2012
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.
Guo, W and Schafer, S and Greaser, ML and Radke, MH and Liss, M and Govindarajan, T and Maatz, H and Schulz, H and Li, S and Parrish, AM and Dauksaite, V and Vakeel, P and Klaassen, S and Gerull, B and Thierfelder, L and Regitz-Zagrosek, V and Hacker, TA and Saupe, KW and Dec, GW and Ellinor, PT and Macrae, CA and Spallek, B and Fischer, R and Perrot, A and Ozcelik, C and Saar, K and Hubner, N and Gotthardt, M.
Nature Medicine 01 April 2012 (In Press)
Sortilin: a receptor to regulate neuronal viability and function.
Nykjaer, A and Willnow, TE.
Trends in Neurosciences 35 (4): 261-270. April 2012
The transcription factor c-Maf controls touch receptor development and function.
Wende, H and Lechner, SG and Cheret, C and Bourane, S and Kolanczyk, ME and Pattyn, A and Reuter, K and Munier, FL and Carroll, P and Lewin, GR and Birchmeier, C.
Science 335 (6074): 1373-1376. 16 March 2012
TAT-ARC protein transduction rescues mice from fulminant liver failure.
An, J and Harms, C and Laettig-Tuennemann, G and Sellge, G and Mandic, AD and Malato, Y and Heuser, A and Endres, M and Trautwein, C and Donath, S.
Hepatology 05 March 2012 (In Press)
The determinants of tumour immunogenicity.
Blankenstein, T and Coulie, PG and Gilboa, E and Jaffee, EM.
Nature Reviews Cancer 12 (4): 307-313. 01 March 2012
It takes two to tango: IkappaBs, the multifunctional partners of NF-kappaB.
Hinz, M and Coel Arslan, S and Scheidereit, C.
Immunological Reviews 246 (1): 59-76. March 2012
LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals.
Christ, A and Christa, A and Kur, E and Lioubinski, O and Bachmann, S and Willnow, TE and Hammes, A.
Developmental Cell 22 (2): 268-278. 14 February 2012
Rats, salt, and history.
Luft, FC.
Cell Metabolism 15 (2): 129-130. 08 February 2012
Targeting MET in cancer: rationale and progress.
Gherardi, E and Birchmeier, W and Birchmeier, C and Woude, GV.
Nature Reviews Cancer 12 (2): 89-103. 24 January 2012
Thalamic control of cortical states.
Poulet, JFA and Fernandez, LMJ and Crochet, S and Petersen, CCH.
Nature Neuroscience 15 (3): 370-372. 22 January 2012
Raising cytosolic Cl(-) in cerebellar granule cells affects their excitability and vestibulo-ocular learning.
Seja, P and Schonewille, M and Spitzmaul, G and Badura, A and Klein, I and Rudhard, Y and Wisden, W and Huebner, CA and De Zeeuw, CI and Jentsch, TJ.
EMBO Journal 31 (5): 1217-1230. 17 January 2012
Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease.
Schmidt, V and Baum, K and Lao, A and Rateitschak, K and Schmitz, Y and Teichmann, A and Wiesner, B and Petersen, CM and Nykjaer, A and Wolf, J and Wolkenhauer, O and Willnow, TE.
EMBO Journal 31 (1): 187-200. 04 January 2012
Small-molecule conversion of toxic oligomers to nontoxic {beta}-sheet-rich amyloid fibrils.
Bieschke, J and Herbst, M and Wiglenda, T and Friedrich, RP and Boeddrich, A and Schiele, F and Kleckers, D and Lopez Del Amo, JM and Gruening, BA and Wang, Q and Schmidt, MR and Lurz, R and Anwyl, R and Schnoegl, S and Faendrich, M and Frank, RF and Reif, B and Guenther, S and Walsh, DM and Wanker, EE.
Nature Chemical Biology 8 (1): 93-101. January 2012
2011
The molecular basis of acid insensitivity in the African naked mole-rat.
Smith, ES and Omerbasic, D and Lechner, SG and Anirudhan, G and Lapatsina, L and Lewin, GR.
Science 334 (6062): 1557-1560. 16 December 2011
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
von Eyss, B and Maaskola, J and Memczak, S and Moellmann, K and Schuetz, A and Loddenkemper, C and Tanh, MD and Otto, A and Muegge, K and Heinemann, U and Rajewsky, N and Ziebold, U.
EMBO Journal 31 (4): 972-985. 13 December 2011
Oncogene-targeting T cells reject large tumors while oncogene inactivation selects escape variants in mouse models of cancer.
Anders, K and Buschow, C and Herrmann, A and Milojkovic, A and Loddenkemper, C and Kammertoens, T and Daniel, P and Yu, H and Charo, J and Blankenstein, T.
Cancer Cell 20 (6): 755-767. 13 December 2011
In vivo and transcriptome-wide identification of RNA binding protein target sites.
Jungkamp, AC and Stoeckius, M and Mecenas, D and Gruen, D and Mastrobuoni, G and Kempa, S and Rajewsky, N.
Molecular Cell 44 (5): 828-840. 09 December 2011
KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man.
Heidenreich, M and Lechner, SG and Vardanyan, V and Wetzel, C and Cremers, CW and De Leenheer, EM and Aranguez, G and Moreno-Pelayo, MA and Jentsch, TJ and Lewin, GR.
Nature Neuroscience 15 (1): 138-145. 20 November 2011
Structure of Myxovirus resistance protein A reveals intra- and intermolecular domain interactions required for the antiviral function.
Gao, S and von der Malsburg, A and Dick, A and Faelber, K and Schroeder, GF and Haller, O and Kochs, G and Daumke, O.
Immunity 35 (4): 514-525. 28 October 2011
Opposing roles of NF-{kappa}B in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H and Kase, J and Doerr, JR and Milanovic, M and Lenze, D and Grau, M and Beuster, G and Ji, S and Reimann, M and Lenz, P and Hummel, M and Doerken, B and Lenz, G and Scheidereit, C and Schmitt, CA and Lee, S.
Genes & Development 25 (20): 2137-2146. 15 October 2011
BCL9-2 promotes early stages of intestinal tumor progression.
Brembeck, FH and Wiese, M and Zatula, N and Grigoryan, T and Dai, Y and Fritzmann, J and Birchmeier, W.
Gastroenterology 141 (4): 1359-1370. October 2011
Sleeping Beauty transposon mutagenesis in rat spermatogonial stem cells.
Ivics, Z and Izsvak, Z and Medrano, G and Chapman, KM and Hamra, FK.
Nature Protocols 6 (10): 1521-1535. October 2011
Crystal structure of nucleotide-free dynamin.
Faelber, K and Posor, Y and Gao, S and Held, M and Roske, Y and Schulze, D and Haucke, V and Noe, F and Daumke, O.
Nature 477 (7366): 556-560. 29 September 2011
Heart development: mitochondria in command of cardiomyocyte differentiation.
Drenckhahn, JD.
Developmental Cell 21 (3): 392-393. 13 September 2011
Macrophage development from hematopoietic stem cells requires PU.1 coordinated microRNA expression.
Ghani, S and Riemke, P and Schoenheit, J and Lenze, D and Stumm, J and Hoogenkamp, M and Lagendijk, A and Heinz, S and Bonifer, C and Bakkers, J and Abdelilah-Seyfried, S and Hummel, M and Rosenbauer, F.
Blood 118 (8): 2275-2284. 25 August 2011
Stem cells: Orphan receptors find a home.
Birchmeier, W.
Nature 476 (7360): 287-288. 18 August 2011
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.
Lebedeva, S and Jens, M and Theil, K and Schwanhaeusser, B and Selbach, M and Landthaler, M and Rajewsky, N.
Molecular Cell 43 (3): 340-352. 05 August 2011
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
Steininger, A and Moebs, M and Ullmann, R and Koechert, K and Kreher, S and Lamprecht, B and Anagnostopoulos, I and Hummel, M and Richter, J and Beyer, M and Janz, M and Klemke, CD and Stein, H and Doerken, B and Sterry, W and Schrock, E and Mathas, S and Assaf, C.
Journal of Experimental Medicine 208 (8): 1585-1593. 01 August 2011
Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs.
Rehm, A and Mensen, A and Schradi, K and Gerlach, K and Wittstock, S and Winter, S and Buechner, G and Doerken, B and Lipp, M and Hoepken, UE.
Blood 118 (4): 1020-1033. 28 July 2011
The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.
Popovic, J and Li, LP and Kloetzel, PM and Leisegang, M and Uckert, W and Blankenstein, T.
Blood 118 (4): 946-954. 28 July 2011
Novel effect of antihelminthic niclosamide on S100A4-mediated metastatic progression in colon cancer.
Sack, U and Walther, W and Scudiero, D and Selby, M and Kobelt, D and Lemm, M and Fichtner, I and Schlag, PM and Shoemaker, RH and Stein, U.
Journal of the National Cancer Institute 103 (13): 1018-1036. 06 July 2011
Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons.
Chiang, LY and Poole, K and Oliveira, BE and Duarte, N and Bernal Sierra, YA and Bruckner-Tuderman, L and Koch, M and Hu, J and Lewin, GR.
Nature Neuroscience 14 (8): 993-1000. 03 July 2011
De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics.
Adamidi, C and Wang, Y and Gruen, D and Mastrobuoni, G and You, X and Tolle, D and Dodt, M and Mackowiak, SD and Gogol-Doering, A and Oenal, P and Rybak, A and Ross, E and Alvarado, AS and Kempa, S and Dieterich, C and Rajewsky, N and Chen, W.
Genome Research 21 (7): 1193-1200. July 2011
ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity.
Leisle, L and Ludwig, CF and Wagner, FA and Jentsch, TJ and Stauber, T.
EMBO Journal 30 (11): 2140-2152. 01 June 2011
Ca(2+)-activated Cl(-) currents are dispensable for olfaction.
Billig, GM and Pal, B and Fidzinski, P and Jentsch, TJ.
Nature Neuroscience 14 (6): 763-769. June 2011
Global quantification of mammalian gene expression control.
Schwanhaeusser, B and Busse, D and Li, N and Dittmar, G and Schuchhardt, J and Wolf, J and Chen, W and Selbach, M.
Nature 473 (7347): 337-342. 19 May 2011
Aversion to nicotine is regulated by the balanced activity of beta4 and alpha5 nicotinic receptor subunits in the medial habenula.
Frahm, S and Slimak, MA and Ferrarese, L and Santos-Torres, J and Antolin-Fontes, B and Auer, S and Filkin, S and Pons, S and Fontaine, JF and Tsetlin, V and Maskos, U and Ibanez-Tallon, I.
Neuron 70 (3): 522-535. 12 May 2011
Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.
Gangadharan, V and Wang, R and Ulzhoefer, B and Luo, C and Bardoni, R and Bali, KK and Agarwal, N and Tegeder, I and Hildebrandt, U and Nagy, GG and Todd, AJ and Ghirri, A and Haeussler, A and Sprengel, R and Seeburg, PH and Macdermott, AB and Lewin, GR and Kuner, R.
Journal of Clinical Investigation 121 (4): 1608-1623. 01 April 2011
Physiology of microglia.
Kettenmann, H and Hanisch, UK and Noda, M and Verkhratsky, A.
Physiological Reviews 91 (2): 461-553. April 2011
Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells.
Leddin, M and Perrod, C and Hoogenkamp, M and Ghani, S and Assi, S and Heinz, S and Wilson, NK and Follows, G and Schoenheit, J and Vockentanz, L and Mosamam, A and Chen, W and Tenen, DG and Westhead, DR and Goettgens, B and Bonifer, C and Rosenbauer, F.
Blood 117 (10): 2827-2838. 10 March 2011
Re-dicing the pancreatic beta-cell: do microRNAs define cellular identity?
Tattikota, SG and Poy, MN.
EMBO Journal 30 (5): 797-799. 02 March 2011
A differential proteome screening system for post-translational modification-dependent transcription factor interactions.
Pless, O and Kowenz-Leutz, E and Dittmar, G and Leutz, A.
Nature Protocols 6 (3): 359-364. February 2011
The molecular and cellular identity of peripheral osmoreceptors.
Lechner, SG and Markworth, S and Poole, K and Smith, ES and Lapatsina, L and Frahm, S and May, M and Pischke, S and Suzuki, M and Ibanez-Tallon, I and Luft, FC and Jordan, J and Lewin, GR.
Neuron 69 (2): 332-344. 27 January 2011
2010
Neoadjuvant chemotherapy compared with surgery alone for locally advanced cancer of the stomach and cardia: European Organisation for Research and Treatment of Cancer Randomized Trial 40954.
Schuhmacher, C and Gretschel, S and Lordick, F and Reichardt, P and Hohenberger, W and Eisenberger, CF and Haag, C and Mauer, ME and Hasan, B and Welch, J and Ott, K and Hoelscher, A and Schneider, PM and Bechstein, W and Wilke, H and Lutz, MP and Nordlinger, B and Van Cutsem, E and Siewert, JR and Schlag, PM.
Journal of Clinical Oncology 28 (35): 5210-5218. 10 December 2010
Structure of a classical MHC class I molecule that binds "non-classical" ligands.
Hee, CS and Gao, S and Loll, B and Miller, MM and Uchanska-Ziegler, B and Daumke, O and Ziegler, A.
PLoS Biology 8 (12): e1000557. 07 December 2010
Divergent effects of central and peripheral renin on body weight and metabolism.
Luft, FC.
Cell Metabolism 12 (5): 423-424. 03 November 2010
MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors.
Leisegang, M and Wilde, S and Spranger, S and Milosevic, S and Frankenberger, B and Uckert, W and Schendel, DJ.
Journal of Clinical Investigation 120 (11): 3869-3877. 01 November 2010
Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.
Buchberger, A and Bukau, B and Sommer, T.
Molecular Cell 40 (2): 238-252. 22 October 2010
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation.
Hinz, M and Stilmann, M and Coel Arslan, S and Khanna, KK and Dittmar, G and Scheidereit, C.
Molecular Cell 40 (1): 63-74. 08 October 2010
ClC-3-A granular anion transporter involved in insulin secretion?
Jentsch, TJ and Maritzen, T and Keating, DJ and Zdebik, AA and Thevenod, F.
Cell Metabolism 12 (4): 307-308. 06 October 2010
In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis.
Siffrin, V and Radbruch, H and Glumm, R and Niesner, R and Paterka, M and Herz, J and Leuenberger, T and Lehmann, SM and Luenstedt, S and Rinnenthal, JL and Laube, G and Luche, H and Lehnardt, S and Fehling, HJ and Griesbeck, O and Zipp, F.
Immunity 33 (3): 424-436. 24 September 2010
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
Heinig, M and Petretto, E and Wallace, C and Bottolo, L and Rotival, M and Lu, H and Li, Y and Sarwar, R and Langley, SR and Bauerfeind, A and Hummel, O and Lee, YA and Paskas, S and Rintisch, C and Saar, K and Cooper, J and Buchan, R and Gray, EE and Cyster, JG and Braund, P and Gracey, J and Krishnan, U and Moore, JS and Nelson, CP and Pollard, H and Attwood, T and Crisp-Hihn, A and Foad, N and Jolley, J and Lloyd-Jones, H and Muir, D and Murray, E and O'Leary, K and Rankin, A and Sambrook, J and Godfroy, T and Brocheton, J and Proust, C and Schmitz, G and Heimerl, S and Lugauer, I and Belz, S and Gulde, S and Linsel-Nitschke, P and Sager, H and Schroeder, L and Lundmark, P and Syvannen, AC and Neudert, J and Scholz, M and Deloukas, P and Gray, E and Gwilliams, R and Niblett, D and Erdmann, J and Hengstenberg, C and Maouche, S and Ouwehand, WH and Rice, CM and Samani, NJ and Schunkert, H and Goodall, AH and Schulz, H and Roider, HG and Vingron, M and Blankenberg, S and Muenzel, T and Zeller, T and Szymczak, S and Ziegler, A and Tiret, L and Smyth, DJ and Pravenec, M and Aitman, TJ and Cambien, F and Clayton, D and Todd, JA and Huebner, N and Cook, SA.
Nature 467 (7314): 460-464. 23 September 2010
Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export.
Kjolby, M and Andersen, OM and Breiderhoff, T and Fjorback, AW and Pedersen, KM and Madsen, P and Jansen, P and Heeren, J and Willnow, TE and Nykjaer, A.
Cell Metabolism 12 (3): 213-223. 08 September 2010
Transgenic mice with a diverse human T cell antigen receptor repertoire.
Li, LP and Lampert, JC and Chen, X and Leitao, C and Popovic, J and Mueller, W and Blankenstein, T.
Nature Medicine 16 (9): 1029-1034. September 2010
MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain.
Somel, M and Guo, S and Fu, N and Yan, Z and Hu, HY and Xu, Y and Yuan, Y and Ning, Z and Hu, Y and Menzel, C and Hu, H and Lachmann, M and Zeng, R and Chen, W and Khaitovich, P.
Genome Research 20 (9): 1207-1218. September 2010
Chaperones get RISC loaded.
Landthaler, M.
Molecular Cell 39 (2): 161-162. 30 July 2010
Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis.
Novarino, G and Weinert, S and Rickheit, G and Jentsch, TJ.
Science 328 (5984): 1398-1401. 11 June 2010
Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulation.
Weinert, S and Jabs, S and Supanchart, C and Schweizer, M and Gimber, N and Richter, M and Rademann, J and Stauber, T and Kornak, U and Jentsch, TJ.
Science 328 (5984): 1401-1403. 11 June 2010
Generating knockout rats by transposon mutagenesis in spermatogonial stem cells.
Izsvak, Z and Froehlich, J and Grabundzija, I and Shirley, JR and Powell, HM and Chapman, KM and Ivics, Z and Hamra, FK.
Nature Methods 7 (6): 443-445. June 2010
Proteogenomics of Pristionchus pacificus reveals distinct proteome structure of nematode models.
Borchert, N and Dieterich, C and Krug, K and Schuetz, W and Jung, S and Nordheim, A and Sommer, RJ and Macek, B.
Genome Research 20 (6): 837-486. June 2010
Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao, S and von der Malsburg, A and Paeschke, S and Behlke, J and Haller, O and Kochs, G and Daumke, O.
Nature 465 (7297): 502-506. 27 May 2010
Ontologies in quantitative biology: a basis for comparison, integration, and discovery.
Jensen, LJ and Bork, P.
PLoS Biology 8 (5): e1000374. 25 May 2010
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Lamprecht, B and Walter, K and Kreher, S and Kumar, R and Hummel, M and Lenze, D and Koechert, K and Bouhlel, MA and Richter, J and Soler, E and Stadhouders, R and Joehrens, K and Wurster, KD and Callen, DF and Harte, MF and Giefing, M and Barlow, R and Stein, H and Anagnostopoulos, I and Janz, M and Cockerill, PN and Siebert, R and Doerken, B and Bonifer, C and Mathas, S.
Nature Medicine 16 (5): 571-579, 1p following 579. May 2010
Multiple sclerosis - candidate mechanisms underlying CNS atrophy.
Siffrin, V and Vogt, J and Radbruch, H and Nitsch, R and Zipp, F.
Trends in Neurosciences 33 (4): 202-210. April 2010
Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.
Kowenz-Leutz, E and Pless, O and Dittmar, G and Knoblich, M and Leutz, A.
EMBO Journal 29 (6): 1105-1115. 17 March 2010
Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Reimann, M and Lee, S and Loddenkemper, C and Doerr, JR and Tabor, V and Aichele, P and Stein, H and Doerken, B and Jenuwein, T and Schmitt, CA.
Cancer Cell 17 (3): 262-272. 16 March 2010
Silencing neurotransmission with membrane-tethered toxins.
Auer, S and Stuerzebecher, AS and Juettner, R and Santos-Torres, J and Hanack, C and Frahm, S and Liehl, B and Ibanez-Tallon, I.
Nature Methods 7 (3): 229-236. March 2010
Evidence for a protein tether involved in somatic touch.
Hu, J and Chiang, LY and Koch, M and Lewin, GR.
EMBO Journal 29 (4): 855-867. 17 February 2010
Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon their potential impact for early risk assessment in asymptomatic Chagas' patients.
Wallukat, G and Munoz Saravia, SG and Haberland, A and Bartel, S and Araujo, R and Valda, G and Duchen, D and Diaz Ramirez, I and Borges, AC and Schimke, I.
Journal of the American College of Cardiology 55 (5): 463-468. 02 February 2010
Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease.
Joutel, A and Monet-Lepretre, M and Gosele, C and Baron-Menguy, C and Hammes, A and Schmidt, S and Lemaire-Carrette, B and Domenga, V and Schedl, A and Lacombe, P and Huebner, N.
Journal of Clinical Investigation 120 (2): 433-445. 01 February 2010
C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
Wethmar, K and Begay, V and Smink, JJ and Zaragoza, K and Wiesenthal, V and Doerken, B and Calkhoven, CF and Leutz, A.
Genes & Development 24 (1): 15-20. 01 January 2010
A novel active endogenous retrovirus family contributes to genome variability in rat inbred strains.
Wang, Y and Liska, F and Gosele, C and Sedova, L and Kren, V and Krenova, D and Ivics, Z and Huebner, N and Izsvak, Z.
Genome Research 20 (1): 19-27. January 2010
No evidence for a role of CLCN2 variants in idiopathic generalized epilepsy.
Niemeyer, MI and Cid, LP and Sepulveda, FV and Blanz, J and Auberson, M and Jentsch, TJ.
Nature Genetics 42 (1): 3. January 2010
Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy.
Bader, M.
Annual Review of Pharmacology and Toxicology 50 : 439-65. 2010
2009
Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, SC and Hanna, J and Hirsch, C and Volkwein, C and Schuetz, A and Heinemann, U and Sommer, T and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009
The dangers of transcription.
Mathas, S and Misteli, T.
Cell 139 (6): 1047-1049. 11 December 2009
Quantitative proteomics: a tool to assess cell differentiation.
Vermeulen, M and Selbach, M.
Current Opinion in Cell Biology 21 (6): 761-766. December 2009
A fresh breeze from the ivory tower.
Birchmeier, C.
Current Opinion in Cell Biology 21 (6): 725-726. December 2009
A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation.
Stilmann, M and Hinz, M and Coel Arslan, S and Zimmer, A and Schreiber, V and Scheidereit, C.
Molecular Cell 36 (3): 365-378. 13 November 2009
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
Broeske, AM and Vockentanz, L and Kharazi, S and Huska, MR and Mancini, E and Scheller, M and Kuhl, C and Enns, A and Prinz, M and Jaenisch, R and Nerlov, C and Leutz, A and Andrade-Navarro, MA and Jacobsen, SE and Rosenbauer, F.
Nature Genetics 41 (11): 1207-1215. November 2009
Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression.
Stoeckius, M and Maaskola, J and Colombo, T and Rahn, HP and Friedlaender, MR and Li, N and Chen, W and Piano, F and Rajewsky, N.
Nature Methods 6 (10): 745-751. October 2009
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis.
Roepke, TK and King, EC and Reyna-Neyra, A and Paroder, M and Purtell, K and Koba, W and Fine, E and Lerner, DJ and Carrasco, N and Abbott, GW.
Nature Medicine 15 (10): 1186-1194. October 2009
Mitochondrial vesicles: an ancient process providing new links to peroxisomes.
Andrade-Navarro, MA and Sanchez-Pulido, L and McBride, HM.
Current Opinion in Cell Biology 21 (4): 560-567. August 2009
The tumor-associated antigen EBAG9 negatively regulates the cytolytic capacity of mouse CD8+ T cells.
Rueder, C and Hoepken, UE and Wolf, J and Mittruecker, HW and Engels, B and Erdmann, B and Wollenzin, S and Uckert, W and Doerken, B and Rehm, A.
Journal of Clinical Investigation 119 (8): 2184-2203. August 2009
Heat-responsive gene expression for gene therapy.
Walther, W and Stein, U.
Advanced Drug Delivery Reviews 61 (7-8): 641-649. 02 July 2009
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J and Morkel, M and Besser, D and Budczies, J and Kosel, F and Brembeck, FH and Stein, U and Fichtner, I and Schlag, PM and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system.
Schulze-Topphoff, U and Prat, A and Prozorovski, T and Siffrin, V and Paterka, M and Herz, J and Bendix, I and Ifergan, I and Schadock, I and Mori, MA and Van Horssen, J and Schroeter, F and Smorodchenko, A and Han, MH and Bader, M and Steinman, L and Aktas, O and Zipp, F.
Nature Medicine 15 (7): 788-793. July 2009
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction.
Zhang, Y and Tomann, P and Andl, T and Gallant, NM and Huelsken, J and Jerchow, B and Birchmeier, W and Paus, R and Piccolo, S and Mikkola, ML and Morrisey, EE and Overbeek, PA and Scheidereit, C and Millar, SE and Schmidt-Ullrich, R.
Developmental Cell 17 (1): 49-61. July 2009
Regulatory T cells ameliorate angiotensin II-induced cardiac damage.
Kvakan, H and Kleinewietfeld, M and Qadri, F and Park, JK and Fischer, R and Schwarz, I and Rahn, HP and Plehm, R and Wellner, M and Elitok, S and Gratze, P and Dechend, R and Luft, FC and Mueller, DN.
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Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates.
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A common variant on chromosome 11q13 is associated with atopic dermatitis.
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Nature Genetics 41 (5): 596-601. May 2009
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Cardiac deletion of the coxsackievirus-adenovirus receptor abolishes coxsackievirus b3 infection and prevents myocarditis in vivo.
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The ubiquitylation machinery of the endoplasmic reticulum.
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BK channels in innate immune functions of neutrophils and macrophages.
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MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
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Neuroglia: the 150 years after.
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Nature Medicine 14 (11): 1187-1188. November 2008
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Blood 112 (8): 3339-3347. 15 October 2008
Compensatory growth of healthy cardiac cells in the presence of diseased cells restores tissue homeostasis during heart development.
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The tight junction protein CAR regulates cardiac conduction and cell-cell communication.
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Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
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Mutations in sarcomere protein genes in left ventricular noncompaction.
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EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers.
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Nature Structural & Molecular Biology 15 (6): 558-566. June 2008
Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
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Wnt signalling and its impact on development and cancer.
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Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
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Nature Genetics 40 (5): 529-537. May 2008
SNP and haplotype mapping for genetic analysis in the rat.
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Nature Genetics 40 (5): 560-566. 28 April 2008
The salvaged area at risk in reperfused acute myocardial infarction as visualized by cardiovascular magnetic resonance.
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Journal of the American College of Cardiology 51 (16): 1581-1587. 22 April 2008
Sirt1 contributes critically to the redox-dependent fate of neural progenitors.
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Nature Cell Biology 10 (4): 385-394. April 2008
The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for?
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Trends in Neurosciences 31 (4): 163-169. April 2008
Discovering microRNAs from deep sequencing data using miRDeep.
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Nature Biotechnology 26 (4): 407-415. April 2008
Treatment-resistant chronic headaches and focal pachymeningitis in a 46-year-old man: a rare presentation of Wegener's granulomatosis.
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Lancet Neurology 7 (4): 368-372. April 2008
Subacute coronary stent thrombosis in cancer patients.
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Journal of the American College of Cardiology 51 (12): 1232-1233. 25 March 2008
Hydrolysis of extracellular ATP by CD39+ Treg cells: context matters!
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Blood 111 (2): 965-966. 15 January 2008
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PLoS Biology 6 (1): e13. January 2008
Lectins in the endoplasmic reticulum: the sweet side of protein quality control.
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Developmental Cell 14 (4): 463-464. 2008
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Nociceptive tuning by stem cell factor/c-Kit signaling.
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Neuron 56 (5): 893-906. 06 December 2007
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The adaptive immune response to sporadic cancer.
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Normal brain development in importin-alpha5 deficient-mice.
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FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.
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Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury.
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Microglia : active sensor and versatile effector cells in the normal and pathologic brain.
Hanisch, UK and Kettenmann, H.
Nature Neuroscience 10 (11): 1387-1394. November 2007
The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
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Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
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Nature 449 (7164): 923-927. 03 October 2007
Association and linkage of allelic variants of the dopamine transporter gene in ADHD.
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Neurotransmitter receptors on microglia.
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Trends in Neurosciences 30 (10): 527-535. October 2007
Mutations in the gene encoding the 3-5 DNA exonuclease TREX1 are associated with systemic lupus erythematosus.
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Nature Genetics 39 (9): 1065-1067. September 2007
Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis.
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PLoS Biology 5 (9): 1952-1961. September 2007
NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils.
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Neuroscience: The brain's garbage men.
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Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica.
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PLoS Medicine 4 (4): e133. April 2007
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CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity.
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STAT3 and MAPK signaling maintains overexpression of the heat shock proteins 90a and b in multiple myeloma cells, which critically contribute to tumor cell survival.
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A stomatin-domain protein essential for touch sensation in the mouse.
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2006
They are not too excited: the possible role of adult-born neurons in epilepsy.
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Neuron 52 (6): 935-937. 21 December 2006
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Triggering the brain's pathology sensor.
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Nature Neuroscience 9 : 1463-1464. 01 December 2006
Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy.
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Lipoprotein receptors in Alzheimer's disease.
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Coping with stress: cellular relaxation techniques.
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The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer.
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Co-evolution of transcriptional and post-translational cell-cycle regulation.
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Nature 443 : 594-597. 05 October 2006
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
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Nature Immunology 7 (10): 1037-1047. October 2006
Hungary's 'reforms' are threatening basic science.
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Building functional modules from molecular interactions.
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Trends in Biochemical Sciences 31 : 497-508. 01 September 2006
The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
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L(ou)sy miRNA targets?
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The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases.
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Reply to "Normalization procedures and detection of linkage signal in genetical-genomics experiments".
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A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
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Nature Cell Biology 8 (8): 849-854. August 2006
Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.
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Molecular Cell 23 (1): 13-23. 07 July 2006
Chromosomal rearrangements involving the BCL3 locus are recurrent in classical Hodgkin and peripheral T-cell lymphoma.
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Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism.
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M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere.
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The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment.
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An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
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Classical Hodgkin lymphoma is characterized by high constitutive expression of activating transcription factor 3 (ATF3) which promotes viability of Hodgkin/Reed-Sternberg cells.
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Toward automatic reconstruction of a highly resolved tree of life.
Ciccarelli, FD and Doerks, T and von Mehring, C and Creevey, CJ and Snel, B and Bork, P.
Science 311 (5765): 1283-1287. 03 March 2006
Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress.
Donath, S and Li, P and Willenbockel, C and Al-Saadi, N and Gross, V and Willnow, TE and Bader, M and Martin, U and Bauersachs, J and Wollert, KC and Dietz, R and von Harsdorf, R.
Circulation 113 : 1203-1212. 27 February 2006
Response: Cellular uptake of sex steroid hormones.
Willnow, TE and Nykjaer, A.
Cell 124 (3): 456-457. 10 February 2006
Literature mining for the biologist: from information retrieval to biological discovery.
Jensen, LJ and Saric, J and Bork, P.
Nature Reviews Genetics 7 : 119-129. 01 February 2006
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin.
Brembeck, FH and Rosario, M and Birchmeier, W.
Current Opinion in Genetics & Development 16 (1): 51-59. February 2006
Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.
Mathas, S and Janz, M and Hummel, F and Hummel, M and Wollert-Wulf, B and Lusatis, S and Anagnostopoulos, I and Lietz, A and Sigvardsson, M and Jundt, F and Joehrens, K and Bommert, K and Stein, H and Doerken, B.
Nature Immunology 7 (2): 207-215. February 2006
Expressing physiology.
Huebner, N.
Nature Genetics 38 (2): 140-141. February 2006
Apoptolidin: Induction of apoptosis by a natural product.
Daniel, PT and Koert, U and Schuppan, J.
Angewandte Chemie International Edition in English 45 : 872-893. 11 January 2006
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
Rosenbauer, F and Owens, BM and Yu, L and Tumang, JR and Steidl, U and Kutok, JL and Clayton, LK and Wagner, K and Scheller, M and Iwasaki, H and Liu, C and Hackanson, B and Akashi, K and Leutz, A and Rothstein, TL and Plass, C and Tenen, DG.
Nature Genetics 38 (1): 27-37. January 2006
2005
The effect of single-nucleotide polymorphism marker selection on patterns of haplotype blocks and haplotype frequency estimates.
Nothnagel, M and Rohde, K.
American Journal of Human Genetics 77 (6): 988-998. 01 December 2005
Plasma exchange for primary autoimmune autonomic failure.
Schroeder, C and Vernino, S and Birkenfeld, AL and Tank, J and Heusser, K and Lipp, A and Benter, T and Lindschau, C and Kettritz, R and Luft, FC and Jordan, J.
New England Journal of Medicine 353 : 1585-1590. 13 October 2005
Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domain.
Mo, X and Kowenz-Leutz, E and Laumonnier, Y and Xu, H and Leutz, A.
Genes & Development 19 : 2447-2457. 29 September 2005
A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl, U and Worm, U and Lalowski, M and Haenig, C and Brembeck, FH and Goehler, H and Stroedicke, M and Zenkner, M and Schoenherr, A and Koeppen, S and Timm, J and Mintzlaff, S and Abraham, C and Bock, N and Kietzmann, S and Goedde, A and Toksoez, E and Droege, A and Krobitsch, S and Korn, B and Birchmeier, W and Lehrach, H and Wanker, EE.
Cell 122 (6): 957-968. 23 September 2005
Ubx2 links the Cdc48 complex to ER-associated protein degradation.
Neuber, O and Jarosch, E and Volkwein, C and Walter, J and Sommer, T.
Nature Cell Biology 7 : 993-998. 18 September 2005
CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells.
Vasyutina, E and Stebler, J and Brand-Saberi, B and Schulz, S and Raz, E and Birchmeier, C.
Genes & Development 19 (18): 2187-2198. 15 September 2005
Role of endocytosis in cellular uptake of sex steroids.
Hammes, A and Andreassen, TK and Spoelgen, R and Raila, J and Huebner, N and Schulz, H and Metzger, J and Schweigert, FJ and Luppa, PB and Nykjaer, A and Willnow, TE.
Cell 122 : 751-762. 09 September 2005
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Andersen, OM and Reiche, J and Schmidt, V and Gotthardt, M and Spoelgen, R and Behlke, J and von Arnim, CAF and Breiderhoff, T and Jansen, P and Wu, X and Bales, KR and Cappai, R and Masters, CL and Gliemann, J and Mufson, EJ and Hyman, BT and Paul, SM and Nykjaer, A and Willnow, TE.
Proceedings of the National Academy of Sciences of the United States of America 102 : 13461-13466. 07 September 2005
Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance.
Willimsky, G and Blankenstein, T.
Nature 437 : 141-146. 01 September 2005
Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large cell, and other peripheral T-cell lymphomas.
Mathas, S and Joehrens, K and Joos, S and Lietz, A and Hummel, F and Janz, M and Jundt, F and Anagnostopoulos, I and Bommert, K and Lichter, P and Stein, H and Scheidereit, C and Doerken, B.
Blood 106 : 4287-4293. 25 August 2005
Non-genotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma.
Stuehmer, T and Chatterjee, M and Hildebrandt, M and Herrmann, P and Gollasch, H and Gerecke, C and Theurich, S and Cigliano, L and Manz, RA and Daniel, PT and Bommert, K and Vassilev, LT and Bargou, RC.
Blood 106 : 3609-3617. 04 August 2005
Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M and Lee, S and Loddenkemper, C and Rudolph, C and Peters, AH and Schlegelberger, B and Stein, H and Doerken, B and Jenuwein, T and Schmitt, CA.
Nature 436 (7051): 660-665. 04 August 2005
ERAD: the long road to destruction.
Meusser, B and Hirsch, C and Jarosch, E and Sommer, T.
Nature Cell Biology 7 (8): 766-772. August 2005
Recruitment of DNA methyltransferase I to DNA repair sites.
Mortusewicz, O and Schermelleh, L and Walter, J and Cardoso, MC and Leonhardt, H.
Proceedings of the National Academy of Sciences of the United States of America 102 (25): 8905-8909. 21 June 2005
Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation.
Brero, A and Easwaran, HP and Nowak, D and Grunewald, I and Cremer, T and Leonhardt, H and Cardoso, MC.
Journal of Cell Biology 169 (5): 733-743. 06 June 2005
Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity.
Juettner, R and More, MI and Das, D and Babich, A and Meier, J and Henning, M and Erdmann, B and Mueller, EC and Otto, A and Grantyn, R and Rathjen, FG.
Neuron 46 (2): 233-245. 21 May 2005
Urokinase-induced signaling in human vascular smooth muscle cells is mediated by PDGFR-beta.
Kiyan, J and Kiyan, R and Haller, H and Dumler, I.
EMBO Journal 24 : 1787-1797. 18 May 2005
Systematic association of genes to phenotypes by genome and literature mining.
Korbel, JO and Doerks, T and Jensen, LJ and Perez-Iratxeta, C and Kaczanowski, S and Hooper, SD and Andrade, MA and Bork, P.
PLoS Biology 3 (5): e134. 05 April 2005
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.
Huebner, N and Wallace, CA and Zimdahl, H and Petretto, E and Schulz, H and Maciver, F and Mueller, M and Hummel, O and Monti, J and Zidek, V and Musilova, A and Kren, V and Causton, H and Game, L and Born, G and Schmidt, S and Mueller, A and Cook, SA and Kurtz, TW and Whittaker, J and Pravenec, M and Aitman, TJ.
Nature Genetics 37 (3): 243-253. 01 March 2005
Dynamic complex formation during the yeast cell cycle.
de Lichtenberg, U and Jensen, LJ and Brunak, S and Bork, P.
Science 307 (5710): 724-727. 04 February 2005
Pardon me - No access without ubiquitin.
Sommer, T and Jarosch, E.
Developmental Cell 8 : 4-5. 01 January 2005
CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T cell subset.
Kleinewietfeld, M and Puentes, F and Borsellino, G and Battistini, L and Roetzschke, O and Falk, K.
Blood 105 : 2877-2886. 01 January 2005
Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization.
Turnbull, AP and Kuemmel, D and Prinz, B and Holz, C and Schultchen, J and Lang, C and Niesen, FH and Hofmann, KP and Delbrueck, H and Behlke, J and Mueller, EC and Jarosch, E and Sommer, T and Heinemann, U.
EMBO Journal 24 : 875-884. 01 January 2005
A whole lotta jumpin' goin' on: new transposon tools for vertebrate functional genomics.
Ivics, Z and Izsvak, Z.
Trends in Genetics 21 : 8-11. 01 January 2005
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection (authors reply inN Engl J Med. 2005 May 12;352(19):2027-8).
Dragun, D and Mueller, DN and Braesen, JH and Fritsche, L and Nieminen-Kelhae, M and Dechend, R and Kintscher, U and Rudolph, B and Hoebeke, J and Eckert, D and Mazak, I and Plehm, R and Schoenemann, C and Unger, T and Budde, K and Neumayer, HH and Luft, FC and Wallukat, G.
New England Journal of Medicine 352 : 558-569. 01 January 2005
Complex genomic rearrangements lead to novel primate gene function.
Ciccarelli, FD and von Mering, C and Suyama, M and Harrington, ED and Izaurralde, E and Bork, P.
Genome Research 15 : 343-351. 01 January 2005
The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord.
Mueller, T and Anlag, K and Wildner, H and Britsch, S and Treier, M and Birchmeier, C.
Genes & Development 19 : 733-743. 01 January 2005
San1p, checking up on nuclear proteins.
Sommer, T and Hirsch, C.
Cell 120 : 734-736. 01 January 2005
Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo.
Freund, C and Schmidt-Ullrich, R and Baurand, A and Dunger, S and Schneider, W and Loser, P and El-Jamali, A and Dietz, R and Scheidereit, C and Bergmann, MW.
Circulation 111 : 2319-2325. 01 January 2005
A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein beta and NF-kappaB activity in Hodgkin and anaplastic large cell lymphomas.
Jundt, F and Raetzel, N and Mueller, C and Calkhoven, CF and Kley, K and Mathas, S and Lietz, A and Leutz, A and Doerken, B.
Blood 106 : 1801-1807. 01 January 2005
Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.
Fiebeler, A and Nussberger, J and Shagdarsuren, E and Rong, S and Hilfenhaus, G and Al-Saadi, N and Dechend, R and Wellner, M and Meiners, S and Maser-Gluth, C and Jeng, AY and Webb, RL and Luft, FC and Mueller, DN.
Circulation 111 : 3087-3094. 01 January 2005
2004
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
Schuetz, G and Rosario, M and Grimm, J and Boeckers, TM and Gundelfinger, ED and Birchmeier, W.
Journal of Cell Biology 167 (5): 945-952. 06 December 2004
Paracrine role for periadventitial adipose tissue in the regulation of arterial tone.
Gollasch, M and Dubrovska, G.
Trends in Pharmacological Sciences 25 : 647-653. 01 December 2004
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy [Corrigendum in: Nat Genet. 2005 Jan;37(1):106].
Gerull, B and Heuser, A and Wichter, T and Paul, M and Basson, CT and McDermott, DA and Lerman, BB and Markowitz, SM and Ellinor, PT and MacRae, CA and Peters, S and Grossmann, KS and Drenckhahn, J and Michely, B and Sasse-Klaassen, S and Birchmeier, W and Dietz, R and Breithardt, G and Schulze-Bahr, E and Thierfelder, L.
Nature Genetics 36 : 1162-1164. 17 October 2004
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
Grossmann, KS and Grund, C and Huelsken, J and Behrend, M and Erdmann, B and Franke, WW and Birchmeier, W.
Journal of Cell Biology 167 (1): 149-160. 11 October 2004
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease [Erratum in: Mol Cell. vol 19, pg 287, 2005].
Goehler, H and Lalowski, M and Stelzl, U and Waelter, S and Stroedicke, M and Worm, U and Droege, A and Lindenberg, KS and Knoblich, M and Haenig, C and Herbst, M and Suopanki, J and Scherzinger, E and Abraham, C and Bauer, B and Hasenbank, R and Fritzsche, A and Ludewig, AH and Buessow, K and Coleman, SH and Gutekunst, CA and Landwehrmeyer, BG and Lehrach, H and Wanker, EE.
Molecular Cell 15 : 853-865. 24 September 2004
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Brembeck, FH and Schwarz-Romond, T and Bakkers, J and Wilhelm, S and Hammerschmidt, M and Birchmeier, W.
Genes & Development 18 : 2225-2230. 15 September 2004
Milestones of neuronal development in the adult hippocampus.
Kempermann, G and Jessberger, S and Steiner, B and Kronenberg, G.
Trends in Neurosciences 27 (8): 447-452. 01 August 2004
Mutations in the gene encoding gap junction protein alpha 12 (connexin 46.6) cause Pelizaeus-Merzbacher-like disease.
Uhlenberg, B and Schuelke, M and Rueschendorf, F and Ruf, N and Kaindl, AM and Henneke, M and Thiele, H and Stoltenburg-Didinger, G and Aksu, F and Topaloglu, H and Nuernberg, P and Huebner, C and Weschke, B and Gaertner, J.
American Journal of Human Genetics 75 (2): 251-260. August 2004
Analysis of genomic context: prediction of functional associations from conserved bidirectionally transcribed gene pairs.
Korbel, JO and Jensen, LJ and von Mering, C and Bork, P.
Nature Biotechnology 22 : 911-917. 01 July 2004
Making tubes: Step by step.
Rosario, M and Birchmeier, W.
Developmental Cell 7 : 3-5. 01 July 2004
Allelic heterogeneity in the COH1 gene explains clinical variability in Cohen syndrome.
Hennies, HC and Rauch, A and Seifert, W and Schumi, C and Moser, E and Al-Taji, E and Tariverdian, G and Chrzanowska, KH and Krajewska-Walasek, M and Rajab, A and Giugliani, R and Neumann, TE and Eckl, KM and Karbasiyan, M and Reis, A and Horn, D.
American Journal of Human Genetics 75 (1): 138-145. July 2004
Novel gene locus for autosomal dominant left ventricular noncompaction maps to chromosome 11p15.
Sasse-Klaassen, S and Probst, S and Gerull, B and Oechslin, E and Nuernberg, P and Heuser, A and Jenni, R and Hennies, HC and Thierfelder, L.
Circulation 109 : 2720-2723. 08 June 2004
Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells.
Mazak, I and Fiebeler, A and Muller, DN and Park, JK and Shagdarsuren, E and Lindschau, C and Dechend, R and Viedt, C and Pilz, B and Haller, H and Luft, FC.
Circulation 109 : 2792-2800. 08 June 2004
Water potentiates the pressor effect of ephedra alkaloids.
Jordan, J and Shannon, JR and Diedrich, A and Black, B and Robertson, D and Biaggioni, I.
Circulation 109 : 1823-1825. 20 April 2004
c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
Mathas, S and Lietz, A and Anagnostopoulos, I and Hummel, F and Wiesner, B and Janz, M and Jundt, F and Hirsch, B and Joehrens-Leder, K and Vornlocher, HP and Bommert, K and Stein, H and Doerken, B.
Journal of Experimental Medicine 199 (8): 1041-1052. 19 April 2004
All roads lead to rome: triggering dendritic cell migration.
Hoepken, UE and Lipp, M.
Immunity 20 : 244-246. 01 March 2004
A cancer immunosurveillance controversy.
Qin, ZH and Blankenstein, T.
Nature Immunology 5 : 3-4. 01 January 2004
Lymphoid organogenesis: getting the green light from RORgammat.
Lipp, M and Mueller, G.
Nature Immunology 5 : 12-14. 01 January 2004
A SNP map of the rat genome generated from cDNA sequences.
Zimdahl, H and Nyakatura, G and Brandt, P and Schulz, H and Hummel, O and Fartmann, B and Brett, D and Droege, M and Monti, J and Lee, YA and Sun, YY and Zhao, SY and Winter, EE and Ponting, CP and Chen, Y and Kasprzyk, A and Birney, E and Ganten, D and Huebner, N.
Science 303 : 807-807. 01 January 2004
Healing the wounds inflicted by Sleeping Beauty transposition by double-strand break repair in mammalian somatic cells.
Izsvak, Z and Stuewe, EE and Fiedler, D and Katzer, A and Jeggo, PA and Ivics, Z.
Molecular Cell 13 : 279-290. 01 January 2004
Ras induces mediator complex exchange on C/EBPbeta.
Mo, XM and Kowenz-Leutz, E and Xu, H and Leutz, A.
Molecular Cell 13 : 241-250. 01 January 2004
Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation.
Meusser, B and Sommer, T.
Molecular Cell 14 : 247-258. 01 January 2004
Global analysis of bacterial transcription factors to predict cellular target processes.
Doerks, T and Andrade, MA and Lathe, W and von Mering, C and Bork, P.
Trends in Genetics 20 : 126-131. 01 January 2004
Met provides essential signals for liver regeneration.
Borowiak, M and Garratt, AN and Wuestefeld, T and Strehle, M and Trautwein, C and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 101 : 10608-10613. 01 January 2004
Estimating rates of alternative splicing in mammals and invertebrates.
Harrington, ED and Boue, S and Valcarcel, J and Reich, JG and Bork, P.
Nature Genetics 36 : 916-917. 01 January 2004
Regenerative capacity of the myocardium: implications for treatment of heart failure.
von Harsdorf, R and Poole-Wilson, PA and Dietz, R.
Lancet 363 : 1306-1313. 01 January 2004
Cellular senescence in cancer treatment: friend or foe?
Kahlem, P and Doerken, B and Schmitt, CA.
Journal of Clinical Investigation 113 (2): 169-174. January 2004
2003
Met, metastasis, motility and more.
Birchmeier, C and Birchmeier, W and Gherardi, E and Vande Woude, GF.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003
Tumor rejection by modulation of tumor stromal fibroblasts.
Schueler, T and Koernig, S and Blankenstein, T.
Journal of Experimental Medicine 198 (10): 1487-1493. 17 November 2003
The hunt for huntingtin function: interaction partners tell many different stories.
Harjes, P and Wanker, EE.
Trends in Biochemical Sciences 28 (8): 425-433. August 2003
Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
Gillissen, B and Essmann, F and Graupner, V and Staerck, L and Radetzki, S and Doerken, B and Schulze-Osthoff, K and Daniel, PT.
EMBO Journal 22 : 3580-3590. 15 July 2003
Macrophage inflammatory protein 1-alpha (MIP-1alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.
Lentzsch, S and Gries, M and Janz, M and Bargou, R and Doerken, B and Mapara, MY.
Blood 101 : 3568-3573. 01 May 2003
Induction of tumors in mice by genomic hypomethylation.
Gaudet, F and Hodgson, JG and Eden, A and Jackson-Grusby, L and Dausman, J and Gray, JW and Leonhardt, H and Jaenisch, R.
Science 300 (5618): 489-492. 18 April 2003
Transcriptional profiling identifies Id2 function in dendritic cell development.
Hacker, C and Kirsch, RD and Ju, XS and Hieronymus, T and Gust, TC and Kuhl, C and Jorgas, T and Kurz, SM and Rose-John, S and Yokota, Y and Zenke, M.
Nature Immunology 4 (4): 380-386. April 2003
Synthesis of serotonin by a second tryptophan hydroxylase isoform.
Walther, DJ and Peter, JU and Bashammakh, S and Hoertnagl, H and Voits, M and Fink, H and Bader, M.
Science 299 : 76-76. 01 January 2003
Chemotherapy response and resistance.
Lee, S and Schmitt, CA.
Current Opinion in Genetics & Development 13 : 90-96. 01 January 2003
The role of IFN-gamma in tumor transplantation immunity and inhibition of chemical carcinogenesis.
Blankenstein, T and Qin, ZH.
Current Opinion in Immunology 15 : 148-154. 01 January 2003
Concerted action of the chemokine and lymphotoxin system in secondary lymphoid-organ development.
Mueller, G and Lipp, M.
Current Opinion in Immunology 15 : 217-224. 01 January 2003
Facilities and methods for the high-throughput crystal structural analysis of human proteins.
Heinemann, U and Buessow, K and Mueller, U and Umbach, P.
Accounts of Chemical Research 36 : 157-163. 01 January 2003
Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy.
Geier, C and Perrot, A and Ozcelik, C and Binner, P and Counsell, D and Hoffmann, K and Pilz, B and Martiniak, Y and Gehmlich, KA and van der Ven, PFM and Furst, DO and Vornwald, A and von Hodenberg, E and Nuernberg, P and Scheffold, T and Dietz, R and Osterziel, KJ.
Circulation 107 : 1390-1395. 01 January 2003
Translational control of SCL-isoform expression in hematopoietic lineage choice.
Calkhoven, CF and Mueller, C and Martin, R and Krosl, G and Hoang, T and Leutz, A.
Genes & Development 17 (8): 959-964. 01 January 2003
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase.
Dechend, R and Viedt, C and Mueller, DN and Ugele, B and Brandes, RP and Wallukat, G and Park, JK and Janke, J and Barta, P and Theuer, J and Fiebeler, A and Homuth, V and Dietz, R and Haller, H and Kreuzer, J and Luft, FC.
Circulation 107 (12): 1632-1639. 01 January 2003
Senescence apoptosis and therapy - cutting the lifelines of cancer.
Schmitt, CA.
Nature Reviews Cancer 3 (4): 286-295. 01 January 2003
Metabolites: a helping hand for pathway evolution?
Schmidt, S and Sunyaev, S and Bork, P and Dandekar, T.
Trends in Biochemical Sciences 28 : 336-341. 01 January 2003
Systematic discovery of analogous enzymes in thiamin biosynthesis.
Morett, E and Korbel, J and Rajan, E and Saab-Rincon, G and Olvera, L and Olvera, M and Steffen, S and Snel, B and Bork, P.
Nature Biotechnology 21 : 790-795. 01 January 2003
A T-type calcium channel required for normal function of a mammalian mechanoreceptor.
Shin, JB and Martinez-Salgado, C and Heppenstall, PA and Lewin, GR.
Nature Neuroscience 6 : 724-730. 01 January 2003
Selective impairment in sympathetic vasomotor control with norepinephrine transporter inhibition.
Tank, J and Schroeder, C and Diedrich, A and Szczech, E and Haertter, S and Sharma, AM and Luft, FC and Jordan, J.
Circulation 107 : 2949-2954. 01 January 2003
How to make tubes: signaling by the Met receptor tyrosine kinase.
Rosario, M and Birchmeier, W.
Trends in Cell Biology 13 : 328-335. 01 January 2003
Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification.
Rutsch, F and Ruf, N and Vaingankar, S and Toliat, MR and Suk, A and Hoehne, W and Schauer, G and Lehmann, M and Roscioli, T and Schnabel, D and Epplen, JT and Knisely, A and Superti-Furga, A and McGill, J and Filippone, M and Sinaiko, AR and Vallance, H and Hinrichs, B and Smith, W and Ferre, M and Terkeltaub, R and Nuernberg, P.
Nature Genetics 34 : 379-381. 01 January 2003
Inhibition of NF-kappa B essentially contributes to arsenic-induced apoptosis.
Mathas, S and Lietz, A and Janz, M and Hinz, M and Jundt, F and Scheidereit, C and Bommert, K and Doerken, B.
Blood 102 : 1028-1034. 01 January 2003
The KIND module: a putative signalling domain evolved from the C lobe of the protein kinase fold.
Ciccarelli, FD and Bork, P and Kerkhoff, E.
Trends in Biochemical Sciences 28 : 349-352. 01 January 2003
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Soshnikova, N and Zechner, D and Huelsken, J and Mishina, Y and Behringer, RR and Taketo, MM and Crenshaw, EB and Birchmeier, W.
Genes & Development 17 : 1963-1968. 01 January 2003
A splice mutation in a Syrian autosomal recessive hypercholesterolemia family causes a two-nucleotide deletion of mRNA.
Al Kateb, H and Bautz, EKF and Luft, FC and Baehring, S.
Circulation Research 93 : E49-E50. 01 January 2003
Dynamic expression profile of p21 WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy.
Rau, B and Sturm, I and Lage, H and Berger, S and Schneider, U and Haupfmann, S and Wust, P and Riess, H and Schlag, PM and Doerken, B and Daniel, PT.
Journal of Clinical Oncology 21 : 3391-3401. 01 January 2003
Neuroscience - Microglia: The enemy within?
Kempermann, G and Neumann, H.
Science 302 : 1689-1690. 01 January 2003
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release.
Walther, DJ and Peter, JU and Winter, S and Hoeltje, M and Paulmann, N and Grohmann, M and Vowinckel, J and Alamo-Bethencourt, V and Wilhelm, CS and Ahnert-Hilger, G and Bader, M.
Cell 115 : 851-862. 01 January 2003
Genome evolution reveals biochemical networks and functional modules.
von Mering, C and Zdobnov, EM and Tsoka, S and Ciccarelli, FD and Pereira-Leal, JB and Ouzounis, CA and Bork, P.
Proceedings of the National Academy of Sciences of the United States of America 100 : 15428-15433. 01 January 2003
Monocyte-expressed urokinase inhibits vascular smooth muscle cell growth by activating Stat1.
Kunigal, S and Kusch, A and Tkachuk, N and Tkachuk, S and Jerke, U and Haller, H and Dumler, I.
Blood 102 : 4377-4383. 01 January 2003
Blood oxygen level-dependent magnetic resonance imaging in patients with stress-induced angina.
Friedrich, MG and Niendorf, T and Schulz-Menger, J and Gross, CM and Dietz, R.
Circulation 108 (18): 2219-2223. 01 January 2003
Potential for sibutramine-yohimbine interaction? (correspondence).
Jordan, J and Sharma, AM.
Lancet 361 : 1826. 01 January 2003
2002
The final cut: how ERAP1 trims MHC ligands to size.
Falk, K and Roetzschke, O.
Nature Immunology 3 : 1121-1122. 01 December 2002
cGMP-mediated signaling via cGKI�s required for the guidance and connectivity of sensory axons.
Schmidt, H and Werner, M and Heppenstall, PA and Henning, M and More, MI and Kuehbandner, S and Lewin, GR and Hofmann, F and Feil, R and Rathjen, FG.
Journal of Cell Biology 159 (3): 489-498. 11 November 2002
Nucleolin as activator of human papillomavirus type 18 oncogene transcription in cervical cancer.
Grinstein, E and Wernet, P and Snijders, PJF and Rosl, F and Weinert, I and Jia, WT and Kraft, R and Schewe, C and Schwabe, M and Hauptmann, S and Dietel, M and Meijer, CJLM and Royer, HD.
Journal of Experimental Medicine 196 (8): 1067-1078. 21 October 2002
Nuclear factor [kappa]B-dependent gene expression profiling of Hodgkins disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.
Hinz, M and Lemke, P and Anagnostopoulos, I and Hacker, C and Krappmann, D and Mathas, S and Doerken, B and Zenke, M and Stein, H and Scheidereit, C.
Journal of Experimental Medicine 196 (5): 605-617. 02 September 2002
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.
Heiser, V and Engemann, S and Broecker, W and Dunkel, I and Boeddrich, A and Waelter, S and Nordhoff, E and Lurz, R and Schugardt, N and Rautenberg, S and Herhaus, C and Barnickel, G and Boettcher, H and Lehrach, H and Wanker, EE.
Proceedings of the National Academy of Sciences of the United States of America 99, Suppl. 4 : 16400-16406. 28 August 2002
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.
Mathas, S and Hinz, M and Anagnostopoulos, L and Krappmann, D and Lietz, A and Jundt, F and Bommert, K and Mechta-Grigoriou, F and Stein, H and Doerken, B and Scheidereit, C.
EMBO Journal 21 (15): 4104-4113. 01 August 2002
Inhibition of methylcholanthrene-induced carcinogenesis by an interferon gamma receptor-dependent foreign body reaction.
Qin, ZH and Kim, HJ and Hemme, J and Blankenstein, T.
Journal of Experimental Medicine 195 (11): 1479-1490. 03 June 2002
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy.
Schmitt, CA and Fridman, JS and Yang, M and Lee, S and Baranov, E and Hoffman, RM and Lowe, SW.
Cell 109 : 335-346. 03 May 2002
BSD: a novel domain in transcription factors and synapse-associated proteins.
Doerks, T and Huber, S and Buchner, E and Bork, P.
Trends in Biochemical Sciences 27 : 168-170. 01 April 2002
Baroreflex buffering and susceptibility to vasoactive drugs.
Jordan, J and Tank, J and Shannon, JR and Diedrich, A and Lipp, A and Schroeder, C and Arnold, G and Sharma, AM and Biaggioni, I and Robertson, D and Luft, FC.
Circulation 105 : 1459-1464. 26 March 2002
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.
Fujita, Y and Krause, G and Scheffner, M and Zechner, D and Leddy, HEM and Behrens, J and Sommer, T and Birchmeier, W.
Nature Cell Biology 4 (3): 222-231. 01 March 2002
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning.
Faendrich, F and Lin, X and Chai, GX and Schulze, M and Ganten, D and Bader, M and Holle, J and Huang, DS and Parwaresch, R and Zavazava, N and Binas, B.
Nature Medicine 8 : 171-178. 01 February 2002
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.
Jarosch, E and Taxis, C and Volkwein, C and Bordallo, J and Finley, D and Wolf, DH and Sommer, T.
Nature Cell Biology 4 (2): 134-139. 01 February 2002
Hip1 and Hippi participate in a novel cell death-signaling pathway.
Wanker, EE.
Developmental Cell 2 : 126-128. 01 February 2002
Selective norepinephrine reuptake inhibition as a human model of orthostatic intolerance.
Schroeder, C and Tank, J and Boschmann, M and Diedrich, A and Sharma, AM and Biaggioni, I and Luft, FC and Jordan, J.
Circulation 105 : 347-353. 22 January 2002
Neurohormonal activation and the chronic heart failure syndrome in adults with congenital heart disease.
Bolger, AP and Sharma, R and Li, W and Leenarts, M and Kalra, PR and Kemp, M and Coats, AJS and Anker, SD and Gatzoulis, MA.
Circulation 106 : 92-99. 01 January 2002
AMOP, a protein module aternativelly spliced in cancer cells.
Ciccarelli, FD and Doerks, T and Bork, P.
Trends in Biochemical Sciences 27 : 113-115. 01 January 2002
Alternative splicing and genome complexity.
Brett, D and Pospisil, H and Valcarel, J and Reich, J and Bork, P.
Nature Genetics 30 (1): 29-30. 01 January 2002
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.
Gerull, B and Gramlich, M and Atherton, J and McNabb, M and Trombitas, K and Sasse-Klaassen, S and Seidman, JG and Seidman, C and Granzier, H and Labeit, S and Frenneaux, M and Thierfelder, L.
Nature Genetics 30 : 201-204. 01 January 2002
CASH - a beta-helix domain widespread among carbohydrate-binding proteins.
Ciccarelli, FD and Copley, RR and Doerks, T and Russell, RB and Bork, P.
Trends in Biochemical Sciences 27 : 59-62. 01 January 2002
Cross-priming versus cross-tolerance: are two signals enough?
Blankenstein, T and Schueler, T.
Trends in Immunology 23 (4): 171-173. 01 January 2002
Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure - Results from 2 placebo-controlled studies.
Doehner, W and Schoene, N and Rauchhaus, M and Leyva-Leon, F and Pavitt, DV and Reaveley, DA and Schuler, G and Coats, AJS and Anker, SD and Hambrecht, R.
Circulation 105 (22): 2619-2624. 01 January 2002
The homeodomain factor Lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord.
Mueller, T and Brohmann, H and Pierani, A and Heppenstall, PA and Lewin, GR and Jessell, TM and Birchmeier, C.
Neuron 34 (4): 551-562. 01 January 2002
The low-density lipoprotein receptor gene family: a cellular Swiss army knife?
Nykjaer, A and Willnow, TE.
Trends in Cell Biology 12 (6): 273-280. 01 January 2002
Embryonic stem cells - The debate in Germany.
Reich, J.
Science 296 (5566): 265-265. 01 January 2002
Integration of genome data and protein structures: prediction of protein folds, protein interactions and 'molecular phenotypes' of single nucleotide polymorphisms (Reprinted from Current Opinion in Structural Biology, vol 11, pg 125-130, 2001).
Sunyaev, SR and Lathe, W and Bork, P.
Trends in Genetics Suppl. March : S19-S24. 01 January 2002
Genome organization: Teamed up for transcription.
von Mering, C and Bork, P.
Nature 417 (6891): 797-798. 01 January 2002
Association of genes to genetically inherited diseases using data mining.
Perez-Iratxeta, C and Bork, P and Andrade, MA.
Nature Genetics 31 : 316-319. 01 January 2002
BiP binding keeps ATF6 at bay.
Sommer, T and Jarosch, E.
Developmental Cell 3 : 1-2. 01 January 2002
Worldwide scientific publishing activity.
Perez-Iratxeta, C and Andrade, MA.
Science 297 : 519-519. 01 January 2002
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Oezcelik, C and Erdmann, B and Pilz, B and Wettschureck, N and Britsch, S and Huebner, N and Chien, KR and Birchmeier, C and Garratt, AN.
Proceedings of the National Academy of Sciences of the United States of America 99 : 8880-8885. 01 January 2002
Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huet anomaly).
Hoffmann, K and Dreger, CK and Olins, AL and Olins, DE and Shultz, LD and Lucke, B and Karl, H and Kaps, R and Mueller, D and Vaya, A and Aznar, J and Ware, RE and Cruz, NS and Lindner, TH and Herrmann, H and Reis, A and Sperling, K.
Nature Genetics 31 : 410-414. 01 January 2002
Catechol-O-methyltransferase and blood pressure in humans.
Jordan, J and Lipp, A and Tank, J and Schroeder, C and Stoffels, M and Franke, G and Diedrich, A and Arnold, G and Goldstein, DS and Sharma, AM and Luft, FC.
Circulation 106 : 460-465. 01 January 2002
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.
Schwarz-Romond, T and Asbrand, C and Bakkers, J and Kuhl, M and Schaeffer, HJ and Huelsken, J and Behrens, J and Hammerschmidt, M and Birchmeier, W.
Genes & Development 16 : 2073-2084. 01 January 2002
Phosphorylation by protein kinase CK2: A signaling switch for the caspase-inhibiting protein ARC.
Li, PF and Li, JC and Mueller, EC and Otto, A and Dietz, R and von Harsdorf, R.
Molecular Cell 10 : 247-258. 01 January 2002
Specific removal of beta1-adrenergic autoantibodies from patients with idiopathic dilated cardiomyopathy.
Wallukat, G and Mueller, J and Hetzer, R.
New England Journal of Medicine 347 : 1806. 01 January 2002
Paradoxical effect of sibutramine on autonomic cardiovascular regulation.
Birkenfeld, AL and Schroeder, C and Boschmann, M and Tank, J and Franke, G and Luft, FC and Biaggioni, I and Sharma, AM and Jordan, J.
Circulation 106 : 2459-2465. 01 January 2002
DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters.
Sporbert, A and Gahl, A and Ankerhold, R and Leonhardt, H and Cardoso, MC.
Molecular Cell 10 : 1355-1365. 01 January 2002
Human pituitary growth hormone and cancer risk.
Kalra, PR and Genth-Zotz, S and Coats, AJS and Anker, SD.
Lancet 360 : 1791-1792. 01 January 2002
A pH-sensitive histidine residue as control element for ligand release from HLA-DR molecules.
Roetzschke, O and Lau, JM and Hofstaetter, M and Falk, K and Strominger, JL.
Proceedings of the National Academy of Sciences of the United States of America 99 : 16946-16950. 01 January 2002
Studying gene function in eukaryotes by conditional gene inactivation.
Gossen, M and Bujard, H.
Annual Review of Genetics 36 : 153-173. 01 January 2002
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Generation of tumor-associated cytotoxic T lymphocytes requires interleukin 4 from CD8+ T cells.
Schueler, T and Kammertoens, T and Preiss, S and Debs, P and Noben-Trauth, N and Blankenstein, T.
Journal of Experimental Medicine 194 (12): 1767-1775. 17 December 2001
Tumor rejection by disturbing tumor stroma cell interactions.
Ibe, S and Qin, ZH and Schueler, T and Preiss, S and Blankenstein, T.
Journal of Experimental Medicine 194 (11): 1549-1559. 03 December 2001
Genomics boosts mouse molecular genetics.
Birchmeier, C and Treier, M.
Trends in Genetics 17 : 691-692. 01 December 2001
CNS synaptogenesis promoted by glia-derived cholesterol.
Mauch, DH and Naegler, K and Schumacher, S and Goeritz, C and Mueller, EC and Otto, A and Pfrieger, FW.
Science 294 (5545): 1354-1357. 09 November 2001
New aspects of Wnt signaling pathways in higher vertebrates.
Huelsken, J and Birchmeier, W.
Current Opinion in Genetics & Development 11 (5): 547-553. 01 October 2001
Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation.
Hammes, A and Guo, JK and Lutsch, G and Leheste, JR and Landrock, D and Ziegler, U and Gubler, MC and Schedl, A.
Cell 106 (3): 319-329. 10 August 2001
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
Grimm, J and Sachs, M and Britsch, S and Di Cesare, S and Schwarz-Romond, T and Birchmeier, W.
Journal of Cell Biology 154 (2): 345-354. 23 July 2001
Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation.
More, MI and Kirsch, FP and Rathjen, FG.
Journal of Cell Biology 154 (1): 187-196. 09 July 2001
BDNF but not NT-4 is required for normal flexion reflex plasticity and function.
Heppenstall, PA and Lewin, GR.
Proceedings of the National Academy of Sciences of the United States of America 98 : 8107-8112. 03 July 2001
Sox9 induces testis development in XX transgenic mice.
Vidal, VPI and Chaboissier, MC and de Rooij, DG and Schedl, A.
Nature Genetics 28 (3): 216-217. 01 July 2001
Inversions and the dynamics of eukaryotic gene order.
Huynen, MA and Snel, B and Bork, P.
Trends in Genetics 17 : 304-306. 01 June 2001
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
Huelsken, J and Vogel, R and Erdmann, B and Cotsarelis, G and Birchmeier, W.
Cell 105 (4): 533-545. 18 May 2001
Signal peptide cleavage of a type I membrane protein, HCMV US11, is dependent on its membrane anchor.
Rehm, A and Stern, P and Ploegh, HL and Tortorella, D.
EMBO Journal 20 : 1573-1582. 02 April 2001
A second locus for an axonal form of autosomal recessive Charcot-Marie-Tooth disease maps to chromosome 19q13.3.
Leal, A and Morera, B and del, Valle G and Heuss, D and Kayser, C and Berghoff, M and Villegas, R and Hernandez, E and Mendez, M and Hennies, HC and Neundoerfer, B and Barrantes, R and Reis, A and Rautenstrauss, B.
American Journal of Human Genetics 68 : 269-274. 01 January 2001
Integration of genome data and protein structures: prediction of protein folds, protein interactions and 'molecular phenotypes' of single nucleotide polymorphisms.
Sunyaev, SR and Lathe, W and Bork, P.
Current Opinion in Structural Biology 11 : 125-130. 01 January 2001
Activation of the Notch-regulated transcription factor CBF1/RBP-J kappa through the 13SE1A oncoprotein.
Ansieau, S and Strobl, LJ and Leutz, A.
Genes & Development 15 : 380-385. 01 January 2001
Enhanced ventilatory response to exercise in patients with chronic heart failure and preserved exercise tolerance - Marker of abnormal cardiorespiratory reflex control and predictor of poor prognosis.
Ponikowski, P and Francis, DP and Piepoli, MF and Davies, LC and Chua, TP and Davos, CH and Florea, V and Banasiak, W and Poole-Wilson, PA and Coats, AJS and Anker, SD.
Circulation 103 : 967-972. 01 January 2001
Chromatin remodeling in development and differentiation.
Mueller, C and Leutz, A.
Current Opinion in Genetics & Development 11 : 167-174. 01 January 2001
DDT - a novel domain in different transcription and chromosome remodeling factors.
Doerks, T and Copley, R and Bork, P.
Trends in Biochemical Sciences 26 : 145-146. 01 January 2001
Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia.
Nuernberg, P and Thiele, H and Chandler, D and Hoehne, W and Cunningham, ML and Ritter, H and Leschik, G and Uhlmann, K and Mischung, C and Harrop, K and Goldblatt, J and Borochowitz, ZU and Kotzot, D and Westermann, F and Mundlos, S and Braun, HS and Laing, N and Tinschert, S.
Nature Genetics 28 : 37-41. 01 January 2001
The transcription factor Sox10 is a key regulator of peripheral glial development.
Britsch, S and Goerich, DE and Riethmacher, D and Peirano, RI and Rossner, M and Nave, KA and Birchmeier, C and Wegner, M.
Genes & Development 15 (1): 66-78. 01 January 2001
LG/LNS domains: multiple functions - one business end?
Rudenko, G and Hohenester, E and Muller, YA.
Trends in Biochemical Sciences 26 : 363-368. 01 January 2001
Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p.
Walter, J and Urban, J and Volkwein, C and Sommer, T.
EMBO Journal 20 : 3124-3131. 01 January 2001
Identification, by homozygosity mapping, of a novel locus for autosomal recessive congenital ichthyosis on chromosome 17p, and evidence for further genetic heterogeneity.
Krebsova, A and Kuester, W and Lestringant, GG and Schulze, B and Hinz, B and Frossard, PM and Reis, A and Hennies, HC.
American Journal of Human Genetics 69 : 216-222. 01 January 2001
Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins.
Schwartz, T and Behlke, J and Lowenhaupt, K and Heineman, U and Rich, A.
Nature Structural Biology 8 : 761-765. 01 January 2001
Immunoglobulin superfamily receptors: cis-interactions, intracellular adapters and alternative splicing regulate adhesion.
Bruemmendorf, T and Lemmon, V.
Current Opinion in Cell Biology 13 : 611-618. 01 January 2001
XplorMed: a tool for exploring MEDLINE abstracts.
Perez-Iratxeta, C and Bork, P and Andrade, MA.
Trends in Biochemical Sciences 26 : 573-575. 01 January 2001
In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
Mehrhof, FB and Mueller, FU and Bergmann, MW and Li, PF and Wang, YB and Schmitz, W and Dietz, R and von Harsdorf, R.
Circulation 104 : 2088-2094. 01 January 2001
Adoptive tumor therapy with T lymphocytes enriched through an IFN-gamma capture assay.
Becker, C and Pohla, H and Frankenberger, B and Schueler, T and Assenmacher, M and Schendel, DJ and Blankenstein, T.
Nature Medicine 7 : 1159-1162. 01 January 2001
Cooperation between C/EBP alphaTBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation.
Pedersen, TA and Kowenz-Leutz, E and Leutz, A and Nerlov, C.
Genes & Development 15 : 3208-3216. 01 January 2001
Exciting you: signals from another kingdom.
Schipke, CG and Spier, AD.
Trends in Neurosciences 24 (12) : 692-692. 01 January 2001
The draft sequences. Filling in the gaps.
Bork, P and Copley, R.
Nature 409 : 818-820. 01 January 2001
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Plasma Cytokine Parameters and Mortality in Patients with Chronic Heart Failure.
Rauchhaus, M and Doehner, W and Francis, DP and Davos, C and Kemp, M and Liebenthal, C and Niebauer, J and Hooper, J and Volk, HD and Coats, AJS and Anker, SD.
Circulation 102 (25): 3060-3067. 19 December 2000
Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production.
Breitfeld, D and Ohl, L and Kremmer, E and Ellwart, J and Sallusto, F and Lipp, M and Foerster, R.
Journal of Experimental Medicine 192 (11): 1545-1551. 04 December 2000
Cell differentiation.
Rosenthal, N and Birchmeier, C.
Current Opinion in Cell Biology 12 : 717-718. 01 December 2000
Genes that control the development of migrating muscle precursor cells.
Birchmeier, C and Brohmann, H.
Current Opinion in Cell Biology 12 : 725-730. 01 December 2000
A major susceptibility locus for atopic dermatitis maps to chromosome 3q21.
Lee, YA and Wahn, U and Kehrt, R and Tarani, L and Businco, L and Gustafsson, D and Andersson, F and Oranje, AP and Wolkertstorfer, A and von Berg, A and Hoffmann, U and Kuester, W and Wienker, TF and Rueschendorf, F and Reis, A.
Nature Genetics 26 : 470-473. 01 December 2000
Severely impaired baroreflex-buffering in patients with monogenic hypertension and neurovascular contact.
Jordan, J and Toka, HR and Heusser, K and Toka, O and Shannon, JR and Tank, J and Diedrich, A and Stabroth, C and Stoffels, M and Naraghi, R and Oelkers, W and Schuster, H and Schobel, HP and Haller, H and Luft, FC.
Circulation 102 : 2611-2618. 21 November 2000
Structural genomics in Europe: slow start, strong finish?
Heinemann, U.
Nature Structural Biology 7 Suppl : 940-942. 01 November 2000
The mammalian sodium channel BNC1 is required for normal touch sensation.
Price, MP and Lewin, GR and McIlwrath, SL and Cheng, C and Xie, JH and Heppenstall, PA and Stucky, CL and Mannsfeldt, AG and Brennan, TJ and Drummond, HA and Qiao, J and Benson, CJ and Tarr, DE and Hrstka, RF and Yang, BL and Williamson, RA and Welsh, MJ.
Nature 407 (6807): 1007-1011. 26 October 2000
Severe mitral regurgitation after valve replacement as cause of pulmonary venous aneurysm.
Christow, SP and Dietz, R.
Circulation 102 (17): 2159-2160. 24 October 2000
Genomewide scan in German families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13.
Lee, YA and Rueschendorf, F and Windemuth, C and Schmitt-Egenolf, M and Stadelmann, A and Nuernberg, G and Staender, M and Wienker, TF and Reis, A and Traupe, H.
American Journal of Human Genetics 67 (4): 1020-1024. 01 October 2000
Cross-talk in kidney development.
Schedl, A and Hastie, ND.
Current Opinion in Genetics & Development 10 : 543-549. 01 October 2000
GRAM, a novel domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins.
Doerks, T and Strauss, M and Brendel, M and Bork, P.
Trends in Biochemical Sciences 25 : 483-485. 01 October 2000
Gene context conservation of a higher order than operons.
Lathe, WC and Snel, B and Bork, P.
Trends in Biochemical Sciences 25 : 474-479. 01 October 2000
Essential role of Gab1 for signaling by the c-Met receptor in vivo.
Sachs, M and Brohmann, H and Zechner, D and Mueller, T and Huelsken, J and Walther, I and Schaeper, U and Birchmeier, C and Birchmeier, W.
Journal of Cell Biology 150 (6): 1375-1384. 18 September 2000
The endotoxin-lipoprotein hypothesis.
Rauchhaus, M and Coats, AJS and Anker, SD.
Lancet 356 : 930-933. 09 September 2000
EST analysis online: WWW tools for detection of SNPs and alternative splice forms.
Brett, D and Lehmann, G and Hanke, J and Gross, S and Reich, J and Bork, P.
Trends in Genetics 16 : 416-418. 01 September 2000
SNP frequencies in human genes - an excess of rare alleles and differing modes of selection.
Sunyaev, SR and Lathe, WC and Ramensky, VE and Bork, P.
Trends in Genetics 16 : 335-337. 01 August 2000
Translational control of C/EBP alpha and C/EBP beta isoform expression.
Calkhoven, CF and Mueller, C and Leutz, A.
Genes & Development 14 : 1920-1932. 01 August 2000
A chemokine-driven positive feedback loop organizes lymphoid follicles.
Ansel, KM and Ngo, VN and Hyman, PL and Luther, SA and Foerster, R and Sedgwick, JD and Browning, JL and Lipp, M and Cyster, JG.
Nature 406 : 309-314. 20 July 2000
Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors.
Pesquero, JB and Araujo, RC and Heppenstall, PA and Stucky, CL and Silva, JA and Walther, T and Oliveira, SM and Pesquero, JL and Paiva, ACM and Calixto, JB and Lewin, GR and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 97 : 8140-8145. 05 July 2000
L27, a novel heterodimerization domain in receptor targeting proteins Lin-2 and Lin-7.
Doerks, T and Bork, P and Kamberov, E and Makarova, O and Muecke, S and Margolis, B.
Trends in Biochemical Sciences 25 : 317-318. 01 July 2000
Automated annotation of GPI anchor sites: case study C-elegans.
Eisenhaber, B and Bork, P and Yuan, YP and Loeffler, G and Eisenhaber, F.
Trends in Biochemical Sciences 25 : 340-341. 01 July 2000
A regulatory link between ER-associated protein degradation and the unfolded-protein response.
Friedlander, R and Jarosch, E and Urban, J and Volkwein, C and Sommer, T.
Nature Cell Biology 2 (7): 379-384. 01 July 2000
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
Schaeper, U and Gehring, NH and Fuchs, KP and Sachs, M and Kempkes, B and Birchmeier, W.
Journal of Cell Biology 149 (7): 1419-1432. 26 June 2000
More than 1,000 putative new human signalling proteins revealed by EST data mining.
Schultz, J and Doerks, T and Ponting, CP and Copley, RR and Bork, P.
Nature Genetics 25 : 201-204. 01 June 2000
Smooth-muscle contraction without smooth-muscle myosin.
Morano, I and Chai, GX and Baltas, LG and Lamounier-Zepter, V and Lutsch, G and Kott, M and Haase, H and Bader, M.
Nature Cell Biology 2 : 371-375. 01 June 2000
Sequences and topology. Genome and proteome informatics - Editorial overview.
Bork, P and Eisenberg, D.
Current Opinion in Structural Biology 10 : 341-342. 01 June 2000
Exploitation of gene context.
Huynen, MA and Snel, B and Lathe, W and Bork, P.
Current Opinion in Structural Biology 10 : 366-370. 01 June 2000
CD4+ T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFNgamma receptor expression by nonhematopoietic cells.
Qin, ZH and Blankenstein, T.
Immunity 12 : 677-686. 01 June 2000
AT1 receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor.
Dechend, R and Homuth, V and Wallukat, G and Kreuzer, J and Park, JK and Theuer, J and Juepner, A and Gulba, DC and Mackman, N and Haller, H and Luft, FC.
Circulation 101 : 2382-2387. 23 May 2000
Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1.
Janke, J and Schlueter, K and Jandrig, B and Theile, M and Koelble, K and Arnold, W and Grinstein, E and Schwartz, A and Estevez-Schwarz, L and Schlag, PM and Jockusch, BM and Scherneck, S.
Journal of Experimental Medicine 191 (10): 1675-1685. 15 May 2000
Towards a structural basis of human non-synonymous single nucleotide polymorphisms.
Sunyaev, SR and Ramensky, V and Bork, P.
Trends in Genetics 16 : 198-200. 01 May 2000
The value of magnetic resonance imaging of the left ventricular outflow tract in patients with hypertrophic obstructive cardiomyopathy after septal artery embolization.
Schulz-Menger, J and Strohm, O and Waigand, J and Uhlich, F and Dietz, R and Friedrich, MG.
Circulation 101 : 1764-1766. 18 April 2000
Dynamics of DNA replication factories in living cells.
Leonhardt, H and Rahn, HP and Weinzierl, P and Sporbert, A and Cremer, T and Zink, D and Cardoso, MC.
Journal of Cell Biology 149 (2): 271-279. 17 April 2000
A dual role of erbB2 in myelination and in expansion of the Schwann cell precursor pool.
Garratt, AN and Voiculescu, O and Topilko, P and Charnay, P and Birchmeier, C.
Journal of Cell Biology 148 (5): 1035-1046. 06 March 2000
A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks.
Schuster, S and Fell, DA and Dandekar, T.
Nature Biotechnology 18 (3): 326-332. 01 March 2000
Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.
Grishkovskaya, I and Avvakumov, GV and Sklenar, G and Dales, D and Hammond, GL and Muller, YA.
EMBO Journal 19 : 504-512. 15 February 2000
Requirement for beta-catenin in anterior-posterior axis formation in mice.
Huelsken, J and Vogel, R and Brinkmann, V and Erdmann, B and Birchmeier, C and Birchmeier, W.
Journal of Cell Biology 148 (3): 567-578. 07 February 2000
NF-kappaB and the innate immune response.
Hatada, EN and Krappmann, D and Scheidereit, C.
Current Opinion in Immunology 12 : 52-58. 01 February 2000
Immunohistochemical detection of lymph-node metastases.
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Lancet 355 : 144-145. 08 January 2000
Three-dimensional ultrasonography: new prospects for ultrasound imaging of bone.
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Lancet 355 : 116-117. 08 January 2000
A gene for an autosomal dominant scleroatrophic syndrome predisposing to skin cancer (Huriez Syndrome) maps to chromosome 4q23.
Lee, YA and Stevens, HP and Delaporte, E and Wahn, U and Reis, A.
American Journal of Human Genetics 66 : 326-330. 01 January 2000
A cholesterol-lowering gene maps to chromosome 13q.
Knoblauch, H and Mueller-Myhsok, B and Busjahn, A and Avi, LB and Baehring, S and Baron, H and Heath, SC and Uhlmann, R and Faulhaber, HD and Shpitzen, S and Aydin, A and Reshef, A and Rosenthal, M and Eliav, O and Muhl, A and Lowe, A and Schurr, D and Harats, D and Jeschke, E and Friedlander, Y and Schuster, H and Luft, FC and Leitersdorf, E.
American Journal of Human Genetics 66 : 157-166. 01 January 2000
NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue.
Pabst, O and Foerster, R and Lipp, M and Engel, H and Arnold, H-H.
EMBO Journal 19 : 2015-2023. 01 January 2000
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC.
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Nature Structural Biology 7 : 800-807. 01 January 2000
Genome evolution - gene fusion versus gene fission.
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Trends in Genetics 16 : 9-11. 01 January 2000
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Homozygosity mapping in families with Joubert syndrome identifies a locus on chromosome 9q34.3 and evidence for genetic heterogeneity.
Saar, K and Al-Gazali, L and Sztriha, L and Rueschendorf, F and Nur-E-Kamal, M and Reis, A and Bayoumi, R.
American Journal of Human Genetics 65 : 1666-1671. 01 December 1999
Two-dimensional IR correlation spectroscopy: Sequential events in the unfolding process of the lamda Cro-V55C repressor protein.
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Proceedings of the National Academy of Sciences of the United States of America 96 : 13153-13158. 09 November 1999
View from the east.
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Science 286 : 1087-1087. 05 November 1999
p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.
Li, PF and Dietz, R and von Harsdorf, R.
EMBO Journal 18 (21): 6027-6036. 01 November 1999
A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.
Kowenz-Leutz, E and Leutz, A.
Molecular Cell 4 : 735-743. 01 November 1999
DNA methyltransferase is actively retained in the cytoplasm during early development.
Cardoso, MC and Leonhardt, H.
Journal of Cell Biology 147 (1): 25-32. 04 October 1999
Dysferlin deletion in SJL mice (SJL-Dysf) defines a natural model for limb girdle muscular dystrophy 2B.
Bittner, RE and Anderson, LVB and Burkhardt, E and Bashir, R and Vafiadaki, E and Ivanova, S and Raffelsberger, T and Maerk, I and Hoeger, H and Jung, M and Karbasiyan, M and Storch, M and Lassmann, H and Moss, JA and Davison, K and Harrison, R and Bushby, KMD and Reis, A.
Nature Genetics 23 : 141-142. 01 October 1999
CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.
Foerster, R and Schubel, A and Breitfeld, D and Kremmer, E and Renner-Mueller, I and Wolf, E and Lipp, M.
Cell 99 (1): 23-33. 01 October 1999
Alternative splicing of human genes - more the rule than the exception?
Hanke, J and Brett, D and Zastrow, I and Aydin, A and Delbrueck, S and Lehmann, G and Luft, FC and Reich, J and Bork, P.
Trends in Genetics 15 : 389-390. 01 October 1999
Investigation of a family with autosomal dominant dilated cardiomyopathy defines a novel locus on chromosome 2q14-q22.
Jung, M and Poepping, I and Perrot, A and Ellmer, AE and Wienker, TF and Dietz, R and Reis, A and Osterziel, KJ.
American Journal of Human Genetics 65 : 1068-1077. 01 October 1999
Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development.
Woldeyesus, MT and Britsch, S and Riethmacher, D and Xu, L and Sonnenberg-Riethmacher, E and Abou-Rebyeh, F and Harvey, R and Caroni, P and Birchmeier, C.
Genes & Development 13 : 2538-2548. 01 October 1999
Coma in a park.
Pilz, B and Mesner, C and Baetgen, S and Luft, FC.
Lancet 354 : 1090. 25 September 1999
NF-kappaB p105 is a target of I kappaB kinases and controls signal induction of Bcl-3-p50 complexes.
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EMBO Journal 18 : 4766-4778. 01 September 1999
Pathological missense mutations of neural cell adhesion molecule L1 affect hemophilic and heterophilic binding activities.
De Angelis, E and MacFarlane, J and Du, JS and Yeo, G and Hicks, R and Rathjen, FG and Kenwrick, S and Bruemmendorf, T.
EMBO Journal 18 : 4744-4753. 01 September 1999
Diagnosis of hemochromatosis.
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Annals of Internal Medicine 131 : 311. 17 August 1999
Membrane microdomains and caveolae.
Kurzchalia, TV and Parton, RG.
Current Opinion in Cell Biology 11 : 424-431. 01 August 1999
Domains in plexins: links to integrins and transcription factors.
Bork, P and Doerks, T and Springer, TA and Snel, B.
Trends in Biochemical Sciences 24 : 261-263. 01 July 1999
Cytoskeletal dynamics in dendritic spines: direct modulation by glutamate receptors?
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Trends in Neurosciences 22 : 290-295. 01 July 1999
Separation of C/EBP alpha-mediated proliferation arrest and differentiation pathways.
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Proceedings of the National Academy of Sciences of the United States of America 96 : 7276-7281. 22 June 1999
A novel transactivation domain in parkin.
Morett, E and Bork, P.
Trends in Biochemical Sciences 24 : 229-231. 01 June 1999
Endotoxin and immune activation in chronic heart failure: a prospective cohort study.
Niebauer, J and Volk, HD and Kemp, M and Dominguez, M and Schumann, RR and Rauchhaus, M and Poole-Wilson, PA and Coats, AJS and Anker, SD.
Lancet 353 (9167): 1838-1842. 29 May 1999
Neurotractin, a novel neurite outgrowth-promoting Ig-like protein that interacts with CEPU-1 and LAMP.
Marg, A and Sirim, P and Spaltmann, F and Plagge, A and Kauselmann, G and Buck, F and Rathjen, FG and Bruemmendorf, T.
Journal of Cell Biology 145 (4): 865-876. 17 May 1999
YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis.
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Development 126 (9): 1845-1857. 01 May 1999
Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization.
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FASEB Journal 13 (8): 805-812. May 1999
The role of SF/HGF and c-Met in the development of skeletal muscle.
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Development 126 : 1621-1629. 01 April 1999
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor.
Wallukat, G and Homuth, V and Fischer, T and Lindschau, C and Horstkamp, B and Jupner, A and Baur, E and Nissen, E and Vetter, K and Neichel, D and Dudenhausen, JW and Haller, H and Luft, FC.
Journal of Clinical Investigation 103 (7): 945-952. April 1999
Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.
Schinke, M and Baltatu, O and Boehm, M and Peters, J and Rascher, W and Bricca, G and Lippoldt, A and Ganten, D and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 96 : 3975-3980. 30 March 1999
T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice.
Schueler, T and Qin, Z and Ibe, S and Noben-Trauth, N and Blankenstein, T.
Journal of Experimental Medicine 189 (5): 803-810. 01 March 1999
An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D-3.
Nykjaer, A and Dragun, D and Walther, D and Vorum, H and Jacobsen, C and Herz, J and Melsen, F and Christensen, EI and Willnow, TE.
Cell 96 (4): 507-515. 19 February 1999
Genetics and B-cell leukaemia.
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Lancet 353 : 3. 02 January 1999
Genome phylogeny based on gene content.
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Nature Genetics 21 : 108-110. 01 January 1999
Signaling from beta-adrenoceptor to L-type calcium channel: identification of a novel cardiac protein kinase A target possessing similarities to AHNAK.
Haase, H and Podzuweit, T and Lutsch, G and Hohaus, A and Kostka, S and Lindschau, C and Kott, M and Kraft, R and Morano, I.
FASEB Journal 13 : 2161-2172. 01 January 1999
Lateral gene transfer, genome surveys, and the phylogeny of prokaryotes.
Huynen, MA and Snel, B and Bork, P.
Science 286 : 1443a-1443. 01 January 1999
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Cutting edge of cardiomyopathy.
Poepping, I and Thalhammer, C and Pilz, B and Luft, FC.
Lancet 32 (9139): 1518-1518. 07 November 1998
Reconstitution of mammary gland development in vitro: Requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.
Niemann, C and Brinkmann, V and Spitzer, E and Hartmann, G and Sachs, M and Naundorf, H and Birchmeier, W.
Journal of Cell Biology 143 (2): 533-545. 19 October 1998
Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase.
Birchmeier, C and Gherardi, E.
Trends in Cell Biology 8 (10): 404-410. 01 October 1998
Signal transduction - Docking IkappaB kinases.
Scheidereit, C.
Nature 395 : 225-226. 17 September 1998
Conservation of gene order: a fingerprint of proteins that physically interact.
Dandekar, T and Snel, B and Huynen, M and Bork, P.
Trends in Biochemical Sciences 23 (9): 324-328. 01 September 1998
Dissection of complex molecular interactions of neurofascin with axonin-1, F11, and tenascin-R, which promote attachment and neurite formation of tectal cells.
Volkmer, H and Zacharias, U and Noerenberg, U and Rathjen, FG.
Journal of Cell Biology 142 : 1083-1093. 24 August 1998
Microdomains of GPI-anchored proteins in living cells revealed by crosslinking.
Friedrichson, T and Kurzchalia, TV.
Nature 394 (6695): 802-805. 20 August 1998
Insulin-like growth factor-I and risk of breast cancer.
Strohm, O and Osterziel, KJ and Dietz, R.
Lancet 352 (9126): 489-489. 08 August 1998
Families with autosomal dominant brachydactyly type E, short stature, and severe hypertension.
Toka, HR and Baehring, S and Chitayat, D and Melby, JC and Whitehead, R and Jeschke, E and Wienker, TF and Toka, O and Schuster, H and Luft, FC.
Annals of Internal Medicine 129 (3): 204-208. 01 August 1998
Interleukin 4 gene-defective mice reconstituted with wild-type bone marrow fail to produce normal immunoglobulin E levels.
Lange, C and Schueler, T and Blankenstein, T.
Journal of Experimental Medicine 187 (9): 1487-1493. 04 May 1998
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome.
Varon, R and Vissinga, C and Platzer, M and Cerosaletti, KM and Chrzanowska, KH and Saar, K and Beckmann, G and Seemanova, E and Cooper, PR and Nowak, NJ and Stumm, M and Weemaes, CMR and Gatti, RA and Wilson, RK and Digweed, M and Rosenthal, A and Sperling, K and Concannon, P and Reis, A.
Cell 93 (3): 467-476. 01 May 1998
Randomised, double-blind, placebo-controlled trial of human recombinant growth hormone in patients with chronic heart failure due to dilated cardiomyopathy.
Osterziel, KJ and Strohm, O and Schuler, J and Friedrich, M and Haenlein, D and Willenbrock, R and Anker, SD and Poole-Wilson, PA and Ranke, MB and Dietz, R.
Lancet 351 (9111): 1233-1237. 25 April 1998
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Behrens, J and Jerchow, BA and Wuertele, M and Grimm, J and Asbrand, C and Wirtz, R and Kuehl, M and Wedlich, D and Birchmeier, W.
Science 280 (5363): 596-599. 24 April 1998
Endothelial-cell permeability and protein kinase C in pre-eclampsia.
Haller, H and Hempel, A and Homuth, V and Mandelkow, A and Busjahn, A and Maasch, C and Drab, M and Lindschau, C and Juepner, A and Vetter, K and Dudenhausen, J and Luft, FC.
Lancet 351 (9107): 945-949. 28 March 1998
Wanted: subcellular localization of proteins based on sequence.
Eisenhaber, F and Bork, P.
Trends in Cell Biology 8 : 169-170. 01 January 1998
Predicting functions from protein sequences - where are the bottlenecks?
Bork, P and Koonin, EV.
Nature Genetics 18 : 313-318. 01 January 1998
The site-specific correction of genetic defects.
Strauss, M.
Nature Medicine 4 : 274-275. 01 January 1998
L-type calcium channel expression depends on the differentiated state of vascular smooth muscle cells.
Gollasch, M and Haase, H and Ried, C and Lindschau, C and Morano, I and Luft, FC and Haller, H.
FASEB Journal 12 : 593-601. 01 January 1998
B cells inhibit induction of T cell-dependent tumor immunity.
Qin, ZH and Richter, G and Schueler, T and Ibe, S and Cao, XT and Blankenstein, T.
Nature Medicine 4 : 627-630. 01 January 1998
Protein annotation: detective work for function prediction.
Doerks, T and Bairoch, A and Bork, P.
Trends in Genetics 14 : 248-250. 01 January 1998
Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation.
Engel, K and Kotlyarov, A and Gaestel, M.
EMBO Journal 17 : 3363-3371. 01 January 1998
The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system.
Britsch, S and Li, L and Kirchhoff, S and Theuring, F and Brinkmann, V and Birchmeier, C and Riethmacher, D.
Genes & Development 12 : 1825-1836. 01 January 1998
Reply: On slices, synaptosomes and dissociated neurones to study in vitro ageing physiology.
Verkhratsky, A and Toescu, EC.
Trends in Neurosciences 21 : 287-287. 01 January 1998
Calcium and neuronal ageing.
Verkhratsky, A and Toescu, EC.
Trends in Neurosciences 21 (1): 2-7. January 1998
Glial calcium: Homeostasis and signaling function.
Verkhratsky, A and Orkand, RK and Kettenmann, H.
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Role of Cue1p in ubiquitination and degradition at the ER surface.
Biederer, T and Volkwein, C and Sommer, T.
Science 278 (5344): 1806-1809. 05 December 1997
Severe neuropathies in mice with targeted mutations in the ErbB3 receptor.
Riethmacher, D and Sonnenberg-Riethmacher, E and Brinkmann, V and Yamaai, T and Lewin, GR and Birchmeier, C.
Nature 389 (6652): 725-730. 16 October 1997
The gene for autosomal dominant craniometaphyseal dysplasia maps to chromosome 5p and is distinct from the growth hormone receptor gene.
Nuernberg, P and Tinschert, S and Mrug, M and Hampe, J and Mueller, CR and Fuhrmann, E and Braun, HS and Reis, A.
American Journal of Human Genetics 61 (4): 918-923. October 1997
From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic acid and db-cAMP in vitro differentiation model.
Drab, M and Haller, H and Bychkov, R and Erdmann, B and Lindschau, C and Haase, H and Morano, I and Luft, FC and Wobus, AM.
FASEB Journal 11 (11): 905-915. September 1997
Localization of the gene causing keratolytic winter erythema to chromosome 8p22-p23, and evidence for a founder effect in south african afrikaans-speakers.
Starfield, M and Hennies, HC and Jung, M and Jenkins, T and Wienker, TF and Hull, P and Spurdle, A and Kuester, W and Ramsay, M and Reis, A.
American Journal of Human Genetics 61 (2): 370-378. August 1997
The gene for the ataxia telangiectasia variant, nijmegen breakage syndrome, maps to a 1 cm interval on chromosome 8q21.
Saar, K and Chrzanowska, KH and Stumm, M and Jung, M and Nuernberg, G and Wienker, TF and Seemanova, E and Wegner, RD and Reis, A and Sperling, K.
American Journal of Human Genetics 60 (3): 605-610. March 1997
Traumatic ventricular aneurysm.
Jordan, J and Dietz, R.
New England Journal of Medicine 336 (9): 625-625. 27 February 1997
Chicken acidic leucine-rich EGF-like domain containing brain protein (CALEB), a neural member of the EGF family of differentiation factors, is implicated in neurite formation.
Schumacher, S and Volkmer, H and Buck, F and Otto, A and Tarnok, A and Roth, S and Rathjen, FG.
Journal of Cell Biology 136 (4): 895-906. 24 February 1997
Cholesterol, hedgehog and embryogenesis.
Herz, J and Willnow, TE and Farese, RV.
Nature Genetics 15 (2): 123-124. February 1997
Mapping and use of a sequence that targets DNA ligase I to sites of DNA replication in vivo.
Cardoso, MC and Joseph, C and Rahn, HP and Reusch, R and Nadal-Ginard, B and Leonhardt, H.
Journal of Cell Biology 139 : 579-587. 01 January 1997
Alexander von Humboldt and the concept of animal electricity.
Kettenmann, H.
Trends in Neurosciences 20 : 239-242. 01 January 1997
Na+/Ca2+ exchanger modulates kainate- triggered Ca2+ signaling in Bergmann glial cells in situ.
Kirischuk, S and Kettenmann, H and Verkhratsky, A.
FASEB Journal 11 : 566-572. 01 January 1997
SPRY domains in ryanodine receptors (Ca2+ release channels).
Ponting, C and Schultz, J and Bork, P.
Trends in Biochemical Sciences 22 : 193-194. 01 January 1997
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
Bork, P and Hofmann, K and Bucher, P and Neuwald, A and Altschul, SF and Koonin, EV.
FASEB Journal 11 (1): 68-76. 01 January 1997
Secreted fringe like signaling molecules may be glycosyltransferases.
Yuan, YP and Schultz, J and Mlodzik, M and Bork, P.
Cell 88 : 9-11. 01 January 1997
Neurotrophins live or let die: Does p75NTR decide.
Carter, BD and Lewin, GR.
Neuron 18 : 187-190. 01 January 1997
Tumor necrosis factor-alpha and expression of the multidrug resistance-associated genes LRP and MRP.
Stein, U and Walther, W and Laurencot, CM and Scheffer, GL and Scheper, RJ and Shoemaker, RH.
Journal of the National Cancer Institute 89 : 807-813. 01 January 1997
Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death.
Sandig, V and Brand, K and Herwig, S and Lukas, J and Bartek, J and Strauss, M.
Nature Medicine 3 : 313-319. 01 January 1997
Deletion at 12p in a japanese child with brachydactyly overlaps the assigned locus of brachydactyly with hypertension in a turkish family.
Baehring, S and Nagai, T and Toka, HR and Nitz, I and Toka, O and Aydin, A and Muhl, A and Wienker, TF and Schuster, H and Luft, FC.
American Journal of Human Genetics 60 : 732-735. 01 January 1997
Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression.
Bargou, RC and Juerchott, K and Wagener, C and Bergmann, S and Metzner, S and Bommert, K and Mapara, MY and Winzer, KJ and Dietel, M and Doerken, B and Royer, HD.
Nature Medicine 3 : 447-450. 01 January 1997
Analysis of genetic linkage and somatic loss of heterozygosity in affected pairs of first-degree relatives.
Rohde, K and Teare, MD and Koref, MS.
American Journal of Human Genetics 61 : 418-422. 01 January 1997
Cytoplasmic signalling domains: the next generation.
Bork, P and Schultz, J and Ponting, CP.
Trends in Biochemical Sciences 22 : 296-298. 01 January 1997
The homeobox gene GBX2, a target of the myb oncogene, mediates autocrine growth and monocyte differentiation.
Kowenz-Leutz, E and Herr, P and Niss, K and Leutz, A.
Cell 91 : 185-195. 01 January 1997
A putative nucleic acid-binding domain in Werner's and Bloom's syndrome helicases.
Morozov, V and Mushegian, AR and Koonin, EV and Bork, P.
Trends in Biochemical Sciences 22 : 417-418. 01 January 1997
Endoplasmic reticulum degradation: reverse protein flow of no return.
Sommer, T and Wolf, DH.
FASEB Journal 11 : 1227-1233. 01 January 1997
Role of nonbilayer lipids in functions of cytochrome P450SCC (CYP11A1) studied in lipid vesicles.
Schwarz, D and Kisselev, P and Wessel, R and Pfeil, W.
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A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen.
Foerster, R and Mattis, A and Kremmer, E and Wolf, E and Brem, G and Lipp, M.
Cell 87 (6): 1037-1047. 13 December 1996
Different mechanisms control signal-induced degradation and basal turnover of the NF-kappab inhibitor ikappabalpha in vivo.
Krappmann, D and Wulczyn, FG and Scheidereit, C.
EMBO Journal 15 (23): 6716-6726. 02 December 1996
Intrastriatally injected c-fos antisense oligonucleotide interferes with striatonigral but not striatopallidal gamma-aminobutyric acid transmission in the conscious rat.
Sommer, W and Rimondini, R and O'Connor, W and Hansson, A and Ungerstedt, U and Fuxe, K.
Proceedings of the National Academy of Sciences of the United States of America 93 (24): 14134-14139. 26 November 1996
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Weidner, KM and Dicesare, S and Sachs, M and Brinkmann, V and Behrens, J and Birchmeier, W.
Nature 384 (6605): 173-176. 14 November 1996
Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites.
Volkmer, H and Leuschner, R and Zacharias, U and Rathjen, FG.
Journal of Cell Biology 135 (4): 1059-1069. November 1996
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
Ruiz, P and Brinkmann, V and Ledermann, B and Behrend, M and Grund, C and Thalhammer, C and Vogel, F and Birchmeier, C and Guenthert, U and Franke, WW and Birchmeier, W.
Journal of Cell Biology 135 (1): 215-225. October 1996
Functional interaction of beta-catenin with the transcription factor LEF-1.
Behrens, J and von Kries, JP and Kuehl, M and Bruhn, L and Wedlich, D and Grosschedl, R and Birchmeier, W.
Nature 382 (6592): 638-642. 15 August 1996
Calcium signalling in glial cells.
Verkhratsky, A and Kettenmann, H.
Trends in Neurosciences 19 (8): 346-352. 01 August 1996
BRCA1 protein products ... Functional motifs...
Koonin, EV and Altschul, SF and Bork, P.
Nature Genetics 13 (3): 266-268. 01 July 1996
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases.
Sachs, M and Weidner, KM and Brinkmann, V and Walther, I and Obermeier, A and Ullrich, A and Birchmeier, W.
Journal of Cell Biology 133 (5): 1095-1107. 03 June 1996
A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus.
Goerlich, D and Henklein, P and Laskey, RA and Hartmann, E.
EMBO Journal 15 (8): 1810-1817. 15 April 1996
Gestational diabetes.
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Lancet 347 (9003): 759-760. 16 March 1996
Blocking of transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in scid mice.
Bargou, RC and Wagener, C and Bommert, K and Arnold, W and Daniel, PT and Mapara, MY and Grinstein, E and Royer, HD and Doerken, B.
Journal of Experimental Medicine 183 (3): 1205-1213. 01 March 1996
The E2F transcription factor activates a replication-dependet human H2A gene in early S phase of the cell cycle.
Oswald, F and Dobner, T and Lipp, M.
Molecular and Cellular Biology 16 (5): 1889-1895. 01 January 1996
Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.
Biederer, T and Volkwein, C and Sommer, T.
EMBO Journal 15 : 2069-2076. 01 January 1996
A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S.cerevisiae.
Finke, K and Plath, K and Panzner, S and Prehn, S and Rapoport, TA and Hartmann, E and Sommer, T.
EMBO Journal 15 (7): 1482-1494. 01 January 1996
Sperm-egg binding protein or proto-oncogene?
Bork, P.
Science 271 (5254): 1431-1432. 01 January 1996
Ancient duplication of dna polymerase inferred from analysis of complete bacterial genomes.
Koonin, EV and Bork, P.
Trends in Biochemical Sciences 21 (4): 128-129. 01 January 1996
Are there similarities between the polarization of the c. elegans embryo and of an epithelial cell.
Kurzchalia, TV and Hartmann, E.
Trends in Cell Biology 6 (4): 131-132. 01 January 1996
Internal repeats in the BRCA2 protein sequence.
Bork, P and Blomberg, N and Nilges, M.
Nature Genetics 13 : 22-23. 01 January 1996
Severe autosomal dominant hypertension and brachydactyly in a unique turkish kindred maps to human chromosome 12.
Schuster, H and Wienker, TF and Baehring, S and Bilginturan, N and Toka, HR and Neitzel, H and Jeschke, E and Toka, O and Gilbert, D and Lowe, A and Ott, J and Haller, H and Luft, FC.
Nature Genetics 13 (1): 98-100. 01 January 1996
The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis.
Sonnenberg-Riethmacher, E and Walter, B and Riethmacher, D and Goedecke, S and Birchmeier, C.
Genes & Development 10 (10): 1184-1193. 01 January 1996
Reversal of multidrug resistance by transduction of cytokine genes into human colon carcinoma cells.
Stein, U and Walther, W and Shoemaker, RH.
Journal of the National Cancer Institute 88 : 1383-1392. 01 January 1996
Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease.
Rubattu, S and Volpe, M and Kreutz, R and Ganten, U and Ganten, D and Lindpaintner, K.
Nature Genetics 13 : 429-434. 01 January 1996
Beyond the neuronal circuitry.
Kettenmann, H.
Trends in Neurosciences 19 : 305-306. 01 January 1996
Pleckstrin's repeat performance: a novel domain in g protein signaling.
Ponting, CP and Bork, P.
Trends in Biochemical Sciences 21 : 245-246. 01 January 1996
Non-orthologous gene displacement.
Koonin, EV and Mushegian, AR and Bork, P.
Trends in Genetics 12 : 334-336. 01 January 1996
Go huntig in sequence databases but watch out for the traps.
Bork, P and Bairoch, A.
Trends in Genetics 12 : 425-427. 01 January 1996
Friedreich's atataxia protein: phylogenetic evidence for mitochondrial disfunction.
Gibson, T and Koonin, EV and Musco, G and Pastore, A and Bork, P.
Trends in Neurosciences 19 : 465-468. 01 January 1996
1995
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.
Brinkmann, V and Foroutan, H and Sachs, M and Weidner, KM and Birchmeier, W.
Journal of Cell Biology 131 (6 Pt. 1): 1573-1586. December 1995
Multiple essential functions of neuregulin in development.
Meyer, D and Birchmeier, C.
Nature 378 (6555): 386-390. 23 November 1995
Heat repeats in Huntington's disease protein.
Andrade, MA and Bork, P.
Nature Genetics 11 (2): 115-116. 01 October 1995
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.
Yang, Y and Spitzer, E and Meyer, D and Sachs, M and Niemann, C and Hartmann, G and Weidner, KM and Birchmeier, C and Birchmeier, W.
Journal of Cell Biology 131 (1): 215-226. October 1995
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud.
Bladt, F and Riethmacher, D and Isenmann, S and Aguzzi, A and Birchmeier, C.
Nature 376 (6543): 768-771. 31 August 1995
Characterization of functional domains of the tenascin-R (restrictin) polypeptide: cell attachment site, binding with F11 and enhancement of F11 mediated neurite outgrowth by tenascin-R.
Noerenberg, U and Hubert, M and Bruemmendorf, T and Tarnok, A and Rathjen, FG.
Journal of Cell Biology 130 (2): 473-484. July 1995
Posttranslational protein transport in yeast reconstituted with a purified complex of SEC proteins and KAR2P.
Panzner, S and Dreier, L and Hartmann, E and Kostka, S and Rapoport, TA.
Cell 81 (4): 561-570. 19 May 1995
Protein-rRNA binding features and their structural and functional implications in ribosomes as determined by cross- linking studies.
Urlaub, H and Kruft, V and Bischof, O and Mueller, EC and Wittmann-Liebold, B.
EMBO Journal 14 (18): 4578-4588. 01 January 1995
Guilt by insolubility - does a protein's detergent insolubility reflect a caveolar location?
Kurzchalia, TV and Hartmann, E and Dupree, P.
Trends in Cell Biology 5 : 187-189. 01 January 1995
Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmatic reticulum membrane.
Kutay, U and Ahnert-Hilger, G and Hartmann, E and Wiedenmann, B and Rapoport, TA.
EMBO Journal 14 : 217-223. 01 January 1995
Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library.
Lieber, A and Strauss, M.
Molecular and Cellular Biology 15 : 540-551. 01 January 1995
Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.
Weidner, KM and Sachs, M and Riethmacher, D and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 92 : 2597-2601. 01 January 1995
A phosphotyrosine interaction domain.
Bork, P and Margolis, B.
Cell 80 (5): 693-694. 01 January 1995
A ran-binding motif in nuclear pore proteins.
Hartmann, E and Goerlich, D.
Trends in Cell Biology 5 (5): 192-193. 01 January 1995
A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane.
Jungnickel, B and Rapoport, TA.
Cell 82 (2): 261-270. 01 January 1995
Circular permutations of protein sequence: not so rare?
Heinemann, U and Hahn, M.
Trends in Biochemical Sciences 20 (9): 349-350. 01 January 1995
NF-M (C/EBPbeta) induces eosinophilic differentiation and apoptosis in a hematopoietic progenitor cell line.
Mueller, C and Kowenz-Leutz, E and Grieser-Ade, S and Graf, T and Leutz, A.
EMBO Journal 14 (24): 6127-6135. 01 January 1995
Interleukin-2 as a neuroregulatory cytokine.
Hanisch, UK and Quirion, R.
Brain Research Brain Research Reviews 21 : 246-284. 01 January 1995
1994
Isolation of a protein that is essential for the first step of nuclear protein import.
Goerlich, D and Prehn, S and Laskey, RA and Hartmann, E.
Cell 79 (5): 767-778. 02 December 1994
The WW domain: a signalling site in dystrophin.
Bork, P and Sudol, M.
Trends in Biochemical Sciences 19 (12): 531-533. 01 December 1994
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
Huelsken, J and Birchmeier, W and Behrens, J.
Journal of Cell Biology 127 (6 Pt. 2): 2061-2069. December 1994
Novel mechanism of C/EBPbeta (NF-M) transcriptional control: activation through derepression.
Kowenz-Leutz, E and Twamley, G and Ansieau, S and Leutz, A.
Genes & Development 8 (22): 2781-2791. 15 November 1994
Members of the fatty acid binding protein family are differentiation factors for the mammary gland.
Yang, Y and Spitzer, E and Kenney, N and Zschiesche, W and Li, M and Kromminga, A and Mueller, T and Spener, F and Lezius, A and Veerkamp, JH and Smith, GH and Salomon, DS and Grosse, R.
Journal of Cell Biology 127 (4): 1097-1109. November 1994
Binding of ribosomes to the rough endoplasmic reticulum mediated by the sec61p-complex.
Kalies, KU and Goerlich, D and Rapoport, TA.
Journal of Cell Biology 126 (4): 925-934. August 1994
Crystal structure of CspA, the major cold shock protein of Escherichia coli.
Schindelin, H and Jiang, W and Inouye, M and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 91 (11): 5119-5123. 24 May 1994
Medical compared with surgical treatment for massive pulmonary embolism.
Gulba, D and Schmid, C and Borst, HG and Lichtlen, PR and Dietz, R and Luft, FC.
Lancet 343 (8897): 576-577. 05 March 1994
Role of adrenal renin in the regulation of adrenal steroidogenesis corticotropin.
Sander, M and Ganten, D and Mellon, SH.
Proceedings of the National Academy of Sciences of the United States of America 91 (1): 148-152. 04 January 1994
Stress- and mitogen-induced phosphorylation of the small heat shock protein Hsp25 by MAPKAP kinase 2 is not essential for chaperone properties and cellular thermoresistance.
Knauf, U and Jakob, U and Engel, K and Buchner, J and Gaestel, M.
EMBO Journal 13 : 54-60. 01 January 1994
Evolutionary conservation of components of the protein translocation complex.
Hartmann, E and Sommer, T and Prehn, S and Goerlich, D and Jentsch, S and Rapoport, TA.
Nature 367 : 654-657. 01 January 1994
Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane.
Mothes, W and Prehn, S and Rapoport, TA.
EMBO Journal 13 : 3973-3982. 01 January 1994
Native-like in vivo folding of a circularly permuted jellyroll protein shown by crystal structure analysis.
Hahn, M and Piotukh, K and Borriss, R and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 91 : 10417-10421. 01 January 1994
Transgenic rats: new experimental models for the study of candidate genes in hypertension research.
Paul, M and Wagner, J and Hoffmann, S and Urata, H and Ganten, D.
Annual Review of Physiology 56 : 811-829. 1994
1993
Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane.
Goerlich, D and Rapoport, TA.
Cell 75 (4): 615-630. 19 November 1993
Expression of tumor necrosis factor by different tumor cell lines results either in tumor suppression or augmented metastasis.
Qin, Z and Krueger-Krasagakes, S and Kunzendorf, U and Hock, H and Diamantstein, T and Blankenstein, T.
Journal of Experimental Medicine 178 (1): 355-360. 01 July 1993
Characterization of a novel Hodgkin cell-line, HD-MyZ, HD-Myr, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.
Bargou, RC and Mapara, MY and Zugck, C and Daniel, PT and Pawlita, M and Doehner, H and Doerken, B.
Journal of Experimental Medicine 177 (5): 1257-1268. 01 May 1993
An adhesive domain detected in functionally diverse receptors.
Beckmann, G and Bork, P.
Trends in Biochemical Sciences 18 : 40-41. 01 January 1993
Isoenzyme BB of glycogen phosphorylase b myocardial infarction.
Rabitzsch, G and Mair, J and Lechleitner, P and Noll, F and Hofmann, U and Krause, E-G and Dienstl, F and Puschendorf, B.
Lancet 341 : 1032-1033. 01 January 1993
1992
Transport of proteins across the endoplasmic reticulum membrane.
Rapoport, TA.
Science 258 (5084): 931-936. 06 November 1992
A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation.
Goerlich, D and Prehn, S and Hartmann, E and Kalies, KU and Rapoport, TA.
Cell 71 (3): 489-503. 30 October 1992
Yeast Sec-proteins interact with polypeptides traversing the endoplasmic reticulum membrane.
Muesch, A and Wiedmann, M and Rapoport, TA.
Cell 69 : 343-352. 01 January 1992
A protein of the endoplasmic reticulum involved early in polypeptide translocation.
Goerlich, D and Hartmann, E and Prehn, S and Rapoport, TA.
Nature 357 : 47-52. 01 January 1992
Signal sequence identified.
Hartmann, E and Rapoport, TA and Prehn, S.
Nature 358 : 198. 01 January 1992
Proposed acquisition of an animal protein domain by bacteria.
Bork, P and Doolittle, RF.
Proceedings of the National Academy of Sciences of the United States of America 89 : 8990-8994. 01 January 1992
This list was generated on Wed May 16 01:28:11 2012 CEST.
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