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The cellular basis of a corollary discharge

Item Type:Article
Title:The cellular basis of a corollary discharge
Creators Name:Poulet, J.F.A. and Hedwig, B.
Abstract:How do animals discriminate self-generated from external stimuli during behavior and prevent desensitization of their sensory pathways? A fundamental concept in neuroscience states that neural signals, termed corollary discharges or efference copies, are forwarded from motor to sensory areas. Neurons mediating these signals have proved difficult to identify. We show that a single, multisegmental interneuron is responsible for the pre- and postsynaptic inhibition of auditory neurons in singing crickets (Gryllus bimaculatus). Therefore, this neuron represents a corollary discharge interneuron that provides a neuronal basis for the central control of sensory responses.
Keywords:Acoustic Stimulation, Action Potentials, Auditory Pathways, Axons, Dendrites, Animal Flight, Invertebrate Ganglia, Interneurons, Motor Neurons, Neural Inhibition, Afferent Neurons, Synapses, Synaptic Transmission, Animal Vocalization, Wing, Animals, Gryllidae
Publisher:American Association for the Advancement of Science
Page Range:518-522
Date:27 January 2006
Official Publication:https://doi.org/10.1126/science.1120847
PubMed:View item in PubMed

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