Article
KCNQ1, KCNE2, and Na(+)-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability.
Abbott, G.W, Tai, K.K., Neverisky, D.L., Hansler, A., Hu, Z., Roepke, T.K., Lerner, D.J., Chen, Q., Liu, L., Zupan, B., Toth, M., Haynes, R., Huang, X., Demirbas, D., Buccafusca, R., Gross, S.S., Kanda, V.A. and Berry, G.T.
Science Signaling 7
(315): ra22.
4 March 2014
The crystal structure of the RhoA-AKAP-Lbc DH-PH domain complex.
Abdul Azeez, K.R., Knapp, S., Fernandes, J.M.P., Klussmann, E. and Elkins, J.M.
Biochemical Journal 464
(2): 231-239.
1 December 2014
Restoration of muscle strength in dystrophic muscle by Angiotensin-1-7 through inhibition of TGF-β signaling.
Acuna, M.J., Pessina, P., Olguin, H., Cabrera, D., Vio, C.P., Bader, M., Munoz-Canoves, P., Santos, R.A., Cabello-Verrugio, C. and Brandan, E.
Human Molecular Genetics 23
(5): 1237-1249.
1 March 2014
SecA defects are accompanied by dysregulation of MukB, DNA gyrase, chromosome partitioning and DNA superhelicity in Escherichia coli.
Adachi, S., Murakawa, Y. and Hiraga, S.
Microbiology 160
(Pt 8): 1648-1658.
August 2014
Role of CYP1A1 in modulating the vascular and blood pressure benefits of omega-3 polyunsaturated fatty acids.
Agbor, L.N., Wiest, E.F., Rothe, M., Schunck, W.H. and Walker, M.K.
Journal of Pharmacology and Experimental Therapeutics 351
(3): 688-698.
December 2014
Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
Aksoy, I., Giudice, V., Delahaye, E., Wianny, F., Aubry, M., Mure, M., Chen, J., Jauch, R., Bogu, G.K., Nolden, T., Himmelbauer, H., Doss, M.X., Sachinidis, A., Schulz, H., Hummel, O., Martinelli, P., Hübner, N., Stanton, L.W., Real, F.X., Bourillot, P.Y. and Savatier, P.
Nature Communications 5
: 3719.
28 April 2014
Rare variants in NR2F2 cause congenital heart defects in humans.
Al Turki, S., Manickaraj, A.K., Mercer, C.L., Gerety, S.S., Hitz, M.P., Lindsay, S., D'Alessandro, L.C.A., Swaminathan, G.J., Bentham, J., Arndt, A.K., Low, J., Breckpot, J., Gewillig, M., Thienpont, B., Abdul-Khaliq, H., Harnack, C., Hoff, K., Kramer, H.H., Schubert, S., Siebert, R., Toka, O., Cosgrove, C., Watkins, H., Lucassen, A.M., O'Kelly, I.M., Salmon, A.P., Bu'Lock, F.A., Granados-Riveron, J., Setchfield, K., Thornborough, C., Brook, J.D., Mulder, B., Klaassen, S., Bhattacharya, S., Devriendt, K., Fitzpatrick, D.F., Wilson, D.I., Mital, S. and Hurles, M.E.
American Journal of Human Genetics 94
(4): 574-585.
3 April 2014
Inflammatory and metabolic biomarkers and risk of liver and biliary tract cancer.
Aleksandrova, K., Boeing, H., Nöthlings, U., Jenab, M., Fedirko, V., Kaaks, R., Lukanova, A., Trichopoulou, A., Trichopoulos, D., Boffetta, P., Trepo, E., Westhpal, S., Duarte-Salles, T., Stepien, M., Overvad, K., Tjønneland, A., Halkjaer, J., Boutron-Ruault, M.C., Dossus, L., Racine, A., Lagiou, P., Bamia, C., Benetou, V., Agnoli, C., Palli, D., Panico, S., Tumino, R., Vineis, P., Bueno-de-Mesquita, B., Peeters, P.H., Gram, I.T., Lund, E., Weiderpass, E., Quirós, J.R., Agudo, A., Sánchez, M.J., Gavrila, D., Barricarte, A., Dorronsoro, M., Ohlsson, B., Lindkvist, B., Johansson, A., Sund, M., Khaw, K.T., Wareham, N., Travis, R.C., Riboli, E. and Pischon, T.
Hepatology 60
(3): 858-871.
September 2014
Adiposity, mediating biomarkers and risk of colon cancer in the European prospective investigation into cancer and nutrition study.
Aleksandrova, K., Drogan, D., Boeing, H., Jenab, M., Bueno-de-Mesquita, H.B., Jansen, E., van Duijnhoven, F.J.B., Rinaldi, S., Fedirko, V., Romieu, I., Kaaks, R., Riboli, E., Gunter, M.J., Romaguera, D., Westhpal, S., Overvad, K., Tjønneland, A., Halkjaer, J., Boutron-Ruault, M.C., Clavel-Chapelon, F., Lukanova, A., Trichopoulou, A., Trichopoulos, D., Vidalis, P., Panico, S., Agnoli, C., Palli, D., Tumino, R., Vineis, P., Buckland, G., Sánchez-Cruz, J.J., Dorronsoro, M., Tormo Díaz, M.J., Barricarte, A., Quiros, J.R., Peeters, P.H., May, A., Hallmans, G., Palmqvist, R., Crowe, F.L., Khaw, K.T., Wareham, N. and Pischon, T.
International Journal of Cancer 134
(3): 612-621.
1 February 2014
Biomarker patterns of inflammatory and metabolic pathways are associated with risk of colorectal cancer: results from the European Prospective Investigation into Cancer and Nutrition (EPIC).
Aleksandrova, K., Jenab, M., Bueno-de-Mesquita, H.B., Fedirko, V., Kaaks, R., Lukanova, A., van Duijnhoven, F.J.B., Jansen, E., Rinaldi, S., Romieu, I., Ferrari, P., Murphy, N., Gunter, M.J., Riboli, E., Westhpal, S., Overvad, K., Tjønneland, A., Halkjær, J., Boutron-Ruault, M.C., Dossus, L., Racine, A., Trichopoulou, A., Bamia, C., Orfanos, P., Agnoli, C., Palli, D., Panico, S., Tumino, R., Vineis, P., Peeters, P.H., Duell, E.J., Molina-Montes, E., Quirós, J.R., Dorronsoro, M., Chirlaque, M.D., Barricarte, A., Ljuslinder, I., Palmqvist, R., Travis, R.C., Khaw, K.T., Wareham, N., Pischon, T. and Boeing, H.
European Journal of Epidemiology 29
(4): 261-275.
1 April 2014
Combined impact of healthy lifestyle factors on colorectal cancer: a large European cohort study.
Aleksandrova, K., Pischon, T., Jenab, M., Bueno-de-Mesquita, H., Fedirko, V., Norat, T., Romaguera, D., Knüppel, S., Boutron-Ruault, M.C., Dossus, L., Dartois, L., Kaaks, R., Li, K., Tjønneland, A., Overvad, K., Quirós, J., Buckland, G., Sánchez, M., Dorronsoro, M., Chirlaque, M.D., Barricarte, A., Khaw, K.T., Wareham, N.J., Bradbury, K.E., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Palli, D., Krogh, V., Tumino, R., Naccarati, A., Panico, S., Siersema, P.D., Peeters, P., Ljuslinder, I., Johansson, I., Ericson, U., Ohlsson, B., Weiderpass, E., Skeie, G., Borch, K., Rinaldi, S., Romieu, I., Kong, J., Gunter, M.J., Ward, H.A., Riboli, E. and Boeing, H.
BMC Medicine 12
(1): 168.
10 October 2014
Improving topical non-melanoma skin cancer treatment: In vitro efficacy of a novel guanosine-analog phosphonate.
Ali-von Laue, C., Zoschke, C., Do, N., Lehnen, D., Küchler, S., Mehnert, W., Blaschke, T., Kramer, K.D., Plendl, J., Weindl, G., Korting, H.C., Hoeller Obrigkeit, D., Merk, H.F. and Schäfer-Korting, M.
Skin Pharmacology and Physiology 27
(4): 173.
May 2014
Relationship between genome and epigenome - challenges and requirements for future research.
Almouzni, G., Altucci, L., Amati, B., Ashley, N., Baulcombe, D., Beaujean, N., Bock, C., Bongcam-Rudloff, E., Bousquet, J., Braun, S., Bressac-de Paillerets, B., Bussemakers, M., Clarke, L., Conesa, A., Estivill, X., Fazeli, A., Grgurević, N., Gut, I., Heijmans, B.T., Hermouet, S., Houwing-Duistermaat, J., Iacobucci, I., Ilaš, J., Kandimalla, R., Krauss-Etschmann, S., Lasko, P., Lehmann, S., Lindroth, A., Majdič, G., Marcotte, E., Martinelli, G., Martinet, N., Meyer, E., Miceli, C., Mills, K., Moreno-Villanueva, M., Morvan, G., Nickel, D., Niesler, B., Nowacki, M., Nowak, J., Ossowski, S., Pelizzola, M., Pochet, R., Potočnik, U., Radwanska, M., Raes, J., Rattray, M., Robinson, M.D., Roelen, B., Sauer, S., Schinzer, D., Slagboom, E., Spector, T., Stunnenberg, H.G., Tiligada, E., Torres-Padilla, M.E., Tsonaka, R., Van Soom, A., Vidaković, M. and Widschwendter, M.
BMC Genomics 15
: 487.
18 June 2014
Penetration of normal, damaged and diseased skin--an in vitro study on dendritic core-multishell nanotransporters.
Alnasif, Nesrin, Zoschke, Christian, Fleige, Emanuel, Brodwolf, Robert, Boreham, Alexander, Rühl, Eckart, Eckl, K.M., Merk, Hans-Friedrich, Hennies, H.C., Alexiev, Ulrike, Haag, Rainer, Küchler, S. and Schäfer-Korting, Monika
Journal of Controlled Release 185
: 45-50.
10 July 2014
Multimodal retinal vessel analysis in CADASIL patients.
Alten, F., Motte, J., Ewering, C., Osada, N., Clemens, C.R., Kadas, E.M., Eter, N., Paul, F. and Marziniak, M.
PLoS ONE 9
(11): e112311.
5 November 2014
Enrichment of target sequences for next-generation sequencing applications in research and diagnostics.
Altmüller, J., Budde, B.S. and Nürnberg, P.
Biological Chemistry 395
(2): 231-237.
1 February 2014
Progesterone supplementation attenuates hypertension and the autoantibody to the angiotensin II type I receptor in response to elevated interleukin-6 during pregnancy.
Amaral, L.M., Kipprono, L., Cornelius, D.C., Shoemaker, C., Wallace, K., Moseley, J., Wallukat, G., Martin, J.N., Dechend, R. and Lamarca, B.
American Journal of Obstetrics and Gynecology 211
(2): 158.e1-158.e6.
August 2014
Reduced oxygen uptake efficiency slope in patients with cardiac sarcoidosis.
Ammenwerth, W., Wurps, H., Klemens, M.A., Crolow, C., Schulz-Menger, J., Schoenfeld, N., Bittner, R.C. and Bauer, T.T.
PLoS ONE 9
(7): e102333.
16 July 2014
Drep-2 is a novel synaptic protein important for learning and memory.
Andlauer, T.F.M., Scholz-Kornehl, S., Tian, R., Kirchner, M., Babikir, H.A., Depner, H., Loll, B., Quentin, C., Gupta, V.K., Holt, M.G., Dipt, S., Cressy, M., Wahl, M.C., Fiala, A., Selbach, M., Schwärzel, M. and Sigrist, S.J.
eLife 3
: e03895.
13 November 2014
Epigenetic switch at Atp2a2 and Myh7 gene promoters in pressure overload-induced heart failure.
Angrisano, T., Schiattarella, G.G., Keller, S., Pironti, G., Florio, E., Magliulo, F., Bottino, R., Pero, R., Lembo, F., Avvedimento, E.V., Esposito, G., Trimarco, B., Chiariotti, L. and Perrino, C.
PLoS ONE 9
(9): e106024.
2 September 2014
Quantitative profiling of Drosophila melanogaster Dscam1 isoforms reveals no changes in splicing after bacterial exposure.
Armitage, S.A.O., Sun, W., You, X., Kurtz, J., Schmucker, D. and Chen, W.
PLoS ONE 9
(10): e108660.
13 October 2014
circRNA biogenesis competes with pre-mRNA splicing.
Ashwal-Fluss, R., Meyer, M., Pamudurti, N.R., Ivanov, A., Bartok, O., Hanan, M., Evantal, N., Memczak, S., Rajewsky, N. and Kadener, S.
Molecular Cell 56
(1): 55-66.
2 October 2014
IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors.
Authier, H., Billot, K., Derudder, E., Bordereaux, D., Riviere, P., Rodrigues-Ferreira, S., Nahmias, C. and Baud, V.
Proceedings of the National Academy of Sciences of the United States of America 111
(41): 14794-14799.
14 October 2014
STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis.
Backert, I., Koralov, S.B., Wirtz, S., Kitowski, V., Billmeier, U., Martini, E., Hofmann, K., Hildner, K., Wittkopf, N., Brecht, K., Waldner, M., Rajewsky, K., Neurath, M.F., Becker, C. and Neufert, C.
Journal of Immunology 193
(7): 3779-3791.
1 October 2014
Gene expression profiling in PC12 cells infected with an oncolytic Newcastle disease virus strain.
Balogh, A., Bátor, J., Markó, L., Németh, M., Pap, M., Sétáló, G., Müller, D.N., Csatary, L.K. and Szeberényi, J.
Virus Research 185
: 10-22.
24 June 2014
Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types.
Balogh, A., Németh, M., Koloszár, I., Markó, L., Przybyl, L., Jinno, K., Szigeti, C., Heffer, M., Gebhardt, M., Szeberényi, J., Müller, D.N., Sétáló, G. and Pap, M.
Apoptosis 19
(7): 1080-1098.
1 July 2014
Avosentan is protective in hypertensive nephropathy at doses not causing fluid retention.
Baltatu, O.C., Zaugg, C.E., Schumacher, C., Louie, P., Campos, L.A. and Bader, M.
Pharmacological Research 80
: 9-13.
February 2014
Outlier-based identification of copy number variations using targeted resequencing in a small cohort of patients with tetralogy of fallot.
Bansal, V., Dorn, C., Grunert, M., Klaassen, S., Hetzer, R., Berger, F. and Sperling, S.R.
PLoS ONE 9
(1): e85375.
6 January 2014
Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats.
Barmashenko, G., Buttgereit, J., Herring, N., Bader, M., Oezcelik, C., Manahan-Vaughan, D. and Braunewell, K.H.
Frontiers in Molecular Neuroscience 7
: 95.
1 December 2014
CLCN7 and TCIRG1 mutations differentially affect bone matrix mineralization in osteopetrotic individuals.
Barvencik, F., Kurth, I., Koehne, T., Stauber, T., Zustin, J., Tsiakas, K., Ludwig, C.F., Beil, F.T., Pestka, J.M., Hahn, M., Santer, R., Supanchart, C., Kornak, U., Del Fattore, A., Jentsch, T., Teti, A., Schulz, A., Schinke, T. and Amling, M.
Journal of Bone and Mineral Research 29
(4): 982-991.
April 2014
Mutations in POGLUT1, encoding protein o-glucosyltransferase 1, cause autosomal-dominant Dowling-Degos disease.
Basmanav, F.B., Oprisoreanu, A.M., Pasternack, S.M., Thiele, H., Fritz, G., Wenzel, J., Größer, L., Wehner, M., Wolf, S., Fagerberg, C., Bygum, A., Altmüller, J., Rütten, A., Parmentier, L., El Shabrawi-Caelen, L., Hafner, C., Nürnberg, P., Kruse, R., Schoch, S., Hanneken, S. and Betz, R.C.
American Journal of Human Genetics 94
(1): 135-143.
2 January 2014
Genomes and phenomes of a population of outbred rats and its progenitors.
Baud, A., Guryev, V., Hummel, O., Johannesson, M. and Flint, J.
Scientific Data 1
: 140011.
10 June 2014
Macrophage infection via selective capture of HIV-1-infected CD4(+) T cells.
Baxter, A.E., Russell, R.A., Duncan, C.J.A., Moore, M.D., Willberg, C.B., Pablos, J.L., Finzi, A., Kaufmann, D.E., Ochsenbauer, C., Kappes, J.C., Groot, F. and Sattentau, Q.J.
Cell Host & Microbe 16
(6): 711-721.
10 December 2014
Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation.
Bazzini, A.A., Johnstone, T.G., Christiano, R., Mackowiak, S.D., Obermayer, B., Fleming, E.S., Vejnar, C.E., Lee, M.T., Rajewsky, N., Walther, T.C. and Giraldez, A.J.
EMBO Journal 33
(9): 981-993.
2 May 2014
Higher relative risk for multiple sclerosis in a pediatric and adolescent diabetes population: analysis from DPV data base.
Bechtold, S., Blaschek, A., Raile, K., Dost, A., Freiberg, C., Askenas, M., Froehlich-Reiterer, E., Molz, E. and Holl, R.W.
Diabetes Care 37
(1): 96-101.
January 2014
Mutation of POC1B in a severe syndromic retinal ciliopathy.
Beck, B.B., Phillips, J.B., Bartram, M.P., Wegner, J., Thoenes, M., Pannes, A., Sampson, J., Heller, R., Göbel, H., Koerber, F., Neugebauer, A., Hedergott, A., Nürnberg, G., Nürnberg, P., Thiele, H., Altmüller, J., Toliat, M.R., Staubach, S., Boycott, K.M., Valente, E.M., Janecke, A.R., Eisenberger, T., Bergmann, C., Tebbe, L., Wang, Y., Wu, Y., Fry, A.M., Westerfield, M., Wolfrum, U. and Bolz, H.J.
Human Mutation 35
(10): 1153-1162.
October 2014
Meglitinide analogues in adolescent patients with HNF1A-MODY (MODY 3).
Becker, M., Galler, A. and Raile, K.
Pediatrics 133
(3): e775-e779.
1 March 2014
PRC1-mediated gene silencing in pluripotent ES cells: function and evolution.
Becker, M., Mah, N., Zdzieblo, D., Li, X., Mer, A.S., Andrade-Navarro, M.A. and Mueller, A.M.
Epigenetics and Human Health 2015
: 141-166.
18 November 2014
Differential activation of natriuretic peptide receptors modulates cardiomyocyte proliferation during development.
Becker, J.R., Chatterjee, S., Robinson, T.Y., Bennett, J.S., Panáková, D., Galindo, C.L., Zhong, L., Shin, J.T., Coy, S.M., Kelly, A.E., Roden, D.M., Lim, C.C. and MacRae, C.A.
Development 141
(2): 335-345.
January 2014
Vascular receptor autoantibodies in pulmonary arterial hypertension associated with systemic sclerosis.
Becker, M.O., Kill, A., Kutsche, M., Guenther, J., Rose, A., Tabeling, C., Witzenrath, M., Kühl, A.A., Heidecke, H., Ghofrani, H.A., Tiede, H., Schermuly, R.T., Nickel, N., Hoeper, M.M., Lukitsch, I., Gollasch, M., Kuebler, W.M., Bock, S., Burmester, G.R., Dragun, D. and Riemekasten, G.
American Journal of Respiratory and Critical Care Medicine 190
(7): 808-817.
1 October 2014
The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression.
Becker, M.S., Schmezer, P., Breuer, R., Haas, S.F., Essers, M.A., Krammer, P.H. and Li-Weber, M.
Cell Death & Disease 5
: e1000.
January 2014
Using perceptive computing in multiple sclerosis - the Short Maximum Speed Walk test.
Behrens, J., Pfueller, C., Mansow-Model, S., Otte, K., Paul, F. and Brandt, A.U.
Journal of Neuroengineering and Rehabilitation 11
: 89.
27 May 2014
Structural identification of the VPS18 β-propeller reveals a critical role in the HOPS complex stability and function.
Behrmann, H., Lürick, A., Kuhlee, A., Kleine Balderhaar, H., Bröcker, C., Kümmel, D., Engelbrecht-Vandré, S., Gohlke, U., Raunser, S., Heinemann, U. and Ungermann, C.
Journal of Biological Chemistry 289
(48): 33503-33512.
28 November 2014
Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly.
Belz, K., Schoeneberger, H., Wehner, S., Weigert, A., Boenig, H., Klingebiel, T., Fichtner, I. and Fulda, S.
Blood 124
(2): 240-250.
10 July 2014
Simultaneous Raman microspectroscopy and fluorescence imaging of bone mineralization in living zebrafish larvae.
Bennet, M., Akiva, A., Faivre, D., Malkinson, G., Yaniv, K., Abdelilah-Seyfried, S., Fratzl, P. and Masic, A.
Biophysical Journal 106
(4): L17-L19.
18 February 2014
The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.
Bentley, K., Franco, C.A., Philippides, A., Blanco, R., Dierkes, M., Gebala, V., Stanchi, F., Jones, M., Aspalter, I.M., Cagna, G., Weström, S., Claesson-Welsh, L., Vestweber, D. and Gerhardt, H.
Nature Cell Biology 16
(4): 309-321.
April 2014
Computer simulations reveal complex distribution of haemodynamic forces in a mouse retina model of angiogenesis.
Bernabeu, M.O., Jones, M.L., Nielsen, J.H., Krüger, T., Nash, R.W., Groen, D., Schmieschek, S., Hetherington, J., Gerhardt, H., Franco, C.A. and Coveney, P.V.
Journal of the Royal Society Interface 11
(99): 20140543.
6 October 2014
199th ENMC international workshop: FHL1 related myopathies, June 7-9, 2013, Naarden, The Netherlands.
Bertrand, A.T., Boennemann, C.G. and Bonne, G.
Neuromuscular Disorders 24
(5): 453-462.
May 2014
Reference intervals for insulin-like growth factor-1 (IGF-1) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-1 immunoassay conforming to recent international recommendations.
Bidlingmaier, M., Friedrich, N., Emeny, R.T., Spranger, J., Wolthers, O.D., Roswall, J., Koerner, A., Obermayer-Pietsch, B., Huebener, C., Dahlgren, J., Frystyk, J., Pfeiffer, A.F.H., Doering, A., Bielohuby, M., Wallaschofski, H. and Arafat, A.M.
Journal of Clinical Endocrinology and Metabolism 99
(5): 1712-1721.
May 2014
Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer.
Birol, M., Enchev, R.I., Padilla, A., Stengel, F., Aebersold, R., Betzi, S., Yang, Y., Hoh, F., Peter, M., Dumas, C. and Echalier, A.
PLoS ONE 9
(8): e105688.
21 August 2014
CAFE: an R package for the detection of gross chromosomal abnormalities from gene expression microarray data.
Bollen, S., Leddin, M., Andrade-Navarro, M.A. and Mah, N.
Bioinformatics 30
(10): 1484-1485.
15 May 2014
Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.
Borcherds, W., Theillet, F.X., Katzer, A., Finzel, A., Mishall, K.M., Powell, A.T., Wu, H., Manieri, W., Dieterich, C., Selenko, P., Loewer, A. and Daughdrill, G.W.
Nature Chemical Biology 10
(12): 1000-1002.
December 2014
Pregnancy in multiple sclerosis: a questionnaire study.
Borisow, N., Paul, F., Ohlraun, S., Pach, D., Fischer, F. and Dörr, J.
PLoS ONE 9
(6): e99106.
5 June 2014
Comparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaques.
Bowles, E.J., Schiffner, T., Rosario, M., Needham, G.A., Ramaswamy, M., McGouran, J., Kessler, B., LaBranche, C., McMichael, A.J., Montefiori, D., Sattentau, Q.J., Hanke, T. and Stewart-Jones, G.B.E.
PLoS ONE 9
(12): e114709.
9 December 2014
Dynamic formation of macular microcysts independent of vitreous traction changes.
Brandt, A.U., Oberwahrenbrock, T., Kadas, E.M., Lagrèze, W.A. and Paul, F.
Neurology 83
(1): 73-77.
1 July 2014
Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α.
Brooke, M.A., Longhurst, H.J., Plagnol, V., Kirkby, N.S., Mitchell, J.A., Rüschendorf, F., Warner, T.D., Kelsell, D.P. and MacDonald, T.T.
Gut 63
(1): 96-104.
January 2014
Oxidative damage to mitochondria at the nodes of Ranvier precedes axon degeneration in ex vivo transected axons.
Bros, H., Millward, J.M., Paul, F., Niesner, R. and Infante-Duarte, C.
Experimental Neurology 261
(11): 127-135.
November 2014
Structure of the large ribosomal subunit from human mitochondria.
Brown, A., Amunts, A., Bai, X.C., Sugimoto, Y., Edwards, P.C., Murshudov, G., Scheres, S.H.W. and Ramakrishnan, V.
Science 346
(6210): 718-722.
7 November 2014
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.
Bruedigam, C., Bagger, F.O., Heidel, F.H., Paine Kuhn, C., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A.S., Lock, R.B., Bullinger, L., Hill, G.R., Armstrong, S.A., Williams, D.A. and Lane, S.W.
Cell Stem Cell 15
(6): 775-90.
4 December 2014
Mitochondrial function in pluripotent stem cells and cellular reprogramming.
Bukowiecki, R., Adjaye, J. and Prigione, A.
Gerontology 60
(2): 174-182.
February 2014
RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer.
Bunse, M., Bendle, G.M., Linnemann, C., Bies, L., Schulz, S., Schumacher, T.N. and Uckert, W.
Molecular Therapy 22
(11): 1983-1991.
November 2014
Chemically defined generation of human cardiomyocytes.
Burridge, P.W., Matsa, E., Shukla, P., Lin, Z.C., Churko, J.M., Ebert, A.D., Lan, F., Diecke, S., Huber, B., Mordwinkin, N.M., Plews, J.R., Abilez, O.J., Cui, B., Gold, J.D. and Wu, J.C.
Nature Methods 11
(8): 855-60.
August 2014
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
Butland, S.L., Sanders, S.S., Schmidt, M.E., Riechers, S.P., Lin, D.T.S., Martin, D.D.O., Vaid, K., Graham, R.K., Singaraja, R.R., Wanker, E.E., Conibear, E. and Hayden, M.R.
Human Molecular Genetics 23
(15): 4142-4160.
1 August 2014
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.
Cabezas-Wallscheid, N., Klimmeck, D., Hansson, J., Lipka, D.B., Reyes, A., Wang, Q., Weichenhan, D., Lier, A., von Paleske, L., Renders, S., Wünsche, P., Zeisberger, P., Brocks, D., Gu, L., Herrmann, C., Haas, S., Essers, M.A.G., Brors, B., Eils, R., Huber, W., Milsom, M.D., Plass, C., Krijgsveld, J. and Trumpp, A.
Cell Stem Cell 15
(4): 507-522.
2 October 2014
Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation.
Caglayan, S., Takagi-Niidome, S., Liao, F., Carlo, A.S., Schmidt, V., Burgert, T., Kitago, Y., Füchtbauer, E.M., Füchtbauer, A., Holtzman, D.M., Takagi, J. and Willnow, T.E.
Science Translational Medicine 6
(223): 223ra20.
12 February 2014
Gibbon genome and the fast karyotype evolution of small apes.
Carbone, L., Harris, R.A., Gnerre, S., Veeramah, K.R., Lorente-Galdos, B., Huddleston, J., Meyer, T.J., Herrero, J., Roos, C., Aken, B., Anaclerio, F., Archidiacono, N., Baker, C., Barrell, D., Batzer, M.A., Beal, K., Blancher, A., Bohrson, C.L., Brameier, M., Campbell, M.S., Capozzi, O., Casola, C., Chiatante, G., Cree, A., Damert, A., de Jong, P.J., Dumas, L., Fernandez-Callejo, M., Flicek, P., Fuchs, N.V., Gut, I., Gut, M., Hahn, M.W., Hernandez-Rodriguez, J., Hillier, L.W., Hubley, R., Ianc, B., Izsvák, Z., Jablonski, N.G., Johnstone, L.M., Karimpour-Fard, A., Konkel, M.K., Kostka, D., Lazar, N.H., Lee, S.L., Lewis, L.R., Liu, Y., Locke, D.P., Mallick, S., Mendez, F.L., Muffato, M., Nazareth, L.V., Nevonen, K.A., O'Bleness, M., Ochis, C., Odom, D.T., Pollard, K.S., Quilez, J., Reich, D., Rocchi, M., Schumann, G.G., Searle, S., Sikela, J.M., Skollar, G., Smit, A., Sonmez, K., ten Hallers, B., Terhune, E., Thomas, G.W.C., Ullmer, B., Ventura, M., Walker, J.A., Wall, J.D., Walter, L., Ward, M.C., Wheelan, S.J., Whelan, C.W., White, S., Wilhelm, L.J., Woerner, A.E., Yandell, M., Zhu, B., Hammer, M.F., Marques-Bonet, T., Eichler, E.E., Fulton, L., Fronick, C., Muzny, D.M., Warren, W.C., Worley, K.C., Rogers, J., Wilson, R.K. and Gibbs, R.A.
Nature 513
(7517): 195-201.
11 September 2014
Differences in cell-type-specific responses to angiotensin II explain cardiac remodeling differences in C57BL/6 mouse substrains.
Cardin, S., Scott-Boyer, M.P., Praktiknjo, S., Jeidane, S., Picard, S., Reudelhuber, T.L. and Deschepper, C.F.
Hypertension 64
(5): 1040-1046.
November 2014
Sorting receptor sortilin-a culprit in cardiovascular and neurological diseases.
Carlo, A.S., Nykjaer, A. and Willnow, T.E.
Journal of Molecular Medicine 92
(9): 905-911.
September 2014
The impact of self-reported childhood trauma on emotion regulation in borderline personality disorder and major depression.
Carvalho Fernando, S., Beblo, T., Schlosser, N., Terfehr, K., Otte, C., Loewe, B., Wolf, O.T., Spitzer, C., Driessen, M. and Wingenfeld, K.
Journal of Trauma & Dissociation 15
(4): 384-401.
30 June 2014
MicroRNA-133 modulates the β(1)-adrenergic receptor transduction cascade.
Castaldi, A., Zaglia, T., Di Mauro, V., Carullo, P., Viggiani, G., Borile, G., Di Stefano, B., Schiattarella, G.G., Gualazzi, M.G., Elia, L., Stirparo, G.G., Colorito, M.L., Pironti, G., Kunderfranco, P., Esposito, G., Bang, M.L., Mongillo, M., Condorelli, G. and Catalucci, D.
Circulation Research 115
(2): 273-283.
7 July 2014
Neurolysin knockout mice generation and initial phenotype characterization.
Cavalcanti, D.M.L.P., Castro, L.M., Rosa Neto, J.C., Seelaender, M., Neves, R.X., Oliveira, V., Forti, F.L., Iwai, L.K., Gozzo, F.C., Todiras, M., Schadock, I., Barros, C.C., Bader, M. and Ferro, E.S.
Journal of Biological Chemistry 289
(22): 15426-15440.
30 May 2014
Inhibition of c-Kit signaling is associated with reduced heat and cold pain sensitivity in humans.
Ceko, M., Milenkovic, N., Le Coutre, P., Westermann, J. and Lewin, G.R.
Pain 155
(7): 1222-1228.
July 2014
Recessive TTN truncating mutations define novel forms of core myopathy with heart disease.
Chauveau, C., Bonnemann, C.G., Julien, C., Kho, A.L., Marks, H., Talim, B., Maury, P., Arne-Bes, M.C., Uro-Coste, E., Alexandrovich, A., Vihola, A., Schafer, S., Kaufmann, B., Medne, L., Hübner, N., Foley, A.R., Santi, M., Udd, B., Topaloglu, H., Moore, S.A., Gotthardt, M., Samuels, M.E., Gautel, M. and Ferreiro, A.
Human Molecular Genetics 23
(4): 980-991.
15 February 2014
Role of TRPV1 channels in ischemia/reperfusion-induced acute kidney injury.
Chen, L., Markó, L., Kaßmann, M., Zhu, Y., Wu, K. and Gollasch, M.
PLoS ONE 9
(10): e109842.
17 October 2014
A patient with a floating kidney and nephrotic syndrome.
Choi, M., Schneider, W., Elitok, S., Luft, F.C. and Kettritz, R.
Clinical Nephrology 82
(2): 128-132.
August 2014
Ein Fall von schwebender Niere und nephrotischem Syndrom [A patient with a floating kidney and nephrotic syndrome].
Choi, M., Schneider, W., Elitok, S., Luft, F.C. and Kettritz, R.
Nieren- und Hochdruckkrankheiten 43
(10): 444-449.
August 2014
Quantitative-proteomic comparison of alpha and beta cells to uncover novel targets for lineage reprogramming.
Choudhary, A., He, K.H., Mertins, P., Udeshi, N.D., Dančík, V., Fomina-Yadlin, D., Kubicek, S., Clemons, P.A., Schreiber, S.L., Carr, S.A. and Wagner, B.K.
PLoS ONE 9
(4): e95194.
23 April 2014
Altered autonomic arousal in psychosis: an analysis of vulnerability and specificity.
Clamor, A., Hartmann, M.M., Koether, U., Otte, C., Moritz, S. and Lincoln, T.M.
Schizophrenia Research 154
(1-3): 73-78.
April 2014
Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1.
Cochella, L., Tursun, B., Hsieh, Y.W., Galindo, S., Johnston, R.J., Chuang, C.F. and Hobert, O.
Genes & Development 28
(1): 34-43.
1 January 2014
Overexpression of adenosine A2A receptors in rats: effects on depression, locomotion, and anxiety.
Coelho, J.E., Alves, P., Canas, P.M., Valadas, J.S., Shmidt, T., Batalha, V.L., Ferreira, D.G., Ribeiro, J.A., Bader, M., Cunha, R.A., do Couto, F.S. and Lopes, L.V.
Frontiers in Psychiatry 5
: 67.
13 June 2014
Characterization of neuromyelitis optica and neuromyelitis optica spectrum disorder patients with a late onset.
Collongues, N., Marignier, R., Jacob, A., Leite, M., Siva, A., Paul, F., Zephir, H., Akman-Demir, G., Elsone, L., Jarius, S., Papeix, C., Mutch, K., Saip, S., Wildemann, B., Kitley, J., Karabudak, R., Aktas, O., Kuscu, D., Altintas, A., Palace, J., Confavreux, C. and De Seze, J.
Multiple Sclerosis Journal 20
(8): 1086-1094.
2014
Skewed B cell differentiation affects lymphoid organogenesis but not T cell-mediated autoimmunity.
Colombo, E., Tentorio, P., Musio, S., Rajewsky, K., Pedotti, R., Casola, S. and Farina, C.
Clinical and Experimental Immunology 176
(1): 58-65.
April 2014
Highly resolved intravital striped-illumination microscopy of germinal centers.
Cseresnyes, Z., Oehme, L., Andresen, V., Sporbert, A., Hauser, A.E. and Niesner, R.
Journal of Visualized Experiments
(86): e51135.
9 April 2014
Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.
Curtis, D.J., Sood, A., Phillips, T.J., Leinster, V.H.L., Nishiguchi, A., Coyle, C., Lacharme-Lora, L., Beaumont, O., Kemp, H., Goodall, R., Cornes, L., Giugliano, M., Barone, R.A., Matsusaki, M., Akashi, M., Tanaka, H.Y., Kano, M., McGarvey, J., Halemani, N.D., Simon, K., Keehan, R., Ind, W., Masters, T., Grant, S., Athwal, S., Collett, G., Tannetta, D., Sargent, I.L., Scull-Brown, E., Liu, X., Aquilina, K., Cohen, N., Lane, J.D., Thoresen, M., Hanley, J., Randall, A. and Case, C.P.
Experimental Neurology 261
: 386-395.
November 2014
Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle.
Czajkowski, M.T., Rassek, C., Lenhard, D., Bröhl, D. and Birchmeier, C.
Developmental Biology 395
(2): 307-3016.
15 November 2014
Oxidative status imbalance in patients with metabolic syndrome: Role of the myeloperoxidase/hydrogen peroxide axis.
Da Fonseca, L.J.S., Nunes-Souza, V., Guedes, G.D.S., Schettino-Silva, G., Mota-Gomes, M.A. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2014
: 898501.
2014
RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.
Dahlmann, M., Okhrimenko, A., Marcinkowski, P., Osterland, M., Herrmann, P., Smith, J., Heizmann, C.W., Schlag, P.M. and Stein, U.
Oncotarget 5
(10): 3220-3233.
30 May 2014
Maintenance and neuronal differentiation of chicken induced pluripotent stem-like cells.
Dai, R., Rossello, R., Chen, C.C., Kessler, J., Davison, I., Hochgeschwender, U. and Jarvis, E.D.
Stem Cells International 2014
: 182737.
9 December 2014
Annexin A2 mediates apical trafficking of renal Na(+)-K(+)-2Cl(-)-cotransporter.
Dathe, C., Daigeler, A.L., Seifert, W., Jankowski, V., Mrowka, R., Kalis, R., Wanker, E., Mutig, K., Bachmann, S. and Paliege, A.
Journal of Biological Chemistry 289
(14): 9983-9997.
4 April 2014
Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.
Dawson, M.A., Gudgin, E.J., Horton, S.J., Giotopoulos, G., Meduri, E., Robson, S., Cannizzaro, E., Osaki, H., Wiese, M., Putwain, S., Fong, C.Y., Grove, C., Craig, J., Dittmann, A., Lugo, D., Jeffrey, P., Drewes, G., Lee, K., Bullinger, L., Prinjha, R.K., Kouzarides, T., Vassiliou, G.S. and Huntly, B.J.P.
Leukemia 28
(2): 311-320.
February 2014
Präeklampsie, das Herz und der Blutdruck [Preeclampsia, the heart and the blood pressure].
Dechend, R.
Diabetes, Stoffwechsel und Herz 23
(5): 292-293.
1 October 2014
GP130 activation induces myeloma and collaborates with MYC.
Dechow, T., Steidle, S., Götze, K.S., Rudelius, M., Behnke, K., Pechloff, K., Kratzat, S., Bullinger, L., Fend, F., Soberon, V., Mitova, N., Li, Z., Thaler, M., Bauer, J., Pietschmann, E., Albers, C., Grundler, R., Schmidt-Supprian, M., Ruland, J., Peschel, C., Duyster, J., Rose-John, S., Bassermann, F. and Keller, U.
Journal of Clinical Investigation 124
(12): 5263-5274.
1 December 2014
Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses.
Dejanovic, B., Semtner, M., Ebert, S., Lamkemeyer, T., Neuser, F., Luescher, B., Meier, J.C. and Schwarz, G.
PLoS Biology 12
(7): e1001908.
15 July 2014
Exonic microdeletions of the gephyrin gene impair GABAergic synaptic inhibition in patients with idiopathic generalized epilepsy.
Dejanovic, B., Lal, D., Catarino, C.B., Arjune, S., Belaidi, A.A., Trucks, H., Vollmar, C., Surges, R., Kunz, W.S., Motameny, S., Altmüller, J., Köhler, A., Neubauer, B.A., Nürnberg, P., Noachtar, S., Schwarz, G. and Sander, T.
Neurobiology of Disease 67
: 88-96.
July 2014
Hexosamine pathway metabolites enhance protein quality control and prolong life.
Denzel, M.S., Storm, N.J., Gutschmidt, A., Baddi, R., Hinze, Y., Jarosch, E., Sommer, T., Hoppe, T. and Antebi, A.
Cell 156
(6): 1167-1178.
13 March 2014
Besondere Bluthochdruckfälle: Leitlinienempfehlungen der European Society of Cardiology und European Society of Hypertension [Special cases of high blood pressure: Guideline recommendations of the European Society of Cardiology and European Society of Hypertension].
Derer, W. and Dechend, R.
Kardiologe 8
(5): 419-428.
October 2014
Behandlung der arteriellen Hypertonie - Aspekte der neuen europäischen Leitlinien [Treatment of arterial hypertension - Issues of the new european guidelines].
Derer, W., Dechend, R. and Baberg, H.
Klinikarzt 43
(3): 130-135.
March 2014
Cupulin is a zona pellucida-like domain protein and major component of the cupula from the inner ear.
Dernedde, J., Weise, C., Mueller, E.C., Hagiwara, A., Bachmann, S., Suzuki, M., Reutter, W., Tauber, R. and Scherer, H.
PLoS ONE 9
(11): e111917.
4 November 2014
Complement is activated by IgG hexamers assembled at the cell surface.
Diebolder, C.A., Beurskens, F.J., de Jong, R.N., Koning, R.I., Strumane, K., Lindorfer, M.A., Voorhorst, M., Ugurlar, D., Rosati, S., Heck, A.J.R., van de Winkel, J.G.J., Wilson, I.A., Koster, A.J., Taylor, R.P., Saphire, E.O., Burton, D.R., Schuurman, J., Gros, P. and Parren, P.W.H.I
Science 343
(6176): 1260-3.
14 March 2014
Second generation codon optimized minicircle (CoMiC) for nonviral reprogramming of human adult fibroblasts.
Diecke, S., Lisowski, L., Kooreman, N.G. and Wu, J.C.
Methods in Molecular Biology 1181
: 1-13.
1 January 2014
Rapid parametric mapping of the longitudinal relaxation time t1 using two-dimensional variable flip angle magnetic resonance imaging at 1.5 Tesla, 3 Tesla, and 7 Tesla.
Dieringer, M.A., Deimling, M., Santoro, D., Wuerfel, J., Madai, V.I., Sobesky, J., von Knobelsdorff-Brenkenhoff, F., Schulz-Menger, J. and Niendorf, T.
PLoS ONE 9
(3): e91318.
12 March 2014
Blood flow and Bmp signaling control endocardial chamber morphogenesis.
Dietrich, A.C., Lombardo, V.A., Veerkamp, J., Priller, F. and Abdelilah-Seyfried, S.
Developmental Cell 30
(4): 367-377.
25 August 2014
The biological actions of 11,12-epoxyeicosatrienoic acid in endothelial cells are specific to the R/S-enantiomer and require the G(s) protein.
Ding, Y., Froemel, T., Popp, R., Falck, J.R., Schunck, W.H. and Fleming, I.
Journal of Pharmacology and Experimental Therapeutics 350
(1): 14-21.
July 2014
Coffee intake and risk of type 2 diabetes: the Multiethnic Cohort.
Doo, T., Morimoto, Y., Steinbrecher, A., Kolonel, L.N. and Maskarinec, G.
Public Health Nutrition 17
(6): 1328-1336.
June 2014
Application of high-throughput sequencing for studying genomic variations in congenital heart disease.
Dorn, C., Grunert, M. and Sperling, S.R.
Briefings in Functional Genomics 13
(1): 51-65.
January 2014
Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1.
Doss, S., Brandt, A.U., Oberwahrenbrock, T., Endres, M., Paul, F. and Rinnenthal, J.L.
Cerebellum 13
(2): 199-206.
April 2014
High prevalence of NMDA receptor IgA/IgM antibodies in different dementia types.
Doss, S., Wandinger, K.P., Hyman, B.T., Panzer, J.A., Synofzik, M., Dickerson, B., Mollenhauer, B., Scherzer, C.R., Ivinson, A.J., Finke, C., Schöls, L., Müller vom Hagen, J., Trenkwalder, C., Jahn, H., Höltje, M., Biswal, B.B., Harms, L., Ruprecht, K., Buchert, R., Höglinger, G.U., Oertel, W.H., Unger, M.M., Körtvélyessy, P., Bittner, D., Priller, J., Spruth, E.J., Paul, F., Meisel, A., Lynch, D.R., Dirnagl, U., Endres, M., Teegen, B., Probst, C., Komorowski, L., Stöcker, W., Dalmau, J. and Pruess, H.
Annals of Clinical and Translational Neurology 1
(10): 822-832.
October 2014
Pulse pressure in children and adolescents with type 1 diabetes mellitus in Germany and Austria.
Dost, A., Molz, E., Krebs, A., Bechtold, S., Kapellen, T., Rohrer, T., Raile, K., Fritsch, M., Schwab, K.O. and Holl, R.
Pediatric Diabetes 15
(3): 236-243.
May 2014
Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders.
Dukart, J., Regen, F., Kherif, F., Colla, M., Bajbouj, M., Heuser, I., Frackowiak, R.S. and Draganski, B.
Proceedings of the National Academy of Sciences of the United States of America 111
(3): 1156-1161.
21 January 2014
High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.
Duncan, C.J.A., Williams, J.P., Schiffner, T., Gärtner, K., Ochsenbauer, C., Kappes, J., Russell, R.A., Frater, J. and Sattentau, Q.J.
Journal of Virology 88
(4): 2025-2034.
February 2014
7‐Tesla magnetic resonance imaging for brain iron quantification in homozygous and heterozygous PANK2 mutation carriers.
Dusek, P., Tovar Martinez, E.M., Madai, V.I., Jech, R., Sobesky, J., Paul, F., Niendorf, T., Wuerfel, J. and Schneider, S.A.
Movement Disorders Clinical Practice 1
(4): 329-335.
December 2014
Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta.
Dworatzek, E., Mahmoodzadeh, S., Schubert, C., Westphal, C., Leber, J., Kusch, A., Kararigas, G., Fliegner, D., Moulin, M., Ventura-Clapier, R., Gustafsson, J.A., Davidson, M.M., Dragun, D. and Regitz-Zagrosek, V.
Cardiovascular Research 102
(3): 418-428.
1 June 2014
Parasympathetic neurons originate from nerve-associated peripheral glial progenitors.
Dyachuk, V., Furlan, A., Shahidi, M.K., Giovenco, M., Kaukua, N., Konstantinidou, C., Pachnis, V., Memic, F., Marklund, U., Müller, T., Birchmeier, C., Fried, K., Ernfors, P. and Adameyko, I.
Science 345
(6192): 82-87.
4 July 2014
Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system.
Ebert, A.D., Kodo, K., Liang, P., Wu, H., Huber, B.C., Riegler, J., Churko, J., Lee, J., de Almeida, P., Lan, F., Diecke, S., Burridge, P.W., Gold, J.D., Mochly-Rosen, D. and Wu, J.C.
Science Translational Medicine 6
(255): 255ra130.
24 September 2014
Quantitative proteomic analysis of gene regulation by miR-34a and miR-34c.
Ebner, O.A. and Selbach, M.
PLoS ONE 9
(3): e92166.
17 March 2014
Increased cutaneous absorption reflects impaired barrier function of reconstructed skin models mimicking keratinisation disorders.
Eckl, K.M., Weindl, G., Ackermann, K., Küchler, S., Casper, R., Radowski, M.R., Haag, R., Hennies, H.C. and Schäfer-Korting, M.
Experimental Dermatology 23
(4): 286-288.
April 2014
Homozygous and compound-heterozygous mutations in TGDS cause Catel-Manzke syndrome.
Ehmke, N., Caliebe, A., Koenig, R., Kant, S.G., Stark, Z., Cormier-Daire, V., Wieczorek, D., Gillessen-Kaesbach, G., Hoff, K., Kawalia, A., Thiele, H., Altmüller, J., Fischer-Zirnsak, B., Knaus, A., Zhu, N., Heinrich, V., Huber, C., Harabula, I., Spielmann, M., Horn, D., Kornak, U., Hecht, J., Krawitz, P.M., Nürnberg, P., Siebert, R., Manzke, H. and Mundlos, S.
American Journal of Human Genetics 95
(6): 763-70.
4 December 2014
Flexible, polymer-supported synthesis of sphingosine derivatives provides ceramides with enhanced biological activity.
El-Dahshan, A., Al-Gharabli, S.I., Radetzki, S., Al-Tel, T.H., Kumar, P. and Rademann, J.
Bioorganic and Medicinal Chemistry 22
(19): 5506-5512.
1 October 2014
Deletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kinetics.
Elhamine, F., Radke, M., Pfitzer, G., Granzier, H., Gotthardt, M. and Stehle, R.
Journal of Cell Science 127
(Pt 17): 3666-3674.
1 September 2014
Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects.
Engeli, S., Lehmann, A.C., Kaminski, J., Haas, V., Janke, J., Zoerner, A.A., Luft, F.C., Tsikas, D. and Jordan, J.
Obesity 22
(5): E70-E76.
May 2014
Urinary CD4 T cells identify SLE patients with proliferative lupus nephritis and can be used to monitor treatment response.
Enghard, P., Rieder, C., Kopetschke, K., Klocke, J.R., Undeutsch, R., Biesen, R., Dragun, D., Gollasch, M., Schneider, U., Aupperle, K., Humrich, J.Y., Hiepe, F., Backhaus, M., Radbruch, A.H., Burmester, G.R. and Riemekasten, G.
Annals of the Rheumatic Diseases 73
(1): 277-283.
January 2014
IPG strip-based peptide fractionation for shotgun proteomics.
Eravci, M., Sommer, C. and Selbach, M.
Methods in Molecular Biology 1156
: 67-77.
2014
GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.
Fabian, J., Lodrini, M., Oehme, I., Schier, M.C., Thole, T.M., Hielscher, T., Kopp-Schneider, A., Opitz, L., Capper, D., von Deimling, A., Wiegand, I., Milde, T., Mahlknecht, U., Westermann, F., Popanda, O., Roels, F., Hero, B., Berthold, F., Fischer, M., Kulozik, A.E., Witt, O. and Deubzer, H.E.
Cancer Research 74
(9): 2604-2616.
1 May 2014
Protease inhibitor 15, a candidate gene for abdominal aortic internal elastic lamina ruptures in the rat.
Falak, S., Schafer, S., Baud, A., Hummel, O., Schulz, H., Gauguier, D., Hubner, N. and Osborne-Pellegrin, M.
Physiological Genomics 46
(12): 418-428.
15 June 2014
Polymerization, bending, tension: What happens at the leading edge of motile cells?
Falcke, M. and Zimmermann, J.
European Physical Journal - Special Topics 223
(7): 1353-1372.
June 2014
Early life stress modulates amygdala-prefrontal functional connectivity: implications for oxytocin effects.
Fan, Y., Herrera-Melendez, A.L., Pestke, K., Feeser, M., Aust, S., Otte, C., Pruessner, J.C., Boeker, H., Bajbouj, M. and Grimm, S.
Human Brain Mapping 35
(10): 5328-5339.
October 2014
Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
Fan, J., Ponferrada, V.G., Sato, T., Vemaraju, S., Fruttiger, M., Gerhardt, H., Ferrara, N. and Lang, R. A.
Development 141
(2): 448-459.
January 2014
Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets.
Farazi, T.A., Leonhardt, C.S., Mukherjee, N., Mihailovic, A., Li, S., Max, K.E.A., Meyer, C., Yamaji, M., Cekan, P., Jacobs, N.C., Gerstberger, S., Bognanni, C., Larsson, E., Ohler, U. and Tuschl, T.
RNA 20
(7): 1090-1102.
July 2014
Pre-diagnostic anthropometry and survival after colorectal cancer diagnosis in Western European populations.
Fedirko, V., Romieu, I., Aleksandrova, K., Pischon, T., Trichopoulos, D., Peeters, P.H., Romaguera-Bosch, D., Bueno-de-Mesquita, H.B., Dahm, C.C., Overvad, K., Chirlaque, M.D., Johansen, C., Bidstrup, P.E., Dalton, S.O., Gunter, M.J., Wark, P.A., Norat, T., Halkjaer, J., Tjønneland, A., Dik, V.K., Siersema, P.D., Boutron-Ruault, M.C., Dossus, L., Bastide, N., Kühn, T., Kaaks, R., Boeing, H., Trichopoulou, A., Klinaki, E., Katsoulis, M., Pala, V., Panico, S., Tumino, R., Palli, D., Vineis, P., Weiderpass, E., Skeie, G., González, C.A., Sánchez, M.J., Barricarte, A., Amiano, P., Quiros, J.R., Manjer, J., Jirström, K., Ljuslinder, I., Palmqvist, R., Khaw, K.T., Wareham, N., Bradbury, K.E., Stepien, M., Duarte-Salles, T., Riboli, E. and Jenab, M.
International Journal of Cancer 135
(8): 1949-1960.
15 October 2014
Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma.
Fehlker, M., Huska, M.R., Joens, T., Andrade-Navarro, M.A. and Kemmner, W.
BMC Cancer 14
(1): 64.
5 February 2014
Identification of Stim1 as a candidate gene for exaggerated sympathetic response to stress in the stroke-prone spontaneously hypertensive rat.
Ferdaus, M.Z., Xiao, B., Ohara, H., Nemoto, K., Harada, Y., Saar, K., Hübner, N., Isomura, M. and Nabika, T.
PLoS ONE 9
(4): e95091.
15 April 2014
Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids.
Fernandez-Cuesta, L., Peifer, M., Lu, X., Sun, R., Ozretić, L., Seidal, D., Zander, T., Leenders, F., George, J., Müller, C., Dahmen, I., Pinther, B., Bosco, G., Konrad, K., Altmüller, J., Nürnberg, P., Achter, V., Lang, U., Schneider, P.M., Bogus, M., Soltermann, A., Brustugun, O.T., Helland, Å., Solberg, S., Lund-Iversen, M., Ansén, S., Stoelben, E., Wright, G.M., Russell, P., Wainer, Z., Solomon, B., Field, J.K., Hyde, R., Davies, M.P., Heukamp, L.C., Petersen, I., Perner, S., Lovly, C., Cappuzzo, F., Travis, W.D., Wolf, J., Vingron, M., Brambilla, E., Haas, S.A., Buettner, R. and Thomas, R.K.
Nature Communications 5
: 3518.
27 March 2014
CD74–NRG1 fusions in lung adenocarcinoma.
Fernandez-Cuesta, L., Plenker, D., Osada, H., Sun, R., Menon, R., Leenders, F., Ortiz-Cuaran, S., Peifer, M., Bos, M., Daßler, J., Malchers, F., Schöttle, J., Vogel, W., Dahmen, I., Koker, M., Ullrich, R.T., Wright, G.M., Russell, P.A., Wainer, Z., Solomon, B., Brambilla, E., Nagy-Mignotte, H., Moro-Sibilot, D., Brambilla, C.G., Lantuejoul, S., Altmüller, J., Becker, C., Nürnberg, P., Heuckmann, J.M., Stoelben, E., Petersen, I., Clement, J.H., Sänger, J., Muscarella, L.A., la Torre, A., Fazio, V.M., Lahortiga, I., Perera, T., Ogata, S., Parade, M., Brehmer, D., Vingron, M., Heukamp, L.C., Buettner, R., Zander, T., Wolf, J., Perner, S., Ansén, S., Haas, S.A., Yatabe, Y. and Thomas, R.K.
Cancer Discovery 4
(4): 415-22.
1 April 2014
Haploinsufficiency of ETV6 and CDKN1B in patients with acute myeloid leukemia and complex karyotype.
Feurstein, S., Rücker, F.G., Bullinger, L., Hofmann, W., Manukjan, G., Göhring, G., Lehmann, U., Heuser, M., Ganser, A., Döhner, K., Schlegelberger, B. and Steinemann, D.
BMC Genomics 15
: 784.
11 September 2014
The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling.
Finsen, A.V., Ueland, T., Sjaastad, I., Ranheim, T., Ahmed, M.S., Dahl, C.P., Askevold, E.T., Aakhus, S., Husberg, C., Fiane, A.E., Lipp, M., Gullestad, L., Christensen, G., Aukrust, P. and Yndestad, A.
PLoS ONE 9
(11): e112172.
14 November 2014
Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway.
Fischer, R., Konkel, A., Mehling, H., Blossey, K., Gapelyuk, A., Wessel, N., von Schacky, C., Dechend, R., Muller, D.N., Rothe, M., Luft, F.C., Weylandt, K. and Schunck, W.H.
Journal of Lipid Research 55
(6): 1150-1164.
June 2014
Cardiotoxicity of mitoxantrone treatment in a german cohort of 639 multiple sclerosis patients.
Fleischer, V., Salmen, A., Kollar, S., Weyer, V., Siffrin, V., Chan, A., Zipp, F. and Luessi, F.
Journal of Clinical Neurology 10
(4): 289-295.
October 2014
Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a population-based study.
Floegel, A., Wientzek, A., Bachlechner, U., Jacobs, S., Drogan, D., Prehn, C., Adamski, J., Krumsiek, J., Schulze, M.B., Pischon, T. and Boeing, H.
International Journal of Obesity 38
(11): 1388-1396.
November 2014
Metagenomic insights into the human gut resistome and the forces that shape it.
Forslund, K., Sunagawa, S., Coelho, L.P. and Bork, P.
BioEssays 36
(3): 316-329.
March 2014
Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2.
Fortin, J., Boehm, U., Deng, C.X., Treier, M. and Bernard, D.J.
FASEB Journal 28
(8): 3396-3410.
August 2014
Development and evaluation of a short 24-h food list as part of a blended dietary assessment strategy in large-scale cohort studies.
Freese, J., Feller, S., Harttig, U., Kleiser, C., Linseisen, J., Fischer, B., Leitzmann, M.F., Six-Merker, J., Michels, K.B., Nimptsch, K., Steinbrecher, A., Pischon, T., Heuer, T., Hoffmann, I., Jacobs, G., Boeing, H. and Nöthlings, U.
European Journal of Clinical Nutrition 68
(3): 324-329.
March 2014
Interspecies differences in virus uptake versus cardiac function of the coxsackievirus and adenovirus receptor.
Freiberg, F., Sauter, M., Pinkert, S., Govindarajan, T., Kaldrack, J., Thakkar, M., Fechner, H., Klingel, K. and Gotthardt, M.
Journal of Virology 88
(13): 7345-7356.
1 July 2014
Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma.
Friesen, C., Hormann, I., Roscher, M., Fichtner, I., Alt, A., Hilger, R., Debatin, K.M. and Miltner, E.
Cell Cycle 13
(10): 1560-1570.
15 May 2014
Exome sequencing helped the fine diagnosis of two siblings afflicted with atypical Timothy syndrome (TS2).
Froehler, S., Kieslich, M., Langnick, C., Feldkamp, M., Opgen-Rhein, B., Berger, F., Will, J.C. and Chen, W.
BMC Medical Genetics 15
(1): 48.
29 April 2014
Simultaneous dual contrast weighting using double echo rapid acquisition with relaxation enhancement (RARE) imaging.
Fuchs, K., Hezel, F., Klix, S., Mekle, R., Wuerfel, J. and Niendorf, T.
Magnetic Resonance in Medicine 72
(6): 1590-1598.
December 2014
Quantifying the uncertainty in heritability.
Furlotte, N.A., Heckerman, D. and Lippert, C.
Journal of Human Genetics 59
(5): 269-275.
May 2014
Warped linear mixed models for the genetic analysis of transformed phenotypes.
Fusi, N., Lippert, C., Lawrence, N.D. and Stegle, O.
Nature Communications 5
: 4890.
19 September 2014
Intracellular glycine receptor function facilitates glioma formation in vivo.
Förstera, B., a Dzaye, O.D., Winkelmann, A., Semtner, M., Benedetti, B., Markovic, D.S., Synowitz, M., Wend, P., Fähling, M., Junier, M.P., Glass, R., Kettenmann, H. and Meier, J.C.
Journal of Cell Science 127
(Pt 17): 3687-3698.
1 September 2014
Effects of deep repetitive transcranial magnetic stimulation on brain-derived neurotrophic factor serum concentration in healthy volunteers.
Gaede, G., Hellweg, R., Zimmermann, H., Brandt, A.U., Dörr, J., Bellmann-Strobl, J., Zangen, A., Paul, F. and Pfueller, C.F.
Neuropsychobiology 69
(2): 112-119.
April 2014
Cortisol response to an experimental stress paradigm prospectively predicts long-term distress and resilience trajectories in response to active police service.
Galatzer-Levy, I.R., Steenkamp, M.M., Brown, A.D., Qian, M., Inslicht, S., Henn-Haase, C., Otte, C., Yehuda, R., Neylan, T.C. and Marmar, C.R.
Journal of Psychiatric Research 56
: 36-42.
September 2014
CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins.
Gao, J., Schatton, D., Martinelli, P., Hansen, H., Pla-Martin, D., Barth, E., Becker, C., Altmueller, J., Frommolt, P., Sardiello, M. and Rugarli, E.I.
Journal of Cell Biology 207
(2): 213-223.
27 October 2014
In vivo shRNA screens in solid tumors.
Gargiulo, G., Serresi, M., Cesaroni, M., Hulsman, D. and van Lohuizen, M.
Nature Protocols 9
(12): 2880-2902.
December 2014
Genetic deletion in uncoupling protein 3 augments (18)F-fluorodeoxyglucose cardiac uptake in the ischemic heart.
Gargiulo, S., Petretta, M.P., Greco, A., Panico, M., Larobina, M., Gramanzini, M., Schiattarella, G.G., Esposito, G., Petretta, M., Brunetti, A. and Cuocolo, A.
BMC Cardiovascular Disorders 14
: 98.
8 August 2014
Similarity in targets with REST points to neural and glioblastoma related miRNAs.
Gebhardt, M.L., Reuter, S., Mrowka, R. and Andrade-Navarro, M.A.
Nucleic Acids Research 42
(9): 5436-5446.
14 May 2014
Alkemio: association of chemicals with biomedical topics by text and data mining.
Gijon-Correas, J.A., Andrade-Navarro, M.A. and Fontaine, J.F.
Nucleic Acids Research 42
(W1): W422-W429.
1 July 2014
circBase: a database for circular RNAs.
Glažar, P., Papavasileiou, P. and Rajewsky, N.
RNA 20
(11): 1666-1670.
November 2014
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.
Glerup, S., Olsen, D., Vaegter, C.B., Gustafsen, C., Sjoegaard, S.S., Hermey, G., Kjolby, M., Molgaard, S., Ulrichsen, M., Boggild, S., Skeldal, S., Fjorback, A.N., Nyengaard, J.R., Jacobsen, J., Bender, D., Bjarkam, C.R., Sørensen, E.S., Füchtbauer, E.M., Eichele, G., Madsen, P., Willnow, T.E., Petersen, C.M. and Nykjaer, A.
Neuron 82
(5): 1074-87.
4 June 2014
Axon guidance factor Slit2 inhibits neural invasion and metastasis in pancreatic cancer.
Goehrig, A., Detjen, K.M., Hilfenhaus, G., Koerner, J., Welzel, M., Arsenic, R., Schmuck, R., Bahra, M., Wu, J.Y., Wiedenmann, B. and Fischer, C.
Cancer Research 74
(5): 1529-1540.
1 March 2014
Manufacture of gene modified human T cells with a memory stem/ central memory phenotype.
Gomez-Eerland, R., Nuijen, B., Heemskerk, B., van Rooij, N., van den Berg, J.H., Beijnen, J.H., Uckert, W., Kvistborg, P., Schumacher, T., Haanen, J.B.A.G. and Jorritsma, A.
Human Gene Therapy Methods 25
(5): 277-287.
October 2014
Chlamydia infection depends on a functional MDM2-p53 axis.
Gonzalez, E., Rother, M., Kerr, M.C., Al-Zeer, M.A., Abu-Lubad, M., Kessler, M., Brinkmann, V., Loewer, A. and Meyer, T.F.
Nature Communications 5
: 5201.
13 November 2014
In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
Gouti, M., Tsakiridis, A., Wymeersch, F.J., Huang, Y., Kleinjung, J., Wilson, V. and Briscoe, J.
PLoS Biology 12
(8): e1001937.
26 August 2014
Ophthalmic magnetic resonance imaging at 7.0 T using a 6-channel transceiver radiofrequency coil array in healthy subjects and patients with intraocular masses.
Graessl, A., Muhle, M., Schwerter, M., Rieger, J., Oezerdem, C., Santoro, D., Lysiak, D., Winter, L., Hezel, F., Waiczies, S., Guthoff, R.F., Falke, K., Hosten, N., Hadlich, S., Krueger, P.C., Langner, S., Stachs, O. and Niendorf, T.
Investigative Radiology 49
(5): 260-270.
May 2014
Modular 32-channel transceiver coil array for cardiac MRI at 7.0T.
Graessl, A., Renz, W., Hezel, F., Dieringer, M.A., Winter, L., Oezerdem, C., Rieger, J., Kellman, P., Santoro, D., Lindel, T.D., Frauenrath, T., Pfeiffer, H. and Niendorf, T.
Magnetic Resonance in Medicine 72
(1): 276-290.
July 2014
Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP.
Gray, E.J., Petsalaki, E., James, D.A., Bagshaw, R.D., Stacey, M.M., Rocks, O., Gingras, A.C. and Pawson, T.
Journal of Biological Chemistry 289
(51): 35397-35408.
19 December 2014
MOV10 is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.
Gregersen, L.H., Schueler, M., Munschauer, M., Mastrobuoni, G., Chen, W., Kempa, S., Dieterich, C. and Landthaler, M.
Molecular Cell 54
(4): 573-585.
22 May 2014
Unambiguous identification of miRNA:target site interactions by different types of ligation reactions.
Grosswendt, S., Filipchyk, A., Manzano, M., Klironomos, F., Schilling, M., Herzog, M., Gottwein, E. and Rajewsky, N.
Molecular Cell 54
(6): 1042-1054.
19 June 2014
Lipid accumulation in dysferlin-deficient muscles.
Grounds, M.D., Terrill, J., Radley-Crabb, H., Robertson, T., Papadimitriou, J., Spuler, S. and Shavlakadze, T.
American Journal of Pathology 184
(6): 1668-1676.
June 2014
Rare and private variations in neural crest, apoptosis and sarcomere genes define the polygenic background of isolated Tetralogy of Fallot.
Grunert, M., Dorn, C., Schueler, M., Dunkel, I., Schlesinger, J., Mebus, S., Alexi-Meskishvili, V., Perrot, A., Wassilew, K., Timmermann, B., Hetzer, R., Berger, F. and Sperling, S.R.
Human Molecular Genetics 23
(12): 3115-3128.
15 June 2014
Conservation of mRNA and protein expression during development of C. elegans.
Grün, D., Kirchner, M., Thierfelder, N., Stoeckius, M., Selbach, M. and Rajewsky, N.
Cell Reports 6
(3): 565-577.
13 February 2014
Relaxin does not improve angiotensin II-induced target-organ damage.
Haase, N., Rugor, J., Przybyl, L., Qadri, F., Müller, D.N. and Dechend, R.
PLoS ONE 9
(4): e93743.
7 April 2014
Neutralization of pathogenic beta1-receptor autoantibodies by aptamers in vivo: the first successful proof of principle in spontaneously hypertensive rats.
Haberland, A., Wallukat, G., Berg, S., Schulz, A.M., Freyse, E.J., Vetter, R., Salzsieder, E., Mueller, J., Kreutz, R. and Schimke, I.
Molecular and Cellular Biochemistry 393
(1-2): 177-180.
August 2014
Two independent transcription initiation codes overlap on vertebrate core promoters.
Haberle, V., Li, N., Hadzhiev, Y., Plessy, C., Previti, C., Nepal, C., Gehrig, J., Dong, X., Akalin, A., Suzuki, A.M., van IJcken, W.F.J., Armant, O., Ferg, M., Strähle, U., Carninci, P., Müller, F. and Lenhard, B.
Nature 507
(7492): 381-385.
20 March 2014
Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells.
Halvorsen, B., Dahl, T.B., Smedbakken, L.M., Singh, A., Michelsen, A.E., Skjelland, M., Krohg-Sørensen, K., Russell, D., Höpken, U.E., Lipp, M., Damås, J.K., Holm, S., Yndestad, A., Biessen, E.A. and Aukrust, P.
Cardiovascular Research 102
(1): 148-156.
1 April 2014
Eco-evolutionary dynamics of complex social strategies in microbial communities.
Harrington, K.I. and Sanchez, A.
Communicative & Integrative Biology 7
(1): e28230.
25 February 2014
Water-induced finger wrinkles do not affect touch acuity or dexterity in handling wet objects.
Haseleu, J., Omerbašić, D., Frenzel, H., Gross, M. and Lewin, G.R.
PLoS ONE 9
(1): e84949.
8 January 2014
Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation.
Heinig, K., Gätjen, M., Grau, M., Stache, V., Anagnostopoulos, I., Gerlach, K., Niesner, R.A., Cseresnyes, Z., Hauser, A.E., Lenz, P., Hehlgans, T., Brink, R., Westermann, J., Dörken, B., Lipp, M., Lenz, G., Rehm, A. and Höpken, U.E.
Cancer Discovery 4
: 1448-1465.
December 2014
Disruption of vascular Ca2+-activated chloride currents lowers blood pressure.
Heinze, C., Seniuk, A., Sokolov, M.V., Huebner, A.K., Klementowicz, A.E., Szijártó, I.A., Schleifenbaum, J., Vitzthum, H., Gollasch, M., Ehmke, H., Schroeder, B.C. and Hübner, C.A.
Journal of Clinical Investigation 124
(2): 675-686.
3 February 2014
Cytogenetic risk grouping by the monosomal karyotype classification is superior in predicting the outcome of acute myeloid leukemia undergoing allogeneic stem cell transplantation in complete remission.
Hemmati, P.G., Schulze-Luckow, A., Terwey, T.H., le Coutre, P., Vuong, L.G., Doerken, B. and Arnold, R.
European Journal of Haematology 92
(2): 102-110.
February 2014
HEK293-based production platform for γ-retroviral (SIN-) vectors: application for safe and efficient transfer of COL7A1 cDNA.
Hennig, K., Raasch, L., Kolbe, C., Weidner, S., Leisegang, M., Uckert, W., Titeux, M., Hovnanian, A., Kuehlcke, K. and Loew, R.
Human Gene Therapy Clinical Development 25
(4): 218-228.
December 2014
p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8(+) T cells.
Henson, S.M., Lanna, A., Riddell, N.E., Franzese, O., Macaulay, R., Griffiths, S.J., Puleston, D.J., Watson, A.S., Simon, A.K., Tooze, S.A. and Akbar, A.N.
Journal of Clinical Investigation 124
(9): 4004-4016.
2 September 2014
Transitory dasatinib-resistant states in KIT(mut) t(8;21) acute myeloid leukemia cells correlate with altered KIT expression.
Herrmann, M.D., Lennerz, J.K., Bullinger, L., Bartholomae, S., Holzmann, K., Westhoff, M.A., Corbacioglu, S. and Debatin, K.M.
Experimental Hematology 42
(2): 90-100.
February 2014
Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.
Heuberger, J., Kosel, F., Qi, J., Grossmann, K.S., Rajewsky, K. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 111
(9): 3472-3477.
4 March 2014
LotuS: an efficient and user-friendly OTU processing pipeline.
Hildebrand, F., Tito, R.Y., Voigt, A.Y., Bork, P. and Raes, J.
Microbiome 2
(1): 30.
30 September 2014
MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.
Hinkel, R., Trenkwalder, T., Petersen, B., Husada, W., Gesenhues, F., Lee, S., Hannappel, E., Bock-Marquette, I., Theisen, D., Leitner, L., Boekstegers, P., Cierniewski, C., Mueller, O.J., le Noble, F., Adams, R.H., Weinl, C., Nordheim, A., Reichart, B., Weber, C., Olson, E., Posern, G., Deindl, E., Niemann, H. and Kupatt, C.
Nature Communications 5
: 3970.
9 June 2014
Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation.
Hirt, M.N., Boeddinghaus, J., Mitchell, A., Schaaf, S., Boernchen, C., Müller, C., Schulz, H., Hubner, N., Stenzig, J., Stoehr, A., Neuber, C., Eder, A., Luther, P.K., Hansen, A. and Eschenhagen, T.
Journal of Molecular and Cellular Cardiology 74
: 151-161.
September 2014
Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction.
Hoegg-Beiler, M.B., Sirisi, S., Orozco, I.J., Ferrer, I., Hohensee, S., Auberson, M., Goedde, K., Vilches, C., de Heredia, M.L., Nunes, V., Estévez, R. and Jentsch, T.J.
Nature Communications 5
: 3475.
19 March 2014
Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma.
Hoellein, A., Fallahi, M., Schoeffmann, S., Steidle, S., Schaub, F.X., Rudelius, M., Laitinen, I., Nilsson, L., Goga, A., Peschel, C., Nilsson, J.A., Cleveland, J.L. and Keller, U.
Blood 124
(13): 2081-2090.
25 September 2014
Tracking of metabolic control from childhood to young adulthood in type 1 diabetes.
Hofer, S.E., Raile, K., Froehlich-Reiterer, E., Kapellen, T., Dost, A., Rosenbauer, J., Grulich-Henn, J. and Holl, R.W.
Journal of Pediatrics 165
(5): 956-961.e2.
November 2014
The Transformer database: biotransformation of xenobiotics.
Hoffmann, M.F., Preissner, S.C., Nickel, J., Dunkel, M., Preissner, R. and Preissner, S.
Nucleic Acids Research 42
(1): D1113-D1117.
1 January 2014
B-cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.
Hojer, C., Frankenberger, S., Strobl, L.J., Feicht, S., Djermanovic, K., Jagdhuber, F., Hömig-Hölzel, C., Ferch, U., Ruland, J., Rajewsky, K. and Zimber-Strobl, U.
Cancer Research 74
(16): 4318-4328.
15 August 2014
Curriculum Kardiale Magnetresonanztomographie (CMR) [Curriculum cardiac magnetic resonance (CMR) imaging].
Hombach, V., Kelle, S., Gebker, R., Nagel, E., Thiele, H., Schulz-Menger, J., Bruder, O., Fleck, E. and Katus, H.A.
Kardiologe 8
(6): 451-461.
2 December 2014
The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.
Hooli, B.V., Parrado, A.R., Mullin, K., Yip, W.K., Liu, T., Roehr, J.T., Qiao, D., Jessen, F., Peters, O., Becker, T., Ramirez, A., Lange, C., Bertram, L. and Tanzi, R.E.
Neurology 83
(15): 1353-1358.
7 October 2014
Glioma-associated microglial MMP9 expression is upregulated by TLR2 signaling and sensitive to minocycline.
Hu, F., Ku, M.C., Markovic, D., a Dzaye, O.D., Lehnardt, S., Synowitz, M., Wolf, S.A. and Kettenmann, H.
International Journal of Cancer 135
(11): 2569-2578.
December 2014
PCR duplication: a one-step cloning-free method to generate duplicated chromosomal loci and interference-free expression reporters in yeast.
Huber, F., Meurer, M., Bunina, D., Kats, I., Maeder, C.I., Stefl, M., Mongis, C. and Knop, M.
PLoS ONE 9
(12): e114590.
10 December 2014
Adeno-associated virus type 2 wild-type and vector-mediated genomic integration profiles of human diploid fibroblasts analyzed by third-generation PacBio DNA sequencing.
Hueser, D., Gogol-Doering, A., Chen, W. and Heilbronn, R.
Journal of Virology 88
(19): 11253-11263.
1 October 2014
iCLIP: protein-RNA interactions at nucleotide resolution.
Huppertz, I., Attig, J., D'Ambrogio, A., Easton, L.E., Sibley, C.R., Sugimoto, Y., Tajnik, M., König, J. and Ule, J.
Methods 65
(3): 274-87.
February 2014
Mutations in CKAP2L, the human homolog of the mouse Radmis gene, cause Filippi syndrome.
Hussain, M.S., Battaglia, A., Szczepanski, S., Kaygusuz, E., Toliat, M.R., Sakakibara, S., Altmüller, J., Thiele, H., Nürnberg, G., Moosa, S., Yigit, G., Beleggia, F., Tinschert, S., Clayton-Smith, J., Vasudevan, P., Urquhart, J.E., Donnai, D., Fryer, A., Percin, F., Brancati, F., Dobbie, A., Smigiel, R., Gillessen-Kaesbach, G., Wollnik, B., Noegel, A.A., Newman, W.G. and Nürnberg, P.
American Journal of Human Genetics 95
(5): 622-632.
6 November 2014
Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy.
Hähnel, P.S., Enders, B., Sasca, D., Roos, W.P., Kaina, B., Bullinger, L., Theobald, M. and Kindler, T.
Blood 123
(15): 2355-2366.
10 April 2014
Identification of importin alpha 7 specific transport cargoes using a proteomic screening approach.
Hügel, S., Depping, R., Dittmar, G., Rother, F., Cabot, R., Sury, M.D., Hartmann, E. and Bader, M.
Molecular & Cellular Proteomics 13
(5): 1286-1298.
1 May 2014
Phenotype of mice with inducible ablation of GluA1 AMPA receptors during late adolescence: Relevance for mental disorders.
Inta, D., Vogt, M.A., Elkin, H., Weber, T., Lima-Ojeda, J.M., Schneider, M., Luoni, A., Riva, M.A., Gertz, K., Hellmann-Regen, J., Kronenberg, G., Meyer-Lindenberg, A., Sprengel, R. and Gass, P.
Hippocampus 24
(4): 424-435.
April 2014
Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons.
Ivics, Z., Garrels, W., Mátés, L., Yau, T.Y., Bashir, S., Zidek, V., Landa, V., Geurts, A., Pravenec, M., Rülicke, T., Kues, W.A. and Izsvák, Z.
Nature Protocols 9
(4): 810-827.
April 2014
Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons.
Ivics, Z., Hiripi, L., Hoffmann, O.I., Mátés, L., Yau, T.Y., Bashir, S., Zidek, V., Landa, V., Geurts, A., Pravenec, M., Rülicke, T., Bösze, Z. and Izsvák, Z.
Nature Protocols 9
(4): 794-809.
April 2014
Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons.
Ivics, Z., Mátés, L., Yau, T.Y., Landa, V., Zidek, V., Bashir, S., Hoffmann, O.I., Hiripi, L., Garrels, W., Kues, W.A., Boesze, Z., Geurts, A., Pravenec, M., Rülicke, T. and Izsvák, Z.
Nature Protocols 9
(4): 773-793.
April 2014
Caspase-1 cleavage of the TLR adaptor TRIF inhibits autophagy and β-interferon production during Pseudomonas aeruginosa infection.
Jabir, M.S., Ritchie, N.D., Li, D., Bayes, H.K., Tourlomousis, P., Puleston, D., Lupton, A., Hopkins, L., Simon, A.K., Bryant, C. and Evans, T.J.
Cell Host & Microbe 15
(2): 214-227.
12 February 2014
Evaluation of various biomarkers as potential mediators of the association between coffee consumption and incident type 2 diabetes in the EPIC-Potsdam Study.
Jacobs, S., Kröger, J., Floegel, A., Boeing, H., Drogan, D., Pischon, T., Fritsche, A., Prehn, C., Adamski, J., Isermann, B., Weikert, C. and Schulze, M.B.
American Journal of Clinical Nutrition 100
(3): 891-900.
September 2014
Evidence for the interaction of Endophilin A3 with endogenous K(Ca)2.3 channels in PC12 cells.
Janbein, M., Quader, M.A., Hoppner, A.C., Grüner, I., Wanker, E., Wälter, S., Küppers, E., Grissmer, S. and Jäger, H.
Cellular Physiology and Biochemistry 34
(2): 474-490.
30 July 2014
Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate.
Jarius, S., Paul, F., Fechner, K., Ruprecht, K., Kleiter, I., Franciotta, D., Ringelstein, M., Pache, F., Aktas, O. and Wildemann, B.
Journal of Neuroinflammation 11
(1): 129.
29 July 2014
Clinical, paraclinical and serological findings in Susac syndrome: an international multicenter study.
Jarius, S., Kleffner, I., Dörr, J.M., Sastre-Garriga, J., Illes, Z., Eggenberger, E., Chalk, C., Ringelstein, M., Aktas, O., Montalban, X., Fechner, K., Stöcker, W., Ringelstein, E.B., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 11
: 46.
8 March 2014
Adenosine (A)2A receptor modulation of nicotine-induced locomotor sensitization: a pharmacological and transgenic approach.
Jastrzebska, J., Nowak, E., Smaga, I., Bystrowska, B., Frankowska, M., Bader, M., Filip, M. and Fuxe, K.
Neuropharmacology 81
: 318-326.
June 2014
Influence of comorbidity, age and performance status on treatment efficacy and safety of cetuximab plus irinotecan in irinotecan-refractory elderly patients with metastatic colorectal cancer.
Jehn, C.F., Böning, L., Kröning, H., Pezzutto, A. and Lüftner, D.
European Journal of Cancer 50
(7): 1269-1275.
May 2014
Cortical fosGFP expression reveals broad receptive field excitatory neurons targeted by POm.
Jouhanneau, J.S., Ferrarese, L., Estebanez, L., Audette, N.J., Brecht, M., Barth, AL. and Poulet, J.F.A.
Neuron 84
(5): 1065-1078.
3 December 2014
Bioimage informatics in the context of drosophila research.
Jug, F., Pietzsch, T., Preibisch, S. and Tomancak, P.
Methods 68
(1): 60-73.
15 June 2014
Optimal joint segmentation and tracking of escherichia coli in the mother machine.
Jug, F., Pietzsch, T., Kainmüller, D., Funke, J., Kaiser, M., van Nimwegen, E., Rother, C. and Myers, G.
Lecture Notes in Computer Science 8677
: 25-36.
2014
A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.
Junker, J.P., Peterson, K.A., Nishi, Y., Mao, J., McMahon, A.P. and van Oudenaarden, A.
Developmental Cell 31
(4): 448-460.
24 November 2014
Genome-wide RNA tomography in the zebrafish embryo.
Junker, J.P., Noël, E.S., Guryev, V., Peterson, K.A., Shah, G., Huisken, J., McMahon, A.P., Berezikov, E., Bakkers, J. and van Oudenaarden, A.
Cell 159
(3): 662-675.
23 October 2014
JAK2 V617F allele burden quantified by real time quantitative polymerase chain reaction and competitive polymerase chain reaction in patients with chronic myeloproliferative neoplasia.
Kaeda, J., Bonamino, M., Ayres-Silva, J., Solza, C., Ringel, F., Blau, O., Daumas, A., Oberender, C., Doerken, B., Le Coutre, P. and Zalcberg, I.
Leukemia & Lymphoma 55
(1): 128-135.
January 2014
Active graph matching for automatic joint segmentation and annotation of C. elegans.
Kainmueller, D., Jug, F., Rother, C. and Myers, G.
Lecture Notes in Computer Science 8673
: 81-88.
2014
Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.
Kanda, S., Tanigawa, S., Ohmori, T., Taguchi, A., Kudo, K., Suzuki, Y., Sato, Y., Hino, S., Sander, M., Perantoni, A.O., Sugano, S., Nakao, M. and Nishinakamura, R.
Journal of the American Society of Nephrology 25
(11): 2584-95.
November 2014
Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia.
Kasim, M., Benko, E., Winkelmann, A., Mrowka, R., Staudacher, J.J., Persson, P.B., Scholz, H., Meier, J.C. and Fahling, M.
Journal of Biological Chemistry 289
(39): 26973-26988.
26 September 2014
IL-21 is a central memory T cell-associated cytokine that inhibits the generation of pathogenic Th1/17 effector cells.
Kastirr, I., Maglie, S., Paroni, M., Alfen, J.S., Nizzoli, G., Sugliano, E., Crosti, M.C., Moro, M., Steckel, B., Steinfelder, S., Stölzel, K., Romagnani, C., Botti, F., Caprioli, F., Pagani, M., Abrignani, S. and Geginat, J.
Journal of Immunology 193
(7): 3322-3331.
1 October 2014
Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.
Kayatekin, C., Matlack, K.E.S., Hesse, W.R., Guan, Y., Chakrabortee, S., Russ, J., Wanker, E.E., Shah, J.V. and Lindquist, S.
Proceedings of the National Academy of Sciences of the United States of America 111
(33): 12085-12090.
19 August 2014
CYP-13A12 of the nematode Caenorhabditis elegans is a PUFA-epoxygenase involved in behavioural response to reoxygenation.
Keller, J., Ellieva, A., Ma, D.K., Ju, J., Nehk, E., Konkel, A., Falck, J.R., Schunck, W.H. and Menzel, R.
Biochemical Journal 464
(1): 61-71.
15 November 2014
Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencing.
Keller, A., Leidinger, P., Steinmeyer, F., Stähler, C., Franke, A., Hemmrich-Stanisak, G., Kappel, A., Wright, I., Dörr, J., Paul, F., Diem, R., Tocariu-Krick, B., Meder, B., Backes, C., Meese, E. and Ruprecht, K.
Multiple Sclerosis Journal 20
(3): 295-303.
March 2014
Serinproteasen und Komplement bei der ANCA-Vaskulitis [Serine proteases and complement in ANCA vasculitis].
Kettritz, R.
Nieren- und Hochdruckkrankheiten 43
(8): 373-377.
August 2014
A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family.
Khan, M.A., Rupp, V.M., Orpinell, M., Hussain, M.S., Altmüller, J., Steinmetz, M.O., Enzinger, C., Thiele, H., Höhne, W., Nürnberg, G., Baig, S.M., Ansar, M., Nürnberg, P., Vincent, J.B., Speicher, M.R., Gönczy, P. and Windpassinger, C.
Human Molecular Genetics 23
(22): 5940-5949.
15 November 2014
A method for the generation of TCR retrogenic mice.
Kieback, E., Hilgenberg, E. and Fillatreau, S.
Methods in Molecular Biology 1193
: 117-126.
2014
Discrete Notch signaling requirements in the specification of hematopoietic stem cells.
Kim, A.D., Melick, C.H., Clements, W.K., Stachura, D.L., Distel, M., Panáková, D., MacRae, C., Mork, L.A., Crump, J.G. and Traver, D.
EMBO Journal 33
(20): 2363-2373.
16 October 2014
Direct infusion mass spectrometry metabolomics dataset: a benchmark for data processing and quality control.
Kirwan, J.A., Weber, R.J.M., Broadhurst, D.I. and Viant, M.R.
Scientific Data 1
: 140012.
10 June 2014
Effect of specific psychotherapy for chronic depression on neural Responses to emotional faces.
Klein, J.P., Becker, B., Hurlemann, R., Scheibe, C., Colla, M. and Heuser, I.
Journal of Affective Disorders 166
: 93-97.
September 2014
Who and what drove Walter Kempner? The rice diet revisited.
Klemmer, P., Grim, C.E. and Luft, F.C.
Hypertension 64
(4): 684-688.
October 2014
Accelerated fast spin-echo magnetic resonance imaging of the heart using a self-calibrated split-echo approach.
Klix, S., Hezel, F., Fuchs, K., Ruff, J., Dieringer, M.A. and Niendorf, T.
PLoS ONE 9
(4): e94654.
11 April 2014
Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector.
Kobelt, D., Aumann, J., Schmidt, M., Wittig, B., Fichtner, I., Behrens, D., Lemm, M., Freundt, G., Schlag, P.M. and Walther, W.
Molecular Oncology 8
(3): 609-619.
May 2014
Long term recovery in critical illness myopathy is complete, contrary to polyneuropathy.
Koch, S., Wollersheim, T., Bierbrauer, J., Haas, K., Mörgeli, R., Deja, M., Spies, C.D., Spuler, S., Krebs, M. and Weber-Carstens, S.
Muscle & Nerve 50
(3): 431-436.
September 2014
Excision efficiency is not strongly coupled to transgenic rate: cell type dependent transposition efficiency of Sleeping Beauty and piggyBac DNA transposons.
Kolacsek, O., Erdei, Z., Apáti, A., Sándor, S., Izsvák, Z., Ivics, Z., Sarkadi, B. and Orbán, T.I.
Human Gene Therapy Methods 25
(4): 241-252.
August 2014
Disturbed function of the blood-cerebrospinal fluid barrier aggravates neuro-inflammation.
Kooij, G., Kopplin, K., Blasig, R., Stuiver, M., Koning, N., Goverse, G., van der Pol, S.M.A., van het Hof, B., Gollasch, M., Drexhage, J.A.R., Reijerkerk, A., Meij, I.C., Mebius, R., Willnow, T.E., Müller, D., Blasig, I.E. and de Vries, H.E.
Acta Neuropathologica 128
(2): 267-277.
August 2014
Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1.
Kozlenkov, A., Lapatsina, L., Lewin, G.R. and Smith, E.S.J.
Journal of Physiology 592
(Pt 4): 557-569.
15 February 2014
R-split-CHOP chemotherapy for elderly patients with diffuse large B-cell lymphoma.
Kreher, S., Lammer, F., Augustin, D., Pezzutto, A. and Baldus, C.D.
European Journal of Haematology 93
(1): 70-76.
July 2014
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher, S., Bouhlel, M.A., Cauchy, P., Lamprecht, B., Li, S., Grau, M., Hummel, F., Köchert, K., Anagnostopoulos, I., Jöhrens, K., Hummel, M., Hiscott, J., Wenzel, S.S., Lenz, P., Schneider, M., Küppers, R., Scheidereit, C., Giefing, M., Siebert, R., Rajewsky, K., Lenz, G., Cockerill, P.N., Janz, M., Dörken, B., Bonifer, C. and Mathas, S.
Proceedings of the National Academy of Sciences of the United States of America 111
(42): E4513-E4522.
21 October 2014
Brainstem manifestations in neuromyelitis optica: a multicenter study of 258 patients.
Kremer, L., Mealy, M., Jacob, A., Nakashima, I., Cabre, P., Bigi, S., Paul, F., Jarius, S., Aktas, O., Elsone, L., Mutch, K., Levy, M., Takai, Y., Collongues, N., Banwell, B., Fujihara, K. and de Seze, J.
Multiple Sclerosis Journal 20
(7): 843-847.
June 2014
Identical lesion morphology in primary progressive and relapsing-remitting MS -an ultrahigh field MRI study.
Kuchling, J., Ramien, C., Bozin, I., Dörr, J., Harms, L., Rosche, B., Niendorf, T., Paul, F., Sinnecker, T. and Wuerfel, J.
Multiple Sclerosis Journal 20
(14): 1866-1871.
December 2014
The ultrastructure of Chlorobaculum tepidum revealed by cryo-electron tomography.
Kudryashev, M., Aktoudianaki, A., Dedoglou, D., Stahlberg, H. and Tsiotis, G.
Biochimica et Biophysica Acta - Bioenergetics 1837
(10): 1635-1642.
October 2014
Occurrence of giant focal forms of congenital hyperinsulinism with incorrect visualization by (18)F DOPA-PET/CT scanning.
Kuehnen, P., Matthae, R., Arya, V., Hauptmann, K., Rothe, K., Waechter, S., Singer, M., Mohnike, W., Eberhard, T., Raile, K., Lauffer, L.M., Iakoubov, R., Hussain, K. and Blankenstein, O.
Clinical Endocrinology 81
(6): 847-854.
December 2014
Identification of PENDRIN (SLC26A4) mutations in patients with congenital hypothyroidism and "apparent" thyroid dysgenesis.
Kuehnen, P., Turan, S., Froehler, S., Gueran, T., Abali, S., Biebermann, H., Bereket, A., Grueters, A., Chen, W. and Krude, H.
Journal of Clinical Endocrinology and Metabolism 99
(1): E169-E176.
January 2014
Noradrenergic blockade and memory in patients with major depression and healthy participants.
Kuffel, A., Eikelmann, S., Terfehr, K., Mau, G., Kuehl, L.K., Otte, C., Loewe, B., Spitzer, C. and Wingenfeld, K.
Psychoneuroendocrinology 40
: 86-90.
February 2014
STITCH 4: integration of protein-chemical interactions with user data.
Kuhn, M., Szklarczyk, D., Pletscher-Frankild, S., Blicher, T.H., von Mering, C., Jensen, L.J. and Bork, P.
Nucleic Acids Research 42
(1): D401-D407.
1 January 2014
Sequence Bundles: a novel method for visualising, discovering and exploring sequence motifs.
Kultys, M., Nicholas, L., Schwarz, R., Goldman, N. and King, J.
BMC Proceedings 8
(Suppl 2): S8.
28 August 2014
Impact of structural differences in hyperbranched polyglycerol–polyethylene glycol nanoparticles on dermal drug delivery and biocompatibility.
Kumar, S., Alnasif, N., Fleige, E., Kurniasih, I., Kral, V., Haase, A., Luch, A., Weindl, G., Haag, R., Schäfer-Korting, M. and Hedtrich, S.
European Journal of Pharmaceutics and Biopharmaceutics 88
(3): 625-34.
November 2014
Alteration of protein levels during influenza virus H1N1 infection in host cells: a proteomic survey of host and virus reveals differential dynamics.
Kummer, S., Flöttmann, M., Schwanhäusser, B., Sieben, C., Veit, M., Selbach, M., Klipp, E. and Herrmann, A.
PLoS ONE 9
(4): e94257.
9 April 2014
A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium.
Kuppusamy, M., Caroccia, B., Stindl, J., Bandulik, S., Lenzini, L., Gioco, F., Fishman, V., Zanotti, G., Gomez-Sanchez, C., Bader, M., Warth, R. and Rossi, G.P.
Journal of Clinical Endocrinology and Metabolism 99
(9): E1765-E1773.
September 2014
LRP2 mediates folate uptake in the developing neural tube.
Kur, E., Mecklenburg, N., Cabrera, R.M., Willnow, T.E. and Hammes, A.
Journal of Cell Science 127
(Pt 10): 2261-2268.
15 May 2014
PR interval identifies clinical response in patients with non-left bundle branch block : a multicenter automatic defibrillator implantation Trial-cardiac resynchronization therapy substudy.
Kutyifa, V., Stockburger, M., Daubert, J.P., Holmqvist, F., Olshansky, B., Schuger, C., Klein, H., Goldenberg, I., Brenyo, A., McNitt, S., Merkely, B., Zareba, W. and Moss, A.J.
Circulation Arrhythmia and Electrophysiology 7
(4): 645-651.
August 2014
Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study.
Kvehaugen, A.S., Melien, Ø., Holmen, O.L., Laivuori, H., Dechend, R. and Staff, A.C.
BMC Medical Genetics 15
: 28.
5 March 2014
Plasma alkylresorcinols, biomarkers of whole-grain wheat and rye intake, and incidence of colorectal cancer.
Kyrø, C, Olsen, A, Landberg, R, Skeie, G, Loft, S, Åman, P, Leenders, M, Dik, VK, Siersema, PD, Pischon, T., Christensen, J, Overvad, K, Boutron-Ruault, MC, Fagherazzi, G, Cottet, V, Kühn, T, Chang-Claude, J, Boeing, H, Trichopoulou, A, Bamia, C, Trichopoulos, D, Palli, D, Krogh, V, Tumino, R, Vineis, P, Panico, S, Peeters, PH, Weiderpass, E, Bakken, T, Åsli, LA, Argüelles, M, Jakszyn, P, Sánchez, MJ, Amiano, P, Huerta, JM, Barricarte, A, Ljuslinder, I, Palmqvist, R, Khaw, KT, Wareham, N, Key, TJ, Travis, RC, Ferrari, P, Freisling, H, Jenab, M, Gunter, MJ, Murphy, N, Riboli, E, Tjønneland, A and Bueno-de-Mesquita, HB
Journal of the National Cancer Institute 106
(1): djt352.
1 January 2014
Plasma alkylresorcinol concentrations, biomarkers of whole-grain wheat and rye intake, in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
Kyrø, C., Olsen, A., Bueno-de-Mesquita, H.B., Skeie, G., Loft, S., Åman, P., Leenders, M., Dik, V.K., Siersema, P.D., Pischon, T., Christensen, J., Overvad, K., Boutron-Ruault, M.C., Fagherazzi, G., Cottet, V., Kühn, T., Chang-Claude, J., Boeing, H., Trichopoulou, A., Naska, A., Oikonomidou, D., Masala, G., Pala, V., Tumino, R., Vineis, P., Mattiello, A., Peeters, P.H., Bakken, T., Weiderpass, E., Asli, L.A., Sánchez, S., Jakszyn, P., Sánchez, M.J., Amiano, P., Huerta, J.M., Barricarte, A., Ljuslinder, I., Palmqvist, R., Khaw, K.T., Wareham, N., Key, T.J., Travis, R.C., Slimani, N., Freisling, H., Ferrari, P., Gunter, M.J., Murphy, N., Riboli, E., Tjønneland, A. and Landberg, R.
British Journal of Nutrition 111
(10): 1881-1890.
May 2014
Evidence-based patient information programme in early multiple sclerosis: a randomised controlled trial.
Köpke, S., Kern, S., Ziemssen, T., Berghoff, M., Kleiter, I., Marziniak, M., Paul, F., Vettorazzi, E., Pöttgen, J., Fischer, K., Kasper, J. and Heesen, C.
Journal of Neurology Neurosurgery and Psychiatry 85
(4): 411-418.
April 2014
Genome-wide genotyping of acute myeloid leukemia with translocation t(9;11)(p22;q23) reveals novel recurrent genomic alterations.
Kühn, M.W.M., Bullinger, L., Gröschel, S., Krönke, J., Edelmann, J., Rücker, F.G., Eiwen, K., Paschka, P., Gaidzik, V.I., Holzmann, K., Schlenk, R.F., Döhner, H. and Döhner, K.
Haematologica 99
(8): 133-135.
August 2014
e-RNA: a collection of web servers for comparative RNA structure prediction and visualisation.
Lai, D. and Meyer, I.M.
Nucleic Acids Research 42
(Web Server issue): W373-W376.
1 July 2014
DEPDC5 mutations in genetic focal epilepsies of childhood.
Lal, D., Reinthaler, E.M., Schubert, J., Muhle, H., Riesch, E., Kluger, G., Jabbari, K., Kawalia, A., Bäumel, C., Holthausen, H., Hahn, A., Feucht, M., Neophytou, B., Haberlandt, E., Becker, F., Altmüller, J., Thiele, H., Lemke, J.R., Lerche, H., Nürnberg, P., Sander, T., Weber, Y., Zimprich, F. and Neubauer, B.A.
Annals of Neurology 75
(5): 788-792.
May 2014
Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells.
Lancini, C., van den Berk, P.C.M., Vissers, J.H.A., Gargiulo, G., Song, J.Y., Hulsman, D., Serresi, M., Tanger, E., Blom, M., Vens, C., van Lohuizen, M., Jacobs, H. and Citterio, E.
Journal of Experimental Medicine 211
(9): 1759-1777.
25 August 2014
Dynamics of a semiflexible polymer or polymer ring in shear flow.
Lang, P.S., Obermayer, B. and Frey, E.
Physical Review E 89
(2): 022606.
27 February 2014
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Langenfurth, A., Rinnenthal, J.L., Vinnakota, K., Prinz, V., Carlo, A.S., Stadelmann, C., Siffrin, V., Peaschke, S., Endres, M., Heppner, F., Glass, R., Wolf, S.A. and Kettenmann, H.
Journal of Neuroscience Research 92
(3): 275-286.
March 2014
Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy.
Langhans, C., Weber-Carstens, S., Schmidt, F., Hamati, J., Kny, M., Zhu, X., Wollersheim, T., Koch, S., Krebs, M., Schulz, H., Lodka, D., Saar, K., Labeit, S., Spies, C., Hubner, N., Spranger, J., Spuler, S., Boschmann, M., Dittmar, G., Butler-Browne, G., Mouly, V. and Fielitz, J.
PLoS ONE 9
(3): e92048.
20 March 2014
Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin.
Lectez, B., Migotti, R., Lee, S.Y., Ramirez, J., Beraza, N., Mansfield, B., Sutherland, J., Martinez-Chantar, M.L., Dittmar, G. and Mayor, U.
Journal of Proteome Research 13
(6): 3016-3026.
6 June 2014
Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5.
Lee, G.S., Simpson, C., Sun, B.H., Yao, C., Foer, D., Sullivan, B., Matthes, S., Alenina, N., Belsky, J., Bader, M. and Insogna, K.L.
Journal of Bone and Mineral Research 29
(4): 976-981.
April 2014
Increase of angiotensin II type 1 receptor auto-antibodies in Huntington's disease.
Lee, D.H., Heidecke, H., Schröder, A., Paul, F., Wachter, R., Hoffmann, R., Ellrichmann, G., Dragun, D., Waschbisch, A., Stegbauer, J., Klotz, P., Gold, R., Dechend, R., Müller, D.N., Saft, C. and Linker, R.A.
Molecular Neurodegeneration 9
(1): 49.
15 November 2014
Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis.
Lee, J., Kim, Y., Yi, H., Diecke, S., Kim, J., Jung, H., Rim, Y.A., Jung, S.M., Kim, M., Kim, Y.G., Park, S.H., Kim, H.Y. and Ju, J.H.
Arthritis Research & Therapy 16
(1): R41.
4 February 2014
Functionally aberrant electrophysiological cortical connectivities in first episode medication-naive schizophrenics from three psychiatry centers.
Lehmann, D., Faber, P.L., Pascual-Marqui, R.D., Milz, P., Herrmann, W.M., Koukkou, M., Saito, N., Winterer, G. and Kochi, K.
Frontiers in Human Neuroscience 8
: 635.
20 August 2014
Targeting high-grade B cell lymphoma with CD19-specific T cells.
Lehmann, F.M., Maurberger, A., Feicht, S., Helm, F., Ladinig, C., Kieback, E., Uckert, W., Kammertöns, T., Kremmer, E., Mautner, J., Gerbitz, A. and Bornkamm, G.W.
International Journal of Cancer 135
(5): 1153-1164.
1 September 2014
mVOC: a database of microbial volatiles.
Lemfack, M.C., Nickel, J., Dunkel, M., Preissner, R. and Piechulla, B.
Nucleic Acids Research 42
(1): D744-D748.
1 January 2014
Lower expression of the Twik-related acid-sensitive K(+) channel 2 (TASK-2) gene is a hallmark of aldosterone producing adenoma causing human primary aldosteronism.
Lenzini, L., Caroccia, B., Campos, A.G., Fassina, A., Belloni, A.S., Seccia, T.M., Kuppusamy, M., Ferraro, S., Skander, G., Bader, M., Rainey, W.E. and Rossi, G.P.
Journal of Clinical Endocrinology and Metabolism 99
(4): E674-E682.
April 2014
Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features.
Lessel, D., Vaz, B., Halder, S., Lockhart, P.J., Marinovic-Terzic, I., Lopez-Mosqueda, J., Philipp, M., Sim, J.C.H., Smith, K.R., Oehler, J., Cabrera, E., Freire, R., Pope, K., Nahid, A., Norris, F., Leventer, R.J., Delatycki, M., Barbi, G., von Ameln, S., Högel, J., Degoricija, M., Fertig, R., Burkhalter, M.D., Hofmann, K., Thiele, H., Altmüller, J., Nürnberg, G., Nürnberg, P., Bahlo, M., Martin, G.M., Aalfs, C.M., Oshima, J., Terzic, J., Amor, D.J., Dikic, I., Ramadan, K. and Kubisch, C.
Nature Genetics 46
(11): 1239-1244.
November 2014
Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase.
Leuenberger, T., Pfueller, C.F., Luessi, F., Bendix, I., Paterka, M., Prozorovski, T., Treue, D., Luenstedt, S., Herz, J., Siffrin, V., Infante-Duarte, C., Zipp, F. and Waiczies, S.
PLoS ONE 9
(7): e100871.
11 July 2014
Nerve growth factor and nociception: from experimental embryology to new analgesic therapy.
Lewin, G.R., Lechner, S.G. and Smith, E.S.J.
Handbook of Experimental Pharmacology 220
: 251-282.
2014
Preface.
Lewin, G.R. and Carter, B.D.
Handbook of Experimental Pharmacology 220
: v-vi.
2014
An integrated catalog of reference genes in the human gut microbiome.
Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J.R., Prifti, E., Nielsen, T., Juncker, A.S., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D., Zhang, Z., Chen, W., Zhao, H., Al-Aama, J.Y., Edris, S., Yang, H., Wang, J., Hansen, T., Nielsen, H.B., Brunak, S., Kristiansen, K., Guarner, F., Pedersen, O., Dore, J., Ehrlich, S.D., Bork, P. and Wang, J.
Nature Biotechnology 32
(8): 834-841.
August 2014
Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study.
Libri, V., Yandim, C., Athanasopoulos, S., Loyse, N., Natisvili, T., Law, P.P., Chan, P.K., Mohammad, T., Mauri, M., Tam, K.T., Leiper, J., Piper, S., Ramesh, A., Parkinson, M.H., Huson, L., Giunti, P. and Festenstein, R.
Lancet 384
(9942): 504-513.
9 August 2014
Unbiased expression mapping identifies a link between the complement and cholinergic systems in the rat central nervous system.
Lindblom, R.P.F., Ström, M., Heinig, M., Al Nimer, F., Aeinehband, S., Berg, A., Dominguez, C.A., Vijayaraghavan, S., Zhang, X.M., Harnesk, K., Zelano, J., Hübner, N., Cullheim, S., Darreh-Shori, T., Diez, M. and Piehl, F.
Journal of Immunology 192
(3): 1138-1153.
1 February 2014
High spatial resolution in vivo magnetic resonance imaging of the human eye, orbit, nervus opticus and optic nerve sheath at 7.0 Tesla.
Lindner, T., Langner, S., Graessl, A., Rieger, J., Schwerter, M., Muhle, M., Lysiak, D., Kraus, O., Wuerfel, J., Guthoff, R.F., Falke, K., Hadlich, S., Krueger, P.C., Hosten, N., Niendorf, T. and Stachs, O.
Experimental Eye Research 125
: 89-94.
August 2014
ALK pERKs up MYCN in neuroblastoma.
Lindner, S., Henssen, A., Astrahantseff, K. and Schulte, J.H.
Science Signaling 7
(349): pe27.
28 October 2014
Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing.
Lipka, D.B., Wang, Q., Cabezas-Wallscheid, N., Klimmeck, D., Weichenhan, D., Herrmann, C., Lier, A., Brocks, D., von Paleske, L., Renders, S., Wünsche, P., Zeisberger, P., Gu, L., Haas, S., Essers, M.A., Brors, B., Eils, R., Trumpp, A., Milsom, M.D. and Plass, C.
Cell Cycle 13
(22): 3476-3487.
10 December 2014
Greater power and computational efficiency for kernel-based association testing of sets of genetic variants.
Lippert, C., Xiang, J., Horta, D., Widmer, C., Kadie, C., Heckerman, D. and Listgarten, J.
Bioinformatics 30
(22): 3206-3214.
15 November 2014
Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action.
Loos, M., Mueller, T., Gouwenberg, Y., Wijnands, R., van der Loo, R.J., Birchmeier, C., Smit, A.B. and Spijker, S.
Biological Psychiatry 76
(8): 648-655.
15 October 2014
The activity of catechol-O-methyltransferase (COMT) is not impaired by high doses of epigallocatechin-3-gallate (EGCG) in vivo.
Lorenz, M., Paul, F., Moobed, M., Baumann, G., Zimmermann, B.F., Stangl, K. and Stangl, V.
European Journal of Pharmacology 740
: 645-651.
5 October 2014
4D flow magnetic resonance imaging in bicuspid aortic valve disease demonstrates altered distribution of aortic blood flow helicity.
Lorenz, R., Bock, J., Barker, A.J., von Knobelsdorff-Brenkenhoff, F., Wallis, W., Korvink, J.G., Bissell, M.M., Schulz-Menger, J. and Markl, M.
Magnetic Resonance in Medicine 71
(4): 1542-1553.
April 2014
Molecular mechanism regulating myosin and cardiac functions by ELC.
Lossie, J., Köhncke, C., Mahmoodzadeh, S., Steffen, W., Canepari, M., Maffei, M., Taube, M., Larchevêque, O., Baumert, P., Haase, H., Bottinelli, R., Regitz-Zagrosek, V. and Morano, I.
Biochemical and Biophysical Research Communications 450
(1): 464-469.
18 July 2014
Dual proteolytic pathways govern glycolysis and immune competence.
Lu, W., Zhang, Y., McDonald, D.O., Jing, H., Carroll, B., Robertson, N., Zhang, Q., Griffin, H., Sanderson, S., Lakey, J.H., Morgan, N.V., Reynard, L.N., Zheng, L., Murdock, H.M., Turvey, S.E., Hackett, S.J., Prestidge, T., Hall, J.M., Cant, A.J., Matthews, H.F., Koref, M.F.S., Simon, A.K., Korolchuk, V.I., Lenardo, M.J., Hambleton, S. and Su, H.C.
Cell 159
(7): 1578-1590.
18 December 2014
Aberrant DNA methylation in ES cells.
Ludwig, G., Nejman, D., Hecht, M., Orlanski, S., Abu-Remaileh, M., Yanuka, O., Sandler, O., Marx, A., Roberts, D., Benvenisty, N., Bergman, Y., Mendelsohn, M. and Cedar, H.
PLoS ONE 9
(5): e96090.
22 May 2014
Altered translation of GATA1 in Diamond-Blackfan anemia.
Ludwig, L.S., Gazda, H.T., Eng, J.C., Eichhorn, S.W., Thiru, P., Ghazvinian, R., George, T.I., Gotlib, J.R., Beggs, A.H., Sieff, C.A., Lodish, H.F., Lander, E.S. and Sankaran, V.G.
Nature Medicine 20
(7): 748-753.
July 2014
Perspective on combination RAS blocking therapy: Off-TARGET, Dis-CORD, MAP-to-Nowhere, Low ALTITUDE, and NEPHRON-D.
Luft, F.C.
American Journal of Nephrology 39
(1): 46-49.
15 January 2014
Transcriptomics assisted proteomic analysis of Nicotiana occidentalis infected by Candidatus Phytoplasma mali strain AT.
Luge, T., Kube, M., Freiwald, A., Meierhofer, D., Seemüller, E. and Sauer, S.
Proteomics 14
(16): 1882-1889.
August 2014
Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space.
Ma, X., Pietsch, J., Wehland, M., Schulz, H., Saar, K., Hübner, N., Bauer, J., Braun, M., Schwarzwälder, A., Segerer, J., Birlem, M., Horn, A., Hemmersbach, R., Wasser, K., Grosse, J., Infanger, M. and Grimm, D.
FASEB Journal 28
(2): 813-835.
February 2014
Binding site discovery from nucleic acid sequences by discriminative learning of hidden Markov models.
Maaskola, J. and Rajewsky, N.
Nucleic Acids Research 42
(21): 12995-13011.
1 December 2014
Lange nichtkodierende RNA (lncRNA) : Gen- und Genomregulation [Long non-coding RNA (lncRNA) : gene and genome regulation].
Maass, P.G.
Medizinische Genetik 26
(1): 5-10.
March 2014
RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.
Maatz, H., Jens, M., Liss, M., Schafer, S., Heinig, M., Kirchner, M., Adami, E., Rintisch, C., Dauksaite, V., Radke, M.H., Selbach, M., Barton, P.J.R., Cook, S.A., Rajewsky, N., Gotthardt, M., Landthaler, M. and Hubner, N.
Journal of Clinical Investigation 124
(8): 3419-3430.
1 August 2014
Generation of neuronal progenitor cells in response to tumors in the human brain.
Macas, J., Ku, M.C., Nern, C., Xu, Y., Bühler, H., Remke, M., Synowitz, M., Franz, K., Seifert, V., Plate, K.H., Kettenmann, H., Glass, R. and Momma, S.
Stem Cells 32
(1): 244-257.
January 2014
Efficient application of next-generation sequencing for the diagnosis of rare genetic syndromes.
Madrigal, I., Alvarez-Mora, M.I., Karlberg, O., Rodríguez-Revenga, L., Elurbe, D.M., Rabionet, R., Mur, A., Pie, J., Ballesta, F., Sauer, S., Syvänen, A.C. and Milà, M.
Journal of Clinical Pathology 67
(12): 1099-1103.
December 2014
Tumor vessel normalization by chloroquine independent of autophagy.
Maes, H., Kuchnio, A., Peric, A., Moens, S., Nys, K., De Bock, K., Quaegebeur, A., Schoors, S., Georgiadou, M., Wouters, J., Vinckier, S., Vankelecom, H., Garmyn, M., Vion, A.C., Radtke, F., Boulanger, C., Gerhardt, H., Dejana, E., Dewerchin, M., Ghesquière, B., Annaert, W., Agostinis, P. and Carmeliet, P.
Cancer Cell 26
(2): 190-206.
11 August 2014
Bradykinin in health and disease: proceedings of the Bradykinin Symposium 2012, Berlin 23-24 August 2012.
Magerl, M., Bader, M., Gompel, A., Joseph, K., Kaplan, A.P., Kojda, G., Renné, T., Wirth, M., Maurer, M. and Church, M.K.
Inflammation Research 63
(3): 173-8.
March 2014
Cardiomyocyte-specific estrogen receptor alpha increases angiogenesis, lymphangiogenesis and reduces fibrosis in the female mouse heart post-myocardial infarction.
Mahmoodzadeh, S., Leber, J., Zhang, X., Jaisser, F., Messaoudi, S., Morano, I., Furth, P.A., Dworatzek, E. and Regitz-Zagrosek, V.
Journal of Cell Science & Therapy 5
(1): 153.
30 January 2014
Improved transcript isoform discovery using ORF graphs.
Majoros, W.H., Lebeck, N., Ohler, U. and Li, S.
Bioinformatics 30
(14): 1958-1964.
15 July 2014
The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells.
Malhotra, G.K., Zhao, X., Edwards, E., Kopp, J.L., Naramura, M., Sander, M., Band, H. and Band, V.
BMC Developmental Biology 14
: 47.
20 December 2014
Web-based questionnaires to capture acute infections in long-term cohorts : findings of a feasibility study.
Mall, S., Akmatov, M.K., Schultze, A., Ahrens, W., Obi, N., Pessler, F. and Krause, G.
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 57
(11): 1308-1314.
November 2014
Angiotensin IV is induced in experimental autoimmune encephalomyelitis but fails to influence the disease.
Manzel, A., Domenig, O., Ambrosius, B., Kovacs, A., Stegbauer, J., Poglitsch, M., Mueller, D.N., Gold, R. and Linker, R.A.
Journal of Neuroimmune Pharmacology 9
(4): 533-543.
September 2014
Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia.
Mar, B.G., Bullinger, L.B., McLean, K.M., Grauman, P.V., Harris, M.H., Stevenson, K., Neuberg, D.S., Sinha, A.U., Sallan, S.E., Silverman, L.B., Kung, A.L., Lo Nigro, L., Ebert, B.L. and Armstrong, S.A.
Nature Communications 5
: 3469.
24 March 2014
Human satellite cells have regenerative capacity and are genetically manipulable.
Marg, A., Escobar, H., Gloy, S., Kufeld, M., Zacher, J., Spuler, A., Birchmeier, C., Izsvák, Z. and Spuler, S.
Journal of Clinical Investigation 124
(10): 4257-4265.
1 October 2014
Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.
Markó, L., Henke, N., Park, J.K., Spallek, B., Qadri, F., Balogh, A., Apel, I.J., Oravecz-Wilson, K.I., Choi, M., Przybyl, L., Binger, K.J., Haase, N., Wilck, N., Heuser, A., Fokuhl, V., Ruland, J., Lucas, P.C., McAllister-Lucas, L.M., Luft, F.C., Dechend, R. and Müller, D.N.
Hypertension 64
(5): 1032-1039.
November 2014
Coxsackie and adenovirus receptor (CAR) is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia.
Marsman, R.F.J., Bezzina, C.R., Freiberg, F., Verkerk, A.O., Adriaens, M.E., Podliesna, S., Chen, C., Purfürst, B., Spallek, B., Koopmann, T.T., Baczko, I., Dos Remedios, C.G., George, A.L., Bishopric, N.H., Lodder, E.M., de Bakker, J.M.T., Fischer, R., Coronel, R., Wilde, A.A.M., Gotthardt, M. and Remme, C.A.
Journal of the American College of Cardiology 63
(6): 549-559.
18 February 2014
Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy.
Martin, C.A., Ahmad, I., Klingseisen, A., Hussain, M.S., Bicknell, L.S., Leitch, A., Nürnberg, G., Toliat, M.R., Murray, J.E., Hunt, D., Khan, F., Ali, Z., Tinschert, S., Ding, J., Keith, C., Harley, M.E., Heyn, P., Müller, R., Hoffmann, I., Cormier-Daire, V., Dollfus, H., Dupuis, L., Bashamboo, A., McElreavey, K., Kariminejad, A., Mendoza-Londono, R., Moore, A.T., Saggar, A., Schlechter, C., Weleber, R., Thiele, H., Altmüller, J., Höhne, W., Hurles, M.E., Noegel, A.A., Baig, S.M., Nürnberg, P. and Jackson, A.P.
Nature Genetics 46
(12): 1283-1292.
December 2014
Proteomic and functional consequences of hexokinase deficiency in glucose-repressible Kluyveromyces lactis.
Mates, N., Kettner, K., Heidenreich, F., Pursche, T., Migotti, R., Kahlert, G., Kuhlisch, E., Breunig, K.D., Schellenberger, W., Dittmar, G., Hoflack, B. and Kriegel, T.M.
Molecular & Cellular Proteomics 13
(3): 860-875.
1 March 2014
Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia.
Mattei, D., Djodari-Irani, A., Hadar, R., Pelz, A., de Cossio, L.F., Goetz, T., Matyash, M., Kettenmann, H., Winter, C. and Wolf, S.A.
Brain Behavior and Immunity 38
: 175-184.
May 2014
Swelling and mechanical properties of alginate hydrogels with respect to promotion of neural growth.
Matyash, M., Despang, F., Ikonomidou, C. and Gelinsky, M.
Tissue Engineering Part C Methods 20
(5): 401-411.
May 2014
Pathophysiology of the cardiorenal syndromes: executive summary from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI).
McCullough, P.A., Kellum, J.A., Haase, M., Mueller, C., Damman, K., Murray, P.T., Cruz, D., House, A.A., Schmidt-Ott, K.M., Vescovo, G., Bagshaw, S.M., Hoste, E.A., Briguori, C., Braam, B., Chawla, L.S., Costanzo, M.R., Tumlin, J.A., Herzog, C.A., Mehta, R.L., Rabb, H., Shaw, A.D., Singbartl, K. and Ronco, C.
Blood Purification 37
(Suppl 2): 2-13.
31 July 2014
Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation.
Mecklenburg, N., Martinez-Lopez, J.E., Moreno-Bravo, J.A., Perez-Balaguer, A., Puelles, E. and Martinez, S.
Glia 62
(10): 1713-1723.
October 2014
A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.
Meder, B., Rühle, F., Weis, T., Homuth, G., Keller, A., Franke, J., Peil, B., Bermejo, J.L., Frese, K., Huge, A., Witten, A., Vogel, B., Haas, J., Völker, U., Ernst, F., Teumer, A., Ehlermann, P., Zugck, C., Friedrichs, F., Kroemer, H., Dörr, M., Hoffmann, W., Maisch, B., Pankuweit, S., Ruppert, V., Scheffold, T., Kühl, U., Schultheiss, H.P., Kreutz, R., Ertl, G., Angermann, C., Charron, P., Villard, E., Gary, F., Isnard, R., Komajda, M., Lutz, M., Meitinger, T., Sinner, M.F., Wichmann, H.E., Krawczak, M., Ivandic, B., Weichenhan, D., Gelbrich, G., El-Mokhtari, N.E., Schreiber, S., Felix, S.B., Hasenfuß, G., Pfeufer, A., Hübner, N., Kääb, S., Arbustini, E., Rottbauer, W., Frey, N., Stoll, M. and Katus, H.A.
European Heart Journal 35
(16): 1069-1077.
21 April 2014
Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane.
Mehnert, M., Sommer, T. and Jarosch, E.
Nature Cell Biology 16
(1): 77-86.
January 2014
FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum.
Meier, F., Giesert, F., Delic, S., Faus-Kessler, T., Matheus, F., Simeone, A., Hoelter, S.M., Kühn, R., Vogt-Weisenhorn, D.M., Wurst, W. and Prakash, N.
PLoS ONE 9
(7): e101124.
1 July 2014
Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs.
Meierhofer, D., Weidner, C. and Sauer, S.
Journal of Proteome Research 13
(12): 5592-5602.
5 December 2014
Detailing magnetic field strength dependence and segmental artifact distribution of myocardial effective transverse relaxation rate at 1.5, 3.0, and 7.0 T.
Meloni, A., Hezel, F., Positano, V., Keilberg, P., Pepe, A., Lombardi, M. and Niendorf, T.
Magnetic Resonance in Medicine 71
(6): 2224-2230.
June 2014
Bone marrow T-cell infiltration during acute GVHD is associated with delayed B-cell recovery and function after HSCT.
Mensen, A., Jöhrens, K., Anagnostopoulos, I., Demski, S., Oey, M., Stroux, A., Hemmati, P., Westermann, J., Blau, O., Wittenbecher, F., Movassaghi, K., Szyska, M., Thomas, S., Dörken, B., Scheibenbogen, C., Arnold, R. and Na, I.K.
Blood 124
(6): 963-972.
7 August 2014
Comparison of different rabbit ATG preparation effects on early lymphocyte subset recovery after allogeneic HSCT and its association with EBV-mediated PTLD.
Mensen, A., Na, I.K., Häfer, R., Meerbach, A., Schlecht, M., Pietschmann, M.L. and Gruhn, B.
Journal of Cancer Research and Clinical Oncology 140
(11): 1971-1980.
November 2014
Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.
Mertins, P., Yang, F., Liu, T., Mani, D.R., Petyuk, V.A., Gillette, M.A., Clauser, K.R., Qiao, J.W., Gritsenko, M.A., Moore, R.J., Levine, D.A., Townsend, R., Erdmann-Gilmore, P., Snider, J.E., Davies, S.R., Ruggles, K.V., Fenyo, D., Kitchens, R.T., Li, S., Olvera, N., Dao, F., Rodriguez, H., Chan, D.W., Liebler, D., White, F., Rodland, K.D., Mills, G.B., Smith, R.D., Paulovich, A.G., Ellis, M. and Carr, S.A.
Molecular & Cellular Proteomics 13
(7): 1690-1704.
1 July 2014
NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly.
Metodiev, M.D., Spåhr, H., Loguercio Polosa, P., Meharg, C., Becker, C., Altmueller, J., Habermann, B., Larsson, N.G. and Ruzzenente, B.
PLoS Genetics 10
(2): e1004110.
February 2014
Statistics of extreme waves in random media.
Metzger, J.J., Fleischmann, R. and Geisel, T.
Physical Review Letters 112
(20): 203903.
23 May 2014
Transformation and additional malignancies are leading risk factors for an adverse course of disease in marginal zone lymphoma.
Meyer, A.H., Stroux, A., Lerch, K., Eucker, J., Eitle, J., Hohloch, K., Andrzejak, M., Possinger, K., Dörken, B., Pezzutto, A. and Scholz, C.W.
Annals of Oncology 25
(1): 210-215.
January 2014
Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth.
Michalik, K.M., You, X., Manavski, Y., Doddaballapur, A., Zoernig, M., Braun, T., John, D., Ponomareva, Y., Chen, W., Uchida, S., Boon, R.A. and Dimmeler, S.
Circulation Research 114
(9): 1389-1397.
25 April 2014
A somatosensory circuit for cooling perception in mice.
Milenkovic, N., Zhao, W.J., Walcher, J., Albert, T., Siemens, J., Lewin, G.R. and Poulet, J.F.A.
Nature Neuroscience 17
(11): 1560-1566.
November 2014
Using in vivo-biotinylated ubiquitin to describe a mitotic exit ubiquitome from human cells.
Min, M., Mayor, U., Dittmar, G. and Lindon, C.
Molecular & Cellular Proteomics 13
(9): 2411-2425.
September 2014
Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: Immune targets in demyelinating neuropathies?
Miyaji, K., Paul, F., Shahrizaila, N., Umapathi, T. and Yuki, N.
Journal of Neuroimmunology 276
(1-2): 172-174.
November 2014
Lack of CCM1 induces hypersprouting and impairs response to flow.
Mleynek, T.M., Chan, A.C., Redd, M., Gibson, C.C., Davis, C.T., Shi, D.S., Chen, T., Carter, K.L., Ling, J., Blanco, R., Gerhardt, H., Whitehead, K. and Li, D.Y.
Human Molecular Genetics 23
(23): 6223-6234.
1 December 2014
AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.
Mojallal, M., Zheng, Y., Hultin, S., Audebert, S., van Harn, T., Johnsson, P., Lenander, C., Fritz, N., Mieth, C., Corcoran, M., Lembo, F., Hallstroem, M., Hartman, J., Mazure, N.M., Weide, T., Grander, D., Borg, J.P., Uhlen, P. and Holmgren, L.
Nature Communications 5
: 4557.
1 August 2014
Progressive replacement of embryo-derived cardiac macrophages with age.
Molawi, K., Wolf, Y., Kandalla, P.K., Favret, J., Hagemeyer, N., Frenzel, K., Pinto, A.R., Klapproth, K., Henri, S., Malissen, B., Rodewald, H.R., Rosenthal, N.A., Bajenoff, M., Prinz, M., Jung, S. and Sieweke, M.H.
Journal of Experimental Medicine 211
(11): 2151-2158.
20 October 2014
Human somatic cell mutagenesis creates genetically tractable sarcomas.
Molyneux, S.D., Waterhouse, P.D., Shelton, D., Shao, Y.W., Watling, C.M., Tang, Q.L., Harris, I.S., Dickson, B.C., Tharmapalan, P., Sandve, G.K., Zhang, X., Bailey, S.D., Berman, H., Wunder, J.S., Izsvák, Z., Lupien, M., Mak, T.W. and Khokha, R.
Nature Genetics 46
(9): 964-972.
September 2014
Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease.
Morgen, K., Ramirez, A., Froelich, L., Tost, H., Plichta, M.M., Koelsch, H., Rakebrandt, F., Rienhoff, O., Jessen, F., Peters, O., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Hampel, H., Teipel, S.J., Pantel, J., Heuser, I., Wiltfang, J., Ruether, E., Kornhuber, J., Maier, W. and Meyer-Lindenberg, A.
Alzheimer's & Dementia 10
(5 Suppl): S269-S276.
October 2014
Paired-end analysis of transcription start sites in Arabidopsis reveals plant-specific promoter signatures.
Morton, T., Petricka, J., Corcoran, D.L., Li, S., Winter, C.M., Carda, A., Benfey, P.N., Ohler, U. and Megraw, M.
Plant Cell 26
(7): 2746-2760.
July 2014
Adaptive changes in serotonin metabolism preserve normal behavior in mice with reduced TPH2 activity.
Mosienko, V., Matthes, S., Hirth, N., Beis, D., Flinders, M., Bader, M., Hansson, A.C. and Alenina, N.
Neuropharmacology 85C
: 73-80.
October 2014
WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors.
Motamedi, F.J., Badro, D.A., Clarkson, M., Rita Lecca, M., Bradford, S.T., Buske, F.A., Saar, K., Hübner, N., Bräendli, A.W. and Schedl, A.
Nature Communications 5
: 4444.
17 July 2014
Vessel labeling in combined confocal scanning laser ophthalmoscopy and optical coherence tomography Images : criteria for blood vessel discrimination.
Motte, J., Alten, F., Ewering, C., Osada, N., Kadas, E.M., Brandt, A.U., Oberwahrenbrock, T., Clemens, C.R., Eter, N., Paul, F. and Marziniak, M.
PLoS ONE 9
(9): e102034.
9 September 2014
Global target mRNA specification and regulation by the RNA-binding protein ZFP36.
Mukherjee, N., Jacobs, N.C., Hafner, M., Kennington, E.A., Nusbaum, J.D., Tuschl, T., Blackshear, P.J. and Ohler, U.
Genome Biology 15
(1): R12.
8 January 2014
High-resolution profiling of protein occupancy on polyadenylated RNA transcripts.
Munschauer, M., Schueler, M., Dieterich, C. and Landthaler, M.
Methods 65
(3): 302-309.
February 2014
COUGER-co-factors associated with uniquely-bound genomic regions.
Munteanu, A., Ohler, U. and Gordân, R.
Nucleic Acids Research 42
(Web Server issue): W461-W467.
July 2014
Increased catabolic state in spinocerebellar ataxia type 1 patients.
Mähler, A., Steiniger, J., Endres, M., Paul, F., Boschmann, M. and Doss, S.
Cerebellum 13
(4): 440-446.
August 2014
Models of chromosome structure.
Nicodemi, M. and Pombo, A.
Current Opinion in Cell Biology 28
: 90-95.
1 June 2014
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
Nielsen, H.B., Almeida, M., Juncker, A.S., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D.R., Gautier, L., Pedersen, A.G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J.M., Quintanilha Dos Santos, M.B., Blom, N., Borruel, N., Burgdorf, K.S., Boumezbeur, F., Casellas, F., Dore, J., Dworzynski, P., Guarner, F., Hansen, T., Hildebrand, F., Kaas, R.S., Kennedy, S., Kristiansen, K., Kultima, J.R., Leonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, O., Prifti, E., Qin, J., Raes, J., Sorensen, S., Tap, J., Tims, S., Ussery, D.W., Yamada, T., Renault, P., Sicheritz-Ponten, T., Bork, P., Wang, J., Brunak, S. and Ehrlich, S.D.
Nature Biotechnology 32
(8): 822-828.
August 2014
Dietary patterns during high school and risk of colorectal adenoma in a cohort of middle-aged women.
Nimptsch, K., Malik, V.S., Fung, T.T., Pischon, T., Hu, F.B., Willett, W.C., Fuchs, C.S., Ogino, S., Chan, A.T., Giovannucci, E. and Wu, K.
International Journal of Cancer 134
(10): 2458-2467.
15 May 2014
Assessment of serum protein dynamics by native SILAC flooding (SILflood).
Nolte, H., Hölper, S., Selbach, M., Braun, T. and Krüger, M.
Analytical Chemistry 86
(22): 11033-11037.
18 November 2014
ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics.
Norton, M., Ng, A.C., Baird, S., Dumoulin, A., Shutt, T., Mah, N., Andrade-Navarro, M.A., McBride, H.M. and Screaton, R.A.
Science Signaling 7
(310): ra10.
28 January 2014
Analysis of α3 GlyR single particle tracking in the cell membrane.
Notelaers, K., Rocha, S., Paesen, R., Smisdom, N., De Clercq, B., Meier, J.C., Rigo, J.M., Hofkens, J. and Ameloot, M.
Biochimica et Biophysica Acta - Molecular Cell Research 1843
(3): 544-553.
March 2014
Membrane distribution of the glycine receptor α3 studied by optical super-resolution microscopy.
Notelaers, K., Rocha, S., Paesen, R., Swinnen, N., Vangindertael, J., Meier, J.C., Rigo, J.M., Ameloot, M. and Hofkens, J.
Histochemistry and Cell Biology 142
(1): 79-90.
July 2014
Filariasis asymptomatically infected donors have lower levels of disialylated IgG compared to endemic normals.
O'Regan, N.L., Steinfelder, S., Schwedler, C., Rao, G.B., Srikantam, A., Blanchard, V. and Hartmann, S.
Parasite Immunology 36
(12): 713-720.
December 2014
Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate and adaptive immune responses.
O'Regan, N.L., Steinfelder, S., Venugopal, G., Rao, G.B., Lucius, R., Srikantam, A. and Hartmann, S.
PLoS Neglected Tropical Diseases 8
(10): e3206.
2 October 2014
Clinical lessons to be learned from patients developing chronic myeloid leukemia while on immunosuppressive therapy after solid organ transplantation: yet another dase after orthotopic heart transplantation.
Oberender, C., Kleeberg, L., Nienhues, N., Gresse, M., Doerken, B., Riess, H. and le Coutre, P.
Case Reports in Hematology 2014
: 890438.
16 November 2014
Inverse Ising inference with correlated samples.
Obermayer, B. and Levine, E.
New Journal of Physics 16
: 123017.
8 December 2014
Exploring the miRNA regulatory network using evolutionary correlations.
Obermayer, B. and Levine, E.
PLoS Computational Biology 10
(10): e1003860.
9 October 2014
Second-line oxaliplatin, folinic acid, and fluorouracil versus folinic acid and fluorouracil alone for gemcitabine-refractory pancreatic cancer : outcomes from the CONKO-003 trial.
Oettle, H., Riess, H., Stieler, J.M., Heil, G., Schwaner, I., Seraphin, J., Goerner, M., Moelle, M., Greten, T.F., Lakner, V., Bischoff, S., Sinn, M., Doerken, B. and Pelzer, U.
Journal of Clinical Oncology 32
(23): 2423-2429.
10 August 2014
Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein.
Olal, D., Dick, A., Woods, V.L., Liu, T., Li, S., Devignot, S., Weber, F., Saphire, E.O. and Daumke, O.
Nucleic Acids Research 42
(9): 6025-6037.
14 May 2014
Identification of the mitochondrial MSRB2 as a binding partner of LG72.
Otte, D.M., Raskó, T., Wang, M., Dreiseidler, M., Drews, E., Schrage, H., Wojtalla, A., Höhfeld, J., Wanker, E. and Zimmer, A.
Cellular and Molecular Neurobiology 34
(8): 1123-1130.
November 2014
Immunotherapy of B cell non-Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model.
Panjideh, H., Mueller, G., Koch, M., Wilde, F., Scheu, S., Moldenhauer, G. and Lipp, M.
International Journal of Cancer 135
(11): 2623-2632.
1 December 2014
The subpopulation of microglia sensitive to neurotransmitters/neurohormones is modulated by stimulation with LPS, interferon-γ, and IL-4.
Pannell, M., Szulzewsky, F., Matyash, V., Wolf, S.A. and Kettenmann, H.
Glia 62
(5): 667-679.
May 2014
α-intercalated cells defend the urinary system from bacterial infection.
Paragas, N., Kulkarni, R., Werth, M., Schmidt-Ott, K.M., Forster, C., Deng, R., Zhang, Q., Singer, E., Klose, A.D., Shen, T.H., Francis, K.P., Ray, S., Vijayakumar, S., Seward, S., Bovino, M.E., Xu, K., Takabe, Y., Amaral, F.E., Mohan, S., Wax, R., Corbin, K., Sanna-Cherchi, S., Mori, K., Johnson, L., Nickolas, T., D’Agati, V., Lin, C.S., Qiu, A., Al-Awqati, Q., Ratner, A.J. and Barasch, J.
Journal of Clinical Investigation 124
(7): 2963-2976.
1 July 2014
NanoCAGE analysis of the mouse olfactory epithelium identifies the expression of vomeronasal receptors and of proximal LINE elements.
Pascarella, G., Lazarevic, D., Plessy, C., Bertin, N., Akalin, A., Vlachouli, C., Simone, R., Faulkner, G.J., Zucchelli, S., Kawai, J., Daub, C.O., Hayashizaki, Y., Lenhard, B., Carninci, P. and Gustincich, S.
Frontiers in Cellular Neuroscience 8
: 41.
18 February 2014
Titin mutation in familial restrictive cardiomyopathy.
Peled, Y., Gramlich, M., Yoskovitz, G., Feinberg, M.S., Afek, A., Polak-Charcon, S., Pras, E., Sela, B.A., Konen, E., Weissbrod, O., Geiger, D., Gordon, P.M.K., Thierfelder, L., Freimark, D., Gerull, B. and Arad, M.
International Journal of Cardiology 171
(1): 24-30.
15 January 2014
Intensified chemotherapy and simultaneous treatment with heparin in outpatients with pancreatic cancer - the CONKO 004 pilot trial.
Pelzer, U., Hilbig, A., Stieler, J.M., Bahra, M., Sinn, M., Gebauer, B., Doerken, B. and Riess, H.
BMC Cancer 14
(1): 204.
19 March 2014
Angiotensin 1-7 reduces mortality and rupture of intracranial aneurysms in mice.
Pena Silva, R.A., Kung, D.K., Mitchell, I.J., Alenina, N., Bader, M., Santos, R.A.S., Faraci, F.M., Heistad, D.D. and Hasan, D.M.
Hypertension 64
(2): 362-368.
August 2014
Permissive expansion and homing of adoptively transferred T cells in tumor-bearing hosts.
Perez, C., Jukica, A., Listopad, J.J., Anders, K., Kühl, A.A., Loddenkemper, C., Blankenstein, T. and Charo, J.
International Journal of Cancer 137
(2): 359-371.
15 July 2014
Nuove strategie farmacologiche per la sindrome di Marfan: dai modelli animali all'uomo [Novel pharmacological strategies for aortic dilation in Marfan syndrome: from mouse models to human patients].
Perrino, C., Schiattarella, G.G., Bottino, R., Magliulo, F., Oliveti, M., Esposito, G. and Trimarco, B.
Giornale Italiano di Cardiologia 15
(7): 408-417.
July 2014
Cardiac side effects of chemotherapy: state of art and strategies for a correct management.
Perrino, C., Schiattarella, G.G., Magliulo, F., Ilardi, F., Carotenuto, G., Gargiulo, G., Serino, F., Ferrone, M., Scudiero, F., Carbone, A., Trimarco, B. and Esposito, G.
Current Vascular Pharmacology 12
(1): 106-116.
27 March 2014
Simple derivation of transgene-free iPS cells by a dual recombinase approach.
Pertek, A., Meier, F., Irmler, M., Beckers, J., Skylaki, S., Endele, M., Wurst, W., Prakash, N. and Kühn, R.
Molecular Biotechnology 56
(8): 697-713.
August 2014
Identification of differentially expressed long noncoding RNAs in bladder cancer.
Peter, S., Borkowska, E., Drayton, R.M., Rakhit, C.P., Noon, A.P., Chen, W. and Catto, J.W.F.
Clinical Cancer Research 20
(20): 5311-5321.
15 October 2014
Distinct interactions between actin and essential myosin light chain isoforms.
Petzhold, D., Simsek, B., Meißner, R., Mahmoodzadeh, S. and Morano, I.
Biochemical and Biophysical Research Communications 449
(3): 284-288.
4 July 2014
A randomized controlled multicenter trial on the multimodal treatment of adult attention-deficit hyperactivity disorder: enrollment and characteristics of the study sample.
Philipsen, A., Graf, E., Jans, T., Matthies, S., Borel, P., Colla, M., Gentschow, L., Langner, D., Jacob, C., Gross-Lesch, S., Sobanski, E., Alm, B., Schumacher-Stien, M., Roesler, M., Retz, W., Retz-Junginger, P., Kis, B., Abdel-Hamid, M., Heinrich, V., Huss, M., Kornmann, C., Buerger, A., van Elst, L.T. and Berger, M.
Attention Deficit and Hyperactivity Disorders 6
(1): 35-47.
March 2014
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits.
Piazza, I., Rutkowska, A., Ori, A., Walczak, M., Metz, J., Pelechano, V., Beck, M. and Haering, C.H.
Nature Structural & Molecular Biology 21
(6): 560-568.
June 2014
Decoding the dynamics of cellular metabolism and the action of 3-bromopyruvate and 2-deoxyglucose using pulsed stable isotope-resolved metabolomics.
Pietzke, M., Zasada, C., Mudrich, S. and Kempa, S.
Cancer & Metabolism 2
: 9.
30 June 2014
Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of MART-1-specific T cells.
Pinto, S., Sommermeyer, D., Michel, C., Wilde, S., Schendel, D., Uckert, W., Blankenstein, T. and Kyewski, B.
European Journal of Immunology 44
(9): 2811-2821.
September 2014
Design of a bZip transcription factor with homo/heterodimer-induced DNA-binding preference.
Pogenberg, V., Consani Textor, L., Vanhille, L., Holton, S.J., Sieweke, M.H. and Wilmanns, M.
Structure 22
(3): 466-477.
4 March 2014
Detailing the relation between renal T(2)* and renal tissue pO2 using an integrated approach of parametric magnetic resonance imaging and invasive physiological measurements.
Pohlmann, A., Arakelyan, K., Hentschel, J., Cantow, K., Flemming, B., Ladwig, M., Waiczies, S., Seeliger, E. and Niendorf, T.
Investigative Radiology 49
(8): 547-560.
August 2014
Cerebral blood volume estimation by ferumoxytol-enhanced steady-state MRI at 9.4 T reveals microvascular impact of α(1)-adrenergic receptor antibodies.
Pohlmann, A., Karczewski, P., Ku, M.C., Dieringer, B., Waiczies, H., Wisbrun, N., Kox, S., Palatnik, I., Reimann, H.M., Eichhorn, C., Waiczies, S., Hempel, P., Lemke, B., Niendorf, T. and Bimmler, M.
NMR in Biomedicine 27
(9): 1085-1093.
September 2014
Tuning piezo ion channels to detect molecular-scale movements relevant for fine touch.
Poole, K., Herget, R., Lapatsina, L., Ngo, H.D. and Lewin, G.R.
Nature Communications 5
: 3520.
24 March 2014
Bright/Arid3A acts as a barrier to somatic cell reprogramming through direct regulation of Oct4, Sox2, and Nanog.
Popowski, M., Templeton, T.D., Lee, B.K., Rhee, C., Li, H., Miner, C., Dekker, J.D., Orlanski, S., Bergman, Y., Iyer, V.R., Webb, C.F. and Tucker, H.
Stem Cell Reports 2
(1): 26-35.
14 January 2014
Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels.
Portelli, M.A., Siedlinski, M., Stewart, C.E., Postma, D.S., Nieuwenhuis, M.A., Vonk, J.M., Nurnberg, P., Altmuller, J., Moffatt, M.F., Wardlaw, A.J., Parker, S.G., Connolly, M.J., Koppelman, G.H. and Sayers, I.
FASEB Journal 28
(2): 923-934.
February 2014
eggNOG v4.0: nested orthology inference across 3686 organisms.
Powell, S., Forslund, K., Szklarczyk, D., Trachana, K., Roth, A., Huerta-Cepas, J., Gabaldon, T., Rattei, T., Creevey, C., Kuhn, M., Jensen, L.J., von Mering, C. and Bork, P.
Nucleic Acids Research 42
(1): D231-D239.
1 January 2014
Efficient Bayesian-based multiview deconvolution.
Preibisch, S., Amat, F., Stamataki, E., Sarov, M., Singer, R.H., Myers, E. and Tomancak, P.
Nature Methods 11
(6): 645-648.
June 2014
HIF1α modulates reprogramming through early glycolytic shift and up-regulation of PDK1-3 and PKM2.
Prigione, A., Rohwer, N., Hoffman, S., Mlody, B., Drews, K., Bukowiecki, R., Bluemlein, K., Wanker, E.E., Ralser, M., Cramer, T. and Adjaye, J.
Stem Cells 32
(2): 364-376.
February 2014
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia.
Przanowski, P., Dabrowski, M., Ellert-Miklaszewska, A., Kloss, M., Mieczkowski, J., Kaza, B., Ronowicz, A., Hu, F., Piotrowski, A., Kettenmann, H., Komorowski, J. and Kaminska, B.
Journal of Molecular Medicine 92
(3): 239-254.
March 2014
Autophagy is a critical regulator of memory CD8(+) T cell formation.
Puleston, D.J., Zhang, H., Powell, T.J., Lipina, E., Sims, S., Panse, I., Watson, A.S., Cerundolo, V., Townsend, A.R., Klenerman, P. and Simon, A.K.
eLife 3
: e03706.
11 November 2014
Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis.
Pulgar, V.M., Yamaleyeva, L.M., Varagic, J., McGee, C.M., Bader, M., Dechend, R., Howlett, A.C. and Brosnihan, K.B.
Hypertension 64
(3): 619-625.
September 2014
Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes.
Qu, Y., Lennartsson, A., Gaidzik, V.I., Deneberg, S., Karimi, M., Bengtzén, S., Höglund, M., Bullinger, L., Döhner, K. and Lehmann, S.
Epigenetics 9
(8): 1108-1119.
August 2014
Erdheim-Chester disease and knee pain in a dialysis patient.
Rademacher, S., Anagnostopoulos, J., Luft, F.C. and Kettritz, R.
Clinical Kidney Journal 7
(4): 402-405.
August 2014
TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction.
Ragancokova, D., Rocca, E., Oonk, A.M.M., Schulz, H., Rohde, E., Bednarsch, J., Feenstra, I., Pennings, R.J.E., Wende, H. and Garratt, A.N.
Journal of Clinical Investigation 124
(3): 1214-1227.
3 March 2014
Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma.
Rahal, R., Frick, M., Romero, R., Korn, J.M., Kridel, R., Chun Chan, F., Meissner, B., Bhang, H.E., Ruddy, D., Kauffmann, A., Farsidjani, A., Derti, A., Rakiec, D., Naylor, T., Pfister, E., Kovats, S., Kim, S., Dietze, K., Doerken, B., Steidl, C., Tzankov, A., Hummel, M., Monahan, J., Morrissey, M.P., Fritsch, C., Sellers, W.R., Cooke, V.G., Gascoyne, R.D., Lenz, G. and Stegmeier, F.
Nature Medicine 20
(1): 87-92.
January 2014
Novel ideas about salt, blood pressure, and pregnancy.
Rakova, N., Muller, D.N., Staff, A.C., Luft, F.C. and Dechend, R.
Journal of Reproductive Immunology 101-102
: 135-139.
March 2014
SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
Ramirez, A., van der Flier, W.M., Herold, C., Ramonet, D., Heilmann, S., Lewczuk, P., Popp, J., Lacour, A., Drichel, D., Louwersheimer, E., Kummer, M.P., Cruchaga, C., Hoffmann, P., Teunissen, C., Holstege, H., Kornhuber, J., Peters, O., Naj, A.C., Chouraki, V., Bellenguez, C., Gerrish, A., Heun, R., Froelich, L., Huell, M., Buscemi, L., Herms, S., Koelsch, H., Scheltens, P., Breteler, M.M., Ruether, E., Wiltfang, J., Goate, A., Jessen, F., Maier, W., Heneka, M.T., Becker, T. and Noethen, M.M.
Human Molecular Genetics 23
(24): 6644-6658.
15 December 2014
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Rampal, R., Akalin, A., Madzo, J., Vasanthakumar, A., Pronier, E., Patel, J., Li, Y., Ahn, J., Abdel-Wahab, O., Shih, A., Lu, C., Ward, P.S., Tsai, J.J., Hricik, T., Tosello, V., Tallman, J.E., Zhao, X., Daniels, D., Dai, Q., Ciminio, L., Aifantis, I., He, C., Fuks, F., Tallman, M.S., Ferrando, A., Nimer, S., Paietta, E., Thompson, C.B., Licht, J.D., Mason, C.E., Godley, L.A., Melnick, A., Figueroa, M.E. and Levine, R.L.
Cell Reports 9
(5): 1841-1855.
11 December 2014
Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
Ranade, S.S., Woo, S.H., Dubin, A.E., Moshourab, R.A., Wetzel, C., Petrus, M., Mathur, J., Bégay, V., Coste, B., Mainquist, J., Wilson, A.J., Francisco, A.G., Reddy, K., Qiu, Z., Wood, J.N., Lewin, G.R. and Patapoutian, A.
Nature 516
(7529): 121-125.
4 December 2014
PA28αβ reduces size and increases hydrophilicity of 20S immunoproteasome peptide products.
Raule, M., Cerruti, F., Benaroudj, N., Migotti, R., Kikuchi, J., Bachi, A., Navon, A., Dittmar, G. and Cascio, P.
Chemistry & Biology 21
(4): 470-480.
24 April 2014
The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells.
Redmer, T., Welte, Y., Behrens, D., Fichtner, I., Przybilla, D., Wruck, W., Yaspo, M.L., Lehrach, H., Schaefer, R. and Regenbrecht, C.R.A.
PLoS ONE 9
(5): e92596.
5 May 2014
Dendritic cell-mediated survival signals in Eμ-Myc B-cell lymphoma depend on the transcription factor C/EBPβ.
Rehm, A., Gätjen, M., Gerlach, K., Scholz, F., Mensen, A., Gloger, M., Heinig, K., Lamprecht, B., Mathas, S., Bégay, V., Leutz, A., Lipp, M., Dörken, B. and Höpken, U.E.
Nature Communications 5
: 5057.
30 September 2014
16p11.2 600 kb duplications confer risk for typical and atypical Rolandic epilepsy.
Reinthaler, E.M., Lal, D., Lebon, S., Hildebrand, M.S., Dahl, H.H.M., Regan, B.M., Feucht, M., Steinboeck, H., Neophytou, B., Ronen, G.M., Roche, L., Gruber-Sedlmayr, U., Geldner, J., Haberlandt, E., Hoffmann, P., Herms, S., Gieger, C., Waldenberger, M., Franke, A., Wittig, M., Schoch, S., Becker, A.J., Hahn, A., Maennik, K., Toliat, M.R., Winterer, G., Lerche, H., Nuernberg, P., Mefford, H., Scheffer, I.E., Berkovic, S.F., Beckmann, J.S., Sander, T., Jacquemont, S., Reymond, A., Zimprich, F. and Neubauer, B.A.
Human Molecular Genetics 23
(22): 6069-6080.
15 November 2014
Analysis of ELP4, SRPX2, and interacting genes in typical and atypical rolandic epilepsy.
Reinthaler, E.M., Lal, D., Jurkowski, W., Feucht, M., Steinböck, H., Gruber-Sedlmayr, U., Ronen, G.M., Geldner, J., Haberlandt, E., Neophytou, B., Hahn, A., Altmüller, J., Thiele, H., Toliat, M.R., Lerche, H., Nürnberg, P., Sander, T., Neubauer, B.A. and Zimprich, F.
Epilepsia 55
(8): 89-93.
August 2014
A conserved role for Snail as a potentiator of active transcription.
Rembold, M., Ciglar, L., Yáñez-Cuna, J.O., Zinzen, R.P., Girardot, C., Jain, A., Welte, M.A., Stark, A., Leptin, M. and Furlong, E.E.M.
Genes & Development 28
(2): 167-181.
15 January 2014
TCR-engineered T cells: a model of inducible TCR expression to dissect the interrelationship between two TCRs.
Reuß, S., Sebestyén, Z., Heinz, N., Loew, R., Baum, C., Debets, R. and Uckert, W.
European Journal of Immunology 44
(1): 265-274.
January 2014
A student-centered approach for developing active learning: the construction of physical models as a teaching tool in medical physiology.
Rezende-Filho, F.M., Da Fonseca, L.J.S., Nunes-Souza, V., Da Silva Guedes, G. and Rabelo, L.A.
BMC Medical Education 14
: 189.
15 September 2014
Ca(2+)-mediated mitochondrial ROS metabolism augments Wnt/β-catenin pathway activation to facilitate cell differentiation.
Rharass, T., Lemcke, H., Lantow, M., Kuznetsov, S.A., Weiss, D.G. and Panáková, D.
Journal of Biological Chemistry 289
(40): 27937-27951.
3 October 2014
Glioma-associated microglia and macrophages/monocytes display distinct electrophysiological properties and do not communicate via gap junctions.
Richter, N., Wendt, S., Georgieva, P.B., Hambardzumyan, D., Nolte, C. and Kettenmann, H.
Neuroscience Letters 583
: 130-135.
7 November 2014
A high content screening assay for evaluation of biomaterial-mediated cell fusion processes.
Rijckaert, B., Neffe, A.T., Roch, T., Gebauer, T., Pierce, B.F., Görs, J., Smink, J.J., Gossen, M., Lendlein, A. and Leutz, A.
Macromolecular Symposia 346
(1): 91-99.
December 2014
Effects of Jak2 type 1 inhibitors NVP-BSK805 and NVP-BVB808 on Jak2 mutation-positive and Bcr-Abl-positive cell lines.
Ringel, F., Kaeda, J., Schwarz, M., Oberender, C., Grille, P., Doerken, B., Marque, F., Manley, P.W., Radimerski, T. and le Coutre, P.
Acta Haematologica 132
(1): 75-86.
31 January 2014
Visual evoked potentials in neuromyelitis optica and its spectrum disorders.
Ringelstein, M., Kleiter, I., Ayzenberg, I., Borisow, N., Paul, F., Ruprecht, K., Kraemer, M., Cohn, E., Wildemann, B., Jarius, S., Hartung, H.P., Aktas, O. and Albrecht, P.
Multiple Sclerosis Journal 20
(5): 617-620.
April 2014
Contribution of spinal cord biopsy to diagnosis of aquaporin-4 antibody positive neuromyelitis optica spectrum disorder.
Ringelstein, M., Metz, I., Ruprecht, K., Koch, A., Rappold, J., Ingwersen, J., Mathys, C., Jarius, S., Brück, W., Hartung, H.P., Paul, F. and Aktas, O.
Multiple Sclerosis Journal 20
(7): 882-888.
June 2014
Natural variation of histone modification and its impact on gene expression in the rat genome.
Rintisch, C., Heinig, M., Bauerfeind, A., Schafer, S., Mieth, C., Patone, G., Hummel, O., Chen, W., Cook, S., Cuppen, E., Colomé-Tatché, M., Johannes, F., Jansen, R.C., Neil, H., Werner, M., Pravenec, M., Vingron, M. and Hubner, N.
Genome Research 24
(6): 942-953.
June 2014
A robust estimation of exon expression to identify alternative spliced genes applied to human tissues and cancer samples.
Risueño, A., Roson-Burgo, B., Dolnik, A., Hernandez-Rivas, J.M., Bullinger, L. and De Las Rivas, J.
BMC Genomics 15
: 879.
8 October 2014
Design and analysis of Bar-seq experiments.
Robinson, D.G., Chen, W., Storey, J.D. and Gresham, D.
G3 4
(1): 11-18.
10 January 2014
NETs and cell cycle regulation.
Robson, M.I., Le Thanh, P. and Schirmer, E.C.
Advances in experimental medicine and biology 773
(773): 165-85.
1 January 2014
Characterization of genetic diversity in the nematode pristionchus pacificus from population-scale resequencing data.
Roedelsperger, C., Neher, R.A., Weller, A.M., Eberhardt, G., Witte, H., Mayer, W.E., Dieterich, C. and Sommer, R.J.
Genetics 196
(4): 1153-1165.
April 2014
Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice.
Rosendahl, A., Niemann, G., Lange, S., Ahadzadeh, E., Krebs, C., Contrepas, A., van Goor, H., Wiech, T., Bader, M., Schwake, M., Peters, J., Stahl, R., Nguyen, G. and Wenzel, U.O.
Laboratory Investigation 94
(8): 863-872.
August 2014
Photoreceptor layer thinning in idiopathic Parkinson's disease.
Roth, N.M., Saidha, S., Zimmermann, H., Brandt, A.U., Isensee, J., Benkhellouf-Rutkowska, A., Dornauer, M., Kühn, A.A., Mueller, T., Calabresi, P.A. and Paul, F.
Movement Disorders 29
(9): 1163-1170.
August 2014
Attenuated response of ICa,L to nitric oxide in atrial fibrillation.
Rozmaritsa, N., Christ, T., Van Wagoner, D.R., Haase, H., Stasch, J.P., Matschke, K. and Ravens, U.
Cardiovascular Research 101
(3): 533-542.
1 March 2014
Assessment of nonischemic fibrosis in hypertrophic cardiomyopathy: comparison of gadopentetate dimeglumine and gadobenate dimeglumine for enhanced cardiovascular magnetic resonance imaging.
Rudolph, A., von Knobelsdorff-Brenkenhoff, F., Wassmuth, R., Prothmann, M., Utz, W. and Schulz-Menger, J.
Journal of Magnetic Resonance Imaging 39
(5): 1153-1160.
May 2014
Multiple sclerosis: The elevated antibody response to Epstein-Barr virus primarily targets, but is not confined to, the glycine-alanine repeat of Epstein-Barr nuclear antigen-1.
Ruprecht, K., Wunderlich, B., Gieß, R., Meyer, P., Loebel, M., Lenz, K., Hofmann, J., Rosche, B., Wengert, O., Paul, F., Reimer, U. and Scheibenbogen, C.
Journal of Neuroimmunology 272
(1-2): 56-61.
15 July 2014
A variety of dicer substrates in human and C. elegans.
Rybak-Wolf, A., Jens, M., Murakawa, Y., Herzog, M., Landthaler, M. and Rajewsky, N.
Cell 159
(5): 1153-1167.
20 November 2014
Whole-mount in situ hybridization using DIG-labeled probes in planarian.
Rybak-Wolf, A. and Solana, J.
Methods in Molecular Biology 1211
: 41-51.
2014
A H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation.
Sabbattini, P., Sjoberg, M., Nikic, S., Frangini, A., Holmqvist, P.H., Kunowska, N., Carroll, T., Brookes, E., Arthur, S.J., Pombo, A. and Dillon, N.
Molecular Biology of the Cell 25
(6): 904-915.
March 2014
Single-cell RNA-seq: advances and future challenges.
Saliba, A.E., Westermann, A.J., Gorski, S.A. and Vogel, J.
Nucleic Acids Research 42
(14): 8845-8860.
18 August 2014
Essential role for autophagy during invariant NKT cell development.
Salio, M., Puleston, D.J., Mathan, T.S.M., Shepherd, D., Stranks, A.J., Adamopoulou, E., Veerapen, N., Besra, G.S., Hollander, G.A., Simon, A.K. and Cerundolo, V.
Proceedings of the National Academy of Sciences of the United States of America 111
(52): E5678-E5687.
30 December 2014
Increased mortality after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis and low ejection fraction: a meta-analysis of 6898 patients.
Sannino, A., Gargiulo, G., Schiattarella, G.G., Brevetti, L., Perrino, C., Stabile, E., Losi, M.A., Toscano, E., Giugliano, G., Scudiero, F., Chiacchio, E., Trimarco, B. and Esposito, G.
International Journal of Cardiology 176
(1): 32-39.
September 2014
Meta-analysis of mortality outcomes and mitral regurgitation evolution in 4,839 patients having transcatheter aortic valve implantation for severe aortic stenosis.
Sannino, A., Losi, M.A., Schiattarella, G.G., Gargiulo, G., Perrino, C., Stabile, E., Toscano, E., Giugliano, G., Brevetti, L., Franzone, A., Cirillo, P., Imbriaco, M., Trimarco, B. and Esposito, G.
American Journal of Cardiology 114
(6): 875-882.
15 September 2014
Oral administration of angiotensin-(1-7) ameliorates type 2 diabetes in rats.
Santos, S.H.S., Giani, J.F., Burghi, V., Miquet, J.G., Qadri, F., Braga, J.F., Todiras, M., Kotnik, K., Alenina, N., Dominici, F.P., Santos, R.A.S. and Bader, M.
Journal of Molecular Medicine 92
(3): 255-265.
March 2014
Simultaneous extraction of proteins and metabolites from cells in culture.
Sapcariu, S.C., Kanashova, T., Weindl, D., Ghelfi, J., Dittmar, G. and Hiller, K.
MethodsX 1
(1): 74-80.
18 July 2014
A missense mutation accelerating the gating of the lysosomal Cl(-)/H(+)-exchanger ClC-7/Ostm1 causes osteopetrosis with gingival hamartomas in cattle.
Sartelet, A., Stauber, T., Coppieters, W., Ludwig, C.F., Fasquelle, C., Druet, T., Zhang, Z., Ahariz, N., Cambisano, N., Jentsch, T.J. and Charlier, C.
Disease Models & Mechanisms 7
(1): 119-128.
January 2014
SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia.
Sasca, D., Hähnel, P.S., Szybinski, J., Khawaja, K., Kriege, O., Pante, S.V., Bullinger, L., Strand, S., Strand, D., Theobald, M. and Kindler, T.
Blood 124
(1): 121-133.
3 July 2014
Immunogen design to focus the B-cell repertoire.
Sattentau, Q.J.
Current Opinion in HIV and AIDS 9
(3): 217-223.
May 2014
Novel RNA modifications in the nervous system: form and function.
Satterlee, J.S., Basanta-Sanchez, M., Blanco, S., Li, J.B., Meyer, K., Pollock, J., Sadri-Vakili, G. and Rybak-Wolf, A.
Journal of Neuroscience 34
(46): 15170-15177.
12 November 2014
Interferon gamma signaling positively regulates hematopoietic stem cell emergence.
Sawamiphak, S., Kontarakis, Z. and Stainier, D.Y.R.
Developmental Cell 31
(5): 640-653.
8 December 2014
Changes in metabolite profiles caused by genetically determined obesity in mice.
Schaefer, N., Yu, Z., Wagener, A., Millrose, M.K., Reissmann, M., Bortfeldt, R., Dieterich, C., Adamski, J., Wang-Sattler, R., Illig, T. and Brockmann, G.A.
Metabolomics 10
(3): 461-472.
June 2014
Retinal nerve fibre layer thickness correlates with brain white matter damage in multiple sclerosis: a combined optical coherence tomography and diffusion tensor imaging study.
Scheel, M., Finke, C., Oberwahrenbrock, T., Freing, A., Pech, L.M., Schlichting, J., Sömmer, C., Wuerfel, J., Paul, F. and Brandt, A.U.
Multiple Sclerosis Journal 20
(14): 1904-1907.
December 2014
Refocussing antibody responses by chemical modification of vaccine antigens.
Schiffner, T., Leonavicius, K., Schuster, H., Kim, H.J., Kong, L., Saliba, R., Brod, F., Wegmann, F., Huang, P.S., Stewart-Jones, G.B., Schief, W.R., Ward, A.B., Moore, J.P., Sanders, R.W., Davis, B.G. and Sattentau, Q.J.
AIDS Research and Human Retroviruses 30
(S1): A66-A67.
October 2014
Relations of low contrast visual acuity, quality of life and multiple sclerosis functional composite: a cross-sectional analysis.
Schinzel, J., Zimmermann, H., Paul, F., Ruprecht, K., Hahn, K., Brandt, A.U. and Dörr, J.
BMC Neurology 14
: 31.
20 February 2014
Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.
Schleifenbaum, J., Kassmann, M., Szijártó, I.A., Hercule, H.C., Tano, J.Y., Weinert, S., Heidenreich, M., Pathan, A.R., Anistan, Y.M., Alenina, N., Rusch, N.J., Bader, M., Jentsch, T.J. and Gollasch, M.
Circulation Research 115
(2): 263-272.
7 July 2014
Differential impact of allelic ratio and insertion site in FLT3-ITD–positive AML with respect to allogeneic transplantation.
Schlenk, R.F., Kayser, S., Bullinger, L., Kobbe, G., Casper, J., Ringhoffer, M., Held, G., Brossart, P., Lübbert, M., Salih, H.R., Kindler, T., Horst, H.A., Wulf, G., Nachbaur, D., Götze, K., Lamparter, A., Paschka, P., Gaidzik, V.I., Teleanu, V., Späth, D., Benner, A., Krauter, J., Ganser, A., Döhner, H. and Döhner, K.
Blood 124
(23): 3441-3449.
27 November 2014
Proteasome inhibition slightly improves cardiac function in mice with hypertrophic cardiomyopathy.
Schlossarek, S., Singh, S., Geertz, B., Schulz, H., Reischmann, S., Hübner, N. and Carrier, L.
Frontiers in Physiology 5
: 484.
16 December 2014
The E3 ubiquitin ligase TRIM62 and inflammation-induced skeletal muscle atrophy.
Schmidt, F., Kny, M., Zhu, X., Wollersheim, T., Persicke, K., Langhans, C., Lodka, D., Kleber, C., Weber-Carstens, S. and Fielitz, J.
Critical Care 18
(5): 545.
29 September 2014
Bridging the Gap: Methods and Teaching of F-A-S-T - Framing-Art-Science-Technology.
Schmidt, D., Koalick, G., Gassel, S., Sery, C., Groh, R. and Wacker, M.
Lecture Notes in Computer Science 8517
: 589-600.
2014
Disproportional decrease in office blood pressure compared with 24-hour ambulatory blood pressure with antihypertensive treatment: dependency on pretreatment blood pressure levels.
Schmieder, R.E., Schmidt, S.T., Riemer, T., Dechend, R., Hagedorn, I., Senges, J., Messerli, F.H. and Zeymer, U.
Hypertension 64
(5): 1067-1072.
November 2014
Minocycline protects the immature white matter against hyperoxia.
Schmitz, T., Krabbe, G., Weikert, G., Scheuer, T., Matheus, F., Wang, Y., Mueller, S., Kettenmann, H., Matyash, V., Bührer, C. and Endesfelder, S.
Experimental Neurology 254
: 153-165.
April 2014
Leukemic stem cells of acute myeloid leukemia patients carrying NPM1 mutation are candidates for targeted immunotherapy.
Schneider, V., Zhang, L., Bullinger, L., Rojewski, M., Hofmann, S., Wiesneth, M., Schrezenmeier, H., Götz, M., Botzenhardt, U., Barth, T.F.E., Döhner, K., Döhner, H. and Greiner, J.
Leukemia 28
(8): 1759-62.
August 2014
Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.
Schoors, S., De Bock, K., Cantelmo, A.R., Georgiadou, M., Ghesquière, B., Cauwenberghs, S., Kuchnio, A., Wong, B.W., Quaegebeur, A., Goveia, J., Bifari, F., Wang, X., Blanco, R., Tembuyser, B., Cornelissen, I., Bouché, A., Vinckier, S., Diaz-Moralli, S., Gerhardt, H., Telang, S., Cascante, M., Chesney, J., Dewerchin, M. and Carmeliet, P.
Cell Metabolism 19
(1): 37-48.
7 January 2014
Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor.
Schreier, B., Rabe, S., Winter, S., Ruhs, S., Mildenberger, S., Schneider, B., Sibilia, M., Gotthardt, M., Kempe, S., Mäder, K., Grossmann, C. and Gekle, M.
Scientific Reports 4
: 7430.
11 December 2014
Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair.
Schreml, S., Meier, R.J., Kirschbaum, M., Kong, S.C., Gehmert, S., Felthaus, O., Küchler, S., Sharpe, J.R., Wöltje, K., Weiß, K.T., Albert, M., Seidl, U., Schröder, J., Morsczeck, C., Prantl, L., Duschl, C., Pedersen, S.F., Gosau, M., Berneburg, M., Wolfbeis, O.S., Landthaler, M. and Babilas, P.
Theranostics 4
(7): 721-735.
July 2014
MicroRNA-138 is a potential regulator of memory performance in humans.
Schroeder, J., Ansaloni, S., Schilling, M., Liu, T., Radke, J., Jaedicke, M., Schjeide, B.M.M., Mashychev, A., Tegeler, C., Radbruch, H., Papenberg, G., Duezel, S., Demuth, I., Bucholtz, N., Lindenberger, U., Li, S.C., Steinhagen-Thiessen, E., Lill, C.M. and Bertram, L.
Frontiers in Human Neuroscience 8
: 501.
11 July 2014
Pacemaker current inhibition in experimental human cardiac sympathetic activation: a double-blind, randomized, crossover study.
Schroeder, C., Heusser, K., Zoerner, A.A., Großhennig, A., Wenzel, D., May, M., Sweep, F.C.G.J., Mehling, H., Luft, F.C., Tank, J. and Jordan, J.
Clinical Pharmacology and Therapeutics 95
(6): 601-607.
June 2014
Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.
Schubert, J., Siekierska, A., Langlois, M., May, P., Huneau, C., Becker, F., Muhle, H., Suls, A., Lemke, J.R., de Kovel, C.G.F., Thiele, H., Konrad, K., Kawalia, A., Toliat, M.R., Sander, T., Rueschendorf, F., Caliebe, A., Nagel, I., Kohl, B., Kecskes, A., Jacmin, M., Hardies, K., Weckhuysen, S., Riesch, E., Dorn, T., Brilstra, E.H., Baulac, S., Moller, R.S., Hjalgrim, H., Koeleman, B.P.C., Jurkat-Rott, K., Lehman-Horn, F., Roach, J.C., Glusman, G., Hood, L., Galas, D.J., Martin, B., de Witte, P.A.M., Biskup, S., De Jonghe, P., Helbig, I., Balling, R., Nuernberg, P., Crawford, A.D., Esguerra, C.V., Weber, Y.G. and Lerche, H.
Nature Genetics 46
(12): 1327-1332.
December 2014
Differential protein occupancy profiling of the mRNA transcriptome.
Schueler, M., Munschauer, M., Gregersen, L.H., Finzel, A., Loewer, A., Chen, W., Landthaler, M. and Dieterich, C.
Genome Biology 15
(1): R15.
13 January 2014
Roquin binding to target mRNAs involves a winged helix-turn-helix motif.
Schuetz, A., Murakawa, Y., Rosenbaum, E., Landthaler, M. and Heinemann, U.
Nature Communications 5
: 5701.
11 December 2014
Clostridium difficile toxin CDT hijacks microtubule organization and reroutes vesicle traffic to increase pathogen adherence.
Schwan, C., Kruppke, A.S., Nölke, T., Schumacher, L., Koch-Nolte, F., Kudryashev, M., Stahlberg, H. and Aktories, K.
Proceedings of the National Academy of Sciences of the United States of America 111
(6): 2313-2318.
11 February 2014
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites.
Schwartz, S., Mumbach, M.R., Jovanovic, M., Wang, T., Maciag, K., Bushkin, G.G., Mertins, P., Ter-Ovanesyan, D., Habib, N., Cacchiarelli, D., Sanjana, N.E., Freinkman, E., Pacold, M.E., Satija, R., Mikkelsen, T.S., Hacohen, N., Zhang, F., Carr, S.A., Lander, E.S. and Regev, A.
Cell Reports 8
(1): 284-296.
10 July 2014
Phylogenetic quantification of intra-tumour heterogeneity.
Schwarz, R.F., Trinh, A., Sipos, B., Brenton, J.D., Goldman, N. and Markowetz, F.
PLoS Computational Biology 10
(4): e1003535.
17 April 2014
Deciphering the genetic basis of microcystin tolerance.
Schwarzenberger, A., Sadler, T., Motameny, S., Ben-Khalifa, K., Frommolt, P., Altmüller, J., Konrad, K. and von Elert, E.
BMC Genomics 15
: 776.
9 September 2014
Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model.
Schwarzer, R., Nickel, N., Godau, J., Willie, B.M., Duda, G.N., Schwarzer, R., Cirovic, B., Leutz, A., Manz, R., Bogen, B., Dörken, B. and Jundt, F.
Blood Cancer Journal 4
: e217.
13 June 2014
The E3-ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu.
Schweiger, S., Dorn, S., Fuchs, M., Köhler, A., Matthes, F., Müller, E.C., Wanker, E., Schneider, R. and Krauß, S.
Journal of Biological Chemistry 289
(46): 31805-31817.
14 November 2014
Dual linkage of a locus to left ventricular mass and a cardiac gene co-expression network driven by a chromosome domain.
Scott-Boyer, M.P., Praktiknjo, S.D., Llamas, B., Picard, S. and Deschepper, C.F.
Frontiers in Cardiovascular Medicine 1
: 11.
10 December 2014
Low-dose nitrite alleviates early effects of an X-ray contrast medium on renal hemodynamics and oxygenation in rats.
Seeliger, E., Cantow, K., Arakelyan, K., Ladwig, M., Persson, P.B. and Flemming, B.
Investigative Radiology 49
(2): 70-77.
February 2014
Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production.
Selley, E., Kun, S., Szijártó, I.A., Laczy, B., Kovacs, T., Fueloep, F., Wittmann, I. and Molnar, G.A.
Cardiovascular Diabetology 13
(1): 69.
2 April 2014
Bacteriophage P22 tailspike: structure of the complete protein and function of the interdomain linker.
Seul, A., Müller, J.J., Andres, D., Stettner, E., Heinemann, U. and Seckler, R.
Acta Crystallographica Section D 70
(Pt 5): 1336-1345.
May 2014
Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2.
Shah, C., Hegde, B.G., Morén, B., Behrmann, E., Mielke, T., Moenke, G., Spahn, C.M., Lundmark, R., Daumke, O. and Langen, R.
Structure 22
(3): 409-420.
4 March 2014
Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform.
Sharma, A., Marceau, C., Hamaguchi, R., Burridge, P.W., Rajarajan, K., Churko, J.M., Wu, H., Sallam, K.I., Matsa, E., Sturzu, A.C., Che, Y., Ebert, A., Diecke, S., Liang, P., Red-Horse, K., Carette, J.E., Wu, S.M. and Wu, J.C.
Circulation Research 115
(6): 556-66.
29 August 2014
Experimental applications of TNF-reporter mice with far-red fluorescent label.
Shebzukhov, Y.V., Kuchmiy, A.A., Kruglov, A.A., Zipp, F., Siffrin, V. and Nedospasov, S.A.
Methods in Molecular Biology 1155
: 151-162.
10 April 2014
Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.
Sheean, M.E., McShane, E., Cheret, C., Walcher, J., Müller, T., Wulf-Goldenberg, A., Hoelper, S., Garratt, A.N., Krüger, M., Rajewsky, K., Meijer, D., Birchmeier, W., Lewin, G.R., Selbach, M. and Birchmeier, C.
Genes & Development 28
(3): 290-303.
1 February 2014
Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens.
Sheppard, N.C., Brinckmann, S.A., Gartlan, K.H., Puthia, M., Svanborg, C., Krashias, G., Eisenbarth, S.C., Flavell, R.A., Sattentau, Q.J. and Wegmann, F.
International Immunology 26
(10): 531-538.
October 2014
Pancreas development ex vivo: culturing embryonic pancreas explants on permeable culture inserts, with fibronectin-coated glass microwells, or embedded in three-dimensional Matrigel(TM).
Shih, H.P. and Sander, M.
Methods in Molecular Biology 1210
: 229-37.
1 January 2014
Inhibition of protein geranylgeranylation specifically interferes with CD40-dependent B cell activation, resulting in a reduced capacity to induce T cell immunity.
Shimabukuro-Vornhagen, A., Zoghi, S., Liebig, T.M., Wennhold, K., Chemitz, J., Draube, A., Kochanek, M., Blaschke, F., Pallasch, C., Holtick, U., Scheid, C., Theurich, S., Hallek, M. and von Bergwelt-Baildon, M.S.
Journal of Immunology 193
(10): 5294-5305.
15 November 2014
Analysis of expressed genes of the bacterium 'Candidatus Phytoplasma mali' highlights key features of virulence and metabolism.
Siewert, C., Luge, T., Duduk, B., Seemüller, E., Büttner, C., Sauer, S. and Kube, M.
PLOS ONE 9
(4): e94391.
11 April 2014
How to treat tumefactive demyelinating disease?
Siffrin, V., Müller-Forell, W., von Pein, H. and Zipp, F.
Multiple Sclerosis Journal 20
(5): 631-633.
April 2014
Recessive mutations in PCBD1 cause a new type of early-onset diabetes.
Simaite, D., Kofent, J., Gong, M., Rüschendorf, F., Jia, S., Arn, P., Bentler, K., Ellaway, C., Kühnen, P., Hoffmann, G.F., Blau, N., Spagnoli, F.M., Hübner, N. and Raile, K.
Diabetes 63
(10): 3557-3564.
October 2014
Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways.
Simonetti, M., Agarwal, N., Stösser, S., Bali, K.K., Karaulanov, E., Kamble, R., Pospisilova, B., Kurejova, M., Birchmeier, W., Niehrs, C., Heppenstall, P. and Kuner, R.
Neuron 83
(1): 104-121.
2 July 2014
Peripheral blood sCD3(-) CD4(+) T cells: a useful diagnostic tool in angioimmunoblastic T cell lymphoma.
Singh, A., Schabath, R., Ratei, R., Stroux, A., Klemke, C.D., Nebe, T., Flörcken, A., van Lessen, A., Anagnostopoulos, I., Dörken, B., Ludwig, W.D., Pezzutto, A. and Westermann, J.
Hematological Oncology 32
(1): 16-21.
March 2014
Genome-wide analysis of trans-splicing in the nematode Pristionchus pacificus unravels conserved gene functions for germline and dauer development in divergent operons.
Sinha, A., Langnick, C., Sommer, R.J. and Dieterich, C.
RNA 20
(9): 1386-1397.
September 2014
α-smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study.
Sinn, M., Denkert, C., Striefler, J.K., Pelzer, U., Stieler, J.M., Bahra, M., Lohneis, P., Doerken, B., Oettle, H., Riess, H. and Sinn, B.V.
British Journal of Cancer 111
(10): 1917-1923.
11 November 2014
SPARC expression in resected pancreatic cancer patients treated with Gemcitabine: results from the CONKO-001 study.
Sinn, M., Sinn, B.V., Striefler, J.K., Lindner, J.L., Stieler, J.M., Lohneis, P., Bischoff, S., Blaeker, H., Pelzer, U., Neuhaus, P., Dietel, M., Doerken, B., Oettle, H., Riess, H. and Denkert, C.
Annals of Oncology 25
(5): 1025-1032.
May 2014
Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption.
Slimak, M.A., Ables, J.L., Frahm, S., Antolin-Fontes, B., Santos-Torres, J., Moretti, M., Gotti, C. and Ibanez-Tallon, I.
Frontiers in Human Neuroscience 8
: 12.
27 January 2014
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
Sonnet, M., Claus, R., Becker, N., Zucknick, M., Petersen, J., Lipka, D.B., Oakes, C.C., Andrulis, M., Lier, A., Milsom, M.D., Witte, T., Gu, L., Kim-Wanner, S.Z., Schirmacher, P., Wulfert, M., Gattermann, N., Lübbert, M., Rosenbauer, F., Rehli, M., Bullinger, L., Weichenhan, D. and Plass, C.
Genome Medicine 6
(4): 34.
2014
Receptor Mas protects mice against hypothermia and mortality induced by endotoxemia.
Souza, L.L., Duchene, J., Todiras, M., Azevedo, L.C.P., Costa-Neto, C.M., Alenina, N., Santos, R.A. and Bader, M.
Shock 41
(4): 331-336.
April 2014
Distribution of non-AT(1), non-AT(2) binding of (125)I-Sarcosine(1), Isoleucine(8) angiotensin II in neurolysin knockout mouse brains.
Speth, R.C., Carrera, E.J., Bretón, C., Linares, A., Gonzalez-Reiley, L., Swindle, J.D., Santos, K.L., Schadock, I., Bader, M. and Karamyan, V.T.
PLoS ONE 9
(8): e105762.
22 August 2014
C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder.
Spitzer, C., Wibisono, D., Terfehr, K., Loewe, B., Otte, C. and Wingenfeld, K.
Nordic Journal of Psychiatry 68
(5): 296-299.
July 2014
Catabolic signaling and muscle wasting after acute ischemic stroke in mice: indication for a stroke-specific sarcopenia.
Springer, J., Schuster, S., Peske, K., Tschirner, A., Rex, A., Engel, O., Scherbakov, N., Meisel, A., von Haehling, S., Boschmann, M., Anker, S.D., Dirnagl, U. and Doehner, W.
Stroke 45
(12): 3675-3683.
December 2014
Cerebral embolic lesions detected with diffusion-weighted magnetic resonance imaging following carotid artery stenting: a meta-analysis of 8 studies comparing filter cerebral protection and proximal balloon occlusion.
Stabile, E., Sannino, A., Schiattarella, G.G., Gargiulo, G., Toscano, E., Brevetti, L., Scudiero, F., Giugliano, G., Perrino, C., Trimarco, B. and Esposito, G.
JACC: Cardiovascular Interventions 7
(10): 1177-1183.
October 2014
CellFinder: a cell data repository.
Stachelscheid, H., Seltmann, S., Lekschas, F., Fontaine, J.F., Mah, N., Neves, M., Andrade-Navarro, M.A., Leser, U. and Kurtz, A.
Nucleic Acids Research 42
(1): D950-D958.
1 January 2014
The leukemogenicity of Hoxa9 depends on alternative splicing.
Stadler, C R, Vegi, N, Mulaw, M A, Edmaier, K E, Rawat, V P S, Dolnik, A, Bullinger, L., Heilmeier, B, Quintanilla-Fend, L, Spiekermann, K, Hiddemann, W, Döhner, K, Döhner, H, Feuring-Buske, M and Buske, C
Leukemia 28
(9): 1838-1843.
September 2014
Preeclampsia and uteroplacental acute atherosis: immune and inflammatory factors.
Staff, A.C., Johnsen, G.M., Dechend, R. and Redman, C.W.G.
Journal of Reproductive Immunology 101-102
: 120-126.
February 2014
Social stress increases expression of hemoglobin genes in mouse prefrontal cortex.
Stankiewicz, A.M., Goscik, J., Swiergiel, A.H., Majewska, A., Wieczorek, M., Juszczak, G.R. and Lisowski, P.
BMC Neuroscience 15
(1): 130.
4 December 2014
Glatiramer acetate (Copaxone) modulates platelet activation and inhibits thrombin-induced calcium influx: Possible role of copaxone in targeting platelets during autoimmune neuroinflammation.
Starossom, S.C., Veremeyko, T., Dukhinova, M., Yung, A.W.Y. and Ponomarev, E.D.
PLoS ONE 9
(5): e96256.
2 May 2014
Weight change later in life and colon and rectal cancer risk in participants in the EPIC-PANACEA study.
Steins Bisschop, C.N., van Gils, C.H., Emaus, M.J., Bueno-de-Mesquita, H.B., Monninkhof, E.M., Boeing, H., Aleksandrova, K., Jenab, M., Norat, T., Riboli, E., Boutron-Rualt, M.C., Fagherazzi, G., Racine, A., Palli, D., Krogh, V., Tumino, R., Naccarati, A., Mattiello, A., Argüelles, M.V., Sanchez, M.J., Tormo, M.J., Ardanaz, E., Dorronsoro, M., Bonet, C.w, Khaw, K.T., Key, T., Trichopoulou, A., Orfanos, P., Naska, A., Kaaks, R.R., Lukanova, A., Pischon, T., Ljuslinder, I., Jirström, K., Ohlsson, B., Overvad, K., Landsvig Berentzen, T., Halkjaer, J., Tjonneland, A., Weiderpass, E., Skeie, G., Braaten, T., Siersema, P.D., Freisling, H., Ferrari, P., Peeters, P.H.M. and May, A.M.
American Journal of Clinical Nutrition 99
(1): 139-147.
January 2014
Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.
Stilgenbauer, S., Schnaiter, A., Paschka, P., Zenz, T., Rossi, M., Döhner, K., Bühler, A., Böttcher, S., Ritgen, M., Kneba, M., Winkler, D., Tausch, E., Hoth, P., Edelmann, J., Mertens, D., Bullinger, L., Bergmann, M., Kless, S., Mack, S., Jäger, U., Patten, N., Wu, L., Wenger, M.K., Fingerle-Rowson, G., Lichter, P., Cazzola, M., Wendtner, C.M., Fink, A.M., Fischer, K., Busch, R., Hallek, M. and Döhner, H.
Blood 123
(21): 3247-3254.
22 May 2014
The capsaicin receptor TRPV1 as a novel modulator of neural precursor cell proliferation.
Stock, K., Garthe, A., de Almeida Sassi, F., Glass, R., Wolf, S.A. and Kettenmann, H.
Stem Cells 32
(12): 3183-3195.
December 2014
Exercise capacity and N-terminal pro-brain natriuretic peptide levels with biventricular vs. right ventricular pacing for atrioventricular block: results from the PREVENT-HF German Substudy.
Stockburger, M., de Teresa, E., Lamas, G., Desaga, M., Koenig, C., Habedank, D., Cobo, E., Navarro, X. and Wiegand, U.
Europace 16
(1): 63-70.
January 2014
Global characterization of the oocyte-to-embryo transition in Caenorhabditis elegans uncovers a novel mRNA clearance mechanism.
Stoeckius, M., Grün, D., Kirchner, M., Ayoub, S., Torti, F., Piano, F., Herzog, M., Selbach, M. and Rajewsky, N.
EMBO Journal 33
(16): 1751-1766.
18 August 2014
Paternal RNA contributions in the Caenorhabditis elegans zygote.
Stoeckius, M., Grün, D. and Rajewsky, N.
EMBO Journal 33
(16): 1740-1750.
18 August 2014
Immunotherapy with TCR-redirected T cells: comparison of TCR-transduced and TCR-engineered hematopoietic stem cell-derived T cells.
Stärck, L., Popp, K., Pircher, H. and Uckert, W.
Journal of Immunology 192
(1): 206-213.
1 January 2014
Length polymorphism of the B2-VNTR minisatellite repeat of the bradykinin B2 receptor gene in healthy Russians and patients with
coronary heart disease.
Suchkova, I.O., Pavlinova, L.I., Larionova, E.E., Alenina, N.V., Solovyov, K.V., Baranova, T.V., Belotserkovskaya, E.V., Sasina, L.K., Bader, M., Denisenko, A.D., Mustafina, O.E., Khusnutdinova, E.K. and Patkin, E.L.
Molecular Biology 48
(5): 655-663.
September 2014
ClC-7 expression levels critically regulate bone turnover, but not gastric acid secretion.
Supanchart, C., Wartosch, L., Schlack, C., Kühnisch, J., Giehl, M., Felsenberg, D., Fuhrmann, J.C., de Vernejoul, M.C., Jentsch, T.J. and Kornak, U.
Bone 58
: 92-102.
January 2014
Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
Suratanee, A., Schaefer, M.H., Betts, M.J., Soons, Z., Mannsperger, H., Harder, N., Oswald, M., Gipp, M., Ramminger, E., Marcus, G., Männer, R., Rohr, K., Wanker, E., Russell, R.B., Andrade-Navarro, M.A., Eils, R. and König, R.
PLoS Computational Biology 10
(9): e1003814.
25 September 2014
In vivo stable isotope labeling by amino acids in Drosophila melanogaster.
Sury, M.D., Chen, J.X. and Selbach, M.
Methods in Molecular Biology 1188
: 85-93.
8 July 2014
Polar bear encephalitis: establishment of a comprehensive next-generation pathogen analysis pipeline for captive and free-living wildlife.
Szentiks, C.A., Tsangaras, K., Abendroth, B., Scheuch, M., Stenglein, M.D., Wohlsein, P., Heeger, F., Hoeveler, R., Chen, W., Sun, W., Damiani, A., Nikolin, V., Gruber, A.D., Grobbel, M., Kalthoff, D., Hoeper, D., Czirjak, G.A., DeRisi, J., Mazzoni, C.J., Schuele, A., Aue, A., East, M.L., Hofer, H., Beer, M., Osterrieder, N. and Greenwood, A.D.
Journal of Comparative Pathology 150
(4): 474-488.
May 2014
Elevated vascular level of ortho-tyrosine contributes to the impairment of insulin-induced arterial relaxation.
Szijártó, I.A., Molnár, G.A., Mikolás, E., Fisi, V., Cseh, J., Laczy, B., Kovács, T., Böddi, K., Takátsy, A., Gollasch, M., Koller, A. and Wittmann, I.
Hormone and Metabolic Research 46
(11): 749-752.
October 2014
Increase in insulin-induced relaxation of consecutive arterial segments toward the periphery: role of vascular oxidative state.
Szijártó, I.A., Molnár, G.A., Mikolás, E., Fisi, V., Laczy, B., Gollasch, M., Koller, A. and Wittmann, I.
Free Radical Research 48
(7): 749-757.
17 March 2014
Toxicological effect of single contaminants and contaminant mixtures associated with plant ingredients in novel salmon feeds.
Søfteland, L., Kirwan, J.A., Hori, T.S.F., Størseth, T.R., Sommer, U., Berntssen, M.H.G., Viant, M.R., Rise, M.L., Waagbø, R., Torstensen, B.E., Booman, M. and Olsvik, P.A.
Food and Chemical Toxicology 73
: 157-174.
November 2014
Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes.
Tank, J., da Costa-Goncalves, A.C., Kamer, I., Qadri, F., Ubhi, K., Rockenstein, E., Diedrich, A., Masliah, E., Gross, V. and Jordan, J.
Physiological Reports 2
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26 November 2014
Hypoxia and ischemia-reperfusion: a B(i)K contribution?
Tano, J.Y. and Gollasch, M.
American Journal of Physiology Heart and Circulatory Physiology 307
(6): H811-H817.
15 September 2014
Perivascular adipose tissue, potassium channels, and vascular dysfunction.
Tano, J.Y., Schleifenbaum, J. and Gollasch, M.
Arteriosclerosis Thrombosis and Vascular Biology 34
(9): 1827-1830.
September 2014
Argonaute2 mediates compensatory expansion of the pancreatic β cell.
Tattikota, S.G., Rathjen, T., McAnulty, S.J., Wessels, H.H., Akerman, I., van de Bunt, M., Hausser, J., Esguerra, J.L.S., Musahl, A., Pandey, A.K., You, X., Chen, W., Herrera, P.L., Johnson, P.R., O'Carroll, D., Eliasson, L., Zavolan, M., Gloyn, A.L., Ferrer, J., Shalom-Feuerstein, R., Aberdam, D. and Poy, M.N.
Cell Metabolism 19
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7 January 2014
Bifurcation of axons from cranial sensory neurons is disabled in the absence of Npr2-induced cGMP signaling.
Ter-Avetisyan, G., Rathjen, F.G. and Schmidt, H.
Journal of Neuroscience 34
(3): 737-747.
15 January 2014
Comparison of chimerism and minimal residual disease monitoring for relapse prediction after allogeneic stem cell transplantation for adult acute lymphoblastic leukemia.
Terwey, T.H., Hemmati, P.G., Nagy, M., Pfeifer, H., Goekbuget, N., Brueggemann, M., Le Duc, T.M., le Coutre, P., Doerken, B. and Arnold, R.
Biology of Blood and Marrow Transplantation 20
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October 2014
Efficacy of CAR T-cell therapy in large tumors relies upon stromal targeting by IFNγ.
Textor, A., Listopad, J.J., Wührmann, L.L., Perez, C., Kruschinski, A., Chmielewski, M., Abken, H., Blankenstein, T. and Charo, J.
Cancer Research 74
(23): 6796-6805.
1 December 2014
Combining photonic crystal and optical Monte Carlo simulations: implementation, validation and application in a positron emission tomography detector.
Thalhammer, C., Breuer, J., Fuehrer, T., Popescu, A., Hedler, H., Walther, T. and Niendorf, T.
IEEE Transactions on Nuclear Science 61
(6): 3618-3626.
December 2014
Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes.
Thelen, M., Razquin, C., Hernandez, I., Gorostidi, A., Sanchez-Valle, R., Ortega-Cubero, S., Wolfsgruber, S., Drichel, D., Fliessbach, K., Duenkel, T., Damian, M., Heilmann, S., Slotosch, A., Lennarz, M., Seijo-Martinez, M., Rene, R., Kornhuber, J., Peters, O., Luckhaus, C., Jahn, H., Huell, M., Ruether, E., Wiltfang, J., Lorenzo, E., Gascon, J., Lleo, A., Llado, A., Campdelacreu, J., Moreno, F., Ahmadzadehfar, H., Fortea, J., Indakoetxea, B., Heneka, M.T., Wetter, A., Pastor, M.A., Riverol, M., Becker, T., Froelich, L., Tarraga, L., Boada, M., Wagner, M., Jessen, F., Maier, W., Clarimon, J., Lopez de Munain, A., Ruiz, A., Pastor, P. and Ramirez, A.
Neurobiology of Aging 35
(11): 2657.e13-2657.e19.
November 2014
High glucose modifies transient receptor potential canonical type 6 channels via increased oxidative stress and syndecan-4 in human podocytes.
Thilo, F., Lee, M., Xia, S., Zakrzewicz, A. and Tepel, M.
Biochemical and Biophysical Research Communications 450
(1): 312-317.
18 July 2014
Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes.
Thurley, K., Tovey, S.C., Moenke, G., Prince, V.L., Meena, A., Thomas, A.P., Skupin, A., Taylor, C.W. and Falcke, M.
Science Signaling 7
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24 June 2014
Identifying dynamic membrane structures with atomic-force microscopy and confocal imaging.
Timmel, T., Schuelke, M. and Spuler, S.
Microscopy and Microanalysis 20
(2): 514-520.
April 2014
Taking another "look" at sodium.
Titze, J., Müller, D.N. and Luft, F.C.
Canadian Journal of Cardiology 30
(5): 473-475.
May 2014
A phylogeny-based benchmarking test for orthology inference reveals the limitations of function-based validation.
Trachana, K., Forslund, K., Larsson, T., Powell, S., Doerks, T., von Mering, C. and Bork, P.
PLoS ONE 9
(11): e111122.
4 November 2014
CDK5 is a major regulator of the tumor suppressor DLC1.
Tripathi, B.K., Qian, X., Mertins, P., Wang, D., Papageorge, A.G., Carr, S.A. and Lowy, D.R.
Journal of Cell Biology 207
(5): 627-642.
8 December 2014
High prevalence of immunoglobulin light chain gene aberrations as revealed by FISH in multiple myeloma and MGUS.
Tuerkmen, S., Binder, A., Gerlach, A., Niehage, S., Melissari, M.T., Inandiklioglu, N., Doerken, B. and Burmeister, T.
Genes Chromosomes & Cancer 53
(8): 650-656.
August 2014
Genomic analysis of Sleeping Beauty transposon integration in human somatic cells.
Turchiano, G., Latella, M.C., Gogol-Döring, A., Cattoglio, C., Mavilio, F., Izsvák, Z., Ivics, Z. and Recchia, A.
PLoS ONE 9
(11): e112712.
12 November 2014
B-cell-intrinsic STAT6 signaling controls germinal center formation.
Turqueti-Neves, A., Otte, M., da Costa, O.P., Höpken, U.E., Lipp, M., Buch, T. and Voehringer, D.
European Journal of Immunology 44
(7): 2130-2138.
July 2014
Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.
Vaeth, M., Mueller, G., Stauss, D., Dietz, L., Klein-Hessling, S., Serfling, E., Lipp, M., Berberich, I. and Berberich-Siebelt, F.
Journal of Experimental Medicine 211
(3): 545-561.
10 March 2014
Antitumor efficacy, pharmacokinetic and biodistribution studies of the anticancer peptide CIGB-552 in mouse models.
Vallespi, M.G., Pimentel, G., Cabrales-Rico, A., Garza, J., Oliva, B., Mendoza, O., Gomez, Y., Basaco, T., Sanchez, I., Calderon, C., Rodriguez, J.C., Markelova, M.R., Fichtner, I., Astrada, S., Bollati-Fogolín, M., Garay, H.E. and Reyes, O.
Journal of Peptide Science 20
(11): 850-859.
November 2014
Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity.
Verschuere, T., Toelen, J., Maes, W., Poirier, F., Boon, L., Tousseyn, T., Mathivet, T., Gerhardt, H., Mathieu, V., Kiss, R., Lefranc, F., Van Gool, S.W. and De Vleeschouwer, S.
International Journal of Cancer 134
(4): 873-884.
15 February 2014
Diazoxide attenuates autoimmune encephalomyelitis and modulates lymphocyte proliferation and dendritic cell functionality.
Virgili, N., Mancera, P., Chanvillard, C., Wegner, A., Wappenhans, B., Rodríguez, M.J., Infante-Duarte, C., Espinosa-Parrilla, J.F. and Pugliese, M.
Journal of Neuroimmune Pharmacology 9
(4): 558-568.
September 2014
Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss, F.K., Ullrich, F., Muench, J., Lazarow, K., Lutter, D., Mah, N., Andrade-Navarro, M.A., von Kries, J.P., Stauber, T. and Jentsch, T.J.
Science 344
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9 May 2014
Filaggrin deficiency leads to impaired lipid profile and altered acidification pathways in a 3D skin construct.
Vávrová, K., Henkes, D., Strüver, K., Sochorová, M., Školová, B., Witting, M.Y., Friess, W., Schreml, S., Meier, R.J., Schäfer-Korting, M., Fluhr, J.W. and Küchler, S.
The Journal of Investigative Dermatology 134
(3): 746-753.
March 2014
Vinculin binding angle in podosomes revealed by high resolution microscopy.
Walde, M., Monypenny, J., Heintzmann, R., Jones, G.E. and Cox, S.
PLoS ONE 9
(2): e88251.
11 February 2014
Ultrahigh field magnetic resonance and colour Doppler real-time fusion imaging of the orbit - a hybrid tool for assessment of choroidal melanoma.
Walter, U., Niendorf, T., Graessl, A., Rieger, J., Krüger, P.C., Langner, S., Guthoff, R.F. and Stachs, O.
European Radiology 24
(5): 1112-1117.
May 2014
In vitro and in vivo investigations into the carbene copper bromide anticancer drug candidate WBC4.
Walther, W., Fichtner, I., Hackenberg, F., Streciwilk, W. and Tacke, M.
Letters in Drug Design & Discovery 11
(7): 825-832.
August 2014
Crystal structure of the yeast TRAPP-associated protein Tca17.
Wang, C., Gohlke, U., Roske, Y. and Heinemann, U.
FEBS Journal 281
(18): 4195-4206.
September 2014
Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells.
Wang, J., Xie, G., Singh, M., Ghanbarian, A.T., Raskó, T., Szvetnik, A., Cai, H., Besser, D., Prigione, A., Fuchs, N.V., Schumann, G.G., Chen, W., Lorincz, M.C., Ivics, Z., Hurst, L.D. and Izsvák, Z.
Nature 516
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18 December 2014
Suicidal autointegration of Sleeping Beauty and piggyBac transposons in eukaryotic cells.
Wang, Y., Wang, J., Devaraj, A., Singh, M., Jimenez Orgaz, A., Chen, J.X., Selbach, M., Ivics, Z. and Izsvák, Z.
PLoS Genetics 10
(3): e1004103.
13 March 2014
Cardiac magnetic resonance imaging of congenital bicuspid aortic valves and associated aortic pathologies in adults.
Wassmuth, R., von Knobelsdorff-Brenkenhoff, F., Gruettner, H., Utz, W. and Schulz-Menger, J.
European Heart Journal - Cardiovascular Imaging 15
(6): 673-679.
June 2014
Placental miR-1301 is dysregulated in early-onset preeclampsia and inversely correlated with maternal circulating leptin.
Weedon-Fekjaer, M.S., Sheng, Y., Sugulle, M., Johnsen, G.M., Herse, F., Redman, C.W., Lyle, R., Dechend, R. and Staff, A.C.
Placenta 35
(9): 709-717.
September 2014
Generation of targeted mouse mutants by embryo microinjection of TALENs.
Wefers, B., Ortiz, O., Wurst, W. and Kühn, R.
Methods 69
(1): 94-101.
15 August 2014
PHOXTRACK-a tool for interpreting comprehensive datasets of post-translational modifications of proteins.
Weidner, C., Fischer, C. and Sauer, S.
Bioinformatics 30
(23): 3410-3411.
1 December 2014
Lemon balm extract causes potent antihyperglycemic and antihyperlipidemic effects in insulin-resistant obese mice.
Weidner, C., Wowro, S.J., Freiwald, A., Kodelja, V., Abdel-Aziz, H., Kelber, O. and Sauer, S.
Molecular Nutrition & Food Research 58
(4): 903-907.
April 2014
Transport activity and presence of ClC-7/Ostm1 complex account for different cellular functions.
Weinert, S., Jabs, S., Hohensee, S., Chan, W.L., Kornak, U. and Jentsch, T.J.
EMBO Reports 15
(7): 784-791.
1 July 2014
Modes of TAL effector-mediated repression.
Werner, J. and Gossen, M.
Nucleic Acids Research 42
(21): 13061-13073.
1 December 2014
uORFdb - a comprehensive literature database on eukaryotic uORF biology.
Wethmar, K., Barbosa-Silva, A., Andrade-Navarro, M.A. and Leutz, A.
Nucleic Acids Research 42
(1): D60-D67.
1 January 2014
Whole genome sequencing and methylome analysis of the wild guinea pig.
Weyrich, A., Schuellermann, T., Heeger, F., Jeschek, M., Mazzoni, C.J., Chen, W., Schumann, K. and Fickel, J.
BMC Genomics 15
(1): 1036.
28 November 2014
Further improvements to linear mixed models for genome-wide association studies.
Widmer, C., Lippert, C., Weissbrod, O., Fusi, N., Kadie, C., Davidson, R., Listgarten, J. and Heckerman, D.
Scientific Reports 4
: 6874.
12 November 2014
Serum metabolites related to cardiorespiratory fitness, physical activity energy expenditure, sedentary time and vigorous activity.
Wientzek, A., Floegel, A., Knüppel, S., Vigl, M., Drogan, D., Adamski, J., Pischon, T. and Boeing, H.
International Journal of Sport Nutrition and Exercise Metabolism 24
(2): 215-226.
April 2014
Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.
Wikman, H., Westphal, L., Schmid, F., Pollari, S., Kropidlowski, J., Sielaff-Frimpong, B., Glatzel, M., Matschke, J., Westphal, M., Iljin, K., Huhtala, H., Terracciano, L., Kallioniemi, A., Sauter, G., Mueller, V., Witzel, I., Lamszus, K., Kemming, D. and Pantel, K.
Oncotarget 5
(10): 3076-3087.
30 May 2014
Enhanced emotional empathy after mineralocorticoid receptor stimulation in women with borderline personality disorder and healthy women.
Wingenfeld, K., Kuehl, L.K., Janke, K., Hinkelmann, K., Dziobek, I., Fleischer, J., Otte, C. and Roepke, S.
Neuropsychopharmacology 39
(8): 1799-1804.
July 2014
Changes in neural network homeostasis trigger neuropsychiatric symptoms.
Winkelmann, A., Maggio, N., Eller, J., Caliskan, G., Semtner, M., Häussler, U., Jüttner, R., Dugladze, T., Smolinsky, B., Kowalczyk, S., Chronowska, E., Schwarz, G., Rathjen, F.G., Rechavi, G., Haas, C.A., Kulik, A., Gloveli, T., Heinemann, U. and Meier, J.C.
Journal of Clinical Investigation 124
(2): 696-711.
3 February 2014
Sustained release carrier for adenosine triphosphate as signaling molecule.
Wischke, C., Weigel, J., Bulavina, L. and Lendlein, A.
Journal of Controlled Release 195
: 86-91.
10 December 2014
Mood-congruent memory in depression - the influence of personal relevance and emotional context.
Wittekind, C.E., Terfehr, K., Otte, C., Jelinek, L., Hinkelmann, K. and Moritz, S.
Psychiatry Research 215
(3): 606-613.
30 March 2014
Calcium-buffering effects of gluconate and nucleotides, as determined by a novel fluorimetric titration method.
Woehler, A., Lin, K.H. and Neher, E.
Journal of Physiology 592
(22): 4863-4875.
15 November 2014
Polyglutamine-rich suppressors of huntingtin toxicity act upstream of hsp70 and sti1 in spatial quality control of amyloid-like proteins.
Wolfe, K.J., Ren, H.Y., Trepte, P. and Cyr, D.M.
PLoS ONE 9
(5): e95914.
14 May 2014
Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment.
Wolfsgruber, S., Wagner, M., Schmidtke, K., Froelich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F.M., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Pantel, J, Rienhoff, O., Ruether, E., Henn, F., Wiltfang, J., Maier, W., Kornhuber, J. and Jessen, F.
PLoS ONE 9
(7): e100812.
14 July 2014
Structural basis of Mos1 transposase inhibition by the anti-retroviral drug Raltegravir.
Wolkowicz, U.M., Morris, E.R., Robson, M., Trubitsyna, M. and Richardson, J.M.
ACS Chemical Biology 9
(3): 743-51.
21 March 2014
Dynamics of myosin degradation in intensive care unit-acquired weakness during severe critical illness.
Wollersheim, T., Woehlecke, J., Krebs, M., Hamati, J., Lodka, D., Luther-Schroeder, A., Langhans, C., Haas, K., Radtke, T., Kleber, C., Spies, C., Labeit, S., Schuelke, M., Spuler, S., Spranger, J., Weber-Carstens, S. and Fielitz, J.
Intensive Care Medicine 40
(4): 528-538.
15 February 2014
Cytochrome P450-generated metabolites derived from ω-3 fatty acids attenuate neovascularization.
Yanai, R., Mulki, L., Hasegawa, E., Takeuchi, K., Sweigard, H., Suzuki, J., Gaissert, P., Vavvas, D.G., Sonoda, K.H., Rothe, M., Schunck, W.H., Miller, J.W. and Connor, K.M.
Proceedings of the National Academy of Sciences of the United States of America 111
(26): 9603-9608.
1 July 2014
Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection.
Yardımcı, G.G., Frank, C.L., Crawford, G.E. and Ohler, U.
Nucleic Acids Research 42
(19): 11865-11878.
29 October 2014
Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.
Yilmaz, Z.B., Kofahl, B., Beaudette, P., Baum, K., Ipenberg, I., Weih, F., Wolf, J., Dittmar, G. and Scheidereit, C.
Cell Reports 9
(5): 1756-1769.
11 December 2014
Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.
Yoshida, T., Iwata, T., Takai, Y., Birchmeier, W., Yamato, M. and Okano, T.
Genes to Cells 19
(11): 842-852.
November 2014
G protein-coupled estrogen receptor 1 (GPER) mediates relaxation of coronary arteries via cAMP/PKA-dependent activation of MLCP.
Yu, X., Li, F., Klussmann, E., Stallone, J.N. and Han, G.
American Journal of Physiology Endocrinology and Metabolism 307
(4): E398-E407.
15 August 2014
Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia.
Yun, H., Damm, F., Yap, D., Schwarzer, A., Chaturvedi, A., Jyotsana, N., Lübbert, M., Bullinger, L., Döhner, K., Geffers, R., Aparicio, S., Humphries, R.K., Ganser, A. and Heuser, M.
Haematologica 99
(9): 1456-1464.
September 2014
Antagonistic regulation of p57(kip2) by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest.
Zalc, A., Hayashi, S., Auradé, F., Bröhl, D., Chang, T., Mademtzoglou, D., Mourikis, P., Yao, Z., Cao, Y., Birchmeier, C. and Relaix, F.
Development 141
(14): 2780-2790.
July 2014
Mapping sensory circuits by anterograde transsynaptic transfer of recombinant rabies virus.
Zampieri, N., Jessell, T.M. and Murray, A.J.
Neuron 81
(4): 766-778.
19 February 2014
The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis.
Zatula, N., Wiese, M., Bunzendahl, J., Birchmeier, W., Perske, C., Bleckmann, A. and Brembeck, F.H.
Oncotarget 5
(16): 6770-6787.
30 August 2014
Plasma membrane lipid-protein interactions affect signaling processes in sterol-biosynthesis mutants in Arabidopsis thaliana.
Zauber, H., Burgos, A., Garapati, P. and Schulze, W.X.
Frontiers in Plant Science 5
: 78.
18 March 2014
Potential of fecal microbiota for early-stage detection of colorectal cancer.
Zeller, G., Tap, J., Voigt, A.Y., Sunagawa, S., Kultima, J.R., Costea, P.I., Amiot, A., Boehm, J., Brunetti, F., Habermann, N., Hercog, R., Koch, M., Luciani, A., Mende, D.R., Schneider, M.A., Schrotz-King, P., Tournigand, C., Tran Van Nhieu, J., Yamada, T., Zimmermann, J., Benes, V., Kloor, M., Ulrich, C.M., von Knebel Doeberitz, M., Sobhani, I. and Bork, P.
Molecular Systems Biology 10
(11): 766.
28 November 2014
Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome.
Zemojtel, T., Koehler, S., Mackenroth, L., Jaeger, M., Hecht, J., Krawitz, P., Graul-Neumann, L., Doelken, S., Ehmke, N., Spielmann, M., Oien, N.C., Schweiger, M.R., Krueger, U., Frommer, G., Fischer, B., Kornak, U., Floettmann, R., Ardeshirdavani, A., Moreau, Y., Lewis, S.E., Haendel, M., Smedley, D., Horn, D., Mundlos, S. and Robinson, P.N.
Science Translational Medicine 6
(252): 252ra123.
3 September 2014
1-Year outcomes of hypertension management in 13,000 outpatients under practice conditions: Prospective 3A registry.
Zeymer, U., Dechend, R., Riemer, T., Kaiser, E., Senges, J., Pittrow, D. and Schmieder, R.E.
International Journal of Cardiology 176
(3): 589-594.
20 October 2014
Glucagonoma-induced acute heart failure.
Zhang, K., Lehner, L.J., Praeger, D., Baumann, G., Knebel, F., Quinkler, M. and Roepke, T.K.
Endocrinology Diabetes and Metabolism Case Reports 2014
: 140061.
2014
Proteogenomic characterization of human colon and rectal cancer.
Zhang, B., Wang, J., Wang, X., Zhu, J., Liu, Q., Shi, Z., Chambers, M.C., Zimmerman, L.J., Shaddox, K.F., Kim, S., Davies, S.R., Wang, S., Wang, P., Kinsinger, C.R., Rivers, R.C., Rodriguez, H., Townsend, R.R., Ellis, M.J.C., Carr, S.A., Tabb, D.L., Coffey, R.J., Slebos, R.J.C. and Liebler, D.C.
Nature 513
(7518): 382-387.
18 September 2014
Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor.
Zhao, X., Chen, Y., Zhu, Q., Huang, H., Teng, P., Zheng, K., Hu, X., Xie, B., Zhang, Z., Sander, M. and Qiu, M.
PLoS ONE 9
(10): e109171.
6 October 2014
Dissection of open chromatin domain formation by site specific recombination in Drosophila.
Zielke, T. and Saumweber, H.
Journal of Cell Science 127
(Pt 10): 2365-2375.
15 May 2014
Leucocyte telomere length as marker for cardiovascular ageing.
Zietzer, A. and Hillmeister, P.
Acta Physiologica 211
(2): 251-256.
June 2014
Formation of transient lamellipodia.
Zimmermann, J. and Falcke, M.
PLoS ONE 9
(2): e87638.
5 February 2014
Antidepressants, autonomic function and mortality in patients with coronary heart disease: data from the Heart and Soul Study.
Zimmermann-Viehoff, F., Kuehl, L.K., Danker-Hopfe, H., Whooley, M.A. and Otte, C.
Psychological Medicine 44
(14): 2975-2984.
October 2014
Epigenome-wide association studies without the need for cell-type composition.
Zou, J., Lippert, C., Heckerman, D., Aryee, M. and Listgarten, J.
Nature Methods 11
(3): 309-311.
March 2014
Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.
de Almeida, P.E., Meyer, E.H., Kooreman, N.G., Diecke, S., Dey, D., Sanchez-Freire, V., Hu, S., Ebert, A., Odegaard, J., Mordwinkin, N.M., Brouwer, T.P., Lo, D., Montoro, D.T., Longaker, M.T., Negrin, R.S. and Wu, J.C.
Nature Communications 5
: 3903.
30 May 2014
A 3-base pair deletion, c.9711_9713del, in DMD results in intellectual disability without muscular dystrophy.
de Brouwer, A.P.M., Nabuurs, S.B., Verhaart, I.E.C., Oudakker, A.R., Hordijk, R., Yntema, H.G., Hordijk-Hos, J.M., Voesenek, K., de Vries, B.B.A., van Essen, T., Chen, W., Hu, H., Chelly, J., den Dunnen, J.T., Kalscheuer, V.M., Aartsma-Rus, A.M., Hamel, B.C.J., van Bokhoven, H. and Kleefstra, T.
European Journal of Human Genetics 22
(4): 480-485.
April 2014
Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling.
van Noort, V., Schoelch, S., Iskar, M., Zeller, G., Ostertag, K., Schweitzer, C., Werner, K., Weitz, J., Koch, M. and Bork, P.
Cancer Research 74
(20): 5690-5699.
15 October 2014
Comparison of native high-resolution 3D and contrast-enhanced MR angiography for assessing the thoracic aorta.
von Knobelsdorff-Brenkenhoff, F., Gruettner, H., Trauzeddel, R.F., Greiser, A. and Schulz-Menger, J.
European Heart Journal - Cardiovascular Imaging 15
(6): 651-658.
June 2014
Blood flow characteristics in the ascending aorta after aortic valve replacement-a pilot study using 4D-flow MRI.
von Knobelsdorff-Brenkenhoff, F., Trauzeddel, R.F., Barker, A.J., Gruettner, H., Markl, M. and Schulz-Menger, J.
International Journal of Cardiology 170
(3): 426-433.
1 January 2014
Vitamin D antagonizes negative effects of preeclampsia on fetal endothelial colony forming cell number and function.
von Versen-Höynck, F., Brodowski, L., Dechend, R., Myerski, A.C. and Hubel, C.A.
PLoS ONE 9
(6): e98990.
3 June 2014
Paternal diet defines offspring chromatin state and intergenerational obesity.
Öst, A., Lempradl, A., Casas, E., Weigert, M., Tiko, T., Deniz, M., Pantano, L., Boenisch, U., Itskov, P.M., Stoeckius, M., Ruf, M., Rajewsky, N., Reuter, G., Iovino, N., Ribeiro, C., Alenius, M., Heyne, S., Vavouri, T. and Pospisilik, J.A.
Cell 159
(6): 1352-1364.
4 December 2014
Rosuvastatin can block pro-inflammatory actions of transgenic human CRP without reducing its circulating levels.
Šilhavý, J., Zídek, V., Landa, V., Šimáková, M., Mlejnek, P., Škop, V., Oliyarnyk, O., Kazdová, L., Mancini, M., Saar, K., Schulz, H., Hübner, N., Kurtz, T.W. and Pravenec, M.
Cardiovascular Therapeutics 32
(2): 59-65.
April 2014
Book Section
Transcriptome-wide identification of protein binding sites on RNA by PAR-CLIP (photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation).
Hoell, J.I., Hafner, M., Landthaler, M., Ascano, M., Farazi, T.A., Wardle, G., Nusbaum, J., Cekan, P., Khorshid, M., Burger, L., Zavolan, M. and Tuschl, T.
In:
Handbook of RNA Biochemistry: Second, Completely Revised and Enlarged Edition.
Wiley-VCH, Weinheim, 877-898.
ISBN 9783527327645
2014
Whole grain and dietary fiber intake and risk of prostate cancer.
Nimptsch, K.
In:
Wheat and rice in disease prevention and health : benefits, risks and mechanisms of whole grains in health promotion.
Elsevier, Burlington, 113-120.
ISBN 978-0-12-401716-0
2014
Redundant human omentum fat: A leap towards regenerative medicine.
lndumathi, S., Harikrishnan, R. and Dhanasekaran, M.
In:
Regenerative Medicine.
Springer, 125-133.
ISBN 978-1-4471-6541-5
2014
Subcutaneous adipose tissue-derived stem cells: advancement and applications in regenerative medicine.
lndumathi, S., Mishra, R., Harikrishnan, R. and Dhanasekaran, M.
In:
Regenerative Medicine.
Springer, 91-112.
ISBN 978-1-4471-6541-5
2014
Conference or Workshop Item
Can active perception generate bistability? Heterogeneous collective dynamics and vascular patterning.
Bentley, K., Harrington, K.I. and Regan, E.
In: 14th International Conference on the Synthesis and Simulation of Living Systems (ALIFE 2014), 30 Jul - 02 Aug 2014, Manhattan, New York, USA.
July 2014
Modelling nonlinear chemical oscillators with inhibitory coupling.
Gold, J., Wang, A., Girabawe, C., Harrington, K. and Fraden, S.
In: 2014 40th Annual Northeast Bioengineering Conference (NEBEC), 25-27 Apr 2014, Boston, MA, USA.
4 December 2014
Feedback control of evolving swarms.
Gold, J., Wang, A. and Harrington, K.I.
In: 14th International Conference on the Synthesis and Simulation of Living Systems (ALIFE 2014), 30 Jul - 02 Aug 2014, Manhattan, New York, USA.
July 2014
Robot coverage control by evolved neuromodulation.
Harrington, K.I., Awa, E., Cussat-Blanc, S. and Pollack, J.
In: 2013 International Joint Conference on Neural Networks (IJCNN 2013), 4-9 Aug 2013, Dallas, TX, USA.
9 January 2014
Coevolution in hide and seek: camouflage and vision.
Harrington, K.I., Freeman, J. and Pollack, J.
In: 14th International Conference on the Synthesis and Simulation of Living Systems (ALIFE 2014), 30 Jul - 02 Aug 2014, Manhattan, New York, USA.
July 2014
The resistance of swarm ecosystem under environmental variation.
Lowell, J., Harrington, K. and Pollack, J.
In: 14th International Conference on the Synthesis and Simulation of Living Systems (ALIFE 2014), 30 Jul - 02 Aug 2014, Manhattan, New York, USA.
July 2014
Book
Neurotrophic factors.
Lewin, G.R. and Carter, B.D., eds.
Handbook of Experimental Pharmacology, 220
.
Springer, Berlin [u.a.].
ISBN 978-3-642-45105-8
2014
Review
When time stands still: an integrative review on the role of chronodisruption in posttraumatic stress disorder.
Agorastos, A., Kellner, M., Baker, D.G. and Otte, C.
Current Opinion in Psychiatry 27
(5): 385-392.
September 2014
Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system.
Amm, I., Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1843
(1): 182-196.
January 2014
Mas and its related G protein-coupled receptors, Mrgprs.
Bader, M., Alenina, N., Andrade-Navarro, M.A. and Santos, R.A.
Pharmacological Reviews 66
(4): 1080-1105.
October 2014
Structure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins.
Birol, M. and Echalier, A.
Current Protein & Peptide Science 15
(5): 504-517.
2014
Optimal management of multiple sclerosis during pregnancy: current perspectives.
Borisow, N., Paul, F. and Doerr, J.
Degenerative Neurological and Neuromuscular Disease 4
: 111-120.
5 August 2014
New avenues for genetics guided therapeutic approaches in AML.
Bullinger, L.
Acta Haematologica Polonica 45
(4): 322-329.
1 October 2014
Glimpse into Hox and tale regulation of cell differentiation and reprogramming.
Cerdá-Esteban, N. and Spagnoli, F.M.
Developmental Dynamics 243
(1): 76-87.
January 2014
BAR domain scaffolds in dynamin-mediated membrane fission.
Daumke, O., Roux, A. and Haucke, V.
Cell 156
(5): 882-892.
27 February 2014
Recent technological updates and clinical applications of induced pluripotent stem cells.
Diecke, S., Jung, S.M., Lee, J. and Ju, J.H.
Korean Journal of Internal Medicine 29
(5): 547-57.
September 2014
Tissue macrophage identity and self-renewal.
Gentek, R., Molawi, K. and Sieweke, M.H.
Immunological Reviews 262
(1): 56-73.
November 2014
CNS macrophages and peripheral myeloid cells in brain tumours.
Glass, R. and Synowitz, M.
Acta Neuropathologica 128
(3): 347-362.
September 2014
Modules, networks and systems medicine for understanding disease and aiding diagnosis.
Gustafsson, M., Nestor, C.E., Zhang, H., Barabási, A.L., Baranzini, S., Brunak, S., Chung, K.F., Federoff, H.J., Gavin, A.C., Meehan, R.R., Picotti, P., Pujana, M.À., Rajewsky, N., Smith, K.G.C., Sterk, P.J., Villoslada, P. and Benson, M.
Genome Medicine 6
(10): 82.
17 October 2014
The IκB kinase complex in NF-κB regulation and beyond.
Hinz, M. and Scheidereit, C.
EMBO Reports 15
(1): 46-61.
1 January 2014
Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib.
Huelsmann, H.J., Rolff, J., Bender, C., Jarahian, M., Korf, U., Herwig, R., Froehlich, H., Thomas, M., Merk, J., Fichtner, I., Sueltmann, H. and Kuner, R.
Lung Cancer 86
(2): 151-157.
November 2014
Macrophages in homeostatic immune function.
Jantsch, J., Binger, K.J., Müller, D.N. and Titze, J.
Frontiers in Physiology 5
: 146.
May 2014
Neuromyelitis optica: clinical features, immunopathogenesis and treatment.
Jarius, S., Wildemann, B. and Paul, F.
Clinical and Experimental Immunology 176
(2): 149-164.
May 2014
NF-κB in cellular senescence and cancer treatment.
Jing, H. and Lee, S.
Molecules and Cells 37
(3): 189-195.
31 March 2014
Every cell is special: genome-wide studies add a new dimension to single-cell biology.
Junker, J.P. and van Oudenaarden, A.
Cell 157
(1): 8-11.
27 March 2014
Ultrahochfeld-MRT im Kontext neurologischer Erkrankungen [Ultrahigh field MRI in context of neurological diseases].
Kuchling, J., Sinnecker, T., Bozin, I., Dörr, J., Madai, V.I., Sobesky, J., Niendorf, T., Paul, F. and Wuerfel, J.
Nervenarzt 85
(4): 445-458.
April 2014
In-vivo-Magnetresonanzmikroskopie des humanen Auges [In vivo MR microscopy of the human eye].
Langner, S., Krueger, P.C., Lindner, T., Niendorf, T. and Stachs, O.
Klinische Monatsblaetter fuer Augenheilkunde 231
(10): 1016-1022.
October 2014
Pro-neurotrophins, sortilin, and nociception.
Lewin, G.R. and Nykjaer, A.
European Journal of Neuroscience 39
(3): 363-374.
February 2014
Long non-coding RNA in health and disease.
Maass, P.G., Luft, F.C. and Bähring, S.
Journal of Molecular Medicine 92
(4): 337-346.
April 2014
Role of "western diet" in inflammatory autoimmune diseases.
Manzel, A., Muller, D.N., Hafler, D.A., Erdman, S.E., Linker, R.A. and Kleinewietfeld, M.
Current Allergy and Asthma Reports 14
(1): 404.
January 2014
Presynaptic mechanisms of neuronal plasticity and their role in epilepsy.
Meier, J.C., Semtner, M., Winkelmann, A. and Wolfart, J.
Frontiers in Cellular Neuroscience 8
: 164.
17 June 2014
Ophthalmologische Bildgebung mit Ultrahochfeld-Magnetresonanztomografie: technische Innovationen und wegweisende Anwendungen [Ophthalmological imaging with ultrahigh field magnetic resonance tomography: technical innovations and frontier applications].
Niendorf, T., Paul, K., Graessl, A., Els, A., Pohlmann, A., Rieger, J., Lindner, T., Krueger, P.C., Hadlich, S., Langner, S. and Stachs, O.
Klinische Monatsblaetter fuer Augenheilkunde 231
(12): 1187-1195.
December 2014
Adipositas und Krebs [Obesity and risk of cancer].
Nimptsch, K. and Pischon, T.
Adipositas 8
(3): 151-156.
2014
Depression and cognitive dysfunction: clinical relevance and therapeutic implications [Depression und kognitive Dysfunktion: klinische Relevanz und therapeutische Implikationen].
Otte, C.
Psychopharmakotherapie 21
(2): 40-49.
March 2014
The investigation of acute optic neuritis: a review and proposed protocol.
Petzold, A., Wattjes, M.P., Costello, F., Flores-Rivera, J., Fraser, C.L., Fujihara, K., Leavitt, J., Marignier, R., Paul, F., Schippling, S., Sindic, C., Villoslada, P., Weinshenker, B. and Plant, G.T.
Nature Reviews Neurology 10
(8): 447-458.
August 2014
Pulsed stable isotope-resolved metabolomic studies of cancer cells.
Pietzke, M. and Kempa, S.
Methods in Enzymology 543
: 179-198.
9 June 2014
Physical mechanisms behind the large scale features of chromatin organization.
Pombo, A. and Nicodemi, M.
Transcription 5
(2): e28447.
April 2014
Autophagy in the immune system.
Puleston, D.J. and Simon, A.K.
Immunology 141
(1): 1-8.
January 2014
(Pro)renin receptor and V-ATPase: from Drosophila to humans.
Rousselle, A., Sihn, G., Rotteveel, M. and Bader, M.
Clinical Science 126
(8): 529-536.
1 April 2014
Amorfrutins: a promising class of natural products that are beneficial to health.
Sauer, S.
ChemBioChem 15
(9): 1231-1238.
16 June 2014
Physical activity in the prevention of peripheral artery disease in the elderly.
Schiattarella, G.G., Perrino, C., Magliulo, F., Carbone, A., Bruno, A.G., De Paulis, M., Sorropago, A., Corrado, R.V., Bottino, R., Menafra, G., Abete, R., Toscano, E., Giugliano, G., Trimarco, B. and Esposito, G.
Frontiers in Physiology 5
: 12.
3 March 2014
Metabolic actions of natriuretic peptides and therapeutic potential in the metabolic syndrome.
Schlueter, N., de Sterke, A., Willmes, D.M., Spranger, J., Jordan, J. and Birkenfeld, A.L.
Pharmacology & Therapeutics 144
(1): 12-27.
October 2014
Apolipoprotein E receptor pathways in Alzheimer disease.
Schmidt, V., Carlo, A.S. and Willnow, T.E.
Wiley Interdisciplinary Reviews Systems Biology and Medicine 6
(3): 255-270.
May 2014
The IgCAMs CAR, BT-IgSF, and CLMP: structure, function, and diseases.
Schreiber, J., Langhorst, H., Jüttner, R. and Rathjen, F.G.
Advances in Neurobiology 8
: 21-45.
October 2014
Expression profiling of leukemia patients: key lessons and future directions.
Shivarov, V. and Bullinger, L.
Experimental Hematology 42
(8): 651-60.
August 2014
PAR-CLIP (photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of RNA-binding proteins.
Spitzer, J., Hafner, M., Landthaler, M., Ascano, M., Farazi, T., Wardle, G., Nusbaum, J., Khorshid, M., Burger, L., Zavolan, M. and Tuschl, T.
Methods in Enzymology 539
: 113-161.
25 February 2014
Generation of memory B cells inside and outside germinal centers.
Takemori, T., Kaji, T., Takahashi, Y., Shimoda, M. and Rajewsky, K.
European Journal of Immunology 44
(5): 1258-1264.
May 2014
Calcium-activated potassium channels in ischemia reperfusion: a brief update.
Tano, J.Y. and Gollasch, M.
Frontiers in Physiology 5
: 381.
October 2014
Spooky sodium balance.
Titze, J., Dahlmann, A., Lerchl, K., Kopp, C., Rakova, N., Schröder, A. and Luft, F.C.
Kidney International 85
(4): 759-767.
9 April 2014
Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS).
Trebst, C., Jarius, S., Berthele, A., Paul, F., Schippling, S., Wildemann, B., Borisow, N., Kleiter, I., Aktas, O. and Kümpfel, T.
Journal of Neurology 261
(1): 1-16.
January 2014
Spontaneous self-assembly of pathogenic huntingtin exon 1 protein into amyloid structures.
Trepte, P., Strempel, N. and Wanker, E.E.
Essays in Biochemistry 56
(1): 167-180.
18 August 2014
Sleep disorders in multiple sclerosis and their relationship to fatigue.
Veauthier, C. and Paul, F.
Sleep Medicine 15
(1): 5-14.
January 2014
Tissue guidance without filopodia.
Wacker, A., Gerhardt, H. and Phng, L.K.
Communicative & Integrative Biology 7
(1): e28820.
9 April 2014
Agonistic autoantibodies directed against G-protein-coupled receptors and their relationship to cardiovascular diseases.
Wallukat, G. and Schimke, I.
Seminars in Immunopathology 36
(3): 351-363.
May 2014
T2-mapping - clinical experience.
Wassmuth, R. and Schulz-Menger, J.
Current Cardiovascular Imaging Reports 7
(2): 9251.
7 January 2014
The regulatory potential of upstream open reading frames in eukaryotic gene expression.
Wethmar, K.
Wiley Interdisciplinary Reviews: RNA 5
(6): 765-768.
November 2014
Targeting the ubiquitin-proteasome system in atherosclerosis: status quo, challenges, and perspectives.
Wilck, N. and Ludwig, A.
Antioxidants & Redox Signaling 21
(17): 2344-2363.
24 November 2014
Atomistic Monte Carlo simulation of lipid membranes.
Wuestner, D. and Sklenar, H.
International Journal of Molecular Sciences 15
(2): 1767-803.
24 January 2014
Cardiovascular magnetic resonance in adults with previous cardiovascular surgery.
von Knobelsdorff-Brenkenhoff, F., Trauzeddel, R.F. and Schulz-Menger, J.
European Heart Journal - Cardiovascular Imaging 15
(3): 235-248.
March 2014
Letter
Skepticism is unjustified.
Abholz, H.H., Egidi, G., Mueller, U.A. and Spranger, J.
Deutsches Aerzteblatt International 111
(25): 433.
20 June 2014
Retinal segmentation to demonstrate hyperplasia in ataxia of charlevoix-saguenay: critique on study methodology and results.
Albrecht, P., Balk, L., Oberwahrenbrock, T., Petzold, A. and Paul, F.
Investigative Ophthalmology & Visual Science 55
(8): 4728.
4 August 2014
Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A.
Auer, F., Rueschendorf, F., Gombert, M., Husemann, P., Ginzel, S., Izraeli, S., Harit, M., Weintraub, M., Weinstein, O.Y., Lerer, I., Stepensky, P., Borkhardt, A. and Hauer, J.
Leukemia 28
(5): 1136-1138.
May 2014
Reply to: Photoreceptor layer thinning in Parkinsonian syndromes.
Brandt, A.U., Paul, F. and Saidha, S.
Movement Disorders 29
(9): 1222-1223.
August 2014
Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.
Cui, Y., Niziolek, P.J., MacDonald, B.T., Alenina, N., Matthes, S., Jacobsen, C.M., Conlon, R.A., Brommage, R., Powell, D.R., He, X., Bader, M., Williams, B.O., Warman, M.L. and Robling, A.G.
Nature Medicine 20
(11): 1229-1230.
6 November 2014
Human granulocytic anaplasmosis acquired in Scotland, 2013.
Hagedorn, P., Imhoff, M., Fischer, C., Domingo, C. and Niedrig, M.
Emerging Infectious Diseases 20
(6): 1079-1081.
June 2014
NF-κB activity is required for anagen maintenance in human hair follicles in vitro.
Kloepper, J.E., Ernst, N., Krieger, K., Bodo, E., Biro, T., Haslam, I.S., Schmidt-Ullrich, R. and Paus, R.
Journal of Investigative Dermatology 134
(7): 2036-2038.
11 February 2014
Dry roasting enhances peanut-induced allergic sensitization across mucosal and cutaneous routes in mice.
Moghaddam, A.E., Hillson, W.R., Noti, M., Gartlan, K.H., Johnson, S., Thomas, B., Artis, D. and Sattentau, Q.J.
Journal of Allergy and Clinical Immunology 134
(6): 1453-1456.
December 2014
A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.
Pieper, K., Rizzi, M., Speletas, M., Smulski, C.R., Sic, H., Kraus, H., Salzer, U., Fiala, G.J., Schamel, W.W., Lougaris, V., Plebani, A., Hammarstrom, L., Recher, M., Germenis, A.E., Grimbacher, B., Warnatz, K., Rolink, A.G., Schneider, P., Notarangelo, L.D. and Eibel, H.
Journal of Allergy and Clinical Immunology 133
(4): 1222-1225.
April 2014
The pitfalls of managing thrombosis of an Absorb(TM)-treated bifurcation.
Schiattarella, G.G., Magliulo, F., D'Alise, G., Mannacio, V., Ilardi, F., Trimarco, B., Esposito, G. and Cirillo, P.
International Journal of Cardiology 174
(3): e93-e95.
1 July 2014
Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.
Scholtens, S., Postma, D.S., Moffatt, M.F., Panasevich, S., Granell, R., Henderson, A.J., Melen, E., Nyberg, F., Pershagen, G., Jarvis, D., Ramasamy, A., Wjst, M., Svanes, C., Bouzigon, E., Demenais, F., Kauffmann, F., Siroux, V., von Mutius, E., Ege, M.J., Braun-Fahrlaender, C., Genuneit, J., Brunekreef, B., Smit, H.A., Wijga, A.H., Kerkhof, M., Curjuric, I., Imboden, M., Thun, G.A., Probst-Hensch, N., Freidin, M.B., Bragina, E.I., Deev, I.A., Puzyrev, V.P., Daley, D., Park, J., Becker, A., Chan-Yeung, M., Kozyrskyj, A.L., Pare, P., Marenholz, I., Lau, S., Keil, T., Lee, Y.A., Kabesch, M., Wijmenga, C., Franke, L., Nolte, I.M., Vonk, J., Kumar, A., Farrall, M., Cookson, W.O.C.M., Strachan, D.P., Koppelman, G.H. and Boezen, H.M.
Journal of Allergy and Clinical Immunology 133
(3): 885-888.
March 2014
Novel γ-sarcoglycan-mutation affects cardiac function and N-terminal dystrophin expression.
Schroeder, N.W.J., Grieben, U., Prokop, S., Dekomien, G., Epplen, J.T., Heppner, F.L., Goebel, H.H. and Stenzel, W.
Muscle & Nerve 49
(1): 144-145.
January 2014
Combined immunodeficiency develops with age in immunodeficiency-centromeric instability-facial anomalies syndrome 2 (ICF2).
von Bernuth, H., Ravindran, E., Du, H., Froehler, S., Strehl, K., Kraemer, N., Issa-Jahns, L., Amulic, B., Ninnemann, O., Xiao, M.S., Eirich, K., Koelsch, U., Hauptmann, K., John, R., Schindler, D., Wahn, V., Chen, W. and Kaindl, A.M.
Orphanet Journal of Rare Diseases 9
(1): 116.
21 October 2014
Editorial
Stem cell epigenetics: looking forward.
Benitah, S.A., Bracken, A., Dou, Y., Huangfu, D., Ivanova, N., Koseki, H., Laurent, L., Lim, D.A., Meshorer, E., Pombo, A., Sander, M. and Xu, G.L.
Cell Stem Cell 14
(6): 706-709.
5 June 2014
Mouse models of human cancer.
Böck, B.C., Stein, U., Schmitt, C.A. and Augustin, H.G.
Cancer Research 74
(17): 4671-4675.
1 September 2014
Comments on "Human dominant disease genes are enriched in paralogs originating from whole genome duplication".
Chen, W.H., Zhao, X.M., van Noort, V. and Bork, P.
PLoS Computational Biology 10
(7): e1003758.
31 July 2014
Sind ACE-Hemmer besser als Angiotensin-Rezeptor-Blocker fuer Diabetiker? Ueberraschende Ergebnisse aus einer großen Metaanalyse [Are ACE inhibitors better than angiotensin receptor blockers for diabetics? Surprising results from a large-scale meta-analysis].
Derer, W. and Dechend, R.
Diabetes, Stoffwechsel und Herz 23
(3): 174-175.
20 June 2014
Simplifying cardiovascular magnetic resonance pulse sequence terminology.
Friedrich, M.G., Bucciarelli-Ducci, C., White, J.A., Plein, S., Moon, J.C., Almeida, A.G., Kramer, C.M., Neubauer, S., Pennell, D.J., Petersen, S.E., Kwong, R.Y., Ferrari, V.A., Schulz-Menger, J., Sakuma, H., Schelbert, E.B., Larose, É., Eitel, I., Carbone, I., Taylor, A.J., Young, A., de Roos, A. and Nagel, E.
Journal of Cardiovascular Magnetic Resonance 16
(1): 3960.
31 December 2014
Lymphotoxin-α keeps the gate open for T-cell infiltration in cHL.
Höpken, U.E.
Blood 124
(19): 2897-2898.
6 November 2014
Long-term structured follow-up is essential after curative cancer treatment.
Keilholz, U., Pezzutto, A., Budach, V. and Eggert, A.
Deutsches Aerzteblatt International 111
(1-2): 1-2.
6 January 2014
With complements from ANCA mice.
Kettritz, R.
Journal of the American Society of Nephrology 25
(2): 207-209.
February 2014
New insights into the cell lineage of pancreatic ductal adenocarcinoma: evidence for tumor stem cells in premalignant lesions?
Kopp, J.L. and Sander, M.
Gastroenterology 146
(1): 24-6.
January 2014
Editing and investigating genomes with TALE and CRISPR/Cas systems: Genome engineering across species using TALENs.
Kuehn, R. and Wefers, B.
Methods 69
(1): 1.
15 August 2014
Semaphorin-3A is a repulsive but attractive renal guidance cue to therapy.
Luft, F.C.
Journal of Molecular Medicine 92
(12): 1225-1227.
December 2014
Mesenchymal stem cells seem too good to believe!
Luft, F.C.
Journal of Molecular Medicine 92
(11): 1117-1118.
November 2014
Aberrant transcriptional regulation could explain phenotypic variability in autosomal recessive polycystic kidney disease.
Luft, F.C.
Journal of Molecular Medicine 92
(10): 1011-1014.
October 2014
Aortas reveal the myth of male privilege.
Luft, F.C.
Journal of Molecular Medicine 92
(9): 901-903.
September 2014
ACE in the hole.
Luft, F.C.
Journal of Molecular Medicine 92
(8): 793-795.
August 2014
Preparation for hypertension specialists : genomics reveals the pathogenesis of hypertension.
Luft, F.C.
Journal of the American Society of Hypertension 8
(8): 607-611.
August 2014
Sodium shows no mercy on the nanomechanics of endothelial cells.
Luft, F.C.
Hypertension 64
(2): 231-232.
August 2014
GABA the Hutt.
Luft, F.C.
Journal of Molecular Medicine 92
(6): 551-553.
June 2014
Acid sphingomyelinase, autophagy, and atherosclerosis.
Luft, F.C.
Journal of Molecular Medicine 92
(5): 429-431.
May 2014
SYMPLICITY: not all that simple.
Luft, F.C.
Kidney International 85
(5): 999-1001.
May 2014
Are you certain about SIRT?
Luft, F.C.
Journal of Molecular Medicine 92
(4): 305-306.
April 2014
Soluble fms-like tyrosine kinase-1 and atherosclerosis in chronic kidney disease.
Luft, F.C.
Kidney International 85
(2): 238-240.
February 2014
ERα on the cell membrane helps the heart.
Luft, F.C.
Journal of Molecular Medicine 92
(1): 1-3.
January 2014
Gunfight at O.K. CORAL.
Luft, F.C., Safak, E. and Dechend, R.
Journal of the American Society of Hypertension 8
(4): 276-280.
April 2014
Gene expression: degrade to derepress.
McShane, E. and Selbach, M.
EMBO Journal 33
(5): 407-408.
3 March 2014
Detailing intra-lesional venous lumen shrinking in multiple sclerosis investigated by sFLAIR MRI at 7-T.
Mueller, K., Kuchling, J., Doerr, J., Harms, L., Ruprecht, K., Niendorf, T., Wuerfel, J., Paul, F. and Sinnecker, T.
Journal of Neurology 261
(10): 2032-2036.
October 2014
Mixed messages: re-initiation factors regulate translation of animal mRNAs.
Obermayer, B. and Rajewsky, N.
Cell Research 24
(12): 1383-1384.
December 2014
Chronic cerebrospinal venous insufficiency in multiple sclerosis: the final curtain.
Paul, F. and Wattjes, M.P.
Lancet 383
(9912): 106-108.
11 January 2014
Keeping an eye on cortical States.
Poulet, J.F.A.
Neuron 84
(2): 246-248.
22 October 2014
Michael S. Neuberger 1953-2013.
Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 111
(8): 2862-2863.
25 February 2014
Micro-managing the pancreatic β cell.
Rathjen, T., Tattikota, S.G. and Poy, M.N.
Cell Cycle 13
(8): 1216-1217.
15 April 2014
Developmental biology: it takes muscle to make blood cells.
Sawamiphak, S. and Stainier, D.Y.R.
Nature 512
(7514): 257-258.
21 August 2014
tURn the lights on: mitochondrial transport-RNAs and cardiovascular disease.
Schiattarella, G.G., Trimarco, B., Perrino, C. and Esposito, G.
Journal of the American Heart Association 3
(1): e000757.
27 January 2014
The Ebf1 knockout mouse and glomerular maturation.
Schmidt-Ott, K.M.
Kidney International 85
(5): 1014-1016.
May 2014
Retrograde signaling causes excitement.
Schmitz, D., Breustedt, J. and Gundlfinger, A.
Neuron 81
(4): 717-719.
19 February 2014
Diagnostic accuracy of CMR in biopsy-proven acute myocarditis.
Schulz-Menger, J.
JACC: Cardiovascular Imaging 7
(3): 264-266.
17 March 2014
Rsp5/Nedd4 clears cells of heat-damaged proteins.
Sommer, T., Weber, A. and Jarosch, E.
Nature Cell Biology 16
(12): 1130-1132.
1 December 2014
The ubiquitin-proteasome-system.
Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1843
(1): 1.
January 2014
Bone biology: vessels of rejuvenation.
le Noble, F. and le Noble, J.
Nature 507
(7492): 313-314.
20 March 2014
Comment
A mitochondrial strategy for safeguarding the reprogrammed genome.
Prigione, A. and Adjaye, J.
Cell Regeneration 3
(1): 5.
29 March 2014
Preprint
LIMIX: genetic analysis of multiple traits.
Lippert, C., Casale, F.P., Rakitsch, B. and Stegle, O.
bioRxiv
: 003905.
22 May 2014
This list was generated on Sat Oct 12 10:03:26 2024 UTC.