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Jump to: Abdelilah-Seyfried, Salim | Akalin, Altuna (BIMSB) | Alexander, Christiane | Andrade Navarro, Miguel | Bader, Michael | Bargou, Ralf C. | Behlke, Joachim | Bergmann, Martin W. | Besser, Daniel | Beule, Dieter (MDC/BIH) | Bielka, Heinz | Bimmler, Marion | Birchmeier, Walter | Birchmeier-Kohler, Carmen | Blankenstein, Thomas | Calkhoven, Cornelis F. | Cardoso, Cristina | Chekulaeva, Marina (BIMSB) | Chen, Wei (BIMSB/BIH) | Damaschun, Gregor | Daniel, Peter | Daumke, Oliver | De la Rosa, Kathrin | Deubzer, Hedwig (ECRC) | Di Virgilio, Michela | Diecke, Sebastian (MDC/BIH) | Dietz, Rainer | Dittmar, Gunnar | Doerken, Bernd (MDC/ECRC) | Falcke, Martin | Falk, Kirsten | Fichtner, Iduna | Fielitz, Jens (ECRC) | Fischer, Christian (ECRC) | Forslund, Sofia (MDC/ECRC) | Ganten, Detlev | Gargiulo, Gaetano | Garratt, Alistair N. | Geier, Christian (ECRC) | Gerhardt, Holger | Gerull, Brenda | Gollasch, Maik (ECRC) | Gossen, Manfred | Gotthardt, Michael | Hammes-Lewin, Annette | Heinemann, Udo | Henssen, Anton (ECRC) | Heuser, Arnd | Hirsch, Christian | Hoepken, Uta | Huebner, Norbert | Ivics, Zoltan | Izsvak, Zsuzsanna | Janz, Martin / Mathas, Stephan (MDC/ECRC) | Jentsch, Thomas | Jung, Christiane | Junker, Jan Philipp (BIMSB) | Karsten, Uwe | Kemmner, Wolfgang | Kempa, Stefan (BIMSB) | Kempermann, Gerd | Kettenmann, Helmut | Kettritz, Ralph (ECRC) | Klaassen, Sabine (ECRC) | Klussmann, Enno | Koehler, Matthias | Krappmann, Daniel | Kuehn, Ralf (MDC/BIH) | Lacadie, Scott | Landthaler, Markus (BIMSB) | Leutz, Achim | Lewin, Gary | Lipp, Martin | Loewer, Alexander (BIMSB) | Luft, Friedrich C. (MDC/ECRC) | Lupianez, Dario (BIMSB) | Matthes, Eckart | Mertins, Philipp (MDC/BIH) | Meyer, Irmtraud (BIMSB) | Morano, Ingo | Mueller, Dominik N. (MDC/ECRC) | Mueller, Dominik N. / Dechend, Ralph (ECRC) | Na, Il-Kang (ECRC) | Niendorf, Thoralf | Obermayer, Benedikt | Ohler, Uwe (BIMSB) | Panakova, Daniela | Paul, Friedemann (ECRC) | Peters, Oliver (ECRC) | Pezzutto, Antonio | PhD Programme | Pombo, Ana (BIMSB) | Poole, Kathryn | Poulet, James | Poy, Matthew | Preibisch, Stephan (BIMSB) | Preissner, Robert | Prigione, Alessandro | Purfuerst, Bettina | Raile, Klemens (ECRC) | Rajewsky, Klaus | Rajewsky, Nikolaus (BIMSB) | Rathjen, Fritz G. | Rehm, Armin | Reich, Jens | Reszka, Regina | Rocks, Oliver | Roepke, Torsten Kai (ECRC) | Roetzschke, Olaf | Rosenbauer, Frank | Ruckpaul, Klaus | Sauer, Sascha (BIMSB) | Saumweber, Harald | Scheidereit, Claus | Scherneck, Siegfried | Schmidt-Ott, Kai | Schmitt, Clemens | Schreiber, Adrian (ECRC) | Schuetz, Anja | Schulz-Menger, Jeanette (ECRC) | Schunck, Wolf-Hagen | Schwarz, Roland (BIMSB) | Selbach, Matthias | Sieweke, Michael | Siffrin, Volker (ECRC) | Sklenar, Heinz | Sommer, Thomas | Spagnoli, Francesca | Sperling, Silke (ECRC) | Sporbert, Anje | Spuler, Simone (ECRC) | Stade, Katrin | Stein, Ulrike (MDC/ECRC) | Tannert, Christof | Thierfelder, Ludwig | Tursun, Baris (BIMSB) | Uckert, Wolfgang | Von Kries, Jens Peter / Nazaré, Marc | Waiczies, Sonia (ECRC) | Walther, Wolfgang | Wang, Jichang | Wanker, Erich | Welfle, Heinz | Willnow, Thomas E. | Wittmann-Liebold, Brigitte | Woehler, Andrew (BIMSB) | Wolf, Jana | Wunderlich, Volker | Zenke, Martin | Ziebold, Ulrike | Zinzen, Robert (BIMSB)

Abdelilah-Seyfried, Salim

Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S. and Riemke, P. and Schoenheit, J. and Lenze, D. and Stumm, J. and Hoogenkamp, M. and Lagendijk, A. and Heinz, S. and Bonifer, C. and Bakkers, J. and Abdelilah-Seyfried, S. and Hummel, M. and Rosenbauer, F.
Blood 118 (8): 2275-2284. 25 August 2011

Akalin, Altuna (BIMSB)

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. and Rom, A. and Franke, V. and Imami, K. and Arrey, G. and Terne, M. and Woehler, A. and Akalin, A. and Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling.
Karabacak Calviello, A. and Hirsekorn, A. and Wurmus, R. and Yusuf, D. and Ohler, U.
Genome Biology 20 (1): 42. 21 February 2019

Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets via protocol-specific bias modeling.
Karabacak Calviello, A. and Hirsekorn, A. and Wurmus, R. and Yusuf, D. and Ohler, U.
bioRxiv : 284364. 19 March 2018

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. and Ofenbauer, A. and Bulut, S.I. and Uyar, B. and Baytek, G. and Sommermeier, A. and Seelk, S. and He, M. and Hirsekorn, A. and Vucicevic, D. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
Kolundzic, E. and Ofenbauer, A. and Uyar, B. and Sommermeier, A. and Seelk, S. and He, M. and Baytek, G. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
bioRxiv : 185116. 6 September 2017

Degrons in cancer.
Meszaros, B. and Kumar, M. and Gibson, T.J. and Uyar, B. and Dosztanyi, Z.
Science Signaling 10 (470): eaak9982. 14 March 2017

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. and Kirchner, M. and Uyar, B. and Cheng, J.Y. and Russo, G. and Hernandez-Miranda, L.R. and Szymborska, A. and Zauber, H. and Rudolph, I.M. and Willnow, T.E. and Akalin, A. and Haucke, V. and Gerhardt, H. and Birchmeier, C. and Kühn, R. and Krauss, M. and Diecke, S. and Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

Mutations in disordered regions cause disease by creating endocytosis motifs.
Meyer, K. and Uyar, B. and Kirchner, M. and Cheng, J. and Akalin, A. and Selbach, M.
bioRxiv : 141622. 24 May 2017

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N. and Kolesnichenko, M. and Beaudette, P. and Popp, O. and Uyar, B. and Sun, W. and Tufan, A.B. and Perder, B. and Akalin, A. and Chen, W. and Mertins, P. and Dittmar, G. and Hinz, M. and Scheidereit, C.
EMBO Journal 37 (24): e98658. 14 December 2018

The conserved histone chaperone LIN-53 links lifespan and healthspan regulation in C. elegans.
Muethel, S. and Uyar, B. and He, M. and Krause, A. and Vitrinel, B. and Bulut, S. and Vasiljevic, D. and Akalin, A. and Kempa, S. and Tursun, B.
bioRxiv : 539015. 2 February 2019

Deciphering human ribonucleoprotein regulatory networks.
Mukherjee, N. and Wessels, H.H. and Lebedeva, S. and Sajek, M. and Ghanbari, M. and Garzia, A. and Munteanu, A. and Yusuf, D. and Farazi, T. and Hoell, J.I. and Akat, K.M. and Akalin, A. and Tuschl, T. and Ohler, U.
Nucleic Acids Research 47 (2): 570-581. 25 January 2019

RCAS: an RNA centric annotation system for transcriptome-wide regions of interest.
Uyar, B. and Yusuf, D. and Wurmus, R. and Rajewsky, N. and Ohler, U. and Akalin, A.
Nucleic Acids Research 45 (10): e91. 2 June 2017

Global identification of functional microRNA-mRNA interactions in Drosophila.
Wessels, H.H. and Lebedeva, S. and Hirsekorn, A. and Wurmus, R. and Akalin, A. and Mukherjee, N. and Ohler, U.
Nature Communications 10 : 1626. 9 April 2019

Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.
Wyler, E. and Menegatti, J. and Franke, V. and Kocks, C. and Boltengagen, A. and Hennig, T. and Theil, K. and Rutkowski, A. and Ferrai, C. and Baer, L. and Kermas, L. and Friedel, C. and Rajewsky, N. and Akalin, A. and Dölken, L. and Grässer, F. and Landthaler, M.
Genome Biology 18 (1): 209. 31 October 2017

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L. and Kärgel, E. and Franke, V. and McShane, E. and Schulz-Beiss, K.W. and Patone, G. and Schleussner, N. and Kolesnichenko, M. and Hübner, N. and Daumke, O. and Selbach, M. and Akalin, A. and Mathas, S. and Scheidereit, C.
Blood 133 (13): 1489-1494. 28 March 2019

Alexander, Christiane

Characterization of protein-binding to the spinach chloroplast psbA mRNA 5' untranslated region.
Alexander, C. and Faber, N. and Klaff, P.
Nucleic Acids Research 26 (10): 2265-2272. 15 May 1998

Andrade Navarro, Miguel

Mining the literature: new methods to exploit keyword profiles.
Andrade-Navarro, M.A.
Genome Medicine 4 (10): 81. 30 October 2012

A method for cell type marker discovery by high-throughput gene expression analysis of mixed cell populations.
Andrade-Navarro, M.A. and Kanji, F. and Palii, C.G. and Brand, M. and Atkins, H. and Perez-Iratxeta, C.
BMC Biotechnology 13 (1): 80. 3 October 2013

Peer2ref: a peer-reviewer finding web tool that uses author disambiguation.
Andrade-Navarro, M.A. and Palidwor, G.A. and Perez-Iratxeta, C.
BioData Mining 5 (1): 14. 7 September 2012

PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries.
Barbosa-Silva, A. and Fontaine, J.F. and Donnard, E.R. and Stussi, F. and Ortega, J.M. and Andrade-Navarro, M.A.
BMC Bioinformatics 12 (1): 435. 9 November 2011

PRC1-mediated gene silencing in pluripotent ES cells: function and evolution.
Becker, M. and Mah, N. and Zdzieblo, D. and Li, X. and Mer, A.S. and Andrade-Navarro, M.A. and Mueller, A.M.
Epigenetics and Human Health 2015 : 141-166. 18 November 2014

CAFE: an R package for the detection of gross chromosomal abnormalities from gene expression microarray data.
Bollen, S. and Leddin, M. and Andrade-Navarro, M.A. and Mah, N.
Bioinformatics 30 (10): 1484-1485. 15 May 2014

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, A.M. and Vockentanz, L. and Kharazi, S. and Huska, M.R. and Mancini, E. and Scheller, M. and Kuhl, C. and Enns, A. and Prinz, M. and Jaenisch, R. and Nerlov, C. and Leutz, A. and Andrade-Navarro, M.A. and Jacobsen, S.E. and Rosenbauer, F.
Nature Genetics 41 (11): 1207-1215. November 2009

Arabidopsis KCBP interacts with AIR9 but stays in the cortical division zone throughout mitosis via its MyTH4-FERM domain.
Buschmann, H. and Dols, J. and Kopischke, S. and Pena, E.J. and Andrade-Navarro, M.A. and Heinlein, M. and Szymanski, D.B. and Zachgo, S. and Doonan, J.H. and Lloyd, C.W.
Journal of Cell Science 28 (11): 2033-2046. 1 June 2015

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N. and Naumann, H. and Ruzittu, S. and Mah, N. and Pongrac, I.M. and Cozzitorto, C. and Hommel, A. and Andrade-Navarro, M.A. and Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8 : 14127. 13 February 2017

Identification of 2-[4-[(4-methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers.
Cheng, X. and Dimou, E. and Alborzinia, H. and Wenke, F. and Goehring, A. and Reuter, S. and Mah, N. and Fuchs, H. and Andrade-Navarro, M.A. and Adjaye, J. and Gul, S. and Harms, C. and Utikal, J. and Klipp, E. and Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58 (12): 4976-4983. 25 June 2015

Ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4.
Cheng, X. and Yoshida, H. and Raoofi, D. and Saleh, S. and Alborzinia, H. and Wenke, F. and Goehring, A. and Reuter, S. and Mah, N. and Fuchs, H.R. and Andrade-Navarro, M.A. and Adjaye, J. and Gul, S. and Utikal, J. and Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58 (1): 5742-5750. 13 August 2015

Preimplantation development regulatory pathway construction through a text-mining approach.
Donnard, E. and Barbosa-Silva, A. and Guedes, R.L. and Fernandes, G.R. and Velloso, H. and Kohn, M.J. and Andrade-Navarro, M.A. and Ortega, J.M.
BMC Genomics 12 (Suppl 4): S3. 22 December 2011

Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma.
Fehlker, M. and Huska, M.R. and Joens, T. and Andrade-Navarro, M.A. and Kemmner, W.
BMC Cancer 14 (1): 64. 5 February 2014

Assessment of curated phenotype mining in neuropsychiatric disorder literature.
Fontaine, J.F. and Priller, J. and Spruth, E. and Perez-Iratxeta, C. and Andrade-Navarro, M.A.
Methods 74 : 90-96. March 2015

PDBpaint, a visualization webservice to tag protein structures with sequence annotations.
Fournier, D. and Andrade-Navarro, M.A.
Bioinformatics 27 (18): 2605-2606. 15 September 2011

Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D. and Luft, F.C. and Bader, M. and Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90 (5): 495-508. May 2012

Functional and genomic analyses of α-solenoid proteins.
Fournier, D. and Palidwor, G.A. and Shcherbinin, S. and Szengel, A. and Schaefer, M.H. and Perez-Iratxeta, C. and Andrade-Navarro, M.A.
PLoS ONE 8 (11): e79894. 21 November 2013

mBISON: Finding miRNA target over-representation in gene lists from ChIP-sequencing data.
Gebhardt, M.L. and Mer, A.S. and Andrade-Navarro, M.A.
BMC Research Notes 8 (1): 157. 16 April 2015

Similarity in targets with REST points to neural and glioblastoma related miRNAs.
Gebhardt, M.L. and Reuter, S. and Mrowka, R. and Andrade-Navarro, M.A.
Nucleic Acids Research 42 (9): 5436-5446. 14 May 2014

Alkemio: association of chemicals with biomedical topics by text and data mining.
Gijon-Correas, J.A. and Andrade-Navarro, M.A. and Fontaine, J.F.
Nucleic Acids Research 42 (W1): W422-W429. 1 July 2014

Bio++: efficient extensible libraries and tools for computational molecular evolution.
Gueguen, L. and Gaillard, S. and Boussau, B. and Gouy, M. and Groussin, M. and Rochette, N.C. and Bigot, T. and Fournier, D. and Pouyet, F. and Cahais, V. and Bernard, A. and Scornavacca, C. and Nabholz, B. and Haudry, A. and Dachary, L. and Galtier, N. and Belkhir, K. and Dutheil, J.Y.
Molecular Biology and Evolution 30 (8): 1745-1750. August 2013

Alterations of pre-mRNA splicing in human inflammatory bowel disease.
Haesler, R. and Kerick, M. and Mah, N. and Hultschig, C. and Richter, G. and Bretz, F. and Sina, C. and Lehrach, H. and Nietfeld, W. and Schreiber, S. and Rosenstiel, P.
European Journal of Cell Biology 90 (6-7): 603-611. June 2011

A role for GPx3 in activity of normal and leukemia stem cells.
Herault, O. and Hope, K.J. and Deneault, E. and Mayotte, N. and Chagraoui, J. and Wilhelm, B.T. and Cellot, S. and Sauvageau, M. and Andrade-Navarro, M.A. and Hebert, J. and Sauvageau, G.
Journal of Experimental Medicine 209 (5): 895-901. 7 May 2012

DNA microarray and miRNA analyses reinforce the classification of follicular thyroid tumors.
Jacques, C. and Guillotin, D. and Fontaine, J.F. and Franc, B. and Mirebeau-Prunier, D. and Fleury, A. and Malthiery, Y. and Savagner, F.
Journal of Clinical Endocrinology and Metabolism 98 (5): E981-E989. May 2013

Computational approaches to discovering noncoding RNA.
Krzyzanowski, P.M. and Muro, E.M. and Andrade-Navarro, M.A.
Wiley Interdisciplinary Reviews: RNA 3 (4): 567-579. July 2012

A customized class of functions for modeling and clustering gene expression profiles in embryonic stem cells.
Li, S. and Andrade-Navarro, M. and Sankoff, D.
Lecture Notes in Computer Science 5167 : 92-103. 2008

Tissue specific subnetworks and characteristics of publicly available human protein interaction databases.
Lopes, T.J. and Schaefer, M. and Shoemaker, J. and Matsuoka, Y. and Fontaine, J.F. and Neumann, G. and Andrade-Navarro, M.A. and Kawaoka, Y. and Kitano, H.
Bioinformatics 27 (17): 2414-2421. 1 September 2011

Prediction of protein secondary structure from circular dichroism using theoretically derived spectra.
Louis-Jeune, C. and Andrade-Navarro, M.A. and Perez-Iratxeta, C.
Proteins: Structure, Function, and Bioinformatics 80 (2): 374-381. February 2012

In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans.
Ma, L. and Tan, Z. and Teng, Y. and Hoersch, S. and Horvitz, H.R.
RNA 17 (12): 2201-2211. December 2011

A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in caenorhabditis elegans.
Mansisidor, A.R. and Cecere, G. and Hoersch, S. and Jensen, M.B. and Kawli, T. and Kennedy, L.M. and Chavez, V. and Tan, M.W. and Lieb, J.D. and Grishok, A.
PLoS Genetics 7 (9): e1002299. September 2011

Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.
McNeill, B. and Perez-Iratxeta, C. and Mazerolle, C. and Furimsky, M. and Mishina, Y. and Andrade-Navarro, M.A. and Wallace, V.A.
Molecular and Cellular Neuroscience 49 (3): 333-340. March 2012

A novel approach for protein subcellular location prediction using amino acid exposure.
Mer, A.S. and Andrade-Navarro, M.A.
BMC Bioinformatics 14 (1): 342. 28 November 2013

Estrogen-related receptor alpha modulates lactate dehydrogenase activity in thyroid tumors.
Mirebeau-Prunier, D. and Le Pennec, S. and Jacques, C. and Fontaine, J.F. and Gueguen, N. and Boutet-Bouzamondo, N. and Donnart, A. and Malthiery, Y. and Savagner, F.
PLoS ONE 8 (3): e58683. 13 March 2013

Natural antisense transcripts within pseudogenes: an EST survey.
Muro, E.M. and Andrade-Navarro, M.A.
In: Non-coding RNAs and epigenetic regulation of gene expression : drivers of natural selection. Caister Academic Press (U.K.), Norfolk, 99-108. ISBN 978-1-904455-94-3 February 2012

Functional evidence of post-transcriptional regulation by pseudogenes.
Muro, E.M. and Mah, N. and Andrade-Navarro, M.A.
Biochimie 93 (11): 1916-1921. November 2011

The pseudogenes of Mycobacterium leprae reveal the functional relevance of gene order within operons.
Muro, E.M. and Mah, N. and Moreno-Hagelsieb, G. and Andrade-Navarro, M.A.
Nucleic Acids Research 39 (5): 1732-1738. 1 March 2011

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Naba, A. and Clauser, K.R. and Hoersch, S. and Liu, H. and Carr, S.A. and Hynes, R.O.
Molecular & Cellular Proteomics 11 (4): M111.014647. 1 April 2012

Preliminary evaluation of the CellFinder literature curation pipeline for gene expression in kidney cells and anatomical parts.
Neves, M. and Damaschun, A. and Mah, N. and Lekschas, F. and Seltmann, S. and Stachelscheid, H. and Fontaine, J.F. and Kurtz, A. and Leser, U.
Database 2013 (2013): bat020. 18 April 2013

ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics.
Norton, M. and Ng, A.C. and Baird, S. and Dumoulin, A. and Shutt, T. and Mah, N. and Andrade-Navarro, M.A. and McBride, H.M. and Screaton, R.A.
Science Signaling 7 (310): ra10. 28 January 2014

Using cited references to improve the retrieval of related biomedical documents.
Ortuno, F.M. and Rojas, I. and Andrade-Navarro, M.A. and Fontaine, J.F.
BMC Bioinformatics 14 : 113. 27 March 2013

A reference guide for tree analysis and visualization.
Pavlopoulos, G.A. and Soldatos, T.G. and Barbosa-Silva, A. and Schneider, R.
BioData Mining 3 : 1. 22 February 2010

Towards completion of the Earth's proteome.
Perez-Iratxeta, C. and Palidwor, G. and Andrade-Navarro, M.A.
EMBO Reports 8 (12): 1135-1141. 1 December 2007

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
Petrakis, S. and Rasko, T. and Russ, J. and Friedrich, R.P. and Stroedicke, M. and Riechers, S.P. and Muehlenberg, K. and Moeller, A. and Reinhardt, A. and Vinayagam, A. and Schaefer, M.H. and Boutros, M. and Tricoire, H. and Andrade-Navarro, M.A. and Wanker, E.E.
PLoS Genetics 8 (8): e1002897. 16 August 2012

Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
Petrakis, S. and Schaefer, M.H. and Wanker, E.E. and Andrade-Navarro, M.A.
BioEssays 35 (6): 503-507. June 2013

Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.
Riemke, P. and Czeh, M. and Fischer, J. and Walter, C. and Ghani, S. and Zepper, M. and Agelopoulos, K. and Lettermann, S. and Gebhardt, M.L. and Mah, N. and Weilemann, A. and Grau, M. and Groening, V. and Haferlach, T. and Lenze, D. and Delwel, R. and Prinz, M. and Andrade-Navarro, M.A. and Lenz, G. and Dugas, M. and Mueller-Tidow, C. and Rosenbauer, F.
EMBO Journal 35 (22): 2399-2416. 15 November 2016

CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A. and Qadri, F. and Leukel, L. and Yilmaz, R. and Fontaine, J.F. and Sihn, G. and Bader, M. and Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123 (3): 1343-1347. 1 March 2013

The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily.
Sanchez-Pulido, L. and Andrade-Navarro, M.A.
BMC Biochemistry 8 : 23. 8 November 2007

Paired sage-microarray expression data sets reveal antisense transcripts differentially expressed in embryonic stem cell differentiation.
Sandie, R. and Porter, C.J. and Palidwor, G.A. and Price, F. and Krzyzanowski, P.M. and Muro, E.M. and Hoersch, S. and Smith, M. and Campbell, P.A. and Perez-Iratxeta, C. and Rudnicki, M.A. and Andrade-Navarro, M.A.
In: Computational Biology of Embryonic Stem Cells. Bentham Science (U.S.A.), Oak Park, 193-215. ISBN 978-1-608-05025-3 2012

HIPPIE: integrating protein interaction networks with experiment based quality scores.
Schaefer, M.H. and Fontaine, J.F. and Vinayagam, A. and Porras, P. and Wanker, E.E. and Andrade-Navarro, M.A.
PLoS ONE 7 (2): e31826. 14 February 2012

Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.
Schaefer, M.H. and Lopes, T.J.S. and Mah, N. and Shoemaker, J.E. and Matsuoka, Y. and Fontaine, J.F. and Louis-Jeune, C. and Eisfeld, A.J. and Neumann, G. and Perez-Iratxeta, C. and Kawaoka, Y. and Kitano, H. and Andrade-Navarro, M.A.
PLoS Computational Biology 9 (1): e1002860. 3 January 2013

Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Schaefer, M.H. and Wanker, E.E. and Andrade-Navarro, M.A.
Nucleic Acids Research 40 (10): 4273-4287. 1 May 2012

SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.
Schmid, F. and Wang, Q. and Huska, M.R. and Andrade-Navarro, M.A. and Lemm, M. and Fichtner, I. and Dahlmann, M. and Kobelt, D. and Walther, W. and Smith, J. and Schlag, P.M. and Stein, U.
Oncogene 35 (46): 5942-5952. 17 November 2016

PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.
Schönheit, J. and Kuhl, C. and Gebhardt, M.L. and Klett, F.F. and Riemke, P. and Scheller, M. and Huang, G. and Naumann, R. and Leutz, A. and Stocking, C. and Priller, J. and Andrade-Navarro, M.A. and Rosenbauer, F.
Cell Reports 3 (5): 1617-1628. 30 May 2013

CELDA - an ontology for the comprehensive representation of cells in complex systems.
Seltmann, S. and Stachelscheid, H. and Damaschun, A. and Jansen, L. and Lekschas, F. and Fontaine, J.F. and Nguyen-Dobinsky, T.N. and Leser, U. and Kurtz, A.
BMC Bioinformatics 14 : 228. 17 July 2013

Comparison of inter- and intraspecies variation in humans and fruit flies.
Shih, J. and Hodge, R. and Andrade-Navarro, M.A.
Genomics Data 3 : 49-54. March 2015

Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a piwi protein.
Simon, B. and Kirkpatrick, J.P. and Eckhardt, S. and Reuter, M. and Rocha, E.A. and Andrade-Navarro, M.A. and Sehr, P. and Pillai, R.S. and Carlomagno, T.
Structure 19 (2): 172-180. 9 February 2011

Caipirini: using gene sets to rank literature.
Soldatos, T.G. and O'Donoghue, S.I. and Satagopam, V.P. and Barbosa-Silva, A. and Pavlopoulos, G.A. and Wanderley-Nogueira, A.C. and Soares-Cavalcanti, N.M. and Schneider, R.
BioData Mining 5 (1): 1. 1 February 2012

CellFinder: a cell data repository.
Stachelscheid, H. and Seltmann, S. and Lekschas, F. and Fontaine, J.F. and Mah, N. and Neves, M. and Andrade-Navarro, M.A. and Leser, U. and Kurtz, A.
Nucleic Acids Research 42 (1): D950-D958. 1 January 2014

Armadillo motifs involved in vesicular transport.
Striegl, H. and Andrade-Navarro, M.A. and Heinemann, U.
PLoS ONE 5 (2): e8991. 1 February 2010

Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke, M. and Bounab, Y. and Strempel, N. and Klockmeier, K. and Yigit, S. and Friedrich, R.P. and Chaurasia, G. and Li, S. and Hesse, F. and Riechers, S.P. and Russ, J. and Nicoletti, C. and Boeddrich, A. and Wiglenda, T. and Haenig, C. and Schnoegl, S. and Fournier, D. and Graham, R.K. and Hayden, M.R. and Sigrist, S. and Bates, G.P. and Priller, J. and Andrade-Navarro, M.A. and Futschik, M.E. and Wanker, E.E.
Genome Research 25 (5): 701-713. May 2015

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
Suratanee, A. and Schaefer, M.H. and Betts, M.J. and Soons, Z. and Mannsperger, H. and Harder, N. and Oswald, M. and Gipp, M. and Ramminger, E. and Marcus, G. and Männer, R. and Rohr, K. and Wanker, E. and Russell, R.B. and Andrade-Navarro, M.A. and Eils, R. and König, R.
PLoS Computational Biology 10 (9): e1003814. 25 September 2014

Development and application of a DNA microarray-based yeast two-hybrid system.
Suter, B. and Fontaine, J.F. and Yildirimman, R. and Raskó, T. and Schaefer, M.H. and Rasche, A. and Porras, P. and Vázquez-Álvarez, B.M. and Russ, J. and Rau, K. and Foulle, R. and Zenkner, M. and Saar, K. and Herwig, R. and Andrade-Navarro, M.A. and Wanker, E.E.
Nucleic Acids Research 41 (3): 1496-507. 1 February 2013

Short tandem repeats in the inhibitory domain of the mineralocorticoid receptor: prediction of a β-solenoid structure.
Vlassi, M. and Brauns, K. and Andrade-Navarro, M.A.
BMC Structural Biology 13 (1): 17. 2 October 2013

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K. and Ullrich, F. and Muench, J. and Lazarow, K. and Lutter, D. and Mah, N. and Andrade-Navarro, M.A. and von Kries, J.P. and Stauber, T. and Jentsch, T.J.
Science 344 (6184): 634-638. 9 May 2014

In silico screening for pathogenesis related-2 gene candidates in Vigna uguiculata transcriptome.
Wanderley-Nogueira, A.C. and Da Mota Soares-Cavalcanti, N. and Belarmino, L.C. and Barbosa-Silva, A. and Kido, E.A. and Do Monte, S.J.H. and Pandolfi, V. and Calsa-Junior, T. and Benko-Iseppon, A.M.
Lecture Notes in Computer Science 6160 : 70-81. 2010

uORFdb - a comprehensive literature database on eukaryotic uORF biology.
Wethmar, K. and Barbosa-Silva, A. and Andrade-Navarro, M.A. and Leutz, A.
Nucleic Acids Research 42 (1): D60-D67. 1 January 2014

Comprehensive translational control of tyrosine kinase expression by upstream open reading frames.
Wethmar, K. and Schulz, J. and Muro, E.M. and Talyan, S. and Andrade-Navarro, M.A. and Leutz, A.
Oncogene 35 (13): 1736-1742. 31 March 2016

Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery.
Zhang, G. and Hoersch, S. and Amsterdam, A. and Whittaker, C.A. and Beert, E. and Catchen, J.M. and Farrington, S. and Postlethwait, J.H. and Legius, E. and Hopkins, N. and Lees, J.A.
PLoS Genetics 9 (8): e1003734. August 2013

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.
Zhang, G. and Hoersch, S. and Amsterdam, A. and Whittaker, C.A. and Lees, J.A. and Hopkins, N.
Proceedings of the National Academy of Sciences of the United States of America 107 (39): 16940-16945. 28 September 2010

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P. and Kaergel, E. and Heinig, M. and Fontaine, J.F. and Patone, G. and Muro, E.M. and Mathas, S. and Hummel, M. and Andrade-Navarro, M.A. and Hübner, N. and Scheidereit, C.
Genome Medicine 8 (1): 28. 17 March 2016

SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations.
von Eichborn, J. and Dunkel, M. and Gohlke, B.O. and Preissner, S.C. and Hoffmann, M.F. and Bauer, J.M.J. and Armstrong, J.D. and Schaefer, M.H. and Andrade-Navarro, M.A. and Le Novere, N. and Croning, M.D.R. and Grant, S.G.N. and van Nierop, P. and Smit, A.B. and Preissner, R.
Nucleic Acids Research 41 (D1): D834-D840. 1 January 2013

Bader, Michael

Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D. and Luft, F.C. and Bader, M. and Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90 (5): 495-508. May 2012

Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G. and Uhlemann, R. and Richter, N. and Klempin, F. and Wegner, S. and Staerck, L. and Wolf, S. and Uckert, W. and Kettenmann, H. and Endres, M. and Gertz, K.
Acta Neuropathologica 135 (4): 551. April 2018

CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A. and Qadri, F. and Leukel, L. and Yilmaz, R. and Fontaine, J.F. and Sihn, G. and Bader, M. and Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123 (3): 1343-1347. 1 March 2013

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.
Werth, M. and Walentin, K. and Aue, A. and Schoenheit, J. and Wuebken, A. and Pode-Shakked, N. and Vilianovitch, L. and Erdmann, B. and Dekel, B. and Bader, M. and Barasch, J. and Rosenbauer, F. and Luft, F.C. and Schmidt-Ott, K.M.
Development 137 (22): 3835-3845. November 2010

Bargou, Ralf C.

CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations.
Arce, S. and Luger, E. and Muehlinghaus, G. and Cassese, G. and Hauser, A. and Horst, A. and Lehnert, K. and Odendahl, M. and Hoenemann, D. and Heller, K.D. and Kleinschmidt, H. and Berek, C. and Doerner, T. and Krenn, V. and Hiepe, F. and Bargou, R. and Radbruch, A. and Manz, R.A.
Journal of Leukocyte Biology 75 : 1022-1028. 1 January 2004

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M. and Stuehmer, T. and Herrmann, P. and Bommert, K. and Doerken, B. and Bargou, R.C.
Blood 104 (12): 3712-3721. 1 January 2004

T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3-bispecific single-chain antibody construct1.
Dreier, T. and Baeuerle, P.A. and Fichtner, I. and Gruen, M. and Schlereth, B. and Lorenczewski, G. and Kufer, P. and Lutterbuese, R. and Riethmueller, G. and Gjorstrup, P. and Bargou, R.C.
Journal of Immunology 170 (8): 4397-4402. 15 April 2003

T-cell-mediated lysis of B cells induced by a CD19xCD3 bispecific single-chain antibody is perforin dependent and death receptor independent.
Gruen, M. and Bommert, K. and Bargou, R.C.
Cancer Immunology Immunotherapy 53 (7): 625-632. 1 January 2004

A novel recombinant bispecific single-chain antibody, bscWue-1 x CD3, induces T-cell-mediated cytotoxicity towards human multiple myeloma cells.
Hoenemann, D. and Kufer, P. and Rimpler, M.M. and Chatterjee, M. and Friedl, S. and Riecher, F. and Bommert, K. and Doerken, B. and Bargou, R.C.
Leukemia 18 (3): 636-644. 1 January 2004

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F. and Schulze-Proebsting, K. and Anagnostopoulos, I. and Muehlinghaus, G. and Chatterjee, M. and Mathas, S. and Bargou, R.C. and Manz, R. and Stein, H. and Doerken, B.
Blood 103 (9): 3511-3515. 1 January 2004

PI3-K/AKT/FKHR and MAPK signaling cascades are redundantly stimulated by a variety of cytokines and contribute independently to proliferation and survival of multiple myeloma cells.
Lentzsch, S. and Chatterjee, M. and Gries, M. and Bommert, K. and Gollasch, H. and Doerken, B. and Bargou, R.C.
Leukemia 18 (11): 1883-1890. 1 January 2004

Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S. and Gries, M. and Janz, M. and Bargou, R. and Doerken, B. and Mapara, M.Y.
Blood 101 (9): 3568-3573. 1 May 2003

Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19/anti-CD3 single-chain antibody construct.
Loeffler, A. and Gruen, M. and Wuchter, C. and Schriever, F. and Kufer, P. and Dreier, T. and Hanakam, F. and Baeuerle, P.A. and Bommert, K. and Karawajew, L. and Doerken, B. and Bargou, R.C.
Leukemia 17 (5): 900-909. May 2003

Behlke, Joachim

Oligomeric structure of mammalian purine nucleoside phosphorylase in solution determined by analytical ultracentrifugation.
Behlke, J. and Koellner, G. and Bzowska, A.
Zeitschrift fuer Naturforschung C, A Journal of Biosciences 60 (11-12): 927-931. November 2005

Protein crystallization with and without precipitants.
Behlke, J. and Marg, A. and Paeschke, M.
Journal of Applied Crystallography 30 (5/1): 559-560. 1 October 1997

Enhanced resolution of sedimentation coefficient distribution profiles by extrapolation to infinite time.
Behlke, J. and Ristau, O.
European Biophysics Journal 39 (3): 449-455. February 2010

Molecular mass determination by sedimentation velocity experiments and direct fitting of the concentration profiles.
Behlke, J. and Ristau, O.
Biophysical Journal 72 (1): 428-434. January 1997

Self-association of adrenodoxin studied by using analytical ultracentrifugation.
Behlke, J. and Ristau, O. and Mueller, E.C. and Hannemann, F. and Bernhardt, R.
Biophysical Chemistry 125 (1): 159-165. January 2007

In vitro and in vivo stability of the epsilon2zeta2 protein complex of the broad host-range Streptococcus pyogenes pSM19035 addiction system.
Camacho, A.G. and Misselwitz, R. and Behlke, J. and Ayora, S. and Welfle, K. and Meinhart, A. and Lara, B. and Saenger, W. and Welfle, H. and Alonso, J.C.
Biological Chemistry 383 (11): 1701-1713. November 2002

X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
Manjasetty, B.A. and Niesen, F.H. and Scheich, C. and Roske, Y. and Goetz, F. and Behlke, J. and Sievert, V. and Heinemann, U. and Buessow, K.
BMC Structural Biology 5 (14): 21. 14 December 2005

Crystal structures of human saposins C and D: implications for lipid recognition and membrane interactions.
Rossmann, M. and Schultz-Heienbrok, R. and Behlke, J. and Remmel, N. and Alings, C. and Sandhoff, K. and Saenger, W. and Maier, T.
Structure 16 (5): 809-817. 7 May 2008

Structural and functional characterization of human Iba proteins.
Schulze, J.O. and Quedenau, C. and Roske, Y. and Adam, T. and Schueler, H. and Behlke, J. and Turnbull, A.P. and Sievert, V. and Scheich, C. and Mueller, U. and Heinemann, U. and Buessow, K.
FEBS Journal 275 (18): 4627-4640. September 2008

CopR binds and bends its target DNA: a footprinting and fluorescence resonance energy transfer study.
Steinmetzer, K. and Behlke, J. and Brantl, S. and Lorenz, M.
Nucleic Acids Research 30 (9): 2052-2060. 1 May 2002

Beitraege zur Struktur und Funktion des kleinen Saeuger-Stressproteins HSP25 unter besonderer Beruecksichtigung der Wechselwirkung mit Actin.
Wieske, M.
UNSPECIFIED thesis, UNSPECIFIED. 22 September 1998

Bergmann, Martin W.

Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A. and Zelarayan, L. and Betney, R. and Gehrke, C. and Dunger, S. and Noack, C. and Busjahn, A. and Huelsken, J. and Taketo, M.M. and Birchmeier, W. and Dietz, R. and Bergmann, M.W.
Circulation Research 100 (9): 1353-1362. 11 May 2007

Besser, Daniel

Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
Besser, D. and Bardelli, A. and Didichenko, S. and Thelen, M. and Comoglio, P.M. and Ponzetto, C. and Nagamine, Y.
Oncogene 14 (6): 705-711. 13 February 1997

A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.
Besser, D. and Bromberg, J.F. and Darnell, J.E. and Hanafusa, H.
Molecular and Cellular Biology 19 (2): 1401-1409. February 1999

DNA methylation inhibits transcription by RNA polymerase III of a tRNA gene, but not of a 5S rRNA gene.
Besser, D. and Goetz, F. and Schulze-Forster, K. and Wagner, H. and Kroeger, H. and Simon, D.
FEBS Letters 269 (2): 358-362. 3 September 1990

Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts.
Besser, D. and Presta, M. and Nagamine, Y.
Cell Growth & Differentiation 6 (8): 1009-1017. August 1995

Urokinase-type plasminogen activator gene regulation by polyomavirus middle-T antigen.
Besser, D. and Urich, M. and Sakaue, M. and Messerschmitt, A. and Ballmer-Hofer, K. and Nagamine, Y.
Oncogene 11 (11): 2383-2391. 7 December 1995

Signal transduction and the u-PA/u-PAR system.
Besser, D. and Verde, P. and Nagamine, Y. and Blasi, F.
Fibrinolysis 10 (4): 215-237. July 1996

Stem cell biology-from basic research to regenerative medicine.
Besser, D.
Journal of Molecular Medicine 90 (7): 731-733. July 2012

Expression of nodal, lefty-A, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.
Besser, D.
Journal of Biological Chemistry 279 (43): 45076-45084. 1 January 2004

Replicative aging and differentiation potential of human adipose tissue-derived mesenchymal stromal cells expanded in pooled human or fetal bovine serum.
Bieback, K. and Hecker, A. and Schlechter, T. and Hofmann, I. and Brousos, N. and Redmer, T. and Besser, D. and Klueter, H. and Mueller, A.M. and Becker, M.
Cytotherapy 14 (5): 570-583. May 2012

Mesenchymal stromal cells (MSCs): science and f(r)iction.
Bieback, K. and Wuchter, P. and Besser, D. and Franke, W. and Becker, M. and Ott, M. and Pacher, M. and Ma, N. and Stamm, C. and Klueter, H. and Mueller, A. and Ho, A.D.
Journal of Molecular Medicine 90 (7): 773-782. July 2012

SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction.
Birge, R.B. and Knudsen, B.S. and Besser, D. and Hanafusa, H.
Genes to Cells 1 (7): 595-613. July 1996

Stat3 activation is required for cellular transformation by v-src.
Bromberg, J.F. and Horvath, C.M. and Besser, D. and Lathem, W.W. and Darnell, J.E.
Molecular and Cellular Biology 18 (5): 2553-2558. May 1998

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R. and Sternjak, A. and Wend, P. and Momma, S. and Campos, B. and Herrmann, I.M. and Graf, D. and Mitsiadis, T. and Herold-Mende, C. and Besser, D. and Synowitz, M. and Kettenmann, H. and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2.
D'Orazio, D. and Besser, D. and Marksitzer, R. and Kunz, C. and Hume, D.A. and Kiefer, B. and Nagamine, Y.
Gene 201 (1-2): 179-187. 12 November 1997

FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells.
Diecke, S. and Quiroga-Negreira, A. and Redmer, T. and Besser, D.
Cells Tissues Organs 188 (1-2): 52-61. July 2008

12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells.
El-Shemerly, M.Y. and Besser, D. and Nagasawa, M. and Nagamine, Y.
Journal of Biological Chemistry 272 (49): 30599-30602. 5 December 1997

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J. and Morkel, M. and Besser, D. and Budczies, J. and Kosel, F. and Brembeck, F.H. and Stein, U. and Fichtner, I. and Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V. and Durrieu-Gaillard, S. and Dumay-Odelot, H. and Da Silva, D. and Rey, C. and Prochazkova, M. and Roeder, R.G. and Besser, D. and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107 (9): 4176-4181. 2 March 2010

Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway.
Irigoyen, J.P. and Besser, D. and Nagamine, Y.
Journal of Biological Chemistry 272 (3): 1904-1909. 17 January 1997

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells.
James, D. and Levine, A.J. and Besser, D. and Hemmati-Brivanlou, A.
Development 132 (6): 1273-1282. March 2005

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.
Kaufman, W.L. and Kocman, I. and Agrawal, V. and Rahn, H.P. and Besser, D. and Gossen, M.
Nucleic Acids Research 36 (17): e111. October 2008

Transcriptional regulation of the murine urokinase-type plasminogen activator gene in skeletal myoblasts.
Miralles, F. and Ibanez-Tallon, I. and Parra, M. and Crippa, M. and Blasi, F. and Besser, D. and Nagamine, Y. and Munoz-Canoves, P.
Thrombosis and Haemostasis 81 (5): 767-774. May 1999

E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
Redmer, T. and Diecke, S. and Grigoryan, T. and Quiroga-Negreira, A. and Birchmeier, W. and Besser, D.
EMBO Reports 12 (7): 720-726. 1 July 2011

Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M. and Besser, D. and Benitah, S.A.
EMBO Reports 13 (1): 9-11. January 2012

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Su, F. and Overholtzer, M. and Besser, D. and Levine, A.J.
Genes & Development 16 (1): 46-57. 2002

Activation and nuclear translocation of mitogen-activated protein kinases by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase.
Urich, M. and el Shemerly, M.Y. and Besser, D. and Nagamine, Y. and Ballmer-Hofer, K.
Journal of Biological Chemistry 270 (49): 29286-29292. 8 December 1995

Protein kinase B beta/Akt2 plays a specific role in muscle differentiation.
Vandromme, M. and Rochat, A. and Meier, R. and Carnac, G. and Besser, D. and Hemmings, B.A. and Fernandez, A. and Lamb, N.J.
Journal of Biological Chemistry 276 (11): 8173-8179. 16 March 2001

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. and Xie, G. and Singh, M. and Ghanbarian, A.T. and Raskó, T. and Szvetnik, A. and Cai, H. and Besser, D. and Prigione, A. and Fuchs, N.V. and Schumann, G.G. and Chen, W. and Lorincz, M.C. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.
Wolfrum, C. and Besser, D. and Luca, E. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (20): 11624-11629. 30 September 2003

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src.
Wong, B.R. and Besser, D. and Kim, N. and Arron, J.R. and Vologodskaia, M. and Hanafusa, H. and Choi, Y.
Molecular Cell 4 (6): 1041-1049. December 1999

Independent and cooperative activation of chromosomal c-fos promoter by STAT3.
Yang, E. and Lerner, L. and Besser, D. and Darnell, J.E.
Journal of Biological Chemistry 278 (18): 15794-15799. 2 May 2003

Beule, Dieter (MDC/BIH)

The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A. and Babila, J.T. and Wiglenda, T. and Diez, L. and Jacob, M. and Nietfeld, W. and Huska, M.R. and Haenig, C. and Groenke, N. and Buntru, A. and Blanc, E. and Meier, J.C. and Vannoni, E. and Erck, C. and Friedrich, B. and Martens, H. and Neuendorf, N. and Schnoegl, S. and Wolfer, D.P. and Loos, M. and Beule, D. and Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26 (1): 109-120. 17 January 2019

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. and Friese, C. and Arina, A. and Idel, C. and Briesemeister, D. and Rothe, M. and Ivanov, A. and Szymborska, A. and Patone, G. and Kunz, S. and Sommermeyer, D. and Engels, B. and Leisegang, M. and Textor, A. and Fehling, H.J. and Fruttiger, M. and Lohoff, M. and Herrmann, A. and Yu, H. and Weichselbaum, R. and Uckert, W. and Hübner, N. and Gerhardt, H. and Beule, D. and Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

Bielka, Heinz

Arnold Graffi (1910-2006) : A pioneer of experimental cancer research.
Wunderlich, V. and Bielka, H.
Journal of Cancer Research and Clinical Oncology 132 (8): 483-485. August 2006

Bimmler, Marion

Antibodies to the alpha(1)-adrenergic receptor cause vascular impairments in rat brain as demonstrated by magnetic resonance angiography.
Karczewski, P. and Pohlmann, A. and Wagenhaus, B. and Wisbrun, N. and Hempel, P. and Lemke, B. and Kunze, R. and Niendorf, T. and Bimmler, M.
PLoS ONE 7 (7): e41602. 30 July 2012

Birchmeier, Walter

Gab1 and Mapk signaling are essential in the hair cycle and hair follicle stem cell quiescence.
Akilli Öztürk, Ö. and Pakula, H. and Chmielowiec, J. and Qi, J. and Stein, S. and Lan, L. and Sasaki, Y. and Rajewsky, K. and Birchmeier, W.
Cell Reports 13 (3): 561-572. 20 October 2015

Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.
Augustin, I. and Gross, J. and Baumann, D. and Korn, C. and Kerr, G. and Grigoryan, T. and Mauch, C. and Birchmeier, W. and Boutros, M.
Journal of Experimental Medicine 210 (9): 1761-1777. 26 August 2013

Role of β-catenin in synaptic vesicle localization and presynaptic assembly.
Bamji, S.X. and Shimazu, K. and Kimes, N. and Huelsken, J. and Birchmeier, W. and Lu, B. and Reichardt, L.F.
Neuron 40 (4): 719-731. November 2003

Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A. and Zelarayan, L. and Betney, R. and Gehrke, C. and Dunger, S. and Noack, C. and Busjahn, A. and Huelsken, J. and Taketo, M.M. and Birchmeier, W. and Dietz, R. and Bergmann, M.W.
Circulation Research 100 (9): 1353-1362. 11 May 2007

Control of beta-catenin signaling in tumor development.
Behrens, J.
Annals of the New York Academy of Sciences 910 : 21-35. June 2000

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Behrens, J. and Jerchow, B.A. and Wuertele, M. and Grimm, J. and Asbrand, C. and Wirtz, R. and Kuehl, M. and Wedlich, D. and Birchmeier, W.
Science 280 (5363): 596-599. 24 April 1998

Functional interaction of beta-catenin with the transcription factor LEF-1.
Behrens, J. and von Kries, J.P. and Kuehl, M. and Bruhn, L. and Wedlich, D. and Grosschedl, R. and Birchmeier, W.
Nature 382 (6592): 638-642. 15 August 1996

Expression of nodal, lefty-A, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.
Besser, D.
Journal of Biological Chemistry 279 (43): 45076-45084. 1 January 2004

Hormonal induction of functional differentiation and mammary-derived growth inhibitor expression in cultured mouse mammary gland explants.
Binas, B. and Spitzer, E. and Zschiesche, W. and Erdmann, B. and Kurtz, A. and Mueller, T. and Niemann, C. and Blenau, W. and Grosse, R.
In Vitro Cellular & Developmental Biology 28A (9-10): 625-634. September 1992

Molecular aspects of mesenchymal-epithelial interactions.
Birchmeier, C. and Birchmeier, W.
Annual Review of Cell Biology 9 : 511-540. 1993

Met, metastasis, motility and more.
Birchmeier, C. and Birchmeier, W. and Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003

Orchestrating Wnt signalling for metabolic liver zonation.
Birchmeier, W.
Nature Cell Biology 18 (5): 463-465. May 2016

Stem cells: Orphan receptors find a home.
Birchmeier, W.
Nature 476 (7360): 287-288. 18 August 2011

Cell adhesion and signal transduction in cancer.
Birchmeier, W.
EMBO Reports 6 (5): 413-417. 1 January 2005

Mittel zur Beeinflussung der Zelldifferenzierung und seine Verwendung.
Birchmeier, W.
DE19509792A1. 19 September 1996

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness.
Birchmeier, W. and Behrens, J.
Biochimica et Biophysica Acta 1198 (1): 11-26. 27 May 1994

The role of Irf6 in tooth epithelial invagination.
Blackburn, J. and Ohazama, A. and Kawasaki, K. and Otsuka-Tanaka, Y. and Liu, B. and Honda, K. and Rountree, R.B. and Hu, Y. and Kawasaki, M. and Birchmeier, W. and Schmidt-Ullrich, R. and Kinoshita, A. and Schutte, B.C. and Hammond, N.L. and Dixon, M.J. and Sharpe, P.T.
Developmental Biology 365 (1): 61-70. 1 May 2012

Balancing cell adhesion and Wnt signaling, the key role of beta-catenin.
Brembeck, F.H. and Rosario, M. and Birchmeier, W.
Current Opinion in Genetics & Development 16 (1): 51-59. February 2006

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Brembeck, F.H. and Schwarz-Romond, T. and Bakkers, J. and Wilhelm, S. and Hammerschmidt, M. and Birchmeier, W.
Genes & Development 18 (18): 2225-2230. 15 September 2004

BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H. and Wiese, M. and Zatula, N. and Grigoryan, T. and Dai, Y. and Fritzmann, J. and Birchmeier, W.
Gastroenterology 141 (4): 1359-1370. October 2011

Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.
Brinkmann, V. and Foroutan, H. and Sachs, M. and Weidner, K.M. and Birchmeier, W.
Journal of Cell Biology 131 (6 Pt. 1): 1573-1586. December 1995

Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas.
Busch, J. and Ralla, B. and Jung, M. and Wotschofsky, Z. and Trujillo-Arribas, E. and Schwabe, P. and Kilic, E. and Fendler, A. and Jung, K.
Journal of Experimental & Clinical Cancer Research 34 (1): 61. 14 June 2015

Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.
Cerrone, M. and Noorman, M. and Lin, X. and Chkourko, H. and Liang, F.X. and van der Nagel, R. and Hund, T. and Birchmeier, W. and Mohler, P. and van Veen, T.A. and van Rijen, H.V. and Delmar, M.
Cardiovascular Research 95 (4): 460-468. 1 September 2012

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R. and Sternjak, A. and Wend, P. and Momma, S. and Campos, B. and Herrmann, I.M. and Graf, D. and Mitsiadis, T. and Herold-Mende, C. and Besser, D. and Synowitz, M. and Kettenmann, H. and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

c-Met is essential for wound healing in the skin.
Chmielowiec, J. and Borowiak, M. and Morkel, M. and Stradal, T. and Munz, B. and Werner, S. and Wehland, J. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response.
Churin, Y. and Al Ghoul, L. and Kepp, O. and Meyer, T.E. and Birchmeier, W. and Naumann, M.
Journal of Cell Biology 161 (2): 249-255. 28 April 2003

The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3β interaction protein (GSKIP) regulates β-catenin through its interactions with both protein kinase A (PKA) and GSK3β.
Dema, A. and Schröter, M.F. and Perets, E. and Skroblin, P. and Moutty, M.C. and Deàk, V.A. and Birchmeier, W. and Klussmann, E.
Journal of Biological Chemistry 291 (37): 19618-19630. 9 September 2016

FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells.
Diecke, S. and Quiroga-Negreira, A. and Redmer, T. and Besser, D.
Cells Tissues Organs 188 (1-2): 52-61. July 2008

From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic acid and db-cAMP in vitro differentiation model.
Drab, M. and Haller, H. and Bychkov, R. and Erdmann, B. and Lindschau, C. and Haase, H. and Morano, I. and Luft, F.C. and Wobus, A.M.
FASEB Journal 11 (11): 905-915. September 1997

A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis.
Fang, L. and Zhu, Q. and Neuenschwander, M. and Specker, E. and Wulf-Goldenberg, A. and Weis, W.I. and von Kries, J.P. and Birchmeier, W.
Cancer Research 76 (4): 891-901. 15 February 2016

Beta-catenin regulates P-cadherin expression in mammary basal epithelial cells.
Faraldo, M.M. and Teuliere, J. and Deugnier, M.A. and Birchmeier, W. and Huelsken, J. and Thiery, J.P. and Cano, A. and Glukhova, M.A.
FEBS Letters 581 (5): 831-836. 6 March 2007

The translational potential of microRNAs as biofluid markers of urological tumours.
Fendler, A. and Stephan, C. and Yousef, G.M. and Kristiansen, G. and Jung, K.
Nature Reviews Urology 13 (12): 734-752. December 2016

Keratinocyte-specific ablation of protease-activated receptor-2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease.
Francis, N. and Ayodele, B.A. and O'Brien-Simpson, N.M. and Birchmeier, W. and Pike, R.N. and Pagel, C.N. and Mackie, E.J.
Cellular Microbiology 20 (11): e12891. November 2018

Circular RNAs: a new class of biomarkers as a rising interest in laboratory medicine.
Franz, A. and Rabien, A. and Stephan, C. and Ralla, B. and Fuchs, S. and Jung, K. and Fendler, A.
Clinical Chemistry and Laboratory Medicine 56 (12): 1992-2003. December 2018

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J. and Morkel, M. and Besser, D. and Budczies, J. and Kosel, F. and Brembeck, F.H. and Stein, U. and Fichtner, I. and Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B. and Heuser, A. and Wichter, T. and Paul, M. and Basson, C.T. and McDermott, D.A. and Lerman, B.B. and Markowitz, S.M. and Ellinor, P.T. and MacRae, C.A. and Peters, S. and Grossmann, K.S. and Drenckhahn, J. and Michely, B. and Sasse-Klaassen, S. and Birchmeier, W. and Dietz, R. and Breithardt, G. and Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36 (11): 1162-1164. November 2004

Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: Implications for cell adhesion and signaling.
Ghadimi, B.M. and Behrens, J. and Hoffmann, I. and Haensch, W. and Birchmeier, W. and Schlag, P.M.
European Journal of Cancer 35 (1): 60-65. January 1999

Targeting MET in cancer: rationale and progress.
Gherardi, E. and Birchmeier, W. and Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

Molecular signaling mechanisms of axon-glia communication in the peripheral nervous system.
Grigoryan, T. and Birchmeier, W.
BioEssays 37 (5): 502-513. May 2015

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T. and Stein, S. and Qi, J. and Wende, H. and Garratt, A.N. and Nave, K.A. and Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
Grigoryan, T. and Wend, P. and Klaus, A. and Birchmeier, W.
Genes & Development 22 (17): 2308-2341. 1 September 2008

Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
Grimm, J. and Sachs, M. and Britsch, S. and Di Cesare, S. and Schwarz-Romond, T. and Birchmeier, W.
Journal of Cell Biology 154 (2): 345-354. 23 July 2001

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S. and Eckert, C. and Arkona, C. and Radetzki, S. and Böhm, K. and Heinemann, U. and Wolber, G. and von Kries, J.P. and Birchmeier, W. and Rademann, J.
ChemMedChem 10 (5): 815-826. May 2015

Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
Grossmann, K.S. and Grund, C. and Huelsken, J. and Behrend, M. and Erdmann, B. and Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 167 (1): 149-160. 11 October 2004

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S. and Rosario, M. and Birchmeier, C. and Birchmeier, W.
Advances in Cancer Research 106 : 53-89. 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis.
Guenthert, U. and Schwaerzler, C. and Wittig, B. and Laman, J. and Ruiz, P. and Stauder, R. and Bloem, A. and Smadja-Joffe, F. and Zoeller, M. and Rolink, A.
Advances in Experimental Medicine and Biology 451 : 43-49. 1998

Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Hadjihannas, M.V. and Brueckner, M. and Jerchow, B. and Birchmeier, W. and Dietmaier, W. and Behrens, J.
Proceedings of the National Academy of Sciences of the United States of America 103 (28): 10747-10752. 11 July 2006

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V. and Durrieu-Gaillard, S. and Dumay-Odelot, H. and Da Silva, D. and Rey, C. and Prochazkova, M. and Roeder, R.G. and Besser, D. and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107 (9): 4176-4181. 2 March 2010

Shp-2 inhibitors, pharmaceutical compositions comprising them and their use for treating phosphatase-mediated diseases [Shp-2-Inhibitoren, Arzneimittel, die sie enthalten sowie deren Verwendung zur Behandlung von Phosphatasen-vermittelten Krankheiten].
Hellmuth, K. and Birchmeier, W.
EP1728790 ; WO06128909. 6 December 2006

Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
Hellmuth, K. and Grosskopf, S. and Lum, C.T. and Wuertele, M. and Roeder, N. and von Kries, J.P. and Rosario, M. and Rademann, J. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 105 (20): 7275-7280. 20 May 2008

Interplay of cadherin-mediated cell adhesion and canonical wnt signaling.
Heuberger, J. and Birchmeier, W.
Cold Spring Harbor Perspectives in Biology 2 (2): a002915. February 2010

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J. and Kosel, F. and Qi, J. and Grossmann, K.S. and Rajewsky, K. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 111 (9): 3472-3477. 4 March 2014

A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis.
Heuberger, J. and Hill, U. and Förster, S. and Zimmermann, K. and Malchin, V. and Kühl, A.A. and Stein, U. and Vieth, M. and Birchmeier, W. and Leutz, A.
Life Science Alliance 2 (1): e201800173. February 2019

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.
Hill, T.P. and Spaeter, D. and Taketo, M.M. and Birchmeier, W. and Hartmann, C.
Developmental Cell 8 (5): 727-738. 1 May 2005

Multiple roles of mesenchymal beta-catenin during murine limb patterning.
Hill, T.P. and Taketo, M.M. and Birchmeier, W. and Hartmann, C.
Development 133 (7): 1219-1229. 1 April 2006

Expression of multidrug resistance proteins (Mrps) in astrocytes of the mouse brain: a single cell rt-PCR study.
Hirrlinger, J. and Moeller, H. and Kirchhoff, F. and Dringen, R.
Neurochemical Research 30 (10): 1237-1244. 1 October 2005

Rap1 regulates the formation of E-cadherin-based cell-cell contacts.
Hogan, C. and Serpente, N. and Cogram, P. and Hosking, C.R. and Bialucha, C.U. and Feller, S.M. and Braga, V.M.M. and Birchmeier, W. and Fujita, Y.
Molecular and Cellular Biology 24 (15): 6690-6700. 1 January 2004

Wnt signaling in stem and cancer stem cells.
Holland, J.D. and Klaus, A. and Garratt, A.N. and Birchmeier, W.
Current Opinion in Cell Biology 25 (2): 254-264. April 2013

Combined Wnt/β-catenin, met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome.
Holland, J.D. and Györffy, B. and Vogel, R. and Eckert, K. and Valenti, G. and Fang, L. and Lohneis, P. and Elezkurtaj, S. and Ziebold, U. and Birchmeier, W.
Cell Reports 5 (5): 1214-1227. 12 December 2013

The transcriptional repressor Glis2 is a novel binding partner for p120 catenin.
Hosking, C.R. and Ulloa, F. and Hogan, C. and Ferber, E. and Figueroa, A. and Gevaert, K. and Birchmeier, W. and Briscoe, J. and Fujita, Y.
Molecular Biology of the Cell 18 (5): 1918-1927. 1 May 2007

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
Huelsken, J. and Birchmeier, W. and Behrens, J.
Journal of Cell Biology 127 (6 Pt. 2): 2061-2069. December 1994

Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J. and Vogel, R. and Brinkmann, V. and Erdmann, B. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 148 (3): 567-578. 7 February 2000

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
Huelsken, J. and Vogel, R. and Erdmann, B. and Cotsarelis, G. and Birchmeier, W.
Cell 105 (4): 533-545. 18 May 2001

Plakoglobin is essential for myocardial compliance but dispensable for myofibril insertion into adherens junctions.
Isac, C.M. and Ruiz, P. and Pfitzmaier, B. and Haase, H. and Birchmeier, W. and Morano, I.
Journal of Cellular Biochemistry 72 (1): 8-15. 1 January 1999

Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling.
Jaervinen, E. and Salazar-Ciudad, I. and Birchmeier, W. and Taketo, M.M. and Jernvall, J. and Thesleff, I.
Proceedings of the National Academy of Sciences of the United States of America 103 (49): 18627-18632. 5 December 2006

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Jeannet, G. and Scheller, M. and Scarpellino, L. and Duboux, S. and Gardiol, N. and Back, J. and Kuttler, F. and Malanchi, I. and Birchmeier, W. and Leutz, A. and Huelsken, J. and Held, W.
Blood 111 (1): 142-149. 1 January 2008

Genetische Analyse von Conductin durch zielgerichtete Mutagenese in der Maus.
Jerchow, B.
UNSPECIFIED thesis, UNSPECIFIED. 6 May 2003

Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Juerchott, K. and Kuban, R.J. and Krech, T. and Bluethgen, N. and Stein, U. and Walther, W. and Friese, C. and Kielbasa, S.M. and Ungethuem, U. and Lund, P. and Knoesel, T. and Kemmner, W. and Morkel, M. and Fritzmann, J. and Schlag, P.M. and Birchmeier, W. and Krueger, T. and Sperling, S. and Sers, C. and Royer, H.D. and Herzel, H. and Schaefer, R.
PLoS Genetics 6 (12): e1001231. 2 December 2010

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.
Kaufman, W.L. and Kocman, I. and Agrawal, V. and Rahn, H.P. and Besser, D. and Gossen, M.
Nucleic Acids Research 36 (17): e111. October 2008

Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
Keilhack, H. and Mueller, M. and Boehmer, S.A. and Frank, C. and Weidner, K.M. and Birchmeier, W. and Ligensa, T. and Berndt, A. and Kosmehl, H. and Gunther, B. and Mueller, T. and Birchmeier, C. and Boehmer, F.D.
Journal of Cell Biology 152 (2): 325-334. 22 January 2001

Developmental signaling in myocardial progenitor cells: A comprehensive view of Bmp- and Wnt/beta-catenin signaling.
Klaus, A. and Birchmeier, W.
Pediatric Cardiology 30 (5): 609-616. July 2009

Wnt signalling and its impact on development and cancer.
Klaus, A. and Birchmeier, W.
Nature Reviews Cancer 8 (5): 387-398. May 2008

Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Klaus, A. and Mueller, M. and Schulz, H. and Saga, Y. and Martin, J.F. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 109 (27): 10921-10926. 3 July 2012

Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.
Klaus, A. and Saga, Y. and Taketo, M.M. and Tzahor, E. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104 (47): 18531-18536. 20 November 2007

Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas.
Koch, A. and Hrychyk, A. and Hartmann, W. and Waha, A. and Mikeska, T. and Waha, A. and Schueller, U. and Soerensen, N. and Berthold, F. and Goodyer, C.G. and Wiestler, O.D. and Birchmeier, W. and Behrens, J. and Pietsch, T.
International Journal of Cancer 121 (2): 284-291. 15 July 2007

Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas.
Koch, A. and Weber, N. and Waha, A. and Hartmann, W. and Denkhaus, D. and Behrens, J. and Birchmeier, W. and von Schweinitz, D. and Pietsch, T.
Journal of Pathology 204 (5): 546-554. 1 January 2004

Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells.
Kuerbitz, C. and Heise, D. and Redmer, T. and Goumas, F. and Arlt, A. and Lemke, J. and Rimbach, G. and Kalthoff, H. and Trauzold, A.
Cancer Science 102 (4): 728-734. April 2011

The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway.
Lamothe, B. and Yamada, M. and Schaeper, U. and Birchmeier, W. and Lax, I. and Schlessinger, J.
Molecular and Cellular Biology 24 (13): 5657-5666. 1 January 2004

Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.
Lan, L. and Holland, J.D. and Qi, J. and Grosskopf, S. and Rademann, J. and Vogel, R. and Gyoerffy, B. and Wulf-Goldenberg, A. and Birchmeier, W.
EMBO Journal 34 (11): 1493-1508. 3 June 2015

MicroRNA signature helps distinguish early from late biochemical failure in prostate cancer.
Lichner, Z. and Fendler, A. and Saleh, C. and Nasser, A.N. and Boles, D. and Al-Haddad, S. and Kupchak, P. and Dharsee, M. and Nuin, P.S. and Evans, K.R. and Jung, K. and Stephan, C. and Fleshner, N.E. and Yousef, G.M.
Clinical Chemistry 59 (11): 1595-1603. November 2013

Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients.
Lu, H. and Busch, J. and Jung, M. and Rabenhorst, S. and Ralla, B. and Kilic, E. and Mergemeier, S. and Budach, N. and Fendler, A. and Jung, K.
Clinica Chimica Acta 452 : 109-119. 15 January 2016

Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism.
MacRae, C.A. and Birchmeier, W. and Thierfelder, L.
Journal of Clinical Investigation 116 (7): 1825-1828. July 2006

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
Malanchi, I. and Peinado, H. and Kassen, D. and Hussenet, T. and Metzger, D. and Chambon, P. and Huber, M. and Hohl, D. and Cano, A. and Birchmeier, W. and Huelsken, J.
Nature 452 (7187): 650-653. 3 April 2008

Diversin regulates heart formation and gastrulation movements in development.
Moeller, H. and Jenny, A. and Schaeffer, H.J. and Schwarz-Romond, T. and Mlodzik, M. and Hammerschmidt, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 103 (43): 15900-15905. 24 October 2006

Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway.
Momeny, M. and Ghasemi, R. and Valenti, G. and Miranda, M. and Zekri, A. and Zarrinrad, G. and Javadikooshesh, S. and Yaghmaie, M. and Alimoghaddam, K. and Ghavamzadeh, A. and Ghaffari, S.H.
Tumor Biology 37 (3): 3913-3923. March 2016

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Momeny, M. and Saunus, J.M. and Marturana, F. and McCart Reed, A.E. and Black, D. and Sala, G. and Iacobelli, S. and Holland, J.D. and Yu, D. and Da Silva, L. and Simpson, P.T. and Khanna, K.K. and Chenevix-Trench, G. and Lakhani, S.R.
Oncotarget 6 (6): 3932-3946. 19 February 2015

β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.
Morkel, M. and Huelsken, J. and Wakamiya, M. and Ding, J. and van de Wetering, M. and Clevers, H. and Taketo, M.M. and Behringer, R.R. and Shen, M.M. and Birchmeier, W.
Development 130 (25): 6283-6294. 1 January 2003

β-catenin is required for specification of proximal/distal cell fate during lung morphogenesis.
Mucenski, M.L. and Wert, S.E. and Nation, J.M. and Loudy, D.E. and Huelsken, J. and Birchmeier, W. and Morrisey, E.E. and Whitsett, J.A.
Journal of Biological Chemistry 278 (41): 40231-40238. 10 October 2003

Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation.
Naerhi, K. and Jaervinen, E. and Birchmeier, W. and Taketo, M.M. and Mikkola, M.L. and Thesleff, I.
Development 135 (6): 1019-1028. March 2008

Reconstitution of mammary gland development in vitro: Requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.
Niemann, C. and Brinkmann, V. and Spitzer, E. and Hartmann, G. and Sachs, M. and Naundorf, H. and Birchmeier, W.
Journal of Cell Biology 143 (2): 533-545. 19 October 1998

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret, C. and Miah, S.M.S. and Rota, G. and Fonta, N.P. and Wang, H. and Held, W. and Birchmeier, W. and Sexl, V. and Yang, W. and Vivier, E. and Ho, P.C. and Brossay, L. and Guarda, G.
Nature Communications 10 (1): 1444. 29 March 2019

Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas.
Otto, T. and Birchmeier, W. and Schmidt, U. and Hinke, A. and Schipper, J. and Ruebben, H. and Raz, A.
Cancer Research 54 (12): 3120-3123. 15 June 1994

The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.
Pullikuth, A. and McKinnon, E. and Schaeffer, H.J. and Catling, A.D.
Molecular and Cellular Biology 25 (12): 5119-5133. 1 June 2005

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Qi, J. and Yu, Y. and Akilli Öztürk, Ö. and Holland, J.D. and Besser, D. and Fritzmann, J. and Wulf-Goldenberg, A. and Eckert, K. and Fichtner, I. and Birchmeier, W.
Gut 65 (10): 1690-1701. October 2016

KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells.
Qi, X.T. and Li, Y.L. and Zhang, Y.Q. and Xu, T. and Lu, B. and Fang, L. and Gao, J.Q. and Yu, L.S. and Zhu, D.F. and Yang, B. and He, Q.J. and Ying, M.D.
Acta Pharmacologica Sinica 40 (4): 546-555. April 2019

miR-9-5p in nephrectomy specimens is a potential predictor of primary resistance to first-line treatment with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma.
Ralla, B. and Busch, J. and Flörcken, A. and Westermann, J. and Zhao, Z. and Kilic, E. and Weickmann, S. and Jung, M. and Fendler, A. and Jung, K.
Cancers 10 (9): 321. 10 September 2018

E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
Redmer, T. and Diecke, S. and Grigoryan, T. and Quiroga-Negreira, A. and Birchmeier, W. and Besser, D.
EMBO Reports 12 (7): 720-726. 1 July 2011

Making tubes: Step by step.
Rosario, M. and Birchmeier, W.
Developmental Cell 7 (1): 3-5. 1 July 2004

How to make tubes: signaling by the Met receptor tyrosine kinase.
Rosario, M. and Birchmeier, W.
Trends in Cell Biology 13 (6): 328-335. June 2003

The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42.
Rosario, M. and Franke, R. and Bednarski, C. and Birchmeier, W.
Journal of Cell Biology 178 (3): 503-516. 30 July 2007

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.
Rosario, M. and Schuster, S. and Juettner, R. and Parthasarathy, S. and Tarabykin, V. and Birchmeier, W.
Genes & Development 26 (15): 1743-1757. 1 August 2012

Shp-2 is dispensable for establishing T cell exhaustion and for PD-1 signaling in vivo.
Rota, G. and Niogret, C. and Dang, A.T. and Barros, C.R. and Fonta, N.P. and Alfei, F. and Morgado, L. and Zehn, D. and Birchmeier, W. and Vivier, E. and Guarda, G.
Cell Reports 23 (1): 39-49. 3 April 2018

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Ruess, D.A. and Heynen, G.J. and Ciecielski, K.J. and Ai, J. and Berninger, A. and Kabacaoglu, D. and Görgülü, K. and Dantes, Z. and Wörmann, S.M. and Diakopoulos, K.N. and Karpathaki, A.F. and Kowalska, M. and Kaya-Aksoy, E. and Song, L. and Zeeuw van der Laan, E.A. and López-Alberca, M.P. and Nazaré, M. and Reichert, M. and Saur, D. and Erkan, M.M. and Hopt, U.T. and Sainz, B. and Birchmeier, W. and Schmid, R.M. and Lesina, M. and Algül, H.
Nature Medicine 24 (7): 954-960. July 2018

The plakoglobin knock-out mouse: A paradigm for the molecular analysis of cardiac cell junction formation.
Ruiz, P. and Birchmeier, W.
Trends in Cardiovascular Medicine 8 (3): 97-101. April 1998

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
Ruiz, P. and Brinkmann, V. and Ledermann, B. and Behrend, M. and Grund, C. and Thalhammer, C. and Vogel, F. and Birchmeier, C. and Guenthert, U. and Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 135 (1): 215-225. October 1996

Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Sachs, M. and Brohmann, H. and Zechner, D. and Mueller, T. and Huelsken, J. and Walther, I. and Schaeper, U. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 150 (6): 1375-1384. 18 September 2000

Motogenic and morphogenic activity of epithelial receptor tyrosine kinases.
Sachs, M. and Weidner, K.M. and Brinkmann, V. and Walther, I. and Obermeier, A. and Ullrich, A. and Birchmeier, W.
Journal of Cell Biology 133 (5): 1095-1107. 3 June 1996

HGF/SF c-Met signaling in the epithelial-mesenchymal transition and migration of muscle progenitor cells.
Schaeper, U. and Birchmeier, W.
In: Cell Migration in Development and Disease. Wiley-VCH, Weinheim, 191-204. ISBN 3-527-30587-4 1 January 2005

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
Schaeper, U. and Gehring, N.H. and Fuchs, K.P. and Sachs, M. and Kempkes, B. and Birchmeier, W.
Journal of Cell Biology 149 (7): 1419-1432. 26 June 2000

Tyrosine kinases.
Schaeper, U. and Grossmann, K.S.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1951-1959. ISBN 3-540-44244-8 2006

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Schaeper, U. and Vogel, R. and Chmielowiec, J. and Huelsken, J. and Rosario, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104 (39): 15376-15381. 25 September 2007

Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
Scheller, M. and Huelsken, J. and Rosenbauer, F. and Taketo, M.M. and Birchmeier, W. and Tenen, D.G. and Leutz, A.
Nature Immunology 7 (10): 1037-1047. October 2006

The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
Schuetz, G. and Rosario, M. and Grimm, J. and Boeckers, T.M. and Gundelfinger, E.D. and Birchmeier, W.
Journal of Cell Biology 167 (5): 945-952. 6 December 2004

MEK Partner 1 (MP1): Regulation of oligomerization in MAP kinase signaling.
Sharma, C. and Vomastek, T. and Tarcsafalvi, A. and Catling, A.D. and Schaeffer, H.J. and Eblen, S.T. and Weber, M.J.
Journal of Cellular Biochemistry 94 (4): 708-719. 1 January 2005

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E. and McShane, E. and Cheret, C. and Walcher, J. and Müller, T. and Wulf-Goldenberg, A. and Hoelper, S. and Garratt, A.N. and Krüger, M. and Rajewsky, K. and Meijer, D. and Birchmeier, W. and Lewin, G.R. and Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung.
Shu, W. and Guttentag, S. and Wang, Z. and Andl, T. and Ballard, P. and Lu, M.M. and Piccolo, S. and Birchmeier, W. and Whitsett, J.A. and Millar, S.E. and Morrisey, E.E.
Developmental Biology 283 (1): 226-239. 1 January 2005

Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways.
Simonetti, M. and Agarwal, N. and Stösser, S. and Bali, K.K. and Karaulanov, E. and Kamble, R. and Pospisilova, B. and Kurejova, M. and Birchmeier, W. and Niehrs, C. and Heppenstall, P. and Kuner, R.
Neuron 83 (1): 104-121. 2 July 2014

Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: comparative analysis using six species of bathyergidae.
Smith, E.S.J. and Purfuerst, B. and Grigoryan, T. and Park, T.J. and Bennett, N.C. and Lewin, G.R.
Journal of Comparative Neurology 520 (12): 2785-2803. 15 August 2012

Limb development.
Soshnikova, N. and Birchmeier, W.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 1. Springer, Berlin [u.a.], 976-981. ISBN 3-540-44244-8 2006

Genetic interaction between Wnt/β-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Soshnikova, N. and Zechner, D. and Huelsken, J. and Mishina, Y. and Behringer, R.R. and Taketo, M.M. and Crenshaw, E.B. and Birchmeier, W.
Genes & Development 17 (16): 1963-1968. 1 January 2003

Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M. and Besser, D. and Benitah, S.A.
EMBO Reports 13 (1): 9-11. January 2012

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer.
Stein, U. and Arlt, F. and Walther, W. and Smith, J. and Waldman, T. and Harris, E.D. and Mertins, S.D. and Heizmann, C.W. and Allard, D. and Birchmeier, W. and Schlag, P.M. and Shoemaker, R.H.
Gastroenterology 131 (5): 1486-1500. November 2006

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Stein, U. and Walther, W. and Arlt, F. and Schwabe, H. and Smith, J. and Fichtner, I. and Birchmeier, W. and Schlag, P.M.
Nature Medicine 15 (1): 59-67. January 2009

A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl, U. and Worm, U. and Lalowski, M. and Haenig, C. and Brembeck, F.H. and Goehler, H. and Stroedicke, M. and Zenkner, M. and Schoenherr, A. and Koeppen, S. and Timm, J. and Mintzlaff, S. and Abraham, C. and Bock, N. and Kietzmann, S. and Goedde, A. and Toksoez, E. and Droege, A. and Krobitsch, S. and Korn, B. and Birchmeier, W. and Lehrach, H. and Wanker, E.E.
Cell 122 (6): 957-968. 23 September 2005

UroFors: Konstituierung eines Interessensverbundes fuer Naturwissenschaftler in der urologischen Forschung [UroFors: establishment of an interest group for natural scientists in urological research].
Stope, M.B. and Dansranjavin, T. and Erb, H. and Erdmann, K. and Fendler, A. and Hoelters, S. and Juengel, E. and Nitschke, K. and Salomo, K. and Seidel, P. and Skowron, M.A. and Wach, S. and Becker, C.
Urologe 56 (4): 515-518. April 2017

Embryonic hair follicle fate change by augmented β-catenin through Shh and Bmp signaling.
Suzuki, K. and Yamaguchi, Y. and Villacorte, M. and Mihara, K. and Akiyama, M. and Shimizu, H. and Taketo, M.M. and Nakagata, N. and Tsukiyama, T. and Yamaguchi, T.P. and Birchmeier, W. and Kato, S. and Yamada, G.
Development 136 (3): 367-372. February 2009

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta-catenin is not required for the shift.
Takeda, H. and Nagafuchi, A. and Yonemura, S. and Tsukita, S. and Behrens, J. and Birchmeier, W. and Tsukita, S.
Journal of Cell Biology 131 (6 Pt. 2): 1839-1847. December 1995

Role of Epiprofin, a zinc-finger transcription factor, in limb development.
Talamillo, A. and Delgado, I. and Nakamura, T. and de-Vega, S. and Yoshitomi, Y. and Unda, F. and Birchmeier, W. and Yamada, Y. and Ros, M.A.
Developmental Biology 337 (2): 363-374. 15 January 2010

beta-catenin-dependent and -independent effects of deltaN-plakoglobin on epidermal growth and differentiation.
Teuliere, J. and Faraldo, M.M. and Shtutman, M. and Birchmeier, W. and Huelsken, J. and Thiery, J.P. and Glukhova, M.A.
Molecular and Cellular Biology 24 (19): 8649-8661. 1 October 2004

RNF4-dependent oncogene activation by protein stabilization.
Thomas, J.J. and Abed, M. and Heuberger, J. and Novak, R. and Zohar, Y. and Beltra-Lopez, A.P. and Trausch-Azar, J.S. and Ilagan, M.X.G. and Benhamou, D. and Dittmar, G. and Kopan, R. and Birchmeier, W. and Schwartz, A.L. and Orian, A.
Cell Reports 16 (12): 3388-3400. 20 September 2016

Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a negative tumors.
Ueberham, E. and Glöckner, P. and Göhler, C. and Straub, B.K. and Teupser, D. and Schönig, K. and Braeuning, A. and Höhn, A.K. and Jerchow, B. and Birchmeier, W. and Gaunitz, F. and Arendt, T. and Sansom, O. and Gebhardt, R. and Ueberham, U.
Molecular Cancer Research 13 (2): 239-249. February 2015

Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors.
Valenti, G. and Quinn, H.M. and Heynen, G.J.J.E. and Lan, L. and Holland, J.D. and Vogel, R. and Wulf-Goldenberg, A. and Birchmeier, W.
Cancer Research 77 (8): 2134-2147. 15 April 2017

Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury.
Van Steenwinckel, J. and Schang, A.L. and Krishnan, M.L. and Degos, V. and Delahaye-Duriez, A. and Bokobza, C. and Verdonk, F. and Montane, A. and Sigaut, S. and Hennebert, O. and Lebon, S. and Schwendimann, L. and Le Charpentier, T. and Hassan-Abdi, R. and Ball, G. and Aljabar, P. and Saxena, A. and Holloway, R.K. and Birchmeier, W. and Miron, V. and Rowitch, D. and Chretien, F. and Leconte, C. and Besson, V.C. and Petretto, E.G. and Edwards, A.D. and Hagberg, H. and Soussi-Yanicostas, N. and Fleiss, B. and Gressens, P.
bioRxiv : 334359. 31 May 2018

Spatially restricted stromal Wnt signaling restrains prostate epithelial progenitor growth through direct and indirect mechanisms.
Wei, X. and Zhang, L. and Zhou, Z. and Kwon, O.J. and Zhang, Y. and Nguyen, H. and Dumpit, R. and True, L. and Nelson, P. and Dong, B. and Xue, W. and Birchmeier, W. and Taketo, M.M. and Xu, F. and Creighton, C.J. and Ittmann, M.M. and Xin, L.
Cell Stem Cell 24 (5): 753-768. 2 May 2019

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Weidner, K.M. and Dicesare, S. and Sachs, M. and Brinkmann, V. and Behrens, J. and Birchmeier, W.
Nature 384 (6605): 173-176. 14 November 1996

The Met receptor tyrosine kinase transduces motility, proliferation, andmorphogenic signals of scatter factor/ hepatocyte growth factor in epithelial cells.
Weidner, K.M. and Sachs, M. and Birchmeier, W.
Journal of Cell Biology 121 (1): 145-154. April 1993

Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.
Wend, P. and Fang, L. and Zhu, Q. and Schipper, J.H. and Loddenkemper, C. and Kosel, F. and Brinkmann, V. and Eckert, K. and Hindersin, S. and Holland, J.D. and Lehr, S. and Kahn, M. and Ziebold, U. and Birchmeier, W.
EMBO Journal 32 (14): 1977-1989. 17 July 2013

Wnt signaling in stem and cancer stem cells.
Wend, P. and Holland, J.D. and Ziebold, U. and Birchmeier, W.
Seminars in Cell & Developmental Biology 21 (8): 855-863. October 2010

Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization.
Weng, Q. and Wang, J. and Wang, J. and Wang, J. and Sattar, F. and Zhang, Z. and Zheng, J. and Xu, Z. and Zhao, M. and Liu, X. and Yang, L. and Hao, G. and Fang, L. and Lu, Q.R. and Yang, B. and He, Q.
Cell Death & Disease 9 (2): 251. 14 February 2018

The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer.
White, N.M.A. and Youssef, Y.M. and Fendler, A. and Stephan, C. and Jung, K. and Yousef, G.M.
Biological Chemistry 393 (5): 379-389. May 2012

The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling.
Wijk, N.V. and Witte, F. and Feike, A.C. and Schambony, A. and Birchmeier, W. and Mundlos, S. and Stricker, S.
Biochemical and Biophysical Research Communications 390 (2): 211-216. 11 December 2009

The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney.
Willecke, R. and Heuberger, J. and Grossmann, K. and Michos, O. and Schmidt-Ott, K. and Walentin, K. and Costantini, F. and Birchmeier, W.
Developmental Biology 360 (2): 310-307. 15 December 2011

Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach.
Winter, A. and Sigurdardottir, A.G. and DiCara, D. and Valenti, G. and Blundell, T.L. and Gherardi, E.
Molecular Cancer Therapeutics 15 (1): 3-14. January 2016

Deletion of beta-catenin impairs T cell development.
Xu, Y. and Banerjee, D. and Huelsken, J. and Birchmeier, W. and Sen, J.M.
Nature Immunology 4 (12): 1177-1182. 1 January 2003

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.
Yang, Y. and Spitzer, E. and Meyer, D. and Sachs, M. and Niemann, C. and Hartmann, G. and Weidner, K.M. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 131 (1): 215-226. October 1995

Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.
Yoshida, T. and Iwata, T. and Takai, Y. and Birchmeier, W. and Yamato, M. and Okano, T.
Genes to Cells 19 (11): 842-852. November 2014

The role of Axin2 in calvarial morphogenesis and craniosynostosis.
Yu, H.M. and Jerchow, B. and Sheu, T.J. and Liu, B. and Costantini, F. and Puzas, J.E. and Birchmeier, W. and Hsu, W.
Development 132 (8): 1995-2005. 1 January 2005

The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis.
Zatula, N. and Wiese, M. and Bunzendahl, J. and Birchmeier, W. and Perske, C. and Bleckmann, A. and Brembeck, F.H.
Oncotarget 5 (16): 6770-6787. 30 August 2014

Deciphering the function of signaling pathways by tissue specific gene modification in mice.
Zechner, D. and Soshnikova, N. and Birchmeier, W.
Zellbiologie Aktuell 30 (1): 6-8. January 2004

Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Zechner, D. and Muller, T. and Wende, H. and Walther, I. and Taketo, M.M. and Crenshaw, E.B. and Treier, M. and Birchmeier, W. and Birchmeier, C.
Developmental Biology 303 (1): 181-190. 1 March 2007

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender, A. and Huang, J. and Györfi, A.H. and Matei, A.E. and Trinh-Minh, T. and Xu, X. and Li, Y.N. and Chen, C.W. and Lin, J. and Dees, C. and Beyer, C. and Gelse, K. and Zhang, Z.Y. and Bergmann, C. and Ramming, A. and Birchmeier, W. and Distler, O. and Schett, G. and Distler, J.H.W.
Nature Communications 9 (1): 3259. 14 August 2018

Reciprocal requirements for EDA/EDAR/NF-κB and Wnt/β-catenin signaling pathways in hair follicle induction.
Zhang, Y. and Tomann, P. and Andl, T. and Gallant, N.M. and Huelsken, J. and Jerchow, B. and Birchmeier, W. and Paus, R. and Piccolo, S. and Mikkola, M.L. and Morrisey, E.E. and Overbeek, P.A. and Scheidereit, C. and Millar, S.E. and Schmidt-Ullrich, R.
Developmental Cell 17 (1): 49-61. 21 July 2009

The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer.
Zhu, Q. and Fang, L. and Heuberger, J. and Kranz, A. and Schipper, J. and Scheckenbach, K. and Oliveira Vidal, R. and Sunaga-Franze, D.Y. and Müller, M. and Wulf-Goldenberg, A. and Sauer, S. and Birchmeier, W.
Cell Reports 26 (2): 415-428. 8 January 2019

Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.
van den Akker, E. and van Dijk, T. and Parren-van Amelsvoort, M. and Grossmann, K.S. and Schaeper, U. and Toney-Earley, K. and Waltz, S.E. and Loewenberg, B. and von Lindern, M.
Blood 103 (12): 4457-4465. 1 January 2004

Birchmeier-Kohler, Carmen

Molecular aspects of mesenchymal-epithelial interactions.
Birchmeier, C. and Birchmeier, W.
Annual Review of Cell Biology 9 : 511-540. 1993

Met, metastasis, motility and more.
Birchmeier, C. and Birchmeier, W. and Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003

c-Met is essential for wound healing in the skin.
Chmielowiec, J. and Borowiak, M. and Morkel, M. and Stradal, T. and Munz, B. and Werner, S. and Wehland, J. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. and Rom, A. and Franke, V. and Imami, K. and Arrey, G. and Terne, M. and Woehler, A. and Akalin, A. and Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Targeting MET in cancer: rationale and progress.
Gherardi, E. and Birchmeier, W. and Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M. and Yu, Y. and Liang, L. and Vuralli, D. and Froehler, S. and Kuehnen, P. and Du Bois, P. and Zhang, J. and Cao, A. and Liu, Y. and Hussain, K. and Fielitz, J. and Jia, S. and Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7 (5): e602. May 2019

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T. and Stein, S. and Qi, J. and Wende, H. and Garratt, A.N. and Nave, K.A. and Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S. and Rosario, M. and Birchmeier, C. and Birchmeier, W.
Advances in Cancer Research 106 : 53-89. 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J. and Vogel, R. and Brinkmann, V. and Erdmann, B. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 148 (3): 567-578. 7 February 2000

Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
Keilhack, H. and Mueller, M. and Boehmer, S.A. and Frank, C. and Weidner, K.M. and Birchmeier, W. and Ligensa, T. and Berndt, A. and Kosmehl, H. and Gunther, B. and Mueller, T. and Birchmeier, C. and Boehmer, F.D.
Journal of Cell Biology 152 (2): 325-334. 22 January 2001

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M. and Wende, H. and Walcher, J. and Kühnemund, J. and Cheret, C. and Kempa, S. and McShane, E. and Selbach, M. and Lewin, G.R. and Birchmeier, C.
Genes & Development 32 (9-10): 645-657. 10 May 2018

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I. and Bröhl, D. and Zyrianova, T. and Isomura, A. and Czajkowski, M.T. and Kapoor, V. and Griger, J. and Ruffault, P.L. and Mademtzoglou, D. and Zammit, P.S. and Wunderlich, T. and Spuler, S. and Kühn, R. and Preibisch, S. and Wolf, J. and Kageyama, R. and Birchmeier, C.
Genes & Development 33 (9-10): 524-535. 1 May 2019

Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met.
Marx-Stoelting, P. and Borowiak, M. and Knorpp, T. and Birchmeier, C. and Buchmann, A. and Schwarz, M.
International Journal of Cancer 124 (8): 1767-1772. 15 April 2009

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. and Kirchner, M. and Uyar, B. and Cheng, J.Y. and Russo, G. and Hernandez-Miranda, L.R. and Szymborska, A. and Zauber, H. and Rudolph, I.M. and Willnow, T.E. and Akalin, A. and Haucke, V. and Gerhardt, H. and Birchmeier, C. and Kühn, R. and Krauss, M. and Diecke, S. and Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M. and Glažar, P. and Hernandez-Miranda, L.R. and Memczak, S. and Wolf, S.A. and Rybak-Wolf, A. and Filipchyk, A. and Klironomos, F. and Cerda Jara, C.A. and Fenske, P. and Trimbuch, T. and Zywitza, V. and Plass, M. and Schreyer, L. and Ayoub, S. and Kocks, C. and Kühn, R. and Rosenmund, C. and Birchmeier, C. and Rajewsky, N.
Science 357 (6357): eaam8526. 22 September 2017

Biochemical and functional characterization of the murine ros protooncogene.
Riethmacher, D. and Langholz, O. and Goedecke, S. and Sachs, M. and Birchmeier, C.
Oncogene 9 (12): 3617-3626. December 1994

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
Ruiz, P. and Brinkmann, V. and Ledermann, B. and Behrend, M. and Grund, C. and Thalhammer, C. and Vogel, F. and Birchmeier, C. and Guenthert, U. and Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 135 (1): 215-225. October 1996

Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Sachs, M. and Brohmann, H. and Zechner, D. and Mueller, T. and Huelsken, J. and Walther, I. and Schaeper, U. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 150 (6): 1375-1384. 18 September 2000

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E. and McShane, E. and Cheret, C. and Walcher, J. and Müller, T. and Wulf-Goldenberg, A. and Hoelper, S. and Garratt, A.N. and Krüger, M. and Rajewsky, K. and Meijer, D. and Birchmeier, W. and Lewin, G.R. and Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

Recessive mutations in PCBD1 cause a new type of early-onset diabetes.
Simaite, D. and Kofent, J. and Gong, M. and Rüschendorf, F. and Jia, S. and Arn, P. and Bentler, K. and Ellaway, C. and Kühnen, P. and Hoffmann, G.F. and Blau, N. and Spagnoli, F.M. and Hübner, N. and Raile, K.
Diabetes 63 (10): 3557-3564. October 2014

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.
Yang, Y. and Spitzer, E. and Meyer, D. and Sachs, M. and Niemann, C. and Hartmann, G. and Weidner, K.M. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 131 (1): 215-226. October 1995

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Zechner, D. and Muller, T. and Wende, H. and Walther, I. and Taketo, M.M. and Crenshaw, E.B. and Treier, M. and Birchmeier, W. and Birchmeier, C.
Developmental Biology 303 (1): 181-190. 1 March 2007

Blankenstein, Thomas

T cell homing to tumors detected by 3D-coordinated positron emission tomography and magnetic resonance imaging.
Agger, R. and Petersen, M.S. and Petersen, C.C. and Hansen, S.B. and Stodkilde-Jorgensen, H. and Skands, U. and Blankenstein, T. and Andersen, T.E. and Hulgaard, E.F. and Jorgensen, J.T. and Marqversen, J. and Gundersen, H.J. and Hokland, M.E.
Journal of Immunotherapy 30 (1): 29-39. January 2007

Nicotine strongly activates dendritic cell-mediated adaptive immunity - Potential role for progression of atherosclerotic lesions.
Aicher, A. and Heeschen, C. and Mohaupt, M. and Cooke, J.P. and Zeiher, A.M. and Dimmeler, S.
Circulation 107 (4): 604-611. 4 February 2003

Molecular pathways: comparing the effects of drugs and T cells to effectively target oncogenes.
Anders, K. and Blankenstein, T.
Clinical Cancer Research 19 (2): 320-326. 15 January 2013

Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.
Anders, K. and Buschow, C. and Charo, J. and Blankenstein, T.
Transgenic Research 21 (5): 1099-1107. October 2012

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K. and Buschow, C. and Herrmann, A. and Milojkovic, A. and Loddenkemper, C. and Kammertoens, T. and Daniel, P. and Yu, H. and Charo, J. and Blankenstein, T.
Cancer Cell 20 (6): 755-767. 13 December 2011

The immune system prevents recurrence of transplanted but not autochthonous antigenic tumors after oncogene inactivation therapy.
Anders, K. and Kershaw, O. and Larue, L. and Gruber, A.D. and Blankenstein, T.
International Journal of Cancer 141 (12): 2551-2561. 15 December 2017

Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome.
Babaylova, E. and Graifer, D. and Malygin, A. and Stahl, J. and Shatsky, I. and Karpova, G.
Nucleic Acids Research 37 (4): 1141-1151. March 2009

Receptor combinations hone T-cell therapy.
Blankenstein, T.
Nature Biotechnology 34 (4): 389-391. 7 April 2016

Spontaneous and therapy-induced T cell responses to cancer.
Blankenstein, T.
Arzneimittelforschung 62 (1): S9. November 2012

Do autochthonous tumors interfere with effector T cell responses?
Blankenstein, T.
Seminars in Cancer Biology 17 (4): 267-274. August 2007

The role of tumor stroma in the interaction between tumor and immune system.
Blankenstein, T.
Current Opinion in Immunology 17 (2): 180-186. 1 January 2005

The role of inflammation for tumour growth and tumour suppression.
Blankenstein, T.
In: Cancer and inflammation : Symposium on Cancer and Inflammation, held at the Novartis Foundation, London, 12-14 November 2002. Novartis Foundation Symposium ; 256 . Wiley, Hoboken, N.J., 205-210. ISBN 0-470-85510-X 23 January 2004

Genetic approaches to cancer immunotherapy.
Blankenstein, T. and Cayeux, S. and Qin, Z.
Reviews of Physiology Biochemistry and Pharmacology 129 : 1-49. 1 January 1996

Lebendvakzine gegen Tumorerkrankungen.
Blankenstein, T. and Cayeux-Pezzutto, S.
DE4431401A1. 29 February 1996

The determinants of tumour immunogenicity.
Blankenstein, T. and Coulie, P.G. and Gilboa, E. and Jaffee, E.M.
Nature Reviews Cancer 12 (4): 307-313. April 2012

Targeting cancer-specific mutations by T cell receptor gene therapy.
Blankenstein, T. and Leisegang, M. and Uckert, W. and Schreiber, H.
Current Opinion in Immunology 33 : 112-119. April 2015

Chemical carcinogens as foreign bodies and some pitfalls regarding cancer immune surveillance.
Blankenstein, T. and Qin, Z.
Advances in Cancer Research 90 : 179-207. 2003

The role of IFN-gamma in tumor transplantation immunity and inhibition of chemical carcinogenesis.
Blankenstein, T. and Qin, Z.H.
Current Opinion in Immunology 15 (2): 148-154. April 2003

Lebendvakzine zur Behandlung von Tumorerkrankungen [Live vaccine for the treatment of tumour diseases].
T. Blankenstein, S. Cayeux.
EP0777499A1 ; EP0777499B1 ; WO9605866A2 ; WO9605866A3 ; US6,039,941. 11 June 1997

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J. and Kieback, E. and Marino, S.F. and Oden, F. and Westermann, J. and Chmielewski, M. and Abken, H. and Uckert, W. and Höpken, U.E. and Rehm, A.
Molecular Therapy 26 (8): 1906-1920. 1 August 2018

Visceral leishmaniasis diagnosis and reporting delays as an obstacle to timely response actions in Nepal and India.
Boettcher, J.P. and Siwakoti, Y. and Milojkovic, A. and Siddiqui, N.A. and Gurung, C.K. and Rijal, S. and Das, P. and Kroeger, A. and Banjara, M.R.
BMC Infectious Diseases 15 (1): 43. 6 February 2015

Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates.
Briesemeister, D. and Friese, C. and Isern, C.C. and Dietz, E. and Blankenstein, T. and Thoene-Reineke, C. and Kammertoens, T.
Cytokine 60 (3): 626-633. December 2012

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis.
Briesemeister, D. and Sommermeyer, D. and Loddenkemper, C. and Loew, R. and Uckert, W. and Blankenstein, T. and Kammertoens, T.
International Journal of Cancer 128 (2): 371-378. 15 January 2011

Phase I trial of an allogeneic gene-modified tumor cell vaccine (RCC-26/CD80/IL-2) in patients with metastatic renal cell carcinoma.
Buchner, A. and Pohla, H. and Willimsky, G. and Frankenberger, B. and Frank, R. and Baur-Melnyk, A. and Siebels, M. and Stief, C.G. and Hofstetter, A. and Kopp, J. and Pezzutto, A. and Blankenstein, T. and Oberneder, R. and Schendel, D.J.
Human Gene Therapy 21 (3): 285-297. March 2010

In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance.
Buschow, C. and Charo, J. and Anders, K. and Loddenkemper, C. and Jukica, A. and Alsamah, W. and Perez, C. and Willimsky, G. and Blankenstein, T.
Journal of Immunology 184 (6): 2930-2938. 15 March 2010

In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine.
Cayeux, S. and Bukarica, B. and Buschow, C. and Charo, J. and Bunse, M. and Doerken, B. and Blankenstein, T.
Gene Therapy 14 (20): 1481-1491. October 2007

Visualizing the dynamic of adoptively transferred T cells during the rejection of large established tumors.
Charo, J. and Perez, C. and Buschow, C. and Jukica, A. and Czeh, M. and Blankenstein, T.
European Journal of Immunology 41 (11): 3187-3197. November 2011

Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X. and Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214 (11): 3417-3433. 6 November 2017

Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
Chumduri, C. and Gillissen, B. and Richter, A. and Richter, A. and Milojkovic, A. and Overkamp, T. and Mueller, A. and Pott, C. and Daniel, P.T.
Journal of Molecular Medicine 93 (5): 559-572. May 2015

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR.
Clauss, J. and Obenaus, M. and Miskey, C. and Ivics, Z. and Izsvák, Z. and Uckert, W. and Bunse, M.
Human Gene Therapy 29 (5): 569-584. May 2018

The immune response to sporadic colorectal cancer in a novel mouse model.
Czeh, M. and Loddenkemper, C. and Shalapour, S. and Schoen, C. and Robine, S. and Goldscheid, E. and Stein, H. and Schueler, T. and Willimsky, G. and Blankenstein, T.
Oncogene 29 (50): 6591-6602. 16 December 2010

Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.
Daniel, P.T. and Kroidl, A. and Cayeux, S. and Bargou, R.C. and Blankenstein, T. and Doerken, B.
Journal of Immunology 159 (8): 3808-3815. 15 October 1997

Interleukin-7 modulates anti-tumor CD8+ T cell responses via its action on host cells.
Deiser, K. and Stoycheva, D. and Bank, U. and Blankenstein, T. and Schüler, T.
PLoS ONE 11 (7): e0159690. 22 July 2016

Retroviral vectors for high-level transgene expression in T lymphocytes.
Engels, B. and Cam, H. and Schueler, T. and Indraccolo, S. and Gladow, M. and Baum, C. and Blankenstein, T. and Uckert, W.
Human Gene Therapy 14 (12): 1155-1168. 10 August 2003

Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes.
Engels, B. and Noessner, E. and Frankenberger, B. and Blankenstein, T. and Schendel, D.J. and Uckert, W.
Human Gene Therapy 16 (7): 799-810. 1 July 2005

Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken, A. and Grau, M. and Wolf, A. and Weilemann, A. and Kopp, J. and Dörken, B. and Blankenstein, T. and Pezzutto, A. and Lenz, P. and Lenz, G. and Westermann, J.
International Journal of Cancer 136 (8): 1814-1826. 15 April 2015

Influence of CD80, interleukin-2, and interleukin-7 expression in human renal cell carcinoma on the expansion, function, and survival of tumor-specific CTLs.
Frankenberger, B. and Pohla, H. and Noessner, E. and Willimsky, G. and Papier, B. and Pezzutto, A. and Kopp, J. and Oberneder, R. and Blankenstein, T. and Schendel, D.J.
Clinical Cancer Research 11 : 1733-1742. 1 January 2005

Cell-based vaccines for renal cell carcinoma: genetically-engineered tumor cells and monocyte-derived dendritic cells.
Frankenberger, B. and Regn, S. and Geiger, C. and Noessner, E. and Falk, C.S. and Pohla, H. and Javorovic, M. and Silberzahn, T. and Wilde, S. and Buchner, A. and Siebels, M. and Oberneder, R. and Willimsky, G. and Pezzutto, A. and Blankenstein, T. and Schendel, D.J.
World Journal of Urology 23 (3): 166-174. 5 July 2005

A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells.
Gavvovidis, I. and Rost, I. and Trimborn, M. and Kaiser, F.J. and Purps, J. and Wiek, C. and Hanenberg, H. and Neitzel, H. and Schindler, D.
PLoS ONE 7 (8): e40387. 30 August 2012

Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.
Gavvovidis, I. and Leisegang, M. and Willimsky, G. and Miller, N.J. and Nghiem, P. and Blankenstein, T.
Clinical Cancer Research 24 (15): 3644-3655. August 2018

Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.
Gerbitz, A. and Sukumar, M. and Helm, F. and Wilke, A. and Friese, C. and Fahrenwaldt, C. and Lehmann, F.M. and Loddenkemper, C. and Kammertoens, T. and Mautner, J. and Schmitt, C.A. and Blankenstein, T. and Bornkamm, G.W.
PLoS ONE 7 (3): e34552. 30 March 2012

Dual T cell receptor T cells with two defined specificities mediate tumor suppression via both receptors.
Gladow, M. and Uckert, W. and Blankenstein, T.
European Journal of Immunology 34 (7): 1882-1891. 1 July 2004

Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit.
Grosheva, A.S. and Zharkov, D.O. and Stahl, J. and Gopanenko, Al.V. and Tupikin, A.E. and Kabilov, M.R. and Graifer, D.M. and Karpova, G.G.
Nucleic Acids Research 45 (7): 3833-3843. 20 April 2017

Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT.
Hayashida, N. and Fujimoto, M. and Tan, K. and Prakasam, R. and Shinkawa, T. and Li, L. and Ichikawa, H. and Takii, R. and Nakai, A.
EMBO Journal 29 (20): 3459-3469. 20 October 2010

CTLA4 promotes Tyk2-STAT3 dependent B-cell oncogenecity.
Herrmann, A. and Lahtz, C. and Nagao, T. and Song, J.Y. and Chan, W.C. and Lee, H. and Yue, C. and Look, T. and Muelfarth, R. and Li, W. and Jenkins, K. and Williams, J. and Budde, L.E. and Forman, S.J. and Kwak, L.W. and Blankenstein, T. and Yu, H.
Cancer Research 77 (18): 5118-5128. 15 September 2017

Vaccine-instructed intratumoral IFN-γ enables regression of autochthonous mouse prostate cancer in allogeneic T cell transplantation.
Hess Michelini, R. and Manzo, T. and Sturmheit, T. and Basso, V. and Rocchi, M. and Freschi, M. and Listopad, J.J. and Blankenstein, T. and Bellone, M. and Mondino, A.
Cancer Research 73 (15): 4641-4652. 1 August 2013

Vaccinations with tumor cells genetically engineered to produce different cytokines: effectivity not superior to a classical adjuvant.
Hock, H. and Dorsch, M. and Kunzendorf, U. and Ueberla, K. and Qin, Z. and Diamantstein, T. and Blankenstein, T.
Cancer Research 53 (4): 714-716. 15 February 1993

A synthetic epoxyeicosatrienoic acid analog prevents the initiation of ischemic acute kidney injury.
Hoff, U. and Bubalo, G. and Fechner, M. and Blum, M. and Zhu, Y. and Pohlmann, A. and Hentschel, J. and Arakelyan, K. and Seeliger, E. and Flemming, B. and Gürgen, D. and Rothe, M. and Niendorf, T. and Manthati, V.L. and Falck, J.R. and Haase, M. and Schunck, W.H. and Dragun, D.
Acta Physiologica : e13297. 11 May 2019 (In Press)

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D. and Schön, C. and Loddenkemper, C. and Lohneis, P. and Kühl, A.A. and Sommermann, T. and Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

Tumor rejection by disturbing tumor stroma cell interactions.
Ibe, S. and Qin, Z.H. and Schueler, T. and Preiss, S. and Blankenstein, T.
Journal of Experimental Medicine 194 (11): 1549-1559. 3 December 2001

Strong immunogenic potential of a B7 retroviral expression vector: Generation of HLA-B7-restricted CTL response against selectable marker genes.
Jung, D. and Jaeger, E. and Cayeux, S. and Blankenstein, T. and Hilmes, C. and Karbach, J. and Moebius, U. and Knuth, A. and Huber, C. and Seliger, B.
Human Gene Therapy 9 : 53-62. 1 January 1998

It's the peptide-MHC affinity, stupid.
Kammertoens, T. and Blankenstein, T.
Cancer Cell 23 (4): 429-431. 15 April 2013

Making and circumventing tolerance to cancer.
Kammertoens, T. and Blankenstein, T.
European Journal of Immunology 39 (9): 2345-2353. September 2009

B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin).
Kammertoens, T. and Qin, Z. and Briesemeister, D. and Bendelac, A. and Blankenstein, T.
International Journal of Cancer 131 (7): 1499-1508. 1 October 2012

Immunotherapy: target the stroma to hit the tumor.
Kammertoens, T. and Schueler, T. and Blankenstein, T.
Trends in Molecular Medicine 11 (5): 225-231. 1 January 2005

CY15, a malignant histiocytic tumor that is phenotypically similar to immature dendritic cells.
Kammertoens, T. and Willebrand, R. and Erdmann, B. and Li, L. and Li, Y. and Engels, B. and Uckert, W. and Blankenstein, T.
Cancer Research 65 : 2560-2564. 1 January 2005

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. and Friese, C. and Arina, A. and Idel, C. and Briesemeister, D. and Rothe, M. and Ivanov, A. and Szymborska, A. and Patone, G. and Kunz, S. and Sommermeyer, D. and Engels, B. and Leisegang, M. and Textor, A. and Fehling, H.J. and Fruttiger, M. and Lohoff, M. and Herrmann, A. and Yu, H. and Weichselbaum, R. and Uckert, W. and Hübner, N. and Gerhardt, H. and Beule, D. and Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

Protein S3 fragments neighboring mRNA during elongation and termination of translation on the human ribosome.
Khairulina, Y.S. and Molotkov, M.V. and Bulygin, K.N. and Graifer, D.M. and Ven’yaminova, A.G. and Frolova, L.Y. and Stahl, J. and Karpova, G.G.
Russian Journal of Bioorganic Chemistry 34 (6): 691-697. November 2008

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer.
Kieback, E. and Charo, J. and Sommermeyer, D. and Blankenstein, T. and Uckert, W.
Proceedings of the National Academy of Sciences of the United States of America 105 (2): 623-628. 15 January 2008

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity.
Kieback, E. and Hilgenberg, E. and Stervbo, U. and Lampropoulou, V. and Shen, P. and Bunse, M. and Jaimes, Y. and Boudinot, P. and Radbruch, A. and Klemm, U. and Kühl, A.A. and Liblau, R. and Hoevelmeyer, N. and Anderton, S.M. and Uckert, W. and Fillatreau, S.
Immunity 44 (5): 1114-1126. 17 May 2016

Establishment of early lymphoid organ infrastructure in transplanted tumors mediated by local production of lymphotoxin alpha and in the combined absence of functional B and T cells.
Kim, H.J. and Kammertoens, T. and Janke, M. and Schmetzer, O. and Qin, Z. and Berek, C. and Blankenstein, T.
Journal of Immunology 172 (7): 4037-4047. 1 January 2004

Interferon-γ receptor signaling in dendritic cells restrains spontaneous proliferation of CD4(+) T cells in chronic lymphopenic mice.
Knop, L. and Frommer, C. and Stoycheva, D. and Deiser, K. and Kalinke, U. and Blankenstein, T. and Kammertoens, T. and Dunay, I.R. and Schüler, T.
Frontiers in Immunology 10 : 140. 7 February 2019

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.
Kruschinski, A. and Moosmann, A. and Poschke, I. and Norell, H. and Chmielewski, M. and Seliger, B. and Kiessling, R. and Blankenstein, T. and Abken, H. and Charo, J.
Proceedings of the National Academy of Sciences of the United States of America 105 (45): 17481-17486. 11 November 2008

T cell receptors for clinical therapy: in vitro assessment of toxicity risk.
Kunert, A. and Obenaus, M. and Lamers, C.H.J. and Blankenstein, T. and Debets, R.
Clinical Cancer Research 23 (20): 6012-6020. 15 October 2017

Ablation of TNF or lymphotoxin signaling and the frequency of spontaneous tumors in p53-deficient mice.
Kuprash, D.V. and Qin, Z. and Ito, D. and Grivennikov, S.I. and Abe, K. and Drutskaya, L.N. and Blankenstein, T. and Nedospasov, S.A.
Cancer Letters 268 (1): 70-75. 8 September 2008

A synthetic peptide homologous to functional domain of human IL-10 down-regulates expression of MHC class I and transporter associated with antigen processing 1/2 in human melanoma cells.
Kurte, M. and Lopez, M. and Aguirre, A. and Escobar, A. and Aguillon, J.C. and Charo, J. and Larsen, C.G. and Kiessling, R. and Salazar-Onfray, F.
Journal of Immunology 173 (3): 1731-1737. 1 January 2004

Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels.
Lange, C. and Schueler, T. and Blankenstein, T.
Journal of Experimental Medicine 187 (9): 1487-1493. 4 May 1998

Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice.
Lange, K. and Uckert, W. and Blankenstein, T. and Nadrowitz, R. and Bittner, C. and Renauld, J.C. and van Snick, J. and Feller, A.C. and Merz, H.
Oncogene 22 (4): 517-527. 30 January 2003

T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy.
Leisegang, M. and Turqueti-Neves, A. and Engels, B. and Blankenstein, T. and Schendel, D.J. and Uckert, W. and Noessner, E.
Clinical Cancer Research 16 (8): 2333-2343. 15 April 2010

Targeting human melanoma neoantigens by T cell receptor gene therapy.
Leisegang, M. and Kammertoens, T. and Uckert, W. and Blankenstein, T.
Journal of Clinical Investigation 126 (3): 854-858. 1 March 2016

Generation of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast-embryonic stem cell fusion.
Li, L. and Blankenstein, T.
Nature Protocols 8 (8): 1567-1582. August 2013

Transgenic mice with a diverse human T cell antigen receptor repertoire.
Li, L.P. and Lampert, J.C. and Chen, X. and Leitao, C. and Popovic, J. and Mueller, W. and Blankenstein, T.
Nature Medicine 16 (9): 1029-1034. September 2010

SV40 large T antigen-transformed human primary normal and cancerous mammary epithelial cells are phenotypically similar but can be distinguished in 3D culture with selection medium.
Li, L.P. and Willimsky, G. and Seitz, S. and Xu, Y. and Li, Y. and Schwarz, L.E. and Schlag, P.M. and Blankenstein, T.
International Journal of Cancer 123 (7): 1516-1525. 1 October 2008

CD4+ T cell-mediated HER-2/neu-specific tumor rejection in the absence of B cells.
Lindencrona, J.A. and Preiss, S. and Kammertoens, T. and Schueler, T. and Piechocki, M. and Wei, W.Z. and Seliger, B. and Blankenstein, T. and Kiessling, R.
International Journal of Cancer 109 (2): 259-264. 1 January 2004

High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann, C. and Heemskerk, B. and Kvistborg, P. and Kluin, R.J.C. and Bolotin, D.A. and Chen, X. and Bresser, K. and Nieuwland, M. and Schotte, R. and Michels, S. and Gomez-Eerland, R. and Jahn, L. and Hombrink, P. and Legrand, N. and Shu, C.J. and Mamedov, I.Z. and Velds, A. and Blank, C.U. and Haanen, J.B.A.G. and Turchaninova, M.A. and Kerkhoven, R.M. and Spits, H. and Hadrup, S.R. and Heemskerk, M.H.M. and Blankenstein, T. and Chudakov, D.M. and Bendle, G.M. and Schumacher, T.N.M.
Nature Medicine 19 (11): 1534-1541. November 2013

Fas expression by tumor stroma is required for cancer eradication.
Listopad, J.J. and Kammertoens, T. and Anders, K. and Silkenstedt, B. and Willimsky, G. and Schmidt, K. and Kuehl, A.A. and Loddenkemper, C. and Blankenstein, T.
Proceedings of the National Academy of Sciences of the United States of America 110 (6): 2276-2281. 5 February 2013

IL-10 controls ultraviolet-induced carcinogenesis in mice.
Loser, K. and Apelt, J. and Voskort, M. and Mohaupt, M. and Balkow, S. and Schwarz, T. and Grabbe, S. and Beissert, S.
Journal of Immunology 179 (1): 365-371. 1 July 2007

Die Ueberexpression von NPM-ALK in haematopoietischen Stammzellen induziert verschiedene maligne Non-Hodgkin-Lymphome in der IL-9 transgenen Maus [Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice].
Merz, H. and Lange, K. and Nadrowitz, R. and Uckert, W. and Blankenstein, T. and Feller, A.C.
Verhandlungen der Deutschen Gesellschaft fuer Pathologie 87 : 224-231. 1 January 2003

Tumor-infiltrating merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival.
Miller, N.J. and Church, C.D. and Dong, L. and Crispin, D. and Fitzgibbon, M.P. and Lachance, K. and Jing, L. and Shinohara, M. and Gavvovidis, I. and Willimsky, G. and McIntosh, M. and Blankenstein, T. and Koelle, D.M. and Nghiem, P.
Cancer Immunology Research 5 (2): 137-147. February 2017

Transduction efficiency of MLV but not of HIV-1 vectors is pseudotype dependent on human primary T lymphocytes.
Muehlebach, M.D. and Schmitt, I. and Steidl, S. and Stitz, J. and Schweizer, M. and Blankenstein, T. and Cichutek, K. and Uckert, W.
Journal of Molecular Medicine 81 (12): 801-810. December 2003

Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR.
Nassenstein, C. and Kammertoens, T. and Veres, T.Z. and Uckert, W. and Spies, E. and Fuchs, B. and Krug, N. and Braun, A.
Journal of Allergy and Clinical Immunology 120 (5): 1089-1096. November 2007

Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.
Norell, H. and Poschke, I. and Charo, J. and Wei, W.Z. and Erskine, C. and Piechocki, M.P. and Knutson, K.L. and Bergh, J. and Lidbrink, E. and Kiessling, R.
Journal of Translational Medicine 8 (1): 53. 7 June 2010

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice.
Obenaus, M. and Leitão, C. and Leisegang, M. and Chen, X. and Gavvovidis, I. and van der Bruggen, P. and Uckert, W. and Schendel, D.J. and Blankenstein, T.
Nature Biotechnology 33 (4): 402-407. April 2015

CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions.
Ohl, L. and Mohaupt, M. and Czeloth, N. and Hintzen, G. and Kiafard, Z. and Zwirner, J. and Blankenstein, T. and Henning, G. and Foerster, R.
Immunity 21 (2): 279-288. 1 August 2004

Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer.
Penter, L. and Dietze, K. and Ritter, J. and Lammoglia Cobo, M.F. and Garmshausen, J. and Aigner, F. and Bullinger, L. and Hackstein, H. and Wienzek-Lischka, S. and Blankenstein, T. and Hummel, M. and Dornmair, K. and Hansmann, L.
OncoImmunology 8 (6): e1586409. 24 March 2019

Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts.
Perez, C. and Jukica, A. and Listopad, J.J. and Anders, K. and Kühl, A.A. and Loddenkemper, C. and Blankenstein, T. and Charo, J.
International Journal of Cancer 137 (2): 359-371. 15 July 2014

Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells.
Pinto, S. and Sommermeyer, D. and Michel, C. and Wilde, S. and Schendel, D. and Uckert, W. and Blankenstein, T. and Kyewski, B.
European Journal of Immunology 44 (9): 2811-2821. September 2014

High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients after tumor cell vaccination.
Pohla, H. and Buchner, A. and Stadlbauer, B. and Frankenberger, B. and Stevanovic, S. and Walter, S. and Frank, R. and Schwachula, T. and Olek, S. and Kopp, J. and Willimsky, G. and Stief, C.G. and Hofstetter, A. and Pezzutto, A. and Blankenstein, T. and Oberneder, R. and Schendel, D.J.
Molecular Medicine 18 : 1499-1508. 8 February 2013

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.
Poncette, L. and Chen, X. and Lorenz, F.K.M. and Blankenstein, T.
Journal of Clinical Investigation 129 (1): 324-335. 2 January 2019

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic, J. and Li, L.P. and Kloetzel, P.M. and Leisegang, M. and Uckert, W. and Blankenstein, T.
Blood 118 (4): 946-954. 28 July 2011

Tumor-induced antibodies resemble the response to tissue damage.
Preiss, S. and Kammertoens, T. and Lampert, C. and Willimsky, G. and Blankenstein, T.
International Journal of Cancer 115 (3): 456-462. 1 January 2005

Methods for use of cytokine gene-modified tumor cells in immunotherapy of cancer.
Qin, Z. and Blankenstein, T.
Methods in Molecular Medicine 7 : 339-348. 1997

Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis.
Qin, Z. and Krueger-Krasagakes, S. and Kunzendorf, U. and Hock, H. and Diamantstein, T. and Blankenstein, T.
Journal of Experimental Medicine 178 (1): 355-360. 1 July 1993

Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte- macrophage colony-stimulating factor gene-modified tumor cells.
Qin, Z. and Noffz, G. and Mohaupt, M. and Blankenstein, T.
Journal of Immunology 159 (2): 770-776. 15 July 1997

A cancer immunosurveillance controversy.
Qin, Z.H. and Blankenstein, T.
Nature Immunology 5 (1): 3-4. 1 January 2004

A critical requirement of interferon gamma-mediated angiostasis for tumor rejection by CD8T cells.
Qin, Z.H. and Schwartzkopff, J. and Pradera, F. and Kammertoens, T. and Seliger, B. and Pircher, H. and Blankenstein, T.
Cancer Research 63 (14): 4095-4100. 1 January 2003

Inhibition of methylcholanthrene-induced carcinogenesis by an interferon gamma receptor-dependent foreign body reaction.
Qin, Z. and Kim, H.J. and Hemme, J. and Blankenstein, T.
Journal of Experimental Medicine 195 (11): 1479-1490. 3 June 2002

Interleukin 10 transfected into Chinese hamster ovary cells prevents tumor growth and macrophage infiltration.
Richter, G. and Krueger-Krasagakes, S. and Hein, G. and Huels, C. and Schmitt, E. and Diamantstein, T. and Blankenstein, T.
Cancer Research 53 (18): 4134-4137. 15 September 1993

Induction of PSA-specific CTLs and anti-tumor immunity by a genetic prostate cancer vaccine.
Roos, A.K. and Pavlenko, M. and Charo, J. and Egevad, L. and Pisa, P.
Prostate 62 (3): 217-223. 1 January 2005

IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis.
Rothe, M. and Quarcoo, D. and Chashchina, A.A. and Bozrova, S.V. and Qin, Z. and Nedospasov, S.A. and Blankenstein, T. and Kammertoens, T. and Drutskaya, M.S.
Cancer Medicine 2 (6): 815-825. December 2013

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
Schmidt, K. and Zilio, S. and Schmollinger, J.C. and Bronte, V. and Blankenstein, T. and Willimsky, G.
Blood 121 (10): 1740-1748. 7 March 2013

ERAP1-dependent antigen cross-presentation determines efficacy of adoptive T cell therapy in mice.
Schmidt, K. and Keller, C. and Kühl, A.A. and Textor, A. and Seifert, U. and Blankenstein, T. and Willimsky, G. and Kloetzel, P.M.
Cancer Research 78 (12): 3243-3254. June 2018

Cutting edge: CD8+ effector T cells reject tumors by direct antigen recognition but indirect action on host cells.
Schueler, T. and Blankenstein, T.
Journal of Immunology 170 (9): 4427-4431. 1 May 2003

Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8+ T cells.
Schueler, T. and Kammertoens, T. and Preiss, S. and Debs, P. and Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 194 (12): 1767-1775. 17 December 2001

Tumor rejection by modulation of tumor stromal fibroblasts.
Schueler, T. and Koernig, S. and Blankenstein, T.
Journal of Experimental Medicine 198 (10): 1487-1493. 17 November 2003

T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice.
Schueler, T. and Qin, Z. and Ibe, S. and Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 189 (5): 803-810. 1 March 1999

Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo.
Shalapour, S. and Deiser, K. and Sercan, O. and Tuckermann, J. and Minnich, K. and Willimsky, G. and Blankenstein, T. and Haemmerling, G.J. and Arnold, B. and Schueler, T.
European Journal of Immunology 40 (9): 2391-2400. September 2010

Leukemia-associated genetic aberrations in mesenchymal stem cells of children with acute lymphoblastic leukemia.
Shalapour, S. and Eckert, C. and Seeger, K. and Pfau, M. and Prada, J. and Henze, G. and Blankenstein, T. and Kammertoens, T.
Journal of Molecular Medicine 88 (3): 249-265. March 2010

Molecular contacts of ribose-phosphate backbone of mRNA with human ribosome.
Sharifulin, D.E. and Grosheva, A.S. and Bartuli, Y.S. and Malygin, A.A. and Meschaninova, M.I. and Ven'yaminova, A.G. and Stahl, J. and Graifer, D.M. and Karpova, G.G.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1849 (8): 930-939. August 2015

Designer T cells by T cell receptor replacement.
Sommermeyer, D. and Neudorfer, J. and Weinhold, M. and Leisegang, M. and Engels, B. and Noessner, E. and Heemskerk, M.H. and Charo, J. and Schendel, D.J. and Blankenstein, T. and Bernhard, H. and Uckert, W.
European Journal of Immunology 36 (11): 3052-3059. November 2006

Necrotic death but not irradiation abolishes costimulation of T-cell effector functions and survival by CD80-expressing tumor cells.
Staerck, L. and Scholz, C. and Blankenstein, T. and Doerken, B. and Daniel, P.T.
International Journal of Cancer 116 (1): 78-86. 1 January 2005

Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets.
Stelljes, M. and Strothotte, R. and Pauels, H.G. and Poremba, C. and Milse, M. and Specht, C. and Albring, J. and Bisping, G. and Scheffold, C. and Kammertoens, T. and Oelmann, E. and Silling, G. and Berdel, W.E. and Kienast, J.
Blood 104 (4): 1210-1216. 1 January 2004

A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo.
Szyska, M. and Herda, S. and Althoff, S. and Heimann, A. and Russ, J. and D'Abundo, D. and Dang, T.M. and Durieux, I. and Dörken, B. and Blankenstein, T. and Na, I.K.
Cancer Immunology Research 6 (1): 110-120. January 2018

Efficacy of CAR T-cell therapy in large tumors relies upon stromal targeting by IFNγ.
Textor, A. and Listopad, J.J. and Wührmann, L.L. and Perez, C. and Kruschinski, A. and Chmielewski, M. and Abken, H. and Blankenstein, T. and Charo, J.
Cancer Research 74 (23): 6796-6805. 1 December 2014

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Textor, A. and Schmidt, K. and Kloetzel, P.M. and Weißbrich, B. and Perez, C. and Charo, J. and Anders, K. and Sidney, J. and Sette, A. and Schumacher, T.N.M. and Keller, C. and Busch, D.H. and Seifert, U. and Blankenstein, T.
Journal of Experimental Medicine 213 (11): 2333-2348. 17 October 2016

Construction of a T cell line-based packaging cell line for the production of T cell receptor retroviruses by enriching of Cd3 expressing cells.
Uckert, W. and Blankenstein, T.
WO0700318. 4 January 2007

Gentherapie mit T-Zellrezeptor modifizierten Zellen.
Uckert, W. and Blankenstein, T.
BioForum 28 (3): 27-30. 20 May 2005

Active MAC-1 (CD11b/CD18) on DC is inhibitory for full T cell activation.
Varga, G. and Balkow, S. and Wild, M.K. and Stadtbaeumer, A. and Krummen, M. and Rothoeft, T. and Higuchi, T. and Beissert, S. and Wethmar, K. and Scharffetter-Kochanek, K. and Vestweber, D. and Grabbe, S.
Blood 109 (2): 661-669. 15 January 2007

HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice.
Vertuani, S. and Triulzi, C. and Roos, A.K. and Charo, J. and Norell, H. and Lemonnier, F. and Pisa, P. and Seliger, B. and Kiessling, R.
Cancer Immunology Immunotherapy 58 (5): 653-664. May 2009

MHCII-independent CD4(+) T cells protect injured CNS neurons via IL-4.
Walsh, J.T. and Hendrix, S. and Boato, F. and Smirnov, I. and Zheng, J. and Lukens, J.R. and Gadani, S. and Hechler, D. and Gölz, G. and Rosenberger, K. and Kammertöns, T. and Vogt, J. and Vogelaar, C. and Siffrin, V. and Radjavi, A. and Fernandez-Castaneda, A. and Gaultier, A. and Gold, R. and Kanneganti, T.D. and Nitsch, R. and Zipp, F. and Kipnis, J.
Journal of Clinical Investigation 125 (2): 699-714. 2 February 2015

Rapid method of total RNA mini-preparation from eucaryotic cells.
Walther, W. and Stein, U. and Uckert, W.
Nucleic Acids Research 21 (7): 1682. 11 April 1993

Dual T cell receptor expressing CD8+ T cells with tumor- and self-specificity can inhibit tumor growth without causing severe autoimmunity.
Weinhold, M. and Sommermeyer, D. and Uckert, W. and Blankenstein, T.
Journal of Immunology 179 (8): 5534-5542. 15 October 2007

Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study.
Westermann, J. and Floercken, A. and Willimsky, G. and van Lessen, A. and Kopp, J. and Takvorian, A. and Joehrens, K. and Lukowsky, A. and Schoenemann, C. and Sawitzki, B. and Pohla, H. and Frank, R. and Doerken, B. and Schendel, D.J. and Blankenstein, T. and Pezzutto, A.
Gene Therapy 18 (4): 354-363. April 2011

Flt-3 ligand as adjuvant for DNA vaccination augments immune responses but does not skew TH1/TH2 polarization.
Westermann, J. and Nguyen-Hoai, T. and Mollweide, A. and Richter, G. and Schmetzer, O. and Kim, H.J. and Blankenstein, T. and Doerken, B. and Pezzutto, A.
Gene Therapy 11 (13): 1048-1056. 1 January 2004

Migration of immature mouse DC across resting endothelium is mediated by ICAM-2 but independent of beta2-integrins and murine DC-SIGN homologues.
Wethmar, K. and Helmus, Y. and Luehn, K. and Jones, C. and Laskowska, A. and Varga, G. and Grabbe, S. and Lyck, R. and Engelhardt, B. and Bixel, M.G. and Butz, S. and Loser, K. and Beissert, S. and Ipe, U. and Vestweber, D. and Wild, M.K.
European Journal of Immunology 36 (10): 2781-2794. October 2006

The adaptive immune response to sporadic cancer.
Willimsky, G. and Blankenstein, T.
Immunological Reviews 220 (1): 102-112. December 2007

Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance.
Willimsky, G. and Blankenstein, T.
Nature 437 (7055): 141-146. 1 September 2005

Adoptive T-cell therapy to treat liver cancer: Is the liver microenvironment key?
Willimsky, G. and Protzer, U. and Knolle, P. and Heikenwalder, M.
Oncotarget 4 (8): 1117-1118. August 2013

Virus-induced hepatocellular carcinomas cause antigen-specific local tolerance.
Willimsky, G. and Schmidt, K. and Loddenkemper, C. and Gellermann, J. and Blankenstein, T.
Journal of Clinical Investigation 123 (3): 1032-1043. 1 March 2013

Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness.
Willimsky, G. and Czeh, M. and Loddenkemper, C. and Gellermann, J. and Schmidt, K. and Wust, P. and Stein, H. and Blankenstein, T.
Journal of Experimental Medicine 205 (7): 1687-1700. 7 July 2008

CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis.
Wolf, S.A. and Steiner, B. and Akpinarli, A. and Kammertoens, T. and Nassenstein, C. and Braun, A. and Blankenstein, T. and Kempermann, G.
Journal of Immunology 182 (7): 3979-3984. 1 April 2009

Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus.
Wolf, S.A. and Steiner, B. and Wengner, A.M. and Lipp, M. and Kammertoens, T. and Kempermann, G.
FASEB Journal 23 (9): 3121-3128. September 2009

Long-term suppression of tumor growth by TNF requires a Stat1- and IFN regulatory factor 1-dependent IFN-γ pathway but not IL-12 or IL-18.
Wu, T.H. and Pabin, C.N. and Qin, Z.H. and Blankenstein, T. and Philip, M. and Dignam, J. and Schreiber, K. and Schreiber, H.
Journal of Immunology 172 (5): 3243-3251. 1 January 2004

Fibroblast-specific protein 1/S100A4-positive cells prevent carcinoma through collagen production and encapsulation of carcinogens.
Zhang, J and Chen, L and Liu, X and Kammertoens, T. and Blankenstein, T. and Qin, Z.
Cancer Research 73 (9): 2770-2781. 1 May 2013

Tumor necrosis factor receptor 2-mediated tumor suppression is nitric oxide dependent and involves angiostasis.
Zhao, X. and Mohaupt, M. and Jiang, J. and Liu, S. and Li, B. and Qin, Z.
Cancer Research 67 (9): 4443-4450. 1 May 2007

Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies.
Çakmak-Görür, N. and Radke, J. and Rhein, S. and Schumann, E. and Willimsky, G. and Heppner, F.L. and Blankenstein, T. and Pezzutto, A.
Leukemia 33 (4): 1039-1043. April 2019

Calkhoven, Cornelis F.

Analysis of translation initiation using a translation control reporter system.
Wiesenthal, V. and Leutz, A. and Calkhoven, C.F.
Nature Protocols 1 (3): 1531-1537. 9 November 2006

A translation control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell.
Wiesenthal, V. and Leutz, A. and Calkhoven, C.F.
Nucleic Acids Research 34 (3): e23. 10 February 2006

Cardoso, Cristina

Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.
Gupta, S. and Hoepner, S. and Rupp, B. and Guenther, S. and Dickhaut, K. and Agarwal, N. and Cardoso, M.C. and Kuehne, R. and Wiesmueller, K.H. and Jung, G. and Falk, K. and Roetzschke, O.
PLoS ONE 3 (3): e1814. 19 March 2008

A fraction of MCM 2 proteins remain associated with replication foci during a major part of S phase.
Masata, M. and Juda, P. and Raska, O. and Cardoso, M.C. and Raska, I.
Folia Biologica Prague 57 (1): 3-11. 2011

Chekulaeva, Marina (BIMSB)

Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63 (6): 918-925. 15 September 2016

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. and Rom, A. and Franke, V. and Imami, K. and Arrey, G. and Terne, M. and Woehler, A. and Akalin, A. and Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution.
Mauri, M. and Kirchner, M. and Aharoni, R. and Ciolli Mattioli, C. and van den Bruck, D. and Gutkovitch, N. and Modepalli, V. and Selbach, M. and Moran, Y. and Chekulaeva, M.
Nucleic Acids Research 45 (2): 938-950. 25 January 2017

Translation of circRNAs.
Pamudurti, NR. and Bartok, O. and Jens, M. and Ashwal-Fluss, R. and Stottmeister, C. and Ruhe, L. and Hanan, M. and Wyler, E. and Perez-Hernandez, D. and Ramberger, E. and Shenzis, S. and Samson, M. and Dittmar, G. and Landthaler, M. and Chekulaeva, M. and Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Chen, Wei (BIMSB/BIH)

Identification and functional characterization of hypoxia-induced endoplasmic reticulum stress regulating lncRNA (HypERlnc) in pericytes.
Bischoff, F.C. and Werner, A. and John, D. and Boeckel, J.-N. and Melissari, M.-T. and Grote, P. and Glaser, S.F. and Demolli, S. and Uchida, S. and Michalik, K.M. and Meder, B. and Katus, H.A. and Haas, J. and Chen, W. and Pullamsetti, S.S. and Seeger, W. and Zeiher, A.M. and Dimmeler, S. and Zehendner, C.M.
Circulation Research 121 (4): 368-375. 4 August 2017

Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N. and Perret, M.F. and Glaser, S.F. and Seeger, T. and Heumüller, A.W. and Chen, W. and John, D. and Kokot, K.E. and Katus, H.A. and Haas, J. and Lackner, M.K. and Kayvanpour, E. and Grabe, N. and Dieterich, C. and von Haehling, S. and Ebner, N. and Hünecke, S. and Leuschner, F. and Fichtlscherer, S. and Meder, B. and Zeiher, A.M. and Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126 : 13-22. January 2019

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B. and Eichelbaum, K. and Sadewasser, A. and Wang, X. and Husic, I. and Paki, K. and Hergeselle, M. and Vetter, B. and Hou, J. and Chen, W. and Wiebusch, L. and Meyer, I.M. and Wolff, T. and Selbach, M.
bioRxiv : 438176. 8 October 2018

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Buonocore, F. and Kuehnen, P. and Suntharalingham, J.P. and Del Valle, I. and Digweed, M. and Stachelscheid, H. and Khajavi, N. and Didi, M. and Brady, A.F. and Blankenstein, O. and Procter, A.M. and Dimitri, P. and Wales, J.K.H. and Ghirri, P. and Knoebl, D. and Strahm, B. and Erlacher, M. and Wlodarski, M.W. and Chen, W. and Kokai, G.K. and Anderson, G. and Morrogh, D. and Moulding, D.A. and McKee, S. A. and Niemeyer, C.M. and Grueters, A. and Achermann, J.C.
Journal of Clinical Investigation 127 (5): 1700-1713. 1 May 2017

Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.
Cui, H. and Bansal, V. and Grunert, M. and Malecova, B. and Dall Agnese, A. and Latella, L. and Gatto, S. and Ryan, T. and Schulz, K. and Chen, W. and Dorn, C. and Puri, P.L. and Sperling, S.R.
PLoS ONE 12 (6): e0179464. 13 June 2017

Epigenomic profiling of human CD4(+) T cells supports a linear differentiation model and highlights molecular regulators of memory development.
Durek, P. and Nordström, K. and Gasparoni, G. and Salhab, A. and Kressler, C. and de Almeida, M. and Bassler, K. and Ulas, T. and Schmidt, F. and Xiong, J. and Glažar, P. and Klironomos, F. and Sinha, A. and Kinkley, S. and Yang, X. and Arrigoni, L. and Amirabad, A.. and Ardakani, F.B. and Feuerbach, L. and Gorka, O. and Ebert, P. and Müller, F. and Li, N. and Frischbutter, S. and Schlickeiser, S. and Cendon, C. and Fröhler, S. and Felder, B. and Gasparoni, N. and Imbusch, C.D. and Hutter, B. and Zipprich, G. and Tauchmann, Y. and Reinke, S. and Wassilew, G. and Hoffmann, U. and Richter, A.S. and Sieverling, L. and Chang, H.D. and Syrbe, U. and Kalus, U. and Eils, J. and Brors, B. and Manke, T. and Ruland, J. and Lengauer, T. and Rajewsky, N. and Chen, W. and Dong, J. and Sawitzki, B. and Chung, H.R. and Rosenstiel, P. and Schulz, M.H. and Schultze, J.L. and Radbruch, A. and Walter, J. and Hamann, A. and Polansky, J.K.
Immunity 45 (5): 1148-1161. 15 November 2016

Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells.
Gogol-Döring, A. and Ammar, I. and Gupta, S. and Bunse, M. and Miskey, C. and Chen, W. and Uckert, W. and Schulz, T.F. and Izsvák, Z. and Ivics, Z.
Molecular Therapy 24 (3): 592-606. March 2016

Genetics of intellectual disability in consanguineous families.
Hu, H. and Kahrizi, K. and Musante, L. and Fattahi, Z. and Herwig, R. and Hosseini, M. and Oppitz, C. and Abedini, S.S. and Suckow, V. and Larti, F. and Beheshtian, M. and Lipkowitz, B. and Akhtarkhavari, T. and Mehvari, S. and Otto, S. and Mohseni, M. and Arzhangi, S. and Jamali, P. and Mojahedi, F. and Taghdiri, M. and Papari, E. and Soltani Banavandi, M.J. and Akbari, S. and Tonekaboni, S.H. and Dehghani, H. and Ebrahimpour, M.R. and Bader, I. and Davarnia, B. and Cohen, M. and Khodaei, H. and Albrecht, B. and Azimi, S. and Zirn, B. and Bastami, M. and Wieczorek, D. and Bahrami, G. and Keleman, K. and Vahid, L.N. and Tzschach, A. and Gärtner, J. and Gillessen-Kaesbach, G. and Varaghchi, J.R. and Timmermann, B. and Pourfatemi, F. and Jankhah, A. and Chen, W. and Nikuei, P. and Kalscheuer, V.M. and Oladnabi, M. and Wienker, T.F. and Ropers, H.H. and Najmabadi, H.
Molecular Psychiatry 4 January 2018 (In Press)

Long noncoding RNA lISPR1 is required for S1P signaling and endothelial cell function.
Josipovic, I. and Pflueger, B. and Fork, C. and Vasconez, A.E. and Oo, J.A. and Hitzel, J. and Seredinski, S. and Gamen, E. and Heringdorf, D.M.Z. and Chen, W. and Looso, M. and Pullamsetti, S.S. and Brandes, R.P. and Leisegang, M.S.
Journal of Molecular and Cellular Cardiology 116 : 57-68. March 2018

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M. and Perrod, C. and Hoogenkamp, M. and Ghani, S. and Assi, S. and Heinz, S. and Wilson, N.K. and Follows, G. and Schoenheit, J. and Vockentanz, L. and Mosamam, A. and Chen, W. and Tenen, D.G. and Westhead, D.R. and Goettgens, B. and Bonifer, C. and Rosenbauer, F.
Blood 117 (10): 2827-2838. 10 March 2011

The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.
Leisegang, M.S. and Gu, L. and Preussner, J. and Günther, S. and Hitzel, J. and Ratiu, C. and Weigert, A. and Chen, W. and Schwarz, E.C. and Looso, M. and Fork, C. and Brandes, R.P.
FEBS Letters 593 (5): 487-498. March 2019

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.
Löber, U. and Hobbs, M. and Dayaram, A. and Tsangaras, K. and Jones, K. and Alquezar-Planas, D.E. and Ishida, Y. and Meers, J. and Mayer, J. and Quedenau, C. and Chen, W. and Johnson, R.N. and Timms, P. and Young, P.R. and Roca, A.L. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): 8609-8614. 21 August 2018

An integrated understanding of the molecular mechanisms how adipose tissue metabolism affects long-term body weight maintenance.
Mai, K. and Li, L. and Wiegand, S. and Brachs, M. and Leupelt, V. and Ernert, A. and Kühnen, P. and Hübner, N. and Robinson, P. and Chen, W. and Krude, H. and Spranger, J.
Diabetes 68 (1): 57-65. 1 January 2019

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N. and Kolesnichenko, M. and Beaudette, P. and Popp, O. and Uyar, B. and Sun, W. and Tufan, A.B. and Perder, B. and Akalin, A. and Chen, W. and Mertins, P. and Dittmar, G. and Hinz, M. and Scheidereit, C.
EMBO Journal 37 (24): e98658. 14 December 2018

Identification of the elementary structural units of the DNA damage response.
Natale, F. and Rapp, A. and Yu, W. and Maiser, A. and Harz, H. and Scholl, A. and Grulich, S. and Anton, T. and Hoerl, D. and Chen, W. and Durante, M. and Taucher-Scholz, G. and Leonhardt, H. and Cardoso, M.C.
Nature Communications 8 : 15760. 12 June 2017

Pontine tegmental cap dysplasia in an extremely preterm infant and review of the literature.
Picker-Minh, S. and Hartenstein, S. and Proquitte, H. and Froehler, S. and Raile, V. and Kraemer, N. and Apeshiotis, S. and Leipoldt, M. and Kalache, K.D. and Morris-Rosendahl, D. and Boltshauser, E. and Chen, W. and Kaindl, A.M.
Journal of Child Neurology 32 (3): 334-340. March 2017

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt, F. and Gasparoni, N. and Gasparoni, G. and Gianmoena, K. and Cadenas, C. and Polansky, J.K. and Ebert, P. and Nordstroem, K. and Barann, M. and Sinha, A. and Froehler, S. and Xiong, J. and Amirabad, A.D. and Ardakani, F.B. and Hutter, B. and Zipprich, G. and Felder, B. and Eils, J. and Brors, B. and Chen, W. and Hengstler, J.G. and Hamann, A. and Lengauer, T. and Rosenstiel, P. and Walter, J. and Schulz, M.H.
bioRxiv : 081935. 19 October 2016

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt, F. and Gasparoni, N. and Gasparoni, G. and Gianmoena, K. and Cadenas, C. and Polansky, J.K. and Ebert, P. and Nordstroem, K. and Barann, M. and Sinha, A. and Froehler, S. and Xiong, J. and Dehghani Amirabad, A. and Behjati Ardakani, F. and Hutter, B. and Zipprich, G. and Felder, B. and Eils, J. and Brors, B. and Chen, W. and Hengstler, J.G. and Hamann, A. and Lengauer, T. and Rosenstiel, P. and Walter, J. and Schulz, M.H.
Nucleic Acids Research 45 (1): 54-66. 9 January 2017

Comprehensive small RNA-Seq of adeno-associated virus (AAV)-infected human cells detects patterns of novel, non-coding AAV RNAs in the absence of cellular miRNA regulation.
Stutika, C. and Mietzsch, M. and Gogol-Doering, A. and Weger, S. and Sohn, M. and Chen, W. and Heilbronn, R.
PLoS ONE 11 (9): e0161454. 9 September 2016

Metabolic labeling of newly synthesized RNA with 4sU to in parallel assess RNA transcription and decay.
Sun, W. and Chen, W.
Methods in Molecular Biology 1720 : 25-34. 2018

Pervasive allele-specific regulation on RNA decay in hybrid mice.
Sun, W. and Gao, Q. and Schaefke, B. and Hu, Y. and Chen, W.
Life Science Alliance 1 (2): e201800052. May 2018

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. and Xie, G. and Singh, M. and Ghanbarian, A.T. and Raskó, T. and Szvetnik, A. and Cai, H. and Besser, D. and Prigione, A. and Fuchs, N.V. and Schumann, G.G. and Chen, W. and Lorincz, M.C. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation.
Xiao, M.S. and Zhang, B. and Li, Y.S. and Gao, Q. and Sun, W. and Chen, W.
Molecular Systems Biology 12 (12): 890. 8 December 2016

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
Yang, J.Y. and Deng, X.Y. and Li, Y.S. and Ma, X.C. and Feng, J.X. and Yu, B. and Chen, Y. and Luo, Y.L. and Wang, X. and Chen, M.L. and Fang, Z.X. and Zheng, F.X. and Li, Y.P. and Zhong, Q. and Kang, T.B. and Song, L.B. and Xu, R.H. and Zeng, M.S. and Chen, W. and Zhang, H. and Xie, W. and Gao, S.
Nature Communications 9 (1): 1165. 21 March 2018

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression.
Zhang, B. and Calado, D.P. and Wang, Z. and Froehler, S. and Koechert, K. and Qian, Y. and Koralov, S.B. and Schmidt-Supprian, M. and Sasaki, Y. and Unitt, C. and Rodig, S. and Chen, W. and Dalla-Favera, R. and Alt, F.W. and Pasqualucci, L. and Rajewsky, K.
Cell Reports 11 (5): 715-726. 5 May 2015

Damaschun, Gregor

Multimodal particle size distribution or fractal surface of acrylic acid copolymer nanoparticles: A small-angle X-ray scattering study using direct Fourier and indirect maximum entropy methods.
Mueller, J.J. and Hansen, S. and Lukowski, G. and Gast, K.
Journal of Applied Crystallography 28 (Pt 6): 774-781. 1 December 1995

AKIMA interpolation: A tool used in direct slit-length desmearing procedures of non-frequency- limited X-ray scattering curves.
Mueller, J.J. and Mueller, E.C. and Gernat, C. and Kroeber, R.
Journal of Applied Crystallography 28 (Pt 1): 38-42. 1 February 1995

Daniel, Peter

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K. and Buschow, C. and Herrmann, A. and Milojkovic, A. and Loddenkemper, C. and Kammertoens, T. and Daniel, P. and Yu, H. and Charo, J. and Blankenstein, T.
Cancer Cell 20 (6): 755-767. 13 December 2011

Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Arnold, W. and Daniel, P.T. and Mapara, M.Y. and Grinstein, E. and Royer, H.D. and Doerken, B.
Journal of Experimental Medicine 183 (3): 1205-1213. 1 March 1996

Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Mapara, M.Y. and Daniel, P.T. and Arnold, W. and Dietel, M. and Guski, H. and Feller, A. and Royer, H.D. and Doerken, B.
Journal of Clinical Investigation 97 (11): 2651-2659. 1 June 1996

DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis.
Bhonde, M.R. and Hanski, M.L. and Budczies, J. and Cao, M. and Gillissen, B. and Moorthy, D. and Simonetta, F. and Scheruebl, H. and Truss, M. and Hagemeier, C. and Mewes, H.W. and Daniel, P.T. and Zeitz, M. and Hanski, C.
Journal of Biological Chemistry 281 : 8675-8685. 31 March 2006

The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein.
Bhonde, M.R. and Hanski, M.L. and Magrini, R. and Moorthy, D. and Mueller, A. and Sausville, E.A. and Kohno, K. and Wiegand, P. and Daniel, P.T. and Zeitz, M. and Hanski, C.
Oncogene 24 : 148-156. 6 January 2005

Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.
Bhonde, M.R. and Hanski, M.L. and Notter, M. and Gillissen, B.F. and Daniel, P.T. and Zeitz, M. and Hanski, C.
Oncogene 25 : 165-175. 12 January 2006

Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia.
Bosanquet, A.G. and Sturm, I. and Wieder, T. and Essmann, F. and Bosanquet, M.I. and Head, F.J. and Doerken, B. and Daniel, P.T.
Leukemia 16 (6): 1035-1044. June 2002

Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.
Burek, M. and Maddika, S. and Burek, C.J. and Daniel, P.T. and Schulze-Osthoff, K. and Los, M.
Oncogene 25 : 2213-2222. 6 April 2006

Bax-dependent regulation of Bak by voltage-dependent anion channel 2.
Chandra, D. and Choy, G. and Daniel, P.T. and Tang, D.G.
Journal of Biological Chemistry 280 : 19051-19061. 1 January 2005

Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death.
Chandra, D. and Choy, G. and Deng, X. and Bhatia, B. and Daniel, P. and Tang, D.G.
Molecular and Cellular Biology 24 : 6592-6607. 1 January 2004

Immediate effects of reversible HTLV-I tax function: T-cell activation and apoptosis.
Chlichlia, K. and Moldenhauer, G. and Daniel, P.T. and Busslinger, M. and Gazzalo, L. and Schirrmacher, V. and Khazaie, K.
Oncogene 10 (2): 269-277. 19 January 1995

Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
Chumduri, C. and Gillissen, B. and Richter, A. and Richter, A. and Milojkovic, A. and Overkamp, T. and Mueller, A. and Pott, C. and Daniel, P.T.
Journal of Molecular Medicine 93 (5): 559-572. May 2015

Molekulare Grundlagen der zielgerichteten Tumortherapie [The molecular bases of targeted tumor therapy].
Daniel, P.
Onkologe 13 (1): 8-19. January 2007

Zellzyklus und Apoptose.
Daniel, P.T.
In: Molekularmedizinische Grundlagen von haematologischen Neoplasien. Molekulare Medizin . Springer, Berlin [u.a.], 130-184. ISBN 3-540-41640-4 1 January 2003

Grundlagen der molekularen Diagnostik und Therapie maligner Tumoren [Basics of molecular diagnostics and therapy of malignant tumors].
Daniel, P.T. and Doerken, B.
Internist 46 (8): 835-846. 12 July 2005

Apoptolidin: Induction of apoptosis by a natural product.
Daniel, P.T. and Koert, U. and Schuppan, J.
Angewandte Chemie International Edition 45 : 872-893. 30 January 2006

Guardians of cell death: the Bcl-2 family proteins.
Daniel, P.T. and Schulze-Osthoff, K. and Belka, C. and Guener, D.
Essays in Biochemistry 39 : 73-88. 1 October 2003

Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T. and Kroidl, A. and Kopp, J. and Sturm, I. and Moldenhauer, G. and Doerken, B. and Pezzutto, A.
Blood 92 (12): 4750-4757. 15 December 1998

Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.
Daniel, P.T. and Kroidl, A. and Cayeux, S. and Bargou, R.C. and Blankenstein, T. and Doerken, B.
Journal of Immunology 159 (8): 3808-3815. 15 October 1997

Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference.
Denkert, C. and Fuerstenberg, A. and Daniel, P.T. and Koch, I. and Koebel, M. and Weichert, W. and Siegert, A. and Hauptmann, S.
Oncogene 22 (54): 8653-8661. 27 November 2003

CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants.
Eberle, J. and Fecker, L.F. and Hossini, A.M. and Wieder, T. and Daniel, P.T. and Orfanos, C.E. and Geilen, C.C.
Oncogene 22 (57): 9131-9141. 11 December 2003

Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak and augments drug response.
Einsele-Scholz, S. and Malmsheimer, S. and Bertram, K. and Stehle, D. and Johaenning, J. and Manz, M. and Daniel, P.T. and Gillissen, B.F. and Schulze-Osthoff, K. and Essmann, F.
Journal of Cell Science 129 (11): 2213-2223. 1 June 2016

Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis.
Essmann, F. and Pohlmann, S. and Gillissen, B. and Daniel, P.T. and Schulze-Osthoff, K. and Jaenicke, R.U.
Journal of Biological Chemistry 280 (44): 37169-37177. 4 November 2005

Loss of proapoptotic Bcl-2-related multidomain proteins in primary melanomas is associated with poor prognosis.
Fecker, L.F. and Geilen, C.C. and Tchernev, G. and Trefzer, U. and Assaf, C. and Kurbanov, B.M. and Schwarz, C. and Daniel, P.T. and Eberle, J.
Journal of Investigative Dermatology 126 : 1366-1371. June 2006

Cellular fingerprints: a novel approach using large-scale cancer cell line data for the identification of potential anticancer agents.
Fuellbeck, M. and Dunkel, M. and Hossbach, J. and Daniel, P.T. and Preissner, R.
Chemical Biology & Drug Design 74 (5): 439-448. November 2009

Computer-assisted identification of small-molecule Bcl-2 modulators.
Fuellbeck, M. and Gebhardt, N. and Hossbach, J. and Daniel, P.T. and Preissner, R.
Computational Biology and Chemistry 33 (6): 451-456. December 2009

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
Gillissen, B. and Essmann, F. and Graupner, V. and Staerck, L. and Radetzki, S. and Doerken, B. and Schulze-Osthoff, K. and Daniel, P.T.
EMBO Journal 22 (14): 3580-3590. 15 July 2003

Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
Gillissen, B. and Essmann, F. and Hemmati, P.G. and Richter, A. and Richter, A. and Oztop, I. and Chinnadurai, G. and Doerken, B. and Daniel, P.T.
Journal of Cell Biology 179 (4): 701-715. 19 November 2007

Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode.
Gillissen, B. and Richter, A. and Richter, A. and Overkamp, T. and Essmann, F. and Hemmati, P.G. and Preissner, R. and Belka, C. and Daniel, P.T.
Cell Death & Disease 4 : e643. 23 May 2013

Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B. and Richter, A. and Richter, A. and Preissner, R. and Schulze-Osthoff, K. and Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292 (16): 6478-6492. 21 April 2017

Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.
Gillissen, B. and Wendt, J. and Richter, A. and Richter, A. and Mueer, A. and Overkamp, T. and Gebhardt, N. and Preissner, R. and Belka, C. and Doerken, B. and Daniel, P.T.
Journal of Cell Biology 188 (6): 851-862. 22 March 2010

2D and 3D similarity landscape analysis identifies PARP as a novel off-target for the drug Vatalanib.
Gohlke, B.O. and Overkamp, T. and Richter, A. and Richter, A. and Daniel, P.T. and Gillissen, B. and Preissner, R.
BMC Bioinformatics 16 (1): 308. 24 September 2015

Analysis of neuroendocrine differentiation and the p53/BAX pathway in UICC stage III colorectal carcinoma identifies patients with good prognosis.
Grabowski, P. and Sturm, I. and Schelwies, K. and Maaser, K. and Buhr, H.J. and Doerken, B. and Zeitz, M. and Daniel, P.T. and Scheruebl, H.
International Journal of Colorectal Disease 21 : 221-230. April 2006

Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level.
Graupner, V. and Alexander, E. and Overkamp, T. and Rothfuss, O. and De Laurenzi, V. and Gillissen, B.F. and Daniel, P.T. and Schulze-Osthoff, K. and Essmann, F.
Cell Death and Differentiation 18 (7): 1130-1139. July 2011

Disruption of cell death signaling in cancer: impact on disease prognosis and response to therapy.
Guener, D. and Belka, C. and Daniel, P.T.
Current Medicinal Chemistry Anti-Cancer Agents 3 (5): 319-326. 1 September 2003

Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.
Guener, D. and Sturm, I. and Hemmati, P. and Hermann, S. and Hauptmann, S. and Wurm, R. and Budach, V. and Doerken, B. and Lorenz, M. and Daniel, P.T.
International Journal of Cancer 103 (4): 445-454. 10 February 2003

Deregulation von Zellzyklus und Apoptose beim Plattenepithelkarzinom des Oesophagus.
Guener, D.
UNSPECIFIED thesis, UNSPECIFIED. 30 September 2003

Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway.
Habermehl, D. and Kammerer, B. and Handrick, R. and Eldh, T. and Gruber, C. and Cordes, N. and Daniel, P.T. and Plasswilm, L. and Bamberg, M. and Belka, C. and Jendrossek, V.
BMC Cancer 6 : 14. 17 January 2006

Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax.
Handrick, R. and Ganswindt, U. and Faltin, H. and Goecke, B. and Daniel, P.T. and Budach, W. and Belka, C. and Jendrossek, V.
Radiotherapy and Oncology 90 (3): 413-421. March 2009

Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-xL in a strictly caspase-3-dependent manner in human carcinoma cells.
Hasenjaeger, A. and Gillissen, B. and Mueller, A. and Normand, G. and Hemmati, P.G. and Schuler, M. and Doerken, B. and Daniel, P.T.
Oncogene 23 (26): 4523-4535. 3 June 2004

Bak functionally complements for loss of Bax during p14(ARF)-induced mitochondrial apoptosis in human cancer cells.
Hemmati, P.G. and Guener, D. and Gillissen, B. and Wendt, J. and von Haefen, C. and Chinnadurai, G. and Doerken, B. and Daniel, P.T.
Oncogene 25 (50): 6582-6594. 26 October 2006

Systematic genetic dissection of p14(ARF)-mediated mitochondrial cell death signaling reveals a key role for p21(CDKN1) and the BH3-only protein Puma/bbc3.
Hemmati, P.G. and Mueer, A. and Gillissen, B. and Overkamp, T. and Milojkovic, A. and Wendt, J. and Doerken, B. and Daniel, P.T.
Journal of Molecular Medicine 88 (6): 609-622. June 2010

Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.
Hemmati, P.G. and Normand, G. and Gillissen, B. and Wendt, J. and Doerken, B. and Daniel, P.T.
Oncogene 27 (53): 6707-6719. 4 December 2008

Loss of p21 disrupts p14ARF-induced G1 cell cycle arrest but augments p14ARF-induced apoptosis in human carcinoma cells.
Hemmati, P.G. and Normand, G. and Verdoodt, B. and von Haefen, C. and Hasenjaeger, A. and Guener, D. and Wendt, J. and Doerken, B. and Daniel, P.T.
Oncogene 24 (25): 4114-4128. 1 January 2005

Adenovirus-mediated overexpression of p14ARF induces p53 and Bax-independent apoptosis.
Hemmati, P.G. and Gillissen, B. and von Haefen, C. and Wendt, J. and Staerck, L. and Guener, D. and Doerken, B. and Daniel, P.T.
Oncogene 21 (20): 3149-3161. 9 May 2002

Assessment of free light chains in the cerebrospinal fluid of patients with lymphomatous meningitis - a pilot study.
Hildebrandt, B. and Mueller, C. and Pezzutto, A. and Daniel, P.T. and Doerken, B. and Scholz, C.
BMC Cancer 7 : 185. 3 October 2007

Inhibiting the inhibitors: retro-inverso Smac peptides.
Hossbach, J. and Michalsky, E. and Henklein, P. and Jaeger, M. and Daniel, P.T. and Preissner, R.
Peptides 30 (12): 2374-2379. December 2009

A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain.
Hossini, A.M. and Geilen, C.C. and Fecker, L.F. and Daniel, P.T. and Eberle, J.
Oncogene 25 : 2160-2169. 6 April 2006

Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway.
Hu, H. and Jiang, C. and Schuster, T. and Li, G.X. and Daniel, P.T. and Lue, J.
Molecular Cancer Therapeutics 5 : 1873-1882. July 2006

Inhibition of the ER Ca2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis.
Janssen, K. and Horn, S. and Niemann, M.T. and Daniel, P.T. and Schulze-Osthoff, K. and Fischer, U.
Journal of Cell Science 122 (Pt 24): 4481-4491. 15 December 2009

Long-term follow-up of patients with Philadelphia chromosome-positive chronic myeloid leukemia after stem cell mobilization under imatinib.
Kim, T.D. and Schwarz, M. and Kreuzer, K.A. and Kaeda, J. and Movassaghi, K. and Grille, P. and Daniel, P.T. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 52 (3): 517-520. March 2011

Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D. and Tuerkmen, S. and Schwarz, M. and Koca, G. and Nogai, H. and Bommer, C. and Doerken, B. and Daniel, P. and le Coutre, P.
Haematologica 95 (4): 582-588. April 2010

Adenine deoxynucleotides fludarabine and cladribine induce apoptosis in a CD95/Fas receptor, FADD and caspase-8-independent manner by activation of the mitochondrial cell death pathway.
Kloepfer, A. and Hasenjaeger, A. and Belka, C. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 23 : 9408-9418. 1 January 2004

Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule.
Lagresle, C. and Bella, C. and Daniel, P.T. and Krammer, P.H. and Defrance, T.
Journal of Immunology 154 (11): 5746-5756. 1 June 1995

Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
Li, M. and Jung, A. and Ganswindt, U. and Marini, P. and Friedl, A. and Daniel, P.T. and Lauber, K. and Jendrossek, V. and Belka, C.
Biochemical Pharmacology 79 (2): 122-129. 15 January 2010

Involvement of NAK-1, the human nur77 homologue, in surface IgM-mediated apoptosis in Burkitt lymphoma cell line BL41.
Mapara, M.Y. and Weinmann, P. and Bommert, K. and Daniel, P.T. and Bargou, R.C. and Doerken, B.
European Journal of Immunology 25 (9): 2506-2510. September 1995

Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo.
Marini, P. and Denzinger, S. and Schiller, D. and Kauder, S. and Welz, S. and Humphreys, R. and Daniel, P.T. and Jendrossek, V. and Budach, W. and Belka, C.
Oncogene 25 : 5145-5154. 24 August 2006

Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis.
Marini, P. and Schmid, A. and Jendrossek, V. and Faltin, H. and Daniel, P.T. and Budach, W. and Belka, C.
BMC Cancer 5 : 5. 14 January 2005

p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.
Milojkovic, A. and Hemmati, P.G. and Mueer, A. and Overkamp, T. and Chumduri, C. and Jaenicke, R.U. and Gillissen, B. and Daniel, P.T.
International Journal of Cancer 133 (11): 2551-2562. 1 December 2013

Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability.
Mrozek, A. and Petrowsky, H. and Sturm, I. and Kraus, J. and Hermann, S. and Hauptmann, S. and Lorenz, M. and Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 10 (4): 461-467. 1 April 2003

Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma.
Mueller, A. and Zang, C. and Chumduri, C. and Doerken, B. and Daniel, P.T. and Scholz, C.W.
International Journal of Cancer 133 (8): 1813-1824. 15 October 2013

p14ARF-induced apoptosis in p53-deficient cells is mediated by the BH3-only protein independent de-repression of Bak through down-regulation of Mcl-1 and Bcl-xL.
Muer, A. and Overkamp, T. and Gillissen, B. and Richter, A. and Pretzsch, T. and Milojkovic, A. and Doerken, B. and Daniel, P.T. and Hemmati, P.
Journal of Biological Chemistry 287 (21): 17343-17352. 18 May 2012

Pan-class I  PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.
Müller, A. and Gillissen, B. and Richter, A. and Richter, A. and Chumduri, C. and Daniel, P.T. and Scholz, C.W.
Cell Death & Disease 9 (3): 384. 7 March 2018

Adenoviral natural born killer gene therapy for malignant glioma.
Naumann, U. and Schmidt, F. and Wick, W. and Frank, B. and Weit, S. and Gillissen, B. and Daniel, P. and Weller, M.
Human Gene Therapy 14 (13): 1235-1246. 1 September 2003

Efficacy of triple therapies including ionising radiation, agonistic TRAIL antibodies and cisplatin.
Niyazi, M. and Marini, P. and Daniel, P.T. and Humphreys, R. and Jendrossek, V. and Belka, C.
Oncology Reports 21 (6): 1455-1460. June 2009

Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Niyazi, M. and Marini, P. and Daniel, P.T. and Humphreys, R. and Jendrossek, V. and Belka, C.
Strahlentherapie und Onkologie 185 (1): 8-18. January 2009

p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity.
Normand, G. and Hemmati, P.G. and Verdoodt, B. and von Haefen, C. and Wendt, J. and Guener, D. and May, E. and Doerken, B. and Daniel, P.T.
Journal of Biological Chemistry 280 : 7118-7130. 1 January 2005

Sequencing of NUMB transcripts in chronic myeloid leukaemia detects two single nucleotide polymorphisms.
Oberender, C. and Kaeda, J. and Pawlaczyk-Peter, B. and Daniel, P. and Arnold, R. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 54 (2): 421-422. February 2013

Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk/Bik.
Oppermann, M. and Geilen, C.C. and Fecker, L.F. and Gillissen, B. and Daniel, P.T. and Eberle, J.
Oncogene 24 : 7369-7380. 4 July 2005

Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells.
Ploetz, M. and Gillissen, B. and Hossini, A.M. and Daniel, P.T. and Eberle, J.
Cell Death and Differentiation 19 (12): 1928-1938. December 2012

The BH3-only protein Bim(L) overrides Bcl-2-mediated apoptosis resistance in melanoma cells.
Ploetz, M. and Gillissen, B. and Quast, S.A. and Berger, A. and Daniel, P.T. and Eberle, J.
Cancer Letters 335 (1): 100-108. 10 July 2013

Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK).
Ploetz, M. and Hossini, A.M. and Gillissen, B. and Daniel, P.T. and Stockfleth, E. and Eberle, J.
PLoS ONE 7 (4): e34549. 10 April 2012

Induction of apoptosis by enediyne antibiotic calicheamicin gammaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner.
Prokop, A. and Wrasidlo, W. and Lode, H. and Herold, R. and Lang, F. and Henze, G. and Doerken, B. and Wieder, T. and Daniel, P.T.
Oncogene 22 (57): 9107-9120. 11 December 2003

The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines.
Radetzki, S. and Koehne, C.H. and von Haefen, C. and Gillissen, B. and Sturm, I. and Doerken, B. and Daniel, P.T.
Oncogene 21 (2): 227-238. 10 January 2002

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.
Radhakrishnan, H. and Ilm, K. and Walther, W. and Shirasawa, S. and Sasazuki, T. and Daniel, P.T. and Gillissen, B. and Stein, U.
Cancer Letters 403 : 231-245. 10 September 2017

Dynamic expression profile of p21 WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy.
Rau, B. and Sturm, I. and Lage, H. and Berger, S. and Schneider, U. and Haupfmann, S. and Wust, P. and Riess, H. and Schlag, P.M. and Doerken, B. and Daniel, P.T.
Journal of Clinical Oncology 21 (18): 3391-3401. 15 September 2003

Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker.
Reimer, T.A. and Anagnostopoulos, I. and Erdmann, B. and Lehmann, I. and Stein, H. and Daniel, P. and Doerken, B. and Rehm, A.
BMC Cancer 5 (1): 47. 1 January 2005

Type I and type II reactions in TRAIL-induced apoptosis - results from dose-response studies.
Rudner, J. and Jendrossek, V. and Lauber, K. and Daniel, P.T. and Wesselborg, S. and Belka, C.
Oncogene 24 : 130-140. 6 January 2005

Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors.
Schelwies, K. and Sturm, I. and Grabowski, P. and Scherubl, H. and Schindler, I. and Hermann, S. and Stein, H. and Buhr, H.J. and Riecken, E.O. and Zeitz, M. and Doerken, B. and Daniel, P.T.
International Journal of Cancer 99 (4): 589-596. 1 June 2002

Tumor necrosis factor α sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-κB.
Schmelz, K. and Wieder, T. and Tamm, I. and Mueller, A. and Essmann, F. and Geilen, C.C. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 23 (40): 6743-6759. 2 September 2004

Dysferlin-peptides reallocate mutated dysferlin thereby restoring function.
Schoewel, V. and Marg, A. and Kunz, S. and Overkamp, T. and Siegert Carrazedo, R. and Zacharias, U. and Daniel, P.T. and Spuler, S.
PLoS ONE 7 (11): e49603. 20 November 2012

Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway.
Scholz, C. and Richter, A. and Lehmann, M. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 24 (47): 7031-7042. 27 October 2005

Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.
Scholz, C. and Wieder, T. and Staerck, L. and Essmann, F. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 24 : 1904-1913. 1 January 2005

Necrotic death but not irradiation abolishes costimulation of T-cell effector functions and survival by CD80-expressing tumor cells.
Staerck, L. and Scholz, C. and Blankenstein, T. and Doerken, B. and Daniel, P.T.
International Journal of Cancer 116 (1): 78-86. 1 January 2005

Costimulation by CD137/4-1BB inhibits T cell apoptosis and induces Bcl-xL and c-FLIPshort via phosphatidylinositol 3-kinase and AKT/protein kinase B.
Staerck, L. and Scholz, C. and Doerken, B. and Daniel, P.T.
European Journal of Immunology 35 : 1257-1266. 1 January 2005

Non-genotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.
Stuehmer, T. and Chatterjee, M. and Hildebrandt, M. and Herrmann, P. and Gollasch, H. and Gerecke, C. and Theurich, S. and Cigliano, L. and Manz, R.A. and Daniel, P.T. and Bommert, K. and Vassilev, L.T. and Bargou, R.C.
Blood 106 : 3609-3617. 4 August 2005

Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy.
Sturm, I. and Bosanquet, A.G. and Hermann, S. and Guener, D. and Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 10 (4): 477-484. 1 April 2003

In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis.
Sturm, I. and Bosanquet, A.G. and Hummel, M. and Doerken, B. and Daniel, P.T.
BMC Cancer 5 : 105. 18 August 2005

Silencing of APAF-1 in B-CLL results in poor prognosis in the case of concomitant p53 mutation.
Sturm, I. and Bosanquet, A.G. and Radetzki, S. and Hummel, M. and Doerken, B. and Daniel, P.T.
International Journal of Cancer 118 : 2329-2336. 1 May 2006

Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy.
Sturm, I. and Rau, B. and Schlag, P.M. and Wust, P. and Hildebrandt, B. and Riess, H. and Hauptmann, S. and Doerken, B. and Daniel, P.T.
BMC Cancer 6 : 124. 10 May 2006

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Sturm, I. and Stephan, C. and Gillissen, B. and Siebert, R. and Janz, M. and Radetzki, S. and Jung, K. and Loening, S. and Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 13 : 619-627. April 2006

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes.
Volcic, M. and Karl, S. and Baumann, B. and Salles, D. and Daniel, P. and Fulda, S. and Wiesmueller, L.
Nucleic Acids Research 40 (1): 181-195. January 2012

Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells.
Wendt, J. and Radetzki, S. and von Haefen, C. and Hemmati, P.G. and Guener, D. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 25 : 972-980. 16 February 2006

TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway.
Wendt, J. and von Haefen, C. and Hemmati, P. and Belka, C. and Doerken, B. and Daniel, P.T.
Oncogene 24 (25): 4052-4064. 1 January 2005

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.
Zaltsman, Y. and Shachnai, L. and Yivgi-Ohana, N. and Schwarz, M. and Maryanovich, M. and Houtkooper, R.H. and Vaz, F.M. and De Leonardis, F. and Fiermonte, G. and Palmieri, F. and Gillissen, B. and Daniel, P.T. and Jimenez, E. and Walsh, S. and Koehler, C.M. and Roy, S.S. and Walter, L. and Hajnoczky, G. and Gross, A.
Nature Cell Biology 12 (6): 553-562. June 2010

Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.
Zantl, N. and Weirich, G. and Zall, H. and Seiffert, B.M. and Fischer, S.F. and Kirschnek, S. and Hartmann, C. and Fritsch, R.M. and Gillissen, B. and Daniel, P.T. and Haecker, G.
Oncogene 26 (49): 7038-7048. 25 October 2007

Delayed allogeneic skin graft rejection in CD26-deficient mice.
Zhao, X. and Zhang, K. and Daniel, P. and Wisbrun, N. and Fuchs, H. and Fan, H.
Cellular and Molecular Immunology 16 (6): 557-567. June 2019

BCR-ABL positive cells and chronic myeloid leukemia in immune suppressed organ transplant recipients.
le Coutre, P. and Reinke, P. and Neuhaus, R. and Trappe, R. and Ringel, F. and Lalancette, M. and Hemmati, P.G. and Doerken, B. and Daniel, P.T.
European Journal of Haematology 84 (1): 26-33. 1 January 2010

Post-transplantation chronic myeloid leukemia.
le Coutre, P. and Schwarz, M. and Daniel, P. and Doerken, B.
Clinical Advances in Hematology & Oncology 9 (8): 627-629. August 2011

Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway.
von Haefen, C. and Gillissen, B. and Hemmati, P.G. and Wendt, J. and Guener, D. and Mrozek, A. and Belka, C. and Doerken, B. and Daniel, P.T.
Oncogene 23 (50): 8320-8332. 27 September 2004

Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway.
von Haefen, C. and Wendt, J. and Semini, G. and Sifringer, M. and Belka, C. and Radetzki, S. and Reutter, W. and Daniel, P.T. and Danker, K.
Apoptosis 16 (6): 636-651. March 2011

Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.
von Haefen, C. and Wieder, T. and Essmann, F. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 22 (15): 2236-2247. 1 April 2003

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.
von Haefen, C. and Wieder, T. and Gillissen, B. and Staerck, L. and Graupner, V. and Doerken, B. and Daniel, P.T.
Oncogene 21 (25): 4009-4019. 6 June 2002

Daumke, Oliver

Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A. and Xavier, A. and Abu Lubad, M. and Sigulla, J. and Kessler, M. and Hurwitz, R. and Meyer, T.F.
EBioMedicine 23 : 100-110. September 2017

Membrane fission by dynamin: what we know and what we need to know.
Antonny, B. and Burd, C. and De Camilli, P. and Chen, E. and Daumke, O. and Faelber, K. and Ford, M. and Frolov, V.A. and Frost, A. and Hinshaw, J.E. and Kirchhausen, T. and Kozlov, M.M. and Lenz, M. and Low, H.H. and McMahon, H. and Merrifield, C. and Pollard, T.D. and Robinson, P.J. and Roux, A. and Schmid, S.
EMBO Journal 35 (21): 2270-2284. 2 November 2016

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A. and Roske, Y. and Barth, C. and Lleras Forero, L. and Bravo-Rodriguez, K. and Redel, Al. and Kostova, S. and McShane, E. and Opitz, R. and Faelber, K. and Rau, K. and Mielke, T. and Daumke, O. and Selbach, M. and Sanchez-Garcia, E. and Rocks, O. and Panáková, D. and Heinemann, U. and Wanker, E.E.
Nature Communications 7 : 13047. 20 October 2016

Dynamics of the ligand binding domain layer during AMPA receptor activation.
Baranovic, J. and Chebli, M. and Salazar, H. and Carbone, A.L. and Faelber, K. and Lau, A.Y. and Daumke, O. and Plested, A.J.R.
Biophysical Journal 110 (4): 896-911. 23 February 2016

A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand, J. and Smith, E.S.J. and Schwefel, D. and Lapatsina, L. and Poole, K. and Omerbasic, D. and Kozlenkov, A. and Behlke, J. and Lewin, G.R. and Daumke, O.
EMBO Journal 31 (17): 3635-3646. 29 August 2012

Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach.
Chakrabarti, P.P. and Daumke, O. and Suveyzdis, Y. and Koetting, C. and Gerwert, K. and Wittinghofer, A.
Journal of Molecular Biology 367 (4): 983-95. 6 April 2007

Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module.
Daumke, O. and Gao, S. and von der Malsburg, A. and Haller, O. and Kochs, G.
Small GTPases 1 (1): 62-64. July 2010

Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
Daumke, O. and Lundmark, R. and Vallis, Y. and Martens, S. and Butler, P.J.G. and McMahon, H.T.
Nature 449 (7164): 923-927. 3 October 2007

Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily.
Daumke, O. and Praefcke, G.J.
Biopolymers 105 (8): 580-593. August 2016

Structural insights into membrane fusion at the endoplasmic reticulum.
Daumke, O. and Praefcke, G.J.
Proceedings of the National Academy of Sciences of the United States of America 108 (6): 2175-2176. 8 February 2011

BAR domain scaffolds in dynamin-mediated membrane fission.
Daumke, O. and Roux, A. and Haucke, V.
Cell 156 (5): 882-892. 27 February 2014

Mitochondrial homeostasis: How do dimers of mitofusins mediate mitochondrial fusion?
Daumke, O. and Roux, A.
Current Biology 27 (9): R353-R356. 8 May 2017

Protein-mediated membrane remodeling.
Daumke, O. and Unger, V.M.
Journal of Structural Biology 196 (1): 1-2. October 2016

Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.
Dick, A. and Graf, L. and Olal, D. and von der Malsburg, A. and Gao, S. and Kochs, G. and Daumke, O.
Journal of Biological Chemistry 290 (20): 12779-12792. 15 May 2015

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. and Czajkowski, M.T. and Barth, C. and Müller, P.M. and McShane, E. and Grunwald, S. and Beaudette, P. and Mecklenburg, N. and Volkmer, R. and Zühlke, K. and Dittmar, G. and Selbach, M. and Hammes, A. and Daumke, O. and Klussmann, E. and Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Structural insights into dynamin-mediated membrane fission.
Faelber, K. and Held, M. and Gao, S. and Posor, Y. and Haucke, V. and Noe, F. and Daumke, O.
Structure 20 (10): 1621-1628. 10 October 2012

Crystal structure of nucleotide-free dynamin.
Faelber, K. and Posor, Y. and Gao, S. and Held, M. and Roske, Y. and Schulze, D. and Haucke, V. and Noe, F. and Daumke, O.
Nature 477 (7366): 556-560. 29 September 2011

Struktur und Funktion des mechanochemischen Motorproteins Dynamin.
Faelber, K. and Daumke, O.
BIOspektrum 24 (5): 481-483. September 2018

Oligomerization of dynamin superfamily proteins in health and disease.
Faelber, K. and Gao, S. and Held, M. and Posor, Y. and Haucke, V. and Noé, F. and Daumke, O.
Progress in Molecular Biology and Translational Science 117 : 411-443. 2013

Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer.
Francy, C.A. and Clinton, R.W. and Froehlich, C. and Murphy, C. and Mears, J.A.
Scientific Reports 7 (1): 10744. 6 September 2017

Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein.
Fröhlich, C. and Grabiger, S. and Schwefel, D. and Faelber, K. and Rosenbaum, E. and Mears, J. and Rocks, O. and Daumke, O.
EMBO Journal 32 (9): 1280-1292. 2 May 2013

Structure of myxovirus resistance protein A reveals intra- and intermolecular domain interactions required for the antiviral function.
Gao, S. and von der Malsburg, A. and Dick, A. and Faelber, K. and Schroeder, G.F. and Haller, O. and Kochs, G. and Daumke, O.
Immunity 35 (4): 514-525. 28 October 2011

Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao, S. and von der Malsburg, A. and Paeschke, S. and Behlke, J. and Haller, O. and Kochs, G. and Daumke, O.
Nature 465 (7297): 502-506. 27 May 2010

New role for the (pro)renin receptor in T cell development.
Geisberger, S. and Maschke, U. and Gebhardt, M. and Kleinewietfeld, M. and Manzel, A. and Linker, R.A. and Chidgey, A. and Dechend, R. and Nguyen, G. and Daumke, O. and Muller, D.N. and Wright, M.D. and Binger, K.J.
Blood 126 (4): 504-507. 23 July 2015

Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.
Graf, L. and Dick, A. and Sendker, F. and Barth, E. and Marz, M. and Daumke, O. and Kochs, G.
Journal of Biological Chemistry 293 (9): 3056-3072. 2 March 2018

AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Götz, F. and Roske, Y. and Schulz, M.S. and Autenrieth, K. and Bertinetti, D. and Faelber, K. and Zühlke, K. and Kreuchwig, A. and Kennedy, E. and Krause, G. and Daumke, O. and Herberg, F.W. and Heinemann, U. and Klussmann, E.
Biochemical Journal 473 (13): 1881-1894. 28 June 2016

Dynamin-like MxA GTPase: Structural insights into oligomerization and implications for antiviral activity.
Haller, O. and Gao, S. and von der Malsburg, A. and Daumke, O. and Kochs, G.
Journal of Biological Chemistry 285 (37): 28419-28424. 10 September 2010

Structure of a classical MHC class I molecule that binds "non-classical" ligands.
Hee, C.S. and Gao, S. and Loll, B. and Miller, M.M. and Uchanska-Ziegler, B. and Daumke, O. and Ziegler, A.
PLoS Biology 8 (12): e1000557. 7 December 2010

Expression, purification and preliminary X-ray crystallographic analysis of the chicken MHC class I molecule YF1*7.1.
Hee, C.S. and Gao, S. and Miller, M.M. and Goto, R.M. and Ziegler, A. and Daumke, O. and Uchanska-Ziegler, B.
Acta Crystallographica Section F 65 (Pt 4): 422-425. 1 April 2009

Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature.
Henne, W.M. and Kent, H.M. and Ford, M.G.J. and Hegde, B.G. and Daumke, O. and Butler, P.J.G. and Mittal, R. and Langen, R. and Evans, P.R. and McMahon, H.T.
Structure 15 (7): 839-52. July 2007

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
Hessenberger, M. and Zerbes, R.M. and Rampelt, H. and Kunz, S. and Xavier, A.H. and Purfürst, B. and Lilie, H. and Pfanner, N. and van der Laan, M. and Daumke, O.
Nature Communications 8 : 15258. 31 May 2017

Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Jerke, U. and Marino, S.F. and Daumke, O. and Kettritz, R.
Scientific Reports 7 : 43328. 27 February 2017

Stomatin-domain proteins.
Lapatsina, L. and Brand, J. and Poole, K. and Daumke, O. and Lewin, G.R.
European Journal of Cell Biology 91 (4): 240-245. April 2012

Studying ribosome dynamics with simplified models.
Levi, M. and Noel, J.K. and Whitford, P.C.
Methods 30 March 2019 (In Press)

Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose.
Licht, A. and Bulut, H. and Scheffel, F.M. and Daumke, O. and Wehmeier, U.F. and Saenger, W. and Schneider, E. and Vahedi-Faridi, A.
Journal of Molecular Biology 406 (1): 92-105. 11 February 2011

Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill.
Lin, X. and Noel, J.K. and Wang, Q. and Ma, J. and Onuchic, J.N.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): E7905-E7913. 21 August 2018

Lowered pH leads to fusion peptide release and a highly dynamic intermediate of influenza hemagglutinin.
Lin, X.C. and Noel, J.K. and Wang, Q.H. and Ma, J.P. and Onuchic, J.N.
Journal of Physical Chemistry B 120 (36): 9654-9660. 15 September 2016

Structural basis for membrane tethering by a bacterial dynamin-like pair.
Liu, J. and Noel, J.K. and Low, H.H.
Nature Communications 9 (1): 3345. 21 August 2018

Sarcolemmal repair is a slow process and includes EHD2.
Marg, A. and Schoewel, V. and Timmel, T. and Schulze, A. and Shah, C. and Daumke, O. and Spuler, S.
Traffic 13 (9): 1286-1294. September 2012

A complex water network contributes to high-affinity binding in an antibody-antigen interface.
Marino, S.F. and Olal, D. and Daumke, O.
Data in Brief 6 : 394-397. March 2016

Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Melo, A.A. and Hegde, B.G. and Shah, C. and Larsson, E. and Isas, J.M. and Kunz, S. and Lundmark, R. and Langen, R. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 114 (22): 5629-5634. 30 May 2017

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization.
Moren, B. and Shah, C. and Howes, M.T. and Schieber, N.L. and McMahon, H.T. and Parton, R.G. and Daumke, O. and Lundmark, R.
Molecular Biology of the Cell 23 (7): 1316-1329. 9 February 2012

SMOG 2: A versatile software package for generating structure-based models.
Noel, J.K. and Levi, M. and Raghunathan, M. and Lammert, H. and Hayes, R.L. and Onuchic, J.N. and Whitford, P.C.
PLoS Computational Biology 12 (3): e1004794. 10 March 2016

Sequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamics.
Noel, J.K. and Morcos, F. and Onuchic, J.N.
F1000 Research 5 (F1000 Faculty Rev): 106. 26 January 2016

How EF-Tu can contribute to efficient proofreading of aa-tRNA by the ribosome.
Noel, J.K. and Whitford, P.C.
Nature Communications 7 : 13314. 31 October 2016

Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Oden, F. and Marino, S.F. and Brand, J. and Scheu, S. and Kriegel, C. and Olal, D. and Takvorian, A. and Westermann, J. and Yilmaz, B. and Hinz, M. and Daumke, O. and Höpken, U.E. and Müller, G. and Lipp, M.
Molecular Oncology 9 (7): 1348-1358. August 2015

Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation.
Olal, D. and Daumke, O.
Cell Reports 14 (9): 2092-2099. 8 March 2016

Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein.
Olal, D. and Dick, A. and Woods, V.L. and Liu, T. and Li, S. and Devignot, S. and Weber, F. and Saphire, E.O. and Daumke, O.
Nucleic Acids Research 42 (9): 6025-6037. 14 May 2014

Quantitative GTPase affinity purification identifies Rho family protein interaction partners.
Paul, F. and Zauber, H. and von Berg, L. and Rocks, O. and Daumke, O. and Selbach, M.
Molecular & Cellular Proteomics 16 (1): 73-85. 1 January 2017

Crystal structure of the dynamin tetramer.
Reubold, T.F. and Faelber, K. and Plattner, N. and Posor, Y. and Ketel, K. and Curth, U. and Schlegel, J. and Anand, R. and Manstein, D.J. and Noé, F. and Haucke, V. and Daumke, O. and Eschenburg, S.
Nature 525 (7569): 404-408. 17 September 2015

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
Schrade, K. and Tröger, J. and Eldahshan, A. and Zühlke, K. and Abdul Azeez, K.R. and Elkins, J.M. and Neuenschwander, M. and Oder, A. and Elkewedi, M.M.H. and Jaksch, S. and Andrae, K. and Li, J. and Fernandes, J. and Müller, P.M. and Grunwald, S. and Marino, S.F. and Vukićević, T. and Eichhorst, J. and Wiesner, B. and Weber, M. and Kapiloff, M. and Rocks, O. and Daumke, O. and Wieland, T. and Knapp, S. and von Kries, J.P. and Klussmann, E.
PLoS ONE 13 (1): e0191423. 26 January 2018

Roquin binding to target mRNAs involves a winged helix-turn-helix motif.
Schuetz, A. and Murakawa, Y. and Rosenbaum, E. and Landthaler, M. and Heinemann, U.
Nature Communications 5 : 5701. 11 December 2014

The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion.
Schulte, K. and Pawlowski, N. and Faelber, K. and Fröhlich, C. and Howard, J. and Daumke, O.
BMC Biology 14 (1): 14. 2 March 2016

Structural basis for aryl hydrocarbon receptor-mediated gene activation.
Schulte, K.W. and Green, E. and Wilz, A. and Platten, M. and Daumke, O.
Structure 25 (7): 1025-1033. 5 July 2017

GTP-dependent scaffold formation in the GTPase of Immunity Associated Protein family.
Schwefel, D. and Daumke, O.
Small GTPases 2 (1): 27-30. January 2011

Purification, crystallization and preliminary X-ray analysis of human GIMAP2.
Schwefel, D. and Froehlich, C. and Daumke, O.
Acta Crystallographica Section F 66 (6): 725-729. 1 June 2010

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Schwefel, D. and Froehlich, C. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Aravind, L. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 107 (47): 20299-20304. 23 November 2010

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel, D. and Arasu, B.S. and Marino, S.F. and Lamprecht, B. and Köchert, K. and Rosenbaum, E. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Rocks, O. and Mathas, S. and Daumke, O.
Structure 21 (4): 550-559. 2 April 2013

Host cell interactome of tyrosine-phosphorylated bacterial proteins.
Selbach, M. and Paul, F.E. and Brandt, S. and Guye, P. and Daumke, O. and Backert, S. and Dehio, C. and Mann, M.
Cell Host & Microbe 5 (4): 397-403. 23 April 2009

Phosphorylation of PACSIN2 by protein kinase C triggers the removal of caveolae from the plasma membrane.
Senju, Y. and Rosenbaum, E. and Shah, C. and Hamada-Nakahara, S. and Itoh, Y. and Yamamoto, K. and Hanawa-Suetsugu, K. and Daumke, O. and Suetsugu, S.
Journal of Cell Science 128 (15): 2766-2780. 1 August 2015

Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C. and Hegde, B.G. and Morén, B. and Behrmann, E. and Mielke, T. and Moenke, G. and Spahn, C.M. and Lundmark, R. and Daumke, O. and Langen, R.
Structure 22 (3): 409-420. 4 March 2014

A SEPT1-based scaffold is required for Golgi integrity and function.
Song, K. and Gras, C. and Capin, G. and Gimber, N. and Lehmann, M. and Mohd, S. and Puchkov, D. and Rödiger, M. and Wilhelmi, I. and Daumke, O. and Schmoranzer, J. and Schürmann, A. and Krauss, M.
Journal of Cell Science 132 (3): jcs225557. 1 February 2019

Molecular simulations suggest a force-dependent mechanism of vinculin activation.
Sun, L. and Noel, J.K. and Levine, H. and Onuchic, J.N.
Biophysical Journal 113 (8): 1697-1710. 17 October 2017

How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates.
Turco, E. and Witt, M. and Abert, C. and Bock-Bierbaum, T. and Su, M.Y. and Trapannone, R. and Sztacho, M. and Danieli, A. and Shi, X. and Zaffagnini, G. and Gamper, A. and Schuschnig, M. and Fracchiolla, D. and Bernklau, D. and Romanov, J. and Hartl, M. and Hurley, J.H. and Daumke, O. and Martens, S.
Autophagy 8 May 2019 (In Press)

FIP200 claw domain binding to p62 promotes autophagosome formation at ubiquitin condensates.
Turco, E. and Witt, M. and Abert, C. and Bock-Bierbaum, T. and Su, M.Y. and Trapannone, R. and Sztacho, M. and Danieli, A. and Shi, X. and Zaffagnini, G. and Gamper, A. and Schuschnig, M. and Fracchiolla, D. and Bernklau, D. and Romanov, J. and Hartl, M. and Hurley, J.H. and Daumke, O. and Martens, S.
Molecular Cell 74 (2): 330-346. 18 April 2019

Functional mapping of human dynamin-1-like GTPase domain based on X-ray structure analyses.
Wenger, J. and Klinglmayr, E. and Fröhlich, C. and Eibl, C. and Gimeno, A. and Hessenberger, M. and Puehringer, S. and Daumke, O. and Goettig, P.
PLoS ONE 8 (8): e71835. 19 August 2013

Anisotropic fluctuations in the ribosome determine tRNA kinetics.
Yang, H. and Noel, J.K. and Whitford, P.C.
Journal of Physical Chemistry B 121 (47): 10593-10601. 30 November 2017

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L. and Kärgel, E. and Franke, V. and McShane, E. and Schulz-Beiss, K.W. and Patone, G. and Schleussner, N. and Kolesnichenko, M. and Hübner, N. and Daumke, O. and Selbach, M. and Akalin, A. and Mathas, S. and Scheidereit, C.
Blood 133 (13): 1489-1494. 28 March 2019

De la Rosa, Kathrin

B-cell biology and development.
Pieper, K. and Grimbacher, B. and Eibel, H.
Journal of Allergy and Clinical Immunology 131 (4): 959-971. April 2013

A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.
Pieper, K. and Rizzi, M. and Speletas, M. and Smulski, C.R. and Sic, H. and Kraus, H. and Salzer, U. and Fiala, G.J. and Schamel, W.W. and Lougaris, V. and Plebani, A. and Hammarstrom, L. and Recher, M. and Germenis, A.E. and Grimbacher, B. and Warnatz, K. and Rolink, A.G. and Schneider, P. and Notarangelo, L.D. and Eibel, H.
Journal of Allergy and Clinical Immunology 133 (4): 1222-1225. April 2014

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Pieper, K. and Tan, J. and Piccoli, L. and Foglierini, M. and Barbieri, S. and Chen, Y. and Silacci-Fregni, C. and Wolf, T. and Jarrossay, D. and Anderle, M. and Abdi, A. and Ndungu, F.M. and Doumbo, O.K. and Traore, B. and Tran, T.M. and Jongo, S. and Zenklusen, I. and Crompton, P.D. and Daubenberger, C. and Bull, P.C. and Sallusto, F. and Lanzavecchia, A.
Nature 548 (7669): 597-601. 31 August 2017

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
Tan, J. and Pieper, K. and Piccoli, L. and Abdi, A. and Foglierini, M. and Geiger, R. and Tully, C.M. and Jarrossay, D. and Ndungu, F.M. and Wambua, J. and Bejon, P. and Silacci Fregni, C. and Fernandez-Rodriguez, B. and Barbieri, S. and Bianchi, S. and Marsh, K. and Thathy, V. and Corti, D. and Sallusto, F. and Bull, P. and Lanzavecchia, A.
Nature 529 (7584): 105-109. 7 January 2016

Deubzer, Hedwig (ECRC)

Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.
Arnhold, V. and Schmelz, K. and Proba, J. and Winkler, A. and Wünschel, J. and Toedling, J. and Deubzer, H.E. and Künkele, A. and Eggert, A. and Schulte, J.H. and Hundsdoerfer, P.
Oncotarget 9 (2): 2304-2319. 2018

Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition.
Blattmann, C. and Oertel, S. and Ehemann, V. and Thiemann, M. and Huber, P.E. and Bischof, M. and Witt, O. and Deubzer, H.E. and Kulozik, A.E. and Debus, J. and Weber, K.J.
International Journal of Radiation Oncology, Biology, Physics 78 (1): 237-245. 1 September 2010

Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.
Brockmann, M. and Poon, E. and Berry, T. and Carstensen, A. and Deubzer, H.E. and Rycak, L. and Jamin, Y. and Thway, K. and Robinson, S.P. and Roels, F. and Witt, O. and Fischer, M. and Chesler, L. and Eilers, M.
Cancer Cell 24 (1): 75-89. 8 July 2013

Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells.
Deubzer, H. and Busche, B. and Rönndahl, G. and Eikel, D. and Michaelis, M. and Cinatl, J. and Schulze, S. and Nau, H. and Witt, O.
Leukemia Research 30 (9): 1167-1175. September 2006

Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro.
Deubzer, H.E. and Ehemann, V. and Kulozik, A.E. and Westermann, F. and Savelyeva, L. and Kopp-Schneider, A. and Riester, D. and Schwab, M. and Witt, O.
Cancer Letters 264 (1): 21-28. 8 June 2008

Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.
Deubzer, H.E. and Ehemann, V. and Westermann, F. and Heinrich, R. and Mechtersheimer, G. and Kulozik, A.E. and Schwab, M. and Witt, O.
International Journal of Cancer 122 (8): 1891-900. 15 April 2008

Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae.
Deubzer, H.E. and Obaro, S.K. and Newman, V.O. and Adegbola, R.A. and Greenwood, B.M. and Henderson, D.C.
Journal of Infectious Diseases 190 (10): 1758-1761. 15 November 2004

HDAC11 is a novel drug target in carcinomas.
Deubzer, H.E. and Schier, M.C. and Oehme, I. and Lodrini, M. and Haendler, B. and Sommer, A. and Witt, O.
International Journal of Cancer 132 (9): 2200-2208. 1 May 2013

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Ecker, J. and Oehme, I. and Mazitschek, R. and Korshunov, A. and Kool, M. and Hielscher, T. and Kiss, J. and Selt, F. and Konrad, C. and Lodrini, M. and Deubzer, H.E. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Witt, O. and Milde, T.
Acta Neuropathologica Communications 3 : 22. 3 April 2015

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.
Fabian, J. and Lodrini, M. and Oehme, I. and Schier, M.C. and Thole, T.M. and Hielscher, T. and Kopp-Schneider, A. and Opitz, L. and Capper, D. and von Deimling, A. and Wiegand, I. and Milde, T. and Mahlknecht, U. and Westermann, F. and Popanda, O. and Roels, F. and Hero, B. and Berthold, F. and Fischer, M. and Kulozik, A.E. and Witt, O. and Deubzer, H.E.
Cancer Research 74 (9): 2604-2616. 1 May 2014

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Fabian, J. and Opitz, D. and Althoff, K. and Lodrini, M. and Hero, B. and Volland, R. and Beckers, A. and de Preter, K. and Decock, A. and Patil, N. and Abba, M. and Kopp-Schneider, A. and Astrahantseff, K. and Wünschel, J. and Pfeil, S. and Ercu, M. and Künkele, A. and Hu, J. and Thole, T. and Schweizer, L. and Mechtersheimer, G. and Carter, D. and Cheung, B.B. and Popanda, O. and von Deimling, A. and Koster, J. and Versteeg, R. and Schwab, M. and Marshall, G.M. and Speleman, F. and Erb, U. and Zoeller, M. and Allgayer, H. and Simon, T. and Fischer, M. and Kulozik, A.E. and Eggert, A. and Witt, O. and Schulte, J.H. and Deubzer, H.E.
Oncotarget 7 (41): 66344-66359. 11 October 2016

RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.
Gottlieb, A. and Althoff, K. and Grunewald, L. and Thor, T. and Odersky, A. and Schulte, M. and Deubzer, H.E. and Heukamp, L. and Eggert, A. and Schramm, A. and Schulte, J.H. and Künkele, A.
Oncotarget 8 (17): 27882-27891. 25 April 2017

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
Han, Y. and Lindner, S. and Bei, Y. and Dorado Garcia, H. and Timme, N. and Althoff, K. and Odersky, A. and Schramm, A. and Lissat, A. and Künkele, A. and Deubzer, H.E. and Eggert, A. and Schulte, J.H. and Henssen, A.G.
Cancer Letters 445 : 24-33. 31 March 2019

CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programs in neuroblastoma cells.
Henrich, K.O. and Bauer, T. and Schulte, J. and Ehemann, V. and Deubzer, H. and Gogolin, S. and Muth, D. and Fischer, M. and Benner, A. and König, R. and Schwab, M. and Westermann, F.
Cancer Research 71 (8): 3142-3151. 15 April 2011

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma.
Kocak, H. and Ackermann, S. and Hero, B. and Kahlert, Y. and Oberthuer, A. and Juraeva, D. and Roels, F. and Theissen, J. and Westermann, F. and Deubzer, H. and Ehemann, V. and Brors, B. and Odenthal, M. and Berthold, F. and Fischer, M.
Cell Death & Disease 4 : e586. 11 April 2013

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.
Künkele, A. and De Preter, K. and Heukamp, L. and Thor, T. and Pajtler, K.W. and Hartmann, W. and Mittelbronn, M. and Grotzer, M.A. and Deubzer, H.E. and Speleman, F. and Schramm, A. and Eggert, A. and Schulte, J.H.
Neuro-Oncology 14 (7): 859-869. 1 July 2012

Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells.
Lacroix, J. and Leuchs, B. and Li, J. and Hristov, G. and Deubzer, H.E. and Kulozik, A.E. and Rommelaere, J. and Schlehofer, J.R. and Witt, O.
International Journal of Cancer 127 (5): 1230-1239. 1 September 2010

Neuroblastoma imaging.
Ley, S. and Ley-Zaporozhan, J. and Günther, P. and Deubzer, H.E. and Witt, O. and Schenk, J.P.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 183 (3): 217-225. March 2011

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
Lodrini, M. and Oehme, I. and Schroeder, C. and Milde, T. and Schier, M.C. and Kopp-Schneider, A. and Schulte, J.H. and Fischer, M. and De Preter, K. and Pattyn, F. and Castoldi, M. and Muckenthaler, M.U. and Kulozik, A.E. and Westermann, F. and Witt, O. and Deubzer, H.E.
Nucleic Acids Research 41 (12): 6018-6033. 1 July 2013

Minichromosome maintenance complex is a critical node in the miR-183 signaling network of MYCN-amplified neuroblastoma cells.
Lodrini, M. and Poschmann, G. and Schmidt, V. and Wünschel, J. and Dreidax, D. and Witt, O. and Höfer, T. and Meyer, H.E. and Stühler, K. and Eggert, A. and Deubzer, H.E.
Journal of Proteome Research 15 (7): 2178-2186. 1 July 2016

Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma.
Lodrini, M. and Sprüssel, A. and Astrahantseff, K. and Tiburtius, D. and Konschak, R. and Lode, H.N. and Fischer, M. and Keilholz, U. and Eggert, A. and Deubzer, H.E.
Oncotarget 8 (49): 85234-85251. 17 October 2017

Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins.
Michaelis, M. and Bliss, J. and Arnold, S.C. and Hinsch, N. and Rothweiler, F. and Deubzer, H.E. and Witt, O. and Langer, K. and Doerr, H.W. and Wels, W.S. and Cinatl, J.
Clinical Cancer Research 14 (20): 6531-6537. 16 October 2008

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.
Michaelis, M. and Kleinschmidt, M.C. and Barth, S. and Rothweiler, F. and Geiler, J. and Breitling, R. and Mayer, B. and Deubzer, H. and Witt, O. and Kreuter, J. and Doerr, H.W. and Cinatl, J. and Cinatl, J.
Biochemical Pharmacology 79 (2): 130-136. 15 January 2010

Nestin expression identifies ependymoma patients with poor outcome.
Milde, T. and Hielscher, T. and Witt, H. and Kool, M. and Mack, S.C. and Deubzer, H.E. and Oehme, I. and Lodrini, M. and Benner, A. and Taylor, M.D. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Witt, O. and Korshunov, A.
Brain Pathology 22 (6): 848-860. November 2012

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
Milde, T. and Kleber, S. and Korshunov, A. and Witt, H. and Hielscher, T. and Koch, P. and Kopp, H.G. and Jugold, M. and Deubzer, H.E. and Oehme, I. and Lodrini, M. and Gröne, H.J. and Benner, A. and Brüstle, O. and Gilbertson, R.J. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Martin-Villalba, A. and Witt, O.
Acta Neuropathologica 122 (5): 637-650. November 2011

HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.
Milde, T. and Lodrini, M. and Savelyeva, L. and Korshunov, A. and Kool, M. and Brueckner, L.M. and Antunes, A.S.L.M. and Oehme, I. and Pekrun, A. and Pfister, S.M. and Kulozik, A.E. and Witt, O. and Deubzer, H.E.
Journal of Neuro-Oncology 110 (3): 335-348. December 2012

HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth.
Milde, T. and Oehme, I. and Korshunov, A. and Kopp-Schneider, A. and Remke, M. and Northcott, P. and Deubzer, H.E. and Lodrini, M. and Taylor, M.D. and von Deimling, A. and Pfister, S. and Witt, O.
Clinical Cancer Research 16 (12): 3240-3252. 15 June 2010

Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma.
Milde, T. and Pfister, S. and Korshunov, K. and Deubzer, H.E. and Oehme, I. and Ernst, A. and Starzinski-Powitz, A. and Seitz, A. and Lichter, P. and von Deimling, A. and Witt, O.
Genes Chromosomes & Cancer 48 (3): 229-238. March 2009

Serotype-specific pneumococcal antibodies in breast milk of Gambian women immunized with a pneumococcal polysaccharide vaccine during pregnancy.
Obaro, S.K. and Deubzer, H.E. and Newman, V.O. and Adegbola, R.A. and Greenwood, B.M. and Henderson, D.C.
Pediatric Infectious Disease Journal 23 (11): 1023-1029. November 2004

Targeting of HDAC8 and investigational inhibitors in neuroblastoma.
Oehme, I. and Deubzer, H.E. and Lodrini, M. and Milde, T. and Witt, O.
Expert Opinion on Investigational Drugs 18 (11): 1605-1617. November 2009

Histone deacetylase 8 in neuroblastoma tumorigenesis.
Oehme, I. and Deubzer, H.E. and Wegener, D. and Pickert, D. and Linke, J.P. and Hero, B. and Kopp-Schneider, A. and Westermann, F. and Ulrich, S.M. and von Deimling, A. and Fischer, M. and Witt, O.
Clinical Cancer Research 15 (1): 91-99. January 2009

Histone deacetylase 10 promotes autophagy-mediated cell survival.
Oehme, I. and Linke, J.P. and Böck, B.C. and Milde, T. and Lodrini, M. and Hartenstein, B. and Wiegand, I. and Eckert, C. and Roth, W. and Kool, M. and Kaden, S. and Gröne, H.J. and Schulte, J.H. and Lindner, S. and Hamacher-Brady, A. and Brady, N.R. and Deubzer, H.E. and Witt, O.
Proceedings of the National Academy of Sciences of the United States of America 110 (28): E2592-E2601. 9 July 2013

Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications.
Oevermann, L. and Zimmermann, C. and Voigt, S. and Künkele, A. and Lobitz, S. and Eggert, A. and Schulte, J.H. and Kaufer, B.B. and Deubzer, H.E.
Bone Marrow Transplantation 15 April 2019 (In Press)

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.
Pajtler, K.W. and Sadowski, N. and Ackermann, S. and Althoff, K. and Schönbeck, K. and Batzke, K. and Schäfers, S. and Odersky, A. and Heukamp, L. and Astrahantseff, K. and Künkele, A. and Deubzer, H.E. and Schramm, A. and Sprüssel, A. and Thor, T. and Lindner, S. and Eggert, A. and Fischer, M. and Schulte, J.H.
Oncotarget 8 (4): 6730-6741. 24 January 2017

Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation.
Rettig, I. and Koeneke, E. and Trippel, F. and Mueller, W.C. and Burhenne, J. and Kopp-Schneider, A. and Fabian, J. and Schober, A. and Fernekorn, U. and von Deimling, A. and Deubzer, H.E. and Milde, T. and Witt, O. and Oehme, I.
Cell Death & Disease 6 : e1657. 19 February 2015

Childhood cancer predisposition syndromes - a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.
Ripperger, T. and Bielack, S.S. and Borkhardt, A. and Brecht, I.B. and Burkhardt, B. and Calaminus, G. and Debatin, K.M. and Deubzer, H. and Dirksen, U. and Eckert, C. and Eggert, A. and Erlacher, M. and Fleischhack, G. and Frühwald, M.C. and Gnekow, A. and Goehring, G. and Graf, N. and Hanenberg, H. and Hauer, J. and Hero, B. and Hettmer, S. and von Hoff, K. and Horstmann, M. and Hoyer, J. and Illig, T. and Kaatsch, P. and Kappler, R. and Kerl, K. and Klingebiel, T. and Kontny, U. and Kordes, U. and Körholz, D. and Koscielniak, E. and Kramm, C.M. and Kuhlen, M. and Kulozik, A.E. and Lamottke, B. and Leuschner, I. and Lohmann, D.R. and Meinhardt, A. and Metzler, M. and Meyer, L.H. and Moser, O. and Nathrath, M. and Niemeyer, C.M. and Nustede, R. and Pajtler, K.W. and Paret, C. and Rasche, M. and Reinhardt, D. and Rieß, O. and Russo, A. and Rutkowski, S. and Schlegelberger, B. and Schneider, D. and Schneppenheim, R. and Schrappe, M. and Schroeder, C. and von Schweinitz, D. and Simon, T. and Sparber-Sauer, M. and Spix, C. and Stanulla, M. and Steinemann, D. and Strahm, B. and Temming, P. and Thomay, K. and von Bueren, A.O. and Vorwerk, P. and Witt, O. and Wlodarski, M. and Wössmann, W. and Zenker, M. and Zimmermann, S. and Pfister, S.M. and Kratz, C.P.
American Journal of Medical Genetics Part A 173 (4): 1017-1037. April 2017

Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells.
Schulte, J.H. and Kirfel, J. and Lim, S. and Schramm, A. and Friedrichs, N. and Deubzer, H.E. and Witt, O. and Eggert, A. and Buettner, R.
Cancer Letters 271 (1): 56-63. 18 November 2008

2017 GPOH guidelines for diagnosis and treatment of patients with neuroblastic tumors.
Simon, T. and Hero, B. and Schulte, J.H. and Deubzer, H. and Hundsdoerfer, P. and von Schweinitz, D. and Fuchs, J. and Schmidt, M. and Prasad, V. and Krug, B. and Timmermann, B. and Leuschner, I. and Fischer, M. and Langer, T. and Astrahantseff, K. and Berthold, F. and Lode, H. and Eggert, A.
Klinische Padiatrie 229 (3): 147-167. May 2017

HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells.
Wegener, D. and Deubzer, H.E. and Oehme, I. and Milde, T. and Hildmann, C. and Schwienhorst, A. and Witt, O.
Anti-Cancer Drugs 19 (9): 849-857. October 2008

Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay.
Wegener, D. and Hildmann, C. and Riester, D. and Schober, A. and Meyer-Almes, F.J. and Deubzer, H.E. and Oehme, I. and Witt, O. and Lang, S. and Jaensch, M. and Makarov, V. and Lange, C. and Busse, B. and Schwienhorst, A.
Biochemical Journal 413 (1): 143-150. 1 July 2008

Targeting histone deacetylases in neuroblastoma.
Witt, O. and Deubzer, H.E. and Lodrini, M. and Milde, T. and Oehme, I.
Current Pharmaceutical Design 15 (4): 436-447. 2009

HDAC family: What are the cancer relevant targets?
Witt, O. and Deubzer, H.E. and Milde, T. and Oehme, I.
Cancer Letters 277 (1): 8-21. 8 May 2009

Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma or leukemia.
Witt, O. and Milde, T. and Deubzer, H.E. and Oehme, I. and Witt, R. and Kulozik, A. and Eisenmenger, A. and Abel, U. and Karapanagiotou-Schenkel, I.
Klinische Padiatrie 224 (6): 398-403. October 2012

Di Virgilio, Michela

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K. and Kranz, A. and Fohgrub, J. and Jolly, A. and Bledau, A.S. and Di Virgilio, M. and Lesche, M. and Dahl, A. and Höfer, T. and Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018

A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y. and Malehmir, M. and Healy, M.E. and Bettermann, K. and Lorentzen, A. and Vucur, M. and Ahuja, A.K. and Böhm, F. and Mertens, J.C. and Shimizu, Y. and Frick, L. and Remouchamps, C. and Mutreja, K. and Kähne, T. and Sundaravinayagam, D. and Wolf, M.J. and Rehrauer, H. and Koppe, C. and Speicher, T. and Padrissa-Altés, S. and Maire, R. and Schattenberg, J.M. and Jeong, J.S. and Liu, Lei and Zwirner, S. and Boger, R. and Hüser, N. and Davis, R.J. and Müllhaupt, B. and Moch, H. and Schulze-Bergkamen, H. and Clavien, P.A. and Werner, S. and Borsig, L. and Luther, S.A. and Jost, P.J. and Weinlich, R. and Unger, K. and Behrens, A. and Hillert, L. and Dillon, C. and Di Virgilio, M. and Wallach, D. and Dejardin, E. and Zender, L. and Naumann, M. and Walczak, H. and Green, D.R. and Lopes, M. and Lavrik, I. and Luedde, T. and Heikenwalder, M. and Weber, A.
Cancer Cell 32 (3): 342-359. 11 September 2017

Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Bothmer, A. and Robbiani, D.F. and Di Virgilio, M. and Bunting, S.F. and Klein, I.A. and Feldhahn, N. and Barlow, J. and Chen, H.T. and Bosque, D. and Callen, E. and Nussenzweig, A. and Nussenzweig, M.C.
Molecular Cell 42 (3): 319-329. 6 May 2011

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Callen, E. and Di Virgilio, M. and Kruhlak, M.J. and Nieto-Soler, M. and Wong, N. and Chen, H.T. and Faryabi, R.B. and Polato, F. and Santos, M. and Starnes, L.M. and Wesemann, D.R. and Lee, J.E. and Tubbs, A. and Sleckman, B.P. and Daniel, J.A. and Ge, K. and Alt, F.W. and Fernandez-Capetillo, O. and Nussenzweig, M.C. and Nussenzweig, A.
Cell 153 (6): 1266-1280. 6 June 2013

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Callen, E. and Jankovic, M. and Wong, N. and Zha, S. and Chen, H.T. and Difilippantonio, S. and Di Virgilio, M. and Heidkamp, G. and Alt, F.W. and Nussenzweig, A. and Nussenzweig, M.
Molecular Cell 34 (3): 285-297. 15 May 2009

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V. and Rosen, D.B. and Wang, Q. and Gazumyan, A. and Pai, J.A. and Oliveira, T.Y. and Sundaravinayagam, D. and Zhang, W. and Andreani, M. and Keller, L. and Kieffer-Kwon, K.R. and Pękowska, A. and Jung, S. and Driesner, M. and Subbotin, R.I. and Casellas, R. and Chait, B.T. and Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72 (4): 636-649. 15 November 2018

Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Di Virgilio, M. and Callen, E. and Yamane, A. and Zhang, W. and Jankovic, M. and Gitlin, A.D. and Feldhahn, N. and Resch, W. and Oliveira, T.Y. and Chait, B.T. and Nussenzweig, A. and Casellas, R. and Robbiani, D.F. and Nussenzweig, M.C.
Science 339 (6120): 711-715. 8 February 2013

PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin.
Di Virgilio, M. and Ying, C.Y. and Gautier, J.
DNA Repair 8 (11): 1311-1320. 2 November 2009

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11.
Di Virgilio, M. and Gautier, J.
Journal of Cell Biology 171 (5): 765-771. 5 December 2005

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.
Dorsett, Y. and McBride, K.M. and Jankovic, M. and Gazumyan, A. and Thai, T.H. and Robbiani, D.F. and Di Virgilio, M. and Reina San-Martin, B. and Heidkamp, G. and Schwickert, T.A. and Eisenreich, T. and Rajewsky, K. and Nussenzweig, M.C.
Immunity 28 (5): 630-638. 16 May 2008

Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.
Gazumyan, A. and Timachova, K. and Yuen, G. and Siden, E. and Di Virgilio, M. and Woo, E.M. and Chait, B.T. and Reina San-Martin, B. and Nussenzweig, M.C. and McBride, K.M.
Molecular and Cellular Biology 31 (3): 442-429. February 2011

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.
Klein, I.A. and Resch, W. and Jankovic, M. and Oliveira, T. and Yamane, A. and Nakahashi, H. and Di Virgilio, M. and Bothmer, A. and Nussenzweig, A. and Robbiani, D.F. and Casellas, R. and Nussenzweig, M.C.
Cell 147 (1): 95-106. 30 September 2011

An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex.
Kracker, S. and Di Virgilio, M. and Schwartzentruber, J. and Cuenin, C. and Forveille, M. and Deau, M.C. and McBride, K.M. and Majewski, J. and Gazumyan, A. and Seneviratne, S. and Grimbacher, B. and Kutukculer, N. and Herceg, Z. and Cavazzana, M. and Jabado, N. and Nussenzweig, M.C. and Fischer, A. and Durandy, A.
Journal of Allergy and Clinical Immunology 135 (4): 998-1007. April 2015

Novel pathogenic mechanisms of congenital insensitivity to pain with anhidrosis genetic disorder unveiled by functional analysis of neurotrophic tyrosine receptor kinase type 1/nerve growth factor receptor mutations.
Miranda, C. and Di Virgilio, M. and Selleri, S. and Zanotti, G. and Pagliardini, S. and Pierotti, M.A. and Greco, A.
Journal of Biological Chemistry 277 (8): 6455-6462. 22 February 2002

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.
Pavri, R. and Gazumyan, A. and Jankovic, M. and Di Virgilio, M. and Klein, I. and Ansarah-Sobrinho, C. and Resch, W. and Yamane, A. and Reina San-Martin, B. and Barreto, V. and Nieland, T.J. and Root, D.E. and Casellas, R. and Nussenzweig, M.C.
Cell 143 (1): 122-133. 1 October 2010

MAD2L2 promotes open chromatin in embryonic stem cells and derepresses the Dppa3 locus.
Rahjouei, A. and Pirouz, M. and Di Virgilio, M. and Kamin, D. and Kessel, M.
Stem Cell Reports 8 (4): 813-821. 11 April 2017

PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones.
Sander, S. and Chu, V.T. and Yasuda, T. and Franklin, A. and Graf, R. and Calado, D.P. and Li, S. and Imami, K. and Selbach, M. and Di Virgilio, M. and Bullinger, L. and Rajewsky, K.
Immunity 43 (6): 1075-1086. 15 December 2015

DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Volk, T. and Pannicke, U. and Reisli, I. and Bulashevska, A. and Ritter, J. and Björkman, A. and Schäffer, A.A. and Fliegauf, M. and Sayar, E.H. and Salzer, U. and Fisch, P. and Pfeifer, D. and Di Virgilio, M. and Cao, H. and Yang, F. and Zimmermann, K. and Keles, S. and Caliskaner, Z. and Güner, S.Ü. and Schindler, D. and Hammarström, L. and Rizzi, M. and Hummel, M. and Pan-Hammarstroem, Q. and Schwarz, K. and Grimbacher, B.
Human Molecular Genetics 24 (25): 7361-7372. 20 December 2015

Diecke, Sebastian (MDC/BIH)

Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes.
Burridge, P.W. and Diecke, S. and Matsa, E. and Sharma, A. and Wu, H. and Wu, J.C.
Methods in Molecular Biology 1353 : 119-130. 2016

SURF1 mutations causative of Leigh syndrome impair human neurogenesis.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Juettner, R. and Zink, A. and Mlody, B. and Glazar, P. and Secker, C. and Ciptasari, U.H. and Stenzel, W. and Hahn, T. and Diecke, S. and Priller, J. and Gotthardt, M. and Kuehn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
bioRxiv : 551390. 20 February 2019

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. and Ofenbauer, A. and Bulut, S.I. and Uyar, B. and Baytek, G. and Sommermeier, A. and Seelk, S. and He, M. and Hirsekorn, A. and Vucicevic, D. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
Kolundzic, E. and Ofenbauer, A. and Uyar, B. and Sommermeier, A. and Seelk, S. and He, M. and Baytek, G. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
bioRxiv : 185116. 6 September 2017

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. and Kirchner, M. and Uyar, B. and Cheng, J.Y. and Russo, G. and Hernandez-Miranda, L.R. and Szymborska, A. and Zauber, H. and Rudolph, I.M. and Willnow, T.E. and Akalin, A. and Haucke, V. and Gerhardt, H. and Birchmeier, C. and Kühn, R. and Krauss, M. and Diecke, S. and Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

The translational landscape of the human heart.
van Heesch, S. and Witte, F. and Schneider-Lunitz, V. and Schulz, J.F. and Adami, E. and Faber, A.B. and Kirchner, M. and Maatz, H. and Blachut, S. and Sandmann, C.L. and Kanda, M. and Worth, C.L. and Schafer, S. and Calviello, L. and Merriott, R. and Patone, G. and Hummel, O. and Wyler, E. and Obermayer, B. and Mücke, M.B. and Lindberg, E.L. and Trnka, F. and Memczak, S. and Schilling, M. and Felkin, L.E. and Barton, P.J.R. and Quaife, N.M. and Vanezis, K. and Diecke, S. and Mukai, M. and Mah, N. and Oh, S.J. and Kurtz, A. and Schramm, C. and Schwinge, D. and Sebode, M. and Harakalova, M. and Asselbergs, F.W. and Vink, A. and de Weger, R.A. and Viswanathan, S. and Widjaja, A.A. and Gärtner-Rommel, A. and Milting, H. and Dos Remedios, C. and Knosalla, C. and Mertins, P. and Landthaler, M. and Vingron, M. and Linke, W.A. and Seidman, J.G. and Seidman, C.E. and Rajewsky, N. and Ohler, U. and Cook, S.A. and Hubner, N.
Cell 30 May 2019 (In Press)

Dietz, Rainer

B-Myb, a repressed trans-activating protein.
Ansieau, S. and Kowenz-Leutz, E. and Dechend, R. and Leutz, A.
Journal of Molecular Medicine 75 (11-12): 815-819. November 1997

Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A. and Zelarayan, L. and Betney, R. and Gehrke, C. and Dunger, S. and Noack, C. and Busjahn, A. and Huelsken, J. and Taketo, M.M. and Birchmeier, W. and Dietz, R. and Bergmann, M.W.
Circulation Research 100 (9): 1353-1362. 11 May 2007

Ventricular remodeling after acute myocardial infarction.
Dietz, R. and Osterziel, K.J. and Willenbrock, R. and Gulba, D.C. and von Harsdorf, R.
Thrombosis and Haemostasis 82 (Suppl 1): 73-75. September 1999

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B. and Heuser, A. and Wichter, T. and Paul, M. and Basson, C.T. and McDermott, D.A. and Lerman, B.B. and Markowitz, S.M. and Ellinor, P.T. and MacRae, C.A. and Peters, S. and Grossmann, K.S. and Drenckhahn, J. and Michely, B. and Sasse-Klaassen, S. and Birchmeier, W. and Dietz, R. and Breithardt, G. and Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36 (11): 1162-1164. November 2004

Subacute coronary stent thrombosis in cancer patients.
Gross, C.M. and Posch, M.G. and Geier, C. and Olthoff, H. and Kraemer, J. and Dechend, R. and Dietz, R. and Oezcelik, C.
Journal of the American College of Cardiology 51 (12): 1232-1233. 25 March 2008

Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Henke, N. and Schmidt-Ullrich, R. and Dechend, R. and Park, J.K. and Qadri, F. and Wellner, M. and Obst, M. and Gross, V. and Dietz, R. and Luft, F.C. and Scheidereit, C. and Mueller, D.N.
Circulation Research 101 (3): 268-276. 3 August 2007

Insulin-like growth factor-I and risk of breast cancer.
Strohm, O. and Osterziel, K.J. and Dietz, R.
Lancet 352 (9126): 489-489. 8 August 1998

Cardiac magnetic resonance monitors reversible and irreversible myocardial injury in myocarditis.
Zagrosek, A. and Abdel-Aty, H. and Boye, P. and Wassmuth, R. and Messroghli, D. and Utz, W. and Rudolph, A. and Bohl, S. and Dietz, R. and Schulz-Menger, J.
JACC: Cardiovascular Imaging 2 (2): 131-138. February 2009

Dittmar, Gunnar

Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K. and von Delbrück, M. and Dittmar, G. and Scheffner, M. and Ziv, I. and Glickman, M.H. and Ciechanover, A. and Sommer, T.
Molecular Cell 50 (4): 528-539. 23 May 2013

PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
Dittmar, G. and Perez Hernandez, D. and Kowenz-Leutz, E. and Kirchner, M. and Kahlert, G. and Wesolowski, R. and Baum, K. and Knoblich, M. and Hofstätter, M. and Muller, A. and Wolf, J. and Reimer, U. and Leutz, A.
iScience 13 : 351-370. 29 March 2019

Protein Interaction Screen on Peptide Matrix (PRISMA) reveals interaction footprints and the PTM-dependent interactome of intrinsically disordered C/EBPβ.
Dittmar, G. and Perez-Hernandez, D. and Kowenz-Leutz, E. and Kirchner, M. and Kahlert, G. and Wesolowski, R. and Baum, K. and Knoblich, M. and Muller, A. and Wolf, J. and Reimer, U. and Leutz, A.
bioRxiv : 238709. 22 December 2017

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. and Czajkowski, M.T. and Barth, C. and Müller, P.M. and McShane, E. and Grunwald, S. and Beaudette, P. and Mecklenburg, N. and Volkmer, R. and Zühlke, K. and Dittmar, G. and Selbach, M. and Hammes, A. and Daumke, O. and Klussmann, E. and Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease.
Guenther, U.P. and Handoko, L. and Varon, R. and Stephani, U. and Tsao, C.Y. and Mendell, J.R. and Lützkendorf, S. and Hübner, C. and von Au, K. and Jablonka, S. and Dittmar, G. and Heinemann, U. and Schuetz, A. and Schuelke, M.
Journal of Molecular Medicine 87 (1): 31-41. January 2009

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz, M. and Stilmann, M. and Coel Arslan, S. and Khanna, K.K. and Dittmar, G. and Scheidereit, C.
Molecular Cell 40 (1): 63-74. 8 October 2010

Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F. and a Dzaye, O.D. and Hahn, A. and Yu, Y. and Scavetta, R.J. and Dittmar, G. and Kaczmarek, A.K. and Dunning, K.R. and Ricciardelli, C. and Rinnenthal, J.L. and Heppner, F.L. and Lehnardt, S. and Synowitz, M. and Wolf, S.A. and Kettenmann, H.
Neuro-Oncology 17 (2): 200-210. February 2015

Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Kirchner, F. and Schuetz, A. and Boldt, L.H. and Martens, K. and Dittmar, G. and Haverkamp, W. and Thierfelder, L. and Heinemann, U. and Gerull, B.
Circulation Cardiovascular Genetics 5 (4): 400-411. 1 August 2012

Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.
Kowenz-Leutz, E. and Pless, O. and Dittmar, G. and Knoblich, M. and Leutz, A.
EMBO Journal 29 (6): 1105-1115. 17 March 2010

MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.
Krause, C.J. and Popp, O. and Thirunarayanan, N. and Dittmar, G. and Lipp, M. and Mueller, G.
Oncotarget 7 (9): 10414-10432. 1 March 2016

Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs.
Leutz, A. and Pless, O. and Lappe, M. and Dittmar, G. and Kowenz-Leutz, E.
Transcription 2 (1): 3-8. January 2011

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D. and Pahuja, A. and Geers-Knörr, C. and Scheibe, R. and Nowak, M. and Hamati, J. and Köhncke, C. and Purfürst, B. and Kanashova, T. and Schmidt, S. and Glass, D.J. and Morano, I. and Heuser, A. and Kraft, T. and Bassel-Duby, R. and Olson, E.N. and Dittmar, G. and Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180. May 2016

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N. and Kolesnichenko, M. and Beaudette, P. and Popp, O. and Uyar, B. and Sun, W. and Tufan, A.B. and Perder, B. and Akalin, A. and Chen, W. and Mertins, P. and Dittmar, G. and Hinz, M. and Scheidereit, C.
EMBO Journal 37 (24): e98658. 14 December 2018

Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M. and Fan, D.N.Y. and Belenki, D. and Däbritz, J.H.M. and Zhao, Z. and Yu, Y. and Dörr, J.R. and Dimitrova, L. and Lenze, D. and Monteiro Barbosa, I.A. and Mendoza-Parra, M.A. and Kanashova, T. and Metzner, M. and Pardon, K. and Reimann, M. and Trumpp, A. and Dörken, B. and Zuber, J. and Gronemeyer, H. and Hummel, M. and Dittmar, G. and Lee, S. and Schmitt, C.A.
Nature 553 (7686): 96-100. 4 January 2018

Translation of circRNAs.
Pamudurti, NR. and Bartok, O. and Jens, M. and Ashwal-Fluss, R. and Stottmeister, C. and Ruhe, L. and Hanan, M. and Wyler, E. and Perez-Hernandez, D. and Ramberger, E. and Shenzis, S. and Samson, M. and Dittmar, G. and Landthaler, M. and Chekulaeva, M. and Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

A differential proteome screening system for post-translational modification-dependent transcription factor interactions.
Pless, O. and Kowenz-Leutz, E. and Dittmar, G. and Leutz, A.
Nature Protocols 6 (3): 359-364. February 2011

Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K. and Shi, Y. and Jacobi, A. and Kräter, M. and Kalupa, M. and McGearey, A. and Mertlitz, S. and Cordes, S. and Schrezenmeier, J.F. and Mengwasser, J. and Westphal, S. and Perez-Hernandez, D. and Schmitt, C. and Dittmar, G. and Guck, J. and Penack, O.
Blood 129 (14): 2021-2032. 6 April 2017

Global analysis of cellular protein translation by pulsed SILAC.
Schwanhaeusser, B. and Gossen, M. and Dittmar, G. and Selbach, M.
Proteomics 9 (1): 205-209. January 2009

Ubiquitination.
Sommer, T. and Dittmar, G.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1964-1968. ISBN 3-540-44244-8 2006

RNF4-dependent oncogene activation by protein stabilization.
Thomas, J.J. and Abed, M. and Heuberger, J. and Novak, R. and Zohar, Y. and Beltra-Lopez, A.P. and Trausch-Azar, J.S. and Ilagan, M.X.G. and Benhamou, D. and Dittmar, G. and Kopan, R. and Birchmeier, W. and Schwartz, A.L. and Orian, A.
Cell Reports 16 (12): 3388-3400. 20 September 2016

Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A. and Cohen, I. and Popp, O. and Dittmar, G. and Reiss, Y. and Sommer, T. and Ravid, T. and Jarosch, E.
Molecular Cell 63 (5): 827-839. 1 September 2016

Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.
Yilmaz, Z.B. and Kofahl, B. and Beaudette, P. and Baum, K. and Ipenberg, I. and Weih, F. and Wolf, J. and Dittmar, G. and Scheidereit, C.
Cell Reports 9 (5): 1756-1769. 11 December 2014

Doerken, Bernd (MDC/ECRC)

Leukemia.
Bargou, R. and Ludwig, W.D.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 1. Springer, Berlin [u.a.], 967-974. ISBN 3-540-44244-8 2006

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
Bargou, R.C. and Emmerich, F. and Krappmann, D. and Bommert, K. and Mapara, M.Y. and Arnold, W. and Royer, H.D. and Grinstein, E. and Greiner, A. and Scheidereit, C. and Doerken, B.
Journal of Clinical Investigation 100 (12): 2961-2969. 15 December 1997

Characterization of a novel Hodgkin cell-line, HD-MyZ, HD-Myr, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.
Bargou, R.C. and Mapara, M.Y. and Zugck, C. and Daniel, P.T. and Pawlita, M. and Doehner, H. and Doerken, B.
Journal of Experimental Medicine 177 (5): 1257-1268. 1 May 1993

Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Arnold, W. and Daniel, P.T. and Mapara, M.Y. and Grinstein, E. and Royer, H.D. and Doerken, B.
Journal of Experimental Medicine 183 (3): 1205-1213. 1 March 1996

Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Mapara, M.Y. and Daniel, P.T. and Arnold, W. and Dietel, M. and Guski, H. and Feller, A. and Royer, H.D. and Doerken, B.
Journal of Clinical Investigation 97 (11): 2651-2659. 1 June 1996

Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K. and Goergen, H. and Hitz, F. and Zijlstra, J.M. and Greil, R. and Markova, J. and Sasse, S. and Fuchs, M. and Topp, M.S. and Soekler, M. and Mathas, S. and Meissner, J. and Wilhelm, M. and Koch, P. and Lindemann, H.W. and Schalk, E. and Semrau, R. and Kriz, J. and Vieler, T. and Bentz, M. and Lange, E. and Mahlberg, R. and Hassler, A. and Vogelhuber, M. and Hahn, D. and Mezger, J. and Krause, S.W. and Skoetz, N. and Böll, B. and von Tresckow, B. and Diehl, V. and Hallek, M. and Borchmann, P. and Stein, H. and Eich, H. and Engert, A.
Lancet 385 (9976): 1418-1427. 11 April 2015

CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.
Beltinger, C. and Kurz, E. and Boehler, T. and Schrappe, M. and Ludwig, W.D. and Debatin, K.M.
Blood 91 (10): 3943-3951. 15 May 1998

The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias.
Bene, M.C. and Bernier, M. and Casasnovas, R.O. and Castoldi, G. and Knapp, W. and Lanza, F. and Ludwig, W.D. and Matutes, E. and Orfao, A. and Sperling, C. and van't Veer, M.B.
Blood 92 (2): 596-599. 15 July 1998

Need for safety goggles for endoscopy.
Benter, T. and Kluehs, L. and Teichgraeber, U.K.M. and Riechert, F. and Ludwig, W.D. and Doerken, B.
Endoscopy 35 (9): 803. 1 September 2003

Therapie eines Zenker'schen Divertikels [Therapy of Zenker's divertikulum].
Benter, T. and Kretzschmar, A. and Reich, G. and Papadopoulos, S. and Kluhs, L. and Ludwig, W.D. and Doerken, B.
Medizinische Klinik 97 (1): 44-45. January 2002

Anatomical variations in the internal jugular veins of cancer patients affecting central venous access. Anatomical variation of the internal jugular vein.
Benter, T. and Teichgraeber, U.K. and Kluehs, L. and Papadopoulos, S. and Koehne, C.H. and Felix, R. and Doerken, B.
Ultraschall in der Medizin 22 (1): 23-26. February 2001

Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia.
Berenstein, R. and Blau, I.W. and Suckert, N. and Baldus, C. and Pezzutto, A. and Dörken, B. and Blau, O.
Journal of Experimental & Clinical Cancer Research 34 (1): 55. 22 May 2015

Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region.
Berenstein, R. and Blau, O. and Nogai, A. and Waechter, M. and Slonova, E. and Schmidt-Hieber, M. and Kunitz, A. and Pezzutto, A. and Doerken, B. and Blau, I.W.
BMC Cancer 15 (1): 68. 18 February 2015

Multiple myeloma cells modify VEGF/IL-6 levels and osteogenic potential of bone marrow stromal cells via Notch/miR-223.
Berenstein, R. and Nogai, A. and Waechter, M. and Blau, O. and Kuehnel, A. and Schmidt-Hieber, M. and Kunitz, A. and Pezzutto, A. and Dörken, B. and Blau, I.W.
Molecular Carcinogenesis 55 (12): 1927-1939. December 2016

YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification.
Bergmann, S. and Royer-Pokora, B. and Fietze, E. and Juerchott, K. and Hildebrandt, B. and Trost, D. and Leenders, F. and Claude, J.C. and Theuring, F. and Bargou, R. and Dietel, M. and Royer, H.D.
Cancer Research 65 (10): 4078-4087. 16 May 2005

Clinical features and outcome of children with first marrow relapse of acute lymphoblastic leukemia expressing BCR-ABL fusion transcripts.
Beyermann, B. and Agthe, A.G. and Adams, H.P. and Seeger, K. and Linderkamp, C. and Goetze, G. and Ludwig, W.D. and Henze, G.
Blood 87 (4): 1532-1538. 15 February 1996

Lebendvakzine zur Behandlung von Tumorerkrankungen [Live vaccine for the treatment of tumour diseases].
T. Blankenstein, S. Cayeux.
EP0777499A1 ; EP0777499B1 ; WO9605866A2 ; WO9605866A3 ; US6,039,941. 11 June 1997

Cytolysis of leukemic B-cells by T-cells activated via 2 bispecific antibodies.
Bohlen, H. and Manzke, O. and Patel, B. and Moldenhauer, G. and Doerken, B. and von Fliedner, V. and Diehl, V. and Tesch, H.
Cancer Research 53 (18): 4310-4314. 15 September 1993

Treatment of brain metastases in patients with testicular cancer.
Bokemeyer, C. and Nowak, P. and Haupt, A. and Metzner, B. and Koehne, H. and Hartmann, J.T. and Kanz, L. and Schmoll, H.J.
Journal of Clinical Oncology 15 (4): 1449-1454. April 1997

Eight cycles of escalated-dose BEACOPP compared with four cycles of escalated-dose BEACOPP followed by four cycles of baseline-dose BEACOPP with or without radiotherapy in patients with advanced-stage Hodgkin's lymphoma: final analysis of the HD12 trial of the German Hodgkin study group.
Borchmann, P. and Haverkamp, H. and Diehl, V. and Cerny, T. and Markova, J. and Ho, A.D. and Eich, H.T. and Mueller-Hermelink, H.K. and Kanz, L. and Greil, R. and Rank, A. and Paulus, U. and Smardova, L. and Huber, C. and Doerken, B. and Nerl, C. and Krause, S.W. and Mueller, R.P. and Fuchs, M. and Engert, A.
Journal of Clinical Oncology 29 (32): 4234-4342. 10 November 2011

Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M. and Lee, S. and Loddenkemper, C. and Rudolph, C. and Peters, A.H. and Schlegelberger, B. and Stein, H. and Doerken, B. and Jenuwein, T. and Schmitt, C.A.
Nature 436 (7051): 660-665. 4 August 2005

Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.
Breit, T.M. and Mol, E.J. and Wolvers-Tettero, I.L. and Ludwig, W.D. and van Wering, E.R. and van Dongen, J.J.
Journal of Experimental Medicine 177 (4): 965-977. 1 April 1993

Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line - cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.
Brockstedt, E. and Rickers, A. and Kostka, S. and Laubersheimer, A. and Doerken, B. and Wittmann-Liebold, B. and Bommert, K. and Otto, A.
Journal of Biological Chemistry 273 (43): 28057-28064. 23 October 1998

6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group.
Buechner, T. and Hiddemann, W. and Berdel, W.E. and Woermann, B. and Schoch, C. and Fonatsch, C. and Loeffler, H. and Haferlach, T. and Ludwig, W.D. and Maschmeyer, G. and Staib, P. and Aul, C. and Grueneisen, A. and Lengfelder, E. and Frickhofen, N. and Kern, W. and Serve, H.L. and Mesters, R.M. and Sauerland, M.C. and Heinecke, A.
Journal of Clinical Oncology 21 : 4496-4504. 15 December 2003

The receptor tyrosine kinase p185HER2 is expressed on a subset of B-lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia.
Buehring, H.J. and Sures, I. and Jallal, B. and Weiss, F.U. and Busch, F.W. and Ludwig, W.D. and Handgretinger, R. and Waller, H.D. and Ullrich, A.
Blood 86 (5): 1916-1923. 1 September 1995

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P. and Sasaki, Y. and Godinho, S.A. and Pellerin, A. and Köchert, K. and Sleckman, B.P. and de Alboran, I.M. and Janz, M. and Rodig, S. and Rajewsky, K.
Nature Immunology 13 (11): 1092-1100. November 2012

In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine.
Cayeux, S. and Bukarica, B. and Buschow, C. and Charo, J. and Bunse, M. and Doerken, B. and Blankenstein, T.
Gene Therapy 14 (20): 1481-1491. October 2007

STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
Chatterjee, M. and Jain, S. and Stuehmer, T. and Andrulis, M. and Ungethuem, U. and Kuban, R.J. and Lorentz, H. and Bommert, K. and Topp, M. and Kramer, D. and Mueller-Hermelink, H. K. and Einsele, H. and Greiner, A. and Bargou, R.C.
Blood 109 (2): 720-728. 15 January 2007

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M. and Stuehmer, T. and Herrmann, P. and Bommert, K. and Doerken, B. and Bargou, R.C.
Blood 104 (12): 3712-3721. 1 January 2004

Rituximab in the management of post-transplantation lymphoproliferative disorder after solid organ transplantation: proceed with caution.
Choquet, S. and Oertel, S. and Leblond, V. and Riess, H. and Varoqueaux, N. and Doerken, B. and Trappe, R.
Annals of Hematology 86 (8): 599-607. August 2007

Role of cranial radiotherapy for childhood T-cell acute lymphobalstic leukemia with high WBC count and good response to prednisone.
Conter, V. and Schrappe, M. and Arico, M. and Reiter, A. and Rizzari, C. and Doerdelmann, M. and Valsecchi, M.G. and Zimmermann, M. and Ludwig, W.D. and Basso, G. and Masera, G. and Riehm, H.
Journal of Clinical Oncology 15 (8): 2786-2791. August 1997

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.
Corral, J. and Forster, A. and Thompson, S. and Lampert, F. and Kaneko, Y. and Slater, R. and Kroes, W.G. and van der Schoot, C.E. and Ludwig, W.D. and Karpas, A. and Pocock, C. and Cotter, F. and Rabitts, T.H.
Proceedings of the National Academy of Sciences of the United States of America 90 (18): 8538-8542. 15 September 1993

Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Creutzig, U. and Harbott, J. and Sperling, C. and Ritter, J. and Zimmermann, M. and Loeffler, H. and Riehm, H. and Schellong, G. and Ludwig, W.D.
Blood 86 (8): 3097-3108. 1 October 1995

Grundlagen der molekularen Diagnostik und Therapie maligner Tumoren [Basics of molecular diagnostics and therapy of malignant tumors].
Daniel, P.T. and Doerken, B.
Internist 46 (8): 835-846. 12 July 2005

Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T. and Kroidl, A. and Kopp, J. and Sturm, I. and Moldenhauer, G. and Doerken, B. and Pezzutto, A.
Blood 92 (12): 4750-4757. 15 December 1998

Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.
Daniel, P.T. and Kroidl, A. and Cayeux, S. and Bargou, R.C. and Blankenstein, T. and Doerken, B.
Journal of Immunology 159 (8): 3808-3815. 15 October 1997

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E. and Herzog, S. and Labi, V. and Yasuda, T. and Köchert, K. and Janz, M. and Villunger, A. and Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5065-5070. 3 May 2016

Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkins disease.
Diehl, V. and Franklin, J. and Pfreundschuh, M. and Lathan, B. and Paulus, U. and Hasenclever, D. and Tesch, H. and Herrmann, R. and Doerken, B. and Mueller-Hermelink, H.K. and Duehmke, E. and Loeffler, M.
New England Journal of Medicine 348 (24): 2386-2395. 12 June 2003

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
Ding, Q. and Xia, W. and Liu, J.C. and Yang, J.Y. and Lee, D.F. and Xia, J. and Bartholomeusz, G. and Li, Y. and Pan, Y. and Li, Z. and Bargou, R.C. and Qin, J. and Lai, C.C. and Tsai, F.J. and Tsai, C.H. and Hung, M.C.
Molecular Cell 19 : 159-170. 1 January 2005

MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis.
Dreyling, M.H. and Schrader, K. and Fonatsch, C. and Schlegelberger, B. and Haase, D. and Schoch, C. and Ludwig, W.D. and Loeffler, H. and Buechner, T. and Wormann, B. and Hiddemann, W. and Bohlander, S.K.
Blood 91 (12): 4662-4667. 15 June 1998

HCMV-encoded chemokine receptor US28 employs multiple routes for internalization.
Droese, J. and Mokros, T. and Hermosilla, R. and Schuelein, R. and Lipp, M. and Hoepken, U.E. and Rehm, A.
Biochemical and Biophysical Research Communications 322 (1): 42-49. 10 September 2004

CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma.
Däbritz, J.H.M. and Yu, Y. and Milanovic, M. and Schönlein, M. and Rosenfeldt, M.T. and Dörr, J.R. and Kaufmann, A.M. and Dörken, B. and Schmitt, C.A.
Molecular Cancer Therapeutics 15 (5): 1074-1081. May 2016

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr, J.R. and Yu, Y. and Milanovic, M. and Beuster, G. and Zasada, C. and Däbritz, J.H.M. and Lisec, J. and Lenze, D. and Gerhardt, A. and Schleicher, K. and Kratzat, S. and Purfürst, B. and Walenta, S. and Mueller-Klieser, W. and Gräler, M. and Hummel, M. and Keller, U. and Buck, A.K. and Dörken, B. and Willmitzer, L. and Reimann, M. and Kempa, S. and Lee, S. and Schmitt, C.A.
Nature 501 (7467): 421-425. 19 September 2013

Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial.
Eich, H.T. and Diehl, V. and Goergens, H. and Pabst, T. and Markova, J. and Debus, J. and Ho, A. and Doerken, B. and Rank, A. and Grosu, A.L. and Wiegel, T. and Karstens, J.H. and Greil, R. and Willich, N. and Schmidberger, H. and Doehner, H. and Borchmann, P. and Mueller-Hermelink, H.K. and Mueller, R.P. and Engert, A.
Journal of Clinical Oncology 28 (27): 4199-4206. 20 September 2010

IkappaBalpha is required for marginal zone B cell lineage development.
Ellinghaus, U. and Rupec, R.A. and Pabst, O. and Ignatius, R. and Foerster, R. and Doerken, B. and Jundt, F.
European Journal of Immunology 38 (8): 2096-2105. August 2008

Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells.
Emmerich, F. and Theurich, S. and Hummel, M. and Haeffker, A. and Vry, M.S. and Doehner, K. and Bommert, K. and Stein, H. and Doerken, B.
Journal of Pathology 201 (3): 413-420. November 2003

The Golgi protein RCAS1 controls cell surface expression of tumor-associated O-linked glycan antigens.
Engelsberg, A. and Hermosilla, R. and Karsten, U. and Schuelein, R. and Doerken, B. and Rehm, A.
Journal of Biological Chemistry 278 (25): 22998-23007. 1 January 2003

Escalated-dose BEACOPP in the treatment of patients with advanced-stage Hodgkin's lymphoma: 10 years of follow-up of the GHSG HD9 study.
Engert, A. and Diehl, V. and Franklin, J. and Lohri, A. and Doerken, B. and Ludwig, W.D. and Koch, P. and Haenel, M. and Pfreundschuh, M. and Wilhelm, M. and Truemper, L. and Aulitzky, W.E. and Bentz, M. and Rummel, M. and Sezer, O. and Mueller-Hermelink, H.K. and Hasenclever, D. and Loeffler, M.
Journal of Clinical Oncology 27 (27): 4548-4554. 20 September 2009

Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.
Engert, A. and Haverkamp, H. and Kobe, C. and Markova, J. and Renner, C. and Ho, A. and Zijlstra, J. and Kral, Z. and Fuchs, M. and Hallek, M. and Kanz, L. and Doehner, H. and Doerken, B. and Engel, N. and Topp, M. and Klutmann, S. and Amthauer, H. and Bockisch, A. and Kluge, R. and Kratochwil, C. and Schober, O. and Greil, R. and Andreesen, R. and Kneba, M. and Pfreundschuh, M. and Stein, H. and Eich, H.T. and Mueller, R.P. and Dietlein, M. and Borchmann, P. and Diehl, V.
Lancet 379 (9828): 1791-1799. 12 May 2012

Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.
Engert, A. and Pluetschow, A. and Eich, H.T. and Lohri, A. and Doerken, B. and Borchmann, P. and Berger, B. and Greil, R. and Willborn, K.C. and Wilhelm, M. and Debus, J. and Eble, M.J. and Soekler, M. and Ho, A. and Rank, A. and Ganser, A. and Truemper, L. and Bokemeyer, C. and Kirchner, H. and Schubert, J. and Kral, Z. and Fuchs, M. and Mueller-Hermelink, H.K. and Mueller, R.P. and Diehl, V.
New England Journal of Medicine 363 (7): 640-652. 12 August 2010

Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli, U.M. and Ullrich, K. and Stuehmer, T. and Holien, T. and Koechert, K. and Holt, R.U. and Bruland, O. and Chatterjee, M. and Nogai, H. and Lenz, G. and Shaughnessy, J.D. and Mathas, S. and Sundan, A. and Bargou, R.C. and Doerken, B. and Borset, M. and Janz, M.
Oncogene 30 (28): 3198-3206. 14 July 2011

Long-lasting remission of pulmonary metastases of renal cell cancer under IFN-beta therapy in a patient with multiple sclerosis.
Floercken, A. and Denecke, T. and Kretzschmar, A. and Gollasch, H. and Reich, G. and Westermann, J.
Onkologie 29 : 382-384. September 2006

Severe thrombocytopenia in a patient with metastatic renal cell carcinoma.
Floercken, A. and Loew, A. and Koch, M. and Gebauer, B. and Doerken, B. and Riess, H.
Onkologie 32 (11): 670-672. November 2009

Hepatic arterial infusion chemotherapy for liver metastases from gastric cancer: an analysis in western patients.
Floercken, A. and Schaefer, C. and Bichev, D. and Breithaupt, K. and Dogan, Y. and Schumacher, G. and Gebauer, B. and Riess, H. and Doerken, B. and Thuss-Patience, P.C.
Tumori 97 (1): 19-24. January 2011

DC generation from peripheral blood mononuclear cells in patients with chronic myeloid leukemia: Influence of interferons on DC yield and functional properties.
Floercken, A. and Kopp, J. and Kölsch, U. and Meisel, C. and Dörken, B. and Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 12 (5): 1117-1123. 3 May 2016

Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken, A. and Grau, M. and Wolf, A. and Weilemann, A. and Kopp, J. and Dörken, B. and Blankenstein, T. and Pezzutto, A. and Lenz, P. and Lenz, G. and Westermann, J.
International Journal of Cancer 136 (8): 1814-1826. 15 April 2015

Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study.
Flörcken, A. and Kopp, J. and van Lessen, A. and Movassaghi, K. and Takvorian, A. and Jöhrens, K. and Möbs, M. and Schönemann, C. and Sawitzki, B. and Egerer, K. and Dörken, B. and Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9 (7): 1217-1227. 1 June 2013

Myeloid-derived suppressor cells in human peripheral blood: optimized quantification in healthy donors and patients with metastatic renal cell carcinoma.
Flörcken, A. and Takvorian, A. and Singh, A. and Gerhardt, A. and Ostendorf, B.N. and Dörken, B. and Pezzutto, A. and Westermann, J.
Immunology Letters 168 (2): 260-267. December 2015

Anti-leukemia T cells in AML: TNF-α(+) CD8(+) T cells may escape detection and possibly reflect a stage of functional impairment.
Flörcken, A. and van Lessen, A. and Terwey, T.H. and Dörken, B. and Arnold, R. and Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9 (7): 1200-1204. 1 June 2013

New insights into the biology of molecular subtypes of diffuse large B-cell lymphoma and Burkitt lymphoma.
Frick, M. and Doerken, B. and Lenz, G.
Best Practice and Research Clinical Haematology 25 (1): 3-12. March 2012

The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.
Fuchs, U. and Rehkamp, G. and Haas, O.A. and Slany, R. and Konig, M. and Bojesen, S. and Bohle, R.M. and Damm-Welk, C. and Ludwig, W.D. and Harbott, J. and Borkhardt, A.
Proceedings of the National Academy of Sciences of the United States of America 98 (15): 8756-8761. 17 July 2001

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
Gillissen, B. and Essmann, F. and Graupner, V. and Staerck, L. and Radetzki, S. and Doerken, B. and Schulze-Osthoff, K. and Daniel, P.T.
EMBO Journal 22 (14): 3580-3590. 15 July 2003

Recombinant human erythropoietin, epoetin beta, in patients with relapsed lymphoma treated with aggressive sequential salvage chemotherapy - results of a randomized trial.
Glossmann, J.P. and Engert, A. and Wassmer, G. and Flechtner, H. and Ko, Y. and Rudolph, C. and Metzner, B. and Doerken, B. and Wiedenmann, S. and Diehl, V. and Josting, A.
Annals of Hematology 82 (8): 469-475. 1 August 2003

Prognostic value of multimarker analysis in stage III colorectal cancer: one step forward towards an individualized therapy decision.
Grabowski, P. and Maaser, K. and Hanski, C. and Stein, H. and Sturm, I. and Hopfenmueller, W. and Doerken, B. and Buhr, H.J. and Zeitz, M. and Scheruebl, H.
Onkologie 28 (8-9): 399-403. 1 August 2005

T-cell-mediated lysis of B cells induced by a CD19xCD3 bispecific single-chain antibody is perforin dependent and death receptor independent.
Gruen, M. and Bommert, K. and Bargou, R.C.
Cancer Immunology Immunotherapy 53 (7): 625-632. 1 January 2004

Disruption of cell death signaling in cancer: impact on disease prognosis and response to therapy.
Guener, D. and Belka, C. and Daniel, P.T.
Current Medicinal Chemistry Anti-Cancer Agents 3 (5): 319-326. 1 September 2003

Morphologic dysplasia in de novo acute myeloid leukemia (AML) is related to unfavorable cytogenetics but has no independent prognostic relevance under the conditions of intensive induction therapy: results of a multiparameter analysis from the German AML Cooperative Group studies.
Haferlach, T. and Schoch, C. and Loeffler, H. and Gassmann, W. and Kern, W. and Schnittger, S. and Fonatsch, C. and Ludwig, W.D. and Wuchter, C. and Schlegelberger, B. and Staib, P. and Reichle, A. and Kubica, U. and Eimermacher, H. and Balleisen, L. and Grueneisen, A. and Haase, D. and Aul, C. and Karow, J. and Lengfelder, E. and Woermann, B. and Heinecke, A. and Sauerland, M.C. and Buechner, T. and Hiddemann, W.
Journal of Clinical Oncology 21 : 256-265. 15 January 2003

Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines.
Hailfinger, S. and Nogai, H. and Pelzer, C. and Jaworski, M. and Cabalzar, K. and Charton, J.E. and Guzzardi, M. and Decaillet, C. and Grau, M. and Doerken, B. and Lenz, P. and Lenz, G. and Thome, M.
Proceedings of the National Academy of Sciences of the United States of America 108 (35): 14596-14601. 30 August 2011

Cellular senescence predicts treatment outcome in metastasised colorectal cancer.
Haugstetter, A.M. and Loddenkemper, C. and Lenze, D. and Groene, J. and Standfuss, C. and Petersen, I. and Doerken, B. and Schmitt, C.A.
British Journal of Cancer 103 (4): 505-509. 10 August 2010

An individual patient-data comparison of combined modality therapy and ABVD alone for patients with limited-stage Hodgkin lymphoma.
Hay, A.E. and Klimm, B. and Chen, B.E. and Goergen, H. and Shepherd, L.E. and Fuchs, M. and Gospodarowicz, M.K. and Borchmann, P. and Connors, J.M. and Markova, J. and Crump, M. and Lohri, A. and Winter, J.N. and Doerken, B. and Pearcey, R.G. and Diehl, V. and Horning, S.J. and Eich, H.T. and Engert, A. and Meyer, R.M.
Annals of Oncology 24 (12): 3065-3069. December 2013

Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
Heinig, K. and Gätjen, M. and Grau, M. and Stache, V. and Anagnostopoulos, I. and Gerlach, K. and Niesner, R.A. and Cseresnyes, Z. and Hauser, A.E. and Lenz, P. and Hehlgans, T. and Brink, R. and Westermann, J. and Dörken, B. and Lipp, M. and Lenz, G. and Rehm, A. and Höpken, U.E.
Cancer Discovery 4 : 1448-1465. December 2014

Cytogenetic risk grouping by the monosomal karyotype classification is superior in predicting the outcome of acute myeloid leukemia undergoing allogeneic stem cell transplantation in complete remission.
Hemmati, P.G. and Schulze-Luckow, A. and Terwey, T.H. and le Coutre, P. and Vuong, L.G. and Doerken, B. and Arnold, R.
European Journal of Haematology 92 (2): 102-110. February 2014

Reduced intensity conditioning prior to allogeneic stem cell transplantation in first complete remission is effective in patients with acute myeloid leukemia and an intermediate-risk karyotype.
Hemmati, P.G. and Terwey, T.H. and Massenkeil, G. and le Coutre, P. and Vuong, L.G. and Neuburger, S. and Doerken, B. and Arnold, R.
International Journal of Hematology 91 (3): 436-445. April 2010

Allogeneic stem cell transplantation for refractory acute myeloid leukemia: a single center analysis of long-term outcome.
Hemmati, P.G. and Terwey, T.H. and Na, I.K. and Jehn, C.F. and le Coutre, P. and Vuong, L.G. and Doerken, B. and Arnold, R.
European Journal of Haematology 95 (6): 498-506. December 2015

A modified EBMT risk score predicts the outcome of patients with acute myeloid leukemia receiving allogeneic stem cell transplants.
Hemmati, P.G. and Terwey, T.H. and le Coutre, P. and Vuong, L.G. and Massenkeil, G. and Doerken, B. and Arnold, R.
European Journal of Haematology 86 (4): 305-316. April 2011

Impact of early remission by induction therapy on allogeneic stem cell transplantation for acute myeloid leukemia with an intermediate risk karyotype in first complete remission.
Hemmati, P.G. and Terwey, T.H. and Na, I.K. and le Coutre, P. and Jehn, C.F. and Vuong, L.G. and Dörken, B. and Arnold, R.
European Journal of Haematology 94 (5): 431-438. May 2015

Intraoperative fresh-frozen plasma versus human albumin in craniofacial surgery - a pilot study comparing coagulation profiles in infants younger than 12 months.
Hildebrandt, B. and Machotta, A. and Riess, H. and Kerner, S. and Ahlers, O. and Haberl, H. and Doerken, B. and Kerner, T.
Thrombosis and Haemostasis 98 (1): 172-7. July 2007

Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: A phase II-study and historical comparison with the surgical approach.
Hildebrandt, B. and Pech, M. and Nicolaou, A. and Langrehr, J.M. and Kurcz, J. and Bartels, B. and Miersch, A. and Felix, R. and Neuhaus, P. and Riess, H. and Doerken, B. and Ricke, J.
BMC Cancer 7 : 69. 24 April 2007

Adjuvant chemotherapy with folinic acid and 5-fluorouracil in patients with locally advanced rectal cancer previously treated by preoperative radiochemotherapy and curative tumor resection.
Hildebrandt, B. and Rau, B. and Loeffel, J. and Wust, P. and Nicolaou, A. and Gellermann, J. and Le Coutre, P. and Neuhaus, P. and Felix, R. and Wernecke, K.D. and Doerken, B. and Riess, H.
International Journal of Colorectal Disease 21 (6): 582-589. September 2006

Clinical research and industrial sponsoring: avenues towards transparency and credibility.
Hildebrandt, M. and Ludwig, W.D.
Onkologie 26 : 529-534. 1 December 2003

Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M. and Lemke, P. and Anagnostopoulos, I. and Hacker, C. and Krappmann, D. and Mathas, S. and Doerken, B. and Zenke, M. and Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196 (5): 605-617. 2 September 2002

Expression of a hypoglycosylated form of CD86 (B7-2) on human T cells with altered binding properties to CD28 and CTLA-4.
Hoellsberg, P. and Scholz, C. and Anderson, D.E. and Greenfield, E.A. and Kuchroo, V.K. and Freeman, G.J. and Hafler, D.A.
Journal of Immunology 159 (10): 4799-4805. 15 November 1997

A novel recombinant bispecific single-chain antibody, bscWue-1 x CD3, induces T-cell-mediated cytotoxicity towards human multiple myeloma cells.
Hoenemann, D. and Kufer, P. and Rimpler, M.M. and Chatterjee, M. and Friedl, S. and Riecher, F. and Bommert, K. and Doerken, B. and Bargou, R.C.
Leukemia 18 (3): 636-644. 1 January 2004

The ratio between dendritic cells and T cells determines the outcome of their encounter: Proliferation versus deletion.
Hoepken, U.E. and Lehmann, I. and Droese, J. and Lipp, M. and Schueler, T. and Rehm, A.
European Journal of Immunology 35 (10): 2851-2863. 23 September 2005

Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs.
Hoepken, U.E. and Rehm, A.
Journal of Molecular Medicine 90 (11): 1237-1245. November 2012

CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
Hoepken, U.E. and Wengner, A.M. and Loddenkemper, C. and Stein, H. and Heimesaat, M.M. and Rehm, A. and Lipp, M.
Blood 109 (3): 886-895. 1 February 2007

Serial killing of tumor cells by cytotoxic T cells redirected with a CD19-/CD3-bispecific single-chain antibody construct.
Hoffmann, P. and Hofmeister, R. and Brischwein, K. and Brandl, C. and Crommer, S. and Bargou, R. and Itin, C. and Prang, N. and Baeuerle, P.A.
International Journal of Cancer 115 : 98-104. 1 January 2005

A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.
Hofgaard, P.O. and Jodal, H.C. and Bommert, K. and Huard, B. and Caers, J. and Carlsen, H. and Schwarzer, R. and Schuenemann, N. and Jundt, F. and Lindeberg, M.M. and Bogen, B.
PLoS ONE 7 (12): e51892. 20 December 2012

Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor.
Holdhoff, M. and Kreuzer, K.A. and Appelt, C. and Scholz, R. and Na, I.K. and Hildebrandt, B. and Riess, H. and Jordan, A. and Schmidt, C.A. and Van Etten, R.A. and Doerken, B. and LeCoutre, P.
Blood Cells Molecules and Diseases 34 (2): 181-185. 1 March 2005

Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission.
Janssen, J.W. and Ludwig, W.D. and Borkhardt, A. and Spadinger, U. and Rieder, H. and Fonatsch, C. and Hossfeld, D.K. and Harbott, J. and Schulz, A.S. and Repp, R. and Sykora, K.W. and Hoelzer, D. and Bartram, C.R.
Blood 84 (11): 3835-3842. 1 December 1994

Reprogramming of B lymphoid cells in human lymphoma pathogenesis.
Janz, M. and Doerken, B. and Mathas, S.
Cell Cycle 5 (10): 1057-1061. 15 May 2006

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M. and Hummel, M. and Truss, M. and Wollert-Wulf, B. and Mathas, S. and Joehrens, K. and Hagemeier, C. and Bommert, K. and Stein, H. and Doerken, B. and Bargou, R.C.
Blood 107 (6): 2536-2539. 15 March 2006

The pathogenesis of classical Hodgkin's lymphoma: what can we learn from analyses of genomic alterations in Hodgkin and Reed-Sternberg cells?
Janz, M. and Mathas, S.
Haematologica 93 (9): 1292-1295. September 2008

Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells.
Janz, M. and Stuehmer, T. and Vassilev, L.T. and Bargou, R.C.
Leukemia 21 (4): 772-779. April 2007

Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H. and Kase, J. and Doerr, J.R. and Milanovic, M. and Lenze, D. and Grau, M. and Beuster, G. and Ji, S. and Reimann, M. and Lenz, P. and Hummel, M. and Doerken, B. and Lenz, G. and Scheidereit, C. and Schmitt, C.A. and Lee, S.
Genes & Development 25 (20): 2137-2146. 15 October 2011

Morphologie gastrointestinaler Stromatumoren im fortgeschrittenen Stadium der Erkrankung: Ausgangsbefunde vor Chemotherapie mit Imatinib [Morphology of gastrointestinal stromal tumors in advanced stages of the disease: baseline findings before chemotherapy with imatinib].
Jost, D. and Stroszczynski, C. and Chmelik, P. and Gaffke, G. and Schlecht, I. and Pink, D. and Reichardt, P. and Schneider, U. and Hohenberger, P. and Felix, R.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 175 : 791-798. 1 June 2003

Cologne high-dose sequential chemotherapy in relapsed and refractory Hodgkin lymphoma: results of a large multicenter study of the German Hodgkin Lymphoma Study Group (GHSG).
Josting, A. and Rudolph, C. and Mapara, M. and Glossmann, J.P. and Sieniawski, M. and Sieber, M. and Kirchner, H.H. and Doerken, B. and Hossfeld, D.K. and Kisro, J. and Metzner, B. and Berdel, W.E. and Diehl, V. and Engert, A.
Annals of Oncology 16 : 116-123. 1 January 2005

High-dose sequential chemotherapy followed by autologous stem cell transplantation in relapsed and refractory aggressive non-Hodgkin's lymphoma: results of a multicenter phase II study.
Josting, A. and Sieniawski, M. and Glossmann, J.P. and Staak, O. and Nogova, L. and Peters, N. and Mapara, M. and Doerken, B. and Ko, Y. and Metzner, B. and Kisro, J. and Diehl, V. and Engert, A.
Annals of Oncology 16 : 1359-1365. 1 January 2005

Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma.
Jundt, F. and Acikgoez, O. and Kwon, S.H. and Schwarzer, R. and Anagnostopoulos, I. and Wiesner, B. and Mathas, S. and Hummel, M. and Stein, H. and Reichardt, H.M. and Doerken, B.
Leukemia 22 (8): 1587-1594. August 2008

Trimethoprim-sulfamethoxazole exacerbates posthypoxic action myoclonus in a patient with suspicion of Pneumocystis jiroveci infection.
Jundt, F. and Lempert, T. and Doerken, B. and Pezzutto, A.
Infection 32 (3): 176-178. 1 June 2004

A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F. and Raetzel, N. and Mueller, C. and Calkhoven, C.F. and Kley, K. and Mathas, S. and Lietz, A. and Leutz, A. and Doerken, B.
Blood 106 : 1801-1807. 1 January 2005

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F. and Schulze-Proebsting, K. and Anagnostopoulos, I. and Muehlinghaus, G. and Chatterjee, M. and Mathas, S. and Bargou, R.C. and Manz, R. and Stein, H. and Doerken, B.
Blood 103 (9): 3511-3515. 1 January 2004

Notch signaling in leukemias and lymphomas.
Jundt, F. and Schwarzer, R. and Doerken, B.
Current Molecular Medicine 8 (1): 51-59. February 2008

JAK2 V617F allele burden quantified by real time quantitative polymerase chain reaction and competitive polymerase chain reaction in patients with chronic myeloproliferative neoplasia.
Kaeda, J. and Bonamino, M. and Ayres-Silva, J. and Solza, C. and Ringel, F. and Blau, O. and Daumas, A. and Oberender, C. and Doerken, B. and Le Coutre, P. and Zalcberg, I.
Leukemia & Lymphoma 55 (1): 128-135. January 2014

Differential expression of SHP-1 in chronic myeloid leukemia.
Kaeda, J. and Neuman, D. and Bonecker, S. and Mills, K. and Oberender, C. and Amini, L. and Ringel, F. and Serra, A. and Schwarz, M. and Doerken, B. and Zalcberg, I. and Le Coutre, P.
Leukemia & Lymphoma 56 (5): 1547-1549. May 2015

Longitudinal study to assess the clinical significance of MSI2 expression in chronic myeloid keukemia patients.
Kaeda, J. and Ringel, F. and Oberender, C. and Gresse, M. and Amini, L. and Schwarz, M. and Doerken, B. and le Coutre, P.
Acta Haematologica 136 (1): 62-64. June 2016

Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.
Kaeda, J. and Ringel, F. and Oberender, C. and Mills, K. and Quintarelli, C. and Pane, F. and Koschmieder, S. and Slany, R. and Schwarzer, R. and Saglio, G. and Hemmati, P. and van Lessen, A. and Amini, L. and Greese, M. and Vagge, E. and Burmeister, T. and Serra, A. and Carson, A. and Schwarz, M. and Westermann, J. and Jundt, F. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 56 (7): 2105-2113. July 2015

Cellular senescence in cancer treatment: friend or foe?
Kahlem, P. and Doerken, B. and Schmitt, C.A.
Journal of Clinical Investigation 113 (2): 169-174. January 2004

Detection of minimal residual disease in unselected patients with acute myeloid leukemia using multiparameter flow cytometry for definition of leukemia-associated immunophenotypes and determination of their frequencies in normal bone marrow.
Kern, W. and Danhauser-Riedl, S. and Ratei, R. and Schnittger, S. and Schoch, C. and Kolb, H.J. and Ludwig, W.D. and Hiddemann, W. and Haferlach, T.
Haematologica 88 : 646-653. 1 June 2003

Correlation of protein expression and gene expression in acute leukemia.
Kern, W. and Kohlmann, A. and Wuchter, C. and Schnittger, S. and Schoch, C. and Mergenthaler, S. and Ratei, R. and Ludwig, W.D. and Hiddemann, W. and Haferlach, T.
Cytometry 55B : 29-36. 1 September 2003

Peripheral artery occlusive disease (PAOD) in chronic phase chronic myeloid leukemia patients treated with nilotinib or Imatinib.
Kim, T.D. and Rea, D. and Schwarz, M. and Grille, P. and Nicolini, F.E. and Rosti, G. and Levato, L. and Giles, F.J. and Dombret, H. and Mirault, T. and Labussiere, H. and Lindhorst, R. and Haverkamp, W. and Buschmann, I. and Doerken, B. and le Coutre, P.D.
Leukemia 27 (6): 1316-1321. 5 April 2013

Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D. and Schwarz, M. and Nogai, H. and Grille, P. and Westermann, J. and Ploeckinger, U. and Braun, D. and Schweizer, U. and Arnold, R. and Doerken, B. and le Coutre, P.
Thyroid 20 (11): 1209-1214. 9 November 2010

Clinical cardiac safety profile of nilotinib.
Kim, T.D. and le Coutre, P. and Schwarz, M. and Grille, P. and Levitin, M. and Fateh-Moghadam, S. and Giles, F.J. and Doerken, B. and Haverkamp, W. and Koehncke, C.
Haematologica 97 (6): 883-889. June 2012

Critical role of PI3K signaling for NF-κB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.
Kloo, B. and Nagel, D. and Pfeifer, M. and Grau, M. and Duewel, M. and Vincendeau, M. and Doerken, B. and Lenz, P. and Lenz, G. and Krappmann, D.
Proceedings of the National Academy of Sciences of the United States of America 108 (1): 272-277. 4 January 2011

Genauigkeit der sonographischen Milzgewichtsbestimmung am Lebenden im Vergleich zum pathologischen Korrelat [Accuracy of the sonographic determination of the splenic weight in comparison with the weight at autopsy].
Kluehs, L. and Teichgraeber, U.K. and Schneider, U. and Ludwig, W.D. and Doerken, B. and Benter, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 175 (4): 532-535. 1 April 2003

High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
Koechert, K. and Ullrich, K. and Kreher, S. and Aster, J.C. and Kitagawa, M. and Joehrens, K. and Anagnostopoulos, I. and Jundt, F. and Lamprecht, B. and Zimber-Strobl, U. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Oncogene 30 (15): 1831-1840. 14 April 2011

Effective biomodulation by leucovorin of high-dose infusion fluorouracil given as a weekly 24-hour infusion: results of a randomized trial in patients with advanced colorectal cancer.
Koehne, C.H. and Schoeffski, P. and Wilke, H. and Kaeufer, C. and Andreesen, R. and Ohl, U. and Klaasen, U. and Westerhausen, M. and Hiddemann, W. and Schott, G. and Harstick, A. and Bade, J. and Horster, A. and Schubert, U. and Hecker, H. and Doerken, B. and Schmoll, H.J.
Journal of Clinical Oncology 16 (2): 418-426. February 1998

Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis.
Koh, K.R. and Janz, M. and Mapara, M.Y. and Lemke, B. and Stirling, D. and Doerken, B. and Zenke, M. and Lentzsch, S.
Blood 105 (10): 3833-3840. 1 January 2005

Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: its more than NF-κB!
Kreher, S. and Cauchy, P. and Bonifer, C. and Mathas, S.
Cytokine 72 (1): 115-117. March 2015

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S. and Bouhlel, M.A. and Cauchy, P. and Lamprecht, B. and Li, S. and Grau, M. and Hummel, F. and Köchert, K. and Anagnostopoulos, I. and Jöhrens, K. and Hummel, M. and Hiscott, J. and Wenzel, S.S. and Lenz, P. and Schneider, M. and Küppers, R. and Scheidereit, C. and Giefing, M. and Siebert, R. and Rajewsky, K. and Lenz, G. and Cockerill, P.N. and Janz, M. and Dörken, B. and Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111 (42): E4513-E4522. 21 October 2014

Extravasations of oxaliplatin.
Kretzschmar, A. and Pink, D. and Thuss-Patience, P. and Doerken, B. and Reichert, P. and Eckert, R.
Journal of Clinical Oncology 21 (21): 4068-4069. 1 November 2003

Weekly 24-Hour infusion of high-dose 5-fluorouracil plus folinic acid in combination with mitomycin C for the treatment of advanced gastric cancer.
Kretzschmar, A. and Reichardt, P. and Thuss-Patience, P.C. and Hohenberger, P. and Benter, T. and Doerken, B. and Koehne, C.H.
Oncology 59 (1): 14-17. June 2000

Filgrastim-induced stem cell mobilization in chronic myeloid leukaemia patients during imatinib therapy: safety, feasibility and evidence for an efficient in vivo purging.
Kreuzer, K.A. and Kluehs, C. and Baskaynak, G. and Movassaghi, K. and Doerken, B. and Le Coutre, P.
British Journal of Haematology 124 (2): 195-199. 1 January 2004

Repeat-element driven activation of proto-oncogenes in human malignancies.
Lamprecht, B. and Bonifer, C. and Mathas, S.
Cell Cycle 9 (21): 4276-4281. November 2010

Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B. and Kreher, S. and Anagnostopoulos, I. and Joehrens, K. and Monteleone, G. and Jundt, F. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Blood 112 (8): 3339-3347. 15 October 2008

The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome.
Lamprecht, B. and Kreher, S. and Moebs, M. and Sterry, W. and Doerken, B. and Janz, M. and Assaf, C. and Mathas, S.
British Journal of Dermatology 167 (2): 240-246. August 2012

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B. and Walter, K. and Kreher, S. and Kumar, R. and Hummel, M. and Lenze, D. and Koechert, K. and Bouhlel, M.A. and Richter, J. and Soler, E. and Stadhouders, R. and Joehrens, K. and Wurster, K.D. and Callen, D.F. and Harte, M.F. and Giefing, M. and Barlow, R. and Stein, H. and Anagnostopoulos, I. and Janz, M. and Cockerill, P.N. and Siebert, R. and Doerken, B. and Bonifer, C. and Mathas, S.
Nature Medicine 16 (5): 571-579, 1p following 579. May 2010

Pharmacokinetics and cellular uptake of imatinib and its main metabolite CGP74588.
Le Coutre, P. and Kreuzer, K.A. and Pursche, S. and Bonin, M. and Leopold, T. and Baskaynak, G. and Doerken, B. and Ehninger, G. and Ottmann, O. and Jenke, A. and Bornhaeuser, M. and Schleyer, E.
Cancer Chemotherapy and Pharmacology 53 (4): 313-323. 1 April 2004

Severe peripheral arterial disease during nilotinib therapy.
Le Coutre, P. and Rea, D. and Abruzzese, E. and Dombret, H. and Trawinska, M.M. and Herndlhofer, S. and Doerken, B. and Valent, P.
Journal of the National Cancer Institute 103 (17): 1347-1348. 7 September 2011

Chemotherapy response and resistance.
Lee, S. and Schmitt, C.A.
Current Opinion in Genetics & Development 13 (1): 90-96. February 2003

Immunomodulatory analogs of thalidomide inhibit growth of Hs Sultan cells and angiogenesis in vivo.
Lentzsch, S. and LeBlanc, R. and Podar, K. and Davies, F. and Lin, B. and Hideshima, T. and Catley, L. and Stirling, D.I. and Anderson, K.C.
Leukemia 17 : 41-44. 1 January 2003

PI3-K/AKT/FKHR and MAPK signaling cascades are redundantly stimulated by a variety of cytokines and contribute independently to proliferation and survival of multiple myeloma cells.
Lentzsch, S. and Chatterjee, M. and Gries, M. and Bommert, K. and Gollasch, H. and Doerken, B. and Bargou, R.C.
Leukemia 18 (11): 1883-1890. 1 January 2004

Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S. and Gries, M. and Janz, M. and Bargou, R. and Doerken, B. and Mapara, M.Y.
Blood 101 (9): 3568-3573. 1 May 2003

Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis.
Lietz, A. and Janz, M. and Sigvardsson, M. and Jundt, F. and Doerken, B. and Mathas, S.
British Journal of Haematology 137 (4): 342-348. May 2007

Differential Emu enhancer activity and expression of BOB.1/OBF.1, Oct2, PU.1, and immunoglobulin in reactive B-cell populations, B-cell non-Hodgkin lymphomas, and Hodgkin lymphomas.
Loddenkemper, C. and Anagnostopoulos, L. and Hummel, M. and Joehrens-Leder, K. and Foss, H.D. and Jundt, F. and Wirth, T. and Doerken, B. and Stein, H.
Journal of Pathology 202 (5): 60-69. 1 January 2004

Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19/anti-CD3 single-chain antibody construct.
Loeffler, A. and Gruen, M. and Wuchter, C. and Schriever, F. and Kufer, P. and Dreier, T. and Hanakam, F. and Baeuerle, P.A. and Bommert, K. and Karawajew, L. and Doerken, B. and Bargou, R.C.
Leukemia 17 (5): 900-909. May 2003

Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: Results of the German multicenter trials GMALL 03/87 and 04/89.
Ludwig, W.D. and Rieder, H. and Bartram, C.R. and Heinze, B. and Schwartz, S. and Gassmann, W. and Loeffler, H. and Hossfeld, D. and Heil, G. and Handt, S. and Heyll, A. and Diedrich, H. and Fischer, K. and Weiss, A. and Voelkers, B. and Aydemir, U. and Fonatsch, C. and Goekbuget, N. and Thiel, E. and Hoelzer, D.
Blood 92 (6): 1898-1909. 15 September 1998

A pilot study of prophylactic donor lymphocyte infusions to prevent relapse in adult acute lymphoblastic leukemias after allogeneic hematopoietic stem cell transplantation.
Lutz, C. and Massenkeil, G. and Nagy, M. and Neuburger, S. and Tamm, I. and Rosen, O. and Doerken, B. and Arnold, R.
Bone Marrow Transplantation 41 (9): 805-812. May 2008

APO-1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: correlation with bcl-2 oncogene expression.
Mapara, M.Y. and Bargou, R.C. and Zugck, C. . and Doehner, H. and Ustaoglu, F. and Jonker, R.R. and Krammer, P.H. and Doerken, B.
European Journal of Immunology 23 (3): 702-708. March 1993

Monitoring of tumor cell purging after highly efficient immunomagnetic selection of CD34 cells from leukapheresis products in breast cancer patients: comparision of immunocytochemical tumor cells staining and RT-PCR.
Mapara, M.Y. and Koerner, I.J. and Hildebrandt, M. and Bargou, R.C. and Krahl, D. and Reichardt, P. and Doerken, B.
Blood 89 (1): 337-344. 1 January 1997

Involvement of NAK-1, the human nur77 homologue, in surface IgM-mediated apoptosis in Burkitt lymphoma cell line BL41.
Mapara, M.Y. and Weinmann, P. and Bommert, K. and Daniel, P.T. and Bargou, R.C. and Doerken, B.
European Journal of Immunology 25 (9): 2506-2510. September 1995

G protein subunit G alpha16 expression is restricted to progenitor B-cells during human B-cell differentiation.
Mapara, M.Y. and Bommert, K. and Bargou, R.C. and Leng, C. and Beck, C. and Ludwig, W.D. and Gierschik, P. and Doerken, B.
Blood 85 (7): 1836-1842. 1 April 1995

Donor lymphocyte infusion-mediated graft-versus-leukemia effects in mixed chimeras established with a nonmyeloablative conditioning regimen: extinction of graft-versus-leukemia effects after conversion to full donor chimerism.
Mapara, M.Y. and Kim, Y.M. and Marx, J. and Sykes, M.
Transplantation 76 : 297-305. 27 July 2003

Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
Martin-Subero, J.I. and Wlodarska, I. and Bastard, C. and Picquenot, J.M. and Hoeppner, J. and Giefing, M. and Klapper, W. and Siebert, R. and Mathas, S. and Joos, S. and Stein, H. and Doerken, B.
Blood 108 : 401-403. 1 July 2006

Nonmyeloablative stem cell transplantation in patients with ALL and AML results in low nonrelapse mortality despite high rate of infections and GVHD.
Massenkeil, G. and Nagy, M. and Le Coutre, P. and Heine, F. and Rosen, O. and Doerken, B. and Arnold, R.
Hematology Journal 5 (5): 395-402. 1 January 2004

Survival after reduced-intensity conditioning is not inferior to standard high-dose conditioning before allogeneic haematopoietic cell transplantation in acute leukaemias.
Massenkeil, G. and Nagy, M. and Neuburger, S. and Tamm, I. and Lutz, C. and Le Coutre, P. and Rosen, O. and Wernecke, K.D. and Doerken, B. and Arnold, R.
Bone Marrow Transplantation 36 : 683-689. 22 August 2005

Nonmyeloablative stem cell transplantation in metastatic renal cell carcinoma: delayed graft-versus-tumor effect is associated with chimerism conversion but transplantation has high toxicity.
Massenkeil, G. and Roigas, J. and Nagy, M. and Wille, A. and Stroszczynski, C. and Mapara, M.Y. and Loening, S. and Doerken, B. and Arnold, R.
Bone Marrow Transplantation 34 (4): 309-316. 1 August 2004

Frequent induction of chromosomal aberrations in in vivo skin fibroblasts after allogeneic stem cell transplantation: hints to chromosomal instability after irradiation.
Massenkeil, G. and Zschieschang, P. and Thiel, G. and Hemmati, P.G. and Budach, V. and Doerken, B. and Pross, J. and Arnold, R.
Radiation Oncology 10 : 266. 30 December 2015

The pathogenesis of classical Hodgkin's lymphoma: a model for B-cell plasticity.
Mathas, S.
Hematology Oncology Clinics of North America 21 (5): 787-804. October 2007

Die molekulare Pathogenese des klassischen Hodgkin-Lymphoms [The molecular pathogenesis of classical Hodgkin lymphoma].
Mathas, S. and Doerken, B. and Janz, M.
Deutsche Medizinische Wochenschrift 134 (39): 1944-1948. September 2009

Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.
Mathas, S. and Hinz, M. and Anagnostopoulos, L. and Krappmann, D. and Lietz, A. and Jundt, F. and Bommert, K. and Mechta-Grigoriou, F. and Stein, H. and Doerken, B. and Scheidereit, C.
EMBO Journal 21 (15): 4104-4113. 1 August 2002

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.
Mathas, S. and Janz, M. and Hummel, F. and Hummel, M. and Wollert-Wulf, B. and Lusatis, S. and Anagnostopoulos, I. and Lietz, A. and Sigvardsson, M. and Jundt, F. and Joehrens, K. and Bommert, K. and Stein, H. and Doerken, B.
Nature Immunology 7 (2): 207-215. February 2006

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S. and Joehrens, K. and Joos, S. and Lietz, A. and Hummel, F. and Janz, M. and Jundt, F. and Anagnostopoulos, I. and Bommert, K. and Lichter, P. and Stein, H. and Scheidereit, C. and Doerken, B.
Blood 106 (13): 4287-4293. 25 August 2005

Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.
Mathas, S. and Kreher, S. and Meaburn, K.J. and Joehrens, K. and Lamprecht, B. and Assaf, C. and Sterry, W. and Kadin, M.E. and Daibata, M. and Joos, S. and Hummel, M. and Stein, H. and Janz, M. and Anagnostopoulos, I. and Schrock, E. and Misteli, T. and Doerken, B.
Proceedings of the National Academy of Sciences of the United States of America 106 (14): 5831-5836. 7 April 2009

c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas, S. and Lietz, A. and Anagnostopoulos, I. and Hummel, F. and Wiesner, B. and Janz, M. and Jundt, F. and Hirsch, B. and Joehrens-Leder, K. and Vornlocher, H.P. and Bommert, K. and Stein, H. and Doerken, B.
Journal of Experimental Medicine 199 (8): 1041-1052. 19 April 2004

Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis.
Mathas, S. and Lietz, A. and Janz, M. and Hinz, M. and Jundt, F. and Scheidereit, C. and Bommert, K. and Doerken, B.
Blood 102 (3): 1028-1034. 1 August 2003

The dangers of transcription.
Mathas, S. and Misteli, T.
Cell 139 (6): 1047-1049. 11 December 2009

Apoptosis-susceptibility prolongs the lack of memory B cells in acute leukemic patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A. and Oh, Y. and Becker, S.C. and Hemmati, P.G. and Jehn, C. and Westermann, J. and Szyska, M. and Göldner, H. and Dörken, B. and Scheibenbogen, C. and Arnold, R. and Na, I.K.
Biology of Blood and Marrow Transplantation 21 (11): 1895-1906. November 2015

Transformation and additional malignancies are leading risk factors for an adverse course of disease in marginal zone lymphoma.
Meyer, A.H. and Stroux, A. and Lerch, K. and Eucker, J. and Eitle, J. and Hohloch, K. and Andrzejak, M. and Possinger, K. and Dörken, B. and Pezzutto, A. and Scholz, C.W.
Annals of Oncology 25 (1): 210-215. January 2014

Eukaryotic initiation factor 2α phosphorylation is required for B cell maturation and function in mice.
Mielke, N. and Schwarzer, R. and Calkhoven, C.F. and Kaufman, R. and Doerken, B. and Leutz, A. and Jundt, F.
Haematologica 96 (9): 1261-1268. September 2011

Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M. and Fan, D.N.Y. and Belenki, D. and Däbritz, J.H.M. and Zhao, Z. and Yu, Y. and Dörr, J.R. and Dimitrova, L. and Lenze, D. and Monteiro Barbosa, I.A. and Mendoza-Parra, M.A. and Kanashova, T. and Metzner, M. and Pardon, K. and Reimann, M. and Trumpp, A. and Dörken, B. and Zuber, J. and Gronemeyer, H. and Hummel, M. and Dittmar, G. and Lee, S. and Schmitt, C.A.
Nature 553 (7686): 96-100. 4 January 2018

The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.
Mistry, A.C. and Mallick, R. and Froehlich, O. and Klein, J.D. and Rehm, A. and Chen, G. and Sands, J.M.
Journal of Biological Chemistry 282 (41): 30097-30106. 12 October 2007

Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma.
Mueller, A. and Zang, C. and Chumduri, C. and Doerken, B. and Daniel, P.T. and Scholz, C.W.
International Journal of Cancer 133 (8): 1813-1824. 15 October 2013

p14ARF-induced apoptosis in p53-deficient cells is mediated by the BH3-only protein independent de-repression of Bak through down-regulation of Mcl-1 and Bcl-xL.
Muer, A. and Overkamp, T. and Gillissen, B. and Richter, A. and Pretzsch, T. and Milojkovic, A. and Doerken, B. and Daniel, P.T. and Hemmati, P.
Journal of Biological Chemistry 287 (21): 17343-17352. 18 May 2012

Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Nagel, D. and Spranger, S. and Vincendeau, M. and Grau, M. and Raffegerst, S. and Kloo, B. and Hlahla, D. and Neuenschwander, M. and von Kries, J.P. and Hadian, K. and Doerken, B. and Lenz, P. and Lenz, G. and Schendel, D.J. and Krappmann, D.
Cancer Cell 22 (6): 825-837. 11 December 2012

Protein kinase C inhibitor Sotrastaurin selectively inhibits the growth of CD79-mutant diffuse large B-cell lymphomas.
Naylor, T.L. and Tang, H. and Ratsch, B.A. and Enns, A. and Loo, A. and Chen, L. and Lenz, P. and Schuler, W. and Doerken, B. and Yao, Y.M. and Warmuth, M. and Lenz, G. and Stegmeier, F.
Cancer Research 71 (7): 2643-2653. 1 April 2011

Successful salvage treatment of disseminated cutaneous fusariosis with liposomal amphotericin B and terbinafine after allogeneic stem cell transplantation.
Neuburger, S. and Massenkeil, G. and Seibold, M. and Lutz, C. and TammI, I. and Le Coutre, P. and Graf, B. and Doerken, B. and Arnold, R.
Transplant Infectious Disease 10 (4): 290-293. August 2008

BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features.
Neuendorff, N.R. and Burmeister, T. and Doerken, B. and Westermann, J.
Annals of Hematology 95 (8): 1211-1221. August 2016

BCR-ABL1 acute myeloid leukemia: clonal selection of a BCR-ABL1(-) subclone as a cause of refractory disease with nilotinib treatment.
Neuendorff, N.R. and Schwarz, M. and Hemmati, P. and Tuerkmen, S. and Bommer, C. and Burmeister, T. and Doerken, B. and le Coutre, P. and Arnold, R. and Westermann, J.
Acta Haematologica 133 (2): 237-241. 2015

HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: gene gun is superior to jet injector in inducing CTL responses and protective immunity.
Nguyen-Hoai, T. and Kobelt, D. and Hohn, O. and Vu, M.D. and Schlag, P.M. and Doerken, B. and Norley, S. and Lipp, M. and Walther, W. and Pezzutto, A. and Westermann, J.
OncoImmunology 1 (9): 1537-1545. 1 December 2012

CCL4 as an adjuvant for DNA vaccination in a Her2/neu mouse tumor model.
Nguyen-Hoai, T. and Pham-Duc, M. and Gries, M. and Dörken, B. and Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 23 (6): 162-167. June 2016

Initial chemotherapy with mitoxantrone, chlorambucil, prednisone impairs the collection of stem cells in patients with indolent lymphomas--results of a randomized comparison by the German Low-Grade Lymphoma Study Group.
Nickenig, C. and Dreyling, M. and Hoster, E. and Ludwig, W.D. and Doerken, B. and Freund, M. and Huber, C. and Ganser, A. and Truemper, L. and Forstpointner, R. and Unterhalt, M. and Hiddemann, W.
Annals of Oncology 18 (1): 136-142. January 2007

Pathogenesis of non-Hodgkin's lymphoma.
Nogai, H. and Doerken, B. and Lenz, G.
Journal of Clinical Oncology 29 (14): 1803-1811. 10 May 2011

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H. and Wenzel, S.S. and Hailfinger, S. and Grau, M. and Kaergel, E. and Seitz, V. and Wollert-Wulf, B. and Pfeifer, M. and Wolf, A. and Frick, M. and Dietze, K. and Madle, H. and Tzankov, A. and Hummel, M. and Dörken, B. and Scheidereit, C. and Janz, M. and Lenz, P. and Thome, M. and Lenz, G.
Blood 122 (13): 2242-2250. 26 September 2013

Clinical lessons to be learned from patients developing chronic myeloid leukemia while on immunosuppressive therapy after solid organ transplantation: yet another dase after orthotopic heart transplantation.
Oberender, C. and Kleeberg, L. and Nienhues, N. and Gresse, M. and Doerken, B. and Riess, H. and le Coutre, P.
Case Reports in Hematology 2014 : 890438. 16 November 2014

Morphologic diagnosis of leukaemic B-lymphoproliferative disorders and the role of cyclin D1 expression.
Oertel, J. and Kingreen, D. and Busemann, C. and Stein, H. and Doerken, B.
Journal of Cancer Research and Clinical Oncology 128 (4): 182-188. April 2002

Epstein-Barr viral load in whole blood of adults with posttransplant lymphoproliferative disorder after solid organ transplantation does not correlate with clinical course.
Oertel, S. and Trappe, R.U. and Zeidler, K. and Babel, N. and Reinke, P. and Hummel, M. and Jonas, S. and Papp-Vary, M. and Subklewe, M. and Doerken, B. and Riess, H. and Gaertner, B.
Annals of Hematology 85 : 478-484. July 2006

Effect of anti-CD 20 antibody rituximab in patients with post-transplant lymphoproliferative disorder (PTLD).
Oertel, S.H. and Verschuuren, E. and Reinke, P. and Zeidler, K. and Papp-Vary, M. and Babel, N. and Trappe, R.U. and Jonas, S. and Hummel, M. and Anagnostopoulos, I. and Doerken, B. and Riess, H.B.
American Journal of Transplantation 5 : 2901-2906. 1 December 2005

Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial.
Oettle, H. and Post, S. and Neuhaus, P. and Gellert, K. and Langrehr, J. and Ridwelski, K. and Schramm, H. and Fahlke, J. and Zuelke, C. and Burkart, C. and Gutberlet, K. and Kettner, E. and Schmalenberg, H. and Weigang-Koehler, K. and Bechstein, W.O. and Niedergethmann, M. and Schmidt-Wolf, I. and Roll, L. and Doerken, B. and Riess, H.
JAMA: Journal of the American Medical Association 297 (3): 267-277. 17 January 2007

Second-line oxaliplatin, folinic acid, and fluorouracil versus folinic acid and fluorouracil alone for gemcitabine-refractory pancreatic cancer : outcomes from the CONKO-003 trial.
Oettle, H. and Riess, H. and Stieler, J.M. and Heil, G. and Schwaner, I. and Seraphin, J. and Goerner, M. and Moelle, M. and Greten, T.F. and Lakner, V. and Bischoff, S. and Sinn, M. and Doerken, B. and Pelzer, U.
Journal of Clinical Oncology 32 (23): 2423-2429. 10 August 2014

C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells.
Pal, R. and Janz, M. and Galson, D.L. and Gries, M. and Li, S. and Johrens, K. and Anagnostopoulos, I. and Doerken, B. and Mapara, M.Y. and Borghesi, L. and Kardava, L. and Roodman, G.D. and Milcarek, C. and Lentzsch, S.
Blood 114 (18): 3890-3898. 29 October 2009

Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro.
Panzenboeck, B. and Bartunek, P. and Mapara, M.Y. and Zenke, M.
Blood 92 (10): 3658-3668. 15 November 1998

Assessment of genomic instability in breast cancer and uveal melanoma by random amplified polymorphic DNA analysis.
Papadopoulos, S. and Benter, T. and Anastassiou, G. and Pape, M. and Gerhard, S. and Bornfeld, N. and Ludwig, W.D. and Doerken, B.
International Journal of Cancer 99 (2): 193-200. 10 May 2002

Induction of cellular immunity in chimpanzees to human tumor associated antigen mucin by vaccination with MUC-1 cDNA-transfected Epstein-Barr virus-immortalized autologous B cells.
Pecher, G. and Finn, O.J.
Proceedings of the National Academy of Sciences of the United States of America 93 (4): 1699-1704. 20 February 1996

Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study.
Pelzer, U. and Arnold, D. and Govercin, M. and Stieler, J. and Doerken, B. and Riess, H. and Oettle, H.
BMC Cancer 10 (1): 86. 9 March 2010

First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group.
Pelzer, U. and Arnold, D. and Reitzig, P. and Herrenberger, J. and Korsten, F.W. and Kindler, M. and Stieler, J. and Doerken, B. and Riess, H. and Oettle, H.
Cancer Chemotherapy and Pharmacology 68 (5): 1173-1178. November 2011

Value of carbohydrate antigen 19-9 in predicting response and therapy control in patients with metastatic pancreatic cancer undergoing first-line therapy.
Pelzer, U. and Hilbig, A. and Sinn, M. and Stieler, J. and Bahra, M. and Doerken, B. and Riess, H.
Frontiers in Oncology 3 : 155. June 2013

Intensified chemotherapy and simultaneous treatment with heparin in outpatients with pancreatic cancer - the CONKO 004 pilot trial.
Pelzer, U. and Hilbig, A. and Stieler, J.M. and Bahra, M. and Sinn, M. and Gebauer, B. and Doerken, B. and Riess, H.
BMC Cancer 14 (1): 204. 19 March 2014

Blood group determinates incidence for pancreatic cancer in Germany.
Pelzer, U. and Klein, F. and Bahra, M. and Sinn, M. and Doerken, B. and Neuhaus, P. and Meyer, O. and Riess, H.
Frontiers in Physiology 4 : 118. 24 May 2013

Efficacy of prophylactic low-molecular weight heparin for ambulatory patients with advanced pancreatic cancer: outcomes from the CONKO-004 trial.
Pelzer, U. and Opitz, B. and Deutschinoff, G. and Stauch, M. and Reitzig, P.C. and Hahnfeld, S. and Mueller, L. and Grunewald, M. and Stieler, J.M. and Sinn, M. and Denecke, T. and Bischoff, S. and Oettle, H. and Doerken, B. and Riess, H.
Journal of Clinical Oncology 33 (18): 2028-2034. 20 June 2015

Best supportive care (BSC) versus oxaliplatin, folinic acid and 5-fluorouracil (OFF) plus BSC in patients for second-line advanced pancreatic cancer: A phase III-study from the German CONKO-study group.
Pelzer, U. and Schwaner, I. and Stieler, J. and Adler, M. and Seraphin, J. and Doerken, B. and Riess, H. and Oettle, H.
European Journal of Cancer 47 (11): 1676-1681. July 2011

Second-line therapy in refractory pancreatic cancer. results of a phase II study.
Pelzer, U. and Stieler, J. and Roll, L. and Hilbig, A. and Doerken, B. and Riess, H. and Oettle, H.
Onkologie 32 (3): 99-102. March 2009

Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes.
Pfeifer, M. and Zheng, B. and Erdmann, T. and Koeppen, H. and McCord, R. and Grau, M. and Staiger, A. and Chai, A. and Sandmann, T. and Madle, H. and Doerken, B. and Chu, Y.W. and Chen, A.I. and Lebovic, D. and Salles, G.A. and Czuczman, M.S. and Palanca-Wessels, M.C. and Press, O.W. and Advani, R. and Morschhauser, F. and Cheson, B.D. and Lenz, P. and Ott, G. and Polson, A.G. and Mundt, K.E. and Lenz, G.
Leukemia 29 (7): 1578-1586. July 2015

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer, M. and Grau, M. and Lenze, D. and Wenzel, S.S. and Wolf, A. and Wollert-Wulf, B. and Dietze, K. and Nogai, H. and Storek, B. and Madle, H. and Dörken, B. and Janz, M. and Dirnhofer, S. and Lenz, P. and Hummel, M. and Tzankov, A. and Lenz, G.
Proceedings of the National Academy of Sciences of the United States of America 110 (30): 12420-12425. 23 July 2013

Harm or benefit of hormonal treatment in metastatic low-grade endometrial stromal sarcoma: Single center experience with 10 cases and review of the literature.
Pink, D. and Lindner, T. and Mrozek, A. and Kretzschmar, A. and Thuss-Patience, P.C. and Doerken, B. and Reichardt, P.
Gynecologic Oncology 101 : 464-469. June 2006

Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma.
Rahal, R. and Frick, M. and Romero, R. and Korn, J.M. and Kridel, R. and Chun Chan, F. and Meissner, B. and Bhang, H.E. and Ruddy, D. and Kauffmann, A. and Farsidjani, A. and Derti, A. and Rakiec, D. and Naylor, T. and Pfister, E. and Kovats, S. and Kim, S. and Dietze, K. and Doerken, B. and Steidl, C. and Tzankov, A. and Hummel, M. and Monahan, J. and Morrissey, M.P. and Fritsch, C. and Sellers, W.R. and Cooke, V.G. and Gascoyne, R.D. and Lenz, G. and Stegmeier, F.
Nature Medicine 20 (1): 87-92. January 2014

Common clonal origin of an acute B lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity.
Ratei, R. and Hummel, M. and Anagnostopoulos, I. and Jaehne, D. and Arnold, R. and Doerken, B. and Mathas, S. and Thomas, B. and Dudeck, O. and Ludwig, W.D. and Stein, H.
Haematologica 95 (9): 1461-1466. September 2010

Salvage therapy for relapsed mediastinal B-cell lymphoma with allogeneic HLA-identical related donor bone marrow transplantation, donor lymphocyte infusion and IDEC-C2B8.
Ratei, R. and Matylis, A. and Krahl, D. and Arnold, R. and Stein, H. and Doerken, B. and Ludwig, W.D.
Leukemia & Lymphoma 40 (1-2): 133-140. December 2000

The use of microarray technologies in mantle cell lymphoma.
Ratsch, B.A. and Grau, M. and Doerken, B. and Lenz, P. and Lenz, G.
Seminars in Hematology 48 (3): 166-171. July 2011

Dynamic expression profile of p21 WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy.
Rau, B. and Sturm, I. and Lage, H. and Berger, S. and Schneider, U. and Haupfmann, S. and Wust, P. and Riess, H. and Schlag, P.M. and Doerken, B. and Daniel, P.T.
Journal of Clinical Oncology 21 (18): 3391-3401. 15 September 2003

Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma.
Rehm, A. and Anagnostopoulos, I. and Gerlach, K. and Broemer, M. and Scheidereit, C. and Joehrens, K. and Huebler, M. and Hetzer, R. and Stein, H. and Lipp, M. and Doerken, B. and Hoepken, U.E.
International Journal of Cancer 125 (10): 2367-2374. 15 November 2009

Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Rehm, A. and Mensen, A. and Schradi, K. and Gerlach, K. and Wittstock, S. and Winter, S. and Buechner, G. and Doerken, B. and Lipp, M. and Hoepken, U.E.
Blood 118 (4): 1020-1033. 28 July 2011

Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A. and Gätjen, M. and Gerlach, K. and Scholz, F. and Mensen, A. and Gloger, M. and Heinig, K. and Lamprecht, B. and Mathas, S. and Bégay, V. and Leutz, A. and Lipp, M. and Dörken, B. and Höpken, U.E.
Nature Communications 5 : 5057. 30 September 2014

Empirical antimicrobial monotherapy in patients after high-dose chemotherapy and autologous stem cell transplantation: a randomised, multicentre trial.
Reich, G. and Cornely, O.A. and Sandherr, M. and Kubin, T. and Krause, S. and Einsele, H. and Thiel, E. and Bellaire, T. and Doerken, B. and Maschmeyer, G.
British Journal of Haematology 130 : 265-270. 1 July 2005

An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma.
Reichardt, P. and Oechsle, K. and Pink, D. and Bokemeyer, C. and Schneller, F. and Issels, R. and Kanz, L. and Hartmann, J.T.
Investigational New Drugs 21 : 481-486. 1 November 2003

Dose-intensive chemotherapy with ifosfamide, epirubicin, and filgrastim for adult patients with metastatic or locally advanced soft tissue sarcoma: A phase II study.
Reichardt, P. and Tilgner, J. and Hohenberger, P. and Doerken, B.
Journal of Clinical Oncology 16 (4): 1438-1443. April 1998

Chemotherapy in alveolar soft part sarcomas: What do we know?
Reichardt, P. and Lindner, T. and Pink, D. and Thuss-Patience, P.C. and Kretzschmar, A. and Doerken, B.
European Journal of Cancer 39 (11): 1511-1516. 1 July 2003

Identification and quantification of in vitro adduct formation between protein reactive xenobiotics and a lysine-containing model peptide.
Reichardt, P. and Schreiber, A. and Wichmann, G. and Metzner, G. and Efer, J. and Raabe, F.
Environmental Toxicology 18 : 29-36. 1 February 2003

Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Reimann, M. and Lee, S. and Loddenkemper, C. and Doerr, J.R. and Tabor, V. and Aichele, P. and Stein, H. and Doerken, B. and Jenuwein, T. and Schmitt, C.A.
Cancer Cell 17 (3): 262-272. 16 March 2010

The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Reimann, M. and Loddenkemper, C. and Rudolph, C. and Schildhauer, I. and Teichmann, B. and Stein, H. and Schlegelberger, B. and Doerken, B. and Schmitt, C.A.
Blood 110 (8): 2996-3004. 15 October 2007

Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker.
Reimer, T.A. and Anagnostopoulos, I. and Erdmann, B. and Lehmann, I. and Stein, H. and Daniel, P. and Doerken, B. and Rehm, A.
BMC Cancer 5 (1): 47. 1 January 2005

Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86.
Reiter, A. and Schrappe, M. and Ludwig, W.D. and Hiddemann, W. and Sauter, S. and Henze, G. and Zimmermann, M. and Lampert, F. and Havers, W. and Niethammer, D. and Odenwald, E. and Ritter, J. and Mann, G. and Welte, K. and Gadner, H. and Riehm, H.
Blood 84 (9): 3122-3133. 1 November 1994

Identifikation molekularer Regulatoren der anti-IgM induzierten B-Zell Apoptose.
Rickers, A.
UNSPECIFIED thesis, UNSPECIFIED. 16 February 1999

Rationale and design of PROSPECT-CONKO 004: a prospective, randomized trial of simultaneous pancreatic cancer treatment with enoxaparin and chemotherapy.
Riess, H. and Pelzer, U. and Hilbig, A. and Stieler, J. and Opitz, B. and Scholten, T. and Kauschat-Bruning, D. and Bramlage, P. and Doerken, B. and Oettle, H.
BMC Cancer 8 (1): 361. 5 December 2008

Effects of Jak2 type 1 inhibitors NVP-BSK805 and NVP-BVB808 on Jak2 mutation-positive and Bcr-Abl-positive cell lines.
Ringel, F. and Kaeda, J. and Schwarz, M. and Oberender, C. and Grille, P. and Doerken, B. and Marque, F. and Manley, P.W. and Radimerski, T. and le Coutre, P.
Acta Haematologica 132 (1): 75-86. 31 January 2014

The origins of ALK translocations.
Roukos, V. and Mathas, S.
Frontiers in Bioscience 7 : 260-268. 1 June 2015

The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.
Rueder, C. and Hoepken, U.E. and Wolf, J. and Mittruecker, H.W. and Engels, B. and Erdmann, B. and Wollenzin, S. and Uckert, W. and Doerken, B. and Rehm, A.
Journal of Clinical Investigation 119 (8): 2184-2203. August 2009

EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with Snapin.
Rueder, C. and Reimer, T. and Delgado-Martinez, I. and Hermosilla, R. and Engelsberg, A. and Nehring, R. and Doerken, B. and Rehm, A.
Molecular Biology of the Cell 16 (3): 1245-1257. 5 January 2005

Stroma-mediated dysregulation of myelopoiesis in mice lacking IkappaBalpha.
Rupec, R.A. and Jundt, F. and Rebholz, B. and Eckelt, B. and Weindl, G.N. and Herzinger, T. and Flaig, M.J. and Moosmann, S. and Plewig, G. and Doerken, B. and Foerster, I. and Huss, R. and Pfeffer, K.
Immunity 22 : 479-491. 1 January 2005

The prognostic significance of antigen expression in leukaemia.
Schabath, R. and Ratei, R. and Ludwig, W.D.
Best Practice & Research in Clinical Haematology 16 : 613-628. 1 December 2003

T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct.
Schlereth, B. and Quadt, C. and Dreier, T. and Kufer, P. and Lorenczewski, G. and Prang, N. and Brandl, C. and Lippold, S. and Cobb, K. and Brasky, K. and Leo, E. and Bargou, R. and Murthy, K. and Baeuerle, P.A.
Cancer Immunology Immunotherapy 55 : 503-514. May 2006

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Schleussner, N. and Merkel, O. and Costanza, M. and Liang, H.C. and Hummel, F. and Romagnani, C. and Durek, P. and Anagnostopoulos, I. and Hummel, M. and Jöhrens, K. and Niedobitek, A. and Griffin, P.R. and Piva, R. and Sczakiel, H.L. and Woessmann, W. and Damm-Welk, C. and Hinze, C. and Stoiber, D. and Gillissen, B. and Turner, S.D. and Kaergel, E. and von Hoff, L. and Grau, M. and Lenz, G. and Dörken, B. and Scheidereit, C. and Kenner, L. and Janz, M. and Mathas, S.
Leukemia 32 (9): 1994-2007. September 2018

Induction of gene expression by 5-Aza-2'-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and -independent mechanisms.
Schmelz, K. and Sattler, N. and Wagner, M. and Luebbert, M. and Doerken, B. and Tamm, I.
Leukemia 19 : 103-111. 1 January 2005

5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.
Schmelz, K. and Wagner, M. and Doerken, B. and Tamm, I.
International Journal of Cancer 114 : 683-695. 1 May 2005

Detection of circulating tumor-associated antigen depends on the domains recognized by the monoclonal antibodies used: N-terminal trimmed EpCAM-levels are much higher than untrimmed forms.
Schmetzer, O. and Moldenhauer, G. and Nicolaou, A. and Schlag, P. and Riesenberg, R. and Pezzutto, A.
Immunology Letters 143 (2): 184-192. 30 April 2012

Use of Kaede fusions to visualize recycling of G protein-coupled receptors.
Schmidt, A. and Wiesner, B. and Weisshart, K. and Schulz, K. and Furkert, J. and Lamprecht, B. and Rosenthal, W. and Schuelein, R.
Traffic 10 (1): 2-15. January 2009

Four versus six courses of a dose-escalated cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) regimen plus etoposide (megaCHOEP) and autologous stem cell transplantation.
Schmitz, N. and Kloess, M. and Reiser, M. and Berdel, W.E. and Metzner, B. and Doerken, B. and Kneba, M. and Trumper, L. and Loeffler, M. and Pfreundschuh, M. and Glass, B.
Cancer 106 : 136-145. 1 January 2006

Identifikation Apoptose-assoziierter Gene in B-Zellen und Charakterisierung des Genproduktes LAPTM5.
Schneider, H.
UNSPECIFIED thesis, UNSPECIFIED. 16 January 2003

Flow cytometric maturity score as a novel prognostic parameter in patients with acute myeloid leukemia.
Schneider, T. and Flörcken, A. and Singh, A. and Türkmen, S. and Burmeister, T. and Anagnostopoulos, I. and Pezzutto, A. and Dörken, B. and Westermann, J.
Annals of Hematology 94 (8): 1337-1345. August 2015

Activation of human T cell lymphotropic virus type I-infected T cells is independent of B7 costimulation.
Scholz, C. and Freeman, G.J. and Greenfield, E.A. and Hafler, D.A. and Hollsberg, P.
Journal of Immunology 157 (7): 2932-2938. 1 October 1996

Distinction of acute lymphoblastic leukemia from acute myeloid leukemia through microarray-based DNA methylation analysis.
Scholz, C. and Nimmrich, I. and Burger, M. and Becker, E. and Doerken, B. and Ludwig, W.D. and Maier, S.
Annals of Hematology 84 : 236-244. 1 January 2005

Characterization of apoptosis-induced Mcm3 and Cdc6 cleavage reveals a proapoptotic effect for one Mcm3 fragment.
Schories, B. and Engel, K. and Doerken, B. and Gossen, M. and Bommert, K.
Cell Death and Differentiation 11 (8): 940-942. August 2004

Downregulation of genes involved in DNA repair and differential expression of transcription regulators and phosphatases precede IgM-induced apoptosis in the Burkitt's lymphoma cell line BL60-2.
Schories, B. and Janz, M. and Doerken, B. and Bommert, K.
Biochimica et Biophysica Acta - Gene Structure and Expression 1676 (1): 83-95. 1 January 2004

Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells.
Schwarzer, R. and Doerken, B. and Jundt, F.
Leukemia 26 (4): 806-813. April 2012

Notch and NF-κB signaling pathways in the biology of classical Hodgkin lymphoma.
Schwarzer, R. and Jundt, F.
Current Molecular Medicine 11 (3): 236-245. April 2011

Notch inhibition blocks multiple myeloma cell-induced osteoclast activation.
Schwarzer, R. and Kaiser, M. and Acikgoez, O. and Heider, U. and Mathas, S. and Preissner, R. and Sezer, O. and Doerken, B. and Jundt, F.
Leukemia 22 (12): 2273-2277. December 2008

Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model.
Schwarzer, R. and Nickel, N. and Godau, J. and Willie, B.M. and Duda, G.N. and Schwarzer, R. and Cirovic, B. and Leutz, A. and Manz, R. and Bogen, B. and Dörken, B. and Jundt, F.
Blood Cancer Journal 4 : e217. 13 June 2014

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel, D. and Arasu, B.S. and Marino, S.F. and Lamprecht, B. and Köchert, K. and Rosenbaum, E. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Rocks, O. and Mathas, S. and Daumke, O.
Structure 21 (4): 550-559. 2 April 2013

Peripheral blood sCD3(-) CD4(+) T cells: a useful diagnostic tool in angioimmunoblastic T cell lymphoma.
Singh, A. and Schabath, R. and Ratei, R. and Stroux, A. and Klemke, C.D. and Nebe, T. and Flörcken, A. and van Lessen, A. and Anagnostopoulos, I. and Dörken, B. and Ludwig, W.D. and Pezzutto, A. and Westermann, J.
Hematological Oncology 32 (1): 16-21. March 2014

Second-line treatment in pancreatic cancer patients: Who profits? Results from the CONKO study group.
Sinn, M. and Daelken, L. and Striefler, J.K. and Bischoff, S. and Schweitzer, N. and Pelzer, U. and Doerken, B. and Riess, H. and Stieler, J.M.
Pancreas 45 (4): 601-605. April 2016

α-smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study.
Sinn, M. and Denkert, C. and Striefler, J.K. and Pelzer, U. and Stieler, J.M. and Bahra, M. and Lohneis, P. and Doerken, B. and Oettle, H. and Riess, H. and Sinn, B.V.
British Journal of Cancer 111 (10): 1917-1923. 11 November 2014

Hepatic arterial infusion with oxaliplatin and 5-FU/folinic acid for advanced biliary tract cancer: a phase II study.
Sinn, M. and Nicolaou, A. and Gebauer, B. and Podrabsky, P. and Seehofer, D. and Ricke, J. and Doerken, B. and Riess, H. and Hildebrandt, B.
Digestive Diseases and Sciences 58 (8): 2399-2405. August 2013

Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with primary liver cancer: a phase II-study (NCT00356161).
Sinn, M. and Nicolaou, A. and Ricke, J. and Podrabsky, P. and Seehofer, D. and Gebauer, B. and Pech, M. and Neuhaus, P. and Doerken, B. and Riess, H. and Hildebrandt, B.
BMC Gastroenterology 13 : 125. 9 August 2013

SPARC expression in resected pancreatic cancer patients treated with Gemcitabine: results from the CONKO-001 study.
Sinn, M. and Sinn, B.V. and Striefler, J.K. and Lindner, J.L. and Stieler, J.M. and Lohneis, P. and Bischoff, S. and Blaeker, H. and Pelzer, U. and Neuhaus, P. and Dietel, M. and Doerken, B. and Oettle, H. and Riess, H. and Denkert, C.
Annals of Oncology 25 (5): 1025-1032. May 2014

Does long-term survival in patients with pancreatic cancer really exist? Results from the CONKO-001 study.
Sinn, M. and Striefler, J.K. and Sinn, B.V. and Sallmon, D. and Bischoff, S. and Stieler, J.M. and Pelzer, U. and Bahra, M. and Neuhaus, P. and Doerken, B. and Denkert, C. and Riess, H. and Oettle, H.
Journal of Surgical Oncology 108 (6): 398-402. November 2013

Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A. and Moebs, M. and Ullmann, R. and Koechert, K. and Kreher, S. and Lamprecht, B. and Anagnostopoulos, I. and Hummel, M. and Richter, J. and Beyer, M. and Janz, M. and Klemke, C.D. and Stein, H. and Doerken, B. and Sterry, W. and Schrock, E. and Mathas, S. and Assaf, C.
Journal of Experimental Medicine 208 (8): 1585-1593. 1 August 2011

Polymerase chain reaction monitoring shows a high efficacy of clinical immunomagnetic purging in patients with centroblastic- centrocytic non-Hodgkin's lymphoma.
Straka, C. and Kroner, C. and Doerken, B. and Kvalheim, G.
Blood 80 (10): 2688-2690. 15 November 1992

Selective pharmacologic activation of the p53-dependent pathway as a therapeutic strategy for hematologic malignancies.
Stuehmer, T. and Bargou, R.C.
Cell Cycle 5 : 39-42. 1 January 2006

Non-genotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.
Stuehmer, T. and Chatterjee, M. and Hildebrandt, M. and Herrmann, P. and Gollasch, H. and Gerecke, C. and Theurich, S. and Cigliano, L. and Manz, R.A. and Daniel, P.T. and Bommert, K. and Vassilev, L.T. and Bargou, R.C.
Blood 106 : 3609-3617. 4 August 2005

In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis.
Sturm, I. and Bosanquet, A.G. and Hummel, M. and Doerken, B. and Daniel, P.T.
BMC Cancer 5 : 105. 18 August 2005

Panhypopituitarism in a patient with breast cancer.
Sturm, I. and Kirschke, S. and Krahl, D. and Doerken, B.
Onkologie 27 : 480-482. 1 January 2004

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Sturm, I. and Stephan, C. and Gillissen, B. and Siebert, R. and Janz, M. and Radetzki, S. and Jung, K. and Loening, S. and Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 13 : 619-627. April 2006

Dendritic cell maturation stage determines susceptibility to the proteasome inhibitor bortezomib.
Subklewe, M. and Sebelin-Wulf, K. and Beier, C. and Lietz, A. and Mathas, S. and Doerken, B. and Pezzutto, A.
Human Immunology 68 (3): 147-155. March 2007

A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo.
Szyska, M. and Herda, S. and Althoff, S. and Heimann, A. and Russ, J. and D'Abundo, D. and Dang, T.M. and Durieux, I. and Dörken, B. and Blankenstein, T. and Na, I.K.
Cancer Immunology Research 6 (1): 110-120. January 2018

CT-gesteuerte bronchoskopische Punktion zur Diagnosesicherung einer hilaeren Raumforderung [CT-controlled bronchoscopic puncture in diagnostic verification of hilar space occupying lesion].
Teichgraeber, U.K. and Gebauer, B. and Benter, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 175 : 857-858. 1 June 2003

Central venous access catheters: radiological management of complications.
Teichgraeber, U.K. and Gebauer, B. and Benter, T. and Wagner, H.J.
Cardiovascular and Interventional Radiology 26 : 321-333. 1 July 2003

A modified EBMT risk score and the hematopoietic cell transplantation-specific comorbidity index for pre-transplant risk assessment in adult acute lymphoblastic leukemia.
Terwey, T.H. and Hemmati, P.G. and Martus, P. and Dietz, E. and Vuong, L.G. and Massenkeil, G. and Doerken, B. and Arnold, R.
Haematologica 95 (5): 810-818. May 2010

Comparison of chimerism and minimal residual disease monitoring for relapse prediction after allogeneic stem cell transplantation for adult acute lymphoblastic leukemia.
Terwey, T.H. and Hemmati, P.G. and Nagy, M. and Pfeifer, H. and Goekbuget, N. and Brueggemann, M. and Le Duc, T.M. and le Coutre, P. and Doerken, B. and Arnold, R.
Biology of Blood and Marrow Transplantation 20 (10): 1522-1529. October 2014

NIH-defined graft-versus-host disease and evidence for a potent graft-versus-leukemia effect in patients with acute lymphoblastic leukemia.
Terwey, T.H. and Le Duc, T.M. and Hemmati, P.G. and le Coutre, P. and Nagy, M. and Martus, P. and Doerken, B. and Arnold, R.
Annals of Oncology 24 (5): 1363-1370. May 2013

Allogeneic SCT in refractory or relapsed adult ALL is effective without prior reinduction chemotherapy.
Terwey, T.H. and Massenkeil, G. and Tamm, I. and Hemmati, P.G. and Neuburger, S. and Martus, P. and Doerken, B. and Hoelzer, D. and Arnold, R.
Bone Marrow Transplantation 42 (12): 791-798. December 2008

NIH-defined graft-versus-host disease after reduced intensity or myeloablative conditioning in patients with acute myeloid leukemia.
Terwey, T.H. and Vega-Ruiz, A. and Hemmati, P.G. and Martus, P. and Dietz, E. and le Coutre, P. and Massenkeil, G. and Doerken, B. and Arnold, R.
Leukemia 26 (3): 536-542. March 2012

Untersuchungen zur Molekularpathologie des Hodgkin-Lymphoms - Klonierung des I kappa B epsilon Gens und Mutationsanalyse in Einzelzellen.
Theurich, S.
UNSPECIFIED thesis, UNSPECIFIED. 24 July 2006

Recurrent gastric adenocarcinoma with unusual metastatic localization and excellent response to docetaxel and 5-FU continuous infusion.
Thuss-Patience, P.C. and Kretzschmar, A. and Krenn, V. and Doerken, B. and Reichardt, P.
Onkologie 26 (1): 63-65. 1 February 2003

Docetaxel and continuous-infusion fluorouracil versus epirubicin, cisplatin, and fluorouracil for advanced gastric adenocarcinoma: a randomized phase II study.
Thuss-Patience, P.C. and Kretzschmar, A. and Repp, M. and Kingreen, D. and Hennesser, D. and Micheel, S. and Pink, D. and Scholz, C. and Doerken, B. and Reichardt, P.
Journal of Clinical Oncology 23 : 494-501. 1 January 2005

Acute hypokalemic tetraparesis induced by intravenous methotrexate.
Thuss-Patience, P.C. and Peters, U. and Jurkat-Rott, K. and Pink, D. and Kretzschmar, A. and Doerken, B. and Reichardt, P.
Journal of Clinical Oncology 21 (9): 1896-1897. 1 May 2003

Oxaliplatin and 5-fluorouracil for heavily pretreated metastatic breast cancer: a preliminary phase II study.
Thuss-Patience, P.C. and von Minckwitz, G. and Kretzschmar, A. and Loibl, S. and Schaller, G. and Doerken, B. and Reichardt, P.
Anti-Cancer Drugs 14 (7): 549-553. 1 August 2003

Treatment of PTLD with rituximab and CHOP reduces the risk of renal graft impairment after reduction of immunosuppression.
Trappe, R. and Hinrichs, C. and Appel, U. and Babel, N. and Reinke, P. and Neumayer, H.H. and Budde, K. and Dreyling, M. and Duehrsen, U. and Kliem, V. and Schuettrumpf, S. and Hauser, I.A. and Mergenthaler, H.G. and Schlattmann, P. and Anagnostopoulos, I. and Doerken, B. and Riess, H.
American Journal of Transplantation 9 (10): 2331-2337. October 2009

Successful treatment of thrombocytopenia in primary antiphospholipid antibody syndrome with the anti-CD20 antibody rituximab-monitoring of antiphospholipid and anti-GP antibodies: a case report.
Trappe, R. and Loew, A. and Thuss-Patience, P. and Doerken, B. and Riess, H.
Annals of Hematology 85 : 134-135. February 2006

Salvage chemotherapy for refractory and relapsed posttransplant lymphoproliferative disorders (PTLD) after treatment with single-agent rituximab.
Trappe, R. and Riess, H. and Babel, N. and Hummel, M. and Lehmkuhl, H. and Jonas, S. and Anagnostopoulos, I. and Papp-Vary, M. and Reinke, P. and Hetzer, R. and Doerken, B. and Oertel, S.
Transplantation 83 (7): 912-918. 15 April 2007

Salvage therapy for relapsed posttransplant lymphoproliferative disorders (PTLD) with a second progression of PTLD after upfront chemotherapy: the role of single-agent rituximab.
Trappe, R.U. and Choquet, S. and Reinke, P. and Dreyling, M. and Mergenthaler, H.G. and Jaeger, U. and Kebelmann-Betzing, C. and Jonas, S. and Lehmkuhl, H. and Anagnostopoulos, I. and Leblond, V. and Hetzer, R. and Doerken, B. and Riess, H. and Oertel, S.
Transplantation 84 (12): 1708-1712. 27 December 2007

Effective use of high-dose chemotherapy and autologous stem cell rescue for relapsed adult Wilms' tumor and a novel alteration in intron 1 of the WT1 gene.
Trappe, R.U. and Riess, H. and Lippek, F. and Plotkin, M. and Schumacher, V. and Royer-Pokora, B. and Hildebrandt, B. and Zuber, J. and Mapara, M.Y. and Oertel, S. and Doerken, B.
Journal of Pediatric Hematology Oncology 26 : 820-823. 1 January 2004

High prevalence of immunoglobulin light chain gene aberrations as revealed by FISH in multiple myeloma and MGUS.
Tuerkmen, S. and Binder, A. and Gerlach, A. and Niehage, S. and Melissari, M.T. and Inandiklioglu, N. and Doerken, B. and Burmeister, T.
Genes Chromosomes & Cancer 53 (8): 650-656. August 2014

The IL-15 cytokine system provides growth and survival signals in hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells.
Ullrich, K. and Blumenthal-Barby, F. and Lamprecht, B. and Koechert, K. and Lenze, D. and Hummel, M. and Mathas, S. and Doerken, B. and Janz, M.
Leukemia 29 (5): 1213-1218. May 2015

BAY 43-9006/Sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines.
Ullrich, K. and Wurster, K.D. and Lamprecht, B. and Koechert, K. and Engert, A. and Doerken, B. and Janz, M. and Mathas, S.
British Journal of Haematology 155 (3): 398-402. November 2011

Synovialsarkome der Extremitaeten - Ergebnisse chirurgischer und multimodaler Therapie [Synovial sarcoma of the extremities. Results of surgical and multimodal therapy].
Ulmer, C. and Kettelhack, C. and Tunn, P.U. and Reichardt, P. and Hohenberger, P. and Schlag, P.M.
Chirurg 74 (4): 370-374. April 2003

Reduced-intensity conditioning using fludarabine and antithymocyte globulin alone allows stable engraftment in a patient with Dyskeratosis congenita.
Vuong, L.G. and Hemmati, P.G. and Neuburger, S. and Terwey, T.H. and Vulliamy, T. and Dokal, I. and Le Coutre, P. and Doerken, B. and Arnold, R.
Acta Haematologica 124 (4): 200-203. December 2010

Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood.
Wada, M. and Bartram, C.R. and Nakamura, H. and Hachiya, M. and Chen, D.L. and Borenstein, J. and Miller, C.W. and Ludwig, L. and Hansen-Hagge, T.E. and Ludwig, W.D. and Reiter, A. and Mizoguchi, H. and Hoeffler, H.P.
Blood 82 (10): 3163-3169. 15 November 1993

Epigenetic and genetic analysis of the survivin promoter in acute myeloid leukemia.
Wagner, M. and Schmelz, K. and Doerken, B. and Tamm, I.
Leukemia Research 32 (7): 1054-1060. July 2008

Transcriptional regulation of human survivin by early growth response (Egr)-1 transcription factor.
Wagner, M. and Schmelz, K. and Doerken, B. and Tamm, I.
International Journal of Cancer 122 (6): 1278-1287. 15 March 2008

In vivo expression of survivin and its splice variant survivin-2B: Impact on clinical outcome in acute myeloid leukemia.
Wagner, M. and Schmelz, K. and Wuchter, C. and Ludwig, W.D. and Doerken, B. and Tamm, I.
International Journal of Cancer 119 : 1291-1297. 15 September 2006

Author reply: Polyclonal resistance in gastrointestinal stromal tumor treated with sequential kinase inhibitors.
Wardelmann, E. and Biermann, K. and Merkelbach-Bruse, S. and Thomas, N. and Schildhaus, H.U. and Heinicke, T. and Speidel, N. and Pietsch, T. and Buettner, R. and Pink, D. and Reichardt, P. and Hohenberger, P.
Clinical Cancer Research 12 (20): 6206-6207. 15 October 2006

Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate.
Wardelmann, E. and Merkelbach-Bruse, S. and Pauls, K. and Thomas, N. and Schildhaus, H.U. and Heinicke, T. and Speidel, N. and Pietsch, T. and Buettner, R. and Pink, D. and Reichardt, P. and Hohenberger, P.
Clinical Cancer Research 12 : 1743-1749. 15 March 2006

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A. and Grau, M. and Erdmann, T. and Merkel, O. and Sobhiafshar, U. and Anagnostopoulos, I. and Hummel, M. and Siegert, A. and Hayford, C. and Madle, H. and Wollert-Wulf, B. and Fichtner, I. and Dörken, B. and Dirnhofer, S. and Mathas, S. and Janz, M. and Emre, N.C.T. and Rosenwald, A. and Ott, G. and Lenz, P. and Tzankov, A. and Lenz, G.
Blood 125 (1): 124-132. 1 January 2015

MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.
Wenzel, S.S. and Grau, M. and Mavis, C. and Hailfinger, S. and Wolf, A. and Madle, H. and Deeb, G. and Doerken, B. and Thome, M. and Lenz, P. and Dirnhofer, S. and Hernandez-Ilizaliturri, F.J. and Tzankov, A. and Lenz, G.
Leukemia 27 (6): 1381-1390. June 2013

CD52 is not a promising immunotherapy target for most patients with multiple myeloma.
Westermann, J. and Maschmeyer, G. and Lessen, A. and Doerken, B. and Pezzutto, A.
International Journal of Hematology 82 : 248-250. 1 October 2005

C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
Wethmar, K. and Begay, V. and Smink, J.J. and Zaragoza, K. and Wiesenthal, V. and Doerken, B. and Calkhoven, C.F. and Leutz, A.
Genes & Development 24 (1): 15-20. 1 January 2010

Transition from an autoimmune-prone state to fatal autoimmune disease in CCR7 and RORγt double-deficient mice is dependent on gut microbiota.
Wichner, K. and Fischer, A. and Winter, S. and Tetzlaff, S. and Heimesaat, M.M. and Bereswill, S. and Rehm, A. and Lipp, M. and Höpken, U.E.
Journal of Autoimmunity 47 : 58-72. December 2013

Dysregulated development of IL-17-and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORγt.
Wichner, K. and Stauss, D. and Kampfrath, B. and Krüger, K. and Müller, G. and Rehm, A. and Lipp, M. and Höpken, U.E.
FASEB Journal 30 (2): 761-774. February 2016

Induction of ceramide-mediated apoptosis by the anticancer pPhospholipid analog, hexadecylphosphocholine.
Wieder, T. and Orfanos, C.E. and Geilen, C.C.
Journal of Biological Chemistry 273 (18): 11025-11031. 1 May 1998

Manifestation of spontaneous and early autoimmune gastritis in CCR7-deficient mice.
Winter, S. and Rehm, A. and Wichner, K. and Scheel, T. and Batra, A. and Siegmund, B. and Berek, C. and Lipp, M. and Hoepken, U.E.
American Journal of Pathology 179 (2): 754-765. August 2011

Role of EBAG9 protein in coat protein complex I-dependent glycoprotein maturation and secretion processes in tumor cells.
Wolf, J. and Reimer, T.A. and Schuck, S. and Rueder, C. and Gerlach, K. and Mueller, E.C. and Otto, A. and Doerken, B. and Rehm, A.
FASEB Journal 24 (10): 4000-4019. October 2010

Coexpression of p21WAF1/CIP1 in adenovirus vector transfected human primary hepatocytes prevents apoptosis resulting in improved transgene expression.
Wolff, G. and Schumacher, A. and Nuessler, A.K. and Ruppert, V. and Karawajew, L. and Wehnes, E. and Neuhaus, P. and Doerken, B.
Gene Therapy 10 (8): 668-677. April 2003

Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract.
Worgall, S. and Leopold, P.L. and Wolff, G. and Ferris, B. and Van Roijen, N. and Crystal, R.G.
Human Gene Therapy 8 (14): 1675-1684. 20 September 1997

Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.
Wurster, K.D. and Hummel, F. and Richter, J. and Giefing, M. and Hartmann, S. and Hansmann, M.L. and Kreher, S. and Köchert, K. and Krappmann, D. and Klapper, W. and Hummel, M. and Wenzel, S.S. and Lenz, G. and Janz, M. and Dörken, B. and Siebert, R. and Mathas, S.
Leukemia 31 (3): 602-613. March 2017

Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma.
Yu, Y. and Schleich, K. and Yue, B. and Ji, S. and Lohneis, P. and Kemper, K. and Silvis, M.S. and Qutob, N. and van Rooijen, E. and Werner-Klein, M. and Li, L. and Dhawan, D. and Meierjohann, S. and Reimann, M. and Elkahloun, A. and Treitschke, S. and Dörken, B. and Speck, C. and Mallette, F.A. and Zon, L.I. and Holmen, S.L. and Peeper, D.S. and Samuels, Y. and Schmitt, C.A. and Lee, S.
Cancer Cell 33 (2): 322-336. 12 February 2018

Fatal immune haemolysis due to antibodies to individual metabolites of 5-fluorouracil.
Yuerek, S. and Riess, H. and Kreher, S. and Doerken, B. and Salama, A.
Transfusion Medicine 20 (4): 265-268. 1 August 2010

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P. and Kaergel, E. and Heinig, M. and Fontaine, J.F. and Patone, G. and Muro, E.M. and Mathas, S. and Hummel, M. and Andrade-Navarro, M.A. and Hübner, N. and Scheidereit, C.
Genome Medicine 8 (1): 28. 17 March 2016

Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogeneic stem cell transplantation.
le Coutre, P. and Meisel, H. and Hofmann, J. and Roecken, C. and Vuong, G.L. and Neuburger, S. and Hemmati, P.G. and Doerken, B. and Arnold, R.
Gut 58 (5): 699-702. May 2009

Post-transplantation chronic myeloid leukemia.
le Coutre, P. and Schwarz, M. and Daniel, P. and Doerken, B.
Clinical Advances in Hematology & Oncology 9 (8): 627-629. August 2011

Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.
van Dongen, J.J. and Seriu, T. and Panzer-Gruemayer, E.R. and Biondi, A. and Pongers-Willemse, M.J. and Corral, L. and Stolz, F. and Schrappe, M. and Masera, G. and Kamps, W.A. and Gadner, H. and van Wering, E.R. and Ludwig, W.D. and Basso, G. and de Bruijn, M.A. and Cazzaniga, G. and Hettinger, K. and van der Does-van den Berg, A. and Hop, W.C. and Riehm, H. and Bartram, C.R.
Lancet 352 (9142): 1731-1738. 28 November 1998

Falcke, Martin

Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Moenke, G. and Cristiano, E. and Finzel, A. and Friedrich, D. and Herzel, H. and Falcke, M. and Loewer, A.
bioRxiv : 068668. 28 November 2016

Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Mönke, G. and Cristiano, E. and Finzel, A. and Friedrich, D. and Herzel, H. and Falcke, M. and Loewer, A.
Scientific Reports 7 : 46571. 18 April 2017

Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C. and Hegde, B.G. and Morén, B. and Behrmann, E. and Mielke, T. and Moenke, G. and Spahn, C.M. and Lundmark, R. and Daumke, O. and Langen, R.
Structure 22 (3): 409-420. 4 March 2014

Falk, Kirsten

Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.
Bilic, I. and Koesters, C. and Unger, B. and Sekimata, M. and Hertweck, A. and Maschek, R. and Wilson, C.B. and Ellmeier, W.
Nature Immunology 7 (4): 392-400. April 2006

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G. and Kleinewietfeld, M. and Di Mitri, D. and Sternjak, A. and Diamantini, A. and Giometto, R. and Hoepner, S. and Centonze, D. and Bernardi, G. and Dell'Acqua, M.L. and Rossini, P.M. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 110 (4): 1225-1232. 15 August 2007

Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes.
Burster, T. and Beck, A. and Tolosa, E. and Marin-Esteban, V. and Roetzschke, O. and Falk, K. and Lautwein, A. and Reich, M. and Brandenburg, J. and Schwarz, G. and Wiendl, H. and Melms, A. and Lehmann, R. and Stevanovic, S. and Kalbacher, H. and Driessen, C.
Journal of Immunology 172 (9): 5495-5503. 1 January 2004

Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro.
Burster, T. and Becker, A. and Poeschel, S. and Oren, A. and Baechle, D. and Reich, M. and Roetzschke, O. and Falk, K. and Boehm, B.O. and Youssef, S. and Kalbacher, H. and Overkleeft, H. and Tolosa, E. and Driessen, C.
Immunology 121 (1): 82-93. May 2007

Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions.
Burster, T. and Marin-Esteban, V. and Boehm, B.O. and Dunn, S. and Roetzschke, O. and Falk, K. and Weber, E. and Verhelst, S.H. and Kalbacher, H. and Driessen, C.
Biochemical Pharmacology 74 (10): 1514-1523. 15 November 2007

Enhancement of tumour-specific immune responses in vivo by 'MHC Loading-Enhancer' (MLE).
Dickhaut, K. and Hoepner, S. and Eckhard, J. and Wiesmueller, K.H. and Schindler, L. and Jung, G. and Falk, K. and Roetzschke, O.
PLoS ONE 4 (9): e6811. 7 September 2009

Aenderung des Beladungszustandes von MHC-Molekuelen [Change of the load state of MHC molecules].
Falk, K. and Roetzschke, O.
DE102004054545A1 ; WO0629891. 6 April 2006

Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: enhanced in vivo potency of encephalitogenic peptides.
Falk, K. and Roetzschke, O. and Santambrogio, L. and Dorf, M.E. and Brosnan, C. and Strominger, J.L.
Journal of Experimental Medicine 191 (4): 717-730. 21 February 2000

Pillars article: allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991. 351: 290-296.
Falk, K. and Roetzschke, O. and Stevanovic, S. and Jung, G. and Rammensee, H.G.
Journal of Immunology 177 (5): 2741-2747. 1 September 2006

Verfahren zur Verbesserung von immuntherapeutischen Verfahren [Method for improving methods of immunotherapy].
Falk, K. and Roetzschke, O. and Strominger, J.
WO0316512. 27 February 2003

Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Guenther, S. and Schlundt, A. and Sticht, J. and Roske, Y. and Heinemann, U. and Wiesmueller, K.H. and Jung, G. and Falk, K. and Roetzschke, O. and Freund, C.
Proceedings of the National Academy of Sciences of the United States of America 107 (51): 22219-22224. 21 December 2010

Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.
Gupta, S. and Hoepner, S. and Rupp, B. and Guenther, S. and Dickhaut, K. and Agarwal, N. and Cardoso, M.C. and Kuehne, R. and Wiesmueller, K.H. and Jung, G. and Falk, K. and Roetzschke, O.
PLoS ONE 3 (3): e1814. 19 March 2008

Small organic compounds enhance antigen-loading of class II MHC proteins by targeting the polymorphic P1 pocket.
Hoepner, S. and Dickhaut, K. and Hofstaetter, M. and Kraemer, H. and Rueckerl, D. and Soederhaell, J.A. and Gupta, S. and Marin-Esteban, V. and Kuehne, R. and Freund, C. and Jung, G. and Falk, K. and Roetzschke, O.
Journal of Biological Chemistry 281 (50): 38535-38542. 15 December 2006

Hydrolysis of extracellular ATP by CD39+ Treg cells: context matters!
Kleinewietfeld, M. and Dimitri, D. and Sternjak, A. and Diamantini, A. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 111 (2): 965-966. 15 January 2008

CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T cell subset.
Kleinewietfeld, M. and Puentes, F. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 105 (7): 2877-2886. 1 January 2005

CD49d provides access to 'untouched' human Foxp3+ Treg free of contaminating effector cells.
Kleinewietfeld, M. and Starke, M. and Mitri, D.D. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 113 (4): 827-836. 22 January 2009

TAP-independent antigen presentation on MHC class I molecules: lessons from Epstein-Barr virus.
Lautscham, G. and Rickinson, A. and Blake, N.
Microbes and Infection 5 (4): 291-299. April 2003

Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity.
Mailer, R.K. and Falk, K. and Roetzschke, O.
PLoS ONE 4 (7): e6104. 1 July 2009

'Chemical analogues' of HLA-DM can induce a peptide-receptive state in HLA-DR molecules.
Marin-Esteban, V. and Falk, K. and Roetzschke, O.
Journal of Biological Chemistry 279 (49): 50684-50690. 20 September 2004

Small-molecular compounds enhance the loading of APC with encephalitogenic MBP protein.
Marin-Esteban, V. and Falk, K. and Roetzschke, O.
Journal of Autoimmunity 20 (1): 63-69. February 2003

Production of neuroprotective NGF in astrocyte-T helper cell cocultures is upregulated following antigen recognition.
Oren, A. and Falk, K. and Roetzschke, O. and Bechmann, I. and Nitsch, R. and Gimsa, U.
Journal of Neuroimmunology 149 (1-2): 59-65. April 2004

Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.
Piaggio, E. and Mars, L.T. and Cassan, C. and Cabarrocas, J. and Hofstaetter, M. and Desbois, S. and Bergereau, E. and Roetzschke, O. and Falk, K. and Liblau, R.S.
Proceedings of the National Academy of Sciences of the United States of America 104 (22): 9393-9398. 29 May 2007

Active suppression induced by repetitive self-epitopes protects against EAE development.
Puentes, F. and Dickhaut, K. and Hofstaetter, M. and Falk, K. and Roetzschke, O.
PLoS ONE 8 (5): e64888. 30 May 2013

Immune modulation and prevention of autoimmune disease by repeated sequences from parasites linked to self antigens.
Puentes, F. and Dickhaut, K. and Hofstaetter, M. and Pfeil, J. and Lauer, U. and Hamann, A. and Hoffmann, U. and Falk, K. and Roetzschke, O.
Journal of Neuroimmune Pharmacology 11 (4): 749-762. December 2016

MHC class I-restricted antigen processing--lessons from natural ligands.
Rammensee, H.G. and Roetzschke, O. and Falk, K.
Chemical Immunology 57 : 113-133. 1993

In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.
Roetzschke, O. and Borsellino, G. and Battistini, L. and Falk, K. and Kleinewietfeld, M.
Blood 113 (9): 2119-2120. 26 February 2009

Regulatory T cells in transplantation: does extracellular adenosine triphosphate metabolism through CD39 play a crucial role?
Salcido-Ochoa, F. and Tsang, J. and Tam, P. and Falk, K. and Roetzschke, O.
Transplantation Reviews 24 (2): 52-66. April 2010

A xenon-129 biosensor for monitoring MHC-peptide interactions.
Schlundt, A. and Kilian, W. and Beyermann, M. and Sticht, J. and Guenther, S. and Hoepner, S. and Falk, K. and Roetzschke, O. and Mitschang, L. and Freund, C.
Angewandte Chemie International Edition 48 (23): 4142-4145. 25 May 2009

Fichtner, Iduna

Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice.
Abolhassani, M. and Guais, A. and Sanders, E. and Campion, F. and Fichtner, I. and Bonte, J. and Baronzio, G. and Fiorentini, G. and Israel, M. and Schwartz, L.
Investigational New Drugs 30 (4): 1331-1342. August 2012

Comparative evaluation of the biological properties of reducible and acid-sensitive folate prodrugs of a highly potent doxorubicin derivative.
Abu Ajaj, K. and El-Abadla, N. and Welker, P. and Azab, S. and Zeisig, R. and Fichtner, I. and Kratz, F.
European Journal of Cancer 48 (13): 2054-2065. September 2012

In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B.
Abu Ajaj, K. and Graeser, R. and Fichtner, I. and Kratz, F.
Cancer Chemotherapy and Pharmacology 64 (2): 413-418. July 2009

Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel.
Adema, A.D. and Laan, A.C. and Myhren, F. and Fichtner, I. and Verheul, H.M. and Sandvold, M.L. and Peters, G.J.
International Journal of Oncology 36 (1): 285-294. 1 January 2010

Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells.
Bachmeier, B. and Fichtner, I. and Killian, P.H. and Kronski, E. and Pfeffer, U. and Efferth, T.
PLoS ONE 6 (5): e20550. 26 May 2011

Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo.
Bannon, J.H. and Fichtner, I. and O'Neill, A. and Pampillon, C. and Sweeney, N.J. and Strohfeldt, K. and Watson, R.W. and Tacke, M. and McGee, M.M.
British Journal of Cancer 97 (9): 1234-1241. 5 November 2007

Synergistic activity of bortezomib and HDACis in preclinical models of B-cell precursor acute lymphoblastic leukemia via modulation of p53, PI3K/AKT and NF-κB.
Bastian, L. and Hof, J. and Pfau, M. and Fichtner, I. and Eckert, C. and Henze, G. and Prada, J. and von Stackelberg, A. and Seeger, K. and Shalapour, S.
Clinical Cancer Research 19 (6): 1445-1457. 15 March 2013

Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM.
Becker, M. and Sommer, A. and Kraetzschmar, J.R. and Seidel, H. and Pohlenz, H.D. and Fichtner, I.
Molecular Cancer Therapeutics 4 : 151-170. 1 January 2005

Loss of tumourigenicity of stably ERbeta-transfected MCF-7 breast cancer cells.
Behrens, D. and Gill, J.H. and Fichtner, I.
Molecular and Cellular Endocrinology 274 (1-2): 19-29. 15 August 2007

The mTOR pathway inhibitor RAD001 (everolimus) is highly efficacious in tamoxifen-sensitive and -resistant breast cancer xenografts.
Behrens, D. and Lykkesfeldt, A.E. and Fichtner, I.
Targeted Oncology 2 (3): 135-144. July 2007

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly.
Belz, K. and Schoeneberger, H. and Wehner, S. and Weigert, A. and Boenig, H. and Klingebiel, T. and Fichtner, I. and Fulda, S.
Blood 124 (2): 240-250. 10 July 2014

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.
Bergman, A.M. and Adema, A.D. and Balzarini, J. and Bruheim, S. and Fichtner, I. and Noordhuis, P. and Fodstad, O. and Myhren, F. and Sandvold, M.L. and Hendriks, H.R. and Peters, G.J.
Investigational New Drugs 29 (3): 456-466. June 2011

Quinols as novel therapeutic agents. 2.(1) 4-(1-arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.
Berry, J.M. and Bradshaw, T.D. and Fichtner, I. and Ren, R. and Schwalbe, C.H. and Wells, G. and Chew, E.H. and Stevens, M.F. and Westwell, A.D.
Journal of Medicinal Chemistry 48 : 639-644. 27 January 2005

Proteomics of xenografted human breast cancer indicates novel targets related to tamoxifen resistance.
Besada, V. and Diaz, M. and Becker, M. and Ramos, Y. and Castellanos-Serra, L. and Fichtner, I.
Proteomics 6 (3): 1038-1048. February 2006

In vitro activity and mechanism of action of a duplex and multidrug of ethynylcytidine and 5-fluorodeoxyuridine.
Bijnsdorp, I. and Schwendener, R. and Schott, H. and Schott, S. and Fichtner, I. and Honeywell, R. and Losekoot, N. and Laan, A. and Peters, G.J.
Nucleic Acids Symposium Series 52 : 651. 8 September 2008

Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.
Bijnsdorp, I.V. and Schwendener, R.A. and Schott, H. and Fichtner, I. and Smid, K. and Laan, A.C. and Schott, S. and Losekoot, N. and Honeywell, R.J. and Peters, G.J.
Investigational New Drugs 29 (2): 248-257. April 2011

In vivo and in vitro activity and mechanism of action of the multidrug cytarabine-L-glycerylyl-fluorodeoxyuridine.
Bijnsdorp, I.V. and Schwendener, R.A. and Schott, H. and Fichtner, I. and Smid, K. and Schott, S. and Laan, A.C. and Peters, G.J.
Nucleosides Nucleotides & Nucleic Acids 26 (10-12): 1619-1624. 5 December 2007

Efficacy of MS-275, a selective inhibitor of class I histone deacetylases, in human colon cancer models.
Bracker, T.U. and Sommer, A. and Fichtner, I. and Faus, H. and Haendler, B. and Hess-Stumpp, H.
International Journal of Oncology 35 (4): 909-920. October 2009

MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors.
Brischwein, K. and Schlereth, B. and Guller, B. and Steiger, C. and Wolf, A. and Lutterbuese, R. and Offner, S. and Locher, M. and Urbig, T. and Raum, T. and Kleindienst, P. and Wimberger, P. and Kimmig, R. and Fichtner, I. and Kufer, P. and Hofmeister, R. and da Silva, A.J. and Baeuerle, P.A.
Molecular Immunology 43 (8): 1129-1143. March 2006

Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy.
Brueckner, B. and Rius, M. and Rivera Markelova, M. and Fichtner, I. and Hals, P.A. and Sandvold, M.L. and Lyko, F.
Molecular Cancer Therapeutics 9 (5): 1256-1264. May 2010

Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly (ethylene glycol) shell.
Calderon, M. and Welker, P. and Licha, K. and Fichtner, I. and Graeser, R. and Haag, R. and Kratz, F.
Journal of Controlled Release 151 (3): 295-301. 10 May 2011

The alpha4beta1 and alpha5beta1 integrins mediate engraftment of granulocyte-colony-stimulating factor-mobilized human hematopoietic progenitor cells.
Carstanjen, D. and Gross, A. and Kosova, N. and Fichtner, I. and Salama, A.
Transfusion 45 : 1192-1200. 1 July 2005

Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.
Dahlmann, M. and Sack, U. and Herrmann, P. and Lemm, M. and Fichtner, I. and Schlag, P.M. and Stein, U.
Oncotarget 3 (8): 783-797. 7 August 2012

Suspension medium influences interaction of mesenchymal stromal cells with endothelium and pulmonary toxicity after transplantation in mice.
Deak, E. and Ruester, B. and Keller, L. and Eckert, K. and Fichtner, I. and Seifried, E. and Henschler, R.
Cytotherapy 12 (2): 260-264. April 2010

Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies.
Diaz Miqueli, A. and Rolff, J. and Lemm, M. and Fichtner, I. and Perez, R. and Montero, E.
British Journal of Cancer 100 (6): 950-958. 24 March 2009

Antitumor activity of Titanocene Y in xenografted PC3 tumors in mice.
Dowling, C.M. and Claffey, J. and Cuffe, S. and Fichtner, I. and Pampillon, C. and Sweeney, N.J. and Strohfeldt, K. and Watson, R.W. and Tacke, M.
Letters in Drug Design & Discovery 5 (2): 141-144. March 2008

T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3-bispecific single-chain antibody construct1.
Dreier, T. and Baeuerle, P.A. and Fichtner, I. and Gruen, M. and Schlereth, B. and Lorenczewski, G. and Kufer, P. and Lutterbuese, R. and Riethmueller, G. and Gjorstrup, P. and Bargou, R.C.
Journal of Immunology 170 (8): 4397-4402. 15 April 2003

Histone deacetylase inhibitors have antitumor activity in two NOD/SCID mouse models of B-cell precursor childhood acute lymphoblastic leukemia.
Einsiedel, H.G. and Kawan, L. and Eckert, C. and Witt, O. and Fichtner, I. and Henze, G. and Seeger, K.
Leukemia 20 (8): 1435-1436. August 2006

CS-1, a novel c-kithi+ acute myeloid leukemia cell line with dendritic cell differentiation capacity and absent immunogenicity.
Erben, U. and Thiel, E. and Bittroff-Leben, A. and Schoch, C. and Fichtner, I. and Durkop, H. and Notter, M.
International Journal of Cancer 105 (2): 232-240. 10 June 2003

Praeklinische Daten als Grundlage fuer die Konzeption klinischer Studien [Preclinical data as basis for the design of clinical studies].
Fichtner, I.
Onkologie 31 (Suppl. 2): 34-38. May 2008

Antileukaemic activity of treosulfan in xenografted human acute lymphoblastic leukaemias (ALL).
Fichtner, I. and Becker, M. and Baumgart, J.
European Journal of Cancer 39 (6): 801-807. April 2003

Differential protein expression pattern in tamoxifen-sensitive and -resistant breast cancer xenografts.
Fichtner, I. and Becker, M. and Besada, V. and Castellanos-Serra, L.
International Journal of Clinical Pharmacology and Therapeutics 42 (11): 632-634. November 2004

In vivo models for endocrine-dependent breast carcinomas: special considerations of clinical relevance.
Fichtner, I. and Becker, M. and Zeisig, R. and Sommer, A.
European Journal of Cancer 40 (6): 845-851. April 2004

The antiangiogenic and antitumoral activity of titanocene Y* in vivo.
Fichtner, I. and Behrens, D. and Claffey, J. and Deally, A. and Gleeson, B. and Patil, S. and Weber, H. and Tacke, M.
Letters in Drug Design & Discovery 8 (4): 302-307. May 2011

Antitumor activity of oxali-titanocene Y in xenografted CAKI-1 tumors in mice.
Fichtner, I. and Behrens, D. and Claffey, J. and Gleeson, B. and Hogan, M. and Wallis, D. and Weber, H. and Tacke, M.
Letters in Drug Design & Discovery 5 (8): 489-493. December 2008

In vitro and in vivo investigations into the carbene silver acetate anticancer drug candidate SBC1.
Fichtner, I. and Cinatl, J. and Michaelis, M. and Sanders, L.C. and Hilger, R. and Kennedy, B.N. and Reynolds, A.L. and Hackenberg, F. and Lally, G. and Quinn, S.J. and McRae, I. and Tacke, M.
Letters in Drug Design & Discovery 9 (9): 815-822. November 2012

Antitumor activity of vanadocene Y and its selenocyanate derivative in xenografted CAKI-1 tumors in mice.
Fichtner, I. and Claffey, J. and Deally, A. and Gleeson, B. and Hogan, M. and Rivera Markelova, M. and Mueller-Bunz, H. and Weber, H. and Tacke, M.
Journal of Organometallic Chemistry 695 (8): 1175-1181. 15 April 2010

The experimental antitumor agents phortress and doxorubicin are equiactive against human-derived breast carcinoma xenograft models.
Fichtner, I. and Monks, A. and Hose, C. and Stevens, M.F. and Bradshaw, T.D.
Breast Cancer Research and Treatment 87 (1): 97-107. 1 September 2004

Chemo- and radiation sensitivity of xenografted acute lymphoblastic leukemias-correlation to the expression of multidrug resistance proteins.
Fichtner, I. and Paal, K. and Borgmann, A. and Badiali, L. and Wurm, R. and Henze, G.
Anticancer Research 23 (3): 2657-2664. May 2003

Anti-tumor activity of Titanocene Y in xenografted Caki-1 tumors in mice.
Fichtner, I. and Pampillon, C. and Sweeney, N.J. and Strohfeldt, K. and Tacke, M.
Anti-Cancer Drugs 17 (3): 333-336. March 2006

In vivo characterization of immunogenicity of a mitoxantrone-resistant murine P388 leukemia.
Fichtner, I. and Reipert, B. and Becker, M. and Lemm, M.
In Vivo 7 (1): 73-80. January 1993

Animal experiments - An essential component for the development of liposomal anticancer agents.
Fichtner, I. and Reszka, R. and Arndt, D. and Zeisig, R.
Journal of Liposome Research 13 (1): 9-15. 3 December 2003

Stimulation of hematopoiesis by carboplatin-liposomes.
Fichtner, I. and Reszka, R. and Becker, M. and Lemm, M. and Richter, J. and Rudolph, M.
Journal of Liposome Research 4 (1): 43-69. March 1994

Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.
Fichtner, I. and Rolff, J. and Soong, R. and Hoffmann, J. and Hammer, S. and Sommer, A. and Becker, M. and Merk, J.
Clinical Cancer Research 14 (20): 6456-6468. 15 October 2008

Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas.
Fichtner, I. and Slisow, W. and Gill, J. and Becker, M. and Elbe, B. and Hillebrand, T. and Bibby, M.
European Journal of Cancer 40 (2): 298-307. January 2004

Animal models for personalized treatment options.
Fichtner, I. and Klinghammer, K. and Behrens, D. and Flechsig, S. and Rolff, J. and Becker, M. and Wulf-Goldenberg, A. and Stecklum, M. and Rivera, M. and Brzezicha, B. and Jandrig, B. and Hoffmann, J.
International Journal of Clinical Pharmacology and Therapeutics 55 (8): 698-700. August 2017

Verfahren zur Diagnose und Therapie von antioestrogentherapieresistenten Brusttumoren [Diagnosis and therapy of breast tumours resistant to antiestrogen treatment].
Fichtner, I. and Becker, M. and Besada-Perez, V. and Castellanos-Serra, L.
DE10310198A1 ; WO0408137. 22 January 2004

Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma.
Friesen, C. and Hormann, I. and Roscher, M. and Fichtner, I. and Alt, A. and Hilger, R. and Debatin, K.M. and Miltner, E.
Cell Cycle 13 (10): 1560-1570. 15 May 2014

Cell death sensitization of leukemia cells by opioid receptor activation.
Friesen, C. and Roscher, M. and Hormann, I. and Fichtner, I. and Alt, A. and Hilger, R.A. and Debatin, K.M. and Miltner, E.
Oncotarget 4 (5): 677-690. 16 April 2013

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J. and Morkel, M. and Besser, D. and Budczies, J. and Kosel, F. and Brembeck, F.H. and Stein, U. and Fichtner, I. and Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

Interwoven four-compartment capillary membrane technology for three-dimensional perfusion with decentralized mass exchange to scale up embryonic stem cell culture.
Gerlach, J. and Luebberstedt, M. and Edsbagge, J. and Ring, A. and Hout, M. and Baun, M. and Rossberg, I. and Knoespel, F. and Peters, G. and Eckert, K. and Wulf-Goldenberg, A. and Bjoerquist, P. and Stachelscheid, H. and Urbaniak, T. and Schatten, G. and Miki, T. and Schmelzer, E. and Zeilinger, K.
Cells Tissues Organs 192 (1): 39-49. June 2010

The severe combined immunodeficient-human peripheral blood stem cell (SCID-huPBSC) mouse: a xenotransplant model for huPBSC-initiated hematopoiesis.
Goan, S.R. and Fichtner, I. and Just, U. and Karawajew, L. and Schultze, W. and Krause, K.P. and von Harsdorf, S. and von Schilling, C. and Herrmann, F.
Blood 86 (1): 89-100. 1 July 1995

Tissue factor expression pattern in human non-small cell lung cancer tissues indicate increased blood thrombogenicity and tumor metastasis.
Goldin-Lang, P. and Tran, Q.V. and Fichtner, I. and Eisenreich, A. and Antoniak, S. and Schulze, K. and Coupland, S.E. and Poller, W. and Schultheiss, H.P. and Rauch, U.
Oncology Reports 20 (1): 123-128. July 2008

INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model.
Graeser, R. and Esser, N. and Unger, H. and Fichtner, I. and Zhu, A. and Unger, C. and Kratz, F.
Investigational New Drugs 28 (1): 14-19. February 2010

Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology.
Gries, J. and Schumacher, D. and Arand, J. and Lutsik, P. and Markelova, M.R. and Fichtner, I. and Walter, J. and Sers, C. and Tierling, S.
Epigenetics 8 (7): 765-771. July 2013

Comparative profiling of the novel epothilone, sagopilone, in xenografts derived from primary non-small cell lung cancer.
Hammer, S. and Sommer, A. and Fichtner, I. and Becker, M. and Rolff, J. and Merk, J. and Klar, U. and Hoffmann, J.
Clinical Cancer Research 16 (5): 1452-1465. 1 March 2010

Comparison of the effect of orally administered soluble β-(1-3),(1-6)-D-glucan and of G-CSF on the recovery of murine hematopoiesis.
Harnack, U. and Eckert, K. and Fichtner, I. and Pecher, G.
In Vivo 24 (1): 59-63. January 2010

Oral administration of a soluble 1-3, 1-6 beta-glucan during prophylactic survivin peptide vaccination diminishes growth of a B cell lymphoma in mice.
Harnack, U. and Eckert, K. and Fichtner, I. and Pecher, G.
International Immunopharmacology 9 (11): 1298-1303. October 2009

Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative.
Hendriks, H.R. and Govaerts, A.S. and Fichtner, I. and Burtles, S. and Westwell, A.D. and Peters, G.J.
British Journal of Cancer 117 (2): 195-202. 11 July 2017

Transplantation of human acute myeloid leukemia (AML) cells in immunodeficient mice reveals altered cell surface phenotypes and expression of human endothelial markers.
Henschler, R. and Goettig, S. and Junghahn, I. and Bug, G. and Seifried, E. and Mueller, A.M. and Fichtner, I.
Leukemia Research 29 (10): 1191-1199. 1 January 2005

Angiotensin-(1-7) stimulates hematopoietic progenitor cells in vitro and in vivo.
Heringer-Walther, S. and Eckert, K. and Schumacher, S.M. and Uharek, L. and Wulf-Goldenberg, A. and Gembardt, F. and Fichtner, I. and Schultheiss, H.P. and Rodgers, K. and Walther, T.
Haematologica 94 (6): 857-860. June 2009

Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
Hoffmann, J. and Fichtner, I. and Lemm, M. and Lienau, P. and Hess-Stumpp, H. and Rotgeri, A. and Hofmann, B. and Klar, U.
Neuro Oncology 11 (2): 158-166. April 2009

Combined Wnt/β-catenin, met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome.
Holland, J.D. and Györffy, B. and Vogel, R. and Eckert, K. and Valenti, G. and Fang, L. and Lohneis, P. and Elezkurtaj, S. and Ziebold, U. and Birchmeier, W.
Cell Reports 5 (5): 1214-1227. 12 December 2013

Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib.
Huelsmann, H.J. and Rolff, J. and Bender, C. and Jarahian, M. and Korf, U. and Herwig, R. and Froehlich, H. and Thomas, M. and Merk, J. and Fichtner, I. and Sueltmann, H. and Kuner, R.
Lung Cancer 86 (2): 151-157. November 2014

Poly(ethylene oxide)-block-poly(glutamic acid) coated maghemite nanoparticles: in vitro characterization and in vivo behaviour.
Kaufner, L. and Cartier, R. and Wuestneck, R. and Fichtner, I. and Pietschmann, S. and Bruhn, H. and Schuett, D. and Thuenemann, A.F. and Pison, U.
Nanotechnology 18 (11): 115710. 21 March 2007

Effect of surface modified liposomes on the aggregation of platelets and tumor cells.
Keil, C. and Zeisig, R. and Fichtner, I.
Thrombosis and Haemostasis 94 (2): 404-411. August 2005

Transcriptional expression profile of cultured human embryonic stem cells in vitro and in vivo.
Keil, M. and Siegert, A. and Eckert, K. and Gerlach, J. and Haider, W. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 48 (3): 165-174. March 2012

A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.
Klinghammer, K. and Raguse, J.D. and Plath, T. and Albers, A.E. and Joehrens, K. and Zakarneh, A. and Brzezicha, B. and Wulf-Goldenberg, A. and Keilholz, U. and Hoffmann, J. and Fichtner, I.
International Journal of Cancer 136 (12): 2940-2948. 15 June 2015

Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: biphasic heat induction of cytosine deaminase suicide gene expression.
Kobelt, D. and Aumann, J. and Fichtner, I. and Stein, U. and Schlag, P.M. and Walther, W.
Molecular Biotechnology 46 (2): 197-205. October 2010

Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector.
Kobelt, D. and Aumann, J. and Schmidt, M. and Wittig, B. and Fichtner, I. and Behrens, D. and Lemm, M. and Freundt, G. and Schlag, P.M. and Walther, W.
Molecular Oncology 8 (3): 609-619. May 2014

Membrane switch hypothesis. 1. Cell density influences lateral domain structure of tumor cell membranes.
Koklic, T. and Pirs, M. and Zeisig, R. and Abramovic, Z. and Sentjurc, M.
Journal of Chemical Information and Modeling 45 (6): 1701-1707. 28 November 2005

Interaction of alkylphospholipid liposomes with MT-3 breast-cancer cells depends critically on cholesterol concentration.
Koklic, T. and Zeisig, R. and Sentjurc, M.
Biochimica et Biophysica Acta - Biomembranes 1778 (12): 2682-2689. December 2008

Evaluation of combination therapy schedules of doxorubicin and an acid-sensitive albumin-binding prodrug of doxorubicin in the MIA PaCa-2 pancreatic xenograft model.
Kratz, F. and Azab, S. and Zeisig, R. and Fichtner, I. and Warnecke, A.
International Journal of Pharmaceutics 441 (1-2): 499-506. 30 January 2013

Combination therapy with the albumin-binding prodrug of doxorubicin (INNO-206) and doxorubicin achieves complete remissions and improves tolerability in an ovarian A2780 xenograft model.
Kratz, F. and Fichtner, I. and Graeser, R.
Investigational New Drugs 30 (4): 1743-1749. August 2012

Development of albumin-binding doxorubicin prodrugs that are cleaved by prostate-specific antigen.
Kratz, F. and Mansour, A. and Soltau, J. and Warnecke, A. and Fichtner, I. and Unger, C. and Drevs, J.
Archiv der Pharmazie 338 : 462-472. 7 October 2005

Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas.
Kratzsch, T. and Kuhn, S.A. and Joedicke, A. and Hanisch, U.K. and Vajkoczy, P. and Hoffmann, J. and Fichtner, I.
Journal of Cancer Research and Clinical Oncology 144 (5): 809-819. May 2018

Testing of SNS-032 in a panel of human neuroblastoma cell lines with acquired resistance to a broad range of drugs.
Loeschmann, N. and Michaelis, M. and Rothweiler, F. and Zehner, R. and Cinatl, J. and Voges, Y. and Sharifi, M. and Riecken, K. and Meyer, J. and von Deimling, A. and Fichtner, I. and Ghafourian, T. and Westermann, F. and Cinatl Jr., J.
Translational Oncology 6 (6): 685-696. December 2013

A new approach for the treatment of malignant melanoma: Enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2.
Mansour, A.M. and Drevs, J. and Esser, N. and Hamada, F.M. and Badary, O.A. and Unger, C. and Fichtner, I. and Kratz, F.
Cancer Research 63 (14): 4062-4066. 15 July 2003

In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes.
McCann, M. and Santos, A.L.S. and da Silva, B.A. and Romanos, M.T.V. and Pyrrho, A.S. and Devereux, M. and Kavanagh, K. and Fichtner, I. and Kellett, A.
Toxicology Research 1 (1): 47-54. July 2012

Patient-derived xenografts of non-small-cell lung cancer: a pre-clinical model to evaluate adjuvant chemotherapy?
Merk, J. and Rolff, J. and Becker, M. and Leschber, G. and Fichtner, I.
European Journal of Cardio-Thoracic Surgery 36 (3): 454-459. September 2009

Chemoresistance in non-small-cell lung cancer: can multidrug resistance markers predict the response of xenograft lung cancer models to chemotherapy?
Merk, J. and Rolff, J. and Dorn, C. and Leschber, G. and Fichtner, I.
European Journal of Cardio-Thoracic Surgery 40 (1): e29-e33. July 2011

Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo.
Michaelis, M. and Fichtner, I. and Behrens, D. and Haider, W. and Rothweiler, F. and Mack, A. and Cinatl, J. and Doerr, H.W. and Cinatl, J.
International Journal of Oncology 28 (2): 439-446. February 2006

Synthesis and biological evaluation of spin-labeled alkylphospholipid analogs.
Mravljak, J. and Zeisig, R. and Pecar, S.
Journal of Medicinal Chemistry 48 (20): 6393-6399. 6 October 2005

Interleukin-3 promotes proliferation and differentiation of human hematopoietic stem cells but reduces their repopulation potential in NOD/SCID mice.
Nitsche, A. and Junghahn, I. and Thulke, S. and Aumann, J. and Radonic, A. and Fichtner, I. and Siegert, W.
Stem Cells 21 (2): 236-244. March 2003

Improving the transport of chemotherapeutic drugs across the blood-brain barrier.
Orthmann, A. and Fichtner, I. and Zeisig, R.
Expert Review of Clinical Pharmacology 4 (4): 477-490. July 2011

Improved treatment of MT-3 breast cancer and brain metastases in a mouse xenograft by LRP-targeted oxaliplatin liposomes.
Orthmann, A. and Peiker, L. and Fichtner, I. and Hoffmann, A. and Hilger, R.A. and Zeisig, R.
Journal of Biomedical Nanotechnology 12 (1): 56-68. January 2016

Impact of membrane properties on uptake and transcytosis of colloidal nanocarriers across an epithelial cell barrier model.
Orthmann, A. and Zeisig, R. and Koklic, T. and Sentjurc, M. and Wiesner, B. and Lemm, M. and Fichtner, I.
Journal of Pharmaceutical Sciences 99 (5): 2423-2433. May 2010

Treatment of experimental brain metastasis with MTO-liposomes: impact of fluidity and LRP-targeting on the therapeutic result.
Orthmann, A. and Zeisig, R. and Suess, R. and Lorenz, D. and Lemm, M. and Fichtner, I.
Pharmaceutical Research 29 (7): 1949-1959. July 2012

Isolierung von Neuronen und Stammzellen fuer Nervenfasern aus einer Probe [Isolation of neurones and stem cells for nerve fibres from a sample].
Pfrieger, F.W. and Naegler, K.
EP1448764 ; WO0342374. 22 May 2003

The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells.
Redmer, T. and Welte, Y. and Behrens, D. and Fichtner, I. and Przybilla, D. and Wruck, W. and Yaspo, M.L. and Lehrach, H. and Schaefer, R. and Regenbrecht, C.R.A.
PLoS ONE 9 (5): e92596. 5 May 2014

Oral verabreichbare pharmazeutische Zubereitung umfassend liposomal verkapseltes Taxol [Orally administered pharmaceutical preparation comprising liposomically encapsulated paclitaxel].
Reszka, R. and Fichtner, I.
DE10154464A1 ; DE10154464B4 ; EP1443904 ; WO0339437. 22 May 2003

Response of patient-derived non-small cell lung cancer xenografts to classical and targeted therapies is not related to multidrug resistance markers.
Rolff, J. and Dorn, C. and Merk, J. and Fichtner, I.
Journal of Oncology 2009 : 814140. 2009

In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3.
Ryppa, C. and Mann-Steinberg, H. and Fichtner, I. and Weber, H. and Satchi-Fainaro, R. and Biniossek, M.L. and Kratz, F.
Bioconjugate Chemistry 19 (7): 1414-1422. July 2008

S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells.
Sack, U. and Walther, W. and Scudiero, D. and Selby, M. and Aumann, J. and Lemos, C. and Fichtner, I. and Schlag, P.M. and Shoemaker, R.H. and Stein, U.
Molecular Biology of the Cell 22 (18): 3344-3354. September 2011

Novel effect of antihelminthic niclosamide on S100A4-mediated metastatic progression in colon cancer.
Sack, U. and Walther, W. and Scudiero, D. and Selby, M. and Kobelt, D. and Lemm, M. and Fichtner, I. and Schlag, P.M. and Shoemaker, R.H. and Stein, U.
Journal of the National Cancer Institute 103 (13): 1018-1036. 6 July 2011

Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo.
Schadendorf, D. and Kern, M.A. and Artuc, M. and Pahl, H.L. and Rosenbach, T. and Fichtner, I. and Nuernberg, W. and Stueting, S. and von Stebut, E. and Worm, M. and Makki, A. and Jurgovsky, K. and Kolde, G. and Henz, B.M.
Journal of Cell Biology 135 (6 Pt 2): 1889-1898. December 1996

Antitumor activity of a dual cytokine/single-chain antibody fusion protein for simultaneous delivery of GM-CSF and IL-2 to Ep-CAM expressing tumor cells.
Schanzer, J.M. and Fichtner, I. and Baeuerle, P.A. and Kufer, P.
Journal of Immunotherapy 29 (5): 477-488. September 2006

Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct.
Schlereth, B. and Fichtner, I. and Lorenczewski, G. and Kleindienst, P. and Brischwein, K. and da Silva, A. and Kufer, P. and Lutterbuese, R. and Junghahn, I. and Kasimir-Bauer, S. and Wimberger, P. and Kimmig, R. and Baeuerle, P.A.
Cancer Research 65 : 2882-2889. 1 January 2005

Potent inhibition of local and disseminated tumor growth in immunocompetent mouse models by a bispecific antibody construct specific for Murine CD3.
Schlereth, B. and Kleindienst, P. and Fichtner, I. and Lorenczewski, G. and Brischwein, K. and Lippold, S. and Silva, A.D. and Locher, M. and Kischel, R. and Lutterbuese, R. and Kufer, P. and Baeuerle, P.A.
Cancer Immunology Immunotherapy 55 : 785-796. July 2006

The inhibition of the integrin VLA-4 in MV3 melanoma cell binding by non-anticoagulant heparin derivatives.
Schlesinger, M. and Schmitz, P. and Zeisig, R. and Naggi, A. and Torri, G. and Casu, B. and Bendas, G.
Thrombosis Research 129 (5): 603-610. May 2012

Albumin-Binding Prodrugs of Camptothecin and Doxorubicin with an Ala-Leu-Ala-Leu-Linker That Are Cleaved by Cathepsin B: Synthesis and Antitumor Efficacy.
Schmid, B. and Chung, D.E. and Warnecke, A. and Fichtner, I. and Kratz, F.
Bioconjugate Chemistry 18 (3): 702-716. May 2007

Development of albumin-binding camptothecin prodrugs using a peptide positional scanning library.
Schmid, B. and Warnecke, A. and Fichtner, I. and Jung, M. and Kratz, F.
Bioconjugate Chemistry 18 (6): 1786-1799. November 2007

SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.
Schmid, F. and Wang, Q. and Huska, M.R. and Andrade-Navarro, M.A. and Lemm, M. and Fichtner, I. and Dahlmann, M. and Kobelt, D. and Walther, W. and Smith, J. and Schlag, P.M. and Stein, U.
Oncogene 35 (46): 5942-5952. 17 November 2016

Loss-of-function uORF mutations in human malignancies.
Schulz, J. and Mah, N. and Neuenschwander, M. and Kischka, T. and Ratei, R. and Schlag, P.M. and Castaños-Vélez, E. and Fichtner, I. and Tunn, P.U. and Denkert, C. and Klaas, O. and Berdel, W.E. and von Kries, J.P. and Makalowski, W. and Andrade-Navarro, M.A. and Leutz, A. and Wethmar, K.
Scientific Reports 8 (1): 2395. 5 February 2018

The thalidomide analogue, CC-4047, induces apoptosis signaling and growth arrest in childhood acute lymphoblastic leukemia cells in vitro and in vivo.
Shalapour, S. and Zelmer, A. and Pfau, M. and Moderegger, E. and Costa-Blechschmidt, C. and van Landeghem, F.K. and Taube, T. and Fichtner, I. and Buehrer, C. and Henze, G. and Seeger, K. and Wellmann, S.
Clinical Cancer Research 12 (18): 5526-5532. 15 September 2006

Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver.
Sharma, A.D. and Cantz, T. and Richter, R. and Eckert, K. and Henschler, R. and Wilkens, L. and Jochheim-Richter, A. and Arseniev, L. and Ott, M.
American Journal of Pathology 167 (2): 555-564. 1 August 2005

High prevalence and breast cancer predisposing role of the BLMc.1642 C>T (Q548X) mutation in Russia.
Sokolenko, A.P. and Iyevleva, A.G. and Preobrazhenskaya, E.V. and Mitiushkina, N.V. and Abysheva, S.N. and Suspitsin, E.N. and Kuligina, E.S. and Gorodnova, T.V. and Pfeifer, W. and Togo, A.V. and Turkevich, E.A. and Ivantsov, A.O. and Voskresenskiy, D.V. and Dolmatov, G.D. and Bit-Sava, E.M. and Matsko, D.E. and Semiglazov, V.F. and Fichtner, I. and Larionov, A.A. and Kuznetsov, S.G. and Antoniou, A.C. and Imyanitov, E.N.
International Journal of Cancer 130 (12): 2867-2873. 15 June 2012

Teratoma formation of human embryonic stem cells in three-dimensional perfusion culture bioreactors.
Stachelscheid, H. and Wulf-Goldenberg, A. and Eckert, K. and Jensen, J. and Edsbagge, J. and Bjoerquist, P. and Rivero, M. and Strehl, R. and Jozefczuk, J. and Prigione, A. and Adjaye, J. and Urbaniak, T. and Bussmann, P. and Zeilinger, K. and Gerlach, J.C.
Journal of Tissue Engineering and Regenerative Medicine 7 (9): 729-741. September 2013

Cell differentiation mediated by co-culture of human umbilical cord blood stem cells with murine hepatic cells.
Stecklum, M. and Wulf-Goldenberg, A. and Purfürst, B. and Siegert, A. and Keil, M. and Eckert, K. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 51 (2): 183-191. February 2015

Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis.
Stein, U. and Arlt, F. and Smith, J. and Sack, U. and Herrmann, P. and Walther, W. and Lemm, M. and Fichtner, I. and Shoemaker, R.H. and Schlag, P.M.
Neoplasia 13 (2): 131-144. February 2011

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Stein, U. and Walther, W. and Arlt, F. and Schwabe, H. and Smith, J. and Fichtner, I. and Birchmeier, W. and Schlag, P.M.
Nature Medicine 15 (1): 59-67. January 2009

Complete in vivo reversal of the multidrug resistance phenotype by jet-injection of anti-MDR1 short hairpin RNA-encoding plasmid DNA.
Stein, U. and Walther, W. and Stege, A. and Kaszubiak, A. and Fichtner, I. and Lage, H.
Molecular Therapy 16 (1): 178-186. January 2008

Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer.
Tan, W.L. and Bhattacharya, B. and Loh, M. and Balasubramanian, I. and Akram, M. and Dong, D. and Wong, L. and Thakkar, B. and Salto-Tellez, M. and Soo, R.A. and Fichtner, I. and Iacopetta, B. and Soong, R.
Cancer Biology & Therapy 11 (6): 599-608. 15 March 2011

How perifosine affects liposome-encapsulated drug delivery across a cell barrier.
Testen, A and Podlipec, R and Mravljak, J and Orthmann, A and Sentjurc, M and Zeisig, R and Strancar, J and Koklic, T
Therapeutic Delivery 6 (4): 423-441. April 2015

Enhanced tumorigenicity of fibroblasts transformed with human herpesvirus 8 chemokine receptor vGPCR by successive passage in nude and immunocompetent mice.
Thirunarayanan, N. and Cifire, F. and Fichtner, I. and Posner, S. and Benga, J. and Reiterer, P. and Kremmer, E. and Koelble, K. and Lipp, M.
Oncogene 26 (39): 5702-5712. 23 August 2007

Antitumor efficacy, pharmacokinetic and biodistribution studies of the anticancer peptide CIGB-552 in mouse models.
Vallespi, M.G. and Pimentel, G. and Cabrales-Rico, A. and Garza, J. and Oliva, B. and Mendoza, O. and Gomez, Y. and Basaco, T. and Sanchez, I. and Calderon, C. and Rodriguez, J.C. and Markelova, M.R. and Fichtner, I. and Astrada, S. and Bollati-Fogolín, M. and Garay, H.E. and Reyes, O.
Journal of Peptide Science 20 (11): 850-859. November 2014

Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.
Varvaresou, A. and Iakovou, K. and Gikas, E. and Fichtner, I. and Fiebig, H.H. and Kelland, L.R. and Double, J.A. and Bibby, M.C. and Hendriks, H.R.
Anticancer Research 24 (2): 907-919. March 2004

Heat-inducible in vivo gene therapy of colon carcinoma by human mdr1 promoter-regulated tumor necrosis factor-alpha expression.
Walther, W. and Arlt, F. and Fichtner, I. and Aumann, J. and Stein, U. and Schlag, P.M.
Molecular Cancer Therapeutics 6 (1): 236-243. January 2007

The activity of titanocene T against xenografted Caki-1 tumors.
Walther, W. and Fichtner, I. and Deally, A. and Hogan, M. and Tacke, M.
Letters in Drug Design & Discovery 10 (5): 375-381. June 2013

In vitro and in vivo investigations into the carbene copper bromide anticancer drug candidate WBC4.
Walther, W. and Fichtner, I. and Hackenberg, F. and Streciwilk, W. and Tacke, M.
Letters in Drug Design & Discovery 11 (7): 825-832. August 2014

Nonviral jet-injection technology for intratumoral in vivo gene transfer of naked DNA.
Walther, W. and Fichtner, I. and Schlag, P.M. and Stein, U.S.
Methods in Molecular Biology 542 : 195-208. 2009

Uptake, biodistribution, and time course of naked plasmid DNA trafficking after intratumoral in vivo jet injection.
Walther, W. and Minow, T. and Martin, R. and Fichtner, I. and Schlag, P.M. and Stein, U.
Human Gene Therapy 17 (6): 611-624. 15 June 2006

Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors.
Walther, W. and Petkov, S. and Kuvardina, O.N. and Aumann, J. and Kobelt, D. and Fichtner, I. and Lemm, M. and Piontek, J. and Blasig, I.E. and Stein, U. and Schlag, P.M.
Gene Therapy 19 (5): 494-503. May 2012

A seven-year storage report of good manufacturing practice-grade naked plasmid DNA: stability, topology, and in vitro/in vivo functional analysis.
Walther, W. and Schmeer, M. and Kobelt, D. and Baier, R. and Harder, A. and Walhorn, V. and Anselmetti, D. and Aumann, J. and Fichtner, I. and Schleef, M.
Human Gene Therapy Clinical Development 24 (4): 147-153. December 2013

Nonviral jet-injection gene transfer for efficient in vivo cytosine deaminase suicide gene therapy of colon carcinoma.
Walther, W. and Stein, U. and Fichtner, I. and Kobelt, D. and Aumann, J. and Arlt, F. and Schlag, P.M.
Molecular Therapy 12 (6): 1176-1184. 29 September 2005

Low-volume jet injection for efficient nonviral in vivo gene transfer.
Walther, W. and Stein, U. and Fichtner, I. and Schlag, P.M.
Molecular Biotechnology 28 (2): 121-128. 1 January 2004

Use of the nuclease inhibitor aurintricarboxylic acid (ATA) for improved non-viral intratumoral in vivo gene transfer by jet-injection.
Walther, W. and Stein, U. and Siegel, R. and Fichtner, I. and Schlag, P.M.
Journal of Gene Medicine 7 (4): 477-485. 1 January 2005

Synthesis and biological activity of water-soluble maleimide derivatives of the anticancer drug Carboplatin designed as albumin-binding prodrugs.
Warnecke, A. and Fichtner, I. and Garmann, D. and Jaehde, U. and Kratz, F.
Bioconjugate Chemistry 15 (6): 1349-1359. 1 November 2004

Synthesis, cleavage profile, and antitumor efficacy of an albumin-binding prodrug of methotrexate that is cleaved by plasmin and cathepsin B.
Warnecke, A. and Fichtner, I. and Sass, G. and Kratz, F.
Archiv der Pharmazie 340 (8): 389-395. August 2007

Inhibition of metastasis in a murine 4T1 breast cancer model by liposomes preventing tumor cell-platelet interactions.
Wenzel, J. and Zeisig, R. and Fichtner, I.
Clinical and Experimental Metastasis 27 (1): 25-34. January 2010

Inhibition of breast cancer metastasis by dual liposomes to disturb complex formation.
Wenzel, J. and Zeisig, R. and Fichtner, I.
International Journal of Pharmaceutics 370 (1-2): 121-128. 31 March 2009

Inhibition of pulmonary metastasis in a human MT3 breast cancer xenograft model by dual liposomes preventing intravasal fibrin clot formation.
Wenzel, J. and Zeisig, R. and Haider, W. and Habedank, S. and Fichtner, I.
Breast Cancer Research and Treatment 121 (1): 13-22. May 2010

Molecular mode of action and role of TP53 in the sensitivity to the novel epothilone sagopilone (ZK-EPO) in A549 non-small cell lung cancer cells.
Winsel, S. and Sommer, A. and Eschenbrenner, J. and Mittelstaedt, K. and Klar, U. and Hammer, S. and Hoffmann, J.
PLoS ONE 6 (4): e19273. 29 April 2011

Intrahepatically transplanted human cord blood cells reduce SW480 tumor growth in the presence of bispecific EpCAM/CD3 antibody.
Wulf-Goldenberg, A. and Eckert, K. and Fichtner, I.
Cytotherapy 13 (1): 108-113. January 2011

Cytokine-pretreatment of CD34(+) cord blood stem cells in vitro reduces long-term cell engraftment in NOD/SCID mice.
Wulf-Goldenberg, A. and Eckert, K. and Fichtner, I.
European Journal of Cell Biology 87 (2): 69-80. 14 February 2008

Intrahepatic transplantation of CD34(+) cord blood stem cells into newborn and adult NOD/SCID mice induce differential organ engraftment.
Wulf-Goldenberg, A. and Keil, M. and Fichtner, I. and Eckert, K.
Tissue & Cell 44 (2): 80-86. April 2012

Anti-proliferative efficacy of icariin on HepG2 hepatoma and its possible mechanism of action.
Yang, J.X. and Fichtner, I. and Becker, M. and Lemm, M. and Wang, X.M.
American Journal of Chinese Medicine 37 (6): 1153-1165. 2009

Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT.
Yde, C.W. and Frogne, T. and Lykkesfeldt, A.E. and Fichtner, I. and Issinger, O.G. and Stenvang, J.
Cancer Letters 256 (2): 229-237. 28 October 2007

Physical properties and pharmacological activity in vitro and in vivo of optimised liposomes prepared from a new cancerostatic alkylphospholipid.
Zeisig, R. and Arndt, D. and Stahn, R. and Fichtner, I.
Biochimica et Biophysica Acta - Biomembranes 1414 (1-2): 238-248. 11 November 1998

Increase in fluidity in the membrane of MT3 breast cancer cells correlates with enhanced cell adhesion in vitro and increased lung metastasis in NOD/SCID mice.
Zeisig, R. and Koklic, T. and Wiesner, B. and Fichtner, I. and Sentjurc, M.
Archives of Biochemistry and Biophysics 459 (1): 98-106. 1 March 2007

Lipoplexes with alkylphospholipid as new helper lipid for efficient in vitro and in vivo gene transfer in tumor therapy.
Zeisig, R. and Ress, A. and Fichtner, I. and Walther, W.
Cancer Gene Therapy 10 (4): 302-311. April 2003

Reduction of tamoxifen resistance in human breast carcinomas by tamoxifen-containing liposomes in vivo.
Zeisig, R. and Rueckerl, D. and Fichtner, I.
Anti-Cancer Drugs 15 (7): 707-714. 1 August 2004

Effect of sialyl Lewis X-glycoliposomes on the inhibition of E-selectin-mediated tumour cell adhesion in vitro.
Zeisig, R. and Stahn, R. and Wenzel, K. and Behrens, D. and Fichtner, I.
Biochimica et Biophysica Acta - Biomembranes 1660 (1): 31-40. 28 January 2004

Liposomal 4-hydroxy-tamoxifen: effect on cellular uptake and resulting cytotoxicity in drug resistant breast cancer cells in vitro.
Zeisig, R. and Teppke, A.D. and Behrens, D. and Fichtner, I.
Breast Cancer Research and Treatment 87 (3): 245-254. 1 January 2004

Fielitz, Jens (ECRC)

The short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H. and Balogh, A. and Yakoub, M. and Homann, S. and Markó, L. and Höges, S. and Tsvetkov, D. and Krannich, A. and Wundersitz, S. and Avery, E.G. and Haase, N. and Kräker, K. and Hering, L. and Maase, M. and Kusche-Vihrog, K. and Grandoch, M. and Fielitz, J. and Kempa, S. and Gollasch, M. and Zhumadilov, Z. and Kozhakhmetov, S. and Kushugulova, A. and Eckardt, K.U. and Dechend, R. and Rump, L.C. and Forslund, S.K. and Müller, D.N. and Stegbauer, J. and Wilck, N.
Circulation 139 (11): 1407-1421. 12 March 2019

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M. and Yu, Y. and Liang, L. and Vuralli, D. and Froehler, S. and Kuehnen, P. and Du Bois, P. and Zhang, J. and Cao, A. and Liu, Y. and Hussain, K. and Fielitz, J. and Jia, S. and Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7 (5): e602. May 2019

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D. and Pahuja, A. and Geers-Knörr, C. and Scheibe, R. and Nowak, M. and Hamati, J. and Köhncke, C. and Purfürst, B. and Kanashova, T. and Schmidt, S. and Glass, D.J. and Morano, I. and Heuser, A. and Kraft, T. and Bassel-Duby, R. and Olson, E.N. and Dittmar, G. and Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180. May 2016

Fischer, Christian (ECRC)

Axon guidance factor Slit2 inhibits neural invasion and metastasis in pancreatic cancer.
Goehrig, A. and Detjen, K.M. and Hilfenhaus, G. and Koerner, J. and Welzel, M. and Arsenic, R. and Schmuck, R. and Bahra, M. and Wu, J.Y. and Wiedenmann, B. and Fischer, C.
Cancer Research 74 (5): 1529-1540. 1 March 2014

Morphological analysis and differentiation of benign cystic neoplasms of the pancreas using computed tomography and magnetic resonance imaging.
Grieser, C. and Heine, G. and Stelter, L. and Steffen, I.G. and Rothe, J.H. and Walter, T.C. and Fischer, C. and Bahra, M. and Denecke, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 185 (3): 219-227. March 2013

Forslund, Sofia (MDC/ECRC)

The short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H. and Balogh, A. and Yakoub, M. and Homann, S. and Markó, L. and Höges, S. and Tsvetkov, D. and Krannich, A. and Wundersitz, S. and Avery, E.G. and Haase, N. and Kräker, K. and Hering, L. and Maase, M. and Kusche-Vihrog, K. and Grandoch, M. and Fielitz, J. and Kempa, S. and Gollasch, M. and Zhumadilov, Z. and Kozhakhmetov, S. and Kushugulova, A. and Eckardt, K.U. and Dechend, R. and Rump, L.C. and Forslund, S.K. and Müller, D.N. and Stegbauer, J. and Wilck, N.
Circulation 139 (11): 1407-1421. 12 March 2019

Ganten, Detlev

Monogen bedingte Erbkrankheiten 1.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 6 . Springer, Berlin [u.a.]. ISBN 3-540-65529-8 1 January 2000

Monogen bedingte Erbkrankheiten 2.
Ganten, D. and Ruckpaul, K.
Handbuch der Molekularen Medizin ; 7 . Springer, Berlin [u.a.]. ISBN 3-540-65530-1 1 January 2000

Evolutionary molecular medicine.
Nesse, R.M. and Ganten, D. and Gregory, T.R. and Omenn, G.S.
Journal of Molecular Medicine 90 (5): 509-522. May 2012

Gargiulo, Gaetano

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Bracken, A.P. and Kleine-Kohlbrecher, D. and Dietrich, N. and Pasini, D. and Gargiulo, G. and Beekman, C. and Theilgaard-Moench, K. and Minucci, S. and Porse, B.T. and Marine, J.-C. and Hansen, K.H. and Helin, K.
Genes & Development 21 (5): 525-530. 1 March 2007

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.
Di Micco, R. and Sulli, G. and Dobreva, M. and Liontos, M. and Botrugno, O.A. and Gargiulo, G. and dal Zuffu, R. and Matti, V. and d'Ario, G. and Montani, E. and Mercurio, C. and Hahn, W.C. and Gorgoulis, V. and Minucci, S. and d'Adda di Fagagna, F.
Nature Cell Biology 13 (3): 292-302. March 2011

SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin.
Ferone, G. and Song, J.Y. and Sutherland, K.D. and Bhaskaran, R. and Monkhorst, K. and Lambooij, J.P. and Proost, N. and Gargiulo, G. and Berns, A.
Cancer Cell 30 (4): 519-532. 10 October 2016

Next-Generation in vivo modeling of human cancers.
Gargiulo, G.
Frontiers in Oncology 8 : 429. October 2018

In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.
Gargiulo, G. and Cesaroni, M. and Serresi, M. and de Vries, N. and Hulsman, D. and Bruggeman, S.W. and Lancini, C. and van Lohuizen, M.
Cancer Cell 23 (5): 660-676. 13 May 2013

Polycomb and lung cancer: when the dosage makes the (kind of) poison.
Gargiulo, G. and Citterio, E. and Serresi, M.
Molecular & Cellular Oncology 3 (3): e1152345. May 2016

NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation.
Gargiulo, G. and Levy, S. and Bucci, G. and Romanenghi, M. and Fornasari, L. and Beeson, K.Y. and Goldberg, S.M. and Cesaroni, M. and Ballarini, M. and Santoro, F. and Bezman, N. and Frige, G. and Gregory, P.D. and Holmes, M.C. and Strausberg, R.L. and Pelicci, P.G. and Urnov, F.D. and Minucci, S.
Developmental Cell 16 (3): 466-481. 17 March 2009

Epigenomic profiling of cancer cells.
Gargiulo, G. and Minucci, S.
International Journal of Biochemistry and Cell Biology 41 (1): 127-135. January 2009

In vivo shRNA screens in solid tumors.
Gargiulo, G. and Serresi, M. and Cesaroni, M. and Hulsman, D. and van Lohuizen, M.
Nature Protocols 9 (12): 2880-2902. December 2014

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.
Lancini, C. and van den Berk, P.C.M. and Vissers, J.H.A. and Gargiulo, G. and Song, J.Y. and Hulsman, D. and Serresi, M. and Tanger, E. and Blom, M. and Vens, C. and van Lohuizen, M. and Jacobs, H. and Citterio, E.
Journal of Experimental Medicine 211 (9): 1759-1777. 25 August 2014

Targeting APLN/APLNR improves antiangiogenic efficiency and blunts proinvasive side effects of VEGFA/VEGFR2 blockade in glioblastoma.
Mastrella, G. and Hou, M. and Li, M. and Stoecklein, V.M. and Zdouc, N. and Volmar, M.N.M. and Miletic, H. and Reinhard, S. and Herold-Mende, C.C. and Kleber, S. and Eisenhut, K. and Gargiulo, G. and Synowitz, M. and Vescovi, A.L. and Harter, P.N. and Penninger, J.M. and Wagner, E. and Mittelbronn, M. and Bjerkvig, R. and Hambardzumyan, D. and Schüller, U. and Tonn, J.C. and Radke, J. and Glass, R. and Kälin, R.E.
Cancer Research 79 (9): 2298-2313. May 2019

Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epithelial-mesenchymal transition in non-small-cell lung cancer.
Serresi, M. and Gargiulo, G. and Proost, N. and Siteur, B. and Cesaroni, M. and Koppens, M. and Xie, H. and Sutherland, K.D. and Hulsman, D. and Citterio, E. and Orkin, S. and Berns, A. and van Lohuizen, M.
Cancer Cell 29 (1): 17-31. 11 January 2016

Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Serresi, M. and Siteur, B. and Hulsman, D. and Company, C. and Schmitt, M.J. and Lieftink, C. and Morris, B. and Cesaroni, M. and Proost, N. and Beijersbergen, R.L. and van Lohuizen, M. and Gargiulo, G.
Journal of Experimental Medicine 215 (12): 3115. 3 December 2018

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.
Sparmann, A. and Xie, Y. and Verhoeven, E. and Vermeulen, M. and Lancini, C. and Gargiulo, G. and Hulsman, D. and Mann, M. and Knoblich, J.A. and van Lohuizen, M.
EMBO Journal 32 (11): 1598-1612. 29 May 2013

Garratt, Alistair N.

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Geier, Christian (ECRC)

Subacute coronary stent thrombosis in cancer patients.
Gross, C.M. and Posch, M.G. and Geier, C. and Olthoff, H. and Kraemer, J. and Dechend, R. and Dietz, R. and Oezcelik, C.
Journal of the American College of Cardiology 51 (12): 1232-1233. 25 March 2008

Gerhardt, Holger

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. and Friese, C. and Arina, A. and Idel, C. and Briesemeister, D. and Rothe, M. and Ivanov, A. and Szymborska, A. and Patone, G. and Kunz, S. and Sommermeyer, D. and Engels, B. and Leisegang, M. and Textor, A. and Fehling, H.J. and Fruttiger, M. and Lohoff, M. and Herrmann, A. and Yu, H. and Weichselbaum, R. and Uckert, W. and Hübner, N. and Gerhardt, H. and Beule, D. and Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. and Kirchner, M. and Uyar, B. and Cheng, J.Y. and Russo, G. and Hernandez-Miranda, L.R. and Szymborska, A. and Zauber, H. and Rudolph, I.M. and Willnow, T.E. and Akalin, A. and Haucke, V. and Gerhardt, H. and Birchmeier, C. and Kühn, R. and Krauss, M. and Diecke, S. and Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm, K. and Happel, K. and Eelen, G. and Schoors, S. and Oellerich, M.F. and Lim, R. and Zimmermann, B. and Aspalter, I.M. and Franco, C.A. and Boettger, T. and Braun, T. and Fruttiger, M. and Rajewsky, K. and Keller, C. and Brüning, J.C. and Gerhardt, H. and Carmeliet, P. and Potente, M.
Nature 529 (7585): 216-220. 14 January 2016

Gerull, Brenda

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B. and Heuser, A. and Wichter, T. and Paul, M. and Basson, C.T. and McDermott, D.A. and Lerman, B.B. and Markowitz, S.M. and Ellinor, P.T. and MacRae, C.A. and Peters, S. and Grossmann, K.S. and Drenckhahn, J. and Michely, B. and Sasse-Klaassen, S. and Birchmeier, W. and Dietz, R. and Breithardt, G. and Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36 (11): 1162-1164. November 2004

Gollasch, Maik (ECRC)

The short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H. and Balogh, A. and Yakoub, M. and Homann, S. and Markó, L. and Höges, S. and Tsvetkov, D. and Krannich, A. and Wundersitz, S. and Avery, E.G. and Haase, N. and Kräker, K. and Hering, L. and Maase, M. and Kusche-Vihrog, K. and Grandoch, M. and Fielitz, J. and Kempa, S. and Gollasch, M. and Zhumadilov, Z. and Kozhakhmetov, S. and Kushugulova, A. and Eckardt, K.U. and Dechend, R. and Rump, L.C. and Forslund, S.K. and Müller, D.N. and Stegbauer, J. and Wilck, N.
Circulation 139 (11): 1407-1421. 12 March 2019

Gossen, Manfred

Binding of Drosophila ORC proteins to anaphase chromosomes requires cessation of mitotic cyclin-dependent kinase activity.
Baldinger, T. and Gossen, M.
Molecular and Cellular Biology 29 (1): 140-149. January 2009

Co-regulation of two gene activities by tetracycline via a bidirectional promoter.
Baron, U. and Freundlieb, S. and Gossen, M. and Bujard, H.
Nucleic Acids Research 23 (17): 3605-3606. 11 September 1995

Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential.
Baron, U. and Gossen, M. and Bujard, H.
Nucleic Acids Research 25 (14): 2723-2729. 15 July 1997

Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR).
Fitze, G. and Appelt, H. and Koenig, I.R. and Goergens, H. and Stein, U. and Walther, W. and Gossen, M. and Schreiber, M. and Ziegler, A. and Roesner, D. and Schackert, H.K.
Human Molecular Genetics 12 (24): 3207-3214. 1 January 2003

Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells.
Gossen, M. and Bujard, H.
Nucleic Acids Research 21 (18): 4411-4412. 11 September 1993

Conditional gene expression: Intelligent designs.
Gossen, M.
Gene Therapy 13 (17): 1251-1252. September 2006

Promoter crosstalk effects on gene expression.
Hampf, M. and Gossen, M.
Journal of Molecular Biology 365 (4): 911-920. 26 January 2007

A protocol for combined Photinus and Renilla luciferase quantification compatible with protein assays.
Hampf, M. and Gossen, M.
Analytical Biochemistry 356 (1): 94-99. 1 September 2006

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.
Kaufman, W.L. and Kocman, I. and Agrawal, V. and Rahn, H.P. and Besser, D. and Gossen, M.
Nucleic Acids Research 36 (17): e111. October 2008

Stability and homogeneity of transgene expression in isogenic cells.
Liu, W. and Xiong, Y. and Gossen, M.
Journal of Molecular Medicine 84 (1): 57-64. January 2006

A structural role for ATP in the formation and stability of the human origin recognition complex.
Ranjan, A. and Gossen, M.
Proceedings of the National Academy of Sciences of the United States of America 103 (13): 4864-4869. 28 March 2006

The power of reversibility regulating gene activities via tetracycline-controlled transcription.
Schoenig, K. and Bujard, H. and Gossen, M.
Methods in Enzymology 477 (C): 429-453. 2010

Development of a BAC vector for integration-independent and tight regulation of transgenes in rodents via the Tet system.
Schoenig, K. and Kentner, D. and Gossen, M. and Baldinger, T. and Miao, J. and Welzel, K. and Vente, A. and Bartsch, D. and Bujard, H.
Transgenic Research 20 (3): 709-720. June 2011

Characterization of apoptosis-induced Mcm3 and Cdc6 cleavage reveals a proapoptotic effect for one Mcm3 fragment.
Schories, B. and Engel, K. and Doerken, B. and Gossen, M. and Bommert, K.
Cell Death and Differentiation 11 (8): 940-942. August 2004

Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8+ T cells.
Schueler, T. and Kammertoens, T. and Preiss, S. and Debs, P. and Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 194 (12): 1767-1775. 17 December 2001

Global analysis of cellular protein translation by pulsed SILAC.
Schwanhaeusser, B. and Gossen, M. and Dittmar, G. and Selbach, M.
Proteomics 9 (1): 205-209. January 2009

Prevalence of primary hyperaldosteronism in moderate to severe hypertension in the Central Europe region.
Strauch, B. and Zelinka, T. and Hampf, M. and Bernhardt, R. and Widimsky, J.
Journal of Human Hypertension 17 (5): 349-352. May 2003

Different roles of the human Orc6 protein in the replication initiation process.
Thomae, A.W. and Baltin, J. and Pich, D. and Deutsch, M.J. and Ravasz, M. and Zeller, K. and Gossen, M. and Hammerschmidt, W. and Schepers, A.
Cellular and Molecular Life Sciences 68 (22): 3741-3756. November 2011

Inducible expression of coding and inhibitory RNAs from retargetable genomic loci.
Weidenfeld, I. and Gossen, M. and Loew, R. and Kentner, D. and Berger, S. and Goerlich, D. and Bartsch, D. and Bujard, H. and Schoenig, K.
Nucleic Acids Research 37 (7): e50. April 2009

Gotthardt, Michael

Expanding the map of protein-RNA interaction sites via cell fusion followed by PAR-CLIP.
Hinze, F. and Drewe-Boss, P. and Milek, M. and Ohler, U. and Landthaler, M. and Gotthardt, M.
RNA Biology 15 (3): 359-368. 4 March 2018

SURF1 mutations causative of Leigh syndrome impair human neurogenesis.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Juettner, R. and Zink, A. and Mlody, B. and Glazar, P. and Secker, C. and Ciptasari, U.H. and Stenzel, W. and Hahn, T. and Diecke, S. and Priller, J. and Gotthardt, M. and Kuehn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
bioRxiv : 551390. 20 February 2019

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.
Park, T.J. and Reznick, J. and Peterson, B.L. and Blass, G. and Omerbašić, D. and Bennett, N.C. and Kuich, P.H.J.L. and Zasada, C. and Browe, B.M. and Hamann, W. and Applegate, D.T. and Radke, M.H. and Kosten, T. and Lutermann, H. and Gavaghan, V. and Eigenbrod, O. and Bégay, V. and Amoroso, V. G. and Govind, V. and Minshall, R.D. and Smith, E.S.J. and Larson, J. and Gotthardt, M. and Kempa, S. and Lewin, G.R.
Science 356 (6335): 307-311. 21 April 2017

Hammes-Lewin, Annette

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. and Czajkowski, M.T. and Barth, C. and Müller, P.M. and McShane, E. and Grunwald, S. and Beaudette, P. and Mecklenburg, N. and Volkmer, R. and Zühlke, K. and Dittmar, G. and Selbach, M. and Hammes, A. and Daumke, O. and Klussmann, E. and Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Heinemann, Udo

An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.
Andres, D. and Gohlke, U. and Broeker, N.K. and Schulze, S. and Rabsch, W. and Heinemann, U. and Barbirz, S. and Seckler, R.
Glycobiology 23 (4): 486-494. April 2013

Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system.
Andresen, D. and Roske, Y. and Doering, C. and Heinemann, U. and Seckler, R. and Barbirz, S.
Molecular Microbiology 83 (6): 1244-1253. March 2012

Eukaryotic expression: developments for structural proteomics.
Aricescu, A.R. and Assenberg, R. and Bill, R.M. and Busso, D. and Chang, V.T. and Davis, S.J. and Dubrovsky, A. and Gustafsson, L. and Hedfalk, K. and Heinemann, U. and Jones, I.M. and Ksiazek, D. and Lang, C. and Maskos, K. and Messerschmidt, A. and Macieira, S. and Peleg, Y. and Perrakis, A. and Poterszman, A. and Schneider, G. and Sixma, T.K. and Sussman, J.L. and Sutton, G. and Tarboureich, N. and Zeev-Ben-Mordehai, T. and Jones, E.Y.
Acta Crystallographica Section D 62 (Pt. 10): 1114-1124. October 2006

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A. and Roske, Y. and Barth, C. and Lleras Forero, L. and Bravo-Rodriguez, K. and Redel, Al. and Kostova, S. and McShane, E. and Opitz, R. and Faelber, K. and Rau, K. and Mielke, T. and Daumke, O. and Selbach, M. and Sanchez-Garcia, E. and Rocks, O. and Panáková, D. and Heinemann, U. and Wanker, E.E.
Nature Communications 7 : 13047. 20 October 2016

Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.
Ash, M.R. and Faelber, K. and Kosslick, D. and Albert, G.I. and Roske, Y. and Kofler, M. and Schuemann, M. and Krause, E. and Freund, C.
Structure 18 (8): 944-954. 11 August 2010

Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol.
Avvakumov, G.V. and Grishkovskaya, I. and Muller, Y.A. and Hammond, G.L.
Journal of Biological Chemistry 277 (47): 45219-45225. 22 November 2002

Structure and function of the Bacillus hybrid enzyme GluXyn-1: Native-like jellyroll fold preserved after insertion of autonomous globular domain.
Ay, J. and Goetz, F. and Borriss, R. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 95 (12): 6613-6618. 9 June 1998

Structural proteomics: from the molecule to the system.
Banci, L. and Baumeister, W. and Enfedaque, J. and Heinemann, U. and Schneider, G. and Silman, I. and Sussman, J.L.
Nature Structural & Molecular Biology 14 (1): 3-4. January 2007

An idea whose time has come.
Banci, L. and Baumeister, W. and Heinemann, U. and Schneider, G. and Silman, I. and Stuart, D.I. and Sussman, J.L.
Genome Biology 8 (11): 408. 7 November 2007

First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.
Banci, L. and Bertini, I. and Cusack, S. and de Jong, R.N. and Heinemann, U. and Jones, E.Y. and Kozielski, F. and Maskos, K. and Messerschmidt, A. and Owens, R. and Perrakis, A. and Poterszman, A. and Schneider, G. and Siebold, C. and Silman, I. and Sixma, T. and Stewart-Jones, G. and Sussman, J.L. and Thierry, J.C. and Moras, D.
Acta Crystallographica Section D 62 (Pt. 10): 1208-1217. October 2006

Crystal structure of Escherichia coli phage HK620 tailspike: podoviral tailspike endoglycosidase modules are evolutionarily related.
Barbirz, S. and Mueller, J.J. and Uetrecht, C. and Clark, A.J. and Heinemann, U. and Seckler, R.
Molecular Microbiology 69 (2): 303-316. July 2008

Structural identification of the VPS18 β-propeller reveals a critical role in the HOPS complex stability and function.
Behrmann, H. and Lürick, A. and Kuhlee, A. and Kleine Balderhaar, H. and Bröcker, C. and Kümmel, D. and Engelbrecht-Vandré, S. and Gohlke, U. and Raunser, S. and Heinemann, U. and Ungermann, C.
Journal of Biological Chemistry 289 (48): 33503-33512. 28 November 2014

Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues.
Benndorf, R. and Gilmont, R.R. and Hirano, S. and Ransom, R.F. and Jungblut, P.R. and Bommer, M. and Goldman, J.E. and Welsh, M.J.
Cell Stress & Chaperones 23 (5): 813-826. September 2018

Conformation and stability of the Streptococcus pyogenes pSM19035-encoded site-specific beta recombinase, and identification of a folding intermediate.
Bhardwaj, A. and Welfle, K. and Misselwitz, R. and Ayora, S. and Alonso, J.C. and Welfle, H.
Biological Chemistry 387 (5): 525-533. May 2006

Crystal structure of NblA from Anabaena sp. PCC 7120, a small protein playing a key role in phycobilisome degradation.
Bienert, R. and Baier, K. and Volkmer, R. and Lockau, W. and Heinemann, U.
Journal of Biological Chemistry 281 (8): 5216-5223. 24 February 2006

Single-stranded DNA bound to bacterial cold-shock proteins: preliminary crystallographic and Raman analysis.
Bienert, R. and Zeeb, M. and Dostal, L. and Feske, A. and Magg, C. and Max, K. and Welfle, H. and Balbach, J. and Heinemann, U.
Acta Crystallographica Section D 60 (4): 755-757. 1 January 2004

Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme.
Boehm, K. and Herter, T. and Mueller, J.J. and Borriss, R. and Heinemann, U.
FEBS Journal 277 (5): 1284-1296. March 2010

Single amino acid exchange in bacteriophage HK620 tailspike protein results in thousand-fold increase of its oligosaccharide affinity.
Broeker, N.K. and Gohlke, U. and Müller, J.J. and Uetrecht, C. and Heinemann, U. and Seckler, R. and Barbirz, S.
Glycobiology 23 (1): 59-68. January 2013

Time-resolved DNA release from an O-antigen specific Salmonella bacteriophage with a contractile tail.
Broeker, N.K. and Roske, Y. and Valleriani, A. and Stephan, M.S. and Andres, D. and Koetz, J. and Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 12 June 2019 (In Press)

Expression of protein complexes using multiple E. coli protein co-expression systems: a benchmarking study.
Busso, D. and Peleg, Y. and Heidebrecht, T. and Romier, C. and Jacobovitch, Y. and Dantes, A. and Salim, L. and Troesch, E. and Schuetz, A. and Heinemann, U. and Folkers, G.E. and Geerlof, A. and Wilmanns, M. and Polewacz, A. and Quedenau, C. and Büssow, K. and Adamson, R. and Blagova, E. and Walton, J. and Cartwright, J.L. and Bird, L.E. and Owens, R.J. and Berrow, N.S. and Wilson, K.S. and Sussman, J.L. and Perrakis, A. and Celie, P.H.
Journal of Structural Biology 175 (2): 159-170. August 2011

Identification of a novel benzimidazole pyrazolone scaffold that inhibits KDM4 lysine demethylases and reduces proliferation of prostate cancer cells.
Carter, D.M. and Specker, E. and Przygodda, J. and Neuenschwander, M. and von Kries, J.P. and Heinemann, U. and Nazaré, M. and Gohlke, U.
SLAS Discovery 22 (7): 801-812. 1 August 2017

Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.
Chevelkov, V. and Faelber, K. and Diehl, A. and Heinemann, U. and Oschkinat, H. and Reif, B.
Journal of Biomolecular NMR 31 (4): 295-310. 1 January 2005

Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Consentius, P. and Gohlke, U. and Loll, B. and Alings, C. and Heinemann, U. and Wahl, M.C. and Risse, T.
Physical Chemistry Chemical Physics 19 (31): 20723-20734. 9 August 2017

Tracking transient conformational states of T4 lysozyme at room temperature combining X-ray crystallography and site-directed spin labeling.
Consentius, P. and Gohlke, U. and Loll, B. and Alings, C. and Mueller, R. and Heinemann, U. and Kaupp, M. and Wahl, M. and Risse, T.
Journal of the American Chemical Society 138 (39): 12868-12875. 5 October 2016

Internal dynamics of the 3-pyrroline-N-oxide ring in spin-labeled proteins.
Consentius, P. and Loll, B. and Gohlke, U. and Alings, C. and Müller, C. and Müller, R. and Teutloff, C. and Heinemann, U. and Kaupp, M. and Wahl, M.C. and Risse, T.
Journal of Physical Chemistry Letters 8 (6): 1113-1117. 16 March 2017

Thermostabilitaet und funktionelle Vielfalt ubiquitaerer Proteinfaltungsdomaenen [Thermostability and functional diversity of ubiquitous protein domains].
Delbrueck, H.
UNSPECIFIED thesis, UNSPECIFIED. 20 September 2002

Structural changes of TasA in biofilm formation of Bacillus subtilis.
Diehl, A. and Roske, Y. and Ball, L. and Chowdhury, A. and Hiller, M. and Molière, N. and Kramer, R. and Stöppler, D. and Worth, C.L. and Schlegel, B. and Leidert, M. and Cremer, N. and Erdmann, N. and Lopez, D. and Stephanowitz, H. and Krause, E. and van Rossum, B.J. and Schmieder, P. and Heinemann, U. and Turgay, K. and Akbey, Ü. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 115 (13): 3237-3242. 27 March 2018

RP4 repressor protein KorB binds to the major groove of the operator DNA: A Raman study.
Dostal, L. and Khare, D. and Bok, J. and Heinemann, U. and Lanka, E. and Welfle, H.
Biochemistry 42 (49): 14476-14482. 1 January 2003

Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif.
Engel, K. and Schultz, H. and Martin, F. and Kotlyarov, A. and Plath, K. and Hahn, M. and Heinemann, U. and Gaestel, M.
Journal of Biological Chemistry 270 (45): 27213-27221. 10 November 1995

Conformation of d (GGGATCCC) 2 in crystals and in solution studied by X-ray diffraction, Raman spectroscopy and molecular modelling.
Fabian, H. and Hoelzer, W. and Heinemann, U. and Sklenar, H. and Welfle, H.
Nucleic Acids Research 21 (3): 569-576. 11 February 1993

Crystal structure of nucleotide-free dynamin.
Faelber, K. and Posor, Y. and Gao, S. and Held, M. and Roske, Y. and Schulze, D. and Haucke, V. and Noe, F. and Daumke, O.
Nature 477 (7366): 556-560. 29 September 2011

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.
Frese, S. and Schubert, W.D. and Findeis, A.C. and Marquardt, T. and Roske, Y.S. and Stradal, T.E. and Heinz, D.W.
Journal of Biological Chemistry 281 (26): 18236-18245. 30 June 2006

Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.
Gaiser, O.J. and Ball, L.J. and Schmieder, P. and Leitner, D. and Strauss, H. and Wahl, M. and Kuehne, R. and Oschkinat, H. and Heinemann, U.
Biochemistry 43 (51): 15983-15995. 1 January 2004

1H, 13C and 15N resonance assignments of the C-terminal BRCT domain from human BRCA1.
Gaiser, O.J. and Oschkinat, H. and Heinemann, U. and Ball, L.J.
Journal of Biomolecular NMR 30 (2): 221-222. 1 January 2004

Structural basis for the substrate specificity of a Bacillus 1,3-1,4-beta-glucanase.
Gaiser, O.J. and Piotukh, K. and Ponnuswamy, W.N. and Planas, A. and Borriss, R. and Heinemann, U.
Journal of Molecular Biology 357 (4): 1211-1225. 7 April 2006

A novel form of RNA double helix based on G·U and C·A(+) wobble base pairing.
Garg, A. and Heinemann, U.
RNA 24 (2): 209-218. February 2018

Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.
Graf, R. and Munschauer, M. and Mastrobuoni, G. and Mayr, F. and Heinemann, U. and Kempa, S. and Rajewsky, N. and Landthaler, M.
RNA Biology 10 (7): 1146-1159. 1 July 2013

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S. and Eckert, C. and Arkona, C. and Radetzki, S. and Böhm, K. and Heinemann, U. and Wolber, G. and von Kries, J.P. and Birchmeier, W. and Rademann, J.
ChemMedChem 10 (5): 815-826. May 2015

Protein production and purification.
Gräslund, S. and Nordlund, P. and Weigelt, J. and Hallberg, M. and Bray, J. and Gileadi, O. and Knapp, S. and Oppermann, U. and Arrowsmith, C. and Hui, R. and Ming, J. and dhe-Paganon, S. and Park, H.W. and Savchenko, A. and Yee, A. and Edwards, A. and Vincentelli, R. and Cambillau, C. and Kim, R. and Kim, S.H. and Rao, Z. and Shi, Y. and Terwilliger, T.C. and Kim, C.Y. and Hung, L.W. and Waldo, G.S. and Peleg, Y. and Albeck, S. and Unger, T. and Dym, O. and Prilusky, J. and Sussman, J.L. and Stevens, R.C. and Lesley, S.A. and Wilson, I.A. and Joachimiak, A. and Collart, F. and Dementieva, I. and Donnelly, M.I. and Eschenfeldt, W.H. and Kim, Y.M. and Stols, L. and Wu, R. and Zhou, M. and Burley, S.K. and Emtage, J.S. and Sauder, J.M. and Thompson, D. and Bain, K. and Luz, J. and Gheyi, T. and Zhang, F. and Atwell, S. and Almo, S.C. and Bonanno, J.B. and Fiser, A. and Swaminathan, S. and Studier, F.W. and Chance, M.R. and Sali, A. and Acton, T.B. and Xiao, R. and Zhao, L. and Ma, L.C. and Hunt, J.F. and Tong, L. and Cunningham, K. and Inouye, M. and Anderson, S. and Janjua, H. and Shastry, R. and Ho, C.K. and Wang, D. and Wang, H. and Jiang, M. and Montelione, G.T. and Stuart, D.I. and Owens, R.J. and Daenke, S. and Schütz, A. and Heinemann, U. and Yokoyama, S. and Büssow, K. and Gunsalus, K.C.
Nature Methods 5 (2): 135-146. February 2008

Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Guenther, S. and Schlundt, A. and Sticht, J. and Roske, Y. and Heinemann, U. and Wiesmueller, K.H. and Jung, G. and Falk, K. and Roetzschke, O. and Freund, C.
Proceedings of the National Academy of Sciences of the United States of America 107 (51): 22219-22224. 21 December 2010

Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease.
Guenther, U.P. and Handoko, L. and Varon, R. and Stephani, U. and Tsao, C.Y. and Mendell, J.R. and Lützkendorf, S. and Hübner, C. and von Au, K. and Jablonka, S. and Dittmar, G. and Heinemann, U. and Schuetz, A. and Schuelke, M.
Journal of Molecular Medicine 87 (1): 31-41. January 2009

AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Götz, F. and Roske, Y. and Schulz, M.S. and Autenrieth, K. and Bertinetti, D. and Faelber, K. and Zühlke, K. and Kreuchwig, A. and Kennedy, E. and Krause, G. and Daumke, O. and Herberg, F.W. and Heinemann, U. and Klussmann, E.
Biochemical Journal 473 (13): 1881-1894. 28 June 2016

Crystal structure and site-directed mutagenesis of Bacillus macerans endo-1,3-1,4-beta-glucanase.
Hahn, M. and Olsen, O. and Politz, O. and Borriss, R. and Heinemann, U.
Journal of Biological Chemistry 270 (7): 3081-3088. 17 February 1995

Light-induced reduction of bovine adrenodoxin via the covalently bound ruthenium(II) bipyridyl complex: Intramolecular electron transfer and crystal structure.
Halavaty, A. and Mueller, J.J. and Contzen, J. and Jung, C. and Hannemann, F. and Bernhardt, R. and Galander, M. and Lendzian, F. and Heinemann, U.
Biochemistry 45 (3): 709-718. 24 January 2006

Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
Hanna, J. and Schütz, A. and Zimmermann, F. and Behlke, J. and Sommer, T. and Heinemann, U.
Journal of Biological Chemistry 287 (11): 8633-8640. 9 March 2012

The dipole moment of the electron carrier adrenodoxin is not critical for redox partner interaction and electron transfer.
Hannemann, F. and Guyot, A. and Zoellner, A. and Mueller, J.J. and Heinemann, U. and Bernhardt, R.
Journal of Inorganic Biochemistry 103 (7): 997-1004. July 2009

Structural genomics: structure-to-function approaches.
Heinemann, U.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1810-1816. ISBN 3-540-44244-8 2006

Facilities and methods for the high-throughput crystal structural analysis of human proteins.
Heinemann, U. and Buessow, K. and Mueller, U. and Umbach, P.
Accounts of Chemical Research 36 (3): 157-163. March 2003

Establishing a structural genomics platform: The Berlin-based Protein Structure Factory.
Heinemann, U.
Gene Function and Disease 3 (1-2): 25-32. October 2002

The Berlin "protein structure factory" initiative: a technology-oriented approach to structural genomics.
Heinemann, U.
Ernst Schering Research Foundation Workshop 34 : 101-121. 2001

The interaction domain of the redox protein adrenodoxin is mandatory for binding of the electron acceptor CYP11A1, but is not required for binding of the electron donor adrenodoxin reductase.
Heinz, A. and Hannemann, F. and Mueller, J.J. and Heinemann, U. and Bernhardt, R.
Biochemical and Biophysical Research Communications 338 (9): 491-498. 29 August 2005

Building functional modules from molecular interactions.
Hofmann, K.P. and Spahn, C.M.T. and Heinrich, R. and Heinemann, U.
Trends in Biochemical Sciences 31 (9): 497-508. September 2006

Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.
Horatscheck, A. and Wagner, S. and Ortwein, J. and Kim, B.G. and Lisurek, M. and Beligny, S. and Schuetz, A. and Rademann, J.
Angewandte Chemie International Edition 51 (37): 9441-9447. 10 September 2012

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C. and Hanna, J. and Hirsch, C. and Volkwein, C. and Schütz, A. and Heinemann, U. and Sommer, T. and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009

Tricellulin is a target of the ubiquitin ligase Itch.
Jennek, S. and Mittag, S. and Reiche, J. and Westphal, J.K. and Seelk, S. and Dörfel, M.J. and Pfirrmann, T. and Friedrich, K. and Schütz, A. and Heinemann, U. and Huber, O.
Annals of the New York Academy of Sciences 1397 (1): 157-168. June 2017

Crystal structures of the single PDZ domains from GRASP65 and their interaction with the golgin GM130.
Jurk, C.M. and Roske, Y. and Heinemann, U.
Croatica Chemica Acta 91 (2): 255-264. June 2018

Bacteriophage tailspikes and bacterial O-antigens as a model system to study weak-affinity protein-polysaccharide interactions.
Kang, Y. and Gohlke, U. and Engström, O. and Hamark, C. and Scheidt, T. and Kunstmann, S. and Heinemann, U. and Widmalm, G. and Santer, M. and Barbirz, S.
Journal of the American Chemical Society 138 (29): 9109-9118. 27 July 2016

Sequence-specific DNA binding determined by contacts outside the helix-turn-helix motif of the ParB homolog KorB.
Khare, D. and Ziegelin, G. and Lanka, E. and Heinemann, U.
Nature Structural & Molecular Biology 11 (7): 656-663. 1 January 2004

Crystal structure of native and a mutant of Lampyris turkestanicus luciferase implicate in bioluminescence color shift.
Kheirabadi, M. and Sharafian, Z. and Naderi-Manesh, H. and Heinemann, U. and Gohlke, U. and Hosseinkhani, S.
Biochimica et Biophysica Acta - Proteins and Proteomics 1834 (12): 2729-2735. 6 October 2013

Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Kirchner, F. and Schuetz, A. and Boldt, L.H. and Martens, K. and Dittmar, G. and Haverkamp, W. and Thierfelder, L. and Heinemann, U. and Gerull, B.
Circulation Cardiovascular Genetics 5 (4): 400-411. 1 August 2012

Crystal structure of KorA bound to operator DNA: insight into repressor cooperation in RP4 gene regulation.
Koenig, B. and Mueller, J.J. and Lanka, E. and Heinemann, U.
Nucleic Acids Research 37 (6): 1915-1924. April 2009

Functional interaction of CCAAT/enhancer-binding-protein-α basic region mutants with E2F transcription factors and DNA.
Kowenz-Leutz, E. and Schuetz, A. and Liu, Q. and Knoblich, M. and Heinemann, U. and Leutz, A.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1859 (7): 841-847. July 2016

XDSAPP: a graphical user interface for the convenient processing of diffraction data using XDS.
Krug, M. and Weiss, M.S. and Heinemann, U. and Mueller, U.
Journal of Applied Crystallography 45 (3): 568-572. June 2012

Diversity in structure and function of tethering complexes: Evidence for different mechanisms in vesicular transport regulation.
Kuemmel, D. and Heinemann, U.
Current Protein & Peptide Science 9 (2): 197-209. April 2008

Unique self-palmitoylation activity of the transport protein particle component Bet3: A mechanism required for protein stability.
Kuemmel, D. and Heinemann, U. and Veit, M.
Proceedings of the National Academy of Sciences of the United States of America 103 (34): 12701-12706. 22 August 2006

Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2.
Kuemmel, D. and Mueller, J.J. and Roske, Y. and Henke, N. and Heinemann, U.
Journal of Molecular Biology 361 (1): 22-32. 4 August 2006

The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex.
Kuemmel, D. and Mueller, J.J. and Roske, Y. and Misselwitz, R. and Buessow, K. and Heinemann, U.
EMBO Reports 6 (8): 787-793. 6 August 2005

Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells.
Kuemmel, D. and Oeckinghaus, A. and Wang, C. and Krappmann, D. and Heinemann, U.
FEBS Letters 582 (27): 3729-3733. 12 November 2008

Structural studies of the human tethering complex TRAPP involved in vesicular transport.
Kuemmel, D. and Turnbull, A.P. and Mueller, J.J. and Roske, Y. and Heinemann, U.
2006

Characterization of the self-palmitoylation activity of the transport protein particle component Bet3.
Kuemmel, D. and Walter, J. and Heck, M. and Heinemann, U. and Veit, M.
Cellular and Molecular Life Sciences 67 (15): 2653-2664. August 2010

Purification and preliminary X-ray crystallographic studies of beta-microseminoprotein from human seminal plasma.
Kumar, V. and Roske, Y. and Singh, N. and Heinemann, U. and Singh, T.P. and Yadav, S.
Acta Crystallographica Section F 65 (5): 518-521. 1 May 2009

Solvent networks tune thermodynamics of oligosaccharide complex formation in an extended protein binding site.
Kunstmann, S. and Gohlke, U. and Broeker, N.K. and Roske, Y. and Heinemann, U. and Santer, M. and Barbirz, S.
Journal of the American Chemical Society 140 (33): 10447-10455. 22 August 2018

A MAS NMR study of the bacterial ABC transporter ArtMP.
Lange, V. and Becker-Baldus, J. and Kunert, B. and van Rossum, B.J. and Casagrande, F. and Engel, A. and Roske, Y. and Scheffel, F.M. and Schneider, E. and Oschkinat, H.
ChemBioChem 11 (4): 547-555. 1 March 2010

Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold.
Manjasetty, B.A. and Buessow, K. and Fieber-Erdmann, M. and Roske, Y. and Gobom, J. and Scheich, C. and Goetz, F. and Niesen, F.H. and Heinemann, U.
Protein Science 15 (4): 914-920. 1 April 2006

Crystal structure of Homo sapiens protein hp14.5.
Manjasetty, B.A. and Delbrueck, H. and Pham, D.T. and Mueller, U. and Fieber-Erdmann, M. and Scheich, C. and Sievert, V. and Buessow, K. and Niesen, F.H. and Weihofen, W. and Loll, B. and Saenger, W. and Heinemann, U.
Proteins: Structure, Function, and Bioinformatics 54 (3): 797-800. 1 March 2004

Structure of circularly permuted DsbAQ100T99: preserved global fold and local structural adjustments.
Manjasetty, B.A. and Hennecke, J. and Glockshuber, R. and Heinemann, U.
Acta Crystallographica Section D 60 (2): 304-309. 1 January 2004

Secure web book to store structural genomics research data.
Manjasetty, B.A. and Hoppner, K. and Mueller, U. and Heinemann, U.
Journal of Structural and Functional Genomics 4 (2-3): 121-127. 1 January 2003

X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880.
Manjasetty, B.A. and Niesen, F.H. and Delbrueck, H. and Goetz, F. and Sievert, V. and Buessow, K. and Behlke, J. and Heinemann, U.
Biological Chemistry 385 (10): 935-942. 1 January 2004

X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
Manjasetty, B.A. and Niesen, F.H. and Scheich, C. and Roske, Y. and Goetz, F. and Behlke, J. and Sievert, V. and Heinemann, U. and Buessow, K.
BMC Structural Biology 5 (14): 21. 14 December 2005

X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma.
Manjasetty, B.A. and Quedenau, C. and Sievert, V. and Buessow, K. and Niesen, F. and Delbrueck, H. and Heinemann, U.
Proteins: Structure, Function, and Bioinformatics 55 (1): 214-217. April 2004

Cellular pharmacology of the anti-hepatitis B virus agent beta-L-2',3'-didehydro-2',3'-dideoxy-N4-hydroxycytidine: relevance for activation in HepG2 cells.
Matthes, E. and Buenger, H.
Antimicrobial Agents and Chemotherapy 54 (1): 341-345. 16 January 2010

Optimized Variants of the Cold Shock Protein from in Vitro Selection: Structural Basis of Their High Thermostability.
Max, K.E. and Wunderlich, M. and Roske, Y. and Schmid, F.X. and Heinemann, U.
Journal of Molecular Biology 369 (4): 1087-1097. 15 June 2007

Common mode of DNA binding to cold shock domains: Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus.
Max, K.E. and Zeeb, M. and Bienert, R. and Balbach, J. and Heinemann, U.
FEBS Journal 274 (5): 1265-1279. March 2007

T-rich DNA single strands bind to a preformed site on the bacterial cold shock protein Bs-CspB.
Max, K.E.A. and Zeeb, M. and Bienert, R. and Balbach, J. and Heinemann, U.
Journal of Molecular Biology 360 (3): 702-714. 14 July 2006

Mechanisms of Lin28-mediated miRNA and mRNA regulation : a structural and functional perspective.
Mayr, F. and Heinemann, U.
International Journal of Molecular Sciences 14 (8): 16532-16553. 9 August 2013

The Lin28 cold-shock domain remodels pre-let-7 microRNA.
Mayr, F. and Schütz, A. and Dge, N. and Heinemann, U.
Nucleic Acids Research 40 (15): 7492-7506. 1 August 2012

Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Ming, Q. and Roske, Y. and Schuetz, A. and Walentin, K. and Ibraimi, I. and Schmidt-Ott, K.M. and Heinemann, U.
Nucleic Acids Research 46 (4): 2082-2095. 28 February 2018

Sequence specificity of single-stranded DNA-binding proteins: a novel DNA microarray approach.
Morgan, H.P. and Estibeiro, P. and Wear, M.A. and Max, K.E. and Heinemann, U. and Cubeddu, L. and Gallagher, M.P. and Sadler, P.J. and Walkinshaw, M.D.
Nucleic Acids Research 35 (10): e75. May 2007

New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108).
Mueller, A. and Mueller, J.J. and Muller, Y.A. and Uhlmann, H. and Bernhardt, R. and Heinemann, U.
Structure 6 (3): 269-280. 15 March 1998

An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri phage Sf6.
Mueller, J.J. and Barbirz, S. and Heinle, K. and Freiberg, A. and Seckler, R. and Heinemann, U.
Structure 16 (5): 766-775. 7 May 2008

Glass-capillary collimator for distance compensation and partial monochromatization at rotating-anode X-ray generators.
Mueller, J.J. and Gorny, H.E. and Schmalz, J. and Heinemann, U.
Journal of Applied Crystallography 28 (Pt 6): 853-855. 1 December 1995

Structural and thermodynamic characterization of the adrenodoxin-like domain of the electron-transfer protein Etp1 from Schizosaccharomyces pombe.
Mueller, J.J. and Hannemann, F. and Schiffler, B. and Ewen, K.M. and Kappl, R. and Heinemann, U. and Bernhardt, R.
Journal of Inorganic Biochemistry 105 (7): 957-965. July 2011

A study of high-resolution x-ray scattering data evaluation by the maximum-entropy method.
Mueller, J.J. and Hansen, S.
Journal of Applied Crystallography 27 (Pt 3): 257-270. 1 June 1994

Multimodal particle size distribution or fractal surface of acrylic acid copolymer nanoparticles: A small-angle X-ray scattering study using direct Fourier and indirect maximum entropy methods.
Mueller, J.J. and Hansen, S. and Lukowski, G. and Gast, K.
Journal of Applied Crystallography 28 (Pt 6): 774-781. 1 December 1995

The use of small-angle scattering and the maximum-entropy method for shape-model determination from distance-distribution functions.
Mueller, J.J. and Hansen, S. and Puerschel, H.V.
Journal of Applied Crystallography 29 (Pt 5): 547-554. 1 October 1996

MAD phasing.
Mueller, J.J. and Heinemann, U.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1002-1008. ISBN 3-540-44244-8 2006

Modeling of electrostatic recognition processes in the mammalian mitochondrial steroid hydroxylase system.
Mueller, J.J. and Lapko, A. and Ruckpaul, K. and Heinemann, U.
Biophysical Chemistry 100 (1-3): 281-292. December 2002

Low-resolution ab initio phasing of Sarcocystis muris lectin SML-2.
Mueller, J.J. and Lunina, N.L. and Urzhumtsev, A. and Weckert, E. and Heinemann, U. and Lunin, V.Y.
Acta Crystallographica Section D 62 (Pt 5): 533-540. May 2006

AKIMA interpolation: A tool used in direct slit-length desmearing procedures of non-frequency- limited X-ray scattering curves.
Mueller, J.J. and Mueller, E.C. and Gernat, C. and Kroeber, R.
Journal of Applied Crystallography 28 (Pt 1): 38-42. 1 February 1995

Crystal structure of barley 1,3-1,4-beta-glucanase at 2.0-A resolution and comparison with Bacillus 1,3-1,4-beta-glucanase.
Mueller, J.J. and Thomsen, K.K. and Heinemann, U.
Journal of Biological Chemistry 273 (6): 3438-3446. 6 February 1998

PAN-modular structure of microneme protein SML-2 from the parasite Sarcocystis muris at 1.95 Å resolution and its complex with 1-thio-β-D-galactose.
Mueller, J.J. and Weiss, M.S. and Heinemann, U.
Acta Crystallographica Section D 67 (Pt 11): 936-944. November 2011

The macromolecular crystallography beamlines at BESSY II of the Helmholtz-Zentrum Berlin: current status and perspectives.
Mueller, U. and Foerster, R. and Hellmig, M. and Huschmann, F.U. and Kastner, A. and Malecki, P. and Puehringer, S. and Roewer, M. and Sparta, K. and Steffien, M. and Uehlein, M. and Wilk, P. and Weiss, M.S.
European Physical Journal Plus 130 (7): 141. July 2015

Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags.
Mueller, U. and Buessow, K. and Diehl, A. and Bartl, F.J. and Niesen, F.H. and Nyarsik, L. and Heinemann, U.
Journal of Structural and Functional Genomics 4 (4): 217-225. December 2003

Molekuelmodelle und Modellmolekuele: Strukturanalyse grosser biologischer Molekuele fuer die Medizin.
Muller, Y.A. and Heinemann, U.
In: Grundlagen der Molekularen Medizin. Molekulare Medizin . Springer, Berlin [u.a.], 340-359. ISBN 3-540-43207-8 1 January 2003

Molekuelmodelle und Modellmolekuele: Strukturanalyse grosser biologischer Molekuele fuer die Medizin.
Muller, Y.A. and Heinemann, U.
In: Handbuch der molekularen Medizin, Band 1, Molekular- und zellbiologische Grundlagen. Springer, Berlin [u.a.], 340-359. ISBN 978-3-662-07589-0 2003

Mn2+-DNA interactions in aqueous systems: A Raman spectroscopic study.
Muntean, C.M. and Misselwitz, R. and Dostal, L. and Welfle, H.
Spectroscopy 20 (1): 29-35. January 2006

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.
Murakawa, Y. and Hinz, M. and Mothes, J. and Schuetz, A. and Uhl, M. and Wyler, E. and Yasuda, T. and Mastrobuoni, G. and Friedel, C.C. and Dölken, L. and Kempa, S. and Schmidt-Supprian, M. and Blüthgen, N. and Backofen, R. and Heinemann, U. and Wolf, J. and Scheidereit, C. and Landthaler, M.
Nature Communications 6 : 7367. 14 July 2015

An approach to quality management in structural biology: Biophysical selection of proteins for successful crystallization.
Niesen, F.H. and Koch, A. and Lenski, U. and Harttig, U. and Roske, Y. and Heinemann, U. and Hofmann, K.P.
Journal of Structural Biology 162 (3): 451-459. June 2008

A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Opitz, R. and Mueller, M. and Reuter, C. and Barone, M. and Soicke, A. and Roske, Y. and Piotukh, K. and Huy, P. and Beerbaum, M. and Wiesner, B. and Beyermann, M. and Schmieder, P. and Freund, C. and Volkmer, R. and Oschkinat, H. and Schmalz, H.G. and Kuehne, R.
Proceedings of the National Academy of Sciences of the United States of America 112 (16): 5011-5016. 21 April 2015

The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells.
Patzke, C. and Max, K.E. and Behlke, J. and Schreiber, J. and Schmidt, H. and Dorner, A.A. and Kroeger, S. and Henning, M. and Otto, A. and Heinemann, U. and Rathjen, F.G.
Journal of Neuroscience 30 (8): 2897-2910. 24 February 2010

Different inhibitory potencies of oseltamivir carboxylate, zanamivir, and several tannins on bacterial and viral neuraminidases as assessed in a cell-free fluorescence-based enzyme inhibition assay.
Quosdorf, S. and Schuetz, A. and Kolodziej, H.
Molecules 22 (11): 1989. 17 November 2017

Kristallstrukturanalyse des kohlenhydratbindenden Moduls 27-1 der Beta-Mannanase 26 aus Caldicellulosiruptor saccharolyticus im Komplex mit Mannohexaose und Kristallisation der ATPase HP0525 aus Helicobacter pylori.
Roske, Y.
UNSPECIFIED thesis, UNSPECIFIED. 28 July 2005

High-resolution crystal structures of Caldicellulosiruptor strain Rt8B.4 carbohydrate-binding module CBM27-1 and its complex with mannohexaose.
Roske, Y. and Sunna, A. and Pfeil, W. and Heinemann, U.
Journal of Molecular Biology 340 (3): 543-554. 9 July 2004

RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.
Sachs, R. and Max, K.E. and Heinemann, U. and Balbach, J.
RNA 18 (1): 65-76. January 2012

Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain.
Saupe, J. and Roske, Y. and Schillinger, C. and Kamdem, N. and Radetzki, S. and Diehl, A. and Oschkinat, H. and Krause, G. and Heinemann, U. and Rademann, J.
ChemMedChem 6 (8): 1411-1422. 1 August 2011

Vectors for co-expression of an unrestricted number of proteins.
Scheich, C. and Kuemmel, D. and Soumailakakis, D. and Heinemann, U. and Buessow, K.
Nucleic Acids Research 35 (6): e43. March 2007

Peptide linkage to the α-subunit of MHCII creates a stably inverted antigen presentation complex.
Schlundt, A. and Guenther, S. and Sticht, J. and Wieczorek, M. and Roske, Y. and Heinemann, U. and Freund, C.
Journal of Molecular Biology 423 (3): 294-302. 26 October 2012

Roquin binding to target mRNAs involves a winged helix-turn-helix motif.
Schuetz, A. and Murakawa, Y. and Rosenbaum, E. and Landthaler, M. and Heinemann, U.
Nature Communications 5 : 5701. 11 December 2014

The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation.
Schuetz, A. and Nana, D. and Rose, C. and Zocher, G. and Milanovic, M. and Koenigsmann, J. and Blasig, R. and Heinemann, U. and Carstanjen, D.
Cellular and Molecular Life Sciences 68 (18): 3121-3131. September 2011

Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Schuetz, A. and Radusheva, V. and Krug, S.M. and Heinemann, U.
Annals of the New York Academy of Sciences 1405 (1): 147-159. October 2017

Structural and functional characterization of human Iba proteins.
Schulze, J.O. and Quedenau, C. and Roske, Y. and Adam, T. and Schueler, H. and Behlke, J. and Turnbull, A.P. and Sievert, V. and Scheich, C. and Mueller, U. and Heinemann, U. and Buessow, K.
FEBS Journal 275 (18): 4627-4640. September 2008

Bacteriophage P22 tailspike: structure of the complete protein and function of the interdomain linker.
Seul, A. and Müller, J.J. and Andres, D. and Stettner, E. and Heinemann, U. and Seckler, R.
Acta Crystallographica Section D 70 (Pt 5): 1336-1345. May 2014

XDSAPP2.0.