Items where Year is 2025

A

Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing.
Abay, T., Stickels, R.R., Takizawa, M.T., Nalbant, B.N., Hsieh, Y.H., Hwang, S., Snopkowski, C., Yu, K.K.H., Abou-Mrad, Z., Tabar, V., Howitt, B.E, Ludwig, L.S., Chaligné, R., Satpathy, A.T and Lareau, C.A.
Nature Genetics 57 (2): 451-460. February 2025

Clonal driver neoantigen loss under EGFR TKI and immune selection pressures.
Al Bakir, M., Reading, J.L., Gamble, S., Rosenthal, R., Uddin, I., Rowan, A., Przewrocka, J., Rogers, A., Wong, Y.N.S., Bentzen, A.K., Veeriah, S., Ward, S., Garnett, A.T., Kalavakur, P., Martínez-Ruiz, C., Puttick, C., Huebner, A., Cook, D.E., Moore, D.A., Abbosh, C., Hiley, C.T., Naceur-Lombardelli, C., Watkins, T.B.K., Petkovic, M., Schwarz, R.F., Gálvez-Cancino, F., Litchfield, K., Meldgaard, P., Sorensen, B.S., Madsen, L.B., Jäger, D., Forster, M.D., Arkenau, T., Domingo-Vila, C., Tree, T.I.M., Kadivar, M., Hadrup, S.R., Chain, B., Quezada, S.A., McGranahan, N. and Swanton, C.
Nature 19 February 2025 (In Press)

Targeting autoimmunity with CD19-CAR T cell therapy: efficacy and seroconversion in diffuse systemic sclerosis and rheumatoid arthritis.
Albach, F.N., Minopoulou, I., Wilhelm, A., Biesen, R., Kleyer, A., Wiebe, E., Fleischmann, A., Frick, M., Damm, F., Gogolok, J., Serve, S., Locher, B.N., Borie, D., Casteleyn, V., Siegert, E., Dörner, T., Alexander, T., Furth, C., Zernicke, J., Movassaghi, K., Hütter-Krönke, M.L., Schrezenmeier, E., Schneider, U., Bullinger, L., Krönke, G., Penack, O. and Simon, D.
Rheumatology : keaf077. 10 February 2025 (In Press)

Merkel cell polyomavirus infection and persistence modelled in skin organoids.
Albertini, S., Czech-Sioli, M., Guenther, T., Virdi, S., Blümke, P., Röpke, L., Brinschwitz, V., Dandri, M., Allweiss, L., Reimer, R., Schneider, C., Hansen, A., Krasemann, S., Wyler, E., Landthaler, M., Grundhoff, A. and Fischer, N.
bioRxiv : 2025.02.11.637697. 12 February 2025

Distinguishing neuromyelitis optica spectrum disorders subtypes: a study on AQP4 and C3d epitope expression in cytokine-primed human astrocytes.
Alisch, M., Foersterling, F., Zocholl, D., Muinjonov, B., Schindler, P., Duchnow, A., Otto, C., Ruprecht, K., Schmitz-Hübsch, T., Jarius, S., Paul, F. and Siffrin, V.
Glia 27 January 2025 (In Press)

Acute optogenetic stimulation of serotonin neurons reduces cell proliferation in the dentate gyrus of mice.
Araragi, N., Petermann, M., Suzuki, M., Larkum, M., Mosienko, V., Bader, M., Alenina, N. and Klempin, F.
ACS Chemical Neuroscience 12 February 2025 (In Press)

Food allergy genetics and epigenetics: a review of genome-wide association studies.
Arnau-Soler, A., Tremblay, B.L., Sun, Y., Madore, A.M., Simard, M., Kersten, E.T.G., Ghauri, A., Marenholz, I., Eiwegger, T., Simons, E., Chan, E.S., Nadeau, K., Sampath, V., Mazer, B.D., Elliott, S., Hampson, C., Soller, L., Sandford, A., Begin, P., Hui, J., Wilken, B.F., Gerdts, J., Bourkas, A., Ellis, A.K., Vasileva, D., Clarke, A., Eslami, A., Ben-Shoshan, M., Martino, D., Daley, D., Koppelman, G.H., Laprise, C., Lee, Y.A. and Asai, Y.
Allergy 80 (1): 106-131. January 2025

Prediction of central post-stroke pain by quantitative sensory testing.
Asseyer, S., Panagoulas, E., Maidhof, J., Villringer, K., Al, E., Chen, X., Krause, T., Hardikar, S., Villringer, A. and Jungehülsing, G.J.
Annals of Neurology 97 (3): 507-520. March 2025 (In Press)

Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface.
Avery, E.G., Haag, L.M., McParland, V., Kedziora, S.M., Zigra, G.J., Valdes, D.S., Kirchner, M., Popp, O., Geisberger, S., Nonn, O., Karlsen, T.V., N'Diaye, G., Yarritu, A., Bartolomaeus, H., Bartolomaeus, T.U.P., Tagiyeva, N.A., Wimmer, M.I., Haase, N., Zhang, Y.D., Wilhelm, A., Grütz, G., Tenstad, O., Wilck, N., Forslund, S.K., Klopfleisch, R., Kühl, A.A., Atreya, R., Kempa, S., Mertins, P., Siegmund, B., Wiig, H. and Müller, D.N.
Cardiovascular Research : cvae267. 13 January 2025 (In Press)

B

A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells.
Babin-Ebell Gonçalves, A., Mao, Y., Baljkas, T., Wiedmann, F., Eis, L., Winkler, M., Pilz, F., Kürschner-Zacharias, S.W., Hoffarth, M., Funaya, C., Shahidi, R., Géraud, C., Wu, C.C., Schmidt, C., Goerdt, S., Reiners-Koch, P.S. and Singhal, M.
Communications Biology 8 (1): 22. 8 January 2025

Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease.
Bao, L.L., Yu, Y.Q., González-Acera, M., Patankar, J.V., Giessl, A., Sturm, G., Kühl, A.A., Atreya, R., Erkert, L., Gámez-Belmonte, R., Krug, S.M., Schmid, B., Tripal, P., Chiriac, M.T., Hildner, K., Siegmund, B., Wirtz, S., Stürzl, M., Mohamed Abdou, M., Trajanoski, Z., Neurath, M.F., Zorzano, A. and Becker, C.
Science Translational Medicine 17 (781): eadn8699. January 2025

Dissecting the role of RNA-binding proteins in early herpes simplex virus 1 transcription using acute protein depletion.
Barke, N, Masser, S., Stalling, D., Wyler, E., Zinzen, R.P., Schreiner, S., Bosse, J. and Landthaler, M.
bioRxiv : 2025.02.10.637450. 11 February 2025

Association of peripapillary retinal nerve fiber layer atrophy with cognitive impairment in patients with neuromyelitis optica spectrum disorder.
Barzegar, M., Ashtari, F., Kafieh, R., Karimi, Z., Dehghani, A., Ghalamkari, A., Afshari-Safavi, A. and Paul, F.
Neurological Sciences 46 (2): 861-870. February 2025

Clinical implications of genetic discoveries on frontal fibrosing alopecia.
Basmanav, F.B., Lee, Y.A. and Betz, R.C.
JAMA Dermatology 12 February 2025 (In Press)

Identification of TTLL8, POTEE, and PKMYT1 as immunogenic cancer-associated antigens and potential immunotherapy targets in ovarian cancer.
Bassoy, E.Y., Raja, R., Rubino, T.E., Coscia, F., Goergen, K., Magtibay, P., Butler, K., Schmitt, A., Oberg, A.L. and Curtis, M.
OncoImmunology 14 (1): 2460276. December 2025

High Ano1 expression as key driver of resistance to radiation and cisplatin in HPV-negative head and neck squamous cell carcinoma.
Bourdier, S., Fisch, A.S., Alp, K.M., Das, R., Mertins, P. and Tinhofer, I.
Scientific Reports 15 (1): 1555. 10 January 2025

C

How to avoid missing a diagnosis of neuromyelitis optica spectrum disorder.
Carnero Contentti, E., Rotstein, D., Okuda, D.T. and Paul, F.
Multiple Sclerosis Journal 31 (1): 8-22. January 2025

Extrachromosomal circular DNA promotes inflammation and hepatocellular carcinoma development.
Chan, L.K., Shan, J., Rodriguez-Fos, E., Healy, M., Leary, P., Parrotta, R., Desboeufs, N., Semere, G., Wittstruck, N., Henssen, A. and Weber, A.
bioRxiv : 2025.01.22.634016. 24 January 2025

Rethinking animal attrition in preclinical research: expressing causal mechanisms of selection bias using directed acyclic graphs.
Collazo, A., Kuhn, H.G., Kurth, T., Piccininni, M. and Rohmann, J.L.
Journal of Cerebral Blood Flow and Metabolism 45 (2): 340-351. February 2025

D

Ten years of Neurology® Neuroimmunology & Neuroinflammation: decade in review.
Dalmau, J., Dalakas, M.C., Kolson, D.L., Pröbstel, A.K., Paul, F. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 12 (1): e200363. January 2025

Concurrent profiling of localized transcriptome and RNA dynamics in neurons by spatial SLAMseq.
Dantsuji, S. and Chekulaeva, M.
Methods in Molecular Biology 2863 : 297-317. 2025

E

The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes.
Eibach, Y., Kreher, S., Poetsch, M.S., Kho, A.L., Gaertner, U., Clemen, C.S., Schröder, R., Guo, K., Milting, H., Meder, B., Potente, M., Richter, M., Schneider, A., Meiners, S., Gaute, M. and Braun, T.
Science Advances 11 (4): eado3852. 24 January 2025

Targeting Runx1 protects against heart failure with preserved ejection fraction.
Elbassioni, A.A.M., Raheem, A.A., Song, J., Johnston, A.S., Trivett, C., Lin, H., Zhang, H., Bradley, A., Higgins, E., Mooney, L., Koay, Y.C., O'Toole, D., Herzyk, P., Nixon, C., Blyth, K., O'Sullivan, J.F., Lang, N.N., Berry, C., Braun, T., Schiattarella, G.G., Giacca, M., McBride, M.W., Nicklin, S.A., Cameron, E.R., Loughrey, C.M. and MacDonald, E.A.
bioRxiv : 2025.01.24.634831. 27 January 2025

TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice.
Erkert, L., Ruder, B., Kabisch, M., Gamez Belmonte, R., Patankar, J.V., Gonzalez Acera, M., Schödel, L., Chiriac, M.T., Cineus, R., Gnafakis, S., Leupold, T., Thoma, O.M., Stolzer, I., Taut, A., Thonn, V., Zundler, S., Günther, C., Diefenbach, A., Kühl, A.A., Hegazy, A.N., Waldner, M., Basic, M., Bleich, A., Neurath, M.F., Wirtz, S. and Becker, C.
Mucosal Immunology 20 January 2025 (In Press)

Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy.
Escobar, H., Di Francescantonio, S., Smirnova, J., Graf, R., Müthel, S., Marg, A., Zhogov, A., Krishna, S., Metzler, E., Petkova, M., Daumke, O., Kühn, R. and Spuler, S.
Nature Communications 16 (1): 120. 2 January 2025

Touch inhibits cold: non-contact cooling suggests a thermotactile gating mechanism.
Ezquerra Romano, I., Chowdhury, M. and Haggard, P.
Proceedings of the Royal Society B: Biological Sciences 292 (2040): 20243014. February 2025

F

Response to the letter to the editor: "cardiovascular magnetic resonance reveals myocardial involvement in patients with active stage of inflammatory bowel disease" (CRCD-D-24-01694).
Fenski, M. and Schulz-Menger, J.
Clinical Research in Cardiology 5 February 2025 (In Press)

Comprehensive cerebrospinal fluid analysis indicates key roles for B cells in multiple sclerosis.
Fernández-Zapata, C., Otto, C., Gallaccio, G., Chen, Q., Wang, M., Uluvar, B., Teves, M., Samol, C., Buthut, M., Bösl, F.R., Dehlinger, A., Jang, G.H., Böttcher, C., Radbruch, H., Priller, J., Schindler, P., Raposo, C., Shippling, S., Pedotti, R., Kunkel, D., Pietzner, M., Franke, C., Oefner, P.J., Gronwald, W., Prüß, H., Lohmeier, J., Paul, F., Ruprecht, K. and Böttcher, C.
medRxiv : 2025.01.02.24319302. 6 January 2025

Early-life adversity predicts markers of aging-related neuroinflammation, neurodegeneration, and cognitive impairment in women.
Fleck, L., Buss, C., Bauer, M., Stein, M., Mekle, R., Kock, L., Klawitter, H., Godara, M., Ramler, J., Entringer, S., Endres, M. and Heim, C.
Annals of Neurology 9 January 2025 (In Press)

Loss of structural specificity in 3D genome organization upon viral infection is predicted by polymer physics.
Fontana, A., Bianco, S., Tafuri, F., Esposito, A., Abraham, A., Conte, M., Vercellone, F., Di Pierno, F., Kundu, S., Guha, S., Di Carluccio, C., Prisco, A., Nicodemi, M. and Chiariello, A.M.
Journal of Chemical Physics 162 (1): 014903. 7 January 2025

Sex hormone-dependent host-microbiome interactions and cardiovascular risk (XCVD): design of a longitudinal multi-omics cohort study.
Franz, K., Markó, L., Mähler, A., Chakaroun, R., Heinitz, S., Schlögl, H., Sacher, J., Steckhan, N., Dechend, R., Adams, N., Andersen, M., Glintborg, D., Viehweger, M., Bahr, L.S. and Forslund-Startceva, S.K.
BMJ Open 15 (1): e087982. 9 January 2025

G

Deuterated oxazines are bright near-infrared fluorophores for mitochondrial imaging and single molecule spectroscopy.
Gatin-Fraudet, B., Seifert, J., Sarach, K., Olesen, C.H., Birke, R., Milles, S., Birol, M., Lehmann, M. and Broichhagen, J.
Chemical Communications 61 (17): 3540-3543. 20 February 2025

Stress CMR perfusion imaging in the medicare-eligible population: insights from the SPINS study.
Ge, Y., Antiochos, P., Bernhard, B., Heydari, B., Steel, K., Bingham, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Shanbhag, S.M., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 18 (1): 33-44. January 2025

Polarity-JaM: an image analysis toolbox for cell polarity, junction and morphology quantification.
Giese, W., Albrecht, J.P., Oppenheim, O., Akmeriç, E.B., Kraxner, J., Schmidt, D., Harrington, K.I. and Gerhardt, H.
Nature Communications 16 (1): 1474. 8 February 2025

Costs associated with insufficient physical activity in Germany: cross-sectional results from the baseline examination of the German national cohort (NAKO).
Gottschalk, S., König, H.H., Weber, A., Leitzmann, M.F., Stein, M.J., Peters, A., Flexeder, C., Krist, L., Willich, S.N., Nimptsch, K., Pischon, T., Gastell, S., Steindorf, K., Herbolsheimer, F., Ebert, N., Michels, K.B., Dorrn, A., Harth, V., Obi, N., Karch, A., Teismann, H., Völzke, H., Meinke-Franze, C., Klimeck, L., Seum, T.L. and Dams, J.
European Journal of Health Economics 26 (1): 117-128. February 2025

Detecting unforeseen data properties with diffusion autoencoder embeddings using spine MRI data.
Graf, R., Hunecke, F., Pohl, S., Atad, M., Moeller, H., Starck, S., Kroencke, T., Bette, S., Bamberg, F., Pischon, T., Niendorf, T., Schmidt, C., Paetzold, J.C., Rueckert, D. and Kirschke, J.S.
Lecture Notes in Computer Science 2024 (15274): 79-88. 17 January 2025

Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy.
Grunewald, L., Andersch, L., Helmsauer, K., Schwiebert, S., Klaus, A., Henssen, A.G., Straka, T., Lodrini, M., Wicha, S.G., Fuchs, S., Hertwig, F., Westermann, F., Vitali, A., Caramel, C., Büchel, G., Eilers, M., Astrahantseff, K., Eggert, A., Höpken, U.E., Schulte, J.H., Blankenstein, T., Anders, K. and Künkele, A.
Pharmacological Research 212 : 107608. February 2025

Generation of a human induced pluripotent stem cell line (BIHi292-A) from PBMCs of a female patient diagnosed with Nasu-Hakola disease (NHD)/polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) carrying a novel heterozygous mutation in the TREM2 gene.
Göttert, R., Vallone, V.F., Stachelscheid, H., Metzger, J.J., Caedo, C.C., Buthut, M., Prüss, H., Endres, M., Schilling, S. and Gertz, K.
Stem Cell Research 83 : 103660. March 2025

H

Gonadal sex and temperature independently influence germ cell differentiation and meiotic progression in Trachemys scripta.
Hatkevich, T., Tezak, B.M., Acemel, R.D., Yee Chung, V.W., Lupiáñez, D.G. and Capel, B.
Proceedings of the National Academy of Sciences of the United States of America 122 (1): e2413191121. 7 January 2025

Next generation concepts in dermal delivery, theranostics, and preclinical testing.
Hedtrich, S. and Calderón, M.
Advanced Drug Delivery Reviews 217 : 115482. February 2025

Preventive effects of botulinum neurotoxin long-term therapy: comparison of the ‘experienced’ benefits and ‘suspected’ worsening across disease entities.
Hefter, H. and Samadzadeh, S.
Journal of Clinical Medicine 14 (2): 480. January 2025

Serially quantifying TERT rearrangement breakpoints in circulating tumor DNA enables minimal residual disease monitoring in patients with neuroblastoma.
Hollander, J.F., Szymansky, A., Wünschel, J., Astrahantseff, K., Rosswog, C., Thorwarth, A., Thole-Kliesch, T.M., Chamorro Gonzalez, R., Hundsdörfer, P., Hauptmann, K., Schmelz, K., Gürgen, D., Rogasch, J.M.M., Henssen, A.G., Fischer, M., Schulte, J.H., Eckert, C., Eggert, A., Lodrini, M. and Deubzer, H.E.
Cancer Research Communications 5 (1): 167-177. 28 January 2025

Gut-derived metabolites as treatment targets in chronic kidney disease - an avenue toward personalized medicine.
Holle, J. and Bartolomaeus, H.
Pediatric Nephrology 16 January 2025 (In Press)

Gut microbiome alterations precede graft rejection in kidney transplantation patients.
Holle, J., Reitmeir, R., Behrens, F., Singh, D., Schindler, D., Potapenko, O., McParland, V., Anandakumar, H., Kanzelmeyer, N., Sommerer, C., Hartleif, S., Andrassy, J., Heemann, U., Neuenhahn, M., Forslund-Startceva, S.K., Gerhard, M., Oh, J., Wilck, N., Löber, U. and Bartolomaeus, H.
American Journal of Transplantation 18 February 2025 (In Press)

Esophageal adenocarcinoma relapse after chemoradiation is dominated by a basal-like subtype.
Hoppe, S., Noseir, S., Yazbeck, A., Zaburannyi, N., Grossbach, J., Lyu, S.I., Velazquez Camacho, O., Müller, S., Gebauer, F., Richartz, V., Holz, B., Berg, J., Achter, V., Altmüller, J., Becker, K., Arolt, C., Meder, L., Zhao, Y., Schlößer, H., Baus, W.W., Kamp, F., Baues, C., Beyer, A., Odenthal, M., Quaas, A., Buettner, R. and Hillmer, A.M.
bioRxiv : 2025.01.28.635332. 1 February 2025

Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4(+) T cells as predictors for response to integrin α4β7-blocking therapy in inflammatory bowel disease.
Horn, V., Cancino, C.A., Steinheuer, L.M., Obermayer, B., Fritz, K., Nguyen, A.L., Juhran, K.S., Plattner, C., Bösel, D., Oldenburg, L., Burns, M., Schulz, A.R., Saliutina, M., Mantzivi, E., Lissner, D., Conrad, T., Mashreghi, M.F., Zundler, S., Sonnenberg, E., Schumann, M., Haag, L.M., Beule, D., Flatz, L., Trjanoski, Z., D'Haens, G., Weidinger, C., Mei, H.E., Siegmund, B., Thurley, K. and Hegazy, A.N.
Gastroenterology 168 (2): 327-343. February 2025

T cell receptors specific for an imatinib-induced mutation in BCR-ABL for adoptive T cell therapy.
Hsu, M.T., Willimsky, G., Hansmann, L. and Blankenstein, T.
Frontiers in Immunology 16 : 1518691. 27 January 2025

I

In vivo base editing reduces liver cysts in autosomal dominant polycystic kidney disease.
Ibel, A., Bhardwaj, R., Yilmaz, D.E., Kong, S., Wendlinger, S., Papaioannou, D., Diezemann, C., Eckardt, K.U., Hasan, F., Klämbt, V., Halbritter, J., Fedeles, S., Krappitz, M. and Kaminski, M.M.
bioRxiv : 2025.02.07.636600. 8 February 2025

J

Unraveling the distinctive gut microbiome of khulans (Equus hemionus hemionus) in comparison to their drinking water and closely related equids.
Jarquín-Díaz, V.H., Dayaram, A., Soilemetzidou, E.S., Desvars-Larrive, A., Bohner, J., Buuveibaatar, B., Kaczensky, P., Walzer, C., Greenwood, A.D. and Löber, U.
Scientific Reports 15 (1): 2767. 22 January 2025

Engineered heart muscle allografts for heart repair in primates and humans.
Jebran, A.F., Seidler, T., Tiburcy, M., Daskalaki, M., Kutschka, I., Fujita, B., Ensminger, S., Bremmer, F., Moussavi, A., Yang, H., Qin, X., Mißbach, S., Drummer, C., Baraki, H., Boretius, S., Hasenauer, C., Nette, T., Kowallick, J., Ritter, C.O., Lotz, J., Didié, M., Mietsch, M., Meyer, T., Kensah, G., Krüger, D., Sakib, M.S., Kaurani, L., Fischer, A., Dressel, R., Rodriguez-Polo, I., Stauske, M., Diecke, S., Maetz-Rensing, K., Gruber-Dujardin, E., Bleyer, M., Petersen, B., Roos, C., Zhang, L., Walter, L., Kaulfuß, S., Yigit, G., Wollnik, B., Levent, E., Roshani, B., Stahl-Henning, C., Ströbel, P., Legler, T., Riggert, J., Hellenkamp, K., Voigt, J.U., Hasenfuß, G., Hinkel, R., Wu, J.C., Behr, R. and Zimmermann, W.H.
Nature 29 January 2025 (In Press)

Centromere positioning orchestrates telomere bouquet formation and the initiation of meiotic differentiation.
Jiménez-Martín, A., Pineda-Santaella, A., Martín-García, R., Esteban-Villafañe, R., Matarrese, A., Pinto-Cruz, J., Camacho-Cabañas, S., León-Periñán, D., Terrizzano, A., Daga, R.R., Braun, S. and Fernández-Álvarez, A.
Nature Communications 16 (1): 837. 20 January 2025

Examining the healthy human microbiome concept.
Joos, R., Boucher, K., Lavelle, A., Arumugam, M., Blaser, M.J., Claesson, M.J., Clarke, G., Cotter, P.D., De Sordi, L., Dominguez-Bello, M.G., Dutilh, B.E., Ehrlich, S.D., Ghosh, T.S., Hill, C., Junot, C., Lahti, L., Lawley, T.D., Licht, T.R., Maguin, E., Makhalanyane, T.P., Marchesi, J.R., Matthijnssens, J., Raes, J., Ravel, J., Salonen, A., Scanlan, P.D., Shkoporov, A., Stanton, C., Thiele, I., Tolstoy, I., Walter, J., Yang, B., Yutin, N., Zhernakova, A., Zwart, H., Doré, J. and Ross, R.P.
Nature Reviews Microbiology 23 (3): 192-205. March 2025

K

RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses.
Kabrani, E., Rahjouei, A., Berruezo-Llacuna, M., Ebeling, S., Saha, T., Altwasser, R., Delgado-Benito, V., Pavri, R. and Di Virgilio, M.
Nature Communications 16 (1): 777. 17 January 2025

Multicenter longitudinal quality assessment of MS-based proteomics in plasma and serum.
Kardell, O., Gronauer, T., von Toerne, C., Merl-Pham, J., König, A.C., Barth, T.K., Mergner, J., Ludwig, C., Tüshaus, J., Giesbertz, P., Breimann, S., Schweizer, L., Müller, T., Kliewer, G., Distler, U., Gomez-Zepeda, D., Popp, O., Qin, D., Teupser, D., Cox, J., Imhof, A., Küster, B., Lichtenthaler, S.F., Krijgsveld, J., Tenzer, S., Mertins, P., Coscia, F. and Hauck, S.M.
Journal of Proteome Research 7 February 2025 (In Press)

Sequential visual stimuli increase high frequency power in the visual cortex.
Keil, J., Hernandez-Urbina, V., Vassiliou, C., Dean, C., Schmitz, D., Kremkow, J. and Sibille, J.
bioRxiv : 2025.01.14.632930. 16 January 2025

Advancing optical coherence tomography diagnostic capabilities: machine learning approaches to detect autoimmune inflammatory diseases.
Kenney, R.C., Flagiello, T.A., D' Cunha, A., Alva, S., Grossman, S.N., Oertel, F.C., Paul, F., Schilling, K.G., Balcer, L.J., Galetta, S.L. and Pandit, L.
Journal of Neuro-Ophthalmology 6 February 2025 (In Press)

A novel astrocyte-neuron interaction to control complex animal behavior.
Kettenmann, H.
Neuroscience Bulletin 41 (2): 352-354. February 2025

The concept of neuroglia - the state of the art circa 1900.
Kettenmann, H., Ugursu, B., Ransom, B.R. and Steinhäuser, C.
Glia 4 February 2025 (In Press)

Blood-based biomarkers for identifying disease activity in AQP4-IgG-positive neuromyelitis optica spectrum disorder.
Kim, S.H., Gomes, A.B.A.G.R., Schindler, P., Hyun, J.W., Kim, K.H., Lee, D.E., Schoeps, V.A., Matos, A.M.B., Mendes, N.T., Apóstolos-Pereira, S.L.D., Callegaro, D., Lerner, J., Benkert, P., Kuhle, J., Ruprecht, K., Paul, F., Pröbstel, A.K. and Kim, H.J.
JAMA Neurology 82 (2): 168–175. February 2025

Quality assurance in metabolomics and metabolic profiling.
Kirwan, J.A., Bruning, U. and Mosley, J.D.
Methods in Molecular Biology 2891 : 15-51. 16 January 2025

The presence of a paramagnetic phase rim is linked to lesion age in multiple sclerosis.
Klistorner, S., Usnich, T., Clarke, M.A., Pareto, D., Rovira, A., Paul, F., Barnett, M. and Klistorner, A.
medRxiv : 2025.01.12.25320426. 13 January 2025

Hyperreflective retinal foci are associated with retinal degeneration after optic neuritis in neuromyelitis optica spectrum disorders and multiple sclerosis.
Klyscz, P., Vigiser, I., Solorza Buenrostro, G., Motamedi, S., Leutloff, C.J., Schindler, P., Schmitz-Hübsch, T., Paul, F., Zimmermann, H.G. and Oertel, F.C.
European Journal of Neurology 32 (1): e70038. January 2025

Simplified preanalytical laboratory procedures for therapeutic drug monitoring (TDM) in patients treated with high-dose methotrexate (HD-MTX) and glucarpidase.
Knörnschild, F.L., Liebig, S., Kießling, P., Prpic, M., Kim, T., Keller, U., Kappert, K., Schwartz, S. and Jahic, A.
Clinical Chemistry and Laboratory Medicine 63 (1): e11-e15. 2025

Visualization of gap junction-mediated astrocyte coupling in acute mouse brain slices.
Kompier, N.F., Siemonsmeier, G., Meyer, N., Kettenmann, H. and Rathjen, F.G.
Bio-protocol 15 : 1365. 20 February 2025

Cognitive deficits in anti-LGI1 encephalitis are linked to immunotherapy-resistant white matter network changes.
Krohn, S., Müller-Jensen, L., Kuchling, J., Romanello, A., Wurdack, K., Rekers, S., Bartsch, T., Leypoldt, F., Paul, F., Ploner, C.J., Prüss, H. and Finke, C.
Neurology Neuroimmunology & Neuroinflammation 12 (2): e200360. March 2025

Deep learning-based whole-brain B(1)(+)-mapping at 7T.
Krueger, F., Aigner, C.S., Lutz, M., Riemann, L.T., Degenhardt, K., Hadjikiriakos, K., Zimmermann, F.F., Hammernik, K., Schulz-Menger, J., Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 93 (4): 1700-1711. April 2025

A phase I study of MAGE-A1-targeted T1367 T-cell receptor-based cell therapy in patients with advanced multiple myeloma.
Krüger, J., Obenaus, M., Blau, I.W., Hoser, D., Vaegler, M., Rauschenbach, H., Anagnostopoulos, I., Jöhrens, K., Scheuplein, V., Kieback, E., Böhme, J., Von Brünneck, A.C., Krönke, J., Busse, A., Willimsky, G., Blankenstein, T., Pezzutto, A., Keller, U. and Nogai, A.
Haematologica 110 (1): 244-250. January 2025

Beyond hemoglobin: critical role of 2,3-bisphosphoglycerate mutase in kidney function and injury.
Kulow, V.A., Roegner, K., Labes, R., Kasim, M., Mathia, S., Czopek, C.S., Berndt, N., Becker, P.N., Ter-Avetisyan, G., Luft, F.C., Enghard, P., Hinze, C., Klocke, J., Eckardt, K.U., Schmidt-Ott, K.M., Persson, P.B., Rosenberger, C. and Fähling, M.
Acta Physiologica 241 (1): e14242. January 2025

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Multicenter validation of secondary hemophagocytic lymphohistiocytosis diagnostic criteria.
Lachmann, G., Heeren, P., Schuster, F.S., Nyvlt, P., Spies, C., Feinkohl, I., Schenk, T., Ammouri, W., Debaugnies, F., Galicier, L., Jia, Y., Meena, N., Nagant, C., Neth, O., Nierkens, S., San Martin, J., Sun, H.W.L., Wang, Y., Wang, Z., Yoon, J.H., Brunkhorst, F.M., La Rosée, P., Janka, G. and Lachmann, C.
Journal of Internal Medicine 27 January 2025 (In Press)

Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progression.
Laschtowitz, A., Lindberg, E.L., Liebhoff, A.M., Liebig, L.A., Casar, C., Steinmann, S., Guillot, A., Xu, J., Schwinge, D., Trauner, M., Lohse, A.W., Bonn, S., Hübner, N. and Schramm, C.
JHEP Reports 7 (3): 101267. March 2025

The proline-rich antimicrobial peptide Api137 disrupts large ribosomal subunit assembly and induces misfolding.
Lauer, S.M., Gasse, J., Krizsan, A., Reepmeyer, M., Sprink, T., Nikolay, R., Spahn, C.M.T. and Hoffmann, R.
Nature Communications 16 (1): 567. 10 January 2025

Inhalation of the novel tryptophan hydroxylase 1 inhibitor TPT-004 alleviates pulmonary arterial hypertension in rats.
Legchenko, E., Chouvarine, P., Hysko, K., Qadri, F., Wesolowski, R., Specker, E., Glage, S., Meier, M., Schwarz, K., Heineke, J., Pohlmann, G., Ramazanoglu, M., Bader, M. and Hansmann, G.
American Journal of Respiratory Cell and Molecular Biology 3 February 2025 (In Press)

Cardiac MRI strain as an early indicator of myocardial dysfunction in hypertrophic cardiomyopathy.
Liu, S., Laghzali, O., Shalikar, S., Rusu, M.C., Carrier, L., Niendorf, T. and Ku, M.C.
International Journal of Molecular Sciences 26 (4): 1407. 7 February 2025

Characterization of anthracycline-induced cardiotoxicity by diffusion tensor magnetic resonance imaging.
Lohr, D., Thiele, A., Stahnke, M., Braun, V.M., Klopfleisch, R., Klein, O., Dresen, S., Landmesser, U., Foryst-Ludwig, A., Kintscher, U., Schreiber, L.M. and Beyhoff, N.
Basic Research in Cardiology 120 (1): 57-69. February 2025

Bradykinin B1 receptor signaling triggers complement activation on endothelial cells.
Lopatko Fagerström, I., Gerogianni, A., Wendler, M., Arvidsson, I., Tontanahal, A., Kristoffersson, A.C., Qadri, F., Bader, M. and Karpman, D.
Frontiers in Immunology 16 : 1527065. 7 February 2025

Direct specification of lymphatic endothelium from mesenchymal progenitors.
Lupu, I.E., Grainger, D.E., Kirschnick, N., Weischer, S., Zhao, E., Martinez-Corral, I., Schoofs, H., Vanhollebeke, M., Jones, G., Godwin, J., Forrow, A., Lahmann, I., Riley, P.R., Zobel, T., Alitalo, K., Mäkinen, T., Kiefer, F. and Stone, O.A.
Nature Cardiovascular Research 4 (1): 45-63. January 2025

Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma.
Lutz, R., Poos, A.M., Solé-Boldo, L., John, L., Wagner, J., Prokoph, N., Baertsch, M.A., Vonficht, D., Palit, S., Brobeil, A., Mechtersheimer, G., Hildenbrand, N., Hemmer, S., Steiger, S., Horn, S., Pepke, W., Spranz, D.M., Rehnitz, C., Sant, P., Mallm, J.P., Friedrich, M.J., Reichert, P., Huhn, S., Trumpp, A., Rippe, K., Haghverdi, L., Fröhling, S., Müller-Tidow, C., Hübschmann, D., Goldschmidt, H., Willimsky, G., Sauer, S., Raab, M.S., Haas, S. and Weinhold, N.
Science Immunology 10 (104): eadp6667. February 2025

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Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.
Matera, A., Compagnion, A.C., Pedicone, C., Janssen, M.K., Ivanov, A., Monsorno, K., Labouèbe, G., Leggio, L., Pereira, M., Beule, D., Mansuy-Aubert, V., Williams, T.L., Iraci, N., Sierra, A., Marro, S.G., Goate, A.M., Eggen, B.L., Kerr, W.G. and Paolicelli, R.C.
Immunity 58 (1): 197-217. 14 January 2025

Prognostic value of CD163(+) macrophages in solid tumor malignancies: a scoping review.
Mathiesen, H., Juul-Madsen, K., Tramm, T., Vorup-Jensen, T., Møller, H.J., Etzerodt, A. and Andersen, M.N.
Immunology Letters 272 : 106970. April 2025

Production of the sesquiterpene bisabolene from one- and two-carbon compounds in engineered Methanosarcina acetivorans.
Mentrup, A., Scheitz, L.V., Wallenfang, T. and Rother, M.
Microbial Biotechnology 18 (2): e70105. February 2025

Distinguishing transient from persistent brain structural changes in pediatric patients with acute disseminated encephalomyelitis.
Millward, J.M., Pilgrim, E., Baumann, M., Wendel, E.M., El Naggar, I., Bertolini, A., Bartels, F., Finke, C., Paul, F., Niendorf, T., Rostásy, K. and Waiczies, S.
Neurology Neuroimmunology & Neuroinflammation 12 (1): e200337. January 2025

Anti-CD19 CAR T cell therapy induces antibody seroconversion and complete B cell depletion in the bone marrow of a therapy-refractory patient with ANCA-associated vasculitis.
Minopoulou, I., Wilhelm, A., Albach, F., Kleyer, A., Wiebe, E., Schallenberg, S., Fleischmann, A., Frick, M., Damm, F., Gogolok, J., Serve, S., Locher, B.N., Borie, D., Casteleyn, V., Biesen, R., Dörner, T., Alexander, T., Zernicke, J., Movassaghi, K., Hütter-Krönke, M.L., Schrezenmeier, E., Schreiber, A., Schneider, U., Bullinger, L., Krönke, G., Penack, O. and Simon, D.
Annals of the Rheumatic Diseases 31 January 2025 (In Press)

Distinct roles of cortical layer 5 subtypes in associative learning.
Moberg, S., Garibbo, M., Mazo, C., Gilad, A., Schmitz, D., Costa, R.P., Larkum, M.E. and Takahashi, N.
bioRxiv : 2025.01.07.631500. 9 January 2025

Aryl hydrocarbon receptor activation promotes effector CD4(+) T cell homeostasis and restrains salt-sensitive hypertension.
Molina, P.A., Edell, C.J., Dunaway, L.S., Kellum, C.E., Muir, R.Q., Jennings, M.S., Colson, J.C., De Miguel, C., Rhoads, M.K., Buzzelli, A.A., Harrington, L.E., Meza-Perez, S., Randall, T.D., Botta, D., Müller, D.N., Pollock, D.M., Maynard, C.L. and Pollock, J.S.
Function : zqaf001. 8 January 2025 (In Press)

Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer.
Mzoughi, S., Schwarz, M., Wang, X., Demircioglu, D., Ulukaya, G., Mohammed, K., Zorgati, H., Torre, D., Tomalin, L.E., Di Tullio, F., Company, C., Dramaretska, Y., Leushacke, M., Giotti, B., Lannagan, T.R., Lozano-Ojalvo, D., Karras, P., Vermeulen, P.B., Hasson, D., Sebra, R., Tsankov, A.M., Sansom, O.J., Marine, J.C., Barker, N., Gargiulo, G. and Guccione, E.
Nature Genetics 57 (2): 402-412. February 2025

SPINEPS-automatic whole spine segmentation of T2-weighted MR images using a two-phase approach to multi-class semantic and instance segmentation.
Möller, H., Graf, R., Schmitt, J., Keinert, B., Schön, H., Atad, M., Sekuboyina, A., Streckenbach, F., Kofler, F., Kroencke, T., Bette, S., Willich, S.N., Keil, T., Niendorf, T., Pischon, T., Endemann, B., Menze, B., Rueckert, D. and Kirschke, J.S.
European Radiology 35 (3): 1178-1189. March 2025

Gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice.
Mühlgrabner, V., Plach, A., Holler, J., Leitner, J., Steinberger, P., Dupré, L., Göhring, J. and Huppa, J.B.
Methods in Cell Biology 193 : 127-154. 5 February 2025

Engineering therapeutic regulatory T cells to overexpress G protein-coupled receptor 15 improves functional fitness for in vivo gut homing.
Müller, T.M., Liu, L.J., Wiesinger, M., Neurath, M.F., Voskens, C.J. and Zundler, S.
Gastroenterology 168 (2): 389-392. February 2025

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Socioeconomic characteristics and the home food environment are associated with feeding healthful and discretionary foods during the first year of life in the Pregnancy Eating Attributes Study.
Nansel, T.R., Lipsky, L.M., Schwedhelm, C., Faith, M.S. and Siega-Riz, A.M.
Journal of the Academy of Nutrition and Dietetics 125 (2): 228-238. February 2025

Herpesviruses mimic zygotic genome activation to promote viral replication.
Neugebauer, E., Walter, S., Tan, J., Drayman, N., Franke, V., van Gent, M., Pennisi, S., Veratti, P., Stein, K.S., Welker, I., Tay, S., Verjans, G.M.G.M., Timmers, H.T.M., Akalin, A., Landthaler, M., Ensser, A., Wyler, E. and Full, F.
Nature Communications 16 (1): 710. 16 January 2025

Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations.
Nishijima, S., Stankevic, E., Aasmets, O., Schmidt, T.S.B., Nagata, N., Keller, M.I., Ferretti, P., Juel, H.B., Fullam, A., Robbani, S.M., Schudoma, C., Hansen, J.K., Holm, L.A., Israelsen, M., Schierwagen, R., Torp, N., Telzerow, A., Hercog, R., Kandels, S., Hazenbrink, D.H.M., Arumugam, M., Bendtsen, F., Brøns, C., Fonvig, C.E., Holm, J.C., Nielsen, T., Pedersen, J.S., Thiele, M.S., Trebicka, J., Org, E., Krag, A., Hansen, T., Kuhn, M. and Bork, P.
Cell 188 (1): 222-236. 9 January 2025

3D metamaterials facilitate human cardiac MRI at 21.0 Tesla: a proof-of-concept study.
Nurzed, B., Saha, N., Millward, J.M. and Niendorf, T.
Sensors 25 (3): 620. 21 January 2025

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Divergent endothelial mechanisms drive arteriovenous malformations in ALK1 and SMAD4 loss-of-function.
Oppenheim, O., Giese, W., Park, H., Baumann, E., Ivanov, A., Beule, D., Eichmann, A. and Gerhardt, H.
bioRxiv : 2025.01.03.631070v2. 6 January 2025

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Pharmacological characterisation of a clinical candidate, TG-0054, a small molecule inverse agonist targeting CXCR4.
Pan, K.S., Wang, Z., Pfeil, C., Bergkamp, N.D., Mobach, S., Roth, S., Rizk, A., Lohse, M.J., Annibale, P., Siderius, M., Zimmermann, M., Smit, M.J. and Bosma, R.
Molecular Pharmacology : 100015. 31 January 2025 (In Press)

Immunomodulatory potential of a bibenzyl-dihydrophenanthrene derivative isolated from Calanthe cardioglossa.
Pengdee, C., Dehlinger, A., Chaichompoo, W., Kongkatitham, V., Chaotham, C., Rojsitthisak, P., Böttcher, C. and Sritularak, B.
Journal of Natural Products 29 January 2025 (In Press)

Challenges and opportunities in the clinical translation of high-resolution spatial transcriptomics.
Pentimalli, T.M., Karaiskos, N. and Rajewsky, N.
Annual Review of Pathology : Mechanisms of Disease 20 : 405-432. January 2025

Stellungnahme und gemeinsame Position der Jungen Neurologie, der Deutschen Gesellschaft für Neurologie e.V. (DGN) und der Deutschen Gesellschaft für NeuroIntensiv- und Notfallmedizin e.V. (DGNI) zum Positionspapier der DIVI und Jungen DIVI [Statement and joint position of the “Young Neurology”, German Society for Neurology (DGN) e.V. and the German Society for NeuroIntensive and Emergency Medicine (DGNI) e.V. on the position paper of the DIVI and Young DIVI].
Piel, J.H.A., Biesalski, A.S., Oertel, F.C., Bösel, J., Brandt, S., Schramm, P., Niesen, W.D., Salih, F., Westermaier, T., Berg, D. and Timmermann, L.
Deutsche Medizinische Wochenschrift 150 (03): 114-115. January 2025

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Multimodal longitudinal optical imaging reveals optic neuritis preceding retinal pathology in experimental autoimmune encephalomyelitis.
Raspe, R., Günther, R., Uecker, R., Rakhymzhan, A., Paul, F., Radbruch, H., Niesner, R.A. and Hauser, A.E.
Neurology Neuroimmunology & Neuroinflammation 12 (1): e200338. January 2025

Metrics matter: why we need to stop using silhouette in single-cell benchmarking.
Rautenstrauch, P. and Ohler, U.
bioRxiv : 2025.01.21.634098. 24 January 2025

Barriers in healthcare to the use of optical coherence tomography angiography in multiple sclerosis.
Reeß, L.G., Salih, H., Delikaya, M., Paul, F. and Oertel, F.C.
Neurology and Therapy 14 (1): 45-56. February 2025

Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort.
Reichmann, R., Nimptsch, K., Pischon, T., Gunter, M.J., Jenab, M., Eriksen, A.K., Tjonneland, A., Janke, J., Katzke, V., Kaaks, R., Schulze, M.B., Eichelmann, F., Masala, G., Sieri, S., Pasanisi, F., Tumino, R., Giraudo, M.T., Rothwell, J., Severi, G., Jakszyn, P., Sanchez-Perez, M.J., Amiano, P., Colorado-Yohar, S.M., Guevara, M., van Guelpen, B., Aglago, E.K., Heath, A.K., Smith-Byrne, K., Weiderpass, E. and Aleksandrova, K.
International Journal of Cancer 156 (5): 930-942. 1 March 2025

Sleep and circadian rhythms in delayed sleep-wake phase disorder: phenotypic differences between patients with and without comorbid depression.
Reis, C., Pilz, L.K., Paiva, T., Hidalgo, M.P. and Wright, K.P.
Journal of Sleep Research : e14437. 15 January 2025 (In Press)

Renal damage-induced hepcidin accumulation contributes to anemia in angiotensinogen-deficient mice.
Rodrigues, A.F., Boreggio, L., Lahuta, T., Qadri, F., Alenina, N., Barros, C.C., Todiras, M. and Bader, M.
Clinical Science 139 (3): 247-258. February 2025

Characterizing uveal melanoma patients with peritoneal metastases: a retrospective single-center analysis.
Rosnev, S., Peuker, C.A., Piwonski, I., Ihlow, J., Leyvraz, S., Klingberg, J., Horst, D., Joosten, M., Möbs, M., Joussen, A.M., de Bucourt, M., Keilholz, U., Keller, U., Ochsenreither, S. and Rittig, S.M.
European Journal of Cancer 218 : 115280. March 2025 (In Press)

Reduced monocytic IL10 expression in PD1 inhibitor-treated patients is a harbinger of severe immune-related adverse events.
Rosnev, S., Sterner, B., Schiele, P., Kolling, S., Martin, M., Flörcken, A., Erber, B., Wittenbecher, F., Kofla, G., Kurreck, A., Lang, T.J.L., von Einem, J.C., de Santis, M., Pelzer, U., Stintzing, S., Bullinger, L., Klinghammer, K., Geisel, D., Ochsenreither, S., Frentsch, M. and Na, I.K.
European Journal of Cancer 217 : 115252. 25 February 2025

The non-canonical proteome: a novel contributor to cancer proliferation.
Ruiz-Orera, J. and Hübner, N.
Cell Research 14 January 2025 (In Press)

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Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics.
Sakenova, N., Cacace, E., Orakov, A., Huber, F., Varik, V., Kritikos, G., Michiels, J., Bork, P., Cossart, P., Goemans, C.V. and Typas, A.
Nature Microbiology 10 (1): 202-216. January 2025

The next generation of in situ multi-omics.
Salla, M., Penkert, K. and Ludwig, L.S.
Nature Methods 27 January 2025 (In Press)

The role of Neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) in MS and AQP4-NMOSD: advancing clinical applications.
Samadzadeh, S. and Sleator, R.D.
eNeurologicalSci 38 : 100550. March 2025

Dental and oral health assessments in the German National Cohort (NAKO).
Samietz, S., Borof, K., Hertrampf, K., Aarabi, G., Ciardo, A., Finke, H., Hagenfeld, D., Kühnisch, J., Rütters, M., Baumeister, S.E., Reckelkamm, S.L., Kim, T.S., Kocher, T., Ahrens, W., Brenner, H., Emmel, C., Fischer, B., Führer, A., Greiser, K.H., Grischke, J., Günther, K., Harth, V., Jaskulski, S., Karch, A., Keil, T., Kemmling, Y., Kluttig, A., Krist, L., Kuss, O., Leitzmann, M., Meinke-Franze, C., Michels, K.B., Obi, N., Peters, A., Pischon, N., Pischon, T., Schipf, S., Schmidt, B., Teismann, H., Rupf, S. and Holtfreter, B.
BMC Oral Health 25 (1): 149. 28 January 2025

Persistence and/or senescence: not so lasting at last?
Schmitt, C.A.
Cancer Research 85 (1): 7-9. 2 January 2025

Linking higher amyloid beta 1-38 (Aβ(1-38)) levels to reduced Alzheimer's disease progression risk.
Schneider, L.S., Freiesleben, S.D., van Breukelen, G., Wang, X., Brosseron, F., Heneka, M.T., Teipel, S., Kleineidam, L., Stark, M., Roy-Kluth, N., Wagner, M., Spottke, A., Schmid, M., Roeske, S., Laske, C., Munk, M.H., Perneczky, R., Rauchmann, B.S., Buerger, K., Janowitz, D., Düzel, E., Glanz, W., Jessen, F., Rostamzadeh, A., Wiltfang, J., Bartels, C., Kilimann, I., Schneider, A., Fliessbach, K., Priller, J., Spruth, E.J., Hellmann-Regen, J. and Peters, O.
Alzheimer's & Dementia : e14545. 27 January 2025 (In Press)

Protocol for high-resolution 3D spatial transcriptomics using Open-ST.
Schott, M., León-Periñán, D., Splendiani, E., Ferretti, E., Macino, G., Karaiskos, N. and Rajewsky, N.
STAR Protocols 6 (1): 103521. 21 March 2025

Ultrasound pupillometry for the detection of a relative afferent pupillary defect (RAPD): systematic evaluation in patients with optic neuritis and comparison with infrared video pupillometry.
Siebald, F., Grittner, U., Otto, C., Bereuter, C., Zimmermann, H.G., Harms, L., Klonner, J., Schreiber, S.J., Paul, F., Ruprecht, K. and Schmidt, F.A.
PLoS ONE 20 (1): e0315712. 10 January 2025

Phosphoproteomics for studying signaling pathways evoked by hormones of the renin-angiotensin system: a source of untapped potential.
Souza-Silva, I.M., Carregari, V.C., Steckelings, U.M. and Verano-Braga, T.
Acta Physiologica 241 (2): e14280. February 2025

LINNAEUS: simultaneous single-cell lineage tracing and cell type identification.
Spanjaard, B. and Junker, J.P.
Methods in Molecular Biology 2886 : 243-263. 3 January 2025

Lessons from a negative gene therapy trial for Duchenne muscular dystrophy.
Spuler, S., Borasio, G.D. and Grittner, U.
Nature Medicine 31 (1): 37-38. January 2025

Gene-environment interaction analysis in atopic eczema: evidence from large population datasets and modelling in vitro.
Standl, M., Budu-Aggrey, A., Johnston, L.J., Elias, M.S., Arshad, S.H., Bager, P., Bataille, V., Blakeway, H., Bonnelykke, K., Boomsma, D., Brumpton, B.M., Pineda, M.B., Campbell, A., Curtin, J.A., Eliasen, A., Fadista, J.P.S., Feenstra, B., Gerner, T., Gomez, C.M., Grosche, S., Gutzkow, K.B., Halling, A.S., Hayward, C., Henderson, J., Herrera-Luis, E., Holloway, J.W., Hottenga, J., O'B Hourihane, J., Hu, C., Hveem, K., Irizar, A., Jacquemi, B., Jessen, L., Kress, S., Kurukulaaratchy, R.J., Lau, S., Llop, S., Løset, M., Marenholtz, I., Mason, D., McCartney, D.L., Melbye, M., Melén, E., Minica, C., Murray, C.S., Nijsten, T., Pardo, L.M., Pasmans, S., Pennell, C.E., Rinnov, M.R., Santorelli, G., Schikowski, T., Sheehan, D., Simpson, A., Söderhäll, C., Thomas, L.F., Thyssen, J.P., Torrent, M., van Beijsterveldt, T., Visconti, A., Vonk, J.M., Wang, C.A., Xu, C.J., Ziyab, A.H., Custovic, A., Meglio, P.D., Duijts, L., Flohr, C., Irvine, A.D., Koppelman, G.H., Lee, Y.A., Reynolds, N.J., Smith, C., Langan, S.M., Paternoster, L. and Brown, S.J.
medRxiv : 2025.01.24.2532107. 28 January 2025

Efficacy of repeated immunoadsorption in patients with post-COVID myalgic encephalomyelitis/chronic fatigue syndrome and elevated β2-adrenergic receptor autoantibodies: a prospective cohort study.
Stein, E., Heindrich, C., Wittke, K., Kedor, C., Rust, R., Freitag, H., Sotzny, F., Krüger, A., Tölle, M., Grabowski, P., Scheibenbogen, C. and Kim, L.
Lancet Regional Health - Europe 49 : 101161. February 2025

Cryosectioning-enhanced super-resolution microscopy for single-protein imaging across cells and tissues.
Stein, J., Ericsson, M., Nofal, M., Magni, L., Aufmkolk, S., McMillan, R.B., Breimann, L., Herlihy, C.P., Lee, S.D., Willemin, A., Wohlmann, J., Arguedas-Jimenez, L., Yin, P., Pombo, A., Church, G.M. and Wu, C.T.
bioRxiv : 2024.02.05.576943v2. 13 February 2025

Diurnal timing of physical activity in relation to obesity and diabetes in the German National Cohort (NAKO).
Stein, M.J., Weber, A., Bamberg, F., Baurecht, H., Berger, K., Bohmann, P., Brenner, H., Brummer, J., Dörr, M., Fischer, B., Gastell, S., Greiser, K.H., Harth, V., Hebestreit, A., Heise, J.K., Herbolsheimer, F., Ittermann, T., Karch, A., Keil, T., Kluttig, A., Krist, L., Michels, K.B., Mikolajczyk, R., Nauck, M., Nimptsch, K., Obi, N., Pischon, T., Pivovarova-Ramich, O., Schikowski, T., Schmidt, B., Schulze, M.B., Steindorf, K., Zylla, S. and Leitzmann, M.F
International Journal of Obesity 24 January 2025 (In Press)

OCT-based retina assessment reflects visual impairment in multiple sclerosis.
Stolowy, N., Gutmann, L., Lüpke, M., David, T., Dorr, M., Mayer, C., Heesen, C., Oertel, F.C., Lin, T.Y., Paul, F., Zimmermann, H.G. and Stellmann, J.P.
Investigative Ophthalmology & Visual Science 66 (2): 39. February 2025

Therapy adherence after interdisciplinary tumour board discussion is associated with improved outcome in soft tissue sarcoma: a Charité Comprehensive Cancer Centre analysis.
Strönisch, A., Rau, D., Wittenberg, S., Kaul, D., Koulaxouzidis, G., Öllinger, R., von Laffert, M., Jarosch, A., Schäfer, F., Keilholz, U., Bullinger, L., Märdian, S., Striefler, J. and Flörcken, A.
International Journal of Cancer 156 (4): 802-816. 15 February 2025

Expression and function of Connexin 43 and Connexin 37 in the murine zona glomerulosa.
Stölting, G., Hellmig, N., Dinh, H.A., Butz, F., Secener, A.K., Volkert, M. and Scholl, U.I.
Physiological Reports 13 (3): e70215. February 2025

Outer retina micro-inflammation is driven by T cell responses prior to retinal degeneration in early age-related macular degeneration.
Stürzbecher, L., Bartolomaeus, H., Bartolomaeus, T.U.P., Bolz, S., Sekulic, A., Ueffing, M., Clark, S.J., Reichhart, N., Crespo-Garcia, S., Wilck, N. and Strauß, O.
Frontiers in Immunology 16 : 1520188. 5 February 2025

Associations of the adaptive immune system and age-related macular degeneration.
Stürzbecher, L. and Strauss, O.
In: International Workshop on Ambient Assisted Living - IWAAL 2011, 08-11 Jun 2011, Torremolinos, Spain. 11 February 2025

Brain lesion characteristics in Chinese multiple sclerosis patients: a 7-T MRI cohort study.
Su, L., Zhang, Z., Gao, C., Guo, A., Zhang, M., Shi, X., Liu, X., Song, T., Xu, W., Wang, H., Kuchling, J., Jing, J., Tian, D.C., Liu, Y., Duan, Y., Paul, F. and Shi, F.D.
Annals of Clinical and Translational Neurology 12 (2): 300-310. February 2025

hnRNPA2B1 drives colorectal cancer progression via the circCDYL/EIF4A3/PHF8 axis.
Sun, Y.K., Wang, J.F., Sun, X.W. and Zhang, M.
Kaohsiung Journal of Medical Sciences : e12943. 15 January 2025 (In Press)

The STRING database in 2025: protein networks with directionality of regulation.
Szklarczyk, D., Nastou, K., Koutrouli, M., Kirsch, R., Mehryary, F., Hachilif, R., Hu, D., Peluso, M.E., Huang, Q., Fang, T., Doncheva, N.T., Pyysalo, S., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 53 (D1): D730–D737. 6 January 2025

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A novel approach to modelling acute cardiac decompensation in rats.
Thiele, A., Bartolomaeus, H., Anandakumar, H., Haase, N., Heuser, A., Müller, D.N., Dechend, R. and Wilck, N.
Cardiovascular Research : cvae268. 6 January 2025 (In Press)

Machine learning models for the early real-time prediction of deterioration in intensive care units: a novel approach to the early identification of high-risk patients.
Thiele, D., Rodseth, R., Friedland, R., Berger, F., Mathew, C., Maslo, C., Moll, V., Leithner, C., Storm, C., Krannich, A. and Nee, J.
Journal of Clinical Medicine 14 (2): 350. January 2025

Identification of V0g propriospinal neurons and their role in locomotor control.
Toscano, E., Giomi, M., Evtushenko, N., Santuz, A., Lowenstein, E.D., Birchmeier, C. and Zampieri, N.
bioRxiv : 2025.02.11.636221. 12 February 2025

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Effect of siponimod on retinal thickness, a marker of neurodegeneration, in participants with SPMS: Findings from the EXPAND OCT substudy.
Vermersch, P., Gold, R., Bar-Or, A., Cree, B.A.C., Fox, R.J., Giovannoni, G., Paul, F., Wolf, S., Li, B., Mousseau, M.C., Maio-Twofoot, T., Shi, X. and Kappos, L.
Multiple Sclerosis and Related Disorders 94 : 106259. February 2025

Acute promyelocytic leukemia: long-term outcomes from the HARMONY project.
Voso, M.T., Guarnera, L., Lehmann, S., Döhner, K., Döhner, H., Platzbecker, U., Russell, N.H., Dillon, R.J., Thomas, I., Ossenkoppele, G.J., Haferlach, T., Vignetti, M., La Sala, E., Piciocchi, A., Fazi, P., Villaverde Ramiro, Á., Tur Giménez, L., Gurnari, C., Bullinger, L. and Hernandez, J.M.
Blood 145 (2): 234-243. 9 January 2025

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The IsletTester mouse: an immunodeficient model with stable hyperglycemia for the study of human islets.
Waite, E.L., Tigue, M., Yu, M., Lahori, D., Kelly, K., May, C.L., Naji, A., Roman, J., Doliba, N., Avrahami, D., Nguyen-Ngoc, K.V., Sander, M., Glaser, B. and Kaestner, K.H.
Diabetes 74 (3): 332-342. March 2025

Cytokine-armed vaccinia virus promotes cytotoxicity toward pancreatic carcinoma cells via activation of human intermediary CD56(dim)CD16(dim) natural killer cells.
Wang, R., Hu, M., Lozzi, I., Jin, C.Z.J., Ma, D., Splith, K., Mengwasser, J., Wolf, V., Feldbrügge, L., Tang, P., Timmermann, L., Hillebrandt, K.H., Kirchner, M., Mertins, P., Hilfenhaus, G., Neumann, C.C.M., Kammertoens, T., Pratschke, J., Malinka, T., Sauer, I.M., Noessner, E., Guo, Z.S. and Felsenstein, M.
International Journal of Cancer 156 (3): 638-651. 1 February 2025

Clinical characteristics and outcomes in leptomeningeal disease with or without brain metastasis: insights from an explorative data analysis of the Charité LMD registry.
Wasilewski, D., Eitner, C., Ates, R., Murad, S., Shaked, Z., Steinle, J.A., Wetzel-Yalelis, A., Sargut, T.A., Rösler, J., Samman, M.A., Truckenmüller, P., Mertens, R., Kroneberg, D., Kowski, A., Radbruch, H., Capper, D., Ehret, F., Roohani, S., Frost, N., Nawabi, J., Onken, J., Schlaak, M., Blohmer, J.U., Pelzer, U., Keller, U., Sehouli, J., Vajkoczy, P., Keilholz, U. and Misch, M.
Journal of Neuro-Oncology 11 February 2025 (In Press)

TERT expression and clinical outcome in pulmonary carcinoids.
Werr, L., Bartenhagen, C., Rosswog, C., Cartolano, M., Voegele, C., Sexton-Oates, A., Di Genova, A., Ernst, A., Kahlert, Y., Hemstedt, N., Höppner, S., Mansuet Lupo, A., Pelosi, G., Brcic, L., Papotti, M., George, J., Bosco, G., Quaas, A., Tang, L.H., Robzyk, K., Kadota, K., Roh, M.S., Fanaroff, R.E., Falcon, C.J., Büttner, R., Lantuejoul, S., Rekhtman, N., Rudin, C.M., Travis, W.D., Alcala, N., Fernandez-Cuesta, L., Foll, M., Peifer, M., Thomas, R.K. and Fischer, M.
Journal of Clinical Oncology 43 (2): 214-225. 10 January 2025

Visualizing the modification landscape of the human 60S ribosomal subunit at close to atomic resolution.
Wiechert, F., Unbehaun, A., Sprink, T., Seibel, H., Bürger, J., Loerke, J., Mielke, T., Diebolder, C.A., Schacherl, M. and Spahn, C.M.T.
Nucleic Acids Research 53 (1): gkae1191. 13 January 2025

Complex human hair bearing skin organoids as model for herpes simplex virus 1 infection in the skin.
Wyler, E., Albertini, S., Friedel, C.C., Manukyan, A., Huang, J., Krasemann, S., Plumbon, I., Altmüller, J., Conrad, T., Radbruch, H., Hafezi, W., Hansen, A., Grundhoff, A., Landthaler, M., Fischer, N. and Czech-Sioli, M.
bioRxiv : 2025.02.10.637415. 11 February 2025

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Effects of a 6-week treadmill training with and without virtual reality on frailty in people with multiple sclerosis: Frailty rehabilitation in multiple sclerosis.
Zanotto, T., Galperin, I., Kumar, D.P., Mirelman, A., Yehezkyahu, S., Regev, K., Karni, A., Schmitz-Hübsch, T., Paul, F., Lynch, S.G., Akinwuntan, A.E., He, J., Troen, B.R., Devos, H., Hausdorff, J.M. and Sosnoff, J.J.
Archives of Physical Medicine and Rehabilitation 106 (2): 187-194. February 2025

Protein kinase A regulates ferroptosis by controlling GPX4 m(6)A modification through phosphorylation of ALKBH5.
Zhao, X., Sun, Y., Zou, J., Wu, Y., Huang, M., Kong, H., Liu, G., Gerhardt, H., Gu, W., Zhang, Y., Shang, M. and Wang, X.
Cell Death and Differentiation 3 February 2025 (In Press)

Everolimus with or without mycophenolate mofetil for GVHD prophylaxis after allogeneic HSCT in children with acute kidney injury - a single-center retrospective analysis.
Zirngibl, F., Gebert, P., Materne, B., Launspach, M., Künkele, A., Hundsdoerfer, P., Cyrull, S., Deubzer, H.E., Kühl, J.S., Eggert, A., Lang, P., Oevermann, L., von Stackelberg, A. and Schulte, J.H.
Transplantation and Cellular Therapy 7 January 2025 (In Press)

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Transgenic rat with ubiquitous expression of angiotensin-(1-7)-producing fusion protein: a new tool to study the role of protective arm of the renin-angiotensin system in the pathophysiology of cardio-renal diseases.
Červenka, L., Husková, Z., Kikerlová, S., Gawrys, O., Vacková, Š., Škaroupková, P., Sadowski, J., Miklovič, M., Molnár, M., Táborský, M., Melenovský, V. and Bader, M.
Hypertension Research 48 (1): 336-352. January 2025