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2023

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor.
Aguirre, T. and Hostachy, S. and Dornan, G.L. and Neuenschwander, M. and Seyffarth, C. and Haucke, V. and Schütz, A. and von Kries, J.P. and Fiedler, D.
eLife 22 June 2023 (In Press)

The interleukin-11 receptor variant p.W307R results in craniosynostosis in humans.
Ahmad, I. and Lokau, J. and Kespohl, B. and Malik, N.A. and Baig, S.M. and Hartig, R. and Behme, D. and Schwab, R. and Altmüller, J. and Jameel, M. and Mucha, S. and Thiele, H. and Tariq, M. and Nürnberg, P. and Erdmann, J. and Garbers, C.
Scientific Reports 13 (1): 13479. 18 August 2023

The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions.
Ahmed, S.M. and Ragunathan, P. and Shin, J. and Peter, S. and Kleissle, S. and Neuenschwander, M. and Schäfer, R. and von Kries, J.P. and Grüber, G. and Dröge, P.
FEBS Letters 597 (15): 1977-1988. August 2023

Sites of transcription initiation drive mRNA isoform selection.
Alfonso-Gonzalez, C. and Legnini, I. and Holec, S. and Arrigoni, L. and Ozbulut, H.C. and Mateos, F. and Koppstein, D. and Rybak-Wolf, A. and Bönisch, U. and Rajewsky, N. and Hilgers, V.
Cell 186 (11): 2438-2455. 25 May 2023

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M. and Franke, V. and Benedum, J. and Grishkovskaya, I. and Strobl, X. and Polyansky, A. and Ammann, G. and Platzer, S. and Neudolt, A. and Wunder, A. and Walch, L. and Kaiser, S. and Zagrovic, B. and Djinovic-Carugo, K. and Akalin, A. and Slade, D.
Nature Communications 14 (1): 166. 11 January 2023

Expanding the spectrum of EEF1D neurodevelopmental disorders: biallelic variants in the guanine exchange domain.
Averdunk, L. and Al-Thihli, K. and Surowy, H. and Lüdecke, H.J. and Drechsler, M. and Yigit, G. and Smorag, L. and Hallak, B.A. and Li, Y. and Altmüller, J. and Guthoff, T. and Wallot, M. and Nürnberg, P. and Wollnik, B. and Abou Jamra, R. and Al-Maawali, A. and Wieczorek, D.
Clinical Genetics 103 (4): 484-491. April 2023

Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G. and Bartolomaeus, H. and Rauch, A. and Chen, C.Y. and N'Diaye, G. and Löber, U. and Bartolomaeus, T.U.P. and Fritsche-Guenther, R. and Rodrigues, A.F. and Yarritu, A. and Zhong, C. and Fei, L. and Tsvetkov, D. and Todiras, M. and Park, J.K. and Markó, L. and Maifeld, A. and Patzak, A. and Bader, M. and Kempa, S. and Kirwan, J.A. and Forslund, S.K. and Müller, D.N. and Wilck, N.
Cardiovascular Research 119 (6): 1441-1452. May 2023

Immune phenotypes and checkpoint molecule expression of clonally expanded lymph node-infiltrating T cells in classical Hodgkin lymphoma.
Ballhausen, A. and Ben Hamza, A. and Welters, C. and Dietze, K. and Bullinger, L. and Rahn, H.P. and Hartmann, S. and Hansmann, M.L. and Hansmann, L.
Cancer Immunology Immunotherapy 72 (2): 515-521. February 2023

Renal MRI: from nephron to NMR signal.
Bane, O. and Seeliger, E. and Cox, E. and Stabinska, J. and Bechler, E. and Lewis, S. and Hickson, L.T.J. and Francis, S. and Sigmund, E. and Niendorf, T.
Journal of Magnetic Resonance Imaging 26 May 2023 (In Press)

MRI of implantation sites using parallel transmission of an optimized radiofrequency excitation vector.
Berangi, M. and Kuehne, A. and Waiczies, H. and Niendorf, T.
Tomography 9 (2): 603-620. 8 March 2023

The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing.
Bischoff, N. and Wimberger, S. and Kuehn, R. and Laugesen, A. and Turan, V. and Larsen, B.D. and Sørensen, C.S. and Helin, K. and Bennett, E.P. and Maresca, M. and Brakebusch, C.
Gene and Genome Editing 5 : 100023. June 2023

A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A. and Haenig, C. and Neuendorf, N. and Blanc, E. and Ivanov, A. and Kirchner, M. and Schleumann, P. and Bayraktaroğlu, I. and Richter, M. and Molenda, C.M. and Sporbert, A. and Zenkner, M. and Schnoegl, S. and Suenkel, C. and Schneider, L.S. and Rybak-Wolf, A. and Kochnowsky, B. and Byrne, L.M. and Wild, E.J. and Nielsen, J.E. and Dittmar, G. and Peters, O. and Beule, D. and Wanker, E.E.
Genome Medicine 15 (1): 50. 20 July 2023

Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F. and Noerenberg, D. and Hennch, C. and Yoshida, K. and Hablesreiter, R. and Nimo, J. and Sasca, D. and Kirchner, M. and Mansouri, L. and Inoue, Y. and Wiegand, L. and Staiger, A.M. and Casadei, B. and Korkolopoulou, P. and Weiner, J. and Lopez-Guillermo, A. and Warth, A. and Schneider, T. and Nagy, Á. and Klapper, W. and Hummel, M. and Kanellis, G. and Anagnostopoulos, I. and Mertins, P. and Bullinger, L. and Rosenquist, R. and Vassilakopoulos, T.P. and Ott, G. and Ogawa, S. and Damm, F.
Leukemia 30 August 2023 (In Press)

LRP2 contributes to planar cell polarity-dependent coordination of motile cilia function.
Bunatyan, L. and Margineanu, A. and Boutin, C. and Montcouquiol, M. and Bachmann, S. and Christensen, E.I. and Willnow, T.E. and Christ, A.
Cell and Tissue Research 392 (2): 535-551. May 2023

LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome.
Busley, A.V. and Gutiérrez-Gutiérrez, O. and Hammer, E. and Steinegger, M. and Böhmer, L. and Schroeder, H. and Kleinsorge, M. and Altmüller, J. and Marbach, F. and Hasenfuss, G. and Zimmermann, W.H. and Wollnik, B. and Cyganek, L.
bioRxiv : 2023.01.10.523203. 10 January 2023

Monitoring kidney size to interpret MRI-based assessment of renal oxygenation in acute pathophysiological scenarios.
Cantow, K. and Gladytz, T. and Millward, J.M. and Waiczies, S. and Niendorf, T. and Seeliger, E.
Acta Physiologica 237 (2): e13868. February 2023

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R. and Conrad, T. and Stöber, M.C. and Xu, R. and Giurgiu, M. and Rodriguez-Fos, E. and Kasack, K. and Brückner, L. and van Leen, E. and Helmsauer, K. and Dorado Garcia, H. and Stefanova, M.E. and Hung, K.L. and Bei, Y. and Schmelz, K. and Lodrini, M. and Mundlos, S. and Chang, H.Y. and Deubzer, H.E. and Sauer, S. and Eggert, A. and Schulte, J.H. and Schwarz, R.F. and Haase, K. and Koche, R.P. and Henssen, A.G.
Nature Genetics 55 (5): 880-890. May 2023

Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Chee, J.M. and Lanoue, L. and Clary, D. and Higgins, K. and Bower, L. and Flenniken, A. and Guo, R. and Adams, D.J. and Bosch, F. and Braun, R.E. and Brown, S.D.M. and Chin, H.J.G. and Dickinson, M.E. and Hsu, C.W. and Dobbie, M. and Gao, X. and Galande, S. and Grobler, A. and Heaney, J.D. and Herault, Y. and de Angelis, M.H. and Mammano, F. and Nutter, L.M.J and Parkinson, H. and Qin, C. and Shiroishi, T. and Sedlacek, R. and Seong, J.K. and Xu, Y. and Brooks, B. and McKerlie, C. and Lloyd, K.C.K. and Westerberg, H. and Moshiri, A.
BMC Biology 21 (1): 22. 3 February 2023

Association of the human gut microbiota with vascular stiffness.
Cuadrat, R.R.C. and Goris, T. and Birukov, A. and Eichelmann, F. and Andrade, B.G.N. and Bang, C. and Franke, A. and Wittenbecher, C. and Schulze, M.B.
Scientific Reports 13 (1): 13348. 16 August 2023

Cardiovascular disease biomarkers derived from circulating cell-free DNA methylation.
Cuadrat, R.R.C. and Kratzer, A. and Arnal, H.G. and Rathgeber, A.C. and Wreczycka, K. and Blume, A. and Gündüz, I.B. and Ebenal, V. and Mauno, T. and Osberg, B. and Moobed, M. and Hartung, J. and Jakobs, K. and Seppelt, C. and Meteva, D. and Haghikia, A. and Leistner, D.M. and Landmesser, Ulf and Akalin, A.
NAR Genomics and Bioinformatics 5 (2): lqad061. June 2023

Bioactive phytochemicals from avocado oil processing by-products.
Cárdenas-Castro, A.P. and Fernández-Ochoa, Á. and Cádiz-Gurrea, M.d.l.L. and Segura Carretero, A. and Sáyago-Ayerdi, S.G.
In: Bioactive phytochemicals from vegetable oil and oilseed processing by-products. Reference Series in Phytochemistry, 1 . Springer, Cham, Switzerland, 403-430. ISBN 978-3-030-91380-9 22 March 2023

Old discovery leading to new era: metabolic imaging of cancer with Deuterium MRI.
Ding, H. and Haroon, A. and Wan, S. and Niendorf, T. and Adeleke, S.
Magnetochemistry 9 (1): 6. January 2023

Germline C1GALT1C1 mutation causes a multisystem chaperonopathy.
Erger, F. and Aryal, R.P. and Reusch, B. and Matsumoto, Y. and Meyer, R. and Zeng, J. and Knopp, C. and Noel, M. and Muerner, L. and Wenzel, A. and Kohl, S. and Tschernoster, N. and Rappl, G. and Rouvet, I. and Schröder-Braunstein, J. and Seibert, F.S. and Thiele, H. and Häusler, M.G. and Weber, L.T. and Büttner-Herold, M. and Elbracht, M. and Cummings, S.F. and Altmüller, J. and Habbig, S. and Cummings, R.D. and Beck, B.B.
Proceedings of the National Academy of Sciences of the United States of America 120 (22): e2211087120. 30 May 2023

Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging.
Espiritu, J. and Berangi, M. and Cwieka, H. and Iskhakova, K. and Kuehne, A. and Florian Wieland, D.C. and Zeller-Plumhoff, B. and Niendorf, T. and Willumeit-Römer, R. and Seitz, J.M.
Bioactive Materials 25 : 86-94. 23 January 2023

Spondyloarthritis, acute anterior uveitis, and Crohn's disease have both shared and distinct gut microbiota.
Essex, M. and Rios Rodriguez, V. and Rademacher, J. and Proft, F. and Löber, U. and Marko, L. and Pleyer, U. and Strowig, T. and Marchand, J. and Kirwan, J.A. and Siegmund, B. and Forslund, S.K. and Poddubnyy, D.
Arthritis & Rheumatology 20 July 2023 (In Press)

Machine learning-based ozone and PM2.5 forecasting: application to multiple AQS sites in the Pacific Northwest.
Fan, K. and Dhammapala, R. and Harrington, K. and Lamb, B. and Lee, Y.
Frontiers in Big Data 6 : 1124148. 24 February 2023

Metabolic syndrome and the risk of postoperative delirium and postoperative cognitive dysfunction: a multi-centre cohort study.
Feinkohl, I. and Janke, J. and Slooter, A.J.C. and Winterer, G. and Spies, C. and Pischon, T.
British Journal of Anaesthesia 131 (2): 338-347. August 2023

Identification of radiomic biomarkers in a set of four skeletal muscle groups on Dixon MRI of the NAKO MR study.
Fischer, M. and Küstner, T. and Pappa, S. and Niendorf, T. and Pischon, T. and Kröncke, T. and Bette, S. and Schramm, S. and Schmidt, B. and Haubold, J. and Nensa, F. and Nonnenmacher, T. and Palm, V. and Bamberg, F. and Kiefer, L. and Schick, F. and Yang, B.
BMC Medical Imaging 23 (1): 104. 8 August 2023

Potential contribution of ancient introgression to the evolution of a derived reproductive strategy in ricefishes.
Flury, J.M. and Meusemann, K. and Martin, S. and Hilgers, L. and Spanke, T. and Böhne, A. and Herder, F. and Mokodongan, D. and Altmüller, J. and Wowor, D. and Misof, B. and Nolte, A.W. and Schwarzer, J.
Genome Biology and Evolution 15 (8): evad138. 29 August 2023

TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients.
Foddis, M. and Blumenau, S. and Holtgrewe, M. and Paquette, K. and Westra, K. and Alonso, I. and Macario, M.d.C. and Morgadinho, A.S. and Velon, A.G. and Santo, G. and Santana, I. and Mönkäre, S. and Kuuluvainen, L. and Schleutker, J. and Pöyhönen, M. and Myllykangas, L. and Pavlovic, A. and Kostic, V. and Dobricic, V. and Lohmann, E. and Hanagasi, H. and Santos, M. and Guven, G. and Bilgic, B. and Bras, J. and Beule, D. and Dirnagl, U. and Guerreiro, R. and Sassi, C.
Neurobiology of Aging 123 : 208-215. March 2023

Advancements in pulsed stable isotope-resolved metabolomics.
Forbes, M. and Geisberger, S. and Pietzke, M. and Mastrobuoni, G. and Kempa, S.
Handbook of Experimental Pharmacology 277 : 165-180. 3 March 2023

A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O. and Jia, A. and Kuehn, H.S. and Min, Q. and Pannicke, U. and Schleussner, N. and Thouenon, R. and Yu, Z. and de Los Angeles Astbury, M. and Biggs, C.M. and Galicchio, M. and Garcia-Campos, J.A. and Gismondi, S. and Gonzalez Villarreal, G. and Hildebrand, K.J. and Hönig, M. and Hou, J. and Moshous, D. and Pittaluga, S. and Qian, X. and Rozmus, J. and Schulz, A.S. and Staines-Boone, A.T. and Sun, B. and Sun, J. and Uwe, S. and Venegas-Montoya, E. and Wang, W. and Wang, X. and Ying, W. and Zhai, X. and Zhou, Q. and Akalin, A. and André, I. and Barth, T.F.E. and Baumann, B. and Brüstle, A. and Burgio, G. and Bustamante, J.C. and Casanova, J.L. and Casarotto, M.G. and Cavazzana, M. and Chentout, L. and Cockburn, I.A. and Costanza, M. and Cui, C. and Daumke, O. and Del Bel, K.L. and Eibel, H. and Feng, X. and Franke, V. and Gebhardt, J.C.M. and Götz, A. and Grunwald, S. and Hoareau, B. and Hughes, T.R. and Jacobsen, E.M. and Janz, M. and Jolma, A. and Lagresle-Peyrou, C. and Lai, N. and Li, Y. and Lin, S. and Lu, H.Y. and Lugo-Reyes, S.O. and Meng, X. and Möller, P. and Moreno-Corona, N. and Niemela, J.E. and Novakovsky, G. and Perez-Caraballo, J.J. and Picard, C. and Poggi, L. and Puig-Lombardi, M.E. and Randall, K.L. and Reisser, A. and Schmitt, Y. and Seneviratne, S. and Sharma, M. and Stoddard, J. and Sundararaj, S. and Sutton, H. and Tran, L.Q. and Wang, Y. and Wasserman, W.W. and Wen, Z. and Winkler, W. and Xiong, E. and Yang, A.W.H. and Yu, M. and Zhang, L. and Zhang, H. and Zhao, Q. and Zhen, X. and Enders, A. and Kracker, S. and Martinez-Barricarte, R. and Mathas, S. and Rosenzweig, S.D. and Schwarz, K. and Turvey, S.E. and Wang, J.Y.
Science Immunology 8 (79): eade7953. January 2023

Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
Franz, A. and Weber, A.I. and Preußner, M. and Dimos, N. and Stumpf, A. and Ji, Y. and Moreno-Velasquez, L. and Voigt, A. and Schulz, F. and Neumann, A. and Kuropka, B. and Kuehn, R. and Urlaub, H. and Schmitz, D. and Wahl, M.C. and Heyd, F.
Life Science Alliance 6 (3): e202201826. March 2023

CAR links hypoxia signaling to improved survival after myocardial infarction.
Freiberg, F. and Thakkar, M. and Hamann, W. and Lopez Carballo, J. and Jüttner, R. and Voss, F.K. and Becher, P.M. and Westermann, D. and Tschöpe, C. and Heuser, A. and Rocks, O. and Fischer, R. and Gotthardt, M.
Experimental and Molecular Medicine 55 (3): 643-652. March 2023

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development.
Freitag, K. and Eede, P. and Ivanov, A. and Sterczyk, N. and Schneeberger, S. and Borodina, T. and Sauer, S. and Beule, D. and Heppner, F.L.
Communications Biology 6 (1): 40. 13 January 2023

Cesium activates the neurotransmitter receptor for glycine.
Fricke, S. and Harnau, M. and Hetsch, F. and Liu, H. and Leonhard, J. and Eylmann, A. and Knauff, P. and Sun, H. and Semtner, M. and Meier, J.C.
Frontiers in Molecular Neuroscience 16 : 1018530. 22 May 2023

Fiber-orientation independent component of R(2)* obtained from single-orientation MRI measurements in simulations and a post-mortem human optic chiasm.
Fritz, F.J. and Mordhorst, L. and Ashtarayeh, M. and Periquito, J. and Pohlmann, A. and Morawski, M. and Jaeger, C. and Niendorf, T. and Pine, K.J. and Callaghan, M.F. and Weiskopf, N. and Mohammadi, S.
Frontiers in Neuroscience 17 : 1133086. 25 August 2023

Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S. and Danßmann, C. and Klironomos, F. and Winkler, A. and Fallmann, J. and Kruetzfeldt, L.M. and Szymansky, A. and Naderi, J. and Bernhart, S.H. and Grunewald, L. and Helmsauer, K. and Rodriguez-Fos, E. and Kirchner, M. and Mertins, P. and Astrahantseff, K. and Suenkel, C. and Toedling, J. and Meggetto, F. and Remke, M. and Stadler, P.F. and Hundsdoerfer, P. and Deubzer, H.E. and Künkele, A. and Lang, P. and Fuchs, J. and Henssen, A.G. and Eggert, A. and Rajewsky, N. and Hertwig, F. and Schulte, J.H.
Nature Communications 14 (1): 3936. 4 July 2023

Better together: data harmonization and cross-study analysis of abdominal MRI data from UK Biobank and the German National Cohort.
Gatidis, S. and Kart, T. and Fischer, M. and Winzeck, S. and Glocker, B. and Bai, W. and Bülow, R. and Emmel, C. and Friedrich, L. and Kauczor, H.U. and Keil, T. and Kröncke, T. and Mayer, P. and Niendorf, T. and Peters, A. and Pischon, T. and Schaarschmidt, B.M. and Schmidt, B. and Schulze, M.B. and Umutle, L. and Völzke, H. and Küstner, T. and Bamberg, F. and Schölkopf, B. and Rueckert, D.
Investigative Radiology 58 (5): 346-354. 1 May 2023

Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function.
Geng, S. and Paul, F. and Kowalczyk, I. and Raimundo, S. and Sporbert, A. and Mamo, T.M. and Hammes, A.
Frontiers in Cell and Developmental Biology 11 : 1173688. 7 April 2023

"suMus," a novel digital system for arm movement metrics and muscle energy expenditure.
Gerhalter, Teresa and Müller, Christina and Maron, Elke and Thielen, Markus and Schätzl, Teresa and Mähler, A. and Schütte, T. and Boschmann, M. and Herzer, René and Spuler, S. and Gazzerro, E.
Frontiers in Physiology 14 : 1057592. 26 January 2023

A consensus protocol for functional connectivity analysis in the rat brain.
Grandjean, J. and Desrosiers-Gregoire, G. and Anckaerts, C. and Angeles-Valdez, D. and Ayad, F. and Barrière, D.A. and Blockx, I. and Bortel, A. and Broadwater, M. and Cardoso, B.M. and Célestine, M. and Chavez-Negrete, J.E. and Choi, S. and Christiaen, E. and Clavijo, P. and Colon-Perez, L. and Cramer, S. and Daniele, T. and Dempsey, E. and Diao, Y. and Doelemeyer, A. and Dopfel, D. and Dvořáková, L. and Falfán-Melgoza, C. and Fernandes, F.F. and Fowler, C.F. and Fuentes-Ibañez, A. and Garin, C.M. and Gelderman, E. and Golden, C.E.M. and Guo, C.C G. and Henckens, M.J.A.G. and Hennessy, L.A. and Herman, P. and Hofwijks, N. and Horien, C. and Ionescu, T.M. and Jones, J. and Kaesser, J. and Kim, E. and Lambers, H. and Lazari, A. and Lee, S.H. and Lillywhite, A. and Liu, Y. and Liu, Y.Y. and López-Castro, A. and López-Gil, X. and Ma, Z. and MacNicol, E. and Madularu, D. and Mandino, F. and Marciano, S. and McAuslan, M.J. and McCunn, P. and McIntosh, A. and Meng, X. and Meyer-Baese, L. and Missault, S. and Moro, F. and Naessens, D.M.P. and Nava-Gomez, L.J. and Nonaka, H. and Ortiz, J.J. and Paasonen, J. and Peeters, L.M. and Pereira, M. and Perez, P.D. and Pompilus, M. and Prior, M. and Rakhmatullin, R. and Reimann, H.M. and Reinwald, J. and Del Rio, R.T. and Rivera-Olvera, A. and Ruiz-Pérez, D. and Russo, G. and Rutten, T.J. and Ryoke, R. and Sack, M. and Salvan, P. and Sanganahalli, B.G. and Schroeter, A. and Seewoo, B.J. and Selingue, E. and Seuwen, A. and Shi, B. and Sirmpilatze, N. and Smith, J.A.B. and Smith, C. and Sobczak, F. and Stenroos, P.J. and Straathof, M. and Strobelt, S. and Sumiyoshi, A. and Takahashi, K. and Torres-García, M.E and Tudela, R. and van den Berg, M. and van der Marel, K. and van Hout, A.T.B. and Vertullo, R. and Vidal, B. and Vrooman, R.M. and Wang, V.X. and Wank, I. and Watson, D.J.G. and Yin, T. and Zhang, Y. and Zurbruegg, S. and Achard, S. and Alcauter, S. and Auer, D.P. and Barbier, E.L. and Baudewig, J. and Beckmann, C.F. and Beckmann, N. and Becq, G.J.P.C. and Blezer, E.L.A. and Bolbos, R. and Boretius, S. and Bouvard, S. and Budinger, E. and Buxbaum, J.D. and Cash, D. and Chapman, V. and Chuang, K.H. and Ciobanu, L. and Coolen, B.F. and Dalley, J.W. and Dhenain, M. and Dijkhuizen, R.M. and Esteban, O. and Faber, C. and Febo, M. and Feindel, K.W. and Forloni, G. and Fouquet, J. and Garza-Villarreal, E.A. and Gass, N. and Glennon, J.C. and Gozzi, A. and Gröhn, O. and Harkin, A. and Heerschap, A. and Helluy, X. and Herfert, K. and Heuser, A. and Homberg, J.R. and Houwing, D.J. and Hyder, F. and Ielacqua, G.D. and Jelescu, I.O. and Johansen-Berg, H. and Kaneko, G. and Kawashima, R. and Keilholz, S.D. and Keliris, G.A. and Kelly, C. and Kerskens, C. and Khokhar, J.Y. and Kind, P.C. and Langlois, J.B. and Lerch, J.P. and López-Hidalgo, M.A and Manahan-Vaughan, D. and Marchand, F. and Mars, R.B. and Marsella, G. and Micotti, E. and Muñoz-Moreno, E. and Near, J. and Niendorf, T. and Otte, W.M. and Pais-Roldán, P. and Pan, W.J. and Prado-Alcalá, R.A. and Quirarte, G.L. and Rodger, J. and Rosenow, T. and Sampaio-Baptista, C. and Sartorius, A. and Sawiak, S.J. and Scheenen, T.W.J. and Shemesh, N. and Shih, Y.Y.I. and Shmuel, A. and Soria, G. and Stoop, R. and Thompson, G.J. and Till, S.M. and Todd, N. and Van Der Linden, A. and van der Toorn, A. and van Tilborg, G.A.F and Vanhove, C. and Veltien, A. and Verhoye, M. and Wachsmuth, L. and Weber-Fahr, W. and Wenk, P. and Yu, X. and Zerbi, V. and Zhang, N. and Zhang, B.B. and Zimmer, L. and Devenyi, G.A. and Chakravarty, M.M. and Hess, A.
Nature Neuroscience 26 (4): 673-681. April 2023

Sex-specific microglia state in the neuroligin-4 knock-out mouse model of autism spectrum disorder.
Guneykaya, D. and Ugursu, B. and Logiacco, F. and Popp, O. and Feiks, M.A. and Meyer, N. and Wendt, S. and Semtner, M. and Cherif, F. and Gauthier, C. and Madore, C. and Yin, Z. and Çınar, Ö. and Arslan, T. and Gerevich, Z. and Mertins, P. and Butovsky, O. and Kettenmann, H. and Wolf, S.A.
Brain Behavior and Immunity 111 : 61-75. July 2023

Analysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort.
Haueise, T. and Schick, F. and Stefan, N. and Schlett, C.L. and Weiss, J.B. and Nattenmüller, J. and Göbel-Guéniot, K. and Norajitra, T. and Nonnenmacher, T. and Kauczor, H.U. and Maier-Hein, K.H. and Niendorf, T. and Pischon, T. and Jöckel, K.H. and Umutlu, L. and Peters, A. and Rospleszcz, S. and Kröncke, T. and Hosten, N. and Völzke, H. and Krist, L. and Willich, S.N. and Bamberg, F. and Machann, J.
Science Advances 9 (19): eadd0433. 12 May 2023

Generation of two mother-child pairs of iPSCs from maternally inherited Leigh syndrome patients with m.8993 T > G and m.9176 T > G MT-ATP6 mutations.
Henke, M.T. and Zink, A. and Diecke, S. and Prigione, A. and Schuelke, M.
Stem Cell Research 67 : 103030. March 2023

Accelerated simultaneous T2 and T2* mapping of multiple sclerosis lesions using compressed sensing reconstruction of radial RARE-EPI MRI.
Herrmann, C.J.J. and Starke, L. and Millward, J.M. and Kuchling, J. and Paul, F. and Niendorf, T.
Tomography 9 (1): 299-314. 31 January 2023

SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Heynen, G.J.J.E. and Baumgartner, F. and Heider, M. and Patra, U. and Holz, M. and Braune, J. and Kaiser, M. and Schäffer, I. and Bamopoulos, S.A. and Ramberger, E. and Murgai, A. and Ng, Y.L.D. and Demel, U.M. and Laue, D. and Liebig, S. and Krüger, J. and Janz, M. and Nogai, A. and Schick, M. and Mertins, P. and Müller, S. and Bassermann, F. and Krönke, J. and Keller, U. and Wirth, M.
Blood Advances 7 (4): 469-481. 28 February 2023

In vitro fertilization (IVF) program in white rhinoceros.
Hildebrandt, T.B. and Holtze, S. and Colleoni, S. and Hermes, R. and Stejskal, J. and Lekolool, I. and Ndereeh, D. and Omondi, P. and Kariuki, L. and Mijele, D. and Mutisya, S. and Ngulu, S. and Diecke, S. and Hayashi, K. and Lazzari, G. and de Mori, B. and Biasetti, P. and Quaggio, A. and Galli, C. and Goeritz, F.
Reproduction 1 September 2023 (In Press)

A hydraulic feedback loop between mesendoderm cell migration and interstitial fluid relocalization promotes embryonic axis formation in zebrafish.
Huljev, K. and Shamipour, S. and Pinheiro, D. and Preusser, F. and Steccari, I. and Sommer, C.M. and Naik, S. and Heisenberg, C.P.
Developmental Cell 58 (7): 582-596.e7. 10 April 2023

Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda et al.
Immisch, L. and Papafotiou, G. and Popp, O. and Mertins, P. and Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 11 (3): e006784. 14 March 2023

Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang, Q. and Stachelscheid, J. and Bloehdorn, J. and Pacholewska, A. and Aszyk, C.M. and Grotenhuijs, F. and Müller, T.A. and Onder, O. and Wagle, P. and Herling, C.D. and Kleppe, M. and Wang, Z. and Coombes, K.R. and Robrecht, S. and Dalvi, P.S. and Plosnita, B. and Mayer, P. and Abruzzo, L.V. and Altmüller, J. and Gathof, B.S. and Persigehl, T. and Fischer, K. and Jebaraj, B.M.C. and Rienhoff, H.Y. and Ecker, R.C. and Zhao, Y. and Bruns, C.J. and Stilgenbauer, S. and Elenitoba-Johnson, K.S.J. and Hallek, M. and Schweiger, M.R. and Odenthal, M. and Vasyutina, E. and Herling, M.
Blood 142 (1): 44-61. 6 July 2023

Small molecule specifically inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation.
Jordan, P. and Costa, A. and Specker, E. and Popp, O. and Volkamer, A. and Piske, R. and Obrusnik, T. and Kleissle, S. and Stuke, K. and Rex, A. and Neuenschwander, M. and von Kries, J.P. and Nazare, M. and Mertins, P. and Kettenmann, H. and Wolf, S.A.
PLoS ONE 18 (2): e0278325. 6 February 2023

IFNγ binding to extracellular matrix prevents fatal systemic toxicity.
Kemna, J. and Gout, E. and Daniau, L. and Lao, J. and Weißert, K. and Ammann, S. and Kühn, R. and Richter, M. and Molenda, C. and Sporbert, A. and Zocholl, D. and Klopfleisch, R. and Lortat-Jacob, H. and Aichele, P. and Kammertoens, T. and Blankenstein, T.
Nature Immunology 24 (3): 414-422. March 2023

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J. and Muinjonov, B. and Rosiewicz, K.S. and Diecke, S. and Biese, C. and Schiweck, J. and Chien, C. and Zocholl, D. and Conrad, T. and Paul, F. and Alisch, M. and Siffrin, V.
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

Translating metabolomics into clinical practice.
Kirwan, J.A.
Nature Reviews Bioengineering 1 : 228–229. April 2023

Studies in zebrafish and rat models support dual blockade of EP2 and EP4 (prostaglandin E(2) receptors type 2 and 4) for renoprotection in glomerular hyperfiltration and albuminuria.
Kourpa, A. and Schulz, A. and Mangelsen, E. and Kaiser-Graf, D. and Koppers, N. and Stoll, M. and Rothe, M. and Bader, M. and Purfürst, B. and Kunz, S. and Gladytz, T. and Niendorf, T. and Bachmann, S. and Mutig, K. and Bolbrinker, J. and Panakova, D. and Kreutz, R.
Hypertension 80 (4): 771-782. April 2023

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch, J. and Theisen, S. and Dartsch, J. and Fritsche-Guenther, R. and Kirchner, M. and Obermayer, B. and Bauer, A. and Kahlert, A.K. and Rothe, M. and Beule, D. and Heuser, A. and Mertins, P. and Kirwan, J.A. and Berndt, N. and MacRae, C.A. and Hubner, N. and Klaassen, S.
bioRxiv : 2023.01.10.523243. 10 January 2023

Germany's journey toward 14 Tesla human magnetic resonance.
Ladd, M.E. and Quick, H.H. and Speck, O. and Bock, M. and Doerfler, A. and Forsting, M. and Hennig, J. and Ittermann, B. and Möller, H.E. and Nagel, A.M. and Niendorf, T. and Remy, S. and Schaeffter, T. and Scheffler, K. and Schlemmer, H.P. and Schmitter, S. and Schreiber, L. and Shah, N.J. and Stöcker, T. and Uder, M. and Villringer, A. and Weiskopf, N. and Zaiss, M. and Zaitsev, M.
Magnetic Resonance Materials in Physics Biology and Medicine 36 (2): 191-210. April 2023

Estimates of protection levels against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season: the IMMUNEBRIDGE project.
Lange, B. and Jaeger, V.K. and Harries, M. and Rücker, V. and Streeck, H. and Blaschke, S. and Petersmann, A. and Toepfner, N. and Nauck, M. and Hassenstein, M.J. and Dreier, M. and von Holt, I. and Budde, A. and Bartz, A. and Ortmann, J. and Kurosinski, M.A. and Berner, R. and Borsche, M. and Brandhorst, G. and Brinkmann, M. and Budde, K. and Deckena, M. and Engels, G. and Fenzlaff, M. and Härtel, C. and Hovardovska, O. and Katalinic, A. and Kehl, K. and Kohls, M. and Krüger, S. and Lieb, W. and Meyer-Schlinkmann, K.M. and Pischon, T. and Rosenkranz, D. and Rübsamen, N. and Rupp, J. and Schäfer, C. and Schattschneider, M. and Schlegtendal, A. and Schlinkert, S. and Schmidbauer, L. and Schulze-Wundling, K. and Störk, S. and Tiemann, C. and Völzke, H. and Winter, T. and Klein, C. and Liese, J. and Brinkmann, F. and Ottensmeyer, P.F. and Reese, J.P. and Heuschmann, P. and Karch, A.
Infection 2 August 2023 (In Press)

Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini, I. and Emmenegger, L. and Zappulo, A. and Rybak-Wolf, A. and Wurmus, R. and Oliveras Martinez, A. and Cerda Jara, C. and Boltengagen, A. and Hessler, T. and Mastrobuoni, G. and Kempa, S. and Zinzen, R. and Woehler, A. and Rajewsky, N.
Nature Methods 21 September 2023 (In Press)

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.
Lin, M. and Hartl, K. and Heuberger, J. and Beccaceci, G. and Berger, H. and Li, H. and Liu, L. and Müllerke, S. and Conrad, T. and Heymann, F. and Woehler, A. and Tacke, F. and Rajewsky, N. and Sigal, M.
Nature Communications 14 (1): 3025. 25 May 2023

Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
Lo, W.T. and Belabed, H. and Kücükdisli, M. and Metag, J. and Roske, Y. and Prokofeva, P. and Ohashi, Y. and Horatscheck, A. and Cirillo, D. and Krauss, M. and Schmied, C. and Neuenschwander, M. and von Kries, J.P. and Médard, G. and Kuster, Be. and Perisic, O. and Williams, R.L. and Daumke, O. and Payrastre, B. and Severin, S. and Nazaré, M. and Haucke, V.
Nature Chemical Biology 19 (1): 18-27. January 2023

Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic.
Logiacco, F. and Grzegorzek, L.C. and Cordell, E.C. and Popp, O. and Mertins, P. and Gutmann, D.H. and Kettenmann, H. and Semtner, M.
Acta Neuropathologica Communications 11 (1): 36. 9 March 2023

Serum starvation accelerates intracellular metabolism in endothelial cells.
Lorenz, M. and Fritsche-Guenther, R. and Bartsch, C. and Vietzke, A. and Eisenberger, A. and Stangl, K. and Stangl, V. and Kirwan, J.A.
International Journal of Molecular Sciences 24 (2): 1189. 7 January 2023

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
Lowenstein, E.D. and Ruffault, P.L. and Misios, A. and Osman, K.L. and Li, H. and Greenberg, R.S. and Thompson, R. and Song, K. and Dietrich, S. and Li, X. and Vladimirov, N. and Woehler, A. and Brunet, J.F. and Zampieri, N. and Kühn, R. and Liberles, S.D. and Jia, S. and Lewin, G.R. and Rajewsky, N. and Lever, T.E. and Birchmeier, C.
Neuron 111 (14): 2184-2200.e7. 19 July 2023

ASSURED-optimized CRISPR protocol for knockout/SNP knockin in hiPSCs.
Ludwik, K.A. and Telugu, N. and Schommer, S. and Stachelscheid, H. and Diecke, S.
STAR Protocols 4 (3): 102406. 15 September 2023

Platelet-derived factors dysregulate placental sphingosine-1-phosphate receptor 2 in human trophoblasts.
Lyssy, F. and Guettler, J. and Brugger, B.A. and Stern, C. and Forstner, D. and Nonn, O. and Fischer, C. and Herse, F. and Wernitznig, S. and Hirschmugl, B. and Wadsack, C. and Gauster, M.
Reproductive BioMedicine Online 47 (2): 103215. August 2023

A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals.
Lázaro, J. and Costanzo, M. and Sanaki-Matsumiya, M. and Girardot, C. and Hayashi, M. and Hayashi, K. and Diecke, S. and Hildebrandt, T.B. and Lazzari, G. and Wu, J. and Petkov, S. and Behr, R. and Trivedi, V. and Matsuda, M. and Ebisuya, M.
Cell Stem Cell 30 (7): 938-949.e7. 6 July 2023

The genomic landscape across 474 surgically accessible epileptogenic human brain lesions.
López-Rivera, J.A. and Leu, C. and Macnee, M. and Khoury, J. and Hoffmann, L. and Coras, R. and Kobow, K. and Bhattarai, N. and Pérez-Palma, E. and Hamer, H. and Brandner, S. and Rössler, K. and Bien, C.G. and Kalbhenn, T. and Pieper, T. and Hartlieb, T. and Butler, E. and Genovese, G. and Becker, K. and Altmüller, J. and Niestroj, L.M. and Ferguson, L. and Busch, R.M. and Nürnberg, P. and Najm, I. and Blümcke, I. and Lal, D.
Brain 146 (4): 1342-1356. April 2023

A comprehensive molecular profiling approach reveals metabolic alterations that steer bone tissue regeneration.
Löffler, J. and Noom, A. and Ellinghaus, A. and Dienelt, A. and Kempa, S. and Duda, G.N.
Communications Biology 6 (1): 327. 27 March 2023

Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity.
Mangiante, L. and Alcala, N. and Sexton-Oates, A. and Di Genova, A. and Gonzalez-Perez, A. and Khandekar, A. and Bergstrom, E.N. and Kim, J. and Liu, X. and Blazquez-Encinas, R. and Giacobi, C. and Le Stang, N. and Boyault, S. and Cuenin, C. and Tabone-Eglinger, S. and Damiola, F. and Voegele, C. and Ardin, M. and Michallet, M.C. and Soudade, L. and Delhomme, T.M. and Poret, A. and Brevet, M. and Copin, M.C. and Giusiano-Courcambeck, S. and Damotte, D. and Girard, C. and Hofman, V. and Hofman, P. and Mouroux, J. and Cohen, C. and Lacomme, S. and Mazieres, J. and de Montpreville, V.T. and Perrin, C. and Planchard, G. and Rousseau, N. and Rouquette, I. and Sagan, C. and Scherpereel, A. and Thivolet, F. and Vignaud, J.M. and Jean, D. and Ilg, A.G.S. and Olaso, R. and Meyer, V. and Boland-Auge, A. and Deleuze, J.F. and Altmuller, J. and Nuernberg, P. and Ibáñez-Costa, A. and Castaño, J.P. and Lantuejoul, S. and Ghantous, A. and Maussion, C. and Courtiol, P. and Hernandez-Vargas, H. and Caux, C. and Girard, N. and Lopez-Bigas, N. and Alexandrov, L.B. and Galateau-Salle, F. and Foll, M. and Fernandez-Cuesta, L.
Nature Genetics 55 (4): 607-618. April 2023

Replicative aging impedes stress-induced assembly of a key human protein disaggregase.
Mathangasinghe, Y. and Alberts, N. and Rosado, C.J. and Cox, D. and Payne, N.L. and Ormsby, A.R. and Alp, K.M. and Sakson, R. and Uthishtran, S. and Ruppert, T. and Arumugam, S. and Hatters, D.M. and Kampinga, H.H. and Nillegoda, N.B.
bioRxiv : 2022.06.25.497591. 8 January 2023

Bioactive phytochemicals from sesame oil processing by-products.
Mekky, R.H. and Hegazy, M.M. and Cádiz-Gurrea, M.d.l.L. and Fernández-Ochoa, Á. and Segura Carretero, A.
In: Bioactive phytochemicals from vegetable oil and oilseed processing by-products. Reference Series in Phytochemistry, 1 . Springer, Cham, Switzerland, 155-194. ISBN 978-3-030-91380-9 22 March 2023

Massively parallel identification of mRNA localization elements in primary cortical neurons.
Mendonsa, S. and von Kügelgen, N. and Dantsuji, S. and Ron, M. and Breimann, L. and Baranovskii, A. and Lödige, I. and Kirchner, M. and Fischer, M. and Zerna, N. and Bujanic, L. and Mertins, P. and Ulitsky, I. and Chekulaeva, M.
Nature Neuroscience 26 (3): 394-405. March 2023

Human induced pluripotent stem cell-derived pericytes as scalable and editable source to study direct lineage reprogramming into induced neurons.
Menon, R. and Petrucci, L. and Lohrer, B. and Zhang, J. and Schulze, M. and Schichor, C. and Winner, B. and Winkler, J. and Riemenschneider, M.J. and Kühn, R. and Falk, S. and Karow, M.
Cellular Reprogramming 27 June 2023 (In Press)

Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection.
Mhlekude, B. and Postmus, D. and Stenzel, S. and Weiner, J. and Jansen, J. and Zapatero-Belinchón, F.J. and Olmer, R. and Richter, A. and Heinze, J. and Heinemann, N. and Mühlemann, B. and Schroeder, S. and Jones, T.C. and Müller, M.A. and Drosten, C. and Pich, A. and Thiel, V. and Martin, U. and Niemeyer, D. and Gerold, G. and Beule, D. and Goffinet, C.
PLoS Pathogens 19 (9): e1011657. 25 September 2023 (In Press)

Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence.
Miller, D.C. and Lisowski, P. and Genehr, C. and Wanker, E.E. and Priller, J. and Prigione, A. and Diecke, S.
Stem Cell Research 68 : 103056. April 2023

Sodium as an important regulator of immunometabolism.
Miyauchi, H. and Geisberger, S. and Luft, F.C. and Wilck, N. and Stegbauer, J. and Wiig, H. and Dechend, R. and Jantsch, J. and Kleinewietfeld, M. and Kempa, S. and Mueller, D.N.
Hypertension 7 September 2023 (In Press)

Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
Monsorno, K. and Ginggen, K. and Ivanov, A. and Buckinx, A. and Lalive, A.L. and Tchenio, A. and Benson, S. and Vendrell, M. and D'Alessandro, A. and Beule, D. and Pellerin, L. and Mameli, M. and Paolicelli, R.C.
Nature Communications 14 (1): 5749. 16 September 2023

Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19.
Mothes, R. and Pascual-Reguant, A. and Koehler, R. and Liebeskind, J. and Liebheit, A. and Bauherr, S. and Philipsen, L. and Dittmayer, C. and Laue, M. and von Manitius, R. and Elezkurtaj, S. and Durek, P. and Heinrich, F. and Heinz, G.A. and Guerra, G.M. and Obermayer, B. and Meinhardt, J. and Ihlow, J. and Radke, J. and Heppner, F.L. and Enghard, P. and Stockmann, H. and Aschman, T. and Schneider, J. and Corman, V.M. and Sander, L.E. and Mashreghi, M.F. and Conrad, T. and Hocke, A.C. and Niesner, R.A. and Radbruch, H. and Hauser, A.E.
Nature Communications 14 (1): 791. 11 February 2023

Bringing MRI to low- and middle-income countries: Directions, challenges and potential solutions.
Murali, S. and Ding, H. and Adedeji, F. and Qin, C. and Obungoloch, J. and Asllani, I. and Anazodo, U. and Ntusi, N.A.B. and Mammen, R. and Niendorf, T. and Adeleke, S.
NMR in Biomedicine : e4992. 4 July 2023 (In Press)

High-throughput metabolomics applications in pathogenesis and diagnosis of valvular heart disease.
Mutithu, D.W. and Kirwan, J.A. and Adeola, H.A. and Aremu, O.O. and Lumngwena, E.N. and Wiesner, L. and Skatulla, S. and Naidoo, R. and Ntusi, N.A.B.
Reviews in Cardiovascular Medicine 24 (6): 169. June 2023

The Berlin-Buch respiration chamber for energy expenditure measurements.
Mähler, A. and Schütte, T. and Steiniger, J. and Boschmann, M.
European Journal of Applied Physiology 123 (6): 1359-1368. June 2023

Instrumental drift in untargeted metabolomics: optimizing data quality with intrastudy QC samples.
Märtens, A. and Holle, J. and Mollenhauer, B. and Wegner, A. and Kirwan, J. and Hiller, K.
Metabolites 13 (5): 665. 16 May 2023

Salt sensitivity includes effects on immune cell signalling and metabolism.
Müller, D.N. and Geisberger, S. and Kleinewietfeld, M. and Jantsch, J.
Nature Reviews Immunology 23 (6): 341-342. June 2023

A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A. and Bakina, O. and Badillo Lisakowski, V. and Olivares-Chauvet, P. and Conrad, T. and Gotthardt, M. and Kettenmann, H. and Junker, J.P.
Molecular Systems Biology 19 (2): e11147. 10 February 2023

SODAR: managing multiomics study data and metadata.
Nieminen, M. and Stolpe, O. and Kuhring, M. and Weiner, J. and Pett, P. and Beule, D. and Holtgrewe, M.
GigaScience 12 : giad052. 27 July 2023

Disease- and sex-specific differences in patients with heart valve disease: a proteome study.
Nordmeyer, S. and Kraus, M. and Ziehm, M. and Kirchner, M. and Schafstedde, M. and Kelm, M. and Niquet, S. and Stephen, M.M. and Baczko, I. and Knosalla, C. and Schapranow, M.P. and Dittmar, G. and Gotthardt, M. and Falcke, M. and Regitz-Zagrosek, V. and Kuehne, T. and Mertins, P.
Life Science Alliance 6 (3): e202201411. March 2023

Radiofrequency antenna concepts for human cardiac MR at 14.0 T.
Nurzed, B. and Kuehne, A. and Aigner, C.S. and Schmitter, S. and Niendorf, T. and Eigentler, T.W.
Magnetic Resonance Materials in Physics Biology and Medicine 36 (2): 257-277. April 2023

Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation.
Obermayer, B. and Keilholz, L. and Conrad, T. and Frentsch, M. and Blau, I.W. and Vuong, L. and Lesch, S. and Movasshagi, K. and Tietze-Stolley, C. and Loyal, L. and Henze, L. and Penack, O. and Stervbo, U. and Babel, N. and Haas, S. and Beule, D. and Bullinger, L. and Wittenbecher, Friedrich and Na, I.K.
Frontiers in Immunology 14 : 1114368. 10 February 2023

Modeling of ACTN4-based podocytopathy using Drosophila nephrocytes.
Odenthal, J. and Dittrich, S. and Ludwig, V. and Merz, T. and Reitmeier, K. and Reusch, B. and Höhne, M. and Cosgun, Z.C. and Hohenadel, M. and Putnik, J. and Göbel, H. and Rinschen, M.M. and Altmüller, J. and Koehler, S. and Schermer, B. and Benzing, T. and Beck, B.B. and Brinkkötter, P.T. and Habbig, S. and Bartram, M.P.
Kidney International Reports 8 (2): 317-329. February 2023

Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study.
Pham, T.T. and Nimptsch, K. and Papadimitriou, N. and Aleksandrova, K. and Jenab, M. and Gunter, M.J. and Le Marchand, L. and Li, L. and Lynch, B.M. and Castellví-Bel, S. and Phipps, A.I. and Schmit, S.L. and Brenner, H. and Ogino, S. and Giovannucci, E. and Pischon, T.
Journal of Cancer Research and Clinical Oncology 21 August 2023 (In Press)

Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease.
Piwecka, M. and Rajewsky, N. and Rybak-Wolf, A.
Nature Reviews Neurology 19 (6): 346–362. June 2023

Targeted treatment in a case series of AR+, HRAS/PIK3CA co-mutated salivary duct carcinoma.
Rieke, D.T. and Schröder, S. and Schafhausen, P. and Blanc, E. and Zuljan, E. and von der Emde, B. and Beule, D. and Keller, U. and Keilholz, U. and Klinghammer, K.
Frontiers in Oncology 13 : 1107134. 2023

Mutational topography reflects clinical neuroblastoma heterogeneity.
Rodriguez-Fos, E. and Planas-Fèlix, M. and Burkert, M. and Puiggròs, M. and Toedling, J. and Thiessen, N. and Blanc, E. and Szymansky, A. and Hertwig, F. and Ishaque, N. and Beule, D. and Torrents, D. and Eggert, A. and Koche, R.P. and Schwarz, R.F. and Haase, K. and Schulte, J.H. and Henssen, A.G.
Cell Genomics : 100402. 7 September 2023 (In Press)

HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
Rosiewicz, K.S. and Muinjonov, B. and Kunz, S. and Radbruch, H. and Chen, J. and Jüttner, R. and Kerkering, J. and Ucar, J. and Crowley, T. and Wielockx, B. and Paul, F. and Alisch, M. and Siffrin, V.
Glia 71 (8): 2024-2044. August 2023

Genomic ALK alterations in primary and relapsed neuroblastoma.
Rosswog, C. and Fassunke, J. and Ernst, A. and Schömig-Markiefka, B. and Merkelbach-Bruse, S. and Bartenhagen, C. and Cartolano, M. and Ackermann, S. and Theissen, J. and Blattner-Johnson, M. and Jones, B. and Schramm, K. and Altmüller, J. and Nürnberg, P. and Ortmann, M. and Berthold, F. and Peifer, M. and Büttner, R. and Westermann, F. and Schulte, J.H. and Simon, T. and Hero, B. and Fischer, M.
British Journal of Cancer 128 (8): 1559-1571. 12 April 2023

Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.
Rybak-Wolf, A. and Wyler, E. and Pentimalli, T.M. and Legnini, I. and Oliveras Martinez, A. and Glažar, P. and Loewa, A. and Kim, S.J. and Kaufer, B.B. and Woehler, A. and Landthaler, M. and Rajewsky, N.
Nature Microbiology 8 (7): 1252-1266. July 2023

Advanced radio frequency applicators for thermal magnetic resonance theranostics of brain tumors.
Saha, N. and Kuehne, A. and Millward, J.M. and Eigentler, T.W. and Starke, L. and Waiczies, S. and Niendorf, T.
Cancers 15 (8): 2303. 14 April 2023

High fidelity 3D magnetic stray field mapping of smartphones to address safety considerations with active implantable electronic medical devices.
Saha, N. and Millward, J.M. and Herrmann, C.J.J. and Rahimi, F. and Han, H. and Lacour, P. and Blaschke, F. and Niendorf, T.
Sensors 23 (3): 1209. 20 January 2023

Transgenic angiotensin-converting enzyme 2 overexpression in the rat vasculature protects kidneys from ageing-induced injury.
Sanad, A.M. and Qadri, F. and Popova, E. and Rodrigues, A.F. and Heinbokel, T. and Quach, S. and Schulz, A. and Bachmann, S. and Kreutz, R. and Alenina, N. and Bader, M.
Kidney International 104 (2): 293-304. August 2023

Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.
Sandmann, C.L. and Schulz, J.F. and Ruiz-Orera, J. and Kirchner, M. and Ziehm, M. and Adami, E. and Marczenke, M. and Christ, A. and Liebe, N. and Greiner, J. and Schoenenberger, A. and Mücke, M.B. and Liang, N. and Moritz, R.L. and Sun, Z. and Deutsch, E.W. and Gotthardt, M. and Mudge, J.M. and Prensner, J.R. and Willnow, T.E. and Mertins, P. and van Heesch, S. and Hubner, N.
Molecular Cell 83 (6): 994-1011.e18. 16 March 2023

Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis.
Schaupp, L. and Addante, A. and Völler, M. and Fentker, K. and Kuppe, A. and Bardua, M. and Duerr, J. and Piehler, L. and Röhmel, J. and Thee, S. and Kirchner, M. and Ziehm, M. and Lauster, D. and Haag, R. and Gradzielski, M. and Stahl, M. and Mertins, P. and Boutin, S. and Graeber, S.Y. and Mall, M.A.
European Respiratory Journal 62 (2): 2202153. 1 August 2023

Scaling the mountains: what lies above 7 Tesla magnetic resonance?
Schmidt, R. and Keban, E. and Bollmann, S. and Wiggins, C.J. and Niendorf, T.
Magnetic Resonance Materials in Physics Biology and Medicine 36 (2): 151-157. April 2023

Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly.
Schnabel, F. and Schuler, E. and Al-Maawali, A. and Chaurasia, A. and Syrbe, S. and Al-Kindi, A. and Bhavani, G.S. and Shukla, A. and Altmüller, J. and Nürnberg, P. and Banka, S. and Girisha, K.M. and Li, Y. and Wollnik, B. and Yigit, G.
Human Genetics 142 (4): 543-552. April 2023

Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J. and Sundaravinayagam, D. and Blume, A. and Marg, A. and Grunwald, S. and Metzler, E. and Escobar, H. and Müthel, S. and Wang, H. and Wollersheim, T. and Weber-Carstens, S. and Akalin, A. and Di Virgilio, M. and Tursun, B. and Spuler, S.
International Journal of Molecular Sciences 24 (3): 2772. 1 February 2023

The genetic spectrum of congenital ocular motor apraxia type Cogan: an observational study, continued.
Schröder, S. and Yigit, G. and Li, Y. and Altmüller, J. and Büttel, H.M. and Fiedler, B. and Kretzschmar, C. and Nürnberg, P. and Seeger, J. and Serpieri, V. and Valente, E.M. and Wollnik, B. and Boltshauser, E. and Brockmann, K.
Orphanet Journal of Rare Diseases 18 (1): 101. 2 May 2023

A circular RNA expressed from the FAT3 locus regulates neural development.
Seeler, S. and Andersen, M.S. and Sztanka-Toth, T. and Rybiczka-Tešulov, M. and van den Munkhof, M.H. and Chang, C.C. and Maimaitili, M. and Venø, M.T. and Hansen, T.B. and Pasterkamp, R.J. and Rybak-Wolf, A. and Denham, M. and Rajewsky, N. and Kristensen, L.S. and Kjems, J.
Molecular Neurobiology 60 (6): 3239–3260. June 2023

Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A. and Walter, S. and Markó, L. and McMurray, B.J. and Sunaga-Franze, D.Y. and Xu, M. and Zühlke, K. and Russwurm, M. and Bartolomaeus, T.U.P. and Langanki, R. and Qadri, F. and Heuser, A. and Patzak, A. and Forslund, S.K. and Bähring, S. and Borodina, T. and Persson, P.B. and Maass, P.G. and Bader, M. and Klussmann, E.
Kidney International 104 (2): 388-393. August 2023

Thrifty energy phenotype predicts weight regain in postmenopausal women with overweight or obesity and is related to FGFR1 signaling.
Spranger, L. and Weiner, J. and Bredow, J. and Zeitz, U. and Grittner, U. and Boschmann, M. and Dickmann, S. and Stobäus, N. and Schwartzenberg, R.J. and Brachs, M. and Spranger, J. and Mai, K.
Clinical Nutrition 42 (4): 559-567. April 2023

First in vivo fluorine-19 magnetic resonance imaging of the multiple sclerosis drug siponimod.
Starke, L. and Millward, J.M. and Prinz, C. and Sherazi, F. and Waiczies, H. and Lippert, C. and Nazaré, M. and Paul, F. and Niendorf, T. and Waiczies, S.
Theranostics 13 (4): 1217-1234. 5 February 2023

Epigenetic regulation of plastin 3 expression by the macrosatellite DXZ4 and the transcriptional regulator CHD4.
Strathmann, E.A. and Hölker, I. and Tschernoster, N. and Hosseinibarkooie, S. and Come, J. and Martinat, C. and Altmüller, J. and Wirth, B.
American Journal of Human Genetics 110 (3): 442-459. 2 March 2023

Cytokines as potential novel therapeutic targets in severe inflammatory cardiomyopathy.
Suwalski, P. and Golpour, A. and Weiner, J. and Musigk, N. and Balzer, F. and Giesa, N. and Amr, A. and Trebing, J. and Sedaghat, F. and Meder, B. and Beule, D. and Landmesser, U. and Heidecker, B.
bioRxiv : 2023.07.27.23293253. 4 August 2023

Community survey results show that standardisation of preclinical imaging techniques remains a challenge.
Tavares, A.A.S. and Mezzanotte, L. and McDougald, W. and Bernsen, M.R. and Vanhove, C. and Aswendt, M. and Ielacqua, G.D. and Gremse, F. and Moran, C.M. and Warnock, G. and Kuntner, C. and Huisman, M.C.
Molecular imaging and biology 25 (3): 560-568. June 2023

Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
Torcal Garcia, G. and Kowenz-Leutz, E. and Tian, T.V and Klonizakis, A. and Lerner, J. and De Andres-Aguayo, L. and Sapozhnikova, V. and Berenguer, C. and Carmona, M.P. and Casadesus, M.V. and Bulteau, R. and Francesconi, M. and Peiro, S. and Mertins, P. and Zaret, K. and Leutz, A. and Graf, T.
eLife 12 : e83951. 27 June 2023

Application of a spacer-nick gene-targeting approach to repair disease-causing mutations with increased safety.
Tran, N.T. and Lebedin, M. and Danner, E. and Kühn, R. and Rajewsky, K. and Chu, V.T.
Bio-protocol 13 (8): e4661. 20 April 2023

The fate of oxidative strand breaks in mitochondrial DNA.
Trombly, G. and Said, A.M. and Kudin, A.P. and Peeva, V. and Altmüller, J. and Becker, K. and Köhrer, K. and Zsurka, G. and Kunz, W.S.
Antioxidants 12 (5): 1087. 12 May 2023

Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions.
Tschernoster, N. and Erger, F. and Kohl, S. and Reusch, B. and Wenzel, A. and Walsh, S. and Thiele, H. and Becker, C. and Franitza, M. and Bartram, M.P. and Kömhoff, M. and Schumacher, L. and Kukat, C. and Borodina, T. and Quedenau, C. and Nürnberg, P. and Rinschen, M.M. and Driller, J.H. and Pedersen, B.P. and Schlingmann, K.P. and Hüttel, B. and Bockenhauer, D. and Beck, B. and Altmüller, J.
Genome Medicine 15 (1): 62. 23 August 2023

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P. and Orgeur, M. and Comai, G. and Poehle-Kronnawitter, S. and Fischer, C. and Gloger, M. and Dumas, C.E. and Giesecke-Thiel, C. and Sauer, S. and Tajbakhsh, S. and Höpken, U.E. and Stricker, S.
Immunity 56 (6): 1204-1219. 13 June 2023

Associations of migration, socioeconomic position and social relations with depressive symptoms – analyses of the German National Cohort baseline data.
Vonneilich, N. and Becher, H. and Bohn, B. and Brandes, B. and Castell, S. and Deckert, A. and Dragano, N. and Franzke, C.W. and Führer, A. and Gastell, S. and Greiser, H. and Keil, T. and Klett-Tammen, C. and Koch-Gallenkamp, L. and Krist, L. and Leitzmann, M. and Meinke-Franze, C. and Mikolajczyk, R. and Moreno Velasquez, I. and Obi, N. and Peters, A. and Pischon, T. and Reuter, M. and Schikowski, T. and Schmidt, B. and Schulze, M. and Sergeev, D. and Stang, A. and Völzke, H. and Wiessner, C. and Zeeb, H. and Lüdecke, D. and von dem Knesebeck, O.
International Journal of Public Health 68 : 1606097. 18 July 2023

Gene editing in mouse zygotes using the CRISPR/Cas9 system.
Wefers, B. and Wurst, W. and Kühn, R.
Methods in Molecular Biology 2631 : 207-230. 2023

Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of adeno-associated virus vectors.
Westhaus, A. and Cabanes Creus, M. and Dilworth, K.L. and Zhu, E. and Salas, D. and Navarro, R.G. and Amaya, A.K. and Scott, A. and Kwiatek, M. and McCorkindale, A.L. and Hayman, T.E. and Frahm, A. and Perocheau, D. and Tran, B.M. and Vincan, E. and Wong, S.L. and Waters, S.A. and Riddiough, G.E. and Perini, M.V. and Wilson, L.O.W. and Baruteau, J. and Diecke, S. and Gonzalez-Aseguinolaza, G. and Santilli, G. and Thrasher, A.J. and Alexander, I.E. and Lisowski, L.
Human Gene Therapy 34 (7-8): 273-288. April 2023

Mouse models of human multiple myeloma subgroups.
Winkler, W. and Farré Díaz, C. and Blanc, E. and Napieczynska, H. and Langner, P. and Werner, M. and Walter, B. and Wollert-Wulf, B. and Yasuda, T. and Heuser, A. and Beule, D. and Mathas, S. and Anagnostopoulos, I. and Rosenwald, A. and Rajewsky, K. and Janz, M.
Proceedings of the National Academy of Sciences of the United States of America 120 (10): e2219439120. 7 March 2023

A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.
Xiong, E. and Popp, O. and Salomon, C. and Mertins, P. and Kocks, C. and Rajewsky, K. and Chu, V.T.
Frontiers in Immunology 13 : 1083119. 5 January 2023

Diagnostic and prognostic performance of renal compartment volume and the apparent diffusion coefficient obtained from magnetic resonance imaging in mild, moderate and severe diabetic kidney disease.
Zhao, K. and Li, S. and Liu, Y. and Li, Q. and Lin, H. and Wu, Z. and Seeliger, E. and Niendorf, T. and Liu, Z. and Wang, W.
Quantitative Imaging in Medicine and Surgery 13 (6): 3973-3987. 1 June 2023

Noninvasive assessment of diabetic kidney disease with MRI: hype or hope?
Zhao, K. and Seeliger, E. and Niendorf, T. and Liu, Z.
Journal of Magnetic Resonance Imaging 7 September 2023 (In Press)

Ablation of collagen XII disturbs joint extracellular matrix organization and causes patellar subluxation.
Zhu, M. and Metzen, F. and Hopkinson, M. and Betz, J. and Heilig, J. and Sodhi, J. and Imhof, T. and Niehoff, A. and Birk, D.E. and Izu, Y. and Krüger, M. and Pitsillides, A. A. and Altmüller, J. and van Osch, G.J.V.M. and Straub, V. and Schreiber, G. and Paulsson, M. and Koch, M. and Brachvogel, B.
iScience 26 (7): 107225. 21 July 2023

Prioritization of non-coding elements involved in non-syndromic cleft lip with/without cleft palate through genome-wide analysis of de novo mutations.
Zieger, H.K. and Weinhold, L. and Schmidt, A. and Holtgrewe, M. and Juranek, S.A. and Siewert, A. and Scheer, A.B. and Thieme, F. and Mangold, E. and Ishorst, N. and Brand, F.U. and Welzenbach, J. and Beule, D. and Paeschke, K. and Krawitz, P.M. and Ludwig, K.U.
Human Genetics and Genomics Advances 4 (1): 100166. 12 January 2023

Tumour mutational burden and survival with molecularly matched therapy.
de Bortoli, T. and Benary, M. and Horak, P. and Lamping, M. and Stintzing, S. and Tinhofer, I. and Leyvraz, S. and Schäfer, R. and Klauschen, F. and Keller, U. and Stenzinger, A. and Fröhling, S. and Kurzrock, R. and Keilholz, U. and Rieke, D.T. and Jelas, I.
European Journal of Cancer 190 : 112925. September 2023

The phenotypic and genotypic spectrum of epilepsy and intellectual disability in adults: Implications for genetic testing.
von Brauchitsch, S. and Haslinger, D. and Lindlar, S. and Thiele, H. and Bernsen, N. and Zahnert, F. and Reif, P.S. and Balcik, Y. and Au, P.Y.B. and Josephson, C. and Altmüller, J. and Strzelczyk, A. and Knake, S. and Rosenow, F. and Chiocchetti, A. and Klein, K.M.
Epilepsia Open 8 (2): 497-508. June 2023

2022

HDHL-INTIMIC: a European knowledge platform on food, diet, intestinal microbiomics, and human health.
Agamennone, V. and Abuja, P.M. and Basic, M. and De Angelis, M. and Gessner, A. and Keijser, B. and Larsen, M. and Pinart, M. and Nimptsch, K. and Pujos-Guillot, E. and Schlicht, K. and Sharon, I. and Untersmayr, E. and Laudes, M. and Pischon, T. and Bouwman, J.
Nutrients 14 (9): 1881. 29 April 2022

A novel MAP3K20 mutation causing centronuclear myopathy-6 with fiber-type disproportion in a Pakistani family.
Ahmad, I. and Khan, A. and Noor Ul Ayan, H. and Budde, B. and Altmüller, J. and Korejo, A.A. and Nürnberg, G. and Thiele, H. and Tariq, M. and Nürnberg, P. and Erdmann, J.
Journal of Human Genetics 11 October 2022

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H. and Flórez, A.F. and Kreth, S. and Brückner, L.M. and Yildiz, U. and Gartlgruber, M. and Odoni, D.I. and Poschet, G. and Garbowicz, K. and Shao, C. and Klein, C. and Meier, J. and Zeisberger, P. and Nadler-Holly, M. and Ziehm, M. and Paul, F. and Burhenne, J. and Bell, E. and Shaikhkarami, M. and Würth, R. and Stainczyk, S.A. and Wecht, E.M. and Kreth, J. and Büttner, M. and Ishaque, N. and Schlesner, M. and Nicke, B. and Stresemann, C. and Llamazares-Prada, M. and Reiling, J.H. and Fischer, M. and Amit, I. and Selbach, M. and Herrmann, C. and Wölfl, S. and Henrich, K.O. and Höfer, T. and Trumpp, A. and Westermann, F.
Nature Cancer 3 (4): 471-485. 28 April 2022

Single cell metabolism: current and future trends.
Ali, A. and Davidson, S. and Fraenkel, E. and Gilmore, I. and Hankemeier, T. and Kirwan, J.A. and Lane, A.N. and Lanekoff, I. and Larion, M. and McCall, L.I. and Murphy, M. and Sweedler, J.V. and Zhu, C.
Metabolomics 18 (10): 77. 1 October 2022

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C. and Acemel, R.D. and Jedamzick, J. and Bolondi, A. and Cova, G. and Brieske, N. and Kühn, R. and Wittler, L. and Real, F.M. and Lupiáñez, D.G.
Nature Genetics July 2022

The role of respiratory microbiota in the protection against viral diseases: respiratory commensal bacteria as next-generation probiotics for COVID-19.
Andrade, B.G.N. and Cuadrat, R.R.C. and Tonetti, F.R. and Kitazawa, H. and Villena, J.
Bioscience of Microbiota, Food and Health 41 (3): 94-102. 1 July 2022

De novo whole genome assembly of the Roborovski dwarf hamster (Phodopus roborovskii) genome, an animal model for severe/critical COVID-19.
Andreotti, S. and Altmüller, J. and Quedenau, C. and Borodina, T. and Nouailles, G. and Teixeira Alves, L.G. and Landthaler, M. and Bieniara, M. and Trimpert, J. and Wyler, E.
Genome Biology and Evolution 14 (7): evac100. July 2022

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M. and Grishkovskaya, I. and Benedum, J. and Franke, V. and Polyansky, A. and Neudolt, A. and Wunder, A. and Zagrovic, B. and Akalin, A. and Djinovic-Carugo, K. and Slade, D.
bioRxiv : 2022.02.26.482114. 27 February 2022

LABKIT: labeling and segmentation toolkit for big image data.
Arzt, M. and Deschamps, J. and Schmied, C. and Pietzsch, T. and Schmidt, D. and Tomancak, P. and Haase, R. and Jug, F.
Frontiers in Computer Science 4 : 777728. 10 February 2022

De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway.
Asif, M. and Kaygusuz, E. and Shinawi, M. and Nickelsen, A. and Hsieh, T.C. and Wagle, P. and Budde, B. and Hochscherf, J. and Abdullah, U. and Höning, S. and Nienberg, C. and Lindenblatt, D. and Noegel, A.A. and Altmüller, J. and Thiele, H. and Motameny, S. and Fleischer, N. and Segal, I. and Pais, L. and Tinschert, S. and Samra, N.G. and Savatt, J.M. and Rudy, N.L. and De Luca, C. and Fortugno, P. and White, S.M. and Krawitz, P. and Hurst, A.C.E. and Niefind, K. and Jose, J. and Brancati, F. and Nürnberg, P. and Hussain, M.S.
Human Genetics and Genomics Advances 3 (3): 100111. 14 July 2022

A novel missense variant of SCN4A co-segregates with congenital essential tremor in a consanguineous Kurdish family.
Asif, M. and Mocanu, I.D. and Abdullah, U. and Höhne, W. and Altmüller, J. and Makhdoom, E.U.H. and Thiele, H. and Baig, S.M. and Nürnberg, P. and Graul-Neumann, L. and Hussain, M.S.
American Journal of Medical Genetics A 188 (4): 1251-1258. April 2022

Selective endocytosis of Ca(2+)-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.
Azarnia Tehran, D. and Kochlamazashvili, G. and Pampaloni, N. P. and Sposini, S. and Shergill, J.K. and Lehmann, M. and Pashkova, N. and Schmidt, C. and Löwe, D. and Napieczynska, H. and Heuser, A. and Plested, A.J.R. and Perrais, D. and Piper, R.C. and Haucke, V. and Maritzen, T.
Science Advances 8 (21): eabl5032. 27 May 2022

RS-FISH: precise, interactive, fast, and scalable FISH spot detection.
Bahry, E. and Breimann, L. and Zouinkhi, M. and Epstein, L. and Kolyvanov, K. and Mamrak, N. and King, B. and Long, Xi and Harrington, K.I.S. and Lionnet, T. and Preibisch, S.
Nature Methods 19 (12): 1563-1567. December 2022

Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S. and Andreani, M. and Goncalves Andrade, J. and Saha, T. and Sundaravinayagam, D. and Garzón, J. and Zhang, W. and Popp, O. and Hiraga, S. and Rahjouei, A. and Rosen, D.B. and Mertins, P. and Chait, B.T. and Donaldson, A.D. and Di Virgilio, M.
eLife 11 : e75047. 13 April 2022

Aurora kinase A is involved in controlling the localization of aquaporin-2 in renal principal cells.
Baltzer, S. and Bulatov, T. and Schmied, C. and Krämer, A. and Berger, B.T. and Oder, A. and Walker-Gray, R. and Kuschke, C. and Zühlke, K. and Eichhorst, J. and Lehmann, M. and Knapp, S. and Weston, J. and von Kries, J.P. and Süssmuth, R.D. and Klussmann, E.
International Journal of Molecular Sciences 23 (2): 763. 11 January 2022

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D. and Hörtenhuber, M. and Balwierz, P.J. and Zehnder, T. and Mukarram, A.K. and Nepal, C. and Várnai, C. and Hadzhiev, Y. and Jimenez-Gonzalez, A. and Li, N. and Wragg, J. and D'Orazio, F.M. and Relic, D. and Pachkov, M. and Díaz, N. and Hernández-Rodríguez, B. and Chen, Z. and Stoiber, M. and Dong, M. and Stevens, I. and Ross, S.E. and Eagle, A. and Martin, R. and Obasaju, O. and Rastegar, S. and McGarvey, A.C. and Kopp, W. and Chambers, E. and Wang, D. and Kim, H.R. and Acemel, R.D. and Naranjo, S. and Łapiński, M. and Chong, V. and Mathavan, S. and Peers, B. and Sauka-Spengler, T. and Vingron, M. and Carninci, P. and Ohler, U. and Lacadie, S.A. and Burgess, S.M. and Winata, C. and van Eeden, F. and Vaquerizas, J.M. and Gómez-Skarmeta, J.L. and Onichtchouk, D. and Brown, B.J. and Bogdanovic, O. and van Nimwegen, E. and Westerfield, M. and Wardle, F.C and Daub, C.O. and Lenhard, B. and Müller, F.
Nature Genetics 54 (7): 1037-1050. July 2022

Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A. and Gündüz, I.B. and Franke, V. and Uyar, B. and Akalin, A.
Cancers 14 (22): 5604. 15 November 2022

PyZebraScope: an open-source platform for brain-wide neural activity imaging in zebrafish.
Barbara, R. and Nagathihalli Kantharaju, M. and Haruvi, R. and Harrington, K. and Kawashima, T.
Frontiers in Cell and Developmental Biology 10 : 875044. 19 May 2022

PyZebraScope: an open-source platform for brain-wide neural activity imaging in zebrafish.
Barbara, R. and Nagathihalli Kantharaju, M. and Haruvi, R. and Harrington, K. and Kawashima, T.
bioRxiv : bioRxiv. 15 February 2022

Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics.
Bayram, S. and Razzaque, Y.S. and Geisberger, S. and Pietzke, M. and Fürst, S. and Vechiatto, C. and Forbes, M. and Mastrobuoni, G. and Kempa, S.
Frontiers in Molecular Biosciences 9 : 859787. 12 August 2022

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G. and Blume, A. and Demirel, F.G. and Bulut, S. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 73 (1): 5-17. June 2022

Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 72 (5): 175-184. May 2022

The single-cell transcriptional landscape of lung carcinoid tumors.
Bischoff, P. and Trinks, A. and Wiederspahn, J. and Obermayer, B. and Pett, J.P. and Jurmeister, P. and Elsner, A. and Dziodzio, T. and Rückert, J.C. and Neudecker, J. and Falk, C. and Beule, D. and Sers, C. and Morkel, M. and Horst, D. and Klauschen, F. and Blüthgen, N.
International Journal of Cancer 150 (12): 2058-2071. 15 June 2022

Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T. and Funck, K. and Wollweber, F. and Lisicki, E. and von der Malsburg, K. and von der Malsburg, A. and Laborenz, J. and Noel, J.K. and Hessenberger, M. and Jungbluth, S. and Bernert, C. and Kunz, S. and Riedel, D. and Lilie, H. and Jakobs, S. and van der Laan, M. and Daumke, O.
Science Advances 8 (35): eabo4946. 2 September 2022

Full-length spatial transcriptomics reveals the unexplored isoform diversity of the myocardium post-MI.
Boileau, E. and Li, X. and Naarmann-de Vries, I.S. and Becker, C. and Casper, R. and Altmüller, J. and Leuschner, F. and Dieterich, C.
Frontiers in Genetics 13 : 912572. 22 July 2022

Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways.
Braun, T. and Glass, M. and Wahnschaffe, L. and Otte, M. and Mayer, P. and Franitza, M. and Altmüller, J. and Hallek, M. and Hüttelmaier, S. and Schrader, A. and Herling, M.
Haematologica 107 (1): 187-200. January 2022

Noncanonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemia.
Braun, T. and Stachelscheid, J. and Bley, N. and Oberbeck, S. and Otte, M. and Müller, T.A. and Wahnschaffe, L. and Glaß, M. and Ommer, K. and Franitza, M. and Gathof, B. and Altmüller, J. and Hallek, M. and Auguin, D. and Hüttelmaier, S. and Schrader, A. and Herling, M.
Cancer Research 82 (9): 1818-1831. 1 May 2022

Claudin-10a deficiency shifts proximal tubular Cl(-) permeability to cation selectivity via claudin-2 redistribution.
Breiderhoff, T. and Himmerkus, N. and Meoli, L. and Fromm, A. and Sewerin, S. and Kriuchkova, N. and Nagel, O. and Ladilov, Y. and Krug, S. and Quintanova, C. and Stumpp, M. and Garbe-Schönberg, D. and Westernströer, U. and Merkel, C. and Brinkhus, M. and Altmüller, J. and Schweiger, M. and Mueller, D. and Mutig, K. and Morawski, M. and Halbritter, J. and Milatz, S. and Bleich, M. and Günzel, D.
Journal of the American Society of Nephrology 33 (4): 699-717. April 2022

The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L. and Morao, A.K. and Kim, J. and Jimenez, D.S. and Maryn, N. and Bikkasani, K. and Carrozza, M.J. and Albritton, S.E. and Kramer, M. and Street, L.A. and Cerimi, K. and Schumann, V.F. and Bahry, E. and Preibisch, S. and Woehler, A. and Ercan, S.
Journal of Cell Science 135 (2): jcs258818. January 2022

WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephaly.
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Human Mutation 43 (10): 1454-1471. October 2022

Single cell‐ and spatial 'omics revolutionize physiology.
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Acta Physiologica : e13848. 2 June 2022

Combining callers improves the detection of copy number variants from whole-genome sequencing.
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European Journal of Human Genetics 30 (2): 178-186. February 2022

Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases.
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Metabolic Engineering 72 : 116-132. July 2022

Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19.
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Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
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Human Molecular Genetics 31 (23): 3945-3966. 1 December 2022

A comparison of solvent-based extraction methods to assess the central carbon metabolites in mouse bone and muscle.
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Metabolites 12 (5): 453. 18 May 2022

Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
Dieckmann, S. and Strohmeyer, A. and Willershäuser, M. and Maurer, S.F. and Wurst, W. and Marschall, S. and Hrabě de Angelis, M. and Kühn, R. and Worthmann, A. and Fuh, M.M. and Heeren, J. and Köhler, N. and Pauling, J.K. and Klingenspor, M.
American Journal of Physiology Endocrinology and Metabolism 322 (2): E85-E100. February 2022

Identifying tumor cells at the single-cell level using machine learning.
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Genome Biology 23 (1): 123. 30 May 2022

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
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Nature Communications 13 (1): 4297. 25 July 2022

Increase in mental disorders during the COVID-19 pandemic -- the role of occupational and financial strains. An analysis of the German National Cohort (NAKO) Study.
Dragano, N. and Reuter, M. and Peters, A. and Engels, M. and Schmidt, B. and Greiser, K.H. and Bohn, B. and Riedel-Heller, S. and Karch, A. and Mikolajczyk, R. and Krause, G. and Lang, O. and Panreck, L. and Rietschel, M. and Brenner, H. and Fischer, B. and Franzke, C.W. and Gastell, S. and Holleczek, B. and Jöckel, K.H. and Kaaks, R. and Keil, T. and Kluttig, A. and Kuß, O. and Legath, N. and Leitzmann, M. and Lieb, W. and Meinke-Franze, C. and Michels, K.B. and Obi, N. and Pischon, T. and Feinkohl, I. and Rospleszcz, S. and Schikowski, T. and Schulze, M.B. and Stang, A. and Völzke, H. and Willich, S.N. and Wirkner, K. and Zeeb, H. and Ahrens, W. and Berger, K.
Deutsches Arzteblatt International 119 (11): 179-187. 18 March 2022

Uncovering the contribution of moderate-penetrance susceptibility genes to breast cancer by whole-exome sequencing and targeted enrichment sequencing of candidate genes in women of European ancestry.
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Cancers 14 (14): 3363. 11 July 2022

Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.
Dzamukova, M. and Brunner, T.M. and Miotla-Zarebska, J. and Heinrich, F. and Brylka, L. and Mashreghi, M.F. and Kusumbe, A. and Kühn, R. and Schinke, T. and Vincent, T.L.. and Löhning, M.
Nature Communications 13 (1): 3059. 1 June 2022

C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages.
Dörr, D. and Obermayer, B. and Weiner, J.M. and Zimmermann, K. and Anania, C. and Wagner, L.K. and Lyras, E.M. and Sapozhnikova, V. and Lara-Astiaso, D. and Prósper, F. and Lang, R. and Lupiáñez, D.G. and Beule, D. and Höpken, U.E. and Leutz, A. and Mildner, A.
Science Immunology 7 (75): eabj0140. September 2022

Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
Ebert, M.J. and Jerke, U. and Eulenberg-Gustavus, C. and Kling, L. and Jenne, D.E. and Kirchner, M. and Mertins, P. and Bieringer, M. and Elitok, S. and Eckardt, K.U. and Schreiber, A. and Salama, A.D. and Kettritz, R.
Journal of Clinical Investigation 132 (23): e160089. 1 December 2022

The anti-glucocorticoid receptor antibody clone 5E4: raising awareness of unspecific antibody binding.
Ehlers, L. and Kirchner, M. and Mertins, P. and Strehl, C. and Buttgereit, F. and Gaber, T.
International Journal of Molecular Sciences 23 (9): 5049. 2 May 2022

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
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Circulation 146 (23): 1758-1778. 6 December 2022

Evaluating metallic artefact of biodegradable magnesium-based implants in magnetic resonance imaging.
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Bioactive Materials 15 : 382-391. September 2022

Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in severe COVID-19.
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bioRxiv : 2022.12.02.518860. 2 December 2022

Development of a machine learning approach for local-scale ozone forecasting: application to Kennewick, WA.
Fan, K. and Dhammapala, R. and Harrington, K. and Lamastro, R. and Lamb, B. and Lee, Y.
Frontiers in Big Data 5 : 781309. 10 February 2022

One gene - two proteins: the C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria.
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bioRxiv : 2021.04.13.438299. 26 February 2022

Recent analytical approaches for the study of bioavailability and metabolism of bioactive phenolic compounds.
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Molecules 27 (3): 777. 25 January 2022

Comprehensive identification of plant polyphenols by LC-MS.
Fernández-Ochoa, Á. and de la Luz Cádiz-Gurrea, M. and Segura Carretero, A.
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Presurgical diffusion metrics of the thalamus and thalamic nuclei in postoperative delirium: a prospective two-centre cohort study in older patients.
Fislage, M. and Winzeck, S. and Stamatakis, E. and Correia, M.M. and Preller, J. and Feinkohl, I. and Spies, C.D. and Hendrikse, J. and J.C Slooter, A. and Winterer, G. and Pischon, T. and Menon, D.K. and Zacharias, N.
NeuroImage: Clinical 36 : 103208. 2022

The SCF/KIT axis in human mast cells: capicua acts as potent KIT repressor and ERK predominates PI3K.
Franke, K. and Kirchner, M. and Mertins, P. and Zuberbier, T. and Babina, M.
Allergy 77 (11): 3337-3349. November 2022

Branch point evolution controls species-specific alternative splicing and regulates long term potentiation.
Franz, A. and Weber, A.I. and Preußner, M. and Dimos, N. and Stumpf, A. and Ji, Y. and Moreno-Velasquez, L. and Voigt, A. and Schulz, F. and Neumann, A. and Kuropka, B. and Kühn, R. and Urlaub, H. and Schmitz, D. and Wahl, M.C. and Heyd, F.
bioRxiv : 2022.09.09.507289. 11 September 2022

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development.
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Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model.
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Rational design of highly potent, selective, and bioavailable SGK1 protein kinase inhibitors for the treatment of osteoarthritis.
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Robust induction of primordial germ cells of white rhinoceros on the brink of extinction.
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Inflammation and convergent placenta gene co-option contributed to a novel reproductive tissue.
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Uncoupling the excitatory amino acid transporter 2 from its C-terminal interactome restores synaptic glutamate clearance at corticostriatal synapses and alleviates mutant huntingtin-induced hypokinesia.
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Human alveolar progenitors generate dual lineage bronchioalveolar organoids.
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Effects of separated pair housing of female C57BL/6JRj mice on well-being.
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Inflammation in children with chronic kidney disease linked to gut dysbiosis and metabolite imbalance.
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Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.
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Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
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H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2(+) patients with diffuse midline glioma.
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Analyses of circRNA expression throughout the light-dark cycle reveal a strong regulation of (Cdr1as), associated with light entrainment in the SCN.
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Non-redundant functions of group 2 innate lymphoid cells.
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Prediction of activity-related energy expenditure under free-living conditions using accelerometer-derived physical activity.
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DNA methylation-based classification of sinonasal tumors.
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A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts.
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(RB1)-negative retinal organoids display proliferation of cone photoreceptors and loss of retinal differentiation.
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Automated imaging-based abdominal organ segmentation and quality control in 20,000 participants of the UK Biobank and German National Cohort Studies.
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Nonproductive exposure of PBMCs to SARS‐CoV ‐2 induces cell‐intrinsic innate immune responses.
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Placental transcriptome profiling in subtypes of diabetic pregnancies is strongly confounded by fetal sex.
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Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
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Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
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Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management.
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Association of ultra-rare coding variants with genetic generalized epilepsy: a case-control whole exome sequencing study.
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Regional gene expression patterns are associated with task-specific brain activation during reward and emotion processing measured with functional MRI.
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Simultaneous dimensionality reduction and integration for single-cell ATAC-seq data using deep learning.
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15-keto-Prostaglandin E(2) exhibits bioactive role by modulating glomerular cytoarchitecture through EP2/EP4 receptors.
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Computational approaches to predicting treatment response to obesity using neuroimaging.
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A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse.
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Paracrine interleukin 6 induces cerebral remodeling at early stages after unilateral common carotid artery occlusion in mice.
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Genome engineering in rodents - status quo and perspectives.
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Magnetic field-induced interactions between phones containing magnets and cardiovascular implantable electronic devices: Flip it to be safe?
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Interleukin 8 in postoperative delirium - preliminary findings from two studies.
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Alport syndrome and autosomal dominant tubulointerstitial kidney disease frequently underlie end stage renal disease of unknown origin - a single center analysis.
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Nephrology Dialysis Transplantation 37 (10): 1895-1905. 22 September 2022

Spatio-temporal, optogenetic control of gene expression in organoids.
Legnini, I. and Emmenegger, L. and Zappulo, A. and Wurmus, R. and Oliveras Martinez, A. and Cerda Jara, C. and Boltengagen, A. and Hessler, T. and Mastrobuoni, G. and Rybak-Wolf, A. and Kempa, S. and Zinzen, R.P. and Woehler, A. and Rajewsky, N.
bioRxiv : 2021.09.26.461850v3. 9 February 2022

A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies.
Lessel, D. and Rading, K. and Campbell, S.E. and Thiele, H. and Altmüller, J. and Gordon, L.B. and Kubisch, C.
American Journal of Medical Genetics A 188 (1): 216-223. January 2022

Introducing the Molecular Pharmaceutics special issue on “tiny things, big impact: nanomedicine in Canada”.
Li, S.D. and Wasan, E. and Bally, M. and Hedtrich, S.
Molecular Pharmaceutics 19 (6): 1657-1658. 6 June 2022

High-content analysis of neuronal morphology in human iPSC-derived neurons.
Lickfett, S. and Menacho, C. and Zink, A. and Telugu, N.S. and Beller, M. and Diecke, S. and Cambridge, S. and Prigione, A.
STAR Protocols 3 (3): 101567. 16 September 2022

Diffusion-weighted magnetic resonance imaging in rat kidney using two-dimensional navigated, interleaved echo-planar imaging at 7.0 T.
Liu, Q. and Xu, Z. and Zhao, K. and Hoge, W.S. and Zhang, X. and Mei, Y. and Lu, Q. and Niendorf, T. and Feng, Y.
NMR in Biomedicine 35 (5): e4652. May 2022

Tongue immune compartment analysis reveals spatial macrophage heterogeneity.
Lyras, E.M. and Zimmermann, K. and Wagner, L.K. and Dörr, D. and Klose, C.S.N and Fischer, C. and Jung, S. and Yona, S. and Hovav, A.H. and Stenzel, W. and Dommerich, S. and Conrad, T. and Leutz, A. and Mildner, A.
eLife 11 : 77490. 24 June 2022

Impact of metabolic stress induced by diets, aging and fasting on tissue oxygen consumption.
Mackert, O. and Wirth, E.K. and Sun, R. and Winkler, J. and Liu, A. and Renko, K. and Kunz, S. and Spranger, J. and Brachs, S.
Molecular Metabolism 64 : 101563. October 2022

The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation towards the kidney lineage.
Mansour, F. and Hinze, C. and Telugu, N.S. and Kresoja, J. and Shaheed, I.B. and Mosimann, C. and Diecke, S. and Schmidt-Ott, K.M.
eLife 11 : e80165. 12 October 2022

Genomic variants reducing expression of two endocytic receptors in 46,XY differences of sex development.
Marko, H.L. and Hornig, N.C. and Betz, R.C. and Holterhus, P.M. and Altmüller, J. and Thiele, H. and Fabiano, M. and Schweikert, H.U. and Braun, D. and Schweizer, U.
Human Mutation 43 (3): 420-433. March 2022

ClearCNV: CNV calling from NGS panel data in the presence of ambiguity and noise.
May, V. and Koch, L. and Fischer-Zirnsak, B. and Horn, D. and Gehle, P. and Kornak, U. and Beule, D. and Holtgrewe, M.
Bioinformatics 38 (16): 3871-3876. 15 August 2022

Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
McGarvey, A.C. and Kopp, W. and Vučićević, D. and Mattonet, K. and Kempfer, R. and Hirsekorn, A. and Bilić, I. and Gil, M. and Trinks, A. and Merks, A.M. and Panáková, D. and Pombo, A. and Akalin, A. and Junker, J.P. and Stainier, D.Y.R. and Garfield, D. and Ohler, U. and Lacadie, S.A.
Cell Genomics 2 (1): 100083. 13 January 2022

Reliable assessment of telomere maintenance mechanisms in neuroblastoma.
Meeser, A. and Bartenhagen, C. and Werr, L. and Hellmann, A.M. and Kahlert, Y. and Hemstedt, N. and Nürnberg, P. and Altmüller, J. and Ackermann, S. and Hero, B. and Simon, T. and Peifer, M. and Fischer, M. and Rosswog, C.
Cell and Bioscience 12 (1): 160. 24 September 2022

Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T. and Lindemann, P. and Welle, A. and Trouillet, V. and Heißler, S. and Nazaré, M. and Selbach, M.
ChemMedChem 17 (19): e202200346. 6 October 2022

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A. and Sprink, T. and Noel, J.K. and Vázquez-Sarandeses, E. and van Hoorn, C. and Mohd, S. and Loerke, J. and Spahn, C.M.T. and Daumke, O.
Nature Communications 13 (1): 7641. 10 December 2022

Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E. and Escobar, H. and Sunaga-Franze, D.Y. and Sauer, S. and Diecke, S. and Spuler, S.
Biomedicines 10 (5): 1204. 23 May 2022

Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C. and Lisowski, P. and Lickfett, S. and Mlody, B. and Bünning, M. and Genehr, C. and Ulrich, C. and Wanker, E.E. and Diecke, S. and Priller, J. and Prigione, A.
Stem Cell Research 65 : 102976. December 2022

Genomic basis of syndromic short stature in an Algerian patient cohort.
Moosa, S. and Chentli, F. and Altmüller, J. and Bögershausen, N. and Nürnberg, P. and Yigit, G. and Li, Y. and Wollnik, B.
American Journal of Medical Genetics A 188 (2): 606-612. February 2022

Political knowledge and misinformation in the era of social media: evidence from the 2015 UK election.
Munger, K. and Egan, P.J. and Nagler, J. and Ronen, J. and Tucker, J.
British Journal of Political Science 52 (1): 107 - 127. January 2022

Increased salt intake decreases diet-induced thermogenesis in healthy volunteers: a randomized placebo-controlled study.
Mähler, A. and Klamer, S. and Maifeld, A. and Bartolomaeus, H. and Markó, L. and Chen, C.Y. and Forslund, S.K. and Boschmann, M. and Müller, D.N. and Wilck, N.
Nutrients 14 (2): 253. 7 January 2022

Mediterranean diet and atrial fibrillation: lessons learned from the AFHRI case-control study.
Neumann, F.A. and Jagemann, B. and Makarova, N. and Börschel, C.S. and Aarabi, G. and Gutmann, F. and Schnabel, R.B. and Zyriax, B.C.
Nutrients 14 (17): 3615. 1 September 2022

Candesartan does not activate PPAR(γ) and its target genes in early gestation trophoblasts.
Neuper, L. and Kummer, D. and Forstner, D. and Guettler, J. and Ghaffari-Tabrizi-Wizsy, N. and Fischer, C. and Juch, H. and Nonn, O. and Gauster, M.
International Journal of Molecular Sciences 23 (20): 12326. October 2022

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D. and Ramberger, E. and Bohl, S.R. and Dolnik, A. and Steinebach, C. and Conrad, T. and Müller, S. and Popp, O. and Kull, M. and Haji, M. and Gütschow, M. and Döhner, H. and Walther, W. and Keller, U. and Bullinger, L. and Mertins, P. and Krönke, J.
Nature Communications 13 (1): 1009. 23 February 2022

Generation of a NES-mScarlet red fluorescent reporter human iPSC line for live cell imaging and flow cytometric analysis and sorting using CRISPR-Cas9-mediated gene editing.
Nouri, P. and Zimmer, A. and Brüggemann, S. and Friedrich, R. and Kühn, R. and Prakash, N.
Cells 11 (2): 268. 13 January 2022

Urbanization promotes specific bacteria in freshwater microbiomes including potential pathogens.
Numberger, D. and Zoccarato, L. and Woodhouse, J. and Ganzert, L. and Sauer, S. and García Márquez, J.R. and Domisch, S. and Grossart, H.P. and Greenwood, A.D.
Science of the Total Environment 845 : 157321. 1 November 2022

Effect of atmospheric aging on soot particle toxicity in lung cell models at the air-liquid interface: differential toxicological impacts of biogenic and anthropogenic secondary organic aerosols (SOAs).
Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Martens, P. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Pardo, M. and Gröger, T. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Rudich, Y. and Zimmermann, R.
Environmental Health Perspectives 130 (2): 27003. 3 February 2022

Lack of evidence for participation of TMEM150C in sensory mechanotransduction.
Ojeda-Alonso, J. and Bégay, V. and Garcia-Contreras, J.A. and Campos-Pérez, A.F. and Purfürst, B. and Lewin, G.R.
Journal of General Physiology 154 (12): e202213098. 5 December 2022

Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla, T. and Gollasch, B. and Kuich, P.H.J.L. and Klug, L. and Rahn, G. and Busjahn, A. and Spuler, S. and Boschmann, M. and Kirwan, J.A. and Luft, F.C. and Kempa, S.
Frontiers in Molecular Biosciences 9 : 1042231. 21 December 2022

Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.
Ortiz-Zapater, E. and Bagley, D.C. and Hernandez, V.L. and Roberts, L.B. and Maguire, T.J.A. and Voss, F. and Mertins, P. and Kirchner, M. and Peset-Martin, I. and Woszczek, G. and Rosenblatt, J. and Gotthardt, M. and Santis, G. and Parsons, M.
Nature Communications 13 (1): 6407. 27 October 2022

A computational model for prediction of ferritin and haemoglobin levels in blood donors.
Paalvast, Y. and Moazzen, S. and Sweegers, M. and Hogema, B. and Janssen, M. and van den Hurk, K.
British Journal of Haematology 199 (1): 143-152. October 2022

Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells.
Pardo, M. and Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Schneider, E. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Karg, E. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Shalit, T. and Gröger, T. and Rüger, C.P. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Zimmermann, R. and Rudich, Y.
Environment International 166 : 107366. 21 June 2022 (In Press)

A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
Patsalos, A. and Halasz, L. and Medina-Serpas, M.A. and Berger, W.K. and Daniel, B. and Tzerpos, P. and Kiss, M. and Nagy, G. and Fischer, C. and Simandi, Z. and Varga, T. and Nagy, L.
Journal of Experimental Medicine 219 (1): e20210420. 3 January 2022

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K. and Leunig, A. and Kaiser, R. and Joppich, M. and Brambs, S. and Janjic, A. and Popp, O. and Nixdorf, D. and Fumagalli, V. and Schmidt, N. and Polewka, V. and Anjum, A. and Knottenberg, V. and Eivers, L. and Wange, L.E. and Gold, C. and Kirchner, M. and Muenchhoff, M. and Hellmuth, J.C. and Scherer, C. and Rubio-Acero, R. and Eser, T. and Deák, F. and Puchinger, K. and Kuhl, N. and Linder, A. and Saar, K. and Tomas, L. and Schulz, C. and Wieser, A. and Enard, W. and Kroidl, I. and Geldmacher, C. and von Bergwelt-Baildon, M. and Keppler, O.T. and Munschauer, M. and Iannacone, M. and Zimmer, R. and Mertins, P. and Hubner, N. and Hoelscher, M. and Massberg, S. and Stark, K. and Nicolai, L.
Nature Communications 13 (1): 1018. 23 February 2022

A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics.
Pennitz, P. and Kirsten, H. and Friedrich, V.D. and Wyler, E. and Goekeri, C. and Obermayer, B. and Heinz, G.A. and Mashreghi, M.F. and Büttner, M. and Trimpert, J. and Landthaler, M. and Suttorp, N. and Hocke, A.C. and Hippenstiel, S. and Tönnies, M. and Scholz, M. and Kuebler, W.M. and Witzenrath, M. and Hoenzke, K. and Nouailles, G.
European Respiratory Review 31 (165): 220056. 30 September 2022

Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Perea-Gil, I. and Seeger, T. and Bruyneel, A.A.N. and Termglinchan, V. and Monte, E. and Lim, E.W. and Vadgama, N. and Furihata, T. and Gavidia, A.A. and Arthur Ataam, J. and Bharucha, N. and Martinez-Amador, N. and Ameen, M. and Nair, P. and Serrano, R. and Kaur, B. and Feyen, D.A.M. and Diecke, S. and Snyder, M.P. and Metallo, C.M. and Mercola, M. and Karakikes, I.
European Heart Journal 43 (36): 3477-3489. 21 September 2022

Framework and baseline examination of the German National Cohort (NAKO).
Peters, A. and Peters, A. and Greiser, K.H. and Göttlicher, S. and Ahrens, W. and Albrecht, M. and Bamberg, F. and Bärnighausen, T. and Becher, H. and Berger, K. and Beule, A. and Boeing, H. and Bohn, B. and Bohnert, K. and Braun, B. and Brenner, H. and Bülow, R. and Castell, S. and Damms-Machado, A. and Dörr, M. and Ebert, N. and Ecker, M. and Emmel, C. and Fischer, B. and Franzke, C.W. and Gastell, S. and Giani, G. and Günther, M. and Günther, K. and Günther, K.P. and Haerting, J. and Haug, U. and Heid, I.M. and Heier, M. and Heinemeyer, D. and Hendel, T. and Herbolsheimer, F. and Hirsch, J. and Hoffmann, W. and Holleczek, B. and Hölling, H. and Hörlein, A. and Jöckel, K.H. and Kaaks, R. and Karch, A. and Karrasch, S. and Kartschmit, N. and Kauczor, H.U. and Keil, T. and Kemmling, Y. and Klee, B. and Klüppelholz, B. and Kluttig, A. and Kofink, L. and Köttgen, A. and Kraft, D. and Krause, G. and Kretz, L. and Krist, L. and Kühnisch, J. and Kuß, O. and Legath, N. and Lehnich, A.T. and Leitzmann, M. and Lieb, W. and Linseisen, J. and Loeffler, M. and Macdonald, A. and Maier-Hein, K.H. and Mangold, N. and Meinke-Franze, C. and Meisinger, C. and Melzer, J. and Mergarten, B. and Michels, K.B. and Mikolajczyk, R. and Moebus, S. and Mueller, U. and Nauck, M. and Niendorf, T. and Nikolaou, K. and Obi, N. and Ostrzinski, S. and Panreck, L. and Pigeot, I. and Pischon, T. and Pschibul-Thamm, I. and Rathmann, W. and Reineke, A. and Roloff, S. and Rujescu, D. and Rupf, S. and Sander, O. and Schikowski, T. and Schipf, S. and Schirmacher, P. and Schlett, C.L. and Schmidt, B. and Schmidt, G. and Schmidt, M. and Schöne, G. and Schulz, H. and Schulze, M.B. and Schweig, A. and Sedlmeier, A.M. and Selder, S. and Six-Merker, J. and Sowade, R. and Stang, A. and Stegle, O. and Steindorf, K. and Stübs, G. and Swart, E. and Teismann, H. and Thiele, I. and Thierry, S. and Ueffing, M. and Völzke, H. and Waniek, S. and Weber, A. and Werner, N. and Wichmann, H.E. and Willich, S.N. and Wirkner, K. and Wolf, K. and Wolff, R. and Zeeb, H. and Zinkhan, M. and Zschocke, J.
European Journal of Epidemiology 37 (10): 1107-1124. October 2022

A RAS-independent biomarker panel to reliably predict response to MEK inhibition in colorectal cancer.
Pfohl, U. and Loskutov, J. and Bashir, S. and Kühn, R. and Herter, P. and Templin, M. and Mamlouk, S. and Belanov, S. and Linnebacher, M. and Bürtin, F. and Vetter, M. and Reinhard, C. and Wedeken, L. and Regenbrecht, C.R.A.
Cancers 14 (13): 3252. 1 July 2022

Pre-diagnostic circulating resistin concentrations are not associated with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study.
Pham, T.T. and Nimptsch, K. and Aleksandrova, K. and Jenab, M. and Reichmann, R. and Wu, K. and Tjønneland, A. and Kyrø, C. and Schulze, M.B. and Kaaks, R. and Katzke, V. and Palli, D. and Pasanisi, F. and Ricceri, F. and Tumino, R. and Krogh, V. and Roodhart, J. and Castilla, J. and Sánchez, M.J. and Colorado-Yohar, S.M. and Harbs, J. and Rutegård, M. and Papier, K. and Aglago, E.K. and Dimou, N. and Mayen-Chacon, A.L. and Weiderpass, E. and Pischon, T.
Cancers 14 (22): 5499. 9 November 2022

RNA modification mapping with JACUSA2.
Piechotta, M. and Naarmann-de Vries, I.S. and Wang, Q. and Altmüller, J. and Dieterich, C.
Genome Biology 23 (1): 115. 16 May 2022

Long-term imaging reveals behavioral plasticity during C. elegans dauer exit.
Preusser, F. and Neuschulz, A. and Junker, J.P. and Rajewsky, N. and Preibisch, S.
bioRxiv : 2022.04.25.489360v1. 26 April 2022

Sustainable low-field cardiovascular magnetic resonance in changing healthcare systems.
Qin, C. and Murali, S. and Lee, E. and Supramaniam, V. and Hausenloy, D.J. and Obungoloch, J. and Brecher, J. and Lin, R. and Ding, H. and Akudjedu, T.N. and Anazodo, U.C. and Jagannathan, N.R. and Ntusi, N.A.B. and Simonetti, O.P. and Campbell-Washburn, A.E. and Niendorf, T. and Mammen, R. and Adeleke, S.
European Heart Journal - Cardiovascular Imaging : jeab286. 14 February 2022

Radiofrequency antenna helmet array for thermal magnetic resonance of brain tumours at 297 MHz.
Rahimi, F. and Berangi, M. and Eigentler, T.W. and Nurzed, B. and Millward, J.M. and Schuhmann, R. and Niendorf, T.
In: 2022 3rd URSI Atlantic and Asia Pacific Radio Science Meeting (AT-AP-RASC), 30 May - 04 Jun 2022, Gran Canaria, Spain. 6 July 2022

EBAG9 controls CD8(+) T cell memory formation responding to tumor challenge in mice.
Rehm, A. and Wirges, A. and Hoser, D. and Fischer, C. and Herda, S. and Gerlach, K. and Sauer, S. and Willimsky, G. and Hoepken, U.E.
JCI Insight 7 (11): e155534. 8 June 2022

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies.
Reichart, D. and Lindberg, E.L. and Maatz, H. and Miranda, A.M.A. and Viveiros, A. and Shvetsov, N. and Gärtner, A. and Nadelmann, E.R. and Lee, M. and Kanemaru, K. and Ruiz-Orera, J. and Strohmenger, V. and DeLaughter, D.M. and Patone, G. and Zhang, H. and Woehler, A. and Lippert, C. and Kim, Y. and Adami, E. and Gorham, J.M. and Barnett, S.N. and Brown, K. and Buchan, R.J. and Chowdhury, R.A. and Constantinou, C. and Cranley, J. and Felkin, L.E. and Fox, H. and Ghauri, A. and Gummert, J. and Kanda, M. and Li, R. and Mach, L. and McDonough, B. and Samari, S. and Shahriaran, F. and Yapp, C. and Stanasiuk, C. and Theotokis, P.I. and Theis, F.J. and van den Bogaerdt, A. and Wakimoto, H. and Ware, J.S. and Worth, C.L. and Barton, P.J.R. and Lee, Y.A. and Teichmann, S.A. and Milting, H. and Noseda, M. and Oudit, G.Y. and Heinig, M. and Seidman, J.G. and Hubner, N. and Seidman, C.E.
Science 377 (6606): eabo1984. 5 August 2022

MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells.
Reusch, B. and Bartram, M.P. and Dafinger, C. and Palacio-Escat, N. and Wenzel, A. and Fenton, R.A. and Saez-Rodriguez, J. and Schermer, B. and Benzing, T. and Altmüller, J. and Beck, B.B. and Rinschen, M.M.
Journal of Proteomics 252 : 104424. 10 February 2022

Biallelic PAN2 variants in individuals with a syndromic neurodevelopmental disorder and multiple congenital anomalies.
Reuter, M.S. and Zech, M. and Hempel, M. and Altmüller, J. and Heung, T. and Pölsler, L. and Santer, R. and Thiele, H. and Trost, B. and Kubisch, C. and Scherer, S.W. and Rudnik-Schöneborn, S. and Bassett, A.S. and Lessel, D.
European Journal of Human Genetics 30 (5): 611-618. May 2022

Feasibility and outcome of reproducible clinical interpretation of high-dimensional molecular data: a comparison of two molecular tumor boards.
Rieke, D.T. and de Bortoli, T. and Horak, P. and Lamping, M. and Benary, M. and Jelas, I. and Rüter, G. and Berger, J. and Zettwitz, M. and Kagelmann, N. and Kind, A. and Fabian, F. and Beule, D. and Glimm, H. and Brors, B. and Stenzinger, A. and Fröhling, S. and Keilholz, U.
BMC Medicine 20 (1): 367. 24 October 2022

Hypoxia differentially affects healthy men and women during a daytime nap with a dose-response relationship: a randomized, cross-over pilot study.
Riveros-Rivera, A. and Penzel, T. and Gunga, H.C. and Opatz, O. and Paul, F. and Klug, L. and Boschmann, M. and Mähler, A.
Frontiers in Physiology 13 : 899636. 24 May 2022

Prevalence of cancer predisposition germline variants in male breast cancer patients: results of the German Consortium for Hereditary Breast and Ovarian Cancer.
Rolfes, M. and Borde, J. and Möllenhoff, K. and Kayali, M. and Ernst, C. and Gehrig, A. and Sutter, C. and Ramser, J. and Niederacher, D. and Horváth, J. and Arnold, N. and Meindl, A. and Auber, B. and Rump, A. and Wang-Gohrke, S. and Ritter, J. and Hentschel, J. and Thiele, H. and Altmüller, J. and Nürnberg, P. and Rhiem, K. and Engel, C. and Wappenschmidt, B. and Schmutzler, R.K. and Hahnen, E. and Hauke, J.
Cancers 14 (13): 3292. 5 July 2022

Serum dihydrotestosterone is associated with adverse myocardial remodeling in patients with aortic valve stenosis before and after aortic valve replacement.
Schafstedde, M. and Nordmeyer, J. and Berger, F. and Knosalla, C. and Mertins, P. and Regitz-Zagrosek, V. and Kuehne, T. and Kraus, M. and Nordmeyer, S.
American Journal of Physiology Heart and Circulatory Physiology 323 (5): H949-H957. November 2022

Adolescence is a sensitive period for prefrontal microglia to act on cognitive development.
Schalbetter, S.M. and von Arx, A.S. and Cruz-Ochoa, N. and Dawson, K. and Ivanov, A. and Mueller, F.S. and Lin, H.Y. and Amport, R. and Mildenberger, W. and Mattei, D. and Beule, D. and Földy, C. and Greter, M. and Notter, T. and Meyer, U.
Science Advances 8 (9): eabi6672. 4 March 2022

Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice.
Schepanski, S. and Chini, M. and Sternemann, V. and Urbschat, C. and Thiele, K. and Sun, T. and Zhao, Y. and Poburski, M. and Woestemeier, A. and Thieme, M.T. and Zazara, D.E. and Alawi, M. and Fischer, N. and Heeren, J. and Vladimirov, N. and Woehler, A. and Puelles, V.G. and Bonn, S. and Gagliani, N. and Hanganu-Opatz, I.L. and Arck, P.C.
Nature Communications 13 (1): 4571. 5 August 2022

Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance.
Schlautmann, L.P. and Lackmann, J.W. and Altmüller, J. and Dieterich, C. and Boehm, V. and Gehring, N.H.
Nucleic Acids Research 50 (10): 5899-5918. 10 June 2022

Somatic mosaicism in STAG2-associated cohesinopathies: Expansion of the genotypic and phenotypic spectrum.
Schmidt, J. and Dreha-Kulaczewski, S. and Zafeiriou, M.P. and Schreiber, M.K. and Wilken, B. and Funke, R. and Neuhofer, C.M. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Biskup, S. and Li, Y. and Zimmermann, W.H. and Kaulfuß, S. and Yigit, G. and Wollnik, B.
Frontiers in Cell and Developmental Biology 10 : 1025332. 16 November 2022

Familial cleft tongue caused by a unique translation initiation codon variant in TP63.
Schmidt, J. and Schreiber, G. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Li, Y. and Kaulfuß, S. and Funke, R. and Wilken, B. and Yigit, G. and Wollnik, B.
European Journal of Human Genetics 30 (2): 211-218. February 2022

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F. and de Castro Cuadrat, R.R. and Wyler, E. and Wurmus, R. and Deter, A. and Quedenau, C. and Dohmen, J. and Faxel, M. and Borodina, T. and Blume, A. and Freimuth, J. and Meixner, M. and Grau, J.H. and Liere, K. and Hackenbeck, T. and Zietzschmann, F. and Gnirss, R. and Böckelmann, U. and Uyar, B. and Franke, V. and Barke, N. and Altmüller, J. and Rajewsky, N. and Landthaler, M. and Akalin, A.
Science of the Total Environment 853 : 158931. 20 December 2022

Whole-body magnetic resonance imaging in the large population-based German National Cohort study: predictive capability of automated image quality assessment for protocol repetitions.
Schuppert, C. and von Krüchten, R. and Hirsch, J.G. and Rospleszcz, S. and Hoinkiss, D.C. and Selder, S. and Köhn, A. and von Stackelberg, O. and Peters, A. and Völzke, H. and Kröncke, T. and Niendorf, T. and Forsting, M. and Hosten, N. and Hendel, T. and Pischon, T. and Jöckel, K.H. and Kaaks, R. and Bamberg, F. and Kauczor, H.U. and Günther, M. and Schlett, C.L.
Investigative Radiology 57 (7): 478-487. 1 July 2022

Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine.
Schwab, K. and Chasapopoulou, Z. and Frahm, S. and Magbagbeolu, M. and Cranston, A. and Harrington, C.R. and Wischik, C.M. and Theuring, F. and Riedel, G.
Cellular Signalling 97 : 110386. September 2022

Eating patterns during pregnancy and postpartum and their association with diet quality and energy intake.
Schwedhelm, C. and Lipsky, L.M. and Temmen, C.D. and Nansel, T.R.
Nutrients 14 (6): 1167. 10 March 2022

3D-printed tissue-simulating phantoms for near-infrared fluorescence imaging of rheumatoid diseases.
Schädel-Ebner, S. and Hirsch, O. and Gladytz, T. and Gutkelch, D. and Licha, K. and Berger, J. and Grosenick, D.
Journal of Biomedical Optics 27 (7): 074702. July 2022

Pathogenic variants in cardiomyopathy disorder genes underlie pediatric myocarditis - Further impact of heterozygous immune disorder gene variants?
Seidel, F. and Laser, K.T. and Klingel, K. and Dartsch, J. and Theisen, S. and Pickardt, T. and Holtgrewe, M. and Gärtner, A. and Berger, F. and Beule, D. and Milting, H. and Schubert, S. and Klaassen, S. and Kühnisch, J.
Journal of Cardiovascular Development and Disease 9 (7): 216. 5 July 2022

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić, S. and Prada-Medina, C.A. and Landoulsi, Z. and Ghelfi, J. and Delcambre, S. and Dietrich, C. and Jarazo, J. and Henck, J. and Balachandran, S. and Pachchek, S. and Morris, C.M. and Antony, P. and Timmermann, B. and Sauer, S. and Pereira, S.L. and Schwamborn, J.C. and May, P. and Grünewald, A. and Spielmann, M.
Brain 145 (3): 964-978. March 2022

Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
Specker, E. and Matthes, S. and Wesolowski, R. and Schütz, A. and Grohmann, M. and Alenina, N. and Pleimes, D. and Mallow, K. and Neuenschwander, M. and Gogolin, A. and Weise, M. and Pfeifer, J. and Ziebart, N. and Heinemann, U. and von Kries, J.P. and Nazaré, M. and Bader, M.
Journal of Medicinal Chemistry 65 (16): 11126-11149. 25 August 2022

Berlin Registry of Neuroimmunological entities (BERLimmun): protocol of a prospective observational study.
Sperber, P.S. and Brandt, A.U. and Zimmermann, H.G. and Bahr, L.S. and Chien, C. and Rekers, S. and Mähler, A. and Böttcher, C. and Asseyer, S. and Duchow, A.S. and Bellmann-Strobl, J. and Ruprecht, K. and Paul, F. and Schmitz-Hübsch, T.
BMC Neurology 22 (1): 479. 14 December 2022

Pan-claudin family interactome analysis reveals shared and specific interactions.
Suarez Artiles, L. and Breiderhoff, T. and Girardello, R. and Gonschior, H. and Rodius, S. and Lesur, A. and Reimer, U. and Ramberger, E. and Perez-Hernandez, D. and Müller, D. and Mertins, P. and Dittmar, G.
Cell Reports 41 (6): 111588. 8 November 2022

Birth order, caesarean section, or daycare attendance in relation to child- and adult-onset type 1 diabetes: results from the german national cohort.
Tanoey, J. and Baechle, C. and Brenner, H. and Deckert, A. and Fricke, J. and Günther, K. and Karch, A. and Keil, T. and Kluttig, A. and Leitzmann, M. and Mikolajczyk, R. and Obi, N. and Pischon, T. and Schikowski, T. and Schipf, S.M. and Schulze, M.B. and Sedlmeier, A. and Moreno Velásquez, I. and Weber, K.S. and Völzke, H. and Ahrens, W. and Gastell, S. and Holleczek, B. and Jöckel, K.H. and Katzke, V. and Lieb, W. and Michels, K.B. and Schmidt, B. and Teismann, H. and Becher, H.
International Journal of Environmental Research and Public Health 19 (17): 10880. 31 August 2022

Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.
Thomalla, D. and Beckmann, L. and Grimm, C. and Oliverio, M. and Meder, L. and Herling, C.D. and Nieper, P. and Feldmann, T. and Merkel, O. and Lorsy, E. and da Palma Guerreiro, A. and von Jan, J. and Kisis, I. and Wasserburger, E. and Claasen, J. and Faitschuk-Meyer, E. and Altmüller, J. and Nürnberg, P. and Yang, T.P. and Lienhard, M. and Herwig, R. and Kreuzer, K.A. and Pallasch, C.P. and Buettner, R. and Schäfer, S.C. and Hartley, J. and Abken, H. and Peifer, M. and Kashkar, H. and Knittel, G. and Eichhorst, B. and Ullrich, R.T. and Herling, M. and Reinhardt, H.C. and Hallek, M. and Schweiger, M.R. and Frenzel, L.P.
Blood 140 (20): 2113-2126. 17 November 2022

Precise CRISPR/Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells.
Tran, N.T. and Danner, E. and Li, X. and Graf, R. and Lebedin, M. and de la Rosa, K. and Kühn, R. and Rajewsky, K. and Chu, V.T.
Science Advances 8 (22): eabm9106. 3 June 2022

Unraveling structural rearrangements of the CFH gene cluster in atypical hemolytic uremic syndrome patients using molecular combing and long-fragment targeted sequencing.
Tschernoster, N. and Erger, F. and Walsh, P.R. and McNicholas, B. and Fistrek, M. and Habbig, S. and Schumacher, L. and Folz-Donahue, K. and Kukat, C. and Toliat, M.R. and Becker, C. and Thiele, H. and Kavanagh, D. and Nürnberg, P. and Beck, B. and Altmüller, J.
Journal of Molecular Diagnostics 24 (6): 619-631. June 2022

TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation.
Tufan, A.B. and Lazarow, K. and Kolesnichenko, M. and Sporbert, A. and von Kries, J.P. and Scheidereit, C.
EMBO Journal 41 (21): e110372. 2 November 2022

Transcriptome analysis reveals putative genes involved in the lipid metabolism of chaulmoogra oil biosynthesis in Carpotroche brasiliensis (Raddi) A.Gray, a tropical tree species.
Vasconcelos, L.M. and Bittencourt, F. and Vidal, R.O. and Silva, E.M.A. and Costa, E.A. and Micheli, F. and Kirst, M. and Pirovani, C.P. and Gaiotto, F.A
Forests 13 (11): 1806. 29 October 2022

NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition.
Vesting, A.J. and Jais, A. and Klemm, P. and Steuernagel, L. and Wienand, P. and Fog-Tonnesen, M. and Hvid, H. and Schumacher, A.L. and Kukat, C. and Nolte, H. and Georgomanolis, T. and Altmüller, J. and Pasparakis, M. and Schmidt, A. and Krüger, M. and Supprian, M.S. and Waisman, A. and Straub, B.K. and Raschzok, N. and Bernier, M. and Birkenfeld, A.L. and Hövelmeyer, N. and Brüning, J.C. and Wunderlich, F.T.
Molecular Metabolism 66 : 101626. December 2022

Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H. and Dauksaite, V. and Sporbert, A. and Gotthardt, M. and Selbach, M.
Molecular Cell 82 (11): 2069-2083. 2 June 2022

Disruptors of AKAP-dependent protein-protein interactions.
Walker-Gray, R. and Pallien, T. and Miller, D.C. and Oder, A. and Neuenschwander, M. and von Kries, J.P. and Diecke, S. and Klussmann, E.
Methods in Molecular Biology 2483 : 117-139. 2022

Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay.
Wallmeroth, D. and Lackmann, J.W. and Kueckelmann, S. and Altmüller, J. and Dieterich, C. and Boehm, V. and Gehring, N.H.
EMBO Journal 41 (10): e109191. 16 May 2022

Venn diagrams may indicate erroneous statistical reasoning in transcriptomics.
Weiner, J. and Obermayer, B. and Beule, D.
Frontiers in Genetics 13 : 818683. 14 April 2022

Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma.
Welters, C. and Lammoglia Cobo, M.F. and Stein, C.A. and Hsu, M.T. and Ben Hamza, A. and Penter, L. and Chen, X. and Buccitelli, C. and Popp, O. and Mertins, P. and Dietze, K. and Bullinger, L. and Moosmann, A. and Blanc, E. and Beule, D. and Gerbitz, A. and Strobel, J. and Hackstein, H. and Rahn, H.P. and Dornmair, K. and Blankenstein, T. and Hansmann, L.
Cancer Immunology Research 10 (11): 1407-1419. 1 November 2022

Can fractal dimensions objectivize gastropod shell morphometrics? A case study from Lake Lugu (SW China).
Wiese, R. and Harrington, K. and Hartmann, K. and Hethke, M. and Rintelen, T. and Zhang, H. and Zhang, L.J. and Riedel, F.
Ecology and Evolution 12 (3): e8622. February 2022

EBAG9-silencing exerts an immune checkpoint function without aggravating adverse effects.
Wirges, A. and Bunse, M. and Joedicke, J.J. and Blanc, E. and Gudipati, V. and Moles, M.W. and Shiku, H. and Beule, D. and Huppa, J.B. and Höpken, U.E. and Rehm, A.
Molecular Therapy 30 (11): 3358-3378. 2 November 2022

Mutations in TAF8 cause a neurodegenerative disorder.
Wong, K.M. and Jepsen, W.M. and Efthymiou, S. and Salpietro, V. and Sanchez-Castillo, M. and Yip, J. and Kriouile, Y. and Diegmann, S. and Dreha-Kulaczewski, S. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Toosi, M.B. and Akhondian, J. and Ghayoor Karimiani, E. and Hummel-Abmeier, H. and Huppke, B. and Houlden, H. and Gärtner, J. and Maroofian, R. and Huppke, P.
Brain 145 (9): 3022-3034. September 2022

The transcription factor EB (TFEB) sensitizes the heart to chronic pressure overload.
Wundersitz, S. and Pablo Tortola, C. and Schmidt, S. and Oliveira Vidal, R. and Kny, M. and Hahn, A. and Zanders, L. and Katus, H.A. and Sauer, S. and Butter, C. and Luft, F.C. and Müller, O.J. and Fielitz, J.
International Journal of Molecular Sciences 23 (11): 5943. 25 May 2022

Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state.
Yigit, G. and Sheffer, R. and Daana, M. and Li, Y. and Kaygusuz, E. and Mor-Shakad, H. and Altmüller, J. and Nürnberg, P. and Douiev, L. and Kaulfuss, S. and Burfeind, P. and Wollnik, B. and Brockmann, K.
Journal of Medical Genetics 59 (6): 549-553. 20 May 2022

A preclinical study on brugada syndrome with a CACNB2 variant using human cardiomyocytes from induced pluripotent stem cells.
Zhong, R. and Schimanski, T. and Zhang, F. and Lan, H. and Hohn, A. and Xu, Q. and Huang, M. and Liao, Z. and Qiao, L. and Yang, Z. and Li, Y. and Zhao, Z. and Li, X. and Rose, L. and Albers, S. and Maywald, L. and Müller, J. and Dinkel, H. and Saguner, A. and Janssen, J.W.G. and Telugu, N.S. and Xi, Y. and Lang, S. and Kleinsorge, M. and Duru, F. and Zhou, X. and Diecke, S. and Cyganek, L. and Akin, I. and El-Battrawy, I.
International Journal of Molecular Sciences 23 (15): 8313. 1 August 2022

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U. and Milek, M. and Minia, I. and Vieira-Vieira, C.H. and Müller, S. and Mastrobuoni, G. and Hazapis, O.G. and Del Giudice, S. and Schwefel, D. and Bley, N. and Voigt, F. and Chao, J.A. and Kempa, S. and Hüttelmaier, S. and Selbach, M. and Landthaler, M.
Nature Communications 13 (1): 2727. 18 May 2022

Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling law.
Zou, X. and Schaefke, B. and Li, Y. and Jia, F. and Sun, W. and Li, G. and Liang, W. and Reif, T. and Heyd, F. and Gao, Q. and Tian, S. and Li, Y. and Tang, Y. and Fang, L. and Hu, Y. and Chen, W.
Life Science Alliance 5 (4): e202101333. April 2022

Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros.
Zywitza, V. and Frahm, S. and Krüger, N. and Weise, A. and Göritz, F. and Hermes, R. and Holtze, S. and Colleoni, S. and Galli, C. and Drukker, M. and Hildebrandt, T.B. and Diecke, S.
iScience 25 (11): 105414. 18 November 2022

Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction.
Zywitza, V. and Rusha, E. and Shaposhnikov, D. and Ruiz-Orera, J. and Telugu, N. and Rishko, V. and Hayashi, M. and Michel, G. and Wittler, L. and Stejskal, J. and Holtze, S. and Göritz, F. and Hermes, R. and Wang, J. and Izsvák, Z. and Colleoni, S. and Lazzari, G. and Galli, C. and Hildebrandt, T.B. and Hayashi, K. and Diecke, S. and Drukker, M.
Scientific Reports 12 (1): 3100. 8 March 2022

Therapeutic targets for phenolic compounds from agro-industrial by-products against obesity.
de la Luz Cádiz-Gurrea, M. and Fernández-Ochoa, Á. and Del Carmen Villegas-Aguilar, M. and Arráez-Román, D. and Segura-Carretero, A.
Current Medicinal Chemistry 29 (6): 1083-1098. 1 February 2022

2021

Mapping the human genetic architecture of COVID-19.

Nature 600 (7889): 472-477. December 2021

Preclinical MRI of the kidney : methods and protocols.
Pohlmann, A. and Niendorf, T., eds.
Methods in Molecular Biology, 2216 . Springer / Humana Press, New York, NY. ISBN 978-1-0716-0977-4 2021

Feasibility of a culturally adapted dietary weight-loss intervention among Ghanaian migrants in Berlin, Germany: the ADAPT study.
Amoah, S. and Ennin, R. and Sagoe, K. and Steinbrecher, A. and Pischon, T. and Mockenhaupt, F.P. and Danquah, I.
International Journal of Environmental Research and Public Health 18 (2): 510. 9 January 2021

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C. and Acemel, R.D. and Jedamzick, J. and Bolondi, A. and Cova, G. and Brieske, N. and Kuehn, R. and Wittler, L. and Real, F.M. and Lupianez, D.G.
bioRxiv : 2021.04.14.439779. 14 April 2021

Putative mobilized colistin resistance genes in the human gut microbiome.
Andrade, B.G.N. and Goris, T. and Afli, H. and Coutinho, F.H. and Dávila, A.M.R. and Cuadrat, R.R.C.
BMC Microbiology 21 : 220. 22 July 2021

PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel, L.M. and Franke, V. and Bruno, M. and Grishkovskaya, I. and Kasiliauskaite, A. and Kaufmann, T. and Schoeberl, U.E. and Puchinger, M.G. and Kostrhon, S. and Ebenwaldner, C. and Sebesta, M. and Beltzung, E. and Mechtler, K. and Lin, G. and Vlasova, A. and Leeb, M. and Pavri, R. and Stark, A. and Akalin, A. and Stefl, R. and Bernecky, C. and Djinovic-Carugo, K. and Slade, D.
Nature Communications 12 (1): 6078. 19 October 2021

Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect.
Arlt, B. and Mastrobuoni, G. and Wuenschel, J. and Astrahantseff, K. and Eggert, A. and Kempa, S. and Deubzer, H.E.
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1): 1282-1289. 30 June 2021

Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt, B. and Zasada, C. and Baum, K. and Wuenschel, J. and Mastrobuoni, G. and Lodrini, M. and Astrahantseff, K. and Winkler, A. and Schulte, J.H. and Finkler, S. and Forbes, M. and Hundsdoerfer, P. and Guergen, D. and Hoffmann, J. and Wolf, J. and Eggert, A. and Kempa, S. and Deubzer, H.E.
International Journal of Cancer 148 (5): 1219-1232. 1 March 2021

SNT: a unifying toolbox for quantification of neuronal anatomy.
Arshadi, C. and Günther, U. and Eddison, M. and Harrington, K.I.S. and Ferreira, T.A.
Nature Methods 18 : 374-377. April 2021

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Aschenbrenner, A.C. and Mouktaroudi, M. and Krämer, B. and Oestreich, M. and Antonakos, N. and Nuesch-Germano, M. and Gkizeli, K. and Bonaguro, L. and Reusch, N. and Baßler, K. and Saridaki, M. and Knoll, R. and Pecht, T. and Kapellos, T.S. and Doulou, S. and Kröger, C. and Herbert, M. and Holsten, L. and Horne, A. and Gemünd, I.D. and Rovina, N. and Agrawal, S. and Dahm, K. and van Uelft, M. and Drews, A. and Lenkeit, L. and Bruse, N. and Gerretsen, J. and Gierlich, J. and Becker, M. and Händler, K. and Kraut, M. and Theis, H. and Mengiste, S. and Domenico, E. and Schulte-Schrepping, J. and Seep, L. and Raabe, J. and Hoffmeister, C. and ToVinh, M. and Keitel, V. and Rieke, G. and Talevi, V. and Skowasch, D. and Aziz, N.A. and Pickkers, P. and van de Veerdonk, F.L. and Netea, M.G. and Schultze, J.L. and Kox, M. and Breteler, M.M.B. and Nattermann, J. and Koutsoukou, A. and Giamarellos-Bourboulis, E.J. and Ulas, T.
Genome Medicine 13 (1): 7. 13 January 2021

Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study.
Augustin, M. and Schommers, P. and Stecher, M. and Dewald, F. and Gieselmann, L. and Gruell, H. and Horn, C. and Vanshylla, K. and Cristanziano, V.D. and Osebold, L. and Roventa, M. and Riaz, T. and Tschernoster, N. and Altmueller, J. and Rose, L. and Salomon, S. and Priesner, V. and Luers, J.C. and Albus, C. and Rosenkranz, S. and Gathof, B. and Fätkenheuer, G. and Hallek, M. and Klein, F. and Suárez, I. and Lehmann, C.
The Lancet Regional Health - Europe 6 : 100122. July 2021

Assessing the (anti)-inflammatory potential of diets.
Bahr, L.S. and Franz, K. and Mähler, A.
Current Opinion in Clinical Nutrition and Metabolic Care 24 (5): 402-410. 1 September 2021

RS-FISH: Precise, interactive, fast, and scalable FISH spot detection.
Bahry, E. and Breimann, L. and Zouinkhi, M. and Epstein, L. and Kolyvanov, K. and Long, X. and Harrington, K.I.S. and Lionnet, T. and Preibisch, S.
bioRxiv : 2021.03.09.434205v2. 18 October 2021