Items where Year is 2018

A

A mechanistic classification of clinical phenotypes in neuroblastoma.
Ackermann, S., Cartolano, M., Hero, B., Welte, A., Kahlert, Y., Roderwieser, A., Bartenhagen, C., Walter, E., Gecht, J., Kerschke, L., Volland, R., Menon, R., Heuckmann, J.M., Gartlgruber, M., Hartlieb, S., Henrich, K.O., Okonechnikov, K., Altmüller, J., Nürnberg, P., Lefever, S., de Wilde, B., Sand, F., Ikram, F., Rosswog, C., Fischer, J., Theissen, J., Hertwig, F., Singhi, A.D., Simon, T., Vogel, W., Perner, S., Krug, B., Schmidt, M., Rahmann, S., Achter, V., Lang, U., Vokuhl, C., Ortmann, M., Büttner, R., Eggert, A., Speleman, F., O'Sullivan, R.J., Thomas, R.K., Berthold, F., Vandesompele, J., Schramm, A., Westermann, F., Schulte, J.H., Peifer, M. and Fischer, M.
Science 362 (6419): 1165-1170. 7 December 2018

Addressing the perfect storm: biomarkers in obesity and pathophysiology of cardiometabolic risk.
Aleksandrova, K., Mozaffarian, D. and Pischon, T.
Clinical Chemistry 64 (1): 142-153. January 2018

The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.
Althof, N., Goetzke, C.C., Kespohl, M., Voss, K., Heuser, A., Pinkert, S., Kaya, Z., Klingel, K. and Beling, A.
EMBO Molecular Medicine 10 (2): 200-218. 1 February 2018

Polarity acquisition in cortical neurons is driven by synergistic action of Sox9-regulated Wwp1 and Wwp2 E3 ubiquitin ligases and intronic miR-140.
Ambrozkiewicz, M.C., Schwark, M., Kishimoto-Suga, M., Borisova, E., Hori, K., Salazar-Lázaro, A., Rusanova, A., Altas, B., Piepkorn, L., Bessa, P., Schaub, T., Zhang, X., Rabe, T., Ripamonti, S., Rosário, M., Akiyama, H., Jahn, O., Kobayashi, T., Hoshino, M., Tarabykin, V. and Kawabe, H.
Neuron 100 (5): 1097-1115. 5 December 2018

Related GPCRs couple differently to G(s): preassociation between G protein and 5-HT(7) serotonin receptor reveals movement of Gα(s) upon receptor activation.
Andressen, K.W., Ulsund, A.H., Krobert, K.A., Lohse, M.J., Buenemann, M. and Levy, F.O.
FASEB Journal 32 (2): 1059-1069. 5 February 2018

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Angulo-Urarte, A., Casado, P., Castillo, S.D., Kobialka, P., Kotini, M.P., Figueiredo, A.M., Castel, P., Rajeeve, V., Milà-Guasch, M., Millan, J., Wiesner, C., Serra, H., Muixi, L., Casanovas, O., Viñals, F., Affolter, M., Gerhardt, H., Huveneers, S., Belting, H.G., Cutillas, P.R. and Graupera, M.
Nature Communications 9 (1): 4826. 16 November 2018

Molecular Dynamics simulations of the Strings and Binders Switch Model of chromatin.
Annunziatella, C., Chiariello, A.M., Esposito, A., Bianco, S., Fiorillo, L. and Nicodemi, M.
Methods 142 : 81-88. 1 June 2018

Proteomics, post-translational modifications, and integrative analyses reveal molecular heterogeneity within medulloblastoma subgroups.
Archer, T.C., Ehrenberger, T., Mundt, F., Gold, M.P., Krug, K., Mah, C.K., Mahoney, E.L., Daniel, C.J., LeNail, A., Ramamoorthy, D., Mertins, P., Mani, D.R., Zhang, H., Gillette, M.A., Clauser, K., Noble, M., Tang, L.C., Pierre-François, J., Silterra, J., Jensen, J., Tamayo, P., Korshunov, A., Pfister, S.M., Kool, M., Northcott, P.A., Sears, R.C., Lipton, J.O., Carr, S.A., Mesirov, J.P., Pomeroy, S.L. and Fraenkel, E.
Cancer Cell 34 (3): 396-410. 10 September 2018

Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.
Arends, C.M., Galan-Sousa, J., Hoyer, K., Chan, W., Jäger, M., Yoshida, K., Seemann, R., Noerenberg, D., Waldhueter, N., Fleischer-Notter, H., Christen, F., Schmitt, C.A., Dörken, B., Pelzer, U., Sinn, M., Zemojtel, T., Ogawa, S., Märdian, S., Schreiber, A., Kunitz, A., Krüger, U., Bullinger, L., Mylonas, E., Frick, M. and Damm, F.
Leukemia 32 (9): 1908-1919. September 2018

Allosteric inhibition of a mammalian lectin.
Aretz, J., Anumala, U.R., Fuchsberger, F.F., Molavi, N., Ziebart, N., Zhang, H., Nazaré, M. and Rademacher, C.
Journal of the American Chemical Society 140 (44): 14915-14925. 7 November 2018

SETD1A protects HSCs from activation-induced functional decline in vivo.
Arndt, K., Kranz, A., Fohgrub, J., Jolly, A., Bledau, A.S., Di Virgilio, M., Lesche, M., Dahl, A., Höfer, T., Stewart, A.F. and Waskow, C.
Blood 131 (12): 1311-1324. 22 March 2018

Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.
Arnhold, V., Schmelz, K., Proba, J., Winkler, A., Wünschel, J., Toedling, J., Deubzer, H.E., Künkele, A., Eggert, A., Schulte, J.H. and Hundsdoerfer, P.
Oncotarget 9 (2): 2304-2319. 2018

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.
Arnoux, I., Willam, M., Griesche, N., Krummeich, J., Watari, H., Offermann, N., Weber, S., Narayan Dey, P., Chen, C., Monteiro, O., Buettner, S., Meyer, K., Bano, D., Radyushkin, K., Langston, R., Lambert, J.J., Wanker, E., Methner, A., Krauss, S., Schweiger, S. and Stroh, A.
eLife 7 : e38744. 4 September 2018

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.
Asai, Y., Eslami, A., van Ginkel, C.D., Akhabir, L., Wan, M., Yin, D., Ellis, G., Ben-Shoshan, M., Marenholz, I., Martino, D., Ferreira, M.A., Allen, K., Mazer, B., de Groot, H., de Jong, N.W., Gerth van Wijk, R., Dubois, A.E.J., Grosche, S., Ashley, S., Rüschendorf, F., Kalb, B., Beyer, K., Nöthen, M.M., Lee, Y.A., Chin, R., Cheuk, S., Hoffman, J., Jorgensen, E., Witte, J.S., Melles, R.B., Hong, X., Wang, X., Hui, J., Musk, A.W.B., Hunter, M., James, A.L., Koppelman, G.H., Sandford, A.J., Clarke, A.E. and Daley, D.
Journal of Allergy and Clinical Immunology 141 (4): 1513-1516. April 2018

Candidate gene testing in clinical cohort studies with multiplexed genotyping and mass spectrometry.
Ashley, S.E., Meyer, B.A., Ellis, J.A. and Martino, D.J.
Journal of Visualized Experiments (136): e57601. 21 June 2018

Pain in AQP4-IgG-positive and MOG-IgG-positive neuromyelitis optica spectrum disorders.
Asseyer, S., Schmidt, F., Chien, C., Scheel, M., Ruprecht, K., Bellmann-Strobl, J., Brandt, A.U. and Paul, F.
Multiple Sclerosis Journal Experimental Translational and Clinical 4 (3): 2055217318796684. 1 July 2018

mHTT seeding activity: a marker of disease progression and neurotoxicity in models of Huntington's disease.
Ast, A., Buntru, A., Schindler, F., Hasenkopf, R., Schulz, A., Brusendorf, L., Klockmeier, K., Grelle, G., McMahon, B., Niederlechner, H., Jansen, I., Diez, L., Edel, J., Boeddrich, A., Franklin, S.A., Baldo, B., Schnoegl, S., Kunz, S., Purfürst, B., Gaertner, A., Kampinga, H.H., Morton, A.J., Petersén, Å., Kirstein, J., Bates, G.P. and Wanker, E.E.
Molecular Cell 71 (5): 675-688. 6 September 2018

A filter retardation assay facilitates the detection and quantification of heat-stable, amyloidogenic mutant huntingtin aggregates in complex biosamples.
Ast, A., Schindler, F., Buntru, A., Schnoegl, S. and Wanker, E.E.
Methods in Molecular Biology 1780 : 31-40. 2018

Temporal visual resolution and disease severity in MS.
Ayadi, N., Dörr, J., Motamedi, S., Gawlik, K., Bellmann-Strobl, J., Mikolajczak, J., Brandt, A.U., Zimmermann, H. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 5 (5): e492. 1 September 2018

B

Anatomical wiring and functional networking changes in the visual system following optic neuritis.
Backner, Y., Kuchling, J., Massarwa, S., Oberwahrenbrock, T., Finke, C., Bellmann-Strobl, J., Ruprecht, K., Brandt, A.U., Zimmermann, H., Raz, N., Paul, F. and Levin, N.
JAMA Neurology 75 (3): 287-295. March 2018

The Meaning of Mas.
Bader, M., Alenina, N., Young, D., Santos, R.A.S. and Touyz, R.M.
Hypertension 72 (5): 1072-1075. November 2018

Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same.
Max-Delbrück-Centrum für Molekulare Medizin.
201615552556. 22 February 2018

Newly designed 16S rRNA metabarcoding primers amplify diverse and novel archaeal taxa from the environment.
Bahram, M., Anslan, S., Hildebrand, F., Bork, P. and Tedersoo, L.
Environmental Microbiology Reports 11 (4): 487-494. August 2018

Structure and function of the global topsoil microbiome.
Bahram, M., Hildebrand, F., Forslund, S.K., Anderson, J.L., Soudzilovskaia, N.A., Bodegom, P.M., Bengtsson-Palme, J., Anslan, S., Coelho, L.P., Harend, H., Huerta-Cepas, J., Medema, M.H., Maltz, M.R., Mundra, S., Olsson, P.A., Pent, M., Põlme, S., Sunagawa, S., Ryberg, M., Tedersoo, L. and Bork, P.
Nature 560 (7717): 233-237. 9 August 2018

The International Multiple Sclerosis Visual System Consortium: advancing visual system research in multiple sclerosis.
Balcer, L.J., Balk, L.J., Brandt, A.U., Calabresi, P.A., Martinez-Lapiscina, E.H., Nolan, R.C., Paul, F., Petzold, A. and Saidha, S.
Journal of Neuro-Ophthalmology 38 (4): 494-501. December 2018

ProTox-II: a webserver for the prediction of toxicity of chemicals.
Banerjee, P., Eckert, A.O., Schrey, A.K. and Preissner, R.
Nucleic Acids Research 46 (W1): W257-W263. 2 July 2018

BitterSweetForest: a Random Forest based binary classifier to predict bitterness and sweetness of chemical compounds.
Banerjee, P. and Preissner, R.
Frontiers in Chemistry 6 : 93. April 2018

Role of VTA dopamine neurons and neuroligin 3 in sociability traits related to nonfamiliar conspecific interaction.
Bariselli, S., Hörnberg, H., Prévost-Solié, C., Musardo, S., Hatstatt-Burklé, L., Scheiffele, P. and Bellone, C.
Nature Communications 9 (1): 3173. 9 August 2018

Chronic overexpression of bradykinin in kidney causes polyuria and cardiac hypertrophy.
Barros, C.C., Schadock, I., Sihn, G., Rother, F., Xu, P., Popova, E., Lapidus, I., Plehm, R., Heuser, A., Todiras, M., Bachmann, S., Alenina, N., Araujo, R.C., Pesquero, J.B. and Bader, M.
Frontiers in Medicine 5 : 338. December 2018

All-optical microscope autofocus based on an electrically tunable lens and a totally internally reflected IR laser.
Bathe-Peters, M., Annibale, P. and Lohse, M.J.
Optics Express 26 (3): 2359-2368. 5 February 2018

Pervasive protein thermal stability variation during the cell cycle.
Becher, I., Andrés-Pons, A., Romanov, N., Stein, F., Schramm, M., Baudin, F., Helm, D., Kurzawa, N., Mateus, A., Mackmull, M.T., Typas, A., Müller, C.W., Bork, P., Beck, M. and Savitski, M.M.
Cell 173 (6): 1495-1507. 31 May 2018

In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI.
Becker, K.M., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Current Directions in Biomedical Engineering 4 (1): 263-266. 1 September 2018

A comparative analysis of human bone marrow-resident and peripheral memory B cells.
Becker, S.C., Szyska, M., Mensen, A., Hellwig, K., Otto, R., Olfe, L., Volk, H.D., Dörner, T., Dörken, B., Scheibenbogen, C., Schröder, J., Hocke, A.C. and Na, I.K.
Journal of Allergy and Clinical Immunology 141 (5): 1911-1913. May 2018

7 Tesla MRI of Balo's concentric sclerosis versus multiple sclerosis lesions.
Behrens, J.R., Wanner, J., Kuchling, J., Ostendorf, L., Harms, L., Ruprecht, K., Niendorf, T., Jarius, S., Wildemann, B., Gieß, R.M., Scheel, M., Bellmann-Strobl, J., Wuerfel, J., Paul, F. and Sinnecker, T.
Annals of Clinical and Translational Neurology 5 (8): 900-912. August 2018

Novel strategy for the preparation of 3-perfluoroalkylated-2 H-indazole derivatives.
Bel Abed, H., Weißing, N., Schoene, J., Paulus, J., Sewald, N. and Nazaré, M.
Tetrahedron Letters 59 (19): 1813-1815. 9 May 2018

CCR7 on CD4(+) T cells plays a crucial role in the induction of experimental autoimmune encephalomyelitis.
Belikan, P., Bühler, U., Wolf, C., Pramanik, G.K., Gollan, R., Zipp, F. and Siffrin, V.
Journal of Immunology 200 (8): 2554-2562. 15 April 2018

The effectiveness of acupuncture and mindfulness-based stress reduction (MBSR) for patients with multiple sclerosis associated fatigue: a study protocol and its rationale for a randomized controlled trial.
Bellmann-Strobl, J., Pach, D., Chang, Y., Pasura, L., Liu, B., Jäger, S.F., Loerch, R., Jin, L., Blödt, S., Brinkhaus, B., Ortiz, M., Reinhold, T., Roll, S., Binting, S., Paul, F., Witt, C.M. and Shi, X.
European Journal of Integrative Medicine 20 : 6-15. June 2018

CRISPR correction of the PRKAG2 gene mutation in the patient's iPSC-derived cardiomyocytes eliminates the electrophysiological and structural abnormalities.
Ben Jehuda, R., Eisen, B., Shemer, Y., Mekies, L.N., Szantai, A., Reiter, I., Cui, H., Guan, K., Haron-Khun, S., Freimark, D., Sperling, S.R., Gherghiceanu, M., Arad, M. and Binah, O.
Heart Rhythm 15 (2): 267-276. February 2018

Information flow in a mammalian signal transduction pathway.
Benary, M., Nolis, I., Blüthgen, N. and Loewer, A.
In: Information- and Communication Theory in Molecular Biology. Lecture Notes in Bioengineering . Springer, Cham, Switzerland, 101-114. ISBN 978-3-319-54728-2 2018

The c-Myc/miR17-92/PTEN axis tunes PI3K activity to control expression of recombination activating genes in early B cell development.
Benhamou, D., Labi, V., Getahun, A., Benchetrit, E., Dowery, R., Rajewsky, K., Cambier, J.C. and Melamed, D.
Frontiers in Immunology 9 : 2715. November 2018

Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues.
Benndorf, R., Gilmont, R.R., Hirano, S., Ransom, R.F., Jungblut, P.R., Bommer, M., Goldman, J.E. and Welsh, M.J.
Cell Stress & Chaperones 23 (5): 813-826. September 2018

Deletion of protein kinase D1 in pancreatic β-cells impairs insulin secretion in high-fat diet-fed mice.
Bergeron, V., Ghislain, J., Vivot, K., Tamarina, N., Philipson, L.H., Fielitz, J. and Poitout, V.
Diabetes 67 (1): 71-77. January 2018

PolNet: a tool to quantify network-level cell polarity and blood flow in vascular remodeling.
Bernabeu, M.O., Jones, M.L., Nash, R.W., Pezzarossa, A., Coveney, P.V., Gerhardt, H. and Franco, C.A.
Biophysical Journal 114 (9): 2052-2058. 8 May 2018

Potassium channel-based optogenetic silencing.
Bernal Sierra, Y.A., Rost, B.R., Pofahl, M., Fernandes, A.M., Kopton, R.A., Moser, S., Holtkamp, D., Masala, N., Beed, P., Tukker, J.J., Oldani, S., Bönigk, W., Kohl, P., Baier, H., Schneider-Warme, F., Hegemann, P., Beck, H., Seifert, R. and Schmitz, D.
Nature Communications 9 (1): 4611. 5 November 2018

Understanding chromatin structure: efficient computational implementation of polymer physics models.
Bianco, S., Annunziatella, C., Esposito, A., Fiorillo, L., Conte, M., Campanile, R. and Chiariello, A.M.
Lecture Notes in Computer Science 11339 : 680-691. 2018

Polymer physics predicts the effects of structural variants on chromatin architecture.
Bianco, S., Lupiáñez, D.G., Chiariello, A.M., Annunziatella, C., Kraft, K., Schöpflin, R., Wittler, L., Andrey, G., Vingron, M., Pombo, A., Mundlos, S. and Nicodemi, M.
Nature Genetics 50 (5): 662-667. May 2018

Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid.
Birol, M., Kumar, S., Rhoades, E. and Miranker, A.D.
Nature Communications 9 (1): 1312. 3 April 2018

Omics-based approach reveals complement-mediated inflammation in chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).
Blaabjerg, M., Hemdrup, A.L., Drici, L., Ruprecht, K., Garred, P., Höftberger, R., Kristensen, B.W., Kondziella, D., Sejbaek, T., Hansen, S.W., Nielsen, H.H., Jensen, P., Meyer, M., Paul, F., Lassmann, H., Larsen, M.R. and Illes, Z.
Frontiers in Immunology 9 : 741. 23 April 2018

CAR T cells with enhanced sensitivity to B cell maturation antigen for the targeting of B cell non-Hodgkin's lymphoma and multiple myeloma.
Bluhm, J., Kieback, E., Marino, S.F., Oden, F., Westermann, J., Chmielewski, M., Abken, H., Uckert, W., Höpken, U.E. and Rehm, A.
Molecular Therapy 26 (8): 1906-1920. 1 August 2018

Exome-wide analysis of mutational burden in patients with typical and atypical Rolandic epilepsy.
Bobbili, D.R., Lal, D., May, P., Reinthaler, E.M., Jabbari, K., Thiele, H., Nothnagel, M., Jurkowski, W., Feucht, M., Nürnberg, P., Lerche, H., Zimprich, F., Krause, R., Neubauer, B.A., Reinthaler, E.M., Zimprich, F., Feucht, M., Steinböck, H., Neophytou, B., Geldner, J., Gruber-Sedlmayr, U., Haberlandt, E., Ronen, G.M., Altmüller, J., Lal, D., Nürnberg, P., Sander, T., Thiele, H., Krause, R., May, P., Balling, R., Lerche, H. and Neubauer, B.A.
European Journal of Human Genetics 26 (2): 258-264. February 2018

A panoramic view on GPCRs: the 1st Berlin Symposium for Interdisciplinary GPCR research.
Bock, A. and Bermudez, M.
Naunyn-Schmiedeberg's Archives of Pharmacology 391 (7): 769-771. July 2018

Allosteric modulators targeting CNS muscarinic receptors.
Bock, A., Schrage, R. and Mohr, K.
Neuropharmacology 136 (Part C): 427-437. 1 July 2018

Ketogenic diets attenuate cyclooxygenase and lipoxygenase gene expression in multiple sclerosis.
Bock, M., Karber, M. and Kuhn, H.
EBioMedicine 36 : 293-303. October 2018

Exon junction complexes suppress spurious splice sites to safeguard transcriptome integrity.
Boehm, V., Britto-Borges, T., Steckelberg, A.L., Singh, K.K., Gerbracht, J.V., Gueney, E., Blazquez, L., Altmüller, J., Dieterich, C. and Gehring, N.H.
Molecular Cell 72 (3): 482-495. 1 November 2018

Epigenetic therapy: azacytidine and decitabine in acute myeloid leukemia.
Bohl, S.R., Bullinger, L. and Rücker, F.G.
Expert Review of Hematology 11 (5): 361-371. May 2018

Somatostatin 2 receptor activation in the rostral ventrolateral medulla does not mediate the decompensatory phase of haemorrhage.
Bokiniec, P., Burke, P.G.R., Turner, A.J., McMullan, S. and Goodchild, A.K.
Shock 50 (3): 331-338. September 2018

The neural circuits of thermal perception.
Bokiniec, P., Zampieri, N., Lewin, G.R. and Poulet, J.F.A.
Current Opinion in Neurobiology 52 : 98-106. October 2018

Possible role of CYP450 generated omega-3/omega-6 PUFA metabolites in the modulation of blood pressure and vascular function in obese children.
Bonafini, S., Giontella, A., Tagetti, A., Marcon, D., Montagnana, M., Benati, M., Gaudino, R., Cavarzere, P., Karber, M., Rothe, M., Minuz, P., Antonazzi, F., Maffeis, C., Schunck, W.H. and Fava, C.
Nutrients 10 (11): 1689. 5 November 2018

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.
Bonnin, E., Cabochette, P., Filosa, A., Jühlen, R., Komatsuzaki, S., Hezwani, M., Dickmanns, A., Martinelli, V., Vermeersch, M., Supply, L., Martins, N., Pirenne, L., Ravenscroft, G., Lombard, M., Port, S., Spillner, C., Janssens, S., Roets, E., Van Dorpe, J., Lammens, M., Kehlenbach, R.H., Ficner, R., Laing, N.G., Hoffmann, K., Vanhollebeke, B. and Fahrenkrog, B.
PLoS Genetics 14 (12): e1007845. 13 December 2018

Neuromyelitis optica spectrum disorders and pregnancy: relapse-preventive measures and personalized treatment strategies.
Borisow, N., Hellwig, K. and Paul, F.
EPMA Journal 9 (3): 249-256. September 2018

Neuromyelitis-optica-Spektrum-Erkrankung und Schwangerschaft [Neuromyelitis optica spectrum disorder and pregnancy].
Borisow, N., Hellwig, K. and Paul, F.
Nervenarzt 89 (6): 666-673. June 2018

Diagnosis and treatment of NMO spectrum disorder and MOG-encephalomyelitis.
Borisow, N., Mori, M., Kuwabara, S., Scheel, M. and Paul, F.
Frontiers in Neurology 9 : 888. October 2018

Ten things you should know about transposable elements.
Bourque, G., Burns, K.H., Gehring, M., Gorbunova, V., Seluanov, A., Hammell, M., Imbeault, M., Izsvák, Z., Levin, H.L., Macfarlan, T.S., Mager, D.L. and Feschotte, C.
Genome Biology 19 (1): 199. 19 November 2018

Gadolinium deposition in the brain after contrast-enhanced MRI: are the data valid?
Boyken, J., Niendorf, T., Flemming, B. and Seeliger, E.
Radiology 288 (2): 630-632. 19 June 2018

ATP6AP2 over-expression causes morphological alterations in the hippocampus and in hippocampus-related behaviour.
Bracke, A., Schäfer, S., von Bohlen und Halbach, V., Klempin, F., Bente, K., Bracke, K., Staar, D., van den Brandt, J., Harzsch, S., Bader, M., Wenzel, U.O., Peters, J. and von Bohlen und Halbach, O.
Brain Structure & Function 223 (5): 2287-2302. June 2018

Frequent retinal ganglion cell damage after acute optic neuritis.
Brandt, A.U., Specovius, S., Oberwahrenbrock, T., Zimmermann, H.G., Paul, F. and Costello, F.
Multiple Sclerosis and Related Disorders 22 : 141-147. May 2018

Self-perception and determinants of color vision in Parkinson's disease.
Brandt, A.U., Zimmermann, H.G., Oberwahrenbrock, T., Isensee, J., Müller, T. and Paul, F.
Journal of Neural Transmission 125 (2): 145-152. February 2018

Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.
Braun, D.A., Lovric, S., Schapiro, D., Schneider, R., Marquez, J., Asif, M., Hussain, M.S., Daga, A., Widmeier, E., Rao, J., Ashraf, S., Tan, W., Lusk, C.P., Kolb, A., Jobst-Schwan, T., Schmidt, J.M., Hoogstraten, C.A., Eddy, K., Kitzler, T.M., Shril, S., Moawia, A., Schrage, K., Khayyat, A.I.A., Lawson, J.A., Gee, H.Y., Warejko, J.K., Hermle, T., Majmundar, A.J., Hugo, H., Budde, B., Motameny, S., Altmüller, J., Noegel, A. A., Fathy, H.M., Gale, D.P., Waseem, S.S., Khan, A., Kerecuk, L., Hashmi, S., Mohebbi, N., Ettenger, R., Serdaroğlu, E., Alhasan, K.A., Hashem, M., Goncalves, S., Ariceta, G., Ubetagoyena, M., Antonin, W., Baig, S.M., Alkuraya, F.S., Shen, Q., Xu, H., Antignac, C., Lifton, R.P., Mane, S., Nürnberg, P., Khokha, M.K. and Hildebrandt, F.
Journal of Clinical Investigation 128 (10): 4313-4328. 1 October 2018

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation.
Breglio, K.F., Amato, R., Eastman, R., Lim, P., Sa, J.M., Guha, R., Ganesan, S., Dorward, D.W., Klumpp-Thomas, C., McKnight, C., Fairhurst, R.M., Roberts, D., Thomas, C. and Simon, A.K.
Malaria Journal 17 (1): 391. 26 October 2018

Deletion of claudin-10 rescues claudin-16-deficient mice from hypomagnesemia and hypercalciuria.
Breiderhoff, T., Himmerkus, N., Drewell, H., Plain, A., Guenzel, D., Mutig, K., Willnow, T.E., Müller, D. and Bleich, M.
Kidney International 93 (3): 580-588. March 2018

Mechanisms of targeting the MDM2-p53-FOXM1 axis in well-differentiated intestinal neuroendocrine tumors.
Briest, F., Grass, I., Sedding, D., Moebs, M., Christen, F., Benecke, J., Fuchs, K., Mende, S., Kaemmerer, D., Saenger, J., Kunze, A., Geisler, C., Freitag, H., Lewens, F., Worpenberg, L., Iwaszkiewicz, S., Siegmund, B., Walther, W., Hummel, M. and Grabowski, P.
Neuroendocrinology 107 (1): 1-23. July 2018

TPH2 deficiency influences neuroplastic mechanisms and alters the response to an acute stress in a sex specific manner.
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Frontiers in Molecular Neuroscience 11 : 389. 30 October 2018

Interpretation of functional renal MRI findings : where physiology and imaging sciences need to talk across domains.
Brix, S., Cantow, K., Flemming, B., Pohlmann, A., Niendorf, T. and Seeliger, E.
Journal of Magnetic Resonance Imaging 47 (4): 1140-1141. April 2018

Species-specific activity of antibacterial drug combinations.
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Nature 559 (7713): 259-263. July 2018

Mutations in plasmalemma vesicle-associated protein cause severe syndromic protein-losing enteropathy.
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Journal of Medical Genetics 55 (9): 637-640. September 2018

Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial.
Burock, S., Daum, S., Keilholz, U., Neumann, K., Walther, W. and Stein, U.
BMC Cancer 18 (1): 297. 15 March 2018

The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse.
Bégay, V., Baumeier, C., Zimmermann, K., Heuser, A. and Leutz, A.
Scientific Reports 8 (1): 8417. 30 May 2018

Routes to, from and within the subiculum.
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GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis.
Cabral-Marques, O., Marques, A., Giil, L.M., De Vito, R., Rademacher, J., Günther, J., Lange, T., Humrich, J.Y., Klapa, S., Schinke, S., Schimke, L.F., Marschner, G., Pitann, S., Adler, S., Dechend, R., Müller, D.N., Braicu, I., Sehouli, J., Schulze-Forster, K., Trippel, T., Scheibenbogen, C., Staff, A., Mertens, P.R., Löbel, M., Mastroianni, J., Plattfaut, C., Gieseler, F., Dragun, D., Engelhardt, B.E., Fernandez-Cabezudo, M.J., Ochs, H.D., Al-Ramadi, B.K., Lamprecht, P., Mueller, A., Heidecke, H. and Riemekasten, G.
Nature Communications 9 (1): 5224. 6 December 2018

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types.
Calabrese, C., Davidson, N.R., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., Soulette, C.M., Urban, L., Demircioğlu, D., Greger, L., Li, S., Liu, D., Perry, M.D., Xiang, L., Zhang, F., Zhang, J., Bailey, P., Erkek, S., Hoadley, K.A., Hou, Y., Kilpinen, H., Korbel, J.O., Marin, M.G., Markowski, J., Nandi, T., Pan-Hammarström, Q., Pedamallu, C.S., Siebert, R., Stark, S.G., Su, H., Tan, P., Waszak, S.M., Yung, C., Zhu, S., Awadalla, P., Creighton, C.J., Meyerson, M., Ouellette, B.F.F., Wu, K., Yang, H., Brazma, A., Brooks, A.N., Göke, J., Rätsch, G., Schwarz, R.F., Stegle, O. and Zhang, Z.
bioRxiv : 183889. 12 March 2018

Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis.
Campa, C.C., Silva, R.L., Margaria, J.P., Pirali, T., Mattos, M.S., Kraemer, L.R., Reis, D.C., Grosa, G., Copperi, F., Dalmarco, E.M., Lima-Júnior, R.C.P., Aprile, S., Sala, V., Dal Bello, F., Prado, D.S., Alves-Filho, J.C., Medana, C., Cassali, G.D., Tron, G.C., Teixeira, M.M., Ciraolo, E., Russo, R.C. and Hirsch, E.
Nature Communications 9 (1): 5232. 12 December 2018

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.
Cantù, C., Felker, A., Zimmerli, D., Prummel, K.D., Cabello, E.M., Chiavacci, E., Méndez-Acevedo, K.M., Kirchgeorg, L., Burger, S., Ripoll, J., Valenta, T., Hausmann, G., Vilain, N., Aguet, M., Burger, A., Panáková, D., Basler, K. and Mosimann, C.
Genes & Development 32 (21-22): 1443-1458. 1 November 2018

Cytosolic DNA sensing promotes macrophage transformation and governs myocardial ischemic injury.
Cao, D.J., Schiattarella, G.G., Villalobos, E., Jiang, N., May, H.I., Li, T., Chen, Z.J., Gillette, T.G. and Hill, J.A.
Circulation 137 (24): 2613-2634. 12 June 2018

SPECT/MRI INSERT compatibility: assessment, solutions, and design guidelines.
Carminati, M., Montagnani, G.L., Occhipinti, M., Kuehne, A., Niendorf, T., Nagy, K., Nagy, A., Czeller, M. and Fiorini, C.
IEEE Transactions on Radiation and Plasma Medical Sciences 2 (4): 369-379. July 2018

A global ocean atlas of eukaryotic genes.
Carradec, Q., Pelletier, E., Da Silva, C., Alberti, A., Seeleuthner, Y., Blanc-Mathieu, R., Lima-Mendez, G., Rocha, F., Tirichine, L., Labadie, K., Kirilovsky, A., Bertrand, A., Engelen, S., Madoui, M.A., Méheust, R., Poulain, J., Romac, S., Richter, D.J., Yoshikawa, G., Dimier, C., Kandels-Lewis, S., Picheral, M., Searson, S., Jaillon, O., Aury, J.M., Karsenti, E., Sullivan, M.B., Sunagawa, S., Bork, P., Not, F., Hingamp, P., Raes, J., Guidi, L., Ogata, H., De Vargas, C., Iudicone, D., Bowler, C. and Wincker, P.
Nature Communications 9 (1): 373. 25 January 2018

Sustained MAPK/ERK activation in adult Schwann cells impairs nerve repair.
Cervellini, I., Galino, J., Zhu, N., Allen, S., Birchmeier, C. and Bennett, D.L.
Journal of Neuroscience 38 (3): 679-690. 17 January 2018

Multiscale modeling and numerical simulation of calcium cycling in cardiac myocytes.
Chamakuri, N., Neubert, W., Gilbert, S., Vierheller, J., Warnecke, G. and Falcke, M.
Multiscale Modeling & Simulation 16 (3): 1115-1145. 12 July 2018

Longitudinal study of multiple sclerosis lesions using ultra-high field (7T) multiparametric MR imaging.
Chawla, S., Kister, I., Sinnecker, T., Wuerfel, J., Brisset, J.C., Paul, F. and Ge, Y.
PLoS ONE 13 (9): e0202918. 13 September 2018

Adaptive and reversible resistance to Kras inhibition in pancreatic cancer cells.
Chen, P.Y., Muzumdar, M.D., Dorans, K.J., Robbins, R.A., Bhutkar, A., Del Rosario, A.M., Mertins, P., Qiao, J., Schaefer, C., Gertler, F.B., Carr, S.A. and Jacks, T.
Cancer Research 78 (4): 985-1002. 15 February 2018

Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways.
Chen, W., Kang, K.L., Alshaikh, A., Varma, S., Lin, Y.L., Shin, K.H., Kim, R., Wang, C.Y., Park, N.H., Walentin, K., Schmidt-Ott, K.M. and Kang, M.K.
Oncogenesis 7 (5): 38. 8 May 2018

Human papillomavirus 16 E6 induces FoxM1B in oral keratinocytes through GRHL2.
Chen, W., Shimane, T., Kawano, S., Alshaikh, A., Kim, S.Y, Chung, S.H., Kim, R.H., Shin, K.H., Walentin, K., Park, N.H., Schmidt-Ott, K.M. and Kang, M.K.
Journal of Dental Research 97 (7): 795-802. 1 July 2018

Perivascular adipose tissue: the sixth man of the cardiovascular system.
Cheng, C.K., Bakar, H.A., Gollasch, M. and Huang, Y.
Cardiovascular Drugs and Therapy 32 (5): 481-502. October 2018

Pervasive, coordinated protein-level changes driven by transcript isoform switching during meiosis.
Cheng, Z., Otto, G.M., Powers, E.N., Keskin, A., Mertins, P., Carr, S.A., Jovanovic, M. and Brar, G.A.
Cell 172 (5): 910-923. 22 February 2018

Measurement of intracellular concentration of fluorescently-labeled targets in living cells.
Cherkas, V., Grebenyuk, S., Osypenko, D., Dovgan, A.V., Grushevskyi, E.O., Yedutenko, M., Sheremet, Y., Dromaretsky, A., Bozhenko, A., Agashkov, K., Kononenko, N.I. and Belan, P.
PLoS ONE 13 (4): e0194031. 25 April 2018

NOTCH activity differentially affects alternative cell fate acquisition and maintenance.
Cheung, L., Le Tissier, P., Goldsmith, S.G., Treier, M., Lovell-Badge, R. and Rizzoti, K.
eLife 7 : e33318. 26 March 2018

The scaling features of the 3D organization of chromosomes are highlighted by a transformation à la Kadanoff of Hi-C data.
Chiariello, A.M., Bianco, S., Annunziatella, C., Esposito, A. and Nicodemi, M.
EPL 120 (4): 40004. 8 February 2018

MRI-based methods for spinal cord atrophy evaluation: a comparison of cervical cord cross-sectional area, cervical cord volume, and full spinal cord volume in patients with aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders.
Chien, C., Brandt, A.U., Schmidt, F., Bellmann-Strobl, J., Ruprecht, K., Paul, F. and Scheel, M.
American Journal of Neuroradiology 39 (7): 1362-1368. 1 July 2018

Genome engineering using Sleeping Beauty transposition in vertebrates.
Chilkunda, S.S., Raghunathan, V., Narayanavari, S.A., Ivics, Z. and Izsvák, Z.
In: Genome editing and engineering. Cambridge University Press, Cambridge, 249-269. ISBN 9781316756300 July 2018

Cardiac pacemaker channel (HCN4) inhibition and atrial arrhythmogenesis after releasing cardiac sympathetic activation.
Chobanyan-Jürgens, K., Heusser, K., Duncker, D., Veltmann, C., May, M., Mehling, H., Luft, F.C., Schröder, C., Jordan, J. and Tank, J.
Scientific Reports 8 (1): 7748. 17 May 2018

Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4(+) and CD8(+) T cell responses.
Choi, I.K., Wang, Z., Ke, Q., Hong, M., Qian, Y., Zhao, X., Liu, Y., Kim, H.J., Ritz, J., Cantor, H., Rajewsky, K., Wucherpfennig, K.W. and Zhang, B.
Proceedings of the National Academy of Sciences of the United States of America 115 (4): E686-E695. January 2018

Intestinal electrolyte and fluid secretion: a model in trouble?
Cid, L.P., Jentsch, T.J. and Sepúlveda, F.V.
Journal of Physiology 596 (12): 2465-2466. 15 June 2018

Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon(+) α-cells.
Cigliola, V., Ghila, L., Thorel, F., van Gurp, L., Baronnier, D., Oropeza, D., Gupta, S., Miyatsuka, T., Kaneto, H., Magnuson, M.A., Osipovich, A.B., Sander, M., Wright, C.E.V., Thomas, M.K., Furuyama, K., Chera, S. and Herrera, P.L.
Nature Cell Biology 20 (11): 1267-1277. November 2018

B1a B cells require autophagy for metabolic homeostasis and self-renewal.
Clarke, A.J., Riffelmacher, T., Braas, D., Cornall, R.J. and Simon, A.K.
Journal of Experimental Medicine 215 (2): 399-413. 5 February 2018

Barreloid borders and neuronal activity shape panglial gap junction-coupled networks in the mouse thalamus.
Claus, L., Philippot, C., Griemsmann, S., Timmermann, A., Jabs, R., Henneberger, C., Kettenmann, H. and Steinhaeuser, C.
Cerebral Cortex 28 (1): 213-222. 1 January 2018

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR.
Clauss, J., Obenaus, M., Miskey, C., Ivics, Z., Izsvák, Z., Uckert, W. and Bunse, M.
Human Gene Therapy 29 (5): 569-584. May 2018

Similarity of the dog and human gut microbiomes in gene content and response to diet.
Coelho, L.P., Kultima, J.R., Costea, P.I., Fournier, C., Pan, Y., Czarnecki-Maulden, G., Hayward, M.R., Forslund, S.K., Schmidt, T.S.B., Descombes, P., Jackson, J.R., Li, Q. and Bork, P.
Microbiome 6 (1): 72. 19 April 2018

Multi-level proteomics identifies CT45 as a chemosensitivity mediator and immunotherapy target in ovarian cancer.
Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S.D., López-Méndez, B., Nilsson, J., Mund, A., Mann, M. and Curtis, M.
Cell 175 (1): 159-170. 20 September 2018

Enterotypes in the landscape of gut microbial community composition.
Costea, P.I., Hildebrand, F., Manimozhiyan, A., Baeckhed, F., Blaser, M.J., Bushman, F.D., de Vos, W.M., Ehrlich, S.D., Fraser, C.M., Hattori, M., Huttenhower, C., Jeffery, I.B., Knights, D., Lewis, J.D., Ley, R.E., Ochman, H., O'Toole, P.W., Quince, C., Relman, D.A., Shanahan, F., Sunagawa, S., Wang, J., Weinstock, G.M., Wu, G.D., Zeller, G., Zhao, L., Raes, J., Knight, R. and Bork, P.
Nature Microbiology 3 (1): 8-16. January 2018

Low-frequency and rare-coding variation contributes to multiple sclerosis risk.
Cotsapas, C.
Cell 175 (6): 1679-1687. 29 November 2018

MetExplore: collaborative edition and exploration of metabolic networks.
Cottret, L., Frainay, C., Chazalviel, M., Cabanettes, F., Gloaguen, Y., Camenen, E., Merlet, B., Heux, S., Portais, J.C., Poupin, N., Vinson, F. and Jourdan, F.
Nucleic Acids Research 46 (W1): W495-W502. 2 July 2018

Imaging of endothelial cell dynamic behavior in zebrafish.
Coxam, B. and Gerhardt, H.
Methods in Molecular Biology 1846 : 181-195. 2018

Acquisition and reconstruction of 4D surfaces of axolotl embryos with the flipping stage robotic microscope.
Crawford-Young, S.J., Dittapongpitch, S., Gordon, R. and Harrington, K.I.S.
Biosystems 173 : 214-220. November 2018

Polycystin-2-dependent control of cardiomyocyte autophagy.
Criollo, A., Altamirano, F., Pedrozo, Z., Schiattarella, G.G., Li, D.L., Rivera-Mejías, P., Sotomayor-Flores, C., Parra, V., Villalobos, E., Battiprolu, P.K., Jiang, N., May, H.I., Morselli, E., Somlo, S., de Smedt, H., Gillette, T.G., Lavandero, S. and Hill, J.A.
Journal of Molecular and Cellular Cardiology 118 : 110-121. May 2018

Artificial gene regulatory networks-a review.
Cussat-Blanc, S., Harrington, K. and Banzhaf, W.
Artificial Life 24 (4): 296-328. 2018

Scientists on the Spot: Salt, the microbiome, and cardiovascular diseases.
Czesnikiewicz-Guzik, M. and Mueller, D.N.
Cardiovascular Research 114 (10): e72-e73. 1 August 2018

The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages.
Czimmerer, Z., Daniel, B., Horvath, A., Rückerl, D., Nagy, G., Kiss, M., Peloquin, M., Budai, M.M., Cuaranta-Monroy, I., Simandi, Z., Steiner, L., Nagy, B., Poliska, S., Banko, C., Bacso, Z., Schulman, I.G., Sauer, S., Deleuze, J.F., Allen, J.E., Benko, S. and Nagy, L.
Immunity 48 (1): 75-90. 16 January 2018

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.
Czimmerer, Z., Nagy, Z.S., Nagy, G., Horvath, A., Silye-Cseh, T., Kriston, A., Jonas, D., Sauer, S., Steiner, L., Daniel, B., Deleuze, J.F. and Nagy, L.
Molecular and Cellular Endocrinology 471 : 63-74. 15 August 2018

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Genome-wide analysis of barrett's adenocarcinoma. a first step towards identifying patients at risk and developing therapeutic paths.
Dai, Y., Wang, Q., Gonzalez Lopez, A., Anders, M., Malfertheiner, P., Vieth, M. and Kemmner, W.
Translational Oncology 11 (1): 116-124. February 2018

Randomized, phase 3 trial of inotuzumab ozogamicin plus rituximab versus chemotherapy plus rituximab for relapsed/refractory aggressive B-cell non-Hodgkin lymphoma.
Dang, N.H., Ogura, M., Castaigne, S., Fayad, L.E., Jerkeman, M., Radford, J., Pezzutto, A., Bondarenko, I., Stewart, D.A., Shnaidman, M., Sullivan, S., Vandendries, E., Tobinai, K., Ramchandren, R., Hamlin, P.A., Giné, E. and Ando, K.
British Journal of Haematology 182 (4): 583-586. August 2018

The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory.
Daniel, B., Nagy, G., Czimmerer, Z., Horvath, A., Hammers, D.W., Cuaranta-Monroy, I., Poliska, S., Tzerpos, P., Kolostyak, Z., Hays, T.T., Patsalos, A., Houtman, R., Sauer, S., Francois-Deleuze, J., Rastinejad, F., Balint, B.L., Sweeney, H.L. and Nagy, L.
Immunity 49 (4): 615-626. 16 October 2018

The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.
Daniel, B., Nagy, G., Horvath, A., Czimmerer, Z., Cuaranta-Monroy, I., Poliska, S., Hays, T.T., Sauer, S., Francois-Deleuze, J. and Nagy, L.
Nucleic Acids Research 46 (9): 4425-4439. 18 May 2018

iPath3.0: interactive pathways explorer v3.
Darzi, Y., Letunic, I., Bork, P. and Yamada, T.
Nucleic Acids Research 46 (W1): W510-W513. 2 July 2018

ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis.
Das, K.K., Heeg, S., Pitarresi, J.R., Reichert, M., Bakir, B., Takano, S., Kopp, J.L., Wahl-Feuerstein, A., Hicks, P., Sander, M. and Rustgi, A.K.
Developmental Dynamics 247 (6): 854-866. June 2018

Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4.
Dauksaite, V. and Gotthardt, M.
Nucleic Acids Research 46 (10): 5227-5238. 1 June 2018

Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability.
Dawes, J.M., Weir, G.A., Middleton, S.J., Patel, R., Chisholm, K.I., Pettingill, P., Peck, L.J., Sheridan, J., Shakir, A., Jacobson, L., Gutierrez-Mecinas, M., Galino, J., Walcher, J., Kühnemund, J., Kuehn, H., Sanna, M.D., Lang, B., Clark, A.J., Themistocleous, A.C., Iwagaki, N., West, S.J., Werynska, K., Carroll, L., Trendafilova, T., Menassa, D.A., Giannoccaro, M.P., Coutinho, E., Cervellini, I., Tewari, D., Buckley, C., Leite, M.I., Wildner, H., Zeilhofer, H.U., Peles, E., Todd, A.J., McMahon, S.B., Dickenson, A.H., Lewin, G.R., Vincent, A. and Bennett, D.L.
Neuron 97 (4): 806-822. 21 February 2018

EGFR activation triggers cellular hypertrophy and lysosomal disease in NAGLU-depleted cardiomyoblasts, mimicking the hallmarks of mucopolysaccharidosis IIIB.
De Pasquale, V., Pezone, A., Sarogni, P., Tramontano, A., Schiattarella, G.G., Avvedimento, V.E., Paladino, S. and Pavone, L.M.
Cell Death & Disease 9 (2): 40. 18 January 2018

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Decaesteker, B., Denecker, G., Van Neste, C., Dolman, E.M., Van Loocke, W., Gartlgruber, M., Nunes, C., De Vloed, F., Depuydt, P., Verboom, K., Rombaut, D., Loontiens, S., De Wyn, J., Kholosy, W.M., Koopmans, B., Essing, A.H.W., Herrmann, C., Dreidax, D., Durinck, K., Deforce, D., van Nieuwerburgh, F., Henssen, A., Versteeg, R., Boeva, V., Schleiermacher, G., van Nes, J., Mestdagh, P., Vanhauwaert, S., Schulte, J.H., Westermann, F., Molenaar, J.J., De Preter, K. and Speleman, F.
Nature Communications 9 (1): 4866. 19 November 2018

The chromatin reader ZMYND8 regulates Igh enhancers to promote immunoglobulin class switch recombination.
Delgado-Benito, V., Rosen, D.B., Wang, Q., Gazumyan, A., Pai, J.A., Oliveira, T.Y., Sundaravinayagam, D., Zhang, W., Andreani, M., Keller, L., Kieffer-Kwon, K.R., Pękowska, A., Jung, S., Driesner, M., Subbotin, R.I., Casellas, R., Chait, B.T., Nussenzweig, M.C. and Di Virgilio, M.
Molecular Cell 72 (4): 636-649. 15 November 2018

Stage-specific metabolic features of differentiating neurons: implications for toxicant sensitivity.
Delp, J., Gutbier, S., Cerff, M., Zasada, C., Niedenführ, S., Zhao, L., Smirnova, L., Hartung, T., Borlinghaus, H., Schreiber, F., Bergemann, J., Gätgens, J., Beyss, M., Azzouzi, S., Waldmann, T., Kempa, S., Nöh, K. and Leist, M.
Toxicology and Applied Pharmacology 354 : 64-80. 1 September 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais, F., Margaritte-Jeannin, P., Barnes, K.C., Cookson, W.O.C., Altmüller, J., Ang, W., Barr, R.G., Beaty, T.H., Becker, A.B., Beilby, J., Bisgaard, H., Bjornsdottir, U.S., Bleecker, E., Bonnelykke, K., Boomsma, D.I., Bouzigon, E., Brightling, C.E., Brossard, M., Brusselle, G.G., Burchard, E., Burkart, K.M., Bush, A., Chan-Yeung, M., Chung, K.F., Couto Alves, A., Curtin, J.A., Custovic, A., Daley, D., de Jongste, J.C., Del-Rio-Navarro, B.E., Donohue, K.M., Duijts, L., Eng, C., Eriksson, J.G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M.A., Freidin, M.B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S.A, Gilliland, F., Granell, R., Graves, P.E., Gudbjartsson, D.F., Haahtela, T., Heckbert, S.R., Heederik, D., Heinrich, J., Helioevaara, M., Henderson, J., Himes, B.E., Hirose, H., Hirschhorn, J.N., Hofman, A., Holt, P., Hottenga, J., Hudson, T.J., Hui, J., Imboden, M., Ivanov, V., Jaddoe, V.W.V., James, A., Janson, C., Jarvelin, M.R., Jarvis, D., Jones, G., Jonsdottir, I., Jousilahti, P., Kabesch, M., Kähönen, M., Kantor, D.B., Karunas, A.S., Khusnutdinova, E., Koppelman, G.H., Kozyrskyj, A.L., Kreiner, E., Kubo, M., Kumar, R., Kumar, A., Kuokkanen, M., Lahousse, L., Laitinen, T., Laprise, C., Lathrop, M., Lau, S., Lee, Y.A., Lehtimaeki, T., Letort, S., Levin, A.M., Li, G., Liang, L., Loehr, L.R., London, S.J., Loth, D.W., Manichaikul, A., Marenholz, I., Martinez, F.J., Matheson, M.C., Mathias, R.A., Matsumoto, K., Mbarek, H., McArdle, W.L., Melbye, M., Melen, E., Meyers, D., Michel, S., Mohamdi, H., Musk, A.W., Myers, R.A., Nieuwenhuis, M.A.E., Noguchi, E., O'Connor, G.T., Ogorodova, L.M., Palmer, C.D., Palotie, A., Park, J.E., Pennell, C.E., Pershagen, G., Polonikov, A., Postma, D.S., Probst-Hensch, N., Puzyrev, V.P., Raby, B.A., Raitakari, O.T., Ramasamy, A., Rich, S.S., Robertson, C.F., Romieu, I., Salam, M.T., Salomaa, V., Schluenssen, V., Scott, R., Selivanova, P.A., Sigsgaard, T., Simpson, A., Siroux, V., Smith, L.J., Solodilova, M., Standl, M., Stefansson, K., Strachan, D.P., Stricker, B.H., Takahashi, A., Thompson, P.J., Thorleifsson, G., Thorsteinsdottir, U., Tiesler, C.M.T., Torgerson, D.G., Tsunoda, T., Uitterlinden, A.G., van der Valk, R.J.P., Vaysse, A., Vedantam, S., von Berg, A., von Mutius, E., Vonk, J.M., Waage, J., Wareham, N.J., Weiss, S.T., White, W.B., Wickman, M., Widén, E., Willemsen, G., Williams, L.K., Wouters, I.M., Yang, J.J., Zhao, J.H., Moffatt, M.F., Ober, C. and Nicolae, D.L.
Nature Genetics 50 (1): 42-53. January 2018

Nuclear organization in the spinal cord depends on motor neuron lamination orchestrated by catenin and afadin function.
Dewitz, C., Pimpinella, S., Hackel, P., Akalin, A., Jessell, T.M. and Zampieri, N.
Cell Reports 22 (7): 1681-1694. 13 February 2018

Spatiotemporal m(i)RNA architecture and 3' UTR regulation in the C. elegans germline.
Diag, A., Schilling, M., Klironomos, F., Ayoub, S. and Rajewsky, N.
Developmental Cell 47 (6): 785-800. 17 December 2018

Muscle MRI in patients with dysferlinopathy: pattern recognition and implications for clinical trials.
Diaz-Manera, J., Fernandez-Torron, R., LLauger, J., James, M.K., Mayhew, A., Smith, F.E., Moore, U.R., Blamire, A.M., Carlier, P.G., Rufibach, L., Mittal, P., Eagle, M., Jacobs, M., Hodgson, T., Wallace, D., Ward, L., Smith, M., Stramare, R., Rampado, A., Sato, N., Tamaru, T., Harwick, B., Rico Gala, S., Turk, S., Coppenrath, E.M., Foster, G., Bendahan, D., Le Fur, Y., Fricke, S.T., Otero, H., Foster, S.L., Peduto, A., Sawyer, A.M., Hilsden, H., Lochmuller, H., Grieben, U., Spuler, S., Tesi Rocha, C., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Harms, M., Pestronk, A., Krause, S., Schreiber-Katz, O., Walter, M.C., Paradas, C., Hogrel, J.Y., Stojkovic, T., Takeda, S., Mori-Yoshimura, M., Bravver, E., Sparks, S., Bello, L., Semplicini, C., Pegoraro, E., Mendell, J.R., Bushby, K. and Straub, V.
Journal of Neurology Neurosurgery and Psychiatry 89 (10): 1071-1081. October 2018

Apical and basal matrix remodeling control epithelial morphogenesis.
Diaz-de-la-Loza, M.D.C., Ray, R.P., Ganguly, P.S., Alt, S., Davis, J.R., Hoppe, A., Tapon, N., Salbreux, G. and Thompson, B.J.
Developmental Cell 46 (1): 23-39. 2 July 2018

Structural changes of TasA in biofilm formation of Bacillus subtilis.
Diehl, A., Roske, Y., Ball, L., Chowdhury, A., Hiller, M., Molière, N., Kramer, R., Stöppler, D., Worth, C.L., Schlegel, B., Leidert, M., Cremer, N., Erdmann, N., Lopez, D., Stephanowitz, H., Krause, E., van Rossum, B.J., Schmieder, P., Heinemann, U., Turgay, K., Akbey, Ü. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 115 (13): 3237-3242. 27 March 2018

A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire.
Dobeš, J., Edenhofer, F., Vobořil, M., Brabec, T., Dobešová, M., Čepková, A., Klein, L., Rajewsky, K. and Filipp, D.
European Journal of Immunology 48 (3): 546-548. March 2018

On the relation between filament density, force generation and protrusion rate in mesenchymal cell motility.
Dolati, S., Kage, F., Mueller, J., Müsken, M., Kirchner, M., Dittmar, G., Sixt, M., Rottner, K. and Falcke, M.
Molecular Biology of the Cell 29 (22): 2674-2686. 1 November 2018

Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient.
Doll, S., Kriegmair, M.C., Santos, A., Wierer, M., Coscia, F., Neil, H.M., Porubsky, S., Geyer, P.E., Mund, A., Nuhn, P. and Mann, M.
Molecular Oncology 12 (8): 1296-1307. August 2018

Neuronal adenosine A(2A) receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease.
Domenici, M.R., Chiodi, V., Averna, M., Armida, M., Pèzzola, A., Pepponi, R., Ferrante, A., Bader, M., Fuxe, K. and Popoli, P.
Purinergic Signalling 14 (3): 235-243. September 2018

Hippocampal ripple oscillations and inhibition-first network models: frequency dynamics and response to GABA modulators.
Donoso, J.R., Schmitz, D., Maier, N. and Kempter, R.
Journal of Neuroscience 38 (12): 3124-3146. 21 March 2018

How has microbiology changed over the past 25 years?
Doolittle, W.F., Finlay, B.B., Fischetti, V.A., Kaufmann, S.H.E., Sasakawa, C. and Sattentau, Q.
Trends in Microbiology 26 (4): 246-250. April 2018

omniCLIP: probabilistic identification of protein-RNA interactions from CLIP-seq data.
Drewe-Boss, P., Wessels, H.H. and Ohler, U.
Genome Biology 19 : 183. 1 November 2018

Arrhythmogenic remodeling of the left ventricle in a porcine model of repaired tetralogy of fallot.
Dubes, V., Benoist, D., Roubertie, F., Gilbert, S.H., Constantin, M., Charron, S., Elbes, D., Vieillot, D., Quesson, B., Cochet, H., Haïssaguerre, M., Rooryck, C., Bordachar, P., Thambo, J.B. and Bernus, O.
Circulation Arrhythmia and Electrophysiology 11 (10): e006059. October 2018

S-palmitoylation is required for the control of growth cone morphology of DRG neurons by CNP-induced cGMP signaling.
Dumoulin, A., Dagane, A., Dittmar, G. and Rathjen, F.G.
Frontiers in Molecular Neuroscience 11 : 345. 24 September 2018

Molecular analysis of sensory axon branching unraveled a cGMP-dependent signaling cascade.
Dumoulin, A., Ter-Avetisyan, G., Schmidt, H. and Rathjen, F.G.
International Journal of Molecular Sciences 19 (5): 1266. 24 April 2018

In vivo imaging of MMP-13 activity using a specific polymer-FRET peptide conjugate detects early osteoarthritis and inhibitor efficacy.
Duro-Castano, A., Lim, N.H., Tranchant, I., Amoura, M., Beau, F., Wieland, H., Kingler, O., Herrmann, M., Nazaré, M., Plettenburg, O., Dive, V., Vicent, M.J. and Nagase, H.
Advanced Functional Materials 28 (37): 1802738. 12 September 2018

Brain iron accumulation in Wilson's disease: a longitudinal imaging case study during anticopper treatment using 7.0T MRI and transcranial sonography.
Dusek, P., Skoloudik, D., Maskova, J., Huelnhagen, T., Bruha, R., Zahorakova, D., Niendorf, T., Ruzicka, E., Schneider, S.A. and Wuerfel, J.
Journal of Magnetic Resonance Imaging 47 (1): 282-285. January 2018

Glutamate uptake and release at single adult corticostriatal synapses of normal and Huntington mice.
Dvorzhak, A., Helassa, N., Torok, K., Schmitz, D. and Grantyn, R.
bioRxiv : 455758. 30 October 2018

Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care.
Döhner, H., Dolnik, A., Tang, L., Seymour, J.F., Minden, M.D., Stone, R.M., Del Castillo, T.B., Al-Ali, H.K., Santini, V., Vyas, P., Beach, C L., MacBeth, K.J., Skikne, B.S., Songer, S., Tu, N., Bullinger, L. and Dombret, H.
Leukemia 32 (12): 2546-2557. December 2018

Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.
Döhner, K., Ramos-Nascimento, A., Bialy, D., Anderson, F., Hickford-Martinez, A., Rother, F., Koithan, T., Rudolph, K., Buch, A., Prank, U., Binz, A., Hügel, S., Lebbink, R.J., Hoeben, R.C., Hartmann, E., Bader, M., Bauerfeind, R. and Sodeik, B.
PLoS Pathogens 14 (1): e1006823. 5 January 2018

Disease modification in multiple sclerosis by flupirtine - results of a randomized placebo controlled phase II trial.
Dörr, J., Wernecke, K.D., Würfel, J., Bellmann-Strobl, J., Siffrin, V., Sättler, M.B., Simons, M., Linsa, A., Tumani, H. and Paul, F.
Frontiers in Neurology 9 : 842. October 2018

Cardioprotective effect of thyroid hormone is mediated by AT2 receptor and involves nitric oxide production via Akt activation in mice.
da Silva, I.B., Gomes, D.A., Alenina, N., Bader, M., dos Santos, R.A. and Barreto-Chaves, M.L.M.
Heart and Vessels 33 (6): 671-681. June 2018

Alamandine acts via MrgD to induce AMPK/NO activation against Ang II hypertrophy in cardiomyocytes.
de Jesus, I.C.G., Scalzo, S., Alves, F., Marques, K., Rocha-Resende, C., Bader, M., Santos, R.A.S. and Guatimosim, S.
American Journal of Physiology Cell Physiology 314 (6): C702-C711. June 2018

E

Spatial transcriptomics of C. elegans males and hermaphrodites identifies sex-specific differences in gene expression patterns.
Ebbing, A., Vértesy, Á., Betist, M.C., Spanjaard, B., Junker, J.P., Berezikov, E., van Oudenaarden, A. and Korswagen, H.C.
Developmental Cell 47 (6): 801-813. 17 December 2018

Silent witness: dual-species transcriptomics reveals epithelial immunological quiescence to helminth larval encounter and fostered larval development.
Ebner, F., Kuhring, M., Radonic, A., Midha, A., Renard, B.Y. and Hartmann, S.
Frontiers in Immunology 9 : 1868. 15 August 2018

Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit.
Edemann-Callesen, H., Habelt, B., Wieske, F., Jackson, M., Khadka, N., Mattei, D., Bernhardt, N., Heinz, A., Liebetanz, D., Bikson, M., Padberg, F., Hadar, R., Nitsche, N. and Winter, C.
Translational Psychiatry 8 (1): 11. 10 January 2018

Crosstalk between core-multishell nanocarriers for cutaneous drug delivery and antigen-presenting cells of the skin.
Edlich, A., Volz, P., Brodwolf, R., Unbehauen, M., Mundhenk, L., Gruber, A.D., Hedtrich, S., Haag, R., Alexiev, U. and Kleuser, B.
Biomaterials 162 : 60-70. April 2018

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.
Eggert, S., Gonzalez, A.C., Thomas, C., Schilling, S., Schwarz, S.M., Tischer, C., Adam, V., Strecker, P., Schmidt, V., Willnow, T.E., Hermey, G., Pietrzik, C.U., Koo, E.H. and Kins, Stefan
Cellular and Molecular Life Sciences 75 (2): 301-322. January 2018

Antiproliferative activity of the combination of doxorubicin/quercetin on MCF7 breast cancer cell line: a combined study using colorimetric assay and synchrotron infrared microspectroscopy.
Elmadany, N., Khalil, E., Vaccari, L., Birarda, G., Yousef, I. and Abu-Dahab, R.
Infrared Physics & Technology 95 : 141-147. December 2018

Roles of A-kinase anchoring proteins and phosphodiesterases in the cardiovascular system.
Ercu, M. and Klussmann, E.
Journal of Cardiovascular Development and Disease 5 (1): 14. 20 February 2018

Viral communities among sympatric vampire bats and cattle.
Escalera-Zamudio, M., Taboada, B., Rojas-Anaya, E., Löber, U., Loza-Rubio, E., Arias, C.F. and Greenwood, A.D.
EcoHealth 15 (1): 132-142. March 2018

Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.
Escot, S., Willnow, D., Naumann, H., Di Francescantonio, S. and Spagnoli, F.M.
Nature Communications 9 (1): 5082. 30 November 2018

F

Struktur und Funktion des mechanochemischen Motorproteins Dynamin.
Faelber, K. and Daumke, O.
BIOspektrum 24 (5): 481-483. September 2018

The stretch to stray on time: resonant length of random walks in a transient.
Falcke, M. and Friedhoff, V.N.
Chaos 28 (5): 053117. 23 May 2018

On the phase space structure of IP(3) induced Ca(2+) signalling and concepts for predictive modeling.
Falcke, M., Moein, M., Tilūnaitė, A., Thul, R. and Skupin, A.
Chaos 28 (4): 045115. 1 April 2018

Differential targeting and signalling of voltage-gated T-type Ca(V) 3.2 and L-type Ca(V) 1.2 channels to ryanodine receptors in mesenteric arteries.
Fan, G., Kaßmann, M., Hashad, A.M., Welsh, D.G. and Gollasch, M.
Journal of Physiology 596 (20): 4863-4877. 15 October 2018

A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit via FRET in a binary system.
Fang, G.M., Chamiolo, J., Kankowski, S., Hövelmann, F., Friedrich, D., Löwer, A., Meier, J.C. and Seitz, O.
Chemical Science 9 (21): 4794-4800. 7 June 2018

Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity.
Farsi, Z., Gowrisankaran, S., Krunic, M., Rammner, B., Woehler, A., Lafer, E.M., Mim, C., Jahn, R. and Milosevic, I.
eLife 7 : e32569. 13 April 2018

Dominant SCN2A mutation causes familial episodic ataxia and impairment of speech development.
Fazeli, W., Becker, K., Herkenrath, P., Düchting, C., Körber, F., Landgraf, P., Nürnberg, P., Altmüller, J., Thiele, H., Koy, A., Liebau, M.C., Simon, T., Dötsch, J. and Cirak, S.
Neuropediatrics 49 (6): 379-384. December 2018

Association of obesity, diabetes and hypertension with cognitive impairment in older age.
Feinkohl, I., Lachmann, G., Brockhaus, W.R., Borchers, F., Piper, S.K., Ottens, T., Nathoe, H., Sauer, A.M., Dieleman, J., Radtke, F., van Dijk, D., Pischon, T. and Spies, C.
Clinical Epidemiology 10 : 853-862. 25 July 2018

Associations of dyslipidaemia and lipid-lowering treatment with risk of postoperative cognitive dysfunction: a systematic review and meta-analysis.
Feinkohl, I., Winterer, G. and Pischon, T.
Journal of Epidemiology and Community Health 72 (6): 499-506. 10 May 2018

Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients.
Feldheim, J., Kessler, A.F., Schmitt, D., Wilczek, L., Linsenmann, T., Dahlmann, M., Monoranu, C.M., Ernestus, R.I., Hagemann, C. and Löhr, M.
OncoTargets and Therapy 11 : 8673-8684. 4 December 2018

Continuous addition of progenitors forms the cardiac ventricle in zebrafish.
Felker, A., Prummel, K.D., Merks, A.M., Mickoleit, M., Brombacher, E.C., Huisken, J., Panáková, D. and Mosimann, C.
Nature Communications 9 (1): 2001. 21 May 2018

A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism.
Fernandes-Rosa, F.L., Daniil, G., Orozco, I.J., Göppner, C., El Zein, R., Jain, V., Boulkroun, S., Jeunemaitre, X., Amar, L., Lefebvre, H., Schwarzmayr, T., Strom, T.M., Jentsch, T.J. and Zennaro, M.C.
Nature Genetics 50 (3): 355-361. March 2018

Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice.
Fernández, Á.F., Sebti, S., Wei, Y., Zou, Z., Shi, M., McMillan, K.L., He, C., Ting, T., Liu, Y., Chiang, W.C., Marciano, D.K., Schiattarella, G.G., Bhagat, G., Moe, O.W., Hu, M.C. and Levine, B.
Nature 558 (7708): 136-140. 7 June 2018

Role of perivascular adipose tissue in health and disease.
Fernández-Alfonso, M.S., Somoza, B., Tsvetkov, D., Kuczmanski, A., Dashwood, M. and Gil-Ortega, M.
Comprehensive Physiology 8 (1): 23-59. January 2018

Dendrite-specific amplification of weak synaptic input during network activity in vivo.
Ferrarese, L., Jouhanneau, J.S., Remme, M.W.H., Kremkow, J., Katona, G., Rózsa, B., Schreiber, S. and Poulet, J.F.A.
Cell Reports 24 (13): 3455-3465. 25 September 2018

Cardiovascular magnetic resonance in nonischemic myocardial inflammation: expert recommendations.
Ferreira, V.M., Schulz-Menger, J., Holmvang, G., Kramer, C.M., Carbone, I., Sechtem, U., Kindermann, I., Gutberlet, M., Cooper, L.T., Liu, P. and Friedrich, M.G.
Journal of the American College of Cardiology 72 (24): 3158-3176. 18 December 2018

A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors.
Fink, S., Zugelder, L., Roth, B., Brandt, E., Meloche, S., Izsvák, Z., Bargou, R.C. and Stühmer, T.
PLoS ONE 13 (10): e0205585. 19 October 2018

Association of visual impairment in neuromyelitis optica spectrum disorder with visual network reorganization.
Finke, C., Zimmermann, H., Pache, F., Oertel, F.C., Chavarro, V.S., Kramarenko, Y., Bellmann-Strobl, J., Ruprecht, K., Brandt, A.U. and Paul, F.
JAMA Neurology 75 (3): 296-303. March 2018

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level.
Fischer, J., Kleinau, G., Rutz, C., Zwanziger, D., Khajavi, N., Müller, A., Rehders, M., Brix, K., Worth, C.L., Führer, D., Krude, H., Wiesner, B., Schülein, R. and Biebermann, H.
Cellular and Molecular Life Sciences 75 (12): 2227-2239. June 2018

Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts.
Floegel, A., Kühn, T., Sookthai, D., Johnson, T., Prehn, C., Rolle-Kampczyk, U., Otto, W., Weikert, C., Illig, T., von Bergen, M., Adamski, J., Boeing, H., Kaaks, R. and Pischon, T.
European Journal of Epidemiology 33 (1): 55-66. January 2018

Gearing up to handle the mosaic nature of life in the quest for orthologs.
Forslund, K., Pereira, C., Capella-Gutierrez, S., Sousa da Silva, A., Altenhoff, A., Huerta-Cepas, J., Muffato, M., Patricio, M., Vandepoele, K., Ebersberger, I., Blake, J., Fernández Breis, J.T., Boeckmann, B., Gabaldón, T., Sonnhammer, E., Dessimoz, C. and Lewis, S.
Bioinformatics 34 (2): 323-329. 15 January 2018

Studies of the bugs within: telling sickness from cure.
Forslund, S.K. and Pedersen, O.
TheScienceBreaker 4 (1) 20 March 2018

Keratinocyte-specific ablation of protease-activated receptor-2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease.
Francis, N., Ayodele, B.A., O'Brien-Simpson, N.M., Birchmeier, W., Pike, R.N., Pagel, C.N. and Mackie, E.J.
Cellular Microbiology 20 (11): e12891. November 2018

Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
Franko, A., Rodriguez Camargo, D.C., Böddrich, A., Garg, D., Rodriguez Camargo, A., Rathkolb, B., Janik, D., Aichler, M., Feuchtinger, A., Neff, F., Fuchs, H., Wanker, E.E., Reif, B., Häring, H.U., Peter, A. and Hrabě de Angelis, M.
Scientific Reports 8 (1): 1116. 18 January 2018

Circular RNAs: a new class of biomarkers as a rising interest in laboratory medicine.
Franz, A., Rabien, A., Stephan, C., Ralla, B., Fuchs, S., Jung, K. and Fendler, A.
Clinical Chemistry and Laboratory Medicine 56 (12): 1992-2003. December 2018

MYB induces the expression of the oncogenic corepressor SKI in acute myeloid leukemia.
Frech, M., Teichler, S., Feld, C., Bouchard, C., Berberich, H., Sorg, K., Mernberger, M., Bullinger, L., Bauer, U.M. and Neubauer, A.
Oncotarget 9 (32): 22423-22435. 27 April 2018

FENS Forum 2018 - Neuer Teilnehmer-Rekord.
Friauf, E. and Kettenmann, H.
Neuroforum 24 (4): 297-299. 9 November 2018

Human axial progenitors generate trunk neural crest cells in vitro.
Frith, T.J.R., Granata, I., Wind, M., Stout, E., Thompson, O., Neumann, K., Stavish, D., Heath, P.R., Ortmann, D., Hackland, J.O.S., Anastassiadis, K., Gouti, M., Briscoe, J., Wilson, V., Johnson, S.L., Placzek, M., Guarracino, M.R., Andrews, P.W. and Tsakiridis, A.
eLife 7 : e35786. 10 August 2018

Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations.
Fritsche-Guenther, R., Zasada, C., Mastrobuoni, G., Royla, N., Rainer, R., Roßner, F., Pietzke, M., Klipp, E., Sers, C. and Kempa, S.
Scientific Reports 8 (1): 9204. 15 June 2018

IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies.
Fung, H.Y.J., Birol, M. and Rhoades, E.
Current Opinion in Structural Biology 49 : 36-43. April 2018

Quantification of the left atrium applying cardiovascular magnetic resonance in clinical routine.
Funk, S., Kermer, J., Doganguezel, S., Schwenke, C., von Knobelsdorff-Brenkenhoff, F. and Schulz-Menger, J.
Scandinavian Cardiovascular Journal 52 (2): 85-92. April 2018

G

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells.
Gabryšová, L., Alvarez-Martinez, M., Luisier, R., Cox, L.S., Sodenkamp, J., Hosking, C., Pérez-Mazliah, D., Whicher, C., Kannan, Y., Potempa, K., Wu, X., Bhaw, L., Wende, H., Sieweke, M.H., Elgar, G., Wilson, M., Briscoe, J., Metzis, V., Langhorne, J., Luscombe, N.M. and O'Garra, A.
Nature Immunology 19 (5): 497-507. May 2018

Safety and preliminary efficacy of deep transcranial magnetic stimulation in MS-related fatigue.
Gaede, G., Tiede, M., Lorenz, I., Brandt, A.U., Pfueller, C., Dörr, J., Bellmann-Strobl, J., Piper, S.K., Roth, Y., Zangen, A., Schippling, S. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 5 (1): e423. 1 January 2018

Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogels.
Gaetani, R., Aude, S., DeMaddalena, L.L., Strassle, H., Dzieciatkowska, M., Wortham, M., Bender, R.H.F., Nguyen-Ngoc, K.V., Schmid-Schöenbein, G.W., George, S.C., Hughes, C.C.W., Sander, M., Hansen, K.C. and Christman, K.L.
Tissue Engineering Part C Methods 24 (12): 697-708. December 2018

DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia.
Gaidzik, V.I., Weber, D., Paschka, P., Kaumanns, A., Krieger, S., Corbacioglu, A., Krönke, J., Kapp-Schwoerer, S., Krämer, D., Horst, H.A., Schmidt-Wolf, I., Held, G., Kündgen, A., Ringhoffer, M., Götze, K., Kindler, T., Fiedler, W., Wattad, M., Schlenk, R.F., Bullinger, L., Teleanu, V., Schlegelberger, B., Thol, F., Heuser, M., Ganser, A., Döhner, H. and Döhner, K.
Leukemia 32 (1): 30-37. January 2018

MVP: a microbe-phage interaction database.
Gao, N.L., Zhang, C., Zhang, Z., Hu, S., Lercher, M.J., Zhao, X.M., Bork, P., Liu, Z. and Chen, W.H.
Nucleic Acids Research 46 (D1): D700-D707. 4 January 2018

A novel form of RNA double helix based on G·U and C·A(+) wobble base pairing.
Garg, A. and Heinemann, U.
RNA 24 (2): 209-218. February 2018

Next-generation in vivo modeling of human cancers.
Gargiulo, G.
Frontiers in Oncology 8 : 429. October 2018

Downregulation of p53 drives autophagy during human trophoblast differentiation.
Gauster, M., Maninger, S., Siwetz, M., Deutsch, A., El-Heliebi, A., Kolb-Lenz, D., Hiden, U., Desoye, G., Herse, F. and Prokesch, A.
Cellular and Molecular Life Sciences 75 (10): 1839-1855. May 2018

Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus.
Gavvovidis, I., Leisegang, M., Willimsky, G., Miller, N.J., Nghiem, P. and Blankenstein, T.
Clinical Cancer Research 24 (15): 3644-3655. August 2018

Active contour method for ILM segmentation in ONH volume scans in retinal OCT.
Gawlik, K., Hausser, F., Paul, F., Brandt, A.U. and Kadas, E.M.
Biomedical Optics Express 9 (12): 6497. 1 December 2018

Integrated proteogenomic approach for identifying degradation motifs in eukaryotic cells.
Geffen, Y., Appleboim, A., Gardner, R.G. and Ravid, T.
Methods in Molecular Biology 1844 : 121-136. 2018

Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation.
Geissler, S., Textor, M., Stumpp, S., Seitz, S., Lekaj, A., Brunk, S., Klaassen, S., Schinke, T., Klein, C., Mundlos, S., Kornak, U. and Kühnisch, J.
PLoS ONE 13 (6): e0198510. 7 June 2018

First genome-wide CNV mapping in FELIS CATUS using next generation sequencing data.
Genova, F., Longeri, M., Lyons, L.A., Bagnato, A. and Strillacci, M.G.
BMC Genomics 19 (1): 895. 10 December 2018

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.
George, J., Walter, V., Peifer, M., Alexandrov, L.B., Seidel, D., Leenders, F., Maas, L., Müller, C., Dahmen, I., Delhomme, T.M., Ardin, M., Leblay, N., Byrnes, G., Sun, R., De Reynies, A., McLeer-Florin, A., Bosco, G., Malchers, F., Menon, R., Altmüller, J., Becker, C., Nürnberg, P., Achter, V., Lang, U., Schneider, P.M., Bogus, M., Soloway, M.G., Wilkerson, M.D., Cun, Y., McKay, J.D., Moro-Sibilot, D., Brambilla, C.G., Lantuejoul, S., Lemaitre, N., Soltermann, A., Weder, W., Tischler, V., Brustugun, O.T., Lund-Iversen, M., Helland, Å., Solberg, S., Ansén, S., Wright, G., Solomon, B., Roz, L., Pastorino, U., Petersen, I., Clement, J.H., Sänger, J., Wolf, J., Vingron, M., Zander, T., Perner, S., Travis, W.D., Haas, S.A., Olivier, M., Foll, M., Büttner, R., Hayes, D.N., Brambilla, E., Fernandez-Cuesta, L. and Thomas, R.K.
Nature Communications 9 (1): 1048. 13 March 2018

The current role of MRI in differentiating multiple sclerosis from its imaging mimics.
Geraldes, R., Ciccarelli, O., Barkhof, F., De Stefano, N., Enzinger, C., Filippi, M., Hofer, M., Paul, F., Preziosa, P., Rovira, A., DeLuca, G.C., Kappos, L., Yousry, T., Fazekas, F., Frederiksen, J., Gasperini, C., Sastre-Garriga, J., Evangelou, N. and Palace, J.
Nature Reviews Neurology 14 (4): 199-213. April 2018

Strand-seq enables reliable separation of long reads by chromosome via expectation maximization.
Ghareghani, M., Porubskỳ, D., Sanders, A.D., Meiers, S., Eichler, E.E., Korbel, J.O. and Marschall, T.
Bioinformatics 34 (13): i115-i123. 1 July 2018

Biallelic mutations in ADPRHL2, encoding ADP-ribosylhydrolase 3, lead to a degenerative pediatric stress-induced epileptic ataxia syndrome.
Ghosh, S.G., Becker, K., Huang, H., Dixon-Salazar, T., Chai, G., Salpietro, V., Al-Gazali, L., Waisfisz, Q., Wang, H., Vaux, K.K., Stanley, V., Manole, A., Akpulat, U., Weiss, M.M., Efthymiou, S., Hanna, M.G., Minetti, C., Striano, P., Pisciotta, L., De Grandis, E., Altmüller, J., Weixler, L., Nürnberg, P., Thiele, H., Yis, U., Okur, T.D., Polat, A.I., Amiri, N., Doosti, M., Karimani, E.G., Toosi, M.B., Haddad, G., Karakaya, M., Wirth, B., van Hagen, J.M., Wolf, N.I., Maroofian, R., Houlden, H., Cirak, S. and Gleeson, J.G.
American Journal of Human Genetics 103 (3): 431-439. 6 September 2018

Spatial modeling of the membrane-cytosolic interface in protein kinase signal transduction.
Giese, W., Milicic, G., Schröder, A. and Klipp, E.
PLoS Computational Biology 14 (4): e1006075. 9 April 2018

Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels.
Giulbudagian, M., Hönzke, S., Bergueiro, J., Işık, D., Schumacher, F., Saeidpour, S., Lohan, S.B., Meinke, M.C., Teutloff, C., Schäfer-Korting, M., Yealland, G., Kleuser, B., Hedtrich, S. and Calderón, M.
Nanoscale 10 (1): 469-479. 7 January 2018

Breaking the barrier - potent anti-inflammatory activity following efficient topical delivery of etanercept using thermoresponsive nanogels.
Giulbudagian, M., Yealland, G., Hönzke, S., Edlich, A., Geisendörfer, B., Kleuser, B., Hedtrich, S. and Calderón, M.
Theranostics 8 (2): 450-463. 1 January 2018

Near infrared spectroscopy setup for concurrent spectroscopic, invasive and MRI investigations in rats.
Gladytz, T., Hoppe, A., Cantow, K., Brix, S., Flemming, B., Pohlmann, A., Seeliger, E., Niendorf, T. and Grosenick, D.
In: Clinical and Translational Biophotonics, 3-6 April 2018, Los Angeles, United States of Amerika. 2018

NKp46 receptor-mediated interferon-γ production by natural killer cells increases fibronectin 1 to alter tumor architecture and control metastasis.
Glasner, A., Levi, A., Enk, J., Isaacson, B., Viukov, S., Orlanski, S., Scope, A., Neuman, T., Enk, C.D., Hanna, J.H., Sexl, V., Jonjic, S., Seliger, B., Zitvogel, L. and Mandelboim, O.
Immunity 48 (1): 107-119. 16 January 2018

Continuous blood glucose monitoring reveals enormous circadian variations in pregnant diabetic rats.
Golic, M., Kräker, K., Fischer, C., Alenina, N., Haase, N., Herse, F., Schütte, T., Henrich, W., Müller, D.N., Busjahn, A., Bader, M. and Dechend, R.
Frontiers in Endocrinology 9 : 271. 29 May 2018

Diabetes mellitus in pregnancy leads to growth restriction and epigenetic modification of the Srebf2 gene in rat fetuses.
Golic, M., Stojanovska, V., Bendix, I., Wehner, A., Herse, F., Haase, N., Kräker, K., Fischer, C., Alenina, N., Bader, M., Schütte, T., Schuchardt, M., van der Giet, M., Henrich, W., Muller, D.N., Felderhoff-Müser, U., Scherjon, S., Plösch, T. and Dechend, R.
Hypertension 71 (5): 911-920. May 2018

The case: chronic kidney disease unmasked by single-subject research.
Gollasch, B., Wischnewski, O., Rudolph, B., Anistan, Y.M., Luft, F.C. and Gollasch, M.
Case Reports in Nephrology and Dialysis 8 (2): 90-97. 16 May 2018

Dieter Klaus und die Bluthochdruckforschung.
Gollasch, M., Tsvetkov, D. and Müller, D.
Nieren- und Hochdruckkrankheiten 47 (1): 40-46. January 2018

Perivascular adipose tissue and the dynamic regulation of K(V)7 and K(ir) channels: implications to resistant hypertension.
Gollasch, M., Welsh, D.G. and Schubert, R.
Microcirculation 25 (1): e12434. January 2018

Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Gonçalves, I.C.G., Brecht, J., Thelen, M.P., Rehorst, W.A., Peters, M., Lee, H.J., Motameny, S., Torres-Benito, L., Ebrahimi-Fakhari, D., Kononenko, N.L., Altmüller, J., Vilchez, D., Sahin, M., Wirth, B. and Kye, M.J.
Scientific Reports 8 (1): 7907. 21 May 2018

UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Gozdecka, M., Meduri, E., Mazan, M., Tzelepis, K., Dudek, M., Knights, A.J., Pardo, M., Yu, L., Choudhary, J.S., Metzakopian, E., Iyer, V., Yun, H., Park, N., Varela, I., Bautista, R., Collord, G., Dovey, O., Garyfallos, D.A., De Braekeleer, E., Kondo, S., Cooper, J., Göttgens, B., Bullinger, L., Northcott, P.A., Adams, D., Vassiliou, G.S. and Huntly, B.J.P.
Nature Genetics 50 (6): 883-894. June 2018

Effects of allelic variations in the human myxovirus resistance protein A on its antiviral activity.
Graf, L., Dick, A., Sendker, F., Barth, E., Marz, M., Daumke, O. and Kochs, G.
Journal of Biological Chemistry 293 (9): 3056-3072. 2 March 2018

Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury.
Gross, A., Pack, L.A.P., Schacht, G.M., Kant, S., Ungewiss, H., Meir, M., Schlegel, N., Preisinger, C., Boor, P., Guldiken, N., Krusche, C.A., Sellge, G., Trautwein, C., Waschke, J., Heuser, A., Leube, R.E. and Strnad, P.
Mucosal Immunology 11 (6): 1630-1639. 1 November 2018

An eicosanoid protects from statin-induced myopathic changes in primary human cells.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
bioRxiv : 271932. 26 February 2018

The CRISPR/Cas9 system sheds new lights on the biology of protozoan parasites.
Grzybek, M., Golonko, A., Górska, A., Szczepaniak, K., Strachecka, A., Lass, A. and Lisowski, P.
Applied Microbiology and Biotechnology 102 (11): 4629-4640. June 2018

Developmental and functional heterogeneity of monocytes.
Guilliams, M., Mildner, A. and Yona, S.
Immunity 49 (4): 595-613. 16 October 2018

Transcriptional and translational differences of microglia from male and female brains.
Guneykaya, D., Ivanov, A., Perez Hernandez, D., Haage, V., Wojtas, B., Meyer, N., Maricos, M., Jordan, P., Buonfiglioli, A., Gielniewski, B., Ochocka, N., Cömert, C., Friedrich, C., Suarez Artiles, L., Kaminska, B., Mertins, P., Beule, D., Kettenmann, H. and Wolf, S.A.
Cell Reports 24 (10): 2773-2783. 4 September 2018

Therapeutic intranasal vaccine HB-ATV-8 prevents atherogenesis and non-alcoholic fatty liver disease in a pig model of atherosclerosis.
Gutiérrez-Vidal, R., Delgado-Coello, B., Méndez-Acevedo, K.M., Calixto-Tlacomulco, S., Damián-Zamacona, S. and Mas-Oliva, J.
Archives of Medical Research 49 (7): 456-470. October 2018

SMARCAD1 haploinsufficiency underlies Huriez syndrome and associated skin cancer susceptibility.
Günther, C., Lee-Kirsch, M.A., Eckhard, J., Matanovic, A., Kerscher, T., Rüschendorf, F., Klein, B., Berndt, N., Zimmermann, N., Flachmeier, C., Thuß, T., Lucas, N., Marenholz, I., Esparza-Gordillo, J., Hübner, N., Traupe, H., Delaporte, E. and Lee, Y.A.
Journal of Investigative Dermatology 138 (6): 1428-1431. June 2018

H

An intrinsic interferon program protects stem cells from viral infection.
Haas, S. and Trumpp, A.
Developmental Cell 44 (3): 279-280. 5 February 2018

Causes and consequences of hematopoietic stem cell heterogeneity.
Haas, S., Trumpp, A. and Milsom, M.D.
Cell Stem Cell 22 (5): 627-638. 3 May 2018

Metabolic barriers to weight gain in patients with anorexia nervosa: a young adult case report.
Haas, V., Stengel, A., Mähler, A., Gerlach, G., Lehmann, C., Boschmann, M., de Zwaan, M. and Herpertz, S.
Frontiers in Psychiatry 9 : 199. May 2018

Impacts of microbiome metabolites on immune regulation and autoimmunity.
Haase, S., Haghikia, A., Wilck, N., Müller, D.N. and Linker, R.A.
Immunology 154 (2): 230-238. June 2018

Faecal microbiota composition associates with abdominal pain in the general population.
Hadizadeh, F., Bonfiglio, F., Belheouane, M., Vallier, M., Sauer, S., Bang, C., Bujanda, L., Andreasson, A., Agreus, L., Engstrand, L., Talley, N.J., Rafter, J., Baines, J.F., Walter, S., Franke, A. and D'Amato, M.
Gut 67 (4): 778-779. 8 March 2018

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors.
Haghverdi, L., Lun, A.T.L., Morgan, M.D. and Marioni, J.C.
Nature Biotechnology 36 (5): 421-427. May 2018

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.
Hammer, Q., Rückert, T., Borst, E.M., Dunst, J., Haubner, A., Durek, P., Heinrich, F., Gasparoni, G., Babic, M., Tomic, A., Pietra, G., Nienen, M., Blau, I.W., Hofmann, J., Na, I.K., Prinz, I., Koenecke, C., Hemmati, P., Babel, N., Arnold, R., Walter, J., Thurley, K., Mashreghi, M.F., Messerle, M. and Romagnani, C.
Nature Immunology 19 (5): 453-463. May 2018

Efficacy of high-frequency repetitive transcranial magnetic stimulation on PANSS factors in schizophrenia with predominant negative symptoms - results from an exploratory re-analysis.
Hansbauer, M., Wobrock, T., Kunze, B., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Cordes, J., Wölwer, W., Winterer, G., Gaebel, W., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Malchow, B., Strube, W., Schneider-Axmann, T., Falkai, P. and Hasan, A.
Psychiatry Research 263 : 22-29. May 2018

Coinheritance of biallelic SLURP1 and SLC39A4 mutations cause a severe genodermatosis with skin peeling and hair loss all over the body.
Harms, F.L., Nampoothiri, S., Kortüm, F., Thomas, J., Panicker, V.V., Alawi, M., Altmüller, J., Yesodharan, D. and Kutsche, K.
British Journal of Dermatology 179 (5): 1192-1194. 1 November 2018

FunImageJ: a lisp framework for scientific image processing.
Harrington, K.I.S., Rueden, C.T. and Eliceiri, K.W.
Bioinformatics 34 (5): 899-900. 1 March 2018

Caveolae link Ca(V)3.2 channels to BK(Ca)-mediated feedback in vascular smooth muscle.
Hashad, A.M., Harraz, O.F., Brett, S.E., Romero, M., Kassmann, M., Puglisi, J.L., Wilson, S.M., Gollasch, M. and Welsh, D.G.
Arteriosclerosis Thrombosis and Vascular Biology 38 (10): 2371-2381. October 2018

Pro-inflammatory monocyte phenotype and cell-specific steroid signaling alterations in unmedicated patients with major depressive disorder.
Hasselmann, H., Gamradt, S., Taenzer, A., Nowacki, J., Zain, R., Patas, K., Ramien, C., Paul, F., Wingenfeld, K., Piber, D., Gold, S.M. and Otte, C.
Frontiers in Immunology 9 : 2693. November 2018

Gene panel testing of 5589 BRCA1/2-negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian Cancer.
Hauke, J., Horvath, J., Groß, E., Gehrig, A., Honisch, E., Hackmann, K., Schmidt, G., Arnold, N., Faust, U., Sutter, C., Hentschel, J., Wang-Gohrke, S., Smogavec, M., Weber, B.H.F., Weber-Lassalle, N., Weber-Lassalle, K., Borde, J., Ernst, C., Altmüller, J., Volk, A.E., Thiele, H., Hübbel, V., Nürnberg, P., Keupp, K., Versmold, B., Pohl, E., Kubisch, C., Grill, S., Paul, V., Herold, N., Lichey, N., Rhiem, K., Ditsch, N., Ruckert, C., Wappenschmidt, B., Auber, B., Rump, A., Niederacher, D., Haaf, T., Ramser, J., Dworniczak, B., Engel, C., Meindl, A., Schmutzler, R.K. and Hahnen, E.
Cancer Medicine 7 (4): 1349-1358. April 2018

NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes.
He, C., Hu, X., Weston, T.A., Jung, R.S., Heizer, P., Tu, Y., Ellison, R., Matsumoto, K., Gerhardt, H., Tontonoz, P., Fong, L.G., Young, S.G. and Jiang, H.
Biochemical and Biophysical Research Communications 504 (4): 899-902. 12 October 2018

Effect of candesartan and metoprolol on myocardial tissue composition during anthracycline treatment: the PRADA trial.
Heck, S.L., Gulati, G., Hoffmann, P., von Knobelsdorff-Brenkenhoff, F., Storås, T.H., Ree, A.H., Gravdehaug, B., Røsjø, H., Steine, K., Geisler, J., Schulz-Menger, J. and Omland, T.
European Heart Journal - Cardiovascular Imaging 19 (5): 544-552. 1 May 2018

Perceptions on the value of bodily functions in multiple sclerosis.
Heesen, C., Haase, R., Melzig, S., Poettgen, J., Berghoff, M., Paul, F., Zettl, U., Marziniak, M., Angstwurm, K., Kern, R., Ziemssen, T. and Stellmann, J.P.
Acta Neurologica Scandinavica 137 (3): 356-362. March 2018

Beyond the limbic system: disruption and functional compensation of large-scale brain networks in patients with anti-LGI1 encephalitis.
Heine, J., Prüss, H., Kopp, U.A., Wegner, F., Then Bergh, F., Münte, T., Wandinger, K.P., Paul, F., Bartsch, T. and Finke, C.
Journal of Neurology Neurosurgery and Psychiatry 89 (11): 1191-1199. November 2018

Preserved heart function after left ventricular pressure overload in adult mice subjected to neonatal cardiac hypoplasia.
Heinecke, K., Heuser, A., Blaschke, F., Jux, C., Thierfelder, L. and Drenckhahn, J.D.
Journal of Developmental Origins of Health and Disease 9 (1): 112-124. February 2018

Emerging functions of DNA transposases and oncogenic mutators in childhood cancer development.
Henssen, A.G. and Kentsis, A.
JCI Insight 3 (20): 123172. 18 October 2018

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia.
Herling, C.D., Abedpour, N., Weiss, J., Schmitt, A., Jachimowicz, R.D., Merkel, O., Cartolano, M., Oberbeck, S., Mayer, P., Berg, V., Thomalla, D., Kutsch, N., Stiefelhagen, M., Cramer, P., Wendtner, C.M., Persigehl, T., Saleh, A., Altmüller, J., Nürnberg, P., Pallasch, C., Achter, V., Lang, U., Eichhorst, B., Castiglione, R., Schäfer, S.C., Büttner, R., Kreuzer, K.A., Reinhardt, H.C., Hallek, M., Frenzel, L.P. and Peifer, M.
Nature Communications 9 (1): 727. 20 February 2018

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice.
Hernandez-Miranda, L.R., Ibrahim, D.M., Ruffault, P.L., Larrosa, M., Balueva, K., Müller, T., de Weerd, W., Stolte-Dijkstra, I., Hostra, R.M.W., Brunet, J.F., Fortin, G., Mundlos, S. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 115 (51): 13021-13026. 18 December 2018

A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.
Hernáez, B., Alonso-Lobo, J.M., Montanuy, I., Fischer, C., Sauer, S., Sigal, L., Sevilla, N. and Alcamí, A.
Nature Communications 9 (1): 5440. 21 December 2018

Erfassung inzidenter kardiovaskulärer und metabolischer Erkrankungen in epidemiologischen Kohortenstudien in Deutschland [Assessing incident cardiovascular and metabolic diseases in epidemiological cohort studies in Germany].
Herrmann, W.J., Weikert, C., Bergmann, M., Boeing, H., Katzke, V.A., Kaaks, R., Tiller, D., Greiser, K.H., Heier, M., Meisinger, C., Schmidt, C.O., Neuhauser, H., Heidemann, C., Jünger, C., Wild, P.S., Schramm, S.H., Jöckel, K.H., Dörr, M. and Pischon, T.
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 61 (4): 420-431. April 2018

Volatile organic compounds in the breath of oral candidiasis patients: a pilot study.
Hertel, M., Schuette, E., Kastner, I., Hartwig, S., Schmidt-Westhausen, A.M., Preissner, R., Paris, S. and Preissner, S.
Clinical Oral Investigations 22 (2): 721-731. March 2018

Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system.
Herz, K., Becker, A., Shi, C., Ema, M., Takahashi, S., Potente, M., Hesse, M., Fleischmann, B.K. and Wenzel, D.
Angiogenesis 21 (2): 349-361. May 2018

PAR-3 controls endothelial planar polarity and vascular inflammation under laminar flow.
Hikita, T., Mirzapourshafiyi, F., Barbacena, P., Riddell, M., Pasha, A., Li, M., Kawamura, T., Brandes, R.P., Hirose, T., Ohno, S., Gerhardt, H., Matsuda, M., Franco, C.A. and Nakayama, M.
EMBO Reports 19 (9): e45253. 1 September 2018

Embryos and embryonic stem cells from the white rhinoceros.
Hildebrandt, T.B., Hermes, R., Colleoni, S., Diecke, S., Holtze, S., Renfree, M.B., Stejskal, J., Hayashi, K., Drukker, M., Loi, P., Göritz, F., Lazzari, G. and Galli, C.
Nature Communications 9 (1): 2589. 4 July 2018

GRHL2 is required for collecting duct epithelial barrier function and renal osmoregulation.
Hinze, C., Ruffert, J., Walentin, K., Himmerkus, N., Nikpey, E., Tenstad, O., Wiig, H., Mutig, K., Yurtdas, Z.Y., Klein, J.D., Sands, J.M., Branchi, F., Schumann, M., Bachmann, S., Bleich, M. and Schmidt-Ott, K.M.
Journal of the American Society of Nephrology 29 (3): 857-868. March 2018

Expanding the map of protein-RNA interaction sites via cell fusion followed by PAR-CLIP.
Hinze, F., Drewe-Boss, P., Milek, M., Ohler, U., Landthaler, M. and Gotthardt, M.
RNA Biology 15 (3): 359-368. 4 March 2018

Unraveling the transcriptional regulation of TWIST1 in limb development.
Hirsch, N., Eshel, R., Bar Yaacov, R., Shahar, T., Shmulevich, F., Dahan, I., Levaot, N., Kaplan, T., Lupiáñez, D.G. and Birnbaum, R..
PLoS Genetics 14 (10): e1007738. 29 October 2018

Nontargeted identification of tracer incorporation in high-resolution mass spectrometry.
Hoffmann, F., Jaeger, C., Bhattacharya, A., Schmitt, C.A. and Lisec, J.
Analytical Chemistry 90 (12): 7253-7260. 19 June 2018

Efficient non-viral gene delivery into human hematopoietic stem cells by minicircle Sleeping Beauty transposon vectors.
Holstein, M., Mesa-Nuñez, C., Miskey, C., Almarza, E., Poletti, V., Schmeer, M., Grueso, E., Ordóñez Flores, J.C., Kobelt, D., Walther, W., Aneja, M.K., Geiger, J,, Bonig, H.B., Izsvák, Z., Schleef, M., Rudolph, C., Mavilio, F., Bueren, J.A., Guenechea, G. and Ivics, Z.
Molecular Therapy 26 (4): 1137-1153. 4 April 2018

Multisite de novo mutations in human offspring after paternal exposure to ionizing radiation.
Holtgrewe, M., Knaus, A., Hildebrand, G., Pantel, J.T., de los Santos, M.R., Neveling, K., Goldmann, J., Schubach, M., Jäger, M., Coutelier, M., Mundlos, S., Beule, D., Sperling, K. and Krawitz, P.M.
Scientific Reports 8 (1): 14611. 2 October 2018

A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety.
Hommers, L.G., Richter, J., Yang, Y., Raab, A., Baumann, C., Lang, K., Schiele, M.A., Weber, H., Wittmann, A., Wolf, C., Alpers, G.W., Arolt, V., Domschke, K., Fehm, L., Fydrich, T., Gerlach, A., Gloster, A.T., Hamm, A.O., Helbig-Lang, S., Kircher, T., Lang, T., Pané-Farré, C.A., Pauli, P., Pfleiderer, B., Reif, A., Romanos, M., Straube, B., Ströhle, A., Wittchen, H.U., Frantz, S., Ertl, G., Lohse, M.J., Lueken, U. and Deckert, J.
Translational Psychiatry 8 (1): 226. 19 October 2018

Genetic deletion of the Angiotensin-(1-7) receptor Mas leads a reduced ovulatory rate.
Honorato-Sampaio, K., Ferreira Andrade, R., Bader, M., de Souza Martins, A., Souza Santos, R.A. and Reis, A.M.
Peptides 107 : 83-88. September 2018

Oncogene-specific T cells fail to eradicate lymphoma-initiating B cells in mice.
Hoser, D., Schön, C., Loddenkemper, C., Lohneis, P., Kühl, A.A., Sommermann, T., Blankenstein, T. and Willimsky, G.
Blood 132 (9): 924-934. 30 August 2018

Myocardial effective transverse relaxation time T(2)* is elevated in hypertrophic cardiomyopathy: a 7.0 T magnetic resonance imaging study.
Huelnhagen, T., Ku, M.C., Reimann, H.M., Serradas Duarte, T., Pohlmann, A., Flemming, B., Seeliger, E., Eichhorn, C., Ferrari, V.A., Prothmann, M., Schulz-Menger, J. and Niendorf, T.
Scientific Reports 8 (1): 3974. 5 March 2018

Quantification of myocardial effective transverse relaxation time with magnetic resonance at 7.0 tesla for a better understanding of myocardial (patho)physiology.
Huelnhagen, T., Serradas-Duarte, Teresa, Hezel, Fabian, Paul, K. and Niendorf, T.
In: Quantification of Biophysical Parameters in Medical Imaging. Springer, Cham, Switzerland, 343-372. ISBN 978-3-319-65923-7 2018

Duration of storage influences the hemoglobin rising effect of red blood cells in patients undergoing major abdominal surgery.
Hunsicker, O., Hessler, K., Krannich, A., Boemke, W., Braicu, I., Sehouli, J., Meyer, O., Pruß, A., Spies, C. and Feldheiser, A.
Transfusion 58 (8): 1870-1880. August 2018

Development of clinical simultaneous SPECT/MRI.
Hutton, B.F., Occhipinti, M., Kuehne, A., Máthé, D., Kovács, N., Waiczies, H., Erlandsson, K., Salvado, D., Carminati, M., Montagnani, G., Short, S., Ottobrini, L., van Mullekom, P., Piemonte, C., Bukki, T., Nyitrai, Z., Papp, Z., Nagy, K., Niendorf, T., de Francesco, I. and Fiorini, C.
British Journal of Radiology 91 (1081): 20160690. January 2018

Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: Comparison to chronic phencyclidine and MK-801.
Hámor, P.U., Šírová, J., Páleníček, T., Zaniewska, M., Bubeníková-Valešová, V. and Schwendt, M.
Pharmacology Biochemistry and Behavior 175 : 89-100. December 2018

Bacterial RNA biology on a genome scale.
Hör, J., Gorski, S.A. and Vogel, J.
Molecular Cell 70 (5): 785-799. 7 June 2018

I

Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy.
Iannotti, F.A., Pagano, E., Guardiola, O., Adinolfi, S., Saccone, V., Consalvi, S., Piscitelli, F., Gazzerro, E., Busetto, G., Carrella, D., Capasso, R., Puri, P.L., Minchiotti, G. and Di Marzo, V.
Nature Communications 9 (1): 3950. 27 September 2018

Determinants of promoter and enhancer transcription directionality in metazoans.
Ibrahim, M.M., Karabacak, A., Glahs, A., Kolundzic, E., Hirsekorn, A., Carda, A., Tursun, B., Zinzen, R.P., Lacadie, S.A. and Ohler, U.
Nature Communications 9 (1): 4472. 26 October 2018

Microbiome and diseases: colorectal cancer.
Iftekhar, A., Sperlich, A., Janssen, K.P. and Sigal, M.
In: The Gut Microbiome in Health and Disease. Springer, Cham, 231-249. ISBN 978-3-319-90544-0 2018

Effects of carvedilol versus metoprolol on platelet aggregation in patients with acute coronary syndrome: the PLATE-BLOCK study.
Ilardi, F., Gargiulo, G., Schiattarella, G.G., Giugliano, G., Paolillo, R., Menafra, G., De Angelis, E., Scudiero, L., Franzone, A., Stabile, E., Perrino, C., Cirillo, P., Morisco, C., Izzo, R., Trimarco, V. and Esposito, G.
American Journal of Cardiology 122 (1): 6-11. 1 July 2018

Phosphorylation of the ribosomal protein RPL12/uL11 affects translation during mitosis.
Imami, K., Milek, M., Bogdanow, B., Yasuda, T., Kastelic, N., Zauber, H., Ishihama, Y., Landthaler, M. and Selbach, M.
Molecular Cell 72 (1): 84-98. 4 October 2018

Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: a comprehensive examination of the potential carriers for semiochemicals.
Iovinella, I., McAfee, A., Mastrobuoni, G., Kempa, S., Foster, L.J., Pelosi, P. and Dani, F.R.
Journal of Proteomics 181 : 131-141. 15 June 2018

Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations.
Irmak, D., Fatima, A., Gutiérrez-Garcia, R., Rinschen, M.M., Wagle, P., Altmüller, J., Arrigoni, L., Hummel, B., Klein, C., Frese, C.K., Sawarkar, R., Rada-Iglesias, A. and Vilchez, D.
Human Molecular Genetics 27 (23): 4117-4134. 1 December 2018

J

Rare gene deletions in genetic generalized and Rolandic epilepsies.
Jabbari, K., Bobbili, D.R., Lal, D., Reinthaler, E.M., Schubert, J., Wolking, S., Sinha, V., Motameny, S., Thiele, H., Kawalia, A., Altmüller, J., Toliat, M.R., Kraaij, R., van Rooij, J., Uitterlinden, A.G., Ikram, M.A., Zara, F., Lehesjoki, A.E., Krause, R., Zimprich, F., Sander, T., Neubauer, B.A., May, P., Lerche, H. and Nürnberg, P.
PLoS ONE 13 (8): e0202022. 27 August 2018

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.
Jacquelin, S., Straube, J., Cooper, L., Vu, T., Song, A., Bywater, M., Baxter, E., Heidecker, M., Wackrow, B., Porter, A., Ling, V., Green, J., Austin, R., Kazakoff, S., Waddell, N., Hesson, L.B., Pimanda, J.E., Stegelmann, F., Bullinger, L., Döhner, K., Rampal, R.K., Heckl, D., Hill, G.R. and Lane, S.W.
Blood 132 (26): 2707-2721. 27 December 2018

Human mesenchymal factors induce rat hippocampal- and human neural stem cell dependent oligodendrogenesis.
Jadasz, J.J., Tepe, L., Beyer, F., Samper Agrelo, I., Akkermann, R., Spitzhorn, L.S., Silva, M.E., Oreffo, R.O.C., Hartung, H.P., Prigione, A., Rivera, F.J., Adjaye, J. and Kuery, P.
Glia 66 (1): 145-160. January 2018

Variability and reliability study of overall physical activity and activity intensity levels using 24 h-accelerometry-assessed data.
Jaeschke, L., Steinbrecher, A., Jeran, S., Konigorski, S. and Pischon, T.
BMC Public Health 18 (1): 530. 20 April 2018

Characterization of hyperbranched core-multishell nanocarriers as an innovative drug delivery system for the application at the oral mucosa.
Jager, J., Obst, K., Lohan, S.B., Viktorov, J., Staufenbiel, S., Renz, H., Unbehauen, M., Haag, R., Hedtrich, S., Teutloff, C., Meinke, M..C., Danker, K. and Dommisch, H.
Journal of periodontal research 53 (1): 57-65. February 2018

MOG-Enzephalomyelitis: Internationale Empfehlungen zu Diagnose und Antikörpertestung [MOG encephalomyelitis: international recommendations on diagnosis and antibody testing].
Jarius, S., Paul, F., Aktas, O., Asgari, N., Dale, R.C., de Seze, J., Franciotta, D., Fujihara, K., Jacob, A., Kim, H.J., Kleiter, I., Kümpfel, T., Levy, M., Palace, J., Ruprecht, K., Saiz, A., Trebst, C., Weinshenker, B.G. and Wildemann, B.
Nervenarzt 89 (12): 1388-1399. December 2018

MOG encephalomyelitis: international recommendations on diagnosis and antibody testing.
Jarius, S., Paul, F., Aktas, O., Asgari, N., Dale, R.C., de Seze, J., Franciotta, D., Fujihara, K., Jacob, A., Kim, H.J., Kleiter, I., Kümpfel, T., Levy, M., Palace, J., Ruprecht, K., Saiz, A., Trebst, C., Weinshenker, B.G. and Wildemann, B.
Journal of Neuroinflammation 15 (1): 134. 3 May 2018

MOG-IgG in primary and secondary chronic progressive multiple sclerosis: a multicenter study of 200 patients and review of the literature.
Jarius, S., Ruprecht, K., Stellmann, J.P., Huss, A., Ayzenberg, I., Willing, A., Trebst, C., Pawlitzki, M., Abdelhak, A., Grüter, T., Leypoldt, F., Haas, J., Kleiter, I., Tumani, H., Fechner, K., Reindl, M., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 15 (1): 88. 19 March 2018

Baló's concentric sclerosis is immunologically distinct from multiple sclerosis: results from retrospective analysis of almost 150 lumbar punctures.
Jarius, S., Würthwein, C., Behrens, J.R., Wanner, J., Haas, J., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 15 (1): 22. 18 January 2018

Bevacizumab in temozolomide refractory high-grade gliomas: single-centre experience and review of the literature.
Jeck, J., Kassubek, R., Coburger, J., Edenhofer, S., Schönsteiner, S.S., Ludolph, A.C., Schmitz, B., Engelke, J., Mayer-Steinacker, R., Lewerenz, J. and Bullinger, L.
Therapeutic Advances in Neurological Disorders 11 : 1756285617753597. 21 January 2018

CLC chloride channels and transporters: structure, function, physiology, and disease.
Jentsch, T.J. and Pusch, M.
Physiological Reviews 98 (3): 1493-1590. July 2018

High peak and high average radiofrequency power transmit/receive switch for thermal magnetic resonance.
Ji, Y., Hoffmann, W., Pham, M., Dunn, A.E., Han, H., Özerdem, C., Waiczies, H., Rohloff, M., Endemann, B., Boyer, C., Lim, M., Niendorf, T. and Winter, L.
Magnetic Resonance in Medicine 80 (5): 2246-2255. November 2018

Can we end the salt wars with a randomized clinical trial in a controlled environment?
Jones, D.W., Luft, F.C., Whelton, P.K., Alderman, M.H., Hall, J.E., Peterson, E.D., Califf, R.M. and McCarron, D.A.
Hypertension 72 (1): 10-11. July 2018

Gut microbiota composition is associated with environmental landscape in honey bees.
Jones, J.C., Fruciano, C., Hildebrand, F., Al Toufalilia, H., Balfour, N.J., Bork, P., Engel, P., Ratnieks, F.L.W. and Hughes, W.O.H.
Ecology and Evolution 8 (1): 441-451. January 2018

The gut microbiome is associated with behavioural task in honey bees.
Jones, J.C., Fruciano, C., Marchant, J., Hildebrand, F., Forslund, S., Bork, P., Engel, P. and Hughes, W.O.H.
Insectes Sociaux 65 (3): 419-429. August 2018

Long noncoding RNA lISPR1 is required for S1P signaling and endothelial cell function.
Josipovic, I., Pflueger, B., Fork, C., Vasconez, A.E., Oo, J.A., Hitzel, J., Seredinski, S., Gamen, E., Heringdorf, D.M.Z., Chen, W., Looso, M., Pullamsetti, S.S., Brandes, R.P. and Leisegang, M.S.
Journal of Molecular and Cellular Cardiology 116 : 57-68. March 2018

Single synaptic inputs drive high-precision action potentials in parvalbumin expressing GABA-ergic cortical neurons in vivo.
Jouhanneau, J.S., Kremkow, J. and Poulet, J.F.A.
Nature Communications 9 (1): 1540. 18 April 2018

K(2P) TASK-2 and KCNQ1/KCNE3 K(+) channels are major players contributing to intestinal anion and fluid secretion.
Julio-Kalajzić, F., Villanueva, S., Burgos, J., Ojeda, M., Cid, L.P., Jentsch, T.J. and Sepúlveda, F.V.
Journal of Physiology 596 (3): 393-407. 1 February 2018

Crystal structures of the single PDZ domains from GRASP65 and their interaction with the golgin GM130.
Jurk, C.M., Roske, Y. and Heinemann, U.
Croatica Chemica Acta 91 (2): 255-264. June 2018

Chromatin accessibility dynamics across C. elegans development and ageing.
Jänes, J., Dong, Y., Schoof, M., Serizay, J., Appert, A., Cerrato, C., Woodbury, C., Chen, R., Gemma, C., Huang, N., Kissiov, D., Stempor, P., Steward, A., Zeiser, E., Sauer, S. and Ahringer, J.
eLife 7 : e37344. 26 October 2018

Agonistic autoantibodies to the β2-adrenergic receptor involved in the pathogenesis of open-angle glaucoma.
Jünemann, A., Hohberger, B., Rech, J., Sheriff, A., Fu, Q., Schlötzer-Schrehardt, U., Voll, R.E., Bartel, S., Kalbacher, H., Hoebeke, J., Rejdak, R., Horn, F., Wallukat, G., Kunze, R. and Herrmann, M.
Frontiers in Immunology 9 : 145. 12 February 2018

K

Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.
Kabrani, E., Chu, V.T., Tasouri, E., Sommermann, T., Baßler, K., Ulas, T., Zenz, T., Bullinger, L., Schultze, J.L., Rajewsky, K. and Sander, S.
Blood 132 (25): 2670-2683. 20 December 2018

PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells.
Kahn, J.D., Miller, P.G., Silver, A.J., Sellar, R.S., Bhatt, S., Gibson, C., McConkey, M., Adams, D., Mar, B., Mertins, P., Fereshetian, S., Krug, K., Zhu, H., Letai, A., Carr, S.A., Doench, J., Jaiswal, S. and Ebert, B.L.
Blood 132 (11): 1095-1105. 13 September 2018

The influence of capsaicin on the integrity of microvascular endothelial cell monolayers.
Kaiser, M., Burek, M., Britz, S., Lankamp, F., Ketelhut, S., Kemper, B., Förster, C., Gorzelanny, C. and Goycoolea, F.M.
International Journal of Molecular Sciences 20 (1): 122. 30 December 2018

OR2H2 regulates the differentiation of human myoblast cells by its ligand aldehyde 13-13.
Kalbe, B., Osterloh, M., Schulz, V.M., Altmüller, J., Becker, C., Osterloh, S. and Hatt, H.
Archives of Biochemistry and Biophysics 645 : 72-80. 1 May 2018

Letter to the Editor: Influence of rTMS on smoking in patients with schizophrenia.
Kamp, D., Engelke, C., Wobrock, T., Kunze, B., Wölwer, W., Winterer, G., Schmidt-Kraepelin, C., Gaebel, W., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Raees, A., Honer, W.G., Malchow, B., Schneider-Axmann, T., Falkai, P., Hasan, A. and Cordes, J.
Schizophrenia Research 192 : 481-484. February 2018

A novel RNA editing sensor tool and a specific agonist determine neuronal protein expression of RNA-edited glycine receptors and identify a genomic APOBEC1 dimorphism as a new genetic risk factor of epilepsy.
Kankowski, S., Förstera, B., Winkelmann, A., Knauff, P., Wanker, E.E., You, X.A., Semtner, M., Hetsch, F. and Meier, J.C.
Frontiers in Molecular Neuroscience 10 : 439. 11 January 2018

Mast cells and serotonin synthesis modulate Chagas disease in the colon: clinical and experimental evidence.
Kannen, V., Sakita, J.Y., Carneiro, Z.A., Bader, M., Alenina, N., Teixeira, R.R., de Oliveira, E.C., Brunaldi, M.O., Gasparotto, B., Sartori, D.C., Fernandes, C.R., Silva, J.S., Andrade, M.V., Silva, W.A., Uyemura, S.A. and Garcia, S.B.
Digestive Diseases and Sciences 63 (6): 1473-1484. June 2018

The association between brain volume, cortical brain infarcts, and physical frailty.
Kant, I.M.J., de Bresser, J., van Montfort, S.J.T., Aarts, E., Verlaan, J.J., Zacharias, N., Winterer, G., Spies, C., Slooter, A.J.C. and Hendrikse, J.
Neurobiology of Aging 70 : 247-253. October 2018

A hybrid quantum-classical modeling approach for electrically driven quantum light sources.
Kantner, M., Mittnenzweig, M. and Koprucki, T.
In: Physics and Simulation of Optoelectronic Devices XXVI, 27 Jan - 01 Feb 2018, San Francisco, CA, USA. 23 February 2018

A single-cell transcriptome atlas of the mouse glomerulus.
Karaiskos, N., Rahmatollahi, M., Boltengagen, A., Liu, H., Hoehne, M., Rinschen, M., Schermer, B., Benzing, T., Rajewsky, N., Kocks, C., Kann, M. and Müller, R.U.
Journal of the American Society of Nephrology 29 (8): 2060-2068. August 2018

Neuro-Behcet's disease in a patient with thrombotic thrombocytopenic purpura.
Karaivanov, S., Krueger, A., Bethke, N., Radbruch, H., Eckardt, K.U. and Schreiber, A.
Rheumatology 57 (6): 1117-1118. 1 June 2018

Targeted sequencing with expanded gene profile enables high diagnostic yield in non-5q-spinal muscular atrophies.
Karakaya, M., Storbeck, M., Strathmann, E.A., Delle Vedove, A., Hölker, I., Altmueller, J., Naghiyeva, L., Schmitz-Steinkrüger, L., Vezyroglou, K., Motameny, S., Alawbathani, S., Thiele, H., Polat, A.I., Okur, D., Boostani, R., Karimiani, E.G., Wunderlich, G., Ardicli, D., Topaloglu, H., Kirschner, J., Schrank, B., Maroofian, R., Magnusson, O., Yis, U., Nürnberg, P., Heller, R. and Wirth, B.
Human Mutation 39 (9): 1284-1298. September 2018

Role of alpha1-adrenergic receptor antibodies in Alzheimer's disease.
Karczewski, P., Hempel, P. and Bimmler, M.
Frontiers in Bioscience 23 : 2082-2089. 1 June 2018

High-salt diet causes expansion of the lymphatic network and increased lymph flow in skin and muscle of rats.
Karlsen, T.V., Nikpey, E., Han, J., Reikvam, T., Rakova, N., Castorena-Gonzalez, J.A., Davis, M.J., Titze, J.M., Tenstad, O. and Wiig, H.
Arteriosclerosis Thrombosis and Vascular Biology 38 (9): 2054-2064. September 2018

Whole exome sequencing identifies a mutation in EYA1 and GLI3 in a patient with branchio‑otic syndrome and esophageal atresia: Coincidence or a digenic mode of inheritance?
Kause, F., Reutter, H., Marsch, F., Thiele, H., Altmüller, J., Ludwig, M. and Zhang, R.
Molecular Medicine Reports 17 (2): 3200-3205. February 2018

Nuclear pore complex components in the malaria parasite Plasmodium berghei.
Kehrer, J., Kuss, C., Andres-Pons, A., Reustle, A., Dahan, N., Devos, D., Kudryashev, M., Beck, M., Mair, G.R. and Frischknecht, F.
Scientific Reports 8 (1): 11249. 26 July 2018

Diverging roads to the heart.
Kelly, R.G. and Sperling, S.R.
Science 359 (6380): 1098-1099. 9 March 2018

Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis.
Khajuria, R.K., Munschauer, M., Ulirsch, J.C., Fiorini, C., Ludwig, L.S., McFarland, S.K., Abdulhay, N.J., Specht, H., Keshishian, H., Mani, D.R., Jovanovic, M., Ellis, S.R., Fulco, C.P., Engreitz, J.M., Schütz, S., Lian, J., Gripp, K.W., Weinberg, O.K., Pinkus, G.S., Gehrke, L., Regev, A., Lander, E.S., Gazda, H.T., Lee, W.Y., Panse, V.G., Carr, S.A. and Sankaran, V.G.
Cell 173 (1): 90-103. 22 March 2018

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.
Kim, M., Wende, H., Walcher, J., Kühnemund, J., Cheret, C., Kempa, S., McShane, E., Selbach, M., Lewin, G.R. and Birchmeier, C.
Genes & Development 32 (9-10): 645-657. 10 May 2018

Guidelines for training in cardiovascular magnetic resonance (CMR).
Kim, R.J., Simonetti, O.P., Westwood, M., Kramer, C.M., Narang, A., Friedrich, M.G., Powell, A.J., Carr, J.C., Schulz-Menger, J., Nagel, E., Chan, W.S., Bremerich, J., Ordovas, K.G., Rollings, R.C., Patel, A.R. and Ferrari, V.A.
Journal of Cardiovascular Magnetic Resonance 20 (1): 57. 16 August 2018

Racial differences in neuromyelitis optica spectrum disorder.
Kim, S.H., Mealy, M.A., Levy, M., Schmidt, F., Ruprecht, K., Paul, F., Ringelstein, M., Aktas, O., Hartung, H.P., Asgari, N., Tsz-Ching, J.L., Siritho, S., Prayoonwiwat, N., Shin, H.J., Hyun, J.W., Han, M., Leite, M.I., Palace, J. and Kim, H.J.
Neurology 91 (22): e2089-e2099. 27 November 2018

Preanalytical processing and biobanking procedures of biological samples for metabolomics research: a white paper, community perspective (for "Precision Medicine and Pharmacometabolomics Task Group"-The Metabolomics Society Initiative).
Kirwan, J.A., Brennan, L., Broadhurst, D., Fiehn, O., Cascante, M., Dunn, W.B., Schmidt, M.A. and Velagapudi, V.
Clinical Chemistry 64 (8): 1158-1182. August 2018

Use of a sequential high throughput screening assay to identify novel inhibitors of the eukaryotic SRP-Sec61 targeting/translocation pathway.
Klein, W., Rutz, C., Eckhard, J., Provinciael, B., Specker, E., Neuenschwander, M., Kleinau, G., Scheerer, P., von Kries, J.P., Nazaré, M., Vermeire, K. and Schülein, R.
PLoS ONE 13 (12): e0208641. 13 December 2018

S1P signalling differentially affects migration of peritoneal B cell populations in vitro and influences the production of intestinal IgA in vivo.
Kleinwort, A., Luehrs, F., Heidecke, C.D., Lipp, M. and Schulze, T.
International Journal of Molecular Sciences 19 (2): 391. 29 January 2018

Apheresis therapies for NMOSD attacks: a retrospective study of 207 therapeutic interventions.
Kleiter, I., Gahlen, A., Borisow, N., Fischer, K., Wernecke, K.D., Hellwig, K., Pache, F., Ruprecht, K., Havla, J., Kümpfel, T., Aktas, O., Hartung, H.P., Ringelstein, M., Geis, C., Kleinschnitz, C., Berthele, A., Hemmer, B., Angstwurm, K., Stellmann, J.P., Schuster, S., Stangel, M., Lauda, F., Tumani, H., Mayer, C., Krumbholz, M., Zeltner, L., Ziemann, U., Linker, R., Schwab, M., Marziniak, M., Then Bergh, F., Hofstadt-van Oy, U., Neuhaus, O., Zettl, U.K., Faiss, J., Wildemann, B., Paul, F., Jarius, S. and Trebst, C.
Neurology Neuroimmunology & Neuroinflammation 5 (6): e504. November 2018

Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response.
Klempin, F., Mosienko, V., Matthes, S., Villela, D.C., Todiras, M., Penninger, J.M., Bader, M., Santos, R.A.S. and Alenina, N.
Cellular and Molecular Life Sciences 75 (19): 3625-3634. October 2018

Normobaric hypoxic conditioning in men with metabolic syndrome.
Klug, L., Mähler, A., Rakova, N., Mai, K., Schulz-Menger, J., Rahn, G., Busjahn, A., Jordan, J., Boschmann, M. and Luft, F.C.
Physiological Reports 6 (24): e13949. December 2018

Oral administration of a novel lipophilic PPARδ agonist is not neuroprotective after rodent cerebral ischemia.
Knauss, S., Endres, M., Blaschke, F., Hindinger, C. and Kunz, A.
Journal of Cerebral Blood Flow and Metabolism 38 (1): 174-185. 1 January 2018

Mutant Plasticity Related Gene 1 (PRG1) acts as a potential modifier in SCN1A related epilepsy.
Knierim, E., Vogt, J., Kintscher, M., Ponomarenko, A., Baumgart, J., Sanker Beed, P., Korotkova, T., Trimbuch, T., Panzer, A., Stephani, U., Escayg, A., Lerche, H., Nitsch, R., Schmitz, D. and Schuelke, M.
bioRxiv : 282871. 15 March 2018

Structural investigation of glycan recognition by the ERAD quality control lectin Yos9.
Kniss, A., Kazemi, S., Löhr, F., Berger, M., Rogov, V.V., Güntert, P., Sommer, T., Jarosch, E. and Dötsch, V.
Journal of Biomolecular NMR 72 (1-2): 1-10. October 2018

Chain assembly and disassembly processes differently affect the conformational space of ubiquitin chains.
Kniss, A., Schuetz, D., Kazemi, S., Pluska, L., Spindler, P.E., Rogov, V.V., Husnjak, K., Dikic, I., Güntert, P., Sommer, T., Prisner, T.F. and Dötsch, V.
Structure 26 (2): 249-258. 6 February 2018

Single-molecule fluorescence in situ hybridization (FISH) of circular RNA CDR1as.
Kocks, C., Boltengagen, A., Piwecka, M., Rybak-Wolf, A. and Rajewsky, N.
Methods in Molecular Biology 1724 : 77-96. 2018

FACT sets a barrier for cell fate reprogramming in Caenorhabditis elegans and human cells.
Kolundzic, E., Ofenbauer, A., Bulut, S.I., Uyar, B., Baytek, G., Sommermeier, A., Seelk, S., He, M., Hirsekorn, A., Vucicevic, D., Akalin, A., Diecke, S., Lacadie, S.A. and Tursun, B.
Developmental Cell 46 (5): 611-626. 10 September 2018

Application of RNAi and heat-shock-induced transcription factor expression to reprogram germ cells to neurons in C. elegans.
Kolundzic, E., Seelk, S. and Tursun, B.
Journal of Visualized Experiments (131): e56889. 1 January 2018

Estimating and testing direct genetic effects in directed acyclic graphs using estimating equations.
Konigorski, S., Wang, Y., Cigsar, C. and Yilmaz, Y.E.
Genetic Epidemiology 42 (2): 174-186. March 2018

Autologous iPSC-based vaccines elicit anti-tumor responses in vivo.
Kooreman, N.G., Kim, Y., de Almeida, P.E., Termglinchan, V., Diecke, S., Shao, N.Y., Wei, T.T., Yi, H., Dey, De., Nelakanti, R., Brouwer, T.P., Paik, D.T., Sagiv-Barfi, I., Han, A., Quax, P.H.A., Hamming, J.F., Levy, R., Davis, M.M. and Wu, J.C.
Cell Stem Cell 22 (4): 501-513. 5 April 2018

Elevated tissue sodium deposition in patients with type 2 diabetes on hemodialysis detected by (23)Na magnetic resonance imaging.
Kopp, C., Linz, P., Maier, C., Wabel, P., Hammon, M., Nagel, A.M., Rosenhauer, D., Horn, S., Uder, M., Luft, F.C., Titze, J. and Dahlmann, A.
Kidney International 93 (5): 1191-1197. May 2018

Loss of pten and activation of kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice.
Kopp, J.L., Dubois, C.L., Schaeffer, D.F., Samani, A., Taghizadeh, F., Cowan, R.W., Rhim, A.D., Stiles, B.L., Valasek, M. and Sander, M.
Gastroenterology 154 (5): 1509-1523.e5. April 2018

Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - The THYROID Project.
Kopp, S., Krüger, M., Feldmann, S., Oltmann, H., Schütte, A., Schmitz, B., Bauer, J., Schulz, H., Saar, K., Hübner, N., Wehland, M., Nassef, M.Z., Melnik, D., Meltendorf, S., Infanger, M. and Grimm, D.
Scientific Reports 8 (1): 10355. 9 July 2018

The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine.
Kopp, S., Sahana, J., Islam, T., Petersen, A.G., Bauer, J., Corydon, T.J., Schulz, H., Saar, K., Huebner, N., Slumstrup, L., Riwaldt, S., Wehland, M., Infanger, M., Luetzenberg, R. and Grimm, D.
Scientific Reports 8 (1): 921. 17 January 2018

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.
Koren, E., Yosefzon, Y., Ankawa, R., Soteriou, D., Jacob, A., Nevelsky, A., Ben-Yosef, R., Bar-Sela, G. and Fuchs, Y.
Nature Communications 9 (1): 4582. 2 November 2018

Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease.
Kork, F., Jankowski, J., Goswami, A., Weis, J., Brook, G., Yamoah, A., Anink, J., Aronica, E., Fritz, S., Huck, C., Schipke, C., Peters, O., Tepel, M., Noels, H. and Jankowski, V.
Neurology 91 (19): e1799-e1808. 6 November 2018

Therapeutic targeting of cathepsin C: from pathophysiology to treatment.
Korkmaz, B., Caughey, G.H., Chapple, I., Gauthier, F., Hirschfeld, J., Jenne, D.E., Kettritz, R., Lalmanach, G., Lamort, A.S., Lauritzen, C., Legowska, M., Lesner, A., Marchand-Adam, S., McKaig, S.J., Moss, C., Pedersen, J., Roberts, H., Schreiber, A., Seren, S. and Thakkar, N.S.
Pharmacology & Therapeutics 190 : 202-236. October 2018

Selective maternal seeding and environment shape the human gut microbiome.
Korpela, K., Costea, P., Coelho, L.P., Kandels-Lewis, S., Willemsen, G., Boomsma, D.I., Segata, N. and Bork, P.
Genome Research 28 (4): 561-568. April 2018

Predicting response to repetitive transcranial magnetic stimulation in patients with schizophrenia using structural magnetic resonance imaging: a multisite machine learning analysis.
Koutsouleris, N., Wobrock, T., Guse, B., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Cordes, J., Woelwer, W., Musso, F., Winterer, G., Gaebel, W., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Dwyer, D., Ghaseminejad, F., Dechent, P., Malchow, B., Kreuzer, P.M., Poeppl, T.B., Schneider-Axmann, T., Falkai, P. and Hasan, A.
Schizophrenia Bulletin 44 (5): 1021-1034. 20 August 2018

MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
Kozlowski, M., Corujo, D., Hothorn, M., Guberovic, I., Mandemaker, I.K., Blessing, C., Sporn, J., Gutierrez-Triana, A., Smith, R., Portmann, T., Treier, M., Scheffzek, K., Huet, S., Timinszky, G., Buschbeck, M. and Ladurner, A.G.
EMBO Reports 19 (10): e44445. 1 October 2018

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis.
Kragesteen, B.K., Spielmann, M., Paliou, C., Heinrich, V., Schöpflin, R., Esposito, A., Annunziatella, C., Bianco, S., Chiariello, A.M., Jerković, I., Harabula, I., Guckelberger, P., Pechstein, M., Wittler, L., Chan, Wi.L., Franke, M., Lupiáñez, D.G., Kraft, K., Timmermann, B., Vingron, M., Visel, A., Nicodemi, M., Mundlos, S. and Andrey, G.
Nature Genetics 50 (10): 1463-1473. October 2018

Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas.
Kratzsch, T., Kuhn, S.A., Joedicke, A., Hanisch, U.K., Vajkoczy, P., Hoffmann, J. and Fichtner, I.
Journal of Cancer Research and Clinical Oncology 144 (5): 809-819. May 2018

The role of PAR1 autoantibodies in patients with primary epithelial ovarian cancer.
Kreienbring, K., Franz, A., Richter, R., Dragun, D., Heidecke, H., Müller, D., Mentze, M., Dechend, R., Sehouli, J. and Braicu, E.I.
Anticancer Research 38 (6): 3619-3625. June 2018

NF-κB participates in mouse hair cycle control and plays distinct roles in the various pelage hair follicle types.
Krieger, K., Millar, S.E., Mikuda, N., Krahn, I., Kloepper, J.E., Bertolini, M., Scheidereit, C., Paus, R. and Schmidt-Ullrich, R.
Journal of Investigative Dermatology 138 (2): 256-264. February 2018

Brain serotonin critically contributes to the biological effects of electroconvulsive seizures.
Kronenberg, G., Petermann, M., Dormann, C., Bader, M., Gass, P., Hellweg, R. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 268 (8): 861-864. December 2018

Distinguishing features of microglia- and monocyte-derived macrophages after stroke.
Kronenberg, G., Uhlemann, R., Richter, N., Klempin, F., Wegner, S., Staerck, L., Wolf, S., Uckert, W., Kettenmann, H., Endres, M. and Gertz, K.
Acta Neuropathologica 135 (4): 551. April 2018

Cardiac MRI in small animals.
Ku, M.C., Huelnhagen, T., Niendorf, T. and Pohlmann, A.
Methods in Molecular Biology 1718 : 269-284. 2018

Assessment of blood brain barrier leakage with gadolinium-enhanced MRI.
Ku, M.C., Waiczies, S., Niendorf, T. and Pohlmann, A.
Methods in Molecular Biology 1718 : 395-408. 2018

Comparison of probabilistic tractography and tract-based spatial statistics for assessing optic radiation damage in patients with autoimmune inflammatory disorders of the central nervous system.
Kuchling, J., Backner, Y., Oertel, F.C., Raz, N., Bellmann-Strobl, J., Ruprecht, K., Paul, F., Levin, N., Brandt, A.U. and Scheel, M.
NeuroImage: Clinical 19 : 538-550. 8 May 2018

Nrf2-mediated antioxidant defense and peroxiredoxin 6 are linked to biosynthesis of palmitic acid ester of 9-hydroxystearic acid.
Kuda, O., Brezinova, M., Silhavy, J., Landa, V., Zidek, V., Dodia, C., Kreuchwig, F., Vrbacky, M., Balas, L., Durand, T., Hübner, N., Fisher, A.B., Kopecky, J. and Pravenec, M.
Diabetes 67 (6): 1190-1199. June 2018

Solvent networks tune thermodynamics of oligosaccharide complex formation in an extended protein binding site.
Kunstmann, S., Gohlke, U., Broeker, N.K., Roske, Y., Heinemann, U., Santer, M. and Barbirz, S.
Journal of the American Chemical Society 140 (33): 10447-10455. 22 August 2018

Metagenomic analysis of gut microbial communities from a Central Asian population.
Kushugulova, A., Forslund, S.K., Costea, P.I., Kozhakhmetov, S., Khassenbekova, Z., Urazova, M., Nurgozhin, T., Zhumadilov, Z., Benberin, V., Driessen, M., Hercog, R., Voigt, A.Y., Benes, V., Kandels-Lewis, S., Sunagawa, S., Letunic, I. and Bork, P.
BMJ Open 8 (7): e021682. 28 July 2018

Antihypertensive treatment patterns and blood pressure control in older adults: results from the Berlin Aging Study II.
König, M., Gollasch, M., Rosada, A., Demuth, I., Spira, D. and Steinhagen-Thiessen, E.
Drugs & Aging 35 (11): 993-1003. November 2018

Mild-to-moderate chronic kidney disease and geriatric outcomes: analysis of cross-sectional data from the Berlin Aging Study II.
König, M., Gollasch, M., Spira, D., Buchmann, N., Hopfenmüller, W., Steinhagen-Thiessen, E. and Demuth, I.
Gerontology 64 (2): 118-126. February 2018

L

MYC-containing amplicons in acute myeloid leukemia: genomic structures, evolution, and transcriptional consequences.
L'Abbate, A., Tolomeo, D., Cifola, I., Severgnini, M., Turchiano, A., Augello, B., Squeo, G., D'Addabbo, P., Traversa, D., Daniele, G., Lonoce, A., Pafundi, M., Carella, M., Palumbo, O., Dolnik, A., Muehlematter, D., Schoumans, J., Van Roy, N., De Bellis, G., Martinelli, G., Merla, G., Bullinger, L., Haferlach, C. and Storlazzi, C.T.
Leukemia 32 (10): 2152-2166. October 2018

DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.
La Fortezza, M., Grigolon, G., Cosolo, A., Pindyurin, A., Breimann, L., Blum, H., van Steensel, B. and Classen, A.K.
Epigenetics & Chromatin 11 (1): 27. 5 June 2018

HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.
LaBranche, C.C., McGuire, A.T., Gray, M.D., Behrens, S., Chen, X., Zhou, T., Sattentau, Q.J., Peacock, J., Eaton, A., Greene, K., Gao, H., Tang, H., Perez, L.G., Saunders, K.O., Kwong, P.D., Mascola, J.R., Haynes, B.F., Stamatatos, L. and Montefiori, D.C.
PLoS Pathogens 14 (11): e1007431. 5 November 2018

Redundant regulation.
Lacadie, S.A. and Ohler, U.
Nature Ecology & Evolution 2 (3): 418-419. March 2018

Diabetes, but not hypertension and obesity, is associated with postoperative cognitive dysfunction.
Lachmann, G., Feinkohl, I., Borchers, F., Ottens, T.H., Nathoe, H.M., Sauer, A.M., Dieleman, J.M., Radtke, F.M., van Dijk, D., Spies, C. and Pischon, T.
Dementia and Geriatric Cognitive Disorders 46 (3-4): 193-206. 16 October 2018

Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs).
Lagies, S., Pichler, R., Kaminski, M.M., Schlimpert, M., Walz, G., Lienkamp, S.S. and Kammerer, B.
Scientific Reports 8 (1): 3878. 1 March 2018

Basal forebrain cholinergic system volume is associated with general cognitive ability in the elderly.
Lammers, F., Borchers, F., Feinkohl, I., Hendrikse, J., Kant, I.M.J., Kozma, P., Pischon, T., Slooter, A.J.C., Spies, C., van Montfort, S.J.T., Zacharias, N., Zaborszky, L. and Winterer, G.
Neuropsychologia 119 : 145-156. October 2018

Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates.
Langer, H.T., Senden, J.M.G., Gijsen, A.P., Kempa, S., van Loon, Luc J. C. and Spuler, S.
Frontiers in Physiology 9 : 1220. 31 August 2018

The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice.
Langhorst, H., Jüttner, R., Groneberg, D., Mohtashamdolatshahi, A., Pelz, L., Purfürst, B., Schmidt-Ott, K.M., Friebe, A. and Rathjen, F.G.
Disease Models & Mechanisms 11 (2): dmm032128. 22 February 2018

The biotrophic development of Ustilago maydis studied by RNA-seq analysis.
Lanver, D., Müller, A.N., Happel, P., Schweizer, G., Haas, F.B., Franitza, M., Pellegrin, C., Reissmann, S., Altmüller, J., Rensing, S.A. and Kahmann, R.
Plant Cell 30 (2): 300-323. February 2018

Size matters: grey matter brain reserve predicts executive functioning in the elderly.
Laubach, M., Lammers, F., Zacharias, N., Feinkohl, I., Pischon, T., Borchers, F, Slooter, A.J.C., Kühn, S., Spies, C. and Winterer, G.
Neuropsychologia 119 : 172-181. October 2018

Characterization of transcription termination-associated RNAs: new insights into their biogenesis, tailing, and expression in primary tumors.
Laudadio, I., Formichetti, S., Gioiosa, S., Klironomos, F., Rajewsky, N., Macino, G., Carissimi, C. and Fulci, V.
International Journal of Genomics 2018 : 1243858. 26 April 2018

The growth and evolution of cardiovascular magnetic resonance: a 20-year history of the Society for Cardiovascular Magnetic Resonance (SCMR) annual scientific sessions.
Lee, D.C., Markl, M., Dall'Armellina, E., Han, Y., Kozerke, S., Kuehne, T., Nielles-Vallespin, S., Messroghli, D., Patel, A., Schaeffter, T., Simonetti, O., Valente, A.M., Weinsaft, J.W., Wright, G., Zimmerman, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 20 (1): 8. 31 January 2018

mVOC 2.0: a database of microbial volatiles.
Lemfack, M.C., Gohlke, B.O., Toguem, S.M.T., Preissner, S., Piechulla, B. and Preissner, R.
Nucleic Acids Research 46 (D1): D1261-D1265. 4 January 2018

Warum die Deutsche Gesellschaft für Neurologie einen industrieunabhängigen Kongress braucht [Why German neurology needs an annual meeting without industry sponsorship].
Lempert, T., Janzen, R., Diehl, R., Stark, E., Paul, F., Wilke, C., Tavakolian, R., Völzke, E., von Brevern, M. and Möller, P.
Aktuelle Neurologie 45 (6): 429-433. August 2018

Integrating HDAd5/35++ vectors as a new platform for HSC gene therapy of hemoglobinopathies.
Li, C., Psatha, N., Wang, H., Singh, M., Samal, H.B., Zhang, W., Ehrhardt, A., Izsvák, Z., Papayannopoulou, T. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 9 : 142-152. 15 June 2018

Conditional deletion of FOXL2 and SMAD4 in gonadotropes of adult mice causes isolated FSH deficiency.
Li, Y., Schang, G., Wang, Y., Zhou, X., Levasseur, A., Boyer, A., Deng, C.X., Treier, M., Boehm, U., Boerboom, D. and Bernard, D.J.
Endocrinology 159 (7): 2641-2655. 1 July 2018

RXFP1 receptor activation by relaxin-2 induces vascular relaxation in mice via a Gα(i2)-protein/PI3Kß/γ/nitric oxide-coupled pathway.
Lian, X., Beer-Hammer, S., König, G.M., Kostenis, E., Nürnberg, B. and Gollasch, M.
Frontiers in Physiology 9 : 1234. September 2018

Top-NOTCH regulation of cardiac metabolism.
Lim, R. and Potente, M.
Circulation 137 (24): 2609-2612. 12 June 2018

Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill.
Lin, X., Noel, J.K., Wang, Q., Ma, J. and Onuchic, J.N.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): E7905-E7913. 21 August 2018

Engineering of human-induced pluripotent stem cells for precise disease modeling.
Lisowski, P.
In: Stem Cell Genetics for Biomedical Research: Past, Present, and Future. Springer, Cham, Switzerland, 369-411. ISBN 978-3-319-90694-2 2018

Mitochondria and the dynamic control of stem cell homeostasis.
Lisowski, P., Kannan, P., Mlody, B. and Prigione, A.
EMBO Reports 19 (5): e45432. 1 May 2018

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling.
Liss, M., Radke, M.H., Eckhard, J., Neuenschwander, M., Dauksaite, V., von Kries, J.P. and Gotthardt, M.
PLoS ONE 13 (6): e0198492. 11 June 2018

Structural basis for membrane tethering by a bacterial dynamin-like pair.
Liu, J., Noel, J.K. and Low, H.H.
Nature Communications 9 (1): 3345. 21 August 2018

A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging.
Liu, Y., Zhang, L., Nazare, M., Yao, Q. and Hu, H.Y.
Acta Pharmaceutica Sinica B 8 (3): 401-408. May 2018

Transient N-6-methyladenosine transcriptome sequencing reveals a regulatory role of m6A in splicing efficiency.
Louloupi, A., Ntini, E., Conrad, T. and Ørom, U.A.V.
Cell Reports 23 (12): 3429-3437. 19 June 2018

Salt, blood pressure, and aldosterone in women and men.
Luft, F.C.
Hypertension 71 (6): 1026-1027. June 2018

Pushing preeclampsia back to pre-preeclampsia.
Luft, F.C. and Dechend, R.
Trends in Cardiovascular Medicine 28 (8): 514-515. November 2018

Pendred, pendrin, pseudohypoaldosteronism type II, and renal tubular acidosis.
Luft, F.C. and Wagner, C.A.
Kidney International 94 (3): 457-459. September 2018

Circular RNAs in cancer.
Lux, S. and Bullinger, L.
Advances in Experimental Medicine and Biology 1087 : 215-230. 28 September 2018

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion.
Löber, U., Hobbs, M., Dayaram, A., Tsangaras, K., Jones, K., Alquezar-Planas, D.E., Ishida, Y., Meers, J., Mayer, J., Quedenau, C., Chen, W., Johnson, R.N., Timms, P., Young, P.R., Roca, A.L. and Greenwood, A.D.
Proceedings of the National Academy of Sciences of the United States of America 115 (34): 8609-8614. 21 August 2018

Alternatives to animal testing in basic and preclinical research of atopic dermatitis.
Löwa, A., Jevtić, M., Gorreja, F. and Hedtrich, S.
Experimental Dermatology 27 (5): 476-483. May 2018

Generation of full-thickness skin equivalents using hair follicle-derived primary human keratinocytes and fibroblasts.
Löwa, A., Vogt, A., Kaessmeyer, S. and Hedtrich, S.
Journal of Tissue Engineering and Regenerative Medicine 12 (4): e2134-e2146. April 2018

LRRC8/VRAC anion channels are required for late stages of spermatid development in mice.
Lück, J.C., Puchkov, D., Ullrich, F. and Jentsch, T.J.
Journal of Biological Chemistry 293 (30): 11796-11808. 27 July 2018

Pathway analysis hints towards beneficial effects of long-term vibration on human chondrocytes.
Lützenberg, R., Solano, K., Buken, C., Sahana, J., Riwaldt, S., Kopp, S., Krüger, M., Schulz, H., Saar, K., Huebner, N., Hemmersbach, R., Bauer, J., Infanger, M., Grimm, D. and Wehland, M.
Cellular Physiology and Biochemistry 47 (4): 1729-1741. 28 June 2018

M

Shearlet-based compressed sensing for fast 3D cardiac MR imaging using iterative reweighting.
Ma, J., März, M., Funk, S., Schulz-Menger, J., Kutyniok, G., Schaeffter, T. and Kolbitsch, C.
Physics in Medicine and Biology 63 (23): 235004. 22 November 2018

Reorganization of inter-chromosomal interactions in the 2q37-deletion syndrome.
Maass, P.G., Weise, A., Rittscher, K., Lichtenwald, J., Barutcu, A.R., Liehr, T., Aydin, A., Wefeld-Neuenfeld, Y., Pölsler, L., Tinschert, S., Rinn, J.L., Luft, F.C. and Bähring, S.
EMBO Journal 37 (15): e96257. 1 August 2018

Soluble B7-H4 blood serum levels are elevated in women at high risk for preeclampsia in the first trimester, as well as in patients with confirmed preeclampsia.
Mach, P., Nolte-Boenigk, L., Droste, L., Fox, L., Frank, M., Schmidt, B., Herse, F., Verlohren, S., Wicherek, L., Iannaccone, A., Birdir, C., Andrikos, D., Kimmig, R., Gellhaus, A. and Köninger, A.
American Journal of Reproductive Immunology 80 (3): e12988. September 2018

Extensive impact of non-antibiotic drugs on human gut bacteria.
Maier, L., Pruteanu, M., Kuhn, M., Zeller, G., Telzerow, A., Anderson, E.E., Brochado, A.R., Fernandez, K.C., Dose, H., Mori, H., Patil, K.R., Bork, P. and Typas, A.
Nature 555 (7698): 623-628. 29 March 2018

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.
Maifrede, S., Nieborowska-Skorska, M., Sullivan-Reed, K., Dasgupta, Y., Podszywalow-Bartnicka, P., Le, B.V., Solecka, M., Lian, Z., Belyaeva, E.A., Nersesyan, A., Machnicki, M.M., Toma, M., Chatain, N., Rydzanicz, M., Zhao, H., Jelinek, J., Piwocka, K., Sliwinski, T., Stoklosa, T., Ploski, R., Fischer, T., Sykes, S.M., Koschmieder, S., Bullinger, L., Valent, P., Wasik, M.A., Huang, J. and Skorski, T.
Blood 132 (1): 67-77. 5 July 2018

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.
Makarewich, C.A., Munir, A.Z., Schiattarella, G.G., Bezprozvannaya, S., Raguimova, O.N., Cho, E.E., Vidal, A.H., Robia, S.L., Bassel-Duby, R. and Olson, E.N.
eLife 7 : e38319. 9 October 2018

Exon skipping in a Dysf-missense mutant mouse model.
Malcher, J., Heidt, L., Goyenvalle, A., Escobar, H., Marg, A., Beley, C., Benchaouir, R., Bader, M., Spuler, S., García, L. and Schöwel, V.
Molecular Therapy - Nucleic Acids 13 : 198-207. 7 December 2018

Transient receptor potential vanilloid 4 channel deficiency aggravates tubular damage after acute renal ischaemia reperfusion.
Mannaa, M., Markó, L., Balogh, A., Vigolo, E., N'diaye, G., Kaßmann, M., Michalick, L., Weichelt, U., Schmidt-Ott, K.M., Liedtke, W.B., Huang, Y., Müller, D.N., Kuebler, W.M. and Gollasch, M.
Scientific Reports 8 (1): 4878. 20 March 2018

Evaluation of food allergy candidate loci in the Genetics of Food Allergy Study.
Marenholz, I., Grosche, S., Rüschendorf, F., Kalb, B., Blumchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Yürek, S., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hubner, N., Niggemann, B., Beyer, K. and Lee, Y.A.
Journal of Allergy and Clinical Immunology 142 (4): 1368-1370. October 2018

Challenges and guidelines toward 4D nucleome data and model standards.
Marti-Renom, M.A., Almouzni, G., Bickmore, W.A., Bystricky, K., Cavalli, G., Fraser, P., Gasser, S.M., Giorgetti, L., Heard, E., Nicodemi, M., Nollmann, M., Orozco, M., Pombo, A. and Torres-Padilla, M.E.
Nature Genetics 50 (10): 1352-1358. October 2018

Mutations in TOP3A cause a bloom syndrome-like disorder.
Martin, C.A., Sarlós, K., Logan, C.V., Thakur, R.S., Parry, D.A., Bizard, A.H., Leitch, A., Cleal, L., Ali, N.S., Al-Owain, M.A., Allen, W., Altmüller, J., Aza-Carmona, M., Barakat, B.A.Y., Barraza-García, J., Begtrup, A., Bogliolo, M., Cho, M.T., Cruz-Rojo, J., Dhahrabi, H.A.M., Elcioglu, N.H., Gorman, G.S., Jobling, R., Kesterton, I., Kishita, Y., Kohda, M., Le Quesne Stabej, P., Malallah, A.J., Nürnberg, P., Ohtake, A., Okazaki, Y., Pujol, R., Ramirez, M.J., Revah-Politi, A., Shimura, M., Stevens, P., Taylor, R.W., Turner, L., Williams, H., Wilson, C., Yigit, G., Zahavich, L., Alkuraya, F.S., Surralles, J., Iglesias, A., Murayama, K., Wollnik, B., Dattani, M., Heath, K.E., Hickson, I.D. and Jackson, A.P.
American Journal of Human Genetics 103 (2): 221-231. 2 August 2018

Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo.
Maschmeyer, P., Petkau, G., Siracusa, F., Zimmermann, J., Zügel, F., Kühl, A.A., Lehmann, K., Schimmelpfennig, S., Weber, M., Haftmann, C., Riedel, R., Bardua, M., Heinz, G.A., Tran, C.L., Hoyer, B.F., Hiepe, F., Herzog, S., Wittmann, J., Rajewsky, N., Melchers, F.G., Chang, H.D., Radbruch, A. and Mashreghi, M.F.
Journal of Autoimmunity 89 : 41-52. May 2018

Toward living nanomachines.
Mast, C., Möller, F., Kreysing, M., Schink, S., Obermayer, B., Gerland, U. and Braun, D.
In: Living machines: a handbook of research in biomimetics and biohybrid systems. Oxford University Press, Oxford, 380-389. ISBN 9780199674923 2018

How to make a tumour: cell type specific dissection of Ustilago maydis-induced tumour development in maize leaves.
Matei, A., Ernst, C., Günl, M., Thiele, B., Altmüller, J., Walbot, V., Usadel, B. and Doehlemann, G.
New Phytologist 217 (4): 1681-1695. March 2018

Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis.
Matthes, F., Hettich, M.M., Schilling, J., Flores-Dominguez, D., Blank, N., Wiglenda, T., Buntru, A., Wolf, H., Weber, S., Vorberg, I., Dagane, A., Dittmar, G., Wanker, E., Ehninger, D. and Krauss, S.
Cell Death Discovery 4 : 4. 29 January 2018

Reducing mutant huntingtin protein expression in living cells by a newly identified RNA CAG binder.
Matthes, F., Massari, S., Bochicchio, A., Schorpp, K., Schilling, J., Weber, S., Offermann, N., Desantis, J., Wanker, E.E., Carloni, P., Hadian, K., Tabarrini, O., Rossetti, G. and Krauss, S.
ACS Chemical Neuroscience 9 (6): 1399-1408. 20 June 2018

Peripheral serotonin synthesis as a new drug target.
Matthes, S. and Bader, M.
Trends in Pharmacological Sciences 39 (6): 560-572. June 2018

Rare coding variants in genes encoding GABA A receptors in genetic generalised epilepsies: an exome-based case-control study.
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Lancet Neurology 17 (8): 699-708. August 2018

Vaccines and the association with relapses in patients with neuromyelitis optica spectrum disorder.
Mealy, M.A., Cook, L.J., Pache, F., Velez, D.L., Borisow, N., Becker, D., Jimenez Arango, J.A., Paul, F. and Levy, M.
Multiple Sclerosis and Related Disorders 23 : 78-82. July 2018

Aquaporin-4 serostatus does not predict response to immunotherapy in neuromyelitis optica spectrum disorders.
Mealy, M.A., Kim, S.H., Schmidt, F., López, R., Jimenez Arango, J.A., Paul, F., Wingerchuk, D.M., Greenberg, B.M., Kim, H.Jin. and Levy, M.
Multiple Sclerosis Journal 24 (13): 1737-1742. 1 November 2018

Brain region-specific expression of genes mapped within quantitative trait loci for behavioral responsiveness to acute stress in Fisher 344 and Wistar Kyoto male rats.
Meckes, J.K., Lim, P.H., Wert, S.L., Luo, W., Gacek, S.A., Platt, D., Jankord, R., Saar, K. and Redei, E.E.
PLoS ONE 13 (3): e0194293. 12 March 2018

Mutant screen reveals the Piccolo's control over depression and brain-gonad crosstalk.
Medrano, G.A., Singh, M., Plautz, E.J., Good, L.B., Chapman, K.M., Chaudhary, J., Jaichander, P., Powell, H.M., Pudasaini, A., Shelton, J.M., Richardson, J.A., Xie, X.J., Ivics, Z., Braun, C., Ackermann, F., Garner, C.C., Izsvak, Z. and Hamra, F.K.
bioRxiv : 405985. 31 August 2018

User experience and clinical effectiveness with two wearable global positioning system devices in home dementia care.
Megges, H., Freiesleben, S.D., Rösch, C., Knoll, N., Wessel, L. and Peters, O.
Alzheimer's and Dementia: Translational Research and Clinical Interventions 4 : 636-644. 9 November 2018

Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations.
Meral, D., Provasi, D., Prada-Gracia, D., Möller, J., Marino, K., Lohse, M.J. and Filizola, M.
Scientific Reports 8 (1): 7705. 16 May 2018

Generation of human induced pluripotent stem cells (EURACi001-A, EURACi002-A, EURACi003-A) from peripheral blood mononuclear cells of three patients carrying mutations in the CAV3 gene.
Meraviglia, V., Benzoni, P., Landi, S., Murano, C., Langione, M., Motta, B.M., Baratto, S., Silipigni, R., Di Segni, M., Pramstaller, P.P., DiFrancesco, D., Gazzerro, E., Barbuti, A. and Rossini, A.
Stem Cell Research 27 : 25-29. March 2018

Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity.
Merks, A.M., Swinarski, M., Meyer, A.M., Müller, N.V., Özcan, I., Donat, S., Burger, A., Gilbert, S., Mosimann, C., Abdelilah-Seyfried, S. and Panáková, D.
Nature Communications 9 (1): 2161. 4 June 2018

Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry.
Mertins, P., Tang, L.C., Krug, K., Clark, D.J., Gritsenko, M.A., Chen, L., Clauser, K.R., Clauss, T.R., Shah, P., Gillette, M.A., Petyuk, V.A., Thomas, S.N., Mani, D.R., Mundt, F., Moore, R.J., Hu, Y., Zhao, R., Schnaubelt, M., Keshishian, H., Monroe, M.E., Zhang, Z., Udeshi, N.D., Mani, D., Davies, S.R., Townsend, R.R., Chan, D.W., Smith, R.D., Zhang, H., Liu, T. and Carr, S.A.
Nature Protocols 13 (7): 1632-1661. July 2018

Synthetic embryology: controlling geometry to model early mammalian development.
Metzger, J.J., Simunovic, M. and Brivanlou, A.H.
Current Opinion in Genetics & Development 52 : 86-91. October 2018

Nervous system regionalization entails axial allocation before neural differentiation.
Metzis, V., Steinhauser, S., Pakanavicius, E., Gouti, M., Stamataki, D., Ivanovitch, K., Watson, T., Rayon, T., Mousavy Gharavy, S.N., Lovell-Badge, R., Luscombe, N.M. and Briscoe, J.
Cell 175 (4): 1105-1118. 1 November 2018

Silencing the CSF-1 axis using nanoparticle encapsulated siRNA mitigates viral and autoimmune myocarditis.
Meyer, I.S., Goetzke, C.C., Kespohl, M., Sauter, M., Heuser, A., Eckstein, V., Vornlocher, H.P., Anderson, D.G., Haas, J., Meder, B., Katus, H.A., Klingel, K., Beling, A. and Leuschner, F.
Frontiers in Immunology 9 : 2303. 8 October 2018

Mutations in disordered regions can cause disease by creating dileucine motifs.
Meyer, K., Kirchner, M., Uyar, B., Cheng, J.Y., Russo, G., Hernandez-Miranda, L.R., Szymborska, A., Zauber, H., Rudolph, I.M., Willnow, T.E., Akalin, A., Haucke, V., Gerhardt, H., Birchmeier, C., Kühn, R., Krauss, M., Diecke, S., Pascual, J.M. and Selbach, M.
Cell 175 (1): 239-253. 20 September 2018

Oligodendrocytes in the mouse corpus callosum maintain axonal function by delivery of glucose.
Meyer, N., Richter, N., Fan, Z., Siemonsmeier, G., Pivneva, T., Jordan, P., Steinhäuser, C., Semtner, M., Nolte, C. and Kettenmann, H.
Cell Reports 22 (9): 2383-2394. 27 February 2018

The angiotensin II type 2 receptors protect renal tubule mitochondria in early stages of diabetes mellitus.
Micakovic, T., Papagiannarou, S., Clark, E., Kuzay, Y., Abramovic, K., Peters, J., Sticht, C., Volk, N., Fleming, T., Nawroth, P., Hammes, H.P., Alenina, N., Gröne, H.J. and Hoffmann, S.C.
Kidney International 94 (5): 937-950. November 2018

Convergence to equilibrium in energy-reaction–diffusion systems using vector-valued functional inequalities.
Mielke, A. and Mittnenzweig, M.
Journal of Nonlinear Science 28 (2): 765-806. April 2018

The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N., Kolesnichenko, M., Beaudette, P., Popp, O., Uyar, B., Sun, W., Tufan, A.B., Perder, B., Akalin, A., Chen, W., Mertins, P., Dittmar, G., Hinz, M. and Scheidereit, C.
EMBO Journal 37 (24): e98658. 14 December 2018

Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M., Fan, D.N.Y., Belenki, D., Däbritz, J.H.M., Zhao, Z., Yu, Y., Dörr, J.R., Dimitrova, L., Lenze, D., Monteiro Barbosa, I.A., Mendoza-Parra, M.A., Kanashova, T., Metzner, M., Pardon, K., Reimann, M., Trumpp, A., Dörken, B., Zuber, J., Gronemeyer, H., Hummel, M., Dittmar, G., Lee, S. and Schmitt, C.A.
Nature 553 (7686): 96-100. 4 January 2018