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Jump to: ?? phd ?? | Abdelilah-Seyfried, Salim | Akalin, Altuna (BIMSB) | Alexander, Christiane | Andrade Navarro, Miguel | Bader, Michael | Bargou, Ralf C. | Behlke, Joachim | Bergmann, Martin W. | Besser, Daniel | Beule, Dieter (MDC/BIH) | Bielka, Heinz | Bimmler, Marion | Birchmeier, Walter | Birchmeier-Kohler, Carmen | Blankenstein, Thomas | Calkhoven, Cornelis F. | Cardoso, Cristina | Chekulaeva, Marina (BIMSB) | Chen, Wei (BIMSB/BIH) | Damaschun, Gregor | Daniel, Peter | Daumke, Oliver | De la Rosa, Kathrin | Deubzer, Hedwig (ECRC) | Di Virgilio, Michela | Diecke, Sebastian (MDC/BIH) | Dietz, Rainer | Dittmar, Gunnar | Doerken, Bernd (MDC/ECRC) | Falcke, Martin | Falk, Kirsten | Fichtner, Iduna | Fielitz, Jens (ECRC) | Fischer, Christian (ECRC) | Forslund, Sofia (MDC/ECRC) | Ganten, Detlev | Gargiulo, Gaetano | Garratt, Alistair N. | Geier, Christian (ECRC) | Gerhardt, Holger | Gerull, Brenda | Gollasch, Maik (ECRC) | Gossen, Manfred | Gotthardt, Michael | Hammes-Lewin, Annette | Heinemann, Udo | Henssen, Anton (MDC/ECRC) | Heuser, Arnd | Hirsch, Christian | Hoepken, Uta | Huebner, Norbert | Ivics, Zoltan | Izsvak, Zsuzsanna | Janz, Martin / Mathas, Stephan (MDC/ECRC) | Jentsch, Thomas | Jung, Christiane | Junker, Jan Philipp (BIMSB) | Karsten, Uwe | Kemmner, Wolfgang | Kempa, Stefan (BIMSB) | Kempermann, Gerd | Kettenmann, Helmut | Kettritz, Ralph (ECRC) | Kirwan, Jennifer (MDC/BIH) | Klaassen, Sabine (ECRC) | Klussmann, Enno | Koehler, Matthias | Krappmann, Daniel | Kuehn, Ralf (MDC/BIH) | Lacadie, Scott | Landthaler, Markus (BIMSB) | Leutz, Achim | Lewin, Gary | Lipp, Martin | Loewer, Alexander (BIMSB) | Luft, Friedrich C. (MDC/ECRC) | Lupianez, Dario (BIMSB) | Matthes, Eckart | Mertins, Philipp (MDC/BIH) | Meyer, Irmtraud (BIMSB) | Morano, Ingo | Mueller, Dominik N. (MDC/ECRC) | Mueller, Dominik N. / Dechend, Ralph (ECRC) | Na, Il-Kang (ECRC) | Niendorf, Thoralf | Obermayer, Benedikt | Ohler, Uwe (BIMSB) | Panakova, Daniela | Paul, Friedemann (ECRC) | Peters, Oliver (ECRC) | Pezzutto, Antonio | Pombo, Ana (BIMSB) | Poole, Kathryn | Poulet, James | Poy, Matthew | Preibisch, Stephan (BIMSB) | Preissner, Robert | Prigione, Alessandro | Purfuerst, Bettina | Raile, Klemens (ECRC) | Rajewsky, Klaus | Rajewsky, Nikolaus (BIMSB) | Rathjen, Fritz G. | Rehm, Armin | Reich, Jens | Reszka, Regina | Rocks, Oliver | Roepke, Torsten Kai (ECRC) | Roetzschke, Olaf | Rosenbauer, Frank | Ruckpaul, Klaus | Sauer, Sascha (BIMSB/BIH) | Saumweber, Harald | Scheidereit, Claus | Scherneck, Siegfried | Schmidt-Ott, Kai | Schmitt, Clemens | Schreiber, Adrian (ECRC) | Schuetz, Anja | Schulz-Menger, Jeanette (ECRC) | Schunck, Wolf-Hagen | Schwarz, Roland (BIMSB) | Selbach, Matthias | Sieweke, Michael | Siffrin, Volker (ECRC) | Sklenar, Heinz | Sommer, Thomas | Spagnoli, Francesca | Sperling, Silke (ECRC) | Sporbert, Anje | Spuler, Simone (ECRC) | Stade, Katrin | Stein, Ulrike (MDC/ECRC) | Tannert, Christof | Thierfelder, Ludwig | Tursun, Baris (BIMSB) | Uckert, Wolfgang | Von Kries, Jens Peter / Nazaré, Marc | Waiczies, Sonia (ECRC) | Walther, Wolfgang | Wang, Jichang | Wanker, Erich | Welfle, Heinz | Willnow, Thomas E. | Wittmann-Liebold, Brigitte | Woehler, Andrew (BIMSB) | Wolf, Jana | Wunderlich, Volker | Zenke, Martin | Ziebold, Ulrike | Zinzen, Robert (BIMSB)

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Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A. and Xavier, A. and Abu Lubad, M. and Sigulla, J. and Kessler, M. and Hurwitz, R. and Meyer, T.F.
EBioMedicine 23 : 100-110. September 2017

Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L. and Peeva, P. and Ramos-Prats, A. and Alenina, N. and Winter, Y. and Rivalan, M.
Behavioural Brain Research 29 August 2019 (In Press)

Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.
Anders, K. and Buschow, C. and Charo, J. and Blankenstein, T.
Transgenic Research 21 (5): 1099-1107. October 2012

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K. and Buschow, C. and Herrmann, A. and Milojkovic, A. and Loddenkemper, C. and Kammertoens, T. and Daniel, P. and Yu, H. and Charo, J. and Blankenstein, T.
Cancer Cell 20 (6): 755-767. 13 December 2011

Colon cancer metastasis: MACC1 and Met as metastatic pacemakers.
Arlt, F. and Stein, U.
International Journal of Biochemistry and Cell Biology 41 (12): 2356-2359. December 2009

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A. and Roske, Y. and Barth, C. and Lleras Forero, L. and Bravo-Rodriguez, K. and Redel, Al. and Kostova, S. and McShane, E. and Opitz, R. and Faelber, K. and Rau, K. and Mielke, T. and Daumke, O. and Selbach, M. and Sanchez-Garcia, E. and Rocks, O. and Panáková, D. and Heinemann, U. and Wanker, E.E.
Nature Communications 7 : 13047. 20 October 2016

A chronic model of arthritis supported by a strain-specific periarticular lymph node in BALB/c mice.
Baddack, U. and Hartmann, S. and Bang, H. and Grobe, J. and Loddenkemper, C. and Lipp, M. and Mueller, G.
Nature Communications 4 : 1644. 2013

Protein dislocation from the ER.
Bagola, K. and Mehnert, M. and Jarosch, E. and Sommer, T.
Biochimica et Biophysica Acta - Biomembranes 1808 (3): 925-936. March 2011

Protein quality control: On IPODs and other JUNQ.
Bagola, K. and Sommer, T.
Current Biology 18 (21): R1019-R1021. 11 November 2008

Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K. and von Delbrück, M. and Dittmar, G. and Scheffner, M. and Ziv, I. and Glickman, M.H. and Ciechanover, A. and Sommer, T.
Molecular Cell 50 (4): 528-539. 23 May 2013

Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases.
Bandapalli, O.R. and Geheeb, M. and Kobelt, D. and Kuehnle, K. and Elezkurtaj, S. and Herrmann, J. and Gressner, A.M. and Weiskirchen, R. and Beule, D. and Bluethgen, N. and Herzel, H. and Franke, C. and Brand, K.
International Journal of Cancer 118 : 74-89. 1 January 2006

Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A. and Zelarayan, L. and Betney, R. and Gehrke, C. and Dunger, S. and Noack, C. and Busjahn, A. and Huelsken, J. and Taketo, M.M. and Birchmeier, W. and Dietz, R. and Bergmann, M.W.
Circulation Research 100 (9): 1353-1362. 11 May 2007

PRC1-mediated gene silencing in pluripotent ES cells: function and evolution.
Becker, M. and Mah, N. and Zdzieblo, D. and Li, X. and Mer, A.S. and Andrade-Navarro, M.A. and Mueller, A.M.
Epigenetics and Human Health 2015 : 141-166. 18 November 2014

The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration.
Becker, M.S. and Müller, P.M. and Bajorat, J. and Schroeder, A. and Giaisi, M. and Amin, E. and Ahmadian, M.R. and Rocks, O. and Köhler, R. and Krammer, P.H. and Li-Weber, M.
Oncotarget 7 (32): 51908-51921. 9 August 2016

Structural identification of the VPS18 β-propeller reveals a critical role in the HOPS complex stability and function.
Behrmann, H. and Lürick, A. and Kuhlee, A. and Kleine Balderhaar, H. and Bröcker, C. and Kümmel, D. and Engelbrecht-Vandré, S. and Gohlke, U. and Raunser, S. and Heinemann, U. and Ungermann, C.
Journal of Biological Chemistry 289 (48): 33503-33512. 28 November 2014

Modeling Wnt/β-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions.
Benary, U. and Kofahl, B. and Hecht, A. and Wolf, J.
Frontiers in Physiology 4 : 21. 25 February 2013

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.
Bendle, G.M. and Linnemann, C. and Hooijkaas, A.I. and Bies, L. and de Witte, M.A. and Jorritsma, A. and Kaiser, A.D.M. and Pouw, N. and Debets, R. and Kieback, E. and Uckert, W. and Song, J.Y. and Haanen, J.B.A.G. and Schumacher, T.N.M.
Nature Medicine 16 (5): 565-570, 1p following 570. May 2010

Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues.
Benndorf, R. and Gilmont, R.R. and Hirano, S. and Ransom, R.F. and Jungblut, P.R. and Bommer, M. and Goldman, J.E. and Welsh, M.J.
Cell Stress & Chaperones 23 (5): 813-826. September 2018

Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune, M.T. and Gee, M.H. and Bunse, M. and Lee, M.S. and Gschweng, E.H. and Pagadala, M.S. and Zhou, J. and Cheng, D. and Heath, J.R. and Kohn, D.B. and Kuhns, M.S. and Uckert, W. and Baltimore, D.
eLife 5 : e19095. 8 November 2016

Replicative aging and differentiation potential of human adipose tissue-derived mesenchymal stromal cells expanded in pooled human or fetal bovine serum.
Bieback, K. and Hecker, A. and Schlechter, T. and Hofmann, I. and Brousos, N. and Redmer, T. and Besser, D. and Klueter, H. and Mueller, A.M. and Becker, M.
Cytotherapy 14 (5): 570-583. May 2012

Single-stranded DNA bound to bacterial cold-shock proteins: preliminary crystallographic and Raman analysis.
Bienert, R. and Zeeb, M. and Dostal, L. and Feske, A. and Magg, C. and Max, K. and Welfle, H. and Balbach, J. and Heinemann, U.
Acta Crystallographica Section D 60 (4): 755-757. 1 January 2004

High-throughput omics technologies: Potential tools for the investigation of influences of EMF on biological systems.
Blankenburg, M. and Haberland, L. and Elvers, H.D. and Tannert, C. and Jandrig, B.
Current Genomics 10 (2): 86-92. April 2009

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J. and Kieback, E. and Marino, S.F. and Oden, F. and Westermann, J. and Chmielewski, M. and Abken, H. and Uckert, W. and Höpken, U.E. and Rehm, A.
Molecular Therapy 26 (8): 1906-1920. 1 August 2018

The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A. and Babila, J.T. and Wiglenda, T. and Diez, L. and Jacob, M. and Nietfeld, W. and Huska, M.R. and Haenig, C. and Groenke, N. and Buntru, A. and Blanc, E. and Meier, J.C. and Vannoni, E. and Erck, C. and Friedrich, B. and Martens, H. and Neuendorf, N. and Schnoegl, S. and Wolfer, D.P. and Loos, M. and Beule, D. and Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26 (1): 109-120. 17 January 2019

Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme.
Boehm, K. and Herter, T. and Mueller, J.J. and Borriss, R. and Heinemann, U.
FEBS Journal 277 (5): 1284-1296. March 2010

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B. and Eichelbaum, K. and Sadewasser, A. and Wang, X. and Husic, I. and Paki, K. and Hergeselle, M. and Vetter, B. and Hou, J. and Chen, W. and Wiebusch, L. and Meyer, I.M. and Wolff, T. and Selbach, M.
bioRxiv : 438176. 8 October 2018

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G. and Kleinewietfeld, M. and Di Mitri, D. and Sternjak, A. and Diamantini, A. and Giometto, R. and Hoepner, S. and Centonze, D. and Bernardi, G. and Dell'Acqua, M.L. and Rossini, P.M. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 110 (4): 1225-1232. 15 August 2007

A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand, J. and Smith, E.S.J. and Schwefel, D. and Lapatsina, L. and Poole, K. and Omerbasic, D. and Kozlenkov, A. and Behlke, J. and Lewin, G.R. and Daumke, O.
EMBO Journal 31 (17): 3635-3646. 29 August 2012

BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H. and Wiese, M. and Zatula, N. and Grigoryan, T. and Dai, Y. and Fritzmann, J. and Birchmeier, W.
Gastroenterology 141 (4): 1359-1370. October 2011

Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates.
Briesemeister, D. and Friese, C. and Isern, C.C. and Dietz, E. and Blankenstein, T. and Thoene-Reineke, C. and Kammertoens, T.
Cytokine 60 (3): 626-633. December 2012

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis.
Briesemeister, D. and Sommermeyer, D. and Loddenkemper, C. and Loew, R. and Uckert, W. and Blankenstein, T. and Kammertoens, T.
International Journal of Cancer 128 (2): 371-378. 15 January 2011

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, A.M. and Vockentanz, L. and Kharazi, S. and Huska, M.R. and Mancini, E. and Scheller, M. and Kuhl, C. and Enns, A. and Prinz, M. and Jaenisch, R. and Nerlov, C. and Leutz, A. and Andrade-Navarro, M.A. and Jacobsen, S.E. and Rosenbauer, F.
Nature Genetics 41 (11): 1207-1215. November 2009

Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy.
Brueckner, B. and Rius, M. and Rivera Markelova, M. and Fichtner, I. and Hals, P.A. and Sandvold, M.L. and Lyko, F.
Molecular Cancer Therapeutics 9 (5): 1256-1264. May 2010

RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer.
Bunse, M. and Bendle, G.M. and Linnemann, C. and Bies, L. and Schulz, S. and Schumacher, T.N. and Uckert, W.
Molecular Therapy 22 (11): 1983-1991. November 2014

In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance.
Buschow, C. and Charo, J. and Anders, K. and Loddenkemper, C. and Jukica, A. and Alsamah, W. and Perez, C. and Willimsky, G. and Blankenstein, T.
Journal of Immunology 184 (6): 2930-2938. 15 March 2010

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types.
Calabrese, C. and Davidson, N.R. and Fonseca, N.A. and He, Y. and Kahles, A. and Lehmann, K.V. and Liu, F. and Shiraishi, Y. and Soulette, C.M. and Urban, L. and Demircioğlu, D. and Greger, L. and Li, S. and Liu, D. and Perry, M.D. and Xiang, L. and Zhang, F. and Zhang, J. and Bailey, P. and Erkek, S. and Hoadley, K.A. and Hou, Y. and Kilpinen, H. and Korbel, J.O. and Marin, M.G. and Markowski, J. and Nandi, T. and Pan-Hammarström, Q. and Pedamallu, C.S. and Siebert, R. and Stark, S.G. and Su, H. and Tan, P. and Waszak, S.M. and Yung, C. and Zhu, S. and Awadalla, P. and Creighton, C.J. and Meyerson, M. and Ouellette, B.F.F. and Wu, K. and Yang, H. and Brazma, A. and Brooks, A.N. and Göke, J. and Rätsch, G. and Schwarz, R.F. and Stegle, O. and Zhang, Z.
bioRxiv : 183889. 12 March 2018

Assessing the gene regulatory landscape in 1,188 human tumors.
Calabrese, C. and Lehmann, K.V. and Urban, L. and Liu, F. and Erkek, S. and Fonseca, N. and Kahles, A. and Kilpinen-Barrett, L.H. and Markowski, J. and Waszak, S. and Korbel, J. and Zhang, Z. and Brazma, A. and Raetsch, G. and Schwarz, R. and Stegle, O.
bioRxiv : 225441. 29 November 2017

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P. and Sasaki, Y. and Godinho, S.A. and Pellerin, A. and Köchert, K. and Sleckman, B.P. and de Alboran, I.M. and Janz, M. and Rodig, S. and Rajewsky, K.
Nature Immunology 13 (11): 1092-1100. November 2012

Detecting actively translated open reading frames in ribosome profiling data.
Calviello, L. and Mukherjee, N. and Wyler, E. and Zauber, H. and Hirsekorn, A. and Selbach, M. and Landthaler, M. and Obermayer, B. and Ohler, U.
Nature Methods 13 (2): 165-170. February 2016

Beyond read-counts: Ribo-seq data analysis to understand the functions of the transcriptome.
Calviello, L. and Ohler, U.
Trends in Genetics 33 (10): 728-744. October 2017

Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data.
Calviello, L. and Sydow, D. and Harnett, D. and Ohler, U.
bioRxiv : 601468. 8 April 2019

DDX3 depletion selectively represses translation of structured mRNAs.
Calviello, L. and Venkataramanan, S. and Rogowski, K.J. and Wyler, E. and Tejura, M. and Thai, B. and Krol, J. and Filipowicz, W. and Landthaler, M. and Floor, S.N.
bioRxiv : 589218. 26 March 2019

In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine.
Cayeux, S. and Bukarica, B. and Buschow, C. and Charo, J. and Bunse, M. and Doerken, B. and Blankenstein, T.
Gene Therapy 14 (20): 1481-1491. October 2007

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N. and Naumann, H. and Ruzittu, S. and Mah, N. and Pongrac, I.M. and Cozzitorto, C. and Hommel, A. and Andrade-Navarro, M.A. and Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8 : 14127. 13 February 2017

Comparing agent‐based delivery of DNA and PNA forced intercalation (FIT) probes for multicolor mRNA imaging.
Chamiolo, J. and Fang, G.M. and Hövelmann, F. and Friedrich, D. and Knoll, A. and Loewer, A. and Seitz, O.
ChemBioChem 20 (4): 595-604. 15 February 2019

Visualizing the dynamic of adoptively transferred T cells during the rejection of large established tumors.
Charo, J. and Perez, C. and Buschow, C. and Jukica, A. and Czeh, M. and Blankenstein, T.
European Journal of Immunology 41 (11): 3187-3197. November 2011

STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
Chatterjee, M. and Jain, S. and Stuehmer, T. and Andrulis, M. and Ungethuem, U. and Kuban, R.J. and Lorentz, H. and Bommert, K. and Topp, M. and Kramer, D. and Mueller-Hermelink, H. K. and Einsele, H. and Greiner, A. and Bargou, R.C.
Blood 109 (2): 720-728. 15 January 2007

Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X. and Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214 (11): 3417-3433. 6 November 2017

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R. and Sternjak, A. and Wend, P. and Momma, S. and Campos, B. and Herrmann, I.M. and Graf, D. and Mitsiadis, T. and Herold-Mende, C. and Besser, D. and Synowitz, M. and Kettenmann, H. and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

c-Met is essential for wound healing in the skin.
Chmielowiec, J. and Borowiak, M. and Morkel, M. and Stradal, T. and Munz, B. and Werner, S. and Wehland, J. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

CRISPR/Cas9-mediated in vitro mutagenesis in GC-like B cells.
Chu, V.T. and Graf, R. and Rajewsky, K.
Methods in Molecular Biology 1623 : 135-145. 2017

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T. and Graf, R. and Wirtz, T. and Weber, T. and Favret, J. and Li, X. and Petsch, K. and Tran, N.T. and Sieweke, M.H. and Berek, C. and Kühn, R. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (44): 12514-12519. 1 November 2016

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.
Chu, V.T. and Weber, T. and Graf, R. and Sommermann, T. and Petsch, K. and Sack, U. and Volchkov, P. and Rajewsky, K. and Kühn, R.
BMC Biotechnology 16 (1): 4. 16 January 2016

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu, V.T. and Weber, T. and Wefers, B. and Wurst, W. and Sander, S. and Rajewsky, K. and Kühn, R.
Nature Biotechnology 33 (5): 543-548. May 2015

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. and Rom, A. and Franke, V. and Imami, K. and Arrey, G. and Terne, M. and Woehler, A. and Akalin, A. and Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR.
Clauss, J. and Obenaus, M. and Miskey, C. and Ivics, Z. and Izsvák, Z. and Uckert, W. and Bunse, M.
Human Gene Therapy 29 (5): 569-584. May 2018

The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.
Coel Arslan, S. and Scheidereit, C.
PLoS ONE 6 (10): e26069. 10 October 2011

Wnt11/Fzd7 signaling compartmentalizes AKAP2/PKA to regulate L-type Ca2+ channel.
Csalyi, K.D. and Rharass, T. and Schulz, M. and Phan, M.H.Q. and Wakula, P. and Mhatre, K.N. and Plotnick, D. and Werdich, A.A. and Zauber, H. and Sury, M.D. and Selbach, M. and Heinzel, F.R. and Klussmann, E. and Panakova, D.
bioRxiv : 741637. 20 August 2019

Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.
Dahlmann, M. and Sack, U. and Herrmann, P. and Lemm, M. and Fichtner, I. and Schlag, P.M. and Stein, U.
Oncotarget 3 (8): 783-797. 7 August 2012

Control of gene editing by manipulation of DNA repair mechanisms.
Danner, E. and Bashir, S. and Yumlu, S. and Wurst, W. and Wefers, B. and Kühn, R.
Mammalian Genome 28 (7-8): 262-274. August 2017

Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module.
Daumke, O. and Gao, S. and von der Malsburg, A. and Haller, O. and Kochs, G.
Small GTPases 1 (1): 62-64. July 2010

The MYCmRNA3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.
Dejure, F.R. and Royla, N. and Herold, S. and Kalb, J. and Walz, S. and Ade, C.P. and Mastrobuoni, G. and Vanselow, J.T. and Schlosser, A. and Wolf, E. and Kempa, S. and Eilers, M.
EMBO Journal 36 (13): 1854-1868. 3 July 2017

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V. and Rosen, D.B. and Wang, Q. and Gazumyan, A. and Pai, J.A. and Oliveira, T.Y. and Sundaravinayagam, D. and Zhang, W. and Andreani, M. and Keller, L. and Kieffer-Kwon, K.R. and Pękowska, A. and Jung, S. and Driesner, M. and Subbotin, R.I. and Casellas, R. and Chait, B.T. and Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72 (4): 636-649. 15 November 2018

Stage-specific metabolic features of differentiating neurons: implications for toxicant sensitivity.
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PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
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A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
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Proteasomal degradation of misfolded proteins.
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The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment.
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New modules for the repeated internal and N-terminal epitope tagging of genes in Saccharomyces cerevisiae.
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Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.
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Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
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The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
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Emotional voice processing: investigating the role of genetic variation in the serotonin transporter across development.
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Bio++: efficient extensible libraries and tools for computational molecular evolution.
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AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
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McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.
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Dynamin-like MxA GTPase: Structural insights into oligomerization and implications for antiviral activity.
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Comparative profiling of the novel epothilone, sagopilone, in xenografts derived from primary non-small cell lung cancer.
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Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
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Paracrine and autocrine regulation of gene expression by Wnt-inhibitor Dickkopf in wild-type and mutant hepatocytes.
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Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
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A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis.
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A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
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The ubiquitylation machinery of the endoplasmic reticulum.
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Coping with stress: cellular relaxation techniques.
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Trends in Cell Biology 16 (12): 657-663. December 2006

The chemokine receptor CCR7 controls lymph node-dependent cytotoxic T cell priming in alloimmune responses.
Hoepken, U.E. and Droese, J. and Li, J.P. and Joergensen, J. and Breitfeld, D. and Zerwes, H.G. and Lipp, M.
European Journal of Immunology 34 (2): 461-470. 1 January 2004

The ratio between dendritic cells and T cells determines the outcome of their encounter: Proliferation versus deletion.
Hoepken, U.E. and Lehmann, I. and Droese, J. and Lipp, M. and Schueler, T. and Rehm, A.
European Journal of Immunology 35 (10): 2851-2863. 23 September 2005

CCR7 regulates lymphocyte egress and recirculation through body cavities.
Hoepken, U.E. and Winter, S. and Achtman, A.H. and Krueger, K. and Lipp, M.
Journal of Leukocyte Biology 87 (4): 671-682. April 2010

Small organic compounds enhance antigen-loading of class II MHC proteins by targeting the polymorphic P1 pocket.
Hoepner, S. and Dickhaut, K. and Hofstaetter, M. and Kraemer, H. and Rueckerl, D. and Soederhaell, J.A. and Gupta, S. and Marin-Esteban, V. and Kuehne, R. and Freund, C. and Jung, G. and Falk, K. and Roetzschke, O.
Journal of Biological Chemistry 281 (50): 38535-38542. 15 December 2006

A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.
Hofgaard, P.O. and Jodal, H.C. and Bommert, K. and Huard, B. and Caers, J. and Carlsen, H. and Schwarzer, R. and Schuenemann, N. and Jundt, F. and Lindeberg, M.M. and Bogen, B.
PLoS ONE 7 (12): e51892. 20 December 2012

Screening for large rearrangements of the BRCA1 gene in German breast or ovarian cancer families using semi-quantitative multiplex PCR method.
Hofmann, W. and Goergens, H. and John, A. and Horn, D. and Huettner, C. and Arnold, N. and Scherneck, S. and Schackert, H.K.
Human Mutation 22 (1): 103-104. 1 July 2003

The BRCA2 variant 8204G>A is a splicing mutation and results in an in frame deletion of the gene.
Hofmann, W. and Horn, D. and Huettner, C. and Classen, E. and Scherneck, S.
Journal of Medical Genetics 40 : e23. 1 March 2003

Identification of a recurrent BRCA1 mutation in German breast-cancer and/or ovarian-cancer families.
Hofmann, W. and Jandrig, B. and Classen, E. and Nestle-Kraemling, C. and Chang-Claude, J. and Scherneck, S.
Journal of Cancer Research and Clinical Oncology 127 (3): 200-202. 1 January 2001

Combined Wnt/β-catenin, met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome.
Holland, J.D. and Györffy, B. and Vogel, R. and Eckert, K. and Valenti, G. and Fang, L. and Lohneis, P. and Elezkurtaj, S. and Ziebold, U. and Birchmeier, W.
Cell Reports 5 (5): 1214-1227. 12 December 2013

RNA tomography for spatially resolved transcriptomics (Tomo-seq).
Holler, K. and Junker, J.P.
Methods in Molecular Biology 1920 : 129-141. 2019

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C. and Hanna, J. and Hirsch, C. and Volkwein, C. and Schütz, A. and Heinemann, U. and Sommer, T. and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D. and Schön, C. and Loddenkemper, C. and Lohneis, P. and Kühl, A.A. and Sommermann, T. and Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis.
Hsu, P.Y. and Calviello, L. and Wu, H.Y.L. and Li, F.W. and Rothfels, C.J. and Ohler, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 113 (45): E7126-E7135. 8 November 2016

Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F. and a Dzaye, O.D. and Hahn, A. and Yu, Y. and Scavetta, R.J. and Dittmar, G. and Kaczmarek, A.K. and Dunning, K.R. and Ricciardelli, C. and Rinnenthal, J.L. and Heppner, F.L. and Lehnardt, S. and Synowitz, M. and Wolf, S.A. and Kettenmann, H.
Neuro-Oncology 17 (2): 200-210. February 2015

JAMM: a peak finder for joint analysis of NGS replicates.
Ibrahim, M.M. and Lacadie, S.A. and Ohler, U.
Bioinformatics 31 (1): 48-55. 1 January 2015

Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
Nature Communications 9 (1): 4472. 26 October 2018

Determinants of transcription initiation directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
bioRxiv : 224642. 24 November 2017

High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.
Ilm, K. and Kemmner, W. and Osterland, M. and Burock, S. and Koch, G. and Herrmann, P. and Schlag, P.M. and Stein, U.
Molecular Cancer 14 (1): 38. 14 February 2015

Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during mitosis.
Imami, K. and Milek, M. and Bogdanow, B. and Yasuda, T. and Kastelic, N. and Zauber, H. and Ishihama, Y. and Landthaler, M. and Selbach, M.
Molecular Cell 72 (1): 84-98. 4 October 2018

SURF1 mutations causative of Leigh syndrome impair human neurogenesis.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Juettner, R. and Zink, A. and Mlody, B. and Glazar, P. and Secker, C. and Ciptasari, U.H. and Stenzel, W. and Hahn, T. and Diecke, S. and Priller, J. and Gotthardt, M. and Kuehn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
bioRxiv : 551390. 20 February 2019

Yos9p assists in the degradation of certain non-glycosylated proteins from the endoplasmic reticulum.
Jaenicke, L.A. and Brendebach, H. and Selbach, M. and Hirsch, C.
Molecular Biology of the Cell 22 (16): 2937-2945. August 2011

Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H. and Kase, J. and Doerr, J.R. and Milanovic, M. and Lenze, D. and Grau, M. and Beuster, G. and Ji, S. and Reimann, M. and Lenz, P. and Hummel, M. and Doerken, B. and Lenz, G. and Scheidereit, C. and Schmitt, C.A. and Lee, S.
Genes & Development 25 (20): 2137-2146. 15 October 2011

NF-κB in cellular senescence and cancer treatment.
Jing, H. and Lee, S.
Molecules and Cells 37 (3): 189-195. 31 March 2014

Promoter identification and transcriptional regulation of the metastasis gene MACC1 in colorectal cancer.
Juneja, M. and Ilm, K. and Schlag, P.M. and Stein, U.
Molecular Oncology 7 (5): 929-943. October 2013

Massively parallel clonal analysis using CRISPR/Cas9 induced genetic scars.
Junker, J.P. and Spanjaard, B. and Peterson-Maduro, J. and Alemany, A. and Hu, B. and Florescu, M. and van Oudenaarden, A.
bioRxiv : 056499. 4 January 2017

Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.
Kabrani, E. and Chu, V.T. and Tasouri, E. and Sommermann, T. and Baßler, K. and Ulas, T. and Zenz, T. and Bullinger, L. and Schultze, J.L. and Rajewsky, K. and Sander, S.
Blood 132 (25): 2670-2683. 20 December 2018

Development of mouse model systems of germinal center lymphomas.
Kabrani, E. and Sander, S.
Methods in Molecular Biology 1623 : 233-242. 2017

B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin).
Kammertoens, T. and Qin, Z. and Briesemeister, D. and Bendelac, A. and Blankenstein, T.
International Journal of Cancer 131 (7): 1499-1508. 1 October 2012

Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling.
Karabacak Calviello, A. and Hirsekorn, A. and Wurmus, R. and Yusuf, D. and Ohler, U.
Genome Biology 20 (1): 42. 21 February 2019

Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets via protocol-specific bias modeling.
Karabacak Calviello, A. and Hirsekorn, A. and Wurmus, R. and Yusuf, D. and Ohler, U.
bioRxiv : 284364. 19 March 2018

mRNA interactome capture in mammalian cells.
Kastelic, N. and Landthaler, M.
Methods 126 : 38-43. 15 August 2017

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.
Kaufman, W.L. and Kocman, I. and Agrawal, V. and Rahn, H.P. and Besser, D. and Gossen, M.
Nucleic Acids Research 36 (17): e111. October 2008

Transcriptional expression profile of cultured human embryonic stem cells in vitro and in vivo.
Keil, M. and Siegert, A. and Eckert, K. and Gerlach, J. and Haider, W. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 48 (3): 165-174. March 2012

Loss of UDP-N-acetylglucosamine 2-epimerase/ N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells.
Kemmner, W. and Kessel, P. and Sanchez-Ruderisch, H. and Moeller, H. and Hinderlich, S. and Schlag, P.M. and Detjen, K.
FASEB Journal 26 (2): 938-946. February 2012

Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer.
Kemmner, W. and Wan, K. and Ruttinger, S. and Ebert, B. and Macdonald, R. and Klamm, U. and Moesta, K.T.
FASEB Journal 22 (2): 500-509. February 2008

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer.
Kieback, E. and Charo, J. and Sommermeyer, D. and Blankenstein, T. and Uckert, W.
Proceedings of the National Academy of Sciences of the United States of America 105 (2): 623-628. 15 January 2008

Factors influencing subcellular localization of the human papillomavirus L2 minor structural protein.
Kieback, E. and Mueller, M.
Virology 345 (1): 199-208. 5 February 2006

Enhanced T cell receptor gene therapy for cancer.
Kieback, E. and Uckert, W.
Expert Opinion on Biological Therapy 10 (5): 749-762. May 2010

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity.
Kieback, E. and Hilgenberg, E. and Stervbo, U. and Lampropoulou, V. and Shen, P. and Bunse, M. and Jaimes, Y. and Boudinot, P. and Radbruch, A. and Klemm, U. and Kühl, A.A. and Liblau, R. and Hoevelmeyer, N. and Anderton, S.M. and Uckert, W. and Fillatreau, S.
Immunity 44 (5): 1114-1126. 17 May 2016

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M. and Wende, H. and Walcher, J. and Kühnemund, J. and Cheret, C. and Kempa, S. and McShane, E. and Selbach, M. and Lewin, G.R. and Birchmeier, C.
Genes & Development 32 (9-10): 645-657. 10 May 2018

Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Kirchner, F. and Schuetz, A. and Boldt, L.H. and Martens, K. and Dittmar, G. and Haverkamp, W. and Thierfelder, L. and Heinemann, U. and Gerull, B.
Circulation Cardiovascular Genetics 5 (4): 400-411. 1 August 2012

Developmental signaling in myocardial progenitor cells: A comprehensive view of Bmp- and Wnt/beta-catenin signaling.
Klaus, A. and Birchmeier, W.
Pediatric Cardiology 30 (5): 609-616. July 2009

Wnt signalling and its impact on development and cancer.
Klaus, A. and Birchmeier, W.
Nature Reviews Cancer 8 (5): 387-398. May 2008

Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.
Klaus, A. and Saga, Y. and Taketo, M.M. and Tzahor, E. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104 (47): 18531-18536. 20 November 2007

Hydrolysis of extracellular ATP by CD39+ Treg cells: context matters!
Kleinewietfeld, M. and Dimitri, D. and Sternjak, A. and Diamantini, A. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 111 (2): 965-966. 15 January 2008

CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T cell subset.
Kleinewietfeld, M. and Puentes, F. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 105 (7): 2877-2886. 1 January 2005

CD49d provides access to 'untouched' human Foxp3+ Treg free of contaminating effector cells.
Kleinewietfeld, M. and Starke, M. and Mitri, D.D. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 113 (4): 827-836. 22 January 2009

NF-κB activity is required for anagen maintenance in human hair follicles in vitro.
Kloepper, J.E. and Ernst, N. and Krieger, K. and Bodo, E. and Biro, T. and Haslam, I.S. and Schmidt-Ullrich, R. and Paus, R.
Journal of Investigative Dermatology 134 (7): 2036-2038. 11 February 2014

Structural investigation of glycan recognition by the ERAD quality control lectin Yos9.
Kniss, A. and Kazemi, S. and Löhr, F. and Berger, M. and Rogov, V.V. and Güntert, P. and Sommer, T. and Jarosch, E. and Dötsch, V.
Journal of Biomolecular NMR 72 (1-2): 1-10. October 2018

Chain assembly and disassembly processes differently affect the conformational space of ubiquitin chains.
Kniss, A. and Schuetz, D. and Kazemi, S. and Pluska, L. and Spindler, P.E. and Rogov, V.V. and Husnjak, K. and Dikic, I. and Güntert, P. and Sommer, T. and Prisner, T.F. and Dötsch, V.
Structure 26 (2): 249-258. 6 February 2018

Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: biphasic heat induction of cytosine deaminase suicide gene expression.
Kobelt, D. and Aumann, J. and Fichtner, I. and Stein, U. and Schlag, P.M. and Walther, W.
Molecular Biotechnology 46 (2): 197-205. October 2010

Performance of high quality minicircle DNA for in vitro and in vivo gene transfer.
Kobelt, D. and Schleef, M. and Schmeer, M. and Aumann, J. and Schlag, P.M. and Walther, W.
Molecular Biotechnology 53 (1): 80-89. January 2013

High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
Koechert, K. and Ullrich, K. and Kreher, S. and Aster, J.C. and Kitagawa, M. and Joehrens, K. and Anagnostopoulos, I. and Jundt, F. and Lamprecht, B. and Zimber-Strobl, U. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Oncogene 30 (15): 1831-1840. 14 April 2011

Crystal structure of KorA bound to operator DNA: insight into repressor cooperation in RP4 gene regulation.
Koenig, B. and Mueller, J.J. and Lanka, E. and Heinemann, U.
Nucleic Acids Research 37 (6): 1915-1924. April 2009

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. and Ofenbauer, A. and Bulut, S.I. and Uyar, B. and Baytek, G. and Sommermeier, A. and Seelk, S. and He, M. and Hirsekorn, A. and Vucicevic, D. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
Kolundzic, E. and Ofenbauer, A. and Uyar, B. and Sommermeier, A. and Seelk, S. and He, M. and Baytek, G. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
bioRxiv : 185116. 6 September 2017

Janggu: deep learning for genomics.
Kopp, W. and Monti, R. and Tamburrini, A. and Ohler, U. and Akalin, A.
bioRxiv : 700450. 16 July 2019

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S. and Bouhlel, M.A. and Cauchy, P. and Lamprecht, B. and Li, S. and Grau, M. and Hummel, F. and Köchert, K. and Anagnostopoulos, I. and Jöhrens, K. and Hummel, M. and Hiscott, J. and Wenzel, S.S. and Lenz, P. and Schneider, M. and Küppers, R. and Scheidereit, C. and Giefing, M. and Siebert, R. and Rajewsky, K. and Lenz, G. and Cockerill, P.N. and Janz, M. and Dörken, B. and Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111 (42): E4513-E4522. 21 October 2014

Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas.
Kretschmer, C. and Conradi, A. and Kemmner, W. and Sterner-Kock, A.
Cellular Oncology 34 (5): 419-434. 6 October 2011

NF-κB participates in mouse hair cycle control and plays distinct roles in the various pelage hair follicle types.
Krieger, K. and Millar, S.E. and Mikuda, N. and Krahn, I. and Kloepper, J.E. and Bertolini, M. and Scheidereit, C. and Paus, R. and Schmidt-Ullrich, R.
Journal of Investigative Dermatology 138 (2): 256-264. February 2018

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.
Kruschinski, A. and Moosmann, A. and Poschke, I. and Norell, H. and Chmielewski, M. and Seliger, B. and Kiessling, R. and Blankenstein, T. and Abken, H. and Charo, J.
Proceedings of the National Academy of Sciences of the United States of America 105 (45): 17481-17486. 11 November 2008

Computational approaches to discovering noncoding RNA.
Krzyzanowski, P.M. and Muro, E.M. and Andrade-Navarro, M.A.
Wiley Interdisciplinary Reviews: RNA 3 (4): 567-579. July 2012

Diversity in structure and function of tethering complexes: Evidence for different mechanisms in vesicular transport regulation.
Kuemmel, D. and Heinemann, U.
Current Protein & Peptide Science 9 (2): 197-209. April 2008

Unique self-palmitoylation activity of the transport protein particle component Bet3: A mechanism required for protein stability.
Kuemmel, D. and Heinemann, U. and Veit, M.
Proceedings of the National Academy of Sciences of the United States of America 103 (34): 12701-12706. 22 August 2006

Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2.
Kuemmel, D. and Mueller, J.J. and Roske, Y. and Henke, N. and Heinemann, U.
Journal of Molecular Biology 361 (1): 22-32. 4 August 2006

The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex.
Kuemmel, D. and Mueller, J.J. and Roske, Y. and Misselwitz, R. and Buessow, K. and Heinemann, U.
EMBO Reports 6 (8): 787-793. 6 August 2005

Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells.
Kuemmel, D. and Oeckinghaus, A. and Wang, C. and Krappmann, D. and Heinemann, U.
FEBS Letters 582 (27): 3729-3733. 12 November 2008

Structural studies of the human tethering complex TRAPP involved in vesicular transport.
Kuemmel, D. and Turnbull, A.P. and Mueller, J.J. and Roske, Y. and Heinemann, U.
2006

Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells.
Kuerbitz, C. and Heise, D. and Redmer, T. and Goumas, F. and Arlt, A. and Lemke, J. and Rimbach, G. and Kalthoff, H. and Trauzold, A.
Cancer Science 102 (4): 728-734. April 2011

Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury.
Kusch, A. and Hoff, U. and Bubalo, G. and Zhu, Y. and Fechner, M. and Schmidt-Ullrich, R. and Marko, L. and Müller, D.N. and Schmidt-Ott, K.M. and Guergen, D. and Blum, M. and Schunck, W.H. and Dragun, D.
Acta Physiologica 208 (1): 25-40. May 2013

Divergent transcription and epigenetic directionality of human promoters.
Lacadie, S.A. and Ibrahim, M.M. and Gokhale, S.A. and Ohler, U.
FEBS Journal 283 (23): 4214-4222. December 2016

Repeat-element driven activation of proto-oncogenes in human malignancies.
Lamprecht, B. and Bonifer, C. and Mathas, S.
Cell Cycle 9 (21): 4276-4281. November 2010

Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3α.
Lamprecht, B. and Kreher, S. and Anagnostopoulos, I. and Joehrens, K. and Monteleone, G. and Jundt, F. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Blood 112 (8): 3339-3347. 15 October 2008

The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome.
Lamprecht, B. and Kreher, S. and Moebs, M. and Sterry, W. and Doerken, B. and Janz, M. and Assaf, C. and Mathas, S.
British Journal of Dermatology 167 (2): 240-246. August 2012

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B. and Walter, K. and Kreher, S. and Kumar, R. and Hummel, M. and Lenze, D. and Koechert, K. and Bouhlel, M.A. and Richter, J. and Soler, E. and Stadhouders, R. and Joehrens, K. and Wurster, K.D. and Callen, D.F. and Harte, M.F. and Giefing, M. and Barlow, R. and Stein, H. and Anagnostopoulos, I. and Janz, M. and Cockerill, P.N. and Siebert, R. and Doerken, B. and Bonifer, C. and Mathas, S.
Nature Medicine 16 (5): 571-579, 1p following 579. May 2010

Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.
Lan, L. and Holland, J.D. and Qi, J. and Grosskopf, S. and Rademann, J. and Vogel, R. and Gyoerffy, B. and Wulf-Goldenberg, A. and Birchmeier, W.
EMBO Journal 34 (11): 1493-1508. 3 June 2015

Master and commander? FoxO's role in muscle atrophy.
Langer, H.T.
Journal of Physiology 595 (14): 4593-4594. 15 July 2017

Stomatin-domain proteins.
Lapatsina, L. and Brand, J. and Poole, K. and Daumke, O. and Lewin, G.R.
European Journal of Cell Biology 91 (4): 240-245. April 2012

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M. and Perrod, C. and Hoogenkamp, M. and Ghani, S. and Assi, S. and Heinz, S. and Wilson, N.K. and Follows, G. and Schoenheit, J. and Vockentanz, L. and Mosamam, A. and Chen, W. and Tenen, D.G. and Westhead, D.R. and Goettgens, B. and Bonifer, C. and Rosenbauer, F.
Blood 117 (10): 2827-2838. 10 March 2011

Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette.
Leisegang, M. and Engels, B. and Meyerhuber, P. and Kieback, E. and Sommermeyer, D. and Xue, S.A. and Reuss, S. and Stauss, H. and Uckert, W.
Journal of Molecular Medicine 86 (5): 573-583. May 2008

T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy.
Leisegang, M. and Turqueti-Neves, A. and Engels, B. and Blankenstein, T. and Schendel, D.J. and Uckert, W. and Noessner, E.
Clinical Cancer Research 16 (8): 2333-2343. 15 April 2010

MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors.
Leisegang, M. and Wilde, S. and Spranger, S. and Milosevic, S. and Frankenberger, B. and Uckert, W. and Schendel, D.J.
Journal of Clinical Investigation 120 (11): 3869-3877. 1 November 2010

MACC1 induces tumor progression in transgenic mice and colorectal cancer patients via increased pluripotency markers Nanog and Oct4.
Lemos, C. and Hardt, M.S. and Juneja, M. and Voss, C. and Foerster, S. and Jerchow, B. and Haider, W. and Blaker, H. and Stein, U.
Clinical Cancer Research 22 (11): 2812-2824. 1 June 2016

Anti-metastatic treatment in colorectal cancer: targeting signaling pathways.
Lemos, C. and Sack, U. and Schmid, F. and Juneja, M. and Stein, U.
Current Pharmaceutical Design 19 (5): 841-863. February 2013

Transgenic mice with a diverse human T cell antigen receptor repertoire.
Li, L.P. and Lampert, J.C. and Chen, X. and Leitao, C. and Popovic, J. and Mueller, W. and Blankenstein, T.
Nature Medicine 16 (9): 1029-1034. September 2010

A single TCRα-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire.
Liang, X. and Weigand, L.U. and Schuster, I.G. and Eppinger, E. and van der Griendt, J.C. and Schub, A. and Leisegang, M. and Sommermeyer, D. and Anderl, F. and Han, Y. and Ellwart, J. and Moosmann, A. and Busch, D.H. and Uckert, W. and Peschel, C. and Krackhardt, A.M.
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Immunotherapy of B cell non-Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model.
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Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.
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Science 356 (6335): 307-311. 21 April 2017

The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells.
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Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
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Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
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BioEssays 35 (6): 503-507. June 2013

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer, M. and Grau, M. and Lenze, D. and Wenzel, S.S. and Wolf, A. and Wollert-Wulf, B. and Dietze, K. and Nogai, H. and Storek, B. and Madle, H. and Dörken, B. and Janz, M. and Dirnhofer, S. and Lenz, P. and Hummel, M. and Tzankov, A. and Lenz, G.
Proceedings of the National Academy of Sciences of the United States of America 110 (30): 12420-12425. 23 July 2013

In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.
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Clinical and Experimental Metastasis 29 (6): 573-583. August 2012

Mutation analysis of BRCA1 and BRCA2 genes in Iranian high risk breast cancer families.
Pietschmann, A. and Mehdipour, P. and Mehdipour, P. and Atri, M. and Hofmann, W. and Hosseini-Asl, S. and Scherneck, S. and Mundlos, S. and Peters, H.
Journal of Cancer Research and Clinical Oncology 131 (8): 552-558. 1 January 2005

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M. and Glažar, P. and Hernandez-Miranda, L.R. and Memczak, S. and Wolf, S.A. and Rybak-Wolf, A. and Filipchyk, A. and Klironomos, F. and Cerda Jara, C.A. and Fenske, P. and Trimbuch, T. and Zywitza, V. and Plass, M. and Schreyer, L. and Ayoub, S. and Kocks, C. and Kühn, R. and Rosenmund, C. and Birchmeier, C. and Rajewsky, N.
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G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta.
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Journal of Biological Chemistry 283 (39): 26357-26363. 26 September 2008

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.
Poncette, L. and Chen, X. and Lorenz, F.K.M. and Blankenstein, T.
Journal of Clinical Investigation 129 (1): 324-335. 2 January 2019

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
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Blood 118 (4): 946-954. 28 July 2011

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
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Gut 65 (10): 1690-1701. October 2016

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.
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Cancer Letters 403 : 231-245. 10 September 2017

MACC1 - the first decade of a key metastasis molecule from gene discovery to clinical translation.
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Cancer and Metastasis Reviews 37 (4): 805-820. December 2018

Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity.
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E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
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EMBO Reports 12 (7): 720-726. 1 July 2011

Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
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Blood 118 (4): 1020-1033. 28 July 2011

Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
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Nature Communications 5 : 5057. 30 September 2014

Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence.
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Cancer Cell 17 (3): 262-272. 16 March 2010

Quantifying multi-layered expression regulation in response to stress of the endoplasmic reticulum.
Rendleman, J. and Cheng, Z. and Maity, S. and Kastelic, N. and Munschauer, M. and Allgoewer, K. and Teo, G. and Zhang, Y.B. and Lei, A. and Parker, B. and Landthaler, M. and Freeberg, L. and Kuersten, S. and Choi, H. and Vogel, C.
bioRxiv : 308379. 25 April 2018

New insights into the cellular temporal response to proteostatic stress.
Rendleman, J. and Cheng, Z. and Maity, S. and Kastelic, N. and Munschauer, M. and Allgoewer, K. and Teo, G. and Zhang, Y.B.M. and Lei, A. and Parker, B. and Landthaler, M. and Freeberg, L. and Kuersten, S. and Choi, H. and Vogel, C.
eLife 7 : e39054. 12 October 2018

Suspension packaging cell lines for the simplified generation of T-cell receptor encoding retrovirus vector particles.
Reuss, S. and Biese, P. and Cosset, F.L. and Takeuchi, Y. and Uckert, W.
Gene Therapy 14 (7): 595-603. April 2007

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors.
Richter, M. and Saydaminova, K. and Yumul, R. and Krishnan, R. and Liu, J. and Nagy, E.E. and Singh, M. and Izsvák, Z. and Cattaneo, R. and Uckert, W. and Palmer, D. and Ng, P. and Haworth, K.G. and Kiem, H.P. and Ehrhardt, A. and Papayannopoulou, T. and Lieber, A.
Blood 128 (18): 2206-2217. 3 November 2016

In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.
Roetzschke, O. and Borsellino, G. and Battistini, L. and Falk, K. and Kleinewietfeld, M.
Blood 113 (9): 2119-2120. 26 February 2009

Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies.
Rohr, U.P. and Herrmann, P. and Ilm, K. and Zhang, H. and Lohmann, S. and Reiser, A. and Muranyi, A. and Smith, J. and Burock, S. and Osterland, M. and Leith, K. and Singh, S. and Brunhoeber, P. and Bowermaster, R. and Tie, J. and Christie, M. and Wong, H.L. and Waring, P. and Shanmugam, K. and Gibbs, P. and Stein, U.
Annals of Oncology 28 (8): 1869-1875. 1 August 2017

Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB.
Rohwer, N. and Dame, C. and Haugstetter, A.M. and Wiedenmann, B. and Detjen, K. and Schmitt, C.A. and Cramer, T.
PLoS ONE 5 (8): e12038. 10 August 2010

Non-canonical HIF-1 stabilization is essential for intestinal tumorigenesis.
Rohwer, N. and Jumpertz, S. and Erdem, M. and Egners, A. and Warzecha, K.T. and Fragoulis, A. and Kuehl, A.A. and Kramann, R. and Neuss, S. and Rudolph, I. and Endermann, T. and Zasada, C. and Apostolova, I. and Gerling, M. and Kempa, S. and Hughes, R. and Lewis, C.E. and Brenner, W. and Malinowski, M.B. and Stockmann, M. and Schomburg, L. and Faller, W. and Sansom, O.J. and Tacke, F. and Morkel, M. and Cramer, T.
bioRxiv : 273045. 28 February 2018

Response of patient-derived non-small cell lung cancer xenografts to classical and targeted therapies is not related to multidrug resistance markers.
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IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis.
Rothe, M. and Quarcoo, D. and Chashchina, A.A. and Bozrova, S.V. and Qin, Z. and Nedospasov, S.A. and Blankenstein, T. and Kammertoens, T. and Drutskaya, M.S.
Cancer Medicine 2 (6): 815-825. December 2013

CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A. and Qadri, F. and Leukel, L. and Yilmaz, R. and Fontaine, J.F. and Sihn, G. and Bader, M. and Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123 (3): 1343-1347. 1 March 2013

The answer's in the tail: MYC mRNA has a metabolic sensor that supports cancer chemoresistance.
Royla, N. and Kempa, S.
Molecular & Cellular Oncology 4 (4): e1338209. 5 July 2017

The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.
Rueder, C. and Hoepken, U.E. and Wolf, J. and Mittruecker, H.W. and Engels, B. and Erdmann, B. and Wollenzin, S. and Uckert, W. and Doerken, B. and Rehm, A.
Journal of Clinical Investigation 119 (8): 2184-2203. August 2009

Wnt up your mind - intervention strategies for S100A4-induced metastasis in colon cancer.
Sack, U. and Stein, U.
General Physiology and Biophysics 28 (Focus Iss): F55-F64. December 2009

S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells.
Sack, U. and Walther, W. and Scudiero, D. and Selby, M. and Aumann, J. and Lemos, C. and Fichtner, I. and Schlag, P.M. and Shoemaker, R.H. and Stein, U.
Molecular Biology of the Cell 22 (18): 3344-3354. September 2011

Novel effect of antihelminthic niclosamide on S100A4-mediated metastatic progression in colon cancer.
Sack, U. and Walther, W. and Scudiero, D. and Selby, M. and Kobelt, D. and Lemm, M. and Fichtner, I. and Schlag, P.M. and Shoemaker, R.H. and Stein, U.
Journal of the National Cancer Institute 103 (13): 1018-1036. 6 July 2011

Suppression of polyploidy by the BRCA2 protein.
Sagulenko, E. and Savelyeva, L. and Ehemann, V. and Sagulenko, V. and Hofmann, W. and Arnold, K. and Claas, A. and Scherneck, S. and Schwab, M.
Cancer Letters 257 (1): 65-72. 8 November 2007

Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.
Sander, S. and Calado, D.P. and Srinivasan, L. and Köchert, K. and Zhang, B. and Rosolowski, M. and Rodig, S.J. and Holzmann, K. and Stilgenbauer, S. and Siebert, R. and Bullinger, L. and Rajewsky, K.
Cancer Cell 22 (2): 167-179. 14 August 2012

PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones.
Sander, S. and Chu, V.T. and Yasuda, T. and Franklin, A. and Graf, R. and Calado, D.P. and Li, S. and Imami, K. and Selbach, M. and Di Virgilio, M. and Bullinger, L. and Rajewsky, K.
Immunity 43 (6): 1075-1086. 15 December 2015

Constitutional genomic instability with inversions, duplications, and amplifications in 9p23-24 in BRCA2 mutation carriers.
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Cancer Research 61 : 5179-5185. 1 January 2001

Loss of Gadkin affects dendritic cell migration in vitro.
Schachtner, H. and Weimershaus, M. and Stache, V. and Plewa, N. and Legler, D.F. and Höpken, U.E. and Maritzen, T.
PLoS ONE 10 (12): e0143883. 1 December 2015

HIPPIE: integrating protein interaction networks with experiment based quality scores.
Schaefer, M.H. and Fontaine, J.F. and Vinayagam, A. and Porras, P. and Wanker, E.E. and Andrade-Navarro, M.A.
PLoS ONE 7 (2): e31826. 14 February 2012

Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.
Schaefer, M.H. and Lopes, T.J.S. and Mah, N. and Shoemaker, J.E. and Matsuoka, Y. and Fontaine, J.F. and Louis-Jeune, C. and Eisfeld, A.J. and Neumann, G. and Perez-Iratxeta, C. and Kawaoka, Y. and Kitano, H. and Andrade-Navarro, M.A.
PLoS Computational Biology 9 (1): e1002860. 3 January 2013

Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Schaefer, M.H. and Wanker, E.E. and Andrade-Navarro, M.A.
Nucleic Acids Research 40 (10): 4273-4287. 1 May 2012

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Schaeper, U. and Vogel, R. and Chmielowiec, J. and Huelsken, J. and Rosario, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104 (39): 15376-15381. 25 September 2007

Vectors for co-expression of an unrestricted number of proteins.
Scheich, C. and Kuemmel, D. and Soumailakakis, D. and Heinemann, U. and Buessow, K.
Nucleic Acids Research 35 (6): e43. March 2007

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Schleussner, N. and Merkel, O. and Costanza, M. and Liang, H.C. and Hummel, F. and Romagnani, C. and Durek, P. and Anagnostopoulos, I. and Hummel, M. and Jöhrens, K. and Niedobitek, A. and Griffin, P.R. and Piva, R. and Sczakiel, H.L. and Woessmann, W. and Damm-Welk, C. and Hinze, C. and Stoiber, D. and Gillissen, B. and Turner, S.D. and Kaergel, E. and von Hoff, L. and Grau, M. and Lenz, G. and Dörken, B. and Scheidereit, C. and Kenner, L. and Janz, M. and Mathas, S.
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Peptide linkage to the α-subunit of MHCII creates a stably inverted antigen presentation complex.
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Journal of Molecular Biology 423 (3): 294-302. 26 October 2012

A xenon-129 biosensor for monitoring MHC-peptide interactions.
Schlundt, A. and Kilian, W. and Beyermann, M. and Sticht, J. and Guenther, S. and Hoepner, S. and Falk, K. and Roetzschke, O. and Mitschang, L. and Freund, C.
Angewandte Chemie International Edition 48 (23): 4142-4145. 25 May 2009

SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer.
Schmid, F. and Burock, S. and Klockmeier, K. and Schlag, P.M. and Stein, U.
Molecular Cancer 11 (1): 49. 29 July 2012

Use of Kaede fusions to visualize recycling of G protein-coupled receptors.
Schmidt, A. and Wiesner, B. and Weisshart, K. and Schulz, K. and Furkert, J. and Lamprecht, B. and Rosenthal, W. and Schuelein, R.
Traffic 10 (1): 2-15. January 2009

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
Schmidt, K. and Zilio, S. and Schmollinger, J.C. and Bronte, V. and Blankenstein, T. and Willimsky, G.
Blood 121 (10): 1740-1748. 7 March 2013

NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.
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Development 133 (6): 1045-1057. 15 March 2006

Dysferlin-peptides reallocate mutated dysferlin thereby restoring function.
Schoewel, V. and Marg, A. and Kunz, S. and Overkamp, T. and Siegert Carrazedo, R. and Zacharias, U. and Daniel, P.T. and Spuler, S.
PLoS ONE 7 (11): e49603. 20 November 2012

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
Schrade, K. and Tröger, J. and Eldahshan, A. and Zühlke, K. and Abdul Azeez, K.R. and Elkins, J.M. and Neuenschwander, M. and Oder, A. and Elkewedi, M.M.H. and Jaksch, S. and Andrae, K. and Li, J. and Fernandes, J. and Müller, P.M. and Grunwald, S. and Marino, S.F. and Vukićević, T. and Eichhorst, J. and Wiesner, B. and Weber, M. and Kapiloff, M. and Rocks, O. and Daumke, O. and Wieland, T. and Knapp, S. and von Kries, J.P. and Klussmann, E.
PLoS ONE 13 (1): e0191423. 26 January 2018

Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis.
Schreiber, T. and Ehlers, S. and Aly, S. and Hoelscher, A. and Hartmann, S. and Lipp, M. and Lowe, J.B. and Hoelscher, C.
Journal of Immunology 176 (2): 1131-1140. 15 January 2006

Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures.
Schroeder, M.P. and Bastian, L. and Eckert, C. and Gökbuget, N. and James, A.R. and Ortiz Tanchez, J. and Schlee, C. and Isaakidis, K. and Häupl, B. and Baum, K. and Migueles Lozano, O.A. and Kouidri, K. and Pan, K.T. and Urlaub, H. and Schwartz, S. and Burmeister, T. and von Stackelberg, A. and Hoelzer, D. and Pfeiffer, H. and Rieger, M.A. and Göllner, S. and Oellerich, T. and Horstman, M. and Schrappe, M. and Wolf, J. and Kirschner-Schwabe, R. and Brüggemann, M. and Müller-Tidow, C. and Serve, H. and Neumann, M. and Baldus, C.D.
Scientific Reports 9 (1): 4188. 12 March 2019

Roquin binding to target mRNAs involves a winged helix-turn-helix motif.
Schuetz, A. and Murakawa, Y. and Rosenbaum, E. and Landthaler, M. and Heinemann, U.
Nature Communications 5 : 5701. 11 December 2014

The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion.
Schulte, K. and Pawlowski, N. and Faelber, K. and Fröhlich, C. and Howard, J. and Daumke, O.
BMC Biology 14 (1): 14. 2 March 2016

Structural basis for aryl hydrocarbon receptor-mediated gene activation.
Schulte, K.W. and Green, E. and Wilz, A. and Platten, M. and Daumke, O.
Structure 25 (7): 1025-1033. 5 July 2017

Activation-dependent TRAF3 exon 8 alternative splicing is controlled by CELF2 and hnRNP C binding to an upstream intronic element.
Schultz, A.S. and Preussner, M. and Bunse, M. and Karni, R. and Heyd, F.
Molecular and Cellular Biology 37 (7): e.00488-16. April 2017

CCR7 deficiency causes diarrhea associated with altered ion transport in colonocytes in the absence of overt colitis.
Schumann, M. and Winter, S. and Wichner, K. and May, C. and Kuehl, A.A. and Batra, A. and Siegmund, B. and Zeitz, M. and Schulzke, J.D. and Lipp, M. and Hoepken, U.E.
Mucosal Immunology 5 (4): 377-387. July 2012

Global analysis of cellular protein translation by pulsed SILAC.
Schwanhaeusser, B. and Gossen, M. and Dittmar, G. and Selbach, M.
Proteomics 9 (1): 205-209. January 2009

Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model.
Schwarzer, R. and Nickel, N. and Godau, J. and Willie, B.M. and Duda, G.N. and Schwarzer, R. and Cirovic, B. and Leutz, A. and Manz, R. and Bogen, B. and Dörken, B. and Jundt, F.
Blood Cancer Journal 4 : e217. 13 June 2014

GTP-dependent scaffold formation in the GTPase of Immunity Associated Protein family.
Schwefel, D. and Daumke, O.
Small GTPases 2 (1): 27-30. January 2011

Purification, crystallization and preliminary X-ray analysis of human GIMAP2.
Schwefel, D. and Froehlich, C. and Daumke, O.
Acta Crystallographica Section F 66 (6): 725-729. 1 June 2010

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Schwefel, D. and Froehlich, C. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Aravind, L. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 107 (47): 20299-20304. 23 November 2010

Quantitative analysis of EBV-specific CD4/CD8 T cell numbers, absolute CD4/CD8 T cell numbers and EBV load in solid organ transplant recipients with PLTD.
Sebelin-Wulf, K. and Nguyen, T.D. and Oertel, S. and Papp-Vary, M. and Trappe, R. and Schulzki, A. and Pezzutto, A. and Riess, H. and Subklewe, M.
Transplant Immunology 17 (3): 203-210. April 2007

Transmitter- and hormone-activated Ca(2+) responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca(2+) sensor.
Seifert, S. and Pannell, M. and Uckert, W. and Faerber, K. and Kettenmann, H.
Cell Calcium 49 (6): 365-375. June 2011

Host cell interactome of tyrosine-phosphorylated bacterial proteins.
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Cell Host & Microbe 5 (4): 397-403. 23 April 2009

Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Serresi, M. and Siteur, B. and Hulsman, D. and Company, C. and Schmitt, M.J. and Lieftink, C. and Morris, B. and Cesaroni, M. and Proost, N. and Beijersbergen, R.L. and van Lohuizen, M. and Gargiulo, G.
Journal of Experimental Medicine 215 (12): 3115. 3 December 2018

Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C. and Hegde, B.G. and Morén, B. and Behrmann, E. and Mielke, T. and Moenke, G. and Spahn, C.M. and Lundmark, R. and Daumke, O. and Langen, R.
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The primary transcriptome of barley chloroplasts: numerous noncoding RNAs and the dominating role of the plastid-encoded RNA polymerase.
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Subcutaneous adipose tissue-derived stem cells: advancement and applications in regenerative medicine.
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The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation.
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SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations.
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The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
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Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
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Abdelilah-Seyfried, Salim

Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
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Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
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Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling.
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Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets via protocol-specific bias modeling.
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FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
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Developmental Cell 46 (5): 611-626. 10 September 2018

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
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Janggu: deep learning for genomics.
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Degrons in cancer.
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Mutations in disordered regions can cause disease by creating dileucine motifs.
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Cell 175 (1): 239-253. 20 September 2018

Mutations in disordered regions cause disease by creating endocytosis motifs.
Meyer, K. and Uyar, B. and Kirchner, M. and Cheng, J. and Akalin, A. and Selbach, M.
bioRxiv : 141622. 24 May 2017

The IκB kinase complex is a regulator of mRNA stability.
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EMBO Journal 37 (24): e98658. 14 December 2018

The conserved histone chaperone LIN-53 links lifespan and healthspan regulation in C. elegans.
Muethel, S. and Uyar, B. and He, M. and Krause, A. and Vitrinel, B. and Bulut, S. and Vasiljevic, D. and Akalin, A. and Kempa, S. and Tursun, B.
bioRxiv : 539015. 2 February 2019

Deciphering human ribonucleoprotein regulatory networks.
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Nucleic Acids Research 47 (2): 570-581. 25 January 2019

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
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Aging Cell : e13012. 9 August 2019 (In Press)

RCAS: an RNA centric annotation system for transcriptome-wide regions of interest.
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Nucleic Acids Research 45 (10): e91. 2 June 2017

Global identification of functional microRNA-mRNA interactions in Drosophila.
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Nature Communications 10 (1): 1626. 9 April 2019

Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.
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Genome Biology 18 (1): 209. 31 October 2017

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L. and Kärgel, E. and Franke, V. and McShane, E. and Schulz-Beiss, K.W. and Patone, G. and Schleussner, N. and Kolesnichenko, M. and Hübner, N. and Daumke, O. and Selbach, M. and Akalin, A. and Mathas, S. and Scheidereit, C.
Blood 133 (13): 1489-1494. 28 March 2019

Alexander, Christiane

Characterization of protein-binding to the spinach chloroplast psbA mRNA 5' untranslated region.
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Nucleic Acids Research 26 (10): 2265-2272. 15 May 1998

Andrade Navarro, Miguel

Mining the literature: new methods to exploit keyword profiles.
Andrade-Navarro, M.A.
Genome Medicine 4 (10): 81. 30 October 2012

A method for cell type marker discovery by high-throughput gene expression analysis of mixed cell populations.
Andrade-Navarro, M.A. and Kanji, F. and Palii, C.G. and Brand, M. and Atkins, H. and Perez-Iratxeta, C.
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Peer2ref: a peer-reviewer finding web tool that uses author disambiguation.
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PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries.
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PRC1-mediated gene silencing in pluripotent ES cells: function and evolution.
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CAFE: an R package for the detection of gross chromosomal abnormalities from gene expression microarray data.
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Bioinformatics 30 (10): 1484-1485. 15 May 2014

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, A.M. and Vockentanz, L. and Kharazi, S. and Huska, M.R. and Mancini, E. and Scheller, M. and Kuhl, C. and Enns, A. and Prinz, M. and Jaenisch, R. and Nerlov, C. and Leutz, A. and Andrade-Navarro, M.A. and Jacobsen, S.E. and Rosenbauer, F.
Nature Genetics 41 (11): 1207-1215. November 2009

Arabidopsis KCBP interacts with AIR9 but stays in the cortical division zone throughout mitosis via its MyTH4-FERM domain.
Buschmann, H. and Dols, J. and Kopischke, S. and Pena, E.J. and Andrade-Navarro, M.A. and Heinlein, M. and Szymanski, D.B. and Zachgo, S. and Doonan, J.H. and Lloyd, C.W.
Journal of Cell Science 28 (11): 2033-2046. 1 June 2015

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N. and Naumann, H. and Ruzittu, S. and Mah, N. and Pongrac, I.M. and Cozzitorto, C. and Hommel, A. and Andrade-Navarro, M.A. and Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8 : 14127. 13 February 2017

Identification of 2-[4-[(4-methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers.
Cheng, X. and Dimou, E. and Alborzinia, H. and Wenke, F. and Goehring, A. and Reuter, S. and Mah, N. and Fuchs, H. and Andrade-Navarro, M.A. and Adjaye, J. and Gul, S. and Harms, C. and Utikal, J. and Klipp, E. and Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58 (12): 4976-4983. 25 June 2015

Ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4.
Cheng, X. and Yoshida, H. and Raoofi, D. and Saleh, S. and Alborzinia, H. and Wenke, F. and Goehring, A. and Reuter, S. and Mah, N. and Fuchs, H.R. and Andrade-Navarro, M.A. and Adjaye, J. and Gul, S. and Utikal, J. and Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58 (1): 5742-5750. 13 August 2015

Preimplantation development regulatory pathway construction through a text-mining approach.
Donnard, E. and Barbosa-Silva, A. and Guedes, R.L. and Fernandes, G.R. and Velloso, H. and Kohn, M.J. and Andrade-Navarro, M.A. and Ortega, J.M.
BMC Genomics 12 (Suppl 4): S3. 22 December 2011

Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma.
Fehlker, M. and Huska, M.R. and Joens, T. and Andrade-Navarro, M.A. and Kemmner, W.
BMC Cancer 14 (1): 64. 5 February 2014

Assessment of curated phenotype mining in neuropsychiatric disorder literature.
Fontaine, J.F. and Priller, J. and Spruth, E. and Perez-Iratxeta, C. and Andrade-Navarro, M.A.
Methods 74 : 90-96. March 2015

PDBpaint, a visualization webservice to tag protein structures with sequence annotations.
Fournier, D. and Andrade-Navarro, M.A.
Bioinformatics 27 (18): 2605-2606. 15 September 2011

Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D. and Luft, F.C. and Bader, M. and Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90 (5): 495-508. May 2012

Functional and genomic analyses of α-solenoid proteins.
Fournier, D. and Palidwor, G.A. and Shcherbinin, S. and Szengel, A. and Schaefer, M.H. and Perez-Iratxeta, C. and Andrade-Navarro, M.A.
PLoS ONE 8 (11): e79894. 21 November 2013

mBISON: Finding miRNA target over-representation in gene lists from ChIP-sequencing data.
Gebhardt, M.L. and Mer, A.S. and Andrade-Navarro, M.A.
BMC Research Notes 8 (1): 157. 16 April 2015

Similarity in targets with REST points to neural and glioblastoma related miRNAs.
Gebhardt, M.L. and Reuter, S. and Mrowka, R. and Andrade-Navarro, M.A.
Nucleic Acids Research 42 (9): 5436-5446. 14 May 2014

Alkemio: association of chemicals with biomedical topics by text and data mining.
Gijon-Correas, J.A. and Andrade-Navarro, M.A. and Fontaine, J.F.
Nucleic Acids Research 42 (W1): W422-W429. 1 July 2014

Bio++: efficient extensible libraries and tools for computational molecular evolution.
Gueguen, L. and Gaillard, S. and Boussau, B. and Gouy, M. and Groussin, M. and Rochette, N.C. and Bigot, T. and Fournier, D. and Pouyet, F. and Cahais, V. and Bernard, A. and Scornavacca, C. and Nabholz, B. and Haudry, A. and Dachary, L. and Galtier, N. and Belkhir, K. and Dutheil, J.Y.
Molecular Biology and Evolution 30 (8): 1745-1750. August 2013

Alterations of pre-mRNA splicing in human inflammatory bowel disease.
Haesler, R. and Kerick, M. and Mah, N. and Hultschig, C. and Richter, G. and Bretz, F. and Sina, C. and Lehrach, H. and Nietfeld, W. and Schreiber, S. and Rosenstiel, P.
European Journal of Cell Biology 90 (6-7): 603-611. June 2011

A role for GPx3 in activity of normal and leukemia stem cells.
Herault, O. and Hope, K.J. and Deneault, E. and Mayotte, N. and Chagraoui, J. and Wilhelm, B.T. and Cellot, S. and Sauvageau, M. and Andrade-Navarro, M.A. and Hebert, J. and Sauvageau, G.
Journal of Experimental Medicine 209 (5): 895-901. 7 May 2012

DNA microarray and miRNA analyses reinforce the classification of follicular thyroid tumors.
Jacques, C. and Guillotin, D. and Fontaine, J.F. and Franc, B. and Mirebeau-Prunier, D. and Fleury, A. and Malthiery, Y. and Savagner, F.
Journal of Clinical Endocrinology and Metabolism 98 (5): E981-E989. May 2013

Computational approaches to discovering noncoding RNA.
Krzyzanowski, P.M. and Muro, E.M. and Andrade-Navarro, M.A.
Wiley Interdisciplinary Reviews: RNA 3 (4): 567-579. July 2012

A customized class of functions for modeling and clustering gene expression profiles in embryonic stem cells.
Li, S. and Andrade-Navarro, M. and Sankoff, D.
Lecture Notes in Computer Science 5167 : 92-103. 2008

Tissue specific subnetworks and characteristics of publicly available human protein interaction databases.
Lopes, T.J. and Schaefer, M. and Shoemaker, J. and Matsuoka, Y. and Fontaine, J.F. and Neumann, G. and Andrade-Navarro, M.A. and Kawaoka, Y. and Kitano, H.
Bioinformatics 27 (17): 2414-2421. 1 September 2011

Prediction of protein secondary structure from circular dichroism using theoretically derived spectra.
Louis-Jeune, C. and Andrade-Navarro, M.A. and Perez-Iratxeta, C.
Proteins: Structure, Function, and Bioinformatics 80 (2): 374-381. February 2012

In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans.
Ma, L. and Tan, Z. and Teng, Y. and Hoersch, S. and Horvitz, H.R.
RNA 17 (12): 2201-2211. December 2011

A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in caenorhabditis elegans.
Mansisidor, A.R. and Cecere, G. and Hoersch, S. and Jensen, M.B. and Kawli, T. and Kennedy, L.M. and Chavez, V. and Tan, M.W. and Lieb, J.D. and Grishok, A.
PLoS Genetics 7 (9): e1002299. September 2011

Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.
McNeill, B. and Perez-Iratxeta, C. and Mazerolle, C. and Furimsky, M. and Mishina, Y. and Andrade-Navarro, M.A. and Wallace, V.A.
Molecular and Cellular Neuroscience 49 (3): 333-340. March 2012

A novel approach for protein subcellular location prediction using amino acid exposure.
Mer, A.S. and Andrade-Navarro, M.A.
BMC Bioinformatics 14 (1): 342. 28 November 2013

Estrogen-related receptor alpha modulates lactate dehydrogenase activity in thyroid tumors.
Mirebeau-Prunier, D. and Le Pennec, S. and Jacques, C. and Fontaine, J.F. and Gueguen, N. and Boutet-Bouzamondo, N. and Donnart, A. and Malthiery, Y. and Savagner, F.
PLoS ONE 8 (3): e58683. 13 March 2013

Natural antisense transcripts within pseudogenes: an EST survey.
Muro, E.M. and Andrade-Navarro, M.A.
In: Non-coding RNAs and epigenetic regulation of gene expression : drivers of natural selection. Caister Academic Press (U.K.), Norfolk, 99-108. ISBN 978-1-904455-94-3 February 2012

Functional evidence of post-transcriptional regulation by pseudogenes.
Muro, E.M. and Mah, N. and Andrade-Navarro, M.A.
Biochimie 93 (11): 1916-1921. November 2011

The pseudogenes of Mycobacterium leprae reveal the functional relevance of gene order within operons.
Muro, E.M. and Mah, N. and Moreno-Hagelsieb, G. and Andrade-Navarro, M.A.
Nucleic Acids Research 39 (5): 1732-1738. 1 March 2011

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Naba, A. and Clauser, K.R. and Hoersch, S. and Liu, H. and Carr, S.A. and Hynes, R.O.
Molecular & Cellular Proteomics 11 (4): M111.014647. 1 April 2012

Preliminary evaluation of the CellFinder literature curation pipeline for gene expression in kidney cells and anatomical parts.
Neves, M. and Damaschun, A. and Mah, N. and Lekschas, F. and Seltmann, S. and Stachelscheid, H. and Fontaine, J.F. and Kurtz, A. and Leser, U.
Database 2013 (2013): bat020. 18 April 2013

ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics.
Norton, M. and Ng, A.C. and Baird, S. and Dumoulin, A. and Shutt, T. and Mah, N. and Andrade-Navarro, M.A. and McBride, H.M. and Screaton, R.A.
Science Signaling 7 (310): ra10. 28 January 2014

Using cited references to improve the retrieval of related biomedical documents.
Ortuno, F.M. and Rojas, I. and Andrade-Navarro, M.A. and Fontaine, J.F.
BMC Bioinformatics 14 : 113. 27 March 2013

A reference guide for tree analysis and visualization.
Pavlopoulos, G.A. and Soldatos, T.G. and Barbosa-Silva, A. and Schneider, R.
BioData Mining 3 : 1. 22 February 2010

Towards completion of the Earth's proteome.
Perez-Iratxeta, C. and Palidwor, G. and Andrade-Navarro, M.A.
EMBO Reports 8 (12): 1135-1141. 1 December 2007

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
Petrakis, S. and Rasko, T. and Russ, J. and Friedrich, R.P. and Stroedicke, M. and Riechers, S.P. and Muehlenberg, K. and Moeller, A. and Reinhardt, A. and Vinayagam, A. and Schaefer, M.H. and Boutros, M. and Tricoire, H. and Andrade-Navarro, M.A. and Wanker, E.E.
PLoS Genetics 8 (8): e1002897. 16 August 2012

Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
Petrakis, S. and Schaefer, M.H. and Wanker, E.E. and Andrade-Navarro, M.A.
BioEssays 35 (6): 503-507. June 2013

Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.
Riemke, P. and Czeh, M. and Fischer, J. and Walter, C. and Ghani, S. and Zepper, M. and Agelopoulos, K. and Lettermann, S. and Gebhardt, M.L. and Mah, N. and Weilemann, A. and Grau, M. and Groening, V. and Haferlach, T. and Lenze, D. and Delwel, R. and Prinz, M. and Andrade-Navarro, M.A. and Lenz, G. and Dugas, M. and Mueller-Tidow, C. and Rosenbauer, F.
EMBO Journal 35 (22): 2399-2416. 15 November 2016

CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A. and Qadri, F. and Leukel, L. and Yilmaz, R. and Fontaine, J.F. and Sihn, G. and Bader, M. and Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123 (3): 1343-1347. 1 March 2013

The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily.
Sanchez-Pulido, L. and Andrade-Navarro, M.A.
BMC Biochemistry 8 : 23. 8 November 2007

Paired sage-microarray expression data sets reveal antisense transcripts differentially expressed in embryonic stem cell differentiation.
Sandie, R. and Porter, C.J. and Palidwor, G.A. and Price, F. and Krzyzanowski, P.M. and Muro, E.M. and Hoersch, S. and Smith, M. and Campbell, P.A. and Perez-Iratxeta, C. and Rudnicki, M.A. and Andrade-Navarro, M.A.
In: Computational Biology of Embryonic Stem Cells. Bentham Science (U.S.A.), Oak Park, 193-215. ISBN 978-1-608-05025-3 2012

HIPPIE: integrating protein interaction networks with experiment based quality scores.
Schaefer, M.H. and Fontaine, J.F. and Vinayagam, A. and Porras, P. and Wanker, E.E. and Andrade-Navarro, M.A.
PLoS ONE 7 (2): e31826. 14 February 2012

Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.
Schaefer, M.H. and Lopes, T.J.S. and Mah, N. and Shoemaker, J.E. and Matsuoka, Y. and Fontaine, J.F. and Louis-Jeune, C. and Eisfeld, A.J. and Neumann, G. and Perez-Iratxeta, C. and Kawaoka, Y. and Kitano, H. and Andrade-Navarro, M.A.
PLoS Computational Biology 9 (1): e1002860. 3 January 2013

Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Schaefer, M.H. and Wanker, E.E. and Andrade-Navarro, M.A.
Nucleic Acids Research 40 (10): 4273-4287. 1 May 2012

SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.
Schmid, F. and Wang, Q. and Huska, M.R. and Andrade-Navarro, M.A. and Lemm, M. and Fichtner, I. and Dahlmann, M. and Kobelt, D. and Walther, W. and Smith, J. and Schlag, P.M. and Stein, U.
Oncogene 35 (46): 5942-5952. 17 November 2016

PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.
Schönheit, J. and Kuhl, C. and Gebhardt, M.L. and Klett, F.F. and Riemke, P. and Scheller, M. and Huang, G. and Naumann, R. and Leutz, A. and Stocking, C. and Priller, J. and Andrade-Navarro, M.A. and Rosenbauer, F.
Cell Reports 3 (5): 1617-1628. 30 May 2013

CELDA - an ontology for the comprehensive representation of cells in complex systems.
Seltmann, S. and Stachelscheid, H. and Damaschun, A. and Jansen, L. and Lekschas, F. and Fontaine, J.F. and Nguyen-Dobinsky, T.N. and Leser, U. and Kurtz, A.
BMC Bioinformatics 14 : 228. 17 July 2013

Comparison of inter- and intraspecies variation in humans and fruit flies.
Shih, J. and Hodge, R. and Andrade-Navarro, M.A.
Genomics Data 3 : 49-54. March 2015

Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a piwi protein.
Simon, B. and Kirkpatrick, J.P. and Eckhardt, S. and Reuter, M. and Rocha, E.A. and Andrade-Navarro, M.A. and Sehr, P. and Pillai, R.S. and Carlomagno, T.
Structure 19 (2): 172-180. 9 February 2011

Caipirini: using gene sets to rank literature.
Soldatos, T.G. and O'Donoghue, S.I. and Satagopam, V.P. and Barbosa-Silva, A. and Pavlopoulos, G.A. and Wanderley-Nogueira, A.C. and Soares-Cavalcanti, N.M. and Schneider, R.
BioData Mining 5 (1): 1. 1 February 2012

CellFinder: a cell data repository.
Stachelscheid, H. and Seltmann, S. and Lekschas, F. and Fontaine, J.F. and Mah, N. and Neves, M. and Andrade-Navarro, M.A. and Leser, U. and Kurtz, A.
Nucleic Acids Research 42 (1): D950-D958. 1 January 2014

Armadillo motifs involved in vesicular transport.
Striegl, H. and Andrade-Navarro, M.A. and Heinemann, U.
PLoS ONE 5 (2): e8991. 1 February 2010

Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke, M. and Bounab, Y. and Strempel, N. and Klockmeier, K. and Yigit, S. and Friedrich, R.P. and Chaurasia, G. and Li, S. and Hesse, F. and Riechers, S.P. and Russ, J. and Nicoletti, C. and Boeddrich, A. and Wiglenda, T. and Haenig, C. and Schnoegl, S. and Fournier, D. and Graham, R.K. and Hayden, M.R. and Sigrist, S. and Bates, G.P. and Priller, J. and Andrade-Navarro, M.A. and Futschik, M.E. and Wanker, E.E.
Genome Research 25 (5): 701-713. May 2015

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
Suratanee, A. and Schaefer, M.H. and Betts, M.J. and Soons, Z. and Mannsperger, H. and Harder, N. and Oswald, M. and Gipp, M. and Ramminger, E. and Marcus, G. and Männer, R. and Rohr, K. and Wanker, E. and Russell, R.B. and Andrade-Navarro, M.A. and Eils, R. and König, R.
PLoS Computational Biology 10 (9): e1003814. 25 September 2014

Development and application of a DNA microarray-based yeast two-hybrid system.
Suter, B. and Fontaine, J.F. and Yildirimman, R. and Raskó, T. and Schaefer, M.H. and Rasche, A. and Porras, P. and Vázquez-Álvarez, B.M. and Russ, J. and Rau, K. and Foulle, R. and Zenkner, M. and Saar, K. and Herwig, R. and Andrade-Navarro, M.A. and Wanker, E.E.
Nucleic Acids Research 41 (3): 1496-507. 1 February 2013

Short tandem repeats in the inhibitory domain of the mineralocorticoid receptor: prediction of a β-solenoid structure.
Vlassi, M. and Brauns, K. and Andrade-Navarro, M.A.
BMC Structural Biology 13 (1): 17. 2 October 2013

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K. and Ullrich, F. and Muench, J. and Lazarow, K. and Lutter, D. and Mah, N. and Andrade-Navarro, M.A. and von Kries, J.P. and Stauber, T. and Jentsch, T.J.
Science 344 (6184): 634-638. 9 May 2014

In silico screening for pathogenesis related-2 gene candidates in Vigna uguiculata transcriptome.
Wanderley-Nogueira, A.C. and Da Mota Soares-Cavalcanti, N. and Belarmino, L.C. and Barbosa-Silva, A. and Kido, E.A. and Do Monte, S.J.H. and Pandolfi, V. and Calsa-Junior, T. and Benko-Iseppon, A.M.
Lecture Notes in Computer Science 6160 : 70-81. 2010

uORFdb - a comprehensive literature database on eukaryotic uORF biology.
Wethmar, K. and Barbosa-Silva, A. and Andrade-Navarro, M.A. and Leutz, A.
Nucleic Acids Research 42 (1): D60-D67. 1 January 2014

Comprehensive translational control of tyrosine kinase expression by upstream open reading frames.
Wethmar, K. and Schulz, J. and Muro, E.M. and Talyan, S. and Andrade-Navarro, M.A. and Leutz, A.
Oncogene 35 (13): 1736-1742. 31 March 2016

Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery.
Zhang, G. and Hoersch, S. and Amsterdam, A. and Whittaker, C.A. and Beert, E. and Catchen, J.M. and Farrington, S. and Postlethwait, J.H. and Legius, E. and Hopkins, N. and Lees, J.A.
PLoS Genetics 9 (8): e1003734. August 2013

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.
Zhang, G. and Hoersch, S. and Amsterdam, A. and Whittaker, C.A. and Lees, J.A. and Hopkins, N.
Proceedings of the National Academy of Sciences of the United States of America 107 (39): 16940-16945. 28 September 2010

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P. and Kaergel, E. and Heinig, M. and Fontaine, J.F. and Patone, G. and Muro, E.M. and Mathas, S. and Hummel, M. and Andrade-Navarro, M.A. and Hübner, N. and Scheidereit, C.
Genome Medicine 8 (1): 28. 17 March 2016

SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations.
von Eichborn, J. and Dunkel, M. and Gohlke, B.O. and Preissner, S.C. and Hoffmann, M.F. and Bauer, J.M.J. and Armstrong, J.D. and Schaefer, M.H. and Andrade-Navarro, M.A. and Le Novere, N. and Croning, M.D.R. and Grant, S.G.N. and van Nierop, P. and Smit, A.B. and Preissner, R.
Nucleic Acids Research 41 (D1): D834-D840. 1 January 2013

Bader, Michael

Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L. and Peeva, P. and Ramos-Prats, A. and Alenina, N. and Winter, Y. and Rivalan, M.
Behavioural Brain Research 29 August 2019 (In Press)

Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D. and Luft, F.C. and Bader, M. and Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90 (5): 495-508. May 2012

Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A. and Kny, M. and Pablo-Tortola, C. and Todiras, M. and Willenbrock, M. and Schmidt, S. and Schmoeckel, K. and Jorde, I. and Nowak, M. and Jarosch, E. and Sommer, T. and Bröker, B.M. and Felix, S.B. and Scheidereit, C. and Weber-Carstens, S. and Butter, C. and Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 23 August 2019 (In Press)

Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G. and Uhlemann, R. and Richter, N. and Klempin, F. and Wegner, S. and Staerck, L. and Wolf, S. and Uckert, W. and Kettenmann, H. and Endres, M. and Gertz, K.
Acta Neuropathologica 135 (4): 551. April 2018

CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A. and Qadri, F. and Leukel, L. and Yilmaz, R. and Fontaine, J.F. and Sihn, G. and Bader, M. and Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123 (3): 1343-1347. 1 March 2013

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.
Werth, M. and Walentin, K. and Aue, A. and Schoenheit, J. and Wuebken, A. and Pode-Shakked, N. and Vilianovitch, L. and Erdmann, B. and Dekel, B. and Bader, M. and Barasch, J. and Rosenbauer, F. and Luft, F.C. and Schmidt-Ott, K.M.
Development 137 (22): 3835-3845. November 2010

Bargou, Ralf C.

CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations.
Arce, S. and Luger, E. and Muehlinghaus, G. and Cassese, G. and Hauser, A. and Horst, A. and Lehnert, K. and Odendahl, M. and Hoenemann, D. and Heller, K.D. and Kleinschmidt, H. and Berek, C. and Doerner, T. and Krenn, V. and Hiepe, F. and Bargou, R. and Radbruch, A. and Manz, R.A.
Journal of Leukocyte Biology 75 : 1022-1028. 1 January 2004

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M. and Stuehmer, T. and Herrmann, P. and Bommert, K. and Doerken, B. and Bargou, R.C.
Blood 104 (12): 3712-3721. 1 January 2004

T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3-bispecific single-chain antibody construct1.
Dreier, T. and Baeuerle, P.A. and Fichtner, I. and Gruen, M. and Schlereth, B. and Lorenczewski, G. and Kufer, P. and Lutterbuese, R. and Riethmueller, G. and Gjorstrup, P. and Bargou, R.C.
Journal of Immunology 170 (8): 4397-4402. 15 April 2003

T-cell-mediated lysis of B cells induced by a CD19xCD3 bispecific single-chain antibody is perforin dependent and death receptor independent.
Gruen, M. and Bommert, K. and Bargou, R.C.
Cancer Immunology Immunotherapy 53 (7): 625-632. 1 January 2004

A novel recombinant bispecific single-chain antibody, bscWue-1 x CD3, induces T-cell-mediated cytotoxicity towards human multiple myeloma cells.
Hoenemann, D. and Kufer, P. and Rimpler, M.M. and Chatterjee, M. and Friedl, S. and Riecher, F. and Bommert, K. and Doerken, B. and Bargou, R.C.
Leukemia 18 (3): 636-644. 1 January 2004

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F. and Schulze-Proebsting, K. and Anagnostopoulos, I. and Muehlinghaus, G. and Chatterjee, M. and Mathas, S. and Bargou, R.C. and Manz, R. and Stein, H. and Doerken, B.
Blood 103 (9): 3511-3515. 1 January 2004

PI3-K/AKT/FKHR and MAPK signaling cascades are redundantly stimulated by a variety of cytokines and contribute independently to proliferation and survival of multiple myeloma cells.
Lentzsch, S. and Chatterjee, M. and Gries, M. and Bommert, K. and Gollasch, H. and Doerken, B. and Bargou, R.C.
Leukemia 18 (11): 1883-1890. 1 January 2004

Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S. and Gries, M. and Janz, M. and Bargou, R. and Doerken, B. and Mapara, M.Y.
Blood 101 (9): 3568-3573. 1 May 2003

Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19/anti-CD3 single-chain antibody construct.
Loeffler, A. and Gruen, M. and Wuchter, C. and Schriever, F. and Kufer, P. and Dreier, T. and Hanakam, F. and Baeuerle, P.A. and Bommert, K. and Karawajew, L. and Doerken, B. and Bargou, R.C.
Leukemia 17 (5): 900-909. May 2003

Behlke, Joachim

Oligomeric structure of mammalian purine nucleoside phosphorylase in solution determined by analytical ultracentrifugation.
Behlke, J. and Koellner, G. and Bzowska, A.
Zeitschrift fuer Naturforschung C, A Journal of Biosciences 60 (11-12): 927-931. November 2005

Protein crystallization with and without precipitants.
Behlke, J. and Marg, A. and Paeschke, M.
Journal of Applied Crystallography 30 (5/1): 559-560. 1 October 1997

Enhanced resolution of sedimentation coefficient distribution profiles by extrapolation to infinite time.
Behlke, J. and Ristau, O.
European Biophysics Journal 39 (3): 449-455. February 2010

Molecular mass determination by sedimentation velocity experiments and direct fitting of the concentration profiles.
Behlke, J. and Ristau, O.
Biophysical Journal 72 (1): 428-434. January 1997

Self-association of adrenodoxin studied by using analytical ultracentrifugation.
Behlke, J. and Ristau, O. and Mueller, E.C. and Hannemann, F. and Bernhardt, R.
Biophysical Chemistry 125 (1): 159-165. January 2007

In vitro and in vivo stability of the epsilon2zeta2 protein complex of the broad host-range Streptococcus pyogenes pSM19035 addiction system.
Camacho, A.G. and Misselwitz, R. and Behlke, J. and Ayora, S. and Welfle, K. and Meinhart, A. and Lara, B. and Saenger, W. and Welfle, H. and Alonso, J.C.
Biological Chemistry 383 (11): 1701-1713. November 2002

X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
Manjasetty, B.A. and Niesen, F.H. and Scheich, C. and Roske, Y. and Goetz, F. and Behlke, J. and Sievert, V. and Heinemann, U. and Buessow, K.
BMC Structural Biology 5 (14): 21. 14 December 2005

Crystal structures of human saposins C and D: implications for lipid recognition and membrane interactions.
Rossmann, M. and Schultz-Heienbrok, R. and Behlke, J. and Remmel, N. and Alings, C. and Sandhoff, K. and Saenger, W. and Maier, T.
Structure 16 (5): 809-817. 7 May 2008

Structural and functional characterization of human Iba proteins.
Schulze, J.O. and Quedenau, C. and Roske, Y. and Adam, T. and Schueler, H. and Behlke, J. and Turnbull, A.P. and Sievert, V. and Scheich, C. and Mueller, U. and Heinemann, U. and Buessow, K.
FEBS Journal 275 (18): 4627-4640. September 2008

CopR binds and bends its target DNA: a footprinting and fluorescence resonance energy transfer study.
Steinmetzer, K. and Behlke, J. and Brantl, S. and Lorenz, M.
Nucleic Acids Research 30 (9): 2052-2060. 1 May 2002

Beitraege zur Struktur und Funktion des kleinen Saeuger-Stressproteins HSP25 unter besonderer Beruecksichtigung der Wechselwirkung mit Actin.
Wieske, M.
UNSPECIFIED thesis, UNSPECIFIED. 22 September 1998

Bergmann, Martin W.

Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A. and Zelarayan, L. and Betney, R. and Gehrke, C. and Dunger, S. and Noack, C. and Busjahn, A. and Huelsken, J. and Taketo, M.M. and Birchmeier, W. and Dietz, R. and Bergmann, M.W.
Circulation Research 100 (9): 1353-1362. 11 May 2007

Besser, Daniel

Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.
Besser, D. and Bardelli, A. and Didichenko, S. and Thelen, M. and Comoglio, P.M. and Ponzetto, C. and Nagamine, Y.
Oncogene 14 (6): 705-711. 13 February 1997

A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.
Besser, D. and Bromberg, J.F. and Darnell, J.E. and Hanafusa, H.
Molecular and Cellular Biology 19 (2): 1401-1409. February 1999

DNA methylation inhibits transcription by RNA polymerase III of a tRNA gene, but not of a 5S rRNA gene.
Besser, D. and Goetz, F. and Schulze-Forster, K. and Wagner, H. and Kroeger, H. and Simon, D.
FEBS Letters 269 (2): 358-362. 3 September 1990

Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts.
Besser, D. and Presta, M. and Nagamine, Y.
Cell Growth & Differentiation 6 (8): 1009-1017. August 1995

Urokinase-type plasminogen activator gene regulation by polyomavirus middle-T antigen.
Besser, D. and Urich, M. and Sakaue, M. and Messerschmitt, A. and Ballmer-Hofer, K. and Nagamine, Y.
Oncogene 11 (11): 2383-2391. 7 December 1995

Signal transduction and the u-PA/u-PAR system.
Besser, D. and Verde, P. and Nagamine, Y. and Blasi, F.
Fibrinolysis 10 (4): 215-237. July 1996

Stem cell biology-from basic research to regenerative medicine.
Besser, D.
Journal of Molecular Medicine 90 (7): 731-733. July 2012

Expression of nodal, lefty-A, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.
Besser, D.
Journal of Biological Chemistry 279 (43): 45076-45084. 1 January 2004

Replicative aging and differentiation potential of human adipose tissue-derived mesenchymal stromal cells expanded in pooled human or fetal bovine serum.
Bieback, K. and Hecker, A. and Schlechter, T. and Hofmann, I. and Brousos, N. and Redmer, T. and Besser, D. and Klueter, H. and Mueller, A.M. and Becker, M.
Cytotherapy 14 (5): 570-583. May 2012

Mesenchymal stromal cells (MSCs): science and f(r)iction.
Bieback, K. and Wuchter, P. and Besser, D. and Franke, W. and Becker, M. and Ott, M. and Pacher, M. and Ma, N. and Stamm, C. and Klueter, H. and Mueller, A. and Ho, A.D.
Journal of Molecular Medicine 90 (7): 773-782. July 2012

SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction.
Birge, R.B. and Knudsen, B.S. and Besser, D. and Hanafusa, H.
Genes to Cells 1 (7): 595-613. July 1996

Stat3 activation is required for cellular transformation by v-src.
Bromberg, J.F. and Horvath, C.M. and Besser, D. and Lathem, W.W. and Darnell, J.E.
Molecular and Cellular Biology 18 (5): 2553-2558. May 1998

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R. and Sternjak, A. and Wend, P. and Momma, S. and Campos, B. and Herrmann, I.M. and Graf, D. and Mitsiadis, T. and Herold-Mende, C. and Besser, D. and Synowitz, M. and Kettenmann, H. and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2.
D'Orazio, D. and Besser, D. and Marksitzer, R. and Kunz, C. and Hume, D.A. and Kiefer, B. and Nagamine, Y.
Gene 201 (1-2): 179-187. 12 November 1997

FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells.
Diecke, S. and Quiroga-Negreira, A. and Redmer, T. and Besser, D.
Cells Tissues Organs 188 (1-2): 52-61. July 2008

12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells.
El-Shemerly, M.Y. and Besser, D. and Nagasawa, M. and Nagamine, Y.
Journal of Biological Chemistry 272 (49): 30599-30602. 5 December 1997

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J. and Morkel, M. and Besser, D. and Budczies, J. and Kosel, F. and Brembeck, F.H. and Stein, U. and Fichtner, I. and Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V. and Durrieu-Gaillard, S. and Dumay-Odelot, H. and Da Silva, D. and Rey, C. and Prochazkova, M. and Roeder, R.G. and Besser, D. and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107 (9): 4176-4181. 2 March 2010

Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway.
Irigoyen, J.P. and Besser, D. and Nagamine, Y.
Journal of Biological Chemistry 272 (3): 1904-1909. 17 January 1997

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells.
James, D. and Levine, A.J. and Besser, D. and Hemmati-Brivanlou, A.
Development 132 (6): 1273-1282. March 2005

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.
Kaufman, W.L. and Kocman, I. and Agrawal, V. and Rahn, H.P. and Besser, D. and Gossen, M.
Nucleic Acids Research 36 (17): e111. October 2008

Transcriptional regulation of the murine urokinase-type plasminogen activator gene in skeletal myoblasts.
Miralles, F. and Ibanez-Tallon, I. and Parra, M. and Crippa, M. and Blasi, F. and Besser, D. and Nagamine, Y. and Munoz-Canoves, P.
Thrombosis and Haemostasis 81 (5): 767-774. May 1999

E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
Redmer, T. and Diecke, S. and Grigoryan, T. and Quiroga-Negreira, A. and Birchmeier, W. and Besser, D.
EMBO Reports 12 (7): 720-726. 1 July 2011

Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M. and Besser, D. and Benitah, S.A.
EMBO Reports 13 (1): 9-11. January 2012

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Su, F. and Overholtzer, M. and Besser, D. and Levine, A.J.
Genes & Development 16 (1): 46-57. 2002

Activation and nuclear translocation of mitogen-activated protein kinases by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase.
Urich, M. and el Shemerly, M.Y. and Besser, D. and Nagamine, Y. and Ballmer-Hofer, K.
Journal of Biological Chemistry 270 (49): 29286-29292. 8 December 1995

Protein kinase B beta/Akt2 plays a specific role in muscle differentiation.
Vandromme, M. and Rochat, A. and Meier, R. and Carnac, G. and Besser, D. and Hemmings, B.A. and Fernandez, A. and Lamb, N.J.
Journal of Biological Chemistry 276 (11): 8173-8179. 16 March 2001

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. and Xie, G. and Singh, M. and Ghanbarian, A.T. and Raskó, T. and Szvetnik, A. and Cai, H. and Besser, D. and Prigione, A. and Fuchs, N.V. and Schumann, G.G. and Chen, W. and Lorincz, M.C. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.
Wolfrum, C. and Besser, D. and Luca, E. and Stoffel, M.
Proceedings of the National Academy of Sciences of the United States of America 100 (20): 11624-11629. 30 September 2003

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src.
Wong, B.R. and Besser, D. and Kim, N. and Arron, J.R. and Vologodskaia, M. and Hanafusa, H. and Choi, Y.
Molecular Cell 4 (6): 1041-1049. December 1999

Independent and cooperative activation of chromosomal c-fos promoter by STAT3.
Yang, E. and Lerner, L. and Besser, D. and Darnell, J.E.
Journal of Biological Chemistry 278 (18): 15794-15799. 2 May 2003

Beule, Dieter (MDC/BIH)

The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A. and Babila, J.T. and Wiglenda, T. and Diez, L. and Jacob, M. and Nietfeld, W. and Huska, M.R. and Haenig, C. and Groenke, N. and Buntru, A. and Blanc, E. and Meier, J.C. and Vannoni, E. and Erck, C. and Friedrich, B. and Martens, H. and Neuendorf, N. and Schnoegl, S. and Wolfer, D.P. and Loos, M. and Beule, D. and Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26 (1): 109-120. 17 January 2019

WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N. and Gloaguen, Y. and Opialla, T. and Blanc, E. and Sicard, E. and Royer, A.L. and Le Bizec, B. and Durand, S. and Migné, C. and Pétéra, M. and Pujos-Guillot, E. and Giacomoni, F. and Guitton, Y. and Beule, D. and Kirwan, J.
Metabolites 9 (9): 171. 21 August 2019

WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N. and Gloaguen, Y. and Opialla, T. and Blanc, E. and Sicard, E. and Royer, A.L. and Le Bizec, B. and Durand, S. and Migné, C. and Pétéra, M. and Pujos-Guillot, E. and Giacomoni, F. and Guitton, Y. and Beule, D. and Kirwan, J.
bioRxiv : 713925. 24 July 2019

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. and Friese, C. and Arina, A. and Idel, C. and Briesemeister, D. and Rothe, M. and Ivanov, A. and Szymborska, A. and Patone, G. and Kunz, S. and Sommermeyer, D. and Engels, B. and Leisegang, M. and Textor, A. and Fehling, H.J. and Fruttiger, M. and Lohoff, M. and Herrmann, A. and Yu, H. and Weichselbaum, R. and Uckert, W. and Hübner, N. and Gerhardt, H. and Beule, D. and Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

SigsPack, a package for cancer mutational signatures.
Schumann, F. and Blanc, E. and Messerschmidt, C. and Blankenstein, T. and Busse, A. and Beule, D.
BMC Bioinformatics 20 (1): 450. 2 September 2019

Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole, T.M. and Toedling, J. and Sprüssel, A. and Pfeil, S. and Savelyeva, L. and Capper, D. and Messerschmidt, C. and Beule, D. and Groeneveld-Krentz, S. and Eckert, C. and Gambara, G. and Henssen, A.G. and Finkler, S. and Schulte, J.H. and Sieber, A. and Bluethgen, N. and Regenbrecht, C.R.A. and Künkele, A. and Lodrini, M. and Eggert, A. and Deubzer, H.E.
International Journal of Cancer 15 July 2019 (In Press)

Bielka, Heinz

Arnold Graffi (1910-2006) : A pioneer of experimental cancer research.
Wunderlich, V. and Bielka, H.
Journal of Cancer Research and Clinical Oncology 132 (8): 483-485. August 2006

Bimmler, Marion

Antibodies to the alpha(1)-adrenergic receptor cause vascular impairments in rat brain as demonstrated by magnetic resonance angiography.
Karczewski, P. and Pohlmann, A. and Wagenhaus, B. and Wisbrun, N. and Hempel, P. and Lemke, B. and Kunze, R. and Niendorf, T. and Bimmler, M.
PLoS ONE 7 (7): e41602. 30 July 2012

Birchmeier, Walter

Gab1 and Mapk signaling are essential in the hair cycle and hair follicle stem cell quiescence.
Akilli Öztürk, Ö. and Pakula, H. and Chmielowiec, J. and Qi, J. and Stein, S. and Lan, L. and Sasaki, Y. and Rajewsky, K. and Birchmeier, W.
Cell Reports 13 (3): 561-572. 20 October 2015

Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.
Augustin, I. and Gross, J. and Baumann, D. and Korn, C. and Kerr, G. and Grigoryan, T. and Mauch, C. and Birchmeier, W. and Boutros, M.
Journal of Experimental Medicine 210 (9): 1761-1777. 26 August 2013

Role of β-catenin in synaptic vesicle localization and presynaptic assembly.
Bamji, S.X. and Shimazu, K. and Kimes, N. and Huelsken, J. and Birchmeier, W. and Lu, B. and Reichardt, L.F.
Neuron 40 (4): 719-731. November 2003

Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A. and Zelarayan, L. and Betney, R. and Gehrke, C. and Dunger, S. and Noack, C. and Busjahn, A. and Huelsken, J. and Taketo, M.M. and Birchmeier, W. and Dietz, R. and Bergmann, M.W.
Circulation Research 100 (9): 1353-1362. 11 May 2007

Control of beta-catenin signaling in tumor development.
Behrens, J.
Annals of the New York Academy of Sciences 910 : 21-35. June 2000

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Behrens, J. and Jerchow, B.A. and Wuertele, M. and Grimm, J. and Asbrand, C. and Wirtz, R. and Kuehl, M. and Wedlich, D. and Birchmeier, W.
Science 280 (5363): 596-599. 24 April 1998

Functional interaction of beta-catenin with the transcription factor LEF-1.
Behrens, J. and von Kries, J.P. and Kuehl, M. and Bruhn, L. and Wedlich, D. and Grosschedl, R. and Birchmeier, W.
Nature 382 (6592): 638-642. 15 August 1996

Expression of nodal, lefty-A, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3.
Besser, D.
Journal of Biological Chemistry 279 (43): 45076-45084. 1 January 2004

Hormonal induction of functional differentiation and mammary-derived growth inhibitor expression in cultured mouse mammary gland explants.
Binas, B. and Spitzer, E. and Zschiesche, W. and Erdmann, B. and Kurtz, A. and Mueller, T. and Niemann, C. and Blenau, W. and Grosse, R.
In Vitro Cellular & Developmental Biology 28A (9-10): 625-634. September 1992

Molecular aspects of mesenchymal-epithelial interactions.
Birchmeier, C. and Birchmeier, W.
Annual Review of Cell Biology 9 : 511-540. 1993

Met, metastasis, motility and more.
Birchmeier, C. and Birchmeier, W. and Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003

Orchestrating Wnt signalling for metabolic liver zonation.
Birchmeier, W.
Nature Cell Biology 18 (5): 463-465. May 2016

Stem cells: Orphan receptors find a home.
Birchmeier, W.
Nature 476 (7360): 287-288. 18 August 2011

Cell adhesion and signal transduction in cancer.
Birchmeier, W.
EMBO Reports 6 (5): 413-417. 1 January 2005

Mittel zur Beeinflussung der Zelldifferenzierung und seine Verwendung.
Birchmeier, W.
DE19509792A1. 19 September 1996

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness.
Birchmeier, W. and Behrens, J.
Biochimica et Biophysica Acta 1198 (1): 11-26. 27 May 1994

The role of Irf6 in tooth epithelial invagination.
Blackburn, J. and Ohazama, A. and Kawasaki, K. and Otsuka-Tanaka, Y. and Liu, B. and Honda, K. and Rountree, R.B. and Hu, Y. and Kawasaki, M. and Birchmeier, W. and Schmidt-Ullrich, R. and Kinoshita, A. and Schutte, B.C. and Hammond, N.L. and Dixon, M.J. and Sharpe, P.T.
Developmental Biology 365 (1): 61-70. 1 May 2012

Balancing cell adhesion and Wnt signaling, the key role of beta-catenin.
Brembeck, F.H. and Rosario, M. and Birchmeier, W.
Current Opinion in Genetics & Development 16 (1): 51-59. February 2006

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Brembeck, F.H. and Schwarz-Romond, T. and Bakkers, J. and Wilhelm, S. and Hammerschmidt, M. and Birchmeier, W.
Genes & Development 18 (18): 2225-2230. 15 September 2004

BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H. and Wiese, M. and Zatula, N. and Grigoryan, T. and Dai, Y. and Fritzmann, J. and Birchmeier, W.
Gastroenterology 141 (4): 1359-1370. October 2011

Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.
Brinkmann, V. and Foroutan, H. and Sachs, M. and Weidner, K.M. and Birchmeier, W.
Journal of Cell Biology 131 (6 Pt. 1): 1573-1586. December 1995

Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas.
Busch, J. and Ralla, B. and Jung, M. and Wotschofsky, Z. and Trujillo-Arribas, E. and Schwabe, P. and Kilic, E. and Fendler, A. and Jung, K.
Journal of Experimental & Clinical Cancer Research 34 (1): 61. 14 June 2015

Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.
Cerrone, M. and Noorman, M. and Lin, X. and Chkourko, H. and Liang, F.X. and van der Nagel, R. and Hund, T. and Birchmeier, W. and Mohler, P. and van Veen, T.A. and van Rijen, H.V. and Delmar, M.
Cardiovascular Research 95 (4): 460-468. 1 September 2012

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R. and Sternjak, A. and Wend, P. and Momma, S. and Campos, B. and Herrmann, I.M. and Graf, D. and Mitsiadis, T. and Herold-Mende, C. and Besser, D. and Synowitz, M. and Kettenmann, H. and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

c-Met is essential for wound healing in the skin.
Chmielowiec, J. and Borowiak, M. and Morkel, M. and Stradal, T. and Munz, B. and Werner, S. and Wehland, J. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response.
Churin, Y. and Al Ghoul, L. and Kepp, O. and Meyer, T.E. and Birchmeier, W. and Naumann, M.
Journal of Cell Biology 161 (2): 249-255. 28 April 2003

The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3β interaction protein (GSKIP) regulates β-catenin through its interactions with both protein kinase A (PKA) and GSK3β.
Dema, A. and Schröter, M.F. and Perets, E. and Skroblin, P. and Moutty, M.C. and Deàk, V.A. and Birchmeier, W. and Klussmann, E.
Journal of Biological Chemistry 291 (37): 19618-19630. 9 September 2016

FGF2 signaling in mouse embryonic fibroblasts is crucial for self-renewal of embryonic stem cells.
Diecke, S. and Quiroga-Negreira, A. and Redmer, T. and Besser, D.
Cells Tissues Organs 188 (1-2): 52-61. July 2008

From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic acid and db-cAMP in vitro differentiation model.
Drab, M. and Haller, H. and Bychkov, R. and Erdmann, B. and Lindschau, C. and Haase, H. and Morano, I. and Luft, F.C. and Wobus, A.M.
FASEB Journal 11 (11): 905-915. September 1997

A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis.
Fang, L. and Zhu, Q. and Neuenschwander, M. and Specker, E. and Wulf-Goldenberg, A. and Weis, W.I. and von Kries, J.P. and Birchmeier, W.
Cancer Research 76 (4): 891-901. 15 February 2016

Beta-catenin regulates P-cadherin expression in mammary basal epithelial cells.
Faraldo, M.M. and Teuliere, J. and Deugnier, M.A. and Birchmeier, W. and Huelsken, J. and Thiery, J.P. and Cano, A. and Glukhova, M.A.
FEBS Letters 581 (5): 831-836. 6 March 2007

The translational potential of microRNAs as biofluid markers of urological tumours.
Fendler, A. and Stephan, C. and Yousef, G.M. and Kristiansen, G. and Jung, K.
Nature Reviews Urology 13 (12): 734-752. December 2016

Keratinocyte-specific ablation of protease-activated receptor-2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease.
Francis, N. and Ayodele, B.A. and O'Brien-Simpson, N.M. and Birchmeier, W. and Pike, R.N. and Pagel, C.N. and Mackie, E.J.
Cellular Microbiology 20 (11): e12891. November 2018

Circular RNAs: a new class of biomarkers as a rising interest in laboratory medicine.
Franz, A. and Rabien, A. and Stephan, C. and Ralla, B. and Fuchs, S. and Jung, K. and Fendler, A.
Clinical Chemistry and Laboratory Medicine 56 (12): 1992-2003. December 2018

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J. and Morkel, M. and Besser, D. and Budczies, J. and Kosel, F. and Brembeck, F.H. and Stein, U. and Fichtner, I. and Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B. and Heuser, A. and Wichter, T. and Paul, M. and Basson, C.T. and McDermott, D.A. and Lerman, B.B. and Markowitz, S.M. and Ellinor, P.T. and MacRae, C.A. and Peters, S. and Grossmann, K.S. and Drenckhahn, J. and Michely, B. and Sasse-Klaassen, S. and Birchmeier, W. and Dietz, R. and Breithardt, G. and Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36 (11): 1162-1164. November 2004

Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: Implications for cell adhesion and signaling.
Ghadimi, B.M. and Behrens, J. and Hoffmann, I. and Haensch, W. and Birchmeier, W. and Schlag, P.M.
European Journal of Cancer 35 (1): 60-65. January 1999

Targeting MET in cancer: rationale and progress.
Gherardi, E. and Birchmeier, W. and Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

Molecular signaling mechanisms of axon-glia communication in the peripheral nervous system.
Grigoryan, T. and Birchmeier, W.
BioEssays 37 (5): 502-513. May 2015

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T. and Stein, S. and Qi, J. and Wende, H. and Garratt, A.N. and Nave, K.A. and Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
Grigoryan, T. and Wend, P. and Klaus, A. and Birchmeier, W.
Genes & Development 22 (17): 2308-2341. 1 September 2008

Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
Grimm, J. and Sachs, M. and Britsch, S. and Di Cesare, S. and Schwarz-Romond, T. and Birchmeier, W.
Journal of Cell Biology 154 (2): 345-354. 23 July 2001

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S. and Eckert, C. and Arkona, C. and Radetzki, S. and Böhm, K. and Heinemann, U. and Wolber, G. and von Kries, J.P. and Birchmeier, W. and Rademann, J.
ChemMedChem 10 (5): 815-826. May 2015

Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
Grossmann, K.S. and Grund, C. and Huelsken, J. and Behrend, M. and Erdmann, B. and Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 167 (1): 149-160. 11 October 2004

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S. and Rosario, M. and Birchmeier, C. and Birchmeier, W.
Advances in Cancer Research 106 : 53-89. 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Functional involvement of CD44, a family of cell adhesion molecules, in immune responses, tumour progression and haematopoiesis.
Guenthert, U. and Schwaerzler, C. and Wittig, B. and Laman, J. and Ruiz, P. and Stauder, R. and Bloem, A. and Smadja-Joffe, F. and Zoeller, M. and Rolink, A.
Advances in Experimental Medicine and Biology 451 : 43-49. 1998

Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Hadjihannas, M.V. and Brueckner, M. and Jerchow, B. and Birchmeier, W. and Dietmaier, W. and Behrens, J.
Proceedings of the National Academy of Sciences of the United States of America 103 (28): 10747-10752. 11 July 2006

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V. and Durrieu-Gaillard, S. and Dumay-Odelot, H. and Da Silva, D. and Rey, C. and Prochazkova, M. and Roeder, R.G. and Besser, D. and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107 (9): 4176-4181. 2 March 2010

Shp-2 inhibitors, pharmaceutical compositions comprising them and their use for treating phosphatase-mediated diseases [Shp-2-Inhibitoren, Arzneimittel, die sie enthalten sowie deren Verwendung zur Behandlung von Phosphatasen-vermittelten Krankheiten].
Hellmuth, K. and Birchmeier, W.
EP1728790 ; WO06128909. 6 December 2006

Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
Hellmuth, K. and Grosskopf, S. and Lum, C.T. and Wuertele, M. and Roeder, N. and von Kries, J.P. and Rosario, M. and Rademann, J. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 105 (20): 7275-7280. 20 May 2008

Interplay of cadherin-mediated cell adhesion and canonical wnt signaling.
Heuberger, J. and Birchmeier, W.
Cold Spring Harbor Perspectives in Biology 2 (2): a002915. February 2010

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J. and Kosel, F. and Qi, J. and Grossmann, K.S. and Rajewsky, K. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 111 (9): 3472-3477. 4 March 2014

A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis.
Heuberger, J. and Hill, U. and Förster, S. and Zimmermann, K. and Malchin, V. and Kühl, A.A. and Stein, U. and Vieth, M. and Birchmeier, W. and Leutz, A.
Life Science Alliance 2 (1): e201800173. February 2019

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.
Hill, T.P. and Spaeter, D. and Taketo, M.M. and Birchmeier, W. and Hartmann, C.
Developmental Cell 8 (5): 727-738. 1 May 2005

Multiple roles of mesenchymal beta-catenin during murine limb patterning.
Hill, T.P. and Taketo, M.M. and Birchmeier, W. and Hartmann, C.
Development 133 (7): 1219-1229. 1 April 2006

Expression of multidrug resistance proteins (Mrps) in astrocytes of the mouse brain: a single cell rt-PCR study.
Hirrlinger, J. and Moeller, H. and Kirchhoff, F. and Dringen, R.
Neurochemical Research 30 (10): 1237-1244. 1 October 2005

Rap1 regulates the formation of E-cadherin-based cell-cell contacts.
Hogan, C. and Serpente, N. and Cogram, P. and Hosking, C.R. and Bialucha, C.U. and Feller, S.M. and Braga, V.M.M. and Birchmeier, W. and Fujita, Y.
Molecular and Cellular Biology 24 (15): 6690-6700. 1 January 2004

Wnt signaling in stem and cancer stem cells.
Holland, J.D. and Klaus, A. and Garratt, A.N. and Birchmeier, W.
Current Opinion in Cell Biology 25 (2): 254-264. April 2013

Combined Wnt/β-catenin, met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome.
Holland, J.D. and Györffy, B. and Vogel, R. and Eckert, K. and Valenti, G. and Fang, L. and Lohneis, P. and Elezkurtaj, S. and Ziebold, U. and Birchmeier, W.
Cell Reports 5 (5): 1214-1227. 12 December 2013

The transcriptional repressor Glis2 is a novel binding partner for p120 catenin.
Hosking, C.R. and Ulloa, F. and Hogan, C. and Ferber, E. and Figueroa, A. and Gevaert, K. and Birchmeier, W. and Briscoe, J. and Fujita, Y.
Molecular Biology of the Cell 18 (5): 1918-1927. 1 May 2007

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
Huelsken, J. and Birchmeier, W. and Behrens, J.
Journal of Cell Biology 127 (6 Pt. 2): 2061-2069. December 1994

Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J. and Vogel, R. and Brinkmann, V. and Erdmann, B. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 148 (3): 567-578. 7 February 2000

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
Huelsken, J. and Vogel, R. and Erdmann, B. and Cotsarelis, G. and Birchmeier, W.
Cell 105 (4): 533-545. 18 May 2001

Plakoglobin is essential for myocardial compliance but dispensable for myofibril insertion into adherens junctions.
Isac, C.M. and Ruiz, P. and Pfitzmaier, B. and Haase, H. and Birchmeier, W. and Morano, I.
Journal of Cellular Biochemistry 72 (1): 8-15. 1 January 1999

Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling.
Jaervinen, E. and Salazar-Ciudad, I. and Birchmeier, W. and Taketo, M.M. and Jernvall, J. and Thesleff, I.
Proceedings of the National Academy of Sciences of the United States of America 103 (49): 18627-18632. 5 December 2006

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Jeannet, G. and Scheller, M. and Scarpellino, L. and Duboux, S. and Gardiol, N. and Back, J. and Kuttler, F. and Malanchi, I. and Birchmeier, W. and Leutz, A. and Huelsken, J. and Held, W.
Blood 111 (1): 142-149. 1 January 2008

Genetische Analyse von Conductin durch zielgerichtete Mutagenese in der Maus.
Jerchow, B.
UNSPECIFIED thesis, UNSPECIFIED. 6 May 2003

Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Juerchott, K. and Kuban, R.J. and Krech, T. and Bluethgen, N. and Stein, U. and Walther, W. and Friese, C. and Kielbasa, S.M. and Ungethuem, U. and Lund, P. and Knoesel, T. and Kemmner, W. and Morkel, M. and Fritzmann, J. and Schlag, P.M. and Birchmeier, W. and Krueger, T. and Sperling, S. and Sers, C. and Royer, H.D. and Herzel, H. and Schaefer, R.
PLoS Genetics 6 (12): e1001231. 2 December 2010

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation.
Kaufman, W.L. and Kocman, I. and Agrawal, V. and Rahn, H.P. and Besser, D. and Gossen, M.
Nucleic Acids Research 36 (17): e111. October 2008

Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
Keilhack, H. and Mueller, M. and Boehmer, S.A. and Frank, C. and Weidner, K.M. and Birchmeier, W. and Ligensa, T. and Berndt, A. and Kosmehl, H. and Gunther, B. and Mueller, T. and Birchmeier, C. and Boehmer, F.D.
Journal of Cell Biology 152 (2): 325-334. 22 January 2001

Developmental signaling in myocardial progenitor cells: A comprehensive view of Bmp- and Wnt/beta-catenin signaling.
Klaus, A. and Birchmeier, W.
Pediatric Cardiology 30 (5): 609-616. July 2009

Wnt signalling and its impact on development and cancer.
Klaus, A. and Birchmeier, W.
Nature Reviews Cancer 8 (5): 387-398. May 2008

Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Klaus, A. and Mueller, M. and Schulz, H. and Saga, Y. and Martin, J.F. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 109 (27): 10921-10926. 3 July 2012

Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.
Klaus, A. and Saga, Y. and Taketo, M.M. and Tzahor, E. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104 (47): 18531-18536. 20 November 2007

Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas.
Koch, A. and Hrychyk, A. and Hartmann, W. and Waha, A. and Mikeska, T. and Waha, A. and Schueller, U. and Soerensen, N. and Berthold, F. and Goodyer, C.G. and Wiestler, O.D. and Birchmeier, W. and Behrens, J. and Pietsch, T.
International Journal of Cancer 121 (2): 284-291. 15 July 2007

Mutations and elevated transcriptional activity of conductin (AXIN2) in hepatoblastomas.
Koch, A. and Weber, N. and Waha, A. and Hartmann, W. and Denkhaus, D. and Behrens, J. and Birchmeier, W. and von Schweinitz, D. and Pietsch, T.
Journal of Pathology 204 (5): 546-554. 1 January 2004

Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells.
Kuerbitz, C. and Heise, D. and Redmer, T. and Goumas, F. and Arlt, A. and Lemke, J. and Rimbach, G. and Kalthoff, H. and Trauzold, A.
Cancer Science 102 (4): 728-734. April 2011

The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway.
Lamothe, B. and Yamada, M. and Schaeper, U. and Birchmeier, W. and Lax, I. and Schlessinger, J.
Molecular and Cellular Biology 24 (13): 5657-5666. 1 January 2004

Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.
Lan, L. and Holland, J.D. and Qi, J. and Grosskopf, S. and Rademann, J. and Vogel, R. and Gyoerffy, B. and Wulf-Goldenberg, A. and Birchmeier, W.
EMBO Journal 34 (11): 1493-1508. 3 June 2015

MicroRNA signature helps distinguish early from late biochemical failure in prostate cancer.
Lichner, Z. and Fendler, A. and Saleh, C. and Nasser, A.N. and Boles, D. and Al-Haddad, S. and Kupchak, P. and Dharsee, M. and Nuin, P.S. and Evans, K.R. and Jung, K. and Stephan, C. and Fleshner, N.E. and Yousef, G.M.
Clinical Chemistry 59 (11): 1595-1603. November 2013

Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients.
Lu, H. and Busch, J. and Jung, M. and Rabenhorst, S. and Ralla, B. and Kilic, E. and Mergemeier, S. and Budach, N. and Fendler, A. and Jung, K.
Clinica Chimica Acta 452 : 109-119. 15 January 2016

Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism.
MacRae, C.A. and Birchmeier, W. and Thierfelder, L.
Journal of Clinical Investigation 116 (7): 1825-1828. July 2006

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
Malanchi, I. and Peinado, H. and Kassen, D. and Hussenet, T. and Metzger, D. and Chambon, P. and Huber, M. and Hohl, D. and Cano, A. and Birchmeier, W. and Huelsken, J.
Nature 452 (7187): 650-653. 3 April 2008

Diversin regulates heart formation and gastrulation movements in development.
Moeller, H. and Jenny, A. and Schaeffer, H.J. and Schwarz-Romond, T. and Mlodzik, M. and Hammerschmidt, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 103 (43): 15900-15905. 24 October 2006

Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway.
Momeny, M. and Ghasemi, R. and Valenti, G. and Miranda, M. and Zekri, A. and Zarrinrad, G. and Javadikooshesh, S. and Yaghmaie, M. and Alimoghaddam, K. and Ghavamzadeh, A. and Ghaffari, S.H.
Tumor Biology 37 (3): 3913-3923. March 2016

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Momeny, M. and Saunus, J.M. and Marturana, F. and McCart Reed, A.E. and Black, D. and Sala, G. and Iacobelli, S. and Holland, J.D. and Yu, D. and Da Silva, L. and Simpson, P.T. and Khanna, K.K. and Chenevix-Trench, G. and Lakhani, S.R.
Oncotarget 6 (6): 3932-3946. 19 February 2015

β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.
Morkel, M. and Huelsken, J. and Wakamiya, M. and Ding, J. and van de Wetering, M. and Clevers, H. and Taketo, M.M. and Behringer, R.R. and Shen, M.M. and Birchmeier, W.
Development 130 (25): 6283-6294. 1 January 2003

β-catenin is required for specification of proximal/distal cell fate during lung morphogenesis.
Mucenski, M.L. and Wert, S.E. and Nation, J.M. and Loudy, D.E. and Huelsken, J. and Birchmeier, W. and Morrisey, E.E. and Whitsett, J.A.
Journal of Biological Chemistry 278 (41): 40231-40238. 10 October 2003

Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation.
Naerhi, K. and Jaervinen, E. and Birchmeier, W. and Taketo, M.M. and Mikkola, M.L. and Thesleff, I.
Development 135 (6): 1019-1028. March 2008

Reconstitution of mammary gland development in vitro: Requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.
Niemann, C. and Brinkmann, V. and Spitzer, E. and Hartmann, G. and Sachs, M. and Naundorf, H. and Birchmeier, W.
Journal of Cell Biology 143 (2): 533-545. 19 October 1998

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret, C. and Miah, S.M.S. and Rota, G. and Fonta, N.P. and Wang, H. and Held, W. and Birchmeier, W. and Sexl, V. and Yang, W. and Vivier, E. and Ho, P.C. and Brossay, L. and Guarda, G.
Nature Communications 10 (1): 1444. 29 March 2019

Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas.
Otto, T. and Birchmeier, W. and Schmidt, U. and Hinke, A. and Schipper, J. and Ruebben, H. and Raz, A.
Cancer Research 54 (12): 3120-3123. 15 June 1994

The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.
Pullikuth, A. and McKinnon, E. and Schaeffer, H.J. and Catling, A.D.
Molecular and Cellular Biology 25 (12): 5119-5133. 1 June 2005

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Qi, J. and Yu, Y. and Akilli Öztürk, Ö. and Holland, J.D. and Besser, D. and Fritzmann, J. and Wulf-Goldenberg, A. and Eckert, K. and Fichtner, I. and Birchmeier, W.
Gut 65 (10): 1690-1701. October 2016

KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells.
Qi, X.T. and Li, Y.L. and Zhang, Y.Q. and Xu, T. and Lu, B. and Fang, L. and Gao, J.Q. and Yu, L.S. and Zhu, D.F. and Yang, B. and He, Q.J. and Ying, M.D.
Acta Pharmacologica Sinica 40 (4): 546-555. April 2019

miR-9-5p in nephrectomy specimens is a potential predictor of primary resistance to first-line treatment with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma.
Ralla, B. and Busch, J. and Flörcken, A. and Westermann, J. and Zhao, Z. and Kilic, E. and Weickmann, S. and Jung, M. and Fendler, A. and Jung, K.
Cancers 10 (9): 321. 10 September 2018

E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
Redmer, T. and Diecke, S. and Grigoryan, T. and Quiroga-Negreira, A. and Birchmeier, W. and Besser, D.
EMBO Reports 12 (7): 720-726. 1 July 2011

Making tubes: Step by step.
Rosario, M. and Birchmeier, W.
Developmental Cell 7 (1): 3-5. 1 July 2004

How to make tubes: signaling by the Met receptor tyrosine kinase.
Rosario, M. and Birchmeier, W.
Trends in Cell Biology 13 (6): 328-335. June 2003

The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42.
Rosario, M. and Franke, R. and Bednarski, C. and Birchmeier, W.
Journal of Cell Biology 178 (3): 503-516. 30 July 2007

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.
Rosario, M. and Schuster, S. and Juettner, R. and Parthasarathy, S. and Tarabykin, V. and Birchmeier, W.
Genes & Development 26 (15): 1743-1757. 1 August 2012

Shp-2 is dispensable for establishing T cell exhaustion and for PD-1 signaling in vivo.
Rota, G. and Niogret, C. and Dang, A.T. and Barros, C.R. and Fonta, N.P. and Alfei, F. and Morgado, L. and Zehn, D. and Birchmeier, W. and Vivier, E. and Guarda, G.
Cell Reports 23 (1): 39-49. 3 April 2018

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Ruess, D.A. and Heynen, G.J. and Ciecielski, K.J. and Ai, J. and Berninger, A. and Kabacaoglu, D. and Görgülü, K. and Dantes, Z. and Wörmann, S.M. and Diakopoulos, K.N. and Karpathaki, A.F. and Kowalska, M. and Kaya-Aksoy, E. and Song, L. and Zeeuw van der Laan, E.A. and López-Alberca, M.P. and Nazaré, M. and Reichert, M. and Saur, D. and Erkan, M.M. and Hopt, U.T. and Sainz, B. and Birchmeier, W. and Schmid, R.M. and Lesina, M. and Algül, H.
Nature Medicine 24 (7): 954-960. July 2018

The plakoglobin knock-out mouse: A paradigm for the molecular analysis of cardiac cell junction formation.
Ruiz, P. and Birchmeier, W.
Trends in Cardiovascular Medicine 8 (3): 97-101. April 1998

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
Ruiz, P. and Brinkmann, V. and Ledermann, B. and Behrend, M. and Grund, C. and Thalhammer, C. and Vogel, F. and Birchmeier, C. and Guenthert, U. and Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 135 (1): 215-225. October 1996

Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Sachs, M. and Brohmann, H. and Zechner, D. and Mueller, T. and Huelsken, J. and Walther, I. and Schaeper, U. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 150 (6): 1375-1384. 18 September 2000

Motogenic and morphogenic activity of epithelial receptor tyrosine kinases.
Sachs, M. and Weidner, K.M. and Brinkmann, V. and Walther, I. and Obermeier, A. and Ullrich, A. and Birchmeier, W.
Journal of Cell Biology 133 (5): 1095-1107. 3 June 1996

HGF/SF c-Met signaling in the epithelial-mesenchymal transition and migration of muscle progenitor cells.
Schaeper, U. and Birchmeier, W.
In: Cell Migration in Development and Disease. Wiley-VCH, Weinheim, 191-204. ISBN 3-527-30587-4 1 January 2005

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
Schaeper, U. and Gehring, N.H. and Fuchs, K.P. and Sachs, M. and Kempkes, B. and Birchmeier, W.
Journal of Cell Biology 149 (7): 1419-1432. 26 June 2000

Tyrosine kinases.
Schaeper, U. and Grossmann, K.S.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1951-1959. ISBN 3-540-44244-8 2006

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Schaeper, U. and Vogel, R. and Chmielowiec, J. and Huelsken, J. and Rosario, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 104 (39): 15376-15381. 25 September 2007

Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
Scheller, M. and Huelsken, J. and Rosenbauer, F. and Taketo, M.M. and Birchmeier, W. and Tenen, D.G. and Leutz, A.
Nature Immunology 7 (10): 1037-1047. October 2006

The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
Schuetz, G. and Rosario, M. and Grimm, J. and Boeckers, T.M. and Gundelfinger, E.D. and Birchmeier, W.
Journal of Cell Biology 167 (5): 945-952. 6 December 2004

MEK Partner 1 (MP1): Regulation of oligomerization in MAP kinase signaling.
Sharma, C. and Vomastek, T. and Tarcsafalvi, A. and Catling, A.D. and Schaeffer, H.J. and Eblen, S.T. and Weber, M.J.
Journal of Cellular Biochemistry 94 (4): 708-719. 1 January 2005

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E. and McShane, E. and Cheret, C. and Walcher, J. and Müller, T. and Wulf-Goldenberg, A. and Hoelper, S. and Garratt, A.N. and Krüger, M. and Rajewsky, K. and Meijer, D. and Birchmeier, W. and Lewin, G.R. and Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung.
Shu, W. and Guttentag, S. and Wang, Z. and Andl, T. and Ballard, P. and Lu, M.M. and Piccolo, S. and Birchmeier, W. and Whitsett, J.A. and Millar, S.E. and Morrisey, E.E.
Developmental Biology 283 (1): 226-239. 1 January 2005

Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways.
Simonetti, M. and Agarwal, N. and Stösser, S. and Bali, K.K. and Karaulanov, E. and Kamble, R. and Pospisilova, B. and Kurejova, M. and Birchmeier, W. and Niehrs, C. and Heppenstall, P. and Kuner, R.
Neuron 83 (1): 104-121. 2 July 2014

Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: comparative analysis using six species of bathyergidae.
Smith, E.S.J. and Purfuerst, B. and Grigoryan, T. and Park, T.J. and Bennett, N.C. and Lewin, G.R.
Journal of Comparative Neurology 520 (12): 2785-2803. 15 August 2012

Limb development.
Soshnikova, N. and Birchmeier, W.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 1. Springer, Berlin [u.a.], 976-981. ISBN 3-540-44244-8 2006

Genetic interaction between Wnt/β-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Soshnikova, N. and Zechner, D. and Huelsken, J. and Mishina, Y. and Behringer, R.R. and Taketo, M.M. and Crenshaw, E.B. and Birchmeier, W.
Genes & Development 17 (16): 1963-1968. 1 January 2003

Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M. and Besser, D. and Benitah, S.A.
EMBO Reports 13 (1): 9-11. January 2012

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer.
Stein, U. and Arlt, F. and Walther, W. and Smith, J. and Waldman, T. and Harris, E.D. and Mertins, S.D. and Heizmann, C.W. and Allard, D. and Birchmeier, W. and Schlag, P.M. and Shoemaker, R.H.
Gastroenterology 131 (5): 1486-1500. November 2006

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Stein, U. and Walther, W. and Arlt, F. and Schwabe, H. and Smith, J. and Fichtner, I. and Birchmeier, W. and Schlag, P.M.
Nature Medicine 15 (1): 59-67. January 2009

A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl, U. and Worm, U. and Lalowski, M. and Haenig, C. and Brembeck, F.H. and Goehler, H. and Stroedicke, M. and Zenkner, M. and Schoenherr, A. and Koeppen, S. and Timm, J. and Mintzlaff, S. and Abraham, C. and Bock, N. and Kietzmann, S. and Goedde, A. and Toksoez, E. and Droege, A. and Krobitsch, S. and Korn, B. and Birchmeier, W. and Lehrach, H. and Wanker, E.E.
Cell 122 (6): 957-968. 23 September 2005

UroFors: Konstituierung eines Interessensverbundes fuer Naturwissenschaftler in der urologischen Forschung [UroFors: establishment of an interest group for natural scientists in urological research].
Stope, M.B. and Dansranjavin, T. and Erb, H. and Erdmann, K. and Fendler, A. and Hoelters, S. and Juengel, E. and Nitschke, K. and Salomo, K. and Seidel, P. and Skowron, M.A. and Wach, S. and Becker, C.
Urologe 56 (4): 515-518. April 2017

Embryonic hair follicle fate change by augmented β-catenin through Shh and Bmp signaling.
Suzuki, K. and Yamaguchi, Y. and Villacorte, M. and Mihara, K. and Akiyama, M. and Shimizu, H. and Taketo, M.M. and Nakagata, N. and Tsukiyama, T. and Yamaguchi, T.P. and Birchmeier, W. and Kato, S. and Yamada, G.
Development 136 (3): 367-372. February 2009

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta-catenin is not required for the shift.
Takeda, H. and Nagafuchi, A. and Yonemura, S. and Tsukita, S. and Behrens, J. and Birchmeier, W. and Tsukita, S.
Journal of Cell Biology 131 (6 Pt. 2): 1839-1847. December 1995

Role of Epiprofin, a zinc-finger transcription factor, in limb development.
Talamillo, A. and Delgado, I. and Nakamura, T. and de-Vega, S. and Yoshitomi, Y. and Unda, F. and Birchmeier, W. and Yamada, Y. and Ros, M.A.
Developmental Biology 337 (2): 363-374. 15 January 2010

beta-catenin-dependent and -independent effects of deltaN-plakoglobin on epidermal growth and differentiation.
Teuliere, J. and Faraldo, M.M. and Shtutman, M. and Birchmeier, W. and Huelsken, J. and Thiery, J.P. and Glukhova, M.A.
Molecular and Cellular Biology 24 (19): 8649-8661. 1 October 2004

RNF4-dependent oncogene activation by protein stabilization.
Thomas, J.J. and Abed, M. and Heuberger, J. and Novak, R. and Zohar, Y. and Beltra-Lopez, A.P. and Trausch-Azar, J.S. and Ilagan, M.X.G. and Benhamou, D. and Dittmar, G. and Kopan, R. and Birchmeier, W. and Schwartz, A.L. and Orian, A.
Cell Reports 16 (12): 3388-3400. 20 September 2016

Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a negative tumors.
Ueberham, E. and Glöckner, P. and Göhler, C. and Straub, B.K. and Teupser, D. and Schönig, K. and Braeuning, A. and Höhn, A.K. and Jerchow, B. and Birchmeier, W. and Gaunitz, F. and Arendt, T. and Sansom, O. and Gebhardt, R. and Ueberham, U.
Molecular Cancer Research 13 (2): 239-249. February 2015

Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors.
Valenti, G. and Quinn, H.M. and Heynen, G.J.J.E. and Lan, L. and Holland, J.D. and Vogel, R. and Wulf-Goldenberg, A. and Birchmeier, W.
Cancer Research 77 (8): 2134-2147. 15 April 2017

Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury.
Van Steenwinckel, J. and Schang, A.L. and Krishnan, M.L. and Degos, V. and Delahaye-Duriez, A. and Bokobza, C. and Verdonk, F. and Montane, A. and Sigaut, S. and Hennebert, O. and Lebon, S. and Schwendimann, L. and Le Charpentier, T. and Hassan-Abdi, R. and Ball, G. and Aljabar, P. and Saxena, A. and Holloway, R.K. and Birchmeier, W. and Miron, V. and Rowitch, D. and Chretien, F. and Leconte, C. and Besson, V.C. and Petretto, E.G. and Edwards, A.D. and Hagberg, H. and Soussi-Yanicostas, N. and Fleiss, B. and Gressens, P.
bioRxiv : 334359. 31 May 2018

Spatially restricted stromal Wnt signaling restrains prostate epithelial progenitor growth through direct and indirect mechanisms.
Wei, X. and Zhang, L. and Zhou, Z. and Kwon, O.J. and Zhang, Y. and Nguyen, H. and Dumpit, R. and True, L. and Nelson, P. and Dong, B. and Xue, W. and Birchmeier, W. and Taketo, M.M. and Xu, F. and Creighton, C.J. and Ittmann, M.M. and Xin, L.
Cell Stem Cell 24 (5): 753-768. 2 May 2019

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Weidner, K.M. and Dicesare, S. and Sachs, M. and Brinkmann, V. and Behrens, J. and Birchmeier, W.
Nature 384 (6605): 173-176. 14 November 1996

The Met receptor tyrosine kinase transduces motility, proliferation, andmorphogenic signals of scatter factor/ hepatocyte growth factor in epithelial cells.
Weidner, K.M. and Sachs, M. and Birchmeier, W.
Journal of Cell Biology 121 (1): 145-154. April 1993

Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.
Wend, P. and Fang, L. and Zhu, Q. and Schipper, J.H. and Loddenkemper, C. and Kosel, F. and Brinkmann, V. and Eckert, K. and Hindersin, S. and Holland, J.D. and Lehr, S. and Kahn, M. and Ziebold, U. and Birchmeier, W.
EMBO Journal 32 (14): 1977-1989. 17 July 2013

Wnt signaling in stem and cancer stem cells.
Wend, P. and Holland, J.D. and Ziebold, U. and Birchmeier, W.
Seminars in Cell & Developmental Biology 21 (8): 855-863. October 2010

Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization.
Weng, Q. and Wang, J. and Wang, J. and Wang, J. and Sattar, F. and Zhang, Z. and Zheng, J. and Xu, Z. and Zhao, M. and Liu, X. and Yang, L. and Hao, G. and Fang, L. and Lu, Q.R. and Yang, B. and He, Q.
Cell Death & Disease 9 (2): 251. 14 February 2018

The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer.
White, N.M.A. and Youssef, Y.M. and Fendler, A. and Stephan, C. and Jung, K. and Yousef, G.M.
Biological Chemistry 393 (5): 379-389. May 2012

The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling.
Wijk, N.V. and Witte, F. and Feike, A.C. and Schambony, A. and Birchmeier, W. and Mundlos, S. and Stricker, S.
Biochemical and Biophysical Research Communications 390 (2): 211-216. 11 December 2009

The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney.
Willecke, R. and Heuberger, J. and Grossmann, K. and Michos, O. and Schmidt-Ott, K. and Walentin, K. and Costantini, F. and Birchmeier, W.
Developmental Biology 360 (2): 310-307. 15 December 2011

Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach.
Winter, A. and Sigurdardottir, A.G. and DiCara, D. and Valenti, G. and Blundell, T.L. and Gherardi, E.
Molecular Cancer Therapeutics 15 (1): 3-14. January 2016

Deletion of beta-catenin impairs T cell development.
Xu, Y. and Banerjee, D. and Huelsken, J. and Birchmeier, W. and Sen, J.M.
Nature Immunology 4 (12): 1177-1182. 1 January 2003

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.
Yang, Y. and Spitzer, E. and Meyer, D. and Sachs, M. and Niemann, C. and Hartmann, G. and Weidner, K.M. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 131 (1): 215-226. October 1995

Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.
Yoshida, T. and Iwata, T. and Takai, Y. and Birchmeier, W. and Yamato, M. and Okano, T.
Genes to Cells 19 (11): 842-852. November 2014

The role of Axin2 in calvarial morphogenesis and craniosynostosis.
Yu, H.M. and Jerchow, B. and Sheu, T.J. and Liu, B. and Costantini, F. and Puzas, J.E. and Birchmeier, W. and Hsu, W.
Development 132 (8): 1995-2005. 1 January 2005

The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis.
Zatula, N. and Wiese, M. and Bunzendahl, J. and Birchmeier, W. and Perske, C. and Bleckmann, A. and Brembeck, F.H.
Oncotarget 5 (16): 6770-6787. 30 August 2014

Deciphering the function of signaling pathways by tissue specific gene modification in mice.
Zechner, D. and Soshnikova, N. and Birchmeier, W.
Zellbiologie Aktuell 30 (1): 6-8. January 2004

Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Zechner, D. and Muller, T. and Wende, H. and Walther, I. and Taketo, M.M. and Crenshaw, E.B. and Treier, M. and Birchmeier, W. and Birchmeier, C.
Developmental Biology 303 (1): 181-190. 1 March 2007

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender, A. and Huang, J. and Györfi, A.H. and Matei, A.E. and Trinh-Minh, T. and Xu, X. and Li, Y.N. and Chen, C.W. and Lin, J. and Dees, C. and Beyer, C. and Gelse, K. and Zhang, Z.Y. and Bergmann, C. and Ramming, A. and Birchmeier, W. and Distler, O. and Schett, G. and Distler, J.H.W.
Nature Communications 9 (1): 3259. 14 August 2018

Reciprocal requirements for EDA/EDAR/NF-κB and Wnt/β-catenin signaling pathways in hair follicle induction.
Zhang, Y. and Tomann, P. and Andl, T. and Gallant, N.M. and Huelsken, J. and Jerchow, B. and Birchmeier, W. and Paus, R. and Piccolo, S. and Mikkola, M.L. and Morrisey, E.E. and Overbeek, P.A. and Scheidereit, C. and Millar, S.E. and Schmidt-Ullrich, R.
Developmental Cell 17 (1): 49-61. 21 July 2009

The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer.
Zhu, Q. and Fang, L. and Heuberger, J. and Kranz, A. and Schipper, J. and Scheckenbach, K. and Oliveira Vidal, R. and Sunaga-Franze, D.Y. and Müller, M. and Wulf-Goldenberg, A. and Sauer, S. and Birchmeier, W.
Cell Reports 26 (2): 415-428. 8 January 2019

Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.
van den Akker, E. and van Dijk, T. and Parren-van Amelsvoort, M. and Grossmann, K.S. and Schaeper, U. and Toney-Earley, K. and Waltz, S.E. and Loewenberg, B. and von Lindern, M.
Blood 103 (12): 4457-4465. 1 January 2004

Birchmeier-Kohler, Carmen

Molecular aspects of mesenchymal-epithelial interactions.
Birchmeier, C. and Birchmeier, W.
Annual Review of Cell Biology 9 : 511-540. 1993

Met, metastasis, motility and more.
Birchmeier, C. and Birchmeier, W. and Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003

c-Met is essential for wound healing in the skin.
Chmielowiec, J. and Borowiak, M. and Morkel, M. and Stradal, T. and Munz, B. and Werner, S. and Wehland, J. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. and Rom, A. and Franke, V. and Imami, K. and Arrey, G. and Terne, M. and Woehler, A. and Akalin, A. and Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Targeting MET in cancer: rationale and progress.
Gherardi, E. and Birchmeier, W. and Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M. and Yu, Y. and Liang, L. and Vuralli, D. and Froehler, S. and Kuehnen, P. and Du Bois, P. and Zhang, J. and Cao, A. and Liu, Y. and Hussain, K. and Fielitz, J. and Jia, S. and Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7 (5): e602. May 2019

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T. and Stein, S. and Qi, J. and Wende, H. and Garratt, A.N. and Nave, K.A. and Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S. and Rosario, M. and Birchmeier, C. and Birchmeier, W.
Advances in Cancer Research 106 : 53-89. 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J. and Vogel, R. and Brinkmann, V. and Erdmann, B. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 148 (3): 567-578. 7 February 2000

Negative regulation of Ros receptor tyrosine kinase signaling: An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
Keilhack, H. and Mueller, M. and Boehmer, S.A. and Frank, C. and Weidner, K.M. and Birchmeier, W. and Ligensa, T. and Berndt, A. and Kosmehl, H. and Gunther, B. and Mueller, T. and Birchmeier, C. and Boehmer, F.D.
Journal of Cell Biology 152 (2): 325-334. 22 January 2001

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M. and Wende, H. and Walcher, J. and Kühnemund, J. and Cheret, C. and Kempa, S. and McShane, E. and Selbach, M. and Lewin, G.R. and Birchmeier, C.
Genes & Development 32 (9-10): 645-657. 10 May 2018

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I. and Bröhl, D. and Zyrianova, T. and Isomura, A. and Czajkowski, M.T. and Kapoor, V. and Griger, J. and Ruffault, P.L. and Mademtzoglou, D. and Zammit, P.S. and Wunderlich, T. and Spuler, S. and Kühn, R. and Preibisch, S. and Wolf, J. and Kageyama, R. and Birchmeier, C.
Genes & Development 33 (9-10): 524-535. 1 May 2019

Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met.
Marx-Stoelting, P. and Borowiak, M. and Knorpp, T. and Birchmeier, C. and Buchmann, A. and Schwarz, M.
International Journal of Cancer 124 (8): 1767-1772. 15 April 2009

EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake.
Matthäus, C. and Lahmann, I. and Kunz, S. and Jonas, W. and Alves Melo, A. and Lehmann, M. and Larsson, E. and Lundmark, R. and Kern, M. and Blüher, M. and Müller, D.N. and Haucke, V. and Schürmann, A. and Birchmeier, C. and Daumke, O.
bioRxiv : 511709. 7 March 2019

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. and Kirchner, M. and Uyar, B. and Cheng, J.Y. and Russo, G. and Hernandez-Miranda, L.R. and Szymborska, A. and Zauber, H. and Rudolph, I.M. and Willnow, T.E. and Akalin, A. and Haucke, V. and Gerhardt, H. and Birchmeier, C. and Kühn, R. and Krauss, M. and Diecke, S. and Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M. and Glažar, P. and Hernandez-Miranda, L.R. and Memczak, S. and Wolf, S.A. and Rybak-Wolf, A. and Filipchyk, A. and Klironomos, F. and Cerda Jara, C.A. and Fenske, P. and Trimbuch, T. and Zywitza, V. and Plass, M. and Schreyer, L. and Ayoub, S. and Kocks, C. and Kühn, R. and Rosenmund, C. and Birchmeier, C. and Rajewsky, N.
Science 357 (6357): eaam8526. 22 September 2017

Biochemical and functional characterization of the murine ros protooncogene.
Riethmacher, D. and Langholz, O. and Goedecke, S. and Sachs, M. and Birchmeier, C.
Oncogene 9 (12): 3617-3626. December 1994

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
Ruiz, P. and Brinkmann, V. and Ledermann, B. and Behrend, M. and Grund, C. and Thalhammer, C. and Vogel, F. and Birchmeier, C. and Guenthert, U. and Franke, W.W. and Birchmeier, W.
Journal of Cell Biology 135 (1): 215-225. October 1996

Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Sachs, M. and Brohmann, H. and Zechner, D. and Mueller, T. and Huelsken, J. and Walther, I. and Schaeper, U. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 150 (6): 1375-1384. 18 September 2000

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E. and McShane, E. and Cheret, C. and Walcher, J. and Müller, T. and Wulf-Goldenberg, A. and Hoelper, S. and Garratt, A.N. and Krüger, M. and Rajewsky, K. and Meijer, D. and Birchmeier, W. and Lewin, G.R. and Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

Recessive mutations in PCBD1 cause a new type of early-onset diabetes.
Simaite, D. and Kofent, J. and Gong, M. and Rüschendorf, F. and Jia, S. and Arn, P. and Bentler, K. and Ellaway, C. and Kühnen, P. and Hoffmann, G.F. and Blau, N. and Spagnoli, F.M. and Hübner, N. and Raile, K.
Diabetes 63 (10): 3557-3564. October 2014

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.
Yang, Y. and Spitzer, E. and Meyer, D. and Sachs, M. and Niemann, C. and Hartmann, G. and Weidner, K.M. and Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 131 (1): 215-226. October 1995

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Zechner, D. and Muller, T. and Wende, H. and Walther, I. and Taketo, M.M. and Crenshaw, E.B. and Treier, M. and Birchmeier, W. and Birchmeier, C.
Developmental Biology 303 (1): 181-190. 1 March 2007

Blankenstein, Thomas

T cell homing to tumors detected by 3D-coordinated positron emission tomography and magnetic resonance imaging.
Agger, R. and Petersen, M.S. and Petersen, C.C. and Hansen, S.B. and Stodkilde-Jorgensen, H. and Skands, U. and Blankenstein, T. and Andersen, T.E. and Hulgaard, E.F. and Jorgensen, J.T. and Marqversen, J. and Gundersen, H.J. and Hokland, M.E.
Journal of Immunotherapy 30 (1): 29-39. January 2007

Nicotine strongly activates dendritic cell-mediated adaptive immunity - Potential role for progression of atherosclerotic lesions.
Aicher, A. and Heeschen, C. and Mohaupt, M. and Cooke, J.P. and Zeiher, A.M. and Dimmeler, S.
Circulation 107 (4): 604-611. 4 February 2003

Molecular pathways: comparing the effects of drugs and T cells to effectively target oncogenes.
Anders, K. and Blankenstein, T.
Clinical Cancer Research 19 (2): 320-326. 15 January 2013

Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.
Anders, K. and Buschow, C. and Charo, J. and Blankenstein, T.
Transgenic Research 21 (5): 1099-1107. October 2012

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K. and Buschow, C. and Herrmann, A. and Milojkovic, A. and Loddenkemper, C. and Kammertoens, T. and Daniel, P. and Yu, H. and Charo, J. and Blankenstein, T.
Cancer Cell 20 (6): 755-767. 13 December 2011

The immune system prevents recurrence of transplanted but not autochthonous antigenic tumors after oncogene inactivation therapy.
Anders, K. and Kershaw, O. and Larue, L. and Gruber, A.D. and Blankenstein, T.
International Journal of Cancer 141 (12): 2551-2561. 15 December 2017

Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome.
Babaylova, E. and Graifer, D. and Malygin, A. and Stahl, J. and Shatsky, I. and Karpova, G.
Nucleic Acids Research 37 (4): 1141-1151. March 2009

Receptor combinations hone T-cell therapy.
Blankenstein, T.
Nature Biotechnology 34 (4): 389-391. 7 April 2016

Spontaneous and therapy-induced T cell responses to cancer.
Blankenstein, T.
Arzneimittelforschung 62 (1): S9. November 2012

Do autochthonous tumors interfere with effector T cell responses?
Blankenstein, T.
Seminars in Cancer Biology 17 (4): 267-274. August 2007

The role of tumor stroma in the interaction between tumor and immune system.
Blankenstein, T.
Current Opinion in Immunology 17 (2): 180-186. 1 January 2005

The role of inflammation for tumour growth and tumour suppression.
Blankenstein, T.
In: Cancer and inflammation : Symposium on Cancer and Inflammation, held at the Novartis Foundation, London, 12-14 November 2002. Novartis Foundation Symposium ; 256 . Wiley, Hoboken, N.J., 205-210. ISBN 0-470-85510-X 23 January 2004

Genetic approaches to cancer immunotherapy.
Blankenstein, T. and Cayeux, S. and Qin, Z.
Reviews of Physiology Biochemistry and Pharmacology 129 : 1-49. 1 January 1996

Lebendvakzine gegen Tumorerkrankungen.
Blankenstein, T. and Cayeux-Pezzutto, S.
DE4431401A1. 29 February 1996

The determinants of tumour immunogenicity.
Blankenstein, T. and Coulie, P.G. and Gilboa, E. and Jaffee, E.M.
Nature Reviews Cancer 12 (4): 307-313. April 2012

Targeting cancer-specific mutations by T cell receptor gene therapy.
Blankenstein, T. and Leisegang, M. and Uckert, W. and Schreiber, H.
Current Opinion in Immunology 33 : 112-119. April 2015

Chemical carcinogens as foreign bodies and some pitfalls regarding cancer immune surveillance.
Blankenstein, T. and Qin, Z.
Advances in Cancer Research 90 : 179-207. 2003

The role of IFN-gamma in tumor transplantation immunity and inhibition of chemical carcinogenesis.
Blankenstein, T. and Qin, Z.H.
Current Opinion in Immunology 15 (2): 148-154. April 2003

Lebendvakzine zur Behandlung von Tumorerkrankungen [Live vaccine for the treatment of tumour diseases].
T. Blankenstein, S. Cayeux.
EP0777499A1 ; EP0777499B1 ; WO9605866A2 ; WO9605866A3 ; US6,039,941. 11 June 1997

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J. and Kieback, E. and Marino, S.F. and Oden, F. and Westermann, J. and Chmielewski, M. and Abken, H. and Uckert, W. and Höpken, U.E. and Rehm, A.
Molecular Therapy 26 (8): 1906-1920. 1 August 2018

Visceral leishmaniasis diagnosis and reporting delays as an obstacle to timely response actions in Nepal and India.
Boettcher, J.P. and Siwakoti, Y. and Milojkovic, A. and Siddiqui, N.A. and Gurung, C.K. and Rijal, S. and Das, P. and Kroeger, A. and Banjara, M.R.
BMC Infectious Diseases 15 (1): 43. 6 February 2015

Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates.
Briesemeister, D. and Friese, C. and Isern, C.C. and Dietz, E. and Blankenstein, T. and Thoene-Reineke, C. and Kammertoens, T.
Cytokine 60 (3): 626-633. December 2012

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis.
Briesemeister, D. and Sommermeyer, D. and Loddenkemper, C. and Loew, R. and Uckert, W. and Blankenstein, T. and Kammertoens, T.
International Journal of Cancer 128 (2): 371-378. 15 January 2011

Phase I trial of an allogeneic gene-modified tumor cell vaccine (RCC-26/CD80/IL-2) in patients with metastatic renal cell carcinoma.
Buchner, A. and Pohla, H. and Willimsky, G. and Frankenberger, B. and Frank, R. and Baur-Melnyk, A. and Siebels, M. and Stief, C.G. and Hofstetter, A. and Kopp, J. and Pezzutto, A. and Blankenstein, T. and Oberneder, R. and Schendel, D.J.
Human Gene Therapy 21 (3): 285-297. March 2010

In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance.
Buschow, C. and Charo, J. and Anders, K. and Loddenkemper, C. and Jukica, A. and Alsamah, W. and Perez, C. and Willimsky, G. and Blankenstein, T.
Journal of Immunology 184 (6): 2930-2938. 15 March 2010

In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine.
Cayeux, S. and Bukarica, B. and Buschow, C. and Charo, J. and Bunse, M. and Doerken, B. and Blankenstein, T.
Gene Therapy 14 (20): 1481-1491. October 2007

Visualizing the dynamic of adoptively transferred T cells during the rejection of large established tumors.
Charo, J. and Perez, C. and Buschow, C. and Jukica, A. and Czeh, M. and Blankenstein, T.
European Journal of Immunology 41 (11): 3187-3197. November 2011

Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X. and Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214 (11): 3417-3433. 6 November 2017

Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
Chumduri, C. and Gillissen, B. and Richter, A. and Richter, A. and Milojkovic, A. and Overkamp, T. and Mueller, A. and Pott, C. and Daniel, P.T.
Journal of Molecular Medicine 93 (5): 559-572. May 2015

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR.
Clauss, J. and Obenaus, M. and Miskey, C. and Ivics, Z. and Izsvák, Z. and Uckert, W. and Bunse, M.
Human Gene Therapy 29 (5): 569-584. May 2018

The immune response to sporadic colorectal cancer in a novel mouse model.
Czeh, M. and Loddenkemper, C. and Shalapour, S. and Schoen, C. and Robine, S. and Goldscheid, E. and Stein, H. and Schueler, T. and Willimsky, G. and Blankenstein, T.
Oncogene 29 (50): 6591-6602. 16 December 2010

Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.
Daniel, P.T. and Kroidl, A. and Cayeux, S. and Bargou, R.C. and Blankenstein, T. and Doerken, B.
Journal of Immunology 159 (8): 3808-3815. 15 October 1997

Interleukin-7 modulates anti-tumor CD8+ T cell responses via its action on host cells.
Deiser, K. and Stoycheva, D. and Bank, U. and Blankenstein, T. and Schüler, T.
PLoS ONE 11 (7): e0159690. 22 July 2016

Retroviral vectors for high-level transgene expression in T lymphocytes.
Engels, B. and Cam, H. and Schueler, T. and Indraccolo, S. and Gladow, M. and Baum, C. and Blankenstein, T. and Uckert, W.
Human Gene Therapy 14 (12): 1155-1168. 10 August 2003

Redirecting human T lymphocytes toward renal cell carcinoma specificity by retroviral transfer of T cell receptor genes.
Engels, B. and Noessner, E. and Frankenberger, B. and Blankenstein, T. and Schendel, D.J. and Uckert, W.
Human Gene Therapy 16 (7): 799-810. 1 July 2005

Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken, A. and Grau, M. and Wolf, A. and Weilemann, A. and Kopp, J. and Dörken, B. and Blankenstein, T. and Pezzutto, A. and Lenz, P. and Lenz, G. and Westermann, J.
International Journal of Cancer 136 (8): 1814-1826. 15 April 2015

Influence of CD80, interleukin-2, and interleukin-7 expression in human renal cell carcinoma on the expansion, function, and survival of tumor-specific CTLs.
Frankenberger, B. and Pohla, H. and Noessner, E. and Willimsky, G. and Papier, B. and Pezzutto, A. and Kopp, J. and Oberneder, R. and Blankenstein, T. and Schendel, D.J.
Clinical Cancer Research 11 : 1733-1742. 1 January 2005

Cell-based vaccines for renal cell carcinoma: genetically-engineered tumor cells and monocyte-derived dendritic cells.
Frankenberger, B. and Regn, S. and Geiger, C. and Noessner, E. and Falk, C.S. and Pohla, H. and Javorovic, M. and Silberzahn, T. and Wilde, S. and Buchner, A. and Siebels, M. and Oberneder, R. and Willimsky, G. and Pezzutto, A. and Blankenstein, T. and Schendel, D.J.
World Journal of Urology 23 (3): 166-174. 5 July 2005

A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells.
Gavvovidis, I. and Rost, I. and Trimborn, M. and Kaiser, F.J. and Purps, J. and Wiek, C. and Hanenberg, H. and Neitzel, H. and Schindler, D.
PLoS ONE 7 (8): e40387. 30 August 2012

Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.
Gavvovidis, I. and Leisegang, M. and Willimsky, G. and Miller, N.J. and Nghiem, P. and Blankenstein, T.
Clinical Cancer Research 24 (15): 3644-3655. August 2018

Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.
Gerbitz, A. and Sukumar, M. and Helm, F. and Wilke, A. and Friese, C. and Fahrenwaldt, C. and Lehmann, F.M. and Loddenkemper, C. and Kammertoens, T. and Mautner, J. and Schmitt, C.A. and Blankenstein, T. and Bornkamm, G.W.
PLoS ONE 7 (3): e34552. 30 March 2012

Dual T cell receptor T cells with two defined specificities mediate tumor suppression via both receptors.
Gladow, M. and Uckert, W. and Blankenstein, T.
European Journal of Immunology 34 (7): 1882-1891. 1 July 2004

Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit.
Grosheva, A.S. and Zharkov, D.O. and Stahl, J. and Gopanenko, Al.V. and Tupikin, A.E. and Kabilov, M.R. and Graifer, D.M. and Karpova, G.G.
Nucleic Acids Research 45 (7): 3833-3843. 20 April 2017

Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT.
Hayashida, N. and Fujimoto, M. and Tan, K. and Prakasam, R. and Shinkawa, T. and Li, L. and Ichikawa, H. and Takii, R. and Nakai, A.
EMBO Journal 29 (20): 3459-3469. 20 October 2010

CTLA4 promotes Tyk2-STAT3 dependent B-cell oncogenecity.
Herrmann, A. and Lahtz, C. and Nagao, T. and Song, J.Y. and Chan, W.C. and Lee, H. and Yue, C. and Look, T. and Muelfarth, R. and Li, W. and Jenkins, K. and Williams, J. and Budde, L.E. and Forman, S.J. and Kwak, L.W. and Blankenstein, T. and Yu, H.
Cancer Research 77 (18): 5118-5128. 15 September 2017

Vaccine-instructed intratumoral IFN-γ enables regression of autochthonous mouse prostate cancer in allogeneic T cell transplantation.
Hess Michelini, R. and Manzo, T. and Sturmheit, T. and Basso, V. and Rocchi, M. and Freschi, M. and Listopad, J.J. and Blankenstein, T. and Bellone, M. and Mondino, A.
Cancer Research 73 (15): 4641-4652. 1 August 2013

Vaccinations with tumor cells genetically engineered to produce different cytokines: effectivity not superior to a classical adjuvant.
Hock, H. and Dorsch, M. and Kunzendorf, U. and Ueberla, K. and Qin, Z. and Diamantstein, T. and Blankenstein, T.
Cancer Research 53 (4): 714-716. 15 February 1993

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D. and Schön, C. and Loddenkemper, C. and Lohneis, P. and Kühl, A.A. and Sommermann, T. and Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

Tumor rejection by disturbing tumor stroma cell interactions.
Ibe, S. and Qin, Z.H. and Schueler, T. and Preiss, S. and Blankenstein, T.
Journal of Experimental Medicine 194 (11): 1549-1559. 3 December 2001

Strong immunogenic potential of a B7 retroviral expression vector: Generation of HLA-B7-restricted CTL response against selectable marker genes.
Jung, D. and Jaeger, E. and Cayeux, S. and Blankenstein, T. and Hilmes, C. and Karbach, J. and Moebius, U. and Knuth, A. and Huber, C. and Seliger, B.
Human Gene Therapy 9 : 53-62. 1 January 1998

It's the peptide-MHC affinity, stupid.
Kammertoens, T. and Blankenstein, T.
Cancer Cell 23 (4): 429-431. 15 April 2013

Making and circumventing tolerance to cancer.
Kammertoens, T. and Blankenstein, T.
European Journal of Immunology 39 (9): 2345-2353. September 2009

B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin).
Kammertoens, T. and Qin, Z. and Briesemeister, D. and Bendelac, A. and Blankenstein, T.
International Journal of Cancer 131 (7): 1499-1508. 1 October 2012

Immunotherapy: target the stroma to hit the tumor.
Kammertoens, T. and Schueler, T. and Blankenstein, T.
Trends in Molecular Medicine 11 (5): 225-231. 1 January 2005

CY15, a malignant histiocytic tumor that is phenotypically similar to immature dendritic cells.
Kammertoens, T. and Willebrand, R. and Erdmann, B. and Li, L. and Li, Y. and Engels, B. and Uckert, W. and Blankenstein, T.
Cancer Research 65 : 2560-2564. 1 January 2005

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. and Friese, C. and Arina, A. and Idel, C. and Briesemeister, D. and Rothe, M. and Ivanov, A. and Szymborska, A. and Patone, G. and Kunz, S. and Sommermeyer, D. and Engels, B. and Leisegang, M. and Textor, A. and Fehling, H.J. and Fruttiger, M. and Lohoff, M. and Herrmann, A. and Yu, H. and Weichselbaum, R. and Uckert, W. and Hübner, N. and Gerhardt, H. and Beule, D. and Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

Protein S3 fragments neighboring mRNA during elongation and termination of translation on the human ribosome.
Khairulina, Y.S. and Molotkov, M.V. and Bulygin, K.N. and Graifer, D.M. and Ven’yaminova, A.G. and Frolova, L.Y. and Stahl, J. and Karpova, G.G.
Russian Journal of Bioorganic Chemistry 34 (6): 691-697. November 2008

A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer.
Kieback, E. and Charo, J. and Sommermeyer, D. and Blankenstein, T. and Uckert, W.
Proceedings of the National Academy of Sciences of the United States of America 105 (2): 623-628. 15 January 2008

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity.
Kieback, E. and Hilgenberg, E. and Stervbo, U. and Lampropoulou, V. and Shen, P. and Bunse, M. and Jaimes, Y. and Boudinot, P. and Radbruch, A. and Klemm, U. and Kühl, A.A. and Liblau, R. and Hoevelmeyer, N. and Anderton, S.M. and Uckert, W. and Fillatreau, S.
Immunity 44 (5): 1114-1126. 17 May 2016

Establishment of early lymphoid organ infrastructure in transplanted tumors mediated by local production of lymphotoxin alpha and in the combined absence of functional B and T cells.
Kim, H.J. and Kammertoens, T. and Janke, M. and Schmetzer, O. and Qin, Z. and Berek, C. and Blankenstein, T.
Journal of Immunology 172 (7): 4037-4047. 1 January 2004

Interferon-γ receptor signaling in dendritic cells restrains spontaneous proliferation of CD4(+) T cells in chronic lymphopenic mice.
Knop, L. and Frommer, C. and Stoycheva, D. and Deiser, K. and Kalinke, U. and Blankenstein, T. and Kammertoens, T. and Dunay, I.R. and Schüler, T.
Frontiers in Immunology 10 : 140. 7 February 2019

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.
Kruschinski, A. and Moosmann, A. and Poschke, I. and Norell, H. and Chmielewski, M. and Seliger, B. and Kiessling, R. and Blankenstein, T. and Abken, H. and Charo, J.
Proceedings of the National Academy of Sciences of the United States of America 105 (45): 17481-17486. 11 November 2008

T cell receptors for clinical therapy: in vitro assessment of toxicity risk.
Kunert, A. and Obenaus, M. and Lamers, C.H.J. and Blankenstein, T. and Debets, R.
Clinical Cancer Research 23 (20): 6012-6020. 15 October 2017

Ablation of TNF or lymphotoxin signaling and the frequency of spontaneous tumors in p53-deficient mice.
Kuprash, D.V. and Qin, Z. and Ito, D. and Grivennikov, S.I. and Abe, K. and Drutskaya, L.N. and Blankenstein, T. and Nedospasov, S.A.
Cancer Letters 268 (1): 70-75. 8 September 2008

A synthetic peptide homologous to functional domain of human IL-10 down-regulates expression of MHC class I and transporter associated with antigen processing 1/2 in human melanoma cells.
Kurte, M. and Lopez, M. and Aguirre, A. and Escobar, A. and Aguillon, J.C. and Charo, J. and Larsen, C.G. and Kiessling, R. and Salazar-Onfray, F.
Journal of Immunology 173 (3): 1731-1737. 1 January 2004

Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels.
Lange, C. and Schueler, T. and Blankenstein, T.
Journal of Experimental Medicine 187 (9): 1487-1493. 4 May 1998

Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice.
Lange, K. and Uckert, W. and Blankenstein, T. and Nadrowitz, R. and Bittner, C. and Renauld, J.C. and van Snick, J. and Feller, A.C. and Merz, H.
Oncogene 22 (4): 517-527. 30 January 2003

T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy.
Leisegang, M. and Turqueti-Neves, A. and Engels, B. and Blankenstein, T. and Schendel, D.J. and Uckert, W. and Noessner, E.
Clinical Cancer Research 16 (8): 2333-2343. 15 April 2010

Targeting human melanoma neoantigens by T cell receptor gene therapy.
Leisegang, M. and Kammertoens, T. and Uckert, W. and Blankenstein, T.
Journal of Clinical Investigation 126 (3): 854-858. 1 March 2016

Generation of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast-embryonic stem cell fusion.
Li, L. and Blankenstein, T.
Nature Protocols 8 (8): 1567-1582. August 2013

Transgenic mice with a diverse human T cell antigen receptor repertoire.
Li, L.P. and Lampert, J.C. and Chen, X. and Leitao, C. and Popovic, J. and Mueller, W. and Blankenstein, T.
Nature Medicine 16 (9): 1029-1034. September 2010

SV40 large T antigen-transformed human primary normal and cancerous mammary epithelial cells are phenotypically similar but can be distinguished in 3D culture with selection medium.
Li, L.P. and Willimsky, G. and Seitz, S. and Xu, Y. and Li, Y. and Schwarz, L.E. and Schlag, P.M. and Blankenstein, T.
International Journal of Cancer 123 (7): 1516-1525. 1 October 2008

CD4+ T cell-mediated HER-2/neu-specific tumor rejection in the absence of B cells.
Lindencrona, J.A. and Preiss, S. and Kammertoens, T. and Schueler, T. and Piechocki, M. and Wei, W.Z. and Seliger, B. and Blankenstein, T. and Kiessling, R.
International Journal of Cancer 109 (2): 259-264. 1 January 2004

High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann, C. and Heemskerk, B. and Kvistborg, P. and Kluin, R.J.C. and Bolotin, D.A. and Chen, X. and Bresser, K. and Nieuwland, M. and Schotte, R. and Michels, S. and Gomez-Eerland, R. and Jahn, L. and Hombrink, P. and Legrand, N. and Shu, C.J. and Mamedov, I.Z. and Velds, A. and Blank, C.U. and Haanen, J.B.A.G. and Turchaninova, M.A. and Kerkhoven, R.M. and Spits, H. and Hadrup, S.R. and Heemskerk, M.H.M. and Blankenstein, T. and Chudakov, D.M. and Bendle, G.M. and Schumacher, T.N.M.
Nature Medicine 19 (11): 1534-1541. November 2013

Fas expression by tumor stroma is required for cancer eradication.
Listopad, J.J. and Kammertoens, T. and Anders, K. and Silkenstedt, B. and Willimsky, G. and Schmidt, K. and Kuehl, A.A. and Loddenkemper, C. and Blankenstein, T.
Proceedings of the National Academy of Sciences of the United States of America 110 (6): 2276-2281. 5 February 2013

IL-10 controls ultraviolet-induced carcinogenesis in mice.
Loser, K. and Apelt, J. and Voskort, M. and Mohaupt, M. and Balkow, S. and Schwarz, T. and Grabbe, S. and Beissert, S.
Journal of Immunology 179 (1): 365-371. 1 July 2007

Die Ueberexpression von NPM-ALK in haematopoietischen Stammzellen induziert verschiedene maligne Non-Hodgkin-Lymphome in der IL-9 transgenen Maus [Overexpression of NPM-ALK induces different types of malignant lymphomas in IL-9 transgenic mice].
Merz, H. and Lange, K. and Nadrowitz, R. and Uckert, W. and Blankenstein, T. and Feller, A.C.
Verhandlungen der Deutschen Gesellschaft fuer Pathologie 87 : 224-231. 1 January 2003

Tumor-infiltrating merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival.
Miller, N.J. and Church, C.D. and Dong, L. and Crispin, D. and Fitzgibbon, M.P. and Lachance, K. and Jing, L. and Shinohara, M. and Gavvovidis, I. and Willimsky, G. and McIntosh, M. and Blankenstein, T. and Koelle, D.M. and Nghiem, P.
Cancer Immunology Research 5 (2): 137-147. February 2017

Transduction efficiency of MLV but not of HIV-1 vectors is pseudotype dependent on human primary T lymphocytes.
Muehlebach, M.D. and Schmitt, I. and Steidl, S. and Stitz, J. and Schweizer, M. and Blankenstein, T. and Cichutek, K. and Uckert, W.
Journal of Molecular Medicine 81 (12): 801-810. December 2003

Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR.
Nassenstein, C. and Kammertoens, T. and Veres, T.Z. and Uckert, W. and Spies, E. and Fuchs, B. and Krug, N. and Braun, A.
Journal of Allergy and Clinical Immunology 120 (5): 1089-1096. November 2007

Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.
Norell, H. and Poschke, I. and Charo, J. and Wei, W.Z. and Erskine, C. and Piechocki, M.P. and Knutson, K.L. and Bergh, J. and Lidbrink, E. and Kiessling, R.
Journal of Translational Medicine 8 (1): 53. 7 June 2010

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice.
Obenaus, M. and Leitão, C. and Leisegang, M. and Chen, X. and Gavvovidis, I. and van der Bruggen, P. and Uckert, W. and Schendel, D.J. and Blankenstein, T.
Nature Biotechnology 33 (4): 402-407. April 2015

CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions.
Ohl, L. and Mohaupt, M. and Czeloth, N. and Hintzen, G. and Kiafard, Z. and Zwirner, J. and Blankenstein, T. and Henning, G. and Foerster, R.
Immunity 21 (2): 279-288. 1 August 2004

Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer.
Penter, L. and Dietze, K. and Ritter, J. and Lammoglia Cobo, M.F. and Garmshausen, J. and Aigner, F. and Bullinger, L. and Hackstein, H. and Wienzek-Lischka, S. and Blankenstein, T. and Hummel, M. and Dornmair, K. and Hansmann, L.
OncoImmunology 8 (6): e1586409. 24 March 2019

Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts.
Perez, C. and Jukica, A. and Listopad, J.J. and Anders, K. and Kühl, A.A. and Loddenkemper, C. and Blankenstein, T. and Charo, J.
International Journal of Cancer 137 (2): 359-371. 15 July 2014

Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells.
Pinto, S. and Sommermeyer, D. and Michel, C. and Wilde, S. and Schendel, D. and Uckert, W. and Blankenstein, T. and Kyewski, B.
European Journal of Immunology 44 (9): 2811-2821. September 2014

High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients after tumor cell vaccination.
Pohla, H. and Buchner, A. and Stadlbauer, B. and Frankenberger, B. and Stevanovic, S. and Walter, S. and Frank, R. and Schwachula, T. and Olek, S. and Kopp, J. and Willimsky, G. and Stief, C.G. and Hofstetter, A. and Pezzutto, A. and Blankenstein, T. and Oberneder, R. and Schendel, D.J.
Molecular Medicine 18 : 1499-1508. 8 February 2013

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.
Poncette, L. and Chen, X. and Lorenz, F.K.M. and Blankenstein, T.
Journal of Clinical Investigation 129 (1): 324-335. 2 January 2019

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic, J. and Li, L.P. and Kloetzel, P.M. and Leisegang, M. and Uckert, W. and Blankenstein, T.
Blood 118 (4): 946-954. 28 July 2011

Tumor-induced antibodies resemble the response to tissue damage.
Preiss, S. and Kammertoens, T. and Lampert, C. and Willimsky, G. and Blankenstein, T.
International Journal of Cancer 115 (3): 456-462. 1 January 2005

Methods for use of cytokine gene-modified tumor cells in immunotherapy of cancer.
Qin, Z. and Blankenstein, T.
Methods in Molecular Medicine 7 : 339-348. 1997

Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis.
Qin, Z. and Krueger-Krasagakes, S. and Kunzendorf, U. and Hock, H. and Diamantstein, T. and Blankenstein, T.
Journal of Experimental Medicine 178 (1): 355-360. 1 July 1993

Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte- macrophage colony-stimulating factor gene-modified tumor cells.
Qin, Z. and Noffz, G. and Mohaupt, M. and Blankenstein, T.
Journal of Immunology 159 (2): 770-776. 15 July 1997

A cancer immunosurveillance controversy.
Qin, Z.H. and Blankenstein, T.
Nature Immunology 5 (1): 3-4. 1 January 2004

A critical requirement of interferon gamma-mediated angiostasis for tumor rejection by CD8T cells.
Qin, Z.H. and Schwartzkopff, J. and Pradera, F. and Kammertoens, T. and Seliger, B. and Pircher, H. and Blankenstein, T.
Cancer Research 63 (14): 4095-4100. 1 January 2003

Inhibition of methylcholanthrene-induced carcinogenesis by an interferon gamma receptor-dependent foreign body reaction.
Qin, Z. and Kim, H.J. and Hemme, J. and Blankenstein, T.
Journal of Experimental Medicine 195 (11): 1479-1490. 3 June 2002

Interleukin 10 transfected into Chinese hamster ovary cells prevents tumor growth and macrophage infiltration.
Richter, G. and Krueger-Krasagakes, S. and Hein, G. and Huels, C. and Schmitt, E. and Diamantstein, T. and Blankenstein, T.
Cancer Research 53 (18): 4134-4137. 15 September 1993

Induction of PSA-specific CTLs and anti-tumor immunity by a genetic prostate cancer vaccine.
Roos, A.K. and Pavlenko, M. and Charo, J. and Egevad, L. and Pisa, P.
Prostate 62 (3): 217-223. 1 January 2005

IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis.
Rothe, M. and Quarcoo, D. and Chashchina, A.A. and Bozrova, S.V. and Qin, Z. and Nedospasov, S.A. and Blankenstein, T. and Kammertoens, T. and Drutskaya, M.S.
Cancer Medicine 2 (6): 815-825. December 2013

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
Schmidt, K. and Zilio, S. and Schmollinger, J.C. and Bronte, V. and Blankenstein, T. and Willimsky, G.
Blood 121 (10): 1740-1748. 7 March 2013

ERAP1-dependent antigen cross-presentation determines efficacy of adoptive T cell therapy in mice.
Schmidt, K. and Keller, C. and Kühl, A.A. and Textor, A. and Seifert, U. and Blankenstein, T. and Willimsky, G. and Kloetzel, P.M.
Cancer Research 78 (12): 3243-3254. June 2018

Cutting edge: CD8+ effector T cells reject tumors by direct antigen recognition but indirect action on host cells.
Schueler, T. and Blankenstein, T.
Journal of Immunology 170 (9): 4427-4431. 1 May 2003

Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8+ T cells.
Schueler, T. and Kammertoens, T. and Preiss, S. and Debs, P. and Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 194 (12): 1767-1775. 17 December 2001

Tumor rejection by modulation of tumor stromal fibroblasts.
Schueler, T. and Koernig, S. and Blankenstein, T.
Journal of Experimental Medicine 198 (10): 1487-1493. 17 November 2003

T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice.
Schueler, T. and Qin, Z. and Ibe, S. and Noben-Trauth, N. and Blankenstein, T.
Journal of Experimental Medicine 189 (5): 803-810. 1 March 1999

SigsPack, a package for cancer mutational signatures.
Schumann, F. and Blanc, E. and Messerschmidt, C. and Blankenstein, T. and Busse, A. and Beule, D.
BMC Bioinformatics 20 (1): 450. 2 September 2019

Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo.
Shalapour, S. and Deiser, K. and Sercan, O. and Tuckermann, J. and Minnich, K. and Willimsky, G. and Blankenstein, T. and Haemmerling, G.J. and Arnold, B. and Schueler, T.
European Journal of Immunology 40 (9): 2391-2400. September 2010

Leukemia-associated genetic aberrations in mesenchymal stem cells of children with acute lymphoblastic leukemia.
Shalapour, S. and Eckert, C. and Seeger, K. and Pfau, M. and Prada, J. and Henze, G. and Blankenstein, T. and Kammertoens, T.
Journal of Molecular Medicine 88 (3): 249-265. March 2010

Molecular contacts of ribose-phosphate backbone of mRNA with human ribosome.
Sharifulin, D.E. and Grosheva, A.S. and Bartuli, Y.S. and Malygin, A.A. and Meschaninova, M.I. and Ven'yaminova, A.G. and Stahl, J. and Graifer, D.M. and Karpova, G.G.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1849 (8): 930-939. August 2015

Designer T cells by T cell receptor replacement.
Sommermeyer, D. and Neudorfer, J. and Weinhold, M. and Leisegang, M. and Engels, B. and Noessner, E. and Heemskerk, M.H. and Charo, J. and Schendel, D.J. and Blankenstein, T. and Bernhard, H. and Uckert, W.
European Journal of Immunology 36 (11): 3052-3059. November 2006

Necrotic death but not irradiation abolishes costimulation of T-cell effector functions and survival by CD80-expressing tumor cells.
Staerck, L. and Scholz, C. and Blankenstein, T. and Doerken, B. and Daniel, P.T.
International Journal of Cancer 116 (1): 78-86. 1 January 2005

Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation induces a CD8+ T cell-mediated graft-versus-tumor effect that is independent of the recognition of alloantigenic tumor targets.
Stelljes, M. and Strothotte, R. and Pauels, H.G. and Poremba, C. and Milse, M. and Specht, C. and Albring, J. and Bisping, G. and Scheffold, C. and Kammertoens, T. and Oelmann, E. and Silling, G. and Berdel, W.E. and Kienast, J.
Blood 104 (4): 1210-1216. 1 January 2004

A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo.
Szyska, M. and Herda, S. and Althoff, S. and Heimann, A. and Russ, J. and D'Abundo, D. and Dang, T.M. and Durieux, I. and Dörken, B. and Blankenstein, T. and Na, I.K.
Cancer Immunology Research 6 (1): 110-120. January 2018

Efficacy of CAR T-cell therapy in large tumors relies upon stromal targeting by IFNγ.
Textor, A. and Listopad, J.J. and Wührmann, L.L. and Perez, C. and Kruschinski, A. and Chmielewski, M. and Abken, H. and Blankenstein, T. and Charo, J.
Cancer Research 74 (23): 6796-6805. 1 December 2014

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Textor, A. and Schmidt, K. and Kloetzel, P.M. and Weißbrich, B. and Perez, C. and Charo, J. and Anders, K. and Sidney, J. and Sette, A. and Schumacher, T.N.M. and Keller, C. and Busch, D.H. and Seifert, U. and Blankenstein, T.
Journal of Experimental Medicine 213 (11): 2333-2348. 17 October 2016

Construction of a T cell line-based packaging cell line for the production of T cell receptor retroviruses by enriching of Cd3 expressing cells.
Uckert, W. and Blankenstein, T.
WO0700318. 4 January 2007

Gentherapie mit T-Zellrezeptor modifizierten Zellen.
Uckert, W. and Blankenstein, T.
BioForum 28 (3): 27-30. 20 May 2005

Active MAC-1 (CD11b/CD18) on DC is inhibitory for full T cell activation.
Varga, G. and Balkow, S. and Wild, M.K. and Stadtbaeumer, A. and Krummen, M. and Rothoeft, T. and Higuchi, T. and Beissert, S. and Wethmar, K. and Scharffetter-Kochanek, K. and Vestweber, D. and Grabbe, S.
Blood 109 (2): 661-669. 15 January 2007

HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice.
Vertuani, S. and Triulzi, C. and Roos, A.K. and Charo, J. and Norell, H. and Lemonnier, F. and Pisa, P. and Seliger, B. and Kiessling, R.
Cancer Immunology Immunotherapy 58 (5): 653-664. May 2009

MHCII-independent CD4(+) T cells protect injured CNS neurons via IL-4.
Walsh, J.T. and Hendrix, S. and Boato, F. and Smirnov, I. and Zheng, J. and Lukens, J.R. and Gadani, S. and Hechler, D. and Gölz, G. and Rosenberger, K. and Kammertöns, T. and Vogt, J. and Vogelaar, C. and Siffrin, V. and Radjavi, A. and Fernandez-Castaneda, A. and Gaultier, A. and Gold, R. and Kanneganti, T.D. and Nitsch, R. and Zipp, F. and Kipnis, J.
Journal of Clinical Investigation 125 (2): 699-714. 2 February 2015

Rapid method of total RNA mini-preparation from eucaryotic cells.
Walther, W. and Stein, U. and Uckert, W.
Nucleic Acids Research 21 (7): 1682. 11 April 1993

Dual T cell receptor expressing CD8+ T cells with tumor- and self-specificity can inhibit tumor growth without causing severe autoimmunity.
Weinhold, M. and Sommermeyer, D. and Uckert, W. and Blankenstein, T.
Journal of Immunology 179 (8): 5534-5542. 15 October 2007

Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study.
Westermann, J. and Floercken, A. and Willimsky, G. and van Lessen, A. and Kopp, J. and Takvorian, A. and Joehrens, K. and Lukowsky, A. and Schoenemann, C. and Sawitzki, B. and Pohla, H. and Frank, R. and Doerken, B. and Schendel, D.J. and Blankenstein, T. and Pezzutto, A.
Gene Therapy 18 (4): 354-363. April 2011

Flt-3 ligand as adjuvant for DNA vaccination augments immune responses but does not skew TH1/TH2 polarization.
Westermann, J. and Nguyen-Hoai, T. and Mollweide, A. and Richter, G. and Schmetzer, O. and Kim, H.J. and Blankenstein, T. and Doerken, B. and Pezzutto, A.
Gene Therapy 11 (13): 1048-1056. 1 January 2004

Migration of immature mouse DC across resting endothelium is mediated by ICAM-2 but independent of beta2-integrins and murine DC-SIGN homologues.
Wethmar, K. and Helmus, Y. and Luehn, K. and Jones, C. and Laskowska, A. and Varga, G. and Grabbe, S. and Lyck, R. and Engelhardt, B. and Bixel, M.G. and Butz, S. and Loser, K. and Beissert, S. and Ipe, U. and Vestweber, D. and Wild, M.K.
European Journal of Immunology 36 (10): 2781-2794. October 2006

High salt inhibits tumor growth by enhancing anti-tumor immunity.
Willebrand, R. and Hamad, I. and Van Zeebroeck, L. and Kiss, M. and Bruderek, K. and Geuzens, A. and Swinnen, D. and Côrte-Real, B.F. and Markó, L. and Lebegge, E. and Laoui, D. and Kemna, J. and Kammertoens, T. and Brandau, S. and Van Ginderachter, J.A. and Kleinewietfeld, M.
Frontiers in Immunology 10 : 1141. 4 June 2019

The adaptive immune response to sporadic cancer.
Willimsky, G. and Blankenstein, T.
Immunological Reviews 220 (1): 102-112. December 2007

Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance.
Willimsky, G. and Blankenstein, T.
Nature 437 (7055): 141-146. 1 September 2005

Adoptive T-cell therapy to treat liver cancer: Is the liver microenvironment key?
Willimsky, G. and Protzer, U. and Knolle, P. and Heikenwalder, M.
Oncotarget 4 (8): 1117-1118. August 2013

Virus-induced hepatocellular carcinomas cause antigen-specific local tolerance.
Willimsky, G. and Schmidt, K. and Loddenkemper, C. and Gellermann, J. and Blankenstein, T.
Journal of Clinical Investigation 123 (3): 1032-1043. 1 March 2013

Immunogenicity of premalignant lesions is the primary cause of general cytotoxic T lymphocyte unresponsiveness.
Willimsky, G. and Czeh, M. and Loddenkemper, C. and Gellermann, J. and Schmidt, K. and Wust, P. and Stein, H. and Blankenstein, T.
Journal of Experimental Medicine 205 (7): 1687-1700. 7 July 2008

CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis.
Wolf, S.A. and Steiner, B. and Akpinarli, A. and Kammertoens, T. and Nassenstein, C. and Braun, A. and Blankenstein, T. and Kempermann, G.
Journal of Immunology 182 (7): 3979-3984. 1 April 2009

Adaptive peripheral immune response increases proliferation of neural precursor cells in the adult hippocampus.
Wolf, S.A. and Steiner, B. and Wengner, A.M. and Lipp, M. and Kammertoens, T. and Kempermann, G.
FASEB Journal 23 (9): 3121-3128. September 2009

Long-term suppression of tumor growth by TNF requires a Stat1- and IFN regulatory factor 1-dependent IFN-γ pathway but not IL-12 or IL-18.
Wu, T.H. and Pabin, C.N. and Qin, Z.H. and Blankenstein, T. and Philip, M. and Dignam, J. and Schreiber, K. and Schreiber, H.
Journal of Immunology 172 (5): 3243-3251. 1 January 2004

Fibroblast-specific protein 1/S100A4-positive cells prevent carcinoma through collagen production and encapsulation of carcinogens.
Zhang, J and Chen, L and Liu, X and Kammertoens, T. and Blankenstein, T. and Qin, Z.
Cancer Research 73 (9): 2770-2781. 1 May 2013

Tumor necrosis factor receptor 2-mediated tumor suppression is nitric oxide dependent and involves angiostasis.
Zhao, X. and Mohaupt, M. and Jiang, J. and Liu, S. and Li, B. and Qin, Z.
Cancer Research 67 (9): 4443-4450. 1 May 2007

Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies.
Çakmak-Görür, N. and Radke, J. and Rhein, S. and Schumann, E. and Willimsky, G. and Heppner, F.L. and Blankenstein, T. and Pezzutto, A.
Leukemia 33 (4): 1039-1043. April 2019

Calkhoven, Cornelis F.

Analysis of translation initiation using a translation control reporter system.
Wiesenthal, V. and Leutz, A. and Calkhoven, C.F.
Nature Protocols 1 (3): 1531-1537. 9 November 2006

A translation control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell.
Wiesenthal, V. and Leutz, A. and Calkhoven, C.F.
Nucleic Acids Research 34 (3): e23. 10 February 2006

Cardoso, Cristina

Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.
Gupta, S. and Hoepner, S. and Rupp, B. and Guenther, S. and Dickhaut, K. and Agarwal, N. and Cardoso, M.C. and Kuehne, R. and Wiesmueller, K.H. and Jung, G. and Falk, K. and Roetzschke, O.
PLoS ONE 3 (3): e1814. 19 March 2008

A fraction of MCM 2 proteins remain associated with replication foci during a major part of S phase.
Masata, M. and Juda, P. and Raska, O. and Cardoso, M.C. and Raska, I.
Folia Biologica Prague 57 (1): 3-11. 2011

Chekulaeva, Marina (BIMSB)

Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63 (6): 918-925. 15 September 2016

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. and Rom, A. and Franke, V. and Imami, K. and Arrey, G. and Terne, M. and Woehler, A. and Akalin, A. and Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution.
Mauri, M. and Kirchner, M. and Aharoni, R. and Ciolli Mattioli, C. and van den Bruck, D. and Gutkovitch, N. and Modepalli, V. and Selbach, M. and Moran, Y. and Chekulaeva, M.
Nucleic Acids Research 45 (2): 938-950. 25 January 2017

Translation of circRNAs.
Pamudurti, NR. and Bartok, O. and Jens, M. and Ashwal-Fluss, R. and Stottmeister, C. and Ruhe, L. and Hanan, M. and Wyler, E. and Perez-Hernandez, D. and Ramberger, E. and Shenzis, S. and Samson, M. and Dittmar, G. and Landthaler, M. and Chekulaeva, M. and Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Chen, Wei (BIMSB/BIH)

Identification and functional characterization of hypoxia-induced endoplasmic reticulum stress regulating lncRNA (HypERlnc) in pericytes.
Bischoff, F.C. and Werner, A. and John, D. and Boeckel, J.-N. and Melissari, M.-T. and Grote, P. and Glaser, S.F. and Demolli, S. and Uchida, S. and Michalik, K.M. and Meder, B. and Katus, H.A. and Haas, J. and Chen, W. and Pullamsetti, S.S. and Seeger, W. and Zeiher, A.M. and Dimmeler, S. and Zehendner, C.M.
Circulation Research 121 (4): 368-375. 4 August 2017

Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N. and Perret, M.F. and Glaser, S.F. and Seeger, T. and Heumüller, A.W. and Chen, W. and John, D. and Kokot, K.E. and Katus, H.A. and Haas, J. and Lackner, M.K. and Kayvanpour, E. and Grabe, N. and Dieterich, C. and von Haehling, S. and Ebner, N. and Hünecke, S. and Leuschner, F. and Fichtlscherer, S. and Meder, B. and Zeiher, A.M. and Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126 : 13-22. January 2019

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B. and Eichelbaum, K. and Sadewasser, A. and Wang, X. and Husic, I. and Paki, K. and Hergeselle, M. and Vetter, B. and Hou, J. and Chen, W. and Wiebusch, L. and Meyer, I.M. and Wolff, T. and Selbach, M.
bioRxiv : 438176. 8 October 2018

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Buonocore, F. and Kuehnen, P. and Suntharalingham, J.P. and Del Valle, I. and Digweed, M. and Stachelscheid, H. and Khajavi, N. and Didi, M. and Brady, A.F. and Blankenstein, O. and Procter, A.M. and Dimitri, P. and Wales, J.K.H. and Ghirri, P. and Knoebl, D. and Strahm, B. and Erlacher, M. and Wlodarski, M.W. and Chen, W. and Kokai, G.K. and Anderson, G. and Morrogh, D. and Moulding, D.A. and McKee, S. A. and Niemeyer, C.M. and Grueters, A. and Achermann, J.C.
Journal of Clinical Investigation 127 (5): 1700-1713. 1 May 2017

Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.
Cui, H. and Bansal, V. and Grunert, M. and Malecova, B. and Dall Agnese, A. and Latella, L. and Gatto, S. and Ryan, T. and Schulz, K. and Chen, W. and Dorn, C. and Puri, P.L. and Sperling, S.R.
PLoS ONE 12 (6): e0179464. 13 June 2017

Epigenomic profiling of human CD4(+) T cells supports a linear differentiation model and highlights molecular regulators of memory development.
Durek, P. and Nordström, K. and Gasparoni, G. and Salhab, A. and Kressler, C. and de Almeida, M. and Bassler, K. and Ulas, T. and Schmidt, F. and Xiong, J. and Glažar, P. and Klironomos, F. and Sinha, A. and Kinkley, S. and Yang, X. and Arrigoni, L. and Amirabad, A.. and Ardakani, F.B. and Feuerbach, L. and Gorka, O. and Ebert, P. and Müller, F. and Li, N. and Frischbutter, S. and Schlickeiser, S. and Cendon, C. and Fröhler, S. and Felder, B. and Gasparoni, N. and Imbusch, C.D. and Hutter, B. and Zipprich, G. and Tauchmann, Y. and Reinke, S. and Wassilew, G. and Hoffmann, U. and Richter, A.S. and Sieverling, L. and Chang, H.D. and Syrbe, U. and Kalus, U. and Eils, J. and Brors, B. and Manke, T. and Ruland, J. and Lengauer, T. and Rajewsky, N. and Chen, W. and Dong, J. and Sawitzki, B. and Chung, H.R. and Rosenstiel, P. and Schulz, M.H. and Schultze, J.L. and Radbruch, A. and Walter, J. and Hamann, A. and Polansky, J.K.
Immunity 45 (5): 1148-1161. 15 November 2016

Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells.
Gogol-Döring, A. and Ammar, I. and Gupta, S. and Bunse, M. and Miskey, C. and Chen, W. and Uckert, W. and Schulz, T.F. and Izsvák, Z. and Ivics, Z.
Molecular Therapy 24 (3): 592-606. March 2016

Genetics of intellectual disability in consanguineous families.
Hu, H. and Kahrizi, K. and Musante, L. and Fattahi, Z. and Herwig, R. and Hosseini, M. and Oppitz, C. and Abedini, S.S. and Suckow, V. and Larti, F. and Beheshtian, M. and Lipkowitz, B. and Akhtarkhavari, T. and Mehvari, S. and Otto, S. and Mohseni, M. and Arzhangi, S. and Jamali, P. and Mojahedi, F. and Taghdiri, M. and Papari, E. and Soltani Banavandi, M.J. and Akbari, S. and Tonekaboni, S.H. and Dehghani, H. and Ebrahimpour, M.R. and Bader, I. and Davarnia, B. and Cohen, M. and Khodaei, H. and Albrecht, B. and Azimi, S. and Zirn, B. and Bastami, M. and Wieczorek, D. and Bahrami, G. and Keleman, K. and Vahid, L.N. and Tzschach, A. and Gärtner, J. and Gillessen-Kaesbach, G. and Varaghchi, J.R. and Timmermann, B. and Pourfatemi, F. and Jankhah, A. and Chen, W. and Nikuei, P. and Kalscheuer, V.M. and Oladnabi, M. and Wienker, T.F. and Ropers, H.H. and Najmabadi, H.
Molecular Psychiatry 24 (7): 1027-1039. July 2019

Long noncoding RNA lISPR1 is required for S1P signaling and endothelial cell function.
Josipovic, I. and Pflueger, B. and Fork, C. and Vasconez, A.E. and Oo, J.A. and Hitzel, J. and Seredinski, S. and Gamen, E. and Heringdorf, D.M.Z. and Chen, W. and Looso, M. and Pullamsetti, S.S. and Brandes, R.P. and Leisegang, M.S.
Journal of Molecular and Cellular Cardiology 116 : 57-68. March 2018

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M. and Perrod, C. and Hoogenkamp, M. and Ghani, S. and Assi, S. and Heinz, S. and Wilson, N.K. and Follows, G. and Schoenheit, J. and Vockentanz, L. and Mosamam, A. and Chen, W. and Tenen, D.G. and Westhead, D.R. and Goettgens, B. and Bonifer, C. and Rosenbauer, F.
Blood 117 (10): 2827-2838. 10 March 2011

The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.
Leisegang, M.S. and Gu, L. and Preussner, J. and Günther, S. and Hitzel, J. and Ratiu, C. and Weigert, A. and Chen, W. and Schwarz, E.C. and Looso, M. and Fork, C. and Brandes, R.P.
FEBS Letters 593 (5): 487-498. March 2019

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.
Löber, U. and Hobbs, M. and Dayaram, A. and Tsangaras, K. and Jones, K. and Alquezar-Planas, D.E. and Ishida, Y. and Meers, J. and Mayer, J. and Quedenau, C. and Chen, W. and Johnson, R.N. and Timms, P. and Young, P.R. and Roca, A.L. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): 8609-8614. 21 August 2018

An integrated understanding of the molecular mechanisms how adipose tissue metabolism affects long-term body weight maintenance.
Mai, K. and Li, L. and Wiegand, S. and Brachs, M. and Leupelt, V. and Ernert, A. and Kühnen, P. and Hübner, N. and Robinson, P. and Chen, W. and Krude, H. and Spranger, J.
Diabetes 68 (1): 57-65. 1 January 2019

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N. and Kolesnichenko, M. and Beaudette, P. and Popp, O. and Uyar, B. and Sun, W. and Tufan, A.B. and Perder, B. and Akalin, A. and Chen, W. and Mertins, P. and Dittmar, G. and Hinz, M. and Scheidereit, C.
EMBO Journal 37 (24): e98658. 14 December 2018

Identification of the elementary structural units of the DNA damage response.
Natale, F. and Rapp, A. and Yu, W. and Maiser, A. and Harz, H. and Scholl, A. and Grulich, S. and Anton, T. and Hoerl, D. and Chen, W. and Durante, M. and Taucher-Scholz, G. and Leonhardt, H. and Cardoso, M.C.
Nature Communications 8 : 15760. 12 June 2017

Pontine tegmental cap dysplasia in an extremely preterm infant and review of the literature.
Picker-Minh, S. and Hartenstein, S. and Proquitte, H. and Froehler, S. and Raile, V. and Kraemer, N. and Apeshiotis, S. and Leipoldt, M. and Kalache, K.D. and Morris-Rosendahl, D. and Boltshauser, E. and Chen, W. and Kaindl, A.M.
Journal of Child Neurology 32 (3): 334-340. March 2017

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt, F. and Gasparoni, N. and Gasparoni, G. and Gianmoena, K. and Cadenas, C. and Polansky, J.K. and Ebert, P. and Nordstroem, K. and Barann, M. and Sinha, A. and Froehler, S. and Xiong, J. and Amirabad, A.D. and Ardakani, F.B. and Hutter, B. and Zipprich, G. and Felder, B. and Eils, J. and Brors, B. and Chen, W. and Hengstler, J.G. and Hamann, A. and Lengauer, T. and Rosenstiel, P. and Walter, J. and Schulz, M.H.
bioRxiv : 081935. 19 October 2016

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt, F. and Gasparoni, N. and Gasparoni, G. and Gianmoena, K. and Cadenas, C. and Polansky, J.K. and Ebert, P. and Nordstroem, K. and Barann, M. and Sinha, A. and Froehler, S. and Xiong, J. and Dehghani Amirabad, A. and Behjati Ardakani, F. and Hutter, B. and Zipprich, G. and Felder, B. and Eils, J. and Brors, B. and Chen, W. and Hengstler, J.G. and Hamann, A. and Lengauer, T. and Rosenstiel, P. and Walter, J. and Schulz, M.H.
Nucleic Acids Research 45 (1): 54-66. 9 January 2017

Comprehensive small RNA-Seq of adeno-associated virus (AAV)-infected human cells detects patterns of novel, non-coding AAV RNAs in the absence of cellular miRNA regulation.
Stutika, C. and Mietzsch, M. and Gogol-Doering, A. and Weger, S. and Sohn, M. and Chen, W. and Heilbronn, R.
PLoS ONE 11 (9): e0161454. 9 September 2016

Metabolic labeling of newly synthesized RNA with 4sU to in parallel assess RNA transcription and decay.
Sun, W. and Chen, W.
Methods in Molecular Biology 1720 : 25-34. 2018

Pervasive allele-specific regulation on RNA decay in hybrid mice.
Sun, W. and Gao, Q. and Schaefke, B. and Hu, Y. and Chen, W.
Life Science Alliance 1 (2): e201800052. May 2018

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. and Xie, G. and Singh, M. and Ghanbarian, A.T. and Raskó, T. and Szvetnik, A. and Cai, H. and Besser, D. and Prigione, A. and Fuchs, N.V. and Schumann, G.G. and Chen, W. and Lorincz, M.C. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Splicing factor Rbm10 facilitates heterochromatin assembly in fission yeast.
Weigt, M. and Gao, Q. and Ban, H. and He, H. and Mastrobuoni, G. and Kempa, S. and Chen, W. and Li, F.
bioRxiv : 518936. 11 January 2019

Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation.
Xiao, M.S. and Zhang, B. and Li, Y.S. and Gao, Q. and Sun, W. and Chen, W.
Molecular Systems Biology 12 (12): 890. 8 December 2016

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
Yang, J.Y. and Deng, X.Y. and Li, Y.S. and Ma, X.C. and Feng, J.X. and Yu, B. and Chen, Y. and Luo, Y.L. and Wang, X. and Chen, M.L. and Fang, Z.X. and Zheng, F.X. and Li, Y.P. and Zhong, Q. and Kang, T.B. and Song, L.B. and Xu, R.H. and Zeng, M.S. and Chen, W. and Zhang, H. and Xie, W. and Gao, S.
Nature Communications 9 (1): 1165. 21 March 2018

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression.
Zhang, B. and Calado, D.P. and Wang, Z. and Froehler, S. and Koechert, K. and Qian, Y. and Koralov, S.B. and Schmidt-Supprian, M. and Sasaki, Y. and Unitt, C. and Rodig, S. and Chen, W. and Dalla-Favera, R. and Alt, F.W. and Pasqualucci, L. and Rajewsky, K.
Cell Reports 11 (5): 715-726. 5 May 2015

Damaschun, Gregor

Multimodal particle size distribution or fractal surface of acrylic acid copolymer nanoparticles: A small-angle X-ray scattering study using direct Fourier and indirect maximum entropy methods.
Mueller, J.J. and Hansen, S. and Lukowski, G. and Gast, K.
Journal of Applied Crystallography 28 (Pt 6): 774-781. 1 December 1995

AKIMA interpolation: A tool used in direct slit-length desmearing procedures of non-frequency- limited X-ray scattering curves.
Mueller, J.J. and Mueller, E.C. and Gernat, C. and Kroeber, R.
Journal of Applied Crystallography 28 (Pt 1): 38-42. 1 February 1995

Daniel, Peter

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K. and Buschow, C. and Herrmann, A. and Milojkovic, A. and Loddenkemper, C. and Kammertoens, T. and Daniel, P. and Yu, H. and Charo, J. and Blankenstein, T.
Cancer Cell 20 (6): 755-767. 13 December 2011

Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Arnold, W. and Daniel, P.T. and Mapara, M.Y. and Grinstein, E. and Royer, H.D. and Doerken, B.
Journal of Experimental Medicine 183 (3): 1205-1213. 1 March 1996

Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Mapara, M.Y. and Daniel, P.T. and Arnold, W. and Dietel, M. and Guski, H. and Feller, A. and Royer, H.D. and Doerken, B.
Journal of Clinical Investigation 97 (11): 2651-2659. 1 June 1996

DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis.
Bhonde, M.R. and Hanski, M.L. and Budczies, J. and Cao, M. and Gillissen, B. and Moorthy, D. and Simonetta, F. and Scheruebl, H. and Truss, M. and Hagemeier, C. and Mewes, H.W. and Daniel, P.T. and Zeitz, M. and Hanski, C.
Journal of Biological Chemistry 281 : 8675-8685. 31 March 2006

The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein.
Bhonde, M.R. and Hanski, M.L. and Magrini, R. and Moorthy, D. and Mueller, A. and Sausville, E.A. and Kohno, K. and Wiegand, P. and Daniel, P.T. and Zeitz, M. and Hanski, C.
Oncogene 24 : 148-156. 6 January 2005

Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.
Bhonde, M.R. and Hanski, M.L. and Notter, M. and Gillissen, B.F. and Daniel, P.T. and Zeitz, M. and Hanski, C.
Oncogene 25 : 165-175. 12 January 2006

Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia.
Bosanquet, A.G. and Sturm, I. and Wieder, T. and Essmann, F. and Bosanquet, M.I. and Head, F.J. and Doerken, B. and Daniel, P.T.
Leukemia 16 (6): 1035-1044. June 2002

Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.
Burek, M. and Maddika, S. and Burek, C.J. and Daniel, P.T. and Schulze-Osthoff, K. and Los, M.
Oncogene 25 : 2213-2222. 6 April 2006

Bax-dependent regulation of Bak by voltage-dependent anion channel 2.
Chandra, D. and Choy, G. and Daniel, P.T. and Tang, D.G.
Journal of Biological Chemistry 280 : 19051-19061. 1 January 2005

Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death.
Chandra, D. and Choy, G. and Deng, X. and Bhatia, B. and Daniel, P. and Tang, D.G.
Molecular and Cellular Biology 24 : 6592-6607. 1 January 2004

Immediate effects of reversible HTLV-I tax function: T-cell activation and apoptosis.
Chlichlia, K. and Moldenhauer, G. and Daniel, P.T. and Busslinger, M. and Gazzalo, L. and Schirrmacher, V. and Khazaie, K.
Oncogene 10 (2): 269-277. 19 January 1995

Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
Chumduri, C. and Gillissen, B. and Richter, A. and Richter, A. and Milojkovic, A. and Overkamp, T. and Mueller, A. and Pott, C. and Daniel, P.T.
Journal of Molecular Medicine 93 (5): 559-572. May 2015

Molekulare Grundlagen der zielgerichteten Tumortherapie [The molecular bases of targeted tumor therapy].
Daniel, P.
Onkologe 13 (1): 8-19. January 2007

Zellzyklus und Apoptose.
Daniel, P.T.
In: Molekularmedizinische Grundlagen von haematologischen Neoplasien. Molekulare Medizin . Springer, Berlin [u.a.], 130-184. ISBN 3-540-41640-4 1 January 2003

Grundlagen der molekularen Diagnostik und Therapie maligner Tumoren [Basics of molecular diagnostics and therapy of malignant tumors].
Daniel, P.T. and Doerken, B.
Internist 46 (8): 835-846. 12 July 2005

Apoptolidin: Induction of apoptosis by a natural product.
Daniel, P.T. and Koert, U. and Schuppan, J.
Angewandte Chemie International Edition 45 : 872-893. 30 January 2006

Guardians of cell death: the Bcl-2 family proteins.
Daniel, P.T. and Schulze-Osthoff, K. and Belka, C. and Guener, D.
Essays in Biochemistry 39 : 73-88. 1 October 2003

Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T. and Kroidl, A. and Kopp, J. and Sturm, I. and Moldenhauer, G. and Doerken, B. and Pezzutto, A.
Blood 92 (12): 4750-4757. 15 December 1998

Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.
Daniel, P.T. and Kroidl, A. and Cayeux, S. and Bargou, R.C. and Blankenstein, T. and Doerken, B.
Journal of Immunology 159 (8): 3808-3815. 15 October 1997

Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference.
Denkert, C. and Fuerstenberg, A. and Daniel, P.T. and Koch, I. and Koebel, M. and Weichert, W. and Siegert, A. and Hauptmann, S.
Oncogene 22 (54): 8653-8661. 27 November 2003

CD95/Fas signaling in human melanoma cells: conditional expression of CD95L/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants.
Eberle, J. and Fecker, L.F. and Hossini, A.M. and Wieder, T. and Daniel, P.T. and Orfanos, C.E. and Geilen, C.C.
Oncogene 22 (57): 9131-9141. 11 December 2003

Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak and augments drug response.
Einsele-Scholz, S. and Malmsheimer, S. and Bertram, K. and Stehle, D. and Johaenning, J. and Manz, M. and Daniel, P.T. and Gillissen, B.F. and Schulze-Osthoff, K. and Essmann, F.
Journal of Cell Science 129 (11): 2213-2223. 1 June 2016

Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis.
Essmann, F. and Pohlmann, S. and Gillissen, B. and Daniel, P.T. and Schulze-Osthoff, K. and Jaenicke, R.U.
Journal of Biological Chemistry 280 (44): 37169-37177. 4 November 2005

Loss of proapoptotic Bcl-2-related multidomain proteins in primary melanomas is associated with poor prognosis.
Fecker, L.F. and Geilen, C.C. and Tchernev, G. and Trefzer, U. and Assaf, C. and Kurbanov, B.M. and Schwarz, C. and Daniel, P.T. and Eberle, J.
Journal of Investigative Dermatology 126 : 1366-1371. June 2006

Cellular fingerprints: a novel approach using large-scale cancer cell line data for the identification of potential anticancer agents.
Fuellbeck, M. and Dunkel, M. and Hossbach, J. and Daniel, P.T. and Preissner, R.
Chemical Biology & Drug Design 74 (5): 439-448. November 2009

Computer-assisted identification of small-molecule Bcl-2 modulators.
Fuellbeck, M. and Gebhardt, N. and Hossbach, J. and Daniel, P.T. and Preissner, R.
Computational Biology and Chemistry 33 (6): 451-456. December 2009

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
Gillissen, B. and Essmann, F. and Graupner, V. and Staerck, L. and Radetzki, S. and Doerken, B. and Schulze-Osthoff, K. and Daniel, P.T.
EMBO Journal 22 (14): 3580-3590. 15 July 2003

Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
Gillissen, B. and Essmann, F. and Hemmati, P.G. and Richter, A. and Richter, A. and Oztop, I. and Chinnadurai, G. and Doerken, B. and Daniel, P.T.
Journal of Cell Biology 179 (4): 701-715. 19 November 2007

Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode.
Gillissen, B. and Richter, A. and Richter, A. and Overkamp, T. and Essmann, F. and Hemmati, P.G. and Preissner, R. and Belka, C. and Daniel, P.T.
Cell Death & Disease 4 : e643. 23 May 2013

Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B. and Richter, A. and Richter, A. and Preissner, R. and Schulze-Osthoff, K. and Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292 (16): 6478-6492. 21 April 2017

Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.
Gillissen, B. and Wendt, J. and Richter, A. and Richter, A. and Mueer, A. and Overkamp, T. and Gebhardt, N. and Preissner, R. and Belka, C. and Doerken, B. and Daniel, P.T.
Journal of Cell Biology 188 (6): 851-862. 22 March 2010

2D and 3D similarity landscape analysis identifies PARP as a novel off-target for the drug Vatalanib.
Gohlke, B.O. and Overkamp, T. and Richter, A. and Richter, A. and Daniel, P.T. and Gillissen, B. and Preissner, R.
BMC Bioinformatics 16 (1): 308. 24 September 2015

Analysis of neuroendocrine differentiation and the p53/BAX pathway in UICC stage III colorectal carcinoma identifies patients with good prognosis.
Grabowski, P. and Sturm, I. and Schelwies, K. and Maaser, K. and Buhr, H.J. and Doerken, B. and Zeitz, M. and Daniel, P.T. and Scheruebl, H.
International Journal of Colorectal Disease 21 : 221-230. April 2006

Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level.
Graupner, V. and Alexander, E. and Overkamp, T. and Rothfuss, O. and De Laurenzi, V. and Gillissen, B.F. and Daniel, P.T. and Schulze-Osthoff, K. and Essmann, F.
Cell Death and Differentiation 18 (7): 1130-1139. July 2011

Disruption of cell death signaling in cancer: impact on disease prognosis and response to therapy.
Guener, D. and Belka, C. and Daniel, P.T.
Current Medicinal Chemistry Anti-Cancer Agents 3 (5): 319-326. 1 September 2003

Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.
Guener, D. and Sturm, I. and Hemmati, P. and Hermann, S. and Hauptmann, S. and Wurm, R. and Budach, V. and Doerken, B. and Lorenz, M. and Daniel, P.T.
International Journal of Cancer 103 (4): 445-454. 10 February 2003

Deregulation von Zellzyklus und Apoptose beim Plattenepithelkarzinom des Oesophagus.
Guener, D.
UNSPECIFIED thesis, UNSPECIFIED. 30 September 2003

Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway.
Habermehl, D. and Kammerer, B. and Handrick, R. and Eldh, T. and Gruber, C. and Cordes, N. and Daniel, P.T. and Plasswilm, L. and Bamberg, M. and Belka, C. and Jendrossek, V.
BMC Cancer 6 : 14. 17 January 2006

Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax.
Handrick, R. and Ganswindt, U. and Faltin, H. and Goecke, B. and Daniel, P.T. and Budach, W. and Belka, C. and Jendrossek, V.
Radiotherapy and Oncology 90 (3): 413-421. March 2009

Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-xL in a strictly caspase-3-dependent manner in human carcinoma cells.
Hasenjaeger, A. and Gillissen, B. and Mueller, A. and Normand, G. and Hemmati, P.G. and Schuler, M. and Doerken, B. and Daniel, P.T.
Oncogene 23 (26): 4523-4535. 3 June 2004

Bak functionally complements for loss of Bax during p14(ARF)-induced mitochondrial apoptosis in human cancer cells.
Hemmati, P.G. and Guener, D. and Gillissen, B. and Wendt, J. and von Haefen, C. and Chinnadurai, G. and Doerken, B. and Daniel, P.T.
Oncogene 25 (50): 6582-6594. 26 October 2006

Systematic genetic dissection of p14(ARF)-mediated mitochondrial cell death signaling reveals a key role for p21(CDKN1) and the BH3-only protein Puma/bbc3.
Hemmati, P.G. and Mueer, A. and Gillissen, B. and Overkamp, T. and Milojkovic, A. and Wendt, J. and Doerken, B. and Daniel, P.T.
Journal of Molecular Medicine 88 (6): 609-622. June 2010

Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.
Hemmati, P.G. and Normand, G. and Gillissen, B. and Wendt, J. and Doerken, B. and Daniel, P.T.
Oncogene 27 (53): 6707-6719. 4 December 2008

Loss of p21 disrupts p14ARF-induced G1 cell cycle arrest but augments p14ARF-induced apoptosis in human carcinoma cells.
Hemmati, P.G. and Normand, G. and Verdoodt, B. and von Haefen, C. and Hasenjaeger, A. and Guener, D. and Wendt, J. and Doerken, B. and Daniel, P.T.
Oncogene 24 (25): 4114-4128. 1 January 2005

Adenovirus-mediated overexpression of p14ARF induces p53 and Bax-independent apoptosis.
Hemmati, P.G. and Gillissen, B. and von Haefen, C. and Wendt, J. and Staerck, L. and Guener, D. and Doerken, B. and Daniel, P.T.
Oncogene 21 (20): 3149-3161. 9 May 2002

Assessment of free light chains in the cerebrospinal fluid of patients with lymphomatous meningitis - a pilot study.
Hildebrandt, B. and Mueller, C. and Pezzutto, A. and Daniel, P.T. and Doerken, B. and Scholz, C.
BMC Cancer 7 : 185. 3 October 2007

Inhibiting the inhibitors: retro-inverso Smac peptides.
Hossbach, J. and Michalsky, E. and Henklein, P. and Jaeger, M. and Daniel, P.T. and Preissner, R.
Peptides 30 (12): 2374-2379. December 2009

A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain.
Hossini, A.M. and Geilen, C.C. and Fecker, L.F. and Daniel, P.T. and Eberle, J.
Oncogene 25 : 2160-2169. 6 April 2006

Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway.
Hu, H. and Jiang, C. and Schuster, T. and Li, G.X. and Daniel, P.T. and Lue, J.
Molecular Cancer Therapeutics 5 : 1873-1882. July 2006

Inhibition of the ER Ca2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis.
Janssen, K. and Horn, S. and Niemann, M.T. and Daniel, P.T. and Schulze-Osthoff, K. and Fischer, U.
Journal of Cell Science 122 (Pt 24): 4481-4491. 15 December 2009

Long-term follow-up of patients with Philadelphia chromosome-positive chronic myeloid leukemia after stem cell mobilization under imatinib.
Kim, T.D. and Schwarz, M. and Kreuzer, K.A. and Kaeda, J. and Movassaghi, K. and Grille, P. and Daniel, P.T. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 52 (3): 517-520. March 2011

Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D. and Tuerkmen, S. and Schwarz, M. and Koca, G. and Nogai, H. and Bommer, C. and Doerken, B. and Daniel, P. and le Coutre, P.
Haematologica 95 (4): 582-588. April 2010

Adenine deoxynucleotides fludarabine and cladribine induce apoptosis in a CD95/Fas receptor, FADD and caspase-8-independent manner by activation of the mitochondrial cell death pathway.
Kloepfer, A. and Hasenjaeger, A. and Belka, C. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 23 : 9408-9418. 1 January 2004

Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule.
Lagresle, C. and Bella, C. and Daniel, P.T. and Krammer, P.H. and Defrance, T.
Journal of Immunology 154 (11): 5746-5756. 1 June 1995

Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
Li, M. and Jung, A. and Ganswindt, U. and Marini, P. and Friedl, A. and Daniel, P.T. and Lauber, K. and Jendrossek, V. and Belka, C.
Biochemical Pharmacology 79 (2): 122-129. 15 January 2010

Involvement of NAK-1, the human nur77 homologue, in surface IgM-mediated apoptosis in Burkitt lymphoma cell line BL41.
Mapara, M.Y. and Weinmann, P. and Bommert, K. and Daniel, P.T. and Bargou, R.C. and Doerken, B.
European Journal of Immunology 25 (9): 2506-2510. September 1995

Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo.
Marini, P. and Denzinger, S. and Schiller, D. and Kauder, S. and Welz, S. and Humphreys, R. and Daniel, P.T. and Jendrossek, V. and Budach, W. and Belka, C.
Oncogene 25 : 5145-5154. 24 August 2006

Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis.
Marini, P. and Schmid, A. and Jendrossek, V. and Faltin, H. and Daniel, P.T. and Budach, W. and Belka, C.
BMC Cancer 5 : 5. 14 January 2005

p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.
Milojkovic, A. and Hemmati, P.G. and Mueer, A. and Overkamp, T. and Chumduri, C. and Jaenicke, R.U. and Gillissen, B. and Daniel, P.T.
International Journal of Cancer 133 (11): 2551-2562. 1 December 2013

Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability.
Mrozek, A. and Petrowsky, H. and Sturm, I. and Kraus, J. and Hermann, S. and Hauptmann, S. and Lorenz, M. and Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 10 (4): 461-467. 1 April 2003

Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma.
Mueller, A. and Zang, C. and Chumduri, C. and Doerken, B. and Daniel, P.T. and Scholz, C.W.
International Journal of Cancer 133 (8): 1813-1824. 15 October 2013

p14ARF-induced apoptosis in p53-deficient cells is mediated by the BH3-only protein independent de-repression of Bak through down-regulation of Mcl-1 and Bcl-xL.
Muer, A. and Overkamp, T. and Gillissen, B. and Richter, A. and Pretzsch, T. and Milojkovic, A. and Doerken, B. and Daniel, P.T. and Hemmati, P.
Journal of Biological Chemistry 287 (21): 17343-17352. 18 May 2012

Pan-class I  PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.
Müller, A. and Gillissen, B. and Richter, A. and Richter, A. and Chumduri, C. and Daniel, P.T. and Scholz, C.W.
Cell Death & Disease 9 (3): 384. 7 March 2018

Adenoviral natural born killer gene therapy for malignant glioma.
Naumann, U. and Schmidt, F. and Wick, W. and Frank, B. and Weit, S. and Gillissen, B. and Daniel, P. and Weller, M.
Human Gene Therapy 14 (13): 1235-1246. 1 September 2003

Efficacy of triple therapies including ionising radiation, agonistic TRAIL antibodies and cisplatin.
Niyazi, M. and Marini, P. and Daniel, P.T. and Humphreys, R. and Jendrossek, V. and Belka, C.
Oncology Reports 21 (6): 1455-1460. June 2009

Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Niyazi, M. and Marini, P. and Daniel, P.T. and Humphreys, R. and Jendrossek, V. and Belka, C.
Strahlentherapie und Onkologie 185 (1): 8-18. January 2009

p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity.
Normand, G. and Hemmati, P.G. and Verdoodt, B. and von Haefen, C. and Wendt, J. and Guener, D. and May, E. and Doerken, B. and Daniel, P.T.
Journal of Biological Chemistry 280 : 7118-7130. 1 January 2005

Sequencing of NUMB transcripts in chronic myeloid leukaemia detects two single nucleotide polymorphisms.
Oberender, C. and Kaeda, J. and Pawlaczyk-Peter, B. and Daniel, P. and Arnold, R. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 54 (2): 421-422. February 2013

Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk/Bik.
Oppermann, M. and Geilen, C.C. and Fecker, L.F. and Gillissen, B. and Daniel, P.T. and Eberle, J.
Oncogene 24 : 7369-7380. 4 July 2005

Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells.
Ploetz, M. and Gillissen, B. and Hossini, A.M. and Daniel, P.T. and Eberle, J.
Cell Death and Differentiation 19 (12): 1928-1938. December 2012

The BH3-only protein Bim(L) overrides Bcl-2-mediated apoptosis resistance in melanoma cells.
Ploetz, M. and Gillissen, B. and Quast, S.A. and Berger, A. and Daniel, P.T. and Eberle, J.
Cancer Letters 335 (1): 100-108. 10 July 2013

Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK).
Ploetz, M. and Hossini, A.M. and Gillissen, B. and Daniel, P.T. and Stockfleth, E. and Eberle, J.
PLoS ONE 7 (4): e34549. 10 April 2012

Induction of apoptosis by enediyne antibiotic calicheamicin gammaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner.
Prokop, A. and Wrasidlo, W. and Lode, H. and Herold, R. and Lang, F. and Henze, G. and Doerken, B. and Wieder, T. and Daniel, P.T.
Oncogene 22 (57): 9107-9120. 11 December 2003

The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines.
Radetzki, S. and Koehne, C.H. and von Haefen, C. and Gillissen, B. and Sturm, I. and Doerken, B. and Daniel, P.T.
Oncogene 21 (2): 227-238. 10 January 2002

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.
Radhakrishnan, H. and Ilm, K. and Walther, W. and Shirasawa, S. and Sasazuki, T. and Daniel, P.T. and Gillissen, B. and Stein, U.
Cancer Letters 403 : 231-245. 10 September 2017

Dynamic expression profile of p21 WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy.
Rau, B. and Sturm, I. and Lage, H. and Berger, S. and Schneider, U. and Haupfmann, S. and Wust, P. and Riess, H. and Schlag, P.M. and Doerken, B. and Daniel, P.T.
Journal of Clinical Oncology 21 (18): 3391-3401. 15 September 2003

Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker.
Reimer, T.A. and Anagnostopoulos, I. and Erdmann, B. and Lehmann, I. and Stein, H. and Daniel, P. and Doerken, B. and Rehm, A.
BMC Cancer 5 (1): 47. 1 January 2005

Type I and type II reactions in TRAIL-induced apoptosis - results from dose-response studies.
Rudner, J. and Jendrossek, V. and Lauber, K. and Daniel, P.T. and Wesselborg, S. and Belka, C.
Oncogene 24 : 130-140. 6 January 2005

Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors.
Schelwies, K. and Sturm, I. and Grabowski, P. and Scherubl, H. and Schindler, I. and Hermann, S. and Stein, H. and Buhr, H.J. and Riecken, E.O. and Zeitz, M. and Doerken, B. and Daniel, P.T.
International Journal of Cancer 99 (4): 589-596. 1 June 2002

Tumor necrosis factor α sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-κB.
Schmelz, K. and Wieder, T. and Tamm, I. and Mueller, A. and Essmann, F. and Geilen, C.C. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 23 (40): 6743-6759. 2 September 2004

Dysferlin-peptides reallocate mutated dysferlin thereby restoring function.
Schoewel, V. and Marg, A. and Kunz, S. and Overkamp, T. and Siegert Carrazedo, R. and Zacharias, U. and Daniel, P.T. and Spuler, S.
PLoS ONE 7 (11): e49603. 20 November 2012

Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway.
Scholz, C. and Richter, A. and Lehmann, M. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 24 (47): 7031-7042. 27 October 2005

Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.
Scholz, C. and Wieder, T. and Staerck, L. and Essmann, F. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 24 : 1904-1913. 1 January 2005

Necrotic death but not irradiation abolishes costimulation of T-cell effector functions and survival by CD80-expressing tumor cells.
Staerck, L. and Scholz, C. and Blankenstein, T. and Doerken, B. and Daniel, P.T.
International Journal of Cancer 116 (1): 78-86. 1 January 2005

Costimulation by CD137/4-1BB inhibits T cell apoptosis and induces Bcl-xL and c-FLIPshort via phosphatidylinositol 3-kinase and AKT/protein kinase B.
Staerck, L. and Scholz, C. and Doerken, B. and Daniel, P.T.
European Journal of Immunology 35 : 1257-1266. 1 January 2005

Non-genotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.
Stuehmer, T. and Chatterjee, M. and Hildebrandt, M. and Herrmann, P. and Gollasch, H. and Gerecke, C. and Theurich, S. and Cigliano, L. and Manz, R.A. and Daniel, P.T. and Bommert, K. and Vassilev, L.T. and Bargou, R.C.
Blood 106 : 3609-3617. 4 August 2005

Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy.
Sturm, I. and Bosanquet, A.G. and Hermann, S. and Guener, D. and Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 10 (4): 477-484. 1 April 2003

In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis.
Sturm, I. and Bosanquet, A.G. and Hummel, M. and Doerken, B. and Daniel, P.T.
BMC Cancer 5 : 105. 18 August 2005

Silencing of APAF-1 in B-CLL results in poor prognosis in the case of concomitant p53 mutation.
Sturm, I. and Bosanquet, A.G. and Radetzki, S. and Hummel, M. and Doerken, B. and Daniel, P.T.
International Journal of Cancer 118 : 2329-2336. 1 May 2006

Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy.
Sturm, I. and Rau, B. and Schlag, P.M. and Wust, P. and Hildebrandt, B. and Riess, H. and Hauptmann, S. and Doerken, B. and Daniel, P.T.
BMC Cancer 6 : 124. 10 May 2006

Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Sturm, I. and Stephan, C. and Gillissen, B. and Siebert, R. and Janz, M. and Radetzki, S. and Jung, K. and Loening, S. and Doerken, B. and Daniel, P.T.
Cell Death and Differentiation 13 : 619-627. April 2006

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes.
Volcic, M. and Karl, S. and Baumann, B. and Salles, D. and Daniel, P. and Fulda, S. and Wiesmueller, L.
Nucleic Acids Research 40 (1): 181-195. January 2012

Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells.
Wendt, J. and Radetzki, S. and von Haefen, C. and Hemmati, P.G. and Guener, D. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 25 : 972-980. 16 February 2006

TRAIL sensitizes for ionizing irradiation-induced apoptosis through an entirely Bax-dependent mitochondrial cell death pathway.
Wendt, J. and von Haefen, C. and Hemmati, P. and Belka, C. and Doerken, B. and Daniel, P.T.
Oncogene 24 (25): 4052-4064. 1 January 2005

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.
Zaltsman, Y. and Shachnai, L. and Yivgi-Ohana, N. and Schwarz, M. and Maryanovich, M. and Houtkooper, R.H. and Vaz, F.M. and De Leonardis, F. and Fiermonte, G. and Palmieri, F. and Gillissen, B. and Daniel, P.T. and Jimenez, E. and Walsh, S. and Koehler, C.M. and Roy, S.S. and Walter, L. and Hajnoczky, G. and Gross, A.
Nature Cell Biology 12 (6): 553-562. June 2010

Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.
Zantl, N. and Weirich, G. and Zall, H. and Seiffert, B.M. and Fischer, S.F. and Kirschnek, S. and Hartmann, C. and Fritsch, R.M. and Gillissen, B. and Daniel, P.T. and Haecker, G.
Oncogene 26 (49): 7038-7048. 25 October 2007

Delayed allogeneic skin graft rejection in CD26-deficient mice.
Zhao, X. and Zhang, K. and Daniel, P. and Wisbrun, N. and Fuchs, H. and Fan, H.
Cellular and Molecular Immunology 16 (6): 557-567. June 2019

BCR-ABL positive cells and chronic myeloid leukemia in immune suppressed organ transplant recipients.
le Coutre, P. and Reinke, P. and Neuhaus, R. and Trappe, R. and Ringel, F. and Lalancette, M. and Hemmati, P.G. and Doerken, B. and Daniel, P.T.
European Journal of Haematology 84 (1): 26-33. 1 January 2010

Post-transplantation chronic myeloid leukemia.
le Coutre, P. and Schwarz, M. and Daniel, P. and Doerken, B.
Clinical Advances in Hematology & Oncology 9 (8): 627-629. August 2011

Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway.
von Haefen, C. and Gillissen, B. and Hemmati, P.G. and Wendt, J. and Guener, D. and Mrozek, A. and Belka, C. and Doerken, B. and Daniel, P.T.
Oncogene 23 (50): 8320-8332. 27 September 2004

Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway.
von Haefen, C. and Wendt, J. and Semini, G. and Sifringer, M. and Belka, C. and Radetzki, S. and Reutter, W. and Daniel, P.T. and Danker, K.
Apoptosis 16 (6): 636-651. March 2011

Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.
von Haefen, C. and Wieder, T. and Essmann, F. and Schulze-Osthoff, K. and Doerken, B. and Daniel, P.T.
Oncogene 22 (15): 2236-2247. 1 April 2003

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.
von Haefen, C. and Wieder, T. and Gillissen, B. and Staerck, L. and Graupner, V. and Doerken, B. and Daniel, P.T.
Oncogene 21 (25): 4009-4019. 6 June 2002

Daumke, Oliver

Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A. and Xavier, A. and Abu Lubad, M. and Sigulla, J. and Kessler, M. and Hurwitz, R. and Meyer, T.F.
EBioMedicine 23 : 100-110. September 2017

Membrane fission by dynamin: what we know and what we need to know.
Antonny, B. and Burd, C. and De Camilli, P. and Chen, E. and Daumke, O. and Faelber, K. and Ford, M. and Frolov, V.A. and Frost, A. and Hinshaw, J.E. and Kirchhausen, T. and Kozlov, M.M. and Lenz, M. and Low, H.H. and McMahon, H. and Merrifield, C. and Pollard, T.D. and Robinson, P.J. and Roux, A. and Schmid, S.
EMBO Journal 35 (21): 2270-2284. 2 November 2016

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A. and Roske, Y. and Barth, C. and Lleras Forero, L. and Bravo-Rodriguez, K. and Redel, Al. and Kostova, S. and McShane, E. and Opitz, R. and Faelber, K. and Rau, K. and Mielke, T. and Daumke, O. and Selbach, M. and Sanchez-Garcia, E. and Rocks, O. and Panáková, D. and Heinemann, U. and Wanker, E.E.
Nature Communications 7 : 13047. 20 October 2016

Dynamics of the ligand binding domain layer during AMPA receptor activation.
Baranovic, J. and Chebli, M. and Salazar, H. and Carbone, A.L. and Faelber, K. and Lau, A.Y. and Daumke, O. and Plested, A.J.R.
Biophysical Journal 110 (4): 896-911. 23 February 2016

A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand, J. and Smith, E.S.J. and Schwefel, D. and Lapatsina, L. and Poole, K. and Omerbasic, D. and Kozlenkov, A. and Behlke, J. and Lewin, G.R. and Daumke, O.
EMBO Journal 31 (17): 3635-3646. 29 August 2012

Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach.
Chakrabarti, P.P. and Daumke, O. and Suveyzdis, Y. and Koetting, C. and Gerwert, K. and Wittinghofer, A.
Journal of Molecular Biology 367 (4): 983-95. 6 April 2007

Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module.
Daumke, O. and Gao, S. and von der Malsburg, A. and Haller, O. and Kochs, G.
Small GTPases 1 (1): 62-64. July 2010

Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
Daumke, O. and Lundmark, R. and Vallis, Y. and Martens, S. and Butler, P.J.G. and McMahon, H.T.
Nature 449 (7164): 923-927. 3 October 2007

Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily.
Daumke, O. and Praefcke, G.J.
Biopolymers 105 (8): 580-593. August 2016

Structural insights into membrane fusion at the endoplasmic reticulum.
Daumke, O. and Praefcke, G.J.
Proceedings of the National Academy of Sciences of the United States of America 108 (6): 2175-2176. 8 February 2011

BAR domain scaffolds in dynamin-mediated membrane fission.
Daumke, O. and Roux, A. and Haucke, V.
Cell 156 (5): 882-892. 27 February 2014

Mitochondrial homeostasis: How do dimers of mitofusins mediate mitochondrial fusion?
Daumke, O. and Roux, A.
Current Biology 27 (9): R353-R356. 8 May 2017

Protein-mediated membrane remodeling.
Daumke, O. and Unger, V.M.
Journal of Structural Biology 196 (1): 1-2. October 2016

Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.
Dick, A. and Graf, L. and Olal, D. and von der Malsburg, A. and Gao, S. and Kochs, G. and Daumke, O.
Journal of Biological Chemistry 290 (20): 12779-12792. 15 May 2015

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. and Czajkowski, M.T. and Barth, C. and Müller, P.M. and McShane, E. and Grunwald, S. and Beaudette, P. and Mecklenburg, N. and Volkmer, R. and Zühlke, K. and Dittmar, G. and Selbach, M. and Hammes, A. and Daumke, O. and Klussmann, E. and Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Structural insights into dynamin-mediated membrane fission.
Faelber, K. and Held, M. and Gao, S. and Posor, Y. and Haucke, V. and Noe, F. and Daumke, O.
Structure 20 (10): 1621-1628. 10 October 2012

Crystal structure of nucleotide-free dynamin.
Faelber, K. and Posor, Y. and Gao, S. and Held, M. and Roske, Y. and Schulze, D. and Haucke, V. and Noe, F. and Daumke, O.
Nature 477 (7366): 556-560. 29 September 2011

Struktur und Funktion des mechanochemischen Motorproteins Dynamin.
Faelber, K. and Daumke, O.
BIOspektrum 24 (5): 481-483. September 2018

Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Faelber, K. and Dietrich, L. and Noel, J.K. and Wollweber, F. and Pfitzner, A.K. and Mühleip, A. and Sánchez, R. and Kudryashev, M. and Chiaruttini, N. and Lilie, H. and Schlegel, J. and Rosenbaum, E. and Hessenberger, M. and Matthaeus, C. and Kunz, S. and von der Malsburg, A. and Noé, F. and Roux, A. and van der Laan, M. and Kühlbrandt, W. and Daumke, O.
Nature 571 (7765): 429-433. 18 July 2019

Oligomerization of dynamin superfamily proteins in health and disease.
Faelber, K. and Gao, S. and Held, M. and Posor, Y. and Haucke, V. and Noé, F. and Daumke, O.
Progress in Molecular Biology and Translational Science 117 : 411-443. 2013

Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer.
Francy, C.A. and Clinton, R.W. and Froehlich, C. and Murphy, C. and Mears, J.A.
Scientific Reports 7 (1): 10744. 6 September 2017

Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein.
Fröhlich, C. and Grabiger, S. and Schwefel, D. and Faelber, K. and Rosenbaum, E. and Mears, J. and Rocks, O. and Daumke, O.
EMBO Journal 32 (9): 1280-1292. 2 May 2013

Structure of myxovirus resistance protein A reveals intra- and intermolecular domain interactions required for the antiviral function.
Gao, S. and von der Malsburg, A. and Dick, A. and Faelber, K. and Schroeder, G.F. and Haller, O. and Kochs, G. and Daumke, O.
Immunity 35 (4): 514-525. 28 October 2011

Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao, S. and von der Malsburg, A. and Paeschke, S. and Behlke, J. and Haller, O. and Kochs, G. and Daumke, O.
Nature 465 (7297): 502-506. 27 May 2010

New role for the (pro)renin receptor in T cell development.
Geisberger, S. and Maschke, U. and Gebhardt, M. and Kleinewietfeld, M. and Manzel, A. and Linker, R.A. and Chidgey, A. and Dechend, R. and Nguyen, G. and Daumke, O. and Muller, D.N. and Wright, M.D. and Binger, K.J.
Blood 126 (4): 504-507. 23 July 2015

Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.
Graf, L. and Dick, A. and Sendker, F. and Barth, E. and Marz, M. and Daumke, O. and Kochs, G.
Journal of Biological Chemistry 293 (9): 3056-3072. 2 March 2018

AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Götz, F. and Roske, Y. and Schulz, M.S. and Autenrieth, K. and Bertinetti, D. and Faelber, K. and Zühlke, K. and Kreuchwig, A. and Kennedy, E. and Krause, G. and Daumke, O. and Herberg, F.W. and Heinemann, U. and Klussmann, E.
Biochemical Journal 473 (13): 1881-1894. 28 June 2016

Dynamin-like MxA GTPase: Structural insights into oligomerization and implications for antiviral activity.
Haller, O. and Gao, S. and von der Malsburg, A. and Daumke, O. and Kochs, G.
Journal of Biological Chemistry 285 (37): 28419-28424. 10 September 2010

Structure of a classical MHC class I molecule that binds "non-classical" ligands.
Hee, C.S. and Gao, S. and Loll, B. and Miller, M.M. and Uchanska-Ziegler, B. and Daumke, O. and Ziegler, A.
PLoS Biology 8 (12): e1000557. 7 December 2010

Expression, purification and preliminary X-ray crystallographic analysis of the chicken MHC class I molecule YF1*7.1.
Hee, C.S. and Gao, S. and Miller, M.M. and Goto, R.M. and Ziegler, A. and Daumke, O. and Uchanska-Ziegler, B.
Acta Crystallographica Section F 65 (Pt 4): 422-425. 1 April 2009

Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature.
Henne, W.M. and Kent, H.M. and Ford, M.G.J. and Hegde, B.G. and Daumke, O. and Butler, P.J.G. and Mittal, R. and Langen, R. and Evans, P.R. and McMahon, H.T.
Structure 15 (7): 839-52. July 2007

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
Hessenberger, M. and Zerbes, R.M. and Rampelt, H. and Kunz, S. and Xavier, A.H. and Purfürst, B. and Lilie, H. and Pfanner, N. and van der Laan, M. and Daumke, O.
Nature Communications 8 : 15258. 31 May 2017

Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Jerke, U. and Marino, S.F. and Daumke, O. and Kettritz, R.
Scientific Reports 7 : 43328. 27 February 2017

Stomatin-domain proteins.
Lapatsina, L. and Brand, J. and Poole, K. and Daumke, O. and Lewin, G.R.
European Journal of Cell Biology 91 (4): 240-245. April 2012

Using SMOG 2 to simulate complex biomolecular assemblies.
Levi, M. and Bandarkar, P. and Yang, H. and Wang, A. and Mohanty, U. and Noel, J.K. and Whitford, P.C.
Methods in Molecular Biology 2022 : 129-151. 2019

Studying ribosome dynamics with simplified models.
Levi, M. and Noel, J.K. and Whitford, P.C.
Methods 162-163 : 128-140. 1 June 2019

Pathophysiological role of caveolae in hypertension.
Lian, X. and Matthaeus, C. and Kaßmann, M. and Daumke, O. and Gollasch, M.
Frontiers in Medicine 6 : 153. July 2019

Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose.
Licht, A. and Bulut, H. and Scheffel, F.M. and Daumke, O. and Wehmeier, U.F. and Saenger, W. and Schneider, E. and Vahedi-Faridi, A.
Journal of Molecular Biology 406 (1): 92-105. 11 February 2011

Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill.
Lin, X. and Noel, J.K. and Wang, Q. and Ma, J. and Onuchic, J.N.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): E7905-E7913. 21 August 2018

Lowered pH leads to fusion peptide release and a highly dynamic intermediate of influenza hemagglutinin.
Lin, X.C. and Noel, J.K. and Wang, Q.H. and Ma, J.P. and Onuchic, J.N.
Journal of Physical Chemistry B 120 (36): 9654-9660. 15 September 2016

Structural basis for membrane tethering by a bacterial dynamin-like pair.
Liu, J. and Noel, J.K. and Low, H.H.
Nature Communications 9 (1): 3345. 21 August 2018

Sarcolemmal repair is a slow process and includes EHD2.
Marg, A. and Schoewel, V. and Timmel, T. and Schulze, A. and Shah, C. and Daumke, O. and Spuler, S.
Traffic 13 (9): 1286-1294. September 2012

A complex water network contributes to high-affinity binding in an antibody-antigen interface.
Marino, S.F. and Olal, D. and Daumke, O.
Data in Brief 6 : 394-397. March 2016

EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake.
Matthäus, C. and Lahmann, I. and Kunz, S. and Jonas, W. and Alves Melo, A. and Lehmann, M. and Larsson, E. and Lundmark, R. and Kern, M. and Blüher, M. and Müller, D.N. and Haucke, V. and Schürmann, A. and Birchmeier, C. and Daumke, O.
bioRxiv : 511709. 7 March 2019

Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Melo, A.A. and Hegde, B.G. and Shah, C. and Larsson, E. and Isas, J.M. and Kunz, S. and Lundmark, R. and Langen, R. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 114 (22): 5629-5634. 30 May 2017

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization.
Moren, B. and Shah, C. and Howes, M.T. and Schieber, N.L. and McMahon, H.T. and Parton, R.G. and Daumke, O. and Lundmark, R.
Molecular Biology of the Cell 23 (7): 1316-1329. 9 February 2012

SMOG 2: A versatile software package for generating structure-based models.
Noel, J.K. and Levi, M. and Raghunathan, M. and Lammert, H. and Hayes, R.L. and Onuchic, J.N. and Whitford, P.C.
PLoS Computational Biology 12 (3): e1004794. 10 March 2016

Sequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamics.
Noel, J.K. and Morcos, F. and Onuchic, J.N.
F1000 Research 5 (F1000 Faculty Rev): 106. 26 January 2016

Polymer-like model to study the dynamics of dynamin filaments on deformable membrane tubes.
Noel, J.K. and Noé, F. and Daumke, O. and Mikhailov, A.S.
bioRxiv : 686873. 28 June 2019

How EF-Tu can contribute to efficient proofreading of aa-tRNA by the ribosome.
Noel, J.K. and Whitford, P.C.
Nature Communications 7 : 13314. 31 October 2016

Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Oden, F. and Marino, S.F. and Brand, J. and Scheu, S. and Kriegel, C. and Olal, D. and Takvorian, A. and Westermann, J. and Yilmaz, B. and Hinz, M. and Daumke, O. and Höpken, U.E. and Müller, G. and Lipp, M.
Molecular Oncology 9 (7): 1348-1358. August 2015

Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation.
Olal, D. and Daumke, O.
Cell Reports 14 (9): 2092-2099. 8 March 2016

Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein.
Olal, D. and Dick, A. and Woods, V.L. and Liu, T. and Li, S. and Devignot, S. and Weber, F. and Saphire, E.O. and Daumke, O.
Nucleic Acids Research 42 (9): 6025-6037. 14 May 2014

Quantitative GTPase affinity purification identifies Rho family protein interaction partners.
Paul, F. and Zauber, H. and von Berg, L. and Rocks, O. and Daumke, O. and Selbach, M.
Molecular & Cellular Proteomics 16 (1): 73-85. 1 January 2017

Crystal structure of the dynamin tetramer.
Reubold, T.F. and Faelber, K. and Plattner, N. and Posor, Y. and Ketel, K. and Curth, U. and Schlegel, J. and Anand, R. and Manstein, D.J. and Noé, F. and Haucke, V. and Daumke, O. and Eschenburg, S.
Nature 525 (7569): 404-408. 17 September 2015

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
Schrade, K. and Tröger, J. and Eldahshan, A. and Zühlke, K. and Abdul Azeez, K.R. and Elkins, J.M. and Neuenschwander, M. and Oder, A. and Elkewedi, M.M.H. and Jaksch, S. and Andrae, K. and Li, J. and Fernandes, J. and Müller, P.M. and Grunwald, S. and Marino, S.F. and Vukićević, T. and Eichhorst, J. and Wiesner, B. and Weber, M. and Kapiloff, M. and Rocks, O. and Daumke, O. and Wieland, T. and Knapp, S. and von Kries, J.P. and Klussmann, E.
PLoS ONE 13 (1): e0191423. 26 January 2018

Roquin binding to target mRNAs involves a winged helix-turn-helix motif.
Schuetz, A. and Murakawa, Y. and Rosenbaum, E. and Landthaler, M. and Heinemann, U.
Nature Communications 5 : 5701. 11 December 2014

The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion.
Schulte, K. and Pawlowski, N. and Faelber, K. and Fröhlich, C. and Howard, J. and Daumke, O.
BMC Biology 14 (1): 14. 2 March 2016

Structural basis for aryl hydrocarbon receptor-mediated gene activation.
Schulte, K.W. and Green, E. and Wilz, A. and Platten, M. and Daumke, O.
Structure 25 (7): 1025-1033. 5 July 2017

GTP-dependent scaffold formation in the GTPase of Immunity Associated Protein family.
Schwefel, D. and Daumke, O.
Small GTPases 2 (1): 27-30. January 2011

Purification, crystallization and preliminary X-ray analysis of human GIMAP2.
Schwefel, D. and Froehlich, C. and Daumke, O.
Acta Crystallographica Section F 66 (6): 725-729. 1 June 2010

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Schwefel, D. and Froehlich, C. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Aravind, L. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 107 (47): 20299-20304. 23 November 2010

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel, D. and Arasu, B.S. and Marino, S.F. and Lamprecht, B. and Köchert, K. and Rosenbaum, E. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Rocks, O. and Mathas, S. and Daumke, O.
Structure 21 (4): 550-559. 2 April 2013

Host cell interactome of tyrosine-phosphorylated bacterial proteins.
Selbach, M. and Paul, F.E. and Brandt, S. and Guye, P. and Daumke, O. and Backert, S. and Dehio, C. and Mann, M.
Cell Host & Microbe 5 (4): 397-403. 23 April 2009

Phosphorylation of PACSIN2 by protein kinase C triggers the removal of caveolae from the plasma membrane.
Senju, Y. and Rosenbaum, E. and Shah, C. and Hamada-Nakahara, S. and Itoh, Y. and Yamamoto, K. and Hanawa-Suetsugu, K. and Daumke, O. and Suetsugu, S.
Journal of Cell Science 128 (15): 2766-2780. 1 August 2015

Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C. and Hegde, B.G. and Morén, B. and Behrmann, E. and Mielke, T. and Moenke, G. and Spahn, C.M. and Lundmark, R. and Daumke, O. and Langen, R.
Structure 22 (3): 409-420. 4 March 2014

A SEPT1-based scaffold is required for Golgi integrity and function.
Song, K. and Gras, C. and Capin, G. and Gimber, N. and Lehmann, M. and Mohd, S. and Puchkov, D. and Rödiger, M. and Wilhelmi, I. and Daumke, O. and Schmoranzer, J. and Schürmann, A. and Krauss, M.
Journal of Cell Science 132 (3): jcs225557. 1 February 2019

Molecular simulations suggest a force-dependent mechanism of vinculin activation.
Sun, L. and Noel, J.K. and Levine, H. and Onuchic, J.N.
Biophysical Journal 113 (8): 1697-1710. 17 October 2017

53BP1 supports immunoglobulin class switch recombination independently of its DNA double-strand break end protection function.
Sundaravinayagam, D. and Rahjouei, A. and Andreani, M. and Tupiņa, D. and Balasubramanian, S. and Saha, T. and Delgado-Benito, V. and Coralluzzo, V. and Daumke, O. and Di Virgilio, M.
Cell Reports 28 (6): 1389-1399. 6 August 2019

How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates.
Turco, E. and Witt, M. and Abert, C. and Bock-Bierbaum, T. and Su, M.Y. and Trapannone, R. and Sztacho, M. and Danieli, A. and Shi, X. and Zaffagnini, G. and Gamper, A. and Schuschnig, M. and Fracchiolla, D. and Bernklau, D. and Romanov, J. and Hartl, M. and Hurley, J.H. and Daumke, O. and Martens, S.
Autophagy 15 (8): 1475-1477. August 2019

FIP200 claw domain binding to p62 promotes autophagosome formation at ubiquitin condensates.
Turco, E. and Witt, M. and Abert, C. and Bock-Bierbaum, T. and Su, M.Y. and Trapannone, R. and Sztacho, M. and Danieli, A. and Shi, X. and Zaffagnini, G. and Gamper, A. and Schuschnig, M. and Fracchiolla, D. and Bernklau, D. and Romanov, J. and Hartl, M. and Hurley, J.H. and Daumke, O. and Martens, S.
Molecular Cell 74 (2): 330-346. 18 April 2019

Functional mapping of human dynamin-1-like GTPase domain based on X-ray structure analyses.
Wenger, J. and Klinglmayr, E. and Fröhlich, C. and Eibl, C. and Gimeno, A. and Hessenberger, M. and Puehringer, S. and Daumke, O. and Goettig, P.
PLoS ONE 8 (8): e71835. 19 August 2013

Anisotropic fluctuations in the ribosome determine tRNA kinetics.
Yang, H. and Noel, J.K. and Whitford, P.C.
Journal of Physical Chemistry B 121 (47): 10593-10601. 30 November 2017

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L. and Kärgel, E. and Franke, V. and McShane, E. and Schulz-Beiss, K.W. and Patone, G. and Schleussner, N. and Kolesnichenko, M. and Hübner, N. and Daumke, O. and Selbach, M. and Akalin, A. and Mathas, S. and Scheidereit, C.
Blood 133 (13): 1489-1494. 28 March 2019

De la Rosa, Kathrin

B-cell biology and development.
Pieper, K. and Grimbacher, B. and Eibel, H.
Journal of Allergy and Clinical Immunology 131 (4): 959-971. April 2013

A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.
Pieper, K. and Rizzi, M. and Speletas, M. and Smulski, C.R. and Sic, H. and Kraus, H. and Salzer, U. and Fiala, G.J. and Schamel, W.W. and Lougaris, V. and Plebani, A. and Hammarstrom, L. and Recher, M. and Germenis, A.E. and Grimbacher, B. and Warnatz, K. and Rolink, A.G. and Schneider, P. and Notarangelo, L.D. and Eibel, H.
Journal of Allergy and Clinical Immunology 133 (4): 1222-1225. April 2014

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Pieper, K. and Tan, J. and Piccoli, L. and Foglierini, M. and Barbieri, S. and Chen, Y. and Silacci-Fregni, C. and Wolf, T. and Jarrossay, D. and Anderle, M. and Abdi, A. and Ndungu, F.M. and Doumbo, O.K. and Traore, B. and Tran, T.M. and Jongo, S. and Zenklusen, I. and Crompton, P.D. and Daubenberger, C. and Bull, P.C. and Sallusto, F. and Lanzavecchia, A.
Nature 548 (7669): 597-601. 31 August 2017

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
Tan, J. and Pieper, K. and Piccoli, L. and Abdi, A. and Foglierini, M. and Geiger, R. and Tully, C.M. and Jarrossay, D. and Ndungu, F.M. and Wambua, J. and Bejon, P. and Silacci Fregni, C. and Fernandez-Rodriguez, B. and Barbieri, S. and Bianchi, S. and Marsh, K. and Thathy, V. and Corti, D. and Sallusto, F. and Bull, P. and Lanzavecchia, A.
Nature 529 (7584): 105-109. 7 January 2016

Deubzer, Hedwig (ECRC)

Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.
Arnhold, V. and Schmelz, K. and Proba, J. and Winkler, A. and Wünschel, J. and Toedling, J. and Deubzer, H.E. and Künkele, A. and Eggert, A. and Schulte, J.H. and Hundsdoerfer, P.
Oncotarget 9 (2): 2304-2319. 2018

Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition.
Blattmann, C. and Oertel, S. and Ehemann, V. and Thiemann, M. and Huber, P.E. and Bischof, M. and Witt, O. and Deubzer, H.E. and Kulozik, A.E. and Debus, J. and Weber, K.J.
International Journal of Radiation Oncology, Biology, Physics 78 (1): 237-245. 1 September 2010

Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.
Brockmann, M. and Poon, E. and Berry, T. and Carstensen, A. and Deubzer, H.E. and Rycak, L. and Jamin, Y. and Thway, K. and Robinson, S.P. and Roels, F. and Witt, O. and Fischer, M. and Chesler, L. and Eilers, M.
Cancer Cell 24 (1): 75-89. 8 July 2013

Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells.
Deubzer, H. and Busche, B. and Rönndahl, G. and Eikel, D. and Michaelis, M. and Cinatl, J. and Schulze, S. and Nau, H. and Witt, O.
Leukemia Research 30 (9): 1167-1175. September 2006

Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro.
Deubzer, H.E. and Ehemann, V. and Kulozik, A.E. and Westermann, F. and Savelyeva, L. and Kopp-Schneider, A. and Riester, D. and Schwab, M. and Witt, O.
Cancer Letters 264 (1): 21-28. 8 June 2008

Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.
Deubzer, H.E. and Ehemann, V. and Westermann, F. and Heinrich, R. and Mechtersheimer, G. and Kulozik, A.E. and Schwab, M. and Witt, O.
International Journal of Cancer 122 (8): 1891-900. 15 April 2008

Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae.
Deubzer, H.E. and Obaro, S.K. and Newman, V.O. and Adegbola, R.A. and Greenwood, B.M. and Henderson, D.C.
Journal of Infectious Diseases 190 (10): 1758-1761. 15 November 2004

HDAC11 is a novel drug target in carcinomas.
Deubzer, H.E. and Schier, M.C. and Oehme, I. and Lodrini, M. and Haendler, B. and Sommer, A. and Witt, O.
International Journal of Cancer 132 (9): 2200-2208. 1 May 2013

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Ecker, J. and Oehme, I. and Mazitschek, R. and Korshunov, A. and Kool, M. and Hielscher, T. and Kiss, J. and Selt, F. and Konrad, C. and Lodrini, M. and Deubzer, H.E. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Witt, O. and Milde, T.
Acta Neuropathologica Communications 3 : 22. 3 April 2015

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.
Fabian, J. and Lodrini, M. and Oehme, I. and Schier, M.C. and Thole, T.M. and Hielscher, T. and Kopp-Schneider, A. and Opitz, L. and Capper, D. and von Deimling, A. and Wiegand, I. and Milde, T. and Mahlknecht, U. and Westermann, F. and Popanda, O. and Roels, F. and Hero, B. and Berthold, F. and Fischer, M. and Kulozik, A.E. and Witt, O. and Deubzer, H.E.
Cancer Research 74 (9): 2604-2616. 1 May 2014

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Fabian, J. and Opitz, D. and Althoff, K. and Lodrini, M. and Hero, B. and Volland, R. and Beckers, A. and de Preter, K. and Decock, A. and Patil, N. and Abba, M. and Kopp-Schneider, A. and Astrahantseff, K. and Wünschel, J. and Pfeil, S. and Ercu, M. and Künkele, A. and Hu, J. and Thole, T. and Schweizer, L. and Mechtersheimer, G. and Carter, D. and Cheung, B.B. and Popanda, O. and von Deimling, A. and Koster, J. and Versteeg, R. and Schwab, M. and Marshall, G.M. and Speleman, F. and Erb, U. and Zoeller, M. and Allgayer, H. and Simon, T. and Fischer, M. and Kulozik, A.E. and Eggert, A. and Witt, O. and Schulte, J.H. and Deubzer, H.E.
Oncotarget 7 (41): 66344-66359. 11 October 2016

RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.
Gottlieb, A. and Althoff, K. and Grunewald, L. and Thor, T. and Odersky, A. and Schulte, M. and Deubzer, H.E. and Heukamp, L. and Eggert, A. and Schramm, A. and Schulte, J.H. and Künkele, A.
Oncotarget 8 (17): 27882-27891. 25 April 2017

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
Han, Y. and Lindner, S. and Bei, Y. and Dorado Garcia, H. and Timme, N. and Althoff, K. and Odersky, A. and Schramm, A. and Lissat, A. and Künkele, A. and Deubzer, H.E. and Eggert, A. and Schulte, J.H. and Henssen, A.G.
Cancer Letters 445 : 24-33. 31 March 2019

CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programs in neuroblastoma cells.
Henrich, K.O. and Bauer, T. and Schulte, J. and Ehemann, V. and Deubzer, H. and Gogolin, S. and Muth, D. and Fischer, M. and Benner, A. and König, R. and Schwab, M. and Westermann, F.
Cancer Research 71 (8): 3142-3151. 15 April 2011

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma.
Kocak, H. and Ackermann, S. and Hero, B. and Kahlert, Y. and Oberthuer, A. and Juraeva, D. and Roels, F. and Theissen, J. and Westermann, F. and Deubzer, H. and Ehemann, V. and Brors, B. and Odenthal, M. and Berthold, F. and Fischer, M.
Cell Death & Disease 4 : e586. 11 April 2013

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.
Künkele, A. and De Preter, K. and Heukamp, L. and Thor, T. and Pajtler, K.W. and Hartmann, W. and Mittelbronn, M. and Grotzer, M.A. and Deubzer, H.E. and Speleman, F. and Schramm, A. and Eggert, A. and Schulte, J.H.
Neuro-Oncology 14 (7): 859-869. 1 July 2012

Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells.
Lacroix, J. and Leuchs, B. and Li, J. and Hristov, G. and Deubzer, H.E. and Kulozik, A.E. and Rommelaere, J. and Schlehofer, J.R. and Witt, O.
International Journal of Cancer 127 (5): 1230-1239. 1 September 2010

Neuroblastoma imaging.
Ley, S. and Ley-Zaporozhan, J. and Günther, P. and Deubzer, H.E. and Witt, O. and Schenk, J.P.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 183 (3): 217-225. March 2011

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
Lodrini, M. and Oehme, I. and Schroeder, C. and Milde, T. and Schier, M.C. and Kopp-Schneider, A. and Schulte, J.H. and Fischer, M. and De Preter, K. and Pattyn, F. and Castoldi, M. and Muckenthaler, M.U. and Kulozik, A.E. and Westermann, F. and Witt, O. and Deubzer, H.E.
Nucleic Acids Research 41 (12): 6018-6033. 1 July 2013

Minichromosome maintenance complex is a critical node in the miR-183 signaling network of MYCN-amplified neuroblastoma cells.
Lodrini, M. and Poschmann, G. and Schmidt, V. and Wünschel, J. and Dreidax, D. and Witt, O. and Höfer, T. and Meyer, H.E. and Stühler, K. and Eggert, A. and Deubzer, H.E.
Journal of Proteome Research 15 (7): 2178-2186. 1 July 2016

Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma.
Lodrini, M. and Sprüssel, A. and Astrahantseff, K. and Tiburtius, D. and Konschak, R. and Lode, H.N. and Fischer, M. and Keilholz, U. and Eggert, A. and Deubzer, H.E.
Oncotarget 8 (49): 85234-85251. 17 October 2017

Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins.
Michaelis, M. and Bliss, J. and Arnold, S.C. and Hinsch, N. and Rothweiler, F. and Deubzer, H.E. and Witt, O. and Langer, K. and Doerr, H.W. and Wels, W.S. and Cinatl, J.
Clinical Cancer Research 14 (20): 6531-6537. 16 October 2008

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.
Michaelis, M. and Kleinschmidt, M.C. and Barth, S. and Rothweiler, F. and Geiler, J. and Breitling, R. and Mayer, B. and Deubzer, H. and Witt, O. and Kreuter, J. and Doerr, H.W. and Cinatl, J. and Cinatl, J.
Biochemical Pharmacology 79 (2): 130-136. 15 January 2010

Nestin expression identifies ependymoma patients with poor outcome.
Milde, T. and Hielscher, T. and Witt, H. and Kool, M. and Mack, S.C. and Deubzer, H.E. and Oehme, I. and Lodrini, M. and Benner, A. and Taylor, M.D. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Witt, O. and Korshunov, A.
Brain Pathology 22 (6): 848-860. November 2012

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
Milde, T. and Kleber, S. and Korshunov, A. and Witt, H. and Hielscher, T. and Koch, P. and Kopp, H.G. and Jugold, M. and Deubzer, H.E. and Oehme, I. and Lodrini, M. and Gröne, H.J. and Benner, A. and Brüstle, O. and Gilbertson, R.J. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Martin-Villalba, A. and Witt, O.
Acta Neuropathologica 122 (5): 637-650. November 2011

HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.
Milde, T. and Lodrini, M. and Savelyeva, L. and Korshunov, A. and Kool, M. and Brueckner, L.M. and Antunes, A.S.L.M. and Oehme, I. and Pekrun, A. and Pfister, S.M. and Kulozik, A.E. and Witt, O. and Deubzer, H.E.
Journal of Neuro-Oncology 110 (3): 335-348. December 2012

HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth.
Milde, T. and Oehme, I. and Korshunov, A. and Kopp-Schneider, A. and Remke, M. and Northcott, P. and Deubzer, H.E. and Lodrini, M. and Taylor, M.D. and von Deimling, A. and Pfister, S. and Witt, O.
Clinical Cancer Research 16 (12): 3240-3252. 15 June 2010

Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma.
Milde, T. and Pfister, S. and Korshunov, K. and Deubzer, H.E. and Oehme, I. and Ernst, A. and Starzinski-Powitz, A. and Seitz, A. and Lichter, P. and von Deimling, A. and Witt, O.
Genes Chromosomes & Cancer 48 (3): 229-238. March 2009

Serotype-specific pneumococcal antibodies in breast milk of Gambian women immunized with a pneumococcal polysaccharide vaccine during pregnancy.
Obaro, S.K. and Deubzer, H.E. and Newman, V.O. and Adegbola, R.A. and Greenwood, B.M. and Henderson, D.C.
Pediatric Infectious Disease Journal 23 (11): 1023-1029. November 2004

Targeting of HDAC8 and investigational inhibitors in neuroblastoma.
Oehme, I. and Deubzer, H.E. and Lodrini, M. and Milde, T. and Witt, O.
Expert Opinion on Investigational Drugs 18 (11): 1605-1617. November 2009

Histone deacetylase 8 in neuroblastoma tumorigenesis.
Oehme, I. and Deubzer, H.E. and Wegener, D. and Pickert, D. and Linke, J.P. and Hero, B. and Kopp-Schneider, A. and Westermann, F. and Ulrich, S.M. and von Deimling, A. and Fischer, M. and Witt, O.
Clinical Cancer Research 15 (1): 91-99. January 2009

Histone deacetylase 10 promotes autophagy-mediated cell survival.
Oehme, I. and Linke, J.P. and Böck, B.C. and Milde, T. and Lodrini, M. and Hartenstein, B. and Wiegand, I. and Eckert, C. and Roth, W. and Kool, M. and Kaden, S. and Gröne, H.J. and Schulte, J.H. and Lindner, S. and Hamacher-Brady, A. and Brady, N.R. and Deubzer, H.E. and Witt, O.
Proceedings of the National Academy of Sciences of the United States of America 110 (28): E2592-E2601. 9 July 2013

Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications.
Oevermann, L. and Zimmermann, C. and Voigt, S. and Künkele, A. and Lobitz, S. and Eggert, A. and Schulte, J.H. and Kaufer, B.B. and Deubzer, H.E.
Bone Marrow Transplantation 15 April 2019 (In Press)

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.
Pajtler, K.W. and Sadowski, N. and Ackermann, S. and Althoff, K. and Schönbeck, K. and Batzke, K. and Schäfers, S. and Odersky, A. and Heukamp, L. and Astrahantseff, K. and Künkele, A. and Deubzer, H.E. and Schramm, A. and Sprüssel, A. and Thor, T. and Lindner, S. and Eggert, A. and Fischer, M. and Schulte, J.H.
Oncotarget 8 (4): 6730-6741. 24 January 2017

Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation.
Rettig, I. and Koeneke, E. and Trippel, F. and Mueller, W.C. and Burhenne, J. and Kopp-Schneider, A. and Fabian, J. and Schober, A. and Fernekorn, U. and von Deimling, A. and Deubzer, H.E. and Milde, T. and Witt, O. and Oehme, I.
Cell Death & Disease 6 : e1657. 19 February 2015

Childhood cancer predisposition syndromes - a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.
Ripperger, T. and Bielack, S.S. and Borkhardt, A. and Brecht, I.B. and Burkhardt, B. and Calaminus, G. and Debatin, K.M. and Deubzer, H. and Dirksen, U. and Eckert, C. and Eggert, A. and Erlacher, M. and Fleischhack, G. and Frühwald, M.C. and Gnekow, A. and Goehring, G. and Graf, N. and Hanenberg, H. and Hauer, J. and Hero, B. and Hettmer, S. and von Hoff, K. and Horstmann, M. and Hoyer, J. and Illig, T. and Kaatsch, P. and Kappler, R. and Kerl, K. and Klingebiel, T. and Kontny, U. and Kordes, U. and Körholz, D. and Koscielniak, E. and Kramm, C.M. and Kuhlen, M. and Kulozik, A.E. and Lamottke, B. and Leuschner, I. and Lohmann, D.R. and Meinhardt, A. and Metzler, M. and Meyer, L.H. and Moser, O. and Nathrath, M. and Niemeyer, C.M. and Nustede, R. and Pajtler, K.W. and Paret, C. and Rasche, M. and Reinhardt, D. and Rieß, O. and Russo, A. and Rutkowski, S. and Schlegelberger, B. and Schneider, D. and Schneppenheim, R. and Schrappe, M. and Schroeder, C. and von Schweinitz, D. and Simon, T. and Sparber-Sauer, M. and Spix, C. and Stanulla, M. and Steinemann, D. and Strahm, B. and Temming, P. and Thomay, K. and von Bueren, A.O. and Vorwerk, P. and Witt, O. and Wlodarski, M. and Wössmann, W. and Zenker, M. and Zimmermann, S. and Pfister, S.M. and Kratz, C.P.
American Journal of Medical Genetics Part A 173 (4): 1017-1037. April 2017

Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells.
Schulte, J.H. and Kirfel, J. and Lim, S. and Schramm, A. and Friedrichs, N. and Deubzer, H.E. and Witt, O. and Eggert, A. and Buettner, R.
Cancer Letters 271 (1): 56-63. 18 November 2008

2017 GPOH guidelines for diagnosis and treatment of patients with neuroblastic tumors.
Simon, T. and Hero, B. and Schulte, J.H. and Deubzer, H. and Hundsdoerfer, P. and von Schweinitz, D. and Fuchs, J. and Schmidt, M. and Prasad, V. and Krug, B. and Timmermann, B. and Leuschner, I. and Fischer, M. and Langer, T. and Astrahantseff, K. and Berthold, F. and Lode, H. and Eggert, A.
Klinische Padiatrie 229 (3): 147-167. May 2017

Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole, T.M. and Toedling, J. and Sprüssel, A. and Pfeil, S. and Savelyeva, L. and Capper, D. and Messerschmidt, C. and Beule, D. and Groeneveld-Krentz, S. and Eckert, C. and Gambara, G. and Henssen, A.G. and Finkler, S. and Schulte, J.H. and Sieber, A. and Bluethgen, N. and Regenbrecht, C.R.A. and Künkele, A. and Lodrini, M. and Eggert, A. and Deubzer, H.E.
International Journal of Cancer 15 July 2019 (In Press)

HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells.
Wegener, D. and Deubzer, H.E. and Oehme, I. and Milde, T. and Hildmann, C. and Schwienhorst, A. and Witt, O.
Anti-Cancer Drugs 19 (9): 849-857. October 2008

Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay.
Wegener, D. and Hildmann, C. and Riester, D. and Schober, A. and Meyer-Almes, F.J. and Deubzer, H.E. and Oehme, I. and Witt, O. and Lang, S. and Jaensch, M. and Makarov, V. and Lange, C. and Busse, B. and Schwienhorst, A.
Biochemical Journal 413 (1): 143-150. 1 July 2008

Targeting histone deacetylases in neuroblastoma.
Witt, O. and Deubzer, H.E. and Lodrini, M. and Milde, T. and Oehme, I.
Current Pharmaceutical Design 15 (4): 436-447. 2009

HDAC family: What are the cancer relevant targets?
Witt, O. and Deubzer, H.E. and Milde, T. and Oehme, I.
Cancer Letters 277 (1): 8-21. 8 May 2009

Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma or leukemia.
Witt, O. and Milde, T. and Deubzer, H.E. and Oehme, I. and Witt, R. and Kulozik, A. and Eisenmenger, A. and Abel, U. and Karapanagiotou-Schenkel, I.
Klinische Padiatrie 224 (6): 398-403. October 2012

Di Virgilio, Michela

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K. and Kranz, A. and Fohgrub, J. and Jolly, A. and Bledau, A.S. and Di Virgilio, M. and Lesche, M. and Dahl, A. and Höfer, T. and Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018

A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y. and Malehmir, M. and Healy, M.E. and Bettermann, K. and Lorentzen, A. and Vucur, M. and Ahuja, A.K. and Böhm, F. and Mertens, J.C. and Shimizu, Y. and Frick, L. and Remouchamps, C. and Mutreja, K. and Kähne, T. and Sundaravinayagam, D. and Wolf, M.J. and Rehrauer, H. and Koppe, C. and Speicher, T. and Padrissa-Altés, S. and Maire, R. and Schattenberg, J.M. and Jeong, J.S. and Liu, Lei and Zwirner, S. and Boger, R. and Hüser, N. and Davis, R.J. and Müllhaupt, B. and Moch, H. and Schulze-Bergkamen, H. and Clavien, P.A. and Werner, S. and Borsig, L. and Luther, S.A. and Jost, P.J. and Weinlich, R. and Unger, K. and Behrens, A. and Hillert, L. and Dillon, C. and Di Virgilio, M. and Wallach, D. and Dejardin, E. and Zender, L. and Naumann, M. and Walczak, H. and Green, D.R. and Lopes, M. and Lavrik, I. and Luedde, T. and Heikenwalder, M. and Weber, A.
Cancer Cell 32 (3): 342-359. 11 September 2017

Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Bothmer, A. and Robbiani, D.F. and Di Virgilio, M. and Bunting, S.F. and Klein, I.A. and Feldhahn, N. and Barlow, J. and Chen, H.T. and Bosque, D. and Callen, E. and Nussenzweig, A. and Nussenzweig, M.C.
Molecular Cell 42 (3): 319-329. 6 May 2011

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Callen, E. and Di Virgilio, M. and Kruhlak, M.J. and Nieto-Soler, M. and Wong, N. and Chen, H.T. and Faryabi, R.B. and Polato, F. and Santos, M. and Starnes, L.M. and Wesemann, D.R. and Lee, J.E. and Tubbs, A. and Sleckman, B.P. and Daniel, J.A. and Ge, K. and Alt, F.W. and Fernandez-Capetillo, O. and Nussenzweig, M.C. and Nussenzweig, A.
Cell 153 (6): 1266-1280. 6 June 2013

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Callen, E. and Jankovic, M. and Wong, N. and Zha, S. and Chen, H.T. and Difilippantonio, S. and Di Virgilio, M. and Heidkamp, G. and Alt, F.W. and Nussenzweig, A. and Nussenzweig, M.
Molecular Cell 34 (3): 285-297. 15 May 2009

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V. and Rosen, D.B. and Wang, Q. and Gazumyan, A. and Pai, J.A. and Oliveira, T.Y. and Sundaravinayagam, D. and Zhang, W. and Andreani, M. and Keller, L. and Kieffer-Kwon, K.R. and Pękowska, A. and Jung, S. and Driesner, M. and Subbotin, R.I. and Casellas, R. and Chait, B.T. and Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72 (4): 636-649. 15 November 2018

Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Di Virgilio, M. and Callen, E. and Yamane, A. and Zhang, W. and Jankovic, M. and Gitlin, A.D. and Feldhahn, N. and Resch, W. and Oliveira, T.Y. and Chait, B.T. and Nussenzweig, A. and Casellas, R. and Robbiani, D.F. and Nussenzweig, M.C.
Science 339 (6120): 711-715. 8 February 2013

PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin.
Di Virgilio, M. and Ying, C.Y. and Gautier, J.
DNA Repair 8 (11): 1311-1320. 2 November 2009

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11.
Di Virgilio, M. and Gautier, J.
Journal of Cell Biology 171 (5): 765-771. 5 December 2005

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation.
Dorsett, Y. and McBride, K.M. and Jankovic, M. and Gazumyan, A. and Thai, T.H. and Robbiani, D.F. and Di Virgilio, M. and Reina San-Martin, B. and Heidkamp, G. and Schwickert, T.A. and Eisenreich, T. and Rajewsky, K. and Nussenzweig, M.C.
Immunity 28 (5): 630-638. 16 May 2008

Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.
Gazumyan, A. and Timachova, K. and Yuen, G. and Siden, E. and Di Virgilio, M. and Woo, E.M. and Chait, B.T. and Reina San-Martin, B. and Nussenzweig, M.C. and McBride, K.M.
Molecular and Cellular Biology 31 (3): 442-429. February 2011

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.
Klein, I.A. and Resch, W. and Jankovic, M. and Oliveira, T. and Yamane, A. and Nakahashi, H. and Di Virgilio, M. and Bothmer, A. and Nussenzweig, A. and Robbiani, D.F. and Casellas, R. and Nussenzweig, M.C.
Cell 147 (1): 95-106. 30 September 2011

An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex.
Kracker, S. and Di Virgilio, M. and Schwartzentruber, J. and Cuenin, C. and Forveille, M. and Deau, M.C. and McBride, K.M. and Majewski, J. and Gazumyan, A. and Seneviratne, S. and Grimbacher, B. and Kutukculer, N. and Herceg, Z. and Cavazzana, M. and Jabado, N. and Nussenzweig, M.C. and Fischer, A. and Durandy, A.
Journal of Allergy and Clinical Immunology 135 (4): 998-1007. April 2015

Novel pathogenic mechanisms of congenital insensitivity to pain with anhidrosis genetic disorder unveiled by functional analysis of neurotrophic tyrosine receptor kinase type 1/nerve growth factor receptor mutations.
Miranda, C. and Di Virgilio, M. and Selleri, S. and Zanotti, G. and Pagliardini, S. and Pierotti, M.A. and Greco, A.
Journal of Biological Chemistry 277 (8): 6455-6462. 22 February 2002

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.
Pavri, R. and Gazumyan, A. and Jankovic, M. and Di Virgilio, M. and Klein, I. and Ansarah-Sobrinho, C. and Resch, W. and Yamane, A. and Reina San-Martin, B. and Barreto, V. and Nieland, T.J. and Root, D.E. and Casellas, R. and Nussenzweig, M.C.
Cell 143 (1): 122-133. 1 October 2010

MAD2L2 promotes open chromatin in embryonic stem cells and derepresses the Dppa3 locus.
Rahjouei, A. and Pirouz, M. and Di Virgilio, M. and Kamin, D. and Kessel, M.
Stem Cell Reports 8 (4): 813-821. 11 April 2017

PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones.
Sander, S. and Chu, V.T. and Yasuda, T. and Franklin, A. and Graf, R. and Calado, D.P. and Li, S. and Imami, K. and Selbach, M. and Di Virgilio, M. and Bullinger, L. and Rajewsky, K.
Immunity 43 (6): 1075-1086. 15 December 2015

53BP1 supports immunoglobulin class switch recombination independently of its DNA double-strand break end protection function.
Sundaravinayagam, D. and Rahjouei, A. and Andreani, M. and Tupiņa, D. and Balasubramanian, S. and Saha, T. and Delgado-Benito, V. and Coralluzzo, V. and Daumke, O. and Di Virgilio, M.
Cell Reports 28 (6): 1389-1399. 6 August 2019

DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Volk, T. and Pannicke, U. and Reisli, I. and Bulashevska, A. and Ritter, J. and Björkman, A. and Schäffer, A.A. and Fliegauf, M. and Sayar, E.H. and Salzer, U. and Fisch, P. and Pfeifer, D. and Di Virgilio, M. and Cao, H. and Yang, F. and Zimmermann, K. and Keles, S. and Caliskaner, Z. and Güner, S.Ü. and Schindler, D. and Hammarström, L. and Rizzi, M. and Hummel, M. and Pan-Hammarstroem, Q. and Schwarz, K. and Grimbacher, B.
Human Molecular Genetics 24 (25): 7361-7372. 20 December 2015

Diecke, Sebastian (MDC/BIH)

Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes.
Burridge, P.W. and Diecke, S. and Matsa, E. and Sharma, A. and Wu, H. and Wu, J.C.
Methods in Molecular Biology 1353 : 119-130. 2016

SURF1 mutations causative of Leigh syndrome impair human neurogenesis.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Juettner, R. and Zink, A. and Mlody, B. and Glazar, P. and Secker, C. and Ciptasari, U.H. and Stenzel, W. and Hahn, T. and Diecke, S. and Priller, J. and Gotthardt, M. and Kuehn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
bioRxiv : 551390. 20 February 2019

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. and Ofenbauer, A. and Bulut, S.I. and Uyar, B. and Baytek, G. and Sommermeier, A. and Seelk, S. and He, M. and Hirsekorn, A. and Vucicevic, D. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
Kolundzic, E. and Ofenbauer, A. and Uyar, B. and Sommermeier, A. and Seelk, S. and He, M. and Baytek, G. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
bioRxiv : 185116. 6 September 2017

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. and Kirchner, M. and Uyar, B. and Cheng, J.Y. and Russo, G. and Hernandez-Miranda, L.R. and Szymborska, A. and Zauber, H. and Rudolph, I.M. and Willnow, T.E. and Akalin, A. and Haucke, V. and Gerhardt, H. and Birchmeier, C. and Kühn, R. and Krauss, M. and Diecke, S. and Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

The translational landscape of the human heart.
van Heesch, S. and Witte, F. and Schneider-Lunitz, V. and Schulz, J.F. and Adami, E. and Faber, A. and Kirchner, M. and Maatz, H. and Blachut, S. and Sandmann, C.L. and Kanda, M. and Worth, C.L. and Schafer, S. and Calviello, L. and Merriott, R. and Patone, G. and Hummel, O. and Wyler, E. and Obermayer, B. and Mücke, M.B. and Lindberg, E.L. and Trnka, F. and Memczak, S. and Schilling, M. and Felkin, L.E. and Barton, P.J.R. and Quaife, N.M. and Vanezis, K. and Diecke, S. and Mukai, M. and Mah, N. and Oh, S.J. and Kurtz, A. and Schramm, C. and Schwinge, D. and Sebode, M. and Harakalova, M. and Asselbergs, F.W. and Vink, A. and de Weger, R.A. and Viswanathan, S. and Widjaja, A.A. and Gärtner-Rommel, A. and Milting, H. and Dos Remedios, C. and Knosalla, C. and Mertins, P. and Landthaler, M. and Vingron, M. and Linke, W.A. and Seidman, J.G. and Seidman, C.E. and Rajewsky, N. and Ohler, U. and Cook, S.A. and Hubner, N.
Cell 178 (1): 242-260. 27 June 2019

Dietz, Rainer

B-Myb, a repressed trans-activating protein.
Ansieau, S. and Kowenz-Leutz, E. and Dechend, R. and Leutz, A.
Journal of Molecular Medicine 75 (11-12): 815-819. November 1997

Beta-catenin downregulation is required for adaptive cardiac remodeling.
Baurand, A. and Zelarayan, L. and Betney, R. and Gehrke, C. and Dunger, S. and Noack, C. and Busjahn, A. and Huelsken, J. and Taketo, M.M. and Birchmeier, W. and Dietz, R. and Bergmann, M.W.
Circulation Research 100 (9): 1353-1362. 11 May 2007

Ventricular remodeling after acute myocardial infarction.
Dietz, R. and Osterziel, K.J. and Willenbrock, R. and Gulba, D.C. and von Harsdorf, R.
Thrombosis and Haemostasis 82 (Suppl 1): 73-75. September 1999

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B. and Heuser, A. and Wichter, T. and Paul, M. and Basson, C.T. and McDermott, D.A. and Lerman, B.B. and Markowitz, S.M. and Ellinor, P.T. and MacRae, C.A. and Peters, S. and Grossmann, K.S. and Drenckhahn, J. and Michely, B. and Sasse-Klaassen, S. and Birchmeier, W. and Dietz, R. and Breithardt, G. and Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36 (11): 1162-1164. November 2004

Subacute coronary stent thrombosis in cancer patients.
Gross, C.M. and Posch, M.G. and Geier, C. and Olthoff, H. and Kraemer, J. and Dechend, R. and Dietz, R. and Oezcelik, C.
Journal of the American College of Cardiology 51 (12): 1232-1233. 25 March 2008

Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Henke, N. and Schmidt-Ullrich, R. and Dechend, R. and Park, J.K. and Qadri, F. and Wellner, M. and Obst, M. and Gross, V. and Dietz, R. and Luft, F.C. and Scheidereit, C. and Mueller, D.N.
Circulation Research 101 (3): 268-276. 3 August 2007

Insulin-like growth factor-I and risk of breast cancer.
Strohm, O. and Osterziel, K.J. and Dietz, R.
Lancet 352 (9126): 489-489. 8 August 1998

Cardiac magnetic resonance monitors reversible and irreversible myocardial injury in myocarditis.
Zagrosek, A. and Abdel-Aty, H. and Boye, P. and Wassmuth, R. and Messroghli, D. and Utz, W. and Rudolph, A. and Bohl, S. and Dietz, R. and Schulz-Menger, J.
JACC: Cardiovascular Imaging 2 (2): 131-138. February 2009

Dittmar, Gunnar

Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K. and von Delbrück, M. and Dittmar, G. and Scheffner, M. and Ziv, I. and Glickman, M.H. and Ciechanover, A. and Sommer, T.
Molecular Cell 50 (4): 528-539. 23 May 2013

PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
Dittmar, G. and Perez Hernandez, D. and Kowenz-Leutz, E. and Kirchner, M. and Kahlert, G. and Wesolowski, R. and Baum, K. and Knoblich, M. and Hofstätter, M. and Muller, A. and Wolf, J. and Reimer, U. and Leutz, A.
iScience 13 : 351-370. 29 March 2019

Protein Interaction Screen on Peptide Matrix (PRISMA) reveals interaction footprints and the PTM-dependent interactome of intrinsically disordered C/EBPβ.
Dittmar, G. and Perez-Hernandez, D. and Kowenz-Leutz, E. and Kirchner, M. and Kahlert, G. and Wesolowski, R. and Baum, K. and Knoblich, M. and Muller, A. and Wolf, J. and Reimer, U. and Leutz, A.
bioRxiv : 238709. 22 December 2017

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. and Czajkowski, M.T. and Barth, C. and Müller, P.M. and McShane, E. and Grunwald, S. and Beaudette, P. and Mecklenburg, N. and Volkmer, R. and Zühlke, K. and Dittmar, G. and Selbach, M. and Hammes, A. and Daumke, O. and Klussmann, E. and Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease.
Guenther, U.P. and Handoko, L. and Varon, R. and Stephani, U. and Tsao, C.Y. and Mendell, J.R. and Lützkendorf, S. and Hübner, C. and von Au, K. and Jablonka, S. and Dittmar, G. and Heinemann, U. and Schuetz, A. and Schuelke, M.
Journal of Molecular Medicine 87 (1): 31-41. January 2009

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz, M. and Stilmann, M. and Coel Arslan, S. and Khanna, K.K. and Dittmar, G. and Scheidereit, C.
Molecular Cell 40 (1): 63-74. 8 October 2010

Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F. and a Dzaye, O.D. and Hahn, A. and Yu, Y. and Scavetta, R.J. and Dittmar, G. and Kaczmarek, A.K. and Dunning, K.R. and Ricciardelli, C. and Rinnenthal, J.L. and Heppner, F.L. and Lehnardt, S. and Synowitz, M. and Wolf, S.A. and Kettenmann, H.
Neuro-Oncology 17 (2): 200-210. February 2015

Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Kirchner, F. and Schuetz, A. and Boldt, L.H. and Martens, K. and Dittmar, G. and Haverkamp, W. and Thierfelder, L. and Heinemann, U. and Gerull, B.
Circulation Cardiovascular Genetics 5 (4): 400-411. 1 August 2012

Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.
Kowenz-Leutz, E. and Pless, O. and Dittmar, G. and Knoblich, M. and Leutz, A.
EMBO Journal 29 (6): 1105-1115. 17 March 2010

MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.
Krause, C.J. and Popp, O. and Thirunarayanan, N. and Dittmar, G. and Lipp, M. and Mueller, G.
Oncotarget 7 (9): 10414-10432. 1 March 2016

Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs.
Leutz, A. and Pless, O. and Lappe, M. and Dittmar, G. and Kowenz-Leutz, E.
Transcription 2 (1): 3-8. January 2011

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D. and Pahuja, A. and Geers-Knörr, C. and Scheibe, R. and Nowak, M. and Hamati, J. and Köhncke, C. and Purfürst, B. and Kanashova, T. and Schmidt, S. and Glass, D.J. and Morano, I. and Heuser, A. and Kraft, T. and Bassel-Duby, R. and Olson, E.N. and Dittmar, G. and Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180. May 2016

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N. and Kolesnichenko, M. and Beaudette, P. and Popp, O. and Uyar, B. and Sun, W. and Tufan, A.B. and Perder, B. and Akalin, A. and Chen, W. and Mertins, P. and Dittmar, G. and Hinz, M. and Scheidereit, C.
EMBO Journal 37 (24): e98658. 14 December 2018

Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M. and Fan, D.N.Y. and Belenki, D. and Däbritz, J.H.M. and Zhao, Z. and Yu, Y. and Dörr, J.R. and Dimitrova, L. and Lenze, D. and Monteiro Barbosa, I.A. and Mendoza-Parra, M.A. and Kanashova, T. and Metzner, M. and Pardon, K. and Reimann, M. and Trumpp, A. and Dörken, B. and Zuber, J. and Gronemeyer, H. and Hummel, M. and Dittmar, G. and Lee, S. and Schmitt, C.A.
Nature 553 (7686): 96-100. 4 January 2018

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
Nowak, M. and Suenkel, B. and Porras, P. and Migotti, R. and Schmidt, F. and Kny, M. and Zhu, X. and Wanker, E.E. and Dittmar, G. and Fielitz, J. and Sommer, T.
Journal of Cell Science 132 (17): jcs233395. 6 September 2019

Translation of circRNAs.
Pamudurti, NR. and Bartok, O. and Jens, M. and Ashwal-Fluss, R. and Stottmeister, C. and Ruhe, L. and Hanan, M. and Wyler, E. and Perez-Hernandez, D. and Ramberger, E. and Shenzis, S. and Samson, M. and Dittmar, G. and Landthaler, M. and Chekulaeva, M. and Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

A differential proteome screening system for post-translational modification-dependent transcription factor interactions.
Pless, O. and Kowenz-Leutz, E. and Dittmar, G. and Leutz, A.
Nature Protocols 6 (3): 359-364. February 2011

Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K. and Shi, Y. and Jacobi, A. and Kräter, M. and Kalupa, M. and McGearey, A. and Mertlitz, S. and Cordes, S. and Schrezenmeier, J.F. and Mengwasser, J. and Westphal, S. and Perez-Hernandez, D. and Schmitt, C. and Dittmar, G. and Guck, J. and Penack, O.
Blood 129 (14): 2021-2032. 6 April 2017

Global analysis of cellular protein translation by pulsed SILAC.
Schwanhaeusser, B. and Gossen, M. and Dittmar, G. and Selbach, M.
Proteomics 9 (1): 205-209. January 2009

Ubiquitination.
Sommer, T. and Dittmar, G.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1964-1968. ISBN 3-540-44244-8 2006

RNF4-dependent oncogene activation by protein stabilization.
Thomas, J.J. and Abed, M. and Heuberger, J. and Novak, R. and Zohar, Y. and Beltra-Lopez, A.P. and Trausch-Azar, J.S. and Ilagan, M.X.G. and Benhamou, D. and Dittmar, G. and Kopan, R. and Birchmeier, W. and Schwartz, A.L. and Orian, A.
Cell Reports 16 (12): 3388-3400. 20 September 2016

Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A. and Cohen, I. and Popp, O. and Dittmar, G. and Reiss, Y. and Sommer, T. and Ravid, T. and Jarosch, E.
Molecular Cell 63 (5): 827-839. 1 September 2016

Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.
Yilmaz, Z.B. and Kofahl, B. and Beaudette, P. and Baum, K. and Ipenberg, I. and Weih, F. and Wolf, J. and Dittmar, G. and Scheidereit, C.
Cell Reports 9 (5): 1756-1769. 11 December 2014

Doerken, Bernd (MDC/ECRC)

Leukemia.
Bargou, R. and Ludwig, W.D.
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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
Bargou, R.C. and Emmerich, F. and Krappmann, D. and Bommert, K. and Mapara, M.Y. and Arnold, W. and Royer, H.D. and Grinstein, E. and Greiner, A. and Scheidereit, C. and Doerken, B.
Journal of Clinical Investigation 100 (12): 2961-2969. 15 December 1997

Characterization of a novel Hodgkin cell-line, HD-MyZ, HD-Myr, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.
Bargou, R.C. and Mapara, M.Y. and Zugck, C. and Daniel, P.T. and Pawlita, M. and Doehner, H. and Doerken, B.
Journal of Experimental Medicine 177 (5): 1257-1268. 1 May 1993

Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Arnold, W. and Daniel, P.T. and Mapara, M.Y. and Grinstein, E. and Royer, H.D. and Doerken, B.
Journal of Experimental Medicine 183 (3): 1205-1213. 1 March 1996

Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice.
Bargou, R.C. and Wagener, C. and Bommert, K. and Mapara, M.Y. and Daniel, P.T. and Arnold, W. and Dietel, M. and Guski, H. and Feller, A. and Royer, H.D. and Doerken, B.
Journal of Clinical Investigation 97 (11): 2651-2659. 1 June 1996

Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K. and Goergen, H. and Hitz, F. and Zijlstra, J.M. and Greil, R. and Markova, J. and Sasse, S. and Fuchs, M. and Topp, M.S. and Soekler, M. and Mathas, S. and Meissner, J. and Wilhelm, M. and Koch, P. and Lindemann, H.W. and Schalk, E. and Semrau, R. and Kriz, J. and Vieler, T. and Bentz, M. and Lange, E. and Mahlberg, R. and Hassler, A. and Vogelhuber, M. and Hahn, D. and Mezger, J. and Krause, S.W. and Skoetz, N. and Böll, B. and von Tresckow, B. and Diehl, V. and Hallek, M. and Borchmann, P. and Stein, H. and Eich, H. and Engert, A.
Lancet 385 (9976): 1418-1427. 11 April 2015

CD95 (APO-1/Fas) mutations in childhood T-lineage acute lymphoblastic leukemia.
Beltinger, C. and Kurz, E. and Boehler, T. and Schrappe, M. and Ludwig, W.D. and Debatin, K.M.
Blood 91 (10): 3943-3951. 15 May 1998

The reliability and specificity of c-kit for the diagnosis of acute myeloid leukemias and undifferentiated leukemias.
Bene, M.C. and Bernier, M. and Casasnovas, R.O. and Castoldi, G. and Knapp, W. and Lanza, F. and Ludwig, W.D. and Matutes, E. and Orfao, A. and Sperling, C. and van't Veer, M.B.
Blood 92 (2): 596-599. 15 July 1998

Need for safety goggles for endoscopy.
Benter, T. and Kluehs, L. and Teichgraeber, U.K.M. and Riechert, F. and Ludwig, W.D. and Doerken, B.
Endoscopy 35 (9): 803. 1 September 2003

Therapie eines Zenker'schen Divertikels [Therapy of Zenker's divertikulum].
Benter, T. and Kretzschmar, A. and Reich, G. and Papadopoulos, S. and Kluhs, L. and Ludwig, W.D. and Doerken, B.
Medizinische Klinik 97 (1): 44-45. January 2002

Anatomical variations in the internal jugular veins of cancer patients affecting central venous access. Anatomical variation of the internal jugular vein.
Benter, T. and Teichgraeber, U.K. and Kluehs, L. and Papadopoulos, S. and Koehne, C.H. and Felix, R. and Doerken, B.
Ultraschall in der Medizin 22 (1): 23-26. February 2001

Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia.
Berenstein, R. and Blau, I.W. and Suckert, N. and Baldus, C. and Pezzutto, A. and Dörken, B. and Blau, O.
Journal of Experimental & Clinical Cancer Research 34 (1): 55. 22 May 2015

Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region.
Berenstein, R. and Blau, O. and Nogai, A. and Waechter, M. and Slonova, E. and Schmidt-Hieber, M. and Kunitz, A. and Pezzutto, A. and Doerken, B. and Blau, I.W.
BMC Cancer 15 (1): 68. 18 February 2015

Multiple myeloma cells modify VEGF/IL-6 levels and osteogenic potential of bone marrow stromal cells via Notch/miR-223.
Berenstein, R. and Nogai, A. and Waechter, M. and Blau, O. and Kuehnel, A. and Schmidt-Hieber, M. and Kunitz, A. and Pezzutto, A. and Dörken, B. and Blau, I.W.
Molecular Carcinogenesis 55 (12): 1927-1939. December 2016

YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification.
Bergmann, S. and Royer-Pokora, B. and Fietze, E. and Juerchott, K. and Hildebrandt, B. and Trost, D. and Leenders, F. and Claude, J.C. and Theuring, F. and Bargou, R. and Dietel, M. and Royer, H.D.
Cancer Research 65 (10): 4078-4087. 16 May 2005

Clinical features and outcome of children with first marrow relapse of acute lymphoblastic leukemia expressing BCR-ABL fusion transcripts.
Beyermann, B. and Agthe, A.G. and Adams, H.P. and Seeger, K. and Linderkamp, C. and Goetze, G. and Ludwig, W.D. and Henze, G.
Blood 87 (4): 1532-1538. 15 February 1996

Lebendvakzine zur Behandlung von Tumorerkrankungen [Live vaccine for the treatment of tumour diseases].
T. Blankenstein, S. Cayeux.
EP0777499A1 ; EP0777499B1 ; WO9605866A2 ; WO9605866A3 ; US6,039,941. 11 June 1997

Cytolysis of leukemic B-cells by T-cells activated via 2 bispecific antibodies.
Bohlen, H. and Manzke, O. and Patel, B. and Moldenhauer, G. and Doerken, B. and von Fliedner, V. and Diehl, V. and Tesch, H.
Cancer Research 53 (18): 4310-4314. 15 September 1993

Treatment of brain metastases in patients with testicular cancer.
Bokemeyer, C. and Nowak, P. and Haupt, A. and Metzner, B. and Koehne, H. and Hartmann, J.T. and Kanz, L. and Schmoll, H.J.
Journal of Clinical Oncology 15 (4): 1449-1454. April 1997

Eight cycles of escalated-dose BEACOPP compared with four cycles of escalated-dose BEACOPP followed by four cycles of baseline-dose BEACOPP with or without radiotherapy in patients with advanced-stage Hodgkin's lymphoma: final analysis of the HD12 trial of the German Hodgkin study group.
Borchmann, P. and Haverkamp, H. and Diehl, V. and Cerny, T. and Markova, J. and Ho, A.D. and Eich, H.T. and Mueller-Hermelink, H.K. and Kanz, L. and Greil, R. and Rank, A. and Paulus, U. and Smardova, L. and Huber, C. and Doerken, B. and Nerl, C. and Krause, S.W. and Mueller, R.P. and Fuchs, M. and Engert, A.
Journal of Clinical Oncology 29 (32): 4234-4342. 10 November 2011

Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M. and Lee, S. and Loddenkemper, C. and Rudolph, C. and Peters, A.H. and Schlegelberger, B. and Stein, H. and Doerken, B. and Jenuwein, T. and Schmitt, C.A.
Nature 436 (7051): 660-665. 4 August 2005

Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.
Breit, T.M. and Mol, E.J. and Wolvers-Tettero, I.L. and Ludwig, W.D. and van Wering, E.R. and van Dongen, J.J.
Journal of Experimental Medicine 177 (4): 965-977. 1 April 1993

Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line - cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.
Brockstedt, E. and Rickers, A. and Kostka, S. and Laubersheimer, A. and Doerken, B. and Wittmann-Liebold, B. and Bommert, K. and Otto, A.
Journal of Biological Chemistry 273 (43): 28057-28064. 23 October 1998

6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by sequential HAM in adult patients at all ages with de novo acute myeloid leukemia (AML): a randomized trial of the German AML Cooperative Group.
Buechner, T. and Hiddemann, W. and Berdel, W.E. and Woermann, B. and Schoch, C. and Fonatsch, C. and Loeffler, H. and Haferlach, T. and Ludwig, W.D. and Maschmeyer, G. and Staib, P. and Aul, C. and Grueneisen, A. and Lengfelder, E. and Frickhofen, N. and Kern, W. and Serve, H.L. and Mesters, R.M. and Sauerland, M.C. and Heinecke, A.
Journal of Clinical Oncology 21 : 4496-4504. 15 December 2003

The receptor tyrosine kinase p185HER2 is expressed on a subset of B-lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia.
Buehring, H.J. and Sures, I. and Jallal, B. and Weiss, F.U. and Busch, F.W. and Ludwig, W.D. and Handgretinger, R. and Waller, H.D. and Ullrich, A.
Blood 86 (5): 1916-1923. 1 September 1995

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P. and Sasaki, Y. and Godinho, S.A. and Pellerin, A. and Köchert, K. and Sleckman, B.P. and de Alboran, I.M. and Janz, M. and Rodig, S. and Rajewsky, K.
Nature Immunology 13 (11): 1092-1100. November 2012

In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine.
Cayeux, S. and Bukarica, B. and Buschow, C. and Charo, J. and Bunse, M. and Doerken, B. and Blankenstein, T.
Gene Therapy 14 (20): 1481-1491. October 2007

STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
Chatterjee, M. and Jain, S. and Stuehmer, T. and Andrulis, M. and Ungethuem, U. and Kuban, R.J. and Lorentz, H. and Bommert, K. and Topp, M. and Kramer, D. and Mueller-Hermelink, H. K. and Einsele, H. and Greiner, A. and Bargou, R.C.
Blood 109 (2): 720-728. 15 January 2007

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells.
Chatterjee, M. and Stuehmer, T. and Herrmann, P. and Bommert, K. and Doerken, B. and Bargou, R.C.
Blood 104 (12): 3712-3721. 1 January 2004

Rituximab in the management of post-transplantation lymphoproliferative disorder after solid organ transplantation: proceed with caution.
Choquet, S. and Oertel, S. and Leblond, V. and Riess, H. and Varoqueaux, N. and Doerken, B. and Trappe, R.
Annals of Hematology 86 (8): 599-607. August 2007

Role of cranial radiotherapy for childhood T-cell acute lymphobalstic leukemia with high WBC count and good response to prednisone.
Conter, V. and Schrappe, M. and Arico, M. and Reiter, A. and Rizzari, C. and Doerdelmann, M. and Valsecchi, M.G. and Zimmermann, M. and Ludwig, W.D. and Basso, G. and Masera, G. and Riehm, H.
Journal of Clinical Oncology 15 (8): 2786-2791. August 1997

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.
Corral, J. and Forster, A. and Thompson, S. and Lampert, F. and Kaneko, Y. and Slater, R. and Kroes, W.G. and van der Schoot, C.E. and Ludwig, W.D. and Karpas, A. and Pocock, C. and Cotter, F. and Rabitts, T.H.
Proceedings of the National Academy of Sciences of the United States of America 90 (18): 8538-8542. 15 September 1993

Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Creutzig, U. and Harbott, J. and Sperling, C. and Ritter, J. and Zimmermann, M. and Loeffler, H. and Riehm, H. and Schellong, G. and Ludwig, W.D.
Blood 86 (8): 3097-3108. 1 October 1995

Grundlagen der molekularen Diagnostik und Therapie maligner Tumoren [Basics of molecular diagnostics and therapy of malignant tumors].
Daniel, P.T. and Doerken, B.
Internist 46 (8): 835-846. 12 July 2005

Immunotherapy of B-cell lymphoma with CD3x19 bispecific antibodies: costimulation via CD28 prevents "Veto" apoptosis of antibody-targeted cytotoxic T cells.
Daniel, P.T. and Kroidl, A. and Kopp, J. and Sturm, I. and Moldenhauer, G. and Doerken, B. and Pezzutto, A.
Blood 92 (12): 4750-4757. 15 December 1998

Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis.
Daniel, P.T. and Kroidl, A. and Cayeux, S. and Bargou, R.C. and Blankenstein, T. and Doerken, B.
Journal of Immunology 159 (8): 3808-3815. 15 October 1997

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E. and Herzog, S. and Labi, V. and Yasuda, T. and Köchert, K. and Janz, M. and Villunger, A. and Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5065-5070. 3 May 2016

Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkins disease.
Diehl, V. and Franklin, J. and Pfreundschuh, M. and Lathan, B. and Paulus, U. and Hasenclever, D. and Tesch, H. and Herrmann, R. and Doerken, B. and Mueller-Hermelink, H.K. and Duehmke, E. and Loeffler, M.
New England Journal of Medicine 348 (24): 2386-2395. 12 June 2003

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
Ding, Q. and Xia, W. and Liu, J.C. and Yang, J.Y. and Lee, D.F. and Xia, J. and Bartholomeusz, G. and Li, Y. and Pan, Y. and Li, Z. and Bargou, R.C. and Qin, J. and Lai, C.C. and Tsai, F.J. and Tsai, C.H. and Hung, M.C.
Molecular Cell 19 : 159-170. 1 January 2005

MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis.
Dreyling, M.H. and Schrader, K. and Fonatsch, C. and Schlegelberger, B. and Haase, D. and Schoch, C. and Ludwig, W.D. and Loeffler, H. and Buechner, T. and Wormann, B. and Hiddemann, W. and Bohlander, S.K.
Blood 91 (12): 4662-4667. 15 June 1998

HCMV-encoded chemokine receptor US28 employs multiple routes for internalization.
Droese, J. and Mokros, T. and Hermosilla, R. and Schuelein, R. and Lipp, M. and Hoepken, U.E. and Rehm, A.
Biochemical and Biophysical Research Communications 322 (1): 42-49. 10 September 2004

CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma.
Däbritz, J.H.M. and Yu, Y. and Milanovic, M. and Schönlein, M. and Rosenfeldt, M.T. and Dörr, J.R. and Kaufmann, A.M. and Dörken, B. and Schmitt, C.A.
Molecular Cancer Therapeutics 15 (5): 1074-1081. May 2016

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr, J.R. and Yu, Y. and Milanovic, M. and Beuster, G. and Zasada, C. and Däbritz, J.H.M. and Lisec, J. and Lenze, D. and Gerhardt, A. and Schleicher, K. and Kratzat, S. and Purfürst, B. and Walenta, S. and Mueller-Klieser, W. and Gräler, M. and Hummel, M. and Keller, U. and Buck, A.K. and Dörken, B. and Willmitzer, L. and Reimann, M. and Kempa, S. and Lee, S. and Schmitt, C.A.
Nature 501 (7467): 421-425. 19 September 2013

Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial.
Eich, H.T. and Diehl, V. and Goergens, H. and Pabst, T. and Markova, J. and Debus, J. and Ho, A. and Doerken, B. and Rank, A. and Grosu, A.L. and Wiegel, T. and Karstens, J.H. and Greil, R. and Willich, N. and Schmidberger, H. and Doehner, H. and Borchmann, P. and Mueller-Hermelink, H.K. and Mueller, R.P. and Engert, A.
Journal of Clinical Oncology 28 (27): 4199-4206. 20 September 2010

IkappaBalpha is required for marginal zone B cell lineage development.
Ellinghaus, U. and Rupec, R.A. and Pabst, O. and Ignatius, R. and Foerster, R. and Doerken, B. and Jundt, F.
European Journal of Immunology 38 (8): 2096-2105. August 2008

Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells.
Emmerich, F. and Theurich, S. and Hummel, M. and Haeffker, A. and Vry, M.S. and Doehner, K. and Bommert, K. and Stein, H. and Doerken, B.
Journal of Pathology 201 (3): 413-420. November 2003

The Golgi protein RCAS1 controls cell surface expression of tumor-associated O-linked glycan antigens.
Engelsberg, A. and Hermosilla, R. and Karsten, U. and Schuelein, R. and Doerken, B. and Rehm, A.
Journal of Biological Chemistry 278 (25): 22998-23007. 1 January 2003

Escalated-dose BEACOPP in the treatment of patients with advanced-stage Hodgkin's lymphoma: 10 years of follow-up of the GHSG HD9 study.
Engert, A. and Diehl, V. and Franklin, J. and Lohri, A. and Doerken, B. and Ludwig, W.D. and Koch, P. and Haenel, M. and Pfreundschuh, M. and Wilhelm, M. and Truemper, L. and Aulitzky, W.E. and Bentz, M. and Rummel, M. and Sezer, O. and Mueller-Hermelink, H.K. and Hasenclever, D. and Loeffler, M.
Journal of Clinical Oncology 27 (27): 4548-4554. 20 September 2009

Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.
Engert, A. and Haverkamp, H. and Kobe, C. and Markova, J. and Renner, C. and Ho, A. and Zijlstra, J. and Kral, Z. and Fuchs, M. and Hallek, M. and Kanz, L. and Doehner, H. and Doerken, B. and Engel, N. and Topp, M. and Klutmann, S. and Amthauer, H. and Bockisch, A. and Kluge, R. and Kratochwil, C. and Schober, O. and Greil, R. and Andreesen, R. and Kneba, M. and Pfreundschuh, M. and Stein, H. and Eich, H.T. and Mueller, R.P. and Dietlein, M. and Borchmann, P. and Diehl, V.
Lancet 379 (9828): 1791-1799. 12 May 2012

Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.
Engert, A. and Pluetschow, A. and Eich, H.T. and Lohri, A. and Doerken, B. and Borchmann, P. and Berger, B. and Greil, R. and Willborn, K.C. and Wilhelm, M. and Debus, J. and Eble, M.J. and Soekler, M. and Ho, A. and Rank, A. and Ganser, A. and Truemper, L. and Bokemeyer, C. and Kirchner, H. and Schubert, J. and Kral, Z. and Fuchs, M. and Mueller-Hermelink, H.K. and Mueller, R.P. and Diehl, V.
New England Journal of Medicine 363 (7): 640-652. 12 August 2010

Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli, U.M. and Ullrich, K. and Stuehmer, T. and Holien, T. and Koechert, K. and Holt, R.U. and Bruland, O. and Chatterjee, M. and Nogai, H. and Lenz, G. and Shaughnessy, J.D. and Mathas, S. and Sundan, A. and Bargou, R.C. and Doerken, B. and Borset, M. and Janz, M.
Oncogene 30 (28): 3198-3206. 14 July 2011

Long-lasting remission of pulmonary metastases of renal cell cancer under IFN-beta therapy in a patient with multiple sclerosis.
Floercken, A. and Denecke, T. and Kretzschmar, A. and Gollasch, H. and Reich, G. and Westermann, J.
Onkologie 29 : 382-384. September 2006

Severe thrombocytopenia in a patient with metastatic renal cell carcinoma.
Floercken, A. and Loew, A. and Koch, M. and Gebauer, B. and Doerken, B. and Riess, H.
Onkologie 32 (11): 670-672. November 2009

Hepatic arterial infusion chemotherapy for liver metastases from gastric cancer: an analysis in western patients.
Floercken, A. and Schaefer, C. and Bichev, D. and Breithaupt, K. and Dogan, Y. and Schumacher, G. and Gebauer, B. and Riess, H. and Doerken, B. and Thuss-Patience, P.C.
Tumori 97 (1): 19-24. January 2011

DC generation from peripheral blood mononuclear cells in patients with chronic myeloid leukemia: Influence of interferons on DC yield and functional properties.
Floercken, A. and Kopp, J. and Kölsch, U. and Meisel, C. and Dörken, B. and Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 12 (5): 1117-1123. 3 May 2016

Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken, A. and Grau, M. and Wolf, A. and Weilemann, A. and Kopp, J. and Dörken, B. and Blankenstein, T. and Pezzutto, A. and Lenz, P. and Lenz, G. and Westermann, J.
International Journal of Cancer 136 (8): 1814-1826. 15 April 2015

Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study.
Flörcken, A. and Kopp, J. and van Lessen, A. and Movassaghi, K. and Takvorian, A. and Jöhrens, K. and Möbs, M. and Schönemann, C. and Sawitzki, B. and Egerer, K. and Dörken, B. and Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9 (7): 1217-1227. 1 June 2013

Myeloid-derived suppressor cells in human peripheral blood: optimized quantification in healthy donors and patients with metastatic renal cell carcinoma.
Flörcken, A. and Takvorian, A. and Singh, A. and Gerhardt, A. and Ostendorf, B.N. and Dörken, B. and Pezzutto, A. and Westermann, J.
Immunology Letters 168 (2): 260-267. December 2015

Anti-leukemia T cells in AML: TNF-α(+) CD8(+) T cells may escape detection and possibly reflect a stage of functional impairment.
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Human Vaccines & Immunotherapeutics 9 (7): 1200-1204. 1 June 2013

New insights into the biology of molecular subtypes of diffuse large B-cell lymphoma and Burkitt lymphoma.
Frick, M. and Doerken, B. and Lenz, G.
Best Practice and Research Clinical Haematology 25 (1): 3-12. March 2012

The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.
Fuchs, U. and Rehkamp, G. and Haas, O.A. and Slany, R. and Konig, M. and Bojesen, S. and Bohle, R.M. and Damm-Welk, C. and Ludwig, W.D. and Harbott, J. and Borkhardt, A.
Proceedings of the National Academy of Sciences of the United States of America 98 (15): 8756-8761. 17 July 2001

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
Gillissen, B. and Essmann, F. and Graupner, V. and Staerck, L. and Radetzki, S. and Doerken, B. and Schulze-Osthoff, K. and Daniel, P.T.
EMBO Journal 22 (14): 3580-3590. 15 July 2003

Recombinant human erythropoietin, epoetin beta, in patients with relapsed lymphoma treated with aggressive sequential salvage chemotherapy - results of a randomized trial.
Glossmann, J.P. and Engert, A. and Wassmer, G. and Flechtner, H. and Ko, Y. and Rudolph, C. and Metzner, B. and Doerken, B. and Wiedenmann, S. and Diehl, V. and Josting, A.
Annals of Hematology 82 (8): 469-475. 1 August 2003

Prognostic value of multimarker analysis in stage III colorectal cancer: one step forward towards an individualized therapy decision.
Grabowski, P. and Maaser, K. and Hanski, C. and Stein, H. and Sturm, I. and Hopfenmueller, W. and Doerken, B. and Buhr, H.J. and Zeitz, M. and Scheruebl, H.
Onkologie 28 (8-9): 399-403. 1 August 2005

T-cell-mediated lysis of B cells induced by a CD19xCD3 bispecific single-chain antibody is perforin dependent and death receptor independent.
Gruen, M. and Bommert, K. and Bargou, R.C.
Cancer Immunology Immunotherapy 53 (7): 625-632. 1 January 2004

Disruption of cell death signaling in cancer: impact on disease prognosis and response to therapy.
Guener, D. and Belka, C. and Daniel, P.T.
Current Medicinal Chemistry Anti-Cancer Agents 3 (5): 319-326. 1 September 2003

Morphologic dysplasia in de novo acute myeloid leukemia (AML) is related to unfavorable cytogenetics but has no independent prognostic relevance under the conditions of intensive induction therapy: results of a multiparameter analysis from the German AML Cooperative Group studies.
Haferlach, T. and Schoch, C. and Loeffler, H. and Gassmann, W. and Kern, W. and Schnittger, S. and Fonatsch, C. and Ludwig, W.D. and Wuchter, C. and Schlegelberger, B. and Staib, P. and Reichle, A. and Kubica, U. and Eimermacher, H. and Balleisen, L. and Grueneisen, A. and Haase, D. and Aul, C. and Karow, J. and Lengfelder, E. and Woermann, B. and Heinecke, A. and Sauerland, M.C. and Buechner, T. and Hiddemann, W.
Journal of Clinical Oncology 21 : 256-265. 15 January 2003

Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines.
Hailfinger, S. and Nogai, H. and Pelzer, C. and Jaworski, M. and Cabalzar, K. and Charton, J.E. and Guzzardi, M. and Decaillet, C. and Grau, M. and Doerken, B. and Lenz, P. and Lenz, G. and Thome, M.
Proceedings of the National Academy of Sciences of the United States of America 108 (35): 14596-14601. 30 August 2011

Cellular senescence predicts treatment outcome in metastasised colorectal cancer.
Haugstetter, A.M. and Loddenkemper, C. and Lenze, D. and Groene, J. and Standfuss, C. and Petersen, I. and Doerken, B. and Schmitt, C.A.
British Journal of Cancer 103 (4): 505-509. 10 August 2010

An individual patient-data comparison of combined modality therapy and ABVD alone for patients with limited-stage Hodgkin lymphoma.
Hay, A.E. and Klimm, B. and Chen, B.E. and Goergen, H. and Shepherd, L.E. and Fuchs, M. and Gospodarowicz, M.K. and Borchmann, P. and Connors, J.M. and Markova, J. and Crump, M. and Lohri, A. and Winter, J.N. and Doerken, B. and Pearcey, R.G. and Diehl, V. and Horning, S.J. and Eich, H.T. and Engert, A. and Meyer, R.M.
Annals of Oncology 24 (12): 3065-3069. December 2013

Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
Heinig, K. and Gätjen, M. and Grau, M. and Stache, V. and Anagnostopoulos, I. and Gerlach, K. and Niesner, R.A. and Cseresnyes, Z. and Hauser, A.E. and Lenz, P. and Hehlgans, T. and Brink, R. and Westermann, J. and Dörken, B. and Lipp, M. and Lenz, G. and Rehm, A. and Höpken, U.E.
Cancer Discovery 4 : 1448-1465. December 2014

Cytogenetic risk grouping by the monosomal karyotype classification is superior in predicting the outcome of acute myeloid leukemia undergoing allogeneic stem cell transplantation in complete remission.
Hemmati, P.G. and Schulze-Luckow, A. and Terwey, T.H. and le Coutre, P. and Vuong, L.G. and Doerken, B. and Arnold, R.
European Journal of Haematology 92 (2): 102-110. February 2014

Reduced intensity conditioning prior to allogeneic stem cell transplantation in first complete remission is effective in patients with acute myeloid leukemia and an intermediate-risk karyotype.
Hemmati, P.G. and Terwey, T.H. and Massenkeil, G. and le Coutre, P. and Vuong, L.G. and Neuburger, S. and Doerken, B. and Arnold, R.
International Journal of Hematology 91 (3): 436-445. April 2010

Allogeneic stem cell transplantation for refractory acute myeloid leukemia: a single center analysis of long-term outcome.
Hemmati, P.G. and Terwey, T.H. and Na, I.K. and Jehn, C.F. and le Coutre, P. and Vuong, L.G. and Doerken, B. and Arnold, R.
European Journal of Haematology 95 (6): 498-506. December 2015

A modified EBMT risk score predicts the outcome of patients with acute myeloid leukemia receiving allogeneic stem cell transplants.
Hemmati, P.G. and Terwey, T.H. and le Coutre, P. and Vuong, L.G. and Massenkeil, G. and Doerken, B. and Arnold, R.
European Journal of Haematology 86 (4): 305-316. April 2011

Impact of early remission by induction therapy on allogeneic stem cell transplantation for acute myeloid leukemia with an intermediate risk karyotype in first complete remission.
Hemmati, P.G. and Terwey, T.H. and Na, I.K. and le Coutre, P. and Jehn, C.F. and Vuong, L.G. and Dörken, B. and Arnold, R.
European Journal of Haematology 94 (5): 431-438. May 2015

Intraoperative fresh-frozen plasma versus human albumin in craniofacial surgery - a pilot study comparing coagulation profiles in infants younger than 12 months.
Hildebrandt, B. and Machotta, A. and Riess, H. and Kerner, S. and Ahlers, O. and Haberl, H. and Doerken, B. and Kerner, T.
Thrombosis and Haemostasis 98 (1): 172-7. July 2007

Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: A phase II-study and historical comparison with the surgical approach.
Hildebrandt, B. and Pech, M. and Nicolaou, A. and Langrehr, J.M. and Kurcz, J. and Bartels, B. and Miersch, A. and Felix, R. and Neuhaus, P. and Riess, H. and Doerken, B. and Ricke, J.
BMC Cancer 7 : 69. 24 April 2007

Adjuvant chemotherapy with folinic acid and 5-fluorouracil in patients with locally advanced rectal cancer previously treated by preoperative radiochemotherapy and curative tumor resection.
Hildebrandt, B. and Rau, B. and Loeffel, J. and Wust, P. and Nicolaou, A. and Gellermann, J. and Le Coutre, P. and Neuhaus, P. and Felix, R. and Wernecke, K.D. and Doerken, B. and Riess, H.
International Journal of Colorectal Disease 21 (6): 582-589. September 2006

Clinical research and industrial sponsoring: avenues towards transparency and credibility.
Hildebrandt, M. and Ludwig, W.D.
Onkologie 26 : 529-534. 1 December 2003

Nuclear factor κB-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M. and Lemke, P. and Anagnostopoulos, I. and Hacker, C. and Krappmann, D. and Mathas, S. and Doerken, B. and Zenke, M. and Stein, H. and Scheidereit, C.
Journal of Experimental Medicine 196 (5): 605-617. 2 September 2002

Expression of a hypoglycosylated form of CD86 (B7-2) on human T cells with altered binding properties to CD28 and CTLA-4.
Hoellsberg, P. and Scholz, C. and Anderson, D.E. and Greenfield, E.A. and Kuchroo, V.K. and Freeman, G.J. and Hafler, D.A.
Journal of Immunology 159 (10): 4799-4805. 15 November 1997

A novel recombinant bispecific single-chain antibody, bscWue-1 x CD3, induces T-cell-mediated cytotoxicity towards human multiple myeloma cells.
Hoenemann, D. and Kufer, P. and Rimpler, M.M. and Chatterjee, M. and Friedl, S. and Riecher, F. and Bommert, K. and Doerken, B. and Bargou, R.C.
Leukemia 18 (3): 636-644. 1 January 2004

The ratio between dendritic cells and T cells determines the outcome of their encounter: Proliferation versus deletion.
Hoepken, U.E. and Lehmann, I. and Droese, J. and Lipp, M. and Schueler, T. and Rehm, A.
European Journal of Immunology 35 (10): 2851-2863. 23 September 2005

Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs.
Hoepken, U.E. and Rehm, A.
Journal of Molecular Medicine 90 (11): 1237-1245. November 2012

CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
Hoepken, U.E. and Wengner, A.M. and Loddenkemper, C. and Stein, H. and Heimesaat, M.M. and Rehm, A. and Lipp, M.
Blood 109 (3): 886-895. 1 February 2007

Serial killing of tumor cells by cytotoxic T cells redirected with a CD19-/CD3-bispecific single-chain antibody construct.
Hoffmann, P. and Hofmeister, R. and Brischwein, K. and Brandl, C. and Crommer, S. and Bargou, R. and Itin, C. and Prang, N. and Baeuerle, P.A.
International Journal of Cancer 115 : 98-104. 1 January 2005

A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.
Hofgaard, P.O. and Jodal, H.C. and Bommert, K. and Huard, B. and Caers, J. and Carlsen, H. and Schwarzer, R. and Schuenemann, N. and Jundt, F. and Lindeberg, M.M. and Bogen, B.
PLoS ONE 7 (12): e51892. 20 December 2012

Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor.
Holdhoff, M. and Kreuzer, K.A. and Appelt, C. and Scholz, R. and Na, I.K. and Hildebrandt, B. and Riess, H. and Jordan, A. and Schmidt, C.A. and Van Etten, R.A. and Doerken, B. and LeCoutre, P.
Blood Cells Molecules and Diseases 34 (2): 181-185. 1 March 2005

Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission.
Janssen, J.W. and Ludwig, W.D. and Borkhardt, A. and Spadinger, U. and Rieder, H. and Fonatsch, C. and Hossfeld, D.K. and Harbott, J. and Schulz, A.S. and Repp, R. and Sykora, K.W. and Hoelzer, D. and Bartram, C.R.
Blood 84 (11): 3835-3842. 1 December 1994

Reprogramming of B lymphoid cells in human lymphoma pathogenesis.
Janz, M. and Doerken, B. and Mathas, S.
Cell Cycle 5 (10): 1057-1061. 15 May 2006

Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
Janz, M. and Hummel, M. and Truss, M. and Wollert-Wulf, B. and Mathas, S. and Joehrens, K. and Hagemeier, C. and Bommert, K. and Stein, H. and Doerken, B. and Bargou, R.C.
Blood 107 (6): 2536-2539. 15 March 2006

The pathogenesis of classical Hodgkin's lymphoma: what can we learn from analyses of genomic alterations in Hodgkin and Reed-Sternberg cells?
Janz, M. and Mathas, S.
Haematologica 93 (9): 1292-1295. September 2008

Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells.
Janz, M. and Stuehmer, T. and Vassilev, L.T. and Bargou, R.C.
Leukemia 21 (4): 772-779. April 2007

Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H. and Kase, J. and Doerr, J.R. and Milanovic, M. and Lenze, D. and Grau, M. and Beuster, G. and Ji, S. and Reimann, M. and Lenz, P. and Hummel, M. and Doerken, B. and Lenz, G. and Scheidereit, C. and Schmitt, C.A. and Lee, S.
Genes & Development 25 (20): 2137-2146. 15 October 2011

Morphologie gastrointestinaler Stromatumoren im fortgeschrittenen Stadium der Erkrankung: Ausgangsbefunde vor Chemotherapie mit Imatinib [Morphology of gastrointestinal stromal tumors in advanced stages of the disease: baseline findings before chemotherapy with imatinib].
Jost, D. and Stroszczynski, C. and Chmelik, P. and Gaffke, G. and Schlecht, I. and Pink, D. and Reichardt, P. and Schneider, U. and Hohenberger, P. and Felix, R.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 175 : 791-798. 1 June 2003

Cologne high-dose sequential chemotherapy in relapsed and refractory Hodgkin lymphoma: results of a large multicenter study of the German Hodgkin Lymphoma Study Group (GHSG).
Josting, A. and Rudolph, C. and Mapara, M. and Glossmann, J.P. and Sieniawski, M. and Sieber, M. and Kirchner, H.H. and Doerken, B. and Hossfeld, D.K. and Kisro, J. and Metzner, B. and Berdel, W.E. and Diehl, V. and Engert, A.
Annals of Oncology 16 : 116-123. 1 January 2005

High-dose sequential chemotherapy followed by autologous stem cell transplantation in relapsed and refractory aggressive non-Hodgkin's lymphoma: results of a multicenter phase II study.
Josting, A. and Sieniawski, M. and Glossmann, J.P. and Staak, O. and Nogova, L. and Peters, N. and Mapara, M. and Doerken, B. and Ko, Y. and Metzner, B. and Kisro, J. and Diehl, V. and Engert, A.
Annals of Oncology 16 : 1359-1365. 1 January 2005

Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma.
Jundt, F. and Acikgoez, O. and Kwon, S.H. and Schwarzer, R. and Anagnostopoulos, I. and Wiesner, B. and Mathas, S. and Hummel, M. and Stein, H. and Reichardt, H.M. and Doerken, B.
Leukemia 22 (8): 1587-1594. August 2008

Trimethoprim-sulfamethoxazole exacerbates posthypoxic action myoclonus in a patient with suspicion of Pneumocystis jiroveci infection.
Jundt, F. and Lempert, T. and Doerken, B. and Pezzutto, A.
Infection 32 (3): 176-178. 1 June 2004

A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F. and Raetzel, N. and Mueller, C. and Calkhoven, C.F. and Kley, K. and Mathas, S. and Lietz, A. and Leutz, A. and Doerken, B.
Blood 106 : 1801-1807. 1 January 2005

Jagged1-induced notch signaling drives proliferation of multiple myeloma cells.
Jundt, F. and Schulze-Proebsting, K. and Anagnostopoulos, I. and Muehlinghaus, G. and Chatterjee, M. and Mathas, S. and Bargou, R.C. and Manz, R. and Stein, H. and Doerken, B.
Blood 103 (9): 3511-3515. 1 January 2004

Notch signaling in leukemias and lymphomas.
Jundt, F. and Schwarzer, R. and Doerken, B.
Current Molecular Medicine 8 (1): 51-59. February 2008

JAK2 V617F allele burden quantified by real time quantitative polymerase chain reaction and competitive polymerase chain reaction in patients with chronic myeloproliferative neoplasia.
Kaeda, J. and Bonamino, M. and Ayres-Silva, J. and Solza, C. and Ringel, F. and Blau, O. and Daumas, A. and Oberender, C. and Doerken, B. and Le Coutre, P. and Zalcberg, I.
Leukemia & Lymphoma 55 (1): 128-135. January 2014

Differential expression of SHP-1 in chronic myeloid leukemia.
Kaeda, J. and Neuman, D. and Bonecker, S. and Mills, K. and Oberender, C. and Amini, L. and Ringel, F. and Serra, A. and Schwarz, M. and Doerken, B. and Zalcberg, I. and Le Coutre, P.
Leukemia & Lymphoma 56 (5): 1547-1549. May 2015

Longitudinal study to assess the clinical significance of MSI2 expression in chronic myeloid keukemia patients.
Kaeda, J. and Ringel, F. and Oberender, C. and Gresse, M. and Amini, L. and Schwarz, M. and Doerken, B. and le Coutre, P.
Acta Haematologica 136 (1): 62-64. June 2016

Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.
Kaeda, J. and Ringel, F. and Oberender, C. and Mills, K. and Quintarelli, C. and Pane, F. and Koschmieder, S. and Slany, R. and Schwarzer, R. and Saglio, G. and Hemmati, P. and van Lessen, A. and Amini, L. and Greese, M. and Vagge, E. and Burmeister, T. and Serra, A. and Carson, A. and Schwarz, M. and Westermann, J. and Jundt, F. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 56 (7): 2105-2113. July 2015

Cellular senescence in cancer treatment: friend or foe?
Kahlem, P. and Doerken, B. and Schmitt, C.A.
Journal of Clinical Investigation 113 (2): 169-174. January 2004

Detection of minimal residual disease in unselected patients with acute myeloid leukemia using multiparameter flow cytometry for definition of leukemia-associated immunophenotypes and determination of their frequencies in normal bone marrow.
Kern, W. and Danhauser-Riedl, S. and Ratei, R. and Schnittger, S. and Schoch, C. and Kolb, H.J. and Ludwig, W.D. and Hiddemann, W. and Haferlach, T.
Haematologica 88 : 646-653. 1 June 2003

Correlation of protein expression and gene expression in acute leukemia.
Kern, W. and Kohlmann, A. and Wuchter, C. and Schnittger, S. and Schoch, C. and Mergenthaler, S. and Ratei, R. and Ludwig, W.D. and Hiddemann, W. and Haferlach, T.
Cytometry 55B : 29-36. 1 September 2003

Peripheral artery occlusive disease (PAOD) in chronic phase chronic myeloid leukemia patients treated with nilotinib or Imatinib.
Kim, T.D. and Rea, D. and Schwarz, M. and Grille, P. and Nicolini, F.E. and Rosti, G. and Levato, L. and Giles, F.J. and Dombret, H. and Mirault, T. and Labussiere, H. and Lindhorst, R. and Haverkamp, W. and Buschmann, I. and Doerken, B. and le Coutre, P.D.
Leukemia 27 (6): 1316-1321. 5 April 2013

Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D. and Schwarz, M. and Nogai, H. and Grille, P. and Westermann, J. and Ploeckinger, U. and Braun, D. and Schweizer, U. and Arnold, R. and Doerken, B. and le Coutre, P.
Thyroid 20 (11): 1209-1214. 9 November 2010

Clinical cardiac safety profile of nilotinib.
Kim, T.D. and le Coutre, P. and Schwarz, M. and Grille, P. and Levitin, M. and Fateh-Moghadam, S. and Giles, F.J. and Doerken, B. and Haverkamp, W. and Koehncke, C.
Haematologica 97 (6): 883-889. June 2012

Critical role of PI3K signaling for NF-κB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.
Kloo, B. and Nagel, D. and Pfeifer, M. and Grau, M. and Duewel, M. and Vincendeau, M. and Doerken, B. and Lenz, P. and Lenz, G. and Krappmann, D.
Proceedings of the National Academy of Sciences of the United States of America 108 (1): 272-277. 4 January 2011

Genauigkeit der sonographischen Milzgewichtsbestimmung am Lebenden im Vergleich zum pathologischen Korrelat [Accuracy of the sonographic determination of the splenic weight in comparison with the weight at autopsy].
Kluehs, L. and Teichgraeber, U.K. and Schneider, U. and Ludwig, W.D. and Doerken, B. and Benter, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 175 (4): 532-535. 1 April 2003

High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
Koecher