Akalin, Altuna (BIMSB)

Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A. ORCID: https://orcid.org/0000-0001-7217-3881, Gündüz, I.B. ORCID: https://orcid.org/0000-0003-2641-0916, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Cancers 14 (22): 5604. 15 November 2022

The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L. ORCID: https://orcid.org/0000-0001-7702-5749, Morao, A.K. ORCID: https://orcid.org/0000-0003-2194-8071, Kim, J. ORCID: https://orcid.org/0000-0001-9473-3093, Jimenez, D.S. ORCID: https://orcid.org/0000-0003-0943-9063, Maryn, N. ORCID: https://orcid.org/0000-0002-0975-3354, Bikkasani, K. ORCID: https://orcid.org/0000-0002-4000-1863, Carrozza, M.J., Albritton, S.E. ORCID: https://orcid.org/0000-0001-6093-9560, Kramer, M. ORCID: https://orcid.org/0000-0002-1643-0756, Street, L.A. ORCID: https://orcid.org/0000-0002-5473-6713, Cerimi, K. ORCID: https://orcid.org/0000-0003-0775-3032, Schumann, V.F. ORCID: https://orcid.org/0000-0003-0227-7428, Bahry, E. ORCID: https://orcid.org/0000-0002-6358-2576, Preibisch, S. ORCID: https://orcid.org/0000-0002-0276-494X, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313 and Ercan, S. ORCID: https://orcid.org/0000-0001-7297-1648
Journal of Cell Science 135 (2): jcs258818. January 2022

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. ORCID: https://orcid.org/0000-0002-8499-1387, Rom, A., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Arrey, G., Terne, M., Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Ulitsky, I. ORCID: https://orcid.org/0000-0003-0555-6561 and Chekulaeva, M. ORCID: https://orcid.org/0000-0002-6868-7887
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V. ORCID: https://orcid.org/0000-0002-0077-1935, Berruezo-Llacuna, M., Altwasser, R. ORCID: https://orcid.org/0009-0002-6216-6068, Winkler, W. ORCID: https://orcid.org/0000-0001-8807-9259, Sundaravinayagam, D. ORCID: https://orcid.org/0000-0003-0717-7530, Balasubramanian, S. ORCID: https://orcid.org/0000-0003-1830-5737, Caganova, M. ORCID: https://orcid.org/0000-0002-4576-6574, Graf, R. ORCID: https://orcid.org/0000-0002-5400-9938, Rahjouei, A. ORCID: https://orcid.org/0000-0003-3973-6333, Henke, M.T. ORCID: https://orcid.org/0000-0001-6572-1667, Driesner, M., Keller, L., Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952, Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793
Journal of Experimental Medicine 217 (10): e20200137. 5 October 2020

Nuclear organization in the spinal cord depends on motor neuron lamination orchestrated by catenin and afadin function.
Dewitz, C. ORCID: https://orcid.org/0000-0003-3093-3138, Pimpinella, S., Hackel, P., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Jessell, T.M. and Zampieri, N. ORCID: https://orcid.org/0000-0002-2228-9453
Cell Reports 22 (7): 1681-1694. 13 February 2018

Identifying tumor cells at the single-cell level using machine learning.
Dohmen, J. ORCID: https://orcid.org/0000-0002-7826-3025, Baranovskii, A. ORCID: https://orcid.org/0000-0001-7217-3881, Ronen, J. ORCID: https://orcid.org/0000-0003-3980-6469, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Genome Biology 23 (1): 123. 30 May 2022

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M. ORCID: https://orcid.org/0000-0002-6863-841X, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Brandt, B., Lowenstein, E.D. ORCID: https://orcid.org/0000-0003-3755-0818, Schöwel, V. ORCID: https://orcid.org/0000-0002-5924-3088, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Nature Communications 11 : 6375. 11 December 2020

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E. ORCID: https://orcid.org/0000-0002-7811-3174, Ofenbauer, A. ORCID: https://orcid.org/0000-0003-0379-9105, Bulut, S.I., Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Baytek, G. ORCID: https://orcid.org/0000-0001-9731-9461, Sommermeier, A., Seelk, S. ORCID: https://orcid.org/0000-0002-3525-8859, He, M., Hirsekorn, A., Vucicevic, D. ORCID: https://orcid.org/0000-0002-1162-6709, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Lacadie, S.A. ORCID: https://orcid.org/0000-0002-0893-5340 and Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629
Developmental Cell 46 (5): 611-626. 10 September 2018

VoltRon: a spatial omics analysis platform for multi-resolution and multi-omics integration using image registration.
Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Bahry, E. ORCID: https://orcid.org/0000-0002-6358-2576, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Becher, E., Pascual-Reguant, Anna, Plumbom, I. ORCID: https://orcid.org/0009-0006-3720-3700, Dikmen, H.O., Elezkurtaj, S., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Hauser, A.E., Hocke, A., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Schmidt, D. ORCID: https://orcid.org/0000-0002-8621-9438, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
bioRxiv : 2023.12.15.571667. 15 December 2023

Lymphocyte access to lymphoma is impaired by high endothelial venule regression.
Menzel, L. ORCID: https://orcid.org/0000-0002-3816-6255, Zschummel, M. ORCID: https://orcid.org/0000-0002-4778-8742, Crowley, T. ORCID: https://orcid.org/0000-0002-1404-6005, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Grau, M., Ulbricht, C. ORCID: https://orcid.org/0000-0003-2983-6242, Hauser, A., Siffrin, V. ORCID: https://orcid.org/0000-0002-1532-2868, Bajénoff, M., Acton, S.E., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Lenz, G., Willimsky, G. ORCID: https://orcid.org/0000-0002-9693-948X, Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893 and Rehm, A. ORCID: https://orcid.org/0000-0001-7490-1950
Cell Reports 37 (4): 109878. 26 October 2021

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Cheng, J.Y. ORCID: https://orcid.org/0000-0001-8942-0607, Russo, G., Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X, Szymborska, A. ORCID: https://orcid.org/0000-0003-1741-4106, Zauber, H. ORCID: https://orcid.org/0000-0003-2595-1147, Rudolph, I.M. ORCID: https://orcid.org/0000-0002-3903-0755, Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Haucke, V. ORCID: https://orcid.org/0000-0003-3119-6993, Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Krauss, M., Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Pascual, J.M. and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Cell 175 (1): 239-253. 20 September 2018

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S. ORCID: https://orcid.org/0000-0002-3525-8859, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, He, M., Krause, A. ORCID: https://orcid.org/0000-0001-9515-2477, Vitrinel, B. ORCID: https://orcid.org/0000-0002-5049-6572, Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629
Aging Cell 18 (6): e13012. December 2019

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T. ORCID: https://orcid.org/0000-0002-9075-103X, Meyer, K. ORCID: https://orcid.org/0000-0002-8244-6887, Roske, Y. ORCID: https://orcid.org/0000-0001-6237-388X, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Ishihama, Y., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Nature Communications 15 (1): 3146. 11 April 2024

Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J. ORCID: https://orcid.org/0000-0001-8810-0492, Sundaravinayagam, D. ORCID: https://orcid.org/0000-0003-0717-7530, Blume, A. ORCID: https://orcid.org/0000-0003-3045-8234, Marg, A. ORCID: https://orcid.org/0000-0003-3673-4244, Grunwald, S. ORCID: https://orcid.org/0000-0002-3899-5424, Metzler, E. ORCID: https://orcid.org/0000-0003-1735-6364, Escobar, H. ORCID: https://orcid.org/0000-0002-8128-7845, Müthel, S. ORCID: https://orcid.org/0000-0002-3525-8859, Wang, H. ORCID: https://orcid.org/0000-0003-3720-3859, Wollersheim, T. ORCID: https://orcid.org/0000-0002-3170-0996, Weber-Carstens, S., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Di Virgilio, M. ORCID: https://orcid.org/0000-0001-5189-0793, Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
International Journal of Molecular Sciences 24 (3): 2772. 1 February 2023

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F. ORCID: https://orcid.org/0000-0003-0227-7428, de Castro Cuadrat, R.R. ORCID: https://orcid.org/0000-0001-8289-2599, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Deter, A., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Dohmen, J. ORCID: https://orcid.org/0000-0002-7826-3025, Faxel, M. ORCID: https://orcid.org/0009-0007-4891-1734, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Blume, A. ORCID: https://orcid.org/0000-0003-3045-8234, Freimuth, J. ORCID: https://orcid.org/0000-0002-9259-3696, Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Barke, N. ORCID: https://orcid.org/0009-0004-5862-6628, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Science of the Total Environment 853 : 158931. 20 December 2022

HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K. ORCID: https://orcid.org/0000-0002-5994-4802, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Bulut, S., Tursun, B. ORCID: https://orcid.org/0000-0001-7293-8629 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Nucleic Acids Research : gkz460. 20 June 2019

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Mösbauer, K., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Diag, A., Gottula, L.T., Arsiè, R. ORCID: https://orcid.org/0000-0002-7869-7624, Klironomos, F., Koppstein, D. ORCID: https://orcid.org/0000-0002-8618-7237, Hönzke, K., Ayoub, S. ORCID: https://orcid.org/0000-0001-5043-8922, Buccitelli, C. ORCID: https://orcid.org/0000-0002-2637-2131, Hoffmann, K., Richter, A., Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, Del Giudice, S. ORCID: https://orcid.org/0000-0003-0194-3767, Papies, J., Praktiknjo, S. ORCID: https://orcid.org/0000-0002-0186-5271, Meyer, T.F., Müller, M.A., Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Hocke, A., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Drosten, C. and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
iScience 24 (3): 102151. 19 March 2021

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A., van den Bruck, D., Ciolli Mattioli, C. ORCID: https://orcid.org/0000-0002-8499-1387, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Moreno-Estelles, M., Calviello, L. ORCID: https://orcid.org/0000-0002-5600-0988, Filipchyk, A. ORCID: https://orcid.org/0000-0002-2029-8460, Peguero-Sanchez, E. ORCID: https://orcid.org/0000-0002-8317-5572, Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Merino, E., Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Mazzoni, E.O., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Chekulaeva, M. ORCID: https://orcid.org/0000-0002-6868-7887
Nature Communications 8 (1): 583. 19 September 2017

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Schulz-Beiss, K.W., Patone, G. ORCID: https://orcid.org/0000-0002-7242-0341, Schleussner, N. ORCID: https://orcid.org/0009-0001-3549-5600, Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Hübner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
Blood 133 (13): 1489-1494. 28 March 2019

Alexander, Christiane

Characterization of OPA1 isoforms isolated from mouse tissues.
Akepati, V.R., Mueller, E.C., Otto, A., Strauss, H., Portwich, M. and Alexander, C.
Journal of Neurochemistry 106 (1): 372-383. July 2008

Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy.
Fuhrmann, N., Schimpf, S., Kamenisch, Y., Leo-Kottler, B., Alexander, C., Auburger, G., Zrenner, E., Wissinger, B. and Alavi, M.V.
Molecular Neurodegeneration 5 (1): 25. 14 June 2010

Molekulargenetische Identifizierung von Determinanten der photoparoxysmalen Reaktion.
Lorenz, S.
UNSPECIFIED thesis, UNSPECIFIED. 25 July 2006

Candidate gene analysis of the succinic semialdehyde dehydrogenase gene (ALDH5A1) in patients with idiopathic generalized epilepsy and photosensitivity.
Lorenz, S., Heils, A., Taylor, K.P., Gehrmann, A., Muhle, H., Gresch, M., Becker, T., Tauer, U., Stephani, U. and Sander, T.
Neuroscience Letters 397 (3): 234-239. 24 April 2006

OPA1, the disease gene for autosomal dominant optic atrophy, is specifically expressed in ganglion cells and intrinsic neurons of the retina.
Pesch, U.E.A., Fries, J.E., Bette, S., Kalbacher, H., Wissinger, B., Alexander, C. and Kohler, K.
Investigative Ophthalmology & Visual Science 45 (11): 4217-4225. 1 January 2004

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.
Song, Z., Chen, H., Fiket, M., Alexander, C. and Chan, D.C.
Journal of Cell Biology 178 (5): 749-755. 27 August 2007

Altmüller, Janine (BIMSB/BIH)

Formation of amyloid-like HTTex1 aggregates in neurons, downregulation of synaptic proteins and early mortality of Huntington's disease flies are causally linked.
Ast, A. ORCID: https://orcid.org/0000-0002-2312-1257, Roth, L., Brusendorf, L., Schindler, F. ORCID: https://orcid.org/0000-0002-3320-8284, Ammar, O.W.M. ORCID: https://orcid.org/0009-0003-5341-4434, Berberich, S., Edel, J., Bonsor, M. ORCID: https://orcid.org/0000-0001-5447-084X, Georgii, E., Hänig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Langnick, C., Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Piraud, M., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Petzoldt, A.G. and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
bioRxiv : 2025.02.06.636778. 7 February 2025

In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia.
Bakina, O. ORCID: https://orcid.org/0000-0002-3486-9906, Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Mitic, N. ORCID: https://orcid.org/0000-0003-0141-1293, Vidal, R.O. ORCID: https://orcid.org/0000-0003-4217-2014, Obrusnik, T., Sai, S. ORCID: https://orcid.org/0000-0001-6865-341X, Nolte, C. ORCID: https://orcid.org/0000-0001-5398-3440, Semtner, M. ORCID: https://orcid.org/0000-0001-9379-9023 and Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291
PLoS ONE 19 (7): e0302376. 11 July 2024

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Urzi, A., Vidal, R. ORCID: https://orcid.org/0000-0003-4217-2014, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Kabuss, L., Hube, I., Gazzerro, E. ORCID: https://orcid.org/0000-0003-2428-0302, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693 and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
Cell Stem Cell 26 (2): 172-186. 6 February 2020

Spreading α-synuclein rewires organelle communication and impairs neuron-astrocyte mitochondrial quality control.
Fritsch, Elisabeth ORCID: https://orcid.org/0000-0002-4207-0395, Horvatovic, Kamelija ORCID: https://orcid.org/0000-0002-3424-1326, Santos Otte, Paula ORCID: https://orcid.org/0009-0009-4556-0574, Koudelka, Tomas ORCID: https://orcid.org/0009-0008-2895-6051, Rossius, Jana ORCID: https://orcid.org/0009-0000-6011-9714, Braeuning, Caroline ORCID: https://orcid.org/0009-0007-1439-9920, Breimann, Laura ORCID: https://orcid.org/0000-0001-7702-5749, Piazza, Ilaria ORCID: https://orcid.org/0000-0001-5895-6134 and Birol, Melissa ORCID: https://orcid.org/0000-0003-3397-8446
bioRxiv : 2026.06.19.733342. 23 June 2026

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J. ORCID: https://orcid.org/0000-0002-6432-7104, Muinjonov, B. ORCID: https://orcid.org/0000-0002-9380-8038, Rosiewicz, K.S. ORCID: https://orcid.org/0000-0002-6926-7227, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992, Biese, C., Schiweck, J., Chien, C. ORCID: https://orcid.org/0000-0001-8280-9513, Zocholl, D., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Alisch, M. ORCID: https://orcid.org/0009-0000-8316-6193 and Siffrin, V. ORCID: https://orcid.org/0000-0002-1532-2868
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

VoltRon: a spatial omics analysis platform for multi-resolution and multi-omics integration using image registration.
Manukyan, A. ORCID: https://orcid.org/0000-0002-0441-9517, Bahry, E. ORCID: https://orcid.org/0000-0002-6358-2576, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Becher, E., Pascual-Reguant, Anna, Plumbom, I. ORCID: https://orcid.org/0009-0006-3720-3700, Dikmen, H.O., Elezkurtaj, S., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Hauser, A.E., Hocke, A., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Schmidt, D. ORCID: https://orcid.org/0000-0002-8621-9438, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
bioRxiv : 2023.12.15.571667. 15 December 2023

Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E. ORCID: https://orcid.org/0000-0003-1735-6364, Escobar, H. ORCID: https://orcid.org/0000-0002-8128-7845, Sunaga-Franze, D.Y. ORCID: https://orcid.org/0000-0002-6851-9162, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693, Diecke, S. ORCID: https://orcid.org/0000-0002-5219-5992 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
Biomedicines 10 (5): 1204. 23 May 2022

A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A. ORCID: https://orcid.org/0000-0001-6163-3344, Bakina, O. ORCID: https://orcid.org/0000-0002-3486-9906, Badillo Lisakowski, V. ORCID: https://orcid.org/0000-0001-5906-2589, Olivares-Chauvet, P., Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295, Gotthardt, M. ORCID: https://orcid.org/0000-0003-1788-3172, Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Junker, J.P. ORCID: https://orcid.org/0000-0002-2826-8290
Molecular Systems Biology 19 (2): e11147. 10 February 2023

Rare variants in γ-aminobutyric acid type A receptor genes in rolandic epilepsy and related syndromes.
Reinthaler, E.M., Dejanovic, B., Lal, D., Semtner, M. ORCID: https://orcid.org/0000-0001-9379-9023, Merkler, Y., Reinhold, A., Pittrich, D.A., Hotzy, C., Feucht, M., Steinböck, H., Gruber-Sedlmayr, U., Ronen, G.M., Neophytou, B., Geldner, J., Haberlandt, E., Muhle, H., Ikram, M.A., van Duijn, C.M., Uitterlinden, A.G., Hofman, A., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Kawalia, A., Toliat, M.R., Nürnberg, P., Lerche, H., Nothnagel, M., Thiele, H., Sander, T., Meier, J.C. ORCID: https://orcid.org/0000-0002-2041-8872, Schwarz, G., Neubauer, B.A. and Zimprich, F.
Annals of Neurology 77 (6): 972-986. June 2015

Rare variants in GABA(A) receptor genes in Rolandic epilepsy and related syndromes.
Reinthaler, E.M., Dejanovic, B., Lal, D., Semtner, M. ORCID: https://orcid.org/0000-0001-9379-9023, Merkler, Y., Reinhold, A., Pittrich, D.A., Hotzy, C., Feucht, M., Steinboeck, H., Gruber-Sedlmayr, U., Ronen, G., Neophytou, B., Geldner, J., Haberlandt, E., Muhle, H., Ikram, M.A., van Duijn, CM., Uitterlinden, A.G., Hofman, A., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Kawalia, A., Toliat, M.R., Nuernberg, P., Lerche, H., Nothnagel, M., Thiele, H., Sander, T., Meier, J.C. ORCID: https://orcid.org/0000-0001-5574-3336, Schwarz, G., Neubauer, B.A. and Zimprich, F.
Annals of Neurology 77 (6): 972-986. June 2015

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F. ORCID: https://orcid.org/0000-0003-0227-7428, de Castro Cuadrat, R.R. ORCID: https://orcid.org/0000-0001-8289-2599, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Wurmus, R. ORCID: https://orcid.org/0009-0003-0140-4189, Deter, A., Quedenau, C. ORCID: https://orcid.org/0000-0002-6846-4915, Dohmen, J. ORCID: https://orcid.org/0000-0002-7826-3025, Faxel, M. ORCID: https://orcid.org/0009-0007-4891-1734, Borodina, T. ORCID: https://orcid.org/0000-0002-6978-016X, Blume, A. ORCID: https://orcid.org/0000-0003-3045-8234, Freimuth, J. ORCID: https://orcid.org/0000-0002-9259-3696, Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Barke, N. ORCID: https://orcid.org/0009-0004-5862-6628, Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734 and Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117
Science of the Total Environment 853 : 158931. 20 December 2022

Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration.
Sekulic, Andjela, Herr, Sarah M., Mulfaul, Kelly, Pompös, Inga-Marie ORCID: https://orcid.org/0000-0001-9314-8378, Winkler, Silvia, Dietrich, Carola, Obermayer, Benedikt ORCID: https://orcid.org/0000-0002-9116-630X, Mullins, Robert F., Conrad, Thomas ORCID: https://orcid.org/0000-0001-5618-6295, Zipfel, Peter F., Sennlaub, Florian, Skerka, Christine and Strauß, Olaf
Journal of Neuroinflammation 22 (1): 173. 3 July 2025

Andrade Navarro, Miguel

Aversion to nicotine is regulated by the balanced activity of beta4 and alpha5 nicotinic receptor subunits in the medial habenula.
Frahm, S. ORCID: https://orcid.org/0000-0001-5645-2557, Slimak, M.A. ORCID: https://orcid.org/0000-0003-3203-2309, Ferrarese, L., Santos-Torres, J., Antolin-Fontes, B. ORCID: https://orcid.org/0000-0002-5724-0932, Auer, S., Filkin, S., Pons, S., Fontaine, J.F. ORCID: https://orcid.org/0000-0002-1101-4091, Tsetlin, V., Maskos, U. and Ibanez-Tallon, I.
Neuron 70 (3): 522-535. 12 May 2011

Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains.
Haenig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Atias, N., Taylor, A.K., Mazza, A., Schaefer, M.H., Russ, J. ORCID: https://orcid.org/0000-0001-6550-761X, Riechers, S.P. ORCID: https://orcid.org/0000-0001-6933-9174, Jain, S., Coughlin, M., Fontaine, J.F. ORCID: https://orcid.org/0000-0002-1101-4091, Freibaum, B.D., Brusendorf, L., Zenkner, M., Porras, P. ORCID: https://orcid.org/0000-0002-8429-8793, Stroedicke, M., Schnoegl, S., Arnsburg, K., Boeddrich, A. ORCID: https://orcid.org/0000-0001-9118-050X, Pigazzini, L., Heutink, P., Taylor, J.P., Kirstein, J. ORCID: https://orcid.org/0000-0003-4990-2497, Andrade-Navarro, M.A., Sharan, R. and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Cell Reports 32 (7): 108050. 18 August 2020

Detection of alpha-rod protein repeats using a neural network and application to huntingtin.
Palidwor, G.A., Shcherbinin, S., Huska, M.R. ORCID: https://orcid.org/0000-0002-0912-745X, Rasko, T., Stelzl, U. ORCID: https://orcid.org/0000-0003-2500-3585, Arumughan, A., Foulle, R., Porras, P. ORCID: https://orcid.org/0000-0002-8429-8793, Sanchez-Pulido, L., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630 and Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711
PLoS Computational Biology 5 (3): e1000304. 13 March 2009

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
Petrakis, S., Rasko, T., Russ, J. ORCID: https://orcid.org/0000-0001-6550-761X, Friedrich, R.P., Stroedicke, M., Riechers, S.P. ORCID: https://orcid.org/0000-0001-6933-9174, Muehlenberg, K., Moeller, A., Reinhardt, A., Vinayagam, A., Schaefer, M.H., Boutros, M., Tricoire, H., Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711 and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
PLoS Genetics 8 (8): e1002897. 16 August 2012

Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
Petrakis, S., Schaefer, M.H., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630 and Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711
BioEssays 35 (6): 503-507. June 2013

HIPPIE: integrating protein interaction networks with experiment based quality scores.
Schaefer, M.H., Fontaine, J.F. ORCID: https://orcid.org/0000-0002-1101-4091, Vinayagam, A., Porras, P. ORCID: https://orcid.org/0000-0002-8429-8793, Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630 and Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711
PLoS ONE 7 (2): e31826. 14 February 2012

Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Schaefer, M.H., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630 and Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711
Nucleic Acids Research 40 (10): 4273-4287. 1 May 2012

Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke, M., Bounab, Y., Strempel, N., Klockmeier, K., Yigit, S., Friedrich, R.P., Chaurasia, G., Li, S., Hesse, F. ORCID: https://orcid.org/0000-0002-3320-8284, Riechers, S.P. ORCID: https://orcid.org/0000-0001-6933-9174, Russ, J. ORCID: https://orcid.org/0000-0001-6550-761X, Nicoletti, C., Boeddrich, A. ORCID: https://orcid.org/0000-0001-9118-050X, Wiglenda, T. ORCID: https://orcid.org/0000-0002-8460-9459, Haenig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Schnoegl, S., Fournier, D., Graham, R.K., Hayden, M.R., Sigrist, S., Bates, G.P., Priller, J. ORCID: https://orcid.org/0000-0001-7596-0979, Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711, Futschik, M.E. ORCID: https://orcid.org/0000-0002-6245-8071 and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Genome Research 25 (5): 701-713. May 2015

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
Suratanee, A., Schaefer, M.H., Betts, M.J., Soons, Z., Mannsperger, H., Harder, N., Oswald, M., Gipp, M., Ramminger, E., Marcus, G., Männer, R., Rohr, K., Wanker, E. ORCID: https://orcid.org/0000-0001-8072-1630, Russell, R.B., Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711, Eils, R. and König, R.
PLoS Computational Biology 10 (9): e1003814. 25 September 2014

Development and application of a DNA microarray-based yeast two-hybrid system.
Suter, B., Fontaine, J.F. ORCID: https://orcid.org/0000-0002-1101-4091, Yildirimman, R., Raskó, T., Schaefer, M.H., Rasche, A., Porras, P. ORCID: https://orcid.org/0000-0002-8429-8793, Vázquez-Álvarez, B.M., Russ, J. ORCID: https://orcid.org/0000-0001-6550-761X, Rau, K., Foulle, R., Zenkner, M., Saar, K., Herwig, R., Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711 and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Nucleic Acids Research 41 (3): 1496-507. 1 February 2013

A directed protein interaction network for investigating intracellular signal transduction.
Vinayagam, A., Stelzl, U. ORCID: https://orcid.org/0000-0003-2500-3585, Foulle, R., Plassmann, S., Zenkner, M., Timm, J., Assmus, H.E., Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711 and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Science Signaling 4 (189): rs8. 6 September 2011

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K., Ullrich, F. ORCID: https://orcid.org/0000-0002-1153-2040, Muench, J., Lazarow, K., Lutter, D. ORCID: https://orcid.org/0000-0002-2190-8371, Mah, N. ORCID: https://orcid.org/0000-0002-1240-8076, Andrade-Navarro, M.A. ORCID: https://orcid.org/0000-0001-6650-1711, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Stauber, T. ORCID: https://orcid.org/0000-0003-0727-6109 and Jentsch, T.J. ORCID: https://orcid.org/0000-0002-3509-2553
Science 344 (6184): 634-638. 9 May 2014

Arnold, Susanne

Estrogen suppresses the impact of glucose deprivation on astrocytic calcium levels and signaling independently of the nuclear estrogen receptor.
Arnold, S.
Neurobiology of Disease 20 (1): 82-92. October 2005

The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases.
Kadenbach, B., Arnold, S., Lee, I. and Huettemann, M.
Biochimica et Biophysica Acta - Bioenergetics 1655 : 400-408. 1 January 2004

BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum.
Westphalen, B.C., Wessig, J., Leypoldt, F., Arnold, S. and Methner, A.
Cell Death and Differentiation 12 (3): 304-306. 1 March 2005

Bader, Michael

Reduced nerve injury-induced neuropathic pain in kinin B1 receptor knock-out mice.
Ferreira, J., Beirith, A., Mori, M.A., Araújo, R.C. ORCID: https://orcid.org/0000-0003-0095-4608, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Pesquero, J.B. and Calixto, J.B.
Journal of Neuroscience 25 (9): 2405-2412. 2 March 2005

Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders.
Hadar, R., Edemann-Callesen, H., Reinel, C., Wieske, F., Voget, M., Popova, E. ORCID: https://orcid.org/0000-0002-3043-9650, Sohr, R., Avchalumov, Y., Priller, J. ORCID: https://orcid.org/0000-0001-7596-0979, van Riesen, C., Puls, I., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Winter, C.
Scientific Reports 6 : 39145. 15 December 2016

Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger.
Ifuku, M., Faerber, K., Okuno, Y., Yamakawa, Y., Miyamoto, T., Nolte, C. ORCID: https://orcid.org/0000-0001-5398-3440, Merrino, V.F., Kitada, S., Iwamoto, T., Komuro, I., Wang, B., Cheung, G., Ishikawa, E., Ooboshi, H., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Wada, K., Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Noda, M.
Journal of Neuroscience 27 (48): 13065-13073. 28 November 2007

Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G., Uhlemann, R., Richter, N., Klempin, F. ORCID: https://orcid.org/0000-0003-3171-0497, Wegner, S., Staerck, L., Wolf, S. ORCID: https://orcid.org/0000-0003-0922-8418, Uckert, W., Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291, Endres, M. and Gertz, K.
Acta Neuropathologica 135 (4): 551. April 2018

Exon skipping in a Dysf-missense mutant mouse model.
Malcher, J., Heidt, L., Goyenvalle, A., Escobar, H. ORCID: https://orcid.org/0000-0002-8128-7845, Marg, A. ORCID: https://orcid.org/0000-0003-3673-4244, Beley, C., Benchaouir, R., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, García, L. and Schöwel, V. ORCID: https://orcid.org/0000-0002-5924-3088
Molecular Therapy - Nucleic Acids 13 : 198-207. 7 December 2018

Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.
Schleifenbaum, J. ORCID: https://orcid.org/0000-0002-3195-1517, Kassmann, M. ORCID: https://orcid.org/0000-0002-4785-6530, Szijártó, I.A. ORCID: https://orcid.org/0000-0002-0796-9450, Hercule, H.C., Tano, J.Y. ORCID: https://orcid.org/0000-0001-6351-5907, Weinert, S. ORCID: https://orcid.org/0000-0003-3036-1440, Heidenreich, M., Pathan, A.R., Anistan, Y.M., Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Rusch, N.J., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Jentsch, T.J. ORCID: https://orcid.org/0000-0002-3509-2553 and Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934
Circulation Research 115 (2): 263-272. 7 July 2014

Roles of the kallikrein/kinin system in the adaptive immune system.
Schulze-Topphoff, U., Prat, A., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Zipp, F. ORCID: https://orcid.org/0000-0002-1231-1928 and Aktas, O. ORCID: https://orcid.org/0000-0002-2020-9210
International Immunopharmacology 8 (2): 155-160. February 2008

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system.
Schulze-Topphoff, U., Prat, A., Prozorovski, T., Siffrin, V. ORCID: https://orcid.org/0000-0002-1532-2868, Paterka, M., Herz, J., Bendix, I. ORCID: https://orcid.org/0000-0002-9751-3640, Ifergan, I., Schadock, I., Mori, M.A., Van Horssen, J., Schroeter, F., Smorodchenko, A., Han, M.H., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Steinman, L., Aktas, O. ORCID: https://orcid.org/0000-0002-2020-9210 and Zipp, F. ORCID: https://orcid.org/0000-0002-1231-1928
Nature Medicine 15 (7): 788-793. July 2009

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Yalcin, F. ORCID: https://orcid.org/0000-0001-6325-9018, Haneke, H. ORCID: https://orcid.org/0009-0004-0033-9984, Efe, I.E. ORCID: https://orcid.org/0000-0002-4232-3305, Kuhrt, L.D. ORCID: https://orcid.org/0000-0001-7157-6988, Motta, E. ORCID: https://orcid.org/0000-0003-2526-7994, Nickl, B. ORCID: https://orcid.org/0000-0002-1998-8157, Flüh, C., Synowitz, M., Dzaye, O., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291
Acta Neuropathologica Communications 12 (1): 50. 2 April 2024

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting.
Zanders, L. ORCID: https://orcid.org/0000-0003-0488-6243, Kny, M. ORCID: https://orcid.org/0000-0001-7132-8079, Hahn, A., Schmidt, S., Wundersitz, S., Todiras, M. ORCID: https://orcid.org/0000-0002-9373-4753, Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Bandyopadhyay, A., Wollersheim, T., Kaderali, L., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Weber-Carstens, S. and Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 13 (1): 713-727. February 2021

Discovering the mechanisms underlying serotonin (5-HT)2A and 5-HT2C receptor regulation following nicotine withdrawal in rats.
Zaniewska, M. ORCID: https://orcid.org/0000-0001-9716-6661, Alenina, N. ORCID: https://orcid.org/0000-0002-6071-5433, Wydra, K., Fröhler, S. ORCID: https://orcid.org/0000-0001-8000-2927, Kuśmider, M., McCreary, A.C., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Filip, M.
Journal of Neurochemistry 134 (4): 704-716. August 2015

Behlke, Joachim

Self-association of adrenodoxin studied by using analytical ultracentrifugation.
Behlke, J., Ristau, O., Mueller, E.C., Hannemann, F. and Bernhardt, R.
Biophysical Chemistry 125 (1): 159-165. January 2007

Besser, Daniel

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R., Sternjak, A., Wend, P., Momma, S., Campos, B., Herrmann, I.M., Graf, D., Mitsiadis, T., Herold-Mende, C., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Synowitz, M., Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Paul, F.E. ORCID: https://orcid.org/0000-0001-5181-3122, Cheret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Zurborg, S., Feinberg, K., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Schulz, H. ORCID: https://orcid.org/0000-0002-0226-964X, Peles, E., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J. ORCID: https://orcid.org/0000-0002-7027-0298, Xie, G. ORCID: https://orcid.org/0000-0002-8286-2987, Singh, M. ORCID: https://orcid.org/0000-0002-8626-5418, Ghanbarian, A.T., Raskó, T., Szvetnik, A., Cai, H., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Prigione, A. ORCID: https://orcid.org/0000-0001-9457-1952, Fuchs, N.V. ORCID: https://orcid.org/0000-0003-4175-0740, Schumann, G.G., Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Lorincz, M.C., Ivics, Z. ORCID: https://orcid.org/0000-0002-7803-6658, Hurst, L.D. and Izsvák, Z. ORCID: https://orcid.org/0000-0002-2053-2384
Nature 516 (7531): 405-409. 18 December 2014

Beule, Dieter (MDC/BIH)

Disrupting TSLP-TSLP receptor interactions via putative small molecule inhibitors yields a novel and efficient treatment option for atopic diseases.
Adhikary, P.P. ORCID: https://orcid.org/0000-0002-3755-0810, Idowu, T. ORCID: https://orcid.org/0000-0003-1583-8562, Tan, Z., Hoang, C., Shanta, S., Dumbani, M., Mappalakayil, L. ORCID: https://orcid.org/0009-0009-7418-1215, Awasthi, B. ORCID: https://orcid.org/0000-0002-2636-510X, Bermudez, M. ORCID: https://orcid.org/0000-0002-7421-3282, Weiner, J. ORCID: https://orcid.org/0000-0003-1438-7819, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Wolber, G., Page, B.D. ORCID: https://orcid.org/0000-0002-2101-1329 and Hedtrich, S. ORCID: https://orcid.org/0000-0001-6770-3657
EMBO Molecular Medicine 16 (7): 1630-1656. 15 July 2024

Formation of amyloid-like HTTex1 aggregates in neurons, downregulation of synaptic proteins and early mortality of Huntington's disease flies are causally linked.
Ast, A. ORCID: https://orcid.org/0000-0002-2312-1257, Roth, L., Brusendorf, L., Schindler, F. ORCID: https://orcid.org/0000-0002-3320-8284, Ammar, O.W.M. ORCID: https://orcid.org/0009-0003-5341-4434, Berberich, S., Edel, J., Bonsor, M. ORCID: https://orcid.org/0000-0001-5447-084X, Georgii, E., Hänig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Langnick, C., Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Piraud, M., Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Petzoldt, A.G. and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
bioRxiv : 2025.02.06.636778. 7 February 2025

The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A. ORCID: https://orcid.org/0000-0001-9118-050X, Babila, J.T., Wiglenda, T. ORCID: https://orcid.org/0000-0002-8460-9459, Diez, L. ORCID: https://orcid.org/0000-0003-3101-0191, Jacob, M., Nietfeld, W., Huska, M.R. ORCID: https://orcid.org/0000-0002-0912-745X, Haenig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Groenke, N. ORCID: https://orcid.org/0000-0002-6927-3774, Buntru, A., Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Meier, J.C. ORCID: https://orcid.org/0000-0001-5574-3336, Vannoni, E., Erck, C., Friedrich, B., Martens, H., Neuendorf, N., Schnoegl, S., Wolfer, D.P., Loos, M., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Andrade-Navarro, M.A. and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Cell Chemical Biology 26 (1): 109-120. 17 January 2019

A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A. ORCID: https://orcid.org/0000-0001-9118-050X, Haenig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Neuendorf, N., Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Schleumann, P., Bayraktaroğlu, I., Richter, M. ORCID: https://orcid.org/0000-0002-5339-0781, Molenda, C.M. ORCID: https://orcid.org/0000-0003-0771-405X, Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Zenkner, M., Schnoegl, S., Suenkel, C. ORCID: https://orcid.org/0000-0002-5326-6043, Schneider, L.S., Rybak-Wolf, A. ORCID: https://orcid.org/0000-0002-1192-5290, Kochnowsky, B., Byrne, L.M., Wild, E.J., Nielsen, J.E., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Peters, O. ORCID: https://orcid.org/0000-0003-0568-2998, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Genome Medicine 15 (1): 50. 20 July 2023

let-7 microRNAs regulate microglial function and suppress glioma growth through Toll-like receptor 7.
Buonfiglioli, A. ORCID: https://orcid.org/0000-0002-5550-9360, Efe, I.E. ORCID: https://orcid.org/0000-0002-4232-3305, Guneykaya, D., Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Huang, Y. ORCID: https://orcid.org/0000-0001-9600-1195, Orlowski, E., Krüger, C., Deisz, R.A., Markovic, D., Flüh, C., Newman, A.G. ORCID: https://orcid.org/0000-0002-0222-9162, Schneider, U.C., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Wolf, S.A. ORCID: https://orcid.org/0000-0003-0922-8418, Dzaye, O., Gutmann, D.H. ORCID: https://orcid.org/0000-0002-3127-5045, Semtner, M. ORCID: https://orcid.org/0000-0001-9379-9023, Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Lehnardt, S.
Cell Reports 29 (11): 3460-3471. 10 December 2019

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M. ORCID: https://orcid.org/0000-0002-1663-2075, Klinger, B. ORCID: https://orcid.org/0000-0003-0242-1506, Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, Toedling, J. ORCID: https://orcid.org/0000-0003-1471-1295, Blanc, E. ORCID: https://orcid.org/0000-0002-4369-0254, Messerschmidt, C. ORCID: https://orcid.org/0000-0001-8632-656X, Nadler-Holly, M., Ziehm, M. ORCID: https://orcid.org/0000-0001-7074-4054, Sieber, A. ORCID: https://orcid.org/0000-0001-6588-8547, Hertwig, F. ORCID: https://orcid.org/0000-0003-4784-6516, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Eggert, A., Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Blüthgen, N. ORCID: https://orcid.org/0000-0002-0171-7447
PLoS Computational Biology 17 (11): e1009515. 4 November 2021

Extracellular matrix remodeling in atopic dermatitis harnesses the onset of an asthmatic phenotype and is a potential contributor to the atopic march.
Graff, P. ORCID: https://orcid.org/0000-0002-8819-0181, Woerz, D. ORCID: https://orcid.org/0009-0009-9419-0100, Wilzopolski, J. ORCID: https://orcid.org/0000-0002-6626-4821, Voss, A. ORCID: https://orcid.org/0000-0003-4398-8322, Sarrazin, J. ORCID: https://orcid.org/0009-0002-9875-411X, Blimkie, T.M. ORCID: https://orcid.org/0000-0001-8778-8627, Weiner, J. ORCID: https://orcid.org/0000-0003-1438-7819, Kershaw, O. ORCID: https://orcid.org/0000-0002-3686-9993, Panwar, P. ORCID: https://orcid.org/0009-0002-0574-0318, Hackett, T. ORCID: https://orcid.org/0000-0001-7134-3287, Lau, S. ORCID: https://orcid.org/0000-0002-5189-4265, Brömme, D. ORCID: https://orcid.org/0000-0003-0517-5224, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Lee, Y.A. ORCID: https://orcid.org/0000-0002-1817-9163, Hancock, R.E.W. ORCID: https://orcid.org/0000-0001-5989-8503, Gruber, A.D. ORCID: https://orcid.org/0000-0002-4502-0393, Bäumer, W. ORCID: https://orcid.org/0000-0002-4346-5911 and Hedtrich, S. ORCID: https://orcid.org/0000-0001-6770-3657
Journal of Investigative Dermatology 144 (5): 1010-1021. May 2024

CD4(+) T cell calibration of antigen-presenting cells optimizes antiviral CD8(+) T cell immunity.
Gressier, E. ORCID: https://orcid.org/0000-0003-0517-1610, Schulte-Schrepping, J. ORCID: https://orcid.org/0000-0001-7333-8924, Petrov, L., Brumhard, S., Stubbemann, P., Hiller, A., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Spitzer, J. ORCID: https://orcid.org/0000-0001-9696-2092, Kostevc, T., Whitney, P.G., Bachem, A., Odainic, A. ORCID: https://orcid.org/0000-0002-2806-6904, van de Sandt, C. ORCID: https://orcid.org/0000-0002-4155-7433, Nguyen, T.H.O. ORCID: https://orcid.org/0000-0002-9294-7693, Ashhurst, T. ORCID: https://orcid.org/0000-0001-7269-7773, Wilson, K. ORCID: https://orcid.org/0000-0003-2023-7964, Oates, C.V.L., Gearing, L.J. ORCID: https://orcid.org/0000-0003-3508-3056, Meischel, T. ORCID: https://orcid.org/0000-0002-0911-6574, Hochheiser, K., Greyer, M., Clarke, M., Kreutzenbeck, M., Gabriel, S.S. ORCID: https://orcid.org/0000-0002-6359-485X, Kastenmüller, W. ORCID: https://orcid.org/0000-0002-3835-1485, Kurts, C., Londrigan, S.L. ORCID: https://orcid.org/0000-0003-0989-4971, Kallies, A. ORCID: https://orcid.org/0000-0002-6312-6968, Kedzierska, K. ORCID: https://orcid.org/0000-0001-6141-335X, Hertzog, P.J., Latz, E. ORCID: https://orcid.org/0000-0003-1488-5666, Chen, Y.C.E., Radford, K.J. ORCID: https://orcid.org/0000-0001-6512-6323, Chopin, M., Schroeder, J., Kurth, Fl. ORCID: https://orcid.org/0000-0002-3807-473X, Gebhardt, T. ORCID: https://orcid.org/0000-0002-3768-9468, Sander, L.E. ORCID: https://orcid.org/0000-0002-0476-9947, Sawitzki, B., Schultze, J.L., Schmidt, S.V. and Bedoui, S. ORCID: https://orcid.org/0000-0002-7443-0543
Nature Immunology 24 (6): 979-990. June 2023

Transcriptional and translational differences of microglia from male and female brains.
Guneykaya, D. ORCID: https://orcid.org/0000-0001-5723-0737, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Perez Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Haage, V. ORCID: https://orcid.org/0000-0001-7569-8421, Wojtas, B., Meyer, N. ORCID: https://orcid.org/0000-0002-8377-097X, Maricos, M. ORCID: https://orcid.org/0000-0002-3873-6887, Jordan, P., Buonfiglioli, A. ORCID: https://orcid.org/0000-0002-5550-9360, Gielniewski, B., Ochocka, N., Cömert, C., Friedrich, C. ORCID: https://orcid.org/0000-0002-5586-1989, Suarez Artiles, L. ORCID: https://orcid.org/0000-0001-7991-5446, Kaminska, B., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Wolf, S.A. ORCID: https://orcid.org/0000-0003-0922-8418
Cell Reports 24 (10): 2773-2783. 4 September 2018

Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke, K., Obermayer, B. ORCID: https://orcid.org/0000-0002-9116-630X, Mache, C., Fathykova, D., Kessler, M., Dökel, S., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Baumgardt, M., Löwa, A. ORCID: https://orcid.org/0000-0002-5551-731X, Hoffmann, K., Graff, P., Schulze, J., Mieth, M., Hellwig, K., Demir, Z., Biere, B., Brunotte, L., Mecate-Zambrano, A., Bushe, J., Dohmen, M. ORCID: https://orcid.org/0000-0002-4447-0579, Hinze, C. ORCID: https://orcid.org/0000-0003-2526-1621, Elezkurtaj, S., Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142, Busch, J., Klauschen, F., Horst, D., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Radke, J., Heppner, F., Corman, V.M., Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Müller, M.A., Goffinet, C., Mothes, R., Pascual-Reguant, A., Hauser, A.E., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Ludwig, S., Suttorp, N., Witzenrath, M., Gruber, A.D., Drosten, C., Sander, L.E., Wolff, T., Hippenstiel, S. and Hocke, A.C.
European Respiratory Journal 60 (6): 2102725. 1 December 2022

Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L. ORCID: https://orcid.org/0000-0002-7359-0318, Krupp, F. ORCID: https://orcid.org/0000-0002-0402-8647, Harnett, D. ORCID: https://orcid.org/0000-0002-9190-128X, Turko, P., Ambrozkiewicz, M.C. ORCID: https://orcid.org/0000-0001-5225-5230, Sprink, T. ORCID: https://orcid.org/0000-0002-0760-6828, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Günnigmann, M., Zinnall, U. ORCID: https://orcid.org/0000-0002-0782-7751, Vieira-Vieira, C.H. ORCID: https://orcid.org/0000-0001-5443-4507, Schaub, T. ORCID: https://orcid.org/0000-0003-0790-5040, Münster-Wandowski, A., Bürger, J., Borisova, E., Yamamoto, H., Rasin, M.R., Ohler, U. ORCID: https://orcid.org/0000-0002-0881-3116, Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Mielke, T., Tarabykin, V., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Kramer, G., Vida, I., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Spahn, C.M.T.
Molecular Cell 81 (2): 304-322. 21 January 2021

Microglia undergo molecular and functional adaptations to dark and light phases in male laboratory mice.
Mattei, D. ORCID: https://orcid.org/0000-0001-6221-9321, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Hammer, J., Ugursu, B. ORCID: https://orcid.org/0000-0002-2488-4141, Schalbetter, S., Richetto, J., Weber-Stadlbauer, U., Mueller, F., Scarborough, J., Wolf, S.A. ORCID: https://orcid.org/0000-0003-0922-8418, Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291, Wollscheid, B., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632 and Meyer, U. ORCID: https://orcid.org/0000-0001-7244-0345
Brain Behavior and Immunity 210 : 571-583. August 2024

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Mattei, D. ORCID: https://orcid.org/0000-0001-6221-9321, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Ferrai, C. ORCID: https://orcid.org/0000-0002-8088-2757, Jordan, P., Guneykaya, D. ORCID: https://orcid.org/0000-0001-5723-0737, Buonfiglioli, A. ORCID: https://orcid.org/0000-0002-5550-9360, Schaafsma, W., Przanowski, P., Deuther-Conrad, W., Brust, P., Hesse, S., Patt, M., Sabri, O., Ross, T.L., Eggen, B.J.L., Boddeke, E.W.G.M., Kaminska, B., Beule, D. ORCID: https://orcid.org/0000-0002-3284-0632, Pombo, A. ORCID: https://orcid.org/0000-0002-7493-6288, Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Wolf, S.A. ORCID: https://orcid.org/0000-0003-0922-8418
Translational Psychiatry 7 (5): e1120. 9 May 2017

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Mösbauer, K., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Diag, A., Gottula, L.T., Arsiè, R. ORCID: https://orcid.org/0000-0002-7869-7624, Klironomos, F., Koppstein, D. ORCID: https://orcid.org/0000-0002-8618-7237, Hönzke, K., Ayoub, S. ORCID: https://orcid.org/0000-0001-5043-8922, Buccitelli, C. ORCID: https://orcid.org/0000-0002-2637-2131, Hoffmann, K., Richter, A., Legnini, I. ORCID: https://orcid.org/0000-0002-8984-5215, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Mari, T. ORCID: https://orcid.org/0000-0001-6011-9386, Del Giudice, S. ORCID: https://orcid.org/0000-0003-0194-3767, Papies, J., Praktiknjo, S. ORCID: https://orcid.org/0000-0002-0186-5271, Meyer, T.F., Müller, M.A., Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Hocke, A., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332, Drosten, C. and Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734
iScience 24 (3): 102151. 19 March 2021

Bimmler, Marion

Agonistic autoantibodies to the alpha(1)-adrenergic receptor and the beta(2)-adrenergic receptor in Alzheimer's and vascular dementia.
Karczewski, P., Hempel, P., Kunze, R. and Bimmler, M.
Scandinavian Journal of Immunology 75 (5): 524-530. May 2012

Cerebral blood volume estimation by ferumoxytol-enhanced steady-state MRI at 9.4 T reveals microvascular impact of α(1)-adrenergic receptor antibodies.
Pohlmann, A. ORCID: https://orcid.org/0000-0002-8572-2568, Karczewski, P., Ku, M.C. ORCID: https://orcid.org/0000-0003-0963-2461, Dieringer, B., Waiczies, H. ORCID: https://orcid.org/0000-0001-6651-4790, Wisbrun, N., Kox, S., Palatnik, I., Reimann, H.M. ORCID: https://orcid.org/0000-0003-1053-9256, Eichhorn, C., Waiczies, S. ORCID: https://orcid.org/0000-0002-9916-9572, Hempel, P., Lemke, B., Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527 and Bimmler, M.
NMR in Biomedicine 27 (9): 1085-1093. September 2014

Birchmeier, Walter

Met, metastasis, motility and more.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R., Sternjak, A., Wend, P., Momma, S., Campos, B., Herrmann, I.M., Graf, D., Mitsiadis, T., Herold-Mende, C., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Synowitz, M., Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

c-Met is essential for wound healing in the skin.
Chmielowiec, J., Borowiak, M. ORCID: https://orcid.org/0000-0002-5829-1213, Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Stradal, T., Munz, B., Werner, S., Wehland, J., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

Targeting MET in cancer: rationale and progress.
Gherardi, E., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T., Stein, S., Qi, J., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Nave, K.A., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S., Rosario, M., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Advances in Cancer Research 106 : 53-89. 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Paul, F.E. ORCID: https://orcid.org/0000-0001-5181-3122, Cheret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Zurborg, S., Feinberg, K., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Schulz, H. ORCID: https://orcid.org/0000-0002-0226-964X, Peles, E., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J., Vogel, R., Brinkmann, V., Erdmann, B., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Journal of Cell Biology 148 (3): 567-578. 7 February 2000

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.
Rosario, M., Schuster, S., Juettner, R. ORCID: https://orcid.org/0000-0003-3565-0698, Parthasarathy, S., Tarabykin, V. and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Genes & Development 26 (15): 1743-1757. 1 August 2012

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E. ORCID: https://orcid.org/0000-0003-3055-0495, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Cheret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Walcher, J., Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Wulf-Goldenberg, A., Hoelper, S., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Krüger, M., Rajewsky, K. ORCID: https://orcid.org/0000-0002-6633-6370, Meijer, D., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 28 (3): 290-303. 1 February 2014

Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: comparative analysis using six species of bathyergidae.
Smith, E.S.J. ORCID: https://orcid.org/0000-0002-2699-1979, Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Grigoryan, T., Park, T.J., Bennett, N.C. and Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352
Journal of Comparative Neurology 520 (12): 2785-2803. 15 August 2012

A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl, U. ORCID: https://orcid.org/0000-0003-2500-3585, Worm, U., Lalowski, M., Haenig, C. ORCID: https://orcid.org/0000-0003-1973-7646, Brembeck, F.H., Goehler, H., Stroedicke, M., Zenkner, M., Schoenherr, A., Koeppen, S., Timm, J., Mintzlaff, S., Abraham, C., Bock, N., Kietzmann, S., Goedde, A., Toksoez, E., Droege, A., Krobitsch, S., Korn, B., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Lehrach, H. and Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630
Cell 122 (6): 957-968. 23 September 2005

Birchmeier-Kohler, Carmen

Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin.
Adameyko, I., Lallemend, F., Aquino, J.B., Pereira, J.A., Topilko, P., Mueller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Fritz, N., Beljajeva, A., Mochii, M., Liste, I., Usoskin, D., Suter, U., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Ernfors, P.
Cell 139 (2): 366-379. 16 October 2009

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest.
Adameyko, I., Lallemend, F., Furlan, A., Zinin, N., Aranda, S., Kitambi, S.S., Blanchart, A., Favaro, R., Nicolis, S., Luebke, M., Mueller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Suter, U., Zaitoun, I., Takahashi, Y. and Ernfors, P.
Development 139 (2): 397-410. 15 January 2012

Cell fixation and preservation for droplet-based single-cell transcriptomics.
Alles, J. ORCID: https://orcid.org/0000-0003-0681-0410, Karaiskos, N. ORCID: https://orcid.org/0000-0001-7771-3947, Praktiknjo, S.D. ORCID: https://orcid.org/0000-0002-0186-5271, Grosswendt, S. ORCID: https://orcid.org/0000-0001-7722-2937, Wahle, P. ORCID: https://orcid.org/0000-0002-4728-806X, Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Ayoub, S. ORCID: https://orcid.org/0000-0001-5043-8922, Schreyer, L., Boltengagen, A. ORCID: https://orcid.org/0000-0002-8356-9766, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Zinzen, R. ORCID: https://orcid.org/0000-0002-8638-5102, Kocks, C. ORCID: https://orcid.org/0000-0003-1749-3334 and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
BMC Biology 15 (1): 44. 19 May 2017

Touch receptor-derived sensory information alleviates acute pain signaling and fine-tunes nociceptive reflex coordination.
Arcourt, A., Gorham, L., Dhandapani, R., Prato, V., Taberner, F.J., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Gangadharan, V., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Heppenstall, P.A. and Lechner, S.G. ORCID: https://orcid.org/0000-0001-9402-9127
Neuron 93 (1): 179-193. 4 January 2017

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.
Atanasoski, S., Scherer, S.S., Sirkowski, E., Leone, D., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Suter, U.
Journal of Neuroscience 26 (7): 2124-2131. 15 February 2006

The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity.
Baek, J.H., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Zenke, M. and Hieronymus, T.
Journal of Immunology 189 (4): 1699-1707. 15 August 2012

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.
Bartus, K., Galino, J., James, N.D., Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X, Dawes, J.M., Fricker, F.R., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, McMahon, S.B., Ramer, M.S., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Bennett, D.L.H. and Bradbury, E.J.
Brain 139 (Pt 5): 1394-1416. May 2016

Development and more.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Seminars in Cell & Developmental Biology 21 (8): 812-813. October 2010

A fresh breeze from the ivory tower.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Current Opinion in Cell Biology 21 (6): 725-726. December 2009

ErbB receptors and the development of the nervous system.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Experimental Cell Research 315 (4): 611-618. 15 February 2009

Genes that control cell migration during mouse development: from molecules to organisms.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
In: Cell Motility: From Molecules to Organisms. Wiley, 317-330. ISBN 978-0-470-84872-2 29 January 2004

Met, metastasis, motility and more.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003

Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Nave, K.A.
Glia 56 (14): 1491-1497. 1 November 2008

The two faces of MyoD: repressor and activator of gene expression during myogenesis.
Birchmeier, Carmen ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 39 (21-22): 1269-1270. 1 November 2025

Regulation of developmental tempo in different vertebrate species.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Cell Stem Cell 30 (7): 907-908. 6 July 2023

Preface.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Current Topics in Developmental Biology 97 : xi-xii. 2011

Neuregulin/ErbB signaling in developmental myelin formation and nerve repair.
Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Bennett, D.L.H.
Current Topics in Developmental Biology 116 : 45-64. 2016

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud.
Bladt, F., Riethmacher, D., Isenmann, S., Aguzzi, A. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Nature 376 (6543): 768-771. 31 August 1995

Molecular characterization of the intact mouse muscle spindle using a multi-omics approach.
Bornstein, B., Heinemann-Yerushalmi, L., Krief, S., Adler, R., Dassa, B., Leshkowitz, D., Kim, M.C. ORCID: https://orcid.org/0000-0002-6863-841X, Bewick, G., Banks, R.W. ORCID: https://orcid.org/0000-0003-1614-6488 and Zelzer, E. ORCID: https://orcid.org/0000-0002-1584-6602
eLife 12 : e81843. 6 February 2023

Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Brinkmann, B.G., Agarwal, A., Sereda, M.W., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Mueller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Stassart, R.M., Nawaz, S., Humml, C., Velanac, V., Radyushkin, K., Goebbels, S., Fischer, T.M., Franklin, R.J., Lai, C., Ehrenreich, H., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Schwab, M.H. and Nave, K.A.
Neuron 59 (4): 581-595. 28 August 2008

Transgenic and knock-out animals.
Britsch, S. ORCID: https://orcid.org/0000-0003-4379-3322
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1900-1903. ISBN 3-540-44244-8 2006

Tiermodelle in der biomedizinischen Forschung.
Britsch, S. ORCID: https://orcid.org/0000-0003-4379-3322, Strehle, M. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
In: Grundlagen der Molekularen Medizin. Molekulare Medizin . Springer, Berlin [u.a.], 299-339. ISBN 3-540-43207-8 1 January 2003

A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord.
Broehl, D., Strehle, M., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Hori, K., Bormuth, I., Nave, K.A., Mueller, T. ORCID: https://orcid.org/0000-0001-8096-1853 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Developmental Biology 322 (2): 381-393. 15 October 2008

Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on notch signals.
Broehl, D., Vasyutina, E., Czajkowski, M.T. ORCID: https://orcid.org/0000-0002-0122-1943, Griger, J. ORCID: https://orcid.org/0000-0001-8666-3371, Rassek, C., Rahn, H.P. ORCID: https://orcid.org/0000-0002-5233-3937, Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Developmental Cell 23 (3): 469-481. 11 September 2012

Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3.
Cadot, B., Gache, V., Vasyutina, E., Falcone, S., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Gomes, E.R.
EMBO Reports 13 (8): 741-749. 1 August 2012

Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4.
Caubit, X., Lye, C.M., Martin, E., Core, N., Long, D.A., Vola, C., Jenkins, D., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Skaer, H., Woolf, A.S. and Fasano, L.
Development 135 (19): 3301-3310. October 2008

Sustained MAPK/ERK activation in adult Schwann cells impairs nerve repair.
Cervellini, I. ORCID: https://orcid.org/0000-0002-0078-1586, Galino, J., Zhu, N., Allen, S. ORCID: https://orcid.org/0000-0001-8652-6721, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Bennett, D.L. ORCID: https://orcid.org/0000-0002-7996-2696
Journal of Neuroscience 38 (3): 679-690. 17 January 2018

Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.
Chaimowicz, C. ORCID: https://orcid.org/0000-0002-5998-7482, Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Chéret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Zampieri, N. ORCID: https://orcid.org/0000-0002-2228-9453, Fortin, G. ORCID: https://orcid.org/0000-0002-2123-8603, Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Development 146 (17): dev174045. 6 September 2019

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.
Cheret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Willem, M., Fricker, F.R., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Wulf-Goldenberg, A., Tahirovic, S., Nave, K.A., Saftig, P., Haass, C., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Bennett, D.L. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
EMBO Journal 32 (14): 2015-2028. 17 July 2013

c-Met is essential for wound healing in the skin.
Chmielowiec, J., Borowiak, M. ORCID: https://orcid.org/0000-0002-5829-1213, Morkel, M. ORCID: https://orcid.org/0000-0002-2553-9999, Stradal, T., Munz, B., Werner, S., Wehland, J., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

A validated regulatory network for Th17 cell specification.
Ciofani, M., Madar, A., Galan, C., Sellars, M., Mace, K., Pauli, F., Agarwal, A., Huang, W., Parkurst, C.N., Muratet, M., Newberry, K.M., Meadows, S., Greenfield, A., Yang, Y., Jain, P., Kirigin, F.K., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Wagner, E.F., Murphy, K.M., Myers, R.M., Bonneau, R. and Littman, D.R.
Cell 151 (2): 289-303. 12 October 2012

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C. ORCID: https://orcid.org/0000-0002-8499-1387, Rom, A., Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Imami, K. ORCID: https://orcid.org/0000-0002-7451-4982, Arrey, G., Terne, M., Woehler, A. ORCID: https://orcid.org/0000-0001-5157-9313, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Ulitsky, I. ORCID: https://orcid.org/0000-0003-0555-6561 and Chekulaeva, M. ORCID: https://orcid.org/0000-0002-6868-7887
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Genetic identification of medullary neurons underlying congenital hypoventilation.
Cui, K. ORCID: https://orcid.org/0009-0006-4453-3601, Xia, Y., Patnaik, A. ORCID: https://orcid.org/0000-0002-7141-8573, Salivara, A., Lowenstein, E.D. ORCID: https://orcid.org/0000-0003-3755-0818, Isik, E.G. ORCID: https://orcid.org/0009-0007-9951-1925, Knorz, A.L. ORCID: https://orcid.org/0000-0002-7924-0394, Airaghi, L., Crotti, M. ORCID: https://orcid.org/0009-0003-2834-2969, Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Meng, F., Schmitz, D. ORCID: https://orcid.org/0000-0003-2741-5241, Studer, M. ORCID: https://orcid.org/0000-0001-7105-2957, Rijli, F.M. ORCID: https://orcid.org/0000-0003-0515-0182, Nothwang, H.G., Rost, B.R. ORCID: https://orcid.org/0000-0003-1906-0081, Strauß, U. ORCID: https://orcid.org/0000-0002-1534-6624 and Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X
Science Advances 10 (25): eadj0720. 21 June 2024

Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle.
Czajkowski, M.T. ORCID: https://orcid.org/0000-0002-0122-1943, Rassek, C., Lenhard, D., Bröhl, D. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Developmental Biology 395 (2): 307-3016. 15 November 2014

Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways.
D'Autreaux, F., Coppola, E., Hirsch, M.R., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Brunet, J.F.
Proceedings of the National Academy of Sciences of the United States of America 108 (50): 20018-20023. 13 December 2011

A medullary centre for lapping in mice.
Dempsey, B., Sungeelee, S., Bokiniec, P. ORCID: https://orcid.org/0000-0002-3139-4765, Chettouh, Z., Diem, S. ORCID: https://orcid.org/0000-0001-6763-8752, Autran, S., Harrell, E.R., Poulet, J.F.A. ORCID: https://orcid.org/0000-0003-0296-5415, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Carey, H., Genovesio, A., McMullan, S., Goridis, C., Fortin, G. and Brunet, J.F. ORCID: https://orcid.org/0000-0002-1985-6103
Nature Communications 12 : 6307. 2 November 2021

β-secretase BACE1 is required for normal cochlear function.
Dierich, M., Hartmann, S. ORCID: https://orcid.org/0000-0003-0981-5479, Dietrich, N., Moeser, P., Brede, F., Johnson Chacko, L., Tziridis, K., Schilling, A., Krauss, P., Hessler, S., Karch, S. ORCID: https://orcid.org/0000-0002-5101-3181, Schrott-Fischer, A., Blumer, M., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Oliver, D., Moser, T., Schulze, H., Alzheimer, C., Leitner, M.G. ORCID: https://orcid.org/0000-0002-3259-6481 and Huth, T. ORCID: https://orcid.org/0000-0002-6414-8923
Journal of Neuroscience 39 (45): 9013-9027. 6 November 2019

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S. ORCID: https://orcid.org/0000-0002-0753-9266, Company, C. ORCID: https://orcid.org/0000-0002-7975-0642, Song, K. ORCID: https://orcid.org/0000-0001-6216-8157, Lowenstein, E.D. ORCID: https://orcid.org/0000-0003-3755-0818, Riedel, L. ORCID: https://orcid.org/0000-0003-0389-8410, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Gargiulo, G. ORCID: https://orcid.org/0000-0001-5414-4251 and Zampieri, N. ORCID: https://orcid.org/0000-0002-2228-9453
Nature Communications 13 (1): 6867. 11 November 2022

Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons.
Dubreuil, V., Thoby-Brisson, M., Rallu, M., Persson, K., Pattyn, A., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Brunet, J.F., Fortin, G. and Goridis, C.
Journal of Neuroscience 29 (47): 14836-14846. 25 November 2009

Differential expression of neurotrophin receptors during renal development.
Durbeej, M., Soederstroem, S., Ebendal, T., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Ekblom, P.
Development 119 (4): 977-989. December 1993

Parasympathetic neurons originate from nerve-associated peripheral glial progenitors.
Dyachuk, V., Furlan, A., Shahidi, M.K., Giovenco, M., Kaukua, N., Konstantinidou, C., Pachnis, V., Memic, F., Marklund, U., Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Fried, K., Ernfors, P. and Adameyko, I.
Science 345 (6192): 82-87. 4 July 2014

Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities.
Ebel, P., Vom Dorp, K., Petrasch-Parwez, E., Zlomuzica, A., Kinugawa, K., Mariani, J., Minich, D., Ginkel, C., Welcker, J., Degen, J., Eckhardt, M., Dere, E., Doermann, P. and Willecke, K.
Journal of Biological Chemistry 288 (29): 21433-21447. 19 July 2013

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.
Espinosa-Medina, I., Jevans, B., Boismoreau, F., Chettouh, Z., Enomoto, H., Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Burns, Alan J and Brunet, J.F. ORCID: https://orcid.org/0000-0002-1985-6103
Proceedings of the National Academy of Sciences of the United States of America 114 (45): 11980-11985. 7 November 2017

Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis.
Esteves de Lima, J. ORCID: https://orcid.org/0000-0002-5497-5669, Bonnin, M.A., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Duprez, D. ORCID: https://orcid.org/0000-0003-0248-7417
eLife 5 : e15593. 24 August 2016

Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of Basal progenitors in the developing mouse neocortex.
Farkas, L.M., Haffner, C., Giger, T., Khaitovich, P., Nowick, K., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Paeaebo, S. and Huttner, W.B.
Neuron 60 (1): 40-55. 9 October 2008

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C. ORCID: https://orcid.org/0000-0003-0329-2435, Urzi, A., Vidal, R. ORCID: https://orcid.org/0000-0003-4217-2014, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Kabuss, L., Hube, I., Gazzerro, E. ORCID: https://orcid.org/0000-0003-2428-0302, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Sauer, S. ORCID: https://orcid.org/0000-0002-4794-3693 and Gouti, M. ORCID: https://orcid.org/0000-0001-7422-1605
Cell Stem Cell 26 (2): 172-186. 6 February 2020

BACE1 dependent neuregulin processing: review.
Fleck, D., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Haass, C. and Willem, M.
Current Alzheimer Research 9 (2): 178-183. February 2012

The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1.
Freese, C., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Fahrenholz, F. and Endres, K.
FEBS Journal 276 (6): 1568-1580. March 2009

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy.
Frezel, N., Ranucci, M., Foster, E., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Pelczar, P., Mendes, R., Ganley, R.P., Werynska, K., d'Aquin, S., Beccarini, C., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Zeilhofer, H.U. and Wildner, H. ORCID: https://orcid.org/0000-0001-5075-6269
Cell Reports 42 (4): 112295. 21 March 2023

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.
Fricker, F.R., Antunes-Martins, A., Galino, J., Paramsothy, R., La Russa, F., Perkins, J., Goldberg, R., Brelstaff, J., Zhu, N., McMahon, S.B., Orengo, C., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Bennett, D.L.
Brain 136 (Pt 7): 2279-2297. July 2013

Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood.
Fricker, F.R., Lago, N., Balarajah, S., Tsantoulas, C., Tanna, S., Zhu, N., Fageiry, S.K., Jenkins, M., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Bennett, D.L.
Journal of Neuroscience 31 (9): 3225-3233. 2 March 2011

Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.
Fricker, F.R., Zhu, N., Tsantoulas, C., Abrahamsen, B., Nassar, M.A., Thakur, M., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, McMahon, S.B., Wood, J.N. and Bennett, D.L.
Journal of Neuroscience 29 (24): 7667-7678. 17 June 2009

"To erb-B or not to erb-B..." Neuregulin-1/ErbB signaling in heart development and function.
Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041
Journal of Molecular and Cellular Cardiology 41 (2): 215-218. August 2006

A dual role of erbB2 in myelination and in expansion of the Schwann cell precursor pool.
Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Voiculescu, O., Topilko, P., Charnay, P. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Journal of Cell Biology 148 (5): 1035-1046. 6 March 2000

Targeting MET in cancer: rationale and progress.
Gherardi, E., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice.
Giebeler, A., Boekschoten, M.V., Klein, C., Borowiak, M. ORCID: https://orcid.org/0000-0002-5829-1213, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Gassler, N., Wasmuth, H.E., Mueller, M., Trautwein, C. and Streetz, K.L.
Gastroenterology 137 (1): 297-308. July 2009

The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
Gierl, M.S., Karoulias, N., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Strehle, M. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 20 (17): 2465-2478. 1 September 2006

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M. ORCID: https://orcid.org/0000-0001-7384-3429, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Liang, L., Vuralli, D., Froehler, S. ORCID: https://orcid.org/0000-0001-8000-2927, Kuehnen, P. ORCID: https://orcid.org/0000-0003-0211-176X, Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045, Jia, S. ORCID: https://orcid.org/0000-0001-8595-9314, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627 and Raile, K. ORCID: https://orcid.org/0000-0002-0842-1737
Molecular Genetics & Genomic Medicine 7 (5): e602. May 2019

Notch signaling is essential for ventricular chamber development.
Grego-Bessa, J., Luna-Zurita, L., del Monte, G., Bolos, V., Melgar, P., Arandilla, A., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Zang, H., Mukouyama, Y.S., Chen, H., Shou, W., Ballestar, E., Esteller, M., Rojas, A., Perez-Pomares, J.M. and de la Pompa, J.L.
Developmental Cell 12 (3): 415-429. March 2007

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence.
Griger, J. ORCID: https://orcid.org/0000-0001-8666-3371, Schneider, R., Lahmann, I. ORCID: https://orcid.org/0000-0003-0640-4519, Schöwel, V., Keller, C., Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Nazare, M. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
eLife 6 : e21552. 2 May 2017

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T., Stein, S., Qi, J., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Nave, K.A., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S., Rosario, M., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Advances in Cancer Research 106 : 53-89. 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Paul, F.E. ORCID: https://orcid.org/0000-0001-5181-3122, Cheret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Zurborg, S., Feinberg, K., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Schulz, H. ORCID: https://orcid.org/0000-0002-0226-964X, Peles, E., Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

CO(2) in the spotlight.
Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
eLife 4 : e08086. 13 May 2015

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice.
Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X, Ibrahim, D.M., Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Larrosa, M., Balueva, K., Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853, de Weerd, W., Stolte-Dijkstra, I., Hostra, R.M.W., Brunet, J.F. ORCID: https://orcid.org/0000-0002-1985-6103, Fortin, G., Mundlos, S. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 115 (51): 13021-13026. 18 December 2018

The dorsal spinal cord and hindbrain: from developmental mechanisms to functional circuits.
Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X, Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Developmental Biology 432 (1): 34-42. 1 December 2017

Genetic identification of a hindbrain nucleus essential for innate vocalization.
Hernandez-Miranda, L.R. ORCID: https://orcid.org/0000-0002-0498-708X, Ruffault, P.L. ORCID: https://orcid.org/0000-0002-3378-3828, Bouvier, J.C., Murray, A.J., Morin-Surun, M.P., Zampieri, N. ORCID: https://orcid.org/0000-0002-2228-9453, Cholewa-Waclaw, J.B. ORCID: https://orcid.org/0000-0001-8625-8528, Ey, E., Brunet, J.F., Champagnat, J., Fortin, G. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Proceedings of the National Academy of Sciences of the United States of America 114 (30): 8095-8100. 25 July 2017

A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice.
Hesse, M., Grund, C., Herrmann, H., Broehl, D., Franz, T., Omary, M.B. and Magin, T.M.
Experimental Cell Research 313 (14): 3127-3140. 15 August 2007

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling.
Hori, K., Cholewa-Waclaw, J. ORCID: https://orcid.org/0000-0001-8625-8528, Nakada, Y., Glasgow, S.M., Masui, T., Henke, R.M., Wildner, H., Martarelli, B., Beres, T.M., Epstein, J.A., Magnuson, M.A., Macdonald, R.J., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Johnson, J.E.
Genes & Development 22 (2): 166-178. 15 January 2008

Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J., Vogel, R., Brinkmann, V., Erdmann, B., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Journal of Cell Biology 148 (3): 567-578. 7 February 2000

Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors.
Humphries, J.D., Schofield, N.R., Mostafavi-Pour, Z., Green, L.J., Garratt, A.N. ORCID: https://orcid.org/0000-0001-9631-3041, Mould, A.P. and Humphries, M.J.
Journal of Biological Chemistry 280 (11): 10234-10243. 18 March 2005

Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.
Jacob, J., Storm, R., Castro, D.S., Milton, C., Pla, P., Guillemot, F., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Briscoe, J.
Development 136 (14): 2477-2485. July 2009

c-MAF transduces fast motor neuron firing to sustain fast-glycolytic myofibers and neuromuscular junctions.
Jauliac, Edgar ORCID: https://orcid.org/0009-0007-5049-6525, Backer, Stephanie, Sadaki, Shunya, Gondin, Julien, Fessard, Aurelie, Escoffier, Hugues, Roullat, Maeva, Di Gallo, Maxime, Levesque, Adrien, Pereira, Doriane, Dos Santos, Mattieu, Vuong, Vincent, Ham, Alexander S., Letourneur, Franck, Pierre, Rémi, Rüegg, Markus A. ORCID: https://orcid.org/0000-0002-4974-9384, Birchmeier, Carmen ORCID: https://orcid.org/0000-0002-2041-8872, Fujita, Ryo, Sotiropoulos, Athanassia and Maire, Pascal ORCID: https://orcid.org/0000-0001-7795-0029
bioRxiv : 2026.02.05.703983v2. 17 February 2026

Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1.
Jia, S. ORCID: https://orcid.org/0000-0001-8595-9314, Wildner, H. and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Developmental Biology 408 (1): 90-98. 1 December 2015

Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.
Jia, S. ORCID: https://orcid.org/0000-0001-8595-9314, Ivanov, A. ORCID: https://orcid.org/0000-0002-4824-1925, Blasevic, D., Müller, T. ORCID: https://orcid.org/0000-0001-8096-1853, Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Sun, W. ORCID: https://orcid.org/0000-0001-9607-1361, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
EMBO Journal 34 (10): 1417-1433. 12 May 2015

Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development.
John, A., Brylka, H., Wiegreffe, C., Simon, R., Liu, P., Juettner, R. ORCID: https://orcid.org/0000-0003-3565-0698, Crenshaw, E.B., Luyten, F.P., Jenkins, N.A., Copeland, N.G., Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872 and Britsch, S. ORCID: https://orcid.org/0000-0003-4379-3322
Development 139 (10): 1831-1841. 15 May 2012

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M. ORCID: https://orcid.org/0000-0002-6863-841X, Franke, V. ORCID: https://orcid.org/0000-0003-3606-6792, Brandt, B., Lowenstein, E.D. ORCID: https://orcid.org/0000-0003-3755-0818, Schöwel, V. ORCID: https://orcid.org/0000-0002-5924-3088, Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Nature Communications 11 : 6375. 11 December 2020

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M. ORCID: https://orcid.org/0000-0002-6863-841X, Wende, H. ORCID: https://orcid.org/0000-0002-9168-8095, Walcher, J., Kühnemund, J., Cheret, C. ORCID: https://orcid.org/0000-0001-7382-0403, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352 and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
Genes & Development 32 (9-10): 645-657. 10 May 2018

Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation.
Kim, M. ORCID: https://orcid.org/0000-0002-6863-841X, Zhang, Y. ORCID: https://orcid.org/0000-0001-5841-225X and Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872
bioRxiv : 2020.12.22.424062. 22 December 2020

SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta.
Kirchenwitz, M. ORCID: https://orcid.org/0000-0002-9170-936X, Stahnke, S., Prettin, S., Borowiak, M. ORCID: https://orcid.org/0000-0002-5829-1213, Menke, L., Sieben, C. ORCID: https://orcid.org/0000-0002-2836-2623, Birchmeier, C. ORCID: https://orcid.org/0000-0002-2041-8872, Rottner, K. ORCID: https://orcid.org/0000-0003-4244-4198, Stradal, T.E.B. and Steffen, A. ORCID: https://orcid.org/0000-0002-2933-0543
Cells 11 (10): 1648. 16 May 2022