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Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management

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Item Type:Review
Title:Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
Creators: Sinnecker, T., Kuchling, J. ORCID logoORCID: https://orcid.org/0000-0002-7981-2073, Dusek, P. ORCID logoORCID: https://orcid.org/0000-0003-4877-9642, Dörr, J., Niendorf, T. ORCID logoORCID: https://orcid.org/0000-0001-7584-6527, Paul, F. ORCID logoORCID: https://orcid.org/0000-0002-6378-0070 and Wuerfel, J. ORCID logoORCID: https://orcid.org/0000-0002-0034-8053
Abstract:Conventional magnetic resonance imaging (MRI) at 1.5 Tesla (T) is limited by modest spatial resolution and signal-to-noise ratio (SNR), impeding the identification and classification of inflammatory central nervous system changes in current clinical practice. Gaining from enhanced susceptibility effects and improved SNR, ultrahigh field MRI at 7 T depicts inflammatory brain lesions in great detail. This review summarises recent reports on 7 T MRI in neuroinflammatory diseases and addresses the question as to whether ultrahigh field MRI may eventually improve clinical decision-making and personalised disease management.
Keywords:7 Tesla, Ultrahigh field MRI, Multiple sclerosis, Neuromyelitis optica, Susac syndrome, Neuroimmunology, Central vein sign, Cortical lesions, Predictive, Preventive and Personalised Medicine
Source:EPMA Journal
ISSN:1878-5077
Publisher:BioMed Central
Volume:6
Number:1
Page Range:16
Date:27 August 2015
Official Publication:https://doi.org/10.1186/s13167-015-0038-y
PubMed:View item in PubMed

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