Article
Pan-cancer analysis of whole genomes.
Nature 578
(7793): 82-93.
6 February 2020
Computational pan-genomics: status, promises and challenges.
Briefings in Bioinformatics 19
(1): 118-135.
January 2018
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing.
Abay, T., Stickels, R.R., Takizawa, M.T., Nalbant, B.N., Hsieh, Y.H., Hwang, S., Snopkowski, C., Yu, K.K.H., Abou-Mrad, Z., Tabar, V., Howitt, B.E, Ludwig, L.S., Chaligné, R., Satpathy, A.T and Lareau, C.A.
Nature Genetics
8 January 2025
(In Press)
Phylogenetic ctDNA analysis depicts early stage lung cancer evolution.
Abbosh, C., Birkbak, N.J., Wilson, G.A., Jamal-Hanjani, M., Constantin, T., Salari, R., Quesne, J.L., Moore, D.A., Veeriah, S., Rosenthal, R., Marafioti, T., Kirkizlar, E., Watkins, T.B.K., McGranahan, N., Ward, S., Martinson, L., Riley, J., Fraioli, F., Bakir, M.A., Grönroos, E., Zambrana, F., Endozo, R., Bi, W.L., Fennessy, F.M., Sponer, N., Johnson, D., Laycock, J., Shafi, S., Czyzewska-Khan, J., Rowan, A., Chambers, T., Matthews, N., Turajlic, S., Hiley, C., Lee, S.M., Forster, M.D., Ahmad, T., Falzon, M., Borg, E., Lawrence, D., Hayward, M., Kolvekar, S., Panagiotopoulos, N., Janes, S.M., Thakrar, R., Ahmed, A., Blackhall, F., Summers, Y., Hafez, D., Naik, A., Ganguly, A., Kareht, S., Shah, R., Joseph, L., Quinn, A.M., Crosbie, P., Naidu, B., Middleton, G., Langman, G., Trotter, S., Nicolson, M., Remmen, H., Kerr, K., Chetty, M., Gomersall, L., Fennell, D.A., Nakas, A., Rathinam, S., Anand, G., Khan, S., Russell, P., Ezhil, V., Ismail, B., Irvin-Sellers, M., Prakash, V., Lester, J.F., Kornaszewska, M., Attanoos, R., Adams, H., Davies, H., Oukrif, D., Akarca, A.U., Hartley, J.A., Lowe, H.L., Lock, S., Iles, N., Bell, H., Ngai, Y., Elgar, G., Szallasi, Z., Schwarz, R.F., Herrero, J., Stewart, A., Quezada, S.A., Van Loo, P., Dive, C., Lin, C.J., Rabinowitz, M., Aerts, H.J.W.L., Hackshaw, A., Shaw, J.A., Zimmermann, B.G. and Swanton, C.
Nature 545
(7655): 446-451.
25 May 2017
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Abbosh, C., Frankell, A.M., Harrison, T., Kisistok, J., Garnett, A., Johnson, L., Veeriah, S., Moreau, M., Chesh, A., Chaunzwa, T.L., Weiss, J., Schroeder, M.R., Ward, S., Grigoriadis, K., Shahpurwalla, A., Litchfield, K., Puttick, C., Biswas, D., Karasaki, T., Black, J.R.M., Martínez-Ruiz, C., Bakir, M.A.l., Pich, O., Watkins, T.B.K., Lim, E.L., Huebner, A., Moore, D.A., Godin-Heymann, N., L'Hernault, A., Bye, H., Odell, A., Roberts, P., Gomes, F., Patel, A.J., Manzano, E., Hiley, C.T., Carey, N., Riley, J., Cook, D.E., Hodgson, D., Stetson, D., Barrett, J.C., Kortlever, R.M., Evan, G.I., Hackshaw, A., Daber, R.D., Shaw, J.A., Aerts, H.J.W.L., Licon, A., Stahl, J., Jamal-Hanjani, M., Birkbak, N.J., McGranahan, N. and Swanton, C.
Nature 616
(7957): 553-562.
20 April 2023
Impaired human hematopoiesis due to a cryptic intronic splicing mutation.
Abdulhay, N.J., Fiorini, C., Verboon, J.M., Ludwig, L.S., Ulirsch, J.C., Zieger, B., Lareau, C.A., Mi, X., Roy, A., Obeng, E.A., Erlacher, M., Gupta, N., Gabriel, S.B., Ebert, B.L., Niemeyer, C.M., Khoriaty, R.N., Ancliff, P., Gazda, H.T., Wlodarski, M.W. and Sankaran, V.G.
Journal of Experimental Medicine 216
(5): 1050-1060.
6 May 2019
Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice.
Abolhassani, M., Guais, A., Sanders, E., Campion, F., Fichtner, I., Bonte, J., Baronzio, G., Fiorentini, G., Israel, M. and Schwartz, L.
Investigational New Drugs 30
(4): 1331-1342.
August 2012
Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes.
Abruzzi, K.C., Lacadie, S. and Rosbash, M.
EMBO Journal 23
(13): 2620-2631.
7 July 2004
Comparative evaluation of the biological properties of reducible and acid-sensitive folate prodrugs of a highly potent doxorubicin derivative.
Abu Ajaj, K., El-Abadla, N., Welker, P., Azab, S., Zeisig, R., Fichtner, I. and Kratz, F.
European Journal of Cancer 48
(13): 2054-2065.
September 2012
In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B.
Abu Ajaj, K., Graeser, R., Fichtner, I. and Kratz, F.
Cancer Chemotherapy and Pharmacology 64
(2): 413-418.
July 2009
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous, E.T., Stolzenberg, S., Sticht, J., Wieczorek, M., Roske, Y., Günther, M., Dähn, S., Boesen, B.B., Calvo, M.M., Biese, C., Kuppler, F., Medina-García, Á., Álvaro-Benito, M., Höfer, T., Noé, F. and Freund, C.
Nature Chemical Biology 19
(10): 1196-1204.
October 2023
Malaria-specific antibody responses and parasite persistence after infection of mice with Plasmodium chabaudi chabaudi.
Achtman, A.H., Stephens, R., Cadman, E.T., Harrison, V. and Langhorne, J.
Parasite Immunology 29
(9): 435-444.
September 2007
CCR7-deficient mice develop atypically persistent germinal centers in response to thymus-independent type 2 antigens.
Achtman, A.H., Höpken, U.E., Bernert, C. and Lipp, M.
Journal of Leukocyte Biology 85
(3): 409-417.
March 2009
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.
Ackermann, T., Hartleben, G., Müller, C., Mastrobuoni, G., Groth, M., Sterken, B.A., Zaini, M.A., Youssef, S.A., Zuidhof, H.R., Krauss, S.R., Kortman, G., de Haan, G., de Bruin, A., Wang, Z.Q., Platzer, M., Kempa, S. and Calkhoven, C.F.
Communications Biology 2
: 208.
14 June 2019
Genetic determinants of micronucleus formation in vivo.
Adams, D.J., Barlas, B., McIntyre, R.E., Salguero, I., van der Weyden, L., Barros, A., Vicente, J.R., Karimpour, N., Haider, A., Ranzani, M., Turner, G., Thompson, N.A., Harle, V., Olvera-León, R., Robles-Espinoza, C.D., Speak, A.O., Geisler, N., Weninger, W.J., Geyer, S.H., Hewinson, J., Karp, N.A., Fu, B., Yang, F., Kozik, Z., Choudhary, J., Yu, L., van Ruiten, M.S., Rowland, B.D., Lelliott, C.J., Del Castillo Velasco-Herrera, M., Verstraten, R., Bruckner, L., Henssen, A.G., Rooimans, M.A., de Lange, J., Mohun, T.J., Arends, M.J., Kentistou, K.A., Coelho, P.A., Zhao, Y., Zecchini, H., Perry, J.R.B., Jackson, S.P. and Balmus, G.
Nature 627
(8002): 130-136.
7 March 2024
Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel.
Adema, A.D., Laan, A.C., Myhren, F., Fichtner, I., Verheul, H.M., Sandvold, M.L. and Peters, G.J.
International Journal of Oncology 36
(1): 285-294.
1 January 2010
[S3-Guidelines "Exocrine pancreatic cancer" 2007.] S3-Leitlinie "Exokrines Pankreaskarzinom" 2007.
Adler, G., Seufferlein, T., Bischoff, S.C., Brambs, H.J., Feuerbach, S., Grabenbauer, G., Hahn, S., Heinemann, V., Hohenberger, W., Langrehr, J.M., Lutz, M.P., Neuhaus, H., Neuhaus, P., Oettle, H., Schlag, P.M., Schmid, R., Schmiegel, W., Schlottmann, K., Werner, J., Wiedenmann, B. and Kopp, I.
Zeitschrift fuer Gastroenterologie 45
: 487-523.
June 2007
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8(+) T cell responses.
Agerer, B., Koblischke, M., Gudipati, V., Montaño-Gutierrez, L.F., Smyth, M., Popa, A., Genger, J.W., Endler, L., Florian, D.M., Mühlgrabner, V., Graninger, M., Aberle, S.W., Husa, A.M., Shaw, L.E., Lercher, A., Gattinger, P., Torralba-Gombau, R., Trapin, D., Penz, T., Barreca, D., Fae, I., Wenda, S., Traugott, M., Walder, G., Pickl, W.F., Thiel, V., Allerberger, F., Stockinger, H., Puchhammer-Stöckl, E., Weninger, W., Fischer, G., Hoepler, W., Pawelka, E., Zoufaly, A., Valenta, R., Bock, C., Paster, W., Geyeregger, R., Farlik, M., Halbritter, F., Huppa, J.B., Aberle, J.H. and Bergthaler, A.
Science Immunology 6
(57): eabg6461.
March 2021
T cell homing to tumors detected by 3D-coordinated positron emission tomography and magnetic resonance imaging.
Agger, R., Petersen, M.S., Petersen, C.C., Hansen, S.B., Stodkilde-Jorgensen, H., Skands, U., Blankenstein, T., Andersen, T.E., Hulgaard, E.F., Jorgensen, J.T., Marqversen, J., Gundersen, H.J. and Hokland, M.E.
Journal of Immunotherapy 30
(1): 29-39.
January 2007
A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4(+) T cells and is defective in Crohn's disease patients.
Ahlers, J., Mantei, A., Lozza, L., Stäber, M., Heinrich, F., Bacher, P., Hohnstein, T., Menzel, L., Yüz, S.G., Alvarez-Simon, D., Bickenbach, A.R., Weidinger, C., Mockel-Tenbrinck, N., Kühl, A.A., Siegmund, B., Maul, J., Neumann, C. and Scheffold, A.
Mucosal Immunology 15
(3): 480-490.
May 2022
Nicotine strongly activates dendritic cell-mediated adaptive immunity - Potential role for progression of atherosclerotic lesions.
Aicher, A., Heeschen, C., Mohaupt, M., Cooke, J.P., Zeiher, A.M. and Dimmeler, S.
Circulation 107
(4): 604-611.
4 February 2003
1H, 15N and 13C assignments of the cysteine protease inhibitor Chagasin from Trypanosoma cruzi.
Aido-Machado, R., Salmon, D., Diehl, A., Leidert, M., Schmetzer, O., de Lima, A.P.C.A., Scharfstein, J., Oschkinat, H. and Pires, J.R.
Journal of Biomolecular NMR 36 (Suppl)
(1): 30.
December 2006
Gab1 and Mapk signaling are essential in the hair cycle and hair follicle stem cell quiescence.
Akilli Öztürk, Ö., Pakula, H., Chmielowiec, J., Qi, J., Stein, S., Lan, L., Sasaki, Y., Rajewsky, K. and Birchmeier, W.
Cell Reports 13
(3): 561-572.
20 October 2015
The evolution of non-small cell lung cancer metastases in TRACERx.
Al Bakir, M., Huebner, A., Martínez-Ruiz, C., Grigoriadis, K., Watkins, T.B.K., Pich, O., Moore, D.A., Veeriah, S., Ward, S., Laycock, J., Johnson, D., Rowan, A., Razaq, M., Akther, M., Naceur-Lombardelli, C., Prymas, P., Toncheva, A., Hessey, S., Dietzen, M., Colliver, E., Frankell, A.M., Bunkum, A., Lim, E.L., Karasaki, T., Abbosh, C., Hiley, C.T., Hill, M.S., Cook, D.E., Wilson, G.A., Salgado, R., Nye, E., Stone, R.K., Fennell, D.A., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Summers, Y., Lindsay, C.R., Blackhall, F.H., Cave, J., Blyth, K.G., Nair, A., Ahmed, A., Taylor, M.N., Procter, A.J., Falzon, M., Lawrence, D., Navani, N., Thakrar, R.M., Janes, S.M., Papadatos-Pastos, D., Forster, M.D., Lee, S.M., Ahmad, T., Quezada, S.A., Peggs, K.S., Van Loo, P., Dive, C., Hackshaw, A., Birkbak, N.J., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
(7957): 534-542.
April 2023
Body composition and lung cancer-associated cachexia in TRACERx.
Al-Sawaf, O., Weiss, J., Skrzypski, M., Lam, J.M., Karasaki, T., Zambrana, F., Kidd, A.C., Frankell, A.M., Watkins, T.B.K., Martínez-Ruiz, C., Puttick, C., Black, J.R.M., Huebner, A., Bakir, M.A., Sokač, M., Collins, S., Veeriah, S., Magno, N., Naceur-Lombardelli, C., Prymas, P., Toncheva, A., Ward, S., Jayanth, N., Salgado, R., Bridge, C.P., Christiani, D.C., Mak, R.H., Bay, C., Rosenthal, M., Sattar, N., Welsh, P., Liu, Y., Perrimon, N., Popuri, K., Beg, M.F., McGranahan, N., Hackshaw, A., Breen, D.M., O'Rahilly, S., Birkbak, N.J., Aerts, H.J.W.L., Jamal-Hanjani, M. and Swanton, C.
Nature Medicine 29
(4): 846-858.
April 2023
Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A., Xavier, A., Abu Lubad, M., Sigulla, J., Kessler, M., Hurwitz, R. and Meyer, T.F.
EBioMedicine 23
: 100-110.
September 2017
The metabolic background is a global player in Saccharomyces gene expression epistasis.
Alam, M.T., Zelezniak, A., Mülleder, M., Shliaha, P., Schwarz, R., Capuano, F., Vowinckel, J., Radmaneshfar, E., Krüger, A., Calvani, E., Michel, S., Börno, S., Christen, S., Patil, K.R., Timmermann, B., Lilley, K.S. and Ralser, M.
Nature Microbiology 1
: 15030.
1 February 2016
From operating table to laboratory bench: the path toward metastasis research from the clinical setting.
Alberto Vilchez, M. and Rau, B.
Methods in Molecular Biology 2294
: 325-333.
2021
Distinct functional properties of the TAP subunits coordinate the nucleotide-dependent transport cycle.
Alberts, P., Daumke, O., Deverson, E.V., Howard, J.C. and Knittler, M.R.
Current Biology 11
(4): 242-51.
20 February 2001
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H., Flórez, A.F., Kreth, S., Brückner, L.M., Yildiz, U., Gartlgruber, M., Odoni, D.I., Poschet, G., Garbowicz, K., Shao, C., Klein, C., Meier, J., Zeisberger, P., Nadler-Holly, M., Ziehm, M., Paul, F., Burhenne, J., Bell, E., Shaikhkarami, M., Würth, R., Stainczyk, S.A., Wecht, E.M., Kreth, J., Büttner, M., Ishaque, N., Schlesner, M., Nicke, B., Stresemann, C., Llamazares-Prada, M., Reiling, J.H., Fischer, M., Amit, I., Selbach, M., Herrmann, C., Wölfl, S., Henrich, K.O., Höfer, T., Trumpp, A. and Westermann, F.
Nature Cancer 3
(4): 471-485.
28 April 2022
Spontaneous non-sustained ventricular tachycardia and premature ventricular contractions and their prognostic relevance in patients with cancer in routine care.
Albrecht, A., Porthun, J., Eucker, J., Coats, A.J.S., von Haehling, S., Pezzutto, A., Karakas, M., Riess, H., Keller, U., Landmesser, U., Haverkamp, W., Anker, S.D. and Anker, M.S.
Cancers 13
(10): 2303.
12 May 2021
Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Alcaniz, J., Winkler, L., Dahlmann, M., Becker, M., Orthmann, A., Haybaeck, J., Krassnig, S., Skofler, C., Kratzsch, T., Kuhn, S.A., Jödicke, A., Linnebacher, M., Fichtner, I., Walther, W. and Hoffmann, J.
Frontiers in Oncology 13
: 1129627.
11 April 2023
Characterization of protein-binding to the spinach chloroplast psbA mRNA 5' untranslated region.
Alexander, C., Faber, N. and Klaff, P.
Nucleic Acids Research 26
(10): 2265-2272.
15 May 1998
Tumor-derived extracellular vesicles impair CD171-specific CD4(+) CAR T cell efficacy.
Ali, S., Toews, K., Schwiebert, S., Klaus, A., Winkler, A., Grunewald, L., Oevermann, L., Deubzer, H.E., Tüns, A., Jensen, M.C., Henssen, A.G., Eggert, A., Schulte, J.H., Schwich, E., Rebmann, V., Schramm, A. and Künkele, A.
Frontiers in Immunology 11
: 531.
31 March 2020
Cell fixation and preservation for droplet-based single-cell transcriptomics.
Alles, J., Karaiskos, N., Praktiknjo, S.D., Grosswendt, S., Wahle, P., Ruffault, P.L., Ayoub, S., Schreyer, L., Boltengagen, A., Birchmeier, C., Zinzen, R., Kocks, C. and Rajewsky, N.
BMC Biology 15
(1): 44.
19 May 2017
Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L., Peeva, P., Ramos-Prats, A., Alenina, N., Winter, Y. and Rivalan, M.
Behavioural Brain Research 377
: 112188.
13 January 2020
Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology.
Amthauer, H., Denecke, T., Rau, B., Hildebrandt, B., Huenerbein, M., Ruf, J., Schneider, U., Gutberlet, M., Schlag, P.M., Felix, R. and Wust, P.
European Journal of Nuclear Medicine and Molecular Imaging 31
(6): 811-819.
1 January 2004
In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C., Acemel, R.D., Jedamzick, J., Bolondi, A., Cova, G., Brieske, N., Kühn, R., Wittler, L., Real, F.M. and Lupiáñez, D.G.
Nature Genetics 54
(7): 1026-1036.
July 2022
Molecular pathways: comparing the effects of drugs and T cells to effectively target oncogenes.
Anders, K. and Blankenstein, T.
Clinical Cancer Research 19
(2): 320-326.
15 January 2013
Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.
Anders, K., Buschow, C., Charo, J. and Blankenstein, T.
Transgenic Research 21
(5): 1099-1107.
October 2012
Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K., Buschow, C., Herrmann, A., Milojkovic, A., Loddenkemper, C., Kammertoens, T., Daniel, P., Yu, H., Charo, J. and Blankenstein, T.
Cancer Cell 20
(6): 755-767.
13 December 2011
Microarray meta-analysis defines global angiogenesis-related gene expression signatures in human carcinomas.
Anders, M., Fehlker, M., Wang, Q., Wissmann, C., Pilarsky, C., Kemmner, W. and Hoecker, M.
Molecular Carcinogenesis 52
(1): 29-38.
January 2013
Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression.
Anders, M., Vieth, M., Roecken, C., Ebert, M., Pross, M., Gretschel, S., Schlag, P.M., Wiedenmann, B., Kemmner, W. and Hoecker, M.
British Journal of Cancer 100
(2): 352-359.
27 January 2009
The immune system prevents recurrence of transplanted but not autochthonous antigenic tumors after oncogene inactivation therapy.
Anders, K., Kershaw, O., Larue, L., Gruber, A.D. and Blankenstein, T.
International Journal of Cancer 141
(12): 2551-2561.
15 December 2017
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing.
Andersch, L., Radke, J., Klaus, A., Schwiebert, S., Winkler, A., Schumann, E., Grunewald, L., Zirngibl, F., Flemmig, C., Jensen, M.C., Rossig, C., Joussen, A., Henssen, A., Eggert, A., Schulte, J.H. and Künkele, A.
BMC Cancer 19
(1): 895.
9 September 2019
Phosphorylation-dependent down-regulation of c-Myb DNA binding is abrogated by a point mutation in the v-myb oncogene.
Andersson, K.B., Kowenz-Leutz, E., Brendeford, E.M., Tygsett, A.H.H., Leutz, A. and Gabrielsen, O.S.
Journal of Biological Chemistry 278
(6): 3816-3824.
7 February 2003
Mining the literature: new methods to exploit keyword profiles.
Andrade-Navarro, M.A.
Genome Medicine 4
(10): 81.
30 October 2012
A method for cell type marker discovery by high-throughput gene expression analysis of mixed cell populations.
Andrade-Navarro, M.A., Kanji, F., Palii, C.G., Brand, M., Atkins, H. and Perez-Iratxeta, C.
BMC Biotechnology 13
(1): 80.
3 October 2013
De novo whole genome assembly of the Roborovski dwarf hamster (Phodopus roborovskii) genome, an animal model for severe/critical COVID-19.
Andreotti, S., Altmüller, J., Quedenau, C., Borodina, T., Nouailles, G., Teixeira Alves, L.G., Landthaler, M., Bieniara, M., Trimpert, J. and Wyler, E.
Genome Biology and Evolution 14
(7): evac100.
July 2022
An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.
Andres, D., Gohlke, U., Broeker, N.K., Schulze, S., Rabsch, W., Heinemann, U., Barbirz, S. and Seckler, R.
Glycobiology 23
(4): 486-494.
April 2013
Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system.
Andresen, D., Roske, Y., Doering, C., Heinemann, U., Seckler, R. and Barbirz, S.
Molecular Microbiology 83
(6): 1244-1253.
March 2012
CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition.
Andreu-Saumell, I., Rodriguez-Garcia, A., Mühlgrabner, V., Gimenez-Alejandre, M., Marzal, B., Castellsagué, J., Brasó-Maristany, F., Calderon, H., Angelats, L., Colell, S., Nuding, M., Soria-Castellano, M., Barbao, P., Prat, A., Urbano-Ispizua, A., Huppa, J.B. and Guedan, S.
Nature Communications 15
(1): 3552.
26 April 2024
destiny: diffusion maps for large-scale single-cell data in R.
Angerer, P., Haghverdi, L., Büttner, M., Theis, F.J., Marr, C. and Buettner, F.
Bioinformatics 32
(8): 1241-1243.
15 April 2016
Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming.
Anh, L.P.H., Nishimura, K., Kuno, A., Nguyen, T.L., Kato, T., Ohtaka, M., Nakanishi, M., Sugihara, E., Sato, T.A., Hayashi, Y., Fukuda, A. and Hisatake, K.
Stem Cells 40
(4): 397-410.
29 April 2022
New cardiovascular biomarkers in patients with advanced cancer – a prospective study comparing MR-proADM, MR-proANP, copeptin, high-sensitivity troponin T and NT-proBNP.
Anker, M.S., Lück, L.C., Khan, M.S., Porthun, J., Hadzibegovic, S., Lena, A., Wilkenshoff, U., Weinländer, P., Evertz, R., Totzeck, M., Mahabadi, A.A., Rassaf, T., Anker, S.D., Bullinger, L., Keller, U., Karakas, M., Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure
26 November 2024
(In Press)
Patient-reported ability to walk 4 m and to wash: New clinical endpoints and predictors of survival in patients with pre-terminal cancer.
Anker, M.S., Lena, A., Roeland, E.J., Porthun, J., Schmitz, S., Hadzibegovic, S., Sikorski, P., Wilkenshoff, U., Fröhlich, A.K., Ramer, L.V., Rose, M., Eucker, J., Rassaf, T., Totzeck, M., Lehmann, L.H., von Haehling, S., Coats, A.J.S., Friede, T., Butler, J., Anker, S.D., Riess, H., Landmesser, U., Bullinger, L., Keller, U. and Ahn, J.
Journal of Cachexia Sarcopenia and Muscle 14
(4): 1670-1681.
August 2023
Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire.
Anker, M.S., Potthoff, S.K., Lena, A., Porthun, J., Hadzibegovic, S., Evertz, R., Denecke, C., Fröhlich, A.K., Sonntag, F., Regitz-Zagrosek, V., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Spertus, J.A., Anker, S.D., Karakas, M., Bullinger, L., Keller, U., Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 25
(9): 1635-1647.
September 2023
B-Myb, a repressed trans-activating protein.
Ansieau, S., Kowenz-Leutz, E., Dechend, R. and Leutz, A.
Journal of Molecular Medicine 75
(11-12): 815-819.
November 1997
Early life stress regulates cardiac development through an IL4-glucocorticoid signaling balance.
Apaydin, D.C., Jaramillo, P.A.M., Corradi, L., Cosco, F., Rathjen, F.G., Kammertoens, T., Filosa, A. and Sawamiphak, S.
Cell Reports 33
(7): 108404.
17 November 2020
Functionalized bead assay to measure three-dimensional traction forces during T-cell activation.
Aramesh, M., Mergenthal, S., Issler, M., Plochberger, B., Weber, F., Qin, X.H., Liska, R., Duda, G.N., Huppa, J.B., Ries, J., Schütz, G.J. and Klotzsch, E.
Nano Letters 21
(1): 507-514.
13 January 2021
CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations.
Arce, S., Luger, E., Muehlinghaus, G., Cassese, G., Hauser, A., Horst, A., Lehnert, K., Odendahl, M., Hoenemann, D., Heller, K.D., Kleinschmidt, H., Berek, C., Doerner, T., Krenn, V., Hiepe, F., Bargou, R., Radbruch, A. and Manz, R.A.
Journal of Leukocyte Biology 75
: 1022-1028.
1 January 2004
Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M., Dimitriou, S., Stahler, A., Hablesreiter, R., Strzelecka, P.M., Stein, C.M., Tilgner, M., Saiki, R., Ogawa, S., Bullinger, L., Modest, D.P., Stintzing, S., Heinemann, V. and Damm, F.
Blood 139
(10): 1593-1597.
10 March 2022
Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.
Arends, C.M., Galan-Sousa, J., Hoyer, K., Chan, W., Jäger, M., Yoshida, K., Seemann, R., Noerenberg, D., Waldhueter, N., Fleischer-Notter, H., Christen, F., Schmitt, C.A., Dörken, B., Pelzer, U., Sinn, M., Zemojtel, T., Ogawa, S., Märdian, S., Schreiber, A., Kunitz, A., Krüger, U., Bullinger, L., Mylonas, E., Frick, M. and Damm, F.
Leukemia 32
(9): 1908-1919.
September 2018
Dynamics of clonal hematopoiesis under DNA-damaging treatment in patients with ovarian cancer.
Arends, C.M., Kopp, K., Hablesreiter, R., Estrada, N., Christen, F., Moll, U.M., Zeillinger, R., Schmitt, W.D., Sehouli, J., Kulbe, H., Fleischmann, M., Ray-Coquard, I., Zeimet, A., Raspagliesi, F., Zamagni, C., Vergote, I., Lorusso, D., Concin, N., Bullinger, L., Braicu, E.I. and Damm, F.
Leukemia 38
(6): 1378-1389.
June 2024
Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M., Liman, T.G., Strzelecka, P.M., Kufner, A., Löwe, P., Huo, S., Stein, C.M., Piper, S.K., Tilgner, M., Sperber, P.S., Dimitriou, S., Heuschmann, P., Hablesreiter, R., Harms, C., Bullinger, L., Weber, J.E., Endres, M. and Damm, F.
Blood 141
(7): 787-799.
16 February 2023
Eukaryotic expression: developments for structural proteomics.
Aricescu, A.R., Assenberg, R., Bill, R.M., Busso, D., Chang, V.T., Davis, S.J., Dubrovsky, A., Gustafsson, L., Hedfalk, K., Heinemann, U., Jones, I.M., Ksiazek, D., Lang, C., Maskos, K., Messerschmidt, A., Macieira, S., Peleg, Y., Perrakis, A., Poterszman, A., Schneider, G., Sixma, T.K., Sussman, J.L., Sutton, G., Tarboureich, N., Zeev-Ben-Mordehai, T. and Jones, E.Y.
Acta Crystallographica Section D 62
(Pt. 10): 1114-1124.
October 2006
Colon cancer metastasis: MACC1 and Met as metastatic pacemakers.
Arlt, F. and Stein, U.
International Journal of Biochemistry and Cell Biology 41
(12): 2356-2359.
December 2009
Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect.
Arlt, B., Mastrobuoni, G., Wuenschel, J., Astrahantseff, K., Eggert, A., Kempa, S. and Deubzer, H.E.
Journal of Enzyme Inhibition and Medicinal Chemistry 36
(1): 1282-1289.
30 June 2021
Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt, B., Zasada, C., Baum, K., Wuenschel, J., Mastrobuoni, G., Lodrini, M., Astrahantseff, K., Winkler, A., Schulte, J.H., Finkler, S., Forbes, M., Hundsdoerfer, P., Guergen, D., Hoffmann, J., Wolf, J., Eggert, A., Kempa, S. and Deubzer, H.E.
International Journal of Cancer 148
(5): 1219-1232.
1 March 2021
SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K., Kranz, A., Fohgrub, J., Jolly, A., Bledau, A.S., Di Virgilio, M., Lesche, M., Dahl, A., Höfer, T., Stewart, A.F. and Waskow, C.
Blood 131
(12): 1311-1324.
22 March 2018
Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.
Arnhold, V., Schmelz, K., Proba, J., Winkler, A., Wünschel, J., Toedling, J., Deubzer, H.E., Künkele, A., Eggert, A., Schulte, J.H. and Hundsdoerfer, P.
Oncotarget 9
(2): 2304-2319.
2018
The germinal center response is impaired in the absence of T cell-expressed CXCR5.
Arnold, C.N., Campbell, D.J., Lipp, M. and Butcher, E.C.
European Journal of Immunology 37
(1): 100-109.
January 2007
Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Horst, D., Rau, B., Stein, U. and Treese, C.
Pathology Research and Practice 215
(11): 152662.
November 2019
Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. and Treese, C.
Clinical and Translational Oncology 22
(12): 2357-2363.
December 2020
Immunohistochemical analysis of nicotinamide phosphoribosyltransferase expression in gastric and esophageal adenocarcinoma (AEG).
Arnold, A., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Krenzien, F., Stein, U. and Treese, C.
Gastrointestinal Disorders 4
(4): 333-340.
13 December 2022
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A., Roske, Y., Barth, C., Lleras Forero, L., Bravo-Rodriguez, K., Redel, Al., Kostova, S., McShane, E., Opitz, R., Faelber, K., Rau, K., Mielke, T., Daumke, O., Selbach, M., Sanchez-Garcia, E., Rocks, O., Panáková, D., Heinemann, U. and Wanker, E.E.
Nature Communications 7
: 13047.
20 October 2016
An alignment-free method to identify candidate orthologous enhancers in multiple Drosophila genomes.
Arunachalam, M., Jayasurya, K., Tomancak, P. and Ohler, U.
Bioinformatics 26
(17): 2109-2115.
1 September 2010
Prospective tracking of donor-reactive T-cell clones in the circulation and rejecting human kidney allografts.
Aschauer, C., Jelencsics, K., Hu, K., Heinzel, A., Gregorich, M.G., Vetter, J., Schaller, S., Winkler, S.M., Weinberger, J., Pimenov, L., Gualdoni, G.A., Eder, M., Kainz, A., Troescher, A.R., Regele, H., Reindl-Schwaighofer, R., Wekerle, T., Huppa, J.B., Sykes, M. and Oberbauer, R.
Frontiers in Immunology 12
: 750005.
14 October 2021
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C., Mouktaroudi, M., Krämer, B., Oestreich, M., Antonakos, N., Nuesch-Germano, M., Gkizeli, K., Bonaguro, L., Reusch, N., Baßler, K., Saridaki, M., Knoll, R., Pecht, T., Kapellos, T.S., Doulou, S., Kröger, C., Herbert, M., Holsten, L., Horne, A., Gemünd, I.D., Rovina, N., Agrawal, S., Dahm, K., van Uelft, M., Drews, A., Lenkeit, L., Bruse, N., Gerretsen, J., Gierlich, J., Becker, M., Händler, K., Kraut, M., Theis, H., Mengiste, S., Domenico, E., Schulte-Schrepping, J., Seep, L., Raabe, J., Hoffmeister, C., ToVinh, M., Keitel, V., Rieke, G., Talevi, V., Skowasch, D., Aziz, N.A., Pickkers, P., van de Veerdonk, F.L., Netea, M.G., Schultze, J.L., Kox, M., Breteler, M.M.B., Nattermann, J., Koutsoukou, A., Giamarellos-Bourboulis, E.J. and Ulas, T.
Genome Medicine 13
(1): 7.
13 January 2021
Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles.
Aschman, T., Wyler, E., Baum, O., Hentschel, A., Rust, R., Legler, F., Preusse, C., Meyer-Arndt, L., Büttnerova, I., Förster, A., Cengiz, D., Teixeira Alves, L.G., Schneider, J., Kedor, C., Bellmann-Strobl, J., Sanchin, A., Goebel, H.H., Landthaler, M., Corman, V., Roos, A., Heppner, F.L., Radbruch, H., Paul, F., Scheibenbogen, C., Dengler, N.F. and Stenzel, W.
Acta Neuropathologica Communications 11
(1): 193.
8 December 2023
Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.
Ash, M.R., Faelber, K., Kosslick, D., Albert, G.I., Roske, Y., Kofler, M., Schuemann, M., Krause, E. and Freund, C.
Structure 18
(8): 944-954.
11 August 2010
Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk.
Ashktorab, H., Hermann, P., Nouraie, M., Shokrani, B., Lee, E., Haidary, T., Brim, H. and Stein, U.
Journal of Translational Medicine 14
(1): 215.
20 July 2016
Saffron: The golden spice with therapeutic properties on digestive diseases.
Ashktorab, H., Soleimani, A., Singh, G., Amr, A., Tabtabaei, S., Latella, G., Stein, U., Akhondzadeh, S., Solanki, N., Gondré-Lewis, M.C., Habtezion, A. and Brim, H.
Nutrients 11
(5): 943.
26 April 2019
Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.
Aslam, M.A., Alemdehy, M.F., Kwesi-Maliepaard, E.M., Muhaimin, F.I., Caganova, M., Pardieck, I.N., van den Brand, T., van Welsem, T., de Rink, I., Song, J.Y., de Wit, E., Arens, R., Jacobs, H. and van Leeuwen, F.
EMBO Reports 22
(2): e51184.
3 February 2021
CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia.
Astori, A., Fredly, H., Aloysius, T.A., Bullinger, L., Mansat-De Mas, V., de la Grange, P., Delhommeau, F., Hagen, K.M., Récher, C., Dusanter-Fourt, I., Knappskog, S., Lillehaug, J.R., Pendino, F. and Bruserud, Ø.
Oncotarget 4
(9): 1438-1448.
September 2013
REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis.
Astrosini, C., Roeefzaad, C., Dai, Y.Y., Dieckgraefe, B.K., Joens, T. and Kemmner, W.
International Journal of Cancer 123
(2): 409-413.
15 July 2008
Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.
Augustin, I., Gross, J., Baumann, D., Korn, C., Kerr, G., Grigoryan, T., Mauch, C., Birchmeier, W. and Boutros, M.
Journal of Experimental Medicine 210
(9): 1761-1777.
26 August 2013
IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors.
Authier, H., Billot, K., Derudder, E., Bordereaux, D., Riviere, P., Rodrigues-Ferreira, S., Nahmias, C. and Baud, V.
Proceedings of the National Academy of Sciences of the United States of America 111
(41): 14794-14799.
14 October 2014
The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches.
Avancena, P., Song, T., Yao, Y., Fehlner-Peach, H., Diamond, B., Gu, H., Rajewsky, K. and Zou, Y.R.
Proceedings of the National Academy of Sciences of the United States of America 118
(30): e2100576118.
27 July 2021
Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface.
Avery, E.G., Haag, L.M., McParland, V., Kedziora, S.M., Zigra, G.J., Valdes, D.S., Kirchner, M., Popp, O., Geisberger, S., Nonn, O., Karlsen, T.V., N'Diaye, G., Yarritu, A., Bartolomaeus, H., Bartolomaeus, T.U.P., Tagiyeva, N.A., Wimmer, M.I., Haase, N., Zhang, Y.D., Wilhelm, A., Grütz, G., Tenstad, O., Wilck, N., Forslund, S.K., Klopfleisch, R., Kühl, A.A., Atreya, R., Kempa, S., Mertins, P., Siegmund, B., Wiig, H. and Müller, D.N.
Cardiovascular Research
: cvae267.
13 January 2025
(In Press)
Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol.
Avvakumov, G.V., Grishkovskaya, I., Muller, Y.A. and Hammond, G.L.
Journal of Biological Chemistry 277
(47): 45219-45225.
22 November 2002
Determination of interaction kinetics between the T cell receptor and peptide-loaded MHC class II via single-molecule diffusion measurements.
Axmann, M., Huppa, J.B., Davis, M.M. and Schütz, G.J.
Biophysical Journal 103
(2): L17-9.
18 July 2012
Single molecule fluorescence microscopy on planar supported bilayers.
Axmann, M., Schütz, G.J. and Huppa, J.B.
Journal of Visualized Experiments
(105): e53158.
31 October 2015
Measuring TCR-pMHC binding in situ using a FRET-based microscopy assay.
Axmann, M., Schütz, G.J. and Huppa, J.B.
Journal of Visualized Experiments
(105): e53157.
30 October 2015
Structure and function of the Bacillus hybrid enzyme GluXyn-1: Native-like jellyroll fold preserved after insertion of autonomous globular domain.
Ay, J., Goetz, F., Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 95
(12): 6613-6618.
9 June 1998
Steady state migratory RelB(+) Langerin(+) dermal dendritic cells mediate peripheral induction of antigen-specific CD4(+) CD25(+) Foxp3(+) regulatory T cells.
Azukizawa, H., Doehler, A., Kanazawa, N., Nayak, A., Lipp, M., Malissen, B., Autenrieth, I., Katayama, I., Riemann, M., Weih, F., Berberich-Siebelt, F. and Lutz, M.B.
European Journal of Immunology 41
(5): 1420-1434.
May 2011
A rapid embryonic stem cell-based mouse model for B-cell lymphomas driven by Epstein-Barr virus protein LMP1.
Ba, Z., Meng, F.L., Gostissa, M., Huang, P.Y., Ke, Q., Wang, Z., Dao, M.N., Fujiwara, Y., Rajewsky, K., Zhang, B. and Alt, F.W.
Cancer Immunology Research 3
(6): 641-649.
June 2015
Loss of m(1)acp(3)Ψ ribosomal RNA modification is a major feature of cancer.
Babaian, A., Rothe, K., Girodat, D., Minia, I., Djondovic, S., Milek, M., Spencer Miko, S.E., Wieden, H.J., Landthaler, M., Morin, G.B. and Mager, D.L.
Cell Reports 31
(5): 107611.
5 May 2020
Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome.
Babaylova, E., Graifer, D., Malygin, A., Stahl, J., Shatsky, I. and Karpova, G.
Nucleic Acids Research 37
(4): 1141-1151.
March 2009
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.
Baccin, C., Al-Sabah, J., Velten, L., Helbling, P.M., Grünschläger, F., Hernández-Malmierca, P., Nombela-Arrieta, C., Steinmetz, L.M., Trumpp, A. and Haas, S.
Nature Cell Biology 22
(1): 38-48.
January 2020
Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells.
Bachmeier, B., Fichtner, I., Killian, P.H., Kronski, E., Pfeffer, U. and Efferth, T.
PLoS ONE 6
(5): e20550.
26 May 2011
STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis.
Backert, I., Koralov, S.B., Wirtz, S., Kitowski, V., Billmeier, U., Martini, E., Hofmann, K., Hildner, K., Wittkopf, N., Brecht, K., Waldner, M., Rajewsky, K., Neurath, M.F., Becker, C. and Neufert, C.
Journal of Immunology 193
(7): 3779-3791.
1 October 2014
RNA-bioinformatics: tools, services and databases for the analysis of RNA-based regulation.
Backofen, R., Engelhardt, J., Erxleben, A., Fallmann, J., Grüning, B., Ohler, U., Rajewsky, N. and Stadler, P.F.
Journal of Biotechnology 261
: 76-84.
10 November 2017
Suppression of peripheral pain by blockade of voltage-gated calcium 2.2 channels in nociceptors induces RANKL and impairs recovery from inflammatory arthritis in a mouse model.
Baddack, U., Frahm, S., Antolin-Fontes, B., Grobe, J., Lipp, M., Mueller, G. and Ibanez-Tallon, I.
Arthritis & Rheumatology 67
(6): 1657-1667.
June 2015
A chronic model of arthritis supported by a strain-specific periarticular lymph node in BALB/c mice.
Baddack, U., Hartmann, S., Bang, H., Grobe, J., Loddenkemper, C., Lipp, M. and Mueller, G.
Nature Communications 4
: 1644.
2013
Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis.
Baddack-Werncke, U., Busch-Dienstfertig, M., Gonzalez-Rodriguez, S., Maddila, S.C., Grobe, J., Lipp, M., Stein, C. and Mueller, G.
Journal of Neuroinflammation 14
(1): 30.
6 February 2017
Apoptosis-induced cleavage of keratin 15 and keratin 17 in a human breast epithelial cell line.
Badock, V., Steinhusen, U., Bommert, K., Wittmann-Liebold, B. and Otto, A.
Cell Death and Differentiation 8
(3): 308-315.
1 March 2001
Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K., von Delbrück, M., Dittmar, G., Scheffner, M., Ziv, I., Glickman, M.H., Ciechanover, A. and Sommer, T.
Molecular Cell 50
(4): 528-539.
23 May 2013
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey, M.H., Meyerson, W.U., Dursi, L.J., Wang, L.B., Dong, G., Liang, W.W., Weerasinghe, A., Li, S., Li, Y., Kelso, S., Saksena, G., Ellrott, K., Wendl, M.C., Wheeler, D.A., Getz, G., Simpson, J.T., Gerstein, M.B. and Ding, Li
Nature Communications 11
(1): 4748.
21 September 2020
Essential role of c-myc in ara-C-induced differentiation of human erythroleukemia cells.
Baker, S.J., Pawlita, M., Leutz, A. and Hoelzer, D.
Leukemia 8
(8): 1309-1317.
August 1994
In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia.
Bakina, O., Conrad, T., Mitic, N., Vidal, R.O., Obrusnik, T., Sai, S., Nolte, C., Semtner, M. and Kettenmann, H.
PLoS ONE 19
(7): e0302376.
11 July 2024
Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S., Andreani, M., Goncalves Andrade, J., Saha, T., Sundaravinayagam, D., Garzón, J., Zhang, W., Popp, O., Hiraga, S., Rahjouei, A., Rosen, D.B., Mertins, P., Chait, B.T., Donaldson, A.D. and Di Virgilio, M.
eLife 11
: e75047.
13 April 2022
Binding of Drosophila ORC proteins to anaphase chromosomes requires cessation of mitotic cyclin-dependent kinase activity.
Baldinger, T. and Gossen, M.
Molecular and Cellular Biology 29
(1): 140-149.
January 2009
Immune phenotypes and checkpoint molecule expression of clonally expanded lymph node-infiltrating T cells in classical Hodgkin lymphoma.
Ballhausen, A., Ben Hamza, A., Welters, C., Dietze, K., Bullinger, L., Rahn, H.P., Hartmann, S., Hansmann, M.L. and Hansmann, L.
Cancer Immunology Immunotherapy 72
(2): 515-521.
February 2023
Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR.
Balyschew, N., Yushkevich, A., Mikirtumov, V., Sanchez, R.M., Sprink, T. and Kudryashev, M.
Nature Communications 14
(1): 6543.
17 October 2023
Role of β-catenin in synaptic vesicle localization and presynaptic assembly.
Bamji, S.X., Shimazu, K., Kimes, N., Huelsken, J., Birchmeier, W., Lu, B. and Reichardt, L.F.
Neuron 40
(4): 719-731.
November 2003
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembling cofactors ASPL/PUX1.
Banchenko, S., Arumughan, A., Petrović, S., Schwefel, D., Wanker, E.E., Roske, Y. and Heinemann, U.
Structure 27
(12): 1830-1841.
3 December 2019
First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.
Banci, L., Bertini, I., Cusack, S., de Jong, R.N., Heinemann, U., Jones, E.Y., Kozielski, F., Maskos, K., Messerschmidt, A., Owens, R., Perrakis, A., Poterszman, A., Schneider, G., Siebold, C., Silman, I., Sixma, T., Stewart-Jones, G., Sussman, J.L., Thierry, J.C. and Moras, D.
Acta Crystallographica Section D 62
(Pt. 10): 1208-1217.
October 2006
Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases.
Bandapalli, O.R., Geheeb, M., Kobelt, D., Kuehnle, K., Elezkurtaj, S., Herrmann, J., Gressner, A.M., Weiskirchen, R., Beule, D., Blüthgen, N., Herzel, H., Franke, C. and Brand, K.
International Journal of Cancer 118
: 74-89.
1 January 2006
Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo.
Bannon, J.H., Fichtner, I., O'Neill, A., Pampillon, C., Sweeney, N.J., Strohfeldt, K., Watson, R.W., Tacke, M. and McGee, M.M.
British Journal of Cancer 97
(9): 1234-1241.
5 November 2007
In contrast to Western diet, a plant-based, high-fat, low-sugar diet does not exacerbate retinal endothelial injury in streptozotocin-induced diabetes.
Barakat, A., Nakao, S., Zandi, S., Sun, D., Schmidt-Ullrich, R., Hayes, K.C. and Hafezi-Moghadam, A.
FASEB Journal 33
(9): 10327-10338.
September 2019
Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D., Hörtenhuber, M., Balwierz, P.J., Zehnder, T., Mukarram, A.K., Nepal, C., Várnai, C., Hadzhiev, Y., Jimenez-Gonzalez, A., Li, N., Wragg, J., D'Orazio, F.M., Relic, D., Pachkov, M., Díaz, N., Hernández-Rodríguez, B., Chen, Z., Stoiber, M., Dong, M., Stevens, I., Ross, S.E., Eagle, A., Martin, R., Obasaju, O., Rastegar, S., McGarvey, A.C., Kopp, W., Chambers, E., Wang, D., Kim, H.R., Acemel, R.D., Naranjo, S., Łapiński, M., Chong, V., Mathavan, S., Peers, B., Sauka-Spengler, T., Vingron, M., Carninci, P., Ohler, U., Lacadie, S.A., Burgess, S.M., Winata, C., van Eeden, F., Vaquerizas, J.M., Gómez-Skarmeta, J.L., Onichtchouk, D., Brown, B.J., Bogdanovic, O., van Nimwegen, E., Westerfield, M., Wardle, F.C, Daub, C.O., Lenhard, B. and Müller, F.
Nature Genetics 54
(7): 1037-1050.
July 2022
Dynamics of the ligand binding domain layer during AMPA receptor activation.
Baranovic, J., Chebli, M., Salazar, H., Carbone, A.L., Faelber, K., Lau, A.Y., Daumke, O. and Plested, A.J.R.
Biophysical Journal 110
(4): 896-911.
23 February 2016
Subsequent malignancies among long-term survivors of Hodgkin lymphoma and non-Hodgkin lymphoma: a pooled analysis of German cancer registry data (1990-2012).
Baras, N., Dahm, S., Haberland, J., Janz, M., Emrich, K., Kraywinkel, K. and Salama, A.
British Journal of Haematology 177
(2): 226-242.
April 2017
Crystal structure of Escherichia coli phage HK620 tailspike: podoviral tailspike endoglycosidase modules are evolutionarily related.
Barbirz, S., Mueller, J.J., Uetrecht, C., Clark, A.J., Heinemann, U. and Seckler, R.
Molecular Microbiology 69
(2): 303-316.
July 2008
PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries.
Barbosa-Silva, A., Fontaine, J.F., Donnard, E.R., Stussi, F., Ortega, J.M. and Andrade-Navarro, M.A.
BMC Bioinformatics 12
(1): 435.
9 November 2011
Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.
Barettino, D., Bugge, T.H., Bartunek, P., Vivanco Ruiz, M.D., Sonntag-Buck, V., Beug, H., Zenke, M. and Stunnenberg, H.G.
EMBO Journal 12
(4): 1343-1354.
April 1993
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
Bargou, R.C., Emmerich, F., Krappmann, D., Bommert, K., Mapara, M.Y., Arnold, W., Royer, H.D., Grinstein, E., Greiner, A., Scheidereit, C. and Doerken, B.
Journal of Clinical Investigation 100
(12): 2961-2969.
15 December 1997
Characterization of a novel Hodgkin cell-line, HD-MyZ, HD-Myr, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.
Bargou, R.C., Mapara, M.Y., Zugck, C., Daniel, P.T., Pawlita, M., Doehner, H. and Doerken, B.
Journal of Experimental Medicine 177
(5): 1257-1268.
1 May 1993
Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, R.C., Wagener, C., Bommert, K., Arnold, W., Daniel, P.T., Mapara, M.Y., Grinstein, E., Royer, H.D. and Doerken, B.
Journal of Experimental Medicine 183
(3): 1205-1213.
1 March 1996
Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.
Bargou, R.C., Wagener, C., Bommert, K., Mapara, M.Y., Daniel, P.T., Arnold, W., Dietel, M., Guski, H., Feller, A., Royer, H.D. and Doerken, B.
Journal of Clinical Investigation 97
(11): 2651-2659.
1 June 1996
Experimental observation of a fundamental length scale of waves in random media.
Barkhofen, S., Metzger, J.J., Fleischmann, R., Kuhl, U. and Stöckmann, H.J.
Physical Review Letters 111
(18): 183902.
1 November 2013
Co-regulation of two gene activities by tetracycline via a bidirectional promoter.
Baron, U., Freundlieb, S., Gossen, M. and Bujard, H.
Nucleic Acids Research 23
(17): 3605-3606.
11 September 1995
Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential.
Baron, U., Gossen, M. and Bujard, H.
Nucleic Acids Research 25
(14): 2723-2729.
15 July 1997
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Barone, M., Müller, M., Chiha, S., Ren, J., Albat, D., Soicke, A., Dohmen, S., Klein, M., Bruns, J., van Dinther, M., Opitz, R., Lindemann, P., Beerbaum, M., Motzny, K., Roske, Y., Schmieder, P., Volkmer, R., Nazaré, M., Heinemann, U., Oschkinat, H., Ten Dijke, P., Schmalz, H.G. and Kühne, R.
Proceedings of the National Academy of Sciences of the United States of America 117
(47): 29684-29690.
24 November 2020
OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation.
Barrera, M., Koob, S., Dikov, D., Vogel, F. and Reichert, A.S.
FEBS Letters 590
(19): 3309-3322.
October 2016
Cyclin D3: requirement for G1/S transition and high abundance in quiescent tissues suggest a dual role in proliferation and differentiation.
Bartkova, J., Lukas, J., Strauss, M. and Bartek, J.
Oncogene 17
(8): 1027-1037.
27 August 1998
Active promoters and insulators are marked by the centrosomal protein 190.
Bartkuhn, M., Straub, T., Herold, M., Herrmann, M., Rathke, C., Saumweber, H., Gilfillan, G.D., Becker, P.B. and Renkawitz, R.
EMBO Journal 28
(7): 877-888.
8 April 2009
Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H., Balogh, A., Yakoub, M., Homann, S., Markó, L., Höges, S., Tsvetkov, D., Krannich, A., Wundersitz, S., Avery, E.G., Haase, N., Kräker, K., Hering, L., Maase, M., Kusche-Vihrog, K., Grandoch, M., Fielitz, J., Kempa, S., Gollasch, M., Zhumadilov, Z., Kozhakhmetov, S., Kushugulova, A., Eckardt, K.U., Dechend, R., Rump, L.C., Forslund, S.K., Müller, D.N., Stegbauer, J. and Wilck, N.
Circulation 139
(11): 1407-1421.
12 March 2019
The Myb leucine zipper is essential for leukemogenicity of the v-Myb protein.
Bartunek, P., Karafiat, V., Dvorakova, M., Zahorova, V., Mandikova, S., Zenke, M. and Dvorak, M.
Oncogene 15
(24): 2939-2949.
11 December 1997
GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter.
Bartunek, P., Kralova, J., Blendinger, G., Dvorak, M. and Zenke, M.
Oncogene 22
(13): 1927-1935.
3 April 2003
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
Basheer, F., Giotopoulos, G., Meduri, E., Yun, H., Mazan, M., Sasca, D., Gallipoli, P., Marando, L., Gozdecka, M., Asby, R., Sheppard, O., Dudek, M., Bullinger, L., Döhner, H., Dillon, R., Freeman, S., Ottmann, O., Burnett, A., Russell, N., Papaemmanuil, E., Hills, R., Campbell, P., Vassiliou, G.S.. and Huntly, B.J.P.
Journal of Experimental Medicine 216
(4): 966-981.
1 April 2019
Enhancement of CRISPR-Cas9 induced precise gene editing by targeting Histone H2A-K15 ubiquitination.
Bashir, S., Dang, T., Rossius, J., Wolf, J. and Kuehn, R.
BMC Biotechnology 20
(1): 57.
23 October 2020
CD40 activity on mesenchymal cells negatively regulates OX40L to maintain bone marrow immune homeostasis under stress conditions.
Bassani, B., Tripodo, C., Portararo, P., Gulino, A., Botti, L., Chiodoni, C., Jachetti, E., Bolli, N., Ciciarello, M., Joehrens, K., Anagnostopoulos, I., Na, I.K., Curti, A., Colombo, M.P. and Sangaletti, S.
Frontiers in Immunology 12
: 662048.
18 May 2021
Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A., Malhan, D., Dumbani, M., Dahlmann, M., Stein, U. and Relógio, A.
Cancers 14
(14): 3458.
16 July 2022
Synergistic activity of bortezomib and HDACis in preclinical models of B-cell precursor acute lymphoblastic leukemia via modulation of p53, PI3K/AKT and NF-κB.
Bastian, L., Hof, J., Pfau, M., Fichtner, I., Eckert, C., Henze, G., Prada, J., von Stackelberg, A., Seeger, K. and Shalapour, S.
Clinical Cancer Research 19
(6): 1445-1457.
15 March 2013
Unblending of transcriptional condensates in human repeat expansion disease.
Basu, S., Mackowiak, S.D., Niskanen, H., Knezevic, D., Asimi, V., Grosswendt, S., Geertsema, H., Ali, S., Jerković, I., Ewers, H., Mundlos, S., Meissner, A., Ibrahim, D.M. and Hnisz, D.
Cell 181
(5): 1062-1079.
28 May 2020
Extraembryonic gut endoderm cells undergo programmed cell death during development.
Batki, J., Hetzel, S., Schifferl, D., Bolondi, A., Walther, M., Wittler, L., Grosswendt, S., Herrmann, B.G. and Meissner, A.
Nature Cell Biology 26
(6): 868-877.
June 2024
Transcriptional repression and activation in the same cell type of the human c-MYC promoter by the retinoblastoma gene protein: antagonisation of both effects by SV40 T antigen.
Batsche, E., Lipp, M. and Cremisi, C.
Oncogene 9
(8): 2235-2243.
August 1994
Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis.
Bauer, M.K.A., Schubert, A., Rocks, O. and Grimm, S.
Journal of Cell Biology 147
(7): 1493-1502.
27 December 1999
Feedback, mass conservation and reaction kinetics impact the robustness of cellular oscillations.
Baum, K., Politi, A.Z., Kofahl, B., Steuer, R. and Wolf, J.
PLoS Computational Biology 12
(12): e1005298.
27 December 2016
Analysis of correlation-based biomolecular networks from different omics data by fitting stochastic block models.
Baum, K., Rajapakse, J.C. and Azuaje, F.
F1000Research 8
: 465.
27 August 2019
Of gene expression and cell division time: a mathematical framework for advanced differential gene expression and data analysis.
Baum, K., Schuchhardt, J., Wolf, J. and Busse, D.
Cell Systems 9
(6): 569-579.
18 December 2019
State-of-the-art analytical methods of viral infections in human lung organoids.
Baumgardt, M., Hülsemann, M., Löwa, A., Fatykhova, D., Hoffmann, K., Kessler, M., Mieth, M., Hellwig, K., Frey, D., Langenhagen, A., Voss, A., Obermayer, B., Wyler, E., Dökel, S., Gruber, A.D., Tölch, U., Hippenstiel, S., Hocke, A.C. and Hönzke, K.
PLoS ONE 17
(12): e0276115.
20 December 2022
Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022.
Baumgartner, F., Baer, C., Bamopoulos, S.A., Ayoub, E., Truger, M., Meggendorfer, M., Lenk, M., Hoermann, G., Hutter, S., Müller, H., Walter, W., Mueller, M.L., Nadarajah, Ni., Blombery, P., Keller, U., Kern, W., Haferlach, C. and Haferlach, T.
Blood 143
(12): 1139-1156.
21 March 2024
Activation of gp130 signaling in T cells drives T(H)17-mediated multi-organ autoimmunity.
Baumgartner, F., Bamopoulos, S.A., Faletti, L., Hsiao, H.J., Holz, M., Gonzalez-Menendez, I., Solé-Boldo, L., Horne, A., Gosavi, S., Özerdem, C., Singh, N., Liebig, S., Ramamoorthy, S., Lehmann, M., Demel, U., Kühl, A.A., Wartewig, T., Ruland, J., Wunderlich, F.T., Schick, M., Walther, W., Rose-John, S., Haas, S., Quintanilla-Martinez, L., Feske, S., Ehl, S., Glauben, R. and Keller, U.
Science Signaling 17
(824): eadc9662.
20 February 2024
Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A., Zelarayan, L., Betney, R., Gehrke, C., Dunger, S., Noack, C., Busjahn, A., Huelsken, J., Taketo, M.M., Birchmeier, W., Dietz, R. and Bergmann, M.W.
Circulation Research 100
(9): 1353-1362.
11 May 2007
Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics.
Bayram, S., Razzaque, Y.S., Geisberger, S., Pietzke, M., Fürst, S., Vechiatto, C., Forbes, M., Mastrobuoni, G. and Kempa, S.
Frontiers in Molecular Biosciences 9
: 859787.
12 August 2022
Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M., Terkelsen, T., Bartels, A.S., Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G.I., Fang, X., Mann, M. and Moreira, J.M.A.
Gastroenterology 165
(1): 121-132.e5.
July 2023
PRC1-mediated gene silencing in pluripotent ES cells: function and evolution.
Becker, M., Mah, N., Zdzieblo, D., Li, X., Mer, A.S., Andrade-Navarro, M.A. and Mueller, A.M.
Epigenetics and Human Health 2015
: 141-166.
18 November 2014
Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM.
Becker, M., Sommer, A., Kraetzschmar, J.R., Seidel, H., Pohlenz, H.D. and Fichtner, I.
Molecular Cancer Therapeutics 4
: 151-170.
1 January 2005
Direct homo- and hetero-interactions of MeCP2 and MBD2.
Becker, A., Allmann, L., Hofstätter, M., Casa, V., Weber, P., Lehmkuhl, A., Herce, H.D. and Cardoso, M.C.
PLoS ONE 8
(1): e53730.
15 January 2013
Poly(ADP-ribosyl)ation of Methyl CpG binding domain protein 2 regulates chromatin structure.
Becker, A., Zhang, P., Allmann, L., Meilinger, D., Bertulat, B., Eck, D., Hofstaetter, M., Bartolomei, G., Hottiger, M.O., Schreiber, V., Leonhardt, H. and Cardoso, M.C.
Journal of Biological Chemistry 291
(10): 4873-4881.
4 March 2016
Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia.
Becker, H., Pfeifer, D., Ihorst, G., Pantic, M., Wehrle, J., Rüter, B.H., Bullinger, L., Hackanson, B., Germing, U., Kuendgen, A., Platzbecker, U., Döhner, K., Ganser, A., Hagemeijer, A., Wijermans, P.W., Döhner, H., Duyster, J. and Lübbert, M.
Annals of Hematology 99
(7): 1551-1560.
July 2020
The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration.
Becker, M.S., Müller, P.M., Bajorat, J., Schroeder, A., Giaisi, M., Amin, E., Ahmadian, M.R., Rocks, O., Köhler, R., Krammer, P.H. and Li-Weber, M.
Oncotarget 7
(32): 51908-51921.
9 August 2016
The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression.
Becker, M.S., Schmezer, P., Breuer, R., Haas, S.F., Essers, M.A., Krammer, P.H. and Li-Weber, M.
Cell Death & Disease 5
: e1000.
January 2014
A model of the mammalian circadian oscillator including the REV-ERBalpha module.
Becker-Weimann, S., Wolf, J., Kramer, A. and Herzel, H.
Genome Informatics 15
(1): 3-12.
2004
Cancer evolution: mathematical models and computational inference.
Beerenwinkel, N., Schwarz, R.F., Gerstung, M. and Markowetz, F.
Systematic Biology 64
(1): e1-e25.
January 2015
Oligomeric structure of mammalian purine nucleoside phosphorylase in solution determined by analytical ultracentrifugation.
Behlke, J., Koellner, G. and Bzowska, A.
Zeitschrift fuer Naturforschung C, A Journal of Biosciences 60
(11-12): 927-931.
November 2005
Protein crystallization with and without precipitants.
Behlke, J., Marg, A. and Paeschke, M.
Journal of Applied Crystallography 30
(5/1): 559-560.
1 October 1997
Enhanced resolution of sedimentation coefficient distribution profiles by extrapolation to infinite time.
Behlke, J. and Ristau, O.
European Biophysics Journal 39
(3): 449-455.
February 2010
Molecular mass determination by sedimentation velocity experiments and direct fitting of the concentration profiles.
Behlke, J. and Ristau, O.
Biophysical Journal 72
(1): 428-434.
January 1997
Self-association of adrenodoxin studied by using analytical ultracentrifugation.
Behlke, J., Ristau, O., Mueller, E.C., Hannemann, F. and Bernhardt, R.
Biophysical Chemistry 125
(1): 159-165.
January 2007
Loss of tumourigenicity of stably ERbeta-transfected MCF-7 breast cancer cells.
Behrens, D., Gill, J.H. and Fichtner, I.
Molecular and Cellular Endocrinology 274
(1-2): 19-29.
15 August 2007
The mTOR pathway inhibitor RAD001 (everolimus) is highly efficacious in tamoxifen-sensitive and -resistant breast cancer xenografts.
Behrens, D., Lykkesfeldt, A.E. and Fichtner, I.
Targeted Oncology 2
(3): 135-144.
July 2007
Control of beta-catenin signaling in tumor development.
Behrens, J.
Annals of the New York Academy of Sciences 910
: 21-35.
June 2000
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Behrens, J., Jerchow, B.A., Wuertele, M., Grimm, J., Asbrand, C., Wirtz, R., Kuehl, M., Wedlich, D. and Birchmeier, W.
Science 280
(5363): 596-599.
24 April 1998
Functional interaction of beta-catenin with the transcription factor LEF-1.
Behrens, J., von Kries, J.P., Kuehl, M., Bruhn, L., Wedlich, D., Grosschedl, R. and Birchmeier, W.
Nature 382
(6592): 638-642.
15 August 1996
Establishment and thorough characterization of xenograft (PDX) models derived from patients with pancreatic cancer for molecular analyses and chemosensitivity testing.
Behrens, D., Pfohl, U., Conrad, T., Becker, M., Brzezicha, B., Büttner, B., Wagner, S., Hallas, C., Lawlor, R., Khazak, V., Linnebacher, M., Wartmann, T., Fichtner, I., Hoffmann, J., Dahlmann, M. and Walther, W.
Cancers 15
(24): 5753.
8 December 2023
Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K., Goergen, H., Hitz, F., Zijlstra, J.M., Greil, R., Markova, J., Sasse, S., Fuchs, M., Topp, M.S., Soekler, M., Mathas, S., Meissner, J., Wilhelm, M., Koch, P., Lindemann, H.W., Schalk, E., Semrau, R., Kriz, J., Vieler, T., Bentz, M., Lange, E., Mahlberg, R., Hassler, A., Vogelhuber, M., Hahn, D., Mezger, J., Krause, S.W., Skoetz, N., Böll, B., von Tresckow, B., Diehl, V., Hallek, M., Borchmann, P., Stein, H., Eich, H. and Engert, A.
Lancet 385
(9976): 1418-1427.
11 April 2015
Structural identification of the VPS18 β-propeller reveals a critical role in the HOPS complex stability and function.
Behrmann, H., Lürick, A., Kuhlee, A., Kleine Balderhaar, H., Bröcker, C., Kümmel, D., Engelbrecht-Vandré, S., Gohlke, U., Raunser, S., Heinemann, U. and Ungermann, C.
Journal of Biological Chemistry 289
(48): 33503-33512.
28 November 2014
Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer.
Bei, Y., Brame, Luca, Kirchner, M., Fritsche-Guenther, R., Kunz, S., Bhattacharya, A., Rusu, M.C., Gürgen, D., Dubois, F.P.B., Köppke, J.K.C., Proba, J., Wittstruck, N., Sidorova, O.A., Chamorro González, R., Dorado Garcia, H., Brückner, L., Xu, R., Giurgiu, M., Rodriguez-Fos, E., Yu, Q., Spanjaard, B., Koche, R.P., Schmitt, C.A., Schulte, J.H., Eggert, A., Haase, K., Kirwan, J., Hagemann, A.I., Mertins, P., Dörr, J.R. and Henssen, A.G.
Cancer Discovery 14
(3): 492-507.
1 March 2024
Claudin-targeted suicide gene therapy for claudin-overexpressing tumor cells by using modified clostridium perfringens enterotoxin (CPE).
Beier, L.S., Piontek, J., Piontek, A., Protze, J., Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521
(3): 173-188.
23 June 2022
Upgrade of an optical navigation system with a permanent electromagnetic position control : A first step towards "navigated control" for liver surgery.
Beller, S., Eulenstein, S., Lange, T., Huenerbein, M. and Schlag, P.M.
Journal of Hepato-Biliary-Pancreatic Surgery 16
(2): 165-170.
March 2009
A new measure to assess the difficulty of liver resection.
Beller, S., Eulenstein, S., Lange, T., Niederstrasser, M., Huenerbein, M. and Schlag, P.M.
European Journal of Surgical Oncology 35
(1): 59-64.
January 2009
Feasibility of navigated resection of liver tumors using multiplanar visualization of intraoperative 3-dimensional ultrasound data.
Beller, S., Huenerbein, M., Eulenstein, S., Lange, T. and Schlag, P.M.
Annals of Surgery 246
(2): 288-294.
August 2007
Image-guided surgery of liver metastases by three-dimensional ultrasound-based optoelectronic navigation.
Beller, S., Huenerbein, M., Lange, T., Eulenstein, S., Gebauer, B. and Schlag, P.M.
British Journal of Surgery 94
(7): 866-875.
July 2007
Hat die palliative Resektion bei gastrointestinalen Tumoren noch einen Stellenwert? [Significance of palliative resection of gastrointestinal tumors.].
Beller, S. and Schlag, P.M.
Chirurg 77
: 219-226.
March 2006
CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.
Beltinger, C., Kurz, E., Boehler, T., Schrappe, M., Ludwig, W.D. and Debatin, K.M.
Blood 91
(10): 3943-3951.
15 May 1998
Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly.
Belz, K., Schoeneberger, H., Wehner, S., Weigert, A., Boenig, H., Klingebiel, T., Fichtner, I. and Fulda, S.
Blood 124
(2): 240-250.
10 July 2014
Impact of patient- and disease-specific factors on SLNB in breast cancer patients. Are current guidelines justified?
Bembenek, A., Fischer, J., Albrecht, H., Kemnitz, E., Gretschel, S., Schneider, U., Dresel, S. and Schlag, P.M.
World Journal of Surgery 31
(2): 267-275.
February 2007
Sentinel-Node-Biopsie : Definition, historische Entwicklung und methodisches Vorgehen.
Bembenek, A., Gretschel, S., Ulmer, C., Bayraktar, S. and Schlag, P.M.
Onkologe 9
(6): 599-610.
June 2003
Sentinel Lymph Node beim kolorektalen Karzinom [Sentinel lymph node biopsy in colorectal carcinoma].
Bembenek, A., Gretschel, S., Ulmer, C. and Schlag, P.M.
Chirurg 75
(8): 761-766.
1 January 2004
Presence of mature DC-Lamp(+) dendritic cells in sentinel and non-sentinel lymph nodes of breast cancer patients.
Bembenek, A., Li, J., Loddenkemper, C., Kemmner, W., Stein, H., Wernecke, K.D. and Schlag, P.M.
European Journal of Surgical Oncology 34
(5): 514-518.
May 2008
Sentinel lymph node biopsy in rectal cancer - not yet ready for routine clinical use.
Bembenek, A., Rau, B., Moesta, T., Markwardt, J., Ulmer, C., Gretschel, S., Schneider, U., Slisow, W. and Schlag, P.M.
Surgery 135
(5): 498-505.
May 2004
Detection of lymph node micrometastases and isolated tumor cells in sentinel and nonsentinel lymph nodes of colon cancer patients.
Bembenek, A., Schneider, U., Gretschel, S., Fischer, J. and Schlag, P.M.
World Journal of Surgery 29
: 1172-1175.
11 August 2005
Optimierung des Staging beim Kolonkarzinom durch Sentinel-Lymphknoten-Biopsie. Aktuelle Aspekte [Optimization of staging in colon cancer using sentinel lymph node biopsy].
Bembenek, A., Schneider, U., Gretschel, S., Ulmer, C. and Schlag, P.M.
Chirurg 76
(1): 58-67.
January 2005
Sentinel lymph node biopsy in colon cancer: A prospective multicenter trial.
Bembenek, A.E., Rosenberg, R., Wagler, E., Gretschel, S., Sendler, A., Siewert, J.R., Naehrig, J., Witzigmann, H., Hauss, J., Knorr, C., Dimmler, A., Groene, J., Buhr, H.J., Haier, J., Herbst, H., Tepel, J., Siphos, B., Kleespies, A., Koenigsrainer, A., Stoecklein, N.H., Horstmann, O., Gruetzmann, R., Imdahl, A., Svoboda, D., Wittekind, C., Schneider, W., Wernecke, K.D. and Schlag, P.M.
Annals of Surgery 245
(6): 858-863.
June 2007
A kinome of 2600 in the ciliate Paramecium tetraurelia.
Bemm, F., Schwarz, R., Foerster, F. and Schultz, J.
FEBS Letters 583
(22): 3589-3592.
19 November 2009
Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry.
Ben Hamza, A., Welters, C., Stadler, S., Brüggemann, M., Dietze, K., Brauns, O., Brümmendorf, T.H., Winkler, T.H., Bullinger, L., Blankenstein, T., Rosenberger, L., Leisegang, M., Kammertöns, T., Herr, W., Moosmann, A., Strobel, J., Hackstein, H., Dornmair, K., Beier, F. and Hansmann, L.
Blood 143
(14): 1365-1378.
4 April 2024
gen.ethix. Multimediales Online-Spiel zum aktuellen Bioethik-Diskurs.
Ben Salem, A.
BBB CampusNews
: 2.
1 January 2004
Modeling Wnt/β-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions.
Benary, U., Kofahl, B., Hecht, A. and Wolf, J.
Frontiers in Physiology 4
: 21.
25 February 2013
Disentangling pro-mitotic signaling during cell cycle progression using time-resolved single-cell imaging.
Benary, M., Bohn, S., Lüthen, M., Nolis, I.K., Blüthgen, N. and Loewer, A.
Cell Reports 31
(2): 107514.
14 April 2020
Leveraging large language models for decision support in personalized oncology.
Benary, M., Wang, X.D., Schmidt, M., Soll, D., Hilfenhaus, G., Nassir, M., Sigler, C., Knödler, M., Keller, U., Beule, D., Keilholz, U., Leser, U. and Rieke, D.T.
JAMA Network Open 6
(11): e2343689.
November 2023
Mathematical modelling of promoter occupancies in MYC-dependent gene regulation.
Benary, U., Wolf, E. and Wolf, J.
Genomics and Computational Biology 3
(2): e54.
2017
Controlling nuclear NF-κB dynamics by β-TrCP-insights from a computational model.
Benary, U. and Wolf, J.
Biomedicines 7
(2): 40.
27 May 2019
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.
Bendle, G.M., Linnemann, C., Hooijkaas, A.I., Bies, L., de Witte, M.A., Jorritsma, A., Kaiser, A.D.M., Pouw, N., Debets, R., Kieback, E., Uckert, W., Song, J.Y., Haanen, J.B.A.G. and Schumacher, T.N.M.
Nature Medicine 16
(5): 565-570, 1p following 570.
May 2010
The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias.
Bene, M.C., Bernier, M., Casasnovas, R.O., Castoldi, G., Knapp, W., Lanza, F., Ludwig, W.D., Matutes, E., Orfao, A., Sperling, C. and van't Veer, M.B.
Blood 92
(2): 596-599.
15 July 1998
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia.
Beneyto-Calabuig, S., Merbach, A.K., Kniffka, J.A., Antes, M., Szu-Tu, C., Rohde, C., Waclawiczek, A., Stelmach, P., Gräßle, S., Pervan, P., Janssen, M., Landry, J.J.M., Benes, V., Jauch, A., Brough, M., Bauer, M., Besenbeck, B., Felden, J., Bäumer, S., Hundemer, M., Sauer, T., Pabst, C., Wickenhauser, C., Angenendt, L., Schliemann, C., Trumpp, A., Haas, S., Scherer, M., Raffel, S., Müller-Tidow, C. and Velten, L.
Cell Stem Cell 30
(5): 706-721.
4 May 2023
The c-Myc/miR17-92/PTEN axis tunes PI3K activity to control expression of recombination activating genes in early B cell development.
Benhamou, D., Labi, V., Getahun, A., Benchetrit, E., Dowery, R., Rajewsky, K., Cambier, J.C. and Melamed, D.
Frontiers in Immunology 9
: 2715.
November 2018
A c-Myc/miR17-92/Pten axis controls PI3K-mediated positive and negative selection in B cell development and reconstitutes CD19 deficiency.
Benhamou, D., Labi, V., Novak, R., Dai, I., Shafir-Alon, S., Weiss, A., Gaujoux, R., Arnold, R., Shen-Orr, S.S., Rajewsky, K. and Melamed, D.
Cell Reports 16
(2): 419-431.
12 July 2016
Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues.
Benndorf, R., Gilmont, R.R., Hirano, S., Ransom, R.F., Jungblut, P.R., Bommer, M., Goldman, J.E. and Welsh, M.J.
Cell Stress & Chaperones 23
(5): 813-826.
September 2018
Therapie eines Zenker'schen Divertikels [Therapy of Zenker's divertikulum].
Benter, T., Kretzschmar, A., Reich, G., Papadopoulos, S., Kluhs, L., Ludwig, W.D. and Doerken, B.
Medizinische Klinik 97
(1): 44-45.
January 2002
Anatomical variations in the internal jugular veins of cancer patients affecting central venous access. Anatomical variation of the internal jugular vein.
Benter, T., Teichgraeber, U.K., Kluehs, L., Papadopoulos, S., Koehne, C.H., Felix, R. and Doerken, B.
Ultraschall in der Medizin 22
(1): 23-26.
February 2001
Using DNA sequencing data to quantify T cell fraction and therapy response.
Bentham, R., Litchfield, K., Watkins, T.B.K., Lim, E.L., Rosenthal, R., Martínez-Ruiz, C., Hiley, C.T., Bakir, M.A., Salgado, R., Moore, D.A., Jamal-Hanjani, M., Swanton, C. and McGranahan, N.
Nature 597
(7877): 555-560.
23 September 2021
The Cambridge jet algorithm: Features and applications.
Bentvelsen, S. and Meyer, I.M.
European Physical Journal C 4
(4): 623-629.
July 1998
Isolation of eosinophils from the lamina propria of the murine small intestine.
Berek, C., Beller, A. and Chu, V.T.
Methods in Molecular Biology 1422
: 213-221.
2016
Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia.
Berenstein, R., Blau, I.W., Suckert, N., Baldus, C., Pezzutto, A., Dörken, B. and Blau, O.
Journal of Experimental & Clinical Cancer Research 34
(1): 55.
22 May 2015
Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region.
Berenstein, R., Blau, O., Nogai, A., Waechter, M., Slonova, E., Schmidt-Hieber, M., Kunitz, A., Pezzutto, A., Doerken, B. and Blau, I.W.
BMC Cancer 15
(1): 68.
18 February 2015
Multiple myeloma cells modify VEGF/IL-6 levels and osteogenic potential of bone marrow stromal cells via Notch/miR-223.
Berenstein, R., Nogai, A., Waechter, M., Blau, O., Kuehnel, A., Schmidt-Hieber, M., Kunitz, A., Pezzutto, A., Dörken, B. and Blau, I.W.
Molecular Carcinogenesis 55
(12): 1927-1939.
December 2016
Structure of the Yersinia injectisome in intracellular host cell phagosomes revealed by cryo FIB electron tomography.
Berger, C., Ravelli, R.B.G., López-Iglesias, C., Kudryashev, M., Diepold, A. and Peters, P.J.
Journal of Structural Biology 213
(1): 107701.
March 2021
Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.
Bergman, A.M., Adema, A.D., Balzarini, J., Bruheim, S., Fichtner, I., Noordhuis, P., Fodstad, O., Myhren, F., Sandvold, M.L., Hendriks, H.R. and Peters, G.J.
Investigational New Drugs 29
(3): 456-466.
June 2011
YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification.
Bergmann, S., Royer-Pokora, B., Fietze, E., Juerchott, K., Hildebrandt, B., Trost, D., Leenders, F., Claude, J.C., Theuring, F., Bargou, R., Dietel, M. and Royer, H.D.
Cancer Research 65
(10): 4078-4087.
16 May 2005
Modelling the DNA topology: the effect of the loop bending on G-quadruplex stability.
Bergues-Pupo, A.E., Falo, F. and Fiasconaro, A.
Journal of Statistical Mechanics: Theory and Experiment 2019
(9): 094004.
2 September 2019
Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Berlak, M., Tucker, E., Dorel, M., Winkler, A., McGearey, A., Rodriguez-Fos, E., da Costa, B.M., Barker, K., Fyle, E., Calton, E., Eising, S., Ober, K., Hughes, D., Koutroumanidou, E., Carter, P., Stankunaite, R., Proszek, P., Jain, N., Rosswog, C., Dorado-Garcia, H., Molenaar, J.J., Hubank, M., Barone, G., Anderson, J., Lang, P., Deubzer, H.E., Künkele, A., Fischer, M., Eggert, A., Kloft, C., Henssen, A.G., Boettcher, M., Hertwig, F., Blüthgen, N., Chesler, L. and Schulte, J.H.
Molecular Cancer 21
(1): 126.
10 June 2022
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19.
Bernardes, J.P., Mishra, N., Tran, F., Bahmer, T., Best, L., Blase, J.I., Bordoni, D., Franzenburg, J., Geisen, U., Josephs-Spaulding, J., Köhler, P., Künstner, A., Rosati, E., Aschenbrenner, A.C., Bacher, P., Baran, N., Boysen, T., Brandt, B., Bruse, N., Dörr, J., Dräger, A., Elke, G., Ellinghaus, D., Fischer, J., Forster, M., Franke, A., Franzenburg, S., Frey, N., Friedrichs, A., Fuß, J., Glück, A., Hamm, J., Hinrichsen, F., Hoeppner, M.P., Imm, S., Junker, R., Kaiser, S., Kan, Y.H., Knoll, R., Lange, C., Laue, G., Lier, C., Lindner, M., Marinos, G., Markewitz, R., Nattermann, J., Noth, R., Pickkers, P., Rabe, K.F., Renz, A., Röcken, C., Rupp, J., Schaffarzyk, A., Scheffold, A., Schulte-Schrepping, J., Schunk, D., Skowasch, D., Ulas, T., Wandinger, K.P., Wittig, M., Zimmermann, J., Busch, H., Hoyer, B.F., Kaleta, C., Heyckendorf, J., Kox, M., Rybniker, J., Schreiber, S., Schultze, J.L. and Rosenstiel, P.
Immunity 53
(6): 1296-1314.
15 December 2020
Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer.
Berndt, N., Egners, A., Mastrobuoni, G., Vvedenskaya, O., Fragoulis, A., Dugourd, A., Bulik, S., Pietzke, M., Bielow, C., van Gassel, R., Olde Damink, S.W., Erdem, M., Saez-Rodriguez, J., Holzhütter, H.G., Kempa, S. and Cramer, T.
British Journal of Cancer 122
(2): 233-244.
21 January 2020
Quinols as novel therapeutic agents. 2.(1) 4-(1-arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.
Berry, J.M., Bradshaw, T.D., Fichtner, I., Ren, R., Schwalbe, C.H., Wells, G., Chew, E.H., Stevens, M.F. and Westwell, A.D.
Journal of Medicinal Chemistry 48
: 639-644.
27 January 2005
Proteomics of xenografted human breast cancer indicates novel targets related to tamoxifen resistance.
Besada, V., Diaz, M., Becker, M., Ramos, Y., Castellanos-Serra, L. and Fichtner, I.
Proteomics 6
(3): 1038-1048.
February 2006
Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
Besser, D., Bardelli, A., Didichenko, S., Thelen, M., Comoglio, P.M., Ponzetto, C. and Nagamine, Y.
Oncogene 14
(6): 705-711.
13 February 1997
A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.
Besser, D., Bromberg, J.F., Darnell, J.E. and Hanafusa, H.
Molecular and Cellular Biology 19
(2): 1401-1409.
February 1999
DNA methylation inhibits transcription by RNA polymerase III of a tRNA gene, but not of a 5S rRNA gene.
Besser, D., Goetz, F., Schulze-Forster, K., Wagner, H., Kroeger, H. and Simon, D.
FEBS Letters 269
(2): 358-362.
3 September 1990
Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts.
Besser, D., Presta, M. and Nagamine, Y.
Cell Growth & Differentiation 6
(8): 1009-1017.
August 1995
Urokinase-type plasminogen activator gene regulation by polyomavirus middle-T antigen.
Besser, D., Urich, M., Sakaue, M., Messerschmitt, A., Ballmer-Hofer, K. and Nagamine, Y.
Oncogene 11
(11): 2383-2391.
7 December 1995
Signal transduction and the u-PA/u-PAR system.
Besser, D., Verde, P., Nagamine, Y. and Blasi, F.
Fibrinolysis 10
(4): 215-237.
July 1996
Expression of nodal, lefty-A, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.
Besser, D.
Journal of Biological Chemistry 279
(43): 45076-45084.
1 January 2004
Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune, M.T., Gee, M.H., Bunse, M., Lee, M.S., Gschweng, E.H., Pagadala, M.S., Zhou, J., Cheng, D., Heath, J.R., Kohn, D.B., Kuhns, M.S., Uckert, W. and Baltimore, D.
eLife 5
: e19095.
8 November 2016
Molecular dynamics simulations of the 136 unique tetranucleotide sequences of DNA oligonucleotides.
Beveridge, D.L., Barreiro, G., Byun, S.K., Case, D.A., Cheatham, T.E., Dixit, S.B., Giudice, E., Lankas, F., Lavery, R., Maddocks, J.H., Osman, R., Seibert, E., Sklenar, H., Stoll, G., Thayer, K.M., Varnai, P. and Young, M.A.
Biophysical Journal 87
(6): 3799-3813.
December 2004
Clinical features and outcome of children with first marrow relapse of acute lymphoblastic leukemia expressing BCR-ABL fusion transcripts.
Beyermann, B., Agthe, A.G., Adams, H.P., Seeger, K., Linderkamp, C., Goetze, G., Ludwig, W.D. and Henze, G.
Blood 87
(4): 1532-1538.
15 February 1996
Conformation and stability of the Streptococcus pyogenes pSM19035-encoded site-specific beta recombinase, and identification of a folding intermediate.
Bhardwaj, A., Welfle, K., Misselwitz, R., Ayora, S., Alonso, J.C. and Welfle, H.
Biological Chemistry 387
(5): 525-533.
May 2006
Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.
Bhaskara, R.M., Grumati, P., Garcia-Pardo, J., Kalayil, S., Covarrubias-Pinto, A., Chen, W., Kudryashev, M., Dikic, I. and Hummer, G.
Nature Communications 10
(1): 2370.
30 May 2019
DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis.
Bhonde, M.R., Hanski, M.L., Budczies, J., Cao, M., Gillissen, B., Moorthy, D., Simonetta, F., Scheruebl, H., Truss, M., Hagemeier, C., Mewes, H.W., Daniel, P.T., Zeitz, M. and Hanski, C.
Journal of Biological Chemistry 281
: 8675-8685.
31 March 2006
The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein.
Bhonde, M.R., Hanski, M.L., Magrini, R., Moorthy, D., Mueller, A., Sausville, E.A., Kohno, K., Wiegand, P., Daniel, P.T., Zeitz, M. and Hanski, C.
Oncogene 24
: 148-156.
6 January 2005
Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.
Bhonde, M.R., Hanski, M.L., Notter, M., Gillissen, B.F., Daniel, P.T., Zeitz, M. and Hanski, C.
Oncogene 25
: 165-175.
12 January 2006
Replicative aging and differentiation potential of human adipose tissue-derived mesenchymal stromal cells expanded in pooled human or fetal bovine serum.
Bieback, K., Hecker, A., Schlechter, T., Hofmann, I., Brousos, N., Redmer, T., Besser, D., Klueter, H., Mueller, A.M. and Becker, M.
Cytotherapy 14
(5): 570-583.
May 2012
SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
Biederstädt, A., Hassan, Z., Schneeweis, C., Schick, M., Schneider, L., Muckenhuber, A., Hong, Y., Siegers, G., Nilsson, L., Wirth, M., Dantes, Z., Steiger, K., Schunck, K., Langston, S., Lenhof, H.P., Coluccio, A., Orben, F., Slawska, J., Scherger, A., Saur, D., Müller, S., Rad, R., Weichert, W., Nilsson, J., Reichert, M., Schneider, G. and Keller, U.
Gut 69
(8): 1472-1482.
August 2020
Skin-resident innate lymphoid cells converge on a pathogenic effector state.
Bielecki, P., Riesenfeld, S.J., Hütter, J.C., Torlai Triglia, E., Kowalczyk, M.S., Ricardo-Gonzalez, R.R., Lian, M., Amezcua Vesely, M.C., Kroehling, L., Xu, H., Slyper, M., Muus, C., Ludwig, L.S., Christian, E., Tao, L., Kedaigle, A.J., Steach, H.R., York, A.G., Skadow, M.H., Yaghoubi, P., Dionne, D., Jarret, A., McGee, H.M., Porter, C.B.M., Licona-Limón, P., Bailis, W., Jackson, R., Gagliani, N., Gasteiger, G., Locksley, R.M., Regev, A. and Flavell, R.A.
Nature 592
(7852): 128-132.
1 April 2021
On mass ambiguities in high-resolution shotgun lipidomics.
Bielow, C., Mastrobuoni, G., Orioli, M. and Kempa, S.
Analytical Chemistry 89
(5): 2986-2994.
7 March 2017
Radioimmunotherapy using 131I-rituximab in patients with advanced stage B-cell non-Hodgkin's lymphoma: initial experience.
Bienert, M., Reisinger, I., Srock, S., Humplik, B.I., Reim, C., Kroessin, T., Avril, N., Pezzutto, A. and Munz, D.L.
European Journal of Nuclear Medicine and Molecular Imaging 32
: 1225-1233.
1 January 2005
Crystal structure of NblA from Anabaena sp. PCC 7120, a small protein playing a key role in phycobilisome degradation.
Bienert, R., Baier, K., Volkmer, R., Lockau, W. and Heinemann, U.
Journal of Biological Chemistry 281
(8): 5216-5223.
24 February 2006
Single-stranded DNA bound to bacterial cold-shock proteins: preliminary crystallographic and Raman analysis.
Bienert, R., Zeeb, M., Dostal, L., Feske, A., Magg, C., Max, K., Welfle, H., Balbach, J. and Heinemann, U.
Acta Crystallographica Section D 60
(4): 755-757.
1 January 2004
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer.
Bigl, M., Jandrig, B., Horn, L.C. and Eschrich, K.
Biochemical and Biophysical Research Communications 377
(2): 720-724.
12 December 2008
In vitro activity and mechanism of action of a duplex and multidrug of ethynylcytidine and 5-fluorodeoxyuridine.
Bijnsdorp, I., Schwendener, R., Schott, H., Schott, S., Fichtner, I., Honeywell, R., Losekoot, N., Laan, A. and Peters, G.J.
Nucleic Acids Symposium Series 52
: 651.
8 September 2008
Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.
Bijnsdorp, I.V., Schwendener, R.A., Schott, H., Fichtner, I., Smid, K., Laan, A.C., Schott, S., Losekoot, N., Honeywell, R.J. and Peters, G.J.
Investigational New Drugs 29
(2): 248-257.
April 2011
In vivo and in vitro activity and mechanism of action of the multidrug cytarabine-L-glycerylyl-fluorodeoxyuridine.
Bijnsdorp, I.V., Schwendener, R.A., Schott, H., Fichtner, I., Smid, K., Schott, S., Laan, A.C. and Peters, G.J.
Nucleosides Nucleotides & Nucleic Acids 26
(10-12): 1619-1624.
5 December 2007
Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.
Bilic, I., Koesters, C., Unger, B., Sekimata, M., Hertweck, A., Maschek, R., Wilson, C.B. and Ellmeier, W.
Nature Immunology 7
(4): 392-400.
April 2006
Hormonal induction of functional differentiation and mammary-derived growth inhibitor expression in cultured mouse mammary gland explants.
Binas, B., Spitzer, E., Zschiesche, W., Erdmann, B., Kurtz, A., Mueller, T., Niemann, C., Blenau, W. and Grosse, R.
In Vitro Cellular & Developmental Biology 28A
(9-10): 625-634.
September 1992
Tailoring sparse multivariable regression techniques for prognostic single-nucleotide polymorphism signatures.
Binder, H., Benner, A., Bullinger, L. and Schumacher, M.
Statistics in Medicine 32
(10): 1778-91.
10 May 2013
Identification and functional characterization of hypoxia-induced endoplasmic reticulum stress regulating lncRNA (HypERlnc) in pericytes.
Bischoff, F.C., Werner, A., John, D., Boeckel, J.-N., Melissari, M.-T., Grote, P., Glaser, S.F., Demolli, S., Uchida, S., Michalik, K.M., Meder, B., Katus, H.A., Haas, J., Chen, W., Pullamsetti, S.S., Seeger, W., Zeiher, A.M., Dimmeler, S. and Zehendner, C.M.
Circulation Research 121
(4): 368-375.
4 August 2017
The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing.
Bischoff, N., Wimberger, S., Kuehn, R., Laugesen, A., Turan, V., Larsen, B.D., Sørensen, C.S., Helin, K., Bennett, E.P., Maresca, M. and Brakebusch, C.
Gene and Genome Editing 5
: 100023.
June 2023
Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R., Dickinson, M., Purtill, D., Barba, P., Santoro, A., Hamad, N., Kato, K., Sureda, A., Greil, R., Thieblemont, C., Morschhauser, F., Janz, M., Flinn, I., Rabitsch, W., Kwong, Y.L., Kersten, M.J, Minnema, M.C., Holte, H., Chan, E.H.L., Martinez-Lopez, J., Müller, A.M.S., Maziarz, R.T., McGuirk, J.P., Bachy, E., Le Gouill, S., Dreyling, M., Harigae, H., Bond, D., Andreadis, C., McSweeney, P., Kharfan-Dabaja, M., Newsome, S., Degtyarev, E., Awasthi, R., Del Corral, C., Andreola, G., Masood, A., Schuster, S.J., Jäger, U., Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386
(7): 629-639.
17 February 2022
Spectroelectrochemistry of cytochrome P450cam.
Bistolas, N., Christenson, A., Ruzgas, T., Jung, C., Scheller, F.W. and Wollenberger, U.
Biochemical and Biophysical Research Communications 314
(3): 810-816.
13 February 2004
A clonal expression biomarker associates with lung cancer mortality.
Biswas, D., Birkbak, N.J., Rosenthal, R., Hiley, C.T., Lim, E.L., Papp, K., Boeing, S., Krzystanek, M., Djureinovic, D., La Fleur, L., Greco, M., Döme, B., Fillinger, J., Brunnström, H., Wu, Y., Moore, D.A., Skrzypski, M., Abbosh, C., Litchfield, K., Al Bakir, M., Watkins, T.B.K., Veeriah, S., Wilson, G.A., Jamal-Hanjani, M., Moldvay, J., Botling, J., Chinnaiyan, A.M., Micke, P., Hackshaw, A., Bartek, J., Csabai, I., Szallasi, Z., Herrero, J., McGranahan, N. and Swanton, C.
Nature Medicine 25
(10): 1540-1548.
October 2019
Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.
Blackburn, J., Kawasaki, K., Porntaveetus, T., Kawasaki, M., Otsuka-Tanaka, Y., Miake, Y., Ota, M.S., Watanabe, M., Hishinuma, M., Nomoto, T., Oommen, S., Ghafoor, S., Harada, F., Nozawa-Inoue, K., Maeda, T., Peterkova, R., Lesot, H., Inoue, J., Akiyama, T., Schmidt-Ullrich, R., Liu, B., Hu, Y., Page, A., Ramirez, A., Sharpe, P.T. and Ohazama, A.
Journal of Dental Research 94
(1): 121-128.
January 2015
The role of Irf6 in tooth epithelial invagination.
Blackburn, J., Ohazama, A., Kawasaki, K., Otsuka-Tanaka, Y., Liu, B., Honda, K., Rountree, R.B., Hu, Y., Kawasaki, M., Birchmeier, W., Schmidt-Ullrich, R., Kinoshita, A., Schutte, B.C., Hammond, N.L., Dixon, M.J. and Sharpe, P.T.
Developmental Biology 365
(1): 61-70.
1 May 2012
Identification and ranking of recurrent neo-epitopes in cancer.
Blanc, E., Holtgrewe, M., Dhamodaran, A., Messerschmidt, C., Willimsky, G., Blankenstein, T. and Beule, D.
BMC Medical Genomics 12
: 171.
27 November 2019
High-throughput omics technologies: Potential tools for the investigation of influences of EMF on biological systems.
Blankenburg, M., Haberland, L., Elvers, H.D., Tannert, C. and Jandrig, B.
Current Genomics 10
(2): 86-92.
April 2009
Spontaneous and therapy-induced T cell responses to cancer.
Blankenstein, T.
Arzneimittelforschung 62
(1): S9.
November 2012
The determinants of tumour immunogenicity.
Blankenstein, T., Coulie, P.G., Gilboa, E. and Jaffee, E.M.
Nature Reviews Cancer 12
(4): 307-313.
April 2012
Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition.
Blattmann, C., Oertel, S., Ehemann, V., Thiemann, M., Huber, P.E., Bischof, M., Witt, O., Deubzer, H.E., Kulozik, A.E., Debus, J. and Weber, K.J.
International Journal of Radiation Oncology, Biology, Physics 78
(1): 237-245.
1 September 2010
The translocation motif of hepatitis B virus improves protein vaccination.
Bleifuss, E., Kammertoens, T., Hutloff, A., Quarcoo, D., Dorner, M., Straub, P., Uckert, W. and Hildt, E.
Cellular and Molecular Life Sciences 63
: 627-635.
March 2006
Systemic inflammation and normocytic anemia in DOCK11 deficiency.
Block, J., Rashkova, C., Castanon, I., Zoghi, S., Platon, J., Ardy, R.C., Fujiwara, M., Chaves, B., Schoppmeyer, R., van der Made, C.I., Jimenez Heredia, R., Harms, F.L., Alavi, S., Alsina, L., Sanchez Moreno, P., Ávila Polo, R., Cabrera-Pérez, R., Kostel Bal, S., Pfajfer, L., Ransmayr, B., Mautner, A.K., Kondo, R., Tinnacher, A., Caldera, M., Schuster, M., Domínguez Conde, C., Platzer, R., Salzer, E., Boyer, T., Brunner, H.G., Nooitgedagt-Frons, J.E., Iglesias, E., Deyà-Martinez, A., Camacho-Lovillo, M., Menche, J., Bock, C., Huppa, J.B., Pickl, W.F., Distel, M., Yoder, J.A., Traver, D., Engelhardt, K.R., Linden, T., Kager, L., Hannich, J.T., Hoischen, A., Hambleton, S., Illsinger, S., Da Costa, L., Kutsche, K., Chavoshzadeh, Z., van Buul, J.D., Antón, J., Calzada-Hernández, J., Neth, O., Viaud, J., Nishikimi, A., Dupré, L. and Boztug, K.
New England Journal of Medicine 389
(6): 527-539.
10 August 2023
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Bloehdorn, J., Braun, A., Taylor-Weiner, A., Jebaraj, B.M.C., Robrecht, S., Krzykalla, J., Pan, H., Giza, A., Akylzhanova, G., Holzmann, K., Scheffold, A., Johnston, H.E., Yeh, R.F., Klymenko, T., Tausch, E., Eichhorst, B., Bullinger, L., Fischer, K., Weisser, M., Robak, T., Schneider, C., Gribben, J., Dahal, L.N., Carter, M.J., Elemento, O., Landau, D.A., Neuberg, D.S., Cragg, M.S., Benner, A., Hallek, M., Wu, C.J., Döhner, H., Stilgenbauer, S. and Mertens, D.
Nature Communications 12
(1): 5395.
13 September 2021
CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J., Kieback, E., Marino, S.F., Oden, F., Westermann, J., Chmielewski, M., Abken, H., Uckert, W., Höpken, U.E. and Rehm, A.
Molecular Therapy 26
(8): 1906-1920.
1 August 2018
Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T., Funck, K., Wollweber, F., Lisicki, E., von der Malsburg, K., von der Malsburg, A., Laborenz, J., Noel, J.K., Hessenberger, M., Jungbluth, S., Bernert, C., Kunz, S., Riedel, D., Lilie, H., Jakobs, S., van der Laan, M. and Daumke, O.
Science Advances 8
(35): eabo4946.
2 September 2022
Microsatellite instability analysis: a multicenter study for reliability and quality control.
Bocker, T., Diermann, J., Friedl, W., Gebert, J., Holinski-Feder, E., Karner-Hanusch, J., von Knebel-Doeberitz, M., Koelble, K., Moeslein, G., Schackert, H.K., Witz, H.C., Fishel, R. and Rueschoff, J.
Cancer Research 57
(21): 4739-4743.
1 November 1997
SLM2 is a novel cardiac splicing factor involved in heart failure due to dilated cardiomyopathy.
Boeckel, J.N., Möbius-Winkler, M., Müller, M., Rebs, S., Eger, N., Schoppe, L., Tappu, R., Kokot, K.E., Kneuer, J.M., Gaul, S., Bordalo, D.M., Lai, A., Haas, J., Ghanbari, M., Drewe-Boss, P., Liss, M., Katus, H.A., Ohler, U., Gotthardt, M., Laufs, U., Streckfuss-Bömeke, K. and Meder, B.
Genomics Proteomics & Bioinformatics 20
(1): 129-146.
February 2022
Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N., Perret, M.F., Glaser, S.F., Seeger, T., Heumüller, A.W., Chen, W., John, D., Kokot, K.E., Katus, H.A., Haas, J., Lackner, M.K., Kayvanpour, E., Grabe, N., Dieterich, C., von Haehling, S., Ebner, N., Hünecke, S., Leuschner, F., Fichtlscherer, S., Meder, B., Zeiher, A.M., Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126
: 13-22.
January 2019
The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A., Babila, J.T., Wiglenda, T., Diez, L., Jacob, M., Nietfeld, W., Huska, M.R., Haenig, C., Groenke, N., Buntru, A., Blanc, E., Meier, J.C., Vannoni, E., Erck, C., Friedrich, B., Martens, H., Neuendorf, N., Schnoegl, S., Wolfer, D.P., Loos, M., Beule, D., Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26
(1): 109-120.
17 January 2019
A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y., Malehmir, M., Healy, M.E., Bettermann, K., Lorentzen, A., Vucur, M., Ahuja, A.K., Böhm, F., Mertens, J.C., Shimizu, Y., Frick, L., Remouchamps, C., Mutreja, K., Kähne, T., Sundaravinayagam, D., Wolf, M.J., Rehrauer, H., Koppe, C., Speicher, T., Padrissa-Altés, S., Maire, R., Schattenberg, J.M., Jeong, J.S., Liu, Lei, Zwirner, S., Boger, R., Hüser, N., Davis, R.J., Müllhaupt, B., Moch, H., Schulze-Bergkamen, H., Clavien, P.A., Werner, S., Borsig, L., Luther, S.A., Jost, P.J., Weinlich, R., Unger, K., Behrens, A., Hillert, L., Dillon, C., Di Virgilio, M., Wallach, D., Dejardin, E., Zender, L., Naumann, M., Walczak, H., Green, D.R., Lopes, M., Lavrik, I., Luedde, T., Heikenwalder, M. and Weber, A.
Cancer Cell 32
(3): 342-359.
11 September 2017
Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme.
Boehm, K., Herter, T., Mueller, J.J., Borriss, R. and Heinemann, U.
FEBS Journal 277
(5): 1284-1296.
March 2010
Dendritic cell progenitor is transformed by a conditional v-rel estrogen receptor fusion v-relER.
Boehmelt, G., Madruga, J., Doerfler, P., Briegel, K., Schwarz, H., Enrietto, P. and Zenke, M.
Cell 80
(2): 341-352.
27 January 1995
Hormone-regulated v-rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression.
Boehmelt, G., Walker, A., Kabrun, N., Mellitzer, G., Beug, H., Zenke, M. and Enrietto, P.J.
EMBO Journal 11
(12): 4641-4652.
December 1992
Visceral leishmaniasis diagnosis and reporting delays as an obstacle to timely response actions in Nepal and India.
Boettcher, J.P., Siwakoti, Y., Milojkovic, A., Siddiqui, N.A., Gurung, C.K., Rijal, S., Das, P., Kroeger, A. and Banjara, M.R.
BMC Infectious Diseases 15
(1): 43.
6 February 2015
Combining metabolic pulse labeling and quantitative proteomics to monitor protein synthesis upon viral infection.
Bogdanow, B., Katsimani, N., Liu, F. and Selbach, M.
Methods in Molecular Biology 2610
: 149-165.
2023
Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis.
Bogdanow, B., Schmidt, M., Weisbach, H., Gruska, I., Vetter, B., Imami, K., Ostermann, E., Brune, W., Selbach, M., Hagemeier, C. and Wiebusch, L.
Nature Communications 11
(1): 4845.
24 September 2020
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B., Wang, X., Eichelbaum, K., Sadewasser, A., Husic, I., Paki, K., Budt, M., Hergeselle, M., Vetter, B., Hou, J., Chen, W., Wiebusch, L., Meyer, I.M., Wolff, T. and Selbach, M.
Nature Communications 10
(1): 5518.
4 December 2019
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska, R., Mikecin, A.M., Kaschutnig, P., Fawaz, M., Büchler-Schäff, M., Le, D., Ganuza, M., Vollmer, A., Paffenholz, S.V., Asada, N., Rodriguez-Correa, E., Frauhammer, F., Buettner, F., Ball, M., Knoch, J., Stäble, S., Walter, D., Petri, A., Carreño-Gonzalez, M.J., Wagner, V., Brors, B., Haas, S., Lipka, D.B., Essers, M.A.G., Weru, V., Holland-Letz, T., Mallm, J.P., Rippe, K., Krämer, S., Schlesner, M., McKinney Freeman, S., Florian, M.C., King, K.Y., Frenette, P.S., Rieger, M.A. and Milsom, M.D.
Cell Stem Cell 29
(8): 1273-1284.
4 August 2022
New targeted agents in acute myeloid leukemia: new hope on the rise.
Bohl, S.R., Bullinger, L. and Rücker, F.G.
International Journal of Molecular Sciences 20
(8)
23 April 2019
Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma.
Bohl, S.R., Schmalbrock, L.K., Bauhuf, I., Meyer, T., Dolnik, A., Szyska, M., Blätte, T.J., Knödler, S., Röhner, L., Miller, D., Kull, M., Langer, C., Döhner, H., Letai, A., Damm, F., Heckl, D., Bullinger, L. and Krönke, J.
Blood Advances 5
(9): 2391-2402.
11 May 2021
Cytolysis of leukemic B-cells by T-cells activated via 2 bispecific antibodies.
Bohlen, H., Manzke, O., Patel, B., Moldenhauer, G., Doerken, B., von Fliedner, V., Diehl, V. and Tesch, H.
Cancer Research 53
(18): 4310-4314.
15 September 1993
Treatment of brain metastases in patients with testicular cancer.
Bokemeyer, C., Nowak, P., Haupt, A., Metzner, B., Koehne, H., Hartmann, J.T., Kanz, L. and Schmoll, H.J.
Journal of Clinical Oncology 15
(4): 1449-1454.
April 1997
Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N., Bader, M., Willnow, T.E., Wiedenmann, B. and Sigal, M.
Frontiers in Endocrinology 15
: 1331231.
17 April 2024
CAFE: an R package for the detection of gross chromosomal abnormalities from gene expression microarray data.
Bollen, S., Leddin, M., Andrade-Navarro, M.A. and Mah, N.
Bioinformatics 30
(10): 1484-1485.
15 May 2014
Prognoserelevanz von biologischen und molekularen Markern in der Onkologie : Kriterien fur Studienplanung und -Interpretation. [Prognostic relevance of biological and molecular markers in oncology. Criteria for planning and interpreting studies].
Bollschweiler, E., Schneider, P.M., Moenig, S.P., Altendorf-Hofmann, A., Mansmann, U., Lehmacher, W., Schlag, P.M., Merkel, S., Hohenberger, W., Izbicki, J.R., Hermanek, P. and Hoelscher, A.H.
Chirurg 74
(2): 139-144.
February 2003
VISOR: a versatile haplotype-aware structural variant simulator for short- and long-read sequencing.
Bolognini, D., Sanders, A., Korbel, J.O., Magi, A., Benes, V. and Rausch, T.
Bioinformatics 36
(4): 1267-1269.
15 February 2020
ICOS+Th cells produce distinct cytokines in different mucosal immune responses.
Bonhagen, K., Liesenfeld, O., Stadecker, M.J., Hutloff, A., Erb, K., Coyle, A.J., Lipp, M., Kroczek, R.A. and Kamradt, T.
European Journal of Immunology 33
(2): 392-401.
February 2003
Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors.
Bonifacius, A., Lamottke, B., Tischer-Zimmermann, S., Schultze-Florey, R., Goudeva, L., Heuft, H.G., Arseniev, L., Beier, R., Beutel, G., Cario, G., Fröhlich, B., Greil, J., Hansmann, L., Hasenkamp, J., Höfs, M., Hundsdoerfer, P., Jost, E., Kafa, K., Kriege, O., Kröger, N., Mathas, S., Meisel, R., Nathrath, M., Putkonen, M., Ravens, S., Reinhardt, H.C., Sala, E., Sauer, M.G, Schmitt, C., Schroers, R., Steckel, N.K., Trappe, R.U., Verbeek, M., Wolff, D., Blasczyk, R., Eiz-Vesper, B. and Maecker-Kolhoff, B.
Journal of Clinical Investigation 133
(12): e163548.
15 June 2023
Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy.
Boogerd, C.J., Lacraz, G.P.A., Vértesy, Á., van Kampen, S.J., Perini, I., de Ruiter, H., Versteeg, D., Brodehl, A., van der Kraak, P., Giacca, M., de Jonge, N., Junker, J.P., van Oudenaarden, A., Vink, A. and van Rooij, E.
Cardiovascular Research 119
(2): 477-491.
February 2023
Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial.
Borchmann, P., Ferdinandus, J., Schneider, G., Moccia, A., Greil, R., Hertzberg, M., Schaub, V., Hüttmann, A., Keil, F., Dierlamm, J., Hänel, M., Novak, U., Meissner, J., Zimmermann, A., Mathas, S., Zijlstra, J.M., Fosså, A., Viardot, A., Hertenstein, B., Martin, S., Giri, P., Scholl, S., Topp, M.S., Jung, W., Vucinic, V., Beck, H.J., Kerkhoff, A., Unger, B., Rank, A., Schroers, R., zum Büschenfelde, C.M., de Wit, M., Trautmann-Grill, K., Kamper, P., Molin, D., Kreissl, S., Kaul, H., von Tresckow, B., Borchmann, S., Behringer, K., Fuchs, M., Rosenwald, A., Klapper, W., Eich, H.T., Baues, C., Zomas, A., Hallek, M., Dietlein, M., Kobe, C. and Diehl, V.
Lancet 404
(10450): 341-352.
27 July 2024
Eight cycles of escalated-dose BEACOPP compared with four cycles of escalated-dose BEACOPP followed by four cycles of baseline-dose BEACOPP with or without radiotherapy in patients with advanced-stage Hodgkin's lymphoma: final analysis of the HD12 trial of the German Hodgkin study group.
Borchmann, P., Haverkamp, H., Diehl, V., Cerny, T., Markova, J., Ho, A.D., Eich, H.T., Mueller-Hermelink, H.K., Kanz, L., Greil, R., Rank, A., Paulus, U., Smardova, L., Huber, C., Doerken, B., Nerl, C., Krause, S.W., Mueller, R.P., Fuchs, M. and Engert, A.
Journal of Clinical Oncology 29
(32): 4234-4342.
10 November 2011
PET-guided omission of radiotherapy in early-stage unfavourable Hodgkin lymphoma (GHSG HD17): a multicentre, open-label, randomised, phase 3 trial.
Borchmann, P., Plütschow, A., Kobe, C., Greil, R., Meissner, J., Topp, M.S., Ostermann, H., Dierlamm, J., Mohm, J., Thiemer, J., Sökler, M., Kerkhoff, A., Ahlborn, M., Halbsguth, T.V., Martin, S., Keller, U., Balabanov, S., Pabst, T., Vogelhuber, M., Hüttmann, A., Wilhelm, M., Zijlstra, J.M., Moccia, A., Kuhnert, G., Bröckelmann, P.J., von Tresckow, B., Fuchs, M., Klimm, B., Rosenwald, A., Eich, H., Baues, C., Marnitz, S., Hallek, M., Diehl, V., Dietlein, M. and Engert, A.
Lancet Oncology 22
(2): 223-234.
February 2021
WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N., Gloaguen, Y., Opialla, T., Blanc, E., Sicard, E., Royer, A.L., Le Bizec, B., Durand, S., Migné, C., Pétéra, M., Pujos-Guillot, E., Giacomoni, F., Guitton, Y., Beule, D. and Kirwan, J.
Metabolites 9
(9): 171.
21 August 2019
Mitochondrial membrane potential is dependent on the oligomeric state of F1F0-ATP synthase supracomplexes.
Bornhoevd, C., Vogel, F., Neupert, W. and Reichert, A.S.
Journal of Biological Chemistry 281
(20): 13990-13998.
19 May 2006
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G., Kleinewietfeld, M., Di Mitri, D., Sternjak, A., Diamantini, A., Giometto, R., Hoepner, S., Centonze, D., Bernardi, G., Dell'Acqua, M.L., Rossini, P.M., Battistini, L., Roetzschke, O. and Falk, K.
Blood 110
(4): 1225-1232.
15 August 2007
Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Bothmer, A., Robbiani, D.F., Di Virgilio, M., Bunting, S.F., Klein, I.A., Feldhahn, N., Barlow, J., Chen, H.T., Bosque, D., Callen, E., Nussenzweig, A. and Nussenzweig, M.C.
Molecular Cell 42
(3): 319-329.
6 May 2011
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.
Bouchard, C., Lee, S., Paulus-Hock, V., Loddenkemper, C., Eilers, M. and Schmitt, C.A.
Genes & Development 21
(21): 2775-2787.
1 November 2007
Single-cell time series analysis reveals the dynamics of HSPC response to inflammation.
Bouman, B.J., Demerdash, Y., Sood, S., Grünschläger, F., Pilz, F., Itani, A.R., Kuck, A., Marot-Lassauzaie, V., Haas, S., Haghverdi, L. and Essers, M.A.
Life Science Alliance 7
(3): e202302309.
March 2024
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Bowl, M.R., Simon, M.M., Ingham, N.J., Greenaway, S., Santos, L., Cater, H., Taylor, S., Mason, J., Kurbatova, N., Pearson, S., Bower, L.R., Clary, D.A., Meziane, H., Reilly, P., Minowa, O., Kelsey, L., Tocchini-Valentini, G.P., Gao, X., Bradley, A., Skarnes, W.C., Moore, M., Beaudet, A.L., Justice, M.J., Seavitt, J., Dickinson, M.E., Wurst, W., Hrabe de Angelis, M., Herault, Y., Wakana, S., Nutter, L.M.J., Flenniken, A.M., McKerlie, C., Murray, S.A., Svenson, K.L., Braun, R.E., West, D.B., Lloyd, K.C.K., Adams, D.J., White, J., Karp, N., Flicek, P., Smedley, D., Meehan, T.F., Parkinson, H.E., Teboul, L.M., Wells, S., Steel, K.P., Mallon, A.M. and Brown, S.D.M.
Nature Communications 8
(1): 886.
12 October 2017
Neurogenic amplification of immune complex inflammation.
Bozic, C.R., Lu, B., Höpken, U.E., Gerard, C. and Gerard, N.P.
Science 273
(5282): 1722-1725.
20 September 1996
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Bracken, A.P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Moench, K., Minucci, S., Porse, B.T., Marine, J.-C., Hansen, K.H. and Helin, K.
Genes & Development 21
(5): 525-530.
1 March 2007
Efficacy of MS-275, a selective inhibitor of class I histone deacetylases, in human colon cancer models.
Bracker, T.U., Sommer, A., Fichtner, I., Faus, H., Haendler, B. and Hess-Stumpp, H.
International Journal of Oncology 35
(4): 909-920.
October 2009
A high-resolution root spatiotemporal map reveals dominant expression patterns.
Brady, S.M., Orlando, D.A., Lee, J.Y., Wang, J.Y., Koch, J., Dinneny, J.R., Mace, D., Ohler, U. and Benfey, P.N.
Science 318
(5851): 801-806.
2 November 2007
A stele-enriched gene regulatory network in the Arabidopsis root.
Brady, S.M., Zhang, L., Megraw, M., Martinez, N.J., Jiang, E., Yi, C.S., Liu, W., Zeng, A., Taylor-Teeples, M., Kim, D., Ahnert, S., Ohler, U., Ware, D., Walhout, A.J.M. and Benfey, P.N.
Molecular Systems Biology 7
: 459.
18 January 2011
Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M., Lee, S., Loddenkemper, C., Rudolph, C., Peters, A.H., Schlegelberger, B., Stein, H., Doerken, B., Jenuwein, T. and Schmitt, C.A.
Nature 436
(7051): 660-665.
4 August 2005
Conditioning with fludarabine and treosulfan compared to FLAMSA-RIC in allogeneic stem cell transplantation for myeloid malignancies: a retrospective single-center analysis.
Braitsch, K., Schwarz, A., Koch, K., Hubbuch, M., Menzel, H., Keller, U., Götze, K.S., Bassermann, F., Herhaus, P. and Verbeek, M.
Annals of Hematology 101
(6): 1311-1319.
June 2022
Monomeric TCRs drive T cell antigen recognition.
Brameshuber, M., Kellner, F., Rossboth, B.K., Ta, H., Alge, K., Sevcsik, E., Göhring, J., Axmann, M., Baumgart, F., Gascoigne, N.R.J., Davis, S.J., Stockinger, H., Schütz, G.J. and Huppa, J.B.
Nature Immunology 19
(5): 487-496.
May 2018
A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand, J., Smith, E.S.J., Schwefel, D., Lapatsina, L., Poole, K., Omerbasic, D., Kozlenkov, A., Behlke, J., Lewin, G.R. and Daumke, O.
EMBO Journal 31
(17): 3635-3646.
29 August 2012
Impact of a specialised palliative care intervention in patients with advanced soft tissue sarcoma - a single-centre retrospective analysis.
Brandes, F., Striefler, J.K., Dörr, A., Schmiester, M., Märdian, S., Koulaxouzidis, G., Kaul, D., Behzadi, A., Thuss-Patience, P., Ahn, J., Pelzer, U., Bullinger, L. and Flörcken, A.
BMC Palliative Care 20
(1): 16.
14 January 2021
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
Brandl, C., Ortiz, O., Röttig, B., Wefers, B., Wurst, W. and Kühn, R.
FEBS Open Bio 5
: 26-35.
2015
Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.
Braten, O., Livneh, I., Ziv, T., Admon, A., Kehat, I., Caspi, L.H., Gonen, H., Bercovich, B., Godzik, A., Jahandideh, S., Jaroszewski, L., Sommer, T., Kwon, Y.T., Guharoy, M., Tompa, P. and Ciechanover, A.
Proceedings of the National Academy of Sciences of the United States of America 113
(32): E4639-E4647.
9 August 2016
Relapse of NPM1-mutated AML with extramedullary manifestation 17 years after allogeneic hematopoietic stem cell transplantation.
Braune, J., Rieger, K., Blau, O., Keller, U., Bullinger, L. and Krönke, J.
Case Reports in Hematology 2022
: 3317936.
28 December 2022
TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck, F., Fischer, B., Witt, M., Muschhammer, J., Oelrich, J., da Costa Avelar, P.H., Tsoka, S., Bullinger, L., Seubert, E., Smit, D.J., Bokemeyer, C., Ackermann, C., Wellbrock, J., Haag, F. and Fiedler, W.
Journal for ImmunoTherapy of Cancer 10
(12): e004794.
22 December 2022
High-resolution experimental and computational profiling of tissue-specific known and novel miRNAs in Arabidopsis.
Breakfield, N.W., Corcoran, D.L., Petricka, J.J., Shen, J., Sae-Seaw, J., Rubio-Somoza, I., Weigel, D., Ohler, U. and Benfey, P.N.
Genome Research 22
(1): 163-176.
January 2012
Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.
Breit, T.M., Mol, E.J., Wolvers-Tettero, I.L., Ludwig, W.D., van Wering, E.R. and van Dongen, J.J.
Journal of Experimental Medicine 177
(4): 965-977.
1 April 1993
Optimization of synthetic molecular reporters for a mesenchymal glioblastoma transcriptional program by integer programming.
Breitenbach, T., Schmitt, M.J. and Dandekar, T.
Bioinformatics 38
(17): 4162-4171.
1 September 2022
Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production.
Breitfeld, D., Ohl, L., Kremmer, E., Ellwart, J., Sallusto, F., Lipp, M. and Foerster, R.
Journal of Experimental Medicine 192
(11): 1545-1551.
4 December 2000
M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
Breitkreuz-Korff, O., Tscheik, C., Del Vecchio, G., Dithmer, S., Walther, W., Orthmann, A., Wolburg, H., Haseloff, R.F., Schröder, L., Blasig, I.E. and Winkler, L.
Journal of Controlled Release 330
: 137-148.
10 August 2021
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Brembeck, F.H., Schwarz-Romond, T., Bakkers, J., Wilhelm, S., Hammerschmidt, M. and Birchmeier, W.
Genes & Development 18
(18): 2225-2230.
15 September 2004
BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H., Wiese, M., Zatula, N., Grigoryan, T., Dai, Y., Fritzmann, J. and Birchmeier, W.
Gastroenterology 141
(4): 1359-1370.
October 2011
A rapid bioinformatic method identifies novel genes with direct clinical relevance to colon cancer.
Brett, D., Kemmner, W., Koch, G., Roefzaad, C., Gross, S. and Schlag, P.M.
Oncogene 20
(33): 4581-4585.
27 July 2001
Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness.
Breun, M., Flock, K., Feldheim, J., Nattmann, A., Monoranu, C.M., Herrmann, P., Ernestus, R.I., Löhr, M., Hagemann, C. and Stein, U.
Cancers 15
(16): 4089.
14 August 2023
Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates.
Briesemeister, D., Friese, C., Isern, C.C., Dietz, E., Blankenstein, T., Thoene-Reineke, C. and Kammertoens, T.
Cytokine 60
(3): 626-633.
December 2012
Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis.
Briesemeister, D., Sommermeyer, D., Loddenkemper, C., Loew, R., Uckert, W., Blankenstein, T. and Kammertoens, T.
International Journal of Cancer 128
(2): 371-378.
15 January 2011
Mechanisms of targeting the MDM2-p53-FOXM1 axis in well-differentiated intestinal neuroendocrine tumors.
Briest, F., Grass, I., Sedding, D., Moebs, M., Christen, F., Benecke, J., Fuchs, K., Mende, S., Kaemmerer, D., Saenger, J., Kunze, A., Geisler, C., Freitag, H., Lewens, F., Worpenberg, L., Iwaszkiewicz, S., Siegmund, B., Walther, W., Hummel, M. and Grabowski, P.
Neuroendocrinology 107
(1): 1-23.
July 2018
Does the proteasome inhibitor bortezomib sensitize to DNA-damaging therapy in gastroenteropancreatic neuroendocrine neoplasms? - A preclinical assessment in vitro and in vivo.
Briest, F., Koziolek, E.J., Albrecht, J., Schmidt, F., Bernsen, M.R., Haeck, J., Kühl, A.A., Sedding, D., Hartung, T., Exner, S., Welzel, M., Fischer, C., Grötzinger, C., Brenner, W., Baum, R.P. and Grabowski, P.
Neoplasia 23
(1): 80-98.
January 2021
Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F., Noerenberg, D., Hennch, C., Yoshida, K., Hablesreiter, R., Nimo, J., Sasca, D., Kirchner, M., Mansouri, L., Inoue, Y., Wiegand, L., Staiger, A.M., Casadei, B., Korkolopoulou, P., Weiner, J., Lopez-Guillermo, A., Warth, A., Schneider, T., Nagy, Á., Klapper, W., Hummel, M., Kanellis, G., Anagnostopoulos, I., Mertins, P., Bullinger, L., Rosenquist, R., Vassilakopoulos, T.P., Ott, G., Ogawa, S. and Damm, F.
Leukemia 37
(11): 2237-2249.
November 2023
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.
Brinkmann, V., Foroutan, H., Sachs, M., Weidner, K.M. and Birchmeier, W.
Journal of Cell Biology 131
(6 Pt. 1): 1573-1586.
December 1995
Rap-specific GTPase activating protein follows an alternative mechanism.
Brinkmann, T., Daumke, O., Herbrand, U., Kühlmann, D., Stege, P., Ahmadian, M.R. and Wittinghofer, A.
Journal of Biological Chemistry 277
(15): 12525-31.
12 April 2002
NF-κB determines Paneth versus goblet cell fate decision in the small intestine.
Brischetto, C., Krieger, K., Klotz, C., Krahn, I., Kunz, S., Kolesnichenko, M., Mucka, P., Heuberger, J., Scheidereit, C. and Schmidt-Ullrich, R.
Development 148
(21): dev199683.
November 2021
MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors.
Brischwein, K., Schlereth, B., Guller, B., Steiger, C., Wolf, A., Lutterbuese, R., Offner, S., Locher, M., Urbig, T., Raum, T., Kleindienst, P., Wimberger, P., Kimmig, R., Fichtner, I., Kufer, P., Hofmeister, R., da Silva, A.J. and Baeuerle, P.A.
Molecular Immunology 43
(8): 1129-1143.
March 2006
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.
Brockmann, M., Poon, E., Berry, T., Carstensen, A., Deubzer, H.E., Rycak, L., Jamin, Y., Thway, K., Robinson, S.P., Roels, F., Witt, O., Fischer, M., Chesler, L. and Eilers, M.
Cancer Cell 24
(1): 75-89.
8 July 2013
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.
Brocks, D., Schmidt, C.R., Daskalakis, M., Jang, H.S., Shah, N.M., Li, D., Li, J., Zhang, B., Hou, Y., Laudato, S., Lipka, D.B., Schott, J., Bierhoff, H., Assenov, Y., Helf, M., Ressnerova, A., Islam, M.S., Lindroth, A.M., Haas, S., Essers, M., Imbusch, C.D., Brors, B., Oehme, I., Witt, O., Lübbert, M., Mallm, J.P., Rippe, K., Will, R., Weichenhan, D., Stoecklin, G., Gerhäuser, C., Oakes, C.C., Wang, T. and Plass, C.
Nature Genetics 49
(7): 1052-1060.
July 2017
Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line - cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.
Brockstedt, E., Rickers, A., Kostka, S., Laubersheimer, A., Doerken, B., Wittmann-Liebold, B., Bommert, K. and Otto, A.
Journal of Biological Chemistry 273
(43): 28057-28064.
23 October 1998
Single amino acid exchange in bacteriophage HK620 tailspike protein results in thousand-fold increase of its oligosaccharide affinity.
Broeker, N.K., Gohlke, U., Müller, J.J., Uetrecht, C., Heinemann, U., Seckler, R. and Barbirz, S.
Glycobiology 23
(1): 59-68.
January 2013
Time-resolved DNA release from an O-antigen specific Salmonella bacteriophage with a contractile tail.
Broeker, N.K., Roske, Y., Valleriani, A., Stephan, M.S., Andres, D., Koetz, J., Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 294
(31): 11751-11761.
2 August 2019
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, A.M., Vockentanz, L., Kharazi, S., Huska, M.R., Mancini, E., Scheller, M., Kuhl, C., Enns, A., Prinz, M., Jaenisch, R., Nerlov, C., Leutz, A., Andrade-Navarro, M.A., Jacobsen, S.E. and Rosenbauer, F.
Nature Genetics 41
(11): 1207-1215.
November 2009
Stat3 activation is required for cellular transformation by v-src.
Bromberg, J.F., Horvath, C.M., Besser, D., Lathem, W.W. and Darnell, J.E.
Molecular and Cellular Biology 18
(5): 2553-2558.
May 1998
Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy.
Brueckner, B., Rius, M., Rivera Markelova, M., Fichtner, I., Hals, P.A., Sandvold, M.L. and Lyko, F.
Molecular Cancer Therapeutics 9
(5): 1256-1264.
May 2010
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.
Bruedigam, C., Bagger, F.O., Heidel, F.H., Paine Kuhn, C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W.
Cell Stem Cell 15
(6): 775-90.
4 December 2014
Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia.
Bruedigam, C., Porter, A.H., Song, A., Vroeg In de Wei, G., Stoll, T., Straube, J., Cooper, L., Cheng, G., Kahl, V.F.S., Sobinoff, A.P., Ling, V.Y., Jebaraj, B.M.C., Janardhanan, Y., Haldar, R., Bray, L.J., Bullinger, L., Heidel, F.H., Kennedy, G.A., Hill, M.M., Pickett, H.A., Abdel-Wahab, O., Hartel, G. and Lane, S.W.
Nature Cancer 5
(1): 47-65.
January 2024
Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation.
Brunner, A.D., Thielert, M., Vasilopoulou, C., Ammar, C., Coscia, F., Mund, A., Hoerning, O.B., Bache, N., Apalategui, A., Lubeck, M., Richter, S., Fischer, D.S., Raether, O., Park, M.A., Meier, F., Theis, F.J. and Mann, M.
Molecular Systems Biology 18
(3): e10798.
1 March 2022
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses.
Brunner, T.M., Serve, S., Marx, A.F., Fadejeva, J., Saikali, P., Dzamukova, M., Durán-Hernández, N., Kommer, C., Heinrich, F., Durek, P., Heinz, G.A., Höfer, T., Mashreghi, M.F., Kühn, R., Pinschewer, D.D. and Löhning, M.
Nature Immunology 25
(2): 256-267.
February 2024
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann, J., Lorenz, C., Borchmann, S., Nishii, K., Wegner, J., Meder, L., Ostendorp, J., Ast, D.F., Heimsoeth, A., Nakasuka, T., Hirabae, A., Okawa, S., Dammert, M.A., Plenker, D., Klein, S., Lohneis, P., Gu, J., Godfrey, L.K., Forster, J., Trajkovic-Arsic, M., Zillinger, T., Haarmann, M., Quaas, A., Lennartz, S., Schmiel, M., D'Rozario, J., Thomas, E.S., Li, H., Schmitt, C.A., George, J., Thomas, R.K., von Karstedt, S., Hartmann, G., Büttner, R., Ullrich, R.T., Siveke, J.T., Ohashi, K., Schlee, M. and Sos, M.L.
Nature Communications 12
(1): 5505.
17 September 2021
Nivolumab and doxorubicin, vinblastine, and dacarbazine in early-stage unfavorable Hodgkin Lymphoma: final analysis of the randomized german Hodgkin study group phase II NIVAHL trial.
Bröckelmann, P.J., Bühnen, I., Meissner, J., Trautmann-Grill, K., Herhaus, P., Halbsguth, T.V., Schaub, V., Kerkhoff, A., Mathas, S., Bormann, M., Dickhut, A., Kaul, H., Fuchs, M., Kobe, C., Baues, C., Borchmann, P., Engert, A. and von Tresckow, B.
Journal of Clinical Oncology 41
(6): 1193-1199.
20 February 2023
Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial.
Bröckelmann, P.J., Goergen, H., Keller, U., Meissner, J., Ordemann, R., Halbsguth, T.V., Sasse, S., Sökler, M., Kerkhoff, A., Mathas, S., Hüttmann, A., Bormann, M., Zimmermann, A., Mettler, J., Fuchs, M., von Tresckow, B., Baues, C., Rosenwald, A., Klapper, W., Kobe, C., Borchmann, P. and Engert, A.
JAMA Oncology 6
(6): 872-880.
June 2020
Phase I trial of an allogeneic gene-modified tumor cell vaccine (RCC-26/CD80/IL-2) in patients with metastatic renal cell carcinoma.
Buchner, A., Pohla, H., Willimsky, G., Frankenberger, B., Frank, R., Baur-Melnyk, A., Siebels, M., Stief, C.G., Hofstetter, A., Kopp, J., Pezzutto, A., Blankenstein, T., Oberneder, R. and Schendel, D.J.
Human Gene Therapy 21
(3): 285-297.
March 2010
Systematic identification of A-to-I RNA editing in zebrafish development and adult organs.
Buchumenski, I., Holler, K., Appelbaum, L., Eisenberg, E., Junker, J.P. and Levanon, E.Y.
Nucleic Acids Research 49
(8): 4325-4337.
7 May 2021
6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group.
Buechner, T., Hiddemann, W., Berdel, W.E., Woermann, B., Schoch, C., Fonatsch, C., Loeffler, H., Haferlach, T., Ludwig, W.D., Maschmeyer, G., Staib, P., Aul, C., Grueneisen, A., Lengfelder, E., Frickhofen, N., Kern, W., Serve, H.L., Mesters, R.M., Sauerland, M.C. and Heinecke, A.
Journal of Clinical Oncology 21
: 4496-4504.
15 December 2003
The receptor tyrosine kinase p185HER2 is expressed on a subset of B-lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia.
Buehring, H.J., Sures, I., Jallal, B., Weiss, F.U., Busch, F.W., Ludwig, W.D., Handgretinger, R., Waller, H.D. and Ullrich, A.
Blood 86
(5): 1916-1923.
1 September 1995
Structural evidence of active site adaptability towards different sized substrates of aromatic amino acid aminotransferase from Psychrobacter sp. B6.
Bujacz, A., Rum, J., Rutkiewicz, M., Pietrzyk-Brzezinska, A.J. and Bujacz, G.
Materials 14
(12): 3351.
2 June 2021
PRAME-induced inhibition of retinoic acid receptor signaling-mediated differentiation - a possible target for ATRA response in AML without t(15;17).
Bullinger, L., Schlenk, R.F., Götz, M., Botzenhardt, U., Hofmann, S., Russ, A.C., Babiak, A., Zhang, L., Schneider, V., Döhner, K., Schmitt, M., Döhner, H. and Greiner, J.
Clinical Cancer Research 19
(9): 2562-71.
1 May 2013
RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer.
Bunse, M., Bendle, G.M., Linnemann, C., Bies, L., Schulz, S., Schumacher, T.N. and Uckert, W.
Molecular Therapy 22
(11): 1983-1991.
November 2014
Generation of redirected engineered human chimeric antigen receptor (CAR) T cells.
Bunse, M. and Höpken, U.E.
Methods in Molecular Biology 2521
(3): 67-83.
23 June 2022
CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells.
Bunse, M., Pfeilschifter, J., Bluhm, J., Zschummel, M., Joedicke, J.J., Wirges, A., Stark, H., Kretschmer, V., Chmielewski, M., Uckert, W., Abken, H., Westermann, J., Rehm, A. and Höpken, U.E.
Nature Communications 12
(1): 240.
11 January 2021
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Buonamici, S., Trimarchi, T., Ruocco, M.G., Reavie, L., Cathelin, S., Mar, B.G., Klinakis, A., Lukyanov, Y., Tseng, J.C., Sen, F., Gehrie, E., Li, M., Newcomb, E., Zavadil, J., Meruelo, D., Lipp, M., Ibrahim, S., Efstratiadis, A., Zagzag, D., Bromberg, J.S., Dustin, M.L. and Aifantis, I.
Nature 459
(7249): 1000-1004.
18 June 2009
Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Buonocore, F., Kuehnen, P., Suntharalingham, J.P., Del Valle, I., Digweed, M., Stachelscheid, H., Khajavi, N., Didi, M., Brady, A.F., Blankenstein, O., Procter, A.M., Dimitri, P., Wales, J.K.H., Ghirri, P., Knoebl, D., Strahm, B., Erlacher, M., Wlodarski, M.W., Chen, W., Kokai, G.K., Anderson, G., Morrogh, D., Moulding, D.A., McKee, S. A., Niemeyer, C.M., Grueters, A. and Achermann, J.C.
Journal of Clinical Investigation 127
(5): 1700-1713.
1 May 2017
Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.
Burek, M., Maddika, S., Burek, C.J., Daniel, P.T., Schulze-Osthoff, K. and Los, M.
Oncogene 25
: 2213-2222.
6 April 2006
Copy-number dosage regulates telomere maintenance and disease-associated pathways in neuroblastoma.
Burkert, M., Blanc, E., Thiessen, N., Weber, C., Toedling, J., Monti, R., Dombrowe, V.M., de Biase, M.S., Kaufmann, T.L., Haase, K., Waszak, S.M., Eggert, A., Beule, D., Schulte, J.H., Ohler, U. and Schwarz, R.F.
iScience 27
(10): 110918.
18 October 2024
The recurrent atypical e8a2 BCR::ABL1 transcript with insertion of an inverted 55 base pair ABL1 intron 1b sequence: a detailed molecular analysis.
Burmeister, T., Bullinger, L. and le Coutre, P.
Acta Haematologica 146
(5): 413-418.
October 2023
Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.
Burmeister, T., Gröger, D., Gökbuget, N., Spriewald, B., Starck, M., Elmaagacli, A., Hoelzer, D., Keller, U. and Schwartz, S.
Scientific Reports 13
(1): 15167.
13 September 2023
Circulating metastasis associated in colon cancer 1 transcripts in gastric cancer patient plasma as diagnostic and prognostic biomarker.
Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Stein, U.
World Journal of Gastroenterology 21
(1): 333-341.
7 January 2015
Integration der Hyperthermie in chirurgisch-onkologische Techniken [Integration of hyperthermia into surgical oncological techniques].
Burock, S. and Schlag, P.M.
Onkologe 16
(11): 1079-1085.
November 2010
Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial.
Burock, S., Daum, S., Keilholz, U., Neumann, K., Walther, W. and Stein, U.
BMC Cancer 18
(1): 297.
15 March 2018
Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes.
Burridge, P.W., Diecke, S., Matsa, E., Sharma, A., Wu, H. and Wu, J.C.
Methods in Molecular Biology 1353
: 119-130.
2016
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes.
Burster, T., Beck, A., Tolosa, E., Marin-Esteban, V., Roetzschke, O., Falk, K., Lautwein, A., Reich, M., Brandenburg, J., Schwarz, G., Wiendl, H., Melms, A., Lehmann, R., Stevanovic, S., Kalbacher, H. and Driessen, C.
Journal of Immunology 172
(9): 5495-5503.
1 January 2004
Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro.
Burster, T., Becker, A., Poeschel, S., Oren, A., Baechle, D., Reich, M., Roetzschke, O., Falk, K., Boehm, B.O., Youssef, S., Kalbacher, H., Overkleeft, H., Tolosa, E. and Driessen, C.
Immunology 121
(1): 82-93.
May 2007
Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions.
Burster, T., Marin-Esteban, V., Boehm, B.O., Dunn, S., Roetzschke, O., Falk, K., Weber, E., Verhelst, S.H., Kalbacher, H. and Driessen, C.
Biochemical Pharmacology 74
(10): 1514-1523.
15 November 2007
Isolation and long-term cultivation of mouse alveolar macrophages.
Busch, C. J.-L., Favret, J., Geirsdóttir, L., Molawi, K. and Sieweke, M.H.
Bio-protocol 9
(14)
20 July 2019
Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas.
Busch, J., Ralla, B., Jung, M., Wotschofsky, Z., Trujillo-Arribas, E., Schwabe, P., Kilic, E., Fendler, A. and Jung, K.
Journal of Experimental & Clinical Cancer Research 34
(1): 61.
14 June 2015
Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M., Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M., Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A., Scheidereit, C., Butter, C., Felix, S.B., Otto, O., Luft, F.C., Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12
(6): 1653-1668.
December 2021
Arabidopsis KCBP interacts with AIR9 but stays in the cortical division zone throughout mitosis via its MyTH4-FERM domain.
Buschmann, H., Dols, J., Kopischke, S., Pena, E.J., Andrade-Navarro, M.A., Heinlein, M., Szymanski, D.B., Zachgo, S., Doonan, J.H. and Lloyd, C.W.
Journal of Cell Science 28
(11): 2033-2046.
1 June 2015
In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance.
Buschow, C., Charo, J., Anders, K., Loddenkemper, C., Jukica, A., Alsamah, W., Perez, C., Willimsky, G. and Blankenstein, T.
Journal of Immunology 184
(6): 2930-2938.
15 March 2010
Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA interdisciplinary expert consensus.
Buske, C., Dreyling, M., Alvarez-Larrán, A., Apperley, J., Arcaini, L., Besson, C., Bullinger, L., Corradini, P., Della Porta, M.G., Dimopoulos, M., D’Sa, S., Eich, H.T., Foà, R., Ghia, P., Gomes da Silva, M., Gribben, J., Hajek, R., Harrison, C., Heuser, M., Kiesewetter, B., Kiladjian, J.J., Kröger, N., Moreau, P., Passweg, J.R., Peyvandi, F., Rea, D., Ribera, J.M., Robak, T., San-Miguel, J.F., Santini, V., Sanz, G., Sonneveld, P., von Lilienfeld-Toal, M., Wendtner, C., Pentheroudakis, G. and Passamonti, F.
ESMO Open 7
(2): 100403.
April 2022
Sensitivity of tumor cells to proteasome inhibitors is associated with expression levels and composition of proteasome subunits.
Busse, A., Kraus, M., Na, I.K., Rietz, A., Scheibenbogen, C., Driessen, C., Blau, I.W., Thiel, E. and Keilholz, U.
Cancer 112
(3): 659-670.
1 February 2008
Expression of protein complexes using multiple E. coli protein co-expression systems: a benchmarking study.
Busso, D., Peleg, Y., Heidebrecht, T., Romier, C., Jacobovitch, Y., Dantes, A., Salim, L., Troesch, E., Schuetz, A., Heinemann, U., Folkers, G.E., Geerlof, A., Wilmanns, M., Polewacz, A., Quedenau, C., Büssow, K., Adamson, R., Blagova, E., Walton, J., Cartwright, J.L., Bird, L.E., Owens, R.J., Berrow, N.S., Wilson, K.S., Sussman, J.L., Perrakis, A. and Celie, P.H.
Journal of Structural Biology 175
(2): 159-170.
August 2011
Detection, isolation and partial characterization of an immunostimulating glycoprotein from Rhodococcus fascians.
Butschak, G., Karsten, U., Schelhaas, U., Ott, H., Emmendoerffer, A., Niemeyer, B., Helmholz, H. and Goletz, S.
International Immunopharmacology 6
(9): 1441-1450.
September 2006
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Bywater, M.J., Poortinga, G., Sanij, E., Hein, N., Peck, A., Cullinane, C., Wall, M., Cluse, L., Drygin, D., Anderes, K., Huser, N., Proffitt, C., Bliesath, J., Haddach, M., Schwaebe, M.K., Ryckman, D.M., Rice, W.G., Schmitt, C., Lowe, S.W., Johnstone, R.W., Pearson, R.B., McArthur, G.A. and Hannan, R.D.
Cancer Cell 22
(1): 51-65.
10 July 2012
Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I., Jaeschke, L., Nimptsch, K., Janke, J., Herrmann, P., Kobelt, D., Kielstein, H., Pischon, T. and Stein, U.
International Journal of Oncology 60
(2): 17.
February 2022
The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.
Bégay, V., Baumeier, C., Zimmermann, K., Heuser, A. and Leutz, A.
Scientific Reports 8
(1): 8417.
30 May 2018
Essential requirement of CCAAT/enhancer binding proteins in embryogenesis.
Bégay, V., Smink, J. and Leutz, A.
Molecular and Cellular Biology 24
(22): 9744-9751.
1 November 2004
Deregulation of the endogenous C/EBPβ LIP isoform predisposes to tumorigenesis.
Bégay, V., Smink, J.J., Loddenkemper, C., Zimmermann, K., Rudolph, C., Scheller, M., Steinemann, D., Leser, U., Schlegelberger, B., Stein, H. and Leutz, A.
Journal of Molecular Medicine 93
(1): 39-49.
January 2015
Analysis of the CDK4/6 cell cycle pathway in leiomyosarcomas as a potential target for inhibition by palbociclib.
Böhm, M.J., Marienfeld, R., Jäger, D., Mellert, K., von Witzleben, A., Brüderlein, S., Wittau, M., von Baer, A., Schultheiss, M., Mayer-Steinacker, R., Rücker, F.G., Möller, P., Bullinger, L. and Barth, T.F.E.
Sarcoma 2019
: 3914232.
21 January 2019
NF-κB signaling in tanycytes mediates inflammation-induced anorexia.
Böttcher, M., Müller-Fielitz, H., Sundaram, S.M., Gallet, S., Neve, V., Shionoya, K., Zager, A., Quan, N., Liu, X., Schmidt-Ullrich, R., Haenold, R., Wenzel, J., Blomqvist, A., Engblom, D., Prevot, V. and Schwaninger, M.
Molecular Metabolism 39
: 101022.
September 2020
Inferior outcomes of EU versus US patients treated with CD19 CAR-T for relapsed/refractory large B-cell lymphoma: association with differences in tumor burden, systemic inflammation, bridging therapy utilization, and CAR-T product use.
Bücklein, V., Perez, A., Rejeski, K., Iacoboni, G., Jurinovic, V., Holtick, U., Penack, O., Kharboutli, S., Blumenberg, V., Ackermann, J., Frölich, L., Johnson, G., Patel, K., Arciola, B., Mhaskar, R., Wood, A., Schmidt, C., Albanyan, O., Gödel, P., Hoster, E., Bullinger, L., Mackensen, A., Locke, F., von Bergwelt, M., Barba, P., Subklewe, M. and Jain, M.D.
HemaSphere 7
(8): e907.
August 2023
Gene therapy "Made in Germany": a historical perspective, analysis of the status quo, and recommendations for action by the German Society for Gene Therapy.
Büning, H., Fehse, B., Ivics, Z., Kochanek, S., Koehl, U., Kupatt, C., Mussolino, C., Nettelbeck, D.M., Schambach, A., Uckert, W., Wagner, E. and Cathomen, T.
Human Gene Therapy 32
(19-20): 987-996.
18 October 2021
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Cabezas-Wallscheid, N., Klimmeck, D., Hansson, J., Lipka, D.B., Reyes, A., Wang, Q., Weichenhan, D., Lier, A., von Paleske, L., Renders, S., Wünsche, P., Zeisberger, P., Brocks, D., Gu, L., Herrmann, C., Haas, S., Essers, M.A.G., Brors, B., Eils, R., Huber, W., Milsom, M.D., Plass, C., Krijgsveld, J. and Trumpp, A.
Cell Stem Cell 15
(4): 507-522.
2 October 2014
Single cell biology - a Keystone Symposia report.
Cable, J., Elowitz, M.B., Domingos, A.I., Habib, N., Itzkovitz, S., Hamidzada, H., Balzer, M.S., Yanai, I., Liberali, P., Whited, J., Streets, A., Cai, L., Stergachis, A.B., Hong, C.K.Y., Keren, L., Guilliams, M., Alon, U., Shalek, A.K., Hamel, R., Pfau, S.J., Raj, A., Quake, S.R., Zhang, N.R., Fan, J., Trapnell, C., Wang, B., Greenwald, N.F., Vento-Tormo, R., Santos, S.D.M., Spencer, S.L., Garcia, H.G., Arekatla, G., Gaiti, F., Arbel-Goren, R., Rulands, S., Junker, J.P., Klein, A.M., Morris, S.A., Murray, J.I., Galloway, K.E., Ratz, M. and Romeike, M.
Annals of the New York Academy of Sciences 1506
(1): 74-97.
December 2021
Cancer stem cells: advances in biology and clinical translation -- a Keystone Symposia report.
Cable, J., Pei, D., Reid, L.M., Wang, X.W., Bhatia, S., Karras, P., Melenhorst, J.J., Grompe, M., Lathia, J.D., Song, E., Kuo, C.J., Zhang, N., White, R.M., Ma, S.K., Ma, L., Chin, Y.R., Shen, M.M., Ng, I.O.L., Kaestner, K.H., Zhou, L., Sikandar, S., Schmitt, C.A., Guo, W., Wong, C.C.L., Ji, J., Tang, D.G., Dubrovska, A., Yang, C., Wiedemeyer, W.R. and Weissman, I.L.
Annals of the New York Academy of Sciences 1506
(1): 142–163.
December 2021
Human and mouse essentiality screens as a resource for disease gene discovery.
Cacheiro, P., Muñoz-Fuentes, V., Murray, S.A., Dickinson, M.E., Bucan, M., Nutter, L.M.J., Peterson, K.A., Haselimashhadi, H., Flenniken, A.M., Morgan, H., Westerberg, H., Konopka, T., Hsu, C.W., Christiansen, A., Lanza, D.G., Beaudet, A.L., Heaney, J.D., Fuchs, H., Gailus-Durner, V., Sorg, T., Prochazka, J., Novosadova, V., Lelliott, C.J., Wardle-Jones, H., Wells, S., Teboul, L., Cater, H., Stewart, M., Hough, T., Wurst, W., Sedlacek, R., Adams, D.J., Seavitt, J.R., Tocchini-Valentini, G., Mammano, F., Braun, R.E., McKerlie, C., Herault, Y., de Angelis, M.H., Mallon, A.M., Lloyd, K.C.K., Brown, S.D.M., Parkinson, H., Meehan, T.F. and Smedley, D.
Nature Communications 11
(1): 655.
31 January 2020
Sentinel node biopsy for the individualization of surgical strategy for cure of early-stage colon cancer.
Cahill, R.A., Bembenek, A., Sirop, S., Waterhouse, D.F., Schneider, W., Leroy, J., Wiese, D., Beutler, T., Bilchik, A., Saha, S. and Schlag, P.M.
Annals of Surgical Oncology 16
(8): 2170-2180.
August 2009
Genomic basis for RNA alterations in cancer.
Calabrese, C., Davidson, N.R., Demircioğlu, D., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., Soulette, C.M., Urban, L., Greger, L., Li, S., Liu, D., Perry, M.D., Xiang, Q., Zhang, F., Zhang, J., Bailey, P., Erkek, S., Hoadley, K.A., Hou, Y., Huska, M.R., Kilpinen, H., Korbel, J.O., Marin, M.G., Markowski, J., Nandi, T., Pan-Hammarström, Q., Pedamallu, C.S., Siebert, R., Stark, S.G., Su, H., Tan, P., Waszak, S.M., Yung, C., Zhu, S., Awadalla, P., Creighton, C.J., Meyerson, M., Ouellette, B.F.F., Wu, K., Yang, H., Brazma, A., Brooks, A.N., Göke, J., Rätsch, G., Schwarz, R.F., Stegle, O. and Zhang, Z.
Nature 578
(7793): 129-136.
6 February 2020
Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma.
Calado, D.P., Zhang, B., Srinivasan, L., Sasaki, Y., Seagal, J., Unitt, C., Rodig, S., Kutok, J., Tarakhovsky, A., Schmidt-Supprian, M. and Rajewsky, K.
Cancer Cell 18
(6): 580-589.
14 December 2010
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P., Sasaki, Y., Godinho, S.A., Pellerin, A., Köchert, K., Sleckman, B.P., de Alboran, I.M., Janz, M., Rodig, S. and Rajewsky, K.
Nature Immunology 13
(11): 1092-1100.
November 2012
Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly (ethylene glycol) shell.
Calderon, M., Welker, P., Licha, K., Fichtner, I., Graeser, R., Haag, R. and Kratz, F.
Journal of Controlled Release 151
(3): 295-301.
10 May 2011
Translational control of SCL-isoform expression in hematopoietic lineage choice.
Calkhoven, C.F., Mueller, C., Martin, R., Krosl, G., Hoang, T. and Leutz, A.
Genes & Development 17
(8): 959-964.
15 April 2003
53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Callen, E., Di Virgilio, M., Kruhlak, M.J., Nieto-Soler, M., Wong, N., Chen, H.T., Faryabi, R.B., Polato, F., Santos, M., Starnes, L.M., Wesemann, D.R., Lee, J.E., Tubbs, A., Sleckman, B.P., Daniel, J.A., Ge, K., Alt, F.W., Fernandez-Capetillo, O., Nussenzweig, M.C. and Nussenzweig, A.
Cell 153
(6): 1266-1280.
6 June 2013
Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Callen, E., Jankovic, M., Wong, N., Zha, S., Chen, H.T., Difilippantonio, S., Di Virgilio, M., Heidkamp, G., Alt, F.W., Nussenzweig, A. and Nussenzweig, M.
Molecular Cell 34
(3): 285-297.
15 May 2009
Detecting actively translated open reading frames in ribosome profiling data.
Calviello, L., Mukherjee, N., Wyler, E., Zauber, H., Hirsekorn, A., Selbach, M., Landthaler, M., Obermayer, B. and Ohler, U.
Nature Methods 13
(2): 165-170.
February 2016
Quantification of translation uncovers the functions of the alternative transcriptome.
Calviello, L., Hirsekorn, A. and Ohler, U.
Nature Structural & Molecular Biology 27
(8): 717-725.
August 2020
DDX3 depletion represses translation of mRNAs with complex 5' UTRs.
Calviello, L., Venkataramanan, S., Rogowski, K.J., Wyler, E., Wilkins, K., Tejura, M., Thai, B., Krol, J., Filipowicz, W., Landthaler, M. and Floor, S.N.
Nucleic Acids Research 49
(9): 5336-5350.
May 2021
In vitro and in vivo stability of the epsilon2zeta2 protein complex of the broad host-range Streptococcus pyogenes pSM19035 addiction system.
Camacho, A.G., Misselwitz, R., Behlke, J., Ayora, S., Welfle, K., Meinhart, A., Lara, B., Saenger, W., Welfle, H. and Alonso, J.C.
Biological Chemistry 383
(11): 1701-1713.
November 2002
Expression of CD175 (Tn), CD175s (sialosyl-Tn) and CD176 (Thomsen-Friedenreich antigen) on malignant human hematopoietic cells.
Cao, Y., Merling, A., Karsten, U., Goletz, S., Punzel, M., Kraft, R., Butschak, G. and Schwartz-Albiez, R.
International Journal of Cancer 123
(1): 89-99.
1 July 2008
Hyperphenylalaninemia and serotonin deficiency in Dnajc12-deficient mice.
Cao, Y., Popp, O., Milani, N., Qadri, F., Kühn, R., Mertins, P., Bader, M. and Alenina, N.
Communications Biology 7
(1): 1641.
18 December 2024
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish.
Cardeira-da-Silva, J., Wang, Q., Sagvekar, P., Mintcheva, J., Latting, S., Günther, S., Ramadass, R., Yekelchyk, M., Preussner, J., Looso, M., Junker, J.P. and Stainier, D.Y.R.
Nature Communications 15
(1): 3637.
29 April 2024
Differences in cell-type-specific responses to angiotensin II explain cardiac remodeling differences in C57BL/6 mouse substrains.
Cardin, S., Scott-Boyer, M.P., Praktiknjo, S., Jeidane, S., Picard, S., Reudelhuber, T.L. and Deschepper, C.F.
Hypertension 64
(5): 1040-1046.
November 2014
Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.
Carley, L.N., Mojica, J.P., Wang, B., Chen, C.Y., Lin, Y.P., Prasad, K.V.S.K, Chan, E., Hsu, C.W., Keith, R., Nuñez, C.L., Olson-Manning, C.F., Rushworth, C.A., Wagner, M.R., Wang, J., Yeh, P.M., Reichelt, M., Ghattas, K., Gershenzon, J., Lee, C.R. and Mitchell-Olds, T.
Nature Ecology & Evolution 5
: 1135-1144.
August 2021
The spatio-temporal pattern of testis organogenesis in mammals - insights from the mole.
Carmona, F.D., Lupianez, D.G., Martin, J.E., Burgos, M., Jimenez, R. and Zurita, F.
International Journal of Developmental Biology 53
(7): 1035-1044.
2009
SOX9 is not required for the cellular events of testicular organogenesis in XX mole ovotestes.
Carmona, F.D., Lupianez, D.G., Real, F.M., Burgos, M., Zurita, F. and Jimenez, R.
Journal of Experimental Zoology Part B : Molecular and Developmental Evolution 312
(7): 734-748.
15 November 2009
Proteomic signatures improve risk prediction for common and rare diseases.
Carrasco-Zanini, J., Pietzner, M., Davitte, J., Surendran, P., Croteau-Chonka, D.C., Robins, C., Torralbo, A., Tomlinson, C., Grünschläger, F., Fitzpatrick, N., Ytsma, C., Kanno, T., Gade, S., Freitag, D., Ziebell, F., Haas, S., Denaxas, S., Betts, J.C., Wareham, N.J., Hemingway, H., Scott, R.A. and Langenberg, C.
Nature Medicine 30
(9): 2489-2498.
September 2024
Single-cell lineage tracing approaches in hematology research: technical considerations.
Carrelha, J., Lin, D.S., Rodriguez-Fraticelli, A.E., Luis, T.C., Wilkinson, A.C., Cabezas-Wallscheid, N., Tremblay, C.S. and Haas, S.
Experimental Hematology 89
: 26-36.
September 2020
The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity.
Carriquí-Madroñal, B., Sheldon, J., Duven, M., Stegmann, C., Cirksena, K., Wyler, E., Zapatero-Belinchón, F.J., Vondran, F.W.R. and Gerold, G.
PLoS Pathogens 19
(11): e1011759.
15 November 2023
The alpha4beta1 and alpha5beta1 integrins mediate engraftment of granulocyte-colony-stimulating factor-mobilized human hematopoietic progenitor cells.
Carstanjen, D., Gross, A., Kosova, N., Fichtner, I. and Salama, A.
Transfusion 45
: 1192-1200.
1 July 2005
Detection of cell-free DNA in bronchial lavage fluid supernatants of patients with lung cancer.
Carstensen, T., Schmidt, B., Engel, E., Jandrig, B., Witt, C. and Fleischhacker, M.
Annals of the New York Academy of Sciences 1022
: 202-210.
1 June 2004
Enhanced properties of a benzimidazole benzylpyrazole lysine demethylase inhibitor: mechanism-of-action, binding site analysis, and activity in cellular models of prostate cancer.
Carter, D.M., Specker, E., Malecki, P.H., Przygodda, J., Dudaniec, K., Weiss, M.S., Heinemann, U., Nazaré, M. and Gohlke, U.
Journal of Medicinal Chemistry 64
(19): 14266-14282.
14 October 2021
Identification of a novel benzimidazole pyrazolone scaffold that inhibits KDM4 lysine demethylases and reduces proliferation of prostate cancer cells.
Carter, D.M., Specker, E., Przygodda, J., Neuenschwander, M., von Kries, J.P., Heinemann, U., Nazaré, M. and Gohlke, U.
SLAS Discovery 22
(7): 801-812.
1 August 2017
SRRM2 splicing factor modulates cell fate in early development.
Carvalho, S., Zea-Redondo, L., Tang, T.C.C., Stachel-Braum, P., Miller, D., Caldas, P., Kukalev, A., Diecke, S., Grosswendt, S., Grosso, A.R. and Pombo, A.
Biology Open 13
(4): bio060415.
April 2024
A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression.
Casado-Medrano, V., Barrio-Real, L., García-Rostán, G., Baumann, M., Rocks, O. and Caloca, M.J.
Oncotarget 7
(19): 28301-28319.
10 May 2016
Dynamo: a flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments.
Castaño-Díez, D., Kudryashev, M., Arheit, M. and Stahlberg, H.
Journal of Structural Biology 178
(2): 139-151.
May 2012
Dynamo Catalogue: geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms.
Castaño-Díez, D., Kudryashev, M. and Stahlberg, H.
Journal of Structural Biology 197
(2): 135-144.
February 2017
Management of busulfan-induced lung injury in pediatric patients with high-risk neuroblastoma.
Castelli, S., Thorwarth, A., van Schewick, C., Wendt, A., Astrahantseff, K., Szymansky, A., Lodrini, M., Veldhoen, S., Gratopp, A., Mall, M.A., Eggert, A. and Deubzer, H.E.
Journal of Clinical Medicine 13
(19): 5995.
8 October 2024
In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine.
Cayeux, S., Bukarica, B., Buschow, C., Charo, J., Bunse, M., Doerken, B. and Blankenstein, T.
Gene Therapy 14
(20): 1481-1491.
October 2007
The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription.
Cecere, G., Hoersch, S., Jensen, M.B., Dixit, S. and Grishok, A.
Molecular Cell 50
(6): 894-907.
27 June 2013
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N., Naumann, H., Ruzittu, S., Mah, N., Pongrac, I.M., Cozzitorto, C., Hommel, A., Andrade-Navarro, M.A., Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8
: 14127.
13 February 2017
Building a Healthcare Alliance for Resourceful Medicine Offensive Against Neoplasms in hematologY added value framework for hematologic malignancies: a comparative analysis of existing tools.
Cerisoli, F., Ali, F., Bereczky, T., Bolaños, N., Bullinger, L., Dhanasiri, S., Gallagher, J., Pérez, S.G., Geissler, J., Guillevic, Y., Harrison, K., Naoum, A., Portulano, C., Rodríguez Vicente, A.E., Schulze-Rath, R., Gómez, G.Y., Sanz, G. and Hernández Rivas, J.M.
Value in Health 25
(10): 1760-1767.
October 2022
Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.
Cerrone, M., Noorman, M., Lin, X., Chkourko, H., Liang, F.X., van der Nagel, R., Hund, T., Birchmeier, W., Mohler, P., van Veen, T.A., van Rijen, H.V. and Delmar, M.
Cardiovascular Research 95
(4): 460-468.
1 September 2012
Compound-SNE: comparative alignment of t-SNEs for multiple single-cell omics data visualization.
Cess, C.G. and Haghverdi, L.
Bioinformatics 40
(7): btae471.
July 2024
Multi-platform discovery of haplotype-resolved structural variation in human genomes.
Chaisson, M.J.P., Sanders, A.D., Zhao, X., Malhotra, A., Porubsky, D., Rausch, T., Gardner, E.J., Rodriguez, O.L., Guo, L., Collins, R.L., Fan, X., Wen, J., Handsaker, R.E., Fairley, S., Kronenberg, Z.N., Kong, X., Hormozdiari, F., Lee, D., Wenger, A.M., Hastie, A.R., Antaki, D., Anantharaman, T., Audano, P.A., Brand, H., Cantsilieris, S., Cao, H., Cerveira, E., Chen, C., Chen, X., Chin, C.S., Chong, Z., Chuang, N.T., Lambert, C.C., Church, D.M., Clarke, L., Farrell, A., Flores, J., Galeev, T., Gorkin, D.U., Gujral, M., Guryev, V., Heaton, W.H., Korlach, J., Kumar, S., Kwon, J.Y., Lam, E.T., Lee, J.E., Lee, J., Lee, W.P., Lee, S.P., Li, S., Marks, P., Viaud-Martinez, K., Meiers, S., Munson, K.M., Navarro, F.C.P., Nelson, B.J., Nodzak, C., Noor, A., Kyriazopoulou-Panagiotopoulou, S., Pang, A.W.C., Qiu, Y., Rosanio, G., Ryan, M., Stütz, A., Spierings, D.C.J., Ward, A., Welch, A.E., Xiao, M., Xu, W., Zhang, C., Zhu, Q., Zheng-Bradley, X., Lowy, E., Yakneen, S., McCarroll, S., Jun, G., Ding, L., Koh, C.L., Ren, B., Flicek, P., Chen, K., Gerstein, M.B., Kwok, P.Y., Lansdorp, P.M., Marth, G.T., Sebat, J., Shi, X., Bashir, A., Ye, K., Devine, S.E., Talkowski, M.E., Mills, R.E., Marschall, T., Korbel, J.O., Eichler, E.E. and Lee, C.
Nature Communications 10
(1): 1784.
16 April 2019
Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach.
Chakrabarti, P.P., Daumke, O., Suveyzdis, Y., Koetting, C., Gerwert, K. and Wittinghofer, A.
Journal of Molecular Biology 367
(4): 983-95.
6 April 2007
Comparing agent‐based delivery of DNA and PNA forced intercalation (FIT) probes for multicolor mRNA imaging.
Chamiolo, J., Fang, G.M., Hövelmann, F., Friedrich, D., Knoll, A., Loewer, A. and Seitz, O.
ChemBioChem 20
(4): 595-604.
15 February 2019
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R., Conrad, T., Stöber, M.C., Xu, R., Giurgiu, M., Rodriguez-Fos, E., Kasack, K., Brückner, L., van Leen, E., Helmsauer, K., Dorado Garcia, H., Stefanova, M.E., Hung, K.L., Bei, Y., Schmelz, K., Lodrini, M., Mundlos, S., Chang, H.Y., Deubzer, H.E., Sauer, S., Eggert, A., Schulte, J.H., Schwarz, R.F., Haase, K., Koche, R.P. and Henssen, A.G.
Nature Genetics 55
(5): 880-890.
May 2023
Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.
Chan, G., Cheung, L.S., Yang, W., Milyavsky, M., Sanders, A.D., Gu, S., Hong, W.X., Liu, A.X., Wang, X., Barbara, M., Sharma, T., Gavin, J., Kutok, J.L., Iscove, N.N., Shannon, K.M., Dick, J.E., Neel, B.G. and Braun, B.S.
Blood 117
(16): 4253-4261.
21 April 2011
Molecular recording of mammalian embryogenesis.
Chan, M.M., Smith, Z.D., Grosswendt, S., Kretzmer, H., Norman, T.M., Adamson, B., Jost, M., Quinn, J.J., Yang, D., Jones, M.G., Khodaverdian, A., Yosef, N., Meissner, A. and Weissman, J.S.
Nature 570
(7759): 77-82.
6 June 2019
Bax-dependent regulation of Bak by voltage-dependent anion channel 2.
Chandra, D., Choy, G., Daniel, P.T. and Tang, D.G.
Journal of Biological Chemistry 280
: 19051-19061.
1 January 2005
Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death.
Chandra, D., Choy, G., Deng, X., Bhatia, B., Daniel, P. and Tang, D.G.
Molecular and Cellular Biology 24
: 6592-6607.
1 January 2004
Determining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging.
Chang, S.Y.S., Dijkman, P.M., Wiessing, S.A. and Kudryashev, M.
Scientific Reports 13
: 11523.
17 July 2023
Visualizing the dynamic of adoptively transferred T cells during the rejection of large established tumors.
Charo, J., Perez, C., Buschow, C., Jukica, A., Czeh, M. and Blankenstein, T.
European Journal of Immunology 41
(11): 3187-3197.
November 2011
STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
Chatterjee, M., Jain, S., Stuehmer, T., Andrulis, M., Ungethuem, U., Kuban, R.J., Lorentz, H., Bommert, K., Topp, M., Kramer, D., Mueller-Hermelink, H. K., Einsele, H., Greiner, A. and Bargou, R.C.
Blood 109
(2): 720-728.
15 January 2007
The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma.
Chatterjee, M., Rancso, C., Stuehmer, T., Eckstein, N., Andrulis, M., Gerecke, C., Lorentz, H., Royer, H.D. and Bargou, R.C.
Blood 111
(7): 3714-3722.
1 April 2008
Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M., Stuehmer, T., Herrmann, P., Bommert, K., Doerken, B. and Bargou, R.C.
Blood 104
(12): 3712-3721.
1 January 2004
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Chee, J.M., Lanoue, L., Clary, D., Higgins, K., Bower, L., Flenniken, A., Guo, R., Adams, D.J., Bosch, F., Braun, R.E., Brown, S.D.M., Chin, H.J.G., Dickinson, M.E., Hsu, C.W., Dobbie, M., Gao, X., Galande, S., Grobler, A., Heaney, J.D., Herault, Y., de Angelis, M.H., Mammano, F., Nutter, L.M.J, Parkinson, H., Qin, C., Shiroishi, T., Sedlacek, R., Seong, J.K., Xu, Y., Brooks, B., McKerlie, C., Lloyd, K.C.K., Westerberg, H. and Moshiri, A.
BMC Biology 21
(1): 22.
3 February 2023
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
Chemi, F., Rothwell, D.G., McGranahan, N., Gulati, S., Abbosh, C., Pearce, S.P., Zhou, C., Wilson, G.A., Jamal-Hanjani, M., Birkbak, N., Pierce, J., Kim, C.S., Ferdous, S., Burt, D.J., Slane-Tan, D., Gomes, F., Moore, D., Shah, R., Al Bakir, M., Hiley, C., Veeriah, S., Summers, Y., Crosbie, P., Ward, S., Mesquita, B., Dynowski, M., Biswas, D., Tugwood, J., Blackhall, F., Miller, C., Hackshaw, A., Brady, G., Swanton, C. and Dive, C.
Nature Medicine 25
(10): 1534-1539.
October 2019
Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system.
Chen, X.T., Leisegang, M., Gavvovidis, I., Pollack, S.M., Lorenz, F.K.M., Schumacher, T.N., Daumke, O. and Blankenstein, T.
Frontiers in Immunology 15
: 1524629.
24 December 2024
The c-Myb functions as a downstream target of PDGF-mediated survival signal in vascular smooth muscle cells.
Chen, Y., Xu, H., Liu, J., Zhang, C., Leutz, A. and Mo, X.
Biochemical and Biophysical Research Communications 360
(2): 433-436.
24 August 2007
Structure of RyR1 in native membranes.
Chen, W. and Kudryashev, M.
EMBO Reports 21
(5): e49891.
6 May 2020
LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression.
Chen, W., Wang, F., Yu, X., Qi, J., Dong, H., Cui, B., Zhang, Q., Wu, Y., An, J., Ni, N., Liu, C., Han, Y., Zhang, S., Schmitt, C.A., Deng, J., Yu, Y. and Du, J.
Oncogene 43
(18): 1328-1340.
2 May 2024
Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X., Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214
(11): 3417-3433.
6 November 2017
Identification of 2-[4-[(4-methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers.
Cheng, X., Dimou, E., Alborzinia, H., Wenke, F., Goehring, A., Reuter, S., Mah, N., Fuchs, H., Andrade-Navarro, M.A., Adjaye, J., Gul, S., Harms, C., Utikal, J., Klipp, E., Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58
(12): 4976-4983.
25 June 2015
Ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4.
Cheng, X., Yoshida, H., Raoofi, D., Saleh, S., Alborzinia, H., Wenke, F., Goehring, A., Reuter, S., Mah, N., Fuchs, H.R., Andrade-Navarro, M.A., Adjaye, J., Gul, S., Utikal, J., Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58
(1): 5742-5750.
13 August 2015
Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.
Chevelkov, V., Faelber, K., Diehl, A., Heinemann, U., Oschkinat, H. and Reif, B.
Journal of Biomolecular NMR 31
(4): 295-310.
1 January 2005
Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R., Sternjak, A., Wend, P., Momma, S., Campos, B., Herrmann, I.M., Graf, D., Mitsiadis, T., Herold-Mende, C., Besser, D., Synowitz, M., Kettenmann, H. and Glass, R.
Brain 133
(Pt 7): 1961-1972.
July 2010
Immediate effects of reversible HTLV-I tax function: T-cell activation and apoptosis.
Chlichlia, K., Moldenhauer, G., Daniel, P.T., Busslinger, M., Gazzalo, L., Schirrmacher, V. and Khazaie, K.
Oncogene 10
(2): 269-277.
19 January 1995
c-Met is essential for wound healing in the skin.
Chmielowiec, J., Borowiak, M., Morkel, M., Stradal, T., Munz, B., Werner, S., Wehland, J., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177
(1): 151-162.
9 April 2007
miR-23~27~24 clusters control effector T cell differentiation and function.
Cho, S., Wu, C.J., Yasuda, T., Cruz, L.O., Khan, A.A., Lin, L.L., Nguyen, D.T., Miller, M., Lee, H.M., Kuo, M.L., Broide, D.H., Rajewsky, K., Rudensky, A.Y. and Lu, L.F.
Journal of Experimental Medicine 213
(2): 235-249.
8 February 2016
Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
Choi, I.K., Wang, Z., Ke, Q., Hong, M., Qian, Y., Zhao, X., Liu, Y., Kim, H.J., Ritz, J., Cantor, H., Rajewsky, K., Wucherpfennig, K.W. and Zhang, B.
Proceedings of the National Academy of Sciences of the United States of America 115
(4): E686-E695.
January 2018
Endothelial NF-κB blockade abrogates ANCA-induced GN.
Choi, M., Schreiber, A., Eulenberg-Gustavus, C., Scheidereit, C., Kamps, J. and Kettritz, R.
Journal of the American Society of Nephrology 28
(11): 3191-3204.
November 2017
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chong, C., Müller, M., Pak, H.S., Harnett, D., Huber, F., Grun, D., Leleu, M., Auger, A., Arnaud, M., Stevenson, B.J., Michaux, J., Bilic, I., Hirsekorn, A., Calviello, L., Simó-Riudalbas, L., Planet, E., Lubiński, J., Bryśkiewicz, M., Wiznerowicz, M., Xenarios, I., Zhang, L., Trono, D., Harari, A., Ohler, U., Coukos, G. and Bassani-Sternberg, M.
Nature Communications 11
(1): 1293.
10 March 2020
Development and validation of a three dimensional ultrasound based navigation system for tumor resection.
Chopra, S.S., Huenerbein, M., Eulenstein, S., Lange, T., Schlag, P.M. and Beller, S.
European Journal of Surgical Oncology 34
(4): 456-461.
April 2008
Rituximab in the management of post-transplantation lymphoproliferative disorder after solid organ transplantation: proceed with caution.
Choquet, S., Oertel, S., Leblond, V., Riess, H., Varoqueaux, N., Doerken, B. and Trappe, R.
Annals of Hematology 86
(8): 599-607.
August 2007
Structure of the active GGEEF domain of a diguanylate cyclase from Vibrio cholerae.
Chouhan, O.P., Roske, Y., Heinemann, U. and Biswas, S.
Biochemical and Biophysical Research Communications 523
(2): 287-292.
5 March 2020
Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F., Hablesreiter, R., Hoyer, K., Hennch, C., Maluck-Böttcher, A., Segler, A., Madadi, A., Frick, M., Bullinger, L., Briest, F. and Damm, F.
Leukemia 36
(4): 1102-1110.
April 2022
Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
Christen, F., Hoyer, K., Yoshida, K., Hou, H.A., Waldhueter, N., Heuser, M., Hills, R.K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W.C., Blau, I.W., Tang, J.L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Löwenberg, B., Linch, D.C., Bullinger, L., Valk, P.J.M., Tien, H.F., Gale, R.E., Ogawa, S. and Damm, F.
Blood 133
(10): 1140-1151.
7 March 2019
CRISPR/Cas9-mediated in vitro mutagenesis in GC-like B cells.
Chu, V.T., Graf, R. and Rajewsky, K.
Methods in Molecular Biology 1623
: 135-145.
2017
Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T., Graf, R., Wirtz, T., Weber, T., Favret, J., Li, X., Petsch, K., Tran, N.T., Sieweke, M.H., Berek, C., Kühn, R. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113
(44): 12514-12519.
1 November 2016
Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.
Chu, V.T., Weber, T., Graf, R., Sommermann, T., Petsch, K., Sack, U., Volchkov, P., Rajewsky, K. and Kühn, R.
BMC Biotechnology 16
(1): 4.
16 January 2016
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu, V.T., Weber, T., Wefers, B., Wurst, W., Sander, S., Rajewsky, K. and Kühn, R.
Nature Biotechnology 33
(5): 543-548.
May 2015
Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
Chumduri, C., Gillissen, B., Richter, A., Richter, A., Milojkovic, A., Overkamp, T., Mueller, A., Pott, C. and Daniel, P.T.
Journal of Molecular Medicine 93
(5): 559-572.
May 2015
Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response.
Churin, Y., Al Ghoul, L., Kepp, O., Meyer, T.E., Birchmeier, W. and Naumann, M.
Journal of Cell Biology 161
(2): 249-255.
28 April 2003
Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells.
Chyou, S., Benahmed, F., Chen, J., Kumar, V., Tian, S., Lipp, M. and Lu, T.T.
Journal of Immunology 187
(11): 5558-5567.
2 December 2011
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki, F., Bjordahl, R., Goodridge, J.P., Mahmood, S., Gaidarova, S., Abujarour, R., Davis, Z.B., Merino, A., Tuininga, K., Wang, H., Kumar, A., Groff, B., Witty, A., Bonello, G., Huffman, J., Dailey, T., Lee, T.T., Malmberg, K.J., Walcheck, B., Höpken, U., Rehm, A., Valamehr, B. and Miller, J.S.
Nature Communications 13
(1): 7341.
29 November 2022
Titer determination of Ad5 in blood: a cautionary note.
Cichon, G., Boeckh-Herwig, S., Kuemin, D., Hoffmann, C., Schmidt, H.H., Wehnes, E., Haensch, W., Schneider, U., Eckhardt, U., Burger, R. and Pring-Akerblom, P.
Gene Therapy 10
(12): 1012-1017.
June 2003
Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage.
Cichon, G., Willnow, T.E., Herwig, S., Uckert, W., Loeser, P., Schmidt, H.H., Benhidjeb, T., Schlag, P.M., Schnieders, F., Niedzielska, D. and Heeren, J.
Journal of Gene Medicine 6
(2): 166-175.
February 2004
Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C., Rom, A., Franke, V., Imami, K., Arrey, G., Terne, M., Woehler, A., Akalin, A., Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47
(5): 2560-2573.
18 March 2019
Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G., Bay, O., Zinno, J., Gutwein, M., Gan, H.H., Mayya, V.K., Chung, G., Chen, J.X., Fahs, H., Guan, Y., Duchaine, T.F., Selbach, M., Piano, F. and Gunsalus, K.C.
eLife 10
: e60833.
3 August 2021
Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E., Althoff, S., Ruß, J., Rosnev, S., Butze, M., Pühl, M., Frentsch, M., Bullinger, L. and Na, I.K.
International Journal of Molecular Sciences 23
(6): 3207.
16 March 2022
C/EBP-induced transdifferentiation reveals granulocyte-macrophage precursor-like plasticity of B cells.
Cirovic, B., Schönheit, J., Kowenz-Leutz, E., Ivanovska, J., Klement, C., Pronina, N., Bégay, V. and Leutz, A.
Stem Cell Reports 14
(8): 346-359.
14 February 2017
Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR.
Clauss, J., Obenaus, M., Miskey, C., Ivics, Z., Izsvák, Z., Uckert, W. and Bunse, M.
Human Gene Therapy 29
(5): 569-584.
May 2018
Den Weg konsequent weitergehen [The path consequently continues].
Clement, J., Hoeffken, K. and Schlag, P.M.
Onkologe 13
(10): 893.
October 2007
Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum.
Clerc, S., Hirsch, C., Oggier, D.M., Deprez, P., Jakob, C., Sommer, T. and Aebi, M.
Journal of Cell Biology 184
(1): 159-172.
12 January 2009
Low-grade glioma surgery in intraoperative magnetic resonance imaging: Results of a multicenter retrospective assessment of the German Study Group for Intraoperative Magnetic Resonance Imaging.
Coburger, J., Merkel, A., Scherer, M., Schwartz, F., Gessler, F., Roder, C., Pala, A., König, R., Bullinger, L., Nagel, G., Jungk, C., Bisdas, S., Nabavi, A., Ganslandt, O., Seifert, V., Tatagiba, M., Senft, C., Mehdorn, M., Unterberg, A.W., Rössler, K. and Wirtz, C.R.
Neurosurgery 78
(6): 775-86.
June 2016
Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation.
Cocciardi, S., Dolnik, A., Kapp-Schwoerer, S., Rücker, F.G., Lux, S., Blätte, T.J., Skambraks, S., Krönke, J., Heidel, F.H., Schnöder, T.M., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Teleanu, V., Göhring, G., Thol, F., Heuser, M., Ganser, A., Weber, D., Sträng, E., Kestler, H.A., Döhner, H., Bullinger, L. and Döhner, K.
Nature Communications 10
(1): 2031.
2 May 2019
The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.
Coel Arslan, S. and Scheidereit, C.
PLoS ONE 6
(10): e26069.
10 October 2011
miRNAs are essential for the regulation of the PI3K/AKT/FOXO pathway and receptor editing during B cell maturation.
Coffre, M., Benhamou, D., Riess, D., Blumenberg, L., Snetkova, V., Hines, M.J., Chakraborty, T., Bajwa, S., Jensen, K., Chong, M.M.W., Getu, L., Silverman, G.J., Blelloch, R., Littman, D.R., Calado, D., Melamed, D., Skok, J.A., Rajewsky, K. and Koralov, S.B.
Cell Reports 17
(9): 2271-2285.
22 November 2016
Skewed B cell differentiation affects lymphoid organogenesis but not T cell-mediated autoimmunity.
Colombo, E., Tentorio, P., Musio, S., Rajewsky, K., Pedotti, R., Casola, S. and Farina, C.
Clinical and Experimental Immunology 176
(1): 58-65.
April 2014
A roadmap to generate renewable protein binders to the human proteome.
Colwill, K. and Graeslund, S.
Nature Methods 8
(7): 551-558.
15 May 2011
Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes.
Company, C., Schmitt, M.J., Dramaretska, Y., Serresi, M., Kertalli, S., Jiang, B., Yin, J.A., Aguzzi, A., Barozzi, I. and Gargiulo, G.
Nature Communications 15
(1): 897.
5 February 2024
Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Consentius, P., Gohlke, U., Loll, B., Alings, C., Heinemann, U., Wahl, M.C. and Risse, T.
Physical Chemistry Chemical Physics 19
(31): 20723-20734.
9 August 2017
Tracking transient conformational states of T4 lysozyme at room temperature combining X-ray crystallography and site-directed spin labeling.
Consentius, P., Gohlke, U., Loll, B., Alings, C., Mueller, R., Heinemann, U., Kaupp, M., Wahl, M. and Risse, T.
Journal of the American Chemical Society 138
(39): 12868-12875.
5 October 2016
Internal dynamics of the 3-pyrroline-N-oxide ring in spin-labeled proteins.
Consentius, P., Loll, B., Gohlke, U., Alings, C., Müller, C., Müller, R., Teutloff, C., Heinemann, U., Kaupp, M., Wahl, M.C. and Risse, T.
Journal of Physical Chemistry Letters 8
(6): 1113-1117.
16 March 2017
Role of cranial radiotherapy for childhood T-cell acute lymphobalstic leukemia with high WBC count and good response to prednisone.
Conter, V., Schrappe, M., Arico, M., Reiter, A., Rizzari, C., Doerdelmann, M., Valsecchi, M.G., Zimmermann, M., Ludwig, W.D., Basso, G., Masera, G. and Riehm, H.
Journal of Clinical Oncology 15
(8): 2786-2791.
August 1997
PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data.
Corcoran, D.L., Georgiev, S., Mukherjee, N., Gottwein, E., Skalsky, R.L., Keene, J.D. and Ohler, U.
Genome Biology 12
(8): R79.
18 August 2011
Endothelial damage and dysfunction in acute graft-versus-host disease.
Cordes, S., Mokhtari, Z., Bartosova, M., Mertlitz, S., Riesner, K., Shi, Y., Mengwasser, J., Kalupa, M., McGeary, A., Schleifenbaum, J., Schrezenmeier, J., Bullinger, L., Diaz-Ricart, M., Palomo, M., Carrreras, E., Beutel, G., Schmitt, C.P., Beilhack, A. and Penack, O.
Haematologica 106
(8): 2147-2160.
1 August 2020
Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.
Corral, J., Forster, A., Thompson, S., Lampert, F., Kaneko, Y., Slater, R., Kroes, W.G., van der Schoot, C.E., Ludwig, W.D., Karpas, A., Pocock, C., Cotter, F. and Rabitts, T.H.
Proceedings of the National Academy of Sciences of the United States of America 90
(18): 8538-8542.
15 September 1993
A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis.
Coscia, F., Doll, S., Bech, J.M., Schweizer, L., Mund, A., Lengyel, E., Lindebjerg, J., Madsen, G.I., Moreira, J.M. and Mann, M.
Journal of Pathology 251
(1): 100-112.
May 2020
Multi-level proteomics identifies CT45 as a chemosensitivity mediator and immunotherapy target in ovarian cancer.
Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S.D., López-Méndez, B., Nilsson, J., Mund, A., Mann, M. and Curtis, M.
Cell 175
(1): 159-170.
20 September 2018
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Coscia, F., Watters, K.M., Curtis, M., Eckert, M.A., Chiang, C.Y., Tyanova, S., Montag, A., Lastra, R.R., Lengyel, E. and Mann, M.
Nature Communications 7
: 12645.
26 August 2016
Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription.
Cossa, G., Roeschert, I., Prinz, F., Baluapuri, A., Silveira Vidal, R., Schülein-Völk, C., Chang, Y.C., Ade, C.P., Mastrobuoni, G., Girard, C., Kumar, A., Wortmann, L., Walz, S., Lührmann, R., Kempa, S., Kuster, B., Wolf, E., Mumberg, D. and Eilers, M.
Molecular Cell 77
(6): 1322-1339.
19 March 2020
Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP.
Courtial, N., Smink, J.J., Kuvardina, O.N., Leutz, A., Goethert, J.R. and Lausen, J.
FASEB Journal 26
(2): 523-532.
February 2012
Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Creutzig, U., Harbott, J., Sperling, C., Ritter, J., Zimmermann, M., Loeffler, H., Riehm, H., Schellong, G. and Ludwig, W.D.
Blood 86
(8): 3097-3108.
1 October 1995
Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.
Cui, H., Bansal, V., Grunert, M., Malecova, B., Dall Agnese, A., Latella, L., Gatto, S., Ryan, T., Schulz, K., Chen, W., Dorn, C., Puri, P.L. and Sperling, S.R.
PLoS ONE 12
(6): e0179464.
13 June 2017
Hemostatic management in an infant with neuroblastoma and severe hemophilia B with extended half-life recombinant factor IX fusion protein.
Cuntz, F., Deubzer, H.E., Schulte, J.H., Nimtz-Talaska, A., Eggert, A. and Holzhauer, S.
Journal of Pediatric Hematology Oncology 44
(1): e246-e249.
1 January 2022
Cryoelectron tomography reveals periodic material at the inner side of subpellicular microtubules in apicomplexan parasites.
Cyrklaff, M., Kudryashev, M., Leis, A., Leonard, K., Baumeister, W., Menard, R., Meissner, M. and Frischknecht, F.
Journal of Experimental Medicine 204
(6): 1281-1287.
11 June 2007
The immune response to sporadic colorectal cancer in a novel mouse model.
Czeh, M., Loddenkemper, C., Shalapour, S., Schoen, C., Robine, S., Goldscheid, E., Stein, H., Schueler, T., Willimsky, G. and Blankenstein, T.
Oncogene 29
(50): 6591-6602.
16 December 2010
Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2.
D'Orazio, D., Besser, D., Marksitzer, R., Kunz, C., Hume, D.A., Kiefer, B. and Nagamine, Y.
Gene 201
(1-2): 179-187.
12 November 1997
Expression of genes controlling testicular development in adult testis of the seasonally breeding iberian mole.
Dadhich, R.K., Barrionuevo, F.J., Lupianez, D.G., Real, F.M., Burgos, M. and Jimenez, R.
Sexual Development 5
(2): 77-88.
March 2011
Identification of live germ-cell desquamation as a major mechanism of seasonal testis regression in mammals: a study in the Iberian mole (Talpa occidentalis).
Dadhich, R.K., Barrionuevo, F.J., Real, F.M., Lupiañez, D.G., Ortega, E., Burgos, M. and Jiménez, R.
Biology of Reproduction 88
(4): 101.
1 April 2013
RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.
Dahlmann, M., Okhrimenko, A., Marcinkowski, P., Osterland, M., Herrmann, P., Smith, J., Heizmann, C.W., Schlag, P.M. and Stein, U.
Oncotarget 5
(10): 3220-3233.
30 May 2014
Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.
Dahlmann, M., Sack, U., Herrmann, P., Lemm, M., Fichtner, I., Schlag, P.M. and Stein, U.
Oncotarget 3
(8): 783-797.
7 August 2012
RNA interference for antimetastatic therapy.
Dahlmann, M. and Stein, U.
Methods in Molecular Biology 1317
: 153-165.
2015
Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M., Monks, A., Harris, E.D., Kobelt, D., Osterland, M., Khaireddine, F., Herrmann, P., Kemmner, W., Burock, S., Walther, W., Shoemaker, R.H. and Stein, U.
Cancers 14
(1): 37.
2022
A bioinformatic pipeline to identify biomarkers for metastasis formation from RNA sequencing data.
Dahlmann, M. and Stein, U.S.
Methods in Molecular Biology 2294
: 221-238.
2021
Restoring treatment response in colorectal cancer cells by targeting MACC1-dependent ABCB1 expression in combination therapy.
Dahlmann, M., Werner, R., Kortüm, B., Kobelt, D., Walther, W. and Stein, U.
Frontiers in Oncology 10
: 599.
23 April 2020
Treatment of oesophageal anastomotic leaks by temporary stenting with self-expanding plastic stents.
Dai, Y.Y., Gretschel, S., Dudeck, O., Rau, B., Schlag, P.M. and Huenerbein, M.
British Journal of Surgery 96
(8): 887-891.
August 2009
Early bilirubinemia after allogeneic stem cell transplantation - an endothelial complication.
Dai, H., Penack, O., Radujkovic, A., Schult, D., Majer-Lauterbach, J., Blau, I.W., Bullinger, L., Jiang, S., Müller-Tidow, C., Dreger, P. and Luft, T.
Bone Marrow Transplantation 56
(7): 1573-1583.
July 2021
Novel targets of protoporphyrin-IX determined by gene expression analysis.
Dai, Y. and Kemmner, W.
International Journal of Clinical Oncology and Cancer Research 5
(3): 56-64.
September 2020
Genome-wide analysis of barrett's adenocarcinoma. a first step towards identifying patients at risk and developing therapeutic paths.
Dai, Y., Wang, Q., Gonzalez Lopez, A., Anders, M., Malfertheiner, P., Vieth, M. and Kemmner, W.
Translational Oncology 11
(1): 116-124.
February 2018
Covering hierarchical dirichlet mixture models on binary data to enhance genomic stratifications in onco-hematology.
Dall'Olio, D., Sträng, E., Turki, A.T., Tettero, J.M., Barbus, M., Schulze-Rath, R., Elicegui, J.M., Matteuzzi, T., Merlotti, A., Carota, L., Sala, C., Della Porta, M.G., Giampieri, E., Hernández-Rivas, J.M., Bullinger, L. and Castellani, G.
PLoS Computational Biology 20
(2): e1011299.
2 February 2024
Molekulare Grundlagen der zielgerichteten Tumortherapie [The molecular bases of targeted tumor therapy].
Daniel, P.
Onkologe 13
(1): 8-19.
January 2007
Grundlagen der molekularen Diagnostik und Therapie maligner Tumoren [Basics of molecular diagnostics and therapy of malignant tumors].
Daniel, P.T. and Doerken, B.
Internist 46
(8): 835-846.
12 July 2005
Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T., Kroidl, A., Kopp, J., Sturm, I., Moldenhauer, G., Doerken, B. and Pezzutto, A.
Blood 92
(12): 4750-4757.
15 December 1998
Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.
Daniel, P.T., Kroidl, A., Cayeux, S., Bargou, R.C., Blankenstein, T. and Doerken, B.
Journal of Immunology 159
(8): 3808-3815.
15 October 1997
PankoMab: a potent new generation anti-tumour MUC1 antibody.
Danielczyk, A., Stahn, R., Faulstich, D., Loeffler, A., Maerten, A., Karsten, U. and Goletz, S.
Cancer Immunology Immunotherapy 55
(11): 1337-1347.
November 2006
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Danielli, S.G., Porpiglia, E., De Micheli, A.J., Navarro, N., Zellinger, M.J., Bechtold, I., Kisele, S., Volken, L., Marques, J.G., Kasper, S., Bode, P.K., Henssen, A.G., Gürgen, D., Delattre, O., Surdez, D., Roma, J., Bühlmann, P., Blau, H.M., Wachtel, M. and Schäfer, B.W.
Science Advances 9
(6): eade9238.
10 February 2023
The pierced lasso topology leptin has a bolt on dynamic domain composed by the disordered loops I and III.
Danielsson, J., Noel, J.K., Simien, J.M., Duggan, B.M., Oliveberg, M., Onuchic, J.N., Jennings, P.A. and Haglund, E.
Journal of Molecular Biology 432
(9): 3050-3063.
17 April 2020
Control of gene editing by manipulation of DNA repair mechanisms.
Danner, E., Bashir, S., Yumlu, S., Wurst, W., Wefers, B. and Kühn, R.
Mammalian Genome 28
(7-8): 262-274.
August 2017
A homology independent sequence replacement strategy in human cells using a CRISPR nuclease.
Danner, E., Lebedin, M., de la Rosa, K. and Kühn, R.
Open Biology 11
(1): 200283.
January 2021
T cells engineered to express a T-cell receptor specific for glypican-3 recognize and kill hepatoma cells in vitro and in mice.
Dargel, C., Bassani-Sternberg, M., Hasreiter, J., Zani, F., Bockmann, J.H., Thiele, F., Bohne, F., Wisskirchen, K., Wilde, S., Sprinzl, M.F., Schendel, D.J., Krackhardt, A.M., Uckert, W., Wohlleber, D., Schiemann, M., Stemmer, K., Heikenwälder, M., Busch, D.H., Richter, G., Mann, M. and Protzer, U.
Gastroenterology 149
(4): 1042-1052.
October 2015
GPR56 contributes to the development of acute myeloid leukemia in mice.
Daria, D., Kirsten, N., Muranyi, A., Mulaw, M., Ihme, S., Kechter, A., Hollnagel, M., Bullinger, L., Döhner, K., Döhner, H., Feuring-Buske, M. and Buske, C.
Leukemia 30
(8): 1734-1741.
August 2016
Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture.
Dasgupta, S., Dayagi, D.Y., Haimovich, G., Wyler, E., Olender, T., Singer, R.H., Landthaler, M. and Gerst, J.E.
eLife 12
: e83584.
30 May 2023
Generation of an antibody against the protein phosphatase 1 inhibitor KEPI and characterization of the epitope.
Daskalow, K., Boisguerin, P., Jandrig, B., Van Landeghem, F.K., Volkmer, R., Micheel, B. and Schenk, J.A.
Anticancer Research 30
(5): 1573-1578.
May 2010
Epitope mapping of antibodies against S-tagged fusion proteins and molecular weight markers.
Daskalow, K., Boisguerin, P., Jandrig, B., Volkmer, R., Micheel, B. and Schenk, J.A.
Bioscience, Biotechnology, and Biochemistry 72
(2): 346-351.
February 2008
Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module.
Daumke, O., Gao, S., von der Malsburg, A., Haller, O. and Kochs, G.
Small GTPases 1
(1): 62-64.
July 2010
Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
Daumke, O., Lundmark, R., Vallis, Y., Martens, S., Butler, P.J.G. and McMahon, H.T.
Nature 449
(7164): 923-927.
3 October 2007
Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains.
Daumke, O. and Knittler, M.R.
European Journal of Biochemistry 268
(17): 4776-86.
September 2001
The GTPase-activating protein Rap1GAP uses a catalytic asparagine.
Daumke, O., Weyand, M., Chakrabarti, P.P., Vetter, I.R. and Wittinghofer, A.
Nature 429
(6988): 197-201.
13 May 2004
Purification, crystallization and preliminary structural characterization of human Rap1GAP.
Daumke, O., Wittinghofer, A. and Weyand, M.
Acta Crystallographica Section D : Structural Biology 60
(Pt 4): 752-4.
April 2004
Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.
Dawson, M.A., Gudgin, E.J., Horton, S.J., Giotopoulos, G., Meduri, E., Robson, S., Cannizzaro, E., Osaki, H., Wiese, M., Putwain, S., Fong, C.Y., Grove, C., Craig, J., Dittmann, A., Lugo, D., Jeffrey, P., Drewes, G., Lee, K., Bullinger, L., Prinjha, R.K., Kouzarides, T., Vassiliou, G.S. and Huntly, B.J.P.
Leukemia 28
(2): 311-320.
February 2014
Systematic benchmarking of single-cell ATAC-sequencing protocols.
De Rop, F.V., Hulselmans, G., Flerin, C., Soler-Vila, P., Rafels, A., Christiaens, V., González-Blas, C.B., Marchese, D., Caratù, G., Poovathingal, S., Rozenblatt-Rosen, O., Slyper, M., Luo, W., Muus, C., Duarte, F., Shrestha, R., Bagdatli, S.T., Corces, M.R., Mamanova, L., Knights, A., Meyer, K.B., Mulqueen, R., Taherinasab, A., Maschmeyer, P., Pezoldt, J., Lambert, C.L.G., Iglesias, M., Najle, S.R., Dossani, Z.Y., Martelotto, L.G., Burkett, Z., Lebofsky, R., Martin-Subero, J.I., Pillai, S., Sebé-Pedrós, A., Deplancke, B., Teichmann, S.A., Ludwig, L.S., Braun, T.P., Adey, A.C., Greenleaf, W.J., Buenrostro, J.D., Regev, A., Aerts, S. and Heyn, H.
Nature Biotechnology 42
(6): 916-926.
June 2024
Mutant FUS and ELAVL4 (HuD) aberrant crosstalk in amyotrophic lateral sclerosis.
De Santis, R., Alfano, V., de Turris, V., Colantoni, A., Santini, L., Garone, M.G., Antonacci, G., Peruzzi, G., Sudria-Lopez, E., Wyler, E., Anink, J.J., Aronica, E., Landthaler, M., Pasterkamp, R.J., Bozzoni, I. and Rosa, A.
Cell Reports 27
(13): 3818-3831.
25 June 2019
TIM-3 and CEACAM1 do not interact in cis and in trans.
De Sousa Linhares, A., Kellner, F., Jutz, S., Zlabinger, G.J., Gabius, H.J., Huppa, J.B., Leitner, J. and Steinberger, P.
European Journal of Immunology 50
(8): 1126-1141.
August 2020
Suspension medium influences interaction of mesenchymal stromal cells with endothelium and pulmonary toxicity after transplantation in mice.
Deak, E., Ruester, B., Keller, L., Eckert, K., Fichtner, I., Seifried, E. and Henschler, R.
Cytotherapy 12
(2): 260-264.
April 2010
Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues.
Debes, G.F., Arnold, C.N., Young, A.J., Krautwald, S., Lipp, M., Hay, J.B. and Butcher, E.C.
Nature Immunology 6
(9): 889-894.
14 August 2005
In vivo differentiated cytokine-producing CD4+ T cells express functional CCR7.
Debes, G.F., Höpken, U.E. and Hamann, A.
Journal of Immunology 168
(11): 5441-5447.
1 June 2002
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Decaesteker, B., Denecker, G., Van Neste, C., Dolman, E.M., Van Loocke, W., Gartlgruber, M., Nunes, C., De Vloed, F., Depuydt, P., Verboom, K., Rombaut, D., Loontiens, S., De Wyn, J., Kholosy, W.M., Koopmans, B., Essing, A.H.W., Herrmann, C., Dreidax, D., Durinck, K., Deforce, D., van Nieuwerburgh, F., Henssen, A., Versteeg, R., Boeva, V., Schleiermacher, G., van Nes, J., Mestdagh, P., Vanhauwaert, S., Schulte, J.H., Westermann, F., Molenaar, J.J., De Preter, K. and Speleman, F.
Nature Communications 9
(1): 4866.
19 November 2018
GP130 activation induces myeloma and collaborates with MYC.
Dechow, T., Steidle, S., Götze, K.S., Rudelius, M., Behnke, K., Pechloff, K., Kratzat, S., Bullinger, L., Fend, F., Soberon, V., Mitova, N., Li, Z., Thaler, M., Bauer, J., Pietschmann, E., Albers, C., Grundler, R., Schmidt-Supprian, M., Ruland, J., Peschel, C., Duyster, J., Rose-John, S., Bassermann, F. and Keller, U.
Journal of Clinical Investigation 124
(12): 5263-5274.
1 December 2014
Thyrotropin receptor-specific lymphocytes in adenovirus-TSHR-immunized native and human leukocyte antigen-DR3-transgenic mice and in Graves' disease patient blood.
Degen, H., Gavvovidis, I., Blankenstein, T., Uhland, K. and Ungerer, M.
Thyroid 31
(6): 950-963.
June 2021
Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism.
Degiacomi, M.T., Iacovache, I., Pernot, L., Chami, M., Kudryashev, M., Stahlberg, H., van der Goot, F.G. and Dal Peraro, M.
Nature Chemical Biology 9
(10): 623-629.
October 2013
Self-organization of human embryonic stem cells on micropatterns.
Deglincerti, A., Etoc, F., Guerra, M.C., Martyn, I., Metzger, J., Ruzo, A., Simunovic, M., Yoney, A., Brivanlou, A.H., Siggia, E. and Warmflash, A.
Nature Protocols 11
(11): 2223-2232.
November 2016
Random focusing of tsunami waves.
Degueldre, H., Metzger, J.J., Geisel, T. and Fleischmann, R.
Nature Physics 12
(3): 259-262.
March 2016
Channeling of branched flow in weakly scattering anisotropic media.
Degueldre, H., Metzger, J.J., Schultheis, E. and Fleischmann, R.
Physical Review Letters 118
(2): 024301.
13 January 2017
Interleukin-7 modulates anti-tumor CD8+ T cell responses via its action on host cells.
Deiser, K., Stoycheva, D., Bank, U., Blankenstein, T. and Schüler, T.
PLoS ONE 11
(7): e0159690.
22 July 2016
The MYCmRNA3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.
Dejure, F.R., Royla, N., Herold, S., Kalb, J., Walz, S., Ade, C.P., Mastrobuoni, G., Vanselow, J.T., Schlosser, A., Wolf, E., Kempa, S. and Eilers, M.
EMBO Journal 36
(13): 1854-1868.
3 July 2017
Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney.
Dekel, B., Metsuyanim, S., Schmidt-Ott, K.M., Fridman, E., Jacob-Hirsch, J., Simon, A., Pinthus, J., Mor, Y., Barasch, J., Amariglio, N. and Reisner, Y.
Cancer Research 66
(12): 6040-6049.
15 June 2006
Small-molecule inhibition of APT1 affects Ras localization and signaling.
Dekker, F.J., Rocks, O., Vartak, N., Menninger, S., Hedberg, C., Balamurugan, R., Wetzel, S., Renner, S., Gerauer, M., Schoelermann, B., Rusch, M., Kramer, J.W., Rauh, D., Coates, G.W., Brunsveld, L., Bastiaens, P.I. and Waldmann, H.
Nature Chemical Biology 6
(6): 449-456.
June 2010
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V., Berruezo-Llacuna, M., Altwasser, R., Winkler, W., Sundaravinayagam, D., Balasubramanian, S., Caganova, M., Graf, R., Rahjouei, A., Henke, M.T., Driesner, M., Keller, L., Prigione, A., Janz, M., Akalin, A. and Di Virgilio, M.
Journal of Experimental Medicine 217
(10): e20200137.
5 October 2020
The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V., Rosen, D.B., Wang, Q., Gazumyan, A., Pai, J.A., Oliveira, T.Y., Sundaravinayagam, D., Zhang, W., Andreani, M., Keller, L., Kieffer-Kwon, K.R., Pękowska, A., Jung, S., Driesner, M., Subbotin, R.I., Casellas, R., Chait, B.T., Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72
(4): 636-649.
15 November 2018
Stage-specific metabolic features of differentiating neurons: implications for toxicant sensitivity.
Delp, J., Gutbier, S., Cerff, M., Zasada, C., Niedenführ, S., Zhao, L., Smirnova, L., Hartung, T., Borlinghaus, H., Schreiber, F., Bergemann, J., Gätgens, J., Beyss, M., Azzouzi, S., Waldmann, T., Kempa, S., Nöh, K. and Leist, M.
Toxicology and Applied Pharmacology 354
: 64-80.
1 September 2018
The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3β interaction protein (GSKIP) regulates β-catenin through its interactions with both protein kinase A (PKA) and GSK3β.
Dema, A., Schröter, M.F., Perets, E., Skroblin, P., Moutty, M.C., Deàk, V.A., Birchmeier, W. and Klussmann, E.
Journal of Biological Chemistry 291
(37): 19618-19630.
9 September 2016
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P., Newman, A.G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., Kleinau, G., Derkow, K., Richard, B.C., Schipke, C., Scheidereit, C., Stachelscheid, H., Golenbock, D., Peters, O., Coleman, M., Heppner, F.L., Scheerer, P., Tarabykin, V., Ruprecht, K., Izsvák, Z., Mayer, J. and Lehnardt, S.
JCI Insight 5
(7): e131093.
9 April 2020
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Demel, U.M., Böger, M., Yousefian, S., Grunert, C., Zhang, L., Hotz, P.W., Gottschlich, A., Köse, H., Isaakidis, K., Vonficht, D., Grünschläger, F., Rohleder, E., Wagner, K., Dönig, J., Igl, V., Brzezicha, B., Baumgartner, F., Habringer, S., Löber, J., Chapuy, B., Weidinger, C., Kobold, S., Haas, S., Busse, A.B., Müller, S., Wirth, M., Schick, M. and Keller, U.
Journal of Clinical Investigation 132
(9): e152383.
2 May 2022
A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo.
Demel, U.M., Lutz, R., Sujer, S., Demerdash, Y., Sood, S., Grünschläger, F., Kuck, A., Werner, P., Blaszkiewicz, S., Uckelmann, H.J., Haas, S. and Essers, M.
Blood Advances 6
(11): 3513-3528.
10 June 2022
Small molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy.
Demel, U.M., Wirth, M., Yousefian, S., Zhang, L., Isaakidis, K., Dönig, J., Böger, M., Singh, N., Köse, H., Haas, S., Müller, S., Schick, M. and Keller, U.
Haematologica 108
(2): 555-567.
February 2023
Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S., Bittner, A., Frick, M., Kase, J., Hoffmann, J., Trenker, C., Keller, U., Bogner, C., Hüttmann, A., Dürig, J., Janz, M., Mathas, S., Marks, R., Krohn, U., Na, I.K., Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 63
(1): 84-92.
January 2022
A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response.
Denker, S., Bittner, A., Na, I.K., Kase, J., Frick, M., Anagnostopoulos, I., Hummel, M. and Schmitt, C.A.
International Journal of Hematologic Oncology 8
(4): IJH20.
19 December 2019
Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference.
Denkert, C., Fuerstenberg, A., Daniel, P.T., Koch, I., Koebel, M., Weichert, W., Siegert, A. and Hauptmann, S.
Oncogene 22
(54): 8653-8661.
27 November 2003
Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.
Denkinger, C.M., Janssen, M., Schäkel, U., Gall, J., Leo, A., Stelmach, P., Weber, S.F., Krisam, J., Baumann, L., Stermann, J., Merle, U., Weigand, M.A., Nusshag, C., Bullinger, L., Schrezenmeier, J.F., Bornhäuser, M., Alakel, N., Witzke, O., Wolf, T., Vehreschild, M.J.G.T., Schmiedel, S., Addo, M.M., Herth, F., Kreuter, M., Tepasse, P.R., Hertenstein, B., Hänel, M., Morgner, A., Kiehl, M., Hopfer, O., Wattad, M.A., Schimanski, C.C., Celik, C., Pohle, T., Ruhe, M., Kern, W.V., Schmitt, A., Lorenz, H.M., Souto-Carneiro, M., Gaeddert, M., Halama, N., Meuer, S., Kräusslich, H.G., Müller, B., Schnitzler, P., Parthé, S., Bartenschlager, R., Gronkowski, M., Klemmer, J., Schmitt, M., Dreger, P., Kriegsmann, K., Schlenk, Ri.F. and Müller-Tidow, C.
Nature Cancer 4
(1): 96-107.
January 2023
Hexosamine pathway metabolites enhance protein quality control and prolong life.
Denzel, M.S., Storm, N.J., Gutschmidt, A., Baddi, R., Hinze, Y., Jarosch, E., Sommer, T., Hoppe, T. and Antebi, A.
Cell 156
(6): 1167-1178.
13 March 2014
Third-generation anti-CD19 CAR T cells for relapsed/refractory chronic lymphocytic leukemia: a phase 1/2 study.
Derigs, P., Schubert, M.L., Dreger, P., Schmitt, A., Yousefian, S., Haas, S., Röthemeier, C., Neuber, B., Hückelhoven-Krauss, A., Brüggemann, M., Bernhard, H., Kobbe, G., Lindemann, A., Rummel, M., Michels, B., Korell, F., Ho, A.D., Müller-Tidow, C. and Schmitt, M.
Leukemia 38
(11): 2419-2428.
November 2024
Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E., Herzog, S., Labi, V., Yasuda, T., Köchert, K., Janz, M., Villunger, A., Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113
(18): 5065-5070.
3 May 2016
Elevated Flt3L predicts long-term survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms.
Detjen, K.M., Otto, R., Giesecke, Y., Geisler, L., Riemer, P., Jann, H., Grötzinger, C., Sers, C., Pascher, A., Lüdde, T., Leser, U., Wiedenmann, B., Sigal, M., Tacke, F., Roderburg, C. and Hammerich, L.
Cancers 13
(17): 4463.
1 September 2021
Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells.
Deubzer, H., Busche, B., Rönndahl, G., Eikel, D., Michaelis, M., Cinatl, J., Schulze, S., Nau, H. and Witt, O.
Leukemia Research 30
(9): 1167-1175.
September 2006
„Liquid biopsies“ als neue Diagnostikplattform in der pädiatrischen Onkologie [Liquid biopsies as a new diagnostic platform in pediatric oncology].
Deubzer, H.E., Eggert, A. and Pajtler, K. W.
Onkologe 27
(5): 458-463.
May 2021
Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro.
Deubzer, H.E., Ehemann, V., Kulozik, A.E., Westermann, F., Savelyeva, L., Kopp-Schneider, A., Riester, D., Schwab, M. and Witt, O.
Cancer Letters 264
(1): 21-28.
8 June 2008
Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.
Deubzer, H.E., Ehemann, V., Westermann, F., Heinrich, R., Mechtersheimer, G., Kulozik, A.E., Schwab, M. and Witt, O.
International Journal of Cancer 122
(8): 1891-900.
15 April 2008
Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae.
Deubzer, H.E., Obaro, S.K., Newman, V.O., Adegbola, R.A., Greenwood, B.M. and Henderson, D.C.
Journal of Infectious Diseases 190
(10): 1758-1761.
15 November 2004
HDAC11 is a novel drug target in carcinomas.
Deubzer, H.E., Schier, M.C., Oehme, I., Lodrini, M., Haendler, B., Sommer, A. and Witt, O.
International Journal of Cancer 132
(9): 2200-2208.
1 May 2013
HMGXB4 targets Sleeping Beauty transposition to germinal stem cells.
Devaraj, A., Singh, M., Narayanavari, S.A., Yong, G., Chen, J., Wang, J., Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z., Raskó, T., Radscheit, K., Selbach, M., Ivics, Z. and Izsvak, Z.
International Journal of Molecular Sciences 24
(8): 7283.
14 April 2023
Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress.
Devos, S., Van Putte, W., Vitse, J., Van Driessche, G., Stremersch, S., Van Den Broek, W., Raemdonck, K., Braeckmans, K., Stahlberg, H., Kudryashev, M., Savvides, S.N. and Devreese, B.
Environmental Microbiology 19
(10): 3930-3937.
October 2017
The BTB/POZ domain targets the LAZ3/BCL6 oncoprotein to nuclear dots and mediates homomerisation in vivo.
Dhordain, P., Albagli, O., Ansieau, S., Koken, M., Deweindt, C., Quief, S., Lantoine, D., Leutz, A., Kerckaert, J.P. and Leprince, D.
Oncogene 11
(12): 2689-2697.
21 December 1995
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.
Di Micco, R., Sulli, G., Dobreva, M., Liontos, M., Botrugno, O.A., Gargiulo, G., dal Zuffu, R., Matti, V., d'Ario, G., Montani, E., Mercurio, C., Hahn, W.C., Gorgoulis, V., Minucci, S. and d'Adda di Fagagna, F.
Nature Cell Biology 13
(3): 292-302.
March 2011
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Di Virgilio, M., Callen, E., Yamane, A., Zhang, W., Jankovic, M., Gitlin, A.D., Feldhahn, N., Resch, W., Oliveira, T.Y., Chait, B.T., Nussenzweig, A., Casellas, R., Robbiani, D.F. and Nussenzweig, M.C.
Science 339
(6120): 711-715.
8 February 2013
PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin.
Di Virgilio, M., Ying, C.Y. and Gautier, J.
DNA Repair 8
(11): 1311-1320.
2 November 2009
Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11.
Di Virgilio, M. and Gautier, J.
Journal of Cell Biology 171
(5): 765-771.
5 December 2005
Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.
Dias D'Andréa, E., Roske, Y., de Oliveira, G.A.P., Cremer, N., Diehl, A., Schmieder, P., Heinemann, U., Oschkinat, H. and Ricardo Pires, J.
Journal of Structural Biology 211
(2): 107536.
1 August 2020
Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies.
Diaz Miqueli, A., Rolff, J., Lemm, M., Fichtner, I., Perez, R. and Montero, E.
British Journal of Cancer 100
(6): 950-958.
24 March 2009
Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.
Dick, A., Graf, L., Olal, D., von der Malsburg, A., Gao, S., Kochs, G. and Daumke, O.
Journal of Biological Chemistry 290
(20): 12779-12792.
15 May 2015
Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly.
Dick, A., Mikirtumov, V., Fuchs, J., Krupp, F., Olal, D., Bendl, E., Sprink, T., Diebolder, C., Kudryashev, M., Kochs, G., Roske, Y. and Daumke, O.
Structure 32
(8): 1068-1078.
8 August 2024
Enhancement of tumour-specific immune responses in vivo by 'MHC Loading-Enhancer' (MLE).
Dickhaut, K., Hoepner, S., Eckhard, J., Wiesmueller, K.H., Schindler, L., Jung, G., Falk, K. and Roetzschke, O.
PLoS ONE 4
(9): e6811.
7 September 2009
HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy.
Dickson, G.J., Liberante, F.G., Kettyle, L.M., O'Hagan, K.A., Finnegan, D.P.J., Bullinger, L., Geerts, D., McMullin, M.F., Lappin, T.R.J., Mills, K.I. and Thompson, A.
Haematologica 98
(8): 1216-25.
August 2013
FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells.
Diecke, S., Quiroga-Negreira, A., Redmer, T. and Besser, D.
Cells Tissues Organs 188
(1-2): 52-61.
July 2008
Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
Dieckmann, S., Strohmeyer, A., Willershäuser, M., Maurer, S.F., Wurst, W., Marschall, S., Hrabě de Angelis, M., Kühn, R., Worthmann, A., Fuh, M.M., Heeren, J., Köhler, N., Pauling, J.K. and Klingenspor, M.
American Journal of Physiology Endocrinology and Metabolism 322
(2): E85-E100.
February 2022
Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkins disease.
Diehl, V., Franklin, J., Pfreundschuh, M., Lathan, B., Paulus, U., Hasenclever, D., Tesch, H., Herrmann, R., Doerken, B., Mueller-Hermelink, H.K., Duehmke, E. and Loeffler, M.
New England Journal of Medicine 348
(24): 2386-2395.
12 June 2003
Structural changes of TasA in biofilm formation of Bacillus subtilis.
Diehl, A., Roske, Y., Ball, L., Chowdhury, A., Hiller, M., Molière, N., Kramer, R., Stöppler, D., Worth, C.L., Schlegel, B., Leidert, M., Cremer, N., Erdmann, N., Lopez, D., Stephanowitz, H., Krause, E., van Rossum, B.J., Schmieder, P., Heinemann, U., Turgay, K., Akbey, Ü. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 115
(13): 3237-3242.
27 March 2018
Differentiation of effector/memory V ae 2 T cells and migratory routes in lymph nodes or inflammatory sites.
Dieli, F., Poccia, F., Lipp, M., Sireci, G., Caccamo, N., Di Sano, C. and Salerno, A.
Journal of Experimental Medicine 198
(3): 391-397.
4 August 2003
Composition, formation, and regulation of the cytosolic c-ring, a dynamic component of the type III secretion injectisome.
Diepold, A., Kudryashev, M., Delalez, N.J., Berry, R.M. and Armitage, J.P.
PLoS Biology 13
(1): e1002039.
15 January 2015
Reconstruction of optical properties of phantom and breast lesion in vivo from paraxial scanning data.
Dierkes, T., Grosenick, D., Moesta, K.T., Moeller, M., Schlag, P.M., Rinneberg, H. and Arridge, S.
Physics in Medicine and Biology 50
: 2519-2542.
1 January 2005
Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S., Company, C., Song, K., Lowenstein, E.D., Riedel, L., Birchmeier, C., Gargiulo, G. and Zampieri, N.
Nature Communications 13
(1): 6867.
11 November 2022
Cysteine engineering of polyproteins for single-molecule force spectroscopy.
Dietz, H., Bertz, M., Schlierf, M., Berkemeier, F., Bornschloegl, T., Junker, J.P. and Rief, M.
Nature Protocols 1
(1): 80-84.
2006
Ventricular remodeling after acute myocardial infarction.
Dietz, R., Osterziel, K.J., Willenbrock, R., Gulba, D.C. and von Harsdorf, R.
Thrombosis and Haemostasis 82
(Suppl 1): 73-75.
September 1999
Structure of the merozoite surface protein 1 from Plasmodium falciparum.
Dijkman, P.M., Marzluf, T., Zhang, Y., Chang, S.Y.S., Helm, D., Lanzer, M., Bujard, H. and Kudryashev, M.
Science Advances 7
(23): eabg0465.
June 2021
Comparison of R-CHOP-14 and R-mini-CHOP in older adults with diffuse large B-cell lymphoma - a retrospective multicenter cohort study.
Dilbaz, Z.G., Denker, S., Ankermann, C., Bittenbring, J.T., Kaddu-Mulindwa, D., Kunte, A.S., Hünecke, S., Poeschel, V., Stilgenbauer, S., Thurner, L., Na, I.K., Bewarder, M. and Christofyllakis, K.
European Journal of Haematology 113
(5): 675-684.
November 2024
COVID19-associated cardiomyocyte dysfunction, arrhythmias and the effect of Canakinumab.
Dimai, S., Semmler, L., Prabhu, A., Stachelscheid, H., Huettemeister, J., Klaucke, S.C., Lacour, P., Blaschke, F., Kruse, J., Parwani, A., Boldt, L.H., Bullinger, L., Pieske, B.M., Heinzel, F.R. and Hohendanner, F.
PLoS ONE 16
(8): e0255976.
19 August 2021
Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast.
Dimmer, K.S., Jakobs, S., Vogel, F., Altmann, K. and Westermann, B.
Journal of Cell Biology 168
(1): 103-115.
3 January 2005
Genome-wide search for miRNA-target interactions in Arabidopsis thaliana with an integrated approach.
Ding, J., Li, D., Ohler, U., Guan, J. and Zhou, S.
BMC Genomics 13
(Suppl 3): S3.
11 June 2012
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
Ding, Q., Xia, W., Liu, J.C., Yang, J.Y., Lee, D.F., Xia, J., Bartholomeusz, G., Li, Y., Pan, Y., Li, Z., Bargou, R.C., Qin, J., Lai, C.C., Tsai, F.J., Tsai, C.H. and Hung, M.C.
Molecular Cell 19
: 159-170.
1 January 2005
PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
Dittmar, G., Perez Hernandez, D., Kowenz-Leutz, E., Kirchner, M., Kahlert, G., Wesolowski, R., Baum, K., Knoblich, M., Hofstätter, M., Muller, A., Wolf, J., Reimer, U. and Leutz, A.
iScience 13
: 351-370.
29 March 2019
Molecular dynamics simulations of the 136 unique tetranucleotide sequences of DNA oligonucleotides. II. Sequence context effects on the dynamical structures of the 10 unique dinucleotide steps.
Dixit, S.B., Beveridge, D.L., Case, D.A., Cheatham, T.E., Guidice, E., Lankas, F., Lavery, R., Maddocks, J.H., Osman, R., Sklenar, H., Thayer, K. and Varnai, P.
Biophysical Journal 89
(6): 3721-3740.
December 2005
Clinical utility of a protein-based oncopanel in patients with end-stage head and neck cancer.
Doescher, J., Weissinger, S.E., Schönsteiner, S.S., Lisson, C., Bullinger, L., Barth, T.F., Leithäuser, F., Mueller-Richter, U., Laban, S., Hoffmann, T.K., Möller, P., Lennerz, J.K. and Schuler, P.J.
Immunotherapy 11
(14): 1193-1203.
October 2019
NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
Doffo, J., Bamopoulos, S.A., Köse, H., Orben, F., Zang, C., Pons, M., den Dekker, A.T., Brouwer, R.W.W., Baluapuri, A., Habringer, S., Reichert, M., Illendula, A., Krämer, O.H., Schick, M., Wolf, E., van IJcken, W.F.J., Esposito, I., Keller, U., Schneider, G. and Wirth, M.
Proceedings of the National Academy of Sciences of the United States of America 119
(9): e2105691119.
1 March 2022
Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient.
Doll, S., Kriegmair, M.C., Santos, A., Wierer, M., Coscia, F., Neil, H.M., Porubsky, S., Geyer, P.E., Mund, A., Nuhn, P. and Mann, M.
Molecular Oncology 12
(8): 1296-1307.
August 2018
Zukunfts-Szenarien: Szenario-Workshop mit Laien und Experten zu moeglichen Einfluessen der Wirtschaft auf die biomedizinische Forschung.
Domasch, S.
GenomXpress 3
: 18.
March 2003
Transparenz und Erfahrbarkeit von Wissen - Bioethik und Wissenschaftskommunikation.
Domasch, S. and Tannert, C.
Zeitschrift fuer Humanontogenetik 6
: 82-83.
1 January 2003
Retained functional normal and preleukemic HSCs at diagnosis are associated to good prognosis in DNMT3Amut NPM1mut AMLs.
Donato, E., Correia, N.C., Andresen, C., Karpova, D., Würth, R., Klein, C., Sohn, M., Przybylla, A., Zeisberger, P., Rothfelder, K., Salih, H.R., Bonig, H., Stasik, S., Röllig, C., Dolnik, A., Bullinger, L., Buchholz, F., Thiede, C.D., Hübschmann, D. and Trumpp, A.
Blood Advances 7
(6): 1011-1018.
28 March 2023
Loss of methylation at the IFNG promoter and CNS-1 associates with the development of functional IFN-γ memory in human CD4(+) T lymphocytes.
Dong, J., Chang, H.D., Ivascu, C., Qian, Y., Rezai, S., Okhrimenko, A., Cosmi, L., Maggi, L., Eckhardt, F., Wu, P., Sieper, J., Alexander, T., Annunziato, F., Gossen, M., Li, J., Radbruch, A. and Thiel, A.
European Journal of Immunology 43
(3): 793-804.
March 2013
N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness.
Dong, Hongliang, Zeng, Lili, Chen, Weiwei, Zhang, Qian, Wang, Fei, Wu, Yan, Cui, Bingjie, Qi, Jingjing, Zhang, Xin, Liu, Cuilan, Deng, Jiong, Yu, Y., Schmitt, C.A. and Du, Jing
Cell Death Discovery 9
(1): 149.
6 May 2023
Preimplantation development regulatory pathway construction through a text-mining approach.
Donnard, E., Barbosa-Silva, A., Guedes, R.L., Fernandes, G.R., Velloso, H., Kohn, M.J., Andrade-Navarro, M.A. and Ortega, J.M.
BMC Genomics 12
(Suppl 4): S3.
22 December 2011
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H., Pusch, F., Bei, Y., von Stebut, J., Ibáñez, G., Guillan, K., Imami, K., Gürgen, D., Rolff, J., Helmsauer, K., Meyer-Liesener, S., Timme, N., Bardinet, V., Chamorro González, R., MacArthur, I.C., Chen, C.Y., Schulz, J., Wengner, A.M., Furth, C., Lala, B., Eggert, A., Seifert, G., Hundsoerfer, P., Kirchner, M., Mertins, P., Selbach, M., Lissat, A., Dubois, F., Horst, D., Schulte, J.H., Spuler, S., You, D., Dela Cruz, F., Kung, A.L., Haase, K., Di Virgilio, M., Scheer, M., Ortiz, M.V. and Henssen, A.G.
Nature Communications 13
(1): 4297.
25 July 2022
Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M., Klinger, B., Mari, T., Toedling, J., Blanc, E., Messerschmidt, C., Nadler-Holly, M., Ziehm, M., Sieber, A., Hertwig, F., Beule, D., Eggert, A., Schulte, J.H., Selbach, M. and Blüthgen, N.
PLoS Computational Biology 17
(11): e1009515.
4 November 2021
MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.
Dorsett, Y., McBride, K.M., Jankovic, M., Gazumyan, A., Thai, T.H., Robbiani, D.F., Di Virgilio, M., Reina San-Martin, B., Heidkamp, G., Schwickert, T.A., Eisenreich, T., Rajewsky, K. and Nussenzweig, M.C.
Immunity 28
(5): 630-638.
16 May 2008
RP4 repressor protein KorB binds to the major groove of the operator DNA: A Raman study.
Dostal, L., Khare, D., Bok, J., Heinemann, U., Lanka, E. and Welfle, H.
Biochemistry 42
(49): 14476-14482.
1 January 2003
Raman spectroscopy of regulatory protein Omega from Streptococcus pyogenes plasmid pSM19035 and complexes with operator DNA.
Dostal, L., Misselwitz, R., Laettig, S., Alonso, J.C. and Welfle, H.
Spectroscopy 17
(2-3): 435-445.
2003
Binding of regulatory protein omega from Streptococcus pyogenes plasmid pSM19035 to direct and inverted 7-base pair repeats of operator DNA.
Dostal, L., Pratto, F., Alonso, J.C. and Welfle, H.
Journal of Raman Spectroscopy 38
(2): 166-175.
February 2007
Simultaneous imaging and flow-cytometry-based detection of multiple fluorescent senescence markers in therapy-induced senescent cancer cells.
Dovjak, E., Mairhofer, M., Wöß, C., Qi, J., Fan, D.N.Y., Schmitt, C.A. and Yu, Y.
Journal of Visualized Experiments
(185): e63973.
12 July 2022
Antitumor activity of Titanocene Y in xenografted PC3 tumors in mice.
Dowling, C.M., Claffey, J., Cuffe, S., Fichtner, I., Pampillon, C., Sweeney, N.J., Strohfeldt, K., Watson, R.W. and Tacke, M.
Letters in Drug Design & Discovery 5
(2): 141-144.
March 2008
From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic acid and db-cAMP in vitro differentiation model.
Drab, M., Haller, H., Bychkov, R., Erdmann, B., Lindschau, C., Haase, H., Morano, I., Luft, F.C. and Wobus, A.M.
FASEB Journal 11
(11): 905-915.
September 1997
CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
Drachsler, M., Kleber, S., Mateos, A., Volk, K., Mohr, N., Chen, S., Cirovic, B., Tuettenberg, J., Gieffers, C., Sykora, J., Wirtz, C.R., Mueller, W., Synowitz, M. and Martin-Villalba, A.
Cell Death & Disease 7
: e2209.
28 April 2016
T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3-bispecific single-chain antibody construct1.
Dreier, T., Baeuerle, P.A., Fichtner, I., Gruen, M., Schlereth, B., Lorenczewski, G., Kufer, P., Lutterbuese, R., Riethmueller, G., Gjorstrup, P. and Bargou, R.C.
Journal of Immunology 170
(8): 4397-4402.
15 April 2003
PET in colorectal cancer.
Dresel, S. and Schlag, P.M.
Recent Results in Cancer Research 170
: 109-124.
2008
Modeling Structure-Activity Relationship of AMPK Activation.
Drewe, J., Küsters, E., Hammann, F., Kreuter, M., Boss, P. and Schöning, V.
Molecules 26
(21): 6508.
1 November 2021
Deep learning for prediction of population health costs.
Drewe-Boss, P., Enders, D., Walker, J. and Ohler, U.
BMC Medical Informatics and Decision Making 22
(1): 32.
3 February 2022
omniCLIP: probabilistic identification of protein-RNA interactions from CLIP-seq data.
Drewe-Boss, P., Wessels, H.H. and Ohler, U.
Genome Biology 19
: 183.
1 November 2018
MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis.
Dreyling, M.H., Schrader, K., Fonatsch, C., Schlegelberger, B., Haase, D., Schoch, C., Ludwig, W.D., Loeffler, H., Buechner, T., Wormann, B., Hiddemann, W. and Bohlander, S.K.
Blood 91
(12): 4662-4667.
15 June 1998
HCMV-encoded chemokine receptor US28 employs multiple routes for internalization.
Droese, J., Mokros, T., Hermosilla, R., Schuelein, R., Lipp, M., Höpken, U.E. and Rehm, A.
Biochemical and Biophysical Research Communications 322
(1): 42-49.
10 September 2004
Orientation regulation of class-switch recombination in human B cells.
Du, L., Oksenych, V., Wan, H., Ye, X., Dong, J., Ye, A.Y., Abolhassani, H., Vlachiotis, S., Zhang, X., de la Rosa, K., Hammarström, L., van der Burg, M., Alt, F.W. and Pan-Hammarström, Q.
Journal of Immunology 213
(8): 1093-1104.
15 October 2024
Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J., Neuenschwander, M., Yu, Y., Däbritz, J.H.M., Neuendorff, N.R., Schleich, K., Bittner, A., Milanovic, M., Beuster, G., Radetzki, S., Specker, E., Reimann, M., Rosenbauer, F., Mathas, S., Lohneis, P., Hummel, M., Dörken, B., von Kries, J.P., Lee, S. and Schmitt, C.A.
Blood 129
(1): 71-81.
5 January 2017
Generation of Epstein-Barr virus antigen-specific T cell receptors recognizing immunodominant epitopes of LMP1, LMP2A, and EBNA3C for immunotherapy.
Dudaniec, K., Westendorf, K., Nössner, E. and Uckert, W.
Human Gene Therapy 32
(17-18): 919-935.
21 September 2021
Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomography.
Dudkina, N.V., Kudryashev, M., Stahlberg, H. and Boekema, E.J.
Proceedings of the National Academy of Sciences of the United States of America 108
(37): 15196-15200.
13 September 2011
Limited relevance of the CHEK2 gene in hereditary breast cancer.
Dufault, M.R., Betz, B., Wappenschmidt, B., Hofmann, W., Bandick, K., Golla, A., Pietschmann, A., Nestle-Kraemling, C., Rhiem, K., Huettner, C., von Lindern, C., Dall, P., Kiechle, M., Untch, M., Jonat, W., Meindl, A., Scherneck, S., Niederacher, D., Schmutzler, R.K. and Arnold, N.
International Journal of Cancer 110
(3): 320-325.
1 January 2004
Epigenomic profiling of human CD4(+) T cells supports a linear differentiation model and highlights molecular regulators of memory development.
Durek, P., Nordström, K., Gasparoni, G., Salhab, A., Kressler, C., de Almeida, M., Bassler, K., Ulas, T., Schmidt, F., Xiong, J., Glažar, P., Klironomos, F., Sinha, A., Kinkley, S., Yang, X., Arrigoni, L., Amirabad, A.., Ardakani, F.B., Feuerbach, L., Gorka, O., Ebert, P., Müller, F., Li, N., Frischbutter, S., Schlickeiser, S., Cendon, C., Fröhler, S., Felder, B., Gasparoni, N., Imbusch, C.D., Hutter, B., Zipprich, G., Tauchmann, Y., Reinke, S., Wassilew, G., Hoffmann, U., Richter, A.S., Sieverling, L., Chang, H.D., Syrbe, U., Kalus, U., Eils, J., Brors, B., Manke, T., Ruland, J., Lengauer, T., Rajewsky, N., Chen, W., Dong, J., Sawitzki, B., Chung, H.R., Rosenstiel, P., Schulz, M.H., Schultze, J.L., Radbruch, A., Walter, J., Hamann, A. and Polansky, J.K.
Immunity 45
(5): 1148-1161.
15 November 2016
Functional classification of TP53 mutations in acute myeloid leukemia.
Dutta, S., Pregartner, G., Rücker, F.G., Heitzer, E., Zebisch, A., Bullinger, L., Berghold, A., Döhner, K. and Sill, H.
Cancers 12
(3): 637.
10 March 2020
Human promoters are intrinsically directional.
Duttke, S.H.C., Lacadie, S.A., Ibrahim, M.M., Glass, C.K., Corcoran, D.L., Benner, C., Heinz, S., Kadonaga, J.T. and Ohler, U.
Molecular Cell 57
(4): 674-684.
19 February 2015
Evaluation of aggression and fearfulness in domestic dog (Canis familiaris).
Dyjak, M., Boruta, A., Adamkiewicz, E., Walasek, A., Bury-Burzymski, P. and Lisowski, P.
Animal Science Papers and Reports 39
(4): 407-418.
2021
Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin.
Dyring-Andersen, B., Løvendorf, M.B., Coscia, F., Santos, A., Møller, L.B.P., Colaço, A.R., Niu, L., Bzorek, M., Doll, S., Andersen, J.L., Clark, R.A., Skov, L., Teunissen, M.B.M. and Mann, M.
Nature Communications 11
(1): 5587.
5 November 2020
Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.
Dzamukova, M., Brunner, T.M., Miotla-Zarebska, J., Heinrich, F., Brylka, L., Mashreghi, M.F., Kusumbe, A., Kühn, R., Schinke, T., Vincent, T.L.. and Löhning, M.
Nature Communications 13
(1): 3059.
1 June 2022
CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma.
Däbritz, J.H.M., Yu, Y., Milanovic, M., Schönlein, M., Rosenfeldt, M.T., Dörr, J.R., Kaufmann, A.M., Dörken, B. and Schmitt, C.A.
Molecular Cancer Therapeutics 15
(5): 1074-1081.
May 2016
Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care.
Döhner, H., Dolnik, A., Tang, L., Seymour, J.F., Minden, M.D., Stone, R.M., Del Castillo, T.B., Al-Ali, H.K., Santini, V., Vyas, P., Beach, C L., MacBeth, K.J., Skikne, B.S., Songer, S., Tu, N., Bullinger, L. and Dombret, H.
Leukemia 32
(12): 2546-2557.
December 2018
Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Kühn, M.W.M., Schroeder, T., Mayer, K., Lübbert, M., Wattad, M., Götze, K., Fransecky, L., Koller, E., Wulf, G., Schleicher, J., Ringhoffer, M., Greil, R., Hertenstein, B., Krauter, J., Martens, U.M., Nachbaur, D., Samra, M.A., Machherndl-Spandl, S., Basara, N., Leis, C., Schrade, A., Kapp-Schwoerer, S., Cocciardi, S., Bullinger, L., Thol, F., Heuser, M., Paschka, P., Gaidzik, V.I., Saadati, M., Benner, A., Schlenk, R.F., Döhner, K. and Ganser, A.
Lancet Haematology 10
(7): e495-e509.
July 2023
Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Wulf, G.G., Salih, H.R., Lübbert, M., Kühn, M., Schroeder, T., Salwender, H., Götze, K.S., Westermann, J., Fransecky, L., Mayer, K., Hertenstein, B., Ringhoffer, M., Tischler, H.J., Machherndl-Spandl, S., Schrade, A., Paschka, P., Gaidzik, V.I., Theis, F., Thol, F.R., Heuser, M., Schlenk, R.F., Bullinger, L., Saadati, M., Benner, A., Larson, R.A., Stone, R.M., Döhner, K. and Ganser, A.
Blood Advances 6
(18): 5345-5355.
27 September 2022
Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Dönig, J., Mende, H., Davila Gallesio, J., Wagner, K., Hotz, P., Schunck, K., Piller, T., Hölper, S., Uhan, S., Kaulich, M., Wirth, M., Keller, U., Tascher, G., Bohnsack, K.E. and Müller, S.
Nature Communications 14
(1): 8121.
8 December 2023
Longtime outcome after intraosseous application of autologous mesenchymal stromal cells in pediatric patients and young adults with avascular necrosis after steroid or chemotherapy.
Döring, M., Kluba, T., Cabanillas Stanchi, K.M., Kahle, P., Lenglinger, K., Tsiflikas, I., Treuner, C., Vaegler, M., Mezger, M., Erbacher, A., Schumm, M., Lang, P., Handgretinger, R. and Müller, I.
Stem Cells and Development 29
(13): 811-822.
July 2020
Effective symptom relief through continuous integration of palliative care in advanced renal cell carcinoma patients: comprehensive measurement using the palliative care base assessment.
Dörr, A., Vogel, I., Wittenbecher, F., Westermann, J., Thuss-Patience, P., Ahn, J., Pelzer, U., Hardt, J., Bullinger, L. and Flörcken, A.
Palliative Care and Social Practice 18
: 26323524241260424.
24 June 2024
Thrombus or tumor? A case report of a rare sarcoma entity: intimal sarcoma of the pulmonary arteries.
Dörr, A., Flörcken, A, Bullinger, L., Capper, D., Von Deimling, A., Kaul, D., Märdian, S., Starck, C., Horst, D., Dragomir, M.P., Schäfer, F.M. and Jarosch, A.
Molecular Biology Reports 51
: 568.
24 April 2024
C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages.
Dörr, D., Obermayer, B., Weiner, J.M., Zimmermann, K., Anania, C., Wagner, L.K., Lyras, E.M., Sapozhnikova, V., Lara-Astiaso, D., Prósper, F., Lang, R., Lupiáñez, D.G., Beule, D., Höpken, U.E., Leutz, A. and Mildner, A.
Science Immunology 7
(75): eabj0140.
September 2022
Germline mutations including the rare pathogenic variant c.3206delC in the ATM gene cause ataxia teleangiectasia-associated primary central nervous system lymphoma.
Dörr, J.R., Thorwarth, A., Mizia-Malarz, A., Radke, J., Tietze, A., Hernáiz-Driever, P., Horn, D., Gratopp, A., Eggert, A. and Deubzer, H.E.
Children 8
(6): 469.
June 2021
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr, J.R., Yu, Y., Milanovic, M., Beuster, G., Zasada, C., Däbritz, J.H.M., Lisec, J., Lenze, D., Gerhardt, A., Schleicher, K., Kratzat, S., Purfürst, B., Walenta, S., Mueller-Klieser, W., Gräler, M., Hummel, M., Keller, U., Buck, A.K., Dörken, B., Willmitzer, L., Reimann, M., Kempa, S., Lee, S. and Schmitt, C.A.
Nature 501
(7467): 421-425.
19 September 2013
MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy.
Dössinger, G., Bunse, M., Bet, J., Albrecht, J., Paszkiewicz, P.J., Weißbrich, B., Schiedewitz, I., Henkel, L., Schiemann, M., Neuenhahn, M., Uckert, W. and Busch, D.H.
PLoS ONE 8
(4): e61384.
26 April 2013
Detection of Bombali virus in a Mops condylurus bat in Kyela, Tanzania.
Düx, A., Lwitiho, S.E., Ayouba, A., Röthemeier, C., Merkel, K., Weiss, S., Thaurignac, G., Lander, A., Kouadio, L., Nowak, K., Corman, V., Drosten, C., Couacy-Hymann, E., Krüger, D.H., Kurth, A., Calvignac-Spencer, S., Peeters, M., Ntinginya, N.E., Leendertz, F.H. and Mangu, C.
Viruses 16
(8): 1227.
August 2024
Quantitative imaging of gut microbiota spatial organization.
Earle, K.A., Billings, G., Sigal, M., Lichtman, J.S., Hansson, G.C., Elias, J.E., Amieva, M.R., Huang, K.C. and Sonnenburg, J.L.
Cell Host & Microbe 18
(4): 478-488.
14 October 2015
Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families.
Easton, D., Bishop, D.T., Ford, D., Crockford, G.P., Scherneck, S. and Zimmerman, W.
American Journal of Human Genetics 52
(4): 678-701.
April 1993
Spatial transcriptomics of C. elegans males and hermaphrodites identifies sex-specific differences in gene expression patterns.
Ebbing, A., Vértesy, Á., Betist, M.C., Spanjaard, B., Junker, J.P., Berezikov, E., van Oudenaarden, A. and Korswagen, H.C.
Developmental Cell 47
(6): 801-813.
17 December 2018
Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T(H)2-biased immunization.
Ebenig, A., Muraleedharan, S., Kazmierski, J., Todt, D., Auste, A., Anzaghe, M., Gömer, A., Postmus, D., Gogesch, P., Niles, M., Plesker, R., Miskey, C., Gellhorn Serra, M., Breithaupt, A., Hörner, C., Kruip, C., Ehmann, R., Ivics, Z., Waibler, Z., Pfaender, S., Wyler, E., Landthaler, M., Kupke, A., Nouailles, G., Goffinet, C., Brown, R.J.P and Mühlebach, M.D.
Cell Reports 40
(7): 111214.
16 August 2022
CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants.
Eberle, J., Fecker, L.F., Hossini, A.M., Wieder, T., Daniel, P.T., Orfanos, C.E. and Geilen, C.C.
Oncogene 22
(57): 9131-9141.
11 December 2003
Haplotype-resolved diverse human genomes and integrated analysis of structural variation.
Ebert, P., Audano, P. A., Zhu, Q., Rodriguez-Martin, B., Porubsky, D., Bonder, M.J., Sulovari, A., Ebler, J., Zhou, W., Serra Mari, R., Yilmaz, F., Zhao, X., Hsieh, P.H., Lee, J., Kumar, S., Lin, J., Rausch, T., Chen, Y., Ren, J., Santamarina, M., Höps, W., Ashraf, H., Chuang, N.T., Yang, X., Munson, K.M., Lewis, A.P., Fairley, S., Tallon, L.J., Clarke, W.E., Basile, A.O., Byrska-Bishop, M., Corvelo, A., Evani, U.S., Lu, T.Y., Chaisson, M.J.P., Chen, J., Li, C., Brand, H., Wenger, A.M., Ghareghani, M., Harvey, W.T., Raeder, B., Hasenfeld, P., Regier, A.A., Abel, H.J., Hall, I.M., Flicek, P., Stegle, O., Gerstein, M.B, Tubio, J.M.C., Mu, Z., Li, Y.I., Shi, X., Hastie, A.R., Ye, K., Chong, Z., Sanders, A.D., Zody, M.C., Talkowski, M.E., Mills, R. E., Devine, S.E., Lee, C., Korbel, J.O., Marschall, T. and Eichler, E.E.
Science 372
(6537): eabf7117.
25 February 2021
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Ebralidze, A.K., Guibal, F.C., Steidl, U., Zhang, P., Lee, S., Bartholdy, B., Jorda, M.A., Petkova, V., Rosenbauer, F., Huang, G., Dayaram, T., Klupp, J., O'Brien, K.B., Will, B., Hoogenkamp, M., Borden, K.L., Bonifer, C. and Tenen, D.G.
Genes & Development 22
(15): 2085-2092.
1 August 2008
Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes.
Ebstein, F., Textoris-Taube, K., Keller, C., Golnik, R., Vigneron, N., Van den Eynde, B.J., Schuler-Thurner, B., Schadendorf, D., Lorenz, F.K.M., Uckert, W., Urban, S., Lehmann, A., Albrecht-Koepke, N., Janek, K., Henklein, P., Niewienda, A., Kloetzel, P.M. and Mishto, M.
Scientific Reports 6
: 24032.
6 April 2016
Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L., Czajkowski, M.T., Barth, C., Müller, P.M., McShane, E., Grunwald, S., Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G., Selbach, M., Hammes, A., Daumke, O., Klussmann, E., Urbé, S. and Rocks, O.
Nature Communications 7
: 12963.
7 October 2016
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Ecker, J., Oehme, I., Mazitschek, R., Korshunov, A., Kool, M., Hielscher, T., Kiss, J., Selt, F., Konrad, C., Lodrini, M., Deubzer, H.E., von Deimling, A., Kulozik, A.E., Pfister, S.M., Witt, O. and Milde, T.
Acta Neuropathologica Communications 3
: 22.
3 April 2015
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts.
Eckert, M.A., Coscia, F., Chryplewicz, A., Chang, J.W., Hernandez, K.M., Pan, S., Tienda, S.M., Nahotko, D.A., Li, G., Blaženović, I., Lastra, R.R., Curtis, M., Yamada, S.D., Perets, R., McGregor, S.M., Andrade, J., Fiehn, O., Moellering, R.E., Mann, M. and Lengyel, E.
Nature 569
(7758): 723-728.
30 May 2019
Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Edelmann, J., Holzmann, K., Tausch, E., Saunderson, E.A., Jebaraj, B.M.C., Steinbrecher, D., Dolnik, A., Blätte, T.J., Landau, D.A., Saub, J., Estenfelder, S., Ibach, S., Cymbalista, F., Leblond, V., Delmer, A., Bahlo, J., Robrecht, S., Fischer, K., Goede, V., Bullinger, L., Wu, C.J., Mertens, D., Ficz, G., Gribben, J.G., Hallek, M., Döhner, H. and Stilgenbauer, S.
Haematologica 105
(5): 1379-1390.
May 2020
TCR and CAR engineering of primary human T cells.
Edes, I., Clauss, J., Stahn, R., Sada Japp, A. and Lorenz, F.K.M.
Methods in Molecular Biology 2521
(3): 85-93.
23 June 2022
Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma.
Edginton-White, B., Cauchy, P., Assi, S.A., Hartmann, S., Riggs, A.G., Mathas, S., Cockerill, P.N. and Bonifer, C.
Leukemia 33
(6): 1463-1474.
June 2019
Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial.
Eich, H.T., Diehl, V., Goergens, H., Pabst, T., Markova, J., Debus, J., Ho, A., Doerken, B., Rank, A., Grosu, A.L., Wiegel, T., Karstens, J.H., Greil, R., Willich, N., Schmidberger, H., Doehner, H., Borchmann, P., Mueller-Hermelink, H.K., Mueller, R.P. and Engert, A.
Journal of Clinical Oncology 28
(27): 4199-4206.
20 September 2010
Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
Eichenauer, D.A., Plütschow, A., Kreissl, S., Sökler, M., Hellmuth, J.C., Meissner, J., Mathas, S., Topp, M.S., Behringer, K., Klapper, W., Kuhnert, G., Dietlein, M., Kobe, C., Fuchs, M., Diehl, V., Engert, A. and Borchmann, P.
Lancet Oncology 18
(12): 1680-1687.
December 2017
Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL - long-term follow-up from the prospective ALL-SCT 2003 trial.
Eichinger, A., Poetschger, U., Glogova, E., Bader, P., Basu, O., Beier, R., Burkhardt, B., Classen, C.F., Claviez, A., Corbacioglu, S., Deubzer, H.E., Greil, J., Gruhn, B., Güngör, T., Kafa, K., Kühl, J.S., Lang, P., Lange, B.S., Meisel, R., Müller, I., Sauer, M.G., Schlegel, P.G., Schulz, A., Stachel, D., Strahm, B., Wawer, A., Peters, C. and Albert, M.H.
Leukemia 36
(11): 2567-2576.
November 2022
In colon epithelia, Clostridium perfringens enterotoxin causes focal leaks by targeting claudins which are apically accessible due to tight junction derangement.
Eichner, M., Augustin, C., Fromm, A., Piontek, A., Walther, W., Buecker, R., Fromm, M., Krause, G., Schulzke, J.D., Guenzel, D. and Piontek, J.
Journal of Infectious Diseases 217
(1): 147-157.
27 December 2017
Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert, T., Hsu, C.J., Becker, A.L., Graessle, S., Horne, A., Bemmann, F., Zhang, Q., Heuser, M., Vasioukhin, V., Scholl, S., Hochhaus, A., Siegerist, F., Endlich, N., Bullinger, L., Lane, S.W., Haas, S., Schnoeder, T.M and Heidel, F.H.
Leukemia 37
(10): 2027-2035.
October 2023
ASHLEYS: automated quality control for single-cell Strand-seq data.
Eimer, C., Sanders, A.D., Korbel, J.O., Marschall, T. and Ebert, P.
Bioinformatics 37
(19): 3356-3357.
1 October 2021
Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak and augments drug response.
Einsele-Scholz, S., Malmsheimer, S., Bertram, K., Stehle, D., Johaenning, J., Manz, M., Daniel, P.T., Gillissen, B.F., Schulze-Osthoff, K. and Essmann, F.
Journal of Cell Science 129
(11): 2213-2223.
1 June 2016
Histone deacetylase inhibitors have antitumor activity in two NOD/SCID mouse models of B-cell precursor childhood acute lymphoblastic leukemia.
Einsiedel, H.G., Kawan, L., Eckert, C., Witt, O., Fichtner, I., Henze, G. and Seeger, K.
Leukemia 20
(8): 1435-1436.
August 2006
Hepatoprotection in bile duct ligated mice mediated by darbepoetin-α is not caused by changes in hepatobiliary transporter expression.
Eipel, C., Menschikow, E., Sigal, M., Kuhla, A., Abshagen, K. and Vollmar, B.
International Journal of Clinical and Experimental Pathology 6
(1): 80-90.
1 January 2013
13C isotopologue perturbation studies of Listeria monocytogenes carbon metabolism and its modulation by the virulence regulator PrfA.
Eisenreich, W., Slaghuis, J., Laupitz, R., Bussemer, J., Stritzker, J., Schwarz, C., Schwarz, R., Dandekar, T., Goebel, W. and Bacher, A.
Proceedings of the National Academy of Sciences of the United States of America 103
(7): 2040-2045.
14 February 2006
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation.
Eitler, J., Rackwitz, W., Wotschel, N., Gudipati, V., Murali Shankar, N., Sidorenkova, A., Huppa, J.B., Ortiz-Montero, P., Opitz, C., Künzel, S.R., Michen, S., Temme, A., Loureiro, L.R., Feldmann, A., Bachmann, M., Boissel, L., Klingemann, H., Wels, W.S. and Tonn, T.
Journal for ImmunoTherapy of Cancer 12
(2): e008155.
27 February 2024
Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells.
Ekland, E.H., Forster, R., Lipp, M. and Cyster, J.G.
Journal of Immunology 172
(8): 4700-4708.
15 April 2004
The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
El-Athman, R., Genov, N.N., Mazuch, J., Zhang, K., Yu, Y., Fuhr, L., Abreu, M., Li, Y., Wallach, T., Kramer, A., Schmitt, C.A. and Relógio, A.
PLoS Biology 15
(12): e2002940.
7 December 2017
12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells.
El-Shemerly, M.Y., Besser, D., Nagasawa, M. and Nagamine, Y.
Journal of Biological Chemistry 272
(49): 30599-30602.
5 December 1997
Sugar metabolism of the first thermophilic planctomycete thermogutta terrifontis: comparative genomic and transcriptomic approaches.
Elcheninov, A.G., Menzel, P., Gudbergsdottir, S.R., Slesarev, A.I., Kadnikov, V.V., Krogh, A., Bonch-Osmolovskaya, E.A., Peng, X. and Kublanov, I.V.
Frontiers in Microbiology 8
: 2140.
2 November 2017
Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinases-1 in the liver: efficient protection against T-cell lymphoma and colon carcinoma metastasis.
Elezkurtaj, S., Kopitz, C., Baker, A.H., Perez-Canto, A., Arlt, M.J., Khokha, R., Gansbacher, B., Anton, M., Brand, K. and Krueger, A.
Journal of Gene Medicine 6
(11): 1228-1237.
23 September 2004
IkappaBalpha is required for marginal zone B cell lineage development.
Ellinghaus, U., Rupec, R.A., Pabst, O., Ignatius, R., Foerster, R., Doerken, B. and Jundt, F.
European Journal of Immunology 38
(8): 2096-2105.
August 2008
An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils.
Ellson, C.D., Goretti Riça, I., Kim, J.S., Huang, Y.M.M., Lim, D., Mitra, T., Hsu, A., Wei, E.X., Barrett, C.D., Otterbein, L.E., Hauser, C.J., Wahl, M., Delbrück, H., Heinemann, U., Oschkinat, H., Chang, C.E.A. and Yaffe, M.B.
Journal of Molecular Biology 434
(9): 167533.
15 May 2022
Mobile phones and health: Media coverage study of German newspapers on possible adverse health effects of mobile phone use.
Elvers, H.D., Jandrig, B., Grummich, K. and Tannert, C.
Health, Risk & Society 11
(2): 165-179.
April 2009
Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells.
Emmerich, F., Theurich, S., Hummel, M., Haeffker, A., Vry, M.S., Doehner, K., Bommert, K., Stein, H. and Doerken, B.
Journal of Pathology 201
(3): 413-420.
November 2003
Detection of tumor-specific mRNA in cell-free bronchial lavage supernatant in patients with lung cancer.
Engel, E., Schmidt, B., Carstensen, T., Weickmann, S., Jandrig, B., Witt, C. and Fleischhacker, M.
Annals of the New York Academy of Sciences 1022
: 140-146.
1 June 2004
Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif.
Engel, K., Schultz, H., Martin, F., Kotlyarov, A., Plath, K., Hahn, M., Heinemann, U. and Gaestel, M.
Journal of Biological Chemistry 270
(45): 27213-27221.
10 November 1995
Structural domains required for channel function of the mouse transient receptor potential protein homologue TRP1beta.
Engelke, M., Friedrich, O., Budde, P., Schaefer, C., Niemann, U., Zitt, C., Juengling, E., Rocks, O., Lueckhoff, A. and Frey, J.
FEBS Letters 523
(1-3): 193-199.
17 July 2002
Unsupervised meta-analysis on diverse gene expression datasets allows insight into gene function and regulation.
Engelmann, J.C., Schwarz, R., Blenk, S., Friedrich, T., Seibel, P.N., Dandekar, T. and Mueller, T.
Bioinformatics and Biology Insights 2
: 265-280.
26 May 2008
Retroviral vectors for high-level transgene expression in T lymphocytes.
Engels, B., Cam, H., Schueler, T., Indraccolo, S., Gladow, M., Baum, C., Blankenstein, T. and Uckert, W.
Human Gene Therapy 14
(12): 1155-1168.
10 August 2003
Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes.
Engels, B., Noessner, E., Frankenberger, B., Blankenstein, T., Schendel, D.J. and Uckert, W.
Human Gene Therapy 16
(7): 799-810.
1 July 2005
The Golgi protein RCAS1 controls cell surface expression of tumor-associated O-linked glycan antigens.
Engelsberg, A., Hermosilla, R., Karsten, U., Schuelein, R., Doerken, B. and Rehm, A.
Journal of Biological Chemistry 278
(25): 22998-23007.
1 January 2003
The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Doehner, H., Duyvene' de Wit, T., Eichinger, S., Fibbe, W., Green, T., de Haas, F., Iolascon, A., Jaffredo, T., Rodeghiero, F., Salles, G. and Schuringa, J.J.
Haematologica 101
(2): 115-208.
February 2016
Escalated-dose BEACOPP in the treatment of patients with advanced-stage Hodgkin's lymphoma: 10 years of follow-up of the GHSG HD9 study.
Engert, A., Diehl, V., Franklin, J., Lohri, A., Doerken, B., Ludwig, W.D., Koch, P., Haenel, M., Pfreundschuh, M., Wilhelm, M., Truemper, L., Aulitzky, W.E., Bentz, M., Rummel, M., Sezer, O., Mueller-Hermelink, H.K., Hasenclever, D. and Loeffler, M.
Journal of Clinical Oncology 27
(27): 4548-4554.
20 September 2009
Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.
Engert, A., Haverkamp, H., Kobe, C., Markova, J., Renner, C., Ho, A., Zijlstra, J., Kral, Z., Fuchs, M., Hallek, M., Kanz, L., Doehner, H., Doerken, B., Engel, N., Topp, M., Klutmann, S., Amthauer, H., Bockisch, A., Kluge, R., Kratochwil, C., Schober, O., Greil, R., Andreesen, R., Kneba, M., Pfreundschuh, M., Stein, H., Eich, H.T., Mueller, R.P., Dietlein, M., Borchmann, P. and Diehl, V.
Lancet 379
(9828): 1791-1799.
12 May 2012
Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.
Engert, A., Pluetschow, A., Eich, H.T., Lohri, A., Doerken, B., Borchmann, P., Berger, B., Greil, R., Willborn, K.C., Wilhelm, M., Debus, J., Eble, M.J., Soekler, M., Ho, A., Rank, A., Ganser, A., Truemper, L., Bokemeyer, C., Kirchner, H., Schubert, J., Kral, Z., Fuchs, M., Mueller-Hermelink, H.K., Mueller, R.P. and Diehl, V.
New England Journal of Medicine 363
(7): 640-652.
12 August 2010
Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.
Englbrecht, C.C., Schoof, H. and Boehm, S.
BMC Genomics 5
(1): 39.
5 July 2004
CS-1, a novel c-kithi+ acute myeloid leukemia cell line with dendritic cell differentiation capacity and absent immunogenicity.
Erben, U., Thiel, E., Bittroff-Leben, A., Schoch, C., Fichtner, I., Durkop, H. and Notter, M.
International Journal of Cancer 105
(2): 232-240.
10 June 2003
MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer.
Erdem, M., Lee, K.H., Hardt, M., Regan, J.L., Kobelt, D., Walther, W., Mokrizkij, M., Regenbrecht, C. and Stein, U.
Cancers 16
(3): 604.
31 January 2024
Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.
Erdmann, S., Senkel, S., Arndt, T., Lucas, B., Lausen, J., Klein-Hitpass, L., Ryffel, G.U. and Thomas, H.
Biological Chemistry 388
(1): 91-106.
January 2007
Parallel in-depth analysis of repeat expansions in ataxia patients by long-read sequencing.
Erdmann, H., Schöberl, F., Giurgiu, M., Leal Silva, R.M., Scholz, V., Scharf, F., Wendlandt, M., Kleinle, S., Deschauer, M., Nübling, G., Heide, W., Babacan, S.S., Schneider, C., Neuhann, T., Hahn, K., Schoser, B., Holinski-Feder, E., Wolf, D.A. and Abicht, A.
Brain 146
(5): 1831-1843.
May 2023
Efficient generation of B lymphocytes by recognition of self-antigens.
Eschbach, C., Bach, M.P., Fidler, I., Pelanda, R., Köhler, F., Rajewsky, K. and Jumaa, H.
European Journal of Immunology 41
(8): 2397-2403.
August 2011
Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy.
Escobar, H., Di Francescantonio, S., Smirnova, J., Graf, R., Müthel, S., Marg, A., Zhogov, A., Krishna, S., Metzler, E., Petkova, M., Daumke, O., Kühn, R. and Spuler, S.
Nature Communications 16
(1): 120.
2 January 2025
Base editing repairs an SGCA mutation in human primary muscle stem cells.
Escobar, H., Krause, A., Keiper, S., Kieshauer, J., Müthel, S., García de Paredes, M., Metzler, E., Kühn, R., Heyd, F. and Spuler, S.
JCI Insight 6
(10): e145994.
24 May 2021
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19.
Essex, M., Millet Pascual-Leone, B.L., Löber, U., Kuhring, M., Zhang, B., Brüning, U., Fritsche-Guenther, R., Krzanowski, M., Fiocca Vernengo, F., Brumhard, S., Röwekamp, I., Bielecka, A.A., Lesker, T.R., Wyler, E., Landthaler, M., Mantei, A., Meisel, C., Caesar, S., Thibeault, C., Corman, V.M., Marko, L., Suttorp, N., Strowig, T., Kurth, F., Sander, L.E., Li, Y., Kirwan, J.A., Forslund, S.K. and Opitz, B.
NPJ Biofilms and Microbiomes 10
(1): 66.
1 August 2024
Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis.
Essmann, F., Pohlmann, S., Gillissen, B., Daniel, P.T., Schulze-Osthoff, K. and Jaenicke, R.U.
Journal of Biological Chemistry 280
(44): 37169-37177.
4 November 2005
Stable conditional expression and effect of C/EBPβ-LIP in adipocytes using the pSLIK system.
Esteves, C.L., Kelly, V., Bégay, V., Lillico, S.G., Leutz, A., Seckl, J.R. and Chapman, K.
Journal of Molecular Endocrinology 51
(1): 91-98.
4 June 2013
Regulation of adipocyte 11beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) by CCAAT/enhancer-binding protein (C/EBP) beta isoforms, LIP and LAP.
Esteves, C.L., Kelly, V., Bégay, V., Man, T.Y., Morton, N.M., Leutz, A., Seckl, J.R. and Chapman, K.E.
PLoS ONE 7
(5): e37953.
25 May 2012
A balance between secreted inhibitors and edge sensing controls gastruloid self-organization.
Etoc, F., Metzger, J., Ruzo, A., Kirst, C., Yoney, A., Ozair, M.Z., Brivanlou, A.H. and Siggia, E.D.
Developmental Cell 39
(3): 302-315.
7 November 2016
Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information.
Ettrich, T.J., Schwerdel, D., Dolnik, A., Beuter, F., Blätte, T.J., Schmidt, S.A., Stanescu-Siegmund, N., Steinacker, J., Marienfeld, R., Kleger, A., Bullinger, L., Seufferlein, T. and Berger, A.W.
Scientific Reports 9
(1): 13261.
13 September 2019
Non-equilibrium steady states of stochastic processes with intermittent resetting.
Eule, S. and Metzger, J.J.
New Journal of Physics 18
(3): 033006.
March 2016
Predictors of lower exercise capacity in patients with cancer.
Evertz, R., Diehl, C., Gödde, K., Valentova, M., Garfias-Veitl, T., Overbeck, T.R., Braulke, F., Lena, A., Hadzibegovic, S., Bleckmann, A., Keller, U., Landmesser, U., König, A.O., Hasenfuss, G., Schuster, A., Anker, M.S. and von Haehling, S.
Scientific Reports 13
(1): 14861.
8 September 2023
Cardiovascular and metabolic determinants of quality of life in patients with cancer.
Evertz, R., Gödde, K., Diehl, C., Valentova, M., Garfias-Veitl, T., Braulke, F., Wulf, G.G., Overbeck, T.R., Bleckmann, A., König, A.O., Weinländer, P., Potthoff, S., Hadzibegovic, S., Lena, A., Keller, U., Landmesser, U., Schuster, A., Anker, M.S., Hasenfuß, G. and von Haehling, S.
ESC Heart Failure 10
(1): 167-176.
February 2023
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Exner, N., Treske, B., Paquet, D., Holmstroem, K., Schiesling, C., Gispert, S., Carballo-Carbajal, I., Berg, D., Hoepken, H.H., Gasser, T., Krueger, R., Winklhofer, K.F., Vogel, F., Reichert, A.S., Auburger, G., Kahle, P.J., Schmid, B. and Haass, C.
Journal of Neuroscience 27
(45): 12413-12418.
7 November 2007
Evidence for recombinant GRP78, CALR, PDIA3 and GPI as mediators of genetic instability in human CD34+ cells.
Fabarius, A., Samra, V., Drews, O., Mörz, H., Bierbaum, M., Darwich, A., Weiss, C., Brendel, S., Kleiner, H., Seifarth, W., Greffrath, W., Hofmann, W.K., Schmitt, C.A. and Popp, H.D.
Cancers 14
(12): 2883.
11 June 2022
CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.
Faber, K., Bullinger, L., Ragu, C., Garding, A., Mertens, D., Miller, C., Martin, D., Walcher, D., Döhner, K., Döhner, H., Claus, R., Plass, C., Sykes, S.M., Lane, S.W., Scholl, C. and Fröhling, S.
Journal of Clinical Investigation 123
(1): 299-314.
2 January 2013
The genomic landscape of core-binding factor acute myeloid leukemias.
Faber, Z.J., Chen, X., Gedman, A.L., Boggs, K., Cheng, J., Ma, J., Radtke, I., Chao, J.R., Walsh, M.P., Song, G., Andersson, A.K., Dang, J., Dong, L., Liu, Y., Huether, R., Cai, Z., Mulder, H., Wu, G., Edmonson, M., Rusch, M., Qu, C., Li, Y., Vadodaria, B., Wang, J., Hedlund, E., Cao, X., Yergeau, D., Nakitandwe, J., Pounds, S.B., Shurtleff, S., Fulton, R.S., Fulton, L.L., Easton, J., Parganas, E., Pui, C.H., Rubnitz, J.E., Ding, L., Mardis, E.R., Wilson, R.K., Gruber, T.A., Mullighan, C.G., Schlenk, R.F., Paschka, P., Döhner, K., Döhner, H., Bullinger, L., Zhang, J., Klco, J.M. and Downing, J.R.
Nature Genetics 48
(12): 1551-1556.
December 2016
Conformation of d (GGGATCCC) 2 in crystals and in solution studied by X-ray diffraction, Raman spectroscopy and molecular modelling.
Fabian, H., Hoelzer, W., Heinemann, U., Sklenar, H. and Welfle, H.
Nucleic Acids Research 21
(3): 569-576.
11 February 1993
GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.
Fabian, J., Lodrini, M., Oehme, I., Schier, M.C., Thole, T.M., Hielscher, T., Kopp-Schneider, A., Opitz, L., Capper, D., von Deimling, A., Wiegand, I., Milde, T., Mahlknecht, U., Westermann, F., Popanda, O., Roels, F., Hero, B., Berthold, F., Fischer, M., Kulozik, A.E., Witt, O. and Deubzer, H.E.
Cancer Research 74
(9): 2604-2616.
1 May 2014
MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Fabian, J., Opitz, D., Althoff, K., Lodrini, M., Hero, B., Volland, R., Beckers, A., de Preter, K., Decock, A., Patil, N., Abba, M., Kopp-Schneider, A., Astrahantseff, K., Wünschel, J., Pfeil, S., Ercu, M., Künkele, A., Hu, J., Thole, T., Schweizer, L., Mechtersheimer, G., Carter, D., Cheung, B.B., Popanda, O., von Deimling, A., Koster, J., Versteeg, R., Schwab, M., Marshall, G.M., Speleman, F., Erb, U., Zoeller, M., Allgayer, H., Simon, T., Fischer, M., Kulozik, A.E., Eggert, A., Witt, O., Schulte, J.H. and Deubzer, H.E.
Oncotarget 7
(41): 66344-66359.
11 October 2016
Crystal structure of nucleotide-free dynamin.
Faelber, K., Posor, Y., Gao, S., Held, M., Roske, Y., Schulze, D., Haucke, V., Noe, F. and Daumke, O.
Nature 477
(7366): 556-560.
29 September 2011
Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Faelber, K., Dietrich, L., Noel, J.K., Wollweber, F., Pfitzner, A.K., Mühleip, A., Sánchez, R., Kudryashev, M., Chiaruttini, N., Lilie, H., Schlegel, J., Rosenbaum, E., Hessenberger, M., Matthaeus, C., Kunz, S., von der Malsburg, A., Noé, F., Roux, A., van der Laan, M., Kühlbrandt, W. and Daumke, O.
Nature 571
(7765): 429-433.
18 July 2019
Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli, U.M., Ullrich, K., Stuehmer, T., Holien, T., Koechert, K., Holt, R.U., Bruland, O., Chatterjee, M., Nogai, H., Lenz, G., Shaughnessy, J.D., Mathas, S., Sundan, A., Bargou, R.C., Doerken, B., Borset, M. and Janz, M.
Oncogene 30
(28): 3198-3206.
14 July 2011
IL-33 expression is lower in current smokers at both transcriptomic and protein level.
Faiz, A., Mahbub, R.M., Boedijono, F.S., Tomassen, M.I., Kooistra, W., Timens, W., Nawijn, M., Hansbro, P.M., Johansen, M.D., Pouwels, S.D., Heijink, I.H., Massip, F., de Biase, M.S., Schwarz, R.F., Adcock, I.M., Chung, K.F., van der Does, A., Hiemstra, P.S., Goulaouic, H., Xing, H., Abdulai, R., de Rinaldis, E., Cunoosamy, D., Harel, S., Lederer, D., Nivens, M.C., Wark, P.A., Kerstjens, H.A.M., Hylkema, M.N., Brandsma, C.A. and van den Berge, M.
American Journal of Respiratory and Critical Care Medicine 208
(10): 1075-1087.
15 November 2023
DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution.
Falconer, E., Hills, M., Naumann, U., Poon, S.S.S., Chavez, E.A., Sanders, A.D., Zhao, Y., Hirst, M. and Lansdorp, P.M.
Nature Methods 9
(11): 1107-1112.
November 2012
Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: enhanced in vivo potency of encephalitogenic peptides.
Falk, K., Roetzschke, O., Santambrogio, L., Dorf, M.E., Brosnan, C. and Strominger, J.L.
Journal of Experimental Medicine 191
(4): 717-730.
21 February 2000
Pillars article: allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991. 351: 290-296.
Falk, K., Roetzschke, O., Stevanovic, S., Jung, G. and Rammensee, H.G.
Journal of Immunology 177
(5): 2741-2747.
1 September 2006
Genotoxic stress-induced senescence.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1896
: 93-105.
2019
Detecting markers of therapy-induced senescence in cancer cells.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1534
: 41-52.
2017
Age attenuates the T-type Ca(V) 3.2-RyR axis in vascular smooth muscle.
Fan, G., Kaßmann, M., Cui, Y., Matthaeus, C., Kunz, S., Zhong, C., Zhu, S., Xie, Yu, Tsvetkov, D., Daumke, O., Huang, Yu and Gollasch, M.
Aging Cell 19
(4): e13134.
April 2020
A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit via FRET in a binary system.
Fang, G.M., Chamiolo, J., Kankowski, S., Hövelmann, F., Friedrich, D., Löwer, A., Meier, J.C. and Seitz, O.
Chemical Science 9
(21): 4794-4800.
7 June 2018
A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis.
Fang, L., Zhu, Q., Neuenschwander, M., Specker, E., Wulf-Goldenberg, A., Weis, W.I., von Kries, J.P. and Birchmeier, W.
Cancer Research 76
(4): 891-901.
15 February 2016
Beta-catenin regulates P-cadherin expression in mammary basal epithelial cells.
Faraldo, M.M., Teuliere, J., Deugnier, M.A., Birchmeier, W., Huelsken, J., Thiery, J.P., Cano, A. and Glukhova, M.A.
FEBS Letters 581
(5): 831-836.
6 March 2007
Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets.
Farazi, T.A., Leonhardt, C.S., Mukherjee, N., Mihailovic, A., Li, S., Max, K.E.A., Meyer, C., Yamaji, M., Cekan, P., Jacobs, N.C., Gerstberger, S., Bognanni, C., Larsson, E., Ohler, U. and Tuschl, T.
RNA 20
(7): 1090-1102.
July 2014
Immunological memory: lessons from the past and a look to the future.
Farber, D.L., Netea, M.G., Radbruch, A., Rajewsky, K. and Zinkernagel, R.M.
Nature Reviews Immunology 16
(2): 124-128.
February 2016
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
Fasciani, I., Petragnano, F., Wang, Z., Edwards, R., Telugu, N., Pietrantoni, I., Zabel, U., Zauber, H., Grieben, M., Terzenidou, M.E., Di Gregorio, J., Pellegrini, C., Santini, S., Taddei, A.R., Pohl, B., Aringhieri, S., Carli, M., Aloisi, G., Marampon, F., Charlesworth, E., Roman, A., Diecke, S., Flati, V., Giorgi, F., Amicarelli, F., Tobin, A.B., Scarselli, M., Tokatlidis, K., Rossi, M., Lohse, M.J., Annibale, P. and Maggio, R.
PLoS Biology 22
(4): e3002582.
29 April 2024
Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination.
Fazal, S.V., Gomez-Sanchez, J.A., Wagstaff, L.J., Musner, N., Otto, G., Janz, M., Mirsky, R. and Jessen, K.R.
Journal of Neuroscience 37
(50): 12297-12313.
13 December 2017
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Fecher, C., Trovò, L., Müller, S.A., Snaidero, N., Wettmarshausen, J., Heink, S., Ortiz, O., Wagner, I., Kühn, R., Hartmann, J., Karl, R.M., Konnerth, A., Korn, T., Wurst, W., Merkler, D., Lichtenthaler, S.F., Perocchi, F. and Misgeld, T.
Nature Neuroscience 22
(10): 1731-1742.
October 2019
Loss of proapoptotic Bcl-2-related multidomain proteins in primary melanomas is associated with poor prognosis.
Fecker, L.F., Geilen, C.C., Tchernev, G., Trefzer, U., Assaf, C., Kurbanov, B.M., Schwarz, C., Daniel, P.T. and Eberle, J.
Journal of Investigative Dermatology 126
: 1366-1371.
June 2006
Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma.
Fehlker, M., Huska, M.R., Joens, T., Andrade-Navarro, M.A. and Kemmner, W.
BMC Cancer 14
(1): 64.
5 February 2014
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation.
Feinberg, M.W., Wara, A.K., Cao, Z., Lebedeva, M.A., Rosenbauer, F., Iwasaki, H., Hirai, H., Katz, J.P., Haspel, R., Gray, S., Akashi, K., Segre, J., Kaestner, K.H., Tenen, D.G. and Jain, M.K.
EMBO Journal 26
(18): 4138-4148.
19 September 2007
Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients.
Feldheim, J., Kessler, A.F., Schmitt, D., Wilczek, L., Linsenmann, T., Dahlmann, M., Monoranu, C.M., Ernestus, R.I., Hagemann, C. and Löhr, M.
OncoTargets and Therapy 11
: 8673-8684.
4 December 2018
Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients.
Fendler, A., Bauer, D., Busch, J., Jung, K., Wulf-Goldenberg, A., Kunz, S., Song, K., Myszczyszyn, A., Elezkurtaj, S., Erguen, B., Jung, S., Chen, W. and Birchmeier, W.
Nature Communications 11
(1): 929.
17 February 2020
Impact of individualized treatment on recovery from fatigue and return to work in survivors of advanced stage Hodgkin Lymphoma: results from the randomized international GHSG HD18 trial.
Ferdinandus, J., Müller, H., Damaschin, C., Jacob, A.S., Meissner, J., Krasniqi, F., Mey, U., Schöndube, D., Thiemer, J., Mathas, S., Zijlstra, J., Greil, R., Feuring-Buske, M., Markova, J., Rüffer, J.U., Kobe, C., Eich, H.T., Baues, C., Fuchs, M., Borchmann, P. and Behringer, K.
Annals of Oncology 35
(3): 276-284.
March 2024
Assessing evolutionary and developmental transcriptome dynamics in homologous cell types.
Feregrino, C. and Tschopp, P.
Developmental Dynamics 251
(9): 1472-1489.
September 2022
SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.
Fernández-Sáiz, V., Targosz, B.S., Lemeer, S., Eichner, R., Langer, C., Bullinger, L., Reiter, C., Slotta-Huspenina, J., Schroeder, S., Knorn, A.M., Kurutz, J., Peschel, C., Pagano, M., Kuster, B. and Bassermann, F.
Nature Cell Biology 15
(1): 72-81.
January 2013
SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin.
Ferone, G., Song, J.Y., Sutherland, K.D., Bhaskaran, R., Monkhorst, K., Lambooij, J.P., Proost, N., Gargiulo, G. and Berns, A.
Cancer Cell 30
(4): 519-532.
10 October 2016
Long-term efficacy, safety and neurotolerability of MATRix regimen followed by autologous transplant in primary CNS lymphoma: 7-year results of the IELSG32 randomized trial.
Ferreri, A.J.M., Cwynarski, K., Pulczynski, E., Fox, C.P., Schorb, E., Celico, C., Falautano, M., Nonis, A., La Rosée, P., Binder, M., Fabbri, A., Ilariucci, F., Krampera, M., Roth, Al., Hemmaway, C., Johnson, P.W., Linton, K.M., Pukrop, T., Gørløv, J.S., Balzarotti, M., Hess, G., Keller, U., Stilgenbauer, S., Panse, J., Tucci, A., Orsucci, L., Pisani, F., Zanni, M., Krause, S.W., Schmoll, H.J., Hertenstein, B., Rummel, M., Smith, J., Thurner, L., Cabras, G., Pennese, E., Ponzoni, M., Deckert, M., Politi, L.S., Finke, J., Ferranti, A., Cozens, K., Burger, E., Ielmini, N., Cavalli, F., Zucca, E. and Illerhaus, G.
Leukemia 36
(7): 1870-1878.
July 2022
Thioester and oxyester linkages in the ubiquitin system.
Ferri-Blazquez, A., Jarosch, E. and Sommer, T.
Methods in Molecular Biology 2602
: 3-18.
2023
In vivo identification of lymphocyte subsets exhibiting transcriptionally active NF-kappaB/Rel complexes.
Feuillard, J., Memet, S., Goudeau, B., Lilienbaum, A., Schmidt-Ullrich, R., Raphael, M. and Israel, A.
International Immunology 12
(5): 613-621.
May 2000
Haploinsufficiency of ETV6 and CDKN1B in patients with acute myeloid leukemia and complex karyotype.
Feurstein, S., Rücker, F.G., Bullinger, L., Hofmann, W., Manukjan, G., Göhring, G., Lehmann, U., Heuser, M., Ganser, A., Döhner, K., Schlegelberger, B. and Steinemann, D.
BMC Genomics 15
: 784.
11 September 2014
Telemedizinische Visionen.
Feussner, H., Ricke, J., Hufnagl, P. and Schlag, P.M.
Onkologe 9
(1): 48-51.
January 2003
Praeklinische Daten als Grundlage fuer die Konzeption klinischer Studien [Preclinical data as basis for the design of clinical studies].
Fichtner, I.
Onkologie 31
(Suppl. 2): 34-38.
May 2008
Antileukaemic activity of treosulfan in xenografted human acute lymphoblastic leukaemias (ALL).
Fichtner, I., Becker, M. and Baumgart, J.
European Journal of Cancer 39
(6): 801-807.
April 2003
Differential protein expression pattern in tamoxifen-sensitive and -resistant breast cancer xenografts.
Fichtner, I., Becker, M., Besada, V. and Castellanos-Serra, L.
International Journal of Clinical Pharmacology and Therapeutics 42
(11): 632-634.
November 2004
In vivo models for endocrine-dependent breast carcinomas: special considerations of clinical relevance.
Fichtner, I., Becker, M., Zeisig, R. and Sommer, A.
European Journal of Cancer 40
(6): 845-851.
April 2004
The antiangiogenic and antitumoral activity of titanocene Y* in vivo.
Fichtner, I., Behrens, D., Claffey, J., Deally, A., Gleeson, B., Patil, S., Weber, H. and Tacke, M.
Letters in Drug Design & Discovery 8
(4): 302-307.
May 2011
Antitumor activity of oxali-titanocene Y in xenografted CAKI-1 tumors in mice.
Fichtner, I., Behrens, D., Claffey, J., Gleeson, B., Hogan, M., Wallis, D., Weber, H. and Tacke, M.
Letters in Drug Design & Discovery 5
(8): 489-493.
December 2008
In vitro and in vivo investigations into the carbene silver acetate anticancer drug candidate SBC1.
Fichtner, I., Cinatl, J., Michaelis, M., Sanders, L.C., Hilger, R., Kennedy, B.N., Reynolds, A.L., Hackenberg, F., Lally, G., Quinn, S.J., McRae, I. and Tacke, M.
Letters in Drug Design & Discovery 9
(9): 815-822.
November 2012
Antitumor activity of vanadocene Y and its selenocyanate derivative in xenografted CAKI-1 tumors in mice.
Fichtner, I., Claffey, J., Deally, A., Gleeson, B., Hogan, M., Rivera Markelova, M., Mueller-Bunz, H., Weber, H. and Tacke, M.
Journal of Organometallic Chemistry 695
(8): 1175-1181.
15 April 2010
The experimental antitumor agents phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models.
Fichtner, I., Monks, A., Hose, C., Stevens, M.F. and Bradshaw, T.D.
Breast Cancer Research and Treatment 87
(1): 97-107.
1 September 2004
Chemo- and radiation sensitivity of xenografted acute lymphoblastic leukemias-correlation to the expression of multidrug resistance proteins.
Fichtner, I., Paal, K., Borgmann, A., Badiali, L., Wurm, R. and Henze, G.
Anticancer Research 23
(3): 2657-2664.
May 2003
Anti-tumor activity of Titanocene Y in xenografted Caki-1 tumors in mice.
Fichtner, I., Pampillon, C., Sweeney, N.J., Strohfeldt, K. and Tacke, M.
Anti-Cancer Drugs 17
(3): 333-336.
March 2006
In vivo characterization of immunogenicity of a mitoxantrone-resistant murine P388 leukemia.
Fichtner, I., Reipert, B., Becker, M. and Lemm, M.
In Vivo 7
(1): 73-80.
January 1993
Animal experiments - An essential component for the development of liposomal anticancer agents.
Fichtner, I., Reszka, R., Arndt, D. and Zeisig, R.
Journal of Liposome Research 13
(1): 9-15.
3 December 2003
Stimulation of hematopoiesis by carboplatin-liposomes.
Fichtner, I., Reszka, R., Becker, M., Lemm, M., Richter, J. and Rudolph, M.
Journal of Liposome Research 4
(1): 43-69.
March 1994
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.
Fichtner, I., Rolff, J., Soong, R., Hoffmann, J., Hammer, S., Sommer, A., Becker, M. and Merk, J.
Clinical Cancer Research 14
(20): 6456-6468.
15 October 2008
Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas.
Fichtner, I., Slisow, W., Gill, J., Becker, M., Elbe, B., Hillebrand, T. and Bibby, M.
European Journal of Cancer 40
(2): 298-307.
January 2004
Animal models for personalized treatment options.
Fichtner, I., Klinghammer, K., Behrens, D., Flechsig, S., Rolff, J., Becker, M., Wulf-Goldenberg, A., Stecklum, M., Rivera, M., Brzezicha, B., Jandrig, B. and Hoffmann, J.
International Journal of Clinical Pharmacology and Therapeutics 55
(8): 698-700.
August 2017
Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example.
Fingleton, B., Lange, K., Caldwell, B. and Bankaitis, K.V.
Clinical and Experimental Metastasis 34
(8): 443-447.
December 2017
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Finkin, S., Yuan, D., Stein, I., Taniguchi, K., Weber, A., Unger, K., Browning, J.L., Goossens, N., Nakagawa, S., Gunasekaran, G., Schwartz, M.E., Kobayashi, M., Kumada, H., Berger, M., Pappo, O., Rajewsky, K., Hoshida, Y., Karin, M., Heikenwalder, M., Ben-Neriah, Y. and Pikarsky, E.
Nature Immunology 16
(12): 1235-1244.
December 2015
The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Finley, D., Ulrich, H.D., Sommer, T. and Kaiser, P.
Genetics 192
(2): 319-360.
1 October 2012
The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling.
Finsen, A.V., Ueland, T., Sjaastad, I., Ranheim, T., Ahmed, M.S., Dahl, C.P., Askevold, E.T., Aakhus, S., Husberg, C., Fiane, A.E., Lipp, M., Gullestad, L., Christensen, G., Aukrust, P. and Yndestad, A.
PLoS ONE 9
(11): e112172.
14 November 2014
R-spondin-YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.
Fischer, A.S., Müllerke, S., Arnold, A., Heuberger, J., Berger, H., Lin, M., Mollenkopf, H.J., Wizenty, J., Horst, D., Tacke, F. and Sigal, M.
Journal of Clinical Investigation 132
(21): e151363.
1 November 2022
Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils.
Fischer, J., Walter, C., Tönges, A., Aleth, H., Costa Jordão, M.J., Leddin, M., Gröning, V., Erdmann, T., Lenz, G., Roth, J., Vogl, T., Prinz, M., Dugas, M., Jacobsen, I.D. and Rosenbauer, F.
Nature Immunology 20
(5): 546-558.
May 2019
Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC.
Fiskin, E., Lareau, C.A., Ludwig, L.S., Eraslan, G., Liu, F., Ring, A.M., Xavier, R.J. and Regev, A.
Nature Biotechnology 40
(3): 374-381.
March 2022
Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR).
Fitze, G., Appelt, H., Koenig, I.R., Goergens, H., Stein, U., Walther, W., Gossen, M., Schreiber, M., Ziegler, A., Roesner, D. and Schackert, H.K.
Human Molecular Genetics 12
(24): 3207-3214.
1 January 2003
The transcription factor Hey and nuclear lamins specify and maintain cell identity.
Flint Brodsly, N., Bitman-Lotan, E., Boico, O., Shafat, A., Monastirioti, M., Gessler, M., Delidakis, C., Rincon-Arano, H. and Orian, A.
eLife 8
: e44745.
16 July 2019
Long-lasting remission of pulmonary metastases of renal cell cancer under IFN-beta therapy in a patient with multiple sclerosis.
Floercken, A., Denecke, T., Kretzschmar, A., Gollasch, H., Reich, G. and Westermann, J.
Onkologie 29
: 382-384.
September 2006
Severe thrombocytopenia in a patient with metastatic renal cell carcinoma.
Floercken, A., Loew, A., Koch, M., Gebauer, B., Doerken, B. and Riess, H.
Onkologie 32
(11): 670-672.
November 2009
Hepatic arterial infusion chemotherapy for liver metastases from gastric cancer: an analysis in western patients.
Floercken, A., Schaefer, C., Bichev, D., Breithaupt, K., Dogan, Y., Schumacher, G., Gebauer, B., Riess, H., Doerken, B. and Thuss-Patience, P.C.
Tumori 97
(1): 19-24.
January 2011
Sorafenib, but not sunitinib, induces regulatory T cells in the peripheral blood of patients with metastatic renal cell carcinoma.
Floercken, A., Takvorian, A., Van Lessen, A., Singh, A., Hopfenmueller, W., Doerken, B., Pezzutto, A. and Westermann, J.
Anti-Cancer Drugs 23
(3): 298-302.
March 2012
DC generation from peripheral blood mononuclear cells in patients with chronic myeloid leukemia: Influence of interferons on DC yield and functional properties.
Floercken, A., Kopp, J., Kölsch, U., Meisel, C., Dörken, B., Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 12
(5): 1117-1123.
3 May 2016
Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken, A., Grau, M., Wolf, A., Weilemann, A., Kopp, J., Dörken, B., Blankenstein, T., Pezzutto, A., Lenz, P., Lenz, G. and Westermann, J.
International Journal of Cancer 136
(8): 1814-1826.
15 April 2015
Immunomodulatory molecules in renal cell cancer: CD80 and CD86 are expressed on tumor cells.
Flörcken, A., Johannsen, M., Nguyen-Hoai, T., Gerhardt, A., Miller, K., Dörken, B., Pezzutto, A., Westermann, J. and Jöhrens, K.
International Journal of Clinical and Experimental Pathology 10
(2): 1443-1454.
15 February 2017
Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study.
Flörcken, A., Kopp, J., van Lessen, A., Movassaghi, K., Takvorian, A., Jöhrens, K., Möbs, M., Schönemann, C., Sawitzki, B., Egerer, K., Dörken, B., Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9
(7): 1217-1227.
1 June 2013
Myeloid-derived suppressor cells in human peripheral blood: optimized quantification in healthy donors and patients with metastatic renal cell carcinoma.
Flörcken, A., Takvorian, A., Singh, A., Gerhardt, A., Ostendorf, B.N., Dörken, B., Pezzutto, A. and Westermann, J.
Immunology Letters 168
(2): 260-267.
December 2015
Anti-leukemia T cells in AML: TNF-α(+) CD8(+) T cells may escape detection and possibly reflect a stage of functional impairment.
Flörcken, A., van Lessen, A., Terwey, T.H., Dörken, B., Arnold, R., Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9
(7): 1200-1204.
1 June 2013
An autochthonous mouse model of Myd88- and BCL2-driven diffuse large B-cell lymphoma reveals actionable molecular vulnerabilities.
Flümann, R., Rehkämper, T., Nieper, P., Pfeiffer, P., Holzem, A., Klein, S., Bhatia, S., Kochanek, M., Kisis, I., Pelzer, B.W., Ahlert, H., Hauer, J., da Palma Guerreiro, A., Ryan, J.A., Reimann, M., Riabinska, A., Wiederstein, J., Krüger, M., Deckert, M., Altmüller, J., Klatt, A.R., Frenzel, L.P., Pasqualucci, L., Béguelin, W., Melnick, A.M., Sander, S., Montesinos-Rongen, M., Brunn, A., Lohneis, P., Büttner, R., Kashkar, H., Borkhardt, A., Letai, A., Persigehl, T., Peifer, M., Schmitt, C.A., Reinhardt, H.C. and Knittel, G.
Blood Cancer Discovery 2
(1): 70-91.
January 2021
Differentiation of cerebral neoplasms with vessel size imaging (VSI).
Foda, A., Kellner, E., Gunawardana, A., Gao, X., Janz, M., Kufner, A., Khalil, A.A., Geran, R., Mekle, R., Fiebach, J.B. and Galinovic, I.
Clinical Neuroradiology 32
(1): 239-248.
March 2022
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen.
Foerster, R., Mattis, A., Kremmer, E., Wolf, E., Brem, G. and Lipp, M.
Cell 87
(6): 1037-1047.
13 December 1996
CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.
Foerster, R., Schubel, A., Breitfeld, D., Kremmer, E., Renner-Mueller, I., Wolf, E. and Lipp, M.
Cell 99
(1): 23-33.
1 October 1999
Abnormal expression of the b cell homing chemokine receptor blr1 during the progression of acquired immunodeficiency syndrome.
Foerster, R., Schweigard, G., Johann, S., Emrich, T., Kremmer, E., Nerl, C. and Lipp, M.
Blood 90
(2): 520-525.
15 July 1997
THBS4, a novel stromal molecule of diffuse-type gastric adenocarcinomas, identified by transcriptome-wide expression profiling.
Foerster, S., Gretschel, S., Joens, T., Yashiro, M. and Kemmner, W.
Modern Pathology 24
(10): 1390-1403.
October 2011
T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia.
Fogli, L.K., Sundrud, M.S., Goel, S., Bajwa, S., Jensen, K., Derudder, E., Sun, A., Coffre, M., Uyttenhove, C., Van Snick, J., Schmidt-Supprian, M., Rao, A., Grunig, G., Durbin, J., Casola, S.S., Rajewsky, K. and Koralov, S.B.
Journal of Immunology 191
(6): 3100-3111.
15 September 2013
Assessment of curated phenotype mining in neuropsychiatric disorder literature.
Fontaine, J.F., Priller, J., Spruth, E., Perez-Iratxeta, C. and Andrade-Navarro, M.A.
Methods 74
: 90-96.
March 2015
L-glyceraldehyde inhibits neuroblastoma cell growth via a
multi-modal mechanism on metabolism and Signaling.
Forbes, M., Kempa, R., Mastrobuoni, G., Rayman, L., Pietzke, M., Bayram, S., Arlt, B., Spruessel, A., Deubzer, H.E. and Kempa, S.
Cancers 16
(9): 1664.
May 2024
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families.
Ford, D., Easton, D.F., Stratton, M., Narod, S., Goldgar, D., Devilee, P., Bishop, D.T., Weber, B., Lenoir, G., Chang-Claude, J., Sobol, H., Teare, M.D., Struewing, J., Arason, A., Scherneck, S., Peto, J., Rebbeck, T.R., Tonin, P., Neuhausen, S., Barkardottir, R., Eyfjord, J., Lynch, H., Ponder, B.A.J., Gayther, S.A., Birch, J.M., Lindblom, A., Stoppa-Lyonnet, D., Bignon, Y., Borg, A., Hamann, U., Haites, N., Scott, R.J., Maugard, C.M., Vasen, H., Seitz, S., Cannon-Albright, L.A., Schofield, A. and Zelada-Hedman, M.
American Journal of Human Genetics 62
(3): 676-689.
March 1998
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N., Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A., André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M., Cui, C., Daumke, O., Del Bel, K.L., Eibel, H., Feng, X., Franke, V., Gebhardt, J.C.M., Götz, A., Grunwald, S., Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M., Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W., Xiong, E., Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S., Rosenzweig, S.D., Schwarz, K., Turvey, S.E. and Wang, J.Y.
Science Immunology 8
(79): eade7953.
January 2023
PDBpaint, a visualization webservice to tag protein structures with sequence annotations.
Fournier, D. and Andrade-Navarro, M.A.
Bioinformatics 27
(18): 2605-2606.
15 September 2011
Functional and genomic analyses of α-solenoid proteins.
Fournier, D., Palidwor, G.A., Shcherbinin, S., Szengel, A., Schaefer, M.H., Perez-Iratxeta, C. and Andrade-Navarro, M.A.
PLoS ONE 8
(11): e79894.
21 November 2013
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Fox, R.G., Lytle, N.K., Jaquish, D.V., Park, F.D., Ito, T., Bajaj, J., Koechlein, C.S., Zimdahl, B., Yano, M., Kopp, J., Kritzik, M., Sicklick, J., Sander, M., Grandgenett, P.M., Hollingsworth, M.A., Shibata, S., Pizzo, D., Valasek, M., Sasik, R., Scadeng, M., Okano, H., Kim, Y., MacLeod, A.R., Lowy, A.M. and Reya, T.
Nature 534
(7607): 407-411.
16 June 2016
Integrated microfluidic platform for the electrochemical detection of breast cancer markers in patient serum samples.
Fragoso, A., Latta, D., Laboria, N., von Germar, F., Hansen-Hagge, T.E., Kemmner, W., Gaertner, C., Klemm, R., Drese, K.S. and O'Sullivan, C.K.
Lab on a Chip 11
(4): 625-631.
21 February 2011
Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms.
Francavilla, V., Accapezzato, D., De Salvo, M., Rawson, P., Cosimi, O., Lipp, M., Cerino, A., Cividini, A., Mondelli, M.U. and Barnaba, V.
European Journal of Immunology 34
(2): 427-437.
1 January 2004
Keratinocyte-specific ablation of protease-activated receptor-2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease.
Francis, N., Ayodele, B.A., O'Brien-Simpson, N.M., Birchmeier, W., Pike, R.N., Pagel, C.N. and Mackie, E.J.
Cellular Microbiology 20
(11): e12891.
November 2018
Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer.
Francy, C.A., Clinton, R.W., Froehlich, C., Murphy, C. and Mears, J.A.
Scientific Reports 7
(1): 10744.
6 September 2017
CD8-specific designed ankyrin repeat proteins improve selective gene delivery into human and primate T lymphocytes.
Frank, A.M., Weidner, T., Brynza, J., Uckert, W., Buchholz, C.J. and Hartmann, J.
Human Gene Therapy 31
(11-12): 679-691.
June 2020
Substrate binding favors enhanced NO binding to P450cam.
Franke, A., Stochel, G., Jung, C. and van Eldik, R.
Journal of the American Chemical Society 126
(13): 4181-4191.
1 January 2004
Identification of novel ubiquitous and cell type-specific factors that specifically recognize immunoglobulin heavy and light chain promoters.
Franke, S., Scholz, G. and Scheidereit, C.
Journal of Biological Chemistry 269
(31): 20075-20082.
5 August 1994
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Frankell, A.M., Dietzen, M., Al Bakir, M., Lim, E.L., Karasaki, T., Ward, S., Veeriah, S., Colliver, E., Huebner, A., Bunkum, A., Hill, M.S., Grigoriadis, K., Moore, D.A., Black, J.R.M., Liu, W.K., Thol, K., Pich, O., Watkins, T.B.K., Naceur-Lombardelli, C., Cook, D.E., Salgado, R., Wilson, G.A., Bailey, C., Angelova, M., Bentham, R., Martínez-Ruiz, C., Abbosh, C., Nicholson, A.G., Le Quesne, J., Biswas, D., Rosenthal, R., Puttick, C., Hessey, S., Lee, C., Prymas, P., Toncheva, A., Smith, J., Xing, W., Nicod, J., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Blyth, K.G., Fennell, D.A., Forster, M.D., Lee, S.M., Falzon, M., Hewish, M., Shackcloth, M.J., Lim, E., Benafif, S., Russell, P., Boleti, E., Krebs, M.G., Lester, J.F., Papadatos-Pastos, D., Ahmad, T., Thakrar, R.M., Lawrence, D., Navani, N., Janes, S.M., Dive, C., Blackhall, F.H, Summers, Y., Cave, J., Marafioti, T., Herrero, J., Quezada, S.A., Peggs, K.S., Schwarz, R.F., Van Loo, P., Miedema, D.M., Birkbak, N.J., Hiley, C.T., Hackshaw, A., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
(7957): 525-533.
20 April 2023
Influence of CD80, interleukin-2, and interleukin-7 expression in human renal cell carcinoma on the expansion, function, and survival of tumor-specific CTLs.
Frankenberger, B., Pohla, H., Noessner, E., Willimsky, G., Papier, B., Pezzutto, A., Kopp, J., Oberneder, R., Blankenstein, T. and Schendel, D.J.
Clinical Cancer Research 11
: 1733-1742.
1 January 2005
Cell-based vaccines for renal cell carcinoma: genetically-engineered tumor cells and monocyte-derived dendritic cells.
Frankenberger, B., Regn, S., Geiger, C., Noessner, E., Falk, C.S., Pohla, H., Javorovic, M., Silberzahn, T., Wilde, S., Buchner, A., Siebels, M., Oberneder, R., Willimsky, G., Pezzutto, A., Blankenstein, T. and Schendel, D.J.
World Journal of Urology 23
(3): 166-174.
5 July 2005
Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics.
Franz, A., Coscia, F., Shen, C., Charaoui, L., Mann, M. and Sander, C.
Journal of Ovarian Research 14
(1): 140.
22 October 2021
Circular RNAs in clear cell renal cell carcinoma: their microarray-based identification, analytical validation, and potential use in a clinico-genomic model to improve prognostic accuracy.
Franz, A., Ralla, B., Weickmann, S., Jung, M., Rochow, H., Stephan, C., Erbersdobler, A., Kilic, E., Fendler, A. and Jung, K.
Cancers 11
(10): 1473.
30 September 2019
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
Franz, A., Weber, A.I., Preußner, M., Dimos, N., Stumpf, A., Ji, Y., Moreno-Velasquez, L., Voigt, A., Schulz, F., Neumann, A., Kuropka, B., Kuehn, R., Urlaub, H., Schmitz, D., Wahl, M.C. and Heyd, F.
Life Science Alliance 6
(3): e202201826.
March 2023
MYB induces the expression of the oncogenic corepressor SKI in acute myeloid leukemia.
Frech, M., Teichler, S., Feld, C., Bouchard, C., Berberich, H., Sorg, K., Mernberger, M., Bullinger, L., Bauer, U.M. and Neubauer, A.
Oncotarget 9
(32): 22423-22435.
27 April 2018
CAR links hypoxia signaling to improved survival after myocardial infarction.
Freiberg, F., Thakkar, M., Hamann, W., Lopez Carballo, J., Jüttner, R., Voss, F.K., Becher, P.M., Westermann, D., Tschöpe, C., Heuser, A., Rocks, O., Fischer, R. and Gotthardt, M.
Experimental and Molecular Medicine 55
(3): 643-652.
March 2023
The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.
Frese, S., Schubert, W.D., Findeis, A.C., Marquardt, T., Roske, Y.S., Stradal, T.E. and Heinz, D.W.
Journal of Biological Chemistry 281
(26): 18236-18245.
30 June 2006
New insights into the biology of molecular subtypes of diffuse large B-cell lymphoma and Burkitt lymphoma.
Frick, M., Doerken, B. and Lenz, G.
Best Practice and Research Clinical Haematology 25
(1): 3-12.
March 2012
Role of donor clonal hematopoiesis in allogeneic hematopoietic stem-cell transplantation.
Frick, M., Chan, W., Arends, C.M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida, K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhäuser, M., Blau, I.W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E.M., Spriewald, B.M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socié, G., Kroeger, N., Bullinger, L., Thiede, C. and Damm, F.
Journal of Clinical Oncology 37
(5): 375-385.
10 February 2019
Nuclear localization signal and protein context both mediate importin α specificity of nuclear import substrates.
Friedrich, B., Quensel, C., Sommer, T., Hartmann, E. and Koehler, M.
Molecular and Cellular Biology 26
(23): 8697-8709.
December 2006
Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease.
Friedrich, V.D., Pennitz, P., Wyler, E., Adler, J.M., Postmus, D., Müller, K., Teixeira Alves, L.G., Prigann, J., Pott, F., Vladimirova, D., Hoefler, T., Goekeri, C., Landthaler, M., Goffinet, C., Saliba, A.E., Scholz, M., Witzenrath, M., Trimpert, J., Kirsten, H. and Nouailles, G.
EBioMedicine 108
: 105312.
October 2024
High expression level of alpha6 integrin in human breast carcinoma is correlated with reduced survival.
Friedrichs, K., Ruiz, P., Franke, F., Gille, I., Terpe, H.J. and Imhof, B.A.
Cancer Research 55
(4): 901-906.
15 February 1995
Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma.
Friesen, C., Hormann, I., Roscher, M., Fichtner, I., Alt, A., Hilger, R., Debatin, K.M. and Miltner, E.
Cell Cycle 13
(10): 1560-1570.
15 May 2014
Cell death sensitization of leukemia cells by opioid receptor activation.
Friesen, C., Roscher, M., Hormann, I., Fichtner, I., Alt, A., Hilger, R.A., Debatin, K.M. and Miltner, E.
Oncotarget 4
(5): 677-690.
16 April 2013
Therapeutic potential of CAMPATH-1H in skeletal tumours.
Fritsche-Guenther, R., Gruetzkau, A., Noske, A., Melcher, I., Schaser, K.D., Schlag, P.M., Kasper, H.U., Krenn, V. and Sers, C.
Histopathology 57
(6): 851-861.
December 2010
De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway.
Fritsche-Guenther, R., Noske, A., Ungethuem, U., Kuban, R.J., Schlag, P.M., Tunn, P.U., Karle, J., Krenn, V., Dietel, M. and Sers, C.
Histopathology 57
(6): 836-850.
December 2010
Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Fritsche-Guenther, R., Zasada, C., Mastrobuoni, G., Royla, N., Rainer, R., Roßner, F., Pietzke, M., Klipp, E., Sers, C. and Kempa, S.
Scientific Reports 8
(1): 9204.
15 June 2018
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J., Morkel, M., Besser, D., Budczies, J., Kosel, F., Brembeck, F.H., Stein, U., Fichtner, I., Schlag, P.M. and Birchmeier, W.
Gastroenterology 137
(11): 165-175.
July 2009
Einfluss einer praeoperativen (hyperthermen) Radiochemotherapie auf die manometrisch erfasste Analsphinkterfunktion beim lokal fortgeschrittenen Rektumkarzinom [Influence of preoperative (hyperthermic) radiochemotherapy on manometric anal sphincter function in locally advanced rectal cancer].
Fritzmann, J., Huenerbein, M., Slisow, W., Gellermann, J., Wust, P. and Rau, B.
Strahlentherapie und Onkologie 180
: 281-288.
1 May 2004
Association of an impaired GH‑IGF‑I axis with cardiac wasting in patients with advanced cancer.
Fröhlich, A.K., Porthun, J., Talha, K.M., Lena, A., Hadzibegovic, S., Wilkenshoff, U., Sonntag, F., Nikolski, A., Ramer, L.V., Zeller, T., Keller, U., Bullinger, L., Anker, S.D., Haverkamp, W., von Haehling, S., Doehner, W., Rauch, U., Skurk, C., Cleland, J.G.F., Butler, J., Coats, A.J.S., Landmesser, U., Karakas, M. and Anker, M.S.
Clinical Research in Cardiology
8 April 2024
(In Press)
Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein.
Fröhlich, C., Grabiger, S., Schwefel, D., Faelber, K., Rosenbaum, E., Mears, J., Rocks, O. and Daumke, O.
EMBO Journal 32
(9): 1280-1292.
2 May 2013
RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells.
Fu, R., Wellman, K., Baldwin, A., Rege, J., Walters, K., Hirsekorn, A., Riemondy, K., Rainey, W.E and Mukherjee, N.
RNA 27
(8): 933-945.
August 2021
The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.
Fuchs, U., Rehkamp, G., Haas, O.A., Slany, R., Konig, M., Bojesen, S., Bohle, R.M., Damm-Welk, C., Ludwig, W.D., Harbott, J. and Borkhardt, A.
Proceedings of the National Academy of Sciences of the United States of America 98
(15): 8756-8761.
17 July 2001
Follow-up of the GHSG HD16 trial of PET-guided treatment in early-stage favorable Hodgkin lymphoma.
Fuchs, M., Jacob, A.S., Kaul, H., Kobe, C., Kuhnert, G., Pabst, T., Greil, R., Bröckelmann, P.J., Topp, M.S., Just, M., Hertenstein, B., Soekler, M., Vogelhuber, M., Zijlstra, J.M., Keller, U.B., Krause, S.W., Dührsen, U., Meissner, J., Viardot, A., Eich, H.T., Baues, C., Diehl, V., Rosenwald, A., Buehnen, I., von Tresckow, B., Dietlein, M., Borchmann, P., Engert, A. and Eichenauer, D.A.
Leukemia 38
(1): 160-167.
January 2024
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S., Danßmann, C., Klironomos, F., Winkler, A., Fallmann, J., Kruetzfeldt, L.M., Szymansky, A., Naderi, J., Bernhart, S.H., Grunewald, L., Helmsauer, K., Rodriguez-Fos, E., Kirchner, M., Mertins, P., Astrahantseff, K., Suenkel, C., Toedling, J., Meggetto, F., Remke, M., Stadler, P.F., Hundsdoerfer, P., Deubzer, H.E., Künkele, A., Lang, P., Fuchs, J., Henssen, A.G., Eggert, A., Rajewsky, N., Hertwig, F. and Schulte, J.H.
Nature Communications 14
(1): 3936.
4 July 2023
Cellular fingerprints: a novel approach using large-scale cancer cell line data for the identification of potential anticancer agents.
Fuellbeck, M., Dunkel, M., Hossbach, J., Daniel, P.T. and Preissner, R.
Chemical Biology & Drug Design 74
(5): 439-448.
November 2009
Computer-assisted identification of small-molecule Bcl-2 modulators.
Fuellbeck, M., Gebhardt, N., Hossbach, J., Daniel, P.T. and Preissner, R.
Computational Biology and Chemistry 33
(6): 451-456.
December 2009
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice.
Funk, M.C., Gleixner, J.G., Heigwer, F., Vonficht, D., Valentini, E., Aydin, Z., Tonin, E., Del Prete, S., Mahara, S., Throm, Y., Hetzer, J., Heide, D., Stegle, O., Odom, D.T., Feldmann, A., Haas, S., Heikenwalder, M. and Boutros, M.
Developmental Cell 58
(24): 2914-2929.
18 December 2023
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.
Funk, N., Munz, M., Ott, T., Brockmann, K., Wenninger-Weinzierl, A., Kühn, R., Vogt-Weisenhorn, D., Giesert, F., Wurst, W., Gasser, T. and Biskup, S.
Scientific Reports 9
(1): 4515.
14 March 2019
Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line.
Futreal, P.A., Cochran, C., Marks, J.R., Iglehart, J.D., Zimmerman, W., Barrett, J.C. and Wiseman, R.W.
Cancer Research 54
(7): 1791-1794.
1 April 1994
A multimodal platform for simultaneous T-cell imaging, defined activation, and mechanobiological characterization.
Fölser, M., Motsch, V., Platzer, R., Huppa, J.B. and Schütz, G.J.
Cells 10
(2): 235.
February 2021
c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells.
Gabryšová, L., Alvarez-Martinez, M., Luisier, R., Cox, L.S., Sodenkamp, J., Hosking, C., Pérez-Mazliah, D., Whicher, C., Kannan, Y., Potempa, K., Wu, X., Bhaw, L., Wende, H., Sieweke, M.H., Elgar, G., Wilson, M., Briscoe, J., Metzis, V., Langhorne, J., Luscombe, N.M. and O'Garra, A.
Nature Immunology 19
(5): 497-507.
May 2018
Rolle und Aufgaben der chirurgischen Onkologie im Rahmen molekular definierter Therapien [Role and function of surgical oncology in molecular defined therapy].
Gaedcke, J., Schlag, P.M. and Ghadimi, M.
Onkologe 19
(10): 858-862.
October 2013
CT-gesteuerte Resektion pulmonaler Metastasen [CT-guided resection of pulmonary metastases].
Gaffke, G., Stroszczynski, C., Rau, B., Liebeskind, U., Huenerbein, M., Bayraktar, S., Schlag, P.M. and Felix, R.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 177
: 877-883.
1 January 2005
Diagnostik von Duenndarmtumoren mit Hilfe des CT-Entreoklysma : Die CT - Sellink ausgewertet bei 63 Patienten.
Gaffke, G., Stroszczynski, C., Schlecht, I., Jost, D., Ludwig, W.D., Schlag, P.M. and Felix, R.
Roentgenpraxis 54
(6): 214-219.
2002
Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG).
Gaidzik, V.I., Schlenk, R.F., Paschka, P., Stölzle, A., Späth, D., Kuendgen, A., von Lilienfeld-Toal, M., Brugger, W., Derigs, H.G., Kremers, S., Greil, R., Raghavachar, A., Ringhoffer, M., Salih, H.R., Wattad, M., Kirchen, H.G., Runde, V., Heil, G., Petzer, A.L., Girschikofsky, M., Heuser, M., Kayser, S., Goehring, G., Teleanu, M.V., Schlegelberger, B., Ganser, A., Krauter, J., Bullinger, L., Döhner, H. and Döhner, K.
Blood 121
(23): 4769-77.
6 June 2013
RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features.
Gaidzik, V.I., Teleanu, V., Papaemmanuil, E., Weber, D., Paschka, P., Hahn, J., Wallrabenstein, T., Kolbinger, B., Köhne, C.H., Horst, H.A., Brossart, P., Held, G., Kündgen, A., Ringhoffer, M., Götze, K., Rummel, M., Gerstung, M., Campbell, P., Kraus, J.M., Kestler, H.A., Thol, F., Heuser, M., Schlegelberger, B., Ganser, A., Bullinger, L., Schlenk, R.F., Döhner, K. and Döhner, H.
Leukemia 30
(11): 2160-2168.
November 2016
DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia.
Gaidzik, V.I., Weber, D., Paschka, P., Kaumanns, A., Krieger, S., Corbacioglu, A., Krönke, J., Kapp-Schwoerer, S., Krämer, D., Horst, H.A., Schmidt-Wolf, I., Held, G., Kündgen, A., Ringhoffer, M., Götze, K., Kindler, T., Fiedler, W., Wattad, M., Schlenk, R.F., Bullinger, L., Teleanu, V., Schlegelberger, B., Thol, F., Heuser, M., Ganser, A., Döhner, H. and Döhner, K.
Leukemia 32
(1): 30-37.
January 2018
Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes.
Gainullina, A., Mogilenko, D.A., Huang, L.H., Todorov, H., Narang, V., Kim, K.W., Yng, L.S., Kent, A., Jia, B., Seddu, K., Krchma, K., Wu, J., Crozat, K., Tomasello, E., Dress, R., See, P., Scott, C., Gibbings, S., Bajpai, G., Desai, J.V., Maier, B., This, S., Wang, P., Aguilar, S.V., Poupel, L., Dussaud, S., Zhou, T.A., Angeli, V., Blander, J.M., Choi, K., Dalod, M., Dzhagalov, I., Gautier, E.L., Jakubzick, C., Lavine, K., Lionakis, M.S., Paidassi, H., Sieweke, M.H., Ginhoux, F., Guilliams, M., Benoist, C., Merad, M., Randolph, G.J., Sergushichev, A. and Artyomov, M.N.
Cell Reports 42
(2): 112046.
28 February 2023
Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.
Gaiser, O.J., Ball, L.J., Schmieder, P., Leitner, D., Strauss, H., Wahl, M., Kuehne, R., Oschkinat, H. and Heinemann, U.
Biochemistry 43
(51): 15983-15995.
1 January 2004
Structural basis for the substrate specificity of a Bacillus 1,3-1,4-beta-glucanase.
Gaiser, O.J., Piotukh, K., Ponnuswamy, W.N., Planas, A., Borriss, R. and Heinemann, U.
Journal of Molecular Biology 357
(4): 1211-1225.
7 April 2006
Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects.
Galgoczi, S., Ruzo, A., Markopoulos, C., Yoney, A., Phan-Everson, T., Li, S., Haremaki, T., Metzger, J.J., Etoc, F. and Brivanlou, A.H.
Development 148
(19): dev199513.
October 2021
Natural course of untreated microalbuminuria in children and adolescents with type 1 diabetes and the importance of diabetes duration and immigrant status: longitudinal analysis from the prospective nationwide German and Austrian diabetes survey DPV.
Galler, A., Haberland, H., Naeke, A., Hofer, S., Holder, M., Raile, K. and Holl, R.W.
European Journal of Endocrinology 166
(3): 493-501.
March 2012
Associations between media consumption habits, physical activity, socioeconomic status, and glycemic control in children, adolescents, and young adults with type 1 diabetes.
Galler, A., Lindau, M., Ernert, A., Thalemann, R. and Raile, K.
Diabetes Care 34
(11): 2356-2359.
November 2011
Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer.
Galling, N., Kobelt, D., Aumann, J., Schmidt, M., Wittig, B., Schlag, P.M. and Walther, W.
Human Gene Therapy Part B Methods 23
(4): 264-270.
August 2012
A conserved noncoding locus regulates random monoallelic Xist expression across a topological boundary.
Galupa, R., Nora, E.P., Worsley-Hunt, R., Picard, C., Gard, C., van Bemmel, J.G., Servant, N., Zhan, Y., El Marjou, F., Johanneau, C., Diabangouaya, P., Le Saux, A., Lameiras, S., Pipoli da Fonseca, J., Loos, F., Gribnau, J., Baulande, S., Ohler, U., Giorgetti, L. and Heard, E.
Molecular Cell 77
(2): 352-367.
16 January 2020
Landscape of HER2-low metastatic breast cancer (MBC): results from the Austrian AGMT_MBC-Registry.
Gampenrieder, S.P., Rinnerthaler, G., Tinchon, C., Petzer, A., Balic, M., Heibl, S., Schmitt, C., Zabernigg, A.F., Egle, D., Sandholzer, M., Singer, C.F., Roitner, F., Hager, C., Andel, J., Hubalek, M., Knauer, M. and Greil, R.
Breast Cancer Research 23
(1): 112.
14 December 2021
The Chriz-Z4 complex recruits JIL-1 to polytene chromosomes, a requirement for interband-specific phosphorylation of H3S10.
Gan, M., Moebus, S., Eggert, H. and Saumweber, H.
Journal of Biosciences 36
(3): 425-438.
August 2011
Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Ganichkin, O.M., Vancraenenbroeck, R., Rosenblum, G., Hofmann, H., Mikhailov, A.S., Daumke, O. and Noel, J.K.
Proceedings of the National Academy of Sciences of the United States of America 118
(28): e2101144118.
13 July 2021
Structure of myxovirus resistance protein A reveals intra- and intermolecular domain interactions required for the antiviral function.
Gao, S., von der Malsburg, A., Dick, A., Faelber, K., Schroeder, G.F., Haller, O., Kochs, G. and Daumke, O.
Immunity 35
(4): 514-525.
28 October 2011
Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao, S., von der Malsburg, A., Paeschke, S., Behlke, J., Haller, O., Kochs, G. and Daumke, O.
Nature 465
(7297): 502-506.
27 May 2010
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.
Garces de Los Fayos Alonso, I., Zujo, L., Wiest, I., Kodajova, P., Timelthaler, G., Edtmayer, S., Zrimšek, M., Kollmann, S., Giordano, C., Kothmayer, M., Neubauer, H.A., Dey, S., Schlederer, M., Schmalzbauer, B.S., Limberger, T., Probst, C., Pusch, O., Högler, S., Tangermann, S., Merkel, O., Schiefer, A.I., Kornauth, C., Prutsch, N., Zimmerman, M., Abraham, B., Anagnostopoulos, J., Quintanilla-Martinez, L., Mathas, S., Wolf, P., Stoiber, D., Staber, P.B., Egger, G., Klapper, W., Woessmann, W., Look, T.A., Gunning, P., Turner, S.D., Moriggl, R., Lagger, S. and Kenner, L.
Molecular Cancer 21
(1): 172.
31 August 2022
Positive and negative unintended human-induced effects on Iberian mole abundance at the edge of its distribution area.
García-López de Hierro, L., Moleón, M., Lupiáñez, D.G., Virgós, E. and Jiménez, R.
Mammalian Biology 78
(4): 276-282.
June 2013
A novel form of RNA double helix based on G·U and C·A(+) wobble base pairing.
Garg, A. and Heinemann, U.
RNA 24
(2): 209-218.
February 2018
PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Garg, A., Roske, Y., Yamada, S., Uehata, T., Takeuchi, O. and Heinemann, U.
Nucleic Acids Research 49
(9): 5369-5381.
21 May 2021
In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.
Gargiulo, G., Cesaroni, M., Serresi, M., de Vries, N., Hulsman, D., Bruggeman, S.W., Lancini, C. and van Lohuizen, M.
Cancer Cell 23
(5): 660-676.
13 May 2013
Polycomb and lung cancer: when the dosage makes the (kind of) poison.
Gargiulo, G., Citterio, E. and Serresi, M.
Molecular & Cellular Oncology 3
(3): e1152345.
May 2016
NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation.
Gargiulo, G., Levy, S., Bucci, G., Romanenghi, M., Fornasari, L., Beeson, K.Y., Goldberg, S.M., Cesaroni, M., Ballarini, M., Santoro, F., Bezman, N., Frige, G., Gregory, P.D., Holmes, M.C., Strausberg, R.L., Pelicci, P.G., Urnov, F.D. and Minucci, S.
Developmental Cell 16
(3): 466-481.
17 March 2009
In vivo shRNA screens in solid tumors.
Gargiulo, G., Serresi, M., Cesaroni, M., Hulsman, D. and van Lohuizen, M.
Nature Protocols 9
(12): 2880-2902.
December 2014
Cell states in cancer: drivers, passengers, and trailers.
Gargiulo, G., Serresi, M. and Marine, J.C.
Cancer Discovery 14
(4): 610-614.
4 April 2024
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.
Garipler, G., Lu, C., Morrissey, Al., Lopez-Zepeda, L.S., Pei, Y., Vidal, S.E., Zen Petisco Fiore, A.P., Aydin, B., Stadtfeld, M., Ohler, U., Mahony, S., Sanjana, N.E. and Mazzoni, E.O.
Cell Reports 38
(11): 110524.
15 March 2022
Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and expansion of cTfh1 cells and impaired B memory cell formation.
Garner-Spitzer, E., Wagner, A., Gudipati, V., Schoetta, A.M., Orola-Taus, M., Kundi, M., Kunert, R., Mayrhofer, P., Huppa, J.B., Stockinger, H., Carsetti, R., Gattinger, P., Valenta, R., Kratzer, B., Sehgal, A.N.A., Pickl, W.F., Reinisch, W., Novacek, G. and Wiedermann, U.
EBioMedicine 96
: 104788.
October 2023
SARS-CoV-2-specific antibody (Ab) levels and the kinetic of ab decline determine Ab persistence over 1 year.
Garner-Spitzer, E., Wagner, A., Kundi, M., Stockinger, H., Ohradanova-Repic, A., Gebetsberger, L., Schoetta, A.M., Gudipati, V., Huppa, J.B., Kunert, R., Mayrhofer, P., Kreil, T.R., Farcet, M.R., Hoeltl, E. and Wiedermann, U.
Frontiers in Medicine 9
: 822316.
15 February 2022
IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis.
Garnier, L., Pick, R., Montorfani, J., Sun, M., Brighouse, D., Liaudet, N., Kammertoens, T., Blankenstein, T., Page, N., Bernier-Latamani, J., Tran, N.L., Petrova, T.V., Merkler, D., Scheiermann, C. and Hugues, S.
Science Advances 8
(23): eabl5162.
8 June 2022
Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors.
Garrett, L., Zhang, J., Zimprich, A., Niedermeier, K.M., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Vogt Weisenhorn, D., Wurst, W. and Hoelter, S.M.
Frontiers in Behavioral Neuroscience 9
: 302.
12 November 2015
Luminal particles within cellular microtubules.
Garvalov, B.K., Zuber, B., Bouchet-Marquis, C., Kudryashev, M., Gruska, M., Beck, M., Leis, A., Frischknecht, F., Bradke, F., Baumeister, W., Dubochet, J. and Cyrklaff, M.
Journal of Cell Biology 174
(6): 759-765.
11 September 2006
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions.
Garvanska, D.H., Alvarado, R.E., Mundt, F.O., Lindqvist, R., Duel, J.K., Coscia, F., Nilsson, E., Lokugamage, K., Johnson, B.A., Plante, J.A., Morris, D.R., Vu, M.N., Estes, L.K., McLeland, A.M., Walker, J., Crocquet-Valdes, P.A., Mendez, B.L., Plante, K.S., Walker, D.H., Weisser, M.B., Överby, A.K., Mann, M., Menachery, V.D. and Nilsson, J.
EMBO Reports 25
(2): 902-926.
13 February 2024
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Gassen, N.C., Papies, J., Bajaj, T., Emanuel, J., Dethloff, F., Chua, R.L., Trimpert, J., Heinemann, N., Niemeyer, C., Weege, F., Hönzke, K., Aschman, T., Heinz, D.E., Weckmann, K., Ebert, T., Zellner, A., Lennarz, M., Wyler, E., Schroeder, S., Richter, A., Niemeyer, D., Hoffmann, K., Meyer, T.F., Heppner, F.L., Corman, V.M., Landthaler, M., Hocke, A.C., Morkel, M., Osterrieder, N., Conrad, C., Eils, R., Radbruch, H., Giavalisco, P., Drosten, C. and Müller, M.A.
Nature Communications 12
(1): 3818.
21 June 2021
A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
Gauss, R., Jarosch, E., Sommer, T. and Hirsch, C.
Nature Cell Biology 8
(8): 849-854.
August 2006
The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment.
Gauss, R., Sommer, T. and Jarosch, E.
EMBO Journal 25
(9): 1827-1835.
3 May 2006
New modules for the repeated internal and N-terminal epitope tagging of genes in Saccharomyces cerevisiae.
Gauss, R., Trautwein, M., Sommer, T. and Spang, A.
Yeast 22
(1): 1-12.
1 January 2005
A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells.
Gavvovidis, I., Rost, I., Trimborn, M., Kaiser, F.J., Purps, J., Wiek, C., Hanenberg, H., Neitzel, H. and Schindler, D.
PLoS ONE 7
(8): e40387.
30 August 2012
Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.
Gavvovidis, I., Leisegang, M., Willimsky, G., Miller, N.J., Nghiem, P. and Blankenstein, T.
Clinical Cancer Research 24
(15): 3644-3655.
August 2018
Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia.
Gazda, H.T., Grabowska, A., Merida-Long, L.B., Latawiec, E., Schneider, H.E., Lipton, J.M., Vlachos, A., Atsidaftos, E., Ball, S.E., Orfali, K.A., Niewiadomska, E., Da Costa, L., Tchernia, G., Niemeyer, C., Meerpohl, J.J., Stahl, J., Schratt, G., Glader, B., Backer, K., Wong, C., Nathan, D.G., Beggs, A.H. and Sieff, C.A.
American Journal of Human Genetics 79
(6): 1110-1118.
December 2006
Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.
Gazumyan, A., Timachova, K., Yuen, G., Siden, E., Di Virgilio, M., Woo, E.M., Chait, B.T., Reina San-Martin, B., Nussenzweig, M.C. and McBride, K.M.
Molecular and Cellular Biology 31
(3): 442-429.
February 2011
Magnetic resonance-guided biopsy of suspicious breast lesions with a handheld vacuum biopsy device.
Gebauer, B., Bostanjoglo, M., Moesta, K.T., Schneider, W., Schlag, P.M. and Felix, R.
Acta Radiologica 47
(9): 907-913.
November 2006
mBISON: Finding miRNA target over-representation in gene lists from ChIP-sequencing data.
Gebhardt, M.L., Mer, A.S. and Andrade-Navarro, M.A.
BMC Research Notes 8
(1): 157.
16 April 2015
Similarity in targets with REST points to neural and glioblastoma related miRNAs.
Gebhardt, M.L., Reuter, S., Mrowka, R. and Andrade-Navarro, M.A.
Nucleic Acids Research 42
(9): 5436-5446.
14 May 2014
New role for the (pro)renin receptor in T cell development.
Geisberger, S., Maschke, U., Gebhardt, M., Kleinewietfeld, M., Manzel, A., Linker, R.A., Chidgey, A., Dechend, R., Nguyen, G., Daumke, O., Muller, D.N., Wright, M.D. and Binger, K.J.
Blood 126
(4): 504-507.
23 July 2015
BTK inhibition limits microglia‑perpetuated CNS inflammation and promotes myelin repair.
Geladaris, A., Torke, S., Saberi, D., Alankus, Y.B., Streit, F., Zechel, S., Stadelmann-Nessler, C., Fischer, A., Boschert, U., Häusler, D. and Weber, M.S.
Acta Neuropathologica 147
(1): 75.
24 April 2024
Bruton's tyrosine kinase inhibitors in multiple sclerosis: pioneering the path towards treatment of progression?
Geladaris, A., Torke, S. and Weber, M.S.
CNS drugs 36
(10): 1019-1030.
October 2022
First genome-wide CNV mapping in FELIS CATUS using next generation sequencing data.
Genova, F., Longeri, M., Lyons, L.A., Bagnato, A. and Strillacci, M.G.
BMC Genomics 19
(1): 895.
10 December 2018
Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg, P., Astaburuaga-García, R., Bonaguro, L., Brumhard, S., Michalick, L., Lippert, L.J., Kostevc, T., Gäbel, C., Schneider, M., Streitz, M., Demichev, V., Gemünd, I., Barone, M., Tober-Lau, P., Helbig, E.T., Hillus, D., Petrov, L., Stein, J., Dey, H.P., Paclik, D., Iwert, C., Mülleder, M., Aulakh, S.K., Djudjaj, S., Bülow, R.D., Mei, H.E., Schulz, A.R., Thiel, A., Hippenstiel, S., Saliba, A.E., Eils, R., Lehmann, I., Mall, M.A., Stricker, S., Röhmel, J., Corman, V.M., Beule, D., Wyler, E., Landthaler, M., Obermayer, B., von Stillfried, S., Boor, P., Demir, M., Wesselmann, H., Suttorp, N., Uhrig, A., Müller-Redetzky, H., Nattermann, J., Kuebler, W.M., Meisel, C., Ralser, M., Schultze, J.L., Aschenbrenner, A.C., Thibeault, C., Kurth, F., Sander, L.E., Blüthgen, N. and Sawitzki, B.
Cell 185
(3): 493-512.
3 February 2022
Evidence-ranked motif identification.
Georgiev, S., Boyle, A.P., Jayasurya, K., Ding, X., Mukherjee, S. and Ohler, U.
Genome Biology 11
(2): R19.
15 February 2010
Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.
Gerbitz, A., Sukumar, M., Helm, F., Wilke, A., Friese, C., Fahrenwaldt, C., Lehmann, F.M., Loddenkemper, C., Kammertoens, T., Mautner, J., Schmitt, C.A., Blankenstein, T. and Bornkamm, G.W.
PLoS ONE 7
(3): e34552.
30 March 2012
Interwoven four-compartment capillary membrane technology for three-dimensional perfusion with decentralized mass exchange to scale up embryonic stem cell culture.
Gerlach, J., Luebberstedt, M., Edsbagge, J., Ring, A., Hout, M., Baun, M., Rossberg, I., Knoespel, F., Peters, G., Eckert, K., Wulf-Goldenberg, A., Bjoerquist, P., Stachelscheid, H., Urbaniak, T., Schatten, G., Miki, T., Schmelzer, E. and Zeilinger, K.
Cells Tissues Organs 192
(1): 39-49.
June 2010
pH-dependent protonation of surface carboxylate groups in PsbO enables local buffering and triggers structural changes.
Gerland, L. M., Friedrich, D., Hopf, L., Donovan, E., Wallmann, A., Erdmann, N., Diehl, A., Bommer, M., Buzar, K., Ibrahim, M., Schmieder, P., Dobbek, H., Zouni, A., Bondar, A.-N., Dau, H. and Oschkinat, H.
ChemBioChem 21
(11): 1597-1604.
2 June 2020
Precision oncology for acute myeloid leukemia using a knowledge bank approach.
Gerstung, M., Papaemmanuil, E., Martincorena, I., Bullinger, L., Gaidzik, V.I., Paschka, P., Heuser, M., Thol, F., Bolli, N., Ganly, P., Ganser, A., McDermott, U., Döhner, K., Schlenk, R.F., Döhner, H. and Campbell, P.J.
Nature Genetics 49
(3): 332-340.
March 2017
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B., Heuser, A., Wichter, T., Paul, M., Basson, C.T., McDermott, D.A., Lerman, B.B., Markowitz, S.M., Ellinor, P.T., MacRae, C.A., Peters, S., Grossmann, K.S., Drenckhahn, J., Michely, B., Sasse-Klaassen, S., Birchmeier, W., Dietz, R., Breithardt, G., Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36
(11): 1162-1164.
November 2004
Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: Implications for cell adhesion and signaling.
Ghadimi, B.M., Behrens, J., Hoffmann, I., Haensch, W., Birchmeier, W. and Schlag, P.M.
European Journal of Cancer 35
(1): 60-65.
January 1999
Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer.
Ghadjar, P., Coupland, S.E., Na, I.K., Noutsias, M., Letsch, A., Stroux, A., Bauer, S., Buhr, H.J., Thiel, E., Scheibenbogen, C. and Keilholz, U.
Journal of Clinical Oncology 24
(12): 1910-1916.
20 April 2006
Deep neural networks for interpreting RNA-binding protein target preferences.
Ghanbari, M. and Ohler, U.
Genome Research 30
(2): 214-226.
February 2020
Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S., Riemke, P., Schoenheit, J., Lenze, D., Stumm, J., Hoogenkamp, M., Lagendijk, A., Heinz, S., Bonifer, C., Bakkers, J., Abdelilah-Seyfried, S., Hummel, M. and Rosenbauer, F.
Blood 118
(8): 2275-2284.
25 August 2011
Strand-seq enables reliable separation of long reads by chromosome via expectation maximization.
Ghareghani, M., Porubskỳ, D., Sanders, A.D., Meiers, S., Eichler, E.E., Korbel, J.O. and Marschall, T.
Bioinformatics 34
(13): i115-i123.
1 July 2018
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Ghorashian, S., Veliça, P., Chua, I., McNicol, A., Carpenter, B., Holler, A., Nicholson, E., Ahmadi, M., Zech, M., Xue, S., Uckert, W., Morris, E., Chakraverty, R. and Stauss, H.J.
Journal of Immunology 194
(3): 1080-1089.
1 February 2015
PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating graft-versus-host-disease.
Ghosh, A., Holland, A.M., Dogan, Y., Yim, N., Rao, U.K., Young, L.F., West, M.L., Singer, N.V., Lee, H., Na, I.K., Tsai, J.J., Jenq, R., Penack, O., Hanash, A.M., Lezcano, C., Murphy, G.F., Liu, C., Sadelain, M., Sauer, M.G., Sant'Angelo, D. and van den Brink, M.R.M.
Cancer Research 73
(15): 4687-4696.
1 August 2013
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.
Giacopelli, B., Wang, M., Cleary, A., Wu, Y.Z., Schultz, A.R., Schmutz, M., Blachly, J.S., Eisfeld, A.K., Mundy-Bosse, B., Vosberg, S., Greif, P.A., Claus, R., Bullinger, L., Garzon, R., Coombes, K.R., Bloomfield, C.D., Druker, B.J., Tyner, J.W., Byrd, J.C. and Oakes, C.C.
Genome Research 31
(5): 747-761.
May 2021
Targeted application of human genetic variation can improve red blood cell production from stem cells.
Giani, F.C., Fiorini, C., Wakabayashi, A., Ludwig, L.S., Salem, R.M., Jobaliya, C.D., Regan, S.N., Ulirsch, J.C., Liang, G., Steinberg-Shemer, O., Guo, M.H., Esko, T., Tong, W., Brugnara, C., Hirschhorn, J.N., Weiss, M.J., Zon, L.I., Chou, S.T., French, D.L., Musunuru, K. and Sankaran, V.G.
Cell Stem Cell 18
(1): 73-78.
7 January 2016
TERT core promotor mutations in early-onset bladder cancer.
Giedl, J., Rogler, A., Wild, A., Riener, M.O., Filbeck, T., Burger, M., Ruemmele, P., Hurst, C., Knowles, M., Hartmann, A., Zinnall, U. and Stoehr, R.
Journal of Cancer 7
(8): 915-920.
7 May 2016
Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex.
Giehler, F., Ostertag, M.S., Sommermann, T., Weidl, D., Sterz, K.R., Kutz, H., Moosmann, A., Feller, S.M., Geerlof, A., Biesinger, B., Popowicz, G.M., Kirchmair, J. and Kieser, A.
Nature Communications 15
(1): 414.
10 January 2024
Alkemio: association of chemicals with biomedical topics by text and data mining.
Gijon-Correas, J.A., Andrade-Navarro, M.A. and Fontaine, J.F.
Nucleic Acids Research 42
(W1): W422-W429.
1 July 2014
Cxcl10(+) monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation.
Giladi, A., Wagner, L.K., Li, H., Dörr, D., Medaglia, C., Paul, F., Shemer, A., Jung, S., Yona, S., Mack, M., Leutz, A., Amit, I. and Mildner, A.
Nature Immunology 21
(5): 525-534.
May 2020
Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
Gillissen, B., Essmann, F., Graupner, V., Staerck, L., Radetzki, S., Doerken, B., Schulze-Osthoff, K. and Daniel, P.T.
EMBO Journal 22
(14): 3580-3590.
15 July 2003
Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
Gillissen, B., Essmann, F., Hemmati, P.G., Richter, A., Richter, A., Oztop, I., Chinnadurai, G., Doerken, B. and Daniel, P.T.
Journal of Cell Biology 179
(4): 701-715.
19 November 2007
Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode.
Gillissen, B., Richter, A., Richter, A., Overkamp, T., Essmann, F., Hemmati, P.G., Preissner, R., Belka, C. and Daniel, P.T.
Cell Death & Disease 4
: e643.
23 May 2013
Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin.
Gillissen, B., Richter, A., Essmann, F. and Kemmner, W.
BMC Cancer 21
(1): 971.
30 August 2021
Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B., Richter, A., Richter, A., Preissner, R., Schulze-Osthoff, K., Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292
(16): 6478-6492.
21 April 2017
Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.
Gillissen, B., Wendt, J., Richter, A., Richter, A., Mueer, A., Overkamp, T., Gebhardt, N., Preissner, R., Belka, C., Doerken, B. and Daniel, P.T.
Journal of Cell Biology 188
(6): 851-862.
22 March 2010
GPSeq reveals the radial organization of chromatin in the cell nucleus.
Girelli, G., Custodio, J., Kallas, T., Agostini, F., Wernersson, E., Spanjaard, B., Mota, A., Kolbeinsdottir, S., Gelali, E., Crosetto, N. and Bienko, M.
Nature Biotechnology 38
(10): 1184-1193.
October 2020
Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data using Decoil.
Giurgiu, M., Wittstruck, N., Rodriguez-Fos, E., Chamorro González, R., Brückner, L., Krienelke-Szymansky, A., Helmsauer, K., Hartebrodt, A., Euskirchen, P., Koche, R.P., Haase, K., Reinert, K. and Henssen, A.G.
Genome Research 34
(9): 1355-1364.
September 2024
Decoil: reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data.
Giurgiu, M., Wittstruck, N., Rodriguez-Fos, E., Chamorro González, R., Brückner, L., Krienelke-Szymansky, A., Helmsauer, K., Hartebrodt, A., Euskirchen, P., Koche, R.P., Haase, K., Reinert, K. and Henssen, A.G.
Lecture Notes in Computer Science 14758
: 406-411.
17 May 2024
Dual T cell receptor T cells with two defined specificities mediate tumor suppression via both receptors.
Gladow, M., Uckert, W. and Blankenstein, T.
European Journal of Immunology 34
(7): 1882-1891.
1 July 2004
NKp46 receptor-mediated interferon-γ production by natural killer cells increases fibronectin 1 to alter tumor architecture and control metastasis.
Glasner, A., Levi, A., Enk, J., Isaacson, B., Viukov, S., Orlanski, S., Scope, A., Neuman, T., Enk, C.D., Hanna, J.H., Sexl, V., Jonjic, S., Seliger, B., Zitvogel, L. and Mandelboim, O.
Immunity 48
(1): 107-119.
16 January 2018
A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use.
Gleicher, N., Metzger, J., Croft, G., Kushnir, V.A., Albertini, D.F. and Barad, D.H.
Reproductive Biology and Endocrinology 15
(1): 33.
27 April 2017
Characterization of the recombinant adenovirus vector AdYB-1: implications for oncolytic vector development.
Glockzin, G., Mantwill, K., Juerchott, K., Bernshausen, A., Ladhoff, A., Royer, H.D., Gansbacher, B. and Holm, P.S.
Journal of Virology 80
: 3904-3911.
15 April 2006
Lymphoma angiogenesis is orchestrated by noncanonical signaling pathways.
Gloger, M., Menzel, L., Grau, M., Vion, A.C., Anagnostopoulos, I., Zapukhlyak, M., Gerlach, K., Kammertöns, T., Hehlgans, T., Zschummel, M., Lenz, G., Gerhardt, H., Höpken, U.E. and Rehm, A.
Cancer Research 80
(6): 1316-1329.
March 2020
An unusual aspartic acid cluster in the reovirus attachment fiber s1 mediates stability at low pH and preserves trimeric organization.
Glorani, G., Ruwolt, M., Holton, N., Loll, B. and Neu, U.
Journal of Virology 96
(8): e0033122.
April 2022
Recombinant human erythropoietin, epoetin beta, in patients with relapsed lymphoma treated with aggressive sequential salvage chemotherapy - results of a randomized trial.
Glossmann, J.P., Engert, A., Wassmer, G., Flechtner, H., Ko, Y., Rudolph, C., Metzner, B., Doerken, B., Wiedenmann, S., Diehl, V. and Josting, A.
Annals of Hematology 82
(8): 469-475.
1 August 2003
The severe combined immunodeficient-human peripheral blood stem cell (SCID-huPBSC) mouse: a xenotransplant model for huPBSC-initiated hematopoiesis.
Goan, S.R., Fichtner, I., Just, U., Karawajew, L., Schultze, W., Krause, K.P., von Harsdorf, S., von Schilling, C. and Herrmann, F.
Blood 86
(1): 89-100.
1 July 1995
Lymphomas are sensitive to perforin-dependent cytotoxic pathways despite expression of PI-9 and overexpression of bcl-2.
Godal, R., Keilholz, U., Uharek, L., Letsch, A., Asemissen, A.M., Busse, A., Na, I.K., Thiel, E. and Scheibenbogen, C.
Blood 107
(8): 3205-3211.
15 April 2006
Axon guidance factor Slit2 inhibits neural invasion and metastasis in pancreatic cancer.
Goehrig, A., Detjen, K.M., Hilfenhaus, G., Koerner, J., Welzel, M., Arsenic, R., Schmuck, R., Bahra, M., Wu, J.Y., Wiedenmann, B. and Fischer, C.
Cancer Research 74
(5): 1529-1540.
1 March 2014
Importin provides a link between nuclear protein import and U snRNA export.
Goerlich, D., Kraft, R., Kostka, S., Vogel, F., Hartmann, E., Laskey, R.A., Mattaj, I.W. and Izaurralde, E.
Cell 87
(1): 21-32.
4 October 1996
The impact of short-term psycho-oncological interventions on the psychological outcome of cancer patients of a surgical-oncology department - A randomised controlled study.
Goerling, U., Foerg, A., Sander, S., Schramm, N. and Schlag, P.M.
European Journal of Cancer 47
(13): 2009-2014.
September 2011
Psychosozialer Betreuungsbedarf bei stationaeren Tumorpatienten. Untersuchungen an einer chirurgisch-onkologischen Schwerpunktklinik [Need for psychosocial care in in-patients with tumour disease. Investigations conducted in a clinic specializing in tumour surgery.].
Goerling, U., Odebrecht, S., Schiller, G. and Schlag, P.M.
Chirurg 77
: 41-46.
January 2006
Die Szenario-Methode als Verfahren zur Buergerbeteiligung? Staerken, Schwaechen, Moeglichkeiten und Problemquellen aus der Sicht von Teilnehmern des Workshops "Die Grenzen von Genen, Geld und Gelehrten".
Goersdorf, A. and Tannert, C.
Zeitschrift fuer Biopolitik 3
(1): 49-59.
1 January 2004
Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells.
Gogol-Döring, A., Ammar, I., Gupta, S., Bunse, M., Miskey, C., Chen, W., Uckert, W., Schulz, T.F., Izsvák, Z. and Ivics, Z.
Molecular Therapy 24
(3): 592-606.
March 2016
CancerResource - updated database of cancer-relevant proteins, mutations and interacting drugs.
Gohlke, B.O., Nickel, J., Otto, R., Dunkel, M. and Preissner, R.
Nucleic Acids Research 44
(D1): D932-D937.
4 January 2016
2D and 3D similarity landscape analysis identifies PARP as a novel off-target for the drug Vatalanib.
Gohlke, B.O., Overkamp, T., Richter, A., Richter, A., Daniel, P.T., Gillissen, B. and Preissner, R.
BMC Bioinformatics 16
(1): 308.
24 September 2015
Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O., Zincke, F., Eckert, A., Kobelt, D., Preissner, S., Liebeskind, J.M., Gunkel, N., Putzker, K., Lewis, J., Preissner, S., Kortüm, B., Walther, W., Mura, K., Bourne, P.E., Stein, U. and Preissner, R.
Clinical and Translational Medicine 12
(2): e726.
20 February 2022
Recent progress in structure and dynamics of dual-membrane-spanning bacterial nanomachines.
Gold, V. and Kudryashev, M.
Current Opinion in Structural Biology 39
: 1-7.
August 2016
Tissue factor expression pattern in human non-small cell lung cancer tissues indicate increased blood thrombogenicity and tumor metastasis.
Goldin-Lang, P., Tran, Q.V., Fichtner, I., Eisenreich, A., Antoniak, S., Schulze, K., Coupland, S.E., Poller, W., Schultheiss, H.P. and Rauch, U.
Oncology Reports 20
(1): 123-128.
July 2008
Thomsen-Friedenreich antigen: the "hidden" tumor antigen.
Goletz, S., Cao, Y., Danielczyk, A., Ravn, P., Schoeber, U. and Karsten, U.
Advances in Experimental Medicine and Biology 535
: 147-162.
1 January 2003
Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4.
Golfier, S., Kondo, S., Schulze, T., Takeuchi, T., Vassileva, G., Achtman, A.H., Graeler, M.H., Abbondanzo, S.J., Wiekowski, M., Kremmer, E., Endo, Y., Lira, S.A., Bacon, K.B. and Lipp, M.
FASEB Journal 24
(12): 4701-4710.
December 2010
Manufacture of gene modified human T cells with a memory stem/ central memory phenotype.
Gomez-Eerland, R., Nuijen, B., Heemskerk, B., van Rooij, N., van den Berg, J.H., Beijnen, J.H., Uckert, W., Kvistborg, P., Schumacher, T., Haanen, J.B.A.G. and Jorritsma, A.
Human Gene Therapy Methods 25
(5): 277-287.
October 2014
HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M., Yu, Y., Liang, L., Vuralli, D., Froehler, S., Kuehnen, P., Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J., Jia, S., Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7
(5): e602.
May 2019
The zinc finger antiviral protein ZAP restricts human cytomegalovirus and selectively binds and destabilizes viral UL4/UL5 transcripts.
Gonzalez-Perez, A.C., Stempel, M., Wyler, E., Urban, C., Piras, A., Hennig, T., Ganskih, S., Wei, Y., Heim, A., Landthaler, M., Pichlmair, A., Dölken, L., Munschauer, M., Erhard, F. and Brinkmann, M.M.
mBio 12
(3): e02683-20.
4 May 2021
Modulation of RNA polymerase assembly dynamics in transcriptional regulation.
Gorski, S.A., Snyder, S.K., John, S., Grummt, I. and Misteli, T.
Molecular Cell 30
(4): 486-497.
23 May 2008
Portable biomedical devices: a critical issue during telecare services design.
Gortzis, L.G., Bakettas, I., Makropoulos, C., Graschew, G. and Nikiforidis, G.
Informatics for Health and Social Care 33
(2): 91-98.
June 2008
Collaborative work during interventional radiological procedures based on a multicast satellite-terrestrial network.
Gortzis, L.G., Papadopoulos, H., Roelofs, T.A., Rakowsky, S., Karnabatidis, D., Siablis, D., Makropoulos, C., Nikiforidis, G. and Graschew, G.
IEEE Transactions on Information Technology in Biomedicine 11
(5): 597-599.
September 2007
Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells.
Gossen, M. and Bujard, H.
Nucleic Acids Research 21
(18): 4411-4412.
11 September 1993
RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.
Gottlieb, A., Althoff, K., Grunewald, L., Thor, T., Odersky, A., Schulte, M., Deubzer, H.E., Heukamp, L., Eggert, A., Schramm, A., Schulte, J.H. and Künkele, A.
Oncotarget 8
(17): 27882-27891.
25 April 2017
Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
Gottwein, E., Corcoran, D.L., Mukherjee, N., Skalsky, R.L., Hafner, M., Nusbaum, J.D., Shamulailatpam, P., Love, C.L., Dave, S.S., Tuschl, T., Ohler, U. and Cullen, B.R.
Cell Host & Microbe 10
(5): 515-526.
17 November 2011
A viral microRNA functions as an orthologue of cellular miR-155.
Gottwein, E., Mukherjee, N., Sachse, C., Frenzel, C., Majoros, W.H., Chi, J.T.A., Braich, R., Manoharan, M., Soutschek, J., Ohler, U. and Cullen, B.R.
Nature 450
(7172): 1096-1099.
13 December 2007
MLL1 is required for maintenance of intestinal stem cells.
Goveas, N., Waskow, C., Arndt, K., Heuberger, J., Zhang, Q., Alexopoulou, D., Dahl, A., Birchmeier, W., Anastassiadis, K., Stewart, A.F. and Kranz, A.
PLoS Genetics 17
(12): e1009250.
3 December 2021
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Gozdecka, M., Meduri, E., Mazan, M., Tzelepis, K., Dudek, M., Knights, A.J., Pardo, M., Yu, L., Choudhary, J.S., Metzakopian, E., Iyer, V., Yun, H., Park, N., Varela, I., Bautista, R., Collord, G., Dovey, O., Garyfallos, D.A., De Braekeleer, E., Kondo, S., Cooper, J., Göttgens, B., Bullinger, L., Northcott, P.A., Adams, D., Vassiliou, G.S. and Huntly, B.J.P.
Nature Genetics 50
(6): 883-894.
June 2018
Prognostic value of multimarker analysis in stage III colorectal cancer: one step forward towards an individualized therapy decision.
Grabowski, P., Maaser, K., Hanski, C., Stein, H., Sturm, I., Hopfenmueller, W., Doerken, B., Buhr, H.J., Zeitz, M. and Scheruebl, H.
Onkologie 28
(8-9): 399-403.
1 August 2005
Analysis of neuroendocrine differentiation and the p53/BAX pathway in UICC stage III colorectal carcinoma identifies patients with good prognosis.
Grabowski, P., Sturm, I., Schelwies, K., Maaser, K., Buhr, H.J., Doerken, B., Zeitz, M., Daniel, P.T. and Scheruebl, H.
International Journal of Colorectal Disease 21
: 221-230.
April 2006
Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells.
Grabundzija, I., Wang, J., Sebe, A., Erdei, Z., Kajdi, R., Devaraj, A., Steinemann, D., Szuhai, K., Stein, U., Cantz, T., Schambach, A., Baum, C., Izsvák, Z., Sarkadi, B. and Ivics, Z.
Nucleic Acids Research 41
(3): 1829-1847.
1 February 2013
EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue.
Graeler, M.H., Bernhardt, G. and Lipp, M.
Genomics 53
(2): 164-169.
15 October 1998
The sphingosine 1-phosphate receptor S1P4regulates cell shape and motility via coupling to Gi and G12/13.
Graeler, M.H., Grosse, R., Kusch, A., Kremmer, E., Gudermann, T. and Lipp, M.
Journal of Cellular Biochemistry 89
(3): 507-519.
1 June 2003
INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model.
Graeser, R., Esser, N., Unger, H., Fichtner, I., Zhu, A., Unger, C. and Kratz, F.
Investigational New Drugs 28
(1): 14-19.
February 2010
Expression and prognostic value of hemopoietic cytokine receptors in acute myeloid leukemia (AML): implications for future therapeutical strategies.
Graf, M., Hecht, K., Reif, S., Pelka-Fleischer, R., Pfister, K. and Schmetzer, H.
European Journal of Haematology 72
(2): 89-106.
February 2004
Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk.
Graf, M., Reif, S., Hecht, K., Pelka-Fleischer, R., Pfister, K., Nuessler, V. and Schmetzer, H.
European Journal of Haematology 71
(5): 366-376.
November 2003
Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.
Graf, R., Munschauer, M., Mastrobuoni, G., Mayr, F., Heinemann, U., Kempa, S., Rajewsky, N. and Landthaler, M.
RNA Biology 10
(7): 1146-1159.
1 July 2013
Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.
Graf, L., Dick, A., Sendker, F., Barth, E., Marz, M., Daumke, O. and Kochs, G.
Journal of Biological Chemistry 293
(9): 3056-3072.
2 March 2018
sgRNA sequence motifs blocking efficient CRISPR/Cas9-mediated gene editing.
Graf, R., Li, X., Chu, V.T. and Rajewsky, K.
Cell Reports 26
(5): 1098-1103.
29 January 2019
BCR-dependent lineage plasticity in mature B cells.
Graf, R., Seagal, J., Otipoby, K.L., Lam, K.P., Ayoub, S., Zhang, B., Sander, S., Chu, V.T. and Rajewsky, K.
Science 363
(6428): 748-753.
15 February 2019
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Grajales-Reyes, G.E., Iwata, A., Albring, J., Wu, X., Tussiwand, R., Kc, W., Kretzer, N.M., Briseno, C.G., Durai, V., Bagadia, P., Haldar, M., Schoenheit, J., Rosenbauer, F., Murphy, T.L. and Murphy, K.M.
Nature Immunology 16
(7): 708-717.
July 2015
Telemedicine in 20 years of CARS.
Graschew, G., Rakowsky, S., Roelofs, T.A. and Schlag, P.M.
International Congress Series 1281
: 175-179.
1 May 2005
Engineering for health in OP 2000.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
IFMBE Proceedings 22
: 871-874.
2008
Medical GRID and E-learning in the virtual hospital.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
IFMBE Proceedings 20
: 413-416.
2008
Network design for telemedicine - e-health using satellite technology.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
Studies in Health Technology and Informatics 131
: 67-82.
2008
Digital medicine in the virtual hospital of the future.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
International Journal of Computer Assisted Radiology and Surgery 1 (Suppl 7)
: 119-121.
June 2006
Interactive telemedical applications in OP 2000 via satellite.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
Biomedizinische Technik 47
(S1 Pt 1): 330-333.
2002
Telemedical applications and Grid technology.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Albayrak, S. and Kaiser, S.
1 January 2005
New trends in the virtualization of hospitals - tools for global e-Health.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Heinzlreiter, P., Kranzlmueller, D. and Volkert, J.
Studies in Health Technology and Informatics 121
: 168-175.
2006
Virtual hospital and digital medicine - Why is the GRID needed?
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Heinzlreiter, P., Kranzlmueller, D. and Volkert, J.
Studies in Health Technology and Informatics 120
: 295-304.
2006
VEMH - Virtual Euro-Mediterranean Hospital for global healthcare.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Kaiser, S. and Albayrak, S.
Studies in Health Technology and Informatics 114
: 39-45.
1 January 2005
DELTASS - Disaster emergency logistic telemedicine advanced satellites system: Telemedical services for disaster emergencies.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Lieber, A., Muller, U., Czymek, R. and Dusel, W.
International Journal of Risk Assessment and Management 9
(4): 351-366.
2008
Improved tumour response by laser light treatment.
Graschew, G., Smith, J., Rakowsky, S., Roelofs, T.A., Schlag, P.M. and Stein, U.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE 6991
: 69911A.
2 May 2008
The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S., Cabantog, A., MacPhee, L., Im, J., Ruess, C., Demir, B., Sperb, N., Rücker, F.G., Döhner, K., Herold, T., Pollack, J.R., Bullinger, L., Rouhi, A. and Kuchenbauer, F.
Haematologica 107
(8): 1758-1772.
August 2022
Personalizing precision medicine: Patients with AML perceptions about treatment decisions.
Grauman, A., Kontro, M., Haller, K., Nier, S., Aakko, S., Lang, K., Zingaretti, C., Meggiolaro, E., De Padova, S., Marconi, G., Martinelli, G., Heckman, C.A., Simonetti, G., Bullinger, L. and Kihlbom, U.
Patient Education and Counseling 115
: 107883.
5 July 2023
Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level.
Graupner, V., Alexander, E., Overkamp, T., Rothfuss, O., De Laurenzi, V., Gillissen, B.F., Daniel, P.T., Schulze-Osthoff, K. and Essmann, F.
Cell Death and Differentiation 18
(7): 1130-1139.
July 2011
Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP.
Gray, E.J., Petsalaki, E., James, D.A., Bagshaw, R.D., Stacey, M.M., Rocks, O., Gingras, A.C. and Pawson, T.
Journal of Biological Chemistry 289
(51): 35397-35408.
19 December 2014
CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.
Greensmith, R., Lape, I.T., Riella, C.V., Schubert, A.J., Metzger, J.J., Dighe, A.S., Tan, X., Hemmer, B., Rau, J., Wendlinger, S., Diederich, N., Schütz, A., Riella, L.V. and Kaminski, M.M.
EMBO Molecular Medicine 16
(10): 2619-2637.
14 October 2024
MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells.
Gregersen, L.H., Jacobsen, A., Frankel, L.B., Wen, J., Krogh, A. and Lund, A.H.
BMC Cancer 12
: 232.
12 June 2012
Survivin’ acute myeloid leukaemia - a personalised target for inv(16) patients.
Greiner, J., Brown, E., Bullinger, L., Hills, R.K., Morris, V., Döhner, H., Mills, K.I. and Guinn, B.A.
International Journal of Molecular Sciences 22
(19): 10482.
1 October 2021
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.
Greiner, J., Götz, M., Hofmann, S., Schrezenmeier, H., Wiesneth, M., Bullinger, L., Döhner, H. and Schneider, V.
Cancer Immunology Immunotherapy 69
(4): 629-640.
April 2020
Ensuring center quality, proper patient selection and fair access to chimeric antigen receptor T-cell therapy: position statement of the Austrian CAR-T Cell Network.
Greinix, H.T., Attarbaschi, A., Girschikofsky, M., Greil, R., Holter, W., Neumeister, P., Peters, C., Petzer, A., Rudzki, J., Schlenke, P., Schmitt, C.A., Schwinger, W., Wolf, D., Worel, N. and Jaeger, U.
memo: Magazine of European Medical Oncology 13
(1): 27-31.
March 2020
Markers of tumour angiogenesis and tumour cells in bone marrow in gastric cancer patients.
Gretschel, S., Astrosini, C.h., Vieth, M., Joens, T., Tomov, T., Hoecker, M., Schlag, P.M. and Kemmner, W.
European Journal of Surgical Oncology 34
(6): 642-647.
June 2008
Efficacy of Different Technical Procedures for Sentinel Lymph Node Biopsy in Gastric Cancer Staging.
Gretschel, S., Bembenek, A., Huenerbein, M., Dresel, S., Schneider, W. and Schlag, P.M.
Annals of Surgical Oncology 14
(7): 2028-2035.
July 2007
Prediction of gastric cancer lymph node status by sentinel lymph node biopsy and the Maruyama computer model.
Gretschel, S., Bembenek, A., Ulmer, C., Huenerbein, M., Markwardt, J., Schneider, U. and Schlag, P.M.
European Journal of Surgical Oncology 31
: 393-400.
1 January 2005
Lymphatic mapping und Sentinel-Lymphknotendiagnostik beim Magenkarzinom [Lymphatic mapping and sentinel lymph node biopsy in gastric cancer].
Gretschel, S., Bembenek, A., Ulmer, C., Huenerbein, M., Markwardt, J., Schneider, U. and Schlag, P.M.
Chirurg 74
(2): 132-138.
February 2003
Body mass index does not affect systematic D2 lymph node dissection and postoperative morbidity in gastric cancer patients.
Gretschel, S., Christoph, F., Bembenek, A., Estevez-Schwarz, L., Schneider, U. and Schlag, P.M.
Annals of Surgical Oncology 10
(4): 363-368.
May 2003
Gastric cancer surgery in elderly patients.
Gretschel, S., Estevez-Schwarz, L., Huenerbein, M., Schneider, U. and Schlag, P.M.
World Journal of Surgery 30
: 1468-1474.
August 2006
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Gretschel, S., Haensch, W., Schlag, P.M. and Kemmner, W.
Oncology 65
(2): 139-145.
2003
Prognostic value of cytokeratin-positive bone marrow cells of gastric cancer patients.
Gretschel, S., Schick, C., Schneider, U., Estevez-Schwarz, L., Bembenek, A. and Schlag, P.M.
Annals of Surgical Oncology 14
: 373-380.
February 2007
Current status of sentinel lymph node biopsy in adenocarcinoma of the distal esophagus, gastric cardia, and proximal stomach.
Gretschel, S. and Schlag, P.M.
Recent Results in Cancer Research 182
: 107-114.
2010
Multiviszerale Resektion als Baustein eines multimodalen Behandlungskonzepts beim lokal fortgeschrittenen oder peritoneal metastasierten Magenkarzinom
[Multivisceral resection as part of a multimodal treatment concept in locally progressed or peritoneally metastasized gastric cancer].
Gretschel, S. and Schlag, P.M.
Chirurgische Gastroenterologie 23
(4): 353-359.
December 2007
Surgical strategies for gastric cancer with synchronous peritoneal carcinomatosis.
Gretschel, S., Siegel, R., Estevez-Schwarz, L., Huenerbein, M., Schneider, U. and Schlag, P.M.
British Journal of Surgery 93
(12): 1530-1535.
December 2006
Lymphatic mapping and sentinel lymph node biopsy in epidermoid carcinoma of the anal canal.
Gretschel, S., Warnick, P., Bembenek, A., Dresel, S., Koswig, S., String, A., Huenerbein, M. and Schlag, P.M.
European Journal of Surgical Oncology 34
(8): 890-894.
August 2008
Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology.
Gries, J., Schumacher, D., Arand, J., Lutsik, P., Markelova, M.R., Fichtner, I., Walter, J., Sers, C. and Tierling, S.
Epigenetics 8
(7): 765-771.
July 2013
Morphological analysis and differentiation of benign cystic neoplasms of the pancreas using computed tomography and magnetic resonance imaging.
Grieser, C., Heine, G., Stelter, L., Steffen, I.G., Rothe, J.H., Walter, T.C., Fischer, C., Bahra, M. and Denecke, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 185
(3): 219-227.
March 2013
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
Griger, J., Widholz, S.A., Jesinghaus, M., de Andrade Krätzig, N., Lange, S., Engleitner, T., Montero, J.J., Zhigalova, E., Öllinger, R., Suresh, V., Winkler, W., Lier, S., Baranov, O., Trozzo, R., Ben Khaled, N., Chakraborty, S., Yu, J., Konukiewitz, B., Steiger, K., Pfarr, N., Rajput, A., Sailer, D., Keller, G., Schirmacher, P., Röcken, C., Fagerstedt, K.W., Mayerle, J., Schmidt-Supprian, M., Schneider, G., Weichert, W., Calado, D.P., Sommermann, T., Klöppel, G., Rajewsky, K., Saur, D. and Rad, R.
Cancer Cell 41
(7): 1327-1344.e10.
10 July 2023
Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T., Stein, S., Qi, J., Wende, H., Garratt, A.N., Nave, K.A., Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110
(45): 18174-18179.
5 November 2013
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells.
Grimes, K., Jeong, H., Amoah, A., Xu, N., Niemann, J., Raeder, B., Hasenfeld, P., Stober, C., Rausch, T., Benito, E., Jann, J.C., Nowak, D., Emini, R., Hoenicka, M., Liebold, A., Ho, A., Shuai, S., Geiger, H., Sanders, A.D. and Korbel, J.O.
Nature Genetics 56
(6): 1134-1146.
June 2024
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
Grimm, J., Sachs, M., Britsch, S., Di Cesare, S., Schwarz-Romond, T. and Birchmeier, W.
Journal of Cell Biology 154
(2): 345-354.
23 July 2001
The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat, J., Heuberger, J., Vidal, R., Goveas, N., Kosel, F., Berenguer-Llergo, A., Kranz, A., Wulf-Goldenberg, A., Behrens, D., Melcher, B., Sauer, S., Vieth, M., Batlle, E., Stewart, A. and Birchmeier, W.
Nature Communications 11
(1): 6422.
21 December 2020
Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.
Grinat, J., Kosel, F., Goveas, N., Kranz, A., Alexopoulou, D., Rajewsky, K., Sigal, M., Stewart, A.F. and Heuberger, J.
Life Science Alliance 5
(4): e202101187.
April 2022
Cell cycle-controlled interaction of nucleolin with the retinoblastoma protein and cancerous cell transformation.
Grinstein, E., Shan, Y., Karawajew, L., Snijders, P.J., Meijer, C.J., Royer, H.D. and Wernet, P.
Journal of Biological Chemistry 281
(31): 22223-22235.
4 August 2006
Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancer.
Grinstein, E., Wernet, P., Snijders, P.J.F., Rosl, F., Weinert, I., Jia, W.T., Kraft, R., Schewe, C., Schwabe, M., Hauptmann, S., Dietel, M., Meijer, C.J.L.M. and Royer, H.D.
Journal of Experimental Medicine 196
(8): 1067-1078.
21 October 2002
Mechanism of virus attenuation by codon pair deoptimization.
Groenke, N., Trimpert, J., Merz, S., Conradie, A.M., Wyler, E., Zhang, H., Hazapis, O.G., Rausch, S., Landthaler, M., Osterrieder, N. and Kunec, D.
Cell Reports 31
(4): 107586.
28 April 2020
A multichannel time-domain scanning fluorescence mammograph: Performance assessment and first in vivo results.
Grosenick, D., Hagen, A., Steinkellner, O., Poellinger, A., Burock, S., Schlag, P.M., Rinneberg, H. and Macdonald, R.
Review of Scientific Instruments 82
(2): 1024302.
February 2011
Evaluation of higher-order time-domain perturbation theory of photon diffusion on breast-equivalent phantoms and optical mammograms.
Grosenick, D., Kummrow, A., Macdonald, R., Schlag, P.M. and Rinneberg, H.
Physical Review E 76
(6 Pt 1): 061908.
December 2007
Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients.
Grosenick, D., Moesta, K.T., Moeller, M., Mucke, J., Wabnitz, H., Gebauer, B., Stroszczynski, C., Wassermann, B., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 50
: 2429-2449.
1 January 2005
Time-domain optical mammography: initial clinical results on detection and characterization of breast tumors.
Grosenick, D., Moesta, K.T., Wabnitz, H., Mucke, J., Stroszczynski, C., Macdonald, R., Schlag, P.M. and Rinneberg, H.
Applied Optics 42
(16): 3170-3186.
1 June 2003
Concentration and oxygen saturation of haemoglobin of 50 breast tumours determined by time-domain optical mammography.
Grosenick, D., Wabnitz, H., Moesta, K.T., Mucke, J., Moeller, M., Stroszczynski, C., Stoessel, J., Wassermann, B., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 49
(7): 1165-1181.
18 March 2004
Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas.
Grosenick, D., Wabnitz, H., Moesta, K.T., Mucke, J., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 50
: 2451-2468.
1 January 2005
Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit.
Grosheva, A.S., Zharkov, D.O., Stahl, J., Gopanenko, Al.V., Tupikin, A.E., Kabilov, M.R., Graifer, D.M. and Karpova, G.G.
Nucleic Acids Research 45
(7): 3833-3843.
20 April 2017
Therapy-related AML: long-term outcome in a large cohort of AML-patients with intensive and non-intensive therapy.
Gross, S., Ihlow, J., Busack, L., Adamiak, K., Schrezenmeier, J., Jesse, J., Schwarz, M., Flörcken, A., Vuong, L.G., Rieger, K., Krönke, J., le Coutre, P., Boldt, V., von Brünneck, A.C., Horst, D., Burmeister, T., Blau, I.W., Keller, U., Bullinger, L. and Westermann, J.
Blood Cancer Journal 14
(1): 160.
16 September 2024
Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S., Eckert, C., Arkona, C., Radetzki, S., Böhm, K., Heinemann, U., Wolber, G., von Kries, J.P., Birchmeier, W. and Rademann, J.
ChemMedChem 10
(5): 815-826.
May 2015
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
Grossmann, K.S., Grund, C., Huelsken, J., Behrend, M., Erdmann, B., Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 167
(1): 149-160.
11 October 2004
The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H., Paul, F.E., Cheret, C., Garratt, A.N., Zurborg, S., Feinberg, K., Besser, D., Schulz, H., Peles, E., Selbach, M., Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106
(39): 16704-16709.
29 September 2009
Emotional voice processing: investigating the role of genetic variation in the serotonin transporter across development.
Grossmann, T., Vaish, A., Franz, J., Schroeder, R., Stoneking, M. and Friederici, A.D.
PLoS ONE 8
(7): e68377.
8 July 2013
Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.
Grosswendt, S., Filipchyk, A., Manzano, M., Klironomos, F., Schilling, M., Herzog, M., Gottwein, E. and Rajewsky, N.
Molecular Cell 54
(6): 1042-1054.
19 June 2014
Epigenetic regulator function through mouse gastrulation.
Grosswendt, S., Kretzmer, H., Smith, Z.D., Kumar, A.S., Hetzel, S., Wittler, L., Klages, S., Timmermann, B., Mukherji, S. and Meissner, A.
Nature 584
(7819): 102-108.
6 August 2020
Ectopic expression of E2F1 stimulates beta cell proliferation and function.
Grouwels, G., Cai, Y., Hoebeke, I., Leuckx, G., Heremans, Y., Ziebold, U., Stange, G., Chintinne, M., Ling, Z., Pipeleers, D., Heimberg, H. and Van de Casteele, M.
Diabetes 59
(6): 1435-1444.
June 2010
T-cell-mediated lysis of B cells induced by a CD19xCD3 bispecific single-chain antibody is perforin dependent and death receptor independent.
Gruen, M., Bommert, K. and Bargou, R.C.
Cancer Immunology Immunotherapy 53
(7): 625-632.
1 January 2004
Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay.
Gruetzmann, R., Molnar, B., Pilarsky, C., Habermann, J.K., Schlag, P.M., Saeger, H.D., Miehlke, S., Stolz, T., Model, F., Roblick, U.J., Bruch, H.P., Koch, R., Liebenberg, V., Devos, T., Song, X., Day, R.H., Sledziewski, A.Z. and Lofton-Day, C.
PLoS ONE 3
(11): e3759.
19 November 2008
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy.
Grunewald, L., Andersch, L., Helmsauer, K., Schwiebert, S., Klaus, A., Henssen, A.G., Straka, T., Lodrini, M., Wicha, S.G., Fuchs, S., Hertwig, F., Westermann, F., Vitali, A., Caramel, C., Büchel, G., Eilers, M., Astrahantseff, K., Eggert, A., Höpken, U.E., Schulte, J.H., Blankenstein, T., Anders, K. and Künkele, A.
Pharmacological Research
: 107608.
17 January 2025
(In Press)
A reproducible bioprinted 3D tumor model serves as a preselection tool for CAR T cell therapy optimization.
Grunewald, L., Lam, T., Andersch, L., Klaus, A., Schwiebert, S., Winkler, A., Gauert, A., Heeren-Hagemann, A.I., Astrahantseff, K., Klironomos, F., Thomas, A., Deubzer, H.E., Henssen, A.G., Eggert, A., Schulte, J.H., Anders, K., Kloke, L. and Künkele, A.
Frontiers in Immunology 12
: 689697.
29 June 2021
Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Grunwald, S., Hopf, L.V.M., Bock-Bierbaum, T., Lally, C.C.M., Spahn, C.M.T. and Daumke, O.
Nature Communications 11
(1): 5506.
2 November 2020
Recombination between heterologous human acrocentric chromosomes.
Guarracino, A., Buonaiuto, S., de Lima, L.G., Potapova, T., Rhie, A., Koren, S., Rubinstein, B., Fischer, C., Gerton, J.L., Phillippy, A.M., Colonna, V. and Garrison, E.
Nature 617
(7960): 335-343.
11 May 2023
Inefficient CAR-proximal signaling blunts antigen sensitivity.
Gudipati, V., Rydzek, J., Doel-Perez, I., Gonçalves, V.D.R., Scharf, L., Königsberger, S., Lobner, E., Kunert, R., Einsele, H., Stockinger, H., Hudecek, M. and Huppa, J.B.
Nature Immunology 21
(8): 848-856.
August 2020
Bio++: efficient extensible libraries and tools for computational molecular evolution.
Gueguen, L., Gaillard, S., Boussau, B., Gouy, M., Groussin, M., Rochette, N.C., Bigot, T., Fournier, D., Pouyet, F., Cahais, V., Bernard, A., Scornavacca, C., Nabholz, B., Haudry, A., Dachary, L., Galtier, N., Belkhir, K. and Dutheil, J.Y.
Molecular Biology and Evolution 30
(8): 1745-1750.
August 2013
Disruption of cell death signaling in cancer: impact on disease prognosis and response to therapy.
Guener, D., Belka, C. and Daniel, P.T.
Current Medicinal Chemistry Anti-Cancer Agents 3
(5): 319-326.
1 September 2003
Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.
Guener, D., Sturm, I., Hemmati, P., Hermann, S., Hauptmann, S., Wurm, R., Budach, V., Doerken, B., Lorenz, M. and Daniel, P.T.
International Journal of Cancer 103
(4): 445-454.
10 February 2003
Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Guenther, S., Schlundt, A., Sticht, J., Roske, Y., Heinemann, U., Wiesmueller, K.H., Jung, G., Falk, K., Roetzschke, O. and Freund, C.
Proceedings of the National Academy of Sciences of the United States of America 107
(51): 22219-22224.
21 December 2010
Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease.
Guenther, U.P., Handoko, L., Varon, R., Stephani, U., Tsao, C.Y., Mendell, J.R., Lützkendorf, S., Hübner, C., von Au, K., Jablonka, S., Dittmar, G., Heinemann, U., Schuetz, A. and Schuelke, M.
Journal of Molecular Medicine 87
(1): 31-41.
January 2009
Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis.
Guenthert, U., Schwaerzler, C., Wittig, B., Laman, J., Ruiz, P., Stauder, R., Bloem, A., Smadja-Joffe, F., Zoeller, M. and Rolink, A.
Advances in Experimental Medicine and Biology 451
: 43-49.
1998
Human peripheral blood and bone marrow Epstein-Barr virus-specific T-cell repertoire in latent infection reveals distinct memory T-cell subsets.
Guerreiro, M., Na, I.K., Letsch, A., Haase, D., Bauer, S., Meisel, C., Roemhild, A., Reinke, P., Volk, H.D. and Scheibenbogen, C.
European Journal of Immunology 40
(6): 1566-1576.
June 2010
Interdisziplinaere Tumorkonferenzen : regionale und ueberregionale telemedizinische und teleradiologische Anbindung von Tumorzentren [Interdisciplinary tumor boards : regional and supraregional telemedical and teleradiological links to tumor boards].
Guettler, F.V., Rakowsky, S., Nagel, S.N., Teichgraeber, U. and Schlag, P.M.
Onkologe 18
(5): 389-397.
May 2012
Technical considerations for the use of CRISPR/Cas9 in hematology research.
Gundry, M.C., Dever, D.P., Yudovich, D., Bauer, D.E., Haas, S., Wilkinson, A.C. and Singbrant, S.
Experimental Hematology 54
: 4-11.
October 2017
How to find genomic regions relevant for gene regulation.
Guo, X., Ohler, U. and Yildirim, F.
Medizinische Genetik 33
(2): 157-165.
14 August 2021
Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.
Gupta, S., Hoepner, S., Rupp, B., Guenther, S., Dickhaut, K., Agarwal, N., Cardoso, M.C., Kuehne, R., Wiesmueller, K.H., Jung, G., Falk, K. and Roetzschke, O.
PLoS ONE 3
(3): e1814.
19 March 2008
RNA-containing adenovirus/polyethylenimine transfer complexes effectively transduce dendritic cells and induce antigen-specific T cell responses.
Gust, T.C., Diebold, S.S., Cotten, M. and Zenke, M.
Journal of Gene Medicine 6
(4): 464-470.
1 April 2004
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.
Guy, C.S., Vignali, K.M., Temirov, J., Bettini, M.L., Overacre, A.E., Smeltzer, M., Zhang, H., Huppa, J.B., Tsai, Y.H., Lobry, C., Xie, J., Dempsey, P.J., Crawford, H.C., Aifantis, I., Davis, M.M. and Vignali, D.A.A.
Nature Immunology 14
(3): 262-70.
March 2013
Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.
Gyoerffy, B., Serra, V., Juerchott, K., Abdul-Ghani, R., Garber, M., Stein, U., Petersen, I., Lage, H., Dietel, M. and Schaefer, R.
Oncogene 24
(15): 7542-7551.
25 July 2005
Splenic marginal zone granulocytes acquire an accentuated neutrophil B cell-helper phenotype in chronic lymphocytic leukemia.
Gätjen, M., Brand, F., Grau, M., Gerlach, K., Kettritz, R., Westermann, J., Anagnostopoulos, I., Lenz, P., Lenz, G., Höpken, U.E. and Rehm, A.
Cancer Research 76
(18): 5253-5265.
15 September 2016
Placental growth factor promotes neural invasion and predicts disease prognosis in resectable pancreatic cancer.
Göhrig, A., Hilfenhaus, G., Rosseck, F., Welzel, M., Moser, B., Barbone, G., Kunze, C.A., Rein, J., Wilken, G., Böhmig, M., Malinka, T., Tacke, F., Bahra, M., Detjen, K.M. and Fischer, C.
Journal of Experimental & Clinical Cancer Research 43
(1): 153.
30 May 2024
Temporal analysis of T-cell receptor-imposed forces via quantitative single molecule FRET measurements.
Göhring, J., Kellner, F., Schrangl, L., Platzer, R., Klotzsch, E., Stockinger, H., Huppa, J.B. and Schütz, G.J.
Nature Communications 12
(1): 2502.
4 May 2021
Generation of a human induced pluripotent stem cell line (BIHi292-A) from PBMCs of a female patient diagnosed with Nasu-Hakola disease (NHD)/ Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy (PLOSL) carrying a novel heterozygous mutation in the TREM2 gene.
Göttert, R., Vallone, V.F., Stachelscheid, H., Metzger, J.J., Caedo, C.C., Buthut, M., Prüss, H., Endres, M., Schilling, S. and Gertz, K.
Stem Cell Research
: 103660.
15 January 2025
AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Götz, F., Roske, Y., Schulz, M.S., Autenrieth, K., Bertinetti, D., Faelber, K., Zühlke, K., Kreuchwig, A., Kennedy, E., Krause, G., Daumke, O., Herberg, F.W., Heinemann, U. and Klussmann, E.
Biochemical Journal 473
(13): 1881-1894.
28 June 2016
Saffron crudes and compounds restrict MACC1-dependent cell proliferation and migration of colorectal cancer cells.
Güllü, N., Kobelt, D., Brim, H., Rahman, S., Timm, L., Smith, J., Soleimani, A., Di Marco, S., Bisti, S., Ashktorab, H. and Stein, U.
Cells 9
(8): 1829.
3 August 2020
MACC1-dependent antitumor effect of curcumin in colorectal cancer.
Güllü, N., Smith, J., Herrmann, P. and Stein, U.
Nutrients 14
(22): 4792.
12 November 2022
A molecularly characterized preclinical platform of subcutaneous renal cell carcinoma (RCC) patient-derived xenograft models to evaluate novel treatment strategies.
Gürgen, D., Becker, M., Dahlmann, M., Flechsig, S., Schaeffeler, E., Büttner, F.A., Schmees, C., Bohnert, R., Bedke, J., Schwab, M., Wendler, J.J., Schostak, M., Jandrig, B., Walther, W. and Hoffmann, J.
Frontiers in Oncology 12
: 889789.
21 June 2022
Constitutive monocyte-restricted activity of NF-M, a nuclear factor that binds to a C/EBP motif.
Haas, J.G., Stroebel, M., Leutz, A., Wendelgass, P., Mueller, C., Sterneck, E., Riethmueller, G. and Ziegler-Heitbrock, H.W.
Journal of Immunology 149
(1): 237-243.
1 July 1992
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors.
Haas, S., Hansson, J., Klimmeck, D., Loeffler, D., Velten, L., Uckelmann, H., Wurzer, S., Prendergast, Á.M., Schnell, A., Hexel, K., Santarella-Mellwig, R., Blaszkiewicz, S., Kuck, A., Geiger, H., Milsom, M.D., Steinmetz, L.M., Schroeder, T., Trumpp, A., Krijgsveld, J. and Essers, M.A.G.
Cell Stem Cell 17
(4): 422-34.
1 October 2015
Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway.
Habermehl, D., Kammerer, B., Handrick, R., Eldh, T., Gruber, C., Cordes, N., Daniel, P.T., Plasswilm, L., Bamberg, M., Belka, C. and Jendrossek, V.
BMC Cancer 6
: 14.
17 January 2006
A prospective observational study of real-world treatment and outcome in secondary CNS lymphoma.
Habringer, S., Demel, U.M., Fietz, A.K., Lammer, F., Schroers, R., Hofer, S., Bairey, O., Braess, J., Meier-Stiegen, A.S., Stuhlmann, R., Schmidt-Hieber, M., Hoffmann, J., Zinngrebe, B., Kaiser, U., Reimer, P., Möhle, R., Fix, P., Höffkes, H.G., Langenkamp, U., Büschenfelde, C.M.Z., Hopfer, O., Stoltefuß, A., La Rosée, P., Blasberg, H., Jordan, K., Kaun, S., Meurer, A., Unteroberdörster, M., von Brünneck, A.C., Capper, D., Heppner, F.L., Chapuy, B., Janz, M., Schwartz, S., Konietschke, F., Vajkoczy, P., Korfel, A. and Keller, U.
European Journal of Cancer 196
: 113436.
January 2024
A diagnostic challenge of KIT p.V559D and BRAF p.G469A mutations in a paragastric mass.
Habringer, S., Ihlow, J., Kleo, K., Klostermann, A., Schmidt, M., Chai, L., Knödler, M., Leyvraz, S., Sigler, C., Sinn, B., Maschmeyer, G., Jegodka, Y., Benary, M., Ott, C.E., Tinhofer, I., Schäfer, R., Möbs, M., Keller, U., Keilholz, U. and Rieke, D.T.
Oncologist 29
(10): 908-912.
October 2024
Regulated intramembrane proteolysis and degradation of murine epithelial cell adhesion molecule mEpCAM.
Hachmeister, M., Bobowski, K.D., Hogl, S., Dislich, B., Fukumori, A., Eggert, C., Mack, B., Kremling, H., Sarrach, S., Coscia, F., Zimmermann, W., Steiner, H., Lichtenthaler, S.F. and Gires, O.
PLoS ONE 8
(8): e71836.
29 August 2013
Transcriptional profiling identifies Id2 function in dendritic cell development.
Hacker, C., Kirsch, R.D., Ju, X.S., Hieronymus, T., Gust, T.C., Kuhl, C., Jorgas, T., Kurz, S.M., Rose-John, S., Yokota, Y. and Zenke, M.
Nature Immunology 4
(4): 380-386.
April 2003
Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Hadjihannas, M.V., Brueckner, M., Jerchow, B., Birchmeier, W., Dietmaier, W. and Behrens, J.
Proceedings of the National Academy of Sciences of the United States of America 103
(28): 10747-10752.
11 July 2006
Hand grip strength in patients with advanced cancer: a prospective study.
Hadzibegovic, S., Porthun, J., Lena, A., Weinlaänder, P., Lück, L.C., Potthoff, S.K., Rösnick, L., Fröhlich, A.K., Ramer, L.V., Sonntag, F., Wilkenshoff, U., Ahn, J., Keller, U., Bullinger, L., Mahabadi, A.A., Totzeck, M., Rassaf, T., von Haehling, S., Coats, A.J.S., Anker, S.D., Roeland, E.J., Landmesser, U. and Anker, M.S.
Journal of Cachexia Sarcopenia and Muscle 14
(4): 1682-1694.
August 2023
Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.
Haeaerae, O., Fujimori, S., Schmidt-Ullrich, R., Hartmann, C., Thesleff, I. and Mikkola, M.L.
Development 138
(13): 2681-2691.
July 2011
Alterations of pre-mRNA splicing in human inflammatory bowel disease.
Haesler, R., Kerick, M., Mah, N., Hultschig, C., Richter, G., Bretz, F., Sina, C., Lehrach, H., Nietfeld, W., Schreiber, S. and Rosenstiel, P.
European Journal of Cell Biology 90
(6-7): 603-611.
June 2011
Morphologic dysplasia in de novo acute myeloid leukemia (AML) is related to unfavorable cytogenetics but has no independent prognostic relevance under the conditions of intensive induction therapy: results of a multiparameter analysis from the German AML Cooperative Group studies.
Haferlach, T., Schoch, C., Loeffler, H., Gassmann, W., Kern, W., Schnittger, S., Fonatsch, C., Ludwig, W.D., Wuchter, C., Schlegelberger, B., Staib, P., Reichle, A., Kubica, U., Eimermacher, H., Balleisen, L., Grueneisen, A., Haase, D., Aul, C., Karow, J., Lengfelder, E., Woermann, B., Heinecke, A., Sauerland, M.C., Buechner, T. and Hiddemann, W.
Journal of Clinical Oncology 21
: 256-265.
15 January 2003
McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.
Hafez, D., Karabacak, A., Krueger, S., Hwang, Y.C., Wang, L.S., Zinzen, R.P. and Ohler, U.
Genome Biology 18
(1): 199.
26 October 2017
Transcription factor induction of vascular blood stem cell niches in vivo.
Hagedorn, E.J., Perlin, J.R., Freeman, R.J., Wattrus, S.J., Han, T., Mao, C., Kim, J.W., Fernández-Maestre, I., Daily, M.L., D'Amato, C., Fairchild, M.J., Riquelme, R., Li, B., Ragoonanan, D.A.V.E., Enkhbayar, K., Henault, E.L., Wang, H.G., Redfield, S.E., Collins, S.H., Lichtig, A., Yang, S., Zhou, Y., Kunar, B., Gomez-Salinero, J.M., Dinh, T.T., Pan, J., Holler, K., Feldman, H.A., Butcher, E.C., van Oudenaarden, A., Rafii, S., Junker, J.P. and Zon, L.I.
Developmental Cell 58
(12): 1037-1051.
19 June 2023
Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis.
Hagemann, C., Fuchs, S., Monoranu, C.M., Herrmann, P., Smith, J., Hohmann, T., Grabiec, U., Kessler, A.F., Dehghani, F., Loehr, M., Ernestus, R.I., Vince, G.H. and Stein, U.
Neuro-Oncology 15
(12): 1696-1709.
December 2013
Circulating MACC1 transcripts in glioblastoma patients predict prognosis and treatment response.
Hagemann, C., Neuhaus, N., Dahlmann, M., Kessler, A.F., Kobelt, D., Herrmann, P., Eyrich, M., Freitag, B., Linsenmann, T., Monoranu, C.M., Ernestus, R.I., Löhr, M. and Stein, U.
Cancers 11
(6): 825.
13 June 2019
Late-fluorescence mammography assesses tumor capillary permeability and differentiates malignant from benign lesions.
Hagen, A., Grosenick, D., Macdonald, R., Rinneberg, H., Burock, S., Warnick, P., Poellinger, A. and Schlag, P.M.
Optics Express 17
(19): 17016-17033.
14 September 2009
miR-142 favors naïve B cell residence in peripheral lymph nodes.
Hagen, M., Chakraborty, T., Olson, W.J., Heitz, M., Hermann-Kleiter, N., Kimpel, J., Jenewein, B., Pertoll, J., Labi, V., Rajewsky, K. and Derudder, E.
Frontiers in Immunology 13
: 847415.
10 November 2022
Diffusion maps for high-dimensional single-cell analysis of differentiation data.
Haghverdi, L., Buettner, F. and Theis, F.J.
Bioinformatics 31
(18): 2989-2998.
15 September 2015
Diffusion pseudotime robustly reconstructs lineage branching.
Haghverdi, L., Büttner, M., Wolf, F.A., Buettner, F. and Theis, F.J.
Nature Methods 13
(10): 845-848.
October 2016
Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors.
Haghverdi, L., Lun, A.T.L., Morgan, M.D. and Marioni, J.C.
Nature Biotechnology 36
(5): 421-427.
May 2018
Crystal structure and site-directed mutagenesis of Bacillus macerans endo-1,3-1,4-beta-glucanase.
Hahn, M., Olsen, O., Politz, O., Borriss, R. and Heinemann, U.
Journal of Biological Chemistry 270
(7): 3081-3088.
17 February 1995
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M., Pablo-Tortola, C., Todiras, M., Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M., Jarosch, E., Sommer, T., Bröker, B.M., Felix, S.B., Scheidereit, C., Weber-Carstens, S., Butter, C., Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 11
(1): 103-119.
February 2020
Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines.
Hailfinger, S., Nogai, H., Pelzer, C., Jaworski, M., Cabalzar, K., Charton, J.E., Guzzardi, M., Decaillet, C., Grau, M., Doerken, B., Lenz, P., Lenz, G. and Thome, M.
Proceedings of the National Academy of Sciences of the United States of America 108
(35): 14596-14601.
30 August 2011
A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3.
Halatsch, M.E., Kast, R.E., Karpel-Massler, G., Mayer, B., Zolk, O., Schmitz, B., Scheuerle, A., Maier, L., Bullinger, L., Mayer-Steinacker, R., Schmidt, C., Zeiler, K., Elshaer, Z., Panther, P., Schmelzle, B., Hallmen, A., Dwucet, A., Siegelin, M.D., Westhoff, M.A., Beckers, K., Bouche, G. and Heiland, T.
Neuro-Oncology Advances 3
(1): vdab075.
7 August 2021
Light-induced reduction of bovine adrenodoxin via the covalently bound ruthenium(II) bipyridyl complex: Intramolecular electron transfer and crystal structure.
Halavaty, A., Mueller, J.J., Contzen, J., Jung, C., Hannemann, F., Bernhardt, R., Galander, M., Lendzian, F. and Heinemann, U.
Biochemistry 45
(3): 709-718.
24 January 2006
Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.
Halik, A., Tilgner, M., Silva, P., Estrada, N., Altwasser, R., Jahn, E., Heuser, M., Hou, H.A., Pratcorona, M., Hills, R.K., Metzeler, K.H., Fenwarth, L., Dolnik, A., Terre, C., Kopp, K., Blau, O., Szyska, M., Christen, F., Krönke, J., Vasseur, L., Löwenberg, B., Esteve, J., Valk, P.J.M., Duchmann, M., Chou, W.C., Linch, D.C., Döhner, H., Gale, R.E., Döhner, K., Bullinger, L., Yoshida, K. and Damm, F.
Journal of Hematology & Oncology 17
(1): 70.
19 August 2024
Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells.
Halvorsen, B., Dahl, T.B., Smedbakken, L.M., Singh, A., Michelsen, A.E., Skjelland, M., Krohg-Sørensen, K., Russell, D., Höpken, U.E., Lipp, M., Damås, J.K., Holm, S., Yndestad, A., Biessen, E.A. and Aukrust, P.
Cardiovascular Research 102
(1): 148-156.
1 April 2014
A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signaling.
Hamann, L., Kumpf, O., Mueller, M., Visintin, A., Eckert, J., Schlag, P.M. and Schumann, R.R.
Genes and Immunity 5
(4): 283-288.
1 June 2004
Comparative profiling of the novel epothilone, sagopilone, in xenografts derived from primary non-small cell lung cancer.
Hammer, S., Sommer, A., Fichtner, I., Becker, M., Rolff, J., Merk, J., Klar, U. and Hoffmann, J.
Clinical Cancer Research 16
(5): 1452-1465.
1 March 2010
Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice.
Hammer, K.P., Mustroph, J., Stauber, T., Birchmeier, W., Wagner, S. and Maier, L.S.
PLoS ONE 16
(6): e0252649.
4 June 2021
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.
Hammer, Q., Rückert, T., Borst, E.M., Dunst, J., Haubner, A., Durek, P., Heinrich, F., Gasparoni, G., Babic, M., Tomic, A., Pietra, G., Nienen, M., Blau, I.W., Hofmann, J., Na, I.K., Prinz, I., Koenecke, C., Hemmati, P., Babel, N., Arnold, R., Walter, J., Thurley, K., Mashreghi, M.F., Messerle, M. and Romagnani, C.
Nature Immunology 19
(5): 453-463.
May 2018
Histone deacetylase 1 controls CD4(+) T cell trafficking in autoinflammatory diseases.
Hamminger, P., Marchetti, L., Preglej, T., Platzer, R., Zhu, C., Kamnev, A., Rica, R., Stolz, V., Sandner, L., Alteneder, M., Kaba, E., Waltenberger, D., Huppa, J.B., Trauner, M., Bock, C., Lyck, R., Bauer, J., Dupré, L., Seiser, C., Boucheron, N., Engelhardt, B. and Ellmeier, W.
Journal of Autoimmunity 119
: 102610.
May 2021
Promoter crosstalk effects on gene expression.
Hampf, M. and Gossen, M.
Journal of Molecular Biology 365
(4): 911-920.
26 January 2007
A protocol for combined Photinus and Renilla luciferase quantification compatible with protein assays.
Hampf, M. and Gossen, M.
Analytical Biochemistry 356
(1): 94-99.
1 September 2006
Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
Han, Y., Lindner, S., Bei, Y., Garcia, H.D., Timme, N., Althoff, K., Odersky, A., Schramm, A., Lissat, A., Künkele, A., Deubzer, H.E., Eggert, A., Schulte, J.H. and Henssen, A.G.
Cancer Letters 445
: 24-33.
31 March 2019
Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash, A.M., Kappel, L.W., Yim, N.L., Nejat, R.A., Goldberg, G.L., Smith, O.M., Rao, U.K., Dykstra, L., Na, I.K., Holland, A.M., Dudakov, J.A., Liu, C., Murphy, G.F., Leonard, W.J., Heller, G. and van den Brink, M.R.M.
Blood 118
(2): 446-455.
14 July 2011
Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax.
Handrick, R., Ganswindt, U., Faltin, H., Goecke, B., Daniel, P.T., Budach, W., Belka, C. and Jendrossek, V.
Radiotherapy and Oncology 90
(3): 413-421.
March 2009
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
Hanna, J., Schütz, A., Zimmermann, F., Behlke, J., Sommer, T. and Heinemann, U.
Journal of Biological Chemistry 287
(11): 8633-8640.
9 March 2012
Characterization of the human P-type 6-phosphofructo-1-kinase gene promoter in neural cell lines.
Hannemann, A., Jandrig, B., Gaunitz, F., Eschrich, K. and Bigl, M.
Gene 345
(2): 237-247.
1 January 2005
The dipole moment of the electron carrier adrenodoxin is not critical for redox partner interaction and electron transfer.
Hannemann, F., Guyot, A., Zoellner, A., Mueller, J.J., Heinemann, U. and Bernhardt, R.
Journal of Inorganic Biochemistry 103
(7): 997-1004.
July 2009
A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4.
Hansen, M.T., Forst, B., Cremers, N., Quagliata, L., Ambartsumian, N., Grum-Schwensen, B., Klingelhoefer, J., Abdul-Al, A., Herrmann, P., Osterland, M., Stein, U., Nielsen, G.H., Scherer, P.E., Lukanidin, E., Sleeman, J.P. and Grigorian, M.
Oncogene 34
(4): 424-435.
22 January 2015
GOPHER: Generator Of Probes for capture Hi-C Experiments at high Resolution.
Hansen, P., Ali, S., Blau, H., Danis, D., Hecht, J., Kornak, U., Lupiáñez, D.G., Mundlos, S., Steinhaus, R. and Robinson, P.N.
BMC Genomics 20
(1): 40.
14 January 2019
Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion.
Hanssen, E., Dekiwadia, C., Riglar, D.T., Rug, M., Lemgruber, L., Cowman, A.F., Cyrklaff, M., Kudryashev, M., Frischknecht, F., Baum, J. and Ralph, S.A.
Cellular Microbiology 15
(9): 1457-1472.
September 2013
Information theoretic based segments for language identification.
Harbeck, S., Ohler, U., Noth, E. and Niemann, H.
Lecture Notes in Computer Science 1692
: 187-192.
1999
Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment.
Haremaki, T., Metzger, J.J., Rito, T., Ozair, M.Z., Etoc, F. and Brivanlou, A.H.
Nature Biotechnology 37
(10): 1198-1208.
October 2019
Comparison of the effect of orally administered soluble β-(1-3),(1-6)-D-glucan and of G-CSF on the recovery of murine hematopoiesis.
Harnack, U., Eckert, K., Fichtner, I. and Pecher, G.
In Vivo 24
(1): 59-63.
January 2010
Oral administration of a soluble 1-3, 1-6 beta-glucan during prophylactic survivin peptide vaccination diminishes growth of a B cell lymphoma in mice.
Harnack, U., Eckert, K., Fichtner, I. and Pecher, G.
International Immunopharmacology 9
(11): 1298-1303.
October 2009
Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis.
Harnack, C., Berger, H., Liu, L., Mollenkopf, H.J., Strowig, T. and Sigal, M.
Gut Microbes 15
(1): 2233689.
10 July 2023
A critical period of translational control during brain development at codon resolution.
Harnett, D., Ambrozkiewicz, M.C., Zinnall, U., Rusanova, A., Borisova, E., Drescher, A.N., Couce-Iglesias, M., Villamil, G., Dannenberg, R., Imami, K., Münster-Wandowski, A., Fauler, B., Mielke, T., Selbach, M., Landthaler, M., Spahn, C.M.T., Tarabykin, V., Ohler, U. and Kraushar, M.L.
Nature Structural & Molecular Biology 29
(12): 1277-1290.
December 2022
Genome-wide analysis of actively translated open reading frames using riboTaper/ORFquant.
Harnett, D., Meerdink, E., Calviello, L., Sydow, D. and Ohler, U.
Methods in Molecular Biology 2252
: 331-346.
2021
Mesothelial cell HIF1α expression is metabolically downregulated by metformin to prevent oncogenic tumor-stromal crosstalk.
Hart, P.C., Kenny, H.A., Grassl, N., Watters, K.M., Litchfield, L.M., Coscia, F., Blaženović, I., Ploetzky, L., Fiehn, O., Mann, M., Lengyel, E. and Romero, I.L.
Cell Reports 29
(12): 4086-4098.
17 December 2019
p53 terminates the regenerative fetal-like state after colitis-associated injury.
Hartl, K., Bayram, Ş., Wetzel, A., Harnack, C., Lin, M., Fischer, A.S., Liu, L., Beccacec, G., Mastrobuoni, G., Geisberger, S., Forbes, M., Monteiro, B.J.E., Macino, M., Flores, R.E., Engelmann, C., Mollenkopf, H.J., Schupp, M., Tacke, F., Sanders, A.D., Kempa, S., Berger, H. and Sigal, M.
Science Advances 10
(43): eadp8783.
25 October 2024
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A., Sieverling, L., Nadler-Holly, M., Ziehm, M., Toprak, U.H., Herrmann, C., Ishaque, N., Okonechnikov, K., Gartlgruber, M., Park, Y.G., Wecht, E.M., Savelyeva, L., Henrich, K.O., Rosswog, C., Fischer, M., Hero, B., Jones, D.T.W., Pfaff, E., Witt, O., Pfister, S.M., Volckmann, Ri., Koster, J., Kiesel, K., Rippe, K., Taschner-Mandl, S., Ambros, P., Brors, B., Selbach, M., Feuerbach, L. and Westermann, F.
Nature Communications 12
(1): 1269.
24 February 2021
Alternative splicing substantially diversifies the transcriptome during early photomorphogenesis and correlates with the energy availability in arabidopsis.
Hartmann, L., Drewe-Boss, P., Wiessner, T., Wagner, G., Geue, S., Lee, H.C., Obermueller, D.M., Kahles, A., Behr, J., Sinz, F.H., Raetsch, G. and Wachter, A.
Plant Cell 28
(11): 2715-2734.
November 2016
Paracrine and autocrine regulation of gene expression by Wnt-inhibitor Dickkopf in wild-type and mutant hepatocytes.
Hartung, N., Benary, U., Wolf, J. and Kofahl, B.
BMC Systems Biology 11
(1): 98.
13 October 2017
Insulin-like growth factor binding protein-2 (IGFBP2) is a key molecule in the MACC1-mediated platelet communication and metastasis of colorectal cancer cells.
Haschemi, R., Kobelt, D., Steinwarz, E., Schlesinger, M., Stein, U. and Bendas, G.
International Journal of Molecular Sciences 22
(22): 12195.
11 November 2021
Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-xL in a strictly caspase-3-dependent manner in human carcinoma cells.
Hasenjaeger, A., Gillissen, B., Mueller, A., Normand, G., Hemmati, P.G., Schuler, M., Doerken, B. and Daniel, P.T.
Oncogene 23
(26): 4523-4535.
3 June 2004
Common structural constituents confer IkappaB activity to NF-kappaB p105 and IkappaB/MAD-3.
Hatada, E.N., Naumann, M. and Scheidereit, C.
EMBO Journal 12
(7): 2781-2788.
July 1993
Gonadal sex and temperature independently influence germ cell differentiation and meiotic progression in Trachemys scripta.
Hatkevich, T., Tezak, B.M., Acemel, R.D., Yee Chung, V.W., Lupiáñez, D.G. and Capel, B.
Proceedings of the National Academy of Sciences of the United States of America 122
(1): e2413191121.
7 January 2025
Cellular senescence predicts treatment outcome in metastasised colorectal cancer.
Haugstetter, A.M., Loddenkemper, C., Lenze, D., Groene, J., Standfuss, C., Petersen, I., Doerken, B. and Schmitt, C.A.
British Journal of Cancer 103
(4): 505-509.
10 August 2010
Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V., Durrieu-Gaillard, S., Dumay-Odelot, H., Da Silva, D., Rey, C., Prochazkova, M., Roeder, R.G., Besser, D. and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107
(9): 4176-4181.
2 March 2010
Widely applicable, extended flow cytometric stem cell enumeration panel for quality control of advanced cellular products.
Haussmann, K., Streitz, M., Takvorian, A., Grund, J., Skenderi, Z., Tietze-Bürger, C., Movassaghi, K., Künkele, A., Blum, A. and Bullinger, L.
Scientific Reports 12
(1): 17995.
26 October 2022
An individual patient-data comparison of combined modality therapy and ABVD alone for patients with limited-stage Hodgkin lymphoma.
Hay, A.E., Klimm, B., Chen, B.E., Goergen, H., Shepherd, L.E., Fuchs, M., Gospodarowicz, M.K., Borchmann, P., Connors, J.M., Markova, J., Crump, M., Lohri, A., Winter, J.N., Doerken, B., Pearcey, R.G., Diehl, V., Horning, S.J., Eich, H.T., Engert, A. and Meyer, R.M.
Annals of Oncology 24
(12): 3065-3069.
December 2013
Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT.
Hayashida, N., Fujimoto, M., Tan, K., Prakasam, R., Shinkawa, T., Li, L., Ichikawa, H., Takii, R. and Nakai, A.
EMBO Journal 29
(20): 3459-3469.
20 October 2010
CD4+ T cell dependent B cell recovery and function after autologous hematopoietic stem cell transplantation.
Heck, C., Steiner, S., Kaebisch, E.M., Frentsch, M., Wittenbecher, F., Scheibenbogen, C., Hanitsch, L.G., Nogai, A., le Coutre, P., Bullinger, L., Blau, I.W. and Na, I.K.
Frontiers in Immunology 12
: 736137.
September 2021
Structure of a classical MHC class I molecule that binds "non-classical" ligands.
Hee, C.S., Gao, S., Loll, B., Miller, M.M., Uchanska-Ziegler, B., Daumke, O. and Ziegler, A.
PLoS Biology 8
(12): e1000557.
7 December 2010
Expression, purification and preliminary X-ray crystallographic analysis of the chicken MHC class I molecule YF1*7.1.
Hee, C.S., Gao, S., Miller, M.M., Goto, R.M., Ziegler, A., Daumke, O. and Uchanska-Ziegler, B.
Acta Crystallographica Section F 65
(Pt 4): 422-425.
1 April 2009
Alternate splicing of mouse fusin/CXC chemokine receptor-4: stromal cell-derived factor-1α is a ligand for both CXC chemokine receptor-4 isoforms.
Heesen, M., Berman, M.A., Höpken, U.E., Gerard, N.P. and Dorf, M.E.
Journal of Immunology 158
(8): 3561-3564.
15 April 1997
Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia.
Hegazy, A.N., Krönke, J., Angermair, S., Schwartz, S., Weidinger, C., Keller, U., Treskatsch, S., Siegmund, B. and Schneider, T.
BMC Infectious Diseases 22
(1): 537.
13 June 2022
Key factors regulating Plasmodium berghei sporozoite survival and transformation revealed by an automated visual assay.
Hegge, S., Kudryashev, M., Barniol, L. and Frischknecht, F.
FASEB Journal 24
(12): 5003-5012.
December 2010
Automated classification of Plasmodium sporozoite movement patterns reveals a shift towards productive motility during salivary gland infection.
Hegge, S., Kudryashev, M., Smith, A. and Frischknecht, F.
Biotechnology Journal 4
(6): 903-913.
June 2009
Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants.
Hehlmann, R., Lauseker, M., Saußele, S., Pfirrmann, M., Krause, S., Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Heim, D., Brümmendorf, T.H., Fabarius, A., Haferlach, C., Schlegelberger, B., Müller, M.C., Jeromin, S., Proetel, U., Kohlbrenner, K., Voskanyan, A., Rinaldetti, S., Seifarth, W., Spieß, B., Balleisen, L., Goebeler, M.C., Hänel, M., Ho, A., Dengler, J., Falge, C., Kanz, L., Kremers, S., Burchert, A., Kneba, M., Stegelmann, F., Köhne, C.A., Lindemann, H.W., Waller, C.F., Pfreundschuh, M., Spiekermann, K., Berdel, W.E., Müller, L., Edinger, M., Mayer, J., Beelen, D.W., Bentz, M., Link, H., Hertenstein, B., Fuchs, R., Wernli, M., Schlegel, F., Schlag, R., de Wit, M., Trümper, L., Hebart, H., Hahn, M., Thomalla, J., Scheid, C., Schafhausen, P., Verbeek, W., Eckart, M.J., Gassmann, W., Pezzutto, A., Schenk, M., Brossart, P., Geer, T., Bildat, S., Schäfer, E., Hochhaus, A. and Hasford, J.
Leukemia 31
(11): 2398-2406.
November 2017
High-risk additional chromosomal abnormalities at low blast counts herald death by CML.
Hehlmann, R., Voskanyan, A., Lauseker, M., Pfirrmann, M., Kalmanti, L., Rinaldetti, S., Kohlbrenner, K., Haferlach, C., Schlegelberger, B., Fabarius, A., Seifarth, W., Spieß, B., Wuchter, P., Krause, S., Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Burchert, A., Brümmendorf, T.H., Hasford, J., Hochhaus, A., Saußele, S. and Baccarani, M.
Leukemia 34
(8): 2074-2086.
August 2020
Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Heidenreich, S., Witte, N., Weber, P., Goehring, I., Tolkachov, A., von Loeffelholz, C., Döcke, S., Bauer, M., Stockmann, M., Pfeiffer, A.F.H., Birkenfeld, A.L., Pietzke, M., Kempa, S., Muenzner, M. and Schupp, M.
Nature Communications 8
(1): 384.
30 August 2017
The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Heider, M., Eichner, R., Stroh, J., Morath, V., Kuisl, A., Zecha, J., Lawatscheck, J., Baek, K., Garz, A.K., Rudelius, M., Deuschle, F.C., Keller, U., Lemeer, S., Verbeek, M., Götze, K.S., Skerra, A., Weber, W.A., Buchner, J., Schulman, B.A., Kuster, B., Fernández-Sáiz, V. and Bassermann, F.
Molecular Cell 81
(6): 1170-1186.
18 March 2021
Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
Heinig, K., Gätjen, M., Grau, M., Stache, V., Anagnostopoulos, I., Gerlach, K., Niesner, R.A., Cseresnyes, Z., Hauser, A.E., Lenz, P., Hehlgans, T., Brink, R., Westermann, J., Dörken, B., Lipp, M., Lenz, G., Rehm, A. and Höpken, U.E.
Cancer Discovery 4
: 1448-1465.
December 2014
Diagnostic work-up of rectal bleeding in general practice.
Heintze, C., Matysiak-Klose, D., Kroehn, T., Wolf, U., Brand, A., Meisner, C., Fischer, I., Wehrmeyer, H. and Braun, V.
British Journal of General Practice 55
(510): 14-19.
1 January 2005
The interaction domain of the redox protein adrenodoxin is mandatory for binding of the electron acceptor CYP11A1, but is not required for binding of the electron donor adrenodoxin reductase.
Heinz, A., Hannemann, F., Mueller, J.J., Heinemann, U. and Bernhardt, R.
Biochemical and Biophysical Research Communications 338
(9): 491-498.
29 August 2005
ssHMM: extracting intuitive sequence-structure motifs from high-throughput RNA-binding protein data.
Heller, D., Krestel, R., Ohler, U., Vingron, M. and Marsico, A.
Nucleic Acids Research 45
(19): 11004-11018.
2 November 2017
Environmental constraints guide migration of malaria parasites during transmission.
Hellmann, J.K., Münter, S., Kudryashev, M., Schulz, S., Heiss, K., Müller, A.K., Matuschewski, K., Spatz, J.P., Schwarz, U.S. and Frischknecht, F.
PLoS Pathogens 7
(6): e1002080.
16 June 2011
DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens.
Hellmeier, J., Platzer, R., Eklund, A.S., Schlichthaerle, T., Karner, A., Motsch, V., Schneider, M.C., Kurz, E., Bamieh, V., Brameshuber, M., Preiner, J., Jungmann, R., Stockinger, H., Schütz, G.J., Huppa, J.B. and Sevcsik, E.
Proceedings of the National Academy of Sciences of the United States of America 118
(4): e2016857118.
26 January 2021
A DNA origami-based biointerface to interrogate the spatial requirements for sensitized T-Cell antigen recognition.
Hellmeier, J., Platzer, R., Huppa, J.B. and Sevcsik, E.
Methods in Molecular Biology 2654
: 277-302.
28 April 2023
Strategies for the site-specific decoration of DNA origami nanostructures with functionally intact proteins.
Hellmeier, J., Platzer, R., Mühlgrabner, V., Schneider, M.C., Kurz, E., Schütz, G.J., Huppa, J.B. and Sevcsik, E.
ACS Nano 15
(9): 15057-15068.
28 September 2021
Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
Hellmuth, K., Grosskopf, S., Lum, C.T., Wuertele, M., Roeder, N., von Kries, J.P., Rosario, M., Rademann, J. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 105
(20): 7275-7280.
20 May 2008
A comparison of nine machine learning mutagenicity models and their application for predicting pyrrolizidine alkaloids.
Helma, C., Schöning, V., Drewe, J. and Boss, P.
Frontiers in Pharmacology 12
: 708050.
22 July 2021
Recurrent chromosomal aberrations in INK4a/ARF defective primary lymphomas predict drug responses in vivo.
Helmrich, A., Lee, S., O'Brien, P., Doerken, B., Lowe, S.W., Schroeck, E. and Schmitt, C.A.
Oncogene 24
: 4174-4182.
1 January 2005
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Helmsauer, K., Valieva, M.E., Ali, S., Chamorro Gonzalez, R., Schöpflin, R., Röefzaad, C., Bei, Y., Dorado Garcia, H., Rodriguez-Fos, E., Puiggròs, M., Kasack, K., Haase, K., Keskeny, C., Chen, C.Y., Kuschel, L.P., Euskirchen, P., Heinrich, V., Robson, M.I., Rosswog, C., Toedling, J., Szymansky, A., Hertwig, F., Fischer, M., Torrents, D., Eggert, A., Schulte, J.H., Mundlos, S., Henssen, A.G. and Koche, R.P.
Nature Communications 11
(1): 5823.
16 November 2020
Bak functionally complements for loss of Bax during p14(ARF)-induced mitochondrial apoptosis in human cancer cells.
Hemmati, P.G., Guener, D., Gillissen, B., Wendt, J., von Haefen, C., Chinnadurai, G., Doerken, B. and Daniel, P.T.
Oncogene 25
(50): 6582-6594.
26 October 2006
Systematic genetic dissection of p14(ARF)-mediated mitochondrial cell death signaling reveals a key role for p21(CDKN1) and the BH3-only protein Puma/bbc3.
Hemmati, P.G., Mueer, A., Gillissen, B., Overkamp, T., Milojkovic, A., Wendt, J., Doerken, B. and Daniel, P.T.
Journal of Molecular Medicine 88
(6): 609-622.
June 2010
Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.
Hemmati, P.G., Normand, G., Gillissen, B., Wendt, J., Doerken, B. and Daniel, P.T.
Oncogene 27
(53): 6707-6719.
4 December 2008
Loss of p21 disrupts p14ARF-induced G1 cell cycle arrest but augments p14ARF-induced apoptosis in human carcinoma cells.
Hemmati, P.G., Normand, G., Verdoodt, B., von Haefen, C., Hasenjaeger, A., Guener, D., Wendt, J., Doerken, B. and Daniel, P.T.
Oncogene 24
(25): 4114-4128.
1 January 2005
Cytogenetic risk grouping by the monosomal karyotype classification is superior in predicting the outcome of acute myeloid leukemia undergoing allogeneic stem cell transplantation in complete remission.
Hemmati, P.G., Schulze-Luckow, A., Terwey, T.H., le Coutre, P., Vuong, L.G., Doerken, B. and Arnold, R.
European Journal of Haematology 92
(2): 102-110.
February 2014
Reduced intensity conditioning prior to allogeneic stem cell transplantation in first complete remission is effective in patients with acute myeloid leukemia and an intermediate-risk karyotype.
Hemmati, P.G., Terwey, T.H., Massenkeil, G., le Coutre, P., Vuong, L.G., Neuburger, S., Doerken, B. and Arnold, R.
International Journal of Hematology 91
(3): 436-445.
April 2010
Allogeneic stem cell transplantation for refractory acute myeloid leukemia: a single center analysis of long-term outcome.
Hemmati, P.G., Terwey, T.H., Na, I.K., Jehn, C.F., le Coutre, P., Vuong, L.G., Doerken, B. and Arnold, R.
European Journal of Haematology 95
(6): 498-506.
December 2015
A modified EBMT risk score predicts the outcome of patients with acute myeloid leukemia receiving allogeneic stem cell transplants.
Hemmati, P.G., Terwey, T.H., le Coutre, P., Vuong, L.G., Massenkeil, G., Doerken, B. and Arnold, R.
European Journal of Haematology 86
(4): 305-316.
April 2011
Adenovirus-mediated overexpression of p14ARF induces p53 and Bax-independent apoptosis.
Hemmati, P.G., Gillissen, B., von Haefen, C., Wendt, J., Staerck, L., Guener, D., Doerken, B. and Daniel, P.T.
Oncogene 21
(20): 3149-3161.
9 May 2002
Impact of early remission by induction therapy on allogeneic stem cell transplantation for acute myeloid leukemia with an intermediate risk karyotype in first complete remission.
Hemmati, P.G., Terwey, T.H., Na, I.K., le Coutre, P., Jehn, C.F., Vuong, L.G., Dörken, B. and Arnold, R.
European Journal of Haematology 94
(5): 431-438.
May 2015
Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation.
Hemmati, P.G., Vuong, L.G., Terwey, T.H., Jehn, C.F., Le Coutre, P., Penack, O., Na, I.K., Dörken, B. and Arnold, R.
European Journal of Haematology 98
(2): 160-168.
February 2017
Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative.
Hendriks, H.R., Govaerts, A.S., Fichtner, I., Burtles, S., Westwell, A.D. and Peters, G.J.
British Journal of Cancer 117
(2): 195-202.
11 July 2017
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Henke, N., Schmidt-Ullrich, R., Dechend, R., Park, J.K., Qadri, F., Wellner, M., Obst, M., Gross, V., Dietz, R., Luft, F.C., Scheidereit, C. and Mueller, D.N.
Circulation Research 101
(3): 268-276.
3 August 2007
Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature.
Henne, W.M., Kent, H.M., Ford, M.G.J., Hegde, B.G., Daumke, O., Butler, P.J.G., Mittal, R., Langen, R., Evans, P.R. and McMahon, H.T.
Structure 15
(7): 839-52.
July 2007
HEK293-based production platform for γ-retroviral (SIN-) vectors: application for safe and efficient transfer of COL7A1 cDNA.
Hennig, K., Raasch, L., Kolbe, C., Weidner, S., Leisegang, M., Uckert, W., Titeux, M., Hovnanian, A., Kuehlcke, K. and Loew, R.
Human Gene Therapy Clinical Development 25
(4): 218-228.
December 2014
CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: Modulation by FTY720.
Henning, G., Ohl, H., Junt, T., Reiterer, P., Brinkmann, V., Nakano, H., Hohenberger, W., Lipp, M. and Foerster, R.
Journal of Experimental Medicine 194
(12): 1875-1881.
17 December 2001
CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programs in neuroblastoma cells.
Henrich, K.O., Bauer, T., Schulte, J., Ehemann, V., Deubzer, H., Gogolin, S., Muth, D., Fischer, M., Benner, A., König, R., Schwab, M. and Westermann, F.
Cancer Research 71
(8): 3142-3151.
15 April 2011
Transplantation of human acute myeloid leukemia (AML) cells in immunodeficient mice reveals altered cell surface phenotypes and expression of human endothelial markers.
Henschler, R., Goettig, S., Junghahn, I., Bug, G., Seifried, E., Mueller, A.M. and Fichtner, I.
Leukemia Research 29
(10): 1191-1199.
1 January 2005
Targeting MYCN-driven transcription by BET-bromodomain inhibition.
Henssen, A., Althoff, K., Odersky, A., Beckers, A., Koche, R., Speleman, F., Schäfers, S., Bell, E., Nortmeyer, M., Westermann, F., De Preter, K., Florin, A., Heukamp, L., Spruessel, A., Astrahanseff, K., Lindner, S., Sadowski, N., Schramm, A., Astorgues-Xerri, L., Riveiro, M.E., Eggert, A., Cvitkovic, E. and Schulte, J.H.
Clinical Cancer Research 22
(10): 2470-2481.
May 2016
BET bromodomain protein inhibition is a therapeutic option for medulloblastoma.
Henssen, A., Thor, T., Odersky, A., Heukamp, L., El-Hindy, N., Beckers, A., Speleman, F., Althoff, K., Schäfers, S., Schramm, A., Sure, U., Fleischhack, G., Eggert, A. and Schulte, J.H.
Oncotarget 4
(11): 2080-2095.
November 2013
Cytoarchitecture and probability maps of the human medial orbitofrontal cortex.
Henssen, A., Zilles, K., Palomero-Gallagher, N., Schleicher, A., Mohlberg, H., Gerboga, F., Eickhoff, S.B., Bludau, S. and Amunts, K.
Cortex 75
: 87-112.
February 2016
Genomic DNA transposition induced by human PGBD5.
Henssen, A.G., Henaff, E., Jiang, E., Eisenberg, A.R., Carson, J.R., Villasante, C.M., Ray, M., Still, E., Burns, M., Gandara, J., Feschotte, C., Mason, C.E. and Kentsis, A.
eLife 4
: e10565.
25 September 2015
Forward genetic screen of human transposase genomic rearrangements.
Henssen, A.G., Jiang, E., Zhuang, J., Pinello, L., Socci, N.D., Koche, R., Gonen, M., Villasante, C.M., Armstrong, S.A., Bauer, D.E., Weng, Z. and Kentsis, A.
BMC Genomics 17
: 548.
4 August 2016
PGBD5 promotes site-specific oncogenic mutations in human tumors.
Henssen, A.G., Koche, R., Zhuang, J., Jiang, E., Reed, C., Eisenberg, A., Still, E., MacArthur, I.C., Rodriguez-Fos, E., Gonzalez, S., Puiggròs, M., Blackford, A.N., Mason, C.E., de Stanchina, E., Gönen, M., Emde, A.K., Shah, M., Arora, K., Reeves, C., Socci, N.D., Perlman, E., Antonescu, C.R., Roberts, C.W.M., Steen, H., Mullen, E., Jackson, S.P., Torrents, D., Weng, Z., Armstrong, S.A. and Kentsis, A.
Nature Genetics 49
(7): 1005-1014.
July 2017
Targeting tachykinin receptors in neuroblastoma.
Henssen, A.G., Odersky, A., Szymansky, A., Seiler, M., Althoff, K., Beckers, A., Speleman, F., Schäfers, S., De Preter, K., Astrahanseff, K., Struck, J., Schramm, A., Eggert, A., Bergmann, A. and Schulte, J.H.
Oncotarget 8
(1): 430-443.
3 January 2017
Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.
Henssen, A.G., Reed, C., Jiang, E., Garcia, H.D., von Stebut, J., MacArthur, I.C., Hundsdoerfer, P., Kim, J.H., de Stanchina, E., Kuwahara, Y., Hosoi, H., Ganem, N.J., Dela Cruz, F., Kung, A.L., Schulte, J.H., Petrini, J.H. and Kentsis, A.
Science Translational Medicine 9
(414): eaam9078.
1 November 2017
A role for GPx3 in activity of normal and leukemia stem cells.
Herault, O., Hope, K.J., Deneault, E., Mayotte, N., Chagraoui, J., Wilhelm, B.T., Cellot, S., Sauvageau, M., Andrade-Navarro, M.A., Hebert, J. and Sauvageau, G.
Journal of Experimental Medicine 209
(5): 895-901.
7 May 2012
Relation between stressful life events, neuropeptides and cytokines: results from the LISA birth cohort study.
Herberth, G., Weber, A., Roeder, S., Elvers, H.D., Kraemer, U., Schins, R.P., Diez, U., Borte, M., Heinrich, J., Schaefer, T., Herbarth, O. and Lehmann, I.
Pediatric Allergy and Immunology 19
(8): 722-729.
December 2008
Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.
Herda, S., Heimann, A., Obermayer, B., Ciraolo, E., Althoff, S., Ruß, J., Grunert, C., Busse, A., Bullinger, L., Pezzutto, A., Blankenstein, T., Beule, D. and Na, I.K.
International Journal of Cancer 148
(12): 3097-3110.
15 June 2021
CXCR4-targeted PET imaging of central nervous system B-cell lymphoma.
Herhaus, P., Lipkova, J., Lammer, F., Yakushev, I., Vag, T., Slotta-Huspenina, J., Habringer, S., Lapa, C., Pukrop, T., Hellwig, D., Wiestler, B., Buck, A.K., Deckert, M., Wester, H.J., Bassermann, F., Schwaiger, M., Weber, W.A., Menze, B. and Keller, U.
Journal of Nuclear Medicine 61
(12): 1765-1771.
1 December 2020
Angiotensin-(1-7) stimulates hematopoietic progenitor cells in vitro and in vivo.
Heringer-Walther, S., Eckert, K., Schumacher, S.M., Uharek, L., Wulf-Goldenberg, A., Gembardt, F., Fichtner, I., Schultheiss, H.P., Rodgers, K. and Walther, T.
Haematologica 94
(6): 857-860.
June 2009
Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.
Herlan, M., Vogel, F., Boernhovd, C., Neupert, W. and Reichert, A.S.
Journal of Biological Chemistry 278
(30): 27781-27788.
1 January 2003
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca, P., Vonficht, D., Schnell, A., Uckelmann, H.J., Bollhagen, A., Mahmoud, M.A.A., Landua, S.L., van der Salm, E., Trautmann, C., Raffel, S., Grünschläger, F., Lutz, R., Ghosh, M., Renders, S., Correia, N., Donato, E., Dixon, K.O., Hirche, C., Andresen, C., Robens, Cl., Werner, P.S., Boch, T., Eisel, D., Osen, W., Pilz, F., Przybylla, A., Klein, C., Buchholz, F., Milsom, M.D., Essers, M.A.G., Eichmüller, S.B., Hofmann, W.K., Nowak, D., Hübschmann, D., Hundemer, M., Thiede, C., Bullinger, L., Müller-Tidow, C., Armstrong, S.A., Trumpp, A., Kuchroo, V.K. and Haas, S.
Cell Stem Cell 29
(5): 760-775.
5 May 2022
Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study.
Hernández-Sánchez, A., González, T., Sobas, M., Sträng, E., Castellani, G., Abáigar, M., Valk, P.J.M., Villaverde Ramiro, Á., Benner, A., Metzeler, K.H., Azibeiro, R., Tettero, J.M., Martínez-López, J., Pratcorona, M., Martínez Elicegui, J., Mills, K.I., Thiede, C., Sanz, G., Döhner, K., Heuser, M., Haferlach, T., Turki, A.T., Reinhardt, D., Schulze-Rath, R., Barbus, M., Hernández-Rivas, J.M., Huntly, B., Ossenkoppele, G., Döhner, H. and Bullinger, L.
Leukemia 38
(9): 1929-1937.
September 2024
Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
Herrlinger, U., Tzaridis, T., Mack, F., Steinbach, J.P., Schlegel, U., Sabel, M., Hau, P., Kortmann, R.D., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Bähr, O., Uhl, M., Seidel, C., Tabatabai, G., Kowalski, T., Ringel, F., Schmidt-Graf, F., Suchorska, B., Brehmer, S., Weyerbrock, A., Renovanz, M., Bullinger, L., Galldiks, N., Vajkoczy, P., Misch, M., Vatter, H., Stuplich, M., Schäfer, N., Kebir, S., Weller, J., Schaub, C., Stummer, W., Tonn, J.C., Simon, M., Keil, V.C., Nelles, M., Urbach, H., Coenen, M., Wick, W., Weller, M., Fimmers, R., Schmid, M., Hattingen, E., Pietsch, T., Coch, C. and Glas, M.
Lancet 393
(10172): 678-688.
16 February 2019
CTLA4 promotes Tyk2-STAT3 dependent B-cell oncogenecity.
Herrmann, A., Lahtz, C., Nagao, T., Song, J.Y., Chan, W.C., Lee, H., Yue, C., Look, T., Muelfarth, R., Li, W., Jenkins, K., Williams, J., Budde, L.E., Forman, S.J., Kwak, L.W., Blankenstein, T. and Yu, H.
Cancer Research 77
(18): 5118-5128.
15 September 2017
Transitory dasatinib-resistant states in KIT(mut) t(8;21) acute myeloid leukemia cells correlate with altered KIT expression.
Herrmann, M.D., Lennerz, J.K., Bullinger, L., Bartholomae, S., Holzmann, K., Westhoff, M.A., Corbacioglu, S. and Debatin, K.M.
Experimental Hematology 42
(2): 90-100.
February 2014
DNA damage signaling instructs polyploid macrophage fate in granulomas.
Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Münke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S., Sieweke, M.H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M.M., Voll, R.E., Deshmukh, S.D., Prinz, M., Goldmann, T., Hölscher, C., Hauser, A.E., Lopez-Contreras, A.J., Grün, D., Gorgoulis, V., Diefenbach, A., Henneke, P. and Triantafyllopoulou, A.
Cell 167
(5): 1264-1280.
17 November 2016
Detection of signature volatiles for cariogenic microorganisms.
Hertel, M., Preissner, R., Gillissen, B., Schmidt-Westhausen, A.M., Paris, S. and Preissner, S.
European Journal of Clinical Microbiology & Infectious Diseases 35
(2): 235-244.
February 2016
Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair.
Herzig, J.K., Bullinger, L., Tasdogan, A., Zimmermann, P., Schlegel, M., Teleanu, V., Weber, D., Rücker, F.G., Paschka, P., Dolnik, A., Schneider, E., Kuchenbauer, F., Heidel, F.H., Buske, C., Döhner, H., Döhner, K. and Gaidzik, V.I.
Oncotarget 8
(56): 95038-95053.
10 November 2017
A phase II trial to evaluate the combination of pixantrone and obinutuzumab for patients with relapsed aggressive lymphoma: Final results of the prospective, multicentre GOAL trial.
Hess, G., Hüttmann, A., Witzens-Harig, M., Dreyling, M.H., Keller, U., Marks, R., Ernst, T., Pott, C., Viardot, A., Frontzek, F., Trautmann, M., Ruckes, C., Deuster, O., Rosenwald, A., Theobald, M. and Lenz, G.
British Journal of Haematology 198
(3): 482-491.
1 April 2022
Final results of a phase I/II trial of the combination Bendamustine and Rituximab with Temsirolimus (BeRT) in relapsed mantle cell lymphoma and follicular lymphoma.
Hess, G., Wagner, K., Keller, U., La Rosee, P., Atta, J., Hübel, K., Lerchenmueller, C., Schoendube, D., Witzens-Harig, M., Ruckes, C., Medler, C., van Oordt, C., Klapper, W., Theobald, M. and Dreyling, M.
HemaSphere 4
(3): e398.
June 2020
Partitioned learning of deep Boltzmann machines for SNP data.
Hess, M., Lenz, S., Blätte, T.J., Bullinger, L. and Binder, H.
Bioinformatics 33
(20): 3173-3180.
October 2017
Vaccine-instructed intratumoral IFN-γ enables regression of autochthonous mouse prostate cancer in allogeneic T cell transplantation.
Hess Michelini, R., Manzo, T., Sturmheit, T., Basso, V., Rocchi, M., Freschi, M., Listopad, J.J., Blankenstein, T., Bellone, M. and Mondino, A.
Cancer Research 73
(15): 4641-4652.
1 August 2013
Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
Hessenberger, M., Zerbes, R.M., Rampelt, H., Kunz, S., Xavier, A.H., Purfürst, B., Lilie, H., Pfanner, N., van der Laan, M. and Daumke, O.
Nature Communications 8
: 15258.
31 May 2017
Interplay of cadherin-mediated cell adhesion and canonical wnt signaling.
Heuberger, J. and Birchmeier, W.
Cold Spring Harbor Perspectives in Biology 2
(2): a002915.
February 2010
Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J., Kosel, F., Qi, J., Grossmann, K.S., Rajewsky, K. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 111
(9): 3472-3477.
4 March 2014
High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J., Grinat, J., Kosel, F., Liu, L., Kunz, S., Vidal, R.O., Keil, M., Haybaeck, J., Robine, S., Louvard, D., Regenb