2026
Early gut-vascular barrier breakdown precedes colitis onset in murine models.
Abdou, Mariam Mohamed, Kreiß, Lucas, Schmid, Benjamin, Thoma, Oana-Maria, Krüger, René, Bénard, Alan, Müller, Tanja M., Knauss, Annkathrin, Gabel, Michael, González-Acera, Miguel, Lyu, Yanmin, Petter, Katja, Lindemann, Aylin, Saad, Mina Saad Aziz, Eichhorn, Philip, Becker, Christoph, Naschberger, Elisabeth, Zundler, Sebastian, Weigmann, Benno, Rath, Timo, Atreya, Raja, Kühl, Anja A., Trajanoski, Zlatko, Friedrich, Oliver, Waldner, Maximilian J., Neurath, Markus F., Herrmann, Martin, Schürmann, Sebastian, Britzen-Laurent, Nathalie and Stürzl, Michael
Cellular and molecular gastroenterology and hepatology 20
(9): 101795.
15 June 2026
Stable Hrd1 tetramers at the heart of the retrotranslocon in living cells.
Abel, Tim, Subramanya, Shubha 
ORCID: https://orcid.org/0009-0002-6976-575X, Liu, Brandon M. ORCID: https://orcid.org/0000-0002-2749-8182, Schütz, Anja ORCID: https://orcid.org/0000-0002-0606-2574, Lippincott-Schwartz, Jennifer, Neal, Sonya E. ORCID: https://orcid.org/0000-0002-9618-8428, Sommer, Thomas ORCID: https://orcid.org/0000-0001-9990-5202 and Obara, Christopher J. ORCID: https://orcid.org/0000-0003-1028-6076
bioRxiv
: 2026.06.16.732623.
17 June 2026
Flexibility of cell fates and functions across sex determination systems revealed by comparative single-cell analyses.
Acemel, Rafael D. ORCID: https://orcid.org/0000-0003-4120-0140, Tezak, Boris ORCID: https://orcid.org/0000-0002-2621-4272, Chung, Vicky Wai Yee, Hurtado, Alicia ORCID: https://orcid.org/0000-0001-6267-704X, Albertson, Scarlett, Weber, Ceri J. ORCID: https://orcid.org/0000-0001-8541-0110, Capel, Blanche ORCID: https://orcid.org/0000-0002-6587-0969 and Lupiáñez, Darío G. ORCID: https://orcid.org/0000-0002-3165-036X
bioRxiv
: 2026.01.29.701242.
30 January 2026
A non-viral CRISPR/Cas9 HDR platform for stable engineering of solid tumor models.
Afzal, Shoaib ORCID: https://orcid.org/0009-0009-5490-6098, Pilgram, Maximilian, Macos, Julia, Ohlendorf, Emily, Raab, Lena Olivia, Kath, Jonas, Glaser, Viktor, Nitulescu, Ana-Maria, van der Ven, Casper F.T., Lachiheb, Chahrazad, Stecklum, Maria, Drzeniek, Norman Michael ORCID: https://orcid.org/0000-0001-6562-2351, Anders, Kathleen ORCID: https://orcid.org/0000-0002-0429-200X, Wagner, Dimitrios Laurin, Kühn, Ralf ORCID: https://orcid.org/0000-0003-1694-9803, Künkele, Annette and Launspach, Michael ORCID: https://orcid.org/0000-0001-5337-5605
bioRxiv
: 2026.06.01.729035.
4 June 2026
Rapid and profound treatment response of difficult-to-treat rheumatoid arthritis to CD19 CAR T-cell therapy.
Albach, Fredrik N., Minopoulou, Ioanna, Wilhelm, Artur, Kleyer, Arnd, Wiebe, Edgar, Fleischmann, Anja, Engel, Klaus, Frick, Mareike, Damm, Frederik, Gogolok, Julia, Serve, Sebastian, Locher, Benjamin, Borie, Dominic, Phithak, Elpida, Hinkelmann, Lukas, Ohrndorf, Sarah, Casteleyn, Vincent, Biesen, Robert, Sattler, Arne, Dörner, Thomas, Drzeniek, Norman M., Alexander, Tobias, Zernicke, Jan, Unterwalder, Nadine, Movassaghi, Kamran, Hütter-Krönke, Marie Luise, Schrezenmeier, Eva ORCID: https://orcid.org/0000-0002-0016-7885, Schreiber, Adrian ORCID: https://orcid.org/0000-0003-1244-6379, Furth, Christian, Schett, Georg, Schneider, Udo, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Krönke, Gerhard, Penack, Olaf and Simon, David ORCID: https://orcid.org/0000-0001-8310-7820
EULAR Rheumatology Open
June 2026
Teclistamab for treatment-refractory autoimmune diseases: a multicentre case series.
Albach, Fredrik N. ORCID: https://orcid.org/0000-0002-2697-9080, Phithak, Elpida, Biesen, Robert ORCID: https://orcid.org/0000-0002-0434-7832, Kleyer, Arnd, Siegert, Elise, Minopoulou, Ioanna, Algharably, Engi, Casteleyn, Vincent, Beenken, Anne E., Schneider, Udo, Trezzini, Sofia, Rehm, Marie, Sattler, Arne, Sinzinger, Benedikt, Wiebe, Edgar, Unterwalder, Nadine, Scholz, Veronika, Staeck, Anja, Hütter-Krönke, Marie Luise, Buttgereit, Frank, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Krönke, Jan, Kötter, Ina, Kremer, Phillip, Exner, Tarik, Pecher, Ann-Christin, Kaudewitz, Dorothee, Sondergaard, Klaus, Troldborg, Anne, Henes, Jörg, Lorenz, Hanns-Martin, Haase, Isabell, Krusche, Martin, Krönke, Gerhard, Simon, David ORCID: https://orcid.org/0000-0001-8310-7820 and Alexander, Tobias ORCID: https://orcid.org/0000-0003-1193-0097
Annals of the Rheumatic Diseases
19 June 2026
(In Press)
CD19 CAR T cell therapy for treatment-refractory seropositive rheumatoid arthritis: a phase 1 trial.
Albach, Fredrik N. ORCID: https://orcid.org/0000-0002-2697-9080, Rehm, Marie C. ORCID: https://orcid.org/0000-0002-4196-7838, Hütter-Krönke, Marie Luise ORCID: https://orcid.org/0000-0002-4531-9889, Le, Thanh Hang ORCID: https://orcid.org/0009-0001-8020-354X, Giezen, Julia M. ORCID: https://orcid.org/0000-0003-1024-4028, Torgutalp, Murat, Sattler, Arne, Minopoulou, Ioanna, Biesen, Robert ORCID: https://orcid.org/0000-0002-0434-7832, Wiebe, Edgar, Casteleyn, Vincent, Witte, Thorben ORCID: https://orcid.org/0000-0003-3313-6759, Furth, Christian, Zernicke, Jan ORCID: https://orcid.org/0000-0002-5163-2177, Nuesch Germano, Melanie, Verhagen, Johan ORCID: https://orcid.org/0000-0001-8414-1342, Wilhelm, Artur, Dzamukova, Maria ORCID: https://orcid.org/0000-0002-2389-3222, Engel, Klaus, Schallenberg, Simon ORCID: https://orcid.org/0000-0002-7897-7116, Kannt, Aimo ORCID: https://orcid.org/0000-0002-5197-2286, Ziegler, Nicole, Fehringer, Michaela ORCID: https://orcid.org/0009-0002-1366-1628, Schneider, Udo, Unterwalder, Nadine, Beling, Mark, Pfeil, Alexander, Phithak, Elpida, Krusche, Martin, Penack, Olaf ORCID: https://orcid.org/0000-0003-4876-802X, Alexander, Tobias ORCID: https://orcid.org/0000-0003-1193-0097, Stenzel, Werner, Wuhrer, Manfred ORCID: https://orcid.org/0000-0002-0814-4995, Movassaghi, Kamran, Dörner, Thomas ORCID: https://orcid.org/0000-0002-6478-7725, Latz, Eicke, Vogl, Thomas ORCID: https://orcid.org/0000-0002-3892-1740, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Schett, Georg ORCID: https://orcid.org/0000-0001-8740-9615, Scherer, Hans Ulrich ORCID: https://orcid.org/0000-0002-5700-5617, Toes, Rene E.M. ORCID: https://orcid.org/0000-0002-9618-6414, Kleyer, Arnd, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Simon, David ORCID: https://orcid.org/0000-0001-8310-7820 and Krönke, Gerhard ORCID: https://orcid.org/0000-0002-7566-4325
Nature Medicine
27 August 2026
(In Press)
The regulatory interplay of the colorectal cancer biomarkers MACC1 and IER2 and its impact on metastatic cancer survival.
Alberto Vilchez, Miguel Enrique ORCID: https://orcid.org/0000-0002-6249-6932, Kortüm, Benedikt ORCID: https://orcid.org/0000-0003-3734-6665, Schöpe, Paul ORCID: https://orcid.org/0000-0002-5512-8832, Kyjacova, Lenka, Zincke, Fabian, Osterland, Marc ORCID: https://orcid.org/0000-0001-9133-9322, Walther, Wolfgang ORCID: https://orcid.org/0000-0003-2360-1370, Rau, Beate ORCID: https://orcid.org/0000-0001-5820-6907, Sleeman, Jonathan ORCID: https://orcid.org/0000-0003-1718-7687 and Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X
Biomolecules 16
(3): 398.
March 2026
Transcriptomic profiling reveals substrate- and shear stress_x0002_dependent maturation of human small intestinal epithelial cells.
Alzain, N., Almalla, A., Sandu, K., Gerbeth, L., Ziegler, J., Gutwein, C., Weidner, P. ORCID: https://orcid.org/0000-0003-2448-5981, Glauben, R., Weinhart, M. and Siegmund, B.
[Dataset]
22 April 2026
Transcriptomic profiling reveals substrate- and shear stress-dependent maturation of human small intestinal epithelial cells.
Alzain, Nadra, Almalla, Ahed, Sandu, Ketaki, Gerbeth, Lorenz, Ziegler, Jörn F., Gutwein, Catharina, Weidner, Patrick ORCID: https://orcid.org/0000-0003-2448-5981, Glauben, Rainer, Weinhart, Marie and Siegmund, Britta
Frontiers in Pharmacology 17
: 1706106.
1 May 2026
Probing 3-amino-2H-azaindazoles as allosteric inhibitors of the protein tyrosine phosphatase SHP2.
Amoussa, Machoud, Efrém, Nina-Louisa, Li, Feng, Guo, Ziqiong, Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Frank, Katrin Jana, Pach, Szymon, Wolf, Clemens Alexander, Bo, Feng, Lesina, Marina, Kintzel, Mika, Alsalim, Rana, Zeitz, Victoria, Csorba, Noémi, Radetzki, Silke ORCID: https://orcid.org/0000-0003-2688-2868, Keserű, György M., Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, Algül, Hana, Wolber, Gerhard, Li, Jia and Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330
ChemMedChem 21
(11): e70341.
15 June 2026
Heart failure therapy in patients with advanced cancer receiving specialized palliative care (EMPATICC trial).
Anker, Markus S. ORCID: https://orcid.org/0000-0002-4406-8555, Mahabadi, Amir A., Totzeck, Matthias, Tewes, Mitra, Shahzeb Khan, Muhammad, Mincu, Raluca I., Hendgen-Cotta, Ulrike B., Michel, Lars, Mathew, Baicy, Drescher, Ophelia, Schuler, Martin, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Rieger, Kathrin, Ahn, Johann, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Modest, Dominik P., Denecke, Corinna, Kretzler, Lucie, Ramer, Luisa V., Krug, Danara, Landmesser, Ulf, Lehmann, Lorenz, Frey, Norbert, Bercker, Sven, Laufs, Ulrich, Böhm, Michael, Mahfoud, Felix ORCID: https://orcid.org/0000-0002-4425-549X, Merkely, Bela, Diek, Monika, Butler, Javed, Veiser, Anja, Heise, Tim, Hellmich, Martin, Placzek, Marius, Friede, Tim ORCID: https://orcid.org/0000-0001-5347-7441, Anker, Stefan D. and Rassaf, Tienush
European Heart Journal 47
(9): 1034-1046.
1 March 2026
Lipid nanoparticle-based non-viral in situ gene editing of congenital ichthyosis-causing mutations in human skin models.
Apaydin, Dilem Ceren, Sadhnani, Gaurav ORCID: https://orcid.org/0009-0000-9803-410X, Carlaw, Tiffany, Renziehausen, Jan, Lizunova, Elena, Filor, Viviane, Hiller, Anna, Brumhard, Sophia, Halim, Vincent, Brüning, Ulrike ORCID: https://orcid.org/0000-0003-0112-4032, Bischof, Johannes, Marodin, Rafaela Horbach, Kurek, Daniel Z., Rhiel, Manuel, Ammann, Sandra, Cornu, Tatjana I., Cathomen, Toni, Sander, Leif Erik, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Kirwan, Jennifer ORCID: https://orcid.org/0000-0002-5423-1651, Koller, Ulrich, Gruber, Achim D., Bäumer, Wolfgang and Hedtrich, Sarah ORCID: https://orcid.org/0000-0001-6770-3657
Cell Stem Cell 33
(2): 233-252.e12.
5 February 2026
Supporting-like cells constitute an alternative steroidogenic lineage conserved in amniotes.
Barberá-Aura, Iván ORCID: https://orcid.org/0009-0007-6058-3796, Chung, Wai-Yee, Dujardin, Emilie ORCID: https://orcid.org/0000-0002-8189-8742, Hurtado, Alicia ORCID: https://orcid.org/0000-0001-6267-704X, Galmiche, Mathieu ORCID: https://orcid.org/0000-0001-5840-4786, Mayère, Chloé ORCID: https://orcid.org/0000-0002-9254-4886, Guy, Maëva ORCID: https://orcid.org/0009-0007-7802-5186, Mandon-Pépin, Béatrice ORCID: https://orcid.org/0000-0002-5424-0822, Franke, Vedran ORCID: https://orcid.org/0000-0003-3606-6792, Jaszczyszyn, Yan ORCID: https://orcid.org/0000-0002-2269-677X, Acemel, Rafael D. ORCID: https://orcid.org/0000-0003-4120-0140, Rudaz, Serge ORCID: https://orcid.org/0000-0002-4180-5417, Mckey, Jennifer ORCID: https://orcid.org/0000-0002-2640-1502, Nef, Serge ORCID: https://orcid.org/0000-0001-5462-0676, Pailhoux, Eric ORCID: https://orcid.org/0000-0001-8012-9143 and Lupiáñez, Darío G. ORCID: https://orcid.org/0000-0002-3165-036X
bioRxiv
: 2026.05.25.726204.
28 May 2026
Symbiotic yeasts of a bark beetle transform major tree defenses into beetle protectants.
Baños-Quintana, Ana Patricia ORCID: https://orcid.org/0000-0003-1286-7595, Santiago-Padilla, Leandro Manuel ORCID: https://orcid.org/0000-0002-0873-7205, Reichelt, Michael ORCID: https://orcid.org/0000-0002-6691-6500, Sun, Ruo ORCID: https://orcid.org/0000-0001-9861-6097, Kaltenpoth, Martin ORCID: https://orcid.org/0000-0001-9450-0345, Gershenzon, Jonathan ORCID: https://orcid.org/0000-0002-1812-1551 and Lehenberger, Maximilian
bioRxiv
: 2026.07.04.736475.
6 July 2026
Helicobacter pylori triggers gastric mucosal remodeling toward a fetal-like transcriptional program via stromal IL-1β signaling.
Beccaceci, Giulia ORCID: https://orcid.org/0000-0002-6453-3725, Müllerke, Stefanie, Berger, Hilmar ORCID: https://orcid.org/0000-0002-6304-4946, Täger, Christian, Möbius, Ronja ORCID: https://orcid.org/0009-0008-2988-8951, Fischer, Anne-Sophie ORCID: https://orcid.org/0000-0002-2176-1779, Hartl, Kimberly ORCID: https://orcid.org/0000-0002-2965-0512, Wizenty, Jonas ORCID: https://orcid.org/0000-0003-4261-0416, Mollenkopf, Hans-Joachim ORCID: https://orcid.org/0000-0003-1167-4783, Naumann, Michael ORCID: https://orcid.org/0000-0002-8060-2313, Lin, Manqiang ORCID: https://orcid.org/0000-0003-4093-9277 and Sigal, Michael ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 17
(1): 9510.
5 September 2026
Deep learning-based analysis of gene expression data and gene-related information in pediatric surgical oncology: a scoping review.
Berhe, Simon, Fuchs, Steffen E., Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117, van der Steeg, Alida F.W., Warmann, Steven W., Buser, Myrthe A.D. ORCID: https://orcid.org/0000-0003-0640-6434 and Markel, Moritz
Cancer Medicine 15
(5): e71976.
May 2026
Resource data for: Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome.
Boehm, Volker ORCID: https://orcid.org/0000-0001-7588-9842, Wallmeroth, Damaris ORCID: https://orcid.org/0000-0003-3437-4070, Wulf, Paul ORCID: https://orcid.org/0009-0002-6356-2361, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Teixeira Alves, Luiz Gustavo ORCID: https://orcid.org/0000-0002-5822-4168, Reinecke, Lucie ORCID: https://orcid.org/0009-0003-7083-0923, Riedel, Maximilian ORCID: https://orcid.org/0009-0002-9817-3083, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Franitza, Marek, Becker, Kerstin ORCID: https://orcid.org/0009-0009-7897-7181, Polkovnychenko, Karina, Del Giudice, Simone ORCID: https://orcid.org/0000-0003-0194-3767, Benlasfer, Nouhad, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734 and Gehring, Niels H. ORCID: https://orcid.org/0000-0001-7792-1164
[Dataset]
18 March 2026
Extrachromosomal DNA micronucleation constrains tumour fitness and improves patient survival.
Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Xu, R. ORCID: https://orcid.org/0000-0002-5618-246X, Tang, J., Gnanasekar, A., Herrmann, A., Wong, I.T.L., Zhang, S., Tu, F., Pilon, M., Kukalev, A. ORCID: https://orcid.org/0000-0001-5847-3773, Pardon, K., Sidorova, O. ORCID: https://orcid.org/0009-0004-1459-1662, Atta, J., Yu, Q. ORCID: https://orcid.org/0000-0002-2151-9624, Montouri, G., Pradella, D., Ilić, M., Suina, K., Novais-Cruz, M., Kaltenbach, S., Treue, D., Giurgiu-Kraljič, M. ORCID: https://orcid.org/0000-0001-5007-7442, Herzog, S., Hollinger, A.S., Wittstruck, N., Fernandez, M., Wolozyn, N., Becker, F., Louma, V.R., Yan, X., Schmargon, R. ORCID: https://orcid.org/0009-0009-3535-7185, Dörr, J. ORCID: https://orcid.org/0000-0002-4927-6548, Gamlin, D., Lehmann, A., Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Richter, M. ORCID: https://orcid.org/0000-0002-5339-0781, Dubois, F. ORCID: https://orcid.org/0000-0002-7654-6208, Simeoni, F., Pennycook, B.R., Hamilton, A., Lindemann, R.K., Dawes, C., Balmus, G., Hero, B., Fischer, M., Bafna, V., Verhaak, R., Wahl, G., Liu, Y., Koche, R.P., Papathanasiou, S., Medema, R., Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Ventura, A., Pombo, A. ORCID: https://orcid.org/0000-0002-7493-6288, Huang, W., Scheer, M., Werner, B., Chang, H.Y., Mischel, P.S. and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
bioRxiv
: 2025.04.15.648906.
19 February 2026
Coordinated interferon-γ/tumor necrosis factor axis drives selective loss of activated enteric glia in inflammatory bowel diseases.
Bubeck, Marvin, Penkert, Klara A. ORCID: https://orcid.org/0000-0002-9948-533X, Limberger, Heidi, González Acera, Miguel, Plattner, Christina, Ziegler, Svenja, Muppirala, Anoohya, Forster, Patrycja, Jakob, Manuel, Gamez-Belmonte, Reyes, Erkert, Lena, Kulkarni, Subhash, Günther, Claudia, Atreya, Raja, Kühl, Anja A., Hegazy, Ahmed N., Hildner, Kai, Trajanoski, Zlatko, Siegmund, Britta, Neurath, Markus F., Rao, Meenakshi, Progatzky, Fränze, Lie, Dieter Chichung, Becker, Christoph, Romagnani, Chiara, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Klose, Christoph S.N. and Patankar, Jay V.
Cellular and Molecular Gastroenterology and Hepatology 20
(10): 101827.
30 July 2026
(In Press)
Dynamics of a Hes1-Dll1 regulatory network in coupled muscle stem cells: stability, bifurcations, and coexistence of oscillatory states.
Bujtár, Zsófia ORCID: https://orcid.org/0000-0002-9988-4197, Goldenbogen, Björn ORCID: https://orcid.org/0000-0002-1456-5278 and Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868
bioRxiv
: 2026.07.29.741250.
30 July 2026
Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodeling.
Bulankina, Anna V. ORCID: https://orcid.org/0009-0003-0992-7320, Richter, Rebecca M. ORCID: https://orcid.org/0000-0002-3831-7666, Nettles, James H. ORCID: https://orcid.org/0000-0002-5683-8481, Yamane, Daisuke ORCID: https://orcid.org/0000-0003-1592-9368, Grimm, Christian, Karami, Yasaman ORCID: https://orcid.org/0000-0001-8413-2665, Stanton, Richard A. ORCID: https://orcid.org/0000-0003-4810-7002, Introini, Bianca, Hermann, Jonas, Charif, Hanaa, König, Mia S. ORCID: https://orcid.org/0009-0009-5173-1798, Stroß, Claudia, Ortiz, Cristina, Kraus, Nico ORCID: https://orcid.org/0000-0002-5162-1048, Wood, Daniel, Galceran, Facundo ORCID: https://orcid.org/0000-0001-5023-0582, Abele, Rupert ORCID: https://orcid.org/0000-0001-6899-293X, Maigret, Bernard ORCID: https://orcid.org/0000-0002-1983-1950, Schinazi, Raymond F. ORCID: https://orcid.org/0000-0002-6688-3614, Zeuzem, Stefan, Biondi, Ricardo M. ORCID: https://orcid.org/0000-0002-8873-7167, Yi, MinKyung, Tampé, Robert ORCID: https://orcid.org/0000-0002-0403-2160, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Welsch, Christoph ORCID: https://orcid.org/0000-0002-1823-4863
Science Advances 12
(14): eaeb8863.
3 April 2026
Integrated left ventricular multi-omics landscape of human cardiometabolic HFpEF.
Capone, Federico ORCID: https://orcid.org/0000-0001-8127-5564, Rommel, Karl-Philipp, Forbes, Martin ORCID: https://orcid.org/0000-0001-7775-8352, Fahjen, Pauline ORCID: https://orcid.org/0000-0002-5015-0643, Strocchi, Stefano ORCID: https://orcid.org/0009-0002-8879-6156, Rosch, Sebastian, Wang, Rongling ORCID: https://orcid.org/0000-0001-8719-938X, Bode, David, Nambiar, Natasha ORCID: https://orcid.org/0009-0004-3538-8081, Eroglu, Tolga ORCID: https://orcid.org/0000-0003-3404-2754, Santiago-Padilla, Leandro ORCID: https://orcid.org/0000-0002-0873-7205, Morieri, Mario Luca, Liu, Luo, Farrelly, Catherine, Vacca, Antonio ORCID: https://orcid.org/0000-0003-0051-7723, Mastrobuoni, Guido ORCID: https://orcid.org/0000-0003-4509-1295, Jung, Simone, Diezel, Saskia A., Liévano Contreras, Sarah V., Hübner, Norbert ORCID: https://orcid.org/0000-0002-1218-6223, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299, Lurz, Philipp and Schiattarella, Gabriele G. ORCID: https://orcid.org/0000-0002-7582-7171
Cardiovascular Research 122
(8): 984-1000.
May 2026
Current treatment strategies for first relapse of high-risk neuroblastoma.
Castelli, Sveva, Schulze, Franziska ORCID: https://orcid.org/0009-0008-6237-5111, Thole-Kliesch, Theresa M., Astrahantseff, Kathy ORCID: https://orcid.org/0000-0002-7872-1997, Barone, Giuseppe ORCID: https://orcid.org/0000-0003-3264-1913, Beck-Popovic, Maja ORCID: https://orcid.org/0000-0001-9502-5697, Berlanga, Pablo ORCID: https://orcid.org/0000-0003-1110-7789, Corbacioglu, Selim ORCID: https://orcid.org/0000-0003-1070-8486, Fischer, Matthias ORCID: https://orcid.org/0000-0003-1363-1242, Gambart, Marion, George, Sally L., Chesler, Louis ORCID: https://orcid.org/0000-0001-7842-2068, Gray, Juliet C., Hero, Barbara, Künkele, Annette ORCID: https://orcid.org/0000-0002-8406-5412, Flaadt, Tim ORCID: https://orcid.org/0000-0002-2729-9941, Lang, Peter, Lode, Holger N. ORCID: https://orcid.org/0000-0002-1201-208X, Molenaar, Jan J. ORCID: https://orcid.org/0000-0002-2007-0431, Schleiermacher, Gudrun ORCID: https://orcid.org/0000-0002-0133-5879, Rosswog, Carolina ORCID: https://orcid.org/0000-0002-8855-6198, Moreno, Lucas, Owens, Cormac, Rubio-San-Simón, Alba ORCID: https://orcid.org/0000-0001-6426-7423, Schulte, Johannes H., Simon, Thorsten ORCID: https://orcid.org/0000-0002-3425-8451, Tweddle, Deborah A. ORCID: https://orcid.org/0000-0003-2208-3970, Deubzer, Hedwig E. ORCID: https://orcid.org/0000-0002-6115-4893 and Eggert, Angelika
European Journal of Cancer 236
: 116254.
11 March 2026
Deep visual proteomics uncovers nociceptor diversity and pain targets.
Chakrabarti, Sampurna ORCID: https://orcid.org/0000-0002-2750-3877, Makhmut, Anuar ORCID: https://orcid.org/0009-0009-6913-4289, Mohammadi, Atena, Luo, Wenhan ORCID: https://orcid.org/0000-0001-5202-8855, Wang, Lin ORCID: https://orcid.org/0000-0002-8395-6184, Lewin, Gary R. ORCID: https://orcid.org/0000-0002-2890-6352 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
Nature Communications 17
(1): 3437.
13 April 2026
Extrachromosomal DNA associates with poor survival across a broad spectrum of childhood solid tumors.
Chapman, Owen S. ORCID: https://orcid.org/0000-0001-7923-9273, Sridhar, Sunita, Chow, Eugene Yui-Ching, Kenkre, Rishaan, Kirkland, Jonathan, Dutta, Aditi, Wang, Shanqing, Goto, Riki, Zhang, Wenshu, Brown, Miguel, Luebeck, Jens S. ORCID: https://orcid.org/0000-0003-4391-979X, Hui, Hui, Wang, Jessica, Lo, Yan Yuen, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Wang, Shanzheng, Okonechnikov, Konstantin ORCID: https://orcid.org/0000-0002-3409-2340, Ghasemi, David R., Pajtler, Kristian W., Gojo, Johannes, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Kool, Marcel, Bafna, Vineet ORCID: https://orcid.org/0000-0002-5810-6241, Kawauchi, Daisuke, Paul, Megan, Yip, Kevin, Mesirov, Jill P. and Chavez, Lukas
medRxiv
: 2025.07.22.24308163v3.
9 April 2026
Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D.
Chowdhury, Biswanath, Zhu, Kaiyuan, Li, Chaohui, Alsing, Jessica, Luebeck, Jens ORCID: https://orcid.org/0000-0003-4391-979X, Stefanova, Maria E., Chapman, Owen S., Kraft, Katerina, Zhang, Shu, Lim, Jun Yi Stanley, Xie, Yipeng, Kim, Yoon Jung, Wu, Sihan, Chavez, Lukas, Nir, Guy, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Mischel, Paul S., Chang, Howard Y. and Bafna, Vineet
[Dataset]
24 January 2026
Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D.
Chowdhury, Biswanath ORCID: https://orcid.org/0000-0003-3465-7505, Zhu, Kaiyuan ORCID: https://orcid.org/0000-0001-9976-6505, Li, Chaohui ORCID: https://orcid.org/0009-0009-6196-1191, Alsing, Jessica ORCID: https://orcid.org/0000-0002-8558-6471, Luebeck, Jens ORCID: https://orcid.org/0000-0003-4391-979X, Stefanova, Maria E., Chapman, Owen S., Kraft, Katerina, Zhang, Shu, Lim, Jun Yi Stanley, Xie, Yipeng, Kim, Yoon Jung, Wu, Sihan ORCID: https://orcid.org/0000-0001-8329-7492, Chavez, Lukas, Nir, Guy ORCID: https://orcid.org/0000-0001-9268-6596, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Mischel, Paul S. ORCID: https://orcid.org/0000-0002-4560-2211, Chang, Howard Y. ORCID: https://orcid.org/0000-0002-9459-4393 and Bafna, Vineet ORCID: https://orcid.org/0000-0002-5810-6241
Nature Communications 17
(1): 894.
23 January 2026
Deep visual proteomics uncovers nociceptor diversity and pain targets.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
10 April 2026
Non-viral in situ gene editing effectively and safely rescues congenital ichthyosis-causing mutations in human skin.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
23 January 2026
An ultrasensitive spatial tissue proteomics workflow exceeding 100 proteomes per day.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
5 January 2026
OpenDVP: an experimental and computational framework for community-empowered deep visual proteomics.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081 and Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799
[Dataset]
31 May 2026
Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma.
Czernilofsky, Felix, Mathioudaki, Anna ORCID: https://orcid.org/0000-0003-4617-7015, Jopp-Saile, Lea ORCID: https://orcid.org/0000-0002-7032-3003, Lutz, Raphael, Vonficht, Dominik ORCID: https://orcid.org/0000-0002-5579-7083, Wang, Xi ORCID: https://orcid.org/0000-0002-7572-6354, Schniederjohann, Christina, Voehringer, Harald, Roider, Tobias, Baertsch, Marc-Andrea ORCID: https://orcid.org/0000-0002-4000-6904, Rodemer, Claus, Löffler-Wirth, Henry, Grau, Michael, Fitzgerald, Donnacha ORCID: https://orcid.org/0000-0003-4927-7484, Mammen, Johannes, Kosla, Jan, Liebers, Nora ORCID: https://orcid.org/0009-0008-3887-9416, Bruch, Peter-Martin ORCID: https://orcid.org/0000-0002-9992-3109, Ordoñez-Rueda, Diana, Brobeil, Alexander, Mechtersheimer, Gunhild, Pabst, Caroline ORCID: https://orcid.org/0000-0001-9716-5909, Müller-Tidow, Carsten ORCID: https://orcid.org/0000-0002-7166-5232, Trumpp, Andreas ORCID: https://orcid.org/0000-0002-6212-3466, Seifert, Marc ORCID: https://orcid.org/0000-0001-9453-369X, Neumann, Frank, Heikenwälder, Mathias ORCID: https://orcid.org/0000-0002-3135-2274, Benes, Vladimir ORCID: https://orcid.org/0000-0002-0352-2547, Huber, Wolfgang, Distler, Jörg ORCID: https://orcid.org/0000-0001-7408-9333, Lenz, Georg ORCID: https://orcid.org/0000-0002-4728-1693, Binder, Hans ORCID: https://orcid.org/0000-0002-2242-4678, Siebert, Reiner, Nolan, Garry P. ORCID: https://orcid.org/0000-0002-8862-9043, Gerstung, Moritz ORCID: https://orcid.org/0000-0001-6709-963X, Zaugg, Judith B. ORCID: https://orcid.org/0000-0001-8324-4040, Hübschmann, Daniel ORCID: https://orcid.org/0000-0002-6041-7049, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051 and Dietrich, Sascha ORCID: https://orcid.org/0000-0002-0648-1832
Nature Cancer 7
(3): 538-552.
March 2026
Efficient CRISPR/Cas9-mediated homology independent sequence replacement in vivo and non-dividing primary cells.
Dang, Tu Ngoc ORCID: https://orcid.org/0009-0001-0138-7599, Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752, Zimmer, Anja, Lebedin, Mikhail ORCID: https://orcid.org/0000-0002-3877-7195, Bahry, Ella ORCID: https://orcid.org/0000-0002-6358-2576, Marti Grifol, Claudia ORCID: https://orcid.org/0009-0004-9929-0585, Esser, Markus, Sevim Wunderlich, Seren ORCID: https://orcid.org/0009-0008-2771-4149, Miller, Duncan C. ORCID: https://orcid.org/0000-0001-9852-677X, Diecke, Sebastian ORCID: https://orcid.org/0000-0002-5219-5992 and Kuehn, Ralf ORCID: https://orcid.org/0000-0003-1694-9803
bioRxiv
: 2026.07.24.740048.
24 July 2026
Single-cell template strand sequencing reveals culture-induced chromosomal instability in a gibbon cell line.
Daponte, Alessia, Chirico, Gerardina, Paparella, Annalisa, Montanari, Annalaura, Manzari, Caterina, Macino, Martina ORCID: https://orcid.org/0000-0002-8730-9005, Dionisi Dyck, Oliver ORCID: https://orcid.org/0000-0002-0410-1736, De Leonardis, Francesco, Maggiolini, Flavia Angela Maria, L'Abbate, Alberto, Montinaro, Francesco, Louzada, Sandra, Ventura, Mario, Sanders, Ashley D. ORCID: https://orcid.org/0000-0003-3945-0677, Antonacci, Francesca and Catacchio, Claudia Rita
Genome Research 36
(5): 938-948.
May 2026
In remembrance of Professor Zelig Eshhar: a life committed to CAR-T.
Debets, Reno, Hawkins, Robert, Gilham, David, Gorochov, Guy, Schumacher, Ton, Uckert, Wolfgang, Blankenstein, Thomas ORCID: https://orcid.org/0000-0002-3357-4321, Crawford, Dorothy, Taylor, Naomi, Szöllösi, János, Stauss, Hans, Mondino, Anna, Allavena, Paola, Alarcón, Balbino, Büning, Hildegard and Abken, Hinrich
Human Gene Therapy 37
(1-2): 65-67.
1 January 2026
Aberrant SUMOylation restricts the targetable cancer immunopeptidome.
Demel, Uta M. ORCID: https://orcid.org/0000-0002-6480-4185, Meurer, Anna, Zaghla, Badeel Kh Q., Atay, Bilge, Steiert, Daniel, Hummel, Luca V., Isaakidis, Konstandina, Zang, Chuanbing, Korenkov, Michael ORCID: https://orcid.org/0000-0002-2988-8483, Schielin, Marlon, Yousefian, Schayan ORCID: https://orcid.org/0000-0003-0902-0369, Mecklenbräuker, Shima, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Müller, Stefan, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Klatt, Martin G. and Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958
Advanced Science 13
(17): e11449.
23 March 2026
Expanding the human proteome with microproteins and peptideins.
Deutsch, Eric W., Kok, Leron W., Mudge, Jonathan M., Valls, Cristian F., Jungreis, Irwin, Ruiz-Orera, Jorge ORCID: https://orcid.org/0000-0002-8317-0034, Sun, Zhi, Kusebauch, Ulrike, Fierro-Monti, Ivo, Abelin, Jennifer G., Alba, M. Mar, Aspden, Julie L., Bandyopadhyay, Sreejan, Banerjee, Kaushik, Baranov, Pavel V., Bazzini, Ariel A., Bourassa, Francis, Bruford, Elspeth A., Calviello, Lorenzo, Carr, Steven A., Carvunis, Anne-Ruxandra, Chothani, Sonia, Clauwaert, Jim, Dean, Kellie, Faridi, Pouya, Frankish, Adam, Goodale, Amy, Green, Thomas, Hubner, Norbert ORCID: https://orcid.org/0000-0002-1218-6223, Ingolia, Nicholas T., Kellis, Manolis, Magrane, Michele, Martin, Maria Jesus, Martinez, Thomas F., Menschaert, Gerben, Ohler, Uwe ORCID: https://orcid.org/0000-0002-0881-3116, Orchard, Sandra, Potter, Alisa, Rackham, Owen J.L., Rees, Matthew G., Root, David E., Roth, Jennifer A., Roucou, Xavier, Sialana, Fernando J., Slavoff, Sarah A., Świrski, Michał I., Tierney, Jack A.S., Trifiro, Félix-Antoine, Valen, Eivind, Vasylieva, Valeriia, Wacholder, Aaron, Wang, Shengbo, Wang, Li, Weissman, Jonathan S., Wu, Wei, Xie, Zhi, Choudhary, Jyoti S., Bassani-Sternberg, Michal, Vizcaíno, Juan Antonio, Ternette, Nicola, Brunet, Marie A., Moritz, Robert L., Prensner, John R. and van Heesch, Sebastiaan
Nature 654
(8119): 813-825.
18 June 2026
Effect of temperature ramp in rapid folding of 3D DNA origami structures.
Dey, Anurit ORCID: https://orcid.org/0009-0004-2272-5544, Al Hussain, Mohammed Mustafa A. ORCID: https://orcid.org/0000-0001-7132-8482, Pham, Xuan‐Hung ORCID: https://orcid.org/0000-0002-4927-7102, Loo, Jacky ORCID: https://orcid.org/0000-0002-0355-8865, Natarajan, Ashwin Karthick ORCID: https://orcid.org/0000-0001-7897-708X and Kuzyk, Anton ORCID: https://orcid.org/0000-0001-8060-6122
Small Structures 7
(2): e202500682.
February 2026
Conservation and specificity in Bacillus biofilm dynamics: on structure and function of B. cereus Camelysins.
Diehl, Anne, Lindemann, Florian, Cremer, Nils, Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Hiller, Matthias, van Rossum, Barth, Leidert, Martina, Turgay, Kürşad and Oschkinat, Hartmut
Journal of Molecular Biology 438
(6): 169661.
15 March 2026
Chronic infection perturbs the affinity hierarchy of antiviral B cells.
Dimitrova, Mirela, Abreu-Mota, Tiago, Fixemer, Jonas, Bonilla, Weldy V., Marx, Anna-Friederike, Lu, Min, Tintignac, Karen, Kastner, Anna Lena, Ertuna, Yusuf I., Florova, Marianna ORCID: https://orcid.org/0009-0008-9529-7041, Ciancaglini, Matias ORCID: https://orcid.org/0000-0002-1296-5606, Narr, Kerstin, Stauffer, Karsten, Roux, Julien, Demougin, Philippe ORCID: https://orcid.org/0009-0002-2820-9909, Wagner, Ingrid, Merkler, Doron ORCID: https://orcid.org/0000-0002-0247-2007 and Pinschewer, Daniel D. ORCID: https://orcid.org/0000-0002-1594-3189
Proceedings of the National Academy of Sciences of the United States of America 123
(14): e2532422123.
7 April 2026
Autophagy selectively clears ER in TNF-α-induced muscle atrophy.
Dueren, Ursula K. ORCID: https://orcid.org/0009-0006-4407-9031, Wei, Alan An Jung ORCID: https://orcid.org/0000-0003-4255-9470, Gressler, A. Elisabeth ORCID: https://orcid.org/0000-0003-3229-1554, Rapp, Simon ORCID: https://orcid.org/0000-0002-5141-0611, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Kerridge, Robert, Buonomo, Viviana, Viviana, Paolo ORCID: https://orcid.org/0000-0002-9942-9389, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Simon, Anna Katharina ORCID: https://orcid.org/0000-0002-4077-7995 and Sommer, Thomas ORCID: https://orcid.org/0000-0001-9990-5202
Autophagy Reports 5
(1): 2649064.
14 April 2026
Bruton tyrosine kinase inhibition limits multiple sclerosis disease-driving inflammation while promoting regulatory B cells.
Dybowski, Sarah, Thode, Jacqueline, Freier, Marie, Saberi, Darius, Nessler, Stefan, Geladaris, Anastasia, Häusser-Kinzel, Silke, Ringelstein, Marius, Torke, Sebastian ORCID: https://orcid.org/0000-0002-1029-3623 and Weber, Martin S.
Neurology Neuroimmunology & Neuroinflammation 13
(1): e200510.
January 2026
Mapping the SHP2 allosteric pocket with target-biased covalent fragments.
Efrém, Nina-Louisa, Csorba, Noémi, Amoussa, Machoud, Ábrányi-Balogh, Péter, Guo, Ziqiong, Petri, László, Bo, Feng, Di Lorenzo, Vincenzo, Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Szalai, Tibor Viktor ORCID: https://orcid.org/0009-0000-4088-3117, Mihalovits, Levente, Simon, József, Li, Jia, Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, Keserű, György M. and Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330
ChemBioChem 27
(8): e70310.
April 2026
Perturb-seq reveals TCF7 as a transcriptional link between MAPK- and Wnt-driven gene expression.
El Kassem, Ghanem ORCID: https://orcid.org/0009-0009-2623-0684, Sieber, Anja ORCID: https://orcid.org/0000-0001-6588-8547, Klinger, Bertram, Uhlitz, Florian, Steinbrecht, David, van Bentum, Mirjam, Khan, Shawez, Hillmer, Jasmine, von Schlichting, Jennifer, Schäfer, Reinhold, Blüthgen, Nils ORCID: https://orcid.org/0000-0002-0171-7447 and Boettcher, Michael ORCID: https://orcid.org/0000-0003-0986-4465
Nucleic Acids Research 54
(14): gkag718.
12 August 2026
FOXO1 re-expression with a dual-recombinase allele rescues class switching in germinal center B cells.
Farré Díaz, Carlota ORCID: https://orcid.org/0000-0003-4306-2108, Kabrani, Eleni ORCID: https://orcid.org/0000-0003-0834-9912, Winkler, Wiebke ORCID: https://orcid.org/0000-0001-8807-9259, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Wollert-Wulf, Brigitte ORCID: https://orcid.org/0009-0000-0257-4049, Salomon, Claudia ORCID: https://orcid.org/0009-0000-6723-6497, Wunderlich, F. Thomas ORCID: https://orcid.org/0000-0002-9209-3501, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Janz, Martin ORCID: https://orcid.org/0000-0002-1127-0044 and Rajewsky, Klaus ORCID: https://orcid.org/0000-0002-6633-6370
Journal of Experimental Medicine 223
(3): e20241136.
2 March 2026
Combinatorial tumor suppressor gene targeting immortalizes primary pancreatic ductal cells, resulting in temporal, deterministic structural patterns across the genome.
Felsenstein, Matthäus, Hu, Mengwen, Ma, Dou, Tamboli, Jenny, Jin, Cao Zhong Jing, Wang, Ruonan, Hui, Luan Xiao, Dubois, Frank ORCID: https://orcid.org/0000-0002-7654-6208, Neumann, Christopher, Dolnik, Anna, Hillebrandt, Karl Herbert, Haderer, Luna, Giurgiu, Madalina ORCID: https://orcid.org/0000-0001-5007-7442, Henssen, Anton ORCID: https://orcid.org/0000-0003-1534-778X, Kübler, Kirsten, Pratschke, Johann, Malinka, Thomas, Sauer, Igor, Wood, Laura ORCID: https://orcid.org/0000-0003-3096-652X and Roberts, Nicholas ORCID: https://orcid.org/0000-0002-8709-0664
Research Square
: rs-9124723/v1.
27 March 2026
Bispecific BAFF-R/BCMA CAR T cells control growth of heterogeneous plasma cells in multiple myeloma.
Fiori, Agnese ORCID: https://orcid.org/0000-0003-0440-4857, Zimmermann, Karin, Li, Anna ORCID: https://orcid.org/0000-0002-4702-7783, Westermann, Jörg, Anagnostopoulos, Ioannis, Menzel, Lutz ORCID: https://orcid.org/0000-0002-3816-6255, Bunse, Mario ORCID: https://orcid.org/0000-0002-7554-2520, Erdlei, Henry, Jayarajan, Jeyan ORCID: https://orcid.org/0009-0009-6205-143X, Grünschläger, Florian ORCID: https://orcid.org/0000-0003-0021-6912, Ortiz-Aguirre, Juan Pablo ORCID: https://orcid.org/0000-0002-6557-0069, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Teßmann, Uwe-Jens, Freitag, Jens, Rosenwald, Andreas, Kwak, Larry, Wang, Xiuli, Dong, Zhenyuan, Cha, Soungchul, Reiser, John, Peralta, Eigen, Valamehr, Bahram, Krönke, Jan, Höpken, Uta E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, Armin ORCID: https://orcid.org/0000-0001-7490-1950
Molecular Therapy 34
(3): 1399-1420.
4 March 2026
Mesenchymal R-spondin 3 promotes an immunogenic tumor microenvironment with adaptive immune resistance in human gastric adenocarcinoma.
Fischer, Anne-Sophie ORCID: https://orcid.org/0000-0002-2176-1779, Arnold, Alexander, Berger, Hilmar, Müllerke, Stefanie, Wizenty, Jonas, Mollenkopf, Hans-Joachim, Horst, David, Tacke, Frank, Treese, Christoph ORCID: https://orcid.org/0000-0001-9120-6773 and Sigal, Michael ORCID: https://orcid.org/0000-0003-4772-0761
Gastric Cancer
24 August 2026
(In Press)
Spatial single-cell proteomics reveals molecular trajectories of tangle-bearing neurons in Alzheimer’s disease.
Foiani, M.S. ORCID: https://orcid.org/0000-0003-4157-2606, Bourdenx, M. ORCID: https://orcid.org/0000-0002-9799-9222, Kraller, L. ORCID: https://orcid.org/0009-0006-9785-3596, Nirujogi, R.S. ORCID: https://orcid.org/0000-0002-3177-8566, Yiu, A., Davies, H., Patel, S., Damoc, L.S., Mitchener, L., Jaunmuktane, Z. ORCID: https://orcid.org/0000-0001-7738-8881, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081 and Duff, K.E. ORCID: https://orcid.org/0000-0002-6177-868X
bioRxiv
: 2026.04.26.720932.
29 April 2026
Design of combination therapeutics from protein response to drugs in ovarian cancer cells.
Franz, A., Shen, C., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Munroe, K., Charaoui, L., Korkut, A. ORCID: https://orcid.org/0000-0001-8072-9026, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799, Luna, A. ORCID: https://orcid.org/0000-0001-5709-371X and Sander, C. ORCID: https://orcid.org/0000-0001-6059-6270
bioRxiv
: 2025.04.28.651139.
8 January 2026
Lineage origin and developmental context shape tumor states in MYCN-dependent zebrafish neuroblastoma.
Fresmann, Nora ORCID: https://orcid.org/0000-0002-9233-5101, Köppke, Julia, Gauert, Anton ORCID: https://orcid.org/0000-0002-3013-5374, Senoussi, Anis ORCID: https://orcid.org/0000-0002-7066-8917, Olivares-Chauvet, Pedro ORCID: https://orcid.org/0009-0008-4684-255X, Grammatikaki, Aliki ORCID: https://orcid.org/0009-0000-8469-4254, Schott, Marie ORCID: https://orcid.org/0009-0000-7393-2421, Höfer, Lennart, Jens, Marvin ORCID: https://orcid.org/0000-0002-6660-8743, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Spanjaard, Bastiaan ORCID: https://orcid.org/0000-0003-1309-8839, Hagemann, Anja I.H. ORCID: https://orcid.org/0000-0001-5491-4607 and Junker, Jan Philipp ORCID: https://orcid.org/0000-0002-2826-8290
bioRxiv
: 2025.10.13.682025v2.
3 August 2026
Immunofluorescence imaging-guided laser microdissection for ultralow input spatial tissue proteomics.
Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
Methods in Molecular Biology 3015
: 83-94.
2026
Pathway for the development of ATR inhibitors in pediatric malignancies: an ACCELERATE multistakeholder analysis.
Gatz, Susanne A. ORCID: https://orcid.org/0000-0002-6438-9778, Glade-Bender, Julia ORCID: https://orcid.org/0000-0001-5316-6440, Pearson, Andrew D.J. ORCID: https://orcid.org/0000-0002-8738-5913, Ortiz, Michael V. ORCID: https://orcid.org/0000-0001-9379-314X, Bernardi, Ronald, Chesler, Lou ORCID: https://orcid.org/0000-0001-7842-2068, Clifford, Steve ORCID: https://orcid.org/0000-0002-8573-8009, Cohen-Gogo, Sarah ORCID: https://orcid.org/0000-0002-8852-1104, De La Cuesta, Esther ORCID: https://orcid.org/0000-0001-7072-1493, de Rojas, Teresa ORCID: https://orcid.org/0000-0001-7749-8423, Durinck, Kaat ORCID: https://orcid.org/0000-0003-1762-5739, Federico, Sara ORCID: https://orcid.org/0000-0002-5807-4876, Fox, Elizabeth ORCID: https://orcid.org/0000-0002-9998-5326, George, Sally ORCID: https://orcid.org/0000-0003-2777-4922, Gounaris, Ioannis ORCID: https://orcid.org/0000-0003-2755-6597, Henssen, Anton George ORCID: https://orcid.org/0000-0003-1534-778X, Irwin, Meredith ORCID: https://orcid.org/0000-0002-2452-5181, Kool, Marcel, Lau, Alan ORCID: https://orcid.org/0000-0003-1055-9812, Nysom, Karsten ORCID: https://orcid.org/0000-0003-2935-0058, Pappo, Alberto ORCID: https://orcid.org/0000-0002-5338-3979, Pennock, Gregory K., Pfister, Stefan M., Scobie, Nicole ORCID: https://orcid.org/0000-0002-6539-2741, Slotkin, Emily K. ORCID: https://orcid.org/0000-0002-4463-5759, Smith, Malcolm ORCID: https://orcid.org/0000-0001-9880-9876, Speleman, Frank, Stewart, Elizabeth A., Weigel, Brenda J. ORCID: https://orcid.org/0000-0003-1080-1402 and Vassal, Gilles ORCID: https://orcid.org/0000-0003-1780-8869
JCO Precision Oncology 10
: e2500642.
January 2026
Therapy induced senescence promotes immunogenicity in acute myeloid Leukemia through reduced EZH2 activity.
Gilioli, Diego, Fusco, Simona, Tavella, Teresa, Volpari, Tatiana, Santoro, Antonella, Schönlein, Martin, Giannetti, Kety, Carsana, Edoardo, Gualandi, Nicolò, Noberini, Roberta, Brombin, Chiara, Russo, Salvatore, Feola, Sara, Giannoula, Yvonne, Branca, Rui M M, Lehtiö, Janne, Sikanen, Tiina M, Haapala, Markus, Passerini, Laura, Andrisani, Angela, Farina, Giacomo, Zangari, Alessia, Conti, Anastasia, Della Volpe, Lucrezia, Barcella, Matteo, Beretta, Stefano, Aletti, Federico Mario, Carrabba, Matteo Giovanni, Gregori, Silvia, Bonini, Chiara, Merelli, Ivan, Ciceri, Fabio, Cerullo, Vincenzo, Bonaldi, Tiziana, Vago, Luca, Schmitt, Clemens A. ORCID: https://orcid.org/0000-0002-4731-2226 and Di Micco, Raffaella
Nature Communications 17
(1): 9151.
4 September 2026
Integrative genomics of the siphonophore Physalia utriculus reveals the regulatory logic of colonial division of labour and the molecular basis of venom activity.
González-Rajal, Álvaro ORCID: https://orcid.org/0000-0002-9230-0339, D’Araujo, Tian Y. ORCID: https://orcid.org/0000-0002-0674-361X, Ovchinnikov, Vladimir ORCID: https://orcid.org/0000-0003-0350-8478, García-Junco Alcalá, Jesús L. ORCID: https://orcid.org/0009-0003-0581-7714, Wang, Tianfang ORCID: https://orcid.org/0000-0002-4876-7767, Lausen, Blake ORCID: https://orcid.org/0009-0007-2292-6452, Brethouwer, Thirsa ORCID: https://orcid.org/0009-0009-0522-9799, Angeloni, Allegra ORCID: https://orcid.org/0000-0002-8104-718X, Ross, Samuel E. ORCID: https://orcid.org/0000-0002-0588-1703, Burgos-Ruiz, Ana María ORCID: https://orcid.org/0009-0006-3095-8668, Álvarez-Presas, Marta ORCID: https://orcid.org/0000-0002-4825-9965, Mota-Gómez, Irene ORCID: https://orcid.org/0000-0001-8308-8017, Acemel, Rafael D. ORCID: https://orcid.org/0000-0003-4120-0140, Harris, Richard J. ORCID: https://orcid.org/0000-0002-4412-2275, Loi-Luu, Phuc ORCID: https://orcid.org/0000-0001-8045-718X, Jimenez, Georgia E. ORCID: https://orcid.org/0009-0003-1978-735X, Daners, Andrea ORCID: https://orcid.org/0009-0004-4782-539X, Ferguson, James M. ORCID: https://orcid.org/0000-0002-6192-6937, Hammond, Jillian M. ORCID: https://orcid.org/0000-0002-4045-4571, Gamaarachchi, Hasindu ORCID: https://orcid.org/0000-0002-9034-9905, Degnan, Bernard M. ORCID: https://orcid.org/0000-0001-7573-8518, Degnan, Sandie M. ORCID: https://orcid.org/0000-0001-8003-0426, Mackay, Joel P. ORCID: https://orcid.org/0000-0001-7508-8033, Undheim, Eivind A. B. ORCID: https://orcid.org/0000-0002-8667-3999, Ruiz-Trillo, Iñaki ORCID: https://orcid.org/0000-0001-6547-5304, Clark, Susan J. ORCID: https://orcid.org/0000-0001-5925-5030, Tena, Juan J. ORCID: https://orcid.org/0000-0001-8165-7984, Lupiáñez, Darío G. ORCID: https://orcid.org/0000-0002-3165-036X, Church, Samuel H. ORCID: https://orcid.org/0000-0002-8451-103X, Dunn, Casey W. ORCID: https://orcid.org/0000-0003-0628-5150, Marletaz, Ferdinand ORCID: https://orcid.org/0000-0001-8124-4266, Deveson, Ira W. ORCID: https://orcid.org/0000-0003-3861-0472, Cummins, Scott F. ORCID: https://orcid.org/0000-0002-1454-2076, Neely, G. Gregory ORCID: https://orcid.org/0000-0002-1957-9732, de Mendoza, Alex ORCID: https://orcid.org/0000-0002-6441-6529 and Bogdanovic, Ozren ORCID: https://orcid.org/0000-0001-5680-0056
bioRxiv
: 2026.08.01.742136.
1 August 2026
Pre-existing chromatin accessibility primes δ-cells for injury-induced endocrine plasticity.
Gräßlin, Jo ORCID: https://orcid.org/0000-0003-0641-9913, Chawla, Prateek, Subramanian, Padmapriya, Rajendran, Anuradha, Walda, Emilie Ida Christine, Froschauer, Alexander, Ninov, Nikolay and Junker, Jan Philipp ORCID: https://orcid.org/0000-0002-2826-8290
bioRxiv
: 2026.05.24.727280v2.
10 July 2026
A kinetics-based model of hematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells - code & data repository.
Grünschläger, Florian ORCID: https://orcid.org/0000-0003-0021-6912, Rodriguez-Correa, Esther, Nizharadze, Tamar, Sedlmeier, Anastasia, Höfer, Thomas, Hübschmann, Daniel, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051 and Milsom, Mick
[Dataset]
April 2026
EMD-56110: Flat clathrin lattice on endosomes.
Gul, M. ORCID: https://orcid.org/0000-0001-5513-1866, Hakala, M., Moparthi, S.B., Ganeva, I., Bernat-Silvestre, C., Marcuello, C., Espadas, J., Colom, A., Kukulski, W., Vassilopoulos, S., Kaksonen, M., Roux, A. and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
[Dataset]
20 May 2026
Naked mole-rat 80S ribosome in post-translocation non-rotated state.
Gul, M. ORCID: https://orcid.org/0000-0001-5513-1866 and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
[Dataset]
17 June 2026
Naked mole-rat 80S ribosome in pre-translocation rotated hybrid state.
Gul, M. ORCID: https://orcid.org/0000-0001-5513-1866 and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
[Dataset]
17 June 2026
C-COMPASS: a user-friendly neural network tool profiles cell compartments at protein and lipid levels.
Haas, Daniel T., Weindl, Daniel ORCID: https://orcid.org/0000-0001-9963-6057, Kakimoto, Pamela, Trautmann, Eva-Maria ORCID: https://orcid.org/0009-0002-0691-0489, Schessner, Julia P., Mao, Xia, Gerl, Mathias J. ORCID: https://orcid.org/0000-0002-8074-7221, Gerwien, Maximilian ORCID: https://orcid.org/0000-0002-2884-4155, Müller, Timo D., Klose, Christian, Cheng, Xiping, Hasenauer, Jan ORCID: https://orcid.org/0000-0002-4935-3312 and Krahmer, Natalie ORCID: https://orcid.org/0000-0003-4063-7367
Nature Methods 23
(1): 118-130.
January 2026
EMD-56112: Cryo-electron tomogram of endosomes in HeLa cells.
Hakala, M., Moparthi, S.B., Ganeva, I., Gul, M. ORCID: https://orcid.org/0000-0001-5513-1866, Bernat-Silvestre, C., Marcuello, C., Espadas, J., Colom, A., Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274, Kukulski, W., Vassilopoulos, S., Kaksonen, M. and Roux, A.
[Dataset]
20 May 2026
Two-dimensional HRS condensates drive the assembly of flat clathrin lattices on endosomes.
Hakala, Markku ORCID: https://orcid.org/0000-0002-3485-6080, Moparthi, Satish Babu ORCID: https://orcid.org/0000-0001-7493-3848, Ganeva, Iva, Gül, Mehmet ORCID: https://orcid.org/0000-0001-5513-1866, Bernat-Silvestre, César, Marcuello, Carlos ORCID: https://orcid.org/0000-0003-3459-8605, Espadas, Javier ORCID: https://orcid.org/0000-0002-4559-5410, Colom, Adai ORCID: https://orcid.org/0000-0003-4869-8981, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274, Kukulski, Wanda ORCID: https://orcid.org/0000-0002-2778-3936, Vassilopoulos, Stéphane ORCID: https://orcid.org/0000-0003-0172-330X, Kaksonen, Marko ORCID: https://orcid.org/0000-0003-3645-7689 and Roux, Aurélien ORCID: https://orcid.org/0000-0002-6088-0711
Nature Communications 17
(1): 6336.
16 July 2026
Mutant IDH1 blocks neutropoiesis by repressing myeloid progenitor programs.
Hakobyan, Mariam, Langstein, Jens, Ramos Medina, María José, Kleinert, Emely, Schönung, Maximilian ORCID: https://orcid.org/0000-0002-9778-9698, Hartmann, Mark ORCID: https://orcid.org/0000-0002-4072-4658, Rohdjess, Hannah ORCID: https://orcid.org/0009-0001-4985-1231, Wojtarowicz, Jessica, Staeble, Sina ORCID: https://orcid.org/0000-0002-5962-2440, Türe, Melissa ORCID: https://orcid.org/0009-0002-0739-1449, Pobiedonoscew, Yasmine ORCID: https://orcid.org/0009-0005-5885-6287, Claus, Rainer ORCID: https://orcid.org/0000-0003-2617-8766, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Oakes, Christopher C. ORCID: https://orcid.org/0000-0001-8000-9694, Zoldan, Katharina, Cross, Michael ORCID: https://orcid.org/0000-0002-8815-7621, Platzbecker, Uwe, Kneisel, Niclas ORCID: https://orcid.org/0009-0003-7502-8243, Raffel, Simon, Germing, Ulrich, Hoermann, Gregor, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Rippe, Karsten ORCID: https://orcid.org/0000-0001-9951-9395, Fröhling, Stefan, Pusch, Stefan ORCID: https://orcid.org/0000-0002-3407-4249, Plass, Christoph, Milsom, Michael D. ORCID: https://orcid.org/0000-0002-3567-254X and Lipka, Daniel B. ORCID: https://orcid.org/0000-0001-5081-7869
Blood 148
(7): 867-881.
13 August 2026
Supplementary Tables 1 - 27 from Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia.
Hartmann, Mark ORCID: https://orcid.org/0000-0002-4072-4658, Schönung, Maximilian ORCID: https://orcid.org/0000-0002-9778-9698, Rajak, Jovana ORCID: https://orcid.org/0009-0007-0229-8583, Maurer, Valentin ORCID: https://orcid.org/0000-0002-7670-0586, Hai, Ling ORCID: https://orcid.org/0000-0001-8719-2727, Bauer, Katharina, Hakobyan, Mariam ORCID: https://orcid.org/0000-0003-4719-5186, Stäble, Sina ORCID: https://orcid.org/0000-0002-5962-2440, Langstein, Jens ORCID: https://orcid.org/0009-0005-4284-0854, Jardine, Laura ORCID: https://orcid.org/0000-0003-4495-8205, Roelz, Roland ORCID: https://orcid.org/0000-0002-0985-7583, Bohler, Sheila ORCID: https://orcid.org/0000-0001-8860-9424, Khabirova, Eleonora ORCID: https://orcid.org/0000-0002-5891-6789, Maag, Abdul-Habib ORCID: https://orcid.org/0009-0008-5835-2910, Vonficht, Dominik ORCID: https://orcid.org/0000-0002-5579-7083, Lebrecht, Dirk ORCID: https://orcid.org/0000-0002-4483-2920, Bernt, Kathrin M. ORCID: https://orcid.org/0000-0002-0691-356X, Tan, Kai ORCID: https://orcid.org/0000-0002-9104-5567, Chen, Changya ORCID: https://orcid.org/0000-0003-4421-2462, Alikarami, Fatemeh ORCID: https://orcid.org/0000-0002-3600-9192, Meyer, Julia ORCID: https://orcid.org/0000-0001-5945-9885, Wang, Jun ORCID: https://orcid.org/0009-0005-6938-9821, Boch, Tobias ORCID: https://orcid.org/0000-0001-8588-4180, Flore, Viktoria ORCID: https://orcid.org/0009-0001-3023-433X, Lutsik, Pavlo ORCID: https://orcid.org/0000-0001-9383-8555, Milsom, Michael D. ORCID: https://orcid.org/0000-0002-3567-254X, Raffel, Simon ORCID: https://orcid.org/0000-0003-4671-1097, Buske, Christian ORCID: https://orcid.org/0000-0002-9782-9012, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Haniffa, Muzlifah ORCID: https://orcid.org/0000-0002-3927-2084, Mallm, Jan-Philipp ORCID: https://orcid.org/0000-0002-7059-4030, Behjati, Sam ORCID: https://orcid.org/0000-0002-6600-7665, Bonder, Marc-Jan ORCID: https://orcid.org/0000-0002-8431-3180, Fröhling, Stefan ORCID: https://orcid.org/0000-0001-7907-4595, Stieglitz, Elliot ORCID: https://orcid.org/0000-0001-7032-4623, Niemeyer, Charlotte M. ORCID: https://orcid.org/0000-0003-3856-7937, Hey, Joschka ORCID: https://orcid.org/0000-0003-2842-764X, Flotho, Christian ORCID: https://orcid.org/0000-0001-9367-0553, Plass, Christoph ORCID: https://orcid.org/0000-0003-2554-3952, Erlacher, Miriam ORCID: https://orcid.org/0000-0002-7261-1447, Schlesner, Matthias ORCID: https://orcid.org/0000-0002-5896-4086 and Lipka, Daniel B. ORCID: https://orcid.org/0000-0001-5081-7869
[Dataset]
4 March 2026
Molecular plasticity results in oncofetal reprogramming and therapeutic vulnerabilities in juvenile myelomonocytic leukemia.
Hartmann, Mark, Schönung, Maximilian, Rajak, Jovana, Maurer, Valentin, Hai, Ling, Bauer, Katharina, Hakobyan, Mariam, Stäble, Sina, Langstein, Jens, Jardine, Laura, Roelz, Roland, Bohler, Sheila, Khabirova, Eleonora, Maag, Abdul-Habib, Vonficht, Dominik ORCID: https://orcid.org/0000-0002-5579-7083, Lebrecht, Dirk, Bernt, Kathrin M., Tan, Kai, Chen, Changya, Alikarami, Fatemeh, Meyer, Julia, Wang, Jun, Boch, Tobias, Flore, Viktoria ORCID: https://orcid.org/0009-0001-3023-433X, Lutsik, Pavlo, Milsom, Michael D., Raffel, Simon, Buske, Christian, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Haniffa, Muzlifah, Mallm, Jan-Philipp, Behjati, Sam, Bonder, Marc-Jan, Fröhling, Stefan, Stieglitz, Elliot, Niemeyer, Charlotte M., Hey, Joschka, Flotho, Christian, Plass, Christoph, Erlacher, Miriam, Schlesner, Matthias and Lipka, Daniel B.
Blood Cancer Discovery 7
(2): 306-330.
1 March 2026
Tolerance to extracellular acidic pH facilitates tumor plasticity.
Hasegawa, Manami, Xu, Bo, Maeda, Keisuke, Seki, Motoaki, Cai, FeiFei, Cui, Runmei, Ando, Ritsuko, Nakagawa, Suzuka ORCID: https://orcid.org/0000-0002-9417-9499, Sakamoto, Ayana, Boycott, Cayla, Yatabe, Hiroyuki, Nishida, Miyuki, Matsumoto, Ken, Iwabuchi-Yoshida, Chisato, Aki, Sho, Yamagata, Kazuyuki, Tsuchida, Rika, Takahashi, Mami, Kuribayashi, Futoshi, Kidoya, Hiroyasu, Hirata, Hiroshi, Matsumoto, Shingo, Sando, Shinsuke, Yanai, Hideyuki, Yachie, Nozomu and Osawa, Tsuyoshi
Cell Reports
: 117226.
16 April 2026
(In Press)
Biological advances and current challenges for pediatric rhabdomyosarcoma.
Hebron, Katie E. ORCID: https://orcid.org/0000-0002-4740-8930, Odeniyide, Patience ORCID: https://orcid.org/0000-0002-9783-1657, Wei, Yun ORCID: https://orcid.org/0000-0003-2080-499X, Gryder, Berkley E. ORCID: https://orcid.org/0000-0003-0130-2302, Barr, Frederic G., Casey, Dana L., Chen, Eleanor Y. ORCID: https://orcid.org/0000-0003-4372-7560, Crompton, Brian D., Dela Cruz, Filemon S. ORCID: https://orcid.org/0000-0002-8356-5191, Durbin, Adam D. ORCID: https://orcid.org/0000-0002-5472-9847, Ford, Heide L., Gatz, Susanne A. ORCID: https://orcid.org/0000-0002-6438-9778, Hatley, Mark E. ORCID: https://orcid.org/0000-0001-7147-3946, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Hettmer, Simone ORCID: https://orcid.org/0000-0003-1709-4448, Houghton, Peter J., Kendall, Genevieve C. ORCID: https://orcid.org/0000-0003-3775-2006, Khan, Javed ORCID: https://orcid.org/0000-0002-5858-0488, Lupo, Philip J. ORCID: https://orcid.org/0000-0003-0978-5863, Patel, Anand G. ORCID: https://orcid.org/0000-0002-1438-8275, Pomella, Silvia ORCID: https://orcid.org/0000-0002-7007-4238, Rota, Rossella ORCID: https://orcid.org/0000-0002-9408-7711, Schito, Marco, Schoot, Reineke A., Shern, Jack F. ORCID: https://orcid.org/0000-0001-5579-7625, Stanton, Benjamin Z. ORCID: https://orcid.org/0000-0002-2613-2955, Stewart, Elizabeth A., Swindlehurst, Cathy A., Thomas, Craig J., Vakoc, Christopher R., Vaseva, Angelina V., Venkatramani, Rajkumar, Wexler, Leonard H., Yustein, Jason T., Hammond, Sharon, Heske, Christine M. ORCID: https://orcid.org/0000-0003-0956-6249, Langenau, David M., Linardic, Corinne M. ORCID: https://orcid.org/0000-0002-3257-2885, Ignatius, Myron S. and Yohe, Marielle E.
Cancers 18
(6): 888.
March 2026
Supplementation with short-chain fatty acids and a prebiotic improves clinical outcome in Parkinson’s disease: a randomized double-blind prospective study.
Hegelmaier, Tobias, Duscha, Alexander, Desel, Christiane, Fuchs, Sabrina, Shapira, Michal, Amidror, Sivan, Shan, Qihao, Stangl, Gabriele I., Hirche, Frank, Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299, Maifeld, András ORCID: https://orcid.org/0000-0001-8756-747X, Würtele, Lisa-Marie, Peplinski, Jana, Jauk, Diana, Naim, Gitali, Shidlovsky, Nuphar, Cohen, Adva, Bennet, Yifat, Paschold, Lisa, Dumitru, Claudia A., Obermüller-Jevic, Ute, Hustvedt, Svein-Olaf, Timmesfeld, Nina, Gold, Ralf, Zapf, Antonia, Binder, Mascha, Sandalcioglu, Ibrahim E., Mostaghim, Sanaz, Przuntek, Horst, Segal, Eran, Yissachar, Nissan and Haghikia, Aiden
Scientific Reports 16
(1): 315.
5 January 2026
MRD-2 in the GHSG HD21 trial assessed by a validated circulating tumor DNA sequencing assay.
Heger, Jan-Michel, Mattlener, Julia, Kaul, Helen, Ferdinandus, Justin, Schneider, Jessica, Schleifenbaum, Julia K., Schneider, Gundolf, Schaub, Valdete, Haenel, Mathias, Hellmuth, Johannes Christian, Dierlamm, Judith, Martin, Sonja, Mathas, Stephan ORCID: https://orcid.org/0000-0001-9626-1413, Meissner, Julia, Pegtel, D. Michiel, Zijlstra, Josée M., Ossowski, Anna, Becker, Kerstin, Hallek, Michael J., von Tresckow, Bastian, Borchmann, Peter and Borchmann, Sven
Blood 147
(19): 2194-2202.
7 May 2026
Genetic alterations of SENP6 in multiple myeloma disrupt genome and proteome stability, sensitizing to proteasome inhibition.
Herzberg, Frederik, Korenkov, Michael ORCID: https://orcid.org/0000-0002-2988-8483, Isaakidis, Konstandina, Zang, Chuanbing, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Müller, Stefan, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Demel, Uta M. ORCID: https://orcid.org/0000-0002-6480-4185
Haematologica 111
(5): 1828-1834.
May 2026
Functional immune profiling translates T cell dynamics into predictive biomarkers for myeloma immunotherapy.
Herzberg, Frederik, Lu, Feiteng ORCID: https://orcid.org/0000-0002-4782-9436, Korenkov, Michael ORCID: https://orcid.org/0000-0002-2988-8483, Fregona, Vincent ORCID: https://orcid.org/0000-0003-4857-1737, Didoss, Carin, Heisterkamp, Nina, Sprechert, Maximilian, Polici, Alexandra, Heck, Clarissa, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Krönke, Jan ORCID: https://orcid.org/0000-0002-4649-0506, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Bohl, Stephan R. ORCID: https://orcid.org/0000-0001-9379-3342
Leukemia 40
(9): 1997-2007.
September 2026
Targetable alterations and personalized treatment in ameloblastoma: results from a prospective observational precision oncology study.
Hofmann, Elena, Abu-Sirhan, Shady, Elsholtz, Fabian, Piwonski, Iris, Kreutzer, Kilian, Doll, Christian, Joosten, Maria, Möbs, Markus, Busch, Chia-Jung, Fenske, Benjamin, Knödler, Maren, Pestana, Ana, Hirschhorn, Ariel, Heiland, Max, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Keilholz, Ulrich, Klinghammer, Konrad ORCID: https://orcid.org/0000-0001-6425-4833, Rieke, Damian T. and Schmidt, Max
npj Precision Oncology 10
(1): 217.
12 June 2026
Single-cell mitochondrial genotyping of exonuclease-deficient DNA polymerase γ (POLGD274A) knock-in HEK293 cell lines.
Hsieh, Y.H. ORCID: https://orcid.org/0000-0003-3037-8728, Liebold, J. and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
[Dataset]
10 April 2026
Single-cell multi-omic analysis of mitochondrial mutational mosaicism and dynamics.
Hsieh, Yu-Hsin ORCID: https://orcid.org/0000-0003-3037-8728, Kautz, Pauline ORCID: https://orcid.org/0000-0002-9658-1676, Nitsch, Lena ORCID: https://orcid.org/0000-0003-0775-1969, Giguelay, Ambre M. ORCID: https://orcid.org/0000-0003-0417-1109, Liebold, Janet, Dimitrova, Veronika ORCID: https://orcid.org/0009-0007-6915-7136, Contreras Castillo, Stephania ORCID: https://orcid.org/0000-0002-5551-8697, Jungen, Freya ORCID: https://orcid.org/0009-0007-7857-701X, Zsurka, Gabor ORCID: https://orcid.org/0000-0002-6379-849X, Trombly, Genevieve, Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891, Kunz, Wolfram S. ORCID: https://orcid.org/0000-0003-1113-3493, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807 and Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164
Nature Communications 17
(1): 2532.
17 March 2026
Low reporting quality limits the contribution of human organ models to COVID-19 research: a systematic review.
Hülsemann, Maren ORCID: https://orcid.org/0000-0002-9344-0800, Kniffert, Silke ORCID: https://orcid.org/0000-0001-5084-3960, Löwa, Anna, Baumgardt, Morris, Hönzke, Katja, Vallone, Valeria Fernandez, Drude, Natascha I., Stüdemann, Thomas, Ali, Ahmed S.M., Arroyo Araujo, Maria, Bannach-Brown, Alexandra ORCID: https://orcid.org/0000-0002-3161-1395, Brunotte, Linda, Faist, Aileen ORCID: https://orcid.org/0000-0003-1446-9523, Fatykhova, Diana, Fischer, Mara ORCID: https://orcid.org/0000-0003-2674-8001, Hellwig, Lina, Hinse, Saskia, Kessler, Mirjana, Carlisle, Benjamin G., Khankeh, Sadaf, Dhamrait, Ishminder Singh ORCID: https://orcid.org/0000-0001-9713-9807, Klein, Charlotte, Koceva, Hristina ORCID: https://orcid.org/0000-0002-2915-7496, Kumar, Sriram ORCID: https://orcid.org/0000-0001-6464-1219, Kurreck, Jens, Ludwik, Katarzyna A. ORCID: https://orcid.org/0000-0002-9436-7270, Mergenthaler, Philipp ORCID: https://orcid.org/0000-0002-9753-6711, Schmerbeck, Sarah S., Singh, Sameer ORCID: https://orcid.org/0000-0001-6140-5501, Teixeira Alves, Luiz Gustavo ORCID: https://orcid.org/0000-0002-5822-4168, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Stachelscheid, Harald, Hippenstiel, Stefan, Toelch, Ulf and Hocke, Andreas C.
EBioMedicine 130
: 106392.
August 2026
High-dose chemotherapy followed by autologous stem-cell transplantation versus non-myeloablative consolidation in primary CNS lymphoma (MATRix/IELSG43): a randomised phase 3 trial.
Illerhaus, Gerald, Ferreri, Andrés J.M., Wendler, Julia, Binder, Mascha, Borchmann, Peter, Hasenkamp, Justin, Stilgenbauer, Stephan, Röth, Alexander, Egerer, Gerlinde, Ernst, Thomas, Weber, Thomas, Hertenstein, Bernd, Lenz, Georg, Dreyling, Martin, Möhle, Robert, Kobbe, Guido, Schmidt, Christian A., Brunnberg, Uta, Panse, Jens, Kneba, Michael, Heinicke, Thomas, Schroll, Sebastian, Larsen, Thomas S., Thurner, Lorenz, Pukrop, Tobias, Salwender, Hans, Naumann, Ralph, Hess, Georg, Kroschinsky, Frank P., Blystad, Anne K., Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Pulczynski, Elisa J., Pedersen, Martin Bjerregård, Re, Francesca, Orsucci, Lorella, Pospiech, Lisa, La Rosée, Paul, Deckert, Martina, Ponzoni, Maurilio, Gmehlin, Dennis, Backenstrass, Matthias, Jensch, Antje, Valk, Elke, Calimeri, Teresa, Kasenda, Benjamin, Trepel, Martin, Fricker, Heidi, Semenova, Inna, Scherer, Florian, von Gottberg, Philipp, Burger, Elvira, Grishina, Olga, Hader, Claudia, Ihorst, Gabriele, Finke, Jürgen, Zucca, Emanuele and Schorb, Elisabeth
Lancet 408
(10554): 532-544.
14 August 2026
Arrhythmic myocarditis and prevention of sudden cardiac death: current evidence, risk stratification, and management.
Imazio, Massimo ORCID: https://orcid.org/0000-0002-5722-0245, Collini, Valentino ORCID: https://orcid.org/0000-0003-0008-4630, Tomat, Mariacristina ORCID: https://orcid.org/0009-0009-4081-9559, Venturelli, Francesco ORCID: https://orcid.org/0009-0008-5512-0719, Spollero, Giorgia, Gröschel, Jan ORCID: https://orcid.org/0000-0002-7268-9041, Lazarou, Emilia ORCID: https://orcid.org/0000-0001-5943-2172, Schulz-Menger, Jeanette ORCID: https://orcid.org/0000-0003-3100-1092 and Lazaros, George ORCID: https://orcid.org/0000-0003-2802-9617
Hellenic Journal of Cardiology
7 July 2026
(In Press)
Sugar sweetened and artificially sweetened beverages, fruit and vegetable juices and cancer risk: a World Cancer Research Fund International Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis.
Jayedi, Ahmad ORCID: https://orcid.org/0000-0003-4231-3147, Markozannes, Georgios ORCID: https://orcid.org/0000-0001-8481-579X, Kazmi, Sayada Zartasha ORCID: https://orcid.org/0000-0002-9267-3637, Cariolou, Margarita ORCID: https://orcid.org/0000-0003-2660-7866, Vieira, Rita, Kiss, Sonia, Balducci, Katia, Pagkalidou, Eirini ORCID: https://orcid.org/0000-0002-8655-7293, Cividini, Sofia ORCID: https://orcid.org/0000-0003-2705-9224, Aune, Dagfinn ORCID: https://orcid.org/0000-0002-4533-1722, Greenwood, Darren C. ORCID: https://orcid.org/0000-0001-7035-3096, Dossus, Laure ORCID: https://orcid.org/0000-0003-2716-5748, Fontvieille, Emma ORCID: https://orcid.org/0000-0001-5488-9317, Ahmadi, Nahid ORCID: https://orcid.org/0000-0001-8144-2764, Mahamat-Saleh, Yahya ORCID: https://orcid.org/0000-0002-5892-8886, Cross, Amanda J. ORCID: https://orcid.org/0000-0002-0893-2377, Gunter, Marc J. ORCID: https://orcid.org/0000-0001-5472-6761, Zürn, Shalini Jayasekar, Abnet, Christian C. ORCID: https://orcid.org/0000-0002-3008-7843, Ferrari, Pietro ORCID: https://orcid.org/0000-0001-9358-7338, Gordon-Dseagu, Vanessa L.Z. ORCID: https://orcid.org/0000-0003-1867-2238, Maskell, Kristy, Clary, Christelle ORCID: https://orcid.org/0000-0001-5959-5043, Croker, Helen ORCID: https://orcid.org/0000-0002-7247-6599, Mitrou, Panagiota, Riboli, Elio ORCID: https://orcid.org/0000-0001-6795-6080, Baskin, Monica ORCID: https://orcid.org/0000-0002-5544-0412, Chowdhury, Rajiv ORCID: https://orcid.org/0000-0003-4881-5690, Gaudet, Mia ORCID: https://orcid.org/0000-0002-6429-4007, Giovannucci, Edward ORCID: https://orcid.org/0009-0003-9117-569X, Kampman, Ellen ORCID: https://orcid.org/0000-0002-8606-7075, Lewis, Sarah J. ORCID: https://orcid.org/0000-0003-4311-6890, May, Anne M., Park, Yikyung ORCID: https://orcid.org/0000-0002-6281-489X, Pischon, Tobias ORCID: https://orcid.org/0000-0003-1568-767X, Severi, Gianluca, Hill, Lynette, Weijenberg, Matty P. ORCID: https://orcid.org/0000-0003-1695-4768, Krebs, John, Tsilidis, Konstantinos K. and Chan, Doris S.M. ORCID: https://orcid.org/0000-0002-0198-1897
medRxiv
: 2026.06.22.26355879.
1 July 2026
TOPAS: phosphoproteome data analysis and decision support platform for molecular tumor boards.
Jensen, Cecilia Bang, Sakhteman, Amirhossein, Hamood, Firas, Schneider, Annika, Woortman, Julia, Teleanu, Maria-Veronica, Horak, Peter, Bayer, Florian P., Stange, Christoph, Huellein, Jennifer, Hübschmann, Daniel, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Fröhling, Stefan, Kuster, Bernhard and The, Matthew
bioRxiv
: 2026.07.08.737143.
13 July 2026
Supplementary Data 1 from The Histone Modifier KANSL2 Is an Actionable Biomarker in Multiple Myeloma.
Jiang, Kaiting, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Herzberg, Frederik, Zhao, Yan, Gasper, Amelie, Baumgartner, Francis ORCID: https://orcid.org/0000-0003-0768-1956, Jung, Paul, Braune, Jan, Schulze, Veronika, Isaakidis, Konstandina, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Krönke, Jan, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Habringer, Stefan ORCID: https://orcid.org/0000-0002-3976-9592
[Dataset]
1 June 2026
(Submitted)
Supplementary Data 2 from The Histone Modifier KANSL2 Is an Actionable Biomarker in Multiple Myeloma.
Jiang, Kaiting, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Herzberg, Frederik, Zhao, Yan, Gasper, Amelie, Baumgartner, Francis ORCID: https://orcid.org/0000-0003-0768-1956, Jung, Paul, Braune, Jan, Schulze, Veronika, Isaakidis, Konstandina, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Krönke, Jan, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Habringer, Stefan ORCID: https://orcid.org/0000-0002-3976-9592
[Dataset]
1 June 2026
(Submitted)
Supplementary Data 3 from The Histone Modifier KANSL2 Is an Actionable Biomarker in Multiple Myeloma.
Jiang, Kaiting, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Herzberg, Frederik, Zhao, Yan, Gasper, Amelie, Baumgartner, Francis ORCID: https://orcid.org/0000-0003-0768-1956, Jung, Paul, Braune, Jan, Schulze, Veronika, Isaakidis, Konstandina, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Krönke, Jan, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Habringer, Stefan ORCID: https://orcid.org/0000-0002-3976-9592
[Dataset]
1 June 2026
(Submitted)
Supplementary Data 4 from The Histone Modifier KANSL2 Is an Actionable Biomarker in Multiple Myeloma.
Jiang, Kaiting, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Herzberg, Frederik, Zhao, Yan, Gasper, Amelie, Baumgartner, Francis ORCID: https://orcid.org/0000-0003-0768-1956, Jung, Paul, Braune, Jan, Schulze, Veronika, Isaakidis, Konstandina, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Krönke, Jan, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Habringer, Stefan ORCID: https://orcid.org/0000-0002-3976-9592
[Dataset]
1 June 2026
(Submitted)
The histone modifier KANSL2 is an actionable biomarker in multiple myeloma.
Jiang, Kaiting ORCID: https://orcid.org/0009-0000-3282-5953, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Herzberg, Frederik ORCID: https://orcid.org/0009-0000-7338-7849, Zhao, Yan ORCID: https://orcid.org/0000-0002-3087-4767, Gasper, Amelie ORCID: https://orcid.org/0009-0003-5247-9498, Baumgartner, Francis ORCID: https://orcid.org/0000-0003-0768-1956, Jung, Paul ORCID: https://orcid.org/0000-0002-6447-450X, Braune, Jan ORCID: https://orcid.org/0000-0003-2026-2641, Schulze, Veronika ORCID: https://orcid.org/0009-0004-0823-1660, Isaakidis, Konstandina ORCID: https://orcid.org/0009-0002-7451-6889, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Krönke, Jan ORCID: https://orcid.org/0000-0002-4649-0506, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Habringer, Stefan ORCID: https://orcid.org/0000-0002-3976-9592
Molecular Cancer Therapeutics 25
(6): 1016-1029.
1 June 2026
3-hydroxypropionyl-CoA Synthetase (ADP-forming) from Nitrosopumilus maritimus.
Johnson, J.A., Yilmaz, M., Tosun, B., Wakatsuki, S. and Demirci, H.
[Dataset]
11 March 2026
Crystal structure of 3-hydroxypropionyl-CoA synthetase (ADP-forming) from Nitrosopumilus maritimus.
Johnson, Jerome, Tosun, Bilge, Yilmaz, Merve, Tolar, Bradley B., Yoshikuni, Yasuo, Francis, Christopher A., Doukov, Tzanko, Yokoi, Shun, Wakatsuki, Soichi and DeMirci, Hasan
Current Research in Structural Biology 11
: 100189.
June 2026
Fecal detection of calprotectin subunits links inflammatory bowel disease activity with chronicity of intestinal inflammation.
Jukic, Almina, Hilbe, Richard, Zundel, Luis, Willeit, Peter, Faserl, Klaus, Plattner, Christina, Zollner, Andreas, Meyer, Moritz, Siegmund, Kerstin, Klepsch, Victoria, Marteau, Valentin, Vich Vila, Arnau, Schwärzler, Julian, Vouk, Kathrin, Kozsar, Anna, Rieder, Dietmar, Weichberger, Amos, Sarg, Bettina, Grabherr, Felix, Mayr, Lisa, Moser, Patrizia, Nemati, Niloofar, Scholl-Bürgi, Sabine, Karall, Daniela, Vogel, Georg F., Welz, Lina, Aldrian, Denise, Koch, Robert, Pfister, Alexandra, Ran, Qitao, Kaser, Arthur, Blumberg, Richard S., Tancevski, Ivan, Sommer, Felix, Bacher, Petra, Schreiber, Stefan, Rosenstiel, Philip, Aden, Konrad, Baier, Gottfried, Bakiri, Latifa, Müller, Thomas, Weiss, Günter, Weersma, Rinse K., Trajanoski, Zlatko, Wagner, Erwin F., Tilg, Herbert and Adolph, Timon E.
Gastroenterology 170
(3): 523-538.
March 2026
Phylogenetic analysis of paired breast carcinomas identifies genetic events associated with clonal recurrence and invasive progression.
Kader, Tanjina ORCID: https://orcid.org/0000-0002-1463-7593, Zethoven, Maia, Mahale, Sakshi, Saunders, Hugo, Tjoeka, Lauren ORCID: https://orcid.org/0009-0008-4320-6267, Lehmann, Rebecca, Jayawardana, Madawa W., Pang, Jia-Min ORCID: https://orcid.org/0000-0002-3466-7431, Lesche, Dorothea, Rajan, Neeha, Semple, Timothy, Lee, Jue Er Amanda, Lupat, Richard, Byrne, David J., Hughes, Siobhan, Nguyen, Hoa, Lai, Siqi, Pechlivanis, Maree, Craig, Olivia, Devereux, Lisa, House, Eloise, Jayasinghe, Sureshni I., Kaufmann, Tom L. ORCID: https://orcid.org/0000-0003-4374-1338, Schwarz, Roland F. ORCID: https://orcid.org/0000-0001-9155-4268, Green, Andrew R. ORCID: https://orcid.org/0000-0002-0488-5913, Miligy, Islam M., Cummings, Margaret, Lakhani, Sunil, Campbell, Ian G. ORCID: https://orcid.org/0000-0002-7773-4155, Rakha, Emad, Fox, Stephen B. ORCID: https://orcid.org/0000-0002-7648-8896, Mann, G. Bruce and Gorringe, Kylie L. ORCID: https://orcid.org/0000-0001-5681-2022
Journal of Pathology 268
(1): 1-12.
January 2026
An integrated landscape of mRNA and protein isoforms.
Kedan, Amir, Zauber, Henrik ORCID: https://orcid.org/0000-0003-2595-1147, Wang, Meng-Ran, Kim, Suyeon, Zhu, Qionghua, Fang, Liang, Lilley, Kathryn S., Chen, Wei ORCID: https://orcid.org/0000-0003-3263-1627 and Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751
Cell Reports 45
(9): 117898.
22 September 2026
An ultrasensitive spatial tissue proteomics workflow exceeding 100 proteomes per day.
Klingeberg, Melissa ORCID: https://orcid.org/0009-0002-4778-2874, Krisp, Christoph ORCID: https://orcid.org/0000-0002-4689-1967, Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Schallenberg, Simon, Hornburg, Daniel ORCID: https://orcid.org/0000-0002-6618-7774 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
Molecular & Cellular Proteomics 25
(1): 101489.
January 2026
Patient-specific B-cell lymphoma modeling identifies cooperating genetic alterations and the critical influence of patient context.
Konrath, Fabian ORCID: https://orcid.org/0000-0002-6843-6252, Denker, Sophy ORCID: https://orcid.org/0000-0002-0736-6019, Schmitt, Clemens ORCID: https://orcid.org/0000-0002-4731-2226, Chapuy, Björn ORCID: https://orcid.org/0000-0002-6485-8773 and Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868
Research Square
: rs.3.rs-9022766/v1.
12 March 2026
BCMA-targeted T-cell engager therapy induces sustained remission in immune thrombocytopenia.
Korenkov, Michael ORCID: https://orcid.org/0000-0002-2988-8483, Zuleeg, Maximilian Rudolf ORCID: https://orcid.org/0009-0002-9947-5585, Liebaert, Julian, Fregona, Vincent ORCID: https://orcid.org/0000-0003-4857-1737, Serve, Sebastian ORCID: https://orcid.org/0000-0002-9839-7119, Jesse, Julia, Böckle, Stephan Rainer ORCID: https://orcid.org/0000-0002-1783-9641, Bohl, Stephan Rainer ORCID: https://orcid.org/0000-0001-9379-3342, Damm, Frederik ORCID: https://orcid.org/0000-0001-5553-1173, Bullinger, Ulrich ORCID: https://orcid.org/0000-0002-5890-5510, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Busse, Adrian ORCID: https://orcid.org/0000-0002-3470-6947, Schwarzer, Adrian, Albach, Fredrik ORCID: https://orcid.org/0000-0002-2697-9080, Thiele, Thomas ORCID: https://orcid.org/0000-0003-0177-6508, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Krönke, Jan ORCID: https://orcid.org/0000-0002-4649-0506 and Hütter-Krönke, Marie Luise ORCID: https://orcid.org/0000-0002-4531-9889
Blood Immunology & Cellular Therapy 2
(3): 100062.
September 2026
Unpaired data as a first-order challenge in single-cell and spatial proteomics.
Koutrouli, Mikaela, Finotello, Francesca, Schoof, Erwin M. ORCID: https://orcid.org/0000-0002-3117-7832 and Roussos, Panos ORCID: https://orcid.org/0000-0002-4640-6239
Nature Biotechnology 44
(6): 891-892.
June 2026
Clonal Hematopoiesis does not influence manufacturing of Chimeric Antigen Receptor (CAR) T-Cells.
Krauß, Simon M. ORCID: https://orcid.org/0009-0009-8514-5500, Weibl, Konstantin, Bach, Enrica, Brückner, Mandy, Weigert, Anne, Tumewu, Theresa, Ruschpler, Elena, Vogtmann, Gunhild, Hoffmann, Sandra, Penack, Olaf ORCID: https://orcid.org/0000-0003-4876-802X, Janz, Martin ORCID: https://orcid.org/0000-0002-1127-0044, Buhmann, Raymund, Henschler, Reinhard, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Schwind, Sebastian ORCID: https://orcid.org/0000-0002-1315-2332, Merz, Maximilian, Jentzsch, Madlen ORCID: https://orcid.org/0000-0002-2270-0804, Franke, Georg-Nikolaus ORCID: https://orcid.org/0000-0001-8239-002X, Herling, Marco, Platzbecker, Uwe ORCID: https://orcid.org/0000-0003-1863-3239, Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 and Vučinić, Vladan ORCID: https://orcid.org/0000-0002-8398-285X
Bone Marrow Transplantation 61
(8): 1105-1107.
August 2026
Spatial and phenotypic heterogeneity of ILC subsets in mouse lung under type 2 inflammatory conditions.
Kroh, Sandy ORCID: https://orcid.org/0000-0002-3736-3361, Pascual-Reguant, Anna ORCID: https://orcid.org/0000-0002-5042-3699, Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Uecker, Ralf, Günther, Robert, Philipsen, Lars ORCID: https://orcid.org/0000-0001-5112-495X, Koehler, Ralf ORCID: https://orcid.org/0000-0002-3660-1196, Mex, Peggy ORCID: https://orcid.org/0009-0005-7567-1313, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Niesner, Raluca A. ORCID: https://orcid.org/0000-0001-8969-5432 and Hauser, Anja E. ORCID: https://orcid.org/0000-0002-7725-9526
European Journal of Immunology 56
(6): e70223.
June 2026
Introducing Mikhail Kudryashev, Clorice R. Reinhardt, Alec H. Follmer, and Michael C. Thompson.
Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274, Reinhardt, Clorice R., Follmer, Alec H. and Thompson, Michael C.
Structure 34
(5): 681-684.
7 May 2026
Targeting mutual dependence of phosphatidylinositol-3-kinase α/δ and small ubiquitin-like modifier signaling in pancreatic cancer.
Köse, Hazal, Schneeweis, Christian, Putze, Philipp, Contreras, Constanza Tapia, Ferreiro, Laura, Witte, Leonie, Deidda, Ilaria, Herzberg, Frederik, Ebert, Sophie, Jakubik, Juraj, Moldaner, Leoni, Todorovic, Jovan, Träger, Isabelle, Zang, Chuanbing, Demel, Uta M. ORCID: https://orcid.org/0000-0002-6480-4185, Hessmann, Elisabeth, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Rhein, Simone ORCID: https://orcid.org/0000-0002-9445-2352, Hoffmann, Jens ORCID: https://orcid.org/0000-0003-3880-1658, Tatarova, Zuzana, Ghadimi, Michael, Saur, Dieter, Kappert, Kai, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Schneider, Günter, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872
Gastroenterology 170
(2): 315-329.
February 2026
Stimulation of Adult Muscle Stem Cells with BMPs Results in Direct Activation of Notch Pathway Genes [CUT&Tag].
Lange, B.K., Huryn, V. ORCID: https://orcid.org/0009-0009-1691-4919 and Schuelke, M. ORCID: https://orcid.org/0000-0003-2824-3891
[Dataset]
17 August 2026
Stimulation of Adult Muscle Stem Cells with BMPs Results in Direct Activation of Notch Pathway Genes.
Lange, B.K., Polydorou, I., Huryn, V. ORCID: https://orcid.org/0009-0009-1691-4919, Amthor, H. and Schuelke, M. ORCID: https://orcid.org/0000-0003-2824-3891
[Dataset]
17 August 2026
Extensive Crosstalk between BMP and Notch Signaling Pathways in Activated Adult Muscle Stem Cells.
Lange, Birthe ORCID: https://orcid.org/0000-0001-8538-7344, Huryn, Viktoriia ORCID: https://orcid.org/0009-0009-1691-4919 and Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891
[Dataset]
16 July 2026
Stimulation of adult muscle stem cells with BMPs results in direct activation of notch pathway genes.
Lange, Birthe Katrin Alexandra ORCID: https://orcid.org/0000-0001-8538-7344, Polydorou, Ioanna, Huryn, Viktoriia ORCID: https://orcid.org/0009-0009-1691-4919, Georgieva, Angelina M. ORCID: https://orcid.org/0000-0002-3215-427X, You, Shanshan, Müller, Thomas, Morales-Gonzalez, Susanne ORCID: https://orcid.org/0000-0001-7279-2092, Brandt, Bettina, Birchmeier, Carmen ORCID: https://orcid.org/0000-0002-2041-8872, Amthor, Helge and Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891
Cells 15
(16): 1490.
August 2026
Extensive crosstalk between BMP and notch signaling pathways in activated adult muscle stem cells.
Lange, Birthe Katrin Alexandra ORCID: https://orcid.org/0000-0001-8538-7344, Polydorou, Ioanna, Huryn, Viktoriia ORCID: https://orcid.org/0009-0009-1691-4919, Morales-Gonzalez, Susanne ORCID: https://orcid.org/0000-0001-7279-2092, Brandt, Bettina, Birchmeier, Carmen ORCID: https://orcid.org/0000-0002-2041-8872, Amthor, Helge and Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891
Preprints.org
: 202603.1228.
16 March 2026
Artefacts in single-cell mtDNA analyses misinform phylogenies.
Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Chapman, Michael Spencer, Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Nawy, Tal, Pe'er, Dana and Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164
Nature 656
(8128): E25-E31.
20 August 2026
A comprehensive review of cancer-induced cardiac wasting.
Lena, Alessia, Khan, Muhammad Shahzeb, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Modest, Dominik P. and Anker, Markus S.
British Journal of Pharmacology
22 April 2026
(In Press)
Quantification of the effects of single nucleotide variants in NKX2.1 transcription factor binding sites.
Lenihan-Geels, Freyda ORCID: https://orcid.org/0000-0002-4984-674X, Proft, Sebastian, Bommer, Martin ORCID: https://orcid.org/0000-0003-3195-9129, Heinemann, Udo ORCID: https://orcid.org/0000-0002-8191-3850, Seelow, Dominik ORCID: https://orcid.org/0000-0002-9746-4412, Opitz, Robert ORCID: https://orcid.org/0000-0003-3143-0997, Krude, Heiko ORCID: https://orcid.org/0000-0002-1169-0348, Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891 and Małecka, Maria ORCID: https://orcid.org/0000-0001-8339-3230
bioRxiv
: 2026.02.27.708450v2.
2 March 2026
Characterization of intestinal immune responses in generalized human and murine lipodystrophy.
Letizia, Marilena, Omar, Toka, Weidner, Patrick ORCID: https://orcid.org/0000-0003-2448-5981, Jakob, Manuel O., Freise, Inka, Krug, Susanne M., Löscher, Britt-Sabina, Rosati, Elisa, Obermayer, Benedikt, Gamez-Belmonte, Reyes, Hecker, Julia, Ziegler, Jörn-Felix, Weixler, Benjamin, Asbach, Patrick, Kunkel, Desiree, Stumvoll, Michael, Miehle, Konstanze, Becker, Christoph, Klose, Christoph S.N., Glauben, Rainer, Beule, Dieter, Kühl, Anja A, Conrad, Thomas, Tacke, Frank, Wirtz, Stefan, Franke, Andre, Sanders, Ashley D. ORCID: https://orcid.org/0000-0003-3945-0677, Siegmund, Britta and Weidinger, Carl
Journal of Clinical Investigation 136
(6): e192322.
16 March 2026
DeBCR: a sparsity-efficient framework for image enhancement through a deep-learning-based solution to inverse problems.
Li, Rui ORCID: https://orcid.org/0000-0002-3085-5267, Yushkevich, Artsemi ORCID: https://orcid.org/0000-0002-8729-9281, Chu, Xiaofeng ORCID: https://orcid.org/0000-0001-6801-3949, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Yakimovich, Artur ORCID: https://orcid.org/0000-0003-2458-4904
Communications Engineering 5
(1): 25.
10 February 2026
Cryo-SWAN: the Multi-Scale Wavelet-decomposition-inspired Autoencoder Network for molecular density representation of molecular volumes.
Li, Rui ORCID: https://orcid.org/0000-0002-3085-5267, Yushkevich, Artsemi ORCID: https://orcid.org/0000-0002-8729-9281, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Yakimovich, Artur
arXiv
: 2603.03342.
18 February 2026
Feasibility and safety of rapid glofitamab ramp-up.
Liem, Celine H. ORCID: https://orcid.org/0009-0000-6597-9692, Wurm-Kuczera, Rebecca, Böckle, David, Neumann, Marie Anne-Catherine, Teichert, Marcel, Novak, Urban ORCID: https://orcid.org/0000-0001-7642-2101, Klein Helmkamp, Merle, Shumilov, Evgenii ORCID: https://orcid.org/0000-0003-0178-1729, Malburg, Nina, Versteegen, Tim, Görke, Fabian, Magno, Giulia ORCID: https://orcid.org/0009-0008-6006-4758, Ghandili, Susanne ORCID: https://orcid.org/0000-0001-5655-3155, Kauer, Joseph ORCID: https://orcid.org/0000-0003-1632-0167, Christofyllakis, Konstantinos, Melchardt, Thomas, Dreger, Peter ORCID: https://orcid.org/0000-0002-7429-8570, Ayuk, Francis ORCID: https://orcid.org/0000-0001-6297-1847, Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469, Vučinić, Vladan ORCID: https://orcid.org/0000-0002-8398-285X, Pott, Christiane ORCID: https://orcid.org/0009-0005-9260-8340, Reinhardt, Hans Christian ORCID: https://orcid.org/0000-0001-5706-9349, Lenz, Georg ORCID: https://orcid.org/0000-0002-4728-1693, von Tresckow, Bastian ORCID: https://orcid.org/0000-0003-1410-4487, Pabst, Thomas ORCID: https://orcid.org/0000-0002-6055-5257, Borchmann, Peter, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958 and Chapuy, Björn
Leukemia 40
(9): 2033-2038.
September 2026
Safety and efficacy of a sandwich total neoadjuvant therapy strategy for low-risk distal locally advanced rectal cancer: results from the TESS phase II trial.
Liu, Shuang ORCID: https://orcid.org/0000-0003-2347-413X, Lv, GuangZhao, Xu, GeYu, Wang, XiaoZhong, Zhuang, YeZhong, Bai, ShouMin, Yu, HaiNa, Wu, XiaoJun, Ye, YiJing, Luo, HuiLong, Xu, ShuoYu, Wang, QiaoXuan, Chang, Hui, Cai, PeiQiang, Pan, ZhiZhong, Gao, YuanHong, Chen, Gong and Xiao, WeiWei
MedComm 7
(7): e70807.
July 2026
Clonal lineage tracing of innate immune cells in human cancer.
Liu, Vincent, Sandor, Katalin, Yan, Patrick K., Miao, Zhuang, Yin, Yajie, Stickels, Robert R., Chen, Andy Y., Hiam-Galvez, Kamir, Gutierrez, Jacob, Zhang, Wenxi, Sajjath, Sairaj M., Valbuena, Raeline, Wang, Steven, Daniel, Bence, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Howitt, Brooke E., Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807 and Satpathy, Ansuman T.
Cancer Cell 44
(7): 1509-1521.
13 July 2026
YAP1 enhances mesenchymal-type gene expression in human adrenergic-type neuroblastoma cells.
Ludwig, Marius ORCID: https://orcid.org/0000-0002-7000-6040, Ahrens, Kerstin, Winkler, Annika ORCID: https://orcid.org/0009-0007-9434-3862, Wünschel, Jasmin ORCID: https://orcid.org/0009-0007-5658-7532, Ruka, Peris, Lodrini, Marco ORCID: https://orcid.org/0000-0003-4434-529X, Hertwig, Falk ORCID: https://orcid.org/0000-0003-4784-6516, Castelli, Sveva ORCID: https://orcid.org/0000-0001-7660-5354, Thole-Kliesch, Theresa M. ORCID: https://orcid.org/0000-0003-2714-6221, Hollander, Jan F. ORCID: https://orcid.org/0009-0001-2907-2206, Fuchs, Steffen ORCID: https://orcid.org/0000-0001-9619-4329, Künkele, Annette ORCID: https://orcid.org/0000-0002-8406-5412, Jens, Marvin ORCID: https://orcid.org/0000-0002-6660-8743, Mamlouk, Soulafa ORCID: https://orcid.org/0000-0001-7285-1320, Warmann, Steven W. ORCID: https://orcid.org/0009-0001-2282-2780, Astrahantseff, Kathy ORCID: https://orcid.org/0000-0002-7872-1997, Eggert, Angelika, Schulte, Johannes H. ORCID: https://orcid.org/0000-0003-0671-1201, Szymansky, Annabell ORCID: https://orcid.org/0000-0003-4797-4526 and Deubzer, Hedwig E. ORCID: https://orcid.org/0000-0002-6115-4893
Cancers 18
(3): 383.
February 2026
Clade 2.3.4.4b H5N1 influenza A virus exhibits high infectivity in human respiratory tract models.
Löwa, Anna, Budt, Matthias, Balázs, Anita, Sikora, Victor, Melzer, Mark ORCID: https://orcid.org/0009-0006-3573-0531, Rubil, Tihomir, Pfeiffer, Annika E., Fischer, Mara, Mieth, Maren, Hellwig, Katharina, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Diel, Diego G., Tönnies, Mario, Bauer, Torsten T., Graff, Mareike, Neudecker, Jens, Rückert, Jens-C., Mall, Marcus A., Gruber, Achim D., Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Buchauer, Lisa, Hippenstiel, Stefan, Wolff, Thorsten and Hocke, Andreas C.
Journal of Infection 92
(5): 106722.
May 2026
Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Makhmut, Anuar ORCID: https://orcid.org/0009-0009-6913-4289, Dragomir, Mihnea P., Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Moebs, Markus ORCID: https://orcid.org/0000-0002-1502-3032, Schmitt, Wolfgang D. ORCID: https://orcid.org/0000-0002-7870-138X, Taube, Eliane T. ORCID: https://orcid.org/0000-0003-3041-694X and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
Molecular Systems Biology 22
(1): 7-41.
2 January 2026
Crystal structure of the NKX2.1 homeodomain in complex with a 12-bp DNA duplex containing a CAAG motif.
Malecka, M.Z. ORCID: https://orcid.org/0000-0001-8339-3230, Bommer, M. ORCID: https://orcid.org/0000-0003-3195-9129 and Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850
[Dataset]
20 May 2026
Crystal structure of the NKX2.1 homeodomain in complex with a 12-bp DNA duplex containing a CACG motif variant.
Malecka, M.Z. ORCID: https://orcid.org/0000-0001-8339-3230, Bommer, M. ORCID: https://orcid.org/0000-0003-3195-9129 and Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850
[Dataset]
11 March 2026
2nd SpatialData hackathon: frameworks, formats and interoperability.
Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Marconato, Luca ORCID: https://orcid.org/0000-0003-3198-1326, Albert, Marvin ORCID: https://orcid.org/0000-0003-2536-2545, Barnes, Chris ORCID: https://orcid.org/0000-0002-1296-7310, Blume, Alexander ORCID: https://orcid.org/0000-0003-3045-8234, Cerrone, Lorenzo ORCID: https://orcid.org/0000-0001-7337-2313, Crowell, Helena L. ORCID: https://orcid.org/0000-0002-4801-1767, Drummer, Francesca ORCID: https://orcid.org/0009-0002-7156-9125, Gruson, Hugo ORCID: https://orcid.org/0000-0002-4094-1476, Hess, Max ORCID: https://orcid.org/0000-0001-9528-4445, Hu, Taobo ORCID: https://orcid.org/0009-0009-2596-7588, Kedziora, Katarzyna ORCID: https://orcid.org/0000-0001-6524-7731, Kollotzek, Aaron ORCID: https://orcid.org/0009-0009-7142-4015, Macrí, Silvia Maria ORCID: https://orcid.org/0009-0009-2075-8699, Moerth, Eric ORCID: https://orcid.org/0000-0003-1625-0146, Moustafa, Samir ORCID: https://orcid.org/0000-0002-0674-9667, Ozleyen, Selman ORCID: https://orcid.org/0009-0009-2596-7588, Todd, Peter, Sarigün, Ahmet ORCID: https://orcid.org/0009-0003-2715-5344, Stockhaus, Sonja ORCID: https://orcid.org/0009-0005-7712-8154, Varrone, Marco ORCID: https://orcid.org/0000-0002-0538-3464, Vierdag, Wouter Michiel ORCID: https://orcid.org/0000-0003-1666-5421, Zappia, Luke ORCID: https://orcid.org/0000-0001-7744-8565, Zheng, Yimin ORCID: https://orcid.org/0000-0002-0394-9735, Stegle, Oliver ORCID: https://orcid.org/0000-0002-8818-7193 and Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117
BioHackrXiv
: s6bph_v2.
29 June 2026
Unraveling the single-cell spatial landscapes of melanoma brain metastases.
Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Peters, Kristin, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Fusco, Federico, Geserick, Felicitas, Rossner, Florian, Lehmann, Annika, Kleo, Karsten ORCID: https://orcid.org/0000-0001-9136-6902, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117, Jürchott, Karsten, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Delbridge, Claire, Sendler, Matthias, Radke, Josefine ORCID: https://orcid.org/0000-0001-9860-2007 and Redmer, Torben ORCID: https://orcid.org/0000-0002-0050-9478
medRxiv
: 2025.08.29.25334740v3.
3 June 2026
Number of affected lymph nodes predicts outcome in extremity rhabdomyosarcoma.
Margotte, Luna, Henssen, Anton ORCID: https://orcid.org/0000-0003-1534-778X, Thorwarth, Anne, Eggert, Angelika and Scheer, Monika ORCID: https://orcid.org/0000-0002-0665-6268
European Journal of Surgical Oncology 52
(3): 110535.
March 2026
Haplotype-resolved genome architecture mapping uncovers pervasive structural heterogeneity between human homologous chromosomes.
Markowski, Julia ORCID: https://orcid.org/0000-0002-0573-7832, Kukalev, Alexander ORCID: https://orcid.org/0000-0001-5847-3773, Robens, Claudia ORCID: https://orcid.org/0009-0008-6712-8953, Thieme, Christoph J. ORCID: https://orcid.org/0000-0002-1566-0971, Streck, Adam ORCID: https://orcid.org/0000-0002-7302-0147, Mao, Hui, Parsi, Krishna Mohan, Maehr, René, Pombo, Ana ORCID: https://orcid.org/0000-0002-7493-6288 and Schwarz, Roland F. ORCID: https://orcid.org/0000-0001-9155-4268
bioRxiv
: 2026.06.16.732681.
18 June 2026
Sedentary behaviour and cancer risk: a World Cancer Research Fund International Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis.
Markozannes, Georgios ORCID: https://orcid.org/0000-0001-8481-579X, Jayedi, Ahmad ORCID: https://orcid.org/0000-0003-4231-3147, Cariolou, Margarita ORCID: https://orcid.org/0000-0003-2660-7866, Pagkalidou, Eirini ORCID: https://orcid.org/0000-0002-8655-7293, Kazmi, Sayada Zartasha ORCID: https://orcid.org/0000-0002-9267-3637, Balducci, Katia, Kiss, Sonia, Vieira, Rita, Cividini, Sofia ORCID: https://orcid.org/0000-0003-2705-9224, Aune, Dagfinn ORCID: https://orcid.org/0000-0002-4533-1722, Greenwood, Darren C. ORCID: https://orcid.org/0000-0001-7035-3096, Cross, Amanda J., Gunter, Marc J. ORCID: https://orcid.org/0000-0001-5472-6761, Zürn, Shalini Jayasekar, Abnet, Christian C. ORCID: https://orcid.org/0000-0002-3008-7843, Gordon-Dseagu, Vanessa L.Z., Maskell, Kristy, Clary, Christelle, Croker, Helen ORCID: https://orcid.org/0000-0002-7247-6599, Mitrou, Panagiota, Riboli, Elio ORCID: https://orcid.org/0000-0001-6795-6080, Baskin, Monica, Chowdhury, Rajiv ORCID: https://orcid.org/0000-0003-4881-5690, Gaudet, Mia, Giovannucci, Edward, Kampman, Ellen, Lewis, Sarah J. ORCID: https://orcid.org/0000-0003-4311-6890, May, Anne M., Park, Yikyung ORCID: https://orcid.org/0000-0002-6281-489X, Pischon, Tobias ORCID: https://orcid.org/0000-0003-1568-767X, Severi, Gianluca ORCID: https://orcid.org/0000-0001-7157-419X, Hill, Lynette, Weijenberg, Matty P. ORCID: https://orcid.org/0000-0003-1695-4768, Krebs, John, Tsilidis, Konstantinos K. and Chan, Doris S.M. ORCID: https://orcid.org/0000-0002-0198-1897
medRxiv
: 2026.06.23.26355971.
29 June 2026
Identification of MHC ligands through allele-guided isolation combined with machine learning for improved MHC assignment using ARDisplay-I.
Mecklenbräuker, Shima, Skoczylas, Piotr, Biernat, Paweł ORCID: https://orcid.org/0000-0003-1482-9621, Zaghla, Badeel K.H.Q. ORCID: https://orcid.org/0009-0002-2675-8859, Atay, Bilge ORCID: https://orcid.org/0009-0008-6968-8858, Hossam, Mai, Król-Józaga, Bartłomiej ORCID: https://orcid.org/0000-0003-2526-0629, Jasiński, Maciej ORCID: https://orcid.org/0000-0001-6467-2752, Pienkowski, Victor Murcia ORCID: https://orcid.org/0000-0002-1383-8019, Sanecka-Duin, Anna ORCID: https://orcid.org/0000-0001-7684-2149, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Haji, Mohamed, Szatanek, Rafał, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Kaczmarczyk, Jan ORCID: https://orcid.org/0000-0002-1629-3675, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Blum, Agnieszka and Klatt, Martin G. ORCID: https://orcid.org/0000-0001-8703-7305
Molecular & Cellular Proteomics 25
(5): 101560.
May 2026
Accelerating Leigh syndrome drug discovery through deep learning screening in brain organoids.
Menacho, Carmen ORCID: https://orcid.org/0000-0001-9754-6322, Okawa, Satoshi, Álvarez-Merz, Iris ORCID: https://orcid.org/0000-0002-2585-1093, Wittich, Annika, Muñoz-Oreja, Mikel, Lisowski, Pawel ORCID: https://orcid.org/0000-0002-3634-1072, Martín, Mario López, Pentimalli, Tancredi Massimo ORCID: https://orcid.org/0000-0002-8461-7918, Zakin, Shiri, Thevandavakkam, Mathuravani, Jerred, Caleb, Lickfett, Selene ORCID: https://orcid.org/0000-0002-3726-9551, Petersilie, Laura, Rybak-Wolf, Agnieszka ORCID: https://orcid.org/0000-0002-1192-5290, Seibt, Annette, Herebian, Diran, Inak, Gizem, Brodesser, Susanne ORCID: https://orcid.org/0000-0001-5631-0663, Zaliani, Andrea ORCID: https://orcid.org/0000-0002-1740-8390, Mlody, Barbara ORCID: https://orcid.org/0000-0001-5184-1772, Donnelly, Justin, Woleben, Kasey, Soriano, Francesc Xavier ORCID: https://orcid.org/0000-0003-1678-7162, Fernandez-Checa, Jose C., Ventura, Natascia ORCID: https://orcid.org/0000-0001-8718-4321, Cambridge, Sidney, Mayatepek, Ertan ORCID: https://orcid.org/0000-0001-8460-3738, Spinazzola, Antonella ORCID: https://orcid.org/0000-0003-4242-8091, Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Rossi, Andrea ORCID: https://orcid.org/0000-0001-5863-6448, Peralvarez-Marin, Alex ORCID: https://orcid.org/0000-0002-3457-0875, Distelmaier, Felix ORCID: https://orcid.org/0000-0003-4304-7848, Perlstein, Ethan, Holt, Ian J., Puighermanal, Emma ORCID: https://orcid.org/0000-0003-4271-9104, Pless, Ole ORCID: https://orcid.org/0000-0002-1468-316X, Rose, Christine R. ORCID: https://orcid.org/0000-0002-9684-3592, Del Sol, Antonio ORCID: https://orcid.org/0000-0002-9926-617X and Prigione, Alessandro ORCID: https://orcid.org/0000-0001-9457-1952
Nature Communications 17
(1): 3570.
20 April 2026
Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts.
Merkt, Wolfgang ORCID: https://orcid.org/0000-0002-3108-154X, Rodon, Lea ORCID: https://orcid.org/0009-0004-7774-9690, Deicher, Franca S. ORCID: https://orcid.org/0009-0009-9624-1653, Freitag, Merle, Claus, Maren ORCID: https://orcid.org/0000-0001-8732-0645, Lister, Rachael, Han, Hongwei ORCID: https://orcid.org/0000-0002-0190-4461, Zhou, Yan ORCID: https://orcid.org/0000-0002-8822-5276, Horne, Arik ORCID: https://orcid.org/0000-0002-4209-4573, Stütz, Ayla ORCID: https://orcid.org/0009-0004-9123-4044, Li, Yi-Nan ORCID: https://orcid.org/0000-0001-8934-9361, Kreuter, Michael, Kahn, Nicolas ORCID: https://orcid.org/0000-0002-5403-8069, Schneider, Marc A. ORCID: https://orcid.org/0000-0001-8269-3821, Egea-Zorrilla, Alejandro ORCID: https://orcid.org/0000-0002-5522-8227, Blasco-Iturri, Zuriñe, Nikulina, Nadezhda ORCID: https://orcid.org/0009-0001-2533-0984, Turkowski, Kati ORCID: https://orcid.org/0000-0002-8455-8268, Ruppert, Clemens ORCID: https://orcid.org/0000-0002-0938-2469, Guenther, Andreas ORCID: https://orcid.org/0000-0002-2187-0975, Rizzo, Roberta ORCID: https://orcid.org/0000-0001-9507-9126, Rizzo, Sabrina, Ferraresi, Matteo, Hübschmann, Daniel ORCID: https://orcid.org/0000-0002-6041-7049, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Blank, Norbert ORCID: https://orcid.org/0000-0002-9419-1690, Watzl, Carsten ORCID: https://orcid.org/0000-0001-5195-0995, Tykocinski, Lars-Oliver ORCID: https://orcid.org/0000-0002-7645-1559, Lorenz, Hanns-Martin ORCID: https://orcid.org/0000-0001-8197-8681, Savai, Rajkumar ORCID: https://orcid.org/0000-0003-1538-2091, Pardo-Saganta, Ana ORCID: https://orcid.org/0000-0002-5926-6255 and Lagares, David ORCID: https://orcid.org/0000-0002-7317-8796
Science Translational Medicine 18
(849): eadq5442.
May 2026
Outcomes of CAR-T cell therapy and bispecific antibodies as single-modality and sequential strategies in relapsed/refractory multiple myeloma.
Merz, Maximilian, Jelinek, Tomas, Pabst, Thomas, Teipel, Raphael, Albici, Anca-Maria, von Tresckow, Bastian, Teichert, Marcel, Demel, Uta Margareta ORCID: https://orcid.org/0000-0002-6480-4185, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Wesener, Marie Christine, Holderried, Tobias A.W., Schmitz, Friederike, Rößiger, Friedrich-Linus, Müller, Fabian, Hoffmann, Michele, Stölzel, Friedrich, Tovar, Natalia, Baermann, Ben-Niklas, Stork, Martin, Jungova, Alexandra, Minarik, Jiri, Radocha, Jakub, Spicka, Ivan, Pour, Ludek, Novak, Polona, Slajpah, Klara, Rener, Karla, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Bohl, Stephan, Fandrei, David, Born, Patrick, Vucinic, Vladan, Kröger, Nicolaus, Strassl, Irene, Schub, Natalie, Hájek, Roman, Sever, Matjaz, Fernández de Larrea, Carlos and Gagelmann, Nico
Blood Cancer Discovery 7
(5): 697-710.
3 September 2026
Spatialproteomics: an interoperable toolbox for analyzing highly multiplexed fluorescence image data.
Meyer-Bender, Matthias ORCID: https://orcid.org/0000-0002-0448-4546, Vöhringer, Harald ORCID: https://orcid.org/0000-0003-2513-4518, Schniederjohann, Christina ORCID: https://orcid.org/0009-0001-2693-8086, Koziel, Sarah ORCID: https://orcid.org/0009-0003-8002-5127, Chung, Erin, Popova, Ekaterina ORCID: https://orcid.org/0000-0003-2559-3685, Brobeil, Alexander, Griese, Nicklas ORCID: https://orcid.org/0009-0009-9461-4364, Kolks, Nora, Held, Lisa-Maria, Munir, Aamir, Dietrich, Sascha ORCID: https://orcid.org/0000-0002-0648-1832, Bruch, Peter-Martin ORCID: https://orcid.org/0000-0002-9992-3109 and Huber, Wolfgang ORCID: https://orcid.org/0000-0002-0474-2218
Nature Methods 23
(8): 1564-1573.
August 2026
Fractal dimension of high-risk neuroblastoma vascularity in MRI is associated with chemotherapy response and event-free survival.
Michallek, Florian, Dewey, Marc, Hero, Barbara, Hauptmann, Kathrin, Veldhoen, Simon, Paulsen, Verena, Astrahantseff, Kathy, Deubzer, Hedwig E. ORCID: https://orcid.org/0000-0002-6115-4893, Simon, Thorsten, Eggert, Angelika and Thole-Kliesch, Theresa M.
Radiology: Imaging Cancer 8
(1): e250070.
1 January 2026
RMSDistance: the release for the publication.
Mikirtumov, Vasilii ORCID: https://orcid.org/0009-0004-6849-4825 and Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274
[Dataset]
16 July 2026
In vivo RNA metabolic labeling identifies the sentinel cells of the regenerating zebrafish heart [bulk_slamseq].
Mintcheva, J. ORCID: https://orcid.org/0000-0003-0793-6277, Tseng, T., Goumenaki, P., Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Senoussi, A. ORCID: https://orcid.org/0000-0002-7066-8917, Schäfer, R., Lelek, S., Panakova, D. ORCID: https://orcid.org/0000-0002-8739-6225, Stainier, D. and Junker, J. ORCID: https://orcid.org/0000-0002-2826-8290
[Dataset]
30 March 2026
In vivo RNA metabolic labeling identifies the sentinel cells of the regenerating zebrafish heart [scrna-seq].
Mintcheva, J. ORCID: https://orcid.org/0000-0003-0793-6277, Tseng, T., Goumenaki, P., Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Senoussi, A. ORCID: https://orcid.org/0000-0002-7066-8917, Schäfer, R., Lelek, S., Panakova, D. ORCID: https://orcid.org/0000-0002-8739-6225, Stainier, D. and Junker, J. ORCID: https://orcid.org/0000-0002-2826-8290
[Dataset]
30 March 2026
In vivo RNA metabolic labeling identifies the sentinel cells of the regenerating zebrafish heart [scslam-seq].
Mintcheva, J. ORCID: https://orcid.org/0000-0003-0793-6277, Tseng, T., Goumenaki, P., Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Senoussi, A. ORCID: https://orcid.org/0000-0002-7066-8917, Schäfer, R., Lelek, S., Panakova, D. ORCID: https://orcid.org/0000-0002-8739-6225, Stainier, D. and Junker, J. ORCID: https://orcid.org/0000-0002-2826-8290
[Dataset]
30 March 2026
In vivo single-cell RNA metabolic labeling resolves early transcriptional responders in the regenerating zebrafish heart.
Mintcheva, Janita ORCID: https://orcid.org/0000-0003-0793-6277, Tseng, Tzu-Lun ORCID: https://orcid.org/0000-0003-1319-0141, Goumenaki, Pinelopi, Neuschulz, Anika ORCID: https://orcid.org/0000-0001-6163-3344, Senoussi, Anis ORCID: https://orcid.org/0000-0002-7066-8917, Lelek, Sara, Lim, Khai Lone ORCID: https://orcid.org/0000-0003-0295-330X, Ming, Zhitao, Schäfer, Ronny, Hnatiuk, Alisa, Ninov, Nikolay ORCID: https://orcid.org/0000-0003-3286-6100, Beisaw, Arica ORCID: https://orcid.org/0000-0002-6658-6978, McGrail, Maura ORCID: https://orcid.org/0000-0001-9308-6189, Ben Lai, Shih-Lei ORCID: https://orcid.org/0000-0002-1409-4701, Panáková, Daniela ORCID: https://orcid.org/0000-0002-8739-6225, Stainier, Didier Y. R. ORCID: https://orcid.org/0000-0002-0382-0026 and Junker, Jan Philipp ORCID: https://orcid.org/0000-0002-2826-8290
Nature Communications 17
(1): 4073.
5 May 2026
Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs.
Mota-Gómez, Irene ORCID: https://orcid.org/0000-0001-8308-8017, Rodríguez, Juan Antonio, Dupont, Shannon, Hurtado, Alicia ORCID: https://orcid.org/0000-0001-6267-704X, Cadenas, Vanessa, Zuber, Leo, Maceda, Iago, Lao, Oscar, Jedamzick, Johanna, Kühn, Ralf ORCID: https://orcid.org/0000-0003-1694-9803, Lacadie, Scott ORCID: https://orcid.org/0000-0002-0893-5340, García-Moreno, Sara Alexander, Torres, Miguel, Real, Francisca M. ORCID: https://orcid.org/0000-0003-0692-2260, Acemel, Rafael D., Capel, Blanche, Marti-Renom, Marc A. and Lupíañez, Dario G. ORCID: https://orcid.org/0000-0002-3165-036X
Nature Structural & Molecular Biology 33
(4): 577-589.
April 2026
SUMOylation of HSF1 orchestrates transcriptional and splicing programs during the proteotoxic stress response.
Mueller, Stefan ORCID: https://orcid.org/0000-0002-8792-7700, Patra, Upayan, Kuska, Svenja, Mosler, Thorsten ORCID: https://orcid.org/0000-0003-1800-2680, Makarov, Timur, Mukhopadhyay, Urbi, Münch, Christian ORCID: https://orcid.org/0000-0003-3832-090X, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Müller-McNicoll, Michaela ORCID: https://orcid.org/0000-0002-7174-8310 and Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872
Research Square
: rs.3.rs-10283915/v1.
16 July 2026
The protein phosphatase inhibitor LB100 targets the mesenchymal lineage of pancreatic ductal adenocarcinoma.
Murr, Janine, Schneider, Carolin, Duan, Ningjun, Köse, Hazal, Rajamani, Anantharamanan, He, Xueyang, Buchloh, Jonas, Hintze, Christian, Naik, Atharva, Goeke, Daniel, Rjasanow, Nicole, Krauß, Lukas, Nguyen, Alexandra, Widholz, Sebastian A., Schneeweis, Christian, Trozzo, Riccardo, Orben, Felix, Mueller, Sebastian, Öllinger, Rupert, Montero, Juan J., Dudek, Michael, Knolle, Percy, Kong, Bo, Ellenrieder, Volker, Contreras, Constanza Tapia, Hessmann, Elisabeth, Grade, Marian, Ghadimi, Michael, Braun, Christian J., Rad, Roland, Reichert, Maximillian, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Schmid, Roland M., Boutz, Paul L., Saur, Dieter, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Krämer, Oliver H. and Schneider, Günter ORCID: https://orcid.org/0000-0003-1840-4508
MedComm 7
(6): e70794.
June 2026
Integrative structural interactomics reveals protein organization and structure in a giant virus.
Mühlberg, Lars ORCID: https://orcid.org/0009-0008-8046-007X, Ruta, Julia ORCID: https://orcid.org/0009-0007-0524-6885, Mikirtumov, Vasilii ORCID: https://orcid.org/0009-0004-6849-4825, Burton-Smith, Raymond ORCID: https://orcid.org/0000-0002-1535-6419, Murata, Kazuyoshi ORCID: https://orcid.org/0000-0001-9446-3652, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274, Okamoto, Kenta ORCID: https://orcid.org/0000-0002-4858-1196, Bogdanow, Boris ORCID: https://orcid.org/0000-0002-9634-7353 and Liu, Fan ORCID: https://orcid.org/0000-0002-2358-549X
Nature Communications 17
(1): 6139.
13 July 2026
Large-scale endoplasmic reticulum membrane solidification spatially organises proteins under thermal or metabolic stress.
Müller, Paul M. ORCID: https://orcid.org/0000-0001-9056-4114, Mikolaj, Melissa R., Belbaraka, Elmehdi, Hartstein, Finn, Altinoluk, Sophia, Perder, Björn, Trnka, Philipp, Welke, Robert-William, Naumann, Heike ORCID: https://orcid.org/0000-0003-3883-0432, Taudien, Nina, Kunz, Severine ORCID: https://orcid.org/0000-0002-0131-3506, Solimena, Michele ORCID: https://orcid.org/0000-0002-3653-8107, Levental, Ilya ORCID: https://orcid.org/0000-0002-1206-9545, Levental, Kandice R., Müller, Andreas ORCID: https://orcid.org/0000-0002-3560-5769, Ewers, Helge ORCID: https://orcid.org/0000-0003-3948-4332, Narayan, Kedar and Rocks, Oliver ORCID: https://orcid.org/0000-0001-6349-9193
bioRxiv
: 2026.04.09.717431.
12 April 2026
Integrative modelling reveals the structure of the human Mic60-Mic19 subcomplex and its role as a diffusion barrier in mitochondria.
Nathanail, Evangelia ORCID: https://orcid.org/0009-0004-9579-8074, Rolando, Edoardo ORCID: https://orcid.org/0009-0001-8276-1406, Ruwolt, Max ORCID: https://orcid.org/0009-0000-7220-406X, Zaporozhets, Iryna, Liu, Fan ORCID: https://orcid.org/0000-0002-2358-549X, Clementi, Cecilia ORCID: https://orcid.org/0000-0001-9221-2358 and Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414
bioRxiv
: 2026.01.30.702776.
30 January 2026
Structuring of the yeast endolysosomal pathway by the Rab5 guanine nucleotide exchange factors Muk1 and Vps9.
Nesterova, Alexandra, Prosser, Derek C. ORCID: https://orcid.org/0000-0002-6738-2758, Welke, Robert-William, Esch, Bianca M., Fröhlich, Florian ORCID: https://orcid.org/0000-0001-8307-2189, Sommer, Thomas ORCID: https://orcid.org/0000-0001-9990-5202, Langemeyer, Lars and Ungermann, Christian ORCID: https://orcid.org/0000-0003-4331-8695
Molecular Biology of the Cell 37
(3): ar23.
1 March 2026
OpenDVP: an experimental and computational framework for community-empowered deep visual proteomics.
Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799, Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Valdes, Daniela S. ORCID: https://orcid.org/0000-0002-1309-5147, Trinh, Minh Tien ORCID: https://orcid.org/0009-0000-2727-8449, Pentimalli, Tancredi ORCID: https://orcid.org/0000-0002-8461-7918, Klingeberg, Melissa ORCID: https://orcid.org/0009-0002-4778-2874, Schallenberg, Simon ORCID: https://orcid.org/0000-0002-7897-7116, Klauschen, Frederick ORCID: https://orcid.org/0000-0002-9131-2389, Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134, Florian, Stefan ORCID: https://orcid.org/0000-0002-0193-1320, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
bioRxiv
: 2025.07.13.662099v2.
15 January 2026
The cortical microenvironment drives early immune organization and controls early osteoclastogenesis in bone healing.
Noom, Anne ORCID: https://orcid.org/0009-0006-8589-5350, Oktay, Hülya Zeynep, Morgan, Duncan M. ORCID: https://orcid.org/0000-0002-3253-1362, Kroh, Sandy, Kasapi, Ana, Ellinghaus, Agnes, Kochan, Merle, Bolaji, Olufemi, Uecker, Ralf, Günther, Robert, Bianchi, M. Paula, Bucher, Christian H., Hildebrandt, Alexander ORCID: https://orcid.org/0000-0003-3560-1642, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Schmidt-Bleek, Katharina ORCID: https://orcid.org/0000-0002-5719-0867, Triantafyllopoulou, Antigoni, Hauser, Anja E. ORCID: https://orcid.org/0000-0002-7725-9526, Sawitzki, Birgit ORCID: https://orcid.org/0000-0001-8166-8579 and Duda, Georg N. ORCID: https://orcid.org/0000-0001-7605-3908
Nature Communications 17
(1): 9154.
27 August 2026
Molecular evolution of animal aging.
Nussey, Daniel H., d'Adda di Fagagna, Fabrizio, Bardin, Allison J. ORCID: https://orcid.org/0000-0002-0200-4465, Blau, Helen, Brunet, Anne, Bulavin, Dmitry V., Guo, Longhua, Hara, Eiji ORCID: https://orcid.org/0000-0001-7821-3960, Junker, Jan Philipp ORCID: https://orcid.org/0000-0002-2826-8290, Gorbunova, Vera ORCID: https://orcid.org/0000-0001-8979-0333, Mittelbrunn, Maria ORCID: https://orcid.org/0000-0003-3487-8762, Rera, Michael ORCID: https://orcid.org/0000-0002-6574-6511, Reznick, Jane, Seluanov, Andrei ORCID: https://orcid.org/0000-0003-3400-538X, Schumacher, Björn ORCID: https://orcid.org/0000-0001-6097-5238, Teeling, Emma C., Valenzano, Dario Riccardo ORCID: https://orcid.org/0000-0002-8761-8289, Ye, Jing, Yun, Maximina H. ORCID: https://orcid.org/0000-0001-9019-2453, Garinis, George A. ORCID: https://orcid.org/0000-0002-3200-5004 and Gilson, Eric ORCID: https://orcid.org/0000-0001-5738-6723
EMBO Journal 45
(7): 2095-2111.
1 April 2026
Population-scale sequencing resolves determinants of persistent EBV DNA.
Nyeo, Sherry S., Cumming, Erin M., Burren, Oliver S., Pagadala, Meghana S., Gutierrez, Jacob C., Ali, Thahmina A., Kida, Laura C., Chen, Yifan, Chu, Hoyin, Hu, Fengyuan, Zou, Xueqing Zoe, Hollis, Benjamin, Fabre, Margarete A., MacArthur, Stewart, Wang, Quanli, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Dey, Kushal K., Petrovski, Slavé, Dhindsa, Ryan S. and Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807
Nature 650
(8102): 664-672.
19 February 2026
Tau spreading coordinates intercellular lipid flux enhancing neuronal resilience to lipid toxicity.
Oliveras Martinez, Anna ORCID: https://orcid.org/0000-0002-5880-5245, Ibatici, Davide ORCID: https://orcid.org/0009-0007-8452-0335, Calvo Noriega, Maria ORCID: https://orcid.org/0000-0002-1097-2618, Mastrobuoni, Guido ORCID: https://orcid.org/0000-0003-4509-1295, Forbes, Martin ORCID: https://orcid.org/0000-0001-7775-8352, Santiago Padilla, Leandro Manuel ORCID: https://orcid.org/0000-0002-0873-7205, Aykul, Melisa ORCID: https://orcid.org/0009-0000-3837-9771, Horvatovic, Kamelija ORCID: https://orcid.org/0000-0002-3424-1326, Rusu, Mara-Camelia ORCID: https://orcid.org/0000-0002-8369-3580, Patsonis, Melina ORCID: https://orcid.org/0009-0000-6287-772X, Jutras-Dube, Laurent ORCID: https://orcid.org/0000-0003-4323-2840, Rossius, Jana ORCID: https://orcid.org/0009-0000-6011-9714, Cerda-Jara, Cledi Alicia ORCID: https://orcid.org/0000-0003-1783-5533, Bahry, Ella ORCID: https://orcid.org/0000-0002-6358-2576, Broichhagen, Johannes ORCID: https://orcid.org/0000-0003-3084-6595, Schmidt, Deborah ORCID: https://orcid.org/0000-0002-8621-9438, Metzger, Jakob ORCID: https://orcid.org/0000-0001-6813-4425, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Kunz, Severine ORCID: https://orcid.org/0000-0002-0131-3506, Rybak-Wolf, Agnieszka ORCID: https://orcid.org/0000-0002-1192-5290, Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299 and Birol, Melissa ORCID: https://orcid.org/0000-0003-3397-8446
bioRxiv
: 2026.07.30.741734.
4 August 2026
Liver-X-receptor agonism enhances T cell priming and activation to promote anti-tumor immunity.
Ostendorf, Benjamin N. ORCID: https://orcid.org/0000-0003-4492-9252, Goldstein, Jonathan G. ORCID: https://orcid.org/0009-0007-0679-1199, Liu, Shuang ORCID: https://orcid.org/0000-0003-2347-413X, Gonsalves, Foster C. ORCID: https://orcid.org/0009-0008-2330-3879, Bilanovic, Jana ORCID: https://orcid.org/0000-0002-0143-9694, Yuan, Mathias ORCID: https://orcid.org/0009-0002-9791-9795, Kim, Ji-Young ORCID: https://orcid.org/0000-0002-0775-8565, Rouya, Christopher ORCID: https://orcid.org/0000-0001-7746-5883, Tavazoie, Masoud ORCID: https://orcid.org/0000-0002-5013-0466 and Tavazoie, Sohail F. ORCID: https://orcid.org/0000-0002-4966-9018
Journal of Experimental Medicine 223
(4): e20252290.
6 April 2026
Exposure to a high-fat diet compromises gut health, behavior, and HPA axis function, with partial reversal when limited to adolescence.
Ott, Alexandra ORCID: https://orcid.org/0009-0000-4444-1834, Gül, Asude Zülal, Löber, Ulrike ORCID: https://orcid.org/0000-0001-7468-9531, Birkner, Till ORCID: https://orcid.org/0000-0003-2656-2821, Popova, Elena ORCID: https://orcid.org/0000-0002-3043-9650, Winter, Christine and Hadar, Ravit
Brain Research Bulletin 239
: 111883.
1 June 2026
Splicing dependency between EIF4G2 introns is mediated by exon definition and relies on a downstream splicing event.
P., Marie-Lee, V., Joëlle, M., Téa, S., Camille, T., Volodymyr ORCID: https://orcid.org/0009-0002-4141-6291, S., Egor ORCID: https://orcid.org/0009-0007-5306-076X, S., Ibrahim, M., Irmtraud M. ORCID: https://orcid.org/0000-0002-4048-3479 and Choquet, Karine
[Dataset]
30 June 2026
10X FFPE snRNASeq single Glia transcriptomes from IBD patients and controls.
Patankar, Jay V. ORCID: https://orcid.org/0000-0002-1884-7424, Penkert, Klara ORCID: https://orcid.org/0000-0002-9948-533X, Romagnani, Chiara ORCID: https://orcid.org/0000-0002-5167-7463 and Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164
[Dataset]
20 February 2026
Splicing dependency between EIF4G2 introns is mediated by exon definition and relies on a downstream splicing event.
Pelletier, Marie-Lee ORCID: https://orcid.org/0009-0001-5008-7533, Vincent, Joëlle, Malo, Téa, Séguin, Camille, Tsybulskyi, Volodymyr ORCID: https://orcid.org/0009-0002-4141-6291, Semenchenko, Egor ORCID: https://orcid.org/0009-0007-5306-076X, Adamou, Ibrahim Soumana ORCID: https://orcid.org/0000-0003-1634-0125, Meyer, Irmtraud M. ORCID: https://orcid.org/0000-0002-4048-3479 and Choquet, Karine
Journal of Biological Chemistry 302
(8): 113304.
August 2026
Suppl. Table 1 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 10 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 2 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 3 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 4 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 5 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 6 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 7 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 8 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Suppl. Table 9 from Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations.
Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, Nicoletta, Maurer, Katie, Kwok, Marwan, Lyu, Haoxiang, Lu, Wesley S., Oliveira, Giacomo, Gohil, Satyen H., Leshchiner, Ignaty, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, Donna S., Kim, Haesook T., Li, Shuqiang, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, Jerome, Getz, Gad, Garcia, Jacqueline S., Soiffer, Robert J., Livak, Kenneth J. and Wu, Catherine J.
[Dataset]
17 June 2026
(Submitted)
Teclistamab-induced rapid remission in refractory anti-Jo-1 antisynthetase syndrome.
Phithak, Elpida, Albach, Fredrik N., Minopoulou, Ioanna, Biesen, Robert, Kleyer, Arnd, Wiebe, Edgar, Siegert, Elise, Scholz, Veronika, Rehm, Marie, Cheng, Qingyu, Sattler, Arne, Bianco, Stefano, Fleischmann, Anja, Hermann, Kay-Geert, Walter-Rittel, Thula, Wagner, Moritz, Zernicke, Jan, Casteleyn, Vincent, Nielsen, Martin, Rose, Thomas, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Hütter-Krönke, Marie Luise, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Schneider, Udo, Kawelke, Leona, Ruffer, Nikolas, Stenzel, Werner, Krönke, Gerhard, Simon, David ORCID: https://orcid.org/0000-0001-8310-7820 and Alexander, Tobias
Annals of the Rheumatic Diseases 85
(1): 212-215.
January 2026
Blinatumomab in refractory SLE-associated immune thrombocytopenia.
Phithak, Elpida, Biesen, Robert, Albach, Fredrik N., Boeckel, Victoria, Minopoulou, Ioanna, Wiebe, Edgar, Cheng, Qingyu, Sattle, Arne, Rehm, Marie, Sinzinger, Benedikt, Beenken, Anne E., Staeck, Anja, Kleyer, Arnd, Hütter-Krönke, Marie Luise, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Krönke, Gerhard, Simon, David and Alexander, Tobias ORCID: https://orcid.org/0000-0003-1193-0097
Annals of the Rheumatic Diseases
1 September 2026
(In Press)
Prognostic impact of TROP2 in adenocarcinoma of the esophageal junction and stomach.
Pittrof, Anselm ORCID: https://orcid.org/0009-0006-2184-5282, Arnold, Alexander, Daum, Severin, Staudacher, Jonas, Berg, Erika, Hummel, Michael, Horst, David, Rau, Beate, Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X, Eich, Lisa Marie and Treese, Christoph ORCID: https://orcid.org/0000-0001-9120-6773
Clinical and Translational Oncology 28
(7): 2959-2966.
July 2026
IBDome: an integrated molecular, histopathological, and clinical atlas of inflammatory bowel diseases.
Plattner, Christina, Sturm, Gregor, Kühl, Anja A., Atreya, Raja, Carollo, Sandro, Rieder, Dietmar, Gronauer, Raphael, Günther, Michael, Ormanns, Steffen, Manzl, Claudia, Wirtz, Stefan, Meneghetti, Asier Rabasco, Hegazy, Ahmed N., Patankar, Jay V., Carrero, Zunamys I., Grabherr, Felix, Meyer, Moritz, Adolph, Timon E., Tilg, Herbert, Neurath, Markus F., Kather, Jakob Nikolas, Becker, Christoph, Siegmund, Britta and Trajanoski, Zlatko
Gastroenterology
10 June 2026
(In Press)
Additional file 1 of circVDJ-seq for T cell clonotype detection in single-cell and spatial multi-omics.
Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Raspe, Raphael, Pascual-Reguant, Anna, Theurillat, Ilan ORCID: https://orcid.org/0000-0002-1125-1951, Pentimalli, Tancredi Massimo ORCID: https://orcid.org/0000-0002-8461-7918, Hsieh, Yu-Hsin ORCID: https://orcid.org/0000-0003-3037-8728, Gil, Marine ORCID: https://orcid.org/0000-0002-3885-7806, Dietrich, Carola, Seeger-Zografakis, Michaela, Quedenau, Claudia ORCID: https://orcid.org/0000-0002-6846-4915, Wilde, Jeannine, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Fischer, Cornelius ORCID: https://orcid.org/0000-0003-0329-2435, Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891, Seitz, Volkhard, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Eggert, Angelika, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Borodina, Tatiana ORCID: https://orcid.org/0000-0002-6978-016X, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Altmueller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Hauser, Anja Erika and Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295
[Dataset]
12 June 2026
circVDJ-seq for T cell clonotype detection in single-cell and spatial multi-omics.
Plumbom, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Raspe, Raphael, Pascual-Reguant, Anna, Theurillat, Ilan ORCID: https://orcid.org/0000-0002-1125-1951, Pentimalli, Tancredi Massimo ORCID: https://orcid.org/0000-0002-8461-7918, Hsieh, Yu-Hsin ORCID: https://orcid.org/0000-0003-3037-8728, Gil, Marine ORCID: https://orcid.org/0000-0002-3885-7806, Dietrich, Carola, Seeger-Zografakis, Michaela, Quedenau, Claudia ORCID: https://orcid.org/0000-0002-6846-4915, Wilde, Jeannine, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Fischer, Cornelius ORCID: https://orcid.org/0000-0003-0329-2435, Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891, Seitz, Volkhard, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Eggert, Angelika, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Borodina, Tatiana ORCID: https://orcid.org/0000-0002-6978-016X, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Altmueller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Hauser, Anja Erika and Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295
Genome Medicine 18
(1): 84.
11 June 2026
Entinostat enhances antigen-specific CD8 T-cell response to immunotherapies in lung cancer models.
Porush, Esti, Arnon, Johnathan ORCID: https://orcid.org/0000-0002-5688-5712, Pinchover, Baruch, Stern, Esther, Shapira, Oz M., Jean, Didier, Blum, Galia, Yakobovich, Evalyn, Wald, Hanna, Peled, Amnon, Wang, Zhangmang, Belbaraka, Elmehdi, Friese, Christian, Blankenstein, Thomas ORCID: https://orcid.org/0000-0002-3357-4321, Kammertoens, Thomas ORCID: https://orcid.org/0000-0003-3309-5141 and Wald, Ori
Pharmaceuticals 19
(7): 1034.
July 2026
Accurate prediction of ecDNA in interphase cancer cells using deep neural networks.
Prasad, Gino, Rajkumar, Utkrisht, Curtis, Ellis J., Wong, Ivy Tsz-Lo, Yan, Xiaowei, Zhang, Shu, Brückner, Lotte ORCID: https://orcid.org/0000-0002-6155-2277, Turner, Kristen, Wiese, Julie, Wahl, Justin, Hemmati, Homa, Wu, Sihan, Theissen, Jessica, Fischer, Matthias, Chang, Howard Y., Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Mischel, Paul S. and Bafna, Vineet
Communications Biology 9
(1): 805.
15 June 2026
Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome.
Proce, Rosalba Olga, Steinecker, Maria, Giacomelli, Chiara ORCID: https://orcid.org/0000-0003-1466-1371, Uddström, Erika ORCID: https://orcid.org/0009-0009-5298-480X, Chatterjee, Anirban ORCID: https://orcid.org/0009-0002-8271-384X, Wüsthoff, Souhaila ORCID: https://orcid.org/0000-0001-7653-3565, Teixeira Alves, Luiz Gustavo ORCID: https://orcid.org/0000-0002-5822-4168, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Pohl, Tobias ORCID: https://orcid.org/0000-0001-8698-8475, Maxwell, Katie, Hortmann, Lucie, Kunz, Severine ORCID: https://orcid.org/0000-0002-0131-3506, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Bunina, Daria ORCID: https://orcid.org/0000-0002-5885-7440 and Hörnberg, Hanna ORCID: https://orcid.org/0000-0001-9142-1932
Molecular Psychiatry 31
(6): 3446-3461.
June 2026
Constitutive DUSP2 expression enhances lymphoid cell proliferation by activating CDK1 and promotes lymphomagenesis.
Qian, Yu, Panaampon, Jutatip, Chapuy, Bjoern, Zhang, Xueyan, Zhao, Xiujuan, Wang, Zhe, Zhang, Pengfei, Payungwong, Tongchai, Zhang, Aretina, Ke, Qiang, Zhong, Jing, Yuan, Ping, Zhang, Lei, Hong, Min, Choi, Il-Kyu, Guan, Jiankun, Calado, Dinis Pedro ORCID: https://orcid.org/0000-0001-8239-7184, Rodig, Scott, Pozdnyakova, Olga, Rajewsky, Klaus ORCID: https://orcid.org/0000-0002-6633-6370, Godinho, Susana A., Jirawatnotai, Siwanon, Wu, Hao, Shipp, Margaret A., Dougan, Stephanie K. and Zhang, Baochun
Cell Reports 45
(7): 117652.
28 July 2026
Unravelling drug resistant proteotypes through phenotype-resolved proteomics of single-cell derived colonies.
Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Das, Ridhima ORCID: https://orcid.org/0009-0007-0238-5935, Schallenberg, Simon ORCID: https://orcid.org/0000-0002-7897-7116, Riecken, Kristoffer ORCID: https://orcid.org/0000-0001-9050-6766, Tinhofer, Ingeborg ORCID: https://orcid.org/0000-0002-0512-549X and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
bioRxiv
: 2025.10.11.681009v3.
3 September 2026
Growing up as an immunologist among molecular geneticists.
Rajewsky, Klaus ORCID: https://orcid.org/0000-0002-6633-6370
European Journal of Immunology 56
(8): e70256.
August 2026
Additional file 2 of Single-cell epigenetic and transcriptomic states across the continuum of monoclonal B cell lymphocytosis to chronic lymphocytic leukemia.
Rathgeber, Anja C. ORCID: https://orcid.org/0000-0003-3264-1040, Fernandes, Stacey M., Nagler, Adi, Li, Shuqiang, Dorfman, David M., Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Davids, Matthew S., Brown, Jennifer R., Livak, Kenneth J., Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Wu, Catherine J. and Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207
[Dataset]
22 May 2026
Single-cell epigenetic and transcriptomic states across the continuum of monoclonal B cell lymphocytosis to chronic lymphocytic leukemia.
Rathgeber, Anja C. ORCID: https://orcid.org/0000-0003-3264-1040, Fernandes, Stacey M., Nagler, Adi, Li, Shuqiang, Dorfman, David M., Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Davids, Matthew S., Brown, Jennifer R., Livak, Kenneth J., Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Wu, Catherine J. and Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207
Genome Biology 27
(1): 175.
21 May 2026
Shortcomings of silhouette in single-cell integration benchmarking.
Rautenstrauch, Pia ORCID: https://orcid.org/0000-0002-0070-4759 and Ohler, Uwe ORCID: https://orcid.org/0000-0002-0881-3116
Nature Biotechnology 44
(6): 954-958.
June 2026
Microbial spectrum and antimicrobial resistance are associated with outcomes after endoscopic ultrasound-guided therapy of pancreatic fluid collections.
Razpotnik, Marcel, Jürgensen, Christian, Sigal, Michael ORCID: https://orcid.org/0000-0003-4772-0761, Herta, Toni, Çelebi, Özlem, Adler, Andreas, Leonhardt, Silke, Branchi, Federica, Buchkremer, Juliane, Kouladouros, Konstantinos, Wree, Alexander, Pilz, Jürgen, Heimesaat, Markus M, Siegmund, Britta, Engelmann, Cornelius and Tacke, Frank
Scientific Reports 16
(1): 24152.
5 August 2026
A CD22-specific T-cell receptor enables effective adoptive T-cell therapy for B-cell malignancies.
Rhein, Simone ORCID: https://orcid.org/0000-0002-9445-2352, Çakmak-Görür, Neşe ORCID: https://orcid.org/0000-0001-7857-2461, Grunert, Corinna ORCID: https://orcid.org/0000-0001-8376-8629, Al-Tabatabaee, Sarah Hayder Jalal, Serin, Nazli, Leisegang, Matthias ORCID: https://orcid.org/0000-0003-3692-7142, Timiliotis, Stefanos, Ohlmeier, Luisa Sophie ORCID: https://orcid.org/0000-0002-3381-3003, Freund, Cäcilia ORCID: https://orcid.org/0000-0002-9260-0032, Willimsky, Gerald ORCID: https://orcid.org/0000-0002-9693-948X, Konietschke, Frank, Kieback, Elisa ORCID: https://orcid.org/0000-0003-3831-2846, Tasian, Sarah K., Chapuy, Bjoern, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Blankenstein, Thomas ORCID: https://orcid.org/0000-0002-3357-4321, Pezzutto, Antonio ORCID: https://orcid.org/0000-0002-3246-4470 and Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947
Blood 147
(10): 1058-1069.
5 March 2026
From suspected lymphoma to self-limiting lymphadenitis: Kikuchi-Fujimoto disease in focus.
Rieck, Julian, Dittmayer, Carsten, Janz, Martin ORCID: https://orcid.org/0000-0002-1127-0044, Horst, David and Schallenberg, Simon
Journal of Hematopathology 19
(1): 30.
3 June 2026
Comprehensive molecular analyses for diagnosis and treatment guidance in an adult neuroblastoma patient.
Rieke, Damian T. ORCID: https://orcid.org/0000-0003-0027-7977, Schwartz, Stefan, Ochsenreither, Sebastian, Chapuy, Björn, Amthauer, Holger, Deubzer, Hedwig E. ORCID: https://orcid.org/0000-0002-6115-4893, Lehmann, Annika, Keilholz, Ulrich, Wardelmann, Eva, Vokuhl, Christian, Eggert, Angelika, Fröhling, Stefan, Horst, David, Capper, David ORCID: https://orcid.org/0000-0003-1945-497X, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Dragomir, Mihnea P. and Schallenberg, Simon ORCID: https://orcid.org/0000-0002-7897-7116
Oncologist 31
(5): oyag132.
May 2026
Gonadal function and fertility after Hodgkin lymphoma treatment with nivolumab-AVD in the 2 GHSG NIVAHL trial.
Robertz, Anne Sophie, Bühnen, Ina, Meissner, Julia, Trautmann-Grill, Karolin, Herhaus, Peter, Halbsguth, Teresa, Schaub, Valdete, Kerkhoff, Andrea, Mathas, Stephan ORCID: https://orcid.org/0000-0001-9626-1413, Bormann, Matthias, Dickhut, Andreas ORCID: https://orcid.org/0009-0008-9794-9875, Jaworek, Christian P. ORCID: https://orcid.org/0009-0007-9338-2624, Fuchs, Michael, Kobe, Carsten ORCID: https://orcid.org/0000-0002-2909-0826, Baues, Christian ORCID: https://orcid.org/0000-0003-1733-6064, Borchmann, Peter, von Tresckow, Bastian ORCID: https://orcid.org/0000-0003-1410-4487, Behringer, Karolin ORCID: https://orcid.org/0000-0002-7035-1784 and Bröckelmann, Paul J. ORCID: https://orcid.org/0000-0001-9662-9900
Blood 147
(25): 3118-3121.
18 June 2026
A kinetics-based model of haematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells.
Rodríguez-Correa, Esther, Grünschläger, Florian ORCID: https://orcid.org/0000-0003-0021-6912, Nizharadze, Tamar, Anstee, Natasha, Al-Sabah, Jude, Kumpost, Vojtech, Sedlmeier, Anastasia ORCID: https://orcid.org/0009-0002-0418-2131, Li, Congxin, Ball, Melanie, Fotopoulou, Foteini, Jayarajan, Jeyan ORCID: https://orcid.org/0009-0009-6205-143X, Ghezzi, Ian, Knoch, Julia, Druce, Megan, Aurich, Kleo, Büchler-Schäff, Marleen, Lux, Susanne, Hernández-Malmierca, Pablo ORCID: https://orcid.org/0000-0003-4529-384X, Gräsel, Julius, Vonficht, Dominik ORCID: https://orcid.org/0000-0002-5579-7083, López-Osias, Marta, González-Saiz, Elvira ORCID: https://orcid.org/0000-0002-8455-1453, Fernández-Pérez, Daniel, Mathioudaki, Anna ORCID: https://orcid.org/0000-0003-4617-7015, Zaugg, Judith, Rodríguez-Fraticelli, Alejo ORCID: https://orcid.org/0000-0002-4017-8714, Mikut, Ralf, Trumpp, Andreas ORCID: https://orcid.org/0000-0002-6212-3466, Höfer, Thomas ORCID: https://orcid.org/0000-0003-3560-8780, Hübschmann, Daniel ORCID: https://orcid.org/0000-0002-6041-7049, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051 and Milsom, Michael D. ORCID: https://orcid.org/0000-0002-3567-254X
Nature Cell Biology 28
(6): 1127-1140.
June 2026
Data for manuscript: Integrative modelling reveals the structure of the human Mic60-Mic19 subcomplex and its role as a diffusion barrier in mitochondria.
Rolando, Edoardo ORCID: https://orcid.org/0009-0001-8276-1406, Nathanail, Evangelia ORCID: https://orcid.org/0009-0004-9579-8074, Clementi, Cecilia ORCID: https://orcid.org/0000-0001-9221-2358 and Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414
[Dataset]
10 August 2026
Towards crystal structures of filament forming proteins.
Roske, Yvette ORCID: https://orcid.org/0000-0001-6237-388X, Leidert, Martina, Rehbein, Kristina and Diehl, Anne ORCID: https://orcid.org/0000-0001-7295-9972
bioRxiv
: 2026.02.22.707290.
22 February 2026
Liquid biopsy-based detection of acquired MET resistance enables sequential targeted therapy in MET fusion-positive NSCLC.
Rosnev, Stanislav ORCID: https://orcid.org/0000-0003-0256-7038, Klein, Katharina, Heukamp, Lukas, Lenk, Julian, Joosten, Maria, Möbs, Markus ORCID: https://orcid.org/0000-0002-1502-3032, Grob, Tobias, Benary, Manuela ORCID: https://orcid.org/0000-0002-3067-2030, Vecchione, Loredana, Ott, Claus-Eric ORCID: https://orcid.org/0000-0003-3627-3791, Modest, Dominik P., Knödler, Maren, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Frost, Nikolaj ORCID: https://orcid.org/0000-0001-7452-7129, Keilholz, Ulrich, Kiewe, Philipp and Rieke, Damian T. ORCID: https://orcid.org/0000-0003-0027-7977
Oncologist 31
(6): oyag151.
June 2026
Genetic elements promote retention of extrachromosomal DNA in cancer cells.
Sankar, Venkat, Hung, King L., Gnanasekar, Aditi, Wong, Ivy Tsz-Lo ORCID: https://orcid.org/0000-0002-9761-3422, Shi, Quanming, Kraft, Katerina, Jones, Matthew G., He, Britney Jiayu, Yan, Xiaowei ORCID: https://orcid.org/0000-0002-4846-8812, Belk, Julia A. ORCID: https://orcid.org/0000-0003-4724-6158, Liu, Kevin J. ORCID: https://orcid.org/0000-0003-3836-3213, Agarwal, Sangya ORCID: https://orcid.org/0000-0003-4272-515X, Wang, Sean K. ORCID: https://orcid.org/0000-0003-1557-8510, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Mischel, Paul S. ORCID: https://orcid.org/0000-0002-4560-2211 and Chang, Howard Y. ORCID: https://orcid.org/0000-0002-9459-4393
Nature 649
(8095): 152-160.
1 January 2026
Yamadazyma mexicana isolate IT1 large subunit ribosomal RNA gene, partial sequence.
Santiago-Padilla, L.M. ORCID: https://orcid.org/0000-0002-0873-7205, Banos-Quintana, A.P. and Lehenberger, M.
[Dataset]
7 April 2026
(Submitted)
Trichoderma harzianum isolate P338 large subunit ribosomal RNA gene, partial sequence.
Santiago-Padilla, L.M. ORCID: https://orcid.org/0000-0002-0873-7205, Banos-Quintana, A.P. and Lehenberger, M.
[Dataset]
6 April 2026
Nanobodies specific for Vβ11 enable detection and noninvasive imaging of antigen-specific T cells in vivo.
Scharmann, Stephanie D. ORCID: https://orcid.org/0009-0003-5347-228X, Faber, Francisca, Hoorens van Heyningen, Lauren, Reljić, Mirna, Huisman, Brooke D., Faas, Priscilla P.M., Medhi, Himadri, Meyer, Manpreet ORCID: https://orcid.org/0009-0004-5700-8529, Gall, Camille Le, Sahay, Ishani, Suresh, Pavana, van Dalen, Floris J., Becht, Nanette, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Birnbaum, Michael E. ORCID: https://orcid.org/0000-0002-2281-3518, Ploegh, Hidde L. and Pishesha, Novalia ORCID: https://orcid.org/0000-0002-8124-1265
Journal of Immunology 215
(9): vkag237.
September 2026
Oncogene inactivation-induced senescence facilitates tumor relapse.
Schmitt, Philipp ORCID: https://orcid.org/0009-0008-1643-0079, Hönig, Katrin, Norcia, Maria Teresa ORCID: https://orcid.org/0009-0007-8042-4530, Nogueira, Marta F. ORCID: https://orcid.org/0000-0002-7607-4570, Flore, Viktoria ORCID: https://orcid.org/0009-0001-3023-433X, Simó Vesperinas, Inés ORCID: https://orcid.org/0000-0001-8965-127X, Villoro-Agud, Maria ORCID: https://orcid.org/0009-0005-5525-0589, Peng, Lushan, Safyürek, Zuhal ORCID: https://orcid.org/0009-0004-8412-5069, Tariq, Mehreen ORCID: https://orcid.org/0009-0003-5217-2226, Milojkovic, Ana ORCID: https://orcid.org/0009-0001-7621-2283, Anders, Kathleen ORCID: https://orcid.org/0000-0002-0429-200X, Schröck, Evelin ORCID: https://orcid.org/0000-0002-3377-1704, Sauer, Sascha ORCID: https://orcid.org/0000-0002-4794-3693, Uyar, Bora ORCID: https://orcid.org/0000-0002-3170-4890, Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117, Willimsky, Gerald ORCID: https://orcid.org/0000-0002-9693-948X, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Martínez-Reyes, Inmaculada ORCID: https://orcid.org/0000-0003-0479-1535 and Blankenstein, Thomas ORCID: https://orcid.org/0000-0002-3357-4321
Nature Communications 17
: 6244.
15 July 2026
Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models.
Schoof, Melanie ORCID: https://orcid.org/0000-0002-1373-8130, Zheng, Tuyu ORCID: https://orcid.org/0000-0003-3385-7353, Sill, Martin ORCID: https://orcid.org/0000-0001-7616-7665, Imle, Roland ORCID: https://orcid.org/0000-0001-9564-6952, Cais, Alessia, Altendorf, Lea, Fürst, Alicia, Hofmann, Nina, Ernst, Kati ORCID: https://orcid.org/0000-0002-8555-5907, Vonficht, Dominik ORCID: https://orcid.org/0000-0002-5579-7083, Chan, Kenneth Chun-Ho, Holland-Letz, Tim, Postlmayr, Andreas, Shiraishi, Ryo, Wang, Wanchen, Morcavallo, Alaide, Spohn, Michael ORCID: https://orcid.org/0000-0001-9160-4157, Göbel, Carolin ORCID: https://orcid.org/0000-0002-7345-2089, Niesen, Judith, Peter, Levke-Sophie ORCID: https://orcid.org/0009-0005-7283-9061, Bourdeaut, Franck ORCID: https://orcid.org/0000-0001-9489-6781, Han, Zhi-Yan, Pei, Yanxin, Murad, Najiba, Swartling, Fredrik J. ORCID: https://orcid.org/0000-0002-8460-4367, Taylor, Jessica ORCID: https://orcid.org/0000-0001-8565-8589, Yadav, Monika, Gibson, Garrett R., Gilbertson, Richard J. ORCID: https://orcid.org/0000-0001-7539-9472, Dottermusch, Matthias, Roy, Rajanya, Kerl, Kornelius ORCID: https://orcid.org/0000-0002-5676-8102, Glass, Rainer, Cheng, Jiying, Horstmann, Martin A., Wolters-Eisfeld, Gerrit ORCID: https://orcid.org/0000-0002-2984-6515, Zhao, Haotian ORCID: https://orcid.org/0000-0003-2315-8452, Sturm, Dominik, Yadav, Viveka Nand, Chesler, Louis ORCID: https://orcid.org/0000-0001-7842-2068, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Weiss, William A., Northcott, Paul A ORCID: https://orcid.org/0000-0002-1220-5252, Kutscher, Lena M. ORCID: https://orcid.org/0000-0002-1130-4582, Guerreiro Stucklin, Ana ORCID: https://orcid.org/0000-0003-3136-9241, Ayrault, Olivier ORCID: https://orcid.org/0000-0002-7942-6674, Neumann, Julia E. ORCID: https://orcid.org/0000-0002-1162-8771, Kawauchi, Daisuke, Jones, David T.W. ORCID: https://orcid.org/0000-0002-2036-5141, Pajtler, Kristian, Banito, Ana ORCID: https://orcid.org/0000-0003-2188-0003, Pfister, Stefan M. ORCID: https://orcid.org/0000-0002-5447-5322, Schüller, Ulrich ORCID: https://orcid.org/0000-0002-8731-1121 and Zuckermann, Marc ORCID: https://orcid.org/0000-0003-0148-3289
Nature Genetics 58
(1): 143-156.
January 2026
InteRRact: a web server for the interactive exploration and comparison of transcriptome-wide RNA-RNA interactions.
Semenchenko, Egor ORCID: https://orcid.org/0009-0007-5306-076X, Luo, Jingwen, Tsybulskyi, Volodymyr ORCID: https://orcid.org/0009-0002-4141-6291, Rettig, Charlie ORCID: https://orcid.org/0000-0003-2354-1056 and Meyer, Irmtraud M. ORCID: https://orcid.org/0000-0002-4048-3479
NAR Genomics and Bioinformatics 8
(3): lqag089.
September 2026
Osteopontin-driven TGF-β1 signaling via integrin αvβ3-NF-κB axis impairs NK cell function in head and neck squamous cell carcinoma.
Shen, Zhe, Li, Xin, Luo, Shi, Gao, Yuzhang, Safia, Imadoudini Hassimi, Jiang, Jie, Qi, Xin, Huang, Wei, Liu, Yalan, Fang, Xing, Tang, Yaoyun and Wu, Ping
Apoptosis 31
(6): 155.
June 2026
Teclistamab induces rapid clinical response and deep tissue depletion in refractory systemic sclerosis-a case series.
Siegert, Elise, Phithak, Elpida, Albach, Fredrik N. ORCID: https://orcid.org/0000-0002-2697-9080, Biesen, Robert, Drzeniek, Norman Michael, Dzamukova, Maria, Haase, Isabell, Søndergaard, Klaus, Schleser, Dorothea, Fiebig, Leonard, Sattler, Arne, Minopoulou, Ioanna, Rehm, Marie Chiara, Kremer, Phillip, Schneider, Udo, Trezzini, Sofia, Rein, Anna Maria Claire, Mayer, Clara Marisa, Doellinger, Felix, Furth, Christian, Staeck, Anja, Cheng, Qingyu, Sinzinger, Benedikt, Unterwalder, Nadine, Ohrndorf, Sarah, Probst, Meike, Li, Yaosi, Grund, Daniel, Walter-Rittel, Thula, Fleischmann, Anja, Wiebe, Edgar, Hütter-Krönke, Marie Luise, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Krönke, Jan, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Kleyer, Arnd, Pecher, Ann-Christin, Henes, Jörg, Troldborg, Anne, Hauser, Anja Erika, Kötter, Ina, Krusche, Martin, Krönke, Gerhard, Alexander, Tobias ORCID: https://orcid.org/0000-0003-1193-0097 and Simon, David
Annals of the Rheumatic Diseases
18 June 2026
(In Press)
Cytokine-mediated activation of kidney-infiltrating CD8(+) T cells enables their contribution to inflammation in human lupus nephritis.
Skopnik, Christopher M., Klocke, Jan, Freund, Paul, Metzke, Diana, Ostendorf, Lennard, Bunse, Mario ORCID: https://orcid.org/0000-0002-7554-2520, Prskalo, Luka, Kotzbauer, Johanna, Hinze, Christian ORCID: https://orcid.org/0000-0003-2526-1621, Grothgar, Emil, Goerlich, Nina, Wagner, Leonie, Daniel, Christoph, Hartmann, Arndt, Schneider, Udo, Biesen, Robert, Alexander, Tobias, Hauser, Anja E., Radbruch, Andreas, Eckardt, Kai-Uwe, Hiepe, Falk, Kruglov, Andrey, Mashreghi, Mir-Farzin and Enghard, Philipp
Science Translational Medicine 18
(857): eadz2015.
8 July 2026
Novel mouse reporter models for the detection of genome editing events in vivo.
Snow, Kathy J. ORCID: https://orcid.org/0009-0006-5565-0619, Saville, Ethan ORCID: https://orcid.org/0009-0001-6564-5753, Heffner, Caleb ORCID: https://orcid.org/0000-0002-2631-6201, Gaitan, Yaned ORCID: https://orcid.org/0009-0002-4356-1812, Duryea, Jeffrey ORCID: https://orcid.org/0000-0001-7692-9340, Davis, Tiffany L. ORCID: https://orcid.org/0009-0001-3643-9977, Bechtel, Lawrence, Hannigan, Seth ORCID: https://orcid.org/0009-0004-7521-7439, Low, Benjamin E. ORCID: https://orcid.org/0000-0003-0350-4602, Rossius, Jana ORCID: https://orcid.org/0009-0000-6011-9714, Dang, Tu ORCID: https://orcid.org/0009-0001-0138-7599, Kulhankova, Katarina ORCID: https://orcid.org/0000-0001-7189-2323, Cheng, Anna X. ORCID: https://orcid.org/0000-0003-1727-9485, Wiles, Michael V. ORCID: https://orcid.org/0000-0002-3620-8386, Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410, McCray, Paul B. ORCID: https://orcid.org/0000-0002-4067-577X, Guay, David ORCID: https://orcid.org/0000-0003-0508-1703, Lutz, Cathleen M. ORCID: https://orcid.org/0000-0003-2502-1900, Bergstrom, David E. ORCID: https://orcid.org/0000-0003-0352-5411, Kuehn, Ralf ORCID: https://orcid.org/0000-0003-1694-9803 and Murray, Stephen A. ORCID: https://orcid.org/0000-0002-0594-1702
bioRxiv
: 2026.04.29.721708.
2 May 2026
Strong constitutive NF-κB signaling in B cells drives SLL/CLL-like lymphomagenesis and overcomes microenvironmental dependencies.
Soberón, Valeria, Osswald, Lena, Moore, Andrew, Sosnowska, Dominika, Swinerd, Gene ORCID: https://orcid.org/0000-0001-9644-9109, Chen, Jingyu, Baygün, Seren ORCID: https://orcid.org/0000-0002-3198-7632, Diehl, Carina, Seyhan, Gönül ORCID: https://orcid.org/0000-0002-3879-8009, Kraus, Laura, Gölling, Vanessa, Trapp, Ricarda, O'Neill, Thomas J. ORCID: https://orcid.org/0000-0003-2253-3118, Bortoluzzi, Sabrina, Kovacs, Daniel, Ammon, Tim, Singroul, Pankaj ORCID: https://orcid.org/0000-0001-9855-1828, Hubarzhevska, Yuliia, Öllinger, Rupert ORCID: https://orcid.org/0000-0002-2292-5982, Mueller, Sebastian ORCID: https://orcid.org/0009-0008-1514-3027, Baranov, Olga, Giansanti, Piero ORCID: https://orcid.org/0000-0003-2857-0841, Gillhuber, Felix ORCID: https://orcid.org/0009-0007-9271-4340, Grath, Sonja ORCID: https://orcid.org/0000-0003-3621-736X, Weigert, Oliver ORCID: https://orcid.org/0000-0002-0987-7373, Rosenwald, Andreas, Sasaki, Yoshiteru, Rajewsky, Klaus ORCID: https://orcid.org/0000-0002-6633-6370, Steiger, Katja ORCID: https://orcid.org/0000-0002-7269-5433, Bassermann, Florian ORCID: https://orcid.org/0000-0003-4435-2609, Rad, Roland ORCID: https://orcid.org/0000-0002-6849-9659, Krappmann, Daniel ORCID: https://orcid.org/0000-0001-7640-3234, Ringshausen, Ingo and Schmidt-Supprian, Marc ORCID: https://orcid.org/0000-0002-8543-6166
Leukemia 40
(3): 522-539.
March 2026
Histone H3 acetylation at Sox1ot promoter by targeted epigenome editing augments proliferation of intermediate progenitors in developing cortex.
Sokpor, Godwin ORCID: https://orcid.org/0000-0002-7120-0793, Ulmke, Pauline Antonie, Nguyen, Hoang Duy, Pham, Linh, Kakani, Princy, Chu, Van Trung ORCID: https://orcid.org/0000-0003-1327-8696, Arnold, Sebastian J., Brand-Saberi, Beate, Nguyen, Huu Phuc ORCID: https://orcid.org/0000-0001-6139-788X and Tuoc, Tran ORCID: https://orcid.org/0000-0003-2079-7259
Biology 15
(14): 1110.
9 July 2026
Targeting PRMT5 inhibitor-induced adaptation in pancreatic cancer with the RBM39 degrader indisulam.
Spielmann, Valentina ORCID: https://orcid.org/0009-0004-7138-4360, Buchloh, Jonas ORCID: https://orcid.org/0000-0002-9820-3054, Selcen, Selen ORCID: https://orcid.org/0009-0006-4006-4369, Schneider, Carolin ORCID: https://orcid.org/0000-0003-3539-9026, Jansari, Shaishavi ORCID: https://orcid.org/0009-0002-0495-3012, Fang, Xin ORCID: https://orcid.org/0000-0003-2098-6623, Duan, Ningjun ORCID: https://orcid.org/0000-0001-6316-3796, Demirdizen, Engin ORCID: https://orcid.org/0009-0004-9346-7458, Krauß, Lukas ORCID: https://orcid.org/0000-0003-0062-8685, Eggert, Jessica ORCID: https://orcid.org/0009-0006-1588-6205, Siegfried, Geraldine ORCID: https://orcid.org/0000-0002-6346-5206, Fedou, Sandrine ORCID: https://orcid.org/0000-0003-3952-607X, Lenz, Christof ORCID: https://orcid.org/0000-0002-0946-8166, Wieland, Lena ORCID: https://orcid.org/0009-0006-5969-1012, Conradi, Lena-Christin ORCID: https://orcid.org/0000-0002-9488-1018, Reichert, Maximilian ORCID: https://orcid.org/0000-0002-8611-5639, Ellenrieder, Volker ORCID: https://orcid.org/0000-0001-9981-8571, Ghadimi, Michael ORCID: https://orcid.org/0000-0001-8208-1526, Grade, Marian ORCID: https://orcid.org/0000-0001-9527-5362, Hessmann, Elisabeth ORCID: https://orcid.org/0000-0002-9462-1291, Khatib, Abdel-Majid ORCID: https://orcid.org/0000-0001-6957-0384, Braun, Christian J. ORCID: https://orcid.org/0000-0003-1704-6219, Wegwitz, Florian ORCID: https://orcid.org/0000-0003-0750-6998, Saur, Dieter ORCID: https://orcid.org/0000-0001-5874-0210, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872 and Schneider, Günter ORCID: https://orcid.org/0000-0003-1840-4508
Cancer Research Communications 6
(9): 2039-2055.
1 September 2026
Simultaneous auto-transplant and CD19 CAR T-cell 2nd line therapy followed by CD20 × CD3 bispecific antibody for refractory Burkitt lymphoma, a case report.
Stegemann, Maike ORCID: https://orcid.org/0009-0007-3961-9344, Macherndl-Spandl, Sigrid ORCID: https://orcid.org/0009-0007-1247-7948, Mairhofer, Mario ORCID: https://orcid.org/0000-0002-7218-6284, Kaltenbrunner, Sabine ORCID: https://orcid.org/0000-0002-2794-025X, Buxhofer-Ausch, Veronika ORCID: https://orcid.org/0000-0002-7369-9700, Clausen, Johannes ORCID: https://orcid.org/0000-0002-2729-9706, Petzer, Andreas ORCID: https://orcid.org/0000-0003-1595-0300 and Schmitt, Clemens A. ORCID: https://orcid.org/0000-0002-4731-2226
Leukemia & Lymphoma 67
(5): 1147-1151.
April 2026
Dynamics of clonal hematopoiesis and cellular responses to stress-induced toxicity in autologous stem cell transplantation.
Stein, Catarina M. ORCID: https://orcid.org/0000-0002-9015-7671, Hablesreiter, Raphael ORCID: https://orcid.org/0000-0002-4586-932X, Christen, Friederike ORCID: https://orcid.org/0000-0001-8868-2533, Löwe, Pelle, Fustero-Torre, Coral, Kopp, Klara, Locher, Benjamin N., Nitsch, Lena ORCID: https://orcid.org/0000-0003-0775-1969, Altwasser, Robert ORCID: https://orcid.org/0009-0002-6216-6068, Kerschbaum, Johanna Franziska, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164, Strzelecka, Paulina M. ORCID: https://orcid.org/0000-0003-0226-6788 and Damm, Frederik ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 40
(2): 314-324.
February 2026
Single-cell RNA-seq data for murine LSK, LK and total bone marrow cells.
Stäble, S., Schönung, M., Hartmann, M., Hakobyan, M., Krämer, S., Mücke, O., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Mallm, J., Rippe, K., Schlesner, M., Milsom, M.D., Plass, C., Lipka, D.B. and
[Dataset]
9 May 2026
Cell-autonomous control coupled with tissue context regulates the cessation of migration at the site of organ development.
Tarbashevich, Katsiaryna, Labbaf, Zahra, Ophaus, Moritz, Schick, Jan, Kühl, Lucas, Gross-Thebing, Sargon, Reichman-Fried, Michal, Hoffmann, Dennis, Stehling, Martin, Seggewiss, Jochen, Ruckert, Christian, Kroll, Johanna B. ORCID: https://orcid.org/0000-0003-4652-3598, Junker, Jan Philipp ORCID: https://orcid.org/0000-0002-2826-8290 and Raz, Erez ORCID: https://orcid.org/0000-0002-6347-3302
Development 153
(16): dev.205271.
20 February 2026
A protective cGAMP-mediated anti-tumor immune response can proceed without LRRC8/VRAC channels.
Thöne, Fabian M.B. ORCID: https://orcid.org/0009-0002-5191-9351, Polovitskaya, Maya M. ORCID: https://orcid.org/0000-0002-8144-9824, Höpken, Uta E. ORCID: https://orcid.org/0000-0002-0776-4893, Rehm, Armin ORCID: https://orcid.org/0000-0001-7490-1950 and Jentsch, Thomas J. ORCID: https://orcid.org/0000-0002-3509-2553
Journal of Biological Chemistry 302
(2): 111060.
February 2026
Targeting Bruton's tyrosine kinase (BTK) in autoimmunity: achievements, opportunities and challenges.
Torke, Sebastian ORCID: https://orcid.org/0000-0002-1029-3623, Dybowski, Sarah ORCID: https://orcid.org/0000-0001-7762-3255 and Weber, Martin S. ORCID: https://orcid.org/0000-0001-8409-0389
Drug Design Development and Therapy 20
: 568214.
14 July 2026
Real-world data on clinical response to inflammatory bowel disease biological treatments in patients with concurrent primary sclerosing cholangitis: a case-control study.
Tosse, Robert ORCID: https://orcid.org/0009-0009-2742-6988, Maibier, Martin, Fischer, Andreas, Razpotnik, Marcel ORCID: https://orcid.org/0000-0001-8442-1926, Kouladouros, Konstantinos ORCID: https://orcid.org/0000-0001-8294-6673, Tacke, Frank ORCID: https://orcid.org/0000-0001-6206-0226, Sigal, Michael ORCID: https://orcid.org/0000-0003-4772-0761 and Wizenty, Jonas ORCID: https://orcid.org/0000-0003-4261-0416
Gastroenterology Report 14
: goag079.
30 July 2026
Altered cholesterol immunometabolism activates the macrophage NLRP3-inflammasome in lung fibrosis.
Vaso, Mariza, Dukic, Matija, Pennitz, Peter, Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Collum, Scott, Lin, Wanchang, Winder, Catherine L., Dunn, Warwick B., Schupp, Jonas C., Braubach, Peter, Wygrecka, Malgorzata, Ren, Dewei, Suarez, Erik E, Huang, Howard J., Hussain, Rahat, Patel, Bela, Karmouty-Quintana, Harry, Akalin, Altuna ORCID: https://orcid.org/0000-0002-0468-0117, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Nouailles, Geraldine, Ochs, Matthias, Lopez-Rodriguez, Elena and Giambelluca, Sonia
American Journal of Respiratory Cell and Molecular Biology 74
(8): 1114-1124.
August 2026
EMD-53909: Cryo-ET structure of full-length membrane-bound EHD2 complex.
Vazquez-Sarandeses, E. ORCID: https://orcid.org/0009-0003-3526-7629, Mikirtumov, V. ORCID: https://orcid.org/0009-0004-6849-4825, Noel, J. ORCID: https://orcid.org/0000-0003-3168-6036, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
[Dataset]
8 July 2026
EMD-53911: Cryo-ET structure of N-terminally truncated membrane-bound EHD2 complex.
Vazquez-Sarandeses, E. ORCID: https://orcid.org/0009-0003-3526-7629, Mikirtumov, V. ORCID: https://orcid.org/0009-0004-6849-4825, Noel, J. ORCID: https://orcid.org/0000-0003-3168-6036, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
[Dataset]
8 July 2026
Non-temperature-induced antitumor effects of amplitude-modulated radiofrequency: molecular and functional synergies with radiotherapy.
Veltsista, Paraskevi D., Walther, Wolfgang ORCID: https://orcid.org/0000-0003-2360-1370, Torke, Sebastian ORCID: https://orcid.org/0000-0002-1029-3623, Ivanov, Andranik ORCID: https://orcid.org/0000-0002-4824-1925, Dieper, Anna, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Zips, Daniel, Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X and Ghadjar, Pirus
Cancers 18
(10): 1613.
May 2026
9RBU: Cryo-ET structure of full-length membrane-bound EHD2 complex.
Vázquez-Sarandeses, E. ORCID: https://orcid.org/0009-0003-3526-7629, Mikirtumov, V. ORCID: https://orcid.org/0009-0004-6849-4825, Noel, J. ORCID: https://orcid.org/0000-0003-3168-6036, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
[Dataset]
8 July 2026
Structures of EHD2 filaments on curved membranes provide a model for caveolar neck stabilization.
Vázquez-Sarandeses, Elena ORCID: https://orcid.org/0009-0003-3526-7629, Mikirtumov, Vasilii ORCID: https://orcid.org/0009-0004-6849-4825, Noel, Jeffrey K. ORCID: https://orcid.org/0000-0003-3168-6036, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414
Nature Communications 17
(1): 7621.
31 July 2026
Immune–proteo–metabolomic changes link to Aβ and tau pathology in Alzheimer disease.
Wang, Meng, Buthut, Maria, Meinhardt, Jenny, Otto, Carolin, Gallaccio, Gerardina ORCID: https://orcid.org/0000-0002-1060-5244, Fernández-Zapata, Camila ORCID: https://orcid.org/0000-0003-4795-6053, Teves, Matteo, Samol, Claudia, Dettmer, Katja, Heckscher, Simon, Kamboj, Sakshi, Bahar, Yozlem, Conrad, Christian, Böttcher, Christian, Kunkel, Desiree, Ruprecht, Klemens, Paul, Friedemann ORCID: https://orcid.org/0000-0002-6378-0070, Oefner, Peter J., Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Gronwald, Wolfram, Prüß, Harald and Böttcher, Chotima ORCID: https://orcid.org/0000-0002-6226-586X
Alzheimer's & Dementia 22
(4): e71359.
April 2026
Global quantification of mammalian gene expression noise.
Welter, Anna Sophie ORCID: https://orcid.org/0009-0003-9846-3889, Mutschler, Florian ORCID: https://orcid.org/0009-0002-0992-7171, Simon, Mareike ORCID: https://orcid.org/0000-0001-7213-9499, Giacomelli, Chiara ORCID: https://orcid.org/0000-0003-1466-1371, Branscheid, Ann-Christin, Manukyan, Artur ORCID: https://orcid.org/0000-0002-0441-9517, Teixeira Alves, Luiz Gustavo ORCID: https://orcid.org/0000-0002-5822-4168, Gerwien, Maximilian ORCID: https://orcid.org/0000-0002-2884-4155, Kerridge, Robert, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868 and Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751
bioRxiv
: 2026.05.11.724258.
14 May 2026
Processed data and code for Manuscript: Global quantification of mammalian gene expression noise.
Welter, Anna Sopie ORCID: https://orcid.org/0009-0003-9846-3889, Mutschler, Florian ORCID: https://orcid.org/0009-0002-0992-7171, Simon, Mareike ORCID: https://orcid.org/0000-0001-7213-9499, Giacomelli, Chiara ORCID: https://orcid.org/0000-0003-1466-1371, Branscheid, Ann-Christin, Manukyan, Artur ORCID: https://orcid.org/0000-0002-0441-9517, Teixeira Alves, Luiz Gustavo ORCID: https://orcid.org/0000-0002-5822-4168, Gerwien, Maximilian ORCID: https://orcid.org/0000-0002-2884-4155, Kerridge, Robert, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868 and Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751
[Dataset]
14 May 2026
CXCR4-targeted molecular imaging in hematology and oncology.
Werner, Rudolf A., Buck, Andreas K., Haug, Alexander, Kraeber-Bodéré, Francoise, Lapa, Constantin, Schottelius, Margret, Serfling, Sebastian E., Higuchi, Takahiro, Bodet-Milin, Caroline, Raderer, Markus, Wegen, Simone, Pomper, Martin G., Deroose, Christophe M., Herrmann, Ken, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Kobe, Carsten and Gotthardt, Martin
Journal of Nuclear Medicine
13 August 2026
(In Press)
Mutated FGFR1 is an oncogenic driver and therapeutic target in high-risk neuroblastoma.
Werr, Lisa, Boland, Jana, Petersen, Josephine, Iglesias, Fiorella, Höppner, Stefanie, Bartenhagen, Christoph, Rosswog, Carolina, Hellmann, Anna-Maria, Kahlert, Yvonne, Hemstedt, Nadine, Ibruli, Nadliv, Dammert, Marcel A., Decarolis, Boris, Werner, Jan-Michael, Malchers, Florian, Schramm, Kathrin, Witt, Olaf, Beiske, Klaus Hermann, Rognlien, Anne Gro Wesenberg, Gunnes, Maria Winther, Langenberg, Karin Ps, Molenaar, Jan, Bernkopf, Marie, Taschner-Mandl, Sabine, Hughes, Debbie, George, Sally L., Chesler, Louis, Schulte, Johannes H., Barone, Giuseppe, Capasso, Mario, Surrey, Lea F., Bagatell, Rochelle, Masliah-Planchon, Julien, Schleiermacher, Gudrun, Grüll, Holger, Westermann, Frank, Schultheis, Anne M., Büttner, Reinhard, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, Angelika, Peifer, Martin, Shukla, Neerav N., Simon, Thorsten, Hero, Barbara, Reinhardt, H. Christian, Thomas, Roman K. and Fischer, Matthias
Journal of Clinical Investigation 136
(7): e189152.
1 April 2026
Efficacy and safety of bridging therapy prior to CAR T-cell therapy in relapsed or refractory multiple myeloma.
Wesener, Marie Christine, Demel, Uta Margareta ORCID: https://orcid.org/0000-0002-6480-4185, Pabst, Thomas, Teipel, Raphael, Albici, Anca-Maria, Von Tresckow, Bastian, Teichert, Marcel, Boquoi, Amelie, Holderried, Tobias, Schmitz, Friederike, Müller, Fabian, Rößiger, Friedrich-Linus, Hoffmann, Michele, Schub, Natalie, Tovar, Natalia, Oliver-Caldes, Aina, Kröger, Nicolaus, Baermann, Ben-Niklas, Bohl, Stephan, Fandrei, David, Vucinic, Vladan, Strassl, Irene, Stölzel, Friedrich, De Larrea, Carlos Fernández, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Merz, Maximilian and Gagelmann, Nico
Haematologica
3 September 2026
(In Press)
Clonal hematopoiesis and lymphoma-associated mutations in hematopoietic progenitors in B-cell non-Hodgkin lymphoma.
Wiegand, Laura, Silva, Patricia, Noerenberg, Daniel, Christen, Friederike, Kopp, Klara, Locher, Benjamin Nick, Löwe, Pelle, Tilgner, Marlon, Altwasser, Robert ORCID: https://orcid.org/0009-0002-6216-6068, Storzer, Vanessa, Stein, Catarina Marlene, Briest, Franziska, Arends, Christopher Maximilian, Frick, Mareike, Ihlow, Jana, Dolnik, Anna, Ishaque, Naveed ORCID: https://orcid.org/0000-0002-8426-901X, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Na, Il-Kang ORCID: https://orcid.org/0000-0001-9902-5424, Penter, Livius ORCID: https://orcid.org/0000-0002-9060-0207, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Hablesreiter, Raphael and Damm, Frederik
Blood 147
(15): 1723-1734.
9 April 2026
Human organoids: fit for drug discovery?
Wittich, Annika, Krieg, Kim, Gribbon, Philip, Metzger, Jakob J. ORCID: https://orcid.org/0000-0001-6813-4425, Prigione, Alessandro and Pless, Ole
Stem Cell Reports 21
(6): 102898.
9 June 2026
Aging and the microbiome: precondition for gastrointestinal carcinogenesis.
Wizenty, Jonas and Sigal, Michael ORCID: https://orcid.org/0000-0003-4772-0761
Best Practice & Research Clinical Gastroenterology
: 102122.
15 July 2026
(In Press)
A recipe for chaos: extrachromosomal DNA and the hallmarks of cancer.
Wong, Ivy Tsz-Lo, Bailey, Chris, Wu, Sihan, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Cravatt, Benjamin F., Chen, Zhijian J., Bafna, Vineet, Jamal-Hanjani, Mariam, Swanton, Charlie, Chang, Howard Y. and Mischel, Paul S.
Cell 189
(8): 2307-2321.
16 April 2026
Integrating UHPLC-MS and MALDI-MSI for spatial nucleoside profiling in FFPE breast cancer: a multimodal molecular pathology framework.
Wu, Jierong ORCID: https://orcid.org/0000-0002-2413-0411, Geisberger, Sabrina Y. ORCID: https://orcid.org/0000-0001-6477-1312, Mastrobuoni, Guido ORCID: https://orcid.org/0000-0003-4509-1295, Lisek, Kamil ORCID: https://orcid.org/0000-0002-2406-8830, Raimundo, Sandra ORCID: https://orcid.org/0009-0000-3353-5456, Nebrich, Grit, Grzeski, Marta, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Klauschen, Frederick ORCID: https://orcid.org/0000-0002-9131-2389, Klein, Oliver ORCID: https://orcid.org/0000-0001-7984-7607 and Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299
bioRxiv
: 2026.01.28.701949.
30 January 2026
50 Jahre Protoonkogene [50 years of proto-oncogenes].
Wunderlich, Volker
BIOspektrum 32
(4): 483-485.
June 2026
Complex human hear bearing skin organoids reveal cell type specific susceptibility and innate immune responses to Herpes Simplex Virus 1.
Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Albertini, Silvia ORCID: https://orcid.org/0000-0002-8540-5378, Friedel, Caroline C. ORCID: https://orcid.org/0000-0003-3569-4877, Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Winterfeldt, Annalena, Bracker, Nina, Huang, Jiabin ORCID: https://orcid.org/0000-0002-3480-7115, Krasemann, Susanne ORCID: https://orcid.org/0000-0001-8795-818X, Plumbon, Izabela ORCID: https://orcid.org/0009-0006-3720-3700, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Reimer, Rudolph, Schneider, Carola, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Hafezi, Wali, Hansen, Arne, Grundhoff, Adam ORCID: https://orcid.org/0000-0003-0940-7045, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Fischer, Nicole ORCID: https://orcid.org/0000-0002-5092-8179 and Czech-Sioli, Manja ORCID: https://orcid.org/0000-0002-7720-3282
bioRxiv
: 2025.02.10.637415v2.
12 January 2026
Interferon-independent STING enforces epithelial genome-integrity checkpoint to restrain tumor evolution.
Xiang, Hang, Macino, Martina ORCID: https://orcid.org/0000-0002-8730-9005, Woitaske-Proske, Clemens, Bodenstein, Nicholas, Bernardes, Joana P., Tran, Florian, Schmid, Nicole A., Martini, Gabriela Rios, Wotawa, Felix, Bornhaeuser, Johanna, Kakavand, Nassim, Dyck Dionisi, Oliver ORCID: https://orcid.org/0000-0002-0410-1736, van den Bossche, Silke, Yang, Guang, Wu, Qicong, Kugler, Julia, Welz, Lina, Konukiewitz, Bjorn, Fischer, Julius C., Peifer, Christian, Schreiber, Stefan, Rosenstiel, Philip, Tschurtschenthaler, Markus ORCID: https://orcid.org/0000-0002-0060-4790, Sanders, Ashley D. ORCID: https://orcid.org/0000-0003-3945-0677 and Aden, Konrad ORCID: https://orcid.org/0000-0003-3482-7316
bioRxiv
: 2026.02.17.706442v2.
25 March 2026
Cellular heterogeneity during arterial aging.
Xu, He, Mendez, Paul-Lennard ORCID: https://orcid.org/0000-0003-2025-7981, Kasakovski, Dimitri and Sluimer, Judith
Aging Cell 25
(7): e70597.
July 2026
The IBEX knowledge-base a community resource enabling adoption and development of immunofluorescence imaging methods.
Yaniv, Ziv, Anidi, Ifeanyichukwu U., Arakkal, Leanne, Arroyo-Mejías, Armando J., Beuschel, Rebecca T., Börner, Katy, Chu, Colin J., Clark, Beatrice, Clatworthy, Menna R., Colautti, Jake, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Croteau, Joshua, Denha, Saven, Dever, Rose, Dutra, Walderez O., Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Fullam, Spencer, Gerner, Michael Y., Gola, Anita, Gollob, Kenneth J., Hernandez, Jonathan M., Hor, Jyh Liang, Ichise, Hiroshi, Jing, Zhixin, Jonigk, Danny, Kandov, Evelyn, Kastenmüller, Wolfgang, Koenig, Joshua F.E., Kothurkar, Aanandita, Kortekaas, Rosa K., Kreins, Alexandra Y., Lamborn, Ian T., Lin, Yuri, Morais, Katia Luciano Pereira, Lunich, Aleksandra, Luz, Jean C.S., MacDonald, Ryan B., Makranz, Chen, Maltez, Vivien I., McDonough, John E., Moriarty, Ryan V., Ocampo-Godinez, Juan M., Olyntho, Vitoria M., Oxenius, Annette, Padhan, Kartika, Remmert, Kirsten, Richoz, Nathan, Schrom, Edward C., Shang, Wanjing, Shi, Lihong, Shih, Rochelle M., Speranza, Emily, Stierli, Salome, Teichmann, Sarah A., Veres, Tibor Z., Vierhout, Megan, Wachter, Brianna T., Wade-Vallance, Adam K., Williams, Margaret, Zangger, Nathan, Germain, Ronald N. and Radtke, Andrea J.
eLife 14
: RP105737.
23 January 2026
A Distinct CAR-T Cell Phenotype Mediates Therapeutic Response at Limited Doses.
Yousefian, Schayan ORCID: https://orcid.org/0000-0003-0902-0369
[Dataset]
17 July 2026
A distinct CAR-T cell phenotype mediates therapeutic response at limited doses.
Yousefian, Schayan ORCID: https://orcid.org/0000-0003-0902-0369, Schubert, Maria-Luisa, Minafra, Anna Rita, Derigs, Patrick ORCID: https://orcid.org/0000-0002-4670-8851, Gräßle, Sarah ORCID: https://orcid.org/0000-0002-5260-6392, Horne, Arik ORCID: https://orcid.org/0000-0002-4209-4573, Demel, Uta M. ORCID: https://orcid.org/0000-0002-6480-4185, Liebaert, Julian ORCID: https://orcid.org/0009-0009-7547-1222, Röthemeier, Caroline, Pupp, Franziska ORCID: https://orcid.org/0009-0009-4883-3275, Höpken, Uta E. ORCID: https://orcid.org/0000-0002-0776-4893, Krönke, Jan ORCID: https://orcid.org/0000-0002-4649-0506, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Schmitt, Anita, Hübschmann, Daniel ORCID: https://orcid.org/0000-0002-6041-7049, Müller-Tidow, Carsten ORCID: https://orcid.org/0000-0002-7166-5232, Dreger, Peter, Schmitt, Michael ORCID: https://orcid.org/0000-0002-1579-1509 and Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051
Nature Communications 17
(1): 7589.
29 July 2026
quantmsdiann: a scalable SDRF-driven DIA-NN workflow for reanalysis of single-cell, spatial, and bulk proteomics datasets.
Yue, Qi-Xuan ORCID: https://orcid.org/0009-0004-8120-9339, Shen, Yufei, Dai, Chengxin ORCID: https://orcid.org/0000-0001-6943-5211, Larrea-Sebal, Asier ORCID: https://orcid.org/0000-0001-9107-4299, Webel, Henry ORCID: https://orcid.org/0000-0001-8833-7617, Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Kok, Orhun, Slavov, Nikolai ORCID: https://orcid.org/0000-0003-2035-1820, Vizcaíno, Juan Antonio ORCID: https://orcid.org/0000-0002-3905-4335, Sachsenberg, Timo ORCID: https://orcid.org/0000-0002-2833-6070, Bai, Mingze ORCID: https://orcid.org/0000-0002-9782-2056, Demichev, Vadim ORCID: https://orcid.org/0000-0002-2424-9412 and Perez-Riverol, Yasset ORCID: https://orcid.org/0000-0001-6579-6941
Research Square
: rs-10319687/v1.
14 July 2026
DeBCR: a deep learning framework for microscopy image enhancement (Napari GUI).
Yushkevich, Artsemi ORCID: https://orcid.org/0000-0002-8729-9281, Li, Rui ORCID: https://orcid.org/0000-0002-3085-5267, Chu, Xiaofeng ORCID: https://orcid.org/0000-0001-6801-3949, Kudryashev, Misha ORCID: https://orcid.org/0000-0003-3550-6274 and Manukyan, Artur ORCID: https://orcid.org/0000-0002-0441-9517
[Dataset]
18 February 2026
DeBCR: a deep learning framework for microscopy image enhancement (Python API).
Yushkevich, Artsemi ORCID: https://orcid.org/0000-0002-8729-9281, Li, Rui ORCID: https://orcid.org/0000-0002-3085-5267, Chu, Xiaofeng ORCID: https://orcid.org/0000-0001-6801-3949, Kudryashev, Misha ORCID: https://orcid.org/0000-0003-3550-6274 and Manukyan, Artur ORCID: https://orcid.org/0000-0002-0441-9517
[Dataset]
18 February 2026
An integrated landscape of mRNA and protein isoforms.
Zauber, Henrik ORCID: https://orcid.org/0000-0003-2595-1147 and Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751
[Dataset]
7 July 2026
MACC1 hyperactivates receptor tyrosine kinase signaling through phosphorylation-dependent adaptor activity in colorectal cancer cells.
Zincke, Fabian, Kobelt, Dennis ORCID: https://orcid.org/0000-0002-9373-0648, Kläger, Susan, Pachl, Fiona, Erdmann, Gerrit ORCID: https://orcid.org/0000-0002-4183-3995, Dahlmann, Mathias ORCID: https://orcid.org/0000-0002-0036-5283, Walther, Wolfgang ORCID: https://orcid.org/0000-0003-2360-1370, Küster, Bernhard ORCID: https://orcid.org/0000-0002-9094-1677 and Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X
Biomolecules 16
(9): 1267.
September 2026
Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy.
Zink, Annika ORCID: https://orcid.org/0000-0002-8489-6339, Dai, Dao-Fu, Wittich, Annika, Henke, Marie-Thérèse ORCID: https://orcid.org/0000-0001-6572-1667, Pedrotti, Giulia, Heiduschka, Sonja, Santamaria, Guillem, Pentimalli, Tancredi Massimo ORCID: https://orcid.org/0000-0002-8461-7918, Brueser, Christian, Notopoulou, Sofia, Umar, Abdul Rahim, Zhaivoron, Aleksandra, Petersilie, Laura, Jerred, Caleb, Bergmans, Jesper, Neu, Louis Anton, Schumacher, Fabian, Keller-Findeisen, Jan, Rybak-Wolf, Agnieszka ORCID: https://orcid.org/0000-0002-1192-5290, Stach, Daniel, Reinshagen, Jeanette, Haferkamp, Undine, Krieg, Kim, Zaliani, Andrea, Euro, Liliya, Di Donfrancesco, Alessia, Santanatoglia, Chiara, Cappellozza, Enrica, Suarez Cubero, Marta, Pavez-Giani, Mario, Bakumenko, Oleh, Meierhofer, David, Foley, Alan, Morales-Gonzalez, Susanne, Tolle, Isabella, Herebian, Diran, Bonesso, Daniele, Cecchetto, Giulia, Wong, Sakurako Nagumo, Moresco, Monica, Maresca, Alessandra, Decimo, Ilaria, De Sanctis, Francesco, Adamo, Annalisa, Adjobo-Hermans, Merel J.W., Duchi, Roberto, Barandalla, Maria, Scaglia, Marco, Perota, Andrea, Galli, Cesare, Kleuser, Burkhard, Cyganek, Lukas, Mühlhausen, Chris, Schlotawa, Lars, Tiranti, Valeria, Mayatepek, Ertan, Szabo, Ildiko, La Morgia, Chiara, Klopstock, Thomas, Carelli, Valerio, Distelmaier, Felix, Rossi, Andrea, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Ullah, Ghanim, Jakobs, Stefan, Rose, Christine R., Petrakis, Spyros, Edenhofer, Frank, Koopman, Werner J.H., Lisowski, Pawel ORCID: https://orcid.org/0000-0002-3634-1072, Suomalainen, Anu, Brunetti, Dario, Del Sol, Antonio, Bottani, Emanuela, Pless, Ole ORCID: https://orcid.org/0000-0002-1468-316X, Schuelke, Markus ORCID: https://orcid.org/0000-0003-2824-3891 and Prigione, Alessandro ORCID: https://orcid.org/0000-0001-9457-1952
Cell 189
(6): 1656-1679.e42.
19 March 2026
Engineered CCR7 overexpression enhances nodal CAR T-cell homing and cytotoxicity toward B-cell lymphoma.
Zschummel, Maria ORCID: https://orcid.org/0000-0002-4778-8742, Bunse, Mario ORCID: https://orcid.org/0000-0002-7554-2520, Spierling, Anna-Lena ORCID: https://orcid.org/0009-0003-0009-7615, Li, Anna ORCID: https://orcid.org/0000-0002-4702-7783, Joedicke, Jara J. ORCID: https://orcid.org/0000-0002-4708-3216, Margineanu, Anca ORCID: https://orcid.org/0000-0002-6634-9729, Blachut, Susanne ORCID: https://orcid.org/0009-0007-0102-9867, Lindberg, Eric Lars-Helge ORCID: https://orcid.org/0000-0002-2979-433X, Ruiz-Orera, Jorge ORCID: https://orcid.org/0000-0002-8317-0034, Hübner, Norbert ORCID: https://orcid.org/0000-0002-1218-6223, Rehm, Armin ORCID: https://orcid.org/0000-0001-7490-1950 and Höpken, Uta E. ORCID: https://orcid.org/0000-0002-0776-4893
Cancer Immunology Research 14
(5): 827-844.
4 May 2026
Highlights from the Susan Lindquist School on Proteostasis-EMBO|FEBS Lecture Course, 16-19 September, 2025, Espoo, Finland.
van Weert, Emile, Giacomelli, Chiara ORCID: https://orcid.org/0000-0003-1466-1371, Stefani, Ioanna, Lopez-Bautista, Maria Li ORCID: https://orcid.org/0009-0000-5620-5644, Neumeier, Antonia-Viktoria, Paul, Pubali, Das, Anushka, Hari, Chetan and Gulgec, Ahmet Sadik ORCID: https://orcid.org/0000-0003-1172-8497
FEBS Letters 600
(3): 271-281.
February 2026
2025
Helmholtz Health task force to strengthen prevention research and its translation globally.
Nature Medicine 31
(5): 1386-1387.
May 2025
The deubiquitinase OTUD7B ameliorates central nervous system autoimmunity by inhibiting degradation of glial fibrillary acidic protein and astrocyte hyperinflammation (house mouse).
[Dataset]
10 January 2025
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing.
Abay, T., Stickels, R.R. ORCID: https://orcid.org/0000-0003-4326-4084, Takizawa, M.T., Nalbant, B.N., Hsieh, Y.H. ORCID: https://orcid.org/0000-0003-3037-8728, Hwang, S., Snopkowski, C., Yu, K.K.H. ORCID: https://orcid.org/0000-0002-2394-4990, Abou-Mrad, Z. ORCID: https://orcid.org/0000-0001-6387-8396, Tabar, V. ORCID: https://orcid.org/0000-0002-1284-1670, Howitt, B.E ORCID: https://orcid.org/0000-0002-0309-6680, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Chaligné, R. ORCID: https://orcid.org/0000-0003-4332-3291, Satpathy, A.T ORCID: https://orcid.org/0000-0002-5167-537X and Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807
Nature Genetics 57
(2): 451-460.
February 2025
Clonal driver neoantigen loss under EGFR TKI and immune selection pressures.
Al Bakir, M. ORCID: https://orcid.org/0000-0002-0846-8332, Reading, J.L. ORCID: https://orcid.org/0000-0001-5381-978X, Gamble, S., Rosenthal, R., Uddin, I., Rowan, A., Przewrocka, J., Rogers, A. ORCID: https://orcid.org/0000-0002-7071-7889, Wong, Y.N.S., Bentzen, A.K., Veeriah, S., Ward, S. ORCID: https://orcid.org/0000-0002-6777-5279, Garnett, A.T., Kalavakur, P., Martínez-Ruiz, C. ORCID: https://orcid.org/0000-0002-4817-0565, Puttick, C. ORCID: https://orcid.org/0009-0006-3022-8737, Huebner, A. ORCID: https://orcid.org/0000-0001-8009-4999, Cook, D.E. ORCID: https://orcid.org/0000-0003-3347-562X, Moore, D.A. ORCID: https://orcid.org/0000-0002-6296-1312, Abbosh, C., Hiley, C.T., Naceur-Lombardelli, C. ORCID: https://orcid.org/0000-0002-7097-0307, Watkins, T.B.K., Petkovic, M. ORCID: https://orcid.org/0000-0003-2875-216X, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Gálvez-Cancino, F. ORCID: https://orcid.org/0000-0001-8417-1891, Litchfield, K. ORCID: https://orcid.org/0000-0002-3725-0914, Meldgaard, P. ORCID: https://orcid.org/0000-0002-5788-4463, Sorensen, B.S. ORCID: https://orcid.org/0000-0002-9472-8099, Madsen, L.B., Jäger, D., Forster, M.D., Arkenau, T., Domingo-Vila, C., Tree, T.I.M., Kadivar, M. ORCID: https://orcid.org/0000-0003-1499-191X, Hadrup, S.R. ORCID: https://orcid.org/0000-0002-5937-4344, Chain, B. ORCID: https://orcid.org/0000-0002-7417-3970, Quezada, S.A. ORCID: https://orcid.org/0000-0002-9763-1700, McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045 and Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018
Nature 639
(639): 639.
27 March 2025
Targeting autoimmunity with CD19-CAR T-cell therapy: efficacy and seroconversion in diffuse systemic sclerosis and rheumatoid arthritis.
Albach, F.N., Minopoulou, I., Wilhelm, A., Biesen, R. ORCID: https://orcid.org/0000-0002-0434-7832, Kleyer, A., Wiebe, E. ORCID: https://orcid.org/0000-0002-3600-0788, Fleischmann, A., Frick, M., Damm, F., Gogolok, J., Serve, S., Locher, B.N., Borie, D., Casteleyn, V., Siegert, E., Dörner, T., Alexander, T., Furth, C., Zernicke, J., Movassaghi, K., Hütter-Krönke, M.L., Schrezenmeier, E. ORCID: https://orcid.org/0000-0002-0016-7885, Schneider, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Krönke, G., Penack, O. and Simon, D.
Rheumatology 64
(6): 4075-4077.
June 2025
Investigating genetic modifications to enhance L1CAM-CAR T cell migration in solid tumors in a 3D bioprinted neuroblastoma model.
Andersch, Lena, Grunewald, Laura, Stecklum, Maria, Klironomos, Filippos, Haase, Kerstin ORCID: https://orcid.org/0000-0002-0944-5618, Hollek, Viola, Lam, Tobias, Jung, Beate Anahita, Winkler, Anika, Schwiebert, Silke, Astrahantseff, Kathy, Launspach, Michael, Jens, Marvin ORCID: https://orcid.org/0000-0002-6660-8743, Henssen, Anton ORCID: https://orcid.org/0000-0003-1534-778X, Kloke, Lutz, Blüthgen, Nils ORCID: https://orcid.org/0000-0002-0171-7447, Eggert, Angelika, Schulte, Johannes H. ORCID: https://orcid.org/0000-0003-0671-1201, Anders, Kathleen ORCID: https://orcid.org/0000-0002-0429-200X and Künkele, Annette
Frontiers in Immunology 16
: 1677361.
27 November 2025
Growth differentiation factor-15: a promising biomarker and target in cancer patients.
Anker, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Khan, M.S.
JACC: CardioOncology 7
(2): 153-156.
February 2025
New cardiovascular biomarkers in patients with advanced cancer – a prospective study comparing MR-proADM, MR-proANP, copeptin, high-sensitivity troponin T and NT-proBNP.
Anker, M.S. ORCID: https://orcid.org/0000-0002-4406-8555, Lück, L.C., Khan, M.S., Porthun, J., Hadzibegovic, S., Lena, A., Wilkenshoff, U., Weinländer, P., Evertz, R., Totzeck, M., Mahabadi, A.A., Rassaf, T., Anker, S.D. ORCID: https://orcid.org/0000-0002-4406-8555, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Karakas, M., Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 27
(6): 1047-1055.
June 2025
Clinical and echocardiographic phenotype of cardiac wasting in patients with advanced cancer.
Anker, Markus S. ORCID: https://orcid.org/0000-0002-4406-8555, Khan, Muhammad Shahzeb, Nikolski, Anja, Porthun, Jan, Arshad, Muhammad Sameer, Hadzibegovic, Sara, Lena, Alessia, Kretzler, Lucie, Hella, Jonathan L., Witkowski, Marco, Rieger, Kathrin, Ahn, Johann, Modest, Dominik P., Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Totzeck, Matthias, Mahabadi, Amir A., Rassaf, Tienush, Buchmann, Nikolaus, Attanasio, Philipp, Zeller, Tanja, Karakas, Mahir, Tocchetti, Carlo G., Wilkenshoff, Ursula, Cleland, John G.F., von Haehling, Stephan, Butler, Javed and Landmesser, Ulf
European Journal of Heart Failure 27
(11): 2130-2140.
November 2025
Randomized investigation of heart failure therapy in patients with advanced cancer at risk of cardiac wasting: rationale and design of the EMPATICC trial.
Anker, Markus S. ORCID: https://orcid.org/0000-0002-4406-8555, Mahabadi, Amir A., Totzeck, Matthias, Tewes, Mitra, Mincu, Raluca, Khan, Muhammad Shahzeb, Butler, Javed, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Ahn, Johann, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Modest, Dominik P., Landmesser, Ulf, Lehmann, Lorenz H., Bercker, Sven, Laufs, Ulrich, Böhm, Michael, Merkely, Bela, Diek, Monika, Heise, Tim, Hellmich, Martin, Placzek, Marius, Friede, Tim ORCID: https://orcid.org/0000-0001-5347-7441, Anker, Stefan D. and Rassaf, Tienush
European Journal of Heart Failure 27
(10): 1905-1917.
October 2025
Optimized HF therapy in patients with advanced cancer in palliative care: dosing strategies from the EMPATICC trial.
Anker, Markus S., Shahzeb Khan, Muhammad, Mahabadi, Amir A., Totzeck, Matthias, Tewes, Mitra, Arshad, Muhammad Sameer, Mincu, Raluca, Butler, Javed, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Ahn, Johann, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Modest, Dominik P., Landmesser, Ulf, Lehmann, Lorenz H., Bercker, Sven, Laufs, Ulrich, Böhm, Michael, Merkely, Bela, Diek, Monika, Heise, Tim, Hellmich, Martin, Placzek, Marius, Friede, Tim, Anker, Stefan D. and Rassaf, Tienush
Global Cardiology 3
(3): 3-9.
30 September 2025
Additional file 10 of ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia.
Anwar, Rabia, Pande, Amit ORCID: https://orcid.org/0009-0008-0826-973X, Singh, Manvendra ORCID: https://orcid.org/0000-0002-8626-5418, Huang, Zhi ORCID: https://orcid.org/0000-0002-8993-4912, Hallett, Eve ORCID: https://orcid.org/0009-0002-8268-8074, Xie, Yiran, Gellhaus, Alexandra, Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134, Nonn, Olivia ORCID: https://orcid.org/0000-0001-6385-2866, Gauster, Martin, Raskó, Tamás, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Verlohren, Stefan ORCID: https://orcid.org/0000-0003-3507-8636, Staff, Anne Cathrine, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Pecks, Ulrich, Blois, Sandra M. ORCID: https://orcid.org/0000-0002-0434-2660, Hurst, Laurence D. and Izsvák, Zsuzsanna ORCID: https://orcid.org/0000-0002-2053-2384
[Dataset]
5 November 2025
Additional file 11 of ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia.
Anwar, Rabia, Pande, Amit ORCID: https://orcid.org/0009-0008-0826-973X, Singh, Manvendra ORCID: https://orcid.org/0000-0002-8626-5418, Huang, Zhi ORCID: https://orcid.org/0000-0002-8993-4912, Hallett, Eve ORCID: https://orcid.org/0009-0002-8268-8074, Xie, Yiran, Gellhaus, Alexandra, Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134, Nonn, Olivia ORCID: https://orcid.org/0000-0001-6385-2866, Gauster, Martin, Raskó, Tamás, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Verlohren, Stefan ORCID: https://orcid.org/0000-0003-3507-8636, Staff, Anne Cathrine, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Pecks, Ulrich, Blois, Sandra M. ORCID: https://orcid.org/0000-0002-0434-2660, Hurst, Laurence D. and Izsvák, Zsuzsanna ORCID: https://orcid.org/0000-0002-2053-2384
[Dataset]
5 November 2025
Additional file 2 of ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia.
Anwar, Rabia, Pande, Amit ORCID: https://orcid.org/0009-0008-0826-973X, Singh, Manvendra ORCID: https://orcid.org/0000-0002-8626-5418, Huang, Zhi ORCID: https://orcid.org/0000-0002-8993-4912, Hallett, Eve ORCID: https://orcid.org/0009-0002-8268-8074, Xie, Yiran, Gellhaus, Alexandra, Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134, Nonn, Olivia ORCID: https://orcid.org/0000-0001-6385-2866, Gauster, Martin, Raskó, Tamás, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Verlohren, Stefan ORCID: https://orcid.org/0000-0003-3507-8636, Staff, Anne Cathrine, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Pecks, Ulrich, Blois, Sandra M. ORCID: https://orcid.org/0000-0002-0434-2660, Hurst, Laurence D. and Izsvák, Zsuzsanna ORCID: https://orcid.org/0000-0002-2053-2384
[Dataset]
5 November 2025
Additional file 3 of ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia.
Anwar, Rabia, Pande, Amit ORCID: https://orcid.org/0009-0008-0826-973X, Singh, Manvendra ORCID: https://orcid.org/0000-0002-8626-5418, Huang, Zhi ORCID: https://orcid.org/0000-0002-8993-4912, Hallett, Eve ORCID: https://orcid.org/0009-0002-8268-8074, Xie, Yiran, Gellhaus, Alexandra, Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134, Nonn, Olivia ORCID: https://orcid.org/0000-0001-6385-2866, Gauster, Martin, Raskó, Tamás, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Verlohren, Stefan ORCID: https://orcid.org/0000-0003-3507-8636, Staff, Anne Cathrine, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Pecks, Ulrich, Blois, Sandra M. ORCID: https://orcid.org/0000-0002-0434-2660, Hurst, Laurence D. and Izsvák, Zsuzsanna ORCID: https://orcid.org/0000-0002-2053-2384
[Dataset]
5 November 2025
Additional file 9 of ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia.
Anwar, Rabia, Pande, Amit ORCID: https://orcid.org/0009-0008-0826-973X, Singh, Manvendra ORCID: https://orcid.org/0000-0002-8626-5418, Huang, Zhi ORCID: https://orcid.org/0000-0002-8993-4912, Hallett, Eve ORCID: https://orcid.org/0009-0002-8268-8074, Xie, Yiran, Gellhaus, Alexandra, Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134, Nonn, Olivia ORCID: https://orcid.org/0000-0001-6385-2866, Gauster, Martin, Raskó, Tamás, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Verlohren, Stefan ORCID: https://orcid.org/0000-0003-3507-8636, Staff, Anne Cathrine, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Pecks, Ulrich, Blois, Sandra M. ORCID: https://orcid.org/0000-0002-0434-2660, Hurst, Laurence D. and Izsvák, Zsuzsanna ORCID: https://orcid.org/0000-0002-2053-2384
[Dataset]
5 November 2025
ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia.
Anwar, Rabia, Pandey, Amit ORCID: https://orcid.org/0000-0002-8886-1694, Singh, Manvendra ORCID: https://orcid.org/0000-0002-8626-5418, Huang, Zhi ORCID: https://orcid.org/0000-0002-8993-4912, Hallett, Eve ORCID: https://orcid.org/0009-0002-8268-8074, Xie, Yiran, Gellhaus, Alexandra, Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134, Nonn, Olivia ORCID: https://orcid.org/0000-0001-6385-2866, Gauster, Martin, Raskó, Tamás, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Verlohren, Stefan ORCID: https://orcid.org/0000-0003-3507-8636, Staff, Anne Cathrine, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Pecks, Ulrich, Blois, Sandra M. ORCID: https://orcid.org/0000-0002-0434-2660, Hurst, Laurence D and Izsvák, Zsuzsanna ORCID: https://orcid.org/0000-0002-2053-2384
Genome Biology 26
(1): 364.
5 November 2025
Segment anything for microscopy.
Archit, A. ORCID: https://orcid.org/0009-0002-9533-8620, Freckmann, L., Nair, S., Khalid, N. ORCID: https://orcid.org/0000-0001-9274-3757, Hilt, P., Rajashekar, V., Freitag, M. ORCID: https://orcid.org/0009-0005-0920-2535, Teuber, C. ORCID: https://orcid.org/0009-0004-3866-191X, Spitzner, M., Tapia Contreras, C., Buckley, G. ORCID: https://orcid.org/0000-0003-2763-492X, von Haaren, S., Gupta, S., Grade, M., Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Schneider, G., Dengel, A., Ahmed, S. and Pape, C. ORCID: https://orcid.org/0000-0001-6562-7187
Nature Methods 22
(3): 579-591.
March 2025
Functional landscape of ubiquitin linkages connects K29-linked ubiquitylation to epigenome integrity.
Arroyo-Gomez, J., Murray, M.J., Guérillon, C., Wang, J., Isaakova, E., Reveron-Gome, N., Koutrouli, M., Rahmanto, A.S., Mitrofanov, K., Ingham, A., Schovsbo, S., Weischenfeldt, K., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Typas, D., Völker-Albert, M., Solis, V., Jensen, L.J. ORCID: https://orcid.org/0000-0001-7885-715X, Groth, A., Mund, A., Beli, P., Shearer, R.F. and Mailand, N.
[Dataset]
17 October 2025
Functional landscape of ubiquitin linkages couples K29-linked ubiquitylation to epigenome integrity.
Arroyo-Gomez, Javier ORCID: https://orcid.org/0009-0003-7751-1853, Murray, Matthew J. ORCID: https://orcid.org/0000-0002-0379-7161, Guérillon, Claire ORCID: https://orcid.org/0000-0002-1982-6596, Wang, Juanjuan, Isaakova, Ekaterina, Reverón-Gómez, Nazaret ORCID: https://orcid.org/0000-0001-7347-781X, Koutrouli, Mikaela, Suryo Rahmanto, Aldwin, Mitrofanov, Katrine ORCID: https://orcid.org/0009-0009-2181-5552, Ingham, Andreas, Schovsbo, Sofie, Weischenfeldt, Katrine, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Typas, Dimitris, Völker-Albert, Moritz, Solis, Victor, Jensen, Lars Juhl ORCID: https://orcid.org/0000-0001-7885-715X, Groth, Anja, Mund, Andreas ORCID: https://orcid.org/0000-0002-7843-5341, Beli, Petra, Shearer, Robert F. ORCID: https://orcid.org/0000-0003-3012-8788 and Mailand, Niels ORCID: https://orcid.org/0000-0002-6623-709X
EMBO Journal 44
(23): 6944-6978.
December 2025
Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface.
Avery, E.G. ORCID: https://orcid.org/0000-0002-9094-1423, Haag, L.M., McParland, V. ORCID: https://orcid.org/0000-0003-0731-3272, Kedziora, S.M. ORCID: https://orcid.org/0000-0003-0124-2557, Zigra, G.J., Valdes, D.S. ORCID: https://orcid.org/0000-0002-1309-5147, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Nonn, O. ORCID: https://orcid.org/0000-0001-6385-2866, Karlsen, T.V., N'Diaye, G., Yarritu, A. ORCID: https://orcid.org/0000-0002-1724-0559, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Bartolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Tagiyeva, N.A. ORCID: https://orcid.org/0009-0006-7918-1220, Wimmer, M.I. ORCID: https://orcid.org/0009-0004-5793-0249, Haase, N. ORCID: https://orcid.org/0000-0003-0727-1738, Zhang, Y.D. ORCID: https://orcid.org/0009-0003-9465-2033, Wilhelm, A., Grütz, G., Tenstad, O., Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364, Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Klopfleisch, R., Kühl, A.A., Atreya, R., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Siegmund, B., Wiig, H. ORCID: https://orcid.org/0000-0002-7740-8210 and Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644
Cardiovascular Research 121
(5): 803-816.
April 2025
Augmentation of wastewater-based epidemiology with machine learning to support global health surveillance.
Aßmann, E. ORCID: https://orcid.org/0000-0002-7249-069X, Greiner, T., Richard, H. ORCID: https://orcid.org/0000-0001-7776-1340, Wade, M. ORCID: https://orcid.org/0000-0001-9824-7121, Agrawal, S., Amman, F., Böttcher, S., Lackner, S., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Mangul, S., Munteanu, V., Psomopoulos, F. ORCID: https://orcid.org/0000-0002-0222-4273, Smith, M., Trofimova, M., Ullrich, A., von Kleist, M. ORCID: https://orcid.org/0000-0001-6587-6394, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Hölzer, M. and Irrgang, C. ORCID: https://orcid.org/0000-0001-8274-1678
Nature Water 3
(7): 1124.
July 2025
Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease.
Bao, L.L. ORCID: https://orcid.org/0009-0003-3081-7062, Yu, Y.Q. ORCID: https://orcid.org/0000-0002-4847-8877, González-Acera, M. ORCID: https://orcid.org/0009-0008-9445-5650, Patankar, J.V. ORCID: https://orcid.org/0000-0002-1884-7424, Giessl, A. ORCID: https://orcid.org/0000-0002-9768-2049, Sturm, G. ORCID: https://orcid.org/0000-0001-9584-7842, Kühl, A.A. ORCID: https://orcid.org/0000-0003-2293-5387, Atreya, R. ORCID: https://orcid.org/0000-0002-8556-8433, Erkert, L., Gámez-Belmonte, R. ORCID: https://orcid.org/0000-0002-7159-8957, Krug, S.M. ORCID: https://orcid.org/0000-0002-1293-2484, Schmid, B. ORCID: https://orcid.org/0000-0002-9327-2296, Tripal, P., Chiriac, M.T., Hildner, K., Siegmund, B. ORCID: https://orcid.org/0000-0002-0055-958X, Wirtz, S. ORCID: https://orcid.org/0000-0001-6936-7431, Stürzl, M. ORCID: https://orcid.org/0000-0002-9276-2824, Mohamed Abdou, M. ORCID: https://orcid.org/0009-0002-7352-166X, Trajanoski, Z. ORCID: https://orcid.org/0000-0002-0636-7351, Neurath, M.F. ORCID: https://orcid.org/0000-0003-4344-1474, Zorzano, A. ORCID: https://orcid.org/0000-0002-1638-0306 and Becker, C. ORCID: https://orcid.org/0000-0002-1388-1041
Science Translational Medicine 17
(781): eadn8699.
January 2025
Dissecting the role of RNA-binding proteins in early herpes simplex virus 1 transcription using acute protein depletion.
Barke, N ORCID: https://orcid.org/0009-0004-5862-6628, Masser, S., Stalling, D., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Zinzen, R.P. ORCID: https://orcid.org/0000-0002-8638-5102, Schreiner, S., Bosse, J. and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
bioRxiv
: 2025.02.10.637450.
11 February 2025
Deep learning, deeper relief: pipeline toward tailored analgesia for experimental animal models.
Barleben, Luisa ORCID: https://orcid.org/0000-0002-0400-7117, Simon, Mareike ORCID: https://orcid.org/0000-0001-7213-9499, Drees, Lisa, Flohr, Franziska, Jochum, Christoph, Di Virgilio, Michela ORCID: https://orcid.org/0000-0001-5189-0793, Tacke, Frank, Bröer, Sonja, Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868 and Kolesnichenko, Marina ORCID: https://orcid.org/0000-0001-7366-9061
Frontiers in Immunology 16
: 1639881.
12 December 2025
Identification of TTLL8, POTEE, and PKMYT1 as immunogenic cancer-associated antigens and potential immunotherapy targets in ovarian cancer.
Bassoy, E.Y., Raja, R., Rubino, T.E., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Goergen, K., Magtibay, P., Butler, K., Schmitt, A., Oberg, A.L. and Curtis, M. ORCID: https://orcid.org/0000-0002-7152-6929
OncoImmunology 14
(1): 2460276.
31 January 2025
SARS-CoV-2 infection of human lung air-liquid interface cultures reveals basal cells as relevant targets.
Baumgardt, M., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Balázs, A., Löwa, A., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Hellwig, K., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Müller, M.A., Drosten, C., Mall, M.A., Hippenstiel, S., Hönzke, K. and Hocke, A.C.
Journal of Infectious Diseases 231
(5): 1210-1220.
15 May 2025
Senescence-associated lineage-aberrant plasticity evokes T-cell-mediated tumor control.
Belenki, D. ORCID: https://orcid.org/0000-0002-9004-9849, Richter-Pechanska, P. ORCID: https://orcid.org/0000-0001-6727-6317, Shao, Z., Bhattacharya, A. ORCID: https://orcid.org/0000-0003-3733-7670, Lau, A., de Freitas, J.A.N.L.F. ORCID: https://orcid.org/0000-0003-3689-765X, Kandler, G., Hick, T.P., Cai, X., Scharnagl, Eva, Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Schönlein, M., Kase, J., Pardon, K., Brzezicha, B., Thiessen, N., Bischof, O. ORCID: https://orcid.org/0000-0003-2422-6277, Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Du, J., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Chapuy, B. ORCID: https://orcid.org/0000-0002-6485-8773, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Leser, U., Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Communications 16
(1): 3079.
31 March 2025
ImmuneLENS characterizes systemic immune dysregulation in aging and cancer.
Bentham, R., Jones, T.P. ORCID: https://orcid.org/0000-0003-2748-0780, Black, J.R.M. ORCID: https://orcid.org/0000-0001-5598-7752, Martinez-Ruiz, C. ORCID: https://orcid.org/0000-0002-4817-0565, Dietzen, M. ORCID: https://orcid.org/0000-0002-6853-7563, Litovchenko, M., Thol, K. ORCID: https://orcid.org/0000-0002-4624-118X, Watkins, T.B.K., Bailey, C., Pich, O. ORCID: https://orcid.org/0000-0002-1956-1882, Zhang, Z., Van Loo, P. ORCID: https://orcid.org/0000-0003-0292-1949, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018 and McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045
Nature Genetics 57
(3): 694-705.
March 2025
The B cell dilemma: diversity or fidelity?
Berruezo-Llacuna, Maria, Kabrani, Eleni ORCID: https://orcid.org/0000-0003-0834-9912 and Di Virgilio, Michela ORCID: https://orcid.org/0000-0001-5189-0793
DNA Repair 153
: 103888.
September 2025
Identification of full-length circular RNAs linked with therapy resistance of pediatric cancers.
Bessière, Chloé, Babin, Loélia, Andraos, Elissa, Riepl, Johannes Markus, Szymansky, Annabell ORCID: https://orcid.org/0000-0003-4797-4526, Lodrini, Marco, Deubzer, Hedwig E. ORCID: https://orcid.org/0000-0002-6115-4893, Eggert, Angelika, Quivoron, Cyril, Rigaud, Charlotte, Vérgé, Véronique, Pyronnet, Stéphane, Lamant, Laurence, Meggetto, Fabienne, Gaspin, Christine and Fuchs, Steffen
medRxiv
: 2025.11.28.25340833.
4 December 2025
Structural studies suggest CCDC127 as a novel membrane contact site protein in the mitochondrial intermembrane space.
Bock-Bierbaum, Tobias ORCID: https://orcid.org/0000-0003-0843-2716, von der Malsburg, Karina, Natarajan, Ashwin Karthick ORCID: https://orcid.org/0000-0001-7897-708X, Zarges, Christine, Akkaya, Kerem Can, Aladawi, Amjad, Noll, Katja, Jungbluth, Sibylle, Schirra, Claudia, Zhu, Ying, Cremer, Nils, Bernert, Carola, Liu, Fan ORCID: https://orcid.org/0000-0002-2358-549X, Lehmann, Martin ORCID: https://orcid.org/0000-0002-8370-6353, Riemer, Jan ORCID: https://orcid.org/0000-0002-7574-8457, van der Laan, Martin ORCID: https://orcid.org/0000-0003-0789-9912 and Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414
bioRxiv
: 2025.12.11.693622.
16 December 2025
Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome.
Boehm, Volker, Wallmeroth, Damaris, Wulf, Paul O. ORCID: https://orcid.org/0009-0002-6356-2361, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Teixeira Alves, Luiz Gustavo ORCID: https://orcid.org/0000-0002-5822-4168, Reinecke, Lucie ORCID: https://orcid.org/0009-0003-7083-0923, Riedel, Maximilian ORCID: https://orcid.org/0009-0002-9817-3083, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Franitza, Marek, Becker, Kerstin, Polkovnychenko, Karina, Del Giudice, Simone ORCID: https://orcid.org/0000-0003-0194-3767, Benlasfer, Nouhad, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734 and Gehring, Niels H.
Molecular Cell 85
(18): 3524-3546.e12.
18 September 2025
Dataset: Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome. Boehm et al.
Boehm, Volker ORCID: https://orcid.org/0000-0001-7588-9842, Wallmeroth, Damaris ORCID: https://orcid.org/0000-0003-3437-4070, Wulf, Paul O. ORCID: https://orcid.org/0009-0002-6356-2361, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Teixeira Alves, Luiz Gustavo ORCID: https://orcid.org/0000-0002-5822-4168, Reinecke, Lucie ORCID: https://orcid.org/0009-0003-7083-0923, Riedel, Maximilian ORCID: https://orcid.org/0009-0002-9817-3083, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Franitza, Marek, Becker, Kerstin ORCID: https://orcid.org/0009-0009-7897-7181, Polkovnychenko, Karina ORCID: https://orcid.org/0009-0001-9468-3150, Del Giudice, Simone ORCID: https://orcid.org/0000-0003-0194-3767, Benlasfer, Nouhad, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734 and Gehring, Niels H.
[Dataset]
15 September 2025
Retinoic acid-induced 2 deficiency impairs genomic stability in breast cancer.
Boettcher, Lena, Greimeier, Sarah, Borgmann, Kerstin, Mughal, Shabbir S, Ellinger, Bernhard, Bartkowiak, Kai, Zobiak, Bernd, Failla, Antonio V, Steffen, Pascal, Claus, Ellen, Besler, Katharina, Buccitelli, Christopher ORCID: https://orcid.org/0000-0002-2637-2131, Schaaf, Violetta, Ozga, Ann-Kathrin, Parretta, Simona, Schneegans, Svenja, Mansour, Wael Y, Korbel, Jan O, Schlueter, Hartmut, Brors, Benedikt, Pantel, Klaus, Wikman, Harriet and Werner, Stefan
Breast Cancer Research 27
(1): 137.
22 July 2025
Small intestinal neuroendocrine tumors lack early genomic drivers, acquire DNA repair defects and harbor hallmarks of low REST expression.
Bolduan, F., Müller-Bötticher, N., Debnath, O. ORCID: https://orcid.org/0009-0009-2845-055X, Eichhorn, I., Giesecke, Y., Wetzel, A., Sahay, S., Zemojtel, T., Jaeger, M., Ungethuem, U., Roderburg, C., Kunze, C.A., Lehmann, A., Horst, D., Tacke, F., Eils, R., Wiedenmann, B., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X
Scientific Reports 15
(1): 17969.
23 May 2025
Proneural-mesenchymal hybrid glioblastoma cells are resistant to therapy and dependent on nuclear import.
Bourmeau, Guillaume ORCID: https://orcid.org/0000-0003-3800-4077, Anezo, Oceane, Raymond, Jeremy ORCID: https://orcid.org/0000-0002-8712-895X, Ballestín, Alberto ORCID: https://orcid.org/0000-0002-7150-9758, Pichol-Thievend, Cathy, Reveilles, Juliette ORCID: https://orcid.org/0000-0002-1307-2367, Thomas, Adrien, Wang, Lin, Miranda, Melanie, Moutaux, Eve, Liva, Stephane, Ribecco, Valentino ORCID: https://orcid.org/0000-0001-9348-4320, Besse, Laetitia, Dingli, Florent, Loew, Damarys ORCID: https://orcid.org/0000-0002-9111-8842, Vallot, Celine, Gargiulo, Gaetano ORCID: https://orcid.org/0000-0001-5414-4251, Ravi, Vidhya M. ORCID: https://orcid.org/0000-0003-0062-2099, Joseph, Kevin ORCID: https://orcid.org/0000-0001-6317-8736 and Seano, Giorgio ORCID: https://orcid.org/0000-0002-7294-302X
Neuro-Oncology 27
(11): 2876-2893.
November 2025
The establishment of cell-type specific gene regulation in the sea urchin embryo.
Brandenburg, Jonas Maurice, Trinks, Alexandra ORCID: https://orcid.org/0000-0001-9983-1506, Voijtasova, Dominika ORCID: https://orcid.org/0009-0007-4557-2490, Monaco, Anna Alessandra ORCID: https://orcid.org/0009-0000-5779-3505, Chang, William, Arsie, Roberto ORCID: https://orcid.org/0000-0002-7869-7624, Hu, Marian, Hamdoun, Amro ORCID: https://orcid.org/0000-0003-2568-048X, Jenniches, Chloe, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Blüthgen, Nils ORCID: https://orcid.org/0000-0002-0171-7447 and Garfield, David Aaron ORCID: https://orcid.org/0000-0002-8790-797X
bioRxiv
: 2025.08.12.669999.
13 August 2025
Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A.
Brierley, C.K. ORCID: https://orcid.org/0000-0002-4028-3733, Yip, B.H., Orlando, G., Wen, J., Wen, S., Goyal, H., Levine, M. ORCID: https://orcid.org/0000-0001-5156-9086, Jakobsdottir, G.M. ORCID: https://orcid.org/0000-0001-8225-6541, Tapinos, A., Cornish, A.J. ORCID: https://orcid.org/0000-0002-3966-3501, Rodriguez-Romera, A. ORCID: https://orcid.org/0000-0001-7193-9144, Rodriguez-Meira, A., Bashton, M., Hamblin, A., Clark, S.A., Hamley, J.C., Fox, O., Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, O'Sullivan, J., Murphy, L., Adamo, A., Olijnik, A.A. ORCID: https://orcid.org/0000-0002-0980-6663, Cotton, A., Hendrix, E. ORCID: https://orcid.org/0009-0006-0514-3918, Narina, S. ORCID: https://orcid.org/0000-0002-9952-1302, Pruett-Miller, S.M. ORCID: https://orcid.org/0000-0002-3793-585X, Enshaei, A. ORCID: https://orcid.org/0000-0002-7464-0743, Harrison, C. ORCID: https://orcid.org/0000-0002-3212-920X, Drummond, M., Knapper, S., Tefferi, A., Antony-Debré, I. ORCID: https://orcid.org/0000-0002-1911-146X, Davies, J. ORCID: https://orcid.org/0000-0002-4108-4357, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Thongjuea, S., Wedge, D.C. ORCID: https://orcid.org/0000-0002-7572-3196, Constantinescu, S.N., Papaemmanuil, E. ORCID: https://orcid.org/0000-0003-1709-8983, Psaila, B. ORCID: https://orcid.org/0000-0001-8198-9663, Crispino, J.D. ORCID: https://orcid.org/0000-0002-8182-8306 and Mead, A.J. ORCID: https://orcid.org/0000-0001-8522-1002
Nature Genetics 57
(6): 1478-1492.
June 2025
Generation of decellularized human brain tissue for investigating cell-matrix interactions: a proof-of-concept study.
Bueno, R.J., Fernández-Zapata, C., Salla, M. ORCID: https://orcid.org/0009-0003-8453-2935, Campo Garcia, J., Alacam, A., Klein, O., Böttcher, C. ORCID: https://orcid.org/0000-0002-6226-586X, Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Starossom, S.C. ORCID: https://orcid.org/0000-0001-7935-9910, Silva, R.V. ORCID: https://orcid.org/0000-0002-8687-2154 and Infante-Duarte, C. ORCID: https://orcid.org/0000-0003-3005-351X
Frontiers in Bioengineering and Biotechnology 13
: 1578467.
5 June 2025
Initial Test-RNA-Seq of UPF1 depletion in human colorectal adenocarcinoma cell line HCT116 via the auxin-inducible degron (AID) system.
Böhm, Volker and Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734
[Dataset]
1 September 2025
Long-read ONT-dRNA and PacBio Kinnex full-length RNA sequencing of UPF1 depletion in human colorectal adenocarcinoma cell line HCT116 via the auxin-inducible degron (AID) system.
Böhm, Volker and Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734
[Dataset]
1 September 2025
RNA-Seq of SMG1 inhibition via SMG1i in human foreskin fibroblast (HFF) and human umbilical vein endothelial cells (HUVEC).
Böhm, Volker and Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734
[Dataset]
1 September 2025
Ribo-Seq of UPF1 depletion in human colorectal adenocarcinoma cell line HCT116 via the auxin-inducible degron (AID) system.
Böhm, Volker and Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734
[Dataset]
1 September 2025
SLAM-Seq of UPF1 depletion in human colorectal adenocarcinoma cell line HCT116 via the auxin-inducible degron (AID) system.
Böhm, Volker and Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734
[Dataset]
1 September 2025
Novel non-coding FOXP3 transcript isoform associated to potential transcriptional interference in human regulatory T cells.
Cases, M., Ritter, N., Rincon-Arevalo, H., Kroh, S., Adam, A., Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Moradian, H., Gossen, M. ORCID: https://orcid.org/0000-0002-1761-4063, Dzamukova, M., Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Kressler, C., Hauser, A.E., Depledge, D.P., Polansky, J.K. and Chang, H.D.
RNA Biology 22
(1): 1-20.
2 July 2025
Extrachromosomal circular DNA promotes inflammation and hepatocellular carcinoma development.
Chan, Lap Kwan ORCID: https://orcid.org/0000-0002-9165-6982, Shan, Juanjuan ORCID: https://orcid.org/0000-0002-0640-1652, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Healy, Marc Eamonn ORCID: https://orcid.org/0000-0001-9441-1166, Leary, Peter ORCID: https://orcid.org/0000-0003-1430-6185, Parrotta, Rossella, Desboeufs, Nina ORCID: https://orcid.org/0009-0007-0883-579X, Semere, Gabriel, Wittstruck, Nadine ORCID: https://orcid.org/0009-0000-4378-3226, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Weber, Achim ORCID: https://orcid.org/0000-0003-0073-3637
Science Advances 11
(42): eadw0272.
October 2025
Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3.
Chen, K.Y., Kibayashi, T., Giguelay, A. ORCID: https://orcid.org/0000-0003-0417-1109, Hata, M., Nakajima, S., Mikami, N., Takeshima, Y., Ichiyama, K., Omiya, R., Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Hattori, K. and Sakaguchi, S.
Nature 642
(8066): 191-200.
5 June 2025
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis.
Cineus, R. ORCID: https://orcid.org/0000-0003-4393-5757, Luo, Y. ORCID: https://orcid.org/0009-0003-0401-467X, Saliutina, M., Manna, S. ORCID: https://orcid.org/0000-0003-2360-0618, Cancino, C.A., Velasco Blázquez, L., Wang, L., Bösel, D., Abdelrahman, A., Klementowicz, J.E., Scherl, A., Hainbuch, S., Bréart, B., Kwon, G., Konopka, A., Guerra, G.M., von Coburg, E. ORCID: https://orcid.org/0009-0001-8546-8854, Gerbeth, Lo., Roels, J., Heinrich, F. ORCID: https://orcid.org/0000-0001-6097-5422, Müller, N. ORCID: https://orcid.org/0000-0003-1559-7711, Durek, P. ORCID: https://orcid.org/0000-0002-6179-0670, Deigendesch, N. ORCID: https://orcid.org/0000-0002-6036-3327, Ziai, J., Hung, J., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Kühl, A.A. ORCID: https://orcid.org/0000-0003-2293-5387, Wirtz, S. ORCID: https://orcid.org/0000-0001-6936-7431, Löhning, M. ORCID: https://orcid.org/0000-0001-6382-7281, Keir, M. ORCID: https://orcid.org/0000-0002-0637-4092, Diefenbach, A. ORCID: https://orcid.org/0000-0002-9176-9530, Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Siegmund, B. ORCID: https://orcid.org/0000-0002-0055-958X, Schumann, M., Romagnani, C. ORCID: https://orcid.org/0000-0002-5167-7463, West, N.R. and Hegazy, A.N. ORCID: https://orcid.org/0000-0002-2946-8251
Nature Immunology 26
(6): 837-853.
June 2025
A vascular-associated fibroblastic cell controls pancreatic islet immunity.
Clarke, Don, Costanzo, Anne, Sharma, Siddhartha, Kain, Lisa, Moremen, Kelley W., Pettus, Jeremy, Domissy, Alain, Wu, Peng, Nguyen-Ngoc, Kim-Vy, Berti, Denise, George, Steven C., Hughes, Christopher C.W., Sander, Maike ORCID: https://orcid.org/0000-0001-5308-7785 and Teyton, Luc
Cell Reports 44
(9): 116189.
23 September 2025
A proteogenomic view of synchronous endometrioid endometrial and ovarian cancer.
Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Nielsen, A.B. ORCID: https://orcid.org/0009-0005-2855-208X, Weigert, M. ORCID: https://orcid.org/0009-0005-2855-208X, Watters, K. ORCID: https://orcid.org/0000-0002-8260-0098, Javellana, M. ORCID: https://orcid.org/0000-0002-1361-8761, Anglesio, M. ORCID: https://orcid.org/0000-0003-1639-5003, Yamada, S.D. ORCID: https://orcid.org/0000-0001-7922-4784, Lastra, R.R. ORCID: https://orcid.org/0000-0003-0691-5685, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799 and Lengyel, E. ORCID: https://orcid.org/0000-0001-8624-1507
Clinical Cancer Research 31
(11): 2230-2240.
3 June 2025
Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
19 October 2025
Spatial omics of acute myocardial infarction reveals a novel mode of immune cell infiltration.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
16 August 2025
Spatial omics of acute myocardial infarction reveals a novel mode of immune cell infiltration.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
16 August 2025
Design of combination therapeutics from protein response to drugs in ovarian cancer cells.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
19 July 2025
Extrachromosomal DNA-driven oncogene dosage heterogeneity promotes rapid adaptation to therapy in MYCN-amplified cancers.
Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
5 July 2025
Preclinical in vitro and in vivo evidence for targeting CD74 as an effective treatment strategy for cutaneous T-cell lymphomas.
Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Giordano, C., von Brünneck, A.C., Zhao, J., Makky, A., Vinh, K., Montes-Mojarro, I.A., Reisinger, F., Forchhammer, S., Witalisz-Siepracka, A., Edtmayer, S., Stoiber, D., Yin, G., Horst, D., Fischer, A., Siebert, R., Nicolay, J.P., Yin, M., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Fend, F. ORCID: https://orcid.org/0000-0002-5496-293X, Becker, J.C., Schürch, C.M., Kenner, L. ORCID: https://orcid.org/0000-0003-2184-1338, Assaf, C., Merkel, O. and Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413
British Journal of Dermatology 192
(5): 883-895.
May 2025
Patient-reported outcomes with subcutaneous immunoglobulin in secondary immunodeficiency.
Cowan, J., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Gladiator, A., Kamieniak, M. and Mustafa, S.S.
Frontiers in Immunology 16
: 1528414.
20 March 2025
Molecular machineries shaping the mitochondrial inner membrane.
Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and van der Laan, M. ORCID: https://orcid.org/0000-0003-0789-9912
Nature Reviews Molecular Cell Biology 26
(9): 706-724.
September 2025
Supplementary Material for: Compartment-specific NK cell phenotypes reveal distinct maturation and activation states in inflammatory arthritis.
Deicher, F.S., Exner, T., Claus, M., Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Rodon, L., Leonhardt, S.E., Distler, J.H.W., Watzl, C., Lorenz, H., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Hübschmann, D. and Merkt, W.
[Dataset]
26 September 2025
Compartment-specific NK cell phenotypes reveal distinct maturation and activation states in inflammatory arthritis.
Deicher, Franca Sophie, Exner, Tarik ORCID: https://orcid.org/0000-0002-3131-2133, Claus, Maren ORCID: https://orcid.org/0000-0001-8732-0645, Yousefian, Schayan ORCID: https://orcid.org/0000-0003-0902-0369, Rodon, Lea, Leonhardt, Sophie Elisabeth, Distler, Jörg H.W., Watzl, Carsten, Lorenz, Hanns-Martin, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Hübschmann, Daniel and Merkt, Wolfgang ORCID: https://orcid.org/0000-0003-3235-4906
Journal of Innate Immunity 17
(1): 522-538.
31 October 2025
Mice with a diverse human T cell receptor repertoire selected on multiple HLA class I molecules.
Dhamodaran, A. ORCID: https://orcid.org/0000-0001-7711-9593, Chen, X. ORCID: https://orcid.org/0000-0002-5614-1406, Fellmer, N., Agrawal, D., Danner, E., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803 and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Nature Communications 16
(1): 5432.
1 July 2025
Subclonal immune evasion in non-small cell lung cancer.
Dijkstra, K.K., Vendramin, R., Karagianni, D., Witsen, M., Gálvez-Cancino, F., Hill, M.S., Foster, K.A., Barbè, V., Angelova, M., Hynds, R.E., Pearce, D.R., Martínez-Ruiz, C., Black, J.R.M., Huebner, A., Pich, O., Rowan, A., Augustine, M., Puttick, C., Moore, D.A., Liu, L.L., Saghafinia, S., van de Haar, J., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Bola, S.K., Hiley, C.T., Jamal-Hanjani, M., McGranahan, N., Litchfield, K., Reading, J.L., Chain, B., Quezada, S.A., Voest, E.E. and Swanton, C.
Cancer Cell 43
(10): 1833-1849.
13 October 2025
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set.
Distler, Ute ORCID: https://orcid.org/0000-0002-8031-6384, Yoo, Han Byul, Kardell, Oliver, Hein, Dana, Sielaff, Malte, Scherer, Marian, Jozefowicz, Anna M., Leps, Christian, Gomez-Zepeda, David ORCID: https://orcid.org/0000-0002-9467-1213, von Toerne, Christine ORCID: https://orcid.org/0000-0002-4132-4322, Merl-Pham, Juliane ORCID: https://orcid.org/0000-0002-3422-4083, Barth, Teresa K., Tüshaus, Johanna ORCID: https://orcid.org/0000-0001-9206-8093, Giesbertz, Pieter ORCID: https://orcid.org/0000-0001-7461-8602, Müller, Torsten, Kliewer, Georg, Aljakouch, Karim, Helm, Barbara, Unger, Henry ORCID: https://orcid.org/0009-0001-1798-4347, Frey, Dario L. ORCID: https://orcid.org/0000-0001-9572-9686, Helm, Dominic ORCID: https://orcid.org/0000-0001-9321-2069, Schwarzmüller, Luisa ORCID: https://orcid.org/0000-0002-7151-9913, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Wudy, Susanne I. ORCID: https://orcid.org/0009-0001-6333-5233, Sinn, Ludwig Roman ORCID: https://orcid.org/0000-0003-4692-0681, Mergner, Julia ORCID: https://orcid.org/0000-0002-4332-1280, Ludwig, Christina ORCID: https://orcid.org/0000-0002-6131-7322, Imhof, Axel ORCID: https://orcid.org/0000-0003-2993-8249, Kuster, Bernhard ORCID: https://orcid.org/0000-0002-9094-1677, Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575, Krijgsveld, Jeroen, Klingmüller, Ursula, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Ralser, Markus ORCID: https://orcid.org/0000-0001-9535-7413, Mülleder, Michael ORCID: https://orcid.org/0000-0001-9792-3861, Hauck, Stefanie M. ORCID: https://orcid.org/0000-0002-1630-6827 and Tenzer, Stefan ORCID: https://orcid.org/0000-0003-3034-0017
Nature Communications 16
(1): 8774.
2 October 2025
lncRNA IGFL2-AS1 mediates NSCLC chemoresistance via YBX1-induced HSPA1A/RAP1 activation.
Dong, Hongliang, Xia, Yunxiu, Qi, Jingjing, Liu, Cuilan, Wang, Fei, Cui, Bingjie, Chen, Weiwei, Lv, Wenwen, Zhai, Nailiang, Deng, Jiong, Yu, Yong, Ning, Fangling, Schmitt, Clemens A. ORCID: https://orcid.org/0000-0002-4731-2226 and Du, Jing
Cellular and Molecular Biology Letters 30
(1): 133.
7 November 2025
Defining the mucosal ecosystem: epithelial–mesenchymal interdependence in gastrointestinal health and disease.
England, Frances J., Lin, Manqiang ORCID: https://orcid.org/0000-0003-4093-9277, Sigal, Michael ORCID: https://orcid.org/0000-0003-4772-0761 and Leedham, Simon J.
Nature Reviews Gastroenterology & Hepatology 22
(11): 741-754.
November 2025
At the crossroads of infection and malignancy: the challenge of tuberculosis in migrating populations - case report and epidemiologic analysis.
Epple, Hans-Jörg, Domaszewska, Teresa, Brünneck, Ann-Christin von, Furth, Christian, Dommerich, Steffen, Lange, Christoph, Schöning, Dinah von, Maschmeyer, Georg, Bös, Lena, Schwartz, Stefan, Schneider, Thomas and Mathas, Stephan ORCID: https://orcid.org/0000-0001-9626-1413
BMC Infectious Diseases 26
(1): 145.
26 January 2025
TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice.
Erkert, L., Ruder, B., Kabisch, M., Gamez Belmonte, R., Patankar, J.V., Gonzalez Acera, M., Schödel, L., Chiriac, M.T., Cineus, R., Gnafakis, S., Leupold, T. ORCID: https://orcid.org/0000-0002-2026-4340, Thoma, O.M. ORCID: https://orcid.org/0000-0002-1665-9753, Stolzer, I., Taut, A., Thonn, V., Zundler, S., Günther, C., Diefenbach, A., Kühl, A.A., Hegazy, A.N., Waldner, M., Basic, M. ORCID: https://orcid.org/0000-0002-1995-618X, Bleich, A., Neurath, M.F., Wirtz, S. and Becker, C. ORCID: https://orcid.org/0000-0002-1388-1041
Mucosal Immunology 18
(2): 453-466.
April 2025
Pharmacological inhibitors of the gamma-secretase enzyme complex disrupt epithelial cell function triggering colitis in mice.
Erkert, Lena, Kabisch, Melanie, Gamez-Belmonte, Reyes, Gonzalez-Acera, Miguel, Patankar, Jay V, Schödel, Lena, Hofmann, Katharina, Wagner, Yara, Plattner, Christina, Spath, Eva-Maria, Distler, Ute, Tenzer, Stefan, Neufert, Clemens, Neurath, Markus F and Becker, Christoph
Journal of Crohn's & Colitis 19
(7): jjaf096.
July 2025
Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy.
Escobar, H. ORCID: https://orcid.org/0000-0002-8128-7845, Di Francescantonio, S. ORCID: https://orcid.org/0000-0002-4815-491X, Smirnova, J., Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Müthel, S. ORCID: https://orcid.org/0000-0002-3525-8859, Marg, A. ORCID: https://orcid.org/0000-0003-3673-4244, Zhogov, A. ORCID: https://orcid.org/0009-0009-2192-0475, Krishna, S. ORCID: https://orcid.org/0009-0008-8974-0721, Metzler, E. ORCID: https://orcid.org/0000-0003-1735-6364, Petkova, M., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
Nature Communications 16
(1): 120.
2 January 2025
Fertility in patients with advanced-stage classic Hodgkin lymphoma treated with BrECADD versus eBEACOPP: a secondary analysis of the multicentre, randomised, parallel, open-label, phase 3 HD21 trial.
Ferdinandus, J., Schneider, G., Moccia, A., Greil, R., Hertzberg, M., Schaub, V., Hüttmann, A., Keil, F., Dierlamm, J., Hänel, M., Novak, U., Meissner, J., Hellmuth, J.C., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Zijlstra, J.M., Fosså, A., Viardot, A., Hertenstein, B., Martin, S., Giri, P., Kamper, P., Molin, D., Jablonski, J., Damaschin, C., Robertz, A.S., Rosenbrock, J., Fuchs, M., Borchmann, P. and Behringer, K.
Lancet Oncology 26
(8): 1081-1090.
August 2025
A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation.
Forster, P.M., Jakob, M.O., Yusuf, D., Bubeck, M., Limberger, H., Luo, Y., Thieme, P., Polici, A., Sterczyk, N., Boulekou, S., Bartel, L., Cosovanu, C., Witkowski, M., González-Acera, M., Kühl, A.A., Weidinger, C., Backofen, R., Hegazy, A.N., Patankar, J.V. and Klose, C.S.N.
Neuron 113
(9): 1333-1351.
7 May 2025
openDVP tutorial dataset.
Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534 and Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799
[Dataset]
7 July 2025
Association of an impaired GH‑IGF‑I axis with cardiac wasting in patients with advanced cancer.
Fröhlich, A.K., Porthun, J., Talha, K.M., Lena, A., Hadzibegovic, S., Wilkenshoff, U., Sonntag, F., Nikolski, A., Ramer, L.V., Zeller, T., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Anker, S.D., Haverkamp, W., von Haehling, S., Doehner, W., Rauch, U., Skurk, C., Cleland, J.G.F., Butler, J., Coats, A.J.S., Landmesser, U., Karakas, M. and Anker, M.S. ORCID: https://orcid.org/0000-0002-4406-8555
Clinical Research in Cardiology 114
(9): 1118-1132.
September 2025
PhytClust.
Ganesan, Katyayni ORCID: https://orcid.org/0009-0001-6849-0785, Kaufmann, Tom ORCID: https://orcid.org/0000-0003-4374-1338 and Schwarz, Roland ORCID: https://orcid.org/0000-0001-9155-4268
[Dataset]
11 December 2025
Penta-ALFA-tagged substrates for self-labelling tags allow signal enhancement in microscopy.
Ghosh, S. ORCID: https://orcid.org/0000-0003-1224-5008, Birke, R., Natarajan, A.K. ORCID: https://orcid.org/0000-0001-7897-708X and Broichhagen, J. ORCID: https://orcid.org/0000-0003-3084-6595
Journal of Peptide Science 31
(5): e70015.
May 2025
Altered cholesterol immunometabolism activates the macrophage NLRP3-inflammasome in lung fibrosis.
Giambelluca, Sonia, Pennitz, Peter and Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517
[Dataset]
21 November 2025
The chromatin accessibility landscape of pediatric AML.
Giguelay, A.M. ORCID: https://orcid.org/0000-0003-0417-1109 and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
Blood 145
(11): 1109-1111.
13 March 2025
Clonally expanded effector CD4(+) cytotoxic T lymphocytes are associated with severe neurological adverse events after immune checkpoint inhibitor therapy.
Giguelay, Ambre Manon ORCID: https://orcid.org/0000-0003-0417-1109, Maschmeyer, Patrick ORCID: https://orcid.org/0000-0002-1705-5302, Müller-Jensen, Leonie ORCID: https://orcid.org/0000-0002-6388-9375, Schinke, Christian, Maierhof, Smilla K., Nambiar, Natasha ORCID: https://orcid.org/0009-0004-3538-8081, Meyer, Manpreet ORCID: https://orcid.org/0009-0004-5700-8529, Huehnchen, Petra ORCID: https://orcid.org/0000-0002-6825-7270, Boehmerle, Wolfgang ORCID: https://orcid.org/0000-0001-7195-3894, Endres, Matthias ORCID: https://orcid.org/0000-0001-6520-3720, Knauss, Samuel and Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164
Journal for ImmunoTherapy of Cancer 13
(10): e012350.
30 October 2025
Comparative DNA methylation profiling of human and murine ALK‐positive B‐cell neoplasms.
Glaser, Selina ORCID: https://orcid.org/0009-0008-2923-1829, Wagener, Rabea, Harkins, Shannon K., Voena, Claudia, Bens, Susanne, Klapper, Wolfram ORCID: https://orcid.org/0000-0001-7208-4117, Laurent, Camille, Mathas, Sephan ORCID: https://orcid.org/0000-0001-9626-1413, Ren, Meiqi, Sander, Sandrine ORCID: https://orcid.org/0000-0003-4645-3366, Schnaudt‐Mastrangelo, Charlotte, Wößmann, Wilhelm ORCID: https://orcid.org/0000-0002-6315-0888, Xerri, Luc, Ammerpohl, Ole, Zelenetz, Andrew D., Louissaint, Abner, Chiarle, Roberto and Siebert, Reiner
Genes Chromosomes & Cancer 64
(7): e70060.
July 2025
Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD.
Gonzalez-Acera, Miguel, Patankar, Jay V. ORCID: https://orcid.org/0000-0002-1884-7424, Erkert, Lena, Cineus, Roodline, Gamez-Belmonte, Reyes, Leupold, Tamara, Bubeck, Marvin, Bao, Li-Li, Dinkel, Martin, Wang, Ru, Schickedanz, Laura, Limberger, Heidi, Stolzer, Iris, Gerlach, Katharina, Diemand, Leonard, Mascia, Fabrizio, Gupta, Pooja, Naschberger, Elisabeth ORCID: https://orcid.org/0000-0003-1291-622X, Koop, Kristina ORCID: https://orcid.org/0000-0002-1672-7234, Plattner, Christina, Sturm, Gregor, Weigmann, Benno ORCID: https://orcid.org/0000-0002-2398-0844, Günther, Claudia ORCID: https://orcid.org/0000-0001-8360-3525, Wirtz, Stefan, Stürzl, Michael ORCID: https://orcid.org/0000-0002-9276-2824, Hildner, Kai, Kühl, Anja A., Siegmund, Britta ORCID: https://orcid.org/0000-0002-0055-958X, Gießl, Andreas, Atreya, Raja ORCID: https://orcid.org/0000-0002-8556-8433, Hegazy, Ahmed N., Trajanoski, Zlatko, Neurath, Markus F. ORCID: https://orcid.org/0000-0003-4344-1474 and Becker, Christoph ORCID: https://orcid.org/0000-0002-1388-1041
Gut 74
(10): 1602-1615.
8 September 2025
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy.
Grunewald, L. ORCID: https://orcid.org/0000-0002-7175-7380, Andersch, L., Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Schwiebert, S., Klaus, A., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Straka, T., Lodrini, M., Wicha, S.G., Fuchs, S., Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Westermann, F., Vitali, A., Caramel, C., Büchel, G., Eilers, M., Astrahantseff, K., Eggert, A., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Anders, K. ORCID: https://orcid.org/0000-0002-0429-200X and Künkele, A.
Pharmacological Research 212
: 107608.
February 2025
A kinetics-based model of hematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells - data repository.
Grünschläger, Florian ORCID: https://orcid.org/0000-0003-0021-6912, Rodriguez-Correa, Esther, Nizharadze, Tamar, Sedlmeier, Anastasia ORCID: https://orcid.org/0009-0002-0418-2131, Hübschmann, Daniel ORCID: https://orcid.org/0000-0002-6041-7049 and Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051
[Dataset]
January 2025
Generation of a human induced pluripotent stem cell line (BIHi292-A) from PBMCs of a female patient diagnosed with Nasu-Hakola disease (NHD)/polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) carrying a novel heterozygous mutation in the TREM2 gene.
Göttert, R. ORCID: https://orcid.org/0000-0003-4756-7381, Vallone, V.F., Stachelscheid, H., Metzger, J.J. ORCID: https://orcid.org/0000-0001-6813-4425, Caedo, C.C., Buthut, M., Prüss, H., Endres, M., Schilling, S. and Gertz, K.
Stem Cell Research 83
: 103660.
March 2025
Hashed data from three immortalized fibroblastic reticular cells (iFRCs).
Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Dietrich, Sascha and Hübschmann, Daniel
[Dataset]
2 December 2025
Resolving intra-tumor heterogeneity and clonal evolution of core-binding factor acute myeloid leukemia patients with single-cell resolution.
Hablesreiter, Raphael, Strzelecka, Paulina M. ORCID: https://orcid.org/0000-0003-0226-6788, Kopp, Klara, Estrada, Natalia, Dolnik, Anna, Tilgner, Marlon, Fustero-Torre, Coral, Thol, Felicitas, Heidel, Florian H., Heuser, Michael, Haghverdi, Laleh ORCID: https://orcid.org/0000-0001-9280-9170, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Christen, Friederike and Damm, Frederik
Experimental Hematology & Oncology 14
(1): 127.
28 October 2025
The deubiquitinase OTUD7B ameliorates central nervous system autoimmunity by inhibiting degradation of glial fibrillary acidic protein and astrocyte hyperinflammation.
Harit, K., Yi, W., Jeron, A., Schmidt, J., Beckervordersandfort-Bonk, R., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Plumbon, I., Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Deckert, M., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Wang, X., Nishanth, G. and Schlüter, D.
[Dataset]
1 December 2025
Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation.
Harit, Kunjan, Yi, Wenjing, Jeron, Andreas, Schmidt, Jakob, Beckervordersandforth, Ruth ORCID: https://orcid.org/0000-0002-3617-7567, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Manukyan, Artür ORCID: https://orcid.org/0000-0002-0441-9517, Deckert, Martina, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, Janine ORCID: https://orcid.org/0000-0003-4372-1521, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Wang, Xu ORCID: https://orcid.org/0000-0001-8428-9339, Nishanth, Gopala ORCID: https://orcid.org/0000-0002-7280-5663 and Schlüter, Dirk ORCID: https://orcid.org/0000-0003-1478-3328
Nature Communications 16
(1): 9279.
20 October 2025
Morphogenetic ovarian modules for oocyte production from germline stem cells.
Hart, Neta, Kroll, Johanna B. ORCID: https://orcid.org/0000-0003-4652-3598, Kumar, Vineet, Czukiewska, Sylwia M. ORCID: https://orcid.org/0000-0001-9151-9008, Bogoch, Yoel, Guler, Noga ORCID: https://orcid.org/0009-0004-8560-1995, Levy, Karine ORCID: https://orcid.org/0000-0003-0290-062X, Chuva de Sousa Lopes, Susana M., Junker, Jan Philipp ORCID: https://orcid.org/0000-0002-2826-8290 and Elkouby, Yaniv M. ORCID: https://orcid.org/0000-0002-9043-4106
Research Square
: rs-7325126/v1.
28 October 2025
Gonadal sex and temperature independently influence germ cell differentiation and meiotic progression in Trachemys scripta.
Hatkevich, T., Tezak, B.M., Acemel, R.D. ORCID: https://orcid.org/0000-0003-4120-0140, Yee Chung, V.W., Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X and Capel, B. ORCID: https://orcid.org/0000-0002-6587-0969
Proceedings of the National Academy of Sciences of the United States of America 122
(1): e2413191121.
7 January 2025
IL-36 signaling as a drug target in Crohn's disease patients with IL36RN mutations.
Hecker, J. ORCID: https://orcid.org/0000-0002-4118-3961, Plattner, C. ORCID: https://orcid.org/0000-0002-3217-3278, Cancino, C.A., Löscher, B.S., Saurenbach, J., Letizia, M., Rieder, D., Freise, I., Koop, K., Neufert, C., Kunkel, D., Al Khatim, Z., Schaafs, L.A., Schütz, A. ORCID: https://orcid.org/0000-0002-0606-2574, Becker, C., Atreya, R., Trajanoski, Z. ORCID: https://orcid.org/0000-0002-0636-7351, Franke, A., Sonnenberg, E., Hegazy, A.N., Siegmund, B. ORCID: https://orcid.org/0000-0002-0055-958X and Weidinger, C. ORCID: https://orcid.org/0000-0002-9948-0088
EMBO Molecular Medicine 17
(7): 1539-1555.
11 July 2025
Insights, opportunities, and challenges provided by large cell atlases.
Hemberg, Martin, Marini, Federico, Ghazanfar, Shila, Al Ajami, Ahmad, Abassi, Najla, Anchang, Benedict, Benayoun, Bérénice A., Cao, Yue, Chen, Ken, Cuesta-Astroz, Yesid, DeBruine, Zachary, Dendrou, Calliope A., De Vlaminck, Iwijn, Imkeller, Katharina, Korsunsky, Ilya, Lederer, Alex R., Li, Jessica Jingyi, Meysman, Pieter, Miller, Clint L, Mullan, Kerry A., Ohler, Uwe ORCID: https://orcid.org/0000-0002-0881-3116, Panwar, Pratibha, Patikas, Nikolaos, Schuck, Jonas, Siu, Jacqueline H.Y., Triche, Timothy J., Tsankov, Alex, van der Laan, Sander W., Yajima, Masanao, Yang, Jean, Zanini, Fabio and Jelic, Ivana
Genome Biology 26
(1): 358.
20 October 2025
Genetic alterations of SENP6 disrupt DNA repair and proteostasis conferring sensitivity to proteasome inhibition in multiple myeloma.
Herzberg, F., Korenkov, M. ORCID: https://orcid.org/0000-0002-2988-8483, Isaakidis, K., Zang, C., Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Müller, S., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Demel, U.M. ORCID: https://orcid.org/0000-0002-6480-4185
[Dataset]
8 December 2025
Extrusion of BMP2+ surface colonocytes promotes stromal remodeling and tissue regeneration.
Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Liu, L., Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, van den Heuvel, J., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Müllerke, S., Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725, de Jonge, H. ORCID: https://orcid.org/0000-0003-2777-4084, Gherardi, E. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 16
(1): 4131.
3 May 2025
Serially quantifying TERT rearrangement breakpoints in circulating tumor DNA enables minimal residual disease monitoring in patients with neuroblastoma.
Hollander, J.F. ORCID: https://orcid.org/0009-0001-2907-2206, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Wünschel, J. ORCID: https://orcid.org/0009-0007-5658-7532, Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997, Rosswog, C. ORCID: https://orcid.org/0000-0002-8855-6198, Thorwarth, A. ORCID: https://orcid.org/0000-0001-6290-9963, Thole-Kliesch, T.M. ORCID: https://orcid.org/0000-0003-2714-6221, Chamorro Gonzalez, R. ORCID: https://orcid.org/0000-0002-5653-7259, Hundsdörfer, P. ORCID: https://orcid.org/0009-0007-1158-5170, Hauptmann, K. ORCID: https://orcid.org/0000-0003-0590-3674, Schmelz, K. ORCID: https://orcid.org/0009-0009-6954-9927, Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Rogasch, J.M.M. ORCID: https://orcid.org/0000-0002-0817-6532, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Eckert, C. ORCID: https://orcid.org/0000-0003-1039-2872, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Lodrini, M. ORCID: https://orcid.org/0000-0003-4434-529X and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Cancer Research Communications 5
(1): 167-177.
28 January 2025
Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4(+) T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease.
Horn, V., Cancino, C.A., Steinheuer, L.M., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Fritz, K., Nguyen, A.L., Juhran, K.S., Plattner, C., Bösel, D., Oldenburg, L., Burns, M., Schulz, A.R., Saliutina, M., Mantzivi, E., Lissner, D., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Mashreghi, M.F., Zundler, S., Sonnenberg, E., Schumann, M., Haag, L.M., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Flatz, L., Trjanoski, Z., D'Haens, G., Weidinger, C., Mei, H.E., Siegmund, B., Thurley, K. and Hegazy, A.N.
Gastroenterology 168
(2): 327-343.
February 2025
Spatial proteomics in translational and clinical research.
Horvath, P. ORCID: https://orcid.org/0000-0002-4492-1798 and Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081
Molecular Systems Biology 21
(6): 526-530.
June 2025
GeneSys: generative modeling of developmental system.
Hsu, Che-Wei ORCID: https://orcid.org/0000-0003-3709-9748, Chen, Chia-Yu ORCID: https://orcid.org/0000-0003-1765-7132, Nolan, Trevor M. ORCID: https://orcid.org/0000-0003-1362-2557, Benfey, Philip N. ORCID: https://orcid.org/0000-0001-5302-758X and Ohler, Uwe ORCID: https://orcid.org/0000-0002-0881-3116
bioRxiv
: 2025.08.20.671385.
25 August 2025
T cell receptors specific for an imatinib-induced mutation in BCR-ABL for adoptive T cell therapy.
Hsu, M.T. ORCID: https://orcid.org/0000-0002-5862-4305, Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128 and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Frontiers in Immunology 16
: 1518691.
27 January 2025
Practice variations in indication, timing and outcome of Multiple Myeloma patients undergoing surgery for vertebral lesions – results from the European M2Spine study group.
Hubertus, Vanessa, Viezens, Lennart, Stangenberg, Martin, Früh, Anton M., Meyer, Hanno S., Liang, Raimunde, Kramer, Andreas, Orban, Christoph, Kerschbaumer, Johannes, Kunze, Beate, Telera, Stefano, Miller, Hannah, Entenmann, Christian J., von Bronewski, Emily J., Buhre, Charlotte, Leonhardt, Leon-Gordian, Willenbacher, Wolfgang, Kvitsaridze, Irma, Laue, Dominik, Pumberger, Matthias, Keller, Theresa, Acker, Güliz, Krönke, Jan, Blau, Igor-Wolfgang, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Ringel, Florian, Thomé, Claudius, Meyer, Bernhard, Vajkoczy, Peter, Dreimann, Marc and Onken, Julia Sophie
Journal of Neuro-Oncology 174
(3): 765-777.
September 2025
Rapid glycoprotein evolution enables variant interactions in herpes simplex virus type 1.
Höfler, Thomas ORCID: https://orcid.org/0000-0001-7486-5582, Zeitlow, Michaela, Kim, Ji Y., Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806 and Trimpert, Jakob ORCID: https://orcid.org/0000-0003-1616-0810
Virus Evolution 11
(1): veaf072.
6 October 2025
Extensive folding variability between homologous chromosomes in mammalian cells.
Irastorza-Azcarate, I. ORCID: https://orcid.org/0000-0001-5245-2322, Kukalev, A. ORCID: https://orcid.org/0000-0001-5847-3773, Kempfer, R. ORCID: https://orcid.org/0000-0002-8588-8576, Thieme, C.J. ORCID: https://orcid.org/0000-0002-1566-0971, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Markowski, J. ORCID: https://orcid.org/0000-0002-0573-7832, Loof, G. ORCID: https://orcid.org/0000-0003-3967-6115, Sparks, T.M. ORCID: https://orcid.org/0000-0002-9455-8309, Brookes, E. ORCID: https://orcid.org/0000-0003-2175-4349, Natarajan, K.N. ORCID: https://orcid.org/0000-0002-9264-1280, Sauer, S., Fisher, A.G. ORCID: https://orcid.org/0000-0003-3010-3644, Nicodemi, M. ORCID: https://orcid.org/0000-0002-8416-6416, Ren, B., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Pombo, A. ORCID: https://orcid.org/0000-0002-7493-6288
Molecular Systems Biology 21
(7): 735-775.
2 July 2025
Enteric nervous system-derived VIP restrains differentiation of LGR(5)(+) stem cells toward the secretory lineage impeding type 2 immune programs.
Jakob, Manuel O. ORCID: https://orcid.org/0000-0003-3638-3114, Sterczyk, Nele, Boulekou, Sotiria, Forster, Patrycja M., Barleben, Luisa ORCID: https://orcid.org/0000-0002-0400-7117, Alzain, Nadra, Jarick, Katja J. ORCID: https://orcid.org/0000-0001-5162-7266, Pirzgalska, Roksana M., Raposo, Bruno ORCID: https://orcid.org/0000-0003-4734-7207, Hansson, Karl, Nyström, Elisabeth E.L., Gondrand, Aurelia ORCID: https://orcid.org/0009-0004-9989-4899, González-Acera, Miguel, Leclère, Pierre S. ORCID: https://orcid.org/0000-0002-1794-9461, Lapson, Marlen S., Poggenseier, Sarah ORCID: https://orcid.org/0009-0001-5343-9987, Deshpande, Divija ORCID: https://orcid.org/0000-0001-9166-2509, Velleman, Laura ORCID: https://orcid.org/0009-0002-7347-8067, Breiderhoff, Tilman ORCID: https://orcid.org/0000-0002-1676-7498, Brunkhorst, Max Felix, Schüle, Anton M. ORCID: https://orcid.org/0009-0003-3094-9778, Guerra, Gabriela M., Durek, Pawel ORCID: https://orcid.org/0000-0002-6179-0670, Mashreghi, Mir-Farzin ORCID: https://orcid.org/0000-0002-8015-6907, Kühl, Anja A. ORCID: https://orcid.org/0000-0003-2293-5387, Chu, Coco, Schneider, Christoph ORCID: https://orcid.org/0000-0002-0452-2960, Weidinger, Carl ORCID: https://orcid.org/0000-0002-9948-0088, Siegmund, Britta ORCID: https://orcid.org/0000-0002-0055-958X, Nordmann, Thierry M., Voehringer, David ORCID: https://orcid.org/0000-0001-6650-0639, Patankar, Jay V., Becker, Christoph ORCID: https://orcid.org/0000-0002-1388-1041, Birchenough, George M.H., Veiga-Fernandes, Henrique ORCID: https://orcid.org/0000-0001-6216-1836, Ronchi, Francesca, Kolesnichenko, Marina ORCID: https://orcid.org/0000-0001-7366-9061, Diefenbach, Andreas ORCID: https://orcid.org/0000-0002-9176-9530 and Klose, Christoph S.N. ORCID: https://orcid.org/0000-0001-8803-2979
Nature Immunology 26
(12): 2227-2243.
December 2025
Leveraging large language models for data analysis automation.
Jansen, J.A., Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Al Khoury, N. and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
PLoS ONE 20
(2): e0317084.
21 February 2025
Prior chemotherapy deteriorates T-cell quality for CAR T-cell therapy in B-cell non-Hodgkin's lymphoma.
Junkuhn, C., Schiele, P., Walter, A.L., Hamm, F., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Busch, D., Stroux, A., Frick, M., Penack, O., Damm, F., Polansky, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Künkele, A., Frentsch, M. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Journal for ImmunoTherapy of Cancer 13
(4): e010709.
April 2025
Familial Alzheimer disease mutation identifies novel role of SORLA in release of neurotrophic exosomes.
Juul-Madsen, K. ORCID: https://orcid.org/0000-0002-5309-5221, Rudolph, I.M. ORCID: https://orcid.org/0000-0002-3903-0755, Gomes, J.P., Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887, Ovesen, P.L. ORCID: https://orcid.org/0000-0001-8801-4711, Gorniak-Walas, M. ORCID: https://orcid.org/0000-0003-1236-8622, Kokoli, M. ORCID: https://orcid.org/0000-0002-1411-3730, Telugu, N.S. ORCID: https://orcid.org/0000-0003-4509-7056, Sivertsen, M.V.T., Sutherland, D., Palmfeldt, J.S, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Andersen, O. ORCID: https://orcid.org/0000-0003-4226-3354, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921
bioRxiv
: 2025.04.22.649924.
25 April 2025
Familial Alzheimer's disease mutation identifies novel role of SORLA in release of neurotrophic exosomes.
Juul-Madsen, Kristian ORCID: https://orcid.org/0000-0002-5309-5221, Rudolph, Ina-Maria ORCID: https://orcid.org/0000-0002-3903-0755, Gomes, Jemila P. ORCID: https://orcid.org/0009-0004-1027-8599, Meyer, Katrina ORCID: https://orcid.org/0000-0002-8244-6887, Ovesen, Peter L. ORCID: https://orcid.org/0000-0001-8801-4711, Gorniak-Walas, Malgorzata ORCID: https://orcid.org/0000-0003-1236-8622, Kokoli, Marianna ORCID: https://orcid.org/0000-0002-1411-3730, Telugu, Narasimha S. ORCID: https://orcid.org/0000-0003-4509-7056, vonTangen Sivertsen, Malthe, Febbraro, Fabia ORCID: https://orcid.org/0000-0001-8336-2776, Sutherland, Duncan S. ORCID: https://orcid.org/0000-0002-5045-9915, Palmfeldt, Johan ORCID: https://orcid.org/0000-0001-5585-639X, Diecke, Sebastian ORCID: https://orcid.org/0000-0002-5219-5992, Andersen, Olav M. ORCID: https://orcid.org/0000-0003-4226-3354, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751 and Willnow, Thomas E. ORCID: https://orcid.org/0000-0001-9515-7921
Alzheimer's & Dementia 21
(9): e70591.
10 September 2025
RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses.
Kabrani, E. ORCID: https://orcid.org/0000-0003-0834-9912, Rahjouei, A. ORCID: https://orcid.org/0000-0003-3973-6333, Berruezo-Llacuna, M., Ebeling, S. ORCID: https://orcid.org/0009-0005-4954-0731, Saha, T., Altwasser, R. ORCID: https://orcid.org/0009-0002-6216-6068, Delgado-Benito, V. ORCID: https://orcid.org/0000-0002-0077-1935, Pavri, R. ORCID: https://orcid.org/0000-0002-6191-6333 and Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793
Nature Communications 16
(1): 777.
17 January 2025
Functional liver genomics identifies hepatokines promoting wasting in cancer cachexia.
Kaltenecker, Doris, Fisker Schmidt, Søren, Weber, Peter, Loft, Anne, Morigny, Pauline, Machado, Juliano, Geppert, Julia, Saul, Kerstin Beate, Benedikt, Pia, Molocea, Claudia-Eveline, Scott, Rachel, Haase, Kerstin ORCID: https://orcid.org/0000-0002-0944-5618, Martignoni, Marc E., Alfaro, Ana Jimena, Chow, Kan Kau, Simoes, Estefania, Pinhata Otoch, José, Lima, Joanna D.C.C., Swanton, Charles, Spielmann, Nadine, Hrabé de Angelis, Martin, Elsner, Markus, Ertürk, Ali, Dyar, Kenneth A., Rohm, Maria, Prokopchuk, Olga, Jamal-Hanjani, Mariam, Seelaender, Marilia, Backs, Johannes ORCID: https://orcid.org/0000-0002-2322-2699, Herzig, Stephan and Berriel Diaz, Mauricio
Cell 188
(17): 4549-4566.
21 August 2025
Multicenter longitudinal quality assessment of MS-based proteomics in plasma and serum.
Kardell, O. ORCID: https://orcid.org/0000-0002-6703-7997, Gronauer, T., von Toerne, C., Merl-Pham, J., König, A.C., Barth, T.K., Mergner, J., Ludwig, C. ORCID: https://orcid.org/0000-0002-6131-7322, Tüshaus, J., Giesbertz, P., Breimann, S. ORCID: https://orcid.org/0000-0002-0305-3373, Schweizer, L., Müller, T., Kliewer, G., Distler, U. ORCID: https://orcid.org/0000-0002-8031-6384, Gomez-Zepeda, D. ORCID: https://orcid.org/0000-0002-9467-1213, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Qin, D. ORCID: https://orcid.org/0000-0002-9730-4072, Teupser, D., Cox, J. ORCID: https://orcid.org/0000-0001-8597-205X, Imhof, A. ORCID: https://orcid.org/0000-0003-2993-8249, Küster, B. ORCID: https://orcid.org/0000-0002-9094-1677, Lichtenthaler, S.F., Krijgsveld, J., Tenzer, S. ORCID: https://orcid.org/0000-0003-3034-0017, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081 and Hauck, S.M. ORCID: https://orcid.org/0000-0002-1630-6827
Journal of Proteome Research 24
(3): 1017-1029.
7 March 2025
Comparing functional and genomic-based precision medicine in blood cancer patients.
Kazianka, L., Pichler, A., Agreiter, C., Rohrbeck, J., Kornauth, C., Porpaczy, E., Sillaber, C., Sperr, W.R., Gleixner, K.V., Hauswirth, A., Jäger, U., Valent, P., Jonak, C., Porkert, S., Exner, R., Willenbacher, W., Wolf, D., Neumeister, P., Prochazka, K., Deutsch, A., Greil, R., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Ristl, R., Mayerhoefer, M., Simonitsch-Klupp, I., Pemovska, T. ORCID: https://orcid.org/0000-0003-2951-4905 and Staber, P.B.
HemaSphere 9
(4): e70129.
April 2025
Butyrate rescues cardiac metabolic dysfunction in hypertensive heart failure with preserved ejection fraction.
Kedziora, Sarah M. ORCID: https://orcid.org/0000-0003-0124-2557, Geisberger, Sabrina Y. ORCID: https://orcid.org/0000-0001-6477-1312, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Frolova, Alina ORCID: https://orcid.org/0000-0001-5469-7366, Uhrbach, Alisa, Kräker, Kristin ORCID: https://orcid.org/0000-0002-4032-5382, Tagiyeva, Nurana ORCID: https://orcid.org/0009-0006-7918-1220, Kelm, Marcus, Berndt, Nikolaus, Zhang, Yiming D. ORCID: https://orcid.org/0009-0003-9465-2033, Mastrobuoni, Guido ORCID: https://orcid.org/0000-0003-4509-1295, Escrihuela-Branz, Raquel, Bartolomaeus, Theda U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Pixner, Lorenz, Fahjen, Pauline ORCID: https://orcid.org/0000-0002-5015-0643, Kaufhold, Gelsomina N. ORCID: https://orcid.org/0009-0009-0868-3284, Parakkat, Pragati ORCID: https://orcid.org/0000-0003-2691-791X, Chitroceanu, Alexandra Maria, Tschöpe, Carsten, Edelmann, Frank, Schiattarella, Gabriele G. ORCID: https://orcid.org/0000-0002-7582-7171, Forslund, Sofia K. ORCID: https://orcid.org/0000-0003-4285-6993, Wilck, Nicola ORCID: https://orcid.org/0000-0003-3189-5364, Gotthardt, Michael ORCID: https://orcid.org/0000-0003-1788-3172, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Sawamiphak, Suphansa ORCID: https://orcid.org/0000-0003-2298-3565, Müller, Dominik N. ORCID: https://orcid.org/0000-0003-3650-5644, Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299 and Haase, Nadine ORCID: https://orcid.org/0000-0003-0727-1738
bioRxiv
: 2025.11.28.690152.
30 November 2025
Structural and transduction patterns of human-specific polymorphic SVA insertions.
Kirby, Ashley E., Loftus, Mark, Golba, Emily C. and Konkel, Miriam K.
Mobile DNA 16
(1): 42.
6 November 2025
Implementation and outcome of personalized treatment strategies in advanced genitourinary cancers.
Klostermann, A., Debertshäuser, T., Benary, M. ORCID: https://orcid.org/0000-0002-3067-2030, Biernath, N., Erber, B., Tahbaz, R., Möbs, M., Joosten, M., Schmitt, W.D., Kim, T., Jelas, I., Chai, L., Jegodka, Y., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Ochsenreither, S., De Santis, M., Schlomm, T., Keilholz, U., Knödler, M. and Rieke, D.T.
ESMO Open 10
(7): 105497.
July 2025
Simplified preanalytical laboratory procedures for therapeutic drug monitoring (TDM) in patients treated with high-dose methotrexate (HD-MTX) and glucarpidase.
Knörnschild, F.L. ORCID: https://orcid.org/0009-0004-6437-9774, Liebig, S. ORCID: https://orcid.org/0000-0002-5494-8476, Kießling, P., Prpic, M. ORCID: https://orcid.org/0009-0006-3730-5037, Kim, T., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Kappert, K. ORCID: https://orcid.org/0000-0001-6976-0428, Schwartz, S. ORCID: https://orcid.org/0000-0001-8833-5793 and Jahic, A. ORCID: https://orcid.org/0000-0001-8318-0147
Clinical Chemistry and Laboratory Medicine 63
(1): e11-e15.
2025
Exovelo: cell states velocity estimation without parameter fitting.
Kolb, Yiftach Josef ORCID: https://orcid.org/0009-0002-3752-3326 and Haghverdi, Laleh ORCID: https://orcid.org/0000-0001-9280-9170
bioRxiv
: 2025.07.02.662720v2.
12 September 2025
Contextualizing models: deriving a kinetic model of cancer metabolism including growth via stoichiometric reduction.
Komkova, Daria, Simon, Mareike ORCID: https://orcid.org/0000-0001-7213-9499, Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868 and Steuer, Ralf ORCID: https://orcid.org/0000-0003-2217-1655
bioRxiv
: 2025.08.29.672875.
3 September 2025
Chronic inflammatory demyelinating polyneuropathy (CIDP) after cilta-cel therapy.
Korenkov, M. ORCID: https://orcid.org/0000-0002-2988-8483, Liebaert, J. ORCID: https://orcid.org/0000-0002-2988-8483, Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Schwartz, S. ORCID: https://orcid.org/0000-0001-8833-5793, Demel, U.M. ORCID: https://orcid.org/0000-0002-6480-4185, Braune, J. ORCID: https://orcid.org/0000-0003-2026-2641, Odabasi, M.C., Herzberg, L., Böckle, D., Görür, N.C. ORCID: https://orcid.org/0000-0001-7857-2461, V. Landenberg-Roberg, V., Bohl, S., Tregel, E., Hennig, S., Franke, C. ORCID: https://orcid.org/0000-0002-5609-2472, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Krönke, J. and Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947
Blood Cancer Journal 15
(1): 168.
20 October 2025
Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons.
Kroll, Jana ORCID: https://orcid.org/0000-0003-4243-4088, Kravčenko, Uljana ORCID: https://orcid.org/0009-0004-7176-8444, Sadeghi, Mohsen ORCID: https://orcid.org/0000-0002-7698-5630, Diebolder, Christoph A. ORCID: https://orcid.org/0000-0001-7694-7362, Ivanov, Lia, Lubas, Małgorzata, Sprink, Thiemo ORCID: https://orcid.org/0000-0002-0760-6828, Schacherl, Magdalena ORCID: https://orcid.org/0000-0002-5478-2509, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Rosenmund, Christian ORCID: https://orcid.org/0000-0002-3905-2444
Nature Communications 16
(1): 11131.
15 December 2025
A phase I study of MAGE-A1-targeted T1367 T-cell receptor-based cell therapy in patients with advanced multiple myeloma.
Krüger, J., Obenaus, M. ORCID: https://orcid.org/0000-0002-5090-9162, Blau, I.W., Hoser, D., Vaegler, M. ORCID: https://orcid.org/0009-0005-3852-4525, Rauschenbach, H., Anagnostopoulos, I., Jöhrens, K., Scheuplein, V., Kieback, E. ORCID: https://orcid.org/0000-0003-3831-2846, Böhme, J., Von Brünneck, A.C., Krönke, J., Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947, Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Nogai, A.
Haematologica 110
(1): 244-250.
January 2025
Cell type-specific purifying selection of synonymous mitochondrial DNA variation.
Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Maschmeyer, Patrick ORCID: https://orcid.org/0000-0002-1705-5302, Yin, Yajie ORCID: https://orcid.org/0000-0002-2220-005X, Gutierrez, Jacob C., Dhindsa, Ryan S. ORCID: https://orcid.org/0000-0002-8965-0813, Gribling-Burrer, Anne-Sophie, Zielinski, Sebastian ORCID: https://orcid.org/0000-0001-5070-1209, Hsieh, Yu-Hsin ORCID: https://orcid.org/0000-0003-3037-8728, Nitsch, Lena ORCID: https://orcid.org/0000-0003-0775-1969, Dimitrova, Veronika ORCID: https://orcid.org/0009-0007-6915-7136, Nalbant, Benan, Buquicchio, Frank A. ORCID: https://orcid.org/0000-0002-9910-4947, Abay, Tsion ORCID: https://orcid.org/0009-0009-0024-2732, Stickels, Robert R., Ulirsch, Jacob C., Yan, Patrick, Wang, Fangyi ORCID: https://orcid.org/0009-0000-8310-3088, Miao, Zhuang, Sandor, Katalin ORCID: https://orcid.org/0000-0003-2892-4865, Daniel, Bence, Liu, Vincent, Mendez, Paul L. ORCID: https://orcid.org/0000-0003-2025-7981, Knaus, Petra, Meyer, Manpreet ORCID: https://orcid.org/0009-0004-5700-8529, Greenleaf, William J. ORCID: https://orcid.org/0000-0003-1409-3095, Kundaje, Anshul ORCID: https://orcid.org/0000-0003-3084-2287, Smyth, Redmond P. ORCID: https://orcid.org/0000-0002-1580-0671, Munschauer, Mathias ORCID: https://orcid.org/0000-0001-6143-4548, Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164 and Satpathy, Ansuman T. ORCID: https://orcid.org/0000-0002-5167-537X
Proceedings of the National Academy of Sciences of the United States of America 122
(30): e2505704122.
29 July 2025
High incidence and impact of suspected exocrine pancreatic insufficiency in patients post-hematopoietic stem cell transplantation: a single-center prospective observational study.
Launspach, M. ORCID: https://orcid.org/0000-0001-5337-5605, Mindermann, A., Schulz, J., Alasfar, L., Cyrull, S., Zirngibl, F., Oevermann, L., Künkele, A., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, von Bernuth, H., Pruß, A., Lang, P., Bufler, P., Eggert, A., von Stackelberg, A. and Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201
United European Gastroenterology Journal 13
(2): 257-267.
March 2025
Personalized CRISPR knock-in cytokine gene therapy to remodel the tumor microenvironment and enhance CAR T cell therapy in solid tumors.
Launspach, Michael ORCID: https://orcid.org/0000-0001-5337-5605, Macos, Julia ORCID: https://orcid.org/0009-0008-9196-3975, Afzal, Shoaib ORCID: https://orcid.org/0009-0009-5490-6098, Hohmann, Janik ORCID: https://orcid.org/0009-0001-5374-1350, Appis, Marc L. ORCID: https://orcid.org/0000-0002-0155-1918, Pilgram, Maximilian ORCID: https://orcid.org/0009-0002-3423-5249, Beez, Stefanie, Ohlendorf, Emily, van der Ven, Casper F.T. ORCID: https://orcid.org/0000-0001-7947-6105, Lachiheb, Chahrazad, Töws, Karin, Andersch, Lena, Jens, Marvin ORCID: https://orcid.org/0000-0002-6660-8743, Zirngibl, Felix ORCID: https://orcid.org/0000-0003-1764-4841, Kath, Jonas ORCID: https://orcid.org/0000-0001-7721-7978, Stecklum, Maria ORCID: https://orcid.org/0009-0001-7951-5730, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Anders, Kathleen ORCID: https://orcid.org/0000-0002-0429-200X, Wagner, Dimitrios L. ORCID: https://orcid.org/0000-0002-2189-3579, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Kühn, Ralf ORCID: https://orcid.org/0000-0003-1694-9803, Eggert, Angelika and Künkele, Annette ORCID: https://orcid.org/0000-0002-8406-5412
Nature Communications 16
(1): 10987.
9 December 2025
SARS-CoV-2 neutralization and protection of hamsters via nasal administration of a humanized neutralizing antibody.
Lebedin, Mikhail ORCID: https://orcid.org/0000-0002-3877-7195, Petrovsky, Nikolai ORCID: https://orcid.org/0000-0002-1580-5245, Tabynov, Kairat, Tabynov, Kaissar and Lebedin, Yuri
Antiviral Research 241
: 106235.
September 2025
Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration.
Lekkos, Konstantinos, Hu, Zhilian, Nguyen, Phong D., Honkoop, Hessel, Sengul, Esra, Alonaizan, Rita, Koth, Jana, Ying, Jun, Lemieux, Madeleine E., Kenward, Alisha, Keeley, Sean, Spanjaard, Bastiaan ORCID: https://orcid.org/0000-0003-1309-8839, Kennedy, Brett W.C., Sun, Xin, Banecki, Katherine, Potts, Helen G., Ruggiero, Gennaro, Montgomery, James, Panáková, Daniela ORCID: https://orcid.org/0000-0002-8739-6225, Junker, Jan Philipp ORCID: https://orcid.org/0000-0002-2826-8290, Heather, Lisa C., Wang, Xiaonan, Gonzalez-Rosa, Juan Manuel, Bakkers, Jeroen and Mommersteeg, Mathilda T.M.
Nature Cardiovascular Research 4
(10): 1363-1380.
October 2025
Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses.
Lesbats, J., Brillac, A., Reisz, J.A., Mukherjee, P., Lhuissier, C., Fernández-Monreal, M., Dupuy, J.W., Sequeira, A., Tioli, G., De La Calle Arregui, C., Pinson, B., Wendisch, D., Rousseau, B., Efeyan, A., Sander, L.E., D'Alessandro, A. and Garaude, J.
Nature 640
(8058): 524-533.
10 April 2025
The novel MuRF2 target SNX5 regulates PKA activity through stabilization of RI-α and controls myogenic differentiation.
Li, Ning, Hamati, Jida, Li, Yi, Brinschwitz, Björn, Ghait, Mohamed, Martin, Elisa, Lodka, Dörte ORCID: https://orcid.org/0009-0009-3317-6487, Hammer, Elke, Fielitz, Britta, Völker, Uwe, Dittmar, Gunnar ORCID: https://orcid.org/0000-0003-3647-8623, Sommer, Thomas ORCID: https://orcid.org/0000-0001-9990-5202, Luft, Friedrich C. ORCID: https://orcid.org/0000-0002-8635-1199 and Fielitz, Jens ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 16
(5): e70103.
October 2025
DeBCR: trained model weights for fluorescence microscopy image enhancement.
Li, Rui ORCID: https://orcid.org/0000-0002-3085-5267, Yushkevich, Artsemi ORCID: https://orcid.org/0000-0002-8729-9281, Chu, Xiaofeng ORCID: https://orcid.org/0000-0001-6801-3949, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Yakimovich, Artur ORCID: https://orcid.org/0000-0003-2458-4904
[Dataset]
21 November 2025
Pressure-adjusted static compression: aerobic metabolism and microvascular perfusion in the context of chemotherapy-induced neuropathy.
Lischke, Betty, Mohammad, Josef, Rheimann, René, Schraplau, Anne, Haspel, Antonia, Schmidt-Lucke, André, Ochsenreither, Sebastian, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Habazettl, Helmut and Schmidt-Lucke, Caroline
Cancer & Metabolism 13
(1): 40.
December 2025
Spatiotemporal dynamics of tumor microenvironment remodeling.
Lisek, Kamil ORCID: https://orcid.org/0000-0002-2406-8830, Theurillat, Ilan ORCID: https://orcid.org/0000-0002-1125-1951, Pentimalli, Tancredi Massimo ORCID: https://orcid.org/0000-0002-8461-7918, Beier, Svea ORCID: https://orcid.org/0009-0006-6473-8487, León-Periñán, Daniel ORCID: https://orcid.org/0000-0002-7970-0362, Antonatou, Anna, Dubnov, Serafima, Müller, Marion, Hubl, Florian, Xhuri, Artemis, Romanowicz, Hanna, Smolarz, Beata, Montaudon, Elodie, Raimundo, Sandra ORCID: https://orcid.org/0009-0000-3353-5456, Margineanu, Anca ORCID: https://orcid.org/0000-0002-6634-9729, Schott, Marie ORCID: https://orcid.org/0009-0000-7393-2421, Kunz, Séverine ORCID: https://orcid.org/0000-0002-0131-3506, Marangoni, Elisabetta, Karaiskos, Nikos ORCID: https://orcid.org/0000-0001-7771-3947, Nitzan, Mor, Birchmeier, Walter ORCID: https://orcid.org/0000-0003-1173-0829 and Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332
bioRxiv
: 2025.07.15.662972.
18 July 2025
Spatiotemporal dynamics of tumor microenvironment remodeling.
Lisek, Kamil ORCID: https://orcid.org/0000-0002-2406-8830, Theurillat, Ilan ORCID: https://orcid.org/0000-0002-1125-1951, Pentimalli, Tancredi Massimo ORCID: https://orcid.org/0000-0002-8461-7918, Beier, Svea ORCID: https://orcid.org/0009-0006-6473-8487, León-Periñán, Daniel ORCID: https://orcid.org/0000-0002-7970-0362, Antonatou, Anna, Dubnov, Serafima, Müller, Marion, Hubl, Florian, Xhuri, Artemis, Romanowicz, Hanna, Smolarz, Beata, Montaudon, Elodie, Raimundo, Sandra ORCID: https://orcid.org/0009-0000-3353-5456, Margineanu, Anca ORCID: https://orcid.org/0000-0002-6634-9729, Schott, Marie ORCID: https://orcid.org/0009-0000-7393-2421, Kunz, Séverine ORCID: https://orcid.org/0000-0002-0131-3506, Marangoni, Elisabetta, Karaiskos, Nikos ORCID: https://orcid.org/0000-0001-7771-3947, Nitzan, Mor, Birchmeier, Walter ORCID: https://orcid.org/0000-0003-1173-0829 and Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332
bioRxiv
: 2025.07.15.662972.
18 July 2025
Chronic stress stimulates protumor macrophage polarization to propel lung cancer progression.
Liu, Cuilan, Du, Hengwei, Yu, Guoxing, Qi, Jingjing, Dong, Hongliang, Hu, Ruiqi, Wang, Fei, Cui, Bingjie, Chen, Weiwei, Zhang, Qian, Li, Chen, Gao, Ran, Schmitt, Clemens A. ORCID: https://orcid.org/0000-0002-4731-2226, Deng, Jiong, Yu, Yong ORCID: https://orcid.org/0000-0003-1928-2514 and Du, Jing
Cancer Research 85
(13): 2429-2447.
2 July 2025
ST6GAL1 promotes IBD B cell recruitment to the inflamed colon in a CD22-dependent mechanism.
Liu, Li-Juan, Müller, Tanja M., Dedden, Mark, Schramm, Sebastian, Leppkes, Moritz, Atreya, Raja ORCID: https://orcid.org/0000-0002-8556-8433, Atreya, Imke, Neurath, Markus F. and Zundler, Sebastian ORCID: https://orcid.org/0000-0003-0888-2784
Journal of Crohn's & Colitis 19
(7): jjaf097.
July 2025
MYC deregulation sensitizes cancer cells to N-myristoyltransferase inhibition.
Lueg, Gregor A., Zhang, James, Faronato, Monica, Gorelik, Andrii, Kallemeijn, Wouter W., Falciani, Francesco, Walton, Josephine, Houghton, Jack W., Vannini, Silvia, Poon, Evon, Costa, Barbara M., Solari, Roberto, Carr, Robin, Bell, Andrew S., Bartlett, Edward J., Brzezicha, Bernadette, Janz, Martin ORCID: https://orcid.org/0000-0002-1127-0044, Chesler, Louis, Calado, Dinis P. ORCID: https://orcid.org/0000-0001-8239-7184 and Tate, Edward W.
Cell Reports 44
(9): 116180.
23 September 2025
Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma.
Lutz, R. ORCID: https://orcid.org/0009-0004-6214-308X, Poos, A.M. ORCID: https://orcid.org/0009-0009-4325-3933, Solé-Boldo, L. ORCID: https://orcid.org/0000-0002-6974-9066, John, L. ORCID: https://orcid.org/0000-0001-8178-6890, Wagner, J. ORCID: https://orcid.org/0000-0002-5087-3657, Prokoph, N. ORCID: https://orcid.org/0000-0002-6429-9895, Baertsch, M.A. ORCID: https://orcid.org/0000-0002-4000-6904, Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Palit, S., Brobeil, A., Mechtersheimer, G. ORCID: https://orcid.org/0000-0002-9442-3930, Hildenbrand, N. ORCID: https://orcid.org/0000-0002-3988-2018, Hemmer, S. ORCID: https://orcid.org/0009-0000-8696-2099, Steiger, S. ORCID: https://orcid.org/0000-0002-4845-5042, Horn, S., Pepke, W. ORCID: https://orcid.org/0000-0001-9690-4511, Spranz, D.M., Rehnitz, C., Sant, P. ORCID: https://orcid.org/0000-0001-9301-3211, Mallm, J.P. ORCID: https://orcid.org/0000-0002-7059-4030, Friedrich, M.J. ORCID: https://orcid.org/0000-0002-6401-3623, Reichert, P., Huhn, S., Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466, Rippe, K. ORCID: https://orcid.org/0000-0001-9951-9395, Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170, Fröhling, S. ORCID: https://orcid.org/0000-0001-7907-4595, Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Hübschmann, D. ORCID: https://orcid.org/0000-0002-6041-7049, Goldschmidt, H. ORCID: https://orcid.org/0000-0003-0961-0035, Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Sauer, S., Raab, M.S., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051 and Weinhold, N. ORCID: https://orcid.org/0000-0002-5464-3234
Science Immunology 10
(104): eadp6667.
February 2025
Spatial-temporal diversity of extrachromosomal DNA shapes urothelial carcinoma evolution and tumor-immune microenvironment.
Lv, W. ORCID: https://orcid.org/0009-0004-0820-8620, Zeng, Y. ORCID: https://orcid.org/0000-0001-5873-5948, Li, C. ORCID: https://orcid.org/0000-0002-1540-8231, Liang, Y. ORCID: https://orcid.org/0000-0003-3535-3394, Tao, H. ORCID: https://orcid.org/0009-0000-5463-9633, Zhu, Y. ORCID: https://orcid.org/0000-0003-2310-5545, Sui, X. ORCID: https://orcid.org/0000-0001-7004-1973, Li, Y. ORCID: https://orcid.org/0009-0009-6031-518X, Jiang, S. ORCID: https://orcid.org/0009-0006-2889-9697, Gao, Q. ORCID: https://orcid.org/0009-0004-6381-9432, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Prasad, G. ORCID: https://orcid.org/0000-0003-4590-1278, Wang, Y. ORCID: https://orcid.org/0000-0002-0068-5148, Zhou, R. ORCID: https://orcid.org/0000-0003-3485-8294, Xu, Z. ORCID: https://orcid.org/0000-0002-8999-3234, Pan, X. ORCID: https://orcid.org/0000-0002-2688-9245, Chen, L. ORCID: https://orcid.org/0009-0000-5602-4704, Xiang, X. ORCID: https://orcid.org/0000-0002-5590-7289, Teng, H. ORCID: https://orcid.org/0000-0001-9952-3618, Sun, C. ORCID: https://orcid.org/0000-0003-2469-1638, Qin, T. ORCID: https://orcid.org/0000-0002-5897-871X, Dong, W. ORCID: https://orcid.org/0000-0001-6386-0831, Li, Y. ORCID: https://orcid.org/0000-0002-4843-5447, Lan, X. ORCID: https://orcid.org/0000-0002-6523-046X, Li, X. ORCID: https://orcid.org/0000-0002-7030-0856, Lin, L. ORCID: https://orcid.org/0000-0002-7546-4948, Bolund, L. ORCID: https://orcid.org/0009-0005-5995-8197, Yang, H. ORCID: https://orcid.org/0000-0002-0858-3410, Verhaak, R.G.W. ORCID: https://orcid.org/0000-0003-2773-0436, Faltas, B.M. ORCID: https://orcid.org/0000-0002-6432-1693, Hansen, J.B. ORCID: https://orcid.org/0000-0001-5249-2586, Wu, S. ORCID: https://orcid.org/0000-0001-8329-7492, Mischel, P.S. ORCID: https://orcid.org/0000-0002-4560-2211, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Bafna, V. ORCID: https://orcid.org/0000-0002-5810-6241, Luebeck, J. ORCID: https://orcid.org/0000-0003-4391-979X, Regenberg, B. ORCID: https://orcid.org/0000-0003-4996-7012, Luo, Y. ORCID: https://orcid.org/0000-0002-0007-7759, Lin, C. ORCID: https://orcid.org/0000-0001-5225-3518 and Han, P. ORCID: https://orcid.org/0000-0002-3405-087X
Cancer Discovery 15
(6): 1225-1246.
3 June 2025
Supplementary Tables 1-24 from Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment.
Lv, Wei, Zeng, Yuche, Li, Conghui, Liang, Yuan, Tao, Huiying, Zhu, Yanfen, Sui, Xiaolong, Li, Yue, Jiang, Shiqi, Gao, Qingqing, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Prasad, Gino, Wang, Yuanmei, Zhou, Run, Xu, Zhe, Pan, Xiaoguang, Chen, Linlin, Xiang, Xi, Teng, Huajing, Sun, Chaoyang, Li, Wei, Qin, Tianyu, Dong, Wei, Li, Yongwei, Lan, Xun, Li, Xuesong, Lin, Lin, Bolund, Lars, Yang, Huanming, Verhaak, Roel G.W., Faltas, Bishoy M., Hansen, Jacob B., Wu, Sihan, Mischel, Paul S., Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X, Bafna, Vineet, Luebeck, Jens, Regenberg, Birgitte, Luo, Yonglun, Lin, Chunhua and Han, Peng
[Dataset]
3 June 2025
The cellular and molecular cardiac tissue responses in human inflammatory cardiomyopathies after SARS-CoV-2 infection and COVID-19 vaccination.
Maatz, H. ORCID: https://orcid.org/0000-0002-9232-6272, Lindberg, E.L. ORCID: https://orcid.org/0000-0002-2979-433X, Adami, E. ORCID: https://orcid.org/0000-0002-1813-6681, López-Anguita, N. ORCID: https://orcid.org/0000-0003-3373-7191, Perdomo-Sabogal, A. ORCID: https://orcid.org/0000-0002-1677-8963, Cócera Ortega, L., Patone, G. ORCID: https://orcid.org/0000-0002-7242-0341, Reichart, D., Myronova, A. ORCID: https://orcid.org/0000-0003-2886-2588, Schmidt, S., Elsanhoury, A., Klein, O., Kühl, U., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Kurth, F. ORCID: https://orcid.org/0000-0002-3807-473X, Teichmann, S.A. ORCID: https://orcid.org/0000-0002-6294-6366, Oudit, G.Y., Milting, H., Noseda, M. ORCID: https://orcid.org/0000-0002-9553-5029, Seidman, J.G., Seidman, C.E. ORCID: https://orcid.org/0000-0002-9082-3566, Heidecker, B., Sander, L.E. ORCID: https://orcid.org/0000-0002-0476-9947, Sawitzki, B. ORCID: https://orcid.org/0000-0001-8166-8579, Klingel, K., Doeblin, P., Kelle, S. ORCID: https://orcid.org/0000-0001-8105-6599, Van Linthout, S., Hubner, N. ORCID: https://orcid.org/0000-0002-1218-6223 and Tschöpe, C.
Nature Cardiovascular Research 4
(3): 330-345.
March 2025
Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Makhmut, Anuar ORCID: https://orcid.org/0009-0009-6913-4289 and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
26 September 2025
Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets.
Makhmut, Anuar ORCID: https://orcid.org/0009-0009-6913-4289, Mihnea, Paul Dragomir, Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Möbs, Markus, Schmitt, Wolfgang Daniel, Taube, Eliane Tabea and Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081
[Dataset]
5 November 2025
Aberrant inheritance of extrachromosomal DNA amplifications promotes cancer evolution.
Marom, Shir, Lifshits Dayan, Inbar, Narasimha Kadali, Venkata, Giurgiu-Kraljič, Mădălina ORCID: https://orcid.org/0000-0001-5007-7442, Koifman, Gabriela ORCID: https://orcid.org/0000-0002-7728-5214, Hakeny, Karen, Chaurasia, Madhuri, Benamozig, Orlena, Nevo, Reinat ORCID: https://orcid.org/0009-0000-3327-4022, Azuri, Ido ORCID: https://orcid.org/0000-0002-2891-1514, Ryvkin, Julia ORCID: https://orcid.org/0000-0002-1172-8350, Rotkopf, Ron ORCID: https://orcid.org/0000-0001-9503-7348, Stelzer, Gil ORCID: https://orcid.org/0000-0001-9368-4912, Oniashvili, Nino, Mardoukh, Jacques, Pollock, Sarah, Iremadze, Nika, Shipony, Zohar ORCID: https://orcid.org/0000-0003-2110-8822, Kupervaser, Meital ORCID: https://orcid.org/0000-0002-1068-937X, Wigoda, Noa ORCID: https://orcid.org/0000-0002-4496-881X, Leshkowitz, Dena ORCID: https://orcid.org/0000-0002-4703-2830, Elazar, Zvulun ORCID: https://orcid.org/0000-0002-3231-4464, Berko, Esther ORCID: https://orcid.org/0000-0001-7181-1378, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Shoshani, Ofer ORCID: https://orcid.org/0000-0001-8918-9935
bioRxiv
: 2025.09.19.677276.
21 September 2025
Metabolic traits shape responses to LSD1-directed therapy in glioblastoma tumor-initiating cells.
Marotta, G. ORCID: https://orcid.org/0000-0002-9750-3709, Osti, D. ORCID: https://orcid.org/0000-0001-7794-3400, Zaccheroni, E. ORCID: https://orcid.org/0000-0002-0161-9804, Costanza, B., Faletti, S. ORCID: https://orcid.org/0000-0003-2489-1795, Marinaro, A. ORCID: https://orcid.org/0009-0008-1897-0474, Richichi, C. ORCID: https://orcid.org/0000-0002-3184-0358, Mesa, D. ORCID: https://orcid.org/0009-0003-0290-1136, Rodighiero, S. ORCID: https://orcid.org/0000-0003-4236-7823, Soriani, C. ORCID: https://orcid.org/0000-0003-4363-6597, Migliaccio, E., Ruscitto, F., Priami, C., Sigismund, S. ORCID: https://orcid.org/0000-0002-1396-4453, Manetti, F. ORCID: https://orcid.org/0000-0002-8223-0074, Polli, D. ORCID: https://orcid.org/0000-0002-6960-5708, Beznusenko, G.V., Rusu, M.C. ORCID: https://orcid.org/0000-0002-8369-3580, Favero, F. ORCID: https://orcid.org/0000-0003-3482-8335, Corà, D., Silvestris, D.A., Gallo, A. ORCID: https://orcid.org/0000-0003-0297-1807, Gambino, V., Alfieri, F. ORCID: https://orcid.org/0000-0001-7173-0105, Gandini, S. ORCID: https://orcid.org/0000-0002-1348-4548, Schmitt, M.J. ORCID: https://orcid.org/0000-0001-8296-5858, Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251, Noberini, R. ORCID: https://orcid.org/0000-0002-7267-1079, Bonaldi, T. ORCID: https://orcid.org/0000-0003-3556-1265 and Pelicci, G. ORCID: https://orcid.org/0000-0003-0986-8255
Science Advances 11
(21): eadt2724.
23 May 2025
Clonally expanded effector CD4+ cytotoxic T lymphocytes are associated with severe neurological adverse events after immune checkpoint inhibitor therapy.
Maschmeyer, P. ORCID: https://orcid.org/0000-0002-1705-5302, Giguelay, A.M. ORCID: https://orcid.org/0000-0003-0417-1109 and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
[Dataset]
3 December 2025
Ongoing genome doubling shapes evolvability and immunity in ovarian cancer.
McPherson, Andrew, Vázquez-García, Ignacio, Myers, Matthew A., Al-Rawi, Duaa H., Zatzman, Matthew, Weiner, Adam C., Freeman, Samuel, Mohibullah, Neeman, Satas, Gryte, Williams, Marc J., Ceglia, Nicholas, Norkūnaitė, Danguolė, Zhang, Allen W., Li, Jun, Lim, Jamie L.P., Wu, Michelle, Choi, Seongmin, Havasov, Eliyahu, Grewal, Diljot, Shi, Hongyu, Kim, Minsoo, Schwarz, Roland F. ORCID: https://orcid.org/0000-0001-9155-4268, Kaufmann, Tom ORCID: https://orcid.org/0000-0003-4374-1338, Dinh, Khanh Ngoc, Uhlitz, Florian, Tran, Julie, Wu, Yushi, Patel, Ruchi, Ramakrishnan, Satish, Kim, DooA, Clarke, Justin, Green, Hunter, Ali, Emily, DiBona, Melody, Varice, Nancy, Kundra, Ritika, Broach, Vance, Gardner, Ginger J., Roche, Kara Long, Sonoda, Yukio, Zivanovic, Oliver, Kim, Sarah H., Grisham, Rachel N., Liu, Ying L, Viale, Agnes, Rusk, Nicole, Lakhman, Yulia, Ellenson, Lora H., Tavaré, Simon, Aparicio, Samuel, Chi, Dennis S., Aghajanian, Carol, Abu-Rustum, Nadeem R., Friedman, Claire F., Zamarin, Dmitriy, Weigelt, Britta, Bakhoum, Samuel F. and Shah, Sohrab P.
Nature 644
(8078): 1078-1087.
28 August 2025
Detergent-free reconstitution of transmembrane proteins in giant liposomes of complex curvature by the Synthetic Membrane Transfer.
Meena, Hemraj, Zdanowicz, Rafal ORCID: https://orcid.org/0009-0005-5694-2704, Bock-Bierbaum, Tobias ORCID: https://orcid.org/0000-0003-0843-2716, Stephan, Till ORCID: https://orcid.org/0000-0002-4032-7644, Ottsen Knudsen, Sofie Dorothea, Jakobs, Stefan ORCID: https://orcid.org/0000-0002-8028-3121, Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, Pedersen, Per A. and De Franceschi, Nicola ORCID: https://orcid.org/0000-0002-7221-613X
bioRxiv
: 2025.08.23.671895.
23 August 2025
Anti-CD19 CAR T cell therapy induces antibody seroconversion and complete B cell depletion in the bone marrow of a therapy-refractory patient with ANCA-associated vasculitis.
Minopoulou, I., Wilhelm, A., Albach, F., Kleyer, A., Wiebe, E., Schallenberg, S., Fleischmann, A., Frick, M., Damm, F., Gogolok, J., Serve, S., Locher, B.N., Borie, D., Casteleyn, V., Biesen, R., Dörner, T., Alexander, T., Zernicke, J., Movassaghi, K., Hütter-Krönke, M.L., Schrezenmeier, E. ORCID: https://orcid.org/0000-0002-0016-7885, Schreiber, A. ORCID: https://orcid.org/0000-0003-1244-6379, Schneider, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Krönke, G., Penack, O. and Simon, D.
Annals of the Rheumatic Diseases 84
(3): e4-e7.
March 2025
Structural basis for membrane targeting and secretion of legionella SidE ubiquitin ligases.
Misra, Mohit ORCID: https://orcid.org/0000-0001-6309-8066, Mukherjee, Rukmini, Bhattacharya, Anshu, Weng, Tsai-Hsuan ORCID: https://orcid.org/0000-0002-3708-6384, Li, Chuang, Chen, Wenbo, van Ek, Larissa ORCID: https://orcid.org/0000-0002-8047-1560, Mohammed, Ahmed, Cristiani, Alberto, Liu, Yaobin, Pomirska, Julia, Vidov, Adela, Grewe, Diana, van der Heden van Noort, Gerbrand ORCID: https://orcid.org/0000-0001-5955-6431, Hummer, Gerhard ORCID: https://orcid.org/0000-0001-7768-746X, Gavin, Anne-Claude ORCID: https://orcid.org/0000-0003-4917-2340, Safarian, Schara, Luo, Zhao-Qing ORCID: https://orcid.org/0000-0001-8890-6621, Bhaskara, Ramachandra ORCID: https://orcid.org/0000-0002-7742-0391, Svergun, Dmitri, Kudryashev, Misha ORCID: https://orcid.org/0000-0003-3550-6274 and Dikic, Ivan ORCID: https://orcid.org/0000-0001-8156-9511
Research Square
: rs.3.rs-6524297/v1.
12 May 2025
Extrachromosomal DNA-driven oncogene dosage heterogeneity promotes rapid adaptation to therapy in MYCN-amplified cancers.
Montuori, Giulia, Tu, Fengyu, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Schmargon, Rachel ORCID: https://orcid.org/0009-0009-3535-7185, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Helmsauer, Konstantin ORCID: https://orcid.org/0000-0003-0773-4114, Hui, Hui, Mandal, Susmita, Purshouse, Karin, Fankhänel, Lara, Bosco, Bartolomeo ORCID: https://orcid.org/0000-0002-3069-714X, Spanjaard, Bastiaan ORCID: https://orcid.org/0000-0003-1309-8839, Seyboldt, Hannah, Grunewald, Laura, Schmitt, Matthias Jürgen ORCID: https://orcid.org/0000-0001-8296-5858, Gürgen, Dennis, Buck, Viktoria, Rosenfeldt, Mathias T, Dubois, Frank P.B. ORCID: https://orcid.org/0000-0002-7654-6208, Schallenberg, Simon, Lehmann, Annika, Theißen, Jessica, Taschner-Mandl, Sabine, Koch, Arend, Hundsdoerfer, Patrick, Künkele, Annette, Eggert, Angelika, Fischer, Matthias, Gargiulo, Gaetano ORCID: https://orcid.org/0000-0001-5414-4251, Krieger, Teresa G, Chavez, Lukas, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Werner, Benjamin, Huang, Weini, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Dörr, Jan R. ORCID: https://orcid.org/0000-0002-4927-6548
Cancer Discovery 15
(10): 2054-2077.
6 October 2025
Table S1 from Extrachromosomal DNA–Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers.
Montuori, Giulia, Tu, Fengyu, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Schmargon, Rachel ORCID: https://orcid.org/0009-0009-3535-7185, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Helmsauer, Konstantin ORCID: https://orcid.org/0000-0003-0773-4114, Hui, Hui, Mandal, Susmita, Purshouse, Karin, Fankhänel, Lara, Bosco, Bartolomeo ORCID: https://orcid.org/0000-0002-3069-714X, Spanjaard, Bastiaan ORCID: https://orcid.org/0000-0003-1309-8839, Seyboldt, Hannah, Grunewald, Laura, Schmitt, Matthias Jürgen ORCID: https://orcid.org/0000-0001-8296-5858, Gürgen, Dennis, Buck, Viktoria, Rosenfeldt, Mathias T., Dubois, Frank P.B. ORCID: https://orcid.org/0000-0002-7654-6208, Schallenberg, Simon, Lehmann, Annika, Theißen, Jessica, Taschner-Mandl, Sabine, Koch, Arend, Hundsdoerfer, Patrick, Künkele, Annette, Eggert, Angelika, Fischer, Matthias, Gargiulo, Gaetano ORCID: https://orcid.org/0000-0001-5414-4251, Krieger, Teresa G., Chavez, Lukas, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Werner, Benjamin, Huang, Weini, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Dörr, Jan R. ORCID: https://orcid.org/0000-0002-4927-6548
[Dataset]
6 October 2025
Table S2 from Extrachromosomal DNA–Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers.
Montuori, Giulia, Tu, Fengyu, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Schmargon, Rachel ORCID: https://orcid.org/0009-0009-3535-7185, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Helmsauer, Konstantin ORCID: https://orcid.org/0000-0003-0773-4114, Hui, Hui, Mandal, Susmita, Purshouse, Karin, Fankhänel, Lara, Bosco, Bartolomeo ORCID: https://orcid.org/0000-0002-3069-714X, Spanjaard, Bastiaan ORCID: https://orcid.org/0000-0003-1309-8839, Seyboldt, Hannah, Grunewald, Laura, Schmitt, Matthias Jürgen ORCID: https://orcid.org/0000-0001-8296-5858, Gürgen, Dennis, Buck, Viktoria, Rosenfeldt, Mathias T., Dubois, Frank P.B. ORCID: https://orcid.org/0000-0002-7654-6208, Schallenberg, Simon, Lehmann, Annika, Theißen, Jessica, Taschner-Mandl, Sabine, Koch, Arend, Hundsdoerfer, Patrick, Künkele, Annette, Eggert, Angelika, Fischer, Matthias, Gargiulo, Gaetano ORCID: https://orcid.org/0000-0001-5414-4251, Krieger, Teresa G., Chavez, Lukas, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Werner, Benjamin, Huang, Weini, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Dörr, Jan R. ORCID: https://orcid.org/0000-0002-4927-6548
[Dataset]
6 October 2025
Table S3 from Extrachromosomal DNA–Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers.
Montuori, Giulia, Tu, Fengyu, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Schmargon, Rachel ORCID: https://orcid.org/0009-0009-3535-7185, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Helmsauer, Konstantin ORCID: https://orcid.org/0000-0003-0773-4114, Hui, Hui, Mandal, Susmita, Purshouse, Karin, Fankhänel, Lara, Bosco, Bartolomeo ORCID: https://orcid.org/0000-0002-3069-714X, Spanjaard, Bastiaan ORCID: https://orcid.org/0000-0003-1309-8839, Seyboldt, Hannah, Grunewald, Laura, Schmitt, Matthias Jürgen ORCID: https://orcid.org/0000-0001-8296-5858, Gürgen, Dennis, Buck, Viktoria, Rosenfeldt, Mathias T., Dubois, Frank P.B. ORCID: https://orcid.org/0000-0002-7654-6208, Schallenberg, Simon, Lehmann, Annika, Theißen, Jessica, Taschner-Mandl, Sabine, Koch, Arend, Hundsdoerfer, Patrick, Künkele, Annette, Eggert, Angelika, Fischer, Matthias, Gargiulo, Gaetano ORCID: https://orcid.org/0000-0001-5414-4251, Krieger, Teresa G., Chavez, Lukas, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Werner, Benjamin, Huang, Weini, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Dörr, Jan R. ORCID: https://orcid.org/0000-0002-4927-6548
[Dataset]
6 October 2025
Table S4 from Extrachromosomal DNA–Driven Oncogene Dosage Heterogeneity Promotes Rapid Adaptation to Therapy in MYCN-Amplified Cancers.
Montuori, Giulia, Tu, Fengyu, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Schmargon, Rachel ORCID: https://orcid.org/0009-0009-3535-7185, Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Helmsauer, Konstantin ORCID: https://orcid.org/0000-0003-0773-4114, Hui, Hui, Mandal, Susmita, Purshouse, Karin, Fankhänel, Lara, Bosco, Bartolomeo ORCID: https://orcid.org/0000-0002-3069-714X, Spanjaard, Bastiaan ORCID: https://orcid.org/0000-0003-1309-8839, Seyboldt, Hannah, Grunewald, Laura, Schmitt, Matthias Jürgen ORCID: https://orcid.org/0000-0001-8296-5858, Gürgen, Dennis, Buck, Viktoria, Rosenfeldt, Mathias T., Dubois, Frank P.B. ORCID: https://orcid.org/0000-0002-7654-6208, Schallenberg, Simon, Lehmann, Annika, Theißen, Jessica, Taschner-Mandl, Sabine, Koch, Arend, Hundsdoerfer, Patrick, Künkele, Annette, Eggert, Angelika, Fischer, Matthias, Gargiulo, Gaetano ORCID: https://orcid.org/0000-0001-5414-4251, Krieger, Teresa G., Chavez, Lukas, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Werner, Benjamin, Huang, Weini, Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Dörr, Jan R. ORCID: https://orcid.org/0000-0002-4927-6548
[Dataset]
6 October 2025
The macromolecular crystallography beamlines of the Helmholtz-Zentrum Berlin at the BESSY II storage ring: history, current status and future directions.
Mueller, U. ORCID: https://orcid.org/0000-0002-7139-0718, Barthel, T. ORCID: https://orcid.org/0000-0002-8747-3112, Benz, L.S. ORCID: https://orcid.org/0000-0001-6369-8707, Bon, V. ORCID: https://orcid.org/0000-0002-9851-5031, Crosskey, T. ORCID: https://orcid.org/0000-0001-9907-8518, Genter Dieguez, C. ORCID: https://orcid.org/0009-0006-3735-8569, Förster, R., Gless, C., Hauß, T., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Hellmig, M. ORCID: https://orcid.org/0000-0003-4999-5718, James, D., Lennartz, F., Oelker, M. ORCID: https://orcid.org/0000-0001-7301-8445, Ovsyannikov, R., Singh, P., Wahl, M.C. ORCID: https://orcid.org/0000-0002-2811-5307, Weber, G. ORCID: https://orcid.org/0000-0003-3624-1060 and Weiss, M.S. ORCID: https://orcid.org/0000-0002-2362-7047
Journal of Synchrotron Radiation 32
(3): 766-778.
May 2025
Antagonistic regulation of LINE-1/Alu elements and their repressor APOBEC3B in cellular senescence.
Munot, Daksha, Lu, Yueshuang, Haußmann, Isabell, Najjar, Gregoire, Baur, Charlotte, Singh, Manvendra ORCID: https://orcid.org/0000-0002-8626-5418, Günes, Cagatay, Sauter, Daniel and Arora, Ankit
Mobile DNA 16
(1): 39.
21 October 2025
Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer.
Mzoughi, S., Schwarz, M., Wang, X., Demircioglu, D., Ulukaya, G., Mohammed, K., Zorgati, H., Torre, D., Tomalin, L.E., Di Tullio, F., Company, C. ORCID: https://orcid.org/0000-0002-7975-0642, Dramaretska, Y. ORCID: https://orcid.org/0000-0002-9792-0465, Leushacke, M., Giotti, B., Lannagan, T.R., Lozano-Ojalvo, D., Karras, P., Vermeulen, P.B., Hasson, D., Sebra, R., Tsankov, A.M., Sansom, O.J., Marine, J.C., Barker, N., Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251 and Guccione, E.
Nature Genetics 57
(2): 402-412.
February 2025
Gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice.
Mühlgrabner, V., Plach, A., Holler, J., Leitner, J., Steinberger, P., Dupré, L., Göhring, J. and Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198
Methods in Cell Biology 193
: 127-154.
5 February 2025
Engineering therapeutic regulatory T cells to overexpress G protein-coupled receptor 15 improves functional fitness for in vivo gut homing.
Müller, T.M., Liu, L.J., Wiesinger, M., Neurath, M.F., Voskens, C.J. and Zundler, S.
Gastroenterology 168
(2): 389-392.
February 2025
Differentiation and Dexamethasone Atrophy on C2C12 myotubes.
Nakagawa, S. ORCID: https://orcid.org/0000-0002-9417-9499, Misios, A. and Harnett, D. ORCID: https://orcid.org/0000-0002-9190-128X
[Dataset]
29 September 2025
Early regulation and alternative splicing dynamics in glucocorticoid muscle atrophy revealed by temporal omics in C2C12 myotubes.
Nakagawa, Suzuka ORCID: https://orcid.org/0000-0002-9417-9499, Misios, Aristotelis, Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Jarosch, Ernst ORCID: https://orcid.org/0000-0002-5897-3492, Fielitz, Jens ORCID: https://orcid.org/0000-0001-8522-1045 and Sommer, Thomas ORCID: https://orcid.org/0000-0001-9990-5202
American Journal of Physiology Cell Physiology 329
(4): C1300-C1315.
October 2025
Herpesviruses mimic zygotic genome activation to promote viral replication.
Neugebauer, E., Walter, S., Tan, J., Drayman, N., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, van Gent, M., Pennisi, S., Veratti, P., Stein, K.S., Welker, I., Tay, S., Verjans, G.M.G.M., Timmers, H.T.M., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Ensser, A., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806 and Full, F.
Nature Communications 16
(1): 710.
16 January 2025
openDVP multiplex immunofluorescence demo.
Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799 and Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534
[Dataset]
13 May 2025
Senescent syncytiotrophoblast secretion during early onset preeclampsia.
Nonn, O. ORCID: https://orcid.org/0000-0001-6385-2866, Debnath, O. ORCID: https://orcid.org/0009-0009-2845-055X, Valdes, D.S. ORCID: https://orcid.org/0000-0002-1309-5147, Sallinger, K., Secener, A.K. ORCID: https://orcid.org/0000-0003-4806-2852, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Tiesmeyer, S. ORCID: https://orcid.org/0000-0002-0492-1523, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Kuenzer, T. ORCID: https://orcid.org/0000-0001-6882-1217, Ulrich, J., Maxian, T. ORCID: https://orcid.org/0000-0002-8009-8479, Knöfler, M., Karau, P. ORCID: https://orcid.org/0000-0001-6590-1975, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Kroneis, T. ORCID: https://orcid.org/0000-0002-4761-9340, Frolova, A. ORCID: https://orcid.org/0000-0001-5469-7366, Neuper, L., Haase, N. ORCID: https://orcid.org/0000-0003-0727-1738, Malt, A. ORCID: https://orcid.org/0009-0005-4049-0846, Müller-Bötticher, N. ORCID: https://orcid.org/0000-0001-5103-7282, Kräker, K. ORCID: https://orcid.org/0000-0002-4032-5382, Kedziora, S. ORCID: https://orcid.org/0000-0003-0124-2557, Forstner, D. ORCID: https://orcid.org/0000-0001-5451-7580, Eils, R., Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Haider, S. ORCID: https://orcid.org/0000-0003-2409-1317, Verlohren, S. ORCID: https://orcid.org/0000-0003-3507-8636, Stern, C. ORCID: https://orcid.org/0000-0002-6330-1236, Sugulle, M. ORCID: https://orcid.org/0000-0003-4160-3978, Jones, S. ORCID: https://orcid.org/0000-0002-3106-6155, Thilaganathan, B. ORCID: https://orcid.org/0000-0002-5531-4301, Kaitu'u-Lino, T.J. ORCID: https://orcid.org/0000-0001-6233-9737, Tong, S., Huppertz, B. ORCID: https://orcid.org/0000-0003-4814-2158, El-Heliebi, A. ORCID: https://orcid.org/0000-0002-7679-6856, Staff, A.C. ORCID: https://orcid.org/0000-0001-9247-5721, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Gauster, M. ORCID: https://orcid.org/0000-0003-0386-6857, Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X and Herse, F. ORCID: https://orcid.org/0000-0002-9305-8134
Hypertension 82
(5): 787-799.
May 2025
Unlocking antigen flexibility with widened patient access: CD3FR in off-the-shelf CAR T cells.
Novikova, Nataliia and Huppa, Johannes B. ORCID: https://orcid.org/0000-0003-2634-8198
Molecular Therapy 33
(9): 4029-4031.
3 September 2025
Combining spatial transcriptomics and ECM imaging in 3D for mapping cellular interactions in the tumor microenvironment.
Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Schallenberg, S., León-Periñán, D. ORCID: https://orcid.org/0000-0002-7970-0362, Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Theurillat, I. ORCID: https://orcid.org/0000-0002-1125-1951, Thomas, G., Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Ruff, L., Dernbach, G., Jurmeister, P., Murphy, S., Gregory, M.T., Liang, Y., Cordenonsi, M., Piccolo, S., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Klauschen, F. and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Cell Systems 16
(5): 101261.
21 May 2025
Rewired type I IFN signaling is linked to age-dependent differences in COVID-19.
Petrov, Lev, Brumhard, Sophia, Wisniewski, Sebastian, Georg, Philipp, Hiller, Anna, Astaburuaga, Rosario, Blüthgen, Nils, Wyler, Emauel ORCID: https://orcid.org/0000-0002-9884-1806, Vogt, Katrin, Dey, Hannah, von Stillfried, Saskia, Iwert, Christina, Bülow, Roman, Maas, Lukas, Langner, Christine, Meyer, Tim, Loske, Jennifer, Eils, Roland, Lehmann, Irina, Ondruschka, Benjamin, Ralser, Markus, Trimpert, Jakob, Boor, Peter, Bedoui, Sammy, Meisel, Christian, Mall, Marcus, Corman, Victor, Sander, Leif Erik, Röhmel, Jobst and Sawitzki, Birgit
[Dataset]
17 June 2025
Rewired type I IFN signaling is linked to age-dependent differences in COVID-19.
Petrov, Lev, Brumhard, Sophia, Wisniewski, Sebastian, Georg, Philipp, Hillus, David, Hiller, Anna, Astaburuaga-García, Rosario, Blüthgen, Nils, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Vogt, Katrin, Dey, Hannah-Philine, von Stillfried, Saskia, Iwert, Christina, Bülow, Roman D., Märkl, Bruno, Maas, Lukas, Langner, Christine, Meyer, Tim, Loske, Jennifer, Eils, Roland, Lehmann, Irina, Ondruschka, Benjamin, Ralser, Markus, Trimpert, Jakob, Boor, Peter, Bedoui, Sammy, Meisel, Christian, Mall, Marcus A., Corman, Victor M., Sander, Leif Erik, Röhmel, Jobst and Sawitzki, Birgit
Cell Reports Medicine 6
(8): 102285.
19 August 2025
MACC1 expression in colorectal cancer is upregulated by loss of epigenetic repression under oxidative stress condition.
Phoyen, Suchittra, Dahlmann, Mathias ORCID: https://orcid.org/0000-0002-0036-5283, Herrmann, Pia, Boonla, Chanchai ORCID: https://orcid.org/0000-0002-6515-4321 and Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X
Cell Biochemistry & Function 43
(8): e70107.
August 2025
Role of intestinal barrier disruption to acute-on-chronic liver failure.
Pohl, J., Aretakis, D., Tacke, F., Engelmann, C. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Seminars in Liver Disease 45
(1): 52-65.
March 2025
Deep coverage multi-omic profiling of C2C12 dexamethasone skeletal muscle atrophy.
Popp, Oliver ORCID: https://orcid.org/0000-0001-6240-4666 and Nakagawa, Suzuka ORCID: https://orcid.org/0000-0002-9417-9499
[Dataset]
14 October 2025
interSeg: accurate prediction of edDNA in interphase cancer cells using deep neural networks.
Prasad, Gino ORCID: https://orcid.org/0000-0003-4590-1278, Rajkumar, Utkrisht ORCID: https://orcid.org/0000-0002-2825-6310, Curtis, Ellis, Wong, Ivy ORCID: https://orcid.org/0000-0002-9761-3422, Yan, Xiaowei ORCID: https://orcid.org/0000-0002-4846-8812, Zhang, Shu ORCID: https://orcid.org/0000-0003-2543-5943, Brückner, Lotte ORCID: https://orcid.org/0000-0002-6155-2277, Turner, Kristen, Wiese, Julie, Wahl, Justin, Hemmati, Homa, Wu, Sihan ORCID: https://orcid.org/0000-0001-8329-7492, Theissen, Jessica, Fischer, Matthias, Chang, Howard ORCID: https://orcid.org/0000-0002-9459-4393, Henssen, Anton ORCID: https://orcid.org/0000-0003-1534-778X, Mischel, Paul ORCID: https://orcid.org/0000-0002-4560-2211 and Bafna, Vineet ORCID: https://orcid.org/0000-0002-5810-6241
[Dataset]
24 November 2025
Neurons to words: a novel method for automated neural network interpretability and alignment.
Puglisi, L.S., Valdés, F. and Metzger, J.J. ORCID: https://orcid.org/0000-0001-6813-4425
In: Thirty-Ninth AAAI Conference on Artificial Intelligence, 25 Feb - 04 Mar, 2025, Philadelphia, PA, USA.
11 April 2025
Georg Friedrich (Fritz) Melchers (27.4.1936–24.2.2025).
Radbruch, A. ORCID: https://orcid.org/0000-0001-5753-0000, Jani, P.K., Winkler, T.H. and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
European Journal of Immunology 55
(6): e52109.
June 2025
The IBEX Knowledge-Base: a central resource for multiplexed imaging techniques.
Radtke, A.J. ORCID: https://orcid.org/0000-0003-4379-8967, Anidi, I.U., Arakkal, L., Arroyo-Mejias, A.J., Beuschel, R.T., Börner, K., Chu, C.J., Clark, B., Clatworthy, M.R., Colautti, J., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Croteau, J., Denha, S., Dever, R., Dutra, W.O., Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534, Fullam, S., Gerner, M.Y., Gola, A., Gollob, K.J., Hernandez, J.M., Hor, J.L., Ichise, H., Jing, Z., Jonigk, D., Kandov, E., Kastenmüller, W., Koenig, J.F.E., Kortekaas, R.K., Kothurkar, A., Kreins, A.Y., Lamborn, I.T., Lin, Y., Morais, K.L.P., Lunich, A., Luz, J.C.S., MacDonald, R.B., Makranz, C., Maltez, V.I., McDonough, J.E., Moriarty, R.V., Ocampo-Godinez, J.M., Olyntho, V.M., Oxenius, A., Padhan, K., Remmert, K., Richoz, N., Schrom, E.C., Shang, W., Shi, L., Shih, R.M., Speranza, E., Stierli, S., Teichmann, S.A., Veres, T.Z., Vierhout, M., Wachter, B.T., Wade-Vallance, A.K., Williams, M., Zangger, N., Germain, R.N. and Yaniv, Zi.
PLoS Biology 23
(3): e3003070.
19 March 2025
ohlerlab/metrics_matter_manuscript_reproducibility: v0.2.0.
Rautenstrauch, Pia ORCID: https://orcid.org/0000-0002-0070-4759
[Dataset]
20 July 2025
Rhabdomyosarcoma of head and neck varies in aggressiveness depending on the specific site of origin.
Rohde, J., Henssen, A. ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, A. and Scheer, M. ORCID: https://orcid.org/0000-0002-0665-6268
Oral Oncology 164
: 107263.
May 2025
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Human sample from Homo sapiens.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752
[Dataset]
2 July 2025
(Submitted)
Prime editing corrects the dilated cardiomyopathy causing RBM20-P633L-mutation in human cardiomyocytes.
Roman, Alexandra ORCID: https://orcid.org/0000-0001-9440-9752, Zimmer, Anja, Gotthardt, Michael ORCID: https://orcid.org/0000-0003-1788-3172, Steinmetz, Lars M., Kühn, Ralf ORCID: https://orcid.org/0000-0003-1694-9803 and Dang, Tu ORCID: https://orcid.org/0009-0001-0138-7599
Molecular Therapy Nucleic Acids 36
(4): 102734.
9 December 2025
Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia.
Ronnacker, J., Grau, M., Klasmeier, M., Klesse, C., Baldauf, H., Abert, S., Berdel, A.F., Füsser, F.T., Sandmann, S., Albring, J., Reicherts, C., Call, S., Marx, J., Floeth, M., Eßeling, E., Kolloch, L., Berning, P., Scheller, A., Wethmar, K., Schmidt, H., Schlüter, B., Berdel, W.E., Ostendorf, B.N. ORCID: https://orcid.org/0000-0003-4492-9252, Tavazoie, S.F., Mikesch, J.H., Lenz, G., Fleischhauer, K., Schetelig, J., Stelljes, M. and Schliemann, C.
Blood 145
(17): 1943-1956.
24 April 2025
Selection of therapeutically effective T-cell receptors from the diverse tumor-bearing repertoire.
Rosenberger, L., Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128, Anastasopoulou, V., Wolf, S.P. ORCID: https://orcid.org/0009-0008-2723-695X, Drousch, K., Moewes, C., Feng, X., Cao, G., Huang, J. ORCID: https://orcid.org/0000-0003-0271-4384, Yew, P.Y., Strønen, E. ORCID: https://orcid.org/0000-0001-9314-9389, Kato, T., Saligrama, N., Olweus, J., Nakamura, Y., Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Schreiber, H. and Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142
Journal for ImmunoTherapy of Cancer 13
(5): e011351.
2 May 2025
Characterizing uveal melanoma patients with peritoneal metastases: a retrospective single-center analysis.
Rosnev, S. ORCID: https://orcid.org/0000-0003-0256-7038, Peuker, C.A. ORCID: https://orcid.org/0000-0002-0957-2166, Piwonski, I., Ihlow, J., Leyvraz, S., Klingberg, J., Horst, D., Joosten, M., Möbs, M., Joussen, A.M., de Bucourt, M., Keilholz, U., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Ochsenreither, S. and Rittig, S.M.
European Journal of Cancer 218
: 115280.
11 March 2025
Reduced monocytic IL10 expression in PD1 inhibitor-treated patients is a harbinger of severe immune-related adverse events.
Rosnev, S. ORCID: https://orcid.org/0000-0003-0256-7038, Sterner, B. ORCID: https://orcid.org/0000-0001-8882-3885, Schiele, P. ORCID: https://orcid.org/0000-0002-2342-3597, Kolling, S., Martin, M. ORCID: https://orcid.org/0000-0001-9549-6843, Flörcken, A., Erber, B., Wittenbecher, F., Kofla, G., Kurreck, A., Lang, T.J.L. ORCID: https://orcid.org/0000-0003-0566-196X, von Einem, J.C. ORCID: https://orcid.org/0000-0001-8843-9541, de Santis, M., Pelzer, U. ORCID: https://orcid.org/0000-0001-9213-2737, Stintzing, S. ORCID: https://orcid.org/0000-0002-3297-5801, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Klinghammer, K. ORCID: https://orcid.org/0000-0001-6425-4833, Geisel, D. ORCID: https://orcid.org/0000-0001-7348-0971, Ochsenreither, S., Frentsch, M. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
European Journal of Cancer 217
: 115252.
25 February 2025
The next generation of in situ multi-omics.
Salla, M. ORCID: https://orcid.org/0009-0003-8453-2935, Penkert, K. ORCID: https://orcid.org/0000-0002-9948-533X and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
Nature Methods 22
(3): 461-462.
March 2025
Cryo-mtscATAC-seq for single-cell mitochondrial DNA genotyping and clonal tracing in archived human tissues.
Salla, Maren ORCID: https://orcid.org/0009-0003-8453-2935, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Cotta, Marie ORCID: https://orcid.org/0000-0002-2589-3189, Friebel, Ekaterina ORCID: https://orcid.org/0000-0003-1419-2376, Campo-Garcia, Juliana, Charalambous, Georgia, Bueno, Roemel Jeusep, Lieu, Dustin, Dabek, Patryk, Helmuth, Ashley, Tellides, George, Assi, Roland, Bankov, Katrin, Lodrini, Marco, Deubzer, Hedwig ORCID: https://orcid.org/0000-0002-6115-4893, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Chung, Hattie ORCID: https://orcid.org/0000-0001-8417-5606, Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Capper, David, Heppner, Frank ORCID: https://orcid.org/0000-0001-9816-8917, Starossom, Sarah C. ORCID: https://orcid.org/0000-0001-7935-9910, Lareau, Caleb A. ORCID: https://orcid.org/0000-0003-4179-4807, Liu, Ilon ORCID: https://orcid.org/0000-0002-6186-3630 and Ludwig, Leif S. ORCID: https://orcid.org/0000-0002-2916-2164
bioRxiv
: 2025.09.17.675534.
20 September 2025
Mapping dihydropteroate synthase evolvability through identification of a novel evolutionarily critical substructure.
Sanyal, D., Shivram, A, Pandey, D., Banerjee, S. ORCID: https://orcid.org/0000-0002-3747-8425, Uversky, V.N., Muzata, D., Chivukula, A., Jasuja, R., Chattopadhyay, K. and Chowdhury, S.
International Journal of Biological Macromolecules 311
(Part 2): 143325.
June 2025
AI-powered spatial cell phenomics enhances risk stratification in non-small cell lung cancer.
Schallenberg, Simon, Dernbach, Gabriel, Ruane, Sharon, Jurmeister, Philipp ORCID: https://orcid.org/0000-0001-7745-3794, Böhm, Cornelius ORCID: https://orcid.org/0009-0007-3754-4182, Standvoss, Kai, Ghosh, Sandip ORCID: https://orcid.org/0009-0008-7342-1064, Frentsch, Marco, Dragomir, Mihnea P ORCID: https://orcid.org/0000-0002-5550-3516, Keyl, Philipp G ORCID: https://orcid.org/0000-0002-5472-4683, Friedrich, Corinna ORCID: https://orcid.org/0000-0002-5586-1989, Na, Il-Kang ORCID: https://orcid.org/0000-0001-9902-5424, Merkelbach-Bruse, Sabine, Quaas, Alexander, Frost, Nikolaj ORCID: https://orcid.org/0000-0001-7452-7129, Boschung, Kyrill, Randerath, Winfried, Schlachtenberger, Georg, Heldwein, Matthias ORCID: https://orcid.org/0000-0002-2084-795X, Keilholz, Ulrich, Hekmat, Khosro, Rückert, Jens-Carsten, Büttner, Reinhard ORCID: https://orcid.org/0000-0001-8806-4786, Vasaturo, Angela, Horst, David, Ruff, Lukas, Alber, Maximilian, Müller, Klaus-Robert ORCID: https://orcid.org/0000-0002-3861-7685 and Klauschen, Frederick ORCID: https://orcid.org/0000-0002-9131-2389
Nature Communications 16
(1): 9701.
3 November 2025
Clonal tracing with somatic epimutations reveals dynamics of blood ageing.
Scherer, M., Singh, I., Braun, M.M., Szu-Tu, C., Sanchez Sanchez, P., Lindenhofer, D., Jakobsen, N.A., Körber, V., Kardorff, M., Nitsch, L. ORCID: https://orcid.org/0000-0003-0775-1969, Kautz, P. ORCID: https://orcid.org/0000-0002-9658-1676, Rühle, J., Bianchi, A., Cozzuto, L., Frömel, R., Beneyto-Calabuig, S., Lareau, C. ORCID: https://orcid.org/0000-0003-4179-4807, Satpathy, A.T., Beekman, R., Steinmetz, L.M., Raffel, S., Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Vyas, P., Rodriguez-Fraticelli, A. and Velten, L.
Nature 643
(8071): 478-487.
10 July 2025
Flow cytometric assessment of FcγRIIIa-V158F polymorphisms and NK cell mediated ADCC revealed reduced NK cell functionality in colorectal cancer patients.
Schiele, P. ORCID: https://orcid.org/0000-0002-2342-3597, Kolling, S. ORCID: https://orcid.org/0000-0002-0113-5551, Rosnev, S. ORCID: https://orcid.org/0000-0003-0256-7038, Junkuhn, C. ORCID: https://orcid.org/0009-0005-7401-6421, Walter, A.L., Von Einem, J.C. ORCID: https://orcid.org/0000-0001-8843-9541, Stintzing, S. ORCID: https://orcid.org/0000-0002-3297-5801, Schöning, W., Sauer, I.M. ORCID: https://orcid.org/0000-0001-9355-937X, Modest, D.P., Heinrich, K., Weiss, L., Heinemann, V., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Frentsch, M. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Cells 14
(1): 32.
January 2025
CD8(+) T cell-derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells.
Schiele, P., Sada Japp, A. ORCID: https://orcid.org/0000-0001-8106-8987, Stark, R., Sattelberg, J.J., Nikolaou, C., Kornhuber, G., Abbasi, P., Ding, N., Rosnev, S., Meinke, S., Mühle, K., Loyal, L., Braun, J., Dingeldey, M., Durlanik, S., Matzmohr, N., Ponikwicka-Tyszko, D., Wolczynski, S., Rahman, N.A., Taniuchi, I., Schlickeiser, S., Giesecke-Thiel, C., Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Thiel, A. and Frentsch, M.
Science Advances 11
(21): eadr9331.
23 May 2025
Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development.
Schindler, Magdalena, Feregrino, Christian ORCID: https://orcid.org/0000-0003-0300-5483, Aldrovandi, Silvia, Lo, Bai-Wei, Monaco, Anna A. ORCID: https://orcid.org/0009-0000-5779-3505, Ringel, Alessa R., Morales, Ariadna E., Zehnder, Tobias, Behncke, Rose Yinghan, Glaser, Juliane, Barclay, Alexander, Andrey, Guillaume, Kragesteen, Bjørt K., Hägerling, René, Haas, Stefan A., Vingron, Martin, Ulitsky, Igor ORCID: https://orcid.org/0000-0003-0555-6561, Marti-Renom, Marc A., Hechavarria, Julio, Fasel, Nicolas, Hiller, Michael, Lupiáñez, Darío G. ORCID: https://orcid.org/0000-0002-3165-036X, Mundlos, Stefan and Real, Francisca M. ORCID: https://orcid.org/0000-0003-0692-2260
Nature Ecology & Evolution 9
(9): 1626-1642.
September 2025
Chemotherapy-free combination of ibrutinib and obinutuzumab for untreated advanced follicular lymphoma: results of a phase II study from the German Lymphoma Alliance.
Schmidt, Christian, Scheubeck, Gabriel, Jurinovic, Vindi, Sökler, Martin, Forstpointner, Roswitha, Buske, Christian, Viardot, Andreas, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Graeven, Ullrich, Marks, Reinhard, Hänel, Mathias, Liersch, Rüdiger, Dürig, Jan, Pott, Christiane, Hoster, Eva, Unterhalt, Michael and Hiddemann, Wolfgang
Haematologica 110
(12): 3022-3031.
1 December 2025
Persistence and/or senescence: not so lasting at last?
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Research 85
(1): 7-9.
2 January 2025
CD4+T-cells create a stable mechanical environment for force-sensitive TCR:pMHC interactions.
Schrangl, Lukas ORCID: https://orcid.org/0000-0002-0420-7872, Kellner, Florian, Platzer, René ORCID: https://orcid.org/0009-0001-3399-4721, Mühlgrabner, Vanessa, Hubinger, Paul, Wieland, Josephine, Obst, Reinhard, Toca-Herrera, José L. ORCID: https://orcid.org/0000-0001-8951-2616, Huppa, Johannes B. ORCID: https://orcid.org/0000-0003-2634-8198, Schütz, Gerhard J. ORCID: https://orcid.org/0000-0003-1542-1089 and Göhring, Janett
Nature Communications 16
(1): 7577.
15 August 2025
Novel tetrazolo-pyridazine-based MACC1 transcriptional inhibitor reduces NFκb signaling pathway as key antimetastatic mechanism of action.
Schöpe, Paul Curtis ORCID: https://orcid.org/0000-0002-5512-8832, Dahlmann, Mathias ORCID: https://orcid.org/0000-0002-0036-5283, Kobelt, Dennis ORCID: https://orcid.org/0000-0002-9373-0648, Gohlke, Bjoern-O, Shoman, Abdelrhman M. ORCID: https://orcid.org/0009-0005-4991-6209, Walther, Wolfgang ORCID: https://orcid.org/0000-0003-2884-0231, Preissner, Robert ORCID: https://orcid.org/0000-0002-2407-1087, Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330 and Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X
Journal of Biotechnology and Biomedicine 8
(4): 356-369.
30 December 2025
Novel high-throughput screen identified S100A4 inhibitors for anti-metastatic therapy.
Schöpe, Paul Curtis ORCID: https://orcid.org/0000-0002-5512-8832, Heisterkamp, Nina, Schütz, Devin, Mastrobuoni, Guido ORCID: https://orcid.org/0000-0003-4509-1295, Putzker, Kerstin, Uhrig, Ulrike, Walther, Wolfgang ORCID: https://orcid.org/0000-0003-2360-1370, Kempa, Stefan ORCID: https://orcid.org/0000-0002-0696-9299, Nazaré, Marc ORCID: https://orcid.org/0000-0002-1602-2330, Kobelt, Dennis ORCID: https://orcid.org/0000-0002-9373-0648 and Stein, Ulrike ORCID: https://orcid.org/0000-0001-7006-282X
International Journal of Biological Sciences 21
(10): 4683-4700.
2025
Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform.
Selcen, Selen ORCID: https://orcid.org/0009-0006-4006-4369, Wieland, Lena ORCID: https://orcid.org/0009-0006-5969-1012, De Oliveira, Tiago ORCID: https://orcid.org/0000-0002-2502-7897, Ghadimi, Michael, Conradi, Lena-Christin, Schneider, Günter ORCID: https://orcid.org/0000-0003-1840-4508, Witte, Leonie ORCID: https://orcid.org/0000-0003-2154-937X and Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872
Cell Death Discovery 11
(1): 368.
6 August 2025
DuplexDiscoverer: a computational method for the analysis of experimental duplex RNA-RNA interaction data.
Semenchenko, E. ORCID: https://orcid.org/0009-0007-5306-076X, Tsybulsky, V. ORCID: https://orcid.org/0009-0002-4141-6291 and Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479
Nucleic Acids Research 53
(7): gkaf266.
April 2025
Safety and efficacy of glofitamab for relapsed/refractory large B-cell lymphoma in a multinational real-world study.
Shumilov, E. ORCID: https://orcid.org/0000-0003-0178-1729, Wurm-Kuczera, R., Kerkhoff, A. ORCID: https://orcid.org/0000-0001-6904-2821, Wang, M. ORCID: https://orcid.org/0009-0006-1426-4594, Melchardt, T. ORCID: https://orcid.org/0000-0002-0122-3631, Holtick, U. ORCID: https://orcid.org/0000-0002-5543-0257, Bacher, U. ORCID: https://orcid.org/0000-0001-8771-947X, Staber, P.B. ORCID: https://orcid.org/0000-0001-6729-7708, Mazzeo, P. ORCID: https://orcid.org/0000-0001-6317-0216, Leng, C. ORCID: https://orcid.org/0009-0006-4007-9122, Böckle, D. ORCID: https://orcid.org/0000-0002-1783-9641, Hölscher, A.S. ORCID: https://orcid.org/0009-0004-8994-1137, Kauer, J. ORCID: https://orcid.org/0000-0003-1632-0167, Rotter, N. ORCID: https://orcid.org/0009-0009-9813-5344, Vucinic, V. ORCID: https://orcid.org/0000-0002-8398-285X, Rudzki, J.D. ORCID: https://orcid.org/0000-0001-7963-3385, Nachbaur, D. ORCID: https://orcid.org/0009-0006-6243-915X, Bücklein, V.L. ORCID: https://orcid.org/0000-0001-7391-7280, Schnetzke, U. ORCID: https://orcid.org/0000-0001-7455-8988, Krämer, I. ORCID: https://orcid.org/0000-0003-1667-4109, Wille, K. ORCID: https://orcid.org/0000-0002-7682-8563, Hasse, A., von Tresckow, B. ORCID: https://orcid.org/0000-0003-1410-4487, Hänel, M. ORCID: https://orcid.org/0000-0002-4767-3275, Koenecke, C. ORCID: https://orcid.org/0000-0001-7025-1735, Velazquez, G.F. ORCID: https://orcid.org/0000-0003-2884-3432, Viardot, A. ORCID: https://orcid.org/0000-0001-9593-6327, Schmid, C. ORCID: https://orcid.org/0000-0001-7070-487X, Thurner, L. ORCID: https://orcid.org/0000-0002-8167-2989, Wolf, D. ORCID: https://orcid.org/0000-0002-4761-075X, Subklewe, M. ORCID: https://orcid.org/0000-0003-3905-0251, Dreyling, M. ORCID: https://orcid.org/0000-0002-0358-5249, Dreger, P. ORCID: https://orcid.org/0000-0002-7429-8570, Dietrich, S. ORCID: https://orcid.org/0000-0002-0648-1832, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Jäger, U. ORCID: https://orcid.org/0000-0001-9826-1062, Greil, R. ORCID: https://orcid.org/0000-0002-4462-3694, Pabst, T. ORCID: https://orcid.org/0000-0002-6055-5257, Lenz, G. ORCID: https://orcid.org/0000-0002-4728-1693 and Chapuy, B. ORCID: https://orcid.org/0000-0002-6485-8773
Blood Advances 9
(15): 3865-3877.
12 August 2025
Teclistamab in relapsed systemic sclerosis after autologous haematopoietic stem cell transplantation.
Siegert, E., Biesen, R. ORCID: https://orcid.org/0000-0002-0434-7832, Dzamukova, M. ORCID: https://orcid.org/0000-0002-2389-3222, Furth, C., Probst, M. ORCID: https://orcid.org/0009-0004-3390-6789, Doellinger, F. ORCID: https://orcid.org/0000-0003-3661-8569, Walter-Rittel, T., Fleischmann, A., Wilhelm, A., Beenken, A.E., Wiebe, E., Pecher, A.C. ORCID: https://orcid.org/0000-0003-0201-0686, Henes, J. ORCID: https://orcid.org/0000-0002-8385-6861, Florian, S., Simon, D., Kleyer, A., Burmester, G.R., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Krönke, J., Krönke, G. and Alexander, T. ORCID: https://orcid.org/0000-0003-1193-0097
Annals of the Rheumatic Diseases 84
(4): 653-656.
April 2025
A computational model elucidates the effects of oncogene-induced expression alterations on the energy metabolism of neuroblastoma.
Simon, Mareike ORCID: https://orcid.org/0000-0001-7213-9499, Benary, Uwe ORCID: https://orcid.org/0000-0001-7801-8639, Baum, Katharina ORCID: https://orcid.org/0000-0001-7256-0566, Schramm, Alexander and Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868
Scientific Reports 15
(1): 32708.
24 September 2025
Simon2025 - Neuroblastoma energy metabolism.
Simon, Mareike ORCID: https://orcid.org/0000-0001-7213-9499, Benary, Uwe ORCID: https://orcid.org/0000-0001-7801-8639, Baum, Katharina ORCID: https://orcid.org/0000-0001-7256-0566, Schramm, Alexander and Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868
[Dataset]
16 April 2025
Slice-PASEF: maximising ion utilisation in LC-MS proteomics.
Sinn, Ludwig R. ORCID: https://orcid.org/0000-0003-4692-0681, Szyrwiel, Lukasz ORCID: https://orcid.org/0000-0003-1983-2950, Grossmann, Justus, Lau, Kate, Faisst, Katharina, Qin, Di ORCID: https://orcid.org/0000-0002-9730-4072, Mutschler, Florian ORCID: https://orcid.org/0009-0002-0992-7171, Khoury, Luke ORCID: https://orcid.org/0000-0001-7794-6812, Leduc, Andrew ORCID: https://orcid.org/0000-0001-6234-0623, Ralser, Markus ORCID: https://orcid.org/0000-0001-9535-7413, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Slavov, Nikolai ORCID: https://orcid.org/0000-0003-2035-1820, Nagaraj, Nagarjuna, Steger, Martin ORCID: https://orcid.org/0000-0003-1637-8190 and Demichev, Vadim ORCID: https://orcid.org/0000-0002-2424-9412
bioRxiv
: 2022.10.31.514544v3.
2 September 2025
Outcomes with intensive treatment for acute myeloid leukemia: an analysis of two decades of data from the HARMONY Alliance.
Sobas, M.A., Turki, A.T., Ramiro, A.V., Sánchez, A.H., Elicegui, J.M., González, T., Melchor, R.A., Abáigar, M., Tur, L., Dall'Olio, D., Sträng, E., Tettero, J.M., Castellani, G., Benner, A., Döhner, K., Thiede, C., Metzeler, K.H., Haferlach, T., Damm, F., Ayala, R., Martínez-López, J., Mills, K.I., Sierra, J., Lehmann, S., Porta, M.G.D., Mayer, J., Reinhardt, D., Medina, R.V., Schulze-Rath, R., Barbus, M., Hernández-Rivas, J.M., Huntly, B.J.P., Ossenkoppele, G., Döhner, H. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Haematologica 110
(5): 1126-1140.
May 2025
Familial Alzheimer disease mutation in SORL1 impairs release of neurotrophic extracellular vesicles by microglia.
Sommer, Christian and Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751
[Dataset]
14 September 2025
Phosphoproteomics for studying signaling pathways evoked by hormones of the renin-angiotensin system: a source of untapped potential.
Souza-Silva, I.M. ORCID: https://orcid.org/0000-0002-6140-3503, Carregari, V.C. ORCID: https://orcid.org/0000-0001-6863-1333, Steckelings, U.M. ORCID: https://orcid.org/0000-0002-5430-4275 and Verano-Braga, T. ORCID: https://orcid.org/0000-0002-7083-2588
Acta Physiologica 241
(2): e14280.
February 2025
LINNAEUS: simultaneous single-cell lineage tracing and cell type identification.
Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Methods in Molecular Biology 2886
: 243-263.
3 January 2025
CNSistent integration and feature extraction from somatic copy number profiles.
Streck, Adam ORCID: https://orcid.org/0000-0002-7302-0147 and Schwarz, Roland F. ORCID: https://orcid.org/0000-0001-9155-4268
GigaScience 14
: giaf104.
13 September 2025
Therapy adherence after interdisciplinary tumour board discussion is associated with improved outcome in soft tissue sarcoma: a Charité Comprehensive Cancer Centre analysis.
Strönisch, A. ORCID: https://orcid.org/0000-0002-0961-4602, Rau, D., Wittenberg, S., Kaul, D., Koulaxouzidis, G., Öllinger, R., von Laffert, M., Jarosch, A., Schäfer, F., Keilholz, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Märdian, S., Striefler, J. and Flörcken, A.
International Journal of Cancer 156
(4): 802-816.
15 February 2025
hnRNPA2B1 drives colorectal cancer progression via the circCDYL/EIF4A3/PHF8 axis.
Sun, Y.K., Wang, J.F., Sun, X.W. and Zhang, M. ORCID: https://orcid.org/0009-0002-8397-9826
Kaohsiung Journal of Medical Sciences 41
(3): e12943.
March 2025
Antibiotic-perturbed microbiota and the role of probiotics.
Szajewska, H. ORCID: https://orcid.org/0000-0002-4596-2874, Scott, K.P. ORCID: https://orcid.org/0000-0002-4608-0013, de Meij, T., Forslund-Startceva, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Knight, R. ORCID: https://orcid.org/0000-0002-0975-9019, Koren, O. ORCID: https://orcid.org/0000-0002-7738-1337, Little, P., Johnston, B.C., Łukasik, J. ORCID: https://orcid.org/0000-0002-9385-857X, Suez, J. ORCID: https://orcid.org/0000-0003-3836-972X, Tancredi, D.J. and Sanders, M.E. ORCID: https://orcid.org/0000-0001-6321-3423
Nature Reviews Gastroenterology & Hepatology 22
(3): 155-172.
March 2025
DNA virus infections shape transposable elements activity in vitro and in vivo.
Tan, J., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Neugebauer, E., Pennisi, S., Schächtle, M.A., Lagisquet, J., Kuderna, A.K., Walter, S., Welker, I., Ensser, A., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Stamminger, T., Gramberg, T., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806 and Full, F.
bioRxiv
: 2024.04.18.589901v2.
30 June 2025
Pronounced impairment of B cell differentiation during bone regeneration in adult immune experienced mice.
Tchouto, M.N., Bucher, C.H., Mess, A.K., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Schmidt-Bleek, K., Duda, G.N., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Milek, M. ORCID: https://orcid.org/0000-0002-0803-8439
Frontiers in Immunology 16
: 1511902.
3 March 2025
Editorial overview: mathematical modeling of disease processes.
Thurley, Kevin and Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868
Current Opinion in Systems Biology 42
: 100554.
December 2025
Advanced disease and CD8(+) TEMRA cells predict severe infections in multiple myeloma.
Tranter, E., Busch, D., Heck, C., Blau, I.W., Nogai, A., Schiele, P., Meisel, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Frentsch, M. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 16
12 February 2025
Maternal smoking in early pregnancy disrupts placental function through syncytiotrophoblast and macrophage dysregulation.
Valdes, Daniela S. ORCID: https://orcid.org/0000-0002-1309-5147, Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799, Nonn, Olivia ORCID: https://orcid.org/0000-0001-6385-2866, Ulrich, Juliane, Forstner, Désirée ORCID: https://orcid.org/0000-0001-5451-7580, Haider, Sandra ORCID: https://orcid.org/0000-0003-2409-1317, Ressler, Miriam ORCID: https://orcid.org/0000-0002-8669-9451, Pignitter, Marc ORCID: https://orcid.org/0000-0002-5793-8572, Müller, Dominik N. ORCID: https://orcid.org/0000-0003-3650-5644, Dechend, Ralf ORCID: https://orcid.org/0000-0001-6636-3080, Gauster, Martin ORCID: https://orcid.org/0000-0003-0386-6857, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081 and Herse, Florian ORCID: https://orcid.org/0000-0002-9305-8134
bioRxiv
: 2025.07.10.664172.
15 July 2025
Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer.
Volkmar, M., Hoser, D., Lauenstein, C., Rebmann, J., Hotz-Wagenblatt, A., Rieger, J., Poschke, I. ORCID: https://orcid.org/0000-0002-4387-5566, Becker, J.P., Riemer, A.B., Sprick, M., Trumpp, A., Strobel, O., Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X and Offringa, R. ORCID: https://orcid.org/0000-0001-6310-1026
Journal for ImmunoTherapy of Cancer 13
(6): e011802.
June 2025
Ultra-high-scale cytometry-based cellular interaction mapping.
Vonficht, Dominik ORCID: https://orcid.org/0000-0002-5579-7083, Jopp-Saile, Lea ORCID: https://orcid.org/0000-0002-7032-3003, Yousefian, Schayan ORCID: https://orcid.org/0000-0003-0902-0369, Flore, Viktoria ORCID: https://orcid.org/0009-0001-3023-433X, Simó Vesperinas, Inés ORCID: https://orcid.org/0000-0001-8965-127X, Teuber, Ruth, Avanesyan, Bogdan ORCID: https://orcid.org/0009-0004-2547-6598, Luo, Yanjiang ORCID: https://orcid.org/0009-0003-0401-467X, Röthemeier, Caroline, Grünschläger, Florian ORCID: https://orcid.org/0000-0003-0021-6912, Fernandez-Vaquero, Mirian, Fregona, Vincent ORCID: https://orcid.org/0000-0003-4857-1737, Ordoñez-Rueda, Diana ORCID: https://orcid.org/0000-0002-8387-6707, Schmalbrock, Laura K. ORCID: https://orcid.org/0000-0002-6080-6175, Deininger, Luca ORCID: https://orcid.org/0009-0005-5125-6422, Yamachui Sitcheu, Angelo Jovin ORCID: https://orcid.org/0009-0002-9384-6496, Gu, Zuguang, Funk, Maja C. ORCID: https://orcid.org/0000-0002-6007-1164, Mikut, Ralf ORCID: https://orcid.org/0000-0001-9100-5496, Heikenwälder, Mathias, Eggert, Angelika, von Stackelberg, Arend, Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673, Krönke, Jan, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Trumpp, Andreas, Hegazy, Ahmed N., Eckert, Cornelia ORCID: https://orcid.org/0000-0003-1039-2872, Hübschmann, Daniel ORCID: https://orcid.org/0000-0002-6041-7049 and Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051
Nature Methods 22
(9): 1887-1899.
September 2025
Ultra-high scale cytometry-based cellular interaction mapping - Data repository.
Vonficht, Dominik ORCID: https://orcid.org/0000-0002-5579-7083, Jopp-Saile, Lea ORCID: https://orcid.org/0000-0002-7032-3003, Yousefian, Schayan ORCID: https://orcid.org/0000-0003-0902-0369, Flore, Viktoria ORCID: https://orcid.org/0009-0001-3023-433X, Simó Vesperinas, Inés ORCID: https://orcid.org/0000-0001-8965-127X, Teuber, Ruth, Avanesyan, Bogdan ORCID: https://orcid.org/0009-0004-2547-6598, Luo, Yanjiang ORCID: https://orcid.org/0009-0003-0401-467X, Röthemeier, Caroline, Grünschläger, Florian ORCID: https://orcid.org/0000-0003-0021-6912, Fernandez-Vaquero, Mirian, Fregona, Vincent ORCID: https://orcid.org/0000-0003-4857-1737, Ordoñez-Rueda, Diana ORCID: https://orcid.org/0000-0002-8387-6707, Schmalbrock, Laura K. ORCID: https://orcid.org/0000-0002-6080-6175, Deininger, Luca ORCID: https://orcid.org/0009-0005-5125-6422, Yamachui Sitcheu, Angelo Jovin ORCID: https://orcid.org/0009-0002-9384-6496, Gu, Zuguang, Funk, Maja C. ORCID: https://orcid.org/0000-0002-6007-1164, Mikut, Ralf ORCID: https://orcid.org/0000-0001-9100-5496, Heikenwälder, Mathias, Eggert, Angelika, von Stackelberg, Arend, Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673, Krönke, Jan, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Trumpp, Andreas, Hegazy, Ahmed N., Eckert, Cornelia ORCID: https://orcid.org/0000-0003-1039-2872, Hübschmann, Daniel ORCID: https://orcid.org/0000-0002-6041-7049 and Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051
[Dataset]
16 January 2025
Acute promyelocytic leukemia: long-term outcomes from the HARMONY project.
Voso, M.T., Guarnera, L., Lehmann, S., Döhner, K., Döhner, H., Platzbecker, U., Russell, N.H., Dillon, R.J., Thomas, I., Ossenkoppele, G.J., Haferlach, T., Vignetti, M., La Sala, E., Piciocchi, A., Fazi, P., Villaverde Ramiro, Á., Tur Giménez, L., Gurnari, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Hernandez, J.M.
Blood 145
(2): 234-243.
9 January 2025
Impact of cellular composition and T-cell senescence of mononuclear cell concentrates on the manufacturing process of chimeric antigen receptor (CAR) T-cells.
Vučinić, Vladan ORCID: https://orcid.org/0000-0002-8398-285X, Tumewu, Theresa, Brückner, Mandy, Kirchberg, Janine, Jentzsch, Madlen, Buhmann, Raymund, Remane, Yvonne, Hoffmann, Sandra, Ramdohr, Florian, Merz, Maximilian, Metzeler, Klaus H., Schwind, Sebastian, Herling, Carmen, Krauß, Simon M. ORCID: https://orcid.org/0009-0009-8514-5500, Herling, Marco, Franke, Georg-Nikolaus, Grieb, Nora, Stachel, Georg, Janz, Martin ORCID: https://orcid.org/0000-0002-1127-0044, Penack, Olaf, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Cross, Michael, Henschler, Reinhard ORCID: https://orcid.org/0000-0002-5895-4259, Bach, Enrica and Platzbecker, Uwe
Transfusion 65
(9): 1650-1661.
September 2025
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation [ATAC-seq].
Vučićević, D. ORCID: https://orcid.org/0000-0002-1162-6709, Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Lopez Zepeda, L.S. ORCID: https://orcid.org/0000-0001-9764-0984, Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, Hirsekorn, A., Bilić, I. ORCID: https://orcid.org/0000-0002-2730-1634, Kastelić, N., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
[Dataset]
11 September 2025
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation [bulkCRISPR-screen].
Vučićević, D. ORCID: https://orcid.org/0000-0002-1162-6709, Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Lopez Zepeda, L.S. ORCID: https://orcid.org/0000-0001-9764-0984, Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, Hirsekorn, A., Bilić, I. ORCID: https://orcid.org/0000-0002-2730-1634, Kastelić, N., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
[Dataset]
11 September 2025
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation [TESLA-seq].
Vučićević, Dubravka ORCID: https://orcid.org/0000-0002-1162-6709, Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Lopez Zepeda, L.S. ORCID: https://orcid.org/0000-0001-9764-0984, Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, Hirsekorn, A., Bilić, I. ORCID: https://orcid.org/0000-0002-2730-1634, Kastelić, N., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
[Dataset]
11 September 2025
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation [NuCaptureC].
Vučićević, Dubravka ORCID: https://orcid.org/0000-0002-1162-6709, Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Lopez Zepeda, L.S. ORCID: https://orcid.org/0000-0001-9764-0984, Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, Hirsekorn, A., Bilić, I. ORCID: https://orcid.org/0000-0002-2730-1634, Kastelić, N., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
[Dataset]
1 June 2025
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation [Chromatin RNA-seq].
Vučićević, Dubravka ORCID: https://orcid.org/0000-0002-1162-6709, Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Lopez-Zepeda, L.S. ORCID: https://orcid.org/0000-0001-9764-0984, Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, Hirsekorn, A., Bilić, I. ORCID: https://orcid.org/0000-0002-2730-1634, Kastelić, N., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
[Dataset]
11 September 2025
Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation.
Vučićević, Dubravka ORCID: https://orcid.org/0000-0002-1162-6709, Hsu, Che-Wei ORCID: https://orcid.org/0000-0003-3709-9748, Lopez Zepeda, Lorena Sofia ORCID: https://orcid.org/0000-0001-9764-0984, Burkert, Martin ORCID: https://orcid.org/0000-0002-6721-9985, Hirsekorn, Antje, Bilić, Ilija ORCID: https://orcid.org/0000-0002-2730-1634, Kastelić, Nicolai, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Lacadie, Scott Allen ORCID: https://orcid.org/0000-0002-0893-5340 and Ohler, Uwe ORCID: https://orcid.org/0000-0002-0881-3116
Cell Genomics 5
(10): 100984.
8 October 2025
Recombination junctions from antibody isotype switching classify immune and DNA repair dysfunction.
Vázquez García, Clara ORCID: https://orcid.org/0000-0003-4583-7616, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Keller, Baerbel, Lebedin, Mikhail ORCID: https://orcid.org/0000-0002-3877-7195, Ratswohl, Christoph ORCID: https://orcid.org/0000-0001-5413-0730, Abolhassani, Hassan ORCID: https://orcid.org/0000-0002-4838-0407, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Di Virgilio, Michela ORCID: https://orcid.org/0000-0001-5189-0793, Mathas, Stephan ORCID: https://orcid.org/0000-0001-9626-1413, Speiser, Dorothee, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Pan-Hammarström, Qiang ORCID: https://orcid.org/0000-0003-1990-8804, Warnatz, Klaus ORCID: https://orcid.org/0000-0002-1172-865X and de la Rosa, Kathrin ORCID: https://orcid.org/0000-0003-4809-3157
Nature Communications 16
(1): 11331.
19 December 2025
Cross-platform clinical proteomics using the Charité open standard for plasma proteomics (OSPP).
Wang, Ziyue ORCID: https://orcid.org/0000-0002-4121-4799, Farztdinov, Vadim, Sinn, Ludwig Roman, Tober-Lau, Pinkus ORCID: https://orcid.org/0000-0002-9148-3663, Ludwig, Daniela, Freiwald, Anja, Amari, Fatma, Textoris-Taube, Kathrin, Niewienda, Agathe, Welter, Anna Sophie ORCID: https://orcid.org/0009-0003-9846-3889, Wei, Alan An Jung ORCID: https://orcid.org/0000-0003-4255-9470, Luckau, Luise, Kurth, Florian ORCID: https://orcid.org/0000-0002-3807-473X, Selbach, Matthias ORCID: https://orcid.org/0000-0003-2454-8751, Hartl, Johannes ORCID: https://orcid.org/0000-0001-8470-5355, Mülleder, Michael ORCID: https://orcid.org/0000-0001-9792-3861 and Ralser, Markus ORCID: https://orcid.org/0000-0001-9535-7413
Nature Communications 16
(1): 11377.
23 December 2025
Clinical characteristics and outcomes in leptomeningeal disease with or without brain metastasis: insights from an explorative data analysis of the Charité LMD registry.
Wasilewski, D., Eitner, C., Ates, R., Murad, S., Shaked, Z., Steinle, J.A., Wetzel-Yalelis, A., Sargut, T.A., Rösler, J., Samman, M.A., Truckenmüller, P., Mertens, R., Kroneberg, D., Kowski, A., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Capper, D., Ehret, F., Roohani, S., Frost, N., Nawabi, J., Onken, J., Schlaak, M., Blohmer, J.U., Pelzer, U., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Sehouli, J., Vajkoczy, P., Keilholz, U. and Misch, M.
Journal of Neuro-Oncology 175
(3): 943-965.
December 2025
The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells.
Weaver, M.R., Shkoruta, D., Pellegatta, M., Berti, C., Palmisano, M., Ferguson, S., Hurley, E., French, J., Patel, S., Belin, S., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Paul, F.E. ORCID: https://orcid.org/0000-0001-5181-3122, Sim, F., Poitelon, Y. and Feltri, M.L.
Cell Reports 44
(3): 115401.
6 March 2025
The prognostic role of frailty and its recognition with simple FRAIL and fried frailty questionnaires in advanced cancer patients.
Weinländer, Pia, Hadzibegovic, Sara, Porthun, Jan, Kretzler, Lucie, Evertz, Ruben, Lena, Alessia, Lück, Laura-Carina, Hella, Jonathan L, Wilkenshoff, Ursula, Stroux, Andrea, Keramida, Kalliopi, Letsch, Anne, Modest, Dominik Paul, Bullinger, Lars ORCID: https://orcid.org/0000-0002-5890-5510, Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958, Karakas, Mahir, Abdelwahed, Youssef S., Attanasio, Philipp, Rauch, Ursula, Skurk, Carsten, Doehner, Wolfram, Landmesser, Ulf, von Haehling, Stephan and Anker, Markus S.
Journal of Cachexia Sarcopenia and Muscle 16
(5): e70076.
October 2025
Guiding clinical management of patients with CNS lymphomas by minimal-invasive detection of ctDNA in cerebrospinal fluid.
Weinschenk, S, Philipp, U, Kuehn, J C, Mueller, K, Fauser, J, Boeckle, D, Gebhard, I, Hinz, M, Neidert, N, Bleul, S, Lauer, E M, Mutter, J A, Alig, S K, Kurtz, D M, Finke, J, Marks, R, Diehn, M, Alizadeh, A A, Reinacher, P C, Wehrle, J, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Wolf, D, Kocher, F, Chapuy, B, Beck, J, Prinz, M, von Baumgarten, L, Schorb, E, Duyster, J and Scherer, F
Leukemia 39
(5): 1265-1268.
May 2025
Cryo-EM structure of Legionella effector SdeC (3D flexible refinement).
Weng, T.H., Misra, M., Chen, W., Safarian, S., Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Dikic, I.
[Dataset]
18 June 2025
Cryo-EM structure of Legionella effector SdeC (3D flexible refinement).
Weng, T.H., Misra, M., Chen, W., Safarian, S., Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Dikic, I.
[Dataset]
4 June 2025
Cryo-EM structure of Legionella effector SdeC (PDE-mART domain).
Weng, T.H., Misra, M., Chen, W., Safarian, S., Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Dikic, I.
[Dataset]
4 June 2025
Cryo-EM structure of Legionella effector SdeC (PDE-mART domain).
Weng, T.H., Misra, M., Chen, W., Safarian, S., Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Dikic, I.
[Dataset]
4 June 2025
Persistent abdominal pain and diarrhea after appendectomy-Crohn's disease versus intestinal tuberculosis.
Wizenty, J., Maibier, M. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
JGH Open 9
(4): e70157.
April 2025
Helicobacter pylori, microbiota and gastric cancer - principles of microorganism-driven carcinogenesis.
Wizenty, J. ORCID: https://orcid.org/0000-0003-4261-0416 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Reviews Gastroenterology & Hepatology 22
(5): 296-313.
May 2025
Informationsschatz aus Umweltproben [Treasure trove of information from environmental samples].
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
BIOspektrum 31
(1): 59-62.
February 2025
Spatial multiomics of acute myocardial infarction reveals immune cell infiltration through the endocardium.
Wünnemann, Florian, Sicklinger, Florian ORCID: https://orcid.org/0009-0004-6707-1695, Bestak, Kresimir ORCID: https://orcid.org/0009-0009-8245-9846, Nimo, Jose ORCID: https://orcid.org/0000-0002-1565-7799, Thiemann, Tobias ORCID: https://orcid.org/0009-0003-7284-2127, Amrute, Junedh M ORCID: https://orcid.org/0000-0002-6851-0168, Nordbeck, Mathias ORCID: https://orcid.org/0009-0003-0392-6685, Hartmann, Niklas ORCID: https://orcid.org/0009-0009-1799-7162, Ibarra-Arellano, Miguel A ORCID: https://orcid.org/0000-0001-8411-4854, Tanevski, Jovan ORCID: https://orcid.org/0000-0001-7177-1003, Chazotte, Margot ORCID: https://orcid.org/0009-0007-4901-5173, Heine, Clara ORCID: https://orcid.org/0009-0001-3506-2119, Frey, Norbert, Lavine, Kory J ORCID: https://orcid.org/0000-0003-1948-9945, Coscia, Fabian ORCID: https://orcid.org/0000-0002-2244-5081, Saez-Rodriguez, Julio ORCID: https://orcid.org/0000-0002-8552-8976, Leuschner, Florian ORCID: https://orcid.org/0000-0003-1157-474X and Schapiro, Denis ORCID: https://orcid.org/0000-0002-9391-5722
Nature Cardiovascular Research 4
(10): 1345-1362.
October 2025
Iterative Bleaching Extends Multiplexity (IBEX) Knowledge-Base.
Yaniv, Ziv ORCID: https://orcid.org/0000-0003-0315-7727, Anidi, Ifeanyichukwu ORCID: https://orcid.org/0000-0002-2692-1225, Arakkal, Leanne ORCID: https://orcid.org/0000-0001-9189-7172, Arroyo-Mejias, Armando ORCID: https://orcid.org/0000-0002-0835-911X, Beuschel, Rebecca T. ORCID: https://orcid.org/0000-0002-3882-457X, Börner, Katy ORCID: https://orcid.org/0000-0002-3321-6137, Chu, Colin J. ORCID: https://orcid.org/0000-0003-2088-8310, Clark, Beatrice ORCID: https://orcid.org/0009-0003-9817-7874, Clatworthy, Menna ORCID: https://orcid.org/0000-0002-3340-9828, Colautti, Jake ORCID: https://orcid.org/0000-0002-1461-0999, Croteau, Joshua ORCID: https://orcid.org/0000-0002-8142-0482, Denha, Saven ORCID: https://orcid.org/0009-0004-8162-409X, Dever, Rose ORCID: https://orcid.org/0009-0004-2746-8743, Dutra, Walderez ORCID: https://orcid.org/0000-0002-7586-9996, Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534, Fullam, Spencer ORCID: https://orcid.org/0000-0001-9012-3802, Gerner, Michael ORCID: https://orcid.org/0000-0001-5406-8308, Gola, Anita ORCID: https://orcid.org/0000-0003-1431-1398, Gollob, Kenneth J. ORCID: https://orcid.org/0000-0003-4184-3867, Ichise, Hiroshi ORCID: https://orcid.org/0000-0002-5187-810X, Jing, Zhixin ORCID: https://orcid.org/0000-0003-1118-7432, Jonigk, Danny ORCID: https://orcid.org/0000-0002-5251-2281, Kandov, Evelyn ORCID: https://orcid.org/0000-0001-7071-9916, Kastenmüller, Wolfgang ORCID: https://orcid.org/0000-0002-3835-1485, Koenig, Joshua F.E. ORCID: https://orcid.org/0000-0002-8909-5039, Kortekaas, Rosa K. ORCID: https://orcid.org/0000-0002-8728-1735, Kothurkar, Aanandita ORCID: https://orcid.org/0009-0000-2047-4228, Krzywańska, Aleksandra ORCID: https://orcid.org/0009-0006-4918-5749, Lamborn, Ian ORCID: https://orcid.org/0009-0006-1490-3667, Lin, Yuri ORCID: https://orcid.org/0009-0006-9784-2694, Luz, Jean Carlos Dos Santos ORCID: https://orcid.org/0000-0001-5088-7808, Makranz, Chen ORCID: https://orcid.org/0000-0002-6944-6997, McNamara, George ORCID: https://orcid.org/0000-0003-4155-0976, Moriarty, Ryan V. ORCID: https://orcid.org/0000-0001-7100-1906, Murakami Olyntho, Vitoria ORCID: https://orcid.org/0000-0003-2634-6838, Padhan, Kartika ORCID: https://orcid.org/0000-0001-9561-4256, Richoz, Nathan ORCID: https://orcid.org/0000-0002-7422-3237, Shang, Wanjing ORCID: https://orcid.org/0009-0007-0646-7946, Shi, Lihong ORCID: https://orcid.org/0000-0002-6604-2065, Shih, Rochelle ORCID: https://orcid.org/0000-0002-3218-4479, Speranza, Emily ORCID: https://orcid.org/0000-0003-0666-4804, Teichmann, Sarah ORCID: https://orcid.org/0000-0002-6294-6366, Veres, Tibor Z. ORCID: https://orcid.org/0000-0002-6980-8900, Vierhout, Megan ORCID: https://orcid.org/0000-0001-5813-2581, Wachter, Brianna ORCID: https://orcid.org/0000-0002-2950-2683, Wade-Vallance, Adam K. ORCID: https://orcid.org/0000-0002-6863-1461, Williams, Margaret ORCID: https://orcid.org/0000-0003-3697-5726, Zangger, Nathan ORCID: https://orcid.org/0000-0003-1130-1899, Germain, Ronald N. ORCID: https://orcid.org/0000-0003-1495-9143 and Radtke, Andrea J. ORCID: https://orcid.org/0000-0003-4379-8967
[Dataset]
26 September 2025
Selective depletion of cancer cells with extrachromosomal DNA via lentiviral infection.
Yi, Eunhee, Gujar, Amit D., Zhao, Dacheng, Suina, Kentaro, Jin, Xue, Pardon, Katharina, Yu, Qinghao ORCID: https://orcid.org/0000-0002-2151-9624, Kagermazova, Larisa, Korsah, Emmanuel E., Dusseau, Noah A., Boeke, Jef D., Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X and Verhaak, Roel G.W.
Cancer Research Communications 5
(8): 1458-1465.
August 2025
Insights into therapeutic discovery through the Kelch domain structure of Keap1 at ambient temperature.
Yilmaz, M. ORCID: https://orcid.org/0000-0003-3346-2781, Sever, B. ORCID: https://orcid.org/0000-0003-4847-9711, Kutlu, Y. ORCID: https://orcid.org/0000-0001-5917-2550, Gül, M. ORCID: https://orcid.org/0000-0001-5513-1866, Okuducu, C. ORCID: https://orcid.org/0009-0008-8976-0204, Tavli, S. ORCID: https://orcid.org/0000-0001-9362-8013, Otsuka, M. ORCID: https://orcid.org/0000-0002-2968-3939, Fujita, M. ORCID: https://orcid.org/0000-0001-6705-4052, Haliloğlu, T. ORCID: https://orcid.org/0000-0002-1279-5803, Çiftçi, H. ORCID: https://orcid.org/0000-0002-9796-7669 and Demirci, H. ORCID: https://orcid.org/0000-0002-9135-5397
Turkish Journal of Biology 49
(3): 247-260.
26 June 2025
Topology control by a conserved cysteine pair in the OMM-protein CCDC127 enables MICOS interaction.
Zarges, Christine, Schepsky, Pauline, Rothemann, Robin Alexander, Bock-Bierbaum, Tobias ORCID: https://orcid.org/0000-0003-0843-2716, von der Malsburg, Alexander, Baumann, Linda, Trifunovic, Aleksandra ORCID: https://orcid.org/0000-0002-5472-3517, Daumke, Oliver ORCID: https://orcid.org/0000-0002-6190-1414, van der Laan, Martin ORCID: https://orcid.org/0000-0003-0789-9912, von der Malsburg, Karina and Riemer, Jan ORCID: https://orcid.org/0000-0002-7574-8457
bioRxiv
: 2025.12.12.693940.
15 December 2025
Everolimus with or without mycophenolate mofetil for graft-versus-host disease prophylaxis after hematopoietic stem cell transplantation in children with acute kidney injury: a single-center retrospective Analysis.
Zirngibl, F., Gebert, P., Materne, B., Launspach, M., Künkele, A., Hundsdoerfer, P., Cyrull, S., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Kühl, J.S., Eggert, A., Lang, P., Oevermann, L., von Stackelberg, A. and Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201
Transplantation and Cellular Therapy 31
(4): 257-257.
April 2025
Total lesion glycolysis of primary tumor and lymphnodes is a strong predictor for development of distant metastases in oropharyngeal carcinoma patients with independent validation in automatically delineated lesions.
Zschaeck, S. ORCID: https://orcid.org/0000-0003-3109-0662, Hajiyianni, M., Hausmann, P., Nikulin, P., Kukuk, E., Furth, C., Cegla, P., Lombardo, E., Kazmierska, J., Holzgreve, A., Strouthos, I., Stromberger, C., Belka, C., Baumann, M., Krause, M., Landry, G., Cholewinski, W., Kotzerke, J., Zips, D., Van den Hoff, J. and Hofheinz, F.
Cancer Imaging 25
(1): 18.
21 February 2025
New MERS-CoV Vaccine.
Max Delbrueck Centrum fuer Molekulare in der Helmholtz Gemeinschaft.
EP-4499140-A1.
5 February 2025
Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells.
van Bentum, M., Klinger, B. ORCID: https://orcid.org/0000-0003-0242-1506, Sieber, A. ORCID: https://orcid.org/0000-0001-6588-8547, Naghiloo, S. ORCID: https://orcid.org/0009-0001-7354-2930, Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Lehmann, N. ORCID: https://orcid.org/0009-0006-2588-2283, Haji, M., Niquet, S., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Nature Communications 16
(1): 4884.
27 May 2025
Neuromuscular dysfunction in patient-derived FUS(R244RR)-ALS iPSC model via axonal downregulation of neuromuscular junction proteins.
von Kügelgen, N. ORCID: https://orcid.org/0000-0001-8116-9032, Ludwik, K.A. ORCID: https://orcid.org/0000-0002-9436-7270, Mendonsa, S. ORCID: https://orcid.org/0000-0001-9814-6662, Römer, C., Becher, E., Breimann, L. ORCID: https://orcid.org/0000-0001-7702-5749, Strauch, M., Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, Mongellaz, S., Zuckerman, B. ORCID: https://orcid.org/0000-0002-6216-011X, Efendic, F. ORCID: https://orcid.org/0000-0002-8462-0690, Grexa, N., Oliveras-Martinez, A. ORCID: https://orcid.org/0000-0002-5880-5245, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, La Bella, V., Ulitsky, I. ORCID: https://orcid.org/0000-0003-0555-6561 and Chekulaeva, M. ORCID: https://orcid.org/0000-0002-6868-7887
NAR Molecular Medicine 2
(2): ugaf005.
April 2025
Faecal cytolysin is associated with worse survival in patients with primary sclerosing cholangitis.
Özdirik, B., Berger, H., Tonetti, F.R., Cabré, N., Treichel, N., Clavel, T., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Schnabl, B. ORCID: https://orcid.org/0000-0002-6281-825X
Liver International 45
(4): e16181.
April 2025
2024
Deciphering the impact of genomic variation on function.
Nature 633
(8028): 47-57.
5 September 2024
Temperature dependent sex determination in the turtle Trachemys scripta.
[Dataset]
1 July 2024
Temperature dependent sex determination in the turtle Trachemys scripta.
Acemel, R.D. ORCID: https://orcid.org/0000-0003-4120-0140, Tezak, B., Chung, W.Y., Webber, C., Mota, I., Hurtado, A. ORCID: https://orcid.org/0000-0001-6267-704X, Capel, B. and Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X
[Dataset]
30 December 2024
Genetic determinants of micronucleus formation in vivo.
Adams, D.J., Barlas, B., McIntyre, R.E., Salguero, I., van der Weyden, L., Barros, A., Vicente, J.R., Karimpour, N., Haider, A., Ranzani, M., Turner, G., Thompson, N.A., Harle, V., Olvera-León, R., Robles-Espinoza, C.D., Speak, A.O., Geisler, N., Weninger, W.J., Geyer, S.H., Hewinson, J., Karp, N.A., Fu, B., Yang, F., Kozik, Z., Choudhary, J., Yu, L., van Ruiten, M.S., Rowland, B.D., Lelliott, C.J., Del Castillo Velasco-Herrera, M., Verstraten, R., Bruckner, L., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Rooimans, M.A., de Lange, J., Mohun, T.J., Arends, M.J., Kentistou, K.A., Coelho, P.A., Zhao, Y., Zecchini, H., Perry, J.R.B., Jackson, S.P. and Balmus, G.
Nature 627
(8002): 130-136.
7 March 2024
Additional file 10 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 11 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 12 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 13 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 14 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 15 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 16 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 17 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 18 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 19 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 20 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 21 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Additional file 9 of Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin.
Al-Diab, Ola, Sünkel, Christin ORCID: https://orcid.org/0000-0002-5326-6043, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Catar, Rusan Ali, Ashraf, Muhammad Imtiaz, Zhao, Hongfan, Wang, Pinchao, Rinschen, Markus M., Fritsche-Guenther, Raphaela ORCID: https://orcid.org/0000-0002-6965-0226, Grahammer, Florian, Bachmann, Sebastian, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Kirwan, Jennifer A. ORCID: https://orcid.org/0000-0002-5423-1651, Rajewsky, Nikolaus ORCID: https://orcid.org/0000-0002-4785-4332, Huber, Tobias B., Gürgen, Dennis and Kusch, Angelika ORCID: https://orcid.org/0000-0002-6666-7081
[Dataset]
2 October 2024
Teclistamab-induced remission in refractory systemic lupus erythematosus.
Alexander, T. ORCID: https://orcid.org/0000-0003-1193-0097, Krönke, J., Cheng, Q., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Krönke, G.
New England Journal of Medicine 391
(9): 864-866.
5 September 2024
CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition.
Andreu-Saumell, I. ORCID: https://orcid.org/0009-0006-8897-0846, Rodriguez-Garcia, A. ORCID: https://orcid.org/0000-0003-0906-1793, Mühlgrabner, V., Gimenez-Alejandre, M., Marzal, B., Castellsagué, J., Brasó-Maristany, F. ORCID: https://orcid.org/0000-0001-5440-9643, Calderon, H. ORCID: https://orcid.org/0000-0002-8902-4302, Angelats, L., Colell, S. ORCID: https://orcid.org/0000-0002-2132-2856, Nuding, M., Soria-Castellano, M. ORCID: https://orcid.org/0000-0002-0746-417X, Barbao, P. ORCID: https://orcid.org/0000-0001-7139-4420, Prat, A. ORCID: https://orcid.org/0000-0003-2377-540X, Urbano-Ispizua, A., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Guedan, S. ORCID: https://orcid.org/0000-0002-9605-0760
Nature Communications 15
(1): 3552.
26 April 2024
Dynamics of clonal hematopoiesis under DNA-damaging treatment in patients with ovarian cancer.
Arends, C.M. ORCID: https://orcid.org/0000-0003-4417-4750, Kopp, K., Hablesreiter, R. ORCID: https://orcid.org/0000-0002-4586-932X, Estrada, N., Christen, F. ORCID: https://orcid.org/0000-0001-8868-2533, Moll, U.M., Zeillinger, R., Schmitt, W.D. ORCID: https://orcid.org/0000-0002-7870-138X, Sehouli, J., Kulbe, H., Fleischmann, M., Ray-Coquard, I., Zeimet, A., Raspagliesi, F., Zamagni, C., Vergote, I., Lorusso, D., Concin, N., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Braicu, E.I. and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 38
(6): 1378-1389.
June 2024
In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia.
Bakina, O. ORCID: https://orcid.org/0000-0002-3486-9906, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Mitic, N. ORCID: https://orcid.org/0000-0003-0141-1293, Vidal, R.O. ORCID: https://orcid.org/0000-0003-4217-2014, Obrusnik, T., Sai, S. ORCID: https://orcid.org/0000-0001-6865-341X, Nolte, C. ORCID: https://orcid.org/0000-0001-5398-3440, Semtner, M. ORCID: https://orcid.org/0000-0001-9379-9023 and Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291
PLoS ONE 19
(7): e0302376.
11 July 2024
Extraembryonic gut endoderm cells undergo programmed cell death during development.
Batki, J. ORCID: https://orcid.org/0000-0002-1797-793X, Hetzel, S. ORCID: https://orcid.org/0000-0002-4783-3814, Schifferl, D. ORCID: https://orcid.org/0000-0003-3507-5734, Bolondi, A. ORCID: https://orcid.org/0000-0002-1096-9435, Walther, M., Wittler, L., Grosswendt, S. ORCID: https://orcid.org/0000-0001-7722-2937, Herrmann, B.G. and Meissner, A. ORCID: https://orcid.org/0000-0001-8646-7469
Nature Cell Biology 26
(6): 868-877.
June 2024
Novel human neurodevelopmental and neurodegenerative disease associated with IRF2BPL gene variants-mechanisms and therapeutic avenues.
Bauersachs, D., Bomholtz, L., Del Ray Mateos, S., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803 and Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072
Frontiers in Neuroscience 18
: 1426177.
6 June 2024
HoVer-NeXt: a fast nuclei segmentation and classification pipeline for next generation histopathology.
Baumann, E., Dislich, B., Rumberger, J.L. ORCID: https://orcid.org/0000-0002-7225-7011, Nagtegaal, I.D., Martínez, M.R. and Zlobec, I.
In: 7th International Conference on Medical Imaging with Deep Learning, 03-05 Jul 2024, Paris, France.
2024
Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022.
Baumgartner, F. ORCID: https://orcid.org/0000-0003-0768-1956, Baer, C., Bamopoulos, S.A. ORCID: https://orcid.org/0000-0002-5997-7735, Ayoub, E. ORCID: https://orcid.org/0000-0003-1321-0114, Truger, M., Meggendorfer, M., Lenk, M., Hoermann, G., Hutter, S. ORCID: https://orcid.org/0000-0003-2432-8898, Müller, H., Walter, W. ORCID: https://orcid.org/0000-0002-5083-9838, Mueller, M.L., Nadarajah, Ni., Blombery, P., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Kern, W., Haferlach, C. and Haferlach, T.
Blood 143
(12): 1139-1156.
21 March 2024
Activation of gp130 signaling in T cells drives T(H)17-mediated multi-organ autoimmunity.
Baumgartner, F. ORCID: https://orcid.org/0000-0003-0768-1956, Bamopoulos, S.A. ORCID: https://orcid.org/0000-0002-5997-7735, Faletti, L. ORCID: https://orcid.org/0000-0002-9213-2478, Hsiao, H.J., Holz, M. ORCID: https://orcid.org/0009-0002-1294-8205, Gonzalez-Menendez, I., Solé-Boldo, L. ORCID: https://orcid.org/0000-0002-6974-9066, Horne, A. ORCID: https://orcid.org/0000-0002-4209-4573, Gosavi, S., Özerdem, C. ORCID: https://orcid.org/0000-0001-6772-0422, Singh, N., Liebig, S. ORCID: https://orcid.org/0000-0002-5494-8476, Ramamoorthy, S. ORCID: https://orcid.org/0000-0003-3468-4247, Lehmann, M. ORCID: https://orcid.org/0000-0002-3786-7375, Demel, U. ORCID: https://orcid.org/0000-0002-6480-4185, Kühl, A.A. ORCID: https://orcid.org/0000-0003-2293-5387, Wartewig, T. ORCID: https://orcid.org/0000-0001-8699-1690, Ruland, J. ORCID: https://orcid.org/0000-0002-8381-3597, Wunderlich, F.T. ORCID: https://orcid.org/0000-0002-9209-3501, Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Rose-John, S. ORCID: https://orcid.org/0000-0002-7519-3279, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Quintanilla-Martinez, L., Feske, S., Ehl, S. ORCID: https://orcid.org/0000-0002-9265-2721, Glauben, R. ORCID: https://orcid.org/0000-0003-2889-2525 and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Science Signaling 17
(824): eadc9662.
20 February 2024
Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer.
Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Brame, Luca ORCID: https://orcid.org/0000-0001-5316-2992, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Fritsche-Guenther, R. ORCID: https://orcid.org/0000-0002-6965-0226, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Bhattacharya, A. ORCID: https://orcid.org/0000-0003-3733-7670, Rusu, M.C. ORCID: https://orcid.org/0000-0002-8369-3580, Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Dubois, F.P.B. ORCID: https://orcid.org/0000-0002-7654-6208, Köppke, J.K.C. ORCID: https://orcid.org/0000-0002-1293-7250, Proba, J. ORCID: https://orcid.org/0009-0006-8293-1248, Wittstruck, N. ORCID: https://orcid.org/0009-0000-4378-3226, Sidorova, O.A. ORCID: https://orcid.org/0009-0004-1459-1662, Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Xu, R. ORCID: https://orcid.org/0000-0002-5618-246X, Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Yu, Q. ORCID: https://orcid.org/0000-0002-2151-9624, Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Koche, R.P. ORCID: https://orcid.org/0000-0002-6820-5083, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Kirwan, J. ORCID: https://orcid.org/0000-0002-5423-1651, Hagemann, A.I. ORCID: https://orcid.org/0000-0001-5491-4607, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Cancer Discovery 14
(3): 492-507.
1 March 2024
Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry.
Ben Hamza, A., Welters, C., Stadler, S., Brüggemann, M., Dietze, K., Brauns, O., Brümmendorf, T.H., Winkler, T.H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Rosenberger, L., Leisegang, M., Kammertöns, T., Herr, W., Moosmann, A., Strobel, J., Hackstein, H., Dornmair, K., Beier, F. and Hansmann, L.
Blood 143
(14): 1365-1378.
4 April 2024
Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921, Wiedenmann, B. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Frontiers in Endocrinology 15
: 1331231.
17 April 2024
Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial.
Borchmann, P., Ferdinandus, J., Schneider, G., Moccia, A., Greil, R., Hertzberg, M., Schaub, V., Hüttmann, A., Keil, F., Dierlamm, J., Hänel, M., Novak, U., Meissner, J., Zimmermann, A., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Zijlstra, J.M., Fosså, A., Viardot, A., Hertenstein, B., Martin, S., Giri, P., Scholl, S., Topp, M.S., Jung, W., Vucinic, V., Beck, H.J., Kerkhoff, A., Unger, B., Rank, A., Schroers, R., zum Büschenfelde, C.M., de Wit, M., Trautmann-Grill, K., Kamper, P., Molin, D., Kreissl, S., Kaul, H., von Tresckow, B., Borchmann, S., Behringer, K., Fuchs, M., Rosenwald, A., Klapper, W., Eich, H.T., Baues, C., Zomas, A., Hallek, M., Dietlein, M., Kobe, C. and Diehl, V.
Lancet 404
(10450): 341-352.
27 July 2024
Single-cell time series analysis reveals the dynamics of HSPC response to inflammation.
Bouman, B.J. ORCID: https://orcid.org/0000-0003-1259-5040, Demerdash, Y., Sood, S., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Pilz, F., Itani, A.R. ORCID: https://orcid.org/0000-0001-7608-822X, Kuck, A., Marot-Lassauzaie, V. ORCID: https://orcid.org/0000-0002-8362-9634, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170 and Essers, M.A. ORCID: https://orcid.org/0000-0003-3117-1809
Life Science Alliance 7
(3): e202302309.
March 2024
Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia.
Bruedigam, C. ORCID: https://orcid.org/0000-0002-9580-1446, Porter, A.H., Song, A., Vroeg In de Wei, G., Stoll, T., Straube, J. ORCID: https://orcid.org/0000-0002-1748-0659, Cooper, L., Cheng, G., Kahl, V.F.S., Sobinoff, A.P., Ling, V.Y. ORCID: https://orcid.org/0000-0001-9757-1229, Jebaraj, B.M.C., Janardhanan, Y., Haldar, R., Bray, L.J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Heidel, F.H., Kennedy, G.A., Hill, M.M., Pickett, H.A., Abdel-Wahab, O. ORCID: https://orcid.org/0000-0002-3907-6171, Hartel, G. ORCID: https://orcid.org/0000-0002-5454-6450 and Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209
Nature Cancer 5
(1): 47-65.
January 2024
A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses.
Brunner, T.M. ORCID: https://orcid.org/0000-0002-5279-2391, Serve, S. ORCID: https://orcid.org/0000-0002-9839-7119, Marx, A.F., Fadejeva, J., Saikali, P. ORCID: https://orcid.org/0000-0002-4916-7376, Dzamukova, M. ORCID: https://orcid.org/0000-0002-2389-3222, Durán-Hernández, N. ORCID: https://orcid.org/0000-0003-4253-0387, Kommer, C., Heinrich, F. ORCID: https://orcid.org/0000-0001-6097-5422, Durek, P., Heinz, G.A. ORCID: https://orcid.org/0000-0002-9330-3689, Höfer, T. ORCID: https://orcid.org/0000-0003-3560-8780, Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Pinschewer, D.D. ORCID: https://orcid.org/0000-0002-1594-3189 and Löhning, M. ORCID: https://orcid.org/0000-0001-6382-7281
Nature Immunology 25
(2): 256-267.
February 2024
Making AML fly too close to the sun.
Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Krönke, J. ORCID: https://orcid.org/0000-0002-4649-0506
Blood 143
(15): 1438-1439.
11 April 2024
Copy-number dosage regulates telomere maintenance and disease-associated pathways in neuroblastoma.
Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Thiessen, N., Weber, C., Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Monti, R. ORCID: https://orcid.org/0000-0002-6354-8319, Dombrowe, V.M. ORCID: https://orcid.org/0000-0002-1466-1518, de Biase, M.S. ORCID: https://orcid.org/0000-0003-0383-5161, Kaufmann, T.L. ORCID: https://orcid.org/0000-0003-4374-1338, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Waszak, S.M., Eggert, A., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268
iScience 27
(10): 110918.
18 October 2024
Hyperphenylalaninemia and serotonin deficiency in Dnajc12-deficient mice.
Cao, Y. ORCID: https://orcid.org/0000-0003-0440-3977, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Milani, N. ORCID: https://orcid.org/0000-0001-7510-7986, Qadri, F. ORCID: https://orcid.org/0000-0002-8500-489X, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433
Communications Biology 7
(1): 1641.
18 December 2024
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish.
Cardeira-da-Silva, J. ORCID: https://orcid.org/0000-0003-3722-8810, Wang, Q., Sagvekar, P. ORCID: https://orcid.org/0000-0003-4420-3806, Mintcheva, J. ORCID: https://orcid.org/0000-0003-0793-6277, Latting, S., Günther, S. ORCID: https://orcid.org/0000-0002-5594-4549, Ramadass, R., Yekelchyk, M., Preussner, J., Looso, M., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Stainier, D.Y.R.
Nature Communications 15
(1): 3637.
29 April 2024
Proteomic signatures improve risk prediction for common and rare diseases.
Carrasco-Zanini, J. ORCID: https://orcid.org/0000-0002-3988-7505, Pietzner, M. ORCID: https://orcid.org/0000-0003-3437-9963, Davitte, J., Surendran, P., Croteau-Chonka, D.C. ORCID: https://orcid.org/0000-0003-3466-1846, Robins, C., Torralbo, A., Tomlinson, C. ORCID: https://orcid.org/0000-0002-0903-5395, Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Fitzpatrick, N., Ytsma, C. ORCID: https://orcid.org/0000-0002-8333-6428, Kanno, T., Gade, S., Freitag, D., Ziebell, F., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Denaxas, S., Betts, J.C., Wareham, N.J. ORCID: https://orcid.org/0000-0003-1422-2993, Hemingway, H. ORCID: https://orcid.org/0000-0003-2279-0624, Scott, R.A. ORCID: https://orcid.org/0000-0003-3634-3016 and Langenberg, C. ORCID: https://orcid.org/0000-0002-5017-7344
Nature Medicine 30
(9): 2489-2498.
September 2024
SRRM2 splicing factor modulates cell fate in early development.
Carvalho, S. ORCID: https://orcid.org/0000-0001-6436-205X, Zea-Redondo, L. ORCID: https://orcid.org/0000-0001-9064-9126, Tang, T.C.C. ORCID: https://orcid.org/0000-0002-4263-1447, Stachel-Braum, P. ORCID: https://orcid.org/0009-0006-4622-8838, Miller, D. ORCID: https://orcid.org/0000-0001-9852-677X, Caldas, P., Kukalev, A. ORCID: https://orcid.org/0000-0001-5847-3773, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Grosswendt, S. ORCID: https://orcid.org/0000-0001-7722-2937, Grosso, A.R. and Pombo, A. ORCID: https://orcid.org/0000-0002-7493-6288
Biology Open 13
(4): bio060415.
April 2024
Management of busulfan-induced lung injury in pediatric patients with high-risk neuroblastoma.
Castelli, S. ORCID: https://orcid.org/0000-0001-7660-5354, Thorwarth, A., van Schewick, C., Wendt, A. ORCID: https://orcid.org/0000-0002-8984-6111, Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Lodrini, M. ORCID: https://orcid.org/0000-0003-4434-529X, Veldhoen, S. ORCID: https://orcid.org/0000-0002-3585-5442, Gratopp, A. ORCID: https://orcid.org/0000-0001-5879-2918, Mall, M.A. ORCID: https://orcid.org/0000-0002-4057-2199, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184 and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Journal of Clinical Medicine 13
(19): 5995.
8 October 2024
Compound-SNE: comparative alignment of t-SNEs for multiple single-cell omics data visualization.
Cess, C.G. ORCID: https://orcid.org/0000-0002-1398-2846 and Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170
Bioinformatics 40
(7): btae471.
July 2024
Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system.
Chen, X.T. ORCID: https://orcid.org/0000-0002-5614-1406, Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Gavvovidis, I. ORCID: https://orcid.org/0000-0001-5644-9788, Pollack, S.M., Lorenz, F.K.M. ORCID: https://orcid.org/0000-0001-7826-0839, Schumacher, T.N., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Frontiers in Immunology 15
: 1524629.
24 December 2024
LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression.
Chen, W., Wang, F., Yu, X., Qi, J., Dong, H., Cui, B., Zhang, Q., Wu, Y., An, J., Ni, N., Liu, C., Han, Y., Zhang, S., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Deng, J. ORCID: https://orcid.org/0000-0002-4489-7556, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514 and Du, J. ORCID: https://orcid.org/0000-0002-2990-3575
Oncogene 43
(18): 1328-1340.
2 May 2024
Cancer evolution: a multifaceted affair.
Ciriello, G. ORCID: https://orcid.org/0000-0003-2021-8683, Magnani, L. ORCID: https://orcid.org/0000-0002-7534-0785, Aitken, S.J. ORCID: https://orcid.org/0000-0002-1897-4140, Akkari, L. ORCID: https://orcid.org/0000-0001-5479-641X, Behjati, S. ORCID: https://orcid.org/0000-0002-6600-7665, Hanahan, D. ORCID: https://orcid.org/0000-0002-0883-5251, Landau, D.A. ORCID: https://orcid.org/0000-0003-2346-9541, Lopez-Bigas, N. ORCID: https://orcid.org/0000-0003-4925-8988, Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X, Marine, J.C. ORCID: https://orcid.org/0000-0003-2433-9837, Martin-Villalba, A. ORCID: https://orcid.org/0000-0002-9405-8910, Natoli, G. ORCID: https://orcid.org/0000-0003-0711-2411, Obenauf, A.C. ORCID: https://orcid.org/0000-0002-9556-5914, Oricchio, E. ORCID: https://orcid.org/0000-0002-1690-0447, Scaffidi, P. ORCID: https://orcid.org/0000-0002-3642-4193, Sottoriva, A. ORCID: https://orcid.org/0000-0001-6709-9533, Swarbrick, A. ORCID: https://orcid.org/0000-0002-3051-5676, Tonon, G. ORCID: https://orcid.org/0000-0003-2973-5038, Vanharanta, S. ORCID: https://orcid.org/0000-0001-5619-7963 and Zuber, J. ORCID: https://orcid.org/0000-0001-8810-6835
Cancer Discovery 14
(1): 36–48.
1 January 2024
Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes.
Company, C. ORCID: https://orcid.org/0000-0002-7975-0642, Schmitt, M.J. ORCID: https://orcid.org/0000-0001-8296-5858, Dramaretska, Y. ORCID: https://orcid.org/0000-0002-9792-0465, Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658, Kertalli, S., Jiang, B. ORCID: https://orcid.org/0000-0002-5862-5471, Yin, J.A. ORCID: https://orcid.org/0000-0002-2134-8693, Aguzzi, A. ORCID: https://orcid.org/0000-0002-0344-6708, Barozzi, I. ORCID: https://orcid.org/0000-0003-0690-3473 and Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251
Nature Communications 15
(1): 897.
5 February 2024
Covering hierarchical dirichlet mixture models on binary data to enhance genomic stratifications in onco-hematology.
Dall'Olio, D. ORCID: https://orcid.org/0000-0003-0196-6870, Sträng, E., Turki, A.T., Tettero, J.M., Barbus, M., Schulze-Rath, R. ORCID: https://orcid.org/0000-0003-4589-7213, Elicegui, J.M., Matteuzzi, T., Merlotti, A. ORCID: https://orcid.org/0000-0002-3648-2828, Carota, L., Sala, C. ORCID: https://orcid.org/0000-0002-4889-1047, Della Porta, M.G., Giampieri, E., Hernández-Rivas, J.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Castellani, G.
PLoS Computational Biology 20
(2): e1011299.
2 February 2024
Fraternal twins at work: Structures of PLD3/4 reveal mechanism for lysosomal nucleic acid breakdown.
Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Damme, M.
Structure 32
(6): 645-647.
6 June 2024
Systematic benchmarking of single-cell ATAC-sequencing protocols.
De Rop, F.V. ORCID: https://orcid.org/0000-0001-5241-924X, Hulselmans, G., Flerin, C. ORCID: https://orcid.org/0000-0003-1883-871X, Soler-Vila, P., Rafels, A., Christiaens, V., González-Blas, C.B., Marchese, D., Caratù, G. ORCID: https://orcid.org/0000-0003-1085-8062, Poovathingal, S., Rozenblatt-Rosen, O. ORCID: https://orcid.org/0000-0001-6313-3570, Slyper, M., Luo, W. ORCID: https://orcid.org/0000-0002-7041-823X, Muus, C. ORCID: https://orcid.org/0000-0003-2779-0893, Duarte, F. ORCID: https://orcid.org/0000-0002-1261-4929, Shrestha, R., Bagdatli, S.T., Corces, M.R. ORCID: https://orcid.org/0000-0001-7465-7652, Mamanova, L., Knights, A., Meyer, K.B. ORCID: https://orcid.org/0000-0001-5906-1498, Mulqueen, R. ORCID: https://orcid.org/0000-0002-3903-7594, Taherinasab, A., Maschmeyer, P. ORCID: https://orcid.org/0000-0002-1705-5302, Pezoldt, J. ORCID: https://orcid.org/0000-0001-7143-5691, Lambert, C.L.G., Iglesias, M. ORCID: https://orcid.org/0000-0003-1757-7343, Najle, S.R. ORCID: https://orcid.org/0000-0002-0654-9147, Dossani, Z.Y. ORCID: https://orcid.org/0000-0001-9264-6340, Martelotto, L.G., Burkett, Z. ORCID: https://orcid.org/0000-0002-5153-485X, Lebofsky, R. ORCID: https://orcid.org/0000-0002-3728-6415, Martin-Subero, J.I. ORCID: https://orcid.org/0000-0001-8809-5195, Pillai, S., Sebé-Pedrós, A. ORCID: https://orcid.org/0000-0002-9896-9746, Deplancke, B. ORCID: https://orcid.org/0000-0001-9935-843X, Teichmann, S.A. ORCID: https://orcid.org/0000-0002-6294-6366, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Braun, T.P., Adey, A.C. ORCID: https://orcid.org/0000-0001-7648-8717, Greenleaf, W.J. ORCID: https://orcid.org/0000-0003-1409-3095, Buenrostro, J.D. ORCID: https://orcid.org/0000-0001-9958-3987, Regev, A. ORCID: https://orcid.org/0000-0003-3293-3158, Aerts, S. ORCID: https://orcid.org/0000-0002-8006-0315 and Heyn, H. ORCID: https://orcid.org/0000-0002-3276-1889
Nature Biotechnology 42
(6): 916-926.
June 2024
Third-generation anti-CD19 CAR T cells for relapsed/refractory chronic lymphocytic leukemia: a phase 1/2 study.
Derigs, P. ORCID: https://orcid.org/0000-0002-4670-8851, Schubert, M.L., Dreger, P. ORCID: https://orcid.org/0000-0002-7429-8570, Schmitt, A., Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Röthemeier, C., Neuber, B., Hückelhoven-Krauss, A., Brüggemann, M. ORCID: https://orcid.org/0000-0001-5514-5010, Bernhard, H., Kobbe, G., Lindemann, A., Rummel, M., Michels, B., Korell, F., Ho, A.D., Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232 and Schmitt, M. ORCID: https://orcid.org/0000-0002-1579-1509
Leukemia 38
(11): 2419-2428.
November 2024
RIF1 acts as a gatekeeper of B cell identity during late differentiation.
Di Virgilio, Michela ORCID: https://orcid.org/0000-0001-5189-0793
[Dataset]
8 February 2024
Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly.
Dick, A. ORCID: https://orcid.org/0000-0003-0580-1897, Mikirtumov, V. ORCID: https://orcid.org/0009-0004-6849-4825, Fuchs, J., Krupp, F. ORCID: https://orcid.org/0000-0002-0402-8647, Olal, D., Bendl, E., Sprink, T. ORCID: https://orcid.org/0000-0002-0760-6828, Diebolder, C. ORCID: https://orcid.org/0000-0001-7694-7362, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274, Kochs, G., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Structure 32
(8): 1068-1078.
8 August 2024
Literature review: potential non-thermal molecular effects of external radiofrequency electromagnetic fields on cancer.
Dieper, A., Scheidegger, S., Füchslin, R.M., Veltsista, P.D., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X, Weyland, M., Gerster, D., Beck, M., Bengtsson, O., Zips, D. and Ghadjar, P. ORCID: https://orcid.org/0000-0002-2747-165X
International Journal of Hyperthermia 41
(1): 2379992.
17 July 2024
Comparison of R-CHOP-14 and R-mini-CHOP in older adults with diffuse large B-cell lymphoma - a retrospective multicenter cohort study.
Dilbaz, Z.G., Denker, S., Ankermann, C., Bittenbring, J.T., Kaddu-Mulindwa, D., Kunte, A.S., Hünecke, S., Poeschel, V., Stilgenbauer, S., Thurner, L., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Bewarder, M. and Christofyllakis, K. ORCID: https://orcid.org/0000-0002-0308-388X
European Journal of Haematology 113
(5): 675-684.
November 2024
Orientation regulation of class-switch recombination in human B cells.
Du, L. ORCID: https://orcid.org/0000-0002-8448-2187, Oksenych, V., Wan, H., Ye, X., Dong, J., Ye, A.Y., Abolhassani, H. ORCID: https://orcid.org/0000-0002-4838-0407, Vlachiotis, S., Zhang, X., de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157, Hammarström, L., van der Burg, M., Alt, F.W. and Pan-Hammarström, Q. ORCID: https://orcid.org/0000-0003-1990-8804
Journal of Immunology 213
(8): 1093-1104.
15 October 2024
Effective symptom relief through continuous integration of palliative care in advanced renal cell carcinoma patients: comprehensive measurement using the palliative care base assessment.
Dörr, A. ORCID: https://orcid.org/0009-0005-4464-307X, Vogel, I., Wittenbecher, F., Westermann, J., Thuss-Patience, P., Ahn, J. ORCID: https://orcid.org/0000-0002-5631-4143, Pelzer, U., Hardt, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Flörcken, A. ORCID: https://orcid.org/0000-0001-6462-7214
Palliative Care and Social Practice 18
: 26323524241260424.
24 June 2024
Thrombus or tumor? A case report of a rare sarcoma entity: intimal sarcoma of the pulmonary arteries.
Dörr, A., Flörcken, A, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Capper, D., Von Deimling, A., Kaul, D., Märdian, S., Starck, C., Horst, D., Dragomir, M.P., Schäfer, F.M. and Jarosch, A.
Molecular Biology Reports 51
: 568.
24 April 2024
Detection of Bombali virus in a Mops condylurus bat in Kyela, Tanzania.
Düx, A., Lwitiho, S.E., Ayouba, A. ORCID: https://orcid.org/0000-0002-5081-1632, Röthemeier, C., Merkel, K., Weiss, S. ORCID: https://orcid.org/0000-0002-4835-3695, Thaurignac, G. ORCID: https://orcid.org/0000-0002-8679-0546, Lander, A., Kouadio, L. ORCID: https://orcid.org/0000-0003-1819-3333, Nowak, K. ORCID: https://orcid.org/0000-0001-7537-5200, Corman, V. ORCID: https://orcid.org/0000-0002-3605-0136, Drosten, C., Couacy-Hymann, E., Krüger, D.H., Kurth, A. ORCID: https://orcid.org/0000-0002-9660-9878, Calvignac-Spencer, S., Peeters, M., Ntinginya, N.E., Leendertz, F.H. and Mangu, C.
Viruses 16
(8): 1227.
August 2024
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation.
Eitler, J. ORCID: https://orcid.org/0000-0002-3175-2438, Rackwitz, W., Wotschel, N., Gudipati, V., Murali Shankar, N., Sidorenkova, A., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Ortiz-Montero, P., Opitz, C., Künzel, S.R., Michen, S., Temme, A., Loureiro, L.R., Feldmann, A., Bachmann, M., Boissel, L., Klingemann, H., Wels, W.S. ORCID: https://orcid.org/0000-0001-9858-3643 and Tonn, T. ORCID: https://orcid.org/0000-0001-9580-2193
Journal for ImmunoTherapy of Cancer 12
(2): e008155.
27 February 2024
Targeted perturb-seq reveals EGR1 and FOS as key regulators of the transcriptional RAF-MAPK response.
El Kassem, G., Sieber, A., Klinger, B. ORCID: https://orcid.org/0000-0003-0242-1506, Uhlitz, F., Steinbrecht, D., van Bentum, M., Hillmer, J., von Schlichting, J., Schäfer, R., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447 and Boettcher, M.
bioRxiv
: 2024.01.13.575500.
15 January 2024
MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer.
Erdem, M. ORCID: https://orcid.org/0009-0009-1743-0924, Lee, K.H., Hardt, M., Regan, J.L. ORCID: https://orcid.org/0000-0001-9987-7942, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Mokrizkij, M., Regenbrecht, C. ORCID: https://orcid.org/0000-0001-9494-5977 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cancers 16
(3): 604.
31 January 2024
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19.
Essex, M. ORCID: https://orcid.org/0000-0001-8758-7497, Millet Pascual-Leone, B.L. ORCID: https://orcid.org/0000-0003-4287-282X, Löber, U. ORCID: https://orcid.org/0000-0001-7468-9531, Kuhring, M. ORCID: https://orcid.org/0000-0002-3287-0313, Zhang, B., Brüning, U. ORCID: https://orcid.org/0000-0003-0112-4032, Fritsche-Guenther, R. ORCID: https://orcid.org/0000-0002-6965-0226, Krzanowski, M. ORCID: https://orcid.org/0000-0002-5319-0982, Fiocca Vernengo, F. ORCID: https://orcid.org/0000-0003-2293-5598, Brumhard, S., Röwekamp, I. ORCID: https://orcid.org/0000-0001-8365-2546, Bielecka, A.A., Lesker, T.R., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Mantei, A. ORCID: https://orcid.org/0009-0006-3003-158X, Meisel, C., Caesar, S., Thibeault, C., Corman, V.M. ORCID: https://orcid.org/0000-0002-3605-0136, Marko, L. ORCID: https://orcid.org/0000-0003-1888-5575, Suttorp, N., Strowig, T. ORCID: https://orcid.org/0000-0003-0185-1459, Kurth, F. ORCID: https://orcid.org/0000-0002-3807-473X, Sander, L.E. ORCID: https://orcid.org/0000-0002-0476-9947, Li, Y. ORCID: https://orcid.org/0000-0003-4022-7341, Kirwan, J.A. ORCID: https://orcid.org/0000-0002-5423-1651, Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993 and Opitz, B. ORCID: https://orcid.org/0000-0003-1276-836X
NPJ Biofilms and Microbiomes 10
(1): 66.
1 August 2024
In vivo sequential mutagenesis in germinal center B cells using a dual-recombinase approach: FOXO1 re-expression upon FOXO1 knockout rescues class switch recombination.
Farré Díaz, C. ORCID: https://orcid.org/0000-0003-4306-2108, Kabrani, E. ORCID: https://orcid.org/0000-0003-0834-9912, Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Salomon, C. ORCID: https://orcid.org/0009-0000-6723-6497, Wunderlich, F.T., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
bioRxiv
: 2024.05.17.592915.
22 May 2024
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
Fasciani, I., Petragnano, F., Wang, Z. ORCID: https://orcid.org/0009-0000-0062-7119, Edwards, R., Telugu, N. ORCID: https://orcid.org/0000-0003-4509-7056, Pietrantoni, I., Zabel, U., Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Grieben, M., Terzenidou, M.E., Di Gregorio, J., Pellegrini, C., Santini, S., Taddei, A.R., Pohl, B., Aringhieri, S., Carli, M., Aloisi, G., Marampon, F., Charlesworth, E., Roman, A. ORCID: https://orcid.org/0000-0001-9440-9752, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Flati, V., Giorgi, F., Amicarelli, F., Tobin, A.B., Scarselli, M., Tokatlidis, K., Rossi, M., Lohse, M.J. ORCID: https://orcid.org/0000-0002-0599-3510, Annibale, P. ORCID: https://orcid.org/0000-0003-3208-5347 and Maggio, R. ORCID: https://orcid.org/0000-0003-4436-2356
PLoS Biology 22
(4): e3002582.
29 April 2024
Wie weiblich ist die Onkologie in Deutschland? [How feminine is oncology in Germany?].
Fehm, T., Behrens, B., Friebe, V., Krawczyk, N., Bleckmann, A., Höpken, U. ORCID: https://orcid.org/0000-0002-0776-4893, Wardelmann, E., Heinrich, K., Duda, A., Gögel, S., Wesselmann, S., Nothacker, M., Schmalfeldt, B. and Hasenburg, A.
Forum 39
: 212-216.
June 2024
IGF1R is protective in pneumococcal pneumonia.
Felten, M. ORCID: https://orcid.org/0000-0001-5808-5025, Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Letsiou, E., Arnedo, E.A., Piñeiro-Hermida, S., López, I.P., Dietert, K., Firsching, T., Gruber, A.D., Fatykhova, D., Hocke, A., Lingscheid, T., Lienau, J., Rohde, G., Pichel, J.G. and Witzenrath, M.
bioRxiv
: 2024.09.11.612370.
11 September 2024
Impact of individualized treatment on recovery from fatigue and return to work in survivors of advanced stage Hodgkin Lymphoma: results from the randomized international GHSG HD18 trial.
Ferdinandus, J. ORCID: https://orcid.org/0000-0002-3481-7997, Müller, H., Damaschin, C., Jacob, A.S., Meissner, J., Krasniqi, F., Mey, U., Schöndube, D., Thiemer, J., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Zijlstra, J., Greil, R., Feuring-Buske, M., Markova, J. ORCID: https://orcid.org/0000-0001-8633-4789, Rüffer, J.U., Kobe, C., Eich, H.T., Baues, C., Fuchs, M., Borchmann, P. and Behringer, K.
Annals of Oncology 35
(3): 276-284.
March 2024
L-glyceraldehyde inhibits neuroblastoma cell growth via a
multi-modal mechanism on metabolism and Signaling.
Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Kempa, R., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Rayman, L., Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Arlt, B. ORCID: https://orcid.org/0000-0002-6665-4037, Spruessel, A., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Cancers 16
(9): 1664.
May 2024
Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease.
Friedrich, V.D., Pennitz, P., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Adler, J.M., Postmus, D., Müller, K., Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Prigann, J., Pott, F., Vladimirova, D., Hoefler, T., Goekeri, C., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Goffinet, C., Saliba, A.E., Scholz, M., Witzenrath, M., Trimpert, J., Kirsten, H. and Nouailles, G.
EBioMedicine 108
: 105312.
October 2024
Iterative Bleaching Extends Multiplexity (IBEX) Knowledge-Base.
Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534
[Dataset]
29 July 2024
Follow-up of the GHSG HD16 trial of PET-guided treatment in early-stage favorable Hodgkin lymphoma.
Fuchs, M., Jacob, A.S., Kaul, H., Kobe, C. ORCID: https://orcid.org/0000-0002-2909-0826, Kuhnert, G., Pabst, T. ORCID: https://orcid.org/0000-0002-6055-5257, Greil, R., Bröckelmann, P.J. ORCID: https://orcid.org/0000-0001-9662-9900, Topp, M.S., Just, M., Hertenstein, B., Soekler, M., Vogelhuber, M., Zijlstra, J.M., Keller, U.B. ORCID: https://orcid.org/0000-0002-8485-1958, Krause, S.W. ORCID: https://orcid.org/0000-0002-5259-4651, Dührsen, U., Meissner, J. ORCID: https://orcid.org/0000-0003-1908-2096, Viardot, A., Eich, H.T., Baues, C., Diehl, V., Rosenwald, A., Buehnen, I., von Tresckow, B. ORCID: https://orcid.org/0000-0003-1410-4487, Dietlein, M., Borchmann, P., Engert, A. and Eichenauer, D.A. ORCID: https://orcid.org/0000-0002-1927-3514
Leukemia 38
(1): 160-167.
January 2024
Cell states in cancer: drivers, passengers, and trailers.
Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251, Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658 and Marine, J.C. ORCID: https://orcid.org/0000-0003-2433-9837
Cancer Discovery 14
(4): 610-614.
4 April 2024
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions.
Garvanska, D.H., Alvarado, R.E. ORCID: https://orcid.org/0000-0002-1450-4854, Mundt, F.O., Lindqvist, R., Duel, J.K., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Nilsson, E. ORCID: https://orcid.org/0000-0001-8123-3292, Lokugamage, K., Johnson, B.A., Plante, J.A., Morris, D.R., Vu, M.N., Estes, L.K., McLeland, A.M., Walker, J., Crocquet-Valdes, P.A. ORCID: https://orcid.org/0000-0002-2079-0076, Mendez, B.L. ORCID: https://orcid.org/0000-0001-8541-4904, Plante, K.S., Walker, D.H., Weisser, M.B., Överby, A.K. ORCID: https://orcid.org/0000-0001-6553-0940, Mann, M., Menachery, V.D. and Nilsson, J. ORCID: https://orcid.org/0000-0003-4100-1125
EMBO Reports 25
(2): 902-926.
13 February 2024
BTK inhibition limits microglia‑perpetuated CNS inflammation and promotes myelin repair.
Geladaris, A., Torke, S. ORCID: https://orcid.org/0000-0002-1029-3623, Saberi, D., Alankus, Y.B., Streit, F., Zechel, S., Stadelmann-Nessler, C., Fischer, A., Boschert, U., Häusler, D. and Weber, M.S. ORCID: https://orcid.org/0000-0001-8409-0389
Acta Neuropathologica 147
(1): 75.
24 April 2024
Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex.
Giehler, F., Ostertag, M.S., Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Weidl, D., Sterz, K.R. ORCID: https://orcid.org/0000-0002-7225-0485, Kutz, H., Moosmann, A., Feller, S.M., Geerlof, A., Biesinger, B., Popowicz, G.M., Kirchmair, J. ORCID: https://orcid.org/0000-0003-2667-5877 and Kieser, A. ORCID: https://orcid.org/0000-0003-0783-1950
Nature Communications 15
(1): 414.
10 January 2024
5' scRNAseq data of control and n-irAEs patients pre or post ICI treatment.
Giguelay, Ambre M. ORCID: https://orcid.org/0000-0003-0417-1109
[Dataset]
2024
(Submitted)
TCR-seq data of control and n-irAEs patients pre or post ICI treatment.
Giguelay, Ambre M. ORCID: https://orcid.org/0000-0003-0417-1109
[Dataset]
2024
(Submitted)
Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data using Decoil.
Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Wittstruck, N. ORCID: https://orcid.org/0009-0000-4378-3226, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Krienelke-Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Hartebrodt, A., Euskirchen, P. ORCID: https://orcid.org/0000-0002-9138-805X, Koche, R.P., Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Reinert, K. and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Genome Research 34
(9): 1355-1364.
September 2024
Decoil: reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data.
Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Wittstruck, N. ORCID: https://orcid.org/0009-0000-4378-3226, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Krienelke-Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Hartebrodt, A. ORCID: https://orcid.org/0000-0002-9172-3137, Euskirchen, P. ORCID: https://orcid.org/0000-0002-9138-805X, Koche, R.P. ORCID: https://orcid.org/0000-0002-6820-5083, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Reinert, K. ORCID: https://orcid.org/0000-0003-3078-8129 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Lecture Notes in Computer Science 14758
: 406-411.
17 May 2024
CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment.
Greensmith, R. ORCID: https://orcid.org/0000-0001-8142-0127, Lape, I.T., Riella, C.V., Schubert, A.J. ORCID: https://orcid.org/0000-0002-6907-5276, Metzger, J.J. ORCID: https://orcid.org/0000-0001-6813-4425, Dighe, A.S., Tan, X., Hemmer, B., Rau, J. ORCID: https://orcid.org/0009-0002-6319-7990, Wendlinger, S. ORCID: https://orcid.org/0000-0001-6771-4794, Diederich, N. ORCID: https://orcid.org/0009-0008-3937-3812, Schütz, A. ORCID: https://orcid.org/0000-0002-0606-2574, Riella, L.V. ORCID: https://orcid.org/0000-0002-7636-3196 and Kaminski, M.M. ORCID: https://orcid.org/0000-0003-0429-7027
EMBO Molecular Medicine 16
(10): 2619-2637.
14 October 2024
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells.
Grimes, K. ORCID: https://orcid.org/0000-0002-4805-2366, Jeong, H. ORCID: https://orcid.org/0000-0002-1526-3343, Amoah, A., Xu, N., Niemann, J., Raeder, B. ORCID: https://orcid.org/0000-0002-9494-8884, Hasenfeld, P., Stober, C., Rausch, T. ORCID: https://orcid.org/0000-0001-5773-5620, Benito, E., Jann, J.C. ORCID: https://orcid.org/0000-0003-2200-0151, Nowak, D. ORCID: https://orcid.org/0000-0001-7130-7921, Emini, R., Hoenicka, M. ORCID: https://orcid.org/0000-0002-0986-6340, Liebold, A., Ho, A. ORCID: https://orcid.org/0000-0002-1656-0833, Shuai, S. ORCID: https://orcid.org/0000-0002-9527-8018, Geiger, H. ORCID: https://orcid.org/0000-0002-5794-5430, Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677 and Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794
Nature Genetics 56
(6): 1134-1146.
June 2024
Therapy-related AML: long-term outcome in a large cohort of AML-patients with intensive and non-intensive therapy.
Gross, S., Ihlow, J. ORCID: https://orcid.org/0000-0001-5484-1321, Busack, L., Adamiak, K., Schrezenmeier, J. ORCID: https://orcid.org/0000-0001-5239-4513, Jesse, J., Schwarz, M., Flörcken, A., Vuong, L.G., Rieger, K., Krönke, J. ORCID: https://orcid.org/0000-0002-4649-0506, le Coutre, P., Boldt, V., von Brünneck, A.C., Horst, D., Burmeister, T. ORCID: https://orcid.org/0000-0003-4843-2876, Blau, I.W., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Westermann, J.
Blood Cancer Journal 14
(1): 160.
16 September 2024
Placental growth factor promotes neural invasion and predicts disease prognosis in resectable pancreatic cancer.
Göhrig, A. ORCID: https://orcid.org/0009-0000-4341-3671, Hilfenhaus, G. ORCID: https://orcid.org/0000-0001-8764-077X, Rosseck, F., Welzel, M., Moser, B., Barbone, G., Kunze, C.A., Rein, J., Wilken, G., Böhmig, M., Malinka, T., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Bahra, M., Detjen, K.M. and Fischer, C. ORCID: https://orcid.org/0000-0003-3057-2432
Journal of Experimental & Clinical Cancer Research 43
(1): 153.
30 May 2024
A prospective observational study of real-world treatment and outcome in secondary CNS lymphoma.
Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Demel, U.M. ORCID: https://orcid.org/0000-0002-6480-4185, Fietz, A.K. ORCID: https://orcid.org/0000-0002-4395-4176, Lammer, F., Schroers, R. ORCID: https://orcid.org/0000-0003-2744-5491, Hofer, S. ORCID: https://orcid.org/0000-0002-0831-2098, Bairey, O., Braess, J. ORCID: https://orcid.org/0000-0001-6528-2078, Meier-Stiegen, A.S., Stuhlmann, R., Schmidt-Hieber, M., Hoffmann, J., Zinngrebe, B., Kaiser, U., Reimer, P., Möhle, R., Fix, P., Höffkes, H.G., Langenkamp, U., Büschenfelde, C.M.Z., Hopfer, O., Stoltefuß, A., La Rosée, P. ORCID: https://orcid.org/0000-0002-6758-7809, Blasberg, H., Jordan, K. ORCID: https://orcid.org/0000-0001-9379-5938, Kaun, S., Meurer, A., Unteroberdörster, M., von Brünneck, A.C. ORCID: https://orcid.org/0000-0003-4371-4292, Capper, D. ORCID: https://orcid.org/0000-0003-1945-497X, Heppner, F.L., Chapuy, B., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Schwartz, S. ORCID: https://orcid.org/0000-0001-8833-5793, Konietschke, F., Vajkoczy, P., Korfel, A. and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
European Journal of Cancer 196
: 113436.
January 2024
A diagnostic challenge of KIT p.V559D and BRAF p.G469A mutations in a paragastric mass.
Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Ihlow, J. ORCID: https://orcid.org/0000-0001-5484-1321, Kleo, K. ORCID: https://orcid.org/0000-0001-9136-6902, Klostermann, A., Schmidt, M., Chai, L., Knödler, M., Leyvraz, S. ORCID: https://orcid.org/0000-0002-5705-6799, Sigler, C., Sinn, B. ORCID: https://orcid.org/0000-0002-1257-9799, Maschmeyer, G. ORCID: https://orcid.org/0000-0003-2378-2466, Jegodka, Y., Benary, M. ORCID: https://orcid.org/0000-0002-3067-2030, Ott, C.E. ORCID: https://orcid.org/0000-0003-3627-3791, Tinhofer, I. ORCID: https://orcid.org/0000-0002-0512-549X, Schäfer, R. ORCID: https://orcid.org/0000-0001-7952-2124, Möbs, M. ORCID: https://orcid.org/0000-0002-1502-3032, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Keilholz, U. ORCID: https://orcid.org/0000-0001-6773-9406 and Rieke, D.T. ORCID: https://orcid.org/0000-0003-0027-7977
Oncologist 29
(10): 908-912.
October 2024
Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.
Halik, A., Tilgner, M., Silva, P., Estrada, N., Altwasser, R. ORCID: https://orcid.org/0009-0002-6216-6068, Jahn, E., Heuser, M., Hou, H.A., Pratcorona, M., Hills, R.K., Metzeler, K.H., Fenwarth, L., Dolnik, A., Terre, C., Kopp, K., Blau, O., Szyska, M. ORCID: https://orcid.org/0000-0002-4213-4600, Christen, F., Krönke, J., Vasseur, L., Löwenberg, B., Esteve, J., Valk, P.J.M., Duchmann, M., Chou, W.C., Linch, D.C., Döhner, H., Gale, R.E., Döhner, K., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Yoshida, K. and Damm, F.
Journal of Hematology & Oncology 17
(1): 70.
19 August 2024
p53 terminates the regenerative fetal-like state after colitis-associated injury.
Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Bayram, Ş. ORCID: https://orcid.org/0009-0009-5245-5473, Wetzel, A., Harnack, C., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Liu, L. ORCID: https://orcid.org/0000-0002-9553-5475, Beccacec, G. ORCID: https://orcid.org/0000-0002-6453-3725, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Monteiro, B.J.E. ORCID: https://orcid.org/0000-0001-9718-2776, Macino, M. ORCID: https://orcid.org/0000-0002-8730-9005, Flores, R.E. ORCID: https://orcid.org/0000-0001-6500-8407, Engelmann, C., Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Schupp, M. ORCID: https://orcid.org/0000-0003-3720-1052, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Science Advances 10
(43): eadp8783.
25 October 2024
10X single-nuclei RNA sequencing.
Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
[Dataset]
16 September 2024
Genomic and Transcriptomic sequencing of neuroblastoma cell lines.
Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X
[Dataset]
16 September 2024
Genomic and Transcriptomic sequencing of neuroblastoma patient.
Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X
[Dataset]
16 September 2024
Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study.
Hernández-Sánchez, A. ORCID: https://orcid.org/0000-0002-6601-3096, González, T., Sobas, M., Sträng, E., Castellani, G. ORCID: https://orcid.org/0000-0003-4892-925X, Abáigar, M., Valk, P.J.M. ORCID: https://orcid.org/0000-0002-8857-9461, Villaverde Ramiro, Á. ORCID: https://orcid.org/0000-0002-7337-7218, Benner, A., Metzeler, K.H. ORCID: https://orcid.org/0000-0003-3920-7490, Azibeiro, R., Tettero, J.M. ORCID: https://orcid.org/0000-0002-0811-0824, Martínez-López, J. ORCID: https://orcid.org/0000-0001-7908-0063, Pratcorona, M., Martínez Elicegui, J. ORCID: https://orcid.org/0000-0001-5294-6162, Mills, K.I. ORCID: https://orcid.org/0000-0002-6362-4481, Thiede, C. ORCID: https://orcid.org/0000-0003-1241-2048, Sanz, G. ORCID: https://orcid.org/0000-0002-2767-8191, Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862, Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Haferlach, T. ORCID: https://orcid.org/0000-0003-0196-2837, Turki, A.T. ORCID: https://orcid.org/0000-0003-1347-3360, Reinhardt, D., Schulze-Rath, R., Barbus, M., Hernández-Rivas, J.M., Huntly, B. ORCID: https://orcid.org/0000-0003-0312-161X, Ossenkoppele, G., Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536 and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Leukemia 38
(9): 1929-1937.
September 2024
Pangenome graph construction from genome alignments with Minigraph-Cactus.
Hickey, G. ORCID: https://orcid.org/0000-0002-2280-9404, Monlong, J., Ebler, J., Novak, A.M. ORCID: https://orcid.org/0000-0001-5828-047X, Eizenga, J.M., Gao, Y., Marschall, T. ORCID: https://orcid.org/0000-0002-9376-1030, Li, H. ORCID: https://orcid.org/0000-0003-4874-2874 and Paten, B. ORCID: https://orcid.org/0000-0001-8863-3539
Nature Biotechnology 42
(4): 663-673.
April 2024
Clonal dominance defines metastatic dissemination in pancreatic cancer.
Ho, I.L. ORCID: https://orcid.org/0000-0002-8914-710X, Li, C.Y. ORCID: https://orcid.org/0000-0003-1038-5218, Wang, F. ORCID: https://orcid.org/0000-0002-2752-781X, Zhao, L. ORCID: https://orcid.org/0000-0001-7010-9966, Liu, J., Yen, E.Y. ORCID: https://orcid.org/0000-0003-2918-5419, Dyke, C.A., Shah, R. ORCID: https://orcid.org/0000-0002-2382-9175, Liu, Z. ORCID: https://orcid.org/0000-0002-2074-1522, Çetin, A.O. ORCID: https://orcid.org/0000-0001-9142-253X, Chu, Y. ORCID: https://orcid.org/0000-0002-4188-782X, Citron, F. ORCID: https://orcid.org/0000-0002-5896-3008, Attanasio, S. ORCID: https://orcid.org/0000-0003-2576-0834, Corti, D. ORCID: https://orcid.org/0000-0002-9841-8143, Darbaniyan, F., Del Poggetto, E. ORCID: https://orcid.org/0000-0002-3648-4399, Loponte, S. ORCID: https://orcid.org/0000-0002-2849-5805, Liu, J., Soeung, M. ORCID: https://orcid.org/0000-0002-6902-898X, Chen, Z., Jiang, S., Jiang, H. ORCID: https://orcid.org/0000-0002-0862-8519, Inoue, A. ORCID: https://orcid.org/0000-0002-5000-9084, Gao, S. ORCID: https://orcid.org/0000-0002-4809-1699, Deem, A., Feng, N., Ying, H. ORCID: https://orcid.org/0000-0003-0616-2310, Kim, M. ORCID: https://orcid.org/0000-0002-8269-854X, Giuliani, V. ORCID: https://orcid.org/0000-0002-2439-4986, Genovese, G., Zhang, J. ORCID: https://orcid.org/0000-0001-5412-9860, Futreal, A. ORCID: https://orcid.org/0000-0001-8663-2671, Maitra, A. ORCID: https://orcid.org/0000-0001-7923-9978, Heffernan, T. ORCID: https://orcid.org/0000-0002-3166-8922, Wang, L. ORCID: https://orcid.org/0000-0001-9380-0266, Do, K.A. ORCID: https://orcid.org/0000-0001-8710-7131, Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251, Draetta, G. ORCID: https://orcid.org/0000-0001-5225-9610, Carugo, A. ORCID: https://orcid.org/0000-0001-5182-3320, Lin, R. ORCID: https://orcid.org/0000-0003-2244-131X and Viale, A. ORCID: https://orcid.org/0000-0003-4328-1044
Science Advances 10
(11): eadd9342.
15 March 2024
Coordinated inheritance of extrachromosomal DNAs in cancer cells.
Hung, K.L. ORCID: https://orcid.org/0000-0002-3662-4662, Jones, M.G., Wong, I.T.L. ORCID: https://orcid.org/0000-0002-9761-3422, Curtis, E.J., Lange, J.T., He, B.J. ORCID: https://orcid.org/0000-0001-8989-1521, Luebeck, J. ORCID: https://orcid.org/0000-0003-4391-979X, Schmargon, R. ORCID: https://orcid.org/0009-0009-3535-7185, Scanu, E., Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Yan, X. ORCID: https://orcid.org/0000-0002-4846-8812, Li, R. ORCID: https://orcid.org/0000-0002-3085-5267, Gnanasekar, A., Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Belk, J.A. ORCID: https://orcid.org/0000-0003-4724-6158, Liu, Z., Melillo, B. ORCID: https://orcid.org/0000-0002-9708-5287, Bafna, V., Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Werner, B. ORCID: https://orcid.org/0000-0002-6857-8699, Huang, W. ORCID: https://orcid.org/0000-0002-9016-2665, Cravatt, B.F. ORCID: https://orcid.org/0000-0001-5330-3492, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Mischel, P.S ORCID: https://orcid.org/0000-0002-4560-2211 and Chang, H.Y. ORCID: https://orcid.org/0000-0002-9459-4393
Nature 635
(8037): 201-209.
7 November 2024
Complete male-to-female sex reversal in XY mice lacking the miR-17~92 cluster.
Hurtado, A. ORCID: https://orcid.org/0000-0001-6267-704X, Mota-Gómez, I. ORCID: https://orcid.org/0000-0001-8308-8017, Lao, M. ORCID: https://orcid.org/0000-0001-6707-6825, Real, F.M. ORCID: https://orcid.org/0000-0003-0692-2260, Jedamzick, J., Burgos, M. ORCID: https://orcid.org/0000-0003-4446-9313, Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X, Jiménez, R. ORCID: https://orcid.org/0000-0003-4103-8219 and Barrionuevo, F.J. ORCID: https://orcid.org/0000-0003-2651-1530
Nature Communications 15
(1): 3809.
7 May 2024
Structure of tetrameric forms of the serotonin-gated 5-HT3(A) receptor ion channel.
Introini, B. ORCID: https://orcid.org/0000-0001-8727-1070, Cui, W. ORCID: https://orcid.org/0000-0001-9913-3118, Chu, X. ORCID: https://orcid.org/0000-0001-6801-3949, Zhang, Y., Alves, A.C., Eckhardt-Strelau, L., Golusik, S., Tol, M., Vogel, H. ORCID: https://orcid.org/0000-0001-9695-8894, Yuan, S. ORCID: https://orcid.org/0000-0001-9858-4742 and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
EMBO Journal
4 September 2024
In vitro functionality and endurance of GMP-compliant point-of-care BCMA.CAR-T cells at different timepoints of cryopreservation.
Jiang, G., Neuber, B., Hückelhoven-Krauss, A., Höpken, U. ORCID: https://orcid.org/0000-0002-0776-4893, Ding, Y., Sedloev, D., Wang, L., Reichman, A., Eberhardt, F., Wermke, M., Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950, Müller-Tidow, C., Schmitt, A. and Schmitt, M. ORCID: https://orcid.org/0000-0002-1579-1509
International Journal of Molecular Sciences 25
(3): 1394.
23 January 2024
Inference of differentiation trajectories by transfer learning across biological processes.
Jumde, G., Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Cell Systems 15
(1): 75-82.e5.
17 January 2024
Abklärung und OP-Indikationen bei malignen Lymphknoten des unteren GI-Traktes.
Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Merz, I.
In:
Chirurgie des unteren Gastrointestinaltrakts und Allgemeine Chirurgie.
Springer Reference Medizin
.
Springer, Berlin, Heidelberg, 177-185.
ISBN 978-3-662-63355-7
31 July 2024
The other site of rhabdomyosarcoma.
Kern, L., Henssen, A. ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, A. and Scheer, M. ORCID: https://orcid.org/0000-0002-0665-6268
Cancer Medicine 13
(20): e70348.
October 2024
Intestinal retinol saturase is implicated in the development of obesity and epithelial homeostasis upon injury.
Kiefer, M.F. ORCID: https://orcid.org/0000-0002-6344-2856, Meng, Y., Yang, N., Vahrenbrink, M., Wulff, S., Li, C., Wowro, S.J., Petricek, K.M., Sommerfeld, M., Flores, R.E., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Piepelow, K., Klaus, S., Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Guillot, A., Tacke, F., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Schupp, M.
American Journal of Physiology Endocrinology and Metabolism 327
(2): E203-E216.
August 2024
Aggressive lymphoma after CD19 CAR T-cell therapy.
Kobbe, G., Brüggemann, M., Baermann, B.N., Wiegand, L., Trautmann, H., Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Libertini, S., Menssen, H.D., Maier, H.J., Ulrich, P., Gao, J., Bruch, P.M., Liebers, N., Radujkovic, A., Seifert, M., Schniederjohann, C., Paramasivam, N., Fitzgerald, D., Seidel, M., Esposito, I., Germing, U., Cadeddu, R.P., Nachtkamp, K., Jäger, P., Ulrych, T., Fischer, J.C., Rox, J.M., Giesel, F., Koch, R., Antoch, G., Distler, J.H.W., Meuth, S.G., Jacobsen, M., Hübschmann, D., Lu, J., Iaccarino, I., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Damm, F. and Dietrich, S.
New England Journal of Medicine 391
(13): 1217-1226.
3 October 2024
Synthetic lethality by PARP inhibitors: new mechanism uncovered based on unresolved transcription-replication conflicts.
Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
Signal Transduction and Targeted Therapy 9
(1): 179.
29 July 2024
Interpreting deep neural networks for the prediction of translation rates.
Korbel, F. ORCID: https://orcid.org/0009-0008-0080-0514, Eroshok, E. and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
BMC Genomics 25
(1): 1061.
9 November 2024
Unlocking the secrets of structural variants in a healthy tissue.
Korbel, J.O. and Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677
Nature Genetics 56
(6): 1047-1048.
June 2024
Frequent, high density expression of surface CD38 as a potential therapeutic target in adult T-lineage acute lymphoblastic leukemia.
Koslowski, S., Glauben, R., Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Burmeister, T., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Brüggemann, M., Gökbuget, N. and Schwartz, S.
Haematologica 109
(2): 661-665.
February 2024
Molecular architecture of synaptic vesicles.
Kravčenko, U. ORCID: https://orcid.org/0009-0004-7176-8444, Ruwolt, M., Kroll, J. ORCID: https://orcid.org/0000-0003-4243-4088, Yushkevich, A. ORCID: https://orcid.org/0000-0002-8729-9281, Zenkner, M., Ruta, J. ORCID: https://orcid.org/0009-0007-0524-6885, Lotfy, R., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Rosenmund, C. ORCID: https://orcid.org/0000-0002-3905-2444, Liu, F. and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
Proceedings of the National Academy of Sciences of the United States of America 121
(49): e2407375121.
3 December 2024
A high proportion of germline variants in pediatric chronic myeloid leukemia.
Krumbholz, M., Dolnik, A., Sträng, E., Ghete, T., Skambraks, S., Hutter, S., Simonis, A., Stegelmann, F., Suttorp, M., Horn, A.H.C., Sticht, H., Haferlach, T., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Metzler, M.
Molecular Cancer 23
(1): 206.
26 September 2024
In vitro testing of drug response in primary multiple myeloma cells using a microwell-based technology.
Krüger, J., Blau, I.W., Blau, O., Bettelli, A., Rocchi, L., Bocchi, M., Krönke, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Nogai, A.
Leukemia Research 147
: 107599.
December 2024
The big chill: growth of in situ structural biology with cryo-electron tomography.
Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
QRB Discovery 5
: e10.
13 December 2024
Delphi hackathon – a new approach to develop Core Outcome Sets for blood cancers.
Lang, K.M. ORCID: https://orcid.org/0000-0001-8855-884X, de Waal, E., Bereczky, T., Dawoud, D., Geissler, J., Bolanos, N., Sanz, G., Guillevic, Y., Rivas, J.M.H., van den Berg, L., Barbus, M., Schulze-Rath, R. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Research Square
: rs-3961968/v1.
30 April 2024
Mapping lineage-traced cells across time points with moslin.
Lange, M., Piran, Z., Klein, M., Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Klein, D., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290, Theis, F.J. and Nitzan, M. ORCID: https://orcid.org/0000-0003-0074-9196
Genome Biology 25
(1): 277.
21 October 2024
Artifacts in single-cell mitochondrial DNA mutation analyses misinform phylogenetic inference.
Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Chapman, M.S. ORCID: https://orcid.org/0000-0002-5320-8193, Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Nawy, T. ORCID: https://orcid.org/0000-0003-3720-3699, Pe’er, D. ORCID: https://orcid.org/0000-0002-9259-8817 and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
bioRxiv
: 2024.07.28.605517v2.
5 October 2024
Diversification of antibodies: from V(D)J recombination to somatic exon shuffling.
Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195 and de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157
Annual Review of Cell and Developmental Biology 40
(1): 265-281.
October 2024
Soluble ACE2 correlates with severe COVID-19 and can impair antibody responses.
Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195, Ratswohl, C. ORCID: https://orcid.org/0000-0001-5413-0730, Garg, A., Schips, M., Vazquez Garcia, C. ORCID: https://orcid.org/0000-0003-4583-7616, Spatt, L., Thibeault, C., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Weiner, J. ORCID: https://orcid.org/0000-0003-1438-7819, Moreno Velásquez, I. ORCID: https://orcid.org/0000-0001-6058-8983, Gerhard, C. ORCID: https://orcid.org/0000-0001-6956-7249, Stubbemann, P., Hanitsch, L.G., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Witzenrath, M., Sander, L.E., Kurth, F., Meyer-Hermann, M. and de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157
iScience 27
(3): 109330.
15 March 2024
Additional file 2 of Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles.
Legler, Franziska, Rust, Rebekka, Hentschel, Andreas, Baum, Oliver, Wyler, Emanuel ORCID: https://orcid.org/0000-0002-9884-1806, Aschman, Tom, Preusse, Corinna, Meyer-Arndt, Lil ORCID: https://orcid.org/0000-0002-7909-020X, Büttnerova, Ivana, Förster, Alexandra, Cengiz, Derya, Teixeira Alves, Luiz Gustavo ORCID: https://orcid.org/0000-0002-5822-4168, Schneider, Julia, Kedor, Claudia, Bellmann-Strobl, Judith ORCID: https://orcid.org/0000-0003-2615-1643, Sanchin, Aminaa, Goebel, Hans-Hilmar, Landthaler, Markus ORCID: https://orcid.org/0000-0002-1075-8734, Corman, Victor, Roos, Andreas, Heppner, Frank L., Radbruch, Helena ORCID: https://orcid.org/0000-0001-6941-3397, Paul, Friedemann ORCID: https://orcid.org/0000-0002-6378-0070, Scheibenbogen, Carmen, Dengler, Nora F. and Stenzel, Werner
[Dataset]
14 August 2024
Spatial single cell profiling using imaging mass cytometry: inflammatory versus penetrating Crohn's disease.
Lehmann, M. ORCID: https://orcid.org/0000-0002-3786-7375, Weixler, B., Elezkurtaj, S., Loddenkemper, C., Kühl, A.A. and Siegmund, B. ORCID: https://orcid.org/0000-0002-0055-958X
Journal of Crohn's & Colitis 18
(8): 1305-1318.
August 2024
Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype.
Leppä, A.M. ORCID: https://orcid.org/0000-0003-0849-1759, Grimes, K. ORCID: https://orcid.org/0000-0002-4805-2366, Jeong, H. ORCID: https://orcid.org/0000-0002-1526-3343, Huang, F.Y. ORCID: https://orcid.org/0000-0002-2163-9300, Andrades, A., Waclawiczek, A., Boch, T., Jauch, A., Renders, S., Stelmach, P. ORCID: https://orcid.org/0009-0000-5270-4761, Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Karpova, D., Sohn, M., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Hasenfeld, P., Benito Garagorri, E., Thiel, V., Dolnik, A. ORCID: https://orcid.org/0000-0003-4166-2900, Rodriguez-Martin, B., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mrózek, K. ORCID: https://orcid.org/0000-0002-1408-5063, Eisfeld, A.K. ORCID: https://orcid.org/0000-0001-6442-1419, Krämer, A., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794 and Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466
Nature Genetics 56
(12): 2790-2803.
December 2024
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism.
Levy, T., Voeltzke, K., Hruby, L., Alasad, K. ORCID: https://orcid.org/0000-0002-9876-0141, Bas, Z., Snaebjörnsson, M. ORCID: https://orcid.org/0009-0008-4457-5726, Marciano, R., Scharov, K., Planque, M., Vriens, K., Christen, S., Funk, C.M. ORCID: https://orcid.org/0000-0002-0837-3237, Hassiepen, C., Kahler, A. ORCID: https://orcid.org/0000-0001-8841-0490, Heider, B., Picard, D. ORCID: https://orcid.org/0000-0003-3375-6202, Lim, J.K.M. ORCID: https://orcid.org/0000-0002-1798-8954, Stefanski, A., Bendrin, K., Vargas-Toscano, A. ORCID: https://orcid.org/0000-0002-0070-8143, Kahlert, U.D. ORCID: https://orcid.org/0000-0002-6021-1841, Stühler, K., Remke, M. ORCID: https://orcid.org/0000-0002-9404-9993, Elkabets, M., Grünewald, T.G.P. ORCID: https://orcid.org/0000-0003-0920-7377, Reichert, A.S. ORCID: https://orcid.org/0000-0001-9340-3113, Fendt, S.M. ORCID: https://orcid.org/0000-0001-6018-9296, Schulze, A. ORCID: https://orcid.org/0000-0002-8199-6422, Reifenberger, G., Rotblat, B. ORCID: https://orcid.org/0000-0003-2985-7115 and Leprivier, G. ORCID: https://orcid.org/0000-0002-2299-8989
Nature Communications 15
(1): 4083.
14 May 2024
Microscopy image reconstruction with physics-informed denoising diffusion probabilistic model.
Li, R. ORCID: https://orcid.org/0000-0002-3085-5267, Della Maggiora, G., Andriasyan, V., Petkidis, A., Yushkevich, A. ORCID: https://orcid.org/0000-0002-8729-9281, Deshpande, N., Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Yakimovich, A. ORCID: https://orcid.org/0000-0003-2458-4904
Communications Engineering 3
(1): 186.
29 December 2024
Solving the inverse problem of microscopy deconvolution with a residual Beylkin-Coifman-Rokhlin neural network.
Li, R. ORCID: https://orcid.org/0000-0002-3085-5267, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Yakimovich, A.
Lecture Notes in Computer Science 15133
: 378-395.
1 November 2024
Correlated widefield-confocal microscopy dataset.
Li, Rui ORCID: https://orcid.org/0000-0002-3085-5267, Della Maggiora Valdes, Gabriel Eugenio ORCID: https://orcid.org/0000-0002-6320-5105, Andriasyan, Vardan ORCID: https://orcid.org/0000-0002-9619-6655, Petkidis, Anthony ORCID: https://orcid.org/0000-0002-4135-9576, Yushkevich, Artsemi ORCID: https://orcid.org/0000-0002-8729-9281, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Yakimovich, Artur ORCID: https://orcid.org/0000-0003-2458-4904
[Dataset]
12 January 2024
Data from: Denoising, deblurring, and optical deconvolution for cryo-ET and light microscopy with a physics-informed deep neural network DeBCR.
Li, Rui ORCID: https://orcid.org/0000-0002-3085-5267, Yushkevich, Artsemi ORCID: https://orcid.org/0000-0002-8729-9281, Chu, Xiaofeng ORCID: https://orcid.org/0000-0001-6801-3949, Kudryashev, Mikhail ORCID: https://orcid.org/0000-0003-3550-6274 and Yakimovich, Arturo ORCID: https://orcid.org/0000-0003-2458-4904
[Dataset]
4 July 2024
Expansion and precise CRISPR-Cas9 gene repair of autologous T memory stem cells from patients with T cell immunodeficiencies.
Li, X. ORCID: https://orcid.org/0000-0002-1173-1066, Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Bio-protocol 14
(20): e5085.
20 October 2024
Precise CRISPR-Cas9 gene repair in autologous memory T cells to treat familial hemophagocytic lymphohistiocytosis.
Li, X. ORCID: https://orcid.org/0000-0002-1173-1066, Wirtz, T. ORCID: https://orcid.org/0009-0005-5677-9804, Weber, T. ORCID: https://orcid.org/0000-0003-2079-842X, Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195, Lowenstein, E.D. ORCID: https://orcid.org/0000-0003-3755-0818, Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Zach, A., Yasuda, T. ORCID: https://orcid.org/0000-0001-9997-6852, de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157, Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Müller, I. ORCID: https://orcid.org/0000-0002-7477-6632, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Science Immunology 9
(92): eadi0042.
2 February 2024
Effective inhibitor removal from wastewater samples increases sensitivity of RT-dPCR and sequencing analyses and enhances the stability of wastewater-based surveillance.
Linzner, N., Bartel, A. ORCID: https://orcid.org/0000-0002-1280-6138, Schumacher, V., Grau, J.H. ORCID: https://orcid.org/0000-0002-5328-3652, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Preuß, H., Garske, S., Bitzegeio, J., Kirst, E.B., Liere, K. ORCID: https://orcid.org/0000-0003-1504-1449, Hoppe, S., Borodina, T.A. ORCID: https://orcid.org/0000-0002-6978-016X, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Meixner, M., Sagebiel, D. and Böckelmann, U.
Microorganisms 12
(12): 2475.
December 2024
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072, Lickfett, S. ORCID: https://orcid.org/0000-0002-3726-9551, Rybak-Wolf, A. ORCID: https://orcid.org/0000-0002-1192-5290, Menacho, C. ORCID: https://orcid.org/0000-0001-9754-6322, Le, S. ORCID: https://orcid.org/0000-0002-7500-1759, Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Notopoulou, S., Dykstra, W. ORCID: https://orcid.org/0000-0002-7663-4689, Oehler, D. ORCID: https://orcid.org/0000-0002-0435-4119, López-Calcerrada, S., Mlody, B. ORCID: https://orcid.org/0000-0001-5184-1772, Otto, M. ORCID: https://orcid.org/0009-0003-1919-5880, Wu, H., Richter, Y., Roth, P. ORCID: https://orcid.org/0009-0006-8642-2993, Anand, R. ORCID: https://orcid.org/0000-0001-7337-6007, Kulka, L.A.M. ORCID: https://orcid.org/0009-0001-3640-3886, Meierhofer, D. ORCID: https://orcid.org/0000-0002-0170-868X, Glazar, P. ORCID: https://orcid.org/0000-0003-0842-0088, Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Telugu, N.S. ORCID: https://orcid.org/0000-0003-4509-7056, Hahn, T., Neuendorf, N., Miller, D.C. ORCID: https://orcid.org/0000-0001-9852-677X, Böddrich, A. ORCID: https://orcid.org/0000-0001-9118-050X, Polzin, A., Mayatepek, E. ORCID: https://orcid.org/0000-0001-8460-3738, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Olzscha, H. ORCID: https://orcid.org/0000-0002-1929-1384, Kirstein, J. ORCID: https://orcid.org/0000-0003-4990-2497, Ugalde, C. ORCID: https://orcid.org/0000-0002-9742-1877, Petrakis, S. ORCID: https://orcid.org/0000-0001-9094-3480, Cambridge, S., Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Priller, J. ORCID: https://orcid.org/0000-0001-7596-0979, Metzger, J.J. ORCID: https://orcid.org/0000-0001-6813-4425 and Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952
Nature Communications 15
(1): 7027.
22 August 2024
Mutant Huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Lisowski, Pawel ORCID: https://orcid.org/0000-0002-3634-1072
[Dataset]
27 September 2024
CD19-targeting CAR T cells protect from ANCA-induced acute kidney injury.
Lodka, D. ORCID: https://orcid.org/0009-0009-3317-6487, Zschummel, M. ORCID: https://orcid.org/0000-0002-4778-8742, Bunse, M. ORCID: https://orcid.org/0000-0002-7554-2520, Rousselle, A. ORCID: https://orcid.org/0000-0002-0641-3143, Sonnemann, J. ORCID: https://orcid.org/0000-0002-6513-7775, Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Schreiber, A. ORCID: https://orcid.org/0000-0003-1244-6379
Annals of the Rheumatic Diseases 83
(4): 499-507.
12 March 2024
Taste mapping: navigating the spatiotemporal link between diet and colorectal cancer.
Luo, Q. ORCID: https://orcid.org/0000-0003-1275-0442, Liu, Y. ORCID: https://orcid.org/0000-0003-2151-3668, Bi, M., Kuai, X. ORCID: https://orcid.org/0000-0002-6340-7452, Tian, Q., Sun, Y. and Zhuang, S.
IEEE Access 12
: 17735 - 17747.
30 January 2024
Marsupial genomes reveal how a skin membrane for gliding evolved.
Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X
Nature 629
(8010): 43-44.
2 May 2024
Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy.
Lutz, R., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Simon, M., Awwad, M.H.S. ORCID: https://orcid.org/0000-0003-4514-7199, Bauer, M., Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Beumer, N. ORCID: https://orcid.org/0000-0001-6538-0217, Jopp-Saile, L. ORCID: https://orcid.org/0000-0002-7032-3003, Sedlmeier, A. ORCID: https://orcid.org/0009-0002-0418-2131, Solé-Boldo, L. ORCID: https://orcid.org/0000-0002-6974-9066, Avanesyan, B. ORCID: https://orcid.org/0009-0004-2547-6598, Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Stelmach, P. ORCID: https://orcid.org/0009-0000-5270-4761, Steinbuss, G., Boch, T., Steiger, S. ORCID: https://orcid.org/0000-0002-4845-5042, Baertsch, M.A., Prokoph, N., Rippe, K. ORCID: https://orcid.org/0000-0001-9951-9395, Durie, B.G.M., Wickenhauser, C., Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466, Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Hübschmann, D. ORCID: https://orcid.org/0000-0002-6041-7049, Weinhold, N. ORCID: https://orcid.org/0000-0002-5464-3234, Raab, M.S. ORCID: https://orcid.org/0000-0003-4181-6922, Brors, B. ORCID: https://orcid.org/0000-0001-5940-3101, Goldschmidt, H. ORCID: https://orcid.org/0000-0003-0961-0035, Imbusch, C.D. ORCID: https://orcid.org/0000-0003-4920-551X, Hundemer, M. ORCID: https://orcid.org/0000-0002-5596-2405 and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Nature Communications 15
(1): 10396.
29 November 2024
An automated and fast sample preparation workflow for laser microdissection guided ultrasensitive proteomics.
Makhmut, A. ORCID: https://orcid.org/0009-0009-6913-4289, Qin, D. ORCID: https://orcid.org/0000-0002-9730-4072, Hartlmayr, D., Seth, A. and Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081
Molecular & Cellular Proteomics 23
(5): 100750.
May 2024
Single-cell multi-omics analysis identifies context-specific gene regulatory gates and mechanisms.
Malekpour, S.A. ORCID: https://orcid.org/0000-0002-3525-3548, Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170 and Sadeghi, M.
Briefings in Bioinformatics 25
(3): bbae180.
May 2024
Structure-based humanization of a therapeutic antibody for multiple myeloma.
Marino, S.F. ORCID: https://orcid.org/0000-0001-5696-9679 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Journal of Molecular Medicine 102
(9): 1151-1161.
September 2024
Identifying cancer cells from calling single-nucleotide variants in scRNA-seq data.
Marot-Lassauzaie, V. ORCID: https://orcid.org/0000-0002-8362-9634, Beneyto-Calabuig, S., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Velten, L., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170
Bioinformatics 40
(9): btae512.
September 2024
Additional file 2 of JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.
Mathas, Stephan ORCID: https://orcid.org/0000-0001-9626-1413
[Dataset]
15 August 2024
Despite the odds: formation of the SARS-CoV-2 methylation complex.
Matsuda, A. ORCID: https://orcid.org/0000-0003-3264-7506, Plewka, J. ORCID: https://orcid.org/0000-0002-0307-0907, Rawski, M., Mourão, A., Zajko, W., Siebenmorgen, T., Kresik, L., Lis, K., Jones, A.N. ORCID: https://orcid.org/0000-0002-2084-3625, Pachota, M., Karim, A., Hartman, K., Nirwal, S., Sonani, R., Chykunova, Y., Minia, I. ORCID: https://orcid.org/0000-0003-1012-3373, Mak, P., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Nowotny, M. ORCID: https://orcid.org/0000-0001-8632-0977, Dubin, G., Sattler, M. ORCID: https://orcid.org/0000-0002-1594-0527, Suder, P., Popowicz, G.M., Pyrć, K. ORCID: https://orcid.org/0000-0002-3867-7688 and Czarna, A.
Nucleic Acids Research 52
(11): 6441-6458.
24 June 2024
Structure-based mapping of the histone-binding pocket of KDM4D using functionalized tetrazole and pyridine core compounds.
Małecki, P.H. ORCID: https://orcid.org/0000-0003-1499-8310, Fassauer, G.M., Rüger, N., Schulig, L., Link, A., Krylova, O., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Weiss, M.S.
European Journal of Medicinal Chemistry 276
: 116642.
5 October 2024
Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease.
Menacho, C., Okawa, S., Alvarez-Merz, I., Wittich, A., Muñoz-Oreja, M., Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072, Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Rybak-Wolf, A. ORCID: https://orcid.org/0000-0002-1192-5290, Inak, G., Zakin, S., Thevandavakkam, M., Petersilie, L., Zaliani, A., Mlody, B. ORCID: https://orcid.org/0000-0001-5184-1772, Seibt, A., Donnelly, J., Woleben, K., Fernandez-Checa, J., Herebian, D., Mayatepek, E., Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Spinazzola, A., Schuelke, M. ORCID: https://orcid.org/0000-0003-2824-3891, Perlstein, E. ORCID: https://orcid.org/0000-0002-4734-4391, Rossi, A., Distelmaier, F., Holt, I.J., Pless, O. ORCID: https://orcid.org/0000-0002-1468-316X, Rose, C., Del Sol, A. and Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952
bioRxiv
: 2024.07.08.602501.
12 July 2024
CD3 aptamers promote expansion and persistence of tumor-reactive T cells for adoptive T cell therapy in cancer.
Menon, A.P., Villanueva, H., Meraviglia-Crivelli, D., van Santen, H.M., Hellmeier, J., Zheleva, A., Nonateli, F., Peters, T., Wachsmann, T.L.A., Hernandez-Rueda, M., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Schütz, G.J., Sevcsik, E., Moreno, B. and Pastor, F.
Molecular Therapy Nucleic Acids 35
(2): 102198.
11 June 2024
A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants.
Metzdorf, K., Jacobsen, H., Kim, Y., Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Kulkarni, U., Brdovčak, M.C., Materljan, J., Eschke, K., Chaudhry, M.Z., Hoffmann, M., Bertoglio, F., Ruschig, M., Hust, M., Šustić, M., Krmpotić, A., Jonjić, S., Widera, M., Ciesek, S., Pöhlmann, S., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Čičin-Šain, L.
Frontiers in Immunology 15
: 1383086.
25 July 2024
Dissecting the spatiotemporal diversity of adult neural stem cells.
Mitic, N. ORCID: https://orcid.org/0000-0003-0141-1293, Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Schneider, J., Fresmann, N. ORCID: https://orcid.org/0000-0002-9233-5101, Novoselc, K.T., Strunk, T. ORCID: https://orcid.org/0009-0001-9420-7429, Münster, L., Olivares-Chauvet, P., Ninkovic, J. ORCID: https://orcid.org/0000-0002-4381-0041 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Molecular Systems Biology 20
(4): 321-337.
2 April 2024
Sodium as an important regulator of immunometabolism.
Miyauchi, H. ORCID: https://orcid.org/0000-0003-0961-7130, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199, Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364, Stegbauer, J. ORCID: https://orcid.org/0000-0001-8994-8102, Wiig, H. ORCID: https://orcid.org/0000-0002-7740-8210, Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Jantsch, J., Kleinewietfeld, M. ORCID: https://orcid.org/0000-0002-2832-3149, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Mueller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644
Hypertension 81
(3): 426-435.
March 2024
Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia.
Mochmann, L.H., Treue, D., Bockmayr, M., Silva, P., Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Jurmeister, P., Liebig, S. ORCID: https://orcid.org/0000-0002-5494-8476, Blau, O., Schleich, K., Splettstoesser, B., Nordmann, T.M., von der Heide, E.K., Isaakidis, K., Schulze, V., Busch, C. ORCID: https://orcid.org/0000-0001-5608-2218, Siddiq, H., Schlee, C., Hester, S., Fransecky, L., Neumann, M., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Klauschen, F. and Baldus, C.D.
Cancer Gene Therapy 31
(9): 1344-1356.
September 2024
Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model.
Mohan, A.M. ORCID: https://orcid.org/0000-0001-7420-6464, Prasad, S., Schmitz-Peiffer, F., Lange, C., Lukas, M. ORCID: https://orcid.org/0000-0002-5100-4496, Koziolek, E.J., Albrecht, J., Messroghli, D., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X, Ilmer, M. ORCID: https://orcid.org/0000-0001-9597-1368, Wang, K. ORCID: https://orcid.org/0000-0002-7795-1395, Schober, L., Reul, A., Maurer, J., Friemel, J., Weber, A., Zuellig, R.A., Hantel, C., Fritsch, R., Reincke, M., Pacak, K. ORCID: https://orcid.org/0000-0002-3541-3767, Grossman, A.B. ORCID: https://orcid.org/0000-0003-1176-6186, Auernhammer, C.J., Beuschlein, F., Brenner, W., Beindorff, N. and Nölting, S. ORCID: https://orcid.org/0000-0002-7064-590X
Endocrine-Related Cancer 31
(1): e230041.
January 2024
Identification of drug-like molecules targeting the ATPase activity of dynamin-like EHD4.
Mohd, S., Oder, A., Specker, E. ORCID: https://orcid.org/0000-0002-9471-9520, Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
PLoS ONE 19
(7): e0302704.
29 July 2024
CXCR4 has a dual role in improving the efficacy of BCMA redirected CAR-NK cells in multiple myeloma.
Moles, M.W., Erdlei, H., Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Massaro, M., Fiori, A. ORCID: https://orcid.org/0000-0003-0440-4857, Bunse, M. ORCID: https://orcid.org/0000-0002-7554-2520, Schrimpf, M., Gerlach, K., Gudipati, V., Reiser, J., Mathavan, K., Goodrich, J., Huppa, J.B., Kroenke, J., Valamehr, B., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Frontiers in Immunology 15
: 1383136.
24 June 2024
AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication.
Monjé, N., Dragomir, M.P., Sinn, B.V., Hoffmann, I., Makhmut, A. ORCID: https://orcid.org/0009-0009-6913-4289, Simon, T., Kunze, C.A., Ihlow, J., Schmitt, W.D., Pohl, J., Piwonski, I., Marchenko, S., Keunecke, C., Calina, T.G., Tiso, F., Kulbe, H., Kreuzinger, C., Cacsire Castillo-Tong, D., Sehouli, J., Braicu, E.I. ORCID: https://orcid.org/0000-0001-5357-6001, Denkert, C., Darb-Esfahani, S., Kübler, K., Capper, D. ORCID: https://orcid.org/0000-0003-1945-497X, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Horst, D. ORCID: https://orcid.org/0000-0003-4755-5743, Sers, C. and Taube, E.T. ORCID: https://orcid.org/0000-0003-3041-694X
British Journal of Cancer 13
(8): 1249-1260.
3 May 2024
Evaluation of polygenic scoring methods in five biobanks shows larger variation between biobanks than methods and finds benefits of ensemble learning.
Monti, R. ORCID: https://orcid.org/0000-0002-6354-8319, Eick, L., Hudjashov, G., Läll, K., Kanoni, S., Wolford, B.N., Wingfield, B., Pain, O., Wharrie, S., Jermy, B., McMahon, A., Hartonen, T., Heyne, H., Mars, N., Lambert, S., Hveem, K., Inouye, M., van Heel, D.A., Mägi, R., Marttinen, P., Ripatti, S., Ganna, A. and Lippert, C. ORCID: https://orcid.org/0000-0001-6363-2556
American Journal of Human Genetics 111
(7): 1431-1447.
11 July 2024
Successful generation of fully human, second generation, anti-CD19 CAR T cells for clinical use in patients with diverse autoimmune disorders.
Mougiakakos, D., Sengupta, R., Gold, R., Schroers, R., Haghikia, A., Lorente, M., Pendleton, M., Register, A., Heesen, C., Kröger, N., Schett, G., Mackensen, A., Podoll, A., Gutman, J., Furie, R., Bayer, R., Distler, J.H.W., Dietrich, S., Krönke, G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Walker, K.
Cytotherapy 27
(2): 236-246.
February 2024
Natural proteome diversity links aneuploidy tolerance to protein turnover.
Muenzner, J., Trébulle, P., Agostini, F., Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Messner, C.B., Steger, M., Kilian, C., Lau, K., Barthel, N., Lehmann, A., Textoris-Taube, K., Caudal, E., Egger, A.S., Amari, F., De Chiara, M., Demichev, V., Gossmann, T.I., Mülleder, M., Liti, G., Schacherer, J., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Berman, J. and Ralser, M.
Nature 630
(8015): 149-157.
6 June 2024
MatK impacts differential chloroplast translation by limiting spliced tRNA-K(UUU) abundance.
Muino, J.M. ORCID: https://orcid.org/0000-0002-6403-7262, Ruwe, H., Qu, Y., Maschmann, S., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Zoschke, R. ORCID: https://orcid.org/0000-0002-6898-6836, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Kaufmann, K. ORCID: https://orcid.org/0000-0001-7960-6256 and Schmitz-Linneweber, C. ORCID: https://orcid.org/0000-0002-6125-4253
Plant Journal 119
(6): 2737-2752.
September 2024
Mice with renal-specific alterations 1 of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors.
Myszczyszyn, A. ORCID: https://orcid.org/0009-0006-6152-5451, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Jung, S., Penning, L.C., Fendler, A. ORCID: https://orcid.org/0000-0002-7267-0981, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
PLoS ONE 19
(3): e0282938.
21 March 2024
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation.
Mühlgrabner, V., Peters, T., Velasco Cárdenas, R.M.H., Salzer, B., Göhring, J., Plach, A., Höhrhan, M., Perez, I.D., Goncalves, V.D.R., Farfán, J.S., Lehner, M., Stockinger, H., Schamel, W.W., Schober, K., Busch, D.H., Hudecek, M., Dushek, O., Minguet, S., Platzer, R. and Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198
Science Advances 10
(36): eadj4632.
6 September 2024
Arginine methylation of the p30 C/EBPα oncoprotein regulates progenitor proliferation and myeloid differentiation.
Nguyen, L.T. ORCID: https://orcid.org/0000-0002-3228-6520, Zimmermann, K., Kowenz-Leutz, E., Dörr, D. ORCID: https://orcid.org/0000-0001-8575-7560, Schütz, A. ORCID: https://orcid.org/0000-0002-0606-2574, Schönheit, J., Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427 and Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X
iScience 27
(11): 111199.
15 November 2024
Mitochondrial genetics through the lens of single-cell multi-omics.
Nitsch, L. ORCID: https://orcid.org/0000-0003-0775-1969, Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807 and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
Nature Genetics 56
(7): 1355-1365.
July 2024
Topological reaction coordinate captures the folding transition state ensemble in a pierced lasso protein.
Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036 and Haglund, E. ORCID: https://orcid.org/0000-0002-6629-2793
Journal of Physical Chemistry B 128
(1): 117-124.
11 January 2024
Genetic characterization of primary mediastinal B-cell lymphoma: pathogenesis and patient outcomes.
Noerenberg, D., Briest, F., Hennch, C., Yoshida, K., Hablesreiter, R., Takeuchi, Y., Ueno, H., Staiger, A.M., Ziepert, M., Asmar, F., Locher, B.N., Toth, E., Weber, T., Amini, R.M., Klapper, W., Bouzani, M., Poeschel, V., Rosenwald, A., Held, G., Campo, E., Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X, Stamatopoulos, K., Kanellis, G., Anagnostopoulos, I., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Goldschmidt, N., Zinzani, P.L., Bödör, C., Rosenquist, R., Vassilakopoulos, T.P., Ott, G., Ogawa, S. and Damm, F.
Journal of Clinical Oncology 42
(4): 452-466.
1 February 2024
Update and European consensus on a patient-centered core outcome set for multiple myeloma in clinical practice and research.
Oerlemans, S., De Rooij, B.H., Bennink, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Broijl, A., D'Agostino, M., Laane, E., Lupo-Stanghellini, M.T., Perrot, A., Wester, R., Cursaru, V., Scheurer, H., Vesseur, J., Dalal, M., Sen, R., Stamm, T., Ludwig, H. and Sonneveld, P.
Haematologica 109
(6): 1956-1959.
June 2024
Recapitulating the tumor microenvironment in a dish, one cell type at a time.
Ostendorf, B.N. ORCID: https://orcid.org/0000-0003-4492-9252
Cell Reports Methods 4
(6): 100800.
17 June 2024
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Pan, X., AbdulJabbar, K. ORCID: https://orcid.org/0000-0002-4411-4435, Coelho-Lima, J., Grapa, A.I., Zhang, H., Cheung, A.H.K. ORCID: https://orcid.org/0000-0002-3913-8117, Baena, J. ORCID: https://orcid.org/0000-0002-8027-9149, Karasaki, T. ORCID: https://orcid.org/0000-0001-6863-2360, Wilson, C.R. ORCID: https://orcid.org/0000-0002-6401-2014, Sereno, M. ORCID: https://orcid.org/0000-0003-4573-9303, Veeriah, S., Aitken, S.J. ORCID: https://orcid.org/0000-0002-1897-4140, Hackshaw, A. ORCID: https://orcid.org/0000-0002-5570-5070, Nicholson, A.G., Jamal-Hanjani, M. ORCID: https://orcid.org/0000-0003-1212-1259, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018, Yuan, Y., Le Quesne, J. ORCID: https://orcid.org/0000-0003-3552-7446 and Moore, D.A. ORCID: https://orcid.org/0000-0002-6296-1312
Nature Cancer 5
(2): 347-363.
February 2024
GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway.
Park, A.Y. ORCID: https://orcid.org/0000-0002-0130-1521, Leney-Greene, M., Lynberg, M., Gabrielski, J.Q. ORCID: https://orcid.org/0000-0002-2953-2874, Xu, X., Schwarz, B., Zheng, L., Balasubramaniyam, A. ORCID: https://orcid.org/0000-0003-4168-8617, Ham, H. ORCID: https://orcid.org/0000-0002-8669-6875, Chao, B., Zhang, Y., Matthews, H.F., Cui, J., Yao, Y., Kubo, S. ORCID: https://orcid.org/0000-0001-9693-9263, Chanchu, J.M. ORCID: https://orcid.org/0009-0009-8024-8412, Morawski, A.R. ORCID: https://orcid.org/0000-0001-5995-0527, Cook, S.A., Jiang, P., Ravell, J.C., Cheng, Y.H., George, A., Faruqi, A. ORCID: https://orcid.org/0000-0002-4421-3767, Pagalilauan, A.M., Bergerson, J.R.E., Ganesan, S., Chauvin, S.D. ORCID: https://orcid.org/0000-0003-0232-751X, Aluri, J., Edwards-Hicks, J., Bohrnsen, E., Tippett, C., Omar, H., Xu, L., Butcher, G.W., Pascall, J., Karakoc-Aydiner, E., Kiykim, A., Maecker, H. ORCID: https://orcid.org/0000-0003-0795-9946, Tezcan, İ., Esenboga, S., Heredia, R.J., Akata, D., Tekin, S. ORCID: https://orcid.org/0000-0003-2641-6293, Kara, A. ORCID: https://orcid.org/0000-0001-7244-5031, Kuloglu, Z., Unal, E., Kendirli, T., Dogu, F., Karabiber, E., Atkinson, T.P., Cochet, C., Filhol, O. ORCID: https://orcid.org/0000-0003-1964-7958, Bosio, C.M., Davis, M.M. ORCID: https://orcid.org/0000-0001-6868-657X, Lifton, R.P., Pearce, E.L. ORCID: https://orcid.org/0000-0001-5592-5439, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Aytekin, C. ORCID: https://orcid.org/0000-0002-2921-5270, Şahin, G.E., Aksu, A.Ü., Uzel, G., Koneti Rao, V. ORCID: https://orcid.org/0000-0002-7881-6902, Sari, S., Boztug, K., Cagdas, D., Haskologlu, S. ORCID: https://orcid.org/0000-0002-2668-0441, Ikinciogullari, A., Schwefel, D., Vilarinho, S., Baris, S. ORCID: https://orcid.org/0000-0002-4730-9422, Ozen, A., Su, H.C. ORCID: https://orcid.org/0000-0002-5582-9110 and Lenardo, M.J. ORCID: https://orcid.org/0000-0003-1584-468X
Nature Immunology 25
(2): 282-293.
February 2024
Increased abundance of Firmicutes and depletion of Bacteroidota predicts poor outcome in chronic lymphocytic leukemia.
Paziewska, M., Szelest, Mo., Kiełbus, M., Masternak, M., Zaleska, J., Wawrzyniak, E., Kotkowska, A., Siemieniuk-Ryś, M., Morawska, M., Kalicińska, E., Jabłonowska, P., Wróbel, T., Wolska-Washer, A., Błoński, J.Z., Robak, T., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Giannopoulos, K.
Oncology letters 28
(5): 552.
November 2024
Single-cell-resolved interspecies comparison shows a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19.
Peidli, S. ORCID: https://orcid.org/0000-0002-4257-8690, Nouailles, G., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Adler, J.M., Kunder, S., Voß, A., Kazmierski, J., Pott, F., Pennitz, P., Postmus, D., Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Goffinet, C., Gruber, A.D., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Witzenrath, M., Trimpert, J., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271
Cell Reports 43
(6): 114328.
25 June 2024
Tracking rare single donor and recipient immune and leukemia cells after allogeneic hematopoietic cell transplantation using mitochondrial DNA mutations.
Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Cieri, N., Maurer, K., Kwok, M., Lyu, H., Lu, W.S., Oliveira, G., Gohil, S.H., Leshchiner, I., Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Neuberg, D.S., Kim, H.T., Li, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Ritz, J., Getz, G., Garcia, J.S., Soiffer, R.J., Livak, K.J. and Wu, C.J.
Blood Cancer Discovery 5
(6): 442-459.
1 November 2024
Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects.
Plavskin, Y. ORCID: https://orcid.org/0000-0002-6911-3009, de Biase, M.S. ORCID: https://orcid.org/0000-0003-0383-5161, Ziv, N., Janská, L., Zhu, Y.O., Hall, D.W., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Tranchina, D. and Siegal, M.L. ORCID: https://orcid.org/0000-0001-6930-2988
PLoS Biology 22
(7): e3002698.
1 July 2024
Additional file 2 of Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.
Proft, Sebastian, Leiz, Janna ORCID: https://orcid.org/0000-0002-6531-7047, Heinemann, Udo ORCID: https://orcid.org/0000-0002-8191-3850, Seelow, Dominik ORCID: https://orcid.org/0000-0002-9746-4412, Schmidt-Ott, Kai M. ORCID: https://orcid.org/0000-0002-7700-7142 and Rutkiewicz, Maria ORCID: https://orcid.org/0000-0001-8339-3230
[Dataset]
14 August 2024
Novel ectopic expression of zona pellucida 3 glycoprotein in lung cancer promotes tumor growth.
Pulawska-Moon, K. ORCID: https://orcid.org/0000-0002-9179-0444, Ponikwicka-Tyszko, D. ORCID: https://orcid.org/0000-0003-1086-7460, Lebiedzinska, W. ORCID: https://orcid.org/0000-0002-7661-3757, Pilaszewicz-Puza, A. ORCID: https://orcid.org/0000-0002-7293-0499, Bernaczyk, P. ORCID: https://orcid.org/0000-0003-3401-6599, Koda, M. ORCID: https://orcid.org/0000-0002-1678-567X, Lupu, O. ORCID: https://orcid.org/0000-0002-1348-7159, Milewska, G. ORCID: https://orcid.org/0000-0001-9008-8285, Huang, C.C.J. ORCID: https://orcid.org/0000-0003-0376-4682, Zheng, H. ORCID: https://orcid.org/0000-0002-7957-7958, Schiele, P. ORCID: https://orcid.org/0000-0002-2342-3597, Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Frentsch, M. ORCID: https://orcid.org/0000-0003-3200-210X, Li, X. ORCID: https://orcid.org/0000-0003-2261-2393, Toppari, J. ORCID: https://orcid.org/0000-0003-2228-334X, Wolczynski, S. ORCID: https://orcid.org/0000-0002-7806-1394, Coelingh Bennink, H.J.T. ORCID: https://orcid.org/0000-0003-1550-9400, Huhtaniemi, I. ORCID: https://orcid.org/0000-0001-9092-7886 and Rahman, N.A. ORCID: https://orcid.org/0000-0001-5257-870X
International Journal of Cancer 155
(10): 1846-1857.
15 November 2024
Elimusertib has antitumor activity in preclinical patient-derived pediatric solid tumor models.
Pusch, F.F. ORCID: https://orcid.org/0000-0002-7152-080X, Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Xu, R. ORCID: https://orcid.org/0000-0002-5618-246X, Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Röefzaad, C. ORCID: https://orcid.org/0000-0003-2299-6673, von Stebut, J. ORCID: https://orcid.org/0000-0001-9811-445X, Bardinet, V. ORCID: https://orcid.org/0000-0002-9583-7043, Chamorro Gonzalez, R. ORCID: https://orcid.org/0000-0002-5653-7259, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Hundsdörfer, P. ORCID: https://orcid.org/0009-0007-1158-5170, Seifert, G. ORCID: https://orcid.org/0000-0002-7109-9277, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Schäfer, B.W. ORCID: https://orcid.org/0000-0001-5988-2915, Wachtel, M. ORCID: https://orcid.org/0000-0002-6077-3692, Kühl, A.A. ORCID: https://orcid.org/0000-0003-2293-5387, Ortiz, M.V. ORCID: https://orcid.org/0000-0001-9379-314X, Wengner, A.M. ORCID: https://orcid.org/0009-0009-5772-1945, Scheer, M. ORCID: https://orcid.org/0000-0002-0665-6268 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Molecular Cancer Therapeutics 23
(4): 507-519.
2 April 2024
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Puttick, C. ORCID: https://orcid.org/0009-0006-3022-8737, Jones, T.P. ORCID: https://orcid.org/0000-0003-2748-0780, Leung, M.M. ORCID: https://orcid.org/0000-0001-9555-1080, Galvez-Cancino, F. ORCID: https://orcid.org/0000-0001-8417-1891, Liu, J. ORCID: https://orcid.org/0000-0002-9368-4696, Varas-Godoy, M. ORCID: https://orcid.org/0000-0001-5857-4793, Rowan, A., Pich, O. ORCID: https://orcid.org/0000-0002-1956-1882, Martinez-Ruiz, C. ORCID: https://orcid.org/0000-0002-4817-0565, Bentham, R., Dijkstra, K.K., Black, J.R.M. ORCID: https://orcid.org/0000-0001-5598-7752, Rosenthal, R., Kanu, N. ORCID: https://orcid.org/0000-0001-7232-1952, Litchfield, K. ORCID: https://orcid.org/0000-0002-3725-0914, Salgado, R. ORCID: https://orcid.org/0000-0002-1110-3801, Moore, D.A. ORCID: https://orcid.org/0000-0002-6296-1312, Van Loo, P. ORCID: https://orcid.org/0000-0003-0292-1949, Jamal-Hanjani, M., Quezada, S.A. ORCID: https://orcid.org/0000-0002-9763-1700, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018 and McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045
Nature Genetics 56
(10): 2121-2131.
October 2024
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Radke, J. ORCID: https://orcid.org/0000-0001-9860-2007, Meinhardt, J. ORCID: https://orcid.org/0000-0003-0366-2416, Aschman, T. ORCID: https://orcid.org/0000-0002-2101-6146, Chua, R.L., Farztdinov, V., Lukassen, S. ORCID: https://orcid.org/0000-0001-7045-6327, Ten, F.W., Friebel, E. ORCID: https://orcid.org/0000-0003-1419-2376, Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X, Franz, J. ORCID: https://orcid.org/0000-0001-7523-6622, Huhle, V.H., Mothes, R., Peters, K., Thomas, C. ORCID: https://orcid.org/0000-0002-7386-1181, Schneeberger, S., Schumann, E., Kawelke, L., Jünger, J., Horst, V., Streit, S., von Manitius, R., Körtvélyessy, P., Vielhaber, S., Reinhold, D. ORCID: https://orcid.org/0000-0002-6441-9631, Hauser, A.E., Osterloh, A., Enghard, P., Ihlow, J., Elezkurtaj, S. ORCID: https://orcid.org/0000-0002-1699-1270, Horst, D., Kurth, F. ORCID: https://orcid.org/0000-0002-3807-473X, Müller, M.A. ORCID: https://orcid.org/0000-0003-2242-5117, Gassen, N.C. ORCID: https://orcid.org/0000-0002-4265-3398, Melchert, J. ORCID: https://orcid.org/0000-0002-0494-1022, Jechow, K., Timmermann, B., Fernandez-Zapata, C. ORCID: https://orcid.org/0000-0003-4795-6053, Böttcher, C. ORCID: https://orcid.org/0000-0002-6226-586X, Stenzel, W., Krüger, E. ORCID: https://orcid.org/0000-0002-2551-242X, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Corman, V. ORCID: https://orcid.org/0000-0002-3605-0136, Stadelmann, C. ORCID: https://orcid.org/0000-0003-1766-5458, Ralser, M. ORCID: https://orcid.org/0000-0001-9535-7413, Eils, R., Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917, Mülleder, M. ORCID: https://orcid.org/0000-0001-9792-3861, Conrad, C. ORCID: https://orcid.org/0000-0001-7036-342X and Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397
Nature Neuroscience 27
(3): 409-420.
March 2024
Metadata-guided feature disentanglement for functional genomics.
Rakowski, A. ORCID: https://orcid.org/0000-0002-8134-6729, Monti, R. ORCID: https://orcid.org/0000-0002-6354-8319, Huryn, V. ORCID: https://orcid.org/0009-0009-1691-4919, Lemanczyk, M., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Lippert, C. ORCID: https://orcid.org/0000-0001-6363-2556
Bioinformatics 40
(Suppl 2): ii4-ii10.
September 2024
TransferGWAS of T1-weighted brain MRI data from UK Biobank.
Rakowski, A. ORCID: https://orcid.org/0000-0002-8134-6729, Monti, R. ORCID: https://orcid.org/0000-0002-6354-8319 and Lippert, C. ORCID: https://orcid.org/0000-0001-6363-2556
PLoS Genetics 20
(12): e1011332.
13 December 2024
The proteogenomic landscape of multiple myeloma reveals insights into disease biology and therapeutic opportunities.
Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Sapozhnikova, V., Ng, Y.L.D., Dolnik, A., Ziehm, M. ORCID: https://orcid.org/0000-0001-7074-4054, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Sträng, E., Kull, M., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Krüger, J. ORCID: https://orcid.org/0000-0001-5789-4082, Benary, M. ORCID: https://orcid.org/0000-0002-3067-2030, Müller, S. ORCID: https://orcid.org/0009-0003-6363-5599, Gao, X., Murgai, A. ORCID: https://orcid.org/0000-0001-9767-7402, Haji, M., Schmidt, A., Lutz, R., Nogai, A., Braune, J. ORCID: https://orcid.org/0000-0003-2026-2641, Laue, D. ORCID: https://orcid.org/0000-0002-7237-9414, Langer, C., Khandanpour, C., Bassermann, F. ORCID: https://orcid.org/0000-0003-4435-2609, Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536, Engelhardt, M. ORCID: https://orcid.org/0000-0003-0405-1676, Straka, C., Hundemer, M. ORCID: https://orcid.org/0000-0002-5596-2405, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Einsele, H. ORCID: https://orcid.org/0000-0002-7680-0819, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Knop, S. ORCID: https://orcid.org/0000-0003-1276-6639, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Krönke, J.
Nature Cancer 5
(8): 1267-1284.
August 2024
Single-cell genomics-based immune and disease monitoring in blood malignancies.
Rathgeber, A.C. ORCID: https://orcid.org/0000-0003-3264-1040, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164 and Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207
Clinical Hematology International 6
(2): 62-84.
14 June 2024
Liam tackles complex multimodal single-cell data integration challenges.
Rautenstrauch, P. ORCID: https://orcid.org/0000-0002-0070-4759 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Nucleic Acids Research 52
(12): e52.
8 July 2024
JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.
Redmer, T. ORCID: https://orcid.org/0000-0002-0050-9478, Raigel, M., Sternberg, C., Ziegler, R., Probst, C., Lindner, D., Aufinger, A., Limberger, T., Trachtova, K., Kodajova, P., Högler, S., Schlederer, M., Stoiber, S., Oberhuber, M., Bolis, M., Neubauer, H.A., Miranda, S., Tomberger, M., Harbusch, N.S., Garces de Los Fayos Alonso, I., Sternberg, F., Moriggl, R., Theurillat, J.P., Tichy, B., Bystry, V., Persson, J.L., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Aberger, F., Strobl, B., Pospisilova, S., Merkel, O., Egger, G., Lagger, S. and Kenner, L.
Molecular Cancer 23
(1): 114.
29 May 2024
Cellular senescence: neither irreversible nor reversible.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Journal of Experimental Medicine 221
(4): e20232136.
1 April 2024
Abnormal biomarkers predict complex FAS or FADD defects missed by exome sequencing.
Rensing-Ehl, A. ORCID: https://orcid.org/0000-0002-7031-0018, Lorenz, M.R., Führer, M., Willenbacher, W., Willenbacher, E., Sopper, S., Abinun, M., Maccari, M.E., König, C., Haegele, P., Fuchs, S., Castro, C., Kury, P., Pelle, O., Klemann, C., Heeg, M., Thalhammer, J., Wegehaupt, O., Fischer, M., Goldacker, S., Schulte, B., Biskup, S., Chatelain, P., Schuster, V., Warnatz, K., Grimbacher, B., Meinhardt, A., Holzinger, D., Oommen, P.T., Hinze, T., Hebart, H., Seeger, K., Lehmberg, K., Leahy, T.R., Claviez, A., Vieth, S., Schilling, F.H., Fuchs, I., Groß, M., Rieux-Laucat, F., Magerus, A., Speckmann, C., Schwarz, K. and Ehl, S.
Journal of Allergy and Clinical Immunology 153
(1): 297-308.
January 2024
Renal extramedullary hematopoiesis in mast cell leukemia with bone marrow fibrosis.
Rieke, D.T. ORCID: https://orcid.org/0000-0003-0027-7977, Schmalbrock, L.K. ORCID: https://orcid.org/0000-0002-6080-6175, Ihlow, J. ORCID: https://orcid.org/0000-0001-5484-1321, Kleo, K. ORCID: https://orcid.org/0000-0001-9136-6902, von Brünneck, A.C. ORCID: https://orcid.org/0000-0003-4371-4292, Nolte, F., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Ochsenreither, S. ORCID: https://orcid.org/0000-0001-6024-4312
Case Reports in Hematology 2024
: 1-6.
3 January 2024
Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Cappel, C., Cremer, N., Hoffmann, P., Koudelka, T. ORCID: https://orcid.org/0009-0008-2895-6051, Tholey, A., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Damme, M. ORCID: https://orcid.org/0000-0002-9699-9351
Nucleic Acids Research 52
(1): 370-384.
11 January 2024
Sociality shapes mitochondrial adaptations supporting hypoxia tolerance.
Rossi, A. ORCID: https://orcid.org/0000-0002-8819-9813, Ruwolt, M. ORCID: https://orcid.org/0009-0000-7220-406X, Kakouri, P., Kosten, T., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Puchkov, D. ORCID: https://orcid.org/0000-0001-8341-4847, Reznick, J. ORCID: https://orcid.org/0000-0001-7921-5466, Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Omerbašić, D. ORCID: https://orcid.org/0000-0003-1839-4856, Méndez Aranda, D. ORCID: https://orcid.org/0000-0001-9668-941X, Carai, G., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Hart, D.W. ORCID: https://orcid.org/0000-0002-4592-558X, Carraro, M. ORCID: https://orcid.org/0000-0002-4573-9306, Tommasin, L. ORCID: https://orcid.org/0000-0002-6029-0375, Bennett, N.C. ORCID: https://orcid.org/0000-0001-9748-2947, Bégay, V. ORCID: https://orcid.org/0000-0002-9002-4211, Faelber, K., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Bernardi, P. ORCID: https://orcid.org/0000-0001-9187-3736, Park, T.J. ORCID: https://orcid.org/0000-0002-2447-2948, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Liu, F. and Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352
bioRxiv
: 2024.09.30.615914.
2 October 2024
Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T. ORCID: https://orcid.org/0000-0002-9075-103X, Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Ishihama, Y., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Nature Communications 15
(1): 3146.
11 April 2024
Measurable residual disease monitoring in AML with FLT3-ITD treated with intensive chemotherapy plus midostaurin.
Rücker, F.G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Cocciardi, S., Skambraks, S., Luck, T.J., Weber, D., Krzykalla, J., Pozek, E., Schneider, I.J., Corbacioglu, A., Gaidzik, V.I., Meid, A., Aicher, S., Stegelmann, F., Schrade, A., Theis, F., Fiedler, W., Salih, H.R., Wulf, G.G., Salwender, H.J., Schroeder, T., Götze, K.S., Kühn, M.W.M., Lübbert, M., Schlenk, R.F., Benner, A., Thol, F.R., Heuser, M., Ganser, A., Döhner, H. and Döhner, K.
Blood Advances 8
(23): 6067-6080.
10 December 2024
Refinement of the prognostic impact of somatic CEBPA bZIP domain mutations in acute myeloid leukemia: Results of the AML Study Group (AMLSG).
Rücker, F.G. ORCID: https://orcid.org/0009-0003-1941-967X, Corbacioglu, A., Krzykalla, J., Cocciardi, S., Lengerke, C., Germing, U., Wulf, G., Samra, M.A., Teichmann, L.L. ORCID: https://orcid.org/0000-0001-9489-7282, Lübbert, M., Kühn, M.W.M., Bentz, M., Westermann, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Gaidzik, V.I., Meid, A., Aicher, S., Stegelmann, F., Weber, D., Schrade, A., Thol, F., Heuser, M., Ganser, A., Benner, A., Döhner, H. and Döhner, K.
HemaSphere 8
(7): e123.
July 2024
Cell-type specific prediction of RNA stability from RNA-protein interactions.
Saran, S. ORCID: https://orcid.org/0009-0001-0561-6328, Lebedeva, S. ORCID: https://orcid.org/0000-0003-0857-8256, Hirsekorn, A. and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
bioRxiv
: 2024.11.19.624283.
19 November 2024
Basal delamination during mouse gastrulation primes pluripotent cells for differentiation.
Sato, N., Rosa, V.S., Makhlouf, A., Kretzmer, H., Sampath Kumar, A., Grosswendt, S. ORCID: https://orcid.org/0000-0001-7722-2937, Mattei, A.L., Courbot, O., Wolf, S., Boulanger, J., Langevin, F., Wiacek, M., Karpinski, D., Elosegui-Artola, A., Meissner, A., Zernicka-Goetz, M. and Shahbazi, M.N. ORCID: https://orcid.org/0000-0002-1599-5747
Developmental Cell 59
(10): 1252-1268.
20 May 2024
Review of preclinical data on hyperthermia treatment in lymphomas and its potential for clinical application.
Scharr, M.V., Damm, F., Krahl, P., Dieper, A., Veltsista, P.D., Hansch, A., Beck, M., Gerster, D., Giovannelli, A.C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Zips, D. and Ghadjar, P. ORCID: https://orcid.org/0000-0002-2747-165X
International Journal of Hyperthermia 41
(1): 2418427.
3 November 2024
A biomathematical model of SARS-CoV-2 in Syrian hamsters.
Schirm, S., Nouailles, G., Kirsten, H., Trimpert, J., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Ahnert, P., Suttorp, N., Witzenrath, M. and Scholz, M.
Scientific Reports 14
(1): 30541.
18 December 2024
High-dose chemotherapy and autologous haematopoietic stem-cell transplantation in older, fit patients with primary diffuse large B-cell CNS lymphoma (MARTA): a single-arm, phase 2 trial.
Schorb, E., Isbell, L.K., Kerkhoff, A., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Braulke, F., Egerer, G., Röth, A., Schliffke, S., Borchmann, P., Brunnberg, U., Kroschinsky, F., Möhle, R., Rank, A., Wellnitz, D., Kasenda, B., Pospiech, L., Wendler, J., Scherer, F., Deckert, M., Henkes, E., von Gottberg, P., Gmehlin, D., Backenstraß, M., Jensch, A., Burger-Martin, E., Grishina, O., Fricker, H., Malenica, N., Orbán, A., Duyster, J., Ihorst, G., Finke, J. and Illerhaus, G.
Lancet Haematology 11
(3): e196-e205.
March 2024
Measurement of forces acting on single T-cell receptors.
Schrangl, L., Göhring, J. ORCID: https://orcid.org/0000-0002-6755-5305, Kellner, F. ORCID: https://orcid.org/0000-0001-5931-3798, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089
Methods in Molecular Biology 2800
: 147-165.
7 May 2024
Advanced quantification of receptor-ligand interaction lifetimes via single-molecule FRET microscopy.
Schrangl, L. ORCID: https://orcid.org/0000-0002-0420-7872, Mühlgrabner, V. ORCID: https://orcid.org/0009-0004-3331-8741, Platzer, R. ORCID: https://orcid.org/0009-0001-3399-4721, Kellner, F. ORCID: https://orcid.org/0000-0001-5931-3798, Wieland, J., Obst, R. ORCID: https://orcid.org/0000-0002-4839-207X, Toca-Herrera, J.L. ORCID: https://orcid.org/0000-0001-8951-2616, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089 and Göhring, J. ORCID: https://orcid.org/0000-0002-6755-5305
Biomolecules 14
(8): 1001.
13 August 2024
Induction of circulating ABCB1 transcripts under platinum-based chemotherapy indicates poor prognosis and a bone micrometastatic phenotype in ovarian cancer patients.
Schwarz, F.M., Kuhlmann, J.D., Kämpfer, J., Klimova, A., Klotz, D.M., Freitag, L., Herrmann, P., Zinnow, V., Smith, J., Scheller, T., Walther, W. ORCID: https://orcid.org/0000-0003-2360-1370, Wimberger, P. and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Molecular Cancer 23
(1): 174.
23 August 2024
MACC1 revisited - an in-depth review of a master of metastasis.
Schöpe, P.C. ORCID: https://orcid.org/0000-0002-5512-8832, Torke, S. ORCID: https://orcid.org/0000-0002-1029-3623, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Kortüm, B. ORCID: https://orcid.org/0000-0003-3734-6665, Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773, Dumbani, M., Güllü, N., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Biomarker Research 12
(1): 146.
23 November 2024
Transcriptional dosage of oncogenic KRAS drives lung adenocarcinoma cell states, progression and metastasis.
Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658, Cetin, A.O. ORCID: https://orcid.org/0000-0001-9142-253X, Dramaretska, Y. ORCID: https://orcid.org/0000-0002-9792-0465, Kertalli, S., Schmitt, M.J. ORCID: https://orcid.org/0000-0001-8296-5858, Naumann, H. ORCID: https://orcid.org/0000-0003-3883-0432, Zschummel, M. ORCID: https://orcid.org/0000-0002-4778-8742, Liesse-Labat, M. ORCID: https://orcid.org/0000-0001-7082-6076, Maciel, L.F. ORCID: https://orcid.org/0000-0003-2220-7072, Declercq, J. ORCID: https://orcid.org/0000-0002-1244-7729, Marine, J.C. ORCID: https://orcid.org/0000-0003-2433-9837 and Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251
bioRxiv
: 2024.12.29.630643.
30 December 2024
A mouse model of X-linked chronic granulomatous disease for the development of CRISPR/Cas9 gene therapy.
Sevim-Wunderlich, S. ORCID: https://orcid.org/0009-0008-2771-4149, Dang, T. ORCID: https://orcid.org/0009-0001-0138-7599, Rossius, J. ORCID: https://orcid.org/0009-0000-6011-9714, Schnütgen, F. ORCID: https://orcid.org/0000-0002-2426-6685 and Kuehn, R. ORCID: https://orcid.org/0000-0003-1694-9803
Genes 15
(6): 706.
June 2024
From regulation of cell fate decisions towards patient-specific treatments, insights from mechanistic models of signalling pathways.
Simon, M. ORCID: https://orcid.org/0000-0001-7213-9499, Konrath, F. ORCID: https://orcid.org/0000-0002-6843-6252 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
Current Opinion in Systems Biology 39
: 100533.
December 2024
Architecture of the Sap S-layer of Bacillus anthracis revealed by integrative structural biology.
Sogues, A. ORCID: https://orcid.org/0000-0002-5752-6009, Leigh, K. ORCID: https://orcid.org/0000-0002-6467-3330, Halingstad, E.V., Van der Verren, S.E., Cecil, A.J., Fioravanti, A. ORCID: https://orcid.org/0000-0002-4065-0839, Pak, A.J. ORCID: https://orcid.org/0000-0003-2823-6480, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Remaut, H. ORCID: https://orcid.org/0000-0002-9775-4102
Proceedings of the National Academy of Sciences of the United States of America 121
(51): e2415351121.
17 December 2024
Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex.
Sokpor, Godwin ORCID: https://orcid.org/0000-0002-7120-0793, Ulmke, P.A. ORCID: https://orcid.org/0000-0001-6960-9859, Nguyen, H.D., Pham, L., Kakani, P., Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696, Arnold, S.J. ORCID: https://orcid.org/0000-0002-2688-9210, Brand-Saberi, B. ORCID: https://orcid.org/0000-0003-3309-9724, Nguyen, H.P. and Tuoc, T. ORCID: https://orcid.org/0000-0003-2079-7259
bioRxiv
: 2024.11.05.621758.
5 November 2024
Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q.
Sollier, E. ORCID: https://orcid.org/0000-0002-3612-8562, Riedel, A. ORCID: https://orcid.org/0000-0002-0626-3894, Toprak, U.H. ORCID: https://orcid.org/0009-0009-6923-6816, Wierzbinska, J.A., Weichenhan, D. ORCID: https://orcid.org/0000-0002-7915-412X, Schmid, J.P. ORCID: https://orcid.org/0009-0001-3869-8868, Hakobyan, M. ORCID: https://orcid.org/0000-0003-4719-5186, Touzart, A. ORCID: https://orcid.org/0000-0002-8888-2292, Jahn, E. ORCID: https://orcid.org/0009-0001-0741-1166, Vick, B. ORCID: https://orcid.org/0000-0003-1956-2778, Brown-Burke, F. ORCID: https://orcid.org/0000-0001-6692-8678, Kelly, K., Kelekci, S. ORCID: https://orcid.org/0000-0002-4896-0110, Pejkovska, A. ORCID: https://orcid.org/0000-0002-8727-544X, Goyal, A. ORCID: https://orcid.org/0000-0002-9830-3987, Baehr, M., Breuer, K. ORCID: https://orcid.org/0000-0003-3716-7739, Chen, M.J.M. ORCID: https://orcid.org/0000-0002-8721-0304, Llamazares-Prada, M. ORCID: https://orcid.org/0000-0001-6559-9374, Hartmann, M. ORCID: https://orcid.org/0000-0002-4072-4658, Schoenung, M. ORCID: https://orcid.org/0000-0002-9778-9698, Correia, N., Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466, Abdullah, Y. ORCID: https://orcid.org/0000-0002-5694-0910, Klingmueller, U. ORCID: https://orcid.org/0000-0001-9845-3099, Mughal, S.S. ORCID: https://orcid.org/0000-0003-3468-8467, Brors, B. ORCID: https://orcid.org/0000-0001-5940-3101, Westermann, F. ORCID: https://orcid.org/0000-0003-1584-3636, Schlesner, M. ORCID: https://orcid.org/0000-0002-5896-4086, Vosberg, S. ORCID: https://orcid.org/0000-0002-8464-1483, Herold, T. ORCID: https://orcid.org/0000-0002-9615-9432, Greif, P.A. ORCID: https://orcid.org/0000-0002-3744-7936, Pfeifer, D., Luebbert, M., Fischer, T., Heidel, F. ORCID: https://orcid.org/0000-0003-2438-1955, Gebhard, C. ORCID: https://orcid.org/0000-0002-5459-8381, Walter, W., Haferlach, T. ORCID: https://orcid.org/0000-0003-0196-2837, Eisfeld, A.K. ORCID: https://orcid.org/0000-0001-6442-1419, Mrozek, K., Nicolet, D. ORCID: https://orcid.org/0000-0001-7796-0251, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Smeenk, L. ORCID: https://orcid.org/0000-0001-7025-8515, Erpelinck, C. ORCID: https://orcid.org/0000-0002-3965-4488, Mulet-Lazaro, R. ORCID: https://orcid.org/0000-0003-0298-7948, Delwel, R. ORCID: https://orcid.org/0000-0001-6903-3271, Ernst, A. ORCID: https://orcid.org/0000-0002-8082-3677, Scherer, M. ORCID: https://orcid.org/0000-0001-7990-6179, Lutsik, P. ORCID: https://orcid.org/0000-0001-9383-8555, Jeremias, I. ORCID: https://orcid.org/0000-0003-1773-7677, Doehner, K. ORCID: https://orcid.org/0000-0002-2261-9862, Doehner, H. ORCID: https://orcid.org/0000-0003-2116-5536, Lipka, D.B. ORCID: https://orcid.org/0000-0001-5081-7869 and Plass, C. ORCID: https://orcid.org/0000-0003-2554-3952
bioRxiv
: 2024.09.11.611224.
13 September 2024
Targeting KDM1A in neuroblastoma with NCL-1 induces a less aggressive phenotype and suppresses angiogenesis.
Sprüssel, A., Suzuki, T. ORCID: https://orcid.org/0000-0003-2439-879X, Miyata, N., Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Thole-Kliesch, T.M. ORCID: https://orcid.org/0000-0003-2714-6221, Ballagee, A., Lodrini, M. ORCID: https://orcid.org/0000-0003-4434-529X, Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412, Truss, M., Heukamp, L.C., Mathia, S., Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Rosenberger, C., Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893 and Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201
Journal of Clinical Medicine 13
(20): 6081.
October 2024
Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting.
Steinbrecht, D. ORCID: https://orcid.org/0000-0002-0976-7801, Minia, I. ORCID: https://orcid.org/0000-0003-1012-3373, Milek, M. ORCID: https://orcid.org/0000-0002-0803-8439, Meisig, J., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
Molecular Systems Biology 20
(12): 1346-1371.
2 December 2024
Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity.
Stöber, M.C., Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Wittstruck, N. ORCID: https://orcid.org/0009-0000-4378-3226, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Eggert, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Koche, R.P., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268 and Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618
Cell Reports 43
(9): 114711.
24 September 2024
Molecular subtyping of head and neck cancer - Clinical applicability and correlations with morphological characteristics.
Stögbauer, F., Otto, R., Jöhrens, K., Tinhofer, I., Keilholz, U., Poremba, C., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Leser, U., Weichert, W., Boxberg, M. ORCID: https://orcid.org/0000-0001-5989-7922 and Klinghammer, K. ORCID: https://orcid.org/0000-0001-6425-4833
Oral Oncology 149
: 106678.
February 2024
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Sun, G. ORCID: https://orcid.org/0000-0001-7549-7304, Kropp, K.A. ORCID: https://orcid.org/0000-0001-8505-3440, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Plückebaum, N. ORCID: https://orcid.org/0000-0002-9788-7335, Selich, A., Serrero, M., Dhingra, A., Cabrera, J.R., Ritter, B., Bauerfeind, R., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Schambach, A., Sodeik, B. ORCID: https://orcid.org/0000-0003-4650-3036, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Viejo-Borbolla, A. ORCID: https://orcid.org/0000-0001-6395-4010
mBio 15
(2): e0330823.
14 February 2024
EU-LIFE charter of independent life science research institutes.
Superti-Furga, G. ORCID: https://orcid.org/0000-0002-0570-1768, Agostinho, M., Bury, J., Cook, S., Durinx, C., Ender, A., van Luenen, H., Lund, A.H., Medema, R.H., Miączyńska, M., Nickel, D., Pelicci, P.G., Puisieux, A., Ripatti, S., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785, Schubeler, D., Serrano, L., Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202, Sonne-Hansen, K., Tomančák, P., Vives, J., Vontas, J. and Bettencourt-Dias, M.
FEBS Letters 598
(7): 719-724.
April 2024
Arabidopsis uses a molecular grounding mechanism and a biophysical circuit breaker to limit floral abscission signaling.
Taylor, I.W. ORCID: https://orcid.org/0000-0002-6535-8658, Patharkar, O.R. ORCID: https://orcid.org/0000-0002-1242-6549, Mijar, M. ORCID: https://orcid.org/0000-0001-7771-3357, Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Baer, J., Niederhuth, C.E. ORCID: https://orcid.org/0000-0003-3268-9079, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Benfey, P.N. ORCID: https://orcid.org/0000-0001-5302-758X and Walker, J.C. ORCID: https://orcid.org/0000-0002-2050-1641
Proceedings of the National Academy of Sciences of the United States of America 121
(44): e2405806121.
29 October 2024
Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters.
Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Baumgardt, M., Langner, C., Fischer, M., Maria Adler, J., Bushe, J., Firsching, T.C., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Grobe, J., Hoenzke, K., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Gruber, A.D., Hocke, A.C., Trimpert, J., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
BMJ Open Respiratory Research 11
(1): e001762.
29 February 2024
Acute myeloid leukemia: does sex matter?
Tettero, J.M. ORCID: https://orcid.org/0000-0002-0811-0824, Cloos, J. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Leukemia 38
(11): 2329-2331.
November 2024
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation.
Tiniakou, I. ORCID: https://orcid.org/0000-0002-8429-7045, Hsu, P.F. ORCID: https://orcid.org/0000-0001-9749-7591, Lopez-Zepeda, L.S. ORCID: https://orcid.org/0000-0001-9764-0984, Garipler, G., Esteva, E. ORCID: https://orcid.org/0000-0002-7223-6632, Adams, N.M. ORCID: https://orcid.org/0000-0001-5751-0480, Jang, G. ORCID: https://orcid.org/0000-0002-9824-1480, Soni, C. ORCID: https://orcid.org/0000-0001-7800-2338, Lau, C.M. ORCID: https://orcid.org/0000-0001-7538-094X, Liu, F., Khodadadi-Jamayran, A. ORCID: https://orcid.org/0000-0003-2495-7504, Rodrick, T.C., Jones, D., Tsirigos, A. ORCID: https://orcid.org/0000-0002-7512-8477, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Bedford, M.T. ORCID: https://orcid.org/0000-0002-8899-1050, Nimer, S.D. ORCID: https://orcid.org/0000-0003-2439-7586, Kaartinen, V. ORCID: https://orcid.org/0000-0002-9432-510X, Mazzoni, E.O. ORCID: https://orcid.org/0000-0001-8994-681X and Reizis, B. ORCID: https://orcid.org/0000-0003-1140-7853
Science Immunology 9
(94): eadi1023.
12 April 2024
Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies.
Torke, S. ORCID: https://orcid.org/0000-0002-1029-3623, Walther, W. ORCID: https://orcid.org/0000-0003-2360-1370 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cancers 16
(7): 1330.
28 March 2024
Long-term follow-up of the prospective randomized AATT study (autologous or allogeneic transplantation in patients with peripheral T-cell lymphoma).
Tournilhac, O. ORCID: https://orcid.org/0000-0002-9438-621X, Altmann, B., Friedrichs, B. ORCID: https://orcid.org/0000-0003-0945-2428, Bouabdallah, K., Leclerc, M., Cartron, G. ORCID: https://orcid.org/0000-0003-0659-9635, Turlure, P., Reimer, P., Wagner-Drouet, E. ORCID: https://orcid.org/0000-0002-0728-2253, Sanhes, L. ORCID: https://orcid.org/0000-0003-1207-7665, Houot, R. ORCID: https://orcid.org/0000-0003-1729-8213, Roussel, M. ORCID: https://orcid.org/0000-0002-4045-9428, Kroschinsky, F. ORCID: https://orcid.org/0000-0002-4235-7580, Dreger, P. ORCID: https://orcid.org/0000-0002-7429-8570, Viardot, A. ORCID: https://orcid.org/0000-0001-9593-6327, de Leval, L. ORCID: https://orcid.org/0000-0003-3994-516X, Rosenwald, A., Gaulard, P. ORCID: https://orcid.org/0000-0002-4243-905X, Wulf, G. ORCID: https://orcid.org/0000-0002-7669-3785, Villate, A., Latiere, C., Elmaagacli, A., Glass, B., Poeschel, V., Damaj, G. ORCID: https://orcid.org/0000-0002-4689-3882, Sibon, D. ORCID: https://orcid.org/0000-0002-9205-625X, Durot, E. ORCID: https://orcid.org/0000-0003-3463-0089, Bilger, K., Banos, A., Haenel, M., Dreyling, M. ORCID: https://orcid.org/0000-0002-0358-5249, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Tiab, M., Drenou, B. ORCID: https://orcid.org/0000-0002-2175-6785, Cornillon, J., Nguyen, S., Robin, M. ORCID: https://orcid.org/0000-0003-1388-9876, Nickelsen, M., Trümper, L. ORCID: https://orcid.org/0000-0002-9798-4573, Lenz, G., Ziepert, M. and Schmitz, N. ORCID: https://orcid.org/0000-0003-4938-7528
Journal of Clinical Oncology 42
(32): 3788-3794.
10 November 2024
In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis.
Tran, N.T. ORCID: https://orcid.org/0000-0003-0896-8641, Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Acevedo-Ochoa, E. ORCID: https://orcid.org/0000-0001-6466-0073, Trombke, J. ORCID: https://orcid.org/0000-0002-8746-1795, Weber, T. ORCID: https://orcid.org/0000-0003-2079-842X, Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Salomon, C. ORCID: https://orcid.org/0009-0000-6723-6497, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696
Leukemia 38
(9): 2003-2015.
September 2024
Comparable CD8(+) T-cell responses to SARS-CoV-2 vaccination in single-cell transcriptomics of recently allogeneic transplanted patients and healthy individuals.
Tranter, E. ORCID: https://orcid.org/0000-0001-7752-4126, Frentsch, M., Hütter-Krönke, M.L. ORCID: https://orcid.org/0000-0002-4531-9889, Vuong, G.L., Busch, D., Loyal, L. ORCID: https://orcid.org/0000-0001-5738-4437, Henze, L. ORCID: https://orcid.org/0000-0002-6540-4263, Rosnev, S., Blau, I.W., Thiel, A. ORCID: https://orcid.org/0000-0002-5515-4002, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Journal of Medical Virology 96
(3): e29539.
March 2024
AI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor.
Trepte, P. ORCID: https://orcid.org/0000-0002-8141-6272, Secker, C. ORCID: https://orcid.org/0000-0002-7222-536X, Olivet, J. ORCID: https://orcid.org/0000-0003-4115-5546, Blavier, J. ORCID: https://orcid.org/0000-0002-7055-6907, Kostova, S. ORCID: https://orcid.org/0000-0002-6842-6732, Maseko, S.B. ORCID: https://orcid.org/0000-0001-7025-6106, Minia, I. ORCID: https://orcid.org/0000-0003-1012-3373, Silva Ramos, E. ORCID: https://orcid.org/0000-0002-8520-9107, Cassonnet, P., Golusik, S., Zenkner, M., Beetz, S., Liebich, M.J., Scharek, N., Schütz, A. ORCID: https://orcid.org/0000-0002-0606-2574, Sperling, M. ORCID: https://orcid.org/0009-0003-9534-3398, Lisurek, M. ORCID: https://orcid.org/0009-0004-7685-5387, Wang, Y., Spirohn, K., Hao, T., Calderwood, M.A. ORCID: https://orcid.org/0000-0001-6475-1418, Hill, D.E. ORCID: https://orcid.org/0000-0001-5192-0921, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Choi, S.G. ORCID: https://orcid.org/0000-0003-0314-3958, Twizere, J.C. ORCID: https://orcid.org/0000-0002-8683-705X, Vidal, M. ORCID: https://orcid.org/0000-0003-3391-5410 and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Molecular Systems Biology 20
(4): 428-457.
2 April 2024
Plasmapheresis effectively abrogates severe liver toxicity of pegaspargase in a patient with acute lymphoblastic leukemia.
Tölle, M. ORCID: https://orcid.org/0000-0001-9843-2132, Gökbuget, N., Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Schwartz, S. ORCID: https://orcid.org/0000-0001-8833-5793
Annals of Hematology 103
(8): 3269-3271.
August 2024
Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz.
Uehata, T., Yamada, S., Ori, D., Vandenbon, A., Giladi, A., Jelinski, A., Murakawa, Y., Watanabe, H., Takeuchi, K., Toratani, K., Mino, T., Kiryu, H., Standley, D.M., Tsujimura, T., Ikawa, T., Kondoh, G., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Kawamoto, H., Rodewald, H.R., Amit, I., Yamamoto, R., Miyazaki, M. and Takeuchi, O.
Blood 143
(3): 243-257.
18 January 2024
Poxviruses induce a nuclear environment in the cytoplasm to promote viral replication.
Veratti, P., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Read, C., Scherer, M., Tan, J., Walther, P., Wider, S., Weidl, D. and Full, F.
bioRxiv
: 2024.11.21.624458.
22 November 2024
Expression of mGluR5 in pediatric Hodgkin and Non-Hodgkin lymphoma-a comparative analysis of immunohistochemical and clinical findings regarding the association between tumor and paraneoplastic neurological disease.
Viezens, I., Knierim, E., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Hauptmann, K., Fassbender, J., Morales-Gonzalez, S. ORCID: https://orcid.org/0000-0001-7279-2092, Kaindl, A.M. ORCID: https://orcid.org/0000-0001-9454-206X, Schuelke, M. ORCID: https://orcid.org/0000-0003-2824-3891 and Nikolaus, M. ORCID: https://orcid.org/0000-0002-3678-5159
Cancers 16
(13): 2452.
4 July 2024
Breakthrough infections in SARS-CoV-2-vaccinated multiple myeloma patients improve cross-protection against omicron variants.
Wagner, A., Garner-Spitzer, E. ORCID: https://orcid.org/0000-0002-5283-0458, Auer, C., Gattinger, P. ORCID: https://orcid.org/0000-0001-6724-8543, Zwazl, I., Platzer, R., Orola-Taus, M., Pichler, P. ORCID: https://orcid.org/0000-0001-8340-0197, Amman, F., Bergthaler, A. ORCID: https://orcid.org/0000-0003-0597-1976, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Stockinger, H. ORCID: https://orcid.org/0000-0001-6404-4430, Zielinski, C.C. ORCID: https://orcid.org/0000-0002-1440-9013, Valenta, R., Kundi, M. ORCID: https://orcid.org/0000-0002-2707-3213 and Wiedermann, U. ORCID: https://orcid.org/0000-0002-1302-3223
Vaccines 12
(5): 518.
9 May 2024
Editorial: The MACC1 network in cancer.
Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Siegel, F. and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Frontiers in Oncology 13
: 1343812.
5 July 2024
TransTACs: novel heterobispecific antibodies for targeted protein degradation in cancer therapy.
Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Torke, S. ORCID: https://orcid.org/0000-0002-1029-3623 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Signal Transduction and Targeted Therapy 9
(1): 331.
26 November 2024
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.
Waltho, A. ORCID: https://orcid.org/0009-0000-0059-9357, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Lenz, C. ORCID: https://orcid.org/0009-0000-2261-2823, Pluska, L. ORCID: https://orcid.org/0000-0002-8669-6533, Lambert, M., Dötsch, V. ORCID: https://orcid.org/0000-0001-5720-212X, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202
Life Science Alliance 7
(8): e202402740.
August 2024
Anti-angiogenesis and anti-immunosuppression gene therapy through targeting COUP-TFII in an in situ glioblastoma mouse model.
Wang, F., Zhang, S., Sun, F., Chen, W., Liu, C., Dong, H., Cui, B., Li, L., Sun, C., Du, W., Liu, B., Fan, W., Deng, J., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Wang, X. and Du, J.
Cancer Gene Therapy 31
(8): 1135-1150.
August 2024
Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13).
Weichenhan, D., Riedel, A., Sollier, E., Toprak, U.H., Hey, J., Breuer, K.H., Wierzbinska, J.A., Touzart, A., Lutsik, P., Bähr, M., Östlund, A., Nilsson, T., Jacobsson, S., Waraky, A., Behrens, Y.L., Göhring, G., Schlegelberger, B., Steinek, C., Harz, H., Leonhardt, H., Dolnik, A., Reinhardt, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Palmqvist, L., Lipka, D.B. and Plass, C.
Blood Advances 8
(19): 5100-5111.
8 October 2024
Structural insights into the activation mechanism of antimicrobial GBP1.
Weismehl, M. ORCID: https://orcid.org/0000-0001-7583-9095, Chu, X. ORCID: https://orcid.org/0000-0001-6801-3949, Kutsch, M. ORCID: https://orcid.org/0000-0002-9346-2196, Lauterjung, P., Herrmann, C. ORCID: https://orcid.org/0000-0002-1824-3647, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
EMBO Journal 43
(4): 615-636.
15 February 2024
Combining Data Independent Acquisition with spike-in SILAC (DIA-SiS) improves proteome coverage and quantification.
Welter, A.S. ORCID: https://orcid.org/0009-0003-9846-3889, Gerwien, M. ORCID: https://orcid.org/0000-0002-2884-4155, Kerridge, R., Alp, K.M. ORCID: https://orcid.org/0000-0001-9919-9838, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Molecular & Cellular Proteomics 23
(10): 100839.
October 2024
HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation.
Welters, C., Welters, M.L., Stadler, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Strobel, J., Hackstein, H., Dhamodaran, A. ORCID: https://orcid.org/0000-0001-7711-9593, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
Haematologica 109
(4): 1121-1127.
April 2024
Oligonucleotide library screening for identification of virus-specific T-cell receptors.
Welters, M.L., Stadler, S., Anastasopoulou, V., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Kammertöns, T. ORCID: https://orcid.org/0000-0003-3309-5141, Welters, C. ORCID: https://orcid.org/0000-0002-3098-9003 and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
European Journal of Immunology 56
(6): e2350908.
June 2024
Tissue-specific apparent mtDNA heteroplasmy and its relationship with ageing and mtDNA gene expression.
Wengert, S., Giannoulis, X., Kreitmaier, P., Kautz, P. ORCID: https://orcid.org/0000-0002-9658-1676, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Prokisch, H. ORCID: https://orcid.org/0000-0003-2379-6286, Casale, F.P. ORCID: https://orcid.org/0000-0002-5450-1981, Heinig, M. ORCID: https://orcid.org/0000-0002-5612-1720 and Cai, N. ORCID: https://orcid.org/0000-0001-7496-2075
bioRxiv
: 2024.12.11.627989.
16 December 2024
CXCR4-gerichtete Theranostics in der Hämato-Onkologie: Möglichkeiten und Herausforderungen [CXCR4-targeted theranostics in hematooncology: opportunities and challenges].
Werner, R., Haug, A., Buske, C., Heidegger, S., Illert, A.L., Bassermann, F., Herhaus, P., Buck, A., Duell, J., Topp, M.S., Kraus, S., Einsele, H., Lapa, C., Raderer, M., Lenz, G., Habringer, S., von Tresckow, B. and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Nuklearmedizin 63
(2): 57-61.
April 2024
The cycling and aging mouse female reproductive tract at single-cell resolution.
Winkler, I., Tolkachov, A., Lammers, F., Lacour, P., Daugelaite, K., Schneider, N., Koch, M.L., Panten, J., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Poth, T., Ávila, B.M.d., Schneider, A., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Odom, D.T. and Gonçalves, Â.
Cell 187
(4): 981-998.
15 February 2024
A hypoxia-epigenetics axis drives EMT in pancreatic cancer.
Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872 and Schneider, G. ORCID: https://orcid.org/0000-0003-1840-4508
Cancer Research 84
(11): 1739-1741.
1 June 2024
Gastric stem cell biology and helicobacter pylori infection.
Wizenty, J. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Current Topics in Microbiology and Immunology 444
: 1-24.
18 January 2024
Single-cell RNA-sequencing of RVFV infection.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806
Methods in Molecular Biology 2824
: 361-372.
August 2024
Pathogen dynamics and discovery of novel viruses and enzymes by deep nucleic acid sequencing of wastewater.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Lauber, C., Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Deter, A., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Wylezich, C. ORCID: https://orcid.org/0000-0002-0436-4480, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Seitz, S., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
Environment International 190
: 108875.
August 2024
PDGFRA is a conserved HAND2 effector during early cardiac development.
Xu, Y., Gehlot, R. ORCID: https://orcid.org/0009-0008-8709-2337, Capon, S.J. ORCID: https://orcid.org/0000-0003-3949-4696, Albu, M. ORCID: https://orcid.org/0009-0004-9409-8762, Gretz, J., Bloomekatz, J. ORCID: https://orcid.org/0000-0001-5816-2756, Mattonet, K., Vucicevic, D. ORCID: https://orcid.org/0000-0002-1162-6709, Talyan, S., Kikhi, K. ORCID: https://orcid.org/0000-0001-5672-3791, Günther, S. ORCID: https://orcid.org/0000-0002-5594-4549, Looso, M. ORCID: https://orcid.org/0000-0003-1495-9530, Firulli, B.A., Sanda, M., Firulli, A.B., Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340, Yelon, D. ORCID: https://orcid.org/0000-0003-3523-4053 and Stainier, D.Y.R. ORCID: https://orcid.org/0000-0002-0382-0026
Nature Cardiovascular Research 3
(12): 1531-1548.
December 2024
Cellular atlases are unlocking the mysteries of the human body.
Yanai, I. ORCID: https://orcid.org/0000-0002-8438-2741, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Lippert, C. ORCID: https://orcid.org/0000-0001-6363-2556 and Kretzmer, H. ORCID: https://orcid.org/0000-0002-0723-4980
Nature 635
(8039): 553-555.
November 2024
Grainyhead-like 2 deficiency and kidney cyst growth in a mouse model.
Yurtdas, Z.Y. ORCID: https://orcid.org/0009-0004-9131-8723, Kilic, E., Boor, P., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Jung, K. and Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142
Journal of the American Society of Nephrology 35
(7): 838-853.
July 2024
DCGG: drug combination prediction using GNN and GAE.
Ziaee, S.S., Rahmani, H. ORCID: https://orcid.org/0000-0003-2988-6178, Tabatabaei, M., Vlot, A.H.C. ORCID: https://orcid.org/0000-0001-9538-987X and Bender, A.
Progress in Artificial Intelligence 13
: 17-30.
March 2024
Smoking-associated gene expression alterations in nasal epithelium reveal immune impairment linked to lung cancer risk.
de Biase, M.S. ORCID: https://orcid.org/0000-0003-0383-5161, Massip, F. ORCID: https://orcid.org/0000-0001-5855-0935, Wei, T.T. ORCID: https://orcid.org/0000-0001-5719-721X, Giorgi, F.M. ORCID: https://orcid.org/0000-0002-7325-9908, Stark, R., Stone, A., Gladwell, A., O'Reilly, M., Schütte, D., de Santiago, I., Meyer, K.B. ORCID: https://orcid.org/0000-0001-5906-1498, Markowetz, F., Ponder, B.A.J., Rintoul, R.C. ORCID: https://orcid.org/0000-0003-3875-3780 and Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268
Genome Medicine 16
(1): 54.
8 April 2024
New coronavirus vaccine and method for designing and obtaining a virus vaccine.
Max Delbrueck Centrum fuer Molekulare in der Helmholtz Gemeinschaft.
EP-4396198-A2.
10 July 2024
LONG-read sequencing of human immunoglobulin gene introns to define a biomarker for in vivo DNA break repair.
Max Delbrueck Centrum fuer Molekulare in der Helmholtz Gemeinschaft.
WO-2024194255-A1.
26 September 2024
Long-term impact of scheduled regular endoscopic interventions for patients with primary sclerosing cholangitis.
Özdirik, B. ORCID: https://orcid.org/0000-0002-8885-737X, Veltzke-Schlieker, W., Nicklaus, J.M., Berger, H., Schmidt, D., Leonhardt, S., Penndorf, V., Adler, A., Müller, T., Wree, A., Tacke, F. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Hepatology Communications 8
(9): e0494.
September 2024
2023
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Abbosh, C., Frankell, A.M., Harrison, T., Kisistok, J., Garnett, A., Johnson, L., Veeriah, S., Moreau, M., Chesh, A., Chaunzwa, T.L., Weiss, J., Schroeder, M.R., Ward, S., Grigoriadis, K., Shahpurwalla, A., Litchfield, K., Puttick, C., Biswas, D., Karasaki, T., Black, J.R.M., Martínez-Ruiz, C., Bakir, M.A.l., Pich, O., Watkins, T.B.K., Lim, E.L., Huebner, A., Moore, D.A., Godin-Heymann, N., L'Hernault, A., Bye, H., Odell, A., Roberts, P., Gomes, F., Patel, A.J., Manzano, E., Hiley, C.T., Carey, N., Riley, J., Cook, D.E., Hodgson, D., Stetson, D., Barrett, J.C., Kortlever, R.M., Evan, G.I., Hackshaw, A., Daber, R.D., Shaw, J.A., Aerts, H.J.W.L., Licon, A., Stahl, J., Jamal-Hanjani, M., Birkbak, N.J., McGranahan, N. and Swanton, C.
Nature 616
(7957): 553-562.
20 April 2023
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous, E.T. ORCID: https://orcid.org/0000-0001-9582-9089, Stolzenberg, S., Sticht, J. ORCID: https://orcid.org/0000-0002-4307-4726, Wieczorek, M., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Günther, M., Dähn, S., Boesen, B.B., Calvo, M.M. ORCID: https://orcid.org/0009-0008-9179-127X, Biese, C., Kuppler, F., Medina-García, Á., Álvaro-Benito, M. ORCID: https://orcid.org/0000-0002-6019-3567, Höfer, T. ORCID: https://orcid.org/0000-0003-3560-8780, Noé, F. ORCID: https://orcid.org/0000-0003-4169-9324 and Freund, C. ORCID: https://orcid.org/0000-0001-7416-8226
Nature Chemical Biology 19
(10): 1196-1204.
October 2023
Evolution of 3D chromatin organization at different scales.
Acemel, R.D. ORCID: https://orcid.org/0000-0003-4120-0140 and Lupianez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X
Current Opinion in Genetics & Development 78
: 102019.
February 2023
The evolution of non-small cell lung cancer metastases in TRACERx.
Al Bakir, M., Huebner, A., Martínez-Ruiz, C., Grigoriadis, K., Watkins, T.B.K., Pich, O., Moore, D.A., Veeriah, S., Ward, S., Laycock, J., Johnson, D., Rowan, A., Razaq, M., Akther, M., Naceur-Lombardelli, C., Prymas, P., Toncheva, A., Hessey, S., Dietzen, M., Colliver, E., Frankell, A.M., Bunkum, A., Lim, E.L., Karasaki, T., Abbosh, C., Hiley, C.T., Hill, M.S., Cook, D.E., Wilson, G.A., Salgado, R., Nye, E., Stone, R.K., Fennell, D.A., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Summers, Y., Lindsay, C.R., Blackhall, F.H., Cave, J., Blyth, K.G., Nair, A., Ahmed, A., Taylor, M.N., Procter, A.J., Falzon, M., Lawrence, D., Navani, N., Thakrar, R.M., Janes, S.M., Papadatos-Pastos, D., Forster, M.D., Lee, S.M., Ahmad, T., Quezada, S.A., Peggs, K.S., Van Loo, P., Dive, C., Hackshaw, A., Birkbak, N.J., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
(7957): 534-542.
April 2023
Body composition and lung cancer-associated cachexia in TRACERx.
Al-Sawaf, O. ORCID: https://orcid.org/0000-0001-9895-0570, Weiss, J., Skrzypski, M., Lam, J.M. ORCID: https://orcid.org/0000-0001-9523-5029, Karasaki, T. ORCID: https://orcid.org/0000-0001-6863-2360, Zambrana, F., Kidd, A.C., Frankell, A.M. ORCID: https://orcid.org/0000-0002-0341-7878, Watkins, T.B.K., Martínez-Ruiz, C. ORCID: https://orcid.org/0000-0002-4817-0565, Puttick, C., Black, J.R.M., Huebner, A. ORCID: https://orcid.org/0000-0001-8009-4999, Bakir, M.A. ORCID: https://orcid.org/0000-0002-0846-8332, Sokač, M., Collins, S., Veeriah, S., Magno, N., Naceur-Lombardelli, C., Prymas, P., Toncheva, A., Ward, S. ORCID: https://orcid.org/0000-0002-6777-5279, Jayanth, N., Salgado, R. ORCID: https://orcid.org/0000-0002-1110-3801, Bridge, C.P. ORCID: https://orcid.org/0000-0002-2242-351X, Christiani, D.C. ORCID: https://orcid.org/0000-0002-0301-0242, Mak, R.H. ORCID: https://orcid.org/0000-0002-8754-0565, Bay, C., Rosenthal, M., Sattar, N., Welsh, P. ORCID: https://orcid.org/0000-0002-7970-3643, Liu, Y. ORCID: https://orcid.org/0000-0002-6419-1980, Perrimon, N. ORCID: https://orcid.org/0000-0001-7542-472X, Popuri, K., Beg, M.F., McGranahan, N., Hackshaw, A. ORCID: https://orcid.org/0000-0002-5570-5070, Breen, D.M., O'Rahilly, S. ORCID: https://orcid.org/0000-0003-2199-4449, Birkbak, N.J. ORCID: https://orcid.org/0000-0003-1613-9587, Aerts, H.J.W.L. ORCID: https://orcid.org/0000-0002-2122-2003, Jamal-Hanjani, M. ORCID: https://orcid.org/0000-0003-1212-1259 and Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018
Nature Medicine 29
(4): 846-858.
April 2023
Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Alcaniz, J., Winkler, L. ORCID: https://orcid.org/0000-0003-3350-1189, Dahlmann, M., Becker, M., Orthmann, A., Haybaeck, J., Krassnig, S., Skofler, C., Kratzsch, T., Kuhn, S.A., Jödicke, A., Linnebacher, M., Fichtner, I., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Hoffmann, J.
Frontiers in Oncology 13
: 1129627.
11 April 2023
Patient-reported ability to walk 4 m and to wash: New clinical endpoints and predictors of survival in patients with pre-terminal cancer.
Anker, M.S. ORCID: https://orcid.org/0000-0002-4406-8555, Lena, A., Roeland, E.J., Porthun, J., Schmitz, S., Hadzibegovic, S., Sikorski, P., Wilkenshoff, U., Fröhlich, A.K., Ramer, L.V., Rose, M., Eucker, J., Rassaf, T., Totzeck, M., Lehmann, L.H., von Haehling, S., Coats, A.J.S., Friede, T. ORCID: https://orcid.org/0000-0001-5347-7441, Butler, J., Anker, S.D., Riess, H., Landmesser, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Ahn, J.
Journal of Cachexia Sarcopenia and Muscle 14
(4): 1670-1681.
August 2023
Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire.
Anker, M.S., Potthoff, S.K., Lena, A., Porthun, J., Hadzibegovic, S., Evertz, R., Denecke, C., Fröhlich, A.K., Sonntag, F., Regitz-Zagrosek, V., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Spertus, J.A., Anker, S.D., Karakas, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 25
(9): 1635-1647.
September 2023
Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M. ORCID: https://orcid.org/0000-0003-4417-4750, Liman, T.G., Strzelecka, P.M. ORCID: https://orcid.org/0000-0003-0226-6788, Kufner, A., Löwe, P. ORCID: https://orcid.org/0000-0002-6222-5323, Huo, S. ORCID: https://orcid.org/0000-0002-0119-7517, Stein, C.M. ORCID: https://orcid.org/0000-0002-9015-7671, Piper, S.K. ORCID: https://orcid.org/0000-0002-0147-8992, Tilgner, M. ORCID: https://orcid.org/0000-0003-3196-6214, Sperber, P.S. ORCID: https://orcid.org/0000-0002-9534-2374, Dimitriou, S., Heuschmann, P. ORCID: https://orcid.org/0000-0002-2681-3515, Hablesreiter, R., Harms, C. ORCID: https://orcid.org/0000-0002-2063-2860, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Weber, J.E. ORCID: https://orcid.org/0000-0002-1666-6021, Endres, M. ORCID: https://orcid.org/0000-0001-6520-3720 and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Blood 141
(7): 787-799.
16 February 2023
Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles.
Aschman, T. ORCID: https://orcid.org/0000-0002-2101-6146, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Baum, O., Hentschel, A., Rust, R., Legler, F., Preusse, C., Meyer-Arndt, L., Büttnerova, I., Förster, A., Cengiz, D., Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Schneider, J., Kedor, C., Bellmann-Strobl, J., Sanchin, A., Goebel, H.H., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Corman, V., Roos, A., Heppner, F.L., Radbruch, H., Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Scheibenbogen, C., Dengler, N.F. and Stenzel, W.
Acta Neuropathologica Communications 11
(1): 193.
8 December 2023
Immune phenotypes and checkpoint molecule expression of clonally expanded lymph node-infiltrating T cells in classical Hodgkin lymphoma.
Ballhausen, A. ORCID: https://orcid.org/0000-0002-5470-4973, Ben Hamza, A., Welters, C., Dietze, K., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rahn, H.P. ORCID: https://orcid.org/0000-0002-5233-3937, Hartmann, S., Hansmann, M.L. and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
Cancer Immunology Immunotherapy 72
(2): 515-521.
February 2023
Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR.
Balyschew, N., Yushkevich, A. ORCID: https://orcid.org/0000-0002-8729-9281, Mikirtumov, V. ORCID: https://orcid.org/0009-0004-6849-4825, Sanchez, R.M., Sprink, T. ORCID: https://orcid.org/0000-0002-0760-6828 and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
Nature Communications 14
(1): 6543.
17 October 2023
Unwelcome guests – the role of gland-associated Helicobacter pylori infection in gastric carcinogenesis.
Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Frontiers in Oncology 13
: 1171003.
21 April 2023
Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M., Terkelsen, T., Bartels, A.S., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G.I., Fang, X., Mann, M. and Moreira, J.M.A.
Gastroenterology 165
(1): 121-132.e5.
July 2023
Establishment and thorough characterization of xenograft (PDX) models derived from patients with pancreatic cancer for molecular analyses and chemosensitivity testing.
Behrens, D., Pfohl, U. ORCID: https://orcid.org/0000-0001-7203-2712, Conrad, T., Becker, M., Brzezicha, B., Büttner, B., Wagner, S. ORCID: https://orcid.org/0009-0002-5756-8046, Hallas, C., Lawlor, R., Khazak, V., Linnebacher, M. ORCID: https://orcid.org/0000-0001-8054-1402, Wartmann, T., Fichtner, I., Hoffmann, J., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283 and Walther, W.
Cancers 15
(24): 5753.
8 December 2023
Leveraging large language models for decision support in personalized oncology.
Benary, M. ORCID: https://orcid.org/0000-0002-3067-2030, Wang, X.D., Schmidt, M., Soll, D., Hilfenhaus, G. ORCID: https://orcid.org/0000-0001-8764-077X, Nassir, M., Sigler, C., Knödler, M., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Keilholz, U., Leser, U. and Rieke, D.T.
JAMA Network Open 6
(11): e2343689.
November 2023
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia.
Beneyto-Calabuig, S., Merbach, A.K., Kniffka, J.A., Antes, M., Szu-Tu, C., Rohde, C., Waclawiczek, A., Stelmach, P., Gräßle, S. ORCID: https://orcid.org/0000-0002-5260-6392, Pervan, P., Janssen, M., Landry, J.J.M., Benes, V., Jauch, A., Brough, M., Bauer, M., Besenbeck, B., Felden, J., Bäumer, S., Hundemer, M., Sauer, T., Pabst, C., Wickenhauser, C., Angenendt, L., Schliemann, C., Trumpp, A., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Scherer, M., Raffel, S., Müller-Tidow, C. and Velten, L.
Cell Stem Cell 30
(5): 706-721.
4 May 2023
The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing.
Bischoff, N., Wimberger, S., Kuehn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Laugesen, A., Turan, V., Larsen, B.D., Sørensen, C.S., Helin, K., Bennett, E.P., Maresca, M. and Brakebusch, C.
Gene and Genome Editing 5
: 100023.
June 2023
Systemic inflammation and normocytic anemia in DOCK11 deficiency.
Block, J., Rashkova, C., Castanon, I., Zoghi, S., Platon, J., Ardy, R.C., Fujiwara, M., Chaves, B., Schoppmeyer, R., van der Made, C.I., Jimenez Heredia, R., Harms, F.L., Alavi, S., Alsina, L., Sanchez Moreno, P., Ávila Polo, R., Cabrera-Pérez, R., Kostel Bal, S., Pfajfer, L., Ransmayr, B., Mautner, A.K., Kondo, R., Tinnacher, A., Caldera, M., Schuster, M., Domínguez Conde, C., Platzer, R., Salzer, E., Boyer, T., Brunner, H.G., Nooitgedagt-Frons, J.E., Iglesias, E., Deyà-Martinez, A., Camacho-Lovillo, M., Menche, J., Bock, C., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Pickl, W.F., Distel, M., Yoder, J.A., Traver, D., Engelhardt, K.R., Linden, T., Kager, L., Hannich, J.T., Hoischen, A., Hambleton, S., Illsinger, S., Da Costa, L., Kutsche, K., Chavoshzadeh, Z., van Buul, J.D., Antón, J., Calzada-Hernández, J., Neth, O., Viaud, J., Nishikimi, A., Dupré, L. and Boztug, K.
New England Journal of Medicine 389
(6): 527-539.
10 August 2023
Combining metabolic pulse labeling and quantitative proteomics to monitor protein synthesis upon viral infection.
Bogdanow, B. ORCID: https://orcid.org/0000-0002-9634-7353, Katsimani, N., Liu, F. and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Methods in Molecular Biology 2610
: 149-165.
2023
Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors.
Bonifacius, A. ORCID: https://orcid.org/0000-0002-0112-967X, Lamottke, B., Tischer-Zimmermann, S., Schultze-Florey, R., Goudeva, L., Heuft, H.G., Arseniev, L., Beier, R., Beutel, G. ORCID: https://orcid.org/0000-0001-6758-6104, Cario, G., Fröhlich, B., Greil, J. ORCID: https://orcid.org/0000-0003-1821-1183, Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128, Hasenkamp, J., Höfs, M., Hundsdoerfer, P., Jost, E., Kafa, K., Kriege, O., Kröger, N. ORCID: https://orcid.org/0000-0001-5103-9966, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Meisel, R. ORCID: https://orcid.org/0000-0001-5230-0628, Nathrath, M., Putkonen, M., Ravens, S., Reinhardt, H.C., Sala, E., Sauer, M.G, Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Schroers, R. ORCID: https://orcid.org/0000-0003-2744-5491, Steckel, N.K., Trappe, R.U. ORCID: https://orcid.org/0000-0001-7565-7160, Verbeek, M., Wolff, D. ORCID: https://orcid.org/0000-0001-7015-3190, Blasczyk, R. ORCID: https://orcid.org/0000-0003-3875-3190, Eiz-Vesper, B. and Maecker-Kolhoff, B. ORCID: https://orcid.org/0000-0001-8164-514X
Journal of Clinical Investigation 133
(12): e163548.
15 June 2023
Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy.
Boogerd, C.J. ORCID: https://orcid.org/0000-0002-7119-5381, Lacraz, G.P.A. ORCID: https://orcid.org/0000-0002-0373-3256, Vértesy, Á. ORCID: https://orcid.org/0000-0001-6075-5702, van Kampen, S.J. ORCID: https://orcid.org/0000-0002-4146-8481, Perini, I., de Ruiter, H., Versteeg, D., Brodehl, A. ORCID: https://orcid.org/0000-0001-9202-2343, van der Kraak, P., Giacca, M. ORCID: https://orcid.org/0000-0003-2927-7225, de Jonge, N., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290, van Oudenaarden, A. ORCID: https://orcid.org/0000-0002-9442-3551, Vink, A. ORCID: https://orcid.org/0000-0002-9371-8788 and van Rooij, E. ORCID: https://orcid.org/0000-0002-2026-9408
Cardiovascular Research 119
(2): 477-491.
February 2023
Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness.
Breun, M., Flock, K., Feldheim, J. ORCID: https://orcid.org/0000-0002-7297-4854, Nattmann, A., Monoranu, C.M., Herrmann, P., Ernestus, R.I., Löhr, M., Hagemann, C. ORCID: https://orcid.org/0000-0001-9759-8149 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cancers 15
(16): 4089.
14 August 2023
Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F. ORCID: https://orcid.org/0000-0001-5969-9467, Noerenberg, D., Hennch, C. ORCID: https://orcid.org/0000-0003-4104-5531, Yoshida, K. ORCID: https://orcid.org/0000-0003-4612-2778, Hablesreiter, R. ORCID: https://orcid.org/0000-0002-4586-932X, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Sasca, D. ORCID: https://orcid.org/0000-0003-0330-7959, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Mansouri, L., Inoue, Y., Wiegand, L. ORCID: https://orcid.org/0000-0002-9917-7396, Staiger, A.M. ORCID: https://orcid.org/0000-0002-5896-3200, Casadei, B., Korkolopoulou, P., Weiner, J. ORCID: https://orcid.org/0000-0003-1438-7819, Lopez-Guillermo, A., Warth, A., Schneider, T., Nagy, Á. ORCID: https://orcid.org/0000-0001-6118-0365, Klapper, W., Hummel, M. ORCID: https://orcid.org/0000-0001-6717-605X, Kanellis, G., Anagnostopoulos, I. ORCID: https://orcid.org/0000-0002-5043-6043, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rosenquist, R. ORCID: https://orcid.org/0000-0002-0211-8788, Vassilakopoulos, T.P., Ott, G., Ogawa, S. ORCID: https://orcid.org/0000-0002-7778-5374 and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 37
(11): 2237-2249.
November 2023
Nivolumab and doxorubicin, vinblastine, and dacarbazine in early-stage unfavorable Hodgkin Lymphoma: final analysis of the randomized german Hodgkin study group phase II NIVAHL trial.
Bröckelmann, P.J. ORCID: https://orcid.org/0000-0001-9662-9900, Bühnen, I., Meissner, J., Trautmann-Grill, K. ORCID: https://orcid.org/0000-0002-9050-1049, Herhaus, P., Halbsguth, T.V., Schaub, V., Kerkhoff, A. ORCID: https://orcid.org/0000-0001-6904-2821, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Bormann, M., Dickhut, A., Kaul, H., Fuchs, M. ORCID: https://orcid.org/0000-0003-3289-3272, Kobe, C. ORCID: https://orcid.org/0000-0002-2909-0826, Baues, C. ORCID: https://orcid.org/0000-0003-1733-6064, Borchmann, P. ORCID: https://orcid.org/0000-0003-3782-2158, Engert, A. ORCID: https://orcid.org/0000-0002-1890-1523 and von Tresckow, B. ORCID: https://orcid.org/0000-0003-1410-4487
Journal of Clinical Oncology 41
(6): 1193-1199.
20 February 2023
The recurrent atypical e8a2 BCR::ABL1 transcript with insertion of an inverted 55 base pair ABL1 intron 1b sequence: a detailed molecular analysis.
Burmeister, T., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and le Coutre, P.
Acta Haematologica 146
(5): 413-418.
October 2023
Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.
Burmeister, T., Gröger, D., Gökbuget, N., Spriewald, B., Starck, M., Elmaagacli, A., Hoelzer, D., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Schwartz, S.
Scientific Reports 13
(1): 15167.
13 September 2023
Inferior outcomes of EU versus US patients treated with CD19 CAR-T for relapsed/refractory large B-cell lymphoma: association with differences in tumor burden, systemic inflammation, bridging therapy utilization, and CAR-T product use.
Bücklein, V., Perez, A., Rejeski, K., Iacoboni, G., Jurinovic, V., Holtick, U., Penack, O., Kharboutli, S., Blumenberg, V., Ackermann, J., Frölich, L., Johnson, G., Patel, K., Arciola, B., Mhaskar, R., Wood, A., Schmidt, C., Albanyan, O., Gödel, P., Hoster, E., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mackensen, A., Locke, F., von Bergwelt, M., Barba, P., Subklewe, M. and Jain, M.D.
HemaSphere 7
(8): e907.
August 2023
The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity.
Carriquí-Madroñal, B. ORCID: https://orcid.org/0000-0002-0640-3041, Sheldon, J., Duven, M., Stegmann, C., Cirksena, K., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Zapatero-Belinchón, F.J., Vondran, F.W.R. and Gerold, G. ORCID: https://orcid.org/0000-0002-1326-5038
PLoS Pathogens 19
(11): e1011759.
15 November 2023
scEC(&)T-seq: a method for parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single human cells.
Chamorro González, Rocío ORCID: https://orcid.org/0000-0002-5653-7259, Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Kasack, Katharina and Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X
Research Square.
23 May 2023
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Stöber, M.C. ORCID: https://orcid.org/0000-0002-6679-5577, Xu, R. ORCID: https://orcid.org/0000-0002-5618-246X, Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Kasack, K., Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, van Leen, E. ORCID: https://orcid.org/0000-0001-9545-4803, Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Stefanova, M.E. ORCID: https://orcid.org/0000-0002-4419-2839, Hung, K.L. ORCID: https://orcid.org/0000-0002-3662-4662, Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Schmelz, K., Lodrini, M., Mundlos, S., Chang, H.Y. ORCID: https://orcid.org/0000-0002-9459-4393, Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Koche, R.P. ORCID: https://orcid.org/0000-0002-6820-5083 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Nature Genetics 55
(5): 880-890.
May 2023
Disentangling extrachromosomal circular DNA heterogeneity in single cells with scEC&T-seq.
Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Nature Genetics 55
(5): 740-741.
May 2023
Determining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging.
Chang, S.Y.S. ORCID: https://orcid.org/0000-0002-5627-9106, Dijkman, P.M., Wiessing, S.A. and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
Scientific Reports 13
: 11523.
17 July 2023
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Chee, J.M., Lanoue, L., Clary, D., Higgins, K., Bower, L., Flenniken, A., Guo, R., Adams, D.J., Bosch, F., Braun, R.E., Brown, S.D.M., Chin, H.J.G., Dickinson, M.E., Hsu, C.W., Dobbie, M., Gao, X., Galande, S., Grobler, A., Heaney, J.D., Herault, Y., de Angelis, M.H., Mammano, F., Nutter, L.M.J, Parkinson, H., Qin, C., Shiroishi, T., Sedlacek, R., Seong, J.K., Xu, Y., Brooks, B., McKerlie, C., Lloyd, K.C.K., Westerberg, H. and Moshiri, A.
BMC Biology 21
(1): 22.
3 February 2023
Mechanisms of substrate processing during ER-associated protein degradation.
Christianson, J.C., Jarosch, E. ORCID: https://orcid.org/0000-0002-5897-3492 and Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202
Nature Reviews Molecular Cell Biology 24
(11): 777-796.
November 2023
Gentle ions for cryo-FIB milling.
Chu, X. ORCID: https://orcid.org/0000-0001-6801-3949 and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
Structure 31
(10): 1147-1148.
5 October 2023
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Danielli, S.G. ORCID: https://orcid.org/0000-0003-3101-3114, Porpiglia, E. ORCID: https://orcid.org/0000-0003-2652-899X, De Micheli, A.J. ORCID: https://orcid.org/0000-0002-9985-2638, Navarro, N. ORCID: https://orcid.org/0000-0002-2160-6656, Zellinger, M.J., Bechtold, I., Kisele, S. ORCID: https://orcid.org/0000-0003-0369-7854, Volken, L., Marques, J.G. ORCID: https://orcid.org/0000-0001-7152-9655, Kasper, S. ORCID: https://orcid.org/0000-0003-2698-0206, Bode, P.K. ORCID: https://orcid.org/0000-0002-9633-4042, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Delattre, O., Surdez, D. ORCID: https://orcid.org/0000-0002-7118-7859, Roma, J. ORCID: https://orcid.org/0000-0001-7692-6123, Bühlmann, P. ORCID: https://orcid.org/0000-0002-1782-6015, Blau, H.M. ORCID: https://orcid.org/0000-0001-6503-5480, Wachtel, M. and Schäfer, B.W. ORCID: https://orcid.org/0000-0001-5988-2915
Science Advances 9
(6): eade9238.
10 February 2023
Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture.
Dasgupta, S., Dayagi, D.Y., Haimovich, G., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Olender, T., Singer, R.H., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Gerst, J.E.
eLife 12
: e83584.
30 May 2023
Turning science into cover art.
Dauben, H., Matic, I., Kidmose, R.T., Pedersen, B.P., Saha, T., Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793 and Sung, J.H.
Trends in Biochemical Sciences 48
(12): 1009-1011.
December 2023
Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response.
Deimel, L.P., Xue, X., Khan, A., Moynie, L., Buchanan, C.J., Sun, G., McBride, R., Schuster, H., Gauthier, C., Saliba, R., Leonavicus, K., Minall, L., Bort, G., Russell, R.A., Sezgin, E., Paulson, J.C., Anthony, D.C., Baldwin, A.J., Naismith, J., Schiffner, T., Davis, B.G. and Sattentau, Q.J. ORCID: https://orcid.org/0000-0001-7170-1937
bioRxiv
: 2023.06.03.543556.
6 June 2023
Small molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy.
Demel, U.M. ORCID: https://orcid.org/0000-0002-6480-4185, Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Zhang, L., Isaakidis, K., Dönig, J., Böger, M. ORCID: https://orcid.org/0000-0001-9301-5022, Singh, N., Köse, H., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Müller, S., Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611 and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Haematologica 108
(2): 555-567.
February 2023
Mucosa-associated microbiota alterations in primary sclerosing cholangitis (PSC) before and after liver transplantation—who is calling the shots?
Demir, M. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Hepatobiliary Surgery and Nutrition 12
(5): 795-797.
1 October 2023
Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.
Denkinger, C.M., Janssen, M., Schäkel, U., Gall, J., Leo, A., Stelmach, P., Weber, S.F., Krisam, J., Baumann, L., Stermann, J., Merle, U., Weigand, M.A., Nusshag, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schrezenmeier, J.F., Bornhäuser, M., Alakel, N., Witzke, O., Wolf, T., Vehreschild, M.J.G.T., Schmiedel, S., Addo, M.M., Herth, F., Kreuter, M., Tepasse, P.R., Hertenstein, B., Hänel, M., Morgner, A., Kiehl, M., Hopfer, O., Wattad, M.A., Schimanski, C.C., Celik, C., Pohle, T., Ruhe, M., Kern, W.V., Schmitt, A., Lorenz, H.M., Souto-Carneiro, M., Gaeddert, M., Halama, N., Meuer, S., Kräusslich, H.G., Müller, B., Schnitzler, P., Parthé, S., Bartenschlager, R., Gronkowski, M., Klemmer, J., Schmitt, M., Dreger, P., Kriegsmann, K., Schlenk, Ri.F. and Müller-Tidow, C.
Nature Cancer 4
(1): 96-107.
January 2023
HMGXB4 targets Sleeping Beauty transposition to germinal stem cells.
Devaraj, A. ORCID: https://orcid.org/0000-0002-8685-6728, Singh, M. ORCID: https://orcid.org/0000-0002-8626-5418, Narayanavari, S.A. ORCID: https://orcid.org/0000-0002-6997-4829, Yong, G. ORCID: https://orcid.org/0009-0003-3975-0474, Chen, J. ORCID: https://orcid.org/0000-0002-3671-553X, Wang, J. ORCID: https://orcid.org/0000-0002-7027-0298, Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z. ORCID: https://orcid.org/0000-0002-6574-2588, Raskó, T., Radscheit, K., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658 and Izsvak, Z. ORCID: https://orcid.org/0000-0002-2053-2384
International Journal of Molecular Sciences 24
(8): 7283.
14 April 2023
Retained functional normal and preleukemic HSCs at diagnosis are associated to good prognosis in DNMT3Amut NPM1mut AMLs.
Donato, E., Correia, N.C., Andresen, C., Karpova, D., Würth, R., Klein, C., Sohn, M., Przybylla, A., Zeisberger, P., Rothfelder, K., Salih, H.R., Bonig, H., Stasik, S., Röllig, C., Dolnik, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Buchholz, F., Thiede, C.D., Hübschmann, D. and Trumpp, A.
Blood Advances 7
(6): 1011-1018.
28 March 2023
N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness.
Dong, Hongliang, Zeng, Lili, Chen, Weiwei, Zhang, Qian, Wang, Fei, Wu, Yan, Cui, Bingjie, Qi, Jingjing, Zhang, Xin, Liu, Cuilan, Deng, Jiong, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Du, Jing ORCID: https://orcid.org/0000-0002-2990-3575
Cell Death Discovery 9
(1): 149.
6 May 2023
Targeting B cells and microglia in multiple sclerosis with Bruton tyrosine kinase inhibitors: a review.
Dybowski, S., Torke, S. ORCID: https://orcid.org/0000-0002-1029-3623 and Weber, M.S.
JAMA Neurology 80
(4): 404-414.
1 April 2023
Diverse effects of obesity on antitumor immunity and immunotherapy.
Dyck, L. ORCID: https://orcid.org/0000-0002-2548-9039 and Lynch, L.
Trends in Molecular Medicine 29
(2): 112-123.
February 2023
Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Kühn, M.W.M., Schroeder, T., Mayer, K., Lübbert, M., Wattad, M., Götze, K., Fransecky, L., Koller, E., Wulf, G., Schleicher, J., Ringhoffer, M., Greil, R., Hertenstein, B., Krauter, J., Martens, U.M., Nachbaur, D., Samra, M.A., Machherndl-Spandl, S., Basara, N., Leis, C., Schrade, A., Kapp-Schwoerer, S., Cocciardi, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Thol, F., Heuser, M., Paschka, P., Gaidzik, V.I., Saadati, M., Benner, A., Schlenk, R.F., Döhner, K. and Ganser, A.
Lancet Haematology 10
(7): e495-e509.
July 2023
Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Dönig, J., Mende, H., Davila Gallesio, J., Wagner, K., Hotz, P. ORCID: https://orcid.org/0000-0002-3710-6840, Schunck, K., Piller, T. ORCID: https://orcid.org/0000-0001-8545-2089, Hölper, S., Uhan, S., Kaulich, M. ORCID: https://orcid.org/0000-0002-9528-8822, Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Tascher, G. ORCID: https://orcid.org/0000-0002-5907-3947, Bohnsack, K.E. ORCID: https://orcid.org/0000-0001-6035-4255 and Müller, S. ORCID: https://orcid.org/0000-0002-8792-7700
Nature Communications 14
(1): 8121.
8 December 2023
Genome-engineering technologies for modeling and treatment of cystic fibrosis.
Dębczyński, M., Mojsak, D., Minarowski, Ł., Maciejewska, M., Mróz, R.M. and Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072
Advances in Medical Sciences 68
(1): 111-120.
March 2023
Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert, T., Hsu, C.J., Becker, A.L., Graessle, S. ORCID: https://orcid.org/0000-0002-5260-6392, Horne, A. ORCID: https://orcid.org/0000-0002-4209-4573, Bemmann, F. ORCID: https://orcid.org/0009-0007-0533-7138, Zhang, Q., Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Vasioukhin, V., Scholl, S., Hochhaus, A. ORCID: https://orcid.org/0000-0003-0626-0834, Siegerist, F., Endlich, N., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Schnoeder, T.M and Heidel, F.H. ORCID: https://orcid.org/0000-0003-2438-1955
Leukemia 37
(10): 2027-2035.
October 2023
Parallel in-depth analysis of repeat expansions in ataxia patients by long-read sequencing.
Erdmann, H., Schöberl, F., Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Leal Silva, R.M., Scholz, V., Scharf, F., Wendlandt, M., Kleinle, S., Deschauer, M., Nübling, G., Heide, W., Babacan, S.S., Schneider, C., Neuhann, T., Hahn, K., Schoser, B., Holinski-Feder, E., Wolf, D.A. and Abicht, A. ORCID: https://orcid.org/0000-0002-2757-8131
Brain 146
(5): 1831-1843.
May 2023
Predictors of lower exercise capacity in patients with cancer.
Evertz, R. ORCID: https://orcid.org/0000-0002-5904-4652, Diehl, C., Gödde, K., Valentova, M., Garfias-Veitl, T., Overbeck, T.R., Braulke, F., Lena, A., Hadzibegovic, S., Bleckmann, A., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Landmesser, U., König, A.O., Hasenfuss, G., Schuster, A. ORCID: https://orcid.org/0000-0003-1508-1125, Anker, M.S. and von Haehling, S.
Scientific Reports 13
(1): 14861.
8 September 2023
Cardiovascular and metabolic determinants of quality of life in patients with cancer.
Evertz, R. ORCID: https://orcid.org/0000-0002-5904-4652, Gödde, K., Diehl, C., Valentova, M., Garfias-Veitl, T., Braulke, F., Wulf, G.G., Overbeck, T.R., Bleckmann, A., König, A.O., Weinländer, P., Potthoff, S., Hadzibegovic, S., Lena, A., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Landmesser, U., Schuster, A. ORCID: https://orcid.org/0000-0003-1508-1125, Anker, M.S., Hasenfuß, G. and von Haehling, S. ORCID: https://orcid.org/0000-0002-9818-042X
ESC Heart Failure 10
(1): 167-176.
February 2023
IL-33 expression is lower in current smokers at both transcriptomic and protein level.
Faiz, A. ORCID: https://orcid.org/0000-0003-1740-3538, Mahbub, R.M., Boedijono, F.S., Tomassen, M.I., Kooistra, W., Timens, W., Nawijn, M., Hansbro, P.M., Johansen, M.D., Pouwels, S.D. ORCID: https://orcid.org/0000-0001-7345-8061, Heijink, I.H., Massip, F. ORCID: https://orcid.org/0000-0001-5855-0935, de Biase, M.S. ORCID: https://orcid.org/0000-0003-0383-5161, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Adcock, I.M. ORCID: https://orcid.org/0000-0003-2101-8843, Chung, K.F., van der Does, A., Hiemstra, P.S., Goulaouic, H., Xing, H., Abdulai, R., de Rinaldis, E., Cunoosamy, D., Harel, S., Lederer, D., Nivens, M.C., Wark, P.A. ORCID: https://orcid.org/0000-0001-5676-6126, Kerstjens, H.A.M., Hylkema, M.N., Brandsma, C.A. and van den Berge, M.
American Journal of Respiratory and Critical Care Medicine 208
(10): 1075-1087.
15 November 2023
Thioester and oxyester linkages in the ubiquitin system.
Ferri-Blazquez, A. ORCID: https://orcid.org/0000-0002-4533-5117, Jarosch, E. ORCID: https://orcid.org/0000-0002-5897-3492 and Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202
Methods in Molecular Biology 2602
: 3-18.
2023
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Cui, C., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Del Bel, K.L., Eibel, H., Feng, X., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Gebhardt, J.C.M., Götz, A., Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Xiong, E. ORCID: https://orcid.org/0000-0001-5124-6922, Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Rosenzweig, S.D., Schwarz, K., Turvey, S.E. and Wang, J.Y.
Science Immunology 8
(79): eade7953.
January 2023
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Frankell, A.M., Dietzen, M., Al Bakir, M., Lim, E.L., Karasaki, T., Ward, S., Veeriah, S., Colliver, E., Huebner, A., Bunkum, A., Hill, M.S., Grigoriadis, K., Moore, D.A., Black, J.R.M., Liu, W.K., Thol, K., Pich, O., Watkins, T.B.K., Naceur-Lombardelli, C., Cook, D.E., Salgado, R., Wilson, G.A., Bailey, C., Angelova, M., Bentham, R., Martínez-Ruiz, C., Abbosh, C., Nicholson, A.G., Le Quesne, J., Biswas, D., Rosenthal, R., Puttick, C., Hessey, S., Lee, C., Prymas, P., Toncheva, A., Smith, J., Xing, W., Nicod, J., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Blyth, K.G., Fennell, D.A., Forster, M.D., Lee, S.M., Falzon, M., Hewish, M., Shackcloth, M.J., Lim, E., Benafif, S., Russell, P., Boleti, E., Krebs, M.G., Lester, J.F., Papadatos-Pastos, D., Ahmad, T., Thakrar, R.M., Lawrence, D., Navani, N., Janes, S.M., Dive, C., Blackhall, F.H, Summers, Y., Cave, J., Marafioti, T., Herrero, J., Quezada, S.A., Peggs, K.S., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Van Loo, P., Miedema, D.M., Birkbak, N.J., Hiley, C.T., Hackshaw, A., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
(7957): 525-533.
20 April 2023
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
Franz, A. ORCID: https://orcid.org/0000-0003-0562-6451, Weber, A.I. ORCID: https://orcid.org/0000-0001-5103-6060, Preußner, M. ORCID: https://orcid.org/0000-0001-5155-0844, Dimos, N. ORCID: https://orcid.org/0000-0001-5398-7310, Stumpf, A. ORCID: https://orcid.org/0000-0002-1510-6970, Ji, Y., Moreno-Velasquez, L. ORCID: https://orcid.org/0000-0001-9735-0039, Voigt, A., Schulz, F. ORCID: https://orcid.org/0000-0002-7756-0562, Neumann, A., Kuropka, B. ORCID: https://orcid.org/0000-0001-5088-6346, Kuehn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Urlaub, H., Schmitz, D. ORCID: https://orcid.org/0000-0003-2741-5241, Wahl, M.C. ORCID: https://orcid.org/0000-0002-2811-5307 and Heyd, F. ORCID: https://orcid.org/0000-0001-9377-9882
Life Science Alliance 6
(3): e202201826.
March 2023
CAR links hypoxia signaling to improved survival after myocardial infarction.
Freiberg, F., Thakkar, M., Hamann, W., Lopez Carballo, J. ORCID: https://orcid.org/0000-0002-7735-7185, Jüttner, R. ORCID: https://orcid.org/0000-0003-3565-0698, Voss, F.K., Becher, P.M., Westermann, D., Tschöpe, C., Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Rocks, O. ORCID: https://orcid.org/0000-0001-6349-9193, Fischer, R. and Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172
Experimental and Molecular Medicine 55
(3): 643-652.
March 2023
Iterative Bleaching Extends Multiplexity (IBEX) Knowledge-Base.
Fritzsche, Sonja ORCID: https://orcid.org/0000-0003-3335-3534
[Dataset]
3 March 2023
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S. ORCID: https://orcid.org/0000-0001-9619-4329, Danßmann, C., Klironomos, F., Winkler, A., Fallmann, J. ORCID: https://orcid.org/0000-0002-4573-9939, Kruetzfeldt, L.M. ORCID: https://orcid.org/0000-0003-3630-3727, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Naderi, J., Bernhart, S.H. ORCID: https://orcid.org/0000-0002-5928-9449, Grunewald, L., Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997, Suenkel, C. ORCID: https://orcid.org/0000-0002-5326-6043, Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Meggetto, F. ORCID: https://orcid.org/0000-0002-2610-0144, Remke, M. ORCID: https://orcid.org/0000-0002-9404-9993, Stadler, P.F., Hundsdoerfer, P., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412, Lang, P. ORCID: https://orcid.org/0000-0001-7737-2142, Fuchs, J., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516 and Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201
Nature Communications 14
(1): 3936.
4 July 2023
Protein biomarkers in blood reflect the interrelationships between stroke outcome, inflammation, coagulation, adhesion, senescence and cancer.
Fuellen, G. ORCID: https://orcid.org/0000-0002-4994-9829, Walter, U., Henze, L., Böhmert, J., Palmer, D., Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Rudolf, H. and Kowald, A.
Cellular and Molecular Neurobiology 43
(4): 1413-1424.
May 2023
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice.
Funk, M.C. ORCID: https://orcid.org/0000-0002-6007-1164, Gleixner, J.G., Heigwer, F., Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Valentini, E., Aydin, Z., Tonin, E., Del Prete, S., Mahara, S., Throm, Y., Hetzer, J., Heide, D., Stegle, O., Odom, D.T., Feldmann, A., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Heikenwalder, M. and Boutros, M. ORCID: https://orcid.org/0000-0002-9458-817X
Developmental Cell 58
(24): 2914-2929.
18 December 2023
Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes.
Gainullina, A. ORCID: https://orcid.org/0000-0003-3796-2337, Mogilenko, D.A., Huang, L.H., Todorov, H., Narang, V., Kim, K.W., Yng, L.S., Kent, A., Jia, B., Seddu, K., Krchma, K., Wu, J., Crozat, K. ORCID: https://orcid.org/0000-0003-4761-3675, Tomasello, E., Dress, R., See, P., Scott, C., Gibbings, S., Bajpai, G., Desai, J.V. ORCID: https://orcid.org/0000-0002-8823-0796, Maier, B., This, S., Wang, P., Aguilar, S.V., Poupel, L., Dussaud, S., Zhou, T.A., Angeli, V., Blander, J.M., Choi, K. ORCID: https://orcid.org/0000-0002-9634-9375, Dalod, M., Dzhagalov, I., Gautier, E.L., Jakubzick, C., Lavine, K., Lionakis, M.S., Paidassi, H., Sieweke, M.H. ORCID: https://orcid.org/0000-0002-3228-9537, Ginhoux, F., Guilliams, M., Benoist, C., Merad, M., Randolph, G.J., Sergushichev, A. ORCID: https://orcid.org/0000-0003-1159-7220 and Artyomov, M.N. ORCID: https://orcid.org/0000-0002-1133-4212
Cell Reports 42
(2): 112046.
28 February 2023
Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and expansion of cTfh1 cells and impaired B memory cell formation.
Garner-Spitzer, E. ORCID: https://orcid.org/0000-0002-5283-0458, Wagner, A., Gudipati, V., Schoetta, A.M., Orola-Taus, M., Kundi, M., Kunert, R., Mayrhofer, P., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Stockinger, H., Carsetti, R., Gattinger, P., Valenta, R., Kratzer, B. ORCID: https://orcid.org/0000-0003-1091-4327, Sehgal, A.N.A., Pickl, W.F., Reinisch, W., Novacek, G. and Wiedermann, U. ORCID: https://orcid.org/0000-0002-1302-3223
EBioMedicine 96
: 104788.
October 2023
Personalizing precision medicine: Patients with AML perceptions about treatment decisions.
Grauman, A., Kontro, M., Haller, K., Nier, S., Aakko, S., Lang, K., Zingaretti, C., Meggiolaro, E., De Padova, S., Marconi, G., Martinelli, G., Heckman, C.A., Simonetti, G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Kihlbom, U.
Patient Education and Counseling 115
: 107883.
5 July 2023
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
Griger, J., Widholz, S.A., Jesinghaus, M., de Andrade Krätzig, N., Lange, S., Engleitner, T., Montero, J.J., Zhigalova, E., Öllinger, R., Suresh, V., Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Lier, S., Baranov, O., Trozzo, R., Ben Khaled, N., Chakraborty, S., Yu, J., Konukiewitz, B., Steiger, K., Pfarr, N., Rajput, A., Sailer, D., Keller, G., Schirmacher, P., Röcken, C., Fagerstedt, K.W., Mayerle, J., Schmidt-Supprian, M., Schneider, G., Weichert, W., Calado, D.P. ORCID: https://orcid.org/0000-0001-8239-7184, Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Klöppel, G., Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Saur, D. and Rad, R.
Cancer Cell 41
(7): 1327-1344.e10.
10 July 2023
Recombination between heterologous human acrocentric chromosomes.
Guarracino, A., Buonaiuto, S., de Lima, L.G., Potapova, T., Rhie, A., Koren, S., Rubinstein, B., Fischer, C., Gerton, J.L., Phillippy, A.M., Colonna, V. and Garrison, E.
Nature 617
(7960): 335-343.
11 May 2023
Single-cell RNA sequencing data of human lymph node samples generated with BD Rhapsody.
Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Dietrich, Sascha and Hübschmann, Daniel
[Dataset]
10 February 2023
Hand grip strength in patients with advanced cancer: a prospective study.
Hadzibegovic, S., Porthun, J., Lena, A., Weinlaänder, P., Lück, L.C., Potthoff, S.K., Rösnick, L., Fröhlich, A.K., Ramer, L.V., Sonntag, F., Wilkenshoff, U., Ahn, J., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mahabadi, A.A., Totzeck, M., Rassaf, T., von Haehling, S., Coats, A.J.S., Anker, S.D., Roeland, E.J., Landmesser, U. and Anker, M.S. ORCID: https://orcid.org/0000-0002-4406-8555
Journal of Cachexia Sarcopenia and Muscle 14
(4): 1682-1694.
August 2023
Transcription factor induction of vascular blood stem cell niches in vivo.
Hagedorn, E.J., Perlin, J.R., Freeman, R.J., Wattrus, S.J., Han, T., Mao, C., Kim, J.W., Fernández-Maestre, I., Daily, M.L., D'Amato, C., Fairchild, M.J., Riquelme, R., Li, B., Ragoonanan, D.A.V.E., Enkhbayar, K., Henault, E.L., Wang, H.G., Redfield, S.E., Collins, S.H., Lichtig, A., Yang, S., Zhou, Y., Kunar, B., Gomez-Salinero, J.M., Dinh, T.T., Pan, J., Holler, K. ORCID: https://orcid.org/0000-0002-5159-9223, Feldman, H.A., Butcher, E.C., van Oudenaarden, A., Rafii, S., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Zon, L.I. ORCID: https://orcid.org/0000-0003-0860-926X
Developmental Cell 58
(12): 1037-1051.
19 June 2023
Single-cell multi-omics and lineage tracing to dissect cell fate decision-making.
Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170 and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
Stem Cell Reports 18
(1): 13-25.
10 January 2023
Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis.
Harnack, C., Berger, H., Liu, L., Mollenkopf, H.J., Strowig, T. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Gut Microbes 15
(1): 2233689.
10 July 2023
A DNA origami-based biointerface to interrogate the spatial requirements for sensitized T-Cell antigen recognition.
Hellmeier, J., Platzer, R., Huppa, J.B. and Sevcsik, E.
Methods in Molecular Biology 2654
: 277-302.
28 April 2023
Recent advances in precision medicine for acute myeloid leukemia.
Hernández-Sánchez, A. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Current Opinion in Oncology 35
(6): 581-588.
November 2023
SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Heynen, G.J.J.E., Baumgartner, F. ORCID: https://orcid.org/0000-0003-0768-1956, Heider, M., Patra, U., Holz, M., Braune, J., Kaiser, M., Schäffer, I., Bamopoulos, S.A., Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Murgai, A., Ng, Y.L.D., Demel, U.M. ORCID: https://orcid.org/0000-0002-6480-4185, Laue, D., Liebig, S., Krüger, J., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Nogai, A., Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Müller, S., Bassermann, F., Krönke, J., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Wirth, M.
Blood Advances 7
(4): 469-481.
28 February 2023
Lung adenocarcinoma promotion by air pollutants.
Hill, W., Lim, E.L., Weeden, C.E., Lee, C., Augustine, M., Chen, K., Kuan, F.C., Marongiu, F., Evans, E.J., Moore, D.A., Rodrigues, F.S., Pich, O., Bakker, B., Cha, H., Myers, R., van Maldegem, F., Boumelha, J., Veeriah, S., Rowan, A., Naceur-Lombardelli, C., Karasaki, T., Sivakumar, M., De, S., Caswell, D.R., Nagano, A., Black, J.R.M., Martínez-Ruiz, C., Ryu, M.H., Huff, R.D., Li, S., Favé, M.J., Magness, A., Suárez-Bonnet, A., Priestnall, S.L., Lüchtenborg, M., Lavelle, K., Pethick, J., Hardy, S., McRonald, F.E., Lin, M.H., Troccoli, C.I., Ghosh, M., Miller, Y.E., Merrick, D.T., Keith, R.L., Al Bakir, M., Bailey, C., Hill, M.S., Saal, L.H., Chen, Y., George, A.M., Abbosh, C., Kanu, N., Lee, S.H., McGranahan, N., Berg, C.D., Sasieni, P., Houlston, R., Turnbull, C., Lam, S., Awadalla, P., Grönroos, E., Downward, J., Jacks, T., Carlsten, C., Malanchi, I., Hackshaw, A., Litchfield, K., DeGregori, J., Jamal-Hanjani, M. and Swanton, C.
Nature 616
(7955): 159-167.
6 April 2023
The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies.
Hoffmann, J., Hanß, S. ORCID: https://orcid.org/0000-0002-9133-8685, Kraus, M. ORCID: https://orcid.org/0000-0003-4825-8724, Schaller, J. ORCID: https://orcid.org/0000-0002-9399-1653, Schäfer, C. ORCID: https://orcid.org/0000-0001-8873-7231, Stahl, D. ORCID: https://orcid.org/0000-0002-4283-4543, Anker, S.D. ORCID: https://orcid.org/0000-0002-0805-8683, Anton, G. ORCID: https://orcid.org/0000-0003-0483-892X, Bahls, T. ORCID: https://orcid.org/0000-0001-9150-5589, Blankenberg, S. ORCID: https://orcid.org/0000-0001-6488-2362, Blumentritt, A. ORCID: https://orcid.org/0000-0002-6068-0752, Boldt, L.H., Cordes, S., Desch, S. ORCID: https://orcid.org/0000-0002-1349-9969, Doehner, W. ORCID: https://orcid.org/0000-0001-7598-708X, Dörr, M. ORCID: https://orcid.org/0000-0001-7471-475X, Edelmann, F., Eitel, I. ORCID: https://orcid.org/0000-0002-6442-246X, Endres, M. ORCID: https://orcid.org/0000-0001-6520-3720, Engelhardt, S. ORCID: https://orcid.org/0000-0001-5378-8661, Erdmann, J. ORCID: https://orcid.org/0000-0002-4486-6231, Eulenburg, K., Falk, V. ORCID: https://orcid.org/0000-0002-7911-8620, Felix, S.B. ORCID: https://orcid.org/0000-0002-0744-091X, Frank, D. ORCID: https://orcid.org/0000-0001-7561-075X, Franke, T., Frey, N. ORCID: https://orcid.org/0000-0001-7611-378X, Friede, T. ORCID: https://orcid.org/0000-0001-5347-7441, Geidel, L., Germans, L., Grabmaier, U. ORCID: https://orcid.org/0000-0002-2168-4232, Halle, M. ORCID: https://orcid.org/0000-0003-3065-530X, Hausleiter, J. ORCID: https://orcid.org/0000-0003-2909-7961, Jakobi, V., Jebran, A.F. ORCID: https://orcid.org/0000-0003-4281-0960, Jobs, A. ORCID: https://orcid.org/0000-0002-9421-8726, Kääb, S. ORCID: https://orcid.org/0000-0001-8824-3581, Karakas, M., Katus, H.A. ORCID: https://orcid.org/0000-0002-2293-2314, Klatt, A., Knosalla, C. ORCID: https://orcid.org/0000-0002-8127-5019, Krebser, J. ORCID: https://orcid.org/0000-0002-3624-4790, Landmesser, U. ORCID: https://orcid.org/0000-0002-0214-3203, Lee, M. ORCID: https://orcid.org/0000-0001-9532-761X, Lehnert, K. ORCID: https://orcid.org/0000-0003-2342-3949, Lesser, S. ORCID: https://orcid.org/0000-0002-8104-6216, Leyh, K., Lorbeer, R. ORCID: https://orcid.org/0000-0002-2224-9208, Mach-Kolb, S., Meder, B. ORCID: https://orcid.org/0000-0003-0741-2633, Nagel, E. ORCID: https://orcid.org/0000-0002-6044-950X, Nolte, C.H. ORCID: https://orcid.org/0000-0001-5577-1775, Parwani, A.S. ORCID: https://orcid.org/0000-0003-2043-7050, Petersmann, A. ORCID: https://orcid.org/0000-0001-9843-2263, Puls, M. ORCID: https://orcid.org/0000-0001-5540-1264, Rau, H. ORCID: https://orcid.org/0000-0003-0816-0693, Reiser, M., Rienhoff, O., Scharfe, T. ORCID: https://orcid.org/0000-0001-9091-1796, Schattschneider, M., Scheel, H., Schnabel, R.B. ORCID: https://orcid.org/0000-0001-7170-9509, Schuster, A. ORCID: https://orcid.org/0000-0003-1508-1125, Schmitt, B., Seidler, T. ORCID: https://orcid.org/0000-0002-6158-5087, Seiffert, M. ORCID: https://orcid.org/0000-0002-3940-9079, Stähli, B.E., Stas, A., Stocker, T.J. ORCID: https://orcid.org/0000-0003-1162-2502, von Stülpnagel, L. ORCID: https://orcid.org/0000-0003-2238-2815, Thiele, H. ORCID: https://orcid.org/0000-0002-0169-998X, Wachter, R. ORCID: https://orcid.org/0000-0003-2231-2200, Wakili, R. ORCID: https://orcid.org/0000-0002-6326-1537, Weis, T., Weitmann, K. ORCID: https://orcid.org/0000-0003-0386-283X, Wichmann, H.E. ORCID: https://orcid.org/0000-0002-1721-3796, Wild, P. ORCID: https://orcid.org/0000-0003-4413-9752, Zeller, T. ORCID: https://orcid.org/0000-0003-3379-2641, Hoffmann, W. ORCID: https://orcid.org/0000-0002-6359-8797, Zeisberg, E.M. ORCID: https://orcid.org/0000-0001-5184-0497, Zimmermann, W.H. ORCID: https://orcid.org/0000-0003-1190-4040, Krefting, D. ORCID: https://orcid.org/0000-0002-7238-5339, Kühne, T., Peters, A. ORCID: https://orcid.org/0000-0001-6645-0985, Hasenfuß, G. ORCID: https://orcid.org/0000-0002-5942-361X, Massberg, S. ORCID: https://orcid.org/0000-0001-7387-3986, Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202, Dimmeler, S. ORCID: https://orcid.org/0000-0002-1045-2436, Eschenhagen, T. ORCID: https://orcid.org/0000-0003-1750-1170 and Nauck, M. ORCID: https://orcid.org/0000-0002-6678-7964
Clinical Research in Cardiology 112
(7): 923-941.
July 2023
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
Horkova, V. ORCID: https://orcid.org/0000-0002-3679-2236, Drobek, A. ORCID: https://orcid.org/0000-0003-1066-9413, Paprckova, D. ORCID: https://orcid.org/0000-0002-0151-4797, Niederlova, V. ORCID: https://orcid.org/0000-0001-8768-9039, Prasai, A., Uleri, V. ORCID: https://orcid.org/0000-0001-5040-5995, Glatzova, D., Kraller, M., Cesnekova, M., Janusova, S., Salyova, E., Tsyklauri, O. ORCID: https://orcid.org/0000-0001-9997-5913, Kadlecek, T.A., Krizova, K., Platzer, R., Schober, K., Busch, D.H. ORCID: https://orcid.org/0000-0001-8713-093X, Weiss, A., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Stepanek, O. ORCID: https://orcid.org/0000-0002-2735-3311
Nature Immunology 24
(1): 174-185.
January 2023
A computational map of the human-SARS-CoV-2 protein-RNA interactome predicted at single-nucleotide resolution.
Horlacher, M. ORCID: https://orcid.org/0000-0002-7884-7135, Oleshko, S., Hu, Y. ORCID: https://orcid.org/0000-0003-3811-3206, Ghanbari, M. ORCID: https://orcid.org/0000-0002-6015-2968, Cantini, G. ORCID: https://orcid.org/0000-0003-1691-3560, Schinke, P. ORCID: https://orcid.org/0000-0002-0422-3215, Vergara, E.E., Bittner, F., Mueller, N.S, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Moyon, L. ORCID: https://orcid.org/0000-0003-2390-3942 and Marsico, A.
NAR Genomics and Bioinformatics 5
(1): lqad010.
March 2023
T-cell antigen recognition: catch-as-catch-can or catch-22?
Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Schütz, G.J.
EMBO Journal 42
(7): e113507.
3 April 2023
Mechanistic insights into T-Cell antigen recognition through single molecule microscopy.
Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Schütz, G.J.
In:
Encyclopedia of Cell Biology.
Encyclopedia of Cell Biology, 5
.
Elsevier, 536-552.
ISBN 978-0-12-821624-8
2023
Risk factors and characteristics influencing humoral response to COVID-19 vaccination in patients after allogeneic stem cell transplantation.
Hütter-Krönke, M.L., Neagoie, A., Blau, I.W., Wais, V., Vuong, L., Gantner, A., Ahn, J., Penack, O., Schnell, J., Nogai, K.A., Eberspächer, B., Saadati, M., Benner, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, H., Bunjes, D. and Sala, E.
Frontiers in Immunology 14
: 1174289.
3 May 2023
Monitoring mitochondrial translation by pulse SILAC.
Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Ishihama, Y. ORCID: https://orcid.org/0000-0001-7714-203X
Journal of Biological Chemistry 299
(2): 102865.
February 2023
Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors.
Immisch, L. ORCID: https://orcid.org/0000-0001-5072-8583, Papafotiou, G., Gallarín Delgado, N., Scheuplein, V., Paschen, A., Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X
Frontiers in Immunology 14
: 1119498.
16 February 2023
Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda et al.
Immisch, L. ORCID: https://orcid.org/0000-0001-5072-8583, Papafotiou, G., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X
Journal for ImmunoTherapy of Cancer 11
(3): e006784.
14 March 2023
Variable outcomes of hepatitis E infections in patients with hemato-oncologic diseases.
Ingwersen, V., Hofmann, J., Muche, M., Le Coutre, P., Schneider, T., Leng, C., Burmeister, T., Maschmeyer, G., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Schwartz, S.
Oncology Research and Treatment 46
(7-8): 296-302.
August 2023
Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.
Jahn, E. ORCID: https://orcid.org/0009-0001-0741-1166, Saadati, M., Fenaux, P., Gobbi, M., Roboz, G.J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Lutsik, P., Riedel, A., Plass, C. ORCID: https://orcid.org/0000-0003-2554-3952, Jahn, N., Walter, C., Holzmann, K., Hao, Y., Naim, S., Schreck, N., Krzykalla, J., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Keer, H.N., Azab, M., Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862 and Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536
Leukemia 37
(11): 2187-2196.
November 2023
Functional analysis of structural variants in single cells using Strand-seq.
Jeong, H. ORCID: https://orcid.org/0000-0002-1526-3343, Grimes, K. ORCID: https://orcid.org/0000-0002-4805-2366, Rauwolf, K.K., Bruch, P.M. ORCID: https://orcid.org/0000-0002-9992-3109, Rausch, T. ORCID: https://orcid.org/0000-0001-5773-5620, Hasenfeld, P. ORCID: https://orcid.org/0000-0003-2319-2482, Benito, E., Roider, T. ORCID: https://orcid.org/0000-0002-6973-3531, Sabarinathan, R., Porubsky, D. ORCID: https://orcid.org/0000-0001-8414-8966, Herbst, S.A. ORCID: https://orcid.org/0000-0001-8502-0366, Erarslan-Uysal, B., Jann, J.C. ORCID: https://orcid.org/0000-0003-2200-0151, Marschall, T. ORCID: https://orcid.org/0000-0002-9376-1030, Nowak, D. ORCID: https://orcid.org/0000-0001-7130-7921, Bourquin, J.P., Kulozik, A.E. ORCID: https://orcid.org/0000-0003-1953-0848, Dietrich, S., Bornhauser, B. ORCID: https://orcid.org/0000-0003-2890-3191, Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677 and Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794
Nature Biotechnology 41
(6): 832-844.
June 2023
Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses.
Jiang, B. ORCID: https://orcid.org/0000-0002-5862-5471, Schmitt, M.J. ORCID: https://orcid.org/0000-0001-8296-5858, Rand, U. ORCID: https://orcid.org/0000-0002-5946-4921, Company, C. ORCID: https://orcid.org/0000-0002-7975-0642, Dramaretska, Y. ORCID: https://orcid.org/0000-0002-9792-0465, Grossmann, M., Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658, Cicin-Sain, L. ORCID: https://orcid.org/0000-0003-3978-778X and Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251
Science Advances 9
(25): eadf4975.
23 June 2023
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level.
John, L. ORCID: https://orcid.org/0000-0001-8178-6890, Poos, A.M., Brobeil, A., Schinke, C. ORCID: https://orcid.org/0000-0002-2699-1741, Huhn, S., Prokoph, N., Lutz, R., Wagner, B., Zangari, M., Tirier, S.M., Mallm, J.P., Schumacher, S. ORCID: https://orcid.org/0000-0003-2292-9286, Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Solé-Boldo, L. ORCID: https://orcid.org/0000-0002-6974-9066, Quick, S., Steiger, S. ORCID: https://orcid.org/0000-0002-4845-5042, Przybilla, M.J., Bauer, K., Baumann, A., Hemmer, S., Rehnitz, C., Lückerath, C., Sachpekidis, C., Mechtersheimer, G., Haberkorn, U., Dimitrakopoulou-Strauss, A., Reichert, P., Barlogie, B., Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Goldschmidt, H. ORCID: https://orcid.org/0000-0003-0961-0035, Hillengass, J. ORCID: https://orcid.org/0000-0002-1778-0010, Rasche, L. ORCID: https://orcid.org/0000-0002-9536-9649, Haas, S.F. ORCID: https://orcid.org/0000-0001-9227-2051, van Rhee, F. ORCID: https://orcid.org/0000-0001-9959-1282, Rippe, K. ORCID: https://orcid.org/0000-0001-9951-9395, Raab, M.S. ORCID: https://orcid.org/0000-0003-4181-6922, Sauer, S. ORCID: https://orcid.org/0000-0002-5464-3234 and Weinhold, N.
Nature Communications 14
(1): 5011.
17 August 2023
DNA repair and antibody diversification: the 53BP1 paradigm.
Kabrani, E. ORCID: https://orcid.org/0000-0003-0834-9912, Saha, T. and Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793
Trends in Immunology 44
(10): 782-791.
October 2023
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx.
Karasaki, T. ORCID: https://orcid.org/0000-0001-6863-2360, Moore, D.A. ORCID: https://orcid.org/0000-0002-6296-1312, Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Magno, N., Ward, S. ORCID: https://orcid.org/0000-0002-6777-5279, Bakir, M.A. ORCID: https://orcid.org/0000-0002-0846-8332, Watkins, T.B.K., Grigoriadis, K. ORCID: https://orcid.org/0000-0002-8435-0176, Huebner, A. ORCID: https://orcid.org/0000-0001-8009-4999, Hill, M.S. ORCID: https://orcid.org/0000-0003-0718-8934, Frankell, A.M. ORCID: https://orcid.org/0000-0002-0341-7878, Abbosh, C. ORCID: https://orcid.org/0000-0002-8983-1382, Puttick, C., Zhai, H., Gimeno-Valiente, F., Saghafinia, S., Kanu, N., Dietzen, M. ORCID: https://orcid.org/0000-0002-6853-7563, Pich, O. ORCID: https://orcid.org/0000-0002-1956-1882, Lim, E.., Martínez-Ruiz, C. ORCID: https://orcid.org/0000-0002-4817-0565, Black, J.R.M., Biswas, D. ORCID: https://orcid.org/0000-0001-9141-5188, Campbell, B.B., Lee, C. ORCID: https://orcid.org/0000-0003-1715-2265, Colliver, E. ORCID: https://orcid.org/0000-0002-1497-0740, Enfield, K.S.S. ORCID: https://orcid.org/0000-0002-4551-6073, Hessey, S. ORCID: https://orcid.org/0000-0001-9856-424X, Hiley, C.T., Zaccaria, S. ORCID: https://orcid.org/0000-0002-5265-7392, Litchfield, K., Birkbak, N.J. ORCID: https://orcid.org/0000-0003-1613-9587, Cadieux, E.L., Demeulemeester, J. ORCID: https://orcid.org/0000-0002-2660-2478, Van Loo, P. ORCID: https://orcid.org/0000-0003-0292-1949, Adusumilli, P.S. ORCID: https://orcid.org/0000-0002-1699-2046, Tan, K.S., Cheema, W. ORCID: https://orcid.org/0000-0002-8000-7493, Sanchez-Vega, F. ORCID: https://orcid.org/0000-0002-2990-4893, Jones, D.R. ORCID: https://orcid.org/0000-0002-3318-0146, Rekhtman, N., Travis, W.D., Hackshaw, A. ORCID: https://orcid.org/0000-0002-5570-5070, Marafioti, T., Salgado, R. ORCID: https://orcid.org/0000-0002-1110-3801, Le Quesne, J. ORCID: https://orcid.org/0000-0003-3552-7446, Nicholson, A.G., McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018 and Jamal-Hanjani, M. ORCID: https://orcid.org/0000-0003-1212-1259
Nature Medicine 29
(4): 833-845.
April 2023
Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia.
Kayser, S., Martínez-Cuadrón, D., Rodriguez-Veiga, R., Hänel, M., Tormo, M., Schäfer-Eckart, K., Botella, C., Stölzel, F., Del Castillo, T.B., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Rodriguez-Medina, C., Held, G., Amigo, M.L., Schliemann, C., Colorado, M., Kaufmann, M., Garcia, M.B., Krause, S.W., Görner, M., Jost, E., Steffen, B., Zukunft, S., Platzbecker, U., Ho, A.D., Baldus, C.D., Serve, H., Müller-Tidow, C., Thiede, C., Bornhäuser, M., Montesinos, P., Röllig, C. and Schlenk, R.F.
Haematologica 108
(8): 2059-2066.
August 2023
Efficient determination of the accessible conformation space of multi-domain complexes based on EPR PELDOR data.
Kazemi, S., Lopata, A., Kniss, A., Pluska, L. ORCID: https://orcid.org/0000-0002-8669-6533, Güntert, P., Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202, Prisner, T.F., Collauto, A. and Dötsch, V.
Journal of Biomolecular NMR 77
(5-6): 261-269.
December 2023
IFNγ binding to extracellular matrix prevents fatal systemic toxicity.
Kemna, J. ORCID: https://orcid.org/0000-0002-2172-4441, Gout, E. ORCID: https://orcid.org/0000-0002-5424-6474, Daniau, L., Lao, J., Weißert, K. ORCID: https://orcid.org/0000-0002-9850-6039, Ammann, S. ORCID: https://orcid.org/0000-0003-0385-1890, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Richter, M. ORCID: https://orcid.org/0000-0002-5339-0781, Molenda, C. ORCID: https://orcid.org/0000-0003-0771-405X, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Zocholl, D. ORCID: https://orcid.org/0000-0002-9218-6919, Klopfleisch, R., Schütz, A. ORCID: https://orcid.org/0000-0002-0606-2574, Lortat-Jacob, H. ORCID: https://orcid.org/0000-0002-9772-0762, Aichele, P. ORCID: https://orcid.org/0000-0002-0891-9877, Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141 and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Nature Immunology 24
(3): 414-422.
March 2023
Osteopontin is a prognostic circulating biomarker in patients with neuroendocrine neoplasms.
Kidess, E., Giesecke, Y., Eichhorn, I., Mohr, R., Jann, H., Fischer, C., Wiedenmann, B., Roderburg, C., Tacke, F. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Journal of Cancer Research and Clinical Oncology 149
(12): 10925-10933.
September 2023
AML with complex karyotype: extreme genomic complexity revealed by combined long-read sequencing and Hi-C technology.
Klever, M.K., Sträng, E., Hetzel, S., Jungnitsch, J., Dolnik, A., Schöpflin, R., Schrezenmeier, J.F.F., Schick, F., Blau, O., Westermann, J., Rücker, F.G., Xia, Z., Döhner, K., Schrezenmeier, H., Spielmann, M., Meissner, A., Melo, U.S., Mundlos, S. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood Advances 7
(21): 6520-6531.
14 November 2023
Identification of drug candidates targeting monocyte reprogramming in people living with HIV.
Knoll, R., Bonaguro, L., Dos Santos, J.C., Warnat-Herresthal, S., Jacobs-Cleophas, M.C.P., Blümel, E., Reusch, N., Horne, A. ORCID: https://orcid.org/0000-0002-4209-4573, Herbert, M., Nuesch-Germano, M., Otten, T., van der Heijden, W.A., van de Wijer, L., Shalek, A.K., Händler, K., Becker, M., Beyer, M.D., Netea, M.G., Joosten, L.A.B., van der Ven, A.J.A.M., Schultze, J.L. and Aschenbrenner, A.C.
Frontiers in Immunology 14
: 1275136.
20 November 2023
Resolving crosstalk between signaling pathways using mathematical modeling and time-resolved single cell data.
Konrath, F. ORCID: https://orcid.org/0000-0002-6843-6252, Loewer, A. ORCID: https://orcid.org/0000-0002-8819-3040 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
Methods in Molecular Biology 2634
: 267-284.
2023
A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1.
Konrath, F. ORCID: https://orcid.org/0000-0002-6843-6252, Willenbrock, M., Busse, D., Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
iScience 26
(10): 107917.
20 October 2023
The DNA methylation status of the TERT promoter differs between subtypes of mature B-cell lymphomas.
Kouroukli, A.G., Fischer, A. ORCID: https://orcid.org/0000-0002-7145-2544, Kretzmer, H., Chteinberg, E., Rajaram, N., Glaser, S., Kolarova, J., Bashtrykov, P., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Drexler, H.G., Ohno, H., Ammerpohl, O., Jeltsch, A. ORCID: https://orcid.org/0000-0001-6113-9290, Siebert, R. and Bens, S. ORCID: https://orcid.org/0009-0008-5263-495X
Blood Cancer Journal 13
(1): 98.
26 June 2023
Synchrones Auftreten eines Adenokarzinoms und eines Non-Hodgkin B-Zell-Lymphoms bei einem Patienten mit einem variablen Immundefektsyndrom (CVID) [When malignancy hits twice - synchronous gastric carcinoma and non-Hodgkin-B-cell lymphoma in a patient with common variable immunodeficiency].
Krick, D., Hauptmann, K., Penndorf, V., Tacke, F., Krüger, R., von Bernuth, H. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Zeitschrift fur Gastroenterologie 61
(7): 827-831.
July 2023
Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis.
Kurtova, A.V., Heinlein, M., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Velten, L., Dijkgraaf, G.J.P., Storm, E.E., Kljavin, N.M., Boumahdi, S., Himmels, P., Herault, A., Mancini, A.G., Koeppen, H., Dail, M., Yan, M., Zhang, J., Koch, U., Radtke, F., Modrusan, Z., Metcalfe, C., Piskol, R. and de Sauvage, F.J.
Blood Advances 7
(4): 491-507.
28 February 2023
Mechanisms of resistance to small molecules in acute myeloid leukemia.
Lang, T.J.L., Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Frick, M. ORCID: https://orcid.org/0000-0001-5216-0565
Cancers 15
(18): 4573.
15 September 2023
Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.
Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Dubois, S.M. ORCID: https://orcid.org/0000-0002-3169-2893, Buquicchio, F.A., Hsieh, Y.H. ORCID: https://orcid.org/0000-0003-3037-8728, Garg, K., Kautz, P. ORCID: https://orcid.org/0000-0002-9658-1676, Nitsch, L. ORCID: https://orcid.org/0000-0003-0775-1969, Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271, Maschmeyer, P. ORCID: https://orcid.org/0000-0002-1705-5302, Verboon, J.M., Gutierrez, J.C., Yin, Y. ORCID: https://orcid.org/0000-0002-2220-005X, Fiskin, E., Luo, W., Mimitou, E.P. ORCID: https://orcid.org/0000-0001-9737-6394, Muus, C., Malhotra, R., Parikh, S., Fleming, M.D. ORCID: https://orcid.org/0000-0003-0948-4024, Oevermann, L., Schulte, J. ORCID: https://orcid.org/0000-0003-0671-1201, Eckert, C., Kundaje, A. ORCID: https://orcid.org/0000-0003-3084-2287, Smibert, P. ORCID: https://orcid.org/0000-0003-0772-1647, Vardhana, S.A. ORCID: https://orcid.org/0000-0002-3100-1298, Satpathy, A.T. ORCID: https://orcid.org/0000-0002-5167-537X, Regev, A. ORCID: https://orcid.org/0000-0003-3293-3158, Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X, Agarwal, S. ORCID: https://orcid.org/0000-0003-4910-3118 and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
Nature Genetics 55
(7): 1198-1209.
July 2023
Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility.
Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Liu, V. ORCID: https://orcid.org/0000-0002-6790-6603, Muus, C., Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271, Nitsch, L. ORCID: https://orcid.org/0000-0003-0775-1969, Kautz, P. ORCID: https://orcid.org/0000-0002-9658-1676, Sandor, K. ORCID: https://orcid.org/0000-0003-2892-4865, Yin, Y. ORCID: https://orcid.org/0000-0002-2220-005X, Gutierrez, J.C., Pelka, K. ORCID: https://orcid.org/0000-0003-2856-8602, Satpathy, A.T. ORCID: https://orcid.org/0000-0002-5167-537X, Regev, A., Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
Nature Protocols 18
(5): 1416-1440.
May 2023
Latent human herpesvirus 6 is reactivated in CAR T cells.
Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Yin, Y. ORCID: https://orcid.org/0000-0002-2220-005X, Maurer, K. ORCID: https://orcid.org/0000-0002-4160-181X, Sandor, K.D. ORCID: https://orcid.org/0000-0003-2892-4865, Daniel, B. ORCID: https://orcid.org/0000-0002-2410-8767, Yagnik, G., Peña, J. ORCID: https://orcid.org/0000-0002-9662-906X, Crawford, J.C. ORCID: https://orcid.org/0000-0003-4096-6048, Spanjaart, A.M. ORCID: https://orcid.org/0000-0003-0167-6021, Gutierrez, J.C., Haradhvala, N.J. ORCID: https://orcid.org/0000-0003-1113-3135, Riberdy, J.M., Abay, T. ORCID: https://orcid.org/0009-0009-0024-2732, Stickels, R.R. ORCID: https://orcid.org/0000-0003-4326-4084, Verboon, J.M., Liu, V. ORCID: https://orcid.org/0000-0002-6790-6603, Buquicchio, F.A., Wang, F. ORCID: https://orcid.org/0009-0000-8310-3088, Southard, J., Song, R., Li, W., Shrestha, A., Parida, L. ORCID: https://orcid.org/0000-0002-7872-5074, Getz, G. ORCID: https://orcid.org/0000-0002-0936-0753, Maus, M.V. ORCID: https://orcid.org/0000-0002-7578-0393, Li, S. ORCID: https://orcid.org/0000-0001-9106-6141, Moore, A., Roberts, Z.J., Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Talleur, A.C. ORCID: https://orcid.org/0000-0002-6558-6706, Thomas, P.G. ORCID: https://orcid.org/0000-0001-7955-0256, Dehghani, H., Pertel, T., Kundaje, A. ORCID: https://orcid.org/0000-0003-3084-2287, Gottschalk, S. ORCID: https://orcid.org/0000-0003-3991-7468, Roth, T.L. ORCID: https://orcid.org/0000-0002-3970-9573, Kersten, M.J. ORCID: https://orcid.org/0000-0002-8904-3802, Wu, C.J. ORCID: https://orcid.org/0000-0002-3348-5054, Majzner, R.G. ORCID: https://orcid.org/0000-0001-6969-8011 and Satpathy, A.T. ORCID: https://orcid.org/0000-0002-5167-537X
Nature 623
: 608-615.
16 November 2023
Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B cell impairment and increases the risk for infections - a retrospective matched cohort study.
Launspach, M., Temel, D., Ohlendorf, E., Zirngibl, F., Materne, B., Oevermann, L., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Künkele, A., Hundsdörfer, P., von Bernuth, H., Pruß, A., Eggert, A., von Stackelberg, A., Lang, P. and Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201
Haematologica 108
(1): 267-272.
January 2023
Discriminating promiscuous from target-specific autoantibodies in COVID-19.
Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195, Vazquez Garcia, C. ORCID: https://orcid.org/0000-0003-4583-7616, Spatt, L., Ratswohl, C. ORCID: https://orcid.org/0000-0001-5413-0730, Thibeault, C., Ostendorf, L. ORCID: https://orcid.org/0000-0003-3553-6406, Alexander, T. ORCID: https://orcid.org/0000-0003-1193-0097, Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Sander, L.E., Kurth, F. and de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157
European Journal of Immunology 53
(5): e2250210.
May 2023
Pan-conserved segment tags identify ultra-conserved sequences across assemblies in the human pangenome.
Lee, H., Greer, S.U., Pavlichin, D.S., Zhou, B., Urban, A.E., Weissman, T. and Ji, H.P.
Cell Reports Methods 3
(8): 100543.
28 August 2023
Clinical and prognostic relevance of cardiac wasting in patients with advanced cancer.
Lena, A., Wilkenshoff, U., Hadzibegovic, S., Porthun, J., Rösnick, L., Fröhlich, A.K., Zeller, T., Karakas, M., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Ahn, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Riess, H., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Totzeck, M., Rassaf, T., Burkhoff, D., Mehra, M.R., Bax, J.J., Butler, J., Edelmann, F., Haverkamp, W., Anker, S.D., Packer, M., Coats, A.J.S., von Haehling, S., Landmesser, U. and Anker, M.S.
Journal of the American College of Cardiology 81
(16): 1569-1586.
25 April 2023
Hepatobiliary long-term consequences of COVID-19: dramatically increased rate of secondary sclerosing cholangitis in critically ill COVID-19 patients.
Leonhardt, S., Jürgensen, C., Frohme, J., Grajecki, D., Adler, A., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Leonhardt, J., Voll, J.M., Kruse, J.M., Körner, R., Eckardt, K.U., Janssen, H.J., Gebhardt, V., Schmittner, M.D., Frey, C., Müller-Ide, H., Bauer, M., Thibeault, C., Kurth, F., Sander, L.E., Müller, T. and Tacke, F.
Hepatology International 17
(6): 1610-1625.
December 2023
A weak-labelling and deep learning approach for in-focus object segmentation in 3D widefield microscopy.
Li, R. ORCID: https://orcid.org/0000-0002-3085-5267, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Yakimovich, A.
Scientific Reports 13
(1): 12275.
28 July 2023
A draft human pangenome reference.
Liao, W.W., Asri, M., Ebler, J., Doerr, D., Haukness, M., Hickey, G., Lu, S., Lucas, J.K., Monlong, J., Abel, H.J., Buonaiuto, S., Chang, X.H., Cheng, H., Chu, J., Colonna, V., Eizenga, J.M., Feng, X., Fischer, C., Fulton, R.S., Garg, S., Groza, C., Guarracino, A., Harvey, W.T., Heumos, S., Howe, K., Jain, M., Lu, T.Y., Markello, C., Martin, F.J., Mitchell, M.W., Munson, K.M., Mwaniki, M.N., Novak, A.M., Olsen, H.E., Pesout, T., Porubsky, D., Prins, P., Sibbesen, J.A., Sirén, J., Tomlinson, C., Villani, F., Vollger, M.R., Antonacci-Fulton, L.L., Baid, G., Baker, C.A., Belyaeva, A., Billis, K., Carroll, A., Chang, P.C., Cody, S., Cook, D.E., Cook-Deegan, R.M., Cornejo, O.E., Diekhans, M., Ebert, P., Fairley, S., Fedrigo, O., Felsenfeld, A.L., Formenti, G., Frankish, A., Gao, Yan, Garrison, N.A., Giron, C.G., Green, R.E., Haggerty, L., Hoekzema, K., Hourlier, T., Ji, H.P., Kenny, E.E., Koenig, B.A., Kolesnikov, A., Korbel, J.O., Kordosky, J., Koren, S., Lee, H.J., Lewis, A.P., Magalhães, H., Marco-Sola, S., Marijon, P., McCartney, A., McDaniel, J., Mountcastle, J., Nattestad, M., Nurk, S., Olson, N.D., Popejoy, A.B., Puiu, D., Rautiainen, M., Regier, A.A., Rhie, A., Sacco, S., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Schneider, V.A., Schultz, B.I., Shafin, K., Smith, M.W., Sofia, H.J., Abou Tayoun, A.N., Thibaud-Nissen, F., Tricomi, F.F., Wagner, J., Walenz, B., Wood, J.M.D., Zimin, A.V., Bourque, G., Chaisson, M.J P, Flicek, Paul, Phillippy, A.M., Zook, J.M., Eichler, E.E., Haussler, D., Wang, T., Jarvis, E.D., Miga, K.H., Garrison, E., Marschall, T., Hall, I.M., Li, H. and Paten, B.
Nature 617
(7960): 312-324.
11 May 2023
Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Beccaceci, G. ORCID: https://orcid.org/0000-0002-6453-3725, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Li, H. ORCID: https://orcid.org/0000-0001-5677-3377, Liu, L. ORCID: https://orcid.org/0000-0002-9553-5475, Müllerke, S., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Heymann, F., Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 14
(1): 3025.
25 May 2023
Human embryo models: unveiling sophisticated self-organization of stem cells during post-implantation stages.
Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Signal Transduction and Targeted Therapy 8
(1): 419.
6 November 2023
Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia.
Ling, V.Y. ORCID: https://orcid.org/0000-0001-9757-1229, Straube, J. ORCID: https://orcid.org/0000-0002-1748-0659, Godfrey, W., Haldar, R., Janardhanan, Y., Cooper, L., Bruedigam, C., Cooper, E., Tavakoli Shirazi, P., Jacquelin, S. ORCID: https://orcid.org/0000-0001-5087-3641, Tey, S.K. ORCID: https://orcid.org/0000-0001-9567-382X, Baell, J., Huang, F. ORCID: https://orcid.org/0000-0002-5290-2490, Jin, J., Zhao, Y., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Bywater, M.J. and Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209
Leukemia 37
(1): 143-153.
January 2023
SLAM-Drop-seq reveals mRNA kinetic rates throughout the cell cycle.
Liu, H. ORCID: https://orcid.org/0009-0007-4871-452X, Arsiè, R. ORCID: https://orcid.org/0000-0002-7869-7624, Schwabe, D. ORCID: https://orcid.org/0000-0003-2825-3352, Schilling, M. ORCID: https://orcid.org/0000-0002-3453-7792, Minia, I. ORCID: https://orcid.org/0000-0003-1012-3373, Alles, J. ORCID: https://orcid.org/0000-0003-0681-0410, Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Falcke, M. ORCID: https://orcid.org/0000-0001-7137-1114, Friedman, N. ORCID: https://orcid.org/0000-0002-9678-3550, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Molecular Systems Biology 19
(10): e11427.
12 October 2023
Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.
Lluch, A. ORCID: https://orcid.org/0000-0003-4216-4436, Latorre, J., Serena-Maione, A. ORCID: https://orcid.org/0000-0003-1460-7033, Espadas, I. ORCID: https://orcid.org/0000-0002-9811-9717, Caballano-Infantes, E. ORCID: https://orcid.org/0000-0001-8269-9158, Moreno-Navarrete, J.M. ORCID: https://orcid.org/0000-0002-2883-511X, Oliveras-Cañellas, N. ORCID: https://orcid.org/0000-0002-7758-3326, Ricart, W., Malagón, M.M. ORCID: https://orcid.org/0000-0002-2419-2727, Martin-Montalvo, A. ORCID: https://orcid.org/0000-0002-3886-5355, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Szymanski, W. ORCID: https://orcid.org/0000-0002-1202-3299, Graumann, J. ORCID: https://orcid.org/0000-0002-3015-5850, Gómez-Serrano, M. ORCID: https://orcid.org/0000-0002-9669-091X, Sommariva, E. ORCID: https://orcid.org/0000-0003-2172-4051, Fernández-Real, J.M. ORCID: https://orcid.org/0000-0002-7442-9323 and Ortega, F.J. ORCID: https://orcid.org/0000-0003-2111-769X
Nature Communications 14
(1): 5106.
22 August 2023
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
Lo, W.T., Belabed, H., Kücükdisli, M., Metag, J., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Prokofeva, P., Ohashi, Y. ORCID: https://orcid.org/0000-0002-2288-130X, Horatscheck, A. ORCID: https://orcid.org/0000-0001-6485-6391, Cirillo, D. ORCID: https://orcid.org/0000-0001-5133-0702, Krauss, M., Schmied, C. ORCID: https://orcid.org/0000-0003-2058-1124, Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Médard, G. ORCID: https://orcid.org/0000-0002-4782-4029, Kuster, Be. ORCID: https://orcid.org/0000-0002-9094-1677, Perisic, O., Williams, R.L. ORCID: https://orcid.org/0000-0001-7754-4207, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Payrastre, B. ORCID: https://orcid.org/0000-0002-8693-0190, Severin, S., Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330 and Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993
Nature Chemical Biology 19
(1): 18-27.
January 2023
Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas.
Lopez, C., Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Bernhart, S.H., Kleinheinz, K., Sungalee, S., Sczakiel, H.L. ORCID: https://orcid.org/0000-0003-3836-163X, Kretzmer, H., Toprak, U.H., Glaser, S., Wagener, R., Ammerpohl, O., Bens, S., Giefing, M., Sanchez, J.C.G., Apic, G., Hubschmann, D., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Kreuz, M., Mottok, A., Müller, J.M., Seufert, J., Hoffmann, S., Korbel, J.O., Russell, R.B., Schule, R., Trumper, L., Klapper, W., Radlwimmer, B., Lichter, P., Kuppers, R., Schlesner, M., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413 and Siebert, R.
Haematologica 108
(2): 543-554.
1 February 2023
Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
Lowenstein, E.D. ORCID: https://orcid.org/0000-0003-3755-0818, Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Misios, A., Osman, K.L., Li, H., Greenberg, R.S., Thompson, R., Song, K. ORCID: https://orcid.org/0000-0001-6216-8157, Dietrich, S. ORCID: https://orcid.org/0000-0002-0753-9266, Li, X. ORCID: https://orcid.org/0000-0002-1173-1066, Vladimirov, N. ORCID: https://orcid.org/0000-0002-1159-0689, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Brunet, J.F., Zampieri, N. ORCID: https://orcid.org/0000-0002-2228-9453, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Liberles, S.D., Jia, S., Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Lever, T.E. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Neuron 111
(14): 2184-2200.e7.
19 July 2023
Concomitant sequencing of accessible chromatin and mitochondrial genomes in single cells using mtscATAC-seq.
Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164 and Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807
Methods in Molecular Biology 2611
: 269-282.
2023
A comprehensive molecular profiling approach reveals metabolic alterations that steer bone tissue regeneration.
Löffler, J., Noom, A., Ellinghaus, A., Dienelt, A., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Duda, G.N. ORCID: https://orcid.org/0000-0001-7605-3908
Communications Biology 6
(1): 327.
27 March 2023
Rat cytomegalovirus efficiently replicates in dendritic cells and induces changes in their transcriptional profile.
Madela-Mönchinger, J.C., Wolf, S.A., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Bauer, A., Mischke, M., Möller, L., Juranić Lisnić, V., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Malyshkina, A. and Voigt, S. ORCID: https://orcid.org/0000-0003-1544-9903
Frontiers in Immunology 14
: 1192057.
23 November 2023
A framework for ultra-low-input spatial tissue proteomics.
Makhmut, A. ORCID: https://orcid.org/0009-0009-6913-4289, Qin, D. ORCID: https://orcid.org/0000-0002-9730-4072, Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, König, J. and Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081
Cell Systems 14
(11): 1002-1014.
15 November 2023
RIF1 regulates early replication timing in murine B cells.
Malzl, D., Peycheva, M. ORCID: https://orcid.org/0000-0001-9268-0637, Rahjouei, A. ORCID: https://orcid.org/0000-0003-3973-6333, Gnan, S. ORCID: https://orcid.org/0000-0003-3314-4302, Klein, K.N., Nazarova, M. ORCID: https://orcid.org/0000-0001-5293-4161, Schoeberl, U.E. ORCID: https://orcid.org/0000-0002-6105-5385, Gilbert, D.M. ORCID: https://orcid.org/0000-0001-8087-9737, Buonomo, S.C.B. ORCID: https://orcid.org/0000-0002-0177-2884, Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793, Neumann, T. ORCID: https://orcid.org/0000-0003-3908-4224 and Pavri, R. ORCID: https://orcid.org/0000-0002-6191-6333
Nature Communications 14
(1): 8049.
11 December 2023
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.
Mansouri, L., Thorvaldsdottir, B., Sutton, L.A., Karakatsoulis, G., Meggendorfer, M., Parker, H., Nadeu, F., Brieghel, C., Laidou, S., Moia, R., Rossi, D., Catherwood, M., Kotaskova, J., Delgado, J., Rodríguez-Vicente, A.E., Benito, R., Rigolin, G.M., Bonfiglio, S., Scarfo, L., Mattsson, M., Davis, Z., Gogia, A., Rani, L., Baliakas, P., Foroughi-Asl, H., Jylhä, C., Skaftason, A., Rapado, I., Miras, F., Martinez-Lopez, J., de la Serna, J., Rivas, J.M.H., Thornton, P., Larráyoz, M.J., Calasanz, M.J., Fésüs, V., Mátrai, Z., Bödör, C., Smedby, K.E., Espinet, B., Puiggros, A., Gupta, R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Bosch, F., Tazón-Vega, B., Baran-Marszak, F., Oscier, D., Nguyen-Khac, F., Zenz, T., Terol, M.J., Cuneo, A., Hernández-Sánchez, M., Pospisilova, S., Mills, K., Gaidano, G., Niemann, C.U., Campo, E., Strefford, J.C., Ghia, P., Stamatopoulos, K. and Rosenquist, R.
Leukemia 37
(2): 339-347.
February 2023
The little skate genome and the evolutionary emergence of wing-like fins.
Marlétaz, F. ORCID: https://orcid.org/0000-0001-8124-4266, de la Calle-Mustienes, E., Acemel, R.D. ORCID: https://orcid.org/0000-0003-4120-0140, Paliou, C., Naranjo, S. ORCID: https://orcid.org/0000-0002-4529-3332, Martínez-García, P.M. ORCID: https://orcid.org/0000-0002-2119-2465, Cases, I. ORCID: https://orcid.org/0000-0002-8784-5174, Sleight, V.A., Hirschberger, C., Marcet-Houben, M., Navon, D., Andrescavage, A., Skvortsova, K., Duckett, P.Ed., González-Rajal, Á., Bogdanovic, O. ORCID: https://orcid.org/0000-0001-5680-0056, Gibcus, J.H. ORCID: https://orcid.org/0000-0002-0851-7560, Yang, L., Gallardo-Fuentes, L., Sospedra, I., Lopez-Rios, J., Darbellay, F. ORCID: https://orcid.org/0000-0001-6942-3325, Visel, A. ORCID: https://orcid.org/0000-0002-4130-7784, Dekker, J. ORCID: https://orcid.org/0000-0001-5631-0698, Shubin, N., Gabaldón, T. ORCID: https://orcid.org/0000-0003-0019-1735, Nakamura, T. ORCID: https://orcid.org/0000-0003-0183-1685, Tena, J.J. ORCID: https://orcid.org/0000-0001-8165-7984, Lupianez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X, Rokhsar, D.S. ORCID: https://orcid.org/0000-0002-8704-2224 and Gómez-Skarmeta, J.L.
Nature 616
(7957): 495-503.
20 April 2023
Influence of corticosteroid treatment on CXCR4 expression in DLBCL.
Martin, S., Viertl, D., Janz, A., Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Schottelius, M. ORCID: https://orcid.org/0000-0002-1928-6913
EJNMMI Research 13
(1): 40.
10 May 2023
Genomic–transcriptomic evolution in lung cancer and metastasis.
Martínez-Ruiz, C., Black, J.R.M., Puttick, C., Hill, M.S., Demeulemeester, J., Larose Cadieux, E., Thol, K., Jones, T.P., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Prymas, P., Rowan, A., Ward, S., Cubitt, L., Athanasopoulou, F., Pich, O., Karasaki, T., Moore, D.A., Salgado, R., Colliver, E., Castignani, C., Dietzen, M., Huebner, A., Al Bakir, M., Tanić, M., Watkins, T.B.K., Lim, E.L., Al-Rashed, A.M., Lang, D., Clements, J., Cook, D.E., Rosenthal, R., Wilson, G. A., Frankell, A.M., de Carné Trécesson, S., East, P., Kanu, N., Litchfield, K., Birkbak, N.J., Hackshaw, A., Beck, S., Van Loo, P., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
(7957): 543-552.
20 April 2023
Optimising urinary catecholamine metabolite diagnostics for neuroblastoma.
Matser, Y.A.H. ORCID: https://orcid.org/0000-0002-7182-3202, Verly, I.R.N. ORCID: https://orcid.org/0000-0001-6745-3360, van der Ham, M., de Sain‐van der Velden, M.G.M., Verhoeven‐Duif, N.M., Ash, S., Cangemi, G., Barco, S., Popovic, M.B., van Kuilenburg, A.B.P. and Tytgat, G.A.M. ORCID: https://orcid.org/0000-0003-4452-0748
Pediatric Blood and Cancer 70
(6): e30289.
June 2023
Human induced pluripotent stem cell-derived pericytes as scalable and editable source to study direct lineage reprogramming into induced neurons.
Menon, R., Petrucci, L., Lohrer, B., Zhang, J., Schulze, M., Schichor, C., Winner, B., Winkler, J., Riemenschneider, M.J., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Falk, S. and Karow, M. ORCID: https://orcid.org/0000-0003-4935-1365
Cellular Reprogramming 25
(5): 212-223.
13 October 2023
Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence.
Miller, D.C. ORCID: https://orcid.org/0000-0001-9852-677X, Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072, Genehr, C., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Priller, J. ORCID: https://orcid.org/0000-0001-7596-0979, Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952 and Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992
Stem Cell Research 68
: 103056.
April 2023
CRISPR/Cas9 screen in gastric cancer patient-derived organoids reveals KDM1A-NDRG1 axis as a targetable vulnerability.
Mircetic, J. ORCID: https://orcid.org/0000-0002-9481-240X, Camgöz, A., Abohawya, M., Ding, L., Dietzel, J., Tobar, S.G., Paszkowski-Rogacz, M., Seidlitz, T., Schmäche, T., Mehnert, M.C., Sidorova, O. ORCID: https://orcid.org/0009-0004-1459-1662, Weitz, J., Buchholz, F. ORCID: https://orcid.org/0000-0002-4577-3344 and Stange, D.E.
Small Methods 7
(6): e2201605.
20 June 2023
Toward identification of functional sequences and variants in noncoding DNA.
Monti, R. ORCID: https://orcid.org/0000-0002-6354-8319 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Annual Review of Biomedical Data Science 6
: 191-210.
August 2023
CLK2 and CLK4 are regulators of DNA damage-induced NF-κB targeted by novel small molecule inhibitors.
Mucka, P. ORCID: https://orcid.org/0000-0003-2125-0634, Lindemann, P. ORCID: https://orcid.org/0000-0002-8224-3764, Bosco, B. ORCID: https://orcid.org/0000-0002-3069-714X, Willenbrock, M., Radetzki, S. ORCID: https://orcid.org/0000-0003-2688-2868, Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, Brischetto, C. ORCID: https://orcid.org/0000-0001-9167-3291, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
Cell Chemical Biology 30
(10): 1303-1312.e3.
19 October 2023
Adjustments to the reference dataset design improve cell type label transfer.
Mölbert, C. ORCID: https://orcid.org/0000-0003-3580-4968 and Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170
Frontiers in Bioinformatics 3
: 1150099.
5 April 2023
Editorial: Modulation of human immune parameters by anticancer therapies, volume II.
Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Sack, U. and Sánchez-Ramón, S.
Frontiers in Immunology 14
: 1249099.
26 July 2023
Linoleic acid potentiates CD8(+) T cell metabolic fitness and antitumor immunity.
Nava Lauson, C.B., Tiberti, S., Corsetto, P.A., Conte, F., Tyagi, P., Machwirth, M., Ebert, S., Loffreda, A., Scheller, L., Sheta, D., Mokhtari, Z., Peters, T., Raman, A.T., Greco, F., Rizzo, A.M., Beilhack, A., Signore, G., Tumino, N., Vacca, P., McDonnell, L.A., Raimondi, A., Greenberg, P.D., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Cardaci, S., Caruana, I., Rodighiero, S., Nezi, L. and Manzo, T.
Cell Metabolism 35
(4): 633-650.e9.
4 April 2023
A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Bakina, O. ORCID: https://orcid.org/0000-0002-3486-9906, Badillo Lisakowski, V. ORCID: https://orcid.org/0000-0001-5906-2589, Olivares-Chauvet, P., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172, Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Molecular Systems Biology 19
(2): e11147.
10 February 2023
C/EBPβ-induced lymphoid-to-myeloid transdifferentiation emulates granulocyte-monocyte progenitor biology.
Nguyen, L.T., Zimmermann, K., Kowenz-Leutz, E., Lim, R., Hofstätter, M. ORCID: https://orcid.org/0000-0002-6198-2859, Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427 and Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X
Stem Cell Reports 19
(1): 112-125.
28 December 2023
Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root.
Nolan, T.M. ORCID: https://orcid.org/0000-0003-1362-2557, Vukašinović, N. ORCID: https://orcid.org/0000-0003-2740-7874, Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Zhang, J., Vanhoutte, I. ORCID: https://orcid.org/0000-0003-2878-134X, Shahan, R. ORCID: https://orcid.org/0000-0001-7702-9432, Taylor, I.W. ORCID: https://orcid.org/0000-0002-6535-8658, Greenstreet, L. ORCID: https://orcid.org/0000-0003-0635-3870, Heitz, M. ORCID: https://orcid.org/0000-0003-1552-1688, Afanassiev, A., Wang, P. ORCID: https://orcid.org/0000-0002-4484-6329, Szekely, P. ORCID: https://orcid.org/0000-0002-1569-4151, Brosnan, A. ORCID: https://orcid.org/0000-0002-9979-4060, Yin, Y. ORCID: https://orcid.org/0000-0002-3044-9701, Schiebinger, G., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Russinova, E. ORCID: https://orcid.org/0000-0002-0569-1977 and Benfey, P.N. ORCID: https://orcid.org/0000-0001-5302-758X
Science 379
(6639): eadf4721.
31 March 2023
Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters.
Nouailles, G. ORCID: https://orcid.org/0000-0003-1973-3119, Adler, J.M. ORCID: https://orcid.org/0000-0001-8147-0351, Pennitz, P. ORCID: https://orcid.org/0000-0002-8132-7237, Peidli, S. ORCID: https://orcid.org/0000-0002-4257-8690, Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Baumgardt, M. ORCID: https://orcid.org/0000-0003-2077-3716, Bushe, J., Voss, A., Langenhagen, A., Langner, C. ORCID: https://orcid.org/0000-0001-7311-3477, Martin Vidal, R. ORCID: https://orcid.org/0000-0002-9670-5640, Pott, F. ORCID: https://orcid.org/0000-0003-3700-1691, Kazmierski, J. ORCID: https://orcid.org/0000-0002-7962-2165, Ebenig, A. ORCID: https://orcid.org/0000-0001-7066-0184, Lange, M.V., Mühlebach, M.D. ORCID: https://orcid.org/0000-0002-7069-5018, Goekeri, C. ORCID: https://orcid.org/0000-0002-1616-4005, Simmons, S., Xing, N., Abdelgawad, A., Herwig, S., Cichon, G., Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Drosten, C. ORCID: https://orcid.org/0000-0001-7923-0519, Goffinet, C. ORCID: https://orcid.org/0000-0002-3959-004X, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Wu, H., Witzenrath, M., Gruber, A.D. ORCID: https://orcid.org/0000-0002-4502-0393, Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271, Osterrieder, N., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Kunec, D. ORCID: https://orcid.org/0000-0001-6697-7621 and Trimpert, J. ORCID: https://orcid.org/0000-0003-1616-0810
Nature Microbiology 8
(5): 860-874.
May 2023
Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.
Nurminen, A., Jaatinen, S., Taavitsainen, S., Högnäs, G., Lesluyes, T., Ansari-Pour, N., Tolonen, T., Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Koskenalho, A., Kankainen, M., Jasu, J., Rauhala, H., Kesäniemi, J., Nikupaavola, T., Kujala, P., Rinta-Kiikka, I., Riikonen, J., Kaipia, A., Murtola, T., Tammela, T.L., Visakorpi, T., Nykter, M., Wedge, D.C., Van Loo, P. and Bova, G.S. ORCID: https://orcid.org/0000-0003-1639-3104
Genome Medicine 15
(1): 82.
12 October 2023
Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation.
Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Keilholz, L., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Frentsch, M., Blau, I.W., Vuong, L., Lesch, S., Movasshagi, K., Tietze-Stolley, C., Loyal, L., Henze, L., Penack, O., Stervbo, U. ORCID: https://orcid.org/0000-0002-2831-8868, Babel, N., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wittenbecher, F. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 14
: 1114368.
10 February 2023
Clinical implications and dynamics of clonal hematopoiesis in anti-CD19 CAR T-cell treated patients.
Panagiota, V., Kerschbaum, J.F., Penack, O., Stein, C.M., Arends, C.M., Koenecke, C., Strzelecka, P.M. ORCID: https://orcid.org/0000-0003-0226-6788, Kloos, A., Wiegand, L., Lasch, A., Altwasser, R. ORCID: https://orcid.org/0009-0002-6216-6068, Halik, A., Gabdoulline, R., Thomson, J., Weibl, K., Franke, G.N., Berger, C., Hasenkamp, J., Ayuk, F., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Beutel, G., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wulf, G.G., Kröger, N., Vucinic, V., Heuser, M. and Damm, F.
HemaSphere 7
(10): e957.
October 2023
MDC1 maintains active elongation complexes of RNA polymerase II.
Pappas, G., Munk, S.H.N., Watanabe, K., Thomas, Q., Gál, Z., Gram, H.H., Lee, M.H., Gómez-Cabello, D., Kanellis, D.C., Olivares-Chauvet, P., Larsen, D.H., Gregersen, L.H. ORCID: https://orcid.org/0000-0002-1205-604X, Maya-Mendoza, A., Galanos, P. and Bartek, J.
Cell Reports 42
(1): 111979.
31 January 2023
Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
Pearson, A.D.J., Federico, S. ORCID: https://orcid.org/0000-0002-5807-4876, Gatz, S.A., Ortiz, M., Lesa, G., Scobie, N. ORCID: https://orcid.org/0000-0002-6539-2741, Gounaris, I. ORCID: https://orcid.org/0000-0003-2755-6597, Weiner, S.L., Weigel, B., Unger, T.J., Stewart, E., Smith, M., Slotkin, E.K., Reaman, G., Pappo, A. ORCID: https://orcid.org/0000-0002-5338-3979, Nysom, K. ORCID: https://orcid.org/0000-0003-2935-0058, Norga, K., McDonough, J., Marshall, L.V., Ludwinski, D. ORCID: https://orcid.org/0000-0003-4717-7690, Ligas, F., Karres, D., Kool, M., Horner, T.J., Henssen, A. ORCID: https://orcid.org/0000-0003-1534-778X, Heenen, D. ORCID: https://orcid.org/0000-0002-7703-9902, Hawkins, D.S., Gore, L., Bender, J.G., Galluzzo, S., Fox, E., de Rojas, T., Davies, B.R., Chakrabarti, J., Carmichael, J., Bradford, D., Blanc, P. ORCID: https://orcid.org/0000-0002-7318-8986, Bernardi, R., Benchetrit, S., Akindele, K. and Vassal, G.
European Journal of Cancer 190
: 112950.
September 2023
Protocol to dissociate healthy and infected murine- and hamster-derived lung tissue for single-cell transcriptome analysis.
Pennitz, P., Goekeri, C., Trimpert, J., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Ebenig, A., Weissfuss, C., Mühlebach, M.D., Witzenrath, M. and Nouailles, G. ORCID: https://orcid.org/0000-0003-1973-3119
STAR Protocols 4
(1): 101957.
17 March 2023
Mitochondrial DNA mutations as natural barcodes for lineage tracing of murine tumor models.
Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Ten Hacken, E., Southard, J. ORCID: https://orcid.org/0000-0002-3025-9406, Lareau, C. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Li, S., Neuberg, D.S. ORCID: https://orcid.org/0000-0003-2566-3145, Livak, K.J. ORCID: https://orcid.org/0000-0001-9105-5856 and Wu, C.J. ORCID: https://orcid.org/0000-0002-3348-5054
Cancer Research 83
(5): 667-672.
1 March 2023
High-resolution molecular atlas of a lung tumor in 3D.
Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Schallenberg, Simon, León-Periñán, D. ORCID: https://orcid.org/0000-0002-7970-0362, Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Theurillat, I. ORCID: https://orcid.org/0000-0002-1125-1951, Thomas, G., Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Fritzsche, S. ORCID: https://orcid.org/0000-0003-3335-3534, Nimo, J. ORCID: https://orcid.org/0000-0002-1565-7799, Ruff, L., Dernbach, G., Jurmeister, P., Murphy, S., Gregory, M., Liang, Y., Cordenonsi, M., Piccolo, S., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Klauschen, F. and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
bioRxiv
: 2023.05.10.539644.
10 May 2023
Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Petrović, S. ORCID: https://orcid.org/0000-0003-2238-8651, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Rami, B., Phan, M.H.Q., Panakova, D. ORCID: https://orcid.org/0000-0002-8739-6225 and Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850
Proceedings of the National Academy of Sciences of the United States of America 120
(4): e2208941120.
24 January 2023
H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma.
Phoyen, S., Sanpavat, A., Ma-on, C., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X, Hirankarn, N. ORCID: https://orcid.org/0000-0003-2224-6856, Tangkijvanich, P., Jindatip, D. ORCID: https://orcid.org/0000-0001-9825-2692, Whongsiri, P. ORCID: https://orcid.org/0000-0001-5263-9736 and Boonla, C. ORCID: https://orcid.org/0000-0002-6515-4321
Heliyon 9
(12): e22589.
December 2023
Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion.
Platzer, R., Hellmeier, J. ORCID: https://orcid.org/0000-0002-7153-9121, Göhring, J. ORCID: https://orcid.org/0000-0002-6755-5305, Perez, I.D., Schatzlmaier, P., Bodner, C. ORCID: https://orcid.org/0000-0001-5635-4842, Focke-Tejkl, M. ORCID: https://orcid.org/0000-0003-3433-5071, Schütz, G.J., Sevcsik, E., Stockinger, H. ORCID: https://orcid.org/0000-0001-6404-4430, Brameshuber, M. ORCID: https://orcid.org/0000-0001-8672-2255 and Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198
EMBO Reports 24
(11): e57842.
6 November 2023
The rate of spontaneous mutations in yeast deficient for MutSβ function.
Plavskin, Y. ORCID: https://orcid.org/0000-0002-6911-3009, de Biase, M.S. ORCID: https://orcid.org/0000-0003-0383-5161, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268 and Siegal, M.L. ORCID: https://orcid.org/0000-0001-6930-2988
G3 : Genes Genomes Genetics 13
(3): jkac330.
March 2023
Generation of TGFβR2(-1) neoantigen-specific HLA-DR4-restricted T cell receptors for cancer therapy.
Plewa, N. ORCID: https://orcid.org/0000-0002-5888-297X, Poncette, L. ORCID: https://orcid.org/0000-0001-8300-3968 and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Journal for ImmunoTherapy of Cancer 11
(2): e006001.
February 2023
Cox proportional hazards deep neural network identifies peripheral blood complete remission to be at least equivalent to morphologic complete remission in predicting outcomes of patients treated with azacitidine - a prospective cohort study by the AGMT.
Pleyer, L. ORCID: https://orcid.org/0000-0002-2790-5067, Vaisband, M., Drost, M., Pfeilstöcker, M., Stauder, R., Heibl, S., Sill, H. ORCID: https://orcid.org/0000-0003-0993-4371, Girschikofsky, M., Stampfl-Mattersberger, M., Pichler, A., Hartmann, B., Petzer, A., Schreder, M., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Vallet, S., Melchardt, T., Zebisch, A., Pichler, P., Zaborsky, N., Machherndl-Spandl, S., Wolf, D., Keil, F., Hasenauer, J., Larcher-Senn, J. and Greil, R.
American Journal of Hematology 98
(11): 1685-1698.
November 2023
Inversion polymorphism in a complete human genome assembly.
Porubsky, D., Harvey, W.T., Rozanski, A.N., Ebler, J., Höps, W., Ashraf, H., Hasenfeld, P., Paten, B., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Marschall, T., Korbel, J.O. and Eichler, E.E. ORCID: https://orcid.org/0000-0002-8246-4014
Genome Biology 24
(1): 100.
30 April 2023
Gaps and complex structurally variant loci in phased genome assemblies.
Porubsky, D., Vollger, M.R., Harvey, W.T., Rozanski, A.N., Ebert, P., Hickey, G., Hasenfeld, P., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Stober, C., Korbel, J.O., Paten, B., Marschall, T. and Eichler, E.E.
Genome Research 33
(4): 496-510.
April 2023
Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity.
Prigann, J., Postmus, D., Pietrobon, A.J., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Jansen, J., Möller, L., Fadejeva, J., Steijaert, T., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Koppe, U., Gunsenheimer-Bartmeyer, B., Meixenberger, K., Vitcetz, S.N., Sohn, M., Loyal, L., Thiel, A., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Sutter, K., Dittmer, U., Laue, M., Bannert, N., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Goffinet, C.
bioRxiv
: 2020.05.04.075119v3.
19 November 2023
Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.
Proft, S. ORCID: https://orcid.org/0000-0002-1707-0625, Leiz, J. ORCID: https://orcid.org/0000-0002-6531-7047, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Seelow, D. ORCID: https://orcid.org/0000-0002-9746-4412, Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142 and Rutkiewicz, M. ORCID: https://orcid.org/0000-0001-8339-3230
BMC Genomics 24
(1): 736.
4 December 2023
Cryo-EM captures early ribosome assembly in action.
Qin, B. ORCID: https://orcid.org/0000-0002-2503-7913, Lauer, S.M. ORCID: https://orcid.org/0000-0003-3518-5116, Balke, A. ORCID: https://orcid.org/0000-0001-8469-6911, Vieira-Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507, Bürger, J. ORCID: https://orcid.org/0000-0002-4326-5047, Mielke, T. ORCID: https://orcid.org/0000-0001-9275-3146, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Scheerer, P. ORCID: https://orcid.org/0000-0001-5028-2075, Spahn, C.M.T. ORCID: https://orcid.org/0000-0002-2939-9487 and Nikolay, R. ORCID: https://orcid.org/0000-0003-4713-2548
Nature Communications 14
(1): 898.
17 February 2023
A design strategy to generate a SARS-CoV-2 RBD vaccine that abrogates ACE2 binding and improves neutralizing antibody responses.
Ratswohl, C. ORCID: https://orcid.org/0000-0001-5413-0730, Vázquez García, C. ORCID: https://orcid.org/0000-0003-4583-7616, Ahmad, A.U.W. ORCID: https://orcid.org/0009-0003-0734-7904, Gonschior, H. ORCID: https://orcid.org/0000-0002-1775-8120, Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195, Silvis, C.E. ORCID: https://orcid.org/0009-0005-0433-2197, Spatt, L., Gerhard, C. ORCID: https://orcid.org/0000-0001-6956-7249, Lehmann, M. ORCID: https://orcid.org/0000-0002-8370-6353, Sander, L.E. ORCID: https://orcid.org/0000-0002-0476-9947, Kurth, F. ORCID: https://orcid.org/0000-0002-3807-473X, Olsson, S. ORCID: https://orcid.org/0000-0002-3927-7897 and de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157
European Journal of Immunology 53
(10): e2350408.
October 2023
Treatment of infants and children with SARS-CoV-2 monoclonal antibodies: a European case series.
Rau, C. ORCID: https://orcid.org/0000-0002-8173-1096, Auer-Hackenberg, L., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Schwabel, E., Jaros, M., Diederichs, A., Lehrnbecher, T., Holm, M., von Linstow, M.L., Martin, L., Dinges, S.S., Rothensteiner, M., Siepermann, M., Strenger, V., von Both, U. ORCID: https://orcid.org/0000-0001-8411-1071, Teig, N., Brinkmann, F., Leeb, F., Zeitlinger, M., Kobbe, R. and Götzinger, F. ORCID: https://orcid.org/0000-0002-1546-8111
Pediatric Infectious Disease Journal 42
(2): 125-129.
February 2023
Long-read sequencing of diagnosis and post-therapy medulloblastoma reveals complex rearrangement patterns and epigenetic signatures.
Rausch, T., Snajder, R., Leger, A., Simovic, M., Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Villacorta, L., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Fröhling, S., Stegle, O., Birney, E., Bonder, M.J. ORCID: https://orcid.org/0000-0002-8431-3180, Ernst, A. and Korbel, J.O.
Cell Genomics 3
(4): 100281.
12 April 2023
Cell adhesion and immune response, two main functions altered in the transcriptome of seasonally regressed testes of two mammalian species.
Real, F.M. ORCID: https://orcid.org/0000-0003-0692-2260, Lao-Pérez, M. ORCID: https://orcid.org/0000-0001-6707-6825, Burgos, M. ORCID: https://orcid.org/0000-0003-4446-9313, Mundlos, S. ORCID: https://orcid.org/0000-0002-9788-3166, Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X, Jiménez, R. ORCID: https://orcid.org/0000-0003-4103-8219 and Barrionuevo, F.J. ORCID: https://orcid.org/0000-0003-2651-1530
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 340
(3): 231-244.
May 2023
Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion.
Rejeski, K. ORCID: https://orcid.org/0000-0003-3905-0251, Perez, A., Iacoboni, G. ORCID: https://orcid.org/0000-0003-0805-9288, Blumenberg, V. ORCID: https://orcid.org/0000-0003-1379-0876, Bücklein, V.L. ORCID: https://orcid.org/0000-0001-7391-7280, Völkl, S. ORCID: https://orcid.org/0000-0003-2193-3048, Penack, O., Albanyan, O. ORCID: https://orcid.org/0000-0003-4802-5445, Stock, S. ORCID: https://orcid.org/0000-0002-5072-5013, Müller, F. ORCID: https://orcid.org/0000-0001-5487-5839, Karschnia, P. ORCID: https://orcid.org/0000-0002-1254-5310, Petrera, A., Reid, K. ORCID: https://orcid.org/0000-0002-6585-0781, Faramand, R. ORCID: https://orcid.org/0000-0001-7750-781X, Davila, M.L. ORCID: https://orcid.org/0000-0002-6270-3065, Modi, K. ORCID: https://orcid.org/0000-0003-3351-8829, Dean, E.A. ORCID: https://orcid.org/0000-0003-3153-223X, Bachmeier, C. ORCID: https://orcid.org/0000-0002-9832-3670, von Bergwelt-Baildon, M., Locke, F.L., Bethge, W. ORCID: https://orcid.org/0000-0001-6052-2618, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mackensen, A. ORCID: https://orcid.org/0000-0002-0685-4483, Barba, P. ORCID: https://orcid.org/0000-0003-1038-5197, Jain, M.D. ORCID: https://orcid.org/0000-0002-7789-1257 and Subklewe, M. ORCID: https://orcid.org/0000-0001-9154-9469
Science Advances 9
(38): eadg3919.
22 September 2023
Targeted treatment in a case series of AR+, HRAS/PIK3CA co-mutated salivary duct carcinoma.
Rieke, D.T., Schröder, S., Schafhausen, P., Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Zuljan, E., von der Emde, B., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Keilholz, U. and Klinghammer, K. ORCID: https://orcid.org/0000-0001-6425-4833
Frontiers in Oncology 13
: 1107134.
2023
Mutational topography reflects clinical neuroblastoma heterogeneity.
Rodriguez-Fos, Elias ORCID: https://orcid.org/0000-0002-2555-0178, Planas-Fèlix, Mercè, Burkert, Martin ORCID: https://orcid.org/0000-0002-6721-9985, Puiggròs, Montserrat, Toedling, Joern, Thiessen, Nina, Blanc, Eric ORCID: https://orcid.org/0000-0002-4369-0254, Szymansky, Annabell ORCID: https://orcid.org/0000-0003-4797-4526, Hertwig, Falk ORCID: https://orcid.org/0000-0003-4784-6516, Ishaque, Naveed ORCID: https://orcid.org/0000-0002-8426-901X, Beule, Dieter ORCID: https://orcid.org/0000-0002-3284-0632, Torrents, David, Eggert, Angelika, Koche, Richard P., Schwarz, Roland F. ORCID: https://orcid.org/0000-0001-9155-4268, Haase, Kerstin ORCID: https://orcid.org/0000-0002-0944-5618, Schulte, Johannes H. ORCID: https://orcid.org/0000-0003-0671-1201 and Henssen, Anton G. ORCID: https://orcid.org/0000-0003-1534-778X
[Dataset]
27 April 2023
Mutational topography reflects clinical neuroblastoma heterogeneity.
Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Planas-Fèlix, M., Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, Puiggròs, M., Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Thiessen, N., Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Torrents, D., Eggert, A., Koche, R.P., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Cell Genomics 3
(10): 100402.
11 October 2023
TapA acts as specific chaperone in TasA filament formation by strand complementation.
Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Lindemann, F. ORCID: https://orcid.org/0000-0002-5183-3120, Diehl, A. ORCID: https://orcid.org/0000-0001-7295-9972, Cremer, N., Higman, V.A. ORCID: https://orcid.org/0000-0002-3204-2665, Schlegel, B., Leidert, M., Driller, K., Turgay, K. ORCID: https://orcid.org/0000-0002-8959-492X, Schmieder, P. ORCID: https://orcid.org/0000-0001-9968-9327, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Oschkinat, H. ORCID: https://orcid.org/0000-0002-4384-9544
Proceedings of the National Academy of Sciences of the United States of America 120
(17): e2217070120.
25 April 2023
Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.
Rybak-Wolf, A. ORCID: https://orcid.org/0000-0002-1192-5290, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Oliveras Martinez, A. ORCID: https://orcid.org/0000-0002-5880-5245, Glažar, P. ORCID: https://orcid.org/0000-0003-0842-0088, Loewa, A. ORCID: https://orcid.org/0000-0002-5551-731X, Kim, S.J. ORCID: https://orcid.org/0000-0001-8357-0073, Kaufer, B.B. ORCID: https://orcid.org/0000-0003-1328-2695, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Nature Microbiology 8
(7): 1252-1266.
July 2023
Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer.
Saini, M. ORCID: https://orcid.org/0000-0002-5916-8516, Schmidleitner, L., Moreno, H.D., Donato, E. ORCID: https://orcid.org/0000-0003-3541-9170, Falcone, M., Bartsch, J.M., Klein, C., Vogel, V., Würth, R., Pfarr, N. ORCID: https://orcid.org/0000-0002-5977-5375, Espinet, E., Lehmann, M., Königshoff, M., Reitberger, M., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Graf, E., Schwarzmayr, T., Strom, T.M., Spaich, S., Sütterlin, M., Schneeweiss, A., Weichert, W., Schotta, G., Reichert, M., Aceto, N., Sprick, M.R., Trumpp, A. and Scheel, C.H.
Cell Reports 42
(6): 112533.
27 June 2023
Pre-operative radiotherapy is associated with superior local relapse-free survival in advanced synovial sarcoma.
Scheer, M. ORCID: https://orcid.org/0000-0002-0665-6268, Hallmen, E., Vokuhl, C., Fuchs, J., Tunn, P.U., Münter, M., Timmermann, B., Bauer, S., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Eggert, A., Klingebiel, T. and Koscielniak, E.
Journal of Cancer Research and Clinical Oncology 149
(5): 1717-1731.
May 2023
Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Cauchy, P. ORCID: https://orcid.org/0000-0002-0659-0799, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Giefing, M., Fornes, O. ORCID: https://orcid.org/0000-0002-5969-3054, Vankadari, N. ORCID: https://orcid.org/0000-0001-9363-080X, Assi, S.A., Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Weniger, M.A., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Anagnostopoulos, I. ORCID: https://orcid.org/0000-0002-5043-6043, Bukur, T., Casarotto, M.G. ORCID: https://orcid.org/0000-0002-0571-7671, Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Edginton-White, B., Gebhardt, J.C.M. ORCID: https://orcid.org/0000-0003-1900-600X, Grau, M., Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Hansmann, M.L., Hartmann, S. ORCID: https://orcid.org/0000-0003-3424-1091, Huber, L., Kärgel, E., Lusatis, S., Noerenberg, D., Obier, N., Pannicke, U. ORCID: https://orcid.org/0000-0002-0929-1794, Fischer, A. ORCID: https://orcid.org/0000-0002-7145-2544, Reisser, A., Rosenwald, A., Schwarz, K. ORCID: https://orcid.org/0000-0003-3178-5990, Sundararaj, S., Weilemann, A. ORCID: https://orcid.org/0009-0001-1340-6486, Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Xu, W., Lenz, G. ORCID: https://orcid.org/0000-0002-4728-1693, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Wasserman, W.W. ORCID: https://orcid.org/0000-0001-6098-6412, Cockerill, P.N. ORCID: https://orcid.org/0000-0002-4410-8174, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Siebert, R., Küppers, R., Grosschedl, R. ORCID: https://orcid.org/0000-0002-0058-1250, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Bonifer, C. ORCID: https://orcid.org/0000-0002-4267-0825 and Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413
Nature Communications 14
(1): 6947.
7 November 2023
COVID-19 and cellular senescence.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Tchkonia, T., Niedernhofer, L.J., Robbins, P.D. ORCID: https://orcid.org/0000-0003-1068-7099, Kirkland, J.L. ORCID: https://orcid.org/0000-0003-1676-4905 and Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931
Nature Reviews Immunology 23
(4): 251-263.
April 2023
Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen.
Schmutz, M., Zucknick, M., Schlenk, R.F., Mertens, D., Benner, A., Weichenhan, D., Mücke, O., Döhner, K., Plass, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Claus, R.
Clinical Epigenetics 15
(1): 171.
26 October 2023
Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J. ORCID: https://orcid.org/0000-0001-8810-0492, Sundaravinayagam, D. ORCID: https://orcid.org/0000-0003-0717-7530, Blume, A. ORCID: https://orcid.org/0000-0003-3045-8234, Marg, A. ORCID: https://orcid.org/0000-0003-3673-4244, Grunwald, S. ORCID: https://orcid.org/0000-0002-3899-5424, Metzler, E. ORCID: https://orcid.org/0000-0003-1735-6364, Escobar, H. ORCID: https://orcid.org/0000-0002-8128-7845, Müthel, S. ORCID: https://orcid.org/0000-0002-3525-8859, Wang, H. ORCID: https://orcid.org/0000-0003-3720-3859, Wollersheim, T. ORCID: https://orcid.org/0000-0002-3170-0996, Weber-Carstens, S., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793, Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
International Journal of Molecular Sciences 24
(3): 2772.
1 February 2023
Target selection for T-cell therapy in epithelial ovarian cancer: systematic prioritization of self-antigens.
Schossig, P. ORCID: https://orcid.org/0000-0001-5017-3602, Coskun, E., Arsenic, R., Horst, D., Sehouli, J. ORCID: https://orcid.org/0000-0002-5963-6623, Bergmann, E., Andresen, N., Sigler, C. ORCID: https://orcid.org/0000-0003-3229-4122, Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Ochsenreither, S. ORCID: https://orcid.org/0000-0001-6024-4312
International Journal of Molecular Sciences 24
(3): 2292.
24 January 2023
Treatment of adult ALL patients with third-generation CD19-directed CAR T cells: results of a pivotal trial.
Schubert, M.L., Schmitt, A., Hückelhoven-Krauss, A., Neuber, B., Kunz, A., Waldhoff, P., Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Yousefian, S., Jopp-Saile, L., Wang, L., Korell, F., Keib, A., Michels, B., Haas, D., Sauer, T., Derigs, P., Kulozik, A., Kunz, J., Pavel, P., Laier, S., Wuchter, P., Schmier, J., Bug, G., Lang, F., Gökbuget, N., Casper, J., Görner, M., Finke, J., Neubauer, A., Ringhoffer, M., Wolleschak, D., Brüggemann, M., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Ho, A.D., Müller-Tidow, C., Dreger, P. and Schmitt, M.
Journal of Hematology & Oncology 16
(1): 79.
22 July 2023
The cytomegalovirus M35 protein directly binds to the interferon-β enhancer and modulates transcription of (Ifnb1) and other IRF3-driven genes.
Schwanke, H. ORCID: https://orcid.org/0000-0001-9252-3594, Gonçalves Magalhães, V. ORCID: https://orcid.org/0000-0002-4593-3467, Schmelz, S. ORCID: https://orcid.org/0000-0002-2511-7593, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Hennig, T. ORCID: https://orcid.org/0000-0002-7788-1681, Günther, T. ORCID: https://orcid.org/0000-0001-9650-0218, Grundhoff, A., Dölken, L., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, van Ham, M., Jänsch, L., Büssow, K. ORCID: https://orcid.org/0000-0003-2031-5942, van den Heuvel, J. ORCID: https://orcid.org/0000-0001-5085-4010, Blankenfeldt, W. ORCID: https://orcid.org/0000-0001-9886-9668, Friedel, C.C. ORCID: https://orcid.org/0000-0003-3569-4877, Erhard, F. ORCID: https://orcid.org/0000-0002-3574-6983 and Brinkmann, M.M. ORCID: https://orcid.org/0000-0001-5431-6527
Journal of Virology 97
(6): e0040023.
29 June 2023
Cantharidin and its analogue norcantharidin inhibit metastasis-inducing genes S100A4 and MACC1.
Schöpe, P.C. ORCID: https://orcid.org/0000-0002-5512-8832, Zinnow, V., Ishfaq, M.A., Smith, J., Herrmann, P., Shoemaker, R.H., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
International Journal of Molecular Sciences 24
(2): 1179.
7 January 2023
The interactive complex between cytomegalovirus kinase vCDK/pUL97 and host factors CDK7-cyclin H determines individual patterns of transcription in infected cells.
Schütz, M., Cordsmeier, A., Wangen, C., Horn, A.H.C. ORCID: https://orcid.org/0000-0003-3539-8103, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Ensser, A. ORCID: https://orcid.org/0000-0001-8873-3863, Sticht, H. ORCID: https://orcid.org/0000-0001-5644-045X and Marschall, M.
International Journal of Molecular Sciences 24
(24): 17421.
13 December 2023
Broadening the phenotypic and molecular spectrum of FINCA syndrome: Biallelic NHLRC2 variants in 15 novel individuals.
Sczakiel, H.L. ORCID: https://orcid.org/0000-0003-3836-163X, Zhao, M., Wollert-Wulf, B. ORCID: https://orcid.org/0009-0000-0257-4049, Danyel, M., Ehmke, N., Stoltenburg, C., Damseh, N., Al-Ashhab, M., Balci, T.B. ORCID: https://orcid.org/0000-0002-5409-8387, Osmond, M., Andrade, A., Schallner, J., Porrmann, J., McDonald, K., Liao, M., Oppermann, H. ORCID: https://orcid.org/0000-0001-9216-5918, Platzer, K. ORCID: https://orcid.org/0000-0001-6127-6308, Dierksen, N., Mojarrad, M., Eslahi, A., Bakaeean, B., Calame, D.G., Lupski, J.R. ORCID: https://orcid.org/0000-0001-9907-9246, Firoozfar, Z., Seyedhassani, S.M., Mohammadi, S.A., Anwaar, N., Rahman, F. ORCID: https://orcid.org/0000-0003-1312-1007, Seelow, D. ORCID: https://orcid.org/0000-0002-9746-4412, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Horn, D., Maroofian, R. ORCID: https://orcid.org/0000-0001-6763-1542 and Boschann, F. ORCID: https://orcid.org/0000-0001-9410-9290
European Journal of Human Genetics 31
(8): 905-317.
August 2023
GIPC1 regulates MACC1-driven metastasis.
Siegel, F., Schmidt, H., Juneja, M., Smith, J., Herrmann, P., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Sharma, K., Fichtner, I., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Volkmer, R., Rathjen, F.G. ORCID: https://orcid.org/0000-0001-5351-613X, Schlag, P.M. and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Frontiers in Oncology 13
: 1280977.
8 December 2023
Systematic perturbation of chromatin factors identifies regulatory networks during healthy and malignant hematopoiesis.
Solé-Boldo, L. ORCID: https://orcid.org/0000-0002-6974-9066 and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Nature Genetics 55
(9): 1430-1431.
September 2023
Structure-based design of xanthine-imidazopyridines and -imidazothiazoles as highly potent and in vivo efficacious tryptophan hydroxylase inhibitors.
Specker, E. ORCID: https://orcid.org/0000-0002-9471-9520, Wesolowski, R. ORCID: https://orcid.org/0009-0002-7228-1051, Schütz, A. ORCID: https://orcid.org/0000-0002-0606-2574, Matthes, S., Mallow, K., Wasinska-Kalwa, M., Winkler, L. ORCID: https://orcid.org/0000-0003-3350-1189, Oder, A., Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Pleimes, D., von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330
Journal of Medicinal Chemistry 66
(21): 14866-14896.
9 November 2023
Consensus molecular subtypes as biomarkers of fluorouracil and folinic acid maintenance therapy with or without panitumumab in (RAS) wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212).
Stahler, A., Hoppe, B., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Keilholz, L., Müller, L., Karthaus, M., Fruehauf, S., Graeven, U., Fischer von Weikersthal, L., Goekkurt, E., Kasper, S., Kind, A.J., Kurreck, A., Alig, A.H.S., Held, S., Reinacher-Schick, A., Heinemann, V., Horst, D., Jarosch, A., Stintzing, S., Trarbach, T. and Modest, D.P.
Journal of Clinical Oncology 41
(16): 2975-2987.
1 June 2023
CYCLeR - a novel tool for the full isoform assembly and quantification of circRNAs.
Stefanov, S.R. ORCID: https://orcid.org/0000-0003-4341-8725 and Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479
Nucleic Acids Research 51
(2): e10.
25 January 2023
Doxorubicin changes the spatial organization of the genome around active promoters.
Stefanova, M.E. ORCID: https://orcid.org/0000-0002-4419-2839, Ing-Simmons, E. ORCID: https://orcid.org/0000-0002-0394-2429, Stefanov, S. ORCID: https://orcid.org/0000-0003-4341-8725, Flyamer, I., Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Schöpflin, R., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Vaquerizas, J.M. and Mundlos, S.
Cells 12
(15): 2001.
4 August 2023
A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity.
Stern, D., Meyer, T.C., Treindl, F., Mages, H.W., Krüger, M., Skiba, M., Krüger, J.P., Zobel, C.M., Schreiner, M., Grossegesse, M., Rinner, T., Peine, C., Stoliaroff-Pépin, A., Harder, T., Hofmann, N., Michel, J., Nitsche, A., Stahlberg, S., Kneuer, A., Sandoni, A., Kubisch, U., Schlaud, M., Mankertz, A., Schwarz, T., Corman, V.M., Müller, M.A., Drosten, C., de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157, Schaade, L., Dorner, M.B. and Dorner, B.G.
Scientific Reports 13
(1): 21846.
9 December 2023
Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Straube, J. ORCID: https://orcid.org/0000-0002-1748-0659, Eifert, T., Vu, T. ORCID: https://orcid.org/0000-0003-2831-2957, Janardhanan, Y., Haldar, R., von Eyss, B., Cooper, L., Bruedigam, C., Ling, V.Y. ORCID: https://orcid.org/0000-0001-9757-1229, Cooper, E., Patch, A.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schnoeder, T.M., Bywater, M., Heidel, F.H. and Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209
Leukemia 37
(4): 741-750.
April 2023
SMITH: spatially constrained stochastic model for simulation of intra-tumour heterogeneity.
Streck, A. ORCID: https://orcid.org/0000-0002-7302-0147, Kaufmann, T.L. ORCID: https://orcid.org/0000-0003-4374-1338 and Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268
Bioinformatics 39
(3): btad102.
March 2023
Sarcoma patients admitted to the intensive care unit (ICU): predictive relevance of common sepsis and performance parameters.
Striefler, J.K., Binder, P.T., Brandes, F., Rau, D., Wittenberg, S., Kaul, D., Roohani, S., Jarosch, A. ORCID: https://orcid.org/0000-0002-6040-394X, Schäfer, F.M., Öllinger, R. ORCID: https://orcid.org/0000-0002-4499-1673, Märdian, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Eckardt, K.U., Kruse, J. and Flörcken, A.
Cancer Management and Research 15
: 321-334.
27 March 2023
Stress-induced nuclear speckle reorganization is linked to activation of immediate early gene splicing.
Sung, H.M. ORCID: https://orcid.org/0000-0001-6498-4254, Schott, J. ORCID: https://orcid.org/0000-0002-2684-1305, Boss, P. ORCID: https://orcid.org/0000-0002-5459-9771, Lehmann, J.A. ORCID: https://orcid.org/0000-0002-3319-1558, Hardt, M.R. ORCID: https://orcid.org/0009-0004-8131-9175, Lindner, D. ORCID: https://orcid.org/0009-0001-6214-7951, Messens, J. ORCID: https://orcid.org/0000-0002-2128-8264, Bogeski, I. ORCID: https://orcid.org/0000-0001-9879-7174, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Stoecklin, G. ORCID: https://orcid.org/0000-0001-9284-9834
Journal of Cell Biology 222
(12): e202111151.
4 December 2023
A fucoidan plant drink reduces Helicobacter pylori load in the stomach: a real-world study.
Teng, Q.L., Sui, S.J., Zhu, Z., Gao, Q., Ge, H., Wang, K.Q., Lino-Silva, L.S., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, White, J.R., Peng, Q.H. and Wei, Y.Z.
Translational Gastroenterology and Hepatology 8
: 34-34.
30 October 2023
Radiation and dose-densification of R-CHOP in aggressive B-cell lymphoma with intermediate prognosis: the UNFOLDER study.
Thurner, Lorenz, Ziepert, Marita, Berdel, Christian, Schmidt, Christian, Borchmann, Peter, Kaddu-Mulindwa, Dominic, Viardot, Andreas, Witzens-Harig, Mathias, Dierlamm, Judith, Haenel, Mathias, Metzner, Bernd, Wulf, Gerald, Lengfelder, Eva, Keller, Ulrich B. ORCID: https://orcid.org/0000-0002-8485-1958, Frickhofen, Norbert, Nickelsen, Maike, Gaska, Tobias, Griesinger, Frank, Mahlberg, Rolf, Marks, Reinhard, Shpilberg, Ofer, Lindemann, Hans-Walter, Soekler, Martin, Fischer von Weikersthal, Ludwig, Kiehl, Michael, Roemer, Eva, Bentz, Martin, Krammer-Steiner, Beate, Trappe, Ralf, de Nully Brown, Peter, Federico, Massimo, Merli, Francesco, Engelhard, Marianne, Glass, Bertram, Schmitz, Norbert, Truemper, Lorenz, Bewarder, Moritz, Hartmann, Frank, Murawski, Niels, Stilgenbauer, Stephan, Rosenwald, Andreas, Altmann, Bettina, Schmidberger, Heinz, Fleckenstein, Jochen, Loeffler, Markus, Poeschel, Viola and Held, Gerhard
HemaSphere 7
(7): e904.
July 2023
Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
Torcal Garcia, G. ORCID: https://orcid.org/0000-0002-0843-7296, Kowenz-Leutz, E., Tian, T.V ORCID: https://orcid.org/0000-0002-9906-0980, Klonizakis, A., Lerner, J., De Andres-Aguayo, L., Sapozhnikova, V., Berenguer, C., Carmona, M.P., Casadesus, M.V., Bulteau, R. ORCID: https://orcid.org/0000-0002-9128-8809, Francesconi, M., Peiro, S., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Zaret, K., Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X and Graf, T. ORCID: https://orcid.org/0000-0003-2774-4117
eLife 12
: e83951.
27 June 2023
Application of a spacer-nick gene-targeting approach to repair disease-causing mutations with increased safety.
Tran, N.T. ORCID: https://orcid.org/0000-0003-0896-8641, Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195, Danner, E. ORCID: https://orcid.org/0000-0003-3277-5727, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696
Bio-protocol 13
(8): e4661.
20 April 2023
CORUM: the comprehensive resource of mammalian protein complexes-2022.
Tsitsiridis, G., Steinkamp, R., Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Brauner, B., Fobo, G., Frishman, G., Montrone, C. and Ruepp, A. ORCID: https://orcid.org/0000-0003-1705-3515
Nucleic Acids Research 51
(D1): D539-D545.
6 January 2023
e-RNA: a collection of web-servers for the prediction and visualisation of RNA secondary structure and their functional features.
Tsybulskyi, V. ORCID: https://orcid.org/0009-0002-4141-6291, Semenchenko, E. ORCID: https://orcid.org/0009-0007-5306-076X and Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479
Nucleic Acids Research 51
(W1): W160-W167.
5 July 2023
A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P., Orgeur, M., Comai, G., Poehle-Kronnawitter, S., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Gloger, M. ORCID: https://orcid.org/0000-0002-3319-7642, Dumas, C.E., Giesecke-Thiel, C., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Tajbakhsh, S., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Stricker, S.
Immunity 56
(6): 1204-1219.
13 June 2023
Clonally expanded PD-1-expressing T cells are enriched in synovial fluid of juvenile idiopathic arthritis patients.
Vanni, A., Mazzoni, A., Semeraro, R., Capone, M., Maschmeyer, P. ORCID: https://orcid.org/0000-0002-1705-5302, Lamacchia, G., Salvati, L. ORCID: https://orcid.org/0000-0001-5831-0392, Carnasciali, A., Farahvachi, P., Giani, T., Simonini, G., Filocamo, G., Romano, M., Liotta, F., Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Cosmi, L. ORCID: https://orcid.org/0000-0002-8150-8177, Cimaz, R., Magi, A., Maggi, L. and Annunziato, F. ORCID: https://orcid.org/0000-0001-8798-7589
European Journal of Immunology 53
(7): 2250162.
July 2023
Harnessing CD3 diversity to optimize CAR T cells.
Velasco Cárdenas, R.M.H., Brandl, S.M. ORCID: https://orcid.org/0000-0002-1632-0127, Meléndez, A.V., Schlaak, A.E., Buschky, A., Peters, T., Beier, F., Serrels, B., Taromi, S. ORCID: https://orcid.org/0000-0001-5657-6568, Raute, K., Hauri, S. ORCID: https://orcid.org/0000-0002-7249-2011, Gstaiger, M., Lassmann, S., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Boerries, M. ORCID: https://orcid.org/0000-0002-3670-0602, Andrieux, G., Bengsch, B. ORCID: https://orcid.org/0000-0003-2552-740X, Schamel, W.W. ORCID: https://orcid.org/0000-0003-4496-3100 and Minguet, S. ORCID: https://orcid.org/0000-0001-8211-5538
Nature Immunology 24
(12): 2135-2149.
December 2023
Daratumumab as a novel treatment option in refractory ITP.
Vernava, I. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood Cells Molecules and Diseases 99
: 102724.
March 2023
Increased mutation and gene conversion within human segmental duplications.
Vollger, M.R., Dishuck, P.C., Harvey, W.T., DeWitt, W.S., Guitart, X., Goldberg, M.E., Rozanski, A.N., Lucas, J., Asri, M., Munson, K.M., Lewis, A.P., Hoekzema, K., Logsdon, G.A., Porubsky, D., Paten, B., Harris, K., Hsieh, P.H. and Eichler, E.E.
Nature 617
(7960): 325-334.
11 May 2023
Getting to the root of branched ubiquitin chains: a review of current methods and functions.
Waltho, A. ORCID: https://orcid.org/0009-0000-0059-9357 and Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202
Methods in Molecular Biology 2602
: 19-38.
2023
Impact of perioperative dexamethasone in the context of neurosurgical brain metastasis resection.
Wasilewski, D. ORCID: https://orcid.org/0000-0001-6505-0584, Bukatz, J., Peukert, R., Shaked, Z., Poeser, P., Karbe, A.G., Trelinska-Finger, A., Jelgersma, C., Früh, A., Raspe, M., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Capper, D., Schlaak, M., Thuss-Patience, P., Bischoff, P., Horst, D., Krenzke, M., Xu, R. ORCID: https://orcid.org/0000-0003-1906-8489, Ehret, F. ORCID: https://orcid.org/0000-0001-6177-1755, Kaul, D., Misch, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Frost, N., Vajkoczy, P. and Onken, J.
medRxiv
: 2023.01.23.23284887.
25 January 2023
Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.
Watkins, T.B.K. ORCID: https://orcid.org/0000-0001-7414-737X, Colliver, E.C., Huska, M.R. ORCID: https://orcid.org/0000-0002-0912-745X, Kaufmann, T.L. ORCID: https://orcid.org/0000-0003-4374-1338, Lim, E.L., Duncan, C.B. ORCID: https://orcid.org/0000-0003-3127-228X, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Van Loo, P., Swanton, C., McGranahan, N. and Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268
PLoS Computational Biology 19
(10): e1011379.
23 October 2023
PEDL+: Protein-centered relation extraction from PubMed at your fingertip.
Weber, L. ORCID: https://orcid.org/0000-0002-2499-472X, Barth, F., Lorenz, L. ORCID: https://orcid.org/0000-0002-1471-5782, Konrath, F. ORCID: https://orcid.org/0000-0002-6843-6252, Huska, K., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868 and Leser, U.
Bioinformatics 39
(11): btad603.
November 2023
Gene editing in mouse zygotes using the CRISPR/Cas9 system.
Wefers, B., Wurst, W. and Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803
Methods in Molecular Biology 2631
: 207-230.
2023
Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Weigert, R., Hetzel, S. ORCID: https://orcid.org/0000-0002-4783-3814, Bailly, N., Haggerty, C., Ilik, I.A., Yung, P.Y.K., Navarro, C., Bolondi, A. ORCID: https://orcid.org/0000-0002-1096-9435, Kumar, A.S. ORCID: https://orcid.org/0000-0001-7918-6706, Anania, C. ORCID: https://orcid.org/0000-0003-1549-4157, Brändl, B., Meierhofer, D., Lupianez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X, Müller, F.J. ORCID: https://orcid.org/0000-0001-9478-8430, Aktas, T. ORCID: https://orcid.org/0000-0003-1599-9454, Elsässer, S.J. ORCID: https://orcid.org/0000-0001-8724-4849, Kretzmer, H., Smith, Z.D. ORCID: https://orcid.org/0000-0002-9283-1957 and Meissner, A. ORCID: https://orcid.org/0000-0001-8646-7469
Nature Cell Biology 25
: 579–591.
April 2023
Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial.
Weller, J. ORCID: https://orcid.org/0000-0001-5818-5392, Schäfer, N., Schaub, C., Tzaridis, T. ORCID: https://orcid.org/0000-0001-9651-1144, Zeyen, T., Schneider, M. ORCID: https://orcid.org/0000-0002-6025-7479, Potthoff, A.L. ORCID: https://orcid.org/0000-0002-5710-6557, Giordano, F.A., Steinbach, J.P., Zeiner, P.S., Kowalski, T., Sabel, M., Hau, P., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Tabatabai, G. ORCID: https://orcid.org/0000-0002-3542-8782, Ringel, F. ORCID: https://orcid.org/0000-0003-3132-7543, Schmidt-Graf, F., Brehmer, S., Tonn, J.C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Vajkoczy, P., Glas, M., Vatter, H., Herrlinger, U. and Seidel, C.
Journal of Neuro-Oncology 161
(1): 147-153.
January 2023
Mouse models of human multiple myeloma subgroups.
Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Farré Díaz, C. ORCID: https://orcid.org/0000-0003-4306-2108, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Napieczynska, H. ORCID: https://orcid.org/0000-0001-5091-1185, Langner, P. ORCID: https://orcid.org/0009-0007-4313-3152, Werner, M. ORCID: https://orcid.org/0000-0003-1200-807X, Walter, B. ORCID: https://orcid.org/0000-0002-0844-5958, Wollert-Wulf, B. ORCID: https://orcid.org/0009-0000-0257-4049, Yasuda, T. ORCID: https://orcid.org/0000-0001-9997-6852, Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Anagnostopoulos, I., Rosenwald, A., Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044
Proceedings of the National Academy of Sciences of the United States of America 120
(10): e2219439120.
7 March 2023
Association of helicobacter pylori positivity with risk of disease and mortality.
Wizenty, J., Koop, P.H., Clusmann, J., Tacke, F., Trautwein, C., Schneider, K.M., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Schneider, C.V.
Clinical and Translational Gastroenterology 14
(9): e00610.
September 2023
Prävention von Infektionskrankheiten mit Abwasser [Prevention of Infectious Diseases with Wastewater].
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
Arbeitsmedizin Sozialmedizin Umweltmedizin 58
(6): 381-384.
June 2023
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.
Xiong, E. ORCID: https://orcid.org/0000-0001-5124-6922, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Salomon, C. ORCID: https://orcid.org/0009-0000-6723-6497, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696
Frontiers in Immunology 13
: 1083119.
5 January 2023
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Yan, S., Schöpe, P.C. ORCID: https://orcid.org/0000-0002-5512-8832, Lewis, J., Putzker, K., Uhrig, U., Specker, E. ORCID: https://orcid.org/0000-0002-9471-9520, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Lindemann, P. ORCID: https://orcid.org/0000-0002-8224-3764, Omran, A., Sanchez-Ibarra, H.E. ORCID: https://orcid.org/0000-0002-9991-267X, Unger, A., Zischinsky, M.L., Klebl, B., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Biomedicine & Pharmacotherapy 168
: 115698.
December 2023
What do you most hope spatial molecular profiling will help us understand? Part 2.
Yanai, I., Fertig, E.J., Li, M., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Klughammer, J., Nie, Q., Chen, J. and Coskun, A.F.
Cell Systems 14
(7): 543-546.
19 July 2023
Response to anti-SARS-CoV-2 mRNA vaccines in multiple myeloma and chronic lymphocytic leukemia patients.
Zaleska, J., Kwasnik, P., Paziewska, M., Purkot, Jo., Szabelak, A., Jurek, M., Masny, N., Dziatkiewicz, I., Pronobis-Szczylik, B., Piebiak, A., Szymczyk, A., Jarosz-Chudzik, K., Bolkun, L., Kozlowska, K., Piszcz, J., Subocz, E., Halka, J., Bator, M., Kalicinska, E., Wrobel, T., Usnarska-Zubkiewicz, L., Rybka, J., Deren-Wagemann, I., Szyca-Smieszniak, M., Dybko, J., Hus, I., Pula, B., Cichocka, E., Rymko, M., Zdunczyk, D., Ziarkiewicz, M., Basak, G.W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Giannopoulos, K. ORCID: https://orcid.org/0000-0003-0135-4030
International Journal of Cancer 15
(4): 705-712.
15 February 2023
Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19.
Zhang, B., Zhang, Z., Koeken, V.A.C.M., Kumar, S., Aillaud, M., Tsay, H.C., Liu, Z., Kraft, A.R.M., Soon, C.F., Odak, I., Bošnjak, B., Vlot, A. ORCID: https://orcid.org/0000-0001-9538-987X, Swertz, M.A., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Geffers, R., Illig, T., Huehn, J., Saliba, A.E., Sander, L.E., Förster, R., Xu, C.J., Cornberg, M., Schulte, L.N. and Li, Y.
Cell Genomics 3
(2): 100232.
8 February 2023
LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cells.
Zhang, J., Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Li, X. ORCID: https://orcid.org/0000-0002-1173-1066, Gieselmann, L., de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157, Stecklum, M., Klein, F., Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Frontiers in Immunology 14
: 1331730.
19 December 2023
Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
Zhang, L. ORCID: https://orcid.org/0000-0001-9793-4632, Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Patra, U., Stroh, J., Isaakidis, K., Rieger, L., Kossatz, S. ORCID: https://orcid.org/0000-0002-1908-1782, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Zang, C., Demel, U. ORCID: https://orcid.org/0000-0002-6480-4185, Keiten-Schmitz, J., Wagner, K., Steiger, K., Rad, R., Bassermann, F. ORCID: https://orcid.org/0000-0003-4435-2609, Müller, S., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611
EMBO Molecular Medicine 15
(9): e16431.
September 2023
Tumour mutational burden and survival with molecularly matched therapy.
de Bortoli, T., Benary, M. ORCID: https://orcid.org/0000-0002-3067-2030, Horak, P., Lamping, M., Stintzing, S., Tinhofer, I., Leyvraz, S., Schäfer, R., Klauschen, F., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Stenzinger, A., Fröhling, S., Kurzrock, R., Keilholz, U., Rieke, D.T. and Jelas, I.
European Journal of Cancer 190
: 112925.
September 2023
Pandemieforschung: von Autoantikörpern und Impfstoff-Innovationen.
de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157
BIOspektrum 29
(6): 614-616.
October 2023
New MERS-CoV Vaccine.
Max Delbrueck Centrum fuer Molekulare in der Helmholtz Gemeinschaft.
22164013.9.
27 September 2023
Biliary microbial patterns in primary sclerosing cholangitis are linked to poorer transplant-free survival.
Özdirik, B. ORCID: https://orcid.org/0000-0002-8885-737X, Scherf, M., Brumercek, A., Nicklaus, J.M., Kruis, T., Haber, P.K., Pratschke, J., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Hepatology Communications 7
(6): e0156.
June 2023
2022
Gene therapy of cancer : methods and protocols.
Walther, Wolfgang, ed.
Methods in Molecular Biology, 2521
(3).
Springer / Humana Press, New York, NY.
ISBN 9781071624401
2022
A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4(+) T cells and is defective in Crohn's disease patients.
Ahlers, J., Mantei, A., Lozza, L., Stäber, M., Heinrich, F., Bacher, P., Hohnstein, T., Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Yüz, S.G., Alvarez-Simon, D., Bickenbach, A.R., Weidinger, C., Mockel-Tenbrinck, N., Kühl, A.A., Siegmund, B., Maul, J., Neumann, C. and Scheffold, A. ORCID: https://orcid.org/0000-0002-0626-343X
Mucosal Immunology 15
(3): 480-490.
May 2022
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H. ORCID: https://orcid.org/0000-0001-6903-3001, Flórez, A.F. ORCID: https://orcid.org/0000-0002-3063-0578, Kreth, S., Brückner, L.M., Yildiz, U. ORCID: https://orcid.org/0000-0002-7175-362X, Gartlgruber, M., Odoni, D.I., Poschet, G. ORCID: https://orcid.org/0000-0002-5344-0865, Garbowicz, K., Shao, C., Klein, C., Meier, J., Zeisberger, P., Nadler-Holly, M., Ziehm, M. ORCID: https://orcid.org/0000-0001-7074-4054, Paul, F., Burhenne, J., Bell, E., Shaikhkarami, M., Würth, R. ORCID: https://orcid.org/0000-0002-8156-6756, Stainczyk, S.A. ORCID: https://orcid.org/0000-0003-3746-7010, Wecht, E.M., Kreth, J., Büttner, M., Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X, Schlesner, M., Nicke, B., Stresemann, C., Llamazares-Prada, M., Reiling, J.H., Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242, Amit, I. ORCID: https://orcid.org/0000-0003-2968-877X, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Herrmann, C. ORCID: https://orcid.org/0000-0003-4989-4722, Wölfl, S., Henrich, K.O., Höfer, T. ORCID: https://orcid.org/0000-0003-3560-8780, Trumpp, A. ORCID: https://orcid.org/0000-0003-1584-3636 and Westermann, F.
Nature Cancer 3
(4): 471-485.
28 April 2022
Determinants of expression of SARS-CoV-2 entry related genes in upper and lower airways.
Aliee, H., Massip, F. ORCID: https://orcid.org/0000-0001-5855-0935, Qi, C. ORCID: https://orcid.org/0000-0003-3825-5802, de Biase, M.S. ORCID: https://orcid.org/0000-0003-0383-5161, van Nijnatten, J., Kersten, E.T.G., Kermani, N.Z., Khuder, B., Vonk, J.M., Vermeulen, R.C.H., Neighbors, M., Tew, G.W., Grimbaldeston, M.A., Ten Hacken, N.H.T., Hu, S., Guo, Y., Zhang, X. ORCID: https://orcid.org/0000-0002-6033-0525, Sun, K., Hiemstra, P.S., Ponder, B.A., Mäkelä, M.J., Malmström, K., Rintoul, R.C., Reyfman, P.A. ORCID: https://orcid.org/0000-0002-6435-6001, Theis, F.J., Brandsma, C.A., Adcock, I.M., Timens, W., Xu, C.J., van den Berge, M., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Koppelman, G.H., Nawijn, M.C. and Faiz, A.
Allergy 77
(2): 690-694.
February 2022
The monocyte, a maestro in the tumor microenvironment (TME) of breast cancer.
Amer, H.T., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and El Tayebi, H.M. ORCID: https://orcid.org/0000-0002-6896-6018
Cancers 14
(21): 5460.
7 November 2022
In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C. ORCID: https://orcid.org/0000-0003-1549-4157, Acemel, R.D. ORCID: https://orcid.org/0000-0003-4120-0140, Jedamzick, J., Bolondi, A. ORCID: https://orcid.org/0000-0002-1096-9435, Cova, G., Brieske, N., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Wittler, L., Real, F.M. ORCID: https://orcid.org/0000-0003-0692-2260 and Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X
Nature Genetics 54
(7): 1026-1036.
July 2022
De novo whole genome assembly of the Roborovski dwarf hamster (Phodopus roborovskii) genome, an animal model for severe/critical COVID-19.
Andreotti, S. ORCID: https://orcid.org/0000-0001-7678-9720, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Nouailles, G., Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Bieniara, M., Trimpert, J. and Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806
Genome Biology and Evolution 14
(7): evac100.
July 2022
Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming.
Anh, L.P.H., Nishimura, K. ORCID: https://orcid.org/0000-0002-0716-4142, Kuno, A. ORCID: https://orcid.org/0000-0002-4674-6882, Nguyen, T.L., Kato, T., Ohtaka, M., Nakanishi, M., Sugihara, E., Sato, T.A., Hayashi, Y., Fukuda, A. and Hisatake, K.
Stem Cells 40
(4): 397-410.
29 April 2022
Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M., Dimitriou, S., Stahler, A. ORCID: https://orcid.org/0000-0003-1041-0137, Hablesreiter, R., Strzelecka, P.M. ORCID: https://orcid.org/0000-0003-0226-6788, Stein, C.M. ORCID: https://orcid.org/0000-0002-9015-7671, Tilgner, M. ORCID: https://orcid.org/0000-0003-3196-6214, Saiki, R., Ogawa, S. ORCID: https://orcid.org/0000-0002-7778-5374, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Modest, D.P., Stintzing, S. ORCID: https://orcid.org/0000-0002-3297-5801, Heinemann, V. and Damm, F.
Blood 139
(10): 1593-1597.
10 March 2022
Management of malignant dysgerminoma of the ovary.
Arndt, T., Taube, E.T., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Rothe, K., Calaminus, G., Sehouli, J. and Pietzner, K.
European Journal of Gynaecological Oncology 43
(2): 353-362.
15 April 2022
Immunohistochemical analysis of nicotinamide phosphoribosyltransferase expression in gastric and esophageal adenocarcinoma (AEG).
Arnold, A., von Winterfeld, M., Berg, E., Hummel, M., Rau, B. ORCID: https://orcid.org/0000-0001-5820-6907, Krenzien, F. ORCID: https://orcid.org/0000-0003-0593-9917, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773
Gastrointestinal Disorders 4
(4): 333-340.
13 December 2022
Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S. ORCID: https://orcid.org/0000-0003-1830-5737, Andreani, M. ORCID: https://orcid.org/0000-0003-1426-5854, Goncalves Andrade, J., Saha, T., Sundaravinayagam, D. ORCID: https://orcid.org/0000-0003-0717-7530, Garzón, J., Zhang, W., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Hiraga, S. ORCID: https://orcid.org/0000-0002-8722-3869, Rahjouei, A. ORCID: https://orcid.org/0000-0003-3973-6333, Rosen, D.B. ORCID: https://orcid.org/0000-0002-0412-6239, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Chait, B.T., Donaldson, A.D. ORCID: https://orcid.org/0000-0001-7842-8136 and Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793
eLife 11
: e75047.
13 April 2022
Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D. ORCID: https://orcid.org/0000-0001-5948-0932, Hörtenhuber, M. ORCID: https://orcid.org/0000-0002-5599-5565, Balwierz, P.J. ORCID: https://orcid.org/0000-0002-1548-4605, Zehnder, T. ORCID: https://orcid.org/0000-0002-4127-2673, Mukarram, A.K., Nepal, C., Várnai, C. ORCID: https://orcid.org/0000-0003-0048-9507, Hadzhiev, Y. ORCID: https://orcid.org/0000-0002-1134-4904, Jimenez-Gonzalez, A. ORCID: https://orcid.org/0000-0001-7702-6135, Li, N. ORCID: https://orcid.org/0000-0002-8919-2357, Wragg, J., D'Orazio, F.M., Relic, D. ORCID: https://orcid.org/0000-0001-6237-3345, Pachkov, M. ORCID: https://orcid.org/0000-0001-7616-6435, Díaz, N. ORCID: https://orcid.org/0000-0002-0319-3448, Hernández-Rodríguez, B. ORCID: https://orcid.org/0000-0002-5118-8715, Chen, Z. ORCID: https://orcid.org/0000-0002-8376-7367, Stoiber, M., Dong, M. ORCID: https://orcid.org/0000-0003-4084-3099, Stevens, I. ORCID: https://orcid.org/0000-0003-3823-1499, Ross, S.E., Eagle, A., Martin, R., Obasaju, O. ORCID: https://orcid.org/0000-0001-5952-3103, Rastegar, S. ORCID: https://orcid.org/0000-0003-4411-5646, McGarvey, A.C. ORCID: https://orcid.org/0000-0003-3838-1139, Kopp, W. ORCID: https://orcid.org/0000-0003-0376-0032, Chambers, E. ORCID: https://orcid.org/0000-0003-1252-8059, Wang, D. ORCID: https://orcid.org/0000-0003-0068-1005, Kim, H.R., Acemel, R.D. ORCID: https://orcid.org/0000-0003-4120-0140, Naranjo, S. ORCID: https://orcid.org/0000-0002-4529-3332, Łapiński, M. ORCID: https://orcid.org/0000-0003-4892-976X, Chong, V. ORCID: https://orcid.org/0000-0002-2547-3694, Mathavan, S., Peers, B., Sauka-Spengler, T. ORCID: https://orcid.org/0000-0001-9289-0263, Vingron, M. ORCID: https://orcid.org/0000-0002-1765-4241, Carninci, P. ORCID: https://orcid.org/0000-0001-7202-7243, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340, Burgess, S.M. ORCID: https://orcid.org/0000-0003-1147-0596, Winata, C. ORCID: https://orcid.org/0000-0002-7718-5248, van Eeden, F. ORCID: https://orcid.org/0000-0003-3483-8269, Vaquerizas, J.M. ORCID: https://orcid.org/0000-0002-6583-6541, Gómez-Skarmeta, J.L. ORCID: https://orcid.org/0000-0001-5125-4332, Onichtchouk, D. ORCID: https://orcid.org/0000-0001-6497-1445, Brown, B.J. ORCID: https://orcid.org/0000-0002-5898-5848, Bogdanovic, O. ORCID: https://orcid.org/0000-0001-5680-0056, van Nimwegen, E. ORCID: https://orcid.org/0000-0001-6338-1312, Westerfield, M. ORCID: https://orcid.org/0000-0003-1187-7839, Wardle, F.C ORCID: https://orcid.org/0000-0001-5444-1889, Daub, C.O. ORCID: https://orcid.org/0000-0002-3295-8729, Lenhard, B. ORCID: https://orcid.org/0000-0002-1114-1509 and Müller, F. ORCID: https://orcid.org/0000-0002-0996-774X
Nature Genetics 54
(7): 1037-1050.
July 2022
Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A. ORCID: https://orcid.org/0000-0002-0153-2784, Malhan, D., Dumbani, M., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Relógio, A. ORCID: https://orcid.org/0000-0002-9165-2439
Cancers 14
(14): 3458.
16 July 2022
State-of-the-art analytical methods of viral infections in human lung organoids.
Baumgardt, M. ORCID: https://orcid.org/0000-0003-2077-3716, Hülsemann, M., Löwa, A. ORCID: https://orcid.org/0000-0002-5551-731X, Fatykhova, D., Hoffmann, K., Kessler, M., Mieth, M., Hellwig, K., Frey, D., Langenhagen, A., Voss, A., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Dökel, S., Gruber, A.D., Tölch, U., Hippenstiel, S., Hocke, A.C. and Hönzke, K. ORCID: https://orcid.org/0000-0003-0826-2825
PLoS ONE 17
(12): e0276115.
20 December 2022
Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics.
Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Razzaque, Y.S., Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Fürst, S., Vechiatto, C., Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Frontiers in Molecular Biosciences 9
: 859787.
12 August 2022
Claudin-targeted suicide gene therapy for claudin-overexpressing tumor cells by using modified clostridium perfringens enterotoxin (CPE).
Beier, L.S., Piontek, J., Piontek, A., Protze, J., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648 and Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231
Methods in Molecular Biology 2521
(3): 173-188.
23 June 2022
Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Berlak, M. ORCID: https://orcid.org/0000-0003-4437-3477, Tucker, E., Dorel, M. ORCID: https://orcid.org/0000-0002-1663-2075, Winkler, A., McGearey, A., Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, da Costa, B.M., Barker, K., Fyle, E., Calton, E., Eising, S., Ober, K., Hughes, D., Koutroumanidou, E., Carter, P., Stankunaite, R., Proszek, P., Jain, N., Rosswog, C., Dorado-Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Molenaar, J.J., Hubank, M., Barone, G., Anderson, J., Lang, P., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Künkele, A., Fischer, M., Eggert, A., Kloft, C., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Boettcher, M., Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Chesler, L. and Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201
Molecular Cancer 21
(1): 126.
10 June 2022
Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R., Dickinson, M., Purtill, D., Barba, P., Santoro, A., Hamad, N., Kato, K., Sureda, A., Greil, R., Thieblemont, C., Morschhauser, F., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Flinn, I., Rabitsch, W., Kwong, Y.L., Kersten, M.J, Minnema, M.C., Holte, H., Chan, E.H.L., Martinez-Lopez, J., Müller, A.M.S., Maziarz, R.T., McGuirk, J.P., Bachy, E., Le Gouill, S., Dreyling, M., Harigae, H., Bond, D., Andreadis, C., McSweeney, P., Kharfan-Dabaja, M., Newsome, S., Degtyarev, E., Awasthi, R., Del Corral, C., Andreola, G., Masood, A., Schuster, S.J., Jäger, U., Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386
(7): 629-639.
17 February 2022
Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T. ORCID: https://orcid.org/0000-0003-0843-2716, Funck, K. ORCID: https://orcid.org/0000-0001-6478-5562, Wollweber, F., Lisicki, E. ORCID: https://orcid.org/0000-0001-5012-8377, von der Malsburg, K., von der Malsburg, A., Laborenz, J., Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Hessenberger, M. ORCID: https://orcid.org/0000-0003-3021-1100, Jungbluth, S., Bernert, C., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Riedel, D., Lilie, H., Jakobs, S., van der Laan, M. and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Science Advances 8
(35): eabo4946.
2 September 2022
SLM2 is a novel cardiac splicing factor involved in heart failure due to dilated cardiomyopathy.
Boeckel, J.N. ORCID: https://orcid.org/0000-0002-7438-3089, Möbius-Winkler, M. ORCID: https://orcid.org/0000-0002-4400-3508, Müller, M. ORCID: https://orcid.org/0000-0002-8519-0661, Rebs, S. ORCID: https://orcid.org/0000-0002-9504-0261, Eger, N. ORCID: https://orcid.org/0000-0002-9488-4083, Schoppe, L. ORCID: https://orcid.org/0000-0003-0047-8760, Tappu, R. ORCID: https://orcid.org/0000-0003-0902-7114, Kokot, K.E. ORCID: https://orcid.org/0000-0002-8130-4289, Kneuer, J.M. ORCID: https://orcid.org/0000-0003-0273-3614, Gaul, S. ORCID: https://orcid.org/0000-0003-4780-1844, Bordalo, D.M., Lai, A. ORCID: https://orcid.org/0000-0003-0916-9227, Haas, J. ORCID: https://orcid.org/0000-0002-8040-8289, Ghanbari, M. ORCID: https://orcid.org/0000-0002-6015-2968, Drewe-Boss, P. ORCID: https://orcid.org/0000-0002-5459-9771, Liss, M. ORCID: https://orcid.org/0000-0002-0585-7850, Katus, H.A., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172, Laufs, U. ORCID: https://orcid.org/0000-0003-2620-9323, Streckfuss-Bömeke, K. ORCID: https://orcid.org/0000-0001-5137-7228 and Meder, B. ORCID: https://orcid.org/0000-0003-0741-2633
Genomics Proteomics & Bioinformatics 20
(1): 129-146.
February 2022
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska, R., Mikecin, A.M., Kaschutnig, P., Fawaz, M., Büchler-Schäff, M., Le, D., Ganuza, M., Vollmer, A., Paffenholz, S.V., Asada, N., Rodriguez-Correa, E., Frauhammer, F., Buettner, F., Ball, M., Knoch, J., Stäble, S., Walter, D., Petri, A., Carreño-Gonzalez, M.J., Wagner, V., Brors, B., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Lipka, D.B., Essers, M.A.G., Weru, V., Holland-Letz, T., Mallm, J.P., Rippe, K., Krämer, S., Schlesner, M., McKinney Freeman, S., Florian, M.C., King, K.Y., Frenette, P.S., Rieger, M.A. and Milsom, M.D.
Cell Stem Cell 29
(8): 1273-1284.
4 August 2022
Genotype and intensive pretreatment influence outcome of acute myeloid leukemia patients treated with venetoclax in combination with hypomethylating agents or low-dose cytarabine: "real world" data from germany.
Braitsch, K., Schmalbrock, L.K. ORCID: https://orcid.org/0000-0002-6080-6175, Jung, P., Bumeder, I., Kiewe, P., Hecker, J.S., Verbeek, M., Westermann, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bassermann, F., Krönke, J., Götze, K.S. and Rieger, K.
HemaSphere 6
(9): e759.
September 2022
Conditioning with fludarabine and treosulfan compared to FLAMSA-RIC in allogeneic stem cell transplantation for myeloid malignancies: a retrospective single-center analysis.
Braitsch, K. ORCID: https://orcid.org/0000-0003-4028-5357, Schwarz, A., Koch, K., Hubbuch, M., Menzel, H., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Götze, K.S., Bassermann, F., Herhaus, P. and Verbeek, M.
Annals of Hematology 101
(6): 1311-1319.
June 2022
Relapse of NPM1-mutated AML with extramedullary manifestation 17 years after allogeneic hematopoietic stem cell transplantation.
Braune, J. ORCID: https://orcid.org/0000-0003-2026-2641, Rieger, K., Blau, O. ORCID: https://orcid.org/0000-0002-4304-5079, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Krönke, J.
Case Reports in Hematology 2022
: 3317936.
28 December 2022
TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck, F. ORCID: https://orcid.org/0000-0002-0026-3658, Fischer, B., Witt, M., Muschhammer, J., Oelrich, J., da Costa Avelar, P.H. ORCID: https://orcid.org/0000-0002-0347-7002, Tsoka, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Seubert, E., Smit, D.J. ORCID: https://orcid.org/0000-0002-3190-9511, Bokemeyer, C., Ackermann, C., Wellbrock, J., Haag, F. and Fiedler, W.
Journal for ImmunoTherapy of Cancer 10
(12): e004794.
22 December 2022
Optimization of synthetic molecular reporters for a mesenchymal glioblastoma transcriptional program by integer programming.
Breitenbach, T., Schmitt, M.J. ORCID: https://orcid.org/0000-0001-8296-5858 and Dandekar, T.
Bioinformatics 38
(17): 4162-4171.
1 September 2022
Autophagy limits inflammatory gene expression through targeting of nuclear p65/RelA by LC3 and p62 for lysosomal degradation.
Brischetto, C. ORCID: https://orcid.org/0000-0001-9167-3291, Mucka, P. ORCID: https://orcid.org/0000-0003-2125-0634, Kaergel, E. and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
bioRxiv
: 2022.11.02.514846.
2 November 2022
Taking out the trash: How misfolded proteins are removed from the endoplasmic reticulum.
Brodsky, J.L. ORCID: https://orcid.org/0000-0002-6984-8486, Engelman, D.M. ORCID: https://orcid.org/0000-0002-6312-4583, Hendershot, L.M. ORCID: https://orcid.org/0000-0002-5473-0274, Piana-Agostinetti, S. and Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202
Faculty Reviews 11
: 29.
5 October 2022
Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation.
Brunner, A.D. ORCID: https://orcid.org/0000-0002-2733-7899, Thielert, M., Vasilopoulou, C., Ammar, C. ORCID: https://orcid.org/0000-0003-4310-6908, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Mund, A. ORCID: https://orcid.org/0000-0002-7843-5341, Hoerning, O.B., Bache, N., Apalategui, A., Lubeck, M., Richter, S. ORCID: https://orcid.org/0000-0001-6101-2783, Fischer, D.S. ORCID: https://orcid.org/0000-0002-1293-7656, Raether, O., Park, M.A., Meier, F. ORCID: https://orcid.org/0000-0003-4729-175X, Theis, F.J. ORCID: https://orcid.org/0000-0002-2419-1943 and Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799
Molecular Systems Biology 18
(3): e10798.
1 March 2022
CEBPA mutations in AML: site matters.
Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood 139
(1): 6-7.
6 January 2022
Generation of redirected engineered human chimeric antigen receptor (CAR) T cells.
Bunse, M. ORCID: https://orcid.org/0000-0002-7554-2520 and Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893
Methods in Molecular Biology 2521
(3): 67-83.
23 June 2022
Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA interdisciplinary expert consensus.
Buske, C., Dreyling, M., Alvarez-Larrán, A., Apperley, J., Arcaini, L., Besson, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Corradini, P., Della Porta, M.G., Dimopoulos, M., D’Sa, S., Eich, H.T., Foà, R., Ghia, P., Gomes da Silva, M., Gribben, J., Hajek, R., Harrison, C., Heuser, M., Kiesewetter, B., Kiladjian, J.J., Kröger, N., Moreau, P., Passweg, J.R., Peyvandi, F., Rea, D., Ribera, J.M., Robak, T., San-Miguel, J.F., Santini, V., Sanz, G., Sonneveld, P., von Lilienfeld-Toal, M., Wendtner, C., Pentheroudakis, G. and Passamonti, F.
ESMO Open 7
(2): 100403.
April 2022
Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I., Jaeschke, L. ORCID: https://orcid.org/0000-0002-5661-228X, Nimptsch, K. ORCID: https://orcid.org/0000-0001-7877-205X, Janke, J. ORCID: https://orcid.org/0000-0003-0113-4118, Herrmann, P., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Kielstein, H., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
International Journal of Oncology 60
(2): 17.
February 2022
B cells are addicted to immunoglobulin production in the ER.
Caganova, M. ORCID: https://orcid.org/0000-0002-4576-6574, Taskiran, H., Zong, Y., Zach, A., Kabrani, E. ORCID: https://orcid.org/0000-0003-0834-9912, Schmidt, K., Goffing, P., Jellusova, J. and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
bioRxiv
: 2022.03.11.483940.
14 March 2022
Building a Healthcare Alliance for Resourceful Medicine Offensive Against Neoplasms in hematologY added value framework for hematologic malignancies: a comparative analysis of existing tools.
Cerisoli, F., Ali, F., Bereczky, T., Bolaños, N., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Dhanasiri, S., Gallagher, J., Pérez, S.G., Geissler, J., Guillevic, Y., Harrison, K., Naoum, A., Portulano, C., Rodríguez Vicente, A.E., Schulze-Rath, R., Gómez, G.Y., Sanz, G. and Hernández Rivas, J.M.
Value in Health 25
(10): 1760-1767.
October 2022
Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F., Hablesreiter, R., Hoyer, K., Hennch, C. ORCID: https://orcid.org/0000-0003-4104-5531, Maluck-Böttcher, A., Segler, A., Madadi, A., Frick, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Briest, F. ORCID: https://orcid.org/0000-0001-5969-9467 and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
Leukemia 36
(4): 1102-1110.
April 2022
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki, F. ORCID: https://orcid.org/0000-0003-3043-0653, Bjordahl, R., Goodridge, J.P., Mahmood, S., Gaidarova, S., Abujarour, R., Davis, Z.B., Merino, A. ORCID: https://orcid.org/0000-0003-4433-0127, Tuininga, K., Wang, H., Kumar, A., Groff, B., Witty, A., Bonello, G., Huffman, J., Dailey, T., Lee, T.T., Malmberg, K.J. ORCID: https://orcid.org/0000-0002-8718-9373, Walcheck, B., Höpken, U. ORCID: https://orcid.org/0000-0002-0776-4893, Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950, Valamehr, B. ORCID: https://orcid.org/0000-0002-5917-3585 and Miller, J.S. ORCID: https://orcid.org/0000-0002-0339-4944
Nature Communications 13
(1): 7341.
29 November 2022
Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E. ORCID: https://orcid.org/0000-0002-5601-1695, Althoff, S., Ruß, J., Rosnev, S. ORCID: https://orcid.org/0000-0003-0256-7038, Butze, M., Pühl, M., Frentsch, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
International Journal of Molecular Sciences 23
(6): 3207.
16 March 2022
Hemostatic management in an infant with neuroblastoma and severe hemophilia B with extended half-life recombinant factor IX fusion protein.
Cuntz, F., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Schulte, J.H., Nimtz-Talaska, A., Eggert, A. and Holzhauer, S.
Journal of Pediatric Hematology Oncology 44
(1): e246-e249.
1 January 2022
Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Monks, A., Harris, E.D., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Osterland, M. ORCID: https://orcid.org/0000-0001-9133-9322, Khaireddine, F., Herrmann, P., Kemmner, W. ORCID: https://orcid.org/0000-0002-1494-7225, Burock, S., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Shoemaker, R.H. and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cancers 14
(1): 37.
2022
Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group.
Damaschin, C., Goergen, H., Kreissl, S., Plütschow, A., Breywisch, F., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Meissner, J., Sökler, M., Topp, M.S., Vucinic, V., Zimmermann, A., von Tresckow, B., Fuchs, M., Engert, A., Borchmann, P. and Eichenauer, D.A. ORCID: https://orcid.org/0000-0002-1927-3514
Leukemia 36
(2): 580-582.
February 2022
SPFH protein cage - one ring to rule them all.
Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352
Cell Research 32
(2): 117-118.
February 2022
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Demel, U.M. ORCID: https://orcid.org/0000-0002-6480-4185, Böger, M. ORCID: https://orcid.org/0000-0001-9301-5022, Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Grunert, C. ORCID: https://orcid.org/0000-0001-8376-8629, Zhang, L., Hotz, P.W., Gottschlich, A., Köse, H., Isaakidis, K., Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Rohleder, E., Wagner, K., Dönig, J., Igl, V., Brzezicha, B., Baumgartner, F. ORCID: https://orcid.org/0000-0003-0768-1956, Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Löber, J., Chapuy, B., Weidinger, C., Kobold, S., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Busse, A.B. ORCID: https://orcid.org/0000-0002-3470-6947, Müller, S., Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611 and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Journal of Clinical Investigation 132
(9): e152383.
2 May 2022
A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo.
Demel, U.M. ORCID: https://orcid.org/0000-0002-6480-4185, Lutz, R., Sujer, S., Demerdash, Y., Sood, S., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Kuck, A., Werner, P., Blaszkiewicz, S., Uckelmann, H.J., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051 and Essers, M.
Blood Advances 6
(11): 3513-3528.
10 June 2022
Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Frick, M., Kase, J., Hoffmann, J., Trenker, C., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bogner, C., Hüttmann, A., Dürig, J., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Marks, R., Krohn, U., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Leukemia & Lymphoma 63
(1): 84-92.
January 2022
A deep dive into the circulating ctDNA cosmos to vanquish neuroblastoma.
Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997 and Lodrini, M. ORCID: https://orcid.org/0000-0003-4434-529X
Cancer Discovery 12
(12): 2727-2729.
2 December 2022
Personalisierte Medizin in der Kinderonkologie: Wo stehen wir heute?
Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201 and Eggert, A.
TumorDiagnostik & Therapie 43
(01): 29-44.
February 2022
Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
Dieckmann, S., Strohmeyer, A., Willershäuser, M., Maurer, S.F., Wurst, W., Marschall, S., Hrabě de Angelis, M., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Worthmann, A., Fuh, M.M., Heeren, J., Köhler, N., Pauling, J.K. and Klingenspor, M.
American Journal of Physiology Endocrinology and Metabolism 322
(2): E85-E100.
February 2022
Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S. ORCID: https://orcid.org/0000-0002-0753-9266, Company, C. ORCID: https://orcid.org/0000-0002-7975-0642, Song, K. ORCID: https://orcid.org/0000-0001-6216-8157, Lowenstein, E.D. ORCID: https://orcid.org/0000-0003-3755-0818, Riedel, L. ORCID: https://orcid.org/0000-0003-0389-8410, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251 and Zampieri, N. ORCID: https://orcid.org/0000-0002-2228-9453
Nature Communications 13
(1): 6867.
11 November 2022
NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
Doffo, J., Bamopoulos, S.A. ORCID: https://orcid.org/0000-0002-5997-7735, Köse, H. ORCID: https://orcid.org/0000-0003-4307-5654, Orben, F. ORCID: https://orcid.org/0000-0002-2196-8702, Zang, C., Pons, M., den Dekker, A.T., Brouwer, R.W.W., Baluapuri, A. ORCID: https://orcid.org/0000-0002-3723-7891, Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Reichert, M., Illendula, A., Krämer, O.H., Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Wolf, E. ORCID: https://orcid.org/0000-0002-5299-6335, van IJcken, W.F.J. ORCID: https://orcid.org/0000-0002-0421-8301, Esposito, I., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Schneider, G. ORCID: https://orcid.org/0000-0003-1840-4508 and Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872
Proceedings of the National Academy of Sciences of the United States of America 119
(9): e2105691119.
1 March 2022
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Pusch, F. ORCID: https://orcid.org/0000-0002-7152-080X, Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, von Stebut, J. ORCID: https://orcid.org/0000-0001-9811-445X, Ibáñez, G., Guillan, K., Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Rolff, J., Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Meyer-Liesener, S., Timme, N., Bardinet, V. ORCID: https://orcid.org/0000-0002-9583-7043, Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, MacArthur, I.C. ORCID: https://orcid.org/0000-0003-1718-1349, Chen, C.Y. ORCID: https://orcid.org/0000-0002-1579-024X, Schulz, J., Wengner, A.M. ORCID: https://orcid.org/0009-0009-5772-1945, Furth, C., Lala, B., Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Seifert, G., Hundsoerfer, P., Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Lissat, A., Dubois, F. ORCID: https://orcid.org/0000-0002-7654-6208, Horst, D., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, You, D., Dela Cruz, F., Kung, A.L. ORCID: https://orcid.org/0000-0002-9091-488X, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793, Scheer, M., Ortiz, M.V. and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Nature Communications 13
(1): 4297.
25 July 2022
Simultaneous imaging and flow-cytometry-based detection of multiple fluorescent senescence markers in therapy-induced senescent cancer cells.
Dovjak, E., Mairhofer, M., Wöß, C., Qi, J., Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Yu, Y.
Journal of Visualized Experiments
(185): e63973.
12 July 2022
Deep learning for prediction of population health costs.
Drewe-Boss, P. ORCID: https://orcid.org/0000-0002-5459-9771, Enders, D., Walker, J. and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
BMC Medical Informatics and Decision Making 22
(1): 32.
3 February 2022
Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.
Dzamukova, M. ORCID: https://orcid.org/0000-0002-2389-3222, Brunner, T.M., Miotla-Zarebska, J., Heinrich, F. ORCID: https://orcid.org/0000-0001-6097-5422, Brylka, L. ORCID: https://orcid.org/0000-0003-4734-9966, Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Kusumbe, A. ORCID: https://orcid.org/0000-0002-1911-5495, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Schinke, T. ORCID: https://orcid.org/0000-0002-8576-0177, Vincent, T.L.. and Löhning, M. ORCID: https://orcid.org/0000-0001-6382-7281
Nature Communications 13
(1): 3059.
1 June 2022
Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Wulf, G.G., Salih, H.R., Lübbert, M., Kühn, M., Schroeder, T., Salwender, H., Götze, K.S., Westermann, J., Fransecky, L., Mayer, K., Hertenstein, B., Ringhoffer, M., Tischler, H.J., Machherndl-Spandl, S., Schrade, A., Paschka, P., Gaidzik, V.I., Theis, F., Thol, F.R., Heuser, M., Schlenk, R.F., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Saadati, M., Benner, A., Larson, R.A., Stone, R.M., Döhner, K. and Ganser, A.
Blood Advances 6
(18): 5345-5355.
27 September 2022
C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages.
Dörr, D. ORCID: https://orcid.org/0000-0001-8575-7560, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Weiner, J.M. ORCID: https://orcid.org/0000-0003-1438-7819, Zimmermann, K., Anania, C. ORCID: https://orcid.org/0000-0003-1549-4157, Wagner, L.K., Lyras, E.M. ORCID: https://orcid.org/0000-0003-3269-0854, Sapozhnikova, V., Lara-Astiaso, D. ORCID: https://orcid.org/0000-0001-8686-4675, Prósper, F. ORCID: https://orcid.org/0000-0001-6115-8790, Lang, R., Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X and Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427
Science Immunology 7
(75): eabj0140.
September 2022
Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T(H)2-biased immunization.
Ebenig, A., Muraleedharan, S., Kazmierski, J., Todt, D., Auste, A., Anzaghe, M., Gömer, A., Postmus, D., Gogesch, P., Niles, M., Plesker, R., Miskey, C. ORCID: https://orcid.org/0000-0002-7566-9556, Gellhorn Serra, M., Breithaupt, A., Hörner, C., Kruip, C., Ehmann, R., Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658, Waibler, Z., Pfaender, S., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Kupke, A., Nouailles, G., Goffinet, C., Brown, R.J.P and Mühlebach, M.D.
Cell Reports 40
(7): 111214.
16 August 2022
TCR and CAR engineering of primary human T cells.
Edes, I., Clauss, J. ORCID: https://orcid.org/0000-0001-6783-1536, Stahn, R., Sada Japp, A. ORCID: https://orcid.org/0000-0001-8106-8987 and Lorenz, F.K.M. ORCID: https://orcid.org/0000-0001-7826-0839
Methods in Molecular Biology 2521
(3): 85-93.
23 June 2022
Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL - long-term follow-up from the prospective ALL-SCT 2003 trial.
Eichinger, A. ORCID: https://orcid.org/0000-0002-2256-6633, Poetschger, U., Glogova, E., Bader, P. ORCID: https://orcid.org/0000-0003-4554-0265, Basu, O., Beier, R., Burkhardt, B. ORCID: https://orcid.org/0000-0002-1151-829X, Classen, C.F., Claviez, A. ORCID: https://orcid.org/0000-0001-7064-8556, Corbacioglu, S., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Greil, J., Gruhn, B. ORCID: https://orcid.org/0000-0003-1862-0075, Güngör, T. ORCID: https://orcid.org/0000-0002-3261-1186, Kafa, K., Kühl, J.S., Lang, P. ORCID: https://orcid.org/0000-0001-7737-2142, Lange, B.S., Meisel, R. ORCID: https://orcid.org/0000-0001-5230-0628, Müller, I. ORCID: https://orcid.org/0000-0002-7477-6632, Sauer, M.G., Schlegel, P.G., Schulz, A. ORCID: https://orcid.org/0000-0002-7798-7996, Stachel, D., Strahm, B. ORCID: https://orcid.org/0000-0002-6086-130X, Wawer, A., Peters, C. ORCID: https://orcid.org/0000-0003-0369-8515 and Albert, M.H. ORCID: https://orcid.org/0000-0001-9143-3263
Leukemia 36
(11): 2567-2576.
November 2022
An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils.
Ellson, C.D., Goretti Riça, I., Kim, J.S., Huang, Y.M.M., Lim, D., Mitra, T., Hsu, A., Wei, E.X., Barrett, C.D., Otterbein, L.E., Hauser, C.J., Wahl, M., Delbrück, H., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Oschkinat, H., Chang, C.E.A. and Yaffe, M.B.
Journal of Molecular Biology 434
(9): 167533.
15 May 2022
Evidence for recombinant GRP78, CALR, PDIA3 and GPI as mediators of genetic instability in human CD34+ cells.
Fabarius, A. ORCID: https://orcid.org/0000-0001-5976-2876, Samra, V., Drews, O., Mörz, H., Bierbaum, M., Darwich, A. ORCID: https://orcid.org/0000-0001-9463-9638, Weiss, C., Brendel, S., Kleiner, H., Seifarth, W., Greffrath, W., Hofmann, W.K., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Popp, H.D. ORCID: https://orcid.org/0000-0003-0090-0204
Cancers 14
(12): 2883.
11 June 2022
A cFLIP-flop switch for senolysis.
Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Cancer 3
(11): 1279-1281.
November 2022
Clonal hematopoiesis of indeterminate potential-related epigenetic age acceleration correlates with clonal hematopoiesis of indeterminate potential clone size in patients with high morbidity.
Feldkamp, J.D., Vetter, V.M., Arends, C.M., Lang, T.J.L., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Damm, F., Demuth, I. and Frick, M.
Haematologica 107
(7): 1703-1708.
July 2022
Assessing evolutionary and developmental transcriptome dynamics in homologous cell types.
Feregrino, C. ORCID: https://orcid.org/0000-0003-0300-5483 and Tschopp, P. ORCID: https://orcid.org/0000-0001-7339-3990
Developmental Dynamics 251
(9): 1472-1489.
September 2022
Long-term efficacy, safety and neurotolerability of MATRix regimen followed by autologous transplant in primary CNS lymphoma: 7-year results of the IELSG32 randomized trial.
Ferreri, A.J.M. ORCID: https://orcid.org/0000-0001-9606-6124, Cwynarski, K. ORCID: https://orcid.org/0000-0001-9936-3431, Pulczynski, E., Fox, C.P., Schorb, E., Celico, C., Falautano, M., Nonis, A., La Rosée, P. ORCID: https://orcid.org/0000-0002-6758-7809, Binder, M., Fabbri, A., Ilariucci, F., Krampera, M. ORCID: https://orcid.org/0000-0002-7280-2040, Roth, Al., Hemmaway, C., Johnson, P.W., Linton, K.M., Pukrop, T., Gørløv, J.S., Balzarotti, M., Hess, G. ORCID: https://orcid.org/0000-0002-9282-5688, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Stilgenbauer, S., Panse, J. ORCID: https://orcid.org/0000-0001-6316-3112, Tucci, A. ORCID: https://orcid.org/0000-0003-3052-7463, Orsucci, L., Pisani, F., Zanni, M., Krause, S.W. ORCID: https://orcid.org/0000-0002-5259-4651, Schmoll, H.J., Hertenstein, B., Rummel, M., Smith, J., Thurner, L., Cabras, G., Pennese, E., Ponzoni, M., Deckert, M., Politi, L.S., Finke, J. ORCID: https://orcid.org/0000-0002-1799-5927, Ferranti, A., Cozens, K., Burger, E., Ielmini, N., Cavalli, F., Zucca, E. ORCID: https://orcid.org/0000-0002-5522-6109 and Illerhaus, G.
Leukemia 36
(7): 1870-1878.
July 2022
R-spondin-YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.
Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Müllerke, S., Arnold, A., Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Berger, H., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Wizenty, J. ORCID: https://orcid.org/0000-0003-4261-0416, Horst, D. ORCID: https://orcid.org/0000-0003-4755-5743, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Journal of Clinical Investigation 132
(21): e151363.
1 November 2022
Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC.
Fiskin, E., Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Eraslan, G. ORCID: https://orcid.org/0000-0001-9579-2909, Liu, F., Ring, A.M. ORCID: https://orcid.org/0000-0003-3699-2446, Xavier, R.J. and Regev, A. ORCID: https://orcid.org/0000-0003-3293-3158
Nature Biotechnology 40
(3): 374-381.
March 2022
Differentiation of cerebral neoplasms with vessel size imaging (VSI).
Foda, A. ORCID: https://orcid.org/0000-0003-1694-1983, Kellner, E., Gunawardana, A., Gao, X., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Kufner, A., Khalil, A.A., Geran, R., Mekle, R., Fiebach, J.B. and Galinovic, I.
Clinical Neuroradiology 32
(1): 239-248.
March 2022
Dataset debt in biomedical language modeling.
Fries, J.A., Seelam, N., Altay, G., Weber, L. ORCID: https://orcid.org/0000-0002-2499-472X, Kang, M., Datta, D., Su, R., Garda, S., Wang, B., Ott, S., Samwald, M. and Kusa, W.
In: 2022 Challenges and Perspectives in Creating Large Language Models, 27 May 2022, Virtual, Dublin.
May 2022
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.
Garces de Los Fayos Alonso, I., Zujo, L., Wiest, I., Kodajova, P., Timelthaler, G., Edtmayer, S., Zrimšek, M., Kollmann, S., Giordano, C., Kothmayer, M., Neubauer, H.A., Dey, S., Schlederer, M., Schmalzbauer, B.S., Limberger, T., Probst, C., Pusch, O., Högler, S., Tangermann, S., Merkel, O., Schiefer, A.I., Kornauth, C., Prutsch, N., Zimmerman, M., Abraham, B., Anagnostopoulos, J., Quintanilla-Martinez, L., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Wolf, P., Stoiber, D., Staber, P.B., Egger, G., Klapper, W., Woessmann, W., Look, T.A., Gunning, P., Turner, S.D., Moriggl, R., Lagger, S. and Kenner, L.
Molecular Cancer 21
(1): 172.
31 August 2022
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.
Garipler, G., Lu, C., Morrissey, Al. ORCID: https://orcid.org/0000-0003-0480-0112, Lopez-Zepeda, L.S. ORCID: https://orcid.org/0000-0001-9764-0984, Pei, Y. ORCID: https://orcid.org/0000-0002-7518-3935, Vidal, S.E., Zen Petisco Fiore, A.P., Aydin, B., Stadtfeld, M., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Mahony, S. ORCID: https://orcid.org/0000-0002-2641-1807, Sanjana, N.E. ORCID: https://orcid.org/0000-0002-1504-0027 and Mazzoni, E.O. ORCID: https://orcid.org/0000-0001-8994-681X
Cell Reports 38
(11): 110524.
15 March 2022
SARS-CoV-2-specific antibody (Ab) levels and the kinetic of ab decline determine Ab persistence over 1 year.
Garner-Spitzer, E., Wagner, A., Kundi, M., Stockinger, H., Ohradanova-Repic, A., Gebetsberger, L., Schoetta, A.M., Gudipati, V., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Kunert, R., Mayrhofer, P., Kreil, T.R., Farcet, M.R., Hoeltl, E. and Wiedermann, U.
Frontiers in Medicine 9
: 822316.
15 February 2022
IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis.
Garnier, L. ORCID: https://orcid.org/0000-0003-4006-5741, Pick, R. ORCID: https://orcid.org/0000-0001-9785-8481, Montorfani, J. ORCID: https://orcid.org/0000-0001-9028-1595, Sun, M., Brighouse, D., Liaudet, N. ORCID: https://orcid.org/0000-0002-0749-5857, Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Page, N., Bernier-Latamani, J., Tran, N.L., Petrova, T.V. ORCID: https://orcid.org/0000-0002-0563-6521, Merkler, D. ORCID: https://orcid.org/0000-0002-0247-2007, Scheiermann, C. ORCID: https://orcid.org/0000-0002-9212-0995 and Hugues, S. ORCID: https://orcid.org/0000-0002-1031-5909
Science Advances 8
(23): eabl5162.
8 June 2022
Wie Kochsalz Mitochondrien beeinflusst.
Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312
BIOspektrum 28
(4): 387-389.
June 2022
Bruton's tyrosine kinase inhibitors in multiple sclerosis: pioneering the path towards treatment of progression?
Geladaris, A., Torke, S. ORCID: https://orcid.org/0000-0002-1029-3623 and Weber, M.S.
CNS drugs 36
(10): 1019-1030.
October 2022
Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg, P., Astaburuaga-García, R., Bonaguro, L., Brumhard, S., Michalick, L., Lippert, L.J., Kostevc, T., Gäbel, C., Schneider, M., Streitz, M., Demichev, V., Gemünd, I., Barone, M., Tober-Lau, P., Helbig, E.T., Hillus, D., Petrov, L., Stein, J., Dey, H.P., Paclik, D., Iwert, C., Mülleder, M., Aulakh, S.K., Djudjaj, S., Bülow, R.D., Mei, H.E., Schulz, A.R., Thiel, A., Hippenstiel, S., Saliba, A.E., Eils, R., Lehmann, I., Mall, M.A., Stricker, S., Röhmel, J., Corman, V.M., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, von Stillfried, S., Boor, P., Demir, M., Wesselmann, H., Suttorp, N., Uhrig, A., Müller-Redetzky, H., Nattermann, J., Kuebler, W.M., Meisel, C., Ralser, M., Schultze, J.L., Aschenbrenner, A.C., Thibeault, C., Kurth, F., Sander, L.E., Blüthgen, N. and Sawitzki, B.
Cell 185
(3): 493-512.
3 February 2022
An unusual aspartic acid cluster in the reovirus attachment fiber s1 mediates stability at low pH and preserves trimeric organization.
Glorani, G. ORCID: https://orcid.org/0000-0002-4191-1092, Ruwolt, M., Holton, N., Loll, B. ORCID: https://orcid.org/0000-0001-7928-4488 and Neu, U. ORCID: https://orcid.org/0000-0001-6852-0879
Journal of Virology 96
(8): e0033122.
April 2022
Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O., Zincke, F., Eckert, A., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Preissner, S., Liebeskind, J.M., Gunkel, N., Putzker, K., Lewis, J., Preissner, S., Kortüm, B. ORCID: https://orcid.org/0000-0003-3734-6665, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Mura, K., Bourne, P.E., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Preissner, R. ORCID: https://orcid.org/0000-0002-2407-1087
Clinical and Translational Medicine 12
(2): e726.
20 February 2022
The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S., Cabantog, A., MacPhee, L., Im, J., Ruess, C., Demir, B., Sperb, N., Rücker, F.G., Döhner, K., Herold, T., Pollack, J.R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rouhi, A. and Kuchenbauer, F.
Haematologica 107
(8): 1758-1772.
August 2022
Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.
Grinat, J. ORCID: https://orcid.org/0000-0003-0152-4941, Kosel, F., Goveas, N. ORCID: https://orcid.org/0000-0002-2531-5514, Kranz, A. ORCID: https://orcid.org/0000-0002-7481-0220, Alexopoulou, D. ORCID: https://orcid.org/0000-0002-3715-1756, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Stewart, A.F. and Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X
Life Science Alliance 5
(4): e202101187.
April 2022
Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside?
Guedan, S., Luu, M., Ammar, D., Barbao, P., Bonini, C., Bousso, P., Buchholz, C.J., Casucci, M., De Angelis, B. ORCID: https://orcid.org/0000-0002-7938-737X, Donnadieu, E. ORCID: https://orcid.org/0000-0002-4985-7254, Espie, D., Greco, B., Groen, R., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Kantari-Mimoun, C., Laugel, B., Mantock, M., Markman, J.L., Morris, E., Quintarelli, C. ORCID: https://orcid.org/0000-0002-4343-9705, Rade, M., Reiche, K., Rodriguez-Garcia, A., Rodriguez-Madoz, J.R., Ruggiero, E., Themeli, M., Hudecek, M. and Marchiq, I.
Journal for ImmunoTherapy of Cancer 10
(5): e003487.
May 2022
Mechanosurveillance: Tiptoeing T cells.
Göhring, J., Schrangl, L., Schütz, G.J. and Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198
Frontiers in Immunology 13
: 886328.
26 May 2022
MACC1-dependent antitumor effect of curcumin in colorectal cancer.
Güllü, N., Smith, J., Herrmann, P. and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Nutrients 14
(22): 4792.
12 November 2022
A molecularly characterized preclinical platform of subcutaneous renal cell carcinoma (RCC) patient-derived xenograft models to evaluate novel treatment strategies.
Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Becker, M., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Flechsig, S., Schaeffeler, E., Büttner, F.A., Schmees, C., Bohnert, R., Bedke, J., Schwab, M., Wendler, J.J., Schostak, M., Jandrig, B., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Hoffmann, J. ORCID: https://orcid.org/0000-0003-3880-1658
Frontiers in Oncology 12
: 889789.
21 June 2022
miR-142 favors naïve B cell residence in peripheral lymph nodes.
Hagen, M., Chakraborty, T., Olson, W.J., Heitz, M., Hermann-Kleiter, N., Kimpel, J., Jenewein, B., Pertoll, J., Labi, V. ORCID: https://orcid.org/0000-0001-7538-1520, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Derudder, E. ORCID: https://orcid.org/0000-0003-1421-4045
Frontiers in Immunology 13
: 847415.
10 November 2022
Refining AML treatment: the role of genetics in response and resistance evaluation to new agents.
Halik, A., Arends, C.M. ORCID: https://orcid.org/0000-0003-4417-4750, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Damm, F. and Frick, M.
Cancers 14
(7): 1689.
26 March 2022
A critical period of translational control during brain development at codon resolution.
Harnett, D. ORCID: https://orcid.org/0000-0002-9190-128X, Ambrozkiewicz, M.C. ORCID: https://orcid.org/0000-0001-5225-5230, Zinnall, U. ORCID: https://orcid.org/0000-0002-0782-7751, Rusanova, A., Borisova, E., Drescher, A.N., Couce-Iglesias, M., Villamil, G. ORCID: https://orcid.org/0000-0001-6701-9505, Dannenberg, R., Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Münster-Wandowski, A., Fauler, B., Mielke, T., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Spahn, C.M.T., Tarabykin, V., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Kraushar, M.L.
Nature Structural & Molecular Biology 29
(12): 1277-1290.
December 2022
Widely applicable, extended flow cytometric stem cell enumeration panel for quality control of advanced cellular products.
Haussmann, K., Streitz, M., Takvorian, A., Grund, J., Skenderi, Z., Tietze-Bürger, C., Movassaghi, K., Künkele, A., Blum, A. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Scientific Reports 12
(1): 17995.
26 October 2022
Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia.
Hegazy, A.N. ORCID: https://orcid.org/0000-0002-2946-8251, Krönke, J., Angermair, S., Schwartz, S., Weidinger, C., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Treskatsch, S., Siegmund, B. and Schneider, T.
BMC Infectious Diseases 22
(1): 537.
13 June 2022
Shedding light on ecDNA behavior using CRISPR-based live-cell imaging.
Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Cancer Discovery 12
(2): 293-295.
9 February 2022
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca, P., Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Schnell, A., Uckelmann, H.J., Bollhagen, A., Mahmoud, M.A.A., Landua, S.L., van der Salm, E., Trautmann, C., Raffel, S., Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Lutz, R., Ghosh, M., Renders, S., Correia, N., Donato, E., Dixon, K.O., Hirche, C., Andresen, C., Robens, Cl., Werner, P.S., Boch, T., Eisel, D., Osen, W., Pilz, F., Przybylla, A., Klein, C., Buchholz, F., Milsom, M.D., Essers, M.A.G., Eichmüller, S.B., Hofmann, W.K., Nowak, D., Hübschmann, D., Hundemer, M., Thiede, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Müller-Tidow, C., Armstrong, S.A., Trumpp, A., Kuchroo, V.K. and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Cell Stem Cell 29
(5): 760-775.
5 May 2022
A phase II trial to evaluate the combination of pixantrone and obinutuzumab for patients with relapsed aggressive lymphoma: Final results of the prospective, multicentre GOAL trial.
Hess, G. ORCID: https://orcid.org/0000-0002-9282-5688, Hüttmann, A. ORCID: https://orcid.org/0000-0003-2230-3873, Witzens-Harig, M., Dreyling, M.H., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Marks, R., Ernst, T., Pott, C., Viardot, A., Frontzek, F., Trautmann, M., Ruckes, C., Deuster, O., Rosenwald, A., Theobald, M. and Lenz, G.
British Journal of Haematology 198
(3): 482-491.
1 April 2022
Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors.
Heynen, G.J.J.E. ORCID: https://orcid.org/0000-0001-7721-5710, Lisek, K. ORCID: https://orcid.org/0000-0002-2406-8830, Vogel, R., Wulf-Goldenberg, A., Alcaniz, J., Montaudon, E., Marangoni, E. and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Breast Cancer Research 24
(1): 23.
1 April 2022
Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury.
Hinze, C. ORCID: https://orcid.org/0000-0003-2526-1621, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Leiz, J. ORCID: https://orcid.org/0000-0002-6531-7047, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Cao, S. ORCID: https://orcid.org/0000-0001-7195-8193, Skopnik, C.M. ORCID: https://orcid.org/0000-0002-6089-4769, Klocke, J. ORCID: https://orcid.org/0000-0002-7723-9234, Hardenberg, J.H. ORCID: https://orcid.org/0000-0001-9548-2118, Stockmann, H. ORCID: https://orcid.org/0000-0002-0934-7620, Gotthardt, I. ORCID: https://orcid.org/0000-0001-6033-0093, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Bachmann, S., Hocke, A.C. ORCID: https://orcid.org/0000-0002-6935-8612, Corman, V., Busch, J., Schneider, W., Himmerkus, N. ORCID: https://orcid.org/0000-0002-2910-6728, Bleich, M. ORCID: https://orcid.org/0000-0002-1745-2295, Eckardt, K.U. ORCID: https://orcid.org/0000-0003-3823-0920, Enghard, P. ORCID: https://orcid.org/0000-0002-7254-3931, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142
Genome Medicine 14
(1): 103.
9 September 2022
Human alveolar progenitors generate dual lineage bronchioalveolar organoids.
Hoffmann, K., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Hönzke, K., Fatykhova, D., Demir, Z. ORCID: https://orcid.org/0000-0001-5329-5517, Löwa, A. ORCID: https://orcid.org/0000-0002-5551-731X, Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Lopez-Rodriguez, E., Mieth, M., Baumgardt, M., Hoppe, J., Firsching, T.C. ORCID: https://orcid.org/0000-0003-1378-4951, Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Gruber, A.D. ORCID: https://orcid.org/0000-0002-4502-0393, Ochs, M. ORCID: https://orcid.org/0000-0002-0936-6979, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Suttorp, N., Hippenstiel, S., Hocke, A.C. and Kessler, M. ORCID: https://orcid.org/0000-0002-9879-1052
Communications Biology 5
(1): 875.
25 August 2022
MACC1-induced collective migration is promoted by proliferation rather than single cell biomechanics.
Hohmann, T. ORCID: https://orcid.org/0000-0002-0304-7221, Hohmann, U. ORCID: https://orcid.org/0000-0001-8376-4767, Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Dehghani, F. ORCID: https://orcid.org/0000-0002-7615-8854
Cancers 14
(12): 2857.
9 June 2022
Inflammation in children with chronic kidney disease linked to gut dysbiosis and metabolite imbalance.
Holle, J. ORCID: https://orcid.org/0000-0001-8032-4096, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Löber, U. ORCID: https://orcid.org/0000-0001-7468-9531, Behrens, F. ORCID: https://orcid.org/0000-0002-6841-4192, Bartolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Anandakumar, H. ORCID: https://orcid.org/0009-0000-3326-5126, Wimmer, M. ORCID: https://orcid.org/0009-0004-5793-0249, Vu, D.L., Kuhring, M. ORCID: https://orcid.org/0000-0002-3287-0313, Brüning, U. ORCID: https://orcid.org/0000-0003-0112-4032, Maifeld, A. ORCID: https://orcid.org/0000-0001-8756-747X, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Schumacher, F., Kleuser, B., Bufler, P., Querfeld, U., Kitschke, S., Engler, D., Kuhrt, L.D. ORCID: https://orcid.org/0000-0001-7157-6988, Drechsel, O., Eckardt, K.U., Forslund, S. ORCID: https://orcid.org/0000-0003-4285-6993, Thürmer, A., McParland, V. ORCID: https://orcid.org/0000-0003-0731-3272, Kirwan, J. ORCID: https://orcid.org/0000-0002-5423-1651, Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364 and Mueller, D.
Journal of the American Society of Nephrology 33
(12): 2259-2275.
December 2022
Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
Houwaart, Torsten, Belhaj, S., Tawalbeh, E., Nagels, D., Fröhlich, Y., Finzer, P., Ciruela, P., Sabrià, A., Herrero, M., Andrés, C., Antón, A., Benmoumene, A., Asskali, D., Haidar, H., von Dahlen, J., Nicolai, J., Stiller, M., Blum, J., Lange, C., Adelmann, C., Schroer, B., Osmers, U., Grice, C., Kirfel, P.P., Jomaa, H., Strelow, D., Hülse, L., Pigulla, M., Kreuzer, P., Tyshaieva, A., Weber, J., Wienemann, T., Kohns Vasconcelos, M., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Scholz, C.J., Jazmati, N., Göbels, K., Zotz, R., Pfeffer, K., Timm, J., Ehlkes, L., Walker, A. and Dilthey, A.T.
Eurosurveillance 27
(43): 2101089.
27 October 2022
Protocol for fast scRNA-seq raw data processing using scKB and non-arbitrary quality control with COPILOT.
Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Shahan, R., Nolan, T.M., Benfey, P.N. and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
STAR Protocols 3
(4): 101729.
16 December 2022
Cellular drivers of injury response and regeneration in the adult zebrafish heart.
Hu, B. ORCID: https://orcid.org/0000-0003-0751-885X, Lelek, S., Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Simões, M.G. ORCID: https://orcid.org/0000-0002-7340-9128, Aliee, H., Schäfer, R., Theis, F., Panáková, D. ORCID: https://orcid.org/0000-0002-8739-6225 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
[Dataset]
16 August 2022
Origin and function of activated fibroblast states during zebrafish heart regeneration.
Hu, B. ORCID: https://orcid.org/0000-0003-0751-885X, Lelek, S., Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, El-Sammak, H. ORCID: https://orcid.org/0000-0002-0178-1457, Simões, M.G. ORCID: https://orcid.org/0000-0002-7340-9128, Mintcheva, J. ORCID: https://orcid.org/0000-0003-0793-6277, Aliee, H., Schäfer, R., Meyer, A.M. ORCID: https://orcid.org/0000-0002-4665-2077, Theis, F. ORCID: https://orcid.org/0000-0002-2419-1943, Stainier, D.Y.R. ORCID: https://orcid.org/0000-0002-0382-0026, Panáková, D. ORCID: https://orcid.org/0000-0002-8739-6225 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Nature Genetics 54
(8): 1227-1237.
August 2022
Calorie restriction enhanced glycogen metabolism to compensate for lipid insufficiency.
Hu, L., Xia, X., Zong, Y., Gu, Y., Wei, L. and Yin, J.
Molecular Nutrition & Food Research 66
(20): 2200182.
October 2022
Women in the European Virus Bioinformatics Center.
Hufsky, F. ORCID: https://orcid.org/0000-0002-9489-3182, Abecasis, A. ORCID: https://orcid.org/0000-0002-3903-5265, Agudelo-Romero, P. ORCID: https://orcid.org/0000-0002-3703-4111, Bletsa, M. ORCID: https://orcid.org/0000-0003-3184-6618, Brown, K. ORCID: https://orcid.org/0000-0002-8400-6922, Claus, C. ORCID: https://orcid.org/0000-0003-4962-6568, Deinhardt-Emmer, S. ORCID: https://orcid.org/0000-0003-4495-4052, Deng, L. ORCID: https://orcid.org/0000-0003-0225-0663, Friedel, C.C. ORCID: https://orcid.org/0000-0003-3569-4877, Gismondi, M.I. ORCID: https://orcid.org/0000-0002-2566-1169, Kostaki, E.G. ORCID: https://orcid.org/0000-0002-3346-0930, Kühnert, D. ORCID: https://orcid.org/0000-0002-5657-018X, Kulkarni-Kale, U. ORCID: https://orcid.org/0000-0002-1168-2479, Metzner, K.J. ORCID: https://orcid.org/0000-0003-4862-1503, Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479, Miozzi, L. ORCID: https://orcid.org/0000-0003-0410-8230, Nishimura, L. ORCID: https://orcid.org/0000-0003-2144-7867, Paraskevopoulou, S. ORCID: https://orcid.org/0000-0003-2608-2596, Pérez-Cataluña, A. ORCID: https://orcid.org/0000-0002-4784-8346, Rahlff, J. ORCID: https://orcid.org/0000-0002-2132-2709, Thomson, E. ORCID: https://orcid.org/0000-0003-1482-0889, Tumescheit, C. ORCID: https://orcid.org/0000-0002-7563-5575, van der Hoek, L. ORCID: https://orcid.org/0000-0003-2803-642X, Van Espen, L. ORCID: https://orcid.org/0000-0002-3870-4551, Vandamme, A.M. ORCID: https://orcid.org/0000-0002-6594-2766, Zaheri, M. ORCID: https://orcid.org/0000-0003-2777-835X, Zuckerman, N. ORCID: https://orcid.org/0000-0001-6074-2100 and Marz, M. ORCID: https://orcid.org/0000-0003-4783-8823
Viruses 14
(7): 1522.
12 July 2022
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
Hung, K.L. ORCID: https://orcid.org/0000-0002-3662-4662, Luebeck, J. ORCID: https://orcid.org/0000-0003-4391-979X, Dehkordi, S.R., Colón, C.I., Li, R. ORCID: https://orcid.org/0000-0002-3085-5267, Wong, I.T.L., Coruh, C., Dharanipragada, P., Lomeli, S.H., Weiser, N.E. ORCID: https://orcid.org/0000-0001-9971-2961, Moriceau, G., Zhang, X. ORCID: https://orcid.org/0000-0003-1706-2868, Bailey, C., Houlahan, K.E., Yang, W., González, R.C. ORCID: https://orcid.org/0000-0002-5653-7259, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018, Curtis, C., Jamal-Hanjani, M. ORCID: https://orcid.org/0000-0003-1212-1259, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Law, J.A. ORCID: https://orcid.org/0000-0001-7472-7753, Greenleaf, W.J. ORCID: https://orcid.org/0000-0003-1409-3095, Lo, R.S. ORCID: https://orcid.org/0000-0002-5337-5004, Mischel, P.S. ORCID: https://orcid.org/0000-0002-4560-2211, Bafna, V. ORCID: https://orcid.org/0000-0002-5810-6241 and Chang, H.Y. ORCID: https://orcid.org/0000-0002-9459-4393
Nature Genetics 54
(11): 1746–1754.
November 2022
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke, K., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Mache, C., Fathykova, D., Kessler, M., Dökel, S., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Baumgardt, M., Löwa, A. ORCID: https://orcid.org/0000-0002-5551-731X, Hoffmann, K., Graff, P., Schulze, J., Mieth, M., Hellwig, K., Demir, Z., Biere, B., Brunotte, L., Mecate-Zambrano, A., Bushe, J., Dohmen, M. ORCID: https://orcid.org/0000-0002-4447-0579, Hinze, C. ORCID: https://orcid.org/0000-0003-2526-1621, Elezkurtaj, S., Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142, Busch, J., Klauschen, F., Horst, D., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Radke, J., Heppner, F., Corman, V.M., Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Müller, M.A., Goffinet, C., Mothes, R., Pascual-Reguant, A., Hauser, A.E., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Ludwig, S., Suttorp, N., Witzenrath, M., Gruber, A.D., Drosten, C., Sander, L.E., Wolff, T., Hippenstiel, S. and Hocke, A.C.
European Respiratory Journal 60
(6): 2102725.
1 December 2022
Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow, J., Gross, S., Busack, L., Flörcken, A., Jesse, J., Schwarz, M., Neuendorff, N.R., von Brünneck, A.C., Anagnostopoulos, I., Türkmen, S., Blau, I.W., Burmeister, T., Horst, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Westermann, J.
Haematologica 107
(8): 1773-1785.
August 2022
H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2(+) patients with diffuse midline glioma.
Immisch, L. ORCID: https://orcid.org/0000-0001-5072-8583, Papafotiou, G., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X
Journal for ImmunoTherapy of Cancer 10
(10): e005535.
27 October 2022
Impact of the first COVID-19 lockdown in Germany on the rate of acute infections during intensive chemotherapy for Hodgkin lymphoma.
Jacob, A.S., Kaul, H., Fuchs, M., Gillessen, S., Kreissl, S., Pluetschow, A., Momotow, J., Schaub, V., Huettmann, A., Haenel, M., Zimmermann, A., Dierlamm, J., Meissner, J., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Martin, S., Engert, A., Hallek, M., Borchmann, P. and Lehmann, C.
Infection 50
(4): 925-932.
August 2022
Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.
Jahn, N., Jahn, E., Saadati, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Larson, R.A. ORCID: https://orcid.org/0000-0001-9168-3203, Ottone, T., Amadori, S., Prior, T.W., Brandwein, J.M., Appelbaum, F.R., Medeiros, B.C. ORCID: https://orcid.org/0000-0001-6972-8137, Tallman, M.S., Ehninger, G., Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Ganser, A., Pallaud, C., Gathmann, I., Krzykalla, J., Benner, A., Bloomfield, C.D. ORCID: https://orcid.org/0000-0001-5465-7591, Thiede, C. ORCID: https://orcid.org/0000-0003-1241-2048, Stone, R.M. ORCID: https://orcid.org/0000-0002-7526-2633, Döhner, H. and Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862
Leukemia 36
(9): 2218-2227.
September 2022
Semi-automated assembly of high-quality diploid human reference genomes.
Jarvis, E.D. ORCID: https://orcid.org/0000-0001-8931-5049, Formenti, G. ORCID: https://orcid.org/0000-0002-7554-5991, Rhie, A., Guarracino, A. ORCID: https://orcid.org/0000-0001-9744-131X, Yang, C., Wood, J. ORCID: https://orcid.org/0000-0002-7545-2162, Tracey, A. ORCID: https://orcid.org/0000-0002-4805-9058, Thibaud-Nissen, F. ORCID: https://orcid.org/0000-0003-4957-7807, Vollger, M.R. ORCID: https://orcid.org/0000-0002-8651-1615, Porubsky, D. ORCID: https://orcid.org/0000-0001-8414-8966, Cheng, H., Asri, M., Logsdon, G.A. ORCID: https://orcid.org/0000-0003-2396-0656, Carnevali, P., Chaisson, M.J.P. ORCID: https://orcid.org/0000-0001-5395-1457, Chin, C.S., Cody, S., Collins, J., Ebert, P. ORCID: https://orcid.org/0000-0001-7441-532X, Escalona, M. ORCID: https://orcid.org/0000-0003-0213-4777, Fedrigo, O. ORCID: https://orcid.org/0000-0002-6450-7551, Fulton, R.S., Fulton, L.L., Garg, S., Gerton, J.L. ORCID: https://orcid.org/0000-0003-0743-3637, Ghurye, J., Granat, A., Green, R.E. ORCID: https://orcid.org/0000-0003-0516-5827, Harvey, W., Hasenfeld, P. ORCID: https://orcid.org/0000-0003-2319-2482, Hastie, A., Haukness, M. ORCID: https://orcid.org/0000-0001-9991-8089, Jaeger, E.B., Jain, M., Kirsche, M., Kolmogorov, M. ORCID: https://orcid.org/0000-0002-5489-9045, Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794, Koren, S. ORCID: https://orcid.org/0000-0002-1472-8962, Korlach, J. ORCID: https://orcid.org/0000-0003-3047-4250, Lee, J. ORCID: https://orcid.org/0000-0002-3492-1102, Li, D. ORCID: https://orcid.org/0000-0001-7492-3703, Lindsay, T., Lucas, J., Luo, F. ORCID: https://orcid.org/0000-0002-4813-2403, Marschall, T. ORCID: https://orcid.org/0000-0002-9376-1030, Mitchell, M.W., McDaniel, J. ORCID: https://orcid.org/0000-0003-1987-0914, Nie, F., Olsen, H.E., Olson, N.D. ORCID: https://orcid.org/0000-0003-2585-3037, Pesout, T., Potapova, T., Puiu, D., Regier, A., Ruan, J., Salzberg, S.L., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Schatz, M.C., Schmitt, A., Schneider, V.A., Selvaraj, S., Shafin, K. ORCID: https://orcid.org/0000-0001-5252-3434, Shumate, A., Stitziel, N.O. ORCID: https://orcid.org/0000-0002-4963-8211, Stober, C., Torrance, J., Wagner, J., Wang, J. ORCID: https://orcid.org/0000-0003-1516-0480, Wenger, A., Xiao, C. ORCID: https://orcid.org/0000-0002-4680-0682, Zimin, A.V., Zhang, G. ORCID: https://orcid.org/0000-0001-6860-1521, Wang, T. ORCID: https://orcid.org/0000-0002-6800-242X, Li, H. ORCID: https://orcid.org/0000-0003-4874-2874, Garrison, E., Haussler, D. ORCID: https://orcid.org/0000-0003-1533-4575, Hall, I., Zook, J.M., Eichler, E.E. ORCID: https://orcid.org/0000-0002-8246-4014, Phillippy, A.M. ORCID: https://orcid.org/0000-0003-2983-8934, Paten, B., Howe, K. ORCID: https://orcid.org/0000-0003-2237-513X and Miga, K.H.
Nature 611
(7936): 519-531.
17 November 2022
Efficacy and feasibility of proton beam therapy in relapsed high-risk neuroblastoma-experiences from the prospective KiProReg registry.
Jazmati, D., Hero, B., Thole-Kliesch, T.M., Merta, J., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Bäumer, C. ORCID: https://orcid.org/0000-0003-0512-1146, Heinzelmann, F., Schleithoff, S.S., Koerber, F., Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Schwarz, R., Simon, T. ORCID: https://orcid.org/0000-0002-3425-8451 and Timmermann, B.
Current Oncology 29
(11): 8222-8234.
November 2022
Accelerating clinical scale production of BCMA CAR T cells with defined maturation stages.
Joedicke, J.J. ORCID: https://orcid.org/0000-0002-4708-3216, Großkinsky, U., Gerlach, K., Künkele, A., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Molecular Therapy - Methods and Clinical Development 24
: 181-198.
10 March 2022
Transient activated fibroblasts contribute to zebrafish heart regeneration.
Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Panáková, D. ORCID: https://orcid.org/0000-0002-8739-6225
Nature Genetics 54
(8): 1076-1077.
August 2022
Significant reduced loss of bone mineral density after four vs. six cycles of R-CHOP: an analysis of the FLYER-trial.
Kaddu-Mulindwa, D. ORCID: https://orcid.org/0000-0001-8832-252X, Lesan, V., Berdel, C., Stilgenbauer, S., Bewarder, M., Thurner, L., Witzens-Harig, M., Viardot, A. ORCID: https://orcid.org/0000-0001-9593-6327, Soekler, M., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Truemper, L., Christofyllakis, K., Fleser, O., Bittenbring, J.T., Poeschel, V., Held, G. and Jagoda, P.
Leukemia & Lymphoma 63
(2): 326-334.
February 2022
Small molecule inhibitors for hepatocellular carcinoma: advances and challenges.
Kamal, M.A., Mandour, Y.M. ORCID: https://orcid.org/0000-0001-7104-3268, Abd El-Aziz, M.K. ORCID: https://orcid.org/0000-0003-0252-5065, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and El Tayebi, H.M. ORCID: https://orcid.org/0000-0002-6896-6018
Molecules 27
(17): 5537.
1 September 2022
BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Maertzdorf, J., Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Muellerke, S., Zuo, X. ORCID: https://orcid.org/0000-0002-8593-1132, Vidal, R. ORCID: https://orcid.org/0000-0003-4217-2014, Shureiqi, I. ORCID: https://orcid.org/0000-0003-2019-938X, Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Kidess, E., Mollenkopf, H.J. ORCID: https://orcid.org/0000-0003-1167-4783, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Meyer, T.F. ORCID: https://orcid.org/0000-0002-6120-8679 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Nature Communications 13
(1): 1577.
24 March 2022
Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath, J., Du, W., Pruene, A., Braun, T., Thommandru, B., Turk, R., Sturgeon, M.L., Kurgan, G.L., Amini, L., Stein, M., Zittel, T., Martini, S., Ostendorf, L., Wilhelm, A., Akyüz, L., Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950, Hoepken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Pruß, A., Künkele, A., Jacobi, A.M., Volk, H.D., Schmueck-Henneresse, M., Stripecke, R., Reinke, P. and Wagner, D.L.
Molecular Therapy - Methods and Clinical Development 25
: 311-330.
9 June 2022
Identification of early neurodegenerative pathways in progressive multiple sclerosis.
Kaufmann, M. ORCID: https://orcid.org/0000-0002-1954-4425, Schaupp, A.L., Sun, R. ORCID: https://orcid.org/0000-0002-4979-1574, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Dendrou, C.A., Cortes, A., Kaur, G. ORCID: https://orcid.org/0000-0001-7722-3956, Evans, H.G., Mollbrink, A., Navarro, J.F. ORCID: https://orcid.org/0000-0002-4035-5258, Sonner, J.K. ORCID: https://orcid.org/0000-0002-4700-272X, Mayer, C., DeLuca, G.C. ORCID: https://orcid.org/0000-0003-0342-5197, Lundeberg, J. ORCID: https://orcid.org/0000-0003-4313-1601, Matthews, P.M. ORCID: https://orcid.org/0000-0002-1619-8328, Attfield, K.E., Friese, M.A. ORCID: https://orcid.org/0000-0001-6380-2420, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799 and Fugger, L. ORCID: https://orcid.org/0000-0003-2883-3226
Nature Neuroscience 25
(7): 944-955.
July 2022
MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.
Kaufmann, T.L. ORCID: https://orcid.org/0000-0003-4374-1338, Petkovic, M. ORCID: https://orcid.org/0000-0003-2875-216X, Watkins, T.B.K. ORCID: https://orcid.org/0000-0001-7414-737X, Colliver, E.C. ORCID: https://orcid.org/0000-0002-1497-0740, Laskina, S., Thapa, N., Minussi, D.C. ORCID: https://orcid.org/0000-0001-8856-4625, Navin, N. ORCID: https://orcid.org/0000-0002-2106-8624, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018, Van Loo, P. ORCID: https://orcid.org/0000-0003-0292-1949, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Tarabichi, M. ORCID: https://orcid.org/0000-0002-1635-2348 and Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268
Genome Biology 23
(1): 241.
14 November 2022
A brief introduction to current cancer gene therapy.
Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Pahle, J. and Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231
Methods in Molecular Biology 2521
(3): 1-21.
23 June 2022
Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.
Kofla, G., Radecke, C., Frentsch, M., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Stintzing, S., Riess, H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
OncoImmunology 11
(1): 2068109.
25 April 2022
Simultaneous dimensionality reduction and integration for single-cell ATAC-seq data using deep learning.
Kopp, W. ORCID: https://orcid.org/0000-0003-0376-0032, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Nature Machine Intelligence 4
(2): 162-168.
February 2022
Single-cell multi-omics allows functional characterization of structural variants.
Korbel, J.O. and Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677
Nature Biotechnology
24 November 2022
EASIX and severe endothelial complications after CD19-directed CAR-T Cell therapy-a cohort study.
Korell, F., Penack, O., Mattie, M., Schreck, N., Benner, A., Krzykalla, J., Wang, Z., Schmitt, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Müller-Tidow, C., Dreger, P. and Luft, T.
Frontiers in Immunology 13
: 877477.
8 April 2022
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis.
Kortüm, B. ORCID: https://orcid.org/0000-0003-3734-6665, Radhakrishnan, H., Zincke, F., Sachse, C., Burock, S., Keilholz, U., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Oncogene 41
(39): 4446-4458.
23 September 2022
Deletion in the Y chromosome of B10.BR-Y(del) mice alters transcription from MSYq genes and has moderate effect on DNA methylation.
Kotarska, K. ORCID: https://orcid.org/0000-0003-3235-9475, Doniec, A. ORCID: https://orcid.org/0000-0002-2401-2095, Korostyński, M. ORCID: https://orcid.org/0000-0002-4273-7401, Piechota, M., Gołas, A., Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072 and Styrna, J.
Reproductive Biology 22
(2): 100614.
June 2022
Reduced splenic uptake on (68)Ga-Pentixafor-PET/CT imaging in multiple myeloma - a potential imaging biomarker for disease prognosis.
Kraus, S., Klassen, P., Kircher, M., Dierks, A., Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Gäble, A., Kortüm, K.M., Weinhold, N., Ademaj-Kospiri, V., Werner, R.A., Schirbel, A., Buck, A.K., Herhaus, P., Wester, H.J., Rosenwald, A., Weber, W.A., Einsele, H., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Rasche, L. and Lapa, C.
Theranostics 12
(13): 5986-5994.
8 August 2022
A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse.
Krause, F., Mohebian, K. ORCID: https://orcid.org/0000-0002-7337-5132, Delpero, M., Hesse, D. ORCID: https://orcid.org/0000-0001-5915-8003, Kuehn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Arends, D. ORCID: https://orcid.org/0000-0001-8738-0162 and Brockmann, G.A. ORCID: https://orcid.org/0000-0002-4387-2947
Mammalian Genome 33
(3): 465–470.
September 2022
Small cell lung cancer stem cells display mesenchymal properties and exploit immune checkpoint pathways in activated cytotoxic T lymphocytes.
Kursunel, M.A. ORCID: https://orcid.org/0000-0002-2483-1920, Taskiran, E.Z., Tavukcuoglu, E., Yanik, H., Demirag, F., Karaosmanoglu, B., Ozbay, F.G., Uner, A., Esendagli, D., Kizilgoz, D., Yilmaz, U. and Esendagli, G.
Cancer Immunology Immunotherapy 71
(2): 445-459.
February 2022
Genome engineering in rodents - status quo and perspectives.
Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803
Laboratory Animals 56
(1): 83-87.
1 February 2022
Rapid single-cell identification of Epstein-Barr virus-specific T-cell receptors for cellular therapy.
Lammoglia Cobo, M.F. ORCID: https://orcid.org/0000-0002-0369-0364, Welters, C. ORCID: https://orcid.org/0000-0002-3098-9003, Rosenberger, L., Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142, Dietze, K., Pircher, C., Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Gary, R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Takvorian, A., Moosmann, A., Dornmair, K. ORCID: https://orcid.org/0000-0003-0342-5373, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Kammertöns, T. ORCID: https://orcid.org/0000-0003-3309-5141, Gerbitz, A. ORCID: https://orcid.org/0000-0002-0105-2086 and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
Cytotherapy 24
(8): 818-826.
August 2022
Multimodal single cell data integration challenge: results and lessons learned.
Lance, C., Luecken, M.D., Burkhardt, D.B., Cannoodt, R., Rautenstrauch, P. ORCID: https://orcid.org/0000-0002-0070-4759, Laddach, A.C., Ubingazhibov, A., Cao, Z.J., Deng, K., Khan, S., Liu, Q., Russkikh, N., Ryazantsev, G., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Pisco, A.O., Bloom, J.M., Krishnaswamy, S. and Theis, F.J.
In: NeurIPS 2021: Thirty-Fifth Annual Conference on Neural Information Processing Systems, 06-14 Dec 2021, San Diego, CA.
2022
The evolutionary dynamics of extrachromosomal DNA in human cancers.
Lange, J.T. ORCID: https://orcid.org/0000-0002-4246-6058, Rose, J.C. ORCID: https://orcid.org/0000-0003-1810-4337, Chen, C.Y. ORCID: https://orcid.org/0000-0002-1579-024X, Pichugin, Y., Xie, L., Tang, J., Hung, K.L. ORCID: https://orcid.org/0000-0002-3662-4662, Yost, K.E., Shi, Q., Erb, M.L., Rajkumar, U., Wu, S. ORCID: https://orcid.org/0000-0001-8329-7492, Taschner-Mandl, S. ORCID: https://orcid.org/0000-0002-1439-5301, Bernkopf, M. ORCID: https://orcid.org/0000-0001-6650-4592, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018, Liu, Z. ORCID: https://orcid.org/0000-0002-3592-3150, Huang, W. ORCID: https://orcid.org/0000-0002-9016-2665, Chang, H.Y. ORCID: https://orcid.org/0000-0002-9459-4393, Bafna, V. ORCID: https://orcid.org/0000-0002-5810-6241, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Werner, B. ORCID: https://orcid.org/0000-0002-6857-8699 and Mischel, P.S. ORCID: https://orcid.org/0000-0002-4560-2211
Nature Genetics 54
(10): 1527-1533.
October 2022
A flexible tool to correct superimposed mass isotopologue distributions in GC-APCI-MS flux experiments.
Langenhan, J., Jaeger, C. ORCID: https://orcid.org/0000-0003-2192-1792, Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Simon, M. ORCID: https://orcid.org/0000-0001-7213-9499 and Lisec, J. ORCID: https://orcid.org/0000-0003-1220-2286
Metabolites 12
(5): 408.
29 April 2022
Sox9 is required for nail bed differentiation and digit tip regeneration.
Lao, M. ORCID: https://orcid.org/0000-0001-6707-6825, Hurtado, A. ORCID: https://orcid.org/0000-0001-6267-704X, de Castro, A.C. ORCID: https://orcid.org/0000-0003-0497-469X, Burgos, M. ORCID: https://orcid.org/0000-0003-4446-9313, Jiménez, R. ORCID: https://orcid.org/0000-0003-4103-8219 and Barrionuevo, F.J. ORCID: https://orcid.org/0000-0003-2651-1530
Journal of Investigative Dermatology 142
(10): 2613-2622.
October 2022
Editorial: Lineage tracing, hematopoietic stem cell and immune cell dynamics.
Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Romagnani, C. and Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164
Frontiers in Immunology 13
: 1062415.
18 October 2022
Efficient CRISPR/Cas9-mediated mutagenesis in primary human B cells for identifying plasma cell regulators.
Le, T.A., Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696, Lino, A.C., Schrezenmeier, E. ORCID: https://orcid.org/0000-0002-0016-7885, Kressler, C., Hamo, D., Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Dörner, T. and Dang, V.D.
Molecular Therapy - Nucleic Acids 30
: 621-632.
13 December 2022
Different classes of genomic inserts contribute to human antibody diversity.
Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195, Foglierini, M., Khorkova, S. ORCID: https://orcid.org/0000-0002-7873-2290, Vázquez García, C. ORCID: https://orcid.org/0000-0003-4583-7616, Ratswohl, C. ORCID: https://orcid.org/0000-0001-5413-0730, Davydov, A.N., Turchaninova, M.A. ORCID: https://orcid.org/0000-0002-8874-0286, Daubenberger, C. ORCID: https://orcid.org/0000-0001-7136-0642, Chudakov, D.M. ORCID: https://orcid.org/0000-0003-0430-790X, Lanzavecchia, A. and de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157
Proceedings of the National Academy of Sciences of the United States of America 119
(36): e2205470119.
6 September 2022
Morphine alleviates pain after heart cryonjury in zebrafish without impeding regeneration.
Lelek, S., Guedes Simões, M., Hu, B. ORCID: https://orcid.org/0000-0003-0751-885X, Alameldeen, A.M., Czajkowski, M.T. ORCID: https://orcid.org/0000-0002-0122-1943, Meyer, A.M. ORCID: https://orcid.org/0000-0002-4665-2077, Ferrara, F., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Pánákova, D. ORCID: https://orcid.org/0000-0002-8739-6225
[Dataset]
16 August 2022
Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M. ORCID: https://orcid.org/0000-0002-8039-9415, Wang, Y.H. ORCID: https://orcid.org/0000-0002-3637-8852, Kaufmann, U. ORCID: https://orcid.org/0000-0003-4317-5794, Gerbeth, L. ORCID: https://orcid.org/0000-0001-6638-1959, Sand, A., Brunkhorst, M., Weidner, P. ORCID: https://orcid.org/0000-0003-2448-5981, Ziegler, J.F. ORCID: https://orcid.org/0000-0001-7445-541X, Böttcher, C. ORCID: https://orcid.org/0000-0002-6226-586X, Schlickeiser, S., Fernández, C., Yamashita, M., Stauderman, K. ORCID: https://orcid.org/0000-0002-8090-4549, Sun, K., Kunkel, D., Prakriya, M., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Siegmund, B., Feske, S. ORCID: https://orcid.org/0000-0001-5431-8178 and Weidinger, C. ORCID: https://orcid.org/0000-0002-9948-0088
EMBO Molecular Medicine 14
(9): e15687.
7 September 2022
Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D., Oshima, M., Stange, D.E. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Gastroenterology 162
(4): 1067-1087.
April 2022
Mako: a graph-based pattern growth approach to detect complex structural variants.
Lin, J., Yang, X., Kosters, W., Xu, T., Jia, Y., Wang, S., Zhu, Q., Ryan, M., Guo, L., Zhang, C., Lee, C., Devine, S.E., Eichler, E.E. and Ye, K.
Genomics, Proteomics and Bioinformatics 20
(1): 205-218.
February 2022
Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo, W.T. ORCID: https://orcid.org/0000-0001-7904-6834, Zhang, Y., Vadas, O. ORCID: https://orcid.org/0000-0003-3511-6479, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Gulluni, F., De Santis, M.C. ORCID: https://orcid.org/0000-0003-2785-0665, Zagar, A.V., Stephanowitz, H., Hirsch, E., Liu, F. ORCID: https://orcid.org/0000-0002-2358-549X, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993
Nature Structural & Molecular Biology 29
(3): 218-228.
March 2022
Circulating cell-free DNA assessment in biofluids from children with neuroblastoma demonstrates feasibility and potential for minimally invasive molecular diagnostics.
Lodrini, M., Wünschel, J., Thole-Kliesch, T.M., Grimaldi, M., Sprüssel, A., Linke, R.B., Hollander, J.F., Tiburtius, D., Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Lankes, E., Elgeti, T. ORCID: https://orcid.org/0000-0002-7155-6044, Hundsdörfer, P., Astrahantseff, K., Simon, T., Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184 and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Cancers 14
(9): 2080.
21 April 2022
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Bao, E.L., Liu, N. ORCID: https://orcid.org/0000-0002-8314-0900, Utsugisawa, T., Tseng, A.M., Myers, S.A. ORCID: https://orcid.org/0000-0001-7636-0887, Verboon, J.M. ORCID: https://orcid.org/0000-0002-4454-6043, Ulirsch, J.C., Luo, W., Muus, C., Fiorini, C., Olive, M.E. ORCID: https://orcid.org/0000-0001-8287-9474, Vockley, C.M., Munschauer, M., Hunter, A., Ogura, H., Yamamoto, T. ORCID: https://orcid.org/0000-0002-9484-3505, Inada, H., Nakagawa, S., Ozono, S. ORCID: https://orcid.org/0000-0003-0009-9365, Subramanian, V., Chiarle, R. ORCID: https://orcid.org/0000-0003-1564-8531, Glader, B., Carr, S.A., Aryee, M.J. ORCID: https://orcid.org/0000-0002-6848-1344, Kundaje, A. ORCID: https://orcid.org/0000-0003-3084-2287, Orkin, S., Regev, A., McCavit, T., Kanno, H. and Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X
Blood 139
(16): 2534-2546.
21 April 2022
Tongue immune compartment analysis reveals spatial macrophage heterogeneity.
Lyras, E.M. ORCID: https://orcid.org/0000-0003-3269-0854, Zimmermann, K., Wagner, L.K., Dörr, D. ORCID: https://orcid.org/0000-0001-8575-7560, Klose, C.S.N, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Jung, S. ORCID: https://orcid.org/0000-0003-4290-5716, Yona, S. ORCID: https://orcid.org/0000-0002-3984-2008, Hovav, A.H., Stenzel, W., Dommerich, S., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X and Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427
eLife 11
: 77490.
24 June 2022
In vitro Kinase-to-Phosphosite database (iKiP-DB) predicts kinase activity in phosphoproteomic datasets.
Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, Mösbauer, K., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Drosten, C. and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Journal of Proteome Research 21
(6): 1575-1587.
3 June 2022
Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F. ORCID: https://orcid.org/0000-0001-5696-9679, Jerke, U. ORCID: https://orcid.org/0000-0001-6887-8010, Rolle, S. ORCID: https://orcid.org/0000-0002-1909-687X, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718
Journal of Biological Chemistry 298
(3): 101598.
March 2022
Towards reliable quantification of cell state velocities.
Marot-Lassauzaie, V. ORCID: https://orcid.org/0000-0002-8362-9634, Bouman, B.J. ORCID: https://orcid.org/0000-0003-1259-5040, Donaghy, F.D. ORCID: https://orcid.org/0000-0001-6892-0186, Demerdash, Y., Essers, M.A.G. and Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170
PLoS Computational Biology 18
(9): e1010031.
28 September 2022
Infectious complications of targeted drugs and biotherapies in acute leukemia. Clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL), a joint venture of the European Group for Blood and Marrow Transplantation (EBMT), the European Organization for Research and Treatment of Cancer (EORTC), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN).
Maschmeyer, G. ORCID: https://orcid.org/0000-0003-2378-2466, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Garcia-Vidal, C., Herbrecht, R. ORCID: https://orcid.org/0000-0002-9381-4876, Maertens, J. ORCID: https://orcid.org/0000-0003-4257-5980, Menna, P., Pagano, L. ORCID: https://orcid.org/0000-0001-8287-928X, Thiebaut-Bertrand, A. and Calandra, T.
Leukemia 36
(5): 1215-1226.
May 2022
ATACing single cells with phages.
Maschmeyer, P. ORCID: https://orcid.org/0000-0002-1705-5302 and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Molecular Cell 82
(2): 234-236.
20 January 2022
Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
McGarvey, A.C. ORCID: https://orcid.org/0000-0003-3838-1139, Kopp, W. ORCID: https://orcid.org/0000-0003-0376-0032, Vučićević, D. ORCID: https://orcid.org/0000-0002-1162-6709, Mattonet, K. ORCID: https://orcid.org/0000-0002-9705-8086, Kempfer, R. ORCID: https://orcid.org/0000-0002-8588-8576, Hirsekorn, A., Bilić, I. ORCID: https://orcid.org/0000-0002-2730-1634, Gil, M. ORCID: https://orcid.org/0000-0002-3885-7806, Trinks, A. ORCID: https://orcid.org/0000-0001-9983-1506, Merks, A.M. ORCID: https://orcid.org/0000-0001-5677-7204, Panáková, D. ORCID: https://orcid.org/0000-0002-8739-6225, Pombo, A. ORCID: https://orcid.org/0000-0002-7493-6288, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290, Stainier, D.Y.R. ORCID: https://orcid.org/0000-0002-0382-0026, Garfield, D. ORCID: https://orcid.org/0000-0002-8790-797X, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340
Cell Genomics 2
(1): 100083.
13 January 2022
Physiological functions of intracellular protein degradation.
McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Annual Review of Cell and Developmental Biology 38
: 241-262.
October 2022
Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T. ORCID: https://orcid.org/0000-0002-7181-9369, Lindemann, P. ORCID: https://orcid.org/0000-0002-8224-3764, Welle, A., Trouillet, V., Heißler, S., Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
ChemMedChem 17
(19): e202200346.
6 October 2022
Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A., Sprink, T. ORCID: https://orcid.org/0000-0002-0760-6828, Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Vázquez-Sarandeses, E. ORCID: https://orcid.org/0009-0003-3526-7629, van Hoorn, C. ORCID: https://orcid.org/0000-0002-1319-847X, Mohd, S., Loerke, J. ORCID: https://orcid.org/0000-0002-3424-8536, Spahn, C.M.T. and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Nature Communications 13
(1): 7641.
10 December 2022
Analyses of murine lymph node endothelial cell subsets using single-cell RNA sequencing and spectral flow cytometry.
Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Zschummel, M. ORCID: https://orcid.org/0000-0002-4778-8742 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
STAR Protocols 3
(2): 101267.
17 June 2022
A high-resolution map of small-scale inversions in the gibbon genome.
Mercuri, L. ORCID: https://orcid.org/0000-0002-3688-4501, Palmisano, D., L'Abbate, A. ORCID: https://orcid.org/0000-0002-5995-2001, D'Addabbo, P. ORCID: https://orcid.org/0000-0003-3325-4931, Montinaro, F. ORCID: https://orcid.org/0000-0002-4506-963X, Catacchio, C.R. ORCID: https://orcid.org/0000-0002-2166-723X, Hasenfeld, P. ORCID: https://orcid.org/0000-0003-2319-2482, Ventura, M. ORCID: https://orcid.org/0000-0001-7762-8777, Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794, Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Maggiolini, F.A.M. ORCID: https://orcid.org/0000-0001-6832-9388 and Antonacci, F. ORCID: https://orcid.org/0000-0002-5833-6186
Genome Research 32
(10): 1941-1951.
October 2022
Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models.
Metzger, J.J. ORCID: https://orcid.org/0000-0001-6813-4425, Pereda, C. ORCID: https://orcid.org/0000-0003-1625-215X, Adhikari, A., Haremaki, T., Galgoczi, S., Siggia, E.D., Brivanlou, A.H. and Etoc, F.
Cell Reports Methods 2
(9): 100297.
19 September 2022
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt, L. ORCID: https://orcid.org/0000-0002-7909-020X, Braun, J., Fauchere, F., Vanshylla, K., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Jürchott, K., Mangold, M., Maraj, A., Braginets, A., Böttcher, C. ORCID: https://orcid.org/0000-0002-6226-586X, Nitsche, A., de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157, Ratswohl, C. ORCID: https://orcid.org/0000-0001-5413-0730, Sawitzki, B., Holenya, P., Reimer, U. ORCID: https://orcid.org/0000-0002-3375-6889, Sander, L.E., Klein, F., Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Bellmann-Strobl, J. ORCID: https://orcid.org/0000-0003-2615-1643, Thiel, A. and Giesecke-Thiel, C. ORCID: https://orcid.org/0000-0002-5927-7018
Journal of Neurology Neurosurgery and Psychiatry 93
(9): 960-971.
September 2022
Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C. ORCID: https://orcid.org/0000-0001-9852-677X, Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072, Lickfett, S., Mlody, B. ORCID: https://orcid.org/0000-0001-5184-1772, Bünning, M., Genehr, C., Ulrich, C., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Priller, J. ORCID: https://orcid.org/0000-0001-7596-0979 and Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952
Stem Cell Research 65
: 102976.
December 2022
Suicide nanoplasmids coding for ribosome-inactivating proteins.
Mitdank, H., Tröger, M., Sonntag, A., Shirazi, N.A., Woith, E., Fuchs, H., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Weng, A.
European Journal of Pharmaceutical Sciences 170
: 106107.
1 March 2022
Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.
Monti, R. ORCID: https://orcid.org/0000-0002-6354-8319, Rautenstrauch, P. ORCID: https://orcid.org/0000-0002-0070-4759, Ghanbari, M. ORCID: https://orcid.org/0000-0002-6015-2968, James, A.R. ORCID: https://orcid.org/0000-0001-6098-2761, Kirchler, M. ORCID: https://orcid.org/0000-0003-0616-2740, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Konigorski, S. ORCID: https://orcid.org/0000-0002-9966-6819 and Lippert, C. ORCID: https://orcid.org/0000-0001-6363-2556
Nature Communications 13
(1): 5332.
10 September 2022
Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis.
Moshkovits, I., Kaminitz, A., Reuveni, D., Pasmanik-Chor, M., Brazowski, E., Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427, Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X and Zigmond, E. ORCID: https://orcid.org/0000-0003-2956-1867
Immunity, inflammation and disease 10
(11): e728.
November 2022
Standardized annotation of translated open reading frames.
Mudge, J.M. ORCID: https://orcid.org/0000-0003-4789-7495, Ruiz-Orera, J. ORCID: https://orcid.org/0000-0002-8317-0034, Prensner, J.R. ORCID: https://orcid.org/0000-0002-7024-636X, Brunet, M.A. ORCID: https://orcid.org/0000-0001-5973-3522, Calvet, F. ORCID: https://orcid.org/0000-0003-1841-9881, Jungreis, I. ORCID: https://orcid.org/0000-0002-3197-5367, Gonzalez, Jo.M. ORCID: https://orcid.org/0000-0001-5569-0705, Magrane, M. ORCID: https://orcid.org/0000-0003-3544-996X, Martinez, T.F. ORCID: https://orcid.org/0000-0002-4011-8164, Schulz, J.F. ORCID: https://orcid.org/0000-0002-8157-2224, Yang, Y.T. ORCID: https://orcid.org/0000-0002-6873-5279, Albà, M.M., Aspden, J.L., Baranov, P.V. ORCID: https://orcid.org/0000-0001-9017-0270, Bazzini, A.A. ORCID: https://orcid.org/0000-0002-2251-5174, Bruford, E. ORCID: https://orcid.org/0000-0002-8380-5247, Martin, M.J., Calviello, L., Carvunis, A.R. ORCID: https://orcid.org/0000-0002-6474-6413, Chen, J. ORCID: https://orcid.org/0000-0002-6634-4397, Couso, J.P. ORCID: https://orcid.org/0000-0002-8547-7312, Deutsch, E.W. ORCID: https://orcid.org/0000-0001-8732-0928, Flicek, P. ORCID: https://orcid.org/0000-0002-3897-7955, Frankish, A., Gerstein, M., Hubner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Ingolia, N.T. ORCID: https://orcid.org/0000-0002-3395-1545, Kellis, M. ORCID: https://orcid.org/0000-0001-7113-9630, Menschaert, G., Moritz, R.L. ORCID: https://orcid.org/0000-0002-3216-9447, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Roucou, X. ORCID: https://orcid.org/0000-0001-9370-5584, Saghatelian, A. ORCID: https://orcid.org/0000-0002-0427-563X, Weissman, J.S. ORCID: https://orcid.org/0000-0003-2445-670X and van Heesch, S. ORCID: https://orcid.org/0000-0001-9593-1980
Nature Biotechnology 40
(7): 994–999.
July 2022
Deep Visual Proteomics defines single-cell identity and heterogeneity.
Mund, A. ORCID: https://orcid.org/0000-0002-7843-5341, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Kriston, A., Hollandi, R., Kovács, F., Brunner, A.D., Migh, E., Schweizer, L., Santos, A., Bzorek, M., Naimy, S., Rahbek-Gjerdrum, L.M. ORCID: https://orcid.org/0000-0003-4377-3209, Dyring-Andersen, B., Bulkescher, J., Lukas, C. ORCID: https://orcid.org/0000-0001-7169-6883, Eckert, M.A., Lengyel, E., Gnann, C., Lundberg, E. ORCID: https://orcid.org/0000-0001-7034-0850, Horvath, P. and Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799
Nature Biotechnology 40
(8): 1231-1240.
August 2022
Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D. ORCID: https://orcid.org/0000-0001-7959-454X, Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Bohl, S.R., Dolnik, A., Steinebach, C. ORCID: https://orcid.org/0000-0001-5638-1955, Conrad, T., Müller, S., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Kull, M., Haji, M., Gütschow, M., Döhner, H., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Krönke, J. ORCID: https://orcid.org/0000-0002-4649-0506
Nature Communications 13
(1): 1009.
23 February 2022
Gene gun Her2/neu DNA vaccination: evaluation of vaccine efficacy in a syngeneic Her2/neu mouse tumor model.
Nguyen-Hoai, T., Hohn, O., Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470 and Westermann, J.
Methods in Molecular Biology 2521
(3): 129-154.
23 June 2022
Generation of a NES-mScarlet red fluorescent reporter human iPSC line for live cell imaging and flow cytometric analysis and sorting using CRISPR-Cas9-mediated gene editing.
Nouri, P., Zimmer, A., Brüggemann, S., Friedrich, R., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803 and Prakash, N. ORCID: https://orcid.org/0000-0002-0568-6262
Cells 11
(2): 268.
13 January 2022
Familial long-read sequencing increases yield of de novo mutations.
Noyes, M.D., Harvey, W.T., Porubsky, D., Sulovari, A., Li, R., Rose, N.R., Audano, P.A., Munson, K.M., Lewis, A.P., Hoekzema, K., Mantere, T., Graves-Lindsay, T.A., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Goodwin, S., Kramer, M., Mokrab, Y., Zody, M.C., Hoischen, A., Korbel, J.O., McCombie, W.R. and Eichler, E.E.
American Journal of Human Genetics 109
(4): 631-646.
7 April 2022
Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla, T. ORCID: https://orcid.org/0000-0001-9527-8061, Gollasch, B., Kuich, P.H.J.L., Klug, L., Rahn, G., Busjahn, A. ORCID: https://orcid.org/0000-0001-9650-6919, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Boschmann, M. ORCID: https://orcid.org/0000-0002-0114-7114, Kirwan, J.A. ORCID: https://orcid.org/0000-0002-5423-1651, Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Frontiers in Molecular Biosciences 9
: 1042231.
21 December 2022
The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
Paulmann, C., Spallek, R., Karpiuk, O., Heider, M., Schäffer, I., Zecha, J. ORCID: https://orcid.org/0000-0002-8767-6294, Klaeger, S., Walzik, M., Öllinger, R. ORCID: https://orcid.org/0000-0002-2292-5982, Engleitner, T., Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Krönke, J., Rudelius, M., Kossatz, S., Rad, R. ORCID: https://orcid.org/0000-0002-6849-9659, Kuster, B. ORCID: https://orcid.org/0000-0002-9094-1677 and Bassermann, F. ORCID: https://orcid.org/0000-0003-4435-2609
EMBO Journal 41
(20): e110871.
17 October 2022
Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance.
Pecorino, L.T., Verhaak, R.G.W., Henssen, A. ORCID: https://orcid.org/0000-0003-1534-778X and Mischel, P.S. ORCID: https://orcid.org/0000-0002-4560-2211
Biochemical Society Transactions 50
(6): 1911-1920.
December 2022
A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics.
Pennitz, P. ORCID: https://orcid.org/0000-0002-8132-7237, Kirsten, H., Friedrich, V.D., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Goekeri, C. ORCID: https://orcid.org/0000-0002-1616-4005, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Heinz, G.A., Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Büttner, M., Trimpert, J., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Suttorp, N., Hocke, A.C., Hippenstiel, S., Tönnies, M., Scholz, M., Kuebler, W.M., Witzenrath, M., Hoenzke, K. and Nouailles, G. ORCID: https://orcid.org/0000-0003-1973-3119
European Respiratory Review 31
(165): 220056.
30 September 2022
Treatment with ribociclib shows favourable immunomodulatory effects in patients with hormone receptor-positive breast cancer-findings from the RIBECCA trial.
Peuker, C.A. ORCID: https://orcid.org/0000-0002-0957-2166, Yaghobramzi, S., Grunert, C. ORCID: https://orcid.org/0000-0001-8376-8629, Keilholz, L, Gjerga, E., Hennig, S., Schaper, S., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Brucker, S. ORCID: https://orcid.org/0000-0001-5162-1542, Decker, T., Fasching, P., Fehm, T., Janni, W., Kümmel, S. ORCID: https://orcid.org/0000-0001-9355-494X, Schneeweiss, A., Schuler, M. ORCID: https://orcid.org/0000-0002-2166-3394, Lüftner, D. ORCID: https://orcid.org/0000-0003-2511-9115 and Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947
European Journal of Cancer 162
: 45-55.
February 2022
A RAS-independent biomarker panel to reliably predict response to MEK inhibition in colorectal cancer.
Pfohl, U., Loskutov, J., Bashir, S. ORCID: https://orcid.org/0000-0002-1281-8710, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Herter, P. ORCID: https://orcid.org/0000-0002-2340-2171, Templin, M., Mamlouk, S. ORCID: https://orcid.org/0000-0001-7285-1320, Belanov, S. ORCID: https://orcid.org/0000-0003-3419-3659, Linnebacher, M. ORCID: https://orcid.org/0000-0001-8054-1402, Bürtin, F., Vetter, M., Reinhard, C., Wedeken, L. ORCID: https://orcid.org/0000-0003-1061-9459 and Regenbrecht, C.R.A. ORCID: https://orcid.org/0000-0001-9494-5977
Cancers 14
(13): 3252.
1 July 2022
Engineering, decoding and systems-level characterization of chimpanzee cytomegalovirus.
Phan, Q.V., Bogdanow, B. ORCID: https://orcid.org/0000-0002-9634-7353, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Liu, F., Hagemeier, C. and Wiebusch, L. ORCID: https://orcid.org/0000-0002-7210-6731
PLoS Pathogens 18
(1): e1010193.
4 January 2022
Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.
Poetz, F., Lebedeva, S. ORCID: https://orcid.org/0000-0003-0857-8256, Schott, J., Lindner, D., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Stoecklin, G. ORCID: https://orcid.org/0000-0001-9284-9834
Genome Biology 23
(1): 193.
12 September 2022
Antigen receptor-engineered Tregs inhibit CNS autoimmunity in cell therapy using non-redundant immune mechanisms in mice.
Pohar, J. ORCID: https://orcid.org/0000-0002-7616-164X, O'Connor, R., Manfroi, B., Behi, M.E., Jouneau, L., Boudinot, P., Bunse, M. ORCID: https://orcid.org/0000-0002-7554-2520, Uckert, W., Luka, M., Ménager, M., Liblau, R., Anderton, S.M. and Fillatreau, S. ORCID: https://orcid.org/0000-0002-7730-9917
European Journal of Immunology 52
(8): 1335-1349.
August 2022
The role of CD4 T cells in rejection of solid tumors.
Poncette, L. ORCID: https://orcid.org/0000-0001-8300-3968, Bluhm, J. and Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321
Current Opinion in Immunology 74
: 18-24.
February 2022
Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders.
Porubsky, D., Höps, W., Ashraf, H., Hsieh, P.H., Rodriguez-Martin, B., Yilmaz, F., Ebler, J., Hallast, P., Maggiolini, F.A.M., Harvey, W.T., Henning, B., Audano, P.A., Gordon, D.S., Ebert, P., Hasenfeld, P., Benito, E., Zhu, Q., Lee, C., Antonacci, F., Steinrücken, M., Beck, C.R., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Marschall, T., Eichler, E.E. and Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794
Cell 185
(11): 1986-2005.
26 May 2022
Long-term imaging reveals behavioral plasticity during C. elegans dauer exit.
Preusser, F. ORCID: https://orcid.org/0000-0001-8231-2195, Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Preibisch, S. ORCID: https://orcid.org/0000-0002-0276-494X
BMC Biology 20
(1): 277.
13 December 2022
Targeting Wnt/β-catenin signaling by TET1/FOXO4 inhibits metastatic spreading and self-renewal of cancer stem cells in gastric cancer.
Qi, J., Cui, D., Wu, Q.N., Zhao, Q. ORCID: https://orcid.org/0000-0002-8683-6145, Chen, Z.H., Li, L., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Yu, Y. and Tao, R.
Cancers 14
(13): 3232.
30 June 2022
The genomic and transcriptional landscape of primary central nervous system lymphoma.
Radke, J. ORCID: https://orcid.org/0000-0001-9860-2007, Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X, Koll, R., Gu, Z., Schumann, E., Sieverling, L. ORCID: https://orcid.org/0000-0002-0595-4976, Uhrig, S., Hübschmann, D. ORCID: https://orcid.org/0000-0002-6041-7049, Toprak, U.H., López, C., Hostench, X.P. ORCID: https://orcid.org/0000-0003-2089-3777, Borgoni, S., Juraeva, D. ORCID: https://orcid.org/0000-0003-0035-3503, Pritsch, F., Paramasivam, N., Balasubramanian, G.P., Schlesner, M. ORCID: https://orcid.org/0000-0002-5896-4086, Sahay, S., Weniger, M., Pehl, D., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Osterloh, A., Korfel, A., Misch, M., Onken, J., Faust, K., Vajkoczy, P., Moskopp, D. ORCID: https://orcid.org/0000-0002-4173-7653, Wang, Y., Jödicke, A., Trümper, L., Anagnostopoulos, I., Lenze, D., Küppers, R. ORCID: https://orcid.org/0000-0002-6691-7191, Hummel, M., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Wiestler, O.D., Wolf, S., Unterberg, A., Eils, R. ORCID: https://orcid.org/0000-0002-0034-4036, Herold-Mende, C., Brors, B. ORCID: https://orcid.org/0000-0001-5940-3101, Siebert, R., Wiemann, S. ORCID: https://orcid.org/0000-0003-4683-3174 and Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917
Nature Communications 13
(1): 2558.
10 May 2022
Cellular hierarchies predict drug response in acute myeloid leukemia.
Raffel, S., Velten, L. and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Cancer Cell 40
(9): 917-919.
12 September 2022
FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer.
Raschzok, N., Stintzing, S., Heinemann, V., Rauch, G., Ricke, J., Guckenberger, M., Kurreck, A., Alig, A.H.S., Stahler, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schmelzle, M., Schöning, W., Lurje, G., Krenzien, F., Haase, O., Rau, B., Gebauer, B., Sauer, I.M., Pratschke, J. and Modest, D.P.
BMC Cancer 22
(1): 359.
2 April 2022
A novel gene controls a new structure: piggyBac transposable element-derived 1, unique to mammals, controls mammal-specific neuronal paraspeckles.
Raskó, T., Pande, A. ORCID: https://orcid.org/0009-0008-0826-973X, Radscheit, K., Zink, A. ORCID: https://orcid.org/0000-0002-8489-6339, Singh, M. ORCID: https://orcid.org/0000-0002-8626-5418, Sommer, C., Wachtl, G., Kolacsek, O., Inak, G., Szvetnik, A., Petrakis, S., Bunse, M. ORCID: https://orcid.org/0000-0002-7554-2520, Bansal, V. ORCID: https://orcid.org/0000-0002-0944-7226, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Orbán, T.I., Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952, Hurst, L.D. ORCID: https://orcid.org/0000-0002-1002-1054 and Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384
Molecular Biology and Evolution 39
(10): msac175.
October 2022
Intricacies of single-cell multi-omics data integration.
Rautenstrauch, P. ORCID: https://orcid.org/0000-0002-0070-4759, Vlot, A.H.C. ORCID: https://orcid.org/0000-0001-9538-987X, Saran, S. ORCID: https://orcid.org/0009-0001-0561-6328 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Trends in Genetics 38
(2): 128-139.
February 2022
EBAG9 controls CD8(+) T cell memory formation responding to tumor challenge in mice.
Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950, Wirges, A. ORCID: https://orcid.org/0000-0001-7038-4503, Hoser, D., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Herda, S., Gerlach, K., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X and Hoepken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893
JCI Insight 7
(11): e155534.
8 June 2022
Comparison of FACS and PCR for detection of BCMA-CAR-T cells.
Reichman, A., Kunz, A., Joedicke, J.J. ORCID: https://orcid.org/0000-0002-4708-3216, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Keib, A., Neuber, B., Sedloev, D., Wang, L., Jiang, G., Hückelhoven-Krauss, A., Eberhardt, F., Müller-Tidow, C., Wermke, M., Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950, Schmitt, M. ORCID: https://orcid.org/0000-0002-1579-1509 and Schmitt, A.
International Journal of Molecular Sciences 23
(2): 903.
14 January 2022
The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL.
Rejeski, K. ORCID: https://orcid.org/0000-0003-3905-0251, Perez, A., Iacoboni, G., Penack, O., Bücklein, V., Jentzsch, L., Mougiakakos, D., Johnson, G., Arciola, B., Carpio, C., Blumenberg, V., Hoster, E., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Locke, F.L., von Bergwelt-Baildon, M., Mackensen, A., Bethge, W., Barba, P., Jain, M.D. ORCID: https://orcid.org/0000-0002-7789-1257 and Subklewe, M.
Journal for ImmunoTherapy of Cancer 10
(5): e004475.
17 May 2022
TCR gene therapy for cancer.
Rhein, S. ORCID: https://orcid.org/0000-0002-9445-2352 and Çakmak-Görür, N. ORCID: https://orcid.org/0000-0001-7857-2461
Methods in Molecular Biology 2521
(3): 95-128.
23 June 2022
90-yttrium-ibritumomab tiuxetan as first-line treatment for follicular lymphoma: updated efficacy and safety results at an extended median follow-up of 9.6 years.
Rieger, K. ORCID: https://orcid.org/0000-0002-2754-8581, De Filippi, R., Lindén, O., Viardot, A., Hess, G., Lerch, K., Neumeister, P., Stroux, A., Peuker, C.A. ORCID: https://orcid.org/0000-0002-0957-2166, Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470, Pinto, A., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Scholz, C.W.
Annals of Hematology 101
(4): 781-788.
April 2022
Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes.
Ringel, A.R. ORCID: https://orcid.org/0000-0002-6392-6076, Szabo, Q. ORCID: https://orcid.org/0000-0002-3539-7875, Chiariello, A.M. ORCID: https://orcid.org/0000-0002-6112-0167, Chudzik, K. ORCID: https://orcid.org/0000-0002-7606-8381, Schöpflin, R., Rothe, P. ORCID: https://orcid.org/0000-0003-2366-7775, Mattei, A.L. ORCID: https://orcid.org/0000-0003-1450-8924, Zehnder, T., Harnett, D. ORCID: https://orcid.org/0000-0002-9190-128X, Laupert, V., Bianco, S. ORCID: https://orcid.org/0000-0001-5819-060X, Hetzel, S. ORCID: https://orcid.org/0000-0002-4783-3814, Glaser, J., Phan, M.H.Q., Schindler, M. ORCID: https://orcid.org/0000-0003-3363-1864, Ibrahim, D.M. ORCID: https://orcid.org/0000-0002-0019-3354, Paliou, C., Esposito, A. ORCID: https://orcid.org/0000-0002-5903-8439, Prada-Medina, C.A., Haas, S.A., Giere, P. ORCID: https://orcid.org/0000-0002-5570-0085, Vingron, M., Wittler, L. ORCID: https://orcid.org/0000-0001-7873-6702, Meissner, A., Nicodemi, M. ORCID: https://orcid.org/0000-0002-8416-6416, Cavalli, G. ORCID: https://orcid.org/0000-0003-3709-3469, Bantignies, F., Mundlos, S. and Robson, M.I. ORCID: https://orcid.org/0000-0003-1126-3538
Cell 185
(20): 3689-3704.
29 September 2022
JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia.
Rosenberg, J.M., Peters, J.M., Hughes, T., Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Massoth, L.R., Austin-Tse, C., Rehm, H.L., Bryson, B., Chen, Y.B., Regev, A., Shalek, A.K., Fortune, S.M. and Sykes, D.B.
Med 3
(1): 42-57.e5.
14 January 2022
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants.
Rothenberger, S. ORCID: https://orcid.org/0000-0001-8633-2994, Hurdiss, D.L., Walser, M., Malvezzi, F., Mayor, J., Ryter, S., Moreno, H., Liechti, N. ORCID: https://orcid.org/0000-0003-4354-2419, Bosshart, A., Iss, C., Calabro, V., Cornelius, A., Hospodarsch, T., Neculcea, A., Looser, T., Schlegel, A., Fontaine, S., Villemagne, D. ORCID: https://orcid.org/0000-0002-4465-364X, Paladino, M., Schiegg, D., Mangold, S., Reichen, C., Radom, F., Kaufmann, Y., Schaible, D., Schlegel, I., Zitt, C., Sigrist, G., Straumann, M., Wolter, J., Comby, M., Sacarcelik, F., Drulyte, I., Lyoo, H. ORCID: https://orcid.org/0000-0001-5806-9463, Wang, C., Li, W., Du, W., Binz, H.K. ORCID: https://orcid.org/0000-0003-0702-2280, Herrup, R., Lusvarghi, S. ORCID: https://orcid.org/0000-0003-1793-0450, Neerukonda, S.N., Vassell, R., Wang, W., Adler, J.M. ORCID: https://orcid.org/0000-0001-8147-0351, Eschke, K., Nascimento, M., Abdelgawad, A., Gruber, A.D., Bushe, J. ORCID: https://orcid.org/0000-0001-6103-3277, Kershaw, O., Knutson, C.G., Balavenkatraman, K.K., Ramanathan, K., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Lewis, S., Watson, R., Haeuptle, M.A., Zürcher, A., Dawson, K.M. ORCID: https://orcid.org/0000-0002-1770-291X, Steiner, D., Weiss, C.D. ORCID: https://orcid.org/0000-0002-9965-1289, Amstutz, P., van Kuppeveld, F.J.M., Stumpp, M.T. ORCID: https://orcid.org/0000-0001-7356-2061, Bosch, B.J. ORCID: https://orcid.org/0000-0002-3864-232X, Engler, O. ORCID: https://orcid.org/0000-0002-8404-1496 and Trimpert, J. ORCID: https://orcid.org/0000-0003-1616-0810
Nature Biotechnology 40
(12): 1845-1854.
December 2022
CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Rousselle, A. ORCID: https://orcid.org/0000-0002-0641-3143, Sonnemann, J. ORCID: https://orcid.org/0000-0002-6513-7775, Amann, K., Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427, Lodka, D. ORCID: https://orcid.org/0009-0009-3317-6487, Kling, L. ORCID: https://orcid.org/0000-0001-7894-6187, Bieringer, M., Schneider, U. ORCID: https://orcid.org/0000-0002-9117-3307, Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X, Enghard, P. ORCID: https://orcid.org/0000-0002-7254-3931, Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718 and Schreiber, A. ORCID: https://orcid.org/0000-0003-1244-6379
Annals of the Rheumatic Diseases 81
(8): 1162-1172.
August 2022
Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
Rücker, F.G., Du, L., Luck, T.J., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Krzykalla, J., Gathmann, I., Voso, M.T. ORCID: https://orcid.org/0000-0002-6164-4761, Amadori, S., Prior, T.W., Brandwein, J.M., Appelbaum, F.R., Medeiros, B.C. ORCID: https://orcid.org/0000-0001-6972-8137, Tallman, M.S., Savoie, L., Sierra, J., Pallaud, C., Sanz, M.A. ORCID: https://orcid.org/0000-0003-1489-1177, Jansen, J.H., Niederwieser, D. ORCID: https://orcid.org/0000-0002-4737-1103, Fischer, T., Ehninger, G., Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Ganser, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Larson, R.A. ORCID: https://orcid.org/0000-0001-9168-3203, Bloomfield, C.D. ORCID: https://orcid.org/0000-0001-5465-7591, Stone, R.M., Döhner, H., Thiede, C. ORCID: https://orcid.org/0000-0003-1241-2048 and Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862
Leukemia 36
(1): 90-99.
January 2022
Clonal expansion and epigenetic inheritance of long-lasting NK cell memory.
Rückert, T. ORCID: https://orcid.org/0000-0003-1433-1372, Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Mashreghi, M.F. ORCID: https://orcid.org/0000-0002-8015-6907, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164 and Romagnani, C. ORCID: https://orcid.org/0000-0002-5167-7463
Nature Immunology 23
(11): 1551-1563.
November 2022
KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in Plasmodium falciparum-infected erythrocytes.
Sanchez, C.P. ORCID: https://orcid.org/0000-0002-3334-3726, Patra, P. ORCID: https://orcid.org/0000-0002-2275-3738, Chang, S.Y.S. ORCID: https://orcid.org/0000-0002-5627-9106, Karathanasis, C. ORCID: https://orcid.org/0000-0002-1333-2341, Hanebutte, L. ORCID: https://orcid.org/0000-0001-5911-0763, Kilian, N. ORCID: https://orcid.org/0000-0001-7489-9782, Cyrklaff, M., Heilemann, M. ORCID: https://orcid.org/0000-0002-9821-3578, Schwarz, U.S. ORCID: https://orcid.org/0000-0003-1483-640X, Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274 and Lanzer, M. ORCID: https://orcid.org/0000-0002-0220-6526
Molecular Microbiology 117
(2): 274-292.
February 2022
Identification of environmental factors that promote intestinal inflammation.
Sanmarco, L.M., Chao, C.C. ORCID: https://orcid.org/0000-0003-4108-2658, Wang, Y.C. ORCID: https://orcid.org/0000-0002-1574-1691, Kenison, J.E., Li, Z. ORCID: https://orcid.org/0000-0002-5268-6986, Rone, J.M., Rejano-Gordillo, C.M. ORCID: https://orcid.org/0000-0003-4586-5975, Polonio, C.M. ORCID: https://orcid.org/0000-0003-0460-0161, Gutierrez-Vazquez, C. ORCID: https://orcid.org/0000-0002-3846-4631, Piester, G. ORCID: https://orcid.org/0000-0001-8413-7298, Plasencia, A. ORCID: https://orcid.org/0000-0002-7415-0947, Li, L., Giovannoni, F., Lee, H.G. ORCID: https://orcid.org/0000-0001-5960-5504, Faust Akl, C., Wheeler, M.A. ORCID: https://orcid.org/0000-0002-0689-6384, Mascanfroni, I., Jaronen, M., Alsuwailm, M., Hewson, P., Yeste, A., Andersen, B.M., Franks, D.G., Huang, C.J., Ekwudo, M., Tjon, E.C., Rothhammer, V., Takenaka, M., de Lima, K.A., Linnerbauer, M. ORCID: https://orcid.org/0000-0002-5528-5141, Guo, L., Covacu, R. ORCID: https://orcid.org/0000-0003-3183-2988, Queva, H., Fonseca-Castro, P.H., Bladi, M.A., Cox, L.M. ORCID: https://orcid.org/0000-0002-9564-9894, Hodgetts, K.J., Hahn, M.E. ORCID: https://orcid.org/0000-0003-4358-2082, Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427, Korzenik, J. ORCID: https://orcid.org/0000-0001-7692-5710, Hauser, R., Snapper, S.B. ORCID: https://orcid.org/0000-0003-0267-4247 and Quintana, F.J. ORCID: https://orcid.org/0000-0001-8156-0736
Nature 611
(7937): 801-809.
24 November 2022
A knowledge graph to interpret clinical proteomics data.
Santos, A. ORCID: https://orcid.org/0000-0002-9163-7730, Colaço, A.R., Nielsen, A.B., Niu, L., Strauss, M., Geyer, P.E., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Albrechtsen, N.J.W. ORCID: https://orcid.org/0000-0003-4230-5753, Mundt, F., Jensen, L.J. ORCID: https://orcid.org/0000-0001-7885-715X and Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799
Nature Biotechnology 40
(5): 692-702.
22 May 2022
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Zhang, L., Maurer, S., Maurer, H.C., Isaakaidis, K., Schneider, L., Patra, U., Schunck, K., Rohleder, E., Hofstetter, J. ORCID: https://orcid.org/0000-0003-4496-2394, Baluapuri, A. ORCID: https://orcid.org/0000-0002-3723-7891, Scherger, A.K., Slotta-Huspenina, J., Hettler, F., Weber, J. ORCID: https://orcid.org/0000-0002-0183-8994, Engleitner, T., Maresch, R. ORCID: https://orcid.org/0000-0003-3393-8882, Slawska, J., Lewis, R. ORCID: https://orcid.org/0000-0002-2404-6703, Istvanffy, R., Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Steiger, K. ORCID: https://orcid.org/0000-0002-7269-5433, Baiker, A., Oostendorp, R.A.J. ORCID: https://orcid.org/0000-0002-4947-0412, Miething, C. ORCID: https://orcid.org/0000-0003-4699-3805, Lenhof, H.P., Bassermann, F., Chapuy, B. ORCID: https://orcid.org/0000-0002-6485-8773, Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Wolf, E. ORCID: https://orcid.org/0000-0002-5299-6335, Rad, R. ORCID: https://orcid.org/0000-0002-6849-9659, Müller, S. and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Nature Communications 13
(1): 281.
12 January 2022
Capillary gel electrophoresis (CGE) for quality control of plasmid DNA in gene therapy: quality control of 20 years stored GMP-grade plasmid DNA.
Schmeer, M., Schleef, M., Shankar, R., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648 and Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231
Methods in Molecular Biology 2521
(3): 317-328.
23 June 2022
Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker.
Schmid, F., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Röhrich, H., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Hoffmann, J. ORCID: https://orcid.org/0000-0003-3880-1658, Burock, S., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
British Journal of Cancer 127
(4): 675-685.
1 September 2022
B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
Schmid, V.K., Khadour, A., Ahmed, N., Brandl, C., Nitschke, L., Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Jumaa, H. and Hobeika, E.
Haematologica 107
(8): 1796-1814.
August 2022
Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
Schmiester, M., Maier, R., Riedel, R., Durek, P., Frentsch, M., Kolling, S., Mashreghi, M.F., Jenq, R., Zhang, L., Peterson, C.B. ORCID: https://orcid.org/0000-0003-3316-0468, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Chang, H.D. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Gut Microbes 14
(1): e2081475.
29 May 2022
Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.
Schmiester, M. ORCID: https://orcid.org/0000-0002-8713-572X, Tranter, E., Lorusso, A., Blaschke, F. ORCID: https://orcid.org/0000-0001-7193-0318, Geisel, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Damm, F. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
BMC Cardiovascular Disorders 22
(1): 31.
4 February 2022
COVID-19: new disease mechanism is simultaneously a therapeutic target.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
memo: Magazine of European Medical Oncology 15
(2): 100-101.
June 2022
Senescence and cancer - role and therapeutic opportunities.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Wang, B. and Demaria, M.
Nature Reviews Clinical oncology 19
(10): 619–636.
October 2022
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M., Schwarzer, A., Jayavelu, A.K., Hsu, C.J., Kirkpatrick, J. ORCID: https://orcid.org/0000-0001-9291-7294, Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S.A. ORCID: https://orcid.org/0000-0001-5634-1347, Nafria, M. ORCID: https://orcid.org/0000-0002-5329-7966, Jiang, L., Dai, Y.T. ORCID: https://orcid.org/0000-0001-8275-2115, Chen, Z., Chen, S.J., Kellaway, S.G. ORCID: https://orcid.org/0000-0002-4011-7460, Ptasinska, A., Ng, E.S. ORCID: https://orcid.org/0000-0002-7970-8129, Stanley, E.G., Elefanty, A.G. ORCID: https://orcid.org/0000-0001-6448-8314, Buschbeck, M., Bierhoff, H., Brodt, S. ORCID: https://orcid.org/0000-0003-1286-8766, Matziolis, G., Fischer, K.D., Hochhaus, A., Chen, C.W. ORCID: https://orcid.org/0000-0002-8737-6830, Heidenreich, O. ORCID: https://orcid.org/0000-0001-5404-6483, Mann, M., Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Ori, A. ORCID: https://orcid.org/0000-0002-3046-0871, von Eyss, B. ORCID: https://orcid.org/0000-0002-4731-6841, Bonifer, C. and Heidel, F. ORCID: https://orcid.org/0000-0003-2438-1955
Blood 139
(7): 1080-1097.
17 February 2022
Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours.
Schubert, N.A., Chen, C.Y., Rodríguez, A., Koster, J., Dowless, M., Pfister, S.M., Shields, D.J., Stancato, L.F., Vassal, G., Caron, H.N., van den Boogaard, M.L., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X and Molenaar, J.J.
European Journal of Cancer 170
: 196-208.
July 2022
Helicobacter pylori - neue Aspekte kommender Leitlinien [Helicobacter pylori - new aspects of forthcoming guidelines].
Schulz, C., Fischbach, W., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Schütte, K., Suerbaum, S. and Malfertheiner, P.
Internist 63
(4): 367-371.
1 March 2022
Evidence of neural crest cell origin of a DICER1 mutant CNS sarcoma in a child with DICER1 syndrome and NRAS-mutant neurocutaneous melanosis.
Schweizer, L. ORCID: https://orcid.org/0000-0002-4649-2587, Hartmann, W., Koch, A., Nunninger, M., Thomale, U.W., Pennacchietti, V., Tietze, A., Horn, D., Pajtler, K.W., Hirsch, S., Wieland, I., Deubzer, H. ORCID: https://orcid.org/0000-0002-6115-4893, Rossi, R., Hernáiz Driever, P., von Hoff, K. and von Zezschwitz, B.
Neuropathology and Applied Neurobiology 48
(6): e12830.
October 2022
A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants.
Shahan, R., Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Nolan, T.M., Cole, B.J., Taylor, I.W., Greenstreet, L., Zhang, S., Afanassiev, A., Vlot, A.H.C. ORCID: https://orcid.org/0000-0001-9538-987X, Schiebinger, G., Benfey, P.N. and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Developmental Cell 57
(4): 543-560.
28 February 2022
K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.
Shearer, R.F. ORCID: https://orcid.org/0000-0003-3012-8788, Typas, D. ORCID: https://orcid.org/0000-0002-8737-1319, Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Schovsbo, S. ORCID: https://orcid.org/0000-0002-7173-0911, Kruse, T. ORCID: https://orcid.org/0000-0002-2619-7388, Mund, A. ORCID: https://orcid.org/0000-0002-7843-5341 and Mailand, N. ORCID: https://orcid.org/0000-0002-6623-709X
EMBO Journal 41
(9): e110145.
2 May 2022
Graph neural networks for learning molecular excitation spectra.
Singh, K. ORCID: https://orcid.org/0000-0003-2700-9307, Münchmeyer, J., Weber, L. ORCID: https://orcid.org/0000-0002-2499-472X, Leser, U. and Bande, A. ORCID: https://orcid.org/0000-0003-3827-9169
Journal of Chemical Theory and Computation 18
(7): 4408-4417.
12 July 2022
A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish.
Singh, S.P. ORCID: https://orcid.org/0000-0002-5154-3318, Chawla, P., Hnatiuk, A., Kamel, M., Silva, L.D., Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Eski, S.E., Janjuha, S., Olivares-Chauvet, P., Kayisoglu, O., Rost, F., Bläsche, J., Kränkel, A., Petzold, A., Kurth, T., Reinhardt, S., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Ninov, N. ORCID: https://orcid.org/0000-0003-3286-6100
Development 149
(2): dev199853.
January 2022
Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy.
Sinha Ray, S., Dutta, D., Dennys, C., Powers, S., Roussel, F., Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072, Glažar, P. ORCID: https://orcid.org/0000-0003-0842-0088, Zhang, X., Biswas, P., Caporale, J.R., Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Bickle, M., Wein, N., Bellen, H.J., Likhite, S., Marcogliese, P.C. and Meyer, K.C. ORCID: https://orcid.org/0000-0002-5052-2101
Cell Reports 41
(10): 111751.
6 December 2022
CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment.
Skroblyn, T. ORCID: https://orcid.org/0000-0002-4281-9087, Joedicke, J.J. ORCID: https://orcid.org/0000-0002-4708-3216, Pfau, M., Krüger, K., Bourquin, J.P. ORCID: https://orcid.org/0000-0001-6571-6227, Izraeli, S. ORCID: https://orcid.org/0000-0002-6938-2540, Eckert, C. and Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893
Journal of Pathology 258
(1): 12-25.
September 2022
Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
Specker, E. ORCID: https://orcid.org/0000-0002-9471-9520, Matthes, S., Wesolowski, R. ORCID: https://orcid.org/0009-0002-7228-1051, Schütz, A. ORCID: https://orcid.org/0000-0002-0606-2574, Grohmann, M., Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Pleimes, D., Mallow, K., Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, Gogolin, A., Weise, M., Pfeifer, J., Ziebart, N., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330 and Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164
Journal of Medicinal Chemistry 65
(16): 11126-11149.
25 August 2022
Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas.
Staudacher, J.J. ORCID: https://orcid.org/0000-0001-5697-2798, Arnold, A., Kühl, A.A., Pötzsch, M., Daum, S., Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773
BMC Cancer 22
(1): 953.
5 September 2022
DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M., Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancers 14
(6): 1453.
11 March 2022
Editorial: Mitochondria as a hub in cellular signaling.
Stoolman, J.S., Porcelli, A.M. and Martínez-Reyes, I. ORCID: https://orcid.org/0000-0003-0479-1535
Frontiers in Cell and Developmental Biology 10
: 981464.
15 August 2022
Comorbidities rather than older age define outcome in adult patients with tumors of the Ewing sarcoma family.
Striefler, J.K. ORCID: https://orcid.org/0000-0002-0612-3023, Schmiester, M., Brandes, F., Dörr, A., Pahl, S., Kaul, D., Rau, D., Dobrindt, E.M., Koulaxouzidis, G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Märdian, S. and Flörcken, A.
Cancer Medicine 11
(17): 3213-3225.
September 2022
MCT1 is a predictive marker for lenalidomide maintenance therapy in multiple myeloma.
Stroh, J., Seckinger, A. ORCID: https://orcid.org/0000-0002-2771-712X, Heider, M., Rudelius, M., Eichner, R. ORCID: https://orcid.org/0000-0002-8433-9452, Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Slawska, J., Emde, M., Salwender, H., Bertsch, U., Goldschmidt, H. ORCID: https://orcid.org/0000-0003-0961-0035, Weisel, K.C., Scheid, C., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Hose, D. and Bassermann, F.
Blood Advances 6
(2): 515-520.
25 January 2022
Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
Subramanian, S. ORCID: https://orcid.org/0000-0002-4917-084X, Busch, C.J.L., Molawi, K., Geirsdottir, L., Maurizio, J., Vargas Aguilar, S., Belahbib, H., Gimenez, G., Yuda, R.A.A., Burkon, M., Favret, J., Gholamhosseinian Najjar, S. ORCID: https://orcid.org/0000-0001-8457-2564, de Laval, B., Kandalla, P.K., Sarrazin, S., Alexopoulou, L. ORCID: https://orcid.org/0000-0003-4619-697X and Sieweke, M.H. ORCID: https://orcid.org/0000-0002-3228-9537
Nature Immunology 23
(3): 458-468.
March 2022
The landscape of genetic aberrations in myxofibrosarcoma.
Takeuchi, Y., Yoshida, K., Halik, A., Kunitz, A., Suzuki, H., Kakiuchi, N., Shiozawa, Y., Yokoyama, A., Inoue, Y., Hirano, T., Yoshizato, T., Aoki, K., Fujii, Y., Nannya, Y., Makishima, H., Pfitzner, B.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Hirata, M., Jinnouchi, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Okamoto, T., Haga, H., Ogawa, S. and Damm, F. ORCID: https://orcid.org/0000-0001-5553-1173
International Journal of Cancer 151
(4): 565-577.
15 August 2022
Concomitant cytotoxic effector differentiation of CD4(+) and CD8(+) T cells in response to EBV-Infected B cells.
Tamura, Y., Yamane, K., Kawano, Y., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wirtz, T. ORCID: https://orcid.org/0009-0005-5677-9804, Weber, T. ORCID: https://orcid.org/0000-0003-2079-842X, Sander, S. ORCID: https://orcid.org/0000-0003-4645-3366, Ohki, S., Kitajima, Y. ORCID: https://orcid.org/0000-0001-6277-5918, Okada, S. ORCID: https://orcid.org/0000-0002-4622-5657, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Yasuda, T. ORCID: https://orcid.org/0000-0001-9997-6852
Cancers 14
(17): 4118.
25 August 2022
Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi, Y. ORCID: https://orcid.org/0000-0002-1595-9631, Arango-Ossa, J.E., Zhou, Y., Bernard, E. ORCID: https://orcid.org/0000-0002-2057-7187, Thomas, I., Gilkes, A., Freeman, S. ORCID: https://orcid.org/0000-0003-1869-180X, Pradat, Y. ORCID: https://orcid.org/0000-0002-4647-5779, Johnson, S.J., Hills, R., Dillon, R., Levine, M.F. ORCID: https://orcid.org/0000-0001-5156-9086, Leongamornlert, D. ORCID: https://orcid.org/0000-0002-3486-3168, Butler, A., Ganser, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862, Ottmann, O., Adams, R. ORCID: https://orcid.org/0000-0003-3915-7243, Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536, Campbell, P.J. ORCID: https://orcid.org/0000-0002-3921-0510, Burnett, A.K. ORCID: https://orcid.org/0000-0003-1734-5817, Dennis, M., Russell, N.H., Devlin, S.M. ORCID: https://orcid.org/0000-0002-6801-720X, Huntly, B.J.P. ORCID: https://orcid.org/0000-0003-0312-161X and Papaemmanuil, E. ORCID: https://orcid.org/0000-0003-1709-8983
Nature Communications 13
(1): 4622.
8 August 2022
Genomic evolution and personalized therapy of an infantile fibrosarcoma harboring an NTRK oncogenic fusion.
Thorwarth, A., Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Röefzaad, C. ORCID: https://orcid.org/0000-0003-2299-6673, Pajtler, K.W. ORCID: https://orcid.org/0000-0002-3562-6121, Schramm, K., Hauptmann, K., Behnke, A. ORCID: https://orcid.org/0000-0003-0629-9587, Vokuhl, C., Elgeti, T. ORCID: https://orcid.org/0000-0002-7155-6044, Gratopp, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Scheer, M., Hernáiz Driever, P., Nysom, K. ORCID: https://orcid.org/0000-0003-2935-0058, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
JCO Precision Oncology 6
: e2100283.
25 May 2022
Precise CRISPR/Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells.
Tran, N.T. ORCID: https://orcid.org/0000-0003-0896-8641, Danner, E. ORCID: https://orcid.org/0000-0003-3277-5727, Li, X. ORCID: https://orcid.org/0000-0002-1173-1066, Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195, de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696
Science Advances 8
(22): eabm9106.
3 June 2022
S100A4 is a strong negative prognostic marker and potential therapeutic target in adenocarcinoma of the stomach and esophagus.
Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773, Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512, Pötzsch, M., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, von Winterfeld, M., Berg, E., Hummel, M., Timm, L., Rau, B. ORCID: https://orcid.org/0000-0001-5820-6907, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Daum, S. ORCID: https://orcid.org/0000-0003-0060-6013, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cells 11
(6): 1056.
21 March 2022
Inhibition of MACC1-induced metastasis in esophageal and gastric adenocarcinomas.
Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773, Werchan, J., von Winterfeld, M., Berg, E., Hummel, M., Timm, L., Rau, B. ORCID: https://orcid.org/0000-0001-5820-6907, Daberkow, O., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Daum, S. ORCID: https://orcid.org/0000-0003-0060-6013, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cancers 14
(7): 1773.
31 March 2022
Cancer stem cells: The adventurous journey from hematopoietic to leukemic stem cells.
Trumpp, A. and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Cell 185
(8): 1266-1270.
14 April 2022
ShapeSorter: a fully probabilistic method for detecting conserved RNA structure features supported by SHAPE evidence.
Tsybulskyi, V. ORCID: https://orcid.org/0009-0002-4141-6291 and Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479
Nucleic Acids Research 50
(15): e85.
26 August 2022
TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation.
Tufan, A.B. ORCID: https://orcid.org/0000-0002-8734-9736, Lazarow, K., Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
EMBO Journal 41
(21): e110372.
2 November 2022
Time-keeping and decision-making in living cells: Part II.
Tyson, J.J. ORCID: https://orcid.org/0000-0001-7560-6013, Csikasz-Nagy, A. ORCID: https://orcid.org/0000-0002-2919-5601, Gonze, D. ORCID: https://orcid.org/0000-0002-9800-2412, Kim, J.K. ORCID: https://orcid.org/0000-0001-7842-2172, Santos, S. ORCID: https://orcid.org/0000-0002-2906-7888 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
Interface Focus 12
(4): 20220024.
10 June 2022
Time-keeping and decision-making in living cells: Part I.
Tyson, J.J. ORCID: https://orcid.org/0000-0001-7560-6013, Csikasz-Nagy, A. ORCID: https://orcid.org/0000-0002-2919-5601, Gonze, D. ORCID: https://orcid.org/0000-0002-9800-2412, Kim, J.K. ORCID: https://orcid.org/0000-0001-7842-2172, Santos, S. ORCID: https://orcid.org/0000-0002-2906-7888 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
Interface Focus 12
(3): 20220011.
6 June 2022
Detection and validation of circular DNA fragments using nanopore sequencing.
Tüns, A.I., Hartmann, T., Magin, S., Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Rahmann, S., Schramm, A. and Köster, J.
Frontiers in Genetics 13
: 867018.
30 May 2022
Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses.
Ventura, P.M.O., Gakovic, M., Fischer, B.A., Spinelli, L. ORCID: https://orcid.org/0000-0002-5801-6297, Rota, G., Pathak, S. ORCID: https://orcid.org/0000-0001-9871-2214, Khameneh, H.J. ORCID: https://orcid.org/0000-0002-1737-0388, Zenobi, A. ORCID: https://orcid.org/0000-0003-2837-7638, Thomson, S., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Cantrell, D.A. and Guarda, G. ORCID: https://orcid.org/0000-0001-9243-6116
EMBO Reports 23
(11): e55399.
7 November 2022
Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507, Dauksaite, V. ORCID: https://orcid.org/0000-0002-9399-4731, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Molecular Cell 82
(11): 2069-2083.
2 June 2022
The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells.
Viñado, A.C., Calvo, I.A. ORCID: https://orcid.org/0000-0001-6619-4571, Cenzano, I. ORCID: https://orcid.org/0000-0002-9030-3069, Olaverri, D. ORCID: https://orcid.org/0000-0003-1740-6616, Cocera, M. ORCID: https://orcid.org/0000-0002-5679-1206, San Martin-Uriz, P., Romero, J.P., Vilas-Zornoza, A., Vera, L., Gomez-Cebrian, N. ORCID: https://orcid.org/0000-0001-5604-9223, Puchades-Carrasco, L. ORCID: https://orcid.org/0000-0003-0340-7458, Lisi-Vega, L.E. ORCID: https://orcid.org/0000-0001-7664-5356, Apaolaza, I. ORCID: https://orcid.org/0000-0002-8961-4513, Valera, P., Guruceaga, E. ORCID: https://orcid.org/0000-0003-0547-681X, Granero-Molto, F. ORCID: https://orcid.org/0000-0003-4817-5232, Ripalda-Cemborain, P. ORCID: https://orcid.org/0000-0001-8425-3563, Luck, T.J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Planes, F.J. ORCID: https://orcid.org/0000-0003-1155-3105, Rifon, J.J., Méndez-Ferrer, S. ORCID: https://orcid.org/0000-0002-9805-9988, Yusuf, R.Z., Pardo-Saganta, A., Prosper, F. ORCID: https://orcid.org/0000-0001-6115-8790 and Saez, B. ORCID: https://orcid.org/0000-0001-7908-7089
Leukemia 36
(8): 1969-1979.
August 2022
Cluster-independent marker feature identification from single-cell omics data using SEMITONES.
Vlot, A.H.C. ORCID: https://orcid.org/0000-0001-9538-987X, Maghsudi, S. and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Nucleic Acids Research 50
(18): e107.
14 October 2022
Elevated MACC1 expression in colorectal cancer is driven by chromosomal instability and is associated with molecular subtype and worse patient survival.
Vuaroqueaux, V. ORCID: https://orcid.org/0000-0001-9120-5332, Musch, A., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Risch, T:, Herrmann, P., Burock, S., Peille, A.L. ORCID: https://orcid.org/0000-0003-0776-6837, Yaspo, M.L., Fiebig, H.H. and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cancers 14
(7): 1749.
1 April 2022
Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection clusters based on integrated genomic surveillance, outbreak analysis and contact tracing in an urban setting.
Walker, A., Houwaart, T., Finzer, P., Ehlkes, L., Tyshaieva, A., Damagnez, M., Strelow, D., Duplessis, A., Nicolai, J., Wienemann, T., Tamayo, T., Kohns Vasconcelos, M., Hülse, L., Hoffmann, K., Lübke, N., Hauka, S., Andree, M., Däumer, M.P., Thielen, A., Kolbe-Busch, S., Göbels, K., Zotz, R., Pfeffer, K., Timm, J. and Dilthey, A.T.
Clinical Infectious Diseases 74
(6): 1039-1046.
15 March 2022
A peculiar case of primary central nervous system T-cell lymphoma with indolent behavior.
Wasilewski, D., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Koch, A., Rosenwald, A., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Vajkoczy, P., Faust, K., Anagnostopoulos, I. and Radke, J. ORCID: https://orcid.org/0000-0001-9860-2007
Acta Neurologica Belgica 123
(2): 667-670.
April 2022
Chemical-protein relation extraction with ensembles of carefully tuned pretrained language models.
Weber, L. ORCID: https://orcid.org/0000-0002-2499-472X, Sänger, M. ORCID: https://orcid.org/0000-0002-2950-2587, Garda, S., Barth, F., Alt, C. and Leser, U.
Database 2022
: baac098.
18 November 2022
Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma.
Welters, C. ORCID: https://orcid.org/0000-0002-3098-9003, Lammoglia Cobo, M.F. ORCID: https://orcid.org/0000-0002-0369-0364, Stein, C.A. ORCID: https://orcid.org/0000-0002-7892-8007, Hsu, M.T. ORCID: https://orcid.org/0000-0002-5862-4305, Ben Hamza, A. ORCID: https://orcid.org/0000-0003-3021-7406, Penter, L. ORCID: https://orcid.org/0000-0002-9060-0207, Chen, X. ORCID: https://orcid.org/0000-0002-5614-1406, Buccitelli, C. ORCID: https://orcid.org/0000-0001-5865-4961, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dietze, K. ORCID: https://orcid.org/0000-0002-8329-8329, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Moosmann, A. ORCID: https://orcid.org/0000-0001-8044-5146, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Gerbitz, A. ORCID: https://orcid.org/0000-0002-0105-2086, Strobel, J. ORCID: https://orcid.org/0000-0002-1117-0350, Hackstein, H. ORCID: https://orcid.org/0000-0001-9722-8180, Rahn, H.P. ORCID: https://orcid.org/0000-0002-5233-3937, Dornmair, K. ORCID: https://orcid.org/0000-0003-0342-5373, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128
Cancer Immunology Research 10
(11): 1407-1419.
1 November 2022
Precision medicine in myeloid malignancies.
Westermann, J. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Seminars in Cancer Biology 84
: 153-169.
September 2022
SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C., Doebele, C., Zindel, A., Lee, K.S. ORCID: https://orcid.org/0000-0001-7682-5736, Rieke, S.A. ORCID: https://orcid.org/0000-0002-2890-1308, Ceribelli, M., Comoglio, F. ORCID: https://orcid.org/0000-0002-8970-6610, Phelan, J.D., Wang, J.Q., Pikman, Y., Jahn, D., Häupl, B., Schneider, C., Scheich, S., Tosto, F.A., Bohnenberger, H. ORCID: https://orcid.org/0000-0003-1038-1030, Stauder, P. ORCID: https://orcid.org/0000-0002-3876-6023, Schnütgen, F. ORCID: https://orcid.org/0000-0002-2426-6685, Slabicki, M., Coulibaly, Z.A., Wolf, S., Bojarczuk, K., Chapuy, B. ORCID: https://orcid.org/0000-0002-6485-8773, Brandts, C.H. ORCID: https://orcid.org/0000-0003-1732-2535, Stroebel, P. ORCID: https://orcid.org/0000-0002-8528-8060, Lewis, C.A., Engelke, M., Xu, X. ORCID: https://orcid.org/0000-0003-1062-2092, Kim, H., Dang, T.H., Schmitz, R. ORCID: https://orcid.org/0000-0002-3348-6807, Hodson, D.J. ORCID: https://orcid.org/0000-0001-6225-2033, Stegmaier, K., Urlaub, H., Serve, H. ORCID: https://orcid.org/0000-0001-8472-5516, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Kreuz, F., Knittel, G. ORCID: https://orcid.org/0000-0001-8395-3701, Rabinowitz, J.D. ORCID: https://orcid.org/0000-0002-1247-4727, Reinhardt, H.C., Vander Heiden, M.G., Thomas, C., Staudt, L.M., Zenz, T. and Oellerich, T. ORCID: https://orcid.org/0000-0001-6570-6125
Blood 139
(4): 538-553.
27 January 2022
Long-term observation of the frequency of secondary colorectal cancer and other malignancies in tyrosine kinase inhibitor treated chronic myeloid leukemia patients and controls.
Winkelmann, N., Schwarz, M., Hildebrandt, B., Henke, O., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Stintzing, S. and le Coutre, P. ORCID: https://orcid.org/0000-0003-4532-1097
eJHaem: The Official Journal of the British Society for Haematology 3
(3): 949-953.
August 2022
EBAG9-silencing exerts an immune checkpoint function without aggravating adverse effects.
Wirges, A. ORCID: https://orcid.org/0000-0001-7038-4503, Bunse, M. ORCID: https://orcid.org/0000-0002-7554-2520, Joedicke, J.J. ORCID: https://orcid.org/0000-0002-4708-3216, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Gudipati, V., Moles, M.W., Shiku, H., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Huppa, J.B., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Molecular Therapy 30
(11): 3358-3378.
2 November 2022
Paired donor and recipient immunophenotyping in allogeneic hematopoietic stem cell transplantation: a cellular network approach.
Wittenbecher, F., Lesch, S., Kolling, S., Blau, I.W., Vuong, L., Borchert, F., Movasshagi, K., Tietze-Bürger, C., Penack, O., Ahn, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Frentsch, M. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 13
: 874499.
23 May 2022
Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.
Wizenty, J. ORCID: https://orcid.org/0000-0003-4261-0416, Müllerke, S., Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Fischer, A.S. ORCID: https://orcid.org/0000-0002-2176-1779, Mollenkopf, H.J., Berger, H., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
EMBO Journal 41
(13): e109996.
4 July 2022
The frequency of differentiated CD3(+)CD27(-)CD28(-) T cells predicts response to CART cell therapy in diffuse large B-cell lymphoma.
Worel, N., Grabmeier-Pfistershammer, K., Kratzer, B., Schlager, M., Tanzmann, A., Rottal, A., Körmöczi, U., Porpaczy, E., Staber, P.B., Skrabs, C., Herkner, H., Gudipati, V., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Salzer, B., Lehner, M., Saxenhuber, N., Friedberg, E., Wohlfarth, P., Hopfinger, G., Rabitsch, W., Simonitsch-Klupp, I., Jäger, U. and Pickl, W.F.
Frontiers in Immunology 13
: 1004703.
9 January 2022
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Wu, Y., Biswas, D., Usaite, I., Angelova, M., Boeing, S., Karasaki, T., Veeriah, S., Czyzewska-Khan, J., Morton, C., Joseph, M., Hessey, S., Reading, J., Georgiou, A., Al-Bakir, M., McGranahan, N., Jamal-Hanjani, M., Hackshaw, A., Quezada, S.A., Hayday, A.C. and Swanton, C.
Nature Cancer 3
(6): 696-709.
June 2022
Radiofrequency electromagnetic fields cause non-temperature-induced physical and biological effects in cancer cells.
Wust, P., Veltsista, P.D., Oberacker, E. ORCID: https://orcid.org/0000-0001-7678-6677, Yavvari, P., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Bengtsson, O., Sterner-Kock, A., Weinhart, M., Heyd, F., Grabowski, P., Stintzing, S. ORCID: https://orcid.org/0000-0002-3297-5801, Heinrich, W. ORCID: https://orcid.org/0000-0001-6113-7375, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Ghadjar, P.
Cancers 14
(21): 5349.
30 October 2022
Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single cell transcriptomics.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Adler, J.M., Eschke, K., Teixeira Alves, G. ORCID: https://orcid.org/0000-0002-5822-4168, Peidli, S. ORCID: https://orcid.org/0000-0002-4257-8690, Pott, F., Kazmierski, J., Michalick, L., Kershaw, O., Bushe, J., Andreotti, S., Pennitz, P., Abdelgawad, A., Postmus, D., Goffinet, C., Kreye, J., Reincke, S.M. ORCID: https://orcid.org/0000-0002-8132-3527, Prüss, H., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Gruber, A.D., Kuebler, W.M., Witzenrath, M., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Nouailles, G. and Trimpert, J. ORCID: https://orcid.org/0000-0003-1616-0810
Molecular Therapy 30
(5): 1952-1965.
4 May 2022
Analysis of copy number variation in men with non-obstructive azoospermia.
Wyrwoll, M.J. ORCID: https://orcid.org/0000-0002-7651-2403, Wabschke, R., Röpke, A., Wöste, M., Ruckert, C., Perrey, S., Rotte, N., Hardy, J., Astica, L., Lupianez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X, Wistuba, J., Westernströer, B., Schlatt, S. ORCID: https://orcid.org/0000-0002-7571-5313, Berman, A.J., Müller, A.M., Kliesch, S. ORCID: https://orcid.org/0000-0002-7561-4870, Yatsenko, A.N. ORCID: https://orcid.org/0000-0002-1690-0172, Tüttelmann, F. and Friedrich, C. ORCID: https://orcid.org/0000-0001-8848-3366
Andrology 10
(8): 1593-1604.
November 2022
Application of precision medicine in clinical routine in haematology - challenges and opportunities.
Wästerlid, T., Cavelier, L., Haferlach, C., Konopleva, M., Fröhling, S., Östling, P., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Fioretos, T. and Smedby, K.E.
Journal of Internal Medicine 292
(2): 243-261.
August 2022
GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y. ORCID: https://orcid.org/0000-0002-8890-2409, Du Jiang, P. ORCID: https://orcid.org/0000-0002-9900-8277, Chao, B.N. ORCID: https://orcid.org/0000-0002-0355-2332, Cagdas, D. ORCID: https://orcid.org/0000-0003-2213-4627, Kubo, S. ORCID: https://orcid.org/0000-0001-9693-9263, Balasubramaniyam, A. ORCID: https://orcid.org/0000-0003-4168-8617, Zhang, Y. ORCID: https://orcid.org/0000-0002-6904-0372, Shadur, B. ORCID: https://orcid.org/0000-0003-0245-894X, NaserEddin, A. ORCID: https://orcid.org/0000-0001-6995-3262, Folio, L.R., Schwarz, B. ORCID: https://orcid.org/0000-0002-5894-953X, Bohrnsen, E. ORCID: https://orcid.org/0000-0003-4327-5242, Zheng, L. ORCID: https://orcid.org/0000-0002-8838-8665, Lynberg, M. ORCID: https://orcid.org/0000-0003-1371-3002, Gottlieb, S. ORCID: https://orcid.org/0000-0003-0550-4761, Leney-Greene, M.A. ORCID: https://orcid.org/0000-0002-3259-1728, Park, A.Y. ORCID: https://orcid.org/0000-0002-0130-1521, Tezcan, I. ORCID: https://orcid.org/0000-0001-7257-4554, Akdogan, A., Gocmen, R. ORCID: https://orcid.org/0000-0002-0223-9336, Onder, S. ORCID: https://orcid.org/0000-0002-5523-0669, Rosenberg, A., Soilleux, E.J. ORCID: https://orcid.org/0000-0002-4032-7249, Johnson, E. ORCID: https://orcid.org/0000-0001-8435-9472, Jackson, P.K. ORCID: https://orcid.org/0000-0002-1742-2539, Demeter, J., Chauvin, S.D. ORCID: https://orcid.org/0000-0003-0232-751X, Paul, F. ORCID: https://orcid.org/0000-0001-5181-3122, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Bulut, H. ORCID: https://orcid.org/0000-0003-0262-6296, Clatworthy, M.R. ORCID: https://orcid.org/0000-0002-3340-9828, Tuong, Z.K. ORCID: https://orcid.org/0000-0002-6735-6808, Zhang, H., Stewart, B.J. ORCID: https://orcid.org/0000-0003-4522-0085, Bosio, C.M. ORCID: https://orcid.org/0000-0002-7332-9611, Stepensky, P. ORCID: https://orcid.org/0000-0002-4923-3660, Clare, S. ORCID: https://orcid.org/0000-0001-9368-6037, Ganesan, S. ORCID: https://orcid.org/0000-0003-1132-2016, Pascall, J.C. ORCID: https://orcid.org/0000-0002-9506-1441, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Butcher, G.W. ORCID: https://orcid.org/0000-0002-3423-7124, McMichael, A.J. ORCID: https://orcid.org/0000-0002-9101-7478, Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995 and Lenardo, M.J. ORCID: https://orcid.org/0000-0003-1584-468X
Journal of Experimental Medicine 219
(6): e20201405.
6 June 2022
Extrachromosomal DNA amplifications in cancer.
Yi, E. ORCID: https://orcid.org/0000-0002-7839-7795, Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X and Verhaak, R.G.W. ORCID: https://orcid.org/0000-0003-2773-0436
Nature Reviews Genetics 23
(12): 760-771.
December 2022
Analysis of single-cell transcriptome data in drosophila.
Yousefian, S. ORCID: https://orcid.org/0000-0003-0902-0369, Musillo, M.J. and Bageritz, J. ORCID: https://orcid.org/0000-0002-9531-0452
Methods in Molecular Biology 2540
(3): 93-111.
19 August 2022
Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.
Zhai, Y., Singh, P., Dolnik, A., Brazda, P., Atlasy, N., Del Gaudio, N., Döhner, K., Döhner, H., Minucci, S., Martens, J., Altucci, L., Megchelenbrink, W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Stunnenberg, H.G.
Molecular Cancer 21
(1): 166.
19 August 2022
HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U. ORCID: https://orcid.org/0000-0002-0782-7751, Milek, M. ORCID: https://orcid.org/0000-0002-0803-8439, Minia, I. ORCID: https://orcid.org/0000-0003-1012-3373, Vieira-Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507, Müller, S., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Hazapis, O.G., Del Giudice, S. ORCID: https://orcid.org/0000-0003-0194-3767, Schwefel, D. ORCID: https://orcid.org/0000-0002-2945-0908, Bley, N., Voigt, F., Chao, J.A. ORCID: https://orcid.org/0000-0002-5895-9156, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Hüttelmaier, S. ORCID: https://orcid.org/0000-0001-9335-4227, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
Nature Communications 13
(1): 2727.
18 May 2022
The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G., Vanzo, R., Amitash, S., Martín-Doncel, E., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Mund, A., Lerdrup, M., Benada, J., Boos, D. and Toledo, L.
Molecular Cell 82
(18): 3350-3365.
15 September 2022
SMOG 2 and OpenSMOG: extending the limits of structure-based models.
de Oliveira, A.B., Contessoto, V.G., Hassan, A., Byju, S., Wang, A., Wang, Y., Dodero-Rojas, E., Mohanty, U., Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Onuchic, J.N. and Whitford, P.C. ORCID: https://orcid.org/0000-0001-7104-2265
Protein Science 31
(1): 158-172.
January 2022
The genomic and spatial mobility of extrachromosomal DNA and its implications for cancer therapy.
van Leen, E. ORCID: https://orcid.org/0000-0001-9545-4803, Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Nature Genetics 54
(2): 107-114.
February 2022
Soluble urokinase plasminogen activator receptor levels are associated with severity of fibrosis in patients with primary sclerosing cholangitis.
Özdirik, B. ORCID: https://orcid.org/0000-0002-8885-737X, Maibier, M., Scherf, M., Nicklaus, J.M., Frohme, J., Puengel, T. ORCID: https://orcid.org/0000-0003-2662-6127, Meyer Zum Büschenfelde, D., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Mueller, T. ORCID: https://orcid.org/0000-0003-3426-5421 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Journal of Clinical Medicine 11
(9): 2479.
28 April 2022
2021
Metastasis : methods and protocols.
Stein, U.S., ed.
Methods in Molecular Biology, 2294
.
Springer / Humana Press, New York, NY.
ISBN 978-1-0716-1349-8
2021
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8(+) T cell responses.
Agerer, B., Koblischke, M., Gudipati, V., Montaño-Gutierrez, L.F., Smyth, M., Popa, A., Genger, J.W., Endler, L., Florian, D.M., Mühlgrabner, V., Graninger, M., Aberle, S.W., Husa, A.M., Shaw, L.E., Lercher, A., Gattinger, P., Torralba-Gombau, R., Trapin, D., Penz, T., Barreca, D., Fae, I., Wenda, S., Traugott, M., Walder, G., Pickl, W.F., Thiel, V., Allerberger, F., Stockinger, H., Puchhammer-Stöckl, E., Weninger, W., Fischer, G., Hoepler, W., Pawelka, E., Zoufaly, A., Valenta, R., Bock, C., Paster, W., Geyeregger, R., Farlik, M., Halbritter, F., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Aberle, J.H. and Bergthaler, A.
Science Immunology 6
(57): eabg6461.
March 2021
From operating table to laboratory bench: the path toward metastasis research from the clinical setting.
Alberto Vilchez, M. ORCID: https://orcid.org/0000-0002-6249-6932 and Rau, B.
Methods in Molecular Biology 2294
: 325-333.
2021
Spontaneous non-sustained ventricular tachycardia and premature ventricular contractions and their prognostic relevance in patients with cancer in routine care.
Albrecht, A., Porthun, J. ORCID: https://orcid.org/0000-0002-4100-4361, Eucker, J., Coats, A.J.S., von Haehling, S., Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470, Karakas, M. ORCID: https://orcid.org/0000-0002-5715-2959, Riess, H., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Landmesser, U., Haverkamp, W., Anker, S.D. and Anker, M.S.
Cancers 13
(10): 2303.
12 May 2021
Functionalized bead assay to measure three-dimensional traction forces during T-cell activation.
Aramesh, M. ORCID: https://orcid.org/0000-0003-2071-1929, Mergenthal, S., Issler, M., Plochberger, B. ORCID: https://orcid.org/0000-0003-2733-9947, Weber, F., Qin, X.H., Liska, R. ORCID: https://orcid.org/0000-0001-7865-1936, Duda, G.N., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Ries, J., Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089 and Klotzsch, E. ORCID: https://orcid.org/0000-0002-7577-9042
Nano Letters 21
(1): 507-514.
13 January 2021
Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect.
Arlt, B. ORCID: https://orcid.org/0000-0002-6665-4037, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Wuenschel, J., Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Journal of Enzyme Inhibition and Medicinal Chemistry 36
(1): 1282-1289.
30 June 2021
Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt, B. ORCID: https://orcid.org/0000-0002-6665-4037, Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Wuenschel, J., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Lodrini, M., Astrahantseff, K., Winkler, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Finkler, S., Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352, Hundsdoerfer, P., Guergen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Hoffmann, J., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Eggert, A., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
International Journal of Cancer 148
(5): 1219-1232.
1 March 2021
Prospective tracking of donor-reactive T-cell clones in the circulation and rejecting human kidney allografts.
Aschauer, C., Jelencsics, K., Hu, K., Heinzel, A., Gregorich, M.G., Vetter, J., Schaller, S., Winkler, S.M., Weinberger, J., Pimenov, L., Gualdoni, G.A., Eder, M., Kainz, A., Troescher, A.R., Regele, H., Reindl-Schwaighofer, R., Wekerle, T., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Sykes, M. and Oberbauer, R.
Frontiers in Immunology 12
: 750005.
14 October 2021
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C., Mouktaroudi, M., Krämer, B., Oestreich, M., Antonakos, N., Nuesch-Germano, M., Gkizeli, K., Bonaguro, L., Reusch, N., Baßler, K., Saridaki, M., Knoll, R., Pecht, T., Kapellos, T.S., Doulou, S., Kröger, C., Herbert, M., Holsten, L., Horne, A. ORCID: https://orcid.org/0000-0002-4209-4573, Gemünd, I.D., Rovina, N., Agrawal, S., Dahm, K., van Uelft, M., Drews, A., Lenkeit, L., Bruse, N., Gerretsen, J., Gierlich, J., Becker, M., Händler, K., Kraut, M., Theis, H., Mengiste, S., Domenico, E., Schulte-Schrepping, J., Seep, L., Raabe, J., Hoffmeister, C., ToVinh, M., Keitel, V., Rieke, G., Talevi, V., Skowasch, D., Aziz, N.A., Pickkers, P., van de Veerdonk, F.L., Netea, M.G., Schultze, J.L., Kox, M., Breteler, M.M.B., Nattermann, J., Koutsoukou, A., Giamarellos-Bourboulis, E.J. and Ulas, T. ORCID: https://orcid.org/0000-0002-9785-4197
Genome Medicine 13
(1): 7.
13 January 2021
Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.
Aslam, M.A. ORCID: https://orcid.org/0000-0003-1905-2583, Alemdehy, M.F. ORCID: https://orcid.org/0000-0002-7936-0652, Kwesi-Maliepaard, E.M. ORCID: https://orcid.org/0000-0001-9658-1935, Muhaimin, F.I., Caganova, M. ORCID: https://orcid.org/0000-0002-4576-6574, Pardieck, I.N., van den Brand, T., van Welsem, T., de Rink, I., Song, J.Y., de Wit, E., Arens, R., Jacobs, H. ORCID: https://orcid.org/0000-0001-6227-9850 and van Leeuwen, F. ORCID: https://orcid.org/0000-0002-7267-7251
EMBO Reports 22
(2): e51184.
3 February 2021
The magnitude of germinal center reactions is restricted by a fixed number of preexisting niches.
Avancena, P., Song, T. ORCID: https://orcid.org/0000-0002-6994-6609, Yao, Y. ORCID: https://orcid.org/0000-0003-4637-9063, Fehlner-Peach, H. ORCID: https://orcid.org/0000-0003-3021-1741, Diamond, B. ORCID: https://orcid.org/0000-0002-3250-3804, Gu, H. ORCID: https://orcid.org/0000-0002-0019-6168, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Zou, Y.R. ORCID: https://orcid.org/0000-0002-3864-8908
Proceedings of the National Academy of Sciences of the United States of America 118
(30): e2100576118.
27 July 2021
CD40 activity on mesenchymal cells negatively regulates OX40L to maintain bone marrow immune homeostasis under stress conditions.
Bassani, B., Tripodo, C., Portararo, P., Gulino, A., Botti, L., Chiodoni, C., Jachetti, E., Bolli, N., Ciciarello, M., Joehrens, K., Anagnostopoulos, I., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Curti, A., Colombo, M.P. and Sangaletti, S.
Frontiers in Immunology 12
: 662048.
18 May 2021
Using DNA sequencing data to quantify T cell fraction and therapy response.
Bentham, R., Litchfield, K., Watkins, T.B.K. ORCID: https://orcid.org/0000-0001-7414-737X, Lim, E.L., Rosenthal, R., Martínez-Ruiz, C., Hiley, C.T., Bakir, M.A., Salgado, R. ORCID: https://orcid.org/0000-0002-1110-3801, Moore, D.A., Jamal-Hanjani, M. ORCID: https://orcid.org/0000-0003-1212-1259, Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018 and McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045
Nature 597
(7877): 555-560.
23 September 2021
Structure of the Yersinia injectisome in intracellular host cell phagosomes revealed by cryo FIB electron tomography.
Berger, C., Ravelli, R.B.G., López-Iglesias, C., Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274, Diepold, A. and Peters, P.J.
Journal of Structural Biology 213
(1): 107701.
March 2021
Skin-resident innate lymphoid cells converge on a pathogenic effector state.
Bielecki, P., Riesenfeld, S.J., Hütter, J.C., Torlai Triglia, E. ORCID: https://orcid.org/0000-0002-6059-0116, Kowalczyk, M.S., Ricardo-Gonzalez, R.R., Lian, M., Amezcua Vesely, M.C., Kroehling, L., Xu, H., Slyper, M., Muus, C., Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Christian, E., Tao, L., Kedaigle, A.J., Steach, H.R., York, A.G., Skadow, M.H., Yaghoubi, P., Dionne, D., Jarret, A., McGee, H.M., Porter, C.B.M., Licona-Limón, P., Bailis, W., Jackson, R., Gagliani, N., Gasteiger, G., Locksley, R.M., Regev, A. and Flavell, R.A.
Nature 592
(7852): 128-132.
1 April 2021
SARS-CoV-2 in humans.
Binder, M. and Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806
Berliner und Munchener Tierarztliche Wochenschrift 134
: 1-13.
30 April 2021
A resource of targeted mutant mouse lines for 5,061 genes.
Birling, M.C., Yoshiki, A. ORCID: https://orcid.org/0000-0002-9450-5151, Adams, D.J. ORCID: https://orcid.org/0000-0001-9490-0306, Ayabe, S. ORCID: https://orcid.org/0000-0003-2737-5315, Beaudet, A.L., Bottomley, J., Bradley, A., Brown, S.D.M., Bürger, A., Bushell, W., Chiani, F. ORCID: https://orcid.org/0000-0002-8887-3900, Chin, H.J.G., Christou, S., Codner, G.F., DeMayo, F.J., Dickinson, M.E., Doe, B., Donahue, L.R., Fray, M.D., Gambadoro, A., Gao, X., Gertsenstein, M., Gomez-Segura, A., Goodwin, L.O., Heaney, J.D., Hérault, Y. ORCID: https://orcid.org/0000-0001-7049-6900, de Angelis, M.H. ORCID: https://orcid.org/0000-0002-7898-2353, Jiang, S.T., Justice, M.J. ORCID: https://orcid.org/0000-0003-3562-2099, Kasparek, P., King, R.E. ORCID: https://orcid.org/0000-0001-6733-8805, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Lee, H., Lee, Y.J. ORCID: https://orcid.org/0000-0002-3841-1994, Liu, Z., Lloyd, K.C.K. ORCID: https://orcid.org/0000-0002-5318-4144, Lorenzo, I., Mallon, A.M., McKerlie, C. ORCID: https://orcid.org/0000-0002-2232-0967, Meehan, T.F., Fuentes, V.M. ORCID: https://orcid.org/0000-0003-3574-546X, Newman, S., Nutter, L.M.J. ORCID: https://orcid.org/0000-0001-9619-146X, Oh, G.T. ORCID: https://orcid.org/0000-0002-1104-1698, Pavlovic, G. ORCID: https://orcid.org/0000-0001-9122-4592, Ramirez-Solis, R., Rosen, B., Ryder, E.J., Santos, L.A., Schick, J. ORCID: https://orcid.org/0000-0002-8623-4910, Seavitt, J.R., Sedlacek, R. ORCID: https://orcid.org/0000-0002-3352-392X, Seisenberger, C., Seong, J.K., Skarnes, W.C., Sorg, T., Steel, K.P., Tamura, M., Tocchini-Valentini, G.P., Wang, C.K.L., Wardle-Jones, H., Wattenhofer-Donzé, M. ORCID: https://orcid.org/0000-0002-6092-274X, Wells, S., Wiles, M.V., Willis, B.J., Wood, J.A., Wurst, W., Xu, Y. ORCID: https://orcid.org/0000-0002-6689-7768, Teboul, L. ORCID: https://orcid.org/0000-0002-2789-8637 and Murray, S.A. ORCID: https://orcid.org/0000-0002-0594-1702
Nature Genetics 53
(4): 416-419.
April 2021
Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient.
Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Radke, J., Eurich, D., Wiener, E., Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Anagnostopoulos, I., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Heppner, F.L., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Leukemia & Lymphoma 62
(8): 2026-2029.
August 2021
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Bloehdorn, J. ORCID: https://orcid.org/0000-0003-1433-9702, Braun, A. ORCID: https://orcid.org/0000-0003-0925-5598, Taylor-Weiner, A., Jebaraj, B.M.C., Robrecht, S., Krzykalla, J., Pan, H., Giza, A., Akylzhanova, G., Holzmann, K., Scheffold, A., Johnston, H.E., Yeh, R.F., Klymenko, T., Tausch, E., Eichhorst, B., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Fischer, K., Weisser, M., Robak, T. ORCID: https://orcid.org/0000-0002-3411-6357, Schneider, C., Gribben, J. ORCID: https://orcid.org/0000-0002-8505-7430, Dahal, L.N. ORCID: https://orcid.org/0000-0001-8390-6593, Carter, M.J., Elemento, O. ORCID: https://orcid.org/0000-0002-8061-9617, Landau, D.A. ORCID: https://orcid.org/0000-0003-2346-9541, Neuberg, D.S. ORCID: https://orcid.org/0000-0003-2566-3145, Cragg, M.S., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Hallek, M., Wu, C.J. ORCID: https://orcid.org/0000-0002-3348-5054, Döhner, H., Stilgenbauer, S. and Mertens, D.
Nature Communications 12
(1): 5395.
13 September 2021
Gene expression profiling predicts sensitivity of chronic lymphocytic leukemia cells to dasatinib.
Blätte, T.J., Machnicki, M.M., Glodkowska-Mrowka, E., Dolnik, A., Karp, M., Karczmarczyk, A., Giannopoulos, K., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Stoklosa, T.
HemaSphere 5
(1): e514.
January 2021
Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma.
Bohl, S.R., Schmalbrock, L.K. ORCID: https://orcid.org/0000-0002-6080-6175, Bauhuf, I., Meyer, T., Dolnik, A., Szyska, M. ORCID: https://orcid.org/0000-0002-4213-4600, Blätte, T.J. ORCID: https://orcid.org/0000-0002-9859-1261, Knödler, S., Röhner, L. ORCID: https://orcid.org/0000-0003-1474-8039, Miller, D., Kull, M., Langer, C., Döhner, H., Letai, A., Damm, F., Heckl, D., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Krönke, J. ORCID: https://orcid.org/0000-0002-4649-0506
Blood Advances 5
(9): 2391-2402.
11 May 2021
PET-guided omission of radiotherapy in early-stage unfavourable Hodgkin lymphoma (GHSG HD17): a multicentre, open-label, randomised, phase 3 trial.
Borchmann, P., Plütschow, A., Kobe, C., Greil, R., Meissner, J., Topp, M.S., Ostermann, H., Dierlamm, J., Mohm, J., Thiemer, J., Sökler, M., Kerkhoff, A., Ahlborn, M., Halbsguth, T.V., Martin, S., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Balabanov, S., Pabst, T., Vogelhuber, M., Hüttmann, A., Wilhelm, M., Zijlstra, J.M., Moccia, A., Kuhnert, G., Bröckelmann, P.J., von Tresckow, B., Fuchs, M., Klimm, B., Rosenwald, A., Eich, H., Baues, C., Marnitz, S., Hallek, M., Diehl, V., Dietlein, M. and Engert, A.
Lancet Oncology 22
(2): 223-234.
February 2021
Impact of a specialised palliative care intervention in patients with advanced soft tissue sarcoma - a single-centre retrospective analysis.
Brandes, F., Striefler, J.K., Dörr, A., Schmiester, M., Märdian, S., Koulaxouzidis, G., Kaul, D., Behzadi, A., Thuss-Patience, P., Ahn, J., Pelzer, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Flörcken, A.
BMC Palliative Care 20
(1): 16.
14 January 2021
M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
Breitkreuz-Korff, O., Tscheik, C., Del Vecchio, G., Dithmer, S., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Orthmann, A., Wolburg, H., Haseloff, R.F., Schröder, L., Blasig, I.E. and Winkler, L. ORCID: https://orcid.org/0000-0003-3350-1189
Journal of Controlled Release 330
: 137-148.
10 August 2021
Does the proteasome inhibitor bortezomib sensitize to DNA-damaging therapy in gastroenteropancreatic neuroendocrine neoplasms? - A preclinical assessment in vitro and in vivo.
Briest, F., Koziolek, E.J., Albrecht, J., Schmidt, F., Bernsen, M.R., Haeck, J., Kühl, A.A., Sedding, D., Hartung, T., Exner, S., Welzel, M., Fischer, C., Grötzinger, C., Brenner, W., Baum, R.P. and Grabowski, P.
Neoplasia 23
(1): 80-98.
January 2021
NF-κB determines Paneth versus goblet cell fate decision in the small intestine.
Brischetto, C. ORCID: https://orcid.org/0000-0001-9167-3291, Krieger, K., Klotz, C., Krahn, I., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Mucka, P. ORCID: https://orcid.org/0000-0003-2125-0634, Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129 and Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530
Development 148
(21): dev199683.
November 2021
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann, J. ORCID: https://orcid.org/0000-0002-1306-2169, Lorenz, C., Borchmann, S., Nishii, K., Wegner, J. ORCID: https://orcid.org/0000-0001-8103-8040, Meder, L., Ostendorp, J., Ast, D.F., Heimsoeth, A., Nakasuka, T., Hirabae, A., Okawa, S., Dammert, M.A. ORCID: https://orcid.org/0000-0003-4269-7822, Plenker, D. ORCID: https://orcid.org/0000-0003-3895-4064, Klein, S., Lohneis, P. ORCID: https://orcid.org/0000-0002-4797-0018, Gu, J., Godfrey, L.K., Forster, J., Trajkovic-Arsic, M., Zillinger, T. ORCID: https://orcid.org/0000-0002-0866-4835, Haarmann, M., Quaas, A., Lennartz, S., Schmiel, M., D'Rozario, J. ORCID: https://orcid.org/0000-0002-3380-4801, Thomas, E.S., Li, H. ORCID: https://orcid.org/0000-0002-4673-1234, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, George, J. ORCID: https://orcid.org/0000-0002-4272-3683, Thomas, R.K., von Karstedt, S. ORCID: https://orcid.org/0000-0002-7816-5919, Hartmann, G. ORCID: https://orcid.org/0000-0003-1021-2018, Büttner, R. ORCID: https://orcid.org/0000-0001-8806-4786, Ullrich, R.T., Siveke, J.T. ORCID: https://orcid.org/0000-0002-8772-4778, Ohashi, K., Schlee, M. ORCID: https://orcid.org/0000-0003-3671-7639 and Sos, M.L. ORCID: https://orcid.org/0000-0002-2868-100X
Nature Communications 12
(1): 5505.
17 September 2021
Systematic identification of A-to-I RNA editing in zebrafish development and adult organs.
Buchumenski, I., Holler, K. ORCID: https://orcid.org/0000-0002-5159-9223, Appelbaum, L. ORCID: https://orcid.org/0000-0002-9248-5919, Eisenberg, E. ORCID: https://orcid.org/0000-0001-8681-3202, Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Levanon, E.Y. ORCID: https://orcid.org/0000-0002-3641-4198
Nucleic Acids Research 49
(8): 4325-4337.
7 May 2021
Structural evidence of active site adaptability towards different sized substrates of aromatic amino acid aminotransferase from Psychrobacter sp. B6.
Bujacz, A. ORCID: https://orcid.org/0000-0002-0808-1349, Rum, J., Rutkiewicz, M. ORCID: https://orcid.org/0000-0001-8339-3230, Pietrzyk-Brzezinska, A.J. and Bujacz, G. ORCID: https://orcid.org/0000-0002-3787-7522
Materials 14
(12): 3351.
2 June 2021
CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells.
Bunse, M. ORCID: https://orcid.org/0000-0002-7554-2520, Pfeilschifter, J. ORCID: https://orcid.org/0000-0002-4534-0995, Bluhm, J., Zschummel, M. ORCID: https://orcid.org/0000-0002-4778-8742, Joedicke, J.J. ORCID: https://orcid.org/0000-0002-4708-3216, Wirges, A. ORCID: https://orcid.org/0000-0001-7038-4503, Stark, H. ORCID: https://orcid.org/0000-0002-5726-3958, Kretschmer, V., Chmielewski, M., Uckert, W., Abken, H. ORCID: https://orcid.org/0000-0002-4302-3240, Westermann, J., Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950 and Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893
Nature Communications 12
(1): 240.
11 January 2021
Non-coding RNAs: lncRNAs, miRNAs, and piRNAs in sexual development.
Burgos, M. ORCID: https://orcid.org/0000-0003-4446-9313, Hurtado, A. ORCID: https://orcid.org/0000-0001-6267-704X, Jiménez, R. ORCID: https://orcid.org/0000-0003-4103-8219 and Barrionuevo, F.J.
Sexual Development 15
(5-6): 335-350.
December 2021
Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M. ORCID: https://orcid.org/0000-0001-7132-8079, Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M. ORCID: https://orcid.org/0000-0002-9373-4753, Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Butter, C., Felix, S.B., Otto, O., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199, Slevogt, H. and Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 12
(6): 1653-1668.
December 2021
Gene therapy "Made in Germany": a historical perspective, analysis of the status quo, and recommendations for action by the German Society for Gene Therapy.
Büning, H., Fehse, B., Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658, Kochanek, S., Koehl, U., Kupatt, C., Mussolino, C., Nettelbeck, D.M., Schambach, A., Uckert, W., Wagner, E. and Cathomen, T.
Human Gene Therapy 32
(19-20): 987-996.
18 October 2021
Single cell biology - a Keystone Symposia report.
Cable, J., Elowitz, M.B., Domingos, A.I., Habib, N., Itzkovitz, S., Hamidzada, H., Balzer, M.S., Yanai, I., Liberali, P., Whited, J., Streets, A., Cai, L., Stergachis, A.B., Hong, C.K.Y., Keren, L., Guilliams, M., Alon, U., Shalek, A.K., Hamel, R., Pfau, S.J., Raj, A., Quake, S.R., Zhang, N.R., Fan, J., Trapnell, C., Wang, B., Greenwald, N.F., Vento-Tormo, R., Santos, S.D.M., Spencer, S.L., Garcia, H.G., Arekatla, G., Gaiti, F., Arbel-Goren, R., Rulands, S., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290, Klein, A.M., Morris, S.A., Murray, J.I., Galloway, K.E., Ratz, M. and Romeike, M.
Annals of the New York Academy of Sciences 1506
(1): 74-97.
December 2021
Cancer stem cells: advances in biology and clinical translation -- a Keystone Symposia report.
Cable, J., Pei, D., Reid, L.M., Wang, X.W., Bhatia, S., Karras, P., Melenhorst, J.J., Grompe, M., Lathia, J.D., Song, E., Kuo, C.J., Zhang, N., White, R.M., Ma, S.K., Ma, L., Chin, Y.R., Shen, M.M., Ng, I.O.L., Kaestner, K.H., Zhou, L., Sikandar, S., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Guo, W., Wong, C.C.L., Ji, J., Tang, D.G., Dubrovska, A., Yang, C., Wiedemeyer, W.R. and Weissman, I.L.
Annals of the New York Academy of Sciences 1506
(1): 142–163.
December 2021
DDX3 depletion represses translation of mRNAs with complex 5' UTRs.
Calviello, L. ORCID: https://orcid.org/0000-0002-5600-0988, Venkataramanan, S. ORCID: https://orcid.org/0000-0002-2507-401X, Rogowski, K.J. ORCID: https://orcid.org/0000-0003-4560-0715, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Wilkins, K., Tejura, M., Thai, B., Krol, J., Filipowicz, W., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Floor, S.N. ORCID: https://orcid.org/0000-0002-9965-9694
Nucleic Acids Research 49
(9): 5336-5350.
May 2021
Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.
Carley, L.N. ORCID: https://orcid.org/0000-0003-1911-7025, Mojica, J.P., Wang, B., Chen, C.Y. ORCID: https://orcid.org/0000-0003-1765-7132, Lin, Y.P. ORCID: https://orcid.org/0000-0002-9575-2007, Prasad, K.V.S.K ORCID: https://orcid.org/0000-0002-9518-2104, Chan, E., Hsu, C.W. ORCID: https://orcid.org/0000-0003-3709-9748, Keith, R., Nuñez, C.L. ORCID: https://orcid.org/0000-0002-3273-6966, Olson-Manning, C.F. ORCID: https://orcid.org/0000-0001-8054-3889, Rushworth, C.A. ORCID: https://orcid.org/0000-0003-0715-1234, Wagner, M.R. ORCID: https://orcid.org/0000-0002-6924-7226, Wang, J., Yeh, P.M. ORCID: https://orcid.org/0000-0002-3902-6115, Reichelt, M. ORCID: https://orcid.org/0000-0002-6691-6500, Ghattas, K., Gershenzon, J. ORCID: https://orcid.org/0000-0002-1812-1551, Lee, C.R. ORCID: https://orcid.org/0000-0002-1913-9964 and Mitchell-Olds, T. ORCID: https://orcid.org/0000-0003-3439-9921
Nature Ecology & Evolution 5
: 1135-1144.
August 2021
Enhanced properties of a benzimidazole benzylpyrazole lysine demethylase inhibitor: mechanism-of-action, binding site analysis, and activity in cellular models of prostate cancer.
Carter, D.M. ORCID: https://orcid.org/0000-0002-2517-8599, Specker, E. ORCID: https://orcid.org/0000-0002-9471-9520, Malecki, P.H. ORCID: https://orcid.org/0000-0003-1499-8310, Przygodda, J., Dudaniec, K., Weiss, M.S., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330 and Gohlke, U.
Journal of Medicinal Chemistry 64
(19): 14266-14282.
14 October 2021
Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G. ORCID: https://orcid.org/0000-0001-9772-1012, Bay, O., Zinno, J., Gutwein, M., Gan, H.H., Mayya, V.K., Chung, G., Chen, J.X. ORCID: https://orcid.org/0000-0002-3671-553X, Fahs, H., Guan, Y., Duchaine, T.F., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Piano, F. and Gunsalus, K.C. ORCID: https://orcid.org/0000-0001-9769-4624
eLife 10
: e60833.
3 August 2021
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Gambara, G. ORCID: https://orcid.org/0000-0001-8921-2568, Brzezicha, B., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Pachmayr, E., Wedeken, L. ORCID: https://orcid.org/0000-0003-1061-9459, Pflaume, A., Mokritzkij, M., Gül-Klein, S. ORCID: https://orcid.org/0000-0003-1013-7126, Brandl, A. ORCID: https://orcid.org/0000-0003-1990-2584, Schweiger-Eisbacher, C., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Hoffmann, J. ORCID: https://orcid.org/0000-0003-3880-1658, Keilholz, U. ORCID: https://orcid.org/0000-0001-6773-9406, Walther, W. ORCID: https://orcid.org/0000-0003-2360-1370, Regenbrecht, C. ORCID: https://orcid.org/0000-0001-9494-5977, Rau, B. ORCID: https://orcid.org/0000-0001-5820-6907 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Molecular Cancer 20
(1): 129.
21 October 2021
A bioinformatic pipeline to identify biomarkers for metastasis formation from RNA sequencing data.
Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283 and Stein, U.S. ORCID: https://orcid.org/0000-0001-7006-282X
Methods in Molecular Biology 2294
: 221-238.
2021
Early bilirubinemia after allogeneic stem cell transplantation - an endothelial complication.
Dai, H., Penack, O., Radujkovic, A., Schult, D., Majer-Lauterbach, J., Blau, I.W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Jiang, S., Müller-Tidow, C., Dreger, P. ORCID: https://orcid.org/0000-0002-7429-8570 and Luft, T.
Bone Marrow Transplantation 56
(7): 1573-1583.
July 2021
A homology independent sequence replacement strategy in human cells using a CRISPR nuclease.
Danner, E. ORCID: https://orcid.org/0000-0003-3277-5727, Lebedin, M. ORCID: https://orcid.org/0000-0002-3877-7195, de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157 and Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803
Open Biology 11
(1): 200283.
January 2021
Thyrotropin receptor-specific lymphocytes in adenovirus-TSHR-immunized native and human leukocyte antigen-DR3-transgenic mice and in Graves' disease patient blood.
Degen, H., Gavvovidis, I. ORCID: https://orcid.org/0000-0001-5644-9788, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Uhland, K. and Ungerer, M.
Thyroid 31
(6): 950-963.
June 2021
Elevated Flt3L predicts long-term survival in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms.
Detjen, K.M., Otto, R. ORCID: https://orcid.org/0000-0003-3644-743X, Giesecke, Y., Geisler, L., Riemer, P., Jann, H., Grötzinger, C. ORCID: https://orcid.org/0000-0001-9872-3087, Sers, C., Pascher, A., Lüdde, T., Leser, U., Wiedenmann, B., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761, Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226, Roderburg, C. and Hammerich, L. ORCID: https://orcid.org/0000-0003-0557-3927
Cancers 13
(17): 4463.
1 September 2021
„Liquid biopsies“ als neue Diagnostikplattform in der pädiatrischen Onkologie [Liquid biopsies as a new diagnostic platform in pediatric oncology].
Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Eggert, A. and Pajtler, K. W.
Onkologe 27
(5): 458-463.
May 2021
Personalisierte Medizin in der Kinderonkologie: Wo stehen wir heute?
Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201 and Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184
Pädiatrie up2date 16
(4): 325-342.
December 2021
Structure of the merozoite surface protein 1 from Plasmodium falciparum.
Dijkman, P.M., Marzluf, T., Zhang, Y., Chang, S.Y.S. ORCID: https://orcid.org/0000-0002-5627-9106, Helm, D., Lanzer, M., Bujard, H. and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
Science Advances 7
(23): eabg0465.
June 2021
COVID19-associated cardiomyocyte dysfunction, arrhythmias and the effect of Canakinumab.
Dimai, S., Semmler, L., Prabhu, A., Stachelscheid, H. ORCID: https://orcid.org/0000-0002-9283-4605, Huettemeister, J., Klaucke, S.C., Lacour, P., Blaschke, F. ORCID: https://orcid.org/0000-0001-7193-0318, Kruse, J., Parwani, A., Boldt, L.H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Pieske, B.M. ORCID: https://orcid.org/0000-0002-6466-5306, Heinzel, F.R. and Hohendanner, F. ORCID: https://orcid.org/0000-0002-0194-4615
PLoS ONE 16
(8): e0255976.
19 August 2021
Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Divangahi, M. ORCID: https://orcid.org/0000-0002-1254-6110, Aaby, P.r, Khader, S.A. ORCID: https://orcid.org/0000-0002-9545-4982, Barreiro, L.B., Bekkering, S. ORCID: https://orcid.org/0000-0003-1149-466X, Chavakis, T. ORCID: https://orcid.org/0000-0002-1869-5141, van Crevel, R., Curtis, N., DiNardo, A.R., Dominguez-Andres, J. ORCID: https://orcid.org/0000-0002-9091-1961, Duivenvoorden, R., Fanucchi, S., Fayad, Z. ORCID: https://orcid.org/0000-0002-3439-7347, Fuchs, E., Hamon, M. ORCID: https://orcid.org/0000-0001-5078-4083, Jeffrey, K.L. ORCID: https://orcid.org/0000-0001-5746-0153, Khan, N., Joosten, L.A.B. ORCID: https://orcid.org/0000-0001-6166-9830, Kaufmann, E., Latz, E. ORCID: https://orcid.org/0000-0003-1488-5666, Matarese, G. ORCID: https://orcid.org/0000-0001-9429-0616, van der Meer, J.W.M., Mhlanga, M. ORCID: https://orcid.org/0000-0003-1381-3409, Moorlag, S.J.C.F.M., Mulder, W.J.M. ORCID: https://orcid.org/0000-0001-8665-3878, Naik, S., Novakovic, B., O'Neill, L. ORCID: https://orcid.org/0000-0002-4333-2748, Ochando, J. ORCID: https://orcid.org/0000-0001-7037-1681, Ozato, K., Riksen, N.P. ORCID: https://orcid.org/0000-0001-9197-8124, Sauerwein, R., Sherwood, E.R., Schlitzer, A., Schultze, J.L., Sieweke, M.H. ORCID: https://orcid.org/0000-0002-3228-9537, Benn, C.S., Stunnenberg, H., Sun, J. ORCID: https://orcid.org/0000-0001-8062-9033, van de Veerdonk, F.L. ORCID: https://orcid.org/0000-0002-1121-4894, Weis, S. ORCID: https://orcid.org/0000-0003-3201-2375, Williams, D.L., Xavier, R. ORCID: https://orcid.org/0000-0002-5630-5167 and Netea, M.G. ORCID: https://orcid.org/0000-0003-2421-6052
Nature Immunology 22
(1): 2-6.
January 2021
Genome sequencing in myeloid cancers.
Dolnik, A., Schrezenmeier, J. ORCID: https://orcid.org/0000-0001-5239-4513 and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
New England Journal of Medicine 384
(25): e106.
24 June 2021
Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M. ORCID: https://orcid.org/0000-0002-1663-2075, Klinger, B. ORCID: https://orcid.org/0000-0003-0242-1506, Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Messerschmidt, C. ORCID: https://orcid.org/0000-0001-8632-656X, Nadler-Holly, M., Ziehm, M. ORCID: https://orcid.org/0000-0001-7074-4054, Sieber, A. ORCID: https://orcid.org/0000-0001-6588-8547, Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Eggert, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447
PLoS Computational Biology 17
(11): e1009515.
4 November 2021
Modeling Structure-Activity Relationship of AMPK Activation.
Drewe, J. ORCID: https://orcid.org/0000-0001-5178-7825, Küsters, E., Hammann, F. ORCID: https://orcid.org/0000-0003-0658-9330, Kreuter, M., Boss, P. ORCID: https://orcid.org/0000-0002-5459-9771 and Schöning, V. ORCID: https://orcid.org/0000-0003-2105-326X
Molecules 26
(21): 6508.
1 November 2021
Generation of Epstein-Barr virus antigen-specific T cell receptors recognizing immunodominant epitopes of LMP1, LMP2A, and EBNA3C for immunotherapy.
Dudaniec, K., Westendorf, K., Nössner, E. and Uckert, W.
Human Gene Therapy 32
(17-18): 919-935.
21 September 2021
Evaluation of aggression and fearfulness in domestic dog (Canis familiaris).
Dyjak, M., Boruta, A., Adamkiewicz, E., Walasek, A., Bury-Burzymski, P. and Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072
Animal Science Papers and Reports 39
(4): 407-418.
2021
The EHA Research Roadmap: Malignant Myeloid Diseases.
Döhner, H., Malcovati, L., Ossenkoppele, G.J., Hochhaus, A., Maria Vannucchi, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Cervantes, F., Craddock, C., de Witte, T., Döhner, K., Dombret, H., Fenaux, P., Geissler, J., Germing, U., Guilhot, F., Harrison, C., Hellström-Lindberg, E., Passamonti, F., Sierra, J., Skoda, R. and Wierzbowska, A.
HemaSphere 5
(9): e635.
September 2021
Germline mutations including the rare pathogenic variant c.3206delC in the ATM gene cause ataxia teleangiectasia-associated primary central nervous system lymphoma.
Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Thorwarth, A., Mizia-Malarz, A. ORCID: https://orcid.org/0000-0002-1984-5527, Radke, J. ORCID: https://orcid.org/0000-0001-9860-2007, Tietze, A., Hernáiz-Driever, P. ORCID: https://orcid.org/0000-0003-3135-3872, Horn, D., Gratopp, A., Eggert, A. and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Children 8
(6): 469.
June 2021
Haplotype-resolved diverse human genomes and integrated analysis of structural variation.
Ebert, P., Audano, P. A., Zhu, Q., Rodriguez-Martin, B., Porubsky, D., Bonder, M.J., Sulovari, A., Ebler, J., Zhou, W., Serra Mari, R., Yilmaz, F., Zhao, X., Hsieh, P.H., Lee, J., Kumar, S., Lin, J., Rausch, T., Chen, Y., Ren, J., Santamarina, M., Höps, W., Ashraf, H., Chuang, N.T., Yang, X., Munson, K.M., Lewis, A.P., Fairley, S., Tallon, L.J., Clarke, W.E., Basile, A.O., Byrska-Bishop, M., Corvelo, A., Evani, U.S., Lu, T.Y., Chaisson, M.J.P., Chen, J., Li, C., Brand, H., Wenger, A.M., Ghareghani, M., Harvey, W.T., Raeder, B., Hasenfeld, P., Regier, A.A., Abel, H.J., Hall, I.M., Flicek, P., Stegle, O., Gerstein, M.B, Tubio, J.M.C., Mu, Z., Li, Y.I., Shi, X., Hastie, A.R., Ye, K., Chong, Z., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Zody, M.C., Talkowski, M.E., Mills, R. E., Devine, S.E., Lee, C., Korbel, J.O., Marschall, T. and Eichler, E.E.
Science 372
(6537): eabf7117.
25 February 2021
ASHLEYS: automated quality control for single-cell Strand-seq data.
Eimer, C. ORCID: https://orcid.org/0000-0001-6124-2669, Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Korbel, J.O., Marschall, T. ORCID: https://orcid.org/0000-0002-9376-1030 and Ebert, P. ORCID: https://orcid.org/0000-0001-7441-532X
Bioinformatics 37
(19): 3356-3357.
1 October 2021
Thymoquinone: a tie-breaker in SARS-CoV2-infected cancer patients?
Elgohary, S. ORCID: https://orcid.org/0000-0002-1655-2665, Elkhodiry, A.A. ORCID: https://orcid.org/0000-0001-5684-0242, Amin, N.S. ORCID: https://orcid.org/0000-0002-9541-549X, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and El Tayebi, H.M. ORCID: https://orcid.org/0000-0002-6896-6018
Cells 10
(2): 302.
2 February 2021
Base editing repairs an SGCA mutation in human primary muscle stem cells.
Escobar, H. ORCID: https://orcid.org/0000-0002-8128-7845, Krause, A. ORCID: https://orcid.org/0000-0001-9515-2477, Keiper, S., Kieshauer, J. ORCID: https://orcid.org/0000-0002-6924-8616, Müthel, S. ORCID: https://orcid.org/0000-0002-3525-8859, García de Paredes, M., Metzler, E. ORCID: https://orcid.org/0000-0003-1735-6364, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Heyd, F. and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
JCI Insight 6
(10): e145994.
24 May 2021
An autochthonous mouse model of Myd88- and BCL2-driven diffuse large B-cell lymphoma reveals actionable molecular vulnerabilities.
Flümann, R., Rehkämper, T., Nieper, P., Pfeiffer, P., Holzem, A., Klein, S., Bhatia, S., Kochanek, M., Kisis, I., Pelzer, B.W., Ahlert, H., Hauer, J., da Palma Guerreiro, A., Ryan, J.A., Reimann, M., Riabinska, A., Wiederstein, J., Krüger, M., Deckert, M., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Klatt, A.R., Frenzel, L.P., Pasqualucci, L., Béguelin, W., Melnick, A.M., Sander, S., Montesinos-Rongen, M., Brunn, A., Lohneis, P., Büttner, R., Kashkar, H., Borkhardt, A., Letai, A., Persigehl, T., Peifer, M., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Reinhardt, H.C. and Knittel, G.
Blood Cancer Discovery 2
(1): 70-91.
January 2021
Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics.
Franz, A., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Shen, C., Charaoui, L., Mann, M. and Sander, C. ORCID: https://orcid.org/0000-0001-6059-6270
Journal of Ovarian Research 14
(1): 140.
22 October 2021
RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells.
Fu, R., Wellman, K., Baldwin, A., Rege, J., Walters, K., Hirsekorn, A., Riemondy, K., Rainey, W.E and Mukherjee, N.
RNA 27
(8): 933-945.
August 2021
A multimodal platform for simultaneous T-cell imaging, defined activation, and mechanobiological characterization.
Fölser, M., Motsch, V. ORCID: https://orcid.org/0000-0002-4860-4247, Platzer, R., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089
Cells 10
(2): 235.
February 2021
Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects.
Galgoczi, S. ORCID: https://orcid.org/0000-0001-8248-3314, Ruzo, A., Markopoulos, C., Yoney, A. ORCID: https://orcid.org/0000-0003-4988-9237, Phan-Everson, T., Li, S., Haremaki, T., Metzger, J.J. ORCID: https://orcid.org/0000-0001-6813-4425, Etoc, F. and Brivanlou, A.H. ORCID: https://orcid.org/0000-0002-1761-280X
Development 148
(19): dev199513.
October 2021
Landscape of HER2-low metastatic breast cancer (MBC): results from the Austrian AGMT_MBC-Registry.
Gampenrieder, S.P., Rinnerthaler, G., Tinchon, C., Petzer, A., Balic, M., Heibl, S., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Zabernigg, A.F., Egle, D., Sandholzer, M., Singer, C.F., Roitner, F., Hager, C., Andel, J., Hubalek, M., Knauer, M. and Greil, R. ORCID: https://orcid.org/0000-0002-4462-3694
Breast Cancer Research 23
(1): 112.
14 December 2021
Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor.
Ganichkin, O.M., Vancraenenbroeck, R. ORCID: https://orcid.org/0000-0003-2685-2749, Rosenblum, G., Hofmann, H. ORCID: https://orcid.org/0000-0003-1669-3158, Mikhailov, A.S. ORCID: https://orcid.org/0000-0002-2416-8401, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036
Proceedings of the National Academy of Sciences of the United States of America 118
(28): e2101144118.
13 July 2021
PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Garg, A. ORCID: https://orcid.org/0000-0003-2397-1670, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Yamada, S., Uehata, T., Takeuchi, O. ORCID: https://orcid.org/0000-0002-1260-6232 and Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850
Nucleic Acids Research 49
(9): 5369-5381.
21 May 2021
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Gassen, N.C. ORCID: https://orcid.org/0000-0002-4265-3398, Papies, J., Bajaj, T., Emanuel, J. ORCID: https://orcid.org/0000-0002-6246-5255, Dethloff, F., Chua, R.L. ORCID: https://orcid.org/0000-0001-5945-9957, Trimpert, J. ORCID: https://orcid.org/0000-0003-1616-0810, Heinemann, N., Niemeyer, C., Weege, F. ORCID: https://orcid.org/0000-0003-2428-1065, Hönzke, K., Aschman, T. ORCID: https://orcid.org/0000-0002-2101-6146, Heinz, D.E. ORCID: https://orcid.org/0000-0001-7103-9621, Weckmann, K., Ebert, T., Zellner, A., Lennarz, M., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Schroeder, S., Richter, A., Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Hoffmann, K., Meyer, T.F., Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917, Corman, V.M. ORCID: https://orcid.org/0000-0002-3605-0136, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Hocke, A.C., Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Osterrieder, N., Conrad, C., Eils, R. ORCID: https://orcid.org/0000-0002-0034-4036, Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Giavalisco, P., Drosten, C. ORCID: https://orcid.org/0000-0001-7923-0519 and Müller, M.A. ORCID: https://orcid.org/0000-0003-2242-5117
Nature Communications 12
(1): 3818.
21 June 2021
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.
Giacopelli, B., Wang, M., Cleary, A., Wu, Y.Z., Schultz, A.R., Schmutz, M., Blachly, J.S., Eisfeld, A.K., Mundy-Bosse, B., Vosberg, S., Greif, P.A., Claus, R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Garzon, R., Coombes, K.R., Bloomfield, C.D., Druker, B.J., Tyner, J.W., Byrd, J.C. and Oakes, C.C.
Genome Research 31
(5): 747-761.
May 2021
Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin.
Gillissen, B., Richter, A., Essmann, F. and Kemmner, W. ORCID: https://orcid.org/0000-0002-1494-7225
BMC Cancer 21
(1): 971.
30 August 2021
Editorial: Monocyte heterogeneity and function.
Ginhoux, F., Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427, Gautier, E.L., Schlitzer, A., Jakubzick, C., Varol, C., Bain, C. and Guermonprez, P.
Frontiers in Immunology 11
: 626725.
7 January 2021
The zinc finger antiviral protein ZAP restricts human cytomegalovirus and selectively binds and destabilizes viral UL4/UL5 transcripts.
Gonzalez-Perez, A.C. ORCID: https://orcid.org/0000-0002-8674-1525, Stempel, M. ORCID: https://orcid.org/0000-0002-9240-3987, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Urban, C., Piras, A., Hennig, T. ORCID: https://orcid.org/0000-0002-7788-1681, Ganskih, S., Wei, Y., Heim, A. ORCID: https://orcid.org/0000-0002-9447-1561, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Pichlmair, A., Dölken, L., Munschauer, M. ORCID: https://orcid.org/0000-0001-6143-4548, Erhard, F. and Brinkmann, M.M. ORCID: https://orcid.org/0000-0001-5431-6527
mBio 12
(3): e02683-20.
4 May 2021
MLL1 is required for maintenance of intestinal stem cells.
Goveas, N. ORCID: https://orcid.org/0000-0002-2531-5514, Waskow, C. ORCID: https://orcid.org/0000-0003-3261-0922, Arndt, K., Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Zhang, Q. ORCID: https://orcid.org/0000-0001-8292-938X, Alexopoulou, D. ORCID: https://orcid.org/0000-0002-3715-1756, Dahl, A., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Anastassiadis, K. ORCID: https://orcid.org/0000-0002-9814-0559, Stewart, A.F. ORCID: https://orcid.org/0000-0002-4754-1707 and Kranz, A. ORCID: https://orcid.org/0000-0002-7481-0220
PLoS Genetics 17
(12): e1009250.
3 December 2021
Survivin’ acute myeloid leukaemia - a personalised target for inv(16) patients.
Greiner, J. ORCID: https://orcid.org/0000-0003-1256-173X, Brown, E., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Hills, R.K., Morris, V., Döhner, H., Mills, K.I. ORCID: https://orcid.org/0000-0002-6362-4481 and Guinn, B.A. ORCID: https://orcid.org/0000-0003-0639-4541
International Journal of Molecular Sciences 22
(19): 10482.
1 October 2021
A reproducible bioprinted 3D tumor model serves as a preselection tool for CAR T cell therapy optimization.
Grunewald, L., Lam, T., Andersch, L., Klaus, A., Schwiebert, S., Winkler, A., Gauert, A. ORCID: https://orcid.org/0000-0002-3013-5374, Heeren-Hagemann, A.I., Astrahantseff, K., Klironomos, F., Thomas, A., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Anders, K. ORCID: https://orcid.org/0000-0002-0429-200X, Kloke, L. and Künkele, A.
Frontiers in Immunology 12
: 689697.
29 June 2021
How to find genomic regions relevant for gene regulation.
Guo, X., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Yildirim, F.
Medizinische Genetik 33
(2): 157-165.
14 August 2021
Temporal analysis of T-cell receptor-imposed forces via quantitative single molecule FRET measurements.
Göhring, J. ORCID: https://orcid.org/0000-0002-6755-5305, Kellner, F. ORCID: https://orcid.org/0000-0001-5931-3798, Schrangl, L. ORCID: https://orcid.org/0000-0002-0420-7872, Platzer, R., Klotzsch, E., Stockinger, H. ORCID: https://orcid.org/0000-0001-6404-4430, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089
Nature Communications 12
(1): 2502.
4 May 2021
A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3.
Halatsch, M.E., Kast, R.E., Karpel-Massler, G., Mayer, B., Zolk, O., Schmitz, B., Scheuerle, A., Maier, L., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mayer-Steinacker, R., Schmidt, C., Zeiler, K., Elshaer, Z., Panther, P., Schmelzle, B., Hallmen, A., Dwucet, A., Siegelin, M.D., Westhoff, M.A., Beckers, K., Bouche, G. and Heiland, T.
Neuro-Oncology Advances 3
(1): vdab075.
7 August 2021
Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice.
Hammer, K.P. ORCID: https://orcid.org/0000-0003-2015-0682, Mustroph, J. ORCID: https://orcid.org/0000-0001-9668-7852, Stauber, T., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Wagner, S. and Maier, L.S.
PLoS ONE 16
(6): e0252649.
4 June 2021
Histone deacetylase 1 controls CD4(+) T cell trafficking in autoinflammatory diseases.
Hamminger, P., Marchetti, L., Preglej, T., Platzer, R., Zhu, C., Kamnev, A., Rica, R., Stolz, V., Sandner, L., Alteneder, M., Kaba, E., Waltenberger, D., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Trauner, M., Bock, C., Lyck, R., Bauer, J., Dupré, L., Seiser, C., Boucheron, N., Engelhardt, B. and Ellmeier, W.
Journal of Autoimmunity 119
: 102610.
May 2021
Genome-wide analysis of actively translated open reading frames using riboTaper/ORFquant.
Harnett, D. ORCID: https://orcid.org/0000-0002-9190-128X, Meerdink, E., Calviello, L. ORCID: https://orcid.org/0000-0002-5600-0988, Sydow, D. ORCID: https://orcid.org/0000-0003-4205-8705 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Methods in Molecular Biology 2252
: 331-346.
2021
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A. ORCID: https://orcid.org/0000-0003-3746-7010, Sieverling, L. ORCID: https://orcid.org/0000-0002-0595-4976, Nadler-Holly, M., Ziehm, M. ORCID: https://orcid.org/0000-0001-7074-4054, Toprak, U.H., Herrmann, C. ORCID: https://orcid.org/0000-0003-4989-4722, Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X, Okonechnikov, K., Gartlgruber, M., Park, Y.G., Wecht, E.M., Savelyeva, L., Henrich, K.O., Rosswog, C., Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242, Hero, B., Jones, D.T.W., Pfaff, E., Witt, O., Pfister, S.M., Volckmann, Ri., Koster, J. ORCID: https://orcid.org/0000-0002-0890-7585, Kiesel, K., Rippe, K. ORCID: https://orcid.org/0000-0001-9951-9395, Taschner-Mandl, S. ORCID: https://orcid.org/0000-0002-1439-5301, Ambros, P., Brors, B. ORCID: https://orcid.org/0000-0001-5940-3101, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Feuerbach, L. ORCID: https://orcid.org/0000-0003-1503-437X and Westermann, F.
Nature Communications 12
(1): 1269.
24 February 2021
Insulin-like growth factor binding protein-2 (IGFBP2) is a key molecule in the MACC1-mediated platelet communication and metastasis of colorectal cancer cells.
Haschemi, R., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Steinwarz, E., Schlesinger, M., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Bendas, G. ORCID: https://orcid.org/0000-0002-8667-7201
International Journal of Molecular Sciences 22
(22): 12195.
11 November 2021
CD4+ T cell dependent B cell recovery and function after autologous hematopoietic stem cell transplantation.
Heck, C., Steiner, S., Kaebisch, E.M., Frentsch, M., Wittenbecher, F., Scheibenbogen, C., Hanitsch, L.G., Nogai, A., le Coutre, P., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Blau, I.W. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 12
: 736137.
September 2021
The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Heider, M., Eichner, R., Stroh, J., Morath, V., Kuisl, A., Zecha, J., Lawatscheck, J., Baek, K., Garz, A.K., Rudelius, M., Deuschle, F.C., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Lemeer, S., Verbeek, M., Götze, K.S., Skerra, A., Weber, W.A., Buchner, J., Schulman, B.A., Kuster, B., Fernández-Sáiz, V. and Bassermann, F.
Molecular Cell 81
(6): 1170-1186.
18 March 2021
Cold-shock domains - abundance, structure, properties, and nucleic-acid binding.
Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X
Cancers 13
(2): 190.
7 January 2021
DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens.
Hellmeier, J. ORCID: https://orcid.org/0000-0002-7153-9121, Platzer, R., Eklund, A.S. ORCID: https://orcid.org/0000-0003-1047-2100, Schlichthaerle, T. ORCID: https://orcid.org/0000-0003-4444-2575, Karner, A., Motsch, V. ORCID: https://orcid.org/0000-0002-4860-4247, Schneider, M.C. ORCID: https://orcid.org/0000-0002-3771-8353, Kurz, E., Bamieh, V., Brameshuber, M. ORCID: https://orcid.org/0000-0001-8672-2255, Preiner, J. ORCID: https://orcid.org/0000-0002-6755-6543, Jungmann, R. ORCID: https://orcid.org/0000-0003-4607-3312, Stockinger, H. ORCID: https://orcid.org/0000-0001-6404-4430, Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Sevcsik, E. ORCID: https://orcid.org/0000-0002-2155-1675
Proceedings of the National Academy of Sciences of the United States of America 118
(4): e2016857118.
26 January 2021
Strategies for the site-specific decoration of DNA origami nanostructures with functionally intact proteins.
Hellmeier, J., Platzer, R., Mühlgrabner, V., Schneider, M.C., Kurz, E., Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Sevcsik, E. ORCID: https://orcid.org/0000-0002-2155-1675
ACS Nano 15
(9): 15057-15068.
28 September 2021
A comparison of nine machine learning mutagenicity models and their application for predicting pyrrolizidine alkaloids.
Helma, C., Schöning, V., Drewe, J. and Boss, P. ORCID: https://orcid.org/0000-0002-5459-9771
Frontiers in Pharmacology 12
: 708050.
22 July 2021
Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.
Herda, S., Heimann, A., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Ciraolo, E. ORCID: https://orcid.org/0000-0002-5601-1695, Althoff, S., Ruß, J., Grunert, C. ORCID: https://orcid.org/0000-0001-8376-8629, Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
International Journal of Cancer 148
(12): 3097-3110.
15 June 2021
High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Grinat, J. ORCID: https://orcid.org/0000-0003-0152-4941, Kosel, F., Liu, L., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Vidal, R.O. ORCID: https://orcid.org/0000-0003-4217-2014, Keil, M. ORCID: https://orcid.org/0000-0002-6009-9845, Haybaeck, J. ORCID: https://orcid.org/0000-0001-5518-3359, Robine, S. ORCID: https://orcid.org/0000-0002-8885-0389, Louvard, D. ORCID: https://orcid.org/0000-0001-5956-7755, Regenbrecht, C. ORCID: https://orcid.org/0000-0001-9494-5977, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, von Eyss, B. ORCID: https://orcid.org/0000-0002-4731-6841, Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 118
(22): e2019699118.
1 June 2021
Epithelial response to IFN-γ promotes SARS-CoV-2 infection.
Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Trimpert, J., Vladimirova, D., Goosmann, C., Lin, M. ORCID: https://orcid.org/0000-0003-4093-9277, Schmuck, R., Mollenkopf, H.J., Brinkmann, V., Tacke, F., Osterrieder, N. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
EMBO Molecular Medicine 13
(4): e13191.
9 April 2021
Posttransplantation MRD monitoring in patients with AML by next-generation sequencing using DTA and non-DTA mutations.
Heuser, M. ORCID: https://orcid.org/0000-0001-5318-9044, Heida, B., Büttner, K., Wienecke, C.P., Teich, K., Funke, C., Brandes, M., Klement, P., Liebich, A., Wichmann, M., Neziri, B., Chaturvedi, A., Kloos, A., Mintzas, K., Gaidzik, V.I., Paschka, P., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Fiedler, W., Heim, A., Puppe, W., Krauter, J., Döhner, K., Döhner, H., Ganser, A. ORCID: https://orcid.org/0000-0003-3510-4304, Stadler, M., Hambach, L., Gabdoulline, R. and Thol, F.
Blood Advances 5
(9): 2294-2304.
11 May 2021
Construction of whole genomes from scaffolds using single cell strand-seq data.
Hills, M., Falconer, E., O'Neill, K., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Howe, K. ORCID: https://orcid.org/0000-0003-2237-513X, Guryev, V. ORCID: https://orcid.org/0000-0002-5810-6022 and Lansdorp, P.M.
International Journal of Molecular Sciences 22
(7): 3617.
1 April 2021
A public health antibody screening indicates a 6-fold higher SARS-CoV-2 exposure rate than reported cases in children.
Hippich, M., Holthaus, L., Assfalg, R., Zapardiel Gonzalo, J.M., Kapfelsperger, H., Heigermoser, M., Haupt, F., Ewald, D.A., Welzhofer, T.C., Marcus, B.A., Heck, S., Koelln, A., Stock, J., Voss, F., Secchi, M., Piemonti, L., de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157, Protzer, U., Boehmer, M., Achenbach, P., Lampasona, V., Bonifacio, E. and Ziegler, A.G.
Med 2
(2): 149-163.
12 February 2021
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.
Ho, J.S., Di Tullio, F., Schwarz, M., Low, D., Incarnato, D., Gay, F., Tabaglio, T., Zhang, J.X., Wollmann, H., Chen, L., An, O., Chan, T.H.M., Hall Hickman, A., Zheng, S., Roudko, V., Chen, S., Karz, A., Ahmed, M., He, H.H., Greenbaum, B.D., Oliviero, S. ORCID: https://orcid.org/0000-0002-3405-765X, Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658, Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251, Mann, K.M., Hernando, E., Mulholland, D., Marazzi, I., Wee, D.K.B. and Guccione, E. ORCID: https://orcid.org/0000-0001-7764-5307
eLife 10
: e59654.
2 June 2021
Spatio-temporal mRNA tracking in the early zebrafish embryo.
Holler, K. ORCID: https://orcid.org/0000-0002-5159-9223, Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Drewe-Boß, P. ORCID: https://orcid.org/0000-0002-5459-9771, Mintcheva, J. ORCID: https://orcid.org/0000-0003-0793-6277, Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Arsiè, R. ORCID: https://orcid.org/0000-0002-7869-7624, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Nature Communications 12
: 3358.
7 June 2021
A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: results from the CONKO-005 trial.
Hoyer, K., Hablesreiter, R., Inoue, Y., Yoshida, K., Briest, F., Christen, F., Kakiuchi, N., Yoshizato, T., Shiozawa, Y., Shiraishi, Y., Striefler, J.K., Bischoff, S., Lohneis, P., Putter, H., Blau, O., Keilholz, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Pelzer, U., Hummel, M., Riess, H., Ogawa, S., Sinn, M. and Damm, F.
EBioMedicine 66
: 103327.
April 2021
Mit Einzelzell-Genomik die Entscheidungen von Zellen verfolgen [Deciphering cell fate decisions using single cell genomics].
Hu, B. ORCID: https://orcid.org/0000-0003-0751-885X and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
BIOspektrum 27
(1): 25-27.
February 2021
ecDNA hubs drive cooperative intermolecular oncogene expression.
Hung, K.L., Yost, K.E., Xie, L., Shi, Q., Helmsauer, K., Luebeck, J., Schöpflin, R., Lange, J.T., Chamorro González, R., Weiser, N.E., Chen, C., Valieva, M.E., Wong, I.T.L., Wu, S., Dehkordi, S.R., Duffy, C.V., Kraft, K., Tang, J., Belk, J.A., Rose, J.C., Corces, M.R., Granja, J.M., Li, R. ORCID: https://orcid.org/0000-0002-3085-5267, Rajkumar, U., Friedlein, J., Bagchi, A., Satpathy, A.T., Tjian, R., Mundlos, S., Bafna, V., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Mischel, P.S., Liu, Z. and Chang, H.Y.
Nature 600
(7890): 731-736.
23 December 2021
Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.
Iftekhar, A. ORCID: https://orcid.org/0000-0002-0001-5590, Berger, H. ORCID: https://orcid.org/0000-0002-6304-4946, Bouznad, N., Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Boccellato, F. ORCID: https://orcid.org/0000-0001-6013-7154, Dobrindt, U., Hermeking, H., Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761 and Meyer, T.F. ORCID: https://orcid.org/0000-0002-6120-8679
Nature Communications 12
(1): 1003.
12 February 2021
Defence and adaptation mechanisms of the intestinal epithelium upon infection.
Iftekhar, A. ORCID: https://orcid.org/0000-0002-0001-5590 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
International Journal of Medical Microbiology 311
(3): 151486.
April 2021
Clinical outcome of older adults with acute myeloid leukemia: an analysis of a large tertiary referral center over two decades.
Ihlow, J., Gross, S., Neuendorff, N.R., Busack, L., Herneth, A., Singh, A., Schwarz, M., Flörcken, A., Anagnostopoulos, I., Türkmen, S., Burmeister, T., Blau, I.W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Westermann, J.
Journal of Geriatric Oncology 12
(4): 540-549.
May 2021
B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased.
Ihlow, J. ORCID: https://orcid.org/0000-0001-5484-1321, Michaelis, E., Greuel, S., Heynol, V., Lehmann, A., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Meinhardt, J., Miller, F., Herbst, H., Corman, V.M., Westermann, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Horst, D., von Brünneck, A.C. and Elezkurtaj, S.
International Journal of Infectious Diseases 103
: 628-635.
February 2021
MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari, F. ORCID: https://orcid.org/0000-0001-8440-9847, Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Ciolli Mattioli, C. ORCID: https://orcid.org/0000-0002-8499-1387, Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, Scholz, F. ORCID: https://orcid.org/0000-0002-0253-081X, Timm, L., Twamley, S., Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cellular and Molecular Life Sciences 78
(7): 3525-3542.
April 2021
iPSC-derived 2D and 3D models of mitochondrial disease reveal early defects in neuronal morphogenesis and identify intervention strategies.
Inak, G., Rybak, A. ORCID: https://orcid.org/0000-0002-1192-5290, Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072, Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Schuelke, M. ORCID: https://orcid.org/0000-0003-2824-3891 and Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952
[Dataset]
20 April 2021
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G., Rybak-Wolf, A. ORCID: https://orcid.org/0000-0002-1192-5290, Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072, Pentimalli, T.M. ORCID: https://orcid.org/0000-0002-8461-7918, Jüttner, R. ORCID: https://orcid.org/0000-0003-3565-0698, Glažar, P. ORCID: https://orcid.org/0000-0003-0842-0088, Uppal, K., Bottani, E. ORCID: https://orcid.org/0000-0003-1217-8722, Brunetti, D. ORCID: https://orcid.org/0000-0002-2740-9370, Secker, C. ORCID: https://orcid.org/0000-0002-7222-536X, Zink, A. ORCID: https://orcid.org/0000-0002-8489-6339, Meierhofer, D. ORCID: https://orcid.org/0000-0002-0170-868X, Henke, M.T. ORCID: https://orcid.org/0000-0001-6572-1667, Dey, M. ORCID: https://orcid.org/0000-0002-9987-575X, Ciptasari, U. ORCID: https://orcid.org/0000-0003-4577-3069, Mlody, B. ORCID: https://orcid.org/0000-0001-5184-1772, Hahn, T., Berruezo-Llacuna, M., Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793, Mayr, J.A. ORCID: https://orcid.org/0000-0001-6970-336X, Wortmann, S.B., Priller, J. ORCID: https://orcid.org/0000-0001-7596-0979, Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172, Jones, D.P., Mayatepek, E., Stenzel, W., Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Schuelke, M. ORCID: https://orcid.org/0000-0003-2824-3891 and Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952
Nature Communications 12
(1): 1929.
26 March 2021
Pantoea stewartii WceF is a glycan biofilm modifying enzyme with a bacteriophage tailspike-like fold.
Irmscher, T., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Gayk, I., Dunsing, V., Chiantia, S., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Barbirz, S.
Journal of Biological Chemistry 296
: 100286.
2021
The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-mediated immune responses.
Jongsma, M.L.M., de Waard, A.A., Raaben, M., Zhang, T., Cabukusta, B., Platzer, R., Blomen, V.A., Xagara, A., Verkerk, T., Bliss, S., Kong, X., Gerke, C., Janssen, L., Stickel, E., Holst, S., Plomp, R., Mulder, A., Ferrone, S., Claas, F.H.J., Heemskerk, M.H.M, Griffioen, M., Halenius, A., Overkleeft, H., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Wuhrer, M., Brummelkamp, T.R., Neefjes, J. and Spaapen, R.M.
Immunity 54
(1): 132-150.e9.
12 January 2021
Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.
Kamdem, N., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Kovalskyy, D. ORCID: https://orcid.org/0000-0002-1143-8724, Platonov, M.O., Balinskyi, O., Kreuchwig, A., Saupe, J. ORCID: https://orcid.org/0000-0003-4110-9881, Fang, L., Diehl, A., Schmieder, P. ORCID: https://orcid.org/0000-0001-9968-9327, Krause, G., Rademann, J. ORCID: https://orcid.org/0000-0001-6678-3165, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Oschkinat, H. ORCID: https://orcid.org/0000-0002-4384-9544
Magnetic Resonance 2
(1): 355-374.
2 June 2021
Adjuvants and vaccines used in allergen-specific immunotherapy induce neutrophil extracellular traps.
Karacs, J., Reithofer, M. ORCID: https://orcid.org/0000-0003-2845-1826, Kitzmüller, C. ORCID: https://orcid.org/0000-0002-3829-8020, Kraller, M., Schmalz, S. ORCID: https://orcid.org/0000-0003-4841-4942, Bleichert, S. ORCID: https://orcid.org/0000-0002-3054-1751, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Stockinger, H. ORCID: https://orcid.org/0000-0001-6404-4430, Bohle, B. and Jahn-Schmid, B. ORCID: https://orcid.org/0000-0002-7979-6667
Vaccines 9
(4): 321.
1 April 2021
Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide - an international collaborative study.
Kayser, S., Schlenk, R.F., Lebon, D., Carre, M., Götze, K.S., Stölzel, F., Berceanu, A., Schäfer-Eckart, K., Peterlin, P., Hicheri, Y., Rahme, R., Raffoux, E., Chermat, F., Krause, S.W., Aulitzky, W.E., Rigaudeau, S., Noppeney, R., Berthon, C., Görner, M., Jost, E., Carassou, P., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Orvain, C., Braun, T., Saillard, C., Arar, A., Kunzmann, V., Wemeau, M., De Wit, M., Niemann, D., Bonmati, C., Schwänen, C., Abraham, J., Aljijakli, A., Haiat, S., Krämer, A., Reichle, A., Gnadler, M., Willekens, C., Spiekermann, K., Hiddemann, W., Müller-Tidow, C., Thiede, C., Röllig, C., Serve, H., Bornhäuser, M., Baldus, C.D., Lengfelder, E., Fenaux, P., Platzbecker, U. and Adès, L.
Haematologica 106
(12): 3100-3106.
December 2021
Profiling of sub-lethal in vitro effects of multi-walled carbon nanotubes reveals changes in chemokines and chemokine receptors.
Keshavan, S. ORCID: https://orcid.org/0000-0002-2403-4083, Andón, F.T. ORCID: https://orcid.org/0000-0001-9235-1278, Gallud, A. ORCID: https://orcid.org/0000-0003-0283-4028, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Reinert, K., Tran, L. and Fadeel, B. ORCID: https://orcid.org/0000-0001-5559-8482
Nanomaterials 11
(4): 883.
30 March 2021
Subclone eradication analysis identifies targets for enhanced cancer therapy and reveals L1 retrotransposition as a dynamic source of cancer heterogeneity.
Ketola, K., Kaljunen, H., Taavitsainen, S., Kaarijärvi, R., Järvelä, E. ORCID: https://orcid.org/0000-0002-5249-2508, Rodriguez Martin, B., Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Woodcock, D.J., Tubio, J., Wedge, D.C. ORCID: https://orcid.org/0000-0002-7572-3196, Nykter, M. and Bova, G.S. ORCID: https://orcid.org/0000-0003-1639-3104
Cancer Research 81
(19): 4901-4909.
October 2021
Characterization and modulation of anti- αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells.
Kierkels, G.J.J., van Diest, E., Hernández-López, P., Scheper, W., de Bruin, A.C.M., Frijlink, E., Aarts-Riemens, T., van Dooremalen, S.F.J., Beringer, D.X., Oostvogels, R., Kramer, L., Straetemans, T., Uckert, W., Sebestyén, Z. and Kuball, J.
Molecular Therapy - Methods and Clinical Development 22
(10): 388-400.
10 September 2021
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky, D.J., Abdel-Aziz, A.K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M.H., Abudu, Y.P., Acevedo-Arozena, A., Adamopoulos, I.E., Adeli, K., Adolph, T.E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B.B., Agnello, M., Agostinis, P., Agrewala, J.N., Agrotis, A., Aguilar, P.V., Ahmad, S.T., Ahmed, Z.M., Ahumada-Castro, U., Aits, S., Aizawa, S., Akkoc, Y., Akoumianaki, T., Akpinar, H.A., Al-Abd, A.M., Al-Akra, L., Al-Gharaibeh, A., Alaoui-Jamali, M.A., Alberti, S., Alcocer-Gómez, E., Alessandri, C., Ali, M., Alim Al-Bari, M.A., Aliwaini, S., Alizadeh, J., Almacellas, E., Almasan, A., Alonso, A., Alonso, G.D., Altan-Bonnet, N., Altieri, D.C., Álvarez, E.M.C., Alves, S., Alves da Costa, C., Alzaharna, M.M., Amadio, M., Amantini, C., Amaral, C., Ambrosio, S., Amer, A.O., Ammanathan, V., An, Z., Andersen, S.U., Andrabi, S.A., Andrade-Silva, M., Andres, A.M., Angelini, S., Ann, D., Anozie, U.C., Ansari, M.Y., Antas, P., Antebi, A., Antón, Z., Anwar, T., Apetoh, L., Apostolova, N., Araki, T., Araki, Y., Arasaki, K., Araújo, W.L., Araya, J., Arden, C., Arévalo, M.A., Arguelles, S., Arias, E., Arikkath, J., Arimoto, H., Ariosa, A.R., Armstrong-James, D., Arnauné-Pelloquin, L., Aroca, A., Arroyo, D.S., Arsov, I., Artero, R., Asaro, D.M.L., Aschner, M., Ashrafizadeh, M., Ashur-Fabian, O., Atanasov, A.G., Au, A.K., Auberger, P., Auner, H.W., Aurelian, L., Autelli, R., Avagliano, L., Ávalos, Y., Aveic, S., Aveleira, C.A., Avin-Wittenberg, T., Aydin, Y., Ayton, S., Ayyadevara, S., Azzopardi, M., Baba, M.u, Backer, J.M., Backues, S.K., Bae, D.H., Bae, O.N., Bae, S.H., Baehrecke, E.H., Baek, A., Baek, S.H., Baek, S.H., Bagetta, G., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X., Bai, Y., Bairagi, N., Baksi, S., Balbi, T., Baldari, C.T., Balduini, W., Ballabio, A., Ballester, M., Balazadeh, S., Balzan, R., Bandopadhyay, R., Banerjee, S., Banerjee, S., Bánréti, A., Bao, Y., Baptista, M.S., Baracca, A., Barbati, C., Bargiela, A., Barilà, D., Barlow, P.G., Barmada, S.J., Barreiro, E., Barreto, G.E., Bartek, J., Bartel, B., Bartolome, A., Barve, G.R., Basagoudanavar, S.H., Bassham, D.C., Bast, R.C., Basu, A., Batoko, H., Batten, I., Baulieu, E.E., Baumgarner, B.L., Bayry, J., Beale, R., Beau, I., Beaumatin, F., Bechara, L.R.G., Beck, G.R., Beers, M.F., Begun, J., Behrends, C., Behrens, G.M.N., Bei, R., Bejarano, E., Bel, S., Behl, C., Belaid, A., Belgareh-Touzé, N., Bellarosa, C., Belleudi, F., Belló Pérez, M., Bello-Morales, R., Beltran, J.S.O., Beltran, S., Benbrook, D.M., Bendorius, M., Benitez, B.A., Benito-Cuesta, I., Bensalem, J., Berchtold, M.W., Berezowska, S., Bergamaschi, D., Bergami, M., Bergmann, A., Berliocchi, L., Berlioz-Torrent, C., Bernard, A., Berthoux, L., Besirli, C.G., Besteiro, S., Betin, V.M., Beyaert, R., Bezbradica, J.S., Bhaskar, K., Bhatia-Kissova, I., Bhattacharya, R., Bhattacharya, S., Bhattacharyya, S., Bhuiyan, M.S., Bhutia, S.K., Bi, L., Bi, X., Biden, T.J., Bijian, K., Billes, V.A., Binart, N., Bincoletto, C., Birgisdottir, A.B., Bjorkoy, G., Blanco, G., Blas-Garcia, A., Blasiak, J., Blomgran, R., Blomgren, K., Blum, J.S., Boada-Romero, E., Boban, M., Boesze-Battaglia, K., Boeuf, P., Boland, B., Bomont, P., Bonaldo, P., Bonam, S.R., Bonfili, L., Bonifacino, J.S., Boone, B.A., Bootman, M.D., Bordi, M., Borner, C., Bornhauser, B.C., Borthakur, G., Bosch, J., Bose, S., Botana, L.M., Botas, J., Boulanger, C.M., Boulton, M.E., Bourdenx, M., Bourgeois, B., Bourke, N.M., Bousquet, G., Boya, P., Bozhkov, P.V., Bozi, L.H.M., Bozkurt, T.O., Brackney, D.E., Brandts, C.H., Braun, R.J., Braus, G.H., Bravo-Sagua, R., Bravo-San Pedro, J.M., Brest, P., Bringer, M.A., Briones-Herrera, A., Broaddus, V.C., Brodersen, P., Brodsky, J.L., Brody, S.L., Bronson, P.G., Bronstein, J.M., Brown, C.N., Brown, R.E., Brum, P.C., Brumell, J.H., Brunetti-Pierri, N., Bruno, D., Bryson-Richardson, R.J., Bucci, C., Buchrieser, C., Bueno, M., Buitrago-Molina, L.E., Buraschi, S., Buch, S., Buchan, J.R., Buckingham, E.M., Budak, H., Budini, M., Bultynck, G., Burada, F., Burgoyne, J.R., Burón, M.I., Bustos, V., Büttner, S., Butturini, E., Byrd, A., Cabas, I., Cabrera-Benitez, S., Cadwell, K., Cai, J., Cai, L., Cai, Q., Cairó, M., Calbet, J.A., Caldwell, G.A., Caldwell, K.A., Call, J.A., Calvani, R., Calvo, A.C., Calvo-Rubio Barrera, M., Camara, N.O., Camonis, J.H., Camougrand, N., Campanella, M., Campbell, E.M., Campbell-Valois, F.X., Campello, S., Campesi, I., Campos, J.C., Camuzard, O., Cancino, J., Candido de Almeida, D., Canesi, L., Caniggia, I., Canonico, B., Cantí, C., Cao, B., Caraglia, M., Caramés, B., Carchman, E.H., Cardenal-Muñoz, E., Cardenas, C., Cardenas, L., Cardoso, S.M., Carew, J.S., Carle, G.F., Carleton, G., Carloni, S., Carmona-Gutierrez, D., Carneiro, L.A., Carnevali, O., Carosi, J.M., Carra, S., Carrier, A., Carrier, L., Carroll, B., Carter, A.B., Carvalho, A.N., Casanova, M., Casas, C., Casas, J., Cassioli, C., Castillo, E.F., Castillo, K., Castillo-Lluva, S., Castoldi, F., Castori, M., Castro, A.F., Castro-Caldas, M., Castro-Hernandez, J., Castro-Obregon, S., Catz, S.D., Cavadas, C., Cavaliere, F., Cavallini, G., Cavinato, M., Cayuela, M.L., Cebollada Rica, P., Cecarini, V., Cecconi, F., Cechowska-Pasko, M., Cenci, S., Ceperuelo-Mallafré, V., Cerqueira, J.J., Cerutti, J.M., Cervia, D., Cetintas, V.B., Cetrullo, S., Chae, H.J., Chagin, A.S., Chai, C.Y., Chakrabarti, G., Chakrabarti, O., Chakraborty, T., Chakraborty, T., Chami, M., Chamilos, G., Chan, D.W., Chan, E.Y.W., Chan, E.D., Chan, H.Y.E., Chan, H.H., Chan, H., Chan, M.T.V., Chan, Y.S., Chandra, P.K., Chang, C.P., Chang, C., Chang, H.C., Chang, K., Chao, J., Chapman, T., Charlet-Berguerand, N., Chatterjee, S., Chaube, S.K., Chaudhary, A., Chauhan, S., Chaum, E., Checler, F., Cheetham, M.E., Chen, C.S., Chen, G.C., Chen, J.F., Chen, L.L., Chen, L., Chen, L., Chen, M., Chen, M.K., Chen, N., Chen, Q., Chen, R.H., Chen, S., Chen, W., Chen, W., Chen, X.M., Chen, X.W., Chen, X., Chen, Y., Chen, Y.G., Chen, Y., Chen, Y., Chen, Y.J., Chen, Y.Q., Chen, Z.S., Chen, Z., Chen, Z.H., Chen, Z.J., Chen, Z., Cheng, H., Cheng, J., Cheng, S.Y., Cheng, W., Cheng, X., Cheng, X.T., Cheng, Y., Cheng, Z., Chen, Z., Cheong, H., Cheong, J.K., Chernyak, B.V., Cherry, S., Cheung, C.F.R., Cheung, C.H.A., Cheung, K.H., Chevet, E., Chi, R.J., Chiang, A.K.S., Chiaradonna, F., Chiarelli, R., Chiariello, M., Chica, N., Chiocca, S., Chiong, M., Chiou, S.H., Chiramel, A.I., Chiurchiù, V., Cho, D.H., Choe, S.K., Choi, A.M.K., Choi, M.E., Choudhury, K.R., Chow, N.S., Chu, C.T., Chua, J.P., Chua, J.J.E., Chung, H., Chung, K.P., Chung, S., Chung, S.H., Chung, Y.L., Cianfanelli, V., Ciechomska, I.A., Cifuentes, M., Cinque, L., Cirak, S., Cirone, M., Clague, M.J., Clarke, R., Clementi, E., Coccia, E.M., Codogno, P., Cohen, E., Cohen, M.M, Colasanti, T., Colasuonno, F., Colbert, R.A., Colell, A., Čolić, M., Coll, N.S., Collins, M.O., Colombo, M.I., Colón-Ramos, D.A., Combaret, L., Comincini, S., Cominetti, M.R., Consiglio, A., Conte, A., Conti, F., Contu, V.R., Cookson, M.R., Coombs, K.M., Coppens, I., Corasaniti, M.T., Corkery, D.P., Cordes, N., Cortese, K., Costa, M.D.C., Costantino, S., Costelli, P., Coto-Montes, A., Crack, P.J., Crespo, J.L., Criollo, A., Crippa, V., Cristofani, R., Csizmadia, T., Cuadrado, A., Cui, B., Cui, J., Cui, Y., Cui, Y., Culetto, E., Cumino, A.C., Cybulsky, A.V., Czaja, M.J., Czuczwar, S.J., D'Adamo, S., D'Amelio, M., D'Arcangelo, D., D'Lugos, A.C., D'Orazi, G., da Silva, J.A., Dafsari, H.S., Dagda, R.K., Dagdas, Y., Daglia, M., Dai, X., Dai, Y., Dai, Y., Dal Col, J., Dalhaimer, P., Dalla Valle, L., Dallenga, T., Dalmasso, G., Damme, M., Dando, I., Dantuma, N.P., Darling, A.L., Das, H., Dasarathy, S., Dasari, S.K., Dash, S., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Dauphinee, A.N., Davies, J.S., Dávila, V.A., Davis, R.J., Davis, T., Dayalan Naidu, S., De Amicis, F., De Bosscher, K., De Felice, F., De Franceschi, L., De Leonibus, C., de Mattos Barbosa, M.G., De Meyer, G.R.Y., De Milito, A., De Nunzio, C., De Palma, C., De Santi, M., De Virgilio, C., De Zio, D., Debnath, J., DeBosch, B.J., Decuypere, J.P., Deehan, M.A., Deflorian, G., DeGregori, J., Dehay, B., Del Rio, G., Delaney, J.R., Delbridge, L.M.D., Delorme-Axford, E., Delpino, M.V., Demarchi, F., Dembitz, V., Demers, N.D., Deng, H., Deng, Z., Dengjel, J., Dent, P., Denton, D., DePamphilis, M.L., Der, C.J., Deretic, V., Descoteaux, A., Devis, L., Devkota, S., Devuyst, O., Dewson, G., Dharmasivam, M., Dhiman, R., di Bernardo, D., Di Cristina, M., Di Domenico, F., Di Fazio, P., Di Fonzo, A., Di Guardo, G., Di Guglielmo, G.M., Di Leo, L., Di Malta, C., Di Nardo, A., Di Rienzo, M., Di Sano, F., Diallinas, G., Diao, J., Diaz-Araya, G., Díaz-Laviada, I., Dickinson, J.M., Diederich, M., Dieudé, M., Dikic, I., Ding, S., Ding, W.X., Dini, L., Dinić, J., Dinic, M., Dinkova-Kostova, A.T., Dionne, M.S., Distler, J.H.W., Diwan, A., Dixon, I.M.C., Djavaheri-Mergny, M., Dobrinski, I., Dobrovinskaya, O., Dobrowolski, R., Dobson, R.C.J., Đokić, J., Dokmeci Emre, S., Donadelli, M., Dong, B., Dong, X., Dong, Z., Dorn Ii, G.W., Dotsch, V., Dou, H., Dou, J., Dowaidar, M., Dridi, S., Drucker, L., Du, A., Du, C., Du, G., Du, H.N., Du, L.L., du Toit, A., Duan, S.B., Duan, X., Duarte, S.P., Dubrovska, A., Dunlop, E.A., Dupont, N., Durán, R.V., Dwarakanath, B.S., Dyshlovoy, S.A., Ebrahimi-Fakhari, D., Eckhart, L., Edelstein, C.L., Efferth, T., Eftekharpour, E., Eichinger, L., Eid, N., Eisenberg, T., Eissa, N.T., Eissa, S., Ejarque, M., El Andaloussi, A., El-Hage, N., El-Naggar, S., Eleuteri, A.M., El-Shafey, E.S., Elgendy, M., Eliopoulos, A.G., Elizalde, M.M., Elks, P.M., Elsasser, H.P., Elsherbiny, E.S., Emerling, B.M., Emre, N.C.T., Eng, C.H., Engedal, N., Engelbrecht, A.M., Engelsen, A.S.T., Enserink, J.M., Escalante, R., Esclatine, A., Escobar-Henriques, M., Eskelinen, E.L., Espert, L., Eusebio, M.O., Fabrias, G., Fabrizi, C., Facchiano, A., Facchiano, F., Fadeel, B., Fader, C., Faesen, A.C., Fairlie, W.D., Falcó, A., Falkenburger, B.H., Fan, D., Fan, J., Fan, Y., Fang, E.F., Fang, Y., Fang, Y., Fanto, M., Farfel-Becker, T., Faure, M., Fazeli, G., Fedele, A.O., Feldman, A.M., Feng, D., Feng, J., Feng, L., Feng, Y., Feng, Y., Feng, W., Fenz Araujo, T., Ferguson, T.A., Fernández, A.F., Fernandez-Checa, J.C., Fernández-Veledo, S., Fernie, A.R., Ferrante, A.W., Ferraresi, A., Ferrari, M.F., Ferreira, J.C.B., Ferro-Novick, S., Figueras, A., Filadi, R., Filigheddu, N., Filippi-Chiela, E., Filomeni, G., Fimia, G.M., Fineschi, V., Finetti, F., Finkbeiner, S., Fisher, E.A., Fisher, P.B., Flamigni, F., Fliesler, S.J., Flo, T.H., Florance, I., Florey, O., Florio, T., Fodor, E., Follo, C., Fon, E.A., Forlino, A., Fornai, F., Fortini, P., Fracassi, A., Fraldi, A., Franco, B., Franco, R., Franconi, F., Frankel, L.B., Friedman, S.L., Fröhlich, L.F., Frühbeck, G., Fuentes, J.M., Fujiki, Y., Fujita, N., Fujiwara, Y., Fukuda, M., Fulda, S., Furic, L., Furuya, N., Fusco, C., Gack, M.U., Gaffke, L., Galadari, S., Galasso, A., Galindo, M.F., Gallolu Kankanamalage, S., Galluzzi, L., Galy, V., Gammoh, N., Gan, B., Ganley, I.G., Gao, F., Gao, H., Gao, M., Gao, P., Gao, S.J., Gao, W., Gao, X., Garcera, A., Garcia, M.N., Garcia, V.E., García-Del Portillo, F., Garcia-Escudero, V., Garcia-Garcia, A., Garcia-Macia, M., García-Moreno, D., Garcia-Ruiz, C., García-Sanz, P., Garg, A.D., Gargini, R., Garofalo, T., Garry, R.F., Gassen, N.C., Gatica, D., Ge, L., Ge, W., Geiss-Friedlander, R., Gelfi, C., Genschik, P., Gentle, I.E., Gerbino, V., Gerhardt, C., Germain, K., Germain, M., Gewirtz, D.A., Ghasemipour Afshar, E., Ghavami, S., Ghigo, A., Ghosh, M., Giamas, G., Giampietri, C., Giatromanolaki, A., Gibson, G.E., Gibson, S.B., Ginet, V., Giniger, E., Giorgi, C., Girao, H., Girardin, S.E., Giridharan, M., Giuliano, S., Giulivi, C., Giuriato, S., Giustiniani, J., Gluschko, A., Goder, V., Goginashvili, A., Golab, J., Goldstone, D.C., Golebiewska, A., Gomes, L.R., Gomez, R., Gómez-Sánchez, R., Gomez-Puerto, M.C., Gomez-Sintes, R., Gong, Q., Goni, F.M., González-Gallego, J., Gonzalez-Hernandez, T., Gonzalez-Polo, R.A., Gonzalez-Reyes, J.A., González-Rodríguez, P., Goping, I.S., Gorbatyuk, M.S., Gorbunov, N.V., Görgülü, K., Gorojod, R.M., Gorski, S.M., Goruppi, S., Gotor, C., Gottlieb, R.A., Gozes, I., Gozuacik, D., Graef, M., Gräler, M.H., Granatiero, V., Grasso, D., Gray, J.P., Green, D.R., Greenhough, A., Gregory, S.L., Griffin, E.F., Grinstaff, M.W., Gros, F., Grose, C., Gross, A.S., Gruber, F., Grumati, P., Grune, T., Gu, X., Guan, J.L., Guardia, C.M., Guda, K., Guerra, F., Guerri, C., Guha, P., Guillén, C., Gujar, S., Gukovskaya, A., Gukovsky, I., Gunst, J., Günther, A., Guntur, A.R., Guo, C., Guo, C., Guo, H., Guo, L.W., Guo, M., Gupta, P., Gupta, S.K., Gupta, S., Gupta, V.B., Gupta, V., Gustafsson, A.B., Gutterman, D.D., H B, R., Haapasalo, A., Haber, J.E., Hać, A., Hadano, S., Hafrén, A.J., Haidar, M., Hall, B.S., Halldén, G., Hamacher-Brady, A., Hamann, A., Hamasaki, M., Han, W., Hansen, M., Hanson, P.I., Hao, Z., Harada, M., Harhaji-Trajkovic, L., Hariharan, N., Haroon, N., Harris, J., Hasegawa, T., Hasima Nagoor, N., Haspel, J.A., Haucke, V., Hawkins, W.D., Hay, B.A., Haynes, C.M., Hayrabedyan, S.B., Hays, T.S., He, C., He, Q., He, R.R., He, Y.W., He, Y.Y., Heakal, Y., Heberle, A.M., Hejtmancik, J.F., Helgason, G.V., Henkel, V., Herb, M., Hergovich, A., Herman-Antosiewicz, A., Hernández, A., Hernandez, C., Hernandez-Diaz, S., Hernandez-Gea, V., Herpin, A., Herreros, J., Hervás, J.H., Hesselson, D., Hetz, C., Heussler, V.T., Higuchi, Y., Hilfiker, S., Hill, J.A., Hlavacek, W.S., Ho, E.A., Ho, I.H.T., Ho, P.W.L., Ho, S.L., Ho, W.Y., Hobbs, G.A., Hochstrasser, M., Hoet, P.H.M., Hofius, D., Hofman, P., Höhn, A., Holmberg, C.I., Hombrebueno, J.R., Yi-Ren Hong, C.W.H., Hooper, L.V., Hoppe, T., Horos, R., Hoshida, Y., Hsin, I.L., Hsu, H.Y., Hu, B., Hu, D., Hu, L.F., Hu, M.C., Hu, R., Hu, W., Hu, Y.C., Hu, Z.W., Hua, F., Hua, J., Hua, Y., Huan, C., Huang, C., Huang, C., Huang, C., Huang, C., Huang, H., Huang, K., Huang, M.L.H., Huang, R., Huang, S., Huang, T., Huang, X., Huang, Y.J., Huber, T.B., Hubert, V., Hubner, C.A., Hughes, S.M., Hughes, W.E., Humbert, M., Hummer, G., Hurley, J.H., Hussain, S., Hussain, S., Hussey, P.J., Hutabarat, M., Hwang, H.Y., Hwang, S., Ieni, A., Ikeda, F., Imagawa, Y., Imai, Y., Imbriano, C., Imoto, M., Inman, D.M., Inoki, K., Iovanna, J., Iozzo, R.V., Ippolito, G., Irazoqui, J.E., Iribarren, P., Ishaq, M., Ishikawa, M., Ishimwe, N., Isidoro, C., Ismail, N., Issazadeh-Navikas, S., Itakura, E., Ito, D., Ivankovic, D., Ivanova, S., Iyer, A.K.V., Izquierdo, J.M., Izumi, M., Jäättelä, M., Jabir, M.S., Jackson, W.T., Jacobo-Herrera, N., Jacomin, A.C., Jacquin, E., Jadiya, P., Jaeschke, H., Jagannath, C., Jakobi, A.J., Jakobsson, J., Janji, B., Jansen-Dürr, P., Jansson, P.J., Jantsch, J., Januszewski, S., Jassey, A., Jean, S., Jeltsch-David, H., Jendelova, P., Jenny, A., Jensen, T.E., Jessen, N., Jewell, J.L., Ji, J., Jia, L., Jia, R., Jiang, L., Jiang, Q., Jiang, R., Jiang, T., Jiang, X., Jiang, Y., Jimenez-Sanchez, M., Jin, E.J., Jin, F., Jin, H., Jin, L., Jin, L., Jin, M., Jin, S., Jo, E.K., Joffre, C., Johansen, T., Johnson, G.V.W., Johnston, S.A., Jokitalo, E., Jolly, M.K., Joosten, L.A.B., Jordan, J., Joseph, B., Ju, D., Ju, J.S., Ju, J., Juárez, E., Judith, D., Juhász, G., Jun, Y., Jung, C.H., Jung, S.C., Jung, Y.K., Jungbluth, H., Jungverdorben, J., Just, S., Kaarniranta, K., Kaasik, A., Kabuta, T., Kaganovich, D., Kahana, A., Kain, R., Kajimura, S., Kalamvoki, M., Kalia, M., Kalinowski, D.S., Kaludercic, N., Kalvari, I., Kaminska, J., Kaminskyy, V.O., Kanamori, H., Kanasaki, K., Kang, C., Kang, R., Kang, S.S., Kaniyappan, S., Kanki, T., Kanneganti, T.D., Kanthasamy, A.G., Kanthasamy, A., Kantorow, M., Kapuy, O., Karamouzis, M.V., Karim, M.D.R., Karmakar, P., Katare, R.G., Kato, M., Kaufmann, S.H.E., Kauppinen, A., Kaushal, G.P., Kaushik, S., Kawasaki, K., Kazan, K., Ke, P.Y., Keating, D.J., Keber, U., Kehrl, J.H., Keller, K.E., Keller, C.W., Kemper, J.K., Kenific, C.M., Kepp, O., Kermorgant, S., Kern, A., Ketteler, R., Keulers, T.G., Khalfin, B., Khalil, H., Khambu, B., Khan, S.Y., Khandelwal, V.K.M., Khandia, R., Kho, W., Khobrekar, N.V., Khuansuwan, S., Khundadze, M., Killackey, S.A., Kim, D., Kim, D.R., Kim, D.H., Kim, D.E., Kim, E.Y., Kim, E.K., Kim, H.R., Kim, H.S., Kim, H.R., Kim, J.H., Kim, J.K., Kim, J.H., Kim, J., Kim, J.H., Kim, K.I.I., Kim, P.K., Kim, S.J., Kimball, S.R., Kimchi, A., Kimmelman, A.C., Kimura, T., King, M.A., Kinghorn, K.J., Kinsey, C.G., Kirkin, V., Kirshenbaum, L.A., Kiselev, S.L., Kishi, S., Kitamoto, K., Kitaoka, Y., Kitazato, K., Kitsis, R.N., Kittler, J.T., Kjaerulff, O., Klein, P.S., Klopstock, T., Klucken, J., Knævelsrud, H., Knorr, R.L., Ko, B.C.B., Ko, F., Ko, J.L., Kobayashi, H., Kobayashi, S., Koch, I., Koch, J.C., Koenig, U., Kögel, D., Koh, Y.H., Koike, M., Kohlwein, S.D., Kocaturk, N.M., Komatsu, M., König, J., Kono, T., Kopp, B.T., Korcsmaros, T., Korkmaz, G., Korolchuk, V.I., Korsnes, M.S., Koskela, A., Kota, J., Kotake, Y., Kotler, M.L., Kou, Y., Koukourakis, M.I., Koustas, E., Kovacs, A.L., Kovács, T., Koya, D., Kozako, T., Kraft, C., Krainc, D., Krämer, H., Krasnodembskaya, A.D., Kretz-Remy, C., Kroemer, G., Ktistakis, N.T., Kuchitsu, K., Kuenen, S., Kuerschner, L., Kukar, T., Kumar, A., Kumar, A., Kumar, D., Kumar, D., Kumar, S., Kume, S., Kumsta, C., Kundu, C.N., Kundu, M., Kunnumakkara, A.B., Kurgan, L., Kutateladze, T.G., Kutlu, O., Kwak, S.A., Kwon, H.J., Kwon, T.K., Kwon, Y.T., Kyrmizi, I., La Spada, A., Labonté, P., Ladoire, S., Laface, I., Lafont, F., Lagace, D.C., Lahiri, V., Lai, Z., Laird, A.S., Lakkaraju, A., Lamark, T., Lan, S.H., Landajuela, A., Lane, D.J.R., Lane, J.D., Lang, C.H., Lange, C., Langel, Ü., Langer, R., Lapaquette, P., Laporte, J., LaRusso, N.F., Lastres-Becker, I., Lau, W.C.Y., Laurie, G.W., Lavandero, S., Law, B.Y.K., Law, H.K.W., Layfield, R., Le, W., Le Stunff, H., Leary, A.Y., Lebrun, J.J., Leck, L.Y.W., Leduc-Gaudet, J.P., Lee, C., Lee, C.P., Lee, D.H., Lee, E.B., Lee, E.F., Lee, G.M., Lee, H.J., Lee, H.K., Lee, J.M., Lee, J.S., Lee, J.A., Lee, J.Y., Lee, J.H., Lee, M., Lee, M.G., Lee, M.J., Lee, M.S., Lee, S.Y., Lee, S.J., Lee, S.Y., Lee, S.B., Lee, W.H., Lee, Y.R., Lee, Y.H., Lee, Y., Lefebvre, C., Legouis, R., Lei, Y.L., Lei, Y., Leikin, S., Leitinger, G., Lemus, L., Leng, S., Lenoir, O., Lenz, G., Lenz, H.J., Lenzi, P., León, Y., Leopoldino, A.M., Leschczyk, C., Leskelä, S., Letellier, E., Leung, C.T., Leung, P.S., Leventhal, J.S., Levine, B., Lewis, P.A., Ley, K., Li, B., Li, D.Q., Li, J., Li, J., Li, J., Li, K., Li, L., Li, M., Li, M., Li, M., Li, M., Li, M., Li, P.L., Li, M.Q., Li, Q., Li, S., Li, T., Li, W., Li, W., Li, X., Li, Y.P., Li, Y., Li, Z., Li, Z., Li, Z., Lian, J., Liang, C., Liang, Q., Liang, W., Liang, Y., Liang, Y.T., Liao, G., Liao, L., Liao, M., Liao, Y.F., Librizzi, M., Lie, P.P.Y., Lilly, M.A., Lim, H.J., Lima, T.R.R., Limana, F., Lin, C., Lin, C.W., Lin, D.S., Lin, F.C., Lin, J.D., Lin, K.M., Lin, K.H., Lin, L.T., Lin, P.H., Lin, Q., Lin, S., Lin, S.J., Lin, W., Lin, X., Lin, Y.X., Lin, Y.S., Linden, R., Lindner, P., Ling, S.C., Lingor, P., Linnemann, A.K., Liou, Y.C., Lipinski, M.M., Lipovšek, S., Lira, V.A., Lisiak, N., Liton, P.B., Liu, C., Liu, C.H., Liu, C.F., Liu, C.H., Liu, F., Liu, H., Liu, H.S., Liu, H.F., Liu, H., Liu, J., Liu, J., Liu, J., Liu, L., Liu, L., Liu, M., Liu, Q., Liu, W., Liu, W., Liu, X.H., Liu, X., Liu, X., Liu, X., Liu, X., Liu, Y., Liu, Y., Liu, Y., Liu, Y., Liu, Y., Livingston, J.A., Lizard, G., Lizcano, J.M., Ljubojevic-Holzer, S., LLeonart, M.E., Llobet-Navàs, D., Llorente, A., Lo, C.H., Lobato-Márquez, D., Long, Q., Long, Y.C., Loos, B., Loos, J.A., López, M.G., López-Doménech, G., López-Guerrero, J.A., López-Jiménez, A.T., López-Pérez, O., López-Valero, I., Lorenowicz, M.J., Lorente, M., Lorincz, P., Lossi, L., Lotersztajn, S., Lovat, P.E., Lovell, J.F., Lovy, A., Lőw, P., Lu, G., Lu, H., Lu, J.H., Lu, J.J., Lu, M., Lu, S., Luciani, A., Lucocq, J.M., Ludovico, P., Luftig, M.A., Luhr, M., Luis-Ravelo, D., Lum, J.J., Luna-Dulcey, L., Lund, A.H., Lund, V.K., Lünemann, J.D., Lüningschrör, P., Luo, H., Luo, R., Luo, S., Luo, Z., Luparello, C., Lüscher, B., Luu, L., Lyakhovich, A., Lyamzaev, K.G., Lystad, A.H., Lytvynchuk, L., Ma, A.C., Ma, C., Ma, M., Ma, N.F., Ma, Q.H., Ma, X., Ma, Y., Ma, Z., MacDougald, O.A., Macian, F., MacIntosh, G.C., MacKeigan, J.P., Macleod, K.F., Maday, S., Madeo, F., Madesh, M., Madl, T., Madrigal-Matute, J., Maeda, A., Maejima, Y., Magarinos, M., Mahavadi, P., Maiani, E., Maiese, K., Maiti, P., Maiuri, M.C., Majello, B., Major, M.B., Makareeva, E., Malik, F., Mallilankaraman, K., Malorni, W., Maloyan, A., Mammadova, N., Man, G.C.W., Manai, F., Mancias, J.D., Mandelkow, E.M., Mandell, M.A., Manfredi, A.A., Manjili, M.H., Manjithaya, R., Manque, P., Manshian, B.B., Manzano, R., Manzoni, C., Mao, K., Marchese, C., Marchetti, S., Marconi, A.M., Marcucci, F., Mardente, S., Mareninova, O.A., Margeta, M., Mari, M., Marinelli, S., Marinelli, O., Mariño, G., Mariotto, S., Marshall, R.S., Marten, M.R., Martens, S., Martin, A.P.J., Martin, K.R., Martin, S., Martin, S., Martín-Segura, A., Martín-Acebes, M.A., Martin-Burriel, I., Martin-Rincon, M., Martin-Sanz, P., Martina, J.A., Martinet, W., Martinez, A., Martinez, A., Martinez, J., Martinez Velazquez, M., Martinez-Lopez, N., Martinez-Vicente, M., Martins, D.O., Martins, J.O., Martins, W.K., Martins-Marques, T., Marzetti, E., Masaldan, S., Masclaux-Daubresse, C., Mashek, D.G., Massa, V., Massieu, L., Masson, G.R., Masuelli, L., Masyuk, A.I., Masyuk, T.V., Matarrese, P., Matheu, A., Matoba, S., Matsuzaki, S., Mattar, P., Matte, A., Mattoscio, D., Mauriz, J.L., Mauthe, M., Mauvezin, C., Maverakis, E., Maycotte, P., Mayer, J., Mazzoccoli, G., Mazzoni, C., Mazzulli, J.R., McCarty, N., McDonald, C., McGill, M.R., McKenna, S.L., McLaughlin, B.A., McLoughlin, F., McNiven, M.A., McWilliams, T.G., Mechta-Grigoriou, F., Medeiros, T.C., Medina, D.L., Megeney, L.Y., Megyeri, K., Mehrpour, M., Mehta, J.L., Meijer, A.J., Meijer, A.H., Mejlvang, J., Meléndez, A., Melk, A., Memisoglu, G., Mendes, A.F., Meng, D., Meng, F., Meng, T., Menna-Barreto, R., Menon, M.B., Mercer, C., Mercier, A.E., Mergny, J.L., Merighi, A., Merkley, S.D., Merla, G., Meske, V., Mestre, A.C., Metur, S.P., Meyer, C., Meyer, H., Mi, W., Mialet-Perez, J., Miao, J., Micale, L., Miki, Y., Milan, E., Milczarek, M., Miller, D.L., Miller, S.I., Miller, S., Millward, S.W., Milosevic, I., Minina, E.A., Mirzaei, H., Mirzaei, H.R., Mirzaei, M., Mishra, A., Mishra, N., Mishra, P.K., Misirkic Marjanovic, M., Misasi, R., Misra, A., Misso, G., Mitchell, C., Mitou, G., Miura, T., Miyamoto, S., Miyazaki, M., Miyazaki, M., Miyazaki, T., Miyazawa, K., Mizushima, N., Mogensen, T.H., Mograbi, B., Mohammadinejad, R., Mohamud, Y., Mohanty, A., Mohapatra, S., Möhlmann, T., Mohmmed, A., Moles, A., Moley, K.H., Molinari, M., Mollace, V., Møller, A.B., Mollereau, B., Mollinedo, F., Montagna, C., Monteiro, M.J., Montella, A., Montes, L.R., Montico, B., Mony, V.K., Monzio Compagnoni, G., Moore, M.N., Moosavi, M.A., Mora, A.L., Mora, M., Morales-Alamo, D., Moratalla, R., Moreira, P.I., Morelli, E., Moreno, S., Moreno-Blas, D., Moresi, V., Morga, B., Morgan, A.H., Morin, F., Morishita, H., Moritz, O.L., Moriyama, M., Moriyasu, Y., Morleo, M., Morselli, E., Moruno-Manchon, J.F., Moscat, J., Mostowy, S., Motori, E., Moura, A.F., Moustaid-Moussa, N., Mrakovcic, M., Muciño-Hernández, G., Mukherjee, A., Mukhopadhyay, S., Mulcahy Levy, J.M., Mulero, V., Muller, S., Münch, C., Munjal, A., Munoz-Canoves, P., Muñoz-Galdeano, T., Münz, C., Murakawa, T., Muratori, C., Murphy, B.M., Murphy, J.P., Murthy, A., Myöhänen, T.T., Mysorekar, I.U., Mytych, J., Nabavi, S.M., Nabissi, M., Nagy, P., Nah, J., Nahimana, A., Nakagawa, I., Nakamura, K., Nakatogawa, H., Nandi, S.S., Nanjundan, M., Nanni, M., Napolitano, G., Nardacci, R., Narita, M., Nassif, M., Nathan, I., Natsumeda, M., Naude, R.J., Naumann, C., Naveiras, O., Navid, F., Nawrocki, S.T., Nazarko, T.Y., Nazio, F., Negoita, F., Neill, T., Neisch, A.L., Neri, L.M., Netea, M.G., Neubert, P., Neufeld, T.P., Neumann, D., Neutzner, A., Newton, P.T., Ney, P.A., Nezis, I.P., Ng, C.C.W., Ng, T.B., Nguyen, H.T.T., Nguyen, L.T., Ni, H.M., Ní Cheallaigh, C., Ni, Z., Nicolao, M.C., Nicoli, F., Nieto-Diaz, M., Nilsson, P., Ning, S., Niranjan, R., Nishimune, H., Niso-Santano, M., Nixon, R.A., Nobili, A., Nobrega, C., Noda, T., Nogueira-Recalde, U., Nolan, T.M., Nombela, I., Novak, I., Novoa, B., Nozawa, T., Nukina, N., Nussbaum-Krammer, C., Nylandsted, J., O'Donovan, T.R., O'Leary, S.M., O'Rourke, E.J., O'Sullivan, M.P., O'Sullivan, T.E., Oddo, S., Oehme, I., Ogawa, M., Ogier-Denis, E., Ogmundsdottir, M.H., Ogretmen, B., Oh, G.T., Oh, S.H., Oh, Y.J., Ohama, T., Ohashi, Y., Ohmuraya, M., Oikonomou, V., Ojha, R., Okamoto, K., Okazawa, H., Oku, M., Oliván, S., Oliveira, J.M.A., Ollmann, M., Olzmann, J.A., Omari, S., Omary, M.B., Önal, G., Ondrej, M., Ong, S.B., Ong, S.G., Onnis, A., Orellana, J.A., Orellana-Muñoz, S., Ortega-Villaizan, M.D.M., Ortiz-Gonzalez, X.R., Ortona, E., Osiewacz, H.D., Osman, A.H.K., Osta, R., Otegui, M.S., Otsu, K., Ott, C., Ottobrini, L., Ou, J.H.J., Outeiro, T.F., Oynebraten, I., Ozturk, M., Pagès, G., Pahari, S., Pajares, M., Pajvani, U.B., Pal, R., Paladino, S., Pallet, N., Palmieri, M., Palmisano, G., Palumbo, C., Pampaloni, F., Pan, L., Pan, Q., Pan, W:, Pan, X., Panasyuk, G., Pandey, R., Pandey, U.B., Pandya, V., Paneni, F., Pang, S.Y., Panzarini, E., Papademetrio, D.L., Papaleo, E., Papinski, D., Papp, D., Park, E.C., Park, H.T., Park, J.M., Park, J.I., Park, J.T., Park, J., Park, S.C., Park, S.Y., Parola, A.H., Parys, J.B., Pasquier, A., Pasquier, B., Passos, J.F., Pastore, N., Patel, H.H., Patschan, D., Pattingre, S., Pedraza-Alva, G., Pedraza-Chaverri, J., Pedrozo, Z., Pei, G., Pei, J., Peled-Zehavi, H., Pellegrini, J.M., Pelletier, J., Peñalva, M.A., Peng, D., Peng, Y., Penna, F., Pennuto, M., Pentimalli, F., Pereira, C.M.F., Pereira, G.J.S., Pereira, L.C., Pereira de Almeida, L., Perera, N.D., Pérez-Lara, A., Perez-Oliva, A.B., Pérez-Pérez, M.E., Periyasamy, P., Perl, A., Perrotta, C., Perrotta, I., Pestell, R.G., Petersen, M., Petrache, I., Petrovski, G., Pfirrmann, T., Pfister, A.S., Philips, J.A., Pi, H., Picca, A., Pickrell, A.M., Picot, S., Pierantoni, G.M., Pierdominici, M., Pierre, P., Pierrefite-Carle, V., Pierzynowska, K., Pietrocola, F., Pietruczuk, M., Pignata, C., Pimentel-Muiños, F.X., Pinar, M., Pinheiro, R.O., Pinkas-Kramarski, R., Pinton, P., Pircs, K., Piya, S., Pizzo, P., Plantinga, T.S., Platta, H.W., Plaza-Zabala, A., Plomann, M., Plotnikov, E.Y., Plun-Favreau, H., Pluta, R., Pocock, R., Pöggeler, S., Pohl, C., Poirot, M., Poletti, A., Ponpuak, M., Popelka, H., Popova, B., Porta, H., Porte Alcon, S., Portilla-Fernandez, E., Post, M., Potts, M.B., Poulton, J., Powers, T., Prahlad, V., Prajsnar, T.K., Praticò, D., Prencipe, R., Priault, M., Proikas-Cezanne, T., Promponas, V.J., Proud, C.G., Puertollano, R., Puglielli, L., Pulinilkunnil, T., Puri, D., Puri, R., Puyal, J., Qi, X., Qi, Y., Qian, W., Qiang, L., Qiu, Y., Quadrilatero, J., Quarleri, J., Raben, N., Rabinowich, H., Ragona, D., Ragusa, M.J., Rahimi, N., Rahmati, M., Raia, V., Raimundo, N., Rajasekaran, N.S., Ramachandra Rao, S., Rami, A., Ramírez-Pardo, I., Ramsden, D.B., Randow, F., Rangarajan, P.N., Ranieri, D., Rao, H., Rao, L., Rao, R., Rathore, S., Ratnayaka, J.A., Ratovitski, E.A., Ravanan, P., Ravegnini, G., Ray, S.K., Razani, B., Rebecca, V., Reggiori, F., Régnier-Vigouroux, A., Reichert, A.S., Reigada, D., Reiling, J.H., Rein, T., Reipert, S., Rekha, R.S., Ren, H., Ren, J., Ren, W., Renault, T., Renga, G., Reue, K., Rewitz, K., Ribeiro de Andrade Ramos, B., Riazuddin, S.A., Ribeiro-Rodrigues, T.M., Ricci, J.E., Ricci, R., Riccio, V., Richardson, D.R., Rikihisa, Y., Risbud, M.V., Risueño, R.M., Ritis, K., Rizza, S., Rizzuto, R., Roberts, H.C., Roberts, L.D., Robinson, K.J., Roccheri, M.C., Rocchi, S., Rodney, G.G., Rodrigues, T., Rodrigues Silva, V.R., Rodriguez, A., Rodriguez-Barrueco, R., Rodriguez-Henche, N., Rodriguez-Rocha, H., Roelofs, J., Rogers, R.S., Rogov, V.V., Rojo, A.I., Rolka, K., Romanello, V., Romani, L., Romano, A., Romano, P.S., Romeo-Guitart, D., Romero, L.C., Romero, M., Roney, J.C., Rongo, C., Roperto, S., Rosenfeldt, M.T., Rosenstiel, P., Rosenwald, A.G., Roth, K.A., Roth, L., Roth, S., Rouschop, K.M.A., Roussel, B.D., Roux, S., Rovere-Querini, P., Roy, A., Rozieres, A., Ruano, D., Rubinsztein, D.C., Rubtsova, M.P., Ruckdeschel, K., Ruckenstuhl, C., Rudolf, E., Rudolf, R., Ruggieri, A., Ruparelia, A.A., Rusmini, P., Russell, R.R., Russo, G.L., Russo, M., Russo, R., Ryabaya, O.O., Ryan, K.M., Ryu, K.Y., Sabater-Arcis, M., Sachdev, U., Sacher, M., Sachse, C., Sadhu, A., Sadoshima, J., Safren, N., Saftig, P., Sagona, A.P., Sahay, G., Sahebkar, A., Sahin, M., Sahin, O., Sahni, S., Saito, N., Saito, S., Saito, T., Sakai, R., Sakai, Y., Sakamaki, J.I., Saksela, K., Salazar, G., Salazar-Degracia, A., Salekdeh, G.H., Saluja, A.K., Sampaio-Marques, B., Sanchez, M.C., Sanchez-Alcazar, J.A., Sanchez-Vera, V., Sancho-Shimizu, V., Sanderson, J.T., Sandri, M., Santaguida, S., Santambrogio, L., Santana, M.M., Santoni, G., Sanz, A., Sanz, P., Saran, S., Sardiello, M., Sargeant, T.J., Sarin, A., Sarkar, C., Sarkar, S., Sarrias, M.R., Sarkar, S., Sarmah, D.T., Sarparanta, J., Sathyanarayan, A., Sathyanarayanan, R., Scaglione, K.M., Scatozza, F., Schaefer, L., Schafer, Z.T., Schaible, U.E., Schapira, A.H.V., Scharl, M., Schatzl, H.M., Schein, C.H., Scheper, W., Scheuring, D., Schiaffino, M.V., Schiappacassi, M., Schindl, R., Schlattner, U., Schmidt, O., Schmitt, R., Schmidt, S.D., Schmitz, I., Schmukler, E., Schneider, A., Schneider, B.E., Schober, R., Schoijet, A.C., Schott, M.B., Schramm, M., Schröder, B., Schuh, K., Schüller, C., Schulze, R.L., Schürmanns, L., Schwamborn, J.C., Schwarten, M., Scialo, F., Sciarretta, S., Scott, M.J., Scotto, K.W., Scovassi, A.I., Scrima, A., Scrivo, A., Sebastian, D., Sebti, S., Sedej, S., Segatori, L., Segev, N., Seglen, P.O., Seiliez, I., Seki, E., Selleck, S.B., Sellke, F.W., Selsby, J.T., Sendtner, M., Senturk, S., Seranova, E., Sergi, C., Serra-Moreno, R., Sesaki, H., Settembre, C., Setty, S.R.G., Sgarbi, G., Sha, O., Shacka, J.J., Shah, J.A., Shang, D., Shao, C., Shao, F., Sharbati, S., Sharkey, L.M., Sharma, D., Sharma, G., Sharma, K., Sharma, P., Sharma, S., Shen, H.M., Shen, H., Shen, J., Shen, M., Shen, W., Shen, Z., Sheng, R., Sheng, Z., Sheng, Z.H., Shi, J., Shi, X., Shi, Y.H., Shiba-Fukushima, K., Shieh, J.J., Shimada, Y., Shimizu, S., Shimozawa, M., Shintani, T., Shoemaker, C.J., Shojaei, S., Shoji, I., Shravage, B.V., Shridhar, V., Shu, C.W., Shu, H.B., Shui, K., Shukla, A.K., Shutt, T.E., Sica, V., Siddiqui, A., Sierra, A., Sierra-Torre, V., Signorelli, S., Sil, P., Silva, B.J.A., Silva, J.D., Silva-Pavez, E., Silvente-Poirot, S., Simmonds, R.E., Simon, A.K. ORCID: https://orcid.org/0000-0002-4077-7995, Simon, H.U., Simons, M., Singh, A., Singh, L.P., Singh, R., Singh, S.V., Singh, S.K., Singh, S.B., Singh, S., Singh, S.P., Sinha, D., Sinha, R.A., Sinha, S., Sirko, A., Sirohi, K., Sivridis, E.L., Skendros, P., Skirycz, A., Slaninová, I., Smaili, S.S., Smertenko, A., Smith, M.D., Soenen, S.J., Sohn, E.J., Sok, S.P.M., Solaini, G., Soldati, T., Soleimanpour, S.A., Soler, R.M., Solovchenko, A., Somarelli, J.A., Sonawane, A., Song, F., Song, H.K., Song, J.X., Song, K., Song, Z., Soria, L.R., Sorice, M., Soukas, A.A., Soukup, S.F., Sousa, D., Sousa, N., Spagnuolo, P.A., Spector, S.A., Srinivas Bharath, M.M., St Clair, D., Stagni, V., Staiano, L., Stalnecker, C.A., Stankov, M.V., Stathopulos, P.B., Stefan, K., Stefan, S.M., Stefanis, L., Steffan, J.S., Steinkasserer, A., Stenmark, H., Sterneckert, J., Stevens, C., Stoka, V., Storch, S., Stork, B., Strappazzon, F., Strohecker, A.M., Stupack, D.G., Su, H., Su, L.Yy, Su, L., Suarez-Fontes, A.M., Subauste, C.S., Subbian, S., Subirada, P.V., Sudhandiran, G., Sue, C.M., Sui, X., Summers, C., Sun, G., Sun, J., Sun, K., Sun, M.X., Sun, Q., Sun, Y., Sun, Z., Sunahara, K.K.S., Sundberg, E., Susztak, K., Sutovsky, P., Suzuki, H., Sweeney, G., Symons, J.D., Sze, S.C.W., Szewczyk, N.J., Tabęcka-Łonczynska, A., Tabolacci, C., Tacke, F., Taegtmeyer, H., Tafani, M., Tagaya, M., Tai, H., Tait, S.W.G., Takahashi, Y., Takats, S., Talwar, P., Tam, C., Tam, S.Y., Tampellini, D., Tamura, A., Tan, C.T., Tan, E.K., Tan, Y.Q., Tanaka, M., Tanaka, M., Tang, D., Tang, J., Tang, T.S., Tanida, I., Tao, Z., Taouis, M., Tatenhorst, L., Tavernarakis, N., Taylor, A., Taylor, G.A., Taylor, J.M., Tchetina, E., Tee, A.R., Tegeder, I., Teis, D., Teixeira, N., Teixeira-Clerc, F., Tekirdag, K.A., Tencomnao, T., Tenreiro, S., Tepikin, A.V., Testillano, P.S., Tettamanti, G., Tharaux, P.L., Thedieck, K., Thekkinghat, A.A., Thellung, S., Thinwa, J.W., Thirumalaikumar, V.P., Thomas, S.M., Thomes, P.G., Thorburn, A., Thukral, L., Thum, T., Thumm, M., Tian, L., Tichy, A., Till, A., Timmerman, V., Titorenko, V.I., Todi, S.V., Todorova, K., Toivonen, J.M., Tomaipitinca, L., Tomar, D., Tomas-Zapico, C., Tomić, S., Tong, B.C.K., Tong, C., Tong, X., Tooze, S.A., Torgersen, M.L., Torii, S., Torres-López, L., Torriglia, A., Towers, C.G., Towns, R., Toyokuni, S., Trajkovic, V., Tramontano, D., Tran, Q.G., Travassos, L.H., Trelford, C.B., Tremel, S., Trougakos, I.P., Tsao, B.P., Tschan, M.P., Tse, H.F., Tse, T.F., Tsugawa, H., Tsvetkov, A.S., Tumbarello, D.A., Tumtas, Y., Tuñón, M.J., Turcotte, S., Turk, B., Turk, V., Turner, B.J., Tuxworth, R.I., Tyler, J.K., Tyutereva, E.V., Uchiyama, Y., Ugun-Klusek, A., Uhlig, H.H., Ułamek-Kozioł, M., Ulasov, I.V., Umekawa, M., Ungermann, C., Unno, R., Urbe, S., Uribe-Carretero, E., Üstün, S., Uversky, V.N., Vaccari, T., Vaccaro, M.I., Vahsen, B.F., Vakifahmetoglu-Norberg, H., Valdor, R., Valente, M.J., Valko, A., Vallee, R.B., Valverde, A.M., Van den Berghe, G., van der Veen, S., Van Kaer, L., van Loosdregt, J., van Wijk, S.J.L., Vandenberghe, W., Vanhorebeek, I., Vannier-Santos, M.A., Vannini, N., Vanrell, M.C., Vantaggiato, C., Varano, G., Varela-Nieto, I., Varga, M., Vasconcelos, M.H., Vats, S., Vavvas, D.G., Vega-Naredo, I., Vega-Rubin-de-Celis, S., Velasco, G., Velázquez, A.P., Vellai, T., Vellenga, E., Velotti, F., Verdier, M., Verginis, P., Vergne, I., Verkade, P., Verma, M., Verstreken, P., Vervliet, T., Vervoorts, J., Vessoni, A.T., Victor, V.M., Vidal, M., Vidoni, C., Vieira, O.V., Vierstra, R.D., Viganó, S., Vihinen, H., Vijayan, V., Vila, M., Vilar, M., Villalba, J.M., Villalobo, A., Villarejo-Zori, B., Villarroya, F., Villarroya, J., Vincent, O., Vindis, C., Viret, C., Viscomi, M.T., Visnjic, D., Vitale, I., Vocadlo, D.J., Voitsekhovskaja, O.V., Volonté, C., Volta, M., Vomero, M., Von Haefen, C., Vooijs, M.A., Voos, W., Vucicevic, L., Wade-Martins, R., Waguri, S., Waite, K.A., Wakatsuki, S., Walker, D.W., Walker, M.J., Walker, S.A., Walter, J., Wandosell, F.G., Wang, B., Wang, C.Y., Wang, C., Wang, C., Wang, C., Wang, C.Y., Wang, D., Wang, F., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H., Wang, H., Wang, H.G., Wang, J., Wang, J., Wang, J., Wang, J., Wang, K., Wang, L., Wang, L., Wang, M.H., Wang, M., Wang, N., Wang, P., Wang, P., Wang, P., Wang, P., Wang, Q.J., Wang, Q., Wang, Q.K., Wang, Q.A., Wang, W.T., Wang, W., Wang, X., Wang, X., Wang, Y., Wang, Y., Wang, Y., Wang, Y.Y., Wang, Y., Wang, Y., Wang, Y., Wang, Y., Wang, Z., Wang, Z., Wang, Z., Warnes, G., Warnsmann, V., Watada, H., Watanabe, E., Watchon, M., Wawrzyńska, A., Weaver, T.E., Wegrzyn, G., Wehman, A.M., Wei, H., Wei, L., Wei, T., Wei, Y., Weiergräber, O.H., Weihl, C.C., Weindl, G., Weiskirchen, R., Wells, A., Wen, R.H., Wen, X., Werner, A., Weykopf, B., Wheatley, S.P., Whitton, J.L., Whitworth, A.J., Wiktorska, K., Wildenberg, M.E., Wileman, T., Wilkinson, S., Willbold, D., Williams, B., Williams, R.S.B., Williams, R.L., Williamson, P.R., Wilson, R.A., Winner, B., Winsor, N.J., Witkin, S.S., Wodrich, H., Woehlbier, U., Wollert, T., Wong, E., Wong, J.H., Wong, R.W., Wong, V.K.W., Wong, W.L., Wu, A.G., Wu, C., Wu, J., Wu, J., Wu, K.K., Wu, M., Wu, S.Y., Wu, S., Wu, S.Y., Wu, S., Wu, W.K.K., Wu, X., Wu, X., Wu, Y.W., Wu, Y., Xavier, R.J., Xia, H., Xia, L., Xia, Z., Xiang, G., Xiang, J., Xiang, M., Xiang, W., Xiao, B., Xiao, G., Xiao, H., Xiao, H.T., Xiao, J., Xiao, L., Xiao, S., Xiao, Y., Xie, B., Xie, C.M., Xie, M., Xie, Y., Xie, Z., Xie, Z., Xilouri, M., Xu, C., Xu, E., Xu, H., Xu, J., Xu, J.R., Xu, L., Xu, W.W., Xu, X., Xue, Y., Yakhine-Diop, S.M.S., Yamaguchi, M., Yamaguchi, O., Yamamoto, A., Yamashina, S., Yan, S., Yan, S.J., Yan, Z., Yanagi, Y., Yang, C., Yang, D.S., Yang, H., Yang, H.T., Yang, H., Yang, J.M., Yang, J., Yang, J., Yang, L., Yang, L., Yang, M., Yang, P.M., Yang, Q., Yang, S., Yang, S., Yang, S.F., Yang, W., Yang, W.Y., Yang, X., Yang, X., Yang, Y., Yang, Y., Yao, H., Yao, S., Yao, X., Yao, Y.G., Yao, Y.M., Yasui, T., Yazdankhah, M., Yen, P.M., Yi, C., Yin, X.M., Yin, Y., Yin, Z., Yin, Z., Ying, M., Ying, Z., Yip, C.K., Yiu, S.P.T., Yoo, Y.H., Yoshida, K., Yoshii, S.R., Yoshimori, T., Yousefi, B., Yu, B., Yu, H., Yu, J., Yu, J., Yu, L., Yu, M.L., Yu, S.W., Yu, V.C., Yu, W.H., Yu, Z., Yu, Z., Yuan, J., Yuan, L.Q., Yuan, S., Yuan, S.S.F., Yuan, Y., Yuan, Z., Yue, J., Yue, Z., Yun, J., Yung, R.L., Zacks, D.N., Zaffagnini, G., Zambelli, V.O., Zanella, I., Zang, Q.S., Zanivan, S., Zappavigna, S., Zaragoza, P., Zarbalis, K.S., Zarebkohan, A., Zarrouk, A., Zeitlin, S.O., Zeng, J., Zeng, J.D., Žerovnik, E., Zhan, L., Zhang, B., Zhang, D.D., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H., Zhang, H.L., Zhang, J., Zhang, J., Zhang, J.P., Zhang, K.Y.B., Zhang, L.W., Zhang, L., Zhang, L., Zhang, L., Zhang, L., Zhang, M., Zhang, P., Zhang, S., Zhang, W., Zhang, X., Zhang, X.W., Zhang, X., Zhang, X., Zhang, X., Zhang, X., Zhang, X.D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y.D., Zhang, Y., Zhang, Y.Y., Zhang, Y., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhang, Z., Zhao, H., Zhao, L., Zhao, S., Zhao, T., Zhao, X.F., Zhao, Y., Zhao, Y., Zhao, Y., Zhao, Y., Zheng, G., Zheng, K., Zheng, L., Zheng, S., Zheng, X.L., Zheng, Y., Zheng, Z.G., Zhivotovsky, B., Zhong, Q., Zhou, A., Zhou, B., Zhou, C., Zhou, G., Zhou, H., Zhou, H., Zhou, H., Zhou, J., Zhou, J., Zhou, J., Zhou, J., Zhou, K., Zhou, R., Zhou, X.J., Zhou, Y., Zhou, Y., Zhou, Y., Zhou, Z.Y., Zhou, Z., Zhu, B., Zhu, C., Zhu, G.Q., Zhu, H., Zhu, H., Zhu, H., Zhu, W.G., Zhu, Y., Zhu, Y., Zhuang, H., Zhuang, X., Zientara-Rytter, K., Zimmermann, C.M., Ziviani, E., Zoladek, T., Zong, W.X., Zorov, D.B., Zorzano, A., Zou, W., Zou, Z., Zou, Z., Zuryn, S., Zwerschke, W., Brand-Saberi, B., Dong, X.C., Kenchappa, C.S., Li, Z., Lin, Y., Oshima, S., Rong, Y., Sluimer, J.C., Stallings, C.L. and Tong, C.K.
Autophagy 17
(1): 1-382.
8 February 2021
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Fleuter, C., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Zincke, F., Smith, J., Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Burock, S., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Oncogene 40
(34): 5286-5301.
26 August 2021
Real-time cell migration monitoring to analyze drug synergism in the scratch assay using the IncuCyte system.
Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Stein, U.S. ORCID: https://orcid.org/0000-0001-7006-282X
Methods in Molecular Biology 2294
: 133-142.
2021
Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Mikuda, N., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Kärgel, E., Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Tufan, A.B. ORCID: https://orcid.org/0000-0002-8734-9736, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Sun, W. ORCID: https://orcid.org/0000-0001-9607-1361, Krahn, I., Schleich, K., von Hoff, L., Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121, Willenbrock, M., Jungmann, S., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
EMBO Journal 40
(6): e104296.
15 March 2021
Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L. ORCID: https://orcid.org/0000-0002-7359-0318, Krupp, F. ORCID: https://orcid.org/0000-0002-0402-8647, Harnett, D. ORCID: https://orcid.org/0000-0002-9190-128X, Turko, P., Ambrozkiewicz, M.C. ORCID: https://orcid.org/0000-0001-5225-5230, Sprink, T. ORCID: https://orcid.org/0000-0002-0760-6828, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Günnigmann, M., Zinnall, U. ORCID: https://orcid.org/0000-0002-0782-7751, Vieira-Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507, Schaub, T. ORCID: https://orcid.org/0000-0003-0790-5040, Münster-Wandowski, A., Bürger, J., Borisova, E., Yamamoto, H., Rasin, M.R., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Mielke, T., Tarabykin, V., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Kramer, G., Vida, I., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Spahn, C.M.T.
Molecular Cell 81
(2): 304-322.
21 January 2021
PET-guided eBEACOPP treatment of advanced-stage Hodgkin lymphoma (HD18): follow-up analysis of an international, open-label, randomised, phase 3 trial.
Kreissl, S., Goergen, H., Buehnen, I., Kobe, C., Moccia, A., Greil, R., Eichenauer, D.A., Zijlstra, J.M., Markova, J., Meissner, J., Feuring-Buske, M., Soekler, M., Beck, H.J., Willenbacher, W., Ludwig, W.D., Pabst, T., Topp, M.S., Hitz, F., Bentz, M., Keller, U.B. ORCID: https://orcid.org/0000-0002-8485-1958, Kühnhardt, D., Ostermann, H., Hertenstein, B., Aulitzky, W., Maschmeyer, G., Vieler, T., Eich, H., Baues, C., Stein, H., Fuchs, M., Diehl, V., Dietlein, M., Engert, A. and Borchmann, P.
Lancet Haematology 8
(6): e398-e409.
June 2021
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities.
Kruse, T., Benz, C. ORCID: https://orcid.org/0000-0002-5166-3598, Garvanska, D.H., Lindqvist, R., Mihalic, F., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Inturi, R. ORCID: https://orcid.org/0000-0003-1344-3962, Sayadi, A., Simonetti, L. ORCID: https://orcid.org/0000-0003-1283-9770, Nilsson, E., Ali, M. ORCID: https://orcid.org/0000-0002-8858-6776, Kliche, J., Moliner Morro, A., Mund, A. ORCID: https://orcid.org/0000-0002-7843-5341, Andersson, E., McInerney, G. ORCID: https://orcid.org/0000-0003-2257-7241, Mann, M., Jemth, P. ORCID: https://orcid.org/0000-0003-1516-7228, Davey, N.E., Överby, A.K. ORCID: https://orcid.org/0000-0001-6553-0940, Nilsson, J. ORCID: https://orcid.org/0000-0003-4100-1125 and Ivarsson, Y. ORCID: https://orcid.org/0000-0002-7081-3846
Nature Communications 12
(1): 6761.
19 November 2021
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.
Krämer, B., Knoll, R. ORCID: https://orcid.org/0000-0001-8320-5885, Bonaguro, L., ToVinh, M. ORCID: https://orcid.org/0000-0002-1625-9741, Raabe, J. ORCID: https://orcid.org/0000-0002-6894-1451, Astaburuaga-García, R., Schulte-Schrepping, J., Kaiser, K.M., Rieke, G.J., Bischoff, J., Monin, M.B., Hoffmeister, C. ORCID: https://orcid.org/0000-0001-6473-4087, Schlabe, S., De Domenico, E., Reusch, N. ORCID: https://orcid.org/0000-0001-5625-0701, Händler, K., Reynolds, G., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Hack, G., Finnemann, C., Nischalke, H.D., Strassburg, C.P., Stephenson, E., Su, Y., Gardner, L., Yuan, D., Chen, D., Goldman, J., Rosenstiel, P., Schmidt, S.V., Latz, E., Hrusovsky, K., Ball, A.J., Johnson, J.M., Koenig, P.A., Schmidt, F.I., Haniffa, M., Heath, J.R., Kümmerer, B.M., Keitel, V., Jensen, B., Stubbemann, P., Kurth, F., Sander, L.E., Sawitzki, B., Aschenbrenner, A.C., Schultze, J.L. and Nattermann, J.
Immunity 54
(11): 2650-2669.
9 November 2021
Sekundäre Immundefekte bei hämatoonkologischen Erkrankungen.
Käbisch, E. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Tagliche Praxis 65
(1): 12-23.
2021
Sekundäre Immundefekte bei hämatoonkologischen Erkrankungen [Secondary immunodeficiency in hematological and oncological diseases].
Käbisch, E. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Internistische Praxis 63
(4): 570-581.
2021
Health workforce response to Covid-19: What pandemic preparedness planning and action at the federal and state levels in Germany? Germany's health workforce responses to Covid-19.
Köppen, J. ORCID: https://orcid.org/0000-0001-7941-641X, Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512 and Maier, C.B. ORCID: https://orcid.org/0000-0002-7734-2258
International Journal of Health Planning and Management 36
(S1): 71-91.
May 2021
Survey of long-term experiences of sperm cryopreservation in oncological and non-oncological patients: usage and reproductive outcomes of a large monocentric cohort.
Lackamp, N., Wilkemeyer, I., Jelas, I., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Stintzing, S. and le Coutre, P.
Frontiers in Oncology 11
: 772809.
5 November 2021
An oscillatory network controlling self-renewal of skeletal muscle stem cells.
Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Zhang, Y. ORCID: https://orcid.org/0000-0001-5841-225X, Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Experimental Cell Research 409
(2): 112933.
15 December 2021
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Muus, C. ORCID: https://orcid.org/0000-0003-2779-0893, Gohil, S.H., Zhao, T., Chiang, Z., Pelka, K., Verboon, J.M., Luo, W., Christian, E., Rosebrock, D., Getz, G. ORCID: https://orcid.org/0000-0002-0936-0753, Boland, G.M., Chen, F. ORCID: https://orcid.org/0000-0003-2308-3649, Buenrostro, J.D. ORCID: https://orcid.org/0000-0001-9958-3987, Hacohen, N. ORCID: https://orcid.org/0000-0002-2349-2656, Wu, C.J. ORCID: https://orcid.org/0000-0002-3348-5054, Aryee, M.J., Regev, A. ORCID: https://orcid.org/0000-0003-3293-3158 and Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X
Nature Biotechnology 39
(4): 451-461.
April 2021
Clinical presentation and management of a dinutuximab beta extravasation in a patient with neuroblastoma.
Launspach, M. ORCID: https://orcid.org/0000-0001-5337-5605, Seif, M., Thole, TM., Jesse, P., Schulz, J., Schulte, J.H., Bischoff, S., Eggert, A. and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Children 8
(2): 91.
29 January 2021
Virus-induced senescence is driver and therapeutic target in COVID-19.
Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Trimpert, J. ORCID: https://orcid.org/0000-0003-1616-0810, Benthani, F. ORCID: https://orcid.org/0000-0002-3283-307X, Mairhofer, M., Richter-Pechanska, P. ORCID: https://orcid.org/0000-0001-6727-6317, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Belenki, D. ORCID: https://orcid.org/0000-0002-9004-9849, Kaltenbrunner, S., Pammer, M., Kausche, L., Firsching, T.C. ORCID: https://orcid.org/0000-0003-1378-4951, Dietert, K., Schotsaert, M., Martínez-Romero, C. ORCID: https://orcid.org/0000-0001-8888-7715, Singh, G. ORCID: https://orcid.org/0000-0003-3260-2631, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Ghanem, R., Salzer, H.J.F., Paar, C., Mülleder, M., Uccellini, M., Michaelis, E.G., Khan, A., Lau, A., Schönlein, M. ORCID: https://orcid.org/0000-0003-3156-3132, Habringer, A., Tomasits, J., Adler, J.M., Kimeswenger, S. ORCID: https://orcid.org/0000-0002-0443-8558, Gruber, A.D. ORCID: https://orcid.org/0000-0002-4502-0393, Hoetzenecker, W., Steinkellner, H., Purfuerst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Motz, R., Di Pierro, F., Lamprecht, B. ORCID: https://orcid.org/0000-0003-3365-3449, Osterrieder, N., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Drosten, C. ORCID: https://orcid.org/0000-0001-7923-0519, García-Sastre, A. ORCID: https://orcid.org/0000-0002-6551-1827, Langer, R., Ralser, M., Eils, R. ORCID: https://orcid.org/0000-0002-0034-4036, Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature 599
(7884): 283-289.
11 November 2021
Technologies for profiling the impact of genomic variants on transcription factor binding.
Leiz, J. ORCID: https://orcid.org/0000-0002-6531-7047, Rutkiewicz, M. ORCID: https://orcid.org/0000-0001-8339-3230, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142
Medizinische Genetik 33
(2): 147-155.
14 August 2021
Investigation of spleen CXCR4 expression by [(68)Ga]Pentixafor PET in a cohort of 145 solid cancer patients.
Lewis, R., Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Kircher, M., Hefter, M., Peuker, C.A. ORCID: https://orcid.org/0000-0002-0957-2166, Werner, R., Ademaj-Kospiri, V., Gäble, A., Weber, W., Wester, H.J., Buck, A., Herhaus, P., Lapa, C. and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
EJNMMI Research 11
(1): 77.
21 August 2021
CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness.
Lewis, R. ORCID: https://orcid.org/0000-0002-2404-6703, Maurer, H.C., Singh, N., Gonzalez-Menendez, I., Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Zhang, L., Isaakidis, K., Scherger, A.K., Schulze, V., Lu, J., Zenz, T. ORCID: https://orcid.org/0000-0001-7890-9845, Steiger, K. ORCID: https://orcid.org/0000-0002-7269-5433, Rad, R., Quintanilla-Martinez, L., Espeli, M., Balabanian, K. ORCID: https://orcid.org/0000-0002-0534-3198, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592
Leukemia 35
: 2895-2905.
October 2021
Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma.
Liang, H.C. ORCID: https://orcid.org/0000-0003-2612-3714, Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Prutsch, N., Zimmerman, M.W. ORCID: https://orcid.org/0000-0003-2489-3889, Gurnhofer, E., Montes-Mojarro, I.A. ORCID: https://orcid.org/0000-0003-0636-7623, Abraham, B.J. ORCID: https://orcid.org/0000-0001-8085-3027, Prokoph, N. ORCID: https://orcid.org/0000-0002-6429-9895, Stoiber, S. ORCID: https://orcid.org/0000-0003-3293-867X, Tangermann, S., Lobello, C., Oppelt, J. ORCID: https://orcid.org/0000-0002-3076-4840, Anagnostopoulos, I., Hielscher, T., Pervez, S., Klapper, W. ORCID: https://orcid.org/0000-0001-7208-4117, Zammarchi, F., Silva, D.A. ORCID: https://orcid.org/0000-0002-3195-9009, Garcia, K.C. ORCID: https://orcid.org/0000-0001-9273-0278, Baker, D. ORCID: https://orcid.org/0000-0001-7896-6217, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Fend, F. ORCID: https://orcid.org/0000-0002-5496-293X, Pospíšilová, Š., Janiková, A., Wallwitz, J., Stoiber, D., Simonitsch-Klupp, I., Cerroni, L., Pileri, S., de Leval, L. ORCID: https://orcid.org/0000-0003-3994-516X, Sibon, D., Fataccioli, V., Gaulard, P., Assaf, C., Knörr, F., Damm-Welk, C., Woessmann, W., Turner, S.D. ORCID: https://orcid.org/0000-0002-8439-4507, Look, A.T. ORCID: https://orcid.org/0000-0001-7851-8617, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Kenner, L. ORCID: https://orcid.org/0000-0003-2184-1338 and Merkel, O. ORCID: https://orcid.org/0000-0001-5089-344X
Nature Communications 12
(1): 5577.
22 September 2021
Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas.
Liebers, N., Duell, J., Fitzgerald, D. ORCID: https://orcid.org/0000-0003-4927-7484, Kerkhoff, A., Noerenberg, D., Kaebisch, E. ORCID: https://orcid.org/0000-0001-7752-4126, Acker, F. ORCID: https://orcid.org/0000-0002-6207-0237, Fuhrmann, S. ORCID: https://orcid.org/0000-0002-7785-2565, Leng, C., Welslau, M., Chemnitz, J., Middeke, J.M., Weber, T. ORCID: https://orcid.org/0000-0002-8724-9348, Holtick, U., Trappe, R., Pfannes, R., Liersch, R., Spoer, C., Fuxius, S., Gebauer, N., Caillé, L., Geer, T., Koenecke, C. ORCID: https://orcid.org/0000-0001-7025-1735, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Claus, R. ORCID: https://orcid.org/0000-0003-2617-8766, Mougiakakos, D., Mayer, S., Huettmann, A. ORCID: https://orcid.org/0000-0003-2230-3873, Pott, C., Trummer, A., Wulf, G., Brunnberg, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Hess, G., Mueller-Tidow, C., Glass, B., Lenz, G., Dreger, P. and Dietrich, S.
Blood Advances 5
(13): 2707-2716.
13 July 2021
Systematic identification of MACC1-driven metabolic networks in colorectal cancer.
Lisec, J. ORCID: https://orcid.org/0000-0003-1220-2286, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Mokrizkij, M., Grötzinger, C. ORCID: https://orcid.org/0000-0001-9872-3087, Jaeger, C., Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Simon, M. ORCID: https://orcid.org/0000-0001-7213-9499, Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Beindorff, N., Brenner, W. ORCID: https://orcid.org/0000-0003-2478-6004 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cancers 13
(5): 978.
26 February 2021
Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily.
Liu, J., Tassinari, M., Souza, D.P., Naskar, S., Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Bohuszewicz, O., Buck, M., Williams, T.A., Baum, B. and Low, H.H.
Cell 184
(14): 3660-3673.
8 July 2021
Microglia sense neuronal activity via GABA in the early postnatal hippocampus.
Logiacco, F. ORCID: https://orcid.org/0000-0003-4696-2240, Xia, P. ORCID: https://orcid.org/0000-0001-5086-1755, Georgiev, S.V. ORCID: https://orcid.org/0000-0001-7978-8811, Franconi, C., Chang, Y.J., Ugursu, B. ORCID: https://orcid.org/0000-0002-2488-4141, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Semtner, M. ORCID: https://orcid.org/0000-0001-9379-9023
Cell Reports 37
(13): 110128.
28 December 2021
Deregulated expression of circular RNAs in acute myeloid leukemia.
Lux, S. ORCID: https://orcid.org/0000-0003-3826-5242, Blätte, T.J. ORCID: https://orcid.org/0000-0002-9859-1261, Gillissen, B., Richter, A., Cocciardi, S., Skambraks, S., Schwarz, K., Schrezenmeier, H., Döhner, H., Döhner, K., Dolnik, A. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood Advances 5
(5): 1490-1503.
9 March 2021
Analysis of correlation and ionization from pair distributions in many-electron systems.
López-Rosa, S. ORCID: https://orcid.org/0000-0002-7667-8462, Angulo, J. C., Martín, A. L. and Antolín, J.
European Physical Journal Plus 136
(7): 763.
22 July 2021
Humoral and cellular immune responses in SARS-CoV-2 mRNA-vaccinated patients with cancer.
Mairhofer, M., Kausche, L., Kaltenbrunner, S., Ghanem, R., Stegemann, M., Klein, K., Pammer, M., Rauscher, I., Salzer, H.J.F., Doppler, S., Habringer, A., Paar, C., Kimeswenger, S., Hoetzenecker, W., Lamprecht, B., Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Cell 39
(9): 1171-1172.
13 September 2021
Locus specific epigenetic modalities of random allelic expression imbalance.
Marion-Poll, L. ORCID: https://orcid.org/0000-0003-4652-9797, Forêt, B., Zielinski, D. ORCID: https://orcid.org/0000-0002-6188-9590, Massip, F. ORCID: https://orcid.org/0000-0001-5855-0935, Attia, M., Carter, A.C., Syx, L., Chang, H.Y. ORCID: https://orcid.org/0000-0002-9459-4393, Gendrel, A.V. ORCID: https://orcid.org/0000-0003-4510-0024 and Heard, E.
Nature Communications 12
(1): 5330.
9 September 2021
GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data.
Markowski, J. ORCID: https://orcid.org/0000-0002-0573-7832, Kempfer, R. ORCID: https://orcid.org/0000-0002-8588-8576, Kukalev, A. ORCID: https://orcid.org/0000-0001-5847-3773, Irastorza-Azcarate, I. ORCID: https://orcid.org/0000-0001-5245-2322, Loof, G. ORCID: https://orcid.org/0000-0003-3967-6115, Kehr, B., Pombo, A. ORCID: https://orcid.org/0000-0002-7493-6288, Rahmann, S. and Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268
Bioinformatics 37
(19): 3128–3135.
1 October 2021
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1.
Marques, C. ORCID: https://orcid.org/0000-0002-8308-5630, Unterkircher, T., Kroon, P., Oldrini, B., Izzo, A., Dramaretska, Y. ORCID: https://orcid.org/0000-0002-9792-0465, Ferrarese, R., Kling, E., Schnell, O., Nelander, S. ORCID: https://orcid.org/0000-0003-1758-1262, Wagner, E.F., Bakiri, L., Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251, Carro, M.S. ORCID: https://orcid.org/0000-0002-8570-7691 and Squatrito, M. ORCID: https://orcid.org/0000-0002-4593-3790
eLife 10
: e64846.
17 August 2021
CoBold: a method for identifying different functional classes of transient RNA structure features that can impact RNA structure formation in vivo.
Martín, A.L., Mounir, M. and Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479
Nucleic Acids Research 49
(4): e19.
26 February 2021
The relevance of the SH2 domain for c-Src functionality in triple-negative breast cancer cells.
Mayoral-Varo, V. ORCID: https://orcid.org/0000-0001-6972-2368, Sánchez-Bailón, M.P. ORCID: https://orcid.org/0000-0001-6929-2273, Calcabrini, A. ORCID: https://orcid.org/0000-0002-9600-1117, García-Hernández, M., Frezza, V., Martín, M.E. ORCID: https://orcid.org/0000-0003-2131-874X, González, V.M. ORCID: https://orcid.org/0000-0001-7538-0552 and Martín-Pérez, J. ORCID: https://orcid.org/0000-0002-2292-0057
Cancers 13
(3): 462.
26 January 2021
Lymphocyte access to lymphoma is impaired by high endothelial venule regression.
Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Zschummel, M. ORCID: https://orcid.org/0000-0002-4778-8742, Crowley, T. ORCID: https://orcid.org/0000-0002-1404-6005, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Grau, M., Ulbricht, C. ORCID: https://orcid.org/0000-0003-2983-6242, Hauser, A., Siffrin, V. ORCID: https://orcid.org/0000-0002-1532-2868, Bajénoff, M., Acton, S.E., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Lenz, G., Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Cell Reports 37
(4): 109878.
26 October 2021
Inferring time series chromatin states for promoter-enhancer pairs based on Hi-C data.
Miko, H. ORCID: https://orcid.org/0000-0001-5911-7586, Qiu, Y., Gaertner, B., Sander, M. ORCID: https://orcid.org/0000-0001-5308-7785 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
BMC Genomics 22
(1): 84.
28 January 2021
Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Mimitou, E.P., Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Chen, K.Y. ORCID: https://orcid.org/0000-0002-4406-2604, Zorzetto-Fernandes, A.L., Hao, Y., Takeshima, Y. ORCID: https://orcid.org/0000-0001-8312-9309, Luo, W. ORCID: https://orcid.org/0000-0002-7041-823X, Huang, T.S. ORCID: https://orcid.org/0000-0001-8902-5439, Yeung, B.Z., Papalexi, E., Thakore, P.I., Kibayashi, T., Wing, J.B. ORCID: https://orcid.org/0000-0002-3462-1003, Hata, M., Satija, R. ORCID: https://orcid.org/0000-0001-9448-8833, Nazor, K.L., Sakaguchi, S., Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X, Regev, A. ORCID: https://orcid.org/0000-0003-3293-3158 and Smibert, P. ORCID: https://orcid.org/0000-0003-0772-1647
Nature Biotechnology 39
(10): 1246-1258.
October 2021
Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy.
Mitra, D., Vega-Rubin-de-Celis, S. ORCID: https://orcid.org/0000-0002-4196-8996, Royla, N., Bernhardt, S., Wilhelm, H., Tarade, N., Poschet, G., Buettner, M., Binenbaum, I., Borgoni, S., Vetter, M., Kantelhardt, E.J., Thomssen, C., Chatziioannou, A., Hell, R., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Müller-Decker, K. and Wiemann, S. ORCID: https://orcid.org/0000-0003-4683-3174
International Journal of Cancer 148
(8): 1993-2009.
15 April 2021
Single-cell genomics to study developmental cell fate decisions in zebrafish.
Moreno-Ayala, R. ORCID: https://orcid.org/0000-0002-8614-1239 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Briefings in Functional Genomics 20
(6): 420–426.
November 2021
Variability of an early developmental cell population underlies stochastic laterality defects.
Moreno-Ayala, R. ORCID: https://orcid.org/0000-0002-8614-1239, Olivares-Chauvet, P., Schäfer, R. and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Cell Reports 34
(2): 108606.
12 January 2021
Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca, P. ORCID: https://orcid.org/0000-0002-9456-4178, Jäntti, N.Z. ORCID: https://orcid.org/0000-0003-1547-0390, Godbole, R., Sommer, C., Jacquemet, G. ORCID: https://orcid.org/0000-0002-9286-920X, Al-Akhrass, H. ORCID: https://orcid.org/0000-0002-9630-3000, Conway, J.R.W. ORCID: https://orcid.org/0000-0003-3787-277X, Kronqvist, P., Kallionpää, R.E. ORCID: https://orcid.org/0000-0003-0146-0060, Oliveira-Ferrer, L., Cervero, P. ORCID: https://orcid.org/0000-0002-9417-7733, Linder, S. ORCID: https://orcid.org/0000-0001-8226-2802, Aepfelbacher, M., Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Rae, J., Parton, R.G. ORCID: https://orcid.org/0000-0002-7494-5248, Disanza, A. ORCID: https://orcid.org/0000-0001-5101-2907, Scita, G. ORCID: https://orcid.org/0000-0001-7984-1889, Mayor, S., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Veltel, S. ORCID: https://orcid.org/0000-0002-4925-3776 and Ivaska, J. ORCID: https://orcid.org/0000-0002-6295-6556
Nature Cell Biology 23
(10): 1073-1084.
October 2021
Assessment of coronary artery disease during hospitalization for cancer treatment.
Mrotzek, S.M., Lena, A., Hadzibegovic, S., Ludwig, R., Al-Rashid, F., Mahabadi, A.A., Mincu, R.I., Michel, L., Johannsen, L., Hinrichs, L., Schuler, M., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Anker, S.D., Landmesser, U., Rassaf, T., Anker, M.S. and Totzeck, M.
Clinical Research in Cardiology 110
(2): 200-210.
February 2021
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Muus, C. ORCID: https://orcid.org/0000-0003-2779-0893, Luecken, M.D. ORCID: https://orcid.org/0000-0001-7464-7921, Eraslan, G., Sikkema, L. ORCID: https://orcid.org/0000-0001-9686-6295, Waghray, A., Heimberg, G., Kobayashi, Y., Vaishnav, E.D. ORCID: https://orcid.org/0000-0003-3720-8051, Subramanian, A. ORCID: https://orcid.org/0000-0002-4134-7612, Smillie, C., Jagadeesh, K.A., Duong, E.T. ORCID: https://orcid.org/0000-0001-7122-4448, Fiskin, E., Triglia, E.T. ORCID: https://orcid.org/0000-0002-6059-0116, Ansari, M. ORCID: https://orcid.org/0000-0002-8819-7965, Cai, P., Lin, B. ORCID: https://orcid.org/0000-0002-8851-3534, Buchanan, J., Chen, S., Shu, J., Haber, A.L., Chung, H., Montoro, D.T., Adams, T., Aliee, H., Allon, S.J., Andrusivova, Z., Angelidis, I., Ashenberg, O., Bassler, K., Bécavin, C., Benhar, I., Bergenstråhle, J., Bergenstråhle, L., Bolt, L., Braun, E., Bui, L.T., Callori, S., Chaffin, M., Chichelnitskiy, E., Chiou, J., Conlon, T.M., Cuoco, M.S., Cuomo, A.S.E., Deprez, M., Duclos, G., Fine, D., Fischer, D.S., Ghazanfar, S., Gillich, A., Giotti, B., Gould, J., Guo, M., Gutierrez, A.J., Habermann, A.C., Harvey, T., He, P., Hou, X., Hu, L., Hu, Y., Jaiswal, A., Ji, L., Jiang, P., Kapellos, T.S., Kuo, C.S., Larsson, L., Leney-Greene, M.A., Lim, K., Litviňuková, M. ORCID: https://orcid.org/0000-0002-6713-3647, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Lukassen, S., Luo, W., Maatz, H., Madissoon, E., Mamanova, L., Manakongtreecheep, K., Leroy, S., Mayr, C.H., Mbano, I.M., McAdams, A.M., Nabhan, A.N., Nyquist, S.K., Penland, L., Poirion, O.B., Poli, S., Qi, C.C., Queen, R., Reichart, D., Rosas, I., Schupp, J.C., Shea, C.V., Shi, X., Sinha, R., Sit, R.V., Slowikowski, K., Slyper, M., Smith, N.P., Sountoulidis, A., Strunz, M., Sullivan, T.B., Sun, D., Talavera-López, C., Tan, P., Tantivit, J., Travaglini, K.J., Tucker, N.R., Vernon, K.A., Wadsworth, M.H., Waldman, J., Wang, X., Xu, K., Yan, W., Zhao, W. and Ziegler, C.G.K.
Nature Medicine 27
(3): 546-559.
2 March 2021
Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Nikolay, R., Hilal, T., Schmidt, S., Qin, B., Schwefel, D. ORCID: https://orcid.org/0000-0002-2945-0908, Vieira-Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507, Mielke, T., Bürger, J., Loerke, J. ORCID: https://orcid.org/0000-0002-3424-8536, Amikura, K., Flügel, T., Ueda, T., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Deuerling, E. and Spahn, C.M.T.
Molecular Cell 81
(6): 1200-1215.
18 March 2021
Genomic landscape and clonal evolution of AML.
Noerenberg, D., Damm, F. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
In:
Acute Myeloid Leukemia.
Hematologic Malignancies
.
Springer, Cham, 103-118.
ISBN 978-3-030-72675-1
2021
Maternal angiotensin increases placental leptin in early gestation via an alternative renin-angiotensin system pathway: suggesting a link to preeclampsia.
Nonn, O. ORCID: https://orcid.org/0000-0001-6385-2866, Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Geisberger, S. ORCID: https://orcid.org/0000-0001-6477-1312, El-Heliebi, A., Kroneis, T. ORCID: https://orcid.org/0000-0002-4761-9340, Forstner, D., Desoye, G., Staff, A.C. ORCID: https://orcid.org/0000-0001-9247-5721, Sugulle, M., Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Pecks, U. ORCID: https://orcid.org/0000-0002-0784-1262, Kollmann, M., Stern, C., Cartwright, J.E., Whitley, G.S., Thilaganathan, B. ORCID: https://orcid.org/0000-0002-5531-4301, Wadsack, C., Huppertz, B. ORCID: https://orcid.org/0000-0003-4814-2158, Herse, F. ORCID: https://orcid.org/0000-0002-9305-8134 and Gauster, M. ORCID: https://orcid.org/0000-0003-0386-6857
Hypertension 77
(5): 1723-1736.
May 2021
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.
Nouailles, G. ORCID: https://orcid.org/0000-0003-1973-3119, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Pennitz, P. ORCID: https://orcid.org/0000-0002-8132-7237, Postmus, D. ORCID: https://orcid.org/0000-0002-9551-0411, Vladimirova, D., Kazmierski, J. ORCID: https://orcid.org/0000-0002-7962-2165, Pott, F. ORCID: https://orcid.org/0000-0003-3700-1691, Dietert, K. ORCID: https://orcid.org/0000-0002-5667-6750, Muelleder, M., Farztdinov, V., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Wienhold, S.M. ORCID: https://orcid.org/0000-0001-5655-4350, Andreotti, S., Hoefler, T. ORCID: https://orcid.org/0000-0001-7486-5582, Sawitzki, B., Drosten, C. ORCID: https://orcid.org/0000-0001-7923-0519, Sander, L.E. ORCID: https://orcid.org/0000-0002-0476-9947, Suttorp, N., Ralser, M., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Gruber, A.D. ORCID: https://orcid.org/0000-0002-4502-0393, Goffinet, C. ORCID: https://orcid.org/0000-0002-3959-004X, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Trimpert, J. ORCID: https://orcid.org/0000-0003-1616-0810 and Witzenrath, M.
Nature Communications 12
(1): 4869.
11 August 2021
High-dose glucocorticoid treatment of near-fatal Bocavirus lung infection results in rapid recovery.
Obenaus, M. ORCID: https://orcid.org/0000-0002-5090-9162, Schildgen, O., Schürmann, D., von Brünneck, A.C., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Gebauer, B., Schilling, J., Schwartz, S. ORCID: https://orcid.org/0000-0001-8833-5793, Weissbrich, B., Schneider, T., Hofmann, J. and Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413
ERJ Open Research 7
(2): 00060-2021.
12 April 2021
Lysine acetylation regulates the interaction between proteins and membranes.
Okada, A.K. ORCID: https://orcid.org/0000-0001-8338-9557, Teranishi, K., Ambroso, M.R., Isas, J.M., Vazquez-Sarandeses, E. ORCID: https://orcid.org/0009-0003-3526-7629, Lee, J.Y. ORCID: https://orcid.org/0000-0001-6616-5594, Melo, A.A., Pandey, P., Merken, D., Berndt, L., Lammers, M., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Chang, K., Haworth, I.S. ORCID: https://orcid.org/0000-0002-3873-0899 and Langen, R.
Nature Communications 12
(1): 6466.
9 November 2021
58/w mit zunehmender psychomotorischer Verlangsamung und Zephalgien [58/f with increasing psychomotor retardation and headache].
Onken, J.S. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Onkologe 27
: 79-84.
September 2021
Effective oncoleaking treatment of pancreatic cancer by claudin-targeted suicide gene therapy with Clostridium perfringens enterotoxin (CPE).
Pahle, J., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Aumann, J., Behrens, D., Daberkow, O., Mokritzkij, M., Piontek, J. ORCID: https://orcid.org/0000-0002-0880-8915, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231
Cancers 13
(17): 4393.
1 September 2021
Longitudinal single-cell dynamics of chromatin accessibility and mitochondrial mutations in chronic lymphocytic leukemia mirror disease history.
Penter, L., Gohil, S.H., Lareau, C. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Parry, E.M., Huang, T., Li, S., Zhang, W., Livitz, D., Leshchiner, I., Parida, L., Getz, G., Rassenti, L.Z., Kipps, T.J., Brown, J.R., Davids, M.S., Neuberg, D.S., Livak, K.J., Sankaran, V.G. and Wu, C.J.
Cancer Discovery 11
(12): 3048-3063.
December 2021
Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes.
Pishesha, N. ORCID: https://orcid.org/0000-0002-8124-1265, Harmand, T., Smeding, L.Y. ORCID: https://orcid.org/0000-0002-3850-1746, Ma, W., Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Janssen, R., Islam, A., Xie, Y.J., Fang, T., McCaul, N. ORCID: https://orcid.org/0000-0002-7888-7815, Pinney, W., Sugito, H.R., Rossotti, M.A., Gonzalez-Sapienza, G. and Ploegh, H.L. ORCID: https://orcid.org/0000-0002-1090-6071
Nature Biomedical Engineering 5
(11): 1389-1401.
November 2021
The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains.
Pluska, L. ORCID: https://orcid.org/0000-0002-8669-6533, Jarosch, E. ORCID: https://orcid.org/0000-0002-5897-3492, Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Kniss, A., Waltho, A. ORCID: https://orcid.org/0009-0000-0059-9357, Bagola, K. ORCID: https://orcid.org/0000-0003-0269-6454, von Delbrück, M., Löhr, F., Schulman, B.A. ORCID: https://orcid.org/0000-0002-3083-1126, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Dötsch, V. and Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202
EMBO Journal 40
(6): e106094.
15 March 2021
RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.
Poetz, F. ORCID: https://orcid.org/0000-0002-5278-8931, Corbo, J., Levdansky, Y. ORCID: https://orcid.org/0000-0003-0708-0771, Spiegelhalter, A. ORCID: https://orcid.org/0000-0001-9526-1067, Lindner, D., Magg, V., Lebedeva, S. ORCID: https://orcid.org/0000-0003-0857-8256, Schweiggert, J. ORCID: https://orcid.org/0000-0002-1272-3762, Schott, J. ORCID: https://orcid.org/0000-0002-2684-1305, Valkov, E. ORCID: https://orcid.org/0000-0002-3721-1739 and Stoecklin, G. ORCID: https://orcid.org/0000-0001-9284-9834
Nature Communications 12
(1): 7175.
9 December 2021
ECG scoring for the evaluation of therapy-naïve cancer patients to predict cardiotoxicity.
Pohl, J. ORCID: https://orcid.org/0000-0001-9142-4869, Mincu, R.I., Mrotzek, S.M., Wakili, R., Mahabadi, A.A. ORCID: https://orcid.org/0000-0003-2336-7991, Potthoff, S.K., Siveke, J.T. ORCID: https://orcid.org/0000-0002-8772-4778, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Landmesser, U., Rassaf, T. ORCID: https://orcid.org/0000-0001-8001-0265, Anker, M.S. and Totzeck, M.
Cancers 13
(6): 1197.
10 March 2021
Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads.
Porubsky, D. ORCID: https://orcid.org/0000-0001-8414-8966, Ebert, P. ORCID: https://orcid.org/0000-0001-7441-532X, Audano, P.A., Vollger, M.R. ORCID: https://orcid.org/0000-0002-8651-1615, Harvey, W.T., Marijon, P. ORCID: https://orcid.org/0000-0002-6694-6873, Ebler, J., Munson, K.M. ORCID: https://orcid.org/0000-0001-8413-6498, Sorensen, M., Sulovari, A. ORCID: https://orcid.org/0000-0003-4354-9020, Haukness, M. ORCID: https://orcid.org/0000-0001-9991-8089, Ghareghani, M., Lansdorp, P.M., Paten, B., Devine, S.E., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Lee, C., Chaisson, M.J.P., Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794, Eichler, E.E. ORCID: https://orcid.org/0000-0002-8246-4014 and Marschall, T. ORCID: https://orcid.org/0000-0002-9376-1030
Nature Biotechnology 39
(3): 302-308.
March 2021
Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression.
Pott, F. ORCID: https://orcid.org/0000-0003-3700-1691, Postmus, D., Brown, R.J.P. ORCID: https://orcid.org/0000-0002-3292-6671, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Neumann, E., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Goffinet, C. ORCID: https://orcid.org/0000-0002-3959-004X
Emerging Microbes & Infections 10
(1): 2151-2168.
16 November 2021
Therapy-induced senescence: opportunities to improve anticancer therapy.
Prasanna, P.G. ORCID: https://orcid.org/0000-0001-8386-926X, Citrin, D.E. ORCID: https://orcid.org/0000-0002-4391-2734, Hildesheim, J., Ahmed, M.M., Venkatachalam, S., Riscuta, G., Xi, D., Zheng, G. ORCID: https://orcid.org/0000-0002-8106-6663, van Deursen, J., Goronzy, J. ORCID: https://orcid.org/0000-0001-7670-1856, Kron, S.J. ORCID: https://orcid.org/0000-0003-1518-2436, Anscher, M.S., Sharpless, N.E. ORCID: https://orcid.org/0000-0001-7078-9455, Campisi, J. ORCID: https://orcid.org/0000-0001-6858-9462, Brown, S.L., Niedernhofer, L.J., O'Loghlen, A., Georgakilas, A.G. ORCID: https://orcid.org/0000-0002-5971-0010, Paris, F. ORCID: https://orcid.org/0000-0002-0176-7348, Gius, D., Gewirtz, D.A. ORCID: https://orcid.org/0000-0003-0437-4934, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Abazeed, M.E. ORCID: https://orcid.org/0000-0002-6614-4440, Kirkland, J.L. ORCID: https://orcid.org/0000-0003-1676-4905, Richmond, A. ORCID: https://orcid.org/0000-0002-9580-900X, Romesser, P.B. ORCID: https://orcid.org/0000-0001-8268-2903, Lowe, S.W., Gil, J. ORCID: https://orcid.org/0000-0002-4303-6260, Mendonca, M.S. ORCID: https://orcid.org/0000-0001-9139-1964, Burma, S., Zhou, D. and Coleman, C.N.
Journal of the National Cancer Institute 113
(10): 1285-1298.
October 2021
cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries.
Qi, M. ORCID: https://orcid.org/0000-0002-8671-3110, Nayar, U. ORCID: https://orcid.org/0000-0002-9024-6084, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Wagle, N. and Rheinbay, E. ORCID: https://orcid.org/0000-0002-5566-6729
BMC Bioinformatics 22
(1): 611.
24 December 2021
YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer.
Quinn, H.M. ORCID: https://orcid.org/0000-0002-1336-5709, Vogel, R., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Lan, L., Messerschmidt, C. ORCID: https://orcid.org/0000-0001-8632-656X, Landshammer, A., Lisek, K. ORCID: https://orcid.org/0000-0002-2406-8830, Château-Joubert, S., Marangoni, E., Koren, E., Fuchs, Y. and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Cancer Research 81
(8): 2116-2127.
April 2021
Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses.
Rajasekaran, S. ORCID: https://orcid.org/0000-0002-1271-6204, Siddiqui, J., Rakijas, J., Nicolay, B., Lin, C., Khan, E., Patel, R., Morris, R., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Boukhali, M., Balasubramanyam, J., Ranjith Kumar, R., Van Rechem, C. ORCID: https://orcid.org/0000-0002-5408-6124, Vogel, C., Elchuri, S.V., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Haas, W., Dyson, N. and Miles, W. ORCID: https://orcid.org/0000-0002-2054-5206
Communications Biology 4
(1): 977.
17 August 2021
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.
Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Sapozhnikova, V., Kowenz-Leutz, E., Zimmermann, K., Nicot, N., Nazarov, P.V., Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Reimer, U., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X
iScience 24
(6): 102686.
25 June 2021
A universal peptide matrix interactomics approach to disclose motif dependent protein binding.
Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Suarez-Artiles, L. ORCID: https://orcid.org/0000-0001-7991-5446, Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Haji, M., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Reimer, U. ORCID: https://orcid.org/0000-0002-3375-6889, Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X
Molecular & Cellular Proteomics 20
: 100135.
13 August 2021
Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia.
Rapaport, F., Neelamraju, Y., Baslan, T., Hassane, D., Gruszczynska, A. ORCID: https://orcid.org/0000-0002-7877-8002, de Massy, M.R. ORCID: https://orcid.org/0000-0002-3048-1680, Farnoud, N., Haddox, S., Lee, T., Medina-Martinez, J., Sheridan, C., Thurmond, A., Becker, M., Bekiranov, S. ORCID: https://orcid.org/0000-0002-3177-4346, Carroll, M., Moses Murdock, H., Valk, P.J.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, D’Andrea, R., Lowe, S.W., Neuberg, D. ORCID: https://orcid.org/0000-0003-2566-3145, Levine, R.L. ORCID: https://orcid.org/0000-0002-7884-1905, Melnick, A. ORCID: https://orcid.org/0000-0002-8074-2287 and Garrett-Bakelman, F.E. ORCID: https://orcid.org/0000-0002-4771-628X
Leukemia 35
(9): 2688-2692.
September 2021
Expanding the phenotype of NUP85 mutations beyond nephrotic syndrome to primary autosomal recessive microcephaly and Seckel syndrome spectrum disorders.
Ravindran, E. ORCID: https://orcid.org/0000-0002-0095-116X, Jühlen, R., Vieira-Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507, Ha, T., Salzberg, Y., Fichtman, B., Luise-Becker, L., Martins, N., Picker-Minh, S., Bessa, P., Arts, P., Jackson, M.R., Taranath, A., Kamien, B., Barnett, C., Li, N., Tarabykin, V., Stoltenburg-Didinger, G., Harel, A., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Dickmanns, A., Fahrenkrog, B., Hu, H., Scott, H. and Kaindl, A.M.
Human Molecular Genetics 30
(22): 2068-2081.
15 November 2021
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma.
Regina, C., Hamed, E. ORCID: https://orcid.org/0000-0002-3595-677X, Andrieux, G., Angenendt, S. ORCID: https://orcid.org/0000-0003-0827-7613, Schneider, M., Ku, M. ORCID: https://orcid.org/0000-0001-5168-4308, Follo, M. ORCID: https://orcid.org/0000-0002-3090-7442, Wachtel, M., Ke, E., Kikuchi, K. ORCID: https://orcid.org/0000-0003-3097-7480, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Schäfer, B.W., Boerries, M. ORCID: https://orcid.org/0000-0002-3670-0602, Wagers, A.J. ORCID: https://orcid.org/0000-0002-0066-0485, Keller, C. ORCID: https://orcid.org/0000-0003-2505-7487 and Hettmer, S. ORCID: https://orcid.org/0000-0003-1709-4448
Life Science Alliance 4
(9): e202001002.
September 2021
Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Schrezenmeier, J.F. ORCID: https://orcid.org/0000-0001-5239-4513, Richter-Pechanska, P. ORCID: https://orcid.org/0000-0001-6727-6317, Dolnik, A., Hick, T.P., Schleich, K., Cai, X., Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Lohneis, P., Masswig, S., Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947, Knittel, G., Flümann, R., Childs, D., Childs, L., Gätjens-Sanchez, A.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rosenwald, A., Reinhardt, H.C. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood 137
(20): 2785-2899.
20 May 2021
Investigating the concept of accessibility for predicting novel RNA-RNA interactions.
Reißer, S. ORCID: https://orcid.org/0000-0003-1224-6967 and Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479
bioRxiv
: 2021.06.03.446902.
3 June 2021
Capecitabine in combination with bendamustine in pretreated women with HER2-negative metastatic breast cancer: results of a phase II trial (AGMT MBC-6).
Rinnerthaler, G., Gampenrieder, S.P. ORCID: https://orcid.org/0000-0002-3966-1071, Petzer, A., Hubalek, M., Petru, E., Sandholzer, M., Andel, J., Balic, M., Melchardt, T., Hauser-Kronberger, C., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Ulmer, H. and Greil, R.
Therapeutic Advances in Medical Oncology 13
: 17588359211042301.
19 October 2021
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine.
Rivera, M., Fichtner, I., Wulf-Goldenberg, A., Sers, C., Merk, J., Patone, G., Alp, K.M. ORCID: https://orcid.org/0000-0001-9919-9838, Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Hoffmann, J. ORCID: https://orcid.org/0000-0003-3880-1658, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231
Neoplasia 23
(1): 21-35.
January 2021
Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma.
Roeschert, I., Poon, E. ORCID: https://orcid.org/0000-0002-0616-2487, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Gatti, M., Giansanti, C. ORCID: https://orcid.org/0000-0003-3229-8385, Jamin, Y. ORCID: https://orcid.org/0000-0003-0350-3757, Ade, C.P. ORCID: https://orcid.org/0000-0001-7226-1179, Gallant, P., Schülein-Völk, C., Beli, P. ORCID: https://orcid.org/0000-0001-9507-9820, Richards, M. ORCID: https://orcid.org/0000-0003-1108-2825, Rosenfeldt, M., Altmeyer, M. ORCID: https://orcid.org/0000-0003-3780-1170, Anderson, J., Eggert, A., Dobbelstein, M., Bayliss, R. ORCID: https://orcid.org/0000-0003-0604-2773, Chesler, L. ORCID: https://orcid.org/0000-0001-7842-2068, Büchel, G. ORCID: https://orcid.org/0000-0001-7070-7341 and Eilers, M. ORCID: https://orcid.org/0000-0002-0376-6533
Nature Cancer 2
(3): 312-326.
March 2021
Charting a DNA repair roadmap for immunoglobulin class switch recombination.
Saha, T., Sundaravinayagam, D. ORCID: https://orcid.org/0000-0003-0717-7530 and Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793
Trends in Biochemical Sciences 46
(3): 184-199.
March 2021
The effect of adjuvant therapies on long-term outcome for primary resected synovial sarcoma in a series of mainly children and adolescents.
Scheer, M. ORCID: https://orcid.org/0000-0002-0665-6268, Vokuhl, C., Bauer, S., Fuchs, J., Loff, S., Timmermann, B., Münter, M., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Koscielniak, E. and Klingebiel, T.
Journal of Cancer Research and Clinical Oncology 147
(12): 3735-3747.
December 2021
Netboost: boosting-supported network analysis improves high-dimensional omics prediction in acute myeloid leukemia and Huntington's disease.
Schlosser, P. ORCID: https://orcid.org/0000-0002-8460-0462, Knaus, J. ORCID: https://orcid.org/0000-0002-7470-3791, Schmutz, M. ORCID: https://orcid.org/0000-0002-7453-7260, Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862, Plass, C. ORCID: https://orcid.org/0000-0003-2554-3952, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Claus, R. ORCID: https://orcid.org/0000-0003-2617-8766, Binder, H. ORCID: https://orcid.org/0000-0002-5666-8662, Lübbert, M. and Schumacher, M. ORCID: https://orcid.org/0000-0002-5037-0099
IEEE/ACM Transactions on Computational Biology and Bioinformatics 18
(6): 2635-2648.
1 November 2021
Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.
Schmalbrock, L.K. ORCID: https://orcid.org/0000-0002-6080-6175, Dolnik, A., Cocciardi, S., Sträng, E., Theis, F., Jahn, N., Panina, E., Blätte, T.J., Herzig, J.K., Skambraks, S., Rücker, F.G., Gaidzik, V.I., Paschka, P., Fiedler, W., Salih, H.R., Wulf, G.G., Schroeder, T., Lübbert, M., Schlenk, R.F., Thol, F., Heuser, M., Larson, R.A., Ganser, A., Stunnenberg, H.G., Minucci, S., Stone, R.M., Bloomfield, C.D., Döhner, H., Döhner, K. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood 137
(22): 3093-3104.
3 June 2021
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Schmelz, K., Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Huska, M. ORCID: https://orcid.org/0000-0002-0912-745X, Cwikla, M.C. ORCID: https://orcid.org/0000-0002-6679-5577, Kruetzfeldt, L.M. ORCID: https://orcid.org/0000-0003-3630-3727, Proba, J., Ambros, P.F., Ambros, I.M., Boral, S., Lodrini, M., Chen, C.Y. ORCID: https://orcid.org/0000-0002-1579-024X, Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, Guergen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997, Kuenkele, A., Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242, Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Hundsdoerfer, P., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201 and Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184
Nature Communications 12
(1): 6804.
23 November 2021
Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis.
Schmidt, O., Nehls, N., Prexler, C., von Heyking, K., Groll, T., Pardon, K., Garcia, H.D. ORCID: https://orcid.org/0000-0002-2578-3350, Hensel, T., Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, A., Steiger, K., Burdach, S. and Richter, G.H.S. ORCID: https://orcid.org/0000-0003-4782-5539
Journal of Experimental & Clinical Cancer Research 40
(1): 322.
15 October 2021
TFE3 activation in a TSC1-altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms.
Schmiester, M., Dolnik, A., Kornak, U., Pfitzner, B., Hummel, M., Treue, D., Hartmann, A., Agaimy, A., Weyerer, V., Lekaj, A., Brakemeier, S., Peters, R., Öllinger, R., Märdian, S., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Striefler, J.K. and Flörcken, A.
Journal of Pathology Clinical Research 7
(1): 3-9.
January 2021
Phenotypic mapping of pathologic cross-talk between glioblastoma and innate immune cells by synthetic genetic tracing.
Schmitt, M.J. ORCID: https://orcid.org/0000-0001-8296-5858, Company, C. ORCID: https://orcid.org/0000-0002-7975-0642, Dramaretska, Y. ORCID: https://orcid.org/0000-0002-9792-0465, Barozzi, I., Göhrig, A., Kertalli, S., Großmann, M., Naumann, H. ORCID: https://orcid.org/0000-0003-3883-0432, Sánchez-Bailón, M.P. ORCID: https://orcid.org/0000-0001-6929-2273, Hulsman, D., Glass, R., Squatrito, M., Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658 and Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251
Cancer Discovery 11
(3): 754-777.
March 2021
A randomized phase 3 trial of autologous vs allogeneic transplantation as part of first-line therapy in poor-risk peripheral T-NHL.
Schmitz, N., Truemper, L.H., Bouabdallah, K., Ziepert, M., Leclerc, M., Cartron, G., Jaccard, A., Reimer, P., Wagner-Drouet, E.M., Wilhelm, M., Sanhes, L., Lamy, T., de Leval, L., Rosenwald, A., Roussel, M., Kroschinsky, F.P., Lindemann, W.W., Dreger, P., Viardot, A., Milpied, N.J., Gisselbrecht, C., Wulf, G.G., Gyan, E., Gaulard, P., Bay, J.O., Glass, B., Poeschel, V., Damaj, G., Sibon, D., Delmer, A.J., Bilger, K., Banos, A., Haenel, M., Dreyling, M., Metzner, B., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Braulke, F., Friedrichs, B., Nickelsen, M., Altmann, B. and Tournilhac, O.
Blood 137
(19): 2646-2656.
13 May 2021
The SUMO pathway in pancreatic cancer: insights and inhibition.
Schneeweis, C., Hassan, Z. ORCID: https://orcid.org/0000-0002-7981-8328, Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Schneider, G. ORCID: https://orcid.org/0000-0003-1840-4508
British Journal of Cancer 124
(3): 531-538.
2 February 2021
Rationale for MYC imaging and targeting in pancreatic cancer.
Schneider, G. ORCID: https://orcid.org/0000-0003-1840-4508, Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Saur, D.
EJNMMI Research 11
(1): 104.
12 October 2021
Automated two-dimensional spatiotemporal analysis of mobile single-molecule FRET probes.
Schrangl, L., Göhring, J., Kellner, F., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Schütz, G.J.
Journal of Visualized Experiments 177
: e63124.
23 November 2021
NEMHESYS - European perspective on the implementation of next-generation sequencing into clinical diagnostics.
Serramito-Gómez, I., Clarke, K.M., Rodríguez-Vicente, A.E., McGimpsey, J.E., Abáigar, M., Díez, C.B., Benito, R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mills, K.I. and Hernández Rivas, J.M.
HemaSphere 5
(3): e541.
March 2021
Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition.
Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658, Kertalli, S., Li, L., Schmitt, M.J. ORCID: https://orcid.org/0000-0001-8296-5858, Dramaretska, Y. ORCID: https://orcid.org/0000-0002-9792-0465, Wierikx, J., Hulsman, D. and Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251
Science Advances 7
(9): eabd7974.
24 February 2021
Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain.
Sheinman, M. ORCID: https://orcid.org/0000-0002-3717-1722, Arkhipova, K., Arndt, P.F. ORCID: https://orcid.org/0000-0003-1762-9836, Dutilh, B.E. ORCID: https://orcid.org/0000-0003-2329-7890, Hermsen, R. ORCID: https://orcid.org/0000-0003-4633-4877 and Massip, F. ORCID: https://orcid.org/0000-0001-5855-0935
eLife 10
: e62719.
9 July 2021
Wie das Immunsystem SARS-CoV-2 den Weg ebnet [How the immune system paves the way for SARS-CoV-2].
Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Hygiene und Medizin 46
(3): 22-23.
2021
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.
Singh, Y. ORCID: https://orcid.org/0000-0001-6919-6273, Trautwein, C., Fendel, R. ORCID: https://orcid.org/0000-0003-4716-0311, Krickeberg, N., Berezhnoy, G., Bissinger, R., Ossowski, S., Salker, M.S., Casadei, N. ORCID: https://orcid.org/0000-0003-2209-0580 and Riess, O.
Heliyon 7
(6): e07147.
June 2021
Characterization of CD8 T cell-mediated mutations in the immunodominant epitope GP33-41 of lymphocytic choriomeningitis virus.
Smyth, M., Khamina, K., Popa, A., Gudipati, V., Agerer, B., Lercher, A., Kosack, L., Endler, L., Baazim, H., Viczenczova, C., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Bergthaler, A.
Frontiers in Immunology 12
: 638485.
14 June 2021
Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy.
Sommariva, E. ORCID: https://orcid.org/0000-0003-2172-4051, Stadiotti, I. ORCID: https://orcid.org/0000-0002-5963-8338, Casella, M., Catto, V. ORCID: https://orcid.org/0000-0002-2589-6283, Dello Russo, A., Carbucicchio, C., Arnaboldi, L. ORCID: https://orcid.org/0000-0002-4017-7631, De Metrio, S., Milano, G., Scopece, A., Casaburo, M., Andreini, D., Mushtaq, S., Conte, E., Chiesa, M. ORCID: https://orcid.org/0000-0001-7427-9954, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Cogliati, E., Paolin, A., König, E. ORCID: https://orcid.org/0000-0002-2079-3525, Meraviglia, V. ORCID: https://orcid.org/0000-0002-9571-0309, De Musso, M., Volani, C., Cattelan, G. ORCID: https://orcid.org/0000-0001-8451-9245, Rauhe, W., Turnu, L. ORCID: https://orcid.org/0000-0001-6536-9798, Porro, B., Pedrazzini, M. ORCID: https://orcid.org/0000-0002-0675-4845, Camera, M., Corsini, A. ORCID: https://orcid.org/0000-0002-9912-9482, Tondo, C., Rossini, A. and Pompilio, G.
EMBO Molecular Medicine 13
(9): e14365.
7 September 2021
Homology-directed repair protects the replicating genome from metabolic assaults.
Somyajit, K., Spies, J., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Kirik, U., Rask, M.B., Lee, J.H., Neelsen, K.J., Mund, A., Jensen, L.J. ORCID: https://orcid.org/0000-0001-7885-715X, Paull, T.T., Mann, M. and Lukas, J.
Developmental Cell 56
(4): 461-477.
22 February 2021
Preface.
Stein, U.S. ORCID: https://orcid.org/0000-0001-7006-282X
Methods in Molecular Biology 2294
: v.
2021
Inhibiting lysine demethylase 1A improves L1CAM-specific CAR T cell therapy by unleashing antigen-independent killing via the FAS-FASL axis.
Sulejmani, O. ORCID: https://orcid.org/0000-0003-1600-317X, Grunewald, L., Andersch, L., Schwiebert, S., Klaus, A., Winkler, A., Astrahantseff, K., Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Anders, K. ORCID: https://orcid.org/0000-0002-0429-200X and Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412
Cancers 13
(21): 5489.
31 October 2021
Neuroblastoma risk assessment and treatment stratification with hybrid capture-based panel sequencing.
Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Kruetzfeldt, L.M. ORCID: https://orcid.org/0000-0003-3630-3727, Heukamp, L.C., Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Theissen, J., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Willing, E.M., Menon, R., Fuchs, S. ORCID: https://orcid.org/0000-0001-9619-4329, Thole, T., Schulte, S., Schmelz, K., Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412, Lang, P., Fuchs, J., Eggert, A., Eckert, C., Fischer, M., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178 and Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201
Journal of Personalized Medicine 11
(8): 691.
August 2021
CD28 co-stimulus achieves superior CAR T cell effector function against solid tumors than 4-1BB co-stimulus.
Textor, A. ORCID: https://orcid.org/0000-0002-9952-4650, Grunewald, L., Anders, K. ORCID: https://orcid.org/0000-0002-0429-200X, Klaus, A., Schwiebert, S., Winkler, A., Stecklum, M., Rolff, J., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Eggert, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Jensen, M.C., Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412
Cancers 13
(5): 1050.
2 March 2021
Patient-specific modeling of diffuse large B-cell lymphoma.
Thobe, K. ORCID: https://orcid.org/0000-0001-8883-0620, Konrath, F. ORCID: https://orcid.org/0000-0002-6843-6252, Chapuy, B. ORCID: https://orcid.org/0000-0002-6485-8773 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
Biomedicines 9
(11): 1655.
10 November 2021
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states.
Triana, S. ORCID: https://orcid.org/0000-0003-0370-7821, Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Jopp-Saile, L. ORCID: https://orcid.org/0000-0002-7032-3003, Raffel, S., Lutz, R., Leonce, D., Antes, M. ORCID: https://orcid.org/0000-0001-6773-6109, Hernández-Malmierca, P. ORCID: https://orcid.org/0000-0003-4529-384X, Ordoñez-Rueda, D. ORCID: https://orcid.org/0000-0002-8387-6707, Ramasz, B., Boch, T., Jann, J.C. ORCID: https://orcid.org/0000-0003-2200-0151, Nowak, D., Hofmann, W.K., Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Hübschmann, D. ORCID: https://orcid.org/0000-0002-6041-7049, Alexandrov, T. ORCID: https://orcid.org/0000-0001-9464-6125, Benes, V. ORCID: https://orcid.org/0000-0002-0352-2547, Trumpp, A., Paulsen, M., Velten, L. ORCID: https://orcid.org/0000-0002-1233-5874 and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Nature Immunology 22
(12): 1577-1589.
December 2021
The discriminative ability of Prostate Health Index to detect prostate cancer is enhanced in combination with miR-222-3p.
Tölle, A., Jung, K., Friedersdorff, F., Maxeiner, A., Lein, M., Fendler, A. ORCID: https://orcid.org/0000-0002-7267-0981 and Stephan, C.
Cancer Biomarkers 30
(4): 381-393.
9 April 2021
Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.
Uhlitz, F. ORCID: https://orcid.org/0000-0001-9176-4660, Bischoff, P. ORCID: https://orcid.org/0000-0002-4442-7116, Peidli, S. ORCID: https://orcid.org/0000-0002-4257-8690, Sieber, A., Trinks, A. ORCID: https://orcid.org/0000-0001-9983-1506, Lüthen, M. ORCID: https://orcid.org/0000-0001-5557-6419, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Ruchiy, Y., Sell, T. ORCID: https://orcid.org/0000-0002-5138-3967, Mamlouk, S. ORCID: https://orcid.org/0000-0001-7285-1320, Arsie, R. ORCID: https://orcid.org/0000-0002-7869-7624, Wei, T.T. ORCID: https://orcid.org/0000-0001-5719-721X, Klotz-Noack, K., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Sawitzki, B., Kamphues, C., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Sers, C., Horst, D. ORCID: https://orcid.org/0000-0003-4755-5743, Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447 and Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999
EMBO Molecular Medicine 13
(10): e14123.
7 October 2021
Insulin mRNA is stored in RNA granules in resting beta cells.
Vasiljević, J. ORCID: https://orcid.org/0000-0001-5950-2011, Vasiljević, D., Ganß, K., Sönmez, A., Wegbrod, C., Quezada, E., Münster, C., Schöniger, E., Friedland, D., Kipke, N., Distler, M., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Solimena, M. ORCID: https://orcid.org/0000-0002-3653-8107
bioRxiv
: 2021.05.07.443159v2.
29 June 2021
Three-dimensional single molecule localization microscopy reveals the topography of the immunological synapse at isotropic precision below 15 nm.
Velas, L., Brameshuber, M. ORCID: https://orcid.org/0000-0001-8672-2255, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Kurz, E., Dustin, M.L. ORCID: https://orcid.org/0000-0003-4983-6389, Zelger, P., Jesacher, A. and Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089
Nano Letters 21
(21): 9247-9255.
10 November 2021
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Velten, L. ORCID: https://orcid.org/0000-0002-1233-5874, Story, B.A. ORCID: https://orcid.org/0000-0001-7212-7842, Hernández-Malmierca, P. ORCID: https://orcid.org/0000-0003-4529-384X, Raffel, S., Leonce, D.R., Milbank, J., Paulsen, M., Demir, A. ORCID: https://orcid.org/0000-0001-7327-7682, Szu-Tu, C., Frömel, R., Lutz, C., Nowak, D. ORCID: https://orcid.org/0000-0001-7130-7921, Jann, J.C. ORCID: https://orcid.org/0000-0003-2200-0151, Pabst, C., Boch, T., Hofmann, W.K., Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051 and Steinmetz, L.M.
Nature Communications 12
(1): 1366.
1 March 2021
A barcoded flow cytometric assay to explore the antibody responses against SARS-CoV-2 spike and its variants.
Vesper, N., Ortiz, Y., Bartels-Burgahn, F., Yang, J., de la Rosa, K. ORCID: https://orcid.org/0000-0003-4809-3157, Tenbusch, M., Schulz, S., Finzel, S., Jäck, H.M., Eibel, H., Voll, R.E. and Reth, M.
Frontiers in Immunology 12
: 730766.
September 2021
Opportunities and challenges in global quantification of RNA-protein interaction via UV cross-linking.
Vieira-Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Frontiers in Molecular Biosciences 8
: 669939.
13 May 2021
Cannabidiol converts NF(κ)B into a tumor suppressor in glioblastoma with defined antioxidative properties.
Volmar, M.N.M., Cheng, J., Alenezi, H., Richter, S., Haug, A., Hassan, Z., Goldberg, M., Li, Y., Hou, M., Herold-Mende, C., Maire, C.L., Lamszus, K., Flüh, C., Held-Feindt, J., Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251, Topping, G.J., Schilling, F., Saur, D., Schneider, G., Synowitz, M., Schick, J.A., Kälin, R.E. and Glass, R.
Neuro-Oncology 23
(11): 1898-1910.
November 2021
Early response to first-line anti-PD-1 treatment in Hodgkin lymphoma: a PET-based analysis from the prospective, randomized phase II NIVAHL trial.
Voltin, C.A., Mettler, J., van Heek, L., Goergen, H., Müller, H., Baues, C., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Meissner, J., Trautmann-Grill, K., Kerkhoff, A., Fuchs, M., Sasse, S., von Tresckow, B., Dietlein, M., Borchmann, P., Engert, A., Kobe, C. and Bröckelmann, P.J.
Clinical Cancer Research 27
(2): 402-407.
January 2021
Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript.
Wahlster, L. ORCID: https://orcid.org/0000-0001-8409-7580, Verboon, J.M. ORCID: https://orcid.org/0000-0002-4454-6043, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Black, S.C. ORCID: https://orcid.org/0000-0002-0209-6283, Luo, W. ORCID: https://orcid.org/0000-0002-7041-823X, Garg, K. ORCID: https://orcid.org/0000-0003-0124-7710, Voit, R.A. ORCID: https://orcid.org/0000-0002-6790-8641, Collins, R.L. ORCID: https://orcid.org/0000-0003-1268-9995, Garimella, K. ORCID: https://orcid.org/0000-0002-6212-5736, Costello, M. ORCID: https://orcid.org/0000-0002-0281-3035, Chao, K.R. ORCID: https://orcid.org/0000-0003-2897-2410, Goodrich, J.K. ORCID: https://orcid.org/0000-0003-0480-1924, DiTroia, S.P. ORCID: https://orcid.org/0000-0002-6847-6780, O’Donnell-Luria, A. ORCID: https://orcid.org/0000-0001-6418-9592, Talkowski, M.E. ORCID: https://orcid.org/0000-0003-2889-0992, Michelson, A.D. ORCID: https://orcid.org/0000-0002-1746-4819, Cantor, A.B. ORCID: https://orcid.org/0000-0002-5136-028X and Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X
Journal of Experimental Medicine 218
(6): e20210444.
7 June 2021
Herpesviral induction of germline transcription factor DUX4 is critical for viral gene expression.
Walter, S., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Drayman, N., Tay, S., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Ensser, A. and Full, F.
[Dataset]
21 May 2021
KDD Health Day/DSHealth 2021: Joint KDD 2021 Health Day and 2021 KDD Workshop on Applied Data Science for Healthcare: state of XAI and trustworthiness in health.
Wang, F., Chakraborty, P., Xu, T., Hsueh, P.Y.S., Sun, X., Stiglic, G., Crane, G., Bian, J., Haghverdi, L. ORCID: https://orcid.org/0000-0001-9280-9170, Yao, L. and Buettner, F.
In: KDD '21: The 27th ACM SIGKDD Conference on Knowledge Discovery and Data Mining, 14-18 Aug 2021, Virtual Event Singapore.
14 August 2021
TLR7 signaling drives the development of Sjögren's syndrome.
Wang, Y., Roussel-Queval, A., Chasson, L., Hanna Kazazian, N., Marcadet, L., Nezos, A., Sieweke, M.H. ORCID: https://orcid.org/0000-0002-3228-9537, Mavragani, C. and Alexopoulou, L.
Frontiers in Immunology 12
: 676010.
24 May 2021
Swarm Learning for decentralized and confidential clinical machine learning.
Warnat-Herresthal, S., Schultze, H., Shastry, K.L., Manamohan, S., Mukherjee, S., Garg, V., Sarveswara, R., Händler, K., Pickkers, P., Aziz, N.A., Ktena, S., Tran, F., Bitzer, M., Ossowski, S., Casadei, N., Herr, C., Petersheim, D., Behrends, U., Kern, F., Fehlmann, T., Schommers, P., Lehmann, C., Augustin, M., Rybniker, J., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Mishra, N., Bernardes, J.P., Krämer, B., Bonaguro, L., Schulte-Schrepping, J., De Domenico, E., Siever, C., Kraut, M., Desai, M., Monnet, B., Saridaki, M., Siegel, C.M., Drews, A., Nuesch-Germano, M., Theis, H., Heyckendorf, J., Schreiber, S., Kim-Hellmuth, S., Nattermann, J., Skowasch, D., Kurth, I., Keller, A., Bals, R., Nürnberg, P., Rieß, O., Rosenstiel, P., Netea, M.G., Theis, F., Mukherjee, S., Backes, M., Aschenbrenner, A.C., Ulas, T., Breteler, M.M.B., Giamarellos-Bourboulis, E.J., Kox, M., Becker, M., Cheran, S., Woodacre, M.S., Goh, E.L. and Schultze, J.L.
Nature 594
(7862): 265-270.
10 June 2021
Extend, don’t rebuild: Phrasing conditional graph modification as autoregressive sequence labelling.
Weber, L. ORCID: https://orcid.org/0000-0002-2499-472X, Münchmeyer, J., Garda, S. and Leser, U.
In: 2021 Conference on Empirical Methods in Natural Language Processing, EMNLP 2021, 7-11 Nov 2021, Punta Cana, Dominican Republic.
November 2021
HunFlair: an easy-to-use tool for state-of-the-art biomedical named entity recognition.
Weber, L. ORCID: https://orcid.org/0000-0002-2499-472X, Sänger, M., Münchmeyer, J., Habibi, M., Leser, U. and Akbik, A.
Bioinformatics 37
(17): 2792–2794.
1 September 2021
Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex.
Weigt, M., Gao, Q. ORCID: https://orcid.org/0000-0002-9930-8499, Ban, H., He, H., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627 and Li, F. ORCID: https://orcid.org/0000-0002-1206-9684
Epigenetics & Chromatin 14
(1): 8.
19 January 2021
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.
Wendisch, D., Dietrich, O., Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, von Stillfried, S., Ibarra, I.L., Mittermaier, M., Mache, C., Chua, R.L., Knoll, R., Timm, S., Brumhard, S., Krammer, T., Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Hiller, A.L., Pascual-Reguant, A., Mothes, R., Bülow, R.D., Schulze, J., Leipold, A.M., Djudjaj, S., Erhard, F., Geffers, R., Pott, F., Kazmierski, J., Radke, J., Pergantis, P., Baßler, K., Conrad, C., Aschenbrenner, A.C., Sawitzki, B., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Horst, D., Hippenstiel, S., Hocke, A., Heppner, F.L., Uhrig, A., Garcia, C., Machleidt, F., Herold, S., Elezkurtaj, S., Thibeault, C., Witzenrath, M., Cochain, C., Suttorp, N., Drosten, C., Goffinet, C., Kurth, F., Schultze, J.L., Radbruch, H., Ochs, M., Eils, R., Müller-Redetzky, H., Hauser, A.E., Luecken, M.D., Theis, F.J., Conrad, C., Wolff, T., Boor, P., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Saliba, A.E. and Sander, L.E.
Cell 184
(26): 6243-6261.
22 December 2021
Myeloid transformation by MLL-ENL depends strictly on C/EBP.
Wesolowski, R. ORCID: https://orcid.org/0009-0002-7228-1051, Kowenz-Leutz, E., Zimmermann, K., Dörr, D. ORCID: https://orcid.org/0000-0001-8575-7560, Hofstätter, M. ORCID: https://orcid.org/0000-0002-6198-2859, Slany, R.K., Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427 and Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X
Life Science Alliance 4
(1): e202000709.
January 2021
The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells.
Wilhelmi, Ilka, Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Gimber, N. ORCID: https://orcid.org/0000-0001-9456-3063, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Arumughan, A., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Laeger, T. ORCID: https://orcid.org/0000-0002-2763-0497, Schmoranzer, J., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Schümann, A. ORCID: https://orcid.org/0000-0002-4113-4377
Molecular Metabolism 45
: 101151.
March 2021
In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo.
Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Beier, C., Immisch, L. ORCID: https://orcid.org/0000-0001-5072-8583, Papafotiou, G., Scheuplein-Schlosser, V., Goede, A., Holzhütter, H.G., Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Kloetzel, P.M.
eLife 10
: e62019.
20 April 2021
Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Willnow, D. ORCID: https://orcid.org/0000-0001-6220-3901, Benary, U. ORCID: https://orcid.org/0000-0001-7801-8639, Margineanu, A. ORCID: https://orcid.org/0000-0002-6634-9729, Vignola, M.L. ORCID: https://orcid.org/0000-0001-7121-7715, Konrath, F. ORCID: https://orcid.org/0000-0002-6843-6252, Pongrac, I.M., Karimaddini, Z., Vigilante, A., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868 and Spagnoli, F.M. ORCID: https://orcid.org/0000-0001-7094-8188
Nature 597
(7874): 87-91.
2 September 2021
The mTOR inhibitor temsirolimus added to rituximab combined with dexamethasone, cytarabine, and cisplatinum (R-DHAP) for the treatment of patients with relapsed or refractory DLBCL - results from the phase-II STORM trial.
Witzens-Harig, M., Viardot, A., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Wosniok, J., Deuster, O., Klemmer, J., Geueke, A.M., Meißner, J., Ho, A.D., Atta, J., Marks, R., La Rosée, P., Buske, C., Dreyling, M.H. and Hess, G.
HemaSphere 5
(10): e636.
October 2021
Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.
Worpenberg, L., Paolantoni, C., Longhi, S., Mulorz, M.M., Lence, T. ORCID: https://orcid.org/0000-0001-9377-546X, Wessels, H.H. ORCID: https://orcid.org/0000-0001-5551-404X, Dassi, E., Aiello, G. ORCID: https://orcid.org/0000-0001-8723-2127, Sutandy, F.X.R., Scheibe, M., Edupuganti, R.R., Busch, A., Möckel, M.M., Vermeulen, M. ORCID: https://orcid.org/0000-0003-0836-6894, Butter, F. ORCID: https://orcid.org/0000-0002-7197-7279, König, J., Notarangelo, M., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Dieterich, C. ORCID: https://orcid.org/0000-0001-9468-6311, Quattrone, A. ORCID: https://orcid.org/0000-0003-3333-7630, Soldano, A. ORCID: https://orcid.org/0000-0002-3120-9929 and Roignant, J.Y. ORCID: https://orcid.org/0000-0003-1395-2150
EMBO Journal 40
(4): e104975.
15 February 2021
Bioprinted cancer model of neuroblastoma in a renal microenvironment as an efficiently applicable drug testing platform.
Wu, D. ORCID: https://orcid.org/0000-0001-5446-7376, Berg, J., Arlt, B. ORCID: https://orcid.org/0000-0002-6665-4037, Röhrs, V., Al-Zeer, M.A., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893 and Kurreck, J. ORCID: https://orcid.org/0000-0002-1469-0052
International Journal of Molecular Sciences 23
(1): 122.
23 December 2021
Wnt signalling pathway in bladder cancer.
Wu, G. ORCID: https://orcid.org/0000-0002-5654-8046, Weng, W., Xia, P. ORCID: https://orcid.org/0000-0001-5086-1755, Yan, S., Zhong, C., Xie, L., Xie, Y. and Fan, G.
Cellular Signalling 79
: 109886.
March 2021
Identification of unique long non-coding RNAs as putative biomarkers for chromophobe renal cell carcinoma.
Wu, G. ORCID: https://orcid.org/0000-0001-9711-452X, Xia, P. ORCID: https://orcid.org/0000-0001-5086-1755, Yan, S., Chen, D., Xie, L. and Fan, G.
Personalized Medicine 18
(1): 9-19.
January 2021
Alemtuzumab plus CHOP versus CHOP in elderly patients with peripheral T-cell lymphoma: the DSHNHL2006-1B/ACT-2 trial.
Wulf, G.G., Altmann, B., Ziepert, M., D'Amore, F., Held, G., Greil, R., Tournilhac, O., Relander, T., Viardot, A., Wilhelm, M., Wilhelm, C., Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470, Zijlstra, J.M., Van Den Neste, E., Lugtenburg, P.J., Doorduijn, J.K., van Gelder, M., van Imhoff, G.W., Zettl, F., Braulke, F., Nickelsen, M., Glass, B., Rosenwald, A., Gaulard, P., Loeffler, M., Pfreundschuh, M. ORCID: https://orcid.org/0000-0001-6982-8218, Schmitz, N. and Trümper, L.
Leukemia 35
(1): 143-155.
January 2021
Patient-derived xenografts from solid tumors (PDX) for models of metastasis.
Wulf-Goldenberg, A., Hoffmann, J. ORCID: https://orcid.org/0000-0003-3880-1658, Becker, M., Brzezicha, B. and Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231
Methods in Molecular Biology 2294
: 43-58.
2021
Aberrant expression of and cell death induction by engagement of the MHC-II chaperone CD74 in anaplastic large cell lymphoma (ALCL).
Wurster, K.D., Costanza, M. ORCID: https://orcid.org/0000-0002-8959-1083, Kreher, S., Glaser, S., Lamprecht, B., Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Anagnostopoulos, I., Hummel, M., Jöhrens, K., Stein, H., Molina, A., Diepstra, A. ORCID: https://orcid.org/0000-0001-9239-1050, Gillissen, B., Köchert, K. ORCID: https://orcid.org/0000-0002-5548-2022, Siebert, R., Merkel, O., Kenner, L. ORCID: https://orcid.org/0000-0003-2184-1338, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044 and Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413
Cancers 13
(19): 5012.
1 October 2021
Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.
Wust, P., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Ghadjar, P.
International Journal of Hyperthermia 38
(1): 715-731.
28 April 2021
Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Mösbauer, K., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Diag, A., Gottula, L.T., Arsiè, R. ORCID: https://orcid.org/0000-0002-7869-7624, Klironomos, F., Koppstein, D. ORCID: https://orcid.org/0000-0002-8618-7237, Hönzke, K., Ayoub, S. ORCID: https://orcid.org/0000-0001-5043-8922, Buccitelli, C. ORCID: https://orcid.org/0000-0002-2637-2131, Hoffmann, K., Richter, A., Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, Del Giudice, S. ORCID: https://orcid.org/0000-0003-0194-3767, Papies, J., Praktiknjo, S. ORCID: https://orcid.org/0000-0002-0186-5271, Meyer, T.F., Müller, M.A., Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Hocke, A., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Drosten, C. and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
iScience 24
(3): 102151.
19 March 2021
CRNKL1 is a highly selective regulator of intron-retaining HIV-1 and cellular mRNAs.
Xiao, H., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Milek, M. ORCID: https://orcid.org/0000-0002-0803-8439, Grewe, B., Kirchner, P., Ekici, A., Silva, A.B.O.V., Jungnickl, D., Full, F., Thomas, M. ORCID: https://orcid.org/0000-0003-4820-2712, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Ensser, A. ORCID: https://orcid.org/0000-0001-8873-3863 and Überla, K. ORCID: https://orcid.org/0000-0001-7822-3835
mBio 12
(1): e02525-20.
19 January 2021
ME2 promotes proneural–mesenchymal transition and lipogenesis in glioblastoma.
Yang, M., Chen, X., Zhang, J., Xiong, E. ORCID: https://orcid.org/0000-0001-5124-6922, Wang, Q., Fang, W., Li, L., Fei, F. and Gong, A.
Frontiers in Oncology 11
: 715593.
23 July 2021
Depletion of aneuploid cells in human embryos and gastruloids.
Yang, M., Rito, T., Metzger, J. ORCID: https://orcid.org/0000-0001-6813-4425, Naftaly, J., Soman, R., Hu, J., Albertini, D.F. ORCID: https://orcid.org/0000-0001-7182-833X, Barad, D.H., Brivanlou, A.H. ORCID: https://orcid.org/0000-0002-1761-280X and Gleicher, N. ORCID: https://orcid.org/0000-0002-0202-4167
Nature Cell Biology 23
(4): 314-321.
April 2021
Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging.
Young, K., Eudy, E., Bell, R., Loberg, M.A., Stearns, T., Sharma, D., Velten, L., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Filippi, M.D. and Trowbridge, J.J.
Cell Stem Cell 28
(8): 1473-1482.
5 August 2021
Asymmetric opening of the homopentameric 5-HT(3A) serotonin receptor in lipid bilayers.
Zhang, Y. ORCID: https://orcid.org/0000-0002-6478-476X, Dijkman, P.M. ORCID: https://orcid.org/0000-0001-6799-2399, Zou, R., Zandl-Lang, M., Sanchez, R.M., Eckhardt-Strelau, L., Köfeler, H. ORCID: https://orcid.org/0000-0002-2725-9616, Vogel, H., Yuan, S. and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
Nature Communications 12
(1): 1074.
16 February 2021
Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells.
Zhang, Y. ORCID: https://orcid.org/0000-0001-5841-225X, Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Shimojo, H., Mourikis, P., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Kageyama, R. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Nature Communications 12
(1): 1318.
26 February 2021
A simple pressure-assisted method for MicroED specimen preparation.
Zhao, J. ORCID: https://orcid.org/0000-0001-8444-6883, Xu, H. ORCID: https://orcid.org/0000-0002-8271-3906, Lebrette, H., Carroni, M. ORCID: https://orcid.org/0000-0002-7697-6427, Taberman, H. ORCID: https://orcid.org/0000-0001-7595-4608, Högbom, M. and Zou, X. ORCID: https://orcid.org/0000-0001-6748-6656
Nature Communications 12
(1): 5036.
19 August 2021
Generation of human iPSC-derived neural progenitor cells (NPCs) as drug discovery model for neurological and mitochondrial disorders.
Zink, A. ORCID: https://orcid.org/0000-0002-8489-6339, Lisowski, P. ORCID: https://orcid.org/0000-0002-3634-1072 and Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952
Bio-protocol 11
(5): e3939.
5 March 2021
SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency.
de Melo Costa, V.R., Pfeuffer, J., Louloupi, A. ORCID: https://orcid.org/0000-0003-3729-9002, Ørom, U.A.V. and Piro, R.M. ORCID: https://orcid.org/0000-0002-3066-7397
BMC Bioinformatics 22
(1): 368.
15 July 2021
An introduction to advanced targeted acquisition methods.
van Bentum, M. and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Molecular & Cellular Proteomics 20
: 100165.
18 October 2021
High-affinity T-cell receptor specific for MyD88 L265P mutation for adoptive T-cell therapy of B-cell malignancies.
Çınar, Ö. ORCID: https://orcid.org/0000-0001-5297-127X, Brzezicha, B., Grunert, C. ORCID: https://orcid.org/0000-0001-8376-8629, Kloetzel, P.M., Beier, C., Peuker, C.A. ORCID: https://orcid.org/0000-0002-0957-2166, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470 and Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947
Journal for ImmunoTherapy of Cancer 9
(7): e002410.
30 July 2021
The role of microbiota in primary sclerosing cholangitis and related biliary malignancies.
Özdirik, B. ORCID: https://orcid.org/0000-0002-8885-737X, Müller, T. ORCID: https://orcid.org/0000-0003-3426-5421, Wree, A., Tacke, F. ORCID: https://orcid.org/0000-0001-6206-0226 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
International Journal of Molecular Sciences 22
(13): 6975.
1 July 2021
2020
Cellular drivers of injury response and regeneration in the adult zebrafish heart (zebrafish).
[Dataset]
5 October 2020
Pan-cancer analysis of whole genomes.
Nature 578
(7793): 82-93.
6 February 2020
Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML).
Agrawal, M., Schwarz, P., Giaimo, B.D., Bedzhov, I., Corbacioglu, A., Weber, D., Gaidzik, V.I., Jahn, N., Rücker, F.G., Schroeder, T., Kindler, T., Wattad, M., Götze, K., Lübbert, M., Salwender, H., Ringhoffer, M., Lange, E., Koller, E., Thol, F., Heuser, M., Ganser, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Paschka, P., Döhner, H., Geiger, H., Borggrefe, T., Döhner, K. and Oswald, F.
Leukemia 34
(2): 630-634.
February 2020
Single-cell and spatial transcriptomics approaches of the bone marrow microenvironment.
Al-Sabah, J., Baccin, C. ORCID: https://orcid.org/0000-0003-1251-6947 and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Current Opinion in Oncology 32
(2): 146-153.
1 March 2020
Tumor-derived extracellular vesicles impair CD171-specific CD4(+) CAR T cell efficacy.
Ali, S., Toews, K., Schwiebert, S., Klaus, A., Winkler, A., Grunewald, L., Oevermann, L., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Tüns, A., Jensen, M.C., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, A., Schulte, J.H., Schwich, E., Rebmann, V., Schramm, A. and Künkele, A.
Frontiers in Immunology 11
: 531.
31 March 2020
Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L., Peeva, P. ORCID: https://orcid.org/0000-0001-9937-2397, Ramos-Prats, A., Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Winter, Y. and Rivalan, M. ORCID: https://orcid.org/0000-0002-1642-7522
Behavioural Brain Research 377
: 112188.
13 January 2020
Order and disorder: abnormal 3D chromatin organization in human disease.
Anania, C. ORCID: https://orcid.org/0000-0003-1549-4157 and Lupianez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X
Briefings in Functional Genomics 19
(2): 128-138.
March 2020
Early life stress regulates cardiac development through an IL4-glucocorticoid signaling balance.
Apaydin, D.C., Jaramillo, P.A.M., Corradi, L. ORCID: https://orcid.org/0000-0001-8837-6544, Cosco, F., Rathjen, F.G. ORCID: https://orcid.org/0000-0001-5351-613X, Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141, Filosa, A. ORCID: https://orcid.org/0000-0003-2599-6951 and Sawamiphak, S. ORCID: https://orcid.org/0000-0003-2298-3565
Cell Reports 33
(7): 108404.
17 November 2020
Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773
Clinical and Translational Oncology 22
(12): 2357-2363.
December 2020
Loss of m(1)acp(3)Ψ ribosomal RNA modification is a major feature of cancer.
Babaian, A., Rothe, K. ORCID: https://orcid.org/0000-0001-7190-5024, Girodat, D., Minia, I. ORCID: https://orcid.org/0000-0003-1012-3373, Djondovic, S., Milek, M. ORCID: https://orcid.org/0000-0002-0803-8439, Spencer Miko, S.E., Wieden, H.J., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Morin, G.B. and Mager, D.L.
Cell Reports 31
(5): 107611.
5 May 2020
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.
Baccin, C. ORCID: https://orcid.org/0000-0003-1251-6947, Al-Sabah, J. ORCID: https://orcid.org/0000-0003-2635-0423, Velten, L. ORCID: https://orcid.org/0000-0002-1233-5874, Helbling, P.M. ORCID: https://orcid.org/0000-0001-6488-2805, Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Hernández-Malmierca, P. ORCID: https://orcid.org/0000-0003-4529-384X, Nombela-Arrieta, C. ORCID: https://orcid.org/0000-0003-0415-259X, Steinmetz, L.M. ORCID: https://orcid.org/0000-0002-3962-2865, Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466 and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Nature Cell Biology 22
(1): 38-48.
January 2020
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey, M.H. ORCID: https://orcid.org/0000-0003-4526-9727, Meyerson, W.U., Dursi, L.J. ORCID: https://orcid.org/0000-0002-4697-798X, Wang, L.B. ORCID: https://orcid.org/0000-0001-6977-9348, Dong, G. ORCID: https://orcid.org/0000-0002-4747-6036, Liang, W.W., Weerasinghe, A. ORCID: https://orcid.org/0000-0003-3568-5823, Li, S. ORCID: https://orcid.org/0000-0002-5440-2780, Li, Y., Kelso, S., Saksena, G. ORCID: https://orcid.org/0000-0001-6630-7935, Ellrott, K. ORCID: https://orcid.org/0000-0002-6573-5900, Wendl, M.C., Wheeler, D.A. ORCID: https://orcid.org/0000-0002-9056-6299, Getz, G. ORCID: https://orcid.org/0000-0002-0936-0753, Simpson, J.T., Gerstein, M.B. ORCID: https://orcid.org/0000-0002-9746-3719 and Ding, Li
Nature Communications 11
(1): 4748.
21 September 2020
Co-activation of NF-κB and MYC renders cancer cells addicted to IL6 for survival and phenotypic stability.
Barbosa, R.R., Xu, A.Q., D'Andrea, D., Copley, F., Patel, H., Chakravarty, P., Clear, A., Calaminici, M., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Zhang, B., Schmidt-Supprian, M., Wang, J., Gribben, J.G., Tooze, R. ORCID: https://orcid.org/0000-0003-2915-7119, Fitzgibbon, J., Franzoso, G., Rajewsky, K. and Calado, D.P. ORCID: https://orcid.org/0000-0001-8239-7184
bioRxiv
: 2020.04.12.038414.
13 April 2020
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Barone, M. ORCID: https://orcid.org/0000-0002-6554-6464, Müller, M., Chiha, S., Ren, J., Albat, D., Soicke, A., Dohmen, S., Klein, M., Bruns, J., van Dinther, M., Opitz, R. ORCID: https://orcid.org/0000-0003-3143-0997, Lindemann, P. ORCID: https://orcid.org/0000-0002-8224-3764, Beerbaum, M., Motzny, K., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Schmieder, P. ORCID: https://orcid.org/0000-0001-9968-9327, Volkmer, R., Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Oschkinat, H., Ten Dijke, P., Schmalz, H.G. ORCID: https://orcid.org/0000-0003-0489-1827 and Kühne, R.
Proceedings of the National Academy of Sciences of the United States of America 117
(47): 29684-29690.
24 November 2020
Enhancement of CRISPR-Cas9 induced precise gene editing by targeting Histone H2A-K15 ubiquitination.
Bashir, S. ORCID: https://orcid.org/0000-0002-1281-8710, Dang, T. ORCID: https://orcid.org/0009-0001-0138-7599, Rossius, J. ORCID: https://orcid.org/0009-0000-6011-9714, Wolf, J. and Kuehn, R. ORCID: https://orcid.org/0000-0003-1694-9803
BMC Biotechnology 20
(1): 57.
23 October 2020
Unblending of transcriptional condensates in human repeat expansion disease.
Basu, S., Mackowiak, S.D. ORCID: https://orcid.org/0000-0003-1673-5389, Niskanen, H., Knezevic, D., Asimi, V., Grosswendt, S. ORCID: https://orcid.org/0000-0001-7722-2937, Geertsema, H., Ali, S., Jerković, I., Ewers, H., Mundlos, S., Meissner, A., Ibrahim, D.M. and Hnisz, D.
Cell 181
(5): 1062-1079.
28 May 2020
Establishment of kidney cancer organoid cultures.
Bauer, D. ORCID: https://orcid.org/0000-0002-2933-4333, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Fendler, A. ORCID: https://orcid.org/0000-0002-7267-0981
Research Square
: rs.3.pex-911.
12 May 2020
LoopDetect: comprehensive feedback loop detection in ordinary differential equation models.
Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
bioRxiv
: 2020.11.15.383703.
17 November 2020
Analysing central metabolism in ultra-high resolution: at the crossroads of carbon and nitrogen.
Bayram, S. ORCID: https://orcid.org/0009-0009-5245-5473, Fürst, S., Forbes, M. ORCID: https://orcid.org/0000-0001-7775-8352 and Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299
Molecular Metabolism 33
: 38-47.
19 March 2020
Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia.
Becker, H. ORCID: https://orcid.org/0000-0002-6919-4048, Pfeifer, D., Ihorst, G., Pantic, M., Wehrle, J., Rüter, B.H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Hackanson, B., Germing, U., Kuendgen, A., Platzbecker, U., Döhner, K., Ganser, A., Hagemeijer, A., Wijermans, P.W., Döhner, H., Duyster, J. and Lübbert, M.
Annals of Hematology 99
(7): 1551-1560.
July 2020
Disentangling pro-mitotic signaling during cell cycle progression using time-resolved single-cell imaging.
Benary, M. ORCID: https://orcid.org/0000-0002-3067-2030, Bohn, S., Lüthen, M., Nolis, I.K., Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447 and Loewer, A. ORCID: https://orcid.org/0000-0002-8819-3040
Cell Reports 31
(2): 107514.
14 April 2020
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19.
Bernardes, J.P., Mishra, N., Tran, F., Bahmer, T., Best, L., Blase, J.I., Bordoni, D., Franzenburg, J., Geisen, U., Josephs-Spaulding, J., Köhler, P., Künstner, A., Rosati, E., Aschenbrenner, A.C., Bacher, P., Baran, N., Boysen, T., Brandt, B., Bruse, N., Dörr, J., Dräger, A., Elke, G., Ellinghaus, D., Fischer, J., Forster, M., Franke, A., Franzenburg, S., Frey, N., Friedrichs, A., Fuß, J., Glück, A., Hamm, J., Hinrichsen, F., Hoeppner, M.P., Imm, S., Junker, R., Kaiser, S., Kan, Y.H., Knoll, R., Lange, C., Laue, G., Lier, C., Lindner, M., Marinos, G., Markewitz, R., Nattermann, J., Noth, R., Pickkers, P., Rabe, K.F., Renz, A., Röcken, C., Rupp, J., Schaffarzyk, A., Scheffold, A., Schulte-Schrepping, J., Schunk, D., Skowasch, D., Ulas, T., Wandinger, K.P., Wittig, M., Zimmermann, J., Busch, H., Hoyer, B.F., Kaleta, C., Heyckendorf, J., Kox, M., Rybniker, J., Schreiber, S., Schultze, J.L. and Rosenstiel, P.
Immunity 53
(6): 1296-1314.
15 December 2020
Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer.
Berndt, N., Egners, A., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Vvedenskaya, O. ORCID: https://orcid.org/0000-0001-7808-269X, Fragoulis, A., Dugourd, A., Bulik, S., Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511, Bielow, C. ORCID: https://orcid.org/0000-0001-5756-3988, van Gassel, R., Olde Damink, S.W., Erdem, M., Saez-Rodriguez, J., Holzhütter, H.G., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Cramer, T.
British Journal of Cancer 122
(2): 233-244.
21 January 2020
SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
Biederstädt, A., Hassan, Z., Schneeweis, C., Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Schneider, L., Muckenhuber, A., Hong, Y., Siegers, G., Nilsson, L., Wirth, M., Dantes, Z., Steiger, K., Schunck, K., Langston, S., Lenhof, H.P., Coluccio, A., Orben, F., Slawska, J., Scherger, A., Saur, D., Müller, S., Rad, R., Weichert, W., Nilsson, J., Reichert, M. ORCID: https://orcid.org/0000-0002-8611-5639, Schneider, G. ORCID: https://orcid.org/0000-0003-1840-4508 and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Gut 69
(8): 1472-1482.
August 2020
Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis.
Bogdanow, B. ORCID: https://orcid.org/0000-0002-9634-7353, Schmidt, M., Weisbach, H., Gruska, I. ORCID: https://orcid.org/0000-0002-9539-609X, Vetter, B., Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Ostermann, E. ORCID: https://orcid.org/0000-0002-7539-2155, Brune, W. ORCID: https://orcid.org/0000-0002-6078-5255, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Hagemeier, C. and Wiebusch, L. ORCID: https://orcid.org/0000-0002-7210-6731
Nature Communications 11
(1): 4845.
24 September 2020
VISOR: a versatile haplotype-aware structural variant simulator for short- and long-read sequencing.
Bolognini, D. ORCID: https://orcid.org/0000-0002-8735-8093, Sanders, A. ORCID: https://orcid.org/0000-0003-3945-0677, Korbel, J.O., Magi, A., Benes, V. and Rausch, T. ORCID: https://orcid.org/0000-0001-5773-5620
Bioinformatics 36
(4): 1267-1269.
15 February 2020
Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial.
Bröckelmann, P.J., Goergen, H., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Meissner, J., Ordemann, R., Halbsguth, T.V., Sasse, S., Sökler, M., Kerkhoff, A., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Hüttmann, A., Bormann, M., Zimmermann, A., Mettler, J., Fuchs, M., von Tresckow, B., Baues, C., Rosenwald, A., Klapper, W., Kobe, C., Borchmann, P. and Engert, A.
JAMA Oncology 6
(6): 872-880.
June 2020
mRNAs, proteins and the emerging principles of gene expression control.
Buccitelli, C. ORCID: https://orcid.org/0000-0002-2637-2131 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Nature Reviews Genetics 21
(10): 630-644.
October 2020
Decoding and targeting the molecular basis of MACC1-driven metastatic spread: lessons from big data mining and clinical-experimental approaches.
Budczies, J., Kluck, K., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Seminars in Cancer Biology 60
: 365-379.
February 2020
NF-κB signaling in tanycytes mediates inflammation-induced anorexia.
Böttcher, M., Müller-Fielitz, H., Sundaram, S.M., Gallet, S., Neve, V., Shionoya, K., Zager, A., Quan, N., Liu, X., Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Haenold, R., Wenzel, J., Blomqvist, A., Engblom, D., Prevot, V. and Schwaninger, M.
Molecular Metabolism 39
: 101022.
September 2020
Human and mouse essentiality screens as a resource for disease gene discovery.
Cacheiro, P. ORCID: https://orcid.org/0000-0002-6335-8208, Muñoz-Fuentes, V. ORCID: https://orcid.org/0000-0003-3574-546X, Murray, S.A., Dickinson, M.E., Bucan, M., Nutter, L.M.J. ORCID: https://orcid.org/0000-0001-9619-146X, Peterson, K.A. ORCID: https://orcid.org/0000-0001-8353-3694, Haselimashhadi, H. ORCID: https://orcid.org/0000-0001-7334-2421, Flenniken, A.M., Morgan, H., Westerberg, H., Konopka, T. ORCID: https://orcid.org/0000-0003-3042-4712, Hsu, C.W. ORCID: https://orcid.org/0000-0002-9591-9567, Christiansen, A., Lanza, D.G. ORCID: https://orcid.org/0000-0001-8750-6933, Beaudet, A.L., Heaney, J.D. ORCID: https://orcid.org/0000-0001-8475-8828, Fuchs, H. ORCID: https://orcid.org/0000-0002-5143-2677, Gailus-Durner, V. ORCID: https://orcid.org/0000-0002-6076-0111, Sorg, T., Prochazka, J., Novosadova, V., Lelliott, C.J. ORCID: https://orcid.org/0000-0001-8087-4530, Wardle-Jones, H., Wells, S., Teboul, L., Cater, H., Stewart, M., Hough, T., Wurst, W., Sedlacek, R., Adams, D.J. ORCID: https://orcid.org/0000-0001-9490-0306, Seavitt, J.R., Tocchini-Valentini, G., Mammano, F. ORCID: https://orcid.org/0000-0003-3751-1691, Braun, R.E., McKerlie, C. ORCID: https://orcid.org/0000-0002-2232-0967, Herault, Y. ORCID: https://orcid.org/0000-0001-7049-6900, de Angelis, M.H. ORCID: https://orcid.org/0000-0002-7898-2353, Mallon, A.M., Lloyd, K.C.K. ORCID: https://orcid.org/0000-0002-5318-4144, Brown, S.D.M., Parkinson, H., Meehan, T.F. and Smedley, D. ORCID: https://orcid.org/0000-0002-5836-9850
Nature Communications 11
(1): 655.
31 January 2020
Genomic basis for RNA alterations in cancer.
Calabrese, C., Davidson, N.R., Demircioğlu, D., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., Soulette, C.M., Urban, L., Greger, L., Li, S., Liu, D., Perry, M.D., Xiang, Q., Zhang, F., Zhang, J., Bailey, P., Erkek, S., Hoadley, K.A., Hou, Y., Huska, M.R. ORCID: https://orcid.org/0000-0002-0912-745X, Kilpinen, H., Korbel, J.O., Marin, M.G., Markowski, J. ORCID: https://orcid.org/0000-0002-0573-7832, Nandi, T., Pan-Hammarström, Q., Pedamallu, C.S., Siebert, R., Stark, S.G., Su, H., Tan, P., Waszak, S.M., Yung, C., Zhu, S., Awadalla, P., Creighton, C.J., Meyerson, M., Ouellette, B.F.F., Wu, K., Yang, H., Brazma, A., Brooks, A.N., Göke, J., Rätsch, G., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Stegle, O. and Zhang, Z.
Nature 578
(7793): 129-136.
6 February 2020
Quantification of translation uncovers the functions of the alternative transcriptome.
Calviello, L. ORCID: https://orcid.org/0000-0002-5600-0988, Hirsekorn, A. and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Nature Structural & Molecular Biology 27
(8): 717-725.
August 2020
Single-cell lineage tracing approaches in hematology research: technical considerations.
Carrelha, J., Lin, D.S., Rodriguez-Fraticelli, A.E., Luis, T.C., Wilkinson, A.C., Cabezas-Wallscheid, N., Tremblay, C.S. and Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Experimental Hematology 89
: 26-36.
September 2020
Structure of RyR1 in native membranes.
Chen, W. and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
EMBO Reports 21
(5): e49891.
6 May 2020
What is extrachromosomal circular DNA and what does it do?
Chiu, R.W.K., Dutta, A., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Lo, Y.M.D., Mischel, P. and Regenberg, B.
Clinical Chemistry 66
(6): 754-759.
June 2020
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chong, C., Müller, M. ORCID: https://orcid.org/0000-0003-0907-3583, Pak, H.S., Harnett, D. ORCID: https://orcid.org/0000-0002-9190-128X, Huber, F., Grun, D., Leleu, M., Auger, A., Arnaud, M., Stevenson, B.J., Michaux, J., Bilic, I. ORCID: https://orcid.org/0000-0002-2730-1634, Hirsekorn, A., Calviello, L. ORCID: https://orcid.org/0000-0002-5600-0988, Simó-Riudalbas, L., Planet, E., Lubiński, J., Bryśkiewicz, M., Wiznerowicz, M. ORCID: https://orcid.org/0000-0003-4960-6321, Xenarios, I., Zhang, L. ORCID: https://orcid.org/0000-0003-1998-0611, Trono, D., Harari, A. ORCID: https://orcid.org/0000-0002-1055-2090, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Coukos, G. ORCID: https://orcid.org/0000-0001-8813-7367 and Bassani-Sternberg, M. ORCID: https://orcid.org/0000-0002-1934-954X
Nature Communications 11
(1): 1293.
10 March 2020
Structure of the active GGEEF domain of a diguanylate cyclase from Vibrio cholerae.
Chouhan, O.P., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Biswas, S.
Biochemical and Biophysical Research Communications 523
(2): 287-292.
5 March 2020
Endothelial damage and dysfunction in acute graft-versus-host disease.
Cordes, S., Mokhtari, Z., Bartosova, M., Mertlitz, S., Riesner, K., Shi, Y., Mengwasser, J., Kalupa, M., McGeary, A., Schleifenbaum, J. ORCID: https://orcid.org/0000-0002-3195-1517, Schrezenmeier, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Diaz-Ricart, M., Palomo, M., Carrreras, E., Beutel, G., Schmitt, C.P., Beilhack, A. and Penack, O.
Haematologica 106
(8): 2147-2160.
1 August 2020
A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis.
Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Doll, S., Bech, J.M., Schweizer, L., Mund, A., Lengyel, E., Lindebjerg, J., Madsen, G.I., Moreira, J.M. and Mann, M.
Journal of Pathology 251
(1): 100-112.
May 2020
Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription.
Cossa, G., Roeschert, I., Prinz, F., Baluapuri, A., Silveira Vidal, R., Schülein-Völk, C., Chang, Y.C., Ade, C.P., Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Girard, C., Kumar, A., Wortmann, L., Walz, S., Lührmann, R., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Kuster, B., Wolf, E., Mumberg, D. and Eilers, M.
Molecular Cell 77
(6): 1322-1339.
19 March 2020
Restoring treatment response in colorectal cancer cells by targeting MACC1-dependent ABCB1 expression in combination therapy.
Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Werner, R., Kortüm, B. ORCID: https://orcid.org/0000-0003-3734-6665, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Frontiers in Oncology 10
: 599.
23 April 2020
Novel targets of protoporphyrin-IX determined by gene expression analysis.
Dai, Y. and Kemmner, W. ORCID: https://orcid.org/0000-0002-1494-7225
International Journal of Clinical Oncology and Cancer Research 5
(3): 56-64.
September 2020
The pierced lasso topology leptin has a bolt on dynamic domain composed by the disordered loops I and III.
Danielsson, J., Noel, J.K. ORCID: https://orcid.org/0000-0003-3168-6036, Simien, J.M., Duggan, B.M., Oliveberg, M., Onuchic, J.N., Jennings, P.A. and Haglund, E.
Journal of Molecular Biology 432
(9): 3050-3063.
17 April 2020
TIM-3 and CEACAM1 do not interact in cis and in trans.
De Sousa Linhares, A., Kellner, F. ORCID: https://orcid.org/0000-0001-5931-3798, Jutz, S., Zlabinger, G.J. ORCID: https://orcid.org/0000-0002-7478-4173, Gabius, H.J., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Leitner, J. ORCID: https://orcid.org/0000-0002-7156-1759 and Steinberger, P. ORCID: https://orcid.org/0000-0001-6848-4097
European Journal of Immunology 50
(8): 1126-1141.
August 2020
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V. ORCID: https://orcid.org/0000-0002-0077-1935, Berruezo-Llacuna, M., Altwasser, R. ORCID: https://orcid.org/0009-0002-6216-6068, Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Sundaravinayagam, D. ORCID: https://orcid.org/0000-0003-0717-7530, Balasubramanian, S. ORCID: https://orcid.org/0000-0003-1830-5737, Caganova, M. ORCID: https://orcid.org/0000-0002-4576-6574, Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Rahjouei, A. ORCID: https://orcid.org/0000-0003-3973-6333, Henke, M.T. ORCID: https://orcid.org/0000-0001-6572-1667, Driesner, M., Keller, L., Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793
Journal of Experimental Medicine 217
(10): e20200137.
5 October 2020
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P., Newman, A.G. ORCID: https://orcid.org/0000-0002-0222-9162, Singh, M. ORCID: https://orcid.org/0000-0002-8626-5418, Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121, Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T. ORCID: https://orcid.org/0000-0001-7512-8955, Wallach, T., Kleinau, G., Derkow, K., Richard, B.C., Schipke, C. ORCID: https://orcid.org/0000-0002-1105-1853, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Stachelscheid, H., Golenbock, D., Peters, O. ORCID: https://orcid.org/0000-0003-0568-2998, Coleman, M., Heppner, F.L., Scheerer, P., Tarabykin, V., Ruprecht, K., Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384, Mayer, J. and Lehnardt, S.
JCI Insight 5
(7): e131093.
9 April 2020
Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.
Dias D'Andréa, E., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, de Oliveira, G.A.P., Cremer, N., Diehl, A., Schmieder, P. ORCID: https://orcid.org/0000-0001-9968-9327, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Oschkinat, H. and Ricardo Pires, J.
Journal of Structural Biology 211
(2): 107536.
1 August 2020
Functional classification of TP53 mutations in acute myeloid leukemia.
Dutta, S., Pregartner, G., Rücker, F.G., Heitzer, E. ORCID: https://orcid.org/0000-0002-8815-7859, Zebisch, A. ORCID: https://orcid.org/0000-0002-4861-7021, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Berghold, A., Döhner, K. and Sill, H. ORCID: https://orcid.org/0000-0003-0993-4371
Cancers 12
(3): 637.
10 March 2020
Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin.
Dyring-Andersen, B., Løvendorf, M.B., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Santos, A., Møller, L.B.P., Colaço, A.R., Niu, L., Bzorek, M., Doll, S., Andersen, J.L., Clark, R.A., Skov, L. ORCID: https://orcid.org/0000-0002-4784-9680, Teunissen, M.B.M. ORCID: https://orcid.org/0000-0003-1119-6662 and Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799
Nature Communications 11
(1): 5587.
5 November 2020
Longtime outcome after intraosseous application of autologous mesenchymal stromal cells in pediatric patients and young adults with avascular necrosis after steroid or chemotherapy.
Döring, M., Kluba, T., Cabanillas Stanchi, K.M., Kahle, P., Lenglinger, K., Tsiflikas, I., Treuner, C., Vaegler, M. ORCID: https://orcid.org/0009-0005-3852-4525, Mezger, M., Erbacher, A., Schumm, M., Lang, P., Handgretinger, R. and Müller, I.
Stem Cells and Development 29
(13): 811-822.
July 2020
Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Edelmann, J., Holzmann, K., Tausch, E., Saunderson, E.A., Jebaraj, B.M.C., Steinbrecher, D., Dolnik, A., Blätte, T.J., Landau, D.A., Saub, J., Estenfelder, S., Ibach, S., Cymbalista, F., Leblond, V., Delmer, A., Bahlo, J., Robrecht, S., Fischer, K., Goede, V., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Wu, C.J., Mertens, D., Ficz, G., Gribben, J.G., Hallek, M., Döhner, H. and Stilgenbauer, S.
Haematologica 105
(5): 1379-1390.
May 2020
Age attenuates the T-type Ca(V) 3.2-RyR axis in vascular smooth muscle.
Fan, G. ORCID: https://orcid.org/0000-0003-1894-3253, Kaßmann, M. ORCID: https://orcid.org/0000-0002-4785-6530, Cui, Y., Matthaeus, C. ORCID: https://orcid.org/0000-0003-3242-1195, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Zhong, C., Zhu, S., Xie, Yu, Tsvetkov, D. ORCID: https://orcid.org/0000-0002-6472-971X, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Huang, Yu and Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934
Aging Cell 19
(4): e13134.
April 2020
Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients.
Fendler, A. ORCID: https://orcid.org/0000-0002-7267-0981, Bauer, D. ORCID: https://orcid.org/0000-0002-2933-4333, Busch, J., Jung, K. ORCID: https://orcid.org/0000-0001-9797-5362, Wulf-Goldenberg, A., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Song, K. ORCID: https://orcid.org/0000-0001-6216-8157, Myszczyszyn, A. ORCID: https://orcid.org/0009-0006-6152-5451, Elezkurtaj, S. ORCID: https://orcid.org/0000-0003-1219-6517, Erguen, B., Jung, S., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Nature Communications 11
(1): 929.
17 February 2020
CD8-specific designed ankyrin repeat proteins improve selective gene delivery into human and primate T lymphocytes.
Frank, A.M., Weidner, T., Brynza, J., Uckert, W., Buchholz, C.J. and Hartmann, J.
Human Gene Therapy 31
(11-12): 679-691.
June 2020
A conserved noncoding locus regulates random monoallelic Xist expression across a topological boundary.
Galupa, R., Nora, E.P., Worsley-Hunt, R., Picard, C., Gard, C., van Bemmel, J.G., Servant, N., Zhan, Y., El Marjou, F., Johanneau, C., Diabangouaya, P., Le Saux, A., Lameiras, S., Pipoli da Fonseca, J., Loos, F., Gribnau, J., Baulande, S., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Giorgetti, L. and Heard, E.
Molecular Cell 77
(2): 352-367.
16 January 2020
pH-dependent protonation of surface carboxylate groups in PsbO enables local buffering and triggers structural changes.
Gerland, L. M., Friedrich, D., Hopf, L. ORCID: https://orcid.org/0000-0002-4372-694X, Donovan, E., Wallmann, A., Erdmann, N., Diehl, A., Bommer, M., Buzar, K., Ibrahim, M., Schmieder, P. ORCID: https://orcid.org/0000-0001-9968-9327, Dobbek, H., Zouni, A., Bondar, A.-N., Dau, H. and Oschkinat, H.
ChemBioChem 21
(11): 1597-1604.
2 June 2020
Deep neural networks for interpreting RNA-binding protein target preferences.
Ghanbari, M. ORCID: https://orcid.org/0000-0002-6015-2968 and Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116
Genome Research 30
(2): 214-226.
February 2020
Cxcl10(+) monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation.
Giladi, A. ORCID: https://orcid.org/0000-0002-5880-2845, Wagner, L.K., Li, H., Dörr, D. ORCID: https://orcid.org/0000-0001-8575-7560, Medaglia, C., Paul, F., Shemer, A., Jung, S. ORCID: https://orcid.org/0000-0003-4290-5716, Yona, S., Mack, M., Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X, Amit, I. ORCID: https://orcid.org/0000-0003-2968-877X and Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427
Nature Immunology 21
(5): 525-534.
May 2020
GPSeq reveals the radial organization of chromatin in the cell nucleus.
Girelli, G. ORCID: https://orcid.org/0000-0003-4264-6494, Custodio, J., Kallas, T., Agostini, F. ORCID: https://orcid.org/0000-0002-5453-2737, Wernersson, E. ORCID: https://orcid.org/0000-0003-4778-1660, Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Mota, A., Kolbeinsdottir, S., Gelali, E. ORCID: https://orcid.org/0000-0003-0067-5473, Crosetto, N. ORCID: https://orcid.org/0000-0002-3019-6978 and Bienko, M. ORCID: https://orcid.org/0000-0002-6499-9082
Nature Biotechnology 38
(10): 1184-1193.
October 2020
Lymphoma angiogenesis is orchestrated by noncanonical signaling pathways.
Gloger, M. ORCID: https://orcid.org/0000-0002-3319-7642, Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Grau, M., Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Anagnostopoulos, I., Zapukhlyak, M., Gerlach, K., Kammertöns, T. ORCID: https://orcid.org/0000-0003-3309-5141, Hehlgans, T., Zschummel, M. ORCID: https://orcid.org/0000-0002-4778-8742, Lenz, G., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Cancer Research 80
(6): 1316-1329.
March 2020
The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Grasedieck, S., Ruess, C., Krowiorz, K., Lux, S., Pochert, N., Schwarzer, A., Klusmann, J.H., Jongen-Lavrencic, M., Herold, T., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Pollack, J.R., Rouhi, A. and Kuchenbauer, F.
Haematologica 105
(9): e448-e453.
September 2020
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.
Greiner, J. ORCID: https://orcid.org/0000-0003-1256-173X, Götz, M., Hofmann, S., Schrezenmeier, H., Wiesneth, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, H. and Schneider, V.
Cancer Immunology Immunotherapy 69
(4): 629-640.
April 2020
Ensuring center quality, proper patient selection and fair access to chimeric antigen receptor T-cell therapy: position statement of the Austrian CAR-T Cell Network.
Greinix, H.T., Attarbaschi, A., Girschikofsky, M., Greil, R., Holter, W., Neumeister, P., Peters, C., Petzer, A., Rudzki, J., Schlenke, P., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Schwinger, W., Wolf, D., Worel, N. and Jaeger, U.
memo: Magazine of European Medical Oncology 13
(1): 27-31.
March 2020
The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat, J. ORCID: https://orcid.org/0000-0003-0152-4941, Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Vidal, R. ORCID: https://orcid.org/0000-0003-4217-2014, Goveas, N. ORCID: https://orcid.org/0000-0002-2531-5514, Kosel, F., Berenguer-Llergo, A. ORCID: https://orcid.org/0000-0002-3742-8161, Kranz, A., Wulf-Goldenberg, A., Behrens, D., Melcher, B., Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Vieth, M., Batlle, E., Stewart, A. and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Nature Communications 11
(1): 6422.
21 December 2020
Mechanism of virus attenuation by codon pair deoptimization.
Groenke, N. ORCID: https://orcid.org/0000-0002-6927-3774, Trimpert, J., Merz, S., Conradie, A.M., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Zhang, H., Hazapis, O.G., Rausch, S., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Osterrieder, N. and Kunec, D. ORCID: https://orcid.org/0000-0001-6697-7621
Cell Reports 31
(4): 107586.
28 April 2020
Epigenetic regulator function through mouse gastrulation.
Grosswendt, S. ORCID: https://orcid.org/0000-0001-7722-2937, Kretzmer, H., Smith, Z.D., Kumar, A.S., Hetzel, S., Wittler, L., Klages, S., Timmermann, B., Mukherji, S. and Meissner, A.
Nature 584
(7819): 102-108.
6 August 2020
Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Hopf, L.V.M. ORCID: https://orcid.org/0000-0002-4372-694X, Bock-Bierbaum, T. ORCID: https://orcid.org/0000-0003-0843-2716, Lally, C.C.M., Spahn, C.M.T. and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Nature Communications 11
(1): 5506.
2 November 2020
Sarcoma treatment in the era of molecular medicine.
Grünewald, T.G.P. ORCID: https://orcid.org/0000-0003-0920-7377, Alonso, M. ORCID: https://orcid.org/0000-0002-7520-7351, Avnet, S., Banito, A., Burdach, S., Cidre-Aranaz, F. ORCID: https://orcid.org/0000-0002-0246-7179, Di Pompo, G., Distel, M., Dorado-Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Garcia-Castro, J., González-González, L., Grigoriadis, A.E., Kasan, M., Koelsche, C., Krumbholz, M., Lecanda, F., Lemma, S., Longo, D.L., Madrigal-Esquivel, C., Morales-Molina, Á., Musa, J., Ohmura, S., Ory, B., Pereira-Silva, M., Perut, F., Rodriguez, R. ORCID: https://orcid.org/0000-0002-0768-7306, Seeling, C., Al Shaaili, N., Shaabani, S., Shiavone, K., Sinha, S., Tomazou, E.M., Trautmann, M. ORCID: https://orcid.org/0000-0002-5842-1196, Vela, M., Versleijen-Jonkers, Y.M.H., Visgauss, J., Zalacain, M., Schober, S.J., Lissat, A., English, W.R., Baldini, Ni. ORCID: https://orcid.org/0000-0003-2228-3833 and Heymann, D. ORCID: https://orcid.org/0000-0001-7777-0669
EMBO Molecular Medicine 12
: e11131.
6 November 2020
Inefficient CAR-proximal signaling blunts antigen sensitivity.
Gudipati, V. ORCID: https://orcid.org/0000-0001-6647-0708, Rydzek, J., Doel-Perez, I. ORCID: https://orcid.org/0000-0003-0443-9718, Gonçalves, V.D.R. ORCID: https://orcid.org/0000-0001-9982-3346, Scharf, L. ORCID: https://orcid.org/0000-0002-1596-2208, Königsberger, S., Lobner, E. ORCID: https://orcid.org/0000-0002-5234-5524, Kunert, R. ORCID: https://orcid.org/0000-0002-3397-3621, Einsele, H., Stockinger, H. ORCID: https://orcid.org/0000-0001-6404-4430, Hudecek, M. ORCID: https://orcid.org/0000-0002-2280-2202 and Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198
Nature Immunology 21
(8): 848-856.
August 2020
Saffron crudes and compounds restrict MACC1-dependent cell proliferation and migration of colorectal cancer cells.
Güllü, N., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Brim, H., Rahman, S., Timm, L., Smith, J., Soleimani, A., Di Marco, S. ORCID: https://orcid.org/0000-0003-4847-6270, Bisti, S., Ashktorab, H. ORCID: https://orcid.org/0000-0002-4048-4666 and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Cells 9
(8): 1829.
3 August 2020
Hematopoietic stem cells in health and disease - insights from single-cell multi-omic approaches.
Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051
Current Stem Cell Reports 6
(3): 67-76.
September 2020
Karzinogenese: Big Bang oder kontinuierliche Evolution?
Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618 and Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268
BIOspektrum 26
(7): 718-720.
November 2020
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M. ORCID: https://orcid.org/0000-0001-7132-8079, Pablo-Tortola, C., Todiras, M. ORCID: https://orcid.org/0000-0002-9373-4753, Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M. ORCID: https://orcid.org/0000-0002-0513-3254, Jarosch, E. ORCID: https://orcid.org/0000-0002-5897-3492, Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202, Bröker, B.M., Felix, S.B., Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Weber-Carstens, S., Butter, C., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 11
(1): 103-119.
February 2020
Microbe-driven genotoxicity in gastrointestinal carcinogenesis.
Hartl, K. ORCID: https://orcid.org/0000-0002-2965-0512 and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
International Journal of Molecular Sciences 21
(20): 7439.
2 October 2020
High-risk additional chromosomal abnormalities at low blast counts herald death by CML.
Hehlmann, R., Voskanyan, A., Lauseker, M., Pfirrmann, M., Kalmanti, L., Rinaldetti, S., Kohlbrenner, K., Haferlach, C., Schlegelberger, B., Fabarius, A., Seifarth, W., Spieß, B., Wuchter, P., Krause, S. ORCID: https://orcid.org/0000-0002-5259-4651, Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Burchert, A., Brümmendorf, T.H., Hasford, J., Hochhaus, A., Saußele, S. and Baccarani, M.
Leukemia 34
(8): 2074-2086.
August 2020
Symmetry in nucleic-acid double helices.
Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X
Symmetry 12
(5): 737.
5 May 2020
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Valieva, M.E. ORCID: https://orcid.org/0000-0002-4419-2839, Ali, S. ORCID: https://orcid.org/0000-0002-0351-1645, Chamorro Gonzalez, R. ORCID: https://orcid.org/0000-0002-5653-7259, Schöpflin, R., Röefzaad, C. ORCID: https://orcid.org/0000-0003-2299-6673, Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Puiggròs, M. ORCID: https://orcid.org/0000-0001-5034-7924, Kasack, K., Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Keskeny, C. ORCID: https://orcid.org/0000-0003-3297-7329, Chen, C.Y. ORCID: https://orcid.org/0000-0002-1579-024X, Kuschel, L.P. ORCID: https://orcid.org/0000-0001-7794-2205, Euskirchen, P. ORCID: https://orcid.org/0000-0002-9138-805X, Heinrich, V., Robson, M.I. ORCID: https://orcid.org/0000-0003-1126-3538, Rosswog, C., Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242, Torrents, D., Eggert, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Mundlos, S., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X and Koche, R.P. ORCID: https://orcid.org/0000-0002-6820-5083
Nature Communications 11
(1): 5823.
16 November 2020
CXCR4-targeted PET imaging of central nervous system B-cell lymphoma.
Herhaus, P., Lipkova, J., Lammer, F., Yakushev, I., Vag, T., Slotta-Huspenina, J., Habringer, S. ORCID: https://orcid.org/0000-0002-3976-9592, Lapa, C., Pukrop, T., Hellwig, D., Wiestler, B., Buck, A.K., Deckert, M., Wester, H.J., Bassermann, F., Schwaiger, M., Weber, W.A., Menze, B. and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Journal of Nuclear Medicine 61
(12): 1765-1771.
1 December 2020
Final results of a phase I/II trial of the combination Bendamustine and Rituximab with Temsirolimus (BeRT) in relapsed mantle cell lymphoma and follicular lymphoma.
Hess, G., Wagner, K., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, La Rosee, P., Atta, J., Hübel, K., Lerchenmueller, C., Schoendube, D., Witzens-Harig, M., Ruckes, C., Medler, C., van Oordt, C., Klapper, W., Theobald, M. and Dreyling, M.
HemaSphere 4
(3): e398.
June 2020
FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease.
Hoffmann, S., Pentakota, S., Mund, A., Haahr, P., Coscia, F. ORCID: https://orcid.org/0000-0002-2244-5081, Gallo, M., Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799, Taylor, N.M. ORCID: https://orcid.org/0000-0003-0761-4921 and Mailand, N. ORCID: https://orcid.org/0000-0002-6623-709X
EMBO Reports 21
(10): e50662.
5 October 2020
MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma.
Hohmann, T. ORCID: https://orcid.org/0000-0002-0304-7221, Hohmann, U., Kolbe, M.R., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Dehghani, F.
Cell Communication and Signaling 18
(1): 85.
5 June 2020
Authentication of primary murine cell lines by a microfluidics-based lab-on-chip system.
Hong, Y., Singh, N., Bamopoulos, S., Gjerga, E., Schmalbrock, L.K. ORCID: https://orcid.org/0000-0002-6080-6175, Balabanian, K. ORCID: https://orcid.org/0000-0002-0534-3198, Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872
Biomedicines 8
(12): 590.
9 December 2020
FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells.
Hu, J.L., Liang, H., Zhang, H., Yang, M.Z., Sun, W. ORCID: https://orcid.org/0000-0001-9607-1361, Zhang, P., Luo, L., Feng, J.X., Bai, H., Liu, F., Zhang, T., Yang, J.Y. ORCID: https://orcid.org/0000-0003-0953-7325, Gao, Q. ORCID: https://orcid.org/0000-0002-9930-8499, Long, Y., Ma, X.Y., Chen, Y., Zhong, Q., Yu, B., Liao, S., Wang, Y., Zhao, Y., Zeng, M.S. ORCID: https://orcid.org/0000-0003-3509-5591, Cao, N., Wang, J., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Yang, H.T. and Gao, S. ORCID: https://orcid.org/0000-0001-7427-6681
Nucleic Acids Research 48
(5): 2733-2748.
18 March 2020
Local and central evaluation of HER2 positivity and clinical outcome in advanced gastric and gastroesophageal cancer: results from the AGMT GASTRIC-5 Registry.
Huemer, F., Weiss, L. ORCID: https://orcid.org/0000-0002-2174-5613, Regitnig, P. ORCID: https://orcid.org/0000-0002-1371-1595, Winder, T., Hartmann, B., Thaler, J., Piringer, G., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Eisterer, W., Gänzer, H., Wüstner, Al., Andel, J., Jagdt, B., Ulmer, H., Greil, R. ORCID: https://orcid.org/0000-0002-4462-3694 and Wöll, E.
Journal of Clinical Medicine 9
(4): 935.
29 March 2020
The International Virus Bioinformatics Meeting 2020.
Hufsky, F. ORCID: https://orcid.org/0000-0002-9489-3182, Beerenwinkel, N. ORCID: https://orcid.org/0000-0002-0573-6119, Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479, Roux, S. ORCID: https://orcid.org/0000-0002-5831-5895, Cook, G.M., Kinsella, C.M. ORCID: https://orcid.org/0000-0001-9865-4608, Lamkiewicz, K. ORCID: https://orcid.org/0000-0002-6375-6441, Marquet, M., Nieuwenhuijse, D.F. ORCID: https://orcid.org/0000-0003-1310-5031, Olendraite, I., Paraskevopoulou, S. ORCID: https://orcid.org/0000-0003-2608-2596, Young, F. ORCID: https://orcid.org/0000-0002-5236-1145, Dijkman, R. ORCID: https://orcid.org/0000-0003-0320-2743, Ibrahim, B. ORCID: https://orcid.org/0000-0001-7773-0122, Kelly, J., Le Mercier, P. ORCID: https://orcid.org/0000-0001-8528-090X, Marz, M., Ramette, A. ORCID: https://orcid.org/0000-0002-3437-4639 and Thiel, V. ORCID: https://orcid.org/0000-0002-5783-0887
Viruses 12
(12): 1398.
6 December 2020
Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia.
In't Hout, F.E.M., Gerritsen, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Van der Reijden, B.A., Huls, G., Vellenga, E. and Jansen, J.H.
Haematologica 105
(9): e454-457.
1 September 2020
Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.
Jahn, N., Terzer, T. ORCID: https://orcid.org/0000-0003-2495-3589, Sträng, E., Dolnik, A., Cocciardi, S., Panina, E., Corbacioglu, A., Herzig, J., Weber, D., Schrade, A., Götze, K. ORCID: https://orcid.org/0000-0002-6276-8002, Schröder, T., Lübbert, M., Wellnitz, D., Koller, E., Schlenk, R.F. ORCID: https://orcid.org/0000-0003-2215-2059, Gaidzik, V.I., Paschka, P., Rücker, F.G., Heuser, M., Thol, F., Ganser, A., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Döhner, H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Döhner, K.
Blood Advances 4
(24): 6342-6352.
22 December 2020
Cbl-Associated Protein CAP contributes to correct formation and robust function of the Drosophila heart tube.
Jammrath, J., Reim, I. and Saumweber, H. ORCID: https://orcid.org/0000-0003-3957-1612
PLoS ONE 15
(5): e0233719.
29 May 2020
A randomized open label phase-II clinical trial with or without infusion of plasma from subjects after convalescence of SARS-CoV-2 infection in high-risk patients with confirmed severe SARS-CoV-2 disease (RECOVER): a structured summary of a study protocol for a randomised controlled trial.
Janssen, M., Schäkel, U., Djuka Fokou, C., Krisam, J., Stermann, J., Kriegsmann, K., Haberbosch, I., Novotny, J.P., Weber, S., Vehreschild, M., Bornhäuser, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Schmitt, M., Liebregts, T., Dreger, P., Lorenz, H.M., Plaszczyca, A., Bartenschlager, R., Müller, B., Kräusslich, H.G., Halama, N., Jäger, D., Schlenk, R.F., Leo, A., Meuer, S., Weigand, M.A., Motsch, J., Merle, U., Denkinger, C.M. and Müller-Tidow, C.
Trials 21
(1): 828.
6 October 2020
Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Jayavelu, A.K., Schnöder, T.M., Perner, F., Herzog, C., Meiler, A. ORCID: https://orcid.org/0000-0003-0012-7952, Krishnamoorthy, G. ORCID: https://orcid.org/0000-0002-7798-6707, Huber, N., Mohr, J., Edelmann-Stephan, B., Austin, R., Brandt, S., Palandri, F. ORCID: https://orcid.org/0000-0001-8367-5668, Schröder, N., Isermann, B., Edlich, F., Sinha, A.U., Ungelenk, M., Hübner, C.A., Zeiser, R. ORCID: https://orcid.org/0000-0001-6565-3393, Rahmig, S., Waskow, C. ORCID: https://orcid.org/0000-0003-3261-0922, Coldham, I. ORCID: https://orcid.org/0000-0003-4602-6292, Ernst, T., Hochhaus, A., Jilg, S., Jost, P.J. ORCID: https://orcid.org/0000-0003-2454-0362, Mullally, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertens, P.R., Lane, S.W. ORCID: https://orcid.org/0000-0002-8050-6209, Mann, M. ORCID: https://orcid.org/0000-0003-1292-4799 and Heidel, F.H. ORCID: https://orcid.org/0000-0003-2438-1955
Nature 588
(7836): 157-163.
3 December 2020
Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions.
Jeuthe, S., Kemna, J. ORCID: https://orcid.org/0000-0002-2172-4441, Kemna, C.P., Zocholl, D., Klopfleisch, R., Palme, R. ORCID: https://orcid.org/0000-0001-9466-3662, Kirschbaum, C., Thoene-Reineke, C. and Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141
PLoS ONE 15
(9): e0239231.
30 September 2020
Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.
Jiang, S., Penack, O., Terzer, T., Schult, D., Majer-Lauterbach, J., Radujkovic, A., Blau, I.W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Müller-Tidow, C., Dreger, P. and Luft, T.
Haematologica 106
(2): 446-453.
February 2020
Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes.
Jumaa, H., Caganova, M. ORCID: https://orcid.org/0000-0002-4576-6574, McAllister, E.J., Hoenig, L., He, X., Saltukoglu, D. ORCID: https://orcid.org/0000-0003-0959-0812, Brenker, K., Köhler, M., Leben, R., Hauser, A.E., Niesner, R. ORCID: https://orcid.org/0000-0001-8969-5432, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Reth, M. and Jellusova, J. ORCID: https://orcid.org/0000-0002-5234-2104
Life Science Alliance 3
(6): e202000700.
June 2020
Identification of miR-21-5p and miR-210-3p serum levels as biomarkers for patients with papillary renal cell carcinoma: a multicenter analysis.
Kalogirou, C., Ellinger, J., Kristiansen, G., Hatzichristodoulou, G., Kübler, H., Kneitz, B., Busch, J. and Fendler, A. ORCID: https://orcid.org/0000-0002-7267-0981
Translational Andrology and Urology 9
(3): 1314-1322.
June 2020
"Designer cytokines" targeting the tumor vasculature - think global and act local.
Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141, Kemna, J. ORCID: https://orcid.org/0000-0002-2172-4441 and Leisegang, M. ORCID: https://orcid.org/0000-0003-3692-7142
EMBO Molecular Medicine 12
(2): e11801.
7 February 2020
Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Kapp-Schwoerer, S., Weber, D., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Krönke, J., Theis, F., Rücker, F.G., Teleanu, M.V., Panina, E., Jahn, N., Herzig, J., Kubanek, L., Schrade, A., Göhring, G., Fiedler, W., Kindler, T, Schroeder, T., Mayer, K.T., Lübbert, M., Wattad, M., Götze, K.S. ORCID: https://orcid.org/0000-0002-6276-8002, Horst, H.A., Koller, E., Wulf, G. ORCID: https://orcid.org/0000-0002-7669-3785, Schleicher, J., Bentz, M., Krauter, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Krzykalla, J., Benner, A. ORCID: https://orcid.org/0000-0002-7238-6956, Schlenk, R.F. ORCID: https://orcid.org/0000-0003-2215-2059, Thol, F., Heuser, M., Ganser, A., Döhner, H ORCID: https://orcid.org/0000-0003-2116-5536 and Döhner, K. ORCID: https://orcid.org/0000-0002-2261-9862
Blood 136
(26): 3041-3050.
24 December 2020
PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity.
Kim, H., Kim, H., Feng, Y., Li, Y., Tamiya, H., Tocci, S. and Ronai, Z.A.
Science Translational Medicine 12
(551): eaaz5683.
8 July 2020
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.
Kim, H. ORCID: https://orcid.org/0000-0003-4244-6126, Nguyen, N.P., Turner, K., Wu, S. ORCID: https://orcid.org/0000-0001-8329-7492, Gujar, A.D. ORCID: https://orcid.org/0000-0003-0689-6680, Luebeck, J. ORCID: https://orcid.org/0000-0003-4391-979X, Liu, J., Deshpande, V., Rajkumar, U., Namburi, S., Amin, S.B., Yi, E. ORCID: https://orcid.org/0000-0002-7839-7795, Menghi, F., Schulte, J.H., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Chang, H.Y. ORCID: https://orcid.org/0000-0002-9459-4393, Beck, C.R. ORCID: https://orcid.org/0000-0001-7821-8489, Mischel, .S. ORCID: https://orcid.org/0000-0002-4560-2211, Bafna, V. ORCID: https://orcid.org/0000-0002-5810-6241 and Verhaak, R.G.W. ORCID: https://orcid.org/0000-0003-2773-0436
Nature Genetics 52
(9): 891-897.
September 2020
Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer.
Klinghammer, K. ORCID: https://orcid.org/0000-0001-6425-4833, Politz, O., Eder, T., Otto, R., Raguse, J.D., Albers, A., Kaufmann, A., Tinhofer, I., Hoffmann, J. ORCID: https://orcid.org/0000-0003-3880-1658, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Keilholz, U.
Oncotarget 11
(41): 3688-3697.
13 October 2020
Small ones to fight a big problem-intervention of cancer metastasis by small molecules.
Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Dumbani, M., Güllü, N., Kortüm, B. ORCID: https://orcid.org/0000-0003-3734-6665, Vílchez, M.E.A. ORCID: https://orcid.org/0000-0002-6249-6932, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231
Cancers 12
(6): 1454.
3 June 2020
Pro-inflammatory TNF-α and IFN-γ promote tumor growth and metastasis via induction of MACC1.
Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Zhang, C., Clayton-Lucey, I.A., Glauben, R., Voss, C., Siegmund, B. and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Frontiers in Immunology 11
: 980.
27 May 2020
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Koche, R.P. ORCID: https://orcid.org/0000-0002-6820-5083, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Helmsauer, K. ORCID: https://orcid.org/0000-0003-0773-4114, Burkert, M. ORCID: https://orcid.org/0000-0002-6721-9985, MacArthur, I.C., Maag, J., Chamorro, R. ORCID: https://orcid.org/0000-0002-5653-7259, Munoz-Perez, N., Puiggròs, M., Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Röefzaad, C. ORCID: https://orcid.org/0000-0003-2299-6673, Bardinet, V. ORCID: https://orcid.org/0000-0002-9583-7043, Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, Winkler, A., Thole, T., Timme, N., Kasack, K., Fuchs, S. ORCID: https://orcid.org/0000-0001-9619-4329, Klironomos, F. ORCID: https://orcid.org/0000-0003-2627-5662, Thiessen, N., Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Schmelz, K., Künkele, A., Hundsdörfer, P., Rosswog, C., Theissen, J., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Deubzer, H. ORCID: https://orcid.org/0000-0002-6115-4893, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Fischer, M. ORCID: https://orcid.org/0000-0003-1363-1242, Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, Eggert, A., Torrents, D., Schulte, J.H. and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Nature Genetics 52
(1): 29-34.
January 2020
A systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics.
Konrath, F. ORCID: https://orcid.org/0000-0002-6843-6252, Mittermeier, A. ORCID: https://orcid.org/0000-0001-8439-4307, Cristiano, E., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868 and Loewer, A. ORCID: https://orcid.org/0000-0002-8819-3040
PLoS Computational Biology 16
(6): e1007901.
26 June 2020
Deep learning for genomics using Janggu.
Kopp, W. ORCID: https://orcid.org/0000-0003-0376-0032, Monti, R. ORCID: https://orcid.org/0000-0002-6354-8319, Tamburrini, A., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Nature Communications 11
(1): 3488.
13 July 2020
Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Kroschinsky, F., Middeke, J.M., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Lenz, G., Witzens-Harig, M., Bouabdallah, R., La Rosée, P., Viardot, A., Salles, G., Kim, S.J., Kim, T.M., Ottmann, O., Chromik, J., Quinson, A.M., von Wangenheim, U., Burkard, U., Berk, A. and Schmitz, N. ORCID: https://orcid.org/0000-0003-4938-7528
Investigational New Drugs 38
(5): 1472-1482.
October 2020
Murine cytomegalovirus M25 proteins sequester the tumor suppressor protein p53 in nuclear accumulations.
Kutle, I., Szymańska-de Wijs, K.M., Bogdanow, B. ORCID: https://orcid.org/0000-0002-9634-7353, Cuvalo, B., Steinbrück, L., Jonjić, S., Wagner, K., Niedenthal, R., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Wiebusch, L., Dezeljin, M. and Messerle, M.
Journal of Virology 94
(20): e00574-20.
October 2020
Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting.
Lang, K.M. ORCID: https://orcid.org/0000-0001-8855-884X, Harrison, K.L., Williamson, P.R., Huntly, B.J.P., Ossenkoppele, G., Geissler, J., Bereczky, T., Hernández-Rivas, J.M., Chevrou-Séverac, H., Goodbody, R., Schulze-Rath, R. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Trials 21
(1): 437.
27 May 2020
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates.
Langer, H.T. ORCID: https://orcid.org/0000-0003-1838-4279, Afzal, S. ORCID: https://orcid.org/0009-0009-5490-6098, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
Scientific Reports 10
: 1908.
5 February 2020
Targeting the ubiquitin-proteasome system in a pancreatic cancer subtype with hyperactive MYC.
Lankes, K., Hassan, Z.Z., Doffo, M.J., Schneeweis, C., Lier, S., Öllinger, R., Rad, R., Krämer, O.H., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Saur, D., Reichert, M., Schneider, G. and Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872
Molecular Oncology 14
(12): 3048-3064.
December 2020
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.
Lauber, C., Correia, N., Trumpp, A., Rieger, M.A., Dolnik, A., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Roeder, I. and Seifert, M. ORCID: https://orcid.org/0000-0002-2844-053X
Scientific Reports 10
(1): 12761.
29 July 2020
Morphine alleviates pain after heart cryoinjury in zebrafish without impeding regeneration.
Lelek, S., Simões, M. ORCID: https://orcid.org/0000-0002-7340-9128, Hu, B. ORCID: https://orcid.org/0000-0003-0751-885X, Alameldeen, A.M.A., Czajkowski, M.T. ORCID: https://orcid.org/0000-0002-0122-1943, Meyer, A.M. ORCID: https://orcid.org/0000-0002-4665-2077, Ferrara, F., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Panáková, D. ORCID: https://orcid.org/0000-0002-8739-6225
bioRxiv
: 2020.10.01.322560.
2 October 2020
The chloroplast RNA binding protein CP31A has a preference for mRNAs encoding the subunits of the chloroplast NAD(P)H dehydrogenase complex and is required for their accumulation.
Lenzen, B. ORCID: https://orcid.org/0000-0002-7881-9513, Rühle, T., Lehniger, M.K., Okuzaki, A. ORCID: https://orcid.org/0000-0003-1094-5748, Labs, M. ORCID: https://orcid.org/0000-0003-2104-2763, Muino, J.M. ORCID: https://orcid.org/0000-0002-6403-7262, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Leister, D. and Schmitz-Linneweber, C. ORCID: https://orcid.org/0000-0002-6125-4253
International Journal of Molecular Sciences 21
(16): 5633.
6 August 2020
Who with whom: functional coordination of E2 enzymes by RING E3 ligases during poly-ubiquitylation.
Lips, C. ORCID: https://orcid.org/0000-0002-6692-5968, Ritterhoff, T., Weber, A. ORCID: https://orcid.org/0000-0001-8889-5950, Janowska, M.K., Mustroph, M., Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202 and Klevit, R.E. ORCID: https://orcid.org/0000-0002-3476-969X
EMBO Journal 39
(22): e104863.
16 November 2020
Social media big data-based research on the influencing factors of insomnia and spatiotemporal evolution.
Liu, Y. ORCID: https://orcid.org/0000-0003-2151-3668, Luo, Q. ORCID: https://orcid.org/0000-0003-1275-0442, Shen, H. ORCID: https://orcid.org/0000-0002-6434-9055, Zhuang, S. ORCID: https://orcid.org/0000-0001-7320-0247, Xu, C. ORCID: https://orcid.org/0000-0002-7670-0164, Dong, Y. ORCID: https://orcid.org/0000-0002-2390-485X, Sun, Y. ORCID: https://orcid.org/0000-0001-8679-4558, Wang, S. ORCID: https://orcid.org/0000-0002-5437-1718 and Deng, H. ORCID: https://orcid.org/0000-0001-9417-6629
IEEE Access 8
: 41516-41529.
28 February 2020
Getting CD19 into shape: expression of natively folded "difficult-to-express" CD19 for staining and stimulation of CAR-T cells.
Lobner, E., Wachernig, A., Gudipati, V., Mayrhofer, P., Salzer, B., Lehner, M., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Kunert, R.
Frontiers in Bioengineering and Biotechnology 8
: 49.
7 February 2020
Lineage commitment of hematopoietic stem cells and progenitors: insights from recent single cell and lineage tracing technologies.
Loughran, S.J., Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Wilkinson, A.C., Klein, A.M. and Brand, M.
Experimental Hematology 88
: 1-6.
August 2020
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik, P. ORCID: https://orcid.org/0000-0001-9383-8555, Baude, A., Mancarella, D., Öz, S., Kühn, A., Toth, R., Hey, J. ORCID: https://orcid.org/0000-0003-2842-764X, Toprak, U.H., Lim, J. ORCID: https://orcid.org/0000-0001-9358-9552, Nguyen, V.H., Jiang, C., Mayakonda, A., Hartmann, M. ORCID: https://orcid.org/0000-0002-4072-4658, Rosemann, F. ORCID: https://orcid.org/0000-0002-1649-3247, Breuer, K. ORCID: https://orcid.org/0000-0003-3716-7739, Vonficht, D. ORCID: https://orcid.org/0000-0002-5579-7083, Grünschläger, F. ORCID: https://orcid.org/0000-0003-0021-6912, Lee, S., Schuhmacher, M.K., Kusevic, D., Jauch, A., Weichenhan, D., Zustin, J., Schlesner, M. ORCID: https://orcid.org/0000-0002-5896-4086, Haas, S. ORCID: https://orcid.org/0000-0001-9227-2051, Park, J.H., Park, Y.J., Oppermann, U. ORCID: https://orcid.org/0000-0001-9984-5342, Jeltsch, A. ORCID: https://orcid.org/0000-0001-6113-9290, Haller, F. ORCID: https://orcid.org/0000-0002-0148-3273, Fellenberg, J., Lindroth, A.M. ORCID: https://orcid.org/0000-0002-8291-2745 and Plass, C. ORCID: https://orcid.org/0000-0003-2554-3952
Nature Communications 11
(1): 5414.
27 October 2020
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
López, S., Lim, E.L., Horswell, S., Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Huebner, A., Dietzen, M., Mourikis, T.P., Watkins, T.B.K. ORCID: https://orcid.org/0000-0001-7414-737X, Rowan, A., Dewhurst, S.M., Birkbak, N.J. ORCID: https://orcid.org/0000-0003-1613-9587, Wilson, G.A., Van Loo, P. ORCID: https://orcid.org/0000-0003-0292-1949, Jamal-Hanjani, M., Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018 and McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045
Nature Genetics 52
(3): 283-293.
March 2020
Single-cell strand sequencing of a macaque genome reveals multiple nested inversions and breakpoint reuse during primate evolution.
Maggiolini, F.A.M., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Shew, C.J., Sulovari, A., Mao, Y., Puig, M., Catacchio, C.R., Dellino, M., Palmisano, D., Mercuri, L., Bitonto, M., Porubský, D., Cáceres, M., Eichler, E.E., Ventura, M., Dennis, M.Y., Korbel, J.O. and Antonacci, F.
Genome Research 30
(11): 1680-1693.
November 2020
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto, A. ORCID: https://orcid.org/0000-0002-8873-2251, Ohmura, S. ORCID: https://orcid.org/0000-0002-0930-5172, Orth, M.F. ORCID: https://orcid.org/0000-0002-1789-6427, Knott, M.M.L. ORCID: https://orcid.org/0000-0002-6995-3702, Colombo, M.V. ORCID: https://orcid.org/0000-0002-6018-9920, Arrigoni, C. ORCID: https://orcid.org/0000-0001-6808-1642, Bardinet, V. ORCID: https://orcid.org/0000-0002-9583-7043, Saucier, D. ORCID: https://orcid.org/0000-0001-8484-198X, Wehweck, F.S., Li, J., Stein, S., Gerke, J.S., Baldauf, M.C., Musa, J. ORCID: https://orcid.org/0000-0002-9138-1819, Dallmayer, M., Romero-Pérez, L. ORCID: https://orcid.org/0000-0003-3196-4382, Hölting, T.L.B. ORCID: https://orcid.org/0000-0001-5598-7330, Amatruda, J.F. ORCID: https://orcid.org/0000-0002-9901-2137, Cossarizza, A. ORCID: https://orcid.org/0000-0002-5381-1558, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Kirchner, T., Moretti, M., Cidre-Aranaz, F. ORCID: https://orcid.org/0000-0002-0246-7179, Sannino, G. and Grünewald, T.G.P. ORCID: https://orcid.org/0000-0003-0920-7377
Nature Communications 11
(1): 2423.
15 May 2020
AP-1 imprints a reversible transcriptional programme of senescent cells.
Martínez-Zamudio, R.I. ORCID: https://orcid.org/0000-0001-9202-4285, Roux, P.F., de Freitas, J.A.N.L.F. ORCID: https://orcid.org/0000-0003-3689-765X, Robinson, L., Doré, G., Sun, B. ORCID: https://orcid.org/0000-0002-8963-4100, Belenki, D. ORCID: https://orcid.org/0000-0002-9004-9849, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Herbig, U., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Gil, J. ORCID: https://orcid.org/0000-0002-4303-6260 and Bischof, O. ORCID: https://orcid.org/0000-0003-2422-6277
Nature Cell Biology 22
(7): 842-855.
July 2020
EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C. ORCID: https://orcid.org/0000-0003-3242-1195, Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Jonas, W., Melo, A.A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Blüher, M., Olschowski, H., Kompa, J., Brügger, B., Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993, Schürmann, A. ORCID: https://orcid.org/0000-0002-4113-4377, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Proceedings of the National Academy of Sciences of the United States of America 117
(13): 7471-7481.
31 March 2020
Angiogenesis in lymph nodes is a critical regulator of immune response and lymphoma growth.
Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Frontiers in Immunology 11
: 591741.
3 December 2020
Peptide-based interaction proteomics.
Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Molecular & Cellular Proteomics 19
(7): 1070-1075.
July 2020
Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1).
Meyer, T., Jahn, N., Lindner, S., Röhner, L., Dolnik, A., Weber, D., Scheffold, A., Köpff, S., Paschka, P., Gaidzik, V.I., Heckl, D., Wiese, S., Ebert, B.L., Döhner, H., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, K. and Krönke, J.
Leukemia 34
(2): 404-415.
February 2020
Deficiency in IκBα in the intestinal epithelium leads to spontaneous inflammation and mediates apoptosis in the gut.
Mikuda, N., Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Kärgel, E., Golusda, L., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Kühl, A.A. and Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061
Journal of Pathology 251
(2): 160-174.
June 2020
ABVD vs BEACOPP escalated in advanced-stage Hodgkin's lymphoma: Results from a multicenter European study.
Mondello, P. ORCID: https://orcid.org/0000-0002-0355-3757, Musolino, C., Dogliotti, I., Bohn, J.P. ORCID: https://orcid.org/0000-0002-2066-7377, Cavallo, F., Ferrero, S., Botto, B., Cerchione, C., Nappi, D., De Lorenzo, S., Martinelli, G., Wolf, D., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Loseto, G., Cuzzocrea, S., Willenbacher, W., Mian, M. ORCID: https://orcid.org/0000-0003-2539-5996 and Straus, D.J.
American Journal of Hematology 95
(9): 1030-1037.
September 2020
Accelerating drug development for neuroblastoma: summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma.
Moreno, L. ORCID: https://orcid.org/0000-0002-0708-1670, Barone, G., DuBois, S.G., Molenaar, J., Fischer, M., Schulte, J., Eggert, A., Schleiermacher, G., Speleman, F., Chesler, L., Geoerger, B., Hogarty, M.D., Irwin, M.S., Bird, N., Blanchard, G.B., Buckland, S., Caron, H., Davis, S., De Wilde, B., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Dolman, E., Eilers, M., George, R.E., George, S., Jaroslav, Š., Maris, J.M., Marshall, L., Merchant, M., Mortimer, P., Owens, C., Philpott, A., Poon, E., Shay, J.W., Tonelli, R. ORCID: https://orcid.org/0000-0002-7222-7824, Valteau-Couanet, D., Vassal, G., Park, J.R. and Pearson, A.D.J.
European Journal of Cancer 136
: 52-68.
September 2020
From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement.
Mostinski, Y., Heynen, G.J.J.E. ORCID: https://orcid.org/0000-0001-7721-5710, López-Alberca, M.P., Paul, J., Miksche, S., Radetzki, S. ORCID: https://orcid.org/0000-0003-2688-2868, Schaller, D., Shanina, E., Seyffarth, C., Kolomeets, Y., Ziebart, N., de Schryver, J., Oestreich, S., Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Rademacher, C., Volkamer, A. ORCID: https://orcid.org/0000-0002-3760-580X, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Nazaré, M. ORCID: https://orcid.org/0000-0002-1602-2330
Journal of Medicinal Chemistry 63
(23): 14780-14804.
10 December 2020
A quantitative modular modeling approach reveals the effects of different A20 feedback implementations for the NF-κB signaling dynamics.
Mothes, J. ORCID: https://orcid.org/0000-0001-8679-0688, Ipenberg, I. ORCID: https://orcid.org/0009-0007-6788-5009, Arslan, S.Ç., Benary, U. ORCID: https://orcid.org/0000-0001-7801-8639, Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
Frontiers in Physiology 11
: 896.
28 July 2020
Single-cell analysis based dissection of clonality in myelofibrosis.
Mylonas, E. ORCID: https://orcid.org/0000-0001-6831-969X, Yoshida, K. ORCID: https://orcid.org/0000-0003-4612-2778, Frick, M., Hoyer, K., Christen, F., Kaeda, J., Obenaus, M., Noerenberg, D., Hennch, C. ORCID: https://orcid.org/0000-0003-4104-5531, Chan, W., Ochi, Y., Shiraishi, Y., Shiozawa, Y., Zenz, T., Oakes, C.C., Sawitzki, B., Schwarz, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, le Coutre, P., Rose-Zerilli, M.J.J., Ogawa, S. and Damm, F.
Nature Communications 11
(1): 73.
7 January 2020
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Müller, P.M. ORCID: https://orcid.org/0000-0001-9056-4114, Rademacher, J., Bagshaw, R.D. ORCID: https://orcid.org/0000-0001-5013-4291, Wortmann, C., Barth, C., van Unen, J., Alp, K.M. ORCID: https://orcid.org/0000-0001-9919-9838, Giudice, G., Eccles, R.L. ORCID: https://orcid.org/0000-0002-8209-5650, Heinrich, L.E., Pascual-Vargas, P., Sanchez-Castro, M., Brandenburg, L., Mbamalu, G., Tucholska, M., Spatt, L., Czajkowski, M.T. ORCID: https://orcid.org/0000-0002-0122-1943, Welke, R.W., Zhang, S., Nguyen, V., Rrustemi, T. ORCID: https://orcid.org/0000-0002-9075-103X, Trnka, P., Freitag, K. ORCID: https://orcid.org/0000-0002-5244-3140, Larsen, B., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Gingras, A.C. ORCID: https://orcid.org/0000-0002-6090-4437, Roth, F.P. ORCID: https://orcid.org/0000-0002-6628-649X, Colwill, K. ORCID: https://orcid.org/0000-0002-8979-1659, Bakal, C. ORCID: https://orcid.org/0000-0002-0413-6744, Pertz, O. ORCID: https://orcid.org/0000-0001-8579-4919, Pawson, T., Petsalaki, E. ORCID: https://orcid.org/0000-0002-8294-2995 and Rocks, O. ORCID: https://orcid.org/0000-0001-6349-9193
Nature Cell Biology 22
(4): 498-511.
April 2020
Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications.
Oevermann, L., Zimmermann, C. ORCID: https://orcid.org/0000-0003-2956-1410, Voigt, S. ORCID: https://orcid.org/0000-0003-1544-9903, Künkele, A., Lobitz, S. ORCID: https://orcid.org/0000-0001-5398-0610, Eggert, A., Schulte, J.H., Kaufer, B.B. and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Bone Marrow Transplantation 55
(1): 260-264.
January 2020
Inclusion of temporal information in single cell transcriptomics.
Olivares-Chauvet, P. and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
International Journal of Biochemistry and Cell Biology 122
: 105745.
May 2020
Towards a more reliable identification of isomeric metabolites using pattern guided retention validation.
Opialla, T. ORCID: https://orcid.org/0000-0001-9527-8061, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Pietzke, M. ORCID: https://orcid.org/0000-0002-6901-8511
Metabolites 10
(11): 457.
12 November 2020
High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma.
Orth, M.F. ORCID: https://orcid.org/0000-0002-1789-6427, Hölting, T.L.B., Dallmayer, M., Wehweck, F.S., Paul, T., Musa, J. ORCID: https://orcid.org/0000-0002-9138-1819, Baldauf, M.C., Surdez, D. ORCID: https://orcid.org/0000-0002-7118-7859, Delattre, O., Knott, M.M.L. ORCID: https://orcid.org/0000-0002-6995-3702, Romero-Pérez, L. ORCID: https://orcid.org/0000-0003-3196-4382, Kasan, M. ORCID: https://orcid.org/0000-0002-9031-2109, Cidre-Aranaz, F. ORCID: https://orcid.org/0000-0002-0246-7179, Gerke, J.S., Ohmura, S. ORCID: https://orcid.org/0000-0002-0930-5172, Li, J., Marchetto, A., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Özen, Ö., Sugita, S., Hasegawa, T., Kanaseki, T., Bertram, S., Dirksen, U. ORCID: https://orcid.org/0000-0002-5435-7860, Hartmann, W., Kirchner, T. and Grünewald, T.G.P. ORCID: https://orcid.org/0000-0003-0920-7377
Cancers 12
(3): 644.
10 March 2020
Multiplexed quantification of four neuroblastoma DNA targets in a single droplet digital PCR reaction.
Peitz, C., Sprüssel, A., Linke, R.B., Astrahantseff, K. ORCID: https://orcid.org/0000-0002-7872-1997, Grimaldi, M., Schmelz, K., Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Schulte, J.H., Fischer, M., Messerschmidt, C. ORCID: https://orcid.org/0000-0001-8632-656X, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Keilholz, U., Eggert, A., Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893 and Lodrini, M.
Journal of Molecular Diagnostics 22
(11): 1309-1323.
November 2020
Targeting claudin-overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin.
Piontek, A., Eichner, M., Zwanziger, D., Beier, L.S., Protze, J., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Theurer, S., Schmid, K.W., Führer-Sakel, D., Piontek, J. and Krause, G.
Molecular Oncology 14
(2): 261-276.
February 2020
Unscrambling fluorophore blinking for comprehensive cluster detection via photoactivated localization microscopy.
Platzer, R., Rossboth, B.K., Schneider, M.C. ORCID: https://orcid.org/0000-0002-3771-8353, Sevcsik, E., Baumgart, F., Stockinger, H. ORCID: https://orcid.org/0000-0001-6404-4430, Schütz, G.J. ORCID: https://orcid.org/0000-0003-1542-1089, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198 and Brameshuber, M. ORCID: https://orcid.org/0000-0001-8672-2255
Nature Communications 11
(1): 4993.
5 October 2020
Using gradient boosting with stability selection on health insurance claims data to identify disease trajectories in chronic obstructive pulmonary disease.
Ploner, T. ORCID: https://orcid.org/0000-0003-0800-5722, Heß, S., Grum, M., Drewe-Boss, P. ORCID: https://orcid.org/0000-0002-5459-9771 and Walker, J.
Statistical Methods in Medical Research 29
(12): 3684-3694.
1 December 2020
Recurrent inversion toggling and great ape genome evolution.
Porubsky, D., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Höps, W., Hsieh, P. ORCID: https://orcid.org/0000-0001-8294-6227, Sulovari, A. ORCID: https://orcid.org/0000-0003-4354-9020, Li, R., Mercuri, L., Sorensen, M., Murali, S.C., Gordon, D., Cantsilieris, S., Pollen, A.A., Ventura, M. ORCID: https://orcid.org/0000-0001-7762-8777, Antonacci, F. ORCID: https://orcid.org/0000-0002-5833-6186, Marschall, T. ORCID: https://orcid.org/0000-0002-9376-1030, Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794 and Eichler, E.E. ORCID: https://orcid.org/0000-0002-8246-4014
Nature Genetics 52
(8): 849-858.
August 2020
breakpointR: an R/Bioconductor package to localize strand state changes in Strand-seq data.
Porubsky, D., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Taudt, A. ORCID: https://orcid.org/0000-0002-9639-2306, Colomé-Tatché, M., Lansdorp, P.M. and Guryev, V.
Bioinformatics 36
(4): 1260-1261.
15 February 2020
First-line treatment with R-CHOP or rituximab-bendamustine in patients with follicular lymphoma grade 3A - results of a retrospective analysis.
Pouyiourou, M., Meyer, A., Stroux, A., Viardot, A., La Rosée, P., Maschmeyer, G., Kämpfe, D., Kahl, C., Vucinic, V., Monecke, A., Hirt, C., Weber, T., Meissner, J., Witzens-Harig, M., Böttcher, S., Schmalenberg, H., Marks, R., Prange-Krex, G., Kroschinsky, F., Hauf, E., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Koch, K., Klapper, W., Herold, M. and Scholz, C.W. ORCID: https://orcid.org/0000-0001-6260-4086
Annals of Hematology 99
(12): 2821-2829.
December 2020
Tracing tumorigenesis in a solid tumor model at single-cell resolution.
Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271, Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Zhu, Q., Fang, L., Liu, H. ORCID: https://orcid.org/0009-0007-4871-452X, Quinn, H. ORCID: https://orcid.org/0000-0002-1336-5709, Stoeckius, M. ORCID: https://orcid.org/0000-0002-5658-029X, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Nature Communications 11
(1): 991.
20 February 2020
Better prognosis of gastric cancer patients with high levels of tumor infiltrating lymphocytes is counteracted by PD-1 expression.
Pötzsch, M., Berg, E., Hummel, M., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X, von Winterfeld, M., Jöhrens, K., Rau, B., Daum, S. and Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773
OncoImmunology 9
(1): 1824632.
30 September 2020
Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells.
Raffel, S. ORCID: https://orcid.org/0000-0003-4671-1097, Klimmeck, D., Falcone, M. ORCID: https://orcid.org/0000-0003-0906-5735, Demir, A. ORCID: https://orcid.org/0000-0001-7327-7682, Pouya, A. ORCID: https://orcid.org/0000-0002-9458-1648, Zeisberger, P., Lutz, C., Tinelli, M., Bischel, O., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Thiede, C., Flörcken, A., Westermann, J., Ehninger, G., Ho, A.D., Müller-Tidow, C. ORCID: https://orcid.org/0000-0002-7166-5232, Gu, Z., Herrmann, C. ORCID: https://orcid.org/0000-0003-4989-4722, Krijgsveld, J. ORCID: https://orcid.org/0000-0001-7549-9326, Trumpp, A. ORCID: https://orcid.org/0000-0002-6212-3466 and Hansson, J. ORCID: https://orcid.org/0000-0001-9174-8089
Blood 136
(13): 1507-1519.
24 September 2020
Safety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part phase Ib/II study.
Rambaldi, A. ORCID: https://orcid.org/0000-0002-3739-7502, Iurlo, A. ORCID: https://orcid.org/0000-0002-4401-0812, Vannucchi, A.M., Noble, R., von Bubnoff, N., Guarini, A., Martino, B., Pezzutto, A. ORCID: https://orcid.org/0000-0002-3246-4470, Carli, G., De Muro, M., Luciani, S., McMullin, M.F. ORCID: https://orcid.org/0000-0002-0773-0204, Cambier, N., Marolleau, J.P., Mesa, R.A., Tibes, R., Pancrazzi, A., Gesullo, F., Bettica, P., Manzoni, S. and Di Tollo, S.
Leukemia 34
(8): 2234-2237.
August 2020
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features.
Ray, J.P., de Boer, C.G., Fulco, C.P. ORCID: https://orcid.org/0000-0002-6592-1279, Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Kanai, M. ORCID: https://orcid.org/0000-0001-5165-4408, Ulirsch, J.C. ORCID: https://orcid.org/0000-0002-7947-0827, Tewhey, R. ORCID: https://orcid.org/0000-0002-4607-8001, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Reilly, S.K., Bergman, D.T. ORCID: https://orcid.org/0000-0002-8314-7088, Engreitz, J.M. ORCID: https://orcid.org/0000-0002-5754-1719, Issner, R., Finucane, H.K. ORCID: https://orcid.org/0000-0003-3864-9828, Lander, E.S. ORCID: https://orcid.org/0000-0003-2662-4631, Regev, A. ORCID: https://orcid.org/0000-0003-3293-3158 and Hacohen, N. ORCID: https://orcid.org/0000-0002-2349-2656
Nature Communications 11
(1): 1237.
6 March 2020
The mole genome reveals regulatory rearrangements associated with adaptive intersexuality.
Real, F.M. ORCID: https://orcid.org/0000-0003-0692-2260, Haas, S.A. ORCID: https://orcid.org/0000-0003-3418-3688, Franchini, P. ORCID: https://orcid.org/0000-0002-8184-1463, Xiong, P. ORCID: https://orcid.org/0000-0002-8346-9132, Simakov, O. ORCID: https://orcid.org/0000-0002-3585-4511, Kuhl, H. ORCID: https://orcid.org/0000-0001-7623-9227, Schöpflin, R., Heller, D. ORCID: https://orcid.org/0000-0001-8346-9565, Moeinzadeh, M.H. ORCID: https://orcid.org/0000-0002-6787-3047, Heinrich, V. ORCID: https://orcid.org/0000-0001-9775-3276, Krannich, T. ORCID: https://orcid.org/0000-0002-5525-1849, Bressin, A. ORCID: https://orcid.org/0000-0002-3170-4823, Hartmann, M.F. ORCID: https://orcid.org/0000-0001-7232-9532, Wudy, S.A. ORCID: https://orcid.org/0000-0002-7163-5957, Dechmann, D.K.N. ORCID: https://orcid.org/0000-0003-0043-8267, Hurtado, A. ORCID: https://orcid.org/0000-0001-6267-704X, Barrionuevo, F.J. ORCID: https://orcid.org/0000-0003-2651-1530, Schindler, M. ORCID: https://orcid.org/0000-0003-3363-1864, Harabula, I. ORCID: https://orcid.org/0000-0002-9094-0519, Osterwalder, M. ORCID: https://orcid.org/0000-0002-1969-2313, Hiller, M. ORCID: https://orcid.org/0000-0003-3024-1449, Wittler, L., Visel, A. ORCID: https://orcid.org/0000-0002-4130-7784, Timmermann, B., Meyer, A. ORCID: https://orcid.org/0000-0002-0888-8193, Vingron, M. ORCID: https://orcid.org/0000-0002-1765-4241, Jiménez, R., Mundlos, S. ORCID: https://orcid.org/0000-0002-9788-3166 and Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X
Science 370
(6513): 208-214.
9 October 2020
Lineage-resolved enhancer and promoter usage during a time course of embryogenesis.
Reddington, J.P., Garfield, D.A. ORCID: https://orcid.org/0000-0002-8790-797X, Sigalova, O.M., Karabacak Calviello, A. ORCID: https://orcid.org/0000-0002-4740-7938, Marco-Ferreres, R., Girardot, C., Viales, R.R., Degner, J.F., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Furlong, E.E.M.
Developmental Cell 55
(5): 648-664.
7 December 2020
Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1.
Reinke, S., Bröckelmann, P.J., Iaccarino, I., Garcia-Marquez, M., Borchmann, S., Jochims, F., Kotrova, M., Pal, K., Brüggemann, M., Hartmann, E., Sasse, S., Kobe, C., Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Soekler, M., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bormann, M., Zimmermann, A., Richter, J., Fuchs, M., von Tresckow, B., Borchmann, P., Schlößer, H., von Bergwelt-Baildon, M., Rosenwald, A., Engert, A. and Klapper, W.
Blood 136
(25): 2851-2863.
17 December 2020
A CD205-directed antibody drug conjugate - lymphoma precision oncology or sophisticated chemotherapy?
Rieke, D.T. and Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958
Haematologica 105
(11): 2504-2506.
1 November 2020
Instability of circular RNAs in clinical tissue samples impairs their reliable expression analysis using RT-qPCR: from the myth of their advantage as biomarkers to reality.
Rochow, H., Franz, A., Jung, M., Weickmann, S., Ralla, B., Kilic, E., Stephan, C., Fendler, A. ORCID: https://orcid.org/0000-0002-7267-0981 and Jung, K.
Theranostics 10
(20): 9268-9279.
23 July 2020
Circular RNAs and their linear transcripts as diagnostic and prognostic tissue biomarkers in prostate cancer after prostatectomy in combination with clinicopathological factors.
Rochow, H., Jung, M., Weickmann, S., Ralla, B., Stephan, C., Elezkurtaj, S., Kilic, E., Zhao, Z., Jung, K., Fendler, A. ORCID: https://orcid.org/0000-0002-7267-0981 and Franz, A.
International Journal of Molecular Sciences 21
(21): E7812.
22 October 2020
Quantification of mRNA expression using single-molecule nanopore sensing.
Rozevsky, Y., Gilboa, T., van Kooten, X.F. ORCID: https://orcid.org/0000-0003-2411-6174, Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Huttner, D., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Meller, A. ORCID: https://orcid.org/0000-0001-7082-0985
ACS Nano 14
(10): 13964-13974.
27 October 2020
Mapping the transglycosylation relevant sites of cold-adapted β-d-galactosidase from arthrobacter sp. 32cB.
Rutkiewicz, M. ORCID: https://orcid.org/0000-0001-8339-3230, Wanarska, M. and Bujacz, A. ORCID: https://orcid.org/0000-0002-0808-1349
International Journal of Molecular Sciences 21
(15): 5354.
28 July 2020
Editorial: Modulation of human immune parameters by anticancer therapies.
Sack, U., Tarnok, A., Preijers, F., Köhl, U. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
Frontiers in Immunology 11
: 621556.
2 December 2020
Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function.
Salzer, B. ORCID: https://orcid.org/0000-0003-4282-6356, Schueller, C.M. ORCID: https://orcid.org/0000-0001-7618-6815, Zajc, C.U. ORCID: https://orcid.org/0000-0002-9356-7430, Peters, T., Schoeber, M.A. ORCID: https://orcid.org/0000-0003-4918-5061, Kovacic, B. ORCID: https://orcid.org/0000-0001-7261-0201, Buri, M.C., Lobner, E. ORCID: https://orcid.org/0000-0002-5234-5524, Dushek, O. ORCID: https://orcid.org/0000-0001-5847-5226, Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Obinger, C. ORCID: https://orcid.org/0000-0002-7133-3430, Putz, E.M. ORCID: https://orcid.org/0000-0002-9990-4477, Holter, W., Traxlmayr, M.W. ORCID: https://orcid.org/0000-0002-2108-582X and Lehner, M. ORCID: https://orcid.org/0000-0002-5776-4218
Nature Communications 11
(1): 4166.
20 August 2020
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity.
Salzer, E., Zoghi, S., Kiss, M.G., Kage, F., Rashkova, C., Stahnke, S., Haimel, M., Platzer, R., Caldera, M., Ardy, R.C., Hoeger, B., Block, J., Medgyesi, D., Sin, C., Shahkarami, S., Kain, R., Ziaee, V., Hammerl, P., Bock, C., Menche, J., Dupré, L., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Sixt, M., Lomakin, A., Rottner, K., Binder, C.J., Stradal, T.E.B., Rezaei, N. and Boztug, K.
Science Immunology 5
(49): eabc3979.
10 July 2020
Subnanometer-resolution structure determination in situ by hybrid subtomogram averaging - single particle cryo-EM.
Sanchez, R.M., Zhang, Y. ORCID: https://orcid.org/0000-0002-6478-476X, Chen, W., Dietrich, L. and Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274
Nature Communications 11
(1): 3709.
24 July 2020
Single-cell analysis of structural variations and complex rearrangements with tri-channel processing.
Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Meiers, S., Ghareghani, M., Porubsky, D., Jeong, H., van Vliet, M.A.C.C., Rausch, T. ORCID: https://orcid.org/0000-0001-5773-5620, Richter-Pechańska, P. ORCID: https://orcid.org/0000-0001-6727-6317, Kunz, J.B., Jenni, S., Bolognini, D. ORCID: https://orcid.org/0000-0002-8735-8093, Longo, G.M.C., Raeder, B. ORCID: https://orcid.org/0000-0002-9494-8884, Kinanen, V., Zimmermann, J., Benes, V. ORCID: https://orcid.org/0000-0002-0352-2547, Schrappe, M., Mardin, B.R. ORCID: https://orcid.org/0000-0002-3903-9354, Kulozik, A.E., Bornhauser, B., Bourquin, J.P., Marschall, T. ORCID: https://orcid.org/0000-0002-9376-1030 and Korbel, J.O. ORCID: https://orcid.org/0000-0002-2798-3794
Nature Biotechnology 38
(3): 343-354.
March 2020
Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS).
Scheer, M. ORCID: https://orcid.org/0000-0002-0665-6268, Blank, B., Bauer, S., Vokuhl, C., Stegmaier, S., Feuchtgruber, S., Henssen, A. ORCID: https://orcid.org/0000-0003-1534-778X, Sparber-Sauer, M., Eggert, A., Handgretinger, R., Pekrun, A., Rossig, C., Rutkowski, S., Schlegel, P.G., Schrappe, M., Simon, T., Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Jahnukainen, K., Fuchs, J., Bielack, S.S., Koscielniak, E. and Klingebiel, T.
Journal of Cancer Research and Clinical Oncology 146
(4): 953-960.
April 2020
H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.
Schleich, K., Kase, J., Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Trescher, S., Bhattacharya, A. ORCID: https://orcid.org/0000-0003-3733-7670, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Wailes, E.M., Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Lohneis, P., Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Lau, A., Lenze, D., Hummel, M., Chapuy, B., Leser, U., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Communications 11
(1): 3651.
20 July 2020
B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS.
Schmidt, K., Sack, U., Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Frontiers in Immunology 11
: 602868.
1 December 2020
ASH highlights 2019: "aggressive B-cell lymphoma".
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
memo: Magazine of European Medical Oncology 13
(3): 266-269.
20 May 2020
The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Scholz, F. ORCID: https://orcid.org/0000-0002-0253-081X, Grau, M., Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Graband, A. ORCID: https://orcid.org/0000-0002-9038-0734, Zapukhlyak, M. ORCID: https://orcid.org/0000-0002-2635-6940, Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Lenz, G., Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950 and Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893
Proceedings of the National Academy of Sciences of the United States of America 117
(42): 26328-26339.
20 October 2020
Severe COVID-19 is marked by a dysregulated myeloid cell compartment.
Schulte-Schrepping, J., Reusch, N., Paclik, D., Baßler, K., Schlickeiser, S., Zhang, B., Krämer, B., Krammer, T., Brumhard, S., Bonaguro, L., De Domenico, E., Wendisch, Da., Grasshoff, M., Kapellos, T.S., Beckstette, M., Pecht, T., Saglam, A., Dietrich, O., Mei, H.E., Schulz, A.R., Conrad, C., Kunkel, D., Vafadarnejad, E., Xu, C.J., Horne, A. ORCID: https://orcid.org/0000-0002-4209-4573, Herbert, M., Drews, A., Thibeault, C., Pfeiffer, M., Hippenstiel, S., Hocke, A., Müller-Redetzky, H., Heim, K.M., Machleidt, F., Uhrig, A., Bosquillon de Jarcy, L., Jürgens, L., Stegemann, M., Glösenkamp, C.R., Volk, H.D., Goffinet, C., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Georg, P., Schneider, M., Dang-Heine, C., Neuwinger, N., Kappert, K., Tauber, R., Corman, V., Raabe, J., Kaiser, K.M., Vinh, M.T., Rieke, G., Meisel, C., Ulas, T., Becker, M., Geffers, R., Witzenrath, M., Drosten, C., Suttorp, N., von Kalle, C., Kurth, F., Händler, K., Schultze, J.L., Aschenbrenner, A.C., Li, Y., Nattermann, J., Sawitzki, B., Saliba, A.E. and Sander, L.E.
Cell 182
(6): 1419-1440.
17 September 2020
The transcriptome dynamics of single cells during the cell cycle.
Schwabe, D. ORCID: https://orcid.org/0000-0003-2825-3352, Formichetti, S. ORCID: https://orcid.org/0000-0002-7907-2239, Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290, Falcke, M. ORCID: https://orcid.org/0000-0001-7137-1114 and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Molecular Systems Biology 16
(11): e9946.
1 November 2020
Spatio-temporal bone remodeling after hematopoietic stem cell transplantation.
Schwarz, C.S., Bucher, C.H. ORCID: https://orcid.org/0000-0002-3900-088X, Schlundt, C., Mertlitz, S., Riesner, K., Kalupa, M., Verlaat, L., Schmidt-Bleek, O., Sass, R.A., Schmidt-Bleek, K. ORCID: https://orcid.org/0000-0002-5719-0867, Duda, G.N., Penack, O. and Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424
International Journal of Molecular Sciences 22
(1): 267.
29 December 2020
The effects of common structural variants on 3D chromatin structure.
Shanta, O., Noor, A. and Sebat, J. ORCID: https://orcid.org/0000-0002-9087-526X
BMC Genomics 21
(1): 95.
30 January 2020
The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay.
Silla, T., Schmid, M., Dou, Y., Garland, W., Milek, M. ORCID: https://orcid.org/0000-0002-0803-8439, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Johnsen, D., Polak, P., Andersen, J.S., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Jensen, T. ORCID: https://orcid.org/0000-0001-5127-1239
Nucleic Acids Research 48
(5): 2518-2530.
18 March 2020
Bacteriophages: emerging applications in medicine, food, and biotechnology.
Sohail, H.A., Coffey, A., Debrowska, K., Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479, Middelboe, M., Sohail, M. and Clokie, M.R.J.
PHAGE 1
(2): 75-82.
16 June 2020
Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
Sommermann, T. ORCID: https://orcid.org/0000-0003-2899-0256, Yasuda, T. ORCID: https://orcid.org/0000-0001-9997-6852, Ronen, J. ORCID: https://orcid.org/0000-0003-3980-6469, Wirtz, T. ORCID: https://orcid.org/0009-0005-5677-9804, Weber, T. ORCID: https://orcid.org/0000-0003-2079-842X, Sack, U., Caeser, R., Zhang, J., Li, X. ORCID: https://orcid.org/0000-0002-1173-1066, Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696, Jauch, A., Unger, K., Hodson, D.J. ORCID: https://orcid.org/0000-0001-6225-2033, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370
Proceedings of the National Academy of Sciences of the United States of America 117
(25): 14421-14432.
23 June 2020
Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing.
Stangl, C., de Blank, S. ORCID: https://orcid.org/0000-0003-2191-5675, Renkens, I., Westera, L., Verbeek, T., Valle-Inclan, J.E., Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, van Roosmalen, M.J., Stam, R.W., Voest, E.E. ORCID: https://orcid.org/0000-0001-8249-9586, Kloosterman, W.P. ORCID: https://orcid.org/0000-0003-3357-4580, van Haaften, G. ORCID: https://orcid.org/0000-0003-3033-0329 and Monroe, G.R. ORCID: https://orcid.org/0000-0002-8653-2643
Nature Communications 11
(1): 2861.
5 June 2020
HCoV- and SARS-CoV-2 cross-reactive T cells in CVID patients.
Steiner, S., Sotzny, F., Bauer, S., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Schmueck-Henneresse, M., Corman, V.M., Schwarz, T., Drosten, C., Wendering, D.J., Behrends, U., Volk, H.D., Scheibenbogen, C. and Hanitsch, L.G.
Frontiers in Immunology 11
: 607918.
23 December 2020
Combination therapy with Olaratumab/doxorubicin in advanced or metastatic soft tissue sarcoma -a single-Centre experience.
Striefler, J.K. ORCID: https://orcid.org/0000-0002-0612-3023, Brandes, F., Baur, A., Pfitzner, B.M., Kaul, D., Rau, D., Dörr, A., Schmiester, M., Koulaxouzidis, G., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Märdian, S. and Flörcken, A.
BMC Cancer 20
(1): 68.
29 January 2020
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
Swan, A.L. ORCID: https://orcid.org/0000-0003-1810-3756, Schütt, C., Rozman, J. ORCID: https://orcid.org/0000-0002-8035-8904, Del Mar Muñiz Moreno, M. ORCID: https://orcid.org/0000-0002-2662-890X, Brandmaier, S., Simon, M., Leuchtenberger, S. ORCID: https://orcid.org/0000-0003-2475-0810, Griffiths, M., Brommage, R. ORCID: https://orcid.org/0000-0002-9947-3822, Keskivali-Bond, P., Grallert, H. ORCID: https://orcid.org/0000-0002-6876-9655, Werner, T. ORCID: https://orcid.org/0000-0003-0402-4539, Teperino, R. ORCID: https://orcid.org/0000-0001-8815-1409, Becker, L. ORCID: https://orcid.org/0000-0002-6890-4984, Miller, G. ORCID: https://orcid.org/0000-0002-4281-4905, Moshiri, A., Seavitt, J.R. ORCID: https://orcid.org/0000-0003-3209-3187, Cissell, D.D. ORCID: https://orcid.org/0000-0002-6450-422X, Meehan, T.F., Acar, E.F. ORCID: https://orcid.org/0000-0003-2908-7691, Lelliott, C.J. ORCID: https://orcid.org/0000-0001-8087-4530, Flenniken, A.M., Champy, M.F., Sorg, T., Ayadi, A., Braun, R.E. ORCID: https://orcid.org/0000-0003-3856-9465, Cater, H. ORCID: https://orcid.org/0000-0002-8696-6070, Dickinson, M.E., Flicek, P. ORCID: https://orcid.org/0000-0002-3897-7955, Gallegos, J., Ghirardello, E.J. ORCID: https://orcid.org/0000-0002-1100-9217, Heaney, J.D. ORCID: https://orcid.org/0000-0001-8475-8828, Jacquot, S., Lally, C. ORCID: https://orcid.org/0000-0002-3801-1966, Logan, J.G. ORCID: https://orcid.org/0000-0003-2801-700X, Teboul, L., Mason, J. ORCID: https://orcid.org/0000-0002-2796-5123, Spielmann, N., McKerlie, C., Murray, S.A., Nutter, L.M.J. ORCID: https://orcid.org/0000-0001-9619-146X, Odfalk, K.F. ORCID: https://orcid.org/0000-0003-4152-4583, Parkinson, H., Prochazka, J. ORCID: https://orcid.org/0000-0003-4675-8995, Reynolds, C.L., Selloum, M. ORCID: https://orcid.org/0000-0003-4057-3519, Spoutil, F. ORCID: https://orcid.org/0000-0002-7310-3487, Svenson, K.L. ORCID: https://orcid.org/0000-0002-7928-1911, Vales, T.S. ORCID: https://orcid.org/0000-0001-9751-5681, Wells, S.E. ORCID: https://orcid.org/0000-0002-0572-0600, White, J.K. ORCID: https://orcid.org/0000-0001-6268-2826, Sedlacek, R. ORCID: https://orcid.org/0000-0002-3352-392X, Wurst, W. ORCID: https://orcid.org/0000-0003-4422-7410, Lloyd, K.K.C. ORCID: https://orcid.org/0000-0002-5318-4144, Croucher, P.I., Fuchs, H., Williams, G.R. ORCID: https://orcid.org/0000-0002-8555-8219, Bassett, D., Gailus-Durner, V., Herault, Y. ORCID: https://orcid.org/0000-0001-7049-6900, Mallon, A.M., Brown, S.D.M. ORCID: https://orcid.org/0000-0002-0617-4824, Mayer-Kuckuk, P. and Hrabe de Angelis, M. ORCID: https://orcid.org/0000-0002-7898-2353
PLoS Genetics 16
(12): e1009190.
28 December 2020
Towards a deeper annotation of human lncRNAs.
Szcześniak, M.W., Wanowska, E., Mukherjee, N. ORCID: https://orcid.org/0000-0003-0017-1400, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116 and Makałowska, I.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1863
(4): 194385.
April 2020
Keeping the proportions of protein complex components in check.
Taggart, J.C., Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Li, G.W. and McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063
Cell Systems 10
(2): 125-132.
26 February 2020
Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.
Tausch, E., Beck, P., Schlenk, R.F., Jebaraj, B.M.C., Dolnik, A., Yosifov, D.Y., Hillmen, P., Offner, F., Janssens, A., Babu, K.G., Grosicki, S., Mayer, J., Panagiotidis, P., McKeown, A., Gupta, I.V., Skorupa, A., Pallaud, C., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertens, D., Döhner, H. and Stilgenbauer, S.
Haematologica 105
(10): 2440-2447.
October 2020
Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.
Tausch, E., Schneider, C., Robrecht, S., Zhang, C., Dolnik, A., Bloehdorn, J., Bahlo, J., Al-Sawaf, O., Ritgen, M., Fink, A.M., Eichhorst, B., Kreuzer, K.A., Tandon, M., Humphrey, K., Jiang, Y., Schary, W., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mertens, D., Lurà, M.P., Kneba, M., Döhner, H., Fischer, K., Hallek, M. and Stilgenbauer, S.
Blood 135
(26): 2402-2412.
25 June 2020
ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope.
Textoris-Taube, K., Cammann, C., Henklein, P., Topfstedt, E., Ebstein, F., Henze, S., Liepe, J., Zhao, F., Schadendorf, D., Dahlmann, B., Uckert, W., Paschen, A., Mishto, M. and Seifert, U.
European Journal of Immunology 50
(2): 270-283.
February 2020
Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole, T.M., Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Sprüssel, A. ORCID: https://orcid.org/0000-0001-6079-5907, Pfeil, S., Savelyeva, L., Capper, D., Messerschmidt, C. ORCID: https://orcid.org/0000-0001-8632-656X, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Groeneveld-Krentz, S., Eckert, C., Gambara, G., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Finkler, S., Schulte, J.H., Sieber, A., Bluethgen, N. ORCID: https://orcid.org/0000-0002-0171-7447, Regenbrecht, C.R.A., Künkele, A., Lodrini, M., Eggert, A. and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
International Journal of Cancer 146
(4): 1031-1041.
15 February 2020
Phosphosite analysis of the cytomegaloviral mRNA export factor pUL69 reveals serines with critical importance for recruitment of cellular proteins Pin1 and UAP56/URH49.
Thomas, M., Müller, R., Horn, G., Bogdanow, B. ORCID: https://orcid.org/0000-0002-9634-7353, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Milbradt, J., Steingruber, M., Marschall, M., Schilling, E.M., Fossen, T. and Stamminger, T.
Journal of Virology 94
(8): e02151-19.
31 March 2020
Small-molecule dual PLK1 and BRD4 inhibitors are active against preclinical models of pediatric solid tumors.
Timme, N., Han, Y., Liu, S., Yosief, H.O., García, H.D. ORCID: https://orcid.org/0000-0002-2578-3350, Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Klironomos, F., MacArthur, I.C., Szymansky, A. ORCID: https://orcid.org/0000-0003-4797-4526, von Stebut, J. ORCID: https://orcid.org/0000-0001-9811-445X, Bardinet, V. ORCID: https://orcid.org/0000-0002-9583-7043, Dohna, C., Künkele, A., Rolff, J., Hundsdörfer, P., Lissat, A., Seifert, G., Eggert, A., Schulte, J.H., Zhang, W. and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Translational Oncology 13
(2): 221-232.
February 2020
N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma.
Tjaden, B., Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Marquardt, V., Simon, M. ORCID: https://orcid.org/0000-0001-7213-9499, Trajkovic-Arsic, M., Kouril, T., Siebers, B. ORCID: https://orcid.org/0000-0002-9905-541X, Lisec, J., Siveke, J.T. ORCID: https://orcid.org/0000-0002-8772-4778, Schulte, J.H., Benary, U. ORCID: https://orcid.org/0000-0001-7801-8639, Remke, M., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868 and Schramm, A. ORCID: https://orcid.org/0000-0001-7670-7529
Scientific Reports 10
(1): 7157.
28 April 2020
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage.
Toboso-Navasa, A. ORCID: https://orcid.org/0000-0001-8560-1507, Gunawan, A. ORCID: https://orcid.org/0000-0002-4136-3620, Morlino, G., Nakagawa, R. ORCID: https://orcid.org/0000-0003-2511-0444, Taddei, A., Damry, D., Patel, Y. ORCID: https://orcid.org/0000-0003-1787-0726, Chakravarty, P., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Kassiotis, G., Brink, R. ORCID: https://orcid.org/0000-0002-9586-3655, Eilers, M. and Calado, D.P. ORCID: https://orcid.org/0000-0001-8239-7184
Journal of Experimental Medicine 217
(7): e20191933.
6 July 2020
Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells.
Toews, K., Grunewald, L., Schwiebert, S., Klaus, A., Winkler, A., Ali, S., Zirngibl, F., Astrahantseff, K., Wagner, D.L., Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X, Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893, Schulte, J.H., Ochsenreither, S., Eggert, A. and Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412
Molecular Carcinogenesis 59
(7): 724-273.
July 2020
CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia.
Tran, N.T. ORCID: https://orcid.org/0000-0003-0896-8641, Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Wulf-Goldenberg, A., Stecklum, M., Strauß, G., Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696
Molecular Therapy 28
(12): 2621-2634.
2 December 2020
Protocol for efficient CRISPR/Cas9/AAV-mediated homologous recombination in mouse hematopoietic stem and progenitor cells.
Tran, N.T. ORCID: https://orcid.org/0000-0003-0896-8641, Trombke, J. ORCID: https://orcid.org/0000-0002-8746-1795, Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370 and Chu, V.T. ORCID: https://orcid.org/0000-0003-1327-8696
STAR Protocols 1
(1): 100028.
19 June 2020
R-chie: a web server and R package for visualizing cis and trans RNA-RNA, RNA-DNA and DNA-DNA interactions.
Tsybulskyi, V. ORCID: https://orcid.org/0009-0002-4141-6291, Mounir, M. and Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479
Nucleic Acids Research 48
(18): e105.
9 October 2020
Therapeutic targeting of preleukemia cells in a mouse model of mutant acute myeloid leukemia.
Uckelmann, H.J. ORCID: https://orcid.org/0000-0003-2048-7357, Kim, S.M. ORCID: https://orcid.org/0000-0003-0015-1821, Wong, E.M., Hatton, C. ORCID: https://orcid.org/0000-0001-9903-4291, Giovinazzo, H., Gadrey, J.Y. ORCID: https://orcid.org/0000-0001-7749-7703, Krivtsov, A.V. ORCID: https://orcid.org/0000-0002-5511-1686, Rücker, F.G., Döhner, K., McGeehan, G.M., Levine, R.L., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Vassiliou, G.S. ORCID: https://orcid.org/0000-0003-4337-8022 and Armstrong, S.A. ORCID: https://orcid.org/0000-0002-9099-4728
Science 367
(6477): 586-590.
31 January 2020
covRNA: discovering covariate associations in large-scale gene expression data.
Urban, L., Remmele, C.W., Dittrich, M., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268 and Müller, T. ORCID: https://orcid.org/0000-0003-3035-7070
BMC Research Notes 13
(1): 92.
24 February 2020
The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review.
Van Paemel, R., Vlug, R., De Preter, K., Van Roy, N., Speleman, F., Willems, L., Lammens, T., Laureys, G., Schleiermacher, G., Tytgat, G.A.M., Astrahantseff, K., Deubzer, H. ORCID: https://orcid.org/0000-0002-6115-4893 and De Wilde, B. ORCID: https://orcid.org/0000-0003-0213-1322
European Journal of Pediatrics 179
: 191-202.
February 2020
Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads.
Vollger, M.R. ORCID: https://orcid.org/0000-0002-8651-1615, Logsdon, G.A. ORCID: https://orcid.org/0000-0003-2396-0656, Audano, P.A. ORCID: https://orcid.org/0000-0002-5187-0415, Sulovari, A., Porubsky, D., Peluso, P., Wenger, A.M., Concepcion, G.T., Kronenberg, Z.N., Munson, K.M. ORCID: https://orcid.org/0000-0001-8413-6498, Baker, C., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Spierings, D.C.J., Lansdorp, P.M., Surti, U., Hunkapiller, M.W. and Eichler, E.E. ORCID: https://orcid.org/0000-0002-8246-4014
Annals of Human Genetics 84
(2): 125-140.
March 2020
Purifying selection against pathogenic mitochondrial DNA in human T cells.
Walker, M.A., Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Karaa, A., Sankaran, V.G., Regev, A. and Mootha, V.K.
New England Journal of Medicine 383
(16): 1556-1563.
15 October 2020
In-vitro and in-vivo investigations into the carbene-gold anticancer drug candidates NHC*-Au-SCSNMe(2) and NHC*-Au-S-GLUC against advanced prostate cancer PC3.
Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Althagafi, D., Curran, D., O'Beirne, C., Mc Carthy, C., Ott, I., Basu, U., Büttner, B., Sterner-Kock, A., Müller-Bunz, H., Sánchez-Sanz, G., Zhu, X. and Tacke, M.
Anti-Cancer Drugs 31
(7): 672-683.
August 2020
Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility.
Warren, W.C. ORCID: https://orcid.org/0000-0003-2255-2730, Harris, R.A. ORCID: https://orcid.org/0000-0002-7333-4752, Haukness, M. ORCID: https://orcid.org/0000-0001-9991-8089, Fiddes, I.T. ORCID: https://orcid.org/0000-0002-1580-7443, Murali, S.C., Fernandes, J. ORCID: https://orcid.org/0000-0002-8625-1796, Dishuck, P.C. ORCID: https://orcid.org/0000-0003-2223-9787, Storer, J.M. ORCID: https://orcid.org/0000-0002-9619-5265, Raveendran, M. ORCID: https://orcid.org/0000-0001-6185-4059, Hillier, L.W., Porubsky, D., Mao, Y. ORCID: https://orcid.org/0000-0002-9648-4278, Gordon, D. ORCID: https://orcid.org/0000-0001-6552-4022, Vollger, M.R. ORCID: https://orcid.org/0000-0002-8651-1615, Lewis, A.P. ORCID: https://orcid.org/0000-0002-6195-4786, Munson, K.M. ORCID: https://orcid.org/0000-0001-8413-6498, DeVogelaere, E., Armstrong, J. ORCID: https://orcid.org/0000-0003-2077-4671, Diekhans, M. ORCID: https://orcid.org/0000-0002-0430-0989, Walker, J.A., Tomlinson, C. ORCID: https://orcid.org/0000-0001-9905-6159, Graves-Lindsay, T.A., Kremitzki, M., Salama, S.R. ORCID: https://orcid.org/0000-0001-6999-7193, Audano, P.A. ORCID: https://orcid.org/0000-0002-5187-0415, Escalona, M. ORCID: https://orcid.org/0000-0003-0213-4777, Maurer, N.W. ORCID: https://orcid.org/0000-0003-0007-7887, Antonacci, F. ORCID: https://orcid.org/0000-0002-5833-6186, Mercuri, L. ORCID: https://orcid.org/0000-0002-3688-4501, Maggiolini, F.A.M. ORCID: https://orcid.org/0000-0001-6832-9388, Catacchio, C.R. ORCID: https://orcid.org/0000-0002-2166-723X, Underwood, J.G., O'Connor, D.H. ORCID: https://orcid.org/0000-0003-2139-470X, Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Korbel, J.O., Ferguson, B. ORCID: https://orcid.org/0000-0002-6992-3538, Kubisch, H.M. ORCID: https://orcid.org/0000-0001-6281-8420, Picker, L. ORCID: https://orcid.org/0000-0003-0546-398X, Kalin, N.H., Rosene, D., Levine, J. ORCID: https://orcid.org/0000-0003-4177-6406, Abbott, D.H., Gray, S.B. ORCID: https://orcid.org/0000-0002-8816-0898, Sanchez, M.M. ORCID: https://orcid.org/0000-0001-7701-2892, Kovacs-Balint, Z.A., Kemnitz, J.W. ORCID: https://orcid.org/0000-0001-6511-404X, Thomasy, S.M. ORCID: https://orcid.org/0000-0001-5617-9677, Roberts, J.A. ORCID: https://orcid.org/0000-0002-0159-6112, Kinnally, E.L., Capitanio, J.P. ORCID: https://orcid.org/0000-0002-3680-1323, Skene, J.H.P. ORCID: https://orcid.org/0000-0003-3205-0697, Platt, M. ORCID: https://orcid.org/0000-0003-3912-8821, Cole, S.A. ORCID: https://orcid.org/0000-0002-2651-0127, Green, R.E. ORCID: https://orcid.org/0000-0003-0516-5827, Ventura, M. ORCID: https://orcid.org/0000-0001-7762-8777, Wiseman, R.W. ORCID: https://orcid.org/0000-0002-7682-7085, Paten, B. ORCID: https://orcid.org/0000-0001-8863-3539, Batzer, M.A. ORCID: https://orcid.org/0000-0001-5699-863X, Rogers, J. ORCID: https://orcid.org/0000-0002-7374-6490 and Eichler, E.E.
Science 370
(6523): eabc6617.
18 December 2020
Pervasive chromosomal instability and karyotype order in tumour evolution.
Watkins, T.B.K. ORCID: https://orcid.org/0000-0001-7414-737X, Lim, E.L., Petkovic, M. ORCID: https://orcid.org/0000-0003-2875-216X, Elizalde, S. ORCID: https://orcid.org/0000-0003-4116-2455, Birkbak, N.J. ORCID: https://orcid.org/0000-0003-1613-9587, Wilson, G.A., Moore, D.A., Grönroos, E. ORCID: https://orcid.org/0000-0001-8303-5409, Rowan, A., Dewhurst, S.M., Demeulemeester, J. ORCID: https://orcid.org/0000-0002-2660-2478, Dentro, S.C., Horswell, S. ORCID: https://orcid.org/0000-0003-2787-1933, Au, L., Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Escudero, M. ORCID: https://orcid.org/0000-0002-1336-815X, Rosenthal, R., Bakir, M.A., Xu, H., Litchfield, K., Lu, W.T. ORCID: https://orcid.org/0000-0002-1405-4806, Mourikis, T.P., Dietzen, M., Spain, L., Cresswell, G.D. ORCID: https://orcid.org/0000-0003-3303-068X, Biswas, D. ORCID: https://orcid.org/0000-0001-9141-5188, Lamy, P., Nordentoft, I., Harbst, K. ORCID: https://orcid.org/0000-0002-8225-1510, Castro-Giner, F. ORCID: https://orcid.org/0000-0001-6111-0754, Yates, L.R., Caramia, F. ORCID: https://orcid.org/0000-0002-5086-2544, Jaulin, F. ORCID: https://orcid.org/0000-0002-5110-1800, Vicier, C., Tomlinson, I.P.M., Brastianos, P.K., Cho, R.J., Bastian, B.C. ORCID: https://orcid.org/0000-0003-1836-6062, Dyrskjøt, L. ORCID: https://orcid.org/0000-0001-7061-9851, Jönsson, G.B., Savas, P. ORCID: https://orcid.org/0000-0001-5999-428X, Loi, S. ORCID: https://orcid.org/0000-0001-6137-9171, Campbell, P.J. ORCID: https://orcid.org/0000-0002-3921-0510, Andre, F. ORCID: https://orcid.org/0000-0001-5795-8357, Luscombe, N.M. ORCID: https://orcid.org/0000-0001-5293-4778, Steeghs, N., Tjan-Heijnen, V.C.G., Szallasi, Z., Turajlic, S. ORCID: https://orcid.org/0000-0001-8846-136X, Jamal-Hanjani, M., Van Loo, P. ORCID: https://orcid.org/0000-0003-0292-1949, Bakhoum, S.F., Schwarz, R.F. ORCID: https://orcid.org/0000-0001-9155-4268, McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045 and Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018
Nature 587
(7832): 126-132.
5 November 2020
PEDL: extracting protein-protein associations using deep language models and distant supervision.
Weber, L. ORCID: https://orcid.org/0000-0002-2499-472X, Thobe, K. ORCID: https://orcid.org/0000-0001-8883-0620, Migueles Lozano, O.A. ORCID: https://orcid.org/0009-0009-6570-3659, Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868 and Leser, U.
Bioinformatics 36
(Suppl 1): i490-i498.
July 2020
4EHP and GIGYF1/2 mediate translation-coupled messenger RNA decay.
Weber, R., Chung, M.Y., Keskeny, C. ORCID: https://orcid.org/0000-0003-3297-7329, Zinnall, U. ORCID: https://orcid.org/0000-0002-0782-7751, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Valkov, E., Izaurralde, E. and Igreja, C.
Cell Reports 33
(2): 108262.
13 October 2020
Integrative functional genomics decodes herpes simplex virus 1.
Whisnant, A.W. ORCID: https://orcid.org/0000-0003-2039-2809, Jürges, C.S. ORCID: https://orcid.org/0000-0001-5617-6601, Hennig, T., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Prusty, B. ORCID: https://orcid.org/0000-0001-7051-4670, Rutkowski, A.J., L'hernault, A., Djakovic, L. ORCID: https://orcid.org/0000-0002-9368-9403, Göbel, M., Döring, K., Menegatti, J., Antrobus, R., Matheson, N.J. ORCID: https://orcid.org/0000-0002-3318-1851, Künzig, F.W.H. ORCID: https://orcid.org/0000-0003-3730-3905, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Bielow, C. ORCID: https://orcid.org/0000-0001-5756-3988, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Liang, C. ORCID: https://orcid.org/0000-0002-0305-2522, Dandekar, T. ORCID: https://orcid.org/0000-0003-1886-7625, Zimmer, R., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Grässer, F., Lehner, P.J., Friedel, C.C. ORCID: https://orcid.org/0000-0003-3569-4877, Erhard, F. ORCID: https://orcid.org/0000-0002-3574-6983 and Dölken, L. ORCID: https://orcid.org/0000-0002-4651-3544
Nature Communications 11
(1): 2038.
27 April 2020
Ubiquitination and ubiquitin-like modifications in multiple myeloma: biology and therapy.
Wirth, M. ORCID: https://orcid.org/0000-0002-8340-0872, Schick, M. ORCID: https://orcid.org/0009-0003-8626-0611, Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958 and Krönke, J.
Cancers 12
(12): 3764.
14 December 2020
Responses of gastric epithelial stem cells and their niche to Helicobacter pylori infection.
Wizenty, J., Tacke, F. and Sigal, M. ORCID: https://orcid.org/0000-0003-4772-0761
Annals of Translational Medicine 8
(8): 568.
April 2020
Wegbereiter der modernen Krebsforschung: Theodor Boveri und Otto Warburg [Pioneers of modern cancer research: Theodor Boveri and Otto Warburg].
Wunderlich, V.
BIOspektrum 26
(6): 687-690.
November 2020
50 Jahre Reverse Transkriptase [50 years of reverse transcriptase].
Wunderlich, V.
BIOspektrum 26
(3): 343-344.
May 2020
Clinical outcome in patients with carcinoma of the esophagogastric junction treated with neoadjuvant radiochemotherapy or perioperative chemotherapy: a two-enter retrospective analysis.
Wundsam, H.V., Doleschal, B., Prommer, R., Venhoda, C., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Petzer, A., Metz-Gercek, S. and Rumpold, H.
Oncology 98
(10): 706-713.
October 2020
Non-thermal effects of radiofrequency electromagnetic fields.
Wust, P., Kortüm, B. ORCID: https://orcid.org/0000-0003-3734-6665, Strauss, U., Nadobny, J., Zschaeck, S., Beck, M., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Ghadjar, P.
Scientific Reports 10
(1): 13488.
10 August 2020
hGBP1 coordinates chlamydia restriction and inflammasome activation through sequential GTP hydrolysis.
Xavier, A. ORCID: https://orcid.org/0000-0002-8801-1307, Al-Zeer, M.A., Meyer, T.F. and Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414
Cell Reports 31
(7): 107667.
19 May 2020
Overactivation of the NF-κB pathway impairs molar enamel formation.
Yamada, A., Kawasaki, M., Miake, Y., Yamada, Y., Blackburn, J., Kawasaki, K., Trakanant, S., Nagai, T., Nihara, J., Kudo, T., Meguro, F., Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Liu, B., Hu, Y., Page, A., Ramírez, Á., Sharpe, P.T., Maeda, T., Takagi, R. and Ohazama, A. ORCID: https://orcid.org/0000-0002-3496-0347
Oral Diseases 26
(7): 1513-1522.
October 2020
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf, R.Z., Saez, B., Sharda, A., van Gastel, N. ORCID: https://orcid.org/0000-0002-0563-3590, Yu, V.W.C. ORCID: https://orcid.org/0000-0002-6658-0285, Baryawno, N., Scadden, E.W., Acharya, S., Chattophadhyay, S., Huang, C., Viswanathan, V. ORCID: https://orcid.org/0000-0001-9878-3629, S'aulis, D., Cobert, J., Sykes, D.B. ORCID: https://orcid.org/0000-0002-9788-0221, Keibler, M.A., Das, S., Hutchinson, J.N. ORCID: https://orcid.org/0000-0002-7804-7576, Churchill, M. ORCID: https://orcid.org/0000-0001-7202-3891, Mukherjee, S., Lee, D. ORCID: https://orcid.org/0000-0001-6828-401X, Mercier, F., Doench, J., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Logan, D.J., Schreiber, S., Stephanopoulos, G., Rizzo, W.B. and Scadden, D.T.
Blood 136
(11): 1303-1316.
10 September 2020
Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta.
Yvernogeau, L., Klaus, A., Maas, J., Morin-Poulard, I., Weijts, B., Schulte-Merker, S., Berezikov, E., Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290 and Robin, C.
Blood 136
(7): 831-844.
13 August 2020
Monogenic variants in dystonia: an exome-wide sequencing study.
Zech, M., Jech, R., Boesch, S., Škorvánek, M., Weber, S., Wagner, M., Zhao, C., Jochim, A., Necpál, J., Dincer, Y., Vill, K., Distelmaier, F., Stoklosa, M., Krenn, M., Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Bock-Bierbaum, T. ORCID: https://orcid.org/0000-0003-0843-2716, Fečíková, A., Havránková, P., Roth, J., Příhodová, I., Adamovičová, M., Ulmanová, O., Bechyně, K., Danhofer, P., Veselý, B., Haň, V., Pavelekova, P., Gdovinová, Z., Mantel, T., Meindl, T., Sitzberger, A., Schröder, S., Blaschek, A., Roser, T., Bonfert, M.V., Haberlandt, E., Plecko, B., Leineweber, B., Berweck, S., Herberhold, T., Langguth, B., Švantnerová, J., Minár, M., Ramos-Rivera, G.A., Wojcik, M.H., Pajusalu, S., Õunap, K., Schatz, U.A., Pölsler, L., Milenkovic, I., Laccone, F., Pilshofer, V., Colombo, R., Patzer, S., Iuso, A., Vera, J., Troncoso, M., Fang, F., Prokisch, H., Wilbert, F., Eckenweiler, M., Graf, E., Westphal, D.S., Riedhammer, K.M., Brunet, T., Alhaddad, B., Berutti, R., Strom, T.M., Hecht, M., Baumann, M., Wolf, M., Telegrafi, A., Person, R.E., Zamora, F.M., Henderson, L.B., Weise, D., Musacchio, T., Volkmann, J., Szuto, A., Becker, J., Cremer, K., Sycha, T., Zimprich, F., Kraus, V., Makowski, C., Gonzalez-Alegre, P., Bardakjian, T.M., Ozelius, L.J., Vetro, A., Guerrini, R., Maier, E., Borggraefe, I., Kuster, A., Wortmann, S.B., Hackenberg, A., Steinfeld, R., Assmann, B., Staufner, C., Opladen, T., Růžička, E., Cohn, R.D., Dyment, D., Chung, W.K., Engels, H., Ceballos-Baumann, A., Ploski, R., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Haslinger, B., Mall, V., Oexle, K. and Winkelmann, J.
Lancet Neurology 19
(11): 908-918.
November 2020
Long noncoding RNA TYKRIL plays a role in pulmonary hypertension via the p53-mediated regulation of PDGFRβ.
Zehendner, C.M., Valasarajan, C., Werner, A., Boeckel, J.N., Bischoff, F.C., John, D., Weirick, T., Glaser, S.F., Rossbach, O., Jaé, N., Demolli, S., Khassafi, F., Yuan, K., de Jesus Perez, V.A., Michalik, K.M., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Seeger, W., Guenther, A., Wasnick, R.M., Uchida, S., Zeiher, A.M., Dimmeler, S. and Pullamsetti, S.S. ORCID: https://orcid.org/0000-0003-0440-8831
American Journal of Respiratory and Critical Care Medicine 202
(10): 1445-1457.
15 November 2020
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Zhang, Y., Chen, F., Fonseca, N.A. ORCID: https://orcid.org/0000-0003-4832-578X, He, Y., Fujita, M. ORCID: https://orcid.org/0000-0002-1457-6233, Nakagawa, H., Zhang, Z., Brazma, A. ORCID: https://orcid.org/0000-0001-5988-7409 and Creighton, C.J. ORCID: https://orcid.org/0000-0002-6090-703X
Nature Communications 11
(1): 736.
5 February 2020
Sinusoidal obstruction syndrome following myeloablative therapy and tranexamic acid treatment for hemorrhage in two patients with neuroblastoma.
Zirngibl, F., Flemmig, C., Lang, P., Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412, Eggert, A., Schulte, J.H. and Deubzer, H.E. ORCID: https://orcid.org/0000-0002-6115-4893
Children 7
(11): 198.
November 2020
C/EBPβ-dependent epigenetic memory induces trained immunity in hematopoietic stem cells.
de Laval, B., Maurizio, J., Kandalla, P.K., Brisou, G., Simonnet, L., Huber, C., Gimenez, G., Matcovitch-Natan, O., Reinhardt, S., David, E., Mildner, A. ORCID: https://orcid.org/0000-0002-2019-8427, Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X, Nadel, B., Bordi, C., Amit, I., Sarrazin, S. and Sieweke, M.H. ORCID: https://orcid.org/0000-0002-3228-9537
Cell Stem Cell 26
(5): 657-674.
May 2020
USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells.
van den Berk, P., Lancini, C. ORCID: https://orcid.org/0000-0001-9880-678X, Company, C. ORCID: https://orcid.org/0000-0002-7975-0642, Serresi, M. ORCID: https://orcid.org/0000-0001-6839-8658, Sanchez-Bailon, M.P. ORCID: https://orcid.org/0000-0001-6929-2273, Hulsman, D., Pritchard, C., Song, J.Y., Schmitt, M.J. ORCID: https://orcid.org/0000-0001-8296-5858, Tanger, E., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Huijbers, I.J., Jacobs, H. ORCID: https://orcid.org/0000-0001-6227-9850, van Lohuizen, M., Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251 and Citterio, E. ORCID: https://orcid.org/0000-0003-2347-3495
Cell Reports 33
(13): 108533.
29 December 2020
Interruption of the CXCL13/CXCR5 chemokine axis enhances plasma IgM levels and attenuates atherosclerosis development.
van der Vorst, E.P.C., Daissormont, I., Aslani, M., Seijkens, T., Wijnands, E., Lutgens, E., Duchene, J., Santovito, D., Döring, Y., Halvorsen, B., Aukrust, P., Weber, C., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Biessen, E.A.L.
Thrombosis and Haemostasis 120
(2): 344-347.
February 2020
2019
Impaired human hematopoiesis due to a cryptic intronic splicing mutation.
Abdulhay, N.J., Fiorini, C., Verboon, J.M., Ludwig, L.S. ORCID: https://orcid.org/0000-0002-2916-2164, Ulirsch, J.C., Zieger, B., Lareau, C.A. ORCID: https://orcid.org/0000-0003-4179-4807, Mi, X., Roy, A. ORCID: https://orcid.org/0000-0001-8607-5748, Obeng, E.A. ORCID: https://orcid.org/0000-0002-8691-7439, Erlacher, M. ORCID: https://orcid.org/0000-0002-7261-1447, Gupta, N., Gabriel, S.B., Ebert, B.L., Niemeyer, C.M., Khoriaty, R.N., Ancliff, P., Gazda, H.T., Wlodarski, M.W. and Sankaran, V.G. ORCID: https://orcid.org/0000-0003-0044-443X
Journal of Experimental Medicine 216
(5): 1050-1060.
6 May 2019
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.
Ackermann, T. ORCID: https://orcid.org/0000-0002-9982-8697, Hartleben, G., Müller, C. ORCID: https://orcid.org/0000-0003-1974-4053, Mastrobuoni, G. ORCID: https://orcid.org/0000-0003-4509-1295, Groth, M. ORCID: https://orcid.org/0000-0002-9199-8990, Sterken, B.A. ORCID: https://orcid.org/0000-0003-1327-1734, Zaini, M.A., Youssef, S.A. ORCID: https://orcid.org/0000-0002-6402-9975, Zuidhof, H.R. ORCID: https://orcid.org/0000-0002-4893-633X, Krauss, S.R., Kortman, G., de Haan, G. ORCID: https://orcid.org/0000-0001-9706-0138, de Bruin, A. ORCID: https://orcid.org/0000-0001-8579-2649, Wang, Z.Q., Platzer, M. ORCID: https://orcid.org/0000-0003-0596-8582, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299 and Calkhoven, C.F. ORCID: https://orcid.org/0000-0001-6318-7210
Communications Biology 2
: 208.
14 June 2019
Pressurized intraperitoneal aerosol chemotherapy and its effect on gastric-cancer-derived peritoneal metastases: an overview.
Alberto, M. ORCID: https://orcid.org/0000-0002-6249-6932, Brandl, A., Garg, P.K., Gül-Klein, S., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Rau, B.
Clinical and Experimental Metastasis 36
(1): 1-14.
February 2019
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing.
Andersch, L., Radke, J., Klaus, A., Schwiebert, S., Winkler, A., Schumann, E., Grunewald, L., Zirngibl, F., Flemmig, C., Jensen, M.C., Rossig, C., Joussen, A., Henssen, A. ORCID: https://orcid.org/0000-0003-1534-778X, Eggert, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201 and Künkele, A. ORCID: https://orcid.org/0000-0002-8406-5412
BMC Cancer 19
(1): 895.
9 September 2019
Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Horst, D., Rau, B., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Treese, C. ORCID: https://orcid.org/0000-0001-9120-6773
Pathology Research and Practice 215
(11): 152662.
November 2019
Saffron: The golden spice with therapeutic properties on digestive diseases.
Ashktorab, H. ORCID: https://orcid.org/0000-0002-4048-4666, Soleimani, A., Singh, G., Amr, A. ORCID: https://orcid.org/0000-0001-8888-1102, Tabtabaei, S., Latella, G., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X, Akhondzadeh, S., Solanki, N., Gondré-Lewis, M.C., Habtezion, A. and Brim, H.
Nutrients 11
(5): 943.
26 April 2019
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembling cofactors ASPL/PUX1.
Banchenko, S. ORCID: https://orcid.org/0000-0003-2166-1222, Arumughan, A., Petrović, S., Schwefel, D. ORCID: https://orcid.org/0000-0002-2945-0908, Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X and Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850
Structure 27
(12): 1830-1841.
3 December 2019
In contrast to Western diet, a plant-based, high-fat, low-sugar diet does not exacerbate retinal endothelial injury in streptozotocin-induced diabetes.
Barakat, A., Nakao, S., Zandi, S., Sun, D., Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Hayes, K.C. and Hafezi-Moghadam, A.
FASEB Journal 33
(9): 10327-10338.
September 2019
Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Balogh, A. ORCID: https://orcid.org/0000-0001-8756-747X, Yakoub, M., Homann, S., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, Höges, S., Tsvetkov, D. ORCID: https://orcid.org/0000-0002-6472-971X, Krannich, A. ORCID: https://orcid.org/0000-0002-4025-6495, Wundersitz, S., Avery, E.G. ORCID: https://orcid.org/0000-0002-9094-1423, Haase, N. ORCID: https://orcid.org/0000-0003-0727-1738, Kräker, K. ORCID: https://orcid.org/0000-0002-4032-5382, Hering, L., Maase, M., Kusche-Vihrog, K., Grandoch, M., Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934, Zhumadilov, Z., Kozhakhmetov, S., Kushugulova, A., Eckardt, K.U., Dechend, R. ORCID: https://orcid.org/0000-0001-6636-3080, Rump, L.C., Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Stegbauer, J. and Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364
Circulation 139
(11): 1407-1421.
12 March 2019
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
Basheer, F., Giotopoulos, G. ORCID: https://orcid.org/0000-0003-1390-6592, Meduri, E., Yun, H., Mazan, M., Sasca, D., Gallipoli, P. ORCID: https://orcid.org/0000-0001-7254-2253, Marando, L., Gozdecka, M., Asby, R. ORCID: https://orcid.org/0000-0001-5077-3798, Sheppard, O., Dudek, M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Döhner, H. ORCID: https://orcid.org/0000-0003-2116-5536, Dillon, R., Freeman, S., Ottmann, O., Burnett, A., Russell, N., Papaemmanuil, E., Hills, R., Campbell, P., Vassiliou, G.S.. ORCID: https://orcid.org/0000-0003-4337-8022 and Huntly, B.J.P. ORCID: https://orcid.org/0000-0003-0312-161X
Journal of Experimental Medicine 216
(4): 966-981.
1 April 2019
Analysis of correlation-based biomolecular networks from different omics data by fitting stochastic block models.
Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Rajapakse, J.C. and Azuaje, F.
F1000Research 8
: 465.
27 August 2019
Of gene expression and cell division time: a mathematical framework for advanced differential gene expression and data analysis.
Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Schuchhardt, J., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868 and Busse, D.
Cell Systems 9
(6): 569-579.
18 December 2019
Controlling nuclear NF-κB dynamics by β-TrCP-insights from a computational model.
Benary, U. ORCID: https://orcid.org/0000-0001-7801-8639 and Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868
Biomedicines 7
(2): 40.
27 May 2019
Modelling the DNA topology: the effect of the loop bending on G-quadruplex stability.
Bergues-Pupo, A.E. ORCID: https://orcid.org/0000-0002-6568-4138, Falo, F. and Fiasconaro, A.
Journal of Statistical Mechanics: Theory and Experiment 2019
(9): 094004.
2 September 2019
Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.
Bhaskara, R.M. ORCID: https://orcid.org/0000-0002-7742-0391, Grumati, P., Garcia-Pardo, J., Kalayil, S., Covarrubias-Pinto, A., Chen, W., Kudryashev, M. ORCID: https://orcid.org/0000-0003-3550-6274, Dikic, I. ORCID: https://orcid.org/0000-0001-8156-9511 and Hummer, G. ORCID: https://orcid.org/0000-0001-7768-746X
Nature Communications 10
(1): 2370.
30 May 2019
A clonal expression biomarker associates with lung cancer mortality.
Biswas, D., Birkbak, N.J. ORCID: https://orcid.org/0000-0003-1613-9587, Rosenthal, R., Hiley, C.T., Lim, E.L., Papp, K. ORCID: https://orcid.org/0000-0003-0619-8233, Boeing, S., Krzystanek, M., Djureinovic, D., La Fleur, L., Greco, M., Döme, B., Fillinger, J., Brunnström, H. ORCID: https://orcid.org/0000-0001-7402-138X, Wu, Y., Moore, D.A., Skrzypski, M., Abbosh, C., Litchfield, K., Al Bakir, M., Watkins, T.B.K. ORCID: https://orcid.org/0000-0001-7414-737X, Veeriah, S., Wilson, G.A., Jamal-Hanjani, M., Moldvay, J., Botling, J., Chinnaiyan, A.M., Micke, P., Hackshaw, A., Bartek, J., Csabai, I., Szallasi, Z., Herrero, J. ORCID: https://orcid.org/0000-0001-7313-717X, McGranahan, N. ORCID: https://orcid.org/0000-0001-9537-4045 and Swanton, C. ORCID: https://orcid.org/0000-0002-4299-3018
Nature Medicine 25
(10): 1540-1548.
October 2019
Identification and ranking of recurrent neo-epitopes in cancer.
Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Holtgrewe, M. ORCID: https://orcid.org/0000-0002-3051-1763, Dhamodaran, A. ORCID: https://orcid.org/0000-0001-7711-9593, Messerschmidt, C. ORCID: https://orcid.org/0000-0001-8632-656X, Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632
BMC Medical Genomics 12
: 171.
27 November 2019
getITD for FLT3-ITD-based MRD monitoring in AML.
Blätte, T.J., Schmalbrock, L.K., Skambraks, S., Lux, S., Cocciardi, S., Dolnik, A., Döhner, H., Döhner, K. and Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Leukemia 33
(10): 2535-2539.
October 2019
Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N., Perret, M.F., Glaser, S.F., Seeger, T., Heumüller, A.W., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, John, D., Kokot, K.E., Katus, H.A., Haas, J., Lackner, M.K., Kayvanpour, E., Grabe, N., Dieterich, C. ORCID: https://orcid.org/0000-0001-9468-6311, von Haehling, S., Ebner, N., Hünecke, S., Leuschner, F., Fichtlscherer, S., Meder, B., Zeiher, A.M., Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126
: 13-22.
January 2019
The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A. ORCID: https://orcid.org/0000-0001-9118-050X, Babila, J.T., Wiglenda, T. ORCID: https://orcid.org/0000-0002-8460-9459, Diez, L. ORCID: https://orcid.org/0000-0003-3101-0191, Jacob, M., Nietfeld, W., Huska, M.R. ORCID: https://orcid.org/0000-0002-0912-745X, Haenig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Groenke, N. ORCID: https://orcid.org/0000-0002-6927-3774, Buntru, A., Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Meier, J.C. ORCID: https://orcid.org/0000-0001-5574-3336, Vannoni, E., Erck, C., Friedrich, B., Martens, H., Neuendorf, N., Schnoegl, S., Wolfer, D.P., Loos, M., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Andrade-Navarro, M.A. and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Cell Chemical Biology 26
(1): 109-120.
17 January 2019
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B. ORCID: https://orcid.org/0000-0002-9634-7353, Wang, X. ORCID: https://orcid.org/0000-0002-7572-6354, Eichelbaum, K., Sadewasser, A. ORCID: https://orcid.org/0000-0002-8491-3952, Husic, I., Paki, K., Budt, M., Hergeselle, M., Vetter, B., Hou, J., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Wiebusch, L. ORCID: https://orcid.org/0000-0002-7210-6731, Meyer, I.M. ORCID: https://orcid.org/0000-0002-4048-3479, Wolff, T. ORCID: https://orcid.org/0000-0001-7688-236X and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Nature Communications 10
(1): 5518.
4 December 2019
New targeted agents in acute myeloid leukemia: new hope on the rise.
Bohl, S.R., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Rücker, F.G.
International Journal of Molecular Sciences 20
(8)
23 April 2019
WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N., Gloaguen, Y. ORCID: https://orcid.org/0000-0003-0493-8592, Opialla, T. ORCID: https://orcid.org/0000-0001-9527-8061, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Sicard, E., Royer, A.L., Le Bizec, B. ORCID: https://orcid.org/0000-0002-0600-5895, Durand, S., Migné, C., Pétéra, M., Pujos-Guillot, E., Giacomoni, F. ORCID: https://orcid.org/0000-0001-6063-4214, Guitton, Y. ORCID: https://orcid.org/0000-0002-4479-0636, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Kirwan, J. ORCID: https://orcid.org/0000-0002-5423-1651
Metabolites 9
(9): 171.
21 August 2019
Crowdfunded whole-genome sequencing of the celebrity cat Lil BUB identifies causal mutations for her osteopetrosis and polydactyly.
Bridavsky, M., Kuhl, H., Woodruf, A., Kornak, U., Timmermann, B., Mages, N., Lupiáñez, D.G. ORCID: https://orcid.org/0000-0002-3165-036X, Symmons, O. and Ibrahim, D.M.
bioRxiv
: 556761.
22 February 2019
Time-resolved DNA release from an O-antigen specific Salmonella bacteriophage with a contractile tail.
Broeker, N.K., Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Valleriani, A., Stephan, M.S., Andres, D., Koetz, J., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Barbirz, S.
Journal of Biological Chemistry 294
(31): 11751-11761.
2 August 2019
IDH2 inhibition: another piece to the puzzle.
Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510
Blood 133
(7): 625-626.
14 February 2019
Isolation and long-term cultivation of mouse alveolar macrophages.
Busch, C. J.-L. ORCID: https://orcid.org/0009-0003-0131-3076, Favret, J., Geirsdóttir, L., Molawi, K. and Sieweke, M.H. ORCID: https://orcid.org/0000-0002-3228-9537
Bio-protocol 9
(14): e3302.
20 July 2019
Analysis of the CDK4/6 cell cycle pathway in leiomyosarcomas as a potential target for inhibition by palbociclib.
Böhm, M.J. ORCID: https://orcid.org/0000-0002-7272-5831, Marienfeld, R., Jäger, D., Mellert, K., von Witzleben, A., Brüderlein, S., Wittau, M., von Baer, A., Schultheiss, M., Mayer-Steinacker, R., Rücker, F.G., Möller, P., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Barth, T.F.E. ORCID: https://orcid.org/0000-0002-3379-6311
Sarcoma 2019
: 3914232.
21 January 2019
Multi-platform discovery of haplotype-resolved structural variation in human genomes.
Chaisson, M.J.P., Sanders, A.D. ORCID: https://orcid.org/0000-0003-3945-0677, Zhao, X. ORCID: https://orcid.org/0000-0003-4036-9577, Malhotra, A., Porubsky, D., Rausch, T. ORCID: https://orcid.org/0000-0001-5773-5620, Gardner, E.J. ORCID: https://orcid.org/0000-0001-9671-1533, Rodriguez, O.L., Guo, L., Collins, R.L., Fan, X., Wen, J., Handsaker, R.E. ORCID: https://orcid.org/0000-0002-3128-3547, Fairley, S., Kronenberg, Z.N., Kong, X., Hormozdiari, F., Lee, D., Wenger, A.M. ORCID: https://orcid.org/0000-0003-1183-0432, Hastie, A.R., Antaki, D. ORCID: https://orcid.org/0000-0003-0381-7801, Anantharaman, T., Audano, P.A. ORCID: https://orcid.org/0000-0002-5187-0415, Brand, H., Cantsilieris, S., Cao, H., Cerveira, E., Chen, C., Chen, X. ORCID: https://orcid.org/0000-0002-2536-165X, Chin, C.S. ORCID: https://orcid.org/0000-0003-4394-2455, Chong, Z. ORCID: https://orcid.org/0000-0001-5750-1808, Chuang, N.T., Lambert, C.C., Church, D.M. ORCID: https://orcid.org/0000-0003-4264-1853, Clarke, L. ORCID: https://orcid.org/0000-0002-5989-6898, Farrell, A., Flores, J., Galeev, T., Gorkin, D.U. ORCID: https://orcid.org/0000-0003-4944-4107, Gujral, M., Guryev, V., Heaton, W.H., Korlach, J. ORCID: https://orcid.org/0000-0003-3047-4250, Kumar, S., Kwon, J.Y., Lam, E.T., Lee, J.E., Lee, J. ORCID: https://orcid.org/0000-0002-3492-1102, Lee, W.P., Lee, S.P., Li, S., Marks, P., Viaud-Martinez, K., Meiers, S., Munson, K.M. ORCID: https://orcid.org/0000-0001-8413-6498, Navarro, F.C.P. ORCID: https://orcid.org/0000-0002-5640-9070, Nelson, B.J., Nodzak, C., Noor, A., Kyriazopoulou-Panagiotopoulou, S., Pang, A.W.C., Qiu, Y. ORCID: https://orcid.org/0000-0002-0539-9714, Rosanio, G., Ryan, M., Stütz, A., Spierings, D.C.J., Ward, A., Welch, A.E., Xiao, M., Xu, W., Zhang, C., Zhu, Q., Zheng-Bradley, X., Lowy, E.
![[feed]](/style/images/feed-icon-14x14.png){kind=icon}