Article
Socio-affective communication in Tph2-deficient rat pups: communal nesting aggravates growth retardation despite ameliorating maternal affiliation deficits.
Wang, T., Homberg, J.R., Boreggio, L., Samina, M.C.F., Castro, R.C.R., Kolk, S.M., Alenina, N., Bader, M., Dai, J. and Wöhr, M.
Molecular Autism 15
(1): 50.
29 November 2024
Transgenic rat with ubiquitous expression of angiotensin-(1-7)-producing fusion protein: a new tool to study the role of protective arm of the renin-angiotensin system in the pathophysiology of cardio-renal diseases.
Červenka, L., Husková, Z., Kikerlová, S., Gawrys, O., Vacková, Š., Škaroupková, P., Sadowski, J., Miklovič, M., Molnár, M., Táborský, M., Melenovský, V. and Bader, M.
Hypertension Research
13 November 2024
(In Press)
Normal male fertility in a mouse model of KPNA2 deficiency.
Rother, F., Abu Hweidi, D., Hartmann, E. and Bader, M.
PLoS ONE 19
(10): e0304189.
18 October 2024
Serotonin drives aggression and social behaviours of laboratory mice in a semi-natural environment.
Rivalan, M., Alonso, L., Mosienko, V., Bey, P., Hyde, A., Bader, M., Winter, Y. and Alenina, N.
Frontiers in Behavioral Neuroscience 18
18 September 2024
ACE2 knockout mice are resistant to high-fat diet-induced obesity in an age-dependent manner.
Nunes-Souza, V., Alenina, N., Qadri, F., Mosienko, V., Santos, R.A.S., Bader, M. and Rabelo, L.A.
International Journal of Molecular Sciences 25
(17): 9515.
1 September 2024
Angiotensin-(1-12): does it exist? A critical evaluation in humans, rats, and mice.
Rodrigues, A.F., Domenig, O., Poglitsch, M., Bader, M. and Danser, A.H.J.
Hypertension 81
(8): 1776-1784.
August 2024
Novel tryptophan hydroxylase inhibitor TPT-001 reverses PAH, vascular remodeling, and proliferative-proinflammatory gene expression.
Legchenko, E., Chouvarine, P., Qadri, F., Specker, E., Nazaré, M., Wesolowski, R., Matthes, S., Bader, M. and Hansmann, G.
JACC: Basic to Translational Science 9
(7): 890-902.
July 2024
Functional autoantibodies against G protein-coupled receptors in hepatic and pulmonary hypertensions in human schistosomiasis.
Botoni, F.A., Lambertucci, J.R., Santos, R.A.S., Müller, J., Talvani, A. and Wallukat, G.
Frontiers in Immunology 15
: 1404384.
17 June 2024
Role of kinin receptors in skin pigmentation.
Ferreira, J.C.P., Soley, B.S., Pawloski, P.L., Moreira, C.G., Pesquero, J.B., Bader, M., Calixto, J.B., Cabrini, D.A. and Otuki, M.F.
European Journal of Pharmacology 973
: 176537.
15 June 2024
TPT-004, a next-generation inhibitor of tryptophan hydroxylase, ameliorates pulmonary arterial hypertension in rats.
Wesolowski, R., Pleimes, D., Specker, E. and Bader, M.
Journal of the American Heart Association 13
(10): e034240.
21 May 2024
Poor decision making and sociability impairment following central serotonin reduction in inducible TPH2-knockdown rats.
Alonso, L., Peeva, P., Fernández-del Valle Alquicira, T., Erdelyi, N., Gil Nolskog, Á., Bader, M., Winter, Y., Alenina, N. and Rivalan, M.
International Journal of Molecular Sciences 25
(9): 5003.
May 2024
Karyopherin α2 is a maternal effect gene required for early embryonic development and female fertility in mice.
Rother, F., Depping, R., Popova, E., Huegel, S., Heiler, A., Hartmann, E. and Bader, M.
FASEB Journal 38
(8): e23623.
30 April 2024
Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors.
Amado Costa, L., Oliveira Amaral, L.B., Mourão, F.A.G., Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Hormones and Behavior 163
: 105551.
27 April 2024
Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N., Bader, M., Willnow, T.E., Wiedenmann, B. and Sigal, M.
Frontiers in Endocrinology 15
: 1331231.
17 April 2024
Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Yalcin, F., Haneke, H., Efe, I.E., Kuhrt, L.D., Motta, E., Nickl, B., Flüh, C., Synowitz, M., Dzaye, O., Bader, M. and Kettenmann, H.
Acta Neuropathologica Communications 12
(1): 50.
2 April 2024
Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome.
Chan, J.C., Alenina, N., Cunningham, A.M., Ramakrishnan, A., Shen, Li, Bader, M. and Maze, I.
Journal of Molecular Biology 436
(7): 168454.
1 April 2024
Effects of bradykinin B2 receptor ablation from tyrosine hydroxylase cells on behavioral and motor aspects in male and female mice.
Franco, T.M., Tavares, M.R., Novaes, L.S., Munhoz, C.D., Peixoto-Santos, J.E., Araujo, R.C., Donato, J., Bader, M. and Wasinski, F.
International Journal of Molecular Sciences 25
(3): 1490.
25 January 2024
Kinin B1 receptor modulates glucose homeostasis and physical exercise capacity by altering adrenal catecholamine synthesis and secretion.
Gregnani, M.F., Budu, A., Batista, R.O., Ornellas, F.H., Estrela, G.R., Arruda, A.C., Freitas-Lima, L.C., Kremer, J.L., Favaroni Mendes, L.A., Casarini, D.E., Lotfi, C.F.P., Oyama, L.M., Bader, M. and Araujo, R.C.
Molecular and Cellular Endocrinology 579
: 112085.
1 January 2024
GPER activation attenuates cardiac dysfunction by upregulating the SIRT1/3-AMPK-UCP2 pathway in postmenopausal diabetic rats.
Azizian, H., Farhadi, Z., Bader, M., Ghalenoei, J.A., Ghafari, M.A. and Mahmoodzadeh, S.
PLoS ONE 18
(12): e0293630.
22 December 2023
Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain.
Alves-Silva, T., Húngaro, T.G.R., Freitas-Lima, L.C., de Melo Arthur, G., Arruda, A.C., Santos, R.B., Oyama, L.M., Mori, M.A.S., Bader, M. and Araujo, R.C.
iScience 26
(12): 108409.
15 December 2023
Ethanol deprivation and central 5-HT deficiency differentially affect the mRNA editing of the 5-HT(2C) receptor in the mouse brain.
Zaniewska, M., Alenina, N., Fröhler, S., Chen, W. and Bader, M.
Pharmacological Reports 75
(6): 1502-1521.
December 2023
The effect of brain serotonin deficit (TPH2-KO) on the expression and activity of liver cytochrome P450 enzymes in aging male Dark Agouti rats.
Haduch, A., Bromek, E., Kuban, W., Basińska-Ziobroń, A., Danek, P.J., Alenina, N., Bader, M. and Daniel, W.A.
Pharmacological Reports 75
(6): 1522-1532.
December 2023
Structure-based design of xanthine-imidazopyridines and -imidazothiazoles as highly potent and in vivo efficacious tryptophan hydroxylase inhibitors.
Specker, E., Wesolowski, R., Schütz, A., Matthes, S., Mallow, K., Wasinska-Kalwa, M., Winkler, L., Oder, A., Alenina, N., Pleimes, D., von Kries, J.P., Heinemann, U., Bader, M. and Nazaré, M.
Journal of Medicinal Chemistry 66
(21): 14866-14896.
9 November 2023
Functional assay for assessment of agonistic or antagonistic activity of angiotensin AT(2) receptor ligands reveals that EMA401 and PD123319 have agonistic properties.
Peluso, A.A., Souza Silva, I.M., Villela, D.C., Hansen, P.B.L., Hallberg, A., Bader, M., Santos, R., Sumners, C. and Muscha Steckelings, U.
Biochemical Pharmacology 216
: 115793.
October 2023
G-protein-coupled receptor MAS DeLETION produces a preeclampsia-like phenotype in FVB/N mice.
Vieira Pimentel, R.L., Braga, J.F., Velloso, E.P.P., Lautner, R.Q., Oliveira, M.L., Todiras, M., Alenina, N., Bader, M., de Sousa, F.G., Beier, S.L. and Souza Dos Santos, R.A.
Clinical Science 137
(16): 1249-1263.
August 2023
Kinin receptors regulate skeletal muscle regeneration: differential effects for B1 and B2 receptors.
Martins, L., Amorim, W.W., Gregnani, M.F., de Carvalho Araújo, R., Qadri, F., Bader, M. and Pesquero, J.B.
Inflammation Research 72
(8): 1583-1601.
August 2023
Transgenic angiotensin-converting enzyme 2 overexpression in the rat vasculature protects kidneys from ageing-induced injury.
Sanad, A.M., Qadri, F., Popova, E., Rodrigues, A.F., Heinbokel, T., Quach, S., Schulz, A., Bachmann, S., Kreutz, R., Alenina, N. and Bader, M.
Kidney International 104
(2): 293-304.
August 2023
Angiotensin deficient FVB/N mice are normotensive.
Rodrigues, A.F., Todiras, M., Qadri, F., Alenina, N. and Bader, M.
British Journal of Pharmacology 180
(14): 1843-1861.
July 2023
Angiotensin-(1-7) mediated calcium signalling by MAS.
Sureshkumar, P., Souza dos Santos, R.A., Alenina, N., Mergler, S. and Bader, M.
Peptides 165
: 171010.
July 2023
Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G., Bartolomaeus, H., Rauch, A., Chen, C.Y., N'Diaye, G., Löber, U., Bartolomaeus, T.U.P., Fritsche-Guenther, R., Rodrigues, A.F., Yarritu, A., Zhong, C., Fei, L., Tsvetkov, D., Todiras, M., Park, J.K., Markó, L., Maifeld, A., Patzak, A., Bader, M., Kempa, S., Kirwan, J.A., Forslund, S.K., Müller, D.N. and Wilck, N.
Cardiovascular Research 119
(6): 1441-1452.
May 2023
Brown adipose tissue transcriptome unveils an important role of the Beta-alanine/alamandine receptor, MrgD, in metabolism.
Cerri, G.C., Santos, S.H.S., Bader, M. and Dos Santos, R.A.S.
Journal of nutritional biochemistry 114
: 109268.
April 2023
Studies in zebrafish and rat models support dual blockade of EP2 and EP4 (prostaglandin E(2) receptors type 2 and 4) for renoprotection in glomerular hyperfiltration and albuminuria.
Kourpa, A., Schulz, A., Mangelsen, E., Kaiser-Graf, D., Koppers, N., Stoll, M., Rothe, M., Bader, M., Purfürst, B., Kunz, S., Gladytz, T., Niendorf, T., Bachmann, S., Mutig, K., Bolbrinker, J., Panakova, D. and Kreutz, R.
Hypertension 80
(4): 771-782.
April 2023
Tryptophan hydroxylase-2-mediated serotonin biosynthesis suppresses cell reprogramming into pluripotent state.
Sinenko, S.A., Kuzmin, A.A., Skvortsova, E.V., Ponomartsev, S.V., Efimova, E.V., Bader, M., Alenina, N. and Tomilin, A.N.
International Journal of Molecular Sciences 24
(5): 4862.
2 March 2023
Constitutive depletion of brain serotonin differentially affects rats’ social and cognitive abilities.
Alonso, L., Peeva, P., Stasko, S., Bader, M., Alenina, N., Winter, Y. and Rivalan, M.
iScience 26
(2): 105998.
17 February 2023
Angiotensin receptor-neprilysin inhibitor improves coronary collateral perfusion.
Li, K., Kratzmann, V., Dai, M., Gatzke, N., Rocic, P., Bramlage, P., Grisk, O., Lubomirov, L.T., Hoffmeister, M., Lauxmann, M.A., Ritter, O., Buschmann, E., Bader, M., Persson, A.B., Buschmann, I. and Hillmeister, P.
Frontiers in Cardiovascular Medicine 9
: 981333.
3 February 2023
B2 cells contribute to hypertension and natural killer cell activation possibly via AT1-AA in response to placental ischemia.
Herrock, O.T., Deer, E., Amaral, L.M., Campbell, N., Lemon, J., Ingram, N., Cornelius, D.C., Turner, T., Fitzgerald, S., Ibrahim, T., Dechend, R., Wallukat, G. and LaMarca, B.
American Journal of Physiology Renal Physiology 324
(2): F179-F192.
February 2023
Circulating angiotensin II type I receptor – autoantibodies in diabetic pregnancies.
Linge, L.L., Sugulle, M., Wallukat, G., Dechend, R. and Staff, A.C.
Journal of Reproductive Immunology 155
: 103777.
February 2023
Impact of genetic deletion of MrgD or Mas receptors in depressive-like behaviour in mice.
Becari, L., Fonseca, M.L.A., Gonçalves, S.C.A, Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Acta Neuropsychiatrica 35
(1): 27-34.
February 2023
Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice.
Jansch, M., Lubomirov, L.T., Trum, M., Williams, T., Schmitt, J., Schuh, K., Qadri, F., Maier, L.S., Bader, M. and Ritter, O.
FEBS Open Bio 13
(1): 118-132.
January 2023
Transgenic rat with overproduction of ubiquitous angiotensin-(1-7) presents neuroprotection in a model of ischemia and reperfusion.
Kangussu, L.M., Almeida-Santos, A.F., Fernandes, L.F., Alenina, N., Bader, M., Santos, R.A.S., Massensini, A.R. and Campagnole-Santos, M.J.
Brain Research Bulletin 192
: 184-191.
January 2023
In vitro galactose impairs energy metabolism in the brain of young rats: protective role of antioxidants.
Delwing-de Lima, D., Sasso, S., Delwing-Dal Magro, D., Pereira, N.R., Rodrigues, A.F., Schmitz, F., Manoel Pereira, E., Schramm do Nascimento, M.A. and Wyse, A.T.S.
Nucleosides Nucleotides & Nucleic Acids 42
(12): 967-985.
2023
Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M., Mücke, M.B., Pallien, T., Markó, L., Sholokh, A., Schächterle, C., Aydin, A., Kidd, A., Walter, S., Esmati, Y., McMurray, B.J., Lato, D.F., Sunaga-Franze, D.Y., Dierks, P.H., Flores, B.I.M., Walker-Gray, R., Gong, M., Merticariu, C., Zühlke, K., Russwurm, M., Liu, T., Batolomaeus, T.U.P., Pautz, S., Schelenz, S., Taube, M., Napieczynska, H., Heuser, A., Eichhorst, J., Lehmann, M., Miller, D.C., Diecke, S., Qadri, F., Popova, E., Langanki, R., Movsesian, M.A., Herberg, F.W., Forslund, S.K., Müller, D.N., Borodina, T., Maass, P.G., Bähring, S., Hübner, N., Bader, M. and Klussmann, E.
Circulation 146
(23): 1758-1778.
6 December 2022
Angiotensin 1-7 increases fiber cross sectional area and force in juvenile mouse skeletal muscle.
Albadrani, H., Ammar, T., Rajgara, R., Bader, M., Wiper-Bergeron, N. and Renaud, J.M.
American Journal of Physiology Cell Physiology 323
(6): C1681-C1696.
December 2022
Kinin B1 receptor modulates mitochondrial activity responsivity in fasting and voluntary exercise.
Arruda, A.C., Budu, A., de Menezes, T.N., Bader, M., Araujo, R.C. and Freitas-Lima, L.C.
Life Sciences 309
: 121034.
15 November 2022
Quantitative phosphoproteomics of the angiotensin AT(2)-receptor signaling network identifies HDAC1 (Histone-Deacetylase-1) and p53 as mediators of antiproliferation and apoptosis.
Peluso, A.A.B., Kempf, S.J., Verano-Braga, T., Rodrigues-Ribeiro, L., Johansen, L.E., Hansen, M.R., Kitlen, G., Haugaard, A.H., Sumners, C., Ditzel, H.J., Santos, R.A., Bader, M., Larsen, M.R. and Steckelings, U.M.
Hypertension 79
(11): 2530-2541.
November 2022
Functional antibodies against G-protein coupled receptors in Beagle dogs infected with two different strains of Trypanosoma cruzi.
Wallukat, G., Botoni, F.A., Rocha, M.O.C., Louise, V., Müller, J. and Talvani, A.
Frontiers in Immunology 13
: 926682.
25 October 2022
Role of Gpnmb in atherosclerosis of female mice.
Nickl, B., Qadri, F. and Bader, M.
Biochemical and Biophysical Research Communications 621
: 20-24.
17 September 2022
In vivo skin regeneration and wound healing using cell micro-transplantation.
Nanić, L., Cedilak, A., Vidaček, N.Š., Gruber, F., Huzak, M., Bader, M. and Rubelj, I.
Pharmaceutics 14
(9): 1955.
15 September 2022
Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
Specker, E., Matthes, S., Wesolowski, R., Schütz, A., Grohmann, M., Alenina, N., Pleimes, D., Mallow, K., Neuenschwander, M., Gogolin, A., Weise, M., Pfeifer, J., Ziebart, N., Heinemann, U., von Kries, J.P., Nazaré, M. and Bader, M.
Journal of Medicinal Chemistry 65
(16): 11126-11149.
25 August 2022
Hemodynamic stress-induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein.
Mohamed, B.A., Elkenani, M., Mobarak, S., Marques Rodrigues, D., Annamalai, K., Schnelle, M., Bader, M., Hasenfuss, G. and Toischer, K.
Journal of Cellular and Molecular Medicine 26
(16): 4440-4452.
August 2022
Role of endothelial kinin B(1) receptor on the membrane potential of transgenic rat aorta.
Batista, C., Sales, V.M., Merino, V.F., Bader, M., Feres, T. and Pesquero, J.B.
Physiological Research 71
(4): 477-487.
August 2022
Serotonin limits generation of chromaffin cells during adrenal organ development.
Kameneva, P., Melnikova, V.I., Kastriti, M.E., Kurtova, A., Kryukov, E., Murtazina, A., Faure, L., Poverennaya, I., Artemov, A.V., Kalinina, T.S., Kudryashov, N.V., Bader, M., Skoda, J., Chlapek, P., Curylova, L., Sourada, L., Neradil, J., Tesarova, M., Pasqualetti, M., Gaspar, P., Yakushov, V.D., Sheftel, B.I., Zikmund, T., Kaiser, J., Fried, K., Alenina, N., Voronezhskaya, E.E. and Adameyko, I.
Nature Communications 13
(1): 2901.
25 May 2022
Peripheral serotonin deficiency affects anxiety-like behavior and the molecular response to an acute challenge in rats.
Sbrini, G., Hanswijk, S.I., Brivio, P., Middelman, A., Bader, M., Fumagalli, F., Alenina, N., Homberg, J.R. and Calabrese, F.
International Journal of Molecular Sciences 23
(9): 4941.
29 April 2022
Tph2 gene expression defines ethanol drinking behavior in mice.
Zaniewska, M., Mosienko, V., Bader, M. and Alenina, N.
Cells 11
(5): 874.
3 March 2022
Placental CD4(+) T cells from preeclamptic patients cause autoantibodies to the angiotensin II type I receptor and hypertension in a pregnant rat model of preeclampsia.
Reeve, K.E., Deer, E., Amaral, L.M., Cornelius, D.C., Herrock, O., Harmon, A.C., Campbell, N., Fitzgerald, S., Ibrahim, T., Wallukat, G., Dechend, R. and LaMarca, B.
Exploration of Medicine 3
: 99-111.
25 February 2022
Targeting angiotensin type 2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice.
Mohammed, M., Johnson, D.N., Wang, L.A., Harden, S.W., Sheng, W., Spector, E.A., Elsaafien, K., Bader, M., Steckelings, U.M., Scott, K.A., Frazier, C.J., Sumners, C., Krause, E.G. and de Kloet, A.D.
Cardiovascular Research 118
(3): 883-896.
21 February 2022
Myogenic vasoconstriction requires canonical G(q/11) signaling of the angiotensin II type 1 receptor.
Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y.M., Schleifenbaum, J., Bader, M., Welsh, D.G., Huang, Y. and Gollasch, M.
Journal of the American Heart Association 11
(4): e022070.
15 February 2022
Carbon-mixed dental cement for fixing fiber optic ferrules prevents visually triggered locomotive enhancement in mice upon optogenetic stimulation.
Araragi, N., Alenina, N. and Bader, M.
Heliyon 8
(1): e08692.
January 2022
Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension.
Grabowski, K., Herlan, L., Witten, A., Qadri, F., Eisenreich, A., Lindner, D., Schädlich, M., Schulz, A., Subrova, J., Mhatre, K.N., Primessnig, U., Plehm, R., van Linthout, S., Escher, F., Bader, M., Stoll, M., Westermann, D., Heinzel, F.R. and Kreutz, R.
Hypertension Research 45
: 292-307.
January 2022
Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats.
Haduch, A., Danek, P.J., Kuban, W., Pukło, R., Alenina, N., Gołębiowska, J., Popik, P., Bader, M. and Daniel, W.A.
Neurochemistry International 152
: 105223.
January 2022
(Pro)renin receptor inhibition reduces plasma cholesterol and triglycerides but does not attenuate atherosclerosis in atherosclerotic mice.
Ye, D., Yang, X., Ren, L., Lu, H.S., Sun, Y., Lin, H., Tan, L., Wang, N., Nguyen, G., Bader, M., Mullick, A.E., Danser, A.H.J., Daugherty, A., Jiang, Y., Sun, Y., Li, F. and Lu, X.
Frontiers in Cardiovascular Medicine 8
: 725203.
24 December 2021
Angiotensin 1-7 prevents the excessive force loss resulting from 14- and 28-day denervation in mouse EDL and soleus muscle.
Albadrani, H., Ammar, T., Bader, M. and Renaud, J.M.
Journal of General Physiology 153
(12): e201912556.
6 December 2021
Diabetic pregnancy as a novel risk factor for cardiac dysfunction in the offspring-the heart as a target for fetal programming in rats.
Schütte, T., Kedziora, S.M., Haase, N., Herse, F., Alenina, N., Müller, D.N., Bader, M., Schupp, M., Dechend, R., Golic, M. and Kräker, K.
Diabetologia 64
(12): 2829-2842.
December 2021
Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M., Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M., Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A., Scheidereit, C., Butter, C., Felix, S.B., Otto, O., Luft, F.C., Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12
(6): 1653-1668.
December 2021
The receptor AT1 appears to be important for the maintenance of bone mass and AT2 receptor function in periodontal bone loss appears to be regulated by AT1 receptor.
Lima, M.L.S., Martins, A.A., Medeiros, C.A.C.X., Guerra, G.C.B., Santos, R., Bader, M., Pirih, F.Q., Araújo Júnior, R.F., Brito, G.A.C., Leitão, R.F.C., Silva, R.A., Barbosa, S.J.A., Melo, R.C.O. and Araújo, A.A.
International Journal of Molecular Sciences 22
(23): 12849.
27 November 2021
Enduring effects of conditional brain serotonin knockdown, followed by recovery, on adult rat neurogenesis and behavior.
Sidorova, M., Kronenberg, G., Matthes, S., Petermann, M., Hellweg, R., Tuchina, O., Bader, M., Alenina, N. and Klempin, F.
Cells 10
(11): 3240.
19 November 2021
In vivo renin activity imaging in the kidney of progeroid Ercc1 mutant mice.
van Thiel, B.S., van der Linden, J., Ridwan, Y., Garrelds, I.M., Vermeij, M., Clahsen-van Groningen, M.C., Qadri, F., Alenina, N., Bader, M., Roks, A.J.M., Danser, A.H.J., Essers, J. and van der Pluijm, I.
International Journal of Molecular Sciences 22
(22): 12433.
18 November 2021
Anti-inflammatory role of Gpnmb in adipose tissue of mice.
Nickl, B., Qadri, F. and Bader, M.
Scientific Reports 11
(1): 19614.
4 October 2021
Kpna6 deficiency causes infertility in male mice by disrupting spermatogenesis.
Liu, N., Qadri, F., Busch, H., Huegel, S., Sihn, G., Chuykin, I., Hartmann, E., Bader, M. and Rother, F.
Development 148
(19): dev.198374.
1 October 2021
Alamandine but not angiotensin-(1-7) produces cardiovascular effects at the rostral insular cortex.
Marins, F.R., Oliveira, A.C., Qadri, F., Motta-Santos, D., Alenina, N., Bader, M., Fontes, M.A.P. and Souza Santos, R.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 321
(3): R513-R521.
10 September 2021
Hemodynamic phenotyping of transgenic rats with ubiquitous expression of an angiotensin-(1-7)-producing fusion protein.
Alves, D.T., Mendes, L.F., Sampaio, W.O., Coimbra-Campos, L.M.C., Vieira, M.A.R., Ferreira, A.J., Martins, A.S., Popova, E., Todiras, M., Qadri, F., Alenina, N., Bader, M., Santos, R.A.S. and Campagnole-Santos, M.J.
Clinical Science 135
(18): 2197-2216.
8 September 2021
Cortisol dose-dependently impairs migration and tube-like formation in a trophoblast cell line and modulates inflammatory and angiogenic genes.
Húngaro, T.G.R, Gregnani, M.F., Alves-Silva, T., Herse, F., Alenina, N., Bader, M. and Araújo, R.C.
Biomedicines 9
(8): 980.
August 2021
The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule.
Figueiredo, M., Daryadel, A., Sihn, G., Müller, D.N., Popova, E., Rouselle, A., Nguyen, G., Bader, M. and Wagner, C.A.
Pflugers Archiv 473
: 1229-1246.
August 2021
Community-wide experimental evaluation of the PROSS stability-design method.
Peleg, Y., Vincentelli, R., Collins, B.M., Chen, K.E., Livingstone, E.K., Weeratunga, S., Leneva, N., Guo, Q., Remans, K., Perez, K., Bjerga, G.E.K., Larsen, Ø., Vaněk, O., Skořepa, O., Jacquemin, S., Poterszman, A., Kjaer, S., Christodoulou, E., Albeck, S., Dym, O., Ainbinder, E., Unger, T., Schuetz, A., Matthes, S., Bader, M., de Marco, A., Storici, P., Semrau, M.S., Stolt-Bergner, P., Aigner, C., Suppmann, S., Goldenzweig, A. and Fleishman, S.J.
Journal of Molecular Biology 433
(13): 166964.
25 June 2021
Increased angiotensin II formation in the brain modulates cardiovascular homeostasis and erythropoiesis.
Rodrigues, A.F., Todiras, M., Qadri, F., Campagnole-Santos, M.J., Alenina, N. and Bader, M.
Clinical Science 135
(11): 1353-1367.
2 June 2021
Phenylalanine-hydroxylase contributes to serotonin synthesis in mice.
Mordhorst, A., Dhandapani, P., Matthes, S., Mosienko, V., Rothe, M., Todiras, M., Self, J., Schunck, W.H., Schütz, A., Bader, M. and Alenina, N.
FASEB Journal 35
(6): e21648.
June 2021
Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy.
Ku, M.C., Kober, F., Lai, Y.C., Pohlmann, A., Qadri, F., Bader, M., Carrier, L. and Niendorf, T.
Journal of Cardiovascular Magnetic Resonance 23
(1): 63.
31 May 2021
AT1 and AT2 receptor knockout changed osteonectin and bone density in mice in periodontal inflammation experimental model.
Lima, M.L.S., Medeiros, C.A.C.X., Guerra, G.C.B., Santos, R., Bader, M., Pirih, F.Q., Araújo Júnior, R.F., Chan, A.B., Cruz, L.J., Brito, G.A.C., Leitão, R.F.C., Silveira, EJ.D., Garcia, V.B., Martins, A.A. and Araújo, A.A.
International Journal of Molecular Sciences 22
(10): 5217.
14 May 2021
Agonistic autoantibodies against β2-adrenergic receptor influence retinal microcirculation in glaucoma suspects and patients.
Hohberger, B., Hosari, S., Wallukat, G., Kunze, R., Krebs, J., Müller, M., Hennig, T., Lämmer, R., Horn, F., Muñoz, L.E., Herrmann, M. and Mardin, C.
PLoS ONE 16
(5): e0249202.
7 May 2021
Agonistic β2-adrenergic receptor autoantibodies characterize the aqueous humor of patients with primary and secondary open-angle glaucoma.
Hohberger, B., Wörn, M., Lämmer, R., Mahajan, A., Mardin, C., Schötzer-Schrehardt, U., Kunze, R., Herrmann, M. and Wallukat, G.
Frontiers in Immunology 12
: 550236.
5 May 2021
Alterations in BDNF protein concentrations in the hippocampus do not explain the pro-neurogenic effect of citalopram on adult neurogenesis.
Petermann, M., Kronenberg, G., Mosienko, V., Bader, M., Alenina, N., Hellweg, R. and Klempin, F.
Pharmacopsychiatry 54
(3): 101-105.
May 2021
Knockout of aminopeptidase A in mice causes functional alterations and morphological glomerular basement membrane changes in the kidneys.
Marahrens, B., Schulze, A., Wysocki, J., Lin, M.H., Ye, M., Kanwar, Y.S., Bader, M., Velez, J.C.Q., Miner, J.H. and Batlle, D.
Kidney International 99
(4): 900-913.
April 2021
Dorsal raphe serotonin neurotransmission is required for the expression of nursing behavior and for pup survival.
Muzerelle, A., Soiza-Reilly, M., Hainer, C., Ruet, P.L., Lesch, K.P., Bader, M., Alenina, N., Scotto-Lomassese, S. and Gaspar, P.
Scientific Reports 11
(1): 6004.
16 March 2021
Genetic deletion of trace-amine associated receptor 9 (TAAR9) in rats leads to decreased blood cholesterol levels.
Murtazina, R.Z., Zhukov, I.S., Korenkova, O.M., Popova, E.A., Kuvarzin, S. R., Efimova, E.V., Kubarskaya, L.G., Batotsyrenova, E.G., Zolotoverkhaya, E.A., Vaganova, A.N., Apryatin, S.A., Alenina, N.V. and Gainetdinov, R.R.
International Journal of Molecular Sciences 22
(6): 2942.
2 March 2021
Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting.
Zanders, L., Kny, M., Hahn, A., Schmidt, S., Wundersitz, S., Todiras, M., Lahmann, I., Bandyopadhyay, A., Wollersheim, T., Kaderali, L., Luft, F.C., Birchmeier, C., Weber-Carstens, S. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 13
(1): 713-727.
February 2021
Intrauterine exposure to diabetic milieu does not induce diabetes and obesity in male adulthood in a novel rat model.
Schütte, T., Kedziora, S.M., Haase, N., Herse, F., Busjahn, A., Birukov, A., Alenina, N., Müller, D.N., Bader, M., Schupp, M., Dechend, R., Kräker, K. and Golic, M.
Hypertension 77
(1): 202-215.
January 2021
Relevance of Angiotensin-(1-7) and its receptor Mas in pneumonia caused by Influenza virus and post-influenza pneumococcal infection.
Melo, E.M., Del Sarto, J., Vago, J.P., Tavares, L.P., Rago, F., Gonçalves, A.P.F., Machado, M.G., Aranda-Pardos, I., Valiate, B.V.S., Cassali, G.D., Pinho, V., Sousa, L.P., A-Gonzalez, N., Campagnole-Santos, M.J., Bader, M., Santos, R.A.S., Machado, A.V., Ludwig, S. and Teixeira, M.M.
Pharmacological Research 163
: 105292.
January 2021
Paternal exercise protects against liver steatosis in the male offspring of mice submitted to high fat diet.
Batista, R.O., Budu, A., Alves-Silva, T., Arakaki, A.M., Gregnani, M.F.S., Rodrigues Húngaro, T.G., Burgos-Silva, M., Wasinski, F., Lanzoni, V.P., Camara, N.O.S., Oyama, L.M., Bader, M. and Araújo, R.C.
Life Sciences 263
: 118583.
15 December 2020
Angiotensin-(1-7) prevents lipopolysaccharide-induced autophagy via the Mas receptor in skeletal muscle.
Rivera, J.C., Abrigo, J., Tacchi, F., Simon, F., Brandan, E., Santos, R.A., Bader, M., Chiong, M. and Cabello-Verrugio, C.
International Journal of Molecular Sciences 21
(24): 9344.
8 December 2020
The effect of ageing and cerebral serotonin deficit on the activity of cytochrome P450 2D (CYP2D) in the brain and liver of male rats.
Haduch, A., Pukło, R., Alenina, N., Nikiforuk, A., Popik, P., Bader, M. and Daniel, W.A.
Neurochemistry International 141
: 104884.
December 2020
ACE2 - das missbrauchte Multitalent [ACE2 - the hijacked all-rounder].
Bader, M.
Nephrologe 15
(6): 375-380.
November 2020
Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy.
Ni, J., Yang, F., Huang, X.R., Meng, J., Chen, J., Bader, M., Penninger, J.M., Fung, E., Yu, X.Q. and Lan, H.Y.
Journal of Cellular and Molecular Medicine 24
(22): 13093-13103.
November 2020
Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes.
Kräker, K., Herse, F., Golic, M., Reichhart, N., Crespo-Garcia, S., Straß, O., Grune, J., Kintscher, U., Ebrahim, M., Bader, M., Alenina, N., Heuser, A., Luft, F.C., Müller, D.N., Dechend, R. and Haase, N.
Scientific Reports 10
(1): 14061.
20 August 2020
Importin α3 regulates chronic pain pathways in peripheral sensory neurons.
Marvaldi, L., Panayotis, N., Alber, S., Dagan, S.Y., Okladnikov, N., Koppel, I., Di Pizio, A., Song, D.A., Tzur, Y., Terenzio, M., Rishal, I., Gordon, D., Rother, F., Hartmann, E., Bader, M. and Fainzilber, M.
Science 369
(6505): 842-846.
14 August 2020
Angiotensin‐II receptor type Ia does not contribute to cardiac atrophy following high‐thoracic spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S. and Bader, M.
Experimental Physiology 105
(8): 1316-1325.
1 August 2020
Age-related shift in LTD is dependent on neuronal adenosine A(2A) receptors interplay with mGluR5 and NMDA receptors.
Temido-Ferreira, M., Ferreira, D.G., Batalha, V.L., Marques-Morgado, I., Coelho, J.E., Pereira, P., Gomes, R., Pinto, A., Carvalho, S., Canas, P.M., Cuvelier, L., Buée-Scherrer, V., Faivre, E., Baqi, Y., Müller, C.E., Pimentel, J., Schiffmann, S.N., Buée, L., Bader, M., Outeiro, T.F., Blum, D., Cunha, R.A., Marie, H., Pousinha, P.A. and Lopes, L.V.
Molecular Psychiatry 25
(8): 1876-1900.
August 2020
B(1) and B(2) kinin receptor blockade improves psoriasis-like disease.
da Silva Soley, B., Silva, L.M., Mendes, D.A.G.B., Báfica, A., Pesquero, J.B., Bader, M., Witherden, D.A., Havran, W.L., Calixto, J.B., Otuki, M.F. and Cabrini, D.A.
British Journal of Pharmacology 177
(15): 3535-3551.
August 2020
Genetic deletion of the angiotensin-(1-7) receptor mas leads to alterations in gut villi length modulating TLR4/PI3K/AKT and produces microbiome dysbiosis.
Oliveira, L.P., Guimarães, V.H.D., Oliveira, J.R., Guimarães, A.L.S., de Paula, A.M.B., Bader, M., dos Santos, R.A.S. and Santos, S.H.S.
Neuropeptides 82
: 102056.
August 2020
Phosphodiesterase 3A and arterial hypertension.
Ercu, M., Markó, L., Schächterle, C., Tsvetkov, D., Cui, Y., Maghsodi, S., Bartolomaeus, T.U.P., Maass, P.G., Zühlke, K., Gregersen, N., Hübner, N., Hodge, R., Mühl, A., Pohl, B., Molé-Illas, R., Geelhaar, A., Walter, S., Napieczynska, H., Schelenz, S., Taube, M., Heuser, A., Anistan, Y.M., Qadri, F., Todiras, M., Plehm, R., Popova, E., Langanki, R., Eichhorst, J., Lehmann, M., Wiesner, B., Russwurm, M., Forslund, S.K., Kamer, I., Müller, D.N., Gollasch, M., Aydin, A., Bähring, S., Bader, M., Luft, F.C. and Klussmann, E.
Circulation 142
(2): 133-149.
14 July 2020
The absence of serotonin in the brain alters acute stress responsiveness by interfering with the genomic function of the glucocorticoid receptors.
Sbrini, G., Brivio, P., Peeva, P.M., Todiras, M., Bader, M., Alenina, N. and Calabrese, F.
Frontiers in Cellular Neuroscience 14
: 128.
1 June 2020
CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development.
Aherrahrou, R., Kulle, A.E., Alenina, N., Werner, R., Vens-Cappell, S., Bader, M., Schunkert, H., Erdmann, J. and Aherrahrou, Z.
Scientific Reports 10
(1): 8792.
29 May 2020
Angiotensin-converting enzyme inhibitor protects against cisplatin nephrotoxicity by modulating kinin B1 receptor expression and aminopeptidase P activity in mice.
Estrela, G.R., Wasinski, F., Gregnani, M.F., Freitas-Lima, L.C., Arruda, A.C., Morais, R.L., Malheiros, D.M.A.C., Camara, N.O.S., Pesquero, J.B., Bader, M., Barros, C.C. and Araújo, R.C.
Frontiers in Molecular Biosciences 7
: 96.
20 May 2020
Short-term western diet aggravates non-alcoholic fatty liver disease (NAFLD) with portal hypertension in TGR(mREN2)27 rats.
Cremonese, C., Schierwagen, R., Uschner, F.E., Torres, S., Tyc, O., Ortiz, C., Schulz, M., Queck, A., Kristiansen, G., Bader, M., Sauerbruch, T., Weiskirchen, R., Walther, T., Trebicka, J. and Klein, S.
International Journal of Molecular Sciences 21
(9): 3308.
1 May 2020
Cellular importin-α3 expression dynamics in the lung regulate antiviral response pathways against influenza a virus infection.
Thiele, S., Stanelle-Bertram, S., Beck, S., Kouassi, N., Zickler, M., Müller, M., Tuku, B., Resa-Infante, P., van Riel, D., Alawi, M., Günther, T., Rother, F., Hügel, S., Reimering, S., McHardy, A., Grundhoff, A., Brune, W., Osterhaus, A., Bader, M., Hartmann, E. and Gabriel, G.
Cell Reports 31
(3): 107549.
21 April 2020
3-amino-1,2,4-triazole induces quick and strong fat loss in mice with high fat-induced metabolic syndrome.
Nunes-Souza, V., Dias-Júnior, N.M., Eleutério-Silva, M.A., Ferreira-Neves, V.P., Moura, F.A., Alenina, N., Bader, M. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2020
: 3025361.
13 April 2020
Angiotensin-(1-7) receptor Mas deficiency does not exacerbate cardiac atrophy following high-level spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S., Alenina, N. and Bader, M.
Frontiers in Physiology 11
: 203.
12 March 2020
Angiotensin-(1-7) induces beige fat thermogenesis through the Mas receptor.
Vargas-Castillo, A., Tobon-Cornejo, S., Del Valle-Mondragon, L., Torre-Villalvazo, I., Schcolnik-Cabrera, A., Guevara-Cruz, M., Pichardo-Ontiveros, E., Fuentes-Romero, R., Bader, M., Alenina, N., Vidal-Puig, A., Hong, E., Torres, N. and Tovar, A.R.
Metabolism 103
: 154048.
February 2020
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M., Pablo-Tortola, C., Todiras, M., Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M., Jarosch, E., Sommer, T., Bröker, B.M., Felix, S.B., Scheidereit, C., Weber-Carstens, S., Butter, C., Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 11
(1): 103-119.
February 2020
The activity of the STriatal-Enriched protein tyrosine Phosphatase (STEP) in neuronal cells is modulated by adenosine A(2A) receptor.
Mallozzi, C., Pepponi, R., Visentin, S., Chiodi, V., Lombroso, P.J., Bader, M., Popoli, P. and Domenici, M.R.
Journal of Neurochemistry 152
(3): 284-298.
February 2020
Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L., Peeva, P., Ramos-Prats, A., Alenina, N., Winter, Y. and Rivalan, M.
Behavioural Brain Research 377
: 112188.
13 January 2020
Ang II (angiotensin II) conversion to angiotensin-(1-7) in the circulation is POP (prolyloligopeptidase)-dependent and ACE2 (angiotensin-converting enzyme 2)-independent.
Serfozo, P., Wysocki, J., Gulua, G., Schulze, A., Ye, M., Liu, P., Jin, J., Bader, M., Myöhänen, T., García-Horsman, J.A. and Batlle, D.
Hypertension 75
(1): 173-182.
January 2020
Angiotensin II type 2 receptor mediates high fat diet-induced cardiomyocyte hypertrophy and hypercholesterolemia.
Lima, V.M., Lino, C.A., Senger, N., de Oliveira Silva, T., Fonseca, R.I.B., Bader, M., Santos, R.A.S., Júnior, JD., Barreto-Chaves, M.L.M. and Diniz, G.P.
Molecular and Cellular Endocrinology 498
: 110576.
1 December 2019
The role of receptor MAS in microglia-driven retinal vascular development.
Foulquier, S., Caolo, V., Swennen, G., Milanova, I., Reinhold, S., Recarti, C., Alenina, N., Bader, M., Steckelings, U M., Vanmierlo, T., Post, M.J., Jones, E.A., van Oostenbrugge, R.J. and Unger, T.
Angiogenesis 22
(4): 481-189.
November 2019
Increased ethanol consumption and locomotion develop upon ethanol deprivation in rats overexpressing the adenosine A(2A) receptor.
Zaniewska, M., Gawliński, D., Wyczesana, M., Nowak, E., Kula, K., Maciów-Głąb, M., Jastrzębska, J., Sadakierska-Chudy, A., Bader, M. and Fuxe, K.
Neuroscience 418
: 133-148.
15 October 2019
Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J., Neukam, M., Tattikota, S.G., Qadri, F., Puchkov, D., Willmes, D.M., Wurmsee, S., Geisberger, S., Dechend, R., Raile, K., Kurth, T., Nguyen, G., Poy, M.N., Solimena, M., Muller, D.N. and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116
(40): 19983-19988.
1 October 2019
Endothelial B2-receptor overexpression as an alternative animal model for hereditary angioedema.
Lopes Veronez, C., Maghsodi, S., Todiras, M., Popova, E., Rodrigues, A.F., Qadri, F., Pesquero, J.B. and Bader, M.
Allergy 74
(10): 1998-2002.
October 2019
Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells.
Guimarães, P.B., da Silva, R.F., Hoff, C.C., Fernandes, L., Nakaie, C.R., Chagas, J.R., Karaoglanovic Carmona, A., Bader, M. and Pesquero, J.B.
Inflammation Research 68
(10): 845-855.
October 2019
Targeted genomic integration of EGFP under tubulin beta 3 class III promoter and mEos2 under tryptophan hydroxylase 2 promoter does not produce sufficient levels of reporter gene expression.
Menzorov, A.G., Orishchenko, K.E., Fishman, V.S., Shevtsova, A.A., Mungalov, R.V., Pristyazhnyuk, I.E., Kizilova, E.A., Matveeva, N.M., Alenina, N., Bader, M., Rubtsov, N.B. and Serov, O.L.
Journal of Cellular Biochemistry 120
(10): 17208-17218.
October 2019
Serotonin synthesis protects the mouse colonic crypt from DNA damage and colorectal tumorigenesis.
Sakita, J.Y., Bader, M., Santos, E.S., Garcia, S.B., Minto, S.B., Alenina, N., Brunaldi, M.O., Carvalho, M.C., Vidotto, T., Gasparotto, B., Martins, R.B., Silva, W.A., Brandão, M.L., Leite, C.A., Cunha, F.Q., Karsenty, G., Squire, J.A., Uyemura, S.A. and Kannen, V.
Journal of Pathology 249
(1): 102-113.
September 2019
Thimet oligopeptidase (EC 3.4.24.15) key functions suggested by knockout mice phenotype characterization.
Santos, N.B.D., Franco, R.D., Camarini, R., Munhoz, C.D., Eichler, R.A.S., Gewehr, M.C.F., Reckziegel, P., Llanos, R.P., Dale, C.S., da Silva, V.R.O., Borges, V.F., Lima, B.H.F., Cunha, F.Q., Visniauskas, B., Chagas, J.R., Tufik, S., Peres, F.F., Abilio, V.C., Florio, J.C., Iwai, L.K., Rioli, V., Presoto, B.C., Guimaraes, A.O., Pesquero, J.B., Bader, M., Castro, L.M. and Ferro, E.S.
Biomolecules 9
(8): 382.
19 August 2019
TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor.
Klein, S., Kleine, C.E., Pieper, A., Granzow, M., Gautsch, S., Himmit, M., Kahrmann, K., Schierwagen, R., Uschner, F.E., Magdaleno, F., Naoum, M.E., Kristiansen, Glen, Walther, T., Bader, M., Sauerbruch, T. and Trebicka, J.
Scientific Reports 9
(1): 11598.
12 August 2019
hnRNP-K targets open chromatin in mouse embryonic stem cells in concert with multiple regulators.
Bakhmet, E.I., Nazarov, I.B., Gazizova, A.R., Vorobyeva, N.E., Kuzmin, A.A., Gordeev, M.N., Sinenko, S.A., Aksenov, N. D., Artamonova, T.O., Khodorkovskii, M.A., Alenina, N., Onichtchouk, D., Wu, G., Schöler, H.R. and Tomilin, A.N.
Stem Cells 37
(8): 1018-1029.
August 2019
Targeted manipulation of brain serotonin: RNAi-mediated knockdown of tryptophan hydroxylase 2 in rats.
Matthes, S., Mosienko, V., Popova, E., Rivalan, M., Bader, M. and Alenina, N.
ACS Chemical Neuroscience 10
(7): 3207-3217.
17 July 2019
Nephropathy in hypertensive animals is linked to M2 macrophages and increased expression of the YM1/Chi3l3 protein.
Cavalcante, P.A.M., Alenina, N., Budu, A., Freitas-Lima, L.C., Alves-Silva, T., Agudelo, J.S.H., Qadri, F., Camara, N.O.S., Bader, M. and Araújo, R.C.
Mediators of Inflammation 2019
: 9086758.
10 July 2019
Priming of LTP in amygdala and hippocampus by prior paired pulse facilitation paradigm in mice lacking brain serotonin.
Gebhardt, C., Mosienko, V., Alenina, N. and Albrecht, D.
Hippocampus 29
(7): 610-618.
July 2019
The antiobese effect of AT1 receptor blockade is augmented in mice lacking Mas.
Dapper, C., Schuster, F., Stölting, I., Vogt, F., Castro e Souza, L.A., Alenina, N., Bader, M. and Raasch, W.
Naunyn-Schmiedeberg's Archives of Pharmacology 392
(7): 865-877.
July 2019
Urinary renin in patients and mice with diabetic kidney disease.
Tang, J., Wysocki, J., Ye, M., Vallés, P.G., Rein, J., Shirazi, M., Bader, M., Gomez, R.A., Sequeira-Lopez, M.L.S., Afkarian, M. and Batlle, D.
Hypertension 74
(1): 83-94.
July 2019
Systemic outcomes of (Pyr(1))-apelin-13 infusion at mid-late pregnancy in a rat model with preeclamptic features.
Yamaleyeva, L.M., Brosnihan, K.B., Elsangeedy, E., McGee, C., Shi, S., Caudell, D., Miller, C., Varagic, J., Bader, M., Dechend, R. and Shaltout, H.A.
Scientific Reports 9
(1): 8579.
12 June 2019
ACE2 in brain physiology and pathophysiology: evidence from transgenic animal models.
Alenina, N. and Bader, M.
Neurochemical Research 44
(6): 1323-1329.
June 2019
Lack of brain serotonin affects feeding and differentiation of newborn cells in the adult hypothalamus.
van Lingen, M., Sidorova, M., Alenina, N. and Klempin, F.
Frontiers in Cell and Developmental Biology 7
: 65.
April 2019
Serotonin deficiency increases context-dependent fear learning through modulation of hippocampal activity.
Waider, J., Popp, S., Mlinar, B., Montalbano, A., Bonfiglio, F., Aboagye, B., Thuy, E., Kern, R., Thiel, C., Araragi, N., Svirin, E., Schmitt-Böhrer, A.G., Corradetti, R., Lowry, C.A. and Lesch, K.P.
Frontiers in Neuroscience 13
: 245.
April 2019
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Farrelly, L.A., Thompson, R.E., Zhao, S., Lepack, A.E., Lyu, Y., Bhanu, N.V., Zhang, B., Loh, Y.H.E., Ramakrishnan, A., Vadodaria, K.C., Heard, K.J., Erikson, G., Nakadai, T., Bastle, R.M., Lukasak, B.J., Zebroski, H., Alenina, N., Bader, M., Berton, O., Roeder, R.G., Molina, H., Gage, F.H., Shen, L., Garcia, B.A., Li, H., Muir, T.W. and Maze, I.
Nature 567
(7749): 535-539.
28 March 2019
Angiotensin-(1-7) receptor Mas in hemodynamic and thermoregulatory dysfunction after high-level spinal cord injury in mice: a pilot study.
Järve, A., Todiras, M., Kny, M., Fischer, F.I., Kraemer, J.F., Wessel, N., Plehm, R., Fielitz, J., Alenina, N. and Bader, M.
Frontiers in Physiology 9
: 1930.
January 2019
Distinct roles of angiotensin receptors in autonomic dysreflexia following high-level spinal cord injury in mice.
Järve, A., Todiras, M., Lian, X, Filippelli-Silva, R., Qadri, F., Martin, R.P., Gollasch, M. and Bader, M.
Experimental Neurology 311
: 173-181.
January 2019
Genetic deletion of the alamandine receptor MrgD leads to dilated cardiomyopathy in mice.
Oliveira, A.C., Melo, M.B., Motta-Santos, D., Peluso, A.A., Souza-Neto, F., da Silva, R.F., Almeida, J.F.Q., Canta, G., Reis, A.M., Goncalves, G., Cerri, G.G., Coutinho, D., de Jesus, I.C.G., Guatimosim, S., Linhares, N.D., Alenina, N., Bader, M., Campagnole-Santos, M.J. and Santos, R.A.S.
American Journal of Physiology Heart and Circulatory Physiology 316
(1): H123-H133.
January 2019
Importin α5 regulates anxiety through MeCP2 and sphingosine kinase 1.
Panayotis, N., Sheinin, A., Dagan, S.Y., Tsoory, M.M., Rother, F., Vadhvani, M., Meshcheriakova, A., Koley, S., Marvaldi, L., Song, D.A., Reuveny, E., Eickholt, B.J., Hartmann, E., Bader, M., Michaelevski, I. and Fainzilber, M.
Cell Reports 25
(11): 3169-3179.
11 December 2018
Transfer of synthetic human chromosome into human induced pluripotent stem cells for biomedical applications.
Sinenko, S.A., Skvortsova, E.V., Liskovykh, M.A., Ponomartsev, S.V., Kuzmin, A.A., Khudiakov, A.A., Malashicheva, A.B., Alenina, N., Larionov, V., Kouprina, N. and Tomilin, A.N.
Cells 7
(12): 261.
8 December 2018
Exon skipping in a Dysf-missense mutant mouse model.
Malcher, J., Heidt, L., Goyenvalle, A., Escobar, H., Marg, A., Beley, C., Benchaouir, R., Bader, M., Spuler, S., García, L. and Schöwel, V.
Molecular Therapy - Nucleic Acids 13
: 198-207.
7 December 2018
Apelinergic system in the kidney: implications for diabetic kidney disease.
Müller, T., Kalea, A.Z., Marquez, A., Hsieh, I., Haque, S., Ye, M., Wysocki, J., Bader, M. and Batlle, D.
Physiological Reports 6
(23): e13939.
December 2018
Brain serotonin critically contributes to the biological effects of electroconvulsive seizures.
Kronenberg, G., Petermann, M., Dormann, C., Bader, M., Gass, P., Hellweg, R. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 268
(8): 861-864.
December 2018
Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: Comparison to chronic phencyclidine and MK-801.
Hámor, P.U., Šírová, J., Páleníček, T., Zaniewska, M., Bubeníková-Valešová, V. and Schwendt, M.
Pharmacology Biochemistry and Behavior 175
: 89-100.
December 2018
Chronic overexpression of bradykinin in kidney causes polyuria and cardiac hypertrophy.
Barros, C.C., Schadock, I., Sihn, G., Rother, F., Xu, P., Popova, E., Lapidus, I., Plehm, R., Heuser, A., Todiras, M., Bachmann, S., Alenina, N., Araujo, R.C., Pesquero, J.B. and Bader, M.
Frontiers in Medicine 5
: 338.
December 2018
TRPM8 activation via 3-iodothyronamine blunts VEGF-induced transactivation of TRPV1 in human uveal melanoma cells.
Walcher, L., Budde, C., Böhm, A., Reinach, P.S., Dhandapani, P., Ljubojevic, N., Schweiger, M.W., von der Waydbrink, H., Reimers, I., Köhrle, J. and Mergler, S.
Frontiers in Pharmacology 9
: 1234.
13 November 2018
Bradykinin B2 receptor is essential to running-induced cell proliferation in the adult mouse hippocampus.
Wasinski, F., Oliveira Batista, R., Bader, M., Araujo, R.C. and Klempin, F.
Brain Structure & Function 223
(8): 3901-3907.
November 2018
The angiotensin II type 2 receptors protect renal tubule mitochondria in early stages of diabetes mellitus.
Micakovic, T., Papagiannarou, S., Clark, E., Kuzay, Y., Abramovic, K., Peters, J., Sticht, C., Volk, N., Fleming, T., Nawroth, P., Hammes, H.P., Alenina, N., Gröne, H.J. and Hoffmann, S.C.
Kidney International 94
(5): 937-950.
November 2018
TPH2 deficiency influences neuroplastic mechanisms and alters the response to an acute stress in a sex specific manner.
Brivio, P., Sbrini, G., Peeva, P., Todiras, M., Bader, M., Alenina, N. and Calabrese, F.
Frontiers in Molecular Neuroscience 11
: 389.
30 October 2018
Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response.
Klempin, F., Mosienko, V., Matthes, S., Villela, D.C., Todiras, M., Penninger, J.M., Bader, M., Santos, R.A.S. and Alenina, N.
Cellular and Molecular Life Sciences 75
(19): 3625-3634.
October 2018
Genetic deletion of the Angiotensin-(1-7) receptor Mas leads a reduced ovulatory rate.
Honorato-Sampaio, K., Ferreira Andrade, R., Bader, M., de Souza Martins, A., Souza Santos, R.A. and Reis, A.M.
Peptides 107
: 83-88.
September 2018
Neuronal adenosine A(2A) receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease.
Domenici, M.R., Chiodi, V., Averna, M., Armida, M., Pèzzola, A., Pepponi, R., Ferrante, A., Bader, M., Fuxe, K. and Popoli, P.
Purinergic Signalling 14
(3): 235-243.
September 2018
Role of 3-acetyl-11-keto-beta-boswellic acid in counteracting LPS-induced neuroinflammation via modulation of miRNA-155.
Sayed, A.S., Gomaa, I.E.O., Bader, M. and El Sayed, N.S.E.D.
Molecular Neurobiology 55
(7): 5798-5808.
July 2018
ATP6AP2 over-expression causes morphological alterations in the hippocampus and in hippocampus-related behaviour.
Bracke, A., Schäfer, S., von Bohlen und Halbach, V., Klempin, F., Bente, K., Bracke, K., Staar, D., van den Brandt, J., Harzsch, S., Bader, M., Wenzel, U.O., Peters, J. and von Bohlen und Halbach, O.
Brain Structure & Function 223
(5): 2287-2302.
June 2018
Alamandine acts via MrgD to induce AMPK/NO activation against Ang II hypertrophy in cardiomyocytes.
de Jesus, I.C.G., Scalzo, S., Alves, F., Marques, K., Rocha-Resende, C., Bader, M., Santos, R.A.S. and Guatimosim, S.
American Journal of Physiology Cell Physiology 314
(6): C702-C711.
June 2018
Cardioprotective effect of thyroid hormone is mediated by AT2 receptor and involves nitric oxide production via Akt activation in mice.
da Silva, I.B., Gomes, D.A., Alenina, N., Bader, M., dos Santos, R.A. and Barreto-Chaves, M.L.M.
Heart and Vessels 33
(6): 671-681.
June 2018
Cystathionine γ-lyase-produced hydrogen sulfide controls endothelial NO bioavailability and blood pressure.
Szijártó, I.A., Markó, L., Filipovic, M.R., Miljkovic, J.L., Tabeling, C., Tsvetkov, D., Wang, N., Rabelo, L.A., Witzenrath, M., Diedrich, A., Tank, J., Akahoshi, N., Kamata, S., Ishii, I. and Gollasch, M.
Hypertension 71
(6): 1210-1217.
June 2018
Development of obesity can be prevented in rats by chronic icv infusions of AngII but less by Ang(1-7).
Winkler, M., Bader, M., Schuster, F., Stölting, I., Binder, S. and Raasch, W.
Pflugers Archiv 470
(6): 867-881.
June 2018
Mast cells and serotonin synthesis modulate Chagas disease in the colon: clinical and experimental evidence.
Kannen, V., Sakita, J.Y., Carneiro, Z.A., Bader, M., Alenina, N., Teixeira, R.R., de Oliveira, E.C., Brunaldi, M.O., Gasparotto, B., Sartori, D.C., Fernandes, C.R., Silva, J.S., Andrade, M.V., Silva, W.A., Uyemura, S.A. and Garcia, S.B.
Digestive Diseases and Sciences 63
(6): 1473-1484.
June 2018
Continuous blood glucose monitoring reveals enormous circadian variations in pregnant diabetic rats.
Golic, M., Kräker, K., Fischer, C., Alenina, N., Haase, N., Herse, F., Schütte, T., Henrich, W., Müller, D.N., Busjahn, A., Bader, M. and Dechend, R.
Frontiers in Endocrinology 9
: 271.
29 May 2018
Somatosensory BOLD fMRI reveals close link between salient blood pressure changes and the murine neuromatrix.
Reimann, H.M., Todiras, M., Hodge, Russ, Huelnhagen, T., Millward, J.M., Turner, R., Seeliger, E., Bader, M., Pohlmann, A. and Niendorf, T.
NeuroImage 172
: 562-574.
15 May 2018
Diabetes mellitus in pregnancy leads to growth restriction and epigenetic modification of the Srebf2 gene in rat fetuses.
Golic, M., Stojanovska, V., Bendix, I., Wehner, A., Herse, F., Haase, N., Kräker, K., Fischer, C., Alenina, N., Bader, M., Schütte, T., Schuchardt, M., van der Giet, M., Henrich, W., Muller, D.N., Felderhoff-Müser, U., Scherjon, S., Plösch, T. and Dechend, R.
Hypertension 71
(5): 911-920.
May 2018
Identification of protein phosphatase involvement in the AT(2)-receptor induced activation of endothelial nitric oxide synthase.
Peluso, A.A., Bertelsen, J.B., Andersen, K., Mortensen, T.P., Hansen, P.B., Sumners, C., Bader, M., Santos, R.A. and Steckelings, U.M.
Clinical Science 132
(7): 777-790.
6 April 2018
Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G., Uhlemann, R., Richter, N., Klempin, F., Wegner, S., Staerck, L., Wolf, S., Uckert, W., Kettenmann, H., Endres, M. and Gertz, K.
Acta Neuropathologica 135
(4): 551.
April 2018
Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
Sowa, A.S., Martin, E., Martins, I.M., Schmidt, J., Depping, R., Weber, J.J., Rother, F., Hartmann, E., Bader, M., Riess, O., Tricoire, H. and Schmidt, T.
Proceedings of the National Academy of Sciences of the United States of America 115
(11): E2624-E2633.
13 March 2018
Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.
Döhner, K., Ramos-Nascimento, A., Bialy, D., Anderson, F., Hickford-Martinez, A., Rother, F., Koithan, T., Rudolph, K., Buch, A., Prank, U., Binz, A., Hügel, S., Lebbink, R.J., Hoeben, R.C., Hartmann, E., Bader, M., Bauerfeind, R. and Sodeik, B.
PLoS Pathogens 14
(1): e1006823.
5 January 2018
Serotonin regulates prostate growth through androgen receptor modulation.
Carvalho-Dias, E., Miranda, A., Martinho, O., Mota, P., Costa, A., Nogueira-Silva, C., Moura, R.S., Alenina, N., Bader, M., Autorino, R., Lima, E. and Correia-Pinto, J.
Scientific Reports 7
(1): 15428.
13 November 2017
Cardiac morphofunctional characteristics of transgenic rats with overexpression of the bradykinin B1 receptor in the endothelium.
Levy, R.F., Serra, A.J., Antonio, E.L., dos Santos, L., Bocalini, D.S., Pesquero, J.B., Bader, M., Merino, V.F., de Oliveira, H.A., de Arruda Veiga, E.C., Silva, J.A. and Tucci, P.J.F.
Physiological Research 66
(6): 925-932.
22 September 2017
Improved cardiovascular autonomic modulation in transgenic rats expressing an Ang-(1-7)-producing fusion protein.
Dartora, D.R., Irigoyen, M.C., Casali, K.R., Moraes-Silva, I.C., Bertagnolli, M., Bader, M. and Santos, R.
Canadian Journal of Physiology and Pharmacology 95
(9): 993-998.
September 2017
Ly6C(high) monocytes oscillate in the heart during homeostasis and after myocardial infarction.
Schloss, M.J., Hilby, M., Nitz, K., Guillamat Prats, R., Ferraro, B., Leoni, G., Soehnlein, O., Kessler, T., He, W., Luckow, B., Horckmans, M., Weber, C., Duchene, J. and Steffens, S.
Arteriosclerosis Thrombosis and Vascular Biology 37
(9): 1640-1645.
September 2017
Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies.
Burghi, V., Fernández, N.C., Gándola, Y.B., Piazza, V.G., Quiroga, D.T., Guilhen Mario, E., Felix Braga, J., Bader, M., Santos, R.A.S., Dominici, F.P. and Munoz, M.C.
PLoS ONE 12
(8): e0183278.
16 August 2017
Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.
Duchene, J., Novitzky-Basso, I., Thiriot, A., Casanova-Acebes, M., Bianchini, M., Etheridge, S.L., Hub, E., Nitz, K., Artinger, K., Eller, K., Caamano, J., Ruelicke, T., Moss, P., Megens, R.T.A., von Andrian, U.H., Hidalgo, A., Weber, C. and Rot, A.
Nature Immunology 18
(7): 753-761.
July 2017
Brain renin-angiotensin system: does it exist?
van Thiel, B.S., Góes Martini, A., Te Riet, L., Severs, D., Uijl, E., Garrelds, I.M., Leijten, F.P.J., van der Pluijm, I., Essers, J., Qadri, F., Alenina, N., Bader, M., Paulis, L., Rajkovicova, R., Domenig, O., Poglitsch, M. and Danser, A.H.J.
Hypertension 69
(6): 1136-1144.
June 2017
Evidence for heterodimerization and functional interaction of the angiotensin Type 2 receptor and the receptor MAS.
Leonhardt, J., Villela, D.C., Teichmann, A., Münter, L.-M., Mayer, M.C., Mardahl, M., Kirsch, S., Namsolleck, P., Lucht, K., Benz, V., Alenina, N., Daniell, N., Horiuchi, M., Iwai, M., Multhaup, G., Schülein, R., Bader, M., Santos, R.A., Unger, T. and Steckelings, U.M.
Hypertension 69
(6): 1128-1135.
June 2017
Rodents and humans are able to detect the odour of L-Lactate.
Mosienko, V., Chang, A.J., Alenina, N., Teschemacher, A.G. and Kasparov, S.
PLoS ONE 12
(5): e0178478.
25 May 2017
Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II.
Maier, C., Schadock, I., Haber, P.K., Wysocki, J., Ye, M., Kanwar, Y., Flask, C.A., Yu, X., Hoit, B.D., Adams, G.N., Schmaier, A.H., Bader, M. and Batlle, D.
Journal of Molecular Medicine 95
(5): 473-486.
May 2017
MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells.
Estrela, G.R., Wasinski, F., Felizardo, R.J.F., Souza, L.L., Camara, N.O.S., Bader, M. and Araujo, R.C.
Molecular and Cellular Biochemistry 428
(1): 101-108.
April 2017
Elastase-2, a tissue alternative pathway for angiotensin II generation, plays a role in circulatory sympathovagal balance in mice.
Becari, C., Durand, M.T., Guimaraes, A.O., Lataro, R.M., Prado, C.M., de Oliveira, M., Candido, S.C.O., Pais, P., Ribeiro, M.S., Bader, M., Pesquero, J.B., Salgado, M.C.O. and Salgado, H.C.
Frontiers in Physiology 8
: 170.
23 March 2017
Calcineurin inhibitor cyclosporine a activates renal Na-K-Cl cotransporters via local and systemic mechanisms.
Blankenstein, K.I., Borschewski, A., Labes, R., Paliege, A., Boldt, C., McCormick, J.A., Ellison, D.H., Bader, M., Bachmann, S. and Mutig, K.
American Journal of Physiology Renal Physiology 312
(3): F489-F501.
2 March 2017
Caloric restriction is more efficient than physical exercise to protect from cisplatin nephrotoxicity via PPAR-alpha activation.
Estrela, G.R., Wasinski, F., Batista, R.O., Hiyane, M.I., Felizardo, R.J.F., Cunha, F., de Almeida, D.C., Malheiros, D.M.A.C., Camara, N.O.S., Barros, C.C., Bader, M. and Araujo, R.C.
Frontiers in Physiology 8
: 116.
2 March 2017
High aminopeptidase A activity contributes to blood pressure control in ob/ob mice by AT2 receptor-dependent mechanism.
Morais, R.L., Hilzendeger, A.M., Visniauskas, B., Todiras, M., Alenina, N., Mori, M.A., Araújo, R.C., Nakaie, C.R., Chagas, J.R., Carmona, A.., Bader, M. and Pesquero, J.B.
American Journal of Physiology Heart and Circulatory Physiology 312
(3): H437-H445.
1 March 2017
Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction.
Järve, A., Mühlstedt, S., Qadri, F., Nickl, B., Schulz, H., Hübner, N., Özcelik, C. and Bader, M.
FASEB Journal 31
(2): 556-568.
February 2017
Investigating the link between MCP-1 A-2518G, RANTES G-403A, CX3CR1 V249I and MTHFR C677T gene polymorphisms and the risk of acute myocardial infarction among Egyptians.
Hashad, I.M., Abdel Rahman, M.F., Alenina, N., Bader, M. and Gad, M.Z.
Meta Gene 11
: 181-188.
February 2017
Glucagon-producing cells are increased in Mas-deficient mice.
Felix Braga, J., Ravizzoni Dartora, D., Alenina, N., Bader, M. and Santos, R.A.S.
Endocrine Connections 6
(1): 27-32.
January 2017
The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown.
Reichhart, N., Crespo-Garcia, S., Haase, N., Golic, M., Skosyrski, S., Rübsam, A., Herrspiegel, C., Kociok, N., Alenina, N., Bader, M., Dechend, R., Strauss, O. and Joussen, A.M.
Diabetologia 60
(1): 202-211.
January 2017
Evaluation of endothelial dysfunction in vivo.
Todiras, M., Alenina, N. and Bader, M.
Methods in Molecular Biology 1527
: 355-367.
2017
Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders.
Hadar, R., Edemann-Callesen, H., Reinel, C., Wieske, F., Voget, M., Popova, E., Sohr, R., Avchalumov, Y., Priller, J., van Riesen, C., Puls, I., Bader, M. and Winter, C.
Scientific Reports 6
: 39145.
15 December 2016
Chronic allergic pulmonary inflammation is aggravated in angiotensin-(1-7) Mas receptor knockout mice.
Magalhaes, G.S., Rodrigues-Machado, M.G., Motta-Santos, D., Alenina, N., Bader, M., Santos, R.A.S., Barcelos, L.S. and Campagnole-Santos, M.J.
American Journal of Physiology Lung Cellular and Molecular Physiology 311
(6): L1141-L1148.
12 December 2016
Role of the receptor Mas in macrophage-mediated inflammation in vivo.
Hammer, A., Yang, G., Friedrich, J., Kovacs, A., Lee, D.H., Grave, K., Jörg, S., Alenina, N., Grosch, J., Winkler, J., Gold, R., Bader, M., Manzel, A., Rump, L.C., Müller, D.N., Linker, R.A. and Stegbauer, J.
Proceedings of the National Academy of Sciences of the United States of America 113
(49): 14109-14114.
6 December 2016
C-type natriuretic peptide and NPR-B signalling inhibits cardiac sympathetic neurotransmission and autonomic function.
Buttgereit, J., Shanks, J., Li, D., Hao, G., Athwal, A., Langenickel, T.H., Wright, H., da Costa Goncalves, A.C., Monti, J., Plehm, R., Popova, E., Qadri, F., Lapidus, I., Ryan, B., Özcelik, C., Paterson, D.J., Bader, M. and Herring, N.
Cardiovascular Research 112
(3): 637-644.
December 2016
Karyopherin alpha 1 regulates satellite cell proliferation and survival by modulating nuclear import.
Choo, H.J., Cutler, A., Rother, F., Bader, M. and Pavlath, G.K.
Stem Cells 34
(11): 2784-2797.
November 2016
Increased adult neurogenesis in mice with a permanent overexpression of the postsynaptic 5-HT1A receptor.
Noto, B., Klempin, F., Alenina, N., Bader, M., Fink, H. and Sander, S.E.
Neuroscience Letters 633
: 246-251.
28 October 2016
Neprilysin is a mediator of alternative renin-angiotensin-system activation in the murine and human kidney.
Domenig, O., Manzel, A., Grobe, N., Königshausen, E., Kaltenecker, C.C., Kovarik, J.J., Stegbauer, J., Gurley, S.B., van Oyen, D., Antlanger, M., Bader, M., Motta-Santos, D., Santos, R.A., Elased, K.M., Säemann, M.D., Linker, R.A. and Poglitsch, M.
Scientific Reports 6
: 33678.
21 September 2016
Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction.
Mühlstedt, S., Ghadge, S.K., Duchene, J., Qadri, F., Järve, A., Vilianovich, L., Popova, E., Pohlmann, A., Niendorf, T., Boyé, P., Özcelik, C. and Bader, M.
Journal of Molecular Medicine 94
(9): 1005-1014.
September 2016
Maternal forced swimming reduces cell proliferation in the postnatal dentate gyrus of mouse offspring.
Wasinski, F., Estrela, G.R., Arakaki, A.M., Bader, M., Alenina, N., Klempin, F. and Araújo, R.C.
Frontiers in Neuroscience 10
: 402.
29 August 2016
The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.
Batalha, V.L., Ferreira, D.G., Coelho, J.E., Valadas, J.S., Gomes, R., Temido-Ferreira, M., Shmidt, T., Baqi, Y., Buée, L., Müller, C.E., Hamdane, M., Outeiro, T.F., Bader, M., Meijsing, S.H., Sadri-Vakili, G., Blum, D. and Lopes, L.V.
Scientific Reports 6
: 31493.
11 August 2016
Demonstration of the functional impact of vasopressin signaling in the thick ascending limb by a targeted transgenic rat approach.
Mutig, K., Borowski, T., Boldt, C., Borschewski, A., Paliege, A., Popova, E., Bader, M. and Bachmann, S.
American Journal of Physiology Renal Physiology 311
(2): F411-F423.
1 August 2016
The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment.
Schloss, M.J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O. and Steffens, S.
EMBO Molecular Medicine 8
(8): 937-948.
1 August 2016
Effects of ACE2 deficiency on physical performance and physiological adaptations of cardiac and skeletal muscle to exercise.
Motta-Santos, D., Dos Santos, R.A.S., Oliveira, M., Qadri, F., Poglitsch, M., Mosienko, V., Kappes Becker, L., Campagnole-Santos, M.J., Penninger, J.M., Alenina, N. and Bader, M.
Hypertension Research 39
(7): 506-512.
July 2016
Kinin receptors in skin wound healing.
da Soley, B., Morais, R.L.T., Pesquero, J.B., Bader, M., Otuki, M.F. and Cabrini, D.A.
Journal of Dermatological Science 82
(2): 95-105.
May 2016
The brain renin-angiotensin system plays a crucial role in regulating body weight in diet-induced rat obesity.
Winkler, M., Schuchard, J., Stölting, I., Vogt, F.M., Barkhausen, J., Thorns, C., Bader, M. and Raasch, W.
British Journal of Pharmacology 173
(10): 1602-1617.
May 2016
Cardiac angiotensin-(1-12) expression and systemic hypertension in rats expressing the human angiotensinogen gene.
Ferrario, C.M., VonCannon, J.L., Jiao, Y., Ahmad, S., Bader, M., Dell'Italia, L.J., Groban, L. and Varagic, J.
American Journal of Physiology Heart and Circulatory Physiology 310
(8): H995-H1002.
15 April 2016
Increased vascular sympathetic modulation in mice with Mas receptor deficiency.
Rabello Casali, K., Ravizzoni Dartora, D., Moura, M., Bertagnolli, M., Bader, M., Haibara, A., Alenina, N., Irigoyen, M.C. and Santos, R.A.
Journal of the Renin-Angiotensin-Aldosterone System 17
(2): 1470320316643643.
13 April 2016
Genetic deletion of ACE2 induces vascular dysfunction in C57BL/6 mice: role of nitric oxide imbalance and oxidative stress.
Rabelo, L.A., Todiras, M., Nunes-Souza, V., Qadri, F., Szijártó, I.A., Gollasch, M., Penninger, J.M., Bader, M., Santos, R.A. and Alenina, N.
PLoS ONE 11
(4): e0150255.
12 April 2016
Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas.
Morales, M.G., Abrigo, J., Acuna, M.J., Santos, R.A., Bader, M., Brandan, E., Simonetta, F., Olguin, H., Cabrera, D. and Cabello-Verrugio, C.
Disease Models & Mechanisms 9
(4): 441-449.
1 April 2016
Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin.
Kronenberg, G., Mosienko, V., Gertz, K., Alenina, N., Hellweg, R. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 266
(3): 281-284.
April 2016
Identification of a novel agonist-like autoantibody in preeclamptic patients.
Velloso, E.P., Pimentel, R.L., Braga, J.F., Cabral, A.C.V., Reis, Z.S.N., Bader, M., Santos, R.A.S. and Wallukat, G.
American Journal of Hypertension 29
(3): 405-412.
March 2016
Locus coeruleus dysfunction in transgenic rats with low brain angiotensinogen.
Ogier, M., Bricca, G., Bader, M. and Bezin, L.
CNS Neuroscience & Therapeutics 22
(3): 230-237.
March 2016
Striatal adenosine-cannabinoid receptor interactions in rats overexpressing adenosine A2A receptors.
Chiodi, V., Ferrante, A., Ferraro, L., Potenza, R.L., Armida, M., Beggiato, S., Pezzola, A., Bader, M., Fuxe, K., Popoli, P. and Domenici, M.R.
Journal of Neurochemistry 136
(5): 907-917.
March 2016
Normothermic mouse functional MRI of acute focal thermostimulation for probing nociception.
Reimann, H.M., Hentschel, J., Marek, J., Huelnhagen, T., Todiras, M., Kox, S., Waiczies, S., Hodge, R., Bader, M., Pohlmann, A. and Niendorf, T.
Scientific Reports 6
: 17230.
29 January 2016
Acute hypothalamo-pituitary-adrenal axis response to LPS-induced endotoxemia: expression pattern of kinin type B1 and B2 receptors.
Qadri, F., Rimmele, F., Mallis, L., Häuser, W., Dendorfer, A., Jöhren, O., Dominiak, P., Leeb-Lundberg, L.M.F. and Bader, M.
Biological Chemistry 397
(2): 97-109.
January 2016
The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents.
Silva, C.R., Oliveira, S.M., Hoffmeister, C., Funck, V., Guerra, G.P., Trevisan, G., Tonello, R., Rossato, M.F., Pesquero, J.B., Bader, M., Oliveira, M.S., McDougall, J.J. and Ferreira, J.
Annals of the Rheumatic Diseases 75
(1): 260-268.
January 2016
Aging increases susceptibility to high fat diet-induced metabolic syndrome in C57BL/6 mice: Improvement in glycemic and lipid profile after antioxidant therapy.
Nunes-Souza, V., Cesar-Gomes, C.J., da Fonseca, L.J.S., da Silva Guedes, G., Smaniotto, S. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2016
: 1987960.
2016
CD36/sirtuin 1 axis impairment contributes to hepatic steatosis in ACE2-deficient mice.
Nunes-Souza, V., Alenina, N., Qadri, F., Penninger, J.M., Santos, R.A.S., Bader, M. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2016
: 6487509.
2016
Effect of angiotensin(1-7) on heart function in an experimental rat model of obesity.
Blanke, K., Schlegel, F., Raasch, W., Bader, M., Dähnert, I., Dhein, S. and Salameh, A.
Frontiers in Physiology 6
: 392.
21 December 2015
Exercise during pregnancy protects adult mouse offspring from diet-induced obesity.
Wasinski, F., Bacurau, R.F.P., Estrela, G.R., Klempin, F., Arakaki, A.M., Batista, R.O., Mafra, F.F.P., do Nascimento, L.F.R., Hiyane, M.I., Velloso, L.A., Camara, N.O.S. and Araujo, R.C.
Nutrition & Metabolism 12
: 56.
18 December 2015
Mas receptor deficiency exacerbates lipopolysaccharide-induced cerebral and systemic inflammation in mice.
Oliveira-Lima, O.C., Pinto, M.C.X., Duchene, J., Qadri, F., Souza, L.L., Alenina, N., Bader, M., Santos, R.A.S. and Carvalho-Tavares, J.
Immunobiology 220
(12): 1311-1321.
December 2015
Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states.
Madalli, S., Beyrau, M., Whiteford, J., Duchene, J., Singh Nandhra, I., Patel, N.S.A., Motwani, M.P., Gilroy, D.W., Thiemermann, C., Nourshargh, S. and Scotland, R.S.
Biology of Sex Differences 6
: 27.
26 November 2015
Functional changes in the uterine artery precede the hypertensive phenotype in a transgenic model of hypertensive pregnancy.
Pulgar, V.M., Yamaleyeva, L.M., Varagic, J., McGee, C., Bader, M., Dechend, R. and Brosnihan, K.B.
American Journal of Physiology Endocrinology and Metabolism 309
(9): E811-E817.
1 November 2015
Importin-α7 is involved in the formation of Ebola virus inclusion bodies but is not essential for pathogenicity in mice.
Gabriel, G., Feldmann, F., Reimer, R., Thiele, S., Fischer, M., Hartmann, E., Bader, M., Ebihara, H., Hoenen, T. and Feldmann, H.
Journal of Infectious Diseases 212
(Suppl 2): S316-S321.
1 October 2015
Multiple non-coding exons and alternative splicing in the mouse Mas protooncogene.
Alenina, N., Böhme, I., Bader, M. and Walther, T.
Gene 568
(2): 155-164.
1 September 2015
Kinin B1 and B2 receptor deficiency protects against obesity induced by a high-fat diet and improves glucose tolerance in mice.
Morais, R.L., Silva, E.D., Sales, V.M., Filippelli-Silva, R., Mori, M.A., Bader, M. and Pesquero, J.B.
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 8
: 399-407.
26 August 2015
Deletion of kinin B2 receptor alters muscle metabolism and exercise performance.
Reis, F.C.G., Haro, A.S., Bacurau, A.V.N., Hirabara, S.M., Wasinski, F., Ormanji, M.S., Moreira, J.B.N., Kiyomoto, B.H., Bertoncini, C.R.A., Brum, P.C., Curi, R., Bader, M., Bacurau, R.F.P., Pesquero, J.B. and Araújo, R.C.
PLoS ONE 10
(8): e0134844.
24 August 2015
Discovering the mechanisms underlying serotonin (5-HT)2A and 5-HT2C receptor regulation following nicotine withdrawal in rats.
Zaniewska, M., Alenina, N., Wydra, K., Fröhler, S., Kuśmider, M., McCreary, A.C., Chen, W., Bader, M. and Filip, M.
Journal of Neurochemistry 134
(4): 704-716.
August 2015
Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway.
Schuchard, J., Winkler, M., Stölting, I., Schuster, F., Vogt, F.M., Barkhausen, J., Thorns, C., Santos, R.A., Bader, M. and Raasch, W.
British Journal of Pharmacology 172
(15): 3764-3778.
August 2015
Increased aortic intimal proliferation due to MasR deletion in vitro.
Alsaadon, H., Kruzliak, P., Smardencas, A., Hayes, A., Bader, M., Angus, P., Herath, C. and Zulli, A.
International Journal of Experimental Pathology 96
(3): 183-187.
June 2015
PDE3A mutations cause autosomal dominant hypertension with brachydactyly.
Maass, P.G., Aydin, A., Luft, F.C., Schächterle, C., Weise, A., Stricker, S., Lindschau, C., Vaegler, M., Qadri, F., Toka, H.R., Schulz, H., Krawitz, P.M., Parkhomchuk, D., Hecht, J., Hollfinger, I., Wefeld-Neuenfeld, Y., Bartels-Klein, E., Mühl, A., Kann, M., Schuster, H., Chitayat, D., Bialer, M.G., Wienker, T.F., Ott, J., Rittscher, K., Liehr, T., Jordan, J., Plessis, G., Tank, J., Mai, K., Naraghi, R., Hodge, R., Hopp, M., Hattenbach, L.O., Busjahn, A., Rauch, A., Vandeput, F., Gong, M., Rüschendorf, F., Hübner, N., Haller, H., Mundlos, S., Bilginturan, N., Movsesian, M.A., Klussmann, E., Toka, O. and Bähring, S.
Nature Genetics 47
(6): 647-653.
June 2015
Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells.
Fishman, V.S., Shnayder, T.A., Orishchenko, K.E., Bader, M., Alenina, N. and Serov, O.L.
Cell Cycle 14
(8): 1188-1196.
15 April 2015
Stable maintenance of de novo assembled human artificial chromosomes in embryonic stem cells and their differentiated progeny in mice.
Liskovykh, M., Ponomartsev, S., Popova, E., Bader, M., Kouprina, N., Larionov, V., Alenina, N. and Tomilin, A.
Cell Cycle 14
(8): 1268-1273.
15 April 2015
A Grhl2-dependent gene network controls trophoblast branching morphogenesis.
Walentin, K., Hinze, C., Werth, M., Haase, N., Varma, S., Morell, R., Aue, A., Pötschke, E., Warburton, D., Qiu, A., Barasch, J., Purfürst, B., Dieterich, C., Popova, E., Bader, M., Dechend, R., Staff, A.C., Yurtdas, Z.Y., Kilic, E. and Schmidt-Ott, K.M.
Development 142
(6): 1125-1136.
15 March 2015
Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin.
Mosienko, V., Beis, D., Alenina, N. and Woehr, M.
Molecular Autism 6
: 13.
8 March 2015
Brain serotonin deficiency leads to social communication deficits in mice.
Beis, D., Holzwarth, K., Flinders, M., Mosienko, V., Bader, M., Wöhr, M. and Alenina, N.
Biology Letters 11
(3): 20150057.
March 2015
Sex dependent differences in renal angiotensinogen as an early marker of diabetic nephropathy.
de Alencar Franco Costa, D., Todiras, M., Campos, L.A., Cipolla-Neto, J., Bader, M. and Baltatu, O.C.
Acta Physiologica 213
(3): 740-746.
March 2015
Transforming growth factor type-β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular dystrophies.
Cofre, C., Acuna, M.J., Contreras, O., Morales, M.G., Riquelme, C., Bader, M., Santos, R., Cabello-Verrugio, C. and Brandan, E.
BioFactors 41
(2): 111-120.
March 2015
Vitamin D depletion aggravates hypertension and target-organ damage.
Andersen, L.B., Przybyl, L., Haase, N., von Versen-Höynck, F., Qadri, F., Jørgensen, J.S., Sorensen, G.L., Fruekilde, P., Poglitsch, M., Szijártó, I., Gollasch, M., Peters, J., Muller, D.N., Christesen, H.T. and Dechend, R.
Journal of the American Heart Association 4
(2): e001417.
February 2015
Maintenance and neuronal differentiation of chicken induced pluripotent stem-like cells.
Dai, R., Rossello, R., Chen, C.C., Kessler, J., Davison, I., Hochgeschwender, U. and Jarvis, E.D.
Stem Cells International 2014
: 182737.
9 December 2014
Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats.
Barmashenko, G., Buttgereit, J., Herring, N., Bader, M., Oezcelik, C., Manahan-Vaughan, D. and Braunewell, K.H.
Frontiers in Molecular Neuroscience 7
: 95.
1 December 2014
Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes.
Tank, J., da Costa-Goncalves, A.C., Kamer, I., Qadri, F., Ubhi, K., Rockenstein, E., Diedrich, A., Masliah, E., Gross, V. and Jordan, J.
Physiological Reports 2
(11): e12209.
26 November 2014
Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.
Markó, L., Henke, N., Park, J.K., Spallek, B., Qadri, F., Balogh, A., Apel, I.J., Oravecz-Wilson, K.I., Choi, M., Przybyl, L., Binger, K.J., Haase, N., Wilck, N., Heuser, A., Fokuhl, V., Ruland, J., Lucas, P.C., McAllister-Lucas, L.M., Luft, F.C., Dechend, R. and Müller, D.N.
Hypertension 64
(5): 1032-1039.
November 2014
Adaptive changes in serotonin metabolism preserve normal behavior in mice with reduced TPH2 activity.
Mosienko, V., Matthes, S., Hirth, N., Beis, D., Flinders, M., Bader, M., Hansson, A.C. and Alenina, N.
Neuropharmacology 85C
: 73-80.
October 2014
A student-centered approach for developing active learning: the construction of physical models as a teaching tool in medical physiology.
Rezende-Filho, F.M., Da Fonseca, L.J.S., Nunes-Souza, V., Da Silva Guedes, G. and Rabelo, L.A.
BMC Medical Education 14
: 189.
15 September 2014
A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium.
Kuppusamy, M., Caroccia, B., Stindl, J., Bandulik, S., Lenzini, L., Gioco, F., Fishman, V., Zanotti, G., Gomez-Sanchez, C., Bader, M., Warth, R. and Rossi, G.P.
Journal of Clinical Endocrinology and Metabolism 99
(9): E1765-E1773.
September 2014
Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis.
Pulgar, V.M., Yamaleyeva, L.M., Varagic, J., McGee, C.M., Bader, M., Dechend, R., Howlett, A.C. and Brosnihan, K.B.
Hypertension 64
(3): 619-625.
September 2014
Length polymorphism of the B2-VNTR minisatellite repeat of the bradykinin B2 receptor gene in healthy Russians and patients with
coronary heart disease.
Suchkova, I.O., Pavlinova, L.I., Larionova, E.E., Alenina, N.V., Solovyov, K.V., Baranova, T.V., Belotserkovskaya, E.V., Sasina, L.K., Bader, M., Denisenko, A.D., Mustafina, O.E., Khusnutdinova, E.K. and Patkin, E.L.
Molecular Biology 48
(5): 655-663.
September 2014
Distribution of non-AT(1), non-AT(2) binding of (125)I-Sarcosine(1), Isoleucine(8) angiotensin II in neurolysin knockout mouse brains.
Speth, R.C., Carrera, E.J., Bretón, C., Linares, A., Gonzalez-Reiley, L., Swindle, J.D., Santos, K.L., Schadock, I., Bader, M. and Karamyan, V.T.
PLoS ONE 9
(8): e105762.
22 August 2014
Angiotensin 1-7 reduces mortality and rupture of intracranial aneurysms in mice.
Pena Silva, R.A., Kung, D.K., Mitchell, I.J., Alenina, N., Bader, M., Santos, R.A.S., Faraci, F.M., Heistad, D.D. and Hasan, D.M.
Hypertension 64
(2): 362-368.
August 2014
Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice.
Rosendahl, A., Niemann, G., Lange, S., Ahadzadeh, E., Krebs, C., Contrepas, A., van Goor, H., Wiech, T., Bader, M., Schwake, M., Peters, J., Stahl, R., Nguyen, G. and Wenzel, U.O.
Laboratory Investigation 94
(8): 863-872.
August 2014
Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.
Schleifenbaum, J., Kassmann, M., Szijártó, I.A., Hercule, H.C., Tano, J.Y., Weinert, S., Heidenreich, M., Pathan, A.R., Anistan, Y.M., Alenina, N., Rusch, N.J., Bader, M., Jentsch, T.J. and Gollasch, M.
Circulation Research 115
(2): 263-272.
7 July 2014
Overexpression of adenosine A2A receptors in rats: effects on depression, locomotion, and anxiety.
Coelho, J.E., Alves, P., Canas, P.M., Valadas, J.S., Shmidt, T., Batalha, V.L., Ferreira, D.G., Ribeiro, J.A., Bader, M., Cunha, R.A., do Couto, F.S. and Lopes, L.V.
Frontiers in Psychiatry 5
: 67.
13 June 2014
Adenosine (A)2A receptor modulation of nicotine-induced locomotor sensitization: a pharmacological and transgenic approach.
Jastrzebska, J., Nowak, E., Smaga, I., Bystrowska, B., Frankowska, M., Bader, M., Filip, M. and Fuxe, K.
Neuropharmacology 81
: 318-326.
June 2014
Neurolysin knockout mice generation and initial phenotype characterization.
Cavalcanti, D.M.L.P., Castro, L.M., Rosa Neto, J.C., Seelaender, M., Neves, R.X., Oliveira, V., Forti, F.L., Iwai, L.K., Gozzo, F.C., Todiras, M., Schadock, I., Barros, C.C., Bader, M. and Ferro, E.S.
Journal of Biological Chemistry 289
(22): 15426-15440.
30 May 2014
Identification of importin alpha 7 specific transport cargoes using a proteomic screening approach.
Hügel, S., Depping, R., Dittmar, G., Rother, F., Cabot, R., Sury, M.D., Hartmann, E. and Bader, M.
Molecular & Cellular Proteomics 13
(5): 1286-1298.
1 May 2014
Relaxin does not improve angiotensin II-induced target-organ damage.
Haase, N., Rugor, J., Przybyl, L., Qadri, F., Müller, D.N. and Dechend, R.
PLoS ONE 9
(4): e93743.
7 April 2014
Lower expression of the Twik-related acid-sensitive K(+) channel 2 (TASK-2) gene is a hallmark of aldosterone producing adenoma causing human primary aldosteronism.
Lenzini, L., Caroccia, B., Campos, A.G., Fassina, A., Belloni, A.S., Seccia, T.M., Kuppusamy, M., Ferraro, S., Skander, G., Bader, M., Rainey, W.E. and Rossi, G.P.
Journal of Clinical Endocrinology and Metabolism 99
(4): E674-E682.
April 2014
Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5.
Lee, G.S., Simpson, C., Sun, B.H., Yao, C., Foer, D., Sullivan, B., Matthes, S., Alenina, N., Belsky, J., Bader, M. and Insogna, K.L.
Journal of Bone and Mineral Research 29
(4): 976-981.
April 2014
Receptor Mas protects mice against hypothermia and mortality induced by endotoxemia.
Souza, L.L., Duchene, J., Todiras, M., Azevedo, L.C.P., Costa-Neto, C.M., Alenina, N., Santos, R.A. and Bader, M.
Shock 41
(4): 331-336.
April 2014
Restoration of muscle strength in dystrophic muscle by Angiotensin-1-7 through inhibition of TGF-β signaling.
Acuna, M.J., Pessina, P., Olguin, H., Cabrera, D., Vio, C.P., Bader, M., Munoz-Canoves, P., Santos, R.A., Cabello-Verrugio, C. and Brandan, E.
Human Molecular Genetics 23
(5): 1237-1249.
1 March 2014
Bradykinin in health and disease: proceedings of the Bradykinin Symposium 2012, Berlin 23-24 August 2012.
Magerl, M., Bader, M., Gompel, A., Joseph, K., Kaplan, A.P., Kojda, G., Renné, T., Wirth, M., Maurer, M. and Church, M.K.
Inflammation Research 63
(3): 173-8.
March 2014
Oral administration of angiotensin-(1-7) ameliorates type 2 diabetes in rats.
Santos, S.H.S., Giani, J.F., Burghi, V., Miquet, J.G., Qadri, F., Braga, J.F., Todiras, M., Kotnik, K., Alenina, N., Dominici, F.P., Santos, R.A.S. and Bader, M.
Journal of Molecular Medicine 92
(3): 255-265.
March 2014
Avosentan is protective in hypertensive nephropathy at doses not causing fluid retention.
Baltatu, O.C., Zaugg, C.E., Schumacher, C., Louie, P., Campos, L.A. and Bader, M.
Pharmacological Research 80
: 9-13.
February 2014
Oxidative status imbalance in patients with metabolic syndrome: Role of the myeloperoxidase/hydrogen peroxide axis.
Da Fonseca, L.J.S., Nunes-Souza, V., Guedes, G.D.S., Schettino-Silva, G., Mota-Gomes, M.A. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2014
: 898501.
2014
Mas receptor deficiency is associated with worsening of lipid profile and severe hepatic steatosis in ApoE knockout mice.
Silva, A.R., Aguilar, E.C., Alvarez-Leite, J.I., da Silva, R.F., Arantes, R.M.E., Bader, M., Alenina, N., Pelli, G., Lenglet, S., Galan, K., Montecucco, F., Mach, F., Santos, S.H.S. and Santos, R.A.S.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 305
(11): R1323-R1330.
December 2013
Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen.
Kangussu, L.M., Almeida-Santos, A.F., Bader, M., Alenina, N., Fontes, M.A., Santos, R.A., Aguiar, D.C. and Campagnole-Santos, M.J.
Behavioural Brain Research 257
: 25-30.
15 November 2013
Obtainment of chimeric blastocysts of mice by methods of laser nanosurgery.
Shakhbazyan, A.K., Tarantul, V.Z., Zalessky, A.D., Ryabova, A.V., Loshchenov, V.B., Antonov, S.A., Grivennikov, I.A., Krivokharchenko, A.S., Karmenyan, A.V. and Nadtochenko, V.A.
Russian Journal of Developmental Biology 44
(6): 302-306.
November 2013
CYP2J2 overexpression protects against arrhythmia susceptibility in cardiac hypertrophy.
Westphal, C., Spallek, B., Konkel, A., Marko, L., Qadri, F., Degraff, L.M., Schubert, C., Bradbury, J.A., Regitz-Zagrosek, V., Falck, J.R., Zeldin, D.C., Müller, D.N., Schunck, W.H. and Fischer, R.
PLoS ONE 8
(8): e73490.
30 August 2013
Dual effect of chemokine CCL7/MCP-3 in the development of renal tubulointerstitial fibrosis.
Gonzalez, J., Mouttalib, S., Delage, C., Calise, D., Maoret, J.J., Pradere, J.P., Klein, J., Buffin-Meyer, B., Van der Veen, B., Charo, I.F., Heeringa, P., Duchene, J., Bascands, J.L. and Schanstra, J.P.
Biochemical and Biophysical Research Communications 438
(2): 257-263.
23 August 2013
Antinociceptive response in transgenic mice expressing rat tonin.
da Fonseca Pacheco, D., da Fonseca Pacheco, C.M., de Paula Lima, M., Bader, M., de Lima Souza, A., Pesquero, J.L., Castro Perez, A. and Duarte, I.D.G.
European Journal of Pharmacology 713
(1-3): 1-5.
5 August 2013
Mechanisms of the anti-inflammatory actions of the angiotensin type 1 receptor antagonist losartan in experimental models of arthritis.
Silveira, K.D., Coelho, F.M., Vieira, A.T., Barroso, L.C., Queiroz-Junior, C.M., Costa, V.V., Sousa, L.F.C., Oliveira, M.L., Bader, M., Silva, T.A., Santos, R.A.S., Simoes e Silva, A.C. and Teixeira, M.M.
Peptides 46
: 53-63.
August 2013
Kinin B1 receptor gene ablation affects hypothalamic CART production.
Torres, H.A.M., Motta, F.L., Sales, V.M., Batista, C., da Silva, J.M., Vignoli, T., Barnabé, G.F., Goeldner, F.O., D'Almeida, V., Bittencourt, J.C., Sinigaglia-Coimbra, R., Bader, M., Mello, L.E.A.M. and Pesquero, J.B.
Biological Chemistry 394
(7): 901-908.
July 2013
Genotype-phenotype correlation of 2q37 deletions including NPPC gene associated with skeletal malformations.
Tassano, E., Buttgereit, J., Bader, M., Lerone, M., Divizia, M.T., Bocciardi, R., Napoli, F., Pala, G., Sloan-Béna, F., Gimelli, S. and Gimelli, G.
PLoS ONE 8
(6): e66048.
21 June 2013
Beneficial effects of the activation of the Angiotensin-(1-7) MAS receptor in a murine model of adriamycin-induced nephropathy.
Silveira, K.D., Barroso, L.C., Vieira, A.T., Cisalpino, D., Lima, C.X., Bader, M., Esteves Arantes, R.M., Souza dos Santos, R.A., Simoes-e-Silva, A.C. and Teixeira, M.M.
PLoS ONE 8
(6): e66082.
7 June 2013
Short-term cardiovascular physical programme ameliorates arterial stiffness and decreases oxidative stress in women with metabolic syndrome.
Eleuterio-Silva, M.A., Sa da Fonseca, L.J., Velloso, E.P.P., da Silva Guedes, G., Sampaio, W.O., da Silva, W.F., Mota-Gomes, M.A., da Silva Lima, L.V., Santos, R.A.S. and Rabelo, L.A.
Journal of Rehabilitation Medicine 45
(6): 572-579.
June 2013
Rat model for dominant dystrophic epidermolysis bullosa: glycine substitution reduces collagen VII stability and shows gene-dosage effect.
Nyström, A., Buttgereit, J., Bader, M., Shmidt, T., Özcelik, C., Hausser, I., Bruckner-Tuderman, L. and Kern, J.S.
PLoS ONE 8
(5): e64243.
23 May 2013
Serotonin is required for exercise-induced adult hippocampal neurogenesis.
Klempin, F., Beis, D., Mosienko, V., Kempermann, G., Bader, M. and Alenina, N.
Journal of Neuroscience 33
(19): 8270-8275.
8 May 2013
Discovery and characterization of alamandine, a novel component of the renin-angiotensin system.
Lautner, R.Q., Villela, D.C., Fraga-Silva, R.A., Silva, N.C., Verano-Braga, T., Costa-Fraga, F., Jankowski, J., Jankowski, V., De Sousa, F.B., Alzamora, A.C., Soares, E.R., Barbosa, C.M., Kjeldsen, F., Oliveira, A.C., Braga, J.F., Savergnini, S.Q., Etelvino, G.M., Bastos Peluso, A.A., Passos-Silva, D.G., Ferreira, A.J., Alves, F., Martins, A.S., Raizada, M.K., Paula, R.D., Motta-Santos, D., Klempin, F., Pimenta, A.M.C., Alenina, N., Sinisterra, R.D.M., Bader, M., Campagnole-Santos, M.J. and Santos, R.A.S.
Circulation Research 112
(8): 1104-1111.
12 April 2013
Overexpression of full-length centrobin rescues limb malformation but not male fertility of the hypodactylous (hd) rats.
Liška, F., Gosele, C., Popova, E., Chylíková, B., Krenová, D., Křen, V., Bader, M., Tres, L.L., Hubner, N. and Kierszenbaum, A.L.
PLoS ONE 8
(4): e60859.
8 April 2013
Aliskiren accumulation in the kidney: no major role for binding to renin or prorenin.
Lange, S., Fraune, C., Alenina, N., Bader, M., Danser, A.H.J., Frenay, A.R., van Goor, H., Stahl, R., Nguyen, G., Schwedhelm, E. and Wenzel, U.O.
Journal of Hypertension 31
(4): 713-719.
April 2013
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models.
Cristofaro, B., Shi, Y., Faria, M., Suchting, S., Leroyer, A.S., Trindade, A., Duarte, A., Zovein, A.C., Iruela-Arispe, M.L., Nih, L.R., Kubis, N., Henrion, D., Loufrani, L., Todiras, M., Schleifenbaum, J., Gollasch, M., Zhuang, Z.W., Simons, M., Eichmann, A. and le Noble, F.
Development 140
(8): 1720-1729.
April 2013
Evidence that kinin B(2) receptor expression is upregulated by endothelial overexpression of B(1) receptors.
Rodrigues, E.S., Silva, R.F., Martin, R.P., Macedo Oliveira, S., Nakaie, C.R., Sabatini, R.A., Merino, V.F., Pesquero, J.B., Bader, M. and Shimuta, S.I.
Peptides 42
: 1-7.
April 2013
CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A., Qadri, F., Leukel, L., Yilmaz, R., Fontaine, J.F., Sihn, G., Bader, M., Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123
(3): 1343-1347.
1 March 2013
AVE 0991, a non-peptide Mas-receptor agonist, facilitates penile erection.
da Costa-Goncalves, A.C., Fraga-Silva, R.A., Leite, R. and Santos, R.A.S.
Experimental Physiology 98
(3): 850-855.
March 2013
Role of kinin B2 receptors in opioid-induced-hyperalgesia in inflammatory pain in mice.
Grastilleur, S., Mouledous, L., Bedel, J., Etcheverry, J., Bader, M., Girolami, J.P., Fourcade, O., Frances, B. and Minville, V.
Biological Chemistry 394
(3): 361-368.
March 2013
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits.
Katter, K., Geurts, A.M., Hoffmann, O., Mátés, L., Landa, V., Hiripi, L., Moreno, C., Lazar, J., Bashir, S., Zidek, V., Popova, E., Jerchow, B., Becker, K., Devaraj, A., Walter, I., Grzybowksi, M., Corbett, M., Filho, A.R., Hodges, M.R., Bader, M., Ivics, Z., Jacob, H.J., Pravenec, M., Bosze, Z., Rülicke, T. and Izsvák, Z.
FASEB Journal 27
(3): 930-941.
March 2013
Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Duerschmied, D., Suidan, G.L., Demers, M., Herr, N., Carbo, C., Brill, A., Cifuni, S.M., Mauler, M., Cicko, S., Bader, M., Idzko, M., Bode, C. and Wagner, D.D.
Blood 121
(6): 1008-1015.
7 February 2013
Novel insights into the critical role of bradykinin and the kinin B2 receptor for vascular recruitment of circulating endothelial repair-promoting mononuclear cell subsets: alterations in patients with coronary disease.
Kränkel, N., Kuschnerus, K., Müller, M., Speer, T., Mocharla, P., Madeddu, P., Bader, M., Lüscher, T.F. and Landmesser, U.
Circulation 127
(5): 594-603.
5 February 2013
Functional cross-talk between aldosterone and angiotensin-(1-7) in ventricular myocytes.
Machado de Almeida, P.W., de Freitas Lima, R., de Morais Gomes, E.R., Rocha-Resende, C., Roman-Campos, D., Gondim, A.N.S., Gavioli, M., Lara, A., Parreira, A., de Azevedo Nunes, S.L., Alves, M.N.M., Lauton Santos, S., Alenina, N., Bader, M., Ribeiro Resende, R., dos Santos Cruz, J., Souza dos Santos, R.A. and Guatimosim, S.
Hypertension 61
(2): 425-430.
February 2013
Postnatal growth defects in mice with constitutive depletion of central serotonin.
Narboux-Neme, N., Angenard, G., Mosienko, V., Klempin, F., Pitychoutis, P.M., Deneris, E., Bader, M., Giros, B., Alenina, N. and Gaspar, P.
ACS Chemical Neuroscience 4
(1): 171-181.
16 January 2013
(Pro)renin receptor: subcellular localizations and functions.
Sihn, G., Burckle, C., Rousselle, A., Reimer, T. and Bader, M.
Frontiers in Bioscience 5
: 500-508.
1 January 2013
Activation of the PTHRP/adenylate cyclase pathway promotes differentiation of rat XEN cells into parietal endoderm, whereas Wnt/β-catenin signaling promotes differentiation into visceral endoderm.
Chuykin, I., Schulz, H., Guan, K. and Bader, M.
Journal of Cell Science 126
(Pt 1): 128-138.
1 January 2013
Antioxidant/oxidant status and cardiac function in bradykinin B(1)- and B(2)-receptor null mice.
Delemasure, S., Blaes, N., Richard, C., Couture, R., Bader, M., Dutartre, P., Girolami, J.P., Connat, J.L. and Rochette, L.
Physiological Research 62
(5): 511-517.
2013
Laser fusion of mouse embryonic cells and intra-embryonic fusion of blastomeres without affecting the embryo integrity.
Krivokharchenko, A., Karmenyan, A., Sarkisov, O., Bader, M., Chiou, A. and Shakhbazyan, A.
PLoS ONE 7
(12): e50029.
5 December 2012
Exercise induces renin-angiotensin system unbalance and high collagen expression in the heart of Mas-deficient mice.
Guimaraes, G.G., Santos, S.H.S., Oliveira, M.L., Pimenta-Veloso, E.P., Motta, D.F., Martins, A.S., Alenina, N., Bader, M., Santos, R.A.S. and Campagnole-Santos, M.J.
Peptides 38
(1): 54-61.
November 2012
Increased circulating angiotensin-(1-7) protects white adipose tissue against development of a proinflammatory state stimulated by high-fat diet.
Santos, S.H.S., Rodrigues Fernandes, L., Santos Pereira, C., Senna Guimaraes, A.L., de Paula, A.M.B., Campagnole-Santos, M.J., Alvarez-Leite, J.I., Bader, M. and Santos, R.A.S.
Regulatory Peptides 178
(1-3): 64-70.
10 October 2012
Altered regional blood flow distribution in Mas-deficient mice.
Botelho-Santos, G.A., Bader, M., Alenina, N. and Santos, R.A.
Therapeutic Advances in Cardiovascular Disease 6
(5): 201-211.
October 2012
Bradykinin inhibits hepatic gluconeogenesis in obese mice.
Castilho Barros, C., Haro, A., Russo, F.J., Schadock, I., Soares Almeida, S., Castellani Reis, F., Rocha Moraes, M., Haidar, A., Hirata, A.E., Mori, M.A., Pereira Bacurau, R.F., Wuertele, M., Bader, M., Bosco Pesquero, J. and Araujo, R.C.
Laboratory Investigation 92
(10): 1419-1427.
October 2012
Decreased hepatic gluconeogenesis in transgenic rats with increased circulating angiotensin-(1-7).
Bilman, V., Mares-Guia, L., Nadu, A.P., Bader, M., Campagnole-Santos, M.J., Santos, R.A.S. and Santos, S.H.S.
Peptides 37
(2): 247-251.
October 2012
Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation.
Chan, M.V., Bubb, K.J., Noyce, A., Villar, I.C., Duchene, J., Hobbs, A.J., Scotland, R.S. and Ahluwalia, A.
British Journal of Pharmacology 167
(4): 805-817.
October 2012
Endothelium dependent expression and underlying mechanisms of des-Arg(9)-bradykinin-induced B(1)R-mediated vasoconstriction in rat portal vein.
Basei, F.L., Cabrini, D.A., Figueiredo, C.P., Forner, S., Hara, D.B., Nascimento, A.F.Z., Ceravolo, G.S., Carvalho, M.H.C., Bader, M., Medeiros, R. and Calixto, J.B.
Peptides 37
(2): 216-224.
October 2012
Kinin b(1) receptor in adipocytes regulates glucose tolerance and predisposition to obesity.
Mori, M.A., Sales, V.M., Motta, F.L., Fonseca, R.G., Alenina, N., Guadagnini, D., Schadock, I., Silva, E.D., Torres, H.A., Dos Santos, E.L., Castro, C.H., D'Almeida, V., Andreotti, S., Campana, A.B., Sertie, R.A., Saad, M.J., Lima, F.B., Bader, M. and Pesquero, J.B.
PLoS ONE 7
(9): e44782.
14 September 2012
Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation.
Albert-Weissenberger, C., Stetter, C., Meuth, S.G., Goebel, K., Bader, M., Siren, A.L. and Kleinschnitz, C.
Journal of Cerebral Blood Flow and Metabolism 32
(9): 1747-1756.
September 2012
Blood pressure and renin-angiotensin system resetting in transgenic rats with elevated plasma Val5-angiotensinogen.
Bohlender, J., Bader, M., Menard, J. and Nussberger, J.
Journal of Hypertension 30
(8): 1597-1605.
August 2012
Altered glucose homeostasis and hepatic function in obese mice deficient for both kinin receptor genes.
Barros, C.C., Haro, A., Russo, F.J.V.P., Schadock, I., Almeida, S.S., Ribeiro, R.A., Vanzela, E.C., Lanzoni, V.P., Barros, F.C., Moraes, M.R., Mori, M.A., Bacurau, R.F.P., Wurtele, M., Boschero, A.C., Carneiro, E.M., Bader, M., Pesquero, J.B. and Araujo, R.C.
PLoS ONE 7
(7): e40573.
19 July 2012
Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin.
Mosienko, V., Bert, B., Beis, D., Matthes, S., Fink, H., Bader, M. and Alenina, N.
Translational Psychiatry 2
(5): e122.
29 May 2012
Pioglitazone prevents capillary rarefaction in streptozotocin-diabetic rats independently of glucose control and vascular endothelial growth factor expression.
Ashoff, A., Qadri, F., Eggers, R., Joehren, O., Raasch, W. and Dendorfer, A.
Journal of Vascular Research 49
(3): 260-266.
May 2012
Regulation of karyopherin alpha1 and nuclear import by mammalian target of rapamycin.
Fielhaber, J.A., Tan, J., Joung, K.B., Attias, O., Huegel, S., Bader, M., Roux, P.P. and Kristof, A.S.
Journal of Biological Chemistry 287
(18): 14325-14335.
27 April 2012
Cardiovascular responses evoked by activation or blockade of GABA(A) receptors in the hypothalamic PVN are attenuated in transgenic rats with low brain angiotensinogen.
Gomes da Silva, A.Q., Xavier, C.H., Campagnole-Santos, M.J., Caligiorne, S.M., Baltatu, O.C., Bader, M., Santos, R.A. and Fontes, M.A.
Brain Research 1448
: 101-110.
11 April 2012
Angiotensin-(1-7) receptor Mas is an essential modulator of extracellular matrix protein expression in the heart.
Gava, E., de Castro, C.H., Ferreira, A.J., Colleta, H., Melo, M.B., Alenina, N., Bader, M., Oliveira, L.A., Santos, R.A.S. and Kitten, G.T.
Regulatory Peptides 175
(1-3): 30-42.
10 April 2012
Generation of rat-induced pluripotent stem cells: reprogramming and culture medium.
Liskovykh, M.A., Chuykin, I.A., Ranjan, A., Safina, D.A., Tolkunova, E.N., Minina, Y.M., Zhdanova, N.S., Dyban, P.A., Mullins, J.J., Kostyleva, E.I., Chikhirzhina, E.V., Bader, M., Alenina, N. and Tomilin, A.N.
Cell and Tissue Biology 6
(2): 115-121.
April 2012
Genetic manipulations and examination of differentiation properties of rat induced pluripotent cells.
Liskovykh, M.A., Chuykin, I.A., Ranjan, A., Popova, E., Tolkunova, E.N., Chechik, L.L., Malinin, A.Y., Morozova, A.V., Mosienko, V., Bader, M., Alenina, N. and Tomilin, A.N.
Cell and Tissue Biology 6
(2): 122-127.
April 2012
Impaired nociception and peripheral opioid antinociception in mice lacking both kinin b1 and b2 receptors.
Cayla, C., Labuz, D., Machelska, H., Bader, M., Schaefer, M. and Stein, C.
Anesthesiology 116
(2): 448-457.
February 2012
Axonal transcription factors signal retrogradely in lesioned peripheral nerve.
Ben-Yaakov, K., Dagan, S.Y., Segal-Ruder, Y., Shalem, O., Vuppalanchi, D., Willis, D.E., Yudin, D., Rishal, I., Rother, F., Bader, M., Blesch, A., Pilpel, Y., Twiss, J.L. and Fainzilber, M.
EMBO Journal 31
(6): 1350-1363.
13 January 2012
Identification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-AT1, non-AT2 angiotensin binding site.
Wangler, N.J., Santos, K.L., Schadock, I., Hagen, F.K., Escher, E., Bader, M., Speth, R.C. and Karamyan, V.T.
Journal of Biological Chemistry 287
(1): 114-122.
2 January 2012
Angiotensin-(1-7) Mas-receptor deficiency decreases peroxisome proliferator-activated receptor gamma expression in adipocytes.
Mario, E.G., Santos, S.H.S., Ferreira, A.V.M., Bader, M., Santos, R.A.S. and Botion, L.M.
Peptides 33
(1): 174-177.
January 2012
Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.
Lazaroni, T.L.N., Raslan, A.C.S., Fontes, W.R.P., de Oliveira, M.L., Bader, M., Alenina, N., Moraes, M.F.D., Dos Santos, R.A. and Pereira, G.S.
Neurobiology of Learning and Memory 97
(1): 113-123.
January 2012
Renoprotective effects of AVE0991, a nonpeptide Mas receptor agonist, in experimental acute renal injury.
Barroso, L.C., Silveira, K.D., Lima, C.X., Borges, V., Bader, M., Rachid, M., Souza Santos, R.A., Souza, D.G., Simoes e Silva, A.C. and Teixeira, M.M.
International Journal of Hypertension 2012
: 808726.
2012
Prorenin receptor is essential for podocyte autophagy and survival.
Riediger, F., Quack, I., Qadri, F., Hartleben, B., Park, J.K., Potthoff, S.A., Sohn, D., Sihn, G., Rousselle, A., Fokuhl, V., Maschke, U., Purfürst, B., Schneider, W., Rump, L.C., Luft, F.C., Dechend, R., Bader, M., Huber, T.B., Nguyen, G. and Mueller, D.N.
Journal of the American Society of Nephrology 22
(12): 2193-2202.
December 2011
Derivation, characterization, and stable transfection of induced pluripotent stem cells from Fischer344 rats.
Liskovykh, M., Chuykin, I., Ranjan, A., Safina, D., Popova, E., Tolkunova, E., Mosienko, V., Minina, J.M., Zhdanova, N.S., Mullins, J.J., Bader, M., Alenina, N. and Tomilin, A.
PLoS ONE 6
(11): e27345.
4 November 2011
Stress worsens endothelial function and ischemic stroke via glucocorticoids.
Balkaya, M., Prinz, V., Custodis, F., Gertz, K., Kronenberg, G., Kroeber, J., Fink, K., Plehm, R., Gass, P., Laufs, U. and Endres, M.
Stroke 42
(11): 3258-3264.
November 2011
B(1) and B(2) kinin receptor participation in hyperproliferative and inflammatory skin processes in mice.
Pietrovski, E.F., Paludo, K.S., Mendes, D.A., Guimaraes, F.D., Veiga, S.S., Buchi, D.D., Fonseca, R.G., Zampronio, A.R., Bader, M., Pesquero, J.B., Ferreira, J., Otuki, M.F. and Cabrini, D.A.
Journal of Dermatological Science 64
(1): 23-30.
October 2011
Mas receptors in modulating relaxation induced by perivascular adipose tissue.
Lee, R.M.K.W., Bader, M., Alenina, N., Santos, R.A.S., Gao, Y.J. and Lu, C.
Life Sciences 89
(13-14): 467-472.
26 September 2011
Angioprotectin: an angiotensin II-like peptide causing vasodilatory effects.
Jankowski, V., Toelle, M., Santos, R.A., Guenthner, T., Krause, E., Beyermann, M., Welker, P., Bader, M., Pinheiro, S.V.B., Sampaio, W.O., Lautner, R., Kretschmer, A., van der Giet, M., Zidek, W. and Jankowski, J.
FASEB Journal 25
(9): 2987-2995.
September 2011
Arteriogenesis is modulated on bradykinin receptor signaling.
Hillmeister, P., Gatzke, N., Duelsner, A., Bader, M., Schadock, I., Hoefer, I., Hamann, I., Infante-Duarte, C., Jung, G., Troidl, K., Urban, D., Stawowy, P., Frentsch, M., Li, M., Nagorka, S., Wang, H., Shi, Y., le Noble, F. and Buschmann, I.
Circulation Research 109
(5): 524-533.
19 August 2011
Lrp5 functions in bone to regulate bone mass.
Cui, Y., Niziolek, P.J., Macdonald, B.T., Zylstra, C.R., Alenina, N., Robinson, D.R., Zhong, Z., Matthes, S., Jacobsen, C.M., Conlon, R.A., Brommage, R., Liu, Q., Mseeh, F., Powell, D.R., Yang, Q.M., Zambrowicz, B., Gerrits, H., Gossen, J.A., He, X., Bader, M., Williams, B.O., Warman, M.L. and Robling, A.G.
Nature Medicine 17
(6): 684-691.
June 2011
Platelet-derived serotonin links vascular disease and tissue fibrosis.
Dees, C., Akhmetshina, A., Zerr, P., Reich, N., Palumbo, K., Horn, A., Juengel, A., Beyer, C., Kroenke, G., Zwerina, J., Reiter, R., Alenina, N., Maroteaux, L., Gay, S., Schett, G., Distler, O. and Distler, J.H.
Journal of Experimental Medicine 208
(5): 961-972.
9 May 2011
Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling.
Guimaraes, P.B., Alvarenga, E.C., Siqueira, P.D., Paredes-Gamero, E.J., Sabatini, R.A., Morais, R.L., Reis, R.I., Santos, E.L., Teixeira, L.G., Casarini, D.E., Martin, R.P., Shimuta, S.I., Carmona, A.K., Nakaie, C.R., Jasiulionis, M.G., Ferreira, A.T., Pesquero, J.L., Oliveira, S.M., Bader, M., Costa-Neto, C.M. and Pesquero, J.B.
Hypertension 57
(5): 965-972.
May 2011
Effect of culture conditions on viability of mouse and rat embryos developed in vitro.
Popova, E., Bader, M. and Krivokharchenko, A.
Genes 2
(2): 332-344.
1 April 2011
Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension.
Rothman, R.B., Cadet, J.L., Dersch, C.M., McCoy, M.T., Lehrmann, E., Becker, K.G., Bader, M., Alenina, N. and Baumann, M.H.
PLoS ONE 6
(3): e17735.
25 March 2011
Effects of electric field on early preimplantation development in vitro in mice and rats.
Popova, E., Bader, M. and Krivokharchenko, A.
Human Reproduction 26
(3): 662-670.
March 2011
Importin alpha7 is essential for zygotic genome activation and early mouse development.
Rother, F., Shmidt, T., Popova, E., Krivokharchenko, A., Huegel, S., Vilianovich, L., Ridders, M., Tenner, K., Alenina, N., Koehler, M., Hartmann, E. and Bader, M.
PLoS ONE 6
(3): e18310.
March 2011
Controlling cardiomyocyte length: The role of renin and PPAR-γ.
Hinrichs, S., Heger, J., Schreckenberg, R., Wenzel, S., Euler, G., Arens, C., Bader, M., Rosenkranz, S., Caglayan, E. and Schlueter, K.D.
Cardiovascular Research 89
(2): 344-352.
1 February 2011
Forced expression of Lmx1b enhances differentiation of mouse ES cells into serotonergic neurons.
Dolmazon, V., Alenina, N., Markossian, S., Mancip, J., Van de Vrede, Y., Fontaine, E., Dehay, C., Kennedy, H., Bader, M., Savatier, P. and Bernat, A.
Stem Cells and Development 20
(2): 301-311.
February 2011
Functional expression of angiotensinogen depends on splicing enhancers in exon 2.
Cardoso, C.C., Cabrini, D.A., May, M., Bhagat, C.S., Eleno, N., Cayla, C., Walther, T. and Bader, M.
Molecular and Cellular Endocrinology 332
(1-2): 228-233.
30 January 2011
ACE activity is modulated by the enzyme alpha-galactosidase A.
Batista, E.C., Carvalho, L.R., Casarini, D.E., Carmona, A.K., Dos Santos, E.L., da Silva, E.D., Dos Santos, R.A., Nakaie, C.R., Rojas, M.V., de Oliveira, S.M., Bader, M., D'Almeida, V., Martins, A.M., de Picoly Souza, K. and Pesquero, J.B.
Journal of Molecular Medicine 89
(1): 65-74.
January 2011
Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus.
Gabriel, G., Klingel, K., Otte, A., Thiele, S., Hudjetz, B., Arman-Kalcek, G., Sauter, M., Shmidt, T., Rother, F., Baumgarte, S., Keiner, B., Hartmann, E., Bader, M., Brownlee, G.G., Fodor, E. and Klenk, H.D.
Nature Communications 2
(1): 156.
January 2011
An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect.
Fraga-Silva, R.A., Costa-Fraga, F.P., Sousa, F.B., Alenina, N., Bader, M., Sinisterra, R.D. and Santos, R.A.
Clinics 66
(5): 837-841.
2011
Generation of rat induced pluripotent stem cells: the analysis of reprogramming and culturing media.
Liskovykh, M.A., Chuykin, I.A., Ranjan, A., Safina, D.A., Tolkunova, E.N., Minina, Y.M., Zhdanova, N.S., Dyban, P.A,, Mullins, J., Kostyleva, E.I., Chikhirzhina, E.V., Bader, M., Alenina, N. and Tomilin, A.N.
Tsitologiia 53
(12): 939-945.
2011
Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron.
Pohl, M., Kaminski, H., Castrop, H., Bader, M., Himmerkus, N., Bleich, M., Bachmann, S. and Theilig, F.
Journal of Biological Chemistry 285
(53): 41935-41946.
31 December 2010
Knockout of angiotensin 1-7 receptor Mas worsens the course of two-kidney, one-clip Goldblatt hypertension: roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II.
Rakusan, D., Buergelova, M., Vaneckova, I., Vanourkova, Z., Huskova, Z., Skaroupkova, P., Mrazova, I., Opocensky, M., Kramer, H.J., Netuka, I., Maly, J., Alenina, N., Bader, M., Santos, R.A.S. and Cervenka, L.
Kidney and Blood Pressure Research 33
(6): 476-488.
December 2010
Anti-inflammatory effects of the activation of the angiotensin-(1-7) receptor, Mas, in experimental models of arthritis.
Silveira, K.D., Coelho, F.M., Vieira, A.T., Sachs, D., Barroso, L.C., Costa, V.V., Bretas, T.L.B., Bader, M., Sousa, L.P., Silva, T.A., Santos, R.A.S., Simoes E Silva, A.C. and Teixeira, M.M.
Journal of Immunology 185
(9): 5569-5576.
1 November 2010
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.
Werth, M., Walentin, K., Aue, A., Schoenheit, J., Wuebken, A., Pode-Shakked, N., Vilianovitch, L., Erdmann, B., Dekel, B., Bader, M., Barasch, J., Rosenbauer, F., Luft, F.C. and Schmidt-Ott, K.M.
Development 137
(22): 3835-3845.
November 2010
Altered cardiovascular reflexes responses in conscious angiotensin-(1-7) receptor Mas knockout mice.
Moura, M.M., Souza dos Santos, R.A., Campagnole-Santos, M.J., Todiras, M., Bader, M., Alenina, N. and Haibara, A.S.
Peptides 31
(10): 1934-1939.
October 2010
Anxiety-related behaviour of low brain angiotensinogen transgenic rats in the canopy test.
Voigt, J.P., Bader, M., Bert, B., Fink, H. and Rex, A.
Pharmacology Biochemistry and Behavior 96
(4): 429-437.
October 2010
Cardiac magnetic field mapping quantified by Kullback-Leibler entropy detects patients with coronary artery disease.
Gapelyuk, A., Schirdewan, A., Fischer, R. and Wessel, N.
Physiological Measurement 31
(10): 1345-1354.
October 2010
Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation.
Raslan, F., Schwarz, T., Meuth, S.G., Austinat, M., Bader, M., Renne, T., Roosen, K., Stoll, G., Siren, A.L. and Kleinschnitz, C.
Journal of Cerebral Blood Flow and Metabolism 30
(8): 1477-1486.
August 2010
Genexpression und Morphologie der Follikel nach konventionellem Einfrieren und Vitrifikation von humanem Ovarialgewebe [Gene-expression and morphology of follicles after conventional freezing and vitrification of human ovarian tissue].
Isachenko, V., Isachenko, E., Nawroth, F., Wiegratz, I., Kaufmann, M., Lapidus, I., Hancke, K. and Kreienberg, R.
Geburtshilfe und Frauenheilkunde 70
(7): 561-567.
July 2010
Vascular relaxation, antihypertensive effect, and cardioprotection of a novel peptide agonist of the Mas receptor.
Savergnini, S.Q., Beiman, M., Lautner, R.Q., de Paula-Carvalho, V., Allahdadi, K., Pessoa, D.C., Costa-Fraga, F.P., Fraga-Silva, R.A., Cojocaru, G., Cohen, Y., Bader, M., de Almeida, A.P., Rotman, G. and Santos, R.A.
Hypertension 56
(1): 112-120.
July 2010
SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2.
Reiche, J., Theilig, F., Rafiqi, F.H., Carlo, A.S., Militz, D., Mutig, K., Todiras, M., Christensen, E.I., Ellison, D.H., Bader, M., Nykjaer, A., Bachmann, S., Alessi, D. and Willnow, T.E.
Molecular and Cellular Biology 30
(12): 3027-3037.
June 2010
Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7).
Santos, S.H., Felix Braga, J., Mario, E.G., Porto, L.C., Rodrigues-Machado, M.D., Murari, A., Botion, L.M., Alenina, N., Bader, M. and Santos, R.A.
Arteriosclerosis Thrombosis and Vascular Biology 30
(5): 953-61.
May 2010
Visinin-like protein 1 regulates natriuretic peptide receptor B in the heart.
Buttgereit, J., Qadri, F., Monti, J., Langenickel, T.H., Dietz, R., Braunewell, K.H. and Bader, M.
Regulatory Peptides 161
(1-3): 51-57.
9 April 2010
Attenuation of isoproterenol-induced cardiac fibrosis in transgenic rats harboring an angiotensin-(1-7)-producing fusion protein in the heart.
Ferreira, A.J., Castro, C.H., Guatimosim, S., Almeida, P.W.M., Gomes, E.R.M., Dias-Peixoto, M.F., Alves, M.N.A., Fagundes-Moura, C.R., Rentzsch, B., Gava, E., Almeida, A.P., Guimaraes, A.M., Kitten, G.T., Reudelhuber, T., Bader, M. and Santos, R.A.S.
Therapeutic Advances in Cardiovascular Disease 4
(2): 83-96.
April 2010
Autonomic dysregulation in ob/ob mice is improved by inhibition of angiotensin-converting enzyme.
Hilzendeger, A.M., da Costa Goncalves, A.C., Plehm, R., Diedrich, A., Gross, V., Pesquero, J.B. and Bader, M.
Journal of Molecular Medicine 88
(4): 383-390.
April 2010
Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor κB.
Rompe, F., Artuc, M., Hallberg, A., Alterman, M., Stroeder, K., Thoene-Reineke, C., Reichenbach, A., Schacherl, J., Dahloef, B., Bader, M., Alenina, N., Schwaninger, M., Zuberbier, T., Funke-Kaiser, H., Schmidt, C., Schunck, W.H., Unger, T. and Steckelings, U.M.
Hypertension 55
(4): 924-931.
April 2010
Increased blood pressure and water intake in transgenic mice expressing rat tonin in the brain.
Cardoso, C.C., Alenina, N., Ferreira, A.J., Qadri, F., Lima, M.P., Gross, V., Todiras, M., Pesquero, J.B., Pesquero, J.L. and Bader, M.
Biological Chemistry 391
(4): 435-441.
April 2010
Characterization of trophoblast and extraembryonic endoderm cell lineages derived from rat preimplantation embryos.
Chuykin, I., Lapidus, I., Popova, E., Vilianovich, L., Mosienko, V., Alenina, N., Binas, B., Chai, G., Bader, M. and Krivokharchenko, A.
PLoS ONE 5
(3): e9794.
29 March 2010
The past, present and future of angiotensin II type 2 receptor stimulation.
Steckelings, U.M., Rompe, F., Kaschina, E., Namsolleck, P., Grzesiak, A., Funke-Kaiser, H., Bader, M. and Unger, T.
Journal of the Renin Angiotensin Aldosterone System 11
(1): 67-73.
March 2010
alpha(1A)-adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats.
Wenzel, K., Wallukat, G., Qadri, F., Huebner, N., Schulz, H., Hummel, O., Herse, F., Heuser, A., Fischer, R., Heidecke, H., Luft, F.C., Mueller, D.N., Dietz, R. and Dechend, R.
PLoS ONE 5
(2): e9409.
24 February 2010
Signal transduction in CHO-cells stably transfected with domain-selective forms of murine ACE.
Sun, X., Rentzsch, B., Gong, M., Eichhorst, J., Pankow, K., Papsdorf, G., Maul, B., Bader, M. and Siems, W.E.
Biological Chemistry 391
(2-3): 235-244.
February 2010
Alternative splicing and extensive RNA editing of human TPH2 transcripts.
Grohmann, M., Hammer, P., Walther, M., Paulmann, N., Buettner, A., Eisenmenger, W., Baghai, T.C., Schuele, C., Rupprecht, R., Bader, M., Bondy, B., Zill, P., Priller, J. and Walther, D.J.
PLoS ONE 5
(1): e8956.
29 January 2010
Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3',5'-cyclic monophosphate-dependent pathway.
Gomes, E.R., Lara, A.A., Almeida, P.W., Guimaraes, D., Resende, R.R., Campagnole-Santos, M.J., Bader, M., Santos, R.A. and Guatimosim, S.
Hypertension 55
(1): 153-160.
January 2010
Stress sensitivity is increased in transgenic rats with low brain angiotensinogen.
Mueller, H., Kroeger, J., Joehren, O., Szymczak, S., Bader, M., Dominiak, P. and Raasch, W.
Journal of Endocrinology 204
(1): 85-92.
January 2010
The role of bradykinin B(1) and B(2) receptors for secondary brain damage after traumatic brain injury in mice.
Trabold, R., Eroes, C., Zweckberger, K., Relton, J., Beck, H., Nussberger, J., Mueller-Esterl, W., Bader, M., Whalley, E. and Plesnila, N.
Journal of Cerebral Blood Flow and Metabolism 30
(1): 130-139.
January 2010
Rat models of cardiovascular diseases.
Bader, M.
Methods in Molecular Biology 597
: 403-414.
2010
The possibilities of optical laser technologies in cell engineering.
Shakhbazyan, A.K., Karmenyan, A.K., Sviridova-Chailakhyan, T.A., Krivokharchenko, A.S., Chiou, A. and Chailakhyan, L.M.
Doklady Biological Sciences 429
(1): 587-590.
December 2009
Central control of fever and female body temperature by RANKL/RANK.
Hanada, R., Leibbrandt, A., Hanada, T., Kitaoka, S., Furuyashiki, T., Fujihara, H., Trichereau, J., Paolino, M., Qadri, F., Plehm, R., Klaere, S., Komnenovic, V., Mimata, H., Yoshimatsu, H., Takahashi, N., von Haeseler, A., Bader, M., Kilic, S.S., Ueta, Y., Pifl, C., Narumiya, S. and Penninger, J.M.
Nature 462
(7272): 505-509.
26 November 2009
Developmental renin expression in mice with defective renin angiotensin system.
Machura, K., Steppan, D., Neubauer, B., Alenina, N., Coffman, T.M., Facemire, C.M., Hilgers, K.F., Eckardt, K.U., Wagner, C. and Kurtz, A.
American Journal of Physiology Renal Physiology 297
(5): F1371-F1380.
November 2009
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation.
Paulmann, N., Grohmann, M., Voigt, J.P., Bert, B., Vowinckel, J., Bader, M., Skelin, M., Jevsek, M., Fink, H., Rupnik, M. and Walther, D.J.
PLoS Biology 7
(10): e1000229.
27 October 2009
Impairment of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension.
Buergelova, M., Vanourkova, Z., Thumova, M., Dvorak, P., Opocensky, M., Kramer, H.J., Zelizko, M., Maly, J., Bader, M. and Cervenka, L.
Journal of Hypertension 27
(10): 1988-2000.
October 2009
Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E.
Merino, V.F., Todiras, M., Mori, M.A., Sales, V.M., Fonseca, R.G., Saul, V., Tenner, K., Bader, M. and Pesquero, J.B.
Journal of Molecular Medicine 87
(10): 953-963.
October 2009
The use of laser for obtaining recipient cytoplasts for mammalian nuclear transfer.
Shakhbazyan, A.K., Sviridova-Chailakhyan, T.A., Karmenyan, A.K., Krivokharchenko, A.S., Chiou, A. and Chailakhyan, L.M.
Doklady Biological Sciences 428
: 475-478.
October 2009
Use of picosecond infrared laser for micromanipulation of early mammalian embryos.
Karmenyan, A.V., Shakhbazyan, A.K., Sviridova-Chailakhyan, T.A., Krivokharchenko, A.S., Chiou, A.E. and Chailakhyan, L.M.
Molecular Reproduction and Development 76
(10): 975-983.
October 2009
Isolation of Oct4-expressing extraembryonic endoderm precursor cell lines.
Debeb, B.G., Galat, V., Epple-Farmer, J., Iannaccone, S., Woodward, W.A., Bader, M., Iannaccone, P. and Binas, B.
PLoS ONE 4
(9): e7216.
28 September 2009
The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.
Schulz, H., Kolde, R., Adler, P., Aksoy, I., Anastassiadis, K., Bader, M., Billon, N., Boeuf, H., Bourillot, P.Y., Buchholz, F., Dani, C., Doss, M.X., Forrester, L., Gitton, M., Henrique, D., Hescheler, J., Himmelbauer, H., Huebner, N., Karantzali, E., Kretsovali, A., Lubitz, S., Pradier, L., Rai, M., Reimand, J., Rolletschek, A., Sachinidis, A., Savatier, P., Stewart, F., Storm, M.P., Trouillas, M., Vilo, J., Welham, M.J., Winkler, J., Wobus, A.M. and Hatzopoulos, A.K.
PLoS ONE 4
(9): e6804.
3 September 2009
Cross talk between kinin and angiotensin II receptors in mouse abdominal aorta.
Rodrigues, E.S., Martin, R.P., Felipe, S.A., Bader, M., Oliveira, S.M. and Shimuta, S.I.
Biological Chemistry 390
(9): 907-913.
September 2009
Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease.
Gramlich, M., Michely, B., Krohne, C., Heuser, A., Erdmann, B., Klaassen, S., Hudson, B., Magarin, M., Kirchner, F., Todiras, M., Granzier, H., Labeit, S., Thierfelder, L. and Gerull, B.
Journal of Molecular and Cellular Cardiology 47
(3): 352-358.
September 2009
Connective tissue growth factor overexpression in cardiomyocytes promotes cardiac hypertrophy and protection against pressure overload.
Panek, A.N., Posch, M.G., Alenina, N., Ghadge, S.K., Erdmann, B., Popova, E., Perrot, A., Geier, C., Dietz, R., Morano, I., Bader, M. and Oezcelik, C.
PLoS ONE 4
(8): e6743.
25 August 2009
Cardiomyopathy mutations reveal variable region of myosin converter as major element of cross-bridge compliance.
Seebohm, B., Matinmehr, F., Koehler, J., Francino, A., Navarro-Lopez, F., Perrot, A., Oezcelik, C., McKenna, W.J., Brenner, B. and Kraft, T.
Biophysical Journal 97
(3): 806-824.
5 August 2009
A role of the (pro)renin receptor in neuronal cell differentiation.
Contrepas, A., Walker, J., Koulakoff, A., Franek, K.J., Qadri, F., Giaume, C., Corvol, P., Schwartz, C.E. and Nguyen, G.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 297
(2): R250-R257.
August 2009
Growth arrest specific protein 6 participates in DOCA-induced target-organ damage.
Park, J.K., Theuer, S., Kirsch, T., Lindschau, C., Klinge, U., Heuser, A., Plehm, R., Todiras, M., Carmeliet, P., Haller, H., Luft, F.C., Mueller, D.N. and Fiebeler, A.
Hypertension 54
(2): 359-364.
August 2009
Human ovarian tissue vitrification versus conventional freezing: morphological, endocrinological, and molecular biological evaluation.
Isachenko, V., Lapidus, I., Isachenko, E., Krivokharchenko, A., Kreienberg, R., Woriedh, M., Bader, M. and Weiss, J.
Reproduction 138
(2): 319-327.
August 2009
Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system.
Schulze-Topphoff, U., Prat, A., Prozorovski, T., Siffrin, V., Paterka, M., Herz, J., Bendix, I., Ifergan, I., Schadock, I., Mori, M.A., Van Horssen, J., Schroeter, F., Smorodchenko, A., Han, M.H., Bader, M., Steinman, L., Aktas, O. and Zipp, F.
Nature Medicine 15
(7): 788-793.
July 2009
Serotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17).
Duerschmied, D., Canault, M., Lievens, D., Brill, A., Cifuni, S.M., Bader, M. and Wagner, D.D.
Journal of Thrombosis and Haemostasis 7
(7): 1163-1171.
July 2009
Growth retardation and altered autonomic control in mice lacking brain serotonin.
Alenina, N., Kikic, D., Todiras, M., Mosienko, V., Qadri, F., Plehm, R., Boye, P., Vilianovitch, L., Sohr, R., Tenner, K., Hoertnagl, H. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 106
(25): 10332-10337.
23 June 2009
Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin.
Kahn, R., Hellmark, T., Leeb-Lundberg, L.M., Akbari, N., Todiras, M., Olofsson, T., Wieslander, J., Christensson, A., Westman, K., Bader, M., Mueller-Esterl, W. and Karpman, D.
Journal of Immunology 182
(12): 7906-7915.
15 June 2009
Regulatory T cells ameliorate angiotensin II-induced cardiac damage.
Kvakan, H., Kleinewietfeld, M., Qadri, F., Park, J.K., Fischer, R., Schwarz, I., Rahn, H.P., Plehm, R., Wellner, M., Elitok, S., Gratze, P., Dechend, R., Luft, F.C. and Mueller, D.N.
Circulation 119
(22): 2904-2912.
9 June 2009
Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria.
Pinheiro, S.V., Ferreira, A.J., Kitten, G.T., da Silveira, K.D., da Silva, D.A., Santos, S.H., Gava, E., Castro, C.H., Magalhaes, J.A., da Mota, R.K., Botelho-Santos, G.A., Bader, M., Alenina, N., Santos, R.A. and Simoes E Silva, A.C.
Kidney International 75
(11): 1184-1193.
1 June 2009
CENTB5 gene expression in human and mouse.
Shubina, D.M., Suchkova, I.O., Slominskaya, N.A., Alenina, N., Bader, M. and Patkin, E.L.
Molecular Biology 43
(3): 374-380.
June 2009
Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy.
Westermann, D., Walther, T., Savvatis, K., Sobirey, M., Riad, A., Bader, M., Schultheiss, H.P. and Tschoepe, C.
Diabetes 58
(6): 1373-1381.
June 2009
The role of angiotensin-(1-7) receptor Mas in spermatogenesis in mice and rats.
Leal, M.C., Pinheiro, S.V., Ferreira, A.J., Santos, R.A., Bordoni, L.S., Alenina, N., Bader, M. and Franca, L.R.
Journal of Anatomy 214
(5): 736-743.
May 2009
Inducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown.
Kotnik, K., Popova, E., Todiras, M., Mori, M.A., Alenina, N., Seibler, J. and Bader, M.
PLoS ONE 4
(4): e5124.
2 April 2009
Low immunogenicity of endothelial derivatives from rat embryonic stem cell-like cells.
Ladhoff, J., Bader, M., Broesel, S., Effenberger, E., Westermann, D., Volk, H.D. and Seifert, M.
Cell Research 19
(4): 507-518.
April 2009
Energy metabolism in human renin-gene transgenic rats. Does renin contribute to obesity?
Gratze, P., Boschmann, M., Dechend, R., Qadri, F., Malchow, J., Graeske, S., Engeli, S., Janke, J., Springer, J., Contrepas, A., Plehm, R., Klaus, S., Nguyen, G., Luft, F.C. and Mueller, D.N.
Hypertension 53
(3): 516-523.
March 2009
The kinin B1 receptor contributes to the cardioprotective effect of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in mice.
Xu, J., Carretero, O.A., Shesely, E.G., Rhaleb, N.E., Yang, J.J., Bader, M. and Yang, X.P.
Experimental Physiology 94
(3): 322-329.
March 2009
Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol.
Wendt, N., Schulz, A., Qadri, F., Bolbrinker, J., Kossmehl, P., Winkler, K., Stoll, M., Vetter, R. and Kreutz, R.
Cardiovascular Research 81
(3): 618-626.
15 February 2009
Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunction.
da Costa Goncalves, A.C., Tank, J., Diedrich, A., Hilzendeger, A., Plehm, R., Bader, M., Luft, F.C., Jordan, J. and Gross, V.
Hypertension 53
(2): 387-392.
February 2009
Efficient production of nuclear transferred rat embryos by modified methods of reconstruction.
Popova, E., Bader, M. and Krivokharchenko, A.
Molecular Reproduction and Development 76
(2): 208-216.
February 2009
The bradykinin B2 receptor in the early immune response against Listeria infection.
Kaman, W.E., Wolterink, A.F., Bader, M., Boele, L.C. and van der Kleij, D.
Medical Microbiology and Immunology 198
(1): 39-46.
February 2009
Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying Acromesomelic Dysplasia type Maroteaux.
Hume, A.N., Buttgereit, J., Al-Awadhi, A.M., Al-Suwaidi, S.S., John, A., Bader, M., Seabra, M.C., Al-Gazali, L. and Ali, B.R.
Human Molecular Genetics 18
(2): 267-277.
15 January 2009
The non-peptide kinin receptor antagonists FR 173657 and SSR 240612: Preclinical evidence for the treatment of skin inflammation.
Pietrovski, E.F., Otuki, M.F., Regoli, D., Bader, M., Pesquero, J.B., Cabrini, D.A. and Zampronio, A.R.
Regulatory Peptides 152
(1-3): 67-72.
8 January 2009
Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema.
Austinat, M., Braeuninger, S., Pesquero, J.B., Brede, M., Bader, M., Stoll, G., Renne, T. and Kleinschnitz, C.
Stroke 40
(1): 285-293.
January 2009
Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy.
Klein, J., Gonzalez, J., Duchene, J., Esposito, L., Pradere, J.P., Neau, E., Delage, C., Calise, D., Ahluwalia, A., Carayon, P., Pesquero, J.B., Bader, M., Schanstra, J.P. and Bascands, J.L.
FASEB Journal 23
(1): 134-142.
January 2009
Excessive hypertension and end-organ damage in a transgenic mouse line carrying the rat angiotensinogen gene.
Xu, P., Wang, Y., Sterner-Kock, A., Bader, M., Schultheiss, H.P. and Walther, T.
Journal of Cardiovascular Pharmacology 53
(1): 38-43.
January 2009
Highlights of the 13th Annual Meeting of the European Council for Cardiovascular Research. 13th Annual Meeting of the European Council for Cardiovascular Research (ECCR). Nice, France, 10-12 October, 2008.
Bader, M.
Future Cardiology 5
(1): 23-25.
January 2009
Exposure to ultrafine carbon particles at levels below detectable pulmonary inflammation affects cardiovascular performance in spontaneously hypertensive rats.
Upadhyay, S., Stoeger, T., Harder, V., Thomas, R.F., Schladweiler, M.C., Semmler-Behnke, M., Takenaka, S., Karg, E., Reitmeir, P., Bader, M., Stampfl, A., Kodavanti, U.P. and Schulz, H.
Particle and Fibre Toxicology 5
(1): 19.
4 December 2008
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart.
Mercure, C., Yogi, A., Callera, G.E., Aranha, A.B., Bader, M., Ferreira, A.J., Santos, R.A., Walther, T., Touyz, R.M. and Reudelhuber, T.L.
Circulation Research 103
(11): 1319-1326.
21 November 2008
Kinin B2 receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice.
Dos Santos, A.C., Roffe, E., Arantes, R.M., Juliano, L., Pesquero, J.L., Pesquero, J.B., Bader, M., Teixeira, M.M. and Carvalho-Tavares, J.
Journal of Neuroinflammation 5
(1): 49.
5 November 2008
Ablation of angiotensin (1-7) receptor Mas in C57Bl/6 mice causes endothelial dysfunction.
Rabelo, L.A., Xu, P., Todiras, M., Sampaio, W.O., Buttgereit, J., Bader, M., Santos, R.A. and Alenina, N.
Journal of the American Society of Hypertension 2
(6): 418-424.
November 2008
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.
Rentzsch, B., Todiras, M., Iliescu, R., Popova, E., Campos, L.A., Oliveira, M.L., Baltatu, O.C., Santos, R.A. and Bader, M.
Hypertension 52
(5): 967-973.
November 2008
Generation and characterization of a GFP transgenic rat line for embryological research.
Popova, E., Rentzsch, B., Bader, M. and Krivokharchenko, A.
Transgenic Research 17
(5): 955-963.
October 2008
Role of the multidomain protein spinophilin in blood pressure and cardiac function regulation.
da Costa-Goncalves, A.C., Tank, J., Plehm, R., Diedrich, A., Todiras, M., Gollasch, M., Heuser, A., Wellner, M., Bader, M., Jordan, J., Luft, F.C. and Gross, V.
Hypertension 52
(4): 702-707.
October 2008
Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice.
Xi, L., Das, A., Zhao, Z.Q., Merino, V.F., Bader, M. and Kukreja, R.C.
Circulation 118
(14 Suppl): S32-S37.
30 September 2008
Molecular mechanisms involved in the angiotensin-(1-7)/Mas signaling pathway in cardiomyocytes.
Dias-Peixoto, M.F., Santos, R.A., Gomes, E.R., Alves, M.N., Almeida, P.W., Greco, L., Rosa, M., Fauler, B., Bader, M., Alenina, N. and Guatimosim, S.
Hypertension 52
(3): 542-548.
September 2008
Production of reconstructed two-cell rat embryos after chemical inactivation of chromosomes in MII oocytes by etoposide.
Zaitseva, Y.A., Bader, M. and Krivokharchenko, A.S.
Russian Journal of Developmental Biology 39
(5): 275-278.
September 2008
Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1-7)3292 rats.
Nadu, A.P., Ferreira, A.J., Reudelhuber, T.L., Bader, M. and Santos, R.A.
Journal of the American Society of Hypertension 2
(5): 341-348.
September 2008
Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts.
Nocito, A., Dahm, F., Jochum, W., Jang, J.H., Georgiev, P., Bader, M., Graf, R. and Clavien, P.A.
Cancer Research 68
(13): 5152-5158.
1 July 2008
Aggravation of viral hepatitis by platelet-derived serotonin.
Lang, P.A., Contaldo, C., Georgiev, P., El-Badry, A.M., Recher, M., Kurrer, M., Cervantes-Barragan, L., Ludewig, B., Calzascia, T., Bolinger, B., Merkler, D., Odermatt, B., Bader, M., Graf, R., Clavien, P.A., Hegazy, A.N., Loehning, M., Harris, N.L., Ohashi, P.S., Hengartner, H., Zinkernagel, R.M. and Lang, K.S.
Nature Medicine 14
(7): 756-761.
July 2008
Increased susceptibility to endotoxic shock in transgenic rats with endothelial overexpression of kinin B(1) receptors.
Merino, V.F., Todiras, M., Campos, L.A., Saul, V., Popova, E., Baltatu, O.C., Pesquero, J.B. and Bader, M.
Journal of Molecular Medicine 86
(7): 791-798.
July 2008
Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice.
Dempsie, Y., Morecroft, I., Welsh, D.J., Macritchie, N.A., Herold, N., Loughlin, L., Nilsen, M., Peacock, A.J., Harmar, A., Bader, M. and Maclean, M.R.
Circulation 2008
(117): 2928-2937.
3 June 2008
Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells.
Batenburg, W.W., de Bruin, R.J., van Gool, J.M., Mueller, D.N., Bader, M., Nguyen, G. and Danser, A.H.
Arteriosclerosis Thrombosis and Vascular Biology 28
(6): 1151-1157.
June 2008
Doxorubicin cardiomyopathy-induced inflammation and apoptosis are attenuated by gene deletion of the kinin B1 receptor.
Westermann, D., Lettau, O., Sobirey, M., Riad, A., Bader, M., Schultheiss, H.P. and Tschoepe, C.
Biological Chemistry 389
(6): 713-718.
June 2008
Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity.
Mori, M.A., Araújo, R.C., Reis, F.C., Sgai, D.G., Fonseca, R.G., Barros, C.C., Merino, V.F., Passadore, M., Barbosa, A.M., Ferrari, B., Carayon, P., Castro, C.H., Shimuta, S.I., Luz, J., Bascands, J.L., Schanstra, J.P., Even, P.C., Oliveira, S.M., Bader, M. and Pesquero, J.B.
Diabetes 57
(6): 1491-1500.
June 2008
Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
Gratze, P., Dechend, R., Stocker, C., Park, J.K., Feldt, S., Shagdarsuren, E., Wellner, M., Gueler, F., Rong, S., Gross, V., Obst, M., Plehm, R., Alenina, N., Zenclussen, A., Titze, J., Small, K., Yokota, Y., Zenke, M., Luft, F.C. and Mueller, D.N.
Circulation 117
(20): 2645-2656.
20 May 2008
Post-infarct cardiac sympathetic hyperactivity regulates galanin expression.
Ewert, T.J., Gritman, K.R., Bader, M. and Habecker, B.A.
Neuroscience Letters 436
(2): 163-166.
9 May 2008
Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder.
Andre, E., Gazzieri, D., Bardella, E., Ferreira, J., Mori, M.A., Saul, V.V., Bader, M., Calixto, J.B., De Giorgio, R., Corinaldesi, R., Geppetti, P. and Trevisani, M.
Gut 57
(5): 628-633.
May 2008
Baroreflex control of heart rate and renal sympathetic nerve activity in rats with low brain angiotensinogen.
Caligiorne, S.M., Silva, A.Q., Fontes, M.A., Silva, J.R., Baltatu, O.C., Bader, M., Santos, R.A. and Campagnole-Santos, M.J.
Neuropeptides 42
(2): 159-168.
April 2008
Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy.
Murtaza, I., Wang, H.X., Feng, X., Alenina, N., Bader, M., Prabhakar, B.S. and Li, P.F.
Journal of Biological Chemistry 283
(10): 5996-6004.
7 March 2008
ACE activity is modulated by kinin B2 receptor.
Sabatini, R.A., Guimaraes, P.B., Fernandes, L., Reis, F.C., Bersanetti, P.A., Mori, M.A., Navarro, A., Hilzendeger, A.M., Santos, E.L., Andrade, M.C., Chagas, J.R., Pesquero, J.L., Casarini, D.E., Bader, M., Carmona, A.K. and Pesquero, J.B.
Hypertension 51
(3): 689-695.
March 2008
Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway.
Depping, R., Steinhoff, A., Schindler, S.G., Friedrich, B., Fagerlund, R., Metzen, E., Hartmann, E. and Koehler, M.
Biochimica et Biophysica Acta - Molecular Cell Research 1783
(3): 394-404.
March 2008
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide.
Feldt, S., Batenburg, W.W., Mazak, I., Maschke, U., Wellner, M., Kvakan, H., Dechend, R., Fiebeler, A., Burckle, C., Contrepas, A., Danser, A.H., Bader, M., Nguyen, G., Luft, F.C. and Mueller, D.N.
Hypertension 51
(3): 682-688.
March 2008
The role of kinin B(1) receptors in the nociception produced by peripheral protein kinase C activation in mice.
Ferreira, J., Triches, K.M., Medeiros, R., Cabrini, D.A., Mori, M.A.S., Pesquero, J.B., Bader, M. and Calixto, J.B.
Neuropharmacology 54
(3): 597-604.
March 2008
Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism.
Santos, S.H.S., Fernandes, L.R., Mario, E.G., Ferreira, A.V., Porto, L.C., Alvarez-Leite, J.I., Botion, L.M., Bader, M., Alenina, N. and Santos, R.A.
Diabetes 57
(2): 340-347.
1 February 2008
Changes in the brain serotonin satiety system in transgenic rats lacking brain angiotensinogen.
Voigt, J.P., Raasch, W., Hoertnagl, H., Bader, M., Fink, H. and Joehren, O.
Journal of Neuroendocrinology 20
(2): 182-187.
February 2008
Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension.
Fischer, R., Dechend, R., Qadri, F., Markovic, M., Feldt, S., Herse, F., Park, J.K., Gapelyuk, A., Schwarz, I., Zacharzowsky, U.B., Plehm, R., Safak, E., Heuser, A., Schirdewan, A., Luft, F.C., Schunck, W.H. and Mueller, D.N.
Hypertension 51
(2): 540-546.
February 2008
Endothelial dysfunction and elevated blood pressure in MAS gene-deleted mice.
Xu, P., Costa-Goncalves, A.C., Todiras, M., Rabelo, L.A., Sampaio, W.O., Moura, M.M., Santos, S.S., Luft, F.C., Bader, M., Gross, V., Alenina, N. and Santos, R.A.S.
Hypertension 51
(2): 574-580.
February 2008
Essential role of TM V and VI for binding the C-terminal sequences of Des-Arg-kinins.
Santos, E.L., de Picoli Souza, K., Cibrian-Uhalte, E., Oliveira, S.M., Bader, M., Costa-Neto, C.M., Oliveira, L. and Pesquero, J.B.
International Immunopharmacology 8
(2): 282-288.
February 2008
Protective actions of human tissue kallikrein gene in transgenic rat hearts.
Silva, J.A., Silva, M.R., Nascimento, J.W., Bader, M. and Pesquero, J.B.
International Immunopharmacology 8
(2): 267-270.
February 2008
Roles of the kallikrein/kinin system in the adaptive immune system.
Schulze-Topphoff, U., Prat, A., Bader, M., Zipp, F. and Aktas, O.
International Immunopharmacology 8
(2): 155-160.
February 2008
The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains.
Tenner, K., Qadri, F., Bert, B., Voigt, J.P. and Bader, M.
Neuroscience Letters 431
(1): 21-25.
24 January 2008
Post-infarct sympathetic hyperactivity differentially stimulates expression of tyrosine hydroxylase and norepinephrine transporter.
Parrish, D.C., Gritman, K., Van Winkle, D.M., Woodward, W.R., Bader, M. and Habecker, B.A.
American Journal of Physiology Heart and Circulatory Physiology 294
(1): H99-H106.
1 January 2008
The antithrombotic effect of angiotensin-(1-7) involves mas-mediated NO release from platelets.
Fraga-Silva, R.A., Pinheiro, S.V., Goncalves, A.C., Alenina, N., Bader, M. and Santos, R.A.
Molecular Medicine 14
(1-2): 28-35.
January 2008
Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor.
Batenburg, W.W., Krop, M., Garrelds, I.M., de Vries, R., de Bruin, R.J.A., Burckle, C.A., Mueller, D.N., Bader, M., Nguyen, G. and Danser, A.H.J.
Journal of Hypertension 25
(12): 2441-2453.
December 2007
The second life of the (pro)renin receptor.
Bader, M.
Journal of the Renin Angiotensin Aldosterone System 8
(4): 205-208.
December 2007
Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger.
Ifuku, M., Faerber, K., Okuno, Y., Yamakawa, Y., Miyamoto, T., Nolte, C., Merrino, V.F., Kitada, S., Iwamoto, T., Komuro, I., Wang, B., Cheung, G., Ishikawa, E., Ooboshi, H., Bader, M., Wada, K., Kettenmann, H. and Noda, M.
Journal of Neuroscience 27
(48): 13065-13073.
28 November 2007
A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5.
Duchene, J., Lecomte, F., Ahmed, S., Cayla, C., Pesquero, J., Bader, M., Perretti, M. and Ahluwalia, A.
Journal of Immunology 179
(7): 4849-4856.
1 October 2007
Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function.
Costa-Goncalves, A.C., Leite, R., Fraga-Silva, R.A., Pinheiro, S.V., Reis, A.B., Reis, F.M., Touyz, R.M., Webb, R.C., Alenina, N., Bader, M. and Santos, R.A.S.
American Journal of Physiology: Heart and Circulatory Physiology 293
(4): H2588-H2596.
1 October 2007
Dynamics of DNA-demethylation in early mouse and rat embryos developed in vivo and in vitro.
Zaitseva, I., Zaitsev, S., Alenina, N., Bader, M. and Krivokharchenko, A.
Molecular Reproduction and Development 74
(10): 1255-1261.
October 2007
Plasticity and impact of the central renin-angiotensin system during development of ethanol dependence.
Sommer, W.H., Rimondini, R., Marquitz, M., Lidstroem, J., Siems, W.E., Bader, M. and Heilig, M.
Journal of Molecular Medicine 85
(10): 1089-1097.
October 2007
Influence of human tryptophan hydroxylase 2 N- and C-terminus on enzymatic activity and oligomerization.
Tenner, K., Walther, D. and Bader, M.
Journal of Neurochemistry 102
(6): 1887-1894.
September 2007
Kinin B1 receptor participates in the control of cardiac function in mice.
Lauton-Santos, S., Guatimosim, S., Castro, C.H., Oliveira, F.A., Almeida, A.P., Dias-Peixoto, M.F., Gomes, M.A., Pessoa, P., Pesquero, J.L., Pesquero, J.B., Bader, M. and Cruz, J.S.
Life Sciences 81
(10): 814-822.
16 August 2007
Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis.
Nocito, A., Dahm, F., Jochum, W., Jang, J.H., Georgiev, P., Bader, M., Renner, E.L. and Clavien, P.A.
Gastroenterology 133
(2): 608-618.
August 2007
A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation.
Folkesson, R., Malkiewicz, K., Kloskowska, E., Nilsson, T., Popova, E., Bogdanovic, N., Ganten, U., Ganten, D., Bader, M., Winblad, B. and Benedikz, E.
Biochemical and Biophysical Research Communications 358
(3): 777-782.
6 July 2007
Differential role of kinin B1 and B2 receptors in ischemia-induced apoptosis and ventricular remodeling.
Yin, H., Chao, J., Bader, M. and Chao, L.
Peptides 28
(7): 1383-1389.
July 2007
Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation.
Bocciardi, R., Giorda, R., Buttgereit, J., Gimelli, S., Divizia, M.T., Beri, S., Garofalo, S., Tavella, S., Lerone, M., Zuffardi, O., Bader, M., Ravazzolo, R. and Gimelli, G.
Human Mutation 28
(7): 724-731.
July 2007
Functional rescue of a defective angiotensin II AT1 receptor mutant by the Mas protooncogene.
Santos, E.L., Reis, R.I., Silva, R.G., Shimuta, S.U., Pecher, C., Bascands, J.L., Schanstra, J.P., Oliveira, L., Bader, M., Paiva, A.C.M., Costa-Neto, C.M. and Pesqueroa, J.B,
Regulatory Peptides 141
(1-3): 159-167.
7 June 2007
Mice deficient for both kinin receptors are normotensive and protected from endotoxin- induced hypotension.
Cayla, C., Todiras, M., Iliescu, R., Saul, V.V., Gross, V., Pilz, B., Chai, G., Merino, V.F., Pesquero, J.B., Baltatu, O.C. and Bader, M.
FASEB Journal 21
(8): 1689-1698.
June 2007
Multichannel SQUID system with integrated magnetic shielding for magnetocardiography of mice.
Ackermann, R., Wiekhorst, F., Beck, A., Gutkelch, D., Ruede, F., Schnabel, A., Steinhoff, U., Drung, D., Beyer, J., Assmann, C., Trahms, L., Koch, H., Schurig, T., Fischer, R., Bader, M., Ogata, H. and Kado, H.
IEEE Transactions on Applied Superconductivity 17
(2): 827-830.
June 2007
Expression of an angiotensin-(1-7)-producing fusion protein in rats induced marked changes in regional vascular resistance.
Botelho-Santos, G.A., Sampaio, W.O., Reudelhuber, T.L., Bader, M., Campagnole-Santos, M.J. and Santos, R.A.
American Journal of Physiology Heart and Circulatory Physiology 292
(5): H2485-H2490.
1 May 2007
Alterations in gene expression in the testis of angiotensin-(17)-receptor Mas-deficient mice.
Xu, P., Santos, R.A.S., Bader, M. and Alenina, N.
Regulatory Peptides 138
(2-3): 51-55.
1 February 2007
Mass-spectrometric identification of a novel angiotensin peptide in human plasma.
Jankowski, V., Vanholder, R., van der Giet, M., Toelle, M., Karadogan, S., Gobom, J., Furkert, J., Oksche, A., Krause, E., Tran, T.N., Tepel, M., Schuchardt, M., Schlueter, H., Wiedon, A., Beyermann, M., Bader, M., Todiras, M., Zidek, W. and Jankowski, J.
Arteriosclerosis Thrombosis and Vascular Biology 27
(2): 297-302.
February 2007
Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice.
Nocito, A., Georgiev, P., Dahm, F., Jochum, W., Bader, M., Graf, R. and Clavien, P.A.
Hepatology 45
(2): 369-376.
February 2007
Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease.
Walther, T., Tschoepe, C., Sterner-Kock, A., Westermann, D., Heringer-Walther, S., Riad, A., Nikolic, A., Wang, Y., Ebermann, L., Siems, W.E., Bader, M., Shakibaei, M., Schultheiss, H.P. and Doerner, A.
Circulation 115
(3): 333-344.
23 January 2007
Large-scale mapping of mutations affecting zebrafish development.
Geisler, R., Rauch, G.J., Geiger-Rudolph, S., Albrecht, A., van Bebber, F., Berger, A., Busch-Nentwich, E., Dahm, R., Dekens, M.P., Dooley, C., Elli, A.F., Gehring, I., Geiger, H., Geisler, M., Glaser, S., Holley, S., Huber, M., Kerr, A., Kirn, A., Knirsch, M., Konantz, M., Kuechler, A.M., Maderspacher, F., Neuhauss, S.C., Nicolson, T., Ober, E.A., Praeg, E., Ray, R., Rentzsch, B., Rick, J.M., Rief, E., Schauerte, H.E., Schepp, C.P., Schoenberger, U., Schonthaler, H.B., Seiler, C., Sidi, S., Soellner, C., Wehner, A., Weiler, C. and Nuesslein-Volhard, C.
BMC Genomics 8
: 11.
9 January 2007
Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3β activation.
Li, H.J., Yin, H., Yao, Y.Y., Shen, B., Bader, M., Chao, L. and Chao, J.
Cardiovascular Research 73
(1): 130-142.
1 January 2007
Development of antithrombotic miniribozymes that target peripheral tryptophan hydroxylase.
Peter, J.U., Alenina, N., Bader, M. and Walther, D.J.
Molecular and Cellular Biochemistry 295
(1-2): 205-215.
January 2007
Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension.
Morecroft, I., Dempsie, Y., Bader, M., Walther, D.J., Kotnik, K., Loughlin, L., Nilsen, M. and Maclean, M.R.
Hypertension 49
(1): 232-236.
January 2007
Working memory deficits in transgenic rats overexpressing human adenosine A(2A) receptors in the brain.
Gimenez-Llort, L., Schiffmann, S.N., Shmidt, T., Canela, L., Camon, L., Wassholm, M., Canals, M., Terasmaa, A., Fernandez-Teruel, A., Tobena, A., Popova, E., Ferre, S., Agnati, L., Ciruela, F., Martinez, E., Scheel-Kruger, J., Lluis, C., Franco, R., Fuxe, K. and Bader, M.
Neurobiology of Learning Memory 87
(1): 42-56.
January 2007
Animal models for hypertension/blood pressure recording.
Plehm, R., Barbosa, M.E. and Bader, M.
Methods in Molecular Medicine 129
: 115-126.
2007
Effects of genetic deletion of angiotensin-(1-7) receptor Mas on cardiac function during ischemia/reperfusion in the isolated perfused mouse heart.
Castro, C.H., Santos, R.A., Ferreira, A.J., Bader, M., Alenina, N. and Almeida, A.P.
Life Sciences 80
(3): 264-268.
23 December 2006
Renal function in transgenic rats expressing an angiotensin-(1-7)-producing fusion protein.
Ferreira, A.J., Pinheiro, S.V.B., Castro, C.H., Silva, G.A.B., Simoes E Silva, A.C., Almeida, A.P., Bader, M., Rentzsch, B., Reudelhuber, T.L. and Santos, R.A.S.
Regulatory Peptides 137
(3): 128-133.
10 December 2006
In vitro fertilization of bovine oocytes in protein-free culture system.
Smetanina, I.G., Tatarinova, L.V. and Krivokharchenko, A.S.
Russian Journal of Developmental Biology 37
(6): 366-370.
December 2006
Cardiac function and remodeling is attenuated in transgenic rats expressing the human kallikrein-1 gene after myocardial infarction.
Koch, M., Spillmann, F., Dendorfer, A., Westermann, D., Altmann, C., Sahabi, M., van Linthout, S., Bader, M., Walther, T., Schultheiss, H.P. and Tschoepe, C.
European Journal of Pharmacology - Molecular Pharmacology Section 550
(1-3): 143-148.
21 November 2006
Enhanced isoproterenol-induced cardiac hypertrophy in transgenic rats with low brain angiotensinogen.
Campos, L.A., Iliescu, R., Fontes, M.A.P., Schlegel, W.P., Bader, M. and Baltatu, O.C.
American Journal of Physiology Heart and Circulatory Physiology 291
(5): H2371-H2376.
1 November 2006
Full-term development of rat after transfer of nuclei from two-cell stage embryos.
Popova, E., Bader, M. and Krivokharchenko, A.
Biology of Reproduction 75
(4): 524-530.
October 2006
Functional domains of human tryptophan hydroxylase 2 (hTPH2).
Carkaci-Salli, N., Flanagan, J.M., Martz, M.K., Salli, U., Walther, D.J., Bader, M. and Vrana, K.E.
Journal of Biological Chemistry 281
(38): 28105-28112.
22 September 2006
Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel.
Si, H., Heyken, W.T., Woelfle, S.E., Tysiac, M., Schubert, R., Grgic, I., Vilianovich, L., Giebing, G., Maier, T., Gross, V., Bader, M., de Wit, C., Hoyer, J. and Koehler, R.
Circulation Research 99
(5): 537-544.
1 September 2006
Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor Mas knockout mice.
Santos, R.A., Castro, C.H., Gava, E., Pinheiro, S.V., Almeida, A.P., de Paula, R.D., Cruz, J.S., Ramos, A.S., Rosa, K.T., Irigoyen, M.C., Bader, M., Alenina, N., Kitten, G.T. and Ferreira, A.J.
Hypertension 547
(5): 996-1002.
May 2006
Platelet-derived serotonin mediates liver regeneration.
Lesurtel, M., Graf, R., Aleil, B., Walther, D.J., Tian, Y., Jochum, W., Gachet, C., Bader, M. and Clavien, P.A.
Science 312
(5770): 104-107.
7 April 2006
Altered circadian rhythm reentrainment to light phase shifts in rats with low brain angiotensinogen.
Campos, L.A., Plehm, R., Cipolla-Neto, J., Bader, M. and Baltatu, O.C.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 290
(4): R1122-R1127.
1 April 2006
Diabetic endothelin B receptor-deficient rats develop severe hypertension and progressive renal failure.
Pfab, T., Thoene-Reineke, C., Theilig, F., Lange, I., Witt, H., Maser-Gluth, C., Bader, M., Stasch, J.P., Ruiz, P., Bachmann, S., Yanagisawa, M. and Hocher, B.
Journal of the American Society of Nephrology 17
(4): 1082-1089.
April 2006
Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function.
Araújo, R.C., Mori, M.A., Merino, V.F., Bascands, J.L., Schanstra, J.P., Zollner, R.L., Villela, C.A., Nakaie, C.R., Paiva, A.C., Pesquero, J.L., Bader, M. and Pesquero, J.B.
Biological Chemistry 387
(4): 431-436.
April 2006
Cardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B.
Langenickel, T.H., Buttgereit, J., Pagel-Langenickel, I., Lindner, M., Monti, J., Beuerlein, K., Al-Saadi, N., Plehm, R., Popova, E., Tank, J., Dietz, R., Willenbrock, R. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 103
(12): 4735-4740.
21 March 2006
Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress.
Donath, S., Li, P., Willenbockel, C., Al-Saadi, N., Gross, V., Willnow, T.E., Bader, M., Martin, U., Bauersachs, J., Wollert, K.C., Dietz, R. and von Harsdorf, R.
Circulation 113
(9): 1203-1212.
7 March 2006
Elevated blood pressure and heart rate in human renin receptor transgenic rats.
Burckle, C.A., Danser, A.H.J., Mueller, D.N., Garrelds, I.M., Gasc, J.M., Popova, E., Plehm, R., Peters, J., Bader, M. and Nguyen, G.
Hypertension 47
(3): 552-556.
March 2006
Specification and differentiation of serotonergic neurons.
Alenina, N., Bashammakh, S. and Bader, M.
Stem Cell Reviews 2
(1): 5-10.
March 2006
Genetically altered animal models in the kallikrein-kinin system.
Pesquero, J.B. and Bader, M.
Biological Chemistry 387
(2): 119-126.
9 February 2006
Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genes.
Bachvarov, D., Bachvarova, M., Koumangaye, R., Klein, J., Pesquero, J.B., Neau, E., Bader, M., Schanstra, J.P. and Bascands, J.L.
Biological Chemistry 387
(1): 15-22.
January 2006
Derivation, maintenance, and characterization of rat embryonic stem cells in vitro.
Schulze, M., Ungefroren, H., Bader, M. and Faendrich, F.
Methods in Molecular Biology 329
: 45-58.
2006
Strain differences in superovulatory response, embryo development and efficiency of transgenic rat production.
Popova, E., Bader, M. and Krivokharchenko, A.
Transgenic Research 14
(5): 729-738.
1 October 2005
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.
de Castro, C.H., Souza dos Santos, R.A., Ferreira, A.J., Bader, M., Alenina, N. and de Almeida, A.P.
Hypertension 46
(4): 937-942.
12 September 2005
Central angiotensin II controls alcohol consumption via its AT1 receptor.
Maul, B., Krause, W., Pankow, K., Becker, M., Gembardt, F., Alenina, N., Walther, T., Bader, M. and Siems, W.E.
FASEB Journal 19
(11): 1474-1481.
1 September 2005
The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of Mas-knockout mice.
Lemos, V.S., Silva, D.M., Walther, T., Alenina, N., Bader, M. and Santos, R.A.
Journal of Cardiovascular Pharmacology 46
(3): 274-279.
1 September 2005
Transgenic activation of the kallikrein-kinin system inhibits intramyocardial inflammation, endothelial dysfunction, and oxidative stress in experimental diabetic cardiomyopathy.
Tschoepe, C., Walther, T., Escher, F., Spillmann, F., Du, J., Altmann, C., Schimke, I., Bader, M., Sanchez-Ferrer, C.F., Schultheiss, H.P. and Noutsias, M.
FASEB Journal 19
(14): 2057-2059.
29 August 2005
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming.
Grohmann, M., Spada, F., Schermelleh, L., Alenina, N., Bader, M., Cardoso, M.C. and Leonhardt, H.
BMC Developmental Biology 5
: 18.
24 August 2005
Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation.
Zhao, Y., Foryst-Ludwig, A., Bruemmer, D., Culman, J., Bader, M., Unger, T. and Kintscher, U.
Journal of Neurochemistry 94
(5): 1395-1401.
30 June 2005
Molecular structure and transcriptional regulation by nuclear factor-kappaB of the mouse kinin B1 receptor gene.
Merino, V.F., Silva, J.A., Araújo, R.C., Avellar, M.C., Bascands, J.L., Schanstra, J.P., Paiva, A.C., Bader, M. and Pesquero, J.B.
Biological Chemistry 386
(6): 515-522.
1 June 2005
(+)-Norfenfluramine-induced arterial contraction is not dependent on endogenous 5-HT or 5-HTT.
Ni, W., Wilhelm, C.S., Bader, M., Murphy, D.L., Lookingland, K.J. and Watts, S.W.
Journal of Pharmacology and Experimental Therapeutics 314
(3): 953-960.
18 May 2005
Reduced nerve injury-induced neuropathic pain in kinin B1 receptor knock-out mice.
Ferreira, J., Beirith, A., Mori, M.A., Araújo, R.C., Bader, M., Pesquero, J.B. and Calixto, J.B.
Journal of Neuroscience 25
(9): 2405-2412.
2 March 2005
Absence of diabetic hyperalgesia in bradykinin B1 receptor-knockout mice.
Gabra, B.H., Merino, V.F., Bader, M., Pesquero, J.B. and Sirois, P.
Regulatory Peptides 127
(1-3): 245-248.
1 January 2005
Altered renal response to acute volume expansion in transgenic rats harboring the human tissue kallikrein gene.
Passaglio, K.T., Baltatu, O., Machado, R.P., Dos Reis, A.M., Pesquero, J.B., Bader, M. and Santos, R.A.
Regulatory Peptides 124
(1-3): 127-135.
1 January 2005
Autonomic control in rats with overactivity of tissue renin-angiotensin or kallikrein-kinin system.
Ribeiro, J.M., Santos, R.A., Pesquero, J.B., Bader, M. and Krieger, E.M.
Regulatory Peptides 129
(1-3): 155-159.
1 January 2005
Brain angiotensin and anxiety-related behavior: The transgenic rat TGR(ASrAOGEN)680.
Voigt, J.P., Hoertnagl, H., Rex, A., van Hove, L., Bader, M. and Fink, H.
Brain Research 1046
(1-2): 145-156.
1 January 2005
Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats.
Vaneckova, I., Skaroupkova, P., Dvorak, P., Certikova-Chabova, V., Tesar, V., Bader, M., Ganten, D. and Kramer, J.J.
Physiological Research 54
(1): 17-24.
1 January 2005
Is the kidney always the cause of hypertension? Distinct roles for the kidney and systemic tissues in blood pressure regulation by the Renin-Angiotensin system. J Clin Invest 115: 1092-1099, 2005.
Crowley, S., Gurley, S., Oliverio, M., Pazmino, A., Griffiths, R., Flannery, P., Spurney, R., Kim, H.S., Smithies, O., Le, T., Coffman, T., Boucher, J., Masri, B., Daviaud, D., Gesta, S., Guigne, C., Mazzucotelli, A., Castan-Laurell, I., Tack, I., Knibiehler, B., Carpene, C., Audigier, Y., Saulnier-Blache, J., Valet, P., Engeli, S., Boehnke, J., Gorzelniak, K., Janke, J., Schling, P., Bader, M., Luft, F.C. and Sharma, A.
Journal of the American Society of Nephrology 16
: 1525-1532.
1 January 2005
Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice.
Bachmann, S., Mutig, K., Bates, J., Welker, P., Geist, B., Gross, V., Luft, F.C., Alenina, N., Bader, M., Thiele, B.J., Prasadan, K., Raffi, H.S. and Kumar, S.
American Journal of Physiology Renal Physiology 288
(3): F559-F567.
1 January 2005
Role of the B1 kinin receptor in the regulation of cardiac function and remodeling after myocardial infarction.
Xu, J., Carretero, O.A., Sun, Y., Shesely, E.G., Rhaleb, N.E., Liu, Y.H., Liao, T.D., Yang, J.J., Bader, M. and Yang, X.P.
Hypertension 45
(4): 747-753.
1 January 2005
Roles of nitric oxide and oxidative stress in the regulation of blood pressure and renal function in prehypertensive Ren-2 transgenic rats.
Vaneckova, I., Kramer, H.J., Novotna, J., Kazdova, L., Opocensky, M., Bader, M., Ganten, D. and Cervenka, L.
Kidney and Blood Pressure Research 28
(2): 117-126.
1 January 2005
Transient inflammatory response induced by apoptotic cells is an important mediator of melanoma cell engraftment and growth.
Correa, M., Machado, J., Carneiro, C.R.W., Pesquero, J.B., Bader, M., Travassos, L.R., Chammas, R. and Jasiulionis, M.G.
International Journal of Cancer 114
(3): 356-363.
1 January 2005
Weight loss and the renin-angiotensin-aldosterone system.
Engeli, S., Boehnke, J., Gorzelniak, K., Janke, J., Schling, P., Bader, M., Luft, F.C. and Sharma, A.M.
Hypertension 45
: 356-362.
1 January 2005
Complex narrow band-pass filters for QRS detection in contactless magnetocardiograms of small animals.
Steinhoff, U., Link, A., Wiekhorst, F., Bader, M., Knappe-Grueneberg, S. and Ackermann, R.
Computers in Cardiology 32
: 467-470.
2005
Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney.
Pinheiro, S.V.B., Simoes e Silva, A.C., Sampaio, W.O., de Paula, R.D., Mendes, E.P., Bontempo, E.D., Pesquero, J.B., Walther, T., Alenina, N., Bader, M., Bleich, M. and Santos, R.A.S.
Hypertension 44
(4): 490-496.
1 October 2004
Improvement of defective sarcoplasmic reticulum Ca2+ transport in diabetic heart of transgenic rats expressing the human kallikrein-1 gene.
Tschoepe, C., Spillmann, F., Rehfeld, U., Koch, M., Westermann, D., Altmann, C., Dendorfer, A., Walther, T., Bader, M., Paul, M., Schultheiss, H.P. and Vetter, R.
FASEB Journal 18
(15): 1967-1969.
24 September 2004
Genetic targeting of the brain renin-angiotensin system in transgenic rats: Impact on stress-induced renin release.
Baltatu, O., Campos, L.A. and Bader, M.
Acta Physiologica Scandinavica 181
(4): 579-584.
1 August 2004
Differential regulation of central vasopressin receptors in transgenic rats with low brain angiotensinogen.
Campos, L.A., Couto, A.S., Iliescu, R., Santos, J.A., Santos, R.A.S., Ganten, D., Campagnole-Santos, M.J., Bader, M. and Baltatu, O.
Regulatory Peptides 119
(3): 177-182.
15 July 2004
Prevention of cardiac fibrosis and left ventricular dysfunction in diabetic cardiomyopathy in rats by transgenic expression of the human tissue kallikrein gene.
Tschoepe, C., Walther, T., Koeniger, J., Spillmann, F., Westermann, D., Escher, F., Pauschinger, M., Pesquero, J.B., Bader, M., Schultheiss, H.P. and Noutsias, M.
FASEB Journal 18
(7): 828-835.
May 2004
Plasma and kidney angiotensin II levels and renal functional responses to AT1 receptor blockade in hypertensive Ren-2 transgenic rats.
Kopkan, L., Kramer, H.J., Huskova, Z., Vanourkova, Z., Baecker, A., Bader, M., Ganten, D. and Cervenka, L.
Journal of Hypertension 22
(4): 819-825.
1 April 2004
Forced homodimerization by site-directed mutagenesis alters guanylyl cyclase activity of natriuretic peptide receptor B.
Langenickel, T., Buttgereit, J., Pagel, I., Dietz, R., Willenbrock, R. and Bader, M.
Hypertension 43
(2): 460-465.
February 2004
Acute effects of cyclooxygenase-2 inhibition on renal function in heterozygous Ren-2-transgenic rats on normal or low sodium intake.
Vaneckova, I., Cahova, M., Kramer, H.J., Huskova, Z., Skaroupkova, P., Komers, R., Bader, M., Ganten, D. and Cervenka, L.
Kidney and Blood Pressure Research 27
(4): 203-210.
1 January 2004
Blockade of endothelin receptors attenuates end-organ damage in homozygous hypertensive Ren-2 transgenic rats.
Dvorak, P., Kramer, H.J., Baecker, A., Maly, J., Kopkan, L., Vaneckova, I., Vernerova, Z., Opocensky, M., Tesar, V., Bader, M., Ganten, D., Janda, J. and Cervenka, L.
Kidney and Blood Pressure Research 27
(4): 248-258.
1 January 2004
Bradykinin B1 receptor expression induced by tissue damage in the rat portal vein - A critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways.
Medeiros, R., Cabrini, D.A., Ferreira, J., Fernandes, E.S., Mori, M.A.S., Pesquero, J.B., Bader, M., Avellar, M.C.W., Campos, M.M. and Calixto, J.B.
Circulation Research 94
(10): 1375-1382.
1 January 2004
Chronic endothelin receptor blockade reduces end-organ damage independently of blood pressure effects in salt-loaded heterozygous Ren-2 transgenic rats.
Opocensky, M., Dvorak, P., Maly, J., Kramer, H.J., Baecker, A., Kopkan, L., Vernerova, Z., Tesar, V., Zima, T., Bader, M., Ganten, D., Janda, J. and Vaneckova, I.
Physiological Research 53
(6): 581-593.
1 January 2004
Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.
Ciruela, F., Burgueno, J., Casado, V.V., Canals, M., Marcellino, D., Goldberg, S.R., Bader, M., Fuxe, K., Agnati, L.F., Lluis, C., Franco, R., Ferre, S. and Woods, A.S.
Analytical Chemistry 76
(18): 5354-5363.
1 January 2004
Efficiency of transgenic rat production is independent of transgene-construct and overnight embryo culture.
Popova, E., Krivokharchenko, A., Ganten, D. and Bader, M.
Theriogenology 61
(7-8): 1441-1453.
1 January 2004
Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in rats.
Santos, R.A.S., Ferreira, A.J., Nadu, A.P., Braga, A.N.G., de Almeida, A.P., Campagnole-Santos, M.J., Baltatu, O., Iliescu, R., Reudelhuber, T.L. and Bader, M.
Physiological Genomics 17
(3): 292-299.
1 January 2004
Functional characterization of the human atrial essential myosin light chain (hALC-1) in a transgenic rat model.
Abdelaziz, A.I., Segaric, J., Bartsch, H., Petzhold, D., Schlegel, W., Kott, M., Seefeldt, I., Klose, J., Bader, M., Haase, H. and Morano, I.
Journal of Molecular Medicine 82
(4): 265-274.
1 January 2004
Mouse Ahnak (desmoyokin) homologous to human AHNAK [Accession: AY369977 / Locus: AY367634S2 / Organism: Mus musculus (house mouse)].
Petzhold, D., Bader, M., Bartsch, H., Hohaus, A., Morano, I. and Haase, H.
Nucleotide (GenBank)
1 January 2004
Rat corin gene: molecular cloning and reduced expression in experimental heart failure.
Langenickel, T.H., Pagel, I., Buttgereit, J., Tenner, K., Lindner, M., Dietz, R., Willenbrock, R. and Bader, M.
American Journal of Physiology Heart and Circulatory Physiology 287
(4): H1516-H1521.
1 January 2004
Role of bradykinin B2 and B1 receptors in the local, remote, and systemic inflammatory responses that follow intestinal ischemia and reperfusion injury.
Souza, D.G., Lomez, E.S.L., Pinho, V., Pesquero, J.B., Bader, M., Pesquero, J.L. and Teixeira, M.M.
Journal of Immunology 172
(4): 2542-2548.
1 January 2004
Role of kinin B1 and B2 receptors in the development of pilocarpine model of epilepsy.
Arganaraz, G.A., Perosa, S.R., Lencioni, E.C., Bader, M., Cavalheiro, E.A., da Graca Naffah-Mazzacoratti, M., Pesquero, J.B. and Silva, J.A.
Brain Research 1013
(1): 30-39.
1 January 2004
Serotonin regulates mammary gland development via an autocrine-paracrine loop.
Matsuda, M., Imaoka, T., Vomachka, A.J., Gudelsky, G.A., Hou, Z.Y., Mistry, M., Bailey, J.P., Nieport, K.M., Walther, D.J., Bader, M. and Horseman, N.D.
Developmental Cell 6
(2): 193-203.
1 January 2004
Structure and expression of two kininogen genes in mice.
Cardoso, C.C., Garrett, T., Cayla, C., Meneton, P., Pesquero, J.B. and Bader, M.
Biological Chemistry 385
(3-4): 295-301.
1 January 2004
The synthesis and distribution of the kinin B1 and B2 receptors are modified in the hippocampus of rats submitted to pilocarpine model of epilepsy.
Arganaraz, G.A., Silva, J.A., Perosa, S.R., Pessoa, L.G., Carvalho, F.F., Bascands, J.L., Bader, M., Trindade, E.D., Amado, D., Cavalheiro, E.A., Pesquero, J.B. and Naffah-Mazzacoratti, M.D.
Brain Research 1006
(1): 114-125.
1 January 2004
Uncoupling protein 3 as a mitochondrial fatty acid anion exporter.
Schrauwen, P., Hoeks, J., Schaart, G., Kornips, E., Binas, B., van de Vusse, G.J., van Bilsen, M., Luiken, J.J.F.P., Coort, S.L.M., Glatz, J.F.C., Saris, W.H.M. and Hesselinkt, M.K.C.
FASEB Journal 17
(15): 2272-2274.
December 2003
A unique central tryptophan hydroxylase isoform.
Walther, D.J. and Bader, M.
Biochemical Pharmacology 66
(9): 1673-1680.
1 November 2003
Brain renin-angiotensin system - Lessons from functional genomics.
Baltatu, O. and Bader, M.
Neuroendocrinology 78
(5): 253-259.
November 2003
Cytoplasmic fatty acid-binding protein facilitates fatty acid utilization by skeletal muscle.
Glatz, J.F.C., Schaap, F.G., Binas, B., Bonen, A., van der Vusse, G.J. and Luiken, J.J.F.P.
Acta Physiologica Scandinavica 178
(4): 367-371.
August 2003
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas.
Santos, R.A.S., e Silva, A.C.S., Maric, C., Silva, D.M.R., Machado, R.P., de Buhr, I., Heringer-Walther, S., Pinheiro, S.V.B., Lopes, M.T., Bader, M., Mendes, E.P., Lemos, V.S., Campagnole-Santos, M.J., Schultheiss, H.P., Speth, R. and Walther, T.
Proceedings of the National Academy of Sciences of the United States of America 100
(14): 8258-8263.
8 July 2003
Androgen receptor independent cardiovascular action of the antiandrogen flutamide.
Iliescu, R., Campos, L.A., Schlegel, W.P., Morano, I., Baltatu, O. and Bader, M.
Journal of Molecular Medicine 81
(7): 420-427.
July 2003
Long-term culture and differentiation of rat embryonic stem cell-like cells into neuronal, glial, endothelial, and hepatic lineages.
Ruhnke, M., Ungefroren, H., Zehle, G., Bader, M., Kremer, B. and Fandrich, F.
Stem Cells 21
(4): 428-436.
July 2003
Tonin in rat heart with experimental hypertrophy.
Borges, J.C., Silva, J.A., Gomes, M.A., Lomez, E.S.L., Leite, K.M., Araujo, R.C., Bader, M., Pesquero, J.B. and Pesquero, J.L.
American Journal of Physiology Heart and Circulatory Physiology 284
(6): H2263-H2268.
1 June 2003
The vesicular monoamine content regulates VMAT2 activity through G α(q) mouse platelets - evidence for autoregulation of vesicular transmitter update.
Holtje, M., Winter, S., Walther, D., Pahner, I., Hortnagl, H., Ottersen, O.P., Bader, M. and Ahnert-Hilger, G.
Journal of Biological Chemistry 278
(18): 15850-15858.
2 May 2003
Transgenic rat model of Huntington's disease.
von Hoersten, S., Schmitt, I., Nguyen, H.P., Holzmann, C., Schmidt, T., Walther, T., Bader, M., Pabst, R., Kobbe, P., Krotova, J., Stiller, D., Kask, A., Vaarmann, A., Rathke-Hartlieb, S., Schulz, J.B., Grasshoff, U., Bauer, I., Vieira-Saecker, A.M.M., Paul, M., Jones, L., Lindenberg, K.S., Landwehrmeyer, B., Bauer, A., Li, X.J. and Riess, O.
Human Molecular Genetics 12
(6): 617-624.
15 March 2003
Development of parthenogenetic rat embryos.
Krivokharchenko, A., Popova, E., Zaitseva, I., Vil'ianovich, L., Ganten, D. and Bader, M.
Biology of Reproduction 68
(3): 829-836.
1 March 2003
Abolition of end-organ damage by antiandrogen treatment in female hypertensive transgenic rats.
Baltatu, O., Cayla, C., Iliescu, R., Andreev, D. and Bader, M.
Hypertension 41
(3): 830-833.
March 2003
Synthesis of serotonin by a second tryptophan hydroxylase isoform.
Walther, D.J., Peter, J.U., Bashammakh, S., Hoertnagl, H., Voits, M., Fink, H. and Bader, M.
Science 299
(5603): 76-76.
3 January 2003
Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene.
Martin, G.G., Danneberg, H., Kumar, L.S., Atshaves, B.P., Erol, E., Bader, M., Schroeder, F. and Binas, B.
Journal of Biological Chemistry 278
(24): 21429-21438.
1 January 2003
Delayed maturation of catecholamine phenotype in nucleus tractus solitarius of rats with glial angiotensinogen depletion.
Ogier, M., Bezin, L., Cottet-Emard, J.M., Bader, M., Vincent, M., Pequignot, J.M., McGregor, J. and Bricca, G.
Hypertension 42
(5): 978-984.
1 January 2003
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet α-granule release.
Walther, D.J., Peter, J.U., Winter, S., Hoeltje, M., Paulmann, N., Grohmann, M., Vowinckel, J., Alamo-Bethencourt, V., Wilhelm, C.S., Ahnert-Hilger, G. and Bader, M.
Cell 115
(7): 851-862.
1 January 2003
Trypanosoma cruzi induces edematogenic responses in mice and invades cardiomyocytes and endothelial cells in vitro by activating distinct kinin receptor subtypes (B-1/B-2).
Todorov, A.G., Andrade, D., Pesquero, J.B., de Carvalho Araujo, R., Bader, M., Stewart, J., Gera, L., Mueller-Esterl, W., Morandi, V., Goldenberg, R.C.S., Neto, H.C.F. and Scharfstein, J.
FASEB Journal 17
(1): U371-U392.
January 2003
Transcriptional regulation of the rat bradykinin B2 receptor gene: Identification of a silencer element.
Baptista, H.A., Avellar, M.C.W., Araujo, R.C., Pesquero, J.L., Schanstra, J.P., Bascands, J.L., Esteve, J.P., Paiva, A.C.M., Bader, M. and Pesquero, J.B.
Molecular Pharmacology 62
(6): 1344-1355.
1 December 2002
Structure of the mammalian kinin receptor gene locus.
Cayla, C., Merino, V.F., Cabrini, D.A., Silva, J.A., Pesquero, J.B. and Bader, M.
International Immunopharmacology 2
(13-14): 1721-1727.
December 2002
The use of kinin B1 and B2 receptor knockout mice and selective antagonists to characterize the nociceptive responses caused by kinins at the spinal level.
Ferreira, J., Campos, M.M., Araújo, R., Bader, M., Pesquero, J.B. and Calixto, J.B.
Neuropharmacology 43
(7): 1188-1197.
December 2002
Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse Ren-2 gene.
Baltatu, O., Cayla, C., Iliescu, R., Andreev, D., Jordan, C. and Bader, M.
Journal of the American Society of Nephrology 13
(11): 2681-2687.
1 November 2002
Role of the local renin-angiotensin system in cardiac damage: a minireview focussing on transgenic animal models.
Bader, M.
Journal of Molecular and Cellular Cardiology 34
(11): 1455-1462.
November 2002
Comparison between PMSG- and FSH-induced superovulation for the generation of transgenic rats.
Popova, E., Krivokharchenko, A., Ganten, D. and Bader, M.
Molecular Reproduction and Development 63
(2): 177-182.
October 2002
Proteomic analysis reveals alterations in the renal kallikrein pathway during hypoxia-induced hypertension.
Thongboonkerd, V., Gozal, E., Sachleben, L.R., Arthur, J.M., Pierce, W.M., Cai, J., Chao, J., Bader, M., Pesquero, J.B., Gozal, D. and Klein, J.B.
Journal of Biological Chemistry 277
(38): 34708-34716.
20 September 2002
In vivo bradykinin B2 receptor activation reduces renal fibrosis.
Schanstra, J.P., Neau, E., Drogoz, P., Gomez, M.A.A., Novoa, J.M.L., Calise, D., Pecher, C., Bader, M., Girolami, J.P. and Bascands, J.L.
Journal of Clinical Investigation 110
(3): 371-379.
1 August 2002
Tonin expression in the rat brain and tonin-mediated central production of angiotensin II.
Araujo, R.C., Lima, M.P., Lomez, E.S.L., Bader, M., Pesquero, J.B., Sumitani, M. and Pesquero, J.L.
Physiology & Behavior 76
(2): 327-333.
1 June 2002
Reduced hypertension-induced end-organ damage in mice lacking cardiac and renal angiotensinogen synthesis.
Kang, N.L., Walther, T., Tian, X.L., Bohlender, J., Fukamizu, A., Ganten, D. and Bader, M.
Journal of Molecular Medicine 80
(6): 359-366.
June 2002
Cell type-specific expression of the Mas proto-oncogene in testis.
Alenina, N., Baranova, T., Smirnow, E., Bader, M., Lippoldt, A., Patkin, E. and Walther, T.
Journal of Histochemistry & Cytochemistry 50
(5): 691-695.
May 2002
Detrimental implication of B-1 receptors in myocardial ischemia: evidence from pharmacological blockade and gene knockout mice.
Lagneux, C., Bader, M., Pesquero, J.B., Demenge, P. and Ribuot, C.
International Immunopharmacology 2
(6): 815-822.
May 2002
Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen.
Couto, A.S., Baltatu, O., Santos, R.A.S., Ganten, D., Bader, M. and Campagnole-Santos, M.J.
Journal of Hypertension 20
(5): 919-925.
May 2002
Blood pressure response to chronic episodic hypoxia: the renin-angiotensin system.
Fletcher, E.C., Orolinova, N. and Bader, M.
Journal of Applied Physiology 92
: 627-633.
1 February 2002
Preimplantation-stage stem cells induce long-term allogeneic graft acceptance without supplementary host conditioning.
Faendrich, F., Lin, X., Chai, G.X., Schulze, M., Ganten, D., Bader, M., Holle, J., Huang, D.S., Parwaresch, R., Zavazava, N. and Binas, B.
Nature Medicine 8
: 171-178.
1 February 2002
Ischemic injury in experimental stroke depends on angiotensin II.
Walther, T., Olah, L., Harms, C., Maul, B., Bader, M., Hoertnagl, H., Schultheiss, H.P. and Mies, G.
FASEB Journal 16
(2): 169-176.
February 2002
Targeting kinin B1 receptor for therapeutic neovascularization.
Emanueli, C., Salis, M.B., Stacca, T., Pintus, G., Kirchmair, R., Isner, J.M., Pinna, A., Gaspa, L., Regoli, D., Cayla, C., Pesquero, J.B., Bader, M. and Madeddu, P.
Circulation 105
: 360-366.
22 January 2002
7-hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors.
Walther, D.J., Peter, J.U. and Bader, M.
Cance 94
(12): 3135-3140.
1 January 2002
Imprinting of the murine Mas protooncogene is restricted to its antisense RNA.
Alenina, N., Bader, M. and Walther, T.
Biochemical and Biophysical Research Communications 290
: 1072-1078.
1 January 2002
In vitro formation of tetraploid rat blastocysts after fusion of two-cell embryos.
Krivokharchenko, A., Galat, V., Ganten, D. and Bader, M.
Molecular Reproduction and Development 61
(4): 460-465.
1 January 2002
Locally synthesized angiotensin modulates pineal melatonin generation.
Baltatu, O., Afeche, S.C., dos Santos, S.H.J., Campos, L.A., Barbosa, R., Michelini, L.C., Bader, M. and Cipolla-Neto, J.
Journal of Neurochemistry 80
(2): 328-334.
1 January 2002
Molecular structure and alternative splicing of the human carboxypeptidase M gene.
Pessoa, L.G., da Silva, I.D.G., Baptista, H.A., Pesquero, J.L., Paiva, A.C.M., Bader, M. and Pesquero, J.B.
Biological Chemistry 383
: 263-269.
1 January 2002
Tonin and kallikrein in the brain of transgenic rat line expressing human tissue kallikrein.
Lomez, E.S.L., Araujo, R.C., Bader, M., Pesquero, J.B. and Pesquero, J.L.
Hypertension 39
: 229-232.
1 January 2002
Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
Cervenka, L., Kramer, H.J., Maly, J., Vaneckova, I., Baecker, A., Bokemeyer, D., Bader, M., Ganten, D. and Mitchell, K.D.
Physiological Research 51
(6): 571-580.
2002
Evidence for the participation of kinins in Freund's adjuvant-induced inflammatory and nociceptive responses in kinin B1 and B2 receptor knockout mice.
Ferreira, J., Campos, M.M., Pesquero, J.B., Araújo, R.C., Bader, M. and Calixto, J.B.
Neuropharmacology 41
(8): 1006-1012.
1 December 2001
Alcohol consumption is controlled by angiotensin II.
Maul, B., Siems, W.E., Hoehe, M.R., Grecksch, G., Bader, M. and Walther, T.
FASEB Journal 15
: 1640-1642.
1 July 2001
Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen.
Baltatu, O., Janssen, B.J., Bricca, G., Plehm, R., Monti, J., Ganten, D. and Bader, M.
Hypertension 37
(2): 408-413.
1 January 2001
Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen.
Baltatu, O., Fontes, M.A.P., Campagnole-Santos, M.J., Caligiorni, S., Ganten, D., Santos, R.A.S. and Bader, M.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 280
(2): R428-R433.
1 January 2001
Altered neutrophil homeostasis in kinin B1 receptor deficient mice.
Araújo, R.C., Kettritz, R., Fichtner, I., Paiva, A.C.M., Pesquero, J.B. and Bader, M.
Biological Chemistry 382
: 91-95.
1 January 2001
Genetic deletion of angiotensin AT2 receptor leads to increased cell numbers in different brain structures of mice.
Halbach, O.V.U., Walther, T., Bader, M. and Albrecht, D.
Regulatory Peptides 99
: 209-216.
1 January 2001
Gestational regulation of the gene expression of C-type natriuretic peptide in mouse reproductive and embryonic tissue.
Stepan, H., Leitner, E., Walter, K., Bader, M., Schultheiss, H.P., Faber, R. and Walther, T.
Regulatory Peptides 102
(1): 9-13.
1 January 2001
Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).
Monti, J., Schinke, M., Boehm, M., Ganten, D., Bader, M. and Bricca, G.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 280
(1): R233-R240.
1 January 2001
Induction of hippocampal glial cells expressing basic fibroblast growth factor RNA by corticosterone.
Hansson, A.C., Sommer, W., Andbjer, B., Bader, M., Ganten, D. and Fuxe, K.
NeuroReport 12
(1): 141-145.
1 January 2001
Interactions between angiotensin-(1-7), kinins, and angiotensin II in kidney and blood vessels.
dos Santos, R.A.S., Passaglio, K.T., Pesquero, J.B., Bader, M. and Silva, A.C.S.E.
Hypertension 38
: 660-664.
1 January 2001
Molecular interactions of vasoactive systems in cardiovascular damage.
Bader, M.
Journal of Cardiovascular Pharmacology 38
(2): S7-S9.
1 January 2001
Normal blood pressure and renal function in mice lacking the bradykinin B2 receptor.
Milia, A.F., Gross, V., Plehm, R., De Silva, J.A., Bader, M. and Luft, F.C.
Hypertension 37
: 1473-1479.
1 January 2001
Physiological and genomic consequences of intermittent hypoxia - Selected contribution: Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats.
Tahawi, Z., Orolinova, N., Joshua, I.G., Bader, M. and Fletcher, E.C.
Journal of Applied Physiology 90
: 2007-2013.
1 January 2001
Deletion of the gene encoding H-FABP/MDGI has no overt effects in the mammary gland.
Clark, A.J., Neil, C., Gusterson, B., McWhir, J. and Binas, B.
Transgenic Research 9
(6): 439-444.
1 December 2000
Organ-specific mRNA distribution of C-type natriuretic peptide in neonatal and adult mice.
Stepan, H., Leitner, E., Bader, M. and Walther, T.
Regulatory Peptides 95
(1-3): 81-85.
24 November 2000
Baroreflex sensitivity, heart rate, and blood pressure variability in normal pregnancy.
Voss, A., Malberg, H., Schumann, A., Wessel, N., Walther, T., Stepan, H. and Faber, R.
American Journal of Hypertension 13
(11): 1218-1225.
November 2000
Increased kallikrein expression protects against cardiac ischemia.
Pinto, Y.M., Bader, M., Pesquero, J.B., Tschoepe, C., Scholtens, E., van Gilst, W.H. and Buikema, H.
FASEB Journal 14
(13): 1861-1863.
1 October 2000
Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene.
Silva, J.A., Araujo, R.C., Baltatu, O., Oliveira, S.M., Tschoepe, C., Fink, E., Hoffmann, S., Plehm, R., Chai, K.X., Chao, L., Chao, J., Ganten, D., Pesquero, J.B. and Bader, M.
FASEB Journal 14
(13): 1858-1860.
1 October 2000
Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat.
Hansson, A.C., Cintra, A., Belluardo, N., Sommer, W., Bhatnagar, M., Bader, M., Ganten, D. and Fuxe, K.
European Journal of Neuroscience 12
(8): 2918-2934.
1 August 2000
Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors.
Pesquero, J.B., Araujo, R.C., Heppenstall, P.A., Stucky, C.L., Silva, J.A., Walther, T., Oliveira, S.M., Pesquero, J.L., Paiva, A.C.M., Calixto, J.B., Lewin, G.R. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 97
(14): 8140-8145.
5 July 2000
Regulation of the kinin receptors after induction of myocardial infarction: a mini-review.
Tschoepe, C., Heringer-Walther, S. and Walther, T.
Brazilian Journal of Medical and Biological Research 33
(6): 701-708.
1 June 2000
Smooth-muscle contraction without smooth-muscle myosin.
Morano, I., Chai, G.X., Baltas, L.G., Lamounier-Zepter, V., Lutsch, G., Kott, M., Haase, H. and Bader, M.
Nature Cell Biology 2
(6): 371-375.
1 June 2000
Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
Fontes, M.A.P., Baltatu, O., Caligiorne, S.M., Campagnole-Santos, M.J., Ganten, D., Bader, M. and Santos, R.A.S.
Physiological Genomics 2
: 137-142.
27 April 2000
Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation.
Brandt, R., Eisenbrandt, R., Leenders, F., Zschiesche, W., Binas, B., Juergensen, C. and Theuring, F.
Oncogene 19
: 2129-2137.
20 April 2000
Interaction between Mas and the angiotensin AT1 receptor in the amygdala.
Halbach, O.V.U., Walther, T., Bader, M. and Albrecht, D.
Journal of Neurophysiology 83
(4): 2012-2021.
1 April 2000
Upregulation of bradykinin B1-receptor expression after myocardial infarction.
Tschoepe, C., Heringer-Walther, S., Koch, M., Spillmann, F., Wendorf, M., Leitner, E., Schultheiss, H.P. and Walther, T.
British Journal of Pharmacology 129
(8): 1537-1538.
1 April 2000
Cutaneous inflammation and proliferation in vitro: Differential effects and mode of action of topical glucocorticoids.
Lange, K., Kleuser, B., Gysler, A., Bader, M., Maia, C., Scheidereit, C., Korting, H.C. and Schaefer-Korting, M.
Skin Pharmacology and Applied Skin Physiology 13
(2): 93-103.
1 March 2000
Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Mervaalo, E., Mueller, D.N., Schmidt, F., Park, J.K., Gross, V., Bader, M., Breu, V., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 35
(2): 587-594.
1 February 2000
Myocardial bradykinin B2-receptor expression at different time points after induction of myocardial infarction.
Tschoepe, C., Heringer-Walther, S., Koch, M., Spillmann, F., Wendorf, M., Hauke, D., Bader, M., Schultheiss, H.P. and Walther, T.
Journal of Hypertension 18
(2): 223-228.
1 February 2000
Inhibition of pressure natriuresis in mice lacking the AT2 receptor.
Gross, V., Schunck, W.H., Honeck, H., Milia, A.F., Kaergel, E., Walther, T., Bader, M., Inagami, T., Schneider, W. and Luft, F.C.
Kidney International 57
: 191-202.
29 January 2000
Altered heart rate and blood pressure variability in mice lacking the Mas protooncogene.
Walther, T., Wessel, N., Kang, N., Sander, A., Tschoepe, C., Malberg, H., Bader, M. and Voss, A.
Brazilian Journal of Medical and Biological Research 33
(1): 1-9.
1 January 2000
Assignment of the kinin receptor B1 and B2 genes (Bdkrb1 and Bdkrb2) to rat chromosome 6q3.2 by FISH and radiation hybrid mapping.
Goesele, C., Gruetzner, F., Pesquero, J.B., Silva, J.A., Junge, T., Ganten, D., Bader, M. and Knoblauch, M.
Cytogenetics and Cell Genetics 89
(1-2): 51-52.
1 January 2000
Detection of C-type natriuretic peptide in fetal circulation.
Stepan, H., Walther, D., Faber, R. and Walther, T.
Journal of Perinatal Medicine 28
(2): 118-121.
1 January 2000
From genotype to phenotype--behavior of the transgenic rat TGR(mRen2)27 as an example.
Voigt, J.P., Rex, A., Bader, M. and Fink, H.
Reviews in the Neurosciences 11
: 37-45.
1 January 2000
Sex specific behavioural alterations in Mas-deficient mice.
Walther, T., Voigt, J.P., Fink, H. and Bader, M.
Behavioural Brain Research 107
(1-2): 105-109.
1 January 2000
The brain renin-angiotensin system modulates angiotensin II-induced hypertension and cardiac hypertrophy.
Baltatu, O., Silva, J.A., Ganten, D. and Bader, M.
Hypertension 35
(1): 409-412.
1 January 2000
Transgenic animal models for neuropharmacology.
Bader, M.
Reviews in the Neurosciences 11
(1): 27-36.
1 January 2000
Functional, biochemical, and molecular investigations of renal kallikrein-kinin system in diabetic rats.
Tschoepe, C., Reinecke, A., Seidl, U., Yu, M., Gavriluk, V., Riester, U., Gohlke, P., Graf, K., Bader, M., Hilgenfeldt, U., Pesquero, J.B., Ritz, E. and Unger, T.
American Journal of Physiology Heart and Circulatory Physiology 277
(6 Pt 2): H2333-H2340.
December 1999
Myocardial expression of rat bradykinin receptors and two tissue kallikrein genes in experimental diabetes.
Tschoepe, C., Walther, T., Yu, M., Reinecke, A., Koch, M., Seligmann, C., Heringer, S.B., Pesquero, J.B., Bader, M., Schultheiss, H.P. and Unger, T.
Immunopharmacology 44
(1-2): 35-42.
15 October 1999
Upregulation of the cardiac bradykinin B2 receptors after myocardial infarction.
Tschoepe, C., Koch, M., Spillmann, F., Heringer-Walther, S., Mochmann, H.C., Stauss, H., Bader, M., Unger, T., Schultheiss, H.P. and Walther, T.
Immunopharmacology 44
(1-2): 111-117.
15 October 1999
mRNA quantification of C-type natriuretic peptide in brain areas of rodents.
Stepan, H., Leitner, E., Siems, W.E., Maul, B. and Walther, T.
Peptides 20
: 1243-1245.
1 October 1999
Larger anastomoses in angiotensinogen-knockout mice attenuate early metabolic disturbances after middle cerebral artery occlusion.
Maeda, K., Hata, R., Bader, M., Walther, T. and Hossmann, K.A.
Journal of Cerebral Blood Flow and Metabolism 19
(10): 1092-1098.
October 1999
Impaired long-chain fatty acid utilization by cardiac myocytes isolated from mice lacking the heart-type fatty acid binding protein gene.
Schaap, F.G., Binas, B., Danneberg, H., van der Vusse, G.J. and Glatz, J.F.C.
Circulation Research 85
: 329-337.
20 August 1999
Serotonin synthesis in murine embryonic stem cells.
Walther, D.J. and Bader, M.
Molecular Brain Research 68
: 55-63.
7 May 1999
Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization.
Binas, B., Danneberg, H., McWhir, J., Mullins, L. and Clark, A.J.
FASEB Journal 13
(8): 805-812.
May 1999
Learning and anxiety in angiotensin-deficient mice.
Walther, T., Voigt, J.P., Fukamizu, A., Fink, H. and Bader, M.
Behavioural Brain Research 100
: 1-4.
1 April 1999
Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.
Schinke, M., Baltatu, O., Boehm, M., Peters, J., Rascher, W., Bricca, G., Lippoldt, A., Ganten, D. and Bader, M.
Proceedings of the National Academy of Sciences of the United States of America 96
: 3975-3980.
30 March 1999
An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D-3.
Nykjaer, A., Dragun, D., Walther, D., Vorum, H., Jacobsen, C., Herz, J., Melsen, F., Christensen, E.I. and Willnow, T.E.
Cell 96
(4): 507-515.
19 February 1999
C-type natriuretic peptide levels in women with gestational hypertension and preeclampsia.
Stepan, H., Faber, R., Walther, D. and Walther, T.
Obstetrics and Gynecology 93
: 199-202.
1 February 1999
Obnaruzhenie transgennykh zhivotnykh pri pomoshchi polimeraznoi tsepnoi reaktsii in situ. [The detection of transgenic animals using a polymerase chain reaction in situ].
Popov, A.V., Golubkov, V.I., Smirnov, A.F., Bader, M., Suchkova, I.O., Baranova, T.V., Sorokin, A.V., Gaitskhoki, V.S. and Patkin, E.L.
Tsitologiia 41
: 693-697.
1 January 1999
Transcriptional regulation of the rat renin gene by regulatory elements in intron I.
Voigtlaender, T., Ganten, D. and Bader, M.
Hypertension 33
: 303-311.
1 January 1999
Gender-specific alterations of heart rate and blood pressure variability in Mas-deficient mice.
Walter, T., Wessel, N., Kang, N., Sander, A., Malberg, H., Bader, M. and Voss, A.
Journal of Clinical Basic Cardiology 2
(2): 281-282.
1999
Heat stress-induced B1 receptor synthesis in the rat: an ex vivo study.
Lagneux, C., Innocenti-Francillard, P., Godin-Ribuot, D., Bader, M. and Ribuot, C.
British Journal of Pharmacology 125
: 812-816.
1 October 1998
Molecular biology of the kallikrein-kinin system: from structure to function.
Pesquero, J.B. and Bader, M.
Brazilian Journal of Medical and Biological Research 31
: 1197-1203.
1 September 1998
Transgenic animal models for the functional analysis of vasoactive peptides.
Bader, M.
Brazilian Journal of Medical and Biological Research 31
: 1171-1183.
1 September 1998
Cloning and chromosomal localisation of the murine epidermal-type fatty acid binding protein gene (Fabpe).
Bleck, B., Hohoff, C., Binas, B., Ruestow, B., Dixkens, C., Hameister, H., Boerchers, T. and Spener, F.
Gene 215
: 123-130.
17 July 1998
A simple technique to isolate DNA and supernatant of genital Mycoplasma hominis and Ureaplasma urealyticum.
Walther, T., Retzlaff, C., Stepan, H. and Faber, R.
Journal of Perinatal Medicine 26
: 123-124.
1 January 1998
Alternative splicing of the mRNA coding for the human endothelial angiotensin-converting enzyme: a new mechanism for solubilization.
Sugimura, K., Tian, X.L., Hoffmann, S., Ganten, D. and Bader, M.
Biochemical and Biophysical Research Communications 247
: 466-472.
1 January 1998
C-type natriuretic peptide in maternal plasma in spontaneous labour, at elective cesarean section and during puerperium.
Stepan, H., Walther, T. and Faber, R.
Journal of Perinatal Medicine 26
: 396-399.
1 January 1998
Cortical and medullary hemodynamics in deoxycorticosterone acetate-salt hypertensive mice.
Gross, V., Lippoldt, A., Bohlender, J., Bader, M., Hansson, A. and Luft, F.C.
Journal of the American Society of Nephrology 9
: 346-354.
1 January 1998
Detection of C-type natriuretic peptide in normal pregnancy.
Stepan, H., Walther, T., Walther, D. and Faber, R.
Journal of Perinatal Medicine 26
: 56-58.
1 January 1998
Local renin-angiotensin system in the pineal gland.
Baltatu, O., Lippoldt, A., Hansson, A., Ganten, D. and Bader, M.
Molecular Brain Research 54
: 237-242.
1 January 1998
Sustained long-term potentiation and anxiety in mice lacking the Mas protooncogene.
Walther, T., Balschun, D., Voigt, J.P., Fink, H., Zuschratter, W., Birchmeier, C., Ganten, D. and Bader, M.
Journal of Biological Chemistry 273
: 11867-11873.
1 January 1998
Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex.
Hermans-Borgmeyer, I., Hampe, W., Schinke, B., Methner, A., Nykjaer, A., Suesens, U., Fenger, U., Herbarth, B. and Schaller, H.C.
Mechanisms of Development 70
(1-2): 65-76.
January 1998
Brain angiotensins in the cardiovascular regulation: usefulness of transgenic animals.
Bricca, G., Schinke, M., Boehm, M., Monti, J., Hof, H., Ganten, D. and Bader, M.
Fundamental & Clinical Pharmacology 11, Suppl.1
: 53s-57s.
1 January 1997
Effects of angiotensin II and IV on geniculate activity in nontransgenic and transgenic rats.
Albrecht, D., Broser, M., Krueger, H. and Bader, M.
European Journal of Pharmacology 332
: 53-63.
1 January 1997
High levels of human chymase expression in the pineal and pituitary glands.
Baltatu, O., Nishimura, H., Hoffmann, S., Stoltenburg, G., Haulica, I.D., Lippoldt, A., Ganten, D. and Urata, H.
Brain Research 752
: 269-278.
1 January 1997
Inhibition of brain renin-angiotensin-system by triple-helix-forming oligonucleotides is associated with modulation of blood pressure power spectrum in rats.
Monti, J., Voss, A., Schinke, M., Boehm, M., Hoff, H., Bader, M., Ganten, D. and Bricca, G.
Fundamental & Clinical Pharmacology 11 Suppl. 1
: S116.
1 January 1997
Nitric oxide synthase and renin angiotensin system gene expression in salt-sensitive and salt-resistant Sabra rats.
Lippoldt, A., Gross, V., Schneider, K., Hansson, A.C., Nadaud, S., Schneider, W., Bader, M., Yagil, S.A., Yagil, J. and Luft, F.C.
Hypertension 30
: 409-415.
1 January 1997
Prednicarbate versus conventional topical glucocorticoids: Pharmacodynamic characterization in vitro.
Lange, K., Gysler, A., Bader, M., Kleuser, B., Korting, H.C. and Schaefer-Korting, M.
Pharmacological Research 14, 12
: 1744-1749.
1 January 1997
Rat embryonic stem cells: a progress report.
Brenin, D.R., Look, J., Bader, M., Hübner, N., Levan, G. and Iannaccone, P.
Transplantation Proceedings 29
: 1761-1765.
1 January 1997
Renovascular hypertension with low-to-normal plasma renin: clinical and angiographic features.
Rossi, G.P., Pavan, E., Chiesura-Corona, M., Bader, M., Paganini, G., Cesari, M., De Toni, R., Feltrin, G.P., Ganten, D. and Pessina, A.C.
Clinical Science 93
: 435-443.
1 January 1997
Angiotensin I converting enzyme and chymase in cardiovascular tissues.
Nishimura, H., Hoffmann, S., Baltatu, O., Sugimura, K., Ganten, D. and Urata, H.
Kidney International 49,Suppl.55
: S18-S23.
1 January 1996
Angiotensinogen messenger RNA stabilization by angiotensin II.
Klett, C., Printz, M.P., Bader, M., Ganten, D. and Eggena, P.
Journal of Hypertension 14, Suppl.4
: S25-S36.
1 January 1996
Behaviour of the transgenic (mRen2)27 rat.
Wilson, W., Voigt, P., Bader, M., Marsden, C.A. and Fink, H.
Brain Research 729
: 1-9.
1 January 1996
Molecular cloning and functional characterization of a mouse bradykinin B1 receptor gene.
Pesquero, J.B., Pesquero, J.L., Oliveira, S.M., Roscher, A.A., Metzger, R., Ganten, D. and Bader, M.
Biochemical and Biophysical Research Communications 220
(1): 219-225.
1 January 1996
Permanent inhibition of angiotensinogen synthesis by antisense RNA expression.
Schinke, M., Boehm, M., Bricca, G., Ganten, D. and Bader, M.
Hypertension 27
: 508-513.
1 January 1996
Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade.
Boehm, M., Lippoldt, A., Wienen, W., Ganten, D. and Bader, M.
Molecular and Cellular Biochemistry 163-164
: 217-221.
1 January 1996
Transcriptional regulatory elements in the rat bradykinin B2 receptor gene.
Pesquero, J.B., Lindsey, C.J., Paiva, A.C.M., Ganten, D. and Bader, M.
Immunopharmacology 33
: 36-41.
1 January 1996
Transgenic rats: tools to study the function of the renin-angiotensin system. Proceedings of the symposium 'angiotensin AT1 receptors: from molecular physiology to therapeutics'.
Bader, M. and Ganten, D.
Clinical and Experimental Pharmacology and Physiology Suppl.3
: S81-S87.
1 January 1996
Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions.
Boehm, M., Lee, M.A., Kreutz, R., Kim, S., Schinke, M., Djavidani, B., Wagner, J., Kaling, M., Wienen, W., Bader, M. and Ganten, D.
Journal of Hypertension 13
: 891-899.
1 January 1995
Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27.
Djavidani, B., Sander, M., Kreutz, R., Zeh, K., Bader, M., Mellon, S.H., Vecsei, P., Peters, J. and Ganten, D.
Journal of Hypertension 13
(6): 637-645.
1 January 1995
Contribution of A 12 kDa protein to the angiotensin II-induced stabilization of angiotensinogen mRNA : interaction with the 3'untranslated mRNA.
Klett, C., Bader, M., Schwemmle, M., Ganten, D. and Hackenthal, E.
Journal of Molecular Endocrinology 14
: 209-226.
1 January 1995
Differential gene expression of renin and angiotensinogen in the TGR(mREN-2)27 transgenic rat.
Lee, M.A., Boehm, M., Kim, S., Bachmann, S., Bachmann, J., Bader, M. and Ganten, D.
Hypertension 25
: 570-580.
1 January 1995
Expression of the mouse and rat mas proto-oncogene in the brain and peripheral tissues.
Metzger, R., Bader, M., Ludwig, T., Berberich, C., Bunnemann, B. and Ganten, D.
FEBS Letters 357
: 27-32.
1 January 1995
Molecular structure of rat bradykinin B2 receptor gene.
Pesquero, J.B., Lindsey, C.J., Zeh, K., Paiva, A.C.M., Ganten, D. and Bader, M.
Nieren- und Hochdruckkrankheiten 24
: 602-604.
1 January 1995
Transcriptional silencer in intron I of the rat renin gene.
Voigtlaender, T., Ripperger, A., Ganten, D. and Bader, M.
Advances in Experimental Medicine and Biology 377
: 285-292.
1 January 1995
Gene expression, localization, and characterization of endothelin A and B receptors in the human adrenal cortex.
Rossi, G.P., Albertin, G., Belloni, A., Zanin, L., Biasolo, M.A., Prayer-Galetti, T., Bader, M., Nussdorfer, G.G., Palu, G. and Pessina, A.C.
Journal of Clinical Investigation 94
(3): 1226-1234.
September 1994
Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents.
Maltsev, V.A., Wobus, A.M., Rohwedel, J., Bader, M. and Hescheler, J.
Circulation Research 75
(2): 233-244.
1 August 1994
Characterization of the Han:SPRD rat model for hereditary polycystic kidney disease.
Schaefer, K., Gretz, N., Bader, M., Oberbaeumer, I., Eckardt, K.U., Kriz, W. and Bachmann, S.
Kidney International 46
: 134-152.
1 January 1994
Focal overexpression of collagen IV characterizes the initiation of epithelial changes in polycystic kidney disease.
Schaefer, K., Bader, M., Gretz, N., Oberbaeumer, I. and Bachmann, S.
Experimental Nephrology 2
: 190-195.
1 January 1994
Mechanism by which angiotensin II stabilizes messenger RNA for angiotensinogen.
Klett, C., Bader, M., Ganten, D. and Hackenthal, E.
Hypertension 23
: I120-I125.
1 January 1994
Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing.
Pesquero, J.B., Lindsey, C.J., Zeh, K., Paiva, A.C.M., Ganten, D. and Bader, M.
Journal of Biological Chemistry 43
: 26920-26925.
1 January 1994
The role of the renin-angiotensin system in cardiovascular disease.
Bader, M., Wagner, J., Lee, M.A. and Ganten, D.
Hypertension Research 17
: 1-16.
1 January 1994
Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II and calcium.
Peters, J., Muenter, K., Bader, M., Hackenthal, E., Mullins, J.J. and Ganten, D.
Journal of Clinical Investigation 91
(3): 742-747.
March 1993
Expression of the mouse ren-2 gene in the small intestine is regulated by food intake.
Zhao, Y., Peters, J., Ganten, D. and Bader, M.
Pfluegers Archiv European Journal of Physiology 424
: 199-202.
1 January 1993
Extra-hepatic transcription of plasma prekallikrein gene in human and rat tissues.
Ciechanowicz, A., Bader, M., Wagner, J. and Ganten, D.
Biochemical and Biophysical Research Communications 197
: 1370-1376.
1 January 1993
Investigating the genetics of hypertension.
Bader, M., Paul, M. and Ganten, D.
ACE Report 99
: 6-10.
1 January 1993
Ontogenetic regulation of the mouse Ren-2d renin gene in transgenic hypertensive rats TGR(mREN2)27.
Zhao, Y., Bader, M., Kreutz, R., Fernandez-Alfonso, M.S., Zimmermann, F., Ganten, U., Metzger, R., Ganten, D., Mullins, J.J. and Peters, J.
American Journal of Physiology 265
: E699-E707.
1 January 1993
Regulation adrenaler Aldosteronsekretion und adrenalen Renins in TGR(mREN2)27.
Peters, J., Djavidani, B., Sander, M., Bader, M. and Ganten, D.
Nieren- und Hochdruckkrankheiten 22
: 364-368.
1 January 1993
The renin-angiotensin system in the brain. Localization and functional significance.
Paul, M., Bader, M., Steckelings, U.M., Voigtlaender, T. and Ganten, D.
Arzneimittelforschung 43
: 207-213.
1 January 1993
Update on the renin-angiotensin system. Recent advances in molecular biology.
Wagner, J., Fernandez-Alfonso, M.S., Bachmann, J., Bader, M., Paul, M. and Ganten, D.
Nutrition, Metabolism, and Cardiovascular Diseases 3
: 197-203.
1 January 1993
Expression of nitric oxide synthase in kidney macula densa cells.
Mundel, P., Bachmann, S., Bader, M., Fischer, A., Kummer, W., Mayer, B. and Kriz, W.
Kidney International 42
(4): 1017-1019.
1 October 1992
The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.
Sander, M., Bader, M., Djavidani, B., Masergluth, C., Vecsei, P., Mullins, J.J., Ganten, D. and Peters, J.
Endocrinology 131
(2): 807-814.
1 August 1992
Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes.
Ganten, D., Wagner, J., Zeh, K., Bader, M., Michel, J.B., Paul, M., Zimmermann, F., Ruf, P., Hilgenfeldt, U., Ganten, U., Kaling, M., Bachmann, S., Fukamizu, A., Mullins, J.J. and Murakami, K.
Proceedings of the National Academy of Sciences of the United States of America 89
: 7806-7810.
August 1992
Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats.
Bader, M., Zhao, Y., Sander, M., Lee, M.A., Bachmann, J., Boehm, M., Djavidani, B., Peters, J., Mullins, J.J. and Ganten, D.
Hypertension 19
(6 Pt 2): 681-686.
1 June 1992
Expression des Ren-2-Gens der Maus im Duenndarm von DBA/2-Maeusen und transgenen Ratten.
Zhao, Y., Peters, J., Matsuda, T., Mullins, J.J., Bader, M. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21
: 642-643.
1 January 1992
Gesteigerte Aldosteronbiosynthese in TGR(mREN2)27: Funktionelle Bedeutung eines lokalen intraadrenalen Renin-Angiotensin-Systems.
Peters, J., Djavidani, B., Muenter, K., Bader, M., Sander, M., Mullins, J.J. and Ganten, D.
Nieren- und Hochdruckkrankheiten 21
: 545-546.
1 January 1992
Preparation and analysis of transgenic rats expressing the mouse Ren-2 gene.
Lee, M.A., Zhao, Y., Peters, J., Ganten, D., Zimmermann, F., Ganten, U., Bachmann, S., Bader, M. and Mullins, J.J.
Journal of Vascular Medicine and Biology 3
: 50-54.
1 January 1991
Transgenic rats: new animal models in hypertension research. Invited lecture.
Ganten, D., Lindpaintner, K., Ganten, U., Peters, J., Zimmermann, F., Bader, M. and Mullins, J.J.
Hypertension 17
: 843-855.
1 January 1991
Book Section
Transgenic animal models for the functional analysis of ACE2.
Alenina, N. and Bader, M.
In:
Angiotensin : from the kidney to coronavirus.
Molecular Mediators in Health and Disease: How Cells Communicate
.
Elsevier / Academic Press, London, 491-503.
ISBN 978-0-323-99618-1
2023
Bradykinin receptors.
Maghsodi, S., Qadri, F. and Bader, M.
In:
Reference Module in Life Sciences.
Encyclopedia of Biological Chemistry III (Third Edition), 6
.
Elsevier, 142-160.
ISBN 978-0-12-822040-5
2021
Renin-angiotensin-aldosterone system.
Bader, M.
In:
Encyclopedia of Molecular Pharmacology : Third Edition.
Springer, Cham, 1353-1358.
ISBN 978-3-030-57400-0
2021
The serotonin-free brain: behavioral consequences of Tph2 deficiency in animal models.
Mosienko, V., Bader, M. and Alenina, N.
In:
Handbook of the Behavioral Neurobiology of Serotonin.
Handbook of Behavioral Neuroscience, 31
.
Elsevier, London et al., 601-607.
ISBN 978-0-444-64125-0
2020
Genetic models.
Alenina, N. and Bader, M.
In:
Angiotensin-(1-7) : a comprehensive review.
Springer, Cham, 35-51.
ISBN 978-3-030-22695-4
2019
Nikolai V. Timoféeff-Ressovsky in Berlin-Buch (1925–1945).
Rajewsky, M., Lafuente, D. and Bader, M.
In:
Genetics, Evolution and Radiation.
Springer, 13-28.
ISBN 978-3-319-48837-0
2016
Angiotensin-(1-7) and Mas: a brief history.
Alenina, N. and dos Santos, R.A.
In:
The Protective Arm of the Renin Angiotensin System (RAS).
Elsevier, Amsterdam, NL, 155-159.
ISBN 9780128013649
2015
Animal models with a genetic alteration of the ACE2/Ang-(1-7)/Mas axis.
Rabelo, L.A., Nunes-Souza, V. and Bader, M.
In:
The Protective Arm of the Renin Angiotensin System (RAS).
Elsevier, Amsterdam, NL, 161-168.
ISBN 9780128013649
2015
Kallikrein-kinin system in inflammation.
Duchene, J. and Ahluwalia, A.
In:
Kinins.
de Gruyter, 261-272.
ISBN 978-3-11-025234-7
November 2011
Kinins: History and outlook.
Bader, M.
In:
Kinins.
de Gruyter, 1-6.
ISBN 978-3-11-025234-7
November 2011
Kinins.
Macedo de Oliveira, S., de Picoli Souza, K., Bader, M. and Pesquero, J.B.
In:
Cardiovascular Hormone Systems.
Wiley-Blackwell, 101-123.
ISBN 9783527319206
10 September 2008
Serotonin.
Bader, M.
In:
Cardiovascular Hormone Systems.
Wiley-Blackwell, 209-231.
ISBN 9783527319206
10 September 2008
Angiotensin.
Baltatu, O. and Bader, M.
In:
Encyclopedia of Stress.
UNSPECIFIED, 182-186.
ISBN 978-0-12-373947-6
2007
Renin.
Bader, M.
In:
xPharm: The Comprehensive Pharmacology Reference.
UNSPECIFIED, 1-10.
ISBN 978-0-08-055232-3
2007
Induction and analysis of cardiac hypertrophy in transgenic animal models.
Barbosa, M.E., Alenina, N. and Bader, M.
In:
Molecular cardiology: Methods and protocols.
Methods in Molecular Medicine ; 112
.
Humana Press, Totowa, NJ, 339-352.
ISBN 1-58829-363-7
1 January 2005
Mouse knockout models of hypertension.
Bader, M.
In:
Hypertension: Methods and Protocols.
Methods in Molecular Medicine ; 108
.
Humana Press, Totowa (NJ), 17-32.
ISBN 1543-1894
25 October 2004
Production of transgenic models in hypertension.
Popova, E., Bader, M. and Krivokharchenko, A.
In:
Hypertension: Methods and Protocols.
Methods in Molecular Medicine ; 108
.
Humana Press, Totowa (NJ), 33-50.
ISBN 1543-1894
25 October 2004
Transgenics of the RAS.
Bader, M. and Ganten, D.
In:
Angiotensin, Vol. 1.
Handbook of Experimental Pharmacology ; 163, 1
.
Springer, Berlin [u.a.], 229-249.
ISBN 3-540-40640-9
1 January 2004
Role of local renin angiotensin systems in cardiac damage.
Bader, M.
In:
Renin Angiotensin System and the Heart.
John Wiley & Sons, 47-62.
ISBN 9780470862926
2004
Grundlagen der molekularen Zellbiologie.
Bader, M. and Behrens, J.
In:
Grundlagen der Molekularen Medizin.
Molekulare Medizin
.
Springer, Berlin [u.a.], 3-53.
ISBN 3-540-43207-8
1 January 2003
Functional testing of components of the brain renin-angiotensin system in transgenic animals.
Baltatu, O., Bader, M. and Ganten, D.
In:
Renin-angiotensin : Proceedings from a Symposium held at the Wenner-Gren Research Institute, Stockholm, in September 1997, honouring Robert Tigerstedt and his Discovery of the Renin-angiotensin System.
Wenner-Gren International Series ; 74
.
Portland, London, 105-114.
ISBN 1-85578-128-X
1 January 1998
Grundlagen der molekularen Zellbiologie.
Bader, M.
In:
Molekular- und Zellbiologische Grundlagen.
Handbuch der Molekularen Medizin ; 1
.
Springer, Berlin [u.a.], 3-50.
1 January 1997
Basic methods of molecular biology in cardiovascular research.
Paul, M., Bader, M., Wagner, J. and Ganten, D.
In:
Molecular Cell Biology of Cardiovascular Diseases.
Mosby, Madrid [u.a.], 41-48.
1 January 1994
Molecular biology and biochemistry of the renin-angiotensin system.
Bader, M., Paul, M., Fernandez-Alfonso, M.S., Kaling, M. and Ganten, D.
In:
Textbook of Hypertension.
Blackwell, Oxford, 214-232.
1 January 1994
Transgenic animal models for hypertension.
Paul, M., Wagner, J., Bader, M. and Ganten, D.
In:
Textbook of Hypertension.
Blackwell, Oxford, 469-476.
1 January 1994
Transgenic rats expressing components of the renin-angiotensin system : focus on cardiovascular regulation.
Paul, M., Wagner, J., Kreutz, R., Fernandez-Alfonso, M.S., Liu, Y., Bader, M. and Ganten, D.
In:
The Cardiac Renin-Angiotensin System.
Futura Publ. Comp., Armonk, [s.p.].
1 January 1994
Renin gene expression and hypertension in transgenic animals.
Bader, M., Lee, M.A., Zhao, Y., Boehm, M., Bachmann, J., Sander, M., Djavidani, B., Bachmann, S., Zimmermann, F., Wilbertz, J., Zeh, K., Wagner, J., Peters, J. and Ganten, D.
In:
Cellular and Molecular Biology of the Renin-Angiotensin System.
CRC Press, Boca Raton, 60-93.
1 January 1993
Primary hypertension and the renin angiotensin system - from the laboratory experiment to clinical relevance.
Bader, M., Kreutz, R., Wagner, J., Zeh, K., Boehm, M., Paul, M. and Ganten, D.
In:
Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats, (Colloque Inserm ; 218).
John Libbey Eurotext, Paris, 359-371.
1 January 1992
The role of adrenal renin in steroid metabolism and development of hypertension in transgenic rats TGR(Messenger REN2).
Peters, J., Sander, M., Munter, K., Lee, M.A., Djavidani, B., Bader, M., Maser-Gluth, C., Vecsei, P., Ganten, D. and Mullins, J.J.
In:
Genetic Hypertension : 7th International Symposium on Spontaneously Hypertensive Rats (Colloque Inserm ; 218).
John Libbey Eurotext, Paris, 345-347.
1 January 1992
Angiotensin in hypertension: new aspects.
Ganten, D., Paul, M., Bader, M. and Mullins, J.J.
In:
Peptide Regulation of Cardiovascular Function.
Academic Press, Tokyo, 167-190.
1 January 1991
Tissue distribution of ren-2 expression in transgenic rats.
Peters, J., Bader, M., Ganten, D. and Mullins, J.J.
In:
Genetic Approaches to Coronary Heart Disease and Hypertension.
Springer, Berlin [u.a.], 74-80.
1 January 1991
Book
Kinins.
Bader, M.
de Gruyter.
ISBN 978-3-11-025234-7
November 2011
Cardiovascular hormone systems.
Bader, M., ed.
Wiley-Blackwell, 1-433.
ISBN 9783527319206
10 September 2008
Patent
Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same.
Max-Delbrück-Centrum für Molekulare Medizin.
201615552556.
22 February 2018
Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same.
Max-Delbrück-Centrum für Molekulare Medizin.
WO/2016/135199.
1 September 2016
Neuronal exprimierte Tryptophanhydroxylase und ihre Verwendung [Neuronally expressed tryptophane hydroxylase and its use].
Walther, D. and Bader, M.
DE10232151A1 ; WO0407704.
5 February 2004
Mittel zur Behandlung des Schlaganfalls.
Mies, G., Bader, M. and Pesquero, J.B.
DE10115668A1.
10 October 2002
Verwendung von Tryptophan-Derivaten zur spezifischen zytostatischen Behandlung von Serotonin-produzierenden Tumoren [Use of tryptophan derivatives for the specific cytostatic treatment of serotonin-producing tumors].
Walther, D. and Bader, M.
DE10112882A1 ; EP1368027 ; WO0274309.
19 September 2002
Verwendung von aus embryonalen Stammzellen hergeleiteten Zellen zur Erhoehung der Transplantationstoleranz und zur Wiederherstellung zerstoerten Gewebes [Use of cells derived from embryonic stem cells for increasing transplantation tolerance and for repairing damaged tissue].
Bader, M., Binas, B., Chai, G., Faendrich, F., Ganten, D. and Lin, X.
DE10061334A1 ; EP1341915 ; WO0246401.
13 June 2002
Mittel zur Beeinflussung der Angiogenese [Agent for influencing angiogenesis].
Bader, M., Pesquero, J.B., Madeddu, P. and Emanueli, C.
DE10141749A1 ; WO0217958.
14 March 2002
Verfahren zur Diagnostik von neuronalen Erkrankungen sowie zur Behandlung der defizienten primaeren Haemostase [Method for diagnosing neuronal diseases and for treating primary hemostasis deficiency].
Walther, D. and Bader, M.
DE10043124A1 ; EP1317265 ; WO0217891 ; US7,049,336.
14 March 2002
Review
Alternative renin-angiotensin system.
Bader, M., Muscha Steckelings, U., Alenina, N., Santos, R.A.S. and Ferrario, C.M.
Hypertension 81
(5): 964-976.
May 2024
The contribution of the AT1 receptor to erythropoiesis.
Rodrigues, A.F. and Bader, M.
Biochemical Pharmacology 217
: 115805.
November 2023
Crosstalk between the renin-angiotensin, complement and kallikrein-kinin systems in inflammation.
Bekassy, Z., Lopatko Fagerström, I., Bader, M. and Karpman, D.
Nature Reviews Immunology 22
(7): 411-428.
July 2022
Oxidative RNA damage in the pathogenesis and treatment of type 2 diabetes.
Chen, X., Yu, H., Li, Z., Ye, W., Liu, Z., Gao, J., Wang, Y., Li, X., Zhang, L., Alenina, N., Bader, M., Ding, H., Li, P. and Aung, L.H.H.
Frontiers in Physiology 13
: 725919.
28 March 2022
The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons.
Borroto-Escuela, D.O., Ferraro, L., Beggiato, S., Narváez, M., Fores-Pons, R., Alvarez-Contino, J.E., Wydra, K., Frankowska, M., Bader, M., Filip, M. and Fuxe, K.
Pharmacological Reports 73
(4): 1096-1108.
August 2021
Neurobiology of glycine transporters: from molecules to behavior.
Marques, B.L., Oliveira-Lima, O.C., Carvalho, G.A., de Almeida Chiarelli, R., Ribeiro, R.I., Parreira, R.C., da Madeira Freitas, E.M., Resende, R.R., Klempin, F., Ulrich, H., Gomez, R.S. and Pinto, M.C.X.
Neuroscience and Biobehavioral Reviews 118
: 97-110.
November 2020
Bradykinin B2 receptor signaling increases glucose uptake and oxidation: evidence and open questions.
Gregnani, M.F., Hungaro, T.G., Martins-Silva, L., Bader, M. and Araujo, R.C.
Frontiers in Pharmacology 11
: 1162.
4 August 2020
The dual role of serotonin in colorectal cancer.
Kannen, V., Bader, M., Sakita, J.Y., Uyemura, S.A. and Squire, J.A.
Trends in Endocrinology and Metabolism 31
(8): 611-625.
August 2020
Inhibition of serotonin synthesis: a novel therapeutic paradigm.
Bader, M.
Pharmacology & Therapeutics 205
: 107423.
January 2020
Oxidative stress in rheumatoid arthritis: what the future might hold regarding novel biomarkers and add-on therapies.
da Fonseca, L.J.S., Nunes-Souza, V., Goulart, M.O.F. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2019
(Special issue): 7536805.
16 December 2019
Serotonylation: serotonin signaling and epigenetics.
Bader, M.
Frontiers in Molecular Neuroscience 12
: 288.
21 November 2019
The renin-angiotensin system: going beyond the classical paradigms.
Santos, R.A.S., Oudit, G.Y., Verano-Braga, T., Canta, G., Steckelings, U.M. and Bader, M.
American Journal of Physiology Heart and Circulatory Physiology 316
(5): H958-H970.
May 2019
The Meaning of Mas.
Bader, M., Alenina, N., Young, D., Santos, R.A.S. and Touyz, R.M.
Hypertension 72
(5): 1072-1075.
November 2018
Peripheral serotonin synthesis as a new drug target.
Matthes, S. and Bader, M.
Trends in Pharmacological Sciences 39
(6): 560-572.
June 2018
Kinin B1 receptors as a therapeutic target for inflammation.
Qadri, F. and Bader, M.
Expert Opinion on Therapeutic Targets 22
(1): 31-44.
January 2018
The ACE2/angiotensin-(1-7)/MAS axis of the renin-angiotensin system: focus on angiotensin-(1-7).
Santos, R.A.S., Sampaio, W.O., Alzamora, A.C., Motta-Santos, D., Alenina, N., Bader, M. and Campagnole-Santos, M.J.
Physiological Reviews 98
(1): 505-553.
January 2018
Renin-angiotensin system in diabetes.
Rein, J. and Bader, M.
Protein and Peptide Letters 24
(9): 833-840.
17 November 2017
Physical exercise on inflammatory markers in type 2 diabetes patients: a systematic review of randomized controlled trials.
Melo, L.C., Dativo-Medeiros, J., Menezes-Silva, C.E., Barbosa, F.T., de Sousa-Rodrigues, C.. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2017
(2017): 8523728.
19 March 2017
Beyond gene inactivation: evolution of tools for analysis of serotonergic circuitry.
Hainer, C., Mosienko, V., Koutsikou, S., Crook, J.J., Gloss, B., Kasparov, S., Lumb, B.M. and Alenina, N.
ACS Chemical Neuroscience 6
(7): 1116-1129.
15 July 2015
Angiotensin type 2 receptor (AT2R) and receptor Mas: a complex liaison.
Villela, D., Leonhardt, J., Patel, N., Joseph, J., Kirsch, S., Hallberg, A., Unger, T., Bader, M., Santos, R.A., Sumners, C. and Steckelings, U.M.
Clinical Science 128
(4): 227-234.
1 February 2015
Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis.
Mosienko, V., Beis, D., Pasqualetti, M., Waider, J., Matthes, S., Qadri, F., Bader, M. and Alenina, N.
Behavioural Brain Research 277
(SI): 78-88.
15 January 2015
The role of serotonin in adult hippocampal neurogenesis.
Alenina, N. and Klempin, F.
Behavioural Brain Research 277
: 49-57.
15 January 2015
Arginase as a Critical Prooxidant Mediator in the Binomial Endothelial Dysfunction-Atherosclerosis.
Rabelo, L.A., Ferreira, F.O., Nunes-Souza, V., da Fonseca, L.J.S. and Goulart, M.O.F.
Oxidative Medicine and Cellular Longevity 2015
: 924860.
2015
Mas and its related G protein-coupled receptors, Mrgprs.
Bader, M., Alenina, N., Andrade-Navarro, M.A. and Santos, R.A.
Pharmacological Reviews 66
(4): 1080-1105.
October 2014
(Pro)renin receptor and V-ATPase: from Drosophila to humans.
Rousselle, A., Sihn, G., Rotteveel, M. and Bader, M.
Clinical Science 126
(8): 529-536.
1 April 2014
Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin angiotensin system.
Santos, R.A.S., Ferreira, A.J., Verano-Braga, T. and Bader, M.
Journal of Endocrinology 216
(2): R1-R17.
18 January 2013
ACE2, angiotensin-(1-7), and Mas: the other side of the coin.
Bader, M.
Pfluegers Archiv European Journal of Physiology 465
(1): 79-85.
January 2013
The Angiotensin-melatonin axis.
Campos, L.A., Cipolla-Neto, J., Amaral, F.G., Michelini, L.C., Bader, M. and Baltatu, O.C.
International Journal of Hypertension 2013
: 521783.
2013
Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D., Luft, F.C., Bader, M., Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90
(5): 495-508.
May 2012
Therapeutic targeting of the angiotensin-converting enzyme 2/Angiotensin-(1-7)/Mas cascade in the renin-angiotensin system: a patent review.
Ferreira, A.J., Bader, M. and Santos, R.A.S.
Expert Opinion on Therapeutic Patents 22
(5): 567-574.
May 2012
Brain renin-angiotensin system in hypertension, cardiac hypertrophy, and heart failure.
Campos, L.A., Bader, M. and Baltatu, O.C.
Frontiers in Physiology 2
: 115.
3 January 2012
Emerging drugs which target the renin-angiotensin-aldosterone system.
Steckelings, U.M., Paulis, L., Unger, T. and Bader, M.
Expert Opinion on Emerging Drugs 16
(4): 619-630.
December 2011
New topics in bradykinin research.
Maurer, M., Bader, M., Bas, M., Bossi, F., Cicardi, M., Cugno, M., Howarth, P., Kaplan, A., Kojda, G., Leeb-Lundberg, F., Loetvall, J. and Magerl, M.
Allergy 66
(11): 1397-1406.
November 2011
Local renin angiotensin system and the brain-A continuous quest for knowledge.
Baltatu, O.C., Campos, L.A. and Bader, M.
Peptides 32
(5): 1083-1086.
May 2011
ACE2-angiotensin-(1-7)-Mas axis and oxidative stress in cardiovascular disease.
Rabelo, L.A., Alenina, N. and Bader, M.
Hypertension Research 34
(2): 154-160.
February 2011
SDF-1alpha as a therapeutic stem cell homing factor in myocardial infarction.
Ghadge, S.K., Muehlstedt, S., Oezcelik, C. and Bader, M.
Pharmacology & Therapeutics 129
(1): 97-108.
January 2011
Leptin regulates ACE activity in mice.
Hilzendeger, A.M., Morais, R.L., Todiras, M., Plehm, R., da Costa Goncalves, A., Qadri, F., Araujo, R.C., Gross, V., Nakaie, C.R., Casarini, D.E., Carmona, A.K., Bader, M. and Pesquero, J.B.
Journal of Molecular Medicine 88
(9): 899-907.
September 2010
Physiology of the (pro)renin receptor: Wnt of change?
Sihn, G., Rousselle, A., Vilianovitch, L., Burckle, C. and Bader, M.
Kidney International 78
(3): 246-256.
August 2010
Behavioral evidence for the significance of serotoninergic (5-HT) receptors in cocaine addiction.
Filip, M., Alenina, N., Bader, M. and Przegalinski, E.
Addiction Biology 15
(3): 227-249.
July 2010
Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy.
Bader, M.
Annual Review of Pharmacology and Toxicology 50
: 439-65.
2010
Tryptophan hydroxylase as novel target for the treatment of depressive disorders.
Matthes, S., Mosienko, V., Bashammakh, S., Alenina, N. and Bader, M.
Pharmacology 85
(2): 95-109.
2010
Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system.
Filip, M. and Bader, M.
Pharmacological Reports 61
(5): 761-777.
September 2009
Update on tissue renin-angiotensin systems.
Bader, M. and Ganten, D.
Journal of Molecular Medicine 86
(6): 615-621.
June 2008
Angiotensin-converting enzyme inhibition after experimental myocardial infarct: Role of the kinin B1 and B2 receptors.
Duka, A., Kintsurashvili, E., Duka, I., Ona, D., Hopkins, T.A., Bader, M., Gavras, I. and Gavras, H.
Hypertension 51
(5): 1352-1357.
May 2008
Genetically altered animal models for Mas and Angiotensin-(1-7).
Alenina, N., Xu, P., Rentzsch, B., Patkin, E.L. and Bader, M.
Experimental Physiology 93
(5): 528-537.
May 2008
Genetically altered animals in the study of the metabolic functions of peptide hormone systems.
Alves-da-Silva Mori, M., Bader, M. and Pesquero, J.B.
Current Opinion in Nephrology and Hypertension 17
(1): 11-17.
January 2008
Natriuretic peptide receptor B signaling in the cardiovascular system: protection from cardiac hypertrophy.
Pagel-Langenickel, I., Buttgereit, J., Bader, M. and Langenickel, T.H.
Journal of Molecular Medicine 85
(8): 797-810.
August 2007
Embryonic stem cells share immune-privileged features relevant for tolerance induction.
Faendrich, F., Dresske, B., Bader, M. and Schulze, M.
Journal of Molecular Medicine 80
(6): 343-350.
1 January 2002
Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research.
Bader, M., Peters, J., Baltatu, O., Mueller, D.N., Luft, F.C. and Ganten, D.
Journal of Molecular Medicine 79
(2): 76-102.
1 January 2001
Transgenic animals in cardiovascular disease research.
Bader, M., Bohnemeier, H., Zollmann, F.S., Lockley-Jones, O.E. and Ganten, D.
Experimental Physiology 85
(6): 713-731.
1 November 2000
A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland.
Gordon, K.E., Binas, B., Chapman, R.S., Kurian, K.M., Clarkson, R.W.E., Clark, A.J., Lane, E.B. and Watson, C.J.
Breast Cancer Research 2
(3): 222-235.
1 January 2000
Regulation of renin: new evidence from cultured cells and genetically modified mice.
Bader, M. and Ganten, D.
Journal of Molecular Medicine 78
(3): 130-139.
1 January 2000
Physiological characterization of the hypertensive transgenic rat TGR(mREN2)27.
Lee, M.A., Boehm, M., Paul, M., Bader, M., Ganten, U. and Ganten, D.
American Journal of Physiology Endocrinology and Metabolism 270
: E919-E929.
1 January 1996
Progress in molecular medicine. From experimental genetics to the treatment of hypertensive patients.
Ganten, D., Kreutz, R., Bader, M. and Wagner, J.
Chinese Medical Journal 106
: 375-384.
1 January 1993
Basic methodology in the molecular characterization of genes.
Bader, M., Kaling, M., Metzger, R., Peters, J., Wagner, J. and Ganten, D.
Journal of Hypertension 10
: 9-16.
1 January 1992
Letter
Renin is essential for angiotensin II formation in the brain.
Rodrigues, A.F., Domenig, O., Garrelds, I.M., Danser, J.A.H., Alenina, N., Poglitsch, M. and Bader, M.
Journal of the American Heart Association 13
(22): e034209.
19 November 2024
Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A., Walter, S., Markó, L., McMurray, B.J., Sunaga-Franze, D.Y., Xu, M., Zühlke, K., Russwurm, M., Bartolomaeus, T.U.P., Langanki, R., Qadri, F., Heuser, A., Patzak, A., Forslund, S.K., Bähring, S., Borodina, T., Persson, P.B., Maass, P.G., Bader, M. and Klussmann, E.
Kidney International 104
(2): 388-393.
August 2023
Why angiotensin II is a poor choice for circulatory support of ventilated COVID-19 patients compared to vasopressin.
Speth, R.C. and Bader, M.
Medical Research Archives 10
(9): 3079.
September 2022
Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity.
Batlle, D., Monteil, V., Garreta, E., Hassler, L., Wysocki, J., Chandar, V., Schwartz, R.E., Mirazimi, A., Montserrat, N., Bader, M. and Penninger, J.M.
Cell 185
(11): 1837-1839.
26 May 2022
Laying out the evidence for the persistence of neurogenesis in the adult human hippocampus.
Kronenberg, G. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 270
(4): 497-498.
June 2020
The (pro)renin receptor: what's in a name?
Simons, M., Bader, M. and Müller, D.N.
Nature Reviews Nephrology 16
(5): 304.
May 2020
Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.
Cui, Y., Niziolek, P.J., MacDonald, B.T., Alenina, N., Matthes, S., Jacobsen, C.M., Conlon, R.A., Brommage, R., Powell, D.R., He, X., Bader, M., Williams, B.O., Warman, M.L. and Robling, A.G.
Nature Medicine 20
(11): 1229-1230.
6 November 2014
Role of bradykinin and catecholamines in cerebral infarction and brain edema - Response.
Kleinschnitz, C., Austinat, M., Stoll, G., Bader, M. and Renne, T.
Stroke 40
(4): e104.
April 2009
Variations in DSG2: V56M, V158G and V920G are not pathogenic for arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Posch, M.G., Posch, M.J., Perrot, A., Dietz, R. and Oezcelik, C.
Nature Clinical Practice Cardiovascular Medicine 5
(12): E1.
December 2008
Deficiency of bradykinin receptor B2 is not detrimental in experimental stroke.
Kleinschnitz, C., Austinat, M., Bader, M., Renne, T. and Stoll, G.
Hypertension 51
(5): e41.
May 2008
We need a detailed phenome in the phenomenon of genetics and congenital heart disease.
Posch, M.G., Berger, F., Perrot, A. and Oezcelik, C.
Journal of Medical Genetics 45
(5): 320.
May 2008
Normal brain development in importin-alpha5 deficient-mice.
Shmidt, T., Hampich, F., Ridders, M., Schultrich, S., Hans, V.H., Tenner, K., Vilianovich, L., Qadri, F., Alenina, N., Hartmann, E., Koehler, M. and Bader, M.
Nature Cell Biology 9
(12): 1337-1338.
December 2007
Support for the involvement of TPH2 gene in affective disorders.
Harvey, M., Shink, E., Tremblay, M., Gagne, B., Raymond, C., Labbe, M., Walther, D.J., Bader, M. and Barden, N.
Molecular Psychiatry 9
(11): 980-981.
20 July 2004
Editorial
Tail-cuff versus radiotelemetry to measure blood pressure in mice and rats.
Harrison, D.G., Bader, M., Lerman, L.O., Fink, G., Karumanchi, S.A., Reckelhoff, J.F., Sequeira-Lopez, M.L.S. and Touyz, R.M.
Hypertension 81
(1): 3-5.
January 2024
Kinins: Locally formed peptides during inflammation with potential use in tissue regeneration.
Martins, L., Bader, M. and Pesquero, J.B.
Inflammation Research 72
(10-11): 1957-1963.
November 2023
Cardiovascular peptide hormones - special edition.
Braga, T.V., Mervaala, E., Santos, R. and Bader, M.
Peptides 167
: 171062.
September 2023
Editorial: Sexual dimorphism in biomedical research and its therapeutic implications.
Kroon, J., Mahmoodzadeh, S. and Helsen, C.
Frontiers in Endocrinology 13
: 1009712.
19 August 2022
The continued need for animals to advance brain research.
Homberg, J.R., Adan, R.A.H., Alenina, N., Asiminas, A., Bader, M., Beckers, T., Begg, D.P., Blokland, A., Burger, M.E., van Dijk, G., Eisel, U.L.M., Elgersma, Y., Englitz, B., Fernandez-Ruiz, A., Fitzsimons, C.P., van Dam, A.M., Gass, P., Grandjean, J., Havekes, R., Henckens, M.J.A.G., Herden, C., Hut, R.A., Jarrett, W., Jeffrey, K., Jezova, D., Kalsbeek, A., Kamermans, M., Kas, M.J., Kasri, N.N., Kiliaan, A.J., Kolk, S.M., Korosi, A., Korte, S.M., Kozicz, T., Kushner, S.A., Leech, K., Lesch, K.P., Lesscher, H., Lucassen, P.J., Luthi, A., Ma, L., Mallien, A.S., Meerlo, P., Mejias, J.F., Meye, F.J., Mitchell, A.S., Mul, J.D., Olcese, U., González, A.O., Olivier, J.D.A., Pasqualetti, M., Pennartz, C.M.A., Popik, P., Prickaerts, J., de la Prida, L.M., Ribeiro, S., Roozendaal, B., Rossato, J.I., Salari, A.A., Schoemaker, R.G., Smit, A.B., Vanderschuren, L.J.M.J., Takeuchi, T., van der Veen, R., Smidt, M.P., Vyazovskiy, V.V., Wiesmann, M., Wierenga, C.J., Williams, B., Willuhn, I., Wöhr, M., Wolvekamp, M., van der Zee, E.A. and Genzel, L.
Neuron 109
(15): 2374-2379.
4 August 2021
ACE2, a multifunctional protein - from cardiovascular regulation to COVID-19.
Bader, M., Turner, A.J. and Alenina, N.
Clinical Science 134
(23): 3229-3232.
11 December 2020
Renin-angiotensin system in aortic aneurysm: still adding puzzle stones to an anything but complete picture.
Steckelings, U.M. and Bader, M.
Hypertension 72
(3): 579-581.
September 2018
Of mice and renin.
Bader, M.
Hypertension 70
(1): 35-37.
July 2017
Comeback of the rat in biomedical research.
Homberg, J.R., Woehr, M. and Alenina, N.
ACS Chemical Neuroscience 8
(5): 900-903.
17 May 2017
Redox homeostasis: unlocking the bottleneck in glia-to-neuron conversion.
Klempin, F., Gertz, K. and Kronenberg, G.
Stem Cell Investigation 4
: 7.
9 February 2017
Receptors, G proteins, and integration of calcium signalling.
Gudermann, T. and Bader, M.
Journal of Molecular Medicine 93
(9): 937-940.
September 2015
New therapeutic pathways in the RAS.
Bader, M., Santos, R.A., Unger, T. and Steckelings, U.M.
Journal of the Renin Angiotensin Aldosterone System 13
(4): 505-508.
December 2012
Bradykinin B2 receptor agonism: a novel therapeutic strategy for myocardial infarction?
Duchene, J. and Bader, M.
American Journal of Hypertension 23
(5): 459.
May 2010
Kallikrein-kinin system in neovascularization.
Bader, M.
Arteriosclerosis Thrombosis and Vascular Biology 29
(5): 617-619.
May 2009
Preface.
Bader, M.
Cardiovascular Hormone Systems
: xvii-xviii.
10 September 2008
An old couple: the renin-angiotensin system (RAS) and the Journal of Molecular Medicine (JMolMed).
Ganten, D., Bader, M. and Juergensen, J.S.
Journal of Molecular Medicine 86
(6): 609-610.
June 2008
KININ2007: Comeback for kinins.
Bader, M.
International Immunopharmacology 8
(2): 133-134.
February 2008
Prorenin and its ancient receptor.
Burckle, C. and Bader, M.
Hypertension 48
(4): 549-551.
October 2006
Matrix reloaded. The matrix metalloproteinase paradox.
Panek, A.N. and Bader, M.
Hypertension 47
(4): 640-641.
April 2006
Stem-cell research: the state of the art. Future regulations of embryonic-stem-cell research will be influenced more by economic interests and cultural history than by ethical concerns.
Pompe, S., Bader, M. and Tannert, C.
EMBO Reports 6
(4): 297-300.
1 January 2005
It's renin in the brain - Transgenic animals elucidate the brain renin-angiotensin system.
Bader, M. and Ganten, D.
Circulation Research 90
(1): 8-10.
1 January 2002
Preprint
Angiotensin-(1-5) is a potent endogenous angiotensin AT(2)-receptor agonist.
Souza-Silva, I.M., Peluso, A.A., Elsaafien, K., Nazarova, A.L., Assersen, K.B., Rodrigues-Ribeiro, L., Mohammed, M., Rodrigues, A.F., Nawrocki, A., Johansen, L.A., Jensen, P., de Kloet, A.D., Krause, E.G., DelBorgo, M., Maslov, I., Widdop, R.E., Santos, R.A., Bader, M., Larsen, M.R., Verano-Braga, T., Katritch, V., Sumners, C. and Steckelings, U.M.
bioRxiv
: 2024.04.05.588367v2.
18 April 2024
ATF4 orchestrates IL-1α-induced senescence in adult neural stem cells.
Neumann, S., Thelin, E.P., Sankavaram, S.R., Persson, S., Fonseca, L., Moruzzi, N., Iacobaeus, E., Bergsland, M., Popova, E., Bader, M., Svensson, M., Espinosa, A., Covacu, R. and Brundin, L.
bioRxiv
: 2024.03.17.585394.
17 March 2024
The lncRNA landscape of cardiac resident macrophages and identification of Schlafenlnc as a regulator of macrophage migratory function.
Dueck, A., Althaus, L., Heise, K., Esfandyari, D., Bayguen, S., Brandes, R.P., Gagneur, J., Jae, N., Knolle, P., Leisegang, M.S., Maegdefessel, L., Meitinger, T., Petzold, N., Ramanujam, D., Sager, H., Schulz, C., Theodorakis, E., Uzonyi, A., Weinberger, T., Bader, M., Schmidt-Supprian, M. and Engelhardt, S.
bioRxiv
: 2022.11.30.518576.
22 December 2022
Myogenic vasoconstriction requires canonical Gq/11 signaling of the angiotensin II type 1a receptor in the murine vasculature.
Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y.M., Schleifenbaum, J., Bader, M., Welsh, D.G., Huang, Y. and Gollasch, M.
bioRxiv
: 2020.09.09.289280.
11 September 2020
This list was generated on Sat Dec 21 16:53:56 2024 UTC.
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