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Velocity oscillations in actin-based motility

Item Type:Article
Title:Velocity oscillations in actin-based motility
Creators Name:Gholami, A., Falcke, M. and Frey, E.
Abstract:We present a simple and generic theoretical description of actin-based motility, where polymerization of filaments maintains propulsion. The dynamics is driven by polymerization kinetics at the filaments' free ends, crosslinking of the actin network, attachment and detachment of filaments to the obstacle interface and entropic forces. We show that spontaneous oscillations in the velocity emerge due to a push-pull mechanism in a broad range of parameter values, and compare our findings with experiments.
Keywords:Listeria Monocytogenes, Polar Gels, Propulsion, Mechanism, Dynamics, Force, Polymerization, Growth, Chains
Source:New Journal of Physics
Publisher:IOP Publishing
Page Range:033022
Date:12 March 2008
Official Publication:https://doi.org/10.1088/1367-2630/10/3/033022

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