D., Meng, F., Meng, T., Menna-Barreto, R., Menon, M.B., Mercer, C., Mercier, A.E., Mergny, J.L., Merighi, A., Merkley, S.D., Merla, G., Meske, V., Mestre, A.C., Metur, S.P., Meyer, C., Meyer, H., Mi, W., Mialet-Perez, J., Miao, J., Micale, L., Miki, Y., Milan, E., Milczarek, M., Miller, D.L., Miller, S.I., Miller, S., Millward, S.W., Milosevic, I., Minina, E.A., Mirzaei, H., Mirzaei, H.R., Mirzaei, M., Mishra, A., Mishra, N., Mishra, P.K., Misirkic Marjanovic, M., Misasi, R., Misra, A., Misso, G., Mitchell, C., Mitou, G., Miura, T., Miyamoto, S., Miyazaki, M., Miyazaki, M., Miyazaki, T., Miyazawa, K., Mizushima, N., Mogensen, T.H., Mograbi, B., Mohammadinejad, R., Mohamud, Y., Mohanty, A., Mohapatra, S., Möhlmann, T., Mohmmed, A., Moles, A., Moley, K.H., Molinari, M., Mollace, V., Møller, A.B., Mollereau, B., Mollinedo, F., Montagna, C., Monteiro, M.J., Montella, A., Montes, L.R., Montico, B., Mony, V.K., Monzio Compagnoni, G., Moore, M.N., Moosavi, M.A., Mora, A.L., Mora, M., Morales-Alamo, D., Moratalla, R., Moreira, P.I., Morelli, E., Moreno, S., Moreno-Blas, D., Moresi, V., Morga, B., Morgan, A.H., Morin, F., Morishita, H., Moritz, O.L., Moriyama, M., Moriyasu, Y., Morleo, M., Morselli, E., Moruno-Manchon, J.F., Moscat, J., Mostowy, S., Motori, E., Moura, A.F., Moustaid-Moussa, N., Mrakovcic, M., Muciño-Hernández, G., Mukherjee, A., Mukhopadhyay, S., Mulcahy Levy, J.M., Mulero, V., Muller, S., Münch, C., Munjal, A., Munoz-Canoves, P., Muñoz-Galdeano, T., Münz, C., Murakawa, T., Muratori, C., Murphy, B.M., Murphy, J.P., Murthy, A., Myöhänen, T.T., Mysorekar, I.U., Mytych, J., Nabavi, S.M., Nabissi, M., Nagy, P., Nah, J., Nahimana, A., Nakagawa, I., Nakamura, K., Nakatogawa, H., Nandi, S.S., Nanjundan, M., Nanni, M., Napolitano, G., Nardacci, R., Narita, M., Nassif, M., Nathan, I., Natsumeda, M., Naude, R.J., Naumann, C., Naveiras, O., Navid, F., Nawrocki, S.T., Nazarko, T.Y., Nazio, F., Negoita, F., Neill, T., Neisch, A.L., Neri, L.M., Netea, M.G., Neubert, P., Neufeld, T.P., Neumann, D., Neutzner, A., Newton, P.T., Ney, P.A., Nezis, I.P., Ng, C.C.W., Ng, T.B., Nguyen, H.T.T., Nguyen, L.T., Ni, H.M., Ní Cheallaigh, C., Ni, Z., Nicolao, M.C., Nicoli, F., Nieto-Diaz, M., Nilsson, P., Ning, S., Niranjan, R., Nishimune, H., Niso-Santano, M., Nixon, R.A., Nobili, A., Nobrega, C., Noda, T., Nogueira-Recalde, U., Nolan, T.M., Nombela, I., Novak, I., Novoa, B., Nozawa, T., Nukina, N., Nussbaum-Krammer, C., Nylandsted, J., O'Donovan, T.R., O'Leary, S.M., O'Rourke, E.J., O'Sullivan, M.P., O'Sullivan, T.E., Oddo, S., Oehme, I., Ogawa, M., Ogier-Denis, E., Ogmundsdottir, M.H., Ogretmen, B., Oh, G.T., Oh, S.H., Oh, Y.J., Ohama, T., Ohashi, Y., Ohmuraya, M., Oikonomou, V., Ojha, R., Okamoto, K., Okazawa, H., Oku, M., Oliván, S., Oliveira, J.M.A., Ollmann, M., Olzmann, J.A., Omari, S., Omary, M.B., Önal, G., Ondrej, M., Ong, S.B., Ong, S.G., Onnis, A., Orellana, J.A., Orellana-Muñoz, S., Ortega-Villaizan, M.D.M., Ortiz-Gonzalez, X.R., Ortona, E., Osiewacz, H.D., Osman, A.H.K., Osta, R., Otegui, M.S., Otsu, K., Ott, C., Ottobrini, L., Ou, J.H.J., Outeiro, T.F., Oynebraten, I., Ozturk, M., Pagès, G., Pahari, S., Pajares, M., Pajvani, U.B., Pal, R., Paladino, S., Pallet, N., Palmieri, M., Palmisano, G., Palumbo, C., Pampaloni, F., Pan, L., Pan, Q., Pan, W:, Pan, X., Panasyuk, G., Pandey, R., Pandey, U.B., Pandya, V., Paneni, F., Pang, S.Y., Panzarini, E., Papademetrio, D.L., Papaleo, E., Papinski, D., Papp, D., Park, E.C., Park, H.T., Park, J.M., Park, J.I., Park, J.T., Park, J., Park, S.C., Park, S.Y., Parola, A.H., Parys, J.B., Pasquier, A., Pasquier, B., Passos, J.F., Pastore, N., Patel, H.H., Patschan, D., Pattingre, S., Pedraza-Alva, G., Pedraza-Chaverri, J., Pedrozo, Z., Pei, G., Pei, J., Peled-Zehavi, H., Pellegrini, J.M., Pelletier, J., Peñalva, M.A., Peng, D., Peng, Y., Penna, F., Pennuto, M., Pentimalli, F., Pereira, C.M.F., Pereira, G.J.S., Pereira, L.C., Pereira de Almeida, L., Perera, N.D., Pérez-Lara, A., Perez-Oliva, A.B., Pérez-Pérez, M.E., Periyasamy, P., Perl, A., Perrotta, C., Perrotta, I., Pestell, R.G., Petersen, M., Petrache, I., Petrovski, G., Pfirrmann, T., Pfister, A.S., Philips, J.A., Pi, H., Picca, A., Pickrell, A.M., Picot, S., Pierantoni, G.M., Pierdominici, M., Pierre, P., Pierrefite-Carle, V., Pierzynowska, K., Pietrocola, F., Pietruczuk, M., Pignata, C., Pimentel-Muiños, F.X., Pinar, M., Pinheiro, R.O., Pinkas-Kramarski, R., Pinton, P., Pircs, K., Piya, S., Pizzo, P., Plantinga, T.S., Platta, H.W., Plaza-Zabala, A., Plomann, M., Plotnikov, E.Y., Plun-Favreau, H., Pluta, R., Pocock, R., Pöggeler, S., Pohl, C., Poirot, M., Poletti, A., Ponpuak, M., Popelka, H., Popova, B., Porta, H., Porte Alcon, S., Portilla-Fernandez, E., Post, M., Potts, M.B., Poulton, J., Powers, T., Prahlad, V., Prajsnar, T.K., Praticò, D., Prencipe, R., Priault, M., Proikas-Cezanne, T., Promponas, V.J., Proud, C.G., Puertollano, R., Puglielli, L., Pulinilkunnil, T., Puri, D., Puri, R., Puyal, J., Qi, X., Qi, Y., Qian, W., Qiang, L., Qiu, Y., Quadrilatero, J., Quarleri, J., Raben, N., Rabinowich, H., Ragona, D., Ragusa, M.J., Rahimi, N., Rahmati, M., Raia, V., Raimundo, N., Rajasekaran, N.S., Ramachandra Rao, S., Rami, A., Ramírez-Pardo, I., Ramsden, D.B., Randow, F., Rangarajan, P.N., Ranieri, D., Rao, H., Rao, L., Rao, R., Rathore, S., Ratnayaka, J.A., Ratovitski, E.A., Ravanan, P., Ravegnini, G., Ray, S.K., Razani, B., Rebecca, V., Reggiori, F., Régnier-Vigouroux, A., Reichert, A.S., Reigada, D., Reiling, J.H., Rein, T., Reipert, S., Rekha, R.S., Ren, H., Ren, J., Ren, W., Renault, T., Renga, G., Reue, K., Rewitz, K., Ribeiro de Andrade Ramos, B., Riazuddin, S.A., Ribeiro-Rodrigues, T.M., Ricci, J.E., Ricci, R., Riccio, V., Richardson, D.R., Rikihisa, Y., Risbud, M.V., Risueño, R.M., Ritis, K., Rizza, S., Rizzuto, R., Roberts, H.C., Roberts, L.D., Robinson, K.J., Roccheri, M.C., Rocchi, S., Rodney, G.G., Rodrigues, T., Rodrigues Silva, V.R., Rodriguez, A., Rodriguez-Barrueco, R., Rodriguez-Henche, N., Rodriguez-Rocha, H., Roelofs, J., Rogers, R.S., Rogov, V.V., Rojo, A.I., Rolka, K., Romanello, V., Romani, L., Romano, A., Romano, P.S., Romeo-Guitart, D., Romero, L.C., Romero, M., Roney, J.C., Rongo, C., Roperto, S., Rosenfeldt, M.T., Rosenstiel, P., Rosenwald, A.G., Roth, K.A., Roth, L., Roth, S., Rouschop, K.M.A., Roussel, B.D., Roux, S., Rovere-Querini, P., Roy, A., Rozieres, A., Ruano, D., Rubinsztein, D.C., Rubtsova, M.P., Ruckdeschel, K., Ruckenstuhl, C., Rudolf, E., Rudolf, R., Ruggieri, A., Ruparelia, A.A., Rusmini, P., Russell, R.R., Russo, G.L., Russo, M., Russo, R., Ryabaya, O.O., Ryan, K.M., Ryu, K.Y., Sabater-Arcis, M., Sachdev, U., Sacher, M., Sachse, C., Sadhu, A., Sadoshima, J., Safren, N., Saftig, P., Sagona, A.P., Sahay, G., Sahebkar, A., Sahin, M., Sahin, O., Sahni, S., Saito, N., Saito, S., Saito, T., Sakai, R., Sakai, Y., Sakamaki, J.I., Saksela, K., Salazar, G., Salazar-Degracia, A., Salekdeh, G.H., Saluja, A.K., Sampaio-Marques, B., Sanchez, M.C., Sanchez-Alcazar, J.A., Sanchez-Vera, V., Sancho-Shimizu, V., Sanderson, J.T., Sandri, M., Santaguida, S., Santambrogio, L., Santana, M.M., Santoni, G., Sanz, A., Sanz, P., Saran, S., Sardiello, M., Sargeant, T.J., Sarin, A., Sarkar, C., Sarkar, S., Sarrias, M.R., Sarkar, S., Sarmah, D.T., Sarparanta, J., Sathyanarayan, A., Sathyanarayanan, R., Scaglione, K.M., Scatozza, F., Schaefer, L., Schafer, Z.T., Schaible, U.E., Schapira, A.H.V., Scharl, M., Schatzl, H.M., Schein, C.H., Scheper, W., Scheuring, D., Schiaffino, M.V., Schiappacassi, M., Schindl, R., Schlattner, U., Schmidt, O., Schmitt, R., Schmidt, S.D., Schmitz, I., Schmukler, E., Schneider, A., Schneider, B.E., Schober, R., Schoijet, A.C., Schott, M.B., Schramm, M., Schröder, B., Schuh, K., Schüller, C., Schulze, R.L., Schürmanns, L., Schwamborn, J.C., Schwarten, M., Scialo, F., Sciarretta, S., Scott, M.J., Scotto, K.W., Scovassi, A.I., Scrima, A., Scrivo, A., Sebastian, D., Sebti, S., Sedej, S., Segatori, L., Segev, N., Seglen, P.O., Seiliez, I., Seki, E., Selleck, S.B., Sellke, F.W., Selsby, J.T., Sendtner, M., Senturk, S., Seranova, E., Sergi, C., Serra-Moreno, R., Sesaki, H., Settembre, C., Setty, S.R.G., Sgarbi, G., Sha, O., Shacka, J.J., Shah, J.A., Shang, D., Shao, C., Shao, F., Sharbati, S., Sharkey, L.M., Sharma, D., Sharma, G., Sharma, K., Sharma, P., Sharma, S., Shen, H.M., Shen, H., Shen, J., Shen, M., Shen, W., Shen, Z., Sheng, R., Sheng, Z., Sheng, Z.H., Shi, J., Shi, X., Shi, Y.H., Shiba-Fukushima, K., Shieh, J.J., Shimada, Y., Shimizu, S., Shimozawa, M., Shintani, T., Shoemaker, C.J., Shojaei, S., Shoji, I., Shravage, B.V., Shridhar, V., Shu, C.W., Shu, H.B., Shui, K., Shukla, A.K., Shutt, T.E., Sica, V., Siddiqui, A., Sierra, A., Sierra-Torre, V., Signorelli, S., Sil, P., Silva, B.J.A., Silva, J.D., Silva-Pavez, E., Silvente-Poirot, S., Simmonds, R.E., Simon, A.K., Simon, H.U., Simons, M., Singh, A., Singh, L.P., Singh, R., Singh, S.V., Singh, S.K., Singh, S.B., Singh, S., Singh, S.P., Sinha, D., Sinha, R.A., Sinha, S., Sirko, A., Sirohi, K., Sivridis, E.L., Skendros, P., Skirycz, A., Slaninová, I., Smaili, S.S., Smertenko, A., Smith, M.D., Soenen, S.J., Sohn, E.J., Sok, S.P.M., Solaini, G., Soldati, T., Soleimanpour, S.A., Soler, R.M., Solovchenko, A., Somarelli, J.A., Sonawane, A., Song, F., Song, H.K., Song, J.X., Song, K., Song, Z., Soria, L.R., Sorice, M., Soukas, A.A., Soukup, S.F., Sousa, D., Sousa, N., Spagnuolo, P.A., Spector, S.A., Srinivas Bharath, M.M., St Clair, D., Stagni, V., Staiano, L., Stalnecker, C.A., Stankov, M.V., Stathopulos, P.B., Stefan, K., Stefan, S.M., Stefanis, L., Steffan, J.S., Steinkasserer, A., Stenmark, H., Sterneckert, J., Stevens, C., Stoka, V., Storch, S., Stork, B., Strappazzon, F., Strohecker, A.M., Stupack, D.G., Su, H., Su, L.Yy, Su, L., Suarez-Fontes, A.M., Subauste, C.S., Subbian, S., Subirada, P.V., Sudhandiran, G., Sue, C.M., Sui, X., Summers, C., Sun, G., Sun, J., Sun, K., Sun, M.X., Sun, Q., Sun, Y., Sun, Z., Sunahara, K.K.S., Sundberg, E., Susztak, K., Sutovsky, P., Suzuki, H., Sweeney, G., Symons, J.D., Sze, S.C.W., Szewczyk, N.J., Tabęcka-Łonczynska, A., Tabolacci, C., Tacke, F., Taegtmeyer, H., Tafani, M., Tagaya, M., Tai, H., Tait, S.W.G., Takahashi, Y., Takats, S., Talwar, P., Tam, C., Tam, S.Y., Tampellini, D., Tamura, A., Tan, C.T., Tan, E.K., Tan, Y.Q., Tanaka, M., Tanaka, M., Tang, D., Tang, J., Tang, T.S., Tanida, I., Tao, Z., Taouis, M., Tatenhorst, L., Tavernarakis, N., Taylor, A., Taylor, G.A., Taylor, J.M., Tchetina, E., Tee, A.R., Tegeder, I., Teis, D., Teixeira, N., Teixeira-Clerc, F., Tekirdag, K.A., Tencomnao, T., Tenreiro, S., Tepikin, A.V., Testillano, P.S., Tettamanti, G., Tharaux, P.L., Thedieck, K., Thekkinghat, A.A., Thellung, S., Thinwa, J.W., Thirumalaikumar, V.P., Thomas, S.M., Thomes, P.G., Thorburn, A., Thukral, L., Thum, T., Thumm, M., Tian, L., Tichy, A., Till, A., Timmerman, V., Titorenko, V.I., Todi, S.V., Todorova, K., Toivonen, J.M., Tomaipitinca, L., Tomar, D., Tomas-Zapico, C., Tomić, S., Tong, B.C.K., Tong, C., Tong, X., Tooze, S.A., Torgersen, M.L., Torii, S., Torres-López, L., Torriglia, A., Towers, C.G., Towns, R., Toyokuni, S., Trajkovic, V., Tramontano, D., Tran, Q.G., Travassos, L.H., Trelford, C.B., Tremel, S., Trougakos, I.P., Tsao, B.P., Tschan, M.P., Tse, H.F., Tse, T.F., Tsugawa, H., Tsvetkov, A.S., Tumbarello, D.A., Tumtas, Y., Tuñón, M.J., Turcotte, S., Turk, B., Turk, V., Turner, B.J., Tuxworth, R.I., Tyler, J.K., Tyutereva, E.V., Uchiyama, Y., Ugun-Klusek, A., Uhlig, H.H., Ułamek-Kozioł, M., Ulasov, I.V., Umekawa, M., Ungermann, C., Unno, R., Urbe, S., Uribe-Carretero, E., Üstün, S., Uversky, V.N., Vaccari, T., Vaccaro, M.I., Vahsen, B.F., Vakifahmetoglu-Norberg, H., Valdor, R., Valente, M.J., Valko, A., Vallee, R.B., Valverde, A.M., Van den Berghe, G., van der Veen, S., Van Kaer, L., van Loosdregt, J., van Wijk, S.J.L., Vandenberghe, W., Vanhorebeek, I., Vannier-Santos, M.A., Vannini, N., Vanrell, M.C., Vantaggiato, C., Varano, G., Varela-Nieto, I., Varga, M., Vasconcelos, M.H., Vats, S., Vavvas, D.G., Vega-Naredo, I., Vega-Rubin-de-Celis, S., Velasco, G., Velázquez, A.P., Vellai, T., Vellenga, E., Velotti, F., Verdier, M., Verginis, P., Vergne, I., Verkade, P., Verma, M., Verstreken, P., Vervliet, T., Vervoorts, J., Vessoni, A.T., Victor, V.M., Vidal, M., Vidoni, C., Vieira, O.V., Vierstra, R.D., Viganó, S., Vihinen, H., Vijayan, V., Vila, M., Vilar, M., Villalba, J.M., Villalobo, A., Villarejo-Zori, B., Villarroya, F., Villarroya, J., Vincent, O., Vindis, C., Viret, C., Viscomi, M.T., Visnjic, D., Vitale, I., Vocadlo, D.J., Voitsekhovskaja, O.V., Volonté, C., Volta, M., Vomero, M., Von Haefen, C., Vooijs, M.A., Voos, W., Vucicevic, L., Wade-Martins, R., Waguri, S., Waite, K.A., Wakatsuki, S., Walker, D.W., Walker, M.J., Walker, S.A., Walter, J., Wandosell, F.G., Wang, B., Wang, C.Y., Wang, C., Wang, C., Wang, C., Wang, C.Y., Wang, D., Wang, F., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H., Wang, H., Wang, H.G., Wang, J., Wang, J., Wang, J., Wang, J., Wang, K., Wang, L., Wang, L., Wang, M.H., Wang, M., Wang, N., Wang, P., Wang, P., Wang, P., Wang, P., Wang, Q.J., Wang, Q., Wang, Q.K., Wang, Q.A., Wang, W.T., Wang, W., Wang, X., Wang, X., Wang, Y., Wang, Y., Wang, Y., Wang, Y.Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Z., Wang, Z., Wang, Z., Warnes, G., Warnsmann, V., Watada, H., Watanabe, E., Watchon, M., Wawrzyńska, A., Weaver, T.E., Wegrzyn, G., Wehman, A.M., Wei, H., Wei, L., Wei, T., Wei, Y., Weiergräber, O.H., Weihl, C.C., Weindl, G., Weiskirchen, R., Wells, A., Wen, R.H., Wen, X., Werner, A., Weykopf, B., Wheatley, S.P., Whitton, J.L., Whitworth, A.J., Wiktorska, K., Wildenberg, M.E., Wileman, T., Wilkinson, S., Willbold, D., Williams, B., Williams, R.S.B., Williams, R.L., Williamson, P.R., Wilson, R.A., Winner, B., Winsor, N.J., Witkin, S.S., Wodrich, H., Woehlbier, U., Wollert, T., Wong, E., Wong, J.H., Wong, R.W., Wong, V.K.W., Wong, W.L., Wu, A.G., Wu, C., Wu, J., Wu, J., Wu, K.K., Wu, M., Wu, S.Y., Wu, S., Wu, S.Y., Wu, S., Wu, W.K.K., Wu, X., Wu, X., Wu, Y.W., Wu, Y., Xavier, R.J., Xia, H., Xia, L., Xia, Z., Xiang, G., Xiang, J., Xiang, M., Xiang, W., Xiao, B., Xiao, G., Xiao, H., Xiao, H.T., Xiao, J., Xiao, L., Xiao, S., Xiao, Y., Xie, B., Xie, C.M., Xie, M., Xie, Y., Xie, Z., Xie, Z., Xilouri, M., Xu, C., Xu, E., Xu, H., Xu, J., Xu, J.R., Xu, L., Xu, W.W., Xu, X., Xue, Y., Yakhine-Diop, S.M.S., Yamaguchi, M., Yamaguchi, O., Yamamoto, A., Yamashina, S., Yan, S., Yan, S.J., Yan, Z., Yanagi, Y., Yang, C., Yang, D.S., Yang, H., Yang, H.T., Yang, H., Yang, J.M., Yang, J., Yang, J., Yang, L., Yang, L., Yang, M., Yang, P.M., Yang, Q., Yang, S., Yang, S., Yang, S.F., Yang, W., Yang, W.Y., Yang, X., Yang, X., Yang, Y., Yang, Y., Yao, H., Yao, S., Yao, X., Yao, Y.G., Yao, Y.M., Yasui, T., Yazdankhah, M., Yen, P.M., Yi, C., Yin, X.M., Yin, Y., Yin, Z., Yin, Z., Ying, M., Ying, Z., Yip, C.K., Yiu, S.P.T., Yoo, Y.H., Yoshida, K., Yoshii, S.R., Yoshimori, T., Yousefi, B., Yu, B., Yu, H., Yu, J., Yu, J., Yu, L., Yu, M.L., Yu, S.W., Yu, V.C., Yu, W.H., Yu, Z., Yu, Z., Yuan, J., Yuan, L.Q., Yuan, S., Yuan, S.S.F., Yuan, Y., Yuan, Z., Yue, J., Yue, Z., Yun, J., Yung, R.L., Zacks, D.N., Zaffagnini, G., Zambelli, V.O., Zanella, I., Zang, Q.S., Zanivan, S., Zappavigna, S., Zaragoza, P., Zarbalis, K.S., Zarebkohan, A., Zarrouk, A., Zeitlin, S.O., Zeng, J., Zeng, J.D., Žerovnik, E., Zhan, L., Zhang, B., Zhang, D.D., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H.L., Zhang, J., Zhang, J., Zhang, J.P., Zhang, K.Y.B., Zhang, L.W., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, M., Zhang, P., Zhang, S., Zhang, W., Zhang, X., Zhang, X.W., Zhang, X., Zhang, X., Zhang, X., Zhang, X., Zhang, X.D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y.D., Zhang, Y., Zhang, Y.Y., Zhang, Y., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhao, H., Zhao, L., Zhao, S., Zhao, T., Zhao, X.F., Zhao, Y., Zhao, Y., Zhao, Y., Zhao, Y., Zheng, G., Zheng, K., Zheng, L., Zheng, S., Zheng, X.L., Zheng, Y., Zheng, Z.G., Zhivotovsky, B., Zhong, Q., Zhou, A., Zhou, B., Zhou, C., Zhou, G., Zhou, H., Zhou, H., Zhou, H., Zhou, J., Zhou, J., Zhou, J., Zhou, J., Zhou, K., Zhou, R., Zhou, X.J., Zhou, Y., Zhou, Y., Zhou, Y., Zhou, Z.Y., Zhou, Z., Zhu, B., Zhu, C., Zhu, G.Q., Zhu, H., Zhu, H., Zhu, H., Zhu, W.G., Zhu, Y., Zhu, Y., Zhuang, H., Zhuang, X., Zientara-Rytter, K., Zimmermann, C.M., Ziviani, E., Zoladek, T., Zong, W.X., Zorov, D.B., Zorzano, A., Zou, W., Zou, Z., Zou, Z., Zuryn, S., Zwerschke, W., Brand-Saberi, B., Dong, X.C., Kenchappa, C.S., Li, Z., Lin, Y., Oshima, S., Rong, Y., Sluimer, J.C., Stallings, C.L. and Tong, C.K.
Autophagy 17
(1): 1-382.
8 February 2021
TET proteins and 5-methylcytosine oxidation in hematological cancers.
Ko, M., An, J., Pastor, W.A., Koralov, S.B., Rajewsky, K. and Rao, A.
Immunological Reviews 263
(1): 6-21.
January 2015
Small ones to fight a big problem-intervention of cancer metastasis by small molecules.
Kobelt, D., Dahlmann, M., Dumbani, M., Güllü, N., Kortüm, B., Vílchez, M.E.A., Stein, U. and Walther, W.
Cancers 12
(6): 1454.
3 June 2020
XDSAPP: a graphical user interface for the convenient processing of diffraction data using XDS.
Krug, M., Weiss, M.S., Heinemann, U. and Mueller, U.
Journal of Applied Crystallography 45
(3): 568-572.
June 2012
Tomo-seq: A method to obtain genome-wide expression data with spatial resolution.
Kruse, F., Junker, J.P., van Oudenaarden, A. and Bakkers, J.
Methods in Cell Biology 135
: 299-307.
2016
Computational approaches to discovering noncoding RNA.
Krzyzanowski, P.M., Muro, E.M. and Andrade-Navarro, M.A.
Wiley Interdisciplinary Reviews: RNA 3
(4): 567-579.
July 2012
Limiting factors in single particle cryo electron tomography.
Kudryashev, M., Castaño-Díez, D. and Stahlberg, H.
Computational and Structural Biotechnology Journal 1
(2): e201207002.
July 2012
Diversity in structure and function of tethering complexes: Evidence for different mechanisms in vesicular transport regulation.
Kuemmel, D. and Heinemann, U.
Current Protein & Peptide Science 9
(2): 197-209.
April 2008
T cell receptors for clinical therapy: in vitro assessment of toxicity risk.
Kunert, A., Obenaus, M., Lamers, C.H.J., Blankenstein, T. and Debets, R.
Clinical Cancer Research 23
(20): 6012-6020.
15 October 2017
Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury.
Kusch, A., Hoff, U., Bubalo, G., Zhu, Y., Fechner, M., Schmidt-Ullrich, R., Marko, L., Müller, D.N., Schmidt-Ott, K.M., Gürgen, D., Blum, M., Schunck, W.H. and Dragun, D.
Acta Physiologica 208
(1): 25-40.
May 2013
How cell death shapes cancer.
Labi, V. and Erlacher, M.
Cell Death & Disease 6
: e1675.
5 March 2015
Divergent transcription and epigenetic directionality of human promoters.
Lacadie, S.A., Ibrahim, M.M., Gokhale, S.A. and Ohler, U.
FEBS Journal 283
(23): 4214-4222.
December 2016
An oscillatory network controlling self-renewal of skeletal muscle stem cells.
Lahmann, I., Zhang, Y., Baum, K., Wolf, J. and Birchmeier, C.
Experimental Cell Research 409
(2): 112933.
15 December 2021
On the importance of cotranscriptional RNA structure formation.
Lai, D., Proctor, J.R. and Meyer, I.M.
RNA 19
(11): 1461-1473.
November 2013
Mechanisms of resistance to small molecules in acute myeloid leukemia.
Lang, T.J.L., Damm, F., Bullinger, L. and Frick, M.
Cancers 15
(18): 4573.
15 September 2023
Stomatin-domain proteins.
Lapatsina, L., Brand, J., Poole, K., Daumke, O. and Lewin, G.R.
European Journal of Cell Biology 91
(4): 240-245.
April 2012
TAP-independent antigen presentation on MHC class I molecules: lessons from Epstein-Barr virus.
Lautscham, G., Rickinson, A. and Blake, N.
Microbes and Infection 5
(4): 291-299.
April 2003
Diversification of antibodies: from V(D)J recombination to somatic exon shuffling.
Lebedin, M. and de la Rosa, K.
Annual Review of Cell and Developmental Biology 40
(1): 265-281.
October 2024
Chemotherapy response and resistance.
Lee, S. and Schmitt, C.A.
Current Opinion in Genetics & Development 13
(1): 90-96.
February 2003
The Myc/macrophage tango: Oncogene-induced senescence, Myc style.
Lee, S., Schmitt, C.A. and Reimann, M.
Seminars in Cancer Biology 21
(6): 377-384.
December 2011
The dynamic nature of senescence in cancer.
Lee, S. and Schmitt, C.A.
Nature Cell Biology 21
(1): 94-101.
January 2019
Subtomogram averaging from cryo-electron tomograms.
Leigh, K.E., Navarro, P.P., Scaramuzza, S., Chen, W., Zhang, Y., Castaño-Díez, D. and Kudryashev, M.
Methods in Cell Biology 152
: 217-259.
2019
Neuroblastoma imaging.
Ley, S., Ley-Zaporozhan, J., Günther, P., Deubzer, H.E., Witt, O. and Schenk, J.P.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 183
(3): 217-225.
March 2011
Pathophysiological role of caveolae in hypertension.
Lian, X., Matthaeus, C., Kaßmann, M., Daumke, O. and Gollasch, M.
Frontiers in Medicine 6
: 153.
July 2019
The role of biologics in stomach cancer.
Lordick, F., Schulze, T. and Jaeger, D.
Targeted Oncology 3
(2): 71-79.
April 2008
Emerging cellular and gene therapies for congenital anemias.
Ludwig, L.S., Khajuria, R.K. and Sankaran, V.G.
American Journal of Medical Genetics C 172C
(4): 332-348.
12 December 2016
Breaking TADs: how alterations of chromatin domains result in disease.
Lupiáñez, D.G., Spielmann, M. and Mundlos, S.
Trends in Genetics 32
(4): 225-237.
April 2016
Tumorprofiling durch Microarray-Technologie [Tumor-profiling by microarray technology].
Lustig, B., Morkel, M. and Schlag, P.M.
Onkologe 7
(10): 1111-1119.
October 2001
Cardiovascular medications in angiogenesis- how to avoid the sting in the tail.
Ma, C., Wang, Q., Man, Y. and Kemmner, W.
International Journal of Cancer 131
(6): 1249-1259.
15 September 2012
Infectious complications of targeted drugs and biotherapies in acute leukemia. Clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL), a joint venture of the European Group for Blood and Marrow Transplantation (EBMT), the European Organization for Research and Treatment of Cancer (EORTC), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN).
Maschmeyer, G., Bullinger, L., Garcia-Vidal, C., Herbrecht, R., Maertens, J., Menna, P., Pagano, L., Thiebaut-Bertrand, A. and Calandra, T.
Leukemia 36
(5): 1215-1226.
May 2022
Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives.
Mates, L., Izsvak, Z. and Ivics, Z.
Genome Biology 8 Suppl 1
: S1.
31 October 2007
The pathogenesis of classical Hodgkin's lymphoma: a model for B-cell plasticity.
Mathas, S.
Hematology Oncology Clinics of North America 21
(5): 787-804.
October 2007
Die molekulare Pathogenese des klassischen Hodgkin-Lymphoms [The molecular pathogenesis of classical Hodgkin lymphoma].
Mathas, S., Doerken, B. and Janz, M.
Deutsche Medizinische Wochenschrift 134
(39): 1944-1948.
September 2009
Mechanisms of Lin28-mediated miRNA and mRNA regulation : a structural and functional perspective.
Mayr, F. and Heinemann, U.
International Journal of Molecular Sciences 14
(8): 16532-16553.
9 August 2013
Physiological functions of intracellular protein degradation.
McShane, E. and Selbach, M.
Annual Review of Cell and Developmental Biology 38
: 241-262.
October 2022
ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum.
Mehnert, M., Sommer, T. and Jarosch, E.
BioEssays 32
(10): 905-913.
October 2010
Angiogenesis in lymph nodes is a critical regulator of immune response and lymphoma growth.
Menzel, L., Höpken, U.E. and Rehm, A.
Frontiers in Immunology 11
: 591741.
3 December 2020
Degrons in cancer.
Meszaros, B., Kumar, M., Gibson, T.J., Uyar, B. and Dosztanyi, Z.
Science Signaling 10
(470): eaak9982.
14 March 2017
Synthetic embryology: controlling geometry to model early mammalian development.
Metzger, J.J., Simunovic, M. and Brivanlou, A.H.
Current Opinion in Genetics & Development 52
: 86-91.
October 2018
ERAD: the long road to destruction.
Meusser, B., Hirsch, C., Jarosch, E. and Sommer, T.
Nature Cell Biology 7
(8): 766-772.
August 2005
Predicting novel RNA-RNA interactions.
Meyer, I.M.
Current Opinion in Structural Biology 18
(3): 387-393.
June 2008
A practical guide to the art of RNA gene prediction.
Meyer, I.M.
Briefings in Bioinformatics 8
(6): 396-414.
November 2007
Peptide-based interaction proteomics.
Meyer, K. and Selbach, M.
Molecular & Cellular Proteomics 19
(7): 1070-1075.
July 2020
The Senescence-Stemness Alliance - a cancer-hijacked regeneration principle.
Milanovic, M., Yu, Y. and Schmitt, C.A.
Trends in Cell Biology 28
(12): 1049-1061.
December 2018
DNA transposons in vertebrate functional genomics.
Miskey, C., Izsvak, Z., Kawakami, K. and Ivics, Z.
Cellular and Molecular Life Sciences 62
(6): 629-641.
March 2005
Sodium as an important regulator of immunometabolism.
Miyauchi, H., Geisberger, S., Luft, F.C., Wilck, N., Stegbauer, J., Wiig, H., Dechend, R., Jantsch, J., Kleinewietfeld, M., Kempa, S. and Mueller, D.N.
Hypertension 81
(3): 426-435.
March 2024
Transcriptional control of macrophage identity, self-renewal, and function.
Molawi, K. and Sieweke, M.H.
Advances in Immunology 120
: 269-300.
2013
Toward identification of functional sequences and variants in noncoding DNA.
Monti, R. and Ohler, U.
Annual Review of Biomedical Data Science 6
: 191-210.
August 2023
Accelerating drug development for neuroblastoma: summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma.
Moreno, L., Barone, G., DuBois, S.G., Molenaar, J., Fischer, M., Schulte, J., Eggert, A., Schleiermacher, G., Speleman, F., Chesler, L., Geoerger, B., Hogarty, M.D., Irwin, M.S., Bird, N., Blanchard, G.B., Buckland, S., Caron, H., Davis, S., De Wilde, B., Deubzer, H.E., Dolman, E., Eilers, M., George, R.E., George, S., Jaroslav, Š., Maris, J.M., Marshall, L., Merchant, M., Mortimer, P., Owens, C., Philpott, A., Poon, E., Shay, J.W., Tonelli, R., Valteau-Couanet, D., Vassal, G., Park, J.R. and Pearson, A.D.J.
European Journal of Cancer 136
: 52-68.
September 2020
Single-cell genomics to study developmental cell fate decisions in zebrafish.
Moreno-Ayala, R. and Junker, J.P.
Briefings in Functional Genomics 20
(6): 420–426.
November 2021
A (3D-nuclear) space odyssey: making sense of Hi-C maps.
Mota-Gómez, I. and Lupiáñez, D.G.
Genes 10
(6): 415.
29 May 2019
Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets.
Mudduluru, G., Walther, W., Kobelt, D., Dahlmann, M., Treese, C., Assaraf, Y.G. and Stein, U.
Drug Resistance Updates 26
: 10-27.
May 2016
Concerted action of the chemokine and lymphotoxin system in secondary lymphoid-organ development.
Mueller, G. and Lipp, M.
Current Opinion in Immunology 15
(2): 217-224.
April 2003
Mn2+-DNA interactions in aqueous systems: A Raman spectroscopic study.
Muntean, C.M., Misselwitz, R., Dostal, L. and Welfle, H.
Spectroscopy 20
(1): 29-35.
January 2006
Functional evidence of post-transcriptional regulation by pseudogenes.
Muro, E.M., Mah, N. and Andrade-Navarro, M.A.
Biochimie 93
(11): 1916-1921.
November 2011
The impact of CCR7 and CXCR5 on lymphoid organ development and systemic immunity.
Müller, G., Höpken, U.E. and Lipp, M.
Immunological Reviews 195
(1): 117-135.
October 2003
Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: an update.
Nakamura, M., Schneider, M.R., Schmidt-Ullrich, R. and Paus, R.
Journal of Dermatological Science 69
(1): 6-29.
January 2013
Evolutionary molecular medicine.
Nesse, R.M., Ganten, D., Gregory, T.R. and Omenn, G.S.
Journal of Molecular Medicine 90
(5): 509-522.
May 2012
Reconstitution of mammary gland development in vitro: Requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.
Niemann, C., Brinkmann, V., Spitzer, E., Hartmann, G., Sachs, M., Naundorf, H. and Birchmeier, W.
Journal of Cell Biology 143
(2): 533-545.
19 October 1998
SHP-2 in lymphocytes' cytokine and inhibitory receptor signaling.
Niogret, C., Birchmeier, W. and Guarda, G.
Frontiers in Immunology 10
: 2468.
25 October 2019
Mitochondrial genetics through the lens of single-cell multi-omics.
Nitsch, L., Lareau, C.A. and Ludwig, L.S.
Nature Genetics 56
(7): 1355-1365.
July 2024
Sequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamics.
Noel, J.K., Morcos, F. and Onuchic, J.N.
F1000 Research 5
(F1000 Faculty Rev): 106.
26 January 2016
Pathogenesis of non-Hodgkin's lymphoma.
Nogai, H., Doerken, B. and Lenz, G.
Journal of Clinical Oncology 29
(14): 1803-1811.
10 May 2011
Targeting of HDAC8 and investigational inhibitors in neuroblastoma.
Oehme, I., Deubzer, H.E., Lodrini, M., Milde, T. and Witt, O.
Expert Opinion on Investigational Drugs 18
(11): 1605-1617.
November 2009
Promoting developmental transcription.
Ohler, U. and Wassarman, D.A.
Development 137
(1): 15-26.
January 2010
New trends in pharmacogenomic strategies against resistance development in microbial infections.
Ohlsen, K., Dandekar, G., Schwarz, R. and Dandekar, T.
Pharmacogenomics 9
(11): 1711-1723.
November 2008
Improving the transport of chemotherapeutic drugs across the blood-brain barrier.
Orthmann, A., Fichtner, I. and Zeisig, R.
Expert Review of Clinical Pharmacology 4
(4): 477-490.
July 2011
Underlying mechanisms for distant metastasis - molecular biology.
Pachmayr, E., Treese, C. and Stein, U.
Visceral Medicine 33
(1): 11-20.
February 2017
Vectors and strategies for nonviral cancer gene therapy.
Pahle, J. and Walther, W.
Expert Opinion on Biological Therapy 16
(4): 443-461.
April 2016
A reference guide for tree analysis and visualization.
Pavlopoulos, G.A., Soldatos, T.G., Barbosa-Silva, A. and Schneider, R.
BioData Mining 3
: 1.
22 February 2010
Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
Pearson, A.D.J., Federico, S., Gatz, S.A., Ortiz, M., Lesa, G., Scobie, N., Gounaris, I., Weiner, S.L., Weigel, B., Unger, T.J., Stewart, E., Smith, M., Slotkin, E.K., Reaman, G., Pappo, A., Nysom, K., Norga, K., McDonough, J., Marshall, L.V., Ludwinski, D., Ligas, F., Karres, D., Kool, M., Horner, T.J., Henssen, A., Heenen, D., Hawkins, D.S., Gore, L., Bender, J.G., Galluzzo, S., Fox, E., de Rojas, T., Davies, B.R., Chakrabarti, J., Carmichael, J., Bradford, D., Blanc, P., Bernardi, R., Benchetrit, S., Akindele, K. and Vassal, G.
European Journal of Cancer 190
: 112950.
September 2023
Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance.
Pecorino, L.T., Verhaak, R.G.W., Henssen, A. and Mischel, P.S.
Biochemical Society Transactions 50
(6): 1911-1920.
December 2022
The role of CD4 T cells in rejection of solid tumors.
Poncette, L., Bluhm, J. and Blankenstein, T.
Current Opinion in Immunology 74
: 18-24.
February 2022
Special: biotech in Russia.
Rabinovich, M., Burghardt, N., Gorzka, G., Kudryashev, M., Leonov, A and Konov, A
Biotechnology Journal 2
(7): 775-789.
July 2007
MACC1 - the first decade of a key metastasis molecule from gene discovery to clinical translation.
Radhakrishnan, H., Walther, W., Zincke, F., Kobelt, D., Imbastari, F., Erdem, M., Kortüm, B., Dahlmann, M. and Stein, U.
Cancer and Metastasis Reviews 37
(4): 805-820.
December 2018
MHC class I-restricted antigen processing--lessons from natural ligands.
Rammensee, H.G., Roetzschke, O. and Falk, K.
Chemical Immunology 57
: 113-133.
1993
Single-cell genomics-based immune and disease monitoring in blood malignancies.
Rathgeber, A.C., Ludwig, L.S. and Penter, L.
Clinical Hematology International 6
(2): 62-84.
14 June 2024
Intricacies of single-cell multi-omics data integration.
Rautenstrauch, P., Vlot, A.H.C., Saran, S. and Ohler, U.
Trends in Genetics 38
(2): 128-139.
February 2022
Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia.
Regalo, G. and Leutz, A.
EMBO Molecular Medicine 5
(8): 1154-1164.
August 2013
Chemotherapy in alveolar soft part sarcomas: What do we know?
Reichardt, P., Lindner, T., Pink, D., Thuss-Patience, P.C., Kretzschmar, A. and Doerken, B.
European Journal of Cancer 39
(11): 1511-1516.
1 July 2003
Non-cell-autonomous tumor suppression: oncogene-provoked apoptosis promotes tumor cell senescence via stromal crosstalk.
Reimann, M., Schmitt, C.A. and Lee, S.
Journal of Molecular Medicine 89
(9): 869-875.
September 2011
Cellular senescence: Neither irreversible nor reversible.
Reimann, M., Lee, S. and Schmitt, C.A.
Journal of Experimental Medicine 221
(4): e20232136.
1 April 2024
Childhood cancer predisposition syndromes - a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.
Ripperger, T., Bielack, S.S., Borkhardt, A., Brecht, I.B., Burkhardt, B., Calaminus, G., Debatin, K.M., Deubzer, H., Dirksen, U., Eckert, C., Eggert, A., Erlacher, M., Fleischhack, G., Frühwald, M.C., Gnekow, A., Goehring, G., Graf, N., Hanenberg, H., Hauer, J., Hero, B., Hettmer, S., von Hoff, K., Horstmann, M., Hoyer, J., Illig, T., Kaatsch, P., Kappler, R., Kerl, K., Klingebiel, T., Kontny, U., Kordes, U., Körholz, D., Koscielniak, E., Kramm, C.M., Kuhlen, M., Kulozik, A.E., Lamottke, B., Leuschner, I., Lohmann, D.R., Meinhardt, A., Metzler, M., Meyer, L.H., Moser, O., Nathrath, M., Niemeyer, C.M., Nustede, R., Pajtler, K.W., Paret, C., Rasche, M., Reinhardt, D., Rieß, O., Russo, A., Rutkowski, S., Schlegelberger, B., Schneider, D., Schneppenheim, R., Schrappe, M., Schroeder, C., von Schweinitz, D., Simon, T., Sparber-Sauer, M., Spix, C., Stanulla, M., Steinemann, D., Strahm, B., Temming, P., Thomay, K., von Bueren, A.O., Vorwerk, P., Witt, O., Wlodarski, M., Wössmann, W., Zenker, M., Zimmermann, S., Pfister, S.M. and Kratz, C.P.
American Journal of Medical Genetics Part A 173
(4): 1017-1037.
April 2017
How to make tubes: signaling by the Met receptor tyrosine kinase.
Rosario, M. and Birchmeier, W.
Trends in Cell Biology 13
(6): 328-335.
June 2003
Transcription factors in myeloid development: balancing differentiation with transformation.
Rosenbauer, F. and Tenen, D.G.
Nature Reviews Immunology 7
(2): 105-117.
February 2007
Effect of transcription-factor concentrations on leukemic stem cells.
Rosenbauer, F., Koschmieder, S., Steidl, U. and Tenen, D.G.
Blood 106
: 1519-1524.
1 September 2005
The origins of ALK translocations.
Roukos, V. and Mathas, S.
Frontiers in Bioscience 7
: 260-268.
1 June 2015
Charting a DNA repair roadmap for immunoglobulin class switch recombination.
Saha, T., Sundaravinayagam, D. and Di Virgilio, M.
Trends in Biochemical Sciences 46
(3): 184-199.
March 2021
Review of preclinical data on hyperthermia treatment in lymphomas and its potential for clinical application.
Scharr, M.V., Damm, F., Krahl, P., Dieper, A., Veltsista, P.D., Hansch, A., Beck, M., Gerster, D., Giovannelli, A.C., Bullinger, L., Zips, D. and Ghadjar, P.
International Journal of Hyperthermia 41
(1): 2418427.
3 November 2024
IkappaB kinase complexes: gateways to NF-kappaB activation and transcription.
Scheidereit, C.
Oncogene 25
(51): 6685-6705.
30 October 2006
Sentinel node biopsy in gastrointestinal-tract cancer.
Schlag, P.M., Bembenek, A. and Schulze, T.
European Journal of Cancer 40
(14): 2022-2032.
September 2004
The tumour-Clostridium phenomenon: 50 years of developmental research.
Schmidt, W., Fabricius, E.M. and Schneeweiss, U.
International Journal of Oncology 29
(6): 1479-1492.
1 December 2006
Molecular principles of hair follicle induction and morphogenesis.
Schmidt-Ullrich, R. and Paus, R.
BioEssays 27
(3): 247-261.
15 February 2005
Cellular senescence and cancer treatment.
Schmitt, C.A.
Biochimica et Biophysica Acta - Reviews on Cancer 1775
(1): 5-20.
January 2007
Senescence apoptosis and therapy - cutting the lifelines of cancer.
Schmitt, C.A.
Nature Reviews Cancer 3
(4): 286-295.
April 2003
ASH highlights 2019: "aggressive B-cell lymphoma".
Schmitt, C.A.
memo: Magazine of European Medical Oncology 13
(3): 266-269.
20 May 2020
Senescence and cancer - role and therapeutic opportunities.
Schmitt, C.A., Wang, B. and Demaria, M.
Nature Reviews Clinical oncology 19
(10): 619–636.
October 2022
The SUMO pathway in pancreatic cancer: insights and inhibition.
Schneeweis, C., Hassan, Z., Schick, M., Keller, U. and Schneider, G.
British Journal of Cancer 124
(3): 531-538.
2 February 2021
The hair follicle as a dynamic miniorgan.
Schneider, M.R., Schmidt-Ullrich, R. and Paus, R.
Current Biology 19
(3): R132-T142.
10 February 2009
Rationale for MYC imaging and targeting in pancreatic cancer.
Schneider, G., Wirth, M., Keller, U. and Saur, D.
EJNMMI Research 11
(1): 104.
12 October 2021
The power of reversibility regulating gene activities via tetracycline-controlled transcription.
Schoenig, K., Bujard, H. and Gossen, M.
Methods in Enzymology 477
(C): 429-453.
2010
Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours.
Schubert, N.A., Chen, C.Y., Rodríguez, A., Koster, J., Dowless, M., Pfister, S.M., Shields, D.J., Stancato, L.F., Vassal, G., Caron, H.N., van den Boogaard, M.L., Henssen, A.G. and Molenaar, J.J.
European Journal of Cancer 170
: 196-208.
July 2022
Novel treatment options in head and neck cancer.
Schuler, P.J., Laban, S., Doescher, J., Bullinger, L. and Hoffmann, T.K.
Oncology Research and Treatment 40
(6): 342-346.
June 2017
Sentinel lymph node biopsy progress in surgical treatment of cancer.
Schulze, T., Bembenek, A. and Schlag, P.M.
Langenbecks Archives of Surgery 389
(6): 532-550.
November 2004
Notch and NF-κB signaling pathways in the biology of classical Hodgkin lymphoma.
Schwarzer, R. and Jundt, F.
Current Molecular Medicine 11
(3): 236-245.
April 2011
Chromatin dynamics during differentiation of myeloid cells.
Schönheit, J., Leutz, A. and Rosenbauer, F.
Journal of Molecular Biology 427
(3): 670-687.
13 February 2015
MACC1 revisited - an in-depth review of a master of metastasis.
Schöpe, P.C., Torke, S., Kobelt, D., Kortüm, B., Treese, C., Dumbani, M., Güllü, N., Walther, W. and Stein, U.
Biomarker Research 12
(1): 146.
23 November 2024
Expression profiling of leukemia patients: key lessons and future directions.
Shivarov, V. and Bullinger, L.
Experimental Hematology 42
(8): 651-60.
August 2014
Beyond stem cells: self-renewal of differentiated macrophages.
Sieweke, M.H. and Allen, J.E.
Science 342
(6161): 1242974.
22 November 2013
Coevolution between the human microbiota and the epithelial immune system.
Sigal, M. and Meyer, T.F.
Digestive Diseases 34
(3): 190-193.
March 2016
From regulation of cell fate decisions towards patient-specific treatments, insights from mechanistic models of signalling pathways.
Simon, M., Konrath, F. and Wolf, J.
Current Opinion in Systems Biology 39
: 100533.
December 2024
Instruction of mesenchymal cell fate by the transcription factor C/EBPbeta.
Smink, J.J. and Leutz, A.
Gene 497
(1): 10-17.
10 April 2012
Rapamycin and the transcription factor C/EBPbeta as a switch in osteoclast differentiation: implications for lytic bone diseases.
Smink, J.J. and Leutz, A.
Journal of Molecular Medicine 88
(3): 227-233.
March 2010
Compartment-specific functions of the ubiquitin-proteasome pathway.
Sommer, T., Jarosch, E. and Lenk, U.
Reviews of Physiology Biochemistry and Pharmacology 142
: 97-160.
2001
Endoplasmic reticulum degradation: reverse protein flow of no return.
Sommer, T. and Wolf, D.H.
FASEB Journal 11
: 1227-1233.
1 January 1997
Methods for lineage tracing on the organism-wide level.
Spanjaard, B. and Junker, J.P.
Current Opinion in Cell Biology 49
: 16-21.
December 2017
XDSAPP2.0.
Sparta, K.M., Krug, M., Heinemann, U., Mueller, U. and Weiss, M.S.
Journal of Applied Crystallography 49
(3): 1085-1092.
June 2016
Structural variation in the 3D genome.
Spielmann, M., Lupiáñez, D.G. and Mundlos, S.
Nature Reviews Genetics 19
(7): 453-467.
July 2018
MACC1 - a novel target for solid cancers.
Stein, U.
Expert Opinion on Therapeutic Targets 17
(9): 1039-1052.
September 2013
MACC1 - more than metastasis? Facts and predictions about a novel gene.
Stein, U., Dahlmann, M. and Walther, W.
Journal of Molecular Medicine 88
(1): 11-18.
January 2010
Clinical, biological, and molecular aspects of metastasis in colorectal cancer.
Stein, U. and Schlag, P.M.
Recent Results in Cancer Research 176
: 61-80.
2007
Antibiotic-perturbed microbiota and the role of probiotics.
Szajewska, H., Scott, K.P., de Meij, T., Forslund-Startceva, S.K., Knight, R., Koren, O., Little, P., Johnston, B.C., Łukasik, J., Suez, J., Tancredi, D.J. and Sanders, M.E.
Nature Reviews Gastroenterology & Hepatology
11 December 2024
(In Press)
Bone marrow GvHD after allogeneic hematopoietic stem cell transplantation.
Szyska, M. and Na, I.K.
Frontiers in Immunology 7
: 118.
30 March 2016
Keeping the proportions of protein complex components in check.
Taggart, J.C., Zauber, H., Selbach, M., Li, G.W. and McShane, E.
Cell Systems 10
(2): 125-132.
26 February 2020
Generation of memory B cells inside and outside germinal centers.
Takemori, T., Kaji, T., Takahashi, Y., Shimoda, M. and Rajewsky, K.
European Journal of Immunology 44
(5): 1258-1264.
May 2014
Central venous access catheters: radiological management of complications.
Teichgraeber, U.K., Gebauer, B., Benter, T. and Wagner, H.J.
Cardiovascular and Interventional Radiology 26
: 321-333.
1 July 2003
Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies.
Torke, S., Walther, W. and Stein, U.
Cancers 16
(7): 1330.
28 March 2024
The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review.
Van Paemel, R., Vlug, R., De Preter, K., Van Roy, N., Speleman, F., Willems, L., Lammens, T., Laureys, G., Schleiermacher, G., Tytgat, G.A.M., Astrahantseff, K., Deubzer, H. and De Wilde, B.
European Journal of Pediatrics 179
: 191-202.
February 2020
Opportunities and challenges in global quantification of RNA-protein interaction via UV cross-linking.
Vieira-Vieira, C.H. and Selbach, M.
Frontiers in Molecular Biosciences 8
: 669939.
13 May 2021
Applying synergy metrics to oncology combination screening data: agreements, disagreements and pitfalls.
Vlot, A.H.C., Aniceto, N., Menden, M.P., Ulrich-Merzenich, G. and Bender, A.
Drug Discovery Today 24
(12): 2286-2298.
December 2019
Targeted gene insertion for molecular medicine.
Voigt, K., Izsvak, Z. and Ivics, Z.
Journal of Molecular Medicine 86
(11): 1205-1219.
November 2008
Current status of gene therapy for cancer.
Walther, W. and Schlag, P.M.
Current Opinion in Oncology 25
(6): 659-664.
November 2013
Heat-responsive gene expression for gene therapy.
Walther, W. and Stein, U.
Advanced Drug Delivery Reviews 61
(7-8): 641-649.
2 July 2009
Low-volume jet injection for efficient nonviral in vivo gene transfer.
Walther, W., Stein, U., Fichtner, I. and Schlag, P.M.
Molecular Biotechnology 28
(2): 121-128.
1 January 2004
Getting to the root of branched ubiquitin chains: a review of current methods and functions.
Waltho, A. and Sommer, T.
Methods in Molecular Biology 2602
: 19-38.
2023
Oncogenic MYD88 mutations in lymphoma: novel insights and therapeutic possibilities.
Weber, A.N.R., Cardona Gloria, Y., Çınar, Ö., Reinhardt, H.C., Pezzutto, A. and Wolz, O.O.
Cancer Immunology Immunotherapy 67
(11): 1797-1807.
November 2018
Wnt signaling in stem and cancer stem cells.
Wend, P., Holland, J.D., Ziebold, U. and Birchmeier, W.
Seminars in Cell & Developmental Biology 21
(8): 855-863.
October 2010
Precision medicine in myeloid malignancies.
Westermann, J. and Bullinger, L.
Seminars in Cancer Biology 84
: 153-169.
September 2022
The regulatory potential of upstream open reading frames in eukaryotic gene expression.
Wethmar, K.
Wiley Interdisciplinary Reviews: RNA 5
(6): 765-768.
November 2014
Upstream open reading frames: molecular switches in (patho)physiology.
Wethmar, K., Smink, J.J. and Leutz, A.
BioEssays 32
(10): 885-893.
October 2010
The adaptive immune response to sporadic cancer.
Willimsky, G. and Blankenstein, T.
Immunological Reviews 220
(1): 102-112.
December 2007
Ubiquitination and ubiquitin-like modifications in multiple myeloma: biology and therapy.
Wirth, M., Schick, M., Keller, U. and Krönke, J.
Cancers 12
(12): 3764.
14 December 2020
Targeting histone deacetylases in neuroblastoma.
Witt, O., Deubzer, H.E., Lodrini, M., Milde, T. and Oehme, I.
Current Pharmaceutical Design 15
(4): 436-447.
2009
HDAC family: What are the cancer relevant targets?
Witt, O., Deubzer, H.E., Milde, T. and Oehme, I.
Cancer Letters 277
(1): 8-21.
8 May 2009
Responses of gastric epithelial stem cells and their niche to Helicobacter pylori infection.
Wizenty, J., Tacke, F. and Sigal, M.
Annals of Translational Medicine 8
(8): 568.
April 2020
Discovering novel hydrolases from hot environments.
Wohlgemuth, R., Littlechild, J., Monti, D., Schnorr, K., van Rossum, T., Siebers, B., Menzel, P., Kublanov, I.V., Rike, A.G., Skretas, G., Szabo, Z., Peng, X. and Young, M.J.
Biotechnology Advances 36
(8): 2077-2100.
December 2018
Atomistic Monte Carlo simulation of lipid membranes.
Wuestner, D. and Sklenar, H.
International Journal of Molecular Sciences 15
(2): 1767-803.
24 January 2014
Application of precision medicine in clinical routine in haematology - challenges and opportunities.
Wästerlid, T., Cavelier, L., Haferlach, C., Konopleva, M., Fröhling, S., Östling, P., Bullinger, L., Fioretos, T. and Smedby, K.E.
Journal of Internal Medicine 292
(2): 243-261.
August 2022
MicroRNA control in the immune system: basic principles.
Xiao, C. and Rajewsky, K.
Cell 136
(1): 26-36.
9 January 2009
MAP kinase cascades in antigen receptor signaling and physiology.
Yasuda, T.
Current Topics in Microbiology and Immunology 393
: 211-231.
2016
Extrachromosomal DNA amplifications in cancer.
Yi, E., Chamorro González, R., Henssen, A.G. and Verhaak, R.G.W.
Nature Reviews Genetics 23
(12): 760-771.
December 2022
Approaches and techniques to characterize cancer metabolism in vitro and in vivo.
Zaimenko, I., Lisec, J., Stein, U. and Brenner, W.
Biochimica et Biophysica Acta - Reviews on Cancer 1868
(2): 412-419.
December 2017
Pharmacogenomic strategies against resistance development in microbial infections.
Ziebuhr, W., Xiao, K., Coulibaly, B., Schwarz, R. and Dandekar, T.
Pharmacogenomics 5
(4): 361-379.
June 2004
Post-transplantation chronic myeloid leukemia.
le Coutre, P., Schwarz, M., Daniel, P. and Doerken, B.
Clinical Advances in Hematology & Oncology 9
(8): 627-629.
August 2011
An introduction to advanced targeted acquisition methods.
van Bentum, M. and Selbach, M.
Molecular & Cellular Proteomics 20
: 100165.
18 October 2021
Epigenetic control of myeloid cell differentiation, identity and function.
Álvarez-Errico, D., Vento-Tormo, R., Sieweke, M. and Ballestar, E.
Nature Reviews Immunology 15
(1): 7-17.
January 2015
The role of microbiota in primary sclerosing cholangitis and related biliary malignancies.
Özdirik, B., Müller, T., Wree, A., Tacke, F. and Sigal, M.
International Journal of Molecular Sciences 22
(13): 6975.
1 July 2021
Letter
Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML).
Agrawal, M., Schwarz, P., Giaimo, B.D., Bedzhov, I., Corbacioglu, A., Weber, D., Gaidzik, V.I., Jahn, N., Rücker, F.G., Schroeder, T., Kindler, T., Wattad, M., Götze, K., Lübbert, M., Salwender, H., Ringhoffer, M., Lange, E., Koller, E., Thol, F., Heuser, M., Ganser, A., Bullinger, L., Paschka, P., Döhner, H., Geiger, H., Borggrefe, T., Döhner, K. and Oswald, F.
Leukemia 34
(2): 630-634.
February 2020
Teclistamab-induced remission in refractory systemic lupus erythematosus.
Alexander, T., Krönke, J., Cheng, Q., Keller, U. and Krönke, G.
New England Journal of Medicine 391
(9): 864-866.
5 September 2024
Determinants of expression of SARS-CoV-2 entry related genes in upper and lower airways.
Aliee, H., Massip, F., Qi, C., de Biase, M.S., van Nijnatten, J., Kersten, E.T.G., Kermani, N.Z., Khuder, B., Vonk, J.M., Vermeulen, R.C.H., Neighbors, M., Tew, G.W., Grimbaldeston, M.A., Ten Hacken, N.H.T., Hu, S., Guo, Y., Zhang, X., Sun, K., Hiemstra, P.S., Ponder, B.A., Mäkelä, M.J., Malmström, K., Rintoul, R.C., Reyfman, P.A., Theis, F.J., Brandsma, C.A., Adcock, I.M., Timens, W., Xu, C.J., van den Berge, M., Schwarz, R.F., Koppelman, G.H., Nawijn, M.C. and Faiz, A.
Allergy 77
(2): 690-694.
February 2022
Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo.
Arreba-Tutusaus, P., Mack, T.S., Bullinger, L., Schnöder, T.M., Polanetzki, A., Weinert, S., Ballaschk, A., Wang, Z., Deshpande, A.J., Armstrong, S.A., Döhner, K., Fischer, T. and Heidel, F.H.
Leukemia 30
(5): 1220-1225.
May 2016
An idea whose time has come.
Banci, L., Baumeister, W., Heinemann, U., Schneider, G., Silman, I., Stuart, D.I. and Sussman, J.L.
Genome Biology 8
(11): 408.
7 November 2007
Varshavsky's contributions.
Baumeister, W., Bachmair, A., Chau, V., Cohen, R., Coffino, P., DeMartino, G., Deshaies, R., Dohmen, J., Emr, S., Finley, D., Hampton, R., Hill, C., Hochstrasser, M., Huber, R., Jackson, P., Jentsch, S., Johnson, E., Kwon, Y.T., Pagano, M., Pickart, C., Rechsteiner, M., Scheffner, M., Sommer, T., Tansey, W., Tyers, M., Vierstra, R., Weissman, A., Wilkinson, K.D. and Wolf, D.
Science 306
(5700): 1290-1292.
1 January 2004
A comparative analysis of human bone marrow-resident and peripheral memory B cells.
Becker, S.C., Szyska, M., Mensen, A., Hellwig, K., Otto, R., Olfe, L., Volk, H.D., Dörner, T., Dörken, B., Scheibenbogen, C., Schröder, J., Hocke, A.C. and Na, I.K.
Journal of Allergy and Clinical Immunology 141
(5): 1911-1913.
May 2018
Alternative perspective on the rationale for lymphatic mapping for sentinel node identification in colon cancer.
Bembenek, A.E. and Schlag, P.M.
Annals of Surgery 247
(5): 904.
May 2008
Need for safety goggles for endoscopy.
Benter, T., Kluehs, L., Teichgraeber, U.K.M., Riechert, F., Ludwig, W.D. and Doerken, B.
Endoscopy 35
(9): 803.
1 September 2003
Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient.
Bittner, A., Radke, J., Eurich, D., Wiener, E., Denker, S., Anagnostopoulos, I., Na, I.K., Heppner, F.L., Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 62
(8): 2026-2029.
August 2021
Gene expression profiling predicts sensitivity of chronic lymphocytic leukemia cells to dasatinib.
Blätte, T.J., Machnicki, M.M., Glodkowska-Mrowka, E., Dolnik, A., Karp, M., Karczmarczyk, A., Giannopoulos, K., Bullinger, L. and Stoklosa, T.
HemaSphere 5
(1): e514.
January 2021
getITD for FLT3-ITD-based MRD monitoring in AML.
Blätte, T.J., Schmalbrock, L.K., Skambraks, S., Lux, S., Cocciardi, S., Dolnik, A., Döhner, H., Döhner, K. and Bullinger, L.
Leukemia 33
(10): 2535-2539.
October 2019
Strong impact of extramedullary involvement in high-risk AML patients with active disease receiving the FLAMSA conditioning regimen for HSCT.
Bohl, S., von Harsdorf, S., Mulaw, M., Hofmann, S., Babiak, A., Maier, C.P., Schnell, J., Hütter-Krönke, L.M., Scholl, K., Wais, V., Schlenk, R.F., Bullinger, L., Ringhoffer, M., Döhner, H., Bunjes, D., Bommer, M. and Kuchenbauer, F.
Bone Marrow Transplantation 51
(7): 994-996.
July 2016
Gene expression analysis of decitabine treated AML: high impact of tumor suppressor gene expression changes.
Bohl, S.R., Dolnik, A., Jensen, T., Lang, K.M., Hackanson, B., Gaidzik, V.I., Paschka, P., Knudsen, S., Döhner, K., Döhner, H., Claus, R., Lübbert, M. and Bullinger, L.
Leukemia & Lymphoma 58
(9): 2264-2267.
2 September 2017
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Bourbon, H.M., Aguilera, A., Ansari, A.Z., Asturias, F.J., Berk, A.J., Bjorklund, S., Blackwell, T.K., Borggrefe, T., Carey, M., Carlson, M., Conaway, J.W., Conaway, R.C., Emmons, S.W., Fondell, J.D., Freedman, L.P., Fukasawa, T., Gustafsson, C.M., Han, M., He, X., Herman, P.K., Hinnebusch, A.G., Holmberg, S., Holstege, F.C., Jaehning, J.A., Kim, Y.J., Kuras, L., Leutz, A., Lis, J.T., Meisterernest, M., Naar, A.M., Nasmyth, K., Parvin, J.D., Ptashne, M., Reinberg, D., Ronne, H., Sadowski, I., Sakurai, H., Sipiczki, M., Sternberg, P.W., Stillman, D.J., Strich, R., Struhl, K., Svejstrup, J.Q., Tuck, S., Winston, F., Roeder, R.G. and Kornberg, R.D.
Molecular Cell 14
(5): 553-557.
1 January 2004
Genotype and intensive pretreatment influence outcome of acute myeloid leukemia patients treated with venetoclax in combination with hypomethylating agents or low-dose cytarabine: "real world" data from germany.
Braitsch, K., Schmalbrock, L.K., Jung, P., Bumeder, I., Kiewe, P., Hecker, J.S., Verbeek, M., Westermann, J., Bullinger, L., Keller, U., Bassermann, F., Krönke, J., Götze, K.S. and Rieger, K.
HemaSphere 6
(9): e759.
September 2022
T cell PTLD successfully treated with single-agent brentuximab vedotin first-line therapy.
Choi, M., Fink, S., Prasad, V., Anagnostopoulos, I., Reinke, P. and Schmitt, C.A.
Transplantation 100
(3): e8-e10.
March 2016
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Dahlmann, M., Gambara, G., Brzezicha, B., Popp, O., Pachmayr, E., Wedeken, L., Pflaume, A., Mokritzkij, M., Gül-Klein, S., Brandl, A., Schweiger-Eisbacher, C., Mertins, P., Hoffmann, J., Keilholz, U., Walther, W., Regenbrecht, C., Rau, B. and Stein, U.
Molecular Cancer 20
(1): 129.
21 October 2021
Authors' reply: Treatment of oesophageal anastomotic leaks by temporary stenting with self-expanding plastic stents (Br J Surg 2009; 96: 887-891).
Dai, Y.Y., Gretschel, S., Dudeck, O., Rau, B., Schlag, P.M. and Huenerbein, M.
British Journal of Surgery 97
(2): 294-295.
February 2010
Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group.
Damaschin, C., Goergen, H., Kreissl, S., Plütschow, A., Breywisch, F., Mathas, S., Meissner, J., Sökler, M., Topp, M.S., Vucinic, V., Zimmermann, A., von Tresckow, B., Fuchs, M., Engert, A., Borchmann, P. and Eichenauer, D.A.
Leukemia 36
(2): 580-582.
February 2022
Randomized, phase 3 trial of inotuzumab ozogamicin plus rituximab versus chemotherapy plus rituximab for relapsed/refractory aggressive B-cell non-Hodgkin lymphoma.
Dang, N.H., Ogura, M., Castaigne, S., Fayad, L.E., Jerkeman, M., Radford, J., Pezzutto, A., Bondarenko, I., Stewart, D.A., Shnaidman, M., Sullivan, S., Vandendries, E., Tobinai, K., Ramchandren, R., Hamlin, P.A., Giné, E. and Ando, K.
British Journal of Haematology 182
(4): 583-586.
August 2018
Auto gegen Pferd - zur Schnellschnitt-Diagnostik per Telepathologie.
Dietel, M., Dierks, C., Hufnagl, P. and Schlag, P.M.
Pathologe 21
(5): 391-393.
1 September 2000
A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire.
Dobeš, J., Edenhofer, F., Vobořil, M., Brabec, T., Dobešová, M., Čepková, A., Klein, L., Rajewsky, K. and Filipp, D.
European Journal of Immunology 48
(3): 546-548.
March 2018
Genome sequencing in myeloid cancers.
Dolnik, A., Schrezenmeier, J. and Bullinger, L.
New England Journal of Medicine 384
(25): e106.
24 June 2021
Perspectives on unidirectional versus divergent transcription.
Duttke, S.H.C., Lacadie, S.A., Ibrahim, M.M., Glass, C.K., Corcoran, D.L., Benner, C., Heinz, S., Kadonaga, J.T. and Ohler, U.
Molecular Cell 60
(3): 348-349.
5 November 2015
Clonal hematopoiesis of indeterminate potential-related epigenetic age acceleration correlates with clonal hematopoiesis of indeterminate potential clone size in patients with high morbidity.
Feldkamp, J.D., Vetter, V.M., Arends, C.M., Lang, T.J.L., Bullinger, L., Damm, F., Demuth, I. and Frick, M.
Haematologica 107
(7): 1703-1708.
July 2022
Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL network phase II trial.
Ferrero, S., Pastore, A., Scholz, C.W., Forstpointner, R., Pezzutto, A., Bergmann, L., Truemper, L., Finke, J., Keller, U., Ghione, P., Passera, R., Hiddemann, W., Weigert, O., Unterhalt, M. and Dreyling, M.
Leukemia 30
(4): 984-987.
April 2016
1H, 13C and 15N resonance assignments of the C-terminal BRCT domain from human BRCA1.
Gaiser, O.J., Oschkinat, H., Heinemann, U. and Ball, L.J.
Journal of Biomolecular NMR 30
(2): 221-222.
1 January 2004
Practice and effectiveness of outpatient psycho-oncological counseling for cancer patients.
Goerling, U., Tagmat, D., Muffler, E., Schramm, N., Wernecke, K.D. and Schlag, P.M.
Journal of Cancer 1
: 112-119.
23 August 2010
The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Grasedieck, S., Ruess, C., Krowiorz, K., Lux, S., Pochert, N., Schwarzer, A., Klusmann, J.H., Jongen-Lavrencic, M., Herold, T., Bullinger, L., Pollack, J.R., Rouhi, A. and Kuchenbauer, F.
Haematologica 105
(9): e448-e453.
September 2020
Acute myeloid leukemia with mutated nucleophosmin 1: an immunogenic acute myeloid leukemia subtype and potential candidate for immune checkpoint inhibition.
Greiner, J., Hofmann, S., Schmitt, M., Götz, M., Wiesneth, M., Schrezenmeier, H., Bunjes, D., Döhner, H. and Bullinger, L.
Haematologica 102
(12): e499-e501.
December 2017
Subacute coronary stent thrombosis in cancer patients.
Gross, C.M., Posch, M.G., Geier, C., Olthoff, H., Kraemer, J., Dechend, R., Dietz, R. and Oezcelik, C.
Journal of the American College of Cardiology 51
(12): 1232-1233.
25 March 2008
Horizontal gene transfer of two cytoskeletal elements from a eukaryote to a cyanobacterium.
Guljamow, A., Jenke-Kodama, H., Saumweber, H., Quillardet, P., Frangeul, L., Castets, A.M., Bouchier, C., Tandeau de Marsac, N. and Dittmann, E.
Current Biology 17
(17): R757-R759.
4 September 2007
The BRCA2 variant 8204G>A is a splicing mutation and results in an in frame deletion of the gene.
Hofmann, W., Horn, D., Huettner, C., Classen, E. and Scherneck, S.
Journal of Medical Genetics 40
: e23.
1 March 2003
Three-dimensional ultrasound cholangiography: a new noninvasive technique for evaluation of biliary obstruction (Comment on: Am J Gastroenterol. 2001 Jul;96(7):1959-60, Am J Gastroenterol. 2001 Jul;96(7):2074-80).
Huenerbein, M., Stroszczynski, C., Felix, R. and Schlag, P.M.
American Journal of Gastroenterology 97
(2): 500-501.
February 2002
Ductoscopic biopsy of papillary tumors in women with nipple discharge.
Huenerbein, M. and Schlag, P.M.
Annals of Surgery 245
(1): 154-155.
January 2007
Evaluation of pathologic nipple discharge with ductoscopy.
Huenerbein, M., Schwarz, L.E., Schneider, U. and Schlag, P.M.
Journal of the American College of Surgeons 197
(4): 697-698.
October 2003
Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda et al.
Immisch, L., Papafotiou, G., Popp, O., Mertins, P., Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 11
(3): e006784.
14 March 2023
Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia.
In't Hout, F.E.M., Gerritsen, M., Bullinger, L., Van der Reijden, B.A., Huls, G., Vellenga, E. and Jansen, J.H.
Haematologica 105
(9): e454-457.
1 September 2020
Hungary's 'reforms' are threatening basic science.
Izsvak, Z., Ivics, Z. and Mates, L.
Nature 443
(7110): 394.
28 September 2006
Incidence and prognostic impact of ASXL2 mutations in adult acute myeloid leukemia patients with t(8;21)(q22;q22): a study of the German-Austrian AML Study Group.
Jahn, N., Agrawal, M., Bullinger, L., Weber, D., Corbacioglu, A., Gaidzik, V.I., Schmalbrock, L., Thol, F., Heuser, M., Krauter, J., Göhring, G., Kündgen, A., Fiedler, W., Wattad, M., Held, G., Köhne, C.H., Horst, H.A., Lübbert, M., Ganser, A., Schlenk, R.F., Döhner, H., Döhner, K. and Paschka, P.
Leukemia 31
(4): 1012-1015.
April 2017
Expression of the chemokine receptors CXCR4, CXCR5, and CCR7 in primary central nervous system lymphoma.
Jahnke, K., Coupland, S.E., Na, I.K., Loddenkemper, C., Keilholz, U., Korfel, A., Stein, H., Thiel, E. and Scheibenbogen, C.
Blood 106
(1): 384-385.
1 July 2005
A randomized open label phase-II clinical trial with or without infusion of plasma from subjects after convalescence of SARS-CoV-2 infection in high-risk patients with confirmed severe SARS-CoV-2 disease (RECOVER): a structured summary of a study protocol for a randomised controlled trial.
Janssen, M., Schäkel, U., Djuka Fokou, C., Krisam, J., Stermann, J., Kriegsmann, K., Haberbosch, I., Novotny, J.P., Weber, S., Vehreschild, M., Bornhäuser, M., Bullinger, L., Schmitt, M., Liebregts, T., Dreger, P., Lorenz, H.M., Plaszczyca, A., Bartenschlager, R., Müller, B., Kräusslich, H.G., Halama, N., Jäger, D., Schlenk, R.F., Leo, A., Meuer, S., Weigand, M.A., Motsch, J., Merle, U., Denkinger, C.M. and Müller-Tidow, C.
Trials 21
(1): 828.
6 October 2020
Differential expression of SHP-1 in chronic myeloid leukemia.
Kaeda, J., Neuman, D., Bonecker, S., Mills, K., Oberender, C., Amini, L., Ringel, F., Serra, A., Schwarz, M., Doerken, B., Zalcberg, I. and Le Coutre, P.
Leukemia & Lymphoma 56
(5): 1547-1549.
May 2015
Long-term follow-up of patients with Philadelphia chromosome-positive chronic myeloid leukemia after stem cell mobilization under imatinib.
Kim, T.D., Schwarz, M., Kreuzer, K.A., Kaeda, J., Movassaghi, K., Grille, P., Daniel, P.T., Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 52
(3): 517-520.
March 2011
Hydrolysis of extracellular ATP by CD39+ Treg cells: context matters!
Kleinewietfeld, M., Dimitri, D., Sternjak, A., Diamantini, A., Borsellino, G., Battistini, L., Roetzschke, O. and Falk, K.
Blood 111
(2): 965-966.
15 January 2008
NF-κB activity is required for anagen maintenance in human hair follicles in vitro.
Kloepper, J.E., Ernst, N., Krieger, K., Bodo, E., Biro, T., Haslam, I.S., Schmidt-Ullrich, R. and Paus, R.
Journal of Investigative Dermatology 134
(7): 2036-2038.
11 February 2014
Simplified preanalytical laboratory procedures for therapeutic drug monitoring (TDM) in patients treated with high-dose methotrexate (HD-MTX) and glucarpidase.
Knörnschild, F.L., Liebig, S., Kießling, P., Prpic, M., Kim, T., Keller, U., Kappert, K., Schwartz, S. and Jahic, A.
Clinical Chemistry and Laboratory Medicine 63
(1): e11-e15.
2025
Frequent, high density expression of surface CD38 as a potential therapeutic target in adult T-lineage acute lymphoblastic leukemia.
Koslowski, S., Glauben, R., Habringer, S., Burmeister, T., Keller, U., Brüggemann, M., Gökbuget, N. and Schwartz, S.
Haematologica 109
(2): 661-665.
February 2024
The DNA methylation status of the TERT promoter differs between subtypes of mature B-cell lymphomas.
Kouroukli, A.G., Fischer, A., Kretzmer, H., Chteinberg, E., Rajaram, N., Glaser, S., Kolarova, J., Bashtrykov, P., Mathas, S., Drexler, H.G., Ohno, H., Ammerpohl, O., Jeltsch, A., Siebert, R. and Bens, S.
Blood Cancer Journal 13
(1): 98.
26 June 2023
Extravasations of oxaliplatin.
Kretzschmar, A., Pink, D., Thuss-Patience, P., Doerken, B., Reichert, P. and Eckert, R.
Journal of Clinical Oncology 21
(21): 4068-4069.
1 November 2003
MiR-139-5p is a potent tumor suppressor in adult acute myeloid leukemia.
Krowiorz, K., Ruschmann, J., Lai, C., Ngom, M., Maetzig, T., Martins, V., Scheffold, A., Schneider, E., Pochert, N., Miller, C., Palmqvist, L., Staffas, A., Mulaw, M., Bohl, S.R., Buske, C., Heuser, M., Kraus, J., O'Neill, K., Hansen, C.L., Petriv, O.I., Kestler, H., Döhner, H., Bullinger, L., Döhner, K., Humphries, R.K., Rouhi, A. and Kuchenbauer, F.
Blood Cancer Journal 6
(12): e508.
December 2016
A high proportion of germline variants in pediatric chronic myeloid leukemia.
Krumbholz, M., Dolnik, A., Sträng, E., Ghete, T., Skambraks, S., Hutter, S., Simonis, A., Stegelmann, F., Suttorp, M., Horn, A.H.C., Sticht, H., Haferlach, T., Bullinger, L. and Metzler, M.
Molecular Cancer 23
(1): 206.
26 September 2024
A phase I study of MAGE-A1-targeted T1367 T-cell receptor-based cell therapy in patients with advanced multiple myeloma.
Krüger, J., Obenaus, M., Blau, I.W., Hoser, D., Vaegler, M., Rauschenbach, H., Anagnostopoulos, I., Jöhrens, K., Scheuplein, V., Kieback, E., Böhme, J., Von Brünneck, A.C., Krönke, J., Busse, A., Willimsky, G., Blankenstein, T., Pezzutto, A., Keller, U. and Nogai, A.
Haematologica
12 September 2024
(In Press)
Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B cell impairment and increases the risk for infections - a retrospective matched cohort study.
Launspach, M., Temel, D., Ohlendorf, E., Zirngibl, F., Materne, B., Oevermann, L., Deubzer, H.E., Henssen, A.G., Künkele, A., Hundsdörfer, P., von Bernuth, H., Pruß, A., Eggert, A., von Stackelberg, A., Lang, P. and Schulte, J.H.
Haematologica 108
(1): 267-272.
January 2023
Severe peripheral arterial disease during nilotinib therapy.
Le Coutre, P., Rea, D., Abruzzese, E., Dombret, H., Trawinska, M.M., Herndlhofer, S., Doerken, B. and Valent, P.
Journal of the National Cancer Institute 103
(17): 1347-1348.
7 September 2011
Extracorporeal photopheresis in graft-versus-host disease: ultraviolet radiation mediates T cell senescence in vivo.
Lee, S., Doerken, B. and Schmitt, C.A.
Transplantation 78
(3): 484-485.
15 August 2004
Humoral and cellular immune responses in SARS-CoV-2 mRNA-vaccinated patients with cancer.
Mairhofer, M., Kausche, L., Kaltenbrunner, S., Ghanem, R., Stegemann, M., Klein, K., Pammer, M., Rauscher, I., Salzer, H.J.F., Doppler, S., Habringer, A., Paar, C., Kimeswenger, S., Hoetzenecker, W., Lamprecht, B., Lee, S. and Schmitt, C.A.
Cancer Cell 39
(9): 1171-1172.
13 September 2021
Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Martin-Subero, J.I., Wlodarska, I., Bastard, C., Picquenot, J.M., Hoeppner, J., Giefing, M., Klapper, W., Siebert, R., Mathas, S., Joos, S., Stein, H. and Doerken, B.
Blood 108
: 401-403.
1 July 2006
Cellular origin of prognostic chromosomal aberrations in AML patients.
Mora-Jensen, H., Jendholm, J., Rapin, N., Andersen, M.K., Roug, A.S., Bagger, F.O., Bullinger, L., Winther, O., Borregaard, N., Porse, B.T. and Theilgaard-Mönch, K.
Leukemia 29
(8): 1785-9.
August 2015
Standardized annotation of translated open reading frames.
Mudge, J.M., Ruiz-Orera, J., Prensner, J.R., Brunet, M.A., Calvet, F., Jungreis, I., Gonzalez, Jo.M., Magrane, M., Martinez, T.F., Schulz, J.F., Yang, Y.T., Albà, M.M., Aspden, J.L., Baranov, P.V., Bazzini, A.A., Bruford, E., Martin, M.J., Calviello, L., Carvunis, A.R., Chen, J., Couso, J.P., Deutsch, E.W., Flicek, P., Frankish, A., Gerstein, M., Hubner, N., Ingolia, N.T., Kellis, M., Menschaert, G., Moritz, R.L., Ohler, U., Roucou, X., Saghatelian, A., Weissman, J.S. and van Heesch, S.
Nature Biotechnology 40
(7): 994–999.
July 2022
High-dose glucocorticoid treatment of near-fatal Bocavirus lung infection results in rapid recovery.
Obenaus, M., Schildgen, O., Schürmann, D., von Brünneck, A.C., Janz, M., Keller, U., Gebauer, B., Schilling, J., Schwartz, S., Weissbrich, B., Schneider, T., Hofmann, J. and Mathas, S.
ERJ Open Research 7
(2): 00060-2021.
12 April 2021
Sequencing of NUMB transcripts in chronic myeloid leukaemia detects two single nucleotide polymorphisms.
Oberender, C., Kaeda, J., Pawlaczyk-Peter, B., Daniel, P., Arnold, R., Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 54
(2): 421-422.
February 2013
Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications.
Oevermann, L., Zimmermann, C., Voigt, S., Künkele, A., Lobitz, S., Eggert, A., Schulte, J.H., Kaufer, B.B. and Deubzer, H.E.
Bone Marrow Transplantation 55
(1): 260-264.
January 2020
A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.
Pieper, K., Rizzi, M., Speletas, M., Smulski, C.R., Sic, H., Kraus, H., Salzer, U., Fiala, G.J., Schamel, W.W., Lougaris, V., Plebani, A., Hammarstrom, L., Recher, M., Germenis, A.E., Grimbacher, B., Warnatz, K., Rolink, A.G., Schneider, P., Notarangelo, L.D. and Eibel, H.
Journal of Allergy and Clinical Immunology 133
(4): 1222-1225.
April 2014
A cancer immunosurveillance controversy.
Qin, Z.H. and Blankenstein, T.
Nature Immunology 5
(1): 3-4.
1 January 2004
Safety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part phase Ib/II study.
Rambaldi, A., Iurlo, A., Vannucchi, A.M., Noble, R., von Bubnoff, N., Guarini, A., Martino, B., Pezzutto, A., Carli, G., De Muro, M., Luciani, S., McMullin, M.F., Cambier, N., Marolleau, J.P., Mesa, R.A., Tibes, R., Pancrazzi, A., Gesullo, F., Bettica, P., Manzoni, S. and Di Tollo, S.
Leukemia 34
(8): 2234-2237.
August 2020
Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia.
Rapaport, F., Neelamraju, Y., Baslan, T., Hassane, D., Gruszczynska, A., de Massy, M.R., Farnoud, N., Haddox, S., Lee, T., Medina-Martinez, J., Sheridan, C., Thurmond, A., Becker, M., Bekiranov, S., Carroll, M., Moses Murdock, H., Valk, P.J.M., Bullinger, L., D’Andrea, R., Lowe, S.W., Neuberg, D., Levine, R.L., Melnick, A. and Garrett-Bakelman, F.E.
Leukemia 35
(9): 2688-2692.
September 2021
In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.
Roetzschke, O., Borsellino, G., Battistini, L., Falk, K. and Kleinewietfeld, M.
Blood 113
(9): 2119-2120.
26 February 2009
Refinement of the prognostic impact of somatic CEBPA bZIP domain mutations in acute myeloid leukemia: Results of the AML Study Group (AMLSG).
Rücker, F.G., Corbacioglu, A., Krzykalla, J., Cocciardi, S., Lengerke, C., Germing, U., Wulf, G., Samra, M.A., Teichmann, L.L., Lübbert, M., Kühn, M.W.M., Bentz, M., Westermann, J., Bullinger, L., Gaidzik, V.I., Meid, A., Aicher, S., Stegelmann, F., Weber, D., Schrade, A., Thol, F., Heuser, M., Ganser, A., Benner, A., Döhner, H. and Döhner, K.
HemaSphere 8
(7): e123.
July 2024
Chromothripsis is linked to alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype.
Rücker, F.G., Dolnik, A., Blätte, T.J., Teleanu, V., Ernst, A., Thol, F., Heuser, M., Ganser, A., Döhner, H., Döhner, K. and Bullinger, L.
Haematologica 103
(1): e17-e20.
January 2018
Authors' reply: Surgical strategies for gastric cancer with synchronous peritoneal carcinomatosis (Br J Surg 2006; 93: 1530-1535).
Schlag, P.M.
British Journal of Surgery 94
(5): 642-643.
May 2007
Tet-Transgenic Rodents: a comprehensive, up-to date database.
Schoenig, K., Freundlieb, S. and Gossen, M.
Transgenic Research 22
(2): 251-254.
April 2013
Characterization of apoptosis-induced Mcm3 and Cdc6 cleavage reveals a proapoptotic effect for one Mcm3 fragment.
Schories, B., Engel, K., Doerken, B., Gossen, M. and Bommert, K.
Cell Death and Differentiation 11
(8): 940-942.
August 2004
Induction of circulating ABCB1 transcripts under platinum-based chemotherapy indicates poor prognosis and a bone micrometastatic phenotype in ovarian cancer patients.
Schwarz, F.M., Kuhlmann, J.D., Kämpfer, J., Klimova, A., Klotz, D.M., Freitag, L., Herrmann, P., Zinnow, V., Smith, J., Scheller, T., Walther, W., Wimberger, P. and Stein, U.
Molecular Cancer 23
(1): 174.
23 August 2024
Notch inhibition blocks multiple myeloma cell-induced osteoclast activation.
Schwarzer, R., Kaiser, M., Acikgoez, O., Heider, U., Mathas, S., Preissner, R., Sezer, O., Doerken, B. and Jundt, F.
Leukemia 22
(12): 2273-2277.
December 2008
MicroRNA expression-based outcome prediction in acute myeloid leukemia: novel insights through cross-platform integrative analyses.
Shivarov, V., Dolnik, A., Lang, K.M., Krönke, J., Kuchenbauer, F., Paschka, P., Gaidzik, V.I., Döhner, H., Schlenk, R.F., Döhner, K. and Bullinger, L.
Haematologica 101
(11): e454-e456.
November 2016
Deletions in the long arm of chromosome 10 in lymphomas with t(14;18): A pathogenetic role of the tumor suppressor genes PTEN/MMAC1 and MXI1?
Siebert, R., Gesk, S., Harder, S., Ploetz, S., Matthiesen, P., Grote, W., Schlegelberger, B., Jandrig, B., Grasmo-Wendler, U.H., Scherneck, S., Rosenwald, A. and Ott, G.
Blood 92
(11): 4487-4489.
1 December 1998
MACC1 controls Met: What a difference an Sp1 site makes.
Stein, U., Smith, J., Walther, W. and Arlt, F.
Cell Cycle 8
(15): 2467-2469.
1 August 2009
High HSP70-membrane expression on leukemic cells from patients with acute myeloid leukemia is associated with a worse prognosis.
Steiner, K., Graf, M., Hecht, K., Reif, S., Rossbacher, L., Pfister, K., Kolb, H.J., Schmetzer, H.M. and Multhoff, G.
Leukemia 20
(11): 2076-2079.
November 2006
Polymerase chain reaction monitoring shows a high efficacy of clinical immunomagnetic purging in patients with centroblastic- centrocytic non-Hodgkin's lymphoma.
Straka, C., Kroner, C., Doerken, B. and Kvalheim, G.
Blood 80
(10): 2688-2690.
15 November 1992
Insulin-like growth factor-I and risk of breast cancer.
Strohm, O., Osterziel, K.J. and Dietz, R.
Lancet 352
(9126): 489-489.
8 August 1998
Extramedullary manifestation of a donor-derived acute myeloid leukemia in a liver transplant patient.
Subklewe, M., Nagy, M., Schoch, C., Jenisch, S., Siebert, R., Gesk, S., Neuhaus, P., Doerken, B. and Schmidt, C.A.
Leukemia 18
(12): 2050-2053.
7 October 2004
Clone wars?
Tannert, C.
EMBO Reports 7
(7): 656.
1 July 2006
NIH-defined graft-versus-host disease after reduced intensity or myeloablative conditioning in patients with acute myeloid leukemia.
Terwey, T.H., Vega-Ruiz, A., Hemmati, P.G., Martus, P., Dietz, E., le Coutre, P., Massenkeil, G., Doerken, B. and Arnold, R.
Leukemia 26
(3): 536-542.
March 2012
Clinical impact of GATA2 mutations in acute myeloid leukemia patients harboring CEBPA mutations: a study of the AML study group.
Theis, F., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Weber, D., Bullinger, L., Heuser, M., Ganser, A., Thol, F., Schlegelberger, B., Göhring, G., Köhne, C.H., Germing, U., Brossart, P., Horst, H.A., Haase, D., Götze, K., Ringhoffer, M., Fiedler, W., Nachbaur, D., Kindler, T., Held, G., Lübbert, M., Wattad, M., Salih, H.R., Krauter, J., Döhner, H., Schlenk, R.F. and Döhner, K.
Leukemia 30
(11): 2248-2250.
November 2016
Acute hypokalemic tetraparesis induced by intravenous methotrexate.
Thuss-Patience, P.C., Peters, U., Jurkat-Rott, K., Pink, D., Kretzschmar, A., Doerken, B. and Reichardt, P.
Journal of Clinical Oncology 21
(9): 1896-1897.
1 May 2003
Successful treatment of thrombocytopenia in primary antiphospholipid antibody syndrome with the anti-CD20 antibody rituximab-monitoring of antiphospholipid and anti-GP antibodies: a case report.
Trappe, R., Loew, A., Thuss-Patience, P., Doerken, B. and Riess, H.
Annals of Hematology 85
: 134-135.
February 2006
Confounding in ex vivo models of Diamond-Blackfan anemia.
Ulirsch, J.C., Lareau, C., Ludwig, L.S., Mohandas, N., Nathan, D.G. and Sankaran, V.G.
Blood 130
(9): 1165-1168.
31 August 2017
The IL-15 cytokine system provides growth and survival signals in hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells.
Ullrich, K., Blumenthal-Barby, F., Lamprecht, B., Koechert, K., Lenze, D., Hummel, M., Mathas, S., Doerken, B. and Janz, M.
Leukemia 29
(5): 1213-1218.
May 2015
BAY 43-9006/Sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines.
Ullrich, K., Wurster, K.D., Lamprecht, B., Koechert, K., Engert, A., Doerken, B., Janz, M. and Mathas, S.
British Journal of Haematology 155
(3): 398-402.
November 2011
Reduced-toxicity conditioning for allogeneic hematopoietic cell transplantation in elderly or comorbid patients with AML using fludarabine, BCNU and melphalan: disease stage at transplant determines outcome.
Wais, V., Kündgen, L., Bohl, S.R., von Harsdorf, S., Schlenk, R.F., Döhner, K., Teleanu, V., Bullinger, L., Nguyen, T.M., Drognitz, K., Moulin, J.C., Binnenhei, M., Bentz, M., Döhner, H., Bunjes, D., Kuchenbauer, F. and Ringhoffer, M.
Bone marrow transplantation 53
(1): 94-96.
January 2018
Author reply: Polyclonal resistance in gastrointestinal stromal tumor treated with sequential kinase inhibitors.
Wardelmann, E., Biermann, K., Merkelbach-Bruse, S., Thomas, N., Schildhaus, H.U., Heinicke, T., Speidel, N., Pietsch, T., Buettner, R., Pink, D., Reichardt, P. and Hohenberger, P.
Clinical Cancer Research 12
(20): 6206-6207.
15 October 2006
A peculiar case of primary central nervous system T-cell lymphoma with indolent behavior.
Wasilewski, D., Janz, M., Koch, A., Rosenwald, A., Keller, U., Vajkoczy, P., Faust, K., Anagnostopoulos, I. and Radke, J.
Acta Neurologica Belgica 123
(2): 667-670.
April 2022
Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.
Wuchter, C., Richter, S., Oltersdorf, D., Karawajew, L., Ludwig, W.D. and Tamm, I.
Haematologica 89
: 363-364.
1 March 2004
Early references to the mutational origin of cancer.
Wunderlich, V.
International Journal of Epidemiology 36
(1): 246-247.
February 2007
"Tumour suppressor gene" concept of carcinogenesis.
Wunderlich, V. and Rajewsky, M.F.
Lancet 345
(8964): 1570-1571.
17 June 1995
Synergistic effect of tamoxifen and phorbol ester TPA on retrovirus synthesis in a human mammary carcinoma cell line.
Wunderlich, V. and Stein, U.
International Journal of Cancer 56
(4): 615-616.
15 February 1994
Expression of CD274 (PD-L1) is associated with unfavourable recurrent mutations in AML.
Zajac, M., Zaleska, J., Dolnik, A., Bullinger, L. and Giannopoulos, K.
British Journal of Haematology 183
(5): 822-825.
December 2018
Picky: a simple online PRM and SRM method designer for targeted proteomics.
Zauber, H., Kirchner, M. and Selbach, M.
Nature Methods 15
(3): 156-157.
28 February 2018
Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations.
van den Brink, S.C., Sage, F., Vertesy, A., Spanjaard, B., Peterson-Maduro, J., Baron, C.S., Robin, C. and van Oudenaarden, A.
Nature Methods 14
(10): 935-936.
29 September 2017
Interruption of the CXCL13/CXCR5 chemokine axis enhances plasma IgM levels and attenuates atherosclerosis development.
van der Vorst, E.P.C., Daissormont, I., Aslani, M., Seijkens, T., Wijnands, E., Lutgens, E., Duchene, J., Santovito, D., Döring, Y., Halvorsen, B., Aukrust, P., Weber, C., Höpken, U.E. and Biessen, E.A.L.
Thrombosis and Haemostasis 120
(2): 344-347.
February 2020
Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies.
Çakmak-Görür, N., Radke, J., Rhein, S., Schumann, E., Willimsky, G., Heppner, F.L., Blankenstein, T. and Pezzutto, A.
Leukemia 33
(4): 1039-1043.
April 2019
Editorial
KCNE2 and gastric cancer: bench to bedside.
Abbott, G.W. and Roepke, T.K.
Oncotarget 7
(14): 17286-17287.
5 April 2016
Wenn Symptome im Vordergrund stehen [When Symptoms are paramount].
Adamietz, I. A. and Schlag, P. M.
Onkologe 19
(4): 262-264.
April 2013
Time for progress.
Adler, G. and Schlag, P.M.
Onkologie 27
(1): 11.
February 2004
S3-guideline "exocrine pancreatic carcinoma" 2007 : Results of an Evidence-Based Consensus Conference (13. - 14.10.2006).
Adler, G., Seufferlein, T., Bischoff, S.C., Brambs, H.J., Feuerbach, S., Grabenbauer, G., Hahn, S., Heinemann, V., Hohenberger, W., Langrehr, J.M., Lutz, M.P., Micke, O., Neuhaus, H., Neuhaus, P., Oettle, H., Schlag, P.M., Schmid, R., Schmiegel, W., Schlottmann, K., Werner, J., Wiedenmann, B. and Kopp, I.
Zeitschrift fuer Gastroenterologie 46
(5): 449-482.
May 2008
Vom "Stiefkind" zum Paradebeispiel [From "stepchild" to classic example].
Al-Batran, S.E. and Schlag, P.M.
Onkologe 19
(5): 350.
May 2013
Protein quality control: On IPODs and other JUNQ.
Bagola, K. and Sommer, T.
Current Biology 18
(21): R1019-R1021.
11 November 2008
Structural proteomics: from the molecule to the system.
Banci, L., Baumeister, W., Enfedaque, J., Heinemann, U., Schneider, G., Silman, I. and Sussman, J.L.
Nature Structural & Molecular Biology 14
(1): 3-4.
January 2007
Enhanced precision and efficiency.
Bashir, S. and Kühn, R.
Nature Biomedical Engineering 1
(11): 856-857.
November 2017
Can the presence of micrometastases in patients with colorectal cancer be used to help guide treatment?
Bembenek, A. and Schlag, P.M.
Nature Clinical Practice Gastroenterology & Hepatology 5
(5): 244-245.
May 2008
Stem cell biology-from basic research to regenerative medicine.
Besser, D.
Journal of Molecular Medicine 90
(7): 731-733.
July 2012
Orchestrating Wnt signalling for metabolic liver zonation.
Birchmeier, W.
Nature Cell Biology 18
(5): 463-465.
May 2016
Stem cells: Orphan receptors find a home.
Birchmeier, W.
Nature 476
(7360): 287-288.
18 August 2011
Cell adhesion and signal transduction in cancer.
Birchmeier, W.
EMBO Reports 6
(5): 413-417.
1 January 2005
A resource of targeted mutant mouse lines for 5,061 genes.
Birling, M.C., Yoshiki, A., Adams, D.J., Ayabe, S., Beaudet, A.L., Bottomley, J., Bradley, A., Brown, S.D.M., Bürger, A., Bushell, W., Chiani, F., Chin, H.J.G., Christou, S., Codner, G.F., DeMayo, F.J., Dickinson, M.E., Doe, B., Donahue, L.R., Fray, M.D., Gambadoro, A., Gao, X., Gertsenstein, M., Gomez-Segura, A., Goodwin, L.O., Heaney, J.D., Hérault, Y., de Angelis, M.H., Jiang, S.T., Justice, M.J., Kasparek, P., King, R.E., Kühn, R., Lee, H., Lee, Y.J., Liu, Z., Lloyd, K.C.K., Lorenzo, I., Mallon, A.M., McKerlie, C., Meehan, T.F., Fuentes, V.M., Newman, S., Nutter, L.M.J., Oh, G.T., Pavlovic, G., Ramirez-Solis, R., Rosen, B., Ryder, E.J., Santos, L.A., Schick, J., Seavitt, J.R., Sedlacek, R., Seisenberger, C., Seong, J.K., Skarnes, W.C., Sorg, T., Steel, K.P., Tamura, M., Tocchini-Valentini, G.P., Wang, C.K.L., Wardle-Jones, H., Wattenhofer-Donzé, M., Wells, S., Wiles, M.V., Willis, B.J., Wood, J.A., Wurst, W., Xu, Y., Teboul, L. and Murray, S.A.
Nature Genetics 53
(4): 416-419.
April 2021
Receptor combinations hone T-cell therapy.
Blankenstein, T.
Nature Biotechnology 34
(4): 389-391.
7 April 2016
Do CARs need a driver's license? Adoptive cell therapy with chimeric antigen receptor-redirected T cells caused serious adverse events.
Buening, H., Uckert, W., Cichutek, K., Hawkins, R.E. and Abken, H.
Human Gene Therapy 21
(9): 1039-1042.
September 2010
CEBPA mutations in AML: site matters.
Bullinger, L.
Blood 139
(1): 6-7.
6 January 2022
Making AML fly too close to the sun.
Bullinger, L. and Krönke, J.
Blood 143
(15): 1438-1439.
11 April 2024
Mouse models of human cancer.
Böck, B.C., Stein, U., Schmitt, C.A. and Augustin, H.G.
Cancer Research 74
(17): 4671-4675.
1 September 2014
Disentangling extrachromosomal circular DNA heterogeneity in single cells with scEC&T-seq.
Chamorro González, R. and Henssen, A.G.
Nature Genetics 55
(5): 740-741.
May 2023
What is extrachromosomal circular DNA and what does it do?
Chiu, R.W.K., Dutta, A., Henssen, A.G., Lo, Y.M.D., Mischel, P. and Regenberg, B.
Clinical Chemistry 66
(6): 754-759.
June 2020
Gentle ions for cryo-FIB milling.
Chu, X. and Kudryashev, M.
Structure 31
(10): 1147-1148.
5 October 2023
Structural insights into membrane fusion at the endoplasmic reticulum.
Daumke, O. and Praefcke, G.J.
Proceedings of the National Academy of Sciences of the United States of America 108
(6): 2175-2176.
8 February 2011
Fraternal twins at work: Structures of PLD3/4 reveal mechanism for lysosomal nucleic acid breakdown.
Daumke, O. and Damme, M.
Structure 32
(6): 645-647.
6 June 2024
SPFH protein cage - one ring to rule them all.
Daumke, O. and Lewin, G.R.
Cell Research 32
(2): 117-118.
February 2022
Mitochondrial homeostasis: How do dimers of mitofusins mediate mitochondrial fusion?
Daumke, O. and Roux, A.
Current Biology 27
(9): R353-R356.
8 May 2017
Protein-mediated membrane remodeling.
Daumke, O. and Unger, V.M.
Journal of Structural Biology 196
(1): 1-2.
October 2016
Mucosa-associated microbiota alterations in primary sclerosing cholangitis (PSC) before and after liver transplantation—who is calling the shots?
Demir, M. and Sigal, M.
Hepatobiliary Surgery and Nutrition 12
(5): 795-797.
1 October 2023
A deep dive into the circulating ctDNA cosmos to vanquish neuroblastoma.
Deubzer, H.E., Astrahantseff, K. and Lodrini, M.
Cancer Discovery 12
(12): 2727-2729.
2 December 2022
Deciphering the ubiquitin code.
Dittmar, G. and Selbach, M.
Molecular Cell 65
(5): 779-780.
2 March 2017
Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Divangahi, M., Aaby, P.r, Khader, S.A., Barreiro, L.B., Bekkering, S., Chavakis, T., van Crevel, R., Curtis, N., DiNardo, A.R., Dominguez-Andres, J., Duivenvoorden, R., Fanucchi, S., Fayad, Z., Fuchs, E., Hamon, M., Jeffrey, K.L., Khan, N., Joosten, L.A.B., Kaufmann, E., Latz, E., Matarese, G., van der Meer, J.W.M., Mhlanga, M., Moorlag, S.J.C.F.M., Mulder, W.J.M., Naik, S., Novakovic, B., O'Neill, L., Ochando, J., Ozato, K., Riksen, N.P., Sauerwein, R., Sherwood, E.R., Schlitzer, A., Schultze, J.L., Sieweke, M.H., Benn, C.S., Stunnenberg, H., Sun, J., van de Veerdonk, F.L., Weis, S., Williams, D.L., Xavier, R. and Netea, M.G.
Nature Immunology 22
(1): 2-6.
January 2021
Das Harnblasenkarzinom: interdisziplinaere Zusammenarbeit ist gefragt!
Dunst, J. and Schlag, P.M.
Onkologe 8
(9): 917.
September 2002
A cFLIP-flop switch for senolysis.
Fan, D.N.Y. and Schmitt, C.A.
Nature Cancer 3
(11): 1279-1281.
November 2022
Kommunikationstechnologie, Telematik und Robotik : Spagat zwischen Vision und Realitaet [Communication technology, telematics and robotics : balance between vision and reality].
Feussner, H. and Schlag, P.M.
Onkologe 18
(5): 386-388.
May 2012
Symptomorientierte Tumortherapie – eine interdisziplinaere Aufgabe [Symptom-oriented tumor therapy - an interdisciplinary task].
Feyer, P., Kloke, M. and Schlag, P.M.
Onkologe 13
(7): 575-576.
July 2007
The CUP-Syndrome - A quintessential challenge on interdisciplinary approach in oncology.
Flentje, M. and Schlag, P.M.
Onkologe 14
(9): 859.
September 2008
Editorial: critical issues in lymphoma management.
Fuchs, D. and Schmitt, C.A.
memo: Magazine of European Medical Oncology 12
(1): 1.
March 2019
Editorial: Monocyte heterogeneity and function.
Ginhoux, F., Mildner, A., Gautier, E.L., Schlitzer, A., Jakubzick, C., Varol, C., Bain, C. and Guermonprez, P.
Frontiers in Immunology 11
: 626725.
7 January 2021
Conditional gene expression: Intelligent designs.
Gossen, M.
Gene Therapy 13
(17): 1251-1252.
September 2006
Limited surgery in early gastric cancer.
Gretschel, S. and Schlag, P.M.
Onkologie 28
: 243-244.
1 January 2005
An intrinsic interferon program protects stem cells from viral infection.
Haas, S. and Trumpp, A.
Developmental Cell 44
(3): 279-280.
5 February 2018
Nierenzellkarzinom – Neues zu Diagnostik und Therapie? [Renal cell carcinoma - Anything new in diagnosis and therapy?].
Heinzer, H. and Schlag, P.M.
Onkologe 14
(10): 991.
October 2008
Shedding light on ecDNA behavior using CRISPR-based live-cell imaging.
Henssen, A.G.
Cancer Discovery 12
(2): 293-295.
9 February 2022
Paul Ehrlichs "magic bullets" [Paul Ehrlichs "magic bullets"].
Hochhaus, A., Schlag, P.M., Cordes, N. and Hoeffken, K.
Onkologe 19
(10): 806-808.
October 2013
Why we don't do, what we know?
Hoeffken, K., Bamberg, M. and Schlag, P.M.
Onkologe 15
(1): 84.
January 2009
„Der Onkologe“ jetzt zur Listung durch das Institute for Scientific Information (ISI) angenommen! ["The oncology" now accepted for listung through the Institute for Scientific Information (ISI)!].
Hoeffken, K., Bamberg, M. and Schlag, P.M.
Onkologe 14
(7): 657.
July 2008
Feuerwehr – Feuermelder – Brandschutz. Auf die Reihenfolge kommt es an [Firefighters Fire alarm Fire protection. The right sequence is the key].
Hoeffken, K. and Schlag, P.M.
Onkologe 14
(2): 111-112.
February 2008
Pankreaskarzinom - auf der therapeutischen Wartebank [Pancreatic cancer - on the therapeutic waiting bench].
Hopt, U. and Schlag, P.M.
Onkologe 16
(6): 555-556.
June 2010
T-cell antigen recognition: catch-as-catch-can or catch-22?
Huppa, J.B. and Schütz, G.J.
EMBO Journal 42
(7): e113507.
3 April 2023
Targeting HDAC3 in CREBBP-mutant lymphomas counterstrikes unopposed enhancer deacetylation of B-cell signaling and immune response genes.
Höpken, U.E.
Cancer Discovery 7
(1): 14-16.
January 2017
Lymphotoxin-α keeps the gate open for T-cell infiltration in cHL.
Höpken, U.E.
Blood 124
(19): 2897-2898.
6 November 2014
All roads lead to rome: triggering dendritic cell migration.
Höpken, U.E. and Lipp, M.
Immunity 20
(3): 244-246.
March 2004
Sleeping Beauty hits them all: transposon-mediated saturation mutagenesis in the mouse germline.
Izsvak, Z. and Ivics, Z.
Nature Methods 2
(10): 735-736.
October 2005
Membrane transport in multidrug resistance, development, and disease. AACR Special Conference in Cancer Research.
Jandrig, B. and Wunderlich, V.
Journal of Cancer Research and Clinical Oncology 118
(3): 238-239.
March 1992
The pathogenesis of classical Hodgkin's lymphoma: what can we learn from analyses of genomic alterations in Hodgkin and Reed-Sternberg cells?
Janz, M. and Mathas, S.
Haematologica 93
(9): 1292-1295.
September 2008
Gallengangskarzinom - Fortschritte und Grenzverschiebungen[Cholangiocarcinoma - Progress and shifting boundaries].
Jonas, S. and Schlag, P.M.
Onkologe 16
(9): 840.
September 2010
Single-cell transcriptomics enters the age of mass production.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 58
(4): 563-564.
21 May 2015
When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 45
(4): 437-438.
24 February 2012
Detouring the roadblocks in gene expression.
Junker, J.P.
Nature Reviews Molecular Cell Biology 20
(4): 197.
April 2019
Transient activated fibroblasts contribute to zebrafish heart regeneration.
Junker, J.P. and Panáková, D.
Nature Genetics 54
(8): 1076-1077.
August 2022
It's the peptide-MHC affinity, stupid.
Kammertoens, T. and Blankenstein, T.
Cancer Cell 23
(4): 429-431.
15 April 2013
"Designer cytokines" targeting the tumor vasculature - think global and act local.
Kammertoens, T., Kemna, J. and Leisegang, M.
EMBO Molecular Medicine 12
(2): e11801.
7 February 2020
Long-term structured follow-up is essential after curative cancer treatment.
Keilholz, U., Pezzutto, A., Budach, V. and Eggert, A.
Deutsches Aerzteblatt International 111
(1-2): 1-2.
6 January 2014
Translationale Melanomforschung ist nach wie vor schwer in praktische Erfolge umzumuenzen [Translational melamoma research remains difficult to transform into practical success].
Kleeberg, U.R. and Schlag, P.M.
Onkologe 15
(8): 735-736.
August 2009
Single-cell multi-omics allows functional characterization of structural variants.
Korbel, J.O. and Sanders, A.D.
Nature Biotechnology
24 November 2022
Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: its more than NF-κB!
Kreher, S., Cauchy, P., Bonifer, C. and Mathas, S.
Cytokine 72
(1): 115-117.
March 2015
Editing and investigating genomes with TALE and CRISPR/Cas systems: Genome engineering across species using TALENs.
Kuehn, R. and Wefers, B.
Methods 69
(1): 1.
15 August 2014
Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9.
Kühn, R. and Chu, V.T.
Genome Biology 16
(1): 244.
10 November 2015
Redundant regulation.
Lacadie, S.A. and Ohler, U.
Nature Ecology & Evolution 2
(3): 418-419.
March 2018
Master and commander? FoxO's role in muscle atrophy.
Langer, H.T.
Journal of Physiology 595
(14): 4593-4594.
15 July 2017
Editorial: Lineage tracing, hematopoietic stem cell and immune cell dynamics.
Lareau, C.A., Romagnani, C. and Ludwig, L.S.
Frontiers in Immunology 13
: 1062415.
18 October 2022
Human embryo models: unveiling sophisticated self-organization of stem cells during post-implantation stages.
Lin, M. and Sigal, M.
Signal Transduction and Targeted Therapy 8
(1): 419.
6 November 2023
Kolon- und Rektumkarzinom [Tumors of the colon and rectum].
Link, K.H., Anthuber, M., Gastinger, I., Heitland, W., Metzger, U., Schnider, A., Schiedeck, T., Schlag, P.M. and Staib, L.
Chirurgische Gastroenterologie 21
: 177-182.
15 June 2005
Exzessive Palliativchirurgie [Excessive palliative surgery].
Link, K.H. and Schlag, P.M.
Chirurgische Gastroenterologie 23
(4): 330-331.
December 2007
Lymphoid organogenesis: getting the green light from RORgammat.
Lipp, M. and Mueller, G.
Nature Immunology 5
(1): 12-14.
1 January 2004
Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism.
MacRae, C.A., Birchmeier, W. and Thierfelder, L.
Journal of Clinical Investigation 116
(7): 1825-1828.
July 2006
ATACing single cells with phages.
Maschmeyer, P. and Haas, S.
Molecular Cell 82
(2): 234-236.
20 January 2022
The dangers of transcription.
Mathas, S. and Misteli, T.
Cell 139
(6): 1047-1049.
11 December 2009
Magenkarzinom – Behandlung im Umbruch [Gastric cancer - treatment in transformation].
Meyer, H.J. and Schlag, P.M.
Onkologe 14
(4): 327-328.
April 2008
Krebsregister - Motor fuer Verbesserungen in der Onkologie.
Michaelis, J. and Schlag, P.M.
Onkologe 8
(1): 13.
January 2002
Ghosts in the shell: identification of microglia in the human central nervous system by P2Y12 receptor.
Mildner, A.
Neural Regeneration Research 12
(4): 570-571.
April 2017
Mapping the lung.
Mildner, A. and Yona, S.
Science 363
(6432): 1154-1155.
15 March 2019
Klinische und epidemiologische Krebsregister : Krebsregister in Deutschland – quo vadis? [Clinical and epidemiological Cancer Registers Cancer Registers in Germany - quo vadis?].
Moeslein, G., Haier, J. and Schlag, P.M.
Onkologe 19
(12): 1022-1024.
December 2013
Monocytes compensate Kupffer cell loss during bacterial infection.
Molawi, K. and Sieweke, M.H.
Immunity 42
(1): 10-12.
20 January 2015
Editorial: Modulation of human immune parameters by anticancer therapies, volume II.
Na, I.K., Sack, U. and Sánchez-Ramón, S.
Frontiers in Immunology 14
: 1249099.
26 July 2023
Building interdisciplinarity in research on gene therapy.
Niewoehner, J.D. and Tannert, C.
Gene Therapy: Prospective Technology assessment in its societal context
: xiii-xix.
2006
First person - Marcel Nowak and Benjamin Suenkel.
Nowak, M. and Suenkel, B.
Journal of Cell Science 132
(17): jcs237297.
September 2019
Recapitulating the tumor microenvironment in a dish, one cell type at a time.
Ostendorf, B.N.
Cell Reports Methods 4
(6): 100800.
17 June 2024
The thirteenth meeting of the European Association for Cancer Research, Berlin, Germany, 25. - 28. September, 1994.
Pasternak, G. and Wunderlich, V.
Journal of Molecular Medicine 73
(3): 153-155.
March 1995
Future trends and challenges in pathogenomics.
Pompe, S., Simon, J., Wiedemann, P.M. and Tannert, C.
EMBO Reports 6
(7): 600-605.
July 2005
Therapy-induced senescence: opportunities to improve anticancer therapy.
Prasanna, P.G., Citrin, D.E., Hildesheim, J., Ahmed, M.M., Venkatachalam, S., Riscuta, G., Xi, D., Zheng, G., van Deursen, J., Goronzy, J., Kron, S.J., Anscher, M.S., Sharpless, N.E., Campisi, J., Brown, S.L., Niedernhofer, L.J., O'Loghlen, A., Georgakilas, A.G., Paris, F., Gius, D., Gewirtz, D.A., Schmitt, C.A., Abazeed, M.E., Kirkland, J.L., Richmond, A., Romesser, P.B., Lowe, S.W., Gil, J., Mendonca, M.S., Burma, S., Zhou, D. and Coleman, C.N.
Journal of the National Cancer Institute 113
(10): 1285-1298.
October 2021
Cellular hierarchies predict drug response in acute myeloid leukemia.
Raffel, S., Velten, L. and Haas, S.
Cancer Cell 40
(9): 917-919.
12 September 2022
The DNA deamination model of somatic antibody diversification.
Rajewsky, K.
Journal of Immunology 194
(5): 2041-2042.
1 March 2015
Michael S. Neuberger 1953-2013.
Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 111
(8): 2862-2863.
25 February 2014
The advent and rise of monoclonal antibodies.
Rajewsky, K.
Nature 575
(7781): 47-49.
November 2019
A CD205-directed antibody drug conjugate - lymphoma precision oncology or sophisticated chemotherapy?
Rieke, D.T. and Keller, U.
Haematologica 105
(11): 2504-2506.
1 November 2020
Rektumkarzinom - ein Musterbeispiel fuer Interdisziplinaritaet [Rectal carcinoma - a classic example of interdisciplinarity].
Roedel, C. and Schlag, P.M.
Onkologe 16
(8): 738-740.
August 2010
Making tubes: Step by step.
Rosario, M. and Birchmeier, W.
Developmental Cell 7
(1): 3-5.
1 July 2004
Editorial: Modulation of human immune parameters by anticancer therapies.
Sack, U., Tarnok, A., Preijers, F., Köhl, U. and Na, I.K.
Frontiers in Immunology 11
: 621556.
2 December 2020
Burkitt lymphomagenesis linked to MYC plus PI3K in germinal center B cells.
Sander, S. and Rajewsky, K.
Oncotarget 3
(10): 1066-1067.
28 October 2012
Eosinophils and mast cells: a lineage apart.
Sarrazin, S. and Sieweke, M.H.
Nature Immunology 17
(6): 609-611.
19 May 2016
"Curt Meyer-Gedaechtnispreis" Forschungspreis der Berliner Krebsgesellschaft 2010 ausgeschrieben.
Schlag, P.M.
Onkologe 15
(11): 1100.
November 2009
Back to the future? Neue Aspekte in der Therapie der peritonealen Karzinose.
Schlag, P.M.
Chirurg 78
(12): 1083-1084.
December 2007
Targeted therapies - mehr als nur ein bahnbrechendes therapeutisches Prinzip.
Schlag, P.M.
Onkologe 13
(1): 7.
January 2007
Das Modell der Adenom-Karzinom-Sequenz - ein Zwischenruf. Kommentar zu den Arbeiten von F. Stelzner.
Schlag, P.M.
Chirurg 77
(11): 1061-1062.
November 2006
Ex vivo sentinel lymph node study for rectal adenocarcinoma: Preliminary study - Invited commentary.
Schlag, P.M.
World Journal of Surgery 29
(9): 1171-1171.
25 August 2005
Do we need surgical oncologists?
Schlag, P.M.
Onkologie 25
(4): 306-307.
August 2002
On the threshold of a new medicine.
Schlag, P.M.
Onkologie 20
: 8.
1 January 1997
Zwischen Hoffen und Bangen [Between hope and fear].
Schlag, P.M. and Bamberg, M.
Onkologe 16
(11): 11038-1040.
November 2010
Seltene Tumoren - Vom Seltenen zum Generellen [Rare tumours - From rare to general].
Schlag, P.M., Bamberg, M. and Hoeffken, K.
Onkologe 15
(3): 209-210.
March 2009
COVID-19: new disease mechanism is simultaneously a therapeutic target.
Schmitt, C.A.
memo: Magazine of European Medical Oncology 15
(2): 100-101.
June 2022
UnSASPing senescence: unmasking tumor suppression?
Schmitt, C.A.
Cancer Cell 34
(1): 6-8.
9 July 2018
The persistent dynamic secrets of senescence.
Schmitt, C.A.
Nature Cell Biology 18
(9): 913-915.
September 2016
Versorgungsforschung – Notwendigkeit und Chancen [Health service research - necessity and opportunity].
Schmitz, S. and Schlag, P.M.
Onkologe 18
(2): 102-104.
February 2012
The liberation of women from the scourge of cervical cancer.
Schneider, A. and Schlag, P.M.
Onkologe 18
(1): 6-8.
January 2012
Weichteilsarkome [Soft part arkome].
Schuette, J. and Schlag, P.M.
Onkologe 15
(4): 351.
April 2009
Eine Tuer wird aufgestossen.
Schuette, J. and Schlag, P.M.
Onkologe 8
(4): 319.
April 2002
NEMHESYS - European perspective on the implementation of next-generation sequencing into clinical diagnostics.
Serramito-Gómez, I., Clarke, K.M., Rodríguez-Vicente, A.E., McGimpsey, J.E., Abáigar, M., Díez, C.B., Benito, R., Bullinger, L., Mills, K.I. and Hernández Rivas, J.M.
HemaSphere 5
(3): e541.
March 2021
Primary malignant tumors of the liver.
Settmacher, U. and Schlag, P.M.
Onkologe 18
(7): 570-572.
July 2012
Tranplantation und Onkologie [Transplantation and oncology].
Settmacher, U. and Schlag, P.M.
Onkologe 15
(6): 555-556.
June 2009
Waddington's Valleys and Captain Cook's Islands.
Sieweke, M.H.
Cell Stem Cell 16
(1): 7-8.
8 January 2015
Wie das Immunsystem SARS-CoV-2 den Weg ebnet [How the immune system paves the way for SARS-CoV-2].
Sigal, M.
Hygiene und Medizin 46
(3): 22-23.
2021
A TORway to osteolytic disease.
Smink, J.J. and Leutz, A.
Cell Cycle 11
(4): 637-638.
15 February 2012
Systematic perturbation of chromatin factors identifies regulatory networks during healthy and malignant hematopoiesis.
Solé-Boldo, L. and Haas, S.
Nature Genetics 55
(9): 1430-1431.
September 2023
Lectins in the endoplasmic reticulum: the sweet side of protein quality control.
Sommer, T. and Gauss, R.
Developmental Cell 14
(4): 463-464.
15 April 2008
San1p, checking up on nuclear proteins.
Sommer, T. and Hirsch, C.
Cell 120
(6): 734-736.
1 January 2005
Pardon me - No access without ubiquitin.
Sommer, T. and Jarosch, E.
Developmental Cell 8
(1): 4-5.
1 January 2005
Rsp5/Nedd4 clears cells of heat-damaged proteins.
Sommer, T., Weber, A. and Jarosch, E.
Nature Cell Biology 16
(12): 1130-1132.
1 December 2014
The ubiquitin-proteasome-system.
Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1843
(1): 1.
January 2014
Nikolai V. Timofeeff-Ressovsky and the Campus Berlin-Buch.
Sommer, T.
Genetics, Evolution and Radiation
: ix-xi.
2016
Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M., Besser, D. and Benitah, S.A.
EMBO Reports 13
(1): 9-11.
January 2012
Preface.
Stein, U.S.
Methods in Molecular Biology 2294
: v.
2021
Laser microdissection of a colon cancer specimen with subsequent RNA isolation, mRNA amplification and microarray hybridization.
Stoinski-Bungs, E., Seeger, S., Kemmner, W., Scheinert, P. and Krupp, G.
Nature Methods Application Notes
: an10-an11.
1 January 2006
Editorial: Mitochondria as a hub in cellular signaling.
Stoolman, J.S., Porcelli, A.M. and Martínez-Reyes, I.
Frontiers in Cell and Developmental Biology 10
: 981464.
15 August 2022
UroFors: Konstituierung eines Interessensverbundes fuer Naturwissenschaftler in der urologischen Forschung [UroFors: establishment of an interest group for natural scientists in urological research].
Stope, M.B., Dansranjavin, T., Erb, H., Erdmann, K., Fendler, A., Hoelters, S., Juengel, E., Nitschke, K., Salomo, K., Seidel, P., Skowron, M.A., Wach, S. and Becker, C.
Urologe 56
(4): 515-518.
April 2017
Unrestricted cell cycling and cancer.
Strauss, M., Lukas, J. and Bartek, J.
Nature Medicine 1
(12): 1245-1246.
December 1995
EU-LIFE charter of independent life science research institutes.
Superti-Furga, G., Agostinho, M., Bury, J., Cook, S., Durinx, C., Ender, A., van Luenen, H., Lund, A.H., Medema, R.H., Miączyńska, M., Nickel, D., Pelicci, P.G., Puisieux, A., Ripatti, S., Sander, M., Schubeler, D., Serrano, L., Sommer, T., Sonne-Hansen, K., Tomančák, P., Vives, J., Vontas, J. and Bettencourt-Dias, M.
FEBS Letters 598
(7): 719-724.
April 2024
Thou shalt not clone. An ethical argument against the reproductive cloning of humans.
Tannert, C.
EMBO Reports 7
(3): 238-240.
1 March 2006
The ethics of uncertainty. In the light of possible dangers, research becomes a moral duty.
Tannert, C., Elvers, H.D. and Jandrig, B.
EMBO Reports 8
(10): 892-896.
1 October 2007
Invasion and metastasis: stem cells, screens and survival. Conference on Invasion and Metastasis.
Tapon, N. and Ziebold, U.
EMBO Reports 9
(11): 1078-1083.
1 November 2008
Venetoclax resistance and acquired mutations in chronic lymphocytic leukemia.
Tausch, E., Close, W., Dolnik, A., Bloehdorn, J., Chyla, B., Bullinger, L., Döhner, H., Mertens, D. and Stilgenbauer, S.
Haematologica 104
(9): e434-e437.
September 2019
CT-gesteuerte bronchoskopische Punktion zur Diagnosesicherung einer hilaeren Raumforderung [CT-controlled bronchoscopic puncture in diagnostic verification of hilar space occupying lesion].
Teichgraeber, U.K., Gebauer, B. and Benter, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 175
: 857-858.
1 June 2003
Acute myeloid leukemia: does sex matter?
Tettero, J.M., Cloos, J. and Bullinger, L.
Leukemia 38
(11): 2329-2331.
November 2024
Mapping the complexity of transcription control in higher eukaryotes.
Tomancak, P. and Ohler, U.
Genome Biology 11
(4): 115.
30 April 2010
Cancer stem cells: The adventurous journey from hematopoietic to leukemic stem cells.
Trumpp, A. and Haas, S.
Cell 185
(8): 1266-1270.
14 April 2022
How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates.
Turco, E., Witt, M., Abert, C., Bock-Bierbaum, T., Su, M.Y., Trapannone, R., Sztacho, M., Danieli, A., Shi, X., Zaffagnini, G., Gamper, A., Schuschnig, M., Fracchiolla, D., Bernklau, D., Romanov, J., Hartl, M., Hurley, J.H., Daumke, O. and Martens, S.
Autophagy 15
(8): 1475-1477.
August 2019
Time-keeping and decision-making in living cells: Part II.
Tyson, J.J., Csikasz-Nagy, A., Gonze, D., Kim, J.K., Santos, S. and Wolf, J.
Interface Focus 12
(4): 20220024.
10 June 2022
Time-keeping and decision-making in living cells: Part I.
Tyson, J.J., Csikasz-Nagy, A., Gonze, D., Kim, J.K., Santos, S. and Wolf, J.
Interface Focus 12
(3): 20220011.
6 June 2022
Uncovering a unique role for DNA methylation in hematopoietic and leukemic stem cells.
Vockentanz, L., Broeske, A.M. and Rosenbauer, F.
Cell Cycle 9
(4): 640-641.
February 2010
Editorial: The MACC1 network in cancer.
Walther, W., Siegel, F. and Stein, U.
Frontiers in Oncology 13
: 1343812.
5 July 2024
A novel allele for inducible Cre expression in germinal center B cells.
Weber, T., Seagal, J., Winkler, W., Wirtz, T., Chu, V.T. and Rajewsky, K.
European Journal of Immunology 49
(1): 192-194.
January 2019
Kolonkarzinom – Es bleibt noch viel zu tun [Colorectal carcinoma - there is still a lot to be done].
Weitz, J. and Schlag, P.M.
Onkologe 15
(12): 1179.
December 2009
The future of stem-cell research in Germany.
Wiedemann, P.M., Simon, J., Schicktanz, S. and Tannert, C.
EMBO Reports 5
(10): 927-931.
1 October 2004
Viel Bewegung in der interdisziplinaeren Therapie des Nierenzellkarzinoms [A lot of movement in the interdisciplinary treatment of renal cell carcinoma].
Wiegel, T. and Schlag, P.M.
Onkologe 16
(2): 119-120.
February 2010
Adoptive T-cell therapy to treat liver cancer: Is the liver microenvironment key?
Willimsky, G., Protzer, U., Knolle, P. and Heikenwalder, M.
Oncotarget 4
(8): 1117-1118.
August 2013
Harnblasenkarzinom: Stetiger Behandlungsfortschritt als Antwort auf eine zunehmende Erkrankungsinzidenz
[Carcinoma of the urinary bladder: steady progress in treatment as response to an increasing disease incidence].
Wirth, M. and Schlag, P.M.
Onkologe 13
(12): 1057.
December 2007
A hypoxia-epigenetics axis drives EMT in pancreatic cancer.
Wirth, M. and Schneider, G.
Cancer Research 84
(11): 1739-1741.
1 June 2024
Death gives birth to life: the essential role of the ubiquitin-proteasome system in biology.
Wolf, D.H., Sommer, T. and Hilt, W.
Biochimica et Biophysica Acta - Molecular Cell Research 1695
(1-3): 1-2.
1 January 2004
JMM - Past and Present. Chromosomes and cancer: Theodor Boveri's predictions 100 years later.
Wunderlich, V.
Journal of Molecular Medicine 80
(9): 545-548.
September 2002
High-mobility-group proteins and cancer - an emerging link.
Wunderlich, V. and Boettger, M.
Journal of Cancer Research and Clinical Oncology 123
(3): 133-140.
March 1997
What do you most hope spatial molecular profiling will help us understand? Part 2.
Yanai, I., Fertig, E.J., Li, M., Coscia, F., Klughammer, J., Nie, Q., Chen, J. and Coskun, A.F.
Cell Systems 14
(7): 543-546.
19 July 2023
Good things come in threes.
Yona, S. and Mildner, A.
Science Immunology 3
(30): eaav5545.
7 December 2018
The importance of developing therapies targeting the biological spectrum of metastatic disease.
Zijlstra, A., Von Lersner, A., Yu, D., Borrello, L., Oudin, M., Kang, Y., Sahai, E., Fingleton, B., Stein, U., Cox, T.R., Price, J.T., Kato, Y., Welm, A.L. and Aguirre-Ghiso, J.A.
Clinical and Experimental Metastasis 36
(4): 305-309.
August 2019
Trained macrophages support hygiene hypothesis.
de Laval, B. and Sieweke, M.H.
Nature Immunology 18
(12): 1279-1280.
16 November 2017
Comment
Taking out the trash: How misfolded proteins are removed from the endoplasmic reticulum.
Brodsky, J.L., Engelman, D.M., Hendershot, L.M., Piana-Agostinetti, S. and Sommer, T.
Faculty Reviews 11
: 29.
5 October 2022
IDH2 inhibition: another piece to the puzzle.
Bullinger, L.
Blood 133
(7): 625-626.
14 February 2019
Turning science into cover art.
Dauben, H., Matic, I., Kidmose, R.T., Pedersen, B.P., Saha, T., Di Virgilio, M. and Sung, J.H.
Trends in Biochemical Sciences 48
(12): 1009-1011.
December 2023
Wie weiblich ist die Onkologie in Deutschland? [How feminine is oncology in Germany?].
Fehm, T., Behrens, B., Friebe, V., Krawczyk, N., Bleckmann, A., Höpken, U., Wardelmann, E., Heinrich, K., Duda, A., Gögel, S., Wesselmann, S., Nothacker, M., Schmalfeldt, B. and Hasenburg, A.
Forum 39
: 212–216.
June 2024
Marsupial genomes reveal how a skin membrane for gliding evolved.
Lupiáñez, D.G.
Nature 629
(8010): 43-44.
2 May 2024
Cellular atlases are unlocking the mysteries of the human body.
Yanai, I., Haas, S., Lippert, C. and Kretzmer, H.
Nature 635
(8039): 553-555.
November 2024
Preprint
Transcript-specific enrichment enables profiling rare cell states via scRNA-seq.
Abay, T., Stickels, R.R., Takizawa, M.T., Nalbant, B.N., Hsieh, Y.H., Hwang, S., Snopkowski, C., Yu, K.K.H., Abou-Mrad, Z., Tabar, V., Ludwig, L.S., Chaligne, R., Satpathy, A.T. and Lareau, C.A.
bioRxiv
: 2024.03.27.587039.
27 March 2024
Determinants of SARS-CoV-2 receptor gene expression in upper and lower airways.
Aliee, H., Massip, F., Qi, C., de Biase, M.S., van Nijnatten, J.L., Kersten, E.T.G., Kermani, N.Z., Khuder, B., Vonk, J.M., Vermeulen, R.C.H., Neighbors, M., Tew, G.W., Grimbaldeston, M., Ten Hacken, N.H.T., Hu, S., Guo, Y., Zhang, X., Sun, K., Hiemstra, P.S., Ponder, B.A., Makela, M.J., Malmstrom, K., Rintoul, R.C., Reyfman, P.A., Theis, F.J., Brandsma, C.A., Adcock, I., Timens, W., Xu, C.J., van den Berge, M., Schwarz, R.F., Koppelman, G.H., Nawijn, M.C. and Faiz, A.
medRxiv
: 2020.08.31.20169946.
2 September 2020
Targeted disruption of linkage-specific ubiquitylation reveals a key role of K29-linked ubiquitylation in epigenome integrity.
Arroyo-Gomez, J., Wang, J., Guérillon, C., Isaakova, E., Reverón-Gómez, N., Koutrouli, M., Rahmanto, A.S., Mitrofanov, K., Ingham, A., Schovsbo, S., Weischenfeldt, K., Coscia, F., Typas, D., Völker-Albert, M., Solis, V., Jensen, L.J., Groth, A., Mund, A., Beli, P., Shearer, R.F. and Mailand, N.
bioRxiv
: 2024.10.29.620783.
2 November 2024
Co-activation of NF-κB and MYC renders cancer cells addicted to IL6 for survival and phenotypic stability.
Barbosa, R.R., Xu, A.Q., D'Andrea, D., Copley, F., Patel, H., Chakravarty, P., Clear, A., Calaminici, M., Janz, M., Zhang, B., Schmidt-Supprian, M., Wang, J., Gribben, J.G., Tooze, R., Fitzgibbon, J., Franzoso, G., Rajewsky, K. and Calado, D.P.
bioRxiv
: 2020.04.12.038414.
13 April 2020
CD40 provides immune privilege to the bone marrow hematopoietic niche.
Bassani, B., Gulino, A., Portararo, P., Botti, L., Cappetti, B., Chiodoni, C., Bolli, N., Ciciarello, M., Joehrens, K., Anagnostopoulos, I., Na, I.K., Curti, A., Tripodo, C., Colombo, M.P. and Sangaletti, S.
bioRxiv
: 2020.08.10.243691.
10 August 2020
Establishment of kidney cancer organoid cultures.
Bauer, D., Birchmeier, W. and Fendler, A.
Research Square
: rs.3.pex-911.
12 May 2020
LoopDetect: comprehensive feedback loop detection in ordinary differential equation models.
Baum, K. and Wolf, J.
bioRxiv
: 2020.11.15.383703.
17 November 2020
Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated transcriptome in human cells.
Boehm, V., Wallmeroth, D., Wulf, P.O., Teixeira Alves, L.G., Popp, O., Riedel, M., Wyler, E., Franitza, M., Gerbracht, J.V., Becker, K., Polkovnychenko, K., Del Giudice, S., Benlasfer, N., Mertins, P., Landthaler, M. and Gehring, N.H.
bioRxiv
: 2024.03.04.583328.
8 March 2024
Crowdfunded whole-genome sequencing of the celebrity cat Lil BUB identifies causal mutations for her osteopetrosis and polydactyly.
Bridavsky, M., Kuhl, H., Woodruf, A., Kornak, U., Timmermann, B., Mages, N., Lupiáñez, D.G., Symmons, O. and Ibrahim, D.M.
bioRxiv
: 556761.
22 February 2019
Autophagy limits inflammatory gene expression through targeting of nuclear p65/RelA by LC3 and p62 for lysosomal degradation.
Brischetto, C., Mucka, P., Kaergel, E. and Scheidereit, C.
bioRxiv
: 2022.11.02.514846.
2 November 2022
Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types.
Calabrese, C., Davidson, N.R., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., Soulette, C.M., Urban, L., Demircioğlu, D., Greger, L., Li, S., Liu, D., Perry, M.D., Xiang, L., Zhang, F., Zhang, J., Bailey, P., Erkek, S., Hoadley, K.A., Hou, Y., Kilpinen, H., Korbel, J.O., Marin, M.G., Markowski, J., Nandi, T., Pan-Hammarström, Q., Pedamallu, C.S., Siebert, R., Stark, S.G., Su, H., Tan, P., Waszak, S.M., Yung, C., Zhu, S., Awadalla, P., Creighton, C.J., Meyerson, M., Ouellette, B.F.F., Wu, K., Yang, H., Brazma, A., Brooks, A.N., Göke, J., Rätsch, G., Schwarz, R.F., Stegle, O. and Zhang, Z.
bioRxiv
: 183889.
12 March 2018
Assessing the gene regulatory landscape in 1,188 human tumors.
Calabrese, C., Lehmann, K.V., Urban, L., Liu, F., Erkek, S., Fonseca, N., Kahles, A., Kilpinen-Barrett, L.H., Markowski, J., Waszak, S., Korbel, J., Zhang, Z., Brazma, A., Raetsch, G., Schwarz, R. and Stegle, O.
bioRxiv
: 225441.
29 November 2017
Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data.
Calviello, L., Sydow, D., Harnett, D. and Ohler, U.
bioRxiv
: 601468.
8 April 2019
Wnt11/Fzd7 signaling compartmentalizes AKAP2/PKA to regulate L-type Ca(2+) channel.
Csalyi, K.D., Rharass, T., Schulz, M., Phan, M.H.Q., Wakula, P., Mhatre, K.N., Plotnick, D., Werdich, A.A., Zauber, H., Sury, M.D., Selbach, M., Heinzel, F.R., Klussmann, E. and Panakova, D.
bioRxiv
: 741637.
20 August 2019
High-quality peptide evidence for annotating non-canonical open reading frames as human proteins.
Deutsch, Eric W, Kok, Leron W, Mudge, Jonathan M, Ruiz-Orera, J., Fierro-Monti, Ivo, Sun, Zhi, Abelin, Jennifer G, Alba, M Mar, Aspden, Julie L, Bazzini, Ariel A, Bruford, Elspeth, Brunet, Marie A, Calviello, L., Carr, Steven A, Carvunis, Anne-Ruxandra, Chothani, Sonia, Clauwaert, Jim, Dean, Kellie, Faridi, Pouya, Frankish, Adam, Hubner, N., Ingolia, Nicholas, Magrane, Michele, Martin, Maria Jesus, Martinez, Thomas F, Menschaert, Gerben, Ohler, U., Orchard, Sandra, Rackham, Owen, Roucou, Xavier, Slavoff, Sarah A, Valen, Eivind, Wacholder, Aaron C, Weissman, Jonathan S., Wu, Wei, Xie, Zhi, Choudhary, Jyoti, Bassani-Sternberg, Michal, Vizcaino, Juan Antonio, Ternette, Nicola, Moritz, Robert L., Prensner, John and van Heesch, S.
bioRxiv
: 2024.09.09.612016.
9 September 2024
HMGXB4 targets Sleeping Beauty transposition to vertebrate germinal stem sells.
Devaraj, A., Singh, M., Narayanavari, S., Yong, G., Wang, J., Wang, J., Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z., Grzela, D., Raskó, T., Selbach, M., Ivics, Z. and Izsvák, Z.
bioRxiv
: 2020.06.15.145656.
15 June 2020
Targeted perturb-seq reveals EGR1 and FOS as key regulators of the transcriptional RAF-MAPK response.
El Kassem, G., Sieber, A., Klinger, B., Uhlitz, F., Steinbrecht, D., van Bentum, M., Hillmer, J., von Schlichting, J., Schäfer, R., Blüthgen, N. and Boettcher, M.
bioRxiv
: 2024.01.13.575500.
15 January 2024
Gene-edited primary muscle stem cells rescue dysferlin-deficient muscular dystrophy.
Escobar Fernandez, H., Di Francescantonio, S., Marg, A., Zhogov, A., Krishna, S., Metzler, E., Petkova, M., Daumke, O., Kühn, R. and Spuler, S.
bioRxiv
: 2024.02.12.579813.
12 February 2024
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in severe COVID-19.
Essex, M., Pascual-Leone, B.M., Löber, U., Kuhring, M., Zhang, B., Bruening, U., Fritsche-Guenther, R., Krzanowski, M., Vernengo, F.F., Brumhard, S., Röwekamp, I., Bielecka, A.A., Lesker, T.R., Wyler, E., Landthaler, M., Mantei, A., Meisel, C., Caesar, S., Thiebeault, C., Corman, V., Marko, L., Suttorp, N., Strowig, T., Kurth, F., Sander, L.E., Li, Y., Kirwan, J.A., Forslund, S.K. and Opitz, B.
bioRxiv
: 2022.12.02.518860.
2 December 2022
In vivo sequential mutagenesis in germinal center B cells using a dual-recombinase approach: FOXO1 re-expression upon FOXO1 knockout rescues class switch recombination.
Farré Díaz, C., Kabrani, E., Winkler, W., Salomon, C., Wunderlich, F.T., Janz, M. and Rajewsky, K.
bioRxiv
: 2024.05.17.592915.
22 May 2024
One gene - two proteins: the C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria.
Fasciani, I., Petragnano, F., Wang, Z., Edwards, R., Telugu, N., Pietrantoni, I., Zauber, H., Rossi, M., Zabel, U., Grieben, M., Terzenidou, M.E., Di Gregorio, J., Pellegrini, C., Santini, S., Taddei, A.R., Poehl, B., Aringhieri, S., Aloisi, G., Marampon, F., Roman, A., Diecke, S., Flati, V., Giorgi, F., Amicarelli, F., Tobin, A.B., Scarselli, M., Tokatlidis, K., Lohse, M.J., Maggio, R. and Annibale, P.
bioRxiv
: 2021.04.13.438299.
26 February 2022
IGF1R is protective in pneumococcal pneumonia.
Felten, M., Teixeira Alves, L.G., Letsiou, E., Arnedo, E.A., Piñeiro-Hermida, S., López, I.P., Dietert, K., Firsching, T., Gruber, A.D., Fatykhova, D., Hocke, A., Lingscheid, T., Lienau, J., Rohde, G., Pichel, J.G. and Witzenrath, M.
bioRxiv
: 2024.09.11.612370.
11 September 2024
Open Source ImmGen: network perspective on metabolic diversity among mononuclear phagocytes.
Gainullina, A., Huang, L.H., Todorov, H., Kim, K., Yng, L.S., Kent, A., Jia, B., Seddu, K., Krchma, K., Wu, J., Crozat, K., Tomasello, E., Narang, V., Dress, R., See, P., Scott, C., Gibbings, S., Bajpai, G., Desai, J.V., Maier, B., This, S., Wang, P., Aguilar, S.V., Poupel, L., Dussaud, S., Zhou, T.A., Angeli, V., Blander, J.M., Choi, K., Dalod, M., Dzhagalov, I., Gautier, E.L., Jakubzick, C., Lavine, K., Lionakis, M.S., Paidassi, H., Sieweke, M.H., Ginhoux, Fl., Guilliams, M., Benoist, C., Merad, M., Randolph, G.J., Sergushichev, A. and Artyomov, M.N.
bioRxiv
: 2020.07.15.204388.
16 July 2020
Mechanistic basis for motor-driven membrane constriction by dynamin.
Ganichkin, O., Vancraenenbroeck, R., Rosenblum, G., Hofmann, H., Mikhailov, A.S., Daumke, O. and Noel, J.K.
bioRxiv
: 2020.09.10.289546.
11 September 2020
Exploiting a PAX3-FOXO1-induced synthetic lethal ATR dependency for rhabdomyosarcoma therapy.
García, H.D., Bei, Y., von Stebut, J., Ibáñez, G., Imami, K., Gürgen, D., Rolff, J., Helmsauer, K., Timme, N., Bardinet, V., Chamorro González, R., MacArthur, I.C., Pusch, F.F., Chen, C.Y., Schulz, J., Wengner, A.M., Furth, C., Lala, B., Eggert, A., Seifert, G., Hundsoerfer, P., Kirchner, M., Mertins, P., Selbach, M., Lissat, A., Schulte, J.H., Haase, K., Scheer, M., Ortiz, M.V. and Henssen, A.G.
bioRxiv
: 2020.12.04.411413.
2020
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II at pro-differentiation genes.
Garipler, G., Lu, C., Morrissey, A., Lopez-Zepeda, L.S., Vidal, S.E., Aydin, B., Stadtfeld, M., Ohler, U., Mahony, S., Sanjana, N.E. and Mazzoni, E.O.
bioRxiv
: 2020.11.23.391771.
23 November 2020
Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia.
Gilioli, D., Fusco, S., Tavella, T., Giannetti, K., Conti, A., Santoro, A., Carsana, E., Beretta, S., Schönlein, M., Gambacorta, V., Aletti, F.M., Carraba, M.G., Bonini, C., Ciceri, F., Merelli, I., Vago, L., Schmitt, C.A. and Di Micco, R.
bioRxiv
: 2022.11.17.515658.
17 November 2022
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy.
Grunewald, L., Andersch, L., Helmsauer, K., Schwiebert, S., Klaus, A., Henssen, A.G., Straka, T., Lodrini, M., Wicha, S.G., Fuchs, S., Hertwig, F., Westermann, F., Vitali, A., Caramel, C., Büchel, G., Eilers, M., Astrahantseff, K., Eggert, A., Höpken, U.E., Schulte, J.H., Blankenstein, T., Anders, K. and Künkele, A.
bioRxiv
: 2024.01.27.576592.
29 January 2024
Timed global reorganization of protein synthesis during neocortex neurogenesis at codon resolution.
Harnett, D., Ambrozkiewicz, M.C., Zinnall, U., Borisova, E., Rusanova, A., Dannenberg, R., Imami, K., Münster-Wandowski, A., Fauler, B., Mielke, T., Selbach, M., Landthaler, M., Spahn, C.M.T., Tarabykin, V., Ohler, U. and Kraushar, M.L.
bioRxiv
: 2021.06.23.449626.
24 June 2021
Insights, opportunities and challenges provided by large cell atlases.
Hemberg, M., Marini, F., Ghazanfar, S., Al Ajami, A., Abassi, N., Anchang, B., Benayoun, B.A., Cao, Y., Chen, K., Cuesta-Astroz, Y., DeBruine, Z., Dendrou, K.A., De Vlaminck, I., Imkeller, K., Korsunsky, I., Lederer, A.R., Meysman, P., Miller, C., Mullan, K., Ohler, U., Patikas, N., Schuck, N., Siu, J.H.Y., Triche, T.J., Tsankov, A., van der Laan, S.W., Yajima, M., Yang, J., Zanini, F. and Jelic, I.
arXiv
: 2408.06563.
13 August 2024
Extensive folding variability between homologous chromosomes in mammalian cells.
Irastorza-Azcarate, I., Kukalev, A., Kempfer, R., Thieme, C.J., Mastrobuoni, G., Markowski, J., Loof, G., Sparks, T.M., Brookes, E., Natarajan, K.N., Sauer, S., Fisher, A.G., Nicodemi, M., Ren, B., Schwarz, R.F., Kempa, S. and Pombo, A.
bioRxiv
: 2024.05.08.591087.
10 May 2024
Massively parallel clonal analysis using CRISPR/Cas9 induced genetic scars.
Junker, J.P., Spanjaard, B., Peterson-Maduro, J., Alemany, A., Hu, B., Florescu, M. and van Oudenaarden, A.
bioRxiv
: 056499.
4 January 2017
Single cell RNA-sequencing-based analysis of CD4(+) T-cell subset-specific susceptibility to transcriptional modulation by HIV-1 latency-reversing agents.
Kazmierski, J., Postmus, D., Wyler, E., Fischer, C., Jansen, J., Meixenberger, K., Vitcetz, S.N., Sohn, M., Sauer, S., Bannert, N., Landthaler, M. and Goffinet, C.
bioRxiv
: 2020.05.04.075119.
5 May 2020
Principles of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancers.
Lange, J.T., Chen, C.Y., Pichugin, Y., Xie, L., Tang, J., Hung, K.L., Yost, K.E., Shi, Q., Erb, M.L., Rajkumar, U., Wu, S., Swanton, C., Liu, Z., Huang, W., Chang, H.Y., Bafna, V., Henssen, A.G., Werner, B. and Mischel, P.S.
bioRxiv
: 10.1101/2021.06.11.447968.
11 June 2021
Artifacts in single-cell mitochondrial DNA mutation analyses misinform phylogenetic inference.
Lareau, C.A., Chapman, M.S., Penter, L., Nawy, T., Pe’er, D. and Ludwig, L.S.
bioRxiv
: 2024.07.28.605517v2.
5 October 2024
SARS-CoV-2 neutralization and protection of hamsters via nasal administration of a humanized neutralizing antibody.
Lebedin, M., Petrovsky, N., Tabynov, K., Tabynov, K. and Lebedin, Y.
bioRxiv
: 2024.07.08.602557.
8 July 2024
Morphine alleviates pain after heart cryoinjury in zebrafish without impeding regeneration.
Lelek, S., Simões, M., Hu, B., Alameldeen, A.M.A., Czajkowski, M.T., Meyer, A.M., Ferrara, F., Junker, J.P. and Panáková, D.
bioRxiv
: 2020.10.01.322560.
2 October 2020
Denoising, deblurring, and optical deconvolution for cryo-ET and light microscopy with a physics-informed deep neural network DeBCR.
Li, R., Yushkevich, A., Chu, X., Kudryashev, M. and Yakimovich, A.
bioRxiv
: 2024.07.12.603278.
16 July 2024
N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers.
Lueg, G.A., Faronato, M., Gorelik, A., Grocin, A.G., Caamano-Gutierrez, E., Falciani, F., Solari, R., Carr, R., Bell, A.S., Bartlett, E., Hutton, J.A., Llorian-Sopena, M., Chakravarty, P., Brzezicha, B., Janz, M., Garnett, M.J., Calado, D.P. and Tate, E.W.
bioRxiv
: 2021.03.20.436222.
20 March 2021
The little skate genome and the evolutionary emergence of wing-like fin appendages.
Marletaz, F., de la Calle-Mustienes, E., Acemel, R.D., Nakamura, T., Paliou, C., Naranjo, S., Martinez-Garcia, P.M., Cases, I., Sleight, V.A., Hirschberger, C., Marcet-Houben, M., Navon, D., Andrescavage, A., Skvortsova, K., Duckett, P.E., Gonzalez-Rajal, A., Bogdanovic, O., Gibcus, J.H., Yang, L., Gallardo-Fuentes, L., Sospedra, I., Lopez-Rios, J., Darbellay, F., Visel, A., Dekker, J., Shubin, N., Gabaldon, T., Tena, J.J., Lupianez, D.G., Rokhsar, D.S. and Gomez-Skarmeta, J.L.
bioRxiv
: 2022.03.21.485123.
22 March 2022
Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer.
McPherson, A.W., Vázquez-Garcia, I., Myers, M.A., Zatzman, M., Al-Rawi, D.H., Weiner, A.C., Freeman, S.S., Mohibullah, N., Satas, G., Williams, M.J., Ceglia, N., Zhang, A.W., Li, J., Lim, J.L.P., Wu, M., Choi, S., Havasov, E., Grewal, D., Shi, H., Kim, M., Schwarz, R.F., Kaufmann (Ohler), T.L., Dinh, K.N., Uhlitz, F., Tran, J., Wu, Y., Patel, R., Ramakrishnan, S., Kim, D., Clarke, J., Green, H., Ali, E., DiBona, M., Varice, N., Kundra, R., Broach, V., Gardner, G.J., Long Roche, K., Sonoda, Y., Zivanovic, O., Kim, S.H., Grisham, R.N., Liu, Y.L., Viale, A., Rusk, N., Lakhman, Y., Ellenson, L.H., Tavare, S., Aparicio, S.A.J.R., Chi, D.S., Aghajanian, C., Abu-Rustum, N.R., Friedman, C.F., Bakhoum, S.F., Zamarin, D., Weigelt, B. and Shah, S.P.
bioRxiv
: 2024.07.11.602772v2.
15 July 2024
Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease.
Menacho, C., Okawa, S., Alvarez-Merz, I., Wittich, A., Muñoz-Oreja, M., Lisowski, P., Pentimalli, T.M., Rybak-Wolf, A., Inak, G., Zakin, S., Thevandavakkam, M., Petersilie, L., Zaliani, A., Mlody, B., Seibt, A., Donnelly, J., Woleben, K., Fernandez-Checa, J., Herebian, D., Mayatepek, E., Rajewsky, N., Spinazzola, A., Schuelke, M., Perlstein, E., Rossi, A., Distelmaier, F., Holt, I.J., Pless, O., Rose, C., Del Sol, A. and Prigione, A.
bioRxiv
: 2024.07.08.602501.
12 July 2024
BIQ: A method for searching circular RNAs in transcriptome databases by indexing backsplice junctions.
Menzel, P. and Meyer, I.M.
bioRxiv
: 556993.
25 February 2019
AI-driven Deep Visual Proteomics defines cell identity and heterogeneity.
Mund, A., Coscia, F., Hollandi, R., Kovács, F., Kriston, A., Brunner, A.D., Bzorek, M., Naimy, S., Rahbek Gjerdrum, L.M., Dyring-Andersen, B., Bulkescher, J., Lukas, C., Gnann, C., Lundberg, E., Horvath, P. and Mann, M.
bioRxiv
: 2021.01.25.427969.
27 January 2021
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells.
Muus, C., Luecken, M.D., Eraslan, G., Waghray, A., Heimberg, G., Sikkema, L., Kobayashi, Y., Vaishnav, E.D., Subramanian, A., Smilie, C., Jagadeesh, K., Thu Duong, E., Fiskin, E., Torlai Triglia, E., Ansari, M., Cai, P., Lin, B., Buchanan, J., Chen, S., Shu, J., Haber, A.L., Chung, H., Montoro, D.T., Adams, T., Aliee, H., Allon, S.J., Andrusivova, A.Z., Angelidis, I., Ashenberg, O., Bassler, K., Bécavin, C., Benhar, I., Bergenstråhle, J., Bergenstråhle, L., Bolt, L., Braun, E., Bui, L.T., Chaffin, M., Chichelnitskiy, E., Chiou, J., Conlon, T.M., Cuoco, M.S., Deprez, M., Fischer, D.S., Gillich, A., Gould, J., Guo, M., Gutierrez, A.J., Habermann, A.C., Harvey, T., He, P., Hou, X., Hu, L., Jaiswal, A., Jiang, P., Kapellos, T., Kuo, C.S., Larsson, L., Leney-Greene, M.A., Lim, K., Litviňuková, M., Lu, J., Ludwig, L.S., Luo, W., Maatz, H., Madissoon, E., Mamanova, L., Manakongtreecheep, K., Marquette, C.H., Mbano, I., McAdams, A.M., Metzger, R.J., Nabhan, A.N., Nyquist, S.K., Penland, L., Poirion, O.B., Poli, S., Qi, C.C., Queen, R., Reichart, D., Rosas, I., Schupp, J., Sinha, R., Sit, R.V., Slowikowski, K., Slyper, M., Smith, N., Sountoulidis, A., Strunz, M., Sun, D., Talavera-López, C., Tan, P., Tantivit, J., Travaglini, K.J., Tucker, N.R., Vernon, K., Wadsworth, M.H., Waldman, J., Wang, X., Yan, W., Zhao, W. and Ziegler, C.G.K.
bioRxiv
: 2020.04.19.049254.
21 April 2020
Longitudinal omics in Syrian hamsters integrated with human data unravel cellular effector responses to moderate COVID-19.
Nouailles, Geraldine, Wyler, E., Pennitz, P., Postmus, D., Vladrimirova, D., Kazmierski, J., Pott, F., Dietert, K., Mülleder, M.l, Farztdinov, V., Obermayer, B., Wienhold, S.M., Andreotti, S., Hoefler, T., Sawitzki, B., Drosten, C., Sander, L., Suttorp, N., Ralser, M., Beule, D., Gruber, A., Goffinet, C., Landthaler, M., Trimpert, J. and Witzenrath, M.
Research Square
: rs-148392/v1.
28 January 2021
Chloroplast cold-resistance is mediated by the acidic domain of the RNA binding protein CP31A.
Okuzaki, A., Lehniger, M.K., Muino, J.M., Lenzen, B., Rühe, Thilo, Leister, D., Ohler, U. and Schmitz-Linneweber, C.
bioRxiv
: 832337.
5 December 2019
Pial collaterals develop through mosaic colonization of capillaries by arterial and microvascular endothelial cells.
Perovic, T., Hollfinger, I., Mayer, S., Lips, J., Dopatka, M., Harms, C. and Gerhardt, H.
bioRxiv
: 2023.10.09.561542v3.
7 February 2024
Rewired type I IFN signaling is linked to age-dependent differences in COVID-19.
Petrov, L., Brumhard, S., Wisniewski, S., Georg, P., Hillus, D., Hiller, A., Astaburuaga-García, R., Blüthgen, N., Wyler, E., Vogt, K., Dey, H.P., von Stillfried, S., Iwert, C., Bülow, R.D., Märkl, B., Maas, L., Langner, C., Meyer, T., Loske, J., Eils, R., Lehmann, I., Ondruschka, B., Ralser, M., Trimpert, J., Boor, P., Bedoui, S., Meisel, C., Mall, M.A., Corman, V.M., Sander, L.E., Röhmel, J. and Sawitzki, B.
bioRxiv
: 2024.10.23.619479.
23 October 2024
A fully phased accurate assembly of an individual human genome.
Porubsky, D., Ebert, P., Audano, P.A., Vollger, M.R., Harvey, W.T., Munson, K.M., Sorensen, M., Sulovari, A., Haukness, M., Ghareghani, M., Lansdorp, P.M., Paten, B., Devine, S.E., Sanders, A.D., Lee, C., Chaisson, M.J.P., Korbel, J.O., Eichler, E.E. and Marschall, T.
bioRxiv
: 855049.
26 November 2019
Single-cell transcriptomic analysis of antiviral responses and viral antagonism in Chikungunya virus-infected synovial fibroblasts.
Pott, F., Postmus, D., Brown, R.J.P., Wyler, E., Neumann, E., Landthaler, M. and Goffinet, C.
bioRxiv
: 2020.06.07.138610.
11 June 2021
YAP and β-catenin co-operate to drive oncogenesis in basal breast cancer.
Quinn, H., Koren, E., Vogel, R., Popp, O., Mertins, P., Messerschmidt, C., Marangoni, E., Fuchs, Y. and Birchmeier, W.
bioRxiv
: 2020.06.05.115881.
6 June 2020
The IBEX Knowledge-Base: Achieving more together with open science.
Radtke, A.J., Anidi, I., Arakkal, L., Arroyo-Mejias, A., Beuschel, R.T., Börner, K., Chu, C.J., Clark, B., Clatworthy, M.R., Colautti, J., Croteau, J., Denha, S., Dever, R., Dutra, W.O., Fritzsche, S., Fullam, S., Gerner, M.Y., Gola, A., Gollob, K.J., Hernandez, J.M., Hor, J.L., Ichise, H., Jing, Z., Jonigk, D., Kandov, E., Kastenmüller, W., Koenig, J.F.E., Kothurkar, A., Kreins, A.Y., Lamborn, I., Lin, Y., Luciano Pereira Morais, K., Lunich, A., Luz, J.C.S., MacDonald, R.B., Makranz, C., Maltez, V.I., Moriaty, R.V., Ocampo-Godinez, J.M., Olyntho, V.M., Padhan, K., Remmert, K., Richoz, N., Schrom, E.C., Shang, W., Shi, L., Shih, R.M., Speranza, E., Stierli, S., Teichmann, S.A., Veres, T.Z., Vierhout, M., Wachter, B.T., Wade-Vallance, A.K., Williams, M., Zangger, N., Germain, R.N. and Yaniv, Z.
arXiv
: 2407.19059v1.
26 July 2024
RIF1 acts as a gatekeeper of B cell identity during late differentiation.
Rahjouei, A., Kabrani, E., Berruezo-Llacuna, M., Altwasser, R., Delgado-Benito, V., Pavri, R. and Di Virgilio, M.
bioRxiv
: 2023.07.18.549543v2.
20 July 2023
Investigating the concept of accessibility for predicting novel RNA-RNA interactions.
Reißer, S. and Meyer, I.M.
bioRxiv
: 2021.06.03.446902.
3 June 2021
Quantifying multi-layered expression regulation in response to stress of the endoplasmic reticulum.
Rendleman, J., Cheng, Z., Maity, S., Kastelic, N., Munschauer, M., Allgoewer, K., Teo, G., Zhang, Y.B., Lei, A., Parker, B., Landthaler, M., Freeberg, L., Kuersten, S., Choi, H. and Vogel, C.
bioRxiv
: 308379.
25 April 2018
Non-canonical HIF-1 stabilization is essential for intestinal tumorigenesis.
Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K.T., Fragoulis, A., Kuehl, A.A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C.E., Brenner, W., Malinowski, M.B., Stockmann, M., Schomburg, L., Faller, W., Sansom, O.J., Tacke, F., Morkel, M. and Cramer, T.
bioRxiv
: 273045.
28 February 2018
Sociality shapes mitochondrial adaptations supporting hypoxia tolerance.
Rossi, A., Ruwolt, M., Kakouri, P., Kosten, T., Kunz, S., Puchkov, D., Reznick, J., Purfürst, B., Omerbašić, D., Méndez Aranda, D., Carai, G., Mastrobuoni, G., Hart, D.W., Carraro, M., Tommasin, L., Bennett, N.C., Bégay, V., Faelber, K., Daumke, O., Bernardi, P., Park, T.J., Kempa, S., Liu, F. and Lewin, G.R.
bioRxiv
: 2024.09.30.615914.
2 October 2024
Neurodegeneration in human brain organoids infected with herpes simplex virus type 1.
Rybak-Wolf, A., Wyler, E., Legnini, I., Loewa, A., Glažar, P., Kim, S.J., Pentimalli, T.M., Oliveras Martinez, A., Beyersdorf, B., Woehler, A., Landthaler, M. and Rajewsky, N.
bioRxiv
: 2021.03.05.434122.
7 March 2021
Single cell tri-channel-processing reveals structural variation landscapes and complex rearrangement processes.
Sanders, A.D., Meiers, S., Ghareghani, M., Porubsky, D., Jeong, H., van Vliet, M.A.C.C., Rausch, T., Richter-Pechańska, P., Kunz, J.B., Jenni, S., Raeder, B., Kinanen, V., Zimmermann, J., Benes, V., Schrappe, M., Mardin, B.R., Kulozik, A., Bornhauser, B., Bourquin, J.P., Marschall, T. and Korbel, J.O.
bioRxiv
: 849604.
21 November 2019
Cell-type specific prediction of RNA stability from RNA-protein interactions.
Saran, S., Lebedeva, S., Hirsekorn, A. and Ohler, U.
bioRxiv
: 2024.11.19.624283.
19 November 2024
Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene program in bat wing development.
Schindler, M., Feregrino, C., Aldrovandi, S., Lo, B.W., Monaco, A.A., Ringel, A.R., Morales, A., Zehnder, T., Behncke, R.Y., Glaser, J., Barclay, A., Andrey, G., Kragesteen, B.K., Hägerling, R., Haas, S., Vingron, M., Ulitsky, I., Marti-Renom, M., Hechavarria, J., Fasel, N., Hiller, M., Lupianez, D.G., Mundlos, S. and Real, F.M.
bioRxiv
: 2024.10.10.617585.
13 October 2024
Oncogene inactivation-induced senescence facilitates tumor relapse.
Schmitt, P., Hönig, K., Milojkovic, A., Anders, K., Schröck, E., Sauer, S., Uyar, B., Akalin, A., Martínez-Reyes, I. and Blankenstein, T.
bioRxiv
: 2024.07.13.603369.
17 July 2024
Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex.
Sokpor, Godwin, Ulmke, P.A., Nguyen, H.D., Pham, L., Kakani, P., Chu, V.T., Arnold, S.J., Brand-Saberi, B., Nguyen, H.P. and Tuoc, T.
bioRxiv
: 2024.11.05.621758.
5 November 2024
Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q.
Sollier, E., Riedel, A., Toprak, U.H., Wierzbinska, J.A., Weichenhan, D., Schmid, J.P., Hakobyan, M., Touzart, A., Jahn, E., Vick, B., Brown-Burke, F., Kelly, K., Kelekci, S., Pejkovska, A., Goyal, A., Baehr, M., Breuer, K., Chen, M.J.M., Llamazares-Prada, M., Hartmann, M., Schoenung, M., Correia, N., Trumpp, A., Abdullah, Y., Klingmueller, U., Mughal, S.S., Brors, B., Westermann, F., Schlesner, M., Vosberg, S., Herold, T., Greif, P.A., Pfeifer, D., Luebbert, M., Fischer, T., Heidel, F., Gebhard, C., Walter, W., Haferlach, T., Eisfeld, A.K., Mrozek, K., Nicolet, D., Bullinger, L., Smeenk, L., Erpelinck, C., Mulet-Lazaro, R., Delwel, R., Ernst, A., Scherer, M., Lutsik, P., Jeremias, I., Doehner, K., Doehner, H., Lipka, D.B. and Plass, C.
bioRxiv
: 2024.09.11.611224.
13 September 2024
DNA virus infections shape transposable elements activity in vitro and in vivo.
Tan, J., Franke, V., Neugebauer, E., Lagisquet, J., Kuderna, A.K., Walter, S., Landthaler, M., Ensser, A., Stamminger, T., Gramberg, T., Akalin, A., Wyler, E. and Full, F.
bioRxiv
: 2024.04.18.589901.
19 April 2024
Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury.
Van Steenwinckel, J., Schang, A.L., Krishnan, M.L., Degos, V., Delahaye-Duriez, A., Bokobza, C., Verdonk, F., Montane, A., Sigaut, S., Hennebert, O., Lebon, S., Schwendimann, L., Le Charpentier, T., Hassan-Abdi, R., Ball, G., Aljabar, P., Saxena, A., Holloway, R.K., Birchmeier, W., Miron, V., Rowitch, D., Chretien, F., Leconte, C., Besson, V.C., Petretto, E.G., Edwards, A.D., Hagberg, H., Soussi-Yanicostas, N., Fleiss, B. and Gressens, P.
bioRxiv
: 334359.
31 May 2018
Insulin mRNA is stored in RNA granules in resting beta cells.
Vasiljević, J., Vasiljević, D., Ganß, K., Sönmez, A., Wegbrod, C., Quezada, E., Münster, C., Schöniger, E., Friedland, D., Kipke, N., Distler, M., Selbach, M. and Solimena, M.
bioRxiv
: 2021.05.07.443159.
29 June 2021
Poxviruses induce a nuclear environment in the cytoplasm to promote viral replication.
Veratti, P., Wyler, E., Read, C., Scherer, M., Tan, J., Walther, P., Wider, S., Weidl, D. and Full, F.
bioRxiv
: 2024.11.21.624458.
22 November 2024
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation.
Vučićević, D., Hsu, C.W., Lopez Zepeda, L.S., Burkert, M., Hirsekorn, A., Bilić, I., Kastelić, N., Landthaler, M., Lacadie, S.A. and Ohler, U.
bioRxiv
: 2024.09.12.612198.
12 September 2024
Herpesviral induction of germline transcription factor DUX4 is critical for viral gene expression.
Walter, S., Franke, V., Drayman, N., Wyler, E., Tay, S., Landthaler, M., Akalin, A., Ensser, A. and Full, F.
bioRxiv
: 2021.03.24.436599.
24 March 2021
Cross-platform clinical proteomics using the Charité Open Standard for Plasma Proteomics (OSPP).
Wang, Z., Farztdinov, V., Sinn, L.R., Tober-Lau, P., Ludwig, D., Freiwald, A., Amari, F., Textoris-Taube, K., Niewienda, A., Welter, A.S., Wei, A.A.J., Luckau, L., Kurth, F., Selbach, M., Hartl, J., Mülleder, M. and Ralser, M.
medRxiv
: 2024.05.10.24307167.
10 May 2024
The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells.
Weaver, M.R., Shkoruta, D., Pellegatta, M.R., Berti, C., Palmisano, M., Ferguson, S., Hurley, E., French, J., Patel, S., Belin, S., Selbach, M., Paul, F.E., Sim, F., Poitelon, Y. and Feltri, M.L.
bioRxiv
: 2024.10.30.620661v1.
31 October 2024
Splicing factor Rbm10 facilitates heterochromatin assembly in fission yeast.
Weigt, M., Gao, Q., Ban, H., He, H., Mastrobuoni, G., Kempa, S., Chen, W. and Li, F.
bioRxiv
: 518936.
11 January 2019
Cumulative regulatory potential of clustered methyl-arginine protein modifications.
Woodsmith, J., Casado-Medrano, V., Benlasfer, N., Eccles, R.L., Hutten, S., Heine, C., Thormann, V., Abou-Ajram, C., Rocks, O., Dormann, D. and Stelzl, U.
bioRxiv
: 289041.
26 March 2018
Spatial omics of acute myocardial infarction reveals a novel mode of immune cell infiltration.
Wünnemann, F., Sicklinger, F., Bestak, K., Nimo, J., Thiemann, T., Amrute, J., Nordbeck, M., Hartmann, N., Ibarra-Arellano, M.A., Tanevski, J., Heine, C., Frey, N., Lavine, K.J., Coscia, F., Saez-Rodriguez, J., Leuschner, F. and Schapiro, D.
bioRxiv
: 2024.05.20.594955.
21 May 2024
Insights into therapeutic discovery through the Kelch domain structure of Keap1 at ambient temperature.
Yilmaz, M., Sever, B., Kutlu, Y., Gul, M., Okuducu, C., Tavli, S., Otsuka, M., Fujita, M., Haliloglu, T., Ciftci, H. and DeMirci, H.
bioRxiv
: 2024.07.30.605796.
2 August 2024
Everolimus and mycophenolate mofetil effectively prevent GvHD in children with severe acute kidney injury undergoing allogeneic HSCT.
Zirngibl, F., Gebert, P., Materne, B., Launspach, M., Künkele, A., Hundsdoerfer, P., Cyrull, S., Deubzer, H.E., Kühl, J.S., Eggert, A., Lang, P., Oevermann, L., von Stackelberg, A. and Schulte, J.H.
medRxiv
: 2024.03.14.24304155.
16 March 2024
Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells.
van Bentum, M., Klinger, B., Sieber, A., Lehmann, N., Haji, M., Naghiloo, S., Niquet, S., Mertins, P., Blüthgen, N. and Selbach, M.
bioRxiv
: 2024.05.13.593849.
15 May 2024
Neuromuscular dysfunction in patient-derived FUS(R244RR)-ALS iPSC model via axonal downregulation of neuromuscular junction proteins.
von Kuegelgen, N., Ludwik, K., Mendonsa, S., Roemer, C., Becher, E., Breimann, L., Strauch, M., Mari, T., Mongellaz, S., Zuckerman, B., Grexa, N., Oliveras-Martinez, A., Woehler, A., Selbach, M., La Bella, V., Ulitsky, I. and Chekulaeva, M.
bioRxiv
: 2024.08.17.607965.
17 August 2024
Video
How are different transcripts in our genome translated into proteins?
Ohler, U.
[Video]
2017
Automated two-dimensional spatiotemporal analysis of mobile single-molecule FRET probes.
Schrangl, L., Göhring, J., Kellner, F., Huppa, J.B. and Schütz, G.J.
[Video]
23 November 2021
Other
George Klein: 1925-2016.
Rajewsky, K.
National Academy of Sciences.
28 March 2017
Stefan Jentsch (1955-2016) Obituary.
Sommer, T., Hoppe, T. and Rape, M.
Cell Press.
15 December 2016
Stefan Jentsch (1955-2016) Obituary.
Sommer, T., Hoppe, T. and Rape, M.
Cell Press.
15 December 2016
This list was generated on Thu Dec 26 11:07:37 2024 UTC.