2024
Sensor macrophages derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs.
Abdin, S.M., Mansel, F., Rafiei Hashtchin, A., Ackermann, M., Hansen, G., Becker, B., Kick, B., Pham, N., Dietz, H., Schaniel, C., Martin, U., Spreitzer, I. and Lachmann, N.
Biofabrication 16
(3): 035017.
July 2024
The patient-reported outcomes for the new brand-generic teriflunomide in relapsing-remitting multiple sclerosis.
Abolfazli, R., Nabavi, S.M., Azimi, A., Nahayati, M., Gharagozli, K., Torabi, H., Ghazaeian, M., Rezagholi, Z. and Samadzadeh, S.
Clinical Neurology and Neurosurgery 246
: 108552.
November 2024
Cognitive-motor interference in multiple sclerosis and healthy controls: results from single, dual, and triple task posturography.
Althoff, P., Rosenthal, F., Dorsch, E.M., Drebinger, D., Arsenova, R., Chorschew, A., Rosenkranz, S.C., Bellmann-Strobl, J., Heesen, C., Paul, F., Weygandt, M. and Schmitz-Hübsch, T.
Exploration of Neuroprotective Therapy 4
: 273-287.
12 June 2024
Emerging MRI and biofluid biomarkers in the diagnosis and prognosis of multiple sclerosis.
Anderhalten, L., Wohlrab, F. and Paul, F.
Lancet Regional Health - Europe 44
: 101023.
September 2024
Predicting disease severity in multiple sclerosis using multimodal data and machine learning.
Andorra, M., Freire, A., Zubizarreta, I., de Rosbo, N.K., Bos, S.D., Rinas, M., Høgestøl, E.A., de Rodez Benavent, S.A., Berge, T., Brune-Ingebretse, S., Ivaldi, F., Cellerino, M., Pardini, M., Vila, G., Pulido-Valdeolivas, I., Martinez-Lapiscina, E.H., Llufriu, S., Saiz, A., Blanco, Y., Martinez-Heras, E., Solana, E., Bäcker-Koduah, P., Behrens, J., Kuchling, J., Asseyer, S., Scheel, M., Chien, C., Zimmermann, H., Motamedi, S., Kauer-Bonin, J., Brandt, A., Saez-Rodriguez, J., Alexopoulos, L.G., Paul, F., Harbo, H.F., Shams, H., Oksenberg, J., Uccelli, A., Baeza-Yates, R. and Villoslada, P.
Journal of Neurology 271
(3): 1133-1149.
March 2024
Sex ratio and age of onset in AQP4 antibody-associated NMOSD: a review and meta-analysis.
Arnett, S., Chew, S.H., Leitner, U., Hor, J.Y., Paul, F., Yeaman, M.R., Levy, M., Weinshenker, B.G., Banwell, B.L., Fujihara, K., Abboud, H., Dujmovic Basuroski, I., Arrambide, G., Neubrand, V. E., Quan, C., Melamed, E., Palace, J., Sun, J., Asgari, N. and Broadley, S.A
Journal of Neurology 271
(8): 4794-4812.
August 2024
Regional spinal cord volumes and pain profiles in AQP4-IgG + NMOSD and MOGAD.
Asseyer, S., Zmira, O., Busse, L., Pflantzer, B., Schindler, P., Schmitz-Hübsch, T., Paul, F. and Chien, C.
Frontiers in Neurology 15
: 1308498.
26 January 2024
ADAM19 cleaves the PTH receptor and associates with brachydactyly type E.
Aydin, A., Klenk, C., Nemec, K., Işbilir, Ali, Martin, L.M., Zauber, H., Rrustemi, T., Toka, H.R., Schuster, H., Gong, M., Stricker, S., Bock, A., Bähring, S., Selbach, M., Lohse, M.J. and Luft, F.C.
Life Science Alliance 7
(4): e202302400.
April 2024
Fasting, ketogenic and anti-inflammatory diets stabilized active relapsing-remitting multiple sclerosis over 18 months, a randomized, controlled study.
Bahr, Lina Samira, Bellmann-Strobl, J., Koppold, D.A., Rust, R., Schmitz-Hübsch, T., Olszewska, M., Stadlbauer, J., Bock, M., Scheel, M., Chien, C., Multmeier, J., Krannich, A., Michalsen, A., Paul, F. and Mähler, A.
medRxiv
: 2024.08.13.24311863.
14 August 2024
In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia.
Bakina, O., Conrad, T., Mitic, N., Vidal, R.O., Obrusnik, T., Sai, S., Nolte, C., Semtner, M. and Kettenmann, H.
PLoS ONE 19
(7): e0302376.
11 July 2024
Undetected neuromuscular disease in patients after heart transplantation.
Bekele, B.M., Gazzerro, E., Schoenrath, F., Falk, V., Rost, S., Hoerning, S., Jelting, Y., Zaum, A.K., Spuler, S. and Knierim, J.
International Journal of Molecular Sciences 25
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17 July 2024
B cell and aquaporin-4 antibody relationships with neuromyelitis optica spectrum disorder activity.
Bennett, J.L., Pittock, S.J., Paul, F., Kim, H.J., Irani, S.R., O'Connor, K.C., Patterson, K.R., Smith, M.A., Gunsior, M., Mittereder, N., Rees, W.A., Cimbora, D. and Cree, B.A.C.
Annals of Clinical and Translational Neurology
2024
(In Press)
Caveolin-3 and Caveolin-1 interaction decreases channel dysfunction due to Caveolin-3 mutations.
Benzoni, P., Gazzerro, E., Fiorillo, C., Baratto, S., Bartolucci, C., Severi, S., Milanesi, R., Lippi, M., Langione, M., Murano, C., Meoni, C., Popolizio, V., Cospito, A., Baruscotti, M., Bucchi, A. and Barbuti, A.
International Journal of Molecular Sciences 25
(2): 980.
2 January 2024
The networking brain: how extracellular matrix, cellular networks, and vasculature shape the in vivo mechanical properties of the brain.
Bergs, J., Morr, A.S., Silva, R.V., Infante-Duarte, C. and Sack, I.
Advanced Science 11
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21 August 2024
Cerebrospinal fluid findings in patients with neurological manifestations in post-COVID-19 syndrome.
Boesl, F., Goereci, Y., Gerhard, A., Bremer, B., Raeder, V., Schweitzer, F., Hoppmann, U., Behrens, J., Bellmann-Strobl, J., Paul, F., Wildemann, B., Jarius, S., Prüss, H., Audebert, H.J., Warnke, C. and Franke, C.
Journal of Neurology 271
(1): 59-70.
January 2024
Daylight exposure and mood in real life: direct association and mediating role of sleep and routine regularity.
Bonatto, F.S., Pilz, L.K., Borges, R.B., Xavier, N.B., Tonon, A.C., do Amaral, F.G. and Hidalgo, M.P.L.
Chronobiology International 41
(8): 1128-1141.
26 July 2024
Polyglutamine disease proteins: Commonalities and differences in interaction profiles and pathological effects.
Bonsor, M., Ammar, O., Schnoegl, S., Wanker, E.E. and Silva Ramos, E.
Proteomics 24
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June 2024
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Brenner, D., Sieverding, K., Srinidhi, J., Zellner, S., Secker, C., Yilmaz, R., Dyckow, J., Amr, S., Ponomarenko, A., Tunaboylu, E., Douahem, Y., Schlag, J.S., Rodríguez Martínez, L., Kislinger, G., Niemann, C., Nalbach, K., Ruf, W.P., Uhl, J., Hollenbeck, J., Schirmer, L., Catanese, A., Lobsiger, C.S., Danzer, K.M., Yilmazer-Hanke, D., Münch, C., Koch, P., Freischmidt, A., Fetting, M., Behrends, C., Parlato, R. and Weishaupt, J.H.
Journal of Experimental Medicine 221
(5): e20221190.
22 March 2024
The lack of synapsin alters presynaptic plasticity at hippocampal mossy fibers in male mice.
Bruentgens, F., Velasquez, L.M., Stumpf, A., Parthier, D., Breustedt, J., Benfenati, F., Milovanovic, D., Schmitz, D. and Orlando, M.
eNeuro 11
(7): ENEURO.0330-23.2024.
July 2024
Optogenetic determination of dynamic and cell-type-specific inhibitory reversal potentials.
Burman, R.J., Diviney, T., Călin, A., Gothard, G., Jouhanneau, J.S., Poulet, J.F.A., Sen, A. and Akerman, C.J.
Journal of Neuroscience 44
(20): e1392232024.
15 May 2024
Establishment of a high-content compatible platform to assess effects of monocyte-derived factors on neural stem cell proliferation and differentiation.
Campo Garcia, J., Bueno, R.J., Salla, M., Martorell-Serra, I., Seeger, B., Akbari, N., Sperber, P., Stachelscheid, H., Infante-Duarte, C., Paul, F. and Starossom, S.C.
Scientific Reports 14
(1): 12167.
28 May 2024
The real-world applicability of the 2023 international myelin oligodendrocyte glycoprotein antibody-associated disease criteria in a Latin American cohort.
Carnero Contentti, E., Pestchanker, C., Ciampi, E., Castro Suarez, S., Caparo Zamalloa, C., Daccach Marques, V., Messias, K., Gortari, J.I., Tkachuk, V., Silva, B., Mainella, C., Reyes, S., Toro, J., Rodriguez, J., Correa-Diaz, E., Rojas, J.I. and Paul, F.
European Journal of Neurology
: e16445.
17 September 2024
(In Press)
Touch sensation requires the mechanically gated ion channel ELKIN1.
Chakrabarti, S., Klich, J.D., Khallaf, M.A., Hulme, A.J., Sánchez-Carranza, O., Baran, Z.M., Rossi, A., Huang, A.T.L., Pohl, T., Fleischer, R., Fürst, C., Hammes, A., Bégay, V., Hörnberg, H., Finol-Urdaneta, R.K., Poole, K., Dottori, M. and Lewin, G.
Science 383
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1 March 2024
Mechanistic insights into the basis of widespread RNA localization.
Chekulaeva, M.
Nature Cell Biology 26
(7): 1037-1046.
July 2024
Reevaluating the relevance of F-FDG PET findings for diagnosis of neurosarcoidosis: a case series.
Chen, J., Metzger, G., Furth, C., Bohner, G. and Siffrin, V.
Neurological Research and Practice 6
(1): 12.
25 January 2024
Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling.
Cheng, J., Li, M., Motta, E., Barci, D., Song, W., Zhou, D., Li, G., Zhu, S., Yang, A., Vaillant, B.D., Imhof, A., Forné, I., Spiegl-Kreinecker, S., Zhang, N., Katayama, H., Bhat, K.P.L., Flüh, C., Kälin, R.E. and Glass, R.
Cell Reports Medicine 5
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20 August 2024
Altered brain perfusion and oxygen levels relate to sleepiness and attention in post-COVID syndrome.
Chien, C., Heine, J., Khalil, A., Schlenker, L., Hartung, T.J., Boesl, F., Schwichtenberg, K., Rust, R., Bellmann-Strobl, J., Franke, C., Paul, F. and Finke, C.
Annals of Clinical and Translational Neurology 11
(8): 2016-2029.
2024
CD4+ T cell mitochondrial genotype in Multiple Sclerosis: a cross-sectional and longitudinal analysis.
Cortes-Figueiredo, F., Asseyer, S., Chien, C., Zimmermann, H.G., Ruprecht, K., Schmitz-Hübsch, T., Bellmann-Strobl, J., Paul, F. and Morais, V.A.
Scientific Reports 14
(1): 7507.
29 March 2024
Grey matter atrophy and its relationship with white matter lesions in patients with myelin oligodendrocyte glycoprotein antibody-associated disease, aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder, and multiple sclerosis.
Cortese, R., Battaglini, M., Prados, F., Gentile, G., Luchetti, L., Bianchi, A., Haider, L., Jacob, A., Palace, J., Messina, S., Paul, F., Marignier, R., Durand-Dubief, F., de Medeiros Rimkus, C., Apostolos Pereira, S.L., Sato, D.K., Filippi, M., Rocca, M.A., Cacciaguerra, L., Rovira, À., Sastre-Garriga, J., Arrambide, G., Liu, Y., Duan, Y., Gasperini, C., Tortorella, C., Ruggieri, S., Amato, M.P., Ulivelli, M., Groppa, S., Grothe, M., Llufriu, S., Sepulveda, M., Lukas, C., Bellenberg, B., Schneider, R., Sowa, P., Celius, E.G., Pröbstel, A.K., Granziera, C., Yaldizli, Ö., Müller, J., Stankoff, B., Bodini, B., Barkhof, F., Ciccarelli, O. and De Stefano, N.
Annals of Neurology 92
(2): 276-288.
23 May 2024
Safety and efficacy of inebilizumab for the treatment of neuromyelitis optica spectrum disorder: end-of-study results from the open-label period of the N-MOmentum trial.
Cree, B.A.C., Kim, H.J., Weinshenker, B.G., Pittock, S.J., Wingerchuk, D.M., Fujihara, K., Paul, F., Cutter, G.R., Marignier, R., Green, A.J., Aktas, O., Hartung, H.P., She, D., Rees, W., Smith, M., Cimbora, D., Katz, E. and Bennett, J.L.
Lancet Neurology 23
(6): 588-602.
June 2024
Genetic identification of medullary neurons underlying congenital hypoventilation.
Cui, K., Xia, Y., Patnaik, A., Salivara, A., Lowenstein, E.D., Isik, E.G., Knorz, A.L., Airaghi, L., Crotti, M., Garratt, A.N., Meng, F., Schmitz, D., Studer, M., Rijli, F.M., Nothwang, H.G., Rost, B.R., Strauß, U. and Hernandez-Miranda, L.R.
Science Advances 10
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21 June 2024
Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2.
Desiderio, S., Schwaller, F., Tartour, K., Padmanabhan, K., Lewin, G.R., Carroll, P. and Marmigere, F.
eLife 12
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22 February 2024
Towards standardizing nomenclature in Huntington's disease research.
DiFiglia, M., Leavitt, B.R., Macdonald, D. and Thompson, L.M.
Journal of Huntington's disease 13
(2): 119-131.
2 July 2024
Simultaneous lung cell and nucleus segmentation from labelled versus unlabelled human lung DIC images.
Dohmen, M., Mittermaier, M., Rumberger, J.L., Yang, L.L., Gruber, A.D., Toennies, M., Hippenstiel, S., Kainmueller, D. and Hocke, A.C.
In: 2024 IEEE International Symposium on Biomedical Imaging (ISBI), 27-30 May 2024, Athens, Greece.
22 August 2024
Time to disability milestones and annualized relapse rates in NMOSD and MOGAD.
Duchow, A., Bellmann-Strobl, J., Friede, T., Aktas, O., Angstwurm, K., Ayzenberg, I., Berthele, A., Dawin, E., Engels, D., Fischer, K., Flaskamp, M., Giglhuber, K., Grothe, M., Havla, J., Hümmert, M.W., Jarius, S., Kaste, M., Kern, P., Kleiter, I., Klotz, L., Korporal-Kuhnke, M., Kraemer, M., Krumbholz, M., Kümpfel, T., Lohmann, L., Ringelstein, M., Rommer, P., Schindler, P., Schubert, C., Schwake, C., Senel, M., Bergh, F.T., Tkachenko, D., Tumami, H., Trebst, C., Vardakas, I., Walter, A., Warnke, C., Weber, M.S., Wickel, J., Wildemann, B., Winkelmann, A., Paul, F., Stellmann, J.P. and Häußler, V.
Annals of Neurology 95
(4): 720-732.
April 2024
Social play behavior is driven by glycine-dependent mechanisms.
Dvorzhak, A., Brecht, M. and Schmitz, D.
Current Biology 34
(16): 3654-3664.e6.
19 August 2024
Relapse-independent disease activity in neuromyelitis optica spectrum disorder: a systematic review.
Etemadifar, M., Alaei, S.A., Akaishi, T., Salari, M., Norouzi, M., Samadzadeh, S. and Paul, F.
Multiple Sclerosis and Related Disorders 90
: 105843.
October 2024
Touch inhibits cold: non-contact cooling reveals a novel thermotactile gating mechanism.
Ezquerra-Romano, I., Chowdhury, M. and Haggard, P.
bioRxiv
: 2024.08.06.606653.
8 August 2024
Treatment switches of disease-modifying therapies in people with multiple sclerosis: long-term experience from the German MS Registry.
Frahm, N., Ellenberger, D., Stahmann, A., Fneish, F., Lüftenegger, D., Salmen, H.C., Schirduan, K., Schaak, T.P.A., Flachenecker, P., Kleinschnitz, C., Paul, F., Krefting, D., Zettl, U.K., Peters, M. and Warnke, C.
Therapeutic Advances in Neurological Disorders 17
: 17562864241239740.
2024
Protocol to characterize immune cell subpopulations in cerebrospinal fluid of patients with neuroinflammatory diseases using mass cytometry.
Gallaccio, G., Wang, M., Schlickeiser, S., Kunkel, D., Böttcher, C. and Fernández-Zapata, C.
STAR Protocols 5
(2): 103038.
27 April 2024
Cell-mediated exon skipping normalizes dystrophin expression and muscle function in a new mouse model of Duchenne Muscular Dystrophy.
Galli, F., Bragg, L., Rossi, M., Proietti, D., Perani, L., Bacigaluppi, M., Tonlorenzi, R., Sibanda, T., Caffarini, M., Talapatra, A., Santoleri, S., Meregalli, M., Bano-Otalora, B., Bigot, A., Bozzoni, I., Bonini, C., Mouly, V., Torrente, Y. and Cossu, G.
EMBO Molecular Medicine 16
(4): 927-944.
15 April 2024
Serum proteomics distinguish subtypes of NMO spectrum disorder and MOG antibody-associated disease and highlight effects of B-cell depletion.
Gawde, S., Siebert, N., Ruprecht, K., Kumar, G., Ko, R.M., Massey, K., Guthridge, J.M., Mao-Draayer, Y., Schindler, P., Hastermann, M., Pardo, G., Paul, F. and Axtell, R.C.
Neurology Neuroimmunology & Neuroinflammation 11
(4): e200268.
July 2024
The influence of MOGAD on diagnosis of multiple sclerosis using MRI.
Geraldes, R., Arrambide, G., Banwell, B., Rovira, À., Cortese, R., Lassmann, H., Messina, S., Rocca, M.A., Waters, P., Chard, D., Gasperini, C., Hacohen, Y., Mariano, R., Paul, F., DeLuca, G.C., Enzinger, C., Kappos, L., Leite, M.I., Sastre-Garriga, J., Yousry, T., Ciccarelli, O., Filippi, M., Barkhof, F. and Palace, J.
Nature Reviews Neurology 20
(10): 620-635.
October 2024
The paradigm change from reactive medical services to 3PM in ischemic stroke: a holistic approach utilising tear fluid multi-omics, mitochondria as a vital biosensor and AI-based multi-professional data interpretation.
Golubnitschaja, O., Polivka, J., Potuznik, P., Pesta, M., Stetkarova, I., Mazurakova, A., Lackova, L., Kubatka, P., Kropp, M., Thumann, G., Erb, C., Fröhlich, H., Wang, W., Baban, B., Kapalla, M., Shapira, N., Richter, K., Karabatsiakis, A., Smokovski, I., Schmeel, L.C., Gkika, E., Paul, F., Parini, P. and Polivka, J.
EPMA Journal 15
(1): 1-23.
March 2024
Impact of sex on clinical outcome in early multiple sclerosis.
Gottwald, N.S., Asseyer, S., Chien, C., Brasanac, J., Nauman, A.T., Rust, R., Schmitz-Hübsch, T., Bellmann-Strobl, J., Ruprecht, K., Paul, F., Regitz-Zagrosek, V., Gold, S.M. and Sperber, P.S.
Multiple Sclerosis and Related Disorders 88
: 105749.
August 2024
Extracellular matrix remodeling in atopic dermatitis harnesses the onset of an asthmatic phenotype and is a potential contributor to the atopic march.
Graff, P., Woerz, D., Wilzopolski, J., Voss, A., Sarrazin, J., Blimkie, T.M., Weiner, J., Kershaw, O., Panwar, P., Hackett, T., Lau, S., Brömme, D., Beule, D., Lee, Y.A., Hancock, R.E.W., Gruber, A.D., Bäumer, W. and Hedtrich, S.
Journal of Investigative Dermatology 144
(5): 1010-1021.
May 2024
CoNIC Challenge: Pushing the frontiers of nuclear detection, segmentation, classification and counting.
Graham, S., Vu, Q.D., Jahanifar, M., Weigert, M., Schmidt, U., Zhang, W., Zhang, J., Yang, S., Xiang, J., Wang, X., Rumberger, J.L., Baumann, E., Hirsch, P., Liu, L., Hong, C., Aviles-Rivero, A.I., Jain, A., Ahn, H., Hong, Y., Azzuni, H., Xu, M., Yaqub, M., Blache, M.C., Piégu, B., Vernay, B., Scherr, T., Böhland, M., Löffler, K., Li, J., Ying, W., Wang, C., Snead, D., Raza, S.E.A., Minhas, F. and Rajpoot, N.M.
Medical Image Analysis 92
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February 2024
Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories.
Gross, C.C., Schulte-Mecklenbeck, A., Steinberg, O.V., Wirth, T., Lauks, S., Bittner, S., Schindler, P., Baranzini, S.E., Groppa, S., Bellmann-Strobl, J., Bünger, N., Chien, C., Dawin, E., Eveslage, M., Fleischer, V., Gonzalez-Escamilla, G., Gisevius, B., Haas, J., Kerschensteiner, M., Kirstein, L., Korsukewitz, C., Lohmann, L., Lünemann, J.D., Luessi, F., Meyer Zu Hörste, G., Motte, J., Ruck, T., Ruprecht, K., Schwab, N., Steffen, F., Meuth, S.G., Paul, F., Wildemann, B., Kümpfel, T., Gold, R., Hahn, T., Zipp, F., Klotz, L. and Wiendl, H.
Science Translational Medicine 16
(740): eade8560.
March 2024
Gamma oscillation plasticity is mediated via parvalbumin interneurons.
Hadler, M.D., Tzilivaki, A., Schmitz, D., Alle, H. and Geiger, J.R.P.
Science Advances 10
(5): eadj7427.
2 February 2024
The T1-weighted/T2-weighted ratio as a biomarker of anti-NMDA receptor encephalitis.
Hartung, T.J., Cooper, G., Jünger, V., Komnenić, D., Ryan, L., Heine, J., Chien, C., Paul, F., Prüss, H. and Finke, C.
Journal of Neurology Neurosurgery and Psychiatry 95
(4): 366-373.
13 March 2024
Mutations in CLCN6 as a novel genetic cause of neuronal ceroid lipofuscinosis in patients and a murine model.
He, H., Cao, X., He, F., Zhang, W., Wang, X., Peng, P., Xie, C., Yin, F., Li, D., Li, J., Wang, M., Klüssendorf, M., Jentsch, T.J., Stauber, T. and Peng, J.
Annals of Neurology 96
(3): 608-624.
September 2024
Hippocampal hub failure is linked to long-term memory impairment in anti-NMDA-receptor encephalitis: insights from structural connectome graph theoretical network analysis.
Hechler, A., Kuchling, J., Müller-Jensen, L., Klag, J., Paul, F., Prüss, H. and Finke, C.
Journal of Neurology 271
(9): 5886-5898.
September 2024
Preferences, adherence, and satisfaction: three years of treatment experiences of people with multiple sclerosis.
Hoffmann, O., Paul, F., Haase, R., Kern, R. and Ziemssen, T.
Patient preference and adherence 18
: 455-466.
22 February 2024
Improving clinical documentation of rare neuromuscular diseases: development of a standardised information model.
Hübner, M., Nyoungui, E., Gazzero, E., Hassoun, L., Zschüntzsch, J., Krefting, D., Schepers, J. and Röttgerd, R.
Studies in Health Technology and Informatics 316
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22 August 2024
Quantitative gait and balance outcomes for ataxia trials: consensus recommendations by the Ataxia Global Initiative Working Group on Digital-Motor Biomarkers.
Ilg, W., Milne, S., Schmitz-Hübsch, T., Alcock, L., Beichert, L., Bertini, E., Mohamed Ibrahim, N., Dawes, H., Gomez, C.M., Hanagasi, H., Kinnunen, K.M., Minnerop, M., Németh, A.H., Newman, J., Ng, Y.S., Rentz, C., Samanci, B., Shah, V.V., Summa, S., Vasco, G., McNames, J. and Horak, F.B.
Cerebellum 23
(4): 1566-1592.
August 2024
Image processing and analysis of light sheet microscopy data.
Jain, A., Ulman, V., Krumnikl, M., Pietzsch, T., Preibisch, S. and Tomančák, P.
In:
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Wiley‐VCH GmbH, Weinheim, Germany, 203-229.
ISBN 9783527341351
18 March 2024
Improving the sensitivity of myelin oligodendrocyte glycoprotein-antibody testing: exclusive or predominant MOG-IgG3 seropositivity - a potential diagnostic pitfall in patients with MOG-EM/MOGAD.
Jarius, S., Ringelstein, M., Schanda, K., Ruprecht, K., Korporal-Kuhnke, M., Viehöver, A., Hümmert, M.W., Schindler, P., Endmayr, V., Gastaldi, M., Trebst, C., Franciotta, D., Aktas, O., Höftberger, R., Haas, J., Komorowski, L., Paul, F., Reindl, M. and Wildemann, B.
Journal of Neurology 271
(7): 4660-4671.
July 2024
Immediate reuse of patch-clamp pipettes after ultrasonic cleaning.
Jehasse, K., Jouhanneau, J.S., Wetz, S., Schwedt, A., Poulet, J.F.A., Neumann-Raizel, P. and Kampa, B.M.
Scientific Reports 14
(1): 1660.
18 January 2024
Multiscale networks in multiple sclerosis.
Kennedy, K.E., Kerlero de Rosbo, N., Uccelli, A., Cellerino, M., Ivaldi, F., Contini, P., De Palma, R., Harbo, H.F., Berge, T., Bos, S.D., Høgestøl, E.A., Brune-Ingebretsen, S., de Rodez Benavent, S.A., Paul, F., Brandt, A.U., Bäcker-Koduah, P., Behrens, J., Kuchling, J., Asseyer, S., Scheel, M., Chien, C., Zimmermann, H., Motamedi, S., Kauer-Bonin, J., Saez-Rodriguez, J., Rinas, M., Alexopoulos, L.G., Andorra, M., Llufriu, S., Saiz, A., Blanco, Y., Martinez-Heras, E., Solana, E., Pulido-Valdeolivas, I., Martinez-Lapiscina, E.H., Garcia-Ojalvo, J. and Villoslada, P.
PLoS Computational Biology 20
(2): e1010980.
February 2024
Rudolf Virchow and the discovery of the Müller cell.
Kettenmann, H.
Graefes Archive for Clinical and Experimental Ophthalmology
5 September 2024
(In Press)
Application of the international criteria for optic neuritis in the Acute Optic Neuritis Network.
Klyscz, P., Asseyer, S., Alonso, R., Bereuter, C., Bialer, O., Bick, A., Carta, S., Chen, J.J., Cohen, L., Cohen-Tayar, Y., Contentti, E.C., Dale, R.C., Flanagan, E.P., Gernert, J.A., Haas, J., Havla, J., Heesen, C., Hellmann, M., Levin, N., Lopez, P., Lotan, I., Luis, M.B., Mariotto, S., Mayer, C., Vergara, A.J.M., Ocampo, C., Ochoa, S., Oertel, F.C., Olszewska, M., Uribe, J.L.P., Sastre-Garriga, J., Scocco, D., Ramanathan, S., Rattanathamsakul, N., Shi, F.D., Shifa, J., Simantov, I., Siritho, S., Tiosano, A., Tisavipat, N., Torres, I., Dembinsky, A.V., Vidal-Jordana, A., Wilf-Yarkoni, A., Wu, Ti, Zamir, S., Zarco, L.A., Zimmermann, H.G., Petzold, A., Paul, F. and Stiebel-Kalish, H.
Annals of Clinical and Translational Neurology
4 August 2024
(In Press)
LRRC8/VRAC volume-regulated anion channels are crucial for hearing.
Knecht, D.A., Zeziulia, M., Bhavsar, M., Puchkov, D., Maier, H. and Jentsch, T.J.
Journal of Biological Chemistry 300
(7): 107436.
July 2024
Superficial white matter integrity in neuromyelitis optica spectrum disorder and multiple sclerosis.
Komnenić, D., Phillips, O.R., Joshi, S.H., Chien, C., Schmitz-Hübsch, T., Asseyer, S., Paul, F. and Finke, C.
Multiple Sclerosis Journal Experimental Translational and Clinical 10
(1): 20552173231226107.
2024
Membrane properties and coupling of macroglia in the optic nerve.
Kompier, N., Semtner, M., Walter, S., Kakabadze, N., Steinhäuser, C., Nolte, C. and Kettenmann, H.
Current Research in Neurobiology 7
: 100137.
21 August 2024
Diverse modulatory effects of bibenzyls from Dendrobium species on human immune cell responses under inflammatory conditions.
Kongkatitham, V., Dehlinger, A., Chaotham, C., Likhitwitayawuid, K., Böttcher, C. and Sritularak, B.
PLoS ONE 19
(2): e0292366.
1 February 2024
Molecular and cellular mechanisms of motor circuit development.
Kratsios, P., Zampieri, N., Carrillo, R., Mizumoto, K., Sweeney, L.B. and Philippidou, P.
Journal of Neuroscience 44
(40): e1238242024.
2 October 2024
Gait Variability as a Potential motor marker of cerebellar disease—relationship between variability of stride, arm swing and trunk movements, and walking speed.
Kroneberg, D., Nümann, A., Minnerop, M., Rönnefarth, M., Endres, M., Kühn, A.A., Paul, F., Doss, S., Solbrig, S., Elshehabi, M., Maetzler, W. and Schmitz-Hübsch, T.
Sensors 24
(11): 3476.
1 June 2024
Evolution of retinal degeneration and prediction of disease activity in relapsing and progressive multiple sclerosis.
Krämer, J., Balloff, C., Weise, M., Koska, V., Uthmeier, Y., Esderts, I., Nguyen-Minh, M., Zimmerhof, M., Hartmann, A., Dietrich, M., Ingwersen, J., Lee, J.I., Havla, J., Kümpfel, T., Kerschensteiner, M., Häußler, V., Heesen, C., Stellmann, J.P., Zimmermann, H.G., Oertel, F.C., Ringelstein, M., Brandt, A.U., Paul, F., Aktas, O., Hartung, H.P., Wiendl, H., Meuth, S.G. and Albrecht, P.
Nature Communications 15
(1): 5243.
19 June 2024
Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part II: Attack therapy and long-term management.
Kümpfel, T., Giglhuber, K., Aktas, O., Ayzenberg, I., Bellmann-Strobl, J., Häußler, V., Havla, J., Hellwig, K., Hümmert, M.W., Jarius, S., Kleiter, I., Klotz, L., Krumbholz, M., Paul, F., Ringelstein, M., Ruprecht, K., Senel, M., Stellmann, J.P., Bergh, F.T., Trebst, C., Tumani, H., Warnke, C., Wildemann, B. and Berthele, A.
Journal of Neurology 271
(1): 141-176.
January 2024
An exploratory research report on brain mineralization in postoperative delirium and cognitive decline.
Lammers-Lietz, F., Borchers, F., Feinkohl, I., Hetzer, S., Kanar, C., Konietschke, F., Lachmann, G., Chien, C., Spies, C., Winterer, G., Zaborszky, L., Zacharias, N. and Paul, F.
European Journal of Neuroscience 59
(10): 2646-2664.
May 2024
Interactions of optic radiation lesions with retinal and brain atrophy in early multiple sclerosis.
Lin, T.Y., Chien, C., Kuchling, J., Asseyer, S., Motamedi, S., Bellmann-Strobl, J., Schmitz-Hübsch, T., Ruprecht, K., Brandt, A.U., Zimmermann, H.G. and Paul, F.
Annals of Clinical and Translational Neurology 11
(1): 45-56.
January 2024
Individual prognostication of disease activity and disability worsening in multiple sclerosis with retinal layer thickness z scores.
Lin, T.Y., Motamedi, S., Asseyer, S., Chien, C., Saidha, S., Calabresi, P.A., Fitzgerald, K.C., Samadzadeh, S., Villoslada, P., Llufriu, S., Green, A.J., Preiningerova, J.L., Petzold, A., Leocani, L., Garcia-Martin, E., Oreja-Guevara, C., Outteryck, O., Vermersch, P., Balcer, L.J., Kenney, R., Albrecht, P., Aktas, O., Costello, F., Frederiksen, J., Uccelli, A., Cellerino, M., Frohman, E.M., Frohman, T.C., Bellmann-Strobl, J., Schmitz-Hübsch, T., Ruprecht, K., Brandt, A.U., Zimmermann, H.G. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 11
(5): e200269.
September 2024
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Lisowski, P., Lickfett, S., Rybak-Wolf, A., Menacho, C., Le, S., Pentimalli, T.M., Notopoulou, S., Dykstra, W., Oehler, D., López-Calcerrada, S., Mlody, B., Otto, M., Wu, H., Richter, Y., Roth, P., Anand, R., Kulka, L.A.M., Meierhofer, D., Glazar, P., Legnini, I., Telugu, N.S., Hahn, T., Neuendorf, N., Miller, D.C., Böddrich, A., Polzin, A., Mayatepek, E., Diecke, S., Olzscha, H., Kirstein, J., Ugalde, C., Petrakis, S., Cambridge, S., Rajewsky, N., Kühn, R., Wanker, E.E., Priller, J., Metzger, J.J. and Prigione, A.
Nature Communications 15
(1): 7027.
22 August 2024
Molecular characterization of nodose ganglia development reveals a novel population of Phox2b+ glial progenitors in mice.
Lowenstein, E.D., Misios, A., Buchert, S. and Ruffault, P.L.
Journal of Neuroscience 44
(28): e1441232024.
10 July 2024
Canonical and non-canonical integrin-based adhesions dynamically interconvert.
Lukas, F., Matthaeus, C., López-Hernández, T., Lahmann, I., Schultz, N., Lehmann, M., Puchkov, D., Pielage, J., Haucke, V. and Maritzen, T.
Nature Communications 15
(1): 2093.
7 March 2024
Metrics reloaded: recommendations for image analysis validation.
Maier-Hein, L., Reinke, A., Godau, P., Tizabi, M.D., Buettner, F., Christodoulou, E., Glocker, B., Isensee, F., Kleesiek, J., Kozubek, M., Reyes, M., Riegler, M.A., Wiesenfarth, M., Kavur, A.E., Sudre, C.H., Baumgartner, M., Eisenmann, M., Heckmann-Nötzel, D., Rädsch, T., Acion, L., Antonelli, M., Arbel, T., Bakas, S., Benis, A., Blaschko, M.B., Cardoso, M.J., Cheplygina, V., Cimini, B.A., Collins, G.S., Farahani, K., Ferrer, L., Galdran, A., van Ginneken, B., Haase, R., Hashimoto, D.A., Hoffman, M.M., Huisman, M., Jannin, P., Kahn, C.E., Kainmueller, D., Kainz, B., Karargyris, A., Karthikesalingam, A., Kofler, F., Kopp-Schneider, A., Kreshuk, A., Kurc, T., Landman, B.A., Litjens, G., Madani, A., Maier-Hein, K., Martel, A.L., Mattson, P., Meijering, E., Menze, B., Moons, K.G.M., Müller, H., Nichyporuk, B., Nickel, F., Petersen, J., Rajpoot, N., Rieke, N., Saez-Rodriguez, J., Sánchez, C.I., Shetty, S., van Smeden, M., Summers, R.M., Taha, A.A., Tiulpin, A., Tsaftaris, S.A., Van Calster, B., Varoquaux, G. and Jäger, P.F.
Nature Methods 21
(2): 195-212.
12 February 2024
Canonical and non-canonical localization of tight junction proteins during early murine cranial development.
Mak, S. and Hammes, A.
International Journal of Molecular Sciences 25
(3): 1426.
24 January 2024
Differences in discounting behavior and brain responses for food and money reward.
Markman, M., Saruco, E., Al-Bas, S., Wang, B.A., Rose, J., Ohla, K., Xue Li Lim, S., Schicker, D., Freiherr, J., Weygandt, M., Rramani, Q., Weber, B., Schultz, J. and Pleger, B.
eNeuro 11
(4): ENEURO.0153-23.2024.
April 2024
Microglia undergo molecular and functional adaptations to dark and light phases in male laboratory mice.
Mattei, D., Ivanov, A., Hammer, J., Ugursu, B., Schalbetter, S., Richetto, J., Weber-Stadlbauer, U., Mueller, F., Scarborough, J., Wolf, S.A., Kettenmann, H., Wollscheid, B., Beule, D. and Meyer, U.
Brain, Behavior and Immunity 210
: 571-583.
August 2024
Magnetic resonance elastography in a nutshell: Tomographic imaging of soft tissue viscoelasticity for detecting and staging disease with a focus on inflammation.
Meyer, T., Castelein, J., Schattenfroh, J., Morr, A.S., Vieira da Silva, R., Tzschätzsch, H., Reiter, R., Guo, J. and Sack, I.
Progress in Nuclear Magnetic Resonance Spectroscopy 144-145
: 1-14.
November 2024
Body mass, neuro-hormonal stress processing, and disease activity in lean to obese people with multiple sclerosis.
Meyer-Arndt, L., Brasanac, J., Gamradt, S., Bellmann-Strobl, J., Maurer, L., Mai, K., Steward, T., Spranger, J., Schmitz-Hübsch, T., Paul, F., Gold, S.M. and Weygandt, M.
Journal of Neurology 271
(4): 1584-1598.
April 2024
Oligodendrocyte-derived LGI3 and its receptor ADAM23 organize juxtaparanodal Kv1 channel clustering for short-term synaptic plasticity.
Miyazaki, Y., Otsuka, T., Yamagata, Y., Endo, T., Sanbo, M., Sano, H., Kobayashi, K., Inahashi, H., Kornau, H.C., Schmitz, D., Prüss, H., Meijer, D., Hirabayashi, M., Fukata, Y. and Fukata, M.
Cell Reports 43
(1): 113634.
23 January 2024
Natural proteome diversity links aneuploidy tolerance to protein turnover.
Muenzner, J., Trébulle, P., Agostini, F., Zauber, H., Messner, C.B., Steger, M., Kilian, C., Lau, K., Barthel, N., Lehmann, A., Textoris-Taube, K., Caudal, E., Egger, A.S., Amari, F., De Chiara, M., Demichev, V., Gossmann, T.I., Mülleder, M., Liti, G., Schacherer, J., Selbach, M., Berman, J. and Ralser, M.
Nature 630
(8015): 149-157.
6 June 2024
A new era in neuromuscular junction research: current advances in self-organized and assembled in vitro models.
Nebol, A. and Gouti, M.
Current Opinion in Genetics & Development 87
: 102229.
August 2024
Greater within- and between-day instability is associated with worse anxiety and depression symptoms.
Nexha, A., Pilz, L.K., Oliveira, M.A.B., Xavier, N.B., Borges, R.B., Frey, B.N. and Hidalgo, M.P.L.
Journal of Affective Disorders 326
: 215-223.
1 July 2024
Anti-aquaporin-4 immune complex stimulates complement-dependent Th17 cytokine release in neuromyelitis optica spectrum disorders.
Nishiyama, S., Seok, J.M., Wright, A.E., Lotan, I., Mikami, T., Drosu, N.C., Bobrowski-Khoury, N., Anderson, M.R., Bilodeau, P.A., Schindler, P., Paul, F., Aoki, M., Yeaman, M.R. and Levy, M.
Scientific Reports 14
(1): 3146.
7 February 2024
Evaluation of machine learning-based classification of clinical impairment and prediction of clinical worsening in multiple sclerosis.
Noteboom, S., Seiler, M., Chien, C., Rane, R.P., Barkhof, F., Strijbis, E.M.M., Paul, F., Schoonheim, M.M. and Ritter, K.
Journal of Neurology 271
(8): 5577-5589.
August 2024
Scientific commentary on: “Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer’s disease and primary tauopathies”.
Oertel, F.C., Casillas, D., Cobigo, Y., Condor Montes, S., Heuer, H.W., Chapman, M., Beaudry-Richard, A., Reinsberg, H., Abdelhak, A., Cordano, C., Boeve, B.F., Dickerson, B.C., Grossman, M., Huey, E., Irwin, D.J., Litvan, I., Pantelyat, A., Tartaglia, M.C., Vandevrede, L., Boxer, A. and Green, A.J.
Acta Neuropathologica 147
(1): 30.
3 February 2024
Retinal changes in double-antibody seronegative neuromyelitis optica spectrum disorders.
Oertel, F.C., Zimmermann, H.G., Motamedi, S., Bereuter, C., Manthey, L.M., Ashtari, F., Kafieh, R., Dehghani, A., Pourazizi, M., Pandit, L., D'Cunha, A., Aktas, O., Albrecht, P., Ringelstein, M., Martinez-Lapiscina, E.H., Sanchez Dalmau, B.F., Villoslada, P., Asgari, N., Marignier, R., Cobo-Calvo, A., Leocani, L., Pisa, M., Radaelli, M., Palace, J., Roca-Fernandez, A., Leite, M.I.S., Sharma, S., De Seze, J., Senger, T., Yeaman, M.R., Smith, T.J., Cook, L.J., Brandt, A.U. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 11
(5): e200273.
September 2024
Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception.
Ojeda-Alonso, J., Calvo-Enrique, L., Paricio-Montesinos, R., Kumar, R., Zhang, M.D., Poulet, J.F.A., Ernfors, P. and Lewin, G.R.
Nature Communications 15
(1): 898.
6 February 2024
Impaired hand grip strength correlates with greater disability and symptom severity in post-COVID myalgic encephalomyelitis/chronic fatigue syndrome.
Paffrath, A., Kim, L., Kedor, C., Stein, E., Rust, R., Freitag, H., Hoppmann, U., Hanitsch, L.G., Bellmann-Strobl, J., Wittke, K., Scheibenbogen, C. and Sotzny, F.
Journal of Clinical Medicine 13
(7): 2153.
8 April 2024
Rapid differentiation of MOGAD and MS after a single optic neuritis.
Pakeerathan, T., Havla, J., Schwake, C., Salmen, A., Ringelstein, M., Aktas, O., Weise, M., Gernert, J.A., Kornek, B., Bsteh, G., Pröbstel, A.K., Papadopoulou, A., Kulsvehagen, L., Ayroza Galvão Ribeiro Gomes, A.B., Cerdá-Fuertes, N., Oertel, F.C., Duchow, A.S., Paul, F., Stellmann, J.P., Stolowy, N., Hellwig, K., Schneider-Gold, C., Kümpfel, T., Gold, R., Albrecht, P. and Ayzenberg, I.
Journal of Neurology
9 September 2024
(In Press)
Cognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease: a prospective, longitudinal, multicentre study of 113 patients (CogniMOG-Study).
Passoke, S., Stern, C., Häußler, V., Kümpfel, T., Havla, J., Engels, D., Jarius, S., Wildemann, B., Korporal-Kuhnke, M., Senel, M., Stellmann, J.P., Warnke, C., Grothe, M., Schülke, R., Gingele, S., Kretschmer, J.R., Klotz, L., Walter, A., Then Bergh, F., Aktas, O., Ringelstein, M., Ayzenberg, I., Schwake, C., Kleiter, I., Sperber, P.S., Rust, R., Schindler, P., Bellmann-Strobl, J., Paul, F., Kopp, B., Trebst, C. and Hümmert, M.W.
Journal of Neurology Neurosurgery and Psychiatry
30 July 2024
(In Press)
Multiple Sklerose.
Paul, F. and Seifert, R.
In:
Arzneiverordnungs-Report 2023.
Springer, Berlin, Heidelberg, Berlin, Heidelberg, Germany, 531-552.
ISBN 978-3-662-68371-2
22 February 2024
The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte coupling in mice.
Pelz, L., Dossou, L., Kompier, N., Jüttner, R., Siemonsmeier, G., Meyer, N., Lowenstein, E.D., Lahmann, I., Kettenmann, H., Birchmeier, C. and Rathjen, F.G.
eNeuro
22 February 2024
(In Press)
Directed and acyclic synaptic connectivity in the human layer 2-3 cortical microcircuit.
Peng, Y., Bjelde, A., Aceituno, P.V., Mittermaier, F.X., Planert, H., Grosser, S., Onken, J., Faust, K., Kalbhenn, T., Simon, M., Radbruch, H., Fidzinski, P., Schmitz, D., Alle, H., Holtkamp, M., Vida, I., Grewe, B.F. and Geiger, J.R.P.
Science 384
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26 April 2024
SARA captures disparate progression and responsiveness in spinocerebellar ataxias.
Petit, E., Schmitz-Hübsch, T., Coarelli, G., Jacobi, H., Heinzmann, A., Figueroa, K.P., Perlman, S.L., Gomez, C.M., Wilmot, G.R., Schmahmann, J.D., Ying, S.H., Zesiewicz, T.A., Paulson, H.L., Shakkottai, V.G., Bushara, K.O., Kuo, S.H., Geschwind, M.D., Xia, G., Pulst, S.M., Subramony, S.H., Ewenczyk, C., Brice, A., Durr, A., Klockgether, T., Ashizawa, T. and Tezenas du Montcel, S.
Journal of Neurology 271
(7): 3743-3753.
July 2024
Gain-of-function variants in CLCN7 cause hypopigmentation and lysosomal storage disease.
Polovitskaya, M.M., Rana, T., Ullrich, K., Murko, S., Bierhals, T., Vogt, G., Stauber, T., Kubisch, C., Santer, R. and Jentsch, T.J.
Journal of Biological Chemistry 300
(7): 107437.
July 2024
A future of AI-driven personalized care for people with multiple sclerosis.
Praet, J., Anderhalten, L., Comi, G., Horakova, D., Ziemssen, T., Vermersch, P., Lukas, C., van Leemput, K., Steppe, M., Aguilera, C., Kadas, E.M., Bertrand, A., van Rampelbergh, J., de Boer, E., Zingler, V., Smeets, D., Ribbens, A. and Paul, F.
Frontiers in Immunology 15
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19 August 2024
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Radke, J., Meinhardt, J., Aschman, T., Chua, R.L., Farztdinov, V., Lukassen, S., Ten, F.W., Friebel, E., Ishaque, N., Franz, J., Huhle, V.H., Mothes, R., Peters, K., Thomas, C., Schneeberger, S., Schumann, E., Kawelke, L., Jünger, J., Horst, V., Streit, S., von Manitius, R., Körtvélyessy, P., Vielhaber, S., Reinhold, D., Hauser, A.E., Osterloh, A., Enghard, P., Ihlow, J., Elezkurtaj, S., Horst, D., Kurth, F., Müller, M.A., Gassen, N.C., Melchert, J., Jechow, K., Timmermann, B., Fernandez-Zapata, C., Böttcher, C., Stenzel, W., Krüger, E., Landthaler, M., Wyler, E., Corman, V., Stadelmann, C., Ralser, M., Eils, R., Heppner, F.L., Mülleder, M., Conrad, C. and Radbruch, H.
Nature Neuroscience 27
(3): 409-420.
March 2024
Understanding metric-related pitfalls in image analysis validation.
Reinke, A., Tizabi, M.D., Baumgartner, M., Eisenmann, M., Heckmann-Nötzel, D., Kavur, A.E., Rädsch, T., Sudre, C.H., Acion, L., Antonelli, M., Arbel, T., Bakas, S., Benis, A., Buettner, F., Cardoso, M.J., Cheplygina, V., Chen, J., Christodoulou, E., Cimini, B.A., Farahani, K., Ferrer, L., Galdran, A., van Ginneken, B., Glocker, B., Godau, P., Hashimoto, D.A., Hoffman, M.M., Huisman, M., Isensee, F., Jannin, P., Kahn, C.E., Kainmueller, D., Kainz, B., Karargyris, A., Kleesiek, J., Kofler, F., Kooi, T., Kopp-Schneider, A., Kozubek, M., Kreshuk, A., Kurc, T., Landman, B.A., Litjens, G., Madani, A., Maier-Hein, K., Martel, A.L., Meijering, E., Menze, B., Moons, K.G.M., Müller, H., Nichyporuk, B., Nickel, F., Petersen, J., Rafelski, S.M., Rajpoot, N., Reyes, M., Riegler, M.A., Rieke, N., Saez-Rodriguez, J., Sánchez, C.I., Shetty, S., Summers, R.M., Taha, A.A., Tiulpin, A., Tsaftaris, S.A., Van Calster, B., Varoquaux, G., Yaniv, Z.R., Jäger, P.F. and Maier-Hein, L.
Nature Methods 21
(2): 182–194.
February 2024
Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T., Meyer, K., Roske, Y., Uyar, B., Akalin, A., Imami, K., Ishihama, Y., Daumke, O. and Selbach, M.
Nature Communications 15
(1): 3146.
11 April 2024
Autoantigen-specific CD4(+) T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases.
Saggau, C., Bacher, P., Esser, D., Rasa, M., Meise, S., Mohr, N., Kohlstedt, N., Hutloff, A., Schacht, S.S., Dargvainiene, J., Martini, G.R., Stürner, K.H., Schröder, I., Markewitz, R., Hartl, J., Hastermann, M., Duchow, A., Schindler, P., Becker, M., Bautista, C., Gottfreund, J., Walter, J., Polansky, J.K., Yang, M., Naghavian, R., Wendorff, M., Schuster, E.M., Dahl, A., Petzold, A., Reinhardt, S., Franke, A., Wieczorek, M., Henschel, L., Berger, D., Heine, G., Holtsche, M., Häußler, V., Peters, C., Schmidt, E., Fillatreau, S., Busch, D.H., Wandinger, K.P., Schober, K., Martin, R., Paul, F., Leypoldt, F. and Scheffold, A.
Immunity
2 September 2024
(In Press)
Protocol of a prospective multicenter study on comorbidity impact on multiple sclerosis and antibody-mediated diseases of the central nervous system (COMMIT).
Samadzadeh, S., Adnan, R., Berglova, P., Barzegar, M., Debrabant, B., Roikjaer, S.G., Levy, M., Petzold, A., Palace, J., Flanagan, E.P., Mariotto, S., Skou, S.T., Froelich, A., Lotan, I., Messina, S., Geraldes, R., Asseyer, S., Stiebel-Kalish, H., Oertel, F.C., Shaygannejad, V., Sahraian, M.A., Kim, H.J., Bennett, J.L., Böttcher, C., Zimmermann, H.G., Weinshenker, B.G., Paul, F. and Asgari, N.
Frontiers in Immunology 15
: 1380025.
2 July 2024
Structure and function of the hippocampal CA3 module.
Sammons, R.P., Vezir, M., Moreno-Velasquez, L., Cano, G., Orlando, M., Sievers, M., Grasso, E., Metodieva, V.D., Kempter, R., Schmidt, H. and Schmitz, D.
Proceedings of the National Academy of Sciences of the United States of America 121
(6): e2312281120.
6 February 2024
A novel developmental critical period of orexinergic signaling in the primary visual thalamus.
Sanetra, A.M., Jeczmien-Lazur, J.S., Pradel, K., Klich, J.D., Palus-Chramiec, K., Janik, M.E., Bajkacz, S., Izowit, G., Nathan, C., Piggins, H.D., Delogu, A., Belle, M.D.C., Lewandowski, M.H. and Chrobok, L.
iScience 27
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19 July 2024
Multiomic spatial landscape of innate immune cells at human central nervous system borders.
Sankowski, R., Süß, P., Benkendorff, A., Böttcher, C., Fernandez-Zapata, C., Chhatbar, C., Cahueau, J., Monaco, G., Gasull, A.D., Khavaran, A., Grauvogel, J., Scheiwe, C., Shah, M.J., Heiland, D.H., Schnell, O., Markfeld-Erol, F., Kunze, M., Zeiser, R., Priller, J. and Prinz, M.
Nature Medicine 30
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January 2024
Making sense of proprioception.
Santuz, A. and Zampieri, N.
Trends in Genetics 40
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January 2024
Associations of C-reactive protein with depressive symptoms over time after mild to moderate ischemic stroke in the PROSCIS-B cohort.
Schaeff, V.L.K., Sperber, P.S., Piper, S.K., Giesers, N.K., Gertz, K., Heuschmann, P.U., Endres, M. and Liman, T.G.
Journal of Neurology 271
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February 2024
Propagation of sharp wave-ripple activity in the mouse hippocampal CA3 subfield in vitro.
Schieferstein, N., Del Toro, A., Evangelista, R., Imbrosci, B., Swaminathan, A., Schmitz, D., Maier, N. and Kempter, R.
Journal of Physiology
31 August 2024
(In Press)
Longitudinal change of serum NfL as disease activity biomarker candidate in MOGAD: a descriptive cohort study.
Schindler, P., Bellmann-Strobl, J., Kuhle, J., Wildemann, B., Jarius, S., Paul, F. and Ruprecht, K.
Multiple Sclerosis and Related Disorders 88
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August 2024
Inebilizumab for neuromyelitis optica spectrum disorders.
Schindler, P. and Paul, F.
touchREVIEWS in Neurology 20
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2024
Validity constraints for data analysis workflows.
Schintke, F., Belhajjame, K., De Mecquenem, N., Frantz, D., Guarino, V.E., Hilbrich, M., Lehmann, F., Missier, P., Sattler, R., Sparka, J.A., Speckhard, D.T., Stolte, H., Vu, A.D. and Leser, U.
Future Generation Computer Systems 157
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August 2024
Cortical cellular encoding of thermotactile integration.
Schnepel, P., Paricio-Montesinos, R., Ezquerra-Romano, I., Haggard, P. and Poulet, J.F.A.
Current Biology 34
(8): 1718-1730.
22 April 2024
Muscle stiffness indicating mission crew health in space.
Schoenrock, B., Muckelt, P.E., Hastermann, M., Albracht, K., MacGregor, R., Martin, D., Gunga, H.C., Salanova, M., Stokes, M.J., Warner, M.B. and Blottner, D.
Scientific Reports 14
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20 February 2024
TLIMB - a transfer learning framework for image analysis of the brain.
Schulz, M.A., Albrecht, J.P., Yilmaz, A., Koch, A., Kainmüller, D., Leser, U. and Ritter, K.
In: Workshops of the EDBT/ICDT 2024 Joint Conference, EDBT/ICDT-WS 2024, 25-28 March 2024, Paestum, Italy.
25 March 2024
Routing of Kv7.1 to endoplasmic reticulum plasma membrane junctions.
Serrano-Novillo, C., Estadella, I., Navarro-Pérez, M., Oliveras, A., de Benito-Bueno, A., Socuéllamos, P.G., Bosch, M., Coronado, M.J., Sastre, D., Valenzuela, C., Soeller, C. and Felipe, A.
Acta Physiologica 240
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March 2024
Do transformers and CNNs learn different concepts of brain age?
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bioRxiv
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Scale for the assessment and rating of ataxia (SARA):
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Silberbauer, J., Schidl, S., Diermayr, G., Schmitz-Hübsch, T. and Greisberger, A.
Wiener Medizinische Wochenschrift 174
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April 2024
Cortical matrix remodeling as a hallmark of relapsing-remitting neuroinflammation in MR elastography and quantitative MRI.
Silva, R.V., Morr, A.S., Herthum, H., Koch, S.P., Mueller, S., Batzdorf, C.S., Bertalan, G., Meyer, T., Tzschätzsch, H., Kühl, A.A., Boehm-Sturm, P., Braun, J., Scheel, M., Paul, F., Infante-Duarte, C. and Sack, I.
Acta Neuropathologica 147
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4 January 2024
Huntingtin protein–protein interactions: From biology to therapeutic targets.
Silva Ramos, E., Greco, T.M., Cristea, I.M. and Wanker, E.E.
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Central intra-lesional iron deposits as a possible novel imaging marker at 7 Tesla MRI in Susac Syndrome - an exploratory study.
Strunk, D., Sinnecker, T., Kleffner, I., Doerr, J., Ringelstein, M., Gross, C.C., Deuschl, C., Maderwald, S., Quick, H.H., Yamac, E., Wrede, K.H. and Kraemer, M.
BMC Medical Imaging 24
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2 January 2024
Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials.
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EClinicalMedicine 70
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April 2024
Piezo2 voltage-block regulates mechanical pain sensitivity.
Sánchez-Carranza, O., Chakrabarti, S., Kühnemund, J., Schwaller, F., Bégay, V., García-Contreras, J.A., Wang, Lin and Lewin, G.R.
Brain 147
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October 2024
Surface modification of lipid nanoparticles for gene therapy.
Tafech, B., Mohabatpour, F. and Hedtrich, S.
Journal of Gene Medicine 26
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January 2024
Exploring mechanisms of lipid nanoparticle-mucus interactions in healthy and cystic fibrosis conditions.
Tafech, B., Rokhforouz, M.R., Leung, J., Sung, M.M., Lin, P.J., Sin, D.D., Lauster, D., Block, S., Quon, B.S., Tam, Y., Cullis, P., Feng, J.J. and Hedtrich, S.
Advanced Healthcare Materials 13
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17 July 2024
New phenanthrenequinones from Cymbidium ensifolium roots and their anti-inflammatory activity on lipopolysaccharide-activated BV2 microglial cells.
Thant, M.T., Hasriadi, H., Poldorn, P., Jungsuttiwong, S., Rojsitthisak, P., Böttcher, C., Towiwat, P. and Sritularak, B.
RSC Advances 14
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5 September 2024
New phenolic glycosides from Coelogyne fuscescens Lindl. var. brunnea and their cytotoxicity against human breast cancer cells.
Thant, M.T., Bhummaphan, N., Wuttiin, J., Puttipanyalears, C., Chaichompoo, W., Rojsitthisak, P., Punpreuk, Y., Böttcher, C., Likhitwitayawuid, K. and Sritularak, B.
ACS Omega 9
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20 February 2024
AI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor.
Trepte, P., Secker, C., Olivet, J., Blavier, J., Kostova, S., Maseko, S.B., Minia, I., Silva Ramos, E., Cassonnet, P., Golusik, S., Zenkner, M., Beetz, S., Liebich, M.J., Scharek, N., Schutz, A., Sperling, M., Lisurek, M., Wang, Y., Spirohn, K., Hao, T., Calderwood, M.A., Hill, D.E., Landthaler, M., Choi, S.G., Twizere, J.C., Vidal, M. and Wanker, E.E.
Molecular Systems Biology 20
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2 April 2024
KCNQ5 controls perivascular adipose tissue–mediated vasodilation.
Tsvetkov, D., Schleifenbaum, J., Wang, Y., Kassmann, M., Polovitskaya, M.M., Ali, M., Schütze, S., Rothe, M., Luft, F.C., Jentsch, T.J. and Gollasch, M.
Hypertension 81
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March 2024
Modulating the mucosal drug delivery efficiency of polymeric nanogels tuning their redox response and surface charge.
Udabe, J., Muñoz‐Juan, A., Tafech, B., Orellano, M.S., Hedtrich, S., Laromaine, A. and Calderón, M.
Advanced Functional Materials
5 September 2024
(In Press)
Microglial sex differences in innate high anxiety and modulatory effects of minocycline.
Ugursu, B., Sah, A., Sartori, S., Popp, O., Mertins, P., Dunay, I.R., Kettenmann, H., Singewald, N. and Wolf, S.A.
Brain Behavior and Immunity 119
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July 2024
Quantification of microglial engulfment of synaptic material using flow cytometry.
Ugursu, B. and Wolf, S.A.
Journal of Visualized Experiments
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31 May 2024
NMOSD and MOGAD: an evolving disease spectrum.
Uzawa, A., Oertel, F.C., Mori, M., Paul, F. and Kuwabara, S.
Nature Reviews Neurology 20
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October 2024
Simultaneous spectral illumination of microplates for high-throughput optogenetics and photobiology.
Vogt, A., Paulat, R., Parthier, D., Just, V., Szczepek, M., Scheerer, P., Xu, Q., Möglich, A., Schmitz, D., Rost, B.R. and Wenger, N.
Biological Chemistry
23 September 2024
(In Press)
Diagnostic value of inter-eye difference metrics on OCT for myelin oligodendrocyte glycoprotein antibody-associated optic neuritis.
Volpe, G., Jurkute, N., Girafa, G., Zimmermann, H.G., Motamedi, S., Bereuter, C., Pandit, L., D'Cunha, A., Yeaman, M.R., Smith, T.J., Cook, L.J., Brandt, A.U., Paul, F., Petzold, A. and Oertel, F.C.
Neurology Neuroimmunology & Neuroinflammation 11
(6): e200291.
November 2024
Association of neurogranin and BACE1 with clinical cognitive decline in individuals with subjective cognitive decline.
Wang, X., Freiesleben, S.D., Schneider, L.S., Preis, L., Priller, J., Spruth, E.J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Hansen, N., Jessen, F., Rostamzadeh, A., Duzel, E., Glanz, W., Incesoy, E.I., Buerger, K., Janowitz, D., Ewers, M., Perneczky, R., Rauchmann, B.S., Teipel, S.J., Kilimann, I., Goerss, D., Laske, C., Munk, M.H.J., Spottke, A., Roy-Kluth, N., Heneka, M.T., Brosseron, F., Wagner, M., Wolfsgruber, S., Ramirez, A., Kleineidam, L., Stark, M. and Peters, O.
Neurology 103
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22 October 2024
Differentiation between Parkinson’s disease and the parkinsonian subtype of multiple system atrophy using the magnetic resonance T1w/T2w ratio in the middle cerebellar peduncle.
Wang, J., Sugiyama, A., Yokota, H., Hirano, S., Yamamoto, T., Yamanaka, Y., Araki, N., Ito, S., Paul, F. and Kuwabara, S.
Diagnostics 14
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January 2024
Combining Data Independent Acquisition with spike-in SILAC (DIA-SiS) improves proteome coverage and quantification.
Welter, A.S., Gerwien, M., Kerridge, R., Alp, K.M., Mertins, P. and Selbach, M.
Molecular & Cellular Proteomics
: 100839.
11 September 2024
(In Press)
A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits.
Wietek, J., Nozownik, A., Pulin, M., Saraf-Sinik, I., Matosevich, N., Gowrishankar, R., Gat, A., Malan, D., Brown, B.J., Dine, J., Imambocus, B.N., Levy, R., Sauter, K., Litvin, A., Regev, N., Subramaniam, S., Abrera, K., Summarli, D., Goren, E.M., Mizrachi, G., Bitton, E., Benjamin, A., Copits, B.A., Sasse, P., Rost, B.R., Schmitz, D., Bruchas, M.R., Soba, P., Oren-Suissa, M., Nir, Y., Wiegert, J.S. and Yizhar, O.
Nature Methods 21
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July 2024
Clinical characterization and ancillary tests in Susac syndrome: a systematic review.
Wilf-Yarkoni, A., Zmira, O., Tolkovsky, A., Pflantzer, B., Gofrit, S.G., Kleffner, I., Paul, F. and Dörr, J.
Neurology Neuroimmunology & Neuroinflammation 11
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May 2024
Intranasal delivery of low-dose anti-CD124 antibody enhances treatment of chronic rhinosinusitis with nasal polyps.
Wu, J., Jones, N., Chao, P.H., Chan, V., Hohenwarter, L., Wu, A., Bergamo, M., Rodríguez-Rodríguez, C., Saatchi, K., Liang, A., Häfeli, U.O., Tan, Z., Hedtrich, S., Andrew, L.J. and Li, S.D.
Biomaterials 308
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July 2024
Systemic delivery of proteins using novel peptides via the sublingual route.
Wu, J., Jones, N., Hohenwarter, L., Zhao, F., Chan, V., Tan, Z., Carlaw, T., Morin, T., Li, J., Kaur, T., Andrew, L.J., Ross, C.J.D., Hedtrich, S. and Li, S.D.
Journal of Controlled Release 368
: 290-302.
April 2024
Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Yalcin, F., Haneke, H., Efe, I.E., Kuhrt, L.D., Motta, E., Nickl, B., Flüh, C., Synowitz, M., Dzaye, O., Bader, M. and Kettenmann, H.
Acta Neuropathologica Communications 12
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2 April 2024
Model guidance via explanations turns image classifiers into segmentation models.
Yu, X., Franzen, J., Samek, W., Höhne, M.M.C. and Kainmueller, D.
In: Second World Conference, xAI 2024, July 17–19, 2024, Valletta, Malta.
10 July 2024
Effects of a 6-week treadmill training with and without virtual reality on frailty in people with multiple sclerosis: Frailty rehabilitation in multiple sclerosis.
Zanotto, T., Galperin, I., Kumar, D.P., Mirelman, A., Yehezkyahu, S., Regev, K., Karni, A., Schmitz-Hübsch, T., Paul, F., Lynch, S.G., Akinwuntan, A.E., He, J., Troen, B.R., Devos, H., Hausdorff, J.M. and Sosnoff, J.J.
Archives of Physical Medicine and Rehabilitation
26 September 2024
(In Press)
Specific nanoprobe design for MRI: targeting laminin in the blood-brain barrier to follow alteration due to neuroinflammation.
Zapata-Acevedo, J.F., Losada-Barragán, M., Osma, J.F., Cruz, J.C., Reiber, A., Petry, K.G., Caillard, A., Sauldubois, A., Llamosa Pérez, D., Morillo Zárate, A.J., Muñoz, S.B., Daza Moreno, A., Silva, R.V., Infante-Duarte, C., Chamorro-Coral, W., González-Reyes, R.E. and Vargas-Sánchez, K.
PLoS ONE 19
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11 April 2024
The global patient-reported outcomes for multiple sclerosis initiative: bridging the gap between clinical research and care – updates at the 2023 plenary event.
Zaratin, P., Samadzadeh, S., Seferoğlu, M., Ricigliano, V., Dos Santos Silva, J., Tunc, A., Brichetto, G., Coetzee, T., Helme, A., Khan, U., McBurney, R., Peryer, G., Weiland, H., Baneke, P., Battaglia, M.A., Block, V., Capezzuto, L., Carment, L., Cortesi, P.A., Cutter, G., Leocani, L., Hartung, H.P., Hillert, J., Hobart, J., Immonen, K., Kamudoni, P., Middleton, R., Moghames, P., Montalban, X., Peeters, L., Sormani, M.P., van Tonder, S., White, A., Comi, G. and Vermersch, P.
Frontiers in Neurology 15
: 1407257.
2024
Transcriptomic mapping of the 5-HT receptor landscape.
de Filippo, R. and Schmitz, D.
Patterns
: 101048.
29 August 2024
Synthetic surprise as the foundation of the psychedelic experience.
de Filippo, R. and Schmitz, D.
Neuroscience and Biobehavioral Reviews 157
: 105538.
February 2024
Routine regularity during a global pandemic: impact on mental health outcomes and influence of chronotype.
de Sá Couto-Pereira, N., Nexha, A., Boff Borges, R., Amando, G.R., Francisco, A.P., Amaral, F.G., Frey, B.N., Calcagnotto, M.E., Hidalgo, M.P. and Pilz, L.K.
Chronobiology International 41
(3): 456-472.
2024
2023
Neurofilament light chain elevation and disability progression in multiple sclerosis.
Abdelhak, A., Benkert, P., Schaedelin, S., Boscardin, W.J., Cordano, C., Oechtering, J., Ananth, K., Granziera, C., Melie-Garcia, L., Montes, S.C., Beaudry-Richard, A., Achtnichts, L., Oertel, F.C., Lalive, P.H., Leppert, D., Müller, S., Henry, R.G., Pot, C., Matthias, A., Salmen, A., Oksenberg, J.R., Disanto, G., Zecca, C., D’Souza, M., Du Pasquier, R., Bridel, C., Gobbi, C., Kappos, L., Hauser, S.L., Cree, B.A.C., Kuhle, J. and Green, A.J.
JAMA Neurology 80
(12): 1317-1325.
December 2023
Safety and discontinuation rate of dimethyl fumarate (Zadiva®) in patients with multiple sclerosis: an observational retrospective study.
Abolfazli, R., Sahraian, M.A., Tayebi, A., Kafi, H. and Samadzadeh, S.
Journal of Clinical Medicine 12
(15): 4937.
27 July 2023
Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in neuromyelitis optica spectrum disorder.
Aktas, O., Hartung, H.P., Smith, M.A., Rees, W.A., Fujihara, K., Paul, F., Marignier, R., Bennett, J.L., Kim, H.J., Weinshenker, B.G., Pittock, S.J., Wingerchuk, D.M., Cutter, G., She, D., Gunsior, M., Cimbora, D., Katz, E. and Cree, B.A.
Journal of Neurology Neurosurgery and Psychiatry 94
(9): 757-768.
September 2023
Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Alteen, M.G., Deme, J.C., Alvarez, C.P., Loppnau, P., Hutchinson, A., Seitova, A., Chandrasekaran, R., Silva Ramos, E., Secker, C., Alqazzaz, M., Wanker, E.E., Lea, S.M., Arrowsmith, C.H. and Harding, R.J.
Structure 31
(9): 1121-1131.e6.
7 September 2023
Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering.
Andreas, M.N., Boehm, A.K., Tang, P., Moosburner, S., Klein, O., Daneshgar, A., Gaßner, J.M.G.V., Raschzok, N., Haderer, L., Wulsten, D., Rückert, J.C., Spuler, S., Pratschke, J., Sauer, I.M. and Hillebrandt, K.H.
Biomaterials Advances 153
: 213493.
October 2023
Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M., Liman, T.G., Strzelecka, P.M., Kufner, A., Löwe, P., Huo, S., Stein, C.M., Piper, S.K., Tilgner, M., Sperber, P.S., Dimitriou, S., Heuschmann, P., Hablesreiter, R., Harms, C., Bullinger, L., Weber, J.E., Endres, M. and Damm, F.
Blood 141
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16 February 2023
Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles.
Aschman, T., Wyler, E., Baum, O., Hentschel, A., Rust, R., Legler, F., Preusse, C., Meyer-Arndt, L., Büttnerova, I., Förster, A., Cengiz, D., Teixeira Alves, L.G., Schneider, J., Kedor, C., Bellmann-Strobl, J., Sanchin, A., Goebel, H.H., Landthaler, M., Corman, V., Roos, A., Heppner, F.L., Radbruch, H., Paul, F., Scheibenbogen, C., Dengler, N.F. and Stenzel, W.
Acta Neuropathologica Communications 11
(1): 193.
8 December 2023
The Acute Optic Neuritis Network (ACON): study protocol of a non-interventional prospective multicenter study on diagnosis and treatment of acute optic neuritis.
Asseyer, S., Asgari, N., Bennett, J., Bialer, O., Blanco, Y., Bosello, F., Camos-Carreras, A., Carnero Contentti, E., Carta, S., Chen, J., Chien, C., Chomba, M., Dale, R.C., Dalmau, J., Feldmann, K., Flanagan, E.P., Froment Tilikete, C., Garcia-Alfonso, C., Havla, J., Hellmann, M., Kim, H.J., Klyscz, P., Konietschke, F., La Morgia, C., Lana-Peixoto, M., Leite, M.I., Levin, N., Levy, M., Llufriu, S., Lopez, P., Lotan, I., Lugaresi, A., Marignier, R., Mariotto, S., Mollan, S.P., Ocampo, C., Oertel, F.C., Olszewska, M., Palace, J., Pandit, L., Peralta Uribe, J.L., Pittock, S., Ramanathan, S., Rattanathamsakul, N., Saiz, A., Samadzadeh, S., Sanchez-Dalmau, B., Saylor, D., Scheel, M., Schmitz-Hübsch, T., Shifa, J., Siritho, S., Sperber, P.S., Subramanian, P.S., Tiosano, A., Vaknin-Dembinsky, A., Mejia Vergara, A.J., Wilf-Yarkoni, A., Zarco, L.A., Zimmermann, H.G., Paul, F. and Stiebel-Kalish, H.
Frontiers in Neurology 14
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24 February 2023
Immunoglobulin A antibodies against myelin oligodendrocyte glycoprotein in a subgroup of patients with central nervous system demyelination.
Ayroza Galvão Ribeiro Gomes, A.B., Kulsvehagen, L., Lipps, P., Cagol, A., Cerdá-Fuertes, N., Neziraj, T., Flammer, J., Lerner, J., Lecourt, A.C., de Oliveira S Siebenborn, N., Cortese, R., Schaedelin, S., Andreoli Schoeps, V., de Moura Brasil Matos, A., Trombini Mendes, N., Dos Reis Pereira, C., Ribeiro Monteiro, M.L., Dos Apóstolos-Pereira, S.L., Schindler, P., Chien, C., Schwake, C., Schneider, R., Pakeerathan, T., Aktas, O., Fischer, U., Mehling, M., Derfuss, T., Kappos, L., Ayzenberg, I., Ringelstein, M., Paul, F., Callegaro, D., Kuhle, J., Papadopoulou, A., Granziera, C. and Pröbstel, A.K.
JAMA Neurology 80
(9): 989-995.
September 2023
Cephalopod-omics: emerging fields and technologies in cephalopod biology.
Baden, T., Briseño, J., Coffing, G., Cohen-Bodénès, S., Courtney, A., Dickerson, D., Dölen, G., Fiorito, G., Gestal, C., Gustafson, T., Heath-Heckman, E., Hua, Q., Imperadore, P., Kimbara, R., Król, M., Lajbner, Z., Lichilín, N., Macchi, F., McCoy, M.J., Nishiguchi, M.K., Nyholm, S.V., Otjacques, E., Pérez-Ferrer, P.A., Ponte, G., Pungor, J.R., Rogers, T.F., Rosenthal, J.J.C., Rouressol, L., Rubas, N., Sanchez, G., Santos, C.P., Schultz, D.T., Seuntjens, E., Songco-Casey, J.O., Stewart, I.E., Styfhals, R., Tuanapaya, S., Vijayan, N., Weissenbacher, A., Zifcakova, L., Schulz, G., Weertman, W., Simakov, O. and Albertin, C.
Integrative and Comparative Biology 63
(6): 1226-1239.
December 2023
Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria.
Banwell, B., Bennett, J.L., Marignier, R., Kim, H.J., Brilot, F., Flanagan, E.P., Ramanathan, S., Waters, P., Tenembaum, S., Graves, J.S., Chitnis, T., Brandt, A.U., Hemingway, C., Neuteboom, R., Pandit, L., Reindl, M., Saiz, A., Sato, D.K., Rostasy, K., Paul, F., Pittock, S.J., Fujihara, K. and Palace, J.
Lancet Neurology 22
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March 2023
Aberrant adenosine triphosphate release and impairment of P2Y2-Mediated signaling in sarcoglycanopathies.
Benzi, A., Baratto, S., Astigiano, C., Sturla, L., Panicucci, C., Mamchaoui, K., Raffaghello, L., Bruzzone, S., Gazzerro, E. and Bruno, C.
Laboratory Investigation 103
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March 2023
Therapien zum Zellersatz mit adulten Stammzelltypen.
Besser, D., Bönig, H.B., Giebel, B., Klump, H. and Spuler, S.
In:
Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft.
Springer, Berlin, Heidelberg, Germany, 217-232.
ISBN 978-3-662-67908-1
30 December 2023
Regulation of developmental tempo in different vertebrate species.
Birchmeier, C.
Cell Stem Cell 30
(7): 907-908.
6 July 2023
The C-terminus of α-synuclein regulates its dynamic cellular internalization by neurexin 1β.
Birol, M., Douzoglou Muñoz, I.I. and Rhoades, E.
Molecular Biology of the Cell 34
(13): br21.
1 December 2023
Space omics and tissue response in astronaut skeletal muscle after short and long duration missions.
Blottner, D., Moriggi, M., Trautmann, G., Hastermann, M., Capitanio, D., Torretta, E., Block, K., Rittweger, J., Limper, U., Gelfi, C. and Salanova, M.
International Journal of Molecular Sciences 24
(4): 4095.
2 February 2023
A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A., Haenig, C., Neuendorf, N., Blanc, E., Ivanov, A., Kirchner, M., Schleumann, P., Bayraktaroğlu, I., Richter, M., Molenda, C.M., Sporbert, A., Zenkner, M., Schnoegl, S., Suenkel, C., Schneider, L.S., Rybak-Wolf, A., Kochnowsky, B., Byrne, L.M., Wild, E.J., Nielsen, J.E., Dittmar, G., Peters, O., Beule, D. and Wanker, E.E.
Genome Medicine 15
(1): 50.
20 July 2023
Combining metabolic pulse labeling and quantitative proteomics to monitor protein synthesis upon viral infection.
Bogdanow, B., Katsimani, N., Liu, F. and Selbach, M.
Methods in Molecular Biology 2610
: 149-165.
2023
Brain-wide connectivity map of mouse thermosensory cortices.
Bokiniec, P., Whitmire, C.J., Leva, T.M. and Poulet, J.F.A.
Cerebral Cortex 33
(8): 4870-4885.
15 April 2023
Lipid nanoparticle-mediated hit-and-run approaches yield efficient and safe in situ gene editing in human skin.
Bolsoni, J., Liu, D., Mohabatpour, F., Ebner, R., Sadhnani, G., Tafech, B., Leung, J., Shanta, S., An, K., Morin, T., Chen, Y., Arguello, A., Choate, K., Jan, E., Ross, C.J.D., Brambilla, D., Witzigmann, D., Kulkarni, J., Cullis, P.R. and Hedtrich, S.
ACS Nano 17
(21): 22046-22059.
14 November 2023
Molecular characterization of the intact mouse muscle spindle using a multi-omics approach.
Bornstein, B., Heinemann-Yerushalmi, L., Krief, S., Adler, R., Dassa, B., Leshkowitz, D., Kim, M.C., Bewick, G., Banks, R.W. and Zelzer, E.
eLife 12
: e81843.
6 February 2023
A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies.
Brasanac, J. and Chien, C.
Frontiers in Human Neuroscience 17
: 1151531.
11 May 2023
Immune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple sclerosis.
Brune-Ingebretsen, S., Høgestøl, E.A., de Rosbo, N.K., Berg-Hansen, P., Brunborg, C., Blennow, K., Zetterberg, H., Paul, F., Uccelli, A., Villoslada, P., Harbo, H.F and Berge, T.
Journal of Neuroimmunology 382
: 578175.
15 September 2023
Health-related quality of life in patients with spinocerebellar ataxia: a validation study of the EQ-5D-3L.
Buchholz, M., Weber, N., Rädke, A., Faber, J., Schmitz-Hübsch, T., Jacobi, H., Xie, F., Klockgether, T. and Michalowsky, B.
Cerebellum 23
(3): 1020-1030.
June 2023
Synapsin autoantibodies during pregnancy are associated with fetal abnormalities.
Bünger, I., Talucci, I., Kreye, J., Höltje, M., Makridis, K.L., Foverskov Rasmussen, H., van Hoof, S., Cordero-Gomez, C., Ullrich, T., Sedlin, E., Kreissner, K.O., Hoffmann, C., Milovanovic, D., Turko, P., Paul, F., Meckies, J., Verlohren, S., Henrich, W., Chaoui, R., Maric, H.M., Kaindl, A.M. and Prüss, H.
Brain, Behavior & Immunity - Health 33
: 100678.
November 2023
Optical coherence tomography reflects clinically relevant gray matter damage in patients with multiple sclerosis.
Cagol, A., Fuertes, N.C., Stoessel, M., Barakovic, M., Schaedelin, S., D'Souza, M., Würfel, J., Brandt, A.U., Kappos, L., Sprenger, T., Naegelin, Y., Kuhle, J., Granziera, C. and Papadopoulou, A.
Journal of Neurology 270
(4): 2139-2148.
April 2023
Mortality of neuromyelitis optica spectrum disorder patients in an Argentinean population: a study from the RelevarEM registry.
Carnero Contentti, E., Lopez, P.A., Pettinicchi, J.P., Criniti, J., Pappolla, A., Miguez, J., Cristiano, E., Patrucco, L., Liwacki, S., Tkachuk, V., Balbuena, M.E., Vrech, C., Deri, N., Correale, J., Marrodan, M., Ysrraelit, M.C., Leguizamon, F., Luetic, G., Menichini, M.L., Tavolini, D., Mainella, C., Zanga, G., Burgos, M., Hryb, J., Barboza, A., Lazaro, L., Alonso, R., Fernández Liguori, N., Nadur, D., Alonso Serena, M., Caride, A., Paul, F. and Rojas, J.I.
Multiple Sclerosis Journal Experimental Translational and Clinical 9
(4): 20552173231205444.
17 October 2023
Frequency of new asymptomatic MRI lesions during attacks and follow-up of patients with NMOSD in a real-world setting.
Carnero Contentti, E., Lopez, P.A., Tkachuk, V., Vrech, C., Zarate, M.A., Correale, J., Deri, N., Luetic, G., Marrodan, M., Pagani Cassara, F., Tavolini, D., Ysrraelit, M.C., Balbuena, M.E., Hryb, J., Chiganer, E., Leguizamon, F., Knorre, E., Zanga, G., Pestchanker, C., Barboza, A., Nadur, D., Cristiano, E., Patrucco, L., Alonso, R., Alonso Serena, M., Paul, F. and Rojas, J.I.
Multiple Sclerosis Journal 29
(10): 1240-1249.
September 2023
MRI to differentiate multiple sclerosis, neuromyelitis optica, and myelin oligodendrocyte glycoprotein antibody disease.
Carnero Contentti, E., Okuda, D.T., Rojas, J.I., Chien, C., Paul, F. and Alonso, R.
Journal of Neuroimaging 33
(5): 688-702.
September 2023
Towards hierarchical regional transformer-based multiple instance learning.
Cersovsky, J., Mohammadi, S., Kainmueller, D. and Hoehne, J.
In: 2023 IEEE/CVF International Conference on Computer Vision Workshops (ICCVW), 02-06 Oct 2023, Paris, France.
25 December 2023
First demonstration of miRNA-dependent mRNA decay.
Chekulaeva, M.
Nature Reviews Molecular Cell Biology 24
(3): 164.
March 2023
Do early relapses predict the risk of long-term relapsing disease in an adult and paediatric cohort with MOGAD?
Chen, B., Gomez-Figueroa, E., Redenbaugh, V., Francis, A., Satukijchai, C., Wu, Y., Messina, S., Sa, M., Woodhall, M., Paul, F., Robertson, N.P., Lim, M., Wassmer, E., Kneen, R., Huda, S., Blain, C., Halfpenny, C., Hemingway, C., O'Sullivan, E., Hobart, J., Fisniku, L.K., Martin, R.J., Dobson, R., Cooper, S.A., Williams, V., Waters, P., Chen, J.J., Pittock, S.J., Ramdas, S., Leite, M.I., Flanagan, E.P., Geraldes, R. and Palace, J.
Annals of Neurology 94
(3): 508-517.
September 2023
Mepolizumab as an effective treatment in a case of hypophysitis in eosinophilic granulomatosis with polyangiitis.
Chen, J., Alexander, T., Walter-Rittel, T., Ziagaki, A. and Siffrin, V.
Therapeutic Advances in Neurological Disorders 16
: 17562864231182519.
2023
TREM2 promotes glioma progression and angiogenesis mediated by microglia/brain macrophages.
Chen, X., Zhao, Y., Huang, Y., Zhu, K., Zeng, F., Zhao, J., Zhang, H., Zhu, X., Kettenmann, H. and Xiang, X.
Glia 71
(11): 2679-2695.
November 2023
Translation and validation of the multiple sclerosis walking scale 12 for the German population - the MSWS-12/D.
Chorschew, A., Kesgin, F., Bellmann-Strobl, J., Flachenecker, P., Schiffmann, I., Rosenthal, F., Althoff, P., Drebinger, D., Arsenova, R., Rasche, L., Dorsch, E.M., Heesen, C., Paul, F., Stellmann, J.P. and Schmitz-Hübsch, T.
Health and Quality of Life Outcomes 21
(1): 110.
9 October 2023
Clinical and MRI measures to identify non-acute MOG-antibody disease in adults.
Cortese, R., Battaglini, M., Prados, F., Bianchi, A., Haider, L., Jacob, A., Palace, J., Messina, S., Paul, F., Wuerfel, J., Marignier, R., Durand-Dubief, F., de Medeiros Rimkus, C., Callegaro, D., Sato, D.K., Filippi, M., Rocca, M.A., Cacciaguerra, L., Rovira, A., Sastre-Garriga, J., Arrambide, G., Liu, Y., Duan, Y., Gasperini, C., Tortorella, C., Ruggieri, S., Amato, M.P., Ulivelli, M., Groppa, S., Grothe, M., Llufriu, S., Sepulveda, M., Lukas, C., Bellenberg, B., Schneider, R., Sowa, P., Celius, E.G., Proebstel, A.K., Yaldizli, Ö., Müller, J., Stankoff, B., Bodini, B., Carmisciano, L., Sormani, M.P., Barkhof, F., De Stefano, N. and Ciccarelli, O.
Brain 146
(6): 2489-2501.
June 2023
Mesoangioblasts at 20: from the embryonic aorta to the patient bed.
Cossu, G., Tonlorenzi, R., Brunelli, S., Sampaolesi, M., Messina, G., Azzoni, E., Benedetti, S., Biressi, S., Bonfanti, C., Bragg, L., Camps, J., Cappellari, O., Cassano, M., Ciceri, F., Coletta, M., Covarello, D., Crippa, S., Cusella-De Angelis, M.G., De Angelis, L., Dellavalle, A., Diaz-Manera, J., Galli, D., Galli, F., Gargioli, C., Gerli, M.F.M., Giacomazzi, G., Galvez, B.G., Hoshiya, H., Guttinger, M., Innocenzi, A., Minasi, M.G., Perani, L., Previtali, S.C., Quattrocelli, M., Ragazzi, M., Roostalu, U., Rossi, G., Scardigli, R., Sirabella, D., Tedesco, F.S., Torrente, Y. and Ugarte, G.
Frontiers in Genetics 13
: 1056114.
4 January 2023
N2 year in review.
Dalmau, J., Dalakas, M.C., Kolson, D.L., Paul, F., Sánchez-Valle, R. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 10
(1): e200076.
January 2023
HMGXB4 targets Sleeping Beauty transposition to germinal stem cells.
Devaraj, A., Singh, M., Narayanavari, S.A., Yong, G., Chen, J., Wang, J., Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z., Raskó, T., Radscheit, K., Selbach, M., Ivics, Z. and Izsvak, Z.
International Journal of Molecular Sciences 24
(8): 7283.
14 April 2023
Progression events defined by home-based assessment of motor function in multiple sclerosis: protocol of a prospective study.
Dorsch, E.M., Röhling, H.M., Zocholl, D., Hafermann, L., Paul, F. and Schmitz-Hübsch, T.
Frontiers in Neurology 14
: 1258635.
10 October 2023
"Biofeedback-based return to sport": individualization through objective assessments.
Ekizos, A. and Santuz, A.
Frontiers in Physiology 14
: 1185556.
12 June 2023
Telemedicine in neuromuscular diseases during Covid-19 pandemic: ERN-NMD European survey.
El-Hassar, L., Amara, A., Sanson, B., Lacatus, O., Amir Belhouchet, A., Kroneman, M., Claeys, K., Plançon, J.P., Rodolico, C., Primiano, G., Trojsi, F., Filosto, M., Mongini, T.E., Bortolani, S., Monforte, M., Carraro, E., Maggi, L., Ricci, F., Silani, V., Orsucci, D., Créange, A., Péréon, Y., Stojkovic, T., van der Beek, N.A.M.E., Toscano, A., Pareyson, D., Attarian, S., Van den Bergh, P.Y.K., Remiche, G., Hoeijmakers, J.G.J., Badrising, U., Voermans, N.C., Kaindl, A.M., Schara-Schmidt, U., Schoser, B., Gazzerro, E., Haberlová, Ja., Voháňka, S., Pál, E., Molnar, M. J., Leonardis, L., Tournev, I.L., Osorio, A.N., Olivé, M., Muelas, N., Alonso-Perez, J., de Visser, M., Siciliano, G. and Sacconi, S.
Journal of Neuromuscular Diseases 10
(2): 173-184.
7 March 2023
Machine learning-based prediction of clinical outcomes after first-ever ischemic stroke.
Fast, L., Temuulen, U., Villringer, K., Kufner, A., Ali, H.F., Siebert, E., Huo, S., Piper, S.K., Sperber, P.S., Liman, T., Endres, M. and Ritter, K.
Frontiers in Neurology 14
: 1114360.
21 February 2023
Occurrence and risk factors of relapse activity after vaccination against COVID-19 in people with multiple sclerosis: 1-year follow-up results from a nationwide longitudinal observational study.
Fneish, F., Frahm, N., Peters, M., Ellenberger, D., Haas, J., Löbermann, M., Pöhlau, D., Röper, A.L., Schilling, S., Stahmann, A., Temmes, H., Paul, F. and Zettl, U.K.
Vaccines 11
(12): 1859.
16 December 2023
Frequency and predictors of relapses following SARS-CoV-2 vaccination in patients with multiple sclerosis: interim results from a longitudinal observational study.
Frahm, N., Fneish, F., Ellenberger, D., Haas, J., Löbermann, M., Peters, M., Pöhlau, D., Röper, A.L., Schilling, S., Stahmann, A., Temmes, H., Paul, F. and Zettl, U.K.
Journal of Clinical Medicine 12
(11): 3640.
24 May 2023
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
Franz, A., Weber, A.I., Preußner, M., Dimos, N., Stumpf, A., Ji, Y., Moreno-Velasquez, L., Voigt, A., Schulz, F., Neumann, A., Kuropka, B., Kuehn, R., Urlaub, H., Schmitz, D., Wahl, M.C. and Heyd, F.
Life Science Alliance 6
(3): e202201826.
March 2023
c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy.
Frezel, N., Ranucci, M., Foster, E., Wende, H., Pelczar, P., Mendes, R., Ganley, R.P., Werynska, K., d'Aquin, S., Beccarini, C., Birchmeier, C., Zeilhofer, H.U. and Wildner, H.
Cell Reports 42
(4): 112295.
21 March 2023
Treadmill training with virtual reality to enhance gait and cognitive function among people with multiple sclerosis: a randomized controlled trial.
Galperin, I., Mirelman, A., Schmitz-Hübsch, T., Hsieh, K.L., Regev, K., Karni, A., Brozgol, M., Cornejo Thumm, P., Lynch, S.G., Paul, F., Devos, H., Sosnoff, J. and Hausdorff, J.M.
Journal of Neurology 270
(3): 1388-1401.
March 2023
Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function.
Geng, S., Paul, F., Kowalczyk, I., Raimundo, S., Sporbert, A., Mamo, T.M. and Hammes, A.
Frontiers in Cell and Developmental Biology 11
: 1173688.
7 April 2023
"suMus," a novel digital system for arm movement metrics and muscle energy expenditure.
Gerhalter, Teresa, Müller, Christina, Maron, Elke, Thielen, Markus, Schätzl, Teresa, Mähler, A., Schütte, T., Boschmann, M., Herzer, René, Spuler, S. and Gazzerro, E.
Frontiers in Physiology 14
: 1057592.
26 January 2023
1,2-(13)C(2)-glucose tracing approach to assess metabolic alterations of human monocytes under neuroinflammatory conditions.
Giacomello, G., Otto, C., Priller, J., Ruprecht, K., Böttcher, C. and Parr, M.K.
Current Issues in Molecular Biology 45
(1): 765-781.
16 January 2023
Play and tickling responses map to the lateral columns of the rat periaqueductal gray.
Gloveli, N., Simonnet, J., Tang, W., Concha-Miranda, M., Maier, E., Dvorzhak, A., Schmitz, D. and Brecht, M.
Neuron 111
(19): 3041-3052.
4 October 2023
Internet-delivered cognitive behavioural therapy programme to reduce depressive symptoms in patients with multiple sclerosis: a multicentre, randomised, controlled, phase 3 trial.
Gold, S.M., Friede, T., Meyer, B., Moss-Morris, R., Hudson, J., Asseyer, S., Bellmann-Strobl, J., Leisdon, A., Ißels, L., Ritter, K., Schymainski, D., Pomeroy, H., Lynch, S.G., Cozart, J.S., Thelen, J., Román, C.A.F., Cadden, M., Guty, E., Lau, S., Pöttgen, J., Ramien, C., Seddiq-Zai, S., Kloidt, A.M., Wieditz, J., Penner, I.K., Paul, F., Sicotte, N.L., Bruce, J.M., Arnett, P.A. and Heesen, C.
Lancet Digital Health 5
(10): e668-e678.
October 2023
Sex-specific microglia state in the neuroligin-4 knock-out mouse model of autism spectrum disorder.
Guneykaya, D., Ugursu, B., Logiacco, F., Popp, O., Feiks, M.A., Meyer, N., Wendt, S., Semtner, M., Cherif, F., Gauthier, C., Madore, C., Yin, Z., Çınar, Ö., Arslan, T., Gerevich, Z., Mertins, P., Butovsky, O., Kettenmann, H. and Wolf, S.A.
Brain Behavior and Immunity 111
: 61-75.
July 2023
No secondary treatment failure during incobotulinumtoxin-A long-term treatment demonstrated by the drawing of disease severity.
Hefter, H., Brauns, R., Ürer, B., Rosenthal, D., Albrecht, P. and Samadzadeh, S.
Toxins 15
(7): 454.
12 July 2023
Differences in the time course of recovery from brain and liver dysfunction in conventional long-term treatment of Wilson disease.
Hefter, H., Kruschel, T.S., Novak, M., Rosenthal, D., Luedde, T., Meuth, S.G., Albrecht, P., Hartmann, C.J. and Samadzadeh, S.
Journal of Clinical Medicine 12
(14): 4861.
24 July 2023
Significantly lower antigenicity of incobotulinumtoxin than abo- or onabotulinumtoxin.
Hefter, H., Rosenthal, D., Jansen, A., Brauns, R., Ürer, B., Bigalke, H., Hartung, H.P., Meuth, S.G., Lee, J.I., Albrecht, P. and Samadzadeh, S.
Journal of Neurology 270
(2): 788-796.
February 2023
"Pseudo"-secondary treatment failure explained via disease progression and effective botulinum toxin therapy: a pilot simulation study.
Hefter, H., Rosenthal, D. and Samadzadeh, S.
Toxins 15
(10): 618.
18 October 2023
Exploring the interplay between the clinical and presumed effect of botulinum injections for cervical dystonia: a pilot study.
Hefter, H. and Samadzadeh, S.
Toxins 15
(10): 592.
30 September 2023
Lessons about botulinum toxin A therapy from cervical dystonia patients drawing the course of disease: a pilot study.
Hefter, H., Schomaecker, I., Schomaecker, M., Ürer, B., Brauns, R., Rosenthal, D., Albrecht, P. and Samadzadeh, S.
Toxins 15
(7): 431.
30 June 2023
Autoimmunenzephalitis - ein Update [Autoimmune encephalitis - an update].
Heine, J., Duchow, A., Rust, R., Paul, F., Prüß, H. and Finke, C.
Nervenarzt 94
(6): 525-537.
June 2023
Structural brain changes in patients with post-COVID fatigue: a prospective observational study.
Heine, J., Schwichtenberg, K., Hartung, T.J., Rekers, S., Chien, C., Boesl, F., Rust, R., Hohenfeld, C., Bungenberg, J., Costa, A.S., Scheibenbogen, C., Bellmann-Strobl, J., Paul, F., Franke, C., Reetz, K. and Finke, C.
EClinicalMedicine 58
: 101874.
April 2023
Accelerated simultaneous T2 and T2* mapping of multiple sclerosis lesions using compressed sensing reconstruction of radial RARE-EPI MRI.
Herrmann, C.J.J., Starke, L., Millward, J.M., Kuchling, J., Paul, F. and Niendorf, T.
Tomography 9
(1): 299-314.
31 January 2023
Effects of the COVID-19 pandemic on patients with NMO spectrum disorders and MOG-antibody-associated diseases: COPANMO(G)-Study.
Hümmert, M.W., Bütow, F., Tkachenko, D., Ayzenberg, I., Pakeerathan, T., Hellwig, K., Klotz, L., Häußler, V., Stellmann, J.P., Warnke, C., Goereci, Y., Etgen, T., Luessi, F., Bronzlik, P., Gingele, S., Lauenstein, A.S., Kleiter, I., Rommer, P.S., Paul, F., Bellmann-Strobl, J., Duchow, A., Then Bergh, F., Pul, R., Walter, A., Pellkofer, H., Kümpfel, T., Pompsch, M., Kraemer, M., Albrecht, P., Aktas, O., Ringelstein, M., Senel, M., Giglhuber, K., Berthele, A., Jarius, S., Wildemann, B. and Trebst, C.
Neurology Neuroimmunology & Neuroinflammation 10
(2): e200082.
March 2023
Cognition in patients with neuromyelitis optica spectrum disorders: a prospective multicentre study of 217 patients (CogniNMO-Study).
Hümmert, M.W., Stern, C., Paul, F., Duchow, A., Bellmann-Strobl, J., Ayzenberg, I., Schwake, C., Kleiter, I., Hellwig, K., Jarius, S., Wildemann, B., Senel, M., Berthele, A., Giglhuber, K., Luessi, F., Grothe, M., Klotz, L., Schülke, R., Gingele, S., Faiss, J.H., Walter, A., Warnke, C., Then Bergh, F., Aktas, O., Ringelstein, M., Stellmann, J.P., Häußler, V., Havla, J., Pellkofer, H., Kümpfel, T., Kopp, B. and Trebst, C.
Multiple Sclerosis Journal 29
(7): 819-831.
June 2023
Monitoring mitochondrial translation by pulse SILAC.
Imami, K., Selbach, M. and Ishihama, Y.
Journal of Biological Chemistry 299
(2): 102865.
February 2023
Stat1 is an inducible transcriptional repressor of neural stem cells self-renewal program during neuroinflammation.
Imitola, J., Hollingsworth, E.W., Watanabe, F., Olah, M., Elyaman, W., Starossom, S.C., Kivisäkk, P. and Khoury, S.J.
Frontiers in Cellular Neuroscience 17
: 1156802.
16 August 2023
Real-world evidence of ocrelizumab-treated relapsing multiple sclerosis cohort shows changes in progression independent of relapse activity mirroring phase 3 trials.
Ingwersen, J., Masanneck, L., Pawlitzki, M., Samadzadeh, S., Weise, M., Aktas, O., Meuth, S.G. and Albrecht, P.
Scientific Reports 13
(1): 15003.
11 September 2023
Disease progression of spinocerebellar ataxia types 1, 2, 3 and 6 before and after ataxia onset.
Jacobi, H., Schaprian, T., Schmitz-Hübsch, T., Schmid, M. and Klockgether, T.
Annals of Clinical and Translational Neurology 10
(10): 1833-1843.
October 2023
Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis.
Jarius, S., Aktas, O., Ayzenberg, I., Bellmann-Strobl, J., Berthele, A., Giglhuber, K., Häußler, V., Havla, J., Hellwig, K., Hümmert, M.W., Kleiter, I., Klotz, L., Krumbholz, M., Kümpfel, T., Paul, F., Ringelstein, M., Ruprecht, K., Senel, M., Stellmann, J.P., Bergh, F.T., Tumani, H., Wildemann, B. and Trebst, C.
Journal of Neurology 270
(7): 3341-3368.
July 2023
Small molecule specifically inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation.
Jordan, P., Costa, A., Specker, E., Popp, O., Volkamer, A., Piske, R., Obrusnik, T., Kleissle, S., Stuke, K., Rex, A., Neuenschwander, M., von Kries, J.P., Nazare, M., Mertins, P., Kettenmann, H. and Wolf, S.A.
PLoS ONE 18
(2): e0278325.
6 February 2023
Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy.
Kalkan, H., Pagano, E., Paris, D., Panza, E., Cuozzo, M., Moriello, C., Piscitelli, F., Abolghasemi, A., Gazzerro, E., Silvestri, C., Capasso, R., Motta, A., Russo, R., Di Marzo, V. and Iannotti, F.A.
EMBO Molecular Medicine 15
(3): e16225.
8 March 2023
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
Kapell, H., Fazio, L., Dyckow, J., Schwarz, S., Cruz-Herranz, A., Campos, J., Mayer, C., D Este, E., Möbius, W., Cordano, C., Pröbstel, A.K., Gharagozloo, M., Zulji, A., Narayanan Naik, V., Delank, A.K., Cerina, M., Müntefering, T., Lerma-Martin, C., Sonner, J.K., Sin, J.H., Disse, P., Rychlik, N., Sabeur, K., Chavali, M., Srivastava, R., Heidenreich, M., Fitzgerald, K.C., Seebohm, G., Stadelmann, C., Hemmer, B., Platten, M., Jentsch, T.J., Engelhardt, M., Budde, T., Nave, K.A., Calabresi, P.A., Friese, M.A., Green, A.J., Acuna, C., Rowitch, D.H., Meuth, S.G. and Schirmer, L.
Journal of Clinical Investigation 133
(7): e164223.
3 April 2023
iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J., Muinjonov, B., Rosiewicz, K.S., Diecke, S., Biese, C., Schiweck, J., Chien, C., Zocholl, D., Conrad, T., Paul, F., Alisch, M. and Siffrin, V.
Journal of Clinical Investigation 133
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3 July 2023
Discrimination of multiple sclerosis using OCT images from two different centers.
Khodabandeh, Z., Rabbani, H., Ashtari, F., Zimmermann, H.G., Motamedi, S., Brandt, A.U., Paul, F. and Kafieh, R.
Multiple Sclerosis and Related Disorders 77
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September 2023
Inebilizumab reduces neuromyelitis optica spectrum disorder risk independent of FCGR3A polymorphism.
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Annals of Clinical and Translational Neurology 10
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December 2023
Mutations in plasticity-related-gene-1 (PRG-1) protein contribute to hippocampal seizure susceptibility and modify epileptic phenotype.
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15 June 2023
Eleven strategies for making reproducible research and open science training the norm at research institutions.
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eLife 12
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23 November 2023
Immunomodulatory effects of new phenanthrene derivatives from Dendrobium crumenatum.
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26 May 2023
Preclinical safety and efficacy of a therapeutic antibody that targets SARS-CoV-2 at the sotrovimab face but is escaped by Omicron.
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iScience 26
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21 April 2023
Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia.
Kuhrt, L.D., Motta, E., Elmadany, N., Weidling, H., Fritsche-Guenther, R., Efe, I.E., Cobb, O., Chatterjee, J., Boggs, L.G., Schnauß, M., Diecke, S., Semtner, M., Anastasaki, C., Gutmann, D.H. and Kettenmann, H.
Disease Models & Mechanisms 16
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December 2023
Visualizing MyoD oscillations in muscle stem cells.
Lahmann, I. and Birchmeier, C.
Methods in Molecular Biology 2640
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2023
Discriminating promiscuous from target-specific autoantibodies in COVID-19.
Lebedin, M., Vazquez Garcia, C., Spatt, L., Ratswohl, C., Thibeault, C., Ostendorf, L., Alexander, T., Paul, F., Sander, L.E., Kurth, F. and de la Rosa, K.
European Journal of Immunology 53
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May 2023
Long-term symptom severity and clinical biomarkers in post-COVID-19/chronic fatigue syndrome: results from a prospective observational cohort.
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EClinicalMedicine 63
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19 August 2023
Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini, I., Emmenegger, L., Zappulo, A., Rybak-Wolf, A., Wurmus, R., Oliveras Martinez, A., Cerda Jara, C., Boltengagen, A., Hessler, T., Mastrobuoni, G., Kempa, S., Zinzen, R., Woehler, A. and Rajewsky, N.
Nature Methods 20
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October 2023
Thermosensory thalamus: parallel processing across model organisms.
Leva, T. and Whitmire, C.
Frontiers in Neuroscience 17
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13 October 2023
Brain blood vessel autoantibodies in patients with NMDA and GABAA receptor encephalitis: identification of unconventional Myosin-X as target antigen.
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Frontiers in Cellular Neuroscience 17
30 January 2023
Combining in vivo proton exchange rate (k(ex)) MRI with quantitative susceptibility mapping to further stratify the gadolinium-negative multiple sclerosis lesions.
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Frontiers in Neuroscience 16
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11 January 2023
Robust phenotyping of highly multiplexed tissue imaging data using pixel-level clustering.
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Nature Communications 14
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1 August 2023
Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels.
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Cell Reports 42
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29 August 2023
Bruton's tyrosine kinase-bearing B cells and microglia in neuromyelitis optica spectrum disorder.
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Journal of Neuroinflammation 20
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21 December 2023
mRNA stability and m(6)A are major determinants of subcellular mRNA localization in neurons.
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Molecular Cell 83
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3 August 2023
Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic.
Logiacco, F., Grzegorzek, L.C., Cordell, E.C., Popp, O., Mertins, P., Gutmann, D.H., Kettenmann, H. and Semtner, M.
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9 March 2023
Intravenous immunoglobulin treatment for acute attacks in myelin oligodendrocyte glycoprotein antibody disease.
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Multiple Sclerosis Journal 29
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August 2023
Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
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Neuron 111
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19 July 2023
Investigating the mitoprotective effects of S1P receptor modulators ex vivo using a novel semi-automated live imaging set-up.
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International Journal of Molecular Sciences 25
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23 December 2023
Association of obesity with disease outcome in multiple sclerosis.
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January 2023
SaFiDe: detection of saccade and fixation periods based on eye-movement attributes from video-oculography, scleral coil or electrooculography data.
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24 January 2023
Automated reconstruction of whole-embryo cell lineages by learning from sparse annotations.
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Nature Biotechnology 44
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January 2023
Functional connectome fingerprinting and stability in multiple sclerosis.
Mantwill, M., Asseyer, S., Chien, C., Kuchling, J., Schmitz-Hübsch, T., Brandt, A.U., Haynes, J.D., Paul, F. and Finke, C.
Multiple Sclerosis Journal Experimental Translational and Clinical 9
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25 August 2023
The IgCAM CAR regulates gap junction-mediated coupling on embryonic cardiomyocytes and affects their beating frequency.
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Life 13
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Early spinal cord pseudoatrophy in interferon-beta treated multiple sclerosis.
Matusche, B., Litvin, L., Schneider, R., Bellenberg, B., Mühlau, M., Pongratz, V., Berthele, A., Groppa, S., Muthuraman, M., Zipp, F., Paul, F., Wiendl, H., Meuth, S.G., Sämann, P., Weber, F., Linker, R.A., Kümpfel, T., Gold, R. and Lukas, C.
European Journal of Neurology 30
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February 2023
The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
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Nature Communications 14
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3 March 2023
A searchable image resource of Drosophila GAL4-driver expression patterns with single neuron resolution.
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eLife 12
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Massively parallel identification of mRNA localization elements in primary cortical neurons.
Mendonsa, S., von Kügelgen, N., Dantsuji, S., Ron, M., Breimann, L., Baranovskii, A., Lödige, I., Kirchner, M., Fischer, M., Zerna, N., Bujanic, L., Mertins, P., Ulitsky, I. and Chekulaeva, M.
Nature Neuroscience 26
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March 2023
Inflammatory cytokines associated with multiple sclerosis directly induce alterations of neuronal cytoarchitecture in human neurons.
Meyer-Arndt, L., Kerkering, J., Kuehl, T., Gil Infante, A., Paul, F., Rosiewicz, K.S., Siffrin, V. and Alisch, M.
Journal of Neuroimmune Pharmacology 18
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June 2023
Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence.
Miller, D.C., Lisowski, P., Genehr, C., Wanker, E.E., Priller, J., Prigione, A. and Diecke, S.
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April 2023
Optical coherence tomography angiography measurements in multiple sclerosis: a systematic review and meta-analysis.
Mohammadi, S., Gouravani, M., Salehi, M.A., Arevalo, J.F., Galetta, S.L., Harandi, H., Frohman, E.M., Frohman, T.C., Saidha, S., Sattarnezhad, N. and Paul, F.
Journal of Neuroinflammation 20
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27 March 2023
Lack of the Ig cell adhesion molecule BT-IgSF (IgSF11) induced behavioral changes in the open maze, water maze and resident intruder test.
Montag, D., Pelz, L. and Rathjen, F.G.
PLoS ONE 18
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6 January 2023
Complicated monkeypox infection in a patient with multiple sclerosis and fingolimod treatment.
Müller-Jensen, L., Kriedemann, H., Anvari, K., Huehnchen, P. and Siffrin, V.
Neurology 100
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4 April 2023
Cas9-induced single cut enables highly efficient and template-free repair of a muscular dystrophy causing founder mutation.
Müthel, S., Marg, A., Ignak, B., Kieshauer, J., Escobar, H., Stadelmann, C. and Spuler, S.
Molecular Therapy - Nucleic Acids 13
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March 2023
Role of TMEM100 in mechanically insensitive nociceptor un-silencing.
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Nature Communications 14
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5 April 2023
A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A., Bakina, O., Badillo Lisakowski, V., Olivares-Chauvet, P., Conrad, T., Gotthardt, M., Kettenmann, H. and Junker, J.P.
Molecular Systems Biology 19
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10 February 2023
Delimiting MOGAD as a disease entity using translational imaging.
Oertel, F.C., Hastermann, M. and Paul, F.
Frontiers in Neurology 14
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7 December 2023
Visually evoked potential as prognostic biomarker for neuroaxonal damage in multiple sclerosis from a multicenter longitudinal cohort.
Oertel, F.C., Krämer, J., Motamedi, S., Keihani, A., Zimmermann, H.G., Dimitriou, N.G., Condor-Montes, S., Bereuter, C., Cordano, C., Abdelhak, A., Trip, A., Aktas, O., Meuth, S.G., Wiendl, H., Ruprecht, K., Bellmann-Strobl, J., Paul, F., Petzold, A., Brandt, A.U., Albrecht, P. and Green, A.J.
Neurology Neuroimmunology & Neuroinflammation 10
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May 2023
Retinal changes after acute and late optic neuritis in aquaporin-4 antibody seropositive NMOSD.
Oertel, F.C., Zimmermann, H.G., Motamedi, S., Bereuter, C., Asseyer, E.S., Chien, C., Marignier, R., Cobo-Calvo, A., Leocani, L., Pisa, M., Radaelli, M., Villoslada, P., Sanchez-Dalmau, B., Martinez-Lapiscina, E.H., Lana-Peixoto, M.A., Fontenelle, M.A., Aktas, O., Ringelstein, M., Albrecht, P., Green, A.J., Yeaman, M.R., Smith, T.J., Cook, L., Paul, F. and Brandt, A.U.
Journal of Neuro-Ophthalmology
29 September 2023
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Diagnostic value of intereye difference metrics for optic neuritis in aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders.
Oertel, F.C., Zimmermann, H.G., Motamedi, S., Chien, C., Aktas, O., Albrecht, P., Ringelstein, M., Dcunha, A., Pandit, L., Martinez-Lapiscina, E.H., Sanchez-Dalmau, B., Villoslada, P., Palace, J., Roca-Fernández, A., Leite, M.I., Sharma, S.M., Leocani, L., Pisa, M., Radaelli, M., Lana-Peixoto, M.A., Fontenelle, M.A., Havla, J., Ashtari, F., Kafieh, R., Dehghani, A., Pourazizi, M., Marignier, R., Cobo-Calvo, A., Asgari, N., Jacob, A., Huda, S., Mao-Draayer, Y., Green, A.J., Kenney, R., Yeaman, M.R., Smith, T.J., Cook, L., Brandt, A.U., Paul, F. and Petzold, A.
Journal of Neurology, Neurosurgery, and Psychiatry 94
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Pathophysiology and differentiation from other symptoms and diseasess.
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International delphi consensus on the management of AQP4-IgG+ NMOSD: recommendations for eculizumab, inebilizumab, and satralizumab.
Paul, F., Marignier, R., Palace, J., Arrambide, G., Asgari, N., Bennett, J.L., Cree, B.A.C., De Sèze, J., Fujihara, K., Kim, H.J., Hornby, R., Huda, S., Kissani, N., Kleiter, I., Kuwabara, S., Lana-Peixoto, M., Law, L., Leite, M.I., Pandit, L., Pittock, S.J., Quan, C., Ramanathan, S., Rotstein, D., Saiz, A., Sato, D.K. and Vaknin-Dembinsky, A.
Neurology Neuroimmunology & Neuroinflammation 10
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July 2023
SLC26A1 is a major determinant of sulfate homeostasis in humans.
Pfau, A., López-Cayuqueo, K.I., Scherer, N., Wuttke, M., Wernstedt, A., González Fassrainer, D., Smith, D.E., van de Kamp, J.M., Ziegeler, K., Eckardt, K.U., Luft, F.C., Aronson, P.S., Köttgen, A., Jentsch, T.J. and Knauf, F.
Journal of Clinical Investigation 133
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1 February 2023
Estimation of migraine prevalence considering active and inactive states across different age groups.
Piccininni, M., Brinks, R., Rohmann, J.L. and Kurth, T.
Journal of Headache and Pain 24
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11 July 2023
Ravulizumab in aquaporin-4-positive neuromyelitis optica spectrum disorder.
Pittock, S.J., Barnett, M., Bennett, J.L., Berthele, A., de Seze, J., Levy, M., Nakashima, I., Oreja-Guevara, C., Palace, J., Paul, F., Pozzilli, C., Yountz, M., Allen, K., Mashhoon, Y. and Kim, H.J.
Annals of Neurology 93
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June 2023
Multiple sclerosis and circadian rhythms: Can diet act as a treatment?
Pivovarova-Ramich, O., Zimmermann, H.G. and Paul, F.
Acta Physiologica 237
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April 2023
Cellular and synaptic diversity of layer 2-3 pyramidal neurons in human individuals.
Planert, H., Mittermaier, F.X., Grosser, S., Fidzinski, P., Schneider, U.C., Radbruch, H., Onken, J., Holtkamp, M., Schmitz, D., Alle, H., Vida, I., Geiger, J.R.P. and Peng, Y.
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Cryo-EM captures early ribosome assembly in action.
Qin, B., Lauer, S.M., Balke, A., Vieira-Vieira, C.H., Bürger, J., Mielke, T., Selbach, M., Scheerer, P., Spahn, C.M.T. and Nikolay, R.
Nature Communications 14
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17 February 2023
Visualization and data exploration of chromosome conformation capture data using Voronoi diagrams with v3c-viz.
Race, A.M., Fuchs, A. and Chung, H.R.
Scientific Reports 13
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12 December 2023
Microglia actively remove NR1 autoantibody-bound NMDA receptors and associated post-synaptic proteins in neuron microglia co-cultures.
Rahman, K.A., Orlando, M., Boulos, A., Andrzejak, E., Schmitz, D., Ziv, N.E., Prüss, H., Garner, C.C. and Ichkova, A.
Glia 71
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Comparable in vivo joint kinematics between self-reported stable and unstable knees after TKA can be explained by muscular adaptation strategies: a retrospective observational study.
Rao, L., Horn, N., Meister, N., Preiss, S., Taylor, W.R., Santuz, A. and Schütz, P.
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The IgSF cell adhesion protein CLMP and congenital short bowel syndrome (CSBS).
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International Journal of Molecular Sciences 24
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16 March 2023
Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells.
Reincke, S.M., von Wardenburg, N., Homeyer, M.A., Kornau, H.C., Spagni, G., Li, L.Y., Kreye, J., Sánchez-Sendín, E., Blumenau, S., Stappert, D., Radbruch, H., Hauser, A.E., Künkele, A., Edes, I., Schmitz, D. and Prüss, H.
Cell 186
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Translating principles of quality control to cardiovascular magnetic resonance: assessing quantitative parameters of the left ventricle in a large cohort.
Riazy, L., Däuber, S., Lange, S., Viezzer, D.S., Ott, S., Wiesemann, S., Blaszczyk, E., Mühlberg, F., Zange, L. and Schulz-Menger, J.
Scientific Reports 13
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Time-to-care metrics in patients with interhospital transfer for mechanical thrombectomy in north-east Germany: primary telestroke centers in rural areas vs. primary stroke centers in a metropolitan area.
Riegler, C., Behrens, J.R., Gorski, C., Angermaier, A., Kinze, S., Ganeshan, R., Rocco, A., Kunz, A., Müller, T.J., Bitsch, A., Grüger, A., Weber, J.E., Siebert, E., Bollweg, K., von Rennenberg, R., Audebert, H.J., Nolte, C.H. and Erdur, H.
Frontiers in Neurology 13
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9 January 2023
Visual function resists early neurodegeneration in the visual system in primary progressive multiple sclerosis.
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HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
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ACTIS: improving data efficiency by leveraging semi-supervised augmentation consistency training for instance segmentation.
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25 December 2023
Inhibitory effect of isopanduratin A on adipogenesis: a study of possible mechanisms.
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27 February 2023
Factors associated with depressive mood at the onset of multiple sclerosis - an analysis of 781 patients of the German NationMS cohort.
Salmen, A., Hoepner, R., Fleischer, V., Heldt, M., Gisevius, B., Motte, J., Ruprecht, K., Schneider, R., Fisse, A.L., Grüter, T., Lukas, C., Berthele, A., Giglhuber, K., Flaskamp, M., Mühlau, M., Kirschke, J., Bittner, S., Groppa, S., Lüssi, F., Bayas, A., Meuth, S., Heesen, C., Trebst, C., Wildemann, B., Then Bergh, F., Antony, G., Kümpfel, T., Paul, F., Nischwitz, S., Tumani, H., Zettl, U., Hemmer, B., Wiendl, H., Zipp, F. and Gold, R.
Therapeutic Advances in Neurological Disorders 16
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8 September 2023
Microfibrillar-associated protein 4 as a potential marker of acute relapse in inflammatory demyelinating diseases of the central nervous system: pathological and clinical aspects.
Samadzadeh, S., Olesen, M.N., Wirenfeldt, M., Möller, S., Misu, T., Soelberg, K., Frederiksen, J.L., Heegaard, S., Mariotto, S., Fujihara, K., Ruprecht, K., Andersen, T.L., Marignier, R., Lillevang, S.T., Flanagan, E.P., Pittock, S.J., Kim, H.J., Bennett, J.L., Paul, F., Sorensen, G.L., Weinshenker, B.G., Lassmann, H. and Asgari, N.
Multiple Sclerosis Journal 29
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14 December 2023
Proglucagon signalling in the rat dorsomedial hypothalamus - physiology and high-fat diet-mediated alterations.
Sanetra, A M., Palus-Chramiec, K., Chrobok, L., Jeczmien-Lazur, J.S., Klich, J.D. and Lewandowski, M.H.
Molecular and Cellular Neuroscience 126
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September 2023
Fighting post-COVID and ME/CFS - development of curative therapies.
Scheibenbogen, C., Bellmann-Strobl, J.T., Heindrich, C., Wittke, K., Stein, E., Franke, C., Prüss, H., Preßler, H., Machule, M.L., Audebert, H., Finke, C., Zimmermann, H.G., Sawitzki, B., Meisel, C., Toelle, M., Krueger, A., Aschenbrenner, A.C., Schultze, J.L., Beyer, M.D., Ralser, M., Mülleder, M., Sander, L.E., Konietschke, F., Paul, F., Stojanov, S., Bruckert, L., Hedderich, D.M., Knolle, F., Riemekasten, G., Vehreschild, M.J.G.T., Cornely, O.A., Behrends, U. and Burock, S.
Frontiers in Medicine 10
2023
Glial fibrillary acidic protein as a biomarker in neuromyelitis optica spectrum disorder: a current review.
Schindler, P., Aktas, O., Ringelstein, M., Wildemann, B., Jarius, S., Paul, F. and Ruprecht, K.
Expert Review of Clinical Immunology 19
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January 2023
Clinical rating scales for ataxia.
Schmitz-Hübsch, T.
Contemporary Clinical Neuroscience
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30 May 2023
Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J., Sundaravinayagam, D., Blume, A., Marg, A., Grunwald, S., Metzler, E., Escobar, H., Müthel, S., Wang, H., Wollersheim, T., Weber-Carstens, S., Akalin, A., Di Virgilio, M., Tursun, B. and Spuler, S.
International Journal of Molecular Sciences 24
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1 February 2023
Similar neural pathways link psychological stress and brain-age in health and multiple sclerosis.
Schulz, M.A., Hetzer, S., Eitel, F., Asseyer, S., Meyer-Arndt, L., Schmitz-Hübsch, T., Bellmann-Strobl, J., Cole, J.H., Gold, S.M., Paul, F., Ritter, K. and Weygandt, M.
iScience 26
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15 September 2023
Novel multi-objective affinity approach allows to identify pH-specific μ-opioid receptor agonists.
Secker, C., Fackeldey, K., Weber, M., Ray, S., Gorgulla, C. and Schütte, C.
Journal of Cheminformatics 15
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19 September 2023
The polyphenol EGCG directly targets intracellular amyloid-β aggregates and promotes their lysosomal degradation.
Secker, C., Motzny, A.Y., Kostova, S., Buntru, A., Helmecke, L., Reus, L., Steinfort, R., Brusendorf, L., Boddrich, A., Neuendorf, N., Diez, L., Schmieder, P., Schulz, A., Czekelius, C. and Wanker, E.E.
Journal of Neurochemistry 166
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18 July 2023
Multiple Sklerose.
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3 February 2023
GIPC1 regulates MACC1-driven metastasis.
Siegel, F., Schmidt, H., Juneja, M., Smith, J., Herrmann, P., Kobelt, D., Sharma, K., Fichtner, I., Walther, W., Dittmar, G., Volkmer, R., Rathjen, F.G., Schlag, P.M. and Stein, U.
Frontiers in Oncology 13
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8 December 2023
Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.
Silva, R.V., Biskup, K., Zabala-Jouvin, J.K., Batzdorf, C.S., Stellmach, C., Morr, A.S., Sack, I., Ludwig, A., Blanchard, V. and Infante-Duarte, C.
International Journal of Biological Macromolecules 230
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March 2023
Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.
Smith, E.J., Sathasivam, K., Landles, C., Osborne, G.F., Mason, M.A., Gomez-Paredes, C., Taxy, B.A., Milton, R.E., Ast, A., Schindler, F., Zhang, C., Duan, W., Wanker, E.E. and Bates, G.P.
Brain Communications 5
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20 January 2023
Depressive symptoms and anti-N-methyl-D-aspartate-receptor GluN1 antibody seropositivity in the PROSpective cohort with incident stroke.
Sperber, P.S., Gebert, P., Broersen, L.H.A., Kufner, A., Huo, S., Piper, S.K., Teegen, B., Heuschmann, P.U., Prüss, H., Endres, M., Liman, T.G. and Siegerink, B.
Brain Behavior & Immunity - Health 34
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December 2023
First in vivo fluorine-19 magnetic resonance imaging of the multiple sclerosis drug siponimod.
Starke, L., Millward, J.M., Prinz, C., Sherazi, F., Waiczies, H., Lippert, C., Nazaré, M., Paul, F., Niendorf, T. and Waiczies, S.
Theranostics 13
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5 February 2023
Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome - State of the art: Report of the 2nd international meeting at the Charité fatigue center.
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Autoimmunity Reviews 22
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November 2023
Digital motor biomarkers of cerebellar ataxia using an RGB-Depth camera-based motion analysis system.
Suzuki, M., Hirano, S., Otte, K., Schmitz-Hübsch, T., Izumi, M., Tamura, M., Kuroiwa, R., Sugiyama, A., Mori, M., Röhling, H.M., Brandt, A.U., Murata, A., Paul, F. and Kuwabara, S:
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January 2023
Hippocampal GABAergic interneurons and memory.
Tzilivaki, A., Tukker, J.J., Maier, N., Poirazi, P., Sammons, R.P. and Schmitz, D.
Neuron 111
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18 October 2023
Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A., Lahmann, I., Nguyen, L.V.N., Rost, B.R., García-Pérez, A., Lelievre, N., Merritt-Garza, M.E., Phan, H.C, Bassell, G.J., Rossoll, W., Diecke, S., Kunz, S., Schmitz, D. and Gouti, M.
Nature Communications 14
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19 December 2023
Catenin signaling controls phrenic motor neuron development and function during a narrow temporal window.
Vagnozzi, A.N., Moore, M.T., López de Boer, R., Agarwal, A., Zampieri, N., Landmesser, L.T. and Philippidou, P.
Frontiers in Neural Circuits 17
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21 February 2023
The cellular coding of temperature in the mammalian cortex.
Vestergaard, M., Carta, M., Güney, G. and Poulet, J.F.A.
Nature 614
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23 February 2023
The brain's encoding of warm and cool.
Vestergaard, M. and Poulet, J.
Nature
8 February 2023
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Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia.
Wallach, T., Raden, M., Hinkelmann, L., Brehm, M., Rabsch, D., Weidling, H., Krüger, C., Kettenmann, H., Backofen, R. and Lehnardt, S.
Frontiers in Immunology 13
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13 January 2023
Associations of myeloid cells with cellular and humoral responses following vaccinations in patients with neuroimmunological diseases.
Wang, M., Dehlinger, A., Fernández Zapata, C., Golan, M., Gallaccio, G., Sander, L.E., Schlickeiser, S., Kunkel, D., Schmitz-Hübsch, T., Sawitzki, B., Karni, A., Braun, J., Loyal, L., Thiel, A., Bellmann-Strobl, J., Paul, F., Meyer-Arndt, L. and Boettcher, C.
Nature Communications 14
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25 November 2023
Retinal ganglion cell loss is associated with future disability worsening in early relapsing remitting multiple sclerosis.
Wauschkuhn, J., Solorza Buenrostro, G., Aly, L., Asseyer, S., Wicklein, R., Hartberger, J.M., Ruprecht, K., Mühlau, M., Schmitz-Hübsch, T., Chien, C., Berthele, A., Brandt, A.U., Korn, T., Paul, F., Hemmer, B., Zimmermann, H.G. and Knier, B.
European Journal of Neurology 30
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April 2023
Attack adjudication in neuromyelitis optica spectrum disorder: Substantiation of criteria by magnetic resonance imaging and biomarkers in N-MOmentum.
Weinshenker, B.G., Wingerchuk, D.M., Green, A.J., Bennett, J.L., Kim, H.J., Pittock, S.J., Fujihara, K., Paul, F., Cutter, G., Marignier, R., Aktas, O., Hartung, H.P., She, D., Smith, M., Rees, W., Patterson, K., Cimbora, D., Katz, E. and Cree, B.A.
Multiple Sclerosis Journal 29
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July 2023
The OSCAR-MP consensus criteria for quality assessment of retinal optical coherence tomography angiography.
Wicklein, R., Yam, C., Noll, C., Aly, L., Banze, N., Romahn, E.F., Wolf, E., Hemmer, B., Oertel, F.C., Zimmermann, H., Albrecht, P., Ringelstein, M., Baumann, C., Feucht, N., Penkava, J., Havla, J., Gernert, J.A., Mardin, C., Vasileiou, E.S., Van Der Walt, A., Al-Louzi, O., Cabello, S., Vidal-Jordana, A., Krämer, J., Wiendl, H., Preiningerova, J.L., Ciccarelli, O., Garcia-Martin, E., Kana, V., Calabresi, P.A., Paul, F., Saidha, S., Petzold, A., Toosy, A.T. and Knier, B.
Neurology Neuroimmunology & Neuroinflammation 10
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November 2023
Effectiveness of oral prednisone tapering following intravenous methylprednisolone for acute optic neuritis in multiple sclerosis.
Wilf-Yarkoni, A., Feldmann, K., Rubarth, K., Dorsch, E.M., Rust, R., Urman, I., Hellmann, M.A., Friedman, Y., Lotan, I., Bialer, O., Buenrostro, G.S., Zimmermann, H.G., Leutloff, C., Schmitz-Hübsch, T., Paul, F., Asseyer, S. and Stiebel-Kalish, H.
PLoS ONE 18
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7 December 2023
Heat in Germany: Health risks and preventive measures.
Winklmayr, C., Matthies-Wiesler, F., Muthers, S., Buchien, S., Kuch, B., An der Heiden, M. and Mücke, H.G.
Journal of Health Monitoring 8
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6 September 2023
ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution.
Wu, J.Z., Zeziulia, M., Kwon, W., Jentsch, T.J., Grinstein, S. and Freeman, S.A.
Journal of Cell Biology 222
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5 June 2023
Efficient skin interactions of graphene derivatives: challenge, opportunity or both?
Zabihi, F., Tu, Z., Kaessmeyer, S., Schumacher, F., Rancan, F., Kleuser, B., Boettcher, C., Ludwig, K., Plendl, J., Hedtrich, S., Vogt, A. and Haag, R.
Nanoscale Advances 5
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7 November 2023
Association between frailty and free-living walking performance in people with multiple sclerosis.
Zanotto, T., Galperin, I., Mirelman, A., Chen, L., Regev, K., Karni, A., Schmitz-Hübsch, T., Paul, F., Lynch, S.G., Akinwuntan, A.E., Devos, H., Hausdorff, J.M. and Sosnoff, J.J.
Physical Therapy 103
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May 2023
Molecular basis of ClC-6 function and its impairment in human disease.
Zhang, B., Zhang, S., Polovitskaya, M.M., Yi, J., Ye, B., Li, R., Huang, X., Yin, J., Neuens, S., Balfroid, T., Soblet, J., Vens, D., Aeby, A., Li, X., Cai, J., Song, Y., Li, Y., Tartaglia, M., Li, Y., Jentsch, T.J., Yang, M. and Liu, Z.
Science Advances 9
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13 October 2023
Differential ripple propagation along the hippocampal longitudinal axis.
de Filippo, R. and Schmitz, D.
eLife 12
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13 April 2023
The making of a proprioceptor: a tale of two identities.
de Nooij, J.C. and Zampieri, N.
Trends in Neurosciences 46
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December 2023
Increased flexibility of brain dynamics in patients with multiple sclerosis.
von Schwanenflug, N., Koch, S.P., Krohn, S., Broeders, T.A.A., Lydon-Staley, D.M., Bassett, D.S., Schoonheim, M.M., Paul, F. and Finke, C.
Brain Communications 5
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3 May 2023
2022
Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.
Abdelhak, A., Cordano, C., Boscardin, W.J., Caverzasi, E., Kuhle, J., Chan, B., Gelfand, J.M., Yiu, H.H., Oertel, F.C., Beaudry-Richard, A., Condor Montes, S., Oksenberg, J.R., Lario Lago, A., Boxer, A., Rojas-Martinez, J.C., Elahi, F.M., Chan, J.R. and Green, A.J.
Journal of Neurology Neurosurgery and Psychiatry 93
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12 August 2022
Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.
Abdelhak, A., Solomon, I., Montes, S.C., Saias, A., Cordano, C., Asken, B., Fonseca, C., Oertel, F.C., Arfanakis, K., Staffaroni, A.M., Kramer, J.H., Geschwind, M., Miller, B.L., Elahi, F.M. and Green, A.J.
Alzheimer's & Dementia: Diagnosis Assessment & Disease Monitoring 14
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2022
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H., Flórez, A.F., Kreth, S., Brückner, L.M., Yildiz, U., Gartlgruber, M., Odoni, D.I., Poschet, G., Garbowicz, K., Shao, C., Klein, C., Meier, J., Zeisberger, P., Nadler-Holly, M., Ziehm, M., Paul, F., Burhenne, J., Bell, E., Shaikhkarami, M., Würth, R., Stainczyk, S.A., Wecht, E.M., Kreth, J., Büttner, M., Ishaque, N., Schlesner, M., Nicke, B., Stresemann, C., Llamazares-Prada, M., Reiling, J.H., Fischer, M., Amit, I., Selbach, M., Herrmann, C., Wölfl, S., Henrich, K.O., Höfer, T., Trumpp, A. and Westermann, F.
Nature Cancer 3
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28 April 2022
Different impact of gadopentetate and gadobutrol on inflammation-promoted retention and toxicity of gadolinium within the mouse brain.
Anderhalten, L., Silva, R.V., Morr, A., Wang, S., Smorodchenko, A., Saatz, J., Traub, H., Mueller, S., Boehm-Sturm, P., Rodriguez-Sillke, Y., Kunkel, D., Hahndorf, J., Paul, F., Taupitz, M., Sack, I. and Infante-Duarte, C.
Investigative Radiology 57
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1 October 2022
Impaired motion perception is associated with functional and structural visual pathway damage in multiple sclerosis and neuromyelitis optica spectrum disorders.
Ayadi, N., Oertel, F.C., Asseyer, S., Rust, R., Duchow, A., Kuchling, J., Bellmann-Strobl, J., Ruprecht, K., Klistorner, A., Brandt, A.U., Paul, F. and Zimmermann, H.G.
Multiple Sclerosis Journal 28
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April 2022
A naked eye-invisible ratiometric fluorescent microneedle tattoo for real-time monitoring of inflammatory skin conditions.
Babity, S., Couture, F., Campos, E.V.R., Hedtrich, S., Hagen, R., Fehr, D., Bonmarin, M. and Brambilla, D.
Advanced Healthcare Materials 11
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March 2022
Anatomical and functional visual network patterns in progressive multiple sclerosis.
Backner, Y., Zamir, S., Petrou, P., Paul, F., Karussis, D. and Levin, N.
Human Brain Mapping 43
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1 April 2022
RS-FISH: precise, interactive, fast, and scalable FISH spot detection.
Bahry, E., Breimann, L., Zouinkhi, M., Epstein, L., Kolyvanov, K., Mamrak, N., King, B., Long, Xi, Harrington, K.I.S., Lionnet, T. and Preibisch, S.
Nature Methods 19
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December 2022
Microglia form satellites with different neuronal subtypes in the adult murine central nervous system.
Bakina, O., Kettenmann, H. and Nolte, C.
Journal of Neuroscience Research 100
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April 2022
Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A., Gündüz, I.B., Franke, V., Uyar, B. and Akalin, A.
Cancers 14
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15 November 2022
Transcriptome analysis reveals high tumor heterogeneity with respect to re-activation of stemness and proliferation programs.
Baranovsky, A., Ivanov, T., Granovskaya, M., Papatsenko, D. and Pervouchine, D.D.
PLoS ONE 17
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19 May 2022
Sexual dimorphism in extracellular matrix composition and viscoelasticity of the healthy and inflamed mouse brain.
Batzdorf, C.S., Morr, A.S., Bertalan, G., Sack, I., Silva, R.V. and Infante-Duarte, C.
Biology 11
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31 January 2022
SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G., Blume, A., Demirel, F.G., Bulut, S., Popp, O., Mertins, P. and Tursun, B.
Biotechniques 73
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June 2022
Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G., Popp, O., Mertins, P. and Tursun, B.
Biotechniques 72
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May 2022
Human primary muscle stem cells regenerate injured urethral sphincter in athymic rats.
Bekele, B.M., Schöwel-Wolf, V., Kieshauer, J., Marg, A., Busjahn, A., Davis, S., Nugent, G., Ebert, A.K. and Spuler, S.
Animal Models and Experimental Medicine 5
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October 2022
In memoriam: Stephen B. McMahon, PhD, FMedSci December 21, 1954 to October 9, 2021.
Bennett, D.L.H., Bradbury, E.J., Lewin, G.R. and Rice, A.S.C.
Pain 163
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March 2022
Association between B-cell depletion and attack risk in neuromyelitis optica spectrum disorder: An exploratory analysis from N-MOmentum, a double-blind, randomised, placebo-controlled, multicentre phase 2/3 trial.
Bennett, J.L., Aktas, O., Rees, W.A., Smith, M.A., Gunsior, M., Yan, L., She, D., Cimbora, D., Pittock, S.J., Weinshenker, B.G., Paul, F., Marignier, R., Wingerchuk, D., Cutter, G., Green, A., Hartung, H.P., Kim, H.J., Fujihara, K., Levy, M., Katz, E. and Cree, B.A.C.
EBioMedicine 86
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December 2022
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation.
Blassberg, R., Patel, H., Watson, T., Gouti, M., Metzis, V., Delás, M.J. and Briscoe, J.
Nature Cell Biology 24
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May 2022
Impact of dietary intervention on serum neurofilament light chain in multiple sclerosis.
Bock, M., Steffen, F., Zipp, F. and Bittner, S.
Neurology Neuroimmunology & Neuroinflammation 9
(1): e1102.
January 2022
Tissue engineering for the diaphragm and its various therapeutic possibilities - a systematic review.
Boehm, A.K., Hillebrandt, K.H., Dziodzio, T., Krenzien, F., Neudecker, J., Spuler, S., Pratschke, J., Sauer, I.M. and Andreas, M.N.
Advanced Therapeutics 5
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18 August 2022
Central stress processing, T-cell responsivity to stress hormones, and disease severity in multiple sclerosis.
Brasanac, J., Hetzer, S., Asseyer, S., Kuchling, J., Bellmann-Strobl, J., Ritter, K., Gamradt, S., Scheel, M., Haynes, J.D., Brandt, A.U., Paul, F., Gold, S.M. and Weygandt, M.
Brain Communications 4
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4 April 2022
Immune signature of multiple sclerosis-associated depression.
Brasanac, J., Ramien, C., Gamradt, S., Tänzer, A., Glau, L., Ritter, K., Patas, K., Agorastos, A., Wiedemann, K., Demiralay, C., Fischer, F., Otte, C., Bellmann-Strobl, J., Friese, M.A., Tolosa, E., Paul, F., Heesen, C., Weygandt, M. and Gold, S.M.
Brain Behavior and Immunity 100
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February 2022
The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L., Morao, A.K., Kim, J., Jimenez, D.S., Maryn, N., Bikkasani, K., Carrozza, M.J., Albritton, S.E., Kramer, M., Street, L.A., Cerimi, K., Schumann, V.F., Bahry, E., Preibisch, S., Woehler, A. and Ercan, S.
Journal of Cell Science 135
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January 2022
Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis.
Brune, S., Høgestøl, E.A., de Rodez Benavent, S.A., Berg-Hansen, P., Beyer, M.K., Leikfoss, I.S., Bos, S.D., Sowa, P., Brunborg, C., Andorra, M., Pulido Valdeolivas, I., Asseyer, S., Brandt, A., Chien, C., Scheel, M., Blennow, K., Zetterberg, H., Kerlero de Rosbo, N., Paul, F., Uccelli, A., Villoslada, P., Berge, T. and Harbo, H.F.
Multiple Sclerosis Journal 28
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October 2022
The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.
Buffenstein, R., Amoroso, V., Andziak, B., Avdieiev, S., Azpurua, J., Barker, A.J., Bennett, N.C., Brieño-Enríquez, M.A., Bronner, G.N., Coen, C., Delaney, M.A., Dengler-Crish, C.M., Edrey, Y.H., Faulkes, C.G., Frankel, D., Friedlander, G., Gibney, P.A., Gorbunova, V., Hine, C., Holmes, M.M., Jarvis, J.U.M., Kawamura, Y., Kutsukake, N., Kenyon, C., Khaled, W.T., Kikusui, T., Kissil, J., Lagestee, S., Larson, J., Lauer, A., Lavrenchenko, L.A., Lee, A., Levitt, J.B., Lewin, G.R., Lewis Hardell, K.N., Lin, T.D., Mason, M.J., McCloskey, D., McMahon, M., Miura, K., Mogi, K., Narayan, V., O'Connor, T.P., Okanoya, K., O'Riain, M.J., Park, T.J., Place, N.J., Podshivalova, K., Pamenter, M.E., Pyott, S.J., Reznick, J., Ruby, J.G., Salmon, A.B., Santos-Sacchi, J., Sarko, D.K., Seluanov, A., Shepard, A., Smith, M., Storey, K.B., Tian, X., Vice, E.N., Viltard, M., Watarai, Ak., Wywial, E., Yamakawa, M., Zemlemerova, E.D., Zions, M. and Smith, E.S.J.
Biological Reviews 97
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February 2022
The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression.
Bujanic, L., Shevchuk, O., von Kügelgen, N., Kalinina, A., Ludwik, K., Koppstein, D., Zerna, N., Sickmann, A. and Chekulaeva, M.
RNA 28
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May 2022
Immune competence and spleen size scale with colony
status in the naked mole-rat.
Bégay, V., Cirovic, B., Barker, A.J., Klopffleisch, R., Hart, D.W., Bennett, N.C. and Lewin, G.R.
Open Biology 12
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6 April 2022
Organoids as tools for fundamental discovery and translation - a Keystone Symposia report.
Cable, J., Lutolf, M.P., Fu, J., Park, S.E., Apostolou, A., Chen, S., Song, C.J., Spence, J.R., Liberali, P., Lancaster, M., Meier, A.B., Pek, N.M.Q., Wells, J.M., Capeling, M.M., Uzquiano, A., Musah, S., Huch, M., Gouti, M., Hombrink, P., Quadrato, G. and Urenda, J.P.
Annals of the New York Academy of Sciences 1518
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December 2022
Seasonal variation in attacks of neuromyelitis optica spectrum disorders and multiple sclerosis: evaluation of 794 attacks from a nationwide registry in Argentina.
Carnero Contentti, E., Lopez, P.A., Pettinicchi, J.P., Criniti, J., Pappolla, A., Miguez, J., Patrucco, L., Cristiano, E., Liwacki, S., Tkachuk, V., Balbuena, M.E., Vrech, C., Deri, N., Correale, J., Marrodan, M., Ysrraelit, M.C., Leguizamon, F., Luetic, G., Menichini, M.L., Tavolini, D., Mainella, C., Zanga, G., Burgos, M., Hryb, J., Barboza, A., Lazaro, L., Alonso, R., Fernández Liguori, N., Nadur, D., Chercoff, A., Alonso Serena, M., Caride, A., Paul, F. and Rojas, J.I.
Multiple Sclerosis and Related Disorders 58
: 103466.
February 2022
Association of maintenance intravenous immunoglobulin with prevention of relapse in adult myelin oligodendrocyte glycoprotein antibody-associated disease.
Chen, J.J., Huda, S., Hacohen, Y., Levy, M., Lotan, I., Wilf-Yarkoni, A., Stiebel-Kalish, H., Hellmann, M.A., Sotirchos, E.S., Henderson, A.D., Pittock, S.J., Bhatti, M.T., Eggenberger, E.R., Di Nome, M., Kim, H.J., Kim, S.H., Saiz, A., Paul, F., Dale, R.C., Ramanathan, S., Palace, J., Camera, V., Leite, M.I., Lam, B.L., Bennett, J.L., Mariotto, S., Hodge, D., Audoin, B., Maillart, E., Deschamps, R., Pique, J., Flanagan, E.P. and Marignier, R.
JAMA Neurology 79
(5): 518-525.
1 May 2022
OCT retinal nerve fiber layer thickness differentiates acute optic neuritis from MOG antibody-associated disease and Multiple Sclerosis: RNFL thickening in acute optic neuritis from MOGAD vs MS.
Chen, J.J., Sotirchos, E.S., Henderson, A.D., Vasileiou, E.S., Flanagan, E.P., Bhatti, M.T., Jamali, S., Eggenberger, E.R., Dinome, M., Frohman, L.P., Arnold, A.C., Bonelli, L., Seleme, N., Mejia-Vergara, A.J., Moss, H.E., Padungkiatsagul, T., Stiebel-Kalish, H., Lotan, I., Hellmann, M.A., Hodge, D., Oertel, F.C., Paul, F., Saidha, S., Calabresi, P.A. and Pittock, S.J.
Multiple Sclerosis and Related Disorders 58
: 103525.
February 2022
Prediction of high and low disease activity in early MS patients using multiple kernel learning identifies importance of lateral ventricle intensity.
Chien, C., Seiler, M., Eitel, F., Schmitz-Hübsch, T., Paul, F. and Ritter, K.
Multiple Sclerosis Journal Experimental Translational and Clinical 8
(3): 20552173221109770.
1 July 2022
Motor signature of autism spectrum disorder in adults without intellectual impairment.
Cho, A.B., Otte, K., Baskow, I., Ehlen, F., Maslahati, T., Mansow-Model, S., Schmitz-Hübsch, T., Behnia, B. and Roepke, S.
Scientific Reports 12
(1): 7670.
10 May 2022
Differences in age-related retinal and cortical atrophy rates in multiple sclerosis.
Cordano, C., Nourbakhsh, B., Yiu, H.H., Papinutto, N., Caverzasi, E., Abdelhak, A., Oertel, F.C., Beaudry-Richard, A., Santaniello, A., Sacco, S., Bennett, D.J., Gomez, A., Sigurdson, C.J., Hauser, S.L., Magliozzi, R., Cree, B.A.C., Henry, R.G. and Green, A.J.
Neurology 99
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11 October 2022
Reply to "Interpretation of longitudinal changes of the inner nuclear layer in MS".
Cordano, C., Yiu, H.H., Abdelhak, A., Beaudry-Richard, A., Oertel, F.C. and Green, A.J.
Annals of Neurology 92
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July 2022
Retinoids are not linked to risk of multiple sclerosis: a Danish nationwide cohort study.
Cortes-Figueiredo, F., Nielsen, N.M., Stenager, E., Paul, F., Hallas, J. and Kristensen, K.B.
European Journal of Neurology 2
(1): 247-256.
18 January 2022
SPFH protein cage - one ring to rule them all.
Daumke, O. and Lewin, G.R.
Cell Research 32
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February 2022
Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S., Company, C., Song, K., Lowenstein, E.D., Riedel, L., Birchmeier, C., Gargiulo, G. and Zampieri, N.
Nature Communications 13
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11 November 2022
Identifying tumor cells at the single-cell level using machine learning.
Dohmen, J., Baranovskii, A., Ronen, J., Uyar, B., Franke, V. and Akalin, A.
Genome Biology 23
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30 May 2022
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H., Pusch, F., Bei, Y., von Stebut, J., Ibáñez, G., Guillan, K., Imami, K., Gürgen, D., Rolff, J., Helmsauer, K., Meyer-Liesener, S., Timme, N., Bardinet, V., Chamorro González, R., MacArthur, I.C., Chen, C.Y., Schulz, J., Wengner, A.M., Furth, C., Lala, B., Eggert, A., Seifert, G., Hundsoerfer, P., Kirchner, M., Mertins, P., Selbach, M., Lissat, A., Dubois, F., Horst, D., Schulte, J.H., Spuler, S., You, D., Dela Cruz, F., Kung, A.L., Haase, K., Di Virgilio, M., Scheer, M., Ortiz, M.V. and Henssen, A.G.
Nature Communications 13
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25 July 2022
Gender differences in perceptions and attitudes of medical students towards neurosurgery: a german nationwide survey.
Efe, I.E., Aliyeva, I., Beyaztas, D., Swiatek, V.M., Esene, I.N. and Abdulrauf, S.I.
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July 2022
Stammzelltherapien für Muskeldystrophien.
Escobar, H.
BIOspektrum 28
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September 2022
One gene - two proteins: the C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria.
Fasciani, I., Petragnano, F., Wang, Z., Edwards, R., Telugu, N., Pietrantoni, I., Zauber, H., Rossi, M., Zabel, U., Grieben, M., Terzenidou, M.E., Di Gregorio, J., Pellegrini, C., Santini, S., Taddei, A.R., Poehl, B., Aringhieri, S., Aloisi, G., Marampon, F., Roman, A., Diecke, S., Flati, V., Giorgi, F., Amicarelli, F., Tobin, A.B., Scarselli, M., Tokatlidis, K., Lohse, M.J., Maggio, R. and Annibale, P.
bioRxiv
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26 February 2022
Editorial: The long road to building a head: smooth travels and accidents on the journey from patterning via morphogenesis to phenotype.
Feistel, K., Hammes, A. and Sela-Donenfeld, D.
Frontiers in Cell and Developmental Biology 10
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25 April 2022
A similarity scaling approach for organ-on-chip devices.
Feng, J.J. and Hedtrich, S.
Lab on a Chip 22
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7 October 2022
Calcium-permeable channelrhodopsins for the photocontrol of calcium signalling.
Fernandez Lahore, R.G., Pampaloni, N.P., Schiewer, E., Heim, M.M., Tillert, L., Vierock, J., Oppermann, J., Walther, J., Schmitz, D., Owald, D., Plested, A.J.R., Rost, B.R. and Hegemann, P.
Nature Communications 13
(1): 7844.
21 December 2022
Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer's disease.
Fernández Zapata, C., Giacomello, G., Spruth, E.J., Middeldorp, J., Gallaccio, G., Dehlinger, A., Dames, C., Leman, J.K.H., van Dijk, R.E., Meisel, A., Schlickeiser, S., Kunkel, D., Hol, E.M., Paul, F., Parr, M.K., Priller, J. and Böttcher, C.
Nature Communications 13
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23 November 2022
Subcortical volumes as early predictors of fatigue in multiple sclerosis.
Fleischer, V., Ciolac, D., Gonzalez-Escamilla, G., Grothe, M., Strauss, S., Molina Galindo, L.S., Radetz, A., Salmen, A., Lukas, C., Klotz, L., Meuth, S.G., Bayas, A., Paul, F., Hartung, H.P., Heesen, C., Stangel, M., Wildemann, B., Bergh, F.T., Tackenberg, B., Kümpfel, T., Zettl, U.K., Knop, M., Tumani, H., Wiendl, H., Gold, R., Bittner, S., Zipp, F., Groppa, S. and Muthuraman, M.
Annals of Neurology 91
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February 2022
Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised, controlled, open-label, phase 3b trial.
Foley, J.F., Defer, G., Ryerson, L.Z., Cohen, J.A., Arnold, D.L., Butzkueven, H., Cutter, G., Giovannoni, G., Killestein, J., Wiendl, H., Smirnakis, K., Xiao, S., Kong, G., Kuhelj, R. and Campbell, N.
Lancet Neurology 21
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July 2022
Therapy switches in fingolimod-treated patients with multiple sclerosis: long-term experience from the German MS Registry.
Frahm, N., Fneish, F., Ellenberger, D., Flachenecker, P., Paul, F., Warnke, C., Kleinschnitz, C., Parciak, T., Krefting, D., Hellwig, K., Haas, J., Rommer, P.S., Stahmann, A. and Zettl, U.K.
Neurology and Therapy 11
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March 2022
CTGF/CCN2 has a possible detrimental role in the inflammation and the remyelination failure in the early stages of multiple sclerosis.
Fuchs, L., Mausner-Fainberg, K., Luban, A., Asseyer, S.E., Golan, M., Benhamou, M., Volovitz, I., Regev, K., Vigiser, I., Piura, Y., Kolb, H., Paul, F. and Karni, A.
Journal of Neuroimmunology 371
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15 October 2022
The role of intraspinal sensory neurons in the control of quadrupedal locomotion.
Gerstmann, K., Jurčić, N., Blasco, E., Kunz, S., de Almeida Sassi, F., Wanaverbecq, N. and Zampieri, N.
Current Biology 32
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6 June 2022
Isotopic tracing of glucose metabolites in human monocytes to assess changes in inflammatory conditions.
Giacomello, G., Böttcher, C. and Parr, M.K.
STAR Protocols 3
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16 December 2022
Structure-function correlates of vision loss in neuromyelitis optica spectrum disorders.
Gigengack, N.K., Oertel, F.C., Motamedi, S., Bereuter, C., Duchow, A., Rust, R., Bellmann‑Strobl, J., Ruprecht, K., Schmitz-Hübsch, T., Paul, F., Brandt, A.U. and Zimmermann, H.G.
Scientific Reports 12
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20 October 2022
Preclinical testing of dendritic core-multishell nanoparticles in inflammatory skin equivalents.
Graff, P., Hönzke, S., Joshi, A.A., Yealland, G., Fleige, E., Unbehauen, M., Schäfer-Korting, M., Hocke, A., Haag, R. and Hedtrich, S.
Molecular Pharmaceutics 19
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6 June 2022
Leveraging visual outcome measures to advance therapy development in neuroimmunologic disorders.
Graves, J.S., Oertel, F.C., Van der Walt, A., Collorone, S., Sotirchos, E.S., Pihl-Jensen, G., Albrecht, P., Yeh, E.A., Saidha, S., Frederiksen, J., Newsome, S.D. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 9
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March 2022
Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.
Greco, T.M., Secker, C., Silva Ramos, E., Federspiel, J.D., Liu, J.P., Perez, A.M., Al-Ramahi, I., Cantle, J.P., Carroll, J.B., Botas, J., Zeitlin, S.O., Wanker, E.E. and Cristea, I.M.
Cell Systems 13
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22 April 2022
Influence of nanogel amphiphilicity on dermal delivery: balancing surface hydrophobicity and network rigidity.
Gruber, Al., Joshi, A.A., Graff, P., Cuéllar-Camacho, J.L., Hedtrich, S. and Klinger, D.
Biomacromolecules 23
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10 January 2022
Statins aggravate the risk of insulin resistance in human muscle.
Grunwald, S.A., Haafke, S., Grieben, U., Kassner, U., Steinhagen-Thiessen, E. and Spuler, S.
International Journal of Molecular Sciences 23
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21 February 2022
Cell-type specific inhibition controls the high-frequency oscillations in the medial entorhinal cortex.
Gurgenidze, S., Bäuerle, P., Schmitz, D., Vida, I., Gloveli, T. and Dugladze, T.
International Journal of Molecular Sciences 23
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15 November 2022
Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS).
Haffke, M., Freitag, H., Rudolf, G., Seifert, M., Doehner, W., Scherbakov, N., Hanitsch, L., Wittke, K., Bauer, S., Konietschke, F., Paul, F., Bellmann-Strobl, J., Kedor, C., Scheibenbogen, C. and Sotzny, F.
Journal of Translational Medicine 20
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22 March 2022
Long-term connectome analysis reveals reshaping of visual, spatial networks in a model with vascular dementia features.
Hall, G.R., Boehm-Sturm, P., Dirnagl, U., Finke, C., Foddis, M., Harms, C., Koch, S.P., Kuchling, J., Madan, C.R., Mueller, S., Sassi, C., Sotiropoulos, S.N., Trueman, R.C., Wallis, M.D., Yildirim, F. and Farr, T.D.
Stroke 53
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May 2022
A comparative study of graph matching algorithms in computer vision.
Haller, S., Feineis, L., Hutschenreiter, L., Bernard, F., Rother, C., Kainmüller, D., Swoboda, P. and Savchynskyy, B.
Lecture Notes in Computer Science 13683
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2022
A critical period of translational control during brain development at codon resolution.
Harnett, D., Ambrozkiewicz, M.C., Zinnall, U., Rusanova, A., Borisova, E., Drescher, A.N., Couce-Iglesias, M., Villamil, G., Dannenberg, R., Imami, K., Münster-Wandowski, A., Fauler, B., Mielke, T., Selbach, M., Landthaler, M., Spahn, C.M.T., Tarabykin, V., Ohler, U. and Kraushar, M.L.
Nature Structural & Molecular Biology 29
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December 2022
Pseudocholinesterase as a biomarker for untreated Wilson's disease.
Hefter, H., Arslan, M., Kruschel, T.S., Novak, M., Rosenthal, D., Meuth, S.G., Albrecht, P., Hartmann, C.J. and Samadzadeh, S.
Biomolecules 12
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December 2022
In vivo stiffness of multiple sclerosis lesions is similar to that of normal-appearing white matter.
Herthum, H., Hetzer, S., Scheel, M., Shahryari, M., Braun, J., Paul, F. and Sack, I.
Acta Biomaterialia 138
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15 January 2022
Temperature elevations can induce switches to homoclinic action potentials that alter neural encoding and synchronization.
Hesse, J., Schleimer, J.H., Maier, N., Schmitz, D. and Schreiber, S.
Nature Communications 13
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8 July 2022
Mathematical and bioinformatic tools for cell tracking.
Hirsch, P., Epstein, L. and Guignard, L.
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Uncoupling the excitatory amino acid transporter 2 from its C-terminal interactome restores synaptic glutamate clearance at corticostriatal synapses and alleviates mutant huntingtin-induced hypokinesia.
Hirschberg, S., Dvorzhak, A., Rasooli-Nejad, S.M.A., Angelov, S., Kirchner, M., Mertins, P., Lättig-Tünnemann, G., Harms, C., Schmitz, D. and Grantyn, R.
Frontiers in Cellular Neuroscience 15
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31 January 2022
Small, cationic antifungal proteins from filamentous fungi inhibit Candida albicans growth in 3D skin infection models.
Holzknecht, J., Dubrac, S., Hedtrich, S., Galgóczy, L. and Marx, F.
Microbiology Spectrum 10
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June 2022
Microglia/macrophage derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model.
Huang, Y., Motta, E., Nanvuma, C., Kuhrt, L.D., Yuan, Y., Xia, P., Lubas, M., Zhu, S., Schnauss, M., Qazi, N., Hu, F., Zhang, H., Lei, T., Synowitz, M., Flüh, C. and Kettenmann, H.
Cell Reports 39
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12 April 2022
Once upon a dish: the next frontier in engineering multicellular systems.
Huch, M. and Gouti, M.
Development 149
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15 October 2022
Rationale and design of the prevention of paclitaxel-related neurological side effects with lithium trial – Protocol of a multicenter, randomized, double-blind, placebo-controlled proof-of-concept phase-2 clinical trial.
Huehnchen, P., Bangemann, N., Lischewski, S., Märschenz, S., Paul, F., Schmitz-Hübsch, T., Blohmer, J.U., Eberhardt, C., Rauch, G., Flöel, A., Adam, S., Schwenkenbecher, P., Meinhold-Heerlein, I., Hoffmann, O., Ziemssen, T., Endres, M. and Boehmerle, W.
Frontiers in Medicine 9
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11 August 2022
Fusion moves for graph matching.
Hutschenreiter, L., Haller, S., Feineis, L., Rother, C., Kainmüller, D. and Savchynskyy, B.
In: 2021 IEEE/CVF International Conference on Computer Vision (ICCV), 10-17 Oct 2021, Montreal, QC, Canada.
28 February 2022
CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage.
Hyun, J.W., Kim, Y., Kim, K.H., Kim, S.H., Olesen, M.N., Asgari, N., Siritho, S., Paul, F. and Kim, H.J.
Journal of Neuroinflammation 19
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12 April 2022
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke, K., Obermayer, B., Mache, C., Fathykova, D., Kessler, M., Dökel, S., Wyler, E., Baumgardt, M., Löwa, A., Hoffmann, K., Graff, P., Schulze, J., Mieth, M., Hellwig, K., Demir, Z., Biere, B., Brunotte, L., Mecate-Zambrano, A., Bushe, J., Dohmen, M., Hinze, C., Elezkurtaj, S., Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Schmidt-Ott, K.M., Busch, J., Klauschen, F., Horst, D., Radbruch, H., Radke, J., Heppner, F., Corman, V.M., Niemeyer, D., Müller, M.A., Goffinet, C., Mothes, R., Pascual-Reguant, A., Hauser, A.E., Beule, D., Landthaler, M., Ludwig, S., Suttorp, N., Witzenrath, M., Gruber, A.D., Drosten, C., Sander, L.E., Wolff, T., Hippenstiel, S. and Hocke, A.C.
European Respiratory Journal 60
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1 December 2022
Costs and health-related quality of life in patients with NMO spectrum disorders and MOG-antibody-associated disease: CHANCE(NMO) study.
Hümmert, M.W., Schöppe, L.M., Bellmann-Strobl, J., Siebert, N., Paul, F., Duchow, A., Pellkofer, H., Kümpfel, T., Havla, J., Jarius, S., Wildemann, B., Berthele, A., Bergh, F.T., Pawlitzki, M., Klotz, L., Kleiter, I., Stangel, M., Gingele, S., Weber, M.S., Faiss, J.H., Pul, R., Walter, A., Zettl, U., Senel, M., Stellmann, J.P., Häußler, V., Hellwig, K., Ayzenberg, I., Aktas, O., Ringelstein, M., Schreiber-Katz, O. and Trebst, C.
Neurology 98
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15 March 2022
Automated detection and localization of synaptic vesicles in electron microscopy images.
Imbrosci, B., Schmitz, D. and Orlando, M.
eNeuro 9
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January 2022
Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients.
Jarius, S., Pache, F., Körtvelyessy, P., Jelčić, I., Stettner, M., Franciotta, D., Keller, E., Neumann, B., Ringelstein, M., Senel, M., Regeniter, A., Kalantzis, R., Willms, J.F., Berthele, A., Busch, M., Capobianco, M., Eisele, A., Reichen, I., Dersch, R., Rauer, S., Sandner, K., Ayzenberg, I., Gross, C.C., Hegen, H., Khalil, M., Kleiter, I., Lenhard, T., Haas, J., Aktas, O., Angstwurm, K., Kleinschnitz, C., Lewerenz, J., Tumani, H., Paul, F., Stangel, M., Ruprecht, K. and Wildemann, B.
Journal of Neuroinflammation 19
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20 January 2022
Modular deep neural networks for automatic quality control of retinal optical coherence tomography scans.
Kauer-Bonin, J., Yadav, S.K., Beckers, I., Gawlik, K., Motamedi, S., Zimmermann, H.G., Kadas, E.M., Haußer, F., Paul, F. and Brandt, A.U.
Computers in Biology and Medicine 141
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1 February 2022
A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity.
Kedor, C., Freitag, H., Meyer-Arndt, L., Wittke, K., Hanitsch, L.G., Zoller, T., Steinbeis, F., Haffke, M., Rudolf, G., Heidecker, B., Bobbert, T., Spranger, J., Volk, H.D., Skurk, C., Konietschke, F., Paul, F., Behrends, U., Bellmann-Strobl, J. and Scheibenbogen, C.
Nature Communications 13
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30 August 2022
Normative data and conversion equation for spectral-domain optical coherence tomography in an international healthy control cohort.
Kenney, R., Liu, M., Hasanaj, L., Joseph, B., Al-Hassan, A.A., Balk, L., Behbehani, R., Brandt, A.U., Calabresi, P.A., Frohman, E.M., Frohman, T., Havla, J., Hemmer, B., Jiang, H., Knier, B., Korn, T., Leocani, L., Martínez-Lapiscina, E.H., Papadopoulou, A., Paul, F., Petzold, A., Pisa, M., Villoslada, P., Zimmermann, H., Ishikawa, H., Schuman, J.S., Wollstein, G., Chen, Y., Saidha, S., Thorpe, L.E., Galetta, S.L. and Balcer, L.J.
Journal of Neuro-Ophthalmology 42
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December 2022
The role of optical coherence tomography criteria and machine learning in multiple sclerosis and optic neuritis diagnosis.
Kenney, R.C., Liu, M., Hasanaj, L., Joseph, B., Al-Hassan, A.A., Balk, L.J., Behbehani, R., Brandt, A., Calabresi, P.A., Frohman, E., Frohman, T.C., Havla, J., Hemmer, B., Jiang, H., Knier, B., Korn, T., Leocani, L., Martinez-Lapiscina, E.H., Papadopoulou, A., Paul, F., Petzold, A., Pisa, M., Villoslada, P., Zimmermann, H., Thorpe, L.E., Ishikawa, H., Schuman, J.S., Wollstein, G., Chen, Y., Saidha, S., Galetta, S. and Balcer, L.J.
Neurology 99
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13 September 2022
Glial cells: neuroglia.
Kettenmann, H. and Verkhratsky, A.
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Springer Nature, Cham, 825-860.
ISBN 978-3-030-88831-2
2022
SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta.
Kirchenwitz, M., Stahnke, S., Prettin, S., Borowiak, M., Menke, L., Sieben, C., Birchmeier, C., Rottner, K., Stradal, T.E.B. and Steffen, A.
Cells 11
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16 May 2022
Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve.
Kleineidam, L., Wolfsgruber, S., Weyrauch, A.S., Zulka, L.E., Forstmeier, S., Roeske, S., van den Bussche, H., Kaduszkiewicz, H., Wiese, B., Weyerer, S., Werle, J., Fuchs, A., Pentzek, M., Brettschneider, C., König, H.H., Weeg, D., Bickel, H., Luppa, M., Rodriguez, F.S., Freiesleben, S.D., Erdogan, S., Unterfeld, C., Peters, O., Spruth, E.J., Altenstein, S., Lohse, A., Priller, J., Fliessbach, K., Kobeleva, X., Schneider, A., Bartels, C., Schott, B.H., Wiltfang, J., Maier, F., Glanz, W., Incesoy, E.I., Butryn, M., Düzel, E., Buerger, K., Janowitz, D., Ewers, M., Rauchmann, B.S., Perneczky, R., Kilimann, I., Görß, D., Teipel, S., Laske, C., Munk, M.H.J., Spottke, A., Roy, N., Brosseron, F., Heneka, M.T., Ramirez, A., Yakupov, R., Scherer, M., Maier, W., Jessen, F., Riedel-Heller, S.G. and Wagner, M.
Frontiers in Psychology 13
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8 December 2022
Overnight unilateral withdrawal of thalamic deep brain stimulation to identify reversibility of gait disturbances.
Kroneberg, D., Al-Fatly, B., Schmitz-Hübsch, T., Gandor, F., Gruber, D., Ebersbach, G., Horn, A. and Kühn, A.A.
Experimental Neurology 355
: 114135.
September 2022
Statistical analysis in the German National Cohort (NAKO) - specific aspects and general recommendations.
Kuss, O., Becher, H., Wienke, A., Ittermann, T., Ostrzinski, S., Schipf, S., Schmidt, C.O., Leitzmann, M., Pischon, T., Krist, L., Roll, S., Sand, M., Pohlabeln, H., Rach, S., Jöckel, K.H., Stang, A., Mueller, U.A., Werdecker, A., Westerman, R., Greiser, K.H. and Michels, K.B.
European Journal of Epidemiology 37
(4): 429-436.
April 2022
Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling.
Langer, H.T., West, D., Senden, J., Spuler, S., van Loon, L.J.C. and Baar, K.
Scientific Reports 12
(1): 7553.
9 May 2022
Mafa-dependent GABAergic activity promotes mouse neonatal apneas.
Lecoin, L., Dempsey, B., Garancher, A., Bourane, S., Ruffault, P.L., Morin-Surun, M.P., Rocques, N., Goulding, M., Eychène, A., Pouponnot, C., Fortin, G. and Champagnat, J.
Nature Communications 13
(1): 3284.
7 June 2022
Spatio-temporal, optogenetic control of gene expression in organoids.
Legnini, I., Emmenegger, L., Zappulo, A., Wurmus, R., Oliveras Martinez, A., Cerda Jara, C., Boltengagen, A., Hessler, T., Mastrobuoni, G., Rybak-Wolf, A., Kempa, S., Zinzen, R.P., Woehler, A. and Rajewsky, N.
bioRxiv
: 2021.09.26.461850v3.
9 February 2022
Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M., Wang, Y.H., Kaufmann, U., Gerbeth, L., Sand, A., Brunkhorst, M., Weidner, P., Ziegler, J.F., Böttcher, C., Schlickeiser, S., Fernández, C., Yamashita, M., Stauderman, K., Sun, K., Kunkel, D., Prakriya, M., Sanders, A.D., Siegmund, B., Feske, S. and Weidinger, C.
EMBO Molecular Medicine
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2 August 2022
Fly Cell Atlas: a single-nucleus transcriptomic atlas of the adult fruit fly.
Li, H., Janssens, J., De Waegeneer, M., Kolluru, S.S., Davie, K., Gardeux, V., Saelens, W., David, F.P.A., Brbić, M., Spanier, K., Leskovec, J., McLaughlin, C.N., Xie, Q., Jones, R.C., Brueckner, K., Shim, J., Tattikota, S.G., Schnorrer, F., Rust, K., Nystul, T.G., Carvalho-Santos, Zi., Ribeiro, C., Pal, S., Mahadevaraju, S., Przytycka, T.M., Allen, A.M., Goodwin, S.F., Berry, C.W., Fuller, M.T., White-Cooper, H., Matunis, E.L., DiNardo, S., Galenza, A., O'Brien, L.E., Dow, J.A.T., Jasper, H., Oliver, B., Perrimon, N., Deplancke, B., Quake, S.R., Luo, L. and Aerts, S.
Science 375
(6584): eabk2432.
4 March 2022
Neuroophthalmologische Präsentation der Retrobulbärneuritis im Rahmen der Myelin-Oligodendrozyten-Glykoprotein-Antikörper-assoziierten Erkrankung [Neuro-ophthalmological presentation of optic neuritis in myelin oligodendrocyte glycoprotein antibody-associated disease].
Lin, T.Y., Asseyer, S., Buenrostro, G.S., Feldmann, K., Hamann, S., Paul, F. and Zimmermann, H.G.
Klinische Monatsblatter fur Augenheilkunde 239
(11): 1305-1314.
21 November 2022
Serum glial fibrillary acidic protein correlates with retinal structural damage in aquaporin-4 antibody positive neuromyelitis optica spectrum disorder.
Lin, T.Y., Schindler, P., Grittner, U., Oertel, F.C., Lu, A., Motamedi, S., Yadav, S.K., Duchow, A.S., Jarius, S., Kuhle, J., Benkert, P., Brandt, A.U., Bellmann-Strobl, J., Schmitz-Hübsch, T., Paul, F., Ruprecht, K. and Zimmermann, H.G.
Multiple Sclerosis and Related Disorders 67
: 104100.
November 2022
Fibrin-targeting molecular MRI in inflammatory CNS disorders.
Lohmeier, J., Silva, R.V., Tietze, A., Taupitz, M., Kaneko, T., Prüss, H., Paul, F., Infante-Duarte, C., Hamm, B., Caravan, P. and Makowski, M.R.
European Journal of Nuclear Medicine and Molecular Imaging 49
(11): 3692–3704.
September 2022
Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.
Lorenz, C., Zink, A., Henke, M.T., Staege, S., Mlody, B., Bünning, M., Wanker, E., Diecke, S., Schuelke, M. and Prigione, A.
Stem Cell Research 61
: 102742.
May 2022
Regulation of early cerebellar development.
Lowenstein, E., Cui, K. and Hernandez-Miranda, L.R.
FEBS Journal 290
(11): 2786-2804.
June 2022
Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders.
Lu, A., Zimmermann, H.G., Specovius, S., Motamedi, S., Chien, C., Bereuter, C., Lana-Peixoto, M.A., Fontenelle, M.A., Ashtari, F., Kafieh, R., Dehghani, A., Pourazizi, M., Pandit, L., D'Cunha, A., Kim, H.J., Hyun, J.W., Jung, S.K., Leocani, L., Pisa, M., Radaelli, M., Siritho, S., May, E.F., Tongco, C., De Sèze, J., Senger, T., Palace, J., Roca-Fernández, A., Leite, M.I., Sharma, S.M., Stiebel-Kalish, H., Asgari, N., Soelberg, K.K., Martinez-Lapiscina, E.H., Havla, J., Mao-Draayer, Y., Rimler, Z., Reid, A., Marignier, R., Cobo-Calvo, A., Altintas, A., Tanriverdi, U., Yildirim, R., Aktas, O., Ringelstein, M., Albrecht, P., Tavares, I.M., Bichuetti, D.B., Jacob, A., Huda, S., Soto de Castillo, I., Petzold, A., Green, A.J., Yeaman, M.R., Smith, T.J., Cook, L., Paul, F., Brandt, A.U. and Oertel, F.C.
Journal of Neurology Neurosurgery and Psychiatry 93
(2): 188-195.
February 2022
Renal deletion of LRRC8/VRAC channels induces proximal tubulopathy.
López-Cayuqueo, K.I., Planells-Cases, R., Pietzke, M., Oliveras, A., Kempa, S., Bachmann, S. and Jentsch, T.J.
Journal of the American Society of Nephrology 33
(8): 1528-1545.
August 2022
Imaging and analysis of neuronal mitochondria in murine acute brain slices.
Malla, B., Hauser, A., Niesner, R. and Infante-Duarte, C.
Journal of Neuroscience Methods 372
: 109558.
15 April 2022
Teriflunomide preserves neuronal activity and protects mitochondria in brain slices exposed to oxidative stress.
Malla, B., Liotta, A., Bros, H., Ulshöfer, R., Paul, F., Hauser, A.E., Niesner, R. and Infante-Duarte, C.
International Journal of Molecular Sciences 23
(3): 1538.
28 January 2022
Forebrain development - an intricate balance decides between health and disease.
Mamo, T.M. and Hammes, A.
Neuroforum 28
(4): 233-243.
25 November 2022
Satellite glia of the adult dorsal root ganglia harbor stem cells that yield glia under physiological conditions and neurons in response to injury.
Maniglier, M., Vidal, M., Bachelin, Corinne, Deboux, C., Chazot, J., Garcia-Diaz, B. and Baron-Van Evercooren, A.
Stem Cell Reports 17
(11): 2467-2483.
8 November 2022
In vitro Kinase-to-Phosphosite database (iKiP-DB) predicts kinase activity in phosphoproteomic datasets.
Mari, T., Mösbauer, K., Wyler, E., Landthaler, M., Drosten, C. and Selbach, M.
Journal of Proteome Research 21
(6): 1575-1587.
3 June 2022
AQP4-IgG-seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.
Marignier, R., Pittock, S.J., Paul, F., Kim, H.J., Bennett, J. L., Weinshenker, B.G., Wingerchuk, D.M., Green, A.J., Fujihara, K., Cutter, G., Aktas, O., Hartung, H.P., Drappa, J., Ratchford, J.N., She, D., Smith, M., Rees, W., Cimbora, D., Katz, E. and Cree, B.A.C.
Multiple Sclerosis and Related Disorders 57
: 103356.
January 2022
The Cl(-)-channel TMEM16A is involved in the generation of cochlear Ca(2+) waves and promotes the refinement of auditory brainstem networks in mice.
Maul, A., Huebner, A.K., Strenzke, N., Moser, T., Rübsamen, R., Jovanovic, S. and Hübner, C.A.
eLife 11
: e72251.
24 February 2022
Assessing the relationship of patient reported outcome measures with functional status in dysferlinopathy: a Rasch analysis approach.
Mayhew, A.G., James, M.K., Moore, U., Sutherland, H., Jacobs, M., Feng, J., Lowes, L.P., Alfano, L.N., Muni Lofra, R., Rufibach, L.E., Rose, K., Duong, T., Bello, L., Pedrosa-Hernández, I., Holsten, S., Sakamoto, C., Canal, A., Sánchez-Aguilera Práxedes, N., Thiele, S., Siener, C., Vandevelde, B., DeWolf, B., Maron, E., Gordish-Dressman, H., Hilsden, H., Guglieri, M., Hogrel, J.Y., Blamire, A.M., Carlier, P.G., Spuler, S., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Pestronk, A., Walter, M.C., Paradas, C., Stojkovic, T., Mori-Yoshimura, M., Bravver, E., Díaz-Manera, J., Pegoraro, E., Mendell, J.R. and Straub, V.
Frontiers in Neurology 13
: 828525.
10 March 2022
Physiological functions of intracellular protein degradation.
McShane, E. and Selbach, M.
Annual Review of Cell and Developmental Biology 38
: 241-262.
October 2022
Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis.
Meaton, I., Altokhis, A., Allen, C.M., Clarke, M.A., Sinnecker, T., Meier, D., Enzinger, C., Calabrese, M., De Stefano, N., Pitiot, A., Giorgio, A., Schoonheim, M.M., Paul, F., Pawlak, M.A., Schmidt, R., Granziera, C., Kappos, L., Montalban, X., Rovira, À., Wuerfel, Jens and Evangelou, N.
Multiple Sclerosis Journal 28
(14): 2212-2220.
December 2022
Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T., Lindemann, P., Welle, A., Trouillet, V., Heißler, S., Nazaré, M. and Selbach, M.
ChemMedChem 17
(19): e202200346.
6 October 2022
Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E., Escobar, H., Sunaga-Franze, D.Y., Sauer, S., Diecke, S. and Spuler, S.
Biomedicines 10
(5): 1204.
23 May 2022
Diagnostik der Neuromyelitis-optica-Spektrum-Erkrankung (NMOSD) und der MOG-Antikörper-assoziierten Erkrankung (MOGAD) [Diagnosis of neuromyelitis optica spectrum disorder (NMOSD) and MOG Antibody-associated disease (MOGAD)].
Mewes, D., Kuchling, J., Schindler, P., Khalil, A.A.A., Jarius, S., Paul, F. and Chien, C.
Klinische Monatsblatter fur Augenheilkunde 239
(11): 1315-1324.
November 2022
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt, L., Braun, J., Fauchere, F., Vanshylla, K., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Jürchott, K., Mangold, M., Maraj, A., Braginets, A., Böttcher, C., Nitsche, A., de la Rosa, K., Ratswohl, C., Sawitzki, B., Holenya, P., Reimer, U., Sander, L.E., Klein, F., Paul, F., Bellmann-Strobl, J., Thiel, A. and Giesecke-Thiel, C.
Journal of Neurology Neurosurgery and Psychiatry 93
(9): 960-971.
September 2022
Prefrontal-amygdala emotion regulation and depression in multiple sclerosis.
Meyer-Arndt, L., Kuchling, J., Brasanac, J., Hermann, A., Asseyer, S., Bellmann-Strobl, J., Paul, F., Gold, S.M. and Weygandt, M.
Brain Communications 4
(3): fcac152.
13 June 2022
Cutting edge: Serum but not mucosal antibody responses are associated with pre-existing SARS-CoV-2 spike cross-reactive CD4(+) T cells following BNT162b2 vaccination in the elderly.
Meyer-Arndt, L., Schwarz, T., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Gürcan, K., Uyar-Aydin, Z., Müller, M.A., Drosten, C., Paul, F., Sander, L.E., Demuth, I., Lauster, R., Giesecke-Thiel, C., Braun, J., Corman, V.M. and Thiel, A.
Journal of Immunology 208
(5): 1001-1008.
1 March 2022
Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C., Lisowski, P., Lickfett, S., Mlody, B., Bünning, M., Genehr, C., Ulrich, C., Wanker, E.E., Diecke, S., Priller, J. and Prigione, A.
Stem Cell Research 65
: 102976.
December 2022
Bin-based visualization of cytokine-co-expression patterns of IL-10-producing CD4 T cell subsets.
Mohr, E., Hinnenthal, T., Gryzik, S., Hoang, Y., Lischke, T., Retzlaff, J., Mekonnen, A., Paul, F., Valleriani, A., Radbruch, A., Vera, J. and Baumgrass, R.
European Journal of Immunology 52
(10): 1684-1687.
October 2022
In vitro and in vivo anti‐epileptic efficacy of eslicarbazepine acetate in a mouse model of KCNQ2‐related self‐limited epilepsy.
Monni, L., Kraus, L., Dipper‐Wawra, M., Soares‐da‐Silva, P., Maier, N., Schmitz, D., Holtkamp, M. and Fidzinski, P.
British Journal of Pharmacology 179
(1): 84-102.
January 2022
Cardiac and pulmonary findings in dysferlinopathy: a 3-year, longitudinal study.
Moore, U., Fernandez-Torron, R., Jacobs, M., Gordish, H., Diaz-Manera, J., James, M.K., Mayhew, A.G., Harris, E., Guglieri, M., Rufibach, L.E., Feng, J., Blamire, A.M., Carlier, P.G., Spuler, S., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Pestronk, A., Walter, M.C., Paradas, C., Stojkovic, T., Mori-Yoshimura, M., Bravver, E., Pegoraro, E., Lowes, L.P., Mendell, J.R., Bushby, K., Bourke, J. and Straub, V.
Muscle & Nerve 65
(5): 531-540.
May 2022
Mechanical properties of murine hippocampal subregions investigated by atomic force microscopy and in vivo magnetic resonance elastography.
Morr, A.S., Nowicki, M., Bertalan, G., Silva, R.V., Infante Duarte, C., Koch, S.P., Boehm-Sturm, P., Krügel, U., Braun, J., Steiner, B., Käs, J.A., Fuhs, T. and Sack, I.
Scientific Reports 12
(1): 16723.
6 October 2022
Prior optic neuritis detection on peripapillary ring scans using deep learning.
Motamedi, S., Yadav, S.K., Kenney, R.C., Lin, T.Y., Kauer-Bonin, J., Zimmermann, H.G., Galetta, S.L., Balcer, L.J., Paul, F. and Brandt, A.U.
Annals of Clinical and Translational Neurology 9
(11): 1682-1691.
November 2022
Protocol and reference values for minimal detectable change of MyotonPRO and ultrasound imaging measurements of muscle and subcutaneous tissue.
Muckelt, P.E., Warner, M.B., Cheliotis-James, T., Muckelt, R., Hastermann, M., Schoenrock, B., Martin, D., MacGregor, R., Blottner, D. and Stokes, M.
Scientific Reports 12
(1): 13654.
11 August 2022
Choroid plexus volume in multiple sclerosis vs neuromyelitis optica spectrum disorder: a retrospective, cross-sectional analysis.
Müller, J., Sinnecker, T., Wendebourg, M.J., Schläger, R., Kuhle, J., Schädelin, S., Benkert, P., Derfuss, T., Cattin, P., Jud, C., Spiess, F., Amann, M., Lincke, T., Barakovic, M., Cagol, A., Tsagkas, C., Parmar, K., Pröbstel, A.K., Reimann, S., Asseyer, S., Duchow, A., Brandt, A., Ruprecht, K., Hadjikhani, N., Fukumoto, S., Watanabe, M., Masaki, K., Matsushita, T., Isobe, N., Kira, J.I., Kappos, L., Würfel, J., Granziera, C., Paul, F. and Yaldizli, Ö.
Neurology Neuroimmunology & Neuroinflammation 9
(3): e1147.
May 2022
The molecular mechanism and physiological role of silent nociceptor activation.
Nees, T.A., Wang, N., Adamek, P., Verkest, C., Schaefer, I., Virnich, J., Balkaya, S., Prato, V., Morelli, C., Zeitzschel, N., Begay, V., Lee, Y.J., Lewin, G.R., Heppenstall, P.A., Taberner, F.J. and Lechner, S.G.
bioRxiv
: 2022.04.07.486730.
19 October 2022
Best practice standards for circular RNA research.
Nielsen, A.F., Bindereif, A., Bozzoni, I., Hanan, M., Hansen, T.B., Irimia, M., Kadener, S., Kristensen, L.S., Legnini, I., Morlando, M., Jarlstad Olesen, M.T., Pasterkamp, R.J., Preibisch, S., Rajewsky, N., Suenkel, C. and Kjems, J.
Nature Methods 19
(10): 1208-1220.
October 2022
Upregulated complement receptors correlate with Fc gamma receptor 3A-positive natural killer and natural killer-T cells in neuromyelitis optica spectrum disorder.
Nishiyama, S., Wright, A.E., Lotan, I., Mikami, T., Paul, F., Aoki, M. and Levy, M.
Journal of Neuroinflammation 19
(1): 296.
12 December 2022
Brain-wide interactions during hippocampal sharp wave ripples.
Nitzan, N., Swanson, R., Schmitz, D. and Buzsáki, G.
Proceedings of the National Academy of Sciences of the United States of America 119
(20): e2200931119.
17 May 2022
Longitudinal retinal changes in MOGAD.
Oertel, F.C., Sotirchos, E.S., Zimmermann, H.G., Motamedi, S., Specovius, S., Asseyer, E.S., Chien, C., Cook, L., Vasileiou, E., Filippatou, A., Calabresi, P.A., Saidha, S., Pandit, L., D'Cunha, A., Outteryck, O., Zéphir, H., Pittock, S., Flanagan, E.P., Bhatti, M.T., Rommer, P.S., Bsteh, G., Zrzavy, T., Kuempfel, T., Aktas, O., Ringelstein, M., Albrecht, P., Ayzenberg, I., Pakeerathan, T., Knier, B., Aly, L., Asgari, N., Soelberg, K., Marignier, R., Tilikete, C.F., Calvo, A.C., Villoslada, P., Sanchez-Dalmau, B., Martinez-Lapiscina, E.H., Llufriu, S., Green, A.J., Yeaman, M.R., Smith, T.J., Brandt, A.U., Chen, J., Paul, F. and Havla, J.
Annals of Neurology 92
(3): 476-485.
September 2022
Lack of evidence for participation of TMEM150C in sensory mechanotransduction.
Ojeda-Alonso, J., Bégay, V., Garcia-Contreras, J.A., Campos-Pérez, A.F., Purfürst, B. and Lewin, G.R.
Journal of General Physiology 154
(12): e202213098.
5 December 2022
Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla, T., Gollasch, B., Kuich, P.H.J.L., Klug, L., Rahn, G., Busjahn, A., Spuler, S., Boschmann, M., Kirwan, J.A., Luft, F.C. and Kempa, S.
Frontiers in Molecular Biosciences 9
: 1042231.
21 December 2022
Microglia states and nomenclature: A field at its crossroads.
Paolicelli, R.C., Sierra, A., Stevens, B., Tremblay, M.E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., Bennett, F., Bessis, A., Biber, K., Bilbo, S., Blurton-Jones, M., Boddeke, E., Brites, D., Brône, B., Brown, G.C., Butovsky, O., Carson, M.J., Castellano, B., Colonna, M., Cowley, S.A., Cunningham, C., Davalos, D., De Jager, P.L., de Strooper, B., Denes, A., Eggen, B.J.L., Eyo, U., Galea, E., Garel, S., Ginhoux, F., Glass, C.K., Gokce, O., Gomez-Nicola, D., González, B., Gordon, S., Graeber, M.B., Greenhalgh, A.D., Gressens, P., Greter, M., Gutmann, D.H., Haass, C., Heneka, M.T., Heppner, F.L., Hong, S., Hume, D.A., Jung, S., Kettenmann, H., Kipnis, J., Koyama, R., Lemke, G., Lynch, M., Majewska, A., Malcangio, M., Malm, T., Mancuso, R., Masuda, T., Matteoli, M., McColl, B.W., Miron, V.E., Molofsky, A.V., Monje, M., Mracsko, E., Nadjar, A., Neher, J.J., Neniskyte, U., Neumann, H., Noda, M., Peng, B., Peri, F., Perry, V.H., Popovich, P.G., Pridans, C., Priller, J., Prinz, M., Ragozzino, D., Ransohoff, R.M., Salter, M.W., Schaefer, A., Schafer, D.P., Schwartz, M., Simons, M., Smith, C.J., Streit, W.J., Tay, T.L., Tsai, L.H., Verkhratsky, A., von Bernhardi, R., Wake, H., Wittamer, V., Wolf, S.A., Wu, L.J. and Wyss-Coray, T.
Neuron 110
(21): 3458-3483.
2 November 2022
Arzneimittelversorgung bei Multipler Sklerose.
Paul, F. and Berthele, A.
In:
Arzneimittel-Kompass 2022: Qualität der Arzneimittelversorgung.
Springer, Berlin, Heidelberg, 139-159.
ISBN 978-3-662-66040-9
2022
Diagnosis and classification of optic neuritis.
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Long-term imaging reveals behavioral plasticity during C. elegans dauer exit.
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P2X7 receptor antagonist reduces fibrosis and inflammation in a mouse model of alpha-sarcoglycan muscular dystrophy.
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A novel gene controls a new structure: piggyBac transposable element-derived 1, unique to mammals, controls mammal-specific neuronal paraspeckles.
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SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
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18 February 2022
Interleukin-6 receptor blockade in treatment-refractory MOG-IgG-associated disease and neuromyelitis optica spectrum disorders.
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Brain disconnectome mapping derived from white matter lesions and serum neurofilament light levels in multiple sclerosis: a longitudinal multicenter study.
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Hypoxia differentially affects healthy men and women during a daytime nap with a dose-response relationship: a randomized, cross-over pilot study.
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Functional connectivity dynamics reflect disability and multi-domain clinical impairment in patients with relapsing-remitting multiple sclerosis.
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Estimation and testing of Wilcoxon–Mann–Whitney effects in factorial clustered data designs.
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Panoptic segmentation with highly imbalanced semantic labels.
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How shift equivariance impacts metric learning for instance segmentation.
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Proposal for post hoc quality control in instrumented motion analysis using markerless motion capture: development and usability study.
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The synaptic scaffold protein MPP2 interacts with GABA(A) receptors at the periphery of the postsynaptic density of glutamatergic synapses.
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Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
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Gating choreography and mechanism of the human proton-activated chloride channel ASOR.
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Network meta-analysis of food and drug administration-approved treatment options for adults with aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorder.
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Alterations of NK cell phenotype during pregnancy in multiple sclerosis.
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The host peritoneal cavity harbors prominent memory Th2 and early recall responses to an intestinal nematode.
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Novel targets, treatments, and advanced models for intracerebral haemorrhage.
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TSLP as druggable target - a silver-lining for atopic diseases?
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A role for STOML3 in olfactory sensory transduction.
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AQP4-IgG autoimmunity in Japan and Germany: differences in clinical profiles and prognosis in seropositive neuromyelitis optica spectrum disorders.
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1 April 2021
APOSTEL 2.0 recommendations for reporting quantitative optical coherence tomography studies.
Aytulun, A., Cruz-Herranz, A., Aktas, O., Balcer, L.J., Balk, L., Barboni, P., Blanco, A.A., Calabresi, P.A., Costello, F., Sanchez-Dalmau, B., DeBuc, D.C., Feltgen, N., Finger, R.P., Frederiksen, J.L., Frohman, E., Frohman, T., Garway-Heath, D., Gabilondo, I., Graves, J.S., Green, A.J., Hartung, H.P., Havla, J., Holz, F.G., Imitola, J., Kenney, R., Klistorner, A., Knier, B., Korn, T., Kolbe, S., Krämer, J., Lagrèze, W.A., Leocani, L., Maier, O., Martínez-Lapiscina, E.H., Meuth, S., Outteryck, O., Paul, F., Petzold, A., Pihl-Jensen, G., Preiningerova, J.L., Rebolleda, G., Ringelstein, M., Saidha, S., Schippling, S., Schuman, J.S., Sergott, R.C., Toosy, A., Villoslada, P., Wolf, S., Yeh, E.A., Yu-Wai-Man, P., Zimmermann, H.G., Brandt, A.U. and Albrecht, P.
Neurology 97
(2): 68-79.
13 July 2021
Pain, depression, and quality of life in neuromyelitis optica spectrum disorder: a cross-sectional study of 166 AQP4 antibody-seropositive patients.
Ayzenberg, I., Richter, D., Henke, E., Asseyer, S., Paul, F., Trebst, C., Hümmert, M.W., Havla, J., Kümpfel, T., Ringelstein, M., Aktas, O., Wildemann, B., Jarius, S., Häußler, V., Stellmann, J.P., Senel, M., Klotz, L., Pellkofer, H.L., Weber, M.S., Pawlitzki, M., Rommer, P.S., Berthele, A., Wernecke, K.D., Hellwig, K., Gold, R. and Kleiter, I.
Neurology Neuroimmunology & Neuroinflammation 8
(3): e985.
May 2021
Hearing and vocalizations in the naked mole-rat.
Barker, A.J., Koch, U., Lewin, G.R. and Pyott, S.J.
Advances in Experimental Medicine and Biology 1319
(1319): 157-195.
24 August 2021
Cultural transmission of vocal dialect in the naked mole-rat.
Barker, A.J., Veviurko, G., Bennett, N.C., Hart, D.W., Mograby, L. and Lewin, G.R.
Science 371
(6528): 503-507.
29 January 2021
Clinical and neuroimaging findings in MOGAD - MRI and OCT.
Bartels, F., Lu, A., Oertel, F.C., Finke, C., Paul, F. and Chien, C.
Clinical and Experimental Immunology 206
(3): 266-281.
December 2021
Diurnal variations in the expression of core-clock genes correlate with resting muscle properties and predict fluctuations in exercise performance across the day.
Basti, A., Yalçin, M., Herms, D., Hesse, J., Aboumanify, O., Li, Y., Aretz, Z., Garmshausen, J., El-Athman, R., Hastermann, M., Blottner, D. and Relógio, A.
BMJ Open Sport & Exercise Medicine 7
(1): e000876.
10 February 2021
Epigallocatechin gallate in relapsing-remitting multiple sclerosis: a randomized, placebo-controlled trial.
Bellmann-Strobl, J., Paul, F., Wuerfel, J., Dörr, J., Infante-Duarte, C., Heidrich, E., Körtgen, B., Brandt, A., Pfüller, C., Radbruch, H., Rust, R., Siffrin, V., Aktas, O., Heesen, C., Faiss, J., Hoffmann, F., Lorenz, M., Zimmermann, B., Groppa, S., Wernecke, K.D. and Zipp, F.
Neurology Neuroimmunology & Neuroinflammation 8
(3): e981.
May 2021
Deep tissue scattering compensation with three-photon F-SHARP.
Berlage, C., Tantirigama, M.L.S., Babot, M., Di Battista, D., Whitmire, C., Papadopoulos, I.N., Poulet, J.F.A., Larkum, M. and Judkewitz, B.
Optica 8
(12): 1613-1619.
20 December 2021
Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis.
Bernardo-Faura, M., Rinas, M., Wirbel, J., Pertsovskaya, I., Pliaka, V., Messinis, D.E., Vila, G., Sakellaropoulos, T., Faigle, W., Stridh, P., Behrens, J.R., Olsson, T., Martin, R., Paul, F., Alexopoulos, L.G., Villoslada, P. and Saez-Rodriguez, J.
Genome Medicine 13
(1): 117.
16 July 2021
Time to diagnosis in multiple sclerosis: epidemiological data from the German Multiple Sclerosis Registry.
Blaschke, S.J., Ellenberger, D., Flachenecker, P., Hellwig, K., Paul, F., Pöhlau, D., Kleinschnitz, C., Rommer, P.S., Rueger, M.A., Zettl, U.K., Stahmann, A. and Warnke, C.
Multiple Sclerosis 28
(6): 865-871.
May 2021
Progressive myocardial injury in myotonic dystrophy type II and facioscapulohumeral muscular dystrophy 1: a cardiovascular magnetic resonance follow-up study.
Blaszczyk, E., Lim, C., Kellman, P., Schmacht, L., Gröschel, J., Spuler, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 23
(1): 130.
8 November 2021
Myogenic cell transplantation in genetic and acquired diseases of skeletal muscle.
Boyer, O., Butler-Browne, G., Chinoy, H., Cossu, G., Galli, F., Lilleker, J.B., Magli, A., Mouly, V., Perlingeiro, R.R., Previtali, S.C., Sampaolesi, M., Smeets, H., Schoewel-Wolf, V., Spuler, S., Torrente, Y. and Van Tienen, F.
Frontiers in Genetics 12
: 702547.
August 2021
Association of a marker of N-acetylglucosamine with progressive multiple sclerosis and neurodegeneration.
Brandt, A.U., Sy, M., Bellmann-Strobl, J., Newton, B.L., Pawling, J., Zimmermann, H.G., Yu, Z., Chien, C., Dörr, J., Wuerfel, J.T., Dennis, J.W., Paul, F. and Demetriou, M.
JAMA Neurology 78
(7): 842-852.
July 2021
Mitochondria in neurogenesis: implications for mitochondrial diseases.
Brunetti, D., Dykstra, W., Le, S., Zink, A. and Prigione, A.
Stem Cells 39
(10): 1289-1297.
October 2021
The delivery challenge of genome editing in human epithelia.
Calderón, M. and Hedtrich, S.
Advanced Healthcare Materials 10
(19): e2100847.
October 2021
Functional characterization of ovine dorsal root ganglion neurons reveal peripheral sensitization after osteochondral defect.
Chakrabarti, S., Ai, M., Wong, K., Newell, K., Henson, F.M.D. and Smith, E.S.J.
eNeuro 8
(5): ENEURO.0237-21.2021.
September 2021
Design and testing of efficient mucus-penetrating nanogels-pitfalls of preclinical testing and lessons learned.
Charbaji, R., Kar, M., Theune, L.E., Bergueiro, J., Eichhorst, A., Navarro, L., Graff, P., Stumpff, F., Calderón, M. and Hedtrich, S.
Small 17
(23): e2007963.
10 June 2021
FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development.
Chua, J.Y., Ng, S.J., Yagensky, O., Wanker, E.E. and Chua, J.J.E.
eNeuro 8
(2): ENEURO.0193-20.2021.
26 March 2021
Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G., Bay, O., Zinno, J., Gutwein, M., Gan, H.H., Mayya, V.K., Chung, G., Chen, J.X., Fahs, H., Guan, Y., Duchaine, T.F., Selbach, M., Piano, F. and Gunsalus, K.C.
eLife 10
: e60833.
3 August 2021
Assessing attacks and treatment response rates among adult patients with NMOSD and MOGAD: data from a nationwide registry in Argentina.
Contentti, E.C., Lopez, P.A., Pettinicchi, J.P., Criniti, J., Pappolla, A., Miguez, J., Patrucco, L., Carnero Contentti, E., Liwacki, S., Tkachuk, V., Balbuena, M.E., Vrech, C., Deri, N., Correale, J., Marrodan, M., Ysrraelit, M.C., Leguizamon, F., Luetic, G., Menichini, M.L., Tavolini, D., Mainella, C., Zanga, G., Burgos, M., Hryb, J., Barboza, A., Lazaro, L., Alonso, R., Liguori, N.F., Nadur, D., Chercoff, A., Alonso Serena, M., Caride, A., Paul, F. and Rojas, J.I.
Multiple Sclerosis Journal Experimental Translational and Clinical 7
(3): 20552173211032334.
1 July 2021
Longitudinal analysis of T1w/T2w ratio in patients with multiple sclerosis from first clinical presentation.
Cooper, G., Chien, C., Zimmermann, H., Bellmann-Strobl, J., Ruprecht, K., Kuchling, J., Asseyer, S., Brandt, A.U., Scheel, M., Finke, C. and Paul, F.
Multiple Sclerosis Journal 27
(14): 2180-2190.
December 2021
Retinal INL thickness in multiple sclerosis: a mere marker of neurodegeneration?
Cordano, C., Yiu, H.H, Oertel, F.C., Gelfand, J.M., Hauser, S.L., Cree, B.A.C. and Green, Ari J.
Annals of Neurology 89
(1): 192-193.
January 2021
From forensics to clinical research: expanding the variant calling pipeline for the precision ID mtDNA whole genome panel.
Cortes-Figueiredo, F., Carvalho, F.S., Fonseca, A.C., Paul, F., Ferro, J.M., Schönherr, S., Weissensteiner, H. and Morais, V.A.
International Journal of Molecular Sciences 22
(21): 12031.
6 November 2021
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).
Cossarizza, A., Chang, H.D., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., Bacher, P., Bari, S., Barnaba, V., Barros-Martins, J., Baumjohann, D., Beccaria, C.G., Bernardo, D., Boardman, D.A., Borger, J., Böttcher, C., Brockmann, L., Burns, M., Busch, D.H., Cameron, G., Cammarata, I., Cassotta, A., Chang, Y., Chirdo, F.G., Christakou, E., Čičin-Šain, L., Cook, L., Corbett, A.J., Cornelis, R., Cosmi, L., Davey, M.S., De Biasi, S., De Simone, G., Del Zotto, G., Delacher, M., Di Rosa, F., Santo, J.D., Diefenbach, A., Dong, J., Dörner, T., Dress, R.J., Dutertre, C.A., Eckle, S.B.G., Eede, P., Evrard, M., Falk, C.S., Feuerer, M., Fillatreau, S., Fiz-Lopez, A., Follo, M., Foulds, G.A., Fröbel, J., Gagliani, N., Galletti, G., Gangaev, A., Garbi, N., Garrote, J.A., Geginat, J., Gherardin, N.A., Gibellini, L., Ginhoux, F., Godfrey, D.I., Gruarin, P., Haftmann, C., Hansmann, L., Harpur, C.M., Hayday, A.C., Heine, G., Hernández, D.C., Herrmann, M., Hoelsken, O., Huang, Q., Huber, S., Huber, J.E., Huehn, J., Hundemer, M., Hwang, W.Y.K., Iannacone, M., Ivison, S.M., Jäck, H.M., Jani, P.K., Keller, B., Kessler, N., Ketelaars, S., Knop, L., Knopf, J., Koay, H.F., Kobow, K., Kriegsmann, K., Kristyanto, H., Krueger, A., Kuehne, J.F., Kunze-Schumacher, H., Kvistborg, P., Kwok, I., Latorre, D., Lenz, D., Levings, M.K., Lino, A.C., Liotta, F., Long, H.M., Lugli, E., MacDonald, K.N., Maggi, L., Maini, M.K., Mair, F., Manta, C., Manz, R.S., Mashreghi, M.F., Mazzoni, A., McCluskey, J., Mei, H.E., Melchers, F., Melzer, S., Mielenz, D., Monin, L., Moretta, L., Multhoff, G., Muñoz, L.E., Muñoz-Ruiz, M., Muscate, F., Natalini, A., Neumann, K., Ng, L.G., Niedobitek, A., Niemz, J., Almeida, L.N., Notarbartolo, S., Ostendorf, L., Pallett, L.J., Patel, A.A., Percin, G.I., Peruzzi, G., Pinti, M., Pockley, A.G., Pracht, K., Prinz, I., Pujol-Autonell, I., Pulvirenti, N., Quatrini, L., Quinn, K.M., Radbruch, H., Rhys, H., Rodrigo, M.B., Romagnani, C., Saggau, C., Sakaguchi, S., Sallusto, F., Sanderink, L., Sandrock, I., Schauer, C., Scheffold, A., Scherer, H.U., Schiemann, M., Schildberg, F.A., Schober, K., Schoen, J., Schuh, W., Schüler, T., Schulz, A.R., Schulz, S., Schulze, J., Simonetti, S., Singh, J., Sitnik, K.M., Stark, R., Starossom, S., Stehle, C., Szelinski, F., Tan, L., Tarnok, A., Tornack, J., Tree, T.I.M., van Beek, J.J.P., van de Veen, W., van Gisbergen, K., Vasco, C., Verheyden, N.A., von Borstel, A., Ward-Hartstonge, K.A., Warnatz, K., Waskow, C., Wiedemann, A., Wilharm, A., Wing, J., Wirz, O., Wittner, J., Yang, J.H.M. and Yang, J.
European Journal of Immunology 51
(12): 2708-3145.
December 2021
Deletion of muscarinic acetylcholine receptor 3 in microglia impacts brain ischemic injury.
Costa, A., Haage, V., Yang, S., Wegner, S., Ersoy, B., Ugursu, B., Rex, A., Kronenberg, G., Gertz, K., Endres, M., Wolf, S.A. and Kettenmann, H.
Brain Behavior and Immunity 91
: 89-104.
January 2021
Sensitivity analysis of the primary endpoint from the N-MOmentum study of inebilizumab in NMOSD.
Cree, B.A.C., Bennett, J.L., Kim, H.J., Weinshenker, B.G., Pittock, S.J., Wingerchuk, D., Fujihara, K., Paul, F., Cutter, G.R., Marignier, R., Green, A.J., Aktas, O., Hartung, H.P., Williams, I.M., Drappa, J., She, D., Cimbora, D., Rees, W., Ratchford, J.N. and Katz, E.
Multiple Sclerosis Journal 27
(13): 2052-2061.
1 November 2021
Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis.
Cruz-Herranz, A., Oertel, F.C., Kim, K., Cantó, E., Timmons, G., Sin, J.H., Devereux, M., Baker, N., Michel, B., Schubert, R.D., Rani, L., Cordano, C., Baranzini, S.E. and Green, A.J.
JCI Insight 6
(11): e149228.
8 June 2021
N2 year in review.
Dalmau, J., Dalakas, M.C., Kolson, D.L., Paul, F. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 8
(1): e925.
January 2021
A medullary centre for lapping in mice.
Dempsey, B., Sungeelee, S., Bokiniec, P., Chettouh, Z., Diem, S., Autran, S., Harrell, E.R., Poulet, J.F.A., Birchmeier, C., Carey, H., Genovesio, A., McMullan, S., Goridis, C., Fortin, G. and Brunet, J.F.
Nature Communications 12
: 6307.
2 November 2021
An executive center for the intake of liquids.
Dempsey, B., Sungeelee, S., Bokiniec, P., Chettouh, Z., Diem, S., Autran, S., Harrell, E.R., Poulet, J.F.A., Birchmeier, C., Carrey, H., Genovesio, A., McMullan, S., Goridis, C., Fortin, G. and Brunet, J.F.
bioRxiv
: 2021.07.02.450862.
4 July 2021
Characterization of an ester-based core-multishell (CMS) nanocarrier for the topical application at the oral mucosa.
Dommisch, H., Stolte, K.N., Jager, J., Vogel, K., Müller, R., Hedtrich, S., Unbehauen, M., Haag, R. and Danker, K.
Clinical Oral Investigations 25
(10): 5795-5805.
October 2021
Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M., Klinger, B., Mari, T., Toedling, J., Blanc, E., Messerschmidt, C., Nadler-Holly, M., Ziehm, M., Sieber, A., Hertwig, F., Beule, D., Eggert, A., Schulte, J.H., Selbach, M. and Blüthgen, N.
PLoS Computational Biology 17
(11): e1009515.
4 November 2021
Satralizumab in the treatment of neuromyelitis optica spectrum disorder.
Duchow, A. and Bellmann-Strobl, J.
Neurodegenerative Disease Management 11
(1): 49-59.
February 2021
Sensory neurons: the formation of T-shaped branches is dependent on a cGMP-dependent signaling cascade.
Dumoulin, A., Schmidt, H. and Rathjen, F.G.
Neuroscientist 27
(1): 47-57.
1 February 2021
Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders.
Duncan, A.R., Polovitskaya, M.M., Gaitán-Peñas, H., Bertelli, S., VanNoy, G.E., Grant, P.E., O'Donnell-Luria, A., Valivullah, Z., Lovgren, A.K., England, E.M., Agolini, E., Madden, J.A., Schmitz-Abe, K., Kritzer, A., Hawley, P., Novelli, A., Alfieri, P., Colafati, G.S., Wieczorek, D., Platzer, K., Luppe, J., Koch-Hogrebe, M., Abou Jamra, R., Neira-Fresneda, J., Lehman, A., Boerkoel, C.F., Seath, K., Clarke, L., van Ierland, Y., Argilli, E., Sherr, E.H., Maiorana, A., Diel, T., Hempel, M., Bierhals, T., Estévez, R., Jentsch, T.J., Pusch, M. and Agrawal, P.B.
American Journal of Human Genetics 108
(8): 1450-1465.
5 August 2021
Patch individual filter layers in CNNs to harness the spatial homogeneity of neuroimaging data.
Eitel, F., Albrecht, J.P., Weygandt, M., Paul, F. and Ritter, K.
Scientific Reports 11
(1): 24447.
27 December 2021
Reactive astrocyte nomenclature, definitions, and future directions.
Escartin, C., Galea, E., Lakatos, A., O'Callaghan, J.P., Petzold, G.C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., Allen, N.J., Araque, A., Barbeito, L., Barzilai, A., Bergles, D.E., Bonvento, G., Butt, A.M., Chen, W.T., Cohen-Salmon, M., Cunningham, C., Deneen, B., De Strooper, B., Díaz-Castro, B., Farina, C., Freeman, M., Gallo, V., Goldman, J.E., Goldman, S.A., Götz, M., Gutiérrez, A., Haydon, P.G., Heiland, D.H., Hol, E.M., Holt, M.G., Iino, M., Kastanenka, K.V., Kettenmann, H., Khakh, B.S., Koizumi, S., Lee, C.J., Liddelow, S.A., MacVicar, B.A., Magistretti, P., Messing, A., Mishra, A., Molofsky, A.V., Murai, K.K., Norris, C.M., Okada, S., Oliet, S.H.R., Oliveira, J.F., Panatier, A., Parpura, V., Pekna, M., Pekny, M., Pellerin, L., Perea, G., Pérez-Nievas, B.G., Pfrieger, F.W., Poskanzer, K.E., Quintana, F.J., Ransohoff, R.M., Riquelme-Perez, M., Robel, S., Rose, C.R., Rothstein, J.D., Rouach, N., Rowitch, D.H., Semyanov, A., Sirko, S., Sontheimer, H., Swanson, R.A., Vitorica, J., Wanner, I.B., Wood, L.B., Wu, J., Zheng, B., Zimmer, E.R., Zorec, R., Sofroniew, M.V. and Verkhratsky, A.
Nature Neuroscience 24
(3): 312-325.
March 2021
Base editing repairs an SGCA mutation in human primary muscle stem cells.
Escobar, H., Krause, A., Keiper, S., Kieshauer, J., Müthel, S., García de Paredes, M., Metzler, E., Kühn, R., Heyd, F. and Spuler, S.
JCI Insight 6
(10): e145994.
24 May 2021
Humane neuromuskuläre Organoide - Anwendung und Perspektive [Human neuromuscular organoids - Application and perspective].
Faustino Martins, J.M., Nguyen, L.V.N. and Gouti, M.
BIOspektrum 27
(2): 135-138.
March 2021
Characteristics of secondary progressive multiple sclerosis: disease activity and provision of care in Germany - a registry-based/multicentric cohort study.
Frahm, N., Ellenberger, D., Fneish, F., Christoph, K., Warnke, C., Zettl, U.K., Paul, F., Rauser, B., Stahmann, A., Vogelmann, V. and Flachenecker, P.
Multiple Sclerosis and Related Disorders 56
: 103281.
November 2021
Overcoming barriers to the adoption of locating technologies in dementia care: a multi-stakeholder focus group study.
Freiesleben, S.D., Megges, H., Herrmann, C., Wessel, L. and Peters, O.
BMC Geriatrics 21
(1): 378.
21 June 2021
Challenges in cell transplantation for muscular dystrophy.
Galli, F., Mouly, V., Butler-Browne, G. and Cossu, G.
Experimental Cell Research 409
(1): 112908.
1 December 2021
Reduced mitochondrial respiration in T cells of patients with major depressive disorder.
Gamradt, S., Hasselmann, H., Taenzer, A., Brasanac, J., Stiglbauer, V., Sattler, A., Sajitz-Hermstein, M., Kierszniowska, S., Ramien, C., Nowacki, J., Mascarell-Maricic, L., Wingenfeld, K., Piber, D., Ströhle, A., Kotsch, K., Paul, F., Otte, C. and Gold, S.M.
iScience 24
(11): 103312.
19 November 2021
Place fields of single spikes in hippocampus involve Kcnq3 channel-dependent entrainment of complex spike bursts.
Gao, X., Bender, F., Soh, H., Chen, C., Altafi, M., Schütze, S., Heidenreich, M., Gorbati, M., Corbu, M.A., Carus-Cadavieco, M., Korotkova, T., Tzingounis, A.V., Jentsch, T.J. and Ponomarenko, A.
Nature Communications 12
(1): 4801.
10 August 2021
Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq.
Glaser, L.V., Steiger, M., Fuchs, A., van Bömmel, A., Einfeldt, E., Chung, H.R., Vingron, M. and Meijsing, S.H.
Nucleic Acids Research 49
(21): 12178-12195.
2 December 2021
Caution, "normal" BMI: health risks associated with potentially masked individual underweight - EPMA position paper 2021.
Golubnitschaja, O., Liskova, A., Koklesova, L., Samec, M., Biringer, K., Büsselberg, D., Podbielska, H., Kunin, A.A., Evsevyeva, M.E., Shapira, N., Paul, F., Erb, C., Dietrich, D.E., Felbel, D., Karabatsiakis, A., Bubnov, R., Polivka, J., Polivka, J.J., Birkenbihl, C., Fröhlich, H., Hofmann-Apitius, M. and Kubatka, P.
EPMA Journal 12
(3): 243-264.
September 2021
Development of SARA(home), a new video-based tool for the assessment of ataxia at home.
Grobe-Einsler, M., Taheri Amin, A., Faber, J., Schaprian, T., Jacobi, H., Schmitz-Hübsch, T., Diallo, A., Tezenas du Montcel, S. and Klockgether, T.
Movement Disorders 36
(5): 1242-1246.
May 2021
Neurochemical differences in spinocerebellar ataxia type 14 and 1.
Grosch, A.S., Rinnenthal, J.L., Rönnefarth, M., Lux, S., Scheel, M., Endres, M., Brandt, A.U., Paul, F., Schmitz-Hübsch, T., Minnerop, M. and Doss, S.
Cerebellum 20
(2): 169-178.
April 2021
Parvalbumin interneurons are differentially connected to principal cells in inhibitory feedback microcircuits along the dorsoventral axis of the medial entorhinal cortex.
Grosser, S., Barreda, F.J., Beed, P., Schmitz, D., Booker, S.A. and Vida, I.
eNeuro 8
(1): ENEURO.0354-20.2020.
2 February 2021
Cellular basis of ClC-2 Cl(-) channel-related brain and testis pathologies.
Göppner, C., Soria, A.H., Hoegg-Beiler, M.B. and Jentsch, T.J.
Journal of Biological Chemistry 296
: 100074.
4 January 2021
The need for sustainable leadership in academia : a survey of academics in Germany shows a lack of and a great demand for training in leadership skills.
Haage, V., Voss, L., Nguyen, D. and Eggert, F.
EMBO Reports 22
(12): e53592.
6 December 2021
Timed global reorganization of protein synthesis during neocortex neurogenesis at codon resolution.
Harnett, D., Ambrozkiewicz, M.C., Zinnall, U., Borisova, E., Rusanova, A., Dannenberg, R., Imami, K., Münster-Wandowski, A., Fauler, B., Mielke, T., Selbach, M., Landthaler, M., Spahn, C.M.T., Tarabykin, V., Ohler, U. and Kraushar, M.L.
bioRxiv
: 2021.06.23.449626.
24 June 2021
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A., Sieverling, L., Nadler-Holly, M., Ziehm, M., Toprak, U.H., Herrmann, C., Ishaque, N., Okonechnikov, K., Gartlgruber, M., Park, Y.G., Wecht, E.M., Savelyeva, L., Henrich, K.O., Rosswog, C., Fischer, M., Hero, B., Jones, D.T.W., Pfaff, E., Witt, O., Pfister, S.M., Volckmann, Ri., Koster, J., Kiesel, K., Rippe, K., Taschner-Mandl, S., Ambros, P., Brors, B., Selbach, M., Feuerbach, L. and Westermann, F.
Nature Communications 12
(1): 1269.
24 February 2021
Delayed access to conscious processing in multiple sclerosis: reduced cortical activation and impaired structural connectivity.
Has Silemek, A.C., Ranjeva, J.P., Audoin, B., Heesen, C., Gold, S.M., Kühn, S., Weygandt, M. and Stellmann, J.P.
Human Brain Mapping 42
(11): 3379-3395.
1 August 2021
Preoperative comparison of three anticholinergic drug scales in older adult patients and development of postoperative delirium: a prospective observational study.
Heinrich, M., Müller, A., Cvijan, A., Mörgeli, R., Kruppa, J., Winterer, G., Slooter, A.J.C. and Spies, C.D.
Drugs & Aging 38
(4): 347-354.
April 2021
Preoperative medication use and development of postoperative delirium and cognitive dysfunction.
Heinrich, M., Nottbrock, A., Borchers, F., Mörgeli, R., Kruppa, J., Winterer, G., Slooter, A.J.C. and Spies, C.
Clinical and Translational Science 14
(5): 1830-1840.
September 2021
Simultaneous T(2) and T(2)* mapping of multiple sclerosis lesions with radial RARE-EPI.
Herrmann, C., Els, A., Boehmert, L., Periquito, J., Eigentler, T.W., Millward, J., Waiczies, S., Kuchling, J., Paul, F. and Niendorf, T.
Magnetic Resonance in Medicine 86
(3): 1383-1402.
September 2021
Expression of a modified astrocytic glutamate transporter alleviates Huntington’s hypokinesia, promotes synaptic glutamate clearance and counteracts potentially adverse EAAT2 interactions.
Hirschberg, S., Dvorzhak, A., Rasooli-Nejad, S.M.A., Angelov, S., Kirchner, M., Mertins, P., Lättig-Tünnemann, G., Harms, C., Schmitz, D. and Grantyn, R.
bioRxiv
: 2020.09.17.302158.
26 March 2021
Inhibitory and agonistic autoantibodies directed against the ß(2)-adrenergic receptor in pseudoexfoliation syndrome and glaucoma.
Hohberger, B., Schlötzer-Schrehard, U., Mardin, C., Lämmer, R., Munoz, L., Kunze, R., Herrmann, M. and Wallukat, G.
Frontiers in Neuroscience 15
: 676579.
6 August 2021
Glial cell line‐derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia‐mediated glioma progression.
Huang, Y., Zhang, B., Haneke, H., Haage, V., Lubas, M., Yuan, Y., Xia, P., Motta, E., Nanvuma, C., Dzaye, O., Hu, F. and Kettenmann, H.
Journal of Neuroscience Research 99
(4): 1048-1063.
April 2021
MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari, F., Dahlmann, M., Sporbert, A., Ciolli Mattioli, C., Mari, T., Scholz, F., Timm, L., Twamley, S., Migotti, R., Walther, W., Dittmar, G., Rehm, A. and Stein, U.
Cellular and Molecular Life Sciences 78
(7): 3525-3542.
April 2021
Subiculum as a generator of sharp wave-ripples in the rodent hippocampus.
Imbrosci, B., Nitzan, N., McKenzie, S., Donoso, J.R., Swaminathan, A., Böhm, C., Maier, N and Schmitz, D.
Cell Reports 35
(3): 109021.
20 April 2021
Bioenergetic profiling of human pluripotent stem cells.
Inak, G., Henke, M.T. and Prigione, A.
Methods in Molecular Biology 2277
: 391-403.
2021
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G., Rybak-Wolf, A., Lisowski, P., Pentimalli, T.M., Jüttner, R., Glažar, P., Uppal, K., Bottani, E., Brunetti, D., Secker, C., Zink, A., Meierhofer, D., Henke, M.T., Dey, M., Ciptasari, U., Mlody, B., Hahn, T., Berruezo-Llacuna, M., Karaiskos, N., Di Virgilio, M., Mayr, J.A., Wortmann, S.B., Priller, J., Gotthardt, M., Jones, D.P., Mayatepek, E., Stenzel, W., Diecke, S., Kühn, R., Wanker, E.E., Rajewsky, N., Schuelke, M. and Prigione, A.
Nature Communications 12
(1): 1929.
26 March 2021
Sulfoxide-functionalized nanogels inspired by the skin penetration properties of DMSO.
Işık, D., Joshi, A.A., Guo, X., Rancan, F., Klossek, A., Vogt, A., Rühl, E., Hedtrich, S. and Klinger, D.
Biomaterials science 9
(3): 712-725.
7 February 2021
Assessing dysferlinopathy patients over three years with a new motor scale.
Jacobs, M., James, M.K., Lowes, L.P., Alfano, L.N., Eagle, M., Lofra, R.M., Moore, U., Feng, J., Rufibach, L.E., Rose, K., Duong, T., Bello, L., Pedrosa-Hernández, I., Holsten, S., Sakamoto, C., Canal, A., Práxedes, N.S.A., Thiele, S., Siener, C., Vandevelde, B., DeWolf, B., Maron, E., Guglieri, M., Hogrel, J.Y., Blamire, A.M., Carlier, P.G., Spuler, S., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Pestronk, A., Walter, M.C., Paradas, C., Stojkovic, T., Mori-Yoshimura, M., Bravver, E., Díaz-Manera, J., Pegoraro, E., Mendell, J.R., Mayhew, A.G. and Straub, V.
Annals of Neurology 89
(5): 967-978.
May 2021
Functional connectivity alterations of striato-cortical circuits in multiple sclerosis.
Jaeger, S., Paul, F. and Finke, C.
Multiple Sclerosis Journal 27
(9): 1469-1470.
1 August 2021
Diagnostik und Therapie von statinassoziierten Muskelsymptomen [Diagnostics and treatment of statin-associated muscle symptoms].
Kassner, U., Grunwald, S., Spira, D., Buchmann, N., Bobbert, T., Gazzerro, E., Hollstein, T., Spuler, S. and Steinhagen-Thiessen, E.
Internist 62
: 827-840.
August 2021
The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M., Farré i Díaz, C., Ofenbauer, A., Herzog, S. and Tursun, B.
Nucleic Acids Research 49
(4): e22.
26 February 2021
Chronic COVID-19 Syndrome and Chronic Fatigue Syndrome (ME/CFS) following the first pandemic wave in Germany - a first analysis of a prospective observational study.
Kedor, C., Freitag, H., Meyer-Arndt, L., Wittke, K., Zoller, t., Steinbeis, F., Haffke, M., Gordon, R., Heidecker, B., Volk, H.D., Skurk, C., Paul, F., Bellmann-Strobl, J. and Scheibenbogen, C.
medRxiv
: 2021.02.06.21249256.
8 February 2021
Glial cells: neuroglia.
Kettenmann, H. and Verkhratsky, A.
In:
Neuroscience in the 21st century : from basic to clinical.
Springer, New York, NY, 1-36.
ISBN 978-1-4614-6434-1
12 April 2021
UNC93B1 is widely expressed in the murine CNS and is required for neuroinflammation and neuronal injury induced by microRNA let-7b.
Klammer, M.G., Dzaye, O., Wallach, T., Krüger, C., Gaessler, D., Buonfiglioli, A., Derkow, K., Kettenmann, H., Brinkmann, M.M. and Lehnardt, S.
Frontiers in Immunology 12
: 715774.
September 2021
Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells.
Klockmeier, K., Silva Ramos, E., Raskó, T., Martí Pastor, A. and Wanker, E.E.
Journal of Molecular Biology 433
(19): 167184.
17 September 2021
Retinal thickness analysis in progressive multiple sclerosis patients treated with epigallocatechin gallate: optical coherence tomography results from the SUPREMES study.
Klumbies, K., Rust, R., Dörr, J., Konietschke, F., Paul, F., Bellmann-Strobl, J., Brandt, A.U. and Zimmermann, H.G.
Frontiers in Neurology 12
: 615790.
28 April 2021
Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds.
Kowalczyk, I., Lee, C., Schuster, E., Hoeren, J., Trivigno, V., Riedel, L., Görne, J., Wallingford, J.B., Hammes, A. and Feistel, K.
Development 148
(2): dev195008.
26 January 2021
Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L., Krupp, F., Harnett, D., Turko, P., Ambrozkiewicz, M.C., Sprink, T., Imami, K., Günnigmann, M., Zinnall, U., Vieira-Vieira, C.H., Schaub, T., Münster-Wandowski, A., Bürger, J., Borisova, E., Yamamoto, H., Rasin, M.R., Ohler, U., Beule, D., Mielke, T., Tarabykin, V., Landthaler, M., Kramer, G., Vida, I., Selbach, M. and Spahn, C.M.T.
Molecular Cell 81
(2): 304-322.
21 January 2021
Encephalitis patient-derived monoclonal GABA(A) receptor antibodies cause epileptic seizures.
Kreye, J., Wright, S.K., van Casteren, A., Stoeffler, L., Machule, M.L., Reincke, S.M., Nikolaus, M., van Hoof, S., Sanchez-Sendin, E., Homeyer, M.A., Gómez, C.C., Kornau, H.C., Schmitz, D., Kaindl, A.M., Boehm-Sturm, P., Mueller, S., Wilson, M.A., Upadhya, M.A., Dhangar, D.R., Greenhill, S., Woodhall, G., Turko, P., Vida, I., Garner, C.C., Wickel, J., Geis, C., Fukata, Y., Fukata, M. and Prüss, H.
Journal of Experimental Medicine 218
(11): e20210012.
1 November 2021
MEG reveals preference specific increases of sexual-image-evoked responses in paedophilic sexual offenders and healthy controls.
Krylova, M., Ristow, I., Marr, V., Borchardt, V., Li, M., Witzel, J., Drumkova, K., Harris, J.A., Zacharias, N., Schiltz, K., Amelung, T., Beier, K.M., Kruger, T.H.C., Ponseti, J., Schiffer, B., Walter, H., Kärgel, C. and Walter, M.
World Journal of Biological Psychiatry 22
(4): 257-270.
April 2021
Neuronal autophagy regulates presynaptic neurotransmission by controlling the axonal endoplasmic reticulum.
Kuijpers, M., Kochlamazashvili, G., Stumpf, A., Puchkov, D., Swaminathan, A., Lucht, M.T., Krause, E., Maritzen, T., Schmitz, D. and Haucke, V.
Neuron 109
(2): 299-313.
20 January 2021
Met and Cxcr4 cooperate to protect skeletal muscle stem cells against inflammation-induced damage during regeneration.
Lahmann, I., Griger, J., Chen, J.S., Zhang, Y., Schülke, M. and Birchmeier-Kohler, C.
eLife 10
: e57356.
5 August 2021
An oscillatory network controlling self-renewal of skeletal muscle stem cells.
Lahmann, I., Zhang, Y., Baum, K., Wolf, J. and Birchmeier, C.
Experimental Cell Research 409
(2): 112933.
15 December 2021
Generation of human brain organoids for mitochondrial disease modeling.
Le, S., Petersilie, L., Inak, G., Menacho-Pando, C., Kafitz, K.W., Rybak-Wolf, A., Rajewsky, N., Rose, C.R. and Prigione, A.
Journal of Visualized Experiments
(172): e62756.
21 June 2021
Technologies for profiling the impact of genomic variants on transcription factor binding.
Leiz, J., Rutkiewicz, M., Birchmeier, C., Heinemann, U. and Schmidt-Ott, K.M.
Medizinische Genetik 33
(2): 147-155.
14 August 2021
The Collaborative Research Center FONDA.
Leser, U., Hilbrich, M., Draxl, C., Eisert, P., Grunske, L., Hostert, P., Kainmüller, D., Kao, O., Kehr, B., Kehrer, T., Koch, C., Markl, V., Meyerhenke, H., Rabl, T., Reinefeld, A., Reinert, K., Ritter, K., Scheuermann, B., Schintke, F., Schweikardt, N. and Weidlich, M.
Datenbank-Spektrum 21
: 255-260.
November 2021
The somatosensory world of the African naked mole-rat.
Lewin, G.R., Smith, E.S.J., Reznick, J., Debus, K.Y., Barker, A.J. and Park, T.J.
Advances in Experimental Medicine and Biology 1319
(1319): 197-220.
24 August 2021
Beyond Ca(2+) signalling: the role of TRPV3 in the transport of NH(4).
Liebe, H., Liebe, F., Sponder, G., Hedtrich, S. and Stumpff, F.
Pflugers Archiv 473
(12): 1859-1884.
December 2021
Retinal optical coherence tomography and magnetic resonance imaging in neuromyelitis optica spectrum disorders and MOG-antibody associated disorders: an updated review.
Lin, T.Y., Chien, C., Lu, A., Paul, F. and Zimmermann, H.G.
Expert Review of Neurotherapeutics 21
(10): 1101-1123.
October 2021
Increased serum neurofilament light and thin ganglion cell-inner plexiform layer are additive risk factors for disease activity in early multiple sclerosis.
Lin, T.Y., Vitkova, V., Asseyer, S., Martorell Serra, I., Motamedi, S., Chien, C., Ditzhaus, M., Papadopoulou, A., Benkert, P., Kuhle, J., Bellmann-Strobl, J., Ruprecht, K., Paul, F., Brandt, A.U. and Zimmermann, H.G.
Neurology Neuroimmunology & Neuroinflammation 8
(5): e1051.
September 2021
Anti-MOG antibody-associated disorders: differences in clinical profiles and prognosis in Japan and Germany.
Liu, J., Mori, M., Zimmermann, H., Brandt, A., Havla, J., Tanaka, S., Sugimoto, K., Oji, S., Uzawa, A., Asseyer, S., Cooper, G., Jarius, S., Bellmann-Strobl, J., Ruprecht, K., Siebert, N., Masuda, H., Uchida, T., Ohtani, R., Nomura, K., Meinl, E., Kuempfel, T., Paul, F. and Kuwabara, S.
Journal of Neurology Neurosurgery and Psychiatry 92
(4): 377-383.
April 2021
Microglia sense neuronal activity via GABA in the early postnatal hippocampus.
Logiacco, F., Xia, P., Georgiev, S.V., Franconi, C., Chang, Y.J., Ugursu, B., Sporbert, A., Kühn, R., Kettenmann, H. and Semtner, M.
Cell Reports 37
(13): 110128.
28 December 2021
Practical recognition tools of immunoglobulin G serum antibodies against the myelin oligodendrocyte glycoprotein‐positive optic neuritis and its clinical implications.
Lotan, I., Oertel, F.C., Chien, C., Asseyer, S., Paul, F. and Stiebel‐Kalish, H.
Clinical and Experimental Neuroimmunology 12
(1): 42-53.
February 2021
Olig3 regulates early cerebellar development.
Lowenstein, E.D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A.E., Epifanova, E., Bladt, F., Isik, E.G., Buchert, S., Jia, S., Tarabykin, V. and Hernandez-Miranda, L.R.
eLife 10
: e64684.
16 February 2021
Cross-reactive CD4(+) T cells enhance SARS-CoV-2 immune responses upon infection and vaccination.
Loyal, L., Braun, J., Henze, L., Kruse, B., Dingeldey, M., Reimer, U., Kern, F., Schwarz, T., Mangold, M., Unger, C., Dörfler, F., Kadler, S., Rosowski, J., Gürcan, K., Uyar-Aydin, Z., Frentsch, M., Kurth, F., Schnatbaum, K., Eckey, M., Hippenstiel, S., Hocke, A., Müller, M.A., Sawitzki, B., Miltenyi, S., Paul, F., Mall, M.A., Wenschuh, H., Voigt, S., Drosten, C., Lauster, R., Lachman, N., Sander, L.E., Corman, V.M., Röhmel, J., Meyer-Arndt, L., Thiel, A. and Giesecke-Thiel, C.
Science 374
(6564): eabh1823.
8 October 2021
A simple spatial-independent associative and reversal learning task in mice.
Magara, F., Boury-Jamot, B. and Hörnberg, H.
Bio-protocol 11
(15): e4108.
5 August 2021
Age-related decline in murine heart and skeletal muscle performance is attenuated by reduced Ahnak1 expression.
Mahmoodzadeh, S., Koch, K., Schriever, C., Xu, J., Steinecker, M., Leber, J., Dworatzek, E., Purfürst, B., Kunz, S., Recchia, D., Canepari, M., Heuser, A., Di Francescantonio, S. and Morano, I.
Journal of Cachexia Sarcopenia and Muscle 12
: 1249-1265.
14 October 2021
Optogenetic silencing of neurotransmitter release with a naturally occurring invertebrate rhodopsin.
Mahn, M., Saraf-Sinik, I., Patil, P., Pulin, M., Bitton, E., Karalis, N., Bruentgens, F., Palgi, S., Gat, A., Dine, J., Wietek, J., Davidi, I., Levy, R., Litvin, A., Zhou, F., Sauter, K., Soba, P., Schmitz, D., Luthi, A., Rost, B.R., Wiegert, J.S. and Yizhar, O.
bioRxiv
: 2021.02.18.431673.
18 February 2021
Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin.
Mahn, M., Saraf-Sinik, I., Patil, P., Pulin, M., Bitton, E., Karalis, N., Bruentgens, F., Palgi, S., Gat, A., Dine, J., Wietek, J., Davidi, I., Levy, R., Litvin, A., Zhou, F., Sauter, K., Soba, P., Schmitz, D., Lüthi, A., Rost, B.R., Wiegert, J.S. and Yizhar, O.
Neuron 109
(10): 1621-1635.
19 May 2021
PatchPerPixMatch for automated 3d search of neuronal morphologies in light microscopy.
Mais, L., Hirsch, P., Managan, C., Wang, K., Rokicki, K., Svirskas, R.R., Dickson, B.J., Korff, W., Rubin, G.M., Ihrke, G., Meissner, G.W. and Kainmueller, D.
bioRxiv
: 2021.07.23.453511.
26 July 2021
Knock-in mice expressing a 15-lipoxygenating Alox5 mutant respond differently to experimental inflammation than reported mice.
Marbach-Breitrück, E., Rohwer, N., Infante-Duarte, C., Romero-Suarez, S., Labuz, D., Machelska, H., Kutzner, L., Schebb, N.H., Rothe, M., Reddanna, P., Weylandt, K.H., Wieler, L.H, Heydeck, D. and Kuhn, H.
Metabolites 11
(10): 698.
12 October 2021
Induced neurons from germ cells in Caenorhabditis elegans.
Marchal, I. and Tursun, B.
Frontiers in Neuroscience 15
: 771687.
3 December 2021
Disability outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.
Marignier, R., Bennett, J.L., Kim, H.J., Weinshenker, B.G., Pittock, S.J., Wingerchuk, D., Fujihara, K., Paul, F., Cutter, G.R., Green, A.J., Aktas, O., Hartung, H.P., Lublin, F.D., Williams, I.M., Drappa, J., She, D., Cimbora, D., Rees, W., Smith, M., Ratchford, J.N., Katz, E. and Cree, B.A.C.
Neurology Neuroimmunology & Neuroinflammation 8
(3): e978.
May 2021
Myelin-oligodendrocyte glycoprotein antibody-associated disease.
Marignier, R., Hacohen, Y., Cobo-Calvo, A., Pröbstel, A.K., Aktas, O., Alexopoulos, H., Amato, M.P., Asgari, N., Banwell, B., Bennett, J., Brilot, F., Capobianco, M., Chitnis, T., Ciccarelli, O., Deiva, K., De Sèze, J., Fujihara, K., Jacob, A., Kim, H.J., Kleiter, I., Lassmann, H., Leite, M.I., Linington, C., Meinl, E., Palace, J., Paul, F., Petzold, A., Pittock, S., Reindl, M., Sato, D.K., Selmaj, K., Siva, A., Stankoff, B., Tintore, M., Traboulsee, A., Waters, P., Waubant, E., Weinshenker, B., Derfuss, T., Vukusic, S. and Hemmer, B.
Lancet Neurology 20
(9): 762-772.
September 2021
Identification of disease-relevant modulators of the SHH pathway in the developing brain.
Mecklenburg, N., Kowalczyk, I., Witte, F., Görne, J., Laier, A., Mamo, T.M., Gonschior, H., Lehmann, M., Richter, M., Sporbert, A., Purfürst, B., Hübner, N. and Hammes, A.
Development 148
(17): dev199307.
September 2021
Charcot-Marie-Tooth mutation in glycyl-tRNA synthetase stalls ribosomes in a pre-accommodation state and activates integrated stress response.
Mendonsa, S., von Kuegelgen, N., Bujanic, L. and Chekulaeva, M.
Nucleic Acids Research 49
(17): 10007-10017.
27 September 2021
Lymphocyte access to lymphoma is impaired by high endothelial venule regression.
Menzel, L., Zschummel, M., Crowley, T., Franke, V., Grau, M., Ulbricht, C., Hauser, A., Siffrin, V., Bajénoff, M., Acton, S.E., Akalin, A., Lenz, G., Willimsky, G., Höpken, U.E. and Rehm, A.
Cell Reports 37
(4): 109878.
26 October 2021
Neural processes of psychological stress and relaxation predict the future evolution of quality of life in multiple sclerosis.
Meyer-Arndt, L., Schmitz-Hübsch, T., Bellmann-Strobl, J., Brandt, A.U., Haynes, J.D., Gold, S.M., Paul, F. and Weygandt, M.
Frontiers in Neurology 12
: 753107.
23 November 2021
Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure.
Michalick, L., Weidenfeld, S., Grimmer, B., Fatykhova, D., Solymosi, P.D., Behrens, F., Dohmen, M., Brack, M.C., Schulz, S., Thomasch, E., Simmons, S., Müller-Redetzky, H., Suttorp, N., Kurth, F., Neudecker, J., Toennies, M., Bauer, T.T., Eggeling, S., Corman, V.M., Hocke, A.C., Witzenrath, M., Hippenstiel, S. and Kuebler, W.M.
European Respiratory Journal 57
(3): 2002384.
11 March 2021
Miyoshi myopathy and limb girdle muscular dystrophy R2 are the same disease.
Moore, U., Gordish, H., Diaz-Manera, J., James, M.K., Mayhew, A.G., Guglieri, M., Torron, R.F., Rufibach, L.E., Feng, J., Blamire, A.M., Carlier, P.G., Spuler, S., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Pestronk, A., Walter, M.C., Paradas, C., Stojkovic, T., Mori-Yoshimura, M., Bravver, E., Pegoraro, E., Lowes, L.P., Mendell, J.R., Bushby, K. and Straub, V.
Neuromuscular Disorders 31
(4): 265-280.
April 2021
Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca, P., Jäntti, N.Z., Godbole, R., Sommer, C., Jacquemet, G., Al-Akhrass, H., Conway, J.R.W., Kronqvist, P., Kallionpää, R.E., Oliveira-Ferrer, L., Cervero, P., Linder, S., Aepfelbacher, M., Zauber, H., Rae, J., Parton, R.G., Disanza, A., Scita, G., Mayor, S., Selbach, M., Veltel, S. and Ivaska, J.
Nature Cell Biology 23
(10): 1073-1084.
October 2021
Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Nikolay, R., Hilal, T., Schmidt, S., Qin, B., Schwefel, D., Vieira-Vieira, C.H., Mielke, T., Bürger, J., Loerke, J., Amikura, K., Flügel, T., Ueda, T., Selbach, M., Deuerling, E. and Spahn, C.M.T.
Molecular Cell 81
(6): 1200-1215.
18 March 2021
Accelerating clinical research in neuromyelitis optica spectrum disorders.
Oertel, F.C. and Paul, F.
Clinical and Experimental Neuroimmunology 12
(2): 89-91.
May 2021
Differenzialdiagnostik autoimmun-entzündlicher Rückenmarkserkrankungen [Differential diagnostics of autoimmune inflammatory spinal cord diseases].
Oertel, F.C., Scheel, M., Chien, C., Bischof, A., Finke, C. and Paul, F.
Nervenarzt 92
(4): 293-306.
April 2021
Retinal optical coherence tomography in neuromyelitis optica.
Oertel, F.C., Specovius, S., Zimmermann, H.G., Chien, C., Motamedi, S., Bereuter, C., Cook, L., Lana Peixoto, M.A., Fontanelle, M.A., Kim, H.J., Hyun, J.W., Palace, J., Roca-Fernandez, A., Leite, M.I., Sharma, S., Ashtari, F., Kafieh, R., Dehghani, A., Pourazizi, M., Pandit, L., D'Cunha, A., Aktas, O., Ringelstein, M., Albrecht, P., May, E., Tongco, C., Leocani, L., Pisa, M., Radaelli, M., Martinez-Lapiscina, E.H., Stiebel-Kalish, H., Siritho, S., de Seze, J., Senger, T., Havla, J., Marignier, R., Cobo-Calvo, A., Bichuetti, D., Tavares, I.M., Asgari, N., Soelberg, K., Altintas, A., Yildirim, R., Tanriverdi, U., Jacob, A., Huda, S., Rimler, Z., Reid, A., Mao-Draayer, Y., Soto de Castillo, I., Petzold, A., Green, A.J., Yeaman, M.R., Smith, T., Brandt, A.U. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 8
(6): e1068.
November 2021
The C. elegans pseudogene sspt-16 (F55A3.7) is required to safeguard germ cells against reprogramming.
Ofenbauer, A., Kraus, C.M. and Tursun, B.
microPublication Biology 2021
18 May 2021
Chances and challenges of a long-term data repository in multiple sclerosis: 20th birthday of the German MS registry.
Ohle, L.M., Ellenberger, D., Flachenecker, P., Friede, T., Haas, J., Hellwig, K., Parciak, T., Warnke, C., Paul, F., Zettl, U.K. and Stahmann, A.
Scientific Reports 11
(1): 13340.
25 June 2021
SynaptoPAC, an optogenetic tool for induction of presynaptic plasticity.
Oldani, S., Moreno-Velasquez, L., Faiss, L., Stumpf, A., Rosenmund, C., Schmitz, D. and Rost, B.R.
Journal of Neurochemistry 156
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February 2021
Recruitment of release sites underlies chemical presynaptic potentiation at hippocampal mossy fiber boutons.
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PLoS Biology 19
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21 June 2021
SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of multiple sclerosis patients.
Ostendorf, L., Dittert, P., Biesen, R., Duchow, A., Stiglbauer, V., Ruprecht, K., Bellmann-Strobl, J., Seelow, D., Stenzel, W., Niesner, R.A., Hauser, A.E., Paul, F. and Radbruch, H.
Scientific Reports 11
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13 May 2021
Cultural bias in motor function patterns: potential relevance for predictive, preventive, and personalized medicine.
Otte, K., Ellermeyer, T., Suzuki, M., Röhling, H.M., Kuroiwa, R., Cooper, G., Mansow-Model, S., Mori, M., Zimmermann, H., Brandt, A.U., Paul, F., Hirano, S., Kuwabara, S. and Schmitz-Hübsch, T.
EPMA Journal 12
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March 2021
C3 and C4 complement levels in AQP4-IgG-positive NMOSD and in MOGAD.
Pache, F., Ringelstein, M., Aktas, O., Kleiter, I., Jarius, S., Siebert, N., Bellmann-Strobl, J., Paul, F. and Ruprecht, K.
Journal of Neuroimmunology 360
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15 November 2021
Lateral geniculate nucleus volume changes after optic neuritis in neuromyelitis optica: a longitudinal study.
Papadopoulou, A., Oertel, F.C., Chien, C., Kuchling, J., Zimmermann, H.G., Siebert, N., Motamedi, S., D'Souza, M., Asseyer, S., Bellmann-Strobl, J., Ruprecht, K., Chakravarty, M.M., Scheel, M., Magon, S., Wuerfel, J., Paul, F. and Brandt, A.U.
NeuroImage: Clinical 30
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4 March 2021
African naked mole-rats demonstrate extreme tolerance to hypoxia and hypercapnia.
Park, T.J., Smith, E.S.J., Reznick, J., Bennett, N.C., Applegate, D.T., Larson, J. and Lewin, G.R.
Advances in Experimental Medicine and Biology 1319
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24 August 2021
Spinal cord and brain MRI should be routinely performed during follow-up in patients with NMOSD - commentary.
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Multiple Sclerosis Journal 27
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1 January 2021
Optical coherence tomography in multiple sclerosis: a 3-year prospective multicenter study.
Paul, F., Calabresi, P.A., Barkhof, F., Green, A.J., Kardon, R., Sastre-Garriga, J., Schippling, S., Vermersch, P., Saidha, S., Gerendas, B.S., Schmidt-Erfurth, U., Agoropoulou, C., Zhang, Y., Seifer, G. and Petzold, A.
Annals of Clinical and Translational Neurology 8
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14 December 2021
Effect of nabiximols on goal attainment scale scores in patients with treatment-resistant multiple sclerosis spasticity.
Paul, F. and Silván, C.V.
Neurodegenerative Disease Management 11
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1 March 2021
Artificial intelligence extension of the OSCAR-IB criteria.
Petzold, A., Albrecht, P., Balcer, L., Bekkers, E., Brandt, A.U., Calabresi, P.A., Deborah, O.G., Graves, J.S., Green, A., Keane, P.A., Nij Bijvank, J.A., Sander, J.W., Paul, F., Saidha, S., Villoslada, P., Wagner, S.K. and Yeh, E.A.
Annals of Clinical and Translational Neurology 8
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July 2021
Astrocytes and oligodendrocytes in the thalamus jointly maintain synaptic activity by supplying metabolites.
Philippot, C., Griemsmann, S., Jabs, R., Seifert, G., Kettenmann, H. and Steinhäuser, C.
Cell Reports 34
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19 January 2021
Rabies anterograde monosynaptic tracing reveals organization of spinal sensory circuits.
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bioRxiv
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11 February 2021
The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains.
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15 March 2021
FRC-QE: a robust and comparable 3D microscopy image quality metric for cleared organoids.
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Bioinformatics 37
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15 September 2021
In vivo detection of teriflunomide-derived fluorine signal during neuroinflammation using fluorine MR spectroscopy.
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1 January 2021
Pentafluorosulfanyl (SF(5)) as a superior (19)F magnetic resonance reporter group: signal detection and biological activity of teriflunomide derivatives.
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26 November 2021
Early days of tenascin-R research: two approaches discovered and shed light on tenascin-R.
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Frontiers in Immunology 11
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8 January 2021
Expanding the phenotype of NUP85 mutations beyond nephrotic syndrome to primary autosomal recessive microcephaly and Seckel syndrome spectrum disorders.
Ravindran, E., Jühlen, R., Vieira-Vieira, C.H., Ha, T., Salzberg, Y., Fichtman, B., Luise-Becker, L., Martins, N., Picker-Minh, S., Bessa, P., Arts, P., Jackson, M.R., Taranath, A., Kamien, B., Barnett, C., Li, N., Tarabykin, V., Stoltenburg-Didinger, G., Harel, A., Selbach, M., Dickmanns, A., Fahrenkrog, B., Hu, H., Scott, H. and Kaindl, A.M.
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15 November 2021
A sweet story of metabolic innovation in the naked mole-rat.
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24 August 2021
COVID-19: a simple statistical model for predicting intensive care unit load in exponential phases of the disease.
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Scientific Reports 11
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3 March 2021
Foveal changes in aquaporin‐4 antibody seropositive neuromyelitis optica spectrum disorder are independent of optic neuritis and not overtly progressive.
Roca-Fernández, A., Oertel, F.C., Yeo, T, Motamedi, S., Probert, F., Craner, M.J., Sastre-Garriga, J., Zimmermann, H.G., Asseyer, S., Kuchling, J., Bellmann-Strobl, J., Ruprecht, K., Leite, M.I., Paul, F., Brandt, A.U. and Palace, J.
European Journal of Neurology 28
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July 2021
A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
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On the distribution of spinal premotor interneurons.
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bioRxiv
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11 February 2021
Validation of computer-adaptive contrast sensitivity as a tool to assess visual impairment in multiple sclerosis patients.
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23 February 2021
Mitochondrial bioenergetics and neurodegeneration: a paso doble.
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April 2021
Probabilistic deep learning for instance segmentation.
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Epigallocatechin gallate in progressive MS: a randomized, placebo-controlled trial.
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Neurology Neuroimmunology & Neuroinflammation 8
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May 2021
Viruses and endogenous retroviruses as roots for neuroinflammation and neurodegenerative diseases.
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Reduction of cortical parvalbumin expressing GABAergic interneurons in a rodent hyperoxia model of preterm birth brain injury with deficits in social behavior and cognition.
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Small, seeding-competent huntingtin fibrils are prominent aggregate species in brains of zQ175 Huntington's disease knock-in mice.
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Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder.
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1 May 2021
Longitudinal analysis of primary and secondary factors related to fatigue in multiple sclerosis.
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Anti-aquaporin 4 IgG is not associated with any clinical disease characteristics in Neuromyelitis Optica Spectrum Disorder.
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Spinocerebellar ataxia type 14: refining clinicogenetic diagnosis in a rare adult-onset disorder.
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USH2A is a Meissner's corpuscle protein necessary for normal vibration sensing in mice and humans.
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Fingolimod therapy in multiple sclerosis leads to the enrichment of a subpopulation of aged NK cells.
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CellFIE: CRISPR- and cell fusion-based two-hybrid interaction mapping of endogenous proteins.
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Polysialic acid in the rat brainstem and thoracolumbar spinal cord: distribution, cellular location and comparison with mouse.
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Inebilizumab in AQP4-Ab-positive neuromyelitis optica spectrum disorder.
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Contribution of tissue inflammation and blood-brain barrier disruption to brain softening in a mouse model of multiple sclerosis.
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Chances and challenges of registry-based pharmacovigilance in multiple sclerosis: lessons learnt from the implementation of the multicenter REGIMS registry.
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The Asian and African/Caribbean AQP4-NMOSD patient outcomes according to self-identified race and place of residence.
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A window into the future? MRI for evaluation of neuromyelitis optica spectrum disorder throughout the disease course.
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Cognitive impairment in multiple system atrophy is related to white matter damage detected by the T1-weighted/T2-weighted ratio.
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Magnetic resonance T1w/T2w ratio in the middle cerebellar peduncle might be a sensitive biomarker for multiple system atrophy.
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Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study.
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Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease.
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Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study.
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Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils.
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Peripheral mechanisms of arthritic pain: a proposal to leverage large animals for in vitro studies.
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Visual system damage and network maladaptation are associated with cognitive performance in neuromyelitis optica spectrum disorders.
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Longitudinal ultra-high field MRI of brain lesions in neuromyelitis optica spectrum disorders.
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Considerations for mean upper cervical cord area implementation in a longitudinal MRI setting: methods, interrater reliability, and MRI quality control.
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Quantitative multi-parameter mapping optimized for the clinical routine.
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PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
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HMGXB4 targets Sleeping Beauty transposition to vertebrate germinal stem sells.
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Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.
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Polypeptide-corticosteroid conjugates as a topical treatment approach to psoriasis.
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Association between fatigue and motor exertion in patients with multiple sclerosis - a prospective study.
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Emerging drugs for the treatment of neuromyelitis optica.
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Initiating a new national epilepsy surgery program: experiences gathered in Georgia.
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Brain iron and metabolic abnormalities in C19orf12 mutation carriers: a 7.0 tesla MRI study in mitochondrial membrane protein-associated neurodegeneration.
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High-dose vitamin D supplementation in multiple sclerosis - results from the randomized EVIDIMS (efficacy of vitamin D supplementation in multiple sclerosis) trial.
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Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
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Harnessing spatial homogeneity of neuroimaging data: patch individual filter layers for CNNs.
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23 July 2020
Aggressive multiple sclerosis - a matter of measurement and timing.
Ellenberger, D., Flachenecker, P., Fneish, F., Frahm, N., Hellwig, K., Paul, F., Stahmann, A., Warnke, C., Rommer, P.S. and Zettl, U.K.
Brain 143
(11): e97.
November 2020
Is benign MS really benign? What a meaningful classification beyond the EDSS must take into consideration.
Ellenberger, D., Flachenecker, P., Haas, J., Hellwig, K., Paul, F., Stahmann, A., Warnke, C., Zettl, U.K. and Rommer, P.S.
Multiple Sclerosis and Related Disorders 46
: 102485.
November 2020
Neurofibromatosis 1 - mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects.
Elmadany, N., Logiacco, F., Buonfiglioli, A., Haage, V., Wright-Jin, E.C., Schattenberg, A., Papawassiliou, R., Kettenmann, H., Semtner, M. and Gutmann, D.H.
Neurobiology of Disease 144
: 105030.
October 2020
The VGF-derived peptide TLQP21 impairs purinergic control of chemotaxis and phagocytosis in mouse microglia.
Elmadany, N., de Almeida Sassi, F., Wendt, S., Logiacco, F., Visser, J., Haage, V., Perez Hernandez, D., Mertins, P., Hambardzumyan, D., Wolf, S., Kettenmann, H. and Semtner, M.
Journal of Neuroscience 40
(17): 3320-3331.
22 April 2020
Investigation of TEMPO partitioning in different skin models as measured by EPR spectroscopy - insight into the stratum corneum.
Elpelt, A., Ivanov, D., Nováčková, A., Kováčik, A., Sochorová, M., Saeidpour, S., Teutloff, C., Lohan, S.B., Lademann, J., Vávrová, K., Hedtrich, S. and Meinke, M.C.
Journal of Magnetic Resonance 310
: 106637.
January 2020
Is APOE ε4 associated with cognitive performance in early MS?
Engel, S., Graetz, C., Salmen, A., Muthuraman, M., Toenges, G., Ambrosius, B., Bayas, A., Berthele, A., Heesen, C., Klotz, L., Kümpfel, T., Linker, R.A., Meuth, S.G., Paul, F., Stangel, M., Tackenberg, B., Then Bergh, F., Tumani, H., Weber, F., Wildemann, B., Zettl, U.K., Antony, G., Bittner, S., Groppa, S., Hemmer, B., Wiendl, H., Gold, R., Zipp, F., Lill, C.M. and Luessi, F.
Neurology Neuroimmunology & Neuroinflammation 7
(4): e728.
July 2020
Generation of sharp wave-ripple events by disinhibition.
Evangelista, R., Cano, G., Cooper, C., Schmitz, D., Maier, N. and Kempter, R.
Journal of Neuroscience 40
(41): 7811-7836.
7 October 2020
Binding patterns and functional properties of human antibodies to AQP4 and MOG on murine optic nerve and retina.
Faissner, S., Graz, F., Reinehr, S., Petrikowski, L., Haupeltshofer, S., Ceylan, U., Stute, G., Winklmeier, S., Pache, F., Paul, F., Ruprecht, K., Meinl, E., Dick, H.B., Gold, R., Kleiter, I. and Joachim, S.C.
Journal of Neuroimmunology 342
: 577194.
15 May 2020
Loss of Piccolo function in rats induces cerebellar network dysfunction and Pontocerebellar Hypoplasia type 3-like phenotypes.
Falck, J., Bruns, C., Hoffmann-Conaway, S., Straub, I., Plautz, E.J., Orlando, M., Munawar, H., Rivalan, M., Winter, Y., Izsvák, Z., Schmitz, D., Hamra, F.K., Hallermann, S., Curtis Garner, C. and Ackermann, F.
Journal of Neuroscience 40
(14): 2943-2959.
1 April 2020
Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C., Urzi, A., Vidal, R., Kunz, S., Ruffault, P.L., Kabuss, L., Hube, I., Gazzerro, E., Birchmeier, C., Spuler, S., Sauer, S. and Gouti, M.
Cell Stem Cell 26
(2): 172-186.
6 February 2020
Identifying progression in multiple sclerosis: new perspectives.
Filippi, M., Preziosa, P., Langdon, D., Lassmann, H., Paul, F., Rovira, À., Schoonheim, M.M., Solari, A., Stankoff, B. and Rocca, M.A.
Annals of Neurology 88
(3): 438-452.
September 2020
Exploiting a PAX3-FOXO1-induced synthetic lethal ATR dependency for rhabdomyosarcoma therapy.
García, H.D., Bei, Y., von Stebut, J., Ibáñez, G., Imami, K., Gürgen, D., Rolff, J., Helmsauer, K., Timme, N., Bardinet, V., Chamorro González, R., MacArthur, I.C., Pusch, F.F., Chen, C.Y., Schulz, J., Wengner, A.M., Furth, C., Lala, B., Eggert, A., Seifert, G., Hundsoerfer, P., Kirchner, M., Mertins, P., Selbach, M., Lissat, A., Schulte, J.H., Haase, K., Scheer, M., Ortiz, M.V. and Henssen, A.G.
bioRxiv
: 2020.12.04.411413.
2020
Genetic determinants of the humoral immune response in MS.
Gasperi, C., Andlauer, T.F.M., Keating, A., Knier, B., Klein, A., Pernpeintner, V., Lichtner, P., Gold, R., Zipp, F., Then Bergh, F., Stangel, M., Tumani, H., Wildemann, B., Wiendl, H., Bayas, A., Kümpfel, T., Zettl, U.K., Linker, R.A., Ziemann, U., Knop, M., Warnke, C., Friese, M.A., Paul, F., Tackenberg, B., Berthele, A. and Hemmer, B.
Neurology Neuroimmunology & Neuroinflammation 7
(5): e827.
September 2020
Notch1 in cancer therapy: possible clinical implications and challenges.
Gharaibeh, L., Elmadany, N., Alwosaibai, K. and Alshaer, W.
Molecular Pharmacology 98
(5): 559-576.
1 November 2020
Frequency of autoimmune disorders and autoantibodies in European patients with neuromyelitis optica spectrum disorders.
Gkaniatsou, T., Papadopoulou, A., Paul, F., Brandt, A.U. and Oertel, F.C.
Acta Neurologica Belgica 120
(1): 223-225.
February 2020
Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
Scientific Reports 10
: 2158.
7 February 2020
A survey of travel behaviour among scientists in Germany and the potential for change.
Haage, V.
eLife 9
: e56765.
28 May 2020
Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains.
Haenig, C., Atias, N., Taylor, A.K., Mazza, A., Schaefer, M.H., Russ, J., Riechers, S.P., Jain, S., Coughlin, M., Fontaine, J.F., Freibaum, B.D., Brusendorf, L., Zenkner, M., Porras, P., Stroedicke, M., Schnoegl, S., Arnsburg, K., Boeddrich, A., Pigazzini, L., Heutink, P., Taylor, J.P., Kirstein, J., Andrade-Navarro, M.A., Sharan, R. and Wanker, E.E.
Cell Reports 32
(7): 108050.
18 August 2020
Vascular cognitive impairment in the mouse reshapes visual, spatial network functional connectivity.
Hall, G.R., Boehm-Sturm, P., Dirnagl, U., Finke, C., Foddis, M., Harms, C., Koch, S.P., Kuchling, J., Madan, C.R., Mueller, S., Sassi, C., Sotiropoulos, S.N., Trueman, R.C., Wallis, M., Yildirim, F. and Farr, T.D.
bioRxiv
: 2020.11.04.366294.
5 November 2020
The mechanotransduction protein STOML3 is required for functional plasticity following peripheral nerve regeneration.
Haseleu, J., Walcher, J. and Lewin, G.R.
bioRxiv
: 2020.11.10.367748.
10 November 2020
Transdiagnostic hippocampal damage patterns in neuroimmunological disorders.
Heine, J., Prüß, H., Scheel, M., Brandt, A.U., Gold, S.M., Bartsch, T., Paul, F. and Finke, C.
NeuroImage: Clinical 28
: 102515.
2020
Radiological, chemical, and pharmacological cholinergic system parameters and neurocognitive disorders in older presurgical adults.
Heinrich, M., Müller, A., Lammers-Lietz, F., Borchers, F., Mörgeli, R., Kruppa, J., Zacharias, N., Winterer, G., Slooter, A.J.C. and Spies, C.D.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences 76
(6): 1029-1036.
June 2020
Addiction Research Consortium: losing and regaining control over drug intake (ReCoDe) - from trajectories to mechanisms and interventions.
Heinz, A., Kiefer, F., Smolka, M.N., Endrass, T., Beste, C., Beck, A., Liu, S., Genauck, A., Romund, L., Banaschewski, T., Bermpohl, F., Deserno, L., Dolan, R.J., Durstewitz, D., Ebner-Priemer, U., Flor, H., Hansson, A.C., Heim, C., Hermann, D., Kiebel, S., Kirsch, P., Kirschbaum, C., Koppe, G., Marxen, M., Meyer-Lindenberg, A., Nagel, W.E., Noori, H.R., Pilhatsch, M., Priller, J., Rietschel, M., Romanczuk-Seiferth, N., Schlagenhauf, F., Sommer, W.H., Stallkamp, J., Ströhle, A., Stock, A.K., Winterer, G., Winter, C., Walter, H., Witt, S., Vollstädt-Klein, S., Rapp, M.A., Tost, H. and Spanagel, R.
Addiction Biology 25
(2): e12866.
March 2020
Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study.
Heitmann, H., Haller, B., Tiemann, L., Mühlau, M., Berthele, A., Tölle, T.R., Salmen, A., Ambrosius, B., Bayas, A., Asseyer, S., Hartung, H.P., Heesen, C., Stangel, M., Wildemann, B., Haars, S., Groppa, S., Luessi, F., Kümpfel, T., Nischwitz, S., Meuth, S.G., Klotz, L., Linker, R.A., Zettl, U.K., Ziemann, U., Tumani, H., Tackenberg, B., Zipp, F., Wiendl, H., Gold, R., Hemmer, B. and Ploner, M.
Pain 161
(4): 787-796.
April 2020
Epidemiology of neuromyelitis optica spectrum disorder and its prevalence and incidence worldwide.
Hor, J.Y., Asgari, N., Nakashima, I., Broadley, S.A., Leite, M.I., Kissani, N., Jacob, A., Marignier, R., Weinshenker, B.G., Paul, F., Pittock, S.J., Palace, J., Wingerchuk, D.M., Behne, J.M., Yeaman, M.R. and Fujihara, K.
Frontiers in Neurology 11
: 501.
26 June 2020
A multi-modal virtual reality treadmill intervention for enhancing mobility and cognitive function in people with multiple sclerosis: protocol for a randomized controlled trial.
Hsieh, K.L., Mirelman, A., Shema-Shiratzky, S., Galperin, I., Regev, K., Shen, S., Schmitz-Hübsch, T., Karni, A., Paul, F., Devos, H., Sosnoff, J.J. and Hausdorff, J.M.
Contemporary Clinical Trials 97
: 106122.
October 2020
Down-regulation of Aquaporin-1 mediates a microglial phenotype switch affecting glioma growth.
Hu, F., Huang, Y., Semtner, M., Zhao, K., Tan, Z., Dzaye, O., Kettenmann, H., Shu, K. and Lei, T.
Experimental Cell Research 396
(2): 112323.
15 November 2020
MEK inhibitor trametinib attenuates neuroinflammation and cognitive deficits following traumatic brain injury in mice.
Huang, Y., Li, Q., Tian, H., Yao, X., Bakina, O., Zhang, H., Lei, T. and Hu, F.
American Journal of Translational Research 12
(10): 6351-6365.
15 October 2020
Synergistic toll-like receptor 3/9 signaling affects properties and impairs glioma-promoting activity of microglia.
Huang, Y., Zhang, Q., Lubas, M., Yuan, Y., Yalcin, F., Efe, I.E., Xia, P., Motta, E., Buonfiglioli, A., Lehnardt, S., Dzaye, O., Flueh, C., Synowitz, M., Hu, Feng and Kettenmann, H.
Journal of Neuroscience 40
(33): 6428-6443.
12 August 2020
Emotional experience in patients with clinically isolated syndrome and early multiple sclerosis.
Hälbig, T.D., Wüstenberg, T., Giess, R.M., Kunte, H., Bellmann-Strobl, J., Ruprecht, K. and Paul, F.
European Journal of Neurology 27
(8): 1537-1545.
August 2020
Rescue of oxytocin response and social behaviour in a mouse model of autism.
Hörnberg, H., Pérez-Garci, E., Schreiner, D., Hatstatt-Burklé, L., Magara, F., Baudouin, S., Matter, A., Nacro, K., Pecho-Vrieseling, E. and Scheiffele, P.
Nature 584
(7820): 252-256.
13 August 2020
Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury.
Ifuku, M., Hinkelmann, L., Kuhrt, L.D., Efe, I.E., Kumbol, V., Buonfiglioli, A., Krüger, C., Jordan, P., Fulde, M., Noda, M., Kettenmann, H. and Lehnardt, S.
Acta Neuropathologica Communications 8
(1): 159.
10 September 2020
Investigation of visual system involvement in spinocerebellar ataxia type 14.
Ihl, T., Kadas, E.M., Oberwahrenbrock, T., Endres, M., Klockgether, T., Schroeter, J., Brandt, A.U., Paul, F., Minnerop, M., Doss, S., Schmitz-Hübsch, T. and Zimmermann, H.G.
Cerebellum 19
(4): 469-482.
August 2020
Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients.
Jarius, S., Lechner, C., Wendel, E.M., Baumann, M., Breu, M., Schimmel, M., Karenfort, M., Marina, A.D., Merkenschlager, A., Thiels, C., Blaschek, A., Salandin, M., Leiz, S., Leypoldt, F., Pschibul, A., Hackenberg, A., Hahn, A., Syrbe, S., Strautmanis, J., Häusler, M., Krieg, P., Eisenkölbl, A., Stoffels, J., Eckenweiler, M., Ayzenberg, I., Haas, J., Höftberger, R., Kleiter, I., Korporal-Kuhnke, M., Ringelstein, M., Ruprecht, K., Siebert, N., Schanda, K., Aktas, O., Paul, F., Reindl, M., Wildemann, B. and Rostásy, K.
Journal of Neuroinflammation 17
(1): 262.
3 September 2020
Neuromyelitis optica.
Jarius, S., Paul, F., Weinshenker, B.G., Levy, M., Kim, H.J. and Wildemann, B.
Nature Reviews Disease Primers 6
(1): 85.
22 October 2020
Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients.
Jarius, S., Pellkofer, H., Siebert, N., Korporal-Kuhnke, M., Hümmert, M.W., Ringelstein, M., Rommer, P.S., Ayzenberg, I., Ruprecht, K., Klotz, L., Asgari, N., Zrzavy, T., Höftberger, R., Tobia, R., Buttmann, M., Fechner, K., Schanda, K., Weber, M., Asseyer, S., Haas, J., Lechner, C., Kleiter, I., Aktas, O., Trebst, C., Rostasy, K., Reindl, M., Kümpfel, T., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 17
(1): 261.
3 September 2020
Impact of intercellular crosstalk between epidermal keratinocytes and dermal fibroblasts on skin homeostasis.
Jevtić, M., Löwa, A., Nováčková, A., Kováčik, A., Kaessmeyer, S., Erdmann, G., Vávrová, K. and Hedtrich, S.
Biochimica et Biophysica Acta - Molecular Cell Research 1867
(8): 118722.
August 2020
Optic chiasm measurements may be useful markers of anterior optic pathway degeneration in neuromyelitis optica spectrum disorders.
Juenger, V., Cooper, G., Chien, C., Chikermane, M., Oertel, F.C., Zimmermann, H., Ruprecht, K., Jarius, S., Siebert, N., Kuchling, J., Papadopoulou, A., Asseyer, S., Bellmann-Strobl, J., Paul, F., Brandt, A.U. and Scheel, M.
European Radiology 30
(9): 5048-5058.
September 2020
The CONDOR pipeline for simultaneous knockdown of multiple genes identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M., Díaz, C.F., Ofenbauer, A. and Tursun, B.
bioRxiv
: 2020.09.01.276972.
1 September 2020
Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M., Franke, V., Brandt, B., Lowenstein, E.D., Schöwel, V., Spuler, S., Akalin, A. and Birchmeier, C.
Nature Communications 11
: 6375.
11 December 2020
Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation.
Kim, M., Zhang, Y. and Birchmeier, C.
bioRxiv
: 2020.12.22.424062.
22 December 2020
Human cerebrospinal fluid monoclonal LGI1 autoantibodies increase neuronal excitability.
Kornau, H.C., Kreye, J., Stumpf, A., Fukata, Y., Parthier, D., Sammons, R.P., Imbrosci, B., Kurpjuweit, S., Kowski, A.B., Fukata, M., Prüss, H. and Schmitz, D.
Annals of Neurology 87
(3): 405-418.
March 2020
A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
Kreye, J., Reincke, S.M., Kornau, H.C., Sanchez-Sendin, E., Corman, V.M., Liu, H., Yuan, M., Wu, N.C., Zhu, X., Lee, C.C.D., Trimpert, J., Hoeltje, M., Dietert, K., Stoeffler, L., von Wardenburg, N., van Hoof, S., Homeyer, M.A., Hoffmann, J., Abdelgawad, A., Gruber, A.D., Bertzbach, L.D., Vladimirova, D., Li, L.Y., Barthel, P.C., Skriner, K., Hocke, A.C., Hippenstiel, S., Witzenrath, M., Suttorp, N., Kurth, F., Franke, C., Endres, M., Schmitz, D., Jeworowski, L.M., Richter, A., Schmidt, M.L., Schwarz, T., Mueller, M.A., Drosten, C., Wendisch, D., Sander, L.E., Osterrieder, N., Wilson, I.A. and Pruess, H.
bioRxiv
: 2020.08.15.252320.
16 August 2020
A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model.
Kreye, J., Reincke, S.M., Kornau, H.C., Sánchez-Sendin, E., Corman, V.M., Liu, H., Yuan, M., Wu, N.C., Zhu, X., Lee, C.C.D., Trimpert, J., Höltje, M., Dietert, K., Stöffler, L., von Wardenburg, N., van Hoof, S., Homeyer, M.A., Hoffmann, J., Abdelgawad, A., Gruber, A.D., Bertzbach, L.D., Vladimirova, D., Li, L.Y., Barthel, P.C., Skriner, K., Hocke, A.C., Hippenstiel, S., Witzenrath, M., Suttorp, N., Kurth, F., Franke, C., Endres, M., Schmitz, D., Jeworowski, L.M., Richter, A., Schmidt, M.L., Schwarz, T., Müller, M.A., Drosten, C., Wendisch, D., Sander, L.E., Osterrieder, N., Wilson, I.A. and Prüss, H.
Cell 183
(4): 1058-1069.
12 November 2020
Artificial-intelligence-driven scanning probe microscopy.
Krull, A., Hirsch, P., Rother, C., Schiffrin, A. and Krull, C.
Communications Physics 3
(1): 54.
19 March 2020
Visualizing the central nervous system: imaging tools for multiple sclerosis and neuromyelitis optica spectrum disorders.
Kuchling, J. and Paul, F.
Frontiers in Neurology 11
: 450.
17 June 2020
Murine cytomegalovirus M25 proteins sequester the tumor suppressor protein p53 in nuclear accumulations.
Kutle, I., Szymańska-de Wijs, K.M., Bogdanow, B., Cuvalo, B., Steinbrück, L., Jonjić, S., Wagner, K., Niedenthal, R., Selbach, M., Wiebusch, L., Dezeljin, M. and Messerle, M.
Journal of Virology 94
(20): e00574-20.
October 2020
Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery.
Laidou, S., Alanis-Lobato, G., Pribyl, J., Raskó, T., Tichy, B., Mikulasek, K., Tsagiopoulou, M., Oppelt, J., Kastrinaki, G., Lefaki, M., Singh, M., Zink, A., Chondrogianni, N., Psomopoulos, F., Prigione, A., Ivics, Z., Pospisilova, S., Skladal, P., Izsvák, Z., Andrade-Navarro, M.A. and Petrakis, S.
Redox Biology 32
: 101458.
May 2020
Subcellular localization and formation of huntingtin aggregates correlates with symptom onset and progression in a Huntington's disease model.
Landles, C., Milton, R.E., Ali, N., Flomen, R., Flower, M., Schindler, F., Gomez-Paredes, C., Bondulich, M.K., Osborne, G.F., Goodwin, D., Salsbury, G., Benn, C.L., Sathasivam, K., Smith, E.J., Tabrizi, S.J., Wanker, E.E. and Bates, G.P.
Brain Communications 2
(2): fcaa066.
3 August 2020
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates.
Langer, H.T., Afzal, S., Kempa, S. and Spuler, S.
Scientific Reports 10
: 1908.
5 February 2020
Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer.
Le Poul, Y., Xin, Y., Ling, L., Mühling, B., Jaenichen, R., Hörl, D., Bunk, D., Harz, H., Leonhardt, H., Wang, Y., Osipova, E., Museridze, M., Dharmadhikari, D., Murphy, E., Rohs, R., Preibisch, S., Prud'homme, B. and Gompel, N.
Science Advances 6
(49): eabe2955.
2 December 2020
Deciphering the regulatory logic of a Drosophila enhancer through systematic sequence mutagenesis and quantitative image analysis.
Le Poul, Y., Xin, Y., Ling, L., Mühling, B., Jaenichen, R., Hörl, D., Bunk, D., Harz, H., Leonhardt, H., Wang, Y., Osipova, E., Museridze, M., Dharmadhikari, D., Murphy, E., Rohs, R., Preibisch, S., Prud'homme, B. and Gompel, N.
bioRxiv
: 2020.06.24.169748.
25 June 2020
William D. Willis, Jr, MD, PhD Memorial Lecture: the evolutionary history of nerve growth factor and nociception.
Lewin, G.R.
Pain 161
(9 Suppl 1): S36-S47.
September 2020
The predictive value of urinary kidney injury molecular 1 for the diagnosis of contrast-induced acute kidney injury after cardiac catheterization: a meta-analysis.
Li, Q., Huang, Y., Shang, W., Zhang, Y., Liu, Y. and Xu, G.
Journal of Interventional Cardiology 2020
: 4982987.
14 August 2020
Olig3 acts as a master regulator of cerebellar development.
Lowenstein, E.D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A.E., Epifanova, E., Bladt, F., Isik, E.G., Jia, S., Tarabykin, V. and Hernandez-Miranda, L.R.
bioRxiv
: 2020.10.10.334615.
10 October 2020
Fibroblasts from atopic dermatitis patients trigger inflammatory processes and hyperproliferation in human skin equivalents.
Löwa, A., Graff, P., Kaessmeyer, S. and Hedtrich, S.
Journal of the European Academy of Dermatology and Venereology 34
(6): e262-e265.
June 2020
PatchPerPix for instance segmentation.
Mais, L., Hirsch, P. and Kainmueller, D.
Lecture Notes in Computer Science 12370
: 288-304.
20 November 2020
MyoMiner: explore gene co-expression in normal and pathological muscle.
Malatras, A., Michalopoulos, I., Duguez, S., Butler-Browne, G., Spuler, S. and Duddy, W.J.
BMC Medical Genomics 13
(1): 67.
11 May 2020
Teriflunomide preserves peripheral nerve mitochondria from oxidative stress-mediated alterations.
Malla, B., Cotten, S., Ulshoefer, R., Paul, F., Hauser, A.E., Niesner, R., Bros, H. and Infante-Duarte, C.
Therapeutic Advances in Chronic Disease 11
: 1-14.
2020
EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C., Lahmann, I., Kunz, S., Jonas, W., Melo, A.A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Blüher, M., Olschowski, H., Kompa, J., Brügger, B., Müller, D.N., Haucke, V., Schürmann, A., Birchmeier, C. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 117
(13): 7471-7481.
31 March 2020
Tackling mitochondrial diversity in brain function: from animal models to human brain organoids.
Menacho, C. and Prigione, A.
International Journal of Biochemistry and Cell Biology 123
: 105760.
June 2020
Value of neuropsychological tests to identify patients with depressive symptoms on the Alzheimer's disease continuum.
Menne, F., Schipke, C.G., Klostermann, A., Fuentes-Casañ, M., Freiesleben, S.D., Bauer, C. and Peters, O.
Journal of Alzheimer's Disease 78
(2): 819-826.
10 November 2020
Generation of two human induced Pluripotent Stem Cell lines derived from myoblasts (MDCi014-A) and from peripheral blood mononuclear cells (MDCi014-B) from the same donor.
Metzler, E., Telugu, N., Diecke, S., Spuler, S. and Escobar, H.
Stem Cell Research 48
: 101998.
October 2020
Peptide-based interaction proteomics.
Meyer, K. and Selbach, M.
Molecular & Cellular Proteomics 19
(7): 1070-1075.
July 2020
Blunted neural and psychological stress processing predicts future grey matter atrophy in multiple sclerosis.
Meyer-Arndt, L., Hetzer, S., Asseyer, S., Bellmann-Strobl, J., Scheel, M., Stellmann, J.Pa., Heesen, C., Engel, A.K., Brandt, A.U., Haynes, J.D., Paul, F., Gold, S.M. and Weygandt, M.
Neurobiology of Stress 13
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November 2020
Spikelets in pyramidal neurons: generating mechanisms, distinguishing properties, and functional implications.
Michalikova, M., Remme, M.W.H., Schmitz, D., Schreiber, S. and Kempter, R.
Reviews in the Neurosciences 31
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January 2020
Transient enlargement of brain ventricles during relapsing-remitting multiple sclerosis and experimental autoimmune encephalomyelitis.
Millward, J.M., Delgado, P.R., Smorodchenko, A., Boehmert, L., Periquito, J., Reimann, H.M., Prinz, C., Els, A., Scheel, M., Bellmann-Strobl, J., Waiczies, H., Wuerfel, J., Infante-Duarte, C., Chien, C., Kuchling, J., Pohlmann, A., Zipp, F., Paul, F., Niendorf, T. and Waiczies, S.
JCI Insight 5
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5 November 2020
Circuit-specific dendritic development in the piriform cortex.
Moreno-Velasquez, L., Lo, H., Lenzi, S., Kaehne, M., Breustedt, J., Schmitz, D., Rüdiger, S. and Johenning, F.W.
eNeuro 7
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May 2020
Altered fovea in AQP4-IgG-seropositive neuromyelitis optica spectrum disorders.
Motamedi, S., Oertel, F.C., Yadav, S.K., Kadas, E.M., Weise, M., Havla, J., Ringelstein, M., Aktas, O., Albrecht, P., Ruprecht, K., Bellmann-Strobl, J., Zimmermann, H.G., Paul, F. and Brandt, A.U.
Neurology Neuroimmunology & Neuroinflammation 7
(5): e805.
September 2020
Epigenetic chaperoning of aging.
Müthel, S. and Tursun, B.
Aging 12
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31 January 2020
Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.
Nakamura, R., Numata, T., Kasuya, G., Yokoyama, T., Nishizawa, T., Kusakizako, T., Kato, T., Hagino, T., Dohmae, N., Inoue, M., Watanabe, K., Ichijo, H., Kikkawa, M., Shirouzu, M., Jentsch, T.J., Ishitani, R., Okada, Y. and Nureki, O.
Communications Biology 3
(1): 240.
15 May 2020
Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway.
Nitzan, N., McKenzie, S., Beed, P., English, D.F., Oldani, S., Tukker, J.J., Buzsáki, G. and Schmitz, D.
Nature Communications 11
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23 April 2020
Functionally relevant maculopathy and optic atrophy in spinocerebellar ataxia type 1.
Oertel, F.C., Zeitz, O., Rönnefarth, M., Bereuter, C., Motamedi, S., Zimmermann, H.G., Kuchling, J., Grosch, A.S., Doss, S., Browne, A., Paul, F., Schmitz-Hübsch, T. and Brandt, A.U.
Movement Disorders Clinical Practice 7
(5): 502-508.
July 2020
Increased and synchronous recruitment of release sites underlies hippocampal mossy fiber presynaptic potentiation.
Orlando, M., Dvorzhak, A., Bruentgens, F., Maglione, M., Rost, B.R., Sigrist, S.J., Breustedt, Jm and Schmitz, D.
bioRxiv
: 2020.08.21.260638.
21 August 2020
SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of MS patients.
Ostendorf, L., Dittert, P., Biesen, R., Duchow, A., Stiglbauer, V., Ruprecht, K., Seelow, D., Niesner, R.A., Hauser, A.E., Paul, F. and Radbruch, H.
medRxiv
: 2020.12.18.20248500.
22 December 2020
Instrumental assessment of stepping in place captures clinically relevant motor symptoms of Parkinson's disease.
Otte, K., Ellermeyer, T., Vater, T.S., Voigt, M., Kroneberg, D., Rasche, L., Krüger, T., Röhling, H.M., Kayser, B., Mansow-Model, S., Klostermann, F., Brandt, A.U., Paul, F., Lipp, A. and Schmitz-Hübsch, T.
Sensors 20
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1 October 2020
eATP/P2X7R axis: an orchestrated pathway triggering inflammasome activation in muscle diseases.
Panicucci, C., Raffaghello, L., Bruzzone, S., Baratto, S., Principi, E., Minetti, C., Gazzerro, E. and Bruno, C.
International Journal of Molecular Sciences 21
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19 August 2020
Dynamic conjugate F-SHARP microscopy.
Papadopoulos, I.N., Jouhanneau, J.S., Takahashi, N., Kaplan, D., Larkum, M., Poulet, J. and Judkewitz, B.
Light: Science & Applications 9
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30 June 2020
The sensory coding of warm perception.
Paricio-Montesinos, R., Schwaller, F., Udhayachandran, A., Rau, F., Walcher, J., Evangelista, R., Vriens, J., Voets, T., Poulet, J.F.A. and Lewin, G.R.
Neuron 106
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3 June 2020
TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.
Patkunarajah, A., Stear, J.H., Moroni, M., Schroeter, L., Blaszkiewicz, J., Tearle, J.L.E., Cox, C.D., Fuerst, C., Sánchez-Carranza, O., Ocaña Fernández, M.D.A., Fleischer, R., Eravci, M., Weise, C., Martinac, B., Biro, M., Lewin, G.R. and Poole, K.
eLife 9
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31 March 2020
Protein corona formation and its influence on biomimetic magnetite nanoparticles.
Peigneux, A., Glitscher, E.A., Charbaji, R., Weise, C., Wedepohl, S., Calderón, M., Jimenez-Lopez, C. and Hedtrich, S.
Journal of Materials Chemistry B 8
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14 June 2020
Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis.
Petrou, P., Kassis, I., Levin, N., Paul, F., Backner, Y., Benoliel, T., Oertel, F.C., Scheel, M., Hallimi, M., Yaghmour, N., Hur, T.B., Ginzberg, A., Levy, Y., Abramsky, O. and Karussis, D.
Brain 143
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December 2020
A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation.
Poh, J., Ponsford, A.H., Boyd, J., Woodsmith, J., Stelzl, U., Wanker, E., Harper, N., MacEwan, D. and Sanderson, C.M.
Redox Biology 37
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October 2020
A recurrent gain-of-function mutation in CLCN6, encoding the ClC-6 Cl-/H+-exchanger, causes early-onset neurodegeneration.
Polovitskaya, M.M., Barbini, C., Martinelli, D., Harms, F.L., Cole, F.S., Calligari, P., Bocchinfuso, G., Stella, L., Ciolfi, A., Niceta, M., Rizza, T., Shinawi, M., Sisco, K., Johannsen, J., Denecke, J., Carrozzo, R., Wegner, D.J., Kutsche, K., Tartaglia, M. and Jentsch, T.J.
American Journal of Human Genetics 107
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3 December 2020
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.
Quach, B.C., Bray, M.J., Gaddis, N.C., Liu, M., Palviainen, T., Minica, C.C., Zellers, S., Sherva, R., Aliev, F., Nothnagel, M., Young, K.A., Marks, J.A., Young, H., Carnes, M.U., Guo, Y., Waldrop, A., Sey, N..A., Landi, M.T., McNeil, D.W., Drichel, D., Farrer, L.A., Markunas, C.A., Vink, J.M., Hottenga, J.J., Iacono, W.G., Kranzler, H.R., Saccone, N.L., Neale, M.C., Madden, P., Rietschel, M., Marazita, M.L., McGue, M., Won, H., Winterer, G., Grucza, R., Dick, D.M., Gelernter, J., Caporaso, N.E., Baker, T.B., Boomsma, D.I., Kaprio, J., Hokanson, J.E., Vrieze, S., Bierut, L.J., Johnson, E.O. and Hancock, D.B.
Nature Communications 11
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3 November 2020
Studying human glial cells: where are we today?
Ransom, B.R. and Kettenmann, H.
Glia 68
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April 2020
Non-ionic PEG-oligoglycerol dendron conjugated nano-carriers for dermal drug delivery.
Rashmi, Zabihi, F., Singh, A.K., Achazi, K., Schade, B., Hedtrich, S., Haag, R. and Sharma, S.K.
International Journal of Pharmaceutics 580
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30 April 2020
The CAR group of Ig cell adhesion proteins - regulators of gap junctions?
Rathjen, F.G.
BioEssays 42
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December 2020
Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology.
Rieux, M., Alpaugh, M., Sciacca, G., Saint-Pierre, M., Masnata, M., Denis, H.L., Lévesque, S.A., Herrmann, F., Bazenet, C., Garneau, A.P., Isenring, P., Truant, R., Oueslati, A., Gould, P.V., Ast, A., Wanker, E.E., Lacroix, S. and Cicchetti, F.
Molecular Psychiatry 26
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September 2020
Longitudinal optic neuritis-unrelated visual evoked potential changes in NMO spectrum disorders.
Ringelstein, M., Harmel, J., Zimmermann, H., Brandt, A.U., Paul, F., Haarmann, A., Buttmann, M., Hümmert, M.W., Trebst, C., Schroeder, C., Ayzenberg, I., Kleiter, I., Hellwig, K., Havla, J., Kümpfel, T., Jarius, S., Wildemann, B., Rommer, P., Weber, M.S., Pellkofer, H., Röpke, L., Geis, C., Retzlaff, N., Zettl, U., Deppe, M., Klotz, L., Young, K., Stellmann, J.P., Kaste, M., Kermer, P., Marouf, W., Lauda, F., Tumani, H., Graf, J., Klistorner, A., Hartung, H.P., Aktas, O. and Albrecht, P.
Neurology 94
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28 January 2020
A CRISPR-Cas9-engineered mouse model for GPI anchor deficiency mirrors human phenotype and shows hippocampal synaptic dysfunctions.
Rodríguez de los Santos, M., Rivalan, M., David, F.S., Knaus, A., Stumpf, A., Velasquez, L.M., Voigt, A., Mattei, D., Long, M., Vogt, G., Wittler, L., Timmermann, B., Robinson, P.N., Horn, D., Mundlos, S., Kornak, U., Schmitz, D., Winter, Y. and Krawitz, P.M.
bioRxiv
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21 April 2020
Neuroinflammatory alterations in trait anxiety: modulatory effects of minocycline.
Rooney, S., Sah, A., Unger, M.S., Kharitonova, M., Sartori, S.B., Schwarzer, C., Aigner, L., Kettenmann, H., Wolf, S.A. and Singewald, N.
Translational Psychiatry 10
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30 July 2020
Comparison of RNA isolation procedures for analysis of adult murine brain and spinal cord astrocytes.
Rosiewicz, K.S., Crowley, T., Saher, G., Kerkering, J., Alisch, M. and Siffrin, V.
Journal of Neuroscience Methods 333
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1 March 2020
Dysphagia affecting quality of life in cerebellar ataxia - a large survey.
Rönnefarth, M., Hanisch, N., Brandt, A.U., Mähler, A., Endres, M., Paul, F. and Doss, S.
Cerebellum 19
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June 2020
Chloride transport across the lysosomal membrane.
Saha, S., Blessing, A. and Jentsch, T.J.
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CRC Press, Boca Raton, 19-44.
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2020
Local microcircuitry of parasubiculum shows distinct and common features of excitatory and inhibitory connectivity.
Sammons, R.P., Tzilivaki, A. and Schmitz, D.
bioRxiv
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19 December 2020
An international standardized magnetic resonance imaging protocol for diagnosis and follow-up of patients with multiple sclerosis.
Saslow, L., Li, D.K.B., Halper, J., Banwell, B., Barkhof, F., Barlow, L., Costello, K., Damiri, P., Dunn, J., Giri, S., Maes, M., Morrow, S.A., Newsome, S.D., Oh, J., Paul, F., Quarterman, P., Reich, D.S., Shewchuk, J.R., Shinohara, R.T., Van Hecke, W., van de Ven, K., Wallin, M.T., Wolinsky, J.S. and Traboulsee, A.
International Journal of MS Care 22
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27 October 2020
A connectome and analysis of the adult Drosophila central brain.
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eLife 9
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7 September 2020
Differences in advanced magnetic resonance imaging in MOG-IgG and AQP4-IgG seropositive neuromyelitis optica spectrum disorders: a comparative study.
Schmidt, F.A., Chien, C., Kuchling, J., Bellmann-Strobl, J., Ruprecht, K., Siebert, N., Asseyer, S., Jarius, S., Brandt, A.U., Scheel, M. and Paul, F.
Frontiers in Neurology 11
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30 September 2020
Neutrophil gelatinase-associated lipocalin protects from ANCA-induced GN by inhibiting T(H)17 immunity.
Schreiber, A., Rousselle, A., Klocke, J., Bachmann, S., Popovic, S., Bontscho, J., Schmidt-Ott, K.M., Siffrin, V., Jerke, U., Ashraf, M.I., Panzer, U. and Kettritz, R.
Journal of the American Society of Nephrology 31
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July 2020
Collagen organization within the cartilage of TRPV4(-/-) mice studied with two-photon microscopy and polarized second harmonic generation.
Servin-Vences, M.R., Poole, K., Sporbert, A., Lewin, G.R. and Margineanu, A.
Cytometry Part A 97
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May 2020
Nonclinical data supporting orphan medicinal product designations in the area of rare infectious diseases.
Sheean, M.E., Malikova, E., Duarte, D., Capovilla, G., Fregonese, L., Hofer, M., Magrelli, A., Mariz, S., Mendez-Hermida, F., Nistico, R., Leest, T., Sipsas, N.V., Tsigkos, S., Vitezic, D., Larsson, K., Sepodes, B. and Stoyanova-Beninska, V.
Drug Discovery Today 25
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February 2020
Tumour-derived CSF2/granulocyte macrophage colony stimulating factor controls myeloid cell accumulation and progression of gliomas.
Sielska, M., Przanowski, P., Pasierbińska, M., Wojnicki, K., Poleszak, K., Wojtas, B., Grzeganek, D., Ellert-Miklaszewska, A., Ku, M.C., Kettenmann, H. and Kaminska, B.
British Journal of Cancer 123
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4 August 2020
The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay.
Silla, T., Schmid, M., Dou, Y., Garland, W., Milek, M., Imami, K., Johnsen, D., Polak, P., Andersen, J.S., Selbach, M., Landthaler, M. and Jensen, T.
Nucleic Acids Research 48
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18 March 2020
Afadin signaling at the spinal neuroepithelium regulates central canal formation and gait selection.
Skarlatou, S., Hérent, C., Toscano, E., Mendes, C.S., Bouvier, J. and Zampieri, N.
Cell Reports 31
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9 June 2020
Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms.
Smith, E.S.J., Park, T.J. and Lewin, G.R.
Journal of Comparative Physiology A 206
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May 2020
Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders (CROCTINO).
Specovius, S., Zimmermann, H.G., Oertel, F.C., Chien, C., Bereuter, C., Cook, L.J., Lana Peixoto, M.A., Fontenelle, M.A., Kim, H.J., Hyun, J.W., Jung, S.K., Palace, J., Roca-Fernandez, A., Diaz, A.R., Leite, M.I., Sharma, S.M., Ashtari, F., Kafieh, R., Dehghani, A., Pourazizi, M., Pandit, L., Dcunha, A., Aktas, O., Ringelstein, M., Albrecht, P., May, E., Tongco, C., Leocani, L., Pisa, M., Radaelli, M., Martinez-Lapiscina, E.H., Stiebel-Kalish, H., Hellmann, M., Lotan, I., Siritho, S., de Seze, J., Senger, T., Havla, J., Marignier, R., Tilikete, C., Cobo Calvo, A., Bichuetti, D.B., Tavares, I.M., Asgari, N., Soelberg, K., Altintas, A., Yildirim, R., Tanriverdi, U., Jacob, A., Huda, S., Rimler, Z., Reid, A., Mao-Draayer, Y., de Castillo, I.S., Yeaman, M.R., Smith, T.J., Brandt, A.U. and Paul, F.
BMJ Open 10
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29 October 2020
Attenuated epigenetic suppression of muscle stem cell necroptosis is required for efficient regeneration of dystrophic muscles.
Sreenivasan, K., Ianni, A., Künne, C., Strilic, B., Günther, S., Perdiguero, E., Krüger, M., Spuler, S., Offermanns, S., Gómez-Del Arco, P., Redondo, J.M., Munoz-Canoves, P., Kim, J. and Braun, T.
Cell Reports 31
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19 May 2020
Antibody signatures in patients with histopathologically defined multiple sclerosis patterns.
Stork, L., Ellenberger, D., Ruprecht, K., Reindl, M., Beißbarth, T., Friede, T., Kümpfel, T., Gerdes, L.A., Gloth, M., Liman, T., Paul, F., Brück, W. and Metz, I.
Acta Neuropathologica 139
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March 2020
Lipid mediator profiles predict response to therapy with an oral frankincense extract in relapsing-remitting multiple sclerosis.
Stürner, K.H., Werz, O., Koeberle, A., Otto, M., Pless, O., Leypoldt, F., Paul, F. and Heesen, C.
Scientific Reports 10
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29 May 2020
N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation.
Sy, M., Brandt, A.U., Lee, S.U., Newton, B. L., Pawling, J., Golzar, A., Rahman, A.A., Yu, Z., Cooper, G., Scheel, M., Paul, F., Dennis, J.W. and Demetriou, M.
Journal of Biological Chemistry 295
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18 December 2020
Keeping the proportions of protein complex components in check.
Taggart, J.C., Zauber, H., Selbach, M., Li, G.W. and McShane, E.
Cell Systems 10
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26 February 2020
Phosphosite analysis of the cytomegaloviral mRNA export factor pUL69 reveals serines with critical importance for recruitment of cellular proteins Pin1 and UAP56/URH49.
Thomas, M., Müller, R., Horn, G., Bogdanow, B., Imami, K., Milbradt, J., Steingruber, M., Marschall, M., Schilling, E.M., Fossen, T. and Stamminger, T.
Journal of Virology 94
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31 March 2020
New algorithms improving PML risk stratification in MS patients treated with natalizumab.
Toboso, I., Tejeda-Velarde, A., Alvarez-Lafuente, R., Arroyo, R., Hegen, H., Deisenhammer, F., Sainz de la Maza, S., Alvarez-Cermeño, J.C., Izquierdo, G., Paramo, D., Oliva, P., Casanova, B., Agüera-Morales, E., Franciotta, D., Gastaldi, M., Fernández, O., Urbaneja, P., Garcia-Dominguez, J.M., Romero, F., Laroni, A., Uccelli, A., Perez-Sempere, A., Saiz, A., Blanco, Y., Galimberti, D., Scarpini, E., Espejo, C., Montalban, X., Rasche, L., Paul, F., González, I., Álvarez, E., Ramo, C., Caminero, A.B., Aladro, Y., Calles, C., Eguía, P., Belenguer-Benavides, A., Ramió-Torrentà, L., Quintana, E., Martínez-Rodríguez, J.E., Oterino, A., López de Silanes, C., Casanova, L.I., Landete, L., Frederiksen, J., Bsteh, G., Mulero, P., Comabella, M., Hernández, M.A., Espiño, M., Prieto, J.M., Pérez, D., Otano, M., Padilla, F., García-Merino, J.A., Navarro, L., Muriel, A., Frossard, L.C. and Villar, L.M.
Frontiers in Neurology 11
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17 December 2020
Could electrical coupling contribute to the formation of cell assemblies?
Traub, R.D., Whittington, M.A., Maier, N., Schmitz, D. and Nagy, J.I.
Reviews in the Neurosciences 31
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February 2020
O-Vanillin attenuates the TLR2 mediated tumor-promoting phenotype of microglia.
Triller, P., Bachorz, J., Synowitz, M., Kettenmann, H. and Markovic, D.
International Journal of Molecular Sciences 21
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22 April 2020
Up and down states and memory consolidation across somatosensory, entorhinal, and hippocampal cortices.
Tukker, J.J., Beed, P., Schmitz, D., Larkum, M.E. and Sachdev, R.N.S.
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8 May 2020
Cl(-) channels and Cl(-)/H(+) exchangers.
Ullrich, F. and Jentsch, T.J.
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Springer, Cham, 1-8.
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Phrenic-specific transcriptional programs shape respiratory motor output.
Vagnozzi, A.N., Garg, K., Dewitz, C., Moore, M.T., Cregg, J.M., Jeannotte, L., Zampieri, N., Landmesser, L.T. and Philippidou, P.
eLife 9
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16 January 2020
SynergyNet: a fusion framework for multiple sclerosis brain MRI segmentation with local refinement.
Vang, Y.S., Cao, Y., Chang, P.D., Chow, D.S., Brandt, A.U., Paul, F., Scheel, M. and Xie, X.
In: 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), 3-7 Apr 2020, Iowa City, IA, USA.
22 May 2020
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites.
Veenvliet, J.V., Bolondi, A., Kretzmer, H., Haut, L., Scholze-Wittler, M., Schifferl, D., Koch, F., Guignard, L., Kumar, A.S., Pustet, M., Heimann, S., Buschow, R., Wittler, L., Timmermann, B., Meissner, A. and Herrmann, B.G.
Science 370
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11 December 2020
Megadalton-sized dityrosine aggregates of α-synuclein retain high degrees of structural disorder and internal dynamics.
Verzini, S., Shah, M., Theillet, F.X., Belsom, A., Bieschke, J., Wanker, E.E., Rappsilber, J., Binolfi, A. and Selenko, P.
Journal of Molecular Biology 432
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4 December 2020
Sex differences in brain atrophy in multiple sclerosis.
Voskuhl, R.R., Patel, K., Paul, F., Gold, S.M., Scheel, M., Kuchling, J., Cooper, G., Asseyer, S., Chien, C., Brandt, A.U., Meyer, C.E. and MacKenzie-Graham, A.
Biology of Sex Differences 11
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28 August 2020
Altered coupling of psychological relaxation and regional volume of brain reward areas in multiple sclerosis.
Wakonig, K., Eitel, F., Ritter, K., Hetzer, S., Schmitz-Hübsch, T., Bellmann-Strobl, J., Haynes, J.D., Brandt, A.U., Gold, S.M., Paul, F. and Weygandt, M.
Frontiers in Neurology 11
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6 October 2020
Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.
Weinert, S., Gimber, N., Deuschel, D., Stuhlmann, T., Puchkov, D., Farsi, Z., Ludwig, C.F., Novarino, G., López-Cayuqueo, K.I., Planells-Cases, R. and Jentsch, T.J.
EMBO Journal 39
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4 May 2020
Treatment of MOG-IgG-associated disorder with rituximab: an international study of 121 patients.
Whittam, D.H., Cobo-Calvo, A., Lopez-Chiriboga, A.S., Pardo, S., Gornall, M., Cicconi, S., Brandt, A., Berek, K., Berger, T., Jelcic, I., Gombolay, G., Oliveira, L.M., Callegaro, D., Kaneko, K., Misu, T., Capobianco, M., Gibbons, E., Karthikeayan, V., Brochet, B., Audoin, B., Mathey, G., Laplaud, D., Thouvenot, E., Cohen, M., Tourbah, A., Maillart, E., Ciron, J., Deschamps, R., Biotti, D., Rostasy, K., Neuteboom, R., Hemingway, C., Forsyth, R., Matiello, M., Webb, S., Hunt, D., Murray, K., Hacohen, Y., Lim, M., Leite, M.I., Palace, J., Solomon, T., Lutterotti, A., Fujihara, K., Nakashima, I., Bennett, J.L., Pandit, L., Chitnis, T., Weinshenker, B.G., Wildemann, B., Sato, D.K., Kim, S.H., Huda, S., Kim, H.J., Reindl, M., Levy, M., Jarius, S., Tenembaum, S., Paul, F., Pittock, S., Marignier, R. and Jacob, A.
Multiple Sclerosis and Related Disorders 44
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September 2020
Treatment of MOG antibody associated disorders: results of an international survey.
Whittam, D.H., Karthikeayan, V., Gibbons, E., Kneen, R., Chandratre, S., Ciccarelli, O., Hacohen, Y., de Seze, J., Deiva, K., Hintzen, R.Q., Wildemann, B., Jarius, S., Kleiter, I., Rostasy, K., Huppke, P., Hemmer, B., Paul, F., Aktas, O., Pröbstel, A.K., Arrambide, G., Tintore, M., Amato, M.P., Nosadini, M., Mancardi, M.M., Capobianco, M., Illes, Z., Siva, A., Altintas, A., Akman-Demir, G., Pandit, L., Apiwattankul, M., Hor, J.Y., Viswanathan, S., Qiu, W., Kim, H.J., Nakashima, I., Fujihara, K., Ramanathan, S., Dale, R.C., Boggild, M., Broadley, S., Lana-Peixoto, M.A., Sato, D.K., Tenembaum, S., Cabre, P., Wingerchuk, D.M., Weinshenker, B.G., Greenberg, B., Matiello, M., Klawiter, E.C., Bennett, J.L., Wallach, A.I., Kister, I., Banwell, B.L., Traboulsee, A., Pohl, D., Palace, J., Leite, M.I., Levy, M., Marignier, R., Solomon, T., Lim, M., Huda, S. and Jacob, A.
Journal of Neurology 367
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December 2020
Sclerotiorin stabilizes the assembly of nonfibrillar Abeta42 oligomers with low toxicity, seeding activity, and beta-sheet content.
Wiglenda, T., Groenke, N., Hoffmann, W., Manz, C., Diez, L., Buntru, A., Brusendorf, L., Neuendorf, N., Schnoegl, S., Haenig, C., Schmieder, P., Pagel, K. and Wanker, E.E.
Journal of Molecular Biology 432
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27 March 2020
SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis.
Wurmser, M., Chaverot, N., Madani, R., Sakai, H., Negroni, E., Demignon, J., Saint-Pierre, B., Mouly, V., Amthor, H., Tapscott, S., Birchmeier, C., Tajbakhsh, S., Le Grand, F., Sotiropoulos, A. and Maire, P.
Development 147
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9 October 2020
Identification of glioma cancer stem cell characteristics based on weighted gene prognosis module co-expression network analysis of transcriptome data stemness indices.
Xia, P., Li, Q., Wu, G. and Huang, Y.
Journal of Molecular Neuroscience 70
(10): 1512-1520.
October 2020
Ketamine effects on default mode network activity and vigilance: a randomized, placebo-controlled crossover simultaneous fMRI/EEG study.
Zacharias, N., Musso, F., Müller, F., Lammers, F., Saleh, A., London, M., de Boer, P. and Winterer, G.
Human Brain Mapping 41
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January 2020
Transfer of cGAMP into bystander cells via LRRC8 volume-regulated anion channels augments STING-mediated interferon responses and anti-viral immunity.
Zhou, C., Chen, X., Planells-Cases, R., Chu, J., Wang, L., Cao, L., Li, Z., López-Cayuqueo, K.I., Xie, Y., Ye, S., Wang, X., Ullrich, F., Ma, S., Fang, Y., Zhang, X., Qian, Z., Liang, X., Cai, S.Q., Jiang, Z., Zhou, D., Leng, Q., Xiao, T.S., Lan, K., Yang, Ji., Li, H., Peng, C., Qiu, Z., Jentsch, T.J. and Xiao, H.
Immunity 52
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19 May 2020
Understanding neurodegenerative changes of the afferent visual pathway in MS.
Zimmermann, H.G. and Oertel, F.C.
Neurology Neuroimmunology & Neuroinflammation 7
(2): e667.
March 2020
Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay.
Zink, A., Conrad, J., Telugu, N.S., Diecke, S., Heinz, A., Wanker, E., Priller, J. and Prigione, A.
Frontiers in Cell and Developmental Biology 8
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5 November 2020
Serotonin suppresses slow oscillations by activating somatostatin interneurons via the 5-HT(2A) receptor.
de Filippo, R., Rost, B., Stumpf, A., Cooper, C., Tukker, J.J., Harms, C., Beed, P. and Schmitz, D.
bioRxiv
: 2020.05.26.113373.
26 May 2020
Conversion of germ cells to somatic cell types in C. elegans.
ul Fatima, N. and Tursun, B.
Journal of Developmental Biology 8
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December 2020
Conservation of a core neurite transcriptome across neuronal types and species.
von Kügelgen, N. and Chekulaeva, M.
Wiley Interdisciplinary Reviews: RNA 11
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July 2020
2019
A novel non-invasive method to detect RELM beta transcript in gut barrier related changes during a gastrointestinal nematode infection.
Ahmed, N., Heitlinger, E., Affinass, N., Kühl, A.A., Xenophontos, N., Jarquin, V.H., Jost, J., Steinfelder, S. and Hartmann, S.
Frontiers in Immunology 10
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March 2019
Quantification and characterization of radical production in human, animal and 3D skin models during sun irradiation measured by EPR spectroscopy.
Albrecht, S., Elpelt, A., Kasim, C., Reble, C., Mundhenk, L., Pischon, H., Hedtrich, S., Witzel, C., Lademann, J., Zastrow, L., Beckers, I. and Meinke, M.C.
Free Radical Biology and Medicine 131
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1 February 2019
Vision and vision-related measures in progressive multiple sclerosis.
Backner, Y., Petrou, P., Glick-Shames, H., Raz, N., Zimmermann, H., Jost, R., Scheel, M., Paul, F., Karussis, D. and Levin, N.
Frontiers in Neurology 10
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May 2019
Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study.
Balk, L.J., Coric, D., Knier, B., Zimmermann, H.G., Behbehani, R., Alroughani, R., Martinez-Lapiscina, E.H., Brandt, A.U., Sánchez-Dalmau, B., Vidal-Jordana, A., Albrecht, P., Koska, V., Havla, J., Pisa, M., Nolan, R.C., Leocani, L., Paul, F., Aktas, O., Montalban, X., Balcer, L.J., Villoslada, P., Outteryck, O., Korn, T. and Petzold, A.
Multiple Sclerosis Journal Experimental Translational and Clinical 5
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1 July 2019
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembling cofactors ASPL/PUX1.
Banchenko, S., Arumughan, A., Petrović, S., Schwefel, D., Wanker, E.E., Roske, Y. and Heinemann, U.
Structure 27
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3 December 2019
Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein.
Birol, M., Wojcik, S.P., Miranker, A.D. and Rhoades, E.
PLoS Biology 17
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18 June 2019
Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose : aktueller Stand und Empfehlungen in Deutschland [Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : current status and recommendations in Germany].
Bittner, S., Engel, S., Lange, C., Weber, M.S., Haghikia, A., Luessi, F., Korn, T., Klotz, L., Bayas, A., Paul, F., Heesen, C., Stangel, M., Wildemann, B., Bergh, F.T., Tackenberg, B., Trebst, C., Warnke, C., Linker, R., Kerschensteiner, M., Zettl, U., Tumani, H., Brück, W., Meuth, S.G., Kümpfel, T., Hemmer, B., Wiendl, H., Gold, R. and Zipp, F.
Nervenarzt 90
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December 2019
Subclinical myocardial injury in patients with Facioscapulohumeral muscular dystrophy 1 and preserved ejection fraction - assessment by cardiovascular magnetic resonance.
Blaszczyk, E., Grieben, U., von Knobelsdorff-Brenkenhoff, F., Kellman, P., Schmacht, L., Funk, S., Spuler, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 21
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29 April 2019
The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A., Babila, J.T., Wiglenda, T., Diez, L., Jacob, M., Nietfeld, W., Huska, M.R., Haenig, C., Groenke, N., Buntru, A., Blanc, E., Meier, J.C., Vannoni, E., Erck, C., Friedrich, B., Martens, H., Neuendorf, N., Schnoegl, S., Wolfer, D.P., Loos, M., Beule, D., Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26
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17 January 2019
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B., Wang, X., Eichelbaum, K., Sadewasser, A., Husic, I., Paki, K., Budt, M., Hergeselle, M., Vetter, B., Hou, J., Chen, W., Wiebusch, L., Meyer, I.M., Wolff, T. and Selbach, M.
Nature Communications 10
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4 December 2019
Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage.
Boltze, J., Ferrara, F., Hainsworth, A.H., Bridges, L.R., Zille, M., Lobsien, D., Barthel, H., McLeod, D.D., Gräßer, F., Pietsch, S., Schatzl, A.K., Dreyer, A.Y. and Nitzsche, B.
Journal of Cerebral Blood Flow and Metabolism 39
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1 December 2019
Somatostatin 2 receptors in the spinal cord tonically restrain thermogenic, cardiac and other sympathetic outflows.
Bowman, B.R., Bokiniec, P., McMullan, S., Goodchild, A.K. and Burke, P.G.R.
Frontiers in Neuroscience 13
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February 2019
Light-microscopy methods in C. elegans research.
Breimann, L., Preusser, F. and Preibisch, S.
Current Opinion in Systems Biology 13
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February 2019
RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses.
Brockmann, M.M., Maglione, M., Willmes, C.G., Stumpf, A., Bouazza, B.A., Velasquez, L.M., Grauel, M.K., Beed, P., Lehmann, M., Gimber, N., Schmoranzer, J., Sigrist, S.J., Rosenmund, C. and Schmitz, D.
eLife 8
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19 September 2019
let-7 microRNAs regulate microglial function and suppress glioma growth through Toll-like receptor 7.
Buonfiglioli, A., Efe, I.E., Guneykaya, D., Ivanov, A., Huang, Y., Orlowski, E., Krüger, C., Deisz, R.A., Markovic, D., Flüh, C., Newman, A.G., Schneider, U.C., Beule, D., Wolf, S.A., Dzaye, O., Gutmann, D.H., Semtner, M., Kettenmann, H. and Lehnardt, S.
Cell Reports 29
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10 December 2019
Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis.
Böttcher, C., Fernández-Zapata, C., Schlickeiser, S., Kunkel, D., Schulz, A.R., Mei, H.E., Weidinger, C., Gieß, R.M., Asseyer, S., Siegmund, B., Paul, F., Ruprecht, K. and Priller, J.
Scientific Reports 9
(1): 19471.
19 December 2019
Postnatal Tshz3 deletion drives altered corticostriatal function and autism spectrum disorder-like behavior.
Chabbert, D., Caubit, X., Roubertoux, P.L., Carlier, M., Habermann, B., Jacq, B., Salin, P., Metwaly, M., Frahm, C., Fatmi, A., Garratt, A.N., Severac, D., Dubois, E., Kerkerian-Le Goff, L., Fasano, L. and Gubellini, P.
Biological Psychiatry 86
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15 August 2019
Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.
Chaimowicz, C., Ruffault, P.L., Chéret, C., Woehler, A., Zampieri, N., Fortin, G., Garratt, A.N. and Birchmeier, C.
Development 146
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6 September 2019
A cellular mechanism underlying enhanced capability for complex olfactory discrimination learning.
Chandra, N., Awasthi, R., Ozdogan, T., Johenning, F.W., Imbrosci, B., Morris, G., Schmitz, D. and Barkai, E.
eNeuro 6
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January 2019
Roles of long noncoding RNAs and circular RNAs in translation.
Chekulaeva, M. and Rajewsky, N.
Cold Spring Harbor Perspectives in Biology 11
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3 June 2019
Imaging markers of disability in aquaporin-4 immunoglobulin G seropositive neuromyelitis optica: a graph theory study.
Chien, C., Oertel, F.C., Siebert, N., Zimmermann, H., Asseyer, S., Kuchling, J., Scheel, M., Ruprecht, K., Bellmann-Strobl, J., Paul, F. and Brandt, A.U.
Brain Communications 1
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16 October 2019
Spinal cord lesions and atrophy in NMOSD with AQP4-IgG and MOG-IgG associated autoimmunity.
Chien, C., Scheel, M., Schmitz-Hübsch, T., Borisow, N., Ruprecht, K., Bellmann-Strobl, J., Paul, F. and Brandt, A.U.
Multiple Sclerosis Journal 25
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December 2019
Maximizing binary interactome mapping with a minimal number of assays.
Choi, S.G., Olivet, J., Cassonnet, P., Vidalain, P.O., Luck, K., Lambourne, L., Spirohn, K., Lemmens, I., Dos Santos, M., Demeret, C., Jones, L., Rangarajan, S., Bian, W., Coutant, E.P., Janin, Y.L., van der Werf, S., Trepte, P., Wanker, E.E., De Las Rivas, J., Tavernier, J., Twizere, J.C., Hao, T., Hill, D.E., Vidal, M., Calderwood, M.A. and Jacob, Y.
Nature Communications 10
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29 August 2019
Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders.
Ciccarelli, O., Cohen, J.A., Reingold, S.C. and Weinshenker, B.G.
Lancet Neurology 18
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February 2019
Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C., Rom, A., Franke, V., Imami, K., Arrey, G., Terne, M., Woehler, A., Akalin, A., Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47
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18 March 2019
Estrus-cycle regulation of cortical inhibition.
Clemens, A.M., Lenschow, C., Beed, P., Li, L., Sammons, R., Naumann, R.K., Wang, H., Schmitz, D. and Brecht, M.
Current Biology 29
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18 February 2019
Collaborative International Research in Clinical and Longitudinal Experience Study in NMOSD.
Cook, L.J., Rose, J.W., Alvey, J.S., Jolley, A.M., Kuhn, R., Marron, B., Pederson, M., Enriquez, R., Yearley, J., McKechnie, S., Han, M.H., Tomczak, A.J., Levy, M., Mealy, M.A., Coleman, J., Bennett, J.L., Johnson, R., Barnes-Garcia, M., Traboulsee, A.L., Carruthers, R.L., Lee, L.E., Schubert, J.J., McMullen, K., Kister, I., Rimler, Z., Reid, A., Sicotte, N.L., Planchon, S.M., Cohen, J.A., Ivancic, D., Sedlak, J.L., Sand, I.K., Repovic, P., Amezcua, L., Pruitt, A., Amundson, E., Chitnis, T., Mullin, D.S., Klawiter, E.C., Russo, A.W., Riley, C.S., Onomichi, K.B., Levine, L., Nelson, K.E., Nealon, N.M., Engel, C., Kruse-Hoyer, M., Marcille, M., Tornes, L., Rumpf, A., Greer, A., Kenneally Behne, M., Rodriguez, R.R., Behne, D.W., Blackway, D.W., Coords, B., Blaschke, T.F., Sheard, J., Smith, T.J., Behne, J.M. and Yeaman, M.R.
Neurology Neuroimmunology & Neuroinflammation 6
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September 2019
Standardization of T1w/T2w ratio improves detection of tissue damage in multiple sclerosis.
Cooper, G., Finke, C., Chien, C., Brandt, A.U., Asseyer, S., Ruprecht, K., Bellmann-Strobl, J., Paul, F. and Scheel, M.
Frontiers in Neurology 10
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April 2019
Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial.
Cree, B.A.C., Bennett, J.L., Kim, H.J., Weinshenker, B.G., Pittock, S.J., Wingerchuk, D.M., Fujihara, K., Paul, F., Cutter, G.R., Marignier, R., Green, A.J., Aktas, O., Hartung, H.P., Lublin, F.D., Drappa, J., Barron, G., Madani, S., Ratchford, J.N., She, D., Cimbora, D. and Katz, E.
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12 October 2019
Wnt11/Fzd7 signaling compartmentalizes AKAP2/PKA to regulate L-type Ca(2+) channel.
Csalyi, K.D., Rharass, T., Schulz, M., Phan, M.H.Q., Wakula, P., Mhatre, K.N., Plotnick, D., Werdich, A.A., Zauber, H., Sury, M.D., Selbach, M., Heinzel, F.R., Klussmann, E. and Panakova, D.
bioRxiv
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20 August 2019
N2 year in review and message from the editor to our reviewers.
Dalmau, J., Kolson, D.L., Paul, F. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 6
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January 2019
Organization of motor pools depends on the combined function of N-cadherin and type II cadherins.
Dewitz, C., Duan, X. and Zampieri, N.
Development 146
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10 July 2019
β-secretase BACE1 is required for normal cochlear function.
Dierich, M., Hartmann, S., Dietrich, N., Moeser, P., Brede, F., Johnson Chacko, L., Tziridis, K., Schilling, A., Krauss, P., Hessler, S., Karch, S., Schrott-Fischer, A., Blumer, M., Birchmeier, C., Oliver, D., Moser, T., Schulze, H., Alzheimer, C., Leitner, M.G. and Huth, T.
Journal of Neuroscience 39
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6 November 2019
Caenorhabditis elegans and systems biology - it is 'systems' all the way down!
Dupuy, D. and Tursun, B.
Current Opinion in Systems Biology 13
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February 2019
The choice of embedding media affects image quality, tissue R(2)*, and susceptibility behaviors in post‐mortem brain MR microscopy at 7.0T.
Dusek, P., Madai, V.I., Huelnhagen, T., Bahn, E., Matej, R., Sobesky, J., Niendorf, T., Acosta-Cabronero, Julio and Wuerfel, J.
Magnetic Resonance in Medicine 81
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April 2019
Single synapse indicators of impaired glutamate clearance derived from fast iGlu(u) imaging of cortical afferents in the striatum of normal and Huntington (Q175) mice.
Dvorzhak, A., Helassa, N., Török, K., Schmitz, D. and Grantyn, R.
Journal of Neuroscience 39
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15 May 2019
Rapid molecular evolution of pain insensitivity in multiple African rodents.
Eigenbrod, O., Debus, K.Y., Reznick, J., Bennett, N.C., Sánchez-Carranza, O., Omerbašić, D., Hart, D.W., Barker, A.J., Zhong, W., Lutermann, H., Katandukila, J.V., Mgode, G., Park, T.J. and Lewin, G.R.
Science 364
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31 May 2019
Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation.
Eitel, F., Soehler, E., Bellmann-Strobl, J., Brandt, A.U., Ruprecht, K., Giess, R.M., Kuchling, J., Asseyer, S., Weygandt, M., Haynes, J.D., Scheel, M., Paul, F. and Ritter, K.
NeuroImage: Clinical 24
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6 September 2019
Gadolinium in human brain sections and colocalization with other elements.
El-Khatib, A.H., Radbruch, H., Trog, S., Neumann, B., Paul, F., Koch, A., Linscheid, M.W., Jakubowski, N. and Schellenberger, E.
Neurology Neuroimmunology & Neuroinflammation 6
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January 2019
Insight into the redox status of inflammatory skin equivalents as determined by EPR spectroscopy.
Elpelt, A., Albrecht, S., Teutloff, C., Hüging, M., Saeidpour, S., Lohan, S.B., Hedtrich, S. and Meinke, M.C.
Chemico-Biological Interactions 310
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1 September 2019
On the presence and functional significance of sympathetic premotor neurons with collateralized spinal axons in the rat.
Farmer, D.G.S., Pracejus, N., Dempsey, B., Turner, A., Bokiniec, P., Paton, J.F.R., Pickering, A.E., Burguet, J., Andrey, P., Goodchild, A.K., McAllen, R.M. and McMullan, S.
Journal of Physiology 597
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1 July 2019
Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
Filippi, M., Preziosa, P., Banwell, B.L., Barkhof, F., Ciccarelli, O., De Stefano, N., Geurts, J.J.G., Paul, F., Reich, D.S., Toosy, A.T., Traboulsee, A., Wattjes, M.P., Yousry, T.A., Gass, A., Lubetzki, C., Weinshenker, B.G. and Rocca, M.A.
Brain 142
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July 2019
Stochastic transcription in the p53-mediated response to DNA damage is modulated by burst frequency.
Friedrich, D., Friedel, L., Finzel, A., Herrmann, A., Preibisch, S. and Loewer, A.
Molecular Systems Biology 15
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1 December 2019
A benchmark for epithelial cell tracking.
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23 January 2019
Supramolecular nanogels fabricated via host-guest molecular recognition as penetration enhancer for dermal drug delivery.
Gao, L., Zabihi, F., Ehrmann, S., Hedtrich, S. and Haag, R.
Journal of Controlled Release 300
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28 April 2019
Association of intrathecal immunoglobulin G synthesis with disability worsening in multiple sclerosis.
Gasperi, C., Salmen, A., Antony, G., Bayas, A., Heesen, C., Kümpfel, T., Linker, R.A., Paul, F., Stangel, M., Tackenberg, B., Bergh, F.T., Warnke, C., Weber, F., Wiendl, H., Wildemann, B., Zettl, U.K., Ziemann, U., Zipp, F., Tumani, H., Gold, R. and Hemmer, B.
JAMA Neurology 76
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29 April 2019
The danger signal extracellular ATP is involved in the immunomediated damage of α-sarcoglycan-deficient muscular dystrophy.
Gazzerro, E., Baratto, S., Assereto, S., Baldassari, S., Panicucci, C., Raffaghello, L., Scudieri, P., De Battista, D., Fiorillo, C., Volpi, S., Chaabane, L., Malnati, M., Messina, G., Bruzzone, S., Traggiai, E., Grassi, F., Minetti, C. and Bruno, C.
American Journal of Pathology 189
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February 2019
Suggestions for improving the design of clinical trials in multiple sclerosis - results of a systematic analysis of completed phase III trials.
Gehr, S., Kaiser, T., Kreutz, R., Ludwig, W.D. and Paul, F.
EPMA Journal 10
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December 2019
Olfactory and gustatory dysfunction in patients with autoimmune encephalitis.
Geran, R., Uecker, F.C., Prüss, H., Haeusler, K.G., Paul, F., Ruprecht, K., Harms, L. and Schmidt, F.A.
Frontiers in Neurology 10
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May 2019
Sex differences in autoimmune disorders of the central nervous system.
Gold, S.M., Willing, A., Leypoldt, F., Paul, F. and Friese, M.A.
Seminars in Immunopathology 41
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March 2019
HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M., Yu, Y., Liang, L., Vuralli, D., Froehler, S., Kuehnen, P., Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J., Jia, S., Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7
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May 2019
Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.
Graetz, C., Gröger, A., Luessi, F., Salmen, A., Zöller, D., Schultz, J., Siller, N., Fleischer, V., Bellenberg, B., Berthele, A., Biberacher, V., Havla, J., Hecker, M., Hohlfeld, R., Infante-Duarte, C., Kirschke, J.S., Kümpfel, T., Linker, R., Paul, F., Pfeuffer, S., Sämann, P., Toenges, G., Weber, F., Zettl, U.K., Jahn-Eimermacher, A., Antony, G., Groppa, S., Wiendl, H., Hemmer, B., Mühlau, M., Lukas, C., Gold, R., Lill, C.M. and Zipp, F.
Multiple Sclerosis Journal 25
(5): 661-668.
1 April 2019
CD8(+) T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.
Gross, C.C., Meyer, C., Bhatia, U., Yshii, L., Kleffner, I., Bauer, J., Tröscher, A.R., Schulte-Mecklenbeck, A., Herich, S., Schneider-Hohendorf, T., Plate, H., Kuhlmann, T., Schwaninger, M., Brück, W., Pawlitzki, M., Laplaud, D.A., Loussouarn, D., Parratt, J., Barnett, M., Buckland, M.E., Hardy, T.A., Reddel, S.W., Ringelstein, M., Dörr, J., Wildemann, B., Kraemer, M., Lassmann, H., Höftberger, R., Beltrán, E., Dornmair, K., Schwab, N., Klotz, L., Meuth, S.G., Martin-Blondel, G., Wiendl, H. and Liblau, R.
Nature Communications 10
(1): 5779.
18 December 2019
Serine protease mauritanicain from euphorbia mauritanica and phorbol-12-myristate-13-acetate modulate the IL-8 release in fibroblasts and HaCaT keratinocytes.
Guenther, F., Maus, D., Hedtrich, S. and Melzig, M.F.
Planta Medica 85
(7): 578-582.
May 2019
Brain maturation is associated with increasing tissue stiffness and decreasing tissue fluidity.
Guo, J., Bertalan, G., Meierhofer, D., Klein, C., Schreyer, S., Steiner, B., Wang, S., Vieira da Silva, R., Infante-Duarte, C., Koch, S., Boehm-Sturm, P., Braun, J. and Sack, I.
Acta Biomaterialia 99
: 433-442.
November 2019
Microglia/brain macrophages as central drivers of brain tumor pathobiology.
Gutmann, D.H. and Kettenmann, H.
Neuron 104
(3): 442-449.
6 November 2019
Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism.
Göppner, C., Orozco, I.J., Hoegg-Beiler, M.B., Soria, A.H., Hübner, C.A., Fernandes-Rosa, F.L., Boulkroun, S., Zennaro, M.C. and Jentsch, T.J.
Nature Communications 10
(1): 4678.
15 October 2019
Tenascin C regulates multiple microglial functions involving TLR4 signaling and HDAC1.
Haage, V., Elmadany, N., Roll, L., Faissner, A., Gutmann, D.H., Semtner, M. and Kettenmann, H.
Brain Behavior and Immunity 81
: 470-483.
October 2019
Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.
Haage, V., Semtner, M., Oliveira Vidal, R., Perez Hernandez, D., Pong, W.W., Chen, Z., Hambardzumyan, D., Magrini, V., Ly, A., Walker, J., Mardis, E., Mertins, P., Sauer, S., Kettenmann, H. and Gutmann, D.H.
Acta Neuropathologica Communications 7
(1): 20.
14 February 2019
MRG-1/MRG15 is a barrier for germ cell to neuron reprogramming in Caenorhabditis elegans.
Hajduskova, M., Baytek, G., Kolundzic, E., Gosdschan, A., Kazmierczak, M., Ofenbauer, A., Beato del Rosal, M.L., Herzog, S., ul Fatima, N., Mertins, P., Seelk-Müthel, S. and Tursun, B.
Genetics 211
(1): 121-139.
1 January 2019
The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons.
Handara, G., Hetsch, F.J.A., Jüttner, R., Schick, A., Haupt, C., Rathjen, F.G. and Kröger, S.
Developmental Biology 445
(1): 54-67.
1 January 2019
Regenerative potential of adipocytes in hypertrophic scars is mediated by myofibroblast reprogramming.
Hoerst, K., van den Broek, L., Sachse, C., Klein, O., von Fritschen, U., Gibbs, S. and Hedtrich, S.
Journal of Molecular Medicine 97
(6): 761-775.
1 June 2019
Early hearing loss upon disruption of Slc4a10 in C57BL/6 mice.
Huebner, A.K., Maier, H., Maul, A., Nietzsche, S., Herrmann, T., Praetorius, J. and Hübner, C.A.
Journal of the Association for Research in Otolaryngology 20
(3): 233-245.
June 2019
BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples.
Hörl, D., Rojas Rusak, F., Preusser, F., Tillberg, P., Randel, N., Chhetri, R.K., Cardona, A., Keller, P.J., Harz, H., Leonhardt, H., Treier, M. and Preibisch, S.
Nature Methods 16
(9): 870-874.
September 2019
Live-imaging readouts and cell models for phenotypic profiling of mitochondrial function.
Iannetti, E.F., Prigione, A., Smeitink, J.A.M., Koopman, W.J.H., Beyrath, J. and Renkema, H.
Frontiers in Genetics 10
: 131.
March 2019
Multiple sclerosis-related fatigue: altered resting-state functional connectivity of the ventral striatum and dorsolateral prefrontal cortex.
Jaeger, S., Paul, F., Scheel, M., Brandt, A., Heine, J., Pach, D., Witt, C.M., Bellmann-Strobl, J. and Finke, C.
Multiple Sclerosis Journal 25
(4): 554-564.
April 2019
A combined miRNA-piRNA signature to detect Alzheimer's disease.
Jain, G., Stuendl, A., Rao, P., Berulava, T., Pena Centeno, T., Kaurani, L., Burkhardt, S., Delalle, I., Kornhuber, J., Hüll, M., Maier, W., Peters, O., Esselmann, H., Schulte, C., Deuschle, C., Synofzik, M., Wiltfang, J., Mollenhauer, B., Maetzler, W., Schneider, A. and Fischer, A.
Translational Psychiatry 9
(1): 250.
7 October 2019
Myelinoclastic diffuse sclerosis (Schilder's disease) is immunologically distinct from multiple sclerosis: results from retrospective analysis of 92 lumbar punctures.
Jarius, S., Haas, J., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 16
(1): 51.
28 February 2019
Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).
Johnen, A., Bürkner, P.C., Landmeyer, N.C., Ambrosius, B., Calabrese, P., Motte, J., Hessler, N., Antony, G., König, I.R., Klotz, L., Hoshi, M.M., Aly, L., Groppa, S., Luessi, F., Paul, F., Tackenberg, B., Bergh, F.T., Kümpfel, T., Tumani, H., Stangel, M., Weber, F., Bayas, A., Wildemann, B., Heesen, C., Zettl, U.K., Zipp, F., Hemmer, B., Meuth, S.G., Gold, R., Wiendl, H. and Salmen, A.
Journal of Neurology 266
(2): 386-397.
February 2019
Multiple two-photon targeted whole-cell patch-clamp recordings from monosynaptically connected neurons in vivo.
Jouhanneau, J.S. and Poulet, J.F.A.
Frontiers in Synaptic Neuroscience 11
: 15.
May 2019
Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function.
Jurek, B., Chayka, M., Kreye, J., Lang, K., Kraus, L., Fidzinski, P., Kornau, H.C., Dao, L.M., Wenke, N.K., Long, M., Rivalan, M., Winter, Y., Leubner, J., Herken, J., Mayer, S., Mueller, S., Boehm-Sturm, P., Dirnagl, U., Schmitz, D., Kölch, M. and Prüss, H.
Annals of Neurology 86
(5): 656-670.
November 2019
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes, I., Szulzewsky, F., Chen, Z., Herting, C.J., Gabanic, B., Velázquez Vega, J.E., Shelton, J., Switchenko, J.M., Ross, J.L., McSwain, L.F., Huse, J.T., Westermark, B., Nelander, S., Forsberg-Nilsson, K., Uhrbom, L., Maturi, N.P., Cimino, P.J., Holland, E.C., Kettenmann, H., Brennan, C.W., Brat, D.J. and Hambardzumyan, D.
OncoImmunology 8
(11): e1655360.
22 August 2019
Left prefrontal high-frequency rTMS may improve movement disorder in schizophrenia patients with predominant negative symptoms - a secondary analysis of a sham-controlled, randomized multicenter trial.
Kamp, D., Engelke, C., Wobrock, T., Wölwer, W., Winterer, G., Schmidt-Kraepelin, C., Gaebel, W., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Raees, A., Honer, W.G., Malchow, B., Schneider-Axmann, T., Falkai, P., Hasan, A. and Cordes, J.
Schizophrenia Research 204
: 445-447.
February 2019
The association between frailty and MRI features of cerebral small vessel disease.
Kant, I.M.J., Mutsaerts, H.J.M.M., van Montfort, S.J.T., Jaarsma-Coes, M.G., Witkamp, T.D., Winterer, G., Spies, C.D., Hendrikse, J., Slooter, A.J.C. and de Bresser, J.
Scientific Reports 9
(1): 11343.
5 August 2019
MTrack: automated detection, tracking, and analysis of dynamic microtubules.
Kapoor, V., Hirst, W.G., Hentschel, C., Preibisch, S. and Reber, S.
Scientific Reports 9
(1): 3794.
7 March 2019
Recruitment of histone methyltransferase Ehmt1 to Foxp3 TSDR counteracts differentiation of induced regulatory T cells.
Karl, M., Sommer, C., Gabriel, C.H., Hecklau, K., Venzke, M., Hennig, A.F., Radbruch, A., Selbach, M. and Baumgrass, R.
Journal of Molecular Biology 431
(19): 3606-3625.
6 September 2019
Lyophilization of synthetic gene carriers.
Kasper, J.C., Hedtrich, S. and Friess, W.
Methods in Molecular Biology 1943
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2019
Automatic quality evaluation as assessment standard for optical coherence tomography.
Kauer, J., Gawlik, K., Zimmermann, H.G., Kadas, E.M., Bereuter, C., Paul, F., Brandt, A.U., Hausser, F. and Beckers, I.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, United States.
26 February 2019
Histological and functional comparisons of four anatomical regions of porcine skin with human abdominal skin.
Khiao In, M., Richardson, K.C., Loewa, A., Hedtrich, S., Kaessmeyer, S. and Plendl, J.
Anatomia Histologia Embryologia 48
(3): 207-217.
May 2019
Quantitative grip force assessment of muscular weakness in chronic inflammatory demyelinating polyneuropathy.
Klehmet, J., Beutner, S., Hoffmann, S., Dornauer, M., Paul, F., Reilmann, R., Brandt, A.U. and Meisel, A.
BMC Neurology 19
(1): 118.
8 June 2019
Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.
Kosciuczuk, E.M., Mehrotra, S., Saleiro, D., Kroczynska, B., Majchrzak-Kita, B., Lisowski, P., Driehaus, C., Rogalska, A., Turner, A., Lienhoop, T., Gius, D., Fish, E.N., Vassilopoulos, A. and Platanias, L.C.
Journal of Biological Chemistry 294
(3): 827-837.
18 January 2019
MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.
Kotelnikova, E., Kiani, N.A., Messinis, D., Pertsovskaya, I., Pliaka, V., Bernardo-Faura, M., Rinas, M., Vila, G., Zubizarreta, I., Pulido-Valdeolivas, I., Sakellaropoulos, T., Faigle, W., Silberberg, G., Masso, M., Stridh, P., Behrens, J., Olsson, T., Martin, R., Paul, F., Alexopoulos, L.G., Saez-Rodriguez, J., Tegner, J. and Villoslada, P.
Proceedings of the National Academy of Sciences of the United States of America 116
(19): 9671-9676.
7 May 2019
Less is more - estimation of the number of strides required to assess gait variability in spatially confined settings.
Kroneberg, D., Elshehabi, M., Meyer, A.C., Otte, K., Doss, S., Paul, F., Nussbaum, S., Berg, D., Kühn, A.A., Maetzler, W. and Schmitz-Hübsch, T.
Frontiers in Aging Neuroscience 10
: 435.
21 January 2019
Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi, V., Peng, S., Klironomos, F., Munschauer, M., Kastelic, N., Chakraborty, T., Schoeler, K., Derudder, E., Martella, M., Mastrobuoni, G., Hernandez-Miranda, L.R., Lahmann, I., Kocks, C., Birchmeier, C., Kempa, S., Quintanilla-Martinez de Fend, L., Landthaler, M., Rajewsky, N. and Rajewsky, K.
Genes & Development 33
: 23-24.
7 November 2019
Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I., Bröhl, D., Zyrianova, T., Isomura, A., Czajkowski, M.T., Kapoor, V., Griger, J., Ruffault, P.L., Mademtzoglou, D., Zammit, P.S., Wunderlich, T., Spuler, S., Kühn, R., Preibisch, S., Wolf, J., Kageyama, R. and Birchmeier, C.
Genes & Development 33
(9-10): 524-535.
1 May 2019
Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial.
Levin, J., Maaß, S., Schuberth, M., Giese, A., Oertel, W.H., Poewe, W., Trenkwalder, C., Wenning, G.K., Mansmann, U., Südmeyer, M., Eggert, K., Mollenhauer, B., Lipp, A., Löhle, M., Classen, J., Münchau, A., Kassubek, J., Gandor, F., Berg, D., Egert-Schwender, S., Eberhardt, C., Paul, F., Bötzel, K., Ertl-Wagner, B., Huppertz, H.J., Ricard, I. and Höglinger, G.U.
Lancet Neurology 18
(8): 724-735.
August 2019
Diversity in the lab makes me a better scientist.
Lowenstein, E.
Scientific American 320
(1): 8.
January 2019
Genome-wide analysis of RNA and protein localization and local translation in mESC-derived neurons.
Ludwik, K.A., von Kuegelgen, N. and Chekulaeva, M.
Methods 162-163
: 31-41.
June 2019
Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses.
Maglione, M., Kochlamazashvili, G., Eisenberg, T., Rácz, B., Michael, E., Toppe, D., Stumpf, A., Wirth, A., Zeug, A., Müller, F.E., Moreno-Velasquez, L., Sammons, R.P., Hofer, S.J., Madeo, F., Maritzen, T., Maier, N., Ponimaskin, E., Schmitz, D., Haucke, V. and Sigrist, S.J.
Scientific Reports 9
(1): 19616.
23 December 2019
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Marg, A., Escobar Fernandez, H., Karaiskos, N., Grunwald, S.A., Metzler, E., Kieshauer, J., Sauer, S., Pasemann, D., Malfatti, E., Mompoint, D., Quijano-Roy, S., Boltengagen, A., Schneider, J., Schülke, M., Kunz, S., Carlier, R., Birchmeier, C., Amthor, H., Spuler, A., Kocks, C., Rajewsky, N. and Spuler, S.
Nature Communications 10
(1): 5776.
18 December 2019
The author file: Stephan Preibisch.
Marx, V.
Nature Methods 16
(9): 793.
September 2019
eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization.
Matthaeus, C., Lian, X., Kunz, S., Lehmann, M., Zhong, C., Bernert, C., Lahmann, I., Müller, D.N., Gollasch, M. and Daumke, O.
PLoS ONE 14
(10): e0223620.
10 October 2019
A gene expression atlas of embryonic neurogenesis in Drosophila reveals complex spatiotemporal regulation of lncRNAs.
McCorkindale, A.L., Wahle, P., Werner, S., Jungreis, I., Menzel, P., Shukla, C.J., Abreu, R.L.P., Irizarry, R.A., Meyer, I.M., Kellis, M. and Zinzen, R.P.
Development 146
(6): dev175265.
28 March 2019
Long-term disability in neuromyelitis optica spectrum disorder with a history of myelitis is associated with age at onset, delay in diagnosis/preventive treatment, MRI lesion length and presence of symptomatic brain lesions.
Mealy, M.A., Mossburg, S.E., Kim, S.H., Messina, S., Borisow, N., Lopez-Gonzalez, R., Ospina, J.P., Scheel, M., Yeshokumar, A.K., Awad, A., Leite, M.I., Arango, J.A.J., Paul, F., Palace, J., Kim, H.J. and Levy, M.
Multiple Sclerosis and Related Disorders 28
: 64-68.
February 2019
Transcriptional dynamics of microRNAs and their targets during Drosophila neurogenesis.
Menzel, P., McCorkindale, A.L., Stefanov, S.R., Zinzen, R.P. and Meyer, I.M.
RNA Biology 16
(1): 69-81.
20 January 2019
240th ENMC workshop: The involvement of skeletal muscle stem cells in the pathology of muscular dystrophies 25–27 January 2019, Hoofddorp, The Netherlands.
Morgan, J., Butler-Browne, G., Muntoni, F. and Patel, K.
Neuromuscular Disorders 29
(9): 704-715.
2019
Normative data and minimally detectable change for inner retinal layer thicknesses using a semi-automated OCT image segmentation pipeline.
Motamedi, S., Gawlik, K., Ayadi, N., Zimmermann, H.G., Asseyer, S., Bereuter, C., Mikolajczak, J., Paul, F., Kadas, E.M. and Brandt, A.U.
Frontiers in Neurology 10
: 1117.
November 2019
Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A., Sengul, T.G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M.H., Ofenbauer, A., Gesell-Salazar, M., Balogh, A., Kempa, S., Tursun, B., Robbins, C.T., Völker, U., Chen, W., Nelson, L. and Gotthardt, M.
Scientific Reports 9
(1): 19976.
27 December 2019
The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S., Uyar, B., He, M., Krause, A., Vitrinel, B., Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S., Akalin, A. and Tursun, B.
Aging Cell 18
(6): e13012.
December 2019
Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: an international study.
Nolan, R.C., Liu, M., Akhand, O., Calabresi, P.A., Paul, F., Petzold, A., Balk, L., Brandt, A.U., Martínez-Lapiscina, E.H., Saidha, S., Villoslada, P., Abu Al-Hassan, A., Behbehani, R., Frohman, E.M., Frohman, T., Havla, J., Hemmer, B., Jiang, H., Knier, B., Korn, T., Leocani, L., Papadopoulou, A., Pisa, M., Zimmermann, H., Galetta, S.L. and Balcer, L.J.
Annals of Neurology 85
(5): 618-629.
May 2019
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
Nowak, M., Suenkel, B., Porras, P., Migotti, R., Schmidt, F., Kny, M., Zhu, X., Wanker, E.E., Dittmar, G., Fielitz, J. and Sommer, T.
Journal of Cell Science 132
(17): jcs233395.
6 September 2019
Defining orphan conditions in the context of the European orphan regulation: challenges and evolution.
O'Connor, D.J., Sheean, M.E., Hofer, M.P., Tsigkos, S., Mariz, S., Fregonese, L., Larsson, K., Hivert, V., Westermark, K., Naumann-Winter, F., Stoyanova-Beninska, V., Barišić, I., Capovilla, G., Magrelli, A. and Sepodes, B.
Nature Reviews Drug Discovery 18
(7): 479-480.
July 2019
Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study.
Oertel, F.C., Outteryck, O., Knier, B., Zimmermann, H., Borisow, N., Bellmann-Strobl, J., Blaschek, A., Jarius, S., Reindl, M., Ruprecht, K., Meinl, E., Hohlfeld, R., Paul, F., Brandt, A.U., Kümpfel, T. and Havla, J.
Journal of Neuroinflammation 16
(1): 154.
25 July 2019
Cognitive impairment in neuromyelitis optica spectrum disorders: a review of clinical and neuroradiological features.
Oertel, F.C., Schließeit, J., Brandt, A.U. and Paul, F.
Frontiers in Neurology 10
: 608.
12 June 2019
Novel uses of retinal imaging with optical coherence tomography in multiple sclerosis.
Oertel, F.C., Zimmermann, H.G., Brandt, A.U. and Paul, F.
Expert Review of Neurotherapeutics 19
(1): 31-43.
2 January 2019
Strategies for in vivo reprogramming.
Ofenbauer, A. and Tursun, B.
Current Opinion in Cell Biology 61
: 9-15.
December 2019
Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study.
Olesen, M.N., Soelberg, K., Debrabant, B., Nilsson, A.C., Lillevang, S.T., Grauslund, J., Brandslund, I., Madsen, J.S., Paul, F., Smith, T.J., Jarius, S. and Asgari, N.
Journal of Neuroinflammation 16
(1): 59.
11 March 2019
Calcium-independent exo-endocytosis coupling at small central synapses.
Orlando, M., Schmitz, D., Rosenmund, C. and Herman, M.A.
Cell Reports 29
(12): 3767-3774.
17 December 2019
Low-density granulocytes are a novel immunopathological feature in both multiple sclerosis and neuromyelitis optica spectrum disorder.
Ostendorf, L., Mothes, R., van Koppen, S., Lindquist, R.L., Bellmann-Strobl, J., Asseyer, S., Ruprecht, K., Alexander, T., Niesner, R.A., Hauser, A.E., Paul, F. and Radbruch, H.
Frontiers in Immunology 10
: 2725.
29 November 2019
Damage of the lateral geniculate nucleus in MS: assessing the missing node of the visual pathway.
Papadopoulou, A., Gaetano, L., Pfister, A., Altermatt, A., Tsagkas, C., Morency, F., Brandt, A.U., Hardmeier, M., Chakravarty, M.M., Descoteaux, M., Kappos, L., Sprenger, T. and Magon, S.
Neurology 92
(19): e2240-e2249.
7 May 2019
Attack-related damage of thalamic nuclei in neuromyelitis optica spectrum disorders.
Papadopoulou, A., Oertel, F.C., Gaetano, L., Kuchling, J., Zimmermann, H., Chien, C., Siebert, N., Asseyer, S., Bellmann-Strobl, J., Ruprecht, K., Chakravarty, M.M., Scheel, M., Magon, S., Wuerfel, J., Paul, F. and Brandt, A.U.
Journal of Neurology Neurosurgery and Psychiatry 90
(10): 1156-1164.
October 2019
Quantitative 7T MRI does not detect occult brain damage in neuromyelitis optica.
Pasquier, B., Borisow, N., Rasche, L., Bellmann-Strobl, J., Ruprecht, K., Niendorf, T., Derfuss, T.J., Wuerfel, J., Paul, F. and Sinnecker, T.
Neurology Neuroimmunology & Neuroinflammation 6
(3): e541.
May 2019
The use of magnetic resonance imaging in the diagnosis of paediatric transverse myelitis.
Paul, F.
Developmental Medicine and Child Neurology 61
(9): 1001.
September 2019
Flammer syndrome and autoimmune inflammatory conditions of the central nervous system: multifactorial interrelations.
Paul, F.
Advances in Predictive, Preventive and Personalised Medicine 11
: 145-163.
2019
Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.
Pfuhl, C., Grittner, U., Gieß, R.M., Scheel, M., Behrens, J.R., Rasche, L., Pache, F.C., Wenzel, R., Brandt, A.U., Bellmann-Strobl, J., Paul, F., Ruprecht, K. and Oechtering, J.
Neurology 93
(15): e1439-e1451.
8 October 2019
Transglutaminase 1 replacement therapy successfully mitigates the autosomal recessive congenital ichthyosis phenotype in full-thickness skin disease equivalents.
Plank, R., Yealland, G., Miceli, E., Lima Cunha, D., Graff, P., Thomforde, S., Gruber, R., Moosbrugger-Martinz, V., Eckl, K., Calderón, M., Hennies, H.C. and Hedtrich, S.
Journal of Investigative Dermatology 139
(5): 1191-1195.
May 2019
The cortical states of wakefulness.
Poulet, J.F.A. and Crochet, S.
Frontiers in Systems Neuroscience 12
: 64.
January 2019
Comparison of zebrafish and mice knockouts for Megalencephalic Leukoencephalopathy proteins indicates that GlialCAM/MLC1 forms a functional unit.
Pérez-Rius, C., Folgueira, M., Elorza-Vidal, X., Alia, A., Hoegg-Beiler, M.B., Eeza, M.N.H., Díaz, M.L., Nunes, V., Barrallo-Gimeno, A. and Estévez, R.
Orphanet Journal of Rare Diseases 14
(1): 268.
21 November 2019
The central nervous system contains ILC1s that differ from NK cells in the response to inflammation.
Romero-Suárez, S., Del Rio Serrato, A., Bueno, R.J., Brunotte-Strecker, D., Stehle, C., Figueiredo, C.A., Hertwig, L., Dunay, I.R., Romagnani, C. and Infante-Duarte, C.
Frontiers in Immunology 10
: 2337.
10 October 2019
Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes.
Rudolph, F., Hüttemeister, J., da Silva Lopes, K., Jüttner, R., Yu, L., Bergmann, N., Friedrich, D., Preibisch, S., Wagner, E., Lehnart, S.E., Gregorio, C.C. and Gotthardt, M.
Proceedings of the National Academy of Sciences of the United States of America 116
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10 December 2019
Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.
Rydzanicz, M., Wachowska, M., Cook, E.C., Lisowski, P., Kuźniewska, B., Szymańska, K., Diecke, S., Prigione, A., Szczałuba, K., Szybińska, A., Koppolu, A., Murcia Pienkowski, V., Kosińska, J., Wiweger, M., Kostrzewa, G., Brzozowska, M., Domańska-Pakieła, D., Jurkiewicz, E., Stawiński, P., Gromadka, A., Zielenkiewicz, P., Demkow, U., Dziembowska, M., Kuźnicki, J., Creamer, T.P. and Płoski, R.
European Journal of Human Genetics 27
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January 2019
Electrophysiological and molecular characterization of the parasubiculum.
Sammons, R.P., Parthier, D., Stumpf, A. and Schmitz, D.
Journal of Neuroscience 39
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6 November 2019
Definition and quantification of six immune- and neuroregulatory serum proteins in healthy and demented elderly.
Schipke, C.G., Günter, O., Weinert, C., Scotton, P., Sigle, J.P., Kallarackal, J., Kabelitz, D., Finzen, A. and Feuerhelm-Heidl, A.
Neurodegenerative Disease Management 9
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August 2019
Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking.
Schmidtke, C., Tiede, S., Thelen, M., Käkelä, R., Jabs, S., Makrypidi, G., Sylvester, M., Schweizer, M., Braren, I., Brocke-Ahmadinejad, N., Cotman, S.L., Schulz, A., Gieselmann, V. and Braulke, T.
Journal of Biological Chemistry 294
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14 June 2019
Cien años de microglía: milestones in a century of microglial research.
Sierra, A., Paolicelli, R.C. and Kettenmann, H.
Trends in Neurosciences 42
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November 2019
Evaluation of the central vein sign as a diagnostic imaging biomarker in multiple sclerosis.
Sinnecker, T., Clarke, M.A., Meier, D., Enzinger, C., Calabrese, M., De Stefano, N., Pitiot, A., Giorgio, A., Schoonheim, M.M., Paul, F., Pawlak, M.A., Schmidt, R., Kappos, L., Montalban, X., Rovira, À., Evangelou, N. and Wuerfel, J.
JAMA Neurology 76
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December 2019
Neurodevelopmental disorder associated with IRF2BPL gene mutation: expanding the phenotype?
Skorvanek, M., Dusek, P., Rydzanicz, M., Walczak, A., Kosinska, J., Kostrzewa, G., Rydzanicz, M., Han, V., Dosekova, P., Gdovinova, Z., Lehotska, Z., Lisowski, P. and Ploski, R.
Parkinsonism & Related Disorders 62
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24 January 2019
Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Starossom, S.C., Campo Garcia, J., Woelfle, T., Romero-Suarez, S., Olah, M., Watanabe, F., Cao, L., Yeste, A., Tukker, J.J., Quintana, F.J., Imitola, J., Witzel, F., Schmitz, D., Morkel, M., Paul, F., Infante-Duarte, C. and Khoury, S.J.
Nature Communications 10
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15 January 2019
Does time equal vision in the acute treatment of a cohort of AQP4 and MOG optic neuritis?
Stiebel-Kalish, H., Hellmann, M.A., Mimouni, M., Paul, F., Bialer, O., Bach, M. and Lotan, I.
Neurology Neuroimmunology & Neuroinflammation 6
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July 2019
A convex relaxation for multi-graph matching.
Swoboda, P., Kainmüller, D., Mokarian, A., Theobalt, C. and Bernard, F.
In: 2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 16-20 Jun 2019, Long Beach, CA, USA.
2019
Identification of proteins and miRNAs that specifically bind an mRNA in vivo.
Theil, K., Imami, K. and Rajewsky, N.
Nature Communications 10
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16 September 2019
Critical parameters for the controlled synthesis of nanogels suitable for temperature-triggered protein delivery.
Theune, L.E., Charbaji, R., Kar, M., Wedepohl, S., Hedtrich, S. and Calderón, M.
Materials Science and Engineering C: Materials for Biological Applications 100
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July 2019
Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels.
Ullrich, F., Blin, S., Lazarow, K., Daubitz, T., von Kries, J.P. and Jentsch, T.J.
eLife 8
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18 July 2019
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta, E.C., Vieira-Vieira, C.H., Hick, T., Wessels, H.H., Figini, D., Moschall, R., Medenbach, J., Ohler, U., Granneman, S., Selbach, M. and Beckmann, B.M.
Nature Communications 10
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1 March 2019
Multiple sclerosis.
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Contactless recording of sleep apnea and periodic leg movements by nocturnal 3-D-video and subsequent visual perceptive computing.
Veauthier, C., Ryczewski, J., Mansow-Model, S., Otte, K., Kayser, B., Glos, M., Schöbel, C., Paul, F., Brandt, A.U. and Penzel, T.
Scientific Reports 9
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14 November 2019
Association of a PD-L2 gene polymorphism with chronic lymphatic filariasis in a South Indian cohort.
Venugopal, G., O'Regan, N.L., Babu, S., Schumann, R.R., Srikantam, A., Merle, R., Hartmann, S. and Steinfelder, S.
American Journal of Tropical Medicine and Hygiene 100
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February 2019
Efficacy of high-frequency repetitive transcranial magnetic stimulation in schizophrenia patients with treatment-resistant negative symptoms treated with clozapine.
Wagner, E., Wobrock, T., Kunze, B., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Cordes, J., Wölwer, W., Winterer, G., Gaebel, W., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Siskind, D., Malchow, B., Strube, W., Schneider-Axmann, T., Falkai, P. and Hasan, A.
Schizophrenia Research 208
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June 2019
Increased retention of gadolinium in the inflamed brain after repeated administration of gadopentetate dimeglumine: a proof-of-concept study in mice combining ICP-MS and micro- and nano-SR-XRF.
Wang, S., Hesse, B., Roman, M., Stier, D., Castillo-Michel, H., Cotte, M., Suuronen, J.P., Lagrange, A., Radbruch, H., Paul, F., Taupitz, M., Schellenberger, E., Sack, I. and Infante-Duarte, C.
Investigative Radiology 54
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October 2019
The pathobiology of perturbed mutant huntingtin protein-protein interactions in Huntington's disease.
Wanker, E.E., Ast, A., Schindler, F., Trepte, P. and Schnoegl, S.
Journal of Neurochemistry 151
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November 2019
3D organ models-Revolution in pharmacological research?
Weinhart, M., Hocke, A., Hippenstiel, S., Kurreck, J. and Hedtrich, S.
Pharmacological Research 139
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January 2019
Neural mechanisms of perceptual decision-making and their link to neuropsychiatric symptoms in multiple sclerosis.
Weygandt, M., Behrens, J., Brasanac, J., Söder, E., Meyer-Arndt, L., Wakonig, K., Ritter, K., Brandt, A.U., Bellmann-Strobl, J., Gold, S.M., Haynes, J.D. and Paul, F.
Multiple Sclerosis and Related Disorders 33
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August 2019
Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial.
Wirth, M., Schwarz, C., Benson, G., Horn, N., Buchert, R., Lange, C., Köbe, T., Hetzer, S., Maglione, M., Michael, E., Märschenz, S., Mai, K., Kopp, U., Schmitz, D., Grittner, U., Sigrist, S.J., Stekovic, S., Madeo, F. and Flöel, A.
Alzheimer's Research & Therapy 11
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1 May 2019
CRISPR-activation-based screen reveals neuronal fate promotion by polycomb repressive complex 2 during direct reprogramming.
Wolfram, T. and Tursun, B.
Stem Cell Investigation 6
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September 2019
Muscle wasting and function after muscle activation and early protocol-based physiotherapy: an explorative trial.
Wollersheim, T., Grunow, J.J., Carbon, N.M., Haas, K., Malleike, J., Ramme, S.F., Schneider, J., Spies, C.D., Märdian, S., Mai, K., Spuler, S., Fielitz, J. and Weber-Carstens, S.
Journal of Cachexia Sarcopenia and Muscle 10
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August 2019
The cell adhesion protein CAR is a negative regulator of synaptic transmission.
Wrackmeyer, U., Kaldrack, J., Jüttner, R., Pannasch, U., Gimber, N., Freiberg, F., Purfürst, B., Kainmueller, D., Schmitz, D., Haucke, V., Rathjen, F.G. and Gotthardt, M.
Scientific Reports 9
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1 May 2019
HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K., Franke, V., Uyar, B., Wurmus, R., Bulut, S., Tursun, B. and Akalin, A.
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20 June 2019
One-pot synthesis of poly(glycerol-co-succinic acid) nanogels for dermal delivery.
Zabihi, F., Koeppe, H., Achazi, K., Hedtrich, S. and Haag, R.
Biomacromolecules 20
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13 May 2019
Integrated phosphoproteome and transcriptome analysis reveals Chlamydia-induced epithelial-to-mesenchymal transition in host cells.
Zadora, P.K., Chumduri, C., Imami, K., Berger, H., Mi, Y., Selbach, M., Meyer, T.F. and Gurumurthy, R.K.
Cell Reports 26
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29 January 2019
Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations.
Zhao, W., Bohleber, S., Schmidt, H., Seeher, S., Howard, M.T., Braun, D., Arndt, S., Reuter, U., Wende, H., Birchmeier, C., Fradejas-Villar, N. and Schweizer, U.
Journal of Biological Chemistry 294
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27 September 2019
Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V., McShane, E., Schulz-Beiss, K.W., Patone, G., Schleussner, N., Kolesnichenko, M., Hübner, N., Daumke, O., Selbach, M., Akalin, A., Mathas, S. and Scheidereit, C.
Blood 133
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28 March 2019
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Polarity acquisition in cortical neurons is driven by synergistic action of Sox9-regulated Wwp1 and Wwp2 E3 ubiquitin ligases and intronic miR-140.
Ambrozkiewicz, M.C., Schwark, M., Kishimoto-Suga, M., Borisova, E., Hori, K., Salazar-Lázaro, A., Rusanova, A., Altas, B., Piepkorn, L., Bessa, P., Schaub, T., Zhang, X., Rabe, T., Ripamonti, S., Rosário, M., Akiyama, H., Jahn, O., Kobayashi, T., Hoshino, M., Tarabykin, V. and Kawabe, H.
Neuron 100
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5 December 2018
Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.
Arnoux, I., Willam, M., Griesche, N., Krummeich, J., Watari, H., Offermann, N., Weber, S., Narayan Dey, P., Chen, C., Monteiro, O., Buettner, S., Meyer, K., Bano, D., Radyushkin, K., Langston, R., Lambert, J.J., Wanker, E., Methner, A., Krauss, S., Schweiger, S. and Stroh, A.
eLife 7
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4 September 2018
Pain in AQP4-IgG-positive and MOG-IgG-positive neuromyelitis optica spectrum disorders.
Asseyer, S., Schmidt, F., Chien, C., Scheel, M., Ruprecht, K., Bellmann-Strobl, J., Brandt, A.U. and Paul, F.
Multiple Sclerosis Journal Experimental Translational and Clinical 4
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1 July 2018
mHTT seeding activity: a marker of disease progression and neurotoxicity in models of Huntington's disease.
Ast, A., Buntru, A., Schindler, F., Hasenkopf, R., Schulz, A., Brusendorf, L., Klockmeier, K., Grelle, G., McMahon, B., Niederlechner, H., Jansen, I., Diez, L., Edel, J., Boeddrich, A., Franklin, S.A., Baldo, B., Schnoegl, S., Kunz, S., Purfürst, B., Gaertner, A., Kampinga, H.H., Morton, A.J., Petersén, Å., Kirstein, J., Bates, G.P. and Wanker, E.E.
Molecular Cell 71
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6 September 2018
A filter retardation assay facilitates the detection and quantification of heat-stable, amyloidogenic mutant huntingtin aggregates in complex biosamples.
Ast, A., Schindler, F., Buntru, A., Schnoegl, S. and Wanker, E.E.
Methods in Molecular Biology 1780
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2018
Temporal visual resolution and disease severity in MS.
Ayadi, N., Dörr, J., Motamedi, S., Gawlik, K., Bellmann-Strobl, J., Mikolajczak, J., Brandt, A.U., Zimmermann, H. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 5
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1 September 2018
Anatomical wiring and functional networking changes in the visual system following optic neuritis.
Backner, Y., Kuchling, J., Massarwa, S., Oberwahrenbrock, T., Finke, C., Bellmann-Strobl, J., Ruprecht, K., Brandt, A.U., Zimmermann, H., Raz, N., Paul, F. and Levin, N.
JAMA Neurology 75
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March 2018
The International Multiple Sclerosis Visual System Consortium: advancing visual system research in multiple sclerosis.
Balcer, L.J., Balk, L.J., Brandt, A.U., Calabresi, P.A., Martinez-Lapiscina, E.H., Nolan, R.C., Paul, F., Petzold, A. and Saidha, S.
Journal of Neuro-Ophthalmology 38
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December 2018
Role of VTA dopamine neurons and neuroligin 3 in sociability traits related to nonfamiliar conspecific interaction.
Bariselli, S., Hörnberg, H., Prévost-Solié, C., Musardo, S., Hatstatt-Burklé, L., Scheiffele, P. and Bellone, C.
Nature Communications 9
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9 August 2018
7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions.
Behrens, J.R., Wanner, J., Kuchling, J., Ostendorf, L., Harms, L., Ruprecht, K., Niendorf, T., Jarius, S., Wildemann, B., Gieß, R.M., Scheel, M., Bellmann-Strobl, J., Wuerfel, J., Paul, F. and Sinnecker, T.
Annals of Clinical and Translational Neurology 5
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August 2018
CCR7 on CD4(+) T cells plays a crucial role in the induction of experimental autoimmune encephalomyelitis.
Belikan, P., Bühler, U., Wolf, C., Pramanik, G.K., Gollan, R., Zipp, F. and Siffrin, V.
Journal of Immunology 200
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15 April 2018
The effectiveness of acupuncture and mindfulness-based stress reduction (MBSR) for patients with multiple sclerosis associated fatigue: a study protocol and its rationale for a randomized controlled trial.
Bellmann-Strobl, J., Pach, D., Chang, Y., Pasura, L., Liu, B., Jäger, S.F., Loerch, R., Jin, L., Blödt, S., Brinkhaus, B., Ortiz, M., Reinhold, T., Roll, S., Binting, S., Paul, F., Witt, C.M. and Shi, X.
European Journal of Integrative Medicine 20
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June 2018
Potassium channel-based optogenetic silencing.
Bernal Sierra, Y.A., Rost, B.R., Pofahl, M., Fernandes, A.M., Kopton, R.A., Moser, S., Holtkamp, D., Masala, N., Beed, P., Tukker, J.J., Oldani, S., Bönigk, W., Kohl, P., Baier, H., Schneider-Warme, F., Hegemann, P., Beck, H., Seifert, R. and Schmitz, D.
Nature Communications 9
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5 November 2018
Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid.
Birol, M., Kumar, S., Rhoades, E. and Miranker, A.D.
Nature Communications 9
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3 April 2018
Omics-based approach reveals complement-mediated inflammation in chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).
Blaabjerg, M., Hemdrup, A.L., Drici, L., Ruprecht, K., Garred, P., Höftberger, R., Kristensen, B.W., Kondziella, D., Sejbaek, T., Hansen, S.W., Nielsen, H.H., Jensen, P., Meyer, M., Paul, F., Lassmann, H., Larsen, M.R. and Illes, Z.
Frontiers in Immunology 9
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23 April 2018
Ketogenic diets attenuate cyclooxygenase and lipoxygenase gene expression in multiple sclerosis.
Bock, M., Karber, M. and Kuhn, H.
EBioMedicine 36
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October 2018
Somatostatin 2 receptor activation in the rostral ventrolateral medulla does not mediate the decompensatory phase of haemorrhage.
Bokiniec, P., Burke, P.G.R., Turner, A.J., McMullan, S. and Goodchild, A.K.
Shock 50
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September 2018
The neural circuits of thermal perception.
Bokiniec, P., Zampieri, N., Lewin, G.R. and Poulet, J.F.A.
Current Opinion in Neurobiology 52
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October 2018
Neuromyelitis optica spectrum disorders and pregnancy: relapse-preventive measures and personalized treatment strategies.
Borisow, N., Hellwig, K. and Paul, F.
EPMA Journal 9
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September 2018
Neuromyelitis-optica-Spektrum-Erkrankung und Schwangerschaft [Neuromyelitis optica spectrum disorder and pregnancy].
Borisow, N., Hellwig, K. and Paul, F.
Nervenarzt 89
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June 2018
Diagnosis and treatment of NMO spectrum disorder and MOG-encephalomyelitis.
Borisow, N., Mori, M., Kuwabara, S., Scheel, M. and Paul, F.
Frontiers in Neurology 9
: 888.
October 2018
Frequent retinal ganglion cell damage after acute optic neuritis.
Brandt, A.U., Specovius, S., Oberwahrenbrock, T., Zimmermann, H.G., Paul, F. and Costello, F.
Multiple Sclerosis and Related Disorders 22
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May 2018
Self-perception and determinants of color vision in Parkinson's disease.
Brandt, A.U., Zimmermann, H.G., Oberwahrenbrock, T., Isensee, J., Müller, T. and Paul, F.
Journal of Neural Transmission 125
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February 2018
The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.
Bégay, V., Baumeier, C., Zimmermann, K., Heuser, A. and Leutz, A.
Scientific Reports 8
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30 May 2018
Routes to, from and within the subiculum.
Böhm, C., Peng, Y., Geiger, J.R.P. and Schmitz, D.
Cell and Tissue Research 373
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September 2018
Sustained MAPK/ERK activation in adult Schwann cells impairs nerve repair.
Cervellini, I., Galino, J., Zhu, N., Allen, S., Birchmeier, C. and Bennett, D.L.
Journal of Neuroscience 38
(3): 679-690.
17 January 2018
Longitudinal study of multiple sclerosis lesions using ultra-high field (7T) multiparametric MR imaging.
Chawla, S., Kister, I., Sinnecker, T., Wuerfel, J., Brisset, J.C., Paul, F. and Ge, Y.
PLoS ONE 13
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13 September 2018
MRI-based methods for spinal cord atrophy evaluation: a comparison of cervical cord cross-sectional area, cervical cord volume, and full spinal cord volume in patients with aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders.
Chien, C., Brandt, A.U., Schmidt, F., Bellmann-Strobl, J., Ruprecht, K., Paul, F. and Scheel, M.
American Journal of Neuroradiology 39
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1 July 2018
Intestinal electrolyte and fluid secretion: a model in trouble?
Cid, L.P., Jentsch, T.J. and Sepúlveda, F.V.
Journal of Physiology 596
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15 June 2018
Barreloid borders and neuronal activity shape panglial gap junction-coupled networks in the mouse thalamus.
Claus, L., Philippot, C., Griemsmann, S., Timmermann, A., Jabs, R., Henneberger, C., Kettenmann, H. and Steinhaeuser, C.
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1 January 2018
Low-frequency and rare-coding variation contributes to multiple sclerosis risk.
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Cell 175
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29 November 2018
Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability.
Dawes, J.M., Weir, G.A., Middleton, S.J., Patel, R., Chisholm, K.I., Pettingill, P., Peck, L.J., Sheridan, J., Shakir, A., Jacobson, L., Gutierrez-Mecinas, M., Galino, J., Walcher, J., Kühnemund, J., Kuehn, H., Sanna, M.D., Lang, B., Clark, A.J., Themistocleous, A.C., Iwagaki, N., West, S.J., Werynska, K., Carroll, L., Trendafilova, T., Menassa, D.A., Giannoccaro, M.P., Coutinho, E., Cervellini, I., Tewari, D., Buckley, C., Leite, M.I., Wildner, H., Zeilhofer, H.U., Peles, E., Todd, A.J., McMahon, S.B., Dickenson, A.H., Lewin, G.R., Vincent, A. and Bennett, D.L.
Neuron 97
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21 February 2018
Nuclear organization in the spinal cord depends on motor neuron lamination orchestrated by catenin and afadin function.
Dewitz, C., Pimpinella, S., Hackel, P., Akalin, A., Jessell, T.M. and Zampieri, N.
Cell Reports 22
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13 February 2018
Muscle MRI in patients with dysferlinopathy: pattern recognition and implications for clinical trials.
Diaz-Manera, J., Fernandez-Torron, R., LLauger, J., James, M.K., Mayhew, A., Smith, F.E., Moore, U.R., Blamire, A.M., Carlier, P.G., Rufibach, L., Mittal, P., Eagle, M., Jacobs, M., Hodgson, T., Wallace, D., Ward, L., Smith, M., Stramare, R., Rampado, A., Sato, N., Tamaru, T., Harwick, B., Rico Gala, S., Turk, S., Coppenrath, E.M., Foster, G., Bendahan, D., Le Fur, Y., Fricke, S.T., Otero, H., Foster, S.L., Peduto, A., Sawyer, A.M., Hilsden, H., Lochmuller, H., Grieben, U., Spuler, S., Tesi Rocha, C., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Harms, M., Pestronk, A., Krause, S., Schreiber-Katz, O., Walter, M.C., Paradas, C., Hogrel, J.Y., Stojkovic, T., Takeda, S., Mori-Yoshimura, M., Bravver, E., Sparks, S., Bello, L., Semplicini, C., Pegoraro, E., Mendell, J.R., Bushby, K. and Straub, V.
Journal of Neurology Neurosurgery and Psychiatry 89
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October 2018
Hippocampal ripple oscillations and inhibition-first network models: frequency dynamics and response to GABA modulators.
Donoso, J.R., Schmitz, D., Maier, N. and Kempter, R.
Journal of Neuroscience 38
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21 March 2018
S-palmitoylation is required for the control of growth cone morphology of DRG neurons by CNP-induced cGMP signaling.
Dumoulin, A., Dagane, A., Dittmar, G. and Rathjen, F.G.
Frontiers in Molecular Neuroscience 11
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24 September 2018
Molecular analysis of sensory axon branching unraveled a cGMP-dependent signaling cascade.
Dumoulin, A., Ter-Avetisyan, G., Schmidt, H. and Rathjen, F.G.
International Journal of Molecular Sciences 19
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24 April 2018
Glutamate uptake and release at single adult corticostriatal synapses of normal and Huntington mice.
Dvorzhak, A., Helassa, N., Torok, K., Schmitz, D. and Grantyn, R.
bioRxiv
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30 October 2018
Disease modification in multiple sclerosis by flupirtine - results of a randomized placebo controlled phase II trial.
Dörr, J., Wernecke, K.D., Würfel, J., Bellmann-Strobl, J., Siffrin, V., Sättler, M.B., Simons, M., Linsa, A., Tumani, H. and Paul, F.
Frontiers in Neurology 9
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October 2018
Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit.
Edemann-Callesen, H., Habelt, B., Wieske, F., Jackson, M., Khadka, N., Mattei, D., Bernhardt, N., Heinz, A., Liebetanz, D., Bikson, M., Padberg, F., Hadar, R., Nitsche, N. and Winter, C.
Translational Psychiatry 8
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10 January 2018
Crosstalk between core-multishell nanocarriers for cutaneous drug delivery and antigen-presenting cells of the skin.
Edlich, A., Volz, P., Brodwolf, R., Unbehauen, M., Mundhenk, L., Gruber, A.D., Hedtrich, S., Haag, R., Alexiev, U. and Kleuser, B.
Biomaterials 162
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April 2018
Antiproliferative activity of the combination of doxorubicin/quercetin on MCF7 breast cancer cell line: a combined study using colorimetric assay and synchrotron infrared microspectroscopy.
Elmadany, N., Khalil, E., Vaccari, L., Birarda, G., Yousef, I. and Abu-Dahab, R.
Infrared Physics & Technology 95
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December 2018
A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism.
Fernandes-Rosa, F.L., Daniil, G., Orozco, I.J., Göppner, C., El Zein, R., Jain, V., Boulkroun, S., Jeunemaitre, X., Amar, L., Lefebvre, H., Schwarzmayr, T., Strom, T.M., Jentsch, T.J. and Zennaro, M.C.
Nature Genetics 50
(3): 355-361.
March 2018
Dendrite-specific amplification of weak synaptic input during network activity in vivo.
Ferrarese, L., Jouhanneau, J.S., Remme, M.W.H., Kremkow, J., Katona, G., Rózsa, B., Schreiber, S. and Poulet, J.F.A.
Cell Reports 24
(13): 3455-3465.
25 September 2018
Association of visual impairment in neuromyelitis optica spectrum disorder with visual network reorganization.
Finke, C., Zimmermann, H., Pache, F., Oertel, F.C., Chavarro, V.S., Kramarenko, Y., Bellmann-Strobl, J., Ruprecht, K., Brandt, A.U. and Paul, F.
JAMA Neurology 75
(3): 296-303.
March 2018
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
Franko, A., Rodriguez Camargo, D.C., Böddrich, A., Garg, D., Rodriguez Camargo, A., Rathkolb, B., Janik, D., Aichler, M., Feuchtinger, A., Neff, F., Fuchs, H., Wanker, E.E., Reif, B., Häring, H.U., Peter, A. and Hrabě de Angelis, M.
Scientific Reports 8
(1): 1116.
18 January 2018
FENS Forum 2018 - Neuer Teilnehmer-Rekord.
Friauf, E. and Kettenmann, H.
Neuroforum 24
(4): 297-299.
9 November 2018
Human axial progenitors generate trunk neural crest cells in vitro.
Frith, T.J.R., Granata, I., Wind, M., Stout, E., Thompson, O., Neumann, K., Stavish, D., Heath, P.R., Ortmann, D., Hackland, J.O.S., Anastassiadis, K., Gouti, M., Briscoe, J., Wilson, V., Johnson, S.L., Placzek, M., Guarracino, M.R., Andrews, P.W. and Tsakiridis, A.
eLife 7
: e35786.
10 August 2018
IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies.
Fung, H.Y.J., Birol, M. and Rhoades, E.
Current Opinion in Structural Biology 49
: 36-43.
April 2018
Safety and preliminary efficacy of deep transcranial magnetic stimulation in MS-related fatigue.
Gaede, G., Tiede, M., Lorenz, I., Brandt, A.U., Pfueller, C., Dörr, J., Bellmann-Strobl, J., Piper, S.K., Roth, Y., Zangen, A., Schippling, S. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 5
(1): e423.
1 January 2018
Active contour method for ILM segmentation in ONH volume scans in retinal OCT.
Gawlik, K., Hausser, F., Paul, F., Brandt, A.U. and Kadas, E.M.
Biomedical Optics Express 9
(12): 6497.
1 December 2018
The current role of MRI in differentiating multiple sclerosis from its imaging mimics.
Geraldes, R., Ciccarelli, O., Barkhof, F., De Stefano, N., Enzinger, C., Filippi, M., Hofer, M., Paul, F., Preziosa, P., Rovira, A., DeLuca, G.C., Kappos, L., Yousry, T., Fazekas, F., Frederiksen, J., Gasperini, C., Sastre-Garriga, J., Evangelou, N. and Palace, J.
Nature Reviews Neurology 14
(4): 199-213.
April 2018
Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels.
Giulbudagian, M., Hönzke, S., Bergueiro, J., Işık, D., Schumacher, F., Saeidpour, S., Lohan, S.B., Meinke, M.C., Teutloff, C., Schäfer-Korting, M., Yealland, G., Kleuser, B., Hedtrich, S. and Calderón, M.
Nanoscale 10
(1): 469-479.
7 January 2018
Breaking the barrier - potent anti-inflammatory activity following efficient topical delivery of etanercept using thermoresponsive nanogels.
Giulbudagian, M., Yealland, G., Hönzke, S., Edlich, A., Geisendörfer, B., Kleuser, B., Hedtrich, S. and Calderón, M.
Theranostics 8
(2): 450-463.
1 January 2018
An eicosanoid protects from statin-induced myopathic changes in primary human cells.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
bioRxiv
: 271932.
26 February 2018
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