Browse by Research Team

ACE Report

Investigating the genetics of hypertension.
Bader, M., Paul, M. and Ganten, D.
ACE Report 99 : 6-10. 1 January 1993

ACS Chemical Neuroscience

Targeted manipulation of brain serotonin: RNAi-mediated knockdown of tryptophan hydroxylase 2 in rats.
Matthes, S., Mosienko, V., Popova, E., Rivalan, M., Bader, M. and Alenina, N.
ACS Chemical Neuroscience 10 (7): 3207-3217. 17 July 2019

Comeback of the rat in biomedical research.
Homberg, J.R., Woehr, M. and Alenina, N.
ACS Chemical Neuroscience 8 (5): 900-903. 17 May 2017

Beyond gene inactivation: evolution of tools for analysis of serotonergic circuitry.
Hainer, C., Mosienko, V., Koutsikou, S., Crook, J.J., Gloss, B., Kasparov, S., Lumb, B.M. and Alenina, N.
ACS Chemical Neuroscience 6 (7): 1116-1129. 15 July 2015

Postnatal growth defects in mice with constitutive depletion of central serotonin.
Narboux-Neme, N., Angenard, G., Mosienko, V., Klempin, F., Pitychoutis, P.M., Deneris, E., Bader, M., Giros, B., Alenina, N. and Gaspar, P.
ACS Chemical Neuroscience 4 (1): 171-181. 16 January 2013

Acta Neuropathologica

Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G., Uhlemann, R., Richter, N., Klempin, F., Wegner, S., Staerck, L., Wolf, S., Uckert, W., Kettenmann, H., Endres, M. and Gertz, K.
Acta Neuropathologica 135 (4): 551. April 2018

Acta Neuropathologica Communications

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Yalcin, F., Haneke, H., Efe, I.E., Kuhrt, L.D., Motta, E., Nickl, B., Flüh, C., Synowitz, M., Dzaye, O., Bader, M. and Kettenmann, H.
Acta Neuropathologica Communications 12 (1): 50. 2 April 2024

Acta Neuropsychiatrica

Impact of genetic deletion of MrgD or Mas receptors in depressive-like behaviour in mice.
Becari, L., Fonseca, M.L.A., Gonçalves, S.C.A, Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Acta Neuropsychiatrica 35 (1): 27-34. February 2023

Acta Physiologica

Sex dependent differences in renal angiotensinogen as an early marker of diabetic nephropathy.
de Alencar Franco Costa, D., Todiras, M., Campos, L.A., Cipolla-Neto, J., Bader, M. and Baltatu, O.C.
Acta Physiologica 213 (3): 740-746. March 2015

Acta Physiologica Scandinavica

Genetic targeting of the brain renin-angiotensin system in transgenic rats: Impact on stress-induced renin release.
Baltatu, O., Campos, L.A. and Bader, M.
Acta Physiologica Scandinavica 181 (4): 579-584. 1 August 2004

Cytoplasmic fatty acid-binding protein facilitates fatty acid utilization by skeletal muscle.
Glatz, J.F.C., Schaap, F.G., Binas, B., Bonen, A., van der Vusse, G.J. and Luiken, J.J.F.P.
Acta Physiologica Scandinavica 178 (4): 367-371. August 2003

Addiction Biology

Behavioral evidence for the significance of serotoninergic (5-HT) receptors in cocaine addiction.
Filip, M., Alenina, N., Bader, M. and Przegalinski, E.
Addiction Biology 15 (3): 227-249. July 2010

Advances in Experimental Medicine and Biology

Transcriptional silencer in intron I of the rat renin gene.
Voigtlaender, T., Ripperger, A., Ganten, D. and Bader, M.
Advances in Experimental Medicine and Biology 377 : 285-292. 1 January 1995

Allergy

Endothelial B2-receptor overexpression as an alternative animal model for hereditary angioedema.
Lopes Veronez, C., Maghsodi, S., Todiras, M., Popova, E., Rodrigues, A.F., Qadri, F., Pesquero, J.B. and Bader, M.
Allergy 74 (10): 1998-2002. October 2019

New topics in bradykinin research.
Maurer, M., Bader, M., Bas, M., Bossi, F., Cicardi, M., Cugno, M., Howarth, P., Kaplan, A., Kojda, G., Leeb-Lundberg, F., Loetvall, J. and Magerl, M.
Allergy 66 (11): 1397-1406. November 2011

American Journal of Hypertension

Identification of a novel agonist-like autoantibody in preeclamptic patients.
Velloso, E.P., Pimentel, R.L., Braga, J.F., Cabral, A.C.V., Reis, Z.S.N., Bader, M., Santos, R.A.S. and Wallukat, G.
American Journal of Hypertension 29 (3): 405-412. March 2016

Bradykinin B2 receptor agonism: a novel therapeutic strategy for myocardial infarction?
Duchene, J. and Bader, M.
American Journal of Hypertension 23 (5): 459. May 2010

Baroreflex sensitivity, heart rate, and blood pressure variability in normal pregnancy.
Voss, A., Malberg, H., Schumann, A., Wessel, N., Walther, T., Stepan, H. and Faber, R.
American Journal of Hypertension 13 (11): 1218-1225. November 2000

American Journal of Physiology

Ontogenetic regulation of the mouse Ren-2d renin gene in transgenic hypertensive rats TGR(mREN2)27.
Zhao, Y., Bader, M., Kreutz, R., Fernandez-Alfonso, M.S., Zimmermann, F., Ganten, U., Metzger, R., Ganten, D., Mullins, J.J. and Peters, J.
American Journal of Physiology 265 : E699-E707. 1 January 1993

American Journal of Physiology Cell Physiology

Angiotensin 1-7 increases fiber cross sectional area and force in juvenile mouse skeletal muscle.
Albadrani, H., Ammar, T., Rajgara, R., Bader, M., Wiper-Bergeron, N. and Renaud, J.M.
American Journal of Physiology Cell Physiology 323 (6): C1681-C1696. December 2022

Alamandine acts via MrgD to induce AMPK/NO activation against Ang II hypertrophy in cardiomyocytes.
de Jesus, I.C.G., Scalzo, S., Alves, F., Marques, K., Rocha-Resende, C., Bader, M., Santos, R.A.S. and Guatimosim, S.
American Journal of Physiology Cell Physiology 314 (6): C702-C711. June 2018

American Journal of Physiology Endocrinology and Metabolism

Functional changes in the uterine artery precede the hypertensive phenotype in a transgenic model of hypertensive pregnancy.
Pulgar, V.M., Yamaleyeva, L.M., Varagic, J., McGee, C., Bader, M., Dechend, R. and Brosnihan, K.B.
American Journal of Physiology Endocrinology and Metabolism 309 (9): E811-E817. 1 November 2015

Physiological characterization of the hypertensive transgenic rat TGR(mREN2)27.
Lee, M.A., Boehm, M., Paul, M., Bader, M., Ganten, U. and Ganten, D.
American Journal of Physiology Endocrinology and Metabolism 270 : E919-E929. 1 January 1996

American Journal of Physiology Heart and Circulatory Physiology

The renin-angiotensin system: going beyond the classical paradigms.
Santos, R.A.S., Oudit, G.Y., Verano-Braga, T., Canta, G., Steckelings, U.M. and Bader, M.
American Journal of Physiology Heart and Circulatory Physiology 316 (5): H958-H970. May 2019

Genetic deletion of the alamandine receptor MrgD leads to dilated cardiomyopathy in mice.
Oliveira, A.C., Melo, M.B., Motta-Santos, D., Peluso, A.A., Souza-Neto, F., da Silva, R.F., Almeida, J.F.Q., Canta, G., Reis, A.M., Goncalves, G., Cerri, G.G., Coutinho, D., de Jesus, I.C.G., Guatimosim, S., Linhares, N.D., Alenina, N., Bader, M., Campagnole-Santos, M.J. and Santos, R.A.S.
American Journal of Physiology Heart and Circulatory Physiology 316 (1): H123-H133. January 2019

High aminopeptidase A activity contributes to blood pressure control in ob/ob mice by AT2 receptor-dependent mechanism.
Morais, R.L., Hilzendeger, A.M., Visniauskas, B., Todiras, M., Alenina, N., Mori, M.A., Araújo, R.C., Nakaie, C.R., Chagas, J.R., Carmona, A.., Bader, M. and Pesquero, J.B.
American Journal of Physiology Heart and Circulatory Physiology 312 (3): H437-H445. 1 March 2017

Cardiac angiotensin-(1-12) expression and systemic hypertension in rats expressing the human angiotensinogen gene.
Ferrario, C.M., VonCannon, J.L., Jiao, Y., Ahmad, S., Bader, M., Dell'Italia, L.J., Groban, L. and Varagic, J.
American Journal of Physiology Heart and Circulatory Physiology 310 (8): H995-H1002. 15 April 2016

Post-infarct sympathetic hyperactivity differentially stimulates expression of tyrosine hydroxylase and norepinephrine transporter.
Parrish, D.C., Gritman, K., Van Winkle, D.M., Woodward, W.R., Bader, M. and Habecker, B.A.
American Journal of Physiology Heart and Circulatory Physiology 294 (1): H99-H106. 1 January 2008

Expression of an angiotensin-(1-7)-producing fusion protein in rats induced marked changes in regional vascular resistance.
Botelho-Santos, G.A., Sampaio, W.O., Reudelhuber, T.L., Bader, M., Campagnole-Santos, M.J. and Santos, R.A.
American Journal of Physiology Heart and Circulatory Physiology 292 (5): H2485-H2490. 1 May 2007

Enhanced isoproterenol-induced cardiac hypertrophy in transgenic rats with low brain angiotensinogen.
Campos, L.A., Iliescu, R., Fontes, M.A.P., Schlegel, W.P., Bader, M. and Baltatu, O.C.
American Journal of Physiology Heart and Circulatory Physiology 291 (5): H2371-H2376. 1 November 2006

Rat corin gene: molecular cloning and reduced expression in experimental heart failure.
Langenickel, T.H., Pagel, I., Buttgereit, J., Tenner, K., Lindner, M., Dietz, R., Willenbrock, R. and Bader, M.
American Journal of Physiology Heart and Circulatory Physiology 287 (4): H1516-H1521. 1 January 2004

Tonin in rat heart with experimental hypertrophy.
Borges, J.C., Silva, J.A., Gomes, M.A., Lomez, E.S.L., Leite, K.M., Araujo, R.C., Bader, M., Pesquero, J.B. and Pesquero, J.L.
American Journal of Physiology Heart and Circulatory Physiology 284 (6): H2263-H2268. 1 June 2003

Functional, biochemical, and molecular investigations of renal kallikrein-kinin system in diabetic rats.
Tschoepe, C., Reinecke, A., Seidl, U., Yu, M., Gavriluk, V., Riester, U., Gohlke, P., Graf, K., Bader, M., Hilgenfeldt, U., Pesquero, J.B., Ritz, E. and Unger, T.
American Journal of Physiology Heart and Circulatory Physiology 277 (6 Pt 2): H2333-H2340. December 1999

American Journal of Physiology Lung Cellular and Molecular Physiology

Chronic allergic pulmonary inflammation is aggravated in angiotensin-(1-7) Mas receptor knockout mice.
Magalhaes, G.S., Rodrigues-Machado, M.G., Motta-Santos, D., Alenina, N., Bader, M., Santos, R.A.S., Barcelos, L.S. and Campagnole-Santos, M.J.
American Journal of Physiology Lung Cellular and Molecular Physiology 311 (6): L1141-L1148. 12 December 2016

American Journal of Physiology Regulatory Integrative and Comparative Physiology

Alamandine but not angiotensin-(1-7) produces cardiovascular effects at the rostral insular cortex.
Marins, F.R., Oliveira, A.C., Qadri, F., Motta-Santos, D., Alenina, N., Bader, M., Fontes, M.A.P. and Souza Santos, R.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 321 (3): R513-R521. 10 September 2021

Mas receptor deficiency is associated with worsening of lipid profile and severe hepatic steatosis in ApoE knockout mice.
Silva, A.R., Aguilar, E.C., Alvarez-Leite, J.I., da Silva, R.F., Arantes, R.M.E., Bader, M., Alenina, N., Pelli, G., Lenglet, S., Galan, K., Montecucco, F., Mach, F., Santos, S.H.S. and Santos, R.A.S.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 305 (11): R1323-R1330. December 2013

A role of the (pro)renin receptor in neuronal cell differentiation.
Contrepas, A., Walker, J., Koulakoff, A., Franek, K.J., Qadri, F., Giaume, C., Corvol, P., Schwartz, C.E. and Nguyen, G.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 297 (2): R250-R257. August 2009

Altered circadian rhythm reentrainment to light phase shifts in rats with low brain angiotensinogen.
Campos, L.A., Plehm, R., Cipolla-Neto, J., Bader, M. and Baltatu, O.C.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 290 (4): R1122-R1127. 1 April 2006

Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen.
Baltatu, O., Fontes, M.A.P., Campagnole-Santos, M.J., Caligiorni, S., Ganten, D., Santos, R.A.S. and Bader, M.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 280 (2): R428-R433. 1 January 2001

Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).
Monti, J., Schinke, M., Boehm, M., Ganten, D., Bader, M. and Bricca, G.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 280 (1): R233-R240. 1 January 2001

American Journal of Physiology Renal Physiology

B2 cells contribute to hypertension and natural killer cell activation possibly via AT1-AA in response to placental ischemia.
Herrock, O.T., Deer, E., Amaral, L.M., Campbell, N., Lemon, J., Ingram, N., Cornelius, D.C., Turner, T., Fitzgerald, S., Ibrahim, T., Dechend, R., Wallukat, G. and LaMarca, B.
American Journal of Physiology Renal Physiology 324 (2): F179-F192. February 2023

Calcineurin inhibitor cyclosporine a activates renal Na-K-Cl cotransporters via local and systemic mechanisms.
Blankenstein, K.I., Borschewski, A., Labes, R., Paliege, A., Boldt, C., McCormick, J.A., Ellison, D.H., Bader, M., Bachmann, S. and Mutig, K.
American Journal of Physiology Renal Physiology 312 (3): F489-F501. 2 March 2017

Demonstration of the functional impact of vasopressin signaling in the thick ascending limb by a targeted transgenic rat approach.
Mutig, K., Borowski, T., Boldt, C., Borschewski, A., Paliege, A., Popova, E., Bader, M. and Bachmann, S.
American Journal of Physiology Renal Physiology 311 (2): F411-F423. 1 August 2016

Developmental renin expression in mice with defective renin angiotensin system.
Machura, K., Steppan, D., Neubauer, B., Alenina, N., Coffman, T.M., Facemire, C.M., Hilgers, K.F., Eckardt, K.U., Wagner, C. and Kurtz, A.
American Journal of Physiology Renal Physiology 297 (5): F1371-F1380. November 2009

Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice.
Bachmann, S., Mutig, K., Bates, J., Welker, P., Geist, B., Gross, V., Luft, F.C., Alenina, N., Bader, M., Thiele, B.J., Prasadan, K., Raffi, H.S. and Kumar, S.
American Journal of Physiology Renal Physiology 288 (3): F559-F567. 1 January 2005

American Journal of Physiology: Heart and Circulatory Physiology

Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function.
Costa-Goncalves, A.C., Leite, R., Fraga-Silva, R.A., Pinheiro, S.V., Reis, A.B., Reis, F.M., Touyz, R.M., Webb, R.C., Alenina, N., Bader, M. and Santos, R.A.S.
American Journal of Physiology: Heart and Circulatory Physiology 293 (4): H2588-H2596. 1 October 2007

Analytical Chemistry

Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.
Ciruela, F., Burgueno, J., Casado, V.V., Canals, M., Marcellino, D., Goldberg, S.R., Bader, M., Fuxe, K., Agnati, L.F., Lluis, C., Franco, R., Ferre, S. and Woods, A.S.
Analytical Chemistry 76 (18): 5354-5363. 1 January 2004

Anesthesiology

Impaired nociception and peripheral opioid antinociception in mice lacking both kinin b1 and b2 receptors.
Cayla, C., Labuz, D., Machelska, H., Bader, M., Schaefer, M. and Stein, C.
Anesthesiology 116 (2): 448-457. February 2012

Angiogenesis

The role of receptor MAS in microglia-driven retinal vascular development.
Foulquier, S., Caolo, V., Swennen, G., Milanova, I., Reinhold, S., Recarti, C., Alenina, N., Bader, M., Steckelings, U M., Vanmierlo, T., Post, M.J., Jones, E.A., van Oostenbrugge, R.J. and Unger, T.
Angiogenesis 22 (4): 481-189. November 2019

Angiotensin-(1-7)

Genetic models.
Alenina, N. and Bader, M.
In: Angiotensin-(1-7) : a comprehensive review. Springer, Cham, 35-51. ISBN 978-3-030-22695-4 2019

Annals of the Rheumatic Diseases

The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents.
Silva, C.R., Oliveira, S.M., Hoffmeister, C., Funck, V., Guerra, G.P., Trevisan, G., Tonello, R., Rossato, M.F., Pesquero, J.B., Bader, M., Oliveira, M.S., McDougall, J.J. and Ferreira, J.
Annals of the Rheumatic Diseases 75 (1): 260-268. January 2016

Annual Review of Pharmacology and Toxicology

Tissue renin-angiotensin-aldosterone systems: Targets for pharmacological therapy.
Bader, M.
Annual Review of Pharmacology and Toxicology 50 : 439-65. 2010

Arteriosclerosis Thrombosis and Vascular Biology

Ly6C(high) monocytes oscillate in the heart during homeostasis and after myocardial infarction.
Schloss, M.J., Hilby, M., Nitz, K., Guillamat Prats, R., Ferraro, B., Leoni, G., Soehnlein, O., Kessler, T., He, W., Luckow, B., Horckmans, M., Weber, C., Duchene, J. and Steffens, S.
Arteriosclerosis Thrombosis and Vascular Biology 37 (9): 1640-1645. September 2017

Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7).
Santos, S.H., Felix Braga, J., Mario, E.G., Porto, L.C., Rodrigues-Machado, M.D., Murari, A., Botion, L.M., Alenina, N., Bader, M. and Santos, R.A.
Arteriosclerosis Thrombosis and Vascular Biology 30 (5): 953-61. May 2010

Kallikrein-kinin system in neovascularization.
Bader, M.
Arteriosclerosis Thrombosis and Vascular Biology 29 (5): 617-619. May 2009

Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells.
Batenburg, W.W., de Bruin, R.J., van Gool, J.M., Mueller, D.N., Bader, M., Nguyen, G. and Danser, A.H.
Arteriosclerosis Thrombosis and Vascular Biology 28 (6): 1151-1157. June 2008

Mass-spectrometric identification of a novel angiotensin peptide in human plasma.
Jankowski, V., Vanholder, R., van der Giet, M., Toelle, M., Karadogan, S., Gobom, J., Furkert, J., Oksche, A., Krause, E., Tran, T.N., Tepel, M., Schuchardt, M., Schlueter, H., Wiedon, A., Beyermann, M., Bader, M., Todiras, M., Zidek, W. and Jankowski, J.
Arteriosclerosis Thrombosis and Vascular Biology 27 (2): 297-302. February 2007

Arzneimittelforschung

The renin-angiotensin system in the brain. Localization and functional significance.
Paul, M., Bader, M., Steckelings, U.M., Voigtlaender, T. and Ganten, D.
Arzneimittelforschung 43 : 207-213. 1 January 1993

BMC Developmental Biology

Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming.
Grohmann, M., Spada, F., Schermelleh, L., Alenina, N., Bader, M., Cardoso, M.C. and Leonhardt, H.
BMC Developmental Biology 5 : 18. 24 August 2005

BMC Genomics

Large-scale mapping of mutations affecting zebrafish development.
Geisler, R., Rauch, G.J., Geiger-Rudolph, S., Albrecht, A., van Bebber, F., Berger, A., Busch-Nentwich, E., Dahm, R., Dekens, M.P., Dooley, C., Elli, A.F., Gehring, I., Geiger, H., Geisler, M., Glaser, S., Holley, S., Huber, M., Kerr, A., Kirn, A., Knirsch, M., Konantz, M., Kuechler, A.M., Maderspacher, F., Neuhauss, S.C., Nicolson, T., Ober, E.A., Praeg, E., Ray, R., Rentzsch, B., Rick, J.M., Rief, E., Schauerte, H.E., Schepp, C.P., Schoenberger, U., Schonthaler, H.B., Seiler, C., Sidi, S., Soellner, C., Wehner, A., Weiler, C. and Nuesslein-Volhard, C.
BMC Genomics 8 : 11. 9 January 2007

BMC Medical Education

A student-centered approach for developing active learning: the construction of physical models as a teaching tool in medical physiology.
Rezende-Filho, F.M., Da Fonseca, L.J.S., Nunes-Souza, V., Da Silva Guedes, G. and Rabelo, L.A.
BMC Medical Education 14 : 189. 15 September 2014

Behavioural Brain Research

Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L., Peeva, P., Ramos-Prats, A., Alenina, N., Winter, Y. and Rivalan, M.
Behavioural Brain Research 377 : 112188. 13 January 2020

Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis.
Mosienko, V., Beis, D., Pasqualetti, M., Waider, J., Matthes, S., Qadri, F., Bader, M. and Alenina, N.
Behavioural Brain Research 277 (SI): 78-88. 15 January 2015

The role of serotonin in adult hippocampal neurogenesis.
Alenina, N. and Klempin, F.
Behavioural Brain Research 277 : 49-57. 15 January 2015

Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen.
Kangussu, L.M., Almeida-Santos, A.F., Bader, M., Alenina, N., Fontes, M.A., Santos, R.A., Aguiar, D.C. and Campagnole-Santos, M.J.
Behavioural Brain Research 257 : 25-30. 15 November 2013

Sex specific behavioural alterations in Mas-deficient mice.
Walther, T., Voigt, J.P., Fink, H. and Bader, M.
Behavioural Brain Research 107 (1-2): 105-109. 1 January 2000

Learning and anxiety in angiotensin-deficient mice.
Walther, T., Voigt, J.P., Fukamizu, A., Fink, H. and Bader, M.
Behavioural Brain Research 100 : 1-4. 1 April 1999

BioFactors

Transforming growth factor type-β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular dystrophies.
Cofre, C., Acuna, M.J., Contreras, O., Morales, M.G., Riquelme, C., Bader, M., Santos, R., Cabello-Verrugio, C. and Brandan, E.
BioFactors 41 (2): 111-120. March 2015

Biochemical Pharmacology

The contribution of the AT1 receptor to erythropoiesis.
Rodrigues, A.F. and Bader, M.
Biochemical Pharmacology 217 : 115805. November 2023

Functional assay for assessment of agonistic or antagonistic activity of angiotensin AT(2) receptor ligands reveals that EMA401 and PD123319 have agonistic properties.
Peluso, A.A., Souza Silva, I.M., Villela, D.C., Hansen, P.B.L., Hallberg, A., Bader, M., Santos, R., Sumners, C. and Muscha Steckelings, U.
Biochemical Pharmacology 216 : 115793. October 2023

A unique central tryptophan hydroxylase isoform.
Walther, D.J. and Bader, M.
Biochemical Pharmacology 66 (9): 1673-1680. 1 November 2003

Biochemical and Biophysical Research Communications

Role of Gpnmb in atherosclerosis of female mice.
Nickl, B., Qadri, F. and Bader, M.
Biochemical and Biophysical Research Communications 621 : 20-24. 17 September 2022

Dual effect of chemokine CCL7/MCP-3 in the development of renal tubulointerstitial fibrosis.
Gonzalez, J., Mouttalib, S., Delage, C., Calise, D., Maoret, J.J., Pradere, J.P., Klein, J., Buffin-Meyer, B., Van der Veen, B., Charo, I.F., Heeringa, P., Duchene, J., Bascands, J.L. and Schanstra, J.P.
Biochemical and Biophysical Research Communications 438 (2): 257-263. 23 August 2013

A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation.
Folkesson, R., Malkiewicz, K., Kloskowska, E., Nilsson, T., Popova, E., Bogdanovic, N., Ganten, U., Ganten, D., Bader, M., Winblad, B. and Benedikz, E.
Biochemical and Biophysical Research Communications 358 (3): 777-782. 6 July 2007

Imprinting of the murine Mas protooncogene is restricted to its antisense RNA.
Alenina, N., Bader, M. and Walther, T.
Biochemical and Biophysical Research Communications 290 : 1072-1078. 1 January 2002

Alternative splicing of the mRNA coding for the human endothelial angiotensin-converting enzyme: a new mechanism for solubilization.
Sugimura, K., Tian, X.L., Hoffmann, S., Ganten, D. and Bader, M.
Biochemical and Biophysical Research Communications 247 : 466-472. 1 January 1998

Molecular cloning and functional characterization of a mouse bradykinin B1 receptor gene.
Pesquero, J.B., Pesquero, J.L., Oliveira, S.M., Roscher, A.A., Metzger, R., Ganten, D. and Bader, M.
Biochemical and Biophysical Research Communications 220 (1): 219-225. 1 January 1996

Extra-hepatic transcription of plasma prekallikrein gene in human and rat tissues.
Ciechanowicz, A., Bader, M., Wagner, J. and Ganten, D.
Biochemical and Biophysical Research Communications 197 : 1370-1376. 1 January 1993

Biochimica et Biophysica Acta - Molecular Cell Research

Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway.
Depping, R., Steinhoff, A., Schindler, S.G., Friedrich, B., Fagerlund, R., Metzen, E., Hartmann, E. and Koehler, M.
Biochimica et Biophysica Acta - Molecular Cell Research 1783 (3): 394-404. March 2008

Biological Chemistry

Acute hypothalamo-pituitary-adrenal axis response to LPS-induced endotoxemia: expression pattern of kinin type B1 and B2 receptors.
Qadri, F., Rimmele, F., Mallis, L., Häuser, W., Dendorfer, A., Jöhren, O., Dominiak, P., Leeb-Lundberg, L.M.F. and Bader, M.
Biological Chemistry 397 (2): 97-109. January 2016

Kinin B1 receptor gene ablation affects hypothalamic CART production.
Torres, H.A.M., Motta, F.L., Sales, V.M., Batista, C., da Silva, J.M., Vignoli, T., Barnabé, G.F., Goeldner, F.O., D'Almeida, V., Bittencourt, J.C., Sinigaglia-Coimbra, R., Bader, M., Mello, L.E.A.M. and Pesquero, J.B.
Biological Chemistry 394 (7): 901-908. July 2013

Role of kinin B2 receptors in opioid-induced-hyperalgesia in inflammatory pain in mice.
Grastilleur, S., Mouledous, L., Bedel, J., Etcheverry, J., Bader, M., Girolami, J.P., Fourcade, O., Frances, B. and Minville, V.
Biological Chemistry 394 (3): 361-368. March 2013

Increased blood pressure and water intake in transgenic mice expressing rat tonin in the brain.
Cardoso, C.C., Alenina, N., Ferreira, A.J., Qadri, F., Lima, M.P., Gross, V., Todiras, M., Pesquero, J.B., Pesquero, J.L. and Bader, M.
Biological Chemistry 391 (4): 435-441. April 2010

Signal transduction in CHO-cells stably transfected with domain-selective forms of murine ACE.
Sun, X., Rentzsch, B., Gong, M., Eichhorst, J., Pankow, K., Papsdorf, G., Maul, B., Bader, M. and Siems, W.E.
Biological Chemistry 391 (2-3): 235-244. February 2010

Cross talk between kinin and angiotensin II receptors in mouse abdominal aorta.
Rodrigues, E.S., Martin, R.P., Felipe, S.A., Bader, M., Oliveira, S.M. and Shimuta, S.I.
Biological Chemistry 390 (9): 907-913. September 2009

Doxorubicin cardiomyopathy-induced inflammation and apoptosis are attenuated by gene deletion of the kinin B1 receptor.
Westermann, D., Lettau, O., Sobirey, M., Riad, A., Bader, M., Schultheiss, H.P. and Tschoepe, C.
Biological Chemistry 389 (6): 713-718. June 2008

Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function.
Araújo, R.C., Mori, M.A., Merino, V.F., Bascands, J.L., Schanstra, J.P., Zollner, R.L., Villela, C.A., Nakaie, C.R., Paiva, A.C., Pesquero, J.L., Bader, M. and Pesquero, J.B.
Biological Chemistry 387 (4): 431-436. April 2006

Genetically altered animal models in the kallikrein-kinin system.
Pesquero, J.B. and Bader, M.
Biological Chemistry 387 (2): 119-126. 9 February 2006

Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genes.
Bachvarov, D., Bachvarova, M., Koumangaye, R., Klein, J., Pesquero, J.B., Neau, E., Bader, M., Schanstra, J.P. and Bascands, J.L.
Biological Chemistry 387 (1): 15-22. January 2006

Molecular structure and transcriptional regulation by nuclear factor-kappaB of the mouse kinin B1 receptor gene.
Merino, V.F., Silva, J.A., Araújo, R.C., Avellar, M.C., Bascands, J.L., Schanstra, J.P., Paiva, A.C., Bader, M. and Pesquero, J.B.
Biological Chemistry 386 (6): 515-522. 1 June 2005

Structure and expression of two kininogen genes in mice.
Cardoso, C.C., Garrett, T., Cayla, C., Meneton, P., Pesquero, J.B. and Bader, M.
Biological Chemistry 385 (3-4): 295-301. 1 January 2004

Molecular structure and alternative splicing of the human carboxypeptidase M gene.
Pessoa, L.G., da Silva, I.D.G., Baptista, H.A., Pesquero, J.L., Paiva, A.C.M., Bader, M. and Pesquero, J.B.
Biological Chemistry 383 : 263-269. 1 January 2002

Altered neutrophil homeostasis in kinin B1 receptor deficient mice.
Araújo, R.C., Kettritz, R., Fichtner, I., Paiva, A.C.M., Pesquero, J.B. and Bader, M.
Biological Chemistry 382 : 91-95. 1 January 2001

Biology Letters

Brain serotonin deficiency leads to social communication deficits in mice.
Beis, D., Holzwarth, K., Flinders, M., Mosienko, V., Bader, M., Wöhr, M. and Alenina, N.
Biology Letters 11 (3): 20150057. March 2015

Biology of Reproduction

Full-term development of rat after transfer of nuclei from two-cell stage embryos.
Popova, E., Bader, M. and Krivokharchenko, A.
Biology of Reproduction 75 (4): 524-530. October 2006

Development of parthenogenetic rat embryos.
Krivokharchenko, A., Popova, E., Zaitseva, I., Vil'ianovich, L., Ganten, D. and Bader, M.
Biology of Reproduction 68 (3): 829-836. 1 March 2003

Biology of Sex Differences

Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states.
Madalli, S., Beyrau, M., Whiteford, J., Duchene, J., Singh Nandhra, I., Patel, N.S.A., Motwani, M.P., Gilroy, D.W., Thiemermann, C., Nourshargh, S. and Scotland, R.S.
Biology of Sex Differences 6 : 27. 26 November 2015

Biomedicines

Cortisol dose-dependently impairs migration and tube-like formation in a trophoblast cell line and modulates inflammatory and angiogenic genes.
Húngaro, T.G.R, Gregnani, M.F., Alves-Silva, T., Herse, F., Alenina, N., Bader, M. and Araújo, R.C.
Biomedicines 9 (8): 980. August 2021

Biomolecules

Thimet oligopeptidase (EC 3.4.24.15) key functions suggested by knockout mice phenotype characterization.
Santos, N.B.D., Franco, R.D., Camarini, R., Munhoz, C.D., Eichler, R.A.S., Gewehr, M.C.F., Reckziegel, P., Llanos, R.P., Dale, C.S., da Silva, V.R.O., Borges, V.F., Lima, B.H.F., Cunha, F.Q., Visniauskas, B., Chagas, J.R., Tufik, S., Peres, F.F., Abilio, V.C., Florio, J.C., Iwai, L.K., Rioli, V., Presoto, B.C., Guimaraes, A.O., Pesquero, J.B., Bader, M., Castro, L.M. and Ferro, E.S.
Biomolecules 9 (8): 382. 19 August 2019

Biophysical Journal

Cardiomyopathy mutations reveal variable region of myosin converter as major element of cross-bridge compliance.
Seebohm, B., Matinmehr, F., Koehler, J., Francino, A., Navarro-Lopez, F., Perrot, A., Oezcelik, C., McKenna, W.J., Brenner, B. and Kraft, T.
Biophysical Journal 97 (3): 806-824. 5 August 2009

Blood

Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Duerschmied, D., Suidan, G.L., Demers, M., Herr, N., Carbo, C., Brill, A., Cifuni, S.M., Mauler, M., Cicko, S., Bader, M., Idzko, M., Bode, C. and Wagner, D.D.
Blood 121 (6): 1008-1015. 7 February 2013

Brain Research

Cardiovascular responses evoked by activation or blockade of GABA(A) receptors in the hypothalamic PVN are attenuated in transgenic rats with low brain angiotensinogen.
Gomes da Silva, A.Q., Xavier, C.H., Campagnole-Santos, M.J., Caligiorne, S.M., Baltatu, O.C., Bader, M., Santos, R.A. and Fontes, M.A.
Brain Research 1448 : 101-110. 11 April 2012

Brain angiotensin and anxiety-related behavior: The transgenic rat TGR(ASrAOGEN)680.
Voigt, J.P., Hoertnagl, H., Rex, A., van Hove, L., Bader, M. and Fink, H.
Brain Research 1046 (1-2): 145-156. 1 January 2005

Role of kinin B1 and B2 receptors in the development of pilocarpine model of epilepsy.
Arganaraz, G.A., Perosa, S.R., Lencioni, E.C., Bader, M., Cavalheiro, E.A., da Graca Naffah-Mazzacoratti, M., Pesquero, J.B. and Silva, J.A.
Brain Research 1013 (1): 30-39. 1 January 2004

The synthesis and distribution of the kinin B1 and B2 receptors are modified in the hippocampus of rats submitted to pilocarpine model of epilepsy.
Arganaraz, G.A., Silva, J.A., Perosa, S.R., Pessoa, L.G., Carvalho, F.F., Bascands, J.L., Bader, M., Trindade, E.D., Amado, D., Cavalheiro, E.A., Pesquero, J.B. and Naffah-Mazzacoratti, M.D.
Brain Research 1006 (1): 114-125. 1 January 2004

High levels of human chymase expression in the pineal and pituitary glands.
Baltatu, O., Nishimura, H., Hoffmann, S., Stoltenburg, G., Haulica, I.D., Lippoldt, A., Ganten, D. and Urata, H.
Brain Research 752 : 269-278. 1 January 1997

Behaviour of the transgenic (mRen2)27 rat.
Wilson, W., Voigt, P., Bader, M., Marsden, C.A. and Fink, H.
Brain Research 729 : 1-9. 1 January 1996

Brain Research Bulletin

Transgenic rat with overproduction of ubiquitous angiotensin-(1-7) presents neuroprotection in a model of ischemia and reperfusion.
Kangussu, L.M., Almeida-Santos, A.F., Fernandes, L.F., Alenina, N., Bader, M., Santos, R.A.S., Massensini, A.R. and Campagnole-Santos, M.J.
Brain Research Bulletin 192 : 184-191. January 2023

Brain Structure & Function

Bradykinin B2 receptor is essential to running-induced cell proliferation in the adult mouse hippocampus.
Wasinski, F., Oliveira Batista, R., Bader, M., Araujo, R.C. and Klempin, F.
Brain Structure & Function 223 (8): 3901-3907. November 2018

ATP6AP2 over-expression causes morphological alterations in the hippocampus and in hippocampus-related behaviour.
Bracke, A., Schäfer, S., von Bohlen und Halbach, V., Klempin, F., Bente, K., Bracke, K., Staar, D., van den Brandt, J., Harzsch, S., Bader, M., Wenzel, U.O., Peters, J. and von Bohlen und Halbach, O.
Brain Structure & Function 223 (5): 2287-2302. June 2018

Brazilian Journal of Medical and Biological Research

Regulation of the kinin receptors after induction of myocardial infarction: a mini-review.
Tschoepe, C., Heringer-Walther, S. and Walther, T.
Brazilian Journal of Medical and Biological Research 33 (6): 701-708. 1 June 2000

Altered heart rate and blood pressure variability in mice lacking the Mas protooncogene.
Walther, T., Wessel, N., Kang, N., Sander, A., Tschoepe, C., Malberg, H., Bader, M. and Voss, A.
Brazilian Journal of Medical and Biological Research 33 (1): 1-9. 1 January 2000

Molecular biology of the kallikrein-kinin system: from structure to function.
Pesquero, J.B. and Bader, M.
Brazilian Journal of Medical and Biological Research 31 : 1197-1203. 1 September 1998

Transgenic animal models for the functional analysis of vasoactive peptides.
Bader, M.
Brazilian Journal of Medical and Biological Research 31 : 1171-1183. 1 September 1998

Breast Cancer Research

A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland.
Gordon, K.E., Binas, B., Chapman, R.S., Kurian, K.M., Clarkson, R.W.E., Clark, A.J., Lane, E.B. and Watson, C.J.
Breast Cancer Research 2 (3): 222-235. 1 January 2000

British Journal of Pharmacology

Angiotensin deficient FVB/N mice are normotensive.
Rodrigues, A.F., Todiras, M., Qadri, F., Alenina, N. and Bader, M.
British Journal of Pharmacology 180 (14): 1843-1861. July 2023

B(1) and B(2) kinin receptor blockade improves psoriasis-like disease.
da Silva Soley, B., Silva, L.M., Mendes, D.A.G.B., Báfica, A., Pesquero, J.B., Bader, M., Witherden, D.A., Havran, W.L., Calixto, J.B., Otuki, M.F. and Cabrini, D.A.
British Journal of Pharmacology 177 (15): 3535-3551. August 2020

The brain renin-angiotensin system plays a crucial role in regulating body weight in diet-induced rat obesity.
Winkler, M., Schuchard, J., Stölting, I., Vogt, F.M., Barkhausen, J., Thorns, C., Bader, M. and Raasch, W.
British Journal of Pharmacology 173 (10): 1602-1617. May 2016

Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway.
Schuchard, J., Winkler, M., Stölting, I., Schuster, F., Vogt, F.M., Barkhausen, J., Thorns, C., Santos, R.A., Bader, M. and Raasch, W.
British Journal of Pharmacology 172 (15): 3764-3778. August 2015

Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation.
Chan, M.V., Bubb, K.J., Noyce, A., Villar, I.C., Duchene, J., Hobbs, A.J., Scotland, R.S. and Ahluwalia, A.
British Journal of Pharmacology 167 (4): 805-817. October 2012

Upregulation of bradykinin B1-receptor expression after myocardial infarction.
Tschoepe, C., Heringer-Walther, S., Koch, M., Spillmann, F., Wendorf, M., Leitner, E., Schultheiss, H.P. and Walther, T.
British Journal of Pharmacology 129 (8): 1537-1538. 1 April 2000

Heat stress-induced B1 receptor synthesis in the rat: an ex vivo study.
Lagneux, C., Innocenti-Francillard, P., Godin-Ribuot, D., Bader, M. and Ribuot, C.
British Journal of Pharmacology 125 : 812-816. 1 October 1998

CNS Neuroscience & Therapeutics

Locus coeruleus dysfunction in transgenic rats with low brain angiotensinogen.
Ogier, M., Bricca, G., Bader, M. and Bezin, L.
CNS Neuroscience & Therapeutics 22 (3): 230-237. March 2016

Canadian Journal of Physiology and Pharmacology

Improved cardiovascular autonomic modulation in transgenic rats expressing an Ang-(1-7)-producing fusion protein.
Dartora, D.R., Irigoyen, M.C., Casali, K.R., Moraes-Silva, I.C., Bertagnolli, M., Bader, M. and Santos, R.
Canadian Journal of Physiology and Pharmacology 95 (9): 993-998. September 2017

Cance

7-hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors.
Walther, D.J., Peter, J.U. and Bader, M.
Cance 94 (12): 3135-3140. 1 January 2002

Cancer Research

Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts.
Nocito, A., Dahm, F., Jochum, W., Jang, J.H., Georgiev, P., Bader, M., Graf, R. and Clavien, P.A.
Cancer Research 68 (13): 5152-5158. 1 July 2008

Cardiovascular Hormone Systems

Cardiovascular hormone systems.
Bader, M., ed.
Wiley-Blackwell, 1-433. ISBN 9783527319206 10 September 2008

Kinins.
Macedo de Oliveira, S., de Picoli Souza, K., Bader, M. and Pesquero, J.B.
In: Cardiovascular Hormone Systems. Wiley-Blackwell, 101-123. ISBN 9783527319206 10 September 2008

Preface.
Bader, M.
Cardiovascular Hormone Systems : xvii-xviii. 10 September 2008

Serotonin.
Bader, M.
In: Cardiovascular Hormone Systems. Wiley-Blackwell, 209-231. ISBN 9783527319206 10 September 2008

Cardiovascular Research

Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G., Bartolomaeus, H., Rauch, A., Chen, C.Y., N'Diaye, G., Löber, U., Bartolomaeus, T.U.P., Fritsche-Guenther, R., Rodrigues, A.F., Yarritu, A., Zhong, C., Fei, L., Tsvetkov, D., Todiras, M., Park, J.K., Markó, L., Maifeld, A., Patzak, A., Bader, M., Kempa, S., Kirwan, J.A., Forslund, S.K., Müller, D.N. and Wilck, N.
Cardiovascular Research 119 (6): 1441-1452. May 2023

Targeting angiotensin type 2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice.
Mohammed, M., Johnson, D.N., Wang, L.A., Harden, S.W., Sheng, W., Spector, E.A., Elsaafien, K., Bader, M., Steckelings, U.M., Scott, K.A., Frazier, C.J., Sumners, C., Krause, E.G. and de Kloet, A.D.
Cardiovascular Research 118 (3): 883-896. 21 February 2022

C-type natriuretic peptide and NPR-B signalling inhibits cardiac sympathetic neurotransmission and autonomic function.
Buttgereit, J., Shanks, J., Li, D., Hao, G., Athwal, A., Langenickel, T.H., Wright, H., da Costa Goncalves, A.C., Monti, J., Plehm, R., Popova, E., Qadri, F., Lapidus, I., Ryan, B., Özcelik, C., Paterson, D.J., Bader, M. and Herring, N.
Cardiovascular Research 112 (3): 637-644. December 2016

Controlling cardiomyocyte length: The role of renin and PPAR-γ.
Hinrichs, S., Heger, J., Schreckenberg, R., Wenzel, S., Euler, G., Arens, C., Bader, M., Rosenkranz, S., Caglayan, E. and Schlueter, K.D.
Cardiovascular Research 89 (2): 344-352. 1 February 2011

Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol.
Wendt, N., Schulz, A., Qadri, F., Bolbrinker, J., Kossmehl, P., Winkler, K., Stoll, M., Vetter, R. and Kreutz, R.
Cardiovascular Research 81 (3): 618-626. 15 February 2009

Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3β activation.
Li, H.J., Yin, H., Yao, Y.Y., Shen, B., Bader, M., Chao, L. and Chao, J.
Cardiovascular Research 73 (1): 130-142. 1 January 2007

Cell

Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity.
Batlle, D., Monteil, V., Garreta, E., Hassler, L., Wysocki, J., Chandar, V., Schwartz, R.E., Mirazimi, A., Montserrat, N., Bader, M. and Penninger, J.M.
Cell 185 (11): 1837-1839. 26 May 2022

Serotonylation of small GTPases is a signal transduction pathway that triggers platelet α-granule release.
Walther, D.J., Peter, J.U., Winter, S., Hoeltje, M., Paulmann, N., Grohmann, M., Vowinckel, J., Alamo-Bethencourt, V., Wilhelm, C.S., Ahnert-Hilger, G. and Bader, M.
Cell 115 (7): 851-862. 1 January 2003

An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D-3.
Nykjaer, A., Dragun, D., Walther, D., Vorum, H., Jacobsen, C., Herz, J., Melsen, F., Christensen, E.I. and Willnow, T.E.
Cell 96 (4): 507-515. 19 February 1999

Cell Cycle

Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells.
Fishman, V.S., Shnayder, T.A., Orishchenko, K.E., Bader, M., Alenina, N. and Serov, O.L.
Cell Cycle 14 (8): 1188-1196. 15 April 2015

Stable maintenance of de novo assembled human artificial chromosomes in embryonic stem cells and their differentiated progeny in mice.
Liskovykh, M., Ponomartsev, S., Popova, E., Bader, M., Kouprina, N., Larionov, V., Alenina, N. and Tomilin, A.
Cell Cycle 14 (8): 1268-1273. 15 April 2015

Cell Reports

Cellular importin-α3 expression dynamics in the lung regulate antiviral response pathways against influenza a virus infection.
Thiele, S., Stanelle-Bertram, S., Beck, S., Kouassi, N., Zickler, M., Müller, M., Tuku, B., Resa-Infante, P., van Riel, D., Alawi, M., Günther, T., Rother, F., Hügel, S., Reimering, S., McHardy, A., Grundhoff, A., Brune, W., Osterhaus, A., Bader, M., Hartmann, E. and Gabriel, G.
Cell Reports 31 (3): 107549. 21 April 2020

Importin α5 regulates anxiety through MeCP2 and sphingosine kinase 1.
Panayotis, N., Sheinin, A., Dagan, S.Y., Tsoory, M.M., Rother, F., Vadhvani, M., Meshcheriakova, A., Koley, S., Marvaldi, L., Song, D.A., Reuveny, E., Eickholt, B.J., Hartmann, E., Bader, M., Michaelevski, I. and Fainzilber, M.
Cell Reports 25 (11): 3169-3179. 11 December 2018

Cell Research

Low immunogenicity of endothelial derivatives from rat embryonic stem cell-like cells.
Ladhoff, J., Bader, M., Broesel, S., Effenberger, E., Westermann, D., Volk, H.D. and Seifert, M.
Cell Research 19 (4): 507-518. April 2009

Cell and Tissue Biology

Generation of rat-induced pluripotent stem cells: reprogramming and culture medium.
Liskovykh, M.A., Chuykin, I.A., Ranjan, A., Safina, D.A., Tolkunova, E.N., Minina, Y.M., Zhdanova, N.S., Dyban, P.A., Mullins, J.J., Kostyleva, E.I., Chikhirzhina, E.V., Bader, M., Alenina, N. and Tomilin, A.N.
Cell and Tissue Biology 6 (2): 115-121. April 2012

Genetic manipulations and examination of differentiation properties of rat induced pluripotent cells.
Liskovykh, M.A., Chuykin, I.A., Ranjan, A., Popova, E., Tolkunova, E.N., Chechik, L.L., Malinin, A.Y., Morozova, A.V., Mosienko, V., Bader, M., Alenina, N. and Tomilin, A.N.
Cell and Tissue Biology 6 (2): 122-127. April 2012

Cells

Tph2 gene expression defines ethanol drinking behavior in mice.
Zaniewska, M., Mosienko, V., Bader, M. and Alenina, N.
Cells 11 (5): 874. 3 March 2022

Enduring effects of conditional brain serotonin knockdown, followed by recovery, on adult rat neurogenesis and behavior.
Sidorova, M., Kronenberg, G., Matthes, S., Petermann, M., Hellweg, R., Tuchina, O., Bader, M., Alenina, N. and Klempin, F.
Cells 10 (11): 3240. 19 November 2021

Transfer of synthetic human chromosome into human induced pluripotent stem cells for biomedical applications.
Sinenko, S.A., Skvortsova, E.V., Liskovykh, M.A., Ponomartsev, S.V., Kuzmin, A.A., Khudiakov, A.A., Malashicheva, A.B., Alenina, N., Larionov, V., Kouprina, N. and Tomilin, A.N.
Cells 7 (12): 261. 8 December 2018

Cellular and Molecular Life Sciences

Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response.
Klempin, F., Mosienko, V., Matthes, S., Villela, D.C., Todiras, M., Penninger, J.M., Bader, M., Santos, R.A.S. and Alenina, N.
Cellular and Molecular Life Sciences 75 (19): 3625-3634. October 2018

Chinese Medical Journal

Progress in molecular medicine. From experimental genetics to the treatment of hypertensive patients.
Ganten, D., Kreutz, R., Bader, M. and Wagner, J.
Chinese Medical Journal 106 : 375-384. 1 January 1993

Circulation

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M., Mücke, M.B., Pallien, T., Markó, L., Sholokh, A., Schächterle, C., Aydin, A., Kidd, A., Walter, S., Esmati, Y., McMurray, B.J., Lato, D.F., Sunaga-Franze, D.Y., Dierks, P.H., Flores, B.I.M., Walker-Gray, R., Gong, M., Merticariu, C., Zühlke, K., Russwurm, M., Liu, T., Batolomaeus, T.U.P., Pautz, S., Schelenz, S., Taube, M., Napieczynska, H., Heuser, A., Eichhorst, J., Lehmann, M., Miller, D.C., Diecke, S., Qadri, F., Popova, E., Langanki, R., Movsesian, M.A., Herberg, F.W., Forslund, S.K., Müller, D.N., Borodina, T., Maass, P.G., Bähring, S., Hübner, N., Bader, M. and Klussmann, E.
Circulation 146 (23): 1758-1778. 6 December 2022

Phosphodiesterase 3A and arterial hypertension.
Ercu, M., Markó, L., Schächterle, C., Tsvetkov, D., Cui, Y., Maghsodi, S., Bartolomaeus, T.U.P., Maass, P.G., Zühlke, K., Gregersen, N., Hübner, N., Hodge, R., Mühl, A., Pohl, B., Molé-Illas, R., Geelhaar, A., Walter, S., Napieczynska, H., Schelenz, S., Taube, M., Heuser, A., Anistan, Y.M., Qadri, F., Todiras, M., Plehm, R., Popova, E., Langanki, R., Eichhorst, J., Lehmann, M., Wiesner, B., Russwurm, M., Forslund, S.K., Kamer, I., Müller, D.N., Gollasch, M., Aydin, A., Bähring, S., Bader, M., Luft, F.C. and Klussmann, E.
Circulation 142 (2): 133-149. 14 July 2020

Novel insights into the critical role of bradykinin and the kinin B2 receptor for vascular recruitment of circulating endothelial repair-promoting mononuclear cell subsets: alterations in patients with coronary disease.
Kränkel, N., Kuschnerus, K., Müller, M., Speer, T., Mocharla, P., Madeddu, P., Bader, M., Lüscher, T.F. and Landmesser, U.
Circulation 127 (5): 594-603. 5 February 2013

Regulatory T cells ameliorate angiotensin II-induced cardiac damage.
Kvakan, H., Kleinewietfeld, M., Qadri, F., Park, J.K., Fischer, R., Schwarz, I., Rahn, H.P., Plehm, R., Wellner, M., Elitok, S., Gratze, P., Dechend, R., Luft, F.C. and Mueller, D.N.
Circulation 119 (22): 2904-2912. 9 June 2009

Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice.
Xi, L., Das, A., Zhao, Z.Q., Merino, V.F., Bader, M. and Kukreja, R.C.
Circulation 118 (14 Suppl): S32-S37. 30 September 2008

Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice.
Dempsie, Y., Morecroft, I., Welsh, D.J., Macritchie, N.A., Herold, N., Loughlin, L., Nilsen, M., Peacock, A.J., Harmar, A., Bader, M. and Maclean, M.R.
Circulation 2008 (117): 2928-2937. 3 June 2008

Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
Gratze, P., Dechend, R., Stocker, C., Park, J.K., Feldt, S., Shagdarsuren, E., Wellner, M., Gueler, F., Rong, S., Gross, V., Obst, M., Plehm, R., Alenina, N., Zenclussen, A., Titze, J., Small, K., Yokota, Y., Zenke, M., Luft, F.C. and Mueller, D.N.
Circulation 117 (20): 2645-2656. 20 May 2008

Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease.
Walther, T., Tschoepe, C., Sterner-Kock, A., Westermann, D., Heringer-Walther, S., Riad, A., Nikolic, A., Wang, Y., Ebermann, L., Siems, W.E., Bader, M., Shakibaei, M., Schultheiss, H.P. and Doerner, A.
Circulation 115 (3): 333-344. 23 January 2007

Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress.
Donath, S., Li, P., Willenbockel, C., Al-Saadi, N., Gross, V., Willnow, T.E., Bader, M., Martin, U., Bauersachs, J., Wollert, K.C., Dietz, R. and von Harsdorf, R.
Circulation 113 (9): 1203-1212. 7 March 2006

Targeting kinin B1 receptor for therapeutic neovascularization.
Emanueli, C., Salis, M.B., Stacca, T., Pintus, G., Kirchmair, R., Isner, J.M., Pinna, A., Gaspa, L., Regoli, D., Cayla, C., Pesquero, J.B., Bader, M. and Madeddu, P.
Circulation 105 : 360-366. 22 January 2002

Circulation Research

Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.
Schleifenbaum, J., Kassmann, M., Szijártó, I.A., Hercule, H.C., Tano, J.Y., Weinert, S., Heidenreich, M., Pathan, A.R., Anistan, Y.M., Alenina, N., Rusch, N.J., Bader, M., Jentsch, T.J. and Gollasch, M.
Circulation Research 115 (2): 263-272. 7 July 2014

Discovery and characterization of alamandine, a novel component of the renin-angiotensin system.
Lautner, R.Q., Villela, D.C., Fraga-Silva, R.A., Silva, N.C., Verano-Braga, T., Costa-Fraga, F., Jankowski, J., Jankowski, V., De Sousa, F.B., Alzamora, A.C., Soares, E.R., Barbosa, C.M., Kjeldsen, F., Oliveira, A.C., Braga, J.F., Savergnini, S.Q., Etelvino, G.M., Bastos Peluso, A.A., Passos-Silva, D.G., Ferreira, A.J., Alves, F., Martins, A.S., Raizada, M.K., Paula, R.D., Motta-Santos, D., Klempin, F., Pimenta, A.M.C., Alenina, N., Sinisterra, R.D.M., Bader, M., Campagnole-Santos, M.J. and Santos, R.A.S.
Circulation Research 112 (8): 1104-1111. 12 April 2013

Arteriogenesis is modulated on bradykinin receptor signaling.
Hillmeister, P., Gatzke, N., Duelsner, A., Bader, M., Schadock, I., Hoefer, I., Hamann, I., Infante-Duarte, C., Jung, G., Troidl, K., Urban, D., Stawowy, P., Frentsch, M., Li, M., Nagorka, S., Wang, H., Shi, Y., le Noble, F. and Buschmann, I.
Circulation Research 109 (5): 524-533. 19 August 2011

Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart.
Mercure, C., Yogi, A., Callera, G.E., Aranha, A.B., Bader, M., Ferreira, A.J., Santos, R.A., Walther, T., Touyz, R.M. and Reudelhuber, T.L.
Circulation Research 103 (11): 1319-1326. 21 November 2008

Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel.
Si, H., Heyken, W.T., Woelfle, S.E., Tysiac, M., Schubert, R., Grgic, I., Vilianovich, L., Giebing, G., Maier, T., Gross, V., Bader, M., de Wit, C., Hoyer, J. and Koehler, R.
Circulation Research 99 (5): 537-544. 1 September 2006

Bradykinin B1 receptor expression induced by tissue damage in the rat portal vein - A critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways.
Medeiros, R., Cabrini, D.A., Ferreira, J., Fernandes, E.S., Mori, M.A.S., Pesquero, J.B., Bader, M., Avellar, M.C.W., Campos, M.M. and Calixto, J.B.
Circulation Research 94 (10): 1375-1382. 1 January 2004

It's renin in the brain - Transgenic animals elucidate the brain renin-angiotensin system.
Bader, M. and Ganten, D.
Circulation Research 90 (1): 8-10. 1 January 2002

Impaired long-chain fatty acid utilization by cardiac myocytes isolated from mice lacking the heart-type fatty acid binding protein gene.
Schaap, F.G., Binas, B., Danneberg, H., van der Vusse, G.J. and Glatz, J.F.C.
Circulation Research 85 : 329-337. 20 August 1999

Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents.
Maltsev, V.A., Wobus, A.M., Rohwedel, J., Bader, M. and Hescheler, J.
Circulation Research 75 (2): 233-244. 1 August 1994

Clinical Science

G-protein-coupled receptor MAS DeLETION produces a preeclampsia-like phenotype in FVB/N mice.
Vieira Pimentel, R.L., Braga, J.F., Velloso, E.P.P., Lautner, R.Q., Oliveira, M.L., Todiras, M., Alenina, N., Bader, M., de Sousa, F.G., Beier, S.L. and Souza Dos Santos, R.A.
Clinical Science 137 (16): 1249-1263. August 2023

Hemodynamic phenotyping of transgenic rats with ubiquitous expression of an angiotensin-(1-7)-producing fusion protein.
Alves, D.T., Mendes, L.F., Sampaio, W.O., Coimbra-Campos, L.M.C., Vieira, M.A.R., Ferreira, A.J., Martins, A.S., Popova, E., Todiras, M., Qadri, F., Alenina, N., Bader, M., Santos, R.A.S. and Campagnole-Santos, M.J.
Clinical Science 135 (18): 2197-2216. 8 September 2021

Increased angiotensin II formation in the brain modulates cardiovascular homeostasis and erythropoiesis.
Rodrigues, A.F., Todiras, M., Qadri, F., Campagnole-Santos, M.J., Alenina, N. and Bader, M.
Clinical Science 135 (11): 1353-1367. 2 June 2021

ACE2, a multifunctional protein - from cardiovascular regulation to COVID-19.
Bader, M., Turner, A.J. and Alenina, N.
Clinical Science 134 (23): 3229-3232. 11 December 2020

Identification of protein phosphatase involvement in the AT(2)-receptor induced activation of endothelial nitric oxide synthase.
Peluso, A.A., Bertelsen, J.B., Andersen, K., Mortensen, T.P., Hansen, P.B., Sumners, C., Bader, M., Santos, R.A. and Steckelings, U.M.
Clinical Science 132 (7): 777-790. 6 April 2018

Angiotensin type 2 receptor (AT2R) and receptor Mas: a complex liaison.
Villela, D., Leonhardt, J., Patel, N., Joseph, J., Kirsch, S., Hallberg, A., Unger, T., Bader, M., Santos, R.A., Sumners, C. and Steckelings, U.M.
Clinical Science 128 (4): 227-234. 1 February 2015

(Pro)renin receptor and V-ATPase: from Drosophila to humans.
Rousselle, A., Sihn, G., Rotteveel, M. and Bader, M.
Clinical Science 126 (8): 529-536. 1 April 2014

Renovascular hypertension with low-to-normal plasma renin: clinical and angiographic features.
Rossi, G.P., Pavan, E., Chiesura-Corona, M., Bader, M., Paganini, G., Cesari, M., De Toni, R., Feltrin, G.P., Ganten, D. and Pessina, A.C.
Clinical Science 93 : 435-443. 1 January 1997

Clinical and Experimental Pharmacology and Physiology

Transgenic rats: tools to study the function of the renin-angiotensin system. Proceedings of the symposium 'angiotensin AT1 receptors: from molecular physiology to therapeutics'.
Bader, M. and Ganten, D.
Clinical and Experimental Pharmacology and Physiology Suppl.3 : S81-S87. 1 January 1996

Clinics

An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect.
Fraga-Silva, R.A., Costa-Fraga, F.P., Sousa, F.B., Alenina, N., Bader, M., Sinisterra, R.D. and Santos, R.A.
Clinics 66 (5): 837-841. 2011

Computers in Cardiology

Complex narrow band-pass filters for QRS detection in contactless magnetocardiograms of small animals.
Steinhoff, U., Link, A., Wiekhorst, F., Bader, M., Knappe-Grueneberg, S. and Ackermann, R.
Computers in Cardiology 32 : 467-470. 2005

Current Opinion in Nephrology and Hypertension

Genetically altered animals in the study of the metabolic functions of peptide hormone systems.
Alves-da-Silva Mori, M., Bader, M. and Pesquero, J.B.
Current Opinion in Nephrology and Hypertension 17 (1): 11-17. January 2008

Cytogenetics and Cell Genetics

Assignment of the kinin receptor B1 and B2 genes (Bdkrb1 and Bdkrb2) to rat chromosome 6q3.2 by FISH and radiation hybrid mapping.
Goesele, C., Gruetzner, F., Pesquero, J.B., Silva, J.A., Junge, T., Ganten, D., Bader, M. and Knoblauch, M.
Cytogenetics and Cell Genetics 89 (1-2): 51-52. 1 January 2000

Development

Kpna6 deficiency causes infertility in male mice by disrupting spermatogenesis.
Liu, N., Qadri, F., Busch, H., Huegel, S., Sihn, G., Chuykin, I., Hartmann, E., Bader, M. and Rother, F.
Development 148 (19): dev.198374. 1 October 2021

A Grhl2-dependent gene network controls trophoblast branching morphogenesis.
Walentin, K., Hinze, C., Werth, M., Haase, N., Varma, S., Morell, R., Aue, A., Pötschke, E., Warburton, D., Qiu, A., Barasch, J., Purfürst, B., Dieterich, C., Popova, E., Bader, M., Dechend, R., Staff, A.C., Yurtdas, Z.Y., Kilic, E. and Schmidt-Ott, K.M.
Development 142 (6): 1125-1136. 15 March 2015

Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models.
Cristofaro, B., Shi, Y., Faria, M., Suchting, S., Leroyer, A.S., Trindade, A., Duarte, A., Zovein, A.C., Iruela-Arispe, M.L., Nih, L.R., Kubis, N., Henrion, D., Loufrani, L., Todiras, M., Schleifenbaum, J., Gollasch, M., Zhuang, Z.W., Simons, M., Eichmann, A. and le Noble, F.
Development 140 (8): 1720-1729. April 2013

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex.
Werth, M., Walentin, K., Aue, A., Schoenheit, J., Wuebken, A., Pode-Shakked, N., Vilianovitch, L., Erdmann, B., Dekel, B., Bader, M., Barasch, J., Rosenbauer, F., Luft, F.C. and Schmidt-Ott, K.M.
Development 137 (22): 3835-3845. November 2010

Developmental Cell

Serotonin regulates mammary gland development via an autocrine-paracrine loop.
Matsuda, M., Imaoka, T., Vomachka, A.J., Gudelsky, G.A., Hou, Z.Y., Mistry, M., Bailey, J.P., Nieport, K.M., Walther, D.J., Bader, M. and Horseman, N.D.
Developmental Cell 6 (2): 193-203. 1 January 2004

Diabetes

Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy.
Westermann, D., Walther, T., Savvatis, K., Sobirey, M., Riad, A., Bader, M., Schultheiss, H.P. and Tschoepe, C.
Diabetes 58 (6): 1373-1381. June 2009

Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity.
Mori, M.A., Araújo, R.C., Reis, F.C., Sgai, D.G., Fonseca, R.G., Barros, C.C., Merino, V.F., Passadore, M., Barbosa, A.M., Ferrari, B., Carayon, P., Castro, C.H., Shimuta, S.I., Luz, J., Bascands, J.L., Schanstra, J.P., Even, P.C., Oliveira, S.M., Bader, M. and Pesquero, J.B.
Diabetes 57 (6): 1491-1500. June 2008

Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolism.
Santos, S.H.S., Fernandes, L.R., Mario, E.G., Ferreira, A.V., Porto, L.C., Alvarez-Leite, J.I., Botion, L.M., Bader, M., Alenina, N. and Santos, R.A.
Diabetes 57 (2): 340-347. 1 February 2008

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

Kinin B1 and B2 receptor deficiency protects against obesity induced by a high-fat diet and improves glucose tolerance in mice.
Morais, R.L., Silva, E.D., Sales, V.M., Filippelli-Silva, R., Mori, M.A., Bader, M. and Pesquero, J.B.
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 8 : 399-407. 26 August 2015

Diabetologia

Diabetic pregnancy as a novel risk factor for cardiac dysfunction in the offspring-the heart as a target for fetal programming in rats.
Schütte, T., Kedziora, S.M., Haase, N., Herse, F., Alenina, N., Müller, D.N., Bader, M., Schupp, M., Dechend, R., Golic, M. and Kräker, K.
Diabetologia 64 (12): 2829-2842. December 2021

The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown.
Reichhart, N., Crespo-Garcia, S., Haase, N., Golic, M., Skosyrski, S., Rübsam, A., Herrspiegel, C., Kociok, N., Alenina, N., Bader, M., Dechend, R., Strauss, O. and Joussen, A.M.
Diabetologia 60 (1): 202-211. January 2017

Digestive Diseases and Sciences

Mast cells and serotonin synthesis modulate Chagas disease in the colon: clinical and experimental evidence.
Kannen, V., Sakita, J.Y., Carneiro, Z.A., Bader, M., Alenina, N., Teixeira, R.R., de Oliveira, E.C., Brunaldi, M.O., Gasparotto, B., Sartori, D.C., Fernandes, C.R., Silva, J.S., Andrade, M.V., Silva, W.A., Uyemura, S.A. and Garcia, S.B.
Digestive Diseases and Sciences 63 (6): 1473-1484. June 2018

Disease Models & Mechanisms

Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas.
Morales, M.G., Abrigo, J., Acuna, M.J., Santos, R.A., Bader, M., Brandan, E., Simonetta, F., Olguin, H., Cabrera, D. and Cabello-Verrugio, C.
Disease Models & Mechanisms 9 (4): 441-449. 1 April 2016

Doklady Biological Sciences

The possibilities of optical laser technologies in cell engineering.
Shakhbazyan, A.K., Karmenyan, A.K., Sviridova-Chailakhyan, T.A., Krivokharchenko, A.S., Chiou, A. and Chailakhyan, L.M.
Doklady Biological Sciences 429 (1): 587-590. December 2009

The use of laser for obtaining recipient cytoplasts for mammalian nuclear transfer.
Shakhbazyan, A.K., Sviridova-Chailakhyan, T.A., Karmenyan, A.K., Krivokharchenko, A.S., Chiou, A. and Chailakhyan, L.M.
Doklady Biological Sciences 428 : 475-478. October 2009

EMBO Journal

Axonal transcription factors signal retrogradely in lesioned peripheral nerve.
Ben-Yaakov, K., Dagan, S.Y., Segal-Ruder, Y., Shalem, O., Vuppalanchi, D., Willis, D.E., Yudin, D., Rishal, I., Rother, F., Bader, M., Blesch, A., Pilpel, Y., Twiss, J.L. and Fainzilber, M.
EMBO Journal 31 (6): 1350-1363. 13 January 2012

EMBO Molecular Medicine

The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment.
Schloss, M.J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O. and Steffens, S.
EMBO Molecular Medicine 8 (8): 937-948. 1 August 2016

EMBO Reports

Stem-cell research: the state of the art. Future regulations of embryonic-stem-cell research will be influenced more by economic interests and cultural history than by ethical concerns.
Pompe, S., Bader, M. and Tannert, C.
EMBO Reports 6 (4): 297-300. 1 January 2005

Encyclopedia of Molecular Pharmacology

Renin-angiotensin-aldosterone system.
Bader, M.
In: Encyclopedia of Molecular Pharmacology : Third Edition. Springer, Cham, 1353-1358. ISBN 978-3-030-57400-0 2021

Encyclopedia of Stress

Angiotensin.
Baltatu, O. and Bader, M.
In: Encyclopedia of Stress. UNSPECIFIED, 182-186. ISBN 978-0-12-373947-6 2007

Endocrine Connections

Glucagon-producing cells are increased in Mas-deficient mice.
Felix Braga, J., Ravizzoni Dartora, D., Alenina, N., Bader, M. and Santos, R.A.S.
Endocrine Connections 6 (1): 27-32. January 2017

Endocrinology

The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.
Sander, M., Bader, M., Djavidani, B., Masergluth, C., Vecsei, P., Mullins, J.J., Ganten, D. and Peters, J.
Endocrinology 131 (2): 807-814. 1 August 1992

European Archives of Psychiatry and Clinical Neuroscience

Laying out the evidence for the persistence of neurogenesis in the adult human hippocampus.
Kronenberg, G. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 270 (4): 497-498. June 2020

Brain serotonin critically contributes to the biological effects of electroconvulsive seizures.
Kronenberg, G., Petermann, M., Dormann, C., Bader, M., Gass, P., Hellweg, R. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 268 (8): 861-864. December 2018

Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin.
Kronenberg, G., Mosienko, V., Gertz, K., Alenina, N., Hellweg, R. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 266 (3): 281-284. April 2016

European Journal of Neuroscience

Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat.
Hansson, A.C., Cintra, A., Belluardo, N., Sommer, W., Bhatnagar, M., Bader, M., Ganten, D. and Fuxe, K.
European Journal of Neuroscience 12 (8): 2918-2934. 1 August 2000

European Journal of Pharmacology

Role of kinin receptors in skin pigmentation.
Ferreira, J.C.P., Soley, B.S., Pawloski, P.L., Moreira, C.G., Pesquero, J.B., Bader, M., Calixto, J.B., Cabrini, D.A. and Otuki, M.F.
European Journal of Pharmacology 973 : 176537. 15 June 2024

Antinociceptive response in transgenic mice expressing rat tonin.
da Fonseca Pacheco, D., da Fonseca Pacheco, C.M., de Paula Lima, M., Bader, M., de Lima Souza, A., Pesquero, J.L., Castro Perez, A. and Duarte, I.D.G.
European Journal of Pharmacology 713 (1-3): 1-5. 5 August 2013

Effects of angiotensin II and IV on geniculate activity in nontransgenic and transgenic rats.
Albrecht, D., Broser, M., Krueger, H. and Bader, M.
European Journal of Pharmacology 332 : 53-63. 1 January 1997

European Journal of Pharmacology - Molecular Pharmacology Section

Cardiac function and remodeling is attenuated in transgenic rats expressing the human kallikrein-1 gene after myocardial infarction.
Koch, M., Spillmann, F., Dendorfer, A., Westermann, D., Altmann, C., Sahabi, M., van Linthout, S., Bader, M., Walther, T., Schultheiss, H.P. and Tschoepe, C.
European Journal of Pharmacology - Molecular Pharmacology Section 550 (1-3): 143-148. 21 November 2006

Experimental Nephrology

Focal overexpression of collagen IV characterizes the initiation of epithelial changes in polycystic kidney disease.
Schaefer, K., Bader, M., Gretz, N., Oberbaeumer, I. and Bachmann, S.
Experimental Nephrology 2 : 190-195. 1 January 1994

Experimental Neurology

Distinct roles of angiotensin receptors in autonomic dysreflexia following high-level spinal cord injury in mice.
Järve, A., Todiras, M., Lian, X, Filippelli-Silva, R., Qadri, F., Martin, R.P., Gollasch, M. and Bader, M.
Experimental Neurology 311 : 173-181. January 2019

Experimental Physiology

Angiotensin‐II receptor type Ia does not contribute to cardiac atrophy following high‐thoracic spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S. and Bader, M.
Experimental Physiology 105 (8): 1316-1325. 1 August 2020

AVE 0991, a non-peptide Mas-receptor agonist, facilitates penile erection.
da Costa-Goncalves, A.C., Fraga-Silva, R.A., Leite, R. and Santos, R.A.S.
Experimental Physiology 98 (3): 850-855. March 2013

The kinin B1 receptor contributes to the cardioprotective effect of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in mice.
Xu, J., Carretero, O.A., Shesely, E.G., Rhaleb, N.E., Yang, J.J., Bader, M. and Yang, X.P.
Experimental Physiology 94 (3): 322-329. March 2009

Genetically altered animal models for Mas and Angiotensin-(1-7).
Alenina, N., Xu, P., Rentzsch, B., Patkin, E.L. and Bader, M.
Experimental Physiology 93 (5): 528-537. May 2008

Transgenic animals in cardiovascular disease research.
Bader, M., Bohnemeier, H., Zollmann, F.S., Lockley-Jones, O.E. and Ganten, D.
Experimental Physiology 85 (6): 713-731. 1 November 2000

Expert Opinion on Emerging Drugs

Emerging drugs which target the renin-angiotensin-aldosterone system.
Steckelings, U.M., Paulis, L., Unger, T. and Bader, M.
Expert Opinion on Emerging Drugs 16 (4): 619-630. December 2011

Expert Opinion on Therapeutic Patents

Therapeutic targeting of the angiotensin-converting enzyme 2/Angiotensin-(1-7)/Mas cascade in the renin-angiotensin system: a patent review.
Ferreira, A.J., Bader, M. and Santos, R.A.S.
Expert Opinion on Therapeutic Patents 22 (5): 567-574. May 2012

Expert Opinion on Therapeutic Targets

Kinin B1 receptors as a therapeutic target for inflammation.
Qadri, F. and Bader, M.
Expert Opinion on Therapeutic Targets 22 (1): 31-44. January 2018

Exploration of Medicine

Placental CD4(+) T cells from preeclamptic patients cause autoantibodies to the angiotensin II type I receptor and hypertension in a pregnant rat model of preeclampsia.
Reeve, K.E., Deer, E., Amaral, L.M., Cornelius, D.C., Herrock, O., Harmon, A.C., Campbell, N., Fitzgerald, S., Ibrahim, T., Wallukat, G., Dechend, R. and LaMarca, B.
Exploration of Medicine 3 : 99-111. 25 February 2022

FASEB Journal

Karyopherin α2 is a maternal effect gene required for early embryonic development and female fertility in mice.
Rother, F., Depping, R., Popova, E., Huegel, S., Heiler, A., Hartmann, E. and Bader, M.
FASEB Journal 38 (8): e23623. 30 April 2024

Phenylalanine-hydroxylase contributes to serotonin synthesis in mice.
Mordhorst, A., Dhandapani, P., Matthes, S., Mosienko, V., Rothe, M., Todiras, M., Self, J., Schunck, W.H., Schütz, A., Bader, M. and Alenina, N.
FASEB Journal 35 (6): e21648. June 2021

Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction.
Järve, A., Mühlstedt, S., Qadri, F., Nickl, B., Schulz, H., Hübner, N., Özcelik, C. and Bader, M.
FASEB Journal 31 (2): 556-568. February 2017

Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits.
Katter, K., Geurts, A.M., Hoffmann, O., Mátés, L., Landa, V., Hiripi, L., Moreno, C., Lazar, J., Bashir, S., Zidek, V., Popova, E., Jerchow, B., Becker, K., Devaraj, A., Walter, I., Grzybowksi, M., Corbett, M., Filho, A.R., Hodges, M.R., Bader, M., Ivics, Z., Jacob, H.J., Pravenec, M., Bosze, Z., Rülicke, T. and Izsvák, Z.
FASEB Journal 27 (3): 930-941. March 2013

Angioprotectin: an angiotensin II-like peptide causing vasodilatory effects.
Jankowski, V., Toelle, M., Santos, R.A., Guenthner, T., Krause, E., Beyermann, M., Welker, P., Bader, M., Pinheiro, S.V.B., Sampaio, W.O., Lautner, R., Kretschmer, A., van der Giet, M., Zidek, W. and Jankowski, J.
FASEB Journal 25 (9): 2987-2995. September 2011

Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy.
Klein, J., Gonzalez, J., Duchene, J., Esposito, L., Pradere, J.P., Neau, E., Delage, C., Calise, D., Ahluwalia, A., Carayon, P., Pesquero, J.B., Bader, M., Schanstra, J.P. and Bascands, J.L.
FASEB Journal 23 (1): 134-142. January 2009

Mice deficient for both kinin receptors are normotensive and protected from endotoxin- induced hypotension.
Cayla, C., Todiras, M., Iliescu, R., Saul, V.V., Gross, V., Pilz, B., Chai, G., Merino, V.F., Pesquero, J.B., Baltatu, O.C. and Bader, M.
FASEB Journal 21 (8): 1689-1698. June 2007

Central angiotensin II controls alcohol consumption via its AT1 receptor.
Maul, B., Krause, W., Pankow, K., Becker, M., Gembardt, F., Alenina, N., Walther, T., Bader, M. and Siems, W.E.
FASEB Journal 19 (11): 1474-1481. 1 September 2005

Transgenic activation of the kallikrein-kinin system inhibits intramyocardial inflammation, endothelial dysfunction, and oxidative stress in experimental diabetic cardiomyopathy.
Tschoepe, C., Walther, T., Escher, F., Spillmann, F., Du, J., Altmann, C., Schimke, I., Bader, M., Sanchez-Ferrer, C.F., Schultheiss, H.P. and Noutsias, M.
FASEB Journal 19 (14): 2057-2059. 29 August 2005

Improvement of defective sarcoplasmic reticulum Ca2+ transport in diabetic heart of transgenic rats expressing the human kallikrein-1 gene.
Tschoepe, C., Spillmann, F., Rehfeld, U., Koch, M., Westermann, D., Altmann, C., Dendorfer, A., Walther, T., Bader, M., Paul, M., Schultheiss, H.P. and Vetter, R.
FASEB Journal 18 (15): 1967-1969. 24 September 2004

Prevention of cardiac fibrosis and left ventricular dysfunction in diabetic cardiomyopathy in rats by transgenic expression of the human tissue kallikrein gene.
Tschoepe, C., Walther, T., Koeniger, J., Spillmann, F., Westermann, D., Escher, F., Pauschinger, M., Pesquero, J.B., Bader, M., Schultheiss, H.P. and Noutsias, M.
FASEB Journal 18 (7): 828-835. May 2004

Uncoupling protein 3 as a mitochondrial fatty acid anion exporter.
Schrauwen, P., Hoeks, J., Schaart, G., Kornips, E., Binas, B., van de Vusse, G.J., van Bilsen, M., Luiken, J.J.F.P., Coort, S.L.M., Glatz, J.F.C., Saris, W.H.M. and Hesselinkt, M.K.C.
FASEB Journal 17 (15): 2272-2274. December 2003

Trypanosoma cruzi induces edematogenic responses in mice and invades cardiomyocytes and endothelial cells in vitro by activating distinct kinin receptor subtypes (B-1/B-2).
Todorov, A.G., Andrade, D., Pesquero, J.B., de Carvalho Araujo, R., Bader, M., Stewart, J., Gera, L., Mueller-Esterl, W., Morandi, V., Goldenberg, R.C.S., Neto, H.C.F. and Scharfstein, J.
FASEB Journal 17 (1): U371-U392. January 2003

Ischemic injury in experimental stroke depends on angiotensin II.
Walther, T., Olah, L., Harms, C., Maul, B., Bader, M., Hoertnagl, H., Schultheiss, H.P. and Mies, G.
FASEB Journal 16 (2): 169-176. February 2002

Alcohol consumption is controlled by angiotensin II.
Maul, B., Siems, W.E., Hoehe, M.R., Grecksch, G., Bader, M. and Walther, T.
FASEB Journal 15 : 1640-1642. 1 July 2001

Increased kallikrein expression protects against cardiac ischemia.
Pinto, Y.M., Bader, M., Pesquero, J.B., Tschoepe, C., Scholtens, E., van Gilst, W.H. and Buikema, H.
FASEB Journal 14 (13): 1861-1863. 1 October 2000

Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene.
Silva, J.A., Araujo, R.C., Baltatu, O., Oliveira, S.M., Tschoepe, C., Fink, E., Hoffmann, S., Plehm, R., Chai, K.X., Chao, L., Chao, J., Ganten, D., Pesquero, J.B. and Bader, M.
FASEB Journal 14 (13): 1858-1860. 1 October 2000

Requirement for the heart-type fatty acid binding protein in cardiac fatty acid utilization.
Binas, B., Danneberg, H., McWhir, J., Mullins, L. and Clark, A.J.
FASEB Journal 13 (8): 805-812. May 1999

FEBS Letters

Expression of the mouse and rat mas proto-oncogene in the brain and peripheral tissues.
Metzger, R., Bader, M., Ludwig, T., Berberich, C., Bunnemann, B. and Ganten, D.
FEBS Letters 357 : 27-32. 1 January 1995

FEBS Open Bio

Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice.
Jansch, M., Lubomirov, L.T., Trum, M., Williams, T., Schmitt, J., Schuh, K., Qadri, F., Maier, L.S., Bader, M. and Ritter, O.
FEBS Open Bio 13 (1): 118-132. January 2023

Frontiers in Behavioral Neuroscience

Serotonin drives aggression and social behaviours of laboratory mice in a semi-natural environment.
Rivalan, M., Alonso, L., Mosienko, V., Bey, P., Hyde, A., Bader, M., Winter, Y. and Alenina, N.
Frontiers in Behavioral Neuroscience 18 18 September 2024

Frontiers in Bioscience

(Pro)renin receptor: subcellular localizations and functions.
Sihn, G., Burckle, C., Rousselle, A., Reimer, T. and Bader, M.
Frontiers in Bioscience 5 : 500-508. 1 January 2013

Frontiers in Cardiovascular Medicine

Angiotensin receptor-neprilysin inhibitor improves coronary collateral perfusion.
Li, K., Kratzmann, V., Dai, M., Gatzke, N., Rocic, P., Bramlage, P., Grisk, O., Lubomirov, L.T., Hoffmeister, M., Lauxmann, M.A., Ritter, O., Buschmann, E., Bader, M., Persson, A.B., Buschmann, I. and Hillmeister, P.
Frontiers in Cardiovascular Medicine 9 : 981333. 3 February 2023

(Pro)renin receptor inhibition reduces plasma cholesterol and triglycerides but does not attenuate atherosclerosis in atherosclerotic mice.
Ye, D., Yang, X., Ren, L., Lu, H.S., Sun, Y., Lin, H., Tan, L., Wang, N., Nguyen, G., Bader, M., Mullick, A.E., Danser, A.H.J., Daugherty, A., Jiang, Y., Sun, Y., Li, F. and Lu, X.
Frontiers in Cardiovascular Medicine 8 : 725203. 24 December 2021

Frontiers in Cell and Developmental Biology

Lack of brain serotonin affects feeding and differentiation of newborn cells in the adult hypothalamus.
van Lingen, M., Sidorova, M., Alenina, N. and Klempin, F.
Frontiers in Cell and Developmental Biology 7 : 65. April 2019

Frontiers in Cellular Neuroscience

The absence of serotonin in the brain alters acute stress responsiveness by interfering with the genomic function of the glucocorticoid receptors.
Sbrini, G., Brivio, P., Peeva, P.M., Todiras, M., Bader, M., Alenina, N. and Calabrese, F.
Frontiers in Cellular Neuroscience 14 : 128. 1 June 2020

Frontiers in Endocrinology

Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting.
Bolduan, F., Wetzel, A., Giesecke, Y., Eichhorn, I., Alenina, N., Bader, M., Willnow, T.E., Wiedenmann, B. and Sigal, M.
Frontiers in Endocrinology 15 : 1331231. 17 April 2024

Editorial: Sexual dimorphism in biomedical research and its therapeutic implications.
Kroon, J., Mahmoodzadeh, S. and Helsen, C.
Frontiers in Endocrinology 13 : 1009712. 19 August 2022

Continuous blood glucose monitoring reveals enormous circadian variations in pregnant diabetic rats.
Golic, M., Kräker, K., Fischer, C., Alenina, N., Haase, N., Herse, F., Schütte, T., Henrich, W., Müller, D.N., Busjahn, A., Bader, M. and Dechend, R.
Frontiers in Endocrinology 9 : 271. 29 May 2018

Frontiers in Immunology

Functional autoantibodies against G protein-coupled receptors in hepatic and pulmonary hypertensions in human schistosomiasis.
Botoni, F.A., Lambertucci, J.R., Santos, R.A.S., Müller, J., Talvani, A. and Wallukat, G.
Frontiers in Immunology 15 : 1404384. 17 June 2024

Functional antibodies against G-protein coupled receptors in Beagle dogs infected with two different strains of Trypanosoma cruzi.
Wallukat, G., Botoni, F.A., Rocha, M.O.C., Louise, V., Müller, J. and Talvani, A.
Frontiers in Immunology 13 : 926682. 25 October 2022

Agonistic β2-adrenergic receptor autoantibodies characterize the aqueous humor of patients with primary and secondary open-angle glaucoma.
Hohberger, B., Wörn, M., Lämmer, R., Mahajan, A., Mardin, C., Schötzer-Schrehardt, U., Kunze, R., Herrmann, M. and Wallukat, G.
Frontiers in Immunology 12 : 550236. 5 May 2021

Frontiers in Medicine

Chronic overexpression of bradykinin in kidney causes polyuria and cardiac hypertrophy.
Barros, C.C., Schadock, I., Sihn, G., Rother, F., Xu, P., Popova, E., Lapidus, I., Plehm, R., Heuser, A., Todiras, M., Bachmann, S., Alenina, N., Araujo, R.C., Pesquero, J.B. and Bader, M.
Frontiers in Medicine 5 : 338. December 2018

Frontiers in Molecular Biosciences

Angiotensin-converting enzyme inhibitor protects against cisplatin nephrotoxicity by modulating kinin B1 receptor expression and aminopeptidase P activity in mice.
Estrela, G.R., Wasinski, F., Gregnani, M.F., Freitas-Lima, L.C., Arruda, A.C., Morais, R.L., Malheiros, D.M.A.C., Camara, N.O.S., Pesquero, J.B., Bader, M., Barros, C.C. and Araújo, R.C.
Frontiers in Molecular Biosciences 7 : 96. 20 May 2020

Frontiers in Molecular Neuroscience

Serotonylation: serotonin signaling and epigenetics.
Bader, M.
Frontiers in Molecular Neuroscience 12 : 288. 21 November 2019

TPH2 deficiency influences neuroplastic mechanisms and alters the response to an acute stress in a sex specific manner.
Brivio, P., Sbrini, G., Peeva, P., Todiras, M., Bader, M., Alenina, N. and Calabrese, F.
Frontiers in Molecular Neuroscience 11 : 389. 30 October 2018

Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats.
Barmashenko, G., Buttgereit, J., Herring, N., Bader, M., Oezcelik, C., Manahan-Vaughan, D. and Braunewell, K.H.
Frontiers in Molecular Neuroscience 7 : 95. 1 December 2014

Frontiers in Neuroscience

Serotonin deficiency increases context-dependent fear learning through modulation of hippocampal activity.
Waider, J., Popp, S., Mlinar, B., Montalbano, A., Bonfiglio, F., Aboagye, B., Thuy, E., Kern, R., Thiel, C., Araragi, N., Svirin, E., Schmitt-Böhrer, A.G., Corradetti, R., Lowry, C.A. and Lesch, K.P.
Frontiers in Neuroscience 13 : 245. April 2019

Maternal forced swimming reduces cell proliferation in the postnatal dentate gyrus of mouse offspring.
Wasinski, F., Estrela, G.R., Arakaki, A.M., Bader, M., Alenina, N., Klempin, F. and Araújo, R.C.
Frontiers in Neuroscience 10 : 402. 29 August 2016

Frontiers in Pharmacology

Bradykinin B2 receptor signaling increases glucose uptake and oxidation: evidence and open questions.
Gregnani, M.F., Hungaro, T.G., Martins-Silva, L., Bader, M. and Araujo, R.C.
Frontiers in Pharmacology 11 : 1162. 4 August 2020

TRPM8 activation via 3-iodothyronamine blunts VEGF-induced transactivation of TRPV1 in human uveal melanoma cells.
Walcher, L., Budde, C., Böhm, A., Reinach, P.S., Dhandapani, P., Ljubojevic, N., Schweiger, M.W., von der Waydbrink, H., Reimers, I., Köhrle, J. and Mergler, S.
Frontiers in Pharmacology 9 : 1234. 13 November 2018

Frontiers in Physiology

Oxidative RNA damage in the pathogenesis and treatment of type 2 diabetes.
Chen, X., Yu, H., Li, Z., Ye, W., Liu, Z., Gao, J., Wang, Y., Li, X., Zhang, L., Alenina, N., Bader, M., Ding, H., Li, P. and Aung, L.H.H.
Frontiers in Physiology 13 : 725919. 28 March 2022

Angiotensin-(1-7) receptor Mas deficiency does not exacerbate cardiac atrophy following high-level spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S., Alenina, N. and Bader, M.
Frontiers in Physiology 11 : 203. 12 March 2020

Angiotensin-(1-7) receptor Mas in hemodynamic and thermoregulatory dysfunction after high-level spinal cord injury in mice: a pilot study.
Järve, A., Todiras, M., Kny, M., Fischer, F.I., Kraemer, J.F., Wessel, N., Plehm, R., Fielitz, J., Alenina, N. and Bader, M.
Frontiers in Physiology 9 : 1930. January 2019

Elastase-2, a tissue alternative pathway for angiotensin II generation, plays a role in circulatory sympathovagal balance in mice.
Becari, C., Durand, M.T., Guimaraes, A.O., Lataro, R.M., Prado, C.M., de Oliveira, M., Candido, S.C.O., Pais, P., Ribeiro, M.S., Bader, M., Pesquero, J.B., Salgado, M.C.O. and Salgado, H.C.
Frontiers in Physiology 8 : 170. 23 March 2017

Caloric restriction is more efficient than physical exercise to protect from cisplatin nephrotoxicity via PPAR-alpha activation.
Estrela, G.R., Wasinski, F., Batista, R.O., Hiyane, M.I., Felizardo, R.J.F., Cunha, F., de Almeida, D.C., Malheiros, D.M.A.C., Camara, N.O.S., Barros, C.C., Bader, M. and Araujo, R.C.
Frontiers in Physiology 8 : 116. 2 March 2017

Effect of angiotensin(1-7) on heart function in an experimental rat model of obesity.
Blanke, K., Schlegel, F., Raasch, W., Bader, M., Dähnert, I., Dhein, S. and Salameh, A.
Frontiers in Physiology 6 : 392. 21 December 2015

Brain renin-angiotensin system in hypertension, cardiac hypertrophy, and heart failure.
Campos, L.A., Bader, M. and Baltatu, O.C.
Frontiers in Physiology 2 : 115. 3 January 2012

Frontiers in Psychiatry

Overexpression of adenosine A2A receptors in rats: effects on depression, locomotion, and anxiety.
Coelho, J.E., Alves, P., Canas, P.M., Valadas, J.S., Shmidt, T., Batalha, V.L., Ferreira, D.G., Ribeiro, J.A., Bader, M., Cunha, R.A., do Couto, F.S. and Lopes, L.V.
Frontiers in Psychiatry 5 : 67. 13 June 2014

Fundamental & Clinical Pharmacology

Brain angiotensins in the cardiovascular regulation: usefulness of transgenic animals.
Bricca, G., Schinke, M., Boehm, M., Monti, J., Hof, H., Ganten, D. and Bader, M.
Fundamental & Clinical Pharmacology 11, Suppl.1 : 53s-57s. 1 January 1997

Inhibition of brain renin-angiotensin-system by triple-helix-forming oligonucleotides is associated with modulation of blood pressure power spectrum in rats.
Monti, J., Voss, A., Schinke, M., Boehm, M., Hoff, H., Bader, M., Ganten, D. and Bricca, G.
Fundamental & Clinical Pharmacology 11 Suppl. 1 : S116. 1 January 1997

Future Cardiology

Highlights of the 13th Annual Meeting of the European Council for Cardiovascular Research. 13th Annual Meeting of the European Council for Cardiovascular Research (ECCR). Nice, France, 10-12 October, 2008.
Bader, M.
Future Cardiology 5 (1): 23-25. January 2009

Gastroenterology

Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis.
Nocito, A., Dahm, F., Jochum, W., Jang, J.H., Georgiev, P., Bader, M., Renner, E.L. and Clavien, P.A.
Gastroenterology 133 (2): 608-618. August 2007

Geburtshilfe und Frauenheilkunde

Genexpression und Morphologie der Follikel nach konventionellem Einfrieren und Vitrifikation von humanem Ovarialgewebe [Gene-expression and morphology of follicles after conventional freezing and vitrification of human ovarian tissue].
Isachenko, V., Isachenko, E., Nawroth, F., Wiegratz, I., Kaufmann, M., Lapidus, I., Hancke, K. and Kreienberg, R.
Geburtshilfe und Frauenheilkunde 70 (7): 561-567. July 2010

Gene

Multiple non-coding exons and alternative splicing in the mouse Mas protooncogene.
Alenina, N., Böhme, I., Bader, M. and Walther, T.
Gene 568 (2): 155-164. 1 September 2015

Cloning and chromosomal localisation of the murine epidermal-type fatty acid binding protein gene (Fabpe).
Bleck, B., Hohoff, C., Binas, B., Ruestow, B., Dixkens, C., Hameister, H., Boerchers, T. and Spener, F.
Gene 215 : 123-130. 17 July 1998

Genes

Effect of culture conditions on viability of mouse and rat embryos developed in vitro.
Popova, E., Bader, M. and Krivokharchenko, A.
Genes 2 (2): 332-344. 1 April 2011

Gut

Expression and functional pharmacology of the bradykinin B1 receptor in the normal and inflamed human gallbladder.
Andre, E., Gazzieri, D., Bardella, E., Ferreira, J., Mori, M.A., Saul, V.V., Bader, M., Calixto, J.B., De Giorgio, R., Corinaldesi, R., Geppetti, P. and Trevisani, M.
Gut 57 (5): 628-633. May 2008

Handbook of Behavioral Neuroscience

The serotonin-free brain: behavioral consequences of Tph2 deficiency in animal models.
Mosienko, V., Bader, M. and Alenina, N.
In: Handbook of the Behavioral Neurobiology of Serotonin. Handbook of Behavioral Neuroscience, 31 . Elsevier, London et al., 601-607. ISBN 978-0-444-64125-0 2020

Heart and Vessels

Cardioprotective effect of thyroid hormone is mediated by AT2 receptor and involves nitric oxide production via Akt activation in mice.
da Silva, I.B., Gomes, D.A., Alenina, N., Bader, M., dos Santos, R.A. and Barreto-Chaves, M.L.M.
Heart and Vessels 33 (6): 671-681. June 2018

Heliyon

Carbon-mixed dental cement for fixing fiber optic ferrules prevents visually triggered locomotive enhancement in mice upon optogenetic stimulation.
Araragi, N., Alenina, N. and Bader, M.
Heliyon 8 (1): e08692. January 2022

Hepatology

Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice.
Nocito, A., Georgiev, P., Dahm, F., Jochum, W., Bader, M., Graf, R. and Clavien, P.A.
Hepatology 45 (2): 369-376. February 2007

Hippocampus

Priming of LTP in amygdala and hippocampus by prior paired pulse facilitation paradigm in mice lacking brain serotonin.
Gebhardt, C., Mosienko, V., Alenina, N. and Albrecht, D.
Hippocampus 29 (7): 610-618. July 2019

Hormones and Behavior

Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors.
Amado Costa, L., Oliveira Amaral, L.B., Mourão, F.A.G., Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Hormones and Behavior 163 : 105551. 27 April 2024

Human Molecular Genetics

Restoration of muscle strength in dystrophic muscle by Angiotensin-1-7 through inhibition of TGF-β signaling.
Acuna, M.J., Pessina, P., Olguin, H., Cabrera, D., Vio, C.P., Bader, M., Munoz-Canoves, P., Santos, R.A., Cabello-Verrugio, C. and Brandan, E.
Human Molecular Genetics 23 (5): 1237-1249. 1 March 2014

Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying Acromesomelic Dysplasia type Maroteaux.
Hume, A.N., Buttgereit, J., Al-Awadhi, A.M., Al-Suwaidi, S.S., John, A., Bader, M., Seabra, M.C., Al-Gazali, L. and Ali, B.R.
Human Molecular Genetics 18 (2): 267-277. 15 January 2009

Transgenic rat model of Huntington's disease.
von Hoersten, S., Schmitt, I., Nguyen, H.P., Holzmann, C., Schmidt, T., Walther, T., Bader, M., Pabst, R., Kobbe, P., Krotova, J., Stiller, D., Kask, A., Vaarmann, A., Rathke-Hartlieb, S., Schulz, J.B., Grasshoff, U., Bauer, I., Vieira-Saecker, A.M.M., Paul, M., Jones, L., Lindenberg, K.S., Landwehrmeyer, B., Bauer, A., Li, X.J. and Riess, O.
Human Molecular Genetics 12 (6): 617-624. 15 March 2003

Human Mutation

Overexpression of the C-type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation.
Bocciardi, R., Giorda, R., Buttgereit, J., Gimelli, S., Divizia, M.T., Beri, S., Garofalo, S., Tavella, S., Lerone, M., Zuffardi, O., Bader, M., Ravazzolo, R. and Gimelli, G.
Human Mutation 28 (7): 724-731. July 2007

Human Reproduction

Effects of electric field on early preimplantation development in vitro in mice and rats.
Popova, E., Bader, M. and Krivokharchenko, A.
Human Reproduction 26 (3): 662-670. March 2011

Hypertension

Angiotensin-(1-12): does it exist? A critical evaluation in humans, rats, and mice.
Rodrigues, A.F., Domenig, O., Poglitsch, M., Bader, M. and Danser, A.H.J.
Hypertension 81 (8): 1776-1784. August 2024

Alternative renin-angiotensin system.
Bader, M., Muscha Steckelings, U., Alenina, N., Santos, R.A.S. and Ferrario, C.M.
Hypertension 81 (5): 964-976. May 2024

Tail-cuff versus radiotelemetry to measure blood pressure in mice and rats.
Harrison, D.G., Bader, M., Lerman, L.O., Fink, G., Karumanchi, S.A., Reckelhoff, J.F., Sequeira-Lopez, M.L.S. and Touyz, R.M.
Hypertension 81 (1): 3-5. January 2024

Studies in zebrafish and rat models support dual blockade of EP2 and EP4 (prostaglandin E(2) receptors type 2 and 4) for renoprotection in glomerular hyperfiltration and albuminuria.
Kourpa, A., Schulz, A., Mangelsen, E., Kaiser-Graf, D., Koppers, N., Stoll, M., Rothe, M., Bader, M., Purfürst, B., Kunz, S., Gladytz, T., Niendorf, T., Bachmann, S., Mutig, K., Bolbrinker, J., Panakova, D. and Kreutz, R.
Hypertension 80 (4): 771-782. April 2023

Quantitative phosphoproteomics of the angiotensin AT(2)-receptor signaling network identifies HDAC1 (Histone-Deacetylase-1) and p53 as mediators of antiproliferation and apoptosis.
Peluso, A.A.B., Kempf, S.J., Verano-Braga, T., Rodrigues-Ribeiro, L., Johansen, L.E., Hansen, M.R., Kitlen, G., Haugaard, A.H., Sumners, C., Ditzel, H.J., Santos, R.A., Bader, M., Larsen, M.R. and Steckelings, U.M.
Hypertension 79 (11): 2530-2541. November 2022

Intrauterine exposure to diabetic milieu does not induce diabetes and obesity in male adulthood in a novel rat model.
Schütte, T., Kedziora, S.M., Haase, N., Herse, F., Busjahn, A., Birukov, A., Alenina, N., Müller, D.N., Bader, M., Schupp, M., Dechend, R., Kräker, K. and Golic, M.
Hypertension 77 (1): 202-215. January 2021

Ang II (angiotensin II) conversion to angiotensin-(1-7) in the circulation is POP (prolyloligopeptidase)-dependent and ACE2 (angiotensin-converting enzyme 2)-independent.
Serfozo, P., Wysocki, J., Gulua, G., Schulze, A., Ye, M., Liu, P., Jin, J., Bader, M., Myöhänen, T., García-Horsman, J.A. and Batlle, D.
Hypertension 75 (1): 173-182. January 2020

Urinary renin in patients and mice with diabetic kidney disease.
Tang, J., Wysocki, J., Ye, M., Vallés, P.G., Rein, J., Shirazi, M., Bader, M., Gomez, R.A., Sequeira-Lopez, M.L.S., Afkarian, M. and Batlle, D.
Hypertension 74 (1): 83-94. July 2019

The Meaning of Mas.
Bader, M., Alenina, N., Young, D., Santos, R.A.S. and Touyz, R.M.
Hypertension 72 (5): 1072-1075. November 2018

Renin-angiotensin system in aortic aneurysm: still adding puzzle stones to an anything but complete picture.
Steckelings, U.M. and Bader, M.
Hypertension 72 (3): 579-581. September 2018

Cystathionine γ-lyase-produced hydrogen sulfide controls endothelial NO bioavailability and blood pressure.
Szijártó, I.A., Markó, L., Filipovic, M.R., Miljkovic, J.L., Tabeling, C., Tsvetkov, D., Wang, N., Rabelo, L.A., Witzenrath, M., Diedrich, A., Tank, J., Akahoshi, N., Kamata, S., Ishii, I. and Gollasch, M.
Hypertension 71 (6): 1210-1217. June 2018

Diabetes mellitus in pregnancy leads to growth restriction and epigenetic modification of the Srebf2 gene in rat fetuses.
Golic, M., Stojanovska, V., Bendix, I., Wehner, A., Herse, F., Haase, N., Kräker, K., Fischer, C., Alenina, N., Bader, M., Schütte, T., Schuchardt, M., van der Giet, M., Henrich, W., Muller, D.N., Felderhoff-Müser, U., Scherjon, S., Plösch, T. and Dechend, R.
Hypertension 71 (5): 911-920. May 2018

Of mice and renin.
Bader, M.
Hypertension 70 (1): 35-37. July 2017

Brain renin-angiotensin system: does it exist?
van Thiel, B.S., Góes Martini, A., Te Riet, L., Severs, D., Uijl, E., Garrelds, I.M., Leijten, F.P.J., van der Pluijm, I., Essers, J., Qadri, F., Alenina, N., Bader, M., Paulis, L., Rajkovicova, R., Domenig, O., Poglitsch, M. and Danser, A.H.J.
Hypertension 69 (6): 1136-1144. June 2017

Evidence for heterodimerization and functional interaction of the angiotensin Type 2 receptor and the receptor MAS.
Leonhardt, J., Villela, D.C., Teichmann, A., Münter, L.-M., Mayer, M.C., Mardahl, M., Kirsch, S., Namsolleck, P., Lucht, K., Benz, V., Alenina, N., Daniell, N., Horiuchi, M., Iwai, M., Multhaup, G., Schülein, R., Bader, M., Santos, R.A., Unger, T. and Steckelings, U.M.
Hypertension 69 (6): 1128-1135. June 2017

Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.
Markó, L., Henke, N., Park, J.K., Spallek, B., Qadri, F., Balogh, A., Apel, I.J., Oravecz-Wilson, K.I., Choi, M., Przybyl, L., Binger, K.J., Haase, N., Wilck, N., Heuser, A., Fokuhl, V., Ruland, J., Lucas, P.C., McAllister-Lucas, L.M., Luft, F.C., Dechend, R. and Müller, D.N.
Hypertension 64 (5): 1032-1039. November 2014

Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis.
Pulgar, V.M., Yamaleyeva, L.M., Varagic, J., McGee, C.M., Bader, M., Dechend, R., Howlett, A.C. and Brosnihan, K.B.
Hypertension 64 (3): 619-625. September 2014

Angiotensin 1-7 reduces mortality and rupture of intracranial aneurysms in mice.
Pena Silva, R.A., Kung, D.K., Mitchell, I.J., Alenina, N., Bader, M., Santos, R.A.S., Faraci, F.M., Heistad, D.D. and Hasan, D.M.
Hypertension 64 (2): 362-368. August 2014

Functional cross-talk between aldosterone and angiotensin-(1-7) in ventricular myocytes.
Machado de Almeida, P.W., de Freitas Lima, R., de Morais Gomes, E.R., Rocha-Resende, C., Roman-Campos, D., Gondim, A.N.S., Gavioli, M., Lara, A., Parreira, A., de Azevedo Nunes, S.L., Alves, M.N.M., Lauton Santos, S., Alenina, N., Bader, M., Ribeiro Resende, R., dos Santos Cruz, J., Souza dos Santos, R.A. and Guatimosim, S.
Hypertension 61 (2): 425-430. February 2013

Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling.
Guimaraes, P.B., Alvarenga, E.C., Siqueira, P.D., Paredes-Gamero, E.J., Sabatini, R.A., Morais, R.L., Reis, R.I., Santos, E.L., Teixeira, L.G., Casarini, D.E., Martin, R.P., Shimuta, S.I., Carmona, A.K., Nakaie, C.R., Jasiulionis, M.G., Ferreira, A.T., Pesquero, J.L., Oliveira, S.M., Bader, M., Costa-Neto, C.M. and Pesquero, J.B.
Hypertension 57 (5): 965-972. May 2011

Vascular relaxation, antihypertensive effect, and cardioprotection of a novel peptide agonist of the Mas receptor.
Savergnini, S.Q., Beiman, M., Lautner, R.Q., de Paula-Carvalho, V., Allahdadi, K., Pessoa, D.C., Costa-Fraga, F.P., Fraga-Silva, R.A., Cojocaru, G., Cohen, Y., Bader, M., de Almeida, A.P., Rotman, G. and Santos, R.A.
Hypertension 56 (1): 112-120. July 2010

Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor κB.
Rompe, F., Artuc, M., Hallberg, A., Alterman, M., Stroeder, K., Thoene-Reineke, C., Reichenbach, A., Schacherl, J., Dahloef, B., Bader, M., Alenina, N., Schwaninger, M., Zuberbier, T., Funke-Kaiser, H., Schmidt, C., Schunck, W.H., Unger, T. and Steckelings, U.M.
Hypertension 55 (4): 924-931. April 2010

Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3',5'-cyclic monophosphate-dependent pathway.
Gomes, E.R., Lara, A.A., Almeida, P.W., Guimaraes, D., Resende, R.R., Campagnole-Santos, M.J., Bader, M., Santos, R.A. and Guatimosim, S.
Hypertension 55 (1): 153-160. January 2010

Growth arrest specific protein 6 participates in DOCA-induced target-organ damage.
Park, J.K., Theuer, S., Kirsch, T., Lindschau, C., Klinge, U., Heuser, A., Plehm, R., Todiras, M., Carmeliet, P., Haller, H., Luft, F.C., Mueller, D.N. and Fiebeler, A.
Hypertension 54 (2): 359-364. August 2009

Energy metabolism in human renin-gene transgenic rats. Does renin contribute to obesity?
Gratze, P., Boschmann, M., Dechend, R., Qadri, F., Malchow, J., Graeske, S., Engeli, S., Janke, J., Springer, J., Contrepas, A., Plehm, R., Klaus, S., Nguyen, G., Luft, F.C. and Mueller, D.N.
Hypertension 53 (3): 516-523. March 2009

Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunction.
da Costa Goncalves, A.C., Tank, J., Diedrich, A., Hilzendeger, A., Plehm, R., Bader, M., Luft, F.C., Jordan, J. and Gross, V.
Hypertension 53 (2): 387-392. February 2009

Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.
Rentzsch, B., Todiras, M., Iliescu, R., Popova, E., Campos, L.A., Oliveira, M.L., Baltatu, O.C., Santos, R.A. and Bader, M.
Hypertension 52 (5): 967-973. November 2008

Role of the multidomain protein spinophilin in blood pressure and cardiac function regulation.
da Costa-Goncalves, A.C., Tank, J., Plehm, R., Diedrich, A., Todiras, M., Gollasch, M., Heuser, A., Wellner, M., Bader, M., Jordan, J., Luft, F.C. and Gross, V.
Hypertension 52 (4): 702-707. October 2008

Molecular mechanisms involved in the angiotensin-(1-7)/Mas signaling pathway in cardiomyocytes.
Dias-Peixoto, M.F., Santos, R.A., Gomes, E.R., Alves, M.N., Almeida, P.W., Greco, L., Rosa, M., Fauler, B., Bader, M., Alenina, N. and Guatimosim, S.
Hypertension 52 (3): 542-548. September 2008

Angiotensin-converting enzyme inhibition after experimental myocardial infarct: Role of the kinin B1 and B2 receptors.
Duka, A., Kintsurashvili, E., Duka, I., Ona, D., Hopkins, T.A., Bader, M., Gavras, I. and Gavras, H.
Hypertension 51 (5): 1352-1357. May 2008

Deficiency of bradykinin receptor B2 is not detrimental in experimental stroke.
Kleinschnitz, C., Austinat, M., Bader, M., Renne, T. and Stoll, G.
Hypertension 51 (5): e41. May 2008

ACE activity is modulated by kinin B2 receptor.
Sabatini, R.A., Guimaraes, P.B., Fernandes, L., Reis, F.C., Bersanetti, P.A., Mori, M.A., Navarro, A., Hilzendeger, A.M., Santos, E.L., Andrade, M.C., Chagas, J.R., Pesquero, J.L., Casarini, D.E., Bader, M., Carmona, A.K. and Pesquero, J.B.
Hypertension 51 (3): 689-695. March 2008

Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide.
Feldt, S., Batenburg, W.W., Mazak, I., Maschke, U., Wellner, M., Kvakan, H., Dechend, R., Fiebeler, A., Burckle, C., Contrepas, A., Danser, A.H., Bader, M., Nguyen, G., Luft, F.C. and Mueller, D.N.
Hypertension 51 (3): 682-688. March 2008

Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension.
Fischer, R., Dechend, R., Qadri, F., Markovic, M., Feldt, S., Herse, F., Park, J.K., Gapelyuk, A., Schwarz, I., Zacharzowsky, U.B., Plehm, R., Safak, E., Heuser, A., Schirdewan, A., Luft, F.C., Schunck, W.H. and Mueller, D.N.
Hypertension 51 (2): 540-546. February 2008

Endothelial dysfunction and elevated blood pressure in MAS gene-deleted mice.
Xu, P., Costa-Goncalves, A.C., Todiras, M., Rabelo, L.A., Sampaio, W.O., Moura, M.M., Santos, S.S., Luft, F.C., Bader, M., Gross, V., Alenina, N. and Santos, R.A.S.
Hypertension 51 (2): 574-580. February 2008

Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension.
Morecroft, I., Dempsie, Y., Bader, M., Walther, D.J., Kotnik, K., Loughlin, L., Nilsen, M. and Maclean, M.R.
Hypertension 49 (1): 232-236. January 2007

Prorenin and its ancient receptor.
Burckle, C. and Bader, M.
Hypertension 48 (4): 549-551. October 2006

Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor Mas knockout mice.
Santos, R.A., Castro, C.H., Gava, E., Pinheiro, S.V., Almeida, A.P., de Paula, R.D., Cruz, J.S., Ramos, A.S., Rosa, K.T., Irigoyen, M.C., Bader, M., Alenina, N., Kitten, G.T. and Ferreira, A.J.
Hypertension 547 (5): 996-1002. May 2006

Matrix reloaded. The matrix metalloproteinase paradox.
Panek, A.N. and Bader, M.
Hypertension 47 (4): 640-641. April 2006

Elevated blood pressure and heart rate in human renin receptor transgenic rats.
Burckle, C.A., Danser, A.H.J., Mueller, D.N., Garrelds, I.M., Gasc, J.M., Popova, E., Plehm, R., Peters, J., Bader, M. and Nguyen, G.
Hypertension 47 (3): 552-556. March 2006

Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.
de Castro, C.H., Souza dos Santos, R.A., Ferreira, A.J., Bader, M., Alenina, N. and de Almeida, A.P.
Hypertension 46 (4): 937-942. 12 September 2005

Role of the B1 kinin receptor in the regulation of cardiac function and remodeling after myocardial infarction.
Xu, J., Carretero, O.A., Sun, Y., Shesely, E.G., Rhaleb, N.E., Liu, Y.H., Liao, T.D., Yang, J.J., Bader, M. and Yang, X.P.
Hypertension 45 (4): 747-753. 1 January 2005

Weight loss and the renin-angiotensin-aldosterone system.
Engeli, S., Boehnke, J., Gorzelniak, K., Janke, J., Schling, P., Bader, M., Luft, F.C. and Sharma, A.M.
Hypertension 45 : 356-362. 1 January 2005

Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney.
Pinheiro, S.V.B., Simoes e Silva, A.C., Sampaio, W.O., de Paula, R.D., Mendes, E.P., Bontempo, E.D., Pesquero, J.B., Walther, T., Alenina, N., Bader, M., Bleich, M. and Santos, R.A.S.
Hypertension 44 (4): 490-496. 1 October 2004

Forced homodimerization by site-directed mutagenesis alters guanylyl cyclase activity of natriuretic peptide receptor B.
Langenickel, T., Buttgereit, J., Pagel, I., Dietz, R., Willenbrock, R. and Bader, M.
Hypertension 43 (2): 460-465. February 2004

Abolition of end-organ damage by antiandrogen treatment in female hypertensive transgenic rats.
Baltatu, O., Cayla, C., Iliescu, R., Andreev, D. and Bader, M.
Hypertension 41 (3): 830-833. March 2003

Delayed maturation of catecholamine phenotype in nucleus tractus solitarius of rats with glial angiotensinogen depletion.
Ogier, M., Bezin, L., Cottet-Emard, J.M., Bader, M., Vincent, M., Pequignot, J.M., McGregor, J. and Bricca, G.
Hypertension 42 (5): 978-984. 1 January 2003

Tonin and kallikrein in the brain of transgenic rat line expressing human tissue kallikrein.
Lomez, E.S.L., Araujo, R.C., Bader, M., Pesquero, J.B. and Pesquero, J.L.
Hypertension 39 : 229-232. 1 January 2002

Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen.
Baltatu, O., Janssen, B.J., Bricca, G., Plehm, R., Monti, J., Ganten, D. and Bader, M.
Hypertension 37 (2): 408-413. 1 January 2001

Interactions between angiotensin-(1-7), kinins, and angiotensin II in kidney and blood vessels.
dos Santos, R.A.S., Passaglio, K.T., Pesquero, J.B., Bader, M. and Silva, A.C.S.E.
Hypertension 38 : 660-664. 1 January 2001

Normal blood pressure and renal function in mice lacking the bradykinin B2 receptor.
Milia, A.F., Gross, V., Plehm, R., De Silva, J.A., Bader, M. and Luft, F.C.
Hypertension 37 : 1473-1479. 1 January 2001

Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Mervaalo, E., Mueller, D.N., Schmidt, F., Park, J.K., Gross, V., Bader, M., Breu, V., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 35 (2): 587-594. 1 February 2000

The brain renin-angiotensin system modulates angiotensin II-induced hypertension and cardiac hypertrophy.
Baltatu, O., Silva, J.A., Ganten, D. and Bader, M.
Hypertension 35 (1): 409-412. 1 January 2000

Transcriptional regulation of the rat renin gene by regulatory elements in intron I.
Voigtlaender, T., Ganten, D. and Bader, M.
Hypertension 33 : 303-311. 1 January 1999

Nitric oxide synthase and renin angiotensin system gene expression in salt-sensitive and salt-resistant Sabra rats.
Lippoldt, A., Gross, V., Schneider, K., Hansson, A.C., Nadaud, S., Schneider, W., Bader, M., Yagil, S.A., Yagil, J. and Luft, F.C.
Hypertension 30 : 409-415. 1 January 1997

Permanent inhibition of angiotensinogen synthesis by antisense RNA expression.
Schinke, M., Boehm, M., Bricca, G., Ganten, D. and Bader, M.
Hypertension 27 : 508-513. 1 January 1996

Differential gene expression of renin and angiotensinogen in the TGR(mREN-2)27 transgenic rat.
Lee, M.A., Boehm, M., Kim, S., Bachmann, S., Bachmann, J., Bader, M. and Ganten, D.
Hypertension 25 : 570-580. 1 January 1995

Mechanism by which angiotensin II stabilizes messenger RNA for angiotensinogen.
Klett, C., Bader, M., Ganten, D. and Hackenthal, E.
Hypertension 23 : I120-I125. 1 January 1994

Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats.
Bader, M., Zhao, Y., Sander, M., Lee, M.A., Bachmann, J., Boehm, M., Djavidani, B., Peters, J., Mullins, J.J. and Ganten, D.
Hypertension 19 (6 Pt 2): 681-686. 1 June 1992

Transgenic rats: new animal models in hypertension research. Invited lecture.
Ganten, D., Lindpaintner, K., Ganten, U., Peters, J., Zimmermann, F., Bader, M. and Mullins, J.J.
Hypertension 17 : 843-855. 1 January 1991

Hypertension Research

Transgenic rat with ubiquitous expression of angiotensin-(1-7)-producing fusion protein: a new tool to study the role of protective arm of the renin-angiotensin system in the pathophysiology of cardio-renal diseases.
Červenka, L., Husková, Z., Kikerlová, S., Gawrys, O., Vacková, Š., Škaroupková, P., Sadowski, J., Miklovič, M., Molnár, M., Táborský, M., Melenovský, V. and Bader, M.
Hypertension Research 13 November 2024 (In Press)

Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension.
Grabowski, K., Herlan, L., Witten, A., Qadri, F., Eisenreich, A., Lindner, D., Schädlich, M., Schulz, A., Subrova, J., Mhatre, K.N., Primessnig, U., Plehm, R., van Linthout, S., Escher, F., Bader, M., Stoll, M., Westermann, D., Heinzel, F.R. and Kreutz, R.
Hypertension Research 45 : 292-307. January 2022

Effects of ACE2 deficiency on physical performance and physiological adaptations of cardiac and skeletal muscle to exercise.
Motta-Santos, D., Dos Santos, R.A.S., Oliveira, M., Qadri, F., Poglitsch, M., Mosienko, V., Kappes Becker, L., Campagnole-Santos, M.J., Penninger, J.M., Alenina, N. and Bader, M.
Hypertension Research 39 (7): 506-512. July 2016

ACE2-angiotensin-(1-7)-Mas axis and oxidative stress in cardiovascular disease.
Rabelo, L.A., Alenina, N. and Bader, M.
Hypertension Research 34 (2): 154-160. February 2011

The role of the renin-angiotensin system in cardiovascular disease.
Bader, M., Wagner, J., Lee, M.A. and Ganten, D.
Hypertension Research 17 : 1-16. 1 January 1994

IEEE Transactions on Applied Superconductivity

Multichannel SQUID system with integrated magnetic shielding for magnetocardiography of mice.
Ackermann, R., Wiekhorst, F., Beck, A., Gutkelch, D., Ruede, F., Schnabel, A., Steinhoff, U., Drung, D., Beyer, J., Assmann, C., Trahms, L., Koch, H., Schurig, T., Fischer, R., Bader, M., Ogata, H. and Kado, H.
IEEE Transactions on Applied Superconductivity 17 (2): 827-830. June 2007

Immunobiology

Mas receptor deficiency exacerbates lipopolysaccharide-induced cerebral and systemic inflammation in mice.
Oliveira-Lima, O.C., Pinto, M.C.X., Duchene, J., Qadri, F., Souza, L.L., Alenina, N., Bader, M., Santos, R.A.S. and Carvalho-Tavares, J.
Immunobiology 220 (12): 1311-1321. December 2015

Immunopharmacology

Myocardial expression of rat bradykinin receptors and two tissue kallikrein genes in experimental diabetes.
Tschoepe, C., Walther, T., Yu, M., Reinecke, A., Koch, M., Seligmann, C., Heringer, S.B., Pesquero, J.B., Bader, M., Schultheiss, H.P. and Unger, T.
Immunopharmacology 44 (1-2): 35-42. 15 October 1999

Upregulation of the cardiac bradykinin B2 receptors after myocardial infarction.
Tschoepe, C., Koch, M., Spillmann, F., Heringer-Walther, S., Mochmann, H.C., Stauss, H., Bader, M., Unger, T., Schultheiss, H.P. and Walther, T.
Immunopharmacology 44 (1-2): 111-117. 15 October 1999

Transcriptional regulatory elements in the rat bradykinin B2 receptor gene.
Pesquero, J.B., Lindsey, C.J., Paiva, A.C.M., Ganten, D. and Bader, M.
Immunopharmacology 33 : 36-41. 1 January 1996

Inflammation Research

Kinins: Locally formed peptides during inflammation with potential use in tissue regeneration.
Martins, L., Bader, M. and Pesquero, J.B.
Inflammation Research 72 (10-11): 1957-1963. November 2023

Kinin receptors regulate skeletal muscle regeneration: differential effects for B1 and B2 receptors.
Martins, L., Amorim, W.W., Gregnani, M.F., de Carvalho Araújo, R., Qadri, F., Bader, M. and Pesquero, J.B.
Inflammation Research 72 (8): 1583-1601. August 2023

Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells.
Guimarães, P.B., da Silva, R.F., Hoff, C.C., Fernandes, L., Nakaie, C.R., Chagas, J.R., Karaoglanovic Carmona, A., Bader, M. and Pesquero, J.B.
Inflammation Research 68 (10): 845-855. October 2019

Bradykinin in health and disease: proceedings of the Bradykinin Symposium 2012, Berlin 23-24 August 2012.
Magerl, M., Bader, M., Gompel, A., Joseph, K., Kaplan, A.P., Kojda, G., Renné, T., Wirth, M., Maurer, M. and Church, M.K.
Inflammation Research 63 (3): 173-8. March 2014

International Immunopharmacology

Essential role of TM V and VI for binding the C-terminal sequences of Des-Arg-kinins.
Santos, E.L., de Picoli Souza, K., Cibrian-Uhalte, E., Oliveira, S.M., Bader, M., Costa-Neto, C.M., Oliveira, L. and Pesquero, J.B.
International Immunopharmacology 8 (2): 282-288. February 2008

KININ2007: Comeback for kinins.
Bader, M.
International Immunopharmacology 8 (2): 133-134. February 2008

Protective actions of human tissue kallikrein gene in transgenic rat hearts.
Silva, J.A., Silva, M.R., Nascimento, J.W., Bader, M. and Pesquero, J.B.
International Immunopharmacology 8 (2): 267-270. February 2008

Roles of the kallikrein/kinin system in the adaptive immune system.
Schulze-Topphoff, U., Prat, A., Bader, M., Zipp, F. and Aktas, O.
International Immunopharmacology 8 (2): 155-160. February 2008

Structure of the mammalian kinin receptor gene locus.
Cayla, C., Merino, V.F., Cabrini, D.A., Silva, J.A., Pesquero, J.B. and Bader, M.
International Immunopharmacology 2 (13-14): 1721-1727. December 2002

Detrimental implication of B-1 receptors in myocardial ischemia: evidence from pharmacological blockade and gene knockout mice.
Lagneux, C., Bader, M., Pesquero, J.B., Demenge, P. and Ribuot, C.
International Immunopharmacology 2 (6): 815-822. May 2002

International Journal of Cancer

Transient inflammatory response induced by apoptotic cells is an important mediator of melanoma cell engraftment and growth.
Correa, M., Machado, J., Carneiro, C.R.W., Pesquero, J.B., Bader, M., Travassos, L.R., Chammas, R. and Jasiulionis, M.G.
International Journal of Cancer 114 (3): 356-363. 1 January 2005

International Journal of Experimental Pathology

Increased aortic intimal proliferation due to MasR deletion in vitro.
Alsaadon, H., Kruzliak, P., Smardencas, A., Hayes, A., Bader, M., Angus, P., Herath, C. and Zulli, A.
International Journal of Experimental Pathology 96 (3): 183-187. June 2015

International Journal of Hypertension

The Angiotensin-melatonin axis.
Campos, L.A., Cipolla-Neto, J., Amaral, F.G., Michelini, L.C., Bader, M. and Baltatu, O.C.
International Journal of Hypertension 2013 : 521783. 2013

Renoprotective effects of AVE0991, a nonpeptide Mas receptor agonist, in experimental acute renal injury.
Barroso, L.C., Silveira, K.D., Lima, C.X., Borges, V., Bader, M., Rachid, M., Souza Santos, R.A., Souza, D.G., Simoes e Silva, A.C. and Teixeira, M.M.
International Journal of Hypertension 2012 : 808726. 2012

International Journal of Molecular Sciences

ACE2 knockout mice are resistant to high-fat diet-induced obesity in an age-dependent manner.
Nunes-Souza, V., Alenina, N., Qadri, F., Mosienko, V., Santos, R.A.S., Bader, M. and Rabelo, L.A.
International Journal of Molecular Sciences 25 (17): 9515. 1 September 2024

Poor decision making and sociability impairment following central serotonin reduction in inducible TPH2-knockdown rats.
Alonso, L., Peeva, P., Fernández-del Valle Alquicira, T., Erdelyi, N., Gil Nolskog, Á., Bader, M., Winter, Y., Alenina, N. and Rivalan, M.
International Journal of Molecular Sciences 25 (9): 5003. May 2024

Effects of bradykinin B2 receptor ablation from tyrosine hydroxylase cells on behavioral and motor aspects in male and female mice.
Franco, T.M., Tavares, M.R., Novaes, L.S., Munhoz, C.D., Peixoto-Santos, J.E., Araujo, R.C., Donato, J., Bader, M. and Wasinski, F.
International Journal of Molecular Sciences 25 (3): 1490. 25 January 2024

Tryptophan hydroxylase-2-mediated serotonin biosynthesis suppresses cell reprogramming into pluripotent state.
Sinenko, S.A., Kuzmin, A.A., Skvortsova, E.V., Ponomartsev, S.V., Efimova, E.V., Bader, M., Alenina, N. and Tomilin, A.N.
International Journal of Molecular Sciences 24 (5): 4862. 2 March 2023

Peripheral serotonin deficiency affects anxiety-like behavior and the molecular response to an acute challenge in rats.
Sbrini, G., Hanswijk, S.I., Brivio, P., Middelman, A., Bader, M., Fumagalli, F., Alenina, N., Homberg, J.R. and Calabrese, F.
International Journal of Molecular Sciences 23 (9): 4941. 29 April 2022

The receptor AT1 appears to be important for the maintenance of bone mass and AT2 receptor function in periodontal bone loss appears to be regulated by AT1 receptor.
Lima, M.L.S., Martins, A.A., Medeiros, C.A.C.X., Guerra, G.C.B., Santos, R., Bader, M., Pirih, F.Q., Araújo Júnior, R.F., Brito, G.A.C., Leitão, R.F.C., Silva, R.A., Barbosa, S.J.A., Melo, R.C.O. and Araújo, A.A.
International Journal of Molecular Sciences 22 (23): 12849. 27 November 2021

In vivo renin activity imaging in the kidney of progeroid Ercc1 mutant mice.
van Thiel, B.S., van der Linden, J., Ridwan, Y., Garrelds, I.M., Vermeij, M., Clahsen-van Groningen, M.C., Qadri, F., Alenina, N., Bader, M., Roks, A.J.M., Danser, A.H.J., Essers, J. and van der Pluijm, I.
International Journal of Molecular Sciences 22 (22): 12433. 18 November 2021

AT1 and AT2 receptor knockout changed osteonectin and bone density in mice in periodontal inflammation experimental model.
Lima, M.L.S., Medeiros, C.A.C.X., Guerra, G.C.B., Santos, R., Bader, M., Pirih, F.Q., Araújo Júnior, R.F., Chan, A.B., Cruz, L.J., Brito, G.A.C., Leitão, R.F.C., Silveira, EJ.D., Garcia, V.B., Martins, A.A. and Araújo, A.A.
International Journal of Molecular Sciences 22 (10): 5217. 14 May 2021

Genetic deletion of trace-amine associated receptor 9 (TAAR9) in rats leads to decreased blood cholesterol levels.
Murtazina, R.Z., Zhukov, I.S., Korenkova, O.M., Popova, E.A., Kuvarzin, S. R., Efimova, E.V., Kubarskaya, L.G., Batotsyrenova, E.G., Zolotoverkhaya, E.A., Vaganova, A.N., Apryatin, S.A., Alenina, N.V. and Gainetdinov, R.R.
International Journal of Molecular Sciences 22 (6): 2942. 2 March 2021

Angiotensin-(1-7) prevents lipopolysaccharide-induced autophagy via the Mas receptor in skeletal muscle.
Rivera, J.C., Abrigo, J., Tacchi, F., Simon, F., Brandan, E., Santos, R.A., Bader, M., Chiong, M. and Cabello-Verrugio, C.
International Journal of Molecular Sciences 21 (24): 9344. 8 December 2020

Short-term western diet aggravates non-alcoholic fatty liver disease (NAFLD) with portal hypertension in TGR(mREN2)27 rats.
Cremonese, C., Schierwagen, R., Uschner, F.E., Torres, S., Tyc, O., Ortiz, C., Schulz, M., Queck, A., Kristiansen, G., Bader, M., Sauerbruch, T., Weiskirchen, R., Walther, T., Trebicka, J. and Klein, S.
International Journal of Molecular Sciences 21 (9): 3308. 1 May 2020

JACC: Basic to Translational Science

Novel tryptophan hydroxylase inhibitor TPT-001 reverses PAH, vascular remodeling, and proliferative-proinflammatory gene expression.
Legchenko, E., Chouvarine, P., Qadri, F., Specker, E., Nazaré, M., Wesolowski, R., Matthes, S., Bader, M. and Hansmann, G.
JACC: Basic to Translational Science 9 (7): 890-902. July 2024

Journal of Anatomy

The role of angiotensin-(1-7) receptor Mas in spermatogenesis in mice and rats.
Leal, M.C., Pinheiro, S.V., Ferreira, A.J., Santos, R.A., Bordoni, L.S., Alenina, N., Bader, M. and Franca, L.R.
Journal of Anatomy 214 (5): 736-743. May 2009

Journal of Applied Physiology

Blood pressure response to chronic episodic hypoxia: the renin-angiotensin system.
Fletcher, E.C., Orolinova, N. and Bader, M.
Journal of Applied Physiology 92 : 627-633. 1 February 2002

Physiological and genomic consequences of intermittent hypoxia - Selected contribution: Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats.
Tahawi, Z., Orolinova, N., Joshua, I.G., Bader, M. and Fletcher, E.C.
Journal of Applied Physiology 90 : 2007-2013. 1 January 2001

Journal of Biological Chemistry

Neurolysin knockout mice generation and initial phenotype characterization.
Cavalcanti, D.M.L.P., Castro, L.M., Rosa Neto, J.C., Seelaender, M., Neves, R.X., Oliveira, V., Forti, F.L., Iwai, L.K., Gozzo, F.C., Todiras, M., Schadock, I., Barros, C.C., Bader, M. and Ferro, E.S.
Journal of Biological Chemistry 289 (22): 15426-15440. 30 May 2014

Regulation of karyopherin alpha1 and nuclear import by mammalian target of rapamycin.
Fielhaber, J.A., Tan, J., Joung, K.B., Attias, O., Huegel, S., Bader, M., Roux, P.P. and Kristof, A.S.
Journal of Biological Chemistry 287 (18): 14325-14335. 27 April 2012

Identification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-AT1, non-AT2 angiotensin binding site.
Wangler, N.J., Santos, K.L., Schadock, I., Hagen, F.K., Escher, E., Bader, M., Speth, R.C. and Karamyan, V.T.
Journal of Biological Chemistry 287 (1): 114-122. 2 January 2012

Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron.
Pohl, M., Kaminski, H., Castrop, H., Bader, M., Himmerkus, N., Bleich, M., Bachmann, S. and Theilig, F.
Journal of Biological Chemistry 285 (53): 41935-41946. 31 December 2010

Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy.
Murtaza, I., Wang, H.X., Feng, X., Alenina, N., Bader, M., Prabhakar, B.S. and Li, P.F.
Journal of Biological Chemistry 283 (10): 5996-6004. 7 March 2008

Functional domains of human tryptophan hydroxylase 2 (hTPH2).
Carkaci-Salli, N., Flanagan, J.M., Martz, M.K., Salli, U., Walther, D.J., Bader, M. and Vrana, K.E.
Journal of Biological Chemistry 281 (38): 28105-28112. 22 September 2006

The vesicular monoamine content regulates VMAT2 activity through G α(q) mouse platelets - evidence for autoregulation of vesicular transmitter update.
Holtje, M., Winter, S., Walther, D., Pahner, I., Hortnagl, H., Ottersen, O.P., Bader, M. and Ahnert-Hilger, G.
Journal of Biological Chemistry 278 (18): 15850-15858. 2 May 2003

Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene.
Martin, G.G., Danneberg, H., Kumar, L.S., Atshaves, B.P., Erol, E., Bader, M., Schroeder, F. and Binas, B.
Journal of Biological Chemistry 278 (24): 21429-21438. 1 January 2003

Proteomic analysis reveals alterations in the renal kallikrein pathway during hypoxia-induced hypertension.
Thongboonkerd, V., Gozal, E., Sachleben, L.R., Arthur, J.M., Pierce, W.M., Cai, J., Chao, J., Bader, M., Pesquero, J.B., Gozal, D. and Klein, J.B.
Journal of Biological Chemistry 277 (38): 34708-34716. 20 September 2002

Sustained long-term potentiation and anxiety in mice lacking the Mas protooncogene.
Walther, T., Balschun, D., Voigt, J.P., Fink, H., Zuschratter, W., Birchmeier, C., Ganten, D. and Bader, M.
Journal of Biological Chemistry 273 : 11867-11873. 1 January 1998

Molecular structure and expression of rat bradykinin B2 receptor gene. Evidence for alterative splicing.
Pesquero, J.B., Lindsey, C.J., Zeh, K., Paiva, A.C.M., Ganten, D. and Bader, M.
Journal of Biological Chemistry 43 : 26920-26925. 1 January 1994

Journal of Bone and Mineral Research

Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5.
Lee, G.S., Simpson, C., Sun, B.H., Yao, C., Foer, D., Sullivan, B., Matthes, S., Alenina, N., Belsky, J., Bader, M. and Insogna, K.L.
Journal of Bone and Mineral Research 29 (4): 976-981. April 2014

Journal of Cachexia Sarcopenia and Muscle

Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K., Kny, M., Huang, N., Klassert, T.E., Stock, M., Hahn, A., Graeger, S., Todiras, M., Schmidt, S., Chamling, B., Willenbrock, M., Groß, S., Biedenweg, D., Heuser, A., Scheidereit, C., Butter, C., Felix, S.B., Otto, O., Luft, F.C., Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12 (6): 1653-1668. December 2021

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting.
Zanders, L., Kny, M., Hahn, A., Schmidt, S., Wundersitz, S., Todiras, M., Lahmann, I., Bandyopadhyay, A., Wollersheim, T., Kaderali, L., Luft, F.C., Birchmeier, C., Weber-Carstens, S. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 13 (1): 713-727. February 2021

Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M., Pablo-Tortola, C., Todiras, M., Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M., Jarosch, E., Sommer, T., Bröker, B.M., Felix, S.B., Scheidereit, C., Weber-Carstens, S., Butter, C., Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 11 (1): 103-119. February 2020

Journal of Cardiovascular Magnetic Resonance

Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy.
Ku, M.C., Kober, F., Lai, Y.C., Pohlmann, A., Qadri, F., Bader, M., Carrier, L. and Niendorf, T.
Journal of Cardiovascular Magnetic Resonance 23 (1): 63. 31 May 2021

Journal of Cardiovascular Pharmacology

Excessive hypertension and end-organ damage in a transgenic mouse line carrying the rat angiotensinogen gene.
Xu, P., Wang, Y., Sterner-Kock, A., Bader, M., Schultheiss, H.P. and Walther, T.
Journal of Cardiovascular Pharmacology 53 (1): 38-43. January 2009

The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of Mas-knockout mice.
Lemos, V.S., Silva, D.M., Walther, T., Alenina, N., Bader, M. and Santos, R.A.
Journal of Cardiovascular Pharmacology 46 (3): 274-279. 1 September 2005

Molecular interactions of vasoactive systems in cardiovascular damage.
Bader, M.
Journal of Cardiovascular Pharmacology 38 (2): S7-S9. 1 January 2001

Journal of Cell Science

Activation of the PTHRP/adenylate cyclase pathway promotes differentiation of rat XEN cells into parietal endoderm, whereas Wnt/β-catenin signaling promotes differentiation into visceral endoderm.
Chuykin, I., Schulz, H., Guan, K. and Bader, M.
Journal of Cell Science 126 (Pt 1): 128-138. 1 January 2013

Journal of Cellular Biochemistry

Targeted genomic integration of EGFP under tubulin beta 3 class III promoter and mEos2 under tryptophan hydroxylase 2 promoter does not produce sufficient levels of reporter gene expression.
Menzorov, A.G., Orishchenko, K.E., Fishman, V.S., Shevtsova, A.A., Mungalov, R.V., Pristyazhnyuk, I.E., Kizilova, E.A., Matveeva, N.M., Alenina, N., Bader, M., Rubtsov, N.B. and Serov, O.L.
Journal of Cellular Biochemistry 120 (10): 17208-17218. October 2019

Journal of Cellular and Molecular Medicine

Hemodynamic stress-induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein.
Mohamed, B.A., Elkenani, M., Mobarak, S., Marques Rodrigues, D., Annamalai, K., Schnelle, M., Bader, M., Hasenfuss, G. and Toischer, K.
Journal of Cellular and Molecular Medicine 26 (16): 4440-4452. August 2022

Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy.
Ni, J., Yang, F., Huang, X.R., Meng, J., Chen, J., Bader, M., Penninger, J.M., Fung, E., Yu, X.Q. and Lan, H.Y.
Journal of Cellular and Molecular Medicine 24 (22): 13093-13103. November 2020

Journal of Cerebral Blood Flow and Metabolism

Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation.
Albert-Weissenberger, C., Stetter, C., Meuth, S.G., Goebel, K., Bader, M., Siren, A.L. and Kleinschnitz, C.
Journal of Cerebral Blood Flow and Metabolism 32 (9): 1747-1756. September 2012

Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation.
Raslan, F., Schwarz, T., Meuth, S.G., Austinat, M., Bader, M., Renne, T., Roosen, K., Stoll, G., Siren, A.L. and Kleinschnitz, C.
Journal of Cerebral Blood Flow and Metabolism 30 (8): 1477-1486. August 2010

The role of bradykinin B(1) and B(2) receptors for secondary brain damage after traumatic brain injury in mice.
Trabold, R., Eroes, C., Zweckberger, K., Relton, J., Beck, H., Nussberger, J., Mueller-Esterl, W., Bader, M., Whalley, E. and Plesnila, N.
Journal of Cerebral Blood Flow and Metabolism 30 (1): 130-139. January 2010

Larger anastomoses in angiotensinogen-knockout mice attenuate early metabolic disturbances after middle cerebral artery occlusion.
Maeda, K., Hata, R., Bader, M., Walther, T. and Hossmann, K.A.
Journal of Cerebral Blood Flow and Metabolism 19 (10): 1092-1098. October 1999

Journal of Clinical Basic Cardiology

Gender-specific alterations of heart rate and blood pressure variability in Mas-deficient mice.
Walter, T., Wessel, N., Kang, N., Sander, A., Malberg, H., Bader, M. and Voss, A.
Journal of Clinical Basic Cardiology 2 (2): 281-282. 1999

Journal of Clinical Endocrinology and Metabolism

A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium.
Kuppusamy, M., Caroccia, B., Stindl, J., Bandulik, S., Lenzini, L., Gioco, F., Fishman, V., Zanotti, G., Gomez-Sanchez, C., Bader, M., Warth, R. and Rossi, G.P.
Journal of Clinical Endocrinology and Metabolism 99 (9): E1765-E1773. September 2014

Lower expression of the Twik-related acid-sensitive K(+) channel 2 (TASK-2) gene is a hallmark of aldosterone producing adenoma causing human primary aldosteronism.
Lenzini, L., Caroccia, B., Campos, A.G., Fassina, A., Belloni, A.S., Seccia, T.M., Kuppusamy, M., Ferraro, S., Skander, G., Bader, M., Rainey, W.E. and Rossi, G.P.
Journal of Clinical Endocrinology and Metabolism 99 (4): E674-E682. April 2014

Journal of Clinical Investigation

CXCL5 limits macrophage foam cell formation in atherosclerosis.
Rousselle, A., Qadri, F., Leukel, L., Yilmaz, R., Fontaine, J.F., Sihn, G., Bader, M., Ahluwalia, A. and Duchene, J.
Journal of Clinical Investigation 123 (3): 1343-1347. 1 March 2013

In vivo bradykinin B2 receptor activation reduces renal fibrosis.
Schanstra, J.P., Neau, E., Drogoz, P., Gomez, M.A.A., Novoa, J.M.L., Calise, D., Pecher, C., Bader, M., Girolami, J.P. and Bascands, J.L.
Journal of Clinical Investigation 110 (3): 371-379. 1 August 2002

Gene expression, localization, and characterization of endothelin A and B receptors in the human adrenal cortex.
Rossi, G.P., Albertin, G., Belloni, A., Zanin, L., Biasolo, M.A., Prayer-Galetti, T., Bader, M., Nussdorfer, G.G., Palu, G. and Pessina, A.C.
Journal of Clinical Investigation 94 (3): 1226-1234. September 1994

Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II and calcium.
Peters, J., Muenter, K., Bader, M., Hackenthal, E., Mullins, J.J. and Ganten, D.
Journal of Clinical Investigation 91 (3): 742-747. March 1993

Journal of Dermatological Science

Kinin receptors in skin wound healing.
da Soley, B., Morais, R.L.T., Pesquero, J.B., Bader, M., Otuki, M.F. and Cabrini, D.A.
Journal of Dermatological Science 82 (2): 95-105. May 2016

B(1) and B(2) kinin receptor participation in hyperproliferative and inflammatory skin processes in mice.
Pietrovski, E.F., Paludo, K.S., Mendes, D.A., Guimaraes, F.D., Veiga, S.S., Buchi, D.D., Fonseca, R.G., Zampronio, A.R., Bader, M., Pesquero, J.B., Ferreira, J., Otuki, M.F. and Cabrini, D.A.
Journal of Dermatological Science 64 (1): 23-30. October 2011

Journal of Endocrinology

Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin angiotensin system.
Santos, R.A.S., Ferreira, A.J., Verano-Braga, T. and Bader, M.
Journal of Endocrinology 216 (2): R1-R17. 18 January 2013

Stress sensitivity is increased in transgenic rats with low brain angiotensinogen.
Mueller, H., Kroeger, J., Joehren, O., Szymczak, S., Bader, M., Dominiak, P. and Raasch, W.
Journal of Endocrinology 204 (1): 85-92. January 2010

Journal of Experimental Medicine

Platelet-derived serotonin links vascular disease and tissue fibrosis.
Dees, C., Akhmetshina, A., Zerr, P., Reich, N., Palumbo, K., Horn, A., Juengel, A., Beyer, C., Kroenke, G., Zwerina, J., Reiter, R., Alenina, N., Maroteaux, L., Gay, S., Schett, G., Distler, O. and Distler, J.H.
Journal of Experimental Medicine 208 (5): 961-972. 9 May 2011

Journal of General Physiology

Angiotensin 1-7 prevents the excessive force loss resulting from 14- and 28-day denervation in mouse EDL and soleus muscle.
Albadrani, H., Ammar, T., Bader, M. and Renaud, J.M.
Journal of General Physiology 153 (12): e201912556. 6 December 2021

Journal of Histochemistry & Cytochemistry

Cell type-specific expression of the Mas proto-oncogene in testis.
Alenina, N., Baranova, T., Smirnow, E., Bader, M., Lippoldt, A., Patkin, E. and Walther, T.
Journal of Histochemistry & Cytochemistry 50 (5): 691-695. May 2002

Journal of Hypertension

Aliskiren accumulation in the kidney: no major role for binding to renin or prorenin.
Lange, S., Fraune, C., Alenina, N., Bader, M., Danser, A.H.J., Frenay, A.R., van Goor, H., Stahl, R., Nguyen, G., Schwedhelm, E. and Wenzel, U.O.
Journal of Hypertension 31 (4): 713-719. April 2013

Blood pressure and renin-angiotensin system resetting in transgenic rats with elevated plasma Val5-angiotensinogen.
Bohlender, J., Bader, M., Menard, J. and Nussberger, J.
Journal of Hypertension 30 (8): 1597-1605. August 2012

Impairment of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension.
Buergelova, M., Vanourkova, Z., Thumova, M., Dvorak, P., Opocensky, M., Kramer, H.J., Zelizko, M., Maly, J., Bader, M. and Cervenka, L.
Journal of Hypertension 27 (10): 1988-2000. October 2009

Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor.
Batenburg, W.W., Krop, M., Garrelds, I.M., de Vries, R., de Bruin, R.J.A., Burckle, C.A., Mueller, D.N., Bader, M., Nguyen, G. and Danser, A.H.J.
Journal of Hypertension 25 (12): 2441-2453. December 2007

Plasma and kidney angiotensin II levels and renal functional responses to AT1 receptor blockade in hypertensive Ren-2 transgenic rats.
Kopkan, L., Kramer, H.J., Huskova, Z., Vanourkova, Z., Baecker, A., Bader, M., Ganten, D. and Cervenka, L.
Journal of Hypertension 22 (4): 819-825. 1 April 2004

Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen.
Couto, A.S., Baltatu, O., Santos, R.A.S., Ganten, D., Bader, M. and Campagnole-Santos, M.J.
Journal of Hypertension 20 (5): 919-925. May 2002

Myocardial bradykinin B2-receptor expression at different time points after induction of myocardial infarction.
Tschoepe, C., Heringer-Walther, S., Koch, M., Spillmann, F., Wendorf, M., Hauke, D., Bader, M., Schultheiss, H.P. and Walther, T.
Journal of Hypertension 18 (2): 223-228. 1 February 2000

Angiotensinogen messenger RNA stabilization by angiotensin II.
Klett, C., Printz, M.P., Bader, M., Ganten, D. and Eggena, P.
Journal of Hypertension 14, Suppl.4 : S25-S36. 1 January 1996

Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions.
Boehm, M., Lee, M.A., Kreutz, R., Kim, S., Schinke, M., Djavidani, B., Wagner, J., Kaling, M., Wienen, W., Bader, M. and Ganten, D.
Journal of Hypertension 13 : 891-899. 1 January 1995

Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27.
Djavidani, B., Sander, M., Kreutz, R., Zeh, K., Bader, M., Mellon, S.H., Vecsei, P., Peters, J. and Ganten, D.
Journal of Hypertension 13 (6): 637-645. 1 January 1995

Basic methodology in the molecular characterization of genes.
Bader, M., Kaling, M., Metzger, R., Peters, J., Wagner, J. and Ganten, D.
Journal of Hypertension 10 : 9-16. 1 January 1992

Journal of Immunology

Anti-inflammatory effects of the activation of the angiotensin-(1-7) receptor, Mas, in experimental models of arthritis.
Silveira, K.D., Coelho, F.M., Vieira, A.T., Sachs, D., Barroso, L.C., Costa, V.V., Bretas, T.L.B., Bader, M., Sousa, L.P., Silva, T.A., Santos, R.A.S., Simoes E Silva, A.C. and Teixeira, M.M.
Journal of Immunology 185 (9): 5569-5576. 1 November 2010

Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin.
Kahn, R., Hellmark, T., Leeb-Lundberg, L.M., Akbari, N., Todiras, M., Olofsson, T., Wieslander, J., Christensson, A., Westman, K., Bader, M., Mueller-Esterl, W. and Karpman, D.
Journal of Immunology 182 (12): 7906-7915. 15 June 2009

A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5.
Duchene, J., Lecomte, F., Ahmed, S., Cayla, C., Pesquero, J., Bader, M., Perretti, M. and Ahluwalia, A.
Journal of Immunology 179 (7): 4849-4856. 1 October 2007

Role of bradykinin B2 and B1 receptors in the local, remote, and systemic inflammatory responses that follow intestinal ischemia and reperfusion injury.
Souza, D.G., Lomez, E.S.L., Pinho, V., Pesquero, J.B., Bader, M., Pesquero, J.L. and Teixeira, M.M.
Journal of Immunology 172 (4): 2542-2548. 1 January 2004

Journal of Infectious Diseases

Importin-α7 is involved in the formation of Ebola virus inclusion bodies but is not essential for pathogenicity in mice.
Gabriel, G., Feldmann, F., Reimer, R., Thiele, S., Fischer, M., Hartmann, E., Bader, M., Ebihara, H., Hoenen, T. and Feldmann, H.
Journal of Infectious Diseases 212 (Suppl 2): S316-S321. 1 October 2015

Journal of Medical Genetics

We need a detailed phenome in the phenomenon of genetics and congenital heart disease.
Posch, M.G., Berger, F., Perrot, A. and Oezcelik, C.
Journal of Medical Genetics 45 (5): 320. May 2008

Journal of Medicinal Chemistry

Structure-based design of xanthine-imidazopyridines and -imidazothiazoles as highly potent and in vivo efficacious tryptophan hydroxylase inhibitors.
Specker, E., Wesolowski, R., Schütz, A., Matthes, S., Mallow, K., Wasinska-Kalwa, M., Winkler, L., Oder, A., Alenina, N., Pleimes, D., von Kries, J.P., Heinemann, U., Bader, M. and Nazaré, M.
Journal of Medicinal Chemistry 66 (21): 14866-14896. 9 November 2023

Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
Specker, E., Matthes, S., Wesolowski, R., Schütz, A., Grohmann, M., Alenina, N., Pleimes, D., Mallow, K., Neuenschwander, M., Gogolin, A., Weise, M., Pfeifer, J., Ziebart, N., Heinemann, U., von Kries, J.P., Nazaré, M. and Bader, M.
Journal of Medicinal Chemistry 65 (16): 11126-11149. 25 August 2022

Journal of Molecular Biology

Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome.
Chan, J.C., Alenina, N., Cunningham, A.M., Ramakrishnan, A., Shen, Li, Bader, M. and Maze, I.
Journal of Molecular Biology 436 (7): 168454. 1 April 2024

Community-wide experimental evaluation of the PROSS stability-design method.
Peleg, Y., Vincentelli, R., Collins, B.M., Chen, K.E., Livingstone, E.K., Weeratunga, S., Leneva, N., Guo, Q., Remans, K., Perez, K., Bjerga, G.E.K., Larsen, Ø., Vaněk, O., Skořepa, O., Jacquemin, S., Poterszman, A., Kjaer, S., Christodoulou, E., Albeck, S., Dym, O., Ainbinder, E., Unger, T., Schuetz, A., Matthes, S., Bader, M., de Marco, A., Storici, P., Semrau, M.S., Stolt-Bergner, P., Aigner, C., Suppmann, S., Goldenzweig, A. and Fleishman, S.J.
Journal of Molecular Biology 433 (13): 166964. 25 June 2021

Journal of Molecular Endocrinology

Contribution of A 12 kDa protein to the angiotensin II-induced stabilization of angiotensinogen mRNA : interaction with the 3'untranslated mRNA.
Klett, C., Bader, M., Schwemmle, M., Ganten, D. and Hackenthal, E.
Journal of Molecular Endocrinology 14 : 209-226. 1 January 1995

Journal of Molecular Medicine

Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II.
Maier, C., Schadock, I., Haber, P.K., Wysocki, J., Ye, M., Kanwar, Y., Flask, C.A., Yu, X., Hoit, B.D., Adams, G.N., Schmaier, A.H., Bader, M. and Batlle, D.
Journal of Molecular Medicine 95 (5): 473-486. May 2017

Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction.
Mühlstedt, S., Ghadge, S.K., Duchene, J., Qadri, F., Järve, A., Vilianovich, L., Popova, E., Pohlmann, A., Niendorf, T., Boyé, P., Özcelik, C. and Bader, M.
Journal of Molecular Medicine 94 (9): 1005-1014. September 2016

Receptors, G proteins, and integration of calcium signalling.
Gudermann, T. and Bader, M.
Journal of Molecular Medicine 93 (9): 937-940. September 2015

Oral administration of angiotensin-(1-7) ameliorates type 2 diabetes in rats.
Santos, S.H.S., Giani, J.F., Burghi, V., Miquet, J.G., Qadri, F., Braga, J.F., Todiras, M., Kotnik, K., Alenina, N., Dominici, F.P., Santos, R.A.S. and Bader, M.
Journal of Molecular Medicine 92 (3): 255-265. March 2014

Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D., Luft, F.C., Bader, M., Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90 (5): 495-508. May 2012

ACE activity is modulated by the enzyme alpha-galactosidase A.
Batista, E.C., Carvalho, L.R., Casarini, D.E., Carmona, A.K., Dos Santos, E.L., da Silva, E.D., Dos Santos, R.A., Nakaie, C.R., Rojas, M.V., de Oliveira, S.M., Bader, M., D'Almeida, V., Martins, A.M., de Picoly Souza, K. and Pesquero, J.B.
Journal of Molecular Medicine 89 (1): 65-74. January 2011

Leptin regulates ACE activity in mice.
Hilzendeger, A.M., Morais, R.L., Todiras, M., Plehm, R., da Costa Goncalves, A., Qadri, F., Araujo, R.C., Gross, V., Nakaie, C.R., Casarini, D.E., Carmona, A.K., Bader, M. and Pesquero, J.B.
Journal of Molecular Medicine 88 (9): 899-907. September 2010

Autonomic dysregulation in ob/ob mice is improved by inhibition of angiotensin-converting enzyme.
Hilzendeger, A.M., da Costa Goncalves, A.C., Plehm, R., Diedrich, A., Gross, V., Pesquero, J.B. and Bader, M.
Journal of Molecular Medicine 88 (4): 383-390. April 2010

Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E.
Merino, V.F., Todiras, M., Mori, M.A., Sales, V.M., Fonseca, R.G., Saul, V., Tenner, K., Bader, M. and Pesquero, J.B.
Journal of Molecular Medicine 87 (10): 953-963. October 2009

Increased susceptibility to endotoxic shock in transgenic rats with endothelial overexpression of kinin B(1) receptors.
Merino, V.F., Todiras, M., Campos, L.A., Saul, V., Popova, E., Baltatu, O.C., Pesquero, J.B. and Bader, M.
Journal of Molecular Medicine 86 (7): 791-798. July 2008

An old couple: the renin-angiotensin system (RAS) and the Journal of Molecular Medicine (JMolMed).
Ganten, D., Bader, M. and Juergensen, J.S.
Journal of Molecular Medicine 86 (6): 609-610. June 2008

Update on tissue renin-angiotensin systems.
Bader, M. and Ganten, D.
Journal of Molecular Medicine 86 (6): 615-621. June 2008

Plasticity and impact of the central renin-angiotensin system during development of ethanol dependence.
Sommer, W.H., Rimondini, R., Marquitz, M., Lidstroem, J., Siems, W.E., Bader, M. and Heilig, M.
Journal of Molecular Medicine 85 (10): 1089-1097. October 2007

Natriuretic peptide receptor B signaling in the cardiovascular system: protection from cardiac hypertrophy.
Pagel-Langenickel, I., Buttgereit, J., Bader, M. and Langenickel, T.H.
Journal of Molecular Medicine 85 (8): 797-810. August 2007

Functional characterization of the human atrial essential myosin light chain (hALC-1) in a transgenic rat model.
Abdelaziz, A.I., Segaric, J., Bartsch, H., Petzhold, D., Schlegel, W., Kott, M., Seefeldt, I., Klose, J., Bader, M., Haase, H. and Morano, I.
Journal of Molecular Medicine 82 (4): 265-274. 1 January 2004

Androgen receptor independent cardiovascular action of the antiandrogen flutamide.
Iliescu, R., Campos, L.A., Schlegel, W.P., Morano, I., Baltatu, O. and Bader, M.
Journal of Molecular Medicine 81 (7): 420-427. July 2003

Reduced hypertension-induced end-organ damage in mice lacking cardiac and renal angiotensinogen synthesis.
Kang, N.L., Walther, T., Tian, X.L., Bohlender, J., Fukamizu, A., Ganten, D. and Bader, M.
Journal of Molecular Medicine 80 (6): 359-366. June 2002

Embryonic stem cells share immune-privileged features relevant for tolerance induction.
Faendrich, F., Dresske, B., Bader, M. and Schulze, M.
Journal of Molecular Medicine 80 (6): 343-350. 1 January 2002

Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research.
Bader, M., Peters, J., Baltatu, O., Mueller, D.N., Luft, F.C. and Ganten, D.
Journal of Molecular Medicine 79 (2): 76-102. 1 January 2001

Regulation of renin: new evidence from cultured cells and genetically modified mice.
Bader, M. and Ganten, D.
Journal of Molecular Medicine 78 (3): 130-139. 1 January 2000

Journal of Molecular and Cellular Cardiology

Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease.
Gramlich, M., Michely, B., Krohne, C., Heuser, A., Erdmann, B., Klaassen, S., Hudson, B., Magarin, M., Kirchner, F., Todiras, M., Granzier, H., Labeit, S., Thierfelder, L. and Gerull, B.
Journal of Molecular and Cellular Cardiology 47 (3): 352-358. September 2009

Role of the local renin-angiotensin system in cardiac damage: a minireview focussing on transgenic animal models.
Bader, M.
Journal of Molecular and Cellular Cardiology 34 (11): 1455-1462. November 2002

Journal of Neurochemistry

The activity of the STriatal-Enriched protein tyrosine Phosphatase (STEP) in neuronal cells is modulated by adenosine A(2A) receptor.
Mallozzi, C., Pepponi, R., Visentin, S., Chiodi, V., Lombroso, P.J., Bader, M., Popoli, P. and Domenici, M.R.
Journal of Neurochemistry 152 (3): 284-298. February 2020

Striatal adenosine-cannabinoid receptor interactions in rats overexpressing adenosine A2A receptors.
Chiodi, V., Ferrante, A., Ferraro, L., Potenza, R.L., Armida, M., Beggiato, S., Pezzola, A., Bader, M., Fuxe, K., Popoli, P. and Domenici, M.R.
Journal of Neurochemistry 136 (5): 907-917. March 2016

Discovering the mechanisms underlying serotonin (5-HT)2A and 5-HT2C receptor regulation following nicotine withdrawal in rats.
Zaniewska, M., Alenina, N., Wydra, K., Fröhler, S., Kuśmider, M., McCreary, A.C., Chen, W., Bader, M. and Filip, M.
Journal of Neurochemistry 134 (4): 704-716. August 2015

Influence of human tryptophan hydroxylase 2 N- and C-terminus on enzymatic activity and oligomerization.
Tenner, K., Walther, D. and Bader, M.
Journal of Neurochemistry 102 (6): 1887-1894. September 2007

Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation.
Zhao, Y., Foryst-Ludwig, A., Bruemmer, D., Culman, J., Bader, M., Unger, T. and Kintscher, U.
Journal of Neurochemistry 94 (5): 1395-1401. 30 June 2005