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2019

Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N. and Perret, M.F. and Glaser, S.F. and Seeger, T. and Heumüller, A.W. and Chen, W. and John, D. and Kokot, K.E. and Katus, H.A. and Haas, J. and Lackner, M.K. and Kayvanpour, E. and Grabe, N. and Dieterich, C. and von Haehling, S. and Ebner, N. and Hünecke, S. and Leuschner, F. and Fichtlscherer, S. and Meder, B. and Zeiher, A.M. and Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126 : 13-22. January 2019

Genotoxic stress-induced senescence.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1896 : 93-105. 2019

2018

Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.
Arends, C.M. and Galan-Sousa, J. and Hoyer, K. and Chan, W. and Jäger, M. and Yoshida, K. and Seemann, R. and Noerenberg, D. and Waldhueter, N. and Fleischer-Notter, H. and Christen, F. and Schmitt, C.A. and Dörken, B. and Pelzer, U. and Sinn, M. and Zemojtel, T. and Ogawa, S. and Märdian, S. and Schreiber, A. and Kunitz, A. and Krüger, U. and Bullinger, L. and Mylonas, E. and Frick, M. and Damm, F.
Leukemia 32 (9): 1908-1919. September 2018

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K. and Kranz, A. and Fohgrub, J. and Jolly, A. and Bledau, A.S. and Di Virgilio, M. and Lesche, M. and Dahl, A. and Höfer, T. and Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018

Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.
Arnhold, V. and Schmelz, K. and Proba, J. and Winkler, A. and Wünschel, J. and Toedling, J. and Deubzer, H.E. and Künkele, A. and Eggert, A. and Schulte, J.H. and Hundsdoerfer, P.
Oncotarget 9 (2): 2304-2319. 2018

A comparative analysis of human bone marrow-resident and peripheral memory B cells.
Becker, S.C. and Szyska, M. and Mensen, A. and Hellwig, K. and Otto, R. and Olfe, L. and Volk, H.D. and Dörner, T. and Dörken, B. and Scheibenbogen, C. and Schröder, J. and Hocke, A.C. and Na, I.K.
Journal of Allergy and Clinical Immunology 141 (5): 1911-1913. May 2018

The c-Myc/miR17-92/PTEN axis tunes PI3K activity to control expression of recombination activating genes in early B cell development.
Benhamou, D. and Labi, V. and Getahun, A. and Benchetrit, E. and Dowery, R. and Rajewsky, K. and Cambier, J.C. and Melamed, D.
Frontiers in Immunology 9 : 2715. November 2018

Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues.
Benndorf, R. and Gilmont, R.R. and Hirano, S. and Ransom, R.F. and Jungblut, P.R. and Bommer, M. and Goldman, J.E. and Welsh, M.J.
Cell Stress & Chaperones 23 (5): 813-826. September 2018

Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer.
Berndt, N. and Egners, A. and Mastrobuoni, G. and Vvedenskaya, O. and Fragoulis, A. and Dugourd, A. and Bulik, S. and Pietzke, M. and Bielow, C. and van Gassel, R. and Olde Damink, S. and Erdem, M. and Saez-Rodriguez, J. and Holzhütter, H.G. and Kempa, S. and Cramer, T.
bioRxiv : 275040. 5 March 2018

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J. and Kieback, E. and Marino, S.F. and Oden, F. and Westermann, J. and Chmielewski, M. and Abken, H. and Uckert, W. and Höpken, U.E. and Rehm, A.
Molecular Therapy 26 (8): 1906-1920. 1 August 2018

The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A. and Babila, J.T. and Wiglenda, T. and Diez, L. and Jacob, M. and Nietfeld, W. and Huska, M.R. and Haenig, C. and Groenke, N. and Buntru, A. and Blanc, E. and Meier, J.C. and Vannoni, E. and Erck, C. and Friedrich, B. and Martens, H. and Neuendorf, N. and Schnoegl, S. and Wolfer, D.P. and Loos, M. and Beule, D. and Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 21 October 2018 (In Press)

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B. and Eichelbaum, K. and Sadewasser, A. and Wang, X. and Husic, I. and Paki, K. and Hergeselle, M. and Vetter, B. and Hou, J. and Chen, W. and Wiebusch, L. and Meyer, I.M. and Wolff, T. and Selbach, M.
bioRxiv : 438176. 8 October 2018

Mechanisms of targeting the MDM2-p53-FOXM1 axis in well-differentiated intestinal neuroendocrine tumors.
Briest, F. and Grass, I. and Sedding, D. and Moebs, M. and Christen, F. and Benecke, J. and Fuchs, K. and Mende, S. and Kaemmerer, D. and Saenger, J. and Kunze, A. and Geisler, C. and Freitag, H. and Lewens, F. and Worpenberg, L. and Iwaszkiewicz, S. and Siegmund, B. and Walther, W. and Hummel, M. and Grabowski, P.
Neuroendocrinology 107 (1): 1-23. July 2018

Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial.
Burock, S. and Daum, S. and Keilholz, U. and Neumann, K. and Walther, W. and Stein, U.
BMC Cancer 18 (1): 297. 15 March 2018

The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.
Bégay, V. and Baumeier, C. and Zimmermann, K. and Heuser, A. and Leutz, A.
Scientific Reports 8 (1): 8417. 30 May 2018

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types.
Calabrese, C. and Davidson, N.R. and Fonseca, N.A. and He, Y. and Kahles, A. and Lehmann, K.V. and Liu, F. and Shiraishi, Y. and Soulette, C.M. and Urban, L. and Demircioğlu, D. and Greger, L. and Li, S. and Liu, D. and Perry, M.D. and Xiang, L. and Zhang, F. and Zhang, J. and Bailey, P. and Erkek, S. and Hoadley, K.A. and Hou, Y. and Kilpinen, H. and Korbel, J.O. and Marin, M.G. and Markowski, J. and Nandi, T. and Pan-Hammarström, Q. and Pedamallu, C.S. and Siebert, R. and Stark, S.G. and Su, H. and Tan, P. and Waszak, S.M. and Yung, C. and Zhu, S. and Awadalla, P. and Creighton, C.J. and Meyerson, M. and Ouellette, B.F.F. and Wu, K. and Yang, H. and Brazma, A. and Brooks, A.N. and Göke, J. and Rätsch, G. and Schwarz, R.F. and Stegle, O. and Zhang, Z.
bioRxiv : 183889. 12 March 2018

Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
Choi, I.K. and Wang, Z. and Ke, Q. and Hong, M. and Qian, Y. and Zhao, X. and Liu, Y. and Kim, H.J. and Ritz, J. and Cantor, H. and Rajewsky, K. and Wucherpfennig, K.W. and Zhang, B.
Proceedings of the National Academy of Sciences of the United States of America 115 (4): E686-E695. January 2018

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR.
Clauss, J. and Obenaus, M. and Miskey, C. and Ivics, Z. and Izsvák, Z. and Uckert, W. and Bunse, M.
Human Gene Therapy 29 (5): 569-584. May 2018

Genome-wide analysis of barrett's adenocarcinoma. a first step towards identifying patients at risk and developing therapeutic paths.
Dai, Y. and Wang, Q. and Gonzalez Lopez, A. and Anders, M. and Malfertheiner, P. and Vieth, M. and Kemmner, W.
Translational Oncology 11 (1): 116-124. February 2018

Randomized, phase 3 trial of inotuzumab ozogamicin plus rituximab versus chemotherapy plus rituximab for relapsed/refractory aggressive B-cell non-Hodgkin lymphoma.
Dang, N.H. and Ogura, M. and Castaigne, S. and Fayad, L.E. and Jerkeman, M. and Radford, J. and Pezzutto, A. and Bondarenko, I. and Stewart, D.A. and Shnaidman, M. and Sullivan, S. and Vandendries, E. and Tobinai, K. and Ramchandren, R. and Hamlin, P.A. and Giné, E. and Ando, K.
British Journal of Haematology 182 (4): 583-586. August 2018

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V. and Rosen, D.B. and Wang, Q. and Gazumyan, A. and Pai, J.A. and Oliveira, T.Y. and Sundaravinayagam, D. and Zhang, W. and Andreani, M. and Keller, L. and Kieffer-Kwon, K.R. and Pękowska, A. and Jung, S. and Driesner, M. and Subbotin, R.I. and Casellas, R. and Chait, B.T. and Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72 (4): 636-649. 15 November 2018

Stage-specific metabolic features of differentiating neurons: implications for toxicant sensitivity.
Delp, J. and Gutbier, S. and Cerff, M. and Zasada, C. and Niedenführ, S. and Zhao, L. and Smirnova, L. and Hartung, T. and Borlinghaus, H. and Schreiber, F. and Bergemann, J. and Gätgens, J. and Beyss, M. and Azzouzi, S. and Waldmann, T. and Kempa, S. and Nöh, K. and Leist, M.
Toxicology and Applied Pharmacology 354 : 64-80. 1 September 2018

Structural changes of TasA in biofilm formation of Bacillus subtilis.
Diehl, A. and Roske, Y. and Ball, L. and Chowdhury, A. and Hiller, M. and Molière, N. and Kramer, R. and Stöppler, D. and Worth, C.L. and Schlegel, B. and Leidert, M. and Cremer, N. and Erdmann, N. and Lopez, D. and Stephanowitz, H. and Krause, E. and van Rossum, B.J. and Schmieder, P. and Heinemann, U. and Turgay, K. and Akbey, Ü. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 115 (13): 3237-3242. 27 March 2018

omniCLIP: probabilistic identification of protein-RNA interactions from CLIP-seq data.
Drewe-Boss, P. and Wessels, H.H. and Ohler, U.
Genome Biology 19 : 183. 1 November 2018

Spatial transcriptomics of C. elegans males and hermaphrodites identifies novel fertility genes.
Ebbing, A. and Vertesy, A. and Betist, M. and Spanjaard, B. and Junker, J.P. and van Oudenaarden, A. and Berezikov, E. and Korswagen, H.
bioRxiv : 348201. 15 June 2018

Spatial transcriptomics of C. elegans males and hermaphrodites identifies sex-specific differences in gene expression patterns.
Ebbing, A. and Vértesy, Á. and Betist, M.C. and Spanjaard, B. and Junker, J.P. and Berezikov, E. and van Oudenaarden, A. and Korswagen, H.C.
Developmental Cell 8 November 2018 (In Press)

Struktur und Funktion des mechanochemischen Motorproteins Dynamin.
Faelber, K. and Daumke, O.
BIOspektrum 24 (5): 481-483. September 2018

A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit via FRET in a binary system.
Fang, G.M. and Chamiolo, J. and Kankowski, S. and Hövelmann, F. and Friedrich, D. and Löwer, A. and Meier, J.C. and Seitz, O.
Chemical Science 9 (21): 4794-4800. 7 June 2018

Keratinocyte-specific ablation of protease-activated receptor-2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease.
Francis, N. and Ayodele, B.A. and O'Brien-Simpson, N.M. and Birchmeier, W. and Pike, R.N. and Pagel, C.N. and Mackie, E.J.
Cellular Microbiology 20 (11): e12891. November 2018

Circular RNAs: a new class of biomarkers as a rising interest in laboratory medicine.
Franz, A. and Rabien, A. and Stephan, C. and Ralla, B. and Fuchs, S. and Jung, K. and Fendler, A.
Clinical Chemistry and Laboratory Medicine 56 (12): 1992-2003. December 2018

Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Fritsche-Guenther, R. and Zasada, C. and Mastrobuoni, G. and Royla, N. and Rainer, R. and Roßner, F. and Pietzke, M. and Klipp, E. and Sers, C. and Kempa, S.
Scientific Reports 8 (1): 9204. 15 June 2018

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells.
Gabryšová, L. and Alvarez-Martinez, M. and Luisier, R. and Cox, L.S. and Sodenkamp, J. and Hosking, C. and Pérez-Mazliah, D. and Whicher, C. and Kannan, Y. and Potempa, K. and Wu, X. and Bhaw, L. and Wende, H. and Sieweke, M.H. and Elgar, G. and Wilson, M. and Briscoe, J. and Metzis, V. and Langhorne, J. and Luscombe, N.M. and O'Garra, A.
Nature Immunology 19 (5): 497-507. May 2018

A novel form of RNA double helix based on G·U and C·A(+) wobble base pairing.
Garg, A. and Heinemann, U.
RNA 24 (2): 209-218. February 2018

Next-Generation in vivo modeling of human cancers.
Gargiulo, G.
Frontiers in Oncology 8 : 429. October 2018

Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.
Gavvovidis, I. and Leisegang, M. and Willimsky, G. and Miller, N.J. and Nghiem, P. and Blankenstein, T.
Clinical Cancer Research 24 (15): 3644-3655. August 2018

Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.
Graf, L. and Dick, A. and Sendker, F. and Barth, E. and Marz, M. and Daumke, O. and Kochs, G.
Journal of Biological Chemistry 293 (9): 3056-3072. 2 March 2018

Developmental and functional heterogeneity of monocytes.
Guilliams, M. and Mildner, A. and Yona, S.
Immunity 49 (4): 595-613. 16 October 2018

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.
Hammer, Q. and Rückert, T. and Borst, E.M. and Dunst, J. and Haubner, A. and Durek, P. and Heinrich, F. and Gasparoni, G. and Babic, M. and Tomic, A. and Pietra, G. and Nienen, M. and Blau, I.W. and Hofmann, J. and Na, I.K. and Prinz, I. and Koenecke, C. and Hemmati, P. and Babel, N. and Arnold, R. and Walter, J. and Thurley, K. and Mashreghi, M.F. and Messerle, M. and Romagnani, C.
Nature Immunology 19 (5): 453-463. May 2018

Expanding the map of protein-RNA interaction sites via cell fusion followed by PAR-CLIP.
Hinze, F. and Drewe-Boss, P. and Milek, M. and Ohler, U. and Landthaler, M. and Gotthardt, M.
RNA Biology 15 (3): 359-368. 4 March 2018

Unraveling the transcriptional regulation of TWIST1 in limb development.
Hirsch, N. and Eshel, R. and Bar Yaacov, R. and Shahar, T. and Shmulevich, F. and Dahan, I. and Levaot, N. and Kaplan, T. and Lupiáñez, D.G. and Birnbaum, R..
PLoS Genetics 14 (10): e1007738. 29 October 2018

Nontargeted identification of tracer incorporation in high-resolution mass spectrometry.
Hoffmann, F. and Jaeger, C. and Bhattacharya, A. and Schmitt, C.A. and Lisec, J.
Analytical Chemistry 90 (12): 7253-7260. 19 June 2018

Efficient non-viral gene delivery into human hematopoietic stem cells by minicircle Sleeping Beauty transposon vectors.
Holstein, M. and Mesa-Nuñez, C. and Miskey, C. and Almarza, E. and Poletti, V. and Schmeer, M. and Grueso, E. and Ordóñez Flores, J.C. and Kobelt, D. and Walther, W. and Aneja, M.K. and Geiger, J, and Bonig, H.B. and Izsvák, Z. and Schleef, M. and Rudolph, C. and Mavilio, F. and Bueren, J.A. and Guenechea, G. and Ivics, Z.
Molecular Therapy 26 (4): 1137-1153. 4 April 2018

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D. and Schön, C. and Loddenkemper, C. and Lohneis, P. and Kühl, A.A. and Sommermann, T. and Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

Genetics of intellectual disability in consanguineous families.
Hu, H. and Kahrizi, K. and Musante, L. and Fattahi, Z. and Herwig, R. and Hosseini, M. and Oppitz, C. and Abedini, S.S. and Suckow, V. and Larti, F. and Beheshtian, M. and Lipkowitz, B. and Akhtarkhavari, T. and Mehvari, S. and Otto, S. and Mohseni, M. and Arzhangi, S. and Jamali, P. and Mojahedi, F. and Taghdiri, M. and Papari, E. and Soltani Banavandi, M.J. and Akbari, S. and Tonekaboni, S.H. and Dehghani, H. and Ebrahimpour, M.R. and Bader, I. and Davarnia, B. and Cohen, M. and Khodaei, H. and Albrecht, B. and Azimi, S. and Zirn, B. and Bastami, M. and Wieczorek, D. and Bahrami, G. and Keleman, K. and Vahid, L.N. and Tzschach, A. and Gärtner, J. and Gillessen-Kaesbach, G. and Varaghchi, J.R. and Timmermann, B. and Pourfatemi, F. and Jankhah, A. and Chen, W. and Nikuei, P. and Kalscheuer, V.M. and Oladnabi, M. and Wienker, T.F. and Ropers, H.H. and Najmabadi, H.
Molecular Psychiatry 4 January 2018 (In Press)

Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
Nature Communications 9 (1): 4472. 26 October 2018

Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during mitosis.
Imami, K. and Milek, M. and Bogdanow, B. and Yasuda, T. and Kastelic, N. and Zauber, H. and Ishihama, Y. and Landthaler, M. and Selbach, M.
Molecular Cell 72 (1): 84-98. 4 October 2018

Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: a comprehensive examination of the potential carriers for semiochemicals.
Iovinella, I. and McAfee, A. and Mastrobuoni, G. and Kempa, S. and Foster, L.J. and Pelosi, P. and Dani, F.R.
Journal of Proteomics 181 : 131-141. 15 June 2018

Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: a comprehensive examination of the potential carriers for semiochemicals.
Iovinella, I. and McAfee, A. and Mastrobuoni, G. and Kempa, S. and Foster, L.J. and Pelosi, P. and Dani, F.R.
bioRxiv : 260539. 7 February 2018

Long noncoding RNA lISPR1 is required for S1P signaling and endothelial cell function.
Josipovic, I. and Pflueger, B. and Fork, C. and Vasconez, A.E. and Oo, J.A. and Hitzel, J. and Seredinski, S. and Gamen, E. and Heringdorf, D.M.Z. and Chen, W. and Looso, M. and Pullamsetti, S.S. and Brandes, R.P. and Leisegang, M.S.
Journal of Molecular and Cellular Cardiology 116 : 57-68. March 2018

Crystal structures of the single PDZ domains from GRASP65 and their interaction with the golgin GM130.
Jurk, C.M. and Roske, Y. and Heinemann, U.
Croatica Chemica Acta 91 (2): 255-264. June 2018

Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.
Kabrani, E. and Chu, V.T. and Tasouri, E. and Sommermann, T. and Baßler, K. and Ulas, T. and Zenz, T. and Bullinger, L. and Schultze, J. and Rajewsky, K. and Sander, S.
Blood 17 October 2018 (In Press)

Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets via protocol-specific bias modeling.
Karabacak Calviello, A. and Hirsekorn, A. and Wurmus, R. and Yusuf, D. and Ohler, U.
bioRxiv : 284364. 19 March 2018

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M. and Wende, H. and Walcher, J. and Kühnemund, J. and Cheret, C. and Kempa, S. and McShane, E. and Selbach, M. and Lewin, G.R. and Birchmeier, C.
Genes & Development 32 (9-10): 645-657. 10 May 2018

S1P signalling differentially affects migration of peritoneal B cell populations in vitro and influences the production of intestinal IgA in vivo.
Kleinwort, A. and Luehrs, F. and Heidecke, C.D. and Lipp, M. and Schulze, T.
International Journal of Molecular Sciences 19 (2): 391. 29 January 2018

Structural investigation of glycan recognition by the ERAD quality control lectin Yos9.
Kniss, A. and Kazemi, S. and Löhr, F. and Berger, M. and Rogov, V.V. and Güntert, P. and Sommer, T. and Jarosch, E. and Dötsch, V.
Journal of Biomolecular NMR 72 (1-2): 1-10. October 2018

Chain assembly and disassembly processes differently affect the conformational space of ubiquitin chains.
Kniss, A. and Schuetz, D. and Kazemi, S. and Pluska, L. and Spindler, P.E. and Rogov, V.V. and Husnjak, K. and Dikic, I. and Güntert, P. and Sommer, T. and Prisner, T.F. and Dötsch, V.
Structure 26 (2): 249-258. 6 February 2018

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. and Ofenbauer, A. and Bulut, S.I. and Uyar, B. and Baytek, G. and Sommermeier, A. and Seelk, S. and He, M. and Hirsekorn, A. and Vucicevic, D. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis.
Kragesteen, B.K. and Spielmann, M. and Paliou, C. and Heinrich, V. and Schöpflin, R. and Esposito, A. and Annunziatella, C. and Bianco, S. and Chiariello, A.M. and Jerković, I. and Harabula, I. and Guckelberger, P. and Pechstein, M. and Wittler, L. and Chan, Wi.L. and Franke, M. and Lupiáñez, D.G. and Kraft, K. and Timmermann, B. and Vingron, M. and Visel, A. and Nicodemi, M. and Mundlos, S. and Andrey, G.
Nature Genetics 50 (10): 1463-1473. October 2018

Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas.
Kratzsch, T. and Kuhn, S.A. and Joedicke, A. and Hanisch, U.K. and Vajkoczy, P. and Hoffmann, J. and Fichtner, I.
Journal of Cancer Research and Clinical Oncology 144 (5): 809-819. May 2018

NF-κB participates in mouse hair cycle control and plays distinct roles in the various pelage hair follicle types.
Krieger, K. and Millar, S.E. and Mikuda, N. and Krahn, I. and Kloepper, J.E. and Bertolini, M. and Scheidereit, C. and Paus, R. and Schmidt-Ullrich, R.
Journal of Investigative Dermatology 138 (2): 256-264. February 2018

Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G. and Uhlemann, R. and Richter, N. and Klempin, F. and Wegner, S. and Staerck, L. and Wolf, S. and Uckert, W. and Kettenmann, H. and Endres, M. and Gertz, K.
Acta Neuropathologica 135 (4): 551. April 2018

Solvent networks tune thermodynamics of oligosaccharide complex formation in an extended protein binding site.
Kunstmann, S. and Gohlke, U. and Broeker, N.K. and Roske, Y. and Heinemann, U. and Santer, M. and Barbirz, S.
Journal of the American Chemical Society 140 (33): 10447-10455. 22 August 2018

Redundant regulation.
Lacadie, S.A. and Ohler, U.
Nature Ecology & Evolution 2 (3): 418-419. March 2018

Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates.
Langer, H.T. and Senden, J.M.G. and Gijsen, A.P. and Kempa, S. and van Loon, Luc J. C. and Spuler, S.
Frontiers in Physiology 9 : 1220. August 2018

Mapping the MHC class I spliced immunopeptidome of cancer cells.
Liepe, J. and Sidney, J. and Lorenz, F.K.M. and Sette, A. and Mishto, M.
Cancer Immunology Research 13 November 2018 (In Press)

Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill.
Lin, X. and Noel, J.K. and Wang, Q. and Ma, J. and Onuchic, J.N.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): E7905-E7913. 21 August 2018

Structural basis for membrane tethering by a bacterial dynamin-like pair.
Liu, J. and Noel, J.K. and Low, H.H.
Nature Communications 9 (1): 3345. 21 August 2018

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.
Löber, U. and Hobbs, M. and Dayaram, A. and Tsangaras, K. and Jones, K. and Alquezar-Planas, D.E. and Ishida, Y. and Meers, J. and Mayer, J. and Quedenau, C. and Chen, W. and Johnson, R.N. and Timms, P. and Young, P.R. and Roca, A.L. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): 8609-8614. 21 August 2018

An integrated understanding of the molecular mechanisms how adipose tissue metabolism affects long-term body weight maintenance.
Mai, K. and Li, L. and Wiegand, S. and Brachs, M. and Leupelt, V. and Ernert, A. and Kühnen, P. and Hübner, N. and Robinson, P. and Chen, W. and Krude, H. and Spranger, J.
Diabetes 2 November 2018 (In Press)

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. and Kirchner, M. and Uyar, B. and Cheng, J.Y. and Russo, G. and Hernandez-Miranda, L.R. and Szymborska, A. and Zauber, H. and Rudolph, I.M. and Willnow, T.E. and Akalin, A. and Haucke, V. and Gerhardt, H. and Birchmeier, C. and Kühn, R. and Krauss, M. and Diecke, S. and Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N. and Kolesnichenko, M. and Beaudette, P. and Popp, O. and Uyar, B. and Sun, W. and Tufan, A.B. and Perder, B. and Akalin, A. and Chen, W. and Mertins, P. and Dittmar, G. and Hinz, M. and Scheidereit, C.
EMBO Journal 22 November 2018 (In Press)

Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M. and Fan, D.N.Y. and Belenki, D. and Däbritz, J.H.M. and Zhao, Z. and Yu, Y. and Dörr, J.R. and Dimitrova, L. and Lenze, D. and Monteiro Barbosa, I.A. and Mendoza-Parra, M.A. and Kanashova, T. and Metzner, M. and Pardon, K. and Reimann, M. and Trumpp, A. and Dörken, B. and Zuber, J. and Gronemeyer, H. and Hummel, M. and Dittmar, G. and Lee, S. and Schmitt, C.A.
Nature 553 (7686): 96-100. 4 January 2018

The Senescence-Stemness Alliance - a cancer-hijacked regeneration principle.
Milanovic, M. and Yu, Y. and Schmitt, C.A.
Trends in Cell Biology 28 (12): 1049-1061. December 2018

Systematic detection of poly(A)(+) RNA-interacting proteins and their differential binding.
Milek, M. and Landthaler, M.
Methods in Molecular Biology 1649 : 405-417. 2018

Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Ming, Q. and Roske, Y. and Schuetz, A. and Walentin, K. and Ibraimi, I. and Schmidt-Ott, K.M. and Heinemann, U.
Nucleic Acids Research 46 (4): 2082-2095. 28 February 2018

Testicular macrophages: guardians of fertility.
Mossadegh-Keller, Noushin and Sieweke, M.H.
Cellular Immunology 330 : 120-125. August 2018

Deciphering human ribonucleoprotein regulatory networks.
Mukherjee, N. and Wessels, H.H. and Lebedeva, S. and Sajek, M. and Ghanbari, M. and Garzia, A. and Munteanu, A. and Farazi, T. and Hoell, J.I. and Akat, K. and Tuschl, T. and Ohler, U.
bioRxiv : 295097. 10 April 2018

Deciphering human ribonucleoprotein regulatory networks.
Mukherjee, N. and Wessels, H.H. and Lebedeva, S. and Sajek, M. and Ghanbari, M. and Garzia, A. and Munteanu, A. and Yusuf, D. and Farazi, T. and Hoell, J.I. and Akat, K.M. and Akalin, A. and Tuschl, T. and Ohler, U.
Nucleic Acids Research 5 December 2018 (In Press)

SSMART: Sequence-structure motif identification for RNA-binding proteins.
Munteanu, A. and Mukherjee, N. and Ohler, U.
Bioinformatics 34 (23): 3990-3998. 1 December 2018

SSMART: Sequence-structure motif identification for RNA-binding proteins.
Munteanu, A. and Mukherjee, N. and Ohler, U.
bioRxiv : 287953. 23 March 2018

Pan-class I  PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.
Müller, A. and Gillissen, B. and Richter, A. and Richter, A. and Chumduri, C. and Daniel, P.T. and Scholz, C.W.
Cell Death & Disease 9 (3): 384. 7 March 2018

Systematic characterization of RhoGEF/RhoGAP regulatory proteins reveals organization principles of Rho GTPase signaling.
Müller, P.M. and Rademacher, J. and Bagshaw, R.D. and Alp, K.M. and Giudice, G. and Heinrich, L.E. and Barth, C. and Eccles, R.L. and Sanchez-Castro, M. and Brandenburg, L. and Mbamalu, G. and Tucholska, M. and Spatt, L. and Wortmann, C. and Czajkowski, M.T. and Welke, R.W. and Zhang, S. and Nguyen, V. and Rrustemi, T. and Trnka, P. and Freitag, K. and Larsen, B. and Popp, O. and Mertins, P. and Bakal, C. and Gingras, A.C. and Pertz, O. and Roth, F.P. and Colwill, K. and Pawson, T. and Petsalaki, E. and Rocks, O.
bioRxiv : 354316. 25 June 2018

Finding RNA structure in the unstructured RBPome.
Orenstein, Y. and Ohler, U. and Berger, B.
BMC Genomics 19 (1): 154. 20 February 2018

Evolutionary plasticity in the innate immune function of Akirin.
Polanowska, J. and Chen, J.X. and Soulé, J. and Omi, S. and Belougne, J. and Taffoni, C. and Pujol, N. and Selbach, M. and Zugasti, O. and Ewbank, J.J.
PLoS Genetics 14 (7): e1007494. 23 July 2018

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.
Poncette, L. and Chen, X. and Lorenz, F.K.M. and Blankenstein, T.
Journal of Clinical Investigation 10 December 2018 (In Press)

KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells.
Qi, X.T. and Li, Y.L. and Zhang, Y.Q. and Xu, T. and Lu, B. and Fang, L. and Gao, J.Q. and Yu, L.S. and Zhu, D.F. and Yang, B. and He, Q.J. and Ying, M.D.
Acta Pharmacologica Sinica 21 June 2018 (In Press)

Ectopic transplastomic expression of a synthetic MatK gene leads to cotyledon-specific leaf variegation.
Qu, Y. and Legen, J. and Arndt, J. and Henkel, S. and Hoppe, G. and Thieme, C. and Ranzini, G. and Muino, J.M. and Weihe, A. and Ohler, U. and Weber, G. and Ostersetzer, O. and Schmitz-Linneweber, C.
Frontiers in Plant Science 9 : 1453. October 2018

Kinase-controlled phase transition of membraneless organelles in mitosis.
Rai, A.K. and Chen, J.X. and Selbach, M. and Pelkmans, L.
Nature 559 (7713): 211-216. July 2018

miR-9-5p in nephrectomy specimens is a potential predictor of primary resistance to first-line treatment with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma.
Ralla, B. and Busch, J. and Flörcken, A. and Westermann, J. and Zhao, Z. and Kilic, E. and Weickmann, S. and Jung, M. and Fendler, A. and Jung, K.
Cancers 10 (9): 321. 10 September 2018

Postnatal DNA demethylation and its role in tissue maturation.
Reizel, Y. and Sabag, O. and Skversky, Y. and Spiro, A. and Steinberg, B. and Bernstein, D. and Wang, A. and Kieckhaefer, J. and Li, C. and Pikarsky, E. and Levin-Klein, R. and Goren, A. and Rajewsky, K. and Kaestner, K.H. and Cedar, H.
Nature Communications 9 (1): 2040. 23 May 2018

Quantifying multi-layered expression regulation in response to stress of the endoplasmic reticulum.
Rendleman, J. and Cheng, Z. and Maity, S. and Kastelic, N. and Munschauer, M. and Allgoewer, K. and Teo, G. and Zhang, Y.B. and Lei, A. and Parker, B. and Landthaler, M. and Freeberg, L. and Kuersten, S. and Choi, H. and Vogel, C.
bioRxiv : 308379. 25 April 2018

New insights into the cellular temporal response to proteostatic stress.
Rendleman, J. and Cheng, Z. and Maity, S. and Kastelic, N. and Munschauer, M. and Allgoewer, K. and Teo, G. and Zhang, Y.B.M. and Lei, A. and Parker, B. and Landthaler, M. and Freeberg, L. and Kuersten, S. and Choi, H. and Vogel, C.
eLife 7 : e39054. 12 October 2018

Confocal endomicroscopy in diagnosis of intestinal chronic graft-versus-host disease.
Rieger, K. and Günther, U. and Erben, U. and Kühl, A. and Loddenkemper, C. and Pezzutto, A. and Siegmund, B. and Bojarski, C.
Hematological Oncology 36 (1): 291-298. February 2018

Non-canonical HIF-1 stabilization is essential for intestinal tumorigenesis.
Rohwer, N. and Jumpertz, S. and Erdem, M. and Egners, A. and Warzecha, K.T. and Fragoulis, A. and Kuehl, A.A. and Kramann, R. and Neuss, S. and Rudolph, I. and Endermann, T. and Zasada, C. and Apostolova, I. and Gerling, M. and Kempa, S. and Hughes, R. and Lewis, C.E. and Brenner, W. and Malinowski, M.B. and Stockmann, M. and Schomburg, L. and Faller, W. and Sansom, O.J. and Tacke, F. and Morkel, M. and Cramer, T.
bioRxiv : 273045. 28 February 2018

Shp-2 is dispensable for establishing T cell exhaustion and for PD-1 signaling in vivo.
Rota, G. and Niogret, C. and Dang, A.T. and Barros, C.R. and Fonta, N.P. and Alfei, F. and Morgado, L. and Zehn, D. and Birchmeier, W. and Vivier, E. and Guarda, G.
Cell Reports 23 (1): 39-49. 3 April 2018

Combined human genome-wide RNAi and metabolite analyses identify IMPDH as a host-directed target against Chlamydia infection.
Rother, M. and Gonzalez, E. and Teixeira da Costa, A.R. and Wask, L. and Gravenstein, I. and Pardo, M. and Pietzke, M. and Gurumurthy, R.K. and Angermann, J. and Laudeley, R. and Glage, S. and Meyer, M. and Chumduri, C. and Kempa, S. and Dinkel, K. and Unger, A. and Klebl, B. and Klos, A. and Meyer, T.F.
Cell Host & Microbe 23 (5): 661-671. 9 May 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
Rozman, J. and Rathkolb, B. and Oestereicher, M.A. and Schütt, C. and Ravindranath, A.C. and Leuchtenberger, S. and Sharma, S. and Kistler, M. and Willershäuser, M. and Brommage, R. and Meehan, T.F. and Mason, J. and Haselimashhadi, H. and Hough, T. and Mallon, A.M. and Wells, S. and Santos, L. and Lelliott, C.J. and White, J.K. and Sorg, T. and Champy, M.F. and Bower, L.R. and Reynolds, C. L. and Flenniken, A.M. and Murray, St.A. and Nutter, L.M.J. and Svenson, K.L. and West, D. and Tocchini-Valentini, G.P. and Beaudet, A.L. and Bosch, F. and Braun, R.B. and Dobbie, M.S. and Gao, X. and Herault, Y. and Moshiri, A. and Moore, B.A. and Kent Lloyd, K.C. and McKerlie, C. and Masuya, H. and Tanaka, N. and Flicek, P. and Parkinson, H.E. and Sedlacek, R. and Seong, J.K. and Wang, C.K.L. and Moore, M. and Brown, S.D. and Tschöp, M.H. and Wurst, W. and Klingenspor, M. and Wolf, E. and Beckers, J. and Machicao, F. and Peter, A. and Staiger, H. and Häring, H.U. and Grallert, H. and Campillos, M. and Maier, H. and Fuchs, H. and Gailus-Durner, V. and Werner, T. and Hrabe de Angelis, M.
Nature Communications 9 (1): 288. 18 January 2018

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Ruess, D.A. and Heynen, G.J. and Ciecielski, K.J. and Ai, J. and Berninger, A. and Kabacaoglu, D. and Görgülü, K. and Dantes, Z. and Wörmann, S.M. and Diakopoulos, K.N. and Karpathaki, A.F. and Kowalska, M. and Kaya-Aksoy, E. and Song, L. and Zeeuw van der Laan, E.A. and López-Alberca, M.P. and Nazaré, M. and Reichert, M. and Saur, D. and Erkan, M.M. and Hopt, U.T. and Sainz, B. and Birchmeier, W. and Schmid, R.M. and Lesina, M. and Algül, H.
Nature Medicine 24 (7): 954-960. July 2018

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Schleussner, N. and Merkel, O. and Costanza, M. and Liang, H.C. and Hummel, F. and Romagnani, C. and Durek, P. and Anagnostopoulos, I. and Hummel, M. and Jöhrens, K. and Niedobitek, A. and Griffin, P.R. and Piva, R. and Sczakiel, H.L. and Woessmann, W. and Damm-Welk, C. and Hinze, C. and Stoiber, D. and Gillissen, B. and Turner, S.D. and Kaergel, E. and von Hoff, L. and Grau, M. and Lenz, G. and Dörken, B. and Scheidereit, C. and Kenner, L. and Janz, M. and Mathas, S.
Leukemia 32 (9): 1994-2007. September 2018

Regulation of the natriuretic peptide receptor 2 (Npr2) by phosphorylation of juxtamembrane serine and threonine residues is essential for bifurcation of sensory axons.
Schmidt, H. and Dickey, D.M. and Dumoulin, A. and Octave, M. and Robinson, J.W. and Kühn, R. and Feil, R. and Potter, L.R. and Rathjen, F.G.
Journal of Neuroscience 38 (45): 9768-9780. 7 November 2018

ERAP1-dependent antigen cross-presentation determines efficacy of adoptive T cell therapy in mice.
Schmidt, K. and Keller, C. and Kühl, A.A. and Textor, A. and Seifert, U. and Blankenstein, T. and Willimsky, G. and Kloetzel, P.M.
Cancer Research 78 (12): 3243-3254. June 2018

UnSASPing senescence: unmasking tumor suppression?
Schmitt, C.A.
Cancer Cell 34 (1): 6-8. 9 July 2018

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
Schrade, K. and Tröger, J. and Eldahshan, A. and Zühlke, K. and Abdul Azeez, K.R. and Elkins, J.M. and Neuenschwander, M. and Oder, A. and Elkewedi, M.M.H. and Jaksch, S. and Andrae, K. and Li, J. and Fernandes, J. and Müller, P.M. and Grunwald, S. and Marino, S.F. and Vukićević, T. and Eichhorst, J. and Wiesner, B. and Weber, M. and Kapiloff, M. and Rocks, O. and Daumke, O. and Wieland, T. and Knapp, S. and von Kries, J.P. and Klussmann, E.
PLoS ONE 13 (1): e0191423. 26 January 2018

Loss-of-function uORF mutations in human malignancies.
Schulz, J. and Mah, N. and Neuenschwander, M. and Kischka, T. and Ratei, R. and Schlag, P.M. and Castaños-Vélez, E. and Fichtner, I. and Tunn, P.U. and Denkert, C. and Klaas, O. and Berdel, W.E. and von Kries, J.P. and Makalowski, W. and Andrade-Navarro, M.A. and Leutz, A. and Wethmar, K.
Scientific Reports 8 (1): 2395. 5 February 2018

Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Serresi, M. and Siteur, B. and Hulsman, D. and Company, C. and Schmitt, M.J. and Lieftink, C. and Morris, B. and Cesaroni, M. and Proost, N. and Beijersbergen, R.L. and van Lohuizen, M. and Gargiulo, G.
Journal of Experimental Medicine 215 (12): 3115. 3 December 2018

Simultaneous lineage tracing and cell-type identification using CRISPR-Cas9-induced genetic scars.
Spanjaard, B. and Hu, B. and Mitic, N. and Olivares-Chauvet, P. and Janjuha, S. and Ninov, N. and Junker, J.P.
Nature Biotechnology 36 (5): 469-473. May 2018

Structural variation in the 3D genome.
Spielmann, M. and Lupiáñez, D.G. and Mundlos, S.
Nature Reviews Genetics 19 (7): 453-467. July 2018

Deciphering the universe of RNA structures and trans RNA-RNA interactions of transcriptomes in vivo: from experimental protocols to computational analyses.
Stefanov, S.R. and Meyer, I.M.
In: Systems Biology. RNA Technologies . Springer, Cham, 173-216. ISBN 978-3-319-92966-8 2018

Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels.
Strasen, J. and Sarma, U. and Jentsch, M. and Bohn, S. and Sheng, C. and Horbelt, D. and Knaus, P. and Legewie, S. and Loewer, A.
Molecular Systems Biology 14 (1): e7733. 25 January 2018

Metabolic labeling of newly synthesized RNA with 4sU to in parallel assess RNA transcription and decay.
Sun, W. and Chen, W.
Methods in Molecular Biology 1720 : 25-34. 2018

Pervasive allele-specific regulation on RNA decay in hybrid mice.
Sun, W. and Gao, Q. and Schaefke, B. and Hu, Y. and Chen, W.
Life Science Alliance 1 (2): e201800052. May 2018

A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo.
Szyska, M. and Herda, S. and Althoff, S. and Heimann, A. and Russ, J. and D'Abundo, D. and Dang, T.M. and Durieux, I. and Dörken, B. and Blankenstein, T. and Na, I.K.
Cancer Immunology Research 6 (1): 110-120. January 2018

Evaluating uncertainty in signaling networks using logical modeling.
Thobe, K. and Kuznia, C. and Sers, C. and Siebert, H.
Frontiers in Physiology 9 : 1335. October 2018

MYCN-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma.
Tjaden, B. and Baum, K. and Marquardt, V. and Simon, M. and Trajkovic-Arsic, M. and Kouril, T. and Siebers, B. and Lisec, J. and Siveke, J.T. and Schulte, J.H. and Benary, U. and Remke, M. and Wolf, J. and Schramm, A.
bioRxiv : 423756. 25 September 2018

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal.
Turajlic, S. and Xu, H. and Litchfield, K. and Rowan, A. and Horswell, S. and Chambers, T. and O'Brien, T. and Lopez, J.I. and Watkins, T.B.K. and Nicol, D. and Stares, M. and Challacombe, B. and Hazell, S. and Chandra, A. and Mitchell, T.J. and Au, L. and Eichler-Jonsson, C. and Jabbar, F. and Soultati, A. and Chowdhury, S. and Rudman, S. and Lynch, J. and Fernando, A. and Stamp, G. and Nye, E. and Stewart, A. and Xing, W. and Smith, J.C. and Escudero, M. and Huffman, A. and Matthews, N. and Elgar, G. and Phillimore, B. and Costa, M. and Begum, S. and Ward, S. and Salm, M. and Boeing, S. and Fisher, R. and Spain, L. and Navas, C. and Grönroos, E. and Hobor, S. and Sharma, S. and Aurangzeb, I. and Lall, S. and Polson, A. and Varia, M. and Horsfield, C. and Fotiadis, N. and Pickering, L. and Schwarz, R.F. and Silva, B. and Herrero, J. and Luscombe, N.M. and Jamal-Hanjani, M. and Rosenthal, R. and Birkbak, N.J. and Wilson, G.A. and Pipek, O. and Ribli, D. and Krzystanek, M. and Csabai, I. and Szallasi, Z. and Gore, M. and McGranahan, N. and Van Loo, P. and Campbell, P. and Larkin, J. and Swanton, C.
Cell 173 (3): 595-610. 19 April 2018

Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta, E.C. and Vieira-Vieira, C.H. and Hick, T. and Wessels, H.H. and Figini, D. and Moschall, R. and Medenbach, J. and Ohler, U. and Granneman, S. and Selbach, M. and Beckmann, B.M.
bioRxiv : 333385. 30 May 2018

Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury.
Van Steenwinckel, J. and Schang, A.L. and Krishnan, M.L. and Degos, V. and Delahaye-Duriez, A. and Bokobza, C. and Verdonk, F. and Montane, A. and Sigaut, S. and Hennebert, O. and Lebon, S. and Schwendimann, L. and Le Charpentier, T. and Hassan-Abdi, R. and Ball, G. and Aljabar, P. and Saxena, A. and Holloway, R.K. and Birchmeier, W. and Miron, V. and Rowitch, D. and Chretien, F. and Leconte, C. and Besson, V.C. and Petretto, E.G. and Edwards, A.D. and Hagberg, H. and Soussi-Yanicostas, N. and Fleiss, B. and Gressens, P.
bioRxiv : 334359. 31 May 2018

Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury.
Vigolo, E. and Markó, L. and Hinze, C. and Müller, D.N. and Schmidt-Ullrich, R. and Schmidt-Ott, K.M.
Kidney International 15 November 2018 (In Press)

Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching.
Wagner, A.S. and Politi, A.Z. and Ast, A. and Bravo-Rodriguez, K. and Baum, K. and Buntru, A. and Strempel, N.U. and Brusendorf, L. and Hänig, C. and Boeddrich, A. and Plassmann, S. and Klockmeier, K. and Ramirez-Anguita, J.M. and Sanchez-Garcia, E. and Wolf, J. and Wanker, E.E.
Journal of Molecular Biology 430 (12): 1725-1744. 8 June 2018

Phylogenetic quantification of intratumor heterogeneity.
Watkins, T.B.K. and Schwarz, R.F.
Cold Spring Harbor Perspectives in Medicine 8 (4): a028316. April 2018

Oncogenic MYD88 mutations in lymphoma: novel insights and therapeutic possibilities.
Weber, A.N.R. and Cardona Gloria, Y. and Çınar, Ö. and Reinhardt, H.C. and Pezzutto, A. and Wolz, O.O.
Cancer Immunology Immunotherapy 67 (11): 1797-1807. November 2018

A novel allele for inducible Cre expression in germinal center B cells.
Weber, T. and Seagal, J. and Winkler, W. and Wirtz, T. and Chu, V.T. and Rajewsky, K.
European Journal of Immunology 25 October 2018 (In Press)

Ectopic expression of transcription factor BATF3 induces B-cell lymphomas in a murine B-cell transplantation model.
Weiser, C. and Petkova, M.V. and Rengstl, B. and Döring, C. and von Laer, D. and Hartmann, S. and Küppers, R. and Hansmann, M.L. and Newrzela, S.
Oncotarget 9 (22): 15942-15951. 23 March 2018

Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization.
Weng, Q. and Wang, J. and Wang, J. and Wang, J. and Sattar, F. and Zhang, Z. and Zheng, J. and Xu, Z. and Zhao, M. and Liu, X. and Yang, L. and Hao, G. and Fang, L. and Lu, Q.R. and Yang, B. and He, Q.
Cell Death & Disease 9 (2): 251. 14 February 2018

Global identification of functional microRNA::mRNA interactions in Drosophila.
Wessels, H.H. and Lebedeva, S. and Hirsekorn, A. and Mukherjee, N. and Ohler, U.
bioRxiv : 395335. 22 August 2018

Discovering novel hydrolases from hot environments.
Wohlgemuth, R. and Littlechild, J. and Monti, D. and Schnorr, K. and van Rossum, T. and Siebers, B. and Menzel, P. and Kublanov, I.V. and Rike, A.G. and Skretas, G. and Szabo, Z. and Peng, X. and Young, M.J.
Biotechnology Advances 36 (8): 2077-2100. December 2018

Cumulative regulatory potential of clustered methyl-arginine protein modifications.
Woodsmith, J. and Casado-Medrano, V. and Benlasfer, N. and Eccles, R. and Hutten, S. and Heine, C. and Thormann, V. and Abou-Ajram, C. and Rocks, O. and Dormann, D. and Stelzl, U.
bioRxiv : 289041. 26 March 2018

Interaction modulation through arrays of clustered methyl-arginine protein modifications.
Woodsmith, J. and Casado-Medrano, V. and Benlasfer, N. and Eccles, R.L. and Hutten, S. and Heine, C.L. and Thormann, V. and Abou-Ajram, C. and Rocks, O. and Dormann, D. and Stelzl, U.
Life Science Alliance 1 (5): e201800178. October 2018

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
Yang, J.Y. and Deng, X.Y. and Li, Y.S. and Ma, X.C. and Feng, J.X. and Yu, B. and Chen, Y. and Luo, Y.L. and Wang, X. and Chen, M.L. and Fang, Z.X. and Zheng, F.X. and Li, Y.P. and Zhong, Q. and Kang, T.B. and Song, L.B. and Xu, R.H. and Zeng, M.S. and Chen, W. and Zhang, H. and Xie, W. and Gao, S.
Nature Communications 9 (1): 1165. 21 March 2018

Good things come in threes.
Yona, S. and Mildner, A.
Science Immunology 3 (30): eaav5545. 7 December 2018

Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma.
Yu, Y. and Schleich, K. and Yue, B. and Ji, S. and Lohneis, P. and Kemper, K. and Silvis, M.S. and Qutob, N. and van Rooijen, E. and Werner-Klein, M. and Li, L. and Dhawan, D. and Meierjohann, S. and Reimann, M. and Elkahloun, A. and Treitschke, S. and Dörken, B. and Speck, C. and Mallette, F.A. and Zon, L.I. and Holmen, S.L. and Peeper, D.S. and Samuels, Y. and Schmitt, C.A. and Lee, S.
Cancer Cell 33 (2): 322-336. 12 February 2018

Picky: a simple online PRM and SRM method designer for targeted proteomics.
Zauber, H. and Kirchner, M. and Selbach, M.
Nature Methods 15 (3): 156-157. 28 February 2018

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender, A. and Huang, J. and Györfi, A.H. and Matei, A.E. and Trinh-Minh, T. and Xu, X. and Li, Y.N. and Chen, C.W. and Lin, J. and Dees, C. and Beyer, C. and Gelse, K. and Zhang, Z.Y. and Bergmann, C. and Ramming, A. and Birchmeier, W. and Distler, O. and Schett, G. and Distler, J.H.W.
Nature Communications 9 (1): 3259. 14 August 2018

Delayed allogeneic skin graft rejection in CD26-deficient mice.
Zhao, X. and Zhang, K. and Daniel, P. and Wisbrun, N. and Fuchs, H. and Fan, H.
Cellular and Molecular Immunology 23 March 2018 (In Press)

Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization of the molecular subtype.
Zinnall, U. and Weyerer, V. and Compérat, E. and Camparo, P. and Gaisa, N.T. and Knuechel-Clarke, R. and Perren, A. and Lugli, A. and Toma, M. and Baretton, G. and Kristiansen, G. and Wirtz, R.M. and Cheng, L. and Wullich, B. and Stoehr, R. and Hartmann, A. and Bertz, S.
Human Pathology 80 : 55-64. October 2018

2017

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution.
Abbosh, C. and Birkbak, N.J. and Wilson, G.A. and Jamal-Hanjani, M. and Constantin, T. and Salari, R. and Quesne, J.L. and Moore, D.A. and Veeriah, S. and Rosenthal, R. and Marafioti, T. and Kirkizlar, E. and Watkins, T.B.K. and McGranahan, N. and Ward, S. and Martinson, L. and Riley, J. and Fraioli, F. and Bakir, M.A. and Grönroos, E. and Zambrana, F. and Endozo, R. and Bi, W.L. and Fennessy, F.M. and Sponer, N. and Johnson, D. and Laycock, J. and Shafi, S. and Czyzewska-Khan, J. and Rowan, A. and Chambers, T. and Matthews, N. and Turajlic, S. and Hiley, C. and Lee, S.M. and Forster, M.D. and Ahmad, T. and Falzon, M. and Borg, E. and Lawrence, D. and Hayward, M. and Kolvekar, S. and Panagiotopoulos, N. and Janes, S.M. and Thakrar, R. and Ahmed, A. and Blackhall, F. and Summers, Y. and Hafez, D. and Naik, A. and Ganguly, A. and Kareht, S. and Shah, R. and Joseph, L. and Quinn, A.M. and Crosbie, P. and Naidu, B. and Middleton, G. and Langman, G. and Trotter, S. and Nicolson, M. and Remmen, H. and Kerr, K. and Chetty, M. and Gomersall, L. and Fennell, D.A. and Nakas, A. and Rathinam, S. and Anand, G. and Khan, S. and Russell, P. and Ezhil, V. and Ismail, B. and Irvin-Sellers, M. and Prakash, V. and Lester, J.F. and Kornaszewska, M. and Attanoos, R. and Adams, H. and Davies, H. and Oukrif, D. and Akarca, A.U. and Hartley, J.A. and Lowe, H.L. and Lock, S. and Iles, N. and Bell, H. and Ngai, Y. and Elgar, G. and Szallasi, Z. and Schwarz, R.F. and Herrero, J. and Stewart, A. and Quezada, S.A. and Van Loo, P. and Dive, C. and Lin, C.J. and Rabinowitz, M. and Aerts, H.J.W.L. and Hackshaw, A. and Shaw, J.A. and Zimmermann, B.G. and Swanton, C.
Nature 545 (7655): 446-451. 25 May 2017

Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A. and Xavier, A. and Abu Lubad, M. and Sigulla, J. and Kessler, M. and Hurwitz, R. and Meyer, T.F.
EBioMedicine 23 : 100-110. September 2017

The immune system prevents recurrence of transplanted but not autochthonous antigenic tumors after oncogene inactivation therapy.
Anders, K. and Kershaw, O. and Larue, L. and Gruber, A.D. and Blankenstein, T.
International Journal of Cancer 141 (12): 2551-2561. 15 December 2017

RNA-bioinformatics: tools, services and databases for the analysis of RNA-based regulation.
Backofen, R. and Engelhardt, J. and Erxleben, A. and Fallmann, J. and Grüning, B. and Ohler, U. and Rajewsky, N. and Stadler, P.F.
Journal of Biotechnology 261 : 76-84. 10 November 2017

Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis.
Baddack-Werncke, U. and Busch-Dienstfertig, M. and Gonzalez-Rodriguez, S. and Maddila, S.C. and Grobe, J. and Lipp, M. and Stein, C. and Mueller, G.
Journal of Neuroinflammation 14 (1): 30. 6 February 2017

Subsequent malignancies among long-term survivors of Hodgkin lymphoma and non-Hodgkin lymphoma: a pooled analysis of German cancer registry data (1990-2012).
Baras, N. and Dahm, S. and Haberland, J. and Janz, M. and Emrich, K. and Kraywinkel, K. and Salama, A.
British Journal of Haematology 177 (2): 226-242. April 2017

Enhanced precision and efficiency.
Bashir, S. and Kühn, R.
Nature Biomedical Engineering 1 (11): 856-857. November 2017

Pancreatic cancer models for translational research.
Behrens, D. and Walther, W. and Fichtner, I.
Pharmacology & Therapeutics 173 : 146-158. May 2017

Mathematical modelling of promoter occupancies in MYC-dependent gene regulation.
Benary, U. and Wolf, E. and Wolf, J.
Genomics and Computational Biology 3 (2): e54. 2017

On mass ambiguities in high-resolution shotgun lipidomics.
Bielow, C. and Mastrobuoni, G. and Orioli, M. and Kempa, S.
Analytical Chemistry 89 (5): 2986-2994. 7 March 2017

Identification and functional characterization of hypoxia-induced endoplasmic reticulum stress regulating lncRNA (HypERlnc) in pericytes.
Bischoff, F.C. and Werner, A. and John, D. and Boeckel, J.-N. and Melissari, M.-T. and Grote, P. and Glaser, S.F. and Demolli, S. and Uchida, S. and Michalik, K.M. and Meder, B. and Katus, H.A. and Haas, J. and Chen, W. and Pullamsetti, S.S. and Seeger, W. and Zeiher, A.M. and Dimmeler, S. and Zehendner, C.M.
Circulation Research 121 (4): 368-375. 4 August 2017

A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y. and Malehmir, M. and Healy, M.E. and Bettermann, K. and Lorentzen, A. and Vucur, M. and Ahuja, A.K. and Böhm, F. and Mertens, J.C. and Shimizu, Y. and Frick, L. and Remouchamps, C. and Mutreja, K. and Kähne, T. and Sundaravinayagam, D. and Wolf, M.J. and Rehrauer, H. and Koppe, C. and Speicher, T. and Padrissa-Altés, S. and Maire, R. and Schattenberg, J.M. and Jeong, J.S. and Liu, Lei and Zwirner, S. and Boger, R. and Hüser, N. and Davis, R.J. and Müllhaupt, B. and Moch, H. and Schulze-Bergkamen, H. and Clavien, P.A. and Werner, S. and Borsig, L. and Luther, S.A. and Jost, P.J. and Weinlich, R. and Unger, K. and Behrens, A. and Hillert, L. and Dillon, C. and Di Virgilio, M. and Wallach, D. and Dejardin, E. and Zender, L. and Naumann, M. and Walczak, H. and Green, D.R. and Lopes, M. and Lavrik, I. and Luedde, T. and Heikenwalder, M. and Weber, A.
Cancer Cell 32 (3): 342-359. 11 September 2017

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Bowl, M.R. and Simon, M.M. and Ingham, N.J. and Greenaway, S. and Santos, L. and Cater, H. and Taylor, S. and Mason, J. and Kurbatova, N. and Pearson, S. and Bower, L.R. and Clary, D.A. and Meziane, H. and Reilly, P. and Minowa, O. and Kelsey, L. and Tocchini-Valentini, G.P. and Gao, X. and Bradley, A. and Skarnes, W.C. and Moore, M. and Beaudet, A.L. and Justice, M.J. and Seavitt, J. and Dickinson, M.E. and Wurst, W. and Hrabe de Angelis, M. and Herault, Y. and Wakana, S. and Nutter, L.M.J. and Flenniken, A.M. and McKerlie, C. and Murray, S.A. and Svenson, K.L. and Braun, R.E. and West, D.B. and Lloyd, K.C.K. and Adams, D.J. and White, J. and Karp, N. and Flicek, P. and Smedley, D. and Meehan, T.F. and Parkinson, H.E. and Teboul, L.M. and Wells, S. and Steel, K.P. and Mallon, A.M. and Brown, S.D.M.
Nature Communications 8 (1): 886. 12 October 2017

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Buonocore, F. and Kuehnen, P. and Suntharalingham, J.P. and Del Valle, I. and Digweed, M. and Stachelscheid, H. and Khajavi, N. and Didi, M. and Brady, A.F. and Blankenstein, O. and Procter, A.M. and Dimitri, P. and Wales, J.K.H. and Ghirri, P. and Knoebl, D. and Strahm, B. and Erlacher, M. and Wlodarski, M.W. and Chen, W. and Kokai, G.K. and Anderson, G. and Morrogh, D. and Moulding, D.A. and McKee, S. A. and Niemeyer, C.M. and Grueters, A. and Achermann, J.C.
Journal of Clinical Investigation 127 (5): 1700-1713. 1 May 2017

Assessing the gene regulatory landscape in 1,188 human tumors.
Calabrese, C. and Lehmann, K.V. and Urban, L. and Liu, F. and Erkek, S. and Fonseca, N. and Kahles, A. and Kilpinen-Barrett, L.H. and Markowski, J. and Waszak, S. and Korbel, J. and Zhang, Z. and Brazma, A. and Raetsch, G. and Schwarz, R. and Stegle, O.
bioRxiv : 225441. 29 November 2017

Beyond read-counts: Ribo-seq data analysis to understand the functions of the transcriptome.
Calviello, L. and Ohler, U.
Trends in Genetics 33 (10): 728-744. October 2017

Identification of a novel benzimidazole pyrazolone scaffold that inhibits KDM4 lysine demethylases and reduces proliferation of prostate cancer cells.
Carter, D.M. and Specker, E. and Przygodda, J. and Neuenschwander, M. and von Kries, J.P. and Heinemann, U. and Nazaré, M. and Gohlke, U.
SLAS Discovery 22 (7): 801-812. 1 August 2017

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N. and Naumann, H. and Ruzittu, S. and Mah, N. and Pongrac, I.M. and Cozzitorto, C. and Hommel, A. and Andrade-Navarro, M.A. and Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8 : 14127. 13 February 2017

Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X. and Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214 (11): 3417-3433. 6 November 2017

Endothelial NF-κB blockade abrogates ANCA-induced GN.
Choi, M. and Schreiber, A. and Eulenberg-Gustavus, C. and Scheidereit, C. and Kamps, J. and Kettritz, R.
Journal of the American Society of Nephrology 28 (11): 3191-3204. November 2017

CRISPR/Cas9-mediated in vitro mutagenesis in GC-like B cells.
Chu, V.T. and Graf, R. and Rajewsky, K.
Methods in Molecular Biology 1623 : 135-145. 2017

C/EBP-induced transdifferentiation reveals granulocyte-macrophage precursor-like plasticity of B cells.
Cirovic, B. and Schönheit, J. and Kowenz-Leutz, E. and Ivanovska, J. and Klement, C. and Pronina, N. and Bégay, V. and Leutz, A.
Stem Cell Reports 14 (8): 346-359. 14 February 2017

Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Consentius, P. and Gohlke, U. and Loll, B. and Alings, C. and Heinemann, U. and Wahl, M.C. and Risse, T.
Physical Chemistry Chemical Physics 19 (31): 20723-20734. 9 August 2017

Internal dynamics of the 3-pyrroline-N-oxide ring in spin-labeled proteins.
Consentius, P. and Loll, B. and Gohlke, U. and Alings, C. and Müller, C. and Müller, R. and Teutloff, C. and Heinemann, U. and Kaupp, M. and Wahl, M.C. and Risse, T.
Journal of Physical Chemistry Letters 8 (6): 1113-1117. 16 March 2017

Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.
Cui, H. and Bansal, V. and Grunert, M. and Malecova, B. and Dall Agnese, A. and Latella, L. and Gatto, S. and Ryan, T. and Schulz, K. and Chen, W. and Dorn, C. and Puri, P.L. and Sperling, S.R.
PLoS ONE 12 (6): e0179464. 13 June 2017

Control of gene editing by manipulation of DNA repair mechanisms.
Danner, E. and Bashir, S. and Yumlu, S. and Wurst, W. and Wefers, B. and Kühn, R.
Mammalian Genome 28 (7-8): 262-274. August 2017

Mitochondrial homeostasis: How do dimers of mitofusins mediate mitochondrial fusion?
Daumke, O. and Roux, A.
Current Biology 27 (9): R353-R356. 8 May 2017

The MYCmRNA3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.
Dejure, F.R. and Royla, N. and Herold, S. and Kalb, J. and Walz, S. and Ade, C.P. and Mastrobuoni, G. and Vanselow, J.T. and Schlosser, A. and Wolf, E. and Kempa, S. and Eilers, M.
EMBO Journal 36 (13): 1854-1868. 3 July 2017

Protein Interaction Screen on Peptide Matrix (PRISMA) reveals interaction footprints and the PTM-dependent interactome of intrinsically disordered C/EBPβ.
Dittmar, G. and Perez-Hernandez, D. and Kowenz-Leutz, E. and Kirchner, M. and Kahlert, G. and Wesolowski, R. and Baum, K. and Knoblich, M. and Muller, A. and Wolf, J. and Reimer, U. and Leutz, A.
bioRxiv : 238709. 22 December 2017

Deciphering the ubiquitin code.
Dittmar, G. and Selbach, M.
Molecular Cell 65 (5): 779-780. 2 March 2017

omniCLIP: Bayesian identification of protein-RNA interactions from CLIP-Seq data.
Drewe-Boss, P. and Wessels, H.H. and Ohler, U.
bioRxiv : 161877. 11 July 2017

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J. and Neuenschwander, M. and Yu, Y. and Däbritz, J.H.M. and Neuendorff, N.R. and Schleich, K. and Bittner, A. and Milanovic, M. and Beuster, G. and Radetzki, S. and Specker, E. and Reimann, M. and Rosenbauer, F. and Mathas, S. and Lohneis, P. and Hummel, M. and Dörken, B. and von Kries, J.P. and Lee, S. and Schmitt, C.A.
Blood 129 (1): 71-81. 12 January 2017

Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
Eichenauer, D.A. and Plütschow, A. and Kreissl, S. and Sökler, M. and Hellmuth, J.C. and Meissner, J. and Mathas, S. and Topp, M.S. and Behringer, K. and Klapper, W. and Kuhnert, G. and Dietlein, M. and Kobe, C. and Fuchs, M. and Diehl, V. and Engert, A. and Borchmann, P.
Lancet Oncology 18 (12): 1680-1687. December 2017

In colon epithelia, Clostridium perfringens enterotoxin causes focal leaks by targeting claudins which are apically accessible due to tight junction derangement.
Eichner, M. and Augustin, C. and Fromm, A. and Piontek, A. and Walther, W. and Buecker, R. and Fromm, M. and Krause, G. and Schulzke, J.D. and Guenzel, D. and Piontek, J.
Journal of Infectious Diseases 217 (1): 147-157. 27 December 2017

The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
El-Athman, R. and Genov, N.N. and Mazuch, J. and Zhang, K. and Yu, Y. and Fuhr, L. and Abreu, M. and Li, Y. and Wallach, T. and Kramer, A. and Schmitt, C.A. and Relógio, A.
PLoS Biology 15 (12): e2002940. 7 December 2017

Sugar metabolism of the first thermophilic planctomycete thermogutta terrifontis: comparative genomic and transcriptomic approaches.
Elcheninov, A.G. and Menzel, P. and Gudbergsdottir, S.R. and Slesarev, A.I. and Kadnikov, V.V. and Krogh, A. and Bonch-Osmolovskaya, E.A. and Peng, X. and Kublanov, I.V.
Frontiers in Microbiology 8 : 2140. 2 November 2017

Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination.
Fazal, S.V. and Gomez-Sanchez, J.A. and Wagstaff, L.J. and Musner, N. and Otto, G. and Janz, M. and Mirsky, R. and Jessen, K.R.
Journal of Neuroscience 37 (50): 12297-12313. 13 December 2017

Animal models for personalized treatment options.
Fichtner, I. and Klinghammer, K. and Behrens, D. and Flechsig, S. and Rolff, J. and Becker, M. and Wulf-Goldenberg, A. and Stecklum, M. and Rivera, M. and Brzezicha, B. and Jandrig, B. and Hoffmann, J.
International Journal of Clinical Pharmacology and Therapeutics 55 (8): 698-700. August 2017

Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example.
Fingleton, B. and Lange, K. and Caldwell, B. and Bankaitis, K.V.
Clinical and Experimental Metastasis 34 (8): 443-447. December 2017

Immunomodulatory molecules in renal cell cancer: CD80 and CD86 are expressed on tumor cells.
Flörcken, A. and Johannsen, M. and Nguyen-Hoai, T. and Gerhardt, A. and Miller, K. and Dörken, B. and Pezzutto, A. and Westermann, J. and Jöhrens, K.
International Journal of Clinical and Experimental Pathology 10 (2): 1443-1454. 15 February 2017

Pan-cancer study of heterogeneous RNA aberrations.
Fonseca, N.A. and Kahles, A. and Lehmann, K.V. and Calabrese, C. and Chateigner, A. and Davidson, N.R. and Demircioglu, D. and He, Y. and Lamaze, F.C. and Li, S. and Liu, D. and Liu, F. and Perry, M.D. and Su, H. and Xiang, L. and Zhang, J. and Amin, S.B. and Bailey, P. and Craft, B. and Frenkel-Morgenstern, M. and Goldman, M. and Greger, L. and Hoadley, K.A. and Hou, Y. and Khurana, E. and Korbel, J.O. and Li, C. and Li, X. and Li, X. and Liu, X. and Lu, Y. and Marin, M.G. and Meyerson, M. and Nandi, T. and Nielsen, M.M. and Ojesina, A.I. and Ouellette, B.F.F. and Pan-Hammarstroem, Q. and Pedamallu, C.S. and Pedersen, J.S. and Shiraishi, Y. and Siebert, R. and Soulette, C.M. and Stark, S.G. and Tan, P. and Teh, B.T. and Valencia, A. and Wang, J. and Xing, R. and Xiong, H. and Yakneen, S. and Ye, C. and Yung, C. and Zhang, F. and Zhang, X. and Zheng, L. and Zhu, J. and Zhu, S. and Awadalla, P. and Creighton, C.J. and Goeke, J. and Schwarz, R.F. and Stegle, O. and Wu, K. and Yang, H. and Zhang, Z. and Brazma, A. and Raetsch, G. and Brooks, A.N.
bioRxiv : 183889. 3 September 2017

Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer.
Francy, C.A. and Clinton, R.W. and Froehlich, C. and Murphy, C. and Mears, J.A.
Scientific Reports 7 (1): 10744. 6 September 2017

Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B. and Richter, A. and Richter, A. and Preissner, R. and Schulze-Osthoff, K. and Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292 (16): 6478-6492. 21 April 2017

RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.
Gottlieb, A. and Althoff, K. and Grunewald, L. and Thor, T. and Odersky, A. and Schulte, M. and Deubzer, H.E. and Heukamp, L. and Eggert, A. and Schramm, A. and Schulte, J.H. and Künkele, A.
Oncotarget 8 (17): 27882-27891. 25 April 2017

Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit.
Grosheva, A.S. and Zharkov, D.O. and Stahl, J. and Gopanenko, Al.V. and Tupikin, A.E. and Kabilov, M.R. and Graifer, D.M. and Karpova, G.G.
Nucleic Acids Research 45 (7): 3833-3843. 20 April 2017

McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.
Hafez, D. and Karabacak, A. and Krueger, S. and Hwang, Y.C. and Wang, L.S. and Zinzen, R.P. and Ohler, U.
Genome Biology 18 (1): 199. 26 October 2017

Paracrine and autocrine regulation of gene expression by Wnt-inhibitor Dickkopf in wild-type and mutant hepatocytes.
Hartung, N. and Benary, U. and Wolf, J. and Kofahl, B.
BMC Systems Biology 11 (1): 98. 13 October 2017

Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants.
Hehlmann, R. and Lauseker, M. and Saußele, S. and Pfirrmann, M. and Krause, S. and Kolb, H.J. and Neubauer, A. and Hossfeld, D.K. and Nerl, C. and Gratwohl, A. and Baerlocher, G.M. and Heim, D. and Brümmendorf, T.H. and Fabarius, A. and Haferlach, C. and Schlegelberger, B. and Müller, M.C. and Jeromin, S. and Proetel, U. and Kohlbrenner, K. and Voskanyan, A. and Rinaldetti, S. and Seifarth, W. and Spieß, B. and Balleisen, L. and Goebeler, M.C. and Hänel, M. and Ho, A. and Dengler, J. and Falge, C. and Kanz, L. and Kremers, S. and Burchert, A. and Kneba, M. and Stegelmann, F. and Köhne, C.A. and Lindemann, H.W. and Waller, C.F. and Pfreundschuh, M. and Spiekermann, K. and Berdel, W.E. and Müller, L. and Edinger, M. and Mayer, J. and Beelen, D.W. and Bentz, M. and Link, H. and Hertenstein, B. and Fuchs, R. and Wernli, M. and Schlegel, F. and Schlag, R. and de Wit, M. and Trümper, L. and Hebart, H. and Hahn, M. and Thomalla, J. and Scheid, C. and Schafhausen, P. and Verbeek, W. and Eckart, M.J. and Gassmann, W. and Pezzutto, A. and Schenk, M. and Brossart, P. and Geer, T. and Bildat, S. and Schäfer, E. and Hochhaus, A. and Hasford, J.
Leukemia 31 (11): 2398-2406. November 2017

Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Heidenreich, S. and Witte, N. and Weber, P. and Goehring, I. and Tolkachov, A. and von Loeffelholz, C. and Döcke, S. and Bauer, M. and Stockmann, M. and Pfeiffer, A.F.H. and Birkenfeld, A.L. and Pietzke, M. and Kempa, S. and Muenzner, M. and Schupp, M.
Nature Communications 8 (1): 384. 30 August 2017

ssHMM: extracting intuitive sequence-structure motifs from high-throughput RNA-binding protein data.
Heller, D. and Krestel, R. and Ohler, U. and Vingron, M. and Marsico, A.
Nucleic Acids Research 45 (19): 11004-11018. 2 November 2017

Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation.
Hemmati, P.G. and Vuong, L.G. and Terwey, T.H. and Jehn, C.F. and Le Coutre, P. and Penack, O. and Na, I.K. and Dörken, B. and Arnold, R.
European Journal of Haematology 98 (2): 160-168. February 2017

Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative.
Hendriks, H.R. and Govaerts, A.S. and Fichtner, I. and Burtles, S. and Westwell, A.D. and Peters, G.J.
British Journal of Cancer 117 (2): 195-202. 11 July 2017

CTLA4 promotes Tyk2-STAT3 dependent B-cell oncogenecity.
Herrmann, A. and Lahtz, C. and Nagao, T. and Song, J.Y. and Chan, W.C. and Lee, H. and Yue, C. and Look, T. and Muelfarth, R. and Li, W. and Jenkins, K. and Williams, J. and Budde, L.E. and Forman, S.J. and Kwak, L.W. and Blankenstein, T. and Yu, H.
Cancer Research 77 (18): 5118-5128. 15 September 2017

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
Hessenberger, M. and Zerbes, R.M. and Rampelt, H. and Kunz, S. and Xavier, A.H. and Purfürst, B. and Lilie, H. and Pfanner, N. and van der Laan, M. and Daumke, O.
Nature Communications 8 : 15258. 31 May 2017

Targeting HDAC3 in CREBBP-mutant lymphomas counterstrikes unopposed enhancer deacetylation of B-cell signaling and immune response genes.
Hoepken, U.E.
Cancer Discovery 7 (1): 14-16. January 2017

Determinants of transcription initiation directionality in metazoans.
Ibrahim, M.M. and Karabacak, A. and Glahs, A. and Kolundzic, E. and Hirsekorn, A. and Carda, A. and Tursun, B. and Zinzen, R.P. and Lacadie, S.A. and Ohler, U.
bioRxiv : 224642. 24 November 2017

SIRT1 regulates macrophage self-renewal.
Imperatore, F. and Maurizio, J. and Vargas Aguilar, S. and Busch, C.J. and Favret, J. and Kowenz-Leutz, E. and Cathou, W. and Gentek, R. and Perrin, P. and Leutz, A. and Berruyer, C. and Sieweke, M.H.
EMBO Journal 36 (16): 2353-2372. 15 August 2017

Compound annotation in liquid chromatography/high-resolution mass spectrometry based metabolomics: robust adduct ion determination as a prerequisite to structure prediction in electrospray ionization mass spectra.
Jaeger, C. and Méret, M. and Schmitt, C.A. and Lisec, J.
Rapid Communications in Mass Spectrometry 31 (15): 1261-1266. 15 August 2017

Tracking the evolution of non-small-cell lung cancer.
Jamal-Hanjani, M. and Wilson, G.A. and McGranahan, N. and Birkbak, N.J. and Watkins, T.B.K. and Veeriah, S. and Shafi, S. and Johnson, D.H. and Mitter, R. and Rosenthal, R. and Salm, M. and Horswell, S. and Escudero, M. and Matthews, N. and Rowan, A. and Chambers, T. and Moore, D.A. and Turajlic, S. and Xu, H. and Lee, S.-M. and Forster, M.D. and Ahmad, T. and Hiley, C.T. and Abbosh, C. and Falzon, M. and Borg, E. and Marafioti, T. and Lawrence, D. and Hayward, M. and Kolvekar, S. and Panagiotopoulos, N. and Janes, S.M. and Thakrar, R. and Ahmed, A. and Blackhall, F. and Summers, Y. and Shah, R. and Joseph, L. and Quinn, A.M. and Crosbie, P.A. and Naidu, B. and Middleton, G. and Langman, G. and Trotter, S. and Nicolson, M. and Remmen, H. and Kerr, K. and Chetty, M. and Gomersall, L. and Fennell, D.A. and Nakas, A. and Rathinam, S. and Anand, G. and Khan, S. and Russell, P. and Ezhil, V. and Ismail, B. and Irvin-Sellers, M. and Prakash, V. and Lester, J.F. and Kornaszewska, M. and Attanoos, R. and Adams, H. and Davies, H. and Dentro, S. and Taniere, P. and O'Sullivan, B. and Lowe, H.L. and Hartley, J.A. and Iles, N. and Bell, H. and Ngai, Y. and Shaw, J.A. and Herrero, J. and Szallasi, Z. and Schwarz, R.F. and Stewart, A. and Quezada, S.A. and Le Quesne, J. and Van Loo, P. and Dive, C. and Hackshaw, A. and Swanton, C.
New England Journal of Medicine 376 (22): 2109-2121. 1 June 2017

Tricellulin is a target of the ubiquitin ligase Itch.
Jennek, S. and Mittag, S. and Reiche, J. and Westphal, J.K. and Seelk, S. and Dörfel, M.J. and Pfirrmann, T. and Friedrich, K. and Schütz, A. and Heinemann, U. and Huber, O.
Annals of the New York Academy of Sciences 1397 (1): 157-168. June 2017

Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Jerke, U. and Marino, S.F. and Daumke, O. and Kettritz, R.
Scientific Reports 7 : 43328. 27 February 2017

TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression.
Jiang, C. and Zhu, Y. and Zhou, Z. and Gumin, J. and Bengtsson, L. and Wu, W. and Songyang, Z. and Lang, F.F. and Lin, X.
Oncogene 36 (20): 2813-2823. 18 May 2017

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.
Juneja, M. and Kobelt, D. and Walther, W. and Voss, C. and Smith, J. and Specker, E. and Neuenschwander, M. and Gohlke, B.O. and Dahlmann, M. and Radetzki, S. and Preissner, R. and von Kries, J.P. and Schlag, P.M. and Stein, U.
PLoS Biology 15 (6): e2000784. 1 June 2017

Massively parallel clonal analysis using CRISPR/Cas9 induced genetic scars.
Junker, J.P. and Spanjaard, B. and Peterson-Maduro, J. and Alemany, A. and Hu, B. and Florescu, M. and van Oudenaarden, A.
bioRxiv : 056499. 4 January 2017

Development of mouse model systems of germinal center lymphomas.
Kabrani, E. and Sander, S.
Methods in Molecular Biology 1623 : 233-242. 2017

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T. and Friese, C. and Arina, A. and Idel, C. and Briesemeister, D. and Rothe, M. and Ivanov, A. and Szymborska, A. and Patone, G. and Kunz, S. and Sommermeyer, D. and Engels, B. and Leisegang, M. and Textor, A. and Fehling, H.J. and Fruttiger, M. and Lohoff, M. and Herrmann, A. and Yu, H. and Weichselbaum, R. and Uckert, W. and Hübner, N. and Gerhardt, H. and Beule, D. and Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

mRNA interactome capture in mammalian cells.
Kastelic, N. and Landthaler, M.
Methods 126 : 38-43. 15 August 2017

Choosing wisely - Preclinical test models in the era of precision medicine.
Klinghammer, K. and Walther, W. and Hoffmann, J.
Cancer Treatment Reviews 55 : 36-45. April 2017

FACT sets a barrier for cell fate reprogramming in C. elegans and human.
Kolundzic, E. and Ofenbauer, A. and Uyar, B. and Sommermeier, A. and Seelk, S. and He, M. and Baytek, G. and Akalin, A. and Diecke, S. and Lacadie, S.A. and Tursun, B.
bioRxiv : 185116. 6 September 2017

T cell receptors for clinical therapy: in vitro assessment of toxicity risk.
Kunert, A. and Obenaus, M. and Lamers, C.H.J. and Blankenstein, T. and Debets, R.
Clinical Cancer Research 23 (20): 6012-6020. 15 October 2017

Tomo-seq identifies SOX9 as a key regulator of cardiac fibrosis during ischemic injury.
Lacraz, G.P.A. and Junker, J.P. and Gladka, M.M. and Molenaar, B. and Scholman, K.T. and Vigil-Garcia, M. and Versteeg, D. and de Ruiter, H. and Vermunt, M.W. and Creyghton, M.P. and Huibers, M.M.H. and de Jonge, N. and van Oudenaarden, A. and van Rooij, E.
Circulation 136 (15): 1396-1409. 10 October 2017

Master and commander? FoxO's role in muscle atrophy.
Langer, H.T.
Journal of Physiology 595 (14): 4593-4594. 15 July 2017

Fusion of SpCas9 to E.coli Rec A protein enhances CRISPR-Cas9 mediated gene knockout in mammalian cells.
Lin, L. and Petersen, T.S. and Jensen, K.T. and Bolund, L. and Kühn, R. and Luo, Y.
Journal of Biotechnology 247 : 42-49. 10 April 2017

Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma.
Lodrini, M. and Sprüssel, A. and Astrahantseff, K. and Tiburtius, D. and Konschak, R. and Lode, H.N. and Fischer, M. and Keilholz, U. and Eggert, A. and Deubzer, H.E.
Oncotarget 8 (49): 85234-85251. 17 October 2017

Unbiased identification of T cell receptors targeting immunodominant peptide-MHC complexes for T cell receptor immunotherapy.
Lorenz, F.K.M. and Ellinger, C. and Kieback, E. and Wilde, S. and Lietz, M. and Schendel, D.J. and Uckert, W.
Human Gene Therapy 28 (12): 1158-1168. 1 December 2017

Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.
Lutter, D. and Ullrich, F. and Lueck, J.C. and Kempa, S. and Jentsch, T.J.
Journal of Cell Science 130 (6): 1122-1133. 15 March 2017

Transcriptome-wide identification of RNA-binding protein binding sites using photoactivatable-ribonucleoside-enhanced crosslinking immunoprecipitation (PAR-CLIP).
Maatz, H. and Kolinski, M. and Hubner, N. and Landthaler, M.
Current Protocols in Molecular Biology 118 : 27.6.1-27.6.19. 3 April 2017

Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution.
Mauri, M. and Kirchner, M. and Aharoni, R. and Ciolli Mattioli, C. and van den Bruck, D. and Gutkovitch, N. and Modepalli, V. and Selbach, M. and Moran, Y. and Chekulaeva, M.
Nucleic Acids Research 45 (2): 938-950. 25 January 2017

Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Melo, A.A. and Hegde, B.G. and Shah, C. and Larsson, E. and Isas, J.M. and Kunz, S. and Lundmark, R. and Langen, R. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 114 (22): 5629-5634. 30 May 2017

Degrons in cancer.
Meszaros, B. and Kumar, M. and Gibson, T.J. and Uyar, B. and Dosztanyi, Z.
Science Signaling 10 (470): eaak9982. 14 March 2017

In silico methods for co-transcriptional RNA secondary structure prediction and for investigating alternative RNA structure expression.
Meyer, I.M.
Methods 120 : 3-16. 1 May 2017

Mutations in disordered regions cause disease by creating endocytosis motifs.
Meyer, K. and Uyar, B. and Kirchner, M. and Cheng, J. and Akalin, A. and Selbach, M.
bioRxiv : 141622. 24 May 2017

Ghosts in the shell: identification of microglia in the human central nervous system by P2Y12 receptor.
Mildner, A.
Neural Regeneration Research 12 (4): 570-571. April 2017

Genomic characterization of murine monocytes reveals C/EBPβ transcription factor dependence of Ly6C(-) cells.
Mildner, A. and Schönheit, J. and Giladi, A. and David, E. and Lara-Astiaso, D. and Lorenzo-Vivas, E. and Paul, F. and Chappell-Maor, L. and Priller, J. and Leutz, A. and Amit, I. and Jung, S.
Immunity 46 (5): 849-862. 16 May 2017

DDX54 regulates transcriptome dynamics during DNA damage response.
Milek, M. and Imami, K. and Mukherjee, N. and De Bortoli, F. and Zinnall, U. and Hazapis, O. and Trahan, C. and Oeffinger, M. and Heyd, F. and Ohler, U. and Selbach, M. and Landthaler, M.
Genome Research 27 (8): 1344-1359. August 2017

Tumor-infiltrating merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival.
Miller, N.J. and Church, C.D. and Dong, L. and Crispin, D. and Fitzgibbon, M.P. and Lachance, K. and Jing, L. and Shinohara, M. and Gavvovidis, I. and Willimsky, G. and McIntosh, M. and Blankenstein, T. and Koelle, D.M. and Nghiem, P.
Cancer Immunology Research 5 (2): 137-147. February 2017

Developmental origin and maintenance of distinct testicular macrophage populations.
Mossadegh-Keller, N. and Gentek, R. and Gimenez, G. and Bigot, S. and Mailfert, S. and Sieweke, M.H.
Journal of Experimental Medicine 214 (10): 2829-2841. 2 October 2017

MACC1, a novel player in solid cancer carcinogenesis.
Mudduluru, G. and Ilm, K. and Dahlmann, M. and Stein, U.
In: Mechanisms of Molecular Carcinogenesis - Volume 1. Springer, Cham, 11-38. ISBN 978-3-319-53657-6 2017

Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression.
Mudduluru, G. and Ilm, K. and Fuchs, S. and Stein, U.
Oncotarget 8 (13): 21081-21094. 28 March 2017

Integrative classification of human coding and noncoding genes through RNA metabolism profiles.
Mukherjee, N. and Calviello, L. and Hirsekorn, A. and de Pretis, S. and Pelizzola, M. and Ohler, U.
Nature Structural & Molecular Biology 24 (1): 86-96. January 2017

Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Mönke, G. and Cristiano, E. and Finzel, A. and Friedrich, D. and Herzel, H. and Falcke, M. and Loewer, A.
Scientific Reports 7 : 46571. 18 April 2017

Identification of the elementary structural units of the DNA damage response.
Natale, F. and Rapp, A. and Yu, W. and Maiser, A. and Harz, H. and Scholl, A. and Grulich, S. and Anton, T. and Hoerl, D. and Chen, W. and Durante, M. and Taucher-Scholz, G. and Leonhardt, H. and Cardoso, M.C.
Nature Communications 8 : 15760. 12 June 2017

Underlying mechanisms for distant metastasis - molecular biology.
Pachmayr, E. and Treese, C. and Stein, U.
Visceral Medicine 33 (1): 11-20. February 2017

Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy.
Pahle, J. and Menzel, L. and Niesler, N. and Kobelt, D. and Aumann, J. and Rivera, M. and Walther, W.
BMC Cancer 17 (1): 129. 13 February 2017

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.
Pajtler, K.W. and Sadowski, N. and Ackermann, S. and Althoff, K. and Schönbeck, K. and Batzke, K. and Schäfers, S. and Odersky, A. and Heukamp, L. and Astrahantseff, K. and Künkele, A. and Deubzer, H.E. and Schramm, A. and Sprüssel, A. and Thor, T. and Lindner, S. and Eggert, A. and Fischer, M. and Schulte, J.H.
Oncotarget 8 (4): 6730-6741. 24 January 2017

Translation of circRNAs.
Pamudurti, NR. and Bartok, O. and Jens, M. and Ashwal-Fluss, R. and Stottmeister, C. and Ruhe, L. and Hanan, M. and Wyler, E. and Perez-Hernandez, D. and Ramberger, E. and Shenzis, S. and Samson, M. and Dittmar, G. and Landthaler, M. and Chekulaeva, M. and Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.
Park, T.J. and Reznick, J. and Peterson, B.L. and Blass, G. and Omerbašić, D. and Bennett, N.C. and Kuich, P.H.J.L. and Zasada, C. and Browe, B.M. and Hamann, W. and Applegate, D.T. and Radke, M.H. and Kosten, T. and Lutermann, H. and Gavaghan, V. and Eigenbrod, O. and Bégay, V. and Amoroso, V. G. and Govind, V. and Minshall, R.D. and Smith, E.S.J. and Larson, J. and Gotthardt, M. and Kempa, S. and Lewin, G.R.
Science 356 (6335): 307-311. 21 April 2017

Quantitative GTPase affinity purification identifies Rho family protein interaction partners.
Paul, F. and Zauber, H. and von Berg, L. and Rocks, O. and Daumke, O. and Selbach, M.
Molecular & Cellular Proteomics 16 (1): 73-85. 1 January 2017

Pontine tegmental cap dysplasia in an extremely preterm infant and review of the literature.
Picker-Minh, S. and Hartenstein, S. and Proquitte, H. and Froehler, S. and Raile, V. and Kraemer, N. and Apeshiotis, S. and Leipoldt, M. and Kalache, K.D. and Morris-Rosendahl, D. and Boltshauser, E. and Chen, W. and Kaindl, A.M.
Journal of Child Neurology 32 (3): 334-340. March 2017

JACUSA: site-specific identification of RNA editing events from replicate sequencing data.
Piechotta, M. and Wyler, E. and Ohler, U. and Landthaler, M. and Dieterich, C.
BMC Bioinformatics 18 (1): 7. 3 January 2017

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Pieper, K. and Tan, J. and Piccoli, L. and Foglierini, M. and Barbieri, S. and Chen, Y. and Silacci-Fregni, C. and Wolf, T. and Jarrossay, D. and Anderle, M. and Abdi, A. and Ndungu, F.M. and Doumbo, O.K. and Traore, B. and Tran, T.M. and Jongo, S. and Zenklusen, I. and Crompton, P.D. and Daubenberger, C. and Bull, P.C. and Sallusto, F. and Lanzavecchia, A.
Nature 548 (7669): 597-601. 31 August 2017

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M. and Glažar, P. and Hernandez-Miranda, L.R. and Memczak, S. and Wolf, S.A. and Rybak-Wolf, A. and Filipchyk, A. and Klironomos, F. and Cerda Jara, C.A. and Fenske, P. and Trimbuch, T. and Zywitza, V. and Plass, M. and Schreyer, L. and Ayoub, S. and Kocks, C. and Kühn, R. and Rosenmund, C. and Birchmeier, C. and Rajewsky, N.
Science 357 (6357): eaam8526. 22 September 2017

Evolutionary plasticity in the innate immune function of Akirin.
Polanowska, J. and Chen, J.X. and Soule, J. and Omi, S. and Belougne, J. and Taffoni, C. and Pujol, N. and Selbach, M. and Zugasti, O. and Ewbank, J.J.
bioRxiv : 230102. 6 December 2017

Different inhibitory potencies of oseltamivir carboxylate, zanamivir, and several tannins on bacterial and viral neuraminidases as assessed in a cell-free fluorescence-based enzyme inhibition assay.
Quosdorf, S. and Schuetz, A. and Kolodziej, H.
Molecules 22 (11): 1989. 17 November 2017

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.
Radhakrishnan, H. and Ilm, K. and Walther, W. and Shirasawa, S. and Sasazuki, T. and Daniel, P.T. and Gillissen, B. and Stein, U.
Cancer Letters 403 : 231-245. 10 September 2017

MAD2L2 promotes open chromatin in embryonic stem cells and derepresses the Dppa3 locus.
Rahjouei, A. and Pirouz, M. and Di Virgilio, M. and Kamin, D. and Kessel, M.
Stem Cell Reports 8 (4): 813-821. 11 April 2017

George Klein: 1925-2016.
Rajewsky, K.
National Academy of Sciences (U.S.A.). 28 March 2017

Increased salt consumption induces body water conservation and decreases fluid intake.
Rakova, N. and Kitada, K. and Lerchl, K. and Dahlmann, A. and Birukov, A. and Daub, S. and Kopp, C. and Pedchenko, T. and Zhang, Y. and Beck, L. and Johannes, B. and Marton, A. and Müller, D.N. and Rauh, M. and Luft, F.C. and Titze, J.
Journal of Clinical Investigation 127 (5): 1932-1943. 1 May 2017

Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells.
Riemann, M. and Andreas, N. and Fedoseeva, M. and Meier, E. and Weih, D. and Freytag, H. and Schmidt-Ullrich, R. and Klein, U. and Wang, Z.Q. and Weih, F.
Journal of Autoimmunity 81 : 56-67. July 2017

Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K. and Shi, Y. and Jacobi, A. and Kräter, M. and Kalupa, M. and McGearey, A. and Mertlitz, S. and Cordes, S. and Schrezenmeier, J.F. and Mengwasser, J. and Westphal, S. and Perez-Hernandez, D. and Schmitt, C. and Dittmar, G. and Guck, J. and Penack, O.
Blood 129 (14): 2021-2032. 6 April 2017

Childhood cancer predisposition syndromes - a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.
Ripperger, T. and Bielack, S.S. and Borkhardt, A. and Brecht, I.B. and Burkhardt, B. and Calaminus, G. and Debatin, K.M. and Deubzer, H. and Dirksen, U. and Eckert, C. and Eggert, A. and Erlacher, M. and Fleischhack, G. and Frühwald, M.C. and Gnekow, A. and Goehring, G. and Graf, N. and Hanenberg, H. and Hauer, J. and Hero, B. and Hettmer, S. and von Hoff, K. and Horstmann, M. and Hoyer, J. and Illig, T. and Kaatsch, P. and Kappler, R. and Kerl, K. and Klingebiel, T. and Kontny, U. and Kordes, U. and Körholz, D. and Koscielniak, E. and Kramm, C.M. and Kuhlen, M. and Kulozik, A.E. and Lamottke, B. and Leuschner, I. and Lohmann, D.R. and Meinhardt, A. and Metzler, M. and Meyer, L.H. and Moser, O. and Nathrath, M. and Niemeyer, C.M. and Nustede, R. and Pajtler, K.W. and Paret, C. and Rasche, M. and Reinhardt, D. and Rieß, O. and Russo, A. and Rutkowski, S. and Schlegelberger, B. and Schneider, D. and Schneppenheim, R. and Schrappe, M. and Schroeder, C. and von Schweinitz, D. and Simon, T. and Sparber-Sauer, M. and Spix, C. and Stanulla, M. and Steinemann, D. and Strahm, B. and Temming, P. and Thomay, K. and von Bueren, A.O. and Vorwerk, P. and Witt, O. and Wlodarski, M. and Wössmann, W. and Zenker, M. and Zimmermann, S. and Pfister, S.M. and Kratz, C.P.
American Journal of Medical Genetics Part A 173 (4): 1017-1037. April 2017

Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies.
Rohr, U.P. and Herrmann, P. and Ilm, K. and Zhang, H. and Lohmann, S. and Reiser, A. and Muranyi, A. and Smith, J. and Burock, S. and Osterland, M. and Leith, K. and Singh, S. and Brunhoeber, P. and Bowermaster, R. and Tie, J. and Christie, M. and Wong, H.L. and Waring, P. and Shanmugam, K. and Gibbs, P. and Stein, U.
Annals of Oncology 28 (8): 1869-1875. 1 August 2017

The answer's in the tail: MYC mRNA has a metabolic sensor that supports cancer chemoresistance.
Royla, N. and Kempa, S.
Molecular & Cellular Oncology 4 (4): e1338209. 5 July 2017

Chimeric PD-1:28 receptor upgrades low-avidity T cells and restores effector function of tumor-infiltrating lymphocytes for adoptive cell therapy.
Schlenker, R. and Olguín-Contreras, L.F. and Leisegang, M. and Schnappinger, J. and Disovic, A. and Rühland, S. and Nelson, P.J. and Leonhardt, H. and Harz, H. and Wilde, S. and Schendel, D.J. and Uckert, W. and Willimsky, G. and Noessner, E.
Cancer Research 77 (13): 3577-3590. 1 July 2017

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt, F. and Gasparoni, N. and Gasparoni, G. and Gianmoena, K. and Cadenas, C. and Polansky, J.K. and Ebert, P. and Nordstroem, K. and Barann, M. and Sinha, A. and Froehler, S. and Xiong, J. and Dehghani Amirabad, A. and Behjati Ardakani, F. and Hutter, B. and Zipprich, G. and Felder, B. and Eils, J. and Brors, B. and Chen, W. and Hengstler, J.G. and Hamann, A. and Lengauer, T. and Rosenstiel, P. and Walter, J. and Schulz, M.H.
Nucleic Acids Research 45 (1): 54-66. 9 January 2017

Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Schuetz, A. and Radusheva, V. and Krug, S.M. and Heinemann, U.
Annals of the New York Academy of Sciences 1405 (1): 147-159. October 2017

Structural basis for aryl hydrocarbon receptor-mediated gene activation.
Schulte, K.W. and Green, E. and Wilz, A. and Platten, M. and Daumke, O.
Structure 25 (7): 1025-1033. 5 July 2017

Activation-dependent TRAF3 exon 8 alternative splicing is controlled by CELF2 and hnRNP C binding to an upstream intronic element.
Schultz, A.S. and Preussner, M. and Bunse, M. and Karni, R. and Heyd, F.
Molecular and Cellular Biology 37 (7): e.00488-16. April 2017

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Schütte, M. and Risch, T. and Abdavi-Azar, N. and Boehnke, K. and Schumacher, D. and Keil, M. and Yildiriman, R. and Jandrasits, C. and Borodina, T. and Amstislavskiy, V. and Worth, C.L. and Schweiger, C. and Liebs, S. and Lange, M. and Warnatz, H.J. and Butcher, L.M. and Barrett, J.E. and Sultan, M. and Wierling, C. and Golob-Schwarzl, N. and Lax, S. and Uranitsch, S. and Becker, M. and Welte, Y. and Regan, J.L. and Silvestrov, M. and Kehler, I. and Fusi, A. and Kessler, T. and Herwig, R. and Landegren, U. and Wienke, D. and Nilsson, M. and Velasco, J.A. and Garin-Chesa, P. and Reinhard, C. and Beck, S. and Schäfer, R. and Regenbrecht, C.R.A. and Henderson, D. and Lange, B. and Haybaeck, J. and Keilholz, U. and Hoffmann, J. and Lehrach, H. and Yaspo, M.L.
Nature Communications 8 : 14262. 10 February 2017

2017 GPOH guidelines for diagnosis and treatment of patients with neuroblastic tumors.
Simon, T. and Hero, B. and Schulte, J.H. and Deubzer, H. and Hundsdoerfer, P. and von Schweinitz, D. and Fuchs, J. and Schmidt, M. and Prasad, V. and Krug, B. and Timmermann, B. and Leuschner, I. and Fischer, M. and Langer, T. and Astrahantseff, K. and Berthold, F. and Lode, H. and Eggert, A.
Klinische Padiatrie 229 (3): 147-167. May 2017

Massively parallel single cell lineage tracing using CRISPR/Cas9 induced genetic scars.
Spanjaard, B. and Hu, B. and Mitic, N. and Junker, J.P.
bioRxiv : 205971. 19 October 2017

Methods for lineage tracing on the organism-wide level.
Spanjaard, B. and Junker, J.P.
Current Opinion in Cell Biology 49 : 16-21. December 2017

The splenic marginal zone shapes the phenotype of leukemia B cells and facilitates their niche-specific retention and survival.
Stache, V. and Verlaat, L. and Gätjen, M. and Heinig, K. and Westermann, J. and Rehm, A. and Höpken, U.E.
OncoImmunology 6 (6): e1323155. 6 June 2017

NF-κB activation protects oligodendrocytes against inflammation.
Stone, S. and Jamison, S. and Yue, Y. and Durose, W. and Schmidt-Ullrich, R. and Lin, W.
Journal of Neuroscience 37 (38): 9332-9344. 20 September 2017

UroFors: Konstituierung eines Interessensverbundes fuer Naturwissenschaftler in der urologischen Forschung [UroFors: establishment of an interest group for natural scientists in urological research].
Stope, M.B. and Dansranjavin, T. and Erb, H. and Erdmann, K. and Fendler, A. and Hoelters, S. and Juengel, E. and Nitschke, K. and Salomo, K. and Seidel, P. and Skowron, M.A. and Wach, S. and Becker, C.
Urologe 56 (4): 515-518. April 2017

Molecular simulations suggest a force-dependent mechanism of vinculin activation.
Sun, L. and Noel, J.K. and Levine, H. and Onuchic, J.N.
Biophysical Journal 113 (8): 1697-1710. 17 October 2017

An immediate-late gene expression module decodes ERK signal duration.
Uhlitz, F. and Sieber, A. and Wyler, E. and Fritsche-Guenther, R. and Meisig, J. and Landthaler, M. and Klinger, B. and Blüthgen, N.
Molecular Systems Biology 13 (5): 928. 3 May 2017

RCAS: an RNA centric annotation system for transcriptome-wide regions of interest.
Uyar, B. and Yusuf, D. and Wurmus, R. and Rajewsky, N. and Ohler, U. and Akalin, A.
Nucleic Acids Research 45 (10): e91. 2 June 2017

Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors.
Valenti, G. and Quinn, H.M. and Heynen, G.J.J.E. and Lan, L. and Holland, J.D. and Vogel, R. and Wulf-Goldenberg, A. and Birchmeier, W.
Cancer Research 77 (8): 2134-2147. 15 April 2017

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.
Varano, G. and Raffel, S. and Sormani, M. and Zanardi, F. and Lonardi, S. and Zasada, C. and Perucho, L. and Petrocelli, V. and Haake, A. and Lee, A.K. and Bugatti, M. and Paul, U. and Van Anken, E. and Pasqualucci, L. and Rabadan, R. and Siebert, R. and Kempa, S. and Ponzoni, M. and Facchetti, F. and Rajewsky, K. and Casola, S.
Nature 546 (7657): 302-306. 8 June 2017

A multi-step transcriptional and chromatin state cascade underlies motor neuron programming from embryonic stem cells.
Velasco, S. and Ibrahim, M.M. and Kakumanu, A. and Garipler, G. and Aydin, B. and Al-Sayegh, M.A. and Hirsekorn, A. and Abdul-Rahman, F. and Satija, R. and Ohler, U. and Mahony, S. and Mazzoni, E.O.
Cell Stem Cell 20 (2): 205-217. 2 February 2017

Fibril branching dominates self-assembly of mutant huntingtin exon-1 aggregates in vitro.
Wagner, A.S. and Politi, A.Z. and Steinhof, A. and Bravo-Rodriguez, K. and Buntru, A. and Strempel, N.U. and Brusendorf, L. and Haenig, C. and Boeddrich, A. and Plassmann, S. and Ramirez-Anguita, J.M. and Baum, K. and Sanchez-Garcia, E. and Wolf, J. and Wanker, E.E.
bioRxiv : 195297. 19 October 2017

In vitro and in vivo investigations into the carbene gold chloride and thioglucoside anticancer drug candidates NHC-AuCl and NHC-AuSR.
Walther, Wolfgang and Dada, Oyinlola and O’Beirne, Cillian and Ott, Ingo and Sanchez-Sanz, Goar and Schmidt, Claudia and Werner, Carsta and Zhu, Xiangming and Tacke, Matthias
Letters in Drug Design & Discovery 14 (2): 125-134. 2017

Decitabine inhibits T cell proliferation via a novel TET2-dependent mechanism and exerts potent protective effect in mouse auto- and allo-immunity models.
Wang, X. and Wang, J. and Yu, Y. and Ma, T. and Chen, P. and Zhou, B. and Tao, R.
Oncotarget 8 (34): 56802-56815. 22 August 2017

EBI2 is highly expressed in multiple sclerosis lesions and promotes early CNS migration of encephalitogenic CD4 T cells.
Wanke, F. and Moos, S. and Croxford, A.L. and Heinen, A.P. and Gräf, S. and Kalt, B. and Tischner, D. and Zhang, J. and Christen, I. and Bruttger, J. and Yogev, N. and Tang, Y. and Zayoud, M. and Israel, N. and Karram, K. and Reißig, S. and Lacher, S.M. and Reichhold, C. and Mufazalov, I.A. and Ben-Nun, A. and Kuhlmann, T. and Wettschureck, N. and Sailer, A.W. and Rajewsky, K. and Casola, S. and Waisman, A. and Kurschus, F.C.
Cell Reports 18 (5): 1270-1284. 31 January 2017

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes.
Waszak, S.M. and Tiao, G. and Zhu, B. and Rausch, T. and Muyas, F. and Rodriguez-Martin, B. and Rabionet, R. and Yakneen, S. and Escaramis, G. and Li, Y. and Saini, N. and Roberts, S.A. and Demidov, G.M. and Pitkanen, E. and Delaneau, O. and Heredia-Genestar, J.M. and Weischenfeldt, J. and Shringarpure, S.S. and Chen, J. and Nakagawa, H. and Alexandrov, L.B. and Drechsel, O. and Dursi, L.J. and Segre, A.V. and Garrison, E. and Erkek, S. and Habermann, N. and Urban, L. and Khurana, E. and Cafferkey, A. and Hayashi, S. and Imoto, S. and Aaltonen, L.A. and Alvarez, E.G. and Baez-Ortega, A. and Bailey, M. and Bosio, M. and Bruzos, A.L. and Buchhalter, I. and Bustamante, C.D. and Calabrese, C. and DiBiase, A. and Gerstein, M. and Holik, A.Z. and Hua, X. and Huang, K.l. and Letunic, I. and Klimczak, L.J. and Koster, R. and Kumar, S. and McLellan, M. and Mashl, J. and Mirabello, L. and Newhouse, S. and Prasad, A. and Raetsch, G. and Schlesner, M. and Schwarz, R. and Sharma, P. and Shmaya, T. and Sidiropoulos, N. and Song, L. and Susak, H. and Tanskanen, T. and Tojo, M. and Wedge, D.C. and Wright, M. and Wu, Y. and Ye, K. and Yellapantula, V. D. and Zamora, J. and Butte, A.J. and Getz, G. and Simpson, J. and Ding, L. and Marques-Bonet, T. and Navarro, A. and Brazma, A. and Campbell, P. and Chanock, S.J. and Chatterjee, N. and Stegle, O. and Siebert, R. and Ossowski, S. and Harismendy, O. and Gordenin, D.A. and Tubio, J.M.C. and De La Vega, F.M. and Easton, D.F. and Estivill, X. and Korbel, J.
bioRxiv : 208330. 1 November 2017

Gene editing in mouse zygotes using the CRISPR/Cas9 system.
Wefers, B. and Bashir, S. and Rossius, J. and Kühn, R.
Methods 121-122 : 55-67. 15 May 2017

Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.
Wetzel, C. and Pifferi, S. and Picci, C. and Gök, C. and Hoffmann, D. and Bali, K.K. and Lampe, A. and Lapatsina, L. and Fleischer, R. and Smith, E.S.J. and Bégay, V. and Moroni, M. and Estebanez, L. and Kühnemund, J. and Walcher, J. and Specker, E. and Neuenschwander, M. and von Kries, J.P. and Haucke, V. and Kuner, R. and Poulet, J.F.A. and Schmoranzer, J. and Poole, K. and Lewin, G.R.
Nature Neuroscience 20 (2): 209-218. February 2017

Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog).
Will, A.J. and Cova, G. and Osterwalder, M. and Chan, W.L. and Wittler, L. and Brieske, N. and Heinrich, V. and de Villartay, J.P. and Vingron, M. and Klopocki, E. and Visel, A. and Lupiáñez, D.G. and Mundlos, S.
Nature Genetics 49 (10): 1539-1545. October 2017

Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use.
Wisskirchen, K. and Metzger, K. and Schreiber, S. and Asen, T. and Weigand, L. and Dargel, C. and Witter, K. and Kieback, E. and Sprinzl, M.F. and Uckert, W. and Schiemann, M. and Busch, D.H. and Krackhardt, A.M. and Protzer, U.
PLoS ONE 12 (8): e0182936. 8 August 2017

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
Wong, J.B. and Hewitt, S.L. and Heltemes-Harris, L.M. and Mandal, M. and Johnson, K. and Rajewsky, K. and Koralov, S.B. and Clark, M.R. and Farrar, M.A. and Skok, J.A.
bioRxiv : 214908. 13 November 2017

Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.
Wurster, K.D. and Hummel, F. and Richter, J. and Giefing, M. and Hartmann, S. and Hansmann, M.L. and Kreher, S. and Köchert, K. and Krappmann, D. and Klapper, W. and Hummel, M. and Wenzel, S.S. and Lenz, G. and Janz, M. and Dörken, B. and Siebert, R. and Mathas, S.
Leukemia 31 (3): 602-613. March 2017

Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.
Wyler, E. and Menegatti, J. and Franke, V. and Kocks, C. and Boltengagen, A. and Hennig, T. and Theil, K. and Rutkowski, A. and Ferrai, C. and Baer, L. and Kermas, L. and Friedel, C. and Rajewsky, N. and Akalin, A. and Dölken, L. and Grässer, F. and Landthaler, M.
Genome Biology 18 (1): 209. 31 October 2017

Rattus norvegicus BN/SHR liver and heart left ventricle ribosomal RNA depleted directional RNA sequencing.
Wyler, E. and van Heesch, S. and Adami, E. and Hubner, N. and Landthaler, M.
BMC Research Notes 10 (1): 395. 11 August 2017

Anisotropic fluctuations in the ribosome determine tRNA kinetics.
Yang, H. and Noel, J.K. and Whitford, P.C.
Journal of Physical Chemistry B 121 (47): 10593-10601. 30 November 2017

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.
Young, E. and Noerenberg, D. and Mansouri, L. and Ljungström, V. and Frick, M. and Sutton, L.A. and Blakemore, S.J. and Galan-Sousa, J. and Plevova, K. and Baliakas, P. and Rossi, D. and Clifford, R. and Roos-Weil, D. and Navrkalova, V. and Dörken, B. and Schmitt, C.A. and Smedby, K.E. and Juliusson, G. and Giacopelli, B. and Blachly, J.S. and Belessi, C. and Panagiotidis, P. and Chiorazzi, N. and Davi, F. and Langerak, A.W. and Oscier, D. and Schuh, A. and Gaidano, G. and Ghia, P. and Xu, W. and Fan, L. and Bernard, O.A. and Nguyen-Khac, F. and Rassenti, L. and Li, J. and Kipps, T.J. and Stamatopoulos, K. and Pospisilova, S. and Zenz, T. and Oakes, C.C. and Strefford, J.C. and Rosenquist, R. and Damm, F.
Leukemia 31 (7): 1547-1554. July 2017

Gene editing and clonal isolation of human induced pluripotent stem cells using CRISPR/Cas9.
Yumlu, S. and Stumm, J. and Bashir, S. and Dreyer, A.K. and Lisowski, P. and Danner, E. and Kühn, R.
Methods 121-122 : 29-44. 15 May 2017

Approaches and techniques to characterize cancer metabolism in vitro and in vivo.
Zaimenko, I. and Lisec, J. and Stein, U. and Brenner, W.
Biochimica et Biophysica Acta - Reviews on Cancer 1868 (2): 412-419. December 2017

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A. and van den Bruck, D. and Ciolli Mattioli, C. and Franke, V. and Imami, K. and McShane, E. and Moreno-Estelles, M. and Calviello, L. and Filipchyk, A. and Peguero-Sanchez, E. and Müller, T. and Woehler, A. and Birchmeier, C. and Merino, E. and Rajewsky, N. and Ohler, U. and Mazzoni, E.O. and Selbach, M. and Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Picky: a simple method designer for targeted proteomics.
Zauber, H. and Kirchner, M. and Selbach, M.
bioRxiv : 163154. 6 October 2017

RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints.
Zhong, Y. and Karaletsos, T. and Drewe, P. and Sreedharan, V.T. and Kuo, D. and Singh, K. and Wendel, H.G. and Raetsch, G.
Bioinformatics 33 (1): 139-141. 1 January 2017

Trained macrophages support hygiene hypothesis.
de Laval, B. and Sieweke, M.H.
Nature Immunology 18 (12): 1279-1280. 16 November 2017

Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations.
van den Brink, S.C. and Sage, F. and Vertesy, A. and Spanjaard, B. and Peterson-Maduro, J. and Baron, C.S. and Robin, C. and van Oudenaarden, A.
Nature Methods 14 (10): 935-936. 29 September 2017

2016

Metabolism in cancer.
Cramer, T. and Schmitt, C., eds.
Recent Results in Cancer Research, 207 . Springer (Switzerland). ISBN 978-3-319-42118-6 2016

KCNE2 and gastric cancer: bench to bedside.
Abbott, G.W. and Roepke, T.K.
Oncotarget 7 (14): 17286-17287. 5 April 2016

The metabolic background is a global player in Saccharomyces gene expression epistasis.
Alam, M.T. and Zelezniak, A. and Mülleder, M. and Shliaha, P. and Schwarz, R. and Capuano, F. and Vowinckel, J. and Radmaneshfar, E. and Krüger, A. and Calvani, E. and Michel, S. and Börno, S. and Christen, S. and Patil, K.R. and Timmermann, B. and Lilley, K.S. and Ralser, M.
Nature Microbiology 1 : 15030. 1 February 2016

Membrane fission by dynamin: what we know and what we need to know.
Antonny, B. and Burd, C. and De Camilli, P. and Chen, E. and Daumke, O. and Faelber, K. and Ford, M. and Frolov, V.A. and Frost, A. and Hinshaw, J.E. and Kirchhausen, T. and Kozlov, M.M. and Lenz, M. and Low, H.H. and McMahon, H. and Merrifield, C. and Pollard, T.D. and Robinson, P.J. and Roux, A. and Schmid, S.
EMBO Journal 35 (21): 2270-2284. 2 November 2016

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A. and Roske, Y. and Barth, C. and Lleras Forero, L. and Bravo-Rodriguez, K. and Redel, Al. and Kostova, S. and McShane, E. and Opitz, R. and Faelber, K. and Rau, K. and Mielke, T. and Daumke, O. and Selbach, M. and Sanchez-Garcia, E. and Rocks, O. and Panáková, D. and Heinemann, U. and Wanker, E.E.
Nature Communications 7 : 13047. 20 October 2016

Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk.
Ashktorab, H. and Hermann, P. and Nouraie, M. and Shokrani, B. and Lee, E. and Haidary, T. and Brim, H. and Stein, U.
Journal of Translational Medicine 14 (1): 215. 20 July 2016

Dynamics of the ligand binding domain layer during AMPA receptor activation.
Baranovic, J. and Chebli, M. and Salazar, H. and Carbone, A.L. and Faelber, K. and Lau, A.Y. and Daumke, O. and Plested, A.J.R.
Biophysical Journal 110 (4): 896-911. 23 February 2016

OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation.
Barrera, M. and Koob, S. and Dikov, D. and Vogel, F. and Reichert, A.S.
FEBS Letters 590 (19): 3309-3322. October 2016

Feedback, mass conservation and reaction kinetics impact the robustness of cellular oscillations.
Baum, K. and Politi, A.Z. and Kofahl, B. and Steuer, R. and Wolf, J.
PLoS Computational Biology 12 (12): e1005298. 27 December 2016

Poly(ADP-ribosyl)ation of Methyl CpG binding domain protein 2 regulates chromatin structure.
Becker, A. and Zhang, P. and Allmann, L. and Meilinger, D. and Bertulat, B. and Eck, D. and Hofstaetter, M. and Bartolomei, G. and Hottiger, M.O. and Schreiber, V. and Leonhardt, H. and Cardoso, M.C.
Journal of Biological Chemistry 291 (10): 4873-4881. 4 March 2016

The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration.
Becker, M.S. and Müller, P.M. and Bajorat, J. and Schroeder, A. and Giaisi, M. and Amin, E. and Ahmadian, M.R. and Rocks, O. and Köhler, R. and Krammer, P.H. and Li-Weber, M.
Oncotarget 7 (32): 51908-51921. 9 August 2016

A c-Myc/miR17-92/Pten axis controls PI3K-mediated positive and negative selection in B cell development and reconstitutes CD19 deficiency.
Benhamou, D. and Labi, V. and Novak, R. and Dai, I. and Shafir-Alon, S. and Weiss, A. and Gaujoux, R. and Arnold, R. and Shen-Orr, S.S. and Rajewsky, K. and Melamed, D.
Cell Reports 16 (2): 419-431. 12 July 2016

Isolation of eosinophils from the lamina propria of the murine small intestine.
Berek, C. and Beller, A. and Chu, V.T.
Methods in Molecular Biology 1422 : 213-221. 2016

Multiple myeloma cells modify VEGF/IL-6 levels and osteogenic potential of bone marrow stromal cells via Notch/miR-223.
Berenstein, R. and Nogai, A. and Waechter, M. and Blau, O. and Kuehnel, A. and Schmidt-Hieber, M. and Kunitz, A. and Pezzutto, A. and Dörken, B. and Blau, I.W.
Molecular Carcinogenesis 55 (12): 1927-1939. December 2016

Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune, M.T. and Gee, M.H. and Bunse, M. and Lee, M.S. and Gschweng, E.H. and Pagadala, M.S. and Zhou, J. and Cheng, D. and Heath, J.R. and Kohn, D.B. and Kuhns, M.S. and Uckert, W. and Baltimore, D.
eLife 5 : e19095. 8 November 2016

Orchestrating Wnt signalling for metabolic liver zonation.
Birchmeier, W.
Nature Cell Biology 18 (5): 463-465. May 2016

Receptor combinations hone T-cell therapy.
Blankenstein, T.
Nature Biotechnology 34 (4): 389-391. 7 April 2016

Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.
Braten, O. and Livneh, I. and Ziv, T. and Admon, A. and Kehat, I. and Caspi, L.H. and Gonen, H. and Bercovich, B. and Godzik, A. and Jahandideh, S. and Jaroszewski, L. and Sommer, T. and Kwon, Y.T. and Guharoy, M. and Tompa, P. and Ciechanover, A.
Proceedings of the National Academy of Sciences of the United States of America 113 (32): E4639-E4647. 9 August 2016

Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes.
Burridge, P.W. and Diecke, S. and Matsa, E. and Sharma, A. and Wu, H. and Wu, J.C.
Methods in Molecular Biology 1353 : 119-130. 2016

Detecting actively translated open reading frames in ribosome profiling data.
Calviello, L. and Mukherjee, N. and Wyler, E. and Zauber, H. and Hirsekorn, A. and Selbach, M. and Landthaler, M. and Obermayer, B. and Ohler, U.
Nature Methods 13 (2): 165-170. February 2016

On fine stochastic simulations of liposome-encapsulated PUREsystem(TM).
Calviello, L. and Lazzerini-Ospri, L. and Marangoni, R.
In: 10th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2015, 22-25 Sept 2015, Bari, Italy. 2016

A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression.
Casado-Medrano, V. and Barrio-Real, L. and García-Rostán, G. and Baumann, M. and Rocks, O. and Caloca, M.J.
Oncotarget 7 (19): 28301-28319. 10 May 2016

Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63 (6): 918-925. 15 September 2016

miR-23~27~24 clusters control effector T cell differentiation and function.
Cho, S. and Wu, C.J. and Yasuda, T. and Cruz, L.O. and Khan, A.A. and Lin, L.L. and Nguyen, D.T. and Miller, M. and Lee, H.M. and Kuo, M.L. and Broide, D.H. and Rajewsky, K. and Rudensky, A.Y. and Lu, L.F.
Journal of Experimental Medicine 213 (2): 235-249. 8 February 2016

T cell PTLD successfully treated with single-agent brentuximab vedotin first-line therapy.
Choi, M. and Fink, S. and Prasad, V. and Anagnostopoulos, I. and Reinke, P. and Schmitt, C.A.
Transplantation 100 (3): e8-e10. March 2016

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T. and Graf, R. and Wirtz, T. and Weber, T. and Favret, J. and Li, X. and Petsch, K. and Tran, N.T. and Sieweke, M.H. and Berek, C. and Kühn, R. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (44): 12514-12519. 1 November 2016

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.
Chu, V.T. and Weber, T. and Graf, R. and Sommermann, T. and Petsch, K. and Sack, U. and Volchkov, P. and Rajewsky, K. and Kühn, R.
BMC Biotechnology 16 (1): 4. 16 January 2016

miRNAs are essential for the regulation of the PI3K/AKT/FOXO pathway and receptor editing during B cell maturation.
Coffre, M. and Benhamou, D. and Riess, D. and Blumenberg, L. and Snetkova, V. and Hines, M.J. and Chakraborty, T. and Bajwa, S. and Jensen, K. and Chong, M.M.W. and Getu, L. and Silverman, G.J. and Blelloch, R. and Littman, D.R. and Calado, D. and Melamed, D. and Skok, J.A. and Rajewsky, K. and Koralov, S.B.
Cell Reports 17 (9): 2271-2285. 22 November 2016

Tracking transient conformational states of T4 lysozyme at room temperature combining X-ray crystallography and site-directed spin labeling.
Consentius, P. and Gohlke, U. and Loll, B. and Alings, C. and Mueller, R. and Heinemann, U. and Kaupp, M. and Wahl, M. and Risse, T.
Journal of the American Chemical Society 138 (39): 12868-12875. 5 October 2016

S100A4 in cancer metastasis: Wnt signaling-driven interventions for metastasis restriction.
Dahlmann, M. and Kobelt, D. and Walther, W. and Mudduluru, G. and Stein, U.
Cancers 8 (6): 59. 20 June 2016

Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily.
Daumke, O. and Praefcke, G.J.
Biopolymers 105 (8): 580-593. August 2016

Protein-mediated membrane remodeling.
Daumke, O. and Unger, V.M.
Journal of Structural Biology 196 (1): 1-2. October 2016

Interleukin-7 modulates anti-tumor CD8+ T cell responses via its action on host cells.
Deiser, K. and Stoycheva, D. and Bank, U. and Blankenstein, T. and Schüler, T.
PLoS ONE 11 (7): e0159690. 22 July 2016

The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3β interaction protein (GSKIP) regulates β-catenin through its interactions with both protein kinase A (PKA) and GSK3β.
Dema, A. and Schröter, M.F. and Perets, E. and Skroblin, P. and Moutty, M.C. and Deàk, V.A. and Birchmeier, W. and Klussmann, E.
Journal of Biological Chemistry 291 (37): 19618-19630. 9 September 2016

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E. and Herzog, S. and Labi, V. and Yasuda, T. and Köchert, K. and Janz, M. and Villunger, A. and Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5065-5070. 3 May 2016

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
Drachsler, M. and Kleber, S. and Mateos, A. and Volk, K. and Mohr, N. and Chen, S. and Cirovic, B. and Tuettenberg, J. and Gieffers, C. and Sykora, J. and Wirtz, C.R. and Mueller, W. and Synowitz, M. and Martin-Villalba, A.
Cell Death & Disease 7 : e2209. 28 April 2016

Epigenomic profiling of human CD4(+) T cells supports a linear differentiation model and highlights molecular regulators of memory development.
Durek, P. and Nordström, K. and Gasparoni, G. and Salhab, A. and Kressler, C. and de Almeida, M. and Bassler, K. and Ulas, T. and Schmidt, F. and Xiong, J. and Glažar, P. and Klironomos, F. and Sinha, A. and Kinkley, S. and Yang, X. and Arrigoni, L. and Amirabad, A.. and Ardakani, F.B. and Feuerbach, L. and Gorka, O. and Ebert, P. and Müller, F. and Li, N. and Frischbutter, S. and Schlickeiser, S. and Cendon, C. and Fröhler, S. and Felder, B. and Gasparoni, N. and Imbusch, C.D. and Hutter, B. and Zipprich, G. and Tauchmann, Y. and Reinke, S. and Wassilew, G. and Hoffmann, U. and Richter, A.S. and Sieverling, L. and Chang, H.D. and Syrbe, U. and Kalus, U. and Eils, J. and Brors, B. and Manke, T. and Ruland, J. and Lengauer, T. and Rajewsky, N. and Chen, W. and Dong, J. and Sawitzki, B. and Chung, H.R. and Rosenstiel, P. and Schulz, M.H. and Schultze, J.L. and Radbruch, A. and Walter, J. and Hamann, A. and Polansky, J.K.
Immunity 45 (5): 1148-1161. 15 November 2016

CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma.
Däbritz, J.H.M. and Yu, Y. and Milanovic, M. and Schönlein, M. and Rosenfeldt, M.T. and Dörr, J.R. and Kaufmann, A.M. and Dörken, B. and Schmitt, C.A.
Molecular Cancer Therapeutics 15 (5): 1074-1081. May 2016

Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes.
Ebstein, F. and Textoris-Taube, K. and Keller, C. and Golnik, R. and Vigneron, N. and Van den Eynde, B.J. and Schuler-Thurner, B. and Schadendorf, D. and Lorenz, F.K.M. and Uckert, W. and Urban, S. and Lehmann, A. and Albrecht-Koepke, N. and Janek, K. and Henklein, P. and Niewienda, A. and Kloetzel, P.M. and Mishto, M.
Scientific Reports 6 : 24032. 6 April 2016

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. and Czajkowski, M.T. and Barth, C. and Müller, P.M. and McShane, E. and Grunwald, S. and Beaudette, P. and Mecklenburg, N. and Volkmer, R. and Zühlke, K. and Dittmar, G. and Selbach, M. and Hammes, A. and Daumke, O. and Klussmann, E. and Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak and augments drug response.
Einsele-Scholz, S. and Malmsheimer, S. and Bertram, K. and Stehle, D. and Johaenning, J. and Manz, M. and Daniel, P.T. and Gillissen, B.F. and Schulze-Osthoff, K. and Essmann, F.
Journal of Cell Science 129 (11): 2213-2223. 1 June 2016

The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A. and Balduini, C. and Brand, A. and Coiffier, B. and Cordonnier, C. and Doehner, H. and Duyvene' de Wit, T. and Eichinger, S. and Fibbe, W. and Green, T. and de Haas, F. and Iolascon, A. and Jaffredo, T. and Rodeghiero, F. and Salles, G. and Schuringa, J.J.
Haematologica 101 (2): 115-208. February 2016

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Fabian, J. and Opitz, D. and Althoff, K. and Lodrini, M. and Hero, B. and Volland, R. and Beckers, A. and de Preter, K. and Decock, A. and Patil, N. and Abba, M. and Kopp-Schneider, A. and Astrahantseff, K. and Wünschel, J. and Pfeil, S. and Ercu, M. and Künkele, A. and Hu, J. and Thole, T. and Schweizer, L. and Mechtersheimer, G. and Carter, D. and Cheung, B.B. and Popanda, O. and von Deimling, A. and Koster, J. and Versteeg, R. and Schwab, M. and Marshall, G.M. and Speleman, F. and Erb, U. and Zoeller, M. and Allgayer, H. and Simon, T. and Fischer, M. and Kulozik, A.E. and Eggert, A. and Witt, O. and Schulte, J.H. and Deubzer, H.E.
Oncotarget 7 (41): 66344-66359. 11 October 2016

Detecting markers of therapy-induced senescence in cancer cells.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1534 : 41-52. 4 November 2016

A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis.
Fang, L. and Zhu, Q. and Neuenschwander, M. and Specker, E. and Wulf-Goldenberg, A. and Weis, W.I. and von Kries, J.P. and Birchmeier, W.
Cancer Research 76 (4): 891-901. 15 February 2016

Immunological memory: lessons from the past and a look to the future.
Farber, D.L. and Netea, M.G. and Radbruch, A. and Rajewsky, K. and Zinkernagel, R.M.
Nature Reviews Immunology 16 (2): 124-128. February 2016

The translational potential of microRNAs as biofluid markers of urological tumours.
Fendler, A. and Stephan, C. and Yousef, G.M. and Kristiansen, G. and Jung, K.
Nature Reviews Urology 13 (12): 734-752. December 2016

SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin.
Ferone, G. and Song, J.Y. and Sutherland, K.D. and Bhaskaran, R. and Monkhorst, K. and Lambooij, J.P. and Proost, N. and Gargiulo, G. and Berns, A.
Cancer Cell 30 (4): 519-532. 10 October 2016

Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL network phase II trial.
Ferrero, S. and Pastore, A. and Scholz, C.W. and Forstpointner, R. and Pezzutto, A. and Bergmann, L. and Truemper, L. and Finke, J. and Keller, U. and Ghione, P. and Passera, R. and Hiddemann, W. and Weigert, O. and Unterhalt, M. and Dreyling, M.
Leukemia 30 (4): 984-987. April 2016

DC generation from peripheral blood mononuclear cells in patients with chronic myeloid leukemia: Influence of interferons on DC yield and functional properties.
Floercken, A. and Kopp, J. and Kölsch, U. and Meisel, C. and Dörken, B. and Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 12 (5): 1117-1123. 3 May 2016

Polycomb and lung cancer: when the dosage makes the (kind of) poison.
Gargiulo, G. and Citterio, E. and Serresi, M.
Molecular & Cellular Oncology 3 (3): e1152345. May 2016

TERT core promotor mutations in early-onset bladder cancer.
Giedl, J. and Rogler, A. and Wild, A. and Riener, M.O. and Filbeck, T. and Burger, M. and Ruemmele, P. and Hurst, C. and Knowles, M. and Hartmann, A. and Zinnall, U. and Stoehr, R.
Journal of Cancer 7 (8): 915-920. 7 May 2016

Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells.
Gogol-Döring, A. and Ammar, I. and Gupta, S. and Bunse, M. and Miskey, C. and Chen, W. and Uckert, W. and Schulz, T.F. and Izsvák, Z. and Ivics, Z.
Molecular Therapy 24 (3): 592-606. March 2016

CancerResource - updated database of cancer-relevant proteins, mutations and interacting drugs.
Gohlke, B.O. and Nickel, J. and Otto, R. and Dunkel, M. and Preissner, R.
Nucleic Acids Research 44 (D1): D932-D937. 4 January 2016

Splenic marginal zone granulocytes acquire an accentuated neutrophil B cell-helper phenotype in chronic lymphocytic leukemia.
Gätjen, M. and Brand, F. and Grau, M. and Gerlach, K. and Kettritz, R. and Westermann, J. and Anagnostopoulos, I. and Lenz, P. and Lenz, G. and Höpken, U.E. and Rehm, A.
Cancer Research 76 (18): 5253-5265. 15 September 2016

AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Götz, F. and Roske, Y. and Schulz, M.S. and Autenrieth, K. and Bertinetti, D. and Faelber, K. and Zühlke, K. and Kreuchwig, A. and Kennedy, E. and Krause, G. and Daumke, O. and Herberg, F.W. and Heinemann, U. and Klussmann, E.
Biochemical Journal 473 (13): 1881-1894. 28 June 2016

Alternative splicing substantially diversifies the transcriptome during early photomorphogenesis and correlates with the energy availability in arabidopsis.
Hartmann, L. and Drewe-Boss, P. and Wiessner, T. and Wagner, G. and Geue, S. and Lee, H.C. and Obermueller, D.M. and Kahles, A. and Behr, J. and Sinz, F.H. and Raetsch, G. and Wachter, A.
Plant Cell 28 (11): 2715-2734. November 2016

ssHMM: Extracting intuitive sequence-structure motifs from high-throughput RNA-binding protein data.
Heller, D. and Krestel, R. and Ohler, U. and Vingron, M. and Marsico, A.
bioRxiv : 076034. 11 October 2016

DNA damage signaling instructs polyploid macrophage fate in granulomas.
Herrtwich, L. and Nanda, I. and Evangelou, K. and Nikolova, T. and Horn, V. and Sagar, and Erny, D. and Stefanowski, J. and Rogell, L. and Klein, C. and Gharun, K. and Follo, M. and Seidl, M. and Kremer, B. and Münke, N. and Senges, J. and Fliegauf, M. and Aschman, T. and Pfeifer, D. and Sarrazin, S. and Sieweke, M.H. and Wagner, D. and Dierks, C. and Haaf, T. and Ness, T. and Zaiss, M.M. and Voll, R.E. and Deshmukh, S.D. and Prinz, M. and Goldmann, T. and Hölscher, C. and Hauser, A.E. and Lopez-Contreras, A.J. and Grün, D. and Gorgoulis, V. and Diefenbach, A. and Henneke, P. and Triantafyllopoulou, A.
Cell 167 (5): 1264-1280. 17 November 2016

Detection of signature volatiles for cariogenic microorganisms.
Hertel, M. and Preissner, R. and Gillissen, B. and Schmidt-Westhausen, A.M. and Paris, S. and Preissner, S.
European Journal of Clinical Microbiology & Infectious Diseases 35 (2): 235-244. February 2016

Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis.
Hsu, P.Y. and Calviello, L. and Wu, H.Y.L. and Li, F.W. and Rothfels, C.J. and Ohler, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 113 (45): E7126-E7135. 8 November 2016

Delivery of therapeutics targeting the mRNA-binding protein HuR using 3DNA nanocarriers suppresses ovarian tumor growth.
Huang, Y.H. and Peng, W. and Furuuchi, N. and Gerhart, J. and Rhodes, K. and Mukherjee, N. and Jimbo, M. and Gonye, G.E. and Brody, J.R. and Getts, R.C. and Sawicki, J.A.
Cancer Research 76 (6): 1549-1559. 15 March 2016

MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer.
Ilm, K. and Fuchs, S. and Mudduluru, G. and Stein, U.
Oncotarget 7 (33): 53443-53458. 16 August 2016

Automated annotation and evaluation of in-source mass spectra in GC/atmospheric pressure chemical ionization-MS-based metabolomics.
Jaeger, C. and Hoffmann, F. and Schmitt, C.A. and Lisec, J.
Analytical Chemistry 88 (19): 9386-9390. 4 October 2016

Longitudinal study to assess the clinical significance of MSI2 expression in chronic myeloid keukemia patients.
Kaeda, J. and Ringel, F. and Oberender, C. and Gresse, M. and Amini, L. and Schwarz, M. and Doerken, B. and le Coutre, P.
Acta Haematologica 136 (1): 62-64. June 2016

Genome wide conditional mouse knockout resources.
Kaloff, C. and Anastassiadis, K. and Ayadi, A. and Baldock, R. and Beig, J. and Birling, M.C. and Bradley, A. and Brown, S.D.M. and Buerger, A. and Bushell, W. and Chiani, F. and Collins, F.S. and Doe, B. and Eppig, J.T. and Finnell, R.H. and Fletcher, C. and Flicek, P. and Fray, M. and Friedel, R.H. and Gambadoro, A. and Gates, H. and Hansen, J. and Herault, Y. and Hicks, G.G. and Hoerlein, A. and Hrabe de Angelis, M. and Iyer, V. and de Jong, P.J. and Koscielny, G. and Kuehn, R. and Liu, P. and Lloyd, K.C.K and Lopez, R.G. and Marschall, S. and Martinez, S. and McKerlie, C. and Meehan, T. and von Melchner, H. and Moore, M. and Murray, S.A. and Nagy, A. and Nutter, L.M.J. and Pavlovic, G. and Pombero, A. and Prosser, H. and Ramirez-Solis, R. and Ringwald, M. and Rosen, B. and Rosenthal, N. and Rossant, J. and Ruiz Noppinger, P. and Ryder, E. and Skarnes, W.C. and Schick, J. and Schnuetgen, F. and Schofield, P. and Seisenberger, C. and Selloum, M. and Smedley, D. and Simpson, E.M. and Stewart, A.F. and Teboul, L. and Tocchini Valentini, G.P. and Valenzuela, D. and West, A.P. and Wurst, W.
Drug Discovery Today: Disease Models 20 : 3-12. 2016

M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation.
Kandalla, P.K. and Sarrazin, S. and Molawi, K. and Berruyer, C. and Redelberger, D. and Favel, A. and Bordi, C. and de Bentzmann, S. and Sieweke, M.H.
Journal of Experimental Medicine 213 (11): 2269-2279. 10 October 2016

Bacteriophage tailspikes and bacterial O-antigens as a model system to study weak-affinity protein-polysaccharide interactions.
Kang, Y. and Gohlke, U. and Engström, O. and Hamark, C. and Scheidt, T. and Kunstmann, S. and Heinemann, U. and Widmalm, G. and Santer, M. and Barbirz, S.
Journal of the American Chemical Society 138 (29): 9109-9118. 27 July 2016

Cseq-simulator: a data simulator for CLIP-Seq experiments.
Kassuhn, W. and Ohler, U. and Drewe, P.
In: Pacific Symposium on Biocomputing (PSB) 2016, 4-8 Jan 2016, The Big Island of Hawaii, USA. January 2016

Regional regulation of filiform tongue papillae development by Ikkα/Irf6.
Kawasaki, M. and Kawasaki, K. and Oommen, S. and Blackburn, J. and Watanabe, M. and Nagai, T. and Kitamura, A. and Maeda, T. and Liu, B. and Schmidt-Ullrich, R. and Akiyama, T. and Inoue, J.I. and Hammond, N.L. and Sharpe, P.T. and Ohazama, A.
Developmental Dynamics 245 (9): 937-946. September 2016

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity.
Kieback, E. and Hilgenberg, E. and Stervbo, U. and Lampropoulou, V. and Shen, P. and Bunse, M. and Jaimes, Y. and Boudinot, P. and Radbruch, A. and Klemm, U. and Kühl, A.A. and Liblau, R. and Hoevelmeyer, N. and Anderton, S.M. and Uckert, W. and Fillatreau, S.
Immunity 44 (5): 1114-1126. 17 May 2016

B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice.
Knittel, G. and Liedgens, P. and Korovkina, D. and Seeger, J.M. and Al-Baldawi, Y. and Al-Maarri, M. and Fritz, C. and Vlantis, K. and Bezhanova, S. and Scheel, A.H. and Wolz, O.O. and Reimann, M. and Möller, P. and López, C. and Schlesner, M. and Lohneis, P. and Weber, A.N.R. and Trümper, L. and Staudt, L.M. and Ortmann, M. and Pasparakis, M. and Siebert, R. and Schmitt, C.A. and Klatt, A.R. and Wunderlich, F.T. and Schäfer, S.C. and Persigehl, T. and Montesinos-Rongen, M. and Odenthal, M. and Büttner, R. and Frenzel, L.P. and Kashkar, H. and Reinhardt, H.C.
Blood 127 (22): 2732-2741. 2 June 2016

Phase II trial of temsirolimus for relapsed/refractory primary CNS lymphoma.
Korfel, A. and Schlegel, U. and Herrlinger, U. and Dreyling, M. and Schmidt, C. and von Baumgarten, L. and Pezzutto, A. and Grobosch, T. and Kebir, S. and Thiel, E. and Martus, P. and Kiewe, P.
Journal of Clinical Oncology 34 (15): 1757-1763. 20 May 2016

Functional interaction of CCAAT/enhancer-binding-protein-α basic region mutants with E2F transcription factors and DNA.
Kowenz-Leutz, E. and Schuetz, A. and Liu, Q. and Knoblich, M. and Heinemann, U. and Leutz, A.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1859 (7): 841-847. July 2016

MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.
Krause, C.J. and Popp, O. and Thirunarayanan, N. and Dittmar, G. and Lipp, M. and Mueller, G.
Oncotarget 7 (9): 10414-10432. 1 March 2016

Tomo-seq: A method to obtain genome-wide expression data with spatial resolution.
Kruse, F. and Junker, J.P. and van Oudenaarden, A. and Bakkers, J.
Methods in Cell Biology 135 : 299-307. 2016

Neutropenic sepsis in the ICU: Outcome predictors in a two-phase model and microbiology findings.
Kruse, J.M. and Jenning, T. and Rademacher, S. and Arnold, R. and Schmitt, C.A. and Jörres, A. and Enghard, P. and Oppert, M.
Critical Care Research and Practice 2016 : 8137850. 2016

TALENs : Methods and Protocols.
Kuehn, R. and Wurst, W. and Wefers, B.
Methods in Molecular Biology, 1338 . Springer, New York. ISBN 978-1-4939-2931-3 2016

Divergent transcription and epigenetic directionality of human promoters.
Lacadie, S.A. and Ibrahim, M.M. and Gokhale, S.A. and Ohler, U.
FEBS Journal 283 (23): 4214-4222. December 2016

A comprehensive comparison of general RNA-RNA interaction prediction methods.
Lai, D. and Meyer, I.M.
Nucleic Acids Research 44 (7): e61. 20 April 2016

Eradication of large solid tumors by gene therapy with a T cell receptor targeting a single cancer-specific point mutation.
Leisegang, M. and Engels, B. and Schreiber, K. and Yew, P.Y. and Kiyotani, K. and Idel, C. and Arina, A. and Duraiswamy, J. and Weichselbaum, R.R. and Uckert, W. and Nakamura, Y. and Schreiber, H.
Clinical Cancer Research 22 (11): 2734-2743. 1 June 2016

Targeting human melanoma neoantigens by T cell receptor gene therapy.
Leisegang, M. and Kammertoens, T. and Uckert, W. and Blankenstein, T.
Journal of Clinical Investigation 126 (3): 854-858. 1 March 2016

MACC1 induces tumor progression in transgenic mice and colorectal cancer patients via increased pluripotency markers Nanog and Oct4.
Lemos, C. and Hardt, M.S. and Juneja, M. and Voss, C. and Foerster, S. and Jerchow, B. and Haider, W. and Blaker, H. and Stein, U.
Clinical Cancer Research 22 (11): 2812-2824. 1 June 2016

Survival of Igα-deficient mature B cells requires BAFF-R function.
Levit-Zerdoun, E. and Becker, M. and Pohlmeyer, R. and Wilhelm, I. and Maity, P.C. and Rajewsky, K. and Reth, M. and Hobeika, E.
Journal of Immunology 196 (5): 2348-2360. 1 March 2016

High-resolution expression map of the arabidopsis root reveals alternative splicing and lincRNA regulation.
Li, S. and Yamada, M. and Han, X. and Ohler, U. and Benfey, P.N.
Developmental Cell 39 (4): 508-522. 21 November 2016

Lowered pH leads to fusion peptide release and a highly dynamic intermediate of influenza hemagglutinin.
Lin, X.C. and Noel, J.K. and Wang, Q.H. and Ma, J.P. and Onuchic, J.N.
Journal of Physical Chemistry B 120 (36): 9654-9660. 15 September 2016

Extending the dynamic range in metabolomics experiments by automatic correction of peaks exceeding the detection limit.
Lisec, J. and Hoffmann, F. and Schmitt, C. and Jaeger, C.
Analytical Chemistry 88 (15): 7487-7492. 2 August 2016

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D. and Pahuja, A. and Geers-Knörr, C. and Scheibe, R. and Nowak, M. and Hamati, J. and Köhncke, C. and Purfürst, B. and Kanashova, T. and Schmidt, S. and Glass, D.J. and Morano, I. and Heuser, A. and Kraft, T. and Bassel-Duby, R. and Olson, E.N. and Dittmar, G. and Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180. May 2016

Minichromosome maintenance complex is a critical node in the miR-183 signaling network of MYCN-amplified neuroblastoma cells.
Lodrini, M. and Poschmann, G. and Schmidt, V. and Wünschel, J. and Dreidax, D. and Witt, O. and Höfer, T. and Meyer, H.E. and Stühler, K. and Eggert, A. and Deubzer, H.E.
Journal of Proteome Research 15 (7): 2178-2186. 1 July 2016

Different promoter affinities account for specificity in MYC-dependent gene regulation.
Lorenzin, F. and Benary, U. and Baluapuri, A. and Walz, S. and Jung, L.A. and von Eyss, B. and Kisker, C. and Wolf, J. and Eilers, M. and Wolf, E.
eLife 5 : e15161. 27 July 2016

Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients.
Lu, H. and Busch, J. and Jung, M. and Rabenhorst, S. and Ralla, B. and Kilic, E. and Mergemeier, S. and Budach, N. and Fendler, A. and Jung, K.
Clinica Chimica Acta 452 : 109-119. 15 January 2016

Breaking TADs: how alterations of chromatin domains result in disease.
Lupiáñez, D.G. and Spielmann, M. and Mundlos, S.
Trends in Genetics 32 (4): 225-237. April 2016

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri, L. and Noerenberg, D. and Young, E. and Mylonas, E. and Abdulla, M. and Frick, M. and Asmar, F. and Ljungstroem, V. and Schneider, M. and Yoshida, K. and Skaftason, A. and Pandzic, T. and Gonzalez, B. and Tasidou, A. and Waldhueter, N. and Rivas-Delgado, A. and Angelopoulou, M. and Ziepert, M. and Arends, C.M. and Couronne, L. and Lenze, D. and Baldus, C.D. and Bastard, C. and Okosun, J. and Fitzgibbon, J. and Doerken, B. and Drexler, H.G. and Roos-Weil, D. and Schmitt, C.A. and Munch-Petersen, H.D. and Zenz, T. and Hansmann, M.L. and Strefford, J.C. and Enblad, G. and Bernard, O.A. and Ralfkiaer, E. and Erlanson, M. and Korkolopoulou, P. and Hultdin, M. and Papadaki, T. and Gronbaek, K. and Lopez-Guillermo, A. and Ogawa, S. and Kueppers, R. and Stamatopoulos, K. and Stavroyianni, N. and Kanellis, G. and Rosenwald, A. and Campo, E. and Amini, R.M. and Ott, G. and Vassilakopoulos, T.P. and Hummel, M. and Rosenquist, R. and Damm, F.
Blood 128 (23): 2666-2670. 15 December 2016

A complex water network contributes to high-affinity binding in an antibody-antigen interface.
Marino, S.F. and Olal, D. and Daumke, O.
Data in Brief 6 : 394-397. March 2016

Tubular epithelial NF-κB activity regulates ischemic AKI.
Markó, L. and Vigolo, E. and Hinze, C. and Park, J.K. and Roël, G. and Balogh, A. and Choi, M. and Wübken, A. and Cording, J. and Blasig, I.E. and Luft, F.C. and Scheidereit, C. and Schmidt-Ott, K.M. and Schmidt-Ullrich, R. and Müller, D.N.
Journal of the American Society of Nephrology 27 (9): 2658-2669. September 2016

Microglia development follows a stepwise program to regulate brain homeostasis.
Matcovitch-Natan, O. and Winter, D.R. and Giladi, A. and Vargas Aguilar, S. and Spinrad, A. and Sarrazin, S. and Ben-Yehuda, H. and David, E. and Zelada González, F. and Perrin, P. and Keren-Shaul, H. and Gury, M. and Lara-Astaiso, D. and Thaiss, C.A. and Cohen, M. and Bahar Halpern, K. and Baruch, K. and Deczkowska, A. and Lorenzo-Vivas, E. and Itzkovitz, S. and Elinav, E. and Sieweke, M.H. and Schwartz, M. and Amit, I.
Science 353 (6301): aad8670. 19 August 2016

Hodgkin lymphoma: pathology and biology.
Mathas, S. and Hartmann, S. and Küppers, R.
Seminars in Hematology 53 (3): 139-147. July 2016

Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA.
Mensali, N. and Ying, F. and Sheng, V.O.Y. and Yang, W. and Walseng, E. and Kumari, S. and Fallang, L.E. and Kolstad, A. and Uckert, W. and Malmberg, K.J. and Waelchli, S. and Olweus, J.
OncoImmunology 5 (5): e1138199. 18 February 2016

Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Moenke, G. and Cristiano, E. and Finzel, A. and Friedrich, D. and Herzel, H. and Falcke, M. and Loewer, A.
bioRxiv : 068668. 28 November 2016

Effects of silibinin on growth and invasive properties of human ovarian carcinoma cells through suppression of heregulin/HER3 pathway.
Momeny, M. and Ghasemi, R. and Valenti, G. and Miranda, M. and Zekri, A. and Zarrinrad, G. and Javadikooshesh, S. and Yaghmaie, M. and Alimoghaddam, K. and Ghavamzadeh, A. and Ghaffari, S.H.
Tumor Biology 37 (3): 3913-3923. March 2016

Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets.
Mudduluru, G. and Walther, W. and Kobelt, D. and Dahlmann, M. and Treese, C. and Assaraf, Y.G. and Stein, U.
Drug Resistance Updates 26 : 10-27. May 2016

Integrative classification of human coding and non-coding genes based on RNA metabolism profiles.
Mukherjee, N. and Calviello, L. and Hirsekorn, A. and de Pretis, S. and Pelizzola, M. and Ohler, U.
bioRxiv : 073643. 6 September 2016

Diagnostik, Therapie und Verlaufskontrolle des Diabetes mellitus im Kindes- und Jugendalter - AWMF-Registernummer 057-016 [Diagnosis, therapy and follow-up of diabetes mellitus in children and adolescents - AWMF-Registry-Number 057-016].
Neu, A. and Buerger-Buesing, J. and Danne, T. and Dost, A. and Holder, M. and Holl, R.W. and Holterhus, P.M. and Kapellen, T. and Karges, B. and Kordonouri, O. and Mueller, S. and Raile, K. and Schweizer, R. and von Sengbusch, S. and Stachow, R. and Wagner, V. and Wiegand, S. and Ziegler, R.
Diabetologie und Stoffwechsel 11 (1): 35-94. 25 February 2016

BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features.
Neuendorff, N.R. and Burmeister, T. and Doerken, B. and Westermann, J.
Annals of Hematology 95 (8): 1211-1221. August 2016

CCL4 as an adjuvant for DNA vaccination in a Her2/neu mouse tumor model.
Nguyen-Hoai, T. and Pham-Duc, M. and Gries, M. and Dörken, B. and Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 23 (6): 162-167. June 2016

SMOG 2: A versatile software package for generating structure-based models.
Noel, J.K. and Levi, M. and Raghunathan, M. and Lammert, H. and Hayes, R.L. and Onuchic, J.N. and Whitford, P.C.
PLoS Computational Biology 12 (3): e1004794. 10 March 2016

Sequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamics.
Noel, J.K. and Morcos, F. and Onuchic, J.N.
F1000 Research 5 (F1000 Faculty Rev): 106. 26 January 2016

How EF-Tu can contribute to efficient proofreading of aa-tRNA by the ribosome.
Noel, J.K. and Whitford, P.C.
Nature Communications 7 : 13314. 31 October 2016

Structure of the hantavirus nucleoprotein provides insights into the mechanism of RNA encapsidation.
Olal, D. and Daumke, O.
Cell Reports 14 (9): 2092-2099. 8 March 2016

Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.
Orlanski, S. and Labi, V. and Reizel, Y. and Spiro, A. and Lichtenstein, M. and Levin-Klein, R. and Koralov, S.B. and Skversky, Y. and Rajewsky, K. and Cedar, H. and Bergman, Y.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5018-5023. 3 May 2016

Improved treatment of MT-3 breast cancer and brain metastases in a mouse xenograft by LRP-targeted oxaliplatin liposomes.
Orthmann, A. and Peiker, L. and Fichtner, I. and Hoffmann, A. and Hilger, R.A. and Zeisig, R.
Journal of Biomedical Nanotechnology 12 (1): 56-68. January 2016

Vectors and strategies for nonviral cancer gene therapy.
Pahle, J. and Walther, W.
Expert Opinion on Biological Therapy 16 (4): 443-461. April 2016

Bacterial toxins for oncoleaking suicidal cancer gene therapy.
Pahle, J. and Walther, W.
Recent Results in Cancer Research 209 : 95-110. 2016

A complex of Htm1 and the oxidoreductase Pdi1 accelerates degradation of misfolded glycoproteins.
Pfeiffer, A. and Stephanowitz, H. and Krause, E. and Volkwein, C. and Hirsch, C. and Jarosch, E. and Sommer, T.
Journal of Biological Chemistry 291 (23): 12195-12207. 3 June 2016

Impact of anti-PEG IgM antibodies on the pharmacokinetics of pegylated asparaginase preparations in mice.
Poppenborg, S.M. and Wittmann, J. and Walther, W. and Brandenburg, G. and Kraehmer, R. and Baumgart, J. and Leenders, F.
European Journal of Pharmaceutical Sciences 91 : 122-130. 25 August 2016

Immune modulation and prevention of autoimmune disease by repeated sequences from parasites linked to self antigens.
Puentes, F. and Dickhaut, K. and Hofstaetter, M. and Pfeil, J. and Lauer, U. and Hamann, A. and Hoffmann, U. and Falk, K. and Roetzschke, O.
Journal of Neuroimmune Pharmacology 11 (4): 749-762. December 2016

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Qi, J. and Yu, Y. and Akilli Öztürk, Ö. and Holland, J.D. and Besser, D. and Fritzmann, J. and Wulf-Goldenberg, A. and Eckert, K. and Fichtner, I. and Birchmeier, W.
Gut 65 (10): 1690-1701. October 2016

C/EBPβ regulates homeostatic and oncogenic gastric cell proliferation.
Regalo, G. and Förster, S. and Resende, C. and Bauer, B. and Fleige, B. and Kemmner, W. and Schlag, P.M. and Meyer, T.F. and Machado, J.C. and Leutz, A.
Journal of Molecular Medicine 94 (12): 1385-1395. December 2016

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors.
Richter, M. and Saydaminova, K. and Yumul, R. and Krishnan, R. and Liu, J. and Nagy, E.E. and Singh, M. and Izsvák, Z. and Cattaneo, R. and Uckert, W. and Palmer, D. and Ng, P. and Haworth, K.G. and Kiem, H.P. and Ehrhardt, A. and Papayannopoulou, T. and Lieber, A.
Blood 128 (18): 2206-2217. 3 November 2016

Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.
Riemke, P. and Czeh, M. and Fischer, J. and Walter, C. and Ghani, S. and Zepper, M. and Agelopoulos, K. and Lettermann, S. and Gebhardt, M.L. and Mah, N. and Weilemann, A. and Grau, M. and Groening, V. and Haferlach, T. and Lenze, D. and Delwel, R. and Prinz, M. and Andrade-Navarro, M.A. and Lenz, G. and Dugas, M. and Mueller-Tidow, C. and Rosenbauer, F.
EMBO Journal 35 (22): 2399-2416. 15 November 2016

OpenMS: a flexible open-source software platform for mass spectrometry data analysis.
Roest, H.L. and Sachsenberg, T. and Aiche, S. and Bielow, C. and Weisser, H. and Aicheler, F. and Andreotti, S. and Ehrlich, H.C. and Gutenbrunner, P. and Kenar, E. and Liang, X. and Nahnsen, S. and Nilse, L. and Pfeuffer, J. and Rosenberger, G. and Rurik, M. and Schmitt, U. and Veit, J. and Walzer, M. and Wojnar, D. and Wolski, W.E. and Schilling, O. and Choudhary, J.S. and Malmstroem, L. and Aebersold, R. and Reinert, K. and Kohlbacher, O.
Nature Methods 13 (9): 741-748. September 2016

Eosinophils and mast cells: a lineage apart.
Sarrazin, S. and Sieweke, M.H.
Nature Immunology 17 (6): 609-611. 19 May 2016

Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity.
Schirmer, D. and Grünewald, T.G.P. and Klar, R. and Schmidt, O. and Wohlleber, D. and Rubio, R.A. and Uckert, W. and Thiel, U. and Bohne, F. and Busch, D.H. and Krackhardt, A.M. and Burdach, S. and Richter, G.H.S.
OncoImmunology 5 (6): e1175795. 25 April 2016

SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.
Schmid, F. and Wang, Q. and Huska, M.R. and Andrade-Navarro, M.A. and Lemm, M. and Fichtner, I. and Dahlmann, M. and Kobelt, D. and Walther, W. and Smith, J. and Schlag, P.M. and Stein, U.
Oncogene 35 (46): 5942-5952. 17 November 2016

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt, F. and Gasparoni, N. and Gasparoni, G. and Gianmoena, K. and Cadenas, C. and Polansky, J.K. and Ebert, P. and Nordstroem, K. and Barann, M. and Sinha, A. and Froehler, S. and Xiong, J. and Amirabad, A.D. and Ardakani, F.B. and Hutter, B. and Zipprich, G. and Felder, B. and Eils, J. and Brors, B. and Chen, W. and Hengstler, J.G. and Hamann, A. and Lengauer, T. and Rosenstiel, P. and Walter, J. and Schulz, M.H.
bioRxiv : 081935. 19 October 2016

The persistent dynamic secrets of senescence.
Schmitt, C.A.
Nature Cell Biology 18 (9): 913-915. September 2016

ANCA-associated vasculitis and the mechanisms of tissue injury.
Schreiber, A. and Choi, M.
In: Systemic Vasculitides: Current Status and Perspectives. Springer International Publishing, Switzerland, 141-158. ISBN 978-3-319-40134-8 14 October 2016

The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion.
Schulte, K. and Pawlowski, N. and Faelber, K. and Fröhlich, C. and Howard, J. and Daumke, O.
BMC Biology 14 (1): 14. 2 March 2016

ALVIS: interactive non-aggregative visualization and explorative analysis of multiple sequence alignments.
Schwarz, R.F. and Tamuri, A.U. and Kultys, M. and King, J. and Godwin, J. and Florescu, A.M. and Schultz, J. and Goldman, N.
Nucleic Acids Research 44 (8): e77. 5 May 2016

Polycomb repressive complex 2 is a barrier to KRAS-driven inflammation and epithelial-mesenchymal transition in non-small-cell lung cancer.
Serresi, M. and Gargiulo, G. and Proost, N. and Siteur, B. and Cesaroni, M. and Koppens, M. and Xie, H. and Sutherland, K.D. and Hulsman, D. and Citterio, E. and Orkin, S. and Berns, A. and van Lohuizen, M.
Cancer Cell 29 (1): 17-31. 11 January 2016

TAK1 adaptor proteins TAB2 and TAB3 link the signalosome to B cell receptor-induced IKK activation.
Shinohara, H. and Yasuda, T. and Kurosaki, T.
FEBS Letters 590 (18): 3264-3269. September 2016

Second-line treatment in pancreatic cancer patients: Who profits? Results from the CONKO study group.
Sinn, M. and Daelken, L. and Striefler, J.K. and Bischoff, S. and Schweitzer, N. and Pelzer, U. and Doerken, B. and Riess, H. and Stieler, J.M.
Pancreas 45 (4): 601-605. April 2016

Nikolai V. Timofeeff-Ressovsky and the Campus Berlin-Buch.
Sommer, T.
Genetics, Evolution and Radiation : ix-xi. 2016

Stefan Jentsch (1955-2016) Obituary.
Sommer, T. and Hoppe, T. and Rape, M.
Cell 167 (7): 1667-1668. 15 December 2016

Stefan Jentsch (1955-2016) Obituary.
Sommer, T. and Hoppe, T. and Rape, M.
Molecular Cell 64 (6): 1011-1012. 15 December 2016

Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells.
Soucie, E.L. and Weng, Z. and Geirsdóttir, L. and Molawi, K. and Maurizio, J. and Fenouil, R. and Mossadegh-Keller, N. and Gimenez, G. and VanHille, L. and Beniazza, M. and Favret, J. and Berruyer, C. and Perrin, P. and Hacohen, N. and Andrau, J.C. and Ferrier, P. and Dubreuil, P. and Sidow, A. and Sieweke, M.H.
Science 351 (6274): aad5510. 12 February 2016

XDSAPP2.0.
Sparta, K.M. and Krug, M. and Heinemann, U. and Mueller, U. and Weiss, M.S.
Journal of Applied Crystallography 49 (3): 1085-1092. June 2016

Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice.
Spielmann, M. and Kakar, N. and Tayebi, N. and Leettola, C. and Nürnberg, G. and Sowada, N. and Lupiáñez, D.G. and Harabula, I. and Flöttmann, R. and Horn, D. and Chan, W.L. and Wittler, L. and Yilmaz, R. and Altmüller, J. and Thiele, H. and van Bokhoven, H. and Schwartz, C.E. and Nürnberg, P. and Bowie, J.U. and Ahmad, J. and Kubisch, C. and Mundlos, S. and Borck, G.
Genome Research 26 (2): 183-191. February 2016

The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6.
Stauss, D. and Brunner, C. and Berberich-Siebelt, F. and Höpken, U.E. and Lipp, M. and Müller, G.
EMBO Journal 35 (8): 881-898. 15 April 2016

Comprehensive small RNA-Seq of adeno-associated virus (AAV)-infected human cells detects patterns of novel, non-coding AAV RNAs in the absence of cellular miRNA regulation.
Stutika, C. and Mietzsch, M. and Gogol-Doering, A. and Weger, S. and Sohn, M. and Chen, W. and Heilbronn, R.
PLoS ONE 11 (9): e0161454. 9 September 2016

Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients.
Szasz, A.M. and Lanczky, A. and Nagy, A. and Foerster, S. and Hark, K. and Green, J.E. and Boussioutas, A. and Busuttil, R. and Szabo, A. and Gyorffy, B.
Oncotarget 7 (31): 49322-49333. 2 August 2016

Bone marrow GvHD after allogeneic hematopoietic stem cell transplantation.
Szyska, M. and Na, I.K.
Frontiers in Immunology 7 : 118. 30 March 2016

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
Tan, J. and Pieper, K. and Piccoli, L. and Abdi, A. and Foglierini, M. and Geiger, R. and Tully, C.M. and Jarrossay, D. and Ndungu, F.M. and Wambua, J. and Bejon, P. and Silacci Fregni, C. and Fernandez-Rodriguez, B. and Barbieri, S. and Bianchi, S. and Marsh, K. and Thathy, V. and Corti, D. and Sallusto, F. and Bull, P. and Lanzavecchia, A.
Nature 529 (7584): 105-109. 7 January 2016

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Textor, A. and Schmidt, K. and Kloetzel, P.M. and Weißbrich, B. and Perez, C. and Charo, J. and Anders, K. and Sidney, J. and Sette, A. and Schumacher, T.N.M. and Keller, C. and Busch, D.H. and Seifert, U. and Blankenstein, T.
Journal of Experimental Medicine 213 (11): 2333-2348. 17 October 2016

RNF4-dependent oncogene activation by protein stabilization.
Thomas, J.J. and Abed, M. and Heuberger, J. and Novak, R. and Zohar, Y. and Beltra-Lopez, A.P. and Trausch-Azar, J.S. and Ilagan, M.X.G. and Benhamou, D. and Dittmar, G. and Kopan, R. and Birchmeier, W. and Schwartz, A.L. and Orian, A.
Cell Reports 16 (12): 3388-3400. 20 September 2016

LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.
Tomann, P. and Paus, R. and Millar, S.E. and Scheidereit, C. and Schmidt-Ullrich, R.
Development 143 (9): 1512-1522. 1 May 2016

The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation.
Vučićević, D. and Gehre, M. and Dhamija, S. and Friis-Hansen, L. and Meierhofer, D. and Sauer, S. and Ørom, U.A.
Oncotarget 7 (23): 33934-33947. 7 June 2016

Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A. and Cohen, I. and Popp, O. and Dittmar, G. and Reiss, Y. and Sommer, T. and Ravid, T. and Jarosch, E.
Molecular Cell 63 (5): 827-839. 1 September 2016

Caspase-mediated apoptosis induction in zebrafish cerebellar Purkinje neurons.
Weber, T. and Namikawa, K. and Winter, B. and Müller-Brown, K. and Kühn, R. and Wurst, W. and Köster, R.W.
Development 143 (22): 4279-4287. 15 November 2016

Genome editing in mice using TALE nucleases.
Wefers, B. and Brandl, C. and Ortiz, O. and Wurst, W. and Kühn, R.
Methods in Molecular Biology 1338 : 229-243. 2016

Identifying RBP targets with RIP-seq.
Wessels, H.H. and Hirsekorn, A. and Ohler, U. and Mukherjee, N.
Methods in Molecular Biology 1358 : 141-152. 2016

The mRNA-bound proteome of the early fly embryo.
Wessels, H.H. and Imami, K. and Baltz, A.G. and Kolinksi, M. and Beldovskaya, A. and Selbach, M. and Small, S. and Ohler, U. and Landthaler, M.
Genome Research 26 (7): 1000-1009. July 2016

Comprehensive translational control of tyrosine kinase expression by upstream open reading frames.
Wethmar, K. and Schulz, J. and Muro, E.M. and Talyan, S. and Andrade-Navarro, M.A. and Leutz, A.
Oncogene 35 (13): 1736-1742. 31 March 2016

Dysregulated development of IL-17-and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORγt.
Wichner, K. and Stauss, D. and Kampfrath, B. and Krüger, K. and Müller, G. and Rehm, A. and Lipp, M. and Höpken, U.E.
FASEB Journal 30 (2): 761-774. February 2016

FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm, K. and Happel, K. and Eelen, G. and Schoors, S. and Oellerich, M.F. and Lim, R. and Zimmermann, B. and Aspalter, I.M. and Franco, C.A. and Boettger, T. and Braun, T. and Fruttiger, M. and Rajewsky, K. and Keller, C. and Brüning, J.C. and Gerhardt, H. and Carmeliet, P. and Potente, M.
Nature 529 (7585): 216-220. 14 January 2016

Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach.
Winter, A. and Sigurdardottir, A.G. and DiCara, D. and Valenti, G. and Blundell, T.L. and Gherardi, E.
Molecular Cancer Therapeutics 15 (1): 3-14. January 2016

Mouse model for acute Epstein-Barr virus infection.
Wirtz, T. and Weber, T. and Kracker, S. and Sommermann, T. and Rajewsky, K. and Yasuda, T.
Proceedings of the National Academy of Sciences of the United States of America 113 (48): 13821-13826. 29 November 2016

Spatially resolved genome-wide transcriptional profiling identifies BMP signaling as essential regulator of zebrafish cardiomyocyte regeneration.
Wu, C.C. and Kruse, F. and Vasudevarao, M.D. and Junker, J.P. and Zebrowski, D.C. and Fischer, K. and Noel, E.S. and Gruen, D. and Berezikov, E. and Engel, F.B. and van Oudenaarden, A. and Weidinger, G. and Bakkers, J.
Developmental Cell 36 (1): 36-49. 11 January 2016

Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation.
Xiao, M.S. and Zhang, B. and Li, Y.S. and Gao, Q. and Sun, W. and Chen, W.
Molecular Systems Biology 12 (12): 890. 8 December 2016

MAP kinase cascades in antigen receptor signaling and physiology.
Yasuda, T.
Current Topics in Microbiology and Immunology 393 : 211-231. 2016

RiboDiff: detecting changes of translation efficiency from ribosome footprints.
Zhong, Y. and Karaletsos, T. and Drewe, P. and Sreedharan, V. and Kuo, D. and Singh, K. and Wendel, H.G. and Raetsch, G.
bioRxiv : 017111. 11 January 2016

High-resolution in situ hybridization analysis on the chromosomal interval 61C7-61C8 of Drosophila melanogaster reveals interbands as open chromatin domains.
Zielke, T. and Glotov, A. and Saumweber, H.
Chromosoma 125 (3): 423-435. June 2016

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P. and Kaergel, E. and Heinig, M. and Fontaine, J.F. and Patone, G. and Muro, E.M. and Mathas, S. and Hummel, M. and Andrade-Navarro, M.A. and Hübner, N. and Scheidereit, C.
Genome Medicine 8 (1): 28. 17 March 2016

The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation.
von Delbrück, M. and Kniss, A. and Rogov, V.V. and Pluska, L. and Bagola, K. and Löhr, F. and Güntert, P. and Sommer, T. and Dötsch, V.
Molecular Cell 62 (6): 918-928. 16 June 2016

2015

Gab1 and Mapk signaling are essential in the hair cycle and hair follicle stem cell quiescence.
Akilli Öztürk, Ö. and Pakula, H. and Chmielowiec, J. and Qi, J. and Stein, S. and Lan, L. and Sasaki, Y. and Rajewsky, K. and Birchmeier, W.
Cell Reports 13 (3): 561-572. 20 October 2015

A rapid embryonic stem cell-based mouse model for B-cell lymphomas driven by Epstein-Barr virus protein LMP1.
Ba, Z. and Meng, F.L. and Gostissa, M. and Huang, P.Y. and Ke, Q. and Wang, Z. and Dao, M.N. and Fujiwara, Y. and Rajewsky, K. and Zhang, B. and Alt, F.W.
Cancer Immunology Research 3 (6): 641-649. June 2015

Suppression of peripheral pain by blockade of voltage-gated calcium 2.2 channels in nociceptors induces RANKL and impairs recovery from inflammatory arthritis in a mouse model.
Baddack, U. and Frahm, S. and Antolin-Fontes, B. and Grobe, J. and Lipp, M. and Mueller, G. and Ibanez-Tallon, I.
Arthritis & Rheumatology 67 (6): 1657-1667. June 2015

Cancer evolution: mathematical models and computational inference.
Beerenwinkel, N. and Schwarz, R.F. and Gerstung, M. and Markowetz, F.
Systematic Biology 64 (1): e1-e25. January 2015

Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K. and Goergen, H. and Hitz, F. and Zijlstra, J.M. and Greil, R. and Markova, J. and Sasse, S. and Fuchs, M. and Topp, M.S. and Soekler, M. and Mathas, S. and Meissner, J. and Wilhelm, M. and Koch, P. and Lindemann, H.W. and Schalk, E. and Semrau, R. and Kriz, J. and Vieler, T. and Bentz, M. and Lange, E. and Mahlberg, R. and Hassler, A. and Vogelhuber, M. and Hahn, D. and Mezger, J. and Krause, S.W. and Skoetz, N. and Böll, B. and von Tresckow, B. and Diehl, V. and Hallek, M. and Borchmann, P. and Stein, H. and Eich, H. and Engert, A.
Lancet 385 (9976): 1418-1427. 11 April 2015

Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia.
Berenstein, R. and Blau, I.W. and Suckert, N. and Baldus, C. and Pezzutto, A. and Dörken, B. and Blau, O.
Journal of Experimental & Clinical Cancer Research 34 (1): 55. 22 May 2015

Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region.
Berenstein, R. and Blau, O. and Nogai, A. and Waechter, M. and Slonova, E. and Schmidt-Hieber, M. and Kunitz, A. and Pezzutto, A. and Doerken, B. and Blau, I.W.
BMC Cancer 15 (1): 68. 18 February 2015

Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.
Blackburn, J. and Kawasaki, K. and Porntaveetus, T. and Kawasaki, M. and Otsuka-Tanaka, Y. and Miake, Y. and Ota, M.S. and Watanabe, M. and Hishinuma, M. and Nomoto, T. and Oommen, S. and Ghafoor, S. and Harada, F. and Nozawa-Inoue, K. and Maeda, T. and Peterkova, R. and Lesot, H. and Inoue, J. and Akiyama, T. and Schmidt-Ullrich, R. and Liu, B. and Hu, Y. and Page, A. and Ramirez, A. and Sharpe, P.T. and Ohazama, A.
Journal of Dental Research 94 (1): 121-128. January 2015

Targeting cancer-specific mutations by T cell receptor gene therapy.
Blankenstein, T. and Leisegang, M. and Uckert, W. and Schreiber, H.
Current Opinion in Immunology 33 : 112-119. April 2015

Visceral leishmaniasis diagnosis and reporting delays as an obstacle to timely response actions in Nepal and India.
Boettcher, J.P. and Siwakoti, Y. and Milojkovic, A. and Siddiqui, N.A. and Gurung, C.K. and Rijal, S. and Das, P. and Kroeger, A. and Banjara, M.R.
BMC Infectious Diseases 15 (1): 43. 6 February 2015

Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
Brandl, C. and Ortiz, O. and Röttig, B. and Wefers, B. and Wurst, W. and Kühn, R.
FEBS Open Bio 5 : 26-35. 2015

Circulating metastasis associated in colon cancer 1 transcripts in gastric cancer patient plasma as diagnostic and prognostic biomarker.
Burock, S. and Herrmann, P. and Wendler, I. and Niederstrasser, M. and Wernecke, K.D. and Stein, U.
World Journal of Gastroenterology 21 (1): 333-341. 7 January 2015

Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas.
Busch, J. and Ralla, B. and Jung, M. and Wotschofsky, Z. and Trujillo-Arribas, E. and Schwabe, P. and Kilic, E. and Fendler, A. and Jung, K.
Journal of Experimental & Clinical Cancer Research 34 (1): 61. 14 June 2015

Arabidopsis KCBP interacts with AIR9 but stays in the cortical division zone throughout mitosis via its MyTH4-FERM domain.
Buschmann, H. and Dols, J. and Kopischke, S. and Pena, E.J. and Andrade-Navarro, M.A. and Heinlein, M. and Szymanski, D.B. and Zachgo, S. and Doonan, J.H. and Lloyd, C.W.
Journal of Cell Science 28 (11): 2033-2046. 1 June 2015

Deregulation of the endogenous C/EBPβ LIP isoform predisposes to tumorigenesis.
Bégay, V. and Smink, J.J. and Loddenkemper, C. and Zimmermann, K. and Rudolph, C. and Scheller, M. and Steinemann, D. and Leser, U. and Schlegelberger, B. and Stein, H. and Leutz, A.
Journal of Molecular Medicine 93 (1): 39-49. January 2015

A spectral analysis approach to detect actively translated open reading frames in high-resolution ribosome profiling data.
Calviello, L. and Mukherjee, N. and Wyler, E. and Zauber, H. and Hirsekorn, A. and Selbach, M. and Landthaler, M. and Obermayer, B. and Ohler, U.
bioRxiv : 031625. 13 November 2015

Identification of 2-[4-[(4-methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers.
Cheng, X. and Dimou, E. and Alborzinia, H. and Wenke, F. and Goehring, A. and Reuter, S. and Mah, N. and Fuchs, H. and Andrade-Navarro, M.A. and Adjaye, J. and Gul, S. and Harms, C. and Utikal, J. and Klipp, E. and Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58 (12): 4976-4983. 25 June 2015

Ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4.
Cheng, X. and Yoshida, H. and Raoofi, D. and Saleh, S. and Alborzinia, H. and Wenke, F. and Goehring, A. and Reuter, S. and Mah, N. and Fuchs, H.R. and Andrade-Navarro, M.A. and Adjaye, J. and Gul, S. and Utikal, J. and Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58 (1): 5742-5750. 13 August 2015

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu, V.T. and Weber, T. and Wefers, B. and Wurst, W. and Sander, S. and Rajewsky, K. and Kühn, R.
Nature Biotechnology 33 (5): 543-548. May 2015

Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
Chumduri, C. and Gillissen, B. and Richter, A. and Richter, A. and Milojkovic, A. and Overkamp, T. and Mueller, A. and Pott, C. and Daniel, P.T.
Journal of Molecular Medicine 93 (5): 559-572. May 2015

RNA interference for antimetastatic therapy.
Dahlmann, M. and Stein, U.
Methods in Molecular Biology 1317 : 153-165. 2015

T cells engineered to express a T-cell receptor specific for glypican-3 recognize and kill hepatoma cells in vitro and in mice.
Dargel, C. and Bassani-Sternberg, M. and Hasreiter, J. and Zani, F. and Bockmann, J.H. and Thiele, F. and Bohne, F. and Wisskirchen, K. and Wilde, S. and Sprinzl, M.F. and Schendel, D.J. and Krackhardt, A.M. and Uckert, W. and Wohlleber, D. and Schiemann, M. and Stemmer, K. and Heikenwälder, M. and Busch, D.H. and Richter, G. and Mann, M. and Protzer, U.
Gastroenterology 149 (4): 1042-1052. October 2015

Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.
Dick, A. and Graf, L. and Olal, D. and von der Malsburg, A. and Gao, S. and Kochs, G. and Daumke, O.
Journal of Biological Chemistry 290 (20): 12779-12792. 15 May 2015

Perspectives on unidirectional versus divergent transcription.
Duttke, S.H.C. and Lacadie, S.A. and Ibrahim, M.M. and Glass, C.K. and Corcoran, D.L. and Benner, C. and Heinz, S. and Kadonaga, J.T. and Ohler, U.
Molecular Cell 60 (3): 348-349. 5 November 2015

Human promoters are intrinsically directional.
Duttke, S.H.C. and Lacadie, S.A. and Ibrahim, M.M. and Glass, C.K. and Corcoran, D.L. and Benner, C. and Heinz, S. and Kadonaga, J.T. and Ohler, U.
Molecular Cell 57 (4): 674-684. 19 February 2015

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Ecker, J. and Oehme, I. and Mazitschek, R. and Korshunov, A. and Kool, M. and Hielscher, T. and Kiss, J. and Selt, F. and Konrad, C. and Lodrini, M. and Deubzer, H.E. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Witt, O. and Milde, T.
Acta Neuropathologica Communications 3 : 22. 3 April 2015

Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Finkin, S. and Yuan, D. and Stein, I. and Taniguchi, K. and Weber, A. and Unger, K. and Browning, J.L. and Goossens, N. and Nakagawa, S. and Gunasekaran, G. and Schwartz, M.E. and Kobayashi, M. and Kumada, H. and Berger, M. and Pappo, O. and Rajewsky, K. and Hoshida, Y. and Karin, M. and Heikenwalder, M. and Ben-Neriah, Y. and Pikarsky, E.
Nature Immunology 16 (12): 1235-1244. December 2015

Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken, A. and Grau, M. and Wolf, A. and Weilemann, A. and Kopp, J. and Dörken, B. and Blankenstein, T. and Pezzutto, A. and Lenz, P. and Lenz, G. and Westermann, J.
International Journal of Cancer 136 (8): 1814-1826. 15 April 2015

Myeloid-derived suppressor cells in human peripheral blood: optimized quantification in healthy donors and patients with metastatic renal cell carcinoma.
Flörcken, A. and Takvorian, A. and Singh, A. and Gerhardt, A. and Ostendorf, B.N. and Dörken, B. and Pezzutto, A. and Westermann, J.
Immunology Letters 168 (2): 260-267. December 2015

Assessment of curated phenotype mining in neuropsychiatric disorder literature.
Fontaine, J.F. and Priller, J. and Spruth, E. and Perez-Iratxeta, C. and Andrade-Navarro, M.A.
Methods 74 : 90-96. March 2015

Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors.
Garrett, L. and Zhang, J. and Zimprich, A. and Niedermeier, K.M. and Fuchs, H. and Gailus-Durner, V. and Hrabe de Angelis, M. and Vogt Weisenhorn, D. and Wurst, W. and Hoelter, S.M.
Frontiers in Behavioral Neuroscience 9 : 302. 12 November 2015

mBISON: Finding miRNA target over-representation in gene lists from ChIP-sequencing data.
Gebhardt, M.L. and Mer, A.S. and Andrade-Navarro, M.A.
BMC Research Notes 8 (1): 157. 16 April 2015

New role for the (pro)renin receptor in T cell development.
Geisberger, S. and Maschke, U. and Gebhardt, M. and Kleinewietfeld, M. and Manzel, A. and Linker, R.A. and Chidgey, A. and Dechend, R. and Nguyen, G. and Daumke, O. and Muller, D.N. and Wright, M.D. and Binger, K.J.
Blood 126 (4): 504-507. 23 July 2015

CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Ghorashian, S. and Veliça, P. and Chua, I. and McNicol, A. and Carpenter, B. and Holler, A. and Nicholson, E. and Ahmadi, M. and Zech, M. and Xue, S. and Uckert, W. and Morris, E. and Chakraverty, R. and Stauss, H.J.
Journal of Immunology 194 (3): 1080-1089. 1 February 2015

2D and 3D similarity landscape analysis identifies PARP as a novel off-target for the drug Vatalanib.
Gohlke, B.O. and Overkamp, T. and Richter, A. and Richter, A. and Daniel, P.T. and Gillissen, B. and Preissner, R.
BMC Bioinformatics 16 (1): 308. 24 September 2015

Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Grajales-Reyes, G.E. and Iwata, A. and Albring, J. and Wu, X. and Tussiwand, R. and Kc, W. and Kretzer, N.M. and Briseno, C.G. and Durai, V. and Bagadia, P. and Haldar, M. and Schoenheit, J. and Rosenbauer, F. and Murphy, T.L. and Murphy, K.M.
Nature Immunology 16 (7): 708-717. July 2015

Molecular signaling mechanisms of axon-glia communication in the peripheral nervous system.
Grigoryan, T. and Birchmeier, W.
BioEssays 37 (5): 502-513. May 2015

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S. and Eckert, C. and Arkona, C. and Radetzki, S. and Böhm, K. and Heinemann, U. and Wolber, G. and von Kries, J.P. and Birchmeier, W. and Rademann, J.
ChemMedChem 10 (5): 815-826. May 2015

A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4.
Hansen, M.T. and Forst, B. and Cremers, N. and Quagliata, L. and Ambartsumian, N. and Grum-Schwensen, B. and Klingelhoefer, J. and Abdul-Al, A. and Herrmann, P. and Osterland, M. and Stein, U. and Nielsen, G.H. and Scherer, P.E. and Lukanidin, E. and Sleeman, J.P. and Grigorian, M.
Oncogene 34 (4): 424-435. 22 January 2015

B cell localization and migration in health and disease.
Hauser, A.E. and Hoepken, U.E.
In: Molecular Biology of B Cells. UNSPECIFIED, 187-214. ISBN 978-0-12-397933-9 2015

Allogeneic stem cell transplantation for refractory acute myeloid leukemia: a single center analysis of long-term outcome.
Hemmati, P.G. and Terwey, T.H. and Na, I.K. and Jehn, C.F. and le Coutre, P. and Vuong, L.G. and Doerken, B. and Arnold, R.
European Journal of Haematology 95 (6): 498-506. December 2015

Impact of early remission by induction therapy on allogeneic stem cell transplantation for acute myeloid leukemia with an intermediate risk karyotype in first complete remission.
Hemmati, P.G. and Terwey, T.H. and Na, I.K. and le Coutre, P. and Jehn, C.F. and Vuong, L.G. and Dörken, B. and Arnold, R.
European Journal of Haematology 94 (5): 431-438. May 2015

Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F. and a Dzaye, O.D. and Hahn, A. and Yu, Y. and Scavetta, R.J. and Dittmar, G. and Kaczmarek, A.K. and Dunning, K.R. and Ricciardelli, C. and Rinnenthal, J.L. and Heppner, F.L. and Lehnardt, S. and Synowitz, M. and Wolf, S.A. and Kettenmann, H.
Neuro-Oncology 17 (2): 200-210. February 2015

Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.
Hu, Y.C. and Nicholls, P.K. and Soh, Y.Q.S. and Daniele, J.R. and Junker, J.P. and van Oudenaarden, A. and Page, D.C.
PLoS Genetics 11 (3): e1005019. 4 March 2015

JAMM: a peak finder for joint analysis of NGS replicates.
Ibrahim, M.M. and Lacadie, S.A. and Ohler, U.
Bioinformatics 31 (1): 48-55. 1 January 2015

High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.
Ilm, K. and Kemmner, W. and Osterland, M. and Burock, S. and Koch, G. and Herrmann, P. and Schlag, P.M. and Stein, U.
Molecular Cancer 14 (1): 38. 14 February 2015

Differential expression of SHP-1 in chronic myeloid leukemia.
Kaeda, J. and Neuman, D. and Bonecker, S. and Mills, K. and Oberender, C. and Amini, L. and Ringel, F. and Serra, A. and Schwarz, M. and Doerken, B. and Zalcberg, I. and Le Coutre, P.
Leukemia & Lymphoma 56 (5): 1547-1549. May 2015

Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.
Kaeda, J. and Ringel, F. and Oberender, C. and Mills, K. and Quintarelli, C. and Pane, F. and Koschmieder, S. and Slany, R. and Schwarzer, R. and Saglio, G. and Hemmati, P. and van Lessen, A. and Amini, L. and Greese, M. and Vagge, E. and Burmeister, T. and Serra, A. and Carson, A. and Schwarz, M. and Westermann, J. and Jundt, F. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 56 (7): 2105-2113. July 2015

A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.
Klinghammer, K. and Raguse, J.D. and Plath, T. and Albers, A.E. and Joehrens, K. and Zakarneh, A. and Brzezicha, B. and Wulf-Goldenberg, A. and Keilholz, U. and Hoffmann, J. and Fichtner, I.
International Journal of Cancer 136 (12): 2940-2948. 15 June 2015

TET proteins and 5-methylcytosine oxidation in hematological cancers.
Ko, M. and An, J. and Pastor, W.A. and Koralov, S.B. and Rajewsky, K. and Rao, A.
Immunological Reviews 263 (1): 6-21. January 2015

Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study.
Koelzer, V.H. and Herrmann, P. and Zlobec, I. and Karamitopoulou, E. and Lugli, A. and Stein, U.
BMC Cancer 15 (1): 160. 21 March 2015

An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex.
Kracker, S. and Di Virgilio, M. and Schwartzentruber, J. and Cuenin, C. and Forveille, M. and Deau, M.C. and McBride, K.M. and Majewski, J. and Gazumyan, A. and Seneviratne, S. and Grimbacher, B. and Kutukculer, N. and Herceg, Z. and Cavazzana, M. and Jabado, N. and Nussenzweig, M.C. and Fischer, A. and Durandy, A.
Journal of Allergy and Clinical Immunology 135 (4): 998-1007. April 2015

Deletions, inversions, duplications: engineering of structural variants using CRISPR/Cas in mice.
Kraft, K. and Geuer, S. and Will, A.J. and Chan, W.L. and Paliou, C. and Borschiwer, M. and Harabula, I. and Wittler, L. and Franke, M. and Ibrahim, D.M. and Kragesteen, B.K. and Spielmann, M. and Mundlos, S. and Lupiáñez, D.G. and Andrey, G.
Cell Reports 10 (5): 833-839. 10 February 2015

KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.
Kravtsova-Ivantsiv, Y. and Shomer, I. and Cohen-Kaplan, V. and Snijder, B. and Superti-Furga, G. and Gonen, H. and Sommer, T. and Ziv, T. and Admon, A. and Naroditsky, I. and Jbara, M. and Brik, A. and Pikarsky, E. and Kwon, Y.T. and Doweck, I. and Ciechanover, A.
Cell 161 (2): 333-347. 9 April 2015

Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: its more than NF-κB!
Kreher, S. and Cauchy, P. and Bonifer, C. and Mathas, S.
Cytokine 72 (1): 115-117. March 2015

Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9.
Kühn, R. and Chu, V.T.
Genome Biology 16 (1): 244. 10 November 2015

How cell death shapes cancer.
Labi, V. and Erlacher, M.
Cell Death & Disease 6 : e1675. 5 March 2015

Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.
Lan, L. and Holland, J.D. and Qi, J. and Grosskopf, S. and Rademann, J. and Vogel, R. and Gyoerffy, B. and Wulf-Goldenberg, A. and Birchmeier, W.
EMBO Journal 34 (11): 1493-1508. 3 June 2015

Metastasis-associated in colon cancer 1 is an independent prognostic biomarker for survival in klatskin tumor patients.
Lederer, A. and Herrmann, P. and Seehofer, D. and Dietel, M. and Pratschke, J. and Schlag, P. and Stein, U.
Hepatology 62 (3): 841-850. September 2015

Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs].
Leisegang, M. and Uckert, W.
BIOspektrum 21 (4): 402-405. June 2015

Impact of prior treatment on outcome of transformed follicular lymphoma and relapsed de novo diffuse large B cell lymphoma: a retrospective multicentre analysis.
Lerch, K. and Meyer, A.H. and Stroux, A. and Hirt, C. and Keller, U. and Viardot, A. and Marks, R. and Schreiber, S. and Pezzutto, A. and Scholz, C.W.
Annals of Hematology 94 (6): 981-988. June 2015

Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7.
Lorenz, F.K.M. and Wilde, S. and Voigt, K. and Kieback, E. and Mosetter, B. and Schendel, D.J. and Uckert, W.
PLoS ONE 10 (3): e0121633. 23 March 2015

Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions.
Lupiáñez, D.G. and Kraft, K. and Heinrich, V. and Krawitz, P. and Brancati, F. and Klopocki, E. and Horn, D. and Kayserili, H. and Opitz, J.M. and Laxova, R. and Santos-Simarro, F. and Gilbert-Dussardier, B. and Wittler, L. and Borschiwer, M. and Haas, S.A. and Osterwalder, M. and Franke, M. and Timmermann, B. and Hecht, J. and Spielmann, M. and Visel, A. and Mundlos, S.
Cell 161 (5): 1012-1025. 21 May 2015

Extensive identification and analysis of conserved small ORFs in animals.
Mackowiak, S.D. and Zauber, H. and Bielow, C. and Thiel, D. and Kutz, K. and Calviello, L. and Mastrobuoni, G. and Rajewsky, N. and Kempa, S. and Selbach, M. and Obermayer, B.
Genome Biology 16 : 179. 14 September 2015

Comprehensive identification and characterization of conserved small ORFs in animals.
Mackowiak, S.D. and Zauber, H. and Bielow, C. and Thiel, D. and Kutz, K. and Calviello, L. and Mastrobuoni, G. and Rajewsky, N. and Kempa, S. and Selbach, M. and Obermayer, B.
bioRxiv : 017772. 9 April 2015

Disassembly of Lys11- and mixed-linkage polyubiquitin conjugates provide insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.
Mansour, W. and Nakasone, M.A. and von Delbrück, M. and Yu, Z. and Krutauz, D. and Reis, N. and Kleifeld, O. and Sommer, T. and Fushman, D. and Glickman, M.H.
Journal of Biological Chemistry 290 (8): 4688-4704. 20 February 2015

Frequent induction of chromosomal aberrations in in vivo skin fibroblasts after allogeneic stem cell transplantation: hints to chromosomal instability after irradiation.
Massenkeil, G. and Zschieschang, P. and Thiel, G. and Hemmati, P.G. and Budach, V. and Doerken, B. and Pross, J. and Arnold, R.
Radiation Oncology 10 : 266. 30 December 2015

Genome-wide identification and characterisation of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing.
Mazloomian, A. and Meyer, I.M.
RNA Biology 12 (12): 1391-1401. December 2015

RAGE mediates the pro-migratory response of extracellular S100A4 in human thyroid cancer cells.
Medapati, M.R. and Dahlmann, M. and Ghavami, S. and Pathak, K.A. and Lucman, L. and Klonisch, T. and Hoang-Vu, C. and Stein, U. and Hombach-Klonisch, S.
Thyroid 25 (5): 514-527. 4 May 2015

The interplay of Hrd3 and the molecular chaperone system ensures efficient degradation of malfolded secretory proteins.
Mehnert, M. and Sommermeyer, F. and Berger, M. and Lakshmipathy, S.K. and Gauss, R. and Aebi, M. and Jarosch, E. and Sommer, T.
Molecular Biology of the Cell 26 (2): 185-194. 15 January 2015

Structure-activity relationship study of dendritic polyglycerolamines for efficient siRNA transfection.
Mehrabadi, F.S. and Hirsch, O. and Zeisig, R. and Posocco, P. and Laurini, E. and Pricl, S. and Haag, R. and Kemmner, W. and Calderon, M.
RSC Advances 5 (96): 78760-78770. 8 September 2015

Altered B-cell subsets and functional B-cell defects in selective IgM deficiency.
Mensen, A. and Krause, T. and Hanitsch, L.G. and Meisel, C. and Kleint, M.E. and Volk, H.D. and Na, I.K. and Scheibenbogen, C.
Clinical Immunology 161 (2): 96-102. December 2015

Apoptosis-susceptibility prolongs the lack of memory B cells in acute leukemic patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A. and Oh, Y. and Becker, S.C. and Hemmati, P.G. and Jehn, C. and Westermann, J. and Szyska, M. and Göldner, H. and Dörken, B. and Scheibenbogen, C. and Arnold, R. and Na, I.K.
Biology of Blood and Marrow Transplantation 21 (11): 1895-1906. November 2015

Regnase-1 and roquin regulate a common element in inflammatory mRNAs by spatiotemporally distinct mechanisms.
Mino, T. and Murakawa, Y. and Fukao, A. and Vandenbon, A. and Wessels, H.H. and Ori, D. and Uehata, T. and Tartey, S. and Akira, S. and Suzuki, Y. and Vinuesa, C.G. and Ohler, U. and Standley, D.M. and Landthaler, M. and Fujiwara, T. and Takeuchi, O.
Cell 161 (5): 1058-1073. 21 May 2015

Monocytes compensate Kupffer cell loss during bacterial infection.
Molawi, K. and Sieweke, M.H.
Immunity 42 (1): 10-12. 20 January 2015

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Momeny, M. and Saunus, J.M. and Marturana, F. and McCart Reed, A.E. and Black, D. and Sala, G. and Iacobelli, S. and Holland, J.D. and Yu, D. and Da Silva, L. and Simpson, P.T. and Khanna, K.K. and Chenevix-Trench, G. and Lakhani, S.R.
Oncotarget 6 (6): 3932-3946. 19 February 2015

Transcriptional control of tissue formation throughout root development.
Moreno-Risueno, M.A. and Sozzani, R. and Yardımcı, G.G. and Petricka, J.J. and Vernoux, T. and Blilou, I. and Alonso, J. and Winter, C.M. and Ohler, U. and Scheres, B. and Benfey, P.N.
Science 350 (6259): 426-430. 23 October 2015

The macromolecular crystallography beamlines at BESSY II of the Helmholtz-Zentrum Berlin: current status and perspectives.
Mueller, U. and Foerster, R. and Hellmig, M. and Huschmann, F.U. and Kastner, A. and Malecki, P. and Puehringer, S. and Roewer, M. and Sparta, K. and Steffien, M. and Uehlein, M. and Wilk, P. and Weiss, M.S.
European Physical Journal Plus 130 (7): 141. July 2015

Roles of MicroRNAs in B lymphocyte physiology and oncogenesis.
Muljo, S.A. and Rajewsky, K.
In: Molecular Biology of B Cells. Academic Press, 65-73. ISBN 978-0-12-397933-9 2015

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.
Murakawa, Y. and Hinz, M. and Mothes, J. and Schuetz, A. and Uhl, M. and Wyler, E. and Yasuda, T. and Mastrobuoni, G. and Friedel, C.C. and Dölken, L. and Kempa, S. and Schmidt-Supprian, M. and Blüthgen, N. and Backofen, R. and Heinemann, U. and Wolf, J. and Scheidereit, C. and Landthaler, M.
Nature Communications 6 : 7367. 14 July 2015

Emerging role of tyrosine kinases as drugable targets in cancer.
Na, I.K. and Le Coutre, P.
Biomarker Insights 10 (S3): 29-31. 10 September 2015

BCR-ABL1 acute myeloid leukemia: clonal selection of a BCR-ABL1(-) subclone as a cause of refractory disease with nilotinib treatment.
Neuendorff, N.R. and Schwarz, M. and Hemmati, P. and Tuerkmen, S. and Bommer, C. and Burmeister, T. and Doerken, B. and le Coutre, P. and Arnold, R. and Westermann, J.
Acta Haematologica 133 (2): 237-241. 2015

Gene gun Her2/neu DNA vaccination: evaluation of vaccine efficacy in a syngeneic Her2/neu mouse tumor model.
Nguyen-Hoai, T. and Pezzutto, A. and Westermann, J.
Methods in Molecular Biology 1317 : 17-37. 2015

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice.
Obenaus, M. and Leitão, C. and Leisegang, M. and Chen, X. and Gavvovidis, I. and van der Bruggen, P. and Uckert, W. and Schendel, D.J. and Blankenstein, T.
Nature Biotechnology 33 (4): 402-407. April 2015

Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Oden, F. and Marino, S.F. and Brand, J. and Scheu, S. and Kriegel, C. and Olal, D. and Takvorian, A. and Westermann, J. and Yilmaz, B. and Hinz, M. and Daumke, O. and Höpken, U.E. and Müller, G. and Lipp, M.
Molecular Oncology 9 (7): 1348-1358. August 2015

A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Opitz, R. and Mueller, M. and Reuter, C. and Barone, M. and Soicke, A. and Roske, Y. and Piotukh, K. and Huy, P. and Beerbaum, M. and Wiesner, B. and Beyermann, M. and Schmieder, P. and Freund, C. and Volkmer, R. and Oschkinat, H. and Schmalz, H.G. and Kuehne, R.
Proceedings of the National Academy of Sciences of the United States of America 112 (16): 5011-5016. 21 April 2015

The B-cell antigen receptor integrates adaptive and innate immune signals.
Otipoby, K.L. and Waisman, A. and Derudder, E. and Srinivasan, L. and Franklin, A. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 112 (39): 12145-12150. 29 September 2015

Oncoleaking: use of the pore-forming clostridium perfringens enterotoxin (CPE) for suicide gene therapy.
Pahle, J. and Aumann, J. and Kobelt, D. and Walther, W.
Methods in Molecular Biology 1317 : 69-85. 2015

Efficacy of prophylactic low-molecular weight heparin for ambulatory patients with advanced pancreatic cancer: outcomes from the CONKO-004 trial.
Pelzer, U. and Opitz, B. and Deutschinoff, G. and Stauch, M. and Reitzig, P.C. and Hahnfeld, S. and Mueller, L. and Grunewald, M. and Stieler, J.M. and Sinn, M. and Denecke, T. and Bischoff, S. and Oettle, H. and Doerken, B. and Riess, H.
Journal of Clinical Oncology 33 (18): 2028-2034. 20 June 2015

Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes.
Pfeifer, M. and Zheng, B. and Erdmann, T. and Koeppen, H. and McCord, R. and Grau, M. and Staiger, A. and Chai, A. and Sandmann, T. and Madle, H. and Doerken, B. and Chu, Y.W. and Chen, A.I. and Lebovic, D. and Salles, G.A. and Czuczman, M.S. and Palanca-Wessels, M.C. and Press, O.W. and Advani, R. and Morschhauser, F. and Cheson, B.D. and Lenz, P. and Ott, G. and Polson, A.G. and Mundt, K.E. and Lenz, G.
Leukemia 29 (7): 1578-1586. July 2015

Personalized cancer therapy considering cytochrome P450 variability.
Preissner, S. and Simmaco, M. and Gentile, G. and Preissner, R.
Advances in Pharmacology 74 (74): 113-130. 2015

Treatment of young patients with HNF1A mutations (HNF1A-MODY).
Raile, K. and Schober, E. and Konrad, K. and Thon, A. and Grulich-Henn, J. and Meissner, T. and Woelfle, J. and Scheuing, N. and Holl, R.W.
Diabetic Medicine 32 (4): 526-530. April 2015

The Herzenberg lecture: how to make a B-1 cell?
Rajewsky, K.
Annals of the New York Academy of Sciences 1362 (1): 6-7. December 2015

The DNA deamination model of somatic antibody diversification.
Rajewsky, K.
Journal of Immunology 194 (5): 2041-2042. 1 March 2015

Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation.
Rettig, I. and Koeneke, E. and Trippel, F. and Mueller, W.C. and Burhenne, J. and Kopp-Schneider, A. and Fabian, J. and Schober, A. and Fernekorn, U. and von Deimling, A. and Deubzer, H.E. and Milde, T. and Witt, O. and Oehme, I.
Cell Death & Disease 6 : e1657. 19 February 2015

Crystal structure of the dynamin tetramer.
Reubold, T.F. and Faelber, K. and Plattner, N. and Posor, Y. and Ketel, K. and Curth, U. and Schlegel, J. and Anand, R. and Manstein, D.J. and Noé, F. and Haucke, V. and Daumke, O. and Eschenburg, S.
Nature 525 (7569): 404-408. 17 September 2015

The origins of ALK translocations.
Roukos, V. and Mathas, S.
Frontiers in Bioscience 7 : 260-268. 1 June 2015

PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones.
Sander, S. and Chu, V.T. and Yasuda, T. and Franklin, A. and Graf, R. and Calado, D.P. and Li, S. and Imami, K. and Selbach, M. and Di Virgilio, M. and Bullinger, L. and Rajewsky, K.
Immunity 43 (6): 1075-1086. 15 December 2015

Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML-Study IV.
Saussele, S. and Krauss, M.P. and Hehlmann, R. and Lauseker, M. and Proetel, U. and Kalmanti, L. and Hanfstein, B. and Fabarius, A. and Kraemer, D. and Berdel, W.E. and Bentz, M. and Staib, P. and de Wit, M. and Wernli, M. and Zettl, F. and Hebart, H.F. and Hahn, M. and Heymanns, J. and Schmidt-Wolf, I. and Schmitz, N. and Eckart, M.J. and Gassmann, W. and Bartholomaeus, A. and Pezzutto, A. and Oppliger Leibundgut, E. and Heim, D. and Krause, S.W. and Burchert, A. and Hofmann, W.K. and Hasford, J. and Hochhaus, A. and Pfirrmann, M. and Müller, M.C.
Blood 126 (1): 42-49. 2 July 2015

Loss of Gadkin affects dendritic cell migration in vitro.
Schachtner, H. and Weimershaus, M. and Stache, V. and Plewa, N. and Legler, D.F. and Höpken, U.E. and Maritzen, T.
PLoS ONE 10 (12): e0143883. 1 December 2015

Flow cytometric maturity score as a novel prognostic parameter in patients with acute myeloid leukemia.
Schneider, T. and Flörcken, A. and Singh, A. and Türkmen, S. and Burmeister, T. and Anagnostopoulos, I. and Pezzutto, A. and Dörken, B. and Westermann, J.
Annals of Hematology 94 (8): 1337-1345. August 2015

Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.
Schuijers, J. and Junker, J.P. and Mokry, M. and Hatzis, P. and Koo, B.K. and Sasselli, V. and van der Flier, L.G. and Cuppen, E. and van Oudenaarden, A. and Clevers, H.
Cell Stem Cell 16 (2): 158-170. 5 February 2015

Changes in postural syntax characterize sensory modulation and natural variation of C. elegans locomotion.
Schwarz, R.F. and Branicky, R. and Grundy, L.J. and Schafer, W.R. and Brown, A.E.X.
PLoS Computational Biology 11 (8): e1004322. 21 August 2015

Changes in postural syntax characterize sensory modulation and natural variation of C. elegans locomotion.
Schwarz, R.F. and Branicky, R. and Grundy, L.J. and Schafer, W.R. and Brown, A.E.X.
bioRxiv : 017707. 8 April 2015

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.
Schwarz, R.F. and Ng, C.K.Y. and Cooke, S.L. and Newman, S. and Temple, J. and Piskorz, A.M. and Gale, D. and Sayal, K. and Murtaza, M. and Baldwin, P.J. and Rosenfeld, N. and Earl, H.M. and Sala, E. and Jimenez-Linan, M. and Parkinson, C.A. and Markowetz, F. and Brenton, J.D.
PLoS Medicine 12 (2): e1001789. 24 February 2015

Chromatin dynamics during differentiation of myeloid cells.
Schönheit, J. and Leutz, A. and Rosenbauer, F.
Journal of Molecular Biology 427 (3): 670-687. 13 February 2015

Phosphorylation of PACSIN2 by protein kinase C triggers the removal of caveolae from the plasma membrane.
Senju, Y. and Rosenbaum, E. and Shah, C. and Hamada-Nakahara, S. and Itoh, Y. and Yamamoto, K. and Hanawa-Suetsugu, K. and Daumke, O. and Suetsugu, S.
Journal of Cell Science 128 (15): 2766-2780. 1 August 2015

Molecular contacts of ribose-phosphate backbone of mRNA with human ribosome.
Sharifulin, D.E. and Grosheva, A.S. and Bartuli, Y.S. and Malygin, A.A. and Meschaninova, M.I. and Ven'yaminova, A.G. and Stahl, J. and Graifer, D.M. and Karpova, G.G.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1849 (8): 930-939. August 2015

Comparison of inter- and intraspecies variation in humans and fruit flies.
Shih, J. and Hodge, R. and Andrade-Navarro, M.A.
Genomics Data 3 : 49-54. March 2015

Waddington's Valleys and Captain Cook's Islands.
Sieweke, M.H.
Cell Stem Cell 16 (1): 7-8. 8 January 2015

A gene regulatory program for meiotic prophase in the fetal ovary.
Soh, Y.Q.S. and Junker, J.P. and Gill, M.E. and Mueller, J.L. and van Oudenaarden, A. and Page, D.C.
PLoS Genetics 11 (9): e1005531. 17 September 2015

Cell differentiation mediated by co-culture of human umbilical cord blood stem cells with murine hepatic cells.
Stecklum, M. and Wulf-Goldenberg, A. and Purfürst, B. and Siegert, A. and Keil, M. and Eckert, K. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 51 (2): 183-191. February 2015

IFN-γ regulates CD8(+) memory T cell differentiation and survival in response to weak, but not strong, TCR signals.
Stoycheva, D. and Deiser, K. and Stärck, L. and Nishanth, G. and Schlüter, D. and Uckert, W. and Schüler, T.
Journal of Immunology 194 (2): 553-559. 15 January 2015

Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke, M. and Bounab, Y. and Strempel, N. and Klockmeier, K. and Yigit, S. and Friedrich, R.P. and Chaurasia, G. and Li, S. and Hesse, F. and Riechers, S.P. and Russ, J. and Nicoletti, C. and Boeddrich, A. and Wiglenda, T. and Haenig, C. and Schnoegl, S. and Fournier, D. and Graham, R.K. and Hayden, M.R. and Sigrist, S. and Bates, G.P. and Priller, J. and Andrade-Navarro, M.A. and Futschik, M.E. and Wanker, E.E.
Genome Research 25 (5): 701-713. May 2015

VH replacement in primary immunoglobulin repertoire diversification.
Sun, A. and Novobrantseva, T.I. and Coffre, M. and Hewitt, S.L. and Jensen, K. and Skok, J.A. and Rajewsky, K. and Koralov, S.B.
Proceedings of the National Academy of Sciences of the United States of America 112 (5): E458-E466. 3 February 2015

Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983.
Tanis, E. and Julie, C. and Emile, J.F. and Mauer, M. and Nordlinger, B. and Aust, D. and Roth, A. and Lutz, M.P. and Gruenberger, T. and Wrba, F. and Sorbye, H. and Bechstein, W. and Schlag, P. and Fisseler, A. and Ruers, T.
European Journal of Cancer 51 (17): 2708-2717. November 2015

miR-184 regulates pancreatic β-cell function according to glucose metabolism.
Tattikota, S.G. and Rathjen, T. and Hausser, J. and Khedkar, A. and Kabra, U.D. and Pandey, V.K. and Sury, M.D. and Wessels, H.H. and Mollet, I.G. and Eliasson, L. and Selbach, M. and Zinzen, R.P. and Zavolan, M. and Kadener, S. and Tschöp, M. and Jastroch, M. and Friedländer, M.R. and Poy, M.N.
Journal of Biological Chemistry 290 (33): 20284-20294. 14 August 2015

How perifosine affects liposome-encapsulated drug delivery across a cell barrier.
Testen, A and Podlipec, R and Mravljak, J and Orthmann, A and Sentjurc, M and Zeisig, R and Strancar, J and Koklic, T
Therapeutic Delivery 6 (4): 423-441. April 2015

Development of an intein-mediated split-Cas9 system for gene therapy.
Truong, D.J.J. and Kühner, K. and Kühn, R. and Werfel, S. and Engelhardt, S. and Wurst, W. and Ortiz, O.
Nucleic Acids Research 43 (13): 6450-6458. 27 July 2015

Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a negative tumors.
Ueberham, E. and Glöckner, P. and Göhler, C. and Straub, B.K. and Teupser, D. and Schönig, K. and Braeuning, A. and Höhn, A.K. and Jerchow, B. and Birchmeier, W. and Gaunitz, F. and Arendt, T. and Sansom, O. and Gebhardt, R. and Ueberham, U.
Molecular Cancer Research 13 (2): 239-249. February 2015

The IL-15 cytokine system provides growth and survival signals in hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells.
Ullrich, K. and Blumenthal-Barby, F. and Lamprecht, B. and Koechert, K. and Lenze, D. and Hummel, M. and Mathas, S. and Doerken, B. and Janz, M.
Leukemia 29 (5): 1213-1218. May 2015

DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Volk, T. and Pannicke, U. and Reisli, I. and Bulashevska, A. and Ritter, J. and Björkman, A. and Schäffer, A.A. and Fliegauf, M. and Sayar, E.H. and Salzer, U. and Fisch, P. and Pfeifer, D. and Di Virgilio, M. and Cao, H. and Yang, F. and Zimmermann, K. and Keles, S. and Caliskaner, Z. and Güner, S.Ü. and Schindler, D. and Hammarström, L. and Rizzi, M. and Hummel, M. and Pan-Hammarstroem, Q. and Schwarz, K. and Grimbacher, B.
Human Molecular Genetics 24 (25): 7361-7372. 20 December 2015

Ectodysplasin/NF-κB promotes mammary cell fate via Wnt/β-catenin pathway.
Voutilainen, M. and Lindfors, P.H. and Trela, E. and Loennblad, D. and Shirokova, V. and Elo, T. and Rysti, E. and Schmidt-Ullrich, R. and Schneider, P. and Mikkola, M.L.
PLoS Genetics 11 (11): e1005676. 18 November 2015

Light-switched inhibitors of protein tyrosine phosphatase PTP1B based on phosphonocarbonyl phenylalanine as photoactive phosphotyrosine mimetic.
Wagner, S. and Schütz, A. and Rademann, J.
Bioorganic and Medicinal Chemistry 23 (12): 2839-2847. 15 June 2015

MHCII-independent CD4(+) T cells protect injured CNS neurons via IL-4.
Walsh, J.T. and Hendrix, S. and Boato, F. and Smirnov, I. and Zheng, J. and Lukens, J.R. and Gadani, S. and Hechler, D. and Gölz, G. and Rosenberger, K. and Kammertöns, T. and Vogt, J. and Vogelaar, C. and Siffrin, V. and Radjavi, A. and Fernandez-Castaneda, A. and Gaultier, A. and Gold, R. and Kanneganti, T.D. and Nitsch, R. and Zipp, F. and Kipnis, J.
Journal of Clinical Investigation 125 (2): 699-714. 2 February 2015

Chemosensitization by diverging modulation by short-term and long-term TNF-α action on ABCB1 expression and NF-κB signaling in colon cancer.
Walther, W. and Kobelt, D. and Bauer, L. and Aumann, J. and Stein, U.
International Journal of Oncology 47 (6): 2276-2285. December 2015

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A. and Grau, M. and Erdmann, T. and Merkel, O. and Sobhiafshar, U. and Anagnostopoulos, I. and Hummel, M. and Siegert, A. and Hayford, C. and Madle, H. and Wollert-Wulf, B. and Fichtner, I. and Dörken, B. and Dirnhofer, S. and Mathas, S. and Janz, M. and Emre, N.C.T. and Rosenwald, A. and Ott, G. and Lenz, P. and Tzankov, A. and Lenz, G.
Blood 125 (1): 124-132. 1 January 2015

DAZL regulates Tet1 translation in murine embryonic stem cells.
Welling, M. and Chen, H.H. and Muñoz, J. and Musheev, M.U. and Kester, L. and Junker, J.P. and Mischerikow, N. and Arbab, M. and Kuijk, E. and Silberstein, L. and Kharchenko, P.V. and Geens, M. and Niehrs, C. and van de Velde, H. and van Oudenaarden, A. and Heck, A.J. and Geijsen, N.
EMBO Reports 16 (7): 791-802. July 2015

ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration.
Zandi, S. and Nakao, S. and Chun, K.H. and Fiorina, P. and Sun, D. and Arita, R. and Zhao, M. and Kim, E. and Schueller, O. and Campbell, S. and Taher, M. and Melhorn, M.I. and Schering, A. and Gatti, F. and Tezza, S. and Xie, F. and Vergani, A. and Yoshida, S. and Ishikawa, K. and Yamaguchi, M. and Sasaki, F. and Schmidt-Ullrich, R. and Hata, Y. and Enaida, H. and Yuzawa, M. and Yokomizo, T. and Kim, Y.B. and Sweetnam, P. and Ishibashi, T. and Hafezi-Moghadam, A.
Cell Reports 10 (7): 1173-1186. 24 February 2015

Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multi-center survey.
Zeiser, R. and Burchert, A. and Lengerke, C. and Verbeek, M. and Maas-Bauer, K. and Metzelder, S.K. and Spoerl, S. and Ditschkowski, M. and Ecsedi, M. and Sockel, K. and Ayuk, F. and Ajib, S. and de Fontbrune, F.S. and Na, I.K. and Penter, L. and Holtick, U. and Wolf, D. and Schuler, E. and Meyer, E. and Apostolova, P. and Bertz, H. and Marks, R. and Lübbert, M. and Wäsch, R. and Scheid, C. and Stölzel, F. and Ordemann, R. and Bug, G. and Kobbe, G. and Negrin, R. and Brune, M. and Spyridonidis, A. and Schmitt-Gräff, A. and van der Velden, W. and Huls, G. and Mielke, S. and Grigoleit, G.U. and Kuball, J. and Flynn, R. and Ihorst, G. and Du, J. and Blazar, B.R. and Arnold, R. and Kröger, N. and Passweg, J. and Halter, J. and Socie, G. and Beelen, D. and Peschel, C. and Neubauer, A. and Finke, J. and Duyster, J. and von Bubnoff, N.
Leukemia 29 (10): 2062-2068. October 2015

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression.
Zhang, B. and Calado, D.P. and Wang, Z. and Froehler, S. and Koechert, K. and Qian, Y. and Koralov, S.B. and Schmidt-Supprian, M. and Sasaki, Y. and Unitt, C. and Rodig, S. and Chen, W. and Dalla-Favera, R. and Alt, F.W. and Pasqualucci, L. and Rajewsky, K.
Cell Reports 11 (5): 715-726. 5 May 2015

Four RNA families with functional transient structures.
Zhu, J.Y. and Meyer, I.M.
RNA Biology 12 (1): 5-20. 2015

Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Zidek, L.M. and Ackermann, T. and Hartleben, G. and Eichwald, S. and Kortman, G. and Kiehntopf, M. and Leutz, A. and Sonenberg, N. and Wang, Z.Q. and von Maltzahn, J. and Müller, C. and Calkhoven, C.F.
EMBO Reports 16 (08): 1022-1036. August 2015

Epigenetic control of myeloid cell differentiation, identity and function.
Álvarez-Errico, D. and Vento-Tormo, R. and Sieweke, M. and Ballestar, E.
Nature Reviews Immunology 15 (1): 7-17. January 2015

2014

Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system.
Amm, I. and Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1843 (1): 182-196. January 2014

IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors.
Authier, H. and Billot, K. and Derudder, E. and Bordereaux, D. and Riviere, P. and Rodrigues-Ferreira, S. and Nahmias, C. and Baud, V.
Proceedings of the National Academy of Sciences of the United States of America 111 (41): 14794-14799. 14 October 2014

STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis.
Backert, I. and Koralov, S.B. and Wirtz, S. and Kitowski, V. and Billmeier, U. and Martini, E. and Hofmann, K. and Hildner, K. and Wittkopf, N. and Brecht, K. and Waldner, M. and Rajewsky, K. and Neurath, M.F. and Becker, C. and Neufert, C.
Journal of Immunology 193 (7): 3779-3791. 1 October 2014

PRC1-mediated gene silencing in pluripotent ES cells: function and evolution.
Becker, M. and Mah, N. and Zdzieblo, D. and Li, X. and Mer, A.S. and Andrade-Navarro, M.A. and Mueller, A.M.
Epigenetics and Human Health 2015 : 141-166. 18 November 2014

Structural identification of the VPS18 β-propeller reveals a critical role in the HOPS complex stability and function.
Behrmann, H. and Lürick, A. and Kuhlee, A. and Kleine Balderhaar, H. and Bröcker, C. and Kümmel, D. and Engelbrecht-Vandré, S. and Gohlke, U. and Raunser, S. and Heinemann, U. and Ungermann, C.
Journal of Biological Chemistry 289 (48): 33503-33512. 28 November 2014

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly.
Belz, K. and Schoeneberger, H. and Wehner, S. and Weigert, A. and Boenig, H. and Klingebiel, T. and Fichtner, I. and Fulda, S.
Blood 124 (2): 240-250. 10 July 2014

CAFE: an R package for the detection of gross chromosomal abnormalities from gene expression microarray data.
Bollen, S. and Leddin, M. and Andrade-Navarro, M.A. and Mah, N.
Bioinformatics 30 (10): 1484-1485. 15 May 2014

RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer.
Bunse, M. and Bendle, G.M. and Linnemann, C. and Bies, L. and Schulz, S. and Schumacher, T.N. and Uckert, W.
Molecular Therapy 22 (11): 1983-1991. November 2014

Mouse models of human cancer.
Böck, B.C. and Stein, U. and Schmitt, C.A. and Augustin, H.G.
Cancer Research 74 (17): 4671-4675. 1 September 2014

RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.
Dahlmann, M. and Okhrimenko, A. and Marcinkowski, P. and Osterland, M. and Herrmann, P. and Smith, J. and Heizmann, C.W. and Schlag, P.M. and Stein, U.
Oncotarget 5 (10): 3220-3233. 30 May 2014

BAR domain scaffolds in dynamin-mediated membrane fission.
Daumke, O. and Roux, A. and Haucke, V.
Cell 156 (5): 882-892. 27 February 2014

Hexosamine pathway metabolites enhance protein quality control and prolong life.
Denzel, M.S. and Storm, N.J. and Gutschmidt, A. and Baddi, R. and Hinze, Y. and Jarosch, E. and Sommer, T. and Hoppe, T. and Antebi, A.
Cell 156 (6): 1167-1178. 13 March 2014

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.
Fabian, J. and Lodrini, M. and Oehme, I. and Schier, M.C. and Thole, T.M. and Hielscher, T. and Kopp-Schneider, A. and Opitz, L. and Capper, D. and von Deimling, A. and Wiegand, I. and Milde, T. and Mahlknecht, U. and Westermann, F. and Popanda, O. and Roels, F. and Hero, B. and Berthold, F. and Fischer, M. and Kulozik, A.E. and Witt, O. and Deubzer, H.E.
Cancer Research 74 (9): 2604-2616. 1 May 2014

Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets.
Farazi, T.A. and Leonhardt, C.S. and Mukherjee, N. and Mihailovic, A. and Li, S. and Max, K.E.A. and Meyer, C. and Yamaji, M. and Cekan, P. and Jacobs, N.C. and Gerstberger, S. and Bognanni, C. and Larsson, E. and Ohler, U. and Tuschl, T.
RNA 20 (7): 1090-1102. July 2014

Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma.
Fehlker, M. and Huska, M.R. and Joens, T. and Andrade-Navarro, M.A. and Kemmner, W.
BMC Cancer 14 (1): 64. 5 February 2014

The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling.
Finsen, A.V. and Ueland, T. and Sjaastad, I. and Ranheim, T. and Ahmed, M.S. and Dahl, C.P. and Askevold, E.T. and Aakhus, S. and Husberg, C. and Fiane, A.E. and Lipp, M. and Gullestad, L. and Christensen, G. and Aukrust, P. and Yndestad, A.
PLoS ONE 9 (11): e112172. 14 November 2014

Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma.
Friesen, C. and Hormann, I. and Roscher, M. and Fichtner, I. and Alt, A. and Hilger, R. and Debatin, K.M. and Miltner, E.
Cell Cycle 13 (10): 1560-1570. 15 May 2014

In vivo shRNA screens in solid tumors.
Gargiulo, G. and Serresi, M. and Cesaroni, M. and Hulsman, D. and van Lohuizen, M.
Nature Protocols 9 (12): 2880-2902. December 2014

Similarity in targets with REST points to neural and glioblastoma related miRNAs.
Gebhardt, M.L. and Reuter, S. and Mrowka, R. and Andrade-Navarro, M.A.
Nucleic Acids Research 42 (9): 5436-5446. 14 May 2014

Tissue macrophage identity and self-renewal.
Gentek, R. and Molawi, K. and Sieweke, M.H.
Immunological Reviews 262 (1): 56-73. November 2014

Alkemio: association of chemicals with biomedical topics by text and data mining.
Gijon-Correas, J.A. and Andrade-Navarro, M.A. and Fontaine, J.F.
Nucleic Acids Research 42 (W1): W422-W429. 1 July 2014

Axon guidance factor Slit2 inhibits neural invasion and metastasis in pancreatic cancer.
Goehrig, A. and Detjen, K.M. and Hilfenhaus, G. and Koerner, J. and Welzel, M. and Arsenic, R. and Schmuck, R. and Bahra, M. and Wu, J.Y. and Wiedenmann, B. and Fischer, C.
Cancer Research 74 (5): 1529-1540. 1 March 2014

Manufacture of gene modified human T cells with a memory stem/ central memory phenotype.
Gomez-Eerland, R. and Nuijen, B. and Heemskerk, B. and van Rooij, N. and van den Berg, J.H. and Beijnen, J.H. and Uckert, W. and Kvistborg, P. and Schumacher, T. and Haanen, J.B.A.G. and Jorritsma, A.
Human Gene Therapy Methods 25 (5): 277-287. October 2014

Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP.
Gray, E.J. and Petsalaki, E. and James, D.A. and Bagshaw, R.D. and Stacey, M.M. and Rocks, O. and Gingras, A.C. and Pawson, T.
Journal of Biological Chemistry 289 (51): 35397-35408. 19 December 2014

Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells.
Halvorsen, B. and Dahl, T.B. and Smedbakken, L.M. and Singh, A. and Michelsen, A.E. and Skjelland, M. and Krohg-Sørensen, K. and Russell, D. and Höpken, U.E. and Lipp, M. and Damås, J.K. and Holm, S. and Yndestad, A. and Biessen, E.A. and Aukrust, P.
Cardiovascular Research 102 (1): 148-156. 1 April 2014

Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
Heinig, K. and Gätjen, M. and Grau, M. and Stache, V. and Anagnostopoulos, I. and Gerlach, K. and Niesner, R.A. and Cseresnyes, Z. and Hauser, A.E. and Lenz, P. and Hehlgans, T. and Brink, R. and Westermann, J. and Dörken, B. and Lipp, M. and Lenz, G. and Rehm, A. and Höpken, U.E.
Cancer Discovery 4 : 1448-1465. December 2014

Cytogenetic risk grouping by the monosomal karyotype classification is superior in predicting the outcome of acute myeloid leukemia undergoing allogeneic stem cell transplantation in complete remission.
Hemmati, P.G. and Schulze-Luckow, A. and Terwey, T.H. and le Coutre, P. and Vuong, L.G. and Doerken, B. and Arnold, R.
European Journal of Haematology 92 (2): 102-110. February 2014

HEK293-based production platform for γ-retroviral (SIN-) vectors: application for safe and efficient transfer of COL7A1 cDNA.
Hennig, K. and Raasch, L. and Kolbe, C. and Weidner, S. and Leisegang, M. and Uckert, W. and Titeux, M. and Hovnanian, A. and Kuehlcke, K. and Loew, R.
Human Gene Therapy Clinical Development 25 (4): 218-228. December 2014

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J. and Kosel, F. and Qi, J. and Grossmann, K.S. and Rajewsky, K. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 111 (9): 3472-3477. 4 March 2014

The IκB kinase complex in NF-κB regulation and beyond.
Hinz, M. and Scheidereit, C.
EMBO Reports 15 (1): 46-61. 1 January 2014

Transcriptome-wide identification of protein binding sites on RNA by PAR-CLIP (photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation).
Hoell, J.I. and Hafner, M. and Landthaler, M. and Ascano, M. and Farazi, T.A. and Wardle, G. and Nusbaum, J. and Cekan, P. and Khorshid, M. and Burger, L. and Zavolan, M. and Tuschl, T.
In: Handbook of RNA Biochemistry: Second, Completely Revised and Enlarged Edition. Wiley-VCH (Germany), 877-898. ISBN 9783527327645 2014

Lymphotoxin-α keeps the gate open for T-cell infiltration in cHL.
Hoepken, U.E.
Blood 124 (19): 2897-2898. 6 November 2014

B cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.
Hojer, C. and Frankenberger, S. and Strobl, L.J. and Feicht, S. and Djermanovic, K. and Jagdhuber, F. and Hömig-Hölzel, C. and Ferch, U. and Ruland, J. and Rajewsky, K. and Zimber-Strobl, U.
Cancer Research 74 (16): 4318-4328. 15 August 2014

Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib.
Huelsmann, H.J. and Rolff, J. and Bender, C. and Jarahian, M. and Korf, U. and Herwig, R. and Froehlich, H. and Thomas, M. and Merk, J. and Fichtner, I. and Sueltmann, H. and Kuner, R.
Lung Cancer 86 (2): 151-157. November 2014

Influence of comorbidity, age and performance status on treatment efficacy and safety of cetuximab plus irinotecan in irinotecan-refractory elderly patients with metastatic colorectal cancer.
Jehn, C.F. and Böning, L. and Kröning, H. and Pezzutto, A. and Lüftner, D.
European Journal of Cancer 50 (7): 1269-1275. May 2014

NF-κB in cellular senescence and cancer treatment.
Jing, H. and Lee, S.
Molecules and Cells 37 (3): 189-195. 31 March 2014

A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.
Junker, J.P. and Peterson, K.A. and Nishi, Y. and Mao, J. and McMahon, A.P. and van Oudenaarden, A.
Developmental Cell 31 (4): 448-460. 24 November 2014

Every cell is special: genome-wide studies add a new dimension to single-cell biology.
Junker, J.P. and van Oudenaarden, A.
Cell 157 (1): 8-11. 27 March 2014

Genome-wide RNA tomography in the zebrafish embryo.
Junker, J.P. and Noël, E.S. and Guryev, V. and Peterson, K.A. and Shah, G. and Huisken, J. and McMahon, A.P. and Berezikov, E. and Bakkers, J. and van Oudenaarden, A.
Cell 159 (3): 662-675. 23 October 2014

JAK2 V617F allele burden quantified by real time quantitative polymerase chain reaction and competitive polymerase chain reaction in patients with chronic myeloproliferative neoplasia.
Kaeda, J. and Bonamino, M. and Ayres-Silva, J. and Solza, C. and Ringel, F. and Blau, O. and Daumas, A. and Oberender, C. and Doerken, B. and Le Coutre, P. and Zalcberg, I.
Leukemia & Lymphoma 55 (1): 128-135. January 2014

Long-term structured follow-up is essential after curative cancer treatment.
Keilholz, U. and Pezzutto, A. and Budach, V. and Eggert, A.
Deutsches Aerzteblatt International 111 (1-2): 1-2. 6 January 2014

A method for the generation of TCR retrogenic mice.
Kieback, E. and Hilgenberg, E. and Fillatreau, S.
Methods in Molecular Biology 1193 : 117-126. 2014

NF-κB activity is required for anagen maintenance in human hair follicles in vitro.
Kloepper, J.E. and Ernst, N. and Krieger, K. and Bodo, E. and Biro, T. and Haslam, I.S. and Schmidt-Ullrich, R. and Paus, R.
Journal of Investigative Dermatology 134 (7): 2036-2038. 11 February 2014

Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector.
Kobelt, D. and Aumann, J. and Schmidt, M. and Wittig, B. and Fichtner, I. and Behrens, D. and Lemm, M. and Freundt, G. and Schlag, P.M. and Walther, W.
Molecular Oncology 8 (3): 609-619. May 2014

R-split-CHOP chemotherapy for elderly patients with diffuse large B-cell lymphoma.
Kreher, S. and Lammer, F. and Augustin, D. and Pezzutto, A. and Baldus, C.D.
European Journal of Haematology 93 (1): 70-76. July 2014

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S. and Bouhlel, M.A. and Cauchy, P. and Lamprecht, B. and Li, S. and Grau, M. and Hummel, F. and Köchert, K. and Anagnostopoulos, I. and Jöhrens, K. and Hummel, M. and Hiscott, J. and Wenzel, S.S. and Lenz, P. and Schneider, M. and Küppers, R. and Scheidereit, C. and Giefing, M. and Siebert, R. and Rajewsky, K. and Lenz, G. and Cockerill, P.N. and Janz, M. and Dörken, B. and Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111 (42): E4513-E4522. 21 October 2014

Editing and investigating genomes with TALE and CRISPR/Cas systems: Genome engineering across species using TALENs.
Kuehn, R. and Wefers, B.
Methods 69 (1): 1. 15 August 2014

Occurrence of giant focal forms of congenital hyperinsulinism with incorrect visualization by (18)F DOPA-PET/CT scanning.
Kuehnen, P. and Matthae, R. and Arya, V. and Hauptmann, K. and Rothe, K. and Waechter, S. and Singer, M. and Mohnike, W. and Eberhard, T. and Raile, K. and Lauffer, L.M. and Iakoubov, R. and Hussain, K. and Blankenstein, O.
Clinical Endocrinology 81 (6): 847-854. December 2014

Sequence Bundles: a novel method for visualising, discovering and exploring sequence motifs.
Kultys, M. and Nicholas, L. and Schwarz, R. and Goldman, N. and King, J.
BMC Proceedings 8 (Suppl 2): S8. 28 August 2014

e-RNA: a collection of web servers for comparative RNA structure prediction and visualisation.
Lai, D. and Meyer, I.M.
Nucleic Acids Research 42 (Web Server issue): W373-W376. 1 July 2014

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.
Lancini, C. and van den Berk, P.C.M. and Vissers, J.H.A. and Gargiulo, G. and Song, J.Y. and Hulsman, D. and Serresi, M. and Tanger, E. and Blom, M. and Vens, C. and van Lohuizen, M. and Jacobs, H. and Citterio, E.
Journal of Experimental Medicine 211 (9): 1759-1777. 25 August 2014

Targeting high-grade B cell lymphoma with CD19-specific T cells.
Lehmann, F.M. and Maurberger, A. and Feicht, S. and Helm, F. and Ladinig, C. and Kieback, E. and Uckert, W. and Kammertöns, T. and Kremmer, E. and Mautner, J. and Gerbitz, A. and Bornkamm, G.W.
International Journal of Cancer 135 (5): 1153-1164. 1 September 2014

Improved transcript isoform discovery using ORF graphs.
Majoros, W.H. and Lebeck, N. and Ohler, U. and Li, S.
Bioinformatics 30 (14): 1958-1964. 15 July 2014

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane.
Mehnert, M. and Sommer, T. and Jarosch, E.
Nature Cell Biology 16 (1): 77-86. January 2014

FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.
Meier, F. and Giesert, F. and Delic, S. and Faus-Kessler, T. and Matheus, F. and Simeone, A. and Hoelter, S.M. and Kühn, R. and Vogt-Weisenhorn, D.M. and Wurst, W. and Prakash, N.
PLoS ONE 9 (7): e101124. 1 July 2014

Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT.
Mensen, A. and Jöhrens, K. and Anagnostopoulos, I. and Demski, S. and Oey, M. and Stroux, A. and Hemmati, P. and Westermann, J. and Blau, O. and Wittenbecher, F. and Movassaghi, K. and Szyska, M. and Thomas, S. and Dörken, B. and Scheibenbogen, C. and Arnold, R. and Na, I.K.
Blood 124 (6): 963-972. 7 August 2014

Comparison of different rabbit ATG preparation effects on early lymphocyte subset recovery after allogeneic HSCT and its association with EBV-mediated PTLD.
Mensen, A. and Na, I.K. and Häfer, R. and Meerbach, A. and Schlecht, M. and Pietschmann, M.L. and Gruhn, B.
Journal of Cancer Research and Clinical Oncology 140 (11): 1971-1980. November 2014

Transformation and additional malignancies are leading risk factors for an adverse course of disease in marginal zone lymphoma.
Meyer, A.H. and Stroux, A. and Lerch, K. and Eucker, J. and Eitle, J. and Hohloch, K. and Andrzejak, M. and Possinger, K. and Dörken, B. and Pezzutto, A. and Scholz, C.W.
Annals of Oncology 25 (1): 210-215. January 2014

Paired-end analysis of transcription start sites in Arabidopsis reveals plant-specific promoter signatures.
Morton, T. and Petricka, J. and Corcoran, D.L. and Li, S. and Winter, C.M. and Carda, A. and Benfey, P.N. and Ohler, U. and Megraw, M.
Plant Cell 26 (7): 2746-2760. July 2014

Global target mRNA specification and regulation by the RNA-binding protein ZFP36.
Mukherjee, N. and Jacobs, N.C. and Hafner, M. and Kennington, E.A. and Nusbaum, J.D. and Tuschl, T. and Blackshear, P.J. and Ohler, U.
Genome Biology 15 (1): R12. 8 January 2014

COUGER-co-factors associated with uniquely-bound genomic regions.
Munteanu, A. and Ohler, U. and Gordân, R.
Nucleic Acids Research 42 (Web Server issue): W461-W467. July 2014

ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics.
Norton, M. and Ng, A.C. and Baird, S. and Dumoulin, A. and Shutt, T. and Mah, N. and Andrade-Navarro, M.A. and McBride, H.M. and Screaton, R.A.
Science Signaling 7 (310): ra10. 28 January 2014

Clinical lessons to be learned from patients developing chronic myeloid leukemia while on immunosuppressive therapy after solid organ transplantation: yet another dase after orthotopic heart transplantation.
Oberender, C. and Kleeberg, L. and Nienhues, N. and Gresse, M. and Doerken, B. and Riess, H. and le Coutre, P.
Case Reports in Hematology 2014 : 890438. 16 November 2014

Second-line oxaliplatin, folinic acid, and fluorouracil versus folinic acid and fluorouracil alone for gemcitabine-refractory pancreatic cancer : outcomes from the CONKO-003 trial.
Oettle, H. and Riess, H. and Stieler, J.M. and Heil, G. and Schwaner, I. and Seraphin, J. and Goerner, M. and Moelle, M. and Greten, T.F. and Lakner, V. and Bischoff, S. and Sinn, M. and Doerken, B. and Pelzer, U.
Journal of Clinical Oncology 32 (23): 2423-2429. 10 August 2014

Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein.
Olal, D. and Dick, A. and Woods, V.L. and Liu, T. and Li, S. and Devignot, S. and Weber, F. and Saphire, E.O. and Daumke, O.
Nucleic Acids Research 42 (9): 6025-6037. 14 May 2014

Immunotherapy of B cell non-Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model.
Panjideh, H. and Mueller, G. and Koch, M. and Wilde, F. and Scheu, S. and Moldenhauer, G. and Lipp, M.
International Journal of Cancer 135 (11): 2623-2632. 1 December 2014

Intensified chemotherapy and simultaneous treatment with heparin in outpatients with pancreatic cancer - the CONKO 004 pilot trial.
Pelzer, U. and Hilbig, A. and Stieler, J.M. and Bahra, M. and Sinn, M. and Gebauer, B. and Doerken, B. and Riess, H.
BMC Cancer 14 (1): 204. 19 March 2014

Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts.
Perez, C. and Jukica, A. and Listopad, J.J. and Anders, K. and Kühl, A.A. and Loddenkemper, C. and Blankenstein, T. and Charo, J.
International Journal of Cancer 137 (2): 359-371. 15 July 2014

Simple derivation of transgene-free iPS cells by a dual recombinase approach.
Pertek, A. and Meier, F. and Irmler, M. and Beckers, J. and Skylaki, S. and Endele, M. and Wurst, W. and Prakash, N. and Kühn, R.
Molecular Biotechnology 56 (8): 697-713. August 2014

A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.
Pieper, K. and Rizzi, M. and Speletas, M. and Smulski, C.R. and Sic, H. and Kraus, H. and Salzer, U. and Fiala, G.J. and Schamel, W.W. and Lougaris, V. and Plebani, A. and Hammarstrom, L. and Recher, M. and Germenis, A.E. and Grimbacher, B. and Warnatz, K. and Rolink, A.G. and Schneider, P. and Notarangelo, L.D. and Eibel, H.
Journal of Allergy and Clinical Immunology 133 (4): 1222-1225. April 2014

Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells.
Pinto, S. and Sommermeyer, D. and Michel, C. and Wilde, S. and Schendel, D. and Uckert, W. and Blankenstein, T. and Kyewski, B.
European Journal of Immunology 44 (9): 2811-2821. September 2014

Design of a bZip transcription factor with homo/heterodimer-induced DNA-binding preference.
Pogenberg, V. and Consani Textor, L. and Vanhille, L. and Holton, S.J. and Sieweke, M.H. and Wilmanns, M.
Structure 22 (3): 466-477. 4 March 2014

Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma.
Rahal, R. and Frick, M. and Romero, R. and Korn, J.M. and Kridel, R. and Chun Chan, F. and Meissner, B. and Bhang, H.E. and Ruddy, D. and Kauffmann, A. and Farsidjani, A. and Derti, A. and Rakiec, D. and Naylor, T. and Pfister, E. and Kovats, S. and Kim, S. and Dietze, K. and Doerken, B. and Steidl, C. and Tzankov, A. and Hummel, M. and Monahan, J. and Morrissey, M.P. and Fritsch, C. and Sellers, W.R. and Cooke, V.G. and Gascoyne, R.D. and Lenz, G. and Stegmeier, F.
Nature Medicine 20 (1): 87-92. January 2014

Michael S. Neuberger 1953-2013.
Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 111 (8): 2862-2863. 25 February 2014

The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells.
Redmer, T. and Welte, Y. and Behrens, D. and Fichtner, I. and Przybilla, D. and Wruck, W. and Yaspo, M.L. and Lehrach, H. and Schaefer, R. and Regenbrecht, C.R.A.
PLoS ONE 9 (5): e92596. 5 May 2014

Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A. and Gätjen, M. and Gerlach, K. and Scholz, F. and Mensen, A. and Gloger, M. and Heinig, K. and Lamprecht, B. and Mathas, S. and Bégay, V. and Leutz, A. and Lipp, M. and Dörken, B. and Höpken, U.E.
Nature Communications 5 : 5057. 30 September 2014

TCR-engineered T cells: a model of inducible TCR expression to dissect the interrelationship between two TCRs.
Reuß, S. and Sebestyén, Z. and Heinz, N. and Loew, R. and Baum, C. and Debets, R. and Uckert, W.
European Journal of Immunology 44 (1): 265-274. January 2014

A high content screening assay for evaluation of biomaterial-mediated cell fusion processes.
Rijckaert, B. and Neffe, A.T. and Roch, T. and Gebauer, T. and Pierce, B.F. and Görs, J. and Smink, J.J. and Gossen, M. and Lendlein, A. and Leutz, A.
Macromolecular Symposia 346 (1): 91-99. December 2014

Effects of Jak2 type 1 inhibitors NVP-BSK805 and NVP-BVB808 on Jak2 mutation-positive and Bcr-Abl-positive cell lines.
Ringel, F. and Kaeda, J. and Schwarz, M. and Oberender, C. and Grille, P. and Doerken, B. and Marque, F. and Manley, P.W. and Radimerski, T. and le Coutre, P.
Acta Haematologica 132 (1): 75-86. 31 January 2014

Roquin binding to target mRNAs involves a winged helix-turn-helix motif.
Schuetz, A. and Murakawa, Y. and Rosenbaum, E. and Landthaler, M. and Heinemann, U.
Nature Communications 5 : 5701. 11 December 2014

Phylogenetic quantification of intra-tumour heterogeneity.
Schwarz, R.F. and Trinh, A. and Sipos, B. and Brenton, J.D. and Goldman, N. and Markowetz, F.
PLoS Computational Biology 10 (4): e1003535. 17 April 2014

Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model.
Schwarzer, R. and Nickel, N. and Godau, J. and Willie, B.M. and Duda, G.N. and Schwarzer, R. and Cirovic, B. and Leutz, A. and Manz, R. and Bogen, B. and Dörken, B. and Jundt, F.
Blood Cancer Journal 4 : e217. 13 June 2014

Bacteriophage P22 tailspike: structure of the complete protein and function of the interdomain linker.
Seul, A. and Müller, J.J. and Andres, D. and Stettner, E. and Heinemann, U. and Seckler, R.
Acta Crystallographica Section D 70 (Pt 5): 1336-1345. May 2014

Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C. and Hegde, B.G. and Morén, B. and Behrmann, E. and Mielke, T. and Moenke, G. and Spahn, C.M. and Lundmark, R. and Daumke, O. and Langen, R.
Structure 22 (3): 409-420. 4 March 2014

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E. and McShane, E. and Cheret, C. and Walcher, J. and Müller, T. and Wulf-Goldenberg, A. and Hoelper, S. and Garratt, A.N. and Krüger, M. and Rajewsky, K. and Meijer, D. and Birchmeier, W. and Lewin, G.R. and Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

Recessive mutations in PCBD1 cause a new type of early-onset diabetes.
Simaite, D. and Kofent, J. and Gong, M. and Rüschendorf, F. and Jia, S. and Arn, P. and Bentler, K. and Ellaway, C. and Kühnen, P. and Hoffmann, G.F. and Blau, N. and Spagnoli, F.M. and Hübner, N. and Raile, K.
Diabetes 63 (10): 3557-3564. October 2014

Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways.
Simonetti, M. and Agarwal, N. and Stösser, S. and Bali, K.K. and Karaulanov, E. and Kamble, R. and Pospisilova, B. and Kurejova, M. and Birchmeier, W. and Niehrs, C. and Heppenstall, P. and Kuner, R.
Neuron 83 (1): 104-121. 2 July 2014

Peripheral blood sCD3(-) CD4(+) T cells: a useful diagnostic tool in angioimmunoblastic T cell lymphoma.
Singh, A. and Schabath, R. and Ratei, R. and Stroux, A. and Klemke, C.D. and Nebe, T. and Flörcken, A. and van Lessen, A. and Anagnostopoulos, I. and Dörken, B. and Ludwig, W.D. and Pezzutto, A. and Westermann, J.
Hematological Oncology 32 (1): 16-21. March 2014

α-smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study.
Sinn, M. and Denkert, C. and Striefler, J.K. and Pelzer, U. and Stieler, J.M. and Bahra, M. and Lohneis, P. and Doerken, B. and Oettle, H. and Riess, H. and Sinn, B.V.
British Journal of Cancer 111 (10): 1917-1923. 11 November 2014

SPARC expression in resected pancreatic cancer patients treated with Gemcitabine: results from the CONKO-001 study.
Sinn, M. and Sinn, B.V. and Striefler, J.K. and Lindner, J.L. and Stieler, J.M. and Lohneis, P. and Bischoff, S. and Blaeker, H. and Pelzer, U. and Neuhaus, P. and Dietel, M. and Doerken, B. and Oettle, H. and Riess, H. and Denkert, C.
Annals of Oncology 25 (5): 1025-1032. May 2014

Rsp5/Nedd4 clears cells of heat-damaged proteins.
Sommer, T. and Weber, A. and Jarosch, E.
Nature Cell Biology 16 (12): 1130-1132. 1 December 2014

The ubiquitin-proteasome-system.
Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1843 (1): 1. January 2014

CellFinder: a cell data repository.
Stachelscheid, H. and Seltmann, S. and Lekschas, F. and Fontaine, J.F. and Mah, N. and Neves, M. and Andrade-Navarro, M.A. and Leser, U. and Kurtz, A.
Nucleic Acids Research 42 (1): D950-D958. 1 January 2014

Immunotherapy with TCR-redirected T cells: comparison of TCR-transduced and TCR-engineered hematopoietic stem cell-derived T cells.
Stärck, L. and Popp, K. and Pircher, H. and Uckert, W.
Journal of Immunology 192 (1): 206-213. 1 January 2014

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
Suratanee, A. and Schaefer, M.H. and Betts, M.J. and Soons, Z. and Mannsperger, H. and Harder, N. and Oswald, M. and Gipp, M. and Ramminger, E. and Marcus, G. and Männer, R. and Rohr, K. and Wanker, E. and Russell, R.B. and Andrade-Navarro, M.A. and Eils, R. and König, R.
PLoS Computational Biology 10 (9): e1003814. 25 September 2014

Generation of memory B cells inside and outside germinal centers.
Takemori, T. and Kaji, T. and Takahashi, Y. and Shimoda, M. and Rajewsky, K.
European Journal of Immunology 44 (5): 1258-1264. May 2014

Comparison of chimerism and minimal residual disease monitoring for relapse prediction after allogeneic stem cell transplantation for adult acute lymphoblastic leukemia.
Terwey, T.H. and Hemmati, P.G. and Nagy, M. and Pfeifer, H. and Goekbuget, N. and Brueggemann, M. and Le Duc, T.M. and le Coutre, P. and Doerken, B. and Arnold, R.
Biology of Blood and Marrow Transplantation 20 (10): 1522-1529. October 2014

Efficacy of CAR T-cell therapy in large tumors relies upon stromal targeting by IFNγ.
Textor, A. and Listopad, J.J. and Wührmann, L.L. and Perez, C. and Kruschinski, A. and Chmielewski, M. and Abken, H. and Blankenstein, T. and Charo, J.
Cancer Research 74 (23): 6796-6805. 1 December 2014

High prevalence of immunoglobulin light chain gene aberrations as revealed by FISH in multiple myeloma and MGUS.
Tuerkmen, S. and Binder, A. and Gerlach, A. and Niehage, S. and Melissari, M.T. and Inandiklioglu, N. and Doerken, B. and Burmeister, T.
Genes Chromosomes & Cancer 53 (8): 650-656. August 2014

B-cell-intrinsic STAT6 signaling controls germinal center formation.
Turqueti-Neves, A. and Otte, M. and da Costa, O.P. and Höpken, U.E. and Lipp, M. and Buch, T. and Voehringer, D.
European Journal of Immunology 44 (7): 2130-2138. July 2014

Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.
Vaeth, M. and Mueller, G. and Stauss, D. and Dietz, L. and Klein-Hessling, S. and Serfling, E. and Lipp, M. and Berberich, I. and Berberich-Siebelt, F.
Journal of Experimental Medicine 211 (3): 545-561. 10 March 2014

Antitumor efficacy, pharmacokinetic and biodistribution studies of the anticancer peptide CIGB-552 in mouse models.
Vallespi, M.G. and Pimentel, G. and Cabrales-Rico, A. and Garza, J. and Oliva, B. and Mendoza, O. and Gomez, Y. and Basaco, T. and Sanchez, I. and Calderon, C. and Rodriguez, J.C. and Markelova, M.R. and Fichtner, I. and Astrada, S. and Bollati-Fogolín, M. and Garay, H.E. and Reyes, O.
Journal of Peptide Science 20 (11): 850-859. November 2014

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K. and Ullrich, F. and Muench, J. and Lazarow, K. and Lutter, D. and Mah, N. and Andrade-Navarro, M.A. and von Kries, J.P. and Stauber, T. and Jentsch, T.J.
Science 344 (6184): 634-638. 9 May 2014

In vitro and in vivo investigations into the carbene copper bromide anticancer drug candidate WBC4.
Walther, W. and Fichtner, I. and Hackenberg, F. and Streciwilk, W. and Tacke, M.
Letters in Drug Design & Discovery 11 (7): 825-832. August 2014

Crystal structure of the yeast TRAPP-associated protein Tca17.
Wang, C. and Gohlke, U. and Roske, Y. and Heinemann, U.
FEBS Journal 281 (18): 4195-4206. September 2014

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. and Xie, G. and Singh, M. and Ghanbarian, A.T. and Raskó, T. and Szvetnik, A. and Cai, H. and Besser, D. and Prigione, A. and Fuchs, N.V. and Schumann, G.G. and Chen, W. and Lorincz, M.C. and Ivics, Z. and Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Generation of targeted mouse mutants by embryo microinjection of TALENs.
Wefers, B. and Ortiz, O. and Wurst, W. and Kühn, R.
Methods 69 (1): 94-101. 15 August 2014

Modes of TAL effector-mediated repression.
Werner, J. and Gossen, M.
Nucleic Acids Research 42 (21): 13061-13073. 1 December 2014

The regulatory potential of upstream open reading frames in eukaryotic gene expression.
Wethmar, K.
Wiley Interdisciplinary Reviews: RNA 5 (6): 765-768. November 2014

uORFdb - a comprehensive literature database on eukaryotic uORF biology.
Wethmar, K. and Barbosa-Silva, A. and Andrade-Navarro, M.A. and Leutz, A.
Nucleic Acids Research 42 (1): D60-D67. 1 January 2014

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.
Wikman, H. and Westphal, L. and Schmid, F. and Pollari, S. and Kropidlowski, J. and Sielaff-Frimpong, B. and Glatzel, M. and Matschke, J. and Westphal, M. and Iljin, K. and Huhtala, H. and Terracciano, L. and Kallioniemi, A. and Sauter, G. and Mueller, V. and Witzel, I. and Lamszus, K. and Kemming, D. and Pantel, K.
Oncotarget 5 (10): 3076-3087. 30 May 2014

Atomistic Monte Carlo simulation of lipid membranes.
Wuestner, D. and Sklenar, H.
International Journal of Molecular Sciences 15 (2): 1767-803. 24 January 2014

Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection.
Yardımcı, G.G. and Frank, C.L. and Crawford, G.E. and Ohler, U.
Nucleic Acids Research 42 (19): 11865-11878. 29 October 2014

Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.
Yilmaz, Z.B. and Kofahl, B. and Beaudette, P. and Baum, K. and Ipenberg, I. and Weih, F. and Wolf, J. and Dittmar, G. and Scheidereit, C.
Cell Reports 9 (5): 1756-1769. 11 December 2014

Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.
Yoshida, T. and Iwata, T. and Takai, Y. and Birchmeier, W. and Yamato, M. and Okano, T.
Genes to Cells 19 (11): 842-852. November 2014

The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis.
Zatula, N. and Wiese, M. and Bunzendahl, J. and Birchmeier, W. and Perske, C. and Bleckmann, A. and Brembeck, F.H.
Oncotarget 5 (16): 6770-6787. 30 August 2014

Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome.
Zemojtel, T. and Koehler, S. and Mackenroth, L. and Jaeger, M. and Hecht, J. and Krawitz, P. and Graul-Neumann, L. and Doelken, S. and Ehmke, N. and Spielmann, M. and Oien, N.C. and Schweiger, M.R. and Krueger, U. and Frommer, G. and Fischer, B. and Kornak, U. and Floettmann, R. and Ardeshirdavani, A. and Moreau, Y. and Lewis, S.E. and Haendel, M. and Smedley, D. and Horn, D. and Mundlos, S. and Robinson, P.N.
Science Translational Medicine 6 (252): 252ra123. 3 September 2014

Dissection of open chromatin domain formation by site specific recombination in Drosophila.
Zielke, T. and Saumweber, H.
Journal of Cell Science 127 (Pt 10): 2365-2375. 15 May 2014

Redundant human omentum fat: A leap towards regenerative medicine.
lndumathi, S. and Harikrishnan, R. and Dhanasekaran, M.
In: Regenerative Medicine. Springer (U.K.), 125-133. ISBN 978-1-4471-6541-5 2014

Subcutaneous adipose tissue-derived stem cells: advancement and applications in regenerative medicine.
lndumathi, S. and Mishra, R. and Harikrishnan, R. and Dhanasekaran, M.
In: Regenerative Medicine. Springer (U.K.), 91-112. ISBN 978-1-4471-6541-5 2014

2013

Wenn Symptome im Vordergrund stehen [When Symptoms are paramount].
Adamietz, I. A. and Schlag, P. M.
Onkologe 19 (4): 262-264. April 2013

Vom "Stiefkind" zum Paradebeispiel [From "stepchild" to classic example].
Al-Batran, S.E. and Schlag, P.M.
Onkologe 19 (5): 350. May 2013

Molecular pathways: comparing the effects of drugs and T cells to effectively target oncogenes.
Anders, K. and Blankenstein, T.
Clinical Cancer Research 19 (2): 320-326. 15 January 2013

Microarray meta-analysis defines global angiogenesis-related gene expression signatures in human carcinomas.
Anders, M. and Fehlker, M. and Wang, Q. and Wissmann, C. and Pilarsky, C. and Kemmner, W. and Hoecker, M.
Molecular Carcinogenesis 52 (1): 29-38. January 2013

A method for cell type marker discovery by high-throughput gene expression analysis of mixed cell populations.
Andrade-Navarro, M.A. and Kanji, F. and Palii, C.G. and Brand, M. and Atkins, H. and Perez-Iratxeta, C.
BMC Biotechnology 13 (1): 80. 3 October 2013

An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.
Andres, D. and Gohlke, U. and Broeker, N.K. and Schulze, S. and Rabsch, W. and Heinemann, U. and Barbirz, S. and Seckler, R.
Glycobiology 23 (4): 486-494. April 2013

Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.
Augustin, I. and Gross, J. and Baumann, D. and Korn, C. and Kerr, G. and Grigoryan, T. and Mauch, C. and Birchmeier, W. and Boutros, M.
Journal of Experimental Medicine 210 (9): 1761-1777. 26 August 2013

A chronic model of arthritis supported by a strain-specific periarticular lymph node in BALB/c mice.
Baddack, U. and Hartmann, S. and Bang, H. and Grobe, J. and Loddenkemper, C. and Lipp, M. and Mueller, G.
Nature Communications 4 : 1644. 2013

Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K. and von Delbrück, M. and Dittmar, G. and Scheffner, M. and Ziv, I. and Glickman, M.H. and Ciechanover, A. and Sommer, T.
Molecular Cell 50 (4): 528-539. 23 May 2013

Synergistic activity of bortezomib and HDACis in preclinical models of B-cell precursor acute lymphoblastic leukemia via modulation of p53, PI3K/AKT and NF-κB.
Bastian, L. and Hof, J. and Pfau, M. and Fichtner, I. and Eckert, C. and Henze, G. and Prada, J. and von Stackelberg, A. and Seeger, K. and Shalapour, S.
Clinical Cancer Research 19 (6): 1445-1457. 15 March 2013

Direct homo- and hetero-interactions of MeCP2 and MBD2.
Becker, A. and Allmann, L. and Hofstaetter, M. and Casa, V. and Weber, P. and Lehmkuhl, A. and Herce, H.D. and Cardoso, M.C.
PLoS ONE 8 (1): e53730. 15 January 2013

Modeling Wnt/β-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions.
Benary, U. and Kofahl, B. and Hecht, A. and Wolf, J.
Frontiers in Physiology 4 : 21. 25 February 2013

Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.
Brockmann, M. and Poon, E. and Berry, T. and Carstensen, A. and Deubzer, H.E. and Rycak, L. and Jamin, Y. and Thway, K. and Robinson, S.P. and Roels, F. and Witt, O. and Fischer, M. and Chesler, L. and Eilers, M.
Cancer Cell 24 (1): 75-89. 8 July 2013

Single amino acid exchange in bacteriophage HK620 tailspike protein results in thousand-fold increase of its oligosaccharide affinity.
Broeker, N.K. and Gohlke, U. and Müller, J.J. and Uetrecht, C. and Heinemann, U. and Seckler, R. and Barbirz, S.
Glycobiology 23 (1): 59-68. January 2013

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Callen, E. and Di Virgilio, M. and Kruhlak, M.J. and Nieto-Soler, M. and Wong, N. and Chen, H.T. and Faryabi, R.B. and Polato, F. and Santos, M. and Starnes, L.M. and Wesemann, D.R. and Lee, J.E. and Tubbs, A. and Sleckman, B.P. and Daniel, J.A. and Ge, K. and Alt, F.W. and Fernandez-Capetillo, O. and Nussenzweig, M.C. and Nussenzweig, A.
Cell 153 (6): 1266-1280. 6 June 2013

The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription.
Cecere, G. and Hoersch, S. and Jensen, M.B. and Dixit, S. and Grishok, A.
Molecular Cell 50 (6): 894-907. 27 June 2013

Identification of live germ-cell desquamation as a major mechanism of seasonal testis regression in mammals: a study in the Iberian mole (Talpa occidentalis).
Dadhich, R.K. and Barrionuevo, F.J. and Real, F.M. and Lupiañez, D.G. and Ortega, E. and Burgos, M. and Jiménez, R.
Biology of Reproduction 88 (4): 101. 1 April 2013

HDAC11 is a novel drug target in carcinomas.
Deubzer, H.E. and Schier, M.C. and Oehme, I. and Lodrini, M. and Haendler, B. and Sommer, A. and Witt, O.
International Journal of Cancer 132 (9): 2200-2208. 1 May 2013

Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Di Virgilio, M. and Callen, E. and Yamane, A. and Zhang, W. and Jankovic, M. and Gitlin, A.D. and Feldhahn, N. and Resch, W. and Oliveira, T.Y. and Chait, B.T. and Nussenzweig, A. and Casellas, R. and Robbiani, D.F. and Nussenzweig, M.C.
Science 339 (6120): 711-715. 8 February 2013

Loss of methylation at the IFNG promoter and CNS-1 associates with the development of functional IFN-γ memory in human CD4(+) T lymphocytes.
Dong, J. and Chang, H.D. and Ivascu, C. and Qian, Y. and Rezai, S. and Okhrimenko, A. and Cosmi, L. and Maggi, L. and Eckhardt, F. and Wu, P. and Sieper, J. and Alexander, T. and Annunziato, F. and Gossen, M. and Li, J. and Radbruch, A. and Thiel, A.
European Journal of Immunology 43 (3): 793-804. March 2013

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr, J.R. and Yu, Y. and Milanovic, M. and Beuster, G. and Zasada, C. and Däbritz, J.H.M. and Lisec, J. and Lenze, D. and Gerhardt, A. and Schleicher, K. and Kratzat, S. and Purfürst, B. and Walenta, S. and Mueller-Klieser, W. and Gräler, M. and Hummel, M. and Keller, U. and Buck, A.K. and Dörken, B. and Willmitzer, L. and Reimann, M. and Kempa, S. and Lee, S. and Schmitt, C.A.
Nature 501 (7467): 421-425. 19 September 2013

MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy.
Dössinger, G. and Bunse, M. and Bet, J. and Albrecht, J. and Paszkiewicz, P.J. and Weißbrich, B. and Schiedewitz, I. and Henkel, L. and Schiemann, M. and Neuenhahn, M. and Uckert, W. and Busch, D.H.
PLoS ONE 8 (4): e61384. 26 April 2013

Stable conditional expression and effect of C/EBPβ-LIP in adipocytes using the pSLIK system.
Esteves, C.L. and Kelly, V. and Bégay, V. and Lillico, S.G. and Leutz, A. and Seckl, J.R. and Chapman, K.
Journal of Molecular Endocrinology 51 (1): 91-98. 4 June 2013

Oligomerization of dynamin superfamily proteins in health and disease.
Faelber, K. and Gao, S. and Held, M. and Posor, Y. and Haucke, V. and Noé, F. and Daumke, O.
Progress in Molecular Biology and Translational Science 117 : 411-443. 2013

Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study.
Flörcken, A. and Kopp, J. and van Lessen, A. and Movassaghi, K. and Takvorian, A. and Jöhrens, K. and Möbs, M. and Schönemann, C. and Sawitzki, B. and Egerer, K. and Dörken, B. and Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9 (7): 1217-1227. 1 June 2013

Anti-leukemia T cells in AML: TNF-α(+) CD8(+) T cells may escape detection and possibly reflect a stage of functional impairment.
Flörcken, A. and van Lessen, A. and Terwey, T.H. and Dörken, B. and Arnold, R. and Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 9 (7): 1200-1204. 1 June 2013

T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia.
Fogli, L.K. and Sundrud, M.S. and Goel, S. and Bajwa, S. and Jensen, K. and Derudder, E. and Sun, A. and Coffre, M. and Uyttenhove, C. and Van Snick, J. and Schmidt-Supprian, M. and Rao, A. and Grunig, G. and Durbin, J. and Casola, S.S. and Rajewsky, K. and Koralov, S.B.
Journal of Immunology 191 (6): 3100-3111. 15 September 2013

Functional and genomic analyses of α-solenoid proteins.
Fournier, D. and Palidwor, G.A. and Shcherbinin, S. and Szengel, A. and Schaefer, M.H. and Perez-Iratxeta, C. and Andrade-Navarro, M.A.
PLoS ONE 8 (11): e79894. 21 November 2013

Cell death sensitization of leukemia cells by opioid receptor activation.
Friesen, C. and Roscher, M. and Hormann, I. and Fichtner, I. and Alt, A. and Hilger, R.A. and Debatin, K.M. and Miltner, E.
Oncotarget 4 (5): 677-690. 16 April 2013

Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein.
Fröhlich, C. and Grabiger, S. and Schwefel, D. and Faelber, K. and Rosenbaum, E. and Mears, J. and Rocks, O. and Daumke, O.
EMBO Journal 32 (9): 1280-1292. 2 May 2013

Rolle und Aufgaben der chirurgischen Onkologie im Rahmen molekular definierter Therapien [Role and function of surgical oncology in molecular defined therapy].
Gaedcke, J. and Schlag, P.M. and Ghadimi, M.
Onkologe 19 (10): 858-862. October 2013

Positive and negative unintended human-induced effects on Iberian mole abundance at the edge of its distribution area.
García-López de Hierro, L. and Moleón, M. and Lupiáñez, D.G. and Virgós, E. and Jiménez, R.
Mammalian Biology 78 (4): 276-282. June 2013

In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.
Gargiulo, G. and Cesaroni, M. and Serresi, M. and de Vries, N. and Hulsman, D. and Bruggeman, S.W. and Lancini, C. and van Lohuizen, M.
Cancer Cell 23 (5): 660-676. 13 May 2013

PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating graft-versus-host-disease.
Ghosh, A. and Holland, A.M. and Dogan, Y. and Yim, N. and Rao, U.K. and Young, L.F. and West, M.L. and Singer, N.V. and Lee, H. and Na, I.K. and Tsai, J.J. and Jenq, R. and Penack, O. and Hanash, A.M. and Lezcano, C. and Murphy, G.F. and Liu, C. and Sadelain, M. and Sauer, M.G. and Sant'Angelo, D. and van den Brink, M.R.M.
Cancer Research 73 (15): 4687-4696. 1 August 2013

Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode.
Gillissen, B. and Richter, A. and Richter, A. and Overkamp, T. and Essmann, F. and Hemmati, P.G. and Preissner, R. and Belka, C. and Daniel, P.T.
Cell Death & Disease 4 : e643. 23 May 2013

Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells.
Grabundzija, I. and Wang, J. and Sebe, A. and Erdei, Z. and Kajdi, R. and Devaraj, A. and Steinemann, D. and Szuhai, K. and Stein, U. and Cantz, T. and Schambach, A. and Baum, C. and Izsvák, Z. and Sarkadi, B. and Ivics, Z.
Nucleic Acids Research 41 (3): 1829-1847. 1 February 2013

Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.
Graf, R. and Munschauer, M. and Mastrobuoni, G. and Mayr, F. and Heinemann, U. and Kempa, S. and Rajewsky, N. and Landthaler, M.
RNA Biology 10 (7): 1146-1159. 1 July 2013

New medical technologies of the future.
Graschew, G. and Rakowsky, S. and Roelofs, T.A. and Schlag, P.M.
In: 2013 International Conference on Digital Technologies (DT), 29-31 May 2013, Zilina, Slovakia. 29 May 2013

Bi-PROF: bisulfite profiling of target regions using 454 GS FLX Titanium technology.
Gries, J. and Schumacher, D. and Arand, J. and Lutsik, P. and Markelova, M.R. and Fichtner, I. and Walter, J. and Sers, C. and Tierling, S.
Epigenetics 8 (7): 765-771. July 2013

Morphological analysis and differentiation of benign cystic neoplasms of the pancreas using computed tomography and magnetic resonance imaging.
Grieser, C. and Heine, G. and Stelter, L. and Steffen, I.G. and Rothe, J.H. and Walter, T.C. and Fischer, C. and Bahra, M. and Denecke, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 185 (3): 219-227. March 2013

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T. and Stein, S. and Qi, J. and Wende, H. and Garratt, A.N. and Nave, K.A. and Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

Emotional voice processing: investigating the role of genetic variation in the serotonin transporter across development.
Grossmann, T. and Vaish, A. and Franz, J. and Schroeder, R. and Stoneking, M. and Friederici, A.D.
PLoS ONE 8 (7): e68377. 8 July 2013

Bio++: efficient extensible libraries and tools for computational molecular evolution.
Gueguen, L. and Gaillard, S. and Boussau, B. and Gouy, M. and Groussin, M. and Rochette, N.C. and Bigot, T. and Fournier, D. and Pouyet, F. and Cahais, V. and Bernard, A. and Scornavacca, C. and Nabholz, B. and Haudry, A. and Dachary, L. and Galtier, N. and Belkhir, K. and Dutheil, J.Y.
Molecular Biology and Evolution 30 (8): 1745-1750. August 2013

Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis.
Hagemann, C. and Fuchs, S. and Monoranu, C.M. and Herrmann, P. and Smith, J. and Hohmann, T. and Grabiec, U. and Kessler, A.F. and Dehghani, F. and Loehr, M. and Ernestus, R.I. and Vince, G.H. and Stein, U.
Neuro-Oncology 15 (12): 1696-1709. December 2013

An individual patient-data comparison of combined modality therapy and ABVD alone for patients with limited-stage Hodgkin lymphoma.
Hay, A.E. and Klimm, B. and Chen, B.E. and Goergen, H. and Shepherd, L.E. and Fuchs, M. and Gospodarowicz, M.K. and Borchmann, P. and Connors, J.M. and Markova, J. and Crump, M. and Lohri, A. and Winter, J.N. and Doerken, B. and Pearcey, R.G. and Diehl, V. and Horning, S.J. and Eich, H.T. and Engert, A. and Meyer, R.M.
Annals of Oncology 24 (12): 3065-3069. December 2013

Vaccine-instructed intratumoral IFN-γ enables regression of autochthonous mouse prostate cancer in allogeneic T cell transplantation.
Hess Michelini, R. and Manzo, T. and Sturmheit, T. and Basso, V. and Rocchi, M. and Freschi, M. and Listopad, J.J. and Blankenstein, T. and Bellone, M. and Mondino, A.
Cancer Research 73 (15): 4641-4652. 1 August 2013

Paul Ehrlichs "magic bullets" [Paul Ehrlichs "magic bullets"].
Hochhaus, A. and Schlag, P.M. and Cordes, N. and Hoeffken, K.
Onkologe 19 (10): 806-808. October 2013

Wnt signaling in stem and cancer stem cells.
Holland, J.D. and Klaus, A. and Garratt, A.N. and Birchmeier, W.
Current Opinion in Cell Biology 25 (2): 254-264. April 2013

Combined Wnt/β-catenin, met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome.
Holland, J.D. and Györffy, B. and Vogel, R. and Eckert, K. and Valenti, G. and Fang, L. and Lohneis, P. and Elezkurtaj, S. and Ziebold, U. and Birchmeier, W.
Cell Reports 5 (5): 1214-1227. 12 December 2013

DNA microarray and miRNA analyses reinforce the classification of follicular thyroid tumors.
Jacques, C. and Guillotin, D. and Fontaine, J.F. and Franc, B. and Mirebeau-Prunier, D. and Fleury, A. and Malthiery, Y. and Savagner, F.
Journal of Clinical Endocrinology and Metabolism 98 (5): E981-E989. May 2013

Promoter identification and transcriptional regulation of the metastasis gene MACC1 in colorectal cancer.
Juneja, M. and Ilm, K. and Schlag, P.M. and Stein, U.
Molecular Oncology 7 (5): 929-943. October 2013

It's the peptide-MHC affinity, stupid.
Kammertoens, T. and Blankenstein, T.
Cancer Cell 23 (4): 429-431. 15 April 2013

Crystal structure of native and a mutant of Lampyris turkestanicus luciferase implicate in bioluminescence color shift.
Kheirabadi, M. and Sharafian, Z. and Naderi-Manesh, H. and Heinemann, U. and Gohlke, U. and Hosseinkhani, S.
Biochimica et Biophysica Acta - Proteins and Proteomics 1834 (12): 2729-2735. 6 October 2013

Peripheral artery occlusive disease (PAOD) in chronic phase chronic myeloid leukemia patients treated with nilotinib or Imatinib.
Kim, T.D. and Rea, D. and Schwarz, M. and Grille, P. and Nicolini, F.E. and Rosti, G. and Levato, L. and Giles, F.J. and Dombret, H. and Mirault, T. and Labussiere, H. and Lindhorst, R. and Haverkamp, W. and Buschmann, I. and Doerken, B. and le Coutre, P.D.
Leukemia 27 (6): 1316-1321. 5 April 2013

An RNAi-based approach to down-regulate a gene family in vivo.
Kim, J. and Badaloni, A. and Willert, T. and Zimber-Strobl, U. and Kühn, R. and Wurst, W. and Kieslinger, M.
PLoS ONE 8 (11): e80312. 12 November 2013

Target validation in mice by constitutive and conditional RNAi.
Kleinhammer, A. and Wurst, W. and Kühn, R.
Methods in Molecular Biology 986 : 307-323. 23 January 2013

Minicircle-based vectors for nonviral gene therapy: in vitro characterization and in vivo application.
Kobelt, D. and Aumann, J. and Schleef, M. and Schmeer, M. and Stein, U. and Schlag, P.M. and Walther, W.
In: Minicircle and miniplasmid DNA vectors: the future of nonviral and viral gene transfer. Wiley (Germany), 177-188. ISBN 978-3-527-32456-9 17 April 2013

Performance of high quality minicircle DNA for in vitro and in vivo gene transfer.
Kobelt, D. and Schleef, M. and Schmeer, M. and Aumann, J. and Schlag, P.M. and Walther, W.
Molecular Biotechnology 53 (1): 80-89. January 2013

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma.
Kocak, H. and Ackermann, S. and Hero, B. and Kahlert, Y. and Oberthuer, A. and Juraeva, D. and Roels, F. and Theissen, J. and Westermann, F. and Deubzer, H. and Ehemann, V. and Brors, B. and Odenthal, M. and Berthold, F. and Fischer, M.
Cell Death & Disease 4 : e586. 11 April 2013

Evaluation of combination therapy schedules of doxorubicin and an acid-sensitive albumin-binding prodrug of doxorubicin in the MIA PaCa-2 pancreatic xenograft model.
Kratz, F. and Azab, S. and Zeisig, R. and Fichtner, I. and Warnecke, A.
International Journal of Pharmaceutics 441 (1-2): 499-506. 30 January 2013

The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore.
Kravtsova-Ivantsiv, Y. and Sommer, T. and Ciechanover, A.
Angewandte Chemie International Edition 52 (1): 192-198. 2 January 2013

T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelop proteins control virus replication in mice.
Krebs, K. and Böttinger, N. and Huang, L.R. and Chmielewski, M. and Arzberger, S. and Gasteiger, G. and Jäger, C. and Schmitt, E. and Bohne, F. and Aichler, M. and Uckert, W. and Abken, H. and Heikenwalder, M. and Knolle, P. and Protzer, U.
Gastroenterology 145 (2): 456-465. August 2013

Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury.
Kusch, A. and Hoff, U. and Bubalo, G. and Zhu, Y. and Fechner, M. and Schmidt-Ullrich, R. and Marko, L. and Müller, D.N. and Schmidt-Ott, K.M. and Guergen, D. and Blum, M. and Schunck, W.H. and Dragun, D.
Acta Physiologica 208 (1): 25-40. May 2013

On the importance of cotranscriptional RNA structure formation.
Lai, D. and Proctor, J.R. and Meyer, I.M.
RNA 19 (11): 1461-1473. November 2013

Anti-metastatic treatment in colorectal cancer: targeting signaling pathways.
Lemos, C. and Sack, U. and Schmid, F. and Juneja, M. and Stein, U.
Current Pharmaceutical Design 19 (5): 841-863. February 2013

Generation of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast-embryonic stem cell fusion.
Li, L. and Blankenstein, T.
Nature Protocols 8 (8): 1567-1582. August 2013

Integrated detection of natural antisense transcripts using strand-specific RNA sequencing data.
Li, S. and Liberman, L. and Mukherjee, N. and Benfey, P. and Ohler, U.
Genome Research 23 (10): 1730-1739. October 2013

MicroRNA signature helps distinguish early from late biochemical failure in prostate cancer.
Lichner, Z. and Fendler, A. and Saleh, C. and Nasser, A.N. and Boles, D. and Al-Haddad, S. and Kupchak, P. and Dharsee, M. and Nuin, P.S. and Evans, K.R. and Jung, K. and Stephan, C. and Fleshner, N.E. and Yousef, G.M.
Clinical Chemistry 59 (11): 1595-1603. November 2013

High-throughput identification of antigen-specific TCRs by TCR gene capture.
Linnemann, C. and Heemskerk, B. and Kvistborg, P. and Kluin, R.J.C. and Bolotin, D.A. and Chen, X. and Bresser, K. and Nieuwland, M. and Schotte, R. and Michels, S. and Gomez-Eerland, R. and Jahn, L. and Hombrink, P. and Legrand, N. and Shu, C.J. and Mamedov, I.Z. and Velds, A. and Blank, C.U. and Haanen, J.B.A.G. and Turchaninova, M.A. and Kerkhoven, R.M. and Spits, H. and Hadrup, S.R. and Heemskerk, M.H.M. and Blankenstein, T. and Chudakov, D.M. and Bendle, G.M. and Schumacher, T.N.M.
Nature Medicine 19 (11): 1534-1541. November 2013

Fas expression by tumor stroma is required for cancer eradication.
Listopad, J.J. and Kammertoens, T. and Anders, K. and Silkenstedt, B. and Willimsky, G. and Schmidt, K. and Kuehl, A.A. and Loddenkemper, C. and Blankenstein, T.
Proceedings of the National Academy of Sciences of the United States of America 110 (6): 2276-2281. 5 February 2013

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
Lodrini, M. and Oehme, I. and Schroeder, C. and Milde, T. and Schier, M.C. and Kopp-Schneider, A. and Schulte, J.H. and Fischer, M. and De Preter, K. and Pattyn, F. and Castoldi, M. and Muckenthaler, M.U. and Kulozik, A.E. and Westermann, F. and Witt, O. and Deubzer, H.E.
Nucleic Acids Research 41 (12): 6018-6033. 1 July 2013

Testing of SNS-032 in a panel of human neuroblastoma cell lines with acquired resistance to a broad range of drugs.
Loeschmann, N. and Michaelis, M. and Rothweiler, F. and Zehner, R. and Cinatl, J. and Voges, Y. and Sharifi, M. and Riecken, K. and Meyer, J. and von Deimling, A. and Fichtner, I. and Ghafourian, T. and Westermann, F. and Cinatl Jr., J.
Translational Oncology 6 (6): 685-696. December 2013

Single-molecule mRNA detection and counting in mammalian tissue.
Lyubimova, A. and Itzkovitz, S. and Junker, J.P. and Fan, Z.P. and Wu, X. and van Oudenaarden, A.
Nature Protocols 8 (9): 1743-1758. September 2013

Mechanisms of Lin28-mediated miRNA and mRNA regulation : a structural and functional perspective.
Mayr, F. and Heinemann, U.
International Journal of Molecular Sciences 14 (8): 16532-16553. 9 August 2013

Utilization of TREC and KREC quantification for the monitoring of early T- and B-cell neogenesis in adult patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A. and Ochs, C. and Stroux, A. and Wittenbecher, F. and Szyska, M. and Imberti, L. and Fillatreau, S. and Uharek, L. and Arnold, R. and Dörken, B. and Thiel, A. and Scheibenbogen, C. and Na, I.K.
Journal of Translational Medicine 11 (1): 188. 14 August 2013

A novel approach for protein subcellular location prediction using amino acid exposure.
Mer, A.S. and Andrade-Navarro, M.A.
BMC Bioinformatics 14 (1): 342. 28 November 2013

p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.
Milojkovic, A. and Hemmati, P.G. and Mueer, A. and Overkamp, T. and Chumduri, C. and Jaenicke, R.U. and Gillissen, B. and Daniel, P.T.
International Journal of Cancer 133 (11): 2551-2562. 1 December 2013

Estrogen-related receptor alpha modulates lactate dehydrogenase activity in thyroid tumors.
Mirebeau-Prunier, D. and Le Pennec, S. and Jacques, C. and Fontaine, J.F. and Gueguen, N. and Boutet-Bouzamondo, N. and Donnart, A. and Malthiery, Y. and Savagner, F.
PLoS ONE 8 (3): e58683. 13 March 2013

Klinische und epidemiologische Krebsregister : Krebsregister in Deutschland – quo vadis? [Clinical and epidemiological Cancer Registers Cancer Registers in Germany - quo vadis?].
Moeslein, G. and Haier, J. and Schlag, P.M.
Onkologe 19 (12): 1022-1024. December 2013

Transcriptional control of macrophage identity, self-renewal, and function.
Molawi, K. and Sieweke, M.H.
Advances in Immunology 120 : 269-300. 2013

M-CSF instructs myeloid lineage fate in single haematopoietic stem cells.
Mossadegh-Keller, N. and Sarrazin, S. and Kandalla, P.K. and Espinosa, L. and Stanley, E.R. and Nutt, S.L. and Moore, J. and Sieweke, M.H.
Nature 497 (7448): 239-243. 9 May 2013

Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma.
Mueller, A. and Zang, C. and Chumduri, C. and Doerken, B. and Daniel, P.T. and Scholz, C.W.
International Journal of Cancer 133 (8): 1813-1824. 15 October 2013

Lymphoma outbreak in a GASH: Sal hamster colony.
Munoz, L.J. and Ludena, D. and Gedvilaite, A. and Zvirbliene, A. and Jandrig, B. and Voronkova, T. and Ulrich, R.G. and Lopez, D.E.
Archives of Virology 158 (11): 2255-2265. November 2013

Rabbit antithymocyte globulin (Thymoglobulin(R)) impairs the thymic output of both conventional and regulatory CD4(+) T cells after allogeneic hematopoietic stem cell transplantation in adult patients.
Na, I.K. and Wittenbecher, F. and Dziubianau, M. and Herholz, A. and Mensen, A. and Kunkel, D. and Blau, O. and Blau, I. and Thiel, E. and Uharek, L. and Scheibenbogen, C. and Rieger, K. and Thiel, A.
Haematologica 98 (1): 23-30. January 2013

Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: an update.
Nakamura, M. and Schneider, M.R. and Schmidt-Ullrich, R. and Paus, R.
Journal of Dermatological Science 69 (1): 6-29. January 2013

TCR-ligand k(off) rate correlates with the protective capacity of antigen-specific CD8(+) T cells for adoptive transfer.
Nauerth, M. and Weissbrich, B. and Knall, R. and Franz, T. and Dössinger, G. and Bet, J. and Paszkiewicz, P.J. and Pfeifer, L. and Bunse, M. and Uckert, W. and Holtappels, R. and Gillert-Marien, D. and Neuenhahn, M. and Krackhardt, A. and Reddehase, M.J. and Riddell, S.R. and Busch, D.H.
Science Translational Medicine 5 (192): 192ra87. 3 July 2013

Preliminary evaluation of the CellFinder literature curation pipeline for gene expression in kidney cells and anatomical parts.
Neves, M. and Damaschun, A. and Mah, N. and Lekschas, F. and Seltmann, S. and Stachelscheid, H. and Fontaine, J.F. and Kurtz, A. and Leser, U.
Database 2013 (2013): bat020. 18 April 2013

Improvement of paraneoplastic limbic encephalitis after systemic treatment with rituximab in a patient with B-cell chronic lymphocytic leukemia.
Nogai, H. and Israel-Willner, H. and Zschenderlein, R. and Pezzutto, A.
Case Reports in Hematology 2013 : 958704. 1 August 2013

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai, H. and Wenzel, S.S. and Hailfinger, S. and Grau, M. and Kaergel, E. and Seitz, V. and Wollert-Wulf, B. and Pfeifer, M. and Wolf, A. and Frick, M. and Dietze, K. and Madle, H. and Tzankov, A. and Hummel, M. and Dörken, B. and Scheidereit, C. and Janz, M. and Lenz, P. and Thome, M. and Lenz, G.
Blood 122 (13): 2242-2250. 26 September 2013

Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial.
Nordlinger, B. and Sorbye, H. and Glimelius, B. and Poston, G.J. and Schlag, P.M. and Rougier, P. and Bechstein, W.O. and Primrose, J.N. and Walpole, E.T. and Finch-Jones, M. and Jaeck, D. and Mirza, D. and Parks, R.W. and Mauer, M. and Tanis, E. and Van Cutsem, E. and Scheithauer, W. and Gruenberger, T.
Lancet Oncology 14 (12): 1208-1215. November 2013

Sequencing of NUMB transcripts in chronic myeloid leukaemia detects two single nucleotide polymorphisms.
Oberender, C. and Kaeda, J. and Pawlaczyk-Peter, B. and Daniel, P. and Arnold, R. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 54 (2): 421-422. February 2013

Histone deacetylase 10 promotes autophagy-mediated cell survival.
Oehme, I. and Linke, J.P. and Böck, B.C. and Milde, T. and Lodrini, M. and Hartenstein, B. and Wiegand, I. and Eckert, C. and Roth, W. and Kool, M. and Kaden, S. and Gröne, H.J. and Schulte, J.H. and Lindner, S. and Hamacher-Brady, A. and Brady, N.R. and Deubzer, H.E. and Witt, O.
Proceedings of the National Academy of Sciences of the United States of America 110 (28): E2592-E2601. 9 July 2013

Using cited references to improve the retrieval of related biomedical documents.
Ortuno, F.M. and Rojas, I. and Andrade-Navarro, M.A. and Fontaine, J.F.
BMC Bioinformatics 14 : 113. 27 March 2013

Value of carbohydrate antigen 19-9 in predicting response and therapy control in patients with metastatic pancreatic cancer undergoing first-line therapy.
Pelzer, U. and Hilbig, A. and Sinn, M. and Stieler, J. and Bahra, M. and Doerken, B. and Riess, H.
Frontiers in Oncology 3 : 155. June 2013

Blood group determinates incidence for pancreatic cancer in Germany.
Pelzer, U. and Klein, F. and Bahra, M. and Sinn, M. and Doerken, B. and Neuhaus, P. and Meyer, O. and Riess, H.
Frontiers in Physiology 4 : 118. 24 May 2013

Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
Petrakis, S. and Schaefer, M.H. and Wanker, E.E. and Andrade-Navarro, M.A.
BioEssays 35 (6): 503-507. June 2013

PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer, M. and Grau, M. and Lenze, D. and Wenzel, S.S. and Wolf, A. and Wollert-Wulf, B. and Dietze, K. and Nogai, H. and Storek, B. and Madle, H. and Dörken, B. and Janz, M. and Dirnhofer, S. and Lenz, P. and Hummel, M. and Tzankov, A. and Lenz, G.
Proceedings of the National Academy of Sciences of the United States of America 110 (30): 12420-12425. 23 July 2013

B-cell biology and development.
Pieper, K. and Grimbacher, B. and Eibel, H.
Journal of Allergy and Clinical Immunology 131 (4): 959-971. April 2013

The BH3-only protein Bim(L) overrides Bcl-2-mediated apoptosis resistance in melanoma cells.
Ploetz, M. and Gillissen, B. and Quast, S.A. and Berger, A. and Daniel, P.T. and Eberle, J.
Cancer Letters 335 (1): 100-108. 10 July 2013

High immune response rates and decreased frequencies of regulatory T cells in metastatic renal cell carcinoma patients after tumor cell vaccination.
Pohla, H. and Buchner, A. and Stadlbauer, B. and Frankenberger, B. and Stevanovic, S. and Walter, S. and Frank, R. and Schwachula, T. and Olek, S. and Kopp, J. and Willimsky, G. and Stief, C.G. and Hofstetter, A. and Pezzutto, A. and Blankenstein, T. and Oberneder, R. and Schendel, D.J.
Molecular Medicine 18 : 1499-1508. 8 February 2013

COFOLD: an RNA secondary structure prediction method that takes co-transcriptional folding into account.
Proctor, J.R. and Meyer, I.M.
Nucleic Acids Research 41 (9): e102. May 2013

Active suppression induced by repetitive self-epitopes protects against EAE development.
Puentes, F. and Dickhaut, K. and Hofstaetter, M. and Falk, K. and Roetzschke, O.
PLoS ONE 8 (5): e64888. 30 May 2013

A microRNA (mmu-miR-124) prevents Sox9 expression in developing mouse ovarian cells.
Real, F.M. and Sekido, R. and Lupiáñez, D.G. and Lovell-Badge, R. and Jiménez, R. and Burgos, M.
Biology of Reproduction 89 (4): 78. 1 October 2013

Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia.
Regalo, G. and Leutz, A.
EMBO Molecular Medicine 5 (8): 1154-1164. August 2013

IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis.
Rothe, M. and Quarcoo, D. and Chashchina, A.A. and Bozrova, S.V. and Qin, Z. and Nedospasov, S.A. and Blankenstein, T. and Kammertoens, T. and Drutskaya, M.S.
Cancer Medicine 2 (6): 815-825. December 2013

CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A. and Qadri, F. and Leukel, L. and Yilmaz, R. and Fontaine, J.F. and Sihn, G. and Bader, M. and Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123 (3): 1343-1347. 1 March 2013

Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.
Schaefer, M.H. and Lopes, T.J.S. and Mah, N. and Shoemaker, J.E. and Matsuoka, Y. and Fontaine, J.F. and Louis-Jeune, C. and Eisfeld, A.J. and Neumann, G. and Perez-Iratxeta, C. and Kawaoka, Y. and Kitano, H. and Andrade-Navarro, M.A.
PLoS Computational Biology 9 (1): e1002860. 3 January 2013

Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance.
Scheller, M. and Schönheit, J. and Zimmermann, K. and Leser, U. and Rosenbauer, F. and Leutz, A.
Journal of Experimental Medicine 210 (11): 2239-2256. 21 October 2013

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
Schmidt, K. and Zilio, S. and Schmollinger, J.C. and Bronte, V. and Blankenstein, T. and Willimsky, G.
Blood 121 (10): 1740-1748. 7 March 2013

Tet-Transgenic Rodents: a comprehensive, up-to date database.
Schoenig, K. and Freundlieb, S. and Gossen, M.
Transgenic Research 22 (2): 251-254. April 2013

(90)Yttrium-ibritumomab-tiuxetan as first-line treatment for follicular lymphoma: 30 months of follow-up data from an international multicenter phase II clinical trial.
Scholz, C.W. and Pinto, A. and Linkesch, W. and Lindén, O. and Viardot, A. and Keller, U. and Hess, G. and Lastoria, S. and Lerch, K. and Frigeri, F. and Arcamone, M. and Stroux, A. and Frericks, B. and Pott, C. and Pezzutto, A.
Journal of Clinical Oncology 31 (3): 308-313. 20 January 2013

Structural insights into the mechanism of GTPase activation in the GIMAP family.
Schwefel, D. and Arasu, B.S. and Marino, S.F. and Lamprecht, B. and Köchert, K. and Rosenbaum, E. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Rocks, O. and Mathas, S. and Daumke, O.
Structure 21 (4): 550-559. 2 April 2013

PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.
Schönheit, J. and Kuhl, C. and Gebhardt, M.L. and Klett, F.F. and Riemke, P. and Scheller, M. and Huang, G. and Naumann, R. and Leutz, A. and Stocking, C. and Priller, J. and Andrade-Navarro, M.A. and Rosenbauer, F.
Cell Reports 3 (5): 1617-1628. 30 May 2013

CELDA - an ontology for the comprehensive representation of cells in complex systems.
Seltmann, S. and Stachelscheid, H. and Damaschun, A. and Jansen, L. and Lekschas, F. and Fontaine, J.F. and Nguyen-Dobinsky, T.N. and Leser, U. and Kurtz, A.
BMC Bioinformatics 14 : 228. 17 July 2013

Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Shortt, J. and Martin, B.P. and Newbold, A. and Hannan, K.M. and Devlin, J.R. and Baker, A.J. and Ralli, R. and Cullinane, C. and Schmitt, C.A. and Reimann, M. and Hall, M.N. and Wall, M. and Hannan, R.D. and Pearson, R.B. and McArthur, G.A. and Johnstone, R.W.
Blood 121 (15): 2964-2974. 11 April 2013

Beyond stem cells: self-renewal of differentiated macrophages.
Sieweke, M.H. and Allen, J.E.
Science 342 (6161): 1242974. 22 November 2013

Hepatic arterial infusion with oxaliplatin and 5-FU/folinic acid for advanced biliary tract cancer: a phase II study.
Sinn, M. and Nicolaou, A. and Gebauer, B. and Podrabsky, P. and Seehofer, D. and Ricke, J. and Doerken, B. and Riess, H. and Hildebrandt, B.
Digestive Diseases and Sciences 58 (8): 2399-2405. August 2013

Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with primary liver cancer: a phase II-study (NCT00356161).
Sinn, M. and Nicolaou, A. and Ricke, J. and Podrabsky, P. and Seehofer, D. and Gebauer, B. and Pech, M. and Neuhaus, P. and Doerken, B. and Riess, H. and Hildebrandt, B.
BMC Gastroenterology 13 : 125. 9 August 2013

Does long-term survival in patients with pancreatic cancer really exist? Results from the CONKO-001 study.
Sinn, M. and Striefler, J.K. and Sinn, B.V. and Sallmon, D. and Bischoff, S. and Stieler, J.M. and Pelzer, U. and Bahra, M. and Neuhaus, P. and Doerken, B. and Denkert, C. and Riess, H. and Oettle, H.
Journal of Surgical Oncology 108 (6): 398-402. November 2013

Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes.
Smith, S.N. and Sommermeyer, D. and Piepenbrink, K.H. and Blevins, S.J. and Bernhard, H. and Uckert, W. and Baker, B.M. and Kranz, D.M.
Journal of Molecular Biology 425 (22): 4496-4507. 15 November 2013

NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability.
Sommermeyer, D. and Conrad, H. and Krönig, H. and Gelfort, H. and Bernhard, H. and Uckert, W.
International Journal of Cancer 132 (6): 1360-1367. 15 March 2013

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.
Sparmann, A. and Xie, Y. and Verhoeven, E. and Vermeulen, M. and Lancini, C. and Gargiulo, G. and Hulsman, D. and Mann, M. and Knoblich, J.A. and van Lohuizen, M.
EMBO Journal 32 (11): 1598-1612. 29 May 2013

Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Staber, P.B. and Zhang, P. and Ye, M. and Welner, R.S. and Nombela-Arrieta, C. and Bach, C. and Kerenyi, M. and Bartholdy, B.A. and Zhang, H. and Alberich-Jorda, M. and Lee, S. and Yang, H. and Ng, F. and Zhang, J. and Leddin, M. and Silberstein, L.E. and Hoefler, G. and Orkin, S.H. and Goettgens, B. and Rosenbauer, F. and Huang, G. and Tenen, D.G.
Molecular Cell 49 (5): 934-946. 7 March 2013

Teratoma formation of human embryonic stem cells in three-dimensional perfusion culture bioreactors.
Stachelscheid, H. and Wulf-Goldenberg, A. and Eckert, K. and Jensen, J. and Edsbagge, J. and Bjoerquist, P. and Rivero, M. and Strehl, R. and Jozefczuk, J. and Prigione, A. and Adjaye, J. and Urbaniak, T. and Bussmann, P. and Zeilinger, K. and Gerlach, J.C.
Journal of Tissue Engineering and Regenerative Medicine 7 (9): 729-741. September 2013

MACC1 - a novel target for solid cancers.
Stein, U.
Expert Opinion on Therapeutic Targets 17 (9): 1039-1052. September 2013

Lymphoid to myeloid cell trans-differentiation is determined by C/EBPβ structure and post-translational modifications.
Stoilova, B. and Kowenz-Leutz, E. and Scheller, M. and Leutz, A.
PLoS ONE 8 (6): e65169. 5 June 2013

Development and application of a DNA microarray-based yeast two-hybrid system.
Suter, B. and Fontaine, J.F. and Yildirimman, R. and Raskó, T. and Schaefer, M.H. and Rasche, A. and Porras, P. and Vázquez-Álvarez, B.M. and Russ, J. and Rau, K. and Foulle, R. and Zenkner, M. and Saar, K. and Herwig, R. and Andrade-Navarro, M.A. and Wanker, E.E.
Nucleic Acids Research 41 (3): 1496-507. 1 February 2013

NIH-defined graft-versus-host disease and evidence for a potent graft-versus-leukemia effect in patients with acute lymphoblastic leukemia.
Terwey, T.H. and Le Duc, T.M. and Hemmati, P.G. and le Coutre, P. and Nagy, M. and Martus, P. and Doerken, B. and Arnold, R.
Annals of Oncology 24 (5): 1363-1370. May 2013

Short tandem repeats in the inhibitory domain of the mineralocorticoid receptor: prediction of a β-solenoid structure.
Vlassi, M. and Brauns, K. and Andrade-Navarro, M.A.
BMC Structural Biology 13 (1): 17. 2 October 2013

Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis.
Voorneveld, P.W. and Stache, V. and Jacobs, R.J. and Smolders, E. and Sitters, A.I. and Liesker, A. and Korkmaz, K.S. and Lam, S.M. and De Miranda, N.F.C.C. and Morreau, H. and Kodach, L.L. and Hardwick, J.C.H.
British Journal of Cancer 109 (7): 1805-1812. 1 October 2013

The activity of titanocene T against xenografted Caki-1 tumors.
Walther, W. and Fichtner, I. and Deally, A. and Hogan, M. and Tacke, M.
Letters in Drug Design & Discovery 10 (5): 375-381. June 2013

Current status of gene therapy for cancer.
Walther, W. and Schlag, P.M.
Current Opinion in Oncology 25 (6): 659-664. November 2013

A seven-year storage report of good manufacturing practice-grade naked plasmid DNA: stability, topology, and in vitro/in vivo functional analysis.
Walther, W. and Schmeer, M. and Kobelt, D. and Baier, R. and Harder, A. and Walhorn, V. and Anselmetti, D. and Aumann, J. and Fichtner, I. and Schleef, M.
Human Gene Therapy Clinical Development 24 (4): 147-153. December 2013

Inflammation in mice ectopically expressing human PAPA syndrome-associated PSTPIP1 A230T mutant proteins.
Wang, D. and Höing, S. and Patterson, H.C. and Ahmad, U.M. and Rathinam, V.A.K. and Rajewsky, K. and Fitzgerald, K.A. and Golenbock, D.T.
Journal of Biological Chemistry 288 (7): 4594-4601. 15 February 2013

Wdr66 is a novel marker for risk stratification and involved in epithelial-mesenchymal transition of esophageal squamous cell carcinoma.
Wang, Q. and Ma, C. and Kemmner, W.
BMC Cancer 13 (1): 137. 21 March 2013

Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA.
Wefers, B. and Panda, S.K. and Ortiz, O. and Brandl, C. and Hensler, S. and Hansen, J. and Wurst, W. and Kühn, R.
Nature Protocols 8 (12): 2355-2379. December 2013

Sequential mTOR inhibitor treatment with temsirolimus in metastatic renal cell carcinoma following failure of VEGF receptor tyrosine kinase inhibitors.
Weikert, S. and Kempkensteffen, C. and Busch, J. and Johannsen, M. and Gruenwald, V. and Zimmermann, K. and Floercken, A. and Westermann, J. and Weinkauf, L. and Miller, K. and Keilholz, U.
World Journal of Urology 31 (4): 805-809. August 2013

Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours.
Wend, P. and Fang, L. and Zhu, Q. and Schipper, J.H. and Loddenkemper, C. and Kosel, F. and Brinkmann, V. and Eckert, K. and Hindersin, S. and Holland, J.D. and Lehr, S. and Kahn, M. and Ziebold, U. and Birchmeier, W.
EMBO Journal 32 (14): 1977-1989. 17 July 2013

Functional mapping of human dynamin-1-like GTPase domain based on X-ray structure analyses.
Wenger, J. and Klinglmayr, E. and Fröhlich, C. and Eibl, C. and Gimeno, A. and Hessenberger, M. and Puehringer, S. and Daumke, O. and Goettig, P.
PLoS ONE 8 (8): e71835. 19 August 2013

MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.
Wenzel, S.S. and Grau, M. and Mavis, C. and Hailfinger, S. and Wolf, A. and Madle, H. and Deeb, G. and Doerken, B. and Thome, M. and Lenz, P. and Dirnhofer, S. and Hernandez-Ilizaliturri, F.J. and Tzankov, A. and Lenz, G.
Leukemia 27 (6): 1381-1390. June 2013

Transition from an autoimmune-prone state to fatal autoimmune disease in CCR7 and RORγt double-deficient mice is dependent on gut microbiota.
Wichner, K. and Fischer, A. and Winter, S. and Tetzlaff, S. and Heimesaat, M.M. and Bereswill, S. and Rehm, A. and Lipp, M. and Höpken, U.E.
Journal of Autoimmunity 47 : 58-72. December 2013

Adoptive T-cell therapy to treat liver cancer: Is the liver microenvironment key?
Willimsky, G. and Protzer, U. and Knolle, P. and Heikenwalder, M.
Oncotarget 4 (8): 1117-1118. August 2013

Virus-induced hepatocellular carcinomas cause antigen-specific local tolerance.
Willimsky, G. and Schmidt, K. and Loddenkemper, C. and Gellermann, J. and Blankenstein, T.
Journal of Clinical Investigation 123 (3): 1032-1043. 1 March 2013

Rabbit antithymocyte globulin induces rapid expansion of effector memory CD8 T cells without accelerating acute graft versus host disease.
Wittenbecher, F. and Rieger, K. and Dziubianau, M. and Herholz, A. and Mensen, A. and Blau, I.W. and Uharek, L. and Dörken, B. and Thiel, A. and Na, I.K.
Leukemia Research Reports 2 (2): 82-85. 27 September 2013

Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice.
Yasuda, T. and Wirtz, T. and Zhang, B. and Wunderlich, T. and Schmidt-Supprian, M. and Sommermann, T. and Rajewsky, K.
Cold Spring Harbor Symposia on Quantitative Biology 78 : 259-263. 15 November 2013

Concurrent inhibition of PI3-Kinase and mTOR induces cell death in diffuse large B cell lymphomas, a mechanism involving down regulation of Mcl-1.
Zang, C. and Eucker, J. and Liu, H. and Mueller, A. and Possinger, K. and Scholz, C.W.
Cancer Letters 339 (2): 288-297. 10 October 2013

Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery.
Zhang, G. and Hoersch, S. and Amsterdam, A. and Whittaker, C.A. and Beert, E. and Catchen, J.M. and Farrington, S. and Postlethwait, J.H. and Legius, E. and Hopkins, N. and Lees, J.A.
PLoS Genetics 9 (8): e1003734. August 2013

Fibroblast-specific protein 1/S100A4-positive cells prevent carcinoma through collagen production and encapsulation of carcinogens.
Zhang, J and Chen, L and Liu, X and Kammertoens, T. and Blankenstein, T. and Qin, Z.
Cancer Research 73 (9): 2770-2781. 1 May 2013

Transient RNA structure features are evolutionarily conserved and can be computationally predicted.
Zhu, J.Y.A. and Steif, A. and Proctor, J.R. and Meyer, I.M.
Nucleic Acids Research 41 (12): 6273-6285. 8 July 2013

SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations.
von Eichborn, J. and Dunkel, M. and Gohlke, B.O. and Preissner, S.C. and Hoffmann, M.F. and Bauer, J.M.J. and Armstrong, J.D. and Schaefer, M.H. and Andrade-Navarro, M.A. and Le Novere, N. and Croning, M.D.R. and Grant, S.G.N. and van Nierop, P. and Smit, A.B. and Preissner, R.
Nucleic Acids Research 41 (D1): D834-D840. 1 January 2013

2012

Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice.
Abolhassani, M. and Guais, A. and Sanders, E. and Campion, F. and Fichtner, I. and Bonte, J. and Baronzio, G. and Fiorentini, G. and Israel, M. and Schwartz, L.
Investigational New Drugs 30 (4): 1331-1342. August 2012

Comparative evaluation of the biological properties of reducible and acid-sensitive folate prodrugs of a highly potent doxorubicin derivative.
Abu Ajaj, K. and El-Abadla, N. and Welker, P. and Azab, S. and Zeisig, R. and Fichtner, I. and Kratz, F.
European Journal of Cancer 48 (13): 2054-2065. September 2012

Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.
Anders, K. and Buschow, C. and Charo, J. and Blankenstein, T.
Transgenic Research 21 (5): 1099-1107. October 2012

Mining the literature: new methods to exploit keyword profiles.
Andrade-Navarro, M.A.
Genome Medicine 4 (10): 81. 30 October 2012

Peer2ref: a peer-reviewer finding web tool that uses author disambiguation.
Andrade-Navarro, M.A. and Palidwor, G.A. and Perez-Iratxeta, C.
BioData Mining 5 (1): 14. 7 September 2012

Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system.
Andresen, D. and Roske, Y. and Doering, C. and Heinemann, U. and Seckler, R. and Barbirz, S.
Molecular Microbiology 83 (6): 1244-1253. March 2012

Stem cell biology-from basic research to regenerative medicine.
Besser, D.
Journal of Molecular Medicine 90 (7): 731-733. July 2012

Replicative aging and differentiation potential of human adipose tissue-derived mesenchymal stromal cells expanded in pooled human or fetal bovine serum.
Bieback, K. and Hecker, A. and Schlechter, T. and Hofmann, I. and Brousos, N. and Redmer, T. and Besser, D. and Klueter, H. and Mueller, A.M. and Becker, M.
Cytotherapy 14 (5): 570-583. May 2012

Mesenchymal stromal cells (MSCs): science and f(r)iction.
Bieback, K. and Wuchter, P. and Besser, D. and Franke, W. and Becker, M. and Ott, M. and Pacher, M. and Ma, N. and Stamm, C. and Klueter, H. and Mueller, A. and Ho, A.D.
Journal of Molecular Medicine 90 (7): 773-782. July 2012

The role of Irf6 in tooth epithelial invagination.
Blackburn, J. and Ohazama, A. and Kawasaki, K. and Otsuka-Tanaka, Y. and Liu, B. and Honda, K. and Rountree, R.B. and Hu, Y. and Kawasaki, M. and Birchmeier, W. and Schmidt-Ullrich, R. and Kinoshita, A. and Schutte, B.C. and Hammond, N.L. and Dixon, M.J. and Sharpe, P.T.
Developmental Biology 365 (1): 61-70. 1 May 2012

Spontaneous and therapy-induced T cell responses to cancer.
Blankenstein, T.
Arzneimittelforschung 62 (1): S9. November 2012

The determinants of tumour immunogenicity.
Blankenstein, T. and Coulie, P.G. and Gilboa, E. and Jaffee, E.M.
Nature Reviews Cancer 12 (4): 307-313. April 2012

A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand, J. and Smith, E.S.J. and Schwefel, D. and Lapatsina, L. and Poole, K. and Omerbasic, D. and Kozlenkov, A. and Behlke, J. and Lewin, G.R. and Daumke, O.
EMBO Journal 31 (17): 3635-3646. 29 August 2012

High-resolution experimental and computational profiling of tissue-specific known and novel miRNAs in Arabidopsis.
Breakfield, N.W. and Corcoran, D.L. and Petricka, J.J. and Shen, J. and Sae-Seaw, J. and Rubio-Somoza, I. and Weigel, D. and Ohler, U. and Benfey, P.N.
Genome Research 22 (1): 163-176. January 2012

Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates.
Briesemeister, D. and Friese, C. and Isern, C.C. and Dietz, E. and Blankenstein, T. and Thoene-Reineke, C. and Kammertoens, T.
Cytokine 60 (3): 626-633. December 2012

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Bywater, M.J. and Poortinga, G. and Sanij, E. and Hein, N. and Peck, A. and Cullinane, C. and Wall, M. and Cluse, L. and Drygin, D. and Anderes, K. and Huser, N. and Proffitt, C. and Bliesath, J. and Haddach, M. and Schwaebe, M.K. and Ryckman, D.M. and Rice, W.G. and Schmitt, C. and Lowe, S.W. and Johnstone, R.W. and Pearson, R.B. and McArthur, G.A. and Hannan, R.D.
Cancer Cell 22 (1): 51-65. 10 July 2012

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P. and Sasaki, Y. and Godinho, S.A. and Pellerin, A. and Koechert, K. and Sleckman, B.P. and de Alboran, I.M. and Janz, M. and Rodig, S. and Rajewsky, K.
Nature Immunology 13 (11): 1092-1100. November 2012

Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.
Cerrone, M. and Noorman, M. and Lin, X. and Chkourko, H. and Liang, F.X. and van der Nagel, R. and Hund, T. and Birchmeier, W. and Mohler, P. and van Veen, T.A. and van Rijen, H.V. and Delmar, M.
Cardiovascular Research 95 (4): 460-468. 1 September 2012

Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP.
Courtial, N. and Smink, J.J. and Kuvardina, O.N. and Leutz, A. and Goethert, J.R. and Lausen, J.
FASEB Journal 26 (2): 523-532. February 2012

Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.
Dahlmann, M. and Sack, U. and Herrmann, P. and Lemm, M. and Fichtner, I. and Schlag, P.M. and Stein, U.
Oncotarget 3 (8): 783-797. 7 August 2012

Genome-wide search for miRNA-target interactions in Arabidopsis thaliana with an integrated approach.
Ding, J. and Li, D. and Ohler, U. and Guan, J. and Zhou, S.
BMC Genomics 13 (Suppl 3): S3. 11 June 2012

Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.
Engert, A. and Haverkamp, H. and Kobe, C. and Markova, J. and Renner, C. and Ho, A. and Zijlstra, J. and Kral, Z. and Fuchs, M. and Hallek, M. and Kanz, L. and Doehner, H. and Doerken, B. and Engel, N. and Topp, M. and Klutmann, S. and Amthauer, H. and Bockisch, A. and Kluge, R. and Kratochwil, C. and Schober, O. and Greil, R. and Andreesen, R. and Kneba, M. and Pfreundschuh, M. and Stein, H. and Eich, H.T. and Mueller, R.P. and Dietlein, M. and Borchmann, P. and Diehl, V.
Lancet 379 (9828): 1791-1799. 12 May 2012

Regulation of adipocyte 11beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) by CCAAT/enhancer-binding protein (C/EBP) beta isoforms, LIP and LAP.
Esteves, C.L. and Kelly, V. and Begay, V. and Man, T.Y. and Morton, N.M. and Leutz, A. and Seckl, J.R. and Chapman, K.E.
PLoS ONE 7 (5): e37953. 25 May 2012

Praeklinische Validierung fuer das US-gestuetzte Navigationssystem Liver Track.
Eulenstein, S. and Jentsch, M. and Schlag, P.M.
In: Annual Meeting on CURAC (Computer- und Roboterassistierte Chirurgie), 15 Nov 2012, Duesseldorf. 2012

Structural insights into dynamin-mediated membrane fission.
Faelber, K. and Held, M. and Gao, S. and Posor, Y. and Haucke, V. and Noe, F. and Daumke, O.
Structure 20 (10): 1621-1628. 10 October 2012

Kommunikationstechnologie, Telematik und Robotik : Spagat zwischen Vision und Realitaet [Communication technology, telematics and robotics : balance between vision and reality].
Feussner, H. and Schlag, P.M.
Onkologe 18 (5): 386-388. May 2012

In vitro and in vivo investigations into the carbene silver acetate anticancer drug candidate SBC1.
Fichtner, I. and Cinatl, J. and Michaelis, M. and Sanders, L.C. and Hilger, R. and Kennedy, B.N. and Reynolds, A.L. and Hackenberg, F. and Lally, G. and Quinn, S.J. and McRae, I. and Tacke, M.
Letters in Drug Design & Discovery 9 (9): 815-822. November 2012

The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Finley, D. and Ulrich, H.D. and Sommer, T. and Kaiser, P.
Genetics 192 (2): 319-360. 1 October 2012

Sorafenib, but not sunitinib, induces regulatory T cells in the peripheral blood of patients with metastatic renal cell carcinoma.
Floercken, A. and Takvorian, A. and Van Lessen, A. and Singh, A. and Hopfenmueller, W. and Doerken, B. and Pezzutto, A. and Westermann, J.
Anti-Cancer Drugs 23 (3): 298-302. March 2012

Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D. and Luft, F.C. and Bader, M. and Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90 (5): 495-508. May 2012

New insights into the biology of molecular subtypes of diffuse large B-cell lymphoma and Burkitt lymphoma.
Frick, M. and Doerken, B. and Lenz, G.
Best Practice and Research Clinical Haematology 25 (1): 3-12. March 2012

Natural course of untreated microalbuminuria in children and adolescents with type 1 diabetes and the importance of diabetes duration and immigrant status: longitudinal analysis from the prospective nationwide German and Austrian diabetes survey DPV.
Galler, A. and Haberland, H. and Naeke, A. and Hofer, S. and Holder, M. and Raile, K. and Holl, R.W.
European Journal of Endocrinology 166 (3): 493-501. March 2012

Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer.
Galling, N. and Kobelt, D. and Aumann, J. and Schmidt, M. and Wittig, B. and Schlag, P.M. and Walther, W.
Human Gene Therapy Part B Methods 23 (4): 264-270. August 2012

A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells.
Gavvovidis, I. and Rost, I. and Trimborn, M. and Kaiser, F.J. and Purps, J. and Wiek, C. and Hanenberg, H. and Neitzel, H. and Schindler, D.
PLoS ONE 7 (8): e40387. 30 August 2012

Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.
Gerbitz, A. and Sukumar, M. and Helm, F. and Wilke, A. and Friese, C. and Fahrenwaldt, C. and Lehmann, F.M. and Loddenkemper, C. and Kammertoens, T. and Mautner, J. and Schmitt, C.A. and Blankenstein, T. and Bornkamm, G.W.
PLoS ONE 7 (3): e34552. 30 March 2012

Targeting MET in cancer: rationale and progress.
Gherardi, E. and Birchmeier, W. and Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells.
Gregersen, L.H. and Jacobsen, A. and Frankel, L.B. and Wen, J. and Krogh, A. and Lund, A.H.
BMC Cancer 12 : 232. 12 June 2012

Interdisziplinaere Tumorkonferenzen : regionale und ueberregionale telemedizinische und teleradiologische Anbindung von Tumorzentren [Interdisciplinary tumor boards : regional and supraregional telemedical and teleradiological links to tumor boards].
Guettler, F.V. and Rakowsky, S. and Nagel, S.N. and Teichgraeber, U. and Schlag, P.M.
Onkologe 18 (5): 389-397. May 2012

Finding the will and the way of ERAD substrate retrotranslocation.
Hampton, R.Y. and Sommer, T.
Current Opinion in Cell Biology 24 (4): 460-466. August 2012

Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
Hanna, J. and Schütz, A. and Zimmermann, F. and Behlke, J. and Sommer, T. and Heinemann, U.
Journal of Biological Chemistry 287 (11): 8633-8640. 9 March 2012

A role for GPx3 in activity of normal and leukemia stem cells.
Herault, O. and Hope, K.J. and Deneault, E. and Mayotte, N. and Chagraoui, J. and Wilhelm, B.T. and Cellot, S. and Sauvageau, M. and Andrade-Navarro, M.A. and Hebert, J. and Sauvageau, G.
Journal of Experimental Medicine 209 (5): 895-901. 7 May 2012

It takes two to tango: IκBs, the multifunctional partners of NF-κB.
Hinz, M. and Coel Arslan, S. and Scheidereit, C.
Immunological Reviews 246 (1): 59-76. March 2012

Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs.
Hoepken, U.E. and Rehm, A.
Journal of Molecular Medicine 90 (11): 1237-1245. November 2012

A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.
Hofgaard, P.O. and Jodal, H.C. and Bommert, K. and Huard, B. and Caers, J. and Carlsen, H. and Schwarzer, R. and Schuenemann, N. and Jundt, F. and Lindeberg, M.M. and Bogen, B.
PLoS ONE 7 (12): e51892. 20 December 2012

Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.
Horatscheck, A. and Wagner, S. and Ortwein, J. and Kim, B.G. and Lisurek, M. and Beligny, S. and Schuetz, A. and Rademann, J.
Angewandte Chemie International Edition 51 (37): 9441-9447. 10 September 2012

CCR7 with S1P(1) signaling through AP-1 for migration of Foxp3(+) regulatory T-cells controls autoimmune exocrinopathy.
Ishimaru, N. and Yamada, A. and Nitta, T. and Arakaki, R. and Lipp, M. and Takahama, Y. and Hayashi, Y.
American Journal of Pathology 180 (1): 199-208. January 2012

Influence of age, performance status, cancer activity, and IL-6 on anxiety and depression in patients with metastatic breast cancer.
Jehn, C.F. and Flath, B. and Strux, A. and Krebs, M. and Possinger, K. and Pezzutto, A. and Lueftner, D.
Breast Cancer Research and Treatment 136 (3): 789-794. December 2012

When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 45 (4): 437-438. 24 February 2012

Reduced tumor-antigen density leads to PD-1/PD-L1 mediated impairment of partially exhausted CD8(+) T cells.
Kaiser, A.D. and Schuster, K. and Gadiot, J. and Borkner, L. and Daebritz, H. and Schmitt, C. and Andreesen, R. and Blank, C.
European Journal of Immunology 42 (3): 662-671. March 2012

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
Kaji, T. and Ishige, A. and Hikida, M. and Taka, J. and Hijikata, A. and Kubo, M. and Nagashima, T. and Takahashi, Y. and Kurosaki, T. and Okada, M. and Ohara, O. and Rajewsky, K. and Takemori, T.
Journal of Experimental Medicine 209 (11): 2079-2097. 22 October 2012

B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin).
Kammertoens, T. and Qin, Z. and Briesemeister, D. and Bendelac, A. and Blankenstein, T.
International Journal of Cancer 131 (7): 1499-1508. 1 October 2012

Antibodies to the alpha(1)-adrenergic receptor cause vascular impairments in rat brain as demonstrated by magnetic resonance angiography.
Karczewski, P. and Pohlmann, A. and Wagenhaus, B. and Wisbrun, N. and Hempel, P. and Lemke, B. and Kunze, R. and Niendorf, T. and Bimmler, M.
PLoS ONE 7 (7): e41602. 30 July 2012

The Drosophila translational control element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes.
Katzenberger, R.J. and Rach, E.A. and Anderson, A.K. and Ohler, U. and Wassarman, D.A.
PLoS ONE 7 (9): e45009. 11 September 2012

The role of CCR7 in allergic airway inflammation induced by house dust mite exposure.
Kawakami, M. and Narumoto, O. and Matsuo, Y. and Horiguchi, K. and Horiguchi, S. and Yamashita, N. and Sakaguchi, M. and Lipp, M. and Nagase, T. and Yamashita, N.
Cellular Immunology 275 (1-2): 24-32. January 2012

Transcriptional expression profile of cultured human embryonic stem cells in vitro and in vivo.
Keil, M. and Siegert, A. and Eckert, K. and Gerlach, J. and Haider, W. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 48 (3): 165-174. March 2012

Loss of UDP-N-acetylglucosamine 2-epimerase/ N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells.
Kemmner, W. and Kessel, P. and Sanchez-Ruderisch, H. and Moeller, H. and Hinderlich, S. and Schlag, P.M. and Detjen, K.
FASEB Journal 26 (2): 938-946. February 2012

Clinical cardiac safety profile of nilotinib.
Kim, T.D. and le Coutre, P. and Schwarz, M. and Grille, P. and Levitin, M. and Fateh-Moghadam, S. and Giles, F.J. and Doerken, B. and Haverkamp, W. and Koehncke, C.
Haematologica 97 (6): 883-889. June 2012

Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Kirchner, F. and Schuetz, A. and Boldt, L.H. and Martens, K. and Dittmar, G. and Haverkamp, W. and Thierfelder, L. and Heinemann, U. and Gerull, B.
Circulation Cardiovascular Genetics 5 (4): 400-411. 1 August 2012

Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Klaus, A. and Mueller, M. and Schulz, H. and Saga, Y. and Martin, J.F. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 109 (27): 10921-10926. 3 July 2012

Combination therapy with the albumin-binding prodrug of doxorubicin (INNO-206) and doxorubicin achieves complete remissions and improves tolerability in an ovarian A2780 xenograft model.
Kratz, F. and Fichtner, I. and Graeser, R.
Investigational New Drugs 30 (4): 1743-1749. August 2012

XDSAPP: a graphical user interface for the convenient processing of diffraction data using XDS.
Krug, M. and Weiss, M.S. and Heinemann, U. and Mueller, U.
Journal of Applied Crystallography 45 (3): 568-572. June 2012

Computational approaches to discovering noncoding RNA.
Krzyzanowski, P.M. and Muro, E.M. and Andrade-Navarro, M.A.
Wiley Interdisciplinary Reviews: RNA 3 (4): 567-579. July 2012

Long-term lanreotide treatment in six patients with congenital hyperinsulinism.
Kuehnen, P. and Marquard, J. and Ernert, A. and Meissner, T. and Raile, K. and Wannenmacher, G. and Blankenstein, O.
Hormone Research in Paediatrics 78 (2): 106-112. September 2012

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.
Künkele, A. and De Preter, K. and Heukamp, L. and Thor, T. and Pajtler, K.W. and Hartmann, W. and Mittelbronn, M. and Grotzer, M.A. and Deubzer, H.E. and Speleman, F. and Schramm, A. and Eggert, A. and Schulte, J.H.
Neuro-Oncology 14 (7): 859-869. 1 July 2012

R-CHIE: a web server and R package for visualizing RNA secondary structures.
Lai, D. and Proctor, J.R. and Zhu, J.Y.A. and Meyer, I.M.
Nucleic Acids Research 40 (12): e95. July 2012

Translocation of sickle cell erythrocyte microRNAs into plasmodium falciparum inhibits parasite rranslation and contributes to malaria resistance.
Lamonte, G. and Philip, N. and Reardon, J. and Lacsina, J.R. and Majoros, W. and Chapman, L. and Thornburg, C.D. and Telen, M.J. and Ohler, U. and Nicchitta, C.V. and Haystead, T. and Chi, J.T.
Cell Host & Microbe 12 (2): 187-199. 16 August 2012

The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome.
Lamprecht, B. and Kreher, S. and Moebs, M. and Sterry, W. and Doerken, B. and Janz, M. and Assaf, C. and Mathas, S.
British Journal of Dermatology 167 (2): 240-246. August 2012

Stomatin-domain proteins.
Lapatsina, L. and Brand, J. and Poole, K. and Daumke, O. and Lewin, G.R.
European Journal of Cell Biology 91 (4): 240-245. April 2012

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann, S.M. and Krueger, C. and Park, B. and Derkow, K. and Rosenberger, K. and Baumgart, J. and Trimbuch, T. and Eom, G. and Hinz, M. and Kaul, D. and Habbel, P. and Kaelin, R. and Franzoni, E. and Rybak, A. and Nguyen, D. and Veh, R. and Ninnemann, O. and Peters, O. and Nitsch, R. and Heppner, F.L. and Golenbock, D. and Schott, E. and Ploegh, H.L. and Wulczyn, F.G. and Lehnardt, S.
Nature Neuroscience 15 (6): 827-835. June 2012

Thiamine is a substrate of organic cation transporters in Caco-2 cells.
Lemos, C. and Faria, A. and Meireles, M. and Martel, F. and Monteiro, R. and Calhau, C.
European Journal of Pharmacology 682 (1-3): 37-42. 5 May 2012

Prediction of protein secondary structure from circular dichroism using theoretically derived spectra.
Louis-Jeune, C. and Andrade-Navarro, M.A. and Perez-Iratxeta, C.
Proteins: Structure, Function, and Bioinformatics 80 (2): 374-381. February 2012

Continuous glucose monitoring in children, adolescents, and adults with type 1 diabetes mellitus: analysis from the prospective DPV diabetes documentation and quality management system from Germany and Austria.
Ludwig-Seibold, C.U. and Holder, M. and Rami, B. and Raile, K. and Heidtmann, B. and Holl, R.W.
Pediatric Diabetes 13 (1): 12-14. February 2012

Pattern and density of vascularization in mammalian testes, ovaries, and ovotestes.
Lupianez, D.G. and Real, F.M. and Dadhich, R.K. and Carmona, F.D. and Burgos, M. and Barrionuevo, F.J. and Jimenez, R.
Journal of Experimental Zoology Part B : Molecular and Developmental Evolution 318 (3): 170-181. May 2012

Cardiovascular medications in angiogenesis- how to avoid the sting in the tail.
Ma, C. and Wang, Q. and Man, Y. and Kemmner, W.
International Journal of Cancer 131 (6): 1249-1259. 15 September 2012

Sarcolemmal repair is a slow process and includes EHD2.
Marg, A. and Schoewel, V. and Timmel, T. and Schulze, A. and Shah, C. and Daumke, O. and Spuler, S.
Traffic 13 (9): 1286-1294. September 2012

The Lin28 cold-shock domain remodels pre-let-7 microRNA.
Mayr, F. and Schütz, A. and Dge, N. and Heinemann, U.
Nucleic Acids Research 40 (15): 7492-7506. 1 August 2012

In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes.
McCann, M. and Santos, A.L.S. and da Silva, B.A. and Romanos, M.T.V. and Pyrrho, A.S. and Devereux, M. and Kavanagh, K. and Fichtner, I. and Kellett, A.
Toxicology Research 1 (1): 47-54. July 2012

The transcriptional landscape of hematopoietic stem cell ontogeny.
McKinney-Freeman, S. and Cahan, P. and Li, H. and Lacadie, S.A. and Huang, H.T. and Curran, M. and Loewer, S. and Naveiras, O. and Kathrein, K.L. and Konantz, M. and Langdon, E.M. and Lengerke, C. and Zon, L.I. and Collins, J.J. and Daley, G.Q.
Cell Stem Cell 11 (5): 701-714. 2 November 2012

Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.
McNeill, B. and Perez-Iratxeta, C. and Mazerolle, C. and Furimsky, M. and Mishina, Y. and Andrade-Navarro, M.A. and Wallace, V.A.
Molecular and Cellular Neuroscience 49 (3): 333-340. March 2012

Nestin expression identifies ependymoma patients with poor outcome.
Milde, T. and Hielscher, T. and Witt, H. and Kool, M. and Mack, S.C. and Deubzer, H.E. and Oehme, I. and Lodrini, M. and Benner, A. and Taylor, M.D. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Witt, O. and Korshunov, A.
Brain Pathology 22 (6): 848-860. November 2012

HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.
Milde, T. and Lodrini, M. and Savelyeva, L. and Korshunov, A. and Kool, M. and Brueckner, L.M. and Antunes, A.S.L.M. and Oehme, I. and Pekrun, A. and Pfister, S.M. and Kulozik, A.E. and Witt, O. and Deubzer, H.E.
Journal of Neuro-Oncology 110 (3): 335-348. December 2012

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization.
Moren, B. and Shah, C. and Howes, M.T. and Schieber, N.L. and McMahon, H.T. and Parton, R.G. and Daumke, O. and Lundmark, R.
Molecular Biology of the Cell 23 (7): 1316-1329. 9 February 2012

Protective capacity of virus-specific T cell receptor (TCR)-transduced CD8 T cells in vivo.
Mueller, K. and von Maessenhausen, A. and Aichele, U. and Staerck, L. and Leisegang, M. and Uckert, W. and Pircher, H.
Journal of Virology 86 (19): 10866-10869. October 2012

p14ARF-induced apoptosis in p53-deficient cells is mediated by the BH3-only protein independent de-repression of Bak through down-regulation of Mcl-1 and Bcl-xL.
Muer, A. and Overkamp, T. and Gillissen, B. and Richter, A. and Pretzsch, T. and Milojkovic, A. and Doerken, B. and Daniel, P.T. and Hemmati, P.
Journal of Biological Chemistry 287 (21): 17343-17352. 18 May 2012

Diverse epigenetic strategies interact to control epidermal differentiation.
Mulder, K.W. and Wang, X. and Escriu, C. and Ito, Y. and Schwarz, R.F. and Gillis, J. and Sirokmany, G. and Donati, G. and Uribe-Lewis, S. and Pavlidis, P. and Murrell, A. and Markowetz, F. and Watt, F.M.
Nature Cell Biology 14 (7): 753-763. 24 June 2012

Natural antisense transcripts within pseudogenes: an EST survey.
Muro, E.M. and Andrade-Navarro, M.A.
In: Non-coding RNAs and epigenetic regulation of gene expression : drivers of natural selection. Caister Academic Press (U.K.), Norfolk, 99-108. ISBN 978-1-904455-94-3 February 2012

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Naba, A. and Clauser, K.R. and Hoersch, S. and Liu, H. and Carr, S.A. and Hynes, R.O.
Molecular & Cellular Proteomics 11 (4): M111.014647. 1 April 2012

Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Nagel, D. and Spranger, S. and Vincendeau, M. and Grau, M. and Raffegerst, S. and Kloo, B. and Hlahla, D. and Neuenschwander, M. and von Kries, J.P. and Hadian, K. and Doerken, B. and Lenz, P. and Lenz, G. and Schendel, D.J. and Krappmann, D.
Cancer Cell 22 (6): 825-837. 11 December 2012

CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.
Nakamoto, N. and Ebinuma, H. and Kanai, T. and Chu, P.S. and Ono, Y. and Mikami, Y. and Ojiro, K. and Lipp, M. and Love, P.E. and Saito, H. and Hibi, T.
Gastroenterology 142 (2): 366-376. February 2012

Predicting cell-type-specific gene expression from regions of open chromatin.
Natarajan, A. and Yardimci, G.G. and Sheffield, N.C. and Crawford, G.E. and Ohler, U.
Genome Research 22 (9): 1711-1722. September 2012

The immediate early gene Ier2 promotes tumor cell motility and metastasis, and predicts poor survival of colorectal cancer patients.
Neeb, A. and Wallbaum, S. and Novac, N. and Dukovic-Schulze, S. and Scholl, I. and Schreiber, C. and Schlag, P. and Moll, J. and Stein, U. and Sleeman, J.P.
Oncogene 31 (33): 3796-3806. August 2012

Evolutionary molecular medicine.
Nesse, R.M. and Ganten, D. and Gregory, T.R. and Omenn, G.S.
Journal of Molecular Medicine 90 (5): 509-522. May 2012

CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model.
Nguyen-Hoai, T. and Baldenhofer, G. and Ahmed, M.S. and Pham-Duc, M. and Gries, M. and Lipp, M. and Doerken, B. and Pezzutto, A. and Westermann, J.
Journal of Gene Medicine 14 (2): 128-137. February 2012

CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model.
Nguyen-Hoai, T. and Baldenhofer, G. and Sayed Ahmed, M.S. and Pham-Duc, M. and Vu, M.D. and Lipp, M. and Doerken, B. and Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 19 (1): 69-76. January 2012

CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: improved vaccine efficacy and a role for B cells as APC.
Nguyen-Hoai, T. and Hohn, O. and Vu, M.D. and Baldenhofer, G. and Sayed Ahmed, M.S. and Doerken, B. and Norley, S. and Lipp, M. and Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 19 (12): 880-887. December 2012

HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: gene gun is superior to jet injector in inducing CTL responses and protective immunity.
Nguyen-Hoai, T. and Kobelt, D. and Hohn, O. and Vu, M.D. and Schlag, P.M. and Doerken, B. and Norley, S. and Lipp, M. and Walther, W. and Pezzutto, A. and Westermann, J.
OncoImmunology 1 (9): 1537-1545. 1 December 2012

Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer.
Nitsche, U. and Rosenberg, R. and Balmert, A. and Schuster, T. and Slotta-Huspenina, J. and Herrmann, P. and Bader, F.G. and Friess, H. and Schlag, P.M. and Stein, U. and Janssen, K.P.
Annals of Surgery 256 (5): 763-771. November 2012

Treatment of experimental brain metastasis with MTO-liposomes: impact of fluidity and LRP-targeting on the therapeutic result.
Orthmann, A. and Zeisig, R. and Suess, R. and Lorenz, D. and Lemm, M. and Fichtner, I.
Pharmaceutical Research 29 (7): 1949-1959. July 2012

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.
Peterson, K.A. and Nishi, Y. and Ma, W. and Vedenko, A. and Shokri, L. and Zhang, X. and McFarlane, M. and Baizabal, J.M. and Junker, J.P. and van Oudenaarden, A. and Mikkelsen, T. and Bernstein, B.E. and Bailey, T.L. and Bulyk, M.L. and Wong, W.H. and McMahon, A.P.
Genes & Development 26 (24): 2802-2816. 15 December 2012

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
Petrakis, S. and Rasko, T. and Russ, J. and Friedrich, R.P. and Stroedicke, M. and Riechers, S.P. and Muehlenberg, K. and Moeller, A. and Reinhardt, A. and Vinayagam, A. and Schaefer, M.H. and Boutros, M. and Tricoire, H. and Andrade-Navarro, M.A. and Wanker, E.E.
PLoS Genetics 8 (8): e1002897. 16 August 2012

The protein expression landscape of the Arabidopsis root.
Petricka, J.J. and Schauer, M.A. and Megraw, M. and Breakfield, N.W. and Thompson, J.W. and Georgiev, S. and Soderblom, E.J. and Ohler, U. and Moseley, M.A. and Grossniklaus, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 109 (18): 6811-6818. 1 May 2012

In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.
Pichorner, A. and Sack, U. and Kobelt, D. and Kelch, I. and Arlt, F. and Smith, J. and Walther, W. and Schlag, P.M. and Stein, U.
Clinical and Experimental Metastasis 29 (6): 573-583. August 2012

Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells.
Ploetz, M. and Gillissen, B. and Hossini, A.M. and Daniel, P.T. and Eberle, J.
Cell Death and Differentiation 19 (12): 1928-1938. December 2012

Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK).
Ploetz, M. and Hossini, A.M. and Gillissen, B. and Daniel, P.T. and Stockfleth, E. and Eberle, J.
PLoS ONE 7 (4): e34549. 10 April 2012

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.
Rosario, M. and Schuster, S. and Juettner, R. and Parthasarathy, S. and Tarabykin, V. and Birchmeier, W.
Genes & Development 26 (15): 1743-1757. 1 August 2012

RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.
Sachs, R. and Max, K.E. and Heinemann, U. and Balbach, J.
RNA 18 (1): 65-76. January 2012

Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.
Sander, S. and Calado, D.P. and Srinivasan, L. and Koechert, K. and Zhang, B. and Rosolowski, M. and Rodig, S.J. and Holzmann, K. and Stilgenbauer, S. and Siebert, R. and Bullinger, L. and Rajewsky, K.
Cancer Cell 22 (2): 167-179. 14 August 2012

Burkitt lymphomagenesis linked to MYC plus PI3K in germinal center B cells.
Sander, S. and Rajewsky, K.
Oncotarget 3 (10): 1066-1067. 28 October 2012

Paired sage-microarray expression data sets reveal antisense transcripts differentially expressed in embryonic stem cell differentiation.
Sandie, R. and Porter, C.J. and Palidwor, G.A. and Price, F. and Krzyzanowski, P.M. and Muro, E.M. and Hoersch, S. and Smith, M. and Campbell, P.A. and Perez-Iratxeta, C. and Rudnicki, M.A. and Andrade-Navarro, M.A.
In: Computational Biology of Embryonic Stem Cells. Bentham Science (U.S.A.), Oak Park, 193-215. ISBN 978-1-608-05025-3 2012

HIPPIE: integrating protein interaction networks with experiment based quality scores.
Schaefer, M.H. and Fontaine, J.F. and Vinayagam, A. and Porras, P. and Wanker, E.E. and Andrade-Navarro, M.A.
PLoS ONE 7 (2): e31826. 14 February 2012

Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Schaefer, M.H. and Wanker, E.E. and Andrade-Navarro, M.A.
Nucleic Acids Research 40 (10): 4273-4287. 1 May 2012

Targeted tumor therapy with a fusion Protein of an antiangiogenic human recombinant scFv and yeast cytosine deaminase.
Schellmann, N. and Panjideh, H. and Fasold, P. and Bachran, D. and Bachran, C. and Deckert, P.M. and Fuchs, H.
Journal of Immunotherapy 35 (7): 570-578. September 2012

The inhibition of the integrin VLA-4 in MV3 melanoma cell binding by non-anticoagulant heparin derivatives.
Schlesinger, M. and Schmitz, P. and Zeisig, R. and Naggi, A. and Torri, G. and Casu, B. and Bendas, G.
Thrombosis Research 129 (5): 603-610. May 2012

Peptide linkage to the α-subunit of MHCII creates a stably inverted antigen presentation complex.
Schlundt, A. and Guenther, S. and Sticht, J. and Wieczorek, M. and Roske, Y. and Heinemann, U. and Freund, C.
Journal of Molecular Biology 423 (3): 294-302. 26 October 2012

Sex differences in the drug therapy for oncologic diseases.
Schmetzer, O. and Floercken, A.
Handbook of Experimental Pharmacology 214 (3): 411-442. 2012

Detection of circulating tumor-associated antigen depends on the domains recognized by the monoclonal antibodies used: N-terminal trimmed EpCAM-levels are much higher than untrimmed forms.
Schmetzer, O. and Moldenhauer, G. and Nicolaou, A. and Schlag, P. and Riesenberg, R. and Pezzutto, A.
Immunology Letters 143 (2): 184-192. 30 April 2012

SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer.
Schmid, F. and Burock, S. and Klockmeier, K. and Schlag, P.M. and Stein, U.
Molecular Cancer 11 (1): 49. 29 July 2012

Versorgungsforschung – Notwendigkeit und Chancen [Health service research - necessity and opportunity].
Schmitz, S. and Schlag, P.M.
Onkologe 18 (2): 102-104. February 2012

The liberation of women from the scourge of cervical cancer.
Schneider, A. and Schlag, P.M.
Onkologe 18 (1): 6-8. January 2012

Dysferlin-peptides reallocate mutated dysferlin thereby restoring function.
Schoewel, V. and Marg, A. and Kunz, S. and Overkamp, T. and Siegert Carrazedo, R. and Zacharias, U. and Daniel, P.T. and Spuler, S.
PLoS ONE 7 (11): e49603. 20 November 2012

CCR7 deficiency causes diarrhea associated with altered ion transport in colonocytes in the absence of overt colitis.
Schumann, M. and Winter, S. and Wichner, K. and May, C. and Kuehl, A.A. and Batra, A. and Siegmund, B. and Zeitz, M. and Schulzke, J.D. and Lipp, M. and Hoepken, U.E.
Mucosal Immunology 5 (4): 377-387. July 2012

Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells.
Schwarzer, R. and Doerken, B. and Jundt, F.
Leukemia 26 (4): 806-813. April 2012

Primary malignant tumors of the liver.
Settmacher, U. and Schlag, P.M.
Onkologe 18 (7): 570-572. July 2012

The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation.
Shabek, N. and Herman-Bachinsky, Y. and Buchsbaum, S. and Lewinson, O. and Haj-Yahya, M. and Hejjaoui, M. and Lashuel, H.A. and Sommer, T. and Brik, A. and Ciechanover, A.
Molecular Cell 48 (1): 87-97. 12 October 2012

The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Shah, S.P. and Roth, A. and Goya, R. and Oloumi, A. and Ha, G. and Zhao, Y. and Turashvili, G. and Ding, J. and Tse, K. and Haffari, G. and Bashashati, A. and Prentice, L.M. and Khattra, J. and Burleigh, A. and Yap, D. and Bernard, V. and McPherson, A. and Shumansky, K. and Crisan, A. and Giuliany, R. and Heravi-Moussavi, A. and Rosner, J. and Lai, D. and Birol, I. and Varhol, R. and Tam, A. and Dhalla, N. and Zeng, T. and Ma, K. and Chan, S.K. and Griffith, M. and Moradian, A. and Cheng, S.W.G. and Morin, G.B. and Watson, P. and Gelmon, K. and Chia, S. and Chin, S.F. and Curtis, C. and Rueda, O.M. and Pharoah, P.D. and Damaraju, S. and Mackey, J. and Hoon, K. and Harkins, T. and Tadigotla, V. and Sigaroudinia, M. and Gascard, P. and Tlsty, T. and Costello, J.F. and Meyer, I.M. and Eaves, C.J. and Wasserman, W.W. and Jones, S. and Huntsman, D. and Hirst, M. and Caldas, C. and Marra, M.A. and Aparicio, S.
Nature 486 (7403): 395-399. 21 June 2012

Interleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis.
Shalapour, S. and Deiser, K. and Kuehl, A.A. and Glauben, R. and Krug, S.M. and Fischer, A. and Sercan, O. and Chappaz, S. and Bereswill, S. and Heimesaat, M.M. and Loddenkemper, C. and Fromm, M. and Finke, D. and Haemmerling, G.J. and Arnold, B. and Siegmund, B. and Schueler, T.
PLoS ONE 7 (2): e31939. 27 February 2012

Morphology and ultrastructure of the chorioallantoic placenta of the Iberian mole (Talpa occidentalis) with special reference to heterophagous areolas and the nature of interhaemal barrier.
Siniza, S. and Lupianez, D.G. and Jimenez, R. and Zeller, U.
Journal of Anatomy 221 (2): 164-173. August 2012

Multiple sclerosis lesions and irreversible brain tissue damage: a comparative ultrahigh-field strength magnetic resonance imaging study.
Sinnecker, T. and Mittelstaedt, P. and Doerr, J. and Pfueller, C.F. and Harms, L. and Niendorf, T. and Paul, F. and Wuerfel, J.
Archives of Neurology 69 (6): 739-745. June 2012

The viral and cellular microRNA targetome in lymphoblastoid cell lines.
Skalsky, R.L. and Corcoran, D.L. and Gottwein, E. and Frank, C.L. and Kang, D. and Hafner, M. and Nusbaum, J.D. and Feederle, R. and Delecluse, H.J. and Luftig, M.A. and Tuschl, T. and Ohler, U. and Cullen, B.R.
PLoS Pathogens 8 (1): e1002484. 26 January 2012

Instruction of mesenchymal cell fate by the transcription factor C/EBPbeta.
Smink, J.J. and Leutz, A.
Gene 497 (1): 10-17. 10 April 2012

A TORway to osteolytic disease.
Smink, J.J. and Leutz, A.
Cell Cycle 11 (4): 637-638. 15 February 2012

Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis.
Smink, J.J. and Tunn, P.U. and Leutz, A.
Journal of Molecular Medicine 90 (1): 25-30. January 2012

Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: comparative analysis using six species of bathyergidae.
Smith, E.S.J. and Purfuerst, B. and Grigoryan, T. and Park, T.J. and Bennett, N.C. and Lewin, G.R.
Journal of Comparative Neurology 520 (12): 2785-2803. 15 August 2012

High prevalence and breast cancer predisposing role of the BLMc.1642 C>T (Q548X) mutation in Russia.
Sokolenko, A.P. and Iyevleva, A.G. and Preobrazhenskaya, E.V. and Mitiushkina, N.V. and Abysheva, S.N. and Suspitsin, E.N. and Kuligina, E.S. and Gorodnova, T.V. and Pfeifer, W. and Togo, A.V. and Turkevich, E.A. and Ivantsov, A.O. and Voskresenskiy, D.V. and Dolmatov, G.D. and Bit-Sava, E.M. and Matsko, D.E. and Semiglazov, V.F. and Fichtner, I. and Larionov, A.A. and Kuznetsov, S.G. and Antoniou, A.C. and Imyanitov, E.N.
International Journal of Cancer 130 (12): 2867-2873. 15 June 2012

Caipirini: using gene sets to rank literature.
Soldatos, T.G. and O'Donoghue, S.I. and Satagopam, V.P. and Barbosa-Silva, A. and Pavlopoulos, G.A. and Wanderley-Nogueira, A.C. and Soares-Cavalcanti, N.M. and Schneider, R.
BioData Mining 5 (1): 1. 1 February 2012

Predictive factors for the benefit of perioperative FOLFOX for resectable liver metastasis in colorectal cancer patients (EORTC Intergroup trial 40983).
Sorbye, H. and Mauer, M. and Gruenberger, T. and Glimelius, B. and Poston, G.J. and Schlag, P.M. and Rougier, P. and Bechstein, W.O. and Primrose, J.N. and Walpole, E.T. and Finch-Jones, M. and Jaeck, D. and Mirza, D. and Parks, R.W. and Collette, L. and Cutsem, E.V. and Scheithauer, W. and Lutz, M.P. and Nordlinger, B.
Annals of Surgery 255 (3): 534-539. March 2012

Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M. and Besser, D. and Benitah, S.A.
EMBO Reports 13 (1): 9-11. January 2012

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.
Spranger, S. and Jeremias, I. and Wilde, S. and Leisegang, M. and Staerck, L. and Mosetter, B. and Uckert, W. and Heemskerk, M.H.M. and Schendel, D.J. and Frankenberger, B.
Blood 119 (15): 3440-3449. 12 April 2012

The hok mRNA family.
Steif, A. and Meyer, I.M.
RNA Biology 9 (12): 1399-1404. 1 December 2012

Circulating MACC1 transcripts in colorectal cancer patient plasma predict metastasis and prognosis.
Stein, U. and Burock, S. and Herrmann, P. and Wendler, I. and Niederstrasser, M. and Wernecke, K.D. and Schlag, P.M.
PLoS ONE 7 (11): e49249. 14 November 2012

Impact of mutant beta-catenin on ABCB1 expression and therapy response in colon cancer cells.
Stein, U. and Fleuter, C. and Siegel, F. and Smith, J. and Kopacek, A. and Scudiero, D.A. and Hite, K.M. and Schlag, P.M. and Shoemaker, R.H. and Walther, W.
British Journal of Cancer 106 (8): 1395-1405. 10 April 2012

Small molecule screening in zebrafish: swimming in potential drug therapies.
Tamplin, O.J. and White, R.M. and Jing, L. and Kaufman, C.K. and Lacadie, S.A. and Li, P. and Taylor, A.M. and Zon, L.I.
Wiley Interdisciplinary Reviews: Developmental Biology 1 (3): 459-468. May 2012

NIH-defined graft-versus-host disease after reduced intensity or myeloablative conditioning in patients with acute myeloid leukemia.
Terwey, T.H. and Vega-Ruiz, A. and Hemmati, P.G. and Martus, P. and Dietz, E. and le Coutre, P. and Massenkeil, G. and Doerken, B. and Arnold, R.
Leukemia 26 (3): 536-542. March 2012

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.
Vaeth, M. and Schliesser, U. and Mueller, G. and Reissig, S. and Satoh, K. and Tuettenberg, A. and Jonuleit, H. and Waisman, A. and Mueller, M.R. and Serfling, E. and Sawitzki, B.S. and Berberich-Siebelt, F.
Proceedings of the National Academy of Sciences of the United States of America 109 (40): 16258-16263. 2 October 2012

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes.
Volcic, M. and Karl, S. and Baumann, B. and Salles, D. and Daniel, P. and Fulda, S. and Wiesmueller, L.
Nucleic Acids Research 40 (1): 181-195. January 2012

Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
Volz, T. and Luetgehetmann, M. and Allweiss, L. and Warlich, M. and Bierwolf, J. and Pollok, J.M. and Petersen, J. and Matthes, E. and Dandri, M.
Antiviral Therapy 17 (4): 623-631. 27 February 2012

Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
Voutilainen, M. and Lindfors, P.H. and Lefebvre, S. and Ahtiainen, L. and Fliniaux, I. and Rysti, E. and Murtoniemi, M. and Schneider, P. and Schmidt-Ullrich, R. and Mikkola, M.L.
Proceedings of the National Academy of Sciences of the United States of America 109 (15): 5744-5749. 10 April 2012

Expression of coagulation factors and their receptors in tumor tissue and coagulation factor upregulation in peripheral blood of patients with cerebral carcinoma metastases.
Walter, J. and Handel, L.L. and Brodhun, M. and van Rossum, D. and Hanisch, U.K. and Liebmann, L. and Heppner, F. and Goldbrunner, R. and Koch, A. and Kuhn, S.A.
Journal of cancer research and clinical oncology 138 (1): 141-151. January 2012

Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors.
Walther, W. and Petkov, S. and Kuvardina, O.N. and Aumann, J. and Kobelt, D. and Fichtner, I. and Lemm, M. and Piontek, J. and Blasig, I.E. and Stein, U. and Schlag, P.M.
Gene Therapy 19 (5): 494-503. May 2012

In-vivo tumor imaging using a novel RNAi-based detection mechanism.
Wan, K. and Ebert, B. and Voigt, J. and Wang, Q. and Dai, Y. and Haag, R. and Kemmner, W.
Nanomedicine 8 (4): 393-398. May 2012

The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer.
White, N.M.A. and Youssef, Y.M. and Fendler, A. and Stephan, C. and Jung, K. and Yousef, G.M.
Biological Chemistry 393 (5): 379-389. May 2012

Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition.
Wilde, S. and Sommermeyer, D. and Leisegang, M. and Frankenberger, B. and Mosetter, B. and Uckert, W. and Schendel, D.J.
Journal of Immunology 189 (2): 598-605. 15 July 2012

Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma or leukemia.
Witt, O. and Milde, T. and Deubzer, H.E. and Oehme, I. and Witt, R. and Kulozik, A. and Eisenmenger, A. and Abel, U. and Karapanagiotou-Schenkel, I.
Klinische Padiatrie 224 (6): 398-403. October 2012

Intrahepatic transplantation of CD34(+) cord blood stem cells into newborn and adult NOD/SCID mice induce differential organ engraftment.
Wulf-Goldenberg, A. and Keil, M. and Fichtner, I. and Eckert, K.
Tissue & Cell 44 (2): 80-86. April 2012

Anton Sticker (1861-1944) und das Sticker-Sarkom des Hundes. Ein aktuelles Modell fuer infektioese Krebszellen [Anton Sticker (1861-1944) and the Sticker's sarcoma of dogs. A current model for infectious cancer cells].
Wunderlich, V.
Tieraerztliche Praxis Kleintiere 40 (6): 432-437. 2012

Peyton Rous: a centennial tribute to the founding father of cancer virology.
Wunderlich, V. and Kunze, P.
In: Cancer Associated Viruses. Current Cancer Research . Springer Science and Business Media, New York, 1-23. ISBN 978-1-4419-9999-3 2012

The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.
Yndestad, A. and Finsen, A.V. and Ueland, T. and Husberg, C. and Dahl, C.P. and Oie, E. and Vinge, L.E. and Sjaastad, I. and Sandanger, O. and Ranheim, T. and Dickstein, K. and Kjekshus, J. and Damas, J.K. and Fiane, A.E. and Hilfiker-Kleiner, D. and Lipp, M. and Gullestad, L. and Christensen, G. and Aukrust, P.
PLoS ONE 7 (3): e33038. 12 March 2012

Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.
Yu, J. and Valerius, M.T. and Duah, M. and Staser, K. and Hansard, J.K. and Guo, J.J. and McMahon, J. and Vaughan, J. and Faria, D. and Georgas, K. and Rumballe, B. and Ren, Q. and Krautzberger, A.M. and Junker, J.P. and Thiagarajan, R.D. and Machanick, P. and Gray, P.A. and van Oudenaarden, A. and Rowitch, D.H. and Stiles, C.D. and Ma, Q. and Grimmond, S.M. and Bailey, T.L. and Little, M.H. and McMahon, A.P.
Development 139 (10): 1863-1873. May 2012

Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling.
Yuan, Y. and Failmezger, H. and Rueda, O.M. and Ali, H.R. and Graef, S. and Chin, S.F. and Schwarz, R.F. and Curtis, C. and Dunning, M.J. and Bardwell, H. and Johnson, N. and Doyle, S. and Turashvili, G. and Provenzano, E. and Aparicio, S. and Caldas, C. and Markowetz, F.
Science Translational Medicine 4 (157): 157ra143. 24 October 2012

Immune surveillance and therapy of lymphomas driven by Epstein-Barr-Virus protein LMP1 in a mouse model.
Zhang, B. and Kracker, S. and Yasuda, T. and Casola, S. and Vannemann, M. and Hoemig-Hoeltzel, C. and Wang, Z. and Derudder, E. and Li, S. and Chakraborty, T. and Cotter, S.E. and Koyama, S. and Currie, T. and Freeman, G.J. and Kutok, J.L. and Rodig, S.J. and Dranoff, G. and Rajewsky, K.
Cell 148 (4): 739-751. 17 February 2012

The primary transcriptome of barley chloroplasts: numerous noncoding RNAs and the dominating role of the plastid-encoded RNA polymerase.
Zhelyazkova, P. and Sharma, C.M. and Foerstner, K.U. and Liere, K. and Vogel, J. and Boerner, T.
Plant Cell 24 (1): 123-136. January 2012

T cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing.
Zhou, Q. and Schneider, I.C. and Edes, I. and Honegger, A. and Bach, P. and Schoenfeld, K. and Schambach, A. and Wels, W.S. and Kneissl, S. and Uckert, W. and Buchholz, C.J.
Blood 120 (22): 4334-4342. 22 November 2012

The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
von Eyss, B. and Maaskola, J. and Memczak, S. and Möllmann, K. and Schuetz, A. and Loddenkemper, C. and Tanh, M.D. and Otto, A. and Muegge, K. and Heinemann, U. and Rajewsky, N. and Ziebold, U.
EMBO Journal 31 (4): 972-985. 15 February 2012

2011

Cancer risk evaluation: methods and trends.
Obe, G. and Jandrig, B. and Marchant, G.E. and Schuetz, H. and Wiedemann, P.M., eds.
Wiley-Blackwell (Germany), Weinheim. ISBN 978-3-527-32753-9 2011

Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K. and Buschow, C. and Herrmann, A. and Milojkovic, A. and Loddenkemper, C. and Kammertoens, T. and Daniel, P. and Yu, H. and Charo, J. and Blankenstein, T.
Cancer Cell 20 (6): 755-767. 13 December 2011

Steady state migratory RelB(+) Langerin(+) dermal dendritic cells mediate peripheral induction of antigen-specific CD4(+) CD25(+) Foxp3(+) regulatory T cells.
Azukizawa, H. and Doehler, A. and Kanazawa, N. and Nayak, A. and Lipp, M. and Malissen, B. and Autenrieth, I. and Katayama, I. and Riemann, M. and Weih, F. and Berberich-Siebelt, F. and Lutz, M.B.
European Journal of Immunology 41 (5): 1420-1434. May 2011

Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells.
Bachmeier, B. and Fichtner, I. and Killian, P.H. and Kronski, E. and Pfeffer, U. and Efferth, T.
PLoS ONE 6 (5): e20550. 26 May 2011

Protein dislocation from the ER.
Bagola, K. and Mehnert, M. and Jarosch, E. and Sommer, T.
Biochimica et Biophysica Acta - Biomembranes 1808 (3): 925-936. March 2011

PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries.
Barbosa-Silva, A. and Fontaine, J.F. and Donnard, E.R. and Stussi, F. and Ortega, J.M. and Andrade-Navarro, M.A.
BMC Bioinformatics 12 (1): 435. 9 November 2011

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.
Bergman, A.M. and Adema, A.D. and Balzarini, J. and Bruheim, S. and Fichtner, I. and Noordhuis, P. and Fodstad, O. and Myhren, F. and Sandvold, M.L. and Hendriks, H.R. and Peters, G.J.
Investigational New Drugs 29 (3): 456-466. June 2011

Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.
Bijnsdorp, I.V. and Schwendener, R.A. and Schott, H. and Fichtner, I. and Smid, K. and Laan, A.C. and Schott, S. and Losekoot, N. and Honeywell, R.J. and Peters, G.J.
Investigational New Drugs 29 (2): 248-257. April 2011

Stem cells: Orphan receptors find a home.
Birchmeier, W.
Nature 476 (7360): 287-288. 18 August 2011

Eight cycles of escalated-dose BEACOPP compared with four cycles of escalated-dose BEACOPP followed by four cycles of baseline-dose BEACOPP with or without radiotherapy in patients with advanced-stage Hodgkin's lymphoma: final analysis of the HD12 trial of the German Hodgkin study group.
Borchmann, P. and Haverkamp, H. and Diehl, V. and Cerny, T. and Markova, J. and Ho, A.D. and Eich, H.T. and Mueller-Hermelink, H.K. and Kanz, L. and Greil, R. and Rank, A. and Paulus, U. and Smardova, L. and Huber, C. and Doerken, B. and Nerl, C. and Krause, S.W. and Mueller, R.P. and Fuchs, M. and Engert, A.
Journal of Clinical Oncology 29 (32): 4234-4342. 10 November 2011

Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Bothmer, A. and Robbiani, D.F. and Di Virgilio, M. and Bunting, S.F. and Klein, I.A. and Feldhahn, N. and Barlow, J. and Chen, H.T. and Bosque, D. and Callen, E. and Nussenzweig, A. and Nussenzweig, M.C.
Molecular Cell 42 (3): 319-329. 6 May 2011

A stele-enriched gene regulatory network in the Arabidopsis root.
Brady, S.M. and Zhang, L. and Megraw, M. and Martinez, N.J. and Jiang, E. and Yi, C.S. and Liu, W. and Zeng, A. and Taylor-Teeples, M. and Kim, D. and Ahnert, S. and Ohler, U. and Ware, D. and Walhout, A.J.M. and Benfey, P.N.
Molecular Systems Biology 7 : 459. 18 January 2011

BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, F.H. and Wiese, M. and Zatula, N. and Grigoryan, T. and Dai, Y. and Fritzmann, J. and Birchmeier, W.
Gastroenterology 141 (4): 1359-1370. October 2011

Tumor rejection by local interferon gamma induction in established tumors is associated with blood vessel destruction and necrosis.
Briesemeister, D. and Sommermeyer, D. and Loddenkemper, C. and Loew, R. and Uckert, W. and Blankenstein, T. and Kammertoens, T.
International Journal of Cancer 128 (2): 371-378. 15 January 2011

Expression of protein complexes using multiple E. coli protein co-expression systems: a benchmarking study.
Busso, D. and Peleg, Y. and Heidebrecht, T. and Romier, C. and Jacobovitch, Y. and Dantes, A. and Salim, L. and Troesch, E. and Schuetz, A. and Heinemann, U. and Folkers, G.E. and Geerlof, A. and Wilmanns, M. and Polewacz, A. and Quedenau, C. and Büssow, K. and Adamson, R. and Blagova, E. and Walton, J. and Cartwright, J.L. and Bird, L.E. and Owens, R.J. and Berrow, N.S. and Wilson, K.S. and Sussman, J.L. and Perrakis, A. and Celie, P.H.
Journal of Structural Biology 175 (2): 159-170. August 2011

Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly (ethylene glycol) shell.
Calderon, M. and Welker, P. and Licha, K. and Fichtner, I. and Graeser, R. and Haag, R. and Kratz, F.
Journal of Controlled Release 151 (3): 295-301. 10 May 2011

Visualizing the dynamic of adoptively transferred T cells during the rejection of large established tumors.
Charo, J. and Perez, C. and Buschow, C. and Jukica, A. and Czeh, M. and Blankenstein, T.
European Journal of Immunology 41 (11): 3187-3197. November 2011

Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells.
Chyou, S. and Benahmed, F. and Chen, J. and Kumar, V. and Tian, S. and Lipp, M. and Lu, T.T.
Journal of Immunology 187 (11): 5558-5567. 2 December 2011

The prevalence of TNFα-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay.
Coel Arslan, S. and Scheidereit, C.
PLoS ONE 6 (10): e26069. 10 October 2011

A roadmap to generate renewable protein binders to the human proteome.
Colwill, K. and Graeslund, S.
Nature Methods 8 (7): 551-558. 15 May 2011

PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data.
Corcoran, D.L. and Georgiev, S. and Mukherjee, N. and Gottwein, E. and Skalsky, R.L. and Keene, J.D. and Ohler, U.
Genome Biology 12 (8): R79. 18 August 2011

Expression of genes controlling testicular development in adult testis of the seasonally breeding iberian mole.
Dadhich, R.K. and Barrionuevo, F.J. and Lupianez, D.G. and Real, F.M. and Burgos, M. and Jimenez, R.
Sexual Development 5 (2): 77-88. March 2011

Structural insights into membrane fusion at the endoplasmic reticulum.
Daumke, O. and Praefcke, G.J.
Proceedings of the National Academy of Sciences of the United States of America 108 (6): 2175-2176. 8 February 2011

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.
Di Micco, R. and Sulli, G. and Dobreva, M. and Liontos, M. and Botrugno, O.A. and Gargiulo, G. and dal Zuffu, R. and Matti, V. and d'Ario, G. and Montani, E. and Mercurio, C. and Hahn, W.C. and Gorgoulis, V. and Minucci, S. and d'Adda di Fagagna, F.
Nature Cell Biology 13 (3): 292-302. March 2011

Preimplantation development regulatory pathway construction through a text-mining approach.
Donnard, E. and Barbosa-Silva, A. and Guedes, R.L. and Fernandes, G.R. and Velloso, H. and Kohn, M.J. and Andrade-Navarro, M.A. and Ortega, J.M.
BMC Genomics 12 (Suppl 4): S3. 22 December 2011

Efficient generation of B lymphocytes by recognition of self-antigens.
Eschbach, C. and Bach, M.P. and Fidler, I. and Pelanda, R. and Koehler, F. and Rajewsky, K. and Jumaa, H.
European Journal of Immunology 41 (8): 2397-2403. August 2011

Crystal structure of nucleotide-free dynamin.
Faelber, K. and Posor, Y. and Gao, S. and Held, M. and Roske, Y. and Schulze, D. and Haucke, V. and Noe, F. and Daumke, O.
Nature 477 (7366): 556-560. 29 September 2011

Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli, U.M. and Ullrich, K. and Stuehmer, T. and Holien, T. and Koechert, K. and Holt, R.U. and Bruland, O. and Chatterjee, M. and Nogai, H. and Lenz, G. and Shaughnessy, J.D. and Mathas, S. and Sundan, A. and Bargou, R.C. and Doerken, B. and Borset, M. and Janz, M.
Oncogene 30 (28): 3198-3206. 14 July 2011

The antiangiogenic and antitumoral activity of titanocene Y* in vivo.
Fichtner, I. and Behrens, D. and Claffey, J. and Deally, A. and Gleeson, B. and Patil, S. and Weber, H. and Tacke, M.
Letters in Drug Design & Discovery 8 (4): 302-307. May 2011

Hepatic arterial infusion chemotherapy for liver metastases from gastric cancer: an analysis in western patients.
Floercken, A. and Schaefer, C. and Bichev, D. and Breithaupt, K. and Dogan, Y. and Schumacher, G. and Gebauer, B. and Riess, H. and Doerken, B. and Thuss-Patience, P.C.
Tumori 97 (1): 19-24. January 2011

THBS4, a novel stromal molecule of diffuse-type gastric adenocarcinomas, identified by transcriptome-wide expression profiling.
Foerster, S. and Gretschel, S. and Joens, T. and Yashiro, M. and Kemmner, W.
Modern Pathology 24 (10): 1390-1403. October 2011

PDBpaint, a visualization webservice to tag protein structures with sequence annotations.
Fournier, D. and Andrade-Navarro, M.A.
Bioinformatics 27 (18): 2605-2606. 15 September 2011

Integrated microfluidic platform for the electrochemical detection of breast cancer markers in patient serum samples.
Fragoso, A. and Latta, D. and Laboria, N. and von Germar, F. and Hansen-Hagge, T.E. and Kemmner, W. and Gaertner, C. and Klemm, R. and Drese, K.S. and O'Sullivan, C.K.
Lab on a Chip 11 (4): 625-631. 21 February 2011

Associations between media consumption habits, physical activity, socioeconomic status, and glycemic control in children, adolescents, and young adults with type 1 diabetes.
Galler, A. and Lindau, M. and Ernert, A. and Thalemann, R. and Raile, K.
Diabetes Care 34 (11): 2356-2359. November 2011

The Chriz-Z4 complex recruits JIL-1 to polytene chromosomes, a requirement for interband-specific phosphorylation of H3S10.
Gan, M. and Moebus, S. and Eggert, H. and Saumweber, H.
Journal of Biosciences 36 (3): 425-438. August 2011

Structure of myxovirus resistance protein A reveals intra- and intermolecular domain interactions required for the antiviral function.
Gao, S. and von der Malsburg, A. and Dick, A. and Faelber, K. and Schroeder, G.F. and Haller, O. and Kochs, G. and Daumke, O.
Immunity 35 (4): 514-525. 28 October 2011

Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.
Gazumyan, A. and Timachova, K. and Yuen, G. and Siden, E. and Di Virgilio, M. and Woo, E.M. and Chait, B.T. and Reina San-Martin, B. and Nussenzweig, M.C. and McBride, K.M.
Molecular and Cellular Biology 31 (3): 442-429. February 2011

Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S. and Riemke, P. and Schoenheit, J. and Lenze, D. and Stumm, J. and Hoogenkamp, M. and Lagendijk, A. and Heinz, S. and Bonifer, C. and Bakkers, J. and Abdelilah-Seyfried, S. and Hummel, M. and Rosenbauer, F.
Blood 118 (8): 2275-2284. 25 August 2011

The impact of short-term psycho-oncological interventions on the psychological outcome of cancer patients of a surgical-oncology department - A randomised controlled study.
Goerling, U. and Foerg, A. and Sander, S. and Schramm, N. and Schlag, P.M.
European Journal of Cancer 47 (13): 2009-2014. September 2011

Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines.
Gottwein, E. and Corcoran, D.L. and Mukherjee, N. and Skalsky, R.L. and Hafner, M. and Nusbaum, J.D. and Shamulailatpam, P. and Love, C.L. and Dave, S.S. and Tuschl, T. and Ohler, U. and Cullen, B.R.
Cell Host & Microbe 10 (5): 515-526. 17 November 2011

Applications of high-throughput sequencing.
Goya, R. and Meyer, I.M. and Marra, M.A.
In: Bioinformatics for High Throughput Sequencing. Springer (U.S.A.), 27-53. ISBN 978-1-4614-0781-2 22 September 2011

Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level.
Graupner, V. and Alexander, E. and Overkamp, T. and Rothfuss, O. and De Laurenzi, V. and Gillissen, B.F. and Daniel, P.T. and Schulze-Osthoff, K. and Essmann, F.
Cell Death and Differentiation 18 (7): 1130-1139. July 2011

A multichannel time-domain scanning fluorescence mammograph: Performance assessment and first in vivo results.
Grosenick, D. and Hagen, A. and Steinkellner, O. and Poellinger, A. and Burock, S. and Schlag, P.M. and Rinneberg, H. and Macdonald, R.
Review of Scientific Instruments 82 (2): 1024302. February 2011

Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.
Haeaerae, O. and Fujimori, S. and Schmidt-Ullrich, R. and Hartmann, C. and Thesleff, I. and Mikkola, M.L.
Development 138 (13): 2681-2691. July 2011

Alterations of pre-mRNA splicing in human inflammatory bowel disease.
Haesler, R. and Kerick, M. and Mah, N. and Hultschig, C. and Richter, G. and Bretz, F. and Sina, C. and Lehrach, H. and Nietfeld, W. and Schreiber, S. and Rosenstiel, P.
European Journal of Cell Biology 90 (6-7): 603-611. June 2011

Malt1-dependent RelB cleavage promotes canonical NF-κB activation in lymphocytes and lymphoma cell lines.
Hailfinger, S. and Nogai, H. and Pelzer, C. and Jaworski, M. and Cabalzar, K. and Charton, J.E. and Guzzardi, M. and Decaillet, C. and Grau, M. and Doerken, B. and Lenz, P. and Lenz, G. and Thome, M.
Proceedings of the National Academy of Sciences of the United States of America 108 (35): 14596-14601. 30 August 2011

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash, A.M. and Kappel, L.W. and Yim, N.L. and Nejat, R.A. and Goldberg, G.L. and Smith, O.M. and Rao, U.K. and Dykstra, L. and Na, I.K. and Holland, A.M. and Dudakov, J.A. and Liu, C. and Murphy, G.F. and Leonard, W.J. and Heller, G. and van den Brink, M.R.M.
Blood 118 (2): 446-455. 14 July 2011

A modified EBMT risk score predicts the outcome of patients with acute myeloid leukemia receiving allogeneic stem cell transplants.
Hemmati, P.G. and Terwey, T.H. and le Coutre, P. and Vuong, L.G. and Massenkeil, G. and Doerken, B. and Arnold, R.
European Journal of Haematology 86 (4): 305-316. April 2011

CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programs in neuroblastoma cells.
Henrich, K.O. and Bauer, T. and Schulte, J. and Ehemann, V. and Deubzer, H. and Gogolin, S. and Muth, D. and Fischer, M. and Benner, A. and König, R. and Schwab, M. and Westermann, F.
Cancer Research 71 (8): 3142-3151. 15 April 2011

Yos9p assists in the degradation of certain non-glycosylated proteins from the endoplasmic reticulum.
Jaenicke, L.A. and Brendebach, H. and Selbach, M. and Hirsch, C.
Molecular Biology of the Cell 22 (16): 2937-2945. August 2011

Models of cancer development: Genetic and environmental influences.
Jandrig, B.
In: Cancer Risk Evaluation: Methods and Trends. Wiley-VCH (Germany), Weinheim, Germany, 9-24. ISBN 9783527327539 20 April 2011

Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H. and Kase, J. and Doerr, J.R. and Milanovic, M. and Lenze, D. and Grau, M. and Beuster, G. and Ji, S. and Reimann, M. and Lenz, P. and Hummel, M. and Doerken, B. and Lenz, G. and Scheidereit, C. and Schmitt, C.A. and Lee, S.
Genes & Development 25 (20): 2137-2146. 15 October 2011

Virulence evolution of the human pathogen Neisseria meningitidis by recombination in the core and accessory genome.
Joseph, B. and Schwarz, R.F. and Linke, B. and Blom, J. and Becker, A. and Claus, H. and Goesmann, A. and Frosch, M. and Mueller, T. and Vogel, U. and Schoen, C.
PLoS ONE 6 (4): e18441. 26 April 2011

Transcriptomics and cancer risk assessment.
Kemmner, W.
In: Cancer risk evaluation : methods and trends. Wiley-VCH, Weinheim, 195-205. ISBN 9783527327539 27 April 2011

Long-term follow-up of patients with Philadelphia chromosome-positive chronic myeloid leukemia after stem cell mobilization under imatinib.
Kim, T.D. and Schwarz, M. and Kreuzer, K.A. and Kaeda, J. and Movassaghi, K. and Grille, P. and Daniel, P.T. and Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 52 (3): 517-520. March 2011

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes.
Klein, I.A. and Resch, W. and Jankovic, M. and Oliveira, T. and Yamane, A. and Nakahashi, H. and Di Virgilio, M. and Bothmer, A. and Nussenzweig, A. and Robbiani, D.F. and Casellas, R. and Nussenzweig, M.C.
Cell 147 (1): 95-106. 30 September 2011

Critical role of PI3K signaling for NF-κB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.
Kloo, B. and Nagel, D. and Pfeifer, M. and Grau, M. and Duewel, M. and Vincendeau, M. and Doerken, B. and Lenz, P. and Lenz, G. and Krappmann, D.
Proceedings of the National Academy of Sciences of the United States of America 108 (1): 272-277. 4 January 2011

High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.
Koechert, K. and Ullrich, K. and Kreher, S. and Aster, J.C. and Kitagawa, M. and Joehrens, K. and Anagnostopoulos, I. and Jundt, F. and Lamprecht, B. and Zimber-Strobl, U. and Stein, H. and Janz, M. and Doerken, B. and Mathas, S.
Oncogene 30 (15): 1831-1840. 14 April 2011

Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas.
Kretschmer, C. and Conradi, A. and Kemmner, W. and Sterner-Kock, A.
Cellular Oncology 34 (5): 419-434. 6 October 2011

Identification of early molecular markers for breast cancer.
Kretschmer, C. and Sterner-Kock, A. and Siedentopf, F. and Schoenegg, W. and Schlag, P.M. and Kemmner, W.
Molecular Cancer 10 (1): 15. 11 February 2011

Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells.
Kuerbitz, C. and Heise, D. and Redmer, T. and Goumas, F. and Arlt, A. and Lemke, J. and Rimbach, G. and Kalthoff, H. and Trauzold, A.
Cancer Science 102 (4): 728-734. April 2011

The ERGonomics of hematopoietic stem cell self-renewal.
Lacadie, S.A. and Zon, L.I.
Genes & Development 25 (4): 289-293. 15 February 2011

Automatic calibration of 3D ultrasound probes.
Lange, T. and Kraft, S. and Eulenstein, S. and Lamecker, H. and Schlag, P.M.
In: Workshops Bildverarbeitung fur die Medizin: Algorithmen - Systeme - Anwendungen, BVM 2011, 20-22 Mar 2011, Luebeck, Germany. 13 March 2011

Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation.
Larsen, K.O. and Yndestad, A. and Sjaastad, I. and Loberg, E.M. and Goverud, I.L. and Halvorsen, B. and Jia, J. and Andreassen, A.K. and Husberg, C. and Jonasson, S. and Lipp, M. and Christensen, G. and Aukrust, P. and Skjonsberg, O.H.
American Journal of Physiology Lung Cellular and Molecular Physiology 301 (1): L50-L59. July 2011

Severe peripheral arterial disease during nilotinib therapy.
Le Coutre, P. and Rea, D. and Abruzzese, E. and Dombret, H. and Trawinska, M.M. and Herndlhofer, S. and Doerken, B. and Valent, P.
Journal of the National Cancer Institute 103 (17): 1347-1348. 7 September 2011

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M. and Perrod, C. and Hoogenkamp, M. and Ghani, S. and Assi, S. and Heinz, S. and Wilson, N.K. and Follows, G. and Schoenheit, J. and Vockentanz, L. and Mosamam, A. and Chen, W. and Tenen, D.G. and Westhead, D.R. and Goettgens, B. and Bonifer, C. and Rosenbauer, F.
Blood 117 (10): 2827-2838. 10 March 2011

The Myc/macrophage tango: Oncogene-induced senescence, Myc style.
Lee, S. and Schmitt, C.A. and Reimann, M.
Seminars in Cancer Biology 21 (6): 377-384. December 2011

„Deep sequencing“ und praediktive Modellierung als Konzept therapeutischer Entscheidungsfindungen in der Onkologie [Deep sequencing and predictive modeling as a concept for therapeutic decision-making in oncology].
Lehrach, H. and Schaefer, R. and Schlag, P. M.
Onkologe 17 (6): 477-486. June 2011

Assessing the utility of thermodynamic features for microRNA target prediction under relaxed seed and no conservation requirements.
Lekprasert, P. and Mayhew, M. and Ohler, U.
PLoS ONE 6 (6): e20622. 6 June 2011

Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs.
Leutz, A. and Pless, O. and Lappe, M. and Dittmar, G. and Kowenz-Leutz, E.
Transcription 2 (1): 3-8. January 2011

Neuroblastoma imaging.
Ley, S. and Ley-Zaporozhan, J. and Günther, P. and Deubzer, H.E. and Witt, O. and Schenk, J.P.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 183 (3): 217-225. March 2011

Staphylococcus aureus physiological growth limitations: insights from flux calculations built on proteomics and external metabolite data.
Liang, C. and Liebeke, M. and Schwarz, R. and Zuehlke, D. and Fuchs, S. and Menschner, L. and Engelmann, S. and Wolz, C. and Jaglitz, S. and Bernhardt, J. and Hecker, M. and Lalk, M. and Dandekar, T.
Proteomics 11 (10): 1915-1935. May 2011

Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose.
Licht, A. and Bulut, H. and Scheffel, F.M. and Daumke, O. and Wehmeier, U.F. and Saenger, W. and Schneider, E. and Vahedi-Faridi, A.
Journal of Molecular Biology 406 (1): 92-105. 11 February 2011

Tissue specific subnetworks and characteristics of publicly available human protein interaction databases.
Lopes, T.J. and Schaefer, M. and Shoemaker, J. and Matsuoka, Y. and Fontaine, J.F. and Neumann, G. and Andrade-Navarro, M.A. and Kawaoka, Y. and Kitano, H.
Bioinformatics 27 (17): 2414-2421. 1 September 2011

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.
Lu, S.X. and Kappel, L.W. and Charbonneau-Allard, A.M. and Atallah, R. and Holland, A.M. and Turbide, C. and Hubbard, V.M. and Rotolo, J.A. and Smith, M. and Suh, D. and King, C. and Rao, U.K. and Yim, N. and Bautista, J.L. and Jenq, R.R. and Penack, O. and Na, I.K. and Liu, C. and Murphy, G. and Alpdogan, O. and Blumberg, R.S. and Macian, F. and Holmes, K.V. and Beauchemin, N. and van den Brink, M.R.M.
PLoS ONE 6 (7): e21611. 6 July 2011

In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans.
Ma, L. and Tan, Z. and Teng, Y. and Hoersch, S. and Horvitz, H.R.
RNA 17 (12): 2201-2211. December 2011

A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in caenorhabditis elegans.
Mansisidor, A.R. and Cecere, G. and Hoersch, S. and Jensen, M.B. and Kawli, T. and Kennedy, L.M. and Chavez, V. and Tan, M.W. and Lieb, J.D. and Grishok, A.
PLoS Genetics 7 (9): e1002299. September 2011

A fraction of MCM 2 proteins remain associated with replication foci during a major part of S phase.
Masata, M. and Juda, P. and Raska, O. and Cardoso, M.C. and Raska, I.
Folia Biologica Prague 57 (1): 3-11. 2011

Chemoresistance in non-small-cell lung cancer: can multidrug resistance markers predict the response of xenograft lung cancer models to chemotherapy?
Merk, J. and Rolff, J. and Dorn, C. and Leschber, G. and Fichtner, I.
European Journal of Cardio-Thoracic Surgery 40 (1): e29-e33. July 2011

Eukaryotic initiation factor 2α phosphorylation is required for B cell maturation and function in mice.
Mielke, N. and Schwarzer, R. and Calkhoven, C.F. and Kaufman, R. and Doerken, B. and Leutz, A. and Jundt, F.
Haematologica 96 (9): 1261-1268. September 2011

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat.
Milde, T. and Kleber, S. and Korshunov, A. and Witt, H. and Hielscher, T. and Koch, P. and Kopp, H.G. and Jugold, M. and Deubzer, H.E. and Oehme, I. and Lodrini, M. and Gröne, H.J. and Benner, A. and Brüstle, O. and Gilbertson, R.J. and von Deimling, A. and Kulozik, A.E. and Pfister, S.M. and Martin-Villalba, A. and Witt, O.
Acta Neuropathologica 122 (5): 637-650. November 2011

S3-Leitlinie "Magenkarzinom" - Diagnostik und Therapie der Adenokarzinome des Magens und oesophagogastralen Uebergangs (AWMF-Regist.-Nr. 032-009-OL) [German S3-Guideline "Diagnosis and Treatment of Esophagogastric Cancer"].
Moehler, M. and Al-Batran, S.E. and Andus, T. and Anthuber, M. and Arends, J. and Arnold, D. and Aust, D. and Baier, P. and Baretton, G. and Bernhardt, J. and Boeing, H. and Boehle, E. and Bokemeyer, C. and Bornschein, J. and Budach, W. and Burmester, E. and Caca, K. and Diemer, W.A. and Dietrich, C.F. and Ebert, M. and Eickhoff, A. and Ell, C. and Fahlke, J. and Feußner, H. and Fietkau, R. and Fischbach, W. and Fleig, W. and Flentje, M. and Gabbert, H.E. and Galle, P.R. and Geissler, M. and Gockel, I. and Graeven, U. and Grenacher, L. and Gross, S. and Hartmann, J.T. and Heike, M. and Heinemann, V. and Herbst, B. and Herrmann, T. and Hoecht, S. and Hofheinz, R.D. and Hoefler, H. and Hoehler, T. and Hoelscher, A.H. and Horneber, M. and Huebner, J. and Izbicki, J.R. and Jakobs, R. and Jenssen, C. and Kanzler, S. and Keller, M. and Kiesslich, R. and Klautke, G. and Körber, J. and Krause, B.J. and Kuhn, C. and Kullmann, F. and Lang, H. and Link, H. and Lordick, F. and Ludwig, K. and Lutz, M. and Mahlberg, R. and Malfertheiner, P. and Merkel, S. and Messmann, H. and Meyer, H.J. and Moenig, S. and Piso, P. and Pistorius, S. and Porschen, R. and Rabenstein, T. and Reichardt, P. and Ridwelski, K. and Roecken, C. and Roetzer, I. and Rohr, P. and Schepp, W. and Schlag, P.M. and Schmid, R.M. and Schmidberger, H. and Schmiegel, W.H. and Schmoll, H.J. and Schuch, G. and Schuhmacher, C. and Schuette, K. and Schwenk, W. and Selgrad, M. and Sendler, A. and Seraphin, J. and Seufferlein, T. and Stahl, M. and Stein, H. and Stoll, C. and Stuschke, M. and Tannapfel, A. and Tholen, R. and Thuss-Patience, P. and Treml, K. and Vanhoefer, U. and Vieth, M. and Vogelsang, H. and Wagner, D. and Wedding, U. and Weimann, A. and Wilke, H. and Wittekind, C.
Zeitschrift fuer Gastroenterologie 49 (4): 461-531. April 2011

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.
Morin, R.D. and Mendez-Lago, M. and Mungall, A.J. and Goya, R. and Mungall, K.L. and Corbett, R.D. and Johnson, N.A. and Severson, T.M. and Chiu, R. and Field, M. and Jackman, S. and Krzywinski, M. and Scott, D.W. and Trinh, D.L. and Tamura-Wells, J. and Li, S. and Firme, M.R. and Rogic, S. and Griffith, M. and Chan, S. and Yakovenko, O. and Meyer, I.M. and Zhao, E.Y. and Smailus, D. and Moksa, M. and Chittaranjan, S. and Rimsza, L. and Brooks-Wilson, A. and Spinelli, J.J. and Ben-Neriah, S. and Meissner, B. and Woolcock, B. and Boyle, M. and McDonald, H. and Tam, A. and Zhao, Y. and Delaney, A. and Zeng, T. and Tse, K. and Butterfield, Y. and Birol, I. and Holt, R. and Schein, J. and Horsman, D.E. and Moore, R. and Jones, S.J.M. and Connors, J.M. and Hirst, M. and Gascoyne, R.D. and Marra, M.A.
Nature 476 (7360): 298-303. 18 August 2011

Structural and thermodynamic characterization of the adrenodoxin-like domain of the electron-transfer protein Etp1 from Schizosaccharomyces pombe.
Mueller, J.J. and Hannemann, F. and Schiffler, B. and Ewen, K.M. and Kappl, R. and Heinemann, U. and Bernhardt, R.
Journal of Inorganic Biochemistry 105 (7): 957-965. July 2011

PAN-modular structure of microneme protein SML-2 from the parasite Sarcocystis muris at 1.95 Å resolution and its complex with 1-thio-β-D-galactose.
Mueller, J.J. and Weiss, M.S. and Heinemann, U.
Acta Crystallographica Section D 67 (Pt 11): 936-944. November 2011

Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.
Mukherjee, N. and Corcoran, D.L. and Nusbaum, J.D. and Reid, D.W. and Georgiev, S. and Hafner, M. and Ascano, M. and Tuschl, T. and Ohler, U. and Keene, J.D.
Molecular Cell 43 (3): 327-339. 5 August 2011

Functional evidence of post-transcriptional regulation by pseudogenes.
Muro, E.M. and Mah, N. and Andrade-Navarro, M.A.
Biochimie 93 (11): 1916-1921. November 2011

The pseudogenes of Mycobacterium leprae reveal the functional relevance of gene order within operons.
Muro, E.M. and Mah, N. and Moreno-Hagelsieb, G. and Andrade-Navarro, M.A.
Nucleic Acids Research 39 (5): 1732-1738. 1 March 2011

Protein kinase C inhibitor Sotrastaurin selectively inhibits the growth of CD79-mutant diffuse large B-cell lymphomas.
Naylor, T.L. and Tang, H. and Ratsch, B.A. and Enns, A. and Loo, A. and Chen, L. and Lenz, P. and Schuler, W. and Doerken, B. and Yao, Y.M. and Warmuth, M. and Lenz, G. and Stegmeier, F.
Cancer Research 71 (7): 2643-2653. 1 April 2011

Luminal CD4 + T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation.
Nemoto, Y. and Kanai, T. and Shinohara, T. and Ito, T. and Nakamura, T. and Okamoto, R. and Tsuchiya, K. and Lipp, M. and Eishi, Y. and Watanabe, M.
Gastroenterology 141 (6): 2130-2139.e11. December 2011

Pathogenesis of non-Hodgkin's lymphoma.
Nogai, H. and Doerken, B. and Lenz, G.
Journal of Clinical Oncology 29 (14): 1803-1811. 10 May 2011

Improving the transport of chemotherapeutic drugs across the blood-brain barrier.
Orthmann, A. and Fichtner, I. and Zeisig, R.
Expert Review of Clinical Pharmacology 4 (4): 477-490. July 2011

First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group.
Pelzer, U. and Arnold, D. and Reitzig, P. and Herrenberger, J. and Korsten, F.W. and Kindler, M. and Stieler, J. and Doerken, B. and Riess, H. and Oettle, H.
Cancer Chemotherapy and Pharmacology 68 (5): 1173-1178. November 2011

Best supportive care (BSC) versus oxaliplatin, folinic acid and 5-fluorouracil (OFF) plus BSC in patients for second-line advanced pancreatic cancer: A phase III-study from the German CONKO-study group.
Pelzer, U. and Schwaner, I. and Stieler, J. and Adler, M. and Seraphin, J. and Doerken, B. and Riess, H. and Oettle, H.
European Journal of Cancer 47 (11): 1676-1681. July 2011

A differential proteome screening system for post-translational modification-dependent transcription factor interactions.
Pless, O. and Kowenz-Leutz, E. and Dittmar, G. and Leutz, A.
Nature Protocols 6 (3): 359-364. February 2011

Breast cancer: early- and late-fluorescence near-infrared imaging with indocyanine green a preliminary study.
Poellinger, A. and Burock, S. and Grosenick, D. and Hagen, A. and Luedemann, L. and Diekmann, F. and Engelken, F. and Macdonald, R. and Rinneberg, H. and Schlag, P.M.
Radiology 258 (2): 409-416. February 2011

Hepatic arterial infusion in the treatment of liver metastases with PEG liposomes in combination with degradable starch microspheres (DSM) increases tumor 5-FU concentration. An animal study in CC-531 liver tumor-bearing rats.
Pohlen, U. and Reszka, R. and Buhr, H.J. and Berger, G.
Anticancer Research 31 (1): 147-152. January 2011

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic, J. and Li, L.P. and Kloetzel, P.M. and Leisegang, M. and Uckert, W. and Blankenstein, T.
Blood 118 (4): 946-954. 28 July 2011

Automatic annotation of spatial expression patterns via sparse Bayesian factor models.
Pruteanu-Malinici, I. and Mace, D.L. and Ohler, U.
PLoS Computational Biology 7 (7): e1002098. July 2011

Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level.
Rach, E.A. and Winter, D.R. and Benjamin, A.M. and Corcoran, D.L. and Ni, T. and Zhu, J. and Ohler, U.
PLoS Genetics 7 (1): e1001274. 13 January 2011

The use of microarray technologies in mantle cell lymphoma.
Ratsch, B.A. and Grau, M. and Doerken, B. and Lenz, P. and Lenz, G.
Seminars in Hematology 48 (3): 166-171. July 2011

E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
Redmer, T. and Diecke, S. and Grigoryan, T. and Quiroga-Negreira, A. and Birchmeier, W. and Besser, D.
EMBO Reports 12 (7): 720-726. 1 July 2011

Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Rehm, A. and Mensen, A. and Schradi, K. and Gerlach, K. and Wittstock, S. and Winter, S. and Buechner, G. and Doerken, B. and Lipp, M. and Hoepken, U.E.
Blood 118 (4): 1020-1033. 28 July 2011

Non-cell-autonomous tumor suppression: oncogene-provoked apoptosis promotes tumor cell senescence via stromal crosstalk.
Reimann, M. and Schmitt, C.A. and Lee, S.
Journal of Molecular Medicine 89 (9): 869-875. September 2011

S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells.
Sack, U. and Walther, W. and Scudiero, D. and Selby, M. and Aumann, J. and Lemos, C. and Fichtner, I. and Schlag, P.M. and Shoemaker, R.H. and Stein, U.
Molecular Biology of the Cell 22 (18): 3344-3354. September 2011

Novel effect of antihelminthic niclosamide on S100A4-mediated metastatic progression in colon cancer.
Sack, U. and Walther, W. and Scudiero, D. and Selby, M. and Kobelt, D. and Lemm, M. and Fichtner, I. and Schlag, P.M. and Shoemaker, R.H. and Stein, U.
Journal of the National Cancer Institute 103 (13): 1018-1036. 6 July 2011

Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain.
Saupe, J. and Roske, Y. and Schillinger, C. and Kamdem, N. and Radetzki, S. and Diehl, A. and Oschkinat, H. and Krause, G. and Heinemann, U. and Rademann, J.
ChemMedChem 6 (8): 1411-1422. 1 August 2011

Characterization of FarR as a highly specialized, growth phase-dependent transcriptional regulator in Neisseria meningitidis.
Schielke, S. and Spatz, C. and Schwarz, R.F. and Joseph, B. and Schoen, C. and Schulz, S.M. and Hubert, K. and Frosch, M. and Schubert-Unkmeir, A. and Kurzai, O.
International Journal of Medical Microbiology 301 (4): 325-333. April 2011

Development of a BAC vector for integration-independent and tight regulation of transgenes in rodents via the Tet system.
Schoenig, K. and Kentner, D. and Gossen, M. and Baldinger, T. and Miao, J. and Welzel, K. and Vente, A. and Bartsch, D. and Bujard, H.
Transgenic Research 20 (3): 709-720. June 2011

The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation.
Schuetz, A. and Nana, D. and Rose, C. and Zocher, G. and Milanovic, M. and Koenigsmann, J. and Blasig, R. and Heinemann, U. and Carstanjen, D.
Cellular and Molecular Life Sciences 68 (18): 3121-3131. September 2011

Sphingosine-1-phospate receptor 4 (S1P4) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model.
Schulze, T. and Golfier, S. and Tabeling, C. and Raebel, K. and Graeler, M.H. and Witzenrath, M. and Lipp, M.
FASEB Journal 25 (11): 4024-4036. November 2011

Notch and NF-κB signaling pathways in the biology of classical Hodgkin lymphoma.
Schwarzer, R. and Jundt, F.
Current Molecular Medicine 11 (3): 236-245. April 2011

GTP-dependent scaffold formation in the GTPase of Immunity Associated Protein family.
Schwefel, D. and Daumke, O.
Small GTPases 2 (1): 27-30. January 2011

Transmitter- and hormone-activated Ca(2+) responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca(2+) sensor.
Seifert, S. and Pannell, M. and Uckert, W. and Faerber, K. and Kettenmann, H.
Cell Calcium 49 (6): 365-375. June 2011

Recognition of 2'-O-methylated 3'-end of piRNA by the PAZ domain of a piwi protein.
Simon, B. and Kirkpatrick, J.P. and Eckhardt, S. and Reuter, M. and Rocha, E.A. and Andrade-Navarro, M.A. and Sehr, P. and Pillai, R.S. and Carlomagno, T.
Structure 19 (2): 172-180. 9 February 2011

Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis.
Stein, U. and Arlt, F. and Smith, J. and Sack, U. and Herrmann, P. and Walther, W. and Lemm, M. and Fichtner, I. and Shoemaker, R.H. and Schlag, P.M.
Neoplasia 13 (2): 131-144. February 2011

Diagnostic and prognostic value of metastasis inducer S100A4 transcripts in plasma of colon, rectal, and gastric cancer patients.
Stein, U. and Burock, S. and Herrmann, P. and Wendler, I. and Niederstrasser, M. and Wernecke, K.D. and Schlag, P.M.
Journal of Molecular Diagnostics 13 (2): 189-198. March 2011

Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A. and Moebs, M. and Ullmann, R. and Koechert, K. and Kreher, S. and Lamprecht, B. and Anagnostopoulos, I. and Hummel, M. and Richter, J. and Beyer, M. and Janz, M. and Klemke, C.D. and Stein, H. and Doerken, B. and Sterry, W. and Schrock, E. and Mathas, S. and Assaf, C.
Journal of Experimental Medicine 208 (8): 1585-1593. 1 August 2011

Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer.
Tan, W.L. and Bhattacharya, B. and Loh, M. and Balasubramanian, I. and Akram, M. and Dong, D. and Wong, L. and Thakkar, B. and Salto-Tellez, M. and Soo, R.A. and Fichtner, I. and Iacopetta, B. and Soong, R.
Cancer Biology & Therapy 11 (6): 599-608. 15 March 2011

Discovery of a novel tumour metastasis-promoting gene, NVM-1.
Thiele, W. and Novac, N. and Mink, S. and Schreiber, C. and Plaumann, D. and Fritzmann, J. and Cremers, N. and Rothley, M. and Schwager, C. and Regiert, T. and Huber, P.E. and Stein, U. and Schlag, P. and Moll, J. and Abdollahi, A. and Sleeman, J.P.
Journal of Pathology 225 (1): 96-105. September 2011

Different roles of the human Orc6 protein in the replication initiation process.
Thomae, A.W. and Baltin, J. and Pich, D. and Deutsch, M.J. and Ravasz, M. and Zeller, K. and Gossen, M. and Hammerschmidt, W. and Schepers, A.
Cellular and Molecular Life Sciences 68 (22): 3741-3756. November 2011

BAY 43-9006/Sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines.
Ullrich, K. and Wurster, K.D. and Lamprecht, B. and Koechert, K. and Engert, A. and Doerken, B. and Janz, M. and Mathas, S.
British Journal of Haematology 155 (3): 398-402. November 2011

Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth.
Waaler, J. and Machon, O. and von Kries, J.P. and Wilson, S.R. and Lundenes, E. and Wedlich, D. and Gradl, D. and Paulsen, J.E. and Machonova, O. and Dembinski, J.L. and Dinh, H. and Krauss, S.
Cancer Research 71 (1): 197-205. 1 January 2011

Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload.
Waehre, A. and Halvorsen, B. and Yndestad, A. and Husberg, C. and Sjaastad, I. and Nygard, S. and Dahl, C.P. and Ahmed, M.S. and Finsen, A.V. and Reims, H. and Louch, W.E. and Hilfiker-Kleiner, D. and Vinge, L.E. and Roald, B. and Attramadal, H. and Lipp, M. and Gullestad, L. and Aukrust, P. and Christensen, G.
PLoS ONE 6 (4): e18668. 18 April 2011

Perfluorocarbon particle size influences magnetic resonance signal and immunological properties of dendritic cells.
Waiczies, H. and Lepore, S. and Janitzek, N. and Hagen, U. and Seifert, F. and Ittermann, B. and Purfuerst, B. and Pezzutto, A. and Paul, F. and Niendorf, T. and Waiczies, S.
PLoS ONE 6 (7): e21981. 19 July 2011

Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study.
Westermann, J. and Floercken, A. and Willimsky, G. and van Lessen, A. and Kopp, J. and Takvorian, A. and Joehrens, K. and Lukowsky, A. and Schoenemann, C. and Sawitzki, B. and Pohla, H. and Frank, R. and Doerken, B. and Schendel, D.J. and Blankenstein, T. and Pezzutto, A.
Gene Therapy 18 (4): 354-363. April 2011

Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development.
Wilke, S. and Groebe, L. and Maffenbeier, V. and Jaeger, V. and Gossen, M. and Josewski, J. and Duda, A. and Polle, L. and Owens, R.J. and Wirth, D. and Heinz, D.W. and van den Heuvel, J. and Buessow, K.
PLoS ONE 6 (12): e27829. December 2011

The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney.
Willecke, R. and Heuberger, J. and Grossmann, K. and Michos, O. and Schmidt-Ott, K. and Walentin, K. and Costantini, F. and Birchmeier, W.
Developmental Biology 360 (2): 310-307. 15 December 2011

Molecular mode of action and role of TP53 in the sensitivity to the novel epothilone sagopilone (ZK-EPO) in A549 non-small cell lung cancer cells.
Winsel, S. and Sommer, A. and Eschenbrenner, J. and Mittelstaedt, K. and Klar, U. and Hammer, S. and Hoffmann, J.
PLoS ONE 6 (4): e19273. 29 April 2011

Manifestation of spontaneous and early autoimmune gastritis in CCR7-deficient mice.
Winter, S. and Rehm, A. and Wichner, K. and Scheel, T. and Batra, A. and Siegmund, B. and Berek, C. and Lipp, M. and Hoepken, U.E.
American Journal of Pathology 179 (2): 754-765. August 2011

Intrahepatically transplanted human cord blood cells reduce SW480 tumor growth in the presence of bispecific EpCAM/CD3 antibody.
Wulf-Goldenberg, A. and Eckert, K. and Fichtner, I.
Cytotherapy 13 (1): 108-113. January 2011

Post-transplantation chronic myeloid leukemia.
le Coutre, P. and Schwarz, M. and Daniel, P. and Doerken, B.
Clinical Advances in Hematology & Oncology 9 (8): 627-629. August 2011

Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway.
von Haefen, C. and Wendt, J. and Semini, G. and Sifringer, M. and Belka, C. and Radetzki, S. and Reutter, W. and Daniel, P.T. and Danker, K.
Apoptosis 16 (6): 636-651. March 2011

2010

Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel.
Adema, A.D. and Laan, A.C. and Myhren, F. and Fichtner, I. and Verheul, H.M. and Sandvold, M.L. and Peters, G.J.
International Journal of Oncology 36 (1): 285-294. 1 January 2010

An alignment-free method to identify candidate orthologous enhancers in multiple Drosophila genomes.
Arunachalam, M. and Jayasurya, K. and Tomancak, P. and Ohler, U.
Bioinformatics 26 (17): 2109-2115. 1 September 2010

Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.
Ash, M.R. and Faelber, K. and Kosslick, D. and Albert, G.I. and Roske, Y. and Kofler, M. and Schuemann, M. and Krause, E. and Freund, C.
Structure 18 (8): 944-954. 11 August 2010

Enhanced resolution of sedimentation coefficient distribution profiles by extrapolation to infinite time.
Behlke, J. and Ristau, O.
European Biophysics Journal 39 (3): 449-455. February 2010

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.
Bendle, G.M. and Linnemann, C. and Hooijkaas, A.I. and Bies, L. and de Witte, M.A. and Jorritsma, A. and Kaiser, A.D.M. and Pouw, N. and Debets, R. and Kieback, E. and Uckert, W. and Song, J.Y. and Haanen, J.B.A.G. and Schumacher, T.N.M.
Nature Medicine 16 (5): 565-570, 1p following 570. May 2010

Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition.
Blattmann, C. and Oertel, S. and Ehemann, V. and Thiemann, M. and Huber, P.E. and Bischof, M. and Witt, O. and Deubzer, H.E. and Kulozik, A.E. and Debus, J. and Weber, K.J.
International Journal of Radiation Oncology, Biology, Physics 78 (1): 237-245. 1 September 2010

Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme.
Boehm, K. and Herter, T. and Mueller, J.J. and Borriss, R. and Heinemann, U.
FEBS Journal 277 (5): 1284-1296. March 2010

Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy.
Brueckner, B. and Rius, M. and Rivera Markelova, M. and Fichtner, I. and Hals, P.A. and Sandvold, M.L. and Lyko, F.
Molecular Cancer Therapeutics 9 (5): 1256-1264. May 2010

Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.
Buchberger, A. and Bukau, B. and Sommer, T.
Molecular Cell 40 (2): 238-252. 22 October 2010

Phase I trial of an allogeneic gene-modified tumor cell vaccine (RCC-26/CD80/IL-2) in patients with metastatic renal cell carcinoma.
Buchner, A. and Pohla, H. and Willimsky, G. and Frankenberger, B. and Frank, R. and Baur-Melnyk, A. and Siebels, M. and Stief, C.G. and Hofstetter, A. and Kopp, J. and Pezzutto, A. and Blankenstein, T. and Oberneder, R. and Schendel, D.J.
Human Gene Therapy 21 (3): 285-297. March 2010

Do CARs need a driver's license? Adoptive cell therapy with chimeric antigen receptor-redirected T cells caused serious adverse events.
Buening, H. and Uckert, W. and Cichutek, K. and Hawkins, R.E. and Abken, H.
Human Gene Therapy 21 (9): 1039-1042. September 2010

Integration der Hyperthermie in chirurgisch-onkologische Techniken [Integration of hyperthermia into surgical oncological techniques].
Burock, S. and Schlag, P.M.
Onkologe 16 (11): 1079-1085. November 2010

In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance.
Buschow, C. and Charo, J. and Anders, K. and Loddenkemper, C. and Jukica, A. and Alsamah, W. and Perez, C. and Willimsky, G. and Blankenstein, T.
Journal of Immunology 184 (6): 2930-2938. 15 March 2010

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma.
Calado, D.P. and Zhang, B. and Srinivasan, L. and Sasaki, Y. and Seagal, J. and Unitt, C. and Rodig, S. and Kutok, J. and Tarakhovsky, A. and Schmidt-Supprian, M. and Rajewsky, K.
Cancer Cell 18 (6): 580-589. 14 December 2010

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R. and Sternjak, A. and Wend, P. and Momma, S. and Campos, B. and Herrmann, I.M. and Graf, D. and Mitsiadis, T. and Herold-Mende, C. and Besser, D. and Synowitz, M. and Kettenmann, H. and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

The immune response to sporadic colorectal cancer in a novel mouse model.
Czeh, M. and Loddenkemper, C. and Shalapour, S. and Schoen, C. and Robine, S. and Goldscheid, E. and Stein, H. and Schueler, T. and Willimsky, G. and Blankenstein, T.
Oncogene 29 (50): 6591-6602. 16 December 2010

Authors' reply: Treatment of oesophageal anastomotic leaks by temporary stenting with self-expanding plastic stents (Br J Surg 2009; 96: 887-891).
Dai, Y.Y. and Gretschel, S. and Dudeck, O. and Rau, B. and Schlag, P.M. and Huenerbein, M.
British Journal of Surgery 97 (2): 294-295. February 2010

Generation of an antibody against the protein phosphatase 1 inhibitor KEPI and characterization of the epitope.
Daskalow, K. and Boisguerin, P. and Jandrig, B. and Van Landeghem, F.K. and Volkmer, R. and Micheel, B. and Schenk, J.A.
Anticancer Research 30 (5): 1573-1578. May 2010

Structure of the MxA stalk elucidates the assembly of ring-like units of an antiviral module.
Daumke, O. and Gao, S. and von der Malsburg, A. and Haller, O. and Kochs, G.
Small GTPases 1 (1): 62-64. July 2010

Suspension medium influences interaction of mesenchymal stromal cells with endothelium and pulmonary toxicity after transplantation in mice.
Deak, E. and Ruester, B. and Keller, L. and Eckert, K. and Fichtner, I. and Seifried, E. and Henschler, R.
Cytotherapy 12 (2): 260-264. April 2010

Small-molecule inhibition of APT1 affects Ras localization and signaling.
Dekker, F.J. and Rocks, O. and Vartak, N. and Menninger, S. and Hedberg, C. and Balamurugan, R. and Wetzel, S. and Renner, S. and Gerauer, M. and Schoelermann, B. and Rusch, M. and Kramer, J.W. and Rauh, D. and Coates, G.W. and Brunsveld, L. and Bastiaens, P.I. and Waldmann, H.
Nature Chemical Biology 6 (6): 449-456. June 2010

Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial.
Eich, H.T. and Diehl, V. and Goergens, H. and Pabst, T. and Markova, J. and Debus, J. and Ho, A. and Doerken, B. and Rank, A. and Grosu, A.L. and Wiegel, T. and Karstens, J.H. and Greil, R. and Willich, N. and Schmidberger, H. and Doehner, H. and Borchmann, P. and Mueller-Hermelink, H.K. and Mueller, R.P. and Engert, A.
Journal of Clinical Oncology 28 (27): 4199-4206. 20 September 2010

Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma.
Engert, A. and Pluetschow, A. and Eich, H.T. and Lohri, A. and Doerken, B. and Borchmann, P. and Berger, B. and Greil, R. and Willborn, K.C. and Wilhelm, M. and Debus, J. and Eble, M.J. and Soekler, M. and Ho, A. and Rank, A. and Ganser, A. and Truemper, L. and Bokemeyer, C. and Kirchner, H. and Schubert, J. and Kral, Z. and Fuchs, M. and Mueller-Hermelink, H.K. and Mueller, R.P. and Diehl, V.
New England Journal of Medicine 363 (7): 640-652. 12 August 2010

Antitumor activity of vanadocene Y and its selenocyanate derivative in xenografted CAKI-1 tumors in mice.
Fichtner, I. and Claffey, J. and Deally, A. and Gleeson, B. and Hogan, M. and Rivera Markelova, M. and Mueller-Bunz, H. and Weber, H. and Tacke, M.
Journal of Organometallic Chemistry 695 (8): 1175-1181. 15 April 2010

Therapeutic potential of CAMPATH-1H in skeletal tumours.
Fritsche-Guenther, R. and Gruetzkau, A. and Noske, A. and Melcher, I. and Schaser, K.D. and Schlag, P.M. and Kasper, H.U. and Krenn, V. and Sers, C.
Histopathology 57 (6): 851-861. December 2010

De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway.
Fritsche-Guenther, R. and Noske, A. and Ungethuem, U. and Kuban, R.J. and Schlag, P.M. and Tunn, P.U. and Karle, J. and Krenn, V. and Dietel, M. and Sers, C.
Histopathology 57 (6): 836-850. December 2010

Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao, S. and von der Malsburg, A. and Paeschke, S. and Behlke, J. and Haller, O. and Kochs, G. and Daumke, O.
Nature 465 (7297): 502-506. 27 May 2010

Evidence-ranked motif identification.
Georgiev, S. and Boyle, A.P. and Jayasurya, K. and Ding, X. and Mukherjee, S. and Ohler, U.
Genome Biology 11 (2): R19. 15 February 2010

Interwoven four-compartment capillary membrane technology for three-dimensional perfusion with decentralized mass exchange to scale up embryonic stem cell culture.
Gerlach, J. and Luebberstedt, M. and Edsbagge, J. and Ring, A. and Hout, M. and Baun, M. and Rossberg, I. and Knoespel, F. and Peters, G. and Eckert, K. and Wulf-Goldenberg, A. and Bjoerquist, P. and Stachelscheid, H. and Urbaniak, T. and Schatten, G. and Miki, T. and Schmelzer, E. and Zeilinger, K.
Cells Tissues Organs 192 (1): 39-49. June 2010

Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.
Gillissen, B. and Wendt, J. and Richter, A. and Richter, A. and Mueer, A. and Overkamp, T. and Gebhardt, N. and Preissner, R. and Belka, C. and Doerken, B. and Daniel, P.T.
Journal of Cell Biology 188 (6): 851-862. 22 March 2010

Practice and effectiveness of outpatient psycho-oncological counseling for cancer patients.
Goerling, U. and Tagmat, D. and Muffler, E. and Schramm, N. and Wernecke, K.D. and Schlag, P.M.
Journal of Cancer 1 : 112-119. 23 August 2010

Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4.
Golfier, S. and Kondo, S. and Schulze, T. and Takeuchi, T. and Vassileva, G. and Achtman, A.H. and Graeler, M.H. and Abbondanzo, S.J. and Wiekowski, M. and Kremmer, E. and Endo, Y. and Lira, S.A. and Bacon, K.B. and Lipp, M.
FASEB Journal 24 (12): 4701-4710. December 2010

INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model.
Graeser, R. and Esser, N. and Unger, H. and Fichtner, I. and Zhu, A. and Unger, C. and Kratz, F.
Investigational New Drugs 28 (1): 14-19. February 2010

Current status of sentinel lymph node biopsy in adenocarcinoma of the distal esophagus, gastric cardia, and proximal stomach.
Gretschel, S. and Schlag, P.M.
Recent Results in Cancer Research 182 : 107-114. 2010

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S. and Rosario, M. and Birchmeier, C. and Birchmeier, W.
Advances in Cancer Research 106 : 53-89. 2010

Ectopic expression of E2F1 stimulates beta cell proliferation and function.
Grouwels, G. and Cai, Y. and Hoebeke, I. and Leuckx, G. and Heremans, Y. and Ziebold, U. and Stange, G. and Chintinne, M. and Ling, Z. and Pipeleers, D. and Heimberg, H. and Van de Casteele, M.
Diabetes 59 (6): 1435-1444. June 2010

Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Guenther, S. and Schlundt, A. and Sticht, J. and Roske, Y. and Heinemann, U. and Wiesmueller, K.H. and Jung, G. and Falk, K. and Roetzschke, O. and Freund, C.
Proceedings of the National Academy of Sciences of the United States of America 107 (51): 22219-22224. 21 December 2010

Human peripheral blood and bone marrow Epstein-Barr virus-specific T-cell repertoire in latent infection reveals distinct memory T-cell subsets.
Guerreiro, M. and Na, I.K. and Letsch, A. and Haase, D. and Bauer, S. and Meisel, C. and Roemhild, A. and Reinke, P. and Volk, H.D. and Scheibenbogen, C.
European Journal of Immunology 40 (6): 1566-1576. June 2010

Dynamin-like MxA GTPase: Structural insights into oligomerization and implications for antiviral activity.
Haller, O. and Gao, S. and von der Malsburg, A. and Daumke, O. and Kochs, G.
Journal of Biological Chemistry 285 (37): 28419-28424. 10 September 2010

Comparative profiling of the novel epothilone, sagopilone, in xenografts derived from primary non-small cell lung cancer.
Hammer, S. and Sommer, A. and Fichtner, I. and Becker, M. and Rolff, J. and Merk, J. and Klar, U. and Hoffmann, J.
Clinical Cancer Research 16 (5): 1452-1465. 1 March 2010

Comparison of the effect of orally administered soluble β-(1-3),(1-6)-D-glucan and of G-CSF on the recovery of murine hematopoiesis.
Harnack, U. and Eckert, K. and Fichtner, I. and Pecher, G.
In Vivo 24 (1): 59-63. January 2010

Cellular senescence predicts treatment outcome in metastasised colorectal cancer.
Haugstetter, A.M. and Loddenkemper, C. and Lenze, D. and Groene, J. and Standfuss, C. and Petersen, I. and Doerken, B. and Schmitt, C.A.
British Journal of Cancer 103 (4): 505-509. 10 August 2010

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation.
Haurie, V. and Durrieu-Gaillard, S. and Dumay-Odelot, H. and Da Silva, D. and Rey, C. and Prochazkova, M. and Roeder, R.G. and Besser, D. and Teichmann, M.
Proceedings of the National Academy of Sciences of the United States of America 107 (9): 4176-4181. 2 March 2010

Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT.
Hayashida, N. and Fujimoto, M. and Tan, K. and Prakasam, R. and Shinkawa, T. and Li, L. and Ichikawa, H. and Takii, R. and Nakai, A.
EMBO Journal 29 (20): 3459-3469. 20 October 2010

Structure of a classical MHC class I molecule that binds "non-classical" ligands.
Hee, C.S. and Gao, S. and Loll, B. and Miller, M.M. and Uchanska-Ziegler, B. and Daumke, O. and Ziegler, A.
PLoS Biology 8 (12): e1000557. 7 December 2010

Systematic genetic dissection of p14(ARF)-mediated mitochondrial cell death signaling reveals a key role for p21(CDKN1) and the BH3-only protein Puma/bbc3.
Hemmati, P.G. and Mueer, A. and Gillissen, B. and Overkamp, T. and Milojkovic, A. and Wendt, J. and Doerken, B. and Daniel, P.T.
Journal of Molecular Medicine 88 (6): 609-622. June 2010

Reduced intensity conditioning prior to allogeneic stem cell transplantation in first complete remission is effective in patients with acute myeloid leukemia and an intermediate-risk karyotype.
Hemmati, P.G. and Terwey, T.H. and Massenkeil, G. and le Coutre, P. and Vuong, L.G. and Neuburger, S. and Doerken, B. and Arnold, R.
International Journal of Hematology 91 (3): 436-445. April 2010

Interplay of cadherin-mediated cell adhesion and canonical wnt signaling.
Heuberger, J. and Birchmeier, W.
Cold Spring Harbor Perspectives in Biology 2 (2): a002915. February 2010

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz, M. and Stilmann, M. and Coel Arslan, S. and Khanna, K.K. and Dittmar, G. and Scheidereit, C.
Molecular Cell 40 (1): 63-74. 8 October 2010

CCR7 regulates lymphocyte egress and recirculation through body cavities.
Hoepken, U.E. and Winter, S. and Achtman, A.H. and Krueger, K. and Lipp, M.
Journal of Leukocyte Biology 87 (4): 671-682. April 2010

The winged-helix transcription factor JUMU regulates development, nucleolus morphology and function, and chromatin organization of Drosophila melanogaster.
Hofmann, A. and Bruenner, M. and Schwendemann, A. and Stroedicke, M. and Karberg, S. and Klebes, A. and Saumweber, H. and Korge, G.
Chromosome Research 18 (3): 307-324. April 2010

Pankreaskarzinom - auf der therapeutischen Wartebank [Pancreatic cancer - on the therapeutic waiting bench].
Hopt, U. and Schlag, P.M.
Onkologe 16 (6): 555-556. June 2010

In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy.
Ishimaru, N. and Nitta, T. and Arakaki, R. and Yamada, A. and Lipp, M. and Takahama, Y. and Hayashi, Y.
PLoS ONE 5 (1): e8588. 5 January 2010

Die Bedeutung molekulargenetischer Veraenderungen fuer eine verbesserte Frueherkennung und Risikoabschaetzung beim Brustkrebs.
Jandrig, B. and Scherneck, S.
In: Onkologie : Grundlagen - Diagnostik - Therapie - Entwicklungen. ecomed Medizin, 1-32. ISBN 978-3-609-76300-2 2010

Gallengangskarzinom - Fortschritte und Grenzverschiebungen[Cholangiocarcinoma - Progress and shifting boundaries].
Jonas, S. and Schlag, P.M.
Onkologe 16 (9): 840. September 2010

Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence.
Joseph, B. and Schneiker-Bekel, S. and Schramm-Glueck, A. and Blom, J. and Claus, H. and Linke, B. and Schwarz, R.F. and Becker, A. and Goesmann, A. and Frosch, M. and Schoen, C.
Journal of Bacteriology 192 (20): 5363-5377. October 2010

Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Juerchott, K. and Kuban, R.J. and Krech, T. and Bluethgen, N. and Stein, U. and Walther, W. and Friese, C. and Kielbasa, S.M. and Ungethuem, U. and Lund, P. and Knoesel, T. and Kemmner, W. and Morkel, M. and Fritzmann, J. and Schlag, P.M. and Birchmeier, W. and Krueger, T. and Sperling, S. and Sers, C. and Royer, H.D. and Herzel, H. and Schaefer, R.
PLoS Genetics 6 (12): e1001231. 2 December 2010

Evidence for a broad transition-state ensemble in calmodulin folding from single-molecule force spectroscopy.
Junker, J.P. and Rief, M.
Angewandte Chemie International Edition in English 49 (19): 3306-3309. 26 April 2010

Gene expression divergence recapitulates the developmental hourglass model.
Kalinka, A.T. and Varga, K.M. and Gerrard, D.T. and Preibisch, S. and Corcoran, D.L. and Jarrells, J. and Ohler, U. and Bergman, C.M. and Tomancak, P.
Nature 468 (7325): 811-814. 9 December 2010

Enhanced T cell receptor gene therapy for cancer.
Kieback, E. and Uckert, W.
Expert Opinion on Biological Therapy 10 (5): 749-762. May 2010

Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D. and Schwarz, M. and Nogai, H. and Grille, P. and Westermann, J. and Ploeckinger, U. and Braun, D. and Schweizer, U. and Arnold, R. and Doerken, B. and le Coutre, P.
Thyroid 20 (11): 1209-1214. 9 November 2010

Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia.
Kim, T.D. and Tuerkmen, S. and Schwarz, M. and Koca, G. and Nogai, H. and Bommer, C. and Doerken, B. and Daniel, P. and le Coutre, P.
Haematologica 95 (4): 582-588. April 2010

Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: biphasic heat induction of cytosine deaminase suicide gene expression.
Kobelt, D. and Aumann, J. and Fichtner, I. and Stein, U. and Schlag, P.M. and Walther, W.
Molecular Biotechnology 46 (2): 197-205. October 2010

The ITS2 Database III-sequences and structures for phylogeny.
Koetschan, C. and Foerster, F. and Keller, A. and Schleicher, T. and Ruderisch, B. and Schwarz, R. and Mueller, T. and Wolf, M. and Schultz, J.
Nucleic Acids Research 38 (Suppl 1): D275-D279. January 2010

Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.
Kowenz-Leutz, E. and Pless, O. and Dittmar, G. and Knoblich, M. and Leutz, A.
EMBO Journal 29 (6): 1105-1115. 17 March 2010

Regulation of microRNA expression and abundance during lymphopoiesis.
Kuchen, S. and Resch, W. and Yamane, A. and Kuo, N. and Li, Z. and Chakraborty, T. and Wei, L. and Laurence, A. and Yasuda, T. and Peng, S. and Hu-Li, J. and Lu, K. and Dubois, W. and Kitamura, Y. and Charles, N. and Sun, H.W. and Muljo, S. and Schwartzberg, P.L. and Paul, W.E. and O'Shea, J. and Rajewsky, K. and Casellas, R.
Immunity 32 (6): 828-839. 25 June 2010

Characterization of the self-palmitoylation activity of the transport protein particle component Bet3.
Kuemmel, D. and Walter, J. and Heck, M. and Heinemann, U. and Veit, M.
Cellular and Molecular Life Sciences 67 (15): 2653-2664. August 2010

Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
Kumpf, O. and Giamarellos-Bourboulis, E.J. and Koch, A. and Hamann, L. and Mouktaroudi, M. and Oh, D.Y. and Latz, E. and Lorenz, E. and Schwartz, D.A. and Ferwerda, B. and Routsi, C. and Skalioti, C. and Kullberg, B.J. and van der Meer, J.W. and Schlag, P.M. and Netea, M.G. and Zacharowski, K. and Schumann, R.R.
Critical Care 14 (3): R103. 3 June 2010

Amperometric immunosensor for carcinoembryonic antigen in colon cancer samples based on monolayers of dendritic bipodal scaffolds.
Laboria, N. and Fragoso, A. and Kemmner, W. and Latta, D. and Nilsson, O. and Luz Botero, M. and Drese, K. and O'Sullivan, C.K.
Analytical Chemistry 82 (5): 1712-1719. 1 March 2010

Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells.
Lacroix, J. and Leuchs, B. and Li, J. and Hristov, G. and Deubzer, H.E. and Kulozik, A.E. and Rommelaere, J. and Schlehofer, J.R. and Witt, O.
International Journal of Cancer 127 (5): 1230-1239. 1 September 2010

Efficient algorithms for training the parameters of hidden Markov models using stochastic expectation maximization (EM) training and Viterbi training.
Lam, T.Y. and Meyer, I.M.
Algorithms for Molecular Biology 5 : 38. 9 December 2010

Repeat-element driven activation of proto-oncogenes in human malignancies.
Lamprecht, B. and Bonifer, C. and Mathas, S.
Cell Cycle 9 (21): 4276-4281. November 2010

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B. and Walter, K. and Kreher, S. and Kumar, R. and Hummel, M. and Lenze, D. and Koechert, K. and Bouhlel, M.A. and Richter, J. and Soler, E. and Stadhouders, R. and Joehrens, K. and Wurster, K.D. and Callen, D.F. and Harte, M.F. and Giefing, M. and Barlow, R. and Stein, H. and Anagnostopoulos, I. and Janz, M. and Cockerill, P.N. and Siebert, R. and Doerken, B. and Bonifer, C. and Mathas, S.
Nature Medicine 16 (5): 571-579, 1p following 579. May 2010

A MAS NMR study of the bacterial ABC transporter ArtMP.
Lange, V. and Becker-Baldus, J. and Kunert, B. and van Rossum, B.J. and Casagrande, F. and Engel, A. and Roske, Y. and Scheffel, F.M. and Schneider, E. and Oschkinat, H.
Chembiochem 11 (4): 547-555. 1 March 2010

Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1.
Lausen, J. and Pless, O. and Leonard, F. and Kuvardina-Bolling, O.N. and Koch, B. and Leutz, A.
Journal of Biological Chemistry 285 (8): 5338-5346. 19 February 2010

T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy.
Leisegang, M. and Turqueti-Neves, A. and Engels, B. and Blankenstein, T. and Schendel, D.J. and Uckert, W. and Noessner, E.
Clinical Cancer Research 16 (8): 2333-2343. 15 April 2010

MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors.
Leisegang, M. and Wilde, S. and Spranger, S. and Milosevic, S. and Frankenberger, B. and Uckert, W. and Schendel, D.J.
Journal of Clinical Investigation 120 (11): 3869-3877. 1 November 2010

Transgenic mice with a diverse human T cell antigen receptor repertoire.
Li, L.P. and Lampert, J.C. and Chen, X. and Leitao, C. and Popovic, J. and Mueller, W. and Blankenstein, T.
Nature Medicine 16 (9): 1029-1034. September 2010

Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
Li, M. and Jung, A. and Ganswindt, U. and Marini, P. and Friedl, A. and Daniel, P.T. and Lauber, K. and Jendrossek, V. and Belka, C.
Biochemical Pharmacology 79 (2): 122-129. 15 January 2010

A single TCRα-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire.
Liang, X. and Weigand, L.U. and Schuster, I.G. and Eppinger, E. and van der Griendt, J.C. and Schub, A. and Leisegang, M. and Sommermeyer, D. and Anderl, F. and Han, Y. and Ellwart, J. and Moosmann, A. and Busch, D.H. and Uckert, W. and Peschel, C. and Krackhardt, A.M.
Journal of Immunology 184 (3): 1617-1629. 1 February 2010

Improved Tet-responsive promoters with minimized background expression.
Loew, R. and Heinz, N. and Hampf, M. and Bujard, H. and Gossen, M.
BMC Biotechnology 10 (1): 81. 24 November 2010

Regulation of Ras localization by acylation enables a mode of intracellular signal propagation.
Lorentzen, A. and Kinkhabwala, A. and Rocks, O. and Vartak, N. and Bastiaens, P.I.
Science Signaling 3 (140): ra68. 21 September 2010

Extraction and comparison of gene expression patterns from 2D RNA in situ hybridization images.
Mace, D.L. and Varnado, N. and Zhang, W. and Frise, E. and Ohler, U.
Bioinformatics 26 (6): 761-769. 15 March 2010

Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs.
Majoros, W.H. and Ohler, U.
PLoS Computational Biology 6 (12): e1001037. 16 December 2010

SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma.
Mardin, W.A. and Petrov, K.O. and Enns, A. and Senninger, N. and Haier, J. and Mees, S.T.
BMC Cancer 10 : 549. 12 October 2010

Cellular pharmacology of the anti-hepatitis B virus agent beta-L-2',3'-didehydro-2',3'-dideoxy-N4-hydroxycytidine: relevance for activation in HepG2 cells.
Matthes, E. and Buenger, H.
Antimicrobial Agents and Chemotherapy 54 (1): 341-345. 16 January 2010

ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum.
Mehnert, M. and Sommer, T. and Jarosch, E.
BioEssays 32 (10): 905-913. October 2010

Interleukin-9 (IL-9) and NPM-ALK each generate mast cell hyperplasia as single 'hit' and cooperate in producing a mastocytosis-like disease in mice.
Merz, H. and Kaehler, C. and Hoefig, K.P. and Branke, B. and Uckert, W. and Nadrowitz, R. and Cerny-Reiterer, S. and Herrmann, H. and Feller, A.C. and Valent, P.
Oncotarget 1 (2): 104-119. 7 June 2010

Targeting the epidermal growth factor receptor (HER) family by T cell receptor gene-modified T lymphocytes.
Meyerhuber, P. and Conrad, H. and Staerck, L. and Leisegang, M. and Busch, D.H. and Uckert, W. and Bernhard, H.
Journal of Molecular Medicine 88 (11): 1113-1121. November 2010

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.
Michaelis, M. and Kleinschmidt, M.C. and Barth, S. and Rothweiler, F. and Geiler, J. and Breitling, R. and Mayer, B. and Deubzer, H. and Witt, O. and Kreuter, J. and Doerr, H.W. and Cinatl, J. and Cinatl, J.
Biochemical Pharmacology 79 (2): 130-136. 15 January 2010

HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth.
Milde, T. and Oehme, I. and Korshunov, A. and Kopp-Schneider, A. and Remke, M. and Northcott, P. and Deubzer, H.E. and Lodrini, M. and Taylor, M.D. and von Deimling, A. and Pfister, S. and Witt, O.
Clinical Cancer Research 16 (12): 3240-3252. 15 June 2010

ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Mueller, T. and Stein, U. and Poletti, A. and Garzia, L. and Rothley, M. and Plaumann, D. and Thiele, W. and Bauer, M. and Galasso, A. and Schlag, P. and Pankratz, M. and Zollo, M. and Sleeman, J.P.
Oncogene 29 (16): 2393-2403. 22 April 2010

The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.
Na, I.K. and Lu, S.X. and Yim, N.L. and Goldberg, G.L. and Tsai, J. and Rao, U. and Smith, O.M. and King, C.G. and Suh, D. and Hirschhorn-Cymerman, D. and Palomba, L. and Penack, O. and Holland, A.M. and Jenq, R.R. and Ghosh, A. and Tran, H. and Merghoub, T. and Liu, C. and Sempowski, G.D. and Ventevogel, M. and Beauchemin, N. and van den Brink, M.R.M.
Journal of Clinical Investigation 120 (1): 343-356. January 2010

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo.
Na, I.K. and Markley, J.C. and Tsai, J.J. and Yim, N.L. and Beattie, B.J. and Klose, A.D. and Holland, A.M. and Ghosh, A. and Rao, U.K. and Stephan, M.T. and Serganova, I. and Santos, E.B. and Brentjens, R.J. and Blasberg, R.G. and Sadelain, M. and van den Brink, M.R.M.
Blood 116 (11): e18-e25. 16 September 2010

A paired-end sequencing strategy to map the complex landscape of transcription initiation.
Ni, T. and Corcoran, D.L. and Rach, E.A. and Song, S. and Spana, E.P. and Gao, Y. and Ohler, U. and Zhu, J.
Nature Methods 7 (7): 521-527. July 2010

Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.
Norell, H. and Poschke, I. and Charo, J. and Wei, W.Z. and Erskine, C. and Piechocki, M.P. and Knutson, K.L. and Bergh, J. and Lidbrink, E. and Kiessling, R.
Journal of Translational Medicine 8 (1): 53. 7 June 2010

Promoting developmental transcription.
Ohler, U. and Wassarman, D.A.
Development 137 (1): 15-26. January 2010

I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development.
Orinska, Z. and Foeger, N. and Huber, M. and Marschall, J. and Mirghomizadeh, F. and Du, X. and Scheller, M. and Rosenstiel, P. and Goldmann, T. and Bollinger, A. and Beutler, B.A. and Bulfone-Paus, S.
Blood 116 (15): 2665-2675. 14 October 2010

Impact of membrane properties on uptake and transcytosis of colloidal nanocarriers across an epithelial cell barrier model.
Orthmann, A. and Zeisig, R. and Koklic, T. and Sentjurc, M. and Wiesner, B. and Lemm, M. and Fichtner, I.
Journal of Pharmaceutical Sciences 99 (5): 2423-2433. May 2010

The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery.
Parry, T.J. and Theisen, J.W.M. and Hsu, J.Y. and Wang, Y.L. and Corcoran, D.L. and Eustice, M. and Ohler, U. and Kadonaga, J.T.
Genes & Development 24 (18): 2013-2018. 15 September 2010

The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells.
Patzke, C. and Max, K.E. and Behlke, J. and Schreiber, J. and Schmidt, H. and Dorner, A.A. and Kroeger, S. and Henning, M. and Otto, A. and Heinemann, U. and Rathjen, F.G.
Journal of Neuroscience 30 (8): 2897-2910. 24 February 2010

A reference guide for tree analysis and visualization.
Pavlopoulos, G.A. and Soldatos, T.G. and Barbosa-Silva, A. and Schneider, R.
BioData Mining 3 : 1. 22 February 2010

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5.
Pavri, R. and Gazumyan, A. and Jankovic, M. and Di Virgilio, M. and Klein, I. and Ansarah-Sobrinho, C. and Resch, W. and Yamane, A. and Reina San-Martin, B. and Barreto, V. and Nieland, T.J. and Root, D.E. and Casellas, R. and Nussenzweig, M.C.
Cell 143 (1): 122-133. 1 October 2010

Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study.
Pelzer, U. and Arnold, D. and Govercin, M. and Stieler, J. and Doerken, B. and Riess, H. and Oettle, H.
BMC Cancer 10 (1): 86. 9 March 2010

Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth.
Penack, O. and Henke, E. and Suh, D. and King, C.G. and Smith, O.M. and Na, I.K. and Holland, A.M. and Ghosh, A. and Lu, S.X. and Jenq, R.R. and Liu, C. and Murphy, G.F. and Lu, T.T. and May, C. and Scheinberg, D.A. and Gao, D.C. and Mittal, V. and Heller, G. and Benezra, R. and van den Brink, M.R.M.
Journal of the National Cancer Institute 102 (12): 894-908. 16 June 2010

Common clonal origin of an acute B lymphoblastic leukemia and a Langerhans' cell sarcoma: evidence for hematopoietic plasticity.
Ratei, R. and Hummel, M. and Anagnostopoulos, I. and Jaehne, D. and Arnold, R. and Doerken, B. and Mathas, S. and Thomas, B. and Dudeck, O. and Ludwig, W.D. and Stein, H.
Haematologica 95 (9): 1461-1466. September 2010

Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch, A. and Seitz, S. and Baschant, U. and Schilling, A.F. and Illing, A. and Stride, B. and Kirilov, M. and Mandic, V. and Takacz, A. and Schmidt-Ullrich, R. and Ostermay, S. and Schinke, T. and Spanbroek, R. and Zaiss, M.M. and Angel, P.E. and Lerner, U.H. and David, J.P. and Reichardt, H.M. and Amling, M. and Schuetz, G. and Tuckermann, J.P.
Cell Metabolism 11 (6): 517-531. 9 June 2010

Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Reimann, M. and Lee, S. and Loddenkemper, C. and Doerr, J.R. and Tabor, V. and Aichele, P. and Stein, H. and Doerken, B. and Jenuwein, T. and Schmitt, C.A.
Cancer Cell 17 (3): 262-272. 16 March 2010

CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia.
Rhein, P. and Mitlohner, R. and Basso, G. and Gaipa, G. and Dworzak, M.N. and Kirschner-Schwabe, R. and Hagemeier, C. and Stanulla, M. and Schrappe, M. and Ludwig, W.D. and Karawajew, L. and Ratei, R.
Blood 115 (18): 3763-3771. 6 May 2010

The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins.
Rocks, O. and Gerauer, M. and Vartak, N. and Koch, S. and Huang, Z.P. and Pechlivanis, M. and Kuhlmann, J. and Brunsveld, L. and Chandra, A. and Ellinger, B. and Waldmann, H. and Bastiaens, P.I.
Cell 141 (3): 458-471. 30 April 2010

Rektumkarzinom - ein Musterbeispiel fuer Interdisziplinaritaet [Rectal carcinoma - a classic example of interdisciplinarity].
Roedel, C. and Schlag, P.M.
Onkologe 16 (8): 738-740. August 2010

Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB.
Rohwer, N. and Dame, C. and Haugstetter, A.M. and Wiedenmann, B. and Detjen, K. and Schmitt, C.A. and Cramer, T.
PLoS ONE 5 (8): e12038. 10 August 2010

Regulatory T cells in transplantation: does extracellular adenosine triphosphate metabolism through CD39 play a crucial role?
Salcido-Ochoa, F. and Tsang, J. and Tam, P. and Falk, K. and Roetzschke, O.
Transplantation Reviews 24 (2): 52-66. April 2010

Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60.
Schirling, C. and Heseding, C. and Heise, F. and Kesper, D. and Klebes, A. and Klein-Hitpass, L. and Vortkamp, A. and Hoffmann, D. and Saumweber, H. and Ehrenhofer-Murray, A.E.
Chromosoma 119 (1): 99-113. February 2010

Zwischen Hoffen und Bangen [Between hope and fear].
Schlag, P.M. and Bamberg, M.
Onkologe 16 (11): 11038-1040. November 2010

The power of reversibility regulating gene activities via tetracycline-controlled transcription.
Schoenig, K. and Bujard, H. and Gossen, M.
Methods in Enzymology 477 (C): 429-453. 2010

Neoadjuvant chemotherapy compared with surgery alone for locally advanced cancer of the stomach and cardia: European Organisation for Research and Treatment of Cancer Randomized Trial 40954.
Schuhmacher, C. and Gretschel, S. and Lordick, F. and Reichardt, P. and Hohenberger, W. and Eisenberger, C.F. and Haag, C. and Mauer, M.E. and Hasan, B. and Welch, J. and Ott, K. and Hoelscher, A. and Schneider, P.M. and Bechstein, W. and Wilke, H. and Lutz, M.P. and Nordlinger, B. and Van Cutsem, E. and Siewert, J.R. and Schlag, P.M.
Journal of Clinical Oncology 28 (35): 5210-5218. 10 December 2010

Evaluation of one- and two-color gene expression arrays for microbial comparative genome hybridization analyses in routine applications.
Schwarz, R. and Joseph, B. and Gerlach, G. and Schramm-Glueck, A. and Engelhard, K. and Frosch, M. and Mueller, T. and Schoen, C.
Journal of Clinical Microbiology 48 (9): 3105-3110. September 2010

Evolutionary distances in the twilight zone-a rational kernel approach.
Schwarz, R.F. and Fletcher, W. and Foerster, F. and Merget, B. and Wolf, M. and Schultz, J. and Markowetz, F.
PLoS ONE 5 (12): e15788. 31 December 2010

Purification, crystallization and preliminary X-ray analysis of human GIMAP2.
Schwefel, D. and Froehlich, C. and Daumke, O.
Acta Crystallographica Section F 66 (6): 725-729. 1 June 2010

Structural basis of oligomerization in septin-like GTPase of immunity-associated protein 2 (GIMAP2).
Schwefel, D. and Froehlich, C. and Eichhorst, J. and Wiesner, B. and Behlke, J. and Aravind, L. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 107 (47): 20299-20304. 23 November 2010

Impact of abutment rotation and angulation on marginal fit: theoretical considerations.
Semper, W. and Kraft, S. and Mehrhof, J. and Nelson, K.
International Journal of Oral & Maxillofacial Implants 25 (4): 752-758. July 2010

Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo.
Shalapour, S. and Deiser, K. and Sercan, O. and Tuckermann, J. and Minnich, K. and Willimsky, G. and Blankenstein, T. and Haemmerling, G.J. and Arnold, B. and Schueler, T.
European Journal of Immunology 40 (9): 2391-2400. September 2010

Leukemia-associated genetic aberrations in mesenchymal stem cells of children with acute lymphoblastic leukemia.
Shalapour, S. and Eckert, C. and Seeger, K. and Pfau, M. and Prada, J. and Henze, G. and Blankenstein, T. and Kammertoens, T.
Journal of Molecular Medicine 88 (3): 249-265. March 2010

Rapamycin and the transcription factor C/EBPbeta as a switch in osteoclast differentiation: implications for lytic bone diseases.
Smink, J.J. and Leutz, A.
Journal of Molecular Medicine 88 (3): 227-233. March 2010

Minimal amino acid exchange in human TCR constant regions fosters improved function of TCR gene-modified T cells.
Sommermeyer, D. and Uckert, W.
Journal of Immunology 184 (11): 6223-6231. 1 June 2010

MACC1 - more than metastasis? Facts and predictions about a novel gene.
Stein, U. and Dahlmann, M. and Walther, W.
Journal of Molecular Medicine 88 (1): 11-18. January 2010

Armadillo motifs involved in vesicular transport.
Striegl, H. and Andrade-Navarro, M.A. and Heinemann, U.
PLoS ONE 5 (2): e8991. 1 February 2010

Role of Epiprofin, a zinc-finger transcription factor, in limb development.
Talamillo, A. and Delgado, I. and Nakamura, T. and de-Vega, S. and Yoshitomi, Y. and Unda, F. and Birchmeier, W. and Yamada, Y. and Ros, M.A.
Developmental Biology 337 (2): 363-374. 15 January 2010

A modified EBMT risk score and the hematopoietic cell transplantation-specific comorbidity index for pre-transplant risk assessment in adult acute lymphoblastic leukemia.
Terwey, T.H. and Hemmati, P.G. and Martus, P. and Dietz, E. and Vuong, L.G. and Massenkeil, G. and Doerken, B. and Arnold, R.
Haematologica 95 (5): 810-818. May 2010

Mapping the complexity of transcription control in higher eukaryotes.
Tomancak, P. and Ohler, U.
Genome Biology 11 (4): 115. 30 April 2010

Uncovering a unique role for DNA methylation in hematopoietic and leukemic stem cells.
Vockentanz, L. and Broeske, A.M. and Rosenbauer, F.
Cell Cycle 9 (4): 640-641. February 2010

Reduced-intensity conditioning using fludarabine and antithymocyte globulin alone allows stable engraftment in a patient with Dyskeratosis congenita.
Vuong, L.G. and Hemmati, P.G. and Neuburger, S. and Terwey, T.H. and Vulliamy, T. and Dokal, I. and Le Coutre, P. and Doerken, B. and Arnold, R.
Acta Haematologica 124 (4): 200-203. December 2010

Jet-injection of short hairpin RNA-encoding vectors into tumor cells.
Walther, W. and Stein, U. and Lage, H.
Methods in Molecular Biology 629 : 123-139. 2010

In silico screening for pathogenesis related-2 gene candidates in Vigna uguiculata transcriptome.
Wanderley-Nogueira, A.C. and Da Mota Soares-Cavalcanti, N. and Belarmino, L.C. and Barbosa-Silva, A. and Kido, E.A. and Do Monte, S.J.H. and Pandolfi, V. and Calsa-Junior, T. and Benko-Iseppon, A.M.
Lecture Notes in Computer Science 6160 : 70-81. 2010

Wnt signaling in stem and cancer stem cells.
Wend, P. and Holland, J.D. and Ziebold, U. and Birchmeier, W.
Seminars in Cell & Developmental Biology 21 (8): 855-863. October 2010

Inhibition of metastasis in a murine 4T1 breast cancer model by liposomes preventing tumor cell-platelet interactions.
Wenzel, J. and Zeisig, R. and Fichtner, I.
Clinical and Experimental Metastasis 27 (1): 25-34. January 2010

Inhibition of pulmonary metastasis in a human MT3 breast cancer xenograft model by dual liposomes preventing intravasal fibrin clot formation.
Wenzel, J. and Zeisig, R. and Haider, W. and Habedank, S. and Fichtner, I.
Breast Cancer Research and Treatment 121 (1): 13-22. May 2010

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.
Werth, M. and Walentin, K. and Aue, A. and Schoenheit, J. and Wuebken, A. and Pode-Shakked, N. and Vilianovitch, L. and Erdmann, B. and Dekel, B. and Bader, M. and Barasch, J. and Rosenbauer, F. and Luft, F.C. and Schmidt-Ott, K.M.
Development 137 (22): 3835-3845. November 2010

C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
Wethmar, K. and Begay, V. and Smink, J.J. and Zaragoza, K. and Wiesenthal, V. and Doerken, B. and Calkhoven, C.F. and Leutz, A.
Genes & Development 24 (1): 15-20. 1 January 2010

Upstream open reading frames: molecular switches in (patho)physiology.
Wethmar, K. and Smink, J.J. and Leutz, A.
BioEssays 32 (10): 885-893. October 2010

TRANSAT-- method for detecting the conserved helices of functional RNA structures, including transient, pseudo-knotted and alternative structures.
Wiebe, N.J.P. and Meyer, I.M.
PLoS Computational Biology 6 (6): e1000823. 24 June 2010

Viel Bewegung in der interdisziplinaeren Therapie des Nierenzellkarzinoms [A lot of movement in the interdisciplinary treatment of renal cell carcinoma].
Wiegel, T. and Schlag, P.M.
Onkologe 16 (2): 119-120. February 2010

Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting.
Wilke, S. and Krausze, J. and Gossen, M. and Groebe, L. and Jaeger, V. and Gherardi, E. and van den Heuvel, J. and Buessow, K.
Protein Science 19 (6): 1264-1271. June 2010

The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation.
Winter, S. and Loddenkemper, C. and Aebischer, A. and Raebel, K. and Hoffmann, K. and Meyer, T.F. and Lipp, M. and Hoepken, U.E.
Journal of Molecular Medicine 88 (11): 1169-1180. November 2010

Role of EBAG9 protein in coat protein complex I-dependent glycoprotein maturation and secretion processes in tumor cells.
Wolf, J. and Reimer, T.A. and Schuck, S. and Rueder, C. and Gerlach, K. and Mueller, E.C. and Otto, A. and Doerken, B. and Rehm, A.
FASEB Journal 24 (10): 4000-4019. October 2010

Fatal immune haemolysis due to antibodies to individual metabolites of 5-fluorouracil.
Yuerek, S. and Riess, H. and Kreher, S. and Doerken, B. and Salama, A.
Transfusion Medicine 20 (4): 265-268. 1 August 2010

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.
Zaltsman, Y. and Shachnai, L. and Yivgi-Ohana, N. and Schwarz, M. and Maryanovich, M. and Houtkooper, R.H. and Vaz, F.M. and De Leonardis, F. and Fiermonte, G. and Palmieri, F. and Gillissen, B. and Daniel, P.T. and Jimenez, E. and Walsh, S. and Koehler, C.M. and Roy, S.S. and Walter, L. and Hajnoczky, G. and Gross, A.
Nature Cell Biology 12 (6): 553-562. June 2010

Repression of transcriptional activity of C/EBPα by E2F-DP complexes.
Zaragoza, K. and Bégay, V. and Schuetz, A. and Heinemann, U. and Leutz, A.
Molecular and Cellular Biology 30 (9): 2293-2304. May 2010

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.
Zhang, G. and Hoersch, S. and Amsterdam, A. and Whittaker, C.A. and Lees, J.A. and Hopkins, N.
Proceedings of the National Academy of Sciences of the United States of America 107 (39): 16940-16945. 28 September 2010

BCR-ABL positive cells and chronic myeloid leukemia in immune suppressed organ transplant recipients.
le Coutre, P. and Reinke, P. and Neuhaus, R. and Trappe, R. and Ringel, F. and Lalancette, M. and Hemmati, P.G. and Doerken, B. and Daniel, P.T.
European Journal of Haematology 84 (1): 26-33. 1 January 2010

2009

In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B.
Abu Ajaj, K. and Graeser, R. and Fichtner, I. and Kratz, F.
Cancer Chemotherapy and Pharmacology 64 (2): 413-418. July 2009

CCR7-deficient mice develop atypically persistent germinal centers in response to thymus-independent type 2 antigens.
Achtman, A.H. and Hoepken, U.E. and Bernert, C. and Lipp, M.
Journal of Leukocyte Biology 85 (3): 409-417. March 2009

Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression.
Anders, M. and Vieth, M. and Roecken, C. and Ebert, M. and Pross, M. and Gretschel, S. and Schlag, P.M. and Wiedenmann, B. and Kemmner, W. and Hoecker, M.
British Journal of Cancer 100 (2): 352-359. 27 January 2009

Colon cancer metastasis: MACC1 and Met as metastatic pacemakers.
Arlt, F. and Stein, U.
International Journal of Biochemistry and Cell Biology 41 (12): 2356-2359. December 2009

Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome.
Babaylova, E. and Graifer, D. and Malygin, A. and Stahl, J. and Shatsky, I. and Karpova, G.
Nucleic Acids Research 37 (4): 1141-1151. March 2009

Binding of Drosophila ORC proteins to anaphase chromosomes requires cessation of mitotic cyclin-dependent kinase activity.
Baldinger, T. and Gossen, M.
Molecular and Cellular Biology 29 (1): 140-149. January 2009

Active promoters and insulators are marked by the centrosomal protein 190.
Bartkuhn, M. and Straub, T. and Herold, M. and Herrmann, M. and Rathke, C. and Saumweber, H. and Gilfillan, G.D. and Becker, P.B. and Renkawitz, R.
EMBO Journal 28 (7): 877-888. 8 April 2009

Upgrade of an optical navigation system with a permanent electromagnetic position control : A first step towards "navigated control" for liver surgery.
Beller, S. and Eulenstein, S. and Lange, T. and Huenerbein, M. and Schlag, P.M.
Journal of Hepato-Biliary-Pancreatic Surgery 16 (2): 165-170. March 2009

A new measure to assess the difficulty of liver resection.
Beller, S. and Eulenstein, S. and Lange, T. and Niederstrasser, M. and Huenerbein, M. and Schlag, P.M.
European Journal of Surgical Oncology 35 (1): 59-64. January 2009

A kinome of 2600 in the ciliate Paramecium tetraurelia.
Bemm, F. and Schwarz, R. and Foerster, F. and Schultz, J.
FEBS Letters 583 (22): 3589-3592. 19 November 2009

High-throughput omics technologies: Potential tools for the investigation of influences of EMF on biological systems.
Blankenburg, M. and Haberland, L. and Elvers, H.D. and Tannert, C. and Jandrig, B.
Current Genomics 10 (2): 86-92. April 2009

Efficacy of MS-275, a selective inhibitor of class I histone deacetylases, in human colon cancer models.
Bracker, T.U. and Sommer, A. and Fichtner, I. and Faus, H. and Haendler, B. and Hess-Stumpp, H.
International Journal of Oncology 35 (4): 909-920. October 2009

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, A.M. and Vockentanz, L. and Kharazi, S. and Huska, M.R. and Mancini, E. and Scheller, M. and Kuhl, C. and Enns, A. and Prinz, M. and Jaenisch, R. and Nerlov, C. and Leutz, A. and Andrade-Navarro, M.A. and Jacobsen, S.E. and Rosenbauer, F.
Nature Genetics 41 (11): 1207-1215. November 2009

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Buonamici, S. and Trimarchi, T. and Ruocco, M.G. and Reavie, L. and Cathelin, S. and Mar, B.G. and Klinakis, A. and Lukyanov, Y. and Tseng, J.C. and Sen, F. and Gehrie, E. and Li, M. and Newcomb, E. and Zavadil, J. and Meruelo, D. and Lipp, M. and Ibrahim, S. and Efstratiadis, A. and Zagzag, D. and Bromberg, J.S. and Dustin, M.L. and Aifantis, I.
Nature 459 (7249): 1000-1004. 18 June 2009

Sentinel node biopsy for the individualization of surgical strategy for cure of early-stage colon cancer.
Cahill, R.A. and Bembenek, A. and Sirop, S. and Waterhouse, D.F. and Schneider, W. and Leroy, J. and Wiese, D. and Beutler, T. and Bilchik, A. and Saha, S. and Schlag, P.M.
Annals of Surgical Oncology 16 (8): 2170-2180. August 2009

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Callen, E. and Jankovic, M. and Wong, N. and Zha, S. and Chen, H.T. and Difilippantonio, S. and Di Virgilio, M. and Heidkamp, G. and Alt, F.W. and Nussenzweig, A. and Nussenzweig, M.
Molecular Cell 34 (3): 285-297. 15 May 2009

The spatio-temporal pattern of testis organogenesis in mammals - insights from the mole.
Carmona, F.D. and Lupianez, D.G. and Martin, J.E. and Burgos, M. and Jimenez, R. and Zurita, F.
International Journal of Developmental Biology 53 (7): 1035-1044. 2009

SOX9 is not required for the cellular events of testicular organogenesis in XX mole ovotestes.
Carmona, F.D. and Lupianez, D.G. and Real, F.M. and Burgos, M. and Zurita, F. and Jimenez, R.
Journal of Experimental Zoology Part B : Molecular and Developmental Evolution 312 (7): 734-748. 15 November 2009

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum.
Clerc, S. and Hirsch, C. and Oggier, D.M. and Deprez, P. and Jakob, C. and Sommer, T. and Aebi, M.
Journal of Cell Biology 184 (1): 159-172. 12 January 2009

Treatment of oesophageal anastomotic leaks by temporary stenting with self-expanding plastic stents.
Dai, Y.Y. and Gretschel, S. and Dudeck, O. and Rau, B. and Schlag, P.M. and Huenerbein, M.
British Journal of Surgery 96 (8): 887-891. August 2009

PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin.
Di Virgilio, M. and Ying, C.Y. and Gautier, J.
DNA Repair 8 (11): 1311-1320. 2 November 2009

Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies.
Diaz Miqueli, A. and Rolff, J. and Lemm, M. and Fichtner, I. and Perez, R. and Montero, E.
British Journal of Cancer 100 (6): 950-958. 24 March 2009

Enhancement of tumour-specific immune responses in vivo by 'MHC Loading-Enhancer' (MLE).
Dickhaut, K. and Hoepner, S. and Eckhard, J. and Wiesmueller, K.H. and Schindler, L. and Jung, G. and Falk, K. and Roetzschke, O.
PLoS ONE 4 (9): e6811. 7 September 2009

Mobile phones and health: Media coverage study of German newspapers on possible adverse health effects of mobile phone use.
Elvers, H.D. and Jandrig, B. and Grummich, K. and Tannert, C.
Health, Risk & Society 11 (2): 165-179. April 2009

Public participation in technology evaluation and risk communication.
Elvers, H.D. and Tannert, C.
In: Electromagnetic Field Exposure: Risk Communication in the context of Uncertainty. UNSPECIFIED, 265-274. 2009

Escalated-dose BEACOPP in the treatment of patients with advanced-stage Hodgkin's lymphoma: 10 years of follow-up of the GHSG HD9 study.
Engert, A. and Diehl, V. and Franklin, J. and Lohri, A. and Doerken, B. and Ludwig, W.D. and Koch, P. and Haenel, M. and Pfreundschuh, M. and Wilhelm, M. and Truemper, L. and Aulitzky, W.E. and Bentz, M. and Rummel, M. and Sezer, O. and Mueller-Hermelink, H.K. and Hasenclever, D. and Loeffler, M.
Journal of Clinical Oncology 27 (27): 4548-4554. 20 September 2009

Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Fabricius, E.M. and Kruse-Boitschenko, U. and Khoury, R. and Wildner, G.P. and Raguse, J.D. and Klein, M.
International Journal of Oncology 34 (5): 1257-1279. May 2009

Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Fabricius, E.M. and Kruse-Boitschenko, U. and Khoury, R. and Wildner, G.P. and Raguse, J.D. and Klein, M. and Hoffmeister, B.
International Journal of Oncology 35 (6): 1377-1394. December 2009

Severe thrombocytopenia in a patient with metastatic renal cell carcinoma.
Floercken, A. and Loew, A. and Koch, M. and Gebauer, B. and Doerken, B. and Riess, H.
Onkologie 32 (11): 670-672. November 2009

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J. and Morkel, M. and Besser, D. and Budczies, J. and Kosel, F. and Brembeck, F.H. and Stein, U. and Fichtner, I. and Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

Cellular fingerprints: a novel approach using large-scale cancer cell line data for the identification of potential anticancer agents.
Fuellbeck, M. and Dunkel, M. and Hossbach, J. and Daniel, P.T. and Preissner, R.
Chemical Biology & Drug Design 74 (5): 439-448. November 2009

Computer-assisted identification of small-molecule Bcl-2 modulators.
Fuellbeck, M. and Gebhardt, N. and Hossbach, J. and Daniel, P.T. and Preissner, R.
Computational Biology and Chemistry 33 (6): 451-456. December 2009

NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation.
Gargiulo, G. and Levy, S. and Bucci, G. and Romanenghi, M. and Fornasari, L. and Beeson, K.Y. and Goldberg, S.M. and Cesaroni, M. and Ballarini, M. and Santoro, F. and Bezman, N. and Frige, G. and Gregory, P.D. and Holmes, M.C. and Strausberg, R.L. and Pelicci, P.G. and Urnov, F.D. and Minucci, S.
Developmental Cell 16 (3): 466-481. 17 March 2009

Epigenomic profiling of cancer cells.
Gargiulo, G. and Minucci, S.
International Journal of Biochemistry and Cell Biology 41 (1): 127-135. January 2009

AIDS-Erreger aus dem Militaerlabor - Ignoranz oder bewusste Desinformation?
Geissler, E.
In: Natur und Kultur. Biologie im Spannungsfeld von Naturphilosophie und Darwinismus. VWB Verlag fuer Wissenschaft und Bildung, Berlin, 489-508. ISBN 978-3-86135-393-5 2009

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S. and Wende, H. and Paul, F.E. and Cheret, C. and Garratt, A.N. and Zurborg, S. and Feinberg, K. and Besser, D. and Schulz, H. and Peles, E. and Selbach, M. and Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease.
Guenther, U.P. and Handoko, L. and Varon, R. and Stephani, U. and Tsao, C.Y. and Mendell, J.R. and Lützkendorf, S. and Hübner, C. and von Au, K. and Jablonka, S. and Dittmar, G. and Heinemann, U. and Schuetz, A. and Schuelke, M.
Journal of Molecular Medicine 87 (1): 31-41. January 2009

Late-fluorescence mammography assesses tumor capillary permeability and differentiates malignant from benign lesions.
Hagen, A. and Grosenick, D. and Macdonald, R. and Rinneberg, H. and Burock, S. and Warnick, P. and Poellinger, A. and Schlag, P.M.
Optics Express 17 (19): 17016-17033. 14 September 2009

Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax.
Handrick, R. and Ganswindt, U. and Faltin, H. and Goecke, B. and Daniel, P.T. and Budach, W. and Belka, C. and Jendrossek, V.
Radiotherapy and Oncology 90 (3): 413-421. March 2009

The dipole moment of the electron carrier adrenodoxin is not critical for redox partner interaction and electron transfer.
Hannemann, F. and Guyot, A. and Zoellner, A. and Mueller, J.J. and Heinemann, U. and Bernhardt, R.
Journal of Inorganic Biochemistry 103 (7): 997-1004. July 2009

Oral administration of a soluble 1-3, 1-6 beta-glucan during prophylactic survivin peptide vaccination diminishes growth of a B cell lymphoma in mice.
Harnack, U. and Eckert, K. and Fichtner, I. and Pecher, G.
International Immunopharmacology 9 (11): 1298-1303. October 2009

Expression, purification and preliminary X-ray crystallographic analysis of the chicken MHC class I molecule YF1*7.1.
Hee, C.S. and Gao, S. and Miller, M.M. and Goto, R.M. and Ziegler, A. and Daumke, O. and Uchanska-Ziegler, B.
Acta Crystallographica Section F 65 (Pt 4): 422-425. 1 April 2009

Angiotensin-(1-7) stimulates hematopoietic progenitor cells in vitro and in vivo.
Heringer-Walther, S. and Eckert, K. and Schumacher, S.M. and Uharek, L. and Wulf-Goldenberg, A. and Gembardt, F. and Fichtner, I. and Schultheiss, H.P. and Rodgers, K. and Walther, T.
Haematologica 94 (6): 857-860. June 2009

The ubiquitylation machinery of the endoplasmic reticulum.
Hirsch, C. and Gauss, R. and Horn, S.C. and Neuber, O. and Sommer, T.
Nature 458 (7237): 453-460. 26 March 2009

Why we don't do, what we know?
Hoeffken, K. and Bamberg, M. and Schlag, P.M.
Onkologe 15 (1): 84. January 2009

Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
Hoffmann, J. and Fichtner, I. and Lemm, M. and Lienau, P. and Hess-Stumpp, H. and Rotgeri, A. and Hofmann, B. and Klar, U.
Neuro Oncology 11 (2): 158-166. April 2009

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C. and Hanna, J. and Hirsch, C. and Volkwein, C. and Schütz, A. and Heinemann, U. and Sommer, T. and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009

Inhibiting the inhibitors: retro-inverso Smac peptides.
Hossbach, J. and Michalsky, E. and Henklein, P. and Jaeger, M. and Daniel, P.T. and Preissner, R.
Peptides 30 (12): 2374-2379. December 2009

Ductoscopy of intraductal neoplasia of the breast.
Huenerbein, M. and Raubach, M. and Dai, K. and Schlag, P.M.
In: Minimally Invasive Breast Biopsies. Recent Results in Cancer Research, 173 . Springer, Berlin, 129-136. ISBN 978-3-540-31403-5 2009

Inhibition of the ER Ca2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis.
Janssen, K. and Horn, S. and Niemann, M.T. and Daniel, P.T. and Schulze-Osthoff, K. and Fischer, U.
Journal of Cell Science 122 (Pt 24): 4481-4491. 15 December 2009

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation.
Jenq, R.R. and King, C.G. and Volk, C. and Suh, D. and Smith, O.M. and Rao, U.K. and Yim, N.L. and Holland, A.M. and Lu, S.X. and Zakrzewski, J.L. and Goldberg, G.L. and Diab, A. and Alpdogan, O. and Penack, O. and Na, I.K. and Kappel, L.W. and Wolchok, J.D. and Houghton, A.N. and Perales, M.A. and van den Brink, M.R.M.
Blood 113 (7): 1574-1580. 12 February 2009

Single-molecule force spectroscopy distinguishes target binding modes of calmodulin.
Junker, J.P. and Rief, M.
Proceedings of the National Academy of Sciences of the United States of America 106 (34): 14361-14366. 25 August 2009

Ligand-dependent equilibrium fluctuations of single calmodulin molecules.
Junker, J.P. and Ziegler, F. and Rief, M.
Science 323 (5914): 633-637. 30 January 2009

Making and circumventing tolerance to cancer.
Kammertoens, T. and Blankenstein, T.
European Journal of Immunology 39 (9): 2345-2353. September 2009

Developmental signaling in myocardial progenitor cells: A comprehensive view of Bmp- and Wnt/beta-catenin signaling.
Klaus, A. and Birchmeier, W.
Pediatric Cardiology 30 (5): 609-616. July 2009

Translationale Melanomforschung ist nach wie vor schwer in praktische Erfolge umzumuenzen [Translational melamoma research remains difficult to transform into practical success].
Kleeberg, U.R. and Schlag, P.M.
Onkologe 15 (8): 735-736. August 2009

Identification of brain- and bone-specific breast cancer metastasis genes.
Klein, A. and Olendrowitz, C. and Schmutzler, R. and Hampl, J. and Schlag, P.M. and Maass, N. and Arnold, N. and Wessel, R. and Ramser, J. and Meindl, A. and Scherneck, S. and Seitz, S.
Cancer Letters 276 (2): 212-220. 18 April 2009

CD49d provides access to 'untouched' human Foxp3+ Treg free of contaminating effector cells.
Kleinewietfeld, M. and Starke, M. and Mitri, D.D. and Borsellino, G. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 113 (4): 827-836. 22 January 2009

Crystal structure of KorA bound to operator DNA: insight into repressor cooperation in RP4 gene regulation.
Koenig, B. and Mueller, J.J. and Lanka, E. and Heinemann, U.
Nucleic Acids Research 37 (6): 1915-1924. April 2009

Purification and preliminary X-ray crystallographic studies of beta-microseminoprotein f