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Article

Computational pan-genomics: status, promises and challenges.

Briefings in Bioinformatics 19 (1): 118-135. January 2018

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Lancet 392 (10159): 1923-1994. 2018

A mechanistic classification of clinical phenotypes in neuroblastoma.
Ackermann, S., Cartolano, M., Hero, B., Welte, A., Kahlert, Y., Roderwieser, A., Bartenhagen, C., Walter, E., Gecht, J., Kerschke, L., Volland, R., Menon, R., Heuckmann, J.M., Gartlgruber, M., Hartlieb, S., Henrich, K.O., Okonechnikov, K., Altmüller, J., Nürnberg, P., Lefever, S., de Wilde, B., Sand, F., Ikram, F., Rosswog, C., Fischer, J., Theissen, J., Hertwig, F., Singhi, A.D., Simon, T., Vogel, W., Perner, S., Krug, B., Schmidt, M., Rahmann, S., Achter, V., Lang, U., Vokuhl, C., Ortmann, M., Büttner, R., Eggert, A., Speleman, F., O'Sullivan, R.J., Thomas, R.K., Berthold, F., Vandesompele, J., Schramm, A., Westermann, F., Schulte, J.H., Peifer, M. and Fischer, M.
Science 362 (6419): 1165-1170. 7 December 2018

The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.
Althof, N., Goetzke, C.C., Kespohl, M., Voss, K., Heuser, A., Pinkert, S., Kaya, Z., Klingel, K. and Beling, A.
EMBO Molecular Medicine 10 (2): 200-218. 1 February 2018

Polarity acquisition in cortical neurons is driven by synergistic action of Sox9-regulated Wwp1 and Wwp2 E3 ubiquitin ligases and intronic miR-140.
Ambrozkiewicz, M.C., Schwark, M., Kishimoto-Suga, M., Borisova, E., Hori, K., Salazar-Lázaro, A., Rusanova, A., Altas, B., Piepkorn, L., Bessa, P., Schaub, T., Zhang, X., Rabe, T., Ripamonti, S., Rosário, M., Akiyama, H., Jahn, O., Kobayashi, T., Hoshino, M., Tarabykin, V. and Kawabe, H.
Neuron 100 (5): 1097-1115. 5 December 2018

Related GPCRs couple differently to G(s): preassociation between G protein and 5-HT(7) serotonin receptor reveals movement of Gα(s) upon receptor activation.
Andressen, K.W., Ulsund, A.H., Krobert, K.A., Lohse, M.J., Buenemann, M. and Levy, F.O.
FASEB Journal 32 (2): 1059-1069. 5 February 2018

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Angulo-Urarte, A., Casado, P., Castillo, S.D., Kobialka, P., Kotini, M.P., Figueiredo, A.M., Castel, P., Rajeeve, V., Milà-Guasch, M., Millan, J., Wiesner, C., Serra, H., Muixi, L., Casanovas, O., Viñals, F., Affolter, M., Gerhardt, H., Huveneers, S., Belting, H.G., Cutillas, P.R. and Graupera, M.
Nature Communications 9 (1): 4826. 16 November 2018

Molecular Dynamics simulations of the Strings and Binders Switch Model of chromatin.
Annunziatella, C., Chiariello, A.M., Esposito, A., Bianco, S., Fiorillo, L. and Nicodemi, M.
Methods 142 : 81-88. 1 June 2018

Proteomics, post-translational modifications, and integrative analyses reveal molecular heterogeneity within medulloblastoma subgroups.
Archer, T.C., Ehrenberger, T., Mundt, F., Gold, M.P., Krug, K., Mah, C.K., Mahoney, E.L., Daniel, C.J., LeNail, A., Ramamoorthy, D., Mertins, P., Mani, D.R., Zhang, H., Gillette, M.A., Clauser, K., Noble, M., Tang, L.C., Pierre-François, J., Silterra, J., Jensen, J., Tamayo, P., Korshunov, A., Pfister, S.M., Kool, M., Northcott, P.A., Sears, R.C., Lipton, J.O., Carr, S.A., Mesirov, J.P., Pomeroy, S.L. and Fraenkel, E.
Cancer Cell 34 (3): 396-410. 10 September 2018

Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.
Arends, C.M., Galan-Sousa, J., Hoyer, K., Chan, W., Jäger, M., Yoshida, K., Seemann, R., Noerenberg, D., Waldhueter, N., Fleischer-Notter, H., Christen, F., Schmitt, C.A., Dörken, B., Pelzer, U., Sinn, M., Zemojtel, T., Ogawa, S., Märdian, S., Schreiber, A., Kunitz, A., Krüger, U., Bullinger, L., Mylonas, E., Frick, M. and Damm, F.
Leukemia 32 (9): 1908-1919. September 2018

Allosteric inhibition of a mammalian lectin.
Aretz, J., Anumala, U.R., Fuchsberger, F.F., Molavi, N., Ziebart, N., Zhang, H., Nazaré, M. and Rademacher, C.
Journal of the American Chemical Society 140 (44): 14915-14925. 7 November 2018

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K., Kranz, A., Fohgrub, J., Jolly, A., Bledau, A.S., Di Virgilio, M., Lesche, M., Dahl, A., Höfer, T., Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018

Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.
Arnhold, V., Schmelz, K., Proba, J., Winkler, A., Wünschel, J., Toedling, J., Deubzer, H.E., Künkele, A., Eggert, A., Schulte, J.H. and Hundsdoerfer, P.
Oncotarget 9 (2): 2304-2319. 2018

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.
Arnoux, I., Willam, M., Griesche, N., Krummeich, J., Watari, H., Offermann, N., Weber, S., Narayan Dey, P., Chen, C., Monteiro, O., Buettner, S., Meyer, K., Bano, D., Radyushkin, K., Langston, R., Lambert, J.J., Wanker, E., Methner, A., Krauss, S., Schweiger, S. and Stroh, A.
eLife 7 : e38744. 4 September 2018

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.
Asai, Y., Eslami, A., van Ginkel, C.D., Akhabir, L., Wan, M., Yin, D., Ellis, G., Ben-Shoshan, M., Marenholz, I., Martino, D., Ferreira, M.A., Allen, K., Mazer, B., de Groot, H., de Jong, N.W., Gerth van Wijk, R., Dubois, A.E.J., Grosche, S., Ashley, S., Rüschendorf, F., Kalb, B., Beyer, K., Nöthen, M.M., Lee, Y.A., Chin, R., Cheuk, S., Hoffman, J., Jorgensen, E., Witte, J.S., Melles, R.B., Hong, X., Wang, X., Hui, J., Musk, A.W.B., Hunter, M., James, A.L., Koppelman, G.H., Sandford, A.J., Clarke, A.E. and Daley, D.
Journal of Allergy and Clinical Immunology 141 (4): 1513-1516. April 2018

Candidate gene testing in clinical cohort studies with multiplexed genotyping and mass spectrometry.
Ashley, S.E., Meyer, B.A., Ellis, J.A. and Martino, D.J.
Journal of Visualized Experiments (136): e57601. 21 June 2018

Pain in AQP4-IgG-positive and MOG-IgG-positive neuromyelitis optica spectrum disorders.
Asseyer, S., Schmidt, F., Chien, C., Scheel, M., Ruprecht, K., Bellmann-Strobl, J., Brandt, A.U. and Paul, F.
Multiple Sclerosis Journal Experimental Translational and Clinical 4 (3): 2055217318796684. 1 July 2018

mHTT seeding activity: a marker of disease progression and neurotoxicity in models of Huntington's disease.
Ast, A., Buntru, A., Schindler, F., Hasenkopf, R., Schulz, A., Brusendorf, L., Klockmeier, K., Grelle, G., McMahon, B., Niederlechner, H., Jansen, I., Diez, L., Edel, J., Boeddrich, A., Franklin, S.A., Baldo, B., Schnoegl, S., Kunz, S., Purfürst, B., Gaertner, A., Kampinga, H.H., Morton, A.J., Petersén, Å., Kirstein, J., Bates, G.P. and Wanker, E.E.
Molecular Cell 71 (5): 675-688. 6 September 2018

A filter retardation assay facilitates the detection and quantification of heat-stable, amyloidogenic mutant huntingtin aggregates in complex biosamples.
Ast, A., Schindler, F., Buntru, A., Schnoegl, S. and Wanker, E.E.
Methods in Molecular Biology 1780 : 31-40. 2018

Temporal visual resolution and disease severity in MS.
Ayadi, N., Dörr, J., Motamedi, S., Gawlik, K., Bellmann-Strobl, J., Mikolajczak, J., Brandt, A.U., Zimmermann, H. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 5 (5): e492. 1 September 2018

Anatomical wiring and functional networking changes in the visual system following optic neuritis.
Backner, Y., Kuchling, J., Massarwa, S., Oberwahrenbrock, T., Finke, C., Bellmann-Strobl, J., Ruprecht, K., Brandt, A.U., Zimmermann, H., Raz, N., Paul, F. and Levin, N.
JAMA Neurology 75 (3): 287-295. March 2018

Newly designed 16S rRNA metabarcoding primers amplify diverse and novel archaeal taxa from the environment.
Bahram, M., Anslan, S., Hildebrand, F., Bork, P. and Tedersoo, L.
Environmental Microbiology Reports 11 (4): 487-494. August 2018

Structure and function of the global topsoil microbiome.
Bahram, M., Hildebrand, F., Forslund, S.K., Anderson, J.L., Soudzilovskaia, N.A., Bodegom, P.M., Bengtsson-Palme, J., Anslan, S., Coelho, L.P., Harend, H., Huerta-Cepas, J., Medema, M.H., Maltz, M.R., Mundra, S., Olsson, P.A., Pent, M., Põlme, S., Sunagawa, S., Ryberg, M., Tedersoo, L. and Bork, P.
Nature 560 (7717): 233-237. 9 August 2018

The International Multiple Sclerosis Visual System Consortium: advancing visual system research in multiple sclerosis.
Balcer, L.J., Balk, L.J., Brandt, A.U., Calabresi, P.A., Martinez-Lapiscina, E.H., Nolan, R.C., Paul, F., Petzold, A. and Saidha, S.
Journal of Neuro-Ophthalmology 38 (4): 494-501. December 2018

ProTox-II: a webserver for the prediction of toxicity of chemicals.
Banerjee, P., Eckert, A.O., Schrey, A.K. and Preissner, R.
Nucleic Acids Research 46 (W1): W257-W263. 2 July 2018

BitterSweetForest: a Random Forest based binary classifier to predict bitterness and sweetness of chemical compounds.
Banerjee, P. and Preissner, R.
Frontiers in Chemistry 6 : 93. April 2018

Role of VTA dopamine neurons and neuroligin 3 in sociability traits related to nonfamiliar conspecific interaction.
Bariselli, S., Hörnberg, H., Prévost-Solié, C., Musardo, S., Hatstatt-Burklé, L., Scheiffele, P. and Bellone, C.
Nature Communications 9 (1): 3173. 9 August 2018

Chronic overexpression of bradykinin in kidney causes polyuria and cardiac hypertrophy.
Barros, C.C., Schadock, I., Sihn, G., Rother, F., Xu, P., Popova, E., Lapidus, I., Plehm, R., Heuser, A., Todiras, M., Bachmann, S., Alenina, N., Araujo, R.C., Pesquero, J.B. and Bader, M.
Frontiers in Medicine 5 : 338. December 2018

All-optical microscope autofocus based on an electrically tunable lens and a totally internally reflected IR laser.
Bathe-Peters, M., Annibale, P. and Lohse, M.J.
Optics Express 26 (3): 2359-2368. 5 February 2018

Pervasive protein thermal stability variation during the cell cycle.
Becher, I., Andrés-Pons, A., Romanov, N., Stein, F., Schramm, M., Baudin, F., Helm, D., Kurzawa, N., Mateus, A., Mackmull, M.T., Typas, A., Müller, C.W., Bork, P., Beck, M. and Savitski, M.M.
Cell 173 (6): 1495-1507. 31 May 2018

In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI.
Becker, K.M., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Current Directions in Biomedical Engineering 4 (1): 263-266. 1 September 2018

7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions.
Behrens, J.R., Wanner, J., Kuchling, J., Ostendorf, L., Harms, L., Ruprecht, K., Niendorf, T., Jarius, S., Wildemann, B., Gieß, R.M., Scheel, M., Bellmann-Strobl, J., Wuerfel, J., Paul, F. and Sinnecker, T.
Annals of Clinical and Translational Neurology 5 (8): 900-912. August 2018

Novel strategy for the preparation of 3-perfluoroalkylated-2 H-indazole derivatives.
Bel Abed, H., Weißing, N., Schoene, J., Paulus, J., Sewald, N. and Nazaré, M.
Tetrahedron Letters 59 (19): 1813-1815. 9 May 2018

CCR7 on CD4(+) T cells plays a crucial role in the induction of experimental autoimmune encephalomyelitis.
Belikan, P., Bühler, U., Wolf, C., Pramanik, G.K., Gollan, R., Zipp, F. and Siffrin, V.
Journal of Immunology 200 (8): 2554-2562. 15 April 2018

The effectiveness of acupuncture and mindfulness-based stress reduction (MBSR) for patients with multiple sclerosis associated fatigue: a study protocol and its rationale for a randomized controlled trial.
Bellmann-Strobl, J., Pach, D., Chang, Y., Pasura, L., Liu, B., Jäger, S.F., Loerch, R., Jin, L., Blödt, S., Brinkhaus, B., Ortiz, M., Reinhold, T., Roll, S., Binting, S., Paul, F., Witt, C.M. and Shi, X.
European Journal of Integrative Medicine 20 : 6-15. June 2018

CRISPR correction of the PRKAG2 gene mutation in the patient's iPSC-derived cardiomyocytes eliminates the electrophysiological and structural abnormalities.
Ben Jehuda, R., Eisen, B., Shemer, Y., Mekies, L.N., Szantai, A., Reiter, I., Cui, H., Guan, K., Haron-Khun, S., Freimark, D., Sperling, S.R., Gherghiceanu, M., Arad, M. and Binah, O.
Heart Rhythm 15 (2): 267-276. February 2018

The c-Myc/miR17-92/PTEN axis tunes PI3K activity to control expression of recombination activating genes in early B cell development.
Benhamou, D., Labi, V., Getahun, A., Benchetrit, E., Dowery, R., Rajewsky, K., Cambier, J.C. and Melamed, D.
Frontiers in Immunology 9 : 2715. November 2018

Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues.
Benndorf, R., Gilmont, R.R., Hirano, S., Ransom, R.F., Jungblut, P.R., Bommer, M., Goldman, J.E. and Welsh, M.J.
Cell Stress & Chaperones 23 (5): 813-826. September 2018

Deletion of protein kinase D1 in pancreatic β-cells impairs insulin secretion in high-fat diet-fed mice.
Bergeron, V., Ghislain, J., Vivot, K., Tamarina, N., Philipson, L.H., Fielitz, J. and Poitout, V.
Diabetes 67 (1): 71-77. January 2018

PolNet: a tool to quantify network-level cell polarity and blood flow in vascular remodeling.
Bernabeu, M.O., Jones, M.L., Nash, R.W., Pezzarossa, A., Coveney, P.V., Gerhardt, H. and Franco, C.A.
Biophysical Journal 114 (9): 2052-2058. 8 May 2018

Potassium channel-based optogenetic silencing.
Bernal Sierra, Y.A., Rost, B.R., Pofahl, M., Fernandes, A.M., Kopton, R.A., Moser, S., Holtkamp, D., Masala, N., Beed, P., Tukker, J.J., Oldani, S., Bönigk, W., Kohl, P., Baier, H., Schneider-Warme, F., Hegemann, P., Beck, H., Seifert, R. and Schmitz, D.
Nature Communications 9 (1): 4611. 5 November 2018

Understanding chromatin structure: efficient computational implementation of polymer physics models.
Bianco, S., Annunziatella, C., Esposito, A., Fiorillo, L., Conte, M., Campanile, R. and Chiariello, A.M.
Lecture Notes in Computer Science 11339 : 680-691. 2018

Polymer physics predicts the effects of structural variants on chromatin architecture.
Bianco, S., Lupiáñez, D.G., Chiariello, A.M., Annunziatella, C., Kraft, K., Schöpflin, R., Wittler, L., Andrey, G., Vingron, M., Pombo, A., Mundlos, S. and Nicodemi, M.
Nature Genetics 50 (5): 662-667. May 2018

Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid.
Birol, M., Kumar, S., Rhoades, E. and Miranker, A.D.
Nature Communications 9 (1): 1312. 3 April 2018

Omics-based approach reveals complement-mediated inflammation in chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).
Blaabjerg, M., Hemdrup, A.L., Drici, L., Ruprecht, K., Garred, P., Höftberger, R., Kristensen, B.W., Kondziella, D., Sejbaek, T., Hansen, S.W., Nielsen, H.H., Jensen, P., Meyer, M., Paul, F., Lassmann, H., Larsen, M.R. and Illes, Z.
Frontiers in Immunology 9 : 741. 23 April 2018

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J., Kieback, E., Marino, S.F., Oden, F., Westermann, J., Chmielewski, M., Abken, H., Uckert, W., Höpken, U.E. and Rehm, A.
Molecular Therapy 26 (8): 1906-1920. 1 August 2018

Exome-wide analysis of mutational burden in patients with typical and atypical Rolandic epilepsy.
Bobbili, D.R., Lal, D., May, P., Reinthaler, E.M., Jabbari, K., Thiele, H., Nothnagel, M., Jurkowski, W., Feucht, M., Nürnberg, P., Lerche, H., Zimprich, F., Krause, R., Neubauer, B.A., Reinthaler, E.M., Zimprich, F., Feucht, M., Steinböck, H., Neophytou, B., Geldner, J., Gruber-Sedlmayr, U., Haberlandt, E., Ronen, G.M., Altmüller, J., Lal, D., Nürnberg, P., Sander, T., Thiele, H., Krause, R., May, P., Balling, R., Lerche, H. and Neubauer, B.A.
European Journal of Human Genetics 26 (2): 258-264. February 2018

Ketogenic diets attenuate cyclooxygenase and lipoxygenase gene expression in multiple sclerosis.
Bock, M., Karber, M. and Kuhn, H.
EBioMedicine 36 : 293-303. October 2018

Exon junction complexes suppress spurious splice sites to safeguard transcriptome integrity.
Boehm, V., Britto-Borges, T., Steckelberg, A.L., Singh, K.K., Gerbracht, J.V., Gueney, E., Blazquez, L., Altmüller, J., Dieterich, C. and Gehring, N.H.
Molecular Cell 72 (3): 482-495. 1 November 2018

Somatostatin 2 receptor activation in the rostral ventrolateral medulla does not mediate the decompensatory phase of haemorrhage.
Bokiniec, P., Burke, P.G.R., Turner, A.J., McMullan, S. and Goodchild, A.K.
Shock 50 (3): 331-338. September 2018

The neural circuits of thermal perception.
Bokiniec, P., Zampieri, N., Lewin, G.R. and Poulet, J.F.A.
Current Opinion in Neurobiology 52 : 98-106. October 2018

Possible role of CYP450 generated omega-3/omega-6 PUFA metabolites in the modulation of blood pressure and vascular function in obese children.
Bonafini, S., Giontella, A., Tagetti, A., Marcon, D., Montagnana, M., Benati, M., Gaudino, R., Cavarzere, P., Karber, M., Rothe, M., Minuz, P., Antonazzi, F., Maffeis, C., Schunck, W.H. and Fava, C.
Nutrients 10 (11): 1689. 5 November 2018

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.
Bonnin, E., Cabochette, P., Filosa, A., Jühlen, R., Komatsuzaki, S., Hezwani, M., Dickmanns, A., Martinelli, V., Vermeersch, M., Supply, L., Martins, N., Pirenne, L., Ravenscroft, G., Lombard, M., Port, S., Spillner, C., Janssens, S., Roets, E., Van Dorpe, J., Lammens, M., Kehlenbach, R.H., Ficner, R., Laing, N.G., Hoffmann, K., Vanhollebeke, B. and Fahrenkrog, B.
PLoS Genetics 14 (12): e1007845. 13 December 2018

ATP6AP2 over-expression causes morphological alterations in the hippocampus and in hippocampus-related behaviour.
Bracke, A., Schäfer, S., von Bohlen und Halbach, V., Klempin, F., Bente, K., Bracke, K., Staar, D., van den Brandt, J., Harzsch, S., Bader, M., Wenzel, U.O., Peters, J. and von Bohlen und Halbach, O.
Brain Structure & Function 223 (5): 2287-2302. June 2018

Frequent retinal ganglion cell damage after acute optic neuritis.
Brandt, A.U., Specovius, S., Oberwahrenbrock, T., Zimmermann, H.G., Paul, F. and Costello, F.
Multiple Sclerosis and Related Disorders 22 : 141-147. May 2018

Self-perception and determinants of color vision in Parkinson's disease.
Brandt, A.U., Zimmermann, H.G., Oberwahrenbrock, T., Isensee, J., Müller, T. and Paul, F.
Journal of Neural Transmission 125 (2): 145-152. February 2018

Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.
Braun, D.A., Lovric, S., Schapiro, D., Schneider, R., Marquez, J., Asif, M., Hussain, M.S., Daga, A., Widmeier, E., Rao, J., Ashraf, S., Tan, W., Lusk, C.P., Kolb, A., Jobst-Schwan, T., Schmidt, J.M., Hoogstraten, C.A., Eddy, K., Kitzler, T.M., Shril, S., Moawia, A., Schrage, K., Khayyat, A.I.A., Lawson, J.A., Gee, H.Y., Warejko, J.K., Hermle, T., Majmundar, A.J., Hugo, H., Budde, B., Motameny, S., Altmüller, J., Noegel, A. A., Fathy, H.M., Gale, D.P., Waseem, S.S., Khan, A., Kerecuk, L., Hashmi, S., Mohebbi, N., Ettenger, R., Serdaroğlu, E., Alhasan, K.A., Hashem, M., Goncalves, S., Ariceta, G., Ubetagoyena, M., Antonin, W., Baig, S.M., Alkuraya, F.S., Shen, Q., Xu, H., Antignac, C., Lifton, R.P., Mane, S., Nürnberg, P., Khokha, M.K. and Hildebrandt, F.
Journal of Clinical Investigation 128 (10): 4313-4328. 1 October 2018

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation.
Breglio, K.F., Amato, R., Eastman, R., Lim, P., Sa, J.M., Guha, R., Ganesan, S., Dorward, D.W., Klumpp-Thomas, C., McKnight, C., Fairhurst, R.M., Roberts, D., Thomas, C. and Simon, A.K.
Malaria Journal 17 (1): 391. 26 October 2018

Deletion of claudin-10 rescues claudin-16-deficient mice from hypomagnesemia and hypercalciuria.
Breiderhoff, T., Himmerkus, N., Drewell, H., Plain, A., Guenzel, D., Mutig, K., Willnow, T.E., Müller, D. and Bleich, M.
Kidney International 93 (3): 580-588. March 2018

Mechanisms of targeting the MDM2-p53-FOXM1 axis in well-differentiated intestinal neuroendocrine tumors.
Briest, F., Grass, I., Sedding, D., Moebs, M., Christen, F., Benecke, J., Fuchs, K., Mende, S., Kaemmerer, D., Saenger, J., Kunze, A., Geisler, C., Freitag, H., Lewens, F., Worpenberg, L., Iwaszkiewicz, S., Siegmund, B., Walther, W., Hummel, M. and Grabowski, P.
Neuroendocrinology 107 (1): 1-23. July 2018

TPH2 deficiency influences neuroplastic mechanisms and alters the response to an acute stress in a sex specific manner.
Brivio, P., Sbrini, G., Peeva, P., Todiras, M., Bader, M., Alenina, N. and Calabrese, F.
Frontiers in Molecular Neuroscience 11 : 389. 30 October 2018

Species-specific activity of antibacterial drug combinations.
Brochado, A.R., Telzerow, A., Bobonis, J., Banzhaf, M., Mateus, A., Selkrig, J., Huth, E., Bassler, S., Zamarreño Beas, J., Zietek, M., Ng, N., Foerster, S., Ezraty, B., Py, B., Barras, F., Savitski, M.M., Bork, P., Göttig, S. and Typas, A.
Nature 559 (7713): 259-263. July 2018

Mutations in plasmalemma vesicle-associated protein cause severe syndromic protein-losing enteropathy.
Broekaert, I.J., Becker, K., Gottschalk, I., Körber, F., Dötsch, J., Thiele, H., Altmüller, J., Nürnberg, P., Hünseler, C. and Cirak, S.
Journal of Medical Genetics 55 (9): 637-640. September 2018

Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial.
Burock, S., Daum, S., Keilholz, U., Neumann, K., Walther, W. and Stein, U.
BMC Cancer 18 (1): 297. 15 March 2018

The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.
Bégay, V., Baumeier, C., Zimmermann, K., Heuser, A. and Leutz, A.
Scientific Reports 8 (1): 8417. 30 May 2018

Routes to, from and within the subiculum.
Böhm, C., Peng, Y., Geiger, J.R.P. and Schmitz, D.
Cell and Tissue Research 373 (3): 557-563. September 2018

GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis.
Cabral-Marques, O., Marques, A., Giil, L.M., De Vito, R., Rademacher, J., Günther, J., Lange, T., Humrich, J.Y., Klapa, S., Schinke, S., Schimke, L.F., Marschner, G., Pitann, S., Adler, S., Dechend, R., Müller, D.N., Braicu, I., Sehouli, J., Schulze-Forster, K., Trippel, T., Scheibenbogen, C., Staff, A., Mertens, P.R., Löbel, M., Mastroianni, J., Plattfaut, C., Gieseler, F., Dragun, D., Engelhardt, B.E., Fernandez-Cabezudo, M.J., Ochs, H.D., Al-Ramadi, B.K., Lamprecht, P., Mueller, A., Heidecke, H. and Riemekasten, G.
Nature Communications 9 (1): 5224. 6 December 2018

Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis.
Campa, C.C., Silva, R.L., Margaria, J.P., Pirali, T., Mattos, M.S., Kraemer, L.R., Reis, D.C., Grosa, G., Copperi, F., Dalmarco, E.M., Lima-Júnior, R.C.P., Aprile, S., Sala, V., Dal Bello, F., Prado, D.S., Alves-Filho, J.C., Medana, C., Cassali, G.D., Tron, G.C., Teixeira, M.M., Ciraolo, E., Russo, R.C. and Hirsch, E.
Nature Communications 9 (1): 5232. 12 December 2018

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.
Cantù, C., Felker, A., Zimmerli, D., Prummel, K.D., Cabello, E.M., Chiavacci, E., Méndez-Acevedo, K.M., Kirchgeorg, L., Burger, S., Ripoll, J., Valenta, T., Hausmann, G., Vilain, N., Aguet, M., Burger, A., Panáková, D., Basler, K. and Mosimann, C.
Genes & Development 32 (21-22): 1443-1458. 1 November 2018

Cytosolic DNA sensing promotes macrophage transformation and governs myocardial ischemic injury.
Cao, D.J., Schiattarella, G.G., Villalobos, E., Jiang, N., May, H.I., Li, T., Chen, Z.J., Gillette, T.G. and Hill, J.A.
Circulation 137 (24): 2613-2634. 12 June 2018

SPECT/MRI INSERT compatibility: assessment, solutions, and design guidelines.
Carminati, M., Montagnani, G.L., Occhipinti, M., Kuehne, A., Niendorf, T., Nagy, K., Nagy, A., Czeller, M. and Fiorini, C.
IEEE Transactions on Radiation and Plasma Medical Sciences 2 (4): 369-379. July 2018

A global ocean atlas of eukaryotic genes.
Carradec, Q., Pelletier, E., Da Silva, C., Alberti, A., Seeleuthner, Y., Blanc-Mathieu, R., Lima-Mendez, G., Rocha, F., Tirichine, L., Labadie, K., Kirilovsky, A., Bertrand, A., Engelen, S., Madoui, M.A., Méheust, R., Poulain, J., Romac, S., Richter, D.J., Yoshikawa, G., Dimier, C., Kandels-Lewis, S., Picheral, M., Searson, S., Jaillon, O., Aury, J.M., Karsenti, E., Sullivan, M.B., Sunagawa, S., Bork, P., Not, F., Hingamp, P., Raes, J., Guidi, L., Ogata, H., De Vargas, C., Iudicone, D., Bowler, C. and Wincker, P.
Nature Communications 9 (1): 373. 25 January 2018

Sustained MAPK/ERK activation in adult Schwann cells impairs nerve repair.
Cervellini, I., Galino, J., Zhu, N., Allen, S., Birchmeier, C. and Bennett, D.L.
Journal of Neuroscience 38 (3): 679-690. 17 January 2018

Multiscale modeling and numerical simulation of calcium cycling in cardiac myocytes.
Chamakuri, N., Neubert, W., Gilbert, S., Vierheller, J., Warnecke, G. and Falcke, M.
Multiscale Modeling & Simulation 16 (3): 1115-1145. 12 July 2018

Longitudinal study of multiple sclerosis lesions using ultra-high field (7T) multiparametric MR imaging.
Chawla, S., Kister, I., Sinnecker, T., Wuerfel, J., Brisset, J.C., Paul, F. and Ge, Y.
PLoS ONE 13 (9): e0202918. 13 September 2018

Adaptive and reversible resistance to Kras inhibition in pancreatic cancer cells.
Chen, P.Y., Muzumdar, M.D., Dorans, K.J., Robbins, R.A., Bhutkar, A., Del Rosario, A.M., Mertins, P., Qiao, J., Schaefer, C., Gertler, F.B., Carr, S.A. and Jacks, T.
Cancer Research 78 (4): 985-1002. 15 February 2018

Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways.
Chen, W., Kang, K.L., Alshaikh, A., Varma, S., Lin, Y.L., Shin, K.H., Kim, R., Wang, C.Y., Park, N.H., Walentin, K., Schmidt-Ott, K.M. and Kang, M.K.
Oncogenesis 7 (5): 38. 8 May 2018

Human papillomavirus 16 E6 induces FoxM1B in oral keratinocytes through GRHL2.
Chen, W., Shimane, T., Kawano, S., Alshaikh, A., Kim, S.Y, Chung, S.H., Kim, R.H., Shin, K.H., Walentin, K., Park, N.H., Schmidt-Ott, K.M. and Kang, M.K.
Journal of Dental Research 97 (7): 795-802. 1 July 2018

Pervasive, coordinated protein-level changes driven by transcript isoform switching during meiosis.
Cheng, Z., Otto, G.M., Powers, E.N., Keskin, A., Mertins, P., Carr, S.A., Jovanovic, M. and Brar, G.A.
Cell 172 (5): 910-923. 22 February 2018

Measurement of intracellular concentration of fluorescently-labeled targets in living cells.
Cherkas, V., Grebenyuk, S., Osypenko, D., Dovgan, A.V., Grushevskyi, E.O., Yedutenko, M., Sheremet, Y., Dromaretsky, A., Bozhenko, A., Agashkov, K., Kononenko, N.I. and Belan, P.
PLoS ONE 13 (4): e0194031. 25 April 2018

NOTCH activity differentially affects alternative cell fate acquisition and maintenance.
Cheung, L., Le Tissier, P., Goldsmith, S.G., Treier, M., Lovell-Badge, R. and Rizzoti, K.
eLife 7 : e33318. 26 March 2018

The scaling features of the 3D organization of chromosomes are highlighted by a transformation à la Kadanoff of Hi-C data.
Chiariello, A.M., Bianco, S., Annunziatella, C., Esposito, A. and Nicodemi, M.
EPL 120 (4): 40004. 8 February 2018

MRI-based methods for spinal cord atrophy evaluation: a comparison of cervical cord cross-sectional area, cervical cord volume, and full spinal cord volume in patients with aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders.
Chien, C., Brandt, A.U., Schmidt, F., Bellmann-Strobl, J., Ruprecht, K., Paul, F. and Scheel, M.
American Journal of Neuroradiology 39 (7): 1362-1368. 1 July 2018

Cardiac pacemaker channel (HCN4) inhibition and atrial arrhythmogenesis after releasing cardiac sympathetic activation.
Chobanyan-Jürgens, K., Heusser, K., Duncker, D., Veltmann, C., May, M., Mehling, H., Luft, F.C., Schröder, C., Jordan, J. and Tank, J.
Scientific Reports 8 (1): 7748. 17 May 2018

Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
Choi, I.K., Wang, Z., Ke, Q., Hong, M., Qian, Y., Zhao, X., Liu, Y., Kim, H.J., Ritz, J., Cantor, H., Rajewsky, K., Wucherpfennig, K.W. and Zhang, B.
Proceedings of the National Academy of Sciences of the United States of America 115 (4): E686-E695. January 2018

Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon(+) α-cells.
Cigliola, V., Ghila, L., Thorel, F., van Gurp, L., Baronnier, D., Oropeza, D., Gupta, S., Miyatsuka, T., Kaneto, H., Magnuson, M.A., Osipovich, A.B., Sander, M., Wright, C.E.V., Thomas, M.K., Furuyama, K., Chera, S. and Herrera, P.L.
Nature Cell Biology 20 (11): 1267-1277. November 2018

B1a B cells require autophagy for metabolic homeostasis and self-renewal.
Clarke, A.J., Riffelmacher, T., Braas, D., Cornall, R.J. and Simon, A.K.
Journal of Experimental Medicine 215 (2): 399-413. 5 February 2018

Barreloid borders and neuronal activity shape panglial gap junction-coupled networks in the mouse thalamus.
Claus, L., Philippot, C., Griemsmann, S., Timmermann, A., Jabs, R., Henneberger, C., Kettenmann, H. and Steinhaeuser, C.
Cerebral Cortex 28 (1): 213-222. 1 January 2018

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR.
Clauss, J., Obenaus, M., Miskey, C., Ivics, Z., Izsvák, Z., Uckert, W. and Bunse, M.
Human Gene Therapy 29 (5): 569-584. May 2018

Similarity of the dog and human gut microbiomes in gene content and response to diet.
Coelho, L.P., Kultima, J.R., Costea, P.I., Fournier, C., Pan, Y., Czarnecki-Maulden, G., Hayward, M.R., Forslund, S.K., Schmidt, T.S.B., Descombes, P., Jackson, J.R., Li, Q. and Bork, P.
Microbiome 6 (1): 72. 19 April 2018

Multi-level proteomics identifies CT45 as a chemosensitivity mediator and immunotherapy target in ovarian cancer.
Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S.D., López-Méndez, B., Nilsson, J., Mund, A., Mann, M. and Curtis, M.
Cell 175 (1): 159-170. 20 September 2018

Low-frequency and rare-coding variation contributes to multiple sclerosis risk.
Cotsapas, C.
Cell 175 (6): 1679-1687. 29 November 2018

MetExplore: collaborative edition and exploration of metabolic networks.
Cottret, L., Frainay, C., Chazalviel, M., Cabanettes, F., Gloaguen, Y., Camenen, E., Merlet, B., Heux, S., Portais, J.C., Poupin, N., Vinson, F. and Jourdan, F.
Nucleic Acids Research 46 (W1): W495-W502. 2 July 2018

Imaging of endothelial cell dynamic behavior in zebrafish.
Coxam, B. and Gerhardt, H.
Methods in Molecular Biology 1846 : 181-195. 2018

Acquisition and reconstruction of 4D surfaces of axolotl embryos with the flipping stage robotic microscope.
Crawford-Young, S.J., Dittapongpitch, S., Gordon, R. and Harrington, K.I.S.
Biosystems 173 : 214-220. November 2018

Polycystin-2-dependent control of cardiomyocyte autophagy.
Criollo, A., Altamirano, F., Pedrozo, Z., Schiattarella, G.G., Li, D.L., Rivera-Mejías, P., Sotomayor-Flores, C., Parra, V., Villalobos, E., Battiprolu, P.K., Jiang, N., May, H.I., Morselli, E., Somlo, S., de Smedt, H., Gillette, T.G., Lavandero, S. and Hill, J.A.
Journal of Molecular and Cellular Cardiology 118 : 110-121. May 2018

The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages.
Czimmerer, Z., Daniel, B., Horvath, A., Rückerl, D., Nagy, G., Kiss, M., Peloquin, M., Budai, M.M., Cuaranta-Monroy, I., Simandi, Z., Steiner, L., Nagy, B., Poliska, S., Banko, C., Bacso, Z., Schulman, I.G., Sauer, S., Deleuze, J.F., Allen, J.E., Benko, S. and Nagy, L.
Immunity 48 (1): 75-90. 16 January 2018

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.
Czimmerer, Z., Nagy, Z.S., Nagy, G., Horvath, A., Silye-Cseh, T., Kriston, A., Jonas, D., Sauer, S., Steiner, L., Daniel, B., Deleuze, J.F. and Nagy, L.
Molecular and Cellular Endocrinology 471 : 63-74. 15 August 2018

Genome-wide analysis of barrett's adenocarcinoma. a first step towards identifying patients at risk and developing therapeutic paths.
Dai, Y., Wang, Q., Gonzalez Lopez, A., Anders, M., Malfertheiner, P., Vieth, M. and Kemmner, W.
Translational Oncology 11 (1): 116-124. February 2018

The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory.
Daniel, B., Nagy, G., Czimmerer, Z., Horvath, A., Hammers, D.W., Cuaranta-Monroy, I., Poliska, S., Tzerpos, P., Kolostyak, Z., Hays, T.T., Patsalos, A., Houtman, R., Sauer, S., Francois-Deleuze, J., Rastinejad, F., Balint, B.L., Sweeney, H.L. and Nagy, L.
Immunity 49 (4): 615-626. 16 October 2018

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.
Daniel, B., Nagy, G., Horvath, A., Czimmerer, Z., Cuaranta-Monroy, I., Poliska, S., Hays, T.T., Sauer, S., Francois-Deleuze, J. and Nagy, L.
Nucleic Acids Research 46 (9): 4425-4439. 18 May 2018

iPath3.0: interactive pathways explorer v3.
Darzi, Y., Letunic, I., Bork, P. and Yamada, T.
Nucleic Acids Research 46 (W1): W510-W513. 2 July 2018

ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis.
Das, K.K., Heeg, S., Pitarresi, J.R., Reichert, M., Bakir, B., Takano, S., Kopp, J.L., Wahl-Feuerstein, A., Hicks, P., Sander, M. and Rustgi, A.K.
Developmental Dynamics 247 (6): 854-866. June 2018

Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4.
Dauksaite, V. and Gotthardt, M.
Nucleic Acids Research 46 (10): 5227-5238. 1 June 2018

Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability.
Dawes, J.M., Weir, G.A., Middleton, S.J., Patel, R., Chisholm, K.I., Pettingill, P., Peck, L.J., Sheridan, J., Shakir, A., Jacobson, L., Gutierrez-Mecinas, M., Galino, J., Walcher, J., Kühnemund, J., Kuehn, H., Sanna, M.D., Lang, B., Clark, A.J., Themistocleous, A.C., Iwagaki, N., West, S.J., Werynska, K., Carroll, L., Trendafilova, T., Menassa, D.A., Giannoccaro, M.P., Coutinho, E., Cervellini, I., Tewari, D., Buckley, C., Leite, M.I., Wildner, H., Zeilhofer, H.U., Peles, E., Todd, A.J., McMahon, S.B., Dickenson, A.H., Lewin, G.R., Vincent, A. and Bennett, D.L.
Neuron 97 (4): 806-822. 21 February 2018

EGFR activation triggers cellular hypertrophy and lysosomal disease in NAGLU-depleted cardiomyoblasts, mimicking the hallmarks of mucopolysaccharidosis IIIB.
De Pasquale, V., Pezone, A., Sarogni, P., Tramontano, A., Schiattarella, G.G., Avvedimento, V.E., Paladino, S. and Pavone, L.M.
Cell Death & Disease 9 (2): 40. 18 January 2018

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Decaesteker, B., Denecker, G., Van Neste, C., Dolman, E.M., Van Loocke, W., Gartlgruber, M., Nunes, C., De Vloed, F., Depuydt, P., Verboom, K., Rombaut, D., Loontiens, S., De Wyn, J., Kholosy, W.M., Koopmans, B., Essing, A.H.W., Herrmann, C., Dreidax, D., Durinck, K., Deforce, D., van Nieuwerburgh, F., Henssen, A., Versteeg, R., Boeva, V., Schleiermacher, G., van Nes, J., Mestdagh, P., Vanhauwaert, S., Schulte, J.H., Westermann, F., Molenaar, J.J., De Preter, K. and Speleman, F.
Nature Communications 9 (1): 4866. 19 November 2018

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V., Rosen, D.B., Wang, Q., Gazumyan, A., Pai, J.A., Oliveira, T.Y., Sundaravinayagam, D., Zhang, W., Andreani, M., Keller, L., Kieffer-Kwon, K.R., Pękowska, A., Jung, S., Driesner, M., Subbotin, R.I., Casellas, R., Chait, B.T., Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72 (4): 636-649. 15 November 2018

Stage-specific metabolic features of differentiating neurons: implications for toxicant sensitivity.
Delp, J., Gutbier, S., Cerff, M., Zasada, C., Niedenführ, S., Zhao, L., Smirnova, L., Hartung, T., Borlinghaus, H., Schreiber, F., Bergemann, J., Gätgens, J., Beyss, M., Azzouzi, S., Waldmann, T., Kempa, S., Nöh, K. and Leist, M.
Toxicology and Applied Pharmacology 354 : 64-80. 1 September 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais, F., Margaritte-Jeannin, P., Barnes, K.C., Cookson, W.O.C., Altmüller, J., Ang, W., Barr, R.G., Beaty, T.H., Becker, A.B., Beilby, J., Bisgaard, H., Bjornsdottir, U.S., Bleecker, E., Bonnelykke, K., Boomsma, D.I., Bouzigon, E., Brightling, C.E., Brossard, M., Brusselle, G.G., Burchard, E., Burkart, K.M., Bush, A., Chan-Yeung, M., Chung, K.F., Couto Alves, A., Curtin, J.A., Custovic, A., Daley, D., de Jongste, J.C., Del-Rio-Navarro, B.E., Donohue, K.M., Duijts, L., Eng, C., Eriksson, J.G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M.A., Freidin, M.B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S.A, Gilliland, F., Granell, R., Graves, P.E., Gudbjartsson, D.F., Haahtela, T., Heckbert, S.R., Heederik, D., Heinrich, J., Helioevaara, M., Henderson, J., Himes, B.E., Hirose, H., Hirschhorn, J.N., Hofman, A., Holt, P., Hottenga, J., Hudson, T.J., Hui, J., Imboden, M., Ivanov, V., Jaddoe, V.W.V., James, A., Janson, C., Jarvelin, M.R., Jarvis, D., Jones, G., Jonsdottir, I., Jousilahti, P., Kabesch, M., Kähönen, M., Kantor, D.B., Karunas, A.S., Khusnutdinova, E., Koppelman, G.H., Kozyrskyj, A.L., Kreiner, E., Kubo, M., Kumar, R., Kumar, A., Kuokkanen, M., Lahousse, L., Laitinen, T., Laprise, C., Lathrop, M., Lau, S., Lee, Y.A., Lehtimaeki, T., Letort, S., Levin, A.M., Li, G., Liang, L., Loehr, L.R., London, S.J., Loth, D.W., Manichaikul, A., Marenholz, I., Martinez, F.J., Matheson, M.C., Mathias, R.A., Matsumoto, K., Mbarek, H., McArdle, W.L., Melbye, M., Melen, E., Meyers, D., Michel, S., Mohamdi, H., Musk, A.W., Myers, R.A., Nieuwenhuis, M.A.E., Noguchi, E., O'Connor, G.T., Ogorodova, L.M., Palmer, C.D., Palotie, A., Park, J.E., Pennell, C.E., Pershagen, G., Polonikov, A., Postma, D.S., Probst-Hensch, N., Puzyrev, V.P., Raby, B.A., Raitakari, O.T., Ramasamy, A., Rich, S.S., Robertson, C.F., Romieu, I., Salam, M.T., Salomaa, V., Schluenssen, V., Scott, R., Selivanova, P.A., Sigsgaard, T., Simpson, A., Siroux, V., Smith, L.J., Solodilova, M., Standl, M., Stefansson, K., Strachan, D.P., Stricker, B.H., Takahashi, A., Thompson, P.J., Thorleifsson, G., Thorsteinsdottir, U., Tiesler, C.M.T., Torgerson, D.G., Tsunoda, T., Uitterlinden, A.G., van der Valk, R.J.P., Vaysse, A., Vedantam, S., von Berg, A., von Mutius, E., Vonk, J.M., Waage, J., Wareham, N.J., Weiss, S.T., White, W.B., Wickman, M., Widén, E., Willemsen, G., Williams, L.K., Wouters, I.M., Yang, J.J., Zhao, J.H., Moffatt, M.F., Ober, C. and Nicolae, D.L.
Nature Genetics 50 (1): 42-53. January 2018

Nuclear organization in the spinal cord depends on motor neuron lamination orchestrated by catenin and afadin function.
Dewitz, C., Pimpinella, S., Hackel, P., Akalin, A., Jessell, T.M. and Zampieri, N.
Cell Reports 22 (7): 1681-1694. 13 February 2018

Spatiotemporal m(i)RNA architecture and 3' UTR regulation in the C. elegans germline.
Diag, A., Schilling, M., Klironomos, F., Ayoub, S. and Rajewsky, N.
Developmental Cell 47 (6): 785-800. 17 December 2018

Muscle MRI in patients with dysferlinopathy: pattern recognition and implications for clinical trials.
Diaz-Manera, J., Fernandez-Torron, R., LLauger, J., James, M.K., Mayhew, A., Smith, F.E., Moore, U.R., Blamire, A.M., Carlier, P.G., Rufibach, L., Mittal, P., Eagle, M., Jacobs, M., Hodgson, T., Wallace, D., Ward, L., Smith, M., Stramare, R., Rampado, A., Sato, N., Tamaru, T., Harwick, B., Rico Gala, S., Turk, S., Coppenrath, E.M., Foster, G., Bendahan, D., Le Fur, Y., Fricke, S.T., Otero, H., Foster, S.L., Peduto, A., Sawyer, A.M., Hilsden, H., Lochmuller, H., Grieben, U., Spuler, S., Tesi Rocha, C., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Harms, M., Pestronk, A., Krause, S., Schreiber-Katz, O., Walter, M.C., Paradas, C., Hogrel, J.Y., Stojkovic, T., Takeda, S., Mori-Yoshimura, M., Bravver, E., Sparks, S., Bello, L., Semplicini, C., Pegoraro, E., Mendell, J.R., Bushby, K. and Straub, V.
Journal of Neurology Neurosurgery and Psychiatry 89 (10): 1071-1081. October 2018

Apical and basal matrix remodeling control epithelial morphogenesis.
Diaz-de-la-Loza, M.D.C., Ray, R.P., Ganguly, P.S., Alt, S., Davis, J.R., Hoppe, A., Tapon, N., Salbreux, G. and Thompson, B.J.
Developmental Cell 46 (1): 23-39. 2 July 2018

Structural changes of TasA in biofilm formation of Bacillus subtilis.
Diehl, A., Roske, Y., Ball, L., Chowdhury, A., Hiller, M., Molière, N., Kramer, R., Stöppler, D., Worth, C.L., Schlegel, B., Leidert, M., Cremer, N., Erdmann, N., Lopez, D., Stephanowitz, H., Krause, E., van Rossum, B.J., Schmieder, P., Heinemann, U., Turgay, K., Akbey, Ü. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 115 (13): 3237-3242. 27 March 2018

On the relation between filament density, force generation and protrusion rate in mesenchymal cell motility.
Dolati, S., Kage, F., Mueller, J., Müsken, M., Kirchner, M., Dittmar, G., Sixt, M., Rottner, K. and Falcke, M.
Molecular Biology of the Cell 29 (22): 2674-2686. 1 November 2018

Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient.
Doll, S., Kriegmair, M.C., Santos, A., Wierer, M., Coscia, F., Neil, H.M., Porubsky, S., Geyer, P.E., Mund, A., Nuhn, P. and Mann, M.
Molecular Oncology 12 (8): 1296-1307. August 2018

Neuronal adenosine A(2A) receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease.
Domenici, M.R., Chiodi, V., Averna, M., Armida, M., Pèzzola, A., Pepponi, R., Ferrante, A., Bader, M., Fuxe, K. and Popoli, P.
Purinergic Signalling 14 (3): 235-243. September 2018

Hippocampal ripple oscillations and inhibition-first network models: frequency dynamics and response to GABA modulators.
Donoso, J.R., Schmitz, D., Maier, N. and Kempter, R.
Journal of Neuroscience 38 (12): 3124-3146. 21 March 2018

omniCLIP: probabilistic identification of protein-RNA interactions from CLIP-seq data.
Drewe-Boss, P., Wessels, H.H. and Ohler, U.
Genome Biology 19 : 183. 1 November 2018

Arrhythmogenic remodeling of the left ventricle in a porcine model of repaired tetralogy of fallot.
Dubes, V., Benoist, D., Roubertie, F., Gilbert, S.H., Constantin, M., Charron, S., Elbes, D., Vieillot, D., Quesson, B., Cochet, H., Haïssaguerre, M., Rooryck, C., Bordachar, P., Thambo, J.B. and Bernus, O.
Circulation Arrhythmia and Electrophysiology 11 (10): e006059. October 2018

S-palmitoylation is required for the control of growth cone morphology of DRG neurons by CNP-induced cGMP signaling.
Dumoulin, A., Dagane, A., Dittmar, G. and Rathjen, F.G.
Frontiers in Molecular Neuroscience 11 : 345. 24 September 2018

In vivo imaging of MMP-13 activity using a specific polymer-FRET peptide conjugate detects early osteoarthritis and inhibitor efficacy.
Duro-Castano, A., Lim, N.H., Tranchant, I., Amoura, M., Beau, F., Wieland, H., Kingler, O., Herrmann, M., Nazaré, M., Plettenburg, O., Dive, V., Vicent, M.J. and Nagase, H.
Advanced Functional Materials 28 (37): 1802738. 12 September 2018

Brain iron accumulation in Wilson's disease: a longitudinal imaging case study during anticopper treatment using 7.0T MRI and transcranial sonography.
Dusek, P., Skoloudik, D., Maskova, J., Huelnhagen, T., Bruha, R., Zahorakova, D., Niendorf, T., Ruzicka, E., Schneider, S.A. and Wuerfel, J.
Journal of Magnetic Resonance Imaging 47 (1): 282-285. January 2018

Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care.
Döhner, H., Dolnik, A., Tang, L., Seymour, J.F., Minden, M.D., Stone, R.M., Del Castillo, T.B., Al-Ali, H.K., Santini, V., Vyas, P., Beach, C L., MacBeth, K.J., Skikne, B.S., Songer, S., Tu, N., Bullinger, L. and Dombret, H.
Leukemia 32 (12): 2546-2557. December 2018

Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.
Döhner, K., Ramos-Nascimento, A., Bialy, D., Anderson, F., Hickford-Martinez, A., Rother, F., Koithan, T., Rudolph, K., Buch, A., Prank, U., Binz, A., Hügel, S., Lebbink, R.J., Hoeben, R.C., Hartmann, E., Bader, M., Bauerfeind, R. and Sodeik, B.
PLoS Pathogens 14 (1): e1006823. 5 January 2018

Disease modification in multiple sclerosis by flupirtine - results of a randomized placebo controlled phase II trial.
Dörr, J., Wernecke, K.D., Würfel, J., Bellmann-Strobl, J., Siffrin, V., Sättler, M.B., Simons, M., Linsa, A., Tumani, H. and Paul, F.
Frontiers in Neurology 9 : 842. October 2018

Spatial transcriptomics of C. elegans males and hermaphrodites identifies sex-specific differences in gene expression patterns.
Ebbing, A., Vértesy, Á., Betist, M.C., Spanjaard, B., Junker, J.P., Berezikov, E., van Oudenaarden, A. and Korswagen, H.C.
Developmental Cell 47 (6): 801-813. 17 December 2018

Silent witness: dual-species transcriptomics reveals epithelial immunological quiescence to helminth larval encounter and fostered larval development.
Ebner, F., Kuhring, M., Radonic, A., Midha, A., Renard, B.Y. and Hartmann, S.
Frontiers in Immunology 9 : 1868. 15 August 2018

Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit.
Edemann-Callesen, H., Habelt, B., Wieske, F., Jackson, M., Khadka, N., Mattei, D., Bernhardt, N., Heinz, A., Liebetanz, D., Bikson, M., Padberg, F., Hadar, R., Nitsche, N. and Winter, C.
Translational Psychiatry 8 (1): 11. 10 January 2018

Crosstalk between core-multishell nanocarriers for cutaneous drug delivery and antigen-presenting cells of the skin.
Edlich, A., Volz, P., Brodwolf, R., Unbehauen, M., Mundhenk, L., Gruber, A.D., Hedtrich, S., Haag, R., Alexiev, U. and Kleuser, B.
Biomaterials 162 : 60-70. April 2018

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.
Eggert, S., Gonzalez, A.C., Thomas, C., Schilling, S., Schwarz, S.M., Tischer, C., Adam, V., Strecker, P., Schmidt, V., Willnow, T.E., Hermey, G., Pietrzik, C.U., Koo, E.H. and Kins, Stefan
Cellular and Molecular Life Sciences 75 (2): 301-322. January 2018

Antiproliferative activity of the combination of doxorubicin/quercetin on MCF7 breast cancer cell line: a combined study using colorimetric assay and synchrotron infrared microspectroscopy.
Elmadany, N., Khalil, E., Vaccari, L., Birarda, G., Yousef, I. and Abu-Dahab, R.
Infrared Physics & Technology 95 : 141-147. December 2018

Viral communities among sympatric vampire bats and cattle.
Escalera-Zamudio, M., Taboada, B., Rojas-Anaya, E., Löber, U., Loza-Rubio, E., Arias, C.F. and Greenwood, A.D.
EcoHealth 15 (1): 132-142. March 2018

Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.
Escot, S., Willnow, D., Naumann, H., Di Francescantonio, S. and Spagnoli, F.M.
Nature Communications 9 (1): 5082. 30 November 2018

The stretch to stray on time: resonant length of random walks in a transient.
Falcke, M. and Friedhoff, V.N.
Chaos 28 (5): 053117. 23 May 2018

On the phase space structure of IP(3) induced Ca(2+) signalling and concepts for predictive modeling.
Falcke, M., Moein, M., Tilūnaitė, A., Thul, R. and Skupin, A.
Chaos 28 (4): 045115. 1 April 2018

Differential targeting and signalling of voltage-gated T-type Ca(V) 3.2 and L-type Ca(V) 1.2 channels to ryanodine receptors in mesenteric arteries.
Fan, G., Kaßmann, M., Hashad, A.M., Welsh, D.G. and Gollasch, M.
Journal of Physiology 596 (20): 4863-4877. 15 October 2018

A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit via FRET in a binary system.
Fang, G.M., Chamiolo, J., Kankowski, S., Hövelmann, F., Friedrich, D., Löwer, A., Meier, J.C. and Seitz, O.
Chemical Science 9 (21): 4794-4800. 7 June 2018

Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity.
Farsi, Z., Gowrisankaran, S., Krunic, M., Rammner, B., Woehler, A., Lafer, E.M., Mim, C., Jahn, R. and Milosevic, I.
eLife 7 : e32569. 13 April 2018

Dominant SCN2A mutation causes familial episodic ataxia and impairment of speech development.
Fazeli, W., Becker, K., Herkenrath, P., Düchting, C., Körber, F., Landgraf, P., Nürnberg, P., Altmüller, J., Thiele, H., Koy, A., Liebau, M.C., Simon, T., Dötsch, J. and Cirak, S.
Neuropediatrics 49 (6): 379-384. December 2018

Association of obesity, diabetes and hypertension with cognitive impairment in older age.
Feinkohl, I., Lachmann, G., Brockhaus, W.R., Borchers, F., Piper, S.K., Ottens, T., Nathoe, H., Sauer, A.M., Dieleman, J., Radtke, F., van Dijk, D., Pischon, T. and Spies, C.
Clinical Epidemiology 10 : 853-862. 25 July 2018

Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients.
Feldheim, J., Kessler, A.F., Schmitt, D., Wilczek, L., Linsenmann, T., Dahlmann, M., Monoranu, C.M., Ernestus, R.I., Hagemann, C. and Löhr, M.
OncoTargets and Therapy 11 : 8673-8684. 4 December 2018

Continuous addition of progenitors forms the cardiac ventricle in zebrafish.
Felker, A., Prummel, K.D., Merks, A.M., Mickoleit, M., Brombacher, E.C., Huisken, J., Panáková, D. and Mosimann, C.
Nature Communications 9 (1): 2001. 21 May 2018

A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism.
Fernandes-Rosa, F.L., Daniil, G., Orozco, I.J., Göppner, C., El Zein, R., Jain, V., Boulkroun, S., Jeunemaitre, X., Amar, L., Lefebvre, H., Schwarzmayr, T., Strom, T.M., Jentsch, T.J. and Zennaro, M.C.
Nature Genetics 50 (3): 355-361. March 2018

Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.
Fernández, Á.F., Sebti, S., Wei, Y., Zou, Z., Shi, M., McMillan, K.L., He, C., Ting, T., Liu, Y., Chiang, W.C., Marciano, D.K., Schiattarella, G.G., Bhagat, G., Moe, O.W., Hu, M.C. and Levine, B.
Nature 558 (7708): 136-140. 7 June 2018

Role of perivascular adipose tissue in health and disease.
Fernández-Alfonso, M.S., Somoza, B., Tsvetkov, D., Kuczmanski, A., Dashwood, M. and Gil-Ortega, M.
Comprehensive Physiology 8 (1): 23-59. January 2018

Dendrite-specific amplification of weak synaptic input during network activity in vivo.
Ferrarese, L., Jouhanneau, J.S., Remme, M.W.H., Kremkow, J., Katona, G., Rózsa, B., Schreiber, S. and Poulet, J.F.A.
Cell Reports 24 (13): 3455-3465. 25 September 2018

A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors.
Fink, S., Zugelder, L., Roth, B., Brandt, E., Meloche, S., Izsvák, Z., Bargou, R.C. and Stühmer, T.
PLoS ONE 13 (10): e0205585. 19 October 2018

Association of visual impairment in neuromyelitis optica spectrum disorder with visual network reorganization.
Finke, C., Zimmermann, H., Pache, F., Oertel, F.C., Chavarro, V.S., Kramarenko, Y., Bellmann-Strobl, J., Ruprecht, K., Brandt, A.U. and Paul, F.
JAMA Neurology 75 (3): 296-303. March 2018

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level.
Fischer, J., Kleinau, G., Rutz, C., Zwanziger, D., Khajavi, N., Müller, A., Rehders, M., Brix, K., Worth, C.L., Führer, D., Krude, H., Wiesner, B., Schülein, R. and Biebermann, H.
Cellular and Molecular Life Sciences 75 (12): 2227-2239. June 2018

Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts.
Floegel, A., Kühn, T., Sookthai, D., Johnson, T., Prehn, C., Rolle-Kampczyk, U., Otto, W., Weikert, C., Illig, T., von Bergen, M., Adamski, J., Boeing, H., Kaaks, R. and Pischon, T.
European Journal of Epidemiology 33 (1): 55-66. January 2018

Gearing up to handle the mosaic nature of life in the quest for orthologs.
Forslund, K., Pereira, C., Capella-Gutierrez, S., Sousa da Silva, A., Altenhoff, A., Huerta-Cepas, J., Muffato, M., Patricio, M., Vandepoele, K., Ebersberger, I., Blake, J., Fernández Breis, J.T., Boeckmann, B., Gabaldón, T., Sonnhammer, E., Dessimoz, C. and Lewis, S.
Bioinformatics 34 (2): 323-329. 15 January 2018

Keratinocyte-specific ablation of protease-activated receptor-2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease.
Francis, N., Ayodele, B.A., O'Brien-Simpson, N.M., Birchmeier, W., Pike, R.N., Pagel, C.N. and Mackie, E.J.
Cellular Microbiology 20 (11): e12891. November 2018

Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
Franko, A., Rodriguez Camargo, D.C., Böddrich, A., Garg, D., Rodriguez Camargo, A., Rathkolb, B., Janik, D., Aichler, M., Feuchtinger, A., Neff, F., Fuchs, H., Wanker, E.E., Reif, B., Häring, H.U., Peter, A. and Hrabě de Angelis, M.
Scientific Reports 8 (1): 1116. 18 January 2018

MYB induces the expression of the oncogenic corepressor SKI in acute myeloid leukemia.
Frech, M., Teichler, S., Feld, C., Bouchard, C., Berberich, H., Sorg, K., Mernberger, M., Bullinger, L., Bauer, U.M. and Neubauer, A.
Oncotarget 9 (32): 22423-22435. 27 April 2018

FENS Forum 2018 - Neuer Teilnehmer-Rekord.
Friauf, E. and Kettenmann, H.
Neuroforum 24 (4): 297-299. 9 November 2018

Human axial progenitors generate trunk neural crest cells in vitro.
Frith, T.J.R., Granata, I., Wind, M., Stout, E., Thompson, O., Neumann, K., Stavish, D., Heath, P.R., Ortmann, D., Hackland, J.O.S., Anastassiadis, K., Gouti, M., Briscoe, J., Wilson, V., Johnson, S.L., Placzek, M., Guarracino, M.R., Andrews, P.W. and Tsakiridis, A.
eLife 7 : e35786. 10 August 2018

Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Fritsche-Guenther, R., Zasada, C., Mastrobuoni, G., Royla, N., Rainer, R., Roßner, F., Pietzke, M., Klipp, E., Sers, C. and Kempa, S.
Scientific Reports 8 (1): 9204. 15 June 2018

IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies.
Fung, H.Y.J., Birol, M. and Rhoades, E.
Current Opinion in Structural Biology 49 : 36-43. April 2018

Quantification of the left atrium applying cardiovascular magnetic resonance in clinical routine.
Funk, S., Kermer, J., Doganguezel, S., Schwenke, C., von Knobelsdorff-Brenkenhoff, F. and Schulz-Menger, J.
Scandinavian Cardiovascular Journal 52 (2): 85-92. April 2018

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells.
Gabryšová, L., Alvarez-Martinez, M., Luisier, R., Cox, L.S., Sodenkamp, J., Hosking, C., Pérez-Mazliah, D., Whicher, C., Kannan, Y., Potempa, K., Wu, X., Bhaw, L., Wende, H., Sieweke, M.H., Elgar, G., Wilson, M., Briscoe, J., Metzis, V., Langhorne, J., Luscombe, N.M. and O'Garra, A.
Nature Immunology 19 (5): 497-507. May 2018

Safety and preliminary efficacy of deep transcranial magnetic stimulation in MS-related fatigue.
Gaede, G., Tiede, M., Lorenz, I., Brandt, A.U., Pfueller, C., Dörr, J., Bellmann-Strobl, J., Piper, S.K., Roth, Y., Zangen, A., Schippling, S. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 5 (1): e423. 1 January 2018

Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogels.
Gaetani, R., Aude, S., DeMaddalena, L.L., Strassle, H., Dzieciatkowska, M., Wortham, M., Bender, R.H.F., Nguyen-Ngoc, K.V., Schmid-Schöenbein, G.W., George, S.C., Hughes, C.C.W., Sander, M., Hansen, K.C. and Christman, K.L.
Tissue Engineering Part C Methods 24 (12): 697-708. December 2018

DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia.
Gaidzik, V.I., Weber, D., Paschka, P., Kaumanns, A., Krieger, S., Corbacioglu, A., Krönke, J., Kapp-Schwoerer, S., Krämer, D., Horst, H.A., Schmidt-Wolf, I., Held, G., Kündgen, A., Ringhoffer, M., Götze, K., Kindler, T., Fiedler, W., Wattad, M., Schlenk, R.F., Bullinger, L., Teleanu, V., Schlegelberger, B., Thol, F., Heuser, M., Ganser, A., Döhner, H. and Döhner, K.
Leukemia 32 (1): 30-37. January 2018

MVP: a microbe-phage interaction database.
Gao, N.L., Zhang, C., Zhang, Z., Hu, S., Lercher, M.J., Zhao, X.M., Bork, P., Liu, Z. and Chen, W.H.
Nucleic Acids Research 46 (D1): D700-D707. 4 January 2018

A novel form of RNA double helix based on G·U and C·A(+) wobble base pairing.
Garg, A. and Heinemann, U.
RNA 24 (2): 209-218. February 2018

Downregulation of p53 drives autophagy during human trophoblast differentiation.
Gauster, M., Maninger, S., Siwetz, M., Deutsch, A., El-Heliebi, A., Kolb-Lenz, D., Hiden, U., Desoye, G., Herse, F. and Prokesch, A.
Cellular and Molecular Life Sciences 75 (10): 1839-1855. May 2018

Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.
Gavvovidis, I., Leisegang, M., Willimsky, G., Miller, N.J., Nghiem, P. and Blankenstein, T.
Clinical Cancer Research 24 (15): 3644-3655. August 2018

Active contour method for ILM segmentation in ONH volume scans in retinal OCT.
Gawlik, K., Hausser, F., Paul, F., Brandt, A.U. and Kadas, E.M.
Biomedical Optics Express 9 (12): 6497. 1 December 2018

Integrated proteogenomic approach for identifying degradation motifs in eukaryotic cells.
Geffen, Y., Appleboim, A., Gardner, R.G. and Ravid, T.
Methods in Molecular Biology 1844 : 121-136. 2018

Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation.
Geissler, S., Textor, M., Stumpp, S., Seitz, S., Lekaj, A., Brunk, S., Klaassen, S., Schinke, T., Klein, C., Mundlos, S., Kornak, U. and Kühnisch, J.
PLoS ONE 13 (6): e0198510. 7 June 2018

First genome-wide CNV mapping in FELIS CATUS using next generation sequencing data.
Genova, F., Longeri, M., Lyons, L.A., Bagnato, A. and Strillacci, M.G.
BMC Genomics 19 (1): 895. 10 December 2018

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.
George, J., Walter, V., Peifer, M., Alexandrov, L.B., Seidel, D., Leenders, F., Maas, L., Müller, C., Dahmen, I., Delhomme, T.M., Ardin, M., Leblay, N., Byrnes, G., Sun, R., De Reynies, A., McLeer-Florin, A., Bosco, G., Malchers, F., Menon, R., Altmüller, J., Becker, C., Nürnberg, P., Achter, V., Lang, U., Schneider, P.M., Bogus, M., Soloway, M.G., Wilkerson, M.D., Cun, Y., McKay, J.D., Moro-Sibilot, D., Brambilla, C.G., Lantuejoul, S., Lemaitre, N., Soltermann, A., Weder, W., Tischler, V., Brustugun, O.T., Lund-Iversen, M., Helland, Å., Solberg, S., Ansén, S., Wright, G., Solomon, B., Roz, L., Pastorino, U., Petersen, I., Clement, J.H., Sänger, J., Wolf, J., Vingron, M., Zander, T., Perner, S., Travis, W.D., Haas, S.A., Olivier, M., Foll, M., Büttner, R., Hayes, D.N., Brambilla, E., Fernandez-Cuesta, L. and Thomas, R.K.
Nature Communications 9 (1): 1048. 13 March 2018

Strand-seq enables reliable separation of long reads by chromosome via expectation maximization.
Ghareghani, M., Porubskỳ, D., Sanders, A.D., Meiers, S., Eichler, E.E., Korbel, J.O. and Marschall, T.
Bioinformatics 34 (13): i115-i123. 1 July 2018

Biallelic mutations in ADPRHL2, encoding ADP-ribosylhydrolase 3, lead to a degenerative pediatric stress-induced epileptic ataxia syndrome.
Ghosh, S.G., Becker, K., Huang, H., Dixon-Salazar, T., Chai, G., Salpietro, V., Al-Gazali, L., Waisfisz, Q., Wang, H., Vaux, K.K., Stanley, V., Manole, A., Akpulat, U., Weiss, M.M., Efthymiou, S., Hanna, M.G., Minetti, C., Striano, P., Pisciotta, L., De Grandis, E., Altmüller, J., Weixler, L., Nürnberg, P., Thiele, H., Yis, U., Okur, T.D., Polat, A.I., Amiri, N., Doosti, M., Karimani, E.G., Toosi, M.B., Haddad, G., Karakaya, M., Wirth, B., van Hagen, J.M., Wolf, N.I., Maroofian, R., Houlden, H., Cirak, S. and Gleeson, J.G.
American Journal of Human Genetics 103 (3): 431-439. 6 September 2018

Spatial modeling of the membrane-cytosolic interface in protein kinase signal transduction.
Giese, W., Milicic, G., Schröder, A. and Klipp, E.
PLoS Computational Biology 14 (4): e1006075. 9 April 2018

Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels.
Giulbudagian, M., Hönzke, S., Bergueiro, J., Işık, D., Schumacher, F., Saeidpour, S., Lohan, S.B., Meinke, M.C., Teutloff, C., Schäfer-Korting, M., Yealland, G., Kleuser, B., Hedtrich, S. and Calderón, M.
Nanoscale 10 (1): 469-479. 7 January 2018

Breaking the barrier - potent anti-inflammatory activity following efficient topical delivery of etanercept using thermoresponsive nanogels.
Giulbudagian, M., Yealland, G., Hönzke, S., Edlich, A., Geisendörfer, B., Kleuser, B., Hedtrich, S. and Calderón, M.
Theranostics 8 (2): 450-463. 1 January 2018

NKp46 receptor-mediated interferon-γ production by natural killer cells increases fibronectin 1 to alter tumor architecture and control metastasis.
Glasner, A., Levi, A., Enk, J., Isaacson, B., Viukov, S., Orlanski, S., Scope, A., Neuman, T., Enk, C.D., Hanna, J.H., Sexl, V., Jonjic, S., Seliger, B., Zitvogel, L. and Mandelboim, O.
Immunity 48 (1): 107-119. 16 January 2018

Continuous blood glucose monitoring reveals enormous circadian variations in pregnant diabetic rats.
Golic, M., Kräker, K., Fischer, C., Alenina, N., Haase, N., Herse, F., Schütte, T., Henrich, W., Müller, D.N., Busjahn, A., Bader, M. and Dechend, R.
Frontiers in Endocrinology 9 : 271. 29 May 2018

Diabetes mellitus in pregnancy leads to growth restriction and epigenetic modification of the Srebf2 gene in rat fetuses.
Golic, M., Stojanovska, V., Bendix, I., Wehner, A., Herse, F., Haase, N., Kräker, K., Fischer, C., Alenina, N., Bader, M., Schütte, T., Schuchardt, M., van der Giet, M., Henrich, W., Muller, D.N., Felderhoff-Müser, U., Scherjon, S., Plösch, T. and Dechend, R.
Hypertension 71 (5): 911-920. May 2018

The case: chronic kidney disease unmasked by single-subject research.
Gollasch, B., Wischnewski, O., Rudolph, B., Anistan, Y.M., Luft, F.C. and Gollasch, M.
Case Reports in Nephrology and Dialysis 8 (2): 90-97. 16 May 2018

Dieter Klaus und die Bluthochdruckforschung.
Gollasch, M., Tsvetkov, D. and Müller, D.
Nieren- und Hochdruckkrankheiten 47 (1): 40-46. January 2018

Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Gonçalves, I.C.G., Brecht, J., Thelen, M.P., Rehorst, W.A., Peters, M., Lee, H.J., Motameny, S., Torres-Benito, L., Ebrahimi-Fakhari, D., Kononenko, N.L., Altmüller, J., Vilchez, D., Sahin, M., Wirth, B. and Kye, M.J.
Scientific Reports 8 (1): 7907. 21 May 2018

UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Gozdecka, M., Meduri, E., Mazan, M., Tzelepis, K., Dudek, M., Knights, A.J., Pardo, M., Yu, L., Choudhary, J.S., Metzakopian, E., Iyer, V., Yun, H., Park, N., Varela, I., Bautista, R., Collord, G., Dovey, O., Garyfallos, D.A., De Braekeleer, E., Kondo, S., Cooper, J., Göttgens, B., Bullinger, L., Northcott, P.A., Adams, D., Vassiliou, G.S. and Huntly, B.J.P.
Nature Genetics 50 (6): 883-894. June 2018

Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.
Graf, L., Dick, A., Sendker, F., Barth, E., Marz, M., Daumke, O. and Kochs, G.
Journal of Biological Chemistry 293 (9): 3056-3072. 2 March 2018

Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury.
Gross, A., Pack, L.A.P., Schacht, G.M., Kant, S., Ungewiss, H., Meir, M., Schlegel, N., Preisinger, C., Boor, P., Guldiken, N., Krusche, C.A., Sellge, G., Trautwein, C., Waschke, J., Heuser, A., Leube, R.E. and Strnad, P.
Mucosal Immunology 11 (6): 1630-1639. 1 November 2018

Transcriptional and translational differences of microglia from male and female brains.
Guneykaya, D., Ivanov, A., Perez Hernandez, D., Haage, V., Wojtas, B., Meyer, N., Maricos, M., Jordan, P., Buonfiglioli, A., Gielniewski, B., Ochocka, N., Cömert, C., Friedrich, C., Suarez Artiles, L., Kaminska, B., Mertins, P., Beule, D., Kettenmann, H. and Wolf, S.A.
Cell Reports 24 (10): 2773-2783. 4 September 2018

Therapeutic intranasal vaccine HB-ATV-8 prevents atherogenesis and non-alcoholic fatty liver disease in a pig model of atherosclerosis.
Gutiérrez-Vidal, R., Delgado-Coello, B., Méndez-Acevedo, K.M., Calixto-Tlacomulco, S., Damián-Zamacona, S. and Mas-Oliva, J.
Archives of Medical Research 49 (7): 456-470. October 2018

Metabolic barriers to weight gain in patients with anorexia nervosa: a young adult case report.
Haas, V., Stengel, A., Mähler, A., Gerlach, G., Lehmann, C., Boschmann, M., de Zwaan, M. and Herpertz, S.
Frontiers in Psychiatry 9 : 199. May 2018

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors.
Haghverdi, L., Lun, A.T.L., Morgan, M.D. and Marioni, J.C.
Nature Biotechnology 36 (5): 421-427. May 2018

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.
Hammer, Q., Rückert, T., Borst, E.M., Dunst, J., Haubner, A., Durek, P., Heinrich, F., Gasparoni, G., Babic, M., Tomic, A., Pietra, G., Nienen, M., Blau, I.W., Hofmann, J., Na, I.K., Prinz, I., Koenecke, C., Hemmati, P., Babel, N., Arnold, R., Walter, J., Thurley, K., Mashreghi, M.F., Messerle, M. and Romagnani, C.
Nature Immunology 19 (5): 453-463. May 2018

Efficacy of high-frequency repetitive transcranial magnetic stimulation on PANSS factors in schizophrenia with predominant negative symptoms - results from an exploratory re-analysis.
Hansbauer, M., Wobrock, T., Kunze, B., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Cordes, J., Wölwer, W., Winterer, G., Gaebel, W., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Malchow, B., Strube, W., Schneider-Axmann, T., Falkai, P. and Hasan, A.
Psychiatry Research 263 : 22-29. May 2018

FunImageJ: a lisp framework for scientific image processing.
Harrington, K.I.S., Rueden, C.T. and Eliceiri, K.W.
Bioinformatics 34 (5): 899-900. 1 March 2018

Caveolae link Ca(V)3.2 channels to BK(Ca)-mediated feedback in vascular smooth muscle.
Hashad, A.M., Harraz, O.F., Brett, S.E., Romero, M., Kassmann, M., Puglisi, J.L., Wilson, S.M., Gollasch, M. and Welsh, D.G.
Arteriosclerosis Thrombosis and Vascular Biology 38 (10): 2371-2381. October 2018

Pro-inflammatory monocyte phenotype and cell-specific steroid signaling alterations in unmedicated patients with major depressive disorder.
Hasselmann, H., Gamradt, S., Taenzer, A., Nowacki, J., Zain, R., Patas, K., Ramien, C., Paul, F., Wingenfeld, K., Piber, D., Gold, S.M. and Otte, C.
Frontiers in Immunology 9 : 2693. November 2018

Gene panel testing of 5589 BRCA1/2-negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian Cancer.
Hauke, J., Horvath, J., Groß, E., Gehrig, A., Honisch, E., Hackmann, K., Schmidt, G., Arnold, N., Faust, U., Sutter, C., Hentschel, J., Wang-Gohrke, S., Smogavec, M., Weber, B.H.F., Weber-Lassalle, N., Weber-Lassalle, K., Borde, J., Ernst, C., Altmüller, J., Volk, A.E., Thiele, H., Hübbel, V., Nürnberg, P., Keupp, K., Versmold, B., Pohl, E., Kubisch, C., Grill, S., Paul, V., Herold, N., Lichey, N., Rhiem, K., Ditsch, N., Ruckert, C., Wappenschmidt, B., Auber, B., Rump, A., Niederacher, D., Haaf, T., Ramser, J., Dworniczak, B., Engel, C., Meindl, A., Schmutzler, R.K. and Hahnen, E.
Cancer Medicine 7 (4): 1349-1358. April 2018

NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes.
He, C., Hu, X., Weston, T.A., Jung, R.S., Heizer, P., Tu, Y., Ellison, R., Matsumoto, K., Gerhardt, H., Tontonoz, P., Fong, L.G., Young, S.G. and Jiang, H.
Biochemical and Biophysical Research Communications 504 (4): 899-902. 12 October 2018

Effect of candesartan and metoprolol on myocardial tissue composition during anthracycline treatment: the PRADA trial.
Heck, S.L., Gulati, G., Hoffmann, P., von Knobelsdorff-Brenkenhoff, F., Storås, T.H., Ree, A.H., Gravdehaug, B., Røsjø, H., Steine, K., Geisler, J., Schulz-Menger, J. and Omland, T.
European Heart Journal - Cardiovascular Imaging 19 (5): 544-552. 1 May 2018

Perceptions on the value of bodily functions in multiple sclerosis.
Heesen, C., Haase, R., Melzig, S., Poettgen, J., Berghoff, M., Paul, F., Zettl, U., Marziniak, M., Angstwurm, K., Kern, R., Ziemssen, T. and Stellmann, J.P.
Acta Neurologica Scandinavica 137 (3): 356-362. March 2018

Beyond the limbic system: disruption and functional compensation of large-scale brain networks in patients with anti-LGI1 encephalitis.
Heine, J., Prüss, H., Kopp, U.A., Wegner, F., Then Bergh, F., Münte, T., Wandinger, K.P., Paul, F., Bartsch, T. and Finke, C.
Journal of Neurology Neurosurgery and Psychiatry 89 (11): 1191-1199. November 2018

Preserved heart function after left ventricular pressure overload in adult mice subjected to neonatal cardiac hypoplasia.
Heinecke, K., Heuser, A., Blaschke, F., Jux, C., Thierfelder, L. and Drenckhahn, J.D.
Journal of Developmental Origins of Health and Disease 9 (1): 112-124. February 2018

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia.
Herling, C.D., Abedpour, N., Weiss, J., Schmitt, A., Jachimowicz, R.D., Merkel, O., Cartolano, M., Oberbeck, S., Mayer, P., Berg, V., Thomalla, D., Kutsch, N., Stiefelhagen, M., Cramer, P., Wendtner, C.M., Persigehl, T., Saleh, A., Altmüller, J., Nürnberg, P., Pallasch, C., Achter, V., Lang, U., Eichhorst, B., Castiglione, R., Schäfer, S.C., Büttner, R., Kreuzer, K.A., Reinhardt, H.C., Hallek, M., Frenzel, L.P. and Peifer, M.
Nature Communications 9 (1): 727. 20 February 2018

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice.
Hernandez-Miranda, L.R., Ibrahim, D.M., Ruffault, P.L., Larrosa, M., Balueva, K., Müller, T., de Weerd, W., Stolte-Dijkstra, I., Hostra, R.M.W., Brunet, J.F., Fortin, G., Mundlos, S. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 115 (51): 13021-13026. 18 December 2018

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.
Hernáez, B., Alonso-Lobo, J.M., Montanuy, I., Fischer, C., Sauer, S., Sigal, L., Sevilla, N. and Alcamí, A.
Nature Communications 9 (1): 5440. 21 December 2018

Erfassung inzidenter kardiovaskulärer und metabolischer Erkrankungen in epidemiologischen Kohortenstudien in Deutschland [Assessing incident cardiovascular and metabolic diseases in epidemiological cohort studies in Germany].
Herrmann, W.J., Weikert, C., Bergmann, M., Boeing, H., Katzke, V.A., Kaaks, R., Tiller, D., Greiser, K.H., Heier, M., Meisinger, C., Schmidt, C.O., Neuhauser, H., Heidemann, C., Jünger, C., Wild, P.S., Schramm, S.H., Jöckel, K.H., Dörr, M. and Pischon, T.
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 61 (4): 420-431. April 2018

Volatile organic compounds in the breath of oral candidiasis patients: a pilot study.
Hertel, M., Schuette, E., Kastner, I., Hartwig, S., Schmidt-Westhausen, A.M., Preissner, R., Paris, S. and Preissner, S.
Clinical Oral Investigations 22 (2): 721-731. March 2018

Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system.
Herz, K., Becker, A., Shi, C., Ema, M., Takahashi, S., Potente, M., Hesse, M., Fleischmann, B.K. and Wenzel, D.
Angiogenesis 21 (2): 349-361. May 2018

PAR-3 controls endothelial planar polarity and vascular inflammation under laminar flow.
Hikita, T., Mirzapourshafiyi, F., Barbacena, P., Riddell, M., Pasha, A., Li, M., Kawamura, T., Brandes, R.P., Hirose, T., Ohno, S., Gerhardt, H., Matsuda, M., Franco, C.A. and Nakayama, M.
EMBO Reports 19 (9): e45253. 1 September 2018

Embryos and embryonic stem cells from the white rhinoceros.
Hildebrandt, T.B., Hermes, R., Colleoni, S., Diecke, S., Holtze, S., Renfree, M.B., Stejskal, J., Hayashi, K., Drukker, M., Loi, P., Göritz, F., Lazzari, G. and Galli, C.
Nature Communications 9 (1): 2589. 4 July 2018

GRHL2 is required for collecting duct epithelial barrier function and renal osmoregulation.
Hinze, C., Ruffert, J., Walentin, K., Himmerkus, N., Nikpey, E., Tenstad, O., Wiig, H., Mutig, K., Yurtdas, Z.Y., Klein, J.D., Sands, J.M., Branchi, F., Schumann, M., Bachmann, S., Bleich, M. and Schmidt-Ott, K.M.
Journal of the American Society of Nephrology 29 (3): 857-868. March 2018

Expanding the map of protein-RNA interaction sites via cell fusion followed by PAR-CLIP.
Hinze, F., Drewe-Boss, P., Milek, M., Ohler, U., Landthaler, M. and Gotthardt, M.
RNA Biology 15 (3): 359-368. 4 March 2018

Unraveling the transcriptional regulation of TWIST1 in limb development.
Hirsch, N., Eshel, R., Bar Yaacov, R., Shahar, T., Shmulevich, F., Dahan, I., Levaot, N., Kaplan, T., Lupiáñez, D.G. and Birnbaum, R..
PLoS Genetics 14 (10): e1007738. 29 October 2018

Nontargeted identification of tracer incorporation in high-resolution mass spectrometry.
Hoffmann, F., Jaeger, C., Bhattacharya, A., Schmitt, C.A. and Lisec, J.
Analytical Chemistry 90 (12): 7253-7260. 19 June 2018

Efficient non-viral gene delivery into human hematopoietic stem cells by minicircle Sleeping Beauty transposon vectors.
Holstein, M., Mesa-Nuñez, C., Miskey, C., Almarza, E., Poletti, V., Schmeer, M., Grueso, E., Ordóñez Flores, J.C., Kobelt, D., Walther, W., Aneja, M.K., Geiger, J,, Bonig, H.B., Izsvák, Z., Schleef, M., Rudolph, C., Mavilio, F., Bueren, J.A., Guenechea, G. and Ivics, Z.
Molecular Therapy 26 (4): 1137-1153. 4 April 2018

Multisite de novo mutations in human offspring after paternal exposure to ionizing radiation.
Holtgrewe, M., Knaus, A., Hildebrand, G., Pantel, J.T., de los Santos, M.R., Neveling, K., Goldmann, J., Schubach, M., Jäger, M., Coutelier, M., Mundlos, S., Beule, D., Sperling, K. and Krawitz, P.M.
Scientific Reports 8 (1): 14611. 2 October 2018

A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety.
Hommers, L.G., Richter, J., Yang, Y., Raab, A., Baumann, C., Lang, K., Schiele, M.A., Weber, H., Wittmann, A., Wolf, C., Alpers, G.W., Arolt, V., Domschke, K., Fehm, L., Fydrich, T., Gerlach, A., Gloster, A.T., Hamm, A.O., Helbig-Lang, S., Kircher, T., Lang, T., Pané-Farré, C.A., Pauli, P., Pfleiderer, B., Reif, A., Romanos, M., Straube, B., Ströhle, A., Wittchen, H.U., Frantz, S., Ertl, G., Lohse, M.J., Lueken, U. and Deckert, J.
Translational Psychiatry 8 (1): 226. 19 October 2018

Genetic deletion of the Angiotensin-(1-7) receptor Mas leads a reduced ovulatory rate.
Honorato-Sampaio, K., Ferreira Andrade, R., Bader, M., de Souza Martins, A., Souza Santos, R.A. and Reis, A.M.
Peptides 107 : 83-88. September 2018

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D., Schön, C., Loddenkemper, C., Lohneis, P., Kühl, A.A., Sommermann, T., Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

Myocardial effective transverse relaxation time T(2)* is elevated in hypertrophic cardiomyopathy: a 7.0 T magnetic resonance imaging study.
Huelnhagen, T., Ku, M.C., Reimann, H.M., Serradas Duarte, T., Pohlmann, A., Flemming, B., Seeliger, E., Eichhorn, C., Ferrari, V.A., Prothmann, M., Schulz-Menger, J. and Niendorf, T.
Scientific Reports 8 (1): 3974. 5 March 2018

Duration of storage influences the hemoglobin rising effect of red blood cells in patients undergoing major abdominal surgery.
Hunsicker, O., Hessler, K., Krannich, A., Boemke, W., Braicu, I., Sehouli, J., Meyer, O., Pruß, A., Spies, C. and Feldheiser, A.
Transfusion 58 (8): 1870-1880. August 2018

Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: Comparison to chronic phencyclidine and MK-801.
Hámor, P.U., Šírová, J., Páleníček, T., Zaniewska, M., Bubeníková-Valešová, V. and Schwendt, M.
Pharmacology Biochemistry and Behavior 175 : 89-100. December 2018

Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy.
Iannotti, F.A., Pagano, E., Guardiola, O., Adinolfi, S., Saccone, V., Consalvi, S., Piscitelli, F., Gazzerro, E., Busetto, G., Carrella, D., Capasso, R., Puri, P.L., Minchiotti, G. and Di Marzo, V.
Nature Communications 9 (1): 3950. 27 September 2018

Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M., Karabacak, A., Glahs, A., Kolundzic, E., Hirsekorn, A., Carda, A., Tursun, B., Zinzen, R.P., Lacadie, S.A. and Ohler, U.
Nature Communications 9 (1): 4472. 26 October 2018

Effects of carvedilol versus metoprolol on platelet aggregation in patients with acute coronary syndrome: the PLATE-BLOCK study.
Ilardi, F., Gargiulo, G., Schiattarella, G.G., Giugliano, G., Paolillo, R., Menafra, G., De Angelis, E., Scudiero, L., Franzone, A., Stabile, E., Perrino, C., Cirillo, P., Morisco, C., Izzo, R., Trimarco, V. and Esposito, G.
American Journal of Cardiology 122 (1): 6-11. 1 July 2018

Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during mitosis.
Imami, K., Milek, M., Bogdanow, B., Yasuda, T., Kastelic, N., Zauber, H., Ishihama, Y., Landthaler, M. and Selbach, M.
Molecular Cell 72 (1): 84-98. 4 October 2018

Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: a comprehensive examination of the potential carriers for semiochemicals.
Iovinella, I., McAfee, A., Mastrobuoni, G., Kempa, S., Foster, L.J., Pelosi, P. and Dani, F.R.
Journal of Proteomics 181 : 131-141. 15 June 2018

Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations.
Irmak, D., Fatima, A., Gutiérrez-Garcia, R., Rinschen, M.M., Wagle, P., Altmüller, J., Arrigoni, L., Hummel, B., Klein, C., Frese, C.K., Sawarkar, R., Rada-Iglesias, A. and Vilchez, D.
Human Molecular Genetics 27 (23): 4117-4134. 1 December 2018

Rare gene deletions in genetic generalized and Rolandic epilepsies.
Jabbari, K., Bobbili, D.R., Lal, D., Reinthaler, E.M., Schubert, J., Wolking, S., Sinha, V., Motameny, S., Thiele, H., Kawalia, A., Altmüller, J., Toliat, M.R., Kraaij, R., van Rooij, J., Uitterlinden, A.G., Ikram, M.A., Zara, F., Lehesjoki, A.E., Krause, R., Zimprich, F., Sander, T., Neubauer, B.A., May, P., Lerche, H. and Nürnberg, P.
PLoS ONE 13 (8): e0202022. 27 August 2018

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Jacquelin, S., Straube, J., Cooper, L., Vu, T., Song, A., Bywater, M., Baxter, E., Heidecker, M., Wackrow, B., Porter, A., Ling, V., Green, J., Austin, R., Kazakoff, S., Waddell, N., Hesson, L.B., Pimanda, J.E., Stegelmann, F., Bullinger, L., Döhner, K., Rampal, R.K., Heckl, D., Hill, G.R. and Lane, S.W.
Blood 132 (26): 2707-2721. 27 December 2018

Human mesenchymal factors induce rat hippocampal- and human neural stem cell dependent oligodendrogenesis.
Jadasz, J.J., Tepe, L., Beyer, F., Samper Agrelo, I., Akkermann, R., Spitzhorn, L.S., Silva, M.E., Oreffo, R.O.C., Hartung, H.P., Prigione, A., Rivera, F.J., Adjaye, J. and Kuery, P.
Glia 66 (1): 145-160. January 2018

Variability and reliability study of overall physical activity and activity intensity levels using 24 h-accelerometry-assessed data.
Jaeschke, L., Steinbrecher, A., Jeran, S., Konigorski, S. and Pischon, T.
BMC Public Health 18 (1): 530. 20 April 2018

Characterization of hyperbranched core-multishell nanocarriers as an innovative drug delivery system for the application at the oral mucosa.
Jager, J., Obst, K., Lohan, S.B., Viktorov, J., Staufenbiel, S., Renz, H., Unbehauen, M., Haag, R., Hedtrich, S., Teutloff, C., Meinke, M..C., Danker, K. and Dommisch, H.
Journal of periodontal research 53 (1): 57-65. February 2018

Baló's concentric sclerosis is immunologically distinct from multiple sclerosis: results from retrospective analysis of almost 150 lumbar punctures.
Jarius, S., Würthwein, C., Behrens, J.R., Wanner, J., Haas, J., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 15 (1): 22. 18 January 2018

High peak and high average radiofrequency power transmit/receive switch for thermal magnetic resonance.
Ji, Y., Hoffmann, W., Pham, M., Dunn, A.E., Han, H., Özerdem, C., Waiczies, H., Rohloff, M., Endemann, B., Boyer, C., Lim, M., Niendorf, T. and Winter, L.
Magnetic Resonance in Medicine 80 (5): 2246-2255. November 2018

Gut microbiota composition is associated with environmental landscape in honey bees.
Jones, J.C., Fruciano, C., Hildebrand, F., Al Toufalilia, H., Balfour, N.J., Bork, P., Engel, P., Ratnieks, F.L.W. and Hughes, W.O.H.
Ecology and Evolution 8 (1): 441-451. January 2018

The gut microbiome is associated with behavioural task in honey bees.
Jones, J.C., Fruciano, C., Marchant, J., Hildebrand, F., Forslund, S., Bork, P., Engel, P. and Hughes, W.O.H.
Insectes Sociaux 65 (3): 419-429. August 2018

Long noncoding RNA lISPR1 is required for S1P signaling and endothelial cell function.
Josipovic, I., Pflueger, B., Fork, C., Vasconez, A.E., Oo, J.A., Hitzel, J., Seredinski, S., Gamen, E., Heringdorf, D.M.Z., Chen, W., Looso, M., Pullamsetti, S.S., Brandes, R.P. and Leisegang, M.S.
Journal of Molecular and Cellular Cardiology 116 : 57-68. March 2018

Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo.
Jouhanneau, J.S., Kremkow, J. and Poulet, J.F.A.
Nature Communications 9 (1): 1540. 18 April 2018

K(2P) TASK-2 and KCNQ1/KCNE3 K(+) channels are major players contributing to intestinal anion and fluid secretion.
Julio-Kalajzić, F., Villanueva, S., Burgos, J., Ojeda, M., Cid, L.P., Jentsch, T.J. and Sepúlveda, F.V.
Journal of Physiology 596 (3): 393-407. 1 February 2018

Crystal structures of the single PDZ domains from GRASP65 and their interaction with the golgin GM130.
Jurk, C.M., Roske, Y. and Heinemann, U.
Croatica Chemica Acta 91 (2): 255-264. June 2018

Chromatin accessibility dynamics across C. elegans development and ageing.
Jänes, J., Dong, Y., Schoof, M., Serizay, J., Appert, A., Cerrato, C., Woodbury, C., Chen, R., Gemma, C., Huang, N., Kissiov, D., Stempor, P., Steward, A., Zeiser, E., Sauer, S. and Ahringer, J.
eLife 7 : e37344. 26 October 2018

Agonistic autoantibodies to the β2-adrenergic receptor involved in the pathogenesis of open-angle glaucoma.
Jünemann, A., Hohberger, B., Rech, J., Sheriff, A., Fu, Q., Schlötzer-Schrehardt, U., Voll, R.E., Bartel, S., Kalbacher, H., Hoebeke, J., Rejdak, R., Horn, F., Wallukat, G., Kunze, R. and Herrmann, M.
Frontiers in Immunology 9 : 145. 12 February 2018

Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.
Kabrani, E., Chu, V.T., Tasouri, E., Sommermann, T., Baßler, K., Ulas, T., Zenz, T., Bullinger, L., Schultze, J.L., Rajewsky, K. and Sander, S.
Blood 132 (25): 2670-2683. 20 December 2018

PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells.
Kahn, J.D., Miller, P.G., Silver, A.J., Sellar, R.S., Bhatt, S., Gibson, C., McConkey, M., Adams, D., Mar, B., Mertins, P., Fereshetian, S., Krug, K., Zhu, H., Letai, A., Carr, S.A., Doench, J., Jaiswal, S. and Ebert, B.L.
Blood 132 (11): 1095-1105. 13 September 2018

The influence of capsaicin on the integrity of microvascular endothelial cell monolayers.
Kaiser, M., Burek, M., Britz, S., Lankamp, F., Ketelhut, S., Kemper, B., Förster, C., Gorzelanny, C. and Goycoolea, F.M.
International Journal of Molecular Sciences 20 (1): 122. 30 December 2018

OR2H2 regulates the differentiation of human myoblast cells by its ligand aldehyde 13-13.
Kalbe, B., Osterloh, M., Schulz, V.M., Altmüller, J., Becker, C., Osterloh, S. and Hatt, H.
Archives of Biochemistry and Biophysics 645 : 72-80. 1 May 2018

A novel RNA editing sensor tool and a specific agonist determine neuronal protein expression of RNA-edited glycine receptors and identify a genomic APOBEC1 dimorphism as a new genetic risk factor of epilepsy.
Kankowski, S., Förstera, B., Winkelmann, A., Knauff, P., Wanker, E.E., You, X.A., Semtner, M., Hetsch, F. and Meier, J.C.
Frontiers in Molecular Neuroscience 10 : 439. 11 January 2018

Mast cells and serotonin synthesis modulate Chagas disease in the colon: clinical and experimental evidence.
Kannen, V., Sakita, J.Y., Carneiro, Z.A., Bader, M., Alenina, N., Teixeira, R.R., de Oliveira, E.C., Brunaldi, M.O., Gasparotto, B., Sartori, D.C., Fernandes, C.R., Silva, J.S., Andrade, M.V., Silva, W.A., Uyemura, S.A. and Garcia, S.B.
Digestive Diseases and Sciences 63 (6): 1473-1484. June 2018

The association between brain volume, cortical brain infarcts, and physical frailty.
Kant, I.M.J., de Bresser, J., van Montfort, S.J.T., Aarts, E., Verlaan, J.J., Zacharias, N., Winterer, G., Spies, C., Slooter, A.J.C. and Hendrikse, J.
Neurobiology of Aging 70 : 247-253. October 2018

A single-cell transcriptome atlas of the mouse glomerulus.
Karaiskos, N., Rahmatollahi, M., Boltengagen, A., Liu, H., Hoehne, M., Rinschen, M., Schermer, B., Benzing, T., Rajewsky, N., Kocks, C., Kann, M. and Müller, R.U.
Journal of the American Society of Nephrology 29 (8): 2060-2068. August 2018

Targeted sequencing with expanded gene profile enables high diagnostic yield in non-5q-spinal muscular atrophies.
Karakaya, M., Storbeck, M., Strathmann, E.A., Delle Vedove, A., Hölker, I., Altmueller, J., Naghiyeva, L., Schmitz-Steinkrüger, L., Vezyroglou, K., Motameny, S., Alawbathani, S., Thiele, H., Polat, A.I., Okur, D., Boostani, R., Karimiani, E.G., Wunderlich, G., Ardicli, D., Topaloglu, H., Kirschner, J., Schrank, B., Maroofian, R., Magnusson, O., Yis, U., Nürnberg, P., Heller, R. and Wirth, B.
Human Mutation 39 (9): 1284-1298. September 2018

Role of alpha1-adrenergic receptor antibodies in Alzheimer's disease.
Karczewski, P., Hempel, P. and Bimmler, M.
Frontiers in Bioscience 23 : 2082-2089. 1 June 2018

High-salt diet causes expansion of the lymphatic network and increased lymph flow in skin and muscle of rats.
Karlsen, T.V., Nikpey, E., Han, J., Reikvam, T., Rakova, N., Castorena-Gonzalez, J.A., Davis, M.J., Titze, J.M., Tenstad, O. and Wiig, H.
Arteriosclerosis Thrombosis and Vascular Biology 38 (9): 2054-2064. September 2018

Whole exome sequencing identifies a mutation in EYA1 and GLI3 in a patient with branchio‑otic syndrome and esophageal atresia: Coincidence or a digenic mode of inheritance?
Kause, F., Reutter, H., Marsch, F., Thiele, H., Altmüller, J., Ludwig, M. and Zhang, R.
Molecular Medicine Reports 17 (2): 3200-3205. February 2018

Nuclear pore complex components in the malaria parasite Plasmodium berghei.
Kehrer, J., Kuss, C., Andres-Pons, A., Reustle, A., Dahan, N., Devos, D., Kudryashev, M., Beck, M., Mair, G.R. and Frischknecht, F.
Scientific Reports 8 (1): 11249. 26 July 2018

Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis.
Khajuria, R.K., Munschauer, M., Ulirsch, J.C., Fiorini, C., Ludwig, L.S., McFarland, S.K., Abdulhay, N.J., Specht, H., Keshishian, H., Mani, D.R., Jovanovic, M., Ellis, S.R., Fulco, C.P., Engreitz, J.M., Schütz, S., Lian, J., Gripp, K.W., Weinberg, O.K., Pinkus, G.S., Gehrke, L., Regev, A., Lander, E.S., Gazda, H.T., Lee, W.Y., Panse, V.G., Carr, S.A. and Sankaran, V.G.
Cell 173 (1): 90-103. 22 March 2018

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M., Wende, H., Walcher, J., Kühnemund, J., Cheret, C., Kempa, S., McShane, E., Selbach, M., Lewin, G.R. and Birchmeier, C.
Genes & Development 32 (9-10): 645-657. 10 May 2018

Guidelines for training in cardiovascular magnetic resonance (CMR).
Kim, R.J., Simonetti, O.P., Westwood, M., Kramer, C.M., Narang, A., Friedrich, M.G., Powell, A.J., Carr, J.C., Schulz-Menger, J., Nagel, E., Chan, W.S., Bremerich, J., Ordovas, K.G., Rollings, R.C., Patel, A.R. and Ferrari, V.A.
Journal of Cardiovascular Magnetic Resonance 20 (1): 57. 16 August 2018

Racial differences in neuromyelitis optica spectrum disorder.
Kim, S.H., Mealy, M.A., Levy, M., Schmidt, F., Ruprecht, K., Paul, F., Ringelstein, M., Aktas, O., Hartung, H.P., Asgari, N., Tsz-Ching, J.L., Siritho, S., Prayoonwiwat, N., Shin, H.J., Hyun, J.W., Han, M., Leite, M.I., Palace, J. and Kim, H.J.
Neurology 91 (22): e2089-e2099. 27 November 2018

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway.
Klein, W., Rutz, C., Eckhard, J., Provinciael, B., Specker, E., Neuenschwander, M., Kleinau, G., Scheerer, P., von Kries, J.P., Nazaré, M., Vermeire, K. and Schülein, R.
PLoS ONE 13 (12): e0208641. 13 December 2018

S1P signalling differentially affects migration of peritoneal B cell populations in vitro and influences the production of intestinal IgA in vivo.
Kleinwort, A., Luehrs, F., Heidecke, C.D., Lipp, M. and Schulze, T.
International Journal of Molecular Sciences 19 (2): 391. 29 January 2018

Apheresis therapies for NMOSD attacks: a retrospective study of 207 therapeutic interventions.
Kleiter, I., Gahlen, A., Borisow, N., Fischer, K., Wernecke, K.D., Hellwig, K., Pache, F., Ruprecht, K., Havla, J., Kümpfel, T., Aktas, O., Hartung, H.P., Ringelstein, M., Geis, C., Kleinschnitz, C., Berthele, A., Hemmer, B., Angstwurm, K., Stellmann, J.P., Schuster, S., Stangel, M., Lauda, F., Tumani, H., Mayer, C., Krumbholz, M., Zeltner, L., Ziemann, U., Linker, R., Schwab, M., Marziniak, M., Then Bergh, F., Hofstadt-van Oy, U., Neuhaus, O., Zettl, U.K., Faiss, J., Wildemann, B., Paul, F., Jarius, S. and Trebst, C.
Neurology Neuroimmunology & Neuroinflammation 5 (6): e504. November 2018

Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response.
Klempin, F., Mosienko, V., Matthes, S., Villela, D.C., Todiras, M., Penninger, J.M., Bader, M., Santos, R.A.S. and Alenina, N.
Cellular and Molecular Life Sciences 75 (19): 3625-3634. October 2018

Normobaric hypoxic conditioning in men with metabolic syndrome.
Klug, L., Mähler, A., Rakova, N., Mai, K., Schulz-Menger, J., Rahn, G., Busjahn, A., Jordan, J., Boschmann, M. and Luft, F.C.
Physiological Reports 6 (24): e13949. December 2018

Oral administration of a novel lipophilic PPARδ agonist is not neuroprotective after rodent cerebral ischemia.
Knauss, S., Endres, M., Blaschke, F., Hindinger, C. and Kunz, A.
Journal of Cerebral Blood Flow and Metabolism 38 (1): 174-185. 1 January 2018

Structural investigation of glycan recognition by the ERAD quality control lectin Yos9.
Kniss, A., Kazemi, S., Löhr, F., Berger, M., Rogov, V.V., Güntert, P., Sommer, T., Jarosch, E. and Dötsch, V.
Journal of Biomolecular NMR 72 (1-2): 1-10. October 2018

Chain assembly and disassembly processes differently affect the conformational space of ubiquitin chains.
Kniss, A., Schuetz, D., Kazemi, S., Pluska, L., Spindler, P.E., Rogov, V.V., Husnjak, K., Dikic, I., Güntert, P., Sommer, T., Prisner, T.F. and Dötsch, V.
Structure 26 (2): 249-258. 6 February 2018

Single-molecule fluorescence in situ hybridization (FISH) of circular RNA CDR1as.
Kocks, C., Boltengagen, A., Piwecka, M., Rybak-Wolf, A. and Rajewsky, N.
Methods in Molecular Biology 1724 : 77-96. 2018

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E., Ofenbauer, A., Bulut, S.I., Uyar, B., Baytek, G., Sommermeier, A., Seelk, S., He, M., Hirsekorn, A., Vucicevic, D., Akalin, A., Diecke, S., Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

Application of RNAi and heat-shock-induced transcription factor expression to reprogram germ cells to neurons in C. elegans.
Kolundzic, E., Seelk, S. and Tursun, B.
Journal of Visualized Experiments (131): e56889. 1 January 2018

Estimating and testing direct genetic effects in directed acyclic graphs using estimating equations.
Konigorski, S., Wang, Y., Cigsar, C. and Yilmaz, Y.E.
Genetic Epidemiology 42 (2): 174-186. March 2018

Autologous iPSC-based vaccines elicit anti-tumor responses in vivo.
Kooreman, N.G., Kim, Y., de Almeida, P.E., Termglinchan, V., Diecke, S., Shao, N.Y., Wei, T.T., Yi, H., Dey, De., Nelakanti, R., Brouwer, T.P., Paik, D.T., Sagiv-Barfi, I., Han, A., Quax, P.H.A., Hamming, J.F., Levy, R., Davis, M.M. and Wu, J.C.
Cell Stem Cell 22 (4): 501-513. 5 April 2018

Elevated tissue sodium deposition in patients with type 2 diabetes on hemodialysis detected by (23)Na magnetic resonance imaging.
Kopp, C., Linz, P., Maier, C., Wabel, P., Hammon, M., Nagel, A.M., Rosenhauer, D., Horn, S., Uder, M., Luft, F.C., Titze, J. and Dahlmann, A.
Kidney International 93 (5): 1191-1197. May 2018

Loss of pten and activation of kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice.
Kopp, J.L., Dubois, C.L., Schaeffer, D.F., Samani, A., Taghizadeh, F., Cowan, R.W., Rhim, A.D., Stiles, B.L., Valasek, M. and Sander, M.
Gastroenterology 154 (5): 1509-1523.e5. April 2018

Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - The THYROID Project.
Kopp, S., Krüger, M., Feldmann, S., Oltmann, H., Schütte, A., Schmitz, B., Bauer, J., Schulz, H., Saar, K., Hübner, N., Wehland, M., Nassef, M.Z., Melnik, D., Meltendorf, S., Infanger, M. and Grimm, D.
Scientific Reports 8 (1): 10355. 9 July 2018

The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine.
Kopp, S., Sahana, J., Islam, T., Petersen, A.G., Bauer, J., Corydon, T.J., Schulz, H., Saar, K., Huebner, N., Slumstrup, L., Riwaldt, S., Wehland, M., Infanger, M., Luetzenberg, R. and Grimm, D.
Scientific Reports 8 (1): 921. 17 January 2018

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.
Koren, E., Yosefzon, Y., Ankawa, R., Soteriou, D., Jacob, A., Nevelsky, A., Ben-Yosef, R., Bar-Sela, G. and Fuchs, Y.
Nature Communications 9 (1): 4582. 2 November 2018

Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease.
Kork, F., Jankowski, J., Goswami, A., Weis, J., Brook, G., Yamoah, A., Anink, J., Aronica, E., Fritz, S., Huck, C., Schipke, C., Peters, O., Tepel, M., Noels, H. and Jankowski, V.
Neurology 91 (19): e1799-e1808. 6 November 2018

Selective maternal seeding and environment shape the human gut microbiome.
Korpela, K., Costea, P., Coelho, L.P., Kandels-Lewis, S., Willemsen, G., Boomsma, D.I., Segata, N. and Bork, P.
Genome Research 28 (4): 561-568. April 2018

Predicting response to repetitive transcranial magnetic stimulation in patients with schizophrenia using structural magnetic resonance imaging: a multisite machine learning analysis.
Koutsouleris, N., Wobrock, T., Guse, B., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Cordes, J., Woelwer, W., Musso, F., Winterer, G., Gaebel, W., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Dwyer, D., Ghaseminejad, F., Dechent, P., Malchow, B., Kreuzer, P.M., Poeppl, T.B., Schneider-Axmann, T., Falkai, P. and Hasan, A.
Schizophrenia Bulletin 44 (5): 1021-1034. 20 August 2018

MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
Kozlowski, M., Corujo, D., Hothorn, M., Guberovic, I., Mandemaker, I.K., Blessing, C., Sporn, J., Gutierrez-Triana, A., Smith, R., Portmann, T., Treier, M., Scheffzek, K., Huet, S., Timinszky, G., Buschbeck, M. and Ladurner, A.G.
EMBO Reports 19 (10): e44445. 1 October 2018

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis.
Kragesteen, B.K., Spielmann, M., Paliou, C., Heinrich, V., Schöpflin, R., Esposito, A., Annunziatella, C., Bianco, S., Chiariello, A.M., Jerković, I., Harabula, I., Guckelberger, P., Pechstein, M., Wittler, L., Chan, Wi.L., Franke, M., Lupiáñez, D.G., Kraft, K., Timmermann, B., Vingron, M., Visel, A., Nicodemi, M., Mundlos, S. and Andrey, G.
Nature Genetics 50 (10): 1463-1473. October 2018

Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas.
Kratzsch, T., Kuhn, S.A., Joedicke, A., Hanisch, U.K., Vajkoczy, P., Hoffmann, J. and Fichtner, I.
Journal of Cancer Research and Clinical Oncology 144 (5): 809-819. May 2018

The role of PAR1 autoantibodies in patients with primary epithelial ovarian cancer.
Kreienbring, K., Franz, A., Richter, R., Dragun, D., Heidecke, H., Müller, D., Mentze, M., Dechend, R., Sehouli, J. and Braicu, E.I.
Anticancer Research 38 (6): 3619-3625. June 2018

NF-κB participates in mouse hair cycle control and plays distinct roles in the various pelage hair follicle types.
Krieger, K., Millar, S.E., Mikuda, N., Krahn, I., Kloepper, J.E., Bertolini, M., Scheidereit, C., Paus, R. and Schmidt-Ullrich, R.
Journal of Investigative Dermatology 138 (2): 256-264. February 2018

Brain serotonin critically contributes to the biological effects of electroconvulsive seizures.
Kronenberg, G., Petermann, M., Dormann, C., Bader, M., Gass, P., Hellweg, R. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 268 (8): 861-864. December 2018

Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G., Uhlemann, R., Richter, N., Klempin, F., Wegner, S., Staerck, L., Wolf, S., Uckert, W., Kettenmann, H., Endres, M. and Gertz, K.
Acta Neuropathologica 135 (4): 551. April 2018

Cardiac MRI in small animals.
Ku, M.C., Huelnhagen, T., Niendorf, T. and Pohlmann, A.
Methods in Molecular Biology 1718 : 269-284. 2018

Assessment of blood brain barrier leakage with gadolinium-enhanced MRI.
Ku, M.C., Waiczies, S., Niendorf, T. and Pohlmann, A.
Methods in Molecular Biology 1718 : 395-408. 2018

Comparison of probabilistic tractography and tract-based spatial statistics for assessing optic radiation damage in patients with autoimmune inflammatory disorders of the central nervous system.
Kuchling, J., Backner, Y., Oertel, F.C., Raz, N., Bellmann-Strobl, J., Ruprecht, K., Paul, F., Levin, N., Brandt, A.U. and Scheel, M.
NeuroImage: Clinical 19 : 538-550. 8 May 2018

Nrf2-mediated antioxidant defense and peroxiredoxin 6 are linked to biosynthesis of palmitic acid ester of 9-hydroxystearic acid.
Kuda, O., Brezinova, M., Silhavy, J., Landa, V., Zidek, V., Dodia, C., Kreuchwig, F., Vrbacky, M., Balas, L., Durand, T., Hübner, N., Fisher, A.B., Kopecky, J. and Pravenec, M.
Diabetes 67 (6): 1190-1199. June 2018

Solvent networks tune thermodynamics of oligosaccharide complex formation in an extended protein binding site.
Kunstmann, S., Gohlke, U., Broeker, N.K., Roske, Y., Heinemann, U., Santer, M. and Barbirz, S.
Journal of the American Chemical Society 140 (33): 10447-10455. 22 August 2018

Metagenomic analysis of gut microbial communities from a Central Asian population.
Kushugulova, A., Forslund, S.K., Costea, P.I., Kozhakhmetov, S., Khassenbekova, Z., Urazova, M., Nurgozhin, T., Zhumadilov, Z., Benberin, V., Driessen, M., Hercog, R., Voigt, A.Y., Benes, V., Kandels-Lewis, S., Sunagawa, S., Letunic, I. and Bork, P.
BMJ Open 8 (7): e021682. 28 July 2018

Antihypertensive treatment patterns and blood pressure control in older adults: results from the Berlin Aging Study II.
König, M., Gollasch, M., Rosada, A., Demuth, I., Spira, D. and Steinhagen-Thiessen, E.
Drugs & Aging 35 (11): 993-1003. November 2018

Mild-to-moderate chronic kidney disease and geriatric outcomes: analysis of cross-sectional data from the Berlin Aging Study II.
König, M., Gollasch, M., Spira, D., Buchmann, N., Hopfenmüller, W., Steinhagen-Thiessen, E. and Demuth, I.
Gerontology 64 (2): 118-126. February 2018

MYC-containing amplicons in acute myeloid leukemia: genomic structures, evolution, and transcriptional consequences.
L'Abbate, A., Tolomeo, D., Cifola, I., Severgnini, M., Turchiano, A., Augello, B., Squeo, G., D'Addabbo, P., Traversa, D., Daniele, G., Lonoce, A., Pafundi, M., Carella, M., Palumbo, O., Dolnik, A., Muehlematter, D., Schoumans, J., Van Roy, N., De Bellis, G., Martinelli, G., Merla, G., Bullinger, L., Haferlach, C. and Storlazzi, C.T.
Leukemia 32 (10): 2152-2166. October 2018

DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.
La Fortezza, M., Grigolon, G., Cosolo, A., Pindyurin, A., Breimann, L., Blum, H., van Steensel, B. and Classen, A.K.
Epigenetics & Chromatin 11 (1): 27. 5 June 2018

HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.
LaBranche, C.C., McGuire, A.T., Gray, M.D., Behrens, S., Chen, X., Zhou, T., Sattentau, Q.J., Peacock, J., Eaton, A., Greene, K., Gao, H., Tang, H., Perez, L.G., Saunders, K.O., Kwong, P.D., Mascola, J.R., Haynes, B.F., Stamatatos, L. and Montefiori, D.C.
PLoS Pathogens 14 (11): e1007431. 5 November 2018

Diabetes, but not hypertension and obesity, is associated with postoperative cognitive dysfunction.
Lachmann, G., Feinkohl, I., Borchers, F., Ottens, T.H., Nathoe, H.M., Sauer, A.M., Dieleman, J.M., Radtke, F.M., van Dijk, D., Spies, C. and Pischon, T.
Dementia and Geriatric Cognitive Disorders 46 (3-4): 193-206. 16 October 2018

Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs).
Lagies, S., Pichler, R., Kaminski, M.M., Schlimpert, M., Walz, G., Lienkamp, S.S. and Kammerer, B.
Scientific Reports 8 (1): 3878. 1 March 2018

Basal forebrain cholinergic system volume is associated with general cognitive ability in the elderly.
Lammers, F., Borchers, F., Feinkohl, I., Hendrikse, J., Kant, I.M.J., Kozma, P., Pischon, T., Slooter, A.J.C., Spies, C., van Montfort, S.J.T., Zacharias, N., Zaborszky, L. and Winterer, G.
Neuropsychologia 119 : 145-156. October 2018

Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates.
Langer, H.T., Senden, J.M.G., Gijsen, A.P., Kempa, S., van Loon, Luc J. C. and Spuler, S.
Frontiers in Physiology 9 : 1220. 31 August 2018

The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice.
Langhorst, H., Jüttner, R., Groneberg, D., Mohtashamdolatshahi, A., Pelz, L., Purfürst, B., Schmidt-Ott, K.M., Friebe, A. and Rathjen, F.G.
Disease Models & Mechanisms 11 (2): dmm032128. 22 February 2018

The biotrophic development of Ustilago maydis studied by RNA-seq analysis.
Lanver, D., Müller, A.N., Happel, P., Schweizer, G., Haas, F.B., Franitza, M., Pellegrin, C., Reissmann, S., Altmüller, J., Rensing, S.A. and Kahmann, R.
Plant Cell 30 (2): 300-323. February 2018

Size matters: grey matter brain reserve predicts executive functioning in the elderly.
Laubach, M., Lammers, F., Zacharias, N., Feinkohl, I., Pischon, T., Borchers, F, Slooter, A.J.C., Kühn, S., Spies, C. and Winterer, G.
Neuropsychologia 119 : 172-181. October 2018

Characterization of transcription termination-associated RNAs: new insights into their biogenesis, tailing, and expression in primary tumors.
Laudadio, I., Formichetti, S., Gioiosa, S., Klironomos, F., Rajewsky, N., Macino, G., Carissimi, C. and Fulci, V.
International Journal of Genomics 2018 : 1243858. 26 April 2018

mVOC 2.0: a database of microbial volatiles.
Lemfack, M.C., Gohlke, B.O., Toguem, S.M.T., Preissner, S., Piechulla, B. and Preissner, R.
Nucleic Acids Research 46 (D1): D1261-D1265. 4 January 2018

Warum die Deutsche Gesellschaft für Neurologie einen industrieunabhängigen Kongress braucht [Why German neurology needs an annual meeting without industry sponsorship].
Lempert, T., Janzen, R., Diehl, R., Stark, E., Paul, F., Wilke, C., Tavakolian, R., Völzke, E., von Brevern, M. and Möller, P.
Aktuelle Neurologie 45 (6): 429-433. August 2018

Integrating HDAd5/35++ vectors as a new platform for HSC gene therapy of hemoglobinopathies.
Li, C., Psatha, N., Wang, H., Singh, M., Samal, H.B., Zhang, W., Ehrhardt, A., Izsvák, Z., Papayannopoulou, T. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 9 : 142-152. 15 June 2018

Conditional deletion of FOXL2 and SMAD4 in gonadotropes of adult mice causes isolated FSH deficiency.
Li, Y., Schang, G., Wang, Y., Zhou, X., Levasseur, A., Boyer, A., Deng, C.X., Treier, M., Boehm, U., Boerboom, D. and Bernard, D.J.
Endocrinology 159 (7): 2641-2655. 1 July 2018

RXFP1 receptor activation by relaxin-2 induces vascular relaxation in mice via a Gα(i2)-protein/PI3Kß/γ/nitric oxide-coupled pathway.
Lian, X., Beer-Hammer, S., König, G.M., Kostenis, E., Nürnberg, B. and Gollasch, M.
Frontiers in Physiology 9 : 1234. September 2018

Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill.
Lin, X., Noel, J.K., Wang, Q., Ma, J. and Onuchic, J.N.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): E7905-E7913. 21 August 2018

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling.
Liss, M., Radke, M.H., Eckhard, J., Neuenschwander, M., Dauksaite, V., von Kries, J.P. and Gotthardt, M.
PLoS ONE 13 (6): e0198492. 11 June 2018

Structural basis for membrane tethering by a bacterial dynamin-like pair.
Liu, J., Noel, J.K. and Low, H.H.
Nature Communications 9 (1): 3345. 21 August 2018

A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging.
Liu, Y., Zhang, L., Nazare, M., Yao, Q. and Hu, H.Y.
Acta Pharmaceutica Sinica B 8 (3): 401-408. May 2018

Transient N-6-methyladenosine transcriptome sequencing reveals a regulatory role of m6A in splicing efficiency.
Louloupi, A., Ntini, E., Conrad, T. and Ørom, U.A.V.
Cell Reports 23 (12): 3429-3437. 19 June 2018

Circular RNAs in cancer.
Lux, S. and Bullinger, L.
Advances in Experimental Medicine and Biology 1087 : 215-230. 28 September 2018

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.
Löber, U., Hobbs, M., Dayaram, A., Tsangaras, K., Jones, K., Alquezar-Planas, D.E., Ishida, Y., Meers, J., Mayer, J., Quedenau, C., Chen, W., Johnson, R.N., Timms, P., Young, P.R., Roca, A.L. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): 8609-8614. 21 August 2018

Generation of full-thickness skin equivalents using hair follicle-derived primary human keratinocytes and fibroblasts.
Löwa, A., Vogt, A., Kaessmeyer, S. and Hedtrich, S.
Journal of Tissue Engineering and Regenerative Medicine 12 (4): e2134-e2146. April 2018

LRRC8/VRAC anion channels are required for late stages of spermatid development in mice.
Lück, J.C., Puchkov, D., Ullrich, F. and Jentsch, T.J.
Journal of Biological Chemistry 293 (30): 11796-11808. 27 July 2018

Pathway analysis hints towards beneficial effects of long-term vibration on human chondrocytes.
Lützenberg, R., Solano, K., Buken, C., Sahana, J., Riwaldt, S., Kopp, S., Krüger, M., Schulz, H., Saar, K., Huebner, N., Hemmersbach, R., Bauer, J., Infanger, M., Grimm, D. and Wehland, M.
Cellular Physiology and Biochemistry 47 (4): 1729-1741. 28 June 2018

Shearlet-based compressed sensing for fast 3D cardiac MR imaging using iterative reweighting.
Ma, J., März, M., Funk, S., Schulz-Menger, J., Kutyniok, G., Schaeffter, T. and Kolbitsch, C.
Physics in Medicine and Biology 63 (23): 235004. 22 November 2018

Reorganization of inter-chromosomal interactions in the 2q37-deletion syndrome.
Maass, P.G., Weise, A., Rittscher, K., Lichtenwald, J., Barutcu, A.R., Liehr, T., Aydin, A., Wefeld-Neuenfeld, Y., Pölsler, L., Tinschert, S., Rinn, J.L., Luft, F.C. and Bähring, S.
EMBO Journal 37 (15): e96257. 1 August 2018

Soluble B7-H4 blood serum levels are elevated in women at high risk for preeclampsia in the first trimester, as well as in patients with confirmed preeclampsia.
Mach, P., Nolte-Boenigk, L., Droste, L., Fox, L., Frank, M., Schmidt, B., Herse, F., Verlohren, S., Wicherek, L., Iannaccone, A., Birdir, C., Andrikos, D., Kimmig, R., Gellhaus, A. and Köninger, A.
American Journal of Reproductive Immunology 80 (3): e12988. September 2018

Extensive impact of non-antibiotic drugs on human gut bacteria.
Maier, L., Pruteanu, M., Kuhn, M., Zeller, G., Telzerow, A., Anderson, E.E., Brochado, A.R., Fernandez, K.C., Dose, H., Mori, H., Patil, K.R., Bork, P. and Typas, A.
Nature 555 (7698): 623-628. 29 March 2018

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Maifrede, S., Nieborowska-Skorska, M., Sullivan-Reed, K., Dasgupta, Y., Podszywalow-Bartnicka, P., Le, B.V., Solecka, M., Lian, Z., Belyaeva, E.A., Nersesyan, A., Machnicki, M.M., Toma, M., Chatain, N., Rydzanicz, M., Zhao, H., Jelinek, J., Piwocka, K., Sliwinski, T., Stoklosa, T., Ploski, R., Fischer, T., Sykes, S.M., Koschmieder, S., Bullinger, L., Valent, P., Wasik, M.A., Huang, J. and Skorski, T.
Blood 132 (1): 67-77. 5 July 2018

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.
Makarewich, C.A., Munir, A.Z., Schiattarella, G.G., Bezprozvannaya, S., Raguimova, O.N., Cho, E.E., Vidal, A.H., Robia, S.L., Bassel-Duby, R. and Olson, E.N.
eLife 7 : e38319. 9 October 2018

Exon skipping in a Dysf-missense mutant mouse model.
Malcher, J., Heidt, L., Goyenvalle, A., Escobar, H., Marg, A., Beley, C., Benchaouir, R., Bader, M., Spuler, S., García, L. and Schöwel, V.
Molecular Therapy - Nucleic Acids 13 : 198-207. 7 December 2018

Transient receptor potential vanilloid 4 channel deficiency aggravates tubular damage after acute renal ischaemia reperfusion.
Mannaa, M., Markó, L., Balogh, A., Vigolo, E., N'diaye, G., Kaßmann, M., Michalick, L., Weichelt, U., Schmidt-Ott, K.M., Liedtke, W.B., Huang, Y., Müller, D.N., Kuebler, W.M. and Gollasch, M.
Scientific Reports 8 (1): 4878. 20 March 2018

Challenges and guidelines toward 4D nucleome data and model standards.
Marti-Renom, M.A., Almouzni, G., Bickmore, W.A., Bystricky, K., Cavalli, G., Fraser, P., Gasser, S.M., Giorgetti, L., Heard, E., Nicodemi, M., Nollmann, M., Orozco, M., Pombo, A. and Torres-Padilla, M.E.
Nature Genetics 50 (10): 1352-1358. October 2018

Mutations in TOP3A cause a bloom syndrome-like disorder.
Martin, C.A., Sarlós, K., Logan, C.V., Thakur, R.S., Parry, D.A., Bizard, A.H., Leitch, A., Cleal, L., Ali, N.S., Al-Owain, M.A., Allen, W., Altmüller, J., Aza-Carmona, M., Barakat, B.A.Y., Barraza-García, J., Begtrup, A., Bogliolo, M., Cho, M.T., Cruz-Rojo, J., Dhahrabi, H.A.M., Elcioglu, N.H., Gorman, G.S., Jobling, R., Kesterton, I., Kishita, Y., Kohda, M., Le Quesne Stabej, P., Malallah, A.J., Nürnberg, P., Ohtake, A., Okazaki, Y., Pujol, R., Ramirez, M.J., Revah-Politi, A., Shimura, M., Stevens, P., Taylor, R.W., Turner, L., Williams, H., Wilson, C., Yigit, G., Zahavich, L., Alkuraya, F.S., Surralles, J., Iglesias, A., Murayama, K., Wollnik, B., Dattani, M., Heath, K.E., Hickson, I.D. and Jackson, A.P.
American Journal of Human Genetics 103 (2): 221-231. 2 August 2018

Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo.
Maschmeyer, P., Petkau, G., Siracusa, F., Zimmermann, J., Zügel, F., Kühl, A.A., Lehmann, K., Schimmelpfennig, S., Weber, M., Haftmann, C., Riedel, R., Bardua, M., Heinz, G.A., Tran, C.L., Hoyer, B.F., Hiepe, F., Herzog, S., Wittmann, J., Rajewsky, N., Melchers, F.G., Chang, H.D., Radbruch, A. and Mashreghi, M.F.
Journal of Autoimmunity 89 : 41-52. May 2018

How to make a tumour: cell type specific dissection of Ustilago maydis-induced tumour development in maize leaves.
Matei, A., Ernst, C., Günl, M., Thiele, B., Altmüller, J., Walbot, V., Usadel, B. and Doehlemann, G.
New Phytologist 217 (4): 1681-1695. March 2018

Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis.
Matthes, F., Hettich, M.M., Schilling, J., Flores-Dominguez, D., Blank, N., Wiglenda, T., Buntru, A., Wolf, H., Weber, S., Vorberg, I., Dagane, A., Dittmar, G., Wanker, E., Ehninger, D. and Krauss, S.
Cell Death Discovery 4 : 4. 29 January 2018

Reducing mutant huntingtin protein expression in living cells by a newly identified RNA CAG binder.
Matthes, F., Massari, S., Bochicchio, A., Schorpp, K., Schilling, J., Weber, S., Offermann, N., Desantis, J., Wanker, E.E., Carloni, P., Hadian, K., Tabarrini, O., Rossetti, G. and Krauss, S.
ACS Chemical Neuroscience 9 (6): 1399-1408. 20 June 2018

Rare coding variants in genes encoding GABA A receptors in genetic generalised epilepsies: an exome-based case-control study.
May, P., Girard, S., Harrer, M., Bobbili, D.R., Schubert, J., Wolking, S., Becker, F., Lachance-Touchette, P., Meloche, C., Gravel, M., Niturad, C.E., Knaus, J., De Kovel, C., Toliat, M., Polvi, A., Iacomino, M., Guerrero-López, R., Baulac, S., Marini, C., Thiele, H., Altmüller, J., Jabbari, K., Ruppert, A.K., Jurkowski, W., Lal, D., Rusconi, R., Cestèle, S., Terragni, B., Coombs, I.D., Reid, C.A., Striano, P., Caglayan, H., Siren, A., Everett, K., Møller, R.S., Hjalgrim, H., Muhle, H., Helbig, I., Kunz, W.S., Weber, Y.G., Weckhuysen, S., Jonghe, P.D., Sisodiya, S.M., Nabbout, R., Franceschetti, S., Coppola, A., Vari, M.S., Kasteleijn-Nolst Trenité, D., Baykan, B., Ozbek, U., Bebek, N., Klein, K.M., Rosenow, F., Nguyen, D.K., Dubeau, F., Carmant, L., Lortie, A., Desbiens, R., Clément, J.F., Cieuta-Walti, C., Sills, G.J., Auce, P., Francis, B., Johnson, M.R., Marson, A.G., Berghuis, B., Sander, J.W., Avbersek, A., McCormack, M., Cavalleri, G.L., Delanty, N., Depondt, C., Krenn, M., Zimprich, F., Peter, S., Nikanorova, M., Kraaij, R., van Rooij, J., Balling, R., Ikram, M.A., Uitterlinden, A.G., Avanzini, G., Schorge, S., Petrou, S., Mantegazza, M., Sander, T., LeGuern, E., Serratosa, J.M., Koeleman, B.P.C., Palotie, A., Lehesjoki, A.E., Nothnagel, M., Nürnberg, P., Maljevic, S., Zara, F., Cossette, P., Krause, R. and Lerche, H.
Lancet Neurology 17 (8): 699-708. August 2018

Vaccines and the association with relapses in patients with neuromyelitis optica spectrum disorder.
Mealy, M.A., Cook, L.J., Pache, F., Velez, D.L., Borisow, N., Becker, D., Jimenez Arango, J.A., Paul, F. and Levy, M.
Multiple Sclerosis and Related Disorders 23 : 78-82. July 2018

Aquaporin-4 serostatus does not predict response to immunotherapy in neuromyelitis optica spectrum disorders.
Mealy, M.A., Kim, S.H., Schmidt, F., López, R., Jimenez Arango, J.A., Paul, F., Wingerchuk, D.M., Greenberg, B.M., Kim, H.Jin. and Levy, M.
Multiple Sclerosis Journal 24 (13): 1737-1742. 1 November 2018

Brain region-specific expression of genes mapped within quantitative trait loci for behavioral responsiveness to acute stress in Fisher 344 and Wistar Kyoto male rats.
Meckes, J.K., Lim, P.H., Wert, S.L., Luo, W., Gacek, S.A., Platt, D., Jankord, R., Saar, K. and Redei, E.E.
PLoS ONE 13 (3): e0194293. 12 March 2018

User experience and clinical effectiveness with two wearable global positioning system devices in home dementia care.
Megges, H., Freiesleben, S.D., Rösch, C., Knoll, N., Wessel, L. and Peters, O.
Alzheimer's and Dementia: Translational Research and Clinical Interventions 4 : 636-644. 9 November 2018

Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations.
Meral, D., Provasi, D., Prada-Gracia, D., Möller, J., Marino, K., Lohse, M.J. and Filizola, M.
Scientific Reports 8 (1): 7705. 16 May 2018

Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity.
Merks, A.M., Swinarski, M., Meyer, A.M., Müller, N.V., Özcan, I., Donat, S., Burger, A., Gilbert, S., Mosimann, C., Abdelilah-Seyfried, S. and Panáková, D.
Nature Communications 9 (1): 2161. 4 June 2018

Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry.
Mertins, P., Tang, L.C., Krug, K., Clark, D.J., Gritsenko, M.A., Chen, L., Clauser, K.R., Clauss, T.R., Shah, P., Gillette, M.A., Petyuk, V.A., Thomas, S.N., Mani, D.R., Mundt, F., Moore, R.J., Hu, Y., Zhao, R., Schnaubelt, M., Keshishian, H., Monroe, M.E., Zhang, Z., Udeshi, N.D., Mani, D., Davies, S.R., Townsend, R.R., Chan, D.W., Smith, R.D., Zhang, H., Liu, T. and Carr, S.A.
Nature Protocols 13 (7): 1632-1661. July 2018

Nervous system regionalization entails axial allocation before neural differentiation.
Metzis, V., Steinhauser, S., Pakanavicius, E., Gouti, M., Stamataki, D., Ivanovitch, K., Watson, T., Rayon, T., Mousavy Gharavy, S.N., Lovell-Badge, R., Luscombe, N.M. and Briscoe, J.
Cell 175 (4): 1105-1118. 1 November 2018

Silencing the CSF-1 axis using nanoparticle encapsulated siRNA mitigates viral and autoimmune myocarditis.
Meyer, I.S., Goetzke, C.C., Kespohl, M., Sauter, M., Heuser, A., Eckstein, V., Vornlocher, H.P., Anderson, D.G., Haas, J., Meder, B., Katus, H.A., Klingel, K., Beling, A. and Leuschner, F.
Frontiers in Immunology 9 : 2303. 8 October 2018

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K., Kirchner, M., Uyar, B., Cheng, J.Y., Russo, G., Hernandez-Miranda, L.R., Szymborska, A., Zauber, H., Rudolph, I.M., Willnow, T.E., Akalin, A., Haucke, V., Gerhardt, H., Birchmeier, C., Kühn, R., Krauss, M., Diecke, S., Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

Oligodendrocytes in the mouse corpus callosum maintain axonal function by delivery of glucose.
Meyer, N., Richter, N., Fan, Z., Siemonsmeier, G., Pivneva, T., Jordan, P., Steinhäuser, C., Semtner, M., Nolte, C. and Kettenmann, H.
Cell Reports 22 (9): 2383-2394. 27 February 2018

The angiotensin II type 2 receptors protect renal tubule mitochondria in early stages of diabetes mellitus.
Micakovic, T., Papagiannarou, S., Clark, E., Kuzay, Y., Abramovic, K., Peters, J., Sticht, C., Volk, N., Fleming, T., Nawroth, P., Hammes, H.P., Alenina, N., Gröne, H.J. and Hoffmann, S.C.
Kidney International 94 (5): 937-950. November 2018

Convergence to equilibrium in energy-reaction–diffusion systems using vector-valued functional inequalities.
Mielke, A. and Mittnenzweig, M.
Journal of Nonlinear Science 28 (2): 765-806. April 2018

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N., Kolesnichenko, M., Beaudette, P., Popp, O., Uyar, B., Sun, W., Tufan, A.B., Perder, B., Akalin, A., Chen, W., Mertins, P., Dittmar, G., Hinz, M. and Scheidereit, C.
EMBO Journal 37 (24): e98658. 14 December 2018

Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M., Fan, D.N.Y., Belenki, D., Däbritz, J.H.M., Zhao, Z., Yu, Y., Dörr, J.R., Dimitrova, L., Lenze, D., Monteiro Barbosa, I.A., Mendoza-Parra, M.A., Kanashova, T., Metzner, M., Pardon, K., Reimann, M., Trumpp, A., Dörken, B., Zuber, J., Gronemeyer, H., Hummel, M., Dittmar, G., Lee, S. and Schmitt, C.A.
Nature 553 (7686): 96-100. 4 January 2018

Systematic detection of poly(A)(+) RNA-interacting proteins and their differential binding.
Milek, M. and Landthaler, M.
Methods in Molecular Biology 1649 : 405-417. 2018

Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Ming, Q., Roske, Y., Schuetz, A., Walentin, K., Ibraimi, I., Schmidt-Ott, K.M. and Heinemann, U.
Nucleic Acids Research 46 (4): 2082-2095. 28 February 2018

Small molecules co-targeting CKIα and the transcriptional kinases CDK7/9 control AML in preclinical models.
Minzel, W., Venkatachalam, A., Fink, A., Hung, E., Brachya, G., Burstain, I., Shaham, M., Rivlin, A., Omer, I., Zinger, A., Elias, S., Winter, E., Erdman, P.E., Sullivan, R.W., Fung, L., Mercurio, F., Li, D., Vacca, J., Kaushansky, N., Shlush, L., Oren, M., Levine, R., Pikarsky, E., Snir-Alkalay, I. and Ben-Neriah, Y.
Cell 175 (1): 171-185.e25. 20 September 2018

Classical cardiovascular risk markers in pregnancy and associations to uteroplacental acute atherosis.
Moe, K., Alnaes-Katjavivi, P., Storvold, G.L., Sugulle, M., Johnsen, G.M., Redman, C.W.G., Dechend, R. and Staff, A.C.S.
Hypertension 72 (3): 695-702. September 2018

The cell fate determinant Scribble is required for maintenance of hematopoietic stem cell function.
Mohr, J., Dash, B.P., Schnoeder, T.M., Wolleschak, D., Herzog, C., Tubio Santamaria, N., Weinert, S., Godavarthy, S., Zanetti, C., Naumann, M., Hartleben, B., Huber, T.B., Krause, D.S., Kähne, T., Bullinger, L. and Heidel, F.H.
Leukemia 32 (5): 1211-1221. May 2018

Leptomeningeal and intraparenchymal blood barrier disruption in a MOG-IgG-positive patient.
Mohseni, S.H., Skejoe, H.P.B., Wuerfel, J., Paul, F., Reindl, M., Jarius, S. and Asgari, N.
Case Reports in Neurological Medicine 2018 : 1365175. 9 December 2018

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.
Molnos, S., Wahl, S., Haid, M., Eekhoff, E.M.W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H.H., van Leeuwen, N., Simonis-Bik, A.M.C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B., Herder, C., Rathmann, W., Roden, M., Gieger, C., Kramer, M.H.H., van Heemst, D., Pedersen, H.K., Gudmundsdottir, V., Schulze, M.B., Pischon, T., de Geus, E.J.C., Boeing, H., Boomsma, D.I., Ziegler, A.G., Slagboom, P.E., Hummel, S., Beekman, M., Grallert, H., Brunak, S., McCarthy, M.I., Gupta, R., Pearson, E.R., Adamski, J. and 't Hart, L.M.
Diabetologia 61 (1): 117-129. January 2018

Burst-like transcription of mutant and wildtype MYH7-alleles as possible origin of cell-to-cell contractile imbalance in hypertrophic cardiomyopathy.
Montag, J., Kowalski, K., Makul, M., Ernstberger, P., Radocaj, A., Beck, J., Becker, E., Tripathi, S., Keyser, B., Mühlfeld, C., Wissel, K., Pich, A., van der Velden, J., Dos Remedios, C.G., Perrot, A., Francino, A., Navarro-López, F., Brenner, B. and Kraft, T.
Frontiers in Physiology 9 : 359. 9 April 2018

Helicobacter pylori depletes cholesterol in gastric glands to prevent interferon gamma signaling and escape the inflammatory response.
Morey, P., Pfannkuch, L., Pang, E., Boccellato, F., Sigal, M., Imai-Matsushima, A., Dyer, V., Koch, M., Mollenkopf, H.J., Schlaermann, P. and Meyer, T.F.
Gastroenterology 154 (5): 1391-1404. April 2018

Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats.
Morgan, H.L., Butler, E., Ritchie, S., Herse, F., Dechend, R., Beattie, E., McBride, M.W. and Graham, D.
Hypertension 72 (1): 208-218. July 2018

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning.
Morgani, S.M., Metzger, J.J., Nichols, J., Siggia, E.D. and Hadjantonakis, A.K.
eLife 7 : e32839. 7 February 2018

Voltage gating of mechanosensitive PIEZO channels.
Moroni, M., Servin-Vences, M.R., Fleischer, R., Sánchez-Carranza, O. and Lewin, G.R.
Nature Communications 9 (1): 1096. 15 March 2018

Testicular macrophages: guardians of fertility.
Mossadegh-Keller, Noushin and Sieweke, M.H.
Cellular Immunology 330 : 120-125. August 2018

Depletion of Nesprin-2 is associated with an embryonic lethal phenotype in mice.
Mroß, C., Marko, M., Munck, M., Glöckner, G., Motameny, S., Altmüller, J., Noegel, A.A., Eichinger, L., Peche, V.S. and Neumann, S.
Nucleus 9 (1): 503-515. 20 October 2018

Comparison of fast multi-slice and standard segmented techniques for detection of late gadolinium enhancement in ischemic and non-ischemic cardiomyopathy - a prospective clinical cardiovascular magnetic resonance trial.
Muehlberg, F., Arnhold, K., Fritschi, S., Funk, S., Prothmann, M., Kermer, J., Zange, L., von Knobelsdorff-Brenkenhoff, F. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 20 (1): 13. 19 February 2018

Native myocardial T1 time can predict development of subsequent anthracycline-induced cardiomyopathy.
Muehlberg, F., Funk, S., Zange, L., von Knobelsdorff-Brenkenhoff, F., Blaszczyk, E., Schulz, A., Ghani, S., Reichardt, A., Reichardt, P. and Schulz-Menger, J.
ESC Heart Failure 5 (4): 620-629. August 2018

Pharmacological fMRI: effects of subanesthetic ketamine on resting-state functional connectivity in the default mode network, salience network, dorsal attention network and executive control network.
Mueller, F., Musso, F., London, M., de Boer, P., Zacharias, N. and Winterer, G.
NeuroImage: Clinical 19 : 745-757. 1 June 2018

Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple-negative breast cancers.
Mundt, F., Rajput, S., Li, S., Ruggles, K.V., Mooradian, A.D., Mertins, P., Gillette, M.A., Krug, K., Guo, Z., Hoog, J., Erdmann-Gilmore, P., Primeau, T., Huang, S., Edwards, D.P., Wang, X., Wang, X., Kawaler, E., Mani, D.R., Clauser, K.R., Gao, F., Luo, J., Davies, S.R., Johnson, G.L., Huang, K.L., Yoon, C.J., Ding, L., Fenyö, D., Ellis, M.J., Townsend, R.R., Held, J.M., Carr, S.A. and Ma, C.X.
Cancer Research 78 (10): 2732-2746. May 2018

SSMART: Sequence-structure motif identification for RNA-binding proteins.
Munteanu, A., Mukherjee, N. and Ohler, U.
Bioinformatics 34 (23): 3990-3998. 1 December 2018

The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice.
Murthy, S.E., Loud, M.C., Daou, I., Marshall, K.L., Schwaller, F., Kühnemund, J., Francisco, A.G., Keenan, W.T., Dubin, A.E., Lewin, G.R. and Patapoutian, A.
Science Translational Medicine 10 (462): eaat9897. 10 October 2018

Metabolic, mental and immunological effects of normoxic and hypoxic training in multiple sclerosis patients: a pilot study.
Mähler, A., Balogh, A., Csizmadia, I., Klug, L., Kleinewietfeld, M., Steiniger, J., Šušnjar, U., Müller, D.N., Boschmann, M. and Paul, F.
Frontiers in Immunology 9 : 2819. November 2018

Pan-class I  PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.
Müller, A., Gillissen, B., Richter, A., Richter, A., Chumduri, C., Daniel, P.T. and Scholz, C.W.
Cell Death & Disease 9 (3): 384. 7 March 2018

Influence of estrogen on individual exercise motivation and bone protection in ovariectomized rats.
Müller, S.T., Keiler, A.M., Kräker, K., Zierau, O. and Bernhardt, R.
Laboratory Animals 52 (5): 479-489. October 2018

Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons.
Müller, T., Braud, S., Jüttner, R., Voigt, B.C., Paulick, K., Sheean, M.E., Klisch, C., Gueneykaya, D., Rathjen, F.G., Geiger, J.R.P., Poulet, J.F.A. and Birchmeier, C.
EMBO Journal 37 (17): e98858. 3 September 2018

Apelinergic system in the kidney: implications for diabetic kidney disease.
Müller, T., Kalea, A.Z., Marquez, A., Hsieh, I., Haque, S., Ye, M., Wysocki, J., Bader, M. and Batlle, D.
Physiological Reports 6 (23): e13939. December 2018

Ca(2+)-activated Cl(-) currents in the murine vomeronasal organ enhance neuronal spiking but are dispensable for male-male aggression.
Münch, J., Billig, G., Huebner, C.A., Leinders-Zufall, T., Zufall, F. and Jentsch, T.J.
Journal of Biological Chemistry 293 (26): 10392-10403. 29 June 2018

The RhoGAP Stard13 controls insulin secretion through F-actin remodeling.
Naumann, H., Rathjen, T., Poy, M.N. and Spagnoli, F.M.
Molecular Metabolism 8 : 96-105. February 2018

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development.
Neto, F., Klaus-Bergmann, A., Ong, Y.T., Alt, S., Vion, A.C., Szymborska, A., Carvalho, J.R., Hollfinger, I., Bartels-Klein, E., Franco, C.A., Potente, M. and Gerhardt, H.
eLife 7 : e31037. 5 February 2018

The patients' view: impact of the extent of resection, intraoperative imaging, and awake surgery on health-related quality of life in high-grade glioma patients-results of a multicenter cross-sectional study.
Nickel, K., Renovanz, M., König, J., Stöckelmaier, L., Hickmann, A.K., Nadji-Ohl, M., Engelke, J., Weimann, E., Freudenstein, D., Ganslandt, O., Bullinger, L., Wirtz, C.R. and Coburger, J.
Neurosurgical Review 41 (1): 207-219. January 2018

Dataset on the activation of Mueller cells through macrophages upon hypoxia in the retina.
Nuernberg, C., Kociok, N., Brockmann, C., Lischke, T., Crespo-Garcia, S., Reichhart, N., Wolf, S., Baumgrass, R., Eming, S.A., Beer-Hammer, S. and Joussen, A.M.
Data in Brief 16 : 489-500. February 2018

Myeloid cells contribute indirectly to VEGF expression upon hypoxia via activation of Müller cells.
Nuernberg, C., Kociok, N., Brockmann, C., Lischke, T., Crespo-Garcia, S., Reichhart, N., Wolf, S., Baumgrass, R., Eming, S.A., Beer-Hammer, S. and Joussen, A.M.
Experimental Eye Research 166 : 56-69. January 2018

Multicenter reliability of semiautomatic retinal layer segmentation using OCT.
Oberwahrenbrock, T., Traber, G.L., Lukas, S., Gabilondo, I., Nolan, R., Songster, C., Balk, L., Petzold, A., Paul, F., Villoslada, P., Brandt, A.U., Green, A.J. and Schippling, S.
Neurology Neuroimmunology & Neuroinflammation 5 (3): e449. 1 May 2018

Retinal ganglion cell loss in neuromyelitis optica: a longitudinal study.
Oertel, F.C., Havla, J., Roca-Fernández, A., Lizak, N., Zimmermann, H., Motamedi, S., Borisow, N., White, O.B., Bellmann-Strobl, J., Albrecht, P., Ruprecht, K., Jarius, S., Palace, J., Leite, M.I., Kuempfel, T., Paul, F. and Brandt, A.U.
Journal of Neurology Neurosurgery and Psychiatry 89 (12): 1259-1265. December 2018

The UNC-83/UNC-84 LINC members are required for body wall muscle nuclei positioning in C. elegans.
Ofenbauer, A. and Tursun, B.
Matters Select 31 May 2018

Validation of simulations in multiphase flow metrology by comparison with experimental video observations.
Olbrich, M., Schmeyer, E., Riazy, L., Oberleithner, K., Bär, M. and Schmelter, S.
Journal of Physics: Conference Series 1065 (9): 092015. 13 November 2018

Finding RNA structure in the unstructured RBPome.
Orenstein, Y., Ohler, U. and Berger, B.
BMC Genomics 19 (1): 154. 20 February 2018

Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations.
Otten, C., Knox, J., Boulday, G., Eymery, M., Haniszewski, M., Neuenschwander, M., Radetzki, S., Vogt, I., Hähn, K., De Luca, C., Cardoso, C., Hamad, S., Igual Gil, C., Roy, P., Albiges‐Rizo, C., Faurobert, E., von Kries, J.P., Campillos, M., Tournier‐Lasserve, E., Derry, W.B. and Abdelilah-Seyfried, S.
EMBO Molecular Medicine 10 (10): e9155. 1 October 2018

Hypoxia-reoxygenation enhances murine afferent arteriolar vasoconstriction by angiotensin II.
Pahlitzsch, T.M., Liu, Z.Z., Al-Masri, A., Braun, D., Dietze, S., Persson, P.B., Schunck, W.H., Blum, M., Kupsch, E., Ludwig, M. and Patzak, A.
American Journal of Physiology Renal Physiology 314 (3): F430-F438. March 2018

Recovery of gut microbiota of healthy adults following antibiotic exposure.
Palleja, A., Mikkelsen, K.H., Forslund, S.K., Kashani, A., Allin, K.H., Nielsen, T., Hansen, T.H., Liang, S., Feng, Q., Zhang, C., Pyl, P.T., Coelho, L.P., Yang, H., Wang, J., Typas, A., Nielsen, M.F., Nielsen, H.B., Bork, P., Wang, J., Vilsbøll, T., Hansen, T., Knop, F.K., Arumugam, M. and Pedersen, O.
Nature Microbiology 3 : 1255-1265. November 2018

De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females.
Palmer, E.E., Stuhlmann, T., Weinert, S., Haan, E., Van Esch, H., Holvoet, M., Boyle, J., Leffler, M., Raynaud, M., Moraine, C., van Bokhoven, H., Kleefstra, T., Kahrizi, K., Najmabadi, H., Ropers, H.H., Delgado, M.R., Sirsi, D., Golla, S., Sommer, A., Pietryga, M.P., Chung, W.K., Wynn, J., Rohena, L., Bernardo, E., Hamlin, D., Faux, B.M., Grange, D.K., Manwaring, L., Tolmie, J., Joss, S., Cobben, J.M., Duijkers, F.A.M., Goehringer, J.M., Challman, T.D., Hennig, F., Fischer, U., Grimme, A., Suckow, V., Musante, L., Nicholl, J., Shaw, M., Lodh, S.P., Niu, Z., Rosenfeld, J.A., Stankiewicz, P., Jentsch, T.J., Gecz, J., Field, M. and Kalscheuer, V.M.
Molecular Psychiatry 23 (2): 222-230. February 2018

Athymic mice reveal a requirement for T-cell-microglia interactions in establishing a microenvironment supportive of Nf1 low-grade glioma growth.
Pan, Y., Xiong, M., Chen, R., Ma, Y., Corman, C., Maricos, M., Kindler, U., Semtner, M., Chen, Y.H., Dahiya, S. and Gutmann, D.H.
Genes & Development 32 (7-8): 491-496. 9 April 2018

Importin α5 regulates anxiety through MeCP2 and sphingosine kinase 1.
Panayotis, N., Sheinin, A., Dagan, S.Y., Tsoory, M.M., Rother, F., Vadhvani, M., Meshcheriakova, A., Koley, S., Marvaldi, L., Song, D.A., Reuveny, E., Eickholt, B.J., Hartmann, E., Bader, M., Michaelevski, I. and Fainzilber, M.
Cell Reports 25 (11): 3169-3179. 11 December 2018

Targeted resequencing reveals genomic signatures of barley domestication.
Pankin, A., Altmüller, J., Becker, C. and von Korff, M.
New Phytologist 218 (3): 1247-1259. May 2018

Specific combinations of biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndrome.
Paolacci, S., Li, Y., Agolini, E., Bellacchio, E., Arboleda-Bustos, C.E., Carrero, D., Bertola, D., Al-Gazali, L., Alders, M., Altmüller, J., Arboleda, G., Beleggia, F., Bruselles, A., Ciolfi, A., Gillessen-Kaesbach, G., Krieg, T., Mohammed, S., Müller, C., Novelli, A., Ortega, J., Sandoval, A., Velasco, G., Yigit, G., Arboleda, H., Lopez-Otin, C., Wollnik, B., Tartaglia, M. and Hennekam, R.C.
Journal of Medical Genetics 55 (12): 837-846. December 2018

Optische Kohärenztomografie bei Erkrankungen des zentralen Nervensystems [Optical coherence tomography in disorders of the central nervous system].
Papadopoulou, A., Oertel, F.C., Zimmermann, H., Zeitz, O., Brandt, A.U. and Paul, F.
Klinische Monatsblaetter fuer Augenheilkunde 235 (11): 1242-1258. 20 November 2018

Quantifying compartment-associated variations of protein abundance in proteomics data.
Parca, L., Beck, M., Bork, P. and Ori, A.
Molecular Systems Biology 14 (7): e8131. 2 July 2018

Adding dasatinib to intensive treatment in core-binding factor acute myeloid leukemia-results of the AMLSG 11-08 trial.
Paschka, P., Schlenk, R.F., Weber, D., Benner, A., Bullinger, L., Heuser, M., Gaidzik, V.I., Thol, F., Agrawal, M., Teleanu, V., Lübbert, M., Fiedler, W., Radsak, M., Krauter, J., Horst, H.A., Greil, R., Mayer, K., Kündgen, A., Martens, U., Heil, G., Salih, H.R., Hertenstein, B., Schwänen, C., Wulf, G., Lange, E., Pfreundschuh, M., Ringhoffer, M., Girschikofsky, M., Heinicke, T., Kraemer, D., Göhring, G., Ganser, A., Döhner, K. and Döhner, H.
Leukemia 32 (7): 1621-1630. July 2018

The antibiotic-free pFAR4 vector paired with the sleeping beauty transposon sSystem mediates efficient transgene delivery in human cells.
Pastor, M., Johnen, S., Harmening, N., Quiviger, M., Pailloux, J., Kropp, M., Walter, P., Ivics, Z., Izsvák, Z., Thumann, G., Scherman, D. and Marie, C.
Molecular Therapy - Nucleic Acids 11 : 57-67. 1 June 2018

The genetic ancestry of modern Indus Valley populations from Northwest India.
Pathak, A.K., Kadian, A., Kushniarevich, A., Montinaro, F., Mondal, M., Ongaro, L., Singh, M., Kumar, P., Rai, N., Parik, J., Metspalu, E., Rootsi, S., Pagani, L., Kivisild, T., Metspalu, M., Chaubey, G. and Villems, R.
American Journal of Human Genetics 103 (6): 918-929. 6 December 2018

Multiband diffusion-weighted MRI of the eye and orbit free of geometric distortions using a RARE-EPI hybrid.
Paul, K., Huelnhagen, T., Oberacker, E., Wenz, D., Kuehne, A., Waiczies, H., Schmitter, S., Stachs, O. and Niendorf, T.
NMR in Biomedicine 31 (3): e3872. March 2018

CSF-progranulin and neurofilament light chain levels in patients with radiologically isolated syndrome - sign of inflammation.
Pawlitzki, M., Sweeney-Reed, C.M., Bittner, D., Lux, A., Vielhaber, S., Schreiber, S., Paul, F. and Neumann, J.
Frontiers in Neurology 9 : 1075. December 2018

A computational framework to integrate high-throughput '-omics' datasets for the identification of potential mechanistic links.
Pedersen, H.K., Forslund, S.K., Gudmundsdottir, V., Petersen, A.Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, T., Bork, P., Ehrlich, S.D., Brunak, S., Oresic, M., Pedersen, O. and Nielsen, H.B.
Nature Protocols 13 (12): 2781-2800. December 2018

Isolation of native plasma membrane H(+)-ATPase (Pma1p) in both the active and basal activation states.
Pedersen, J.T., Kanashova, T., Dittmar, G. and Palmgren, M.
FEBS Open Bio 8 (5): 774-783. May 2018

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery.
Peeva, V., Blei, D., Trombly, G., Corsi, S., Szukszto, M.J., Rebelo-Guiomar, P., Gammage, P.A., Kudin, A.P., Becker, C., Altmüller, J., Minczuk, M., Zsurka, G. and Kunz, W.S.
Nature Communications 9 (1): 1727. 30 April 2018

Identification of protein phosphatase involvement in the AT(2)-receptor induced activation of endothelial nitric oxide synthase.
Peluso, A.A., Bertelsen, J.B., Andersen, K., Mortensen, T.P., Hansen, P.B., Sumners, C., Bader, M., Santos, R.A. and Steckelings, U.M.
Clinical Science 132 (7): 777-790. 6 April 2018

Superficial white matter damage in anti-NMDA receptor encephalitis.
Phillips, O. R., Joshi, S.H., Narr, K.L., Shattuck, D.W., Singh, M., Di Paola, M., Ploner, C.J., Prüss, H., Paul, F. and Finke, C.
Journal of Neurology Neurosurgery and Psychiatry 89 (5): 518-525. May 2018

A map of protein-metabolite interactions reveals principles of chemical communication.
Piazza, I., Kochanowski, K., Cappelletti, V., Fuhrer, T., Noor, E., Sauer, U. and Picotti, P.
Cell 172 (1-2): 358-372. 11 January 2018

Joint data analysis in nutritional epidemiology: identification of observational studies and minimal requirements.
Pinart, M., Nimptsch, K., Bouwman, J., Dragsted, L.O., Yang, C., De Cock, N., Lachat, C., Perozzi, G., Canali, R., Lombardo, R., D'Archivio, M., Guillaume, M., Donneau, A.F., Jeran, S., Linseisen, J., Kleiser, C., Nöthlings, U., Barbaresko, J., Boeing, H., Stelmach-Mardas, M., Heuer, T., Laird, E., Walton, J., Gasparini, P., Robino, A., Castaño, L., Rojo-Martínez, G., Merino, J., Masana, L., Standl, M., Schulz, H., Biagi, E., Nurk, E., Matthys, C., Gobbetti, M., de Angelis, M., Windler, E., Zyriax, B.C., Tafforeau, J. and Pischon, T.
Journal of Nutrition 148 (2): 285-297. 1 February 2018

How effective is tacrolimus in the imiquimod-induced mouse model of psoriasis?
Pischon, H., Radbruch, M., Ostrowski, A., Schumacher, F., Hönzke, S., Kleuser, B., Hedtrich, S., Fluhr, J.W., Gruber, A.D. and Mundhenk, L.
The Journal of investigative dermatology 138 (2): 455-458. February 2018

Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics.
Plass, M., Solana, J., Wolf, F.A., Ayoub, S., Misios, A., Glažar, P., Obermayer, B., Theis, F.J., Kocks, C. and Rajewsky, N.
Science 360 (6391): eaaq1723. 25 May 2018

Evolutionary plasticity in the innate immune function of Akirin.
Polanowska, J., Chen, J.X., Soulé, J., Omi, S., Belougne, J., Taffoni, C., Pujol, N., Selbach, M., Zugasti, O. and Ewbank, J.J.
PLoS Genetics 14 (7): e1007494. 23 July 2018

High and long-term von Willebrand factor expression after Sleeping Beauty transposon-mediated gene therapy in a mouse model of severe von Willebrand disease.
Portier, I., Vanhoorelbeke, K., Verhenne, S., Pareyn, I., Vandeputte, N., Deckmyn, H., Goldenberg, D.S., Samal, H.B., Singh, M., Ivics, Z., Izsvák, Z. and De Meyer, S.F.
Journal of Thrombosis and Haemostasis 16 (3): 592-604. March 2018

Activation of Smoothened in the Hedgehog pathway unexpectedly increases Gα(s)-dependent cAMP levels in Drosophila.
Praktiknjo, S.D., Saad, F., Maier, D., Ip, P. and Hipfner, D.R.
Journal of Biological Chemistry 293 (35): 13496-13508. August 2018

De novo mutations implicate novel genes in systemic lupus erythematosus.
Pullabhatla, V., Roberts, A.L., Lewis, M.J., Mauro, D., Morris, D.L., Odhams, C.A., Tombleson, P., Liljedahl, U., Vyse, S., Simpson, M.A., Sauer, S., de Rinaldis, E., Syvänen, A.C. and Vyse, T.J.
Human Molecular Genetics 27 (3): 421-429. 1 February 2018

G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
Pusapati, G.V., Kong, J.H., Patel, B.B., Gouti, M., Sagner, A., Sircar, R., Luchetti, G., Ingham, P.W., Briscoe, J. and Rohatgi, R.
Science Signaling 11 (516): eaao5749. 6 February 2018

Ectopic transplastomic expression of a synthetic MatK gene leads to cotyledon-specific leaf variegation.
Qu, Y., Legen, J., Arndt, J., Henkel, S., Hoppe, G., Thieme, C., Ranzini, G., Muino, J.M., Weihe, A., Ohler, U., Weber, G., Ostersetzer, O. and Schmitz-Linneweber, C.
Frontiers in Plant Science 9 : 1453. October 2018

Increased fear learning, spatial learning as well as neophobia in Rgs2(-/-) mice.
Raab, A., Popp, S., Lesch, K.P., Lohse, M.J., Fischer, M., Deckert, J. and Hommers, L.
Genes Brain and Behavior 17 (4): e12420. April 2018

Kinase-controlled phase transition of membraneless organelles in mitosis.
Rai, A.K., Chen, J.X., Selbach, M. and Pelkmans, L.
Nature 559 (7713): 211-216. July 2018

miR-9-5p in nephrectomy specimens is a potential predictor of primary resistance to first-line treatment with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma.
Ralla, B., Busch, J., Flörcken, A., Westermann, J., Zhao, Z., Kilic, E., Weickmann, S., Jung, M., Fendler, A. and Jung, K.
Cancers 10 (9): 321. 10 September 2018

MRI markers and functional performance in patients with CIS and MS: a cross-sectional study.
Rasche, L., Scheel, M., Otte, K., Althoff, P., van Vuuren, A.B., Gieß, R.M., Kuchling, J., Bellmann-Strobl, J., Ruprecht, K., Paul, F., Brandt, A.U. and Schmitz-Hübsch, T.
Frontiers in Neurology 9 : 718. August 2018

Parasitic nematodes exert antimicrobial activity and benefit from microbiota-driven support for host immune regulation.
Rausch, S., Midha, A., Kuhring, M., Affinass, N., Radonic, A., Kühl, A.A., Bleich, A., Renard, B.Y. and Hartmann, S.
Frontiers in Immunology 9 : 2282. October 2018

Somatosensory BOLD fMRI reveals close link between salient blood pressure changes and the murine neuromatrix.
Reimann, H.M., Todiras, M., Hodge, Russ, Huelnhagen, T., Millward, J.M., Turner, R., Seeliger, E., Bader, M., Pohlmann, A. and Niendorf, T.
NeuroImage 172 : 562-574. 15 May 2018

Postnatal DNA demethylation and its role in tissue maturation.
Reizel, Y., Sabag, O., Skversky, Y., Spiro, A., Steinberg, B., Bernstein, D., Wang, A., Kieckhaefer, J., Li, C., Pikarsky, E., Levin-Klein, R., Goren, A., Rajewsky, K., Kaestner, K.H. and Cedar, H.
Nature Communications 9 (1): 2040. 23 May 2018

New insights into the cellular temporal response to proteostatic stress.
Rendleman, J., Cheng, Z., Maity, S., Kastelic, N., Munschauer, M., Allgoewer, K., Teo, G., Zhang, Y.B.M., Lei, A., Parker, B., Landthaler, M., Freeberg, L., Kuersten, S., Choi, H. and Vogel, C.
eLife 7 : e39054. 12 October 2018

RNA helicase DDX1 converts RNA G-quadruplex structures into R-loops to promote IgH class switch recombination.
Ribeiro de Almeida, C., Dhir, S., Dhir, A., Moghaddam, A.E., Sattentau, Q., Meinhart, A. and Proudfoot, N.J.
Molecular Cell 70 (4): 650-662. 17 May 2018

aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability.
Riddell, M., Nakayama, A., Hikita, T., Mirzapourshafiyi, F., Kawamura, T., Pasha, A., Li, M., Masuzawa, M., Looso, M., Steinbacher, T., Ebnet, K., Potente, M., Hirose, T., Ohno, S., Fleming, I., Gattenlöhner, S., Aung, P.P., Phung, T., Yamasaki, O., Yanagi, T., Umemura, H. and Nakayama, M.
Nature Communications 9 (1): 5357. 17 December 2018

Auto-antibodies against the angiotensin II type I receptor in women with uteroplacental acute atherosis and preeclampsia at delivery and several years postpartum.
Rieber-Mohn, A.B., Sugulle, M., Wallukat, G., Alnæs-Katjavivi, P., Leite Størvold, G., Bolstad, N., Redman, C.W., Dechend, R. and Staff, A.C.
Journal of Reproductive Immunology 128 : 23-29. August 2018

Human and equine endothelial cells in a live cell imaging scratch assay in vitro.
Rieger, J., Hopperdietzel, C., Kaessmeyer, S., Slosarek, I., Diecke, S., Richardson, K. and Plendl, J.
Clinical Hemorheology and Microcirculation 70 (4): 495-509. 2018

Confocal endomicroscopy in diagnosis of intestinal chronic graft-versus-host disease.
Rieger, K., Günther, U., Erben, U., Kühl, A., Loddenkemper, C., Pezzutto, A., Siegmund, B. and Bojarski, C.
Hematological Oncology 36 (1): 291-298. February 2018

Molecular basis for the sensitivity of TRP channels to polyunsaturated fatty acids.
Riehle, M., Tsvetkov, D., Gohlke, B.O., Preissner, R., Harteneck, C., Gollasch, M. and Nürnberg, B.
Naunyn-Schmiedeberg's Archives of Pharmacology 391 (8): 833-846. August 2018

Bi-allelic mutations in LSS, encoding lanosterol synthase, cause autosomal-recessive hypotrichosis simplex.
Romano, M.T., Tafazzoli, A., Mattern, M., Sivalingam, S., Wolf, S., Rupp, A., Thiele, H., Altmüller, J., Nürnberg, P., Ellwanger, J., Gambon, R., Baumer, Al., Kohlschmidt, N., Metze, D., Holdenrieder, S., Paus, R., Lütjohann, D., Frank, J., Geyer, M., Bertolini, M., Kokordelis, P. and Betz, R.C.
American Journal of Human Genetics 103 (5): 777-785. 1 November 2018

netSmooth: network-smoothing based imputation for single cell RNA-seq.
Ronen, J. and Akalin, A.
F1000Research 7 : 8. 10 July 2018

Epigenetics and epigenomics: implications for diabetes and obesity.
Rosen, E.D., Kaestner, K.H., Natarajan, R., Patti, M.E., Sallari, R., Sander, M. and Susztak, K.
Diabetes 67 (10): 1923-1931. 1 October 2018

Electroconductive biohybrid hydrogel for enhanced maturation and beating properties of engineered cardiac tissues.
Roshanbinfar, K., Vogt, L., Greber, B., Diecke, S., Boccaccini, A.R., Scheibel, T. and Engel, F.B.
Advanced Functional Materials 28 (42): 1803951. October 2018

Shp-2 is dispensable for establishing T cell exhaustion and for PD-1 signaling in vivo.
Rota, G., Niogret, C., Dang, A.T., Barros, C.R., Fonta, N.P., Alfei, F., Morgado, L., Zehn, D., Birchmeier, W., Vivier, E. and Guarda, G.
Cell Reports 23 (1): 39-49. 3 April 2018

Combined human genome-wide RNAi and metabolite analyses identify IMPDH as a host-directed target against Chlamydia infection.
Rother, M., Gonzalez, E., Teixeira da Costa, A.R., Wask, L., Gravenstein, I., Pardo, M., Pietzke, M., Gurumurthy, R.K., Angermann, J., Laudeley, R., Glage, S., Meyer, M., Chumduri, C., Kempa, S., Dinkel, K., Unger, A., Klebl, B., Klos, A. and Meyer, T.F.
Cell Host & Microbe 23 (5): 661-671. 9 May 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
Rozman, J., Rathkolb, B., Oestereicher, M.A., Schütt, C., Ravindranath, A.C., Leuchtenberger, S., Sharma, S., Kistler, M., Willershäuser, M., Brommage, R., Meehan, T.F., Mason, J., Haselimashhadi, H., Hough, T., Mallon, A.M., Wells, S., Santos, L., Lelliott, C.J., White, J.K., Sorg, T., Champy, M.F., Bower, L.R., Reynolds, C. L., Flenniken, A.M., Murray, St.A., Nutter, L.M.J., Svenson, K.L., West, D., Tocchini-Valentini, G.P., Beaudet, A.L., Bosch, F., Braun, R.B., Dobbie, M.S., Gao, X., Herault, Y., Moshiri, A., Moore, B.A., Kent Lloyd, K.C., McKerlie, C., Masuya, H., Tanaka, N., Flicek, P., Parkinson, H.E., Sedlacek, R., Seong, J.K., Wang, C.K.L., Moore, M., Brown, S.D., Tschöp, M.H., Wurst, W., Klingenspor, M., Wolf, E., Beckers, J., Machicao, F., Peter, A., Staiger, H., Häring, H.U., Grallert, H., Campillos, M., Maier, H., Fuchs, H., Gailus-Durner, V., Werner, T. and Hrabe de Angelis, M.
Nature Communications 9 (1): 288. 18 January 2018

Transposase-DNA complex structures reveal mechanisms for conjugative transposition of antibiotic resistance.
Rubio-Cosials, A., Schulz, E.C., Lambertsen, L., Smyshlyaev, G., Rojas-Cordova, C., Forslund, K., Karaca, E., Bebel, A., Bork, P. and Barabas, O.
Cell 173 (1): 208-220. 22 March 2018

RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia.
Rudat, S., Pfaus, A., Cheng, Y.Y., Holtmann, J., Ellegast, J.M., Bühler, C., Marcantonio, D.D., Martinez, E., Göllner, S., Wickenhauser, C., Müller-Tidow, C., Lutz, C., Bullinger, L., Milsom, M.D., Sykes, S.M., Fröhling, S. and Scholl, C.
Leukemia 32 (10): 2189-2202. October 2018

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Ruess, D.A., Heynen, G.J., Ciecielski, K.J., Ai, J., Berninger, A., Kabacaoglu, D., Görgülü, K., Dantes, Z., Wörmann, S.M., Diakopoulos, K.N., Karpathaki, A.F., Kowalska, M., Kaya-Aksoy, E., Song, L., Zeeuw van der Laan, E.A., López-Alberca, M.P., Nazaré, M., Reichert, M., Saur, D., Erkan, M.M., Hopt, U.T., Sainz, B., Birchmeier, W., Schmid, R.M., Lesina, M. and Algül, H.
Nature Medicine 24 (7): 954-960. July 2018

Chromosomal instability during neurogenesis in Huntington's disease.
Ruzo, A., Croft, G.F., Metzger, J.J., Galgoczi, S., Gerber, L.J., Pellegrini, C., Wang, H., Fenner, M., Tse, S., Marks, A., Nchako, C. and Brivanlou, A.H.
Development 145 (2) January 2018

Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes.
Rödiger, M., Werno, M.W., Wilhelmi, I., Baumeier, C., Hesse, D., Wettschureck, N., Offermanns, S., Song, K., Krauß, M. and Schürmann, A.
Molecular Metabolism 8 : 167-179. February 2018

Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.
Salatzki, J., Foryst-Ludwig, A., Bentele, K., Blumrich, A., Smeir, E., Ban, Z., Brix, S., Grune, J., Beyhoff, N., Klopfleisch, R., Dunst, S., Surma, M.A., Klose, C., Rothe, M., Heinzel, F.R., Krannich, A., Kershaw, E.E., Beule, D., Schulze, P.C., Marx, N. and Kintscher, U.
PLoS Genetics 14 (1): e1007171. 10 January 2018

Double layered stents for carotid angioplasty: a meta-analysis of available clinical data.
Sannino, A., Giugliano, G., Toscano, E., Schiattarella, G.G., Franzone, A., Tesorio, T., Trimarco, B., Esposito, G. and Stabile, E.
Catheterization and Cardiovascular Interventions 91 (4): 751-757. 1 March 2018

Comparison of baseline characteristics and outcomes in men versus women with aortic stenosis undergoing transcatheter aortic valve implantation.
Sannino, A., Szerlip, M., Harrington, K., Schiattarella, G.G. and Grayburn, P.A.
American Journal of Cardiology 121 (7): 844-849. 1 April 2018

Role of 3-acetyl-11-keto-beta-boswellic acid in counteracting LPS-induced neuroinflammation via modulation of miRNA-155.
Sayed, A.S., Gomaa, I.E.O., Bader, M. and El Sayed, N.S.E.D.
Molecular Neurobiology 55 (7): 5798-5808. July 2018

Loss of Akap1 exacerbates pressure overload-induced cardiac hypertrophy and heart failure.
Schiattarella, G.G., Boccella, N., Paolillo, R., Cattaneo, F., Trimarco, V., Franzone, A., D'Apice, S., Giugliano, G., Rinaldi, L., Borzacchiello, D., Gentile, A., Lombardi, A., Feliciello, A., Esposito, G. and Perrino, C.
Frontiers in Physiology 9 : 558. 28 May 2018

Rac1 modulates endothelial function and platelet aggregation in diabetes mellitus.
Schiattarella, G.G., Carrizzo, A., Ilardi, F., Damato, A., Ambrosio, M., Madonna, M., Trimarco, V., Marino, M., De Angelis, E., Settembrini, S., Perrino, C., Trimarco, B., Esposito, G. and Vecchione, C.
Journal of the American Heart Association 7 (8): e007322. 17 April 2018

Akap1 regulates vascular function and endothelial cells behavior.
Schiattarella, G.G., Cattaneo, F., Carrizzo, A., Paolillo, R., Boccella, N., Ambrosio, M., Pironti, G., Damato, A., Franzone, A., Russo, G., Magliulo, F., Pirozzi, M., Storto, M., Madonna, M., Gargiulo, G., Trimarco, V., Rinaldi, L., De Lucia, M., Garbi, C., Feliciello, A., Esposito, G., Vecchione, C. and Perrino, C.
Hypertension 71 (3): 507-517. March 2018

Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.
Schiffner, T., Pallesen, J., Russell, R.A., Dodd, J., de Val, N., LaBranche, C.C., Montefiori, D., Tomaras, G.D., Shen, X., Harris, S.L., Moghaddam, A.E., Kalyuzhniy, O., Sanders, R.W., McCoy, L.E., Moore, J.P., Ward, A.B. and Sattentau, Q.J.
PLoS Pathogens 14 (5): e1006986. 10 May 2018

A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics.
Schihada, H., Vandenabeele, S., Zabel, U., Frank, M., Lohse, M.J. and Maiellaro, I.
Communications Biology 1 : 105. 7 August 2018

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.
Schleussner, N., Merkel, O., Costanza, M., Liang, H.C., Hummel, F., Romagnani, C., Durek, P., Anagnostopoulos, I., Hummel, M., Jöhrens, K., Niedobitek, A., Griffin, P.R., Piva, R., Sczakiel, H.L., Woessmann, W., Damm-Welk, C., Hinze, C., Stoiber, D., Gillissen, B., Turner, S.D., Kaergel, E., von Hoff, L., Grau, M., Lenz, G., Dörken, B., Scheidereit, C., Kenner, L., Janz, M. and Mathas, S.
Leukemia 32 (9): 1994-2007. September 2018

Germline de novo mutations in ATP1A1 cause renal hypomagnesemia, refractory seizures, and intellectual disability.
Schlingmann, K.P., Bandulik, S., Mammen, C., Tarailo-Graovac, M., Holm, R., Baumann, M., König, J., Lee, J.J.Y., Drögemöller, B., Imminger, K., Beck, B.B., Altmüller, J., Thiele, H., Waldegger, S., Van't Hoff, W., Kleta, R., Warth, R., van Karnebeek, C.D.M., Vilsen, B., Bockenhauer, D. and Konrad, M.
American Journal of Human Genetics 103 (5): 808-816. 1 November 2018

The unexpected role of calcium-activated potassium channels: limitation of NO-induced arterial relaxation.
Schmid, J., Müller, B., Heppeler, D., Gaynullina, D., Kassmann, M., Gagov, H., Mladenov, M., Gollasch, M. and Schubert, R.
Journal of the American Heart Association 7 (7): e007808. 24 March 2018

The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea.
Schmidt, D., Reuter, H., Hüttner, K., Ruhe, L., Rabert, F., Seebeck, F., Irimia, M., Solana, J. and Bartscherer, K.
PLoS Genetics 14 (12): e1007828. 17 December 2018

Objective assessment of a relative afferent pupillary defect by B-mode ultrasound.
Schmidt, F.A., Connolly, F., Maas, M.B., Grittner, U., Harms, L., Brandt, A., Paul, F., Schreiber, S. and Ruprecht, K.
PLoS ONE 13 (8): e0202774. 27 August 2018

Regulation of the natriuretic peptide receptor 2 (Npr2) by phosphorylation of juxtamembrane serine and threonine residues is essential for bifurcation of sensory axons.
Schmidt, H., Dickey, D.M., Dumoulin, A., Octave, M., Robinson, J.W., Kühn, R., Feil, R., Potter, L.R. and Rathjen, F.G.
Journal of Neuroscience 38 (45): 9768-9780. 7 November 2018

ERAP1-dependent antigen cross-presentation determines efficacy of adoptive T cell therapy in mice.
Schmidt, K., Keller, C., Kühl, A.A., Textor, A., Seifert, U., Blankenstein, T., Willimsky, G. and Kloetzel, P.M.
Cancer Research 78 (12): 3243-3254. June 2018

Micro-ribonucleic acid-155 is a direct target of Meis1, but not a driver in acute myeloid leukemia.
Schneider, E., Staffas, A., Röhner, L., Malmberg, E.D., Ashouri, A., Krowiorz, K., Pochert, N., Miller, C., Wei, S.Y., Arabanian, L., Buske, C., Döhner, H., Bullinger, L., Fogelstrand, L., Heuser, M., Döhner, K., Xiang, P., Ruschmann, J., Petriv, O.I., Heravi-Moussavi, A., Hansen, C.L., Hirst, M., Humphries, R.K., Rouhi, A., Palmqvist, L. and Kuchenbauer, F.
Haematologica 103 (2): 246-255. February 2018

A general one-pot synthesis of 2H-indazoles using an organophosphorus-silane system.
Schoene, J., Bel Abed, H., Schmieder, P., Christmann, M. and Nazaré, M.
Chemistry - A European Journal 24 (36): 9090-9100. 26 June 2018

CLCN2 chloride channel mutations in familial hyperaldosteronism type II.
Scholl, U.I., Stölting, G., Schewe, J., Thiel, A., Tan, H., Nelson-Williams, C., Vichot, A.A., Jin, S.C., Loring, E., Untiet, V., Yoo, T., Choi, J., Xu, S., Wu, A., Kirchner, M., Mertins, P., Rump, L.C., Onder, A.M., Gamble, C., McKenney, D., Lash, R.W., Jones, D.P., Chune, G., Gagliardi, P., Choi, M., Gordon, R., Stowasser, M., Fahlke, C. and Lifton, R.P.
Nature Genetics 50 (3): 349-354. March 2018

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
Schrade, K., Tröger, J., Eldahshan, A., Zühlke, K., Abdul Azeez, K.R., Elkins, J.M., Neuenschwander, M., Oder, A., Elkewedi, M.M.H., Jaksch, S., Andrae, K., Li, J., Fernandes, J., Müller, P.M., Grunwald, S., Marino, S.F., Vukićević, T., Eichhorst, J., Wiesner, B., Weber, M., Kapiloff, M., Rocks, O., Daumke, O., Wieland, T., Knapp, S., von Kries, J.P. and Klussmann, E.
PLoS ONE 13 (1): e0191423. 26 January 2018

Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.
Schrader, A., Crispatzu, G., Oberbeck, S., Mayer, P., Pützer, S., von Jan, J., Vasyutina, E., Warner, K., Weit, N., Pflug, N., Braun, T., Andersson, E.I., Yadav, B., Riabinska, A., Maurer, B., Ventura Ferreira, M.S., Beier, F., Altmüller, J., Lanasa, M., Herling, C.D., Haferlach, T., Stilgenbauer, S., Hopfinger, G., Peifer, M., Brümmendorf, T.H., Nürnberg, P., Elenitoba-Johnson, K.S.J., Zha, S., Hallek, M., Moriggl, R., Reinhardt, H.C., Stern, M.H., Mustjoki, S., Newrzela, S., Frommolt, P. and Herling, M.
Nature Communications 9 (1): 697. 15 February 2018

Perturbation-response genes reveal signaling footprints in cancer gene expression.
Schubert, M., Klinger, B., Klünemann, M., Sieber, A., Uhlitz, F., Sauer, S., Garnett, M.J., Blüthgen, N. and Saez-Rodriguez, J.
Nature Communications 9 (1): 20. 2 January 2018

Loss-of-function uORF mutations in human malignancies.
Schulz, J., Mah, N., Neuenschwander, M., Kischka, T., Ratei, R., Schlag, P.M., Castaños-Vélez, E., Fichtner, I., Tunn, P.U., Denkert, C., Klaas, O., Berdel, W.E., von Kries, J.P., Makalowski, W., Andrade-Navarro, M.A., Leutz, A. and Wethmar, K.
Scientific Reports 8 (1): 2395. 5 February 2018

CellFy: a cell-based fragment screen against C-type lectins.
Schulze, J., Baukmann, H., Wawrzinek, R., Fuchsberger, F., Specker, E., Aretz, J., Nazaré, M. and Rademacher, C.
ACS Chemical Biology 13 (12): 3229-3235. December 2018

Telmisartan prevents diet-induced obesity and preserves leptin transport across the blood-brain barrier in high-fat diet-fed mice.
Schuster, F., Huber, G., Stölting, I., Wing, E.E., Saar, K., Hübner, N., Banks, W.A. and Raasch, W.
Pflugers Archiv 470 (11): 1673-1689. November 2018

The NutriAct Family Study: a web-based prospective study on the epidemiological, psychological and sociological basis of food choice.
Schwingshackl, L., Ruzanska, U., Anton, V., Wallroth, R., Ohla, K., Knüppel, S., Schulze, M.B., Pischon, T., Deutschbein, J., Schenk, L., Warschburger, P., Harttig, U., Boeing, H. and Bergmann, M.M.
BMC Public Health 18 (1): 963. 3 August 2018

Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex.
Scior, A., Buntru, A., Arnsburg, K., Ast, A., Iburg, M., Juenemann, K., Pigazzini, M.L., Mlody, B., Puchkov, D., Priller, J., Wanker, E.E., Prigione, A. and Kirstein, J.
EMBO Journal 37 (2): 282-299. 17 January 2018

Consequences of cathepsin C inactivation on membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
Seren, S., Rashed Abouzaid, M., Eulenberg-Gustavus, C., Hirschfeld, J., Soliman, H., Jerke, U., N'Guessan, K., Dallet-Choisy, S., Lesner, A., Lauritzen, C., Schacher, B., Eickholz, Pe., Nagy, N., Szell, M., Croix, C., Viaud-Massuard, M.C., Al Farraj Aldosari, A., Ragunatha, S., Ibrahim Mostafa, M., Giampieri, F., Battino, M., Cornillier, H., Lorette, G., Stephan, J.L., Goizet, C., Pedersen, J., Gauthier, F., Jenne, D.E., Marchand-Adam, S., Chapple, I.L., Kettritz, R. and Korkmaz, B.
Journal of Biological Chemistry 293 (32): 12415-12428. 10 August 2018

Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities.
Serresi, M., Siteur, B., Hulsman, D., Company, C., Schmitt, M.J., Lieftink, C., Morris, B., Cesaroni, M., Proost, N., Beijersbergen, R.L., van Lohuizen, M. and Gargiulo, G.
Journal of Experimental Medicine 215 (12): 3115. 3 December 2018

Pancreatic exocrine tissue architecture and integrity are maintained by e-cadherin during postnatal development.
Serrill, J.D., Sander, M. and Shih, H.P.
Scientific Reports 8 (1): 13451. 7 September 2018

Mechanoelectrical transduction in chondrocytes.
Servin-Vences, M.R., Richardson, J., Lewin, G.R. and Poole, K.
Clinical and Experimental Pharmacology & Physiology 45 (5): 481-488. May 2018

Human induced pluripotent stem cell production and expansion from blood using a non-integrating viral reprogramming vector.
Sharma, A., Mücke, M. and Seidman, C.E.
Current Protocols in Molecular Biology 122 (1): e58. April 2018

High-throughput identification of RNA nuclear enrichment sequences.
Shukla, C.J., McCorkindale, A.L., Gerhardinger, C., Korthauer, K.D., Cabili, M.N., Shechner, D.M., Irizarry, R.A., Maass, P. and Rinn, J.L.
EMBO Journal 37 (6): e98452. 15 March 2018

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification.
Simandi, Z., Horvath, A., Cuaranta-Monroy, I., Sauer, S., Deleuze, J.F. and Nagy, L.
Molecular and Cellular Endocrinology 471 : 51-62. 15 August 2018

Transfer of synthetic human chromosome into human induced pluripotent stem cells for biomedical applications.
Sinenko, S.A., Skvortsova, E.V., Liskovykh, M.A., Ponomartsev, S.V., Kuzmin, A.A., Khudiakov, A.A., Malashicheva, A.B., Alenina, N., Larionov, V., Kouprina, N. and Tomilin, A.N.
Cells 7 (12): 261. 8 December 2018

SuperDRUG2: a one stop resource for approved/marketed drugs.
Siramshetty, V.B., Eckert, O.A., Gohlke, B.O., Goede, A., Chen, Q., Devarakonda, P., Preissner, S. and Preissner, R.
Nucleic Acids Research 46 (D1): D1137-D1143. 4 January 2018

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells.
Smith, A.M., Depp, C., Ryan, B.J., Johnston, G.I., Alegre-Abarrategui, J., Evetts, S., Rolinski, M., Baig, F., Ruffmann, C., Simon, A.K., Hu, M.T.M. and Wade-Martins, R.
Movement Disorders 33 (10): 1580-1590. October 2018

Identification and treatment of the visual processing asymmetry in MS patients with optic neuritis: The Pulfrich phenomenon.
Sobhanian, M.J., Agarwal, R., Meltzer, E., Kildebeck, E., Frohman, B.S., Frohman, A.N., Galetta, S.L., Saidha, S., White, O., Villoslada, P., Paul, F., Petzold, A., Rennaker, R.L., Martinez-Lapiscina, E.H., Balcer, L.J., Kardon, R., Frohman, E.M. and Frohman, T.C.
Journal of the Neurological Sciences 387 : 60-69. 15 April 2018

Magnetic resonance imaging findings at the first episode of acute optic neuritis.
Soelberg, K., Skejoe, H.P.B., Grauslund, J., Smith, T.J., Lillevang, S.T., Jarius, S., Wildemann, B., Paul, F. and Asgari, N.
Multiple Sclerosis and Related Disorders 20 : 30-36. February 2018

Optical coherence tomography in acute optic neuritis: a population-based study.
Soelberg, K., Specovius, S., Zimmermann, H.G., Grauslund, J., Mehlsen, J.J., Olesen, C., Neve, A.S.B., Paul, F., Brandt, A.U. and Asgari, N.
Acta Neurologica Scandinavica 138 (6): 566-573. December 2018

A semi-supervised approach to discover bivariate causality in large biological data.
Sokolovska, N., Permiakova, O., Forslund, S.K. and Zucker, J.D.
Lecture Notes in Computer Science 10934 : 406-420. 8 July 2018

Nekroptose und ANCA-assoziierte Vaskulitis [Necroptosis and ANCA-associated vasculitis].
Sonnemann, J., Rousselle, A. and Schreiber, A.
Nephrologe 13 (1): 45-47. January 2018

Effect of delivery platforms structure on the epidermal antigen transport for topical vaccination.
Sonzogni, A.S., Yealland, G., Kar, M., Wedepohl, S., Gugliotta, L.M., Gonzalez, V.D.G., Hedtrich, S., Calderón, M. and Minari, R.J.
Biomacromolecules 19 (12): 4607-4616. 10 December 2018

Comparison of modified Matyash method to conventional solvent systems for polar metabolite and lipid extractions.
Sostare, J., Di Guida, R., Kirwan, J., Chalal, K., Palmer, E., Dunn, W.B. and Viant, M.R.
Analytica Chimica Acta 1037 : 301-315. 11 December 2018

Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
Sowa, A.S., Martin, E., Martins, I.M., Schmidt, J., Depping, R., Weber, J.J., Rother, F., Hartmann, E., Bader, M., Riess, O., Tricoire, H. and Schmidt, T.
Proceedings of the National Academy of Sciences of the United States of America 115 (11): E2624-E2633. 13 March 2018

Simultaneous lineage tracing and cell-type identification using CRISPR-Cas9-induced genetic scars.
Spanjaard, B., Hu, B., Mitic, N., Olivares-Chauvet, P., Janjuha, S., Ninov, N. and Junker, J.P.
Nature Biotechnology 36 (5): 469-473. May 2018

Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.
Stone, O.A., El-Brolosy, M., Wilhelm, K., Liu, X., Romão, A.M., Grillo, E., Lai, J.K.H., Günther, S., Jeratsch, S., Kuenne, C., Lee, I.C., Braun, T., Santoro, M.M., Locasale, J.W., Potente, M. and Stainier, D.Y.R.
Nature Communications 9 (1): 4077. 9 October 2018

Myocardial tissue characterization by contrast-enhanced cardiac magnetic resonance imaging in subjects with prediabetes, diabetes, and normal controls with preserved ejection fraction from the general population.
Storz, C., Hetterich, H., Lorbeer, R., Heber, S.D., Schafnitzel, A., Patscheider, H., Auweter, S., Zitzelsberger, T., Rathmann, W., Nikolaou, K., Reiser, M., Schlett, C.L., von Knobelsdorff-Brenkenhoff, F., Peters, A., Schulz-Menger, J. and Bamberg, F.
European Heart Journal - Cardiovascular Imaging 19 (6): 701-708. 1 June 2018

Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels.
Strasen, J., Sarma, U., Jentsch, M., Bohn, S., Sheng, C., Horbelt, D., Knaus, P., Legewie, S. and Loewer, A.
Molecular Systems Biology 14 (1): e7733. 25 January 2018

LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion.
Stuhlmann, T., Planells-Cases, R. and Jentsch, T.J.
Nature Communications 9 (1): 1974. 17 May 2018

Cannabinoid type 2 receptors mediate a cell type-specific self-inhibition in cortical neurons.
Stumpf, A., Parthier, D., Sammons, R.P., Stempel, A.V., Breustedt, J., Rost, B.R. and Schmitz, D.
Neuropharmacology 139 : 217-225. 1 September 2018

A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial).
Stürner, K.H., Stellmann, J.P., Dörr, J., Paul, F., Friede, T., Schammler, S., Reinhardt, S., Gellissen, S., Weissflog, G., Faizy, T.D., Werz, O., Fleischer, S., Vaas, L.A.I., Herrmann, F., Pless, O., Martin, R. and Heesen, C.
Journal of Neurology Neurosurgery and Psychiatry 89 (4): 330-338. 15 March 2018

SORCS1 and SORCS3 control energy balance and orexigenic peptide production.
Subkhangulova, A., Malik, A.R., Hermey, G., Popp, O., Dittmar, G., Rathjen, T., Poy, M.N., Stumpf, A., Beed, P.S., Schmitz, D., Breiderhoff, T. and Willnow, T.E.
EMBO Reports 19 (4): e44810. 1 April 2018

Metabolic labeling of newly synthesized RNA with 4sU to in parallel assess RNA transcription and decay.
Sun, W. and Chen, W.
Methods in Molecular Biology 1720 : 25-34. 2018

Pervasive allele-specific regulation on RNA decay in hybrid mice.
Sun, W., Gao, Q., Schaefke, B., Hu, Y. and Chen, W.
Life Science Alliance 1 (2): e201800052. May 2018

Involvement of mossy cells in sharp wave-ripple activity in vitro.
Swaminathan, A., Wichert, I., Schmitz, D. and Maier, N.
Cell Reports 23 (9): 2541-2549. 29 May 2018

Cystathionine γ-lyase-produced hydrogen sulfide controls endothelial NO bioavailability and blood pressure.
Szijártó, I.A., Markó, L., Filipovic, M.R., Miljkovic, J.L., Tabeling, C., Tsvetkov, D., Wang, N., Rabelo, L.A., Witzenrath, M., Diedrich, A., Tank, J., Akahoshi, N., Kamata, S., Ishii, I. and Gollasch, M.
Hypertension 71 (6): 1210-1217. June 2018

Loss of host-derived osteopontin creates a glioblastoma-promoting microenvironment.
Szulzewsky, F., Schwendinger, N., Güneykaya, D., Cimino, P.J., Hambardzumyan, D., Synowitz, M., Holland, E.C. and Kettenmann, H.
Neuro-Oncology 20 (3): 355-366. 19 February 2018

Hold me, but not too tight - endothelial cell-cell junctions in angiogenesis.
Szymborska, A. and Gerhardt, H.
Cold Spring Harbor Perspectives in Biology 10 (8): a029223. August 2018

A transgenic dual-luciferase reporter mouse for longitudinal and functional monitoring of T cells in vivo.
Szyska, M., Herda, S., Althoff, S., Heimann, A., Russ, J., D'Abundo, D., Dang, T.M., Durieux, I., Dörken, B., Blankenstein, T. and Na, I.K.
Cancer Immunology Research 6 (1): 110-120. January 2018

Haploinsufficiency of Insm1 impairs postnatal baseline β-cell mass.
Tao, W., Zhang, Y., Ma, L., Deng, C., Duan, H., Liang, X., Liao, R., Lin, S., Nie, T., Chen, W., Wang, C., Birchmeier, C. and Jia, S.
Diabetes 67 (12): 2615-2625. December 2018

Loss of axon bifurcation in mesencephalic trigeminal neurons impairs the maximal biting force in Npr2-deficient mice.
Ter-Avetisyan, G., Dumoulin, A., Herrel, A., Schmidt, H., Strump, J., Afzal, S. and Rathjen, F.G.
Frontiers in Cellular Neuroscience 12 : 153. 15 June 2018

Post-transcriptional regulation by 3' UTRs can be masked by regulatory elements in 5' UTRs.
Theil, K., Herzog, M. and Rajewsky, N.
Cell Reports 22 (12): 3217-3226. 20 March 2018

Voltage gated calcium channel activation by backpropagating action potentials downregulates NMDAR function.
Theis, A.K., Rózsa, B., Katona, G., Schmitz, D. and Johenning, F.W.
Frontiers in Cellular Neuroscience 12 : 109. 23 April 2018

Evaluating uncertainty in signaling networks using logical modeling.
Thobe, K., Kuznia, C., Sers, C. and Siebert, H.
Frontiers in Physiology 9 : 1335. October 2018

Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML.
Thol, F., Gabdoulline, R., Liebich, A., Klement, P., Schiller, J., Kandziora, C., Hambach, L., Stadler, M., Koenecke, C., Flintrop, M., Pankratz, M., Wichmann, M., Neziri, B., Büttner, K., Heida, B., Klesse, S., Chaturvedi, A., Kloos, A., Göhring, G., Schlegelberger, B., Gaidzik, V.I., Bullinger, L., Fiedler, W., Heim, A., Hamwi, I., Eder, M., Krauter, J., Schlenk, R.F., Paschka, P., Döhner, K., Döhner, H., Ganser, A. and Heuser, M.
Blood 132 (16): 1703-1713. 18 October 2018

Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone.
Tolkachov, A., Fischer, C., Ambrosi, T.H., Bothe, M., Han, C.T., Muenzner, M., Mathia, S., Salminen, M., Seifert, G., Thiele, M., Duda, G.N., Meijsing, S.H., Sauer, S., Schulz, T.J. and Schupp, M.
Molecular and Cellular Biology 38 (12): e00599-17. June 2018

User evaluation indicates high quality of the Surveillance Outbreak Response Management and Analysis System (SORMAS) after field deployment in Nigeria in 2015 and 2018.
Tom-Aba, D., Toikkanen, S.E., Glöckner, S., Adeoye, O., Mall, S., Fähnrich, C., Denecke, K., Benzler, J., Kirchner, G., Schwarz, N., Poggensee, G., Silenou, B.C., Ameh, C.A., Nguku, P., Olubunmi, O., Ihekweazu, C. and Krause, G.
Studies in Health Technology and Informatics 253 : 233-237. 2018

Nutritional preferences of human gut bacteria reveal their metabolic idiosyncrasies.
Tramontano, M., Andrejev, S., Pruteanu, M., Klünemann, M., Kuhn, M., Galardini, M., Jouhten, P., Zelezniak, A., Zeller, G., Bork, P., Typas, A. and Patil, K.R.
Nature Microbiology 3 (3): 514-522. April 2018

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Trepte, P., Kruse, S., Kostova, S., Hoffmann, S., Buntru, A., Tempelmeier, A., Secker, C., Diez, L., Schulz, A., Klockmeier, K., Zenkner, M., Golusik, S., Rau, K., Schnoegl, S., Garner, C.C. and Wanker, E.E.
Molecular Systems Biology 14 (7): e8071. 11 July 2018

The absence of sensory axon bifurcation affects nociception and termination fields of afferents in the spinal cord.
Tröster, P., Haseleu, J., Petersen, J., Drees, O., Schmidtko, A., Schwaller, F., Lewin, G.R., Ter-Avetisyan, G., Winter, Y., Peters, S., Feil, S., Feil, R., Rathjen, F.G. and Schmidt, H.
Frontiers in Molecular Neuroscience 11 : 19. 8 February 2018

Nrf2 regulates CD4(+) T cell-induced acute graft-versus-host disease in mice.
Tsai, J.J., Velardi, E., Shono, Y., Argyropoulos, K.V., Holland, A.M., Smith, O.M., Yim, N.L., Rao, U.K., Kreines, F.M., Lieberman, S.R., Young, L.F., Lazrak, A., Youssef, S., Fu, Y.Y., Liu, C., Lezcano, C., Murphy, G.F., Na, I.K., Jenq, R.R., Hanash, A.M., Dudakov, J.A. and van den Brink, M.R.M.
Blood 132 (26): 2763-2774. 27 December 2018

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal.
Turajlic, S., Xu, H., Litchfield, K., Rowan, A., Horswell, S., Chambers, T., O'Brien, T., Lopez, J.I., Watkins, T.B.K., Nicol, D., Stares, M., Challacombe, B., Hazell, S., Chandra, A., Mitchell, T.J., Au, L., Eichler-Jonsson, C., Jabbar, F., Soultati, A., Chowdhury, S., Rudman, S., Lynch, J., Fernando, A., Stamp, G., Nye, E., Stewart, A., Xing, W., Smith, J.C., Escudero, M., Huffman, A., Matthews, N., Elgar, G., Phillimore, B., Costa, M., Begum, S., Ward, S., Salm, M., Boeing, S., Fisher, R., Spain, L., Navas, C., Grönroos, E., Hobor, S., Sharma, S., Aurangzeb, I., Lall, S., Polson, A., Varia, M., Horsfield, C., Fotiadis, N., Pickering, L., Schwarz, R.F., Silva, B., Herrero, J., Luscombe, N.M., Jamal-Hanjani, M., Rosenthal, R., Birkbak, N.J., Wilson, G.A., Pipek, O., Ribli, D., Krzystanek, M., Csabai, I., Szallasi, Z., Gore, M., McGranahan, N., Van Loo, P., Campbell, P., Larkin, J. and Swanton, C.
Cell 173 (3): 595-610. 19 April 2018

The genetic landscape of diamond-blackfan anemia.
Ulirsch, J.C., Verboon, J.M., Kazerounian, S., Guo, M.H., Yuan, D., Ludwig, L.S., Handsaker, R.E., Abdulhay, N.J., Fiorini, C., Genovese, G., Lim, E.T., Cheng, A., Cummings, B.B., Chao, K.R., Beggs, A.H., Genetti, C.A., Sieff, C.A., Newburger, P.E., Niewiadomska, E., Matysiak, M., Vlachos, A., Lipton, J.M., Atsidaftos, E., Glader, B., Narla, A., Gleizes, P.E., O'Donohue, M.F., Montel-Lehry, N., Amor, D.J., McCarroll, S.A., O'Donnell-Luria, A.H., Gupta, N., Gabriel, S.B., MacArthur, D.G., Lander, E.S., Lek, M., Da Costa, L., Nathan, D.G., Korostelev, A.A., Do, R., Sankaran, V.G. and Gazda, H.T.
American Journal of Human Genetics 103 (6): 930-947. 6 December 2018

Precisely timed nicotinic activation drives SST inhibition in neocortical circuits.
Urban-Ciecko, J., Jouhanneau, J.S., Myal, S.E., Poulet, J.F.A. and Barth, A.L.
Neuron 97 (3): 611-625. 7 February 2018

Mutations in the BAF-complex subunit DPF2 are associated with Coffin-Siris syndrome.
Vasileiou, G., Vergarajauregui, S., Endele, S., Popp, B., Büttner, C., Ekici, A.B., Gerard, M., Bramswig, N.C., Albrecht, B., Clayton-Smith, J., Morton, J., Tomkins, S., Low, K., Weber, A., Wenzel, M., Altmüller, J., Li, Y., Wollnik, B., Hoganson, G., Plona, M.R., Cho, M.T., Thiel, C.T., Lüdecke, H.J., Strom, T.M., Calpena, E., Wilkie, A.O.M., Wieczorek, D., Engel, F.B. and Reis, A.
American Journal of Human Genetics 102 (3): 468-479. 1 March 2018

The first night effect in multiple sclerosis patients undergoing home-based polysomnography.
Veauthier, C., Piper, S.K., Gaede, G., Penzel, T. and Paul, F.
Nature and Science of Sleep 10 : 337-344. 23 October 2018

Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression.
Vion, A.C., Alt, S., Klaus-Bergmann, A., Szymborska, A., Zheng, T., Perovic, T., Hammoutene, A., Oliveira, M.B., Bartels-Klein, E., Hollfinger, I., Rautou, P.E., Bernabeu, M.O. and Gerhardt, H.
Journal of Cell Biology 217 (5): 1651-1665. 7 May 2018

ONS: an ontology for a standardized description of interventions and observational studies in nutrition.
Vitali, F., Lombardo, R., Rivero, D., Mattivi, F., Franceschi, P., Bordoni, A., Trimigno, A., Capozzi, F., Felici, G., Taglino, F., Miglietta, F., De Cock, N., Lachat, C., De Baets, B., De Tré, G., Pinart, M., Nimptsch, K., Pischon, T., Bouwman, J. and Cavalieri, D.
Genes & Nutrition 13 : 12. 30 April 2018

Brain-wide circuit interrogation at the cellular level guided by online analysis of neuronal function.
Vladimirov, N., Wang, C., Höckendorf, B., Pujala, A., Tanimoto, M., Mu, Y., Yang, C.T., Wittenbach, J.D., Freeman, J., Preibisch, S., Koyama, M., Keller, P.J. and Ahrens, M.B.
Nature Methods 15 (12): 1117-1125. December 2018

SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.
Voelkl, J., Luong, T.T., Tuffaha, R., Musculus, K., Auer, T., Lian, X., Daniel, C., Zickler, D., Boehme, B., Sacherer, M., Metzler, B., Kuhl, D., Gollasch, M., Amann, K., Müller, D.N., Pieske, B., Lang, F. and Alesutan, I.
Journal of Clinical Investigation 128 (7): 3024-3040. 2 July 2018

The effect of ARC ablation on skeletal muscle morphology, function, and apoptotic signaling during aging.
Vorobej, K., Mitchell, A.S., Smith, I.C., Donath, S., Tupling, A.R. and Quadrilatero, J.
Experimental Gerontology 101 : 69-79. January 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.
Waage, J., Standl, M., Curtin, J.A., Jessen, L.E., Thorsen, J., Tian, C., Schoettler, N., Flores, C., Abdellaoui, A., Ahluwalia, T.S., Alves, A.C., Amaral, A.F.S., Antó, J.M., Arnold, A., Barreto-Luis, A., Baurecht, H., van Beijsterveldt, C.E.M., Bleecker, E.R., Bonàs-Guarch, S., Boomsma, D.I., Brix, S., Bunyavanich, S., Burchard, E.G., Chen, Z., Curjuric, I., Custovic, A., den Dekker, H.T., Dharmage, S.C., Dmitrieva, J., Duijts, L., Ege, M.J., Gauderman, W.J., Georges, M., Gieger, C., Gilliland, F., Granell, R., Gui, H., Hansen, T., Heinrich, J., Henderson, J., Hernandez-Pacheco, N., Holt, P., Imboden, M., Jaddoe, V.W.V., Jarvelin, M.R., Jarvis, D.L., Jensen, K.K., Jónsdóttir, I., Kabesch, M., Kaprio, J., Kumar, A., Lee, Y.A., Levin, A.M., Li, X., Lorenzo-Diaz, F., Melén, E., Mercader, J.M., Meyers, D.A., Myers, R., Nicolae, D.L., Nohr, E.A., Palviainen, T., Paternoster, L., Pennell, C.E., Pershagen, G., Pino-Yanes, M., Probst-Hensch, N.M., Rüschendorf, F., Simpson, A., Stefansson, K., Sunyer, J., Sveinbjornsson, G., Thiering, E., Thompson, P.J., Torrent, M., Torrents, D., Tung, J.Y., Wang, C.A., Weidinger, S., Weiss, S., Willemsen, G., Williams, L.K., Ober, C., Hinds, D.A., Ferreira, M.A., Bisgaard, H., Strachan, D.P. and Bønnelykke, K.
Nature Genetics 50 (8): 1072-1080. August 2018

IG-MYC(+) neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas.
Wagener, R., López, C., Kleinheinz, K., Bausinger, J., Aukema, S.M., Nagel, I., Toprak, U.H., Seufert, J., Altmüller, J., Thiele, H., Schneider, C., Kolarova, J., Park, J., Hübschmann, D., Murga Penas, E.M., Drexler, H.G., Attarbaschi, A., Hovland, R., Kjeldsen, E., Kneba, M., Kontny, U., de Leval, L., Nürnberg, P., Oschlies, I., Oscier, D., Schlegelberger, B., Stilgenbauer, S., Wössmann, W., Schlesner, M., Burkhardt, B., Klapper, W., Jaffe, E.S., Küppers, R. and Siebert, R.
Blood 132 (21): 2280-2285. 22 November 2018

Self-assembly of mutant huntingtin exon-1 fragments into large complex fibrillar structures involves nucleated branching.
Wagner, A.S., Politi, A.Z., Ast, A., Bravo-Rodriguez, K., Baum, K., Buntru, A., Strempel, N.U., Brusendorf, L., Hänig, C., Boeddrich, A., Plassmann, S., Klockmeier, K., Ramirez-Anguita, J.M., Sanchez-Garcia, E., Wolf, J. and Wanker, E.E.
Journal of Molecular Biology 430 (12): 1725-1744. 8 June 2018

Specialized mechanoreceptor systems in rodent glabrous skin.
Walcher, J., Ojeda-Alonso, J., Haseleu, J., Oosthuizen, M.K., Rowe, A.H., Bennett, N.C. and Lewin, G.R.
Journal of Physiology 596 (20): 4995-5016. 15 October 2018

TRPM8 activation via 3-iodothyronamine blunts VEGF-induced transactivation of TRPV1 in human uveal melanoma cells.
Walcher, L., Budde, C., Böhm, A., Reinach, P.S., Dhandapani, P., Ljubojevic, N., Schweiger, M.W., von der Waydbrink, H., Reimers, I., Köhrle, J. and Mergler, S.
Frontiers in Pharmacology 9 : 1234. 13 November 2018

A combined in vivo HSC transduction/selection approach results in efficient and stable gene expression in peripheral blood cells in mice.
Wang, H., Richter, M., Psatha, N., Li, C., Kim, J., Liu, J., Ehrhardt, A., Nilsson, S.K., Cao, B., Palmer, D., Ng, P., Izsvák, Z., Haworth, K.G., Kiem, H.P., Papayannopoulou, T. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 8 : 52-64. 16 March 2018

Palmitic acid methyl ester and its relation to control of tone of human visceral arteries and rat aortas by perivascular adipose tissue.
Wang, N., Kuczmanski, A., Dubrovska, G. and Gollasch, M.
Frontiers in Physiology 9 : 583. May 2018

Bradykinin B2 receptor is essential to running-induced cell proliferation in the adult mouse hippocampus.
Wasinski, F., Oliveira Batista, R., Bader, M., Araujo, R.C. and Klempin, F.
Brain Structure & Function 223 (8): 3901-3907. November 2018

Phylogenetic quantification of intratumor heterogeneity.
Watkins, T.B.K. and Schwarz, R.F.
Cold Spring Harbor Perspectives in Medicine 8 (4): a028316. April 2018

Olfactory receptors as biomarkers in human breast carcinoma tissues.
Weber, L., Maßberg, D., Becker, C., Altmüller, J., Ubrig, B., Bonatz, G., Wölk, G., Philippou, S., Tannapfel, A., Hatt, H. and Gisselmann, G.
Frontiers in Oncology 8 : 33. 15 February 2018

BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer.
Weber-Lassalle, N., Hauke, J., Ramser, J., Richters, L., Groß, E., Blümcke, B., Gehrig, A., Kahlert, A.K., Müller, C.R., Hackmann, K., Honisch, E., Weber-Lassalle, K., Niederacher, D., Borde, J., Thiele, H., Ernst, C., Altmüller, J., Neidhardt, G., Nürnberg, P., Klaschik, K., Schroeder, C., Platzer, K., Volk, A.E., Wang-Gohrke, S., Just, W., Auber, B., Kubisch, C., Schmidt, G., Horvath, J., Wappenschmidt, B., Engel, C., Arnold, N., Dworniczak, B., Rhiem, K., Meindl, A., Schmutzler, R.K. and Hahnen, E.
Breast Cancer Research 20 (1): 7. 24 January 2018

Defective synapse maturation and enhanced synaptic plasticity in Shank2 Δex7(-/-) mice.
Wegener, S., Buschler, A., Stempel, A.V., Kang, S.J., Lim, C.S., Kaang, B.K., Shoichet, S.A., Manahan-Vaughan, D. and Schmitz, D.
eNeuro 5 (3): e0398-17.2018. 29 May 2018

Content-aware image restoration: pushing the limits of fluorescence microscopy.
Weigert, M., Schmidt, U., Boothe, T., Müller, A., Dibrov, A., Jain, A., Wilhelm, B., Schmidt, D., Broaddus, C., Culley, S., Rocha-Martins, M., Segovia-Miranda, F., Norden, C., Henriques, R., Zerial, M., Solimena, M., Rink, J., Tomancak, P., Royer, L., Jug, F. and Myers, E.W.
Nature Methods 15 (12): 1090-1097. December 2018

Temporally resolved parametric assessment of Z-magnetization recovery (TOPAZ): dynamic myocardial T(1) mapping using a cine steady-state look-locker approach.
Weingaertner, S., Shenoy, C., Rieger, B., Schad, L.R., Schulz-Menger, J. and Akçakaya, M.
Magnetic Resonance in Medicine 79 (4): 2087-2100. April 2018

Ectopic expression of transcription factor BATF3 induces B-cell lymphomas in a murine B-cell transplantation model.
Weiser, C., Petkova, M.V., Rengstl, B., Döring, C., von Laer, D., Hartmann, S., Küppers, R., Hansmann, M.L. and Newrzela, S.
Oncotarget 9 (22): 15942-15951. 23 March 2018

Exome sequencing in syndromic brain malformations identifies novel mutations in ACTB, and SLC9A6, and suggests BAZ1A as a new candidate gene.
Weitensteiner, V., Zhang, R., Bungenberg, J., Marks, M., Gehlen, J., Ralser, D.J., Hilger, A.C., Sharma, A., Schumacher, J., Gembruch, U., Merz, W.M., Becker, A., Altmüller, J., Thiele, H., Herrmann, B.G., Odermatt, B., Ludwig, M. and Reutter, H.
Birth Defects Research 110 (7): 587-597. 17 April 2018

Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization.
Weng, Q., Wang, J., Wang, J., Wang, J., Sattar, F., Zhang, Z., Zheng, J., Xu, Z., Zhao, M., Liu, X., Yang, L., Hao, G., Fang, L., Lu, Q.R., Yang, B. and He, Q.
Cell Death & Disease 9 (2): 251. 14 February 2018

Identification and characterization of a single high-affinity fatty acid binding site in human serum albumin.
Wenskowsky, L., Schreuder, H., Derdau, V., Matter, H., Volkmar, J., Nazaré, M., Opatz, T. and Petry, S.
Angewandte Chemie International Edition 57 (4): 1044-1048. 22 January 2018

Millimeter spatial resolution in vivo sodium MRI of the human eye at 7 T using a dedicated radiofrequency transceiver array.
Wenz, D., Kuehne, A., Huelnhagen, T., Nagel, A.M., Waiczies, H., Weinberger, O., Oezerdem, C., Stachs, O., Langner, S., Seeliger, E., Flemming, B., Hodge, R. and Niendorf, T.
Magnetic Resonance in Medicine 80 (2): 672-684. August 2018

Single molecule real time sequencing in ADTKD-MUC1 allows complete assembly of the VNTR and exact positioning of causative mutations.
Wenzel, A., Altmueller, J., Ekici, A.B., Popp, B., Stueber, K., Thiele, H., Pannes, A., Staubach, S., Salido, E., Nuernberg, P., Reinhardt, R., Reis, A., Rump, P., Hanisch, F.G., Wolf, M.T.F., Wiesener, M., Huettel, B. and Beck, B.B.
Scientific Reports 8 (1): 4170. 8 March 2018

Brain activity, regional gray matter loss, and decision-making in multiple sclerosis.
Weygandt, M., Wakonig, K., Behrens, J., Meyer-Arndt, L., Söder, E., Brandt, A.U., Bellmann-Strobl, J., Ruprecht, K., Gold, S.M., Haynes, J.D. and Paul, F.
Multiple Sclerosis Journal 24 (9): 1163-1173. 1 August 2018

Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.
Wilck, N., Markó, L., Balogh, A., Kräker, K., Herse, F., Bartolomaeus, H., Szijártó, I.A., Gollasch, M., Reichhart, N., Strauss, O., Heuser, A., Brockschnieder, D., Kretschmer, A., Lesche, R., Sohler, F., Stasch, J.P., Sandner, P., Luft, F., Müller, D.N., Dechend, R. and Haase, N.
JCI Insight 3 (4): e96006. 22 February 2018

Development of obesity can be prevented in rats by chronic icv infusions of AngII but less by Ang(1-7).
Winkler, M., Bader, M., Schuster, F., Stölting, I., Binder, S. and Raasch, W.
Pflugers Archiv 470 (6): 867-881. June 2018

Personalized risk prediction of postoperative cognitive impairment - rationale for the EU-funded BioCog project.
Winterer, G., Androsova, G., Bender, O., Boraschi, D., Borchers, F., Dschietzig, T.B., Feinkohl, I., Fletcher, P., Gallinat, J., Hadzidiakos, D., Haynes, J.D., Heppner, F., Hetzer, S., Hendrikse, J., Ittermann, B., Kant, I.M.J., Kraft, A., Krannich, A., Krause, R., Kühn, S., Lachmann, G., van Montfort, S.J.T., Müller, A., Nürnberg, P., Ofosu, K., Pietsch, M., Pischon, T., Preller, J., Renzulli, E., Scheurer, K., Schneider, R., Slooter, A.J.C., Spies, C., Stamatakis, E., Volk, H.D., Weber, S., Wolf, A., Yürek, F. and Zacharias, N.
European Psychiatry 50 : 34-39. April 2018

The effect of spermidine on memory performance in older adults at risk for dementia: a randomized controlled trial.
Wirth, M., Benson, G., Schwarz, C., Köbe, T., Grittner, U., Schmitz, D., Sigrist, S.J., Bohlken, J., Stekovic, S., Madeo, F. and Flöel, A.
Cortex 109 : 181-188. December 2018

Multi-view light-sheet imaging and tracking with the MaMuT software reveals the cell lineage of a direct developing arthropod limb.
Wolff, C., Tinevez, J.Y., Pietzsch, T., Stamataki, E., Harich, B., Guignard, L., Preibisch, S., Shorte, S., Keller, P.J., Tomancak, P. and Pavlopoulos, A.
eLife 7 : e34410. 29 March 2018

Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.
Wong, G.S., Zhou, J., Liu, J.B., Wu, Z., Xu, X., Li, T., Xu, D., Schumacher, S.E., Puschhof, J., McFarland, J., Zou, C., Dulak, A., Henderson, L., Xu, P., O'Day, E., Rendak, R., Liao, W.L., Cecchi, F., Hembrough, T., Schwartz, S., Szeto, C., Rustgi, A.K., Wong, K.K., Diehl, J.A., Jensen, K., Graziano, F., Ruzzo, A., Fereshetian, S., Mertins, P., Carr, S.A., Beroukhim, R., Nakamura, K., Oki, E., Watanabe, M., Baba, H., Imamura, Y., Catenacci, D. and Bass, A.J.
Nature Medicine 24 (7): 968-977. July 2018

Interaction modulation through arrays of clustered methyl-arginine protein modifications.
Woodsmith, J., Casado-Medrano, V., Benlasfer, N., Eccles, R.L., Hutten, S., Heine, C.L., Thormann, V., Abou-Ajram, C., Rocks, O., Dormann, D. and Stelzl, U.
Life Science Alliance 1 (5): e201800178. October 2018

Integrated in vivo quantitative proteomics and nutrient tracing reveals age-related metabolic rewiring of pancreatic β cell function.
Wortham, M., Benthuysen, J.R., Wallace, M., Savas, J.N., Mulas, F., Divakaruni, A.S., Liu, F., Albert, V., Taylor, B.L., Sui, Y., Saez, E., Murphy, A.N., Yates, J.R., Metallo, C.M. and Sander, M.
Cell Reports 25 (10): 2904-2918. 4 December 2018

VGLUT2 functions as a differential marker for hippocampal output neurons.
Wozny, C., Beed, P., Nitzan, N., Pössnecker, Y., Rost, B.R. and Schmitz, D.
Frontiers in Cellular Neuroscience 12 : 337. 2 October 2018

Der Genetiker Leo Sachs.
Wunderlich, V.
Aerzteblatt Sachsen 1 : 39-40. January 2018

PiGx: reproducible genomics analysis pipelines with GNU Guix.
Wurmus, R., Uyar, B., Osberg, B., Franke, V., Gosdschan, A., Wreczycka, K., Ronen, J. and Akalin, A.
GigaScience 7 (12): giy123. 1 December 2018

N(6)-methyladenine DNA modification in glioblastoma.
Xie, Q., Wu, T.P., Gimple, R.C., Li, Z., Prager, B.C., Wu, Q., Yu, Y., Wang, P., Wang, Y., Gorkin, D.U., Zhang, C., Dowiak, A.V., Lin, K., Zeng, C., Sui, Y., Kim, L.J.Y., Miller, T.E., Jiang, L., Lee, C.H., Huang, Z., Fang, X.., Zhai, K., Mack, S.C., Sander, M., Bao, S., Kerstetter-Fogle, A.E., Sloan, A.E., Xiao, A.Z. and Rich, J.N.
Cell 175 (5): 1228-1243. 15 November 2018

Predominant patterns of splicing evolution on human, chimpanzee, and macaque evolutionary lineages.
Xiong, J., Xi, J., Ditsiou, A., Gao, Y., Sun, J., Lowenstein, E.D., Huang, S. and Khaitovich, P.
Human Molecular Genetics 27 (8): 1474-1485. 15 April 2018

Optic nerve head three-dimensional shape analysis.
Yadav, S.K., Kadas, E.M., Motamedi, S., Polthier, K., Haußer, F., Gawlik, K., Paul, F. and Brandt, A.
Journal of Biomedical Optics 23 (10): 106004. October 2018

Neuronal cell adhesion molecule 1 regulates leptin sensitivity and bone mass.
Yan, X., Kononenko, N.L., Brueel, A., Thomsen, J.S. and Poy, M.N.
Calcified Tissue International 102 (3): 329-336. March 2018

Control of hepatic gluconeogenesis by Argonaute2.
Yan, X., Wang, Z., Bishop, C.A., Weitkunat, K., Feng, X., Tarbier, M., Luo, J., Friedländer, M.R., Burkhardt, R., Klaus, S., Willnow, T.E. and Poy, M.N.
Molecular Metabolism 18 : 15-24. December 2018

Cadm2 regulates body weight and energy homeostasis in mice.
Yan, X., Wang, Z., Schmidt, V., Gauert, A., Willnow, T.E., Heinig, M. and Poy, M.N.
Molecular Metabolism 8 : 180-188. February 2018

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
Yang, J.Y., Deng, X.Y., Li, Y.S., Ma, X.C., Feng, J.X., Yu, B., Chen, Y., Luo, Y.L., Wang, X., Chen, M.L., Fang, Z.X., Zheng, F.X., Li, Y.P., Zhong, Q., Kang, T.B., Song, L.B., Xu, R.H., Zeng, M.S., Chen, W., Zhang, H., Xie, W. and Gao, S.
Nature Communications 9 (1): 1165. 21 March 2018

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids.
Yoney, A., Etoc, F., Ruzo, A., Carroll, T., Metzger, J.J., Martyn, I., Li, S., Kirst, C., Siggia, E.D. and Brivanlou, A.H.
eLife 7 : e3827. 13 November 2018

Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma.
Yu, Y., Schleich, K., Yue, B., Ji, S., Lohneis, P., Kemper, K., Silvis, M.S., Qutob, N., van Rooijen, E., Werner-Klein, M., Li, L., Dhawan, D., Meierjohann, S., Reimann, M., Elkahloun, A., Treitschke, S., Dörken, B., Speck, C., Mallette, F.A., Zon, L.I., Holmen, S.L., Peeper, D.S., Samuels, Y., Schmitt, C.A. and Lee, S.
Cancer Cell 33 (2): 322-336. 12 February 2018

Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery.
Zabihi, F., Graff, P., Schumacher, F., Kleuser, B., Hedtrich, S. and Haag, R.
Nanoscale 10 (35): 16848-16856. 21 September 2018

High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds.
Zampieri, M., Szappanos, B., Buchieri, M.V., Trauner, A., Piazza, I., Picotti, P., Gagneux, S., Borrell, S., Gicquel, B., Lelievre, J., Papp, B. and Sauer, U.
Science Translational Medicine 10 (429): eaal3973. 21 February 2018

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender, A., Huang, J., Györfi, A.H., Matei, A.E., Trinh-Minh, T., Xu, X., Li, Y.N., Chen, C.W., Lin, J., Dees, C., Beyer, C., Gelse, K., Zhang, Z.Y., Bergmann, C., Ramming, A., Birchmeier, W., Distler, O., Schett, G. and Distler, J.H.W.
Nature Communications 9 (1): 3259. 14 August 2018

Hologenomic adaptations underlying the evolution of sanguivory in the common vampire bat.
Zepeda Mendoza, M.L., Xiong, Z., Escalera-Zamudio, M., Runge, A.K., Thézé, J., Streicker, D., Frank, H.K., Loza-Rubio, E., Liu, S., Ryder, O.A., Samaniego Castruita, J.A., Katzourakis, A., Pacheco, G., Taboada, B., Löber, U., Pybus, O.G., Li, Y., Rojas-Anaya, E., Bohmann, K., Carmona Baez, A., Arias, C.F., Liu, S., Greenwood, A.D., Bertelsen, M.F., White, N.E., Bunce, M., Zhang, G., Sicheritz-Pontén, T. and Gilbert, M.P.T.
Nature Ecology & Evolution 2 (4): 659-668. April 2018

LRRC8 amino-termini influence pore properties and gating of volume-regulated VRAC anion channels.
Zhou, P., Polovitskaya, M.M. and Jentsch, T.J.
Journal of Biological Chemistry 293 (35): 13440-13451. 31 August 2018

Association of retinal ganglion cell layer thickness with future disease activity in patients with clinically isolated syndrome.
Zimmermann, H.G., Knier, B., Oberwahrenbrock, T., Behrens, J., Pfuhl, C., Aly, L., Kaminski, M., Hoshi, M.M., Specovius, S., Giess, R.M., Scheel, M., Mühlau, M., Bellmann-Strobl, J., Ruprecht, K., Hemmer, B., Korn, T., Paul, F. and Brandt, A.U.
JAMA Neurology 75 (9): 1071-1079. September 2018

Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization of the molecular subtype.
Zinnall, U., Weyerer, V., Compérat, E., Camparo, P., Gaisa, N.T., Knuechel-Clarke, R., Perren, A., Lugli, A., Toma, M., Baretton, G., Kristiansen, G., Wirtz, R.M., Cheng, L., Wullich, B., Stoehr, R., Hartmann, A. and Bertz, S.
Human Pathology 80 : 55-64. October 2018

HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types.
Zirkel, A., Nikolic, M., Sofiadis, K., Mallm, J.P., Brackley, C.A., Gothe, H., Drechsel, O., Becker, C., Altmüller, J., Josipovic, N., Georgomanolis, T., Brant, L., Franzen, J., Koker, M., Gusmao, E.G., Costa, I.G., Ullrich, R.T., Wagner, W., Roukos, V., Nürnberg, P., Marenduzzo, D., Rippe, K. and Papantonis, A.
Molecular Cell 70 (4): 730-744.e6. 17 May 2018

Single-cell transcriptomics characterizes cell types in the subventricular zone and uncovers molecular defects impairing adult neurogenesis.
Zywitza, V., Misios, A., Bunatyan, L., Willnow, T.E. and Rajewsky, N.
Cell Reports 25 (9): 2457-2469. 27 November 2018

Cardioprotective effect of thyroid hormone is mediated by AT2 receptor and involves nitric oxide production via Akt activation in mice.
da Silva, I.B., Gomes, D.A., Alenina, N., Bader, M., dos Santos, R.A. and Barreto-Chaves, M.L.M.
Heart and Vessels 33 (6): 671-681. June 2018

Alamandine acts via MrgD to induce AMPK/NO activation against Ang II hypertrophy in cardiomyocytes.
de Jesus, I.C.G., Scalzo, S., Alves, F., Marques, K., Rocha-Resende, C., Bader, M., Santos, R.A.S. and Guatimosim, S.
American Journal of Physiology Cell Physiology 314 (6): C702-C711. June 2018

A de novo KCNA1 mutation in a patient with tetany and hypomagnesemia.
van der Wijst, J., Konrad, M., Verkaart, S.A.J., Tkaczyk, M., Latta, F., Altmüller, J., Thiele, H., Beck, B., Schlingmann, K.P. and de Baaij, J.H.F.
Nephron 139 (4): 359-366. August 2018

Treatment choices and neuropsychological symptoms of a large cohort of early MS.
von Bismarck, O., Dankowski, T., Ambrosius, B., Hessler, N., Antony, Gi., Ziegler, A., Hoshi, M.M., Aly, L., Luessi, F., Groppa, S., Klotz, L., Meuth, S.G., Tackenberg, B., Stoppe, M., Then Bergh, F., Tumani, H., Kümpfel, T., Stangel, M., Heesen, C., Wildemann, B., Paul, F., Bayas, A., Warnke, C., Weber, F., Linker, R.A., Ziemann, U., Zettl, U.K., Zipp, F., Wiendl, H., Hemmer, B., Gold, R. and Salmen, A.
Neurology Neuroimmunology & Neuroinflammation 5 (3): e446. 1 May 2018

Book Section

Information flow in a mammalian signal transduction pathway.
Benary, M., Nolis, I., Blüthgen, N. and Loewer, A.
In: Information- and Communication Theory in Molecular Biology. Lecture Notes in Bioengineering . Springer, Cham, Switzerland, 101-114. ISBN 978-3-319-54728-2 2018

Genome engineering using Sleeping Beauty transposition in vertebrates.
Chilkunda, S.S., Raghunathan, V., Narayanavari, S.A., Ivics, Z. and Izsvák, Z.
In: Genome editing and engineering. Cambridge University Press, Cambridge, 249-269. ISBN 9781316756300 July 2018

Quantification of myocardial effective transverse relaxation time with magnetic resonance at 7.0 tesla for a better understanding of myocardial (patho)physiology.
Huelnhagen, T., Serradas-Duarte, Teresa, Hezel, Fabian, Paul, K. and Niendorf, T.
In: Quantification of Biophysical Parameters in Medical Imaging. Springer, Cham, Switzerland, 343-372. ISBN 978-3-319-65923-7 2018

Microbiome and diseases: colorectal cancer.
Iftekhar, A., Sperlich, A., Janssen, K.P. and Sigal, M.
In: The Gut Microbiome in Health and Disease. Springer, Cham, 231-249. ISBN 978-3-319-90544-0 2018

Engineering of human-induced pluripotent stem cells for precise disease modeling.
Lisowski, P.
In: Stem Cell Genetics for Biomedical Research: Past, Present, and Future. Springer, Cham, Switzerland, 369-411. ISBN 978-3-319-90694-2 2018

Toward living nanomachines.
Mast, C., Möller, F., Kreysing, M., Schink, S., Obermayer, B., Gerland, U. and Braun, D.
In: Living machines: a handbook of research in biomimetics and biohybrid systems. Oxford University Press, Oxford, 380-389. ISBN 9780199674923 2018

Spatial organization of the nucleus compartmentalizes and regulates the genome.
Robson, M.I., Rizzotto, A. and Schirmer, E.C.
In: Nuclear Pore Complexes in Genome Organization, Function and Maintenance. Springer Cham, 1-34. ISBN 9783319716145 3 February 2018

Deciphering the universe of RNA structures and trans RNA-RNA interactions of transcriptomes in vivo: from experimental protocols to computational analyses.
Stefanov, S.R. and Meyer, I.M.
In: Systems Biology. RNA Technologies . Springer, Cham, 173-216. ISBN 978-3-319-92966-8 2018

Open source medical devices for innovation, education and global health: case study of open source magnetic resonance imaging.
Winter, L., Pellicer-Guridi, R., Broche, L., Winkler, S.A., Reimann, H., Han, H., Arndt, F., Hodge, R., Günyar, S., Moritz, M., Ettinger, K.M., de Fresnoye, O., Niendorf, T. and Benchoufi, M.
In: Co-creation : reshaping business and society in the era of bottom-up economics. Management for Professionals . Springer, Cham, 147-163. ISBN 978-3-319-97787-4 27 November 2018

Conference or Workshop Item

Near infrared spectroscopy setup for concurrent spectroscopic, invasive and MRI investigations in rats.
Gladytz, T., Hoppe, A., Cantow, K., Brix, S., Flemming, B., Pohlmann, A., Seeliger, E., Niendorf, T. and Grosenick, D.
In: Clinical and Translational Biophotonics, 3-6 April 2018, Los Angeles, United States of Amerika. 2018

A hybrid quantum-classical modeling approach for electrically driven quantum light sources.
Kantner, M., Mittnenzweig, M. and Koprucki, T.
In: Physics and Simulation of Optoelectronic Devices XXVI, 27 Jan - 01 Feb 2018, San Francisco, CA, USA. 23 February 2018

Patent

Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same.
Max-Delbrück-Centrum für Molekulare Medizin.
201615552556. 22 February 2018

Review

Addressing the perfect storm: biomarkers in obesity and pathophysiology of cardiometabolic risk.
Aleksandrova, K., Mozaffarian, D. and Pischon, T.
Clinical Chemistry 64 (1): 142-153. January 2018

The Meaning of Mas.
Bader, M., Alenina, N., Young, D., Santos, R.A.S. and Touyz, R.M.
Hypertension 72 (5): 1072-1075. November 2018

Allosteric modulators targeting CNS muscarinic receptors.
Bock, A., Schrage, R. and Mohr, K.
Neuropharmacology 136 (Part C): 427-437. 1 July 2018

Epigenetic therapy: azacytidine and decitabine in acute myeloid leukemia.
Bohl, S.R., Bullinger, L. and Rücker, F.G.
Expert Review of Hematology 11 (5): 361-371. May 2018

Neuromyelitis optica spectrum disorders and pregnancy: relapse-preventive measures and personalized treatment strategies.
Borisow, N., Hellwig, K. and Paul, F.
EPMA Journal 9 (3): 249-256. September 2018

Neuromyelitis-optica-Spektrum-Erkrankung und Schwangerschaft [Neuromyelitis optica spectrum disorder and pregnancy].
Borisow, N., Hellwig, K. and Paul, F.
Nervenarzt 89 (6): 666-673. June 2018

Diagnosis and treatment of NMO spectrum disorder and MOG-encephalomyelitis.
Borisow, N., Mori, M., Kuwabara, S., Scheel, M. and Paul, F.
Frontiers in Neurology 9 : 888. October 2018

Ten things you should know about transposable elements.
Bourque, G., Burns, K.H., Gehring, M., Gorbunova, V., Seluanov, A., Hammell, M., Imbeault, M., Izsvák, Z., Levin, H.L., Macfarlan, T.S., Mager, D.L. and Feschotte, C.
Genome Biology 19 (1): 199. 19 November 2018

Perivascular adipose tissue: the sixth man of the cardiovascular system.
Cheng, C.K., Bakar, H.A., Gollasch, M. and Huang, Y.
Cardiovascular Drugs and Therapy 32 (5): 481-502. October 2018

Enterotypes in the landscape of gut microbial community composition.
Costea, P.I., Hildebrand, F., Manimozhiyan, A., Baeckhed, F., Blaser, M.J., Bushman, F.D., de Vos, W.M., Ehrlich, S.D., Fraser, C.M., Hattori, M., Huttenhower, C., Jeffery, I.B., Knights, D., Lewis, J.D., Ley, R.E., Ochman, H., O'Toole, P.W., Quince, C., Relman, D.A., Shanahan, F., Sunagawa, S., Wang, J., Weinstock, G.M., Wu, G.D., Zeller, G., Zhao, L., Raes, J., Knight, R. and Bork, P.
Nature Microbiology 3 (1): 8-16. January 2018

Artificial gene regulatory networks-a review.
Cussat-Blanc, S., Harrington, K. and Banzhaf, W.
Artificial Life 24 (4): 296-328. 2018

Molecular analysis of sensory axon branching unraveled a cGMP-dependent signaling cascade.
Dumoulin, A., Ter-Avetisyan, G., Schmidt, H. and Rathjen, F.G.
International Journal of Molecular Sciences 19 (5): 1266. 24 April 2018

Roles of A-kinase anchoring proteins and phosphodiesterases in the cardiovascular system.
Ercu, M. and Klussmann, E.
Journal of Cardiovascular Development and Disease 5 (1): 14. 20 February 2018

Struktur und Funktion des mechanochemischen Motorproteins Dynamin.
Faelber, K. and Daumke, O.
BIOspektrum 24 (5): 481-483. September 2018

Associations of dyslipidaemia and lipid-lowering treatment with risk of postoperative cognitive dysfunction: a systematic review and meta-analysis.
Feinkohl, I., Winterer, G. and Pischon, T.
Journal of Epidemiology and Community Health 72 (6): 499-506. 10 May 2018

Cardiovascular magnetic resonance in nonischemic myocardial inflammation: expert recommendations.
Ferreira, V.M., Schulz-Menger, J., Holmvang, G., Kramer, C.M., Carbone, I., Sechtem, U., Kindermann, I., Gutberlet, M., Cooper, L.T., Liu, P. and Friedrich, M.G.
Journal of the American College of Cardiology 72 (24): 3158-3176. 18 December 2018

Circular RNAs: a new class of biomarkers as a rising interest in laboratory medicine.
Franz, A., Rabien, A., Stephan, C., Ralla, B., Fuchs, S., Jung, K. and Fendler, A.
Clinical Chemistry and Laboratory Medicine 56 (12): 1992-2003. December 2018

Next-generation in vivo modeling of human cancers.
Gargiulo, G.
Frontiers in Oncology 8 : 429. October 2018

The current role of MRI in differentiating multiple sclerosis from its imaging mimics.
Geraldes, R., Ciccarelli, O., Barkhof, F., De Stefano, N., Enzinger, C., Filippi, M., Hofer, M., Paul, F., Preziosa, P., Rovira, A., DeLuca, G.C., Kappos, L., Yousry, T., Fazekas, F., Frederiksen, J., Gasperini, C., Sastre-Garriga, J., Evangelou, N. and Palace, J.
Nature Reviews Neurology 14 (4): 199-213. April 2018

Perivascular adipose tissue and the dynamic regulation of K(V)7 and K(ir) channels: implications to resistant hypertension.
Gollasch, M., Welsh, D.G. and Schubert, R.
Microcirculation 25 (1): e12434. January 2018

The CRISPR/Cas9 system sheds new lights on the biology of protozoan parasites.
Grzybek, M., Golonko, A., Górska, A., Szczepaniak, K., Strachecka, A., Lass, A. and Lisowski, P.
Applied Microbiology and Biotechnology 102 (11): 4629-4640. June 2018

Developmental and functional heterogeneity of monocytes.
Guilliams, M., Mildner, A. and Yona, S.
Immunity 49 (4): 595-613. 16 October 2018

Causes and consequences of hematopoietic stem cell heterogeneity.
Haas, S., Trumpp, A. and Milsom, M.D.
Cell Stem Cell 22 (5): 627-638. 3 May 2018

Impacts of microbiome metabolites on immune regulation and autoimmunity.
Haase, S., Haghikia, A., Wilck, N., Müller, D.N. and Linker, R.A.
Immunology 154 (2): 230-238. June 2018

Emerging functions of DNA transposases and oncogenic mutators in childhood cancer development.
Henssen, A.G. and Kentsis, A.
JCI Insight 3 (20): 123172. 18 October 2018

Development of clinical simultaneous SPECT/MRI.
Hutton, B.F., Occhipinti, M., Kuehne, A., Máthé, D., Kovács, N., Waiczies, H., Erlandsson, K., Salvado, D., Carminati, M., Montagnani, G., Short, S., Ottobrini, L., van Mullekom, P., Piemonte, C., Bukki, T., Nyitrai, Z., Papp, Z., Nagy, K., Niendorf, T., de Francesco, I. and Fiorini, C.
British Journal of Radiology 91 (1081): 20160690. January 2018

Bacterial RNA biology on a genome scale.
Hör, J., Gorski, S.A. and Vogel, J.
Molecular Cell 70 (5): 785-799. 7 June 2018

MOG-Enzephalomyelitis: Internationale Empfehlungen zu Diagnose und Antikörpertestung [MOG encephalomyelitis: international recommendations on diagnosis and antibody testing].
Jarius, S., Paul, F., Aktas, O., Asgari, N., Dale, R.C., de Seze, J., Franciotta, D., Fujihara, K., Jacob, A., Kim, H.J., Kleiter, I., Kümpfel, T., Levy, M., Palace, J., Ruprecht, K., Saiz, A., Trebst, C., Weinshenker, B.G. and Wildemann, B.
Nervenarzt 89 (12): 1388-1399. December 2018

MOG encephalomyelitis: international recommendations on diagnosis and antibody testing.
Jarius, S., Paul, F., Aktas, O., Asgari, N., Dale, R.C., de Seze, J., Franciotta, D., Fujihara, K., Jacob, A., Kim, H.J., Kleiter, I., Kümpfel, T., Levy, M., Palace, J., Ruprecht, K., Saiz, A., Trebst, C., Weinshenker, B.G. and Wildemann, B.
Journal of Neuroinflammation 15 (1): 134. 3 May 2018

MOG-IgG in primary and secondary chronic progressive multiple sclerosis: a multicenter study of 200 patients and review of the literature.
Jarius, S., Ruprecht, K., Stellmann, J.P., Huss, A., Ayzenberg, I., Willing, A., Trebst, C., Pawlitzki, M., Abdelhak, A., Grüter, T., Leypoldt, F., Haas, J., Kleiter, I., Tumani, H., Fechner, K., Reindl, M., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 15 (1): 88. 19 March 2018

Bevacizumab in temozolomide refractory high-grade gliomas: single-centre experience and review of the literature.
Jeck, J., Kassubek, R., Coburger, J., Edenhofer, S., Schönsteiner, S.S., Ludolph, A.C., Schmitz, B., Engelke, J., Mayer-Steinacker, R., Lewerenz, J. and Bullinger, L.
Therapeutic Advances in Neurological Disorders 11 : 1756285617753597. 21 January 2018

CLC chloride channels and transporters: structure, function, physiology, and disease.
Jentsch, T.J. and Pusch, M.
Physiological Reviews 98 (3): 1493-1590. July 2018

Preanalytical processing and biobanking procedures of biological samples for metabolomics research: a white paper, community perspective (for "Precision Medicine and Pharmacometabolomics Task Group"-The Metabolomics Society Initiative).
Kirwan, J.A., Brennan, L., Broadhurst, D., Fiehn, O., Cascante, M., Dunn, W.B., Schmidt, M.A. and Velagapudi, V.
Clinical Chemistry 64 (8): 1158-1182. August 2018

Therapeutic targeting of cathepsin C: from pathophysiology to treatment.
Korkmaz, B., Caughey, G.H., Chapple, I., Gauthier, F., Hirschfeld, J., Jenne, D.E., Kettritz, R., Lalmanach, G., Lamort, A.S., Lauritzen, C., Legowska, M., Lesner, A., Marchand-Adam, S., McKaig, S.J., Moss, C., Pedersen, J., Roberts, H., Schreiber, A., Seren, S. and Thakkar, N.S.
Pharmacology & Therapeutics 190 : 202-236. October 2018

The growth and evolution of cardiovascular magnetic resonance: a 20-year history of the Society for Cardiovascular Magnetic Resonance (SCMR) annual scientific sessions.
Lee, D.C., Markl, M., Dall'Armellina, E., Han, Y., Kozerke, S., Kuehne, T., Nielles-Vallespin, S., Messroghli, D., Patel, A., Schaeffter, T., Simonetti, O., Valente, A.M., Weinsaft, J.W., Wright, G., Zimmerman, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 20 (1): 8. 31 January 2018

Mitochondria and the dynamic control of stem cell homeostasis.
Lisowski, P., Kannan, P., Mlody, B. and Prigione, A.
EMBO Reports 19 (5): e45432. 1 May 2018

Alternatives to animal testing in basic and preclinical research of atopic dermatitis.
Löwa, A., Jevtić, M., Gorreja, F. and Hedtrich, S.
Experimental Dermatology 27 (5): 476-483. May 2018

Peripheral serotonin synthesis as a new drug target.
Matthes, S. and Bader, M.
Trends in Pharmacological Sciences 39 (6): 560-572. June 2018

Synthetic embryology: controlling geometry to model early mammalian development.
Metzger, J.J., Simunovic, M. and Brivanlou, A.H.
Current Opinion in Genetics & Development 52 : 86-91. October 2018

The Senescence-Stemness Alliance - a cancer-hijacked regeneration principle.
Milanovic, M., Yu, Y. and Schmitt, C.A.
Trends in Cell Biology 28 (12): 1049-1061. December 2018

MOG antibody disease: a review of MOG antibody seropositive neuromyelitis optica spectrum disorder.
Narayan, R., Simpson, A., Fritsche, K., Salama, S., Pardo, S., Mealy, M., Paul, F. and Levy, M.
Multiple Sclerosis and Related Disorders 25 : 66-72. October 2018

Is timing important? The role of diet and lifestyle during early life on colorectal neoplasia.
Nimptsch, K. and Wu, K.
Current Colorectal Cancer Reports 14 (1): 1-11. February 2018

Socio-economic determinants of physical activity across the life course: a "DEterminants of DIet and Physical ACtivity" (DEDIPAC) umbrella literature review.
O'Donoghue, G., Kennedy, A., Puggina, A., Aleksovska, K., Buck, C., Burns, C., Cardon, G., Carlin, A., Ciarapica, D., Colotto, M., Condello, G., Coppinger, T., Cortis, C., D'Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Ling, F., Luzak, A., Napolitano, G., Nazare, J.A., Perchoux, C., Pesce, C., Pischon, T., Polito, A., Sannella, A., Schulz, H., Simon, C., Sohun, R., Steinbrecher, A., Schlicht, W., MacDonncha, C., Capranica, L. and Boccia, S.
PLoS ONE 13 (1): e0190737. 19 January 2018

Optical coherence tomography in neuromyelitis optica spectrum disorders: potential advantages for individualized monitoring of progression and therapy.
Oertel, F.C., Zimmermann, H., Paul, F. and Brandt, A.U.
EPMA Journal 9 (1): 21-33. March 2018

Investigational drugs in development to prevent neuromyelitis optica relapses.
Paul, F., Murphy, O., Pardo, S. and Levy, M.
Expert Opinion on Investigational Drugs 27 (3): 265-271. March 2018

Policy determinants of physical activity across the life course: a 'DEDIPAC' umbrella systematic literature review.
Puggina, A., Aleksovska, K., Buck, C., Burns, C., Cardon, G., Carlin, A., Chantal, S., Ciarapica, D., Condello, G., Coppinger, T., Cortis, C., D'Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Kennedy, A., Chun Man Ling, F., Luzak, A., Napolitano, G., Nazare, J.A., Perchoux, C., Pischon, T., Polito, A., Sannella, A., Schulz, H., Sohun, R., Steinbrecher, A., Schlicht, W., Ricciardi, W., MacDonncha, C., Capranica, L. and Boccia, S.
European Journal of Public Health 28 (1): 105-118. 1 February 2018

Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification.
Puntmann, V.O., Valbuena, S., Hinojar, R., Petersen, S.E., Greenwood, J.P., Kramer, C.M., Kwong, R.Y., McCann, G.P., Berry, C. and Nagel, E.
Journal of Cardiovascular Magnetic Resonance 20 (1): 67. 20 September 2018

Kinin B1 receptors as a therapeutic target for inflammation.
Qadri, F. and Bader, M.
Expert Opinion on Therapeutic Targets 22 (1): 31-44. January 2018

Improved molecular platform for the gene therapy of rare diseases by liver protein secretion.
Quiviger, M., Giannakopoulos, A., Verhenne, S., Marie, C., Stavrou, E.F., Vanhoorelbeke, K., Izsvák, Z., De Meyer, S.F., Athanassiadou, A. and Scherman, D.
European Journal of Medical Genetics 61 (11): 723-728. November 2018

MACC1 - the first decade of a key metastasis molecule from gene discovery to clinical translation.
Radhakrishnan, H., Walther, W., Zincke, F., Kobelt, D., Imbastari, F., Erdem, M., Kortüm, B., Dahlmann, M. and Stein, U.
Cancer and Metastasis Reviews 37 (4): 805-820. December 2018

Ozanimod for the treatment of relapsing remitting multiple sclerosis.
Rasche, L. and Paul, F.
Expert Opinion on Pharmacotherapy 19 (18): 2073-2086. December 2018

Transdifferentiation: do transition states lie on the path of development?
Reid, A. and Tursun, B.
Current Opinion in Systems Biology 11 : 18-23. October 2018

Local exchange of metabolites shapes immunity.
Richter, F.C., Obba, S. and Simon, A.K.
Immunology 155 (3): 309-319. November 2018

Autophagy dictates metabolism and differentiation of inflammatory immune cells.
Riffelmacher, T., Richter, F.C. and Simon, A.K.
Autophagy 14 (2): 199-206. 2018

The ACE2/angiotensin-(1-7)/MAS axis of the renin-angiotensin system: focus on angiotensin-(1-7).
Santos, R.A.S., Sampaio, W.O., Alzamora, A.C., Motta-Santos, D., Alenina, N., Bader, M. and Campagnole-Santos, M.J.
Physiological Reviews 98 (1): 505-553. January 2018

Epigenetic modulation of vascular diseases: assessing the evidence and exploring the opportunities.
Schiattarella, G.G., Madonna, R., Van Linthout, S., Thum, T., Schulz, R., Ferdinandy, P. and Perrino, C.
Vascular Pharmacology 107 : 43-52. August 2018

Nicht-Vitamin-K-abhängige orale Antikoagulanzien (NOAK) bei chronischer Niereninsuffizienz [Non-vitamin K antagonist oral anticoagulants (NOAC) in chronic kidney disease].
Schlieper, G., Remppis, A., Schwenger, V., Keller, T., Dechend, R., Massberg, S., Baldus, S., Weinreich, T., Hetzel, G., Floege, J., Hoyer, J., Mahfoud, F. and Fliser, D.
Nephrologe 13 (2): 91-98. March 2018

The human gut microbiome: from association to modulation.
Schmidt, T.S.B., Raes, J. and Bork, P.
Cell 172 (6): 1198-1215. 8 March 2018

Therapeutic potential of omega-3 fatty acid-derived epoxyeicosanoids in cardiovascular and inflammatory diseases.
Schunck, W.H., Konkel, A., Fischer, R. and Weylandt, K.H.
Pharmacology & Therapeutics 183 : 177-204. March 2018

Nonclinical data supporting orphan medicinal product designations: lessons from rare neurological conditions.
Sheean, M.E., Stoyanova-Beninska, V., Capovilla, G., Duarte, D., Hofer, M.P., Hoffmann, M., Magrelli, A., Mariz, S., Tsigkos, S., Shaili, E., Polsinelli, B., Ricciardi, M., Bonelli, M., Balabanov, P., Larsson, K. and Sepodes, B.
Drug Discovery Today 23 (1): 26-48. January 2018

Age reprogramming and epigenetic rejuvenation.
Singh, P.B. and Newman, A.G.
Epigenetics & Chromatin 11 (1): 73. 20 December 2018

Future brain and spinal cord volumetric imaging in the clinic for monitoring treatment response in MS.
Sinnecker, T., Granziera, C., Wuerfel, J. and Schlaeger, R.
Current Treatment Options in Neurology 20 (6): 17. June 2018

Drugs as habitable planets in the space of dark chemical matter.
Siramshetty, V.B. and Preissner, R.
Drug Discovery Today 23 (3): 481-486. March 2018

Structural variation in the 3D genome.
Spielmann, M., Lupiáñez, D.G. and Mundlos, S.
Nature Reviews Genetics 19 (7): 453-467. July 2018

The role of ethics in data governance of large neuro-ICT projects.
Stahl, B.C., Rainey, S., Harris, E. and Fothergill, B.T.
Journal of the American Medical Informatics Association 25 (8): 1099-1107. August 2018

Deep learning of genomic variation and regulatory network data.
Telenti, A., Lippert, C., Chang, P.C. and DePristo, M.
Human Molecular Genetics 27 (R1): R63-R71. 1 May 2018

Establishing rarity in the context of orphan medicinal product designation in the European Union.
Tsigkos, S., Hoffer, M.P., Sheean, M.E., Mariz, S., Larsson, K., Naumann-Winter, F., Fregonese, L. and Sepodes, B.
Drug Discovery Today 23 (3): 681-686. March 2018

Oncogenic MYD88 mutations in lymphoma: novel insights and therapeutic possibilities.
Weber, A.N.R., Cardona Gloria, Y., Çınar, Ö., Reinhardt, H.C., Pezzutto, A. and Wolz, O.O.
Cancer Immunology Immunotherapy 67 (11): 1797-1807. November 2018

The interstitium conducts extrarenal storage of sodium and represents a third compartment essential for extracellular volume and blood pressure homeostasis.
Wiig, H., Luft, F.C. and Titze, J.
Acta Physiologica 222 (3): e13006. March 2018

Discovering novel hydrolases from hot environments.
Wohlgemuth, R., Littlechild, J., Monti, D., Schnorr, K., van Rossum, T., Siebers, B., Menzel, P., Kublanov, I.V., Rike, A.G., Skretas, G., Szabo, Z., Peng, X. and Young, M.J.
Biotechnology Advances 36 (8): 2077-2100. December 2018

Targeting the intrinsically disordered proteome using small-molecule ligands.
Wójcik, S., Birol, M., Rhoades, E., Miranker, A.D. and Levine, Z.A.
Methods in Enzymology 611 : 703-734. 2018

Perivascular fibrosis and the microvasculature of the heart. still hidden secrets of pathophysiology?
Ytrehus, K., Hulot, J.S., Perrino, Cinzia, Schiattarella, G.G. and Madonna, R.
Vascular Pharmacology 107 : 78-83. August 2018

Pluripotent stem cells for uncovering the role of mitochondria in human brain function and dysfunction.
Zink, A., Priller, J. and Prigione, A.
Journal of Molecular Biology 430 (7): 891-903. 30 March 2018

Human pulmonary 3D models for translational research.
Zscheppang, K., Berg, J., Hedtrich, S., Verheyen, L., Wagner, D.E., Suttorp, N., Hippenstiel, S. and Hocke, A.C.
Biotechnology Journal 13 (1): 1700341. January 2018

Weiterbildung und Zertifizierung in kardiovaskulärer Magnetresonanztomographie in Deutschland - Update 2018 [Training and certification in cardiovascular magnetic resonance imaging in Germany - update 2018].
von Knobelsdorff, F., Müllerleile, K., Friedrich, M. G., Rolf, A., Schulz-Menger, J., Katus, H. and Eitel, I.
Kardiologe 12 (3): 209-214. June 2018

Letter

A comparative analysis of human bone marrow-resident and peripheral memory B cells.
Becker, S.C., Szyska, M., Mensen, A., Hellwig, K., Otto, R., Olfe, L., Volk, H.D., Dörner, T., Dörken, B., Scheibenbogen, C., Schröder, J., Hocke, A.C. and Na, I.K.
Journal of Allergy and Clinical Immunology 141 (5): 1911-1913. May 2018

Gadolinium deposition in the brain after contrast-enhanced MRI: are the data valid?
Boyken, J., Niendorf, T., Flemming, B. and Seeliger, E.
Radiology 288 (2): 630-632. 19 June 2018

Interpretation of functional renal MRI findings : where physiology and imaging sciences need to talk across domains.
Brix, S., Cantow, K., Flemming, B., Pohlmann, A., Niendorf, T. and Seeliger, E.
Journal of Magnetic Resonance Imaging 47 (4): 1140-1141. April 2018

Intestinal electrolyte and fluid secretion: a model in trouble?
Cid, L.P., Jentsch, T.J. and Sepúlveda, F.V.
Journal of Physiology 596 (12): 2465-2466. 15 June 2018

Randomized, phase 3 trial of inotuzumab ozogamicin plus rituximab versus chemotherapy plus rituximab for relapsed/refractory aggressive B-cell non-Hodgkin lymphoma.
Dang, N.H., Ogura, M., Castaigne, S., Fayad, L.E., Jerkeman, M., Radford, J., Pezzutto, A., Bondarenko, I., Stewart, D.A., Shnaidman, M., Sullivan, S., Vandendries, E., Tobinai, K., Ramchandren, R., Hamlin, P.A., Giné, E. and Ando, K.
British Journal of Haematology 182 (4): 583-586. August 2018

A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire.
Dobeš, J., Edenhofer, F., Vobořil, M., Brabec, T., Dobešová, M., Čepková, A., Klein, L., Rajewsky, K. and Filipp, D.
European Journal of Immunology 48 (3): 546-548. March 2018

SMARCAD1 haploinsufficiency underlies Huriez syndrome and associated skin cancer susceptibility.
Günther, C., Lee-Kirsch, M.A., Eckhard, J., Matanovic, A., Kerscher, T., Rüschendorf, F., Klein, B., Berndt, N., Zimmermann, N., Flachmeier, C., Thuß, T., Lucas, N., Marenholz, I., Esparza-Gordillo, J., Hübner, N., Traupe, H., Delaporte, E. and Lee, Y.A.
Journal of Investigative Dermatology 138 (6): 1428-1431. June 2018

Faecal microbiota composition associates with abdominal pain in the general population.
Hadizadeh, F., Bonfiglio, F., Belheouane, M., Vallier, M., Sauer, S., Bang, C., Bujanda, L., Andreasson, A., Agreus, L., Engstrand, L., Talley, N.J., Rafter, J., Baines, J.F., Walter, S., Franke, A. and D'Amato, M.
Gut 67 (4): 778-779. 8 March 2018

Coinheritance of biallelic SLURP1 and SLC39A4 mutations cause a severe genodermatosis with skin peeling and hair loss all over the body.
Harms, F.L., Nampoothiri, S., Kortüm, F., Thomas, J., Panicker, V.V., Alawi, M., Altmüller, J., Yesodharan, D. and Kutsche, K.
British Journal of Dermatology 179 (5): 1192-1194. 1 November 2018

Letter to the Editor: Influence of rTMS on smoking in patients with schizophrenia.
Kamp, D., Engelke, C., Wobrock, T., Kunze, B., Wölwer, W., Winterer, G., Schmidt-Kraepelin, C., Gaebel, W., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Raees, A., Honer, W.G., Malchow, B., Schneider-Axmann, T., Falkai, P., Hasan, A. and Cordes, J.
Schizophrenia Research 192 : 481-484. February 2018

Neuro-Behcet's disease in a patient with thrombotic thrombocytopenic purpura.
Karaivanov, S., Krueger, A., Bethke, N., Radbruch, H., Eckardt, K.U. and Schreiber, A.
Rheumatology 57 (6): 1117-1118. 1 June 2018

Evaluation of food allergy candidate loci in the Genetics of Food Allergy Study.
Marenholz, I., Grosche, S., Rüschendorf, F., Kalb, B., Blumchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Yürek, S., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hubner, N., Niggemann, B., Beyer, K. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 142 (4): 1368-1370. October 2018

Teenage exercise is associated with earlier symptom onset in dysferlinopathy: a retrospective cohort study.
Moore, U.R., Jacobs, M., Fernandez-Torron, R., Jang, J., James, M.K., Mayhew, A., Rufibach, L., Mittal, P., Eagle, M., Cnaan, A., Carlier, P.G., Blamire, A., Hilsden, H., Lochmüller, H., Grieben, U., Spuler, S., Tesi Rocha, C., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Harms, M., Pestronk, A., Krause, S., Schreiber-Katz, O., Walter, M.C., Paradas, C., Hogrel, J.Y., Stojkovic, T., Takeda, S., Mori-Yoshimura, M., Bravver, E., Sparks, S., Diaz-Manera, J., Bello, L., Semplicini, C., Pegoraro, E., Mendell, J.R., Bushby, K. and Straub, V.
Journal of Neurology Neurosurgery and Psychiatry 89 (11): 1224-1226. November 2018

Retinal optical coherence tomography shows optic disc changes in low intracranial pressure headaches: a case report.
Oertel, F.C., Bosello, F. and Petzold, A.
Acta Neurologica Belgica 118 (1): 131-133. March 2018

Functional implications of novel ADAM10 mutations in reticulate acropigmentation of Kitamura.
Ralser, D.J., Lestringant, G.G., Du-Thanh, A., Kokordelis, P., Fischer, J., Basmanav, F.B.Ü., Wolf, S., Thiele, H., Altmüller, J., Nürnberg, P., Oji, V., Fritz, G., Frank, J. and Betz, R.C.
British Journal of Dermatology 177 (6): e340-e343. 8 January 2018

Chromothripsis is linked to alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype.
Rücker, F.G., Dolnik, A., Blätte, T.J., Teleanu, V., Ernst, A., Thol, F., Heuser, M., Ganser, A., Döhner, H., Döhner, K. and Bullinger, L.
Haematologica 103 (1): e17-e20. January 2018

Reduced-toxicity conditioning for allogeneic hematopoietic cell transplantation in elderly or comorbid patients with AML using fludarabine, BCNU and melphalan: disease stage at transplant determines outcome.
Wais, V., Kündgen, L., Bohl, S.R., von Harsdorf, S., Schlenk, R.F., Döhner, K., Teleanu, V., Bullinger, L., Nguyen, T.M., Drognitz, K., Moulin, J.C., Binnenhei, M., Bentz, M., Döhner, H., Bunjes, D., Kuchenbauer, F. and Ringhoffer, M.
Bone marrow transplantation 53 (1): 94-96. January 2018

Senior-Løken syndrome with IQCB1 mutation in Taiwan.
Yu, P.H., Kuo, Y.R., Altmüller, J. and Hwang, D.Y.
Kaohsiung Journal of Medical Sciences 34 (10): 588-589. October 2018

Expression of CD274 (PD-L1) is associated with unfavourable recurrent mutations in AML.
Zajac, M., Zaleska, J., Dolnik, A., Bullinger, L. and Giannopoulos, K.
British Journal of Haematology 183 (5): 822-825. December 2018

Picky: a simple online PRM and SRM method designer for targeted proteomics.
Zauber, H., Kirchner, M. and Selbach, M.
Nature Methods 15 (3): 156-157. 28 February 2018

Editorial

A panoramic view on GPCRs: the 1st Berlin Symposium for Interdisciplinary GPCR research.
Bock, A. and Bermudez, M.
Naunyn-Schmiedeberg's Archives of Pharmacology 391 (7): 769-771. July 2018

Scientists on the Spot: Salt, the microbiome, and cardiovascular diseases.
Czesnikiewicz-Guzik, M. and Mueller, D.N.
Cardiovascular Research 114 (10): e72-e73. 1 August 2018

How has microbiology changed over the past 25 years?
Doolittle, W.F., Finlay, B.B., Fischetti, V.A., Kaufmann, S.H.E., Sasakawa, C. and Sattentau, Q.
Trends in Microbiology 26 (4): 246-250. April 2018

An intrinsic interferon program protects stem cells from viral infection.
Haas, S. and Trumpp, A.
Developmental Cell 44 (3): 279-280. 5 February 2018

Can we end the salt wars with a randomized clinical trial in a controlled environment?
Jones, D.W., Luft, F.C., Whelton, P.K., Alderman, M.H., Hall, J.E., Peterson, E.D., Califf, R.M. and McCarron, D.A.
Hypertension 72 (1): 10-11. July 2018

Diverging roads to the heart.
Kelly, R.G. and Sperling, S.R.
Science 359 (6380): 1098-1099. 9 March 2018

Redundant regulation.
Lacadie, S.A. and Ohler, U.
Nature Ecology & Evolution 2 (3): 418-419. March 2018

Top-NOTCH regulation of cardiac metabolism.
Lim, R. and Potente, M.
Circulation 137 (24): 2609-2612. 12 June 2018

Salt, blood pressure, and aldosterone in women and men.
Luft, F.C.
Hypertension 71 (6): 1026-1027. June 2018

Pushing preeclampsia back to pre-preeclampsia.
Luft, F.C. and Dechend, R.
Trends in Cardiovascular Medicine 28 (8): 514-515. November 2018

Pendred, pendrin, pseudohypoaldosteronism type II, and renal tubular acidosis.
Luft, F.C. and Wagner, C.A.
Kidney International 94 (3): 457-459. September 2018

Generation of human induced pluripotent stem cells (EURACi001-A, EURACi002-A, EURACi003-A) from peripheral blood mononuclear cells of three patients carrying mutations in the CAV3 gene.
Meraviglia, V., Benzoni, P., Landi, S., Murano, C., Langione, M., Motta, B.M., Baratto, S., Silipigni, R., Di Segni, M., Pramstaller, P.P., DiFrancesco, D., Gazzerro, E., Barbuti, A. and Rossini, A.
Stem Cell Research 27 : 25-29. March 2018

Worldwide prevalence of neuromyelitis optica spectrum disorders.
Mori, M., Kuwabara, S. and Paul, F.
Journal of Neurology Neurosurgery and Psychiatry 89 (6): 555-556. June 2018

Venoplasty in MS: therapeutic intervention without any evidence.
Paul, F. and Wattjes, M.P.
Neurology 91 (18): 815-816. 30 October 2018

VZV-associated acute retinal necrosis in a patient with MS treated with natalizumab.
Pawlitzki, M., Teuber, J., Campe, C., Wagner, M., Schuart, C., Paul, F. and Bittner, D.
Neurology Neuroimmunology & Neuroinflammation 5 (5): e475. 1 September 2018

FACS single cell index sorting is highly reliable and determines immune phenotypes of clonally expanded T cells.
Penter, L., Dietze, K., Bullinger, L., Westermann, J., Rahn, H.P. and Hansmann, L.
European Journal of Immunology 48 (7): 1248-1250. July 2018

Extracellular signal-regulated kinase (ERK) in left ventricular pathological hypertrophy: not a new kid on the block anymore.
Schiattarella, G.G.
International Journal of Cardiology 271 : 260-261. 15 November 2018

Epigenetic control of lipid metabolism: implications for lifespan and healthspan.
Schiattarella, G.G. and Hill, J.A.
Cardiovascular Research 114 (6): e33-e35. 1 May 2018

Ventricular phenotyping reviews.
Schiattarella, G.G., Tong, D. and Hill, J.A.
Circulation 138 (8): 749-750. 21 August 2018

UnSASPing senescence: unmasking tumor suppression?
Schmitt, C.A.
Cancer Cell 34 (1): 6-8. 9 July 2018

Editorial overview.
Shvartsman, S. and Zinzen, R.
Current Opinion in Systems Biology 11 : v. October 2018

Preeclampsia: What does the brain tell us? Can we blame the eclampsia risk on a malperfused placenta?
Staff, A.C. and Dechend, R.
Hypertension 72 (1): 65-67. July 2018

Renin-angiotensin system in aortic aneurysm: still adding puzzle stones to an anything but complete picture.
Steckelings, U.M. and Bader, M.
Hypertension 72 (3): 579-581. September 2018

Verirrte Proteine lösen Erbkrankheiten aus [Lost proteins trigger hereditary diseases].
Tuffs, A.
Medizinische Genetik 30 (3): 350. November 2018

Editorial: Perivascular adipose tissue (PVAT) in health and disease.
Watts, S.W. and Gollasch, M.
Frontiers in Physiology 9 : 1004. July 2018

Good things come in threes.
Yona, S. and Mildner, A.
Science Immunology 3 (30): eaav5545. 7 December 2018

Comment

Studies of the bugs within: telling sickness from cure.
Forslund, S.K. and Pedersen, O.
TheScienceBreaker 4 (1) 20 March 2018

Preprint

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types.
Calabrese, C., Davidson, N.R., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., Soulette, C.M., Urban, L., Demircioğlu, D., Greger, L., Li, S., Liu, D., Perry, M.D., Xiang, L., Zhang, F., Zhang, J., Bailey, P., Erkek, S., Hoadley, K.A., Hou, Y., Kilpinen, H., Korbel, J.O., Marin, M.G., Markowski, J., Nandi, T., Pan-Hammarström, Q., Pedamallu, C.S., Siebert, R., Stark, S.G., Su, H., Tan, P., Waszak, S.M., Yung, C., Zhu, S., Awadalla, P., Creighton, C.J., Meyerson, M., Ouellette, B.F.F., Wu, K., Yang, H., Brazma, A., Brooks, A.N., Göke, J., Rätsch, G., Schwarz, R.F., Stegle, O. and Zhang, Z.
bioRxiv : 183889. 12 March 2018

Glutamate uptake and release at single adult corticostriatal synapses of normal and Huntington mice.
Dvorzhak, A., Helassa, N., Torok, K., Schmitz, D. and Grantyn, R.
bioRxiv : 455758. 30 October 2018

An eicosanoid protects from statin-induced myopathic changes in primary human cells.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
bioRxiv : 271932. 26 February 2018

Mutant Plasticity Related Gene 1 (PRG1) acts as a potential modifier in SCN1A related epilepsy.
Knierim, E., Vogt, J., Kintscher, M., Ponomarenko, A., Baumgart, J., Sanker Beed, P., Korotkova, T., Trimbuch, T., Panzer, A., Stephani, U., Escayg, A., Lerche, H., Nitsch, R., Schmitz, D. and Schuelke, M.
bioRxiv : 282871. 15 March 2018

Mutant screen reveals the Piccolo's control over depression and brain-gonad crosstalk.
Medrano, G.A., Singh, M., Plautz, E.J., Good, L.B., Chapman, K.M., Chaudhary, J., Jaichander, P., Powell, H.M., Pudasaini, A., Shelton, J.M., Richardson, J.A., Xie, X.J., Ivics, Z., Braun, C., Ackermann, F., Garner, C.C., Izsvak, Z. and Hamra, F.K.
bioRxiv : 405985. 31 August 2018

Emergence of robust nucleosome patterns from an interplay of positioning mechanisms.
Nuebler, J., Wolff, M., Obermayer, B., Mobius, W. and Gerland, U.
bioRxiv : 431445. 1 October 2018

Quantifying multi-layered expression regulation in response to stress of the endoplasmic reticulum.
Rendleman, J., Cheng, Z., Maity, S., Kastelic, N., Munschauer, M., Allgoewer, K., Teo, G., Zhang, Y.B., Lei, A., Parker, B., Landthaler, M., Freeberg, L., Kuersten, S., Choi, H. and Vogel, C.
bioRxiv : 308379. 25 April 2018

Non-canonical HIF-1 stabilization is essential for intestinal tumorigenesis.
Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K.T., Fragoulis, A., Kuehl, A.A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C.E., Brenner, W., Malinowski, M.B., Stockmann, M., Schomburg, L., Faller, W., Sansom, O.J., Tacke, F., Morkel, M. and Cramer, T.
bioRxiv : 273045. 28 February 2018

The phylogenetically distinct early human embryo.
Singh, M., Widmann, T.J., Cortes, J.L., Schumann, G.G., Wunderlich, S., Martin, U., Garcia-Perez, J.L., Hurst, L.D. and Izsvak, Z.
bioRxiv : 318329. 18 May 2018

Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury.
Van Steenwinckel, J., Schang, A.L., Krishnan, M.L., Degos, V., Delahaye-Duriez, A., Bokobza, C., Verdonk, F., Montane, A., Sigaut, S., Hennebert, O., Lebon, S., Schwendimann, L., Le Charpentier, T., Hassan-Abdi, R., Ball, G., Aljabar, P., Saxena, A., Holloway, R.K., Birchmeier, W., Miron, V., Rowitch, D., Chretien, F., Leconte, C., Besson, V.C., Petretto, E.G., Edwards, A.D., Hagberg, H., Soussi-Yanicostas, N., Fleiss, B. and Gressens, P.
bioRxiv : 334359. 31 May 2018

Cumulative regulatory potential of clustered methyl-arginine protein modifications.
Woodsmith, J., Casado-Medrano, V., Benlasfer, N., Eccles, R.L., Hutten, S., Heine, C., Thormann, V., Abou-Ajram, C., Rocks, O., Dormann, D. and Stelzl, U.
bioRxiv : 289041. 26 March 2018

This list was generated on Thu Oct 3 14:30:30 2024 UTC.
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