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Akalin, Altuna (BIMSB)

Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A., Gündüz, I.B., Franke, V., Uyar, B. and Akalin, A.
Cancers 14 (22): 5604. 15 November 2022

The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L., Morao, A.K., Kim, J., Jimenez, D.S., Maryn, N., Bikkasani, K., Carrozza, M.J., Albritton, S.E., Kramer, M., Street, L.A., Cerimi, K., Schumann, V.F., Bahry, E., Preibisch, S., Woehler, A. and Ercan, S.
Journal of Cell Science 135 (2): jcs258818. January 2022

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C., Rom, A., Franke, V., Imami, K., Arrey, G., Terne, M., Woehler, A., Akalin, A., Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V., Berruezo-Llacuna, M., Altwasser, R., Winkler, W., Sundaravinayagam, D., Balasubramanian, S., Caganova, M., Graf, R., Rahjouei, A., Henke, M.T., Driesner, M., Keller, L., Prigione, A., Janz, M., Akalin, A. and Di Virgilio, M.
Journal of Experimental Medicine 217 (10): e20200137. 5 October 2020

Nuclear organization in the spinal cord depends on motor neuron lamination orchestrated by catenin and afadin function.
Dewitz, C., Pimpinella, S., Hackel, P., Akalin, A., Jessell, T.M. and Zampieri, N.
Cell Reports 22 (7): 1681-1694. 13 February 2018

Identifying tumor cells at the single-cell level using machine learning.
Dohmen, J., Baranovskii, A., Ronen, J., Uyar, B., Franke, V. and Akalin, A.
Genome Biology 23 (1): 123. 30 May 2022

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M., Franke, V., Brandt, B., Lowenstein, E.D., Schöwel, V., Spuler, S., Akalin, A. and Birchmeier, C.
Nature Communications 11 : 6375. 11 December 2020

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E., Ofenbauer, A., Bulut, S.I., Uyar, B., Baytek, G., Sommermeier, A., Seelk, S., He, M., Hirsekorn, A., Vucicevic, D., Akalin, A., Diecke, S., Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

Lymphocyte access to lymphoma is impaired by high endothelial venule regression.
Menzel, L., Zschummel, M., Crowley, T., Franke, V., Grau, M., Ulbricht, C., Hauser, A., Siffrin, V., Bajénoff, M., Acton, S.E., Akalin, A., Lenz, G., Willimsky, G., Höpken, U.E. and Rehm, A.
Cell Reports 37 (4): 109878. 26 October 2021

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K., Kirchner, M., Uyar, B., Cheng, J.Y., Russo, G., Hernandez-Miranda, L.R., Szymborska, A., Zauber, H., Rudolph, I.M., Willnow, T.E., Akalin, A., Haucke, V., Gerhardt, H., Birchmeier, C., Kühn, R., Krauss, M., Diecke, S., Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S., Uyar, B., He, M., Krause, A., Vitrinel, B., Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S., Akalin, A. and Tursun, B.
Aging Cell 18 (6): e13012. December 2019

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T., Meyer, K., Roske, Y., Uyar, B., Akalin, A., Imami, K., Ishihama, Y., Daumke, O. and Selbach, M.
Nature Communications 15 (1): 3146. 11 April 2024

Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J., Sundaravinayagam, D., Blume, A., Marg, A., Grunwald, S., Metzler, E., Escobar, H., Müthel, S., Wang, H., Wollersheim, T., Weber-Carstens, S., Akalin, A., Di Virgilio, M., Tursun, B. and Spuler, S.
International Journal of Molecular Sciences 24 (3): 2772. 1 February 2023

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F., de Castro Cuadrat, R.R., Wyler, E., Wurmus, R., Deter, A., Quedenau, C., Dohmen, J., Faxel, M., Borodina, T., Blume, A., Freimuth, J., Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B., Franke, V., Barke, N., Altmüller, J., Rajewsky, N., Landthaler, M. and Akalin, A.
Science of the Total Environment 853 : 158931. 20 December 2022

HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K., Franke, V., Uyar, B., Wurmus, R., Bulut, S., Tursun, B. and Akalin, A.
Nucleic Acids Research : gkz460. 20 June 2019

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E., Mösbauer, K., Franke, V., Diag, A., Gottula, L.T., Arsiè, R., Klironomos, F., Koppstein, D., Hönzke, K., Ayoub, S., Buccitelli, C., Hoffmann, K., Richter, A., Legnini, I., Ivanov, A., Mari, T., Del Giudice, S., Papies, J., Praktiknjo, S., Meyer, T.F., Müller, M.A., Niemeyer, D., Hocke, A., Selbach, M., Akalin, A., Rajewsky, N., Drosten, C. and Landthaler, M.
iScience 24 (3): 102151. 19 March 2021

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A., van den Bruck, D., Ciolli Mattioli, C., Franke, V., Imami, K., McShane, E., Moreno-Estelles, M., Calviello, L., Filipchyk, A., Peguero-Sanchez, E., Müller, T., Woehler, A., Birchmeier, C., Merino, E., Rajewsky, N., Ohler, U., Mazzoni, E.O., Selbach, M., Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V., McShane, E., Schulz-Beiss, K.W., Patone, G., Schleussner, N., Kolesnichenko, M., Hübner, N., Daumke, O., Selbach, M., Akalin, A., Mathas, S. and Scheidereit, C.
Blood 133 (13): 1489-1494. 28 March 2019

Alexander, Christiane

Characterization of OPA1 isoforms isolated from mouse tissues.
Akepati, V.R., Mueller, E.C., Otto, A., Strauss, H., Portwich, M. and Alexander, C.
Journal of Neurochemistry 106 (1): 372-383. July 2008

Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy.
Fuhrmann, N., Schimpf, S., Kamenisch, Y., Leo-Kottler, B., Alexander, C., Auburger, G., Zrenner, E., Wissinger, B. and Alavi, M.V.
Molecular Neurodegeneration 5 (1): 25. 14 June 2010

Molekulargenetische Identifizierung von Determinanten der photoparoxysmalen Reaktion.
Lorenz, S.
UNSPECIFIED thesis, UNSPECIFIED. 25 July 2006

Candidate gene analysis of the succinic semialdehyde dehydrogenase gene (ALDH5A1) in patients with idiopathic generalized epilepsy and photosensitivity.
Lorenz, S., Heils, A., Taylor, K.P., Gehrmann, A., Muhle, H., Gresch, M., Becker, T., Tauer, U., Stephani, U. and Sander, T.
Neuroscience Letters 397 (3): 234-239. 24 April 2006

OPA1, the disease gene for autosomal dominant optic atrophy, is specifically expressed in ganglion cells and intrinsic neurons of the retina.
Pesch, U.E.A., Fries, J.E., Bette, S., Kalbacher, H., Wissinger, B., Alexander, C. and Kohler, K.
Investigative Ophthalmology & Visual Science 45 (11): 4217-4225. 1 January 2004

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.
Song, Z., Chen, H., Fiket, M., Alexander, C. and Chan, D.C.
Journal of Cell Biology 178 (5): 749-755. 27 August 2007

Altmüller, Janine (BIMSB/BIH)

In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia.
Bakina, O., Conrad, T., Mitic, N., Vidal, R.O., Obrusnik, T., Sai, S., Nolte, C., Semtner, M. and Kettenmann, H.
PLoS ONE 19 (7): e0302376. 11 July 2024

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C., Urzi, A., Vidal, R., Kunz, S., Ruffault, P.L., Kabuss, L., Hube, I., Gazzerro, E., Birchmeier, C., Spuler, S., Sauer, S. and Gouti, M.
Cell Stem Cell 26 (2): 172-186. 6 February 2020

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J., Muinjonov, B., Rosiewicz, K.S., Diecke, S., Biese, C., Schiweck, J., Chien, C., Zocholl, D., Conrad, T., Paul, F., Alisch, M. and Siffrin, V.
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E., Escobar, H., Sunaga-Franze, D.Y., Sauer, S., Diecke, S. and Spuler, S.
Biomedicines 10 (5): 1204. 23 May 2022

A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A., Bakina, O., Badillo Lisakowski, V., Olivares-Chauvet, P., Conrad, T., Gotthardt, M., Kettenmann, H. and Junker, J.P.
Molecular Systems Biology 19 (2): e11147. 10 February 2023

Rare variants in GABA(A) receptor genes in Rolandic epilepsy and related syndromes.
Reinthaler, E.M., Dejanovic, B., Lal, D., Semtner, M., Merkler, Y., Reinhold, A., Pittrich, D.A., Hotzy, C., Feucht, M., Steinboeck, H., Gruber-Sedlmayr, U., Ronen, G., Neophytou, B., Geldner, J., Haberlandt, E., Muhle, H., Ikram, M.A., van Duijn, CM., Uitterlinden, A.G., Hofman, A., Altmüller, J., Kawalia, A., Toliat, M.R., Nuernberg, P., Lerche, H., Nothnagel, M., Thiele, H., Sander, T., Meier, J.C., Schwarz, G., Neubauer, B.A. and Zimprich, F.
Annals of Neurology 77 (6): 972-986. June 2015

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F., de Castro Cuadrat, R.R., Wyler, E., Wurmus, R., Deter, A., Quedenau, C., Dohmen, J., Faxel, M., Borodina, T., Blume, A., Freimuth, J., Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B., Franke, V., Barke, N., Altmüller, J., Rajewsky, N., Landthaler, M. and Akalin, A.
Science of the Total Environment 853 : 158931. 20 December 2022

Andrade Navarro, Miguel

Aversion to nicotine is regulated by the balanced activity of beta4 and alpha5 nicotinic receptor subunits in the medial habenula.
Frahm, S., Slimak, M.A., Ferrarese, L., Santos-Torres, J., Antolin-Fontes, B., Auer, S., Filkin, S., Pons, S., Fontaine, J.F., Tsetlin, V., Maskos, U. and Ibanez-Tallon, I.
Neuron 70 (3): 522-535. 12 May 2011

Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains.
Haenig, C., Atias, N., Taylor, A.K., Mazza, A., Schaefer, M.H., Russ, J., Riechers, S.P., Jain, S., Coughlin, M., Fontaine, J.F., Freibaum, B.D., Brusendorf, L., Zenkner, M., Porras, P., Stroedicke, M., Schnoegl, S., Arnsburg, K., Boeddrich, A., Pigazzini, L., Heutink, P., Taylor, J.P., Kirstein, J., Andrade-Navarro, M.A., Sharan, R. and Wanker, E.E.
Cell Reports 32 (7): 108050. 18 August 2020

Detection of alpha-rod protein repeats using a neural network and application to huntingtin.
Palidwor, G.A., Shcherbinin, S., Huska, M.R., Rasko, T., Stelzl, U., Arumughan, A., Foulle, R., Porras, P., Sanchez-Pulido, L., Wanker, E.E. and Andrade-Navarro, M.A.
PLoS Computational Biology 5 (3): e1000304. 13 March 2009

Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
Petrakis, S., Rasko, T., Russ, J., Friedrich, R.P., Stroedicke, M., Riechers, S.P., Muehlenberg, K., Moeller, A., Reinhardt, A., Vinayagam, A., Schaefer, M.H., Boutros, M., Tricoire, H., Andrade-Navarro, M.A. and Wanker, E.E.
PLoS Genetics 8 (8): e1002897. 16 August 2012

Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
Petrakis, S., Schaefer, M.H., Wanker, E.E. and Andrade-Navarro, M.A.
BioEssays 35 (6): 503-507. June 2013

HIPPIE: integrating protein interaction networks with experiment based quality scores.
Schaefer, M.H., Fontaine, J.F., Vinayagam, A., Porras, P., Wanker, E.E. and Andrade-Navarro, M.A.
PLoS ONE 7 (2): e31826. 14 February 2012

Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Schaefer, M.H., Wanker, E.E. and Andrade-Navarro, M.A.
Nucleic Acids Research 40 (10): 4273-4287. 1 May 2012

Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke, M., Bounab, Y., Strempel, N., Klockmeier, K., Yigit, S., Friedrich, R.P., Chaurasia, G., Li, S., Hesse, F., Riechers, S.P., Russ, J., Nicoletti, C., Boeddrich, A., Wiglenda, T., Haenig, C., Schnoegl, S., Fournier, D., Graham, R.K., Hayden, M.R., Sigrist, S., Bates, G.P., Priller, J., Andrade-Navarro, M.A., Futschik, M.E. and Wanker, E.E.
Genome Research 25 (5): 701-713. May 2015

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
Suratanee, A., Schaefer, M.H., Betts, M.J., Soons, Z., Mannsperger, H., Harder, N., Oswald, M., Gipp, M., Ramminger, E., Marcus, G., Männer, R., Rohr, K., Wanker, E., Russell, R.B., Andrade-Navarro, M.A., Eils, R. and König, R.
PLoS Computational Biology 10 (9): e1003814. 25 September 2014

Development and application of a DNA microarray-based yeast two-hybrid system.
Suter, B., Fontaine, J.F., Yildirimman, R., Raskó, T., Schaefer, M.H., Rasche, A., Porras, P., Vázquez-Álvarez, B.M., Russ, J., Rau, K., Foulle, R., Zenkner, M., Saar, K., Herwig, R., Andrade-Navarro, M.A. and Wanker, E.E.
Nucleic Acids Research 41 (3): 1496-507. 1 February 2013

A directed protein interaction network for investigating intracellular signal transduction.
Vinayagam, A., Stelzl, U., Foulle, R., Plassmann, S., Zenkner, M., Timm, J., Assmus, H.E., Andrade-Navarro, M.A. and Wanker, E.E.
Science Signaling 4 (189): rs8. 6 September 2011

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K., Ullrich, F., Muench, J., Lazarow, K., Lutter, D., Mah, N., Andrade-Navarro, M.A., von Kries, J.P., Stauber, T. and Jentsch, T.J.
Science 344 (6184): 634-638. 9 May 2014

Arnold, Susanne

Estrogen suppresses the impact of glucose deprivation on astrocytic calcium levels and signaling independently of the nuclear estrogen receptor.
Arnold, S.
Neurobiology of Disease 20 (1): 82-92. October 2005

The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases.
Kadenbach, B., Arnold, S., Lee, I. and Huettemann, M.
Biochimica et Biophysica Acta - Bioenergetics 1655 : 400-408. 1 January 2004

BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum.
Westphalen, B.C., Wessig, J., Leypoldt, F., Arnold, S. and Methner, A.
Cell Death and Differentiation 12 (3): 304-306. 1 March 2005

Bader, Michael

Reduced nerve injury-induced neuropathic pain in kinin B1 receptor knock-out mice.
Ferreira, J., Beirith, A., Mori, M.A., Araújo, R.C., Bader, M., Pesquero, J.B. and Calixto, J.B.
Journal of Neuroscience 25 (9): 2405-2412. 2 March 2005

Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders.
Hadar, R., Edemann-Callesen, H., Reinel, C., Wieske, F., Voget, M., Popova, E., Sohr, R., Avchalumov, Y., Priller, J., van Riesen, C., Puls, I., Bader, M. and Winter, C.
Scientific Reports 6 : 39145. 15 December 2016

Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger.
Ifuku, M., Faerber, K., Okuno, Y., Yamakawa, Y., Miyamoto, T., Nolte, C., Merrino, V.F., Kitada, S., Iwamoto, T., Komuro, I., Wang, B., Cheung, G., Ishikawa, E., Ooboshi, H., Bader, M., Wada, K., Kettenmann, H. and Noda, M.
Journal of Neuroscience 27 (48): 13065-13073. 28 November 2007

Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G., Uhlemann, R., Richter, N., Klempin, F., Wegner, S., Staerck, L., Wolf, S., Uckert, W., Kettenmann, H., Endres, M. and Gertz, K.
Acta Neuropathologica 135 (4): 551. April 2018

Exon skipping in a Dysf-missense mutant mouse model.
Malcher, J., Heidt, L., Goyenvalle, A., Escobar, H., Marg, A., Beley, C., Benchaouir, R., Bader, M., Spuler, S., García, L. and Schöwel, V.
Molecular Therapy - Nucleic Acids 13 : 198-207. 7 December 2018

Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.
Schleifenbaum, J., Kassmann, M., Szijártó, I.A., Hercule, H.C., Tano, J.Y., Weinert, S., Heidenreich, M., Pathan, A.R., Anistan, Y.M., Alenina, N., Rusch, N.J., Bader, M., Jentsch, T.J. and Gollasch, M.
Circulation Research 115 (2): 263-272. 7 July 2014

Roles of the kallikrein/kinin system in the adaptive immune system.
Schulze-Topphoff, U., Prat, A., Bader, M., Zipp, F. and Aktas, O.
International Immunopharmacology 8 (2): 155-160. February 2008

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system.
Schulze-Topphoff, U., Prat, A., Prozorovski, T., Siffrin, V., Paterka, M., Herz, J., Bendix, I., Ifergan, I., Schadock, I., Mori, M.A., Van Horssen, J., Schroeter, F., Smorodchenko, A., Han, M.H., Bader, M., Steinman, L., Aktas, O. and Zipp, F.
Nature Medicine 15 (7): 788-793. July 2009

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Yalcin, F., Haneke, H., Efe, I.E., Kuhrt, L.D., Motta, E., Nickl, B., Flüh, C., Synowitz, M., Dzaye, O., Bader, M. and Kettenmann, H.
Acta Neuropathologica Communications 12 (1): 50. 2 April 2024

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting.
Zanders, L., Kny, M., Hahn, A., Schmidt, S., Wundersitz, S., Todiras, M., Lahmann, I., Bandyopadhyay, A., Wollersheim, T., Kaderali, L., Luft, F.C., Birchmeier, C., Weber-Carstens, S. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 13 (1): 713-727. February 2021

Discovering the mechanisms underlying serotonin (5-HT)2A and 5-HT2C receptor regulation following nicotine withdrawal in rats.
Zaniewska, M., Alenina, N., Wydra, K., Fröhler, S., Kuśmider, M., McCreary, A.C., Chen, W., Bader, M. and Filip, M.
Journal of Neurochemistry 134 (4): 704-716. August 2015

Behlke, Joachim

Self-association of adrenodoxin studied by using analytical ultracentrifugation.
Behlke, J., Ristau, O., Mueller, E.C., Hannemann, F. and Bernhardt, R.
Biophysical Chemistry 125 (1): 159-165. January 2007

Besser, Daniel

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R., Sternjak, A., Wend, P., Momma, S., Campos, B., Herrmann, I.M., Graf, D., Mitsiadis, T., Herold-Mende, C., Besser, D., Synowitz, M., Kettenmann, H. and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H., Paul, F.E., Cheret, C., Garratt, A.N., Zurborg, S., Feinberg, K., Besser, D., Schulz, H., Peles, E., Selbach, M., Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J., Xie, G., Singh, M., Ghanbarian, A.T., Raskó, T., Szvetnik, A., Cai, H., Besser, D., Prigione, A., Fuchs, N.V., Schumann, G.G., Chen, W., Lorincz, M.C., Ivics, Z., Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Beule, Dieter (MDC/BIH)

Disrupting TSLP-TSLP receptor interactions via putative small molecule inhibitors yields a novel and efficient treatment option for atopic diseases.
Adhikary, P.P., Idowu, T., Tan, Z., Hoang, C., Shanta, S., Dumbani, M., Mappalakayil, L., Awasthi, B., Bermudez, M., Weiner, J., Beule, D., Wolber, G., Page, B.D. and Hedtrich, S.
EMBO Molecular Medicine 16 (7): 1630-1656. 15 July 2024

The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A., Babila, J.T., Wiglenda, T., Diez, L., Jacob, M., Nietfeld, W., Huska, M.R., Haenig, C., Groenke, N., Buntru, A., Blanc, E., Meier, J.C., Vannoni, E., Erck, C., Friedrich, B., Martens, H., Neuendorf, N., Schnoegl, S., Wolfer, D.P., Loos, M., Beule, D., Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26 (1): 109-120. 17 January 2019

A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A., Haenig, C., Neuendorf, N., Blanc, E., Ivanov, A., Kirchner, M., Schleumann, P., Bayraktaroğlu, I., Richter, M., Molenda, C.M., Sporbert, A., Zenkner, M., Schnoegl, S., Suenkel, C., Schneider, L.S., Rybak-Wolf, A., Kochnowsky, B., Byrne, L.M., Wild, E.J., Nielsen, J.E., Dittmar, G., Peters, O., Beule, D. and Wanker, E.E.
Genome Medicine 15 (1): 50. 20 July 2023

let-7 microRNAs regulate microglial function and suppress glioma growth through Toll-like receptor 7.
Buonfiglioli, A., Efe, I.E., Guneykaya, D., Ivanov, A., Huang, Y., Orlowski, E., Krüger, C., Deisz, R.A., Markovic, D., Flüh, C., Newman, A.G., Schneider, U.C., Beule, D., Wolf, S.A., Dzaye, O., Gutmann, D.H., Semtner, M., Kettenmann, H. and Lehnardt, S.
Cell Reports 29 (11): 3460-3471. 10 December 2019

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M., Klinger, B., Mari, T., Toedling, J., Blanc, E., Messerschmidt, C., Nadler-Holly, M., Ziehm, M., Sieber, A., Hertwig, F., Beule, D., Eggert, A., Schulte, J.H., Selbach, M. and Blüthgen, N.
PLoS Computational Biology 17 (11): e1009515. 4 November 2021

Extracellular matrix remodeling in atopic dermatitis harnesses the onset of an asthmatic phenotype and is a potential contributor to the atopic march.
Graff, P., Woerz, D., Wilzopolski, J., Voss, A., Sarrazin, J., Blimkie, T.M., Weiner, J., Kershaw, O., Panwar, P., Hackett, T., Lau, S., Brömme, D., Beule, D., Lee, Y.A., Hancock, R.E.W., Gruber, A.D., Bäumer, W. and Hedtrich, S.
Journal of Investigative Dermatology 144 (5): 1010-1021. May 2024

Transcriptional and translational differences of microglia from male and female brains.
Guneykaya, D., Ivanov, A., Perez Hernandez, D., Haage, V., Wojtas, B., Meyer, N., Maricos, M., Jordan, P., Buonfiglioli, A., Gielniewski, B., Ochocka, N., Cömert, C., Friedrich, C., Suarez Artiles, L., Kaminska, B., Mertins, P., Beule, D., Kettenmann, H. and Wolf, S.A.
Cell Reports 24 (10): 2773-2783. 4 September 2018

Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
Hönzke, K., Obermayer, B., Mache, C., Fathykova, D., Kessler, M., Dökel, S., Wyler, E., Baumgardt, M., Löwa, A., Hoffmann, K., Graff, P., Schulze, J., Mieth, M., Hellwig, K., Demir, Z., Biere, B., Brunotte, L., Mecate-Zambrano, A., Bushe, J., Dohmen, M., Hinze, C., Elezkurtaj, S., Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Schmidt-Ott, K.M., Busch, J., Klauschen, F., Horst, D., Radbruch, H., Radke, J., Heppner, F., Corman, V.M., Niemeyer, D., Müller, M.A., Goffinet, C., Mothes, R., Pascual-Reguant, A., Hauser, A.E., Beule, D., Landthaler, M., Ludwig, S., Suttorp, N., Witzenrath, M., Gruber, A.D., Drosten, C., Sander, L.E., Wolff, T., Hippenstiel, S. and Hocke, A.C.
European Respiratory Journal 60 (6): 2102725. 1 December 2022

Protein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit.
Kraushar, M.L., Krupp, F., Harnett, D., Turko, P., Ambrozkiewicz, M.C., Sprink, T., Imami, K., Günnigmann, M., Zinnall, U., Vieira-Vieira, C.H., Schaub, T., Münster-Wandowski, A., Bürger, J., Borisova, E., Yamamoto, H., Rasin, M.R., Ohler, U., Beule, D., Mielke, T., Tarabykin, V., Landthaler, M., Kramer, G., Vida, I., Selbach, M. and Spahn, C.M.T.
Molecular Cell 81 (2): 304-322. 21 January 2021

Microglia undergo molecular and functional adaptations to dark and light phases in male laboratory mice.
Mattei, D., Ivanov, A., Hammer, J., Ugursu, B., Schalbetter, S., Richetto, J., Weber-Stadlbauer, U., Mueller, F., Scarborough, J., Wolf, S.A., Kettenmann, H., Wollscheid, B., Beule, D. and Meyer, U.
Brain Behavior and Immunity 210 : 571-583. August 2024

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Mattei, D., Ivanov, A., Ferrai, C., Jordan, P., Guneykaya, D., Buonfiglioli, A., Schaafsma, W., Przanowski, P., Deuther-Conrad, W., Brust, P., Hesse, S., Patt, M., Sabri, O., Ross, T.L., Eggen, B.J.L., Boddeke, E.W.G.M., Kaminska, B., Beule, D., Pombo, A., Kettenmann, H. and Wolf, S.A.
Translational Psychiatry 7 (5): e1120. 9 May 2017

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E., Mösbauer, K., Franke, V., Diag, A., Gottula, L.T., Arsiè, R., Klironomos, F., Koppstein, D., Hönzke, K., Ayoub, S., Buccitelli, C., Hoffmann, K., Richter, A., Legnini, I., Ivanov, A., Mari, T., Del Giudice, S., Papies, J., Praktiknjo, S., Meyer, T.F., Müller, M.A., Niemeyer, D., Hocke, A., Selbach, M., Akalin, A., Rajewsky, N., Drosten, C. and Landthaler, M.
iScience 24 (3): 102151. 19 March 2021

Bimmler, Marion

Agonistic autoantibodies to the alpha(1)-adrenergic receptor and the beta(2)-adrenergic receptor in Alzheimer's and vascular dementia.
Karczewski, P., Hempel, P., Kunze, R. and Bimmler, M.
Scandinavian Journal of Immunology 75 (5): 524-530. May 2012

Cerebral blood volume estimation by ferumoxytol-enhanced steady-state MRI at 9.4 T reveals microvascular impact of α(1)-adrenergic receptor antibodies.
Pohlmann, A., Karczewski, P., Ku, M.C., Dieringer, B., Waiczies, H., Wisbrun, N., Kox, S., Palatnik, I., Reimann, H.M., Eichhorn, C., Waiczies, S., Hempel, P., Lemke, B., Niendorf, T. and Bimmler, M.
NMR in Biomedicine 27 (9): 1085-1093. September 2014

Birchmeier, Walter

Met, metastasis, motility and more.
Birchmeier, C., Birchmeier, W., Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.
Chirasani, S.R., Sternjak, A., Wend, P., Momma, S., Campos, B., Herrmann, I.M., Graf, D., Mitsiadis, T., Herold-Mende, C., Besser, D., Synowitz, M., Kettenmann, H. and Glass, R.
Brain 133 (Pt 7): 1961-1972. July 2010

c-Met is essential for wound healing in the skin.
Chmielowiec, J., Borowiak, M., Morkel, M., Stradal, T., Munz, B., Werner, S., Wehland, J., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

Targeting MET in cancer: rationale and progress.
Gherardi, E., Birchmeier, W., Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T., Stein, S., Qi, J., Wende, H., Garratt, A.N., Nave, K.A., Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S., Rosario, M., Birchmeier, C. and Birchmeier, W.
Advances in Cancer Research 106 : 53-89. 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H., Paul, F.E., Cheret, C., Garratt, A.N., Zurborg, S., Feinberg, K., Besser, D., Schulz, H., Peles, E., Selbach, M., Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J., Vogel, R., Brinkmann, V., Erdmann, B., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 148 (3): 567-578. 7 February 2000

Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.
Rosario, M., Schuster, S., Juettner, R., Parthasarathy, S., Tarabykin, V. and Birchmeier, W.
Genes & Development 26 (15): 1743-1757. 1 August 2012

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E., McShane, E., Cheret, C., Walcher, J., Müller, T., Wulf-Goldenberg, A., Hoelper, S., Garratt, A.N., Krüger, M., Rajewsky, K., Meijer, D., Birchmeier, W., Lewin, G.R., Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: comparative analysis using six species of bathyergidae.
Smith, E.S.J., Purfürst, B., Grigoryan, T., Park, T.J., Bennett, N.C. and Lewin, G.R.
Journal of Comparative Neurology 520 (12): 2785-2803. 15 August 2012

A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl, U., Worm, U., Lalowski, M., Haenig, C., Brembeck, F.H., Goehler, H., Stroedicke, M., Zenkner, M., Schoenherr, A., Koeppen, S., Timm, J., Mintzlaff, S., Abraham, C., Bock, N., Kietzmann, S., Goedde, A., Toksoez, E., Droege, A., Krobitsch, S., Korn, B., Birchmeier, W., Lehrach, H. and Wanker, E.E.
Cell 122 (6): 957-968. 23 September 2005

Birchmeier-Kohler, Carmen

Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin.
Adameyko, I., Lallemend, F., Aquino, J.B., Pereira, J.A., Topilko, P., Mueller, T., Fritz, N., Beljajeva, A., Mochii, M., Liste, I., Usoskin, D., Suter, U., Birchmeier, C. and Ernfors, P.
Cell 139 (2): 366-379. 16 October 2009

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest.
Adameyko, I., Lallemend, F., Furlan, A., Zinin, N., Aranda, S., Kitambi, S.S., Blanchart, A., Favaro, R., Nicolis, S., Luebke, M., Mueller, T., Birchmeier, C., Suter, U., Zaitoun, I., Takahashi, Y. and Ernfors, P.
Development 139 (2): 397-410. 15 January 2012

Cell fixation and preservation for droplet-based single-cell transcriptomics.
Alles, J., Karaiskos, N., Praktiknjo, S.D., Grosswendt, S., Wahle, P., Ruffault, P.L., Ayoub, S., Schreyer, L., Boltengagen, A., Birchmeier, C., Zinzen, R., Kocks, C. and Rajewsky, N.
BMC Biology 15 (1): 44. 19 May 2017

Touch receptor-derived sensory information alleviates acute pain signaling and fine-tunes nociceptive reflex coordination.
Arcourt, A., Gorham, L., Dhandapani, R., Prato, V., Taberner, F.J., Wende, H., Gangadharan, V., Birchmeier, C., Heppenstall, P.A. and Lechner, S.G.
Neuron 93 (1): 179-193. 4 January 2017

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.
Atanasoski, S., Scherer, S.S., Sirkowski, E., Leone, D., Garratt, A.N., Birchmeier, C. and Suter, U.
Journal of Neuroscience 26 (7): 2124-2131. 15 February 2006

The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity.
Baek, J.H., Birchmeier, C., Zenke, M. and Hieronymus, T.
Journal of Immunology 189 (4): 1699-1707. 15 August 2012

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.
Bartus, K., Galino, J., James, N.D., Hernandez-Miranda, L.R., Dawes, J.M., Fricker, F.R., Garratt, A.N., McMahon, S.B., Ramer, M.S., Birchmeier, C., Bennett, D.L.H. and Bradbury, E.J.
Brain 139 (Pt 5): 1394-1416. May 2016

Development and more.
Birchmeier, C.
Seminars in Cell & Developmental Biology 21 (8): 812-813. October 2010

A fresh breeze from the ivory tower.
Birchmeier, C.
Current Opinion in Cell Biology 21 (6): 725-726. December 2009

ErbB receptors and the development of the nervous system.
Birchmeier, C.
Experimental Cell Research 315 (4): 611-618. 15 February 2009

Met, metastasis, motility and more.
Birchmeier, C., Birchmeier, W., Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003

Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation.
Birchmeier, C. and Nave, K.A.
Glia 56 (14): 1491-1497. 1 November 2008

Regulation of developmental tempo in different vertebrate species.
Birchmeier, C.
Cell Stem Cell 30 (7): 907-908. 6 July 2023

Preface.
Birchmeier, C.
Current Topics in Developmental Biology 97 : xi-xii. 2011

Neuregulin/ErbB signaling in developmental myelin formation and nerve repair.
Birchmeier, C. and Bennett, D.L.H.
Current Topics in Developmental Biology 116 : 45-64. 2016

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud.
Bladt, F., Riethmacher, D., Isenmann, S., Aguzzi, A. and Birchmeier, C.
Nature 376 (6543): 768-771. 31 August 1995

Molecular characterization of the intact mouse muscle spindle using a multi-omics approach.
Bornstein, B., Heinemann-Yerushalmi, L., Krief, S., Adler, R., Dassa, B., Leshkowitz, D., Kim, M.C., Bewick, G., Banks, R.W. and Zelzer, E.
eLife 12 : e81843. 6 February 2023

Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Brinkmann, B.G., Agarwal, A., Sereda, M.W., Garratt, A.N., Mueller, T., Wende, H., Stassart, R.M., Nawaz, S., Humml, C., Velanac, V., Radyushkin, K., Goebbels, S., Fischer, T.M., Franklin, R.J., Lai, C., Ehrenreich, H., Birchmeier, C., Schwab, M.H. and Nave, K.A.
Neuron 59 (4): 581-595. 28 August 2008

Transgenic and knock-out animals.
Britsch, S.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1900-1903. ISBN 3-540-44244-8 2006

Tiermodelle in der biomedizinischen Forschung.
Britsch, S., Strehle, M. and Birchmeier, C.
In: Grundlagen der Molekularen Medizin. Molekulare Medizin . Springer, Berlin [u.a.], 299-339. ISBN 3-540-43207-8 1 January 2003

A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord.
Broehl, D., Strehle, M., Wende, H., Hori, K., Bormuth, I., Nave, K.A., Mueller, T. and Birchmeier, C.
Developmental Biology 322 (2): 381-393. 15 October 2008

Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on notch signals.
Broehl, D., Vasyutina, E., Czajkowski, M.T., Griger, J., Rassek, C., Rahn, H.P., Purfürst, B., Wende, H. and Birchmeier, C.
Developmental Cell 23 (3): 469-481. 11 September 2012

Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3.
Cadot, B., Gache, V., Vasyutina, E., Falcone, S., Birchmeier, C. and Gomes, E.R.
EMBO Reports 13 (8): 741-749. 1 August 2012

Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4.
Caubit, X., Lye, C.M., Martin, E., Core, N., Long, D.A., Vola, C., Jenkins, D., Garratt, A.N., Skaer, H., Woolf, A.S. and Fasano, L.
Development 135 (19): 3301-3310. October 2008

Sustained MAPK/ERK activation in adult Schwann cells impairs nerve repair.
Cervellini, I., Galino, J., Zhu, N., Allen, S., Birchmeier, C. and Bennett, D.L.
Journal of Neuroscience 38 (3): 679-690. 17 January 2018

Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.
Chaimowicz, C., Ruffault, P.L., Chéret, C., Woehler, A., Zampieri, N., Fortin, G., Garratt, A.N. and Birchmeier, C.
Development 146 (17): dev174045. 6 September 2019

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.
Cheret, C., Willem, M., Fricker, F.R., Wende, H., Wulf-Goldenberg, A., Tahirovic, S., Nave, K.A., Saftig, P., Haass, C., Garratt, A.N., Bennett, D.L. and Birchmeier, C.
EMBO Journal 32 (14): 2015-2028. 17 July 2013

c-Met is essential for wound healing in the skin.
Chmielowiec, J., Borowiak, M., Morkel, M., Stradal, T., Munz, B., Werner, S., Wehland, J., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 177 (1): 151-162. 9 April 2007

A validated regulatory network for Th17 cell specification.
Ciofani, M., Madar, A., Galan, C., Sellars, M., Mace, K., Pauli, F., Agarwal, A., Huang, W., Parkurst, C.N., Muratet, M., Newberry, K.M., Meadows, S., Greenfield, A., Yang, Y., Jain, P., Kirigin, F.K., Birchmeier, C., Wagner, E.F., Murphy, K.M., Myers, R.M., Bonneau, R. and Littman, D.R.
Cell 151 (2): 289-303. 12 October 2012

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C., Rom, A., Franke, V., Imami, K., Arrey, G., Terne, M., Woehler, A., Akalin, A., Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Genetic identification of medullary neurons underlying congenital hypoventilation.
Cui, K., Xia, Y., Patnaik, A., Salivara, A., Lowenstein, E.D., Isik, E.G., Knorz, A.L., Airaghi, L., Crotti, M., Garratt, A.N., Meng, F., Schmitz, D., Studer, M., Rijli, F.M., Nothwang, H.G., Rost, B.R., Strauß, U. and Hernandez-Miranda, L.R.
Science Advances 10 (25): eadj0720. 21 June 2024

Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle.
Czajkowski, M.T., Rassek, C., Lenhard, D., Bröhl, D. and Birchmeier, C.
Developmental Biology 395 (2): 307-3016. 15 November 2014

Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways.
D'Autreaux, F., Coppola, E., Hirsch, M.R., Birchmeier, C. and Brunet, J.F.
Proceedings of the National Academy of Sciences of the United States of America 108 (50): 20018-20023. 13 December 2011

A medullary centre for lapping in mice.
Dempsey, B., Sungeelee, S., Bokiniec, P., Chettouh, Z., Diem, S., Autran, S., Harrell, E.R., Poulet, J.F.A., Birchmeier, C., Carey, H., Genovesio, A., McMullan, S., Goridis, C., Fortin, G. and Brunet, J.F.
Nature Communications 12 : 6307. 2 November 2021

An executive center for the intake of liquids.
Dempsey, B., Sungeelee, S., Bokiniec, P., Chettouh, Z., Diem, S., Autran, S., Harrell, E.R., Poulet, J.F.A., Birchmeier, C., Carrey, H., Genovesio, A., McMullan, S., Goridis, C., Fortin, G. and Brunet, J.F.
bioRxiv : 2021.07.02.450862. 4 July 2021

β-secretase BACE1 is required for normal cochlear function.
Dierich, M., Hartmann, S., Dietrich, N., Moeser, P., Brede, F., Johnson Chacko, L., Tziridis, K., Schilling, A., Krauss, P., Hessler, S., Karch, S., Schrott-Fischer, A., Blumer, M., Birchmeier, C., Oliver, D., Moser, T., Schulze, H., Alzheimer, C., Leitner, M.G. and Huth, T.
Journal of Neuroscience 39 (45): 9013-9027. 6 November 2019

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S., Company, C., Song, K., Lowenstein, E.D., Riedel, L., Birchmeier, C., Gargiulo, G. and Zampieri, N.
Nature Communications 13 (1): 6867. 11 November 2022

Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons.
Dubreuil, V., Thoby-Brisson, M., Rallu, M., Persson, K., Pattyn, A., Birchmeier, C., Brunet, J.F., Fortin, G. and Goridis, C.
Journal of Neuroscience 29 (47): 14836-14846. 25 November 2009

Differential expression of neurotrophin receptors during renal development.
Durbeej, M., Soederstroem, S., Ebendal, T., Birchmeier, C. and Ekblom, P.
Development 119 (4): 977-989. December 1993

Parasympathetic neurons originate from nerve-associated peripheral glial progenitors.
Dyachuk, V., Furlan, A., Shahidi, M.K., Giovenco, M., Kaukua, N., Konstantinidou, C., Pachnis, V., Memic, F., Marklund, U., Müller, T., Birchmeier, C., Fried, K., Ernfors, P. and Adameyko, I.
Science 345 (6192): 82-87. 4 July 2014

Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities.
Ebel, P., Vom Dorp, K., Petrasch-Parwez, E., Zlomuzica, A., Kinugawa, K., Mariani, J., Minich, D., Ginkel, C., Welcker, J., Degen, J., Eckhardt, M., Dere, E., Doermann, P. and Willecke, K.
Journal of Biological Chemistry 288 (29): 21433-21447. 19 July 2013

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.
Espinosa-Medina, I., Jevans, B., Boismoreau, F., Chettouh, Z., Enomoto, H., Müller, T., Birchmeier, C., Burns, Alan J and Brunet, J.F.
Proceedings of the National Academy of Sciences of the United States of America 114 (45): 11980-11985. 7 November 2017

Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis.
Esteves de Lima, J., Bonnin, M.A., Birchmeier, C. and Duprez, D.
eLife 5 : e15593. 24 August 2016

Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of Basal progenitors in the developing mouse neocortex.
Farkas, L.M., Haffner, C., Giger, T., Khaitovich, P., Nowick, K., Birchmeier, C., Paeaebo, S. and Huttner, W.B.
Neuron 60 (1): 40-55. 9 October 2008

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C., Urzi, A., Vidal, R., Kunz, S., Ruffault, P.L., Kabuss, L., Hube, I., Gazzerro, E., Birchmeier, C., Spuler, S., Sauer, S. and Gouti, M.
Cell Stem Cell 26 (2): 172-186. 6 February 2020

BACE1 dependent neuregulin processing: review.
Fleck, D., Garratt, A.N., Haass, C. and Willem, M.
Current Alzheimer Research 9 (2): 178-183. February 2012

The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1.
Freese, C., Garratt, A.N., Fahrenholz, F. and Endres, K.
FEBS Journal 276 (6): 1568-1580. March 2009

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy.
Frezel, N., Ranucci, M., Foster, E., Wende, H., Pelczar, P., Mendes, R., Ganley, R.P., Werynska, K., d'Aquin, S., Beccarini, C., Birchmeier, C., Zeilhofer, H.U. and Wildner, H.
Cell Reports 42 (4): 112295. 21 March 2023

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.
Fricker, F.R., Antunes-Martins, A., Galino, J., Paramsothy, R., La Russa, F., Perkins, J., Goldberg, R., Brelstaff, J., Zhu, N., McMahon, S.B., Orengo, C., Garratt, A.N., Birchmeier, C. and Bennett, D.L.
Brain 136 (Pt 7): 2279-2297. July 2013

Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood.
Fricker, F.R., Lago, N., Balarajah, S., Tsantoulas, C., Tanna, S., Zhu, N., Fageiry, S.K., Jenkins, M., Garratt, A.N., Birchmeier, C. and Bennett, D.L.
Journal of Neuroscience 31 (9): 3225-3233. 2 March 2011

Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.
Fricker, F.R., Zhu, N., Tsantoulas, C., Abrahamsen, B., Nassar, M.A., Thakur, M., Garratt, A.N., Birchmeier, C., McMahon, S.B., Wood, J.N. and Bennett, D.L.
Journal of Neuroscience 29 (24): 7667-7678. 17 June 2009

"To erb-B or not to erb-B..." Neuregulin-1/ErbB signaling in heart development and function.
Garratt, A.N.
Journal of Molecular and Cellular Cardiology 41 (2): 215-218. August 2006

A dual role of erbB2 in myelination and in expansion of the Schwann cell precursor pool.
Garratt, A.N., Voiculescu, O., Topilko, P., Charnay, P. and Birchmeier, C.
Journal of Cell Biology 148 (5): 1035-1046. 6 March 2000

Targeting MET in cancer: rationale and progress.
Gherardi, E., Birchmeier, W., Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice.
Giebeler, A., Boekschoten, M.V., Klein, C., Borowiak, M., Birchmeier, C., Gassler, N., Wasmuth, H.E., Mueller, M., Trautwein, C. and Streetz, K.L.
Gastroenterology 137 (1): 297-308. July 2009

The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
Gierl, M.S., Karoulias, N., Wende, H., Strehle, M. and Birchmeier, C.
Genes & Development 20 (17): 2465-2478. 1 September 2006

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M., Yu, Y., Liang, L., Vuralli, D., Froehler, S., Kuehnen, P., Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J., Jia, S., Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7 (5): e602. May 2019

Notch signaling is essential for ventricular chamber development.
Grego-Bessa, J., Luna-Zurita, L., del Monte, G., Bolos, V., Melgar, P., Arandilla, A., Garratt, A.N., Zang, H., Mukouyama, Y.S., Chen, H., Shou, W., Ballestar, E., Esteller, M., Rojas, A., Perez-Pomares, J.M. and de la Pompa, J.L.
Developmental Cell 12 (3): 415-429. March 2007

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence.
Griger, J., Schneider, R., Lahmann, I., Schöwel, V., Keller, C., Spuler, S., Nazare, M. and Birchmeier, C.
eLife 6 : e21552. 2 May 2017

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
Grigoryan, T., Stein, S., Qi, J., Wende, H., Garratt, A.N., Nave, K.A., Birchmeier, C. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 110 (45): 18174-18179. 5 November 2013

The tyrosine phosphatase Shp2 in development and cancer.
Grossmann, K.S., Rosario, M., Birchmeier, C. and Birchmeier, W.
Advances in Cancer Research 106 : 53-89. 2010

The tyrosine phosphatase Shp2 (PTPN11) directs neuregulin-1/ErbB signaling throughout schwann cell development.
Grossmann, K.S., Wende, H., Paul, F.E., Cheret, C., Garratt, A.N., Zurborg, S., Feinberg, K., Besser, D., Schulz, H., Peles, E., Selbach, M., Birchmeier, W. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (39): 16704-16709. 29 September 2009

CO(2) in the spotlight.
Hernandez-Miranda, L.R. and Birchmeier, C.
eLife 4 : e08086. 13 May 2015

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice.
Hernandez-Miranda, L.R., Ibrahim, D.M., Ruffault, P.L., Larrosa, M., Balueva, K., Müller, T., de Weerd, W., Stolte-Dijkstra, I., Hostra, R.M.W., Brunet, J.F., Fortin, G., Mundlos, S. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 115 (51): 13021-13026. 18 December 2018

The dorsal spinal cord and hindbrain: from developmental mechanisms to functional circuits.
Hernandez-Miranda, L.R., Müller, T. and Birchmeier, C.
Developmental Biology 432 (1): 34-42. 1 December 2017

Genetic identification of a hindbrain nucleus essential for innate vocalization.
Hernandez-Miranda, L.R., Ruffault, P.L., Bouvier, J.C., Murray, A.J., Morin-Surun, M.P., Zampieri, N., Cholewa-Waclaw, J.B., Ey, E., Brunet, J.F., Champagnat, J., Fortin, G. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 114 (30): 8095-8100. 25 July 2017

A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice.
Hesse, M., Grund, C., Herrmann, H., Broehl, D., Franz, T., Omary, M.B. and Magin, T.M.
Experimental Cell Research 313 (14): 3127-3140. 15 August 2007

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling.
Hori, K., Cholewa-Waclaw, J., Nakada, Y., Glasgow, S.M., Masui, T., Henke, R.M., Wildner, H., Martarelli, B., Beres, T.M., Epstein, J.A., Magnuson, M.A., Macdonald, R.J., Birchmeier, C. and Johnson, J.E.
Genes & Development 22 (2): 166-178. 15 January 2008

Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J., Vogel, R., Brinkmann, V., Erdmann, B., Birchmeier, C. and Birchmeier, W.
Journal of Cell Biology 148 (3): 567-578. 7 February 2000

Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors.
Humphries, J.D., Schofield, N.R., Mostafavi-Pour, Z., Green, L.J., Garratt, A.N., Mould, A.P. and Humphries, M.J.
Journal of Biological Chemistry 280 (11): 10234-10243. 18 March 2005

Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.
Jacob, J., Storm, R., Castro, D.S., Milton, C., Pla, P., Guillemot, F., Birchmeier, C. and Briscoe, J.
Development 136 (14): 2477-2485. July 2009

Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1.
Jia, S., Wildner, H. and Birchmeier, C.
Developmental Biology 408 (1): 90-98. 1 December 2015

Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.
Jia, S., Ivanov, A., Blasevic, D., Müller, T., Purfürst, B., Sun, W., Chen, W., Poy, M.N., Rajewsky, N. and Birchmeier, C.
EMBO Journal 34 (10): 1417-1433. 12 May 2015

Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development.
John, A., Brylka, H., Wiegreffe, C., Simon, R., Liu, P., Juettner, R., Crenshaw, E.B., Luyten, F.P., Jenkins, N.A., Copeland, N.G., Birchmeier, C. and Britsch, S.
Development 139 (10): 1831-1841. 15 May 2012

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M., Franke, V., Brandt, B., Lowenstein, E.D., Schöwel, V., Spuler, S., Akalin, A. and Birchmeier, C.
Nature Communications 11 : 6375. 11 December 2020

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M., Wende, H., Walcher, J., Kühnemund, J., Cheret, C., Kempa, S., McShane, E., Selbach, M., Lewin, G.R. and Birchmeier, C.
Genes & Development 32 (9-10): 645-657. 10 May 2018

Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation.
Kim, M., Zhang, Y. and Birchmeier, C.
bioRxiv : 2020.12.22.424062. 22 December 2020

SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta.
Kirchenwitz, M., Stahnke, S., Prettin, S., Borowiak, M., Menke, L., Sieben, C., Birchmeier, C., Rottner, K., Stradal, T.E.B. and Steffen, A.
Cells 11 (10): 1648. 16 May 2022

Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi, V., Peng, S., Klironomos, F., Munschauer, M., Kastelic, N., Chakraborty, T., Schoeler, K., Derudder, E., Martella, M., Mastrobuoni, G., Hernandez-Miranda, L.R., Lahmann, I., Kocks, C., Birchmeier, C., Kempa, S., Quintanilla-Martinez de Fend, L., Landthaler, M., Rajewsky, N. and Rajewsky, K.
Genes & Development 33 : 23-24. 7 November 2019

Uncoupling of PI3K from ErbB3 impairs mammary gland development but does not impact on ErbB2-induced mammary tumorigenesis.
Lahlou, H., Mueller, T., Sanguin-Gendreau, V., Birchmeier, C. and Muller, W.J.
Cancer Research 72 (12): 3080-3090. 15 June 2012

Visualizing MyoD oscillations in muscle stem cells.
Lahmann, I. and Birchmeier, C.
Methods in Molecular Biology 2640 : 259-276. 2023

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I., Bröhl, D., Zyrianova, T., Isomura, A., Czajkowski, M.T., Kapoor, V., Griger, J., Ruffault, P.L., Mademtzoglou, D., Zammit, P.S., Wunderlich, T., Spuler, S., Kühn, R., Preibisch, S., Wolf, J., Kageyama, R. and Birchmeier, C.
Genes & Development 33 (9-10): 524-535. 1 May 2019

Met and Cxcr4 cooperate to protect skeletal muscle stem cells against inflammation-induced damage during regeneration.
Lahmann, I., Griger, J., Chen, J.S., Zhang, Y., Schülke, M. and Birchmeier-Kohler, C.
eLife 10 : e57356. 5 August 2021

An oscillatory network controlling self-renewal of skeletal muscle stem cells.
Lahmann, I., Zhang, Y., Baum, K., Wolf, J. and Birchmeier, C.
Experimental Cell Research 409 (2): 112933. 15 December 2021

Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium.
Lai, D., Forrai, A., Liu, X., Wolstein, O., Michalicek, J., Ahmed, I., Garratt, A.N., Birchmeier, C., Zhou, M., Hartley, L., Robb, L., Feneley, M.P., Fatkin, D. and Harvey, R.P.
Circulation Research 107 (6): 715-727. 17 September 2010

Mafa-dependent GABAergic activity promotes mouse neonatal apneas.
Lecoin, L., Dempsey, B., Garancher, A., Bourane, S., Ruffault, P.L., Morin-Surun, M.P., Rocques, N., Goulding, M., Eychène, A., Pouponnot, C., Fortin, G. and Champagnat, J.
Nature Communications 13 (1): 3284. 7 June 2022

Technologies for profiling the impact of genomic variants on transcription factor binding.
Leiz, J., Rutkiewicz, M., Birchmeier, C., Heinemann, U. and Schmidt-Ott, K.M.
Medizinische Genetik 33 (2): 147-155. 14 August 2021

Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action.
Loos, M., Mueller, T., Gouwenberg, Y., Wijnands, R., van der Loo, R.J., Birchmeier, C., Smit, A.B. and Spijker, S.
Biological Psychiatry 76 (8): 648-655. 15 October 2014

Diversity in the lab makes me a better scientist.
Lowenstein, E.
Scientific American 320 (1): 8. January 2019

Regulation of early cerebellar development.
Lowenstein, E., Cui, K. and Hernandez-Miranda, L.R.
FEBS Journal 290 (11): 2786-2804. June 2022

Molecular characterization of nodose ganglia development reveals a novel population of Phox2b+ glial progenitors in mice.
Lowenstein, E.D., Misios, A., Buchert, S. and Ruffault, P.L.
Journal of Neuroscience 44 (28): e1441232024. 10 July 2024

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
Lowenstein, E.D., Ruffault, P.L., Misios, A., Osman, K.L., Li, H., Greenberg, R.S., Thompson, R., Song, K., Dietrich, S., Li, X., Vladimirov, N., Woehler, A., Brunet, J.F., Zampieri, N., Kühn, R., Liberles, S.D., Jia, S., Lewin, G.R., Rajewsky, N., Lever, T.E. and Birchmeier, C.
Neuron 111 (14): 2184-2200.e7. 19 July 2023

Olig3 regulates early cerebellar development.
Lowenstein, E.D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A.E., Epifanova, E., Bladt, F., Isik, E.G., Buchert, S., Jia, S., Tarabykin, V. and Hernandez-Miranda, L.R.
eLife 10 : e64684. 16 February 2021

Olig3 acts as a master regulator of cerebellar development.
Lowenstein, E.D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A.E., Epifanova, E., Bladt, F., Isik, E.G., Jia, S., Tarabykin, V. and Hernandez-Miranda, L.R.
bioRxiv : 2020.10.10.334615. 10 October 2020

Human satellite cells have regenerative capacity and are genetically manipulable.
Marg, A., Escobar, H., Gloy, S., Kufeld, M., Zacher, J., Spuler, A., Birchmeier, C., Izsvák, Z. and Spuler, S.
Journal of Clinical Investigation 124 (10): 4257-4265. 1 October 2014

Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Marg, A., Escobar Fernandez, H., Karaiskos, N., Grunwald, S.A., Metzler, E., Kieshauer, J., Sauer, S., Pasemann, D., Malfatti, E., Mompoint, D., Quijano-Roy, S., Boltengagen, A., Schneider, J., Schülke, M., Kunz, S., Carlier, R., Birchmeier, C., Amthor, H., Spuler, A., Kocks, C., Rajewsky, N. and Spuler, S.
Nature Communications 10 (1): 5776. 18 December 2019

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C., Lahmann, I., Kunz, S., Jonas, W., Melo, A.A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Blüher, M., Olschowski, H., Kompa, J., Brügger, B., Müller, D.N., Haucke, V., Schürmann, A., Birchmeier, C. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 117 (13): 7471-7481. 31 March 2020

eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization.
Matthaeus, C., Lian, X., Kunz, S., Lehmann, M., Zhong, C., Bernert, C., Lahmann, I., Müller, D.N., Gollasch, M. and Daumke, O.
PLoS ONE 14 (10): e0223620. 10 October 2019

Multiple essential functions of neuregulin in development.
Meyer, D. and Birchmeier, C.
Nature 378 (6555): 386-390. 23 November 1995

Isoform specific expression and function of neuregulin.
Meyer, D., Yamaai, T., Garratt, A., Riethmacher-Sonnenberg, E., Kane, D., Theill, L.E. and Birchmeier, C.
Development 124 (18): 3575-3586. September 1997

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K., Kirchner, M., Uyar, B., Cheng, J.Y., Russo, G., Hernandez-Miranda, L.R., Szymborska, A., Zauber, H., Rudolph, I.M., Willnow, T.E., Akalin, A., Haucke, V., Gerhardt, H., Birchmeier, C., Kühn, R., Krauss, M., Diecke, S., Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

Nociceptive tuning by stem cell factor/c-Kit signaling.
Milenkovic, N., Frahm, C., Gassmann, M., Griffel, C., Erdmann, B., Birchmeier, C., Lewin, G.R. and Garratt, A.N.
Neuron 56 (5): 893-906. 6 December 2007

240th ENMC workshop: The involvement of skeletal muscle stem cells in the pathology of muscular dystrophies 25–27 January 2019, Hoofddorp, The Netherlands.
Morgan, J., Butler-Browne, G., Muntoni, F. and Patel, K.
Neuromuscular Disorders 29 (9): 704-715. 2019

Neural development.
Mueller, T.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1258-1266. ISBN 3-540-44244-8 2006

Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons.
Müller, T., Braud, S., Jüttner, R., Voigt, B.C., Paulick, K., Sheean, M.E., Klisch, C., Gueneykaya, D., Rathjen, F.G., Geiger, J.R.P., Poulet, J.F.A. and Birchmeier, C.
EMBO Journal 37 (17): e98858. 3 September 2018

The homeodomain factor Lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord.
Müller, T., Brohmann, H., Pierani, A., Heppenstall, P.A., Lewin, G.R., Jessell, T.M. and Birchmeier, C.
Neuron 34 (4): 551-562. 16 May 2002

Nrg1/ErbB signaling networks in Schwann cell development and myelination.
Newbern, J. and Birchmeier, C.
Seminars in Cell & Developmental Biology 21 (9): 922-988. December 2010

Defining orphan conditions in the context of the European orphan regulation: challenges and evolution.
O'Connor, D.J., Sheean, M.E., Hofer, M.P., Tsigkos, S., Mariz, S., Fregonese, L., Larsson, K., Hivert, V., Westermark, K., Naumann-Winter, F., Stoyanova-Beninska, V., Barišić, I., Capovilla, G., Magrelli, A. and Sepodes, B.
Nature Reviews Drug Discovery 18 (7): 479-480. July 2019

The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte coupling in mice.
Pelz, L., Dossou, L., Kompier, N., Jüttner, R., Siemonsmeier, G., Meyer, N., Lowenstein, E.D., Lahmann, I., Kettenmann, H., Birchmeier, C. and Rathjen, F.G.
eNeuro 11 (3): ENEURO.0283-23.2024. 22 February 2024 (In Press)

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M., Glažar, P., Hernandez-Miranda, L.R., Memczak, S., Wolf, S.A., Rybak-Wolf, A., Filipchyk, A., Klironomos, F., Cerda Jara, C.A., Fenske, P., Trimbuch, T., Zywitza, V., Plass, M., Schreyer, L., Ayoub, S., Kocks, C., Kühn, R., Rosenmund, C., Birchmeier, C. and Rajewsky, N.
Science 357 (6357): eaam8526. 22 September 2017

Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system.
Potzner, M.R., Griffel, C., Luetjen-Drecoll, E., Boesl, M.R., Wegner, M. and Sock, E.
Molecular and Cellular Biology 27 (15): 5316-5326. August 2007

TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction.
Ragancokova, D., Rocca, E., Oonk, A.M.M., Schulz, H., Rohde, E., Bednarsch, J., Feenstra, I., Pennings, R.J.E., Wende, H. and Garratt, A.N.
Journal of Clinical Investigation 124 (3): 1214-1227. 3 March 2014

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.
Ravindran, E., Hu, H., Yuzwa, S.A., Hernandez-Miranda, L.R., Kraemer, N., Ninnemann, O., Musante, L., Boltshauser, E., Schindler, D., Hübner, A., Reinecker, H.-C., Ropers, H.-H., Birchmeier, C., Miller, F.D., Wienker, T.F., Hübner, C. and Kaindl, A.M.
PLoS Genetics 13 (4): e1006746. 28 April 2017

Die Funktion des Transkriptionsfaktors Olig3 in der Entwicklung des Hirnstamms [The function of the transcription factor Olig3 in the development of the hindbrain].
Reuter, K.
UNSPECIFIED thesis, UNSPECIFIED. 14 July 2006

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor.
Riethmacher, D., Sonnenberg-Riethmacher, E., Brinkmann, V., Yamaai, T., Lewin, G.R. and Birchmeier, C.
Nature 389 (6652): 725-730. 16 October 1997

BMP signaling controls muscle mass.
Sartori, R., Schirwis, E., Blaauw, B., Bortolanza, S., Zhao, J., Enzo, E., Stantzou, A., Mouisel, E., Toniolo, L., Ferry, A., Stricker, S., Goldberg, A.L., Dupont, S., Piccolo, S., Amthor, H. and Sandri, M.
Nature Genetics 45 (11): 1309-1318. November 2013

Neuregulin-1 mutant mice indicate motor and sensory deficits, indeed few references for schizophrenia endophenotype model.
Schneider, S., Götz, K., Birchmeier, C., Schwegler, H. and Roskoden, T.
Behavioural Brain Research 322 (Pt A): 177-185. 30 March 2017

Nonclinical data supporting orphan medicinal product designations in the area of rare infectious diseases.
Sheean, M.E., Malikova, E., Duarte, D., Capovilla, G., Fregonese, L., Hofer, M., Magrelli, A., Mariz, S., Mendez-Hermida, F., Nistico, R., Leest, T., Sipsas, N.V., Tsigkos, S., Vitezic, D., Larsson, K., Sepodes, B. and Stoyanova-Beninska, V.
Drug Discovery Today 25 (2): 274-291. February 2020

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E., McShane, E., Cheret, C., Walcher, J., Müller, T., Wulf-Goldenberg, A., Hoelper, S., Garratt, A.N., Krüger, M., Rajewsky, K., Meijer, D., Birchmeier, W., Lewin, G.R., Selbach, M. and Birchmeier, C.
Genes & Development 28 (3): 290-303. 1 February 2014

Nonclinical data supporting orphan medicinal product designations: lessons from rare neurological conditions.
Sheean, M.E., Stoyanova-Beninska, V., Capovilla, G., Duarte, D., Hofer, M.P., Hoffmann, M., Magrelli, A., Mariz, S., Tsigkos, S., Shaili, E., Polsinelli, B., Ricciardi, M., Bonelli, M., Balabanov, P., Larsson, K. and Sepodes, B.
Drug Discovery Today 23 (1): 26-48. January 2018

Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain.
Sieber, M.A., Storm, R., Martinez-de-la-Torre, M., Mueller, T., Wende, H., Reuter, K., Vasyutina, E. and Birchmeier, C.
Journal of Neuroscience 27 (18): 4902-4909. 2 May 2007

Recessive mutations in PCBD1 cause a new type of early-onset diabetes.
Simaite, D., Kofent, J., Gong, M., Rüschendorf, F., Jia, S., Arn, P., Bentler, K., Ellaway, C., Kühnen, P., Hoffmann, G.F., Blau, N., Spagnoli, F.M., Hübner, N. and Raile, K.
Diabetes 63 (10): 3557-3564. October 2014

A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis.
Simon, R., Brylka, H., Schwegler, H., Venkataramanappa, S., Andratschke, J., Wiegreffe, C., Liu, P., Fuchs, E., Jenkins, N.A., Copeland, N.G., Birchmeier, C. and Britsch, S.
EMBO Journal 31 (13): 2922-2936. 15 May 2012

Mutations in MYO1H cause a recessive form of central hypoventilation with autonomic dysfunction.
Spielmann, M., Hernandez-Miranda, L.R., Ceccherini, I., Weese-Mayer, D.E., Kragesteen, B.K., Harabula, I., Krawitz, P., Birchmeier, C., Leonard, N. and Mundlos, S.
Journal of Medical Genetics 54 (11): 754-761. November 2017

BMP signaling regulates satellite cell dependent postnatal muscle growth.
Stantzou, A., Schirwis, E., Swist, S., Alonso-Martin, S., Polydorou, I., Zarrouki, F., Mouisel, E., Beley, C., Julien, A., Le Grand, F., Garcia, L., Colnot, C., Birchmeier, C., Braun, T., Schuelke, M., Relaix, F. and Amthor, H.
Development 144 (15): 2737-2747. 1 August 2017

The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei.
Storm, R., Cholewa-Waclaw, J., Reuter, K., Broehl, D., Sieber, M., Treier, M., Mueller, T. and Birchmeier, C.
Development 136 (2): 295-305. January 2009

Therapeutic potential of N-acetyl-glucagon-like peptide-1 in primary motor neuron cultures derived from non-transgenic and SOD1-G93A ALS mice.
Sun, H., Knippenberg, S., Thau, N., Ragancokova, D., Koerner, S., Huang, D., Dengler, R., Doehler, K. and Petri, S.
Cellular and Molecular Neurobiology 33 (3): 347-357. April 2013

Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.
Sury, M.D., McShane, E., Hernandez-Miranda, L.R., Birchmeier, C. and Selbach, M.
Molecular & Cellular Proteomics 14 (1): 50-65. 1 January 2015

Haploinsufficiency of Insm1 impairs postnatal baseline β-cell mass.
Tao, W., Zhang, Y., Ma, L., Deng, C., Duan, H., Liang, X., Liao, R., Lin, S., Nie, T., Chen, W., Wang, C., Birchmeier, C. and Jia, S.
Diabetes 67 (12): 2615-2625. December 2018

Identification of V0g propriospinal neurons and their role in locomotor control.
Toscano, E., Giomi, M., Evtushenko, N., Santuz, A., Lowenstein, E.D., Birchmeier, C. and Zampieri, N.
bioRxiv : 2025.02.11.636221. 12 February 2025

Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling.
Trimbuch, T., Beed, P., Vogt, J., Schuchmann, S., Maier, N., Kintscher, M., Breustedt, J., Schuelke, M., Streu, N., Kieselmann, O., Brunk, I., Laube, G., Strauss, U., Battefeld, A., Wende, H., Birchmeier, C., Wiese, S., Sendtner, M., Kawabe, H., Kishimoto-Suga, M., Brose, N., Baumgart, J., Geist, B., Aoki, J., Savaskan, N.E., Braeuer, A.U., Chun, J., Ninnemann, O., Schmitz, D. and Nitsch, R.
Cell 138 (6): 1222-12235. 18 September 2009

Establishing rarity in the context of orphan medicinal product designation in the European Union.
Tsigkos, S., Hoffer, M.P., Sheean, M.E., Mariz, S., Larsson, K., Naumann-Winter, F., Fregonese, L. and Sepodes, B.
Drug Discovery Today 23 (3): 681-686. March 2018

Neural crest cell lineage restricts skeletal muscle progenitor cell differentiation through Neuregulin1-ErbB3 signaling.
Van Ho, A.T., Hayashi, S., Broehl, D., Aurade, F., Rattenbach, R. and Relaix, F.
Developmental Cell 21 (2): 273-287. 16 August 2011

The development of migrating muscle precursor cells.
Vasyutina, E. and Birchmeier, C.
Anatomy and Embryology 211 (Suppl.): S37-S41. December 2006

Notch function in myogenesis.
Vasyutina, E., Lenhard, D.C. and Birchmeier, C.
Cell Cycle 6 (12): 1451-1454. 15 June 2007

RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells.
Vasyutina, E., Lenhard, D.C., Wende, H., Erdmann, B., Epstein, J.A. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 104 (11): 4443-4448. 13 March 2007

The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse.
Vasyutina, E., Martarelli, B., Brakebusch, C., Wende, H. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 106 (22): 8935-8940. 2 June 2009

CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells.
Vasyutina, E., Stebler, J., Brand-Saberi, B., Schulz, S., Raz, E. and Birchmeier, C.
Genes & Development 19 (18): 2187-2198. 15 September 2005

Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors.
Welcker, J.E., Hernandez-Miranda, L.R., Paul, F.E., Jia, S., Ivanov, A., Selbach, M. and Birchmeier, C.
Development 140 (24): 4947-4958. December 2013

The transcription factor c-Maf in sensory neuron development.
Wende, H., Lechner, S.G. and Birchmeier, C.
Transcription 3 (6): 285-289. November 2012

The transcription factor c-Maf controls touch receptor development and function.
Wende, H., Lechner, S.G., Cheret, C., Bourane, S., Kolanczyk, M.E., Pattyn, A., Reuter, K., Munier, F.L., Carroll, P., Lewin, G.R. and Birchmeier, C.
Science 335 (6074): 1373-1376. 16 March 2012

Bcl11a (Ctip1) controls migration of cortical projection neurons through regulation of Sema3c.
Wiegreffe, C., Simon, R., Peschkes, K., Kling, C., Strehle, M., Cheng, J., Srivatsa, S., Liu, P., Jenkins, N.A., Copeland, N.G., Tarabykin, V. and Britsch, S.
Neuron 87 (2): 311-325. 15 July 2015

Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage.
Wildner, H., Gierl, M.S., Strehle, M., Pla, P. and Birchmeier, C.
Development 135 (3): 473-81. February 2008

dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development.
Wildner, H., Mueller, T., Cho, S.H., Broehl, D., Cepko, C.L., Guillemot, F. and Birchmeier, C.
Development 133 (11): 2105-2113. 1 June 2006

Genome-wide expression analysis of ptf1a- and ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity.
Wildner, H., Das Gupta, R., Bröhl, D., Heppenstall, P.A., Zeilhofer, H.U. and Birchmeier, C.
Journal of Neuroscience 33 (17): 7299-7307. 24 April 2013

Control of peripheral nerve myelination by the β-secretase BACE1.
Willem, M., Garratt, A.N., Novak, B., Citron, M., Kaufmann, S., Rittger, A., Destrooper, B., Saftig, P., Birchmeier, C. and Haass, C.
Science 314 (5799): 664-666. 27 October 2006

Genetische Analyse des Tyrosinkinase-Rezeptors ErbB2.
Woldeyesus, M.T.
UNSPECIFIED thesis, UNSPECIFIED. 14 February 2001

Post-transcriptional regulation of the let-7 microRNA during neural cell specification.
Wulczyn, F.G., Smirnova, L., Rybak, A., Brandt, C., Kwidzinski, E., Ninnemann, O., Strehle, M., Seiler, A., Schumacher, S. and Nitsch, R.
FASEB Journal 21 (2): 415-426. February 2007

SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis.
Wurmser, M., Chaverot, N., Madani, R., Sakai, H., Negroni, E., Demignon, J., Saint-Pierre, B., Mouly, V., Amthor, H., Tapscott, S., Birchmeier, C., Tajbakhsh, S., Le Grand, F., Sotiropoulos, A. and Maire, P.
Development 147 (19): dev185975. 9 October 2020

Transcription factors regulating the specification of brainstem respiratory neurons.
Xia, Y., Cui, K., Alonso, A., Lowenstein, E.D. and Hernandez-Miranda, L.R.
Frontiers in Molecular Neuroscience 15 : 1072475. 29 November 2022

Predominant patterns of splicing evolution on human, chimpanzee, and macaque evolutionary lineages.
Xiong, J., Xi, J., Ditsiou, A., Gao, Y., Sun, J., Lowenstein, E.D., Huang, S. and Khaitovich, P.
Human Molecular Genetics 27 (8): 1474-1485. 15 April 2018

Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities.
Xu, Y., Lopes, C., Wende, H., Guo, Z., Cheng, L., Birchmeier, C. and Ma, Q.
Journal of Neuroscience 33 (37): 14738-14748. 11 September 2013

Antagonistic regulation of p57(kip2) by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest.
Zalc, A., Hayashi, S., Auradé, F., Bröhl, D., Chang, T., Mademtzoglou, D., Mourikis, P., Yao, Z., Cao, Y., Birchmeier, C. and Relaix, F.
Development 141 (14): 2780-2790. July 2014

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting.
Zanders, L., Kny, M., Hahn, A., Schmidt, S., Wundersitz, S., Todiras, M., Lahmann, I., Bandyopadhyay, A., Wollersheim, T., Kaderali, L., Luft, F.C., Birchmeier, C., Weber-Carstens, S. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 13 (1): 713-727. February 2021

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A., van den Bruck, D., Ciolli Mattioli, C., Franke, V., Imami, K., McShane, E., Moreno-Estelles, M., Calviello, L., Filipchyk, A., Peguero-Sanchez, E., Müller, T., Woehler, A., Birchmeier, C., Merino, E., Rajewsky, N., Ohler, U., Mazzoni, E.O., Selbach, M., Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells.
Zhang, Y., Lahmann, I., Baum, K., Shimojo, H., Mourikis, P., Wolf, J., Kageyama, R. and Birchmeier, C.
Nature Communications 12 (1): 1318. 26 February 2021

Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations.
Zhao, W., Bohleber, S., Schmidt, H., Seeher, S., Howard, M.T., Braun, D., Arndt, S., Reuter, U., Wende, H., Birchmeier, C., Fradejas-Villar, N. and Schweizer, U.
Journal of Biological Chemistry 294 (39): 14185-14200. 27 September 2019

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S., Hübner, N., Chien, K.R., Birchmeier, C. and Garratt, A.N.
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Birol, Melissa (BIMSB)

The C-terminus of α-synuclein regulates its dynamic cellular internalization by neurexin 1β.
Birol, M., Douzoglou Muñoz, I.I. and Rhoades, E.
Molecular Biology of the Cell 34 (13): br21. 1 December 2023

Structure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins.
Birol, M. and Echalier, A.
Current Protein & Peptide Science 15 (5): 504-517. 2014

Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer.
Birol, M., Enchev, R.I., Padilla, A., Stengel, F., Aebersold, R., Betzi, S., Yang, Y., Hoh, F., Peter, M., Dumas, C. and Echalier, A.
PLoS ONE 9 (8): e105688. 21 August 2014

Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid.
Birol, M., Kumar, S., Rhoades, E. and Miranker, A.D.
Nature Communications 9 (1): 1312. 3 April 2018

Untangling the conformational polymorphism of disordered proteins associated with neurodegeneration at the single-molecule level.
Birol, M. and Melo, A.M.
Frontiers in Molecular Neuroscience 12 : 309. 10 January 2020

Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein.
Birol, M., Wojcik, S.P., Miranker, A.D. and Rhoades, E.
PLoS Biology 17 (6): e3000318. 18 June 2019

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
Echalier, A., Pan, Y., Birol, M., Tavernier, N., Pintard, L., Hoh, F., Ebel, C., Galophe, N., Claret, F.X. and Dumas, C.
Proceedings of the National Academy of Sciences of the United States of America 110 (4): 1273-1278. 22 January 2013

IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies.
Fung, H.Y.J., Birol, M. and Rhoades, E.
Current Opinion in Structural Biology 49 : 36-43. April 2018

Deuterated oxazines are bright near-infrared fluorophores for mitochondrial imaging and single molecule spectroscopy.
Gatin-Fraudet, B., Seifert, J., Sarach, K., Olesen, C.H., Birke, R., Milles, S., Birol, M., Lehmann, M. and Broichhagen, J.
Chemical Communications 61 (17): 3540-3543. 20 February 2025

Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin.
Kumar, S., Birol, M. and Miranker, A.D.
Chemical Communications 52 (38): 6391-6394. 11 May 2016

Foldamer-mediated manipulation of a pre-amyloid toxin.
Kumar, S., Birol, M., Schlamadinger, D.E., Wojcik, S.P., Rhoades, E. and Miranker, A.D.
Nature Communications 7 : 11412. 25 April 2016

Routing of Kv7.1 to endoplasmic reticulum plasma membrane junctions.
Serrano-Novillo, C., Estadella, I., Navarro-Pérez, M., Oliveras, A., de Benito-Bueno, A., Socuéllamos, P.G., Bosch, M., Coronado, M.J., Sastre, D., Valenzuela, C., Soeller, C. and Felipe, A.
Acta Physiologica 240 (3): e14106. March 2024

Enzyme self-label-bound ATTO700 in single-molecule and super-resolution microscopy.
Trumpp, M., Oliveras, A., Gonschior, H., Ast, J., Hodson, D.J., Knaus, P., Lehmann, M., Birol, M. and Broichhagen, J.
Chemical Communications 58 (99): 13724-13727. 13 December 2022

Targeting the intrinsically disordered proteome using small-molecule ligands.
Wójcik, S., Birol, M., Rhoades, E., Miranker, A.D. and Levine, Z.A.
Methods in Enzymology 611 : 703-734. 2018

Blankenstein, Thomas

Early life stress regulates cardiac development through an IL4-glucocorticoid signaling balance.
Apaydin, D.C., Jaramillo, P.A.M., Corradi, L., Cosco, F., Rathjen, F.G., Kammertoens, T., Filosa, A. and Sawamiphak, S.
Cell Reports 33 (7): 108404. 17 November 2020

MHCII-independent CD4(+) T cells protect injured CNS neurons via IL-4.
Walsh, J.T., Hendrix, S., Boato, F., Smirnov, I., Zheng, J., Lukens, J.R., Gadani, S., Hechler, D., Gölz, G., Rosenberger, K., Kammertöns, T., Vogt, J., Vogelaar, C., Siffrin, V., Radjavi, A., Fernandez-Castaneda, A., Gaultier, A., Gold, R., Kanneganti, T.D., Nitsch, R., Zipp, F. and Kipnis, J.
Journal of Clinical Investigation 125 (2): 699-714. 2 February 2015

CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis.
Wolf, S.A., Steiner, B., Akpinarli, A., Kammertoens, T., Nassenstein, C., Braun, A., Blankenstein, T. and Kempermann, G.
Journal of Immunology 182 (7): 3979-3984. 1 April 2009

Boschmann, Michael (ECRC)

"suMus," a novel digital system for arm movement metrics and muscle energy expenditure.
Gerhalter, Teresa, Müller, Christina, Maron, Elke, Thielen, Markus, Schätzl, Teresa, Mähler, A., Schütte, T., Boschmann, M., Herzer, René, Spuler, S. and Gazzerro, E.
Frontiers in Physiology 14 : 1057592. 26 January 2023

Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy.
Langhans, C., Weber-Carstens, S., Schmidt, F., Hamati, J., Kny, M., Zhu, X., Wollersheim, T., Koch, S., Krebs, M., Schulz, H., Lodka, D., Saar, K., Labeit, S., Spies, C., Hubner, N., Spranger, J., Spuler, S., Boschmann, M., Dittmar, G., Butler-Browne, G., Mouly, V. and Fielitz, J.
PLoS ONE 9 (3): e92048. 20 March 2014

Metabolic, mental and immunological effects of normoxic and hypoxic training in multiple sclerosis patients: a pilot study.
Mähler, A., Balogh, A., Csizmadia, I., Klug, L., Kleinewietfeld, M., Steiniger, J., Šušnjar, U., Müller, D.N., Boschmann, M. and Paul, F.
Frontiers in Immunology 9 : 2819. November 2018

Epigallocatechin-3-gallate: a useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases.
Mähler, A., Mandel, S., Lorenz, M., Ruegg, U., Wanker, E.E., Boschmann, M. and Paul, F.
EPMA Journal 4 (1): 5. 18 February 2013

Is metabolic flexibility altered in multiple sclerosis patients?
Mähler, A., Steiniger, J., Bock, M., Brandt, A.U., Haas, V., Boschmann, M. and Paul, F.
PLoS ONE 7 (8): e43675. 28 August 2012

Metabolic response to epigallocatechin-3-gallate in relapsing-remitting multiple sclerosis: a randomized clinical trial.
Mähler, A., Steiniger, J., Bock, M., Klug, L., Parreidt, N., Lorenz, M., Zimmermann, B.F., Krannich, A., Paul, F. and Boschmann, M.
American Journal of Clinical Nutrition 101 (3): 487-495. March 2015

Increased catabolic state in spinocerebellar ataxia type 1 patients.
Mähler, A., Steiniger, J., Endres, M., Paul, F., Boschmann, M. and Doss, S.
Cerebellum 13 (4): 440-446. August 2014

Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla, T., Gollasch, B., Kuich, P.H.J.L., Klug, L., Rahn, G., Busjahn, A., Spuler, S., Boschmann, M., Kirwan, J.A., Luft, F.C. and Kempa, S.
Frontiers in Molecular Biosciences 9 : 1042231. 21 December 2022

Hypoxia differentially affects healthy men and women during a daytime nap with a dose-response relationship: a randomized, cross-over pilot study.
Riveros-Rivera, A., Penzel, T., Gunga, H.C., Opatz, O., Paul, F., Klug, L., Boschmann, M. and Mähler, A.
Frontiers in Physiology 13 : 899636. 24 May 2022

Britsch, Stefan

Biology of the neuregulin/ErbB signaling network.
Britsch, S.
Advances in Anatomy Embryology and Cell Biology 190 (190): 3-46. 2007

Introduction: Molecular control of development.
Britsch, S.
Advances in Anatomy Embryology and Cell Biology 190 (190): 1-2. 2007

Summary.
Britsch, S.
Advances in Anatomy Embryology and Cell Biology 190 (190): 46-46. 2007

The neuregulin-I/ErbB signaling system in development and disease.
Britsch, S.
Advances in Anatomy, Embryology and Cell Biology, 190 . Springer, Berlin u.a., 1-70. ISBN 978-3-540-37105-2 2007

Transgenic and knock-out animals.
Britsch, S.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1900-1903. ISBN 3-540-44244-8 2006

Tiermodelle in der biomedizinischen Forschung.
Britsch, S., Strehle, M. and Birchmeier, C.
In: Grundlagen der Molekularen Medizin. Molekulare Medizin . Springer, Berlin [u.a.], 299-339. ISBN 3-540-43207-8 1 January 2003

A transcription factor code defines nine sensory interneuron subtypes in the mechanosensory area of the spinal cord.
Del Barrio, M.G., Bourane, S., Grossmann, K.S., Schuele, R., Britsch, S., O'Leary, D.D.M. and Goulding, M.
PLoS ONE 8 (11): e77928. 4 November 2013

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S., Hübner, N., Chien, K.R., Birchmeier, C. and Garratt, A.N.
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Bullinger, Lars

Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M., Liman, T.G., Strzelecka, P.M., Kufner, A., Löwe, P., Huo, S., Stein, C.M., Piper, S.K., Tilgner, M., Sperber, P.S., Dimitriou, S., Heuschmann, P., Hablesreiter, R., Harms, C., Bullinger, L., Weber, J.E., Endres, M. and Damm, F.
Blood 141 (7): 787-799. 16 February 2023

Bunina, Daria

Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome.
Proce, R.O., Uddström, E., Steinecker, M., Wüsthoff, S., Teixeira Alves, L.G., Popp, O., Maxwell, K., Hortmann, L., Mertins, P., Landthaler, M., Bunina, D. and Hörnberg, H.
bioRxiv : 2024.12.18.628637. 20 December 2024

Böttcher, Chotima (ECRC)

Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer's disease.
Fernández Zapata, C., Giacomello, G., Spruth, E.J., Middeldorp, J., Gallaccio, G., Dehlinger, A., Dames, C., Leman, J.K.H., van Dijk, R.E., Meisel, A., Schlickeiser, S., Kunkel, D., Hol, E.M., Paul, F., Parr, M.K., Priller, J. and Böttcher, C.
Nature Communications 13 (1): 7210. 23 November 2022

Comprehensive cerebrospinal fluid analysis indicates key roles for B cells in multiple sclerosis.
Fernández-Zapata, C., Otto, C., Gallaccio, G., Chen, Q., Wang, M., Uluvar, B., Teves, M., Samol, C., Buthut, M., Bösl, F.R., Dehlinger, A., Jang, G.H., Böttcher, C., Radbruch, H., Priller, J., Schindler, P., Raposo, C., Shippling, S., Pedotti, R., Kunkel, D., Pietzner, M., Franke, C., Oefner, P.J., Gronwald, W., Prüß, H., Lohmeier, J., Paul, F., Ruprecht, K. and Böttcher, C.
medRxiv : 2025.01.02.24319302. 6 January 2025

Protocol to characterize immune cell subpopulations in cerebrospinal fluid of patients with neuroinflammatory diseases using mass cytometry.
Gallaccio, G., Wang, M., Schlickeiser, S., Kunkel, D., Böttcher, C. and Fernández-Zapata, C.
STAR Protocols 5 (2): 103038. 27 April 2024

Isotopic tracing of glucose metabolites in human monocytes to assess changes in inflammatory conditions.
Giacomello, G., Böttcher, C. and Parr, M.K.
STAR Protocols 3 (4): 101715. 16 December 2022

1,2-(13)C(2)-glucose tracing approach to assess metabolic alterations of human monocytes under neuroinflammatory conditions.
Giacomello, G., Otto, C., Priller, J., Ruprecht, K., Böttcher, C. and Parr, M.K.
Current Issues in Molecular Biology 45 (1): 765-781. 16 January 2023

Diverse modulatory effects of bibenzyls from Dendrobium species on human immune cell responses under inflammatory conditions.
Kongkatitham, V., Dehlinger, A., Chaotham, C., Likhitwitayawuid, K., Böttcher, C. and Sritularak, B.
PLoS ONE 19 (2): e0292366. 1 February 2024

Immunomodulatory effects of new phenanthrene derivatives from Dendrobium crumenatum.
Kongkatitham, V., Dehlinger, A., Wang, M., Poldorn, P., Weidinger, C., Letizia, M., Chaotham, C., Otto, C., Ruprecht, K., Paul, F., Rungrotmongkol, T., Likhitwitayawuid, K., Böttcher, C. and Sritularak, B.
Journal of Natural Products 86 (5): 1294-1306. 26 May 2023

Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M., Wang, Y.H., Kaufmann, U., Gerbeth, L., Sand, A., Brunkhorst, M., Weidner, P., Ziegler, J.F., Böttcher, C., Schlickeiser, S., Fernández, C., Yamashita, M., Stauderman, K., Sun, K., Kunkel, D., Prakriya, M., Sanders, A.D., Siegmund, B., Feske, S. and Weidinger, C.
EMBO Molecular Medicine 14 (9): e15687. 7 September 2022

SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt, L., Braun, J., Fauchere, F., Vanshylla, K., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Jürchott, K., Mangold, M., Maraj, A., Braginets, A., Böttcher, C., Nitsche, A., de la Rosa, K., Ratswohl, C., Sawitzki, B., Holenya, P., Reimer, U., Sander, L.E., Klein, F., Paul, F., Bellmann-Strobl, J., Thiel, A. and Giesecke-Thiel, C.
Journal of Neurology Neurosurgery and Psychiatry 93 (9): 960-971. September 2022

Single-cell variations of circadian clock and immune gene expression in microglia and neurodegeneration.
Ouk, K., Yalcin, M., Rigat, L., Keren-Shaul, H., David, E., Knop, A., Böttcher, C., Kramer, A., Amit, I., Relógio, A. and Priller, J.
bioRxiv : 2024.06.16.599193. 16 June 2024

Immunomodulatory potential of a bibenzyl-dihydrophenanthrene derivative isolated from Calanthe cardioglossa.
Pengdee, C., Dehlinger, A., Chaichompoo, W., Kongkatitham, V., Chaotham, C., Rojsitthisak, P., Böttcher, C. and Sritularak, B.
Journal of Natural Products 88 (2): 537-545. 28 February 2025

Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19.
Radke, J., Meinhardt, J., Aschman, T., Chua, R.L., Farztdinov, V., Lukassen, S., Ten, F.W., Friebel, E., Ishaque, N., Franz, J., Huhle, V.H., Mothes, R., Peters, K., Thomas, C., Schneeberger, S., Schumann, E., Kawelke, L., Jünger, J., Horst, V., Streit, S., von Manitius, R., Körtvélyessy, P., Vielhaber, S., Reinhold, D., Hauser, A.E., Osterloh, A., Enghard, P., Ihlow, J., Elezkurtaj, S., Horst, D., Kurth, F., Müller, M.A., Gassen, N.C., Melchert, J., Jechow, K., Timmermann, B., Fernandez-Zapata, C., Böttcher, C., Stenzel, W., Krüger, E., Landthaler, M., Wyler, E., Corman, V., Stadelmann, C., Ralser, M., Eils, R., Heppner, F.L., Mülleder, M., Conrad, C. and Radbruch, H.
Nature Neuroscience 27 (3): 409-420. March 2024

Inhibitory effect of isopanduratin A on adipogenesis: a study of possible mechanisms.
Rungsa, P., San, H.T., Sritularak, B., Böttcher, C., Prompetchara, E., Chaotham, C. and Likhitwitayawuid, K.
Foods 12 (5): 1014. 27 February 2023

Protocol of a prospective multicenter study on comorbidity impact on multiple sclerosis and antibody-mediated diseases of the central nervous system (COMMIT).
Samadzadeh, S., Adnan, R., Berglova, P., Barzegar, M., Debrabant, B., Roikjaer, S.G., Levy, M., Petzold, A., Palace, J., Flanagan, E.P., Mariotto, S., Skou, S.T., Froelich, A., Lotan, I., Messina, S., Geraldes, R., Asseyer, S., Stiebel-Kalish, H., Oertel, F.C., Shaygannejad, V., Sahraian, M.A., Kim, H.J., Bennett, J.L., Böttcher, C., Zimmermann, H.G., Weinshenker, B.G., Paul, F. and Asgari, N.
Frontiers in Immunology 15 : 1380025. 2 July 2024

Multiomic spatial landscape of innate immune cells at human central nervous system borders.
Sankowski, R., Süß, P., Benkendorff, A., Böttcher, C., Fernandez-Zapata, C., Chhatbar, C., Cahueau, J., Monaco, G., Gasull, A.D., Khavaran, A., Grauvogel, J., Scheiwe, C., Shah, M.J., Heiland, D.H., Schnell, O., Markfeld-Erol, F., Kunze, M., Zeiser, R., Priller, J. and Prinz, M.
Nature Medicine 30 (1): 186-198. January 2024

Berlin Registry of Neuroimmunological entities (BERLimmun): protocol of a prospective observational study.
Sperber, P.S., Brandt, A.U., Zimmermann, H.G., Bahr, L.S., Chien, C., Rekers, S., Mähler, A., Böttcher, C., Asseyer, S., Duchow, A.S., Bellmann-Strobl, J., Ruprecht, K., Paul, F. and Schmitz-Hübsch, T.
BMC Neurology 22 (1): 479. 14 December 2022

New phenanthrenequinones from Cymbidium ensifolium roots and their anti-inflammatory activity on lipopolysaccharide-activated BV2 microglial cells.
Thant, M.T., Hasriadi, H., Poldorn, P., Jungsuttiwong, S., Rojsitthisak, P., Böttcher, C., Towiwat, P. and Sritularak, B.
RSC Advances 14 (39): 28390-28400. 5 September 2024

New phenolic glycosides from Coelogyne fuscescens Lindl. var. brunnea and their cytotoxicity against human breast cancer cells.
Thant, M.T., Bhummaphan, N., Wuttiin, J., Puttipanyalears, C., Chaichompoo, W., Rojsitthisak, P., Punpreuk, Y., Böttcher, C., Likhitwitayawuid, K. and Sritularak, B.
ACS Omega 9 (7): 7679-7691. 20 February 2024

Associations of myeloid cells with cellular and humoral responses following vaccinations in patients with neuroimmunological diseases.
Wang, M., Dehlinger, A., Fernández Zapata, C., Golan, M., Gallaccio, G., Sander, L.E., Schlickeiser, S., Kunkel, D., Schmitz-Hübsch, T., Sawitzki, B., Karni, A., Braun, J., Loyal, L., Thiel, A., Bellmann-Strobl, J., Paul, F., Meyer-Arndt, L. and Boettcher, C.
Nature Communications 14 (1): 7728. 25 November 2023

Cardoso, Cristina

A fluorescent two-hybrid (F2H) assay for direct visualization of protein interactions in living cells.
Zolghadr, K., Mortusewicz, O., Rothbauer, U., Kleinhans, R., Goehler, H., Wanker, E.E., Cardoso, M.C. and Leonhardt, H.
Molecular and Cellular Proteomics 7 (11): 2279-2287. 1 November 2008

Chekulaeva, Marina (BIMSB)

Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A., Gündüz, I.B., Franke, V., Uyar, B. and Akalin, A.
Cancers 14 (22): 5604. 15 November 2022

Transcriptome analysis reveals high tumor heterogeneity with respect to re-activation of stemness and proliferation programs.
Baranovsky, A., Ivanov, T., Granovskaya, M., Papatsenko, D. and Pervouchine, D.D.
PLoS ONE 17 (5): e0268626. 19 May 2022

The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression.
Bujanic, L., Shevchuk, O., von Kügelgen, N., Kalinina, A., Ludwik, K., Koppstein, D., Zerna, N., Sickmann, A. and Chekulaeva, M.
RNA 28 (5): 766-779. May 2022

Mechanistic insights into the basis of widespread RNA localization.
Chekulaeva, M.
Nature Cell Biology 26 (7): 1037-1046. July 2024

First demonstration of miRNA-dependent mRNA decay.
Chekulaeva, M.
Nature Reviews Molecular Cell Biology 24 (3): 164. March 2023

Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63 (6): 918-925. 15 September 2016

Roles of long noncoding RNAs and circular RNAs in translation.
Chekulaeva, M. and Rajewsky, N.
Cold Spring Harbor Perspectives in Biology 11 (6): a032680. 3 June 2019

Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C., Rom, A., Franke, V., Imami, K., Arrey, G., Terne, M., Woehler, A., Akalin, A., Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47 (5): 2560-2573. 18 March 2019

Concurrent profiling of localized transcriptome and RNA dynamics in neurons by spatial SLAMseq.
Dantsuji, S. and Chekulaeva, M.
Methods in Molecular Biology 2863 : 297-317. 2025

Identifying tumor cells at the single-cell level using machine learning.
Dohmen, J., Baranovskii, A., Ronen, J., Uyar, B., Franke, V. and Akalin, A.
Genome Biology 23 (1): 123. 30 May 2022

MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari, F., Dahlmann, M., Sporbert, A., Ciolli Mattioli, C., Mari, T., Scholz, F., Timm, L., Twamley, S., Migotti, R., Walther, W., Dittmar, G., Rehm, A. and Stein, U.
Cellular and Molecular Life Sciences 78 (7): 3525-3542. April 2021

mRNA stability and m(6)A are major determinants of subcellular mRNA localization in neurons.
Loedige, I., Baranovskii, A., Mendonsa, S., Dantsuji, S., Popitsch, N., Breimann, L., Zerna, N., Cherepanov, V., Milek, M., Ameres, S. and Chekulaeva, M.
Molecular Cell 83 (15): 2709-2725. 3 August 2023

Genome-wide analysis of RNA and protein localization and local translation in mESC-derived neurons.
Ludwik, K.A., von Kuegelgen, N. and Chekulaeva, M.
Methods 162-163 : 31-41. June 2019

Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution.
Mauri, M., Kirchner, M., Aharoni, R., Ciolli Mattioli, C., van den Bruck, D., Gutkovitch, N., Modepalli, V., Selbach, M., Moran, Y. and Chekulaeva, M.
Nucleic Acids Research 45 (2): 938-950. 25 January 2017

Charcot-Marie-Tooth mutation in glycyl-tRNA synthetase stalls ribosomes in a pre-accommodation state and activates integrated stress response.
Mendonsa, S., von Kuegelgen, N., Bujanic, L. and Chekulaeva, M.
Nucleic Acids Research 49 (17): 10007-10017. 27 September 2021

Massively parallel identification of mRNA localization elements in primary cortical neurons.
Mendonsa, S., von Kügelgen, N., Dantsuji, S., Ron, M., Breimann, L., Baranovskii, A., Lödige, I., Kirchner, M., Fischer, M., Zerna, N., Bujanic, L., Mertins, P., Ulitsky, I. and Chekulaeva, M.
Nature Neuroscience 26 (3): 394-405. March 2023

Translation of circRNAs.
Pamudurti, N.R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., Shenzis, S., Samson, M., Dittmar, G., Landthaler, M., Chekulaeva, M., Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

Viruses and endogenous retroviruses as roots for neuroinflammation and neurodegenerative diseases.
Römer, C.
Frontiers in Neuroscience 15 : 648629. 12 March 2021

A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.
Witte, F., Ruiz-Orera, J., Ciolli Mattioli, C., Blachut, S., Adami, E., Schulz, J.F., Schneider-Lunitz, V., Hummel, O., Patone, G., Mücke, M.B., Šilhavý, Jan, Heinig, M., Bottolo, L., Sanchis, D., Vingron, M., Chekulaeva, M., Pravenec, M., Hubner, N. and van Heesch, S.
Genome Biology 22 (1): 191. 28 June 2021

RNA localization is a key determinant of neurite-enriched proteome.
Zappulo, A., van den Bruck, D., Ciolli Mattioli, C., Franke, V., Imami, K., McShane, E., Moreno-Estelles, M., Calviello, L., Filipchyk, A., Peguero-Sanchez, E., Müller, T., Woehler, A., Birchmeier, C., Merino, E., Rajewsky, N., Ohler, U., Mazzoni, E.O., Selbach, M., Akalin, A. and Chekulaeva, M.
Nature Communications 8 (1): 583. 19 September 2017

Novel targets, treatments, and advanced models for intracerebral haemorrhage.
Zille, M., Farr, T.D., Keep, R.F., Römer, C., Xi, G. and Boltze, J.
EBioMedicine 76 : 103880. 12 February 2022

Neuromuscular dysfunction in patient-derived FUS(R244RR)-ALS iPSC model via axonal downregulation of neuromuscular junction proteins.
von Kuegelgen, N., Ludwik, K., Mendonsa, S., Roemer, C., Becher, E., Breimann, L., Strauch, M., Mari, T., Mongellaz, S., Zuckerman, B., Grexa, N., Oliveras-Martinez, A., Woehler, A., Selbach, M., La Bella, V., Ulitsky, I. and Chekulaeva, M.
bioRxiv : 2024.08.17.607965. 17 August 2024

Conservation of a core neurite transcriptome across neuronal types and species.
von Kügelgen, N. and Chekulaeva, M.
Wiley Interdisciplinary Reviews: RNA 11 (4): e1590. July 2020

Chen, Wei (BIMSB/BIH)

The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B., Wang, X., Eichelbaum, K., Sadewasser, A., Husic, I., Paki, K., Budt, M., Hergeselle, M., Vetter, B., Hou, J., Chen, W., Wiebusch, L., Meyer, I.M., Wolff, T. and Selbach, M.
Nature Communications 10 (1): 5518. 4 December 2019

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Buonocore, F., Kuehnen, P., Suntharalingham, J.P., Del Valle, I., Digweed, M., Stachelscheid, H., Khajavi, N., Didi, M., Brady, A.F., Blankenstein, O., Procter, A.M., Dimitri, P., Wales, J.K.H., Ghirri, P., Knoebl, D., Strahm, B., Erlacher, M., Wlodarski, M.W., Chen, W., Kokai, G.K., Anderson, G., Morrogh, D., Moulding, D.A., McKee, S. A., Niemeyer, C.M., Grueters, A. and Achermann, J.C.
Journal of Clinical Investigation 127 (5): 1700-1713. 1 May 2017

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.
Hu, H., Haas, S.A., Chelly, J., Van Esch, H., Raynaud, M., de Brouwer, A.P.M., Weinert, S., Froyen, G., Frints, S.G.M., Laumonnier, F., Zemojtel, T., Love, M.I., Richard, H., Emde, A.K., Bienek, M., Jensen, C., Hambrock, M., Fischer, U., Langnick, C., Feldkamp, M., Wissink-Lindhout, W., Lebrun, N., Castelnau, L., Rucci, J., Montjean, R., Dorseuil, O., Billuart, P., Stuhlmann, T., Shaw, M., Corbett, M.A., Gardner, A., Willis-Owen, S., Tan, C., Friend, K.L., Belet, S., van Roozendaal, K.E.P., Jimenez-Pocquet, M., Moizard, M.P., Ronce, N., Sun, R., O'Keeffe, S., Chenna, R., van Bömmel, A., Goeke, J., Hackett, A., Field, M., Christie, L., Boyle, J., Haan, E., Nelson, J., Turner, G., Baynam, G., Gillessen-Kaesbach, G., Mueller, U., Steinberger, D., Budny, B., Badura-Stronka, M., Latos-Bieleńska, A., Ousager, L.B., Wieacker, P., Rodríguez Criado, G., Bondeson, M.L., Annerén, G., Dufke, A., Cohen, M., Van Maldergem, L., Vincent-Delorme, C., Echenne, B., Simon-Bouy, B., Kleefstra, T., Willemsen, M., Fryns, J.P., Devriendt, K., Ullmann, R., Vingron, M., Wrogemann, K., Wienker, T.F., Tzschach, A., van Bokhoven, H., Gecz, J., Jentsch, T.J., Chen, W., Ropers, H.H. and Kalscheuer, V.M.
Molecular Psychiatry 21 (1): 133-148. January 2016

Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.
Jia, S., Ivanov, A., Blasevic, D., Müller, T., Purfürst, B., Sun, W., Chen, W., Poy, M.N., Rajewsky, N. and Birchmeier, C.
EMBO Journal 34 (10): 1417-1433. 12 May 2015

Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A., Sengul, T.G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M.H., Ofenbauer, A., Gesell-Salazar, M., Balogh, A., Kempa, S., Tursun, B., Robbins, C.T., Völker, U., Chen, W., Nelson, L. and Gotthardt, M.
Scientific Reports 9 (1): 19976. 27 December 2019

Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
Szulzewsky, F., Pelz, A., Feng, X., Synowitz, M., Markovic, D., Langmann, T., Holtman, I.R., Wang, X., Eggen, B.J.L., Boddeke, H.W.G.M., Hambardzumyan, D., Wolf, S.A. and Kettenmann, H.
PLoS ONE 10 (2): e0116644. 6 February 2015

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J., Xie, G., Singh, M., Ghanbarian, A.T., Raskó, T., Szvetnik, A., Cai, H., Besser, D., Prigione, A., Fuchs, N.V., Schumann, G.G., Chen, W., Lorincz, M.C., Ivics, Z., Hurst, L.D. and Izsvák, Z.
Nature 516 (7531): 405-409. 18 December 2014

Whole genome sequencing and methylome analysis of the wild guinea pig.
Weyrich, A., Schuellermann, T., Heeger, F., Jeschek, M., Mazzoni, C.J., Chen, W., Schumann, K. and Fickel, J.
BMC Genomics 15 (1): 1036. 28 November 2014

Identification of a new genomic hot spot of evolutionary diversification of protein function.
Winkelmann, A., You, X., Gruenewald, N., Haeussler, U., Krestel, H., Haas, C.A., Schwarz, G., Chen, W. and Meier, J.C.
PLoS ONE 10 (5): e0125413. 8 May 2015

Discovering the mechanisms underlying serotonin (5-HT)2A and 5-HT2C receptor regulation following nicotine withdrawal in rats.
Zaniewska, M., Alenina, N., Wydra, K., Fröhler, S., Kuśmider, M., McCreary, A.C., Chen, W., Bader, M. and Filip, M.
Journal of Neurochemistry 134 (4): 704-716. August 2015

Christ, Annabel

LRP2 acts as SHH clearance receptor to protect the retinal margin from mitogenic stimuli.
Christ, A., Christa, A., Klippert, J., Eule, J.C., Bachmann, S., Wallace, V.A., Hammes, A. and Willnow, T.E.
Developmental Cell 35 (1): 36-48. 12 October 2015

Colla, Michael (ECRC)

Differences in maintenance of response upon discontinuation across medication treatments in attention-deficit/hyperactivity disorder.
Buitelaar, J., Asherson, P., Soutullo, C., Colla, M., Adams, D.H., Tanaka, Y., Haynes, V.S., Escobar, R. and Upadhyaya, H.
European Neuropsychopharmacology 25 (10): 1611–1621. October 2015

German validation of the conners adult ADHD rating scale-self-report: confirmation of factor structure in a large sample of participants with ADHD.
Christiansen, H., Hirsch, O., Philipsen, A., Oades, R.D., Matthies, S., Hebebrand, J., Ueckermann, J., Abdel-Hamid, M., Kraemer, M., Wiltfang, J., Graf, E., Colla, M., Sobanski, E., Alm, B., Roesler, M., Jacob, C., Jans, T., Huss, M., Schimmelmann, B.G. and Kis, B.
Journal of Attention Disorders 17 (8): 690-698. November 2013

Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders.
Dukart, J., Regen, F., Kherif, F., Colla, M., Bajbouj, M., Heuser, I., Frackowiak, R.S. and Draganski, B.
Proceedings of the National Academy of Sciences of the United States of America 111 (3): 1156-1161. 21 January 2014

Child impact on family functioning: a multivariate analysis in multiplex families with children and mothers both affected by attention-deficit/hyperactivity disorder (ADHD).
Fleck, K., Jacob, C., Philipsen, A., Matthies, S., Graf, E., Hennighausen, K., Haack-Dees, B., Weyers, P., Warnke, A., Roesler, M., Retz, W., von Gontard, A., Haenig, S., Freitag, C., Sobanski, E., Schumacher-Stien, M., Poustka, L., Bliznak, L., Becker, K., Holtmann, M., Colla, M., Gentschow, L., Kappel, V., Jaite, C. and Jans, T.
Attention Deficit and Hyperactivity Disorders 7 (3): 211-223. September 2015

Characterization, treatment patterns, and patient-related outcomes of patients with Fragile X syndrome in Germany: final results of the observational EXPLAIN-FXS study.
Haessler, F., Gaese, F., Huss, M., Kretschmar, C., Brinkman, M., Peters, H., Elstner, S., Colla, M. and Pittrow, D.
BMC Psychiatry 16 (1): 318. 10 September 2016

Retinoic acid as target for local pharmacokinetic interaction with modafinil in neural cells.
Hellmann-Regen, J., Gertz, K., Uhlemann, R., Colla, M., Endres, M. and Kronenberg, G.
European Archives of Psychiatry and Clinical Neuroscience 262 (8): 697-704. December 2012

Pilot study of psychiatric and social aspects of children and adolescents with fragile X syndrome [Pilotstudie zu psychiatrischen und sozialen Aspekten bei Kindern und Jugendlichen mit Fragilem-X-Syndrom (FRX)].
Häßler, F., Gaese, F., Colla, M., Huss, M., Kretschmar, C., Brinkman, M., Peters, H., Elstner, S., Weirich, S. and Pittrow, D.
Zeitschrift fuer Kinder- und Jugendpsychiatrie und Psychotherapie 45 (2): 141-147. March 2017

Does intensive multimodal treatment for maternal ADHD improve the efficacy of parent training for children with ADHD? A randomized controlled multicenter trial.
Jans, T., Jacob, C., Warnke, A., Zwanzger, U., Gross-Lesch, S., Matthies, S., Borel, P., Hennighausen, K., Haack-Dees, B., Roesler, M., Retz, W., von Gontard, A., Haenig, S., Sobanski, E., Alm, B., Poustka, L., Hohmann, S., Colla, M., Gentschow, L., Jaite, C., Kappel, V., Becker, K., Holtmann, M., Freitag, C., Graf, E., Ihorst, G. and Philipsen, A.
Journal of Child Psychology and Psychiatry 56 (12): 1298-1313. December 2015

Effect of specific psychotherapy for chronic depression on neural Responses to emotional faces.
Klein, J.P., Becker, B., Hurlemann, R., Scheibe, C., Colla, M. and Heuser, I.
Journal of Affective Disorders 166 : 93-97. September 2014

A randomized controlled multicenter trial on the multimodal treatment of adult attention-deficit hyperactivity disorder: enrollment and characteristics of the study sample.
Philipsen, A., Graf, E., Jans, T., Matthies, S., Borel, P., Colla, M., Gentschow, L., Langner, D., Jacob, C., Gross-Lesch, S., Sobanski, E., Alm, B., Schumacher-Stien, M., Roesler, M., Retz, W., Retz-Junginger, P., Kis, B., Abdel-Hamid, M., Heinrich, V., Huss, M., Kornmann, C., Buerger, A., van Elst, L.T. and Berger, M.
Attention Deficit and Hyperactivity Disorders 6 (1): 35-47. March 2014

Effects of group psychotherapy, individual counseling, methylphenidate, and placebo in the treatment of adult attention-deficit/hyperactivity disorder: a randomized clinical trial.
Philipsen, A., Jans, T., Graf, E., Matthies, S., Borel, P., Colla, M., Gentschow, L., Langner, D., Jacob, C., Gross-Lesch, S., Sobanski, E., Alm, B., Schumacher-Stien, M., Roesler, M., Retz, W., Retz-Junginger, P., Kis, B., Abdel-Hamid, M., Heinrich, V., Huss, M., Kornmann, C., Buerger, A., Perlov, E., Ihorst, G., Schlander, M., Berger, M. and Tebartz van Elst, L.
JAMA Psychiatry 72 (12): 1199-1210. December 2015

Psychiatrische und soziale Aspekte bei Patienten mit fragilem X-Syndrom (FRX) [Psychiatric and social aspects of patients with fragile X Syndrome].
Pittrow, D., Gaese, F., Colla, M., Huss, M., Kretschmar, C., Brinkman, M., Peters, H., Elstner, S., Weirich, S. and Haessler, F.
Psychiatrische Praxis 43 (3): 160-164. April 2016

Leptin plasma concentrations increase during antidepressant treatment with amitriptyline and mirtazapine, but not paroxetine and venlafaxine: leptin resistance mediated by antihistaminergic activity?
Schilling, C., Gilles, M., Blum, W.F., Daseking, E., Colla, M., Weber-Hamann, B., Lederbogen, F., Krumm, B., Heuser, I., Wudy, S.A., Kopf, D. and Deuschle, M.
Journal of Clinical Psychopharmacology 33 (1): 99-103. February 2013

Damaschun, Gregor

Studien zur Kinetik der Fehlfaltung und Aggregation von Proteinen.
Modler, A.J.
UNSPECIFIED thesis, UNSPECIFIED. 23 October 2003

The database BIOSCAT: a tool for structure research by scattering and hydrodynamic methods.
Mueller, J.J., Pankow, H., Poppe, B. and Damaschun, G.
Journal of Applied Crystallography 25 (Pt 6): 803-806. 1 December 1992

The inertia-equivalent ellipsoid: a link between atomic structure and low-resolution models of small globular proteins determined by small-angle x-ray scattering.
Mueller, J.J. and Schrauber, H.
Journal of Applied Crystallography 25 (Pt 2): 181-191. 1 April 1992

Daumke, Oliver

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A., Roske, Y., Barth, C., Lleras Forero, L., Bravo-Rodriguez, K., Redel, Al., Kostova, S., McShane, E., Opitz, R., Faelber, K., Rau, K., Mielke, T., Daumke, O., Selbach, M., Sanchez-Garcia, E., Rocks, O., Panáková, D., Heinemann, U. and Wanker, E.E.
Nature Communications 7 : 13047. 20 October 2016

A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand, J., Smith, E.S.J., Schwefel, D., Lapatsina, L., Poole, K., Omerbasic, D., Kozlenkov, A., Behlke, J., Lewin, G.R. and Daumke, O.
EMBO Journal 31 (17): 3635-3646. 29 August 2012

SPFH protein cage - one ring to rule them all.
Daumke, O. and Lewin, G.R.
Cell Research 32 (2): 117-118. February 2022

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L., Czajkowski, M.T., Barth, C., Müller, P.M., McShane, E., Grunwald, S., Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G., Selbach, M., Hammes, A., Daumke, O., Klussmann, E., Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy.
Escobar, H., Di Francescantonio, S., Smirnova, J., Graf, R., Müthel, S., Marg, A., Zhogov, A., Krishna, S., Metzler, E., Petkova, M., Daumke, O., Kühn, R. and Spuler, S.
Nature Communications 16 (1): 120. 2 January 2025

Molecular architecture of synaptic vesicles.
Kravčenko, U., Ruwolt, M., Kroll, J., Yushkevich, A., Zenkner, M., Ruta, J., Lotfy, R., Wanker, E.E., Rosenmund, C., Liu, F. and Kudryashev, M.
Proceedings of the National Academy of Sciences of the United States of America 121 (49): e2407375121. 3 December 2024

Stomatin-domain proteins.
Lapatsina, L., Brand, J., Poole, K., Daumke, O. and Lewin, G.R.
European Journal of Cell Biology 91 (4): 240-245. April 2012

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C., Lahmann, I., Kunz, S., Jonas, W., Melo, A.A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Blüher, M., Olschowski, H., Kompa, J., Brügger, B., Müller, D.N., Haucke, V., Schürmann, A., Birchmeier, C. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 117 (13): 7471-7481. 31 March 2020

eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization.
Matthaeus, C., Lian, X., Kunz, S., Lehmann, M., Zhong, C., Bernert, C., Lahmann, I., Müller, D.N., Gollasch, M. and Daumke, O.
PLoS ONE 14 (10): e0223620. 10 October 2019

Sociality shapes mitochondrial adaptations supporting hypoxia tolerance.
Rossi, A., Ruwolt, M., Kakouri, P., Kosten, T., Kunz, S., Puchkov, D., Reznick, J., Purfürst, B., Omerbašić, D., Méndez Aranda, D., Carai, G., Mastrobuoni, G., Hart, D.W., Carraro, M., Tommasin, L., Bennett, N.C., Bégay, V., Faelber, K., Daumke, O., Bernardi, P., Park, T.J., Kempa, S., Liu, F. and Lewin, G.R.
bioRxiv : 2024.09.30.615914. 2 October 2024

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T., Meyer, K., Roske, Y., Uyar, B., Akalin, A., Imami, K., Ishihama, Y., Daumke, O. and Selbach, M.
Nature Communications 15 (1): 3146. 11 April 2024

Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C., Hegde, B.G., Morén, B., Behrmann, E., Mielke, T., Moenke, G., Spahn, C.M., Lundmark, R., Daumke, O. and Langen, R.
Structure 22 (3): 409-420. 4 March 2014

The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells.
Wilhelmi, Ilka, Grunwald, S., Gimber, N., Popp, O., Dittmar, G., Arumughan, A., Wanker, E.E., Laeger, T., Schmoranzer, J., Daumke, O. and Schümann, A.
Molecular Metabolism 45 : 101151. March 2021

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y., Du Jiang, P., Chao, B.N., Cagdas, D., Kubo, S., Balasubramaniyam, A., Zhang, Y., Shadur, B., NaserEddin, A., Folio, L.R., Schwarz, B., Bohrnsen, E., Zheng, L., Lynberg, M., Gottlieb, S., Leney-Greene, M.A., Park, A.Y., Tezcan, I., Akdogan, A., Gocmen, R., Onder, S., Rosenberg, A., Soilleux, E.J., Johnson, E., Jackson, P.K., Demeter, J., Chauvin, S.D., Paul, F., Selbach, M., Bulut, H., Clatworthy, M.R., Tuong, Z.K., Zhang, H., Stewart, B.J., Bosio, C.M., Stepensky, P., Clare, S., Ganesan, S., Pascall, J.C., Daumke, O., Butcher, G.W., McMichael, A.J., Simon, A.K. and Lenardo, M.J.
Journal of Experimental Medicine 219 (6): e20201405. 6 June 2022

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V., McShane, E., Schulz-Beiss, K.W., Patone, G., Schleussner, N., Kolesnichenko, M., Hübner, N., Daumke, O., Selbach, M., Akalin, A., Mathas, S. and Scheidereit, C.
Blood 133 (13): 1489-1494. 28 March 2019

De la Rosa, Kathrin

Discriminating promiscuous from target-specific autoantibodies in COVID-19.
Lebedin, M., Vazquez Garcia, C., Spatt, L., Ratswohl, C., Thibeault, C., Ostendorf, L., Alexander, T., Paul, F., Sander, L.E., Kurth, F. and de la Rosa, K.
European Journal of Immunology 53 (5): e2250210. May 2023

SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt, L., Braun, J., Fauchere, F., Vanshylla, K., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Jürchott, K., Mangold, M., Maraj, A., Braginets, A., Böttcher, C., Nitsche, A., de la Rosa, K., Ratswohl, C., Sawitzki, B., Holenya, P., Reimer, U., Sander, L.E., Klein, F., Paul, F., Bellmann-Strobl, J., Thiel, A. and Giesecke-Thiel, C.
Journal of Neurology Neurosurgery and Psychiatry 93 (9): 960-971. September 2022

Deubzer, Hedwig (ECRC)

Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival.
Thole, T.M., Lodrini, M., Fabian, J., Wuenschel, J., Pfeil, S., Hielscher, T., Kopp-Schneider, A., Heinicke, U., Fulda, S., Witt, O., Eggert, A., Fischer, M. and Deubzer, H.E.
Cell Death & Disease 8 (3): e2635. 2 March 2017

Di Virgilio, Michela

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V., Berruezo-Llacuna, M., Altwasser, R., Winkler, W., Sundaravinayagam, D., Balasubramanian, S., Caganova, M., Graf, R., Rahjouei, A., Henke, M.T., Driesner, M., Keller, L., Prigione, A., Janz, M., Akalin, A. and Di Virgilio, M.
Journal of Experimental Medicine 217 (10): e20200137. 5 October 2020

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H., Pusch, F., Bei, Y., von Stebut, J., Ibáñez, G., Guillan, K., Imami, K., Gürgen, D., Rolff, J., Helmsauer, K., Meyer-Liesener, S., Timme, N., Bardinet, V., Chamorro González, R., MacArthur, I.C., Chen, C.Y., Schulz, J., Wengner, A.M., Furth, C., Lala, B., Eggert, A., Seifert, G., Hundsoerfer, P., Kirchner, M., Mertins, P., Selbach, M., Lissat, A., Dubois, F., Horst, D., Schulte, J.H., Spuler, S., You, D., Dela Cruz, F., Kung, A.L., Haase, K., Di Virgilio, M., Scheer, M., Ortiz, M.V. and Henssen, A.G.
Nature Communications 13 (1): 4297. 25 July 2022

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G., Rybak-Wolf, A., Lisowski, P., Pentimalli, T.M., Jüttner, R., Glažar, P., Uppal, K., Bottani, E., Brunetti, D., Secker, C., Zink, A., Meierhofer, D., Henke, M.T., Dey, M., Ciptasari, U., Mlody, B., Hahn, T., Berruezo-Llacuna, M., Karaiskos, N., Di Virgilio, M., Mayr, J.A., Wortmann, S.B., Priller, J., Gotthardt, M., Jones, D.P., Mayatepek, E., Stenzel, W., Diecke, S., Kühn, R., Wanker, E.E., Rajewsky, N., Schuelke, M. and Prigione, A.
Nature Communications 12 (1): 1929. 26 March 2021

Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J., Sundaravinayagam, D., Blume, A., Marg, A., Grunwald, S., Metzler, E., Escobar, H., Müthel, S., Wang, H., Wollersheim, T., Weber-Carstens, S., Akalin, A., Di Virgilio, M., Tursun, B. and Spuler, S.
International Journal of Molecular Sciences 24 (3): 2772. 1 February 2023

Diecke, Sebastian (MDC/BIH)

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G., Rybak-Wolf, A., Lisowski, P., Pentimalli, T.M., Jüttner, R., Glažar, P., Uppal, K., Bottani, E., Brunetti, D., Secker, C., Zink, A., Meierhofer, D., Henke, M.T., Dey, M., Ciptasari, U., Mlody, B., Hahn, T., Berruezo-Llacuna, M., Karaiskos, N., Di Virgilio, M., Mayr, J.A., Wortmann, S.B., Priller, J., Gotthardt, M., Jones, D.P., Mayatepek, E., Stenzel, W., Diecke, S., Kühn, R., Wanker, E.E., Rajewsky, N., Schuelke, M. and Prigione, A.
Nature Communications 12 (1): 1929. 26 March 2021

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J., Muinjonov, B., Rosiewicz, K.S., Diecke, S., Biese, C., Schiweck, J., Chien, C., Zocholl, D., Conrad, T., Paul, F., Alisch, M. and Siffrin, V.
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E., Ofenbauer, A., Bulut, S.I., Uyar, B., Baytek, G., Sommermeier, A., Seelk, S., He, M., Hirsekorn, A., Vucicevic, D., Akalin, A., Diecke, S., Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia.
Kuhrt, L.D., Motta, E., Elmadany, N., Weidling, H., Fritsche-Guenther, R., Efe, I.E., Cobb, O., Chatterjee, J., Boggs, L.G., Schnauß, M., Diecke, S., Semtner, M., Anastasaki, C., Gutmann, D.H. and Kettenmann, H.
Disease Models & Mechanisms 16 (12): dmm049861. December 2023

Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure.
Lisowski, P., Lickfett, S., Rybak-Wolf, A., Menacho, C., Le, S., Pentimalli, T.M., Notopoulou, S., Dykstra, W., Oehler, D., López-Calcerrada, S., Mlody, B., Otto, M., Wu, H., Richter, Y., Roth, P., Anand, R., Kulka, L.A.M., Meierhofer, D., Glazar, P., Legnini, I., Telugu, N.S., Hahn, T., Neuendorf, N., Miller, D.C., Böddrich, A., Polzin, A., Mayatepek, E., Diecke, S., Olzscha, H., Kirstein, J., Ugalde, C., Petrakis, S., Cambridge, S., Rajewsky, N., Kühn, R., Wanker, E.E., Priller, J., Metzger, J.J. and Prigione, A.
Nature Communications 15 (1): 7027. 22 August 2024

Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.
Lorenz, C., Zink, A., Henke, M.T., Staege, S., Mlody, B., Bünning, M., Wanker, E., Diecke, S., Schuelke, M. and Prigione, A.
Stem Cell Research 61 : 102742. May 2022

Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E., Escobar, H., Sunaga-Franze, D.Y., Sauer, S., Diecke, S. and Spuler, S.
Biomedicines 10 (5): 1204. 23 May 2022

Generation of two human induced Pluripotent Stem Cell lines derived from myoblasts (MDCi014-A) and from peripheral blood mononuclear cells (MDCi014-B) from the same donor.
Metzler, E., Telugu, N., Diecke, S., Spuler, S. and Escobar, H.
Stem Cell Research 48 : 101998. October 2020

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K., Kirchner, M., Uyar, B., Cheng, J.Y., Russo, G., Hernandez-Miranda, L.R., Szymborska, A., Zauber, H., Rudolph, I.M., Willnow, T.E., Akalin, A., Haucke, V., Gerhardt, H., Birchmeier, C., Kühn, R., Krauss, M., Diecke, S., Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence.
Miller, D.C., Lisowski, P., Genehr, C., Wanker, E.E., Priller, J., Prigione, A. and Diecke, S.
Stem Cell Research 68 : 103056. April 2023

Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C., Lisowski, P., Lickfett, S., Mlody, B., Bünning, M., Genehr, C., Ulrich, C., Wanker, E.E., Diecke, S., Priller, J. and Prigione, A.
Stem Cell Research 65 : 102976. December 2022

Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.
Rydzanicz, M., Wachowska, M., Cook, E.C., Lisowski, P., Kuźniewska, B., Szymańska, K., Diecke, S., Prigione, A., Szczałuba, K., Szybińska, A., Koppolu, A., Murcia Pienkowski, V., Kosińska, J., Wiweger, M., Kostrzewa, G., Brzozowska, M., Domańska-Pakieła, D., Jurkiewicz, E., Stawiński, P., Gromadka, A., Zielenkiewicz, P., Demkow, U., Dziembowska, M., Kuźnicki, J., Creamer, T.P. and Płoski, R.
European Journal of Human Genetics 27 (1): 61-69. January 2019

Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A., Lahmann, I., Nguyen, L.V.N., Rost, B.R., García-Pérez, A., Lelievre, N., Merritt-Garza, M.E., Phan, H.C, Bassell, G.J., Rossoll, W., Diecke, S., Kunz, S., Schmitz, D. and Gouti, M.
Nature Communications 14 (1): 8043. 19 December 2023

Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay.
Zink, A., Conrad, J., Telugu, N.S., Diecke, S., Heinz, A., Wanker, E., Priller, J. and Prigione, A.
Frontiers in Cell and Developmental Biology 8 : 590540. 5 November 2020

Dietz, Rainer

Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.
Katchanov, J., Harms, C., Gertz, K., Hauck, L., Waeber, C., Hirt, L., Priller, J., von Harsdorf, R., Brueck, W., Hoertnagl, H., Dirnagl, U., Bhide, P.G. and Endres, M.
Journal of Neuroscience 21 (14): 5045-5053. 15 July 2001

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S., Hübner, N., Chien, K.R., Birchmeier, C. and Garratt, A.N.
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Dittmar, Gunnar

S-palmitoylation is required for the control of growth cone morphology of DRG neurons by CNP-induced cGMP signaling.
Dumoulin, A., Dagane, A., Dittmar, G. and Rathjen, F.G.
Frontiers in Molecular Neuroscience 11 : 345. 24 September 2018

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L., Czajkowski, M.T., Barth, C., Müller, P.M., McShane, E., Grunwald, S., Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G., Selbach, M., Hammes, A., Daumke, O., Klussmann, E., Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
Scientific Reports 10 : 2158. 7 February 2020

An eicosanoid protects from statin-induced myopathic changes in primary human cells.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
bioRxiv : 271932. 26 February 2018

Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F., a Dzaye, O.D., Hahn, A., Yu, Y., Scavetta, R.J., Dittmar, G., Kaczmarek, A.K., Dunning, K.R., Ricciardelli, C., Rinnenthal, J.L., Heppner, F.L., Lehnardt, S., Synowitz, M., Wolf, S.A. and Kettenmann, H.
Neuro-Oncology 17 (2): 200-210. February 2015

Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy.
Langhans, C., Weber-Carstens, S., Schmidt, F., Hamati, J., Kny, M., Zhu, X., Wollersheim, T., Koch, S., Krebs, M., Schulz, H., Lodka, D., Saar, K., Labeit, S., Spies, C., Hubner, N., Spranger, J., Spuler, S., Boschmann, M., Dittmar, G., Butler-Browne, G., Mouly, V. and Fielitz, J.
PLoS ONE 9 (3): e92048. 20 March 2014

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D., Pahuja, A., Geers-Knörr, C., Scheibe, R., Nowak, M., Hamati, J., Köhncke, C., Purfürst, B., Kanashova, T., Schmidt, S., Glass, D.J., Morano, I., Heuser, A., Kraft, T., Bassel-Duby, R., Olson, E.N., Dittmar, G., Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180. May 2016

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
Nowak, M., Suenkel, B., Porras, P., Migotti, R., Schmidt, F., Kny, M., Zhu, X., Wanker, E.E., Dittmar, G., Fielitz, J. and Sommer, T.
Journal of Cell Science 132 (17): jcs233395. 6 September 2019

Translation of circRNAs.
Pamudurti, N.R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., Shenzis, S., Samson, M., Dittmar, G., Landthaler, M., Chekulaeva, M., Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

GIPC1 regulates MACC1-driven metastasis.
Siegel, F., Schmidt, H., Juneja, M., Smith, J., Herrmann, P., Kobelt, D., Sharma, K., Fichtner, I., Walther, W., Dittmar, G., Volkmer, R., Rathjen, F.G., Schlag, P.M. and Stein, U.
Frontiers in Oncology 13 : 1280977. 8 December 2023

Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1.
Stock, K., Kumar, J., Synowitz, M., Petrosino, S., Imperatore, R., Smith, E.S.J., Wend, P., Purfürst, B., Nuber, U.A., Gurok, U., Matyash, V., Waelzlein, J.H., Chirasani, S.R., Dittmar, G., Cravatt, B.F., Momma, S., Lewin, G.R., Ligresti, A., De Petrocellis, L., Cristino, L., Di Marzo, V., Kettenmann, H. and Glass, R.
Nature Medicine 18 (8): 1232-1238. August 2012

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.
Subkhangulova, A., Malik, A.R., Hermey, G., Popp, O., Dittmar, G., Rathjen, T., Poy, M.N., Stumpf, A., Beed, P.S., Schmitz, D., Breiderhoff, T. and Willnow, T.E.
EMBO Reports 19 (4): e44810. 1 April 2018

The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells.
Wilhelmi, Ilka, Grunwald, S., Gimber, N., Popp, O., Dittmar, G., Arumughan, A., Wanker, E.E., Laeger, T., Schmoranzer, J., Daumke, O. and Schümann, A.
Molecular Metabolism 45 : 101151. March 2021

Doerken, Bernd (MDC/ECRC)

Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation.
Scholz, C., Patton, K.T., Anderson, D.E., Freeman, G.J. and Hafler, D.A.
Journal of Immunology 160 (3): 1532-1538. 1 February 1998

Role of EBAG9 protein in coat protein complex I-dependent glycoprotein maturation and secretion processes in tumor cells.
Wolf, J., Reimer, T.A., Schuck, S., Rueder, C., Gerlach, K., Mueller, E.C., Otto, A., Doerken, B. and Rehm, A.
FASEB Journal 24 (10): 4000-4019. October 2010

Falcke, Martin

Proarrhythmic remodelling of the right ventricle in a porcine model of repaired tetralogy of Fallot.
Benoist, D., Dubes, V., Roubertie, F., Gilbert, S.H., Charron, S., Constantin, M., Elbes, D., Vieillot, D., Quesson, B., Cochet, H., Haissaguerre, M., Rooryck, C., Bordachar, P., Thambo, J.B. and Bernus, O.
Heart 103 (5): 347-354. March 2017

Comparison of diffusion tensor imaging by cardiovascular magnetic resonance and gadolinium enhanced 3D image intensity approaches to investigation of structural anisotropy in explanted rat hearts.
Bernus, O., Radjenovic, A., Trew, M.L., LeGrice, I.J., Sands, G.B., Magee, D.R., Smaill, B.H. and Gilbert, S.H.
Journal of Cardiovascular Magnetic Resonance 17 (1): 31. 29 April 2015

A stochastic model of calcium puffs based on single-channel data.
Cao, P., Donovan, G., Falcke, M. and Sneyd, J.
Biophysical Journal 105 (5): 1133-1142. 3 September 2013

Actin-based propulsion of spatially extended objects.
Enculescu, M. and Falcke, M.
New Journal of Physics 13 : 053040. May 2011

Filament capping and nucleation in actin-based motility.
Faber, M., Enculescu, M. and Falcke, M.
European Physical Journal - Special Topics 191 (1): 147-158. December 2010

Polymerization, bending, tension: What happens at the leading edge of motile cells?
Falcke, M. and Zimmermann, J.
European Physical Journal - Special Topics 223 (7): 1353-1372. June 2014

Membrane waves driven by forces from actin filaments.
Gholami, A., Enculescu, M. and Falcke, M.
New Journal of Physics 14 : 115002. 2 November 2012

Quantification of the transmural dynamics of atrial fibrillation by simultaneous endocardial and epicardial optical mapping in an acute sheep model.
Gutbrod, S.R., Walton, R., Gilbert, S., Meillet, V., Jais, P., Hocini, M., Haissaguerre, M., Dubois, R., Bernus, O. and Efimov, I.
Circulation Arrhythmia and Electrophysiology 8 (2): 456-465. April 2015

Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies.
Hüttemeister, J., Rudolph, F., Radke, M.H., Fink, C., Friedrich, D., Preibisch, S., Falcke, M., Wagner, E., Lehnart, S.E. and Gotthardt, M.
eLife 13 : e95597. 17 December 2024

Histopathology in 3D: from three-dimensional reconstruction to multi-stain and multi-modal analysis.
Magee, D., Song, Y., Gilbert, S., Roberts, N., Wijayathunga, N., Wilcox, R., Bulpitt, A. and Treanor, D.
Journal of Pathology Informatics 6 : 6. 24 February 2015

Hierarchic stochastic modelling applied to intracellular Ca(2+) signals.
Moenke, G., Falcke, M. and Thurley, K.
PLoS ONE 7 (12): e51178. 27 December 2012

Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Mönke, G., Cristiano, E., Finzel, A., Friedrich, D., Herzel, H., Falcke, M. and Loewer, A.
Scientific Reports 7 : 46571. 18 April 2017

Adaptive space and time numerical simulation of reaction-diffusion models for intracellular calcium dynamics.
Nagaiah, C., Ruediger, S., Warnecke, G. and Falcke, M.
Applied Mathematics and Computation 218 (20): 10194-10210. 15 June 2012

Mechanical properties of branched actin filaments.
Razbin, M., Falcke, M., Benetatos, P. and Zippelius, A.
Physical Biology 12 (4): 046007. 4 June 2015

Temperature and nitric oxide control spontaneous calcium transients in astrocytes.
Schipke, C.G., Heidemann, A., Skupin, A., Peters, O., Falcke, M. and Kettenmann, H.
Cell Calcium 43 (3): 285-295. March 2008

Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C., Hegde, B.G., Morén, B., Behrmann, E., Mielke, T., Moenke, G., Spahn, C.M., Lundmark, R., Daumke, O. and Langen, R.
Structure 22 (3): 409-420. 4 March 2014

The role of IP(3)R clustering in Ca(2+) signalinG.
Skupin, A. and Falcke, M.
Genome Informatics 20 : 15-24. June 2008

Calcium signals driven by single channel noise.
Skupin, A., Kettenmann, H. and Falcke, M.
PLoS Computational Biology 6 (8): e1000870. 5 August 2010

How does intracellular Ca2+ oscillate: by chance or by the clock?
Skupin, A., Kettenmann, H., Winkler, U., Wartenberg, M., Sauer, H., Tovey, S.C., Taylor, C.W. and Falcke, M.
Biophysical Journal 94 (6): 2404-2411. 15 March 2008

Calcium signaling: from single channels to pathways.
Skupin, A. and Thurley, K.
Advances in Experimental Medicine and Biology 740 : 531-551. 2012

Fundamental properties of Ca(2+) signals.
Thurley, K., Skupin, A., Thul, R. and Falcke, M.
Biochimica et Biophysica Acta - General Subjects 1820 (8): 1185-1194. August 2012

Timescales of IP(3)-evoked Ca(2+) spikes emerge from Ca(2+) puffs only at the cellular level.
Thurley, K., Smith, I.F., Tovey, S.C., Taylor, C.W., Parker, I. and Falcke, M.
Biophysical Journal 101 (11): 2638-2644. 7 December 2011

Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes.
Thurley, K., Tovey, S.C., Moenke, G., Prince, V.L., Meena, A., Thomas, A.P., Skupin, A., Taylor, C.W. and Falcke, M.
Science Signaling 7 (331): ra59. 24 June 2014

Actin filament elasticity and retrograde flow shape the force-velocity relation of motile cells.
Zimmermann, J., Brunner, C., Enculescu, M., Goegler, M., Ehrlicher, A., Kaes, J. and Falcke, M.
Biophysical Journal 102 (2): 287-295. 18 January 2012

Formation of transient lamellipodia.
Zimmermann, J. and Falcke, M.
PLoS ONE 9 (2): e87638. 5 February 2014

On the existence and strength of stable membrane protrusions.
Zimmermann, J. and Falcke, M.
New Journal of Physics 15 : 015021. January 2013

Fielitz, Jens (ECRC)

HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M., Yu, Y., Liang, L., Vuralli, D., Froehler, S., Kuehnen, P., Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J., Jia, S., Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7 (5): e602. May 2019

Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy.
Langhans, C., Weber-Carstens, S., Schmidt, F., Hamati, J., Kny, M., Zhu, X., Wollersheim, T., Koch, S., Krebs, M., Schulz, H., Lodka, D., Saar, K., Labeit, S., Spies, C., Hubner, N., Spranger, J., Spuler, S., Boschmann, M., Dittmar, G., Butler-Browne, G., Mouly, V. and Fielitz, J.
PLoS ONE 9 (3): e92048. 20 March 2014

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D., Pahuja, A., Geers-Knörr, C., Scheibe, R., Nowak, M., Hamati, J., Köhncke, C., Purfürst, B., Kanashova, T., Schmidt, S., Glass, D.J., Morano, I., Heuser, A., Kraft, T., Bassel-Duby, R., Olson, E.N., Dittmar, G., Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180. May 2016

DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
Nowak, M., Suenkel, B., Porras, P., Migotti, R., Schmidt, F., Kny, M., Zhu, X., Wanker, E.E., Dittmar, G., Fielitz, J. and Sommer, T.
Journal of Cell Science 132 (17): jcs233395. 6 September 2019

Dynamics of myosin degradation in intensive care unit-acquired weakness during severe critical illness.
Wollersheim, T., Woehlecke, J., Krebs, M., Hamati, J., Lodka, D., Luther-Schroeder, A., Langhans, C., Haas, K., Radtke, T., Kleber, C., Spies, C., Labeit, S., Schuelke, M., Spuler, S., Spranger, J., Weber-Carstens, S. and Fielitz, J.
Intensive Care Medicine 40 (4): 528-538. 15 February 2014

Muscle wasting and function after muscle activation and early protocol-based physiotherapy: an explorative trial.
Wollersheim, T., Grunow, J.J., Carbon, N.M., Haas, K., Malleike, J., Ramme, S.F., Schneider, J., Spies, C.D., Märdian, S., Mai, K., Spuler, S., Fielitz, J. and Weber-Carstens, S.
Journal of Cachexia Sarcopenia and Muscle 10 (4): 734-747. August 2019

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting.
Zanders, L., Kny, M., Hahn, A., Schmidt, S., Wundersitz, S., Todiras, M., Lahmann, I., Bandyopadhyay, A., Wollersheim, T., Kaderali, L., Luft, F.C., Birchmeier, C., Weber-Carstens, S. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 13 (1): 713-727. February 2021

Fischer, Christian (ECRC)

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.
Bono, F., De Smet, F., Herbert, C., De Bock, K., Georgiadou, M., Fons, P., Tjwa, M., Alcouffe, C., Ny, A., Bianciotto, M., Jonckx, B., Murakami, M., Lanahan, A.A., Michielsen, C., Sibrac, D., Dol-Gleizes, F., Mazzone, M., Zacchigna, S., Herault, J.P., Fischer, C., Rigon, P., Ruiz de Almodovar, C., Claes, F., Blanc, I., Poesen, K., Zhang, J., Segura, I., Gueguen, G., Bordes, M.F., Lambrechts, D., Broussy, R., van de Wouwer, M., Michaux, C., Shimada, T., Jean, I., Blacher, S., Noel, A., Motte, P., Rom, E., Rakic, J.M., Katsuma, S., Schaeffer, P., Yayon, A., Van Schepdael, A., Schwalbe, H., Gervasio, F.L., Carmeliet, G., Rozensky, J., Dewerchin, M., Simons, M., Christopoulos, A., Herbert, J.M. and Carmeliet, P.
Cancer Cell 23 (4): 477-488. 15 April 2013

Human granulocytic anaplasmosis acquired in Scotland, 2013.
Hagedorn, P., Imhoff, M., Fischer, C., Domingo, C. and Niedrig, M.
Emerging Infectious Diseases 20 (6): 1079-1081. June 2014

Placental growth factor supports neuroendocrine tumor growth and predicts disease prognosis in patients.
Hilfenhaus, G., Goehrig, A., Pape, U.F., Neumann, T., Jann, H., Zdunek, D., Hess, G., Stassen, J.M., Wiedenmann, B., Detjen, K., Pavel, M. and Fischer, C.
Endocrine-Related Cancer 20 (3): 305-319. 20 May 2013

Increased activity of the immunoregulatory enzyme indoleamine-2,3-dioxygenase (IDO) with consecutive tryptophan depletion predicts death in patients with neuroendocrine neoplasia.
Pschowski, R., Pape, U.F., Fusch, G., Fischer, C., Jann, H., Baur, A., Arsenic, R., Wiedenmann, B., von Haehling, S., Pavel, M. and Schefold, J.C.
Neuroendocrinology 104 (2): 135-144. December 2016

Forslund, Sofia (MDC/ECRC)

Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials.
Sun, M.L., Yao, W., Wang, X.Y., Gao, S., Varady, K.A., Forslund, S.K., Zhang, M., Shi, Z.Y., Cao, F., Zou, B.J., Sun, M.H., Liu, K.X., Bao, Q., Xu, J., Qin, X., Xiao, Q., Wu, L., Zhao, Y.H., Zhang, D.Y., Wu, Q.J. and Gong, T.T
EClinicalMedicine 70 : 102519. April 2024

Ganten, Detlev

Tissue and development specific expression of multiple alternatively spliced transcripts of rat neuronal nitric oxide synthase.
Lee, M.A., Cai, L., Hübner, N., Lee, Y.A. and Lindpaintner, K.
Journal of Clinical Investigation 100 (6): 1507-1512. 15 September 1997

Stammzellen.
Wormer, E.J., Kaufmann, W., Ganten, D. and Kempermann, G.
Themen der Zeit . Lingen Verl., Koeln. ISBN 3-937490-00-0 1 January 2003

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Özcelik, C., Erdmann, B., Pilz, B., Wettschureck, N., Britsch, S., Hübner, N., Chien, K.R., Birchmeier, C. and Garratt, A.N.
Proceedings of the National Academy of Sciences of the United States of America 99 (13): 8880-8885. 25 June 2002

Gargiulo, Gaetano

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S., Company, C., Song, K., Lowenstein, E.D., Riedel, L., Birchmeier, C., Gargiulo, G. and Zampieri, N.
Nature Communications 13 (1): 6867. 11 November 2022

Garratt, Alistair N.

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.
Atanasoski, S., Scherer, S.S., Sirkowski, E., Leone, D., Garratt, A.N., Birchmeier, C. and Suter, U.
Journal of Neuroscience 26 (7): 2124-2131. 15 February 2006