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A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4(+) T cells and is defective in Crohn's disease patients.
Ahlers, J. and Mantei, A. and Lozza, L. and Stäber, M. and Heinrich, F. and Bacher, P. and Hohnstein, T. and Menzel, L. and Yüz, S.G. and Alvarez-Simon, D. and Bickenbach, A.R. and Weidinger, C. and Mockel-Tenbrinck, N. and Kühl, A.A. and Siegmund, B. and Maul, J. and Neumann, C. and Scheffold, A.
Mucosal Immunology 15 (3): 480-490. May 2022

Midwall fibrosis and cardiac mechanics: rigid body rotation is a novel marker of disease severity in pediatric primary dilated cardiomyopathy.
Al-Wakeel-Marquard, N. and Seidel, F. and Kühnisch, J. and Kuehne, T. and Berger, F. and Messroghli, D.R. and Klaassen, S.
Frontiers in Cardiovascular Medicine 8 : 810005. 17 February 2022

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H. and Flórez, A.F. and Kreth, S. and Brückner, L.M. and Yildiz, U. and Gartlgruber, M. and Odoni, D.I. and Poschet, G. and Garbowicz, K. and Shao, C. and Klein, C. and Meier, J. and Zeisberger, P. and Nadler-Holly, M. and Ziehm, M. and Paul, F. and Burhenne, J. and Bell, E. and Shaikhkarami, M. and Würth, R. and Stainczyk, S.A. and Wecht, E.M. and Kreth, J. and Büttner, M. and Ishaque, N. and Schlesner, M. and Nicke, B. and Stresemann, C. and Llamazares-Prada, M. and Reiling, J.H. and Fischer, M. and Amit, I. and Selbach, M. and Herrmann, C. and Wölfl, S. and Henrich, K.O. and Höfer, T. and Trumpp, A. and Westermann, F.
Nature Cancer 3 (4): 471-485. 28 April 2022

Different impact of gadopentetate and gadobutrol on inflammation-promoted retention and toxicity of gadolinium within the mouse brain.
Anderhalten, L. and Silva, R.V. and Morr, A. and Wang, S. and Smorodchenko, A. and Saatz, J. and Traub, H. and Mueller, S. and Boehm-Sturm, P. and Rodriguez-Sillke, Y. and Kunkel, D. and Hahndorf, J. and Paul, F. and Taupitz, M. and Sack, I. and Infante-Duarte, C.
Investigative Radiology 22 April 2022 (In Press)

The role of respiratory microbiota in the protection against viral diseases: respiratory commensal bacteria as next-generation probiotics for COVID-19.
Andrade, B.G.N. and Cuadrat, R.R.C. and Tonetti, F.R. and Kitazawa, H. and Villena, J.
Bioscience of Microbiota, Food and Health 29 March 2022 (In Press)

Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming.
Anh, L.P.H. and Nishimura, K. and Kuno, A. and Nguyen, T.L. and Kato, T. and Ohtaka, M. and Nakanishi, M. and Sugihara, E. and Sato, T.A. and Hayashi, Y. and Fukuda, A. and Hisatake, K.
Stem Cells 40 (4): 397-410. 29 April 2022

Prognostic value of stress cardiac magnetic resonance in patients with known coronary artery disease.
Antiochos, P. and Ge, Y. and Heydari, B. and Steel, K. and Bingham, S. and Abdullah, S.M. and Mikolich, J.R. and Arai, A.E. and Bandettini, W.P. and Patel, A.R. and Farzaneh-Far, A. and Heitner, J.F. and Shenoy, C. and Leung, S.W. and Gonzalez, J.A. and Shah, D.J. and Raman, S.V. and Ferrari, V.A. and Schulz-Menger, J. and Stuber, M. and Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 15 (1): 60-71. January 2022

Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling.
Anton, S.E. and Kayser, C. and Maiellaro, I. and Nemec, K. and Möller, J. and Koschinski, A. and Zaccolo, M. and Annibale, P. and Falcke, M. and Lohse, M.J. and Bock, A.
Cell 185 (7): 1130-1142.e11. 31 March 2022

Carbon-mixed dental cement for fixing fiber optic ferrules prevents visually triggered locomotive enhancement in mice upon optogenetic stimulation.
Araragi, N. and Alenina, N. and Bader, M.
Heliyon 8 (1): e08692. January 2022

LABKIT: labeling and segmentation toolkit for big image data.
Arzt, M. and Deschamps, J. and Schmied, C. and Pietzsch, T. and Schmidt, D. and Tomancak, P. and Haase, R. and Jug, F.
Frontiers in Computer Science 4 : 777728. 10 February 2022

De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway.
Asif, M. and Kaygusuz, E. and Shinawi, M. and Nickelsen, A. and Hsieh, T.C. and Wagle, P. and Budde, B. and Hochscherf, J. and Abdullah, U. and Höning, S. and Nienberg, C. and Lindenblatt, D. and Noegel, A.A. and Altmüller, J. and Thiele, H. and Motameny, S. and Fleischer, N. and Segal, I. and Pais, L. and Tinschert, S. and Samra, N.G. and Savatt, J.M. and Rudy, N.L. and De Luca, C. and Fortugno, P. and White, S.M. and Krawitz, P. and Hurst, A.C.E. and Niefind, K. and Jose, J. and Brancati, F. and Nürnberg, P. and Hussain, M.S.
Human Genetics and Genomics Advances 3 (3): 100111. 14 July 2022

A novel missense variant of SCN4A co-segregates with congenital essential tremor in a consanguineous Kurdish family.
Asif, M. and Mocanu, I.D. and Abdullah, U. and Höhne, W. and Altmüller, J. and Makhdoom, E.U.H. and Thiele, H. and Baig, S.M. and Nürnberg, P. and Graul-Neumann, L. and Hussain, M.S.
American Journal of Medical Genetics A 188 (4): 1251-1258. April 2022

Impaired motion perception is associated with functional and structural visual pathway damage in multiple sclerosis and neuromyelitis optica spectrum disorders.
Ayadi, N. and Oertel, F.C. and Asseyer, S. and Rust, R. and Duchow, A. and Kuchling, J. and Bellmann-Strobl, J. and Ruprecht, K. and Klistorner, A. and Brandt, A.U. and Paul, F. and Zimmermann, H.G.
Multiple Sclerosis Journal 28 (5): 757-767. April 2022

Anatomical and functional visual network patterns in progressive multiple sclerosis.
Backner, Y. and Zamir, S. and Petrou, P. and Paul, F. and Karussis, D. and Levin, N.
Human Brain Mapping 43 (5): 1590-1597. 1 April 2022

Microglia form satellites with different neuronal subtypes in the adult murine central nervous system.
Bakina, O. and Kettenmann, H. and Nolte, C.
Journal of Neuroscience Research 100 (4): 1105-1122. April 2022

Unraveling the hidden temporal range of fast β(2)-adrenergic receptor mobility by time-resolved fluorescence.
Balakrishnan, A. and Hemmen, K. and Choudhury, S. and Krohn, J.H. and Jansen, K. and Friedrich, M. and Beliu, G. and Sauer, M. and Lohse, M.J. and Heinze, K.G.
Communications Biology 5 (1): 176. 28 February 2022

Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S. and Andreani, M. and Goncalves Andrade, J. and Saha, T. and Sundaravinayagam, D. and Garzón, J. and Zhang, W. and Popp, O. and Hiraga, S. and Rahjouei, A. and Rosen, D.B. and Mertins, P. and Chait, B.T. and Donaldson, A.D. and Di Virgilio, M.
eLife 11 : e75047. 13 April 2022

Aurora kinase A is involved in controlling the localization of aquaporin-2 in renal principal cells.
Baltzer, S. and Bulatov, T. and Schmied, C. and Krämer, A. and Berger, B.T. and Oder, A. and Walker-Gray, R. and Kuschke, C. and Zühlke, K. and Eichhorst, J. and Lehmann, M. and Knapp, S. and Weston, J. and von Kries, J.P. and Süssmuth, R.D. and Klussmann, E.
International Journal of Molecular Sciences 23 (2): 763. 11 January 2022

Sexual dimorphism in extracellular matrix composition and viscoelasticity of the healthy and inflamed mouse brain.
Batzdorf, C.S. and Morr, A.S. and Bertalan, G. and Sack, I. and Silva, R.V. and Infante-Duarte, C.
Biology 11 (2): 230. 31 January 2022

Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 72 (5): 175-184. May 2022

AQUA mutant protein quantification of endomyocardial biopsy-sized samples from a patient with hypertrophic cardiomyopathy.
Becker, E. and Francino, A. and Pich, A. and Perrot, A. and Kraft, T. and Radocaj, A.
Frontiers in Cardiovascular Medicine 9 : 816330. 21 February 2022

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
Belda, E. and Voland, L. and Tremaroli, V. and Falony, G. and Adriouch, S. and Assmann, K.E. and Prifiti, E. and Aron-Wisnewsky, J. and Debédat, J. and Le Roy, T. and Nielsen, T. and Amouyal, C. and André, S. and Andreelli, F. and Blüher, M. and Chakaroun, R. and Chilloux, J. and Coelho, L.P. and Dao, M.C. and Das, P. and Fellahi, S. and Forslund, S. and Galleron, N. and Hansen, T.H. and Holmes, B. and Ji, B. and Krogh Pedersen, H. and Le, P. and Le Chatelier, E. and Lewinter, C. and Mannerås-Holm, L. and Marquet, F. and Myridakis, A. and Pelloux, V. and Pons, N. and Quinquis, B. and Rouault, C. and Roume, H. and Salem, J.E. and Sokolovska, N. and Søndertoft, N.B. and Touch, S. and Vieira-Silva, S. and Galan, P. and Holst, J. and Gøtze, J.P. and Køber, L. and Vestergaard, H. and Hansen, T. and Hercberg, S. and Oppert, J.M. and Nielsen, J. and Letunic, I. and Dumas, M.E. and Stumvoll, M. and Pedersen, O.B. and Bork, P. and Ehrlich, S.D. and Zucker, J.D. and Bäckhed, F. and Raes, J. and Clément, K.
Gut 11 January 2022 (In Press)

Electrocardiographic changes during initiation of lithium augmentation of antidepressant pharmacotherapy.
Berger, M. and Kermer, J. and Behr, J. and Schulz-Menger, J. and Bilal, S. and Osterland, S.L. and O'Malley, G. and Bschor, T. and Schlattmann, P. and Stamm, T. and Steinacher, B. and de Millas, W. and Richter, C. and Heinz, A. and Adli, M. and Buspavanich, P. and Ricken, R.
Journal of Clinical Psychopharmacology 42 (1): 87-91. January 2022

The single-cell transcriptional landscape of lung carcinoid tumors.
Bischoff, P. and Trinks, A. and Wiederspahn, J. and Obermayer, B. and Pett, J.P. and Jurmeister, P. and Elsner, A. and Dziodzio, T. and Rückert, J.C. and Neudecker, J. and Falk, C. and Beule, D. and Sers, C. and Morkel, M. and Horst, D. and Klauschen, F. and Blüthgen, N.
International Journal of Cancer 150 (12): 2058-2071. 15 June 2022

Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R. and Dickinson, M. and Purtill, D. and Barba, P. and Santoro, A. and Hamad, N. and Kato, K. and Sureda, A. and Greil, R. and Thieblemont, C. and Morschhauser, F. and Janz, M. and Flinn, I. and Rabitsch, W. and Kwong, Y.L. and Kersten, M.J and Minnema, M.C. and Holte, H. and Chan, E.H.L. and Martinez-Lopez, J. and Müller, A.M.S. and Maziarz, R.T. and McGuirk, J.P. and Bachy, E. and Le Gouill, S. and Dreyling, M. and Harigae, H. and Bond, D. and Andreadis, C. and McSweeney, P. and Kharfan-Dabaja, M. and Newsome, S. and Degtyarev, E. and Awasthi, R. and Del Corral, C. and Andreola, G. and Masood, A. and Schuster, S.J. and Jäger, U. and Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386 (7): 629-639. 17 February 2022

Impact of dietary intervention on serum neurofilament light chain in multiple sclerosis.
Bock, M. and Steffen, F. and Zipp, F. and Bittner, S.
Neurology Neuroimmunology & Neuroinflammation 9 (1): e1102. January 2022

Lifelong effect of therapy in young patients with the cOL4A5 alport missense variant p.(Gly624Asp): a prospective cohort study.
Boeckhaus, J. and Hoefele, J. and Riedhammer, K.M. and Nagel, M. and Beck, B. and Choi, M. and Gollasch, M. and Bergmann, C. and Sonntag, J.E. and Troesch, V. and Stock, J. and Gross, O.
Nephrology Dialysis Transplantation : gfac006. 12 January 2022 (In Press)

Examination of the contributions of maternal/placental-derived galectin-1 to pregnancy outcome.
Borowski, S. and Freitag, N. and Urban, I. and Michel, G. and Barrientos, G. and Blois, S.M.
Methods in Molecular Biology 2442 : 603-619. 2022

Conditioning with fludarabine and treosulfan compared to FLAMSA-RIC in allogeneic stem cell transplantation for myeloid malignancies: a retrospective single-center analysis.
Braitsch, K. and Schwarz, A. and Koch, K. and Hubbuch, M. and Menzel, H. and Keller, U. and Götze, K.S. and Bassermann, F. and Herhaus, P. and Verbeek, M.
Annals of Hematology 101 (6): 1311-1319. June 2022

Central stress processing, T-cell responsivity to stress hormones, and disease severity in multiple sclerosis.
Brasanac, J. and Hetzer, S. and Asseyer, S. and Kuchling, J. and Bellmann-Strobl, J. and Ritter, K. and Gamradt, S. and Scheel, M. and Haynes, J.D. and Brandt, A.U. and Paul, F. and Gold, S.M. and Weygandt, M.
Brain Communications 4 (2): fcac086. 4 April 2022

Immune signature of multiple sclerosis-associated depression.
Brasanac, J. and Ramien, C. and Gamradt, S. and Tänzer, A. and Glau, L. and Ritter, K. and Patas, K. and Agorastos, A. and Wiedemann, K. and Demiralay, C. and Fischer, F. and Otte, C. and Bellmann-Strobl, J. and Friese, M.A. and Tolosa, E. and Paul, F. and Heesen, C. and Weygandt, M. and Gold, S.M.
Brain Behavior and Immunity 100 : 174-182. February 2022

Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways.
Braun, T. and Glass, M. and Wahnschaffe, L. and Otte, M. and Mayer, P. and Franitza, M. and Altmüller, J. and Hallek, M. and Hüttelmaier, S. and Schrader, A. and Herling, M.
Haematologica 107 (1): 187-200. January 2022

Noncanonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemia.
Braun, T. and Stachelscheid, J. and Bley, N. and Oberbeck, S. and Otte, M. and Müller, T.A. and Wahnschaffe, L. and Glaß, M. and Ommer, K. and Franitza, M. and Gathof, B. and Altmüller, J. and Hallek, M. and Auguin, D. and Hüttelmaier, S. and Schrader, A. and Herling, M.
Cancer Research 82 (9): 1818–1831. 1 May 2022

Claudin-10a deficiency shifts proximal tubular Cl(-) permeability to cation selectivity via claudin-2 redistribution.
Breiderhoff, T. and Himmerkus, N. and Meoli, L. and Fromm, A. and Sewerin, S. and Kriuchkova, N. and Nagel, O. and Ladilov, Y. and Krug, S. and Quintanova, C. and Stumpp, M. and Garbe-Schönberg, D. and Westernströer, U. and Merkel, C. and Brinkhus, M. and Altmüller, J. and Schweiger, M. and Mueller, D. and Mutig, K. and Morawski, M. and Halbritter, J. and Milatz, S. and Bleich, M. and Günzel, D.
Journal of the American Society of Nephrology 33 (4): 699-717. April 2022

The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L. and Morao, A.K. and Kim, J. and Jimenez, D.S. and Maryn, N. and Bikkasani, K. and Carrozza, M.J. and Albritton, S.E. and Kramer, M. and Street, L.A. and Cerimi, K. and Schumann, V.F. and Bahry, E. and Preibisch, S. and Woehler, A. and Ercan, S.
Journal of Cell Science 135 (2): jcs258818. January 2022

Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation.
Brunner, A.D. and Thielert, M. and Vasilopoulou, C. and Ammar, C. and Coscia, F. and Mund, A. and Hoerning, O.B. and Bache, N. and Apalategui, A. and Lubeck, M. and Richter, S. and Fischer, D.S. and Raether, O. and Park, M.A. and Meier, F. and Theis, F.J. and Mann, M.
Molecular Systems Biology 18 (3): e10798. 1 March 2022

The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.
Buffenstein, R. and Amoroso, V. and Andziak, B. and Avdieiev, S. and Azpurua, J. and Barker, A.J. and Bennett, N.C. and Brieño-Enríquez, M.A. and Bronner, G.N. and Coen, C. and Delaney, M.A. and Dengler-Crish, C.M. and Edrey, Y.H. and Faulkes, C.G. and Frankel, D. and Friedlander, G. and Gibney, P.A. and Gorbunova, V. and Hine, C. and Holmes, M.M. and Jarvis, J.U.M. and Kawamura, Y. and Kutsukake, N. and Kenyon, C. and Khaled, W.T. and Kikusui, T. and Kissil, J. and Lagestee, S. and Larson, J. and Lauer, A. and Lavrenchenko, L.A. and Lee, A. and Levitt, J.B. and Lewin, G.R. and Lewis Hardell, K.N. and Lin, T.D. and Mason, M.J. and McCloskey, D. and McMahon, M. and Miura, K. and Mogi, K. and Narayan, V. and O'Connor, T.P. and Okanoya, K. and O'Riain, M.J. and Park, T.J. and Place, N.J. and Podshivalova, K. and Pamenter, M.E. and Pyott, S.J. and Reznick, J. and Ruby, J.G. and Salmon, A.B. and Santos-Sacchi, J. and Sarko, D.K. and Seluanov, A. and Shepard, A. and Smith, M. and Storey, K.B. and Tian, X. and Vice, E.N. and Viltard, M. and Watarai, Ak. and Wywial, E. and Yamakawa, M. and Zemlemerova, E.D. and Zions, M. and Smith, E.S.J.
Biological Reviews 97 (1): 115-140. February 2022

The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression.
Bujanic, L. and Shevchuk, O. and von Kügelgen, N. and Kalinina, A. and Ludwik, K. and Koppstein, D. and Zerna, N. and Sickmann, A. and Chekulaeva, M.
RNA 28 (5): 766-779. May 2022

Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA interdisciplinary expert consensus.
Buske, C. and Dreyling, M. and Alvarez-Larrán, A. and Apperley, J. and Arcaini, L. and Besson, C. and Bullinger, L. and Corradini, P. and Della Porta, M.G. and Dimopoulos, M. and D’Sa, S. and Eich, H.T. and Foà, R. and Ghia, P. and Gomes da Silva, M. and Gribben, J. and Hajek, R. and Harrison, C. and Heuser, M. and Kiesewetter, B. and Kiladjian, J.J. and Kröger, N. and Moreau, P. and Passweg, J.R. and Peyvandi, F. and Rea, D. and Ribera, J.M. and Robak, T. and San-Miguel, J.F. and Santini, V. and Sanz, G. and Sonneveld, P. and von Lilienfeld-Toal, M. and Wendtner, C. and Pentheroudakis, G. and Passamonti, F.
ESMO Open 7 (2): 100403. April 2022

Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I. and Jaeschke, L. and Nimptsch, K. and Janke, J. and Herrmann, P. and Kobelt, D. and Kielstein, H. and Pischon, T. and Stein, U.
International Journal of Oncology 60 (2): 17. February 2022

Immune competence and spleen size scale with colony status in the naked mole-rat.
Bégay, V. and Cirovic, B. and Barker, A.J. and Klopffleisch, R. and Hart, D.W. and Bennett, N.C. and Lewin, G.R.
Open Biology 12 (4): 210292. 6 April 2022

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
Cabral-Marques, O. and Halpert, G. and Schimke, L.F. and Ostrinski, Y. and Vojdani, A. and Baiocchi, G.C. and Freire, P.P. and Filgueiras, I.S. and Zyskind, I. and Lattin, M.T. and Tran, F. and Schreiber, S. and Marques, A.H.C. and Plaça, D.R. and Fonseca, D.L.M. and Humrich, J.Y. and Müller, A. and Giil, L.M. and Graßhoff, H. and Schumann, A. and Hackel, A. and Junker, J. and Meyer, C. and Ochs, H.D. and Lavi, Y.B. and Scheibenbogen, C. and Dechend, R. and Jurisica, I. and Schulze-Forster, K. and Silverberg, J.I. and Amital, H. and Zimmerman, J. and Heidecke, H. and Rosenberg, A.Z. and Riemekasten, G. and Shoenfeld, Y.
Nature Communications 13 (1): 1220. 9 March 2022

AKAP18δ anchors and regulates CaMKII activity at phospholamban-SERCA2 and RYR.
Carlson, C.R. and Aronsen, J.M. and Bergan-Dahl, A. and Moutty, M.C. and Lunde, M. and Lunde, P.K. and Jarstadmarken, H. and Wanichawan, P. and Pereira, L. and Kolstad, T.R.S. and Dalhus, B. and Subramanian, H. and Hille, S. and Christensen, G. and Müller, O.J. and Nikolaev, V. and Bers, D.M. and Sjaastad, I. and Shen, X. and Louch, W.E. and Klussmann, E. and Sejersted, O.M.
Circulation Research 130 (1): 27-44. 7 January 2022

Seasonal variation in attacks of neuromyelitis optica spectrum disorders and multiple sclerosis: evaluation of 794 attacks from a nationwide registry in Argentina.
Carnero Contentti, E. and Lopez, P.A. and Pettinicchi, J.P. and Criniti, J. and Pappolla, A. and Miguez, J. and Patrucco, L. and Cristiano, E. and Liwacki, S. and Tkachuk, V. and Balbuena, M.E. and Vrech, C. and Deri, N. and Correale, J. and Marrodan, M. and Ysrraelit, M.C. and Leguizamon, F. and Luetic, G. and Menichini, M.L. and Tavolini, D. and Mainella, C. and Zanga, G. and Burgos, M. and Hryb, J. and Barboza, A. and Lazaro, L. and Alonso, R. and Fernández Liguori, N. and Nadur, D. and Chercoff, A. and Alonso Serena, M. and Caride, A. and Paul, F. and Rojas, J.I.
Multiple Sclerosis and Related Disorders 58 : 103466. February 2022

Association of maintenance intravenous immunoglobulin with prevention of relapse in adult myelin oligodendrocyte glycoprotein antibody-associated disease.
Chen, J.J. and Huda, S. and Hacohen, Y. and Levy, M. and Lotan, I. and Wilf-Yarkoni, A. and Stiebel-Kalish, H. and Hellmann, M.A. and Sotirchos, E.S. and Henderson, A.D. and Pittock, S.J. and Bhatti, M.T. and Eggenberger, E.R. and Di Nome, M. and Kim, H.J. and Kim, S.H. and Saiz, A. and Paul, F. and Dale, R.C. and Ramanathan, S. and Palace, J. and Camera, V. and Leite, M.I. and Lam, B.L. and Bennett, J.L. and Mariotto, S. and Hodge, D. and Audoin, B. and Maillart, E. and Deschamps, R. and Pique, J. and Flanagan, E.P. and Marignier, R.
JAMA Neurology 79 (5): 518-525. 1 May 2022

OCT retinal nerve fiber layer thickness differentiates acute optic neuritis from MOG antibody-associated disease and Multiple Sclerosis: RNFL thickening in acute optic neuritis from MOGAD vs MS.
Chen, J.J. and Sotirchos, E.S. and Henderson, A.D. and Vasileiou, E.S. and Flanagan, E.P. and Bhatti, M.T. and Jamali, S. and Eggenberger, E.R. and Dinome, M. and Frohman, L.P. and Arnold, A.C. and Bonelli, L. and Seleme, N. and Mejia-Vergara, A.J. and Moss, H.E. and Padungkiatsagul, T. and Stiebel-Kalish, H. and Lotan, I. and Hellmann, M.A. and Hodge, D. and Oertel, F.C. and Paul, F. and Saidha, S. and Calabresi, P.A. and Pittock, S.J.
Multiple Sclerosis and Related Disorders 58 : 103525. February 2022

Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F. and Hablesreiter, R. and Hoyer, K. and Hennch, C. and Maluck-Böttcher, A. and Segler, A. and Madadi, A. and Frick, M. and Bullinger, L. and Briest, F. and Damm, F.
Leukemia 36 (4): 1102-1110. April 2022

A novel complex genomic rearrangement affecting the KCNJ2 regulatory region causes a variant of Cooks syndrome.
Cinque, L. and Micale, L. and Manara, E. and Esposito, A. and Palumbo, O. and Chiariello, A.M. and Bianco, S. and Guerri, G. and Bertelli, M. and Giuffrida, M.G. and Bernardini, L. and Notarangelo, A. and Nicodemi, M. and Castori, M.
Human Genetics 141 (2): 217-227. February 2022

Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E. and Althoff, S. and Ruß, J. and Rosnev, S. and Butze, M. and Pühl, M. and Frentsch, M. and Bullinger, L. and Na, I.K.
International Journal of Molecular Sciences 23 (6): 3207. 16 March 2022

Towards the biogeography of prokaryotic genes.
Coelho, L.P. and Alves, R. and Del Río, Á.R. and Myers, P.N. and Cantalapiedra, C.P. and Giner-Lamia, J. and Schmidt, T.S. and Mende, D.R. and Orakov, A. and Letunic, I. and Hildebrand, F. and Van Rossum, T. and Forslund, S.K. and Khedkar, S. and Maistrenko, O.M. and Pan, S. and Jia, L. and Ferretti, P. and Sunagawa, S. and Zhao, X.M. and Nielsen, H.B. and Huerta-Cepas, J. and Bork, P.
Nature 601 (7892): 252-256. 13 January 2022

Efficient computational implementation of polymer physics models to explore chromatin structure.
Conte, M. and Esposito, A. and Fiorillo, L. and Campanile, R. and Annunziatella, C. and Corrado, A. and Chiariello, M.G. and Bianco, S. and Chiariello, A.M.
International Journal of Parallel, Emergent and Distributed Systems 37 (1): 91-102. January 2022

A polymer physics model to dissect genome organization in healthy and pathological phenotypes.
Conte, M. and Fiorillo, L. and Bianco, S. and Chiariello, A.M. and Esposito, A. and Musella, F. and Flora, F. and Abraham, A. and Nicodemi, M.
Methods in Molecular Biology 2301 : 307-316. 2022

Hypothalamic galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop.
Corradi, L. and Bruzzone, M. and Maschio, M.D. and Sawamiphak, S. and Filosa, A.
Current Biology 32 (7): 1497-1510. 11 April 2022

Retinoids are not linked to risk of multiple sclerosis: a Danish nationwide cohort study.
Cortes-Figueiredo, F. and Nielsen, N.M. and Stenager, E. and Paul, F. and Hallas, J. and Kristensen, K.B.
European Journal of Neurology 2 (1): 247-256. 18 January 2022

Combining callers improves the detection of copy number variants from whole-genome sequencing.
Coutelier, M. and Holtgrewe, M. and Jäger, M. and Flöttman, R. and Mensah, M.A. and Spielmann, M. and Krawitz, P. and Horn, D. and Beule, D. and Mundlos, S.
European Journal of Human Genetics 30 (2): 178-186. February 2022

Svep1 stabilises developmental vascular anastomosis in reduced flow conditions.
Coxam, B. and Collins, R.T. and Hußmann, M. and Huisman, Y. and Meier, K. and Jung, S. and Bartels-Klein, E. and Szymborska, A. and Finotto, L. and Helker, C.S.M. and Stainier, D.Y.R. and Schulte-Merker, S. and Gerhardt, H.
Development 149 (6): dev199858. 24 March 2022

Myogenic vasoconstriction requires canonical G(q/11) signaling of the angiotensin II type 1 receptor.
Cui, Y. and Kassmann, M. and Nickel, S. and Zhang, C. and Alenina, N. and Anistan, Y.M. and Schleifenbaum, J. and Bader, M. and Welsh, D.G. and Huang, Y. and Gollasch, M.
Journal of the American Heart Association 11 (4): e022070. 15 February 2022

Hemostatic management in an infant with neuroblastoma and severe hemophilia B with extended half-life recombinant factor IX fusion protein.
Cuntz, F. and Deubzer, H.E. and Schulte, J.H. and Nimtz-Talaska, A. and Eggert, A. and Holzhauer, S.
Journal of Pediatric Hematology Oncology 44 (1): e246-e249. 1 January 2022

Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension.
Dahale, S. and Ruiz-Orera, J. and Silhavy, J. and Hübner, N. and van Heesch, S. and Pravenec, M. and Atanur, S.S.
Life Science Alliance 5 (4): e202101234. April 2022

Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases.
Damerau, A. and Kirchner, M. and Pfeiffenberger, M. and Ehlers, L. and Do Nguyen, D.H. and Mertins, P. and Bartek, B. and Maleitzke, T. and Palmowski, Y. and Hardt, S. and Winkler, T. and Buttgereit, F. and Gaber, T.
Metabolic Engineering 72 : 116-132. July 2022

Diagnostik, Therapie und die Bedeutung der Lebensqualität von Patienten mit chronischem Koronarsyndrom [Diagnostics, therapy and the importance of quality of life in patients with chronic coronary syndrome. Results oft the general practitioner care study ALTHEA].
Dechend, R.
MMW Fortschritte der Medizin 164 (Suppl 6): 11-17. 22 April 2022

B(1) inhomogeneity correction of RARE MRI at low SNR: quantitative in vivo (19)F MRI of mouse neuroinflammation with a cryogenically-cooled transceive surface radiofrequency probe.
Delgado, P.R. and Kuehne, A. and Aravina, M. and Millward, J.M. and Vazquez, A. and Starke, L. and Waiczies, H. and Pohlmann, A. and Niendorf, T. and Waiczies, S.
Magnetic Resonance in Medicine 87 (4): 1952-1970. April 2022

Traveling volunteers: a multi-vendor, multi-center study on reproducibility and comparability of 4D flow derived aortic hemodynamics in cardiovascular magnetic resonance.
Demir, A. and Wiesemann, S. and Erley, J. and Schmitter, S. and Trauzeddel, R.F. and Pieske, B. and Hansmann, J. and Kelle, S. and Schulz-Menger, J.
Journal of Magnetic Resonance Imaging 55 (1): 211-222. January 2022

Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S. and Bittner, A. and Frick, M. and Kase, J. and Hoffmann, J. and Trenker, C. and Keller, U. and Bogner, C. and Hüttmann, A. and Dürig, J. and Janz, M. and Mathas, S. and Marks, R. and Krohn, U. and Na, I.K. and Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 63 (1): 84-92. January 2022

Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
Dieckmann, S. and Strohmeyer, A. and Willershäuser, M. and Maurer, S.F. and Wurst, W. and Marschall, S. and Hrabě de Angelis, M. and Kühn, R. and Worthmann, A. and Fuh, M.M. and Heeren, J. and Köhler, N. and Pauling, J.K. and Klingenspor, M.
American Journal of Physiology Endocrinology and Metabolism 322 (2): E85-E100. February 2022

Motion-compensated fat-water imaging for 3D cardiac MRI at ultra-high fields.
Dietrich, S. and Aigner, C.S. and Mayer, J. and Kolbitsch, C. and Schulz-Menger, J. and Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 87 (6): 2621-2636. June 2022

NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
Doffo, J. and Bamopoulos, S.A. and Köse, H. and Orben, F. and Zang, C. and Pons, M. and den Dekker, A.T. and Brouwer, R.W.W. and Baluapuri, A. and Habringer, S. and Reichert, M. and Illendula, A. and Krämer, O.H. and Schick, M. and Wolf, E. and van IJcken, W.F.J. and Esposito, I. and Keller, U. and Schneider, G. and Wirth, M.
Proceedings of the National Academy of Sciences of the United States of America 119 (9): e2105691119. 1 March 2022

Deep learning for prediction of population health costs.
Drewe-Boss, P. and Enders, D. and Walker, J. and Ohler, U.
BMC Medical Informatics and Decision Making 22 (1): 32. 3 February 2022

Gender differences in perceptions and attitudes of medical students towards neurosurgery: a german nationwide survey.
Efe, I.E. and Aliyeva, I. and Beyaztas, D. and Swiatek, V.M. and Esene, I.N. and Abdulrauf, S.I.
World Neurosurgery 2 April 2022 (In Press)

An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils.
Ellson, C.D. and Goretti Riça, I. and Kim, J.S. and Huang, Y.M.M. and Lim, D. and Mitra, T. and Hsu, A. and Wei, E.X. and Barrett, C.D. and Otterbein, L.E. and Hauser, C.J. and Wahl, M. and Delbrück, H. and Heinemann, U. and Oschkinat, H. and Chang, C.E.A. and Yaffe, M.B.
Journal of Molecular Biology 434 (9): 167533. 15 May 2022

The spontaneous course of human herpesvirus 6 DNA-associated myocarditis and the effect of immunosuppressive intervention.
Elsanhoury, A. and Kühl, U. and Stautner, B. and Klein, O. and Krannich, A. and Morris, D. and Willner, M. and Jankowska, E. and Klingel, K. and Van Linthout, S. and Tschöpe, C.
Viruses 14 (2): 299. February 2022

Evaluating metallic artefact of biodegradable magnesium-based implants in magnetic resonance imaging.
Espiritu, J. and Berangi, M. and Yiannakou, C. and Silva, E. and Francischello, R. and Kuehne, A. and Niendorf, T. and Könneker, S. and Willumeit-Römer, R. and Seitz, J.M.
Bioactive Materials 15 : 382-391. September 2022

Polymer physics reveals a combinatorial code linking 3D chromatin architecture to 1D chromatin states.
Esposito, A. and Bianco, S. and Chiariello, A.M. and Abraham, A. and Fiorillo, L. and Conte, M. and Campanile, R. and Nicodemi, M.
Cell Reports 38 (13): 110601. 29 March 2022

Development of a machine learning approach for local-scale ozone forecasting: application to Kennewick, WA.
Fan, K. and Dhammapala, R. and Harrington, K. and Lamastro, R. and Lamb, B. and Lee, Y.
Frontiers in Big Data 5 : 781309. 10 February 2022

Post-operative cognitive impairment: a cognitive epidemiology perspective.
Feinkohl, I.
Journal of Intelligence 10 (1): 18. 11 March 2022

CHIP-related epigenetic age acceleration correlates with CHIP clone size in patients with high morbidity.
Feldkamp, J.D. and Vetter, V.M. and Arends, C.M. and Lang, T.J.L. and Bullinger, L. and Damm, F. and Demuth, I. and Frick, M.
Haematologica 3 March 2022 (In Press)

Isotropic 3D compressed sensing (CS) based sequence is comparable to 2D-LGE in left ventricular scar quantification in different disease entities.
Fenski, M. and Grandy, T.H. and Viezzer, D. and Kertusha, S. and Schmidt, M. and Forman, C. and Schulz-Menger, J.
International Journal of Cardiovascular Imaging 3 March 2022 (In Press)

Recent analytical approaches for the study of bioavailability and metabolism of bioactive phenolic compounds.
Fernández-Ochoa, Á. and Cádiz-Gurrea, M.L. and Fernández-Moreno, P. and Rojas-García, A. and Arráez-Román, D. and Segura-Carretero, A.
Molecules 27 (3): 777. 25 January 2022

Presurgical thalamus volume in postoperative delirium: a longitudinal observational cohort study in older patients.
Fislage, M. and Feinkohl, I. and Pischon, T. and Spies, C.D. and Borchers, F. and Winterer, G. and Zacharias, N.
Anesthesia and Analgesia 20 April 2022 (In Press)

Subcortical volumes as early predictors of fatigue in multiple sclerosis.
Fleischer, V. and Ciolac, D. and Gonzalez-Escamilla, G. and Grothe, M. and Strauss, S. and Molina Galindo, L.S. and Radetz, A. and Salmen, A. and Lukas, C. and Klotz, L. and Meuth, S.G. and Bayas, A. and Paul, F. and Hartung, H.P. and Heesen, C. and Stangel, M. and Wildemann, B. and Bergh, F.T. and Tackenberg, B. and Kümpfel, T. and Zettl, U.K. and Knop, M. and Tumani, H. and Wiendl, H. and Gold, R. and Bittner, S. and Zipp, F. and Groppa, S. and Muthuraman, M.
Annals of Neurology 91 (2): 192-202. February 2022

Differentiation of cerebral neoplasms with vessel size imaging (VSI).
Foda, A. and Kellner, E. and Gunawardana, A. and Gao, X. and Janz, M. and Kufner, A. and Khalil, A.A. and Geran, R. and Mekle, R. and Fiebach, J.B. and Galinovic, I.
Clinical Neuroradiology 32 (1): 239-248. March 2022

Therapy switches in fingolimod-treated patients with multiple sclerosis: long-term experience from the German MS Registry.
Frahm, N. and Fneish, F. and Ellenberger, D. and Flachenecker, P. and Paul, F. and Warnke, C. and Kleinschnitz, C. and Parciak, T. and Krefting, D. and Hellwig, K. and Haas, J. and Rommer, P.S. and Stahmann, A. and Zettl, U.K.
Neurology and Therapy 11 (1): 319–336. March 2022

Analysis of adherent cell culture lysates with low metabolite concentrations using the Biocrates AbsoluteIDQ p400 HR kit.
Fritsche-Guenther, R. and Gloaguen, Y. and Eisenberger, A. and Kirwan, J.A.
Scientific Reports 12 (1): 7933. 13 May 2022

Microbiome and metabolome features of the cardiometabolic disease spectrum.
Fromentin, S. and Forslund, S.K. and Chechi, K. and Aron-Wisnewsky, J. and Chakaroun, R. and Nielsen, T. and Tremaroli, V. and Ji, B. and Prifti, E. and Myridakis, A. and Chilloux, J. and Andrikopoulos, P. and Fan, Y. and Olanipekun, M.T. and Alves, R. and Adiouch, S. and Bar, N. and Talmor-Barkan, Y. and Belda, E. and Caesar, R. and Coelho, L.P. and Falony, G. and Fellahi, S. and Galan, P. and Galleron, N. and Helft, G. and Hoyles, L. and Isnard, R. and Le Chatelier, E. and Julienne, H. and Olsson, L. and Pedersen, H.K. and Pons, N. and Quinquis, B. and Rouault, C. and Roume, H. and Salem, J.E. and Schmidt, T.S.B. and Vieira-Silva, S. and Li, P. and Zimmermann-Kogadeeva, M. and Lewinter, C. and Søndertoft, N.B. and Hansen, T.H. and Gauguier, D. and Gøtze, J.P. and Køber, L. and Kornowski, R. and Vestergaard, H. and Hansen, T. and Zucker, J.D. and Hercberg, S. and Letunic, I. and Bäckhed, F. and Oppert, J.M. and Nielsen, J. and Raes, J. and Bork, P. and Stumvoll, M. and Segal, E. and Clément, K. and Dumas, M.E. and Ehrlich, S.D. and Pedersen, O.
Nature Medicine 28 (2): 303-314. 17 February 2022

Identification and validation of small molecule analytes in mouse plasma by liquid chromatography–tandem mass spectrometry: A case study of misidentification of a short-chain fatty acid with a ketone body.
García-Rivera, Mariel A. and Fernández-Ochoa, Á. and Brüning, U. and Fritsche-Guenther, R. and Kirwan, J.A.
Talanta 242 : 123298. 15 May 2022

The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.
Garipler, G. and Lu, C. and Morrissey, Al. and Lopez-Zepeda, L.S. and Pei, Y. and Vidal, S.E. and Zen Petisco Fiore, A.P. and Aydin, B. and Stadtfeld, M. and Ohler, U. and Mahony, S. and Sanjana, N.E. and Mazzoni, E.O.
Cell Reports 38 (11): 110524. 15 March 2022

Hypertension in pregnancy: diagnosis, blood pressure goals, and pharmacotherapy: a scientific statement from the American Heart Association.
Garovic, V.D. and Dechend, R. and Easterling, T. and Karumanchi, S.A. and McMurtry Baird, S. and Magee, L.A. and Rana, S. and Vermunt, J.V. and August, P.
Hypertension 79 (2): e21-e41. February 2022

Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg, P. and Astaburuaga-García, R. and Bonaguro, L. and Brumhard, S. and Michalick, L. and Lippert, L.J. and Kostevc, T. and Gäbel, C. and Schneider, M. and Streitz, M. and Demichev, V. and Gemünd, I. and Barone, M. and Tober-Lau, P. and Helbig, E.T. and Hillus, D. and Petrov, L. and Stein, J. and Dey, H.P. and Paclik, D. and Iwert, C. and Mülleder, M. and Aulakh, S.K. and Djudjaj, S. and Bülow, R.D. and Mei, H.E. and Schulz, A.R. and Thiel, A. and Hippenstiel, S. and Saliba, A.E. and Eils, R. and Lehmann, I. and Mall, M.A. and Stricker, S. and Röhmel, J. and Corman, V.M. and Beule, D. and Wyler, E. and Landthaler, M. and Obermayer, B. and von Stillfried, S. and Boor, P. and Demir, M. and Wesselmann, H. and Suttorp, N. and Uhrig, A. and Müller-Redetzky, H. and Nattermann, J. and Kuebler, W.M. and Meisel, C. and Ralser, M. and Schultze, J.L. and Aschenbrenner, A.C. and Thibeault, C. and Kurth, F. and Sander, L.E. and Blüthgen, N. and Sawitzki, B.
Cell 185 (3): 493-512. 3 February 2022

The role of intraspinal sensory neurons in the control of quadrupedal locomotion.
Gerstmann, K. and Jurčić, N. and Blasco, E. and Kunz, S. and de Almeida Sassi, F. and Wanaverbecq, N. and Zampieri, N.
Current Biology 4 May 2022 (In Press)

Improving robustness of automatic cardiac function quantification from cine magnetic resonance imaging using synthetic image data.
Gheorghiță, B.A. and Itu, L.M. and Sharma, P. and Suciu, C. and Wetzl, J. and Geppert, C. and Ali, M.A.A. and Lee, A.M. and Piechnik, S.K. and Neubauer, S. and Petersen, S.E. and Schulz-Menger, J. and Chițiboi, T.
Scientific Reports 12 (1): 2391. 14 February 2022

Deep learning-assisted peak curation for large-scale LC-MS metabolomics.
Gloaguen, Y. and Kirwan, J.A. and Beule, D.
Analytical Chemistry 94 (12): 4930-4937. 29 March 2022

An unusual aspartic acid cluster in the reovirus attachment fiber s1 mediates stability at low pH and preserves trimeric organization.
Glorani, G. and Ruwolt, M. and Holton, N. and Loll, B. and Neu, U.
Journal of Virology 96 (8): e0033122. April 2022

Expression of circ_Satb1 is decreased in mesial temporal lobe epilepsy and regulates dendritic spine morphology.
Gomes-Duarte, A. and Venø, M.T. and de Wit, M. and Senthilkumar, K. and Broekhoven, M.H. and van den Herik, J. and Heeres, F.R. and van Rossum, D. and Rybiczka-Tesulov, M. and Legnini, I. and van Rijen, P.C. and van Eijsden, P. and Gosselaar, P.H. and Rajewsky, N. and Kjems, J. and Vangoor, V.R. and Pasterkamp, R.J.
Frontiers in Molecular Neuroscience 15 : 832133. 3 March 2022

Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension.
Grabowski, K. and Herlan, L. and Witten, A. and Qadri, F. and Eisenreich, A. and Lindner, D. and Schädlich, M. and Schulz, A. and Subrova, J. and Mhatre, K.N. and Primessnig, U. and Plehm, R. and van Linthout, S. and Escher, F. and Bader, M. and Stoll, M. and Westermann, D. and Heinzel, F.R. and Kreutz, R.
Hypertension Research 45 : 292-307. January 2022

Age of red cells for transfusion and outcomes in patients with ARDS.
Graw, J.A. and Bünger, V. and Materne, L.A. and Krannich, A. and Balzer, F. and Francis, R.C.E. and Pruß, A. and Spies, C.D. and Kuebler, W.M. and Weber-Carstens, S. and Menk, M. and Hunsicker, O.
Journal of Clinical Medicine 11 (1): 245. 4 January 2022

Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.
Greco, T.M. and Secker, C. and Silva Ramos, E. and Federspiel, J.D. and Liu, J.P. and Perez, A.M. and Al-Ramahi, I. and Cantle, J.P. and Carroll, J.B. and Botas, J. and Zeitlin, S.O. and Wanker, E.E. and Cristea, I.M.
Cell Systems 13 (4): 304-320.e5. 22 April 2022

Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.
Grinat, J. and Kosel, F. and Goveas, N. and Kranz, A. and Alexopoulou, D. and Rajewsky, K. and Sigal, M. and Stewart, A.F. and Heuberger, J.
Life Science Alliance 5 (4): e202101187. April 2022

Statins aggravate the risk of insulin resistance in human muscle.
Grunwald, S.A. and Haafke, S. and Grieben, U. and Kassner, U. and Steinhagen-Thiessen, E. and Spuler, S.
International Journal of Molecular Sciences 23 (4): 2398. 21 February 2022

Phenotypic spectrum of BLM- and RMI1-related Bloom syndrome.
Gönenc, I.I. and Elcioglu, N.H. and Martinez Grijalva, C. and Aras, S. and Großmann, N. and Praulich, I. and Altmüller, J. and Kaulfuß, S. and Li, Y. and Nürnberg, P. and Burfeind, P. and Yigit, G. and Wollnik, B.
Clinical Genetics 101 (5-6): 559-564. May 2022

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel, G. and Conlon, T.M. and Jeridi, A. and Kim, R. and Ertüz, Z. and Lang, N.J. and Ansari, M. and Novikova, M. and Jiang, D. and Strunz, M. and Gaianova, M. and Hollauer, C. and Gabriel, C. and Angelidis, I. and Doll, S. and Pestoni, J.C. and Edelmann, S.L. and Kohlhepp, M.S. and Guillot, A. and Bassler, K. and Van Eeckhoutte, H.P. and Kayalar, Ö. and Konyalilar, N. and Kanashova, T. and Rodius, S. and Ballester-López, C. and Genes Robles, C.M. and Smirnova, N. and Rehberg, M. and Agarwal, C. and Krikki, I. and Piavaux, B. and Verleden, S.E. and Vanaudenaerde, B. and Königshoff, M. and Dittmar, G. and Bracke, K.R. and Schultze, J.L. and Watz, H. and Eickelberg, O. and Stoeger, T. and Burgstaller, G. and Tacke, F. and Heissmeyer, V. and Rinkevich, Y. and Bayram, H. and Schiller, H.B. and Conrad, M. and Schneider, R. and Yildirim, A.Ö.
Nature Communications 13 (1): 1303. 14 March 2022

Introduction of Lazy Luna an automatic software-driven multilevel comparison of ventricular function quantification in cardiovascular magnetic resonance imaging.
Hadler, T. and Wetzl, J. and Lange, S. and Geppert, C. and Fenski, M. and Abazi, E. and Gröschel, J. and Ammann, C. and Wenson, F. and Töpper, A. and Däuber, S. and Schulz-Menger, J.
Scientific Reports 12 (1): 6629. 22 April 2022

Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats.
Haduch, A. and Danek, P.J. and Kuban, W. and Pukło, R. and Alenina, N. and Gołębiowska, J. and Popik, P. and Bader, M. and Daniel, W.A.
Neurochemistry International 152 : 105223. January 2022

Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS).
Haffke, M. and Freitag, H. and Rudolf, G. and Seifert, M. and Doehner, W. and Scherbakov, N. and Hanitsch, L. and Wittke, K. and Bauer, S. and Konietschke, F. and Paul, F. and Bellmann-Strobl, J. and Kedor, C. and Scheibenbogen, C. and Sotzny, F.
Journal of Translational Medicine 20 (1): 138. 22 March 2022

Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism.
Haghikia, A. and Zimmermann, F. and Schumann, P. and Jasina, A. and Roessler, J. and Schmidt, D. and Heinze, P. and Kaisler, J. and Nageswaran, V. and Aigner, A. and Ceglarek, U. and Cineus, R. and Hegazy, A.N. and van der Vorst, E.P.C. and Döring, Y. and Strauch, C.M. and Nemet, I. and Tremaroli, V. and Dwibedi, C. and Kränkel, N. and Leistner, D.M. and Heimesaat, M.M. and Bereswill, S. and Rauch, G. and Seeland, U. and Soehnlein, O. and Müller, D.N. and Gold, R. and Bäckhed, F. and Hazen, S.L. and Haghikia, A. and Landmesser, U.
European Heart Journal 43 (6): ehab644. 7 February 2022

An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
Hahn, T. and Ernsting, J. and Winter, N.R. and Holstein, V. and Leenings, R. and Beisemann, M. and Fisch, L. and Sarink, K. and Emden, D. and Opel, N. and Redlich, R. and Repple, J. and Grotegerd, D. and Meinert, S. and Hirsch, J.G. and Niendorf, T. and Endemann, B. and Bamberg, F. and Kröncke, T. and Bülow, R. and Völzke, H. and von Stackelberg, O. and Sowade, R.F. and Umutlu, L. and Schmidt, B. and Caspers, S. and Kugel, H. and Kircher, T. and Risse, B. and Gaser, C. and Cole, J.H. and Dannlowski, U. and Berger, K.
Science Advances 8 (1): eabg9471. 7 January 2022

Long-term connectome analysis reveals reshaping of visual, spatial networks in a model with vascular dementia features.
Hall, G.R. and Boehm-Sturm, P. and Dirnagl, U. and Finke, C. and Foddis, M. and Harms, C. and Koch, S.P. and Kuchling, J. and Madan, C.R. and Mueller, S. and Sassi, C. and Sotiropoulos, S.N. and Trueman, R.C. and Wallis, M.D. and Yildirim, F. and Farr, T.D.
Stroke 53 (5): 1735-1745. May 2022

Rational design of highly potent, selective, and bioavailable SGK1 protein kinase inhibitors for the treatment of osteoarthritis.
Halland, N. and Schmidt, F. and Weiss, T. and Li, Z. and Czech, J. and Saas, J. and Ding-Pfennigdorff, D. and Dreyer, M.K. and Strübing, C. and Nazare, M.
Journal of Medicinal Chemistry 65 (2): 1567-1584. 27 January 2022

Sensitivity and specificity of loss of heterozygosity analysis for the classification of rare germline variants in BRCA1/2: results of the observational AGO-TR1 study (NCT02222883).
Hauke, J. and Harter, P. and Ernst, C. and Burges, A. and Schmidt, S. and Reuss, A. and Borde, J. and De Gregorio, N. and Dietrich, D. and El-Balat, A. and Kayali, M. and Gevensleben, H. and Hilpert, F. and Altmüller, J. and Heimbach, A. and Meier, W. and Schoemig-Markiefka, B. and Thiele, H. and Kimmig, R. and Nürnberg, P. and Kast, K. and Richters, L. and Sehouli, J. and Schmutzler, R.K. and Hahnen, E.
Journal of Medical Genetics 59 (3): 248-252. March 2022

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca, P. and Vonficht, D. and Schnell, A. and Uckelmann, H.J. and Bollhagen, A. and Mahmoud, M.A.A. and Landua, S.L. and van der Salm, E. and Trautmann, C. and Raffel, S. and Grünschläger, F. and Lutz, R. and Ghosh, M. and Renders, S. and Correia, N. and Donato, E. and Dixon, K.O. and Hirche, C. and Andresen, C. and Robens, Cl. and Werner, P.S. and Boch, T. and Eisel, D. and Osen, W. and Pilz, F. and Przybylla, A. and Klein, C. and Buchholz, F. and Milsom, M.D. and Essers, M.A.G. and Eichmüller, S.B. and Hofmann, W.K. and Nowak, D. and Hübschmann, D. and Hundemer, M. and Thiede, C. and Bullinger, L. and Müller-Tidow, C. and Armstrong, S.A. and Trumpp, A. and Kuchroo, V.K. and Haas, S.
Cell Stem Cell 29 (5): 760-775.e10. 5 May 2022

In vivo stiffness of multiple sclerosis lesions is similar to that of normal-appearing white matter.
Herthum, H. and Hetzer, S. and Scheel, M. and Shahryari, M. and Braun, J. and Paul, F. and Sack, I.
Acta Biomaterialia 138 : 410-421. 15 January 2022

Locus-conserved circular RNA cZNF292 controls endothelial cell flow responses.
Heumüller, A.W. and Jones, A. N. and Mourão, A. and Klangwart, M. and Shi, C. and Wittig, I. and Fischer, A. and Muhly Reinholz, M. and Buchmann, G.K. and Dieterich, C. and Potente, M. and Braun, T. and Grote, P. and Jaé, N. and Sattler, M. and Dimmeler, S.
Circulation Research 130 (1): 67-79. 7 January 2022

Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors.
Heynen, G.J.J.E. and Lisek, K. and Vogel, R. and Wulf-Goldenberg, A. and Alcaniz, J. and Montaudon, E. and Marangoni, E. and Birchmeier, W.
Breast Cancer Research 24 (1): 23. 1 April 2022

Inflammation and convergent placenta gene co-option contributed to a novel reproductive tissue.
Hilgers, L. and Roth, O. and Nolte, A.W. and Schüller, A. and Spanke, T. and Flury, J.M. and Utama, I.V. and Altmüller, J. and Wowor, D. and Misof, B. and Herder, F. and Böhne, A. and Schwarzer, J.
Current Biology 32 (3): 715-724. 7 February 2022

Uncoupling the excitatory amino acid transporter 2 from its C-terminal interactome restores synaptic glutamate clearance at corticostriatal synapses and alleviates mutant huntingtin-induced hypokinesia.
Hirschberg, S. and Dvorzhak, A. and Rasooli-Nejad, S.M.A. and Angelov, S. and Kirchner, M. and Mertins, P. and Lättig-Tünnemann, G. and Harms, C. and Schmitz, D. and Grantyn, R.
Frontiers in Cellular Neuroscience 15 : 792652. 31 January 2022

Microglia/macrophage derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model.
Huang, Y. and Motta, E. and Nanvuma, C. and Kuhrt, L.D. and Yuan, Y. and Xia, P. and Lubas, M. and Zhu, S. and Schnauss, M. and Qazi, N. and Hu, F. and Zhang, H. and Lei, T. and Synowitz, M. and Flüh, C. and Kettenmann, H.
Cell Reports 39 (2): 110670. 12 April 2022

CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage.
Hyun, J.W. and Kim, Y. and Kim, K.H. and Kim, S.H. and Olesen, M.N. and Asgari, N. and Siritho, S. and Paul, F. and Kim, H.J.
Journal of Neuroinflammation 19 (1): 86. 12 April 2022

Physical performance and non-esterified fatty acids in men and women after transcatheter aortic valve implantation (TAVI).
Härdrich, M. and Haase-Fielitz, A. and Fielitz, J. and Boschmann, M. and Pivovarova-Ramich, O. and Pfeiffer, A.F.H. and Rudovich, N. and Weylandt, K.H. and Butter, C.
Nutrients 14 (1): 203. 2 January 2022

Costs and health-related quality of life in patients with NMO spectrum disorders and MOG-antibody-associated disease: CHANCE(NMO) study.
Hümmert, M.W. and Schöppe, L.M. and Bellmann-Strobl, J. and Siebert, N. and Paul, F. and Duchow, A. and Pellkofer, H. and Kümpfel, T. and Havla, J. and Jarius, S. and Wildemann, B. and Berthele, A. and Bergh, F.T. and Pawlitzki, M. and Klotz, L. and Kleiter, I. and Stangel, M. and Gingele, S. and Weber, M.S. and Faiss, J.H. and Pul, R. and Walter, A. and Zettl, U. and Senel, M. and Stellmann, J.P. and Häußler, V. and Hellwig, K. and Ayzenberg, I. and Aktas, O. and Ringelstein, M. and Schreiber-Katz, O. and Trebst, C.
Neurology 98 (11): e1184-e1196. 15 March 2022

Automated detection and localization of synaptic vesicles in electron microscopy images.
Imbrosci, B. and Schmitz, D. and Orlando, M.
eNeuro 9 (1): ENEURO.0400-20.2021. January 2022

Dynamics of bacteria scanning a porous environment.
Irani, E. and Mokhtari, Z. and Zippelius, A.
Physical Review Letters 128 (14): 144501. 5 April 2022

Impact of the first COVID-19 lockdown in Germany on the rate of acute infections during intensive chemotherapy for Hodgkin lymphoma.
Jacob, A.S. and Kaul, H. and Fuchs, M. and Gillessen, S. and Kreissl, S. and Pluetschow, A. and Momotow, J. and Schaub, V. and Huettmann, A. and Haenel, M. and Zimmermann, A. and Dierlamm, J. and Meissner, J. and Mathas, S. and Martin, S. and Engert, A. and Hallek, M. and Borchmann, P. and Lehmann, C.
Infection 19 February 2022 (In Press)

Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients.
Jarius, S. and Pache, F. and Körtvelyessy, P. and Jelčić, I. and Stettner, M. and Franciotta, D. and Keller, E. and Neumann, B. and Ringelstein, M. and Senel, M. and Regeniter, A. and Kalantzis, R. and Willms, J.F. and Berthele, A. and Busch, M. and Capobianco, M. and Eisele, A. and Reichen, I. and Dersch, R. and Rauer, S. and Sandner, K. and Ayzenberg, I. and Gross, C.C. and Hegen, H. and Khalil, M. and Kleiter, I. and Lenhard, T. and Haas, J. and Aktas, O. and Angstwurm, K. and Kleinschnitz, C. and Lewerenz, J. and Tumani, H. and Paul, F. and Stangel, M. and Ruprecht, K. and Wildemann, B.
Journal of Neuroinflammation 19 (1): 19. 20 January 2022

Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice.
Jensen, M. and Müller, C. and Huebner, N. and Patone, G. and Saar, K. and Choe, C.U. and Schwedhelm, E. and Zeller, T.
Scientific Reports 12 (1): 5108. 24 March 2022

Targeting cathepsin C in PR3-ANCA vasculitis.
Jerke, U. and Eulenberg-Gustavus, C. and Rousselle, A. and Nicklin, P. and Kreideweiss, S. and Grundl, M.A. and Eickholz, P. and Nickles, K. and Schreiber, A. and Korkmaz, B. and Kettritz, R.
Journal of the American Society of Nephrology 33 (5): 936-947. 15 March 2022

Accelerating clinical scale production of BCMA CAR T cells with defined maturation stages.
Joedicke, J.J. and Großkinsky, U. and Gerlach, K. and Künkele, A. and Höpken, U.E. and Rehm, A.
Molecular Therapy - Methods and Clinical Development 24 : 181-198. 10 March 2022

Cardiac surgery-related acute kidney injury - risk factors, clinical course, management suggestions.
Just, I.A. and Alborzi, F. and Godde, M. and Ott, S. and Meyer, A. and Stein, J. and Mazgareanu, S. and van der Giet, M. and Schmidt-Ott, K.M. and Falk, V. and Schoenrath, F.
Journal of Cardiothoracic and Vascular Anesthesia 36 (2): 444-451. February 2022

Significant reduced loss of bone mineral density after four vs. six cycles of R-CHOP: an analysis of the FLYER-trial.
Kaddu-Mulindwa, D. and Lesan, V. and Berdel, C. and Stilgenbauer, S. and Bewarder, M. and Thurner, L. and Witzens-Harig, M. and Viardot, A. and Soekler, M. and Keller, U. and Truemper, L. and Christofyllakis, K. and Fleser, O. and Bittenbring, J.T. and Poeschel, V. and Held, G. and Jagoda, P.
Leukemia & Lymphoma 63 (2): 326-334. February 2022

Tolerance induction through early feeding to prevent food allergy in infants with eczema (TEFFA): rationale, study design, and methods of a randomized controlled trial.
Kalb, B. and Meixner, L. and Trendelenburg, V. and Unterleider, N. and Dobbertin-Welsch, J. and Heller, S. and Dölle-Bierke, S. and Roll, S. and Lau, S. and Lee, Y.A. and Fauchère, F. and Braun, J. and Babina, M. and Altrichter, S. and Birkner, T. and Worm, M. and Beyer, K.
Trials 23 (1): 210. 12 March 2022

Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load.
Kaneshige, A. and Kaji, T. and Zhang, L. and Saito, H. and Nakamura, A. and Kurosawa, T. and Ikemoto-Uezumi, M. and Tsujikawa, K. and Seno, S. and Hori, M. and Saito, Y. and Matozaki, T. and Maehara, K. and Ohkawa, Y. and Potente, M. and Watanabe, S. and Braun, T. and Uezumi, A. and Fukada, S.I.
Cell Stem Cell 29 (2): 265-280. 3 February 2022

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M. and Lin, M. and Maertzdorf, J. and Heuberger, J. and Muellerke, S. and Zuo, X. and Vidal, R. and Shureiqi, I. and Fischer, A.S. and Sauer, S. and Berger, H. and Kidess, E. and Mollenkopf, H.J. and Tacke, F. and Meyer, T.F. and Sigal, M.
Nature Communications 13 (1): 1577. 24 March 2022

A faecal microbiota signature with high specificity for pancreatic cancer.
Kartal, E. and Schmidt, T.S.B. and Molina-Montes, E. and Rodríguez-Perales, S. and Wirbel, J. and Maistrenko, O.M. and Akanni, W.A. and Alashkar Alhamwe, B. and Alves, R.J. and Carrato, A. and Erasmus, H.P. and Estudillo, L. and Finkelmeier, F. and Fullam, A. and Glazek, A.M. and Gómez-Rubio, P. and Hercog, R. and Jung, F. and Kandels, S. and Kersting, S. and Langheinrich, M. and Márquez, M. and Molero, X. and Orakov, A. and Van Rossum, T. and Torres-Ruiz, R. and Telzerow, A. and Zych, K. and Benes, V. and Zeller, G. and Trebicka, J. and Real, F.X. and Malats, N. and Bork, P.
Gut 8 March 2022 (In Press)

Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath, J. and Du, W. and Pruene, A. and Braun, T. and Thommandru, B. and Turk, R. and Sturgeon, M.L. and Kurgan, G.L. and Amini, L. and Stein, M. and Zittel, T. and Martini, S. and Ostendorf, L. and Wilhelm, A. and Akyüz, L. and Rehm, A. and Hoepken, U.E. and Pruß, A. and Künkele, A. and Jacobi, A.M. and Volk, H.D. and Schmueck-Henneresse, M. and Stripecke, R. and Reinke, P. and Wagner, D.L.
Molecular Therapy - Methods and Clinical Development 25 : 311-330. 9 June 2022

Modular deep neural networks for automatic quality control of retinal optical coherence tomography scans.
Kauer-Bonin, J. and Yadav, S.K. and Beckers, I. and Gawlik, K. and Motamedi, S. and Zimmermann, H.G. and Kadas, E.M. and Haußer, F. and Paul, F. and Brandt, A.U.
Computers in Biology and Medicine 141 : 104822. February 2022

Real-time measurements of intracellular cAMP gradients using FRET-based cAMP nanorulers.
Kayser, C. and Lohse, M.J. and Bock, A.
Methods in Molecular Biology 2483 : 1-13. 2022

Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes.
Khedkar, S. and Smyshlyaev, G. and Letunic, I. and Maistrenko, O.M. and Coelho, L.P. and Orakov, A. and Forslund, S.K. and Hildebrand, F. and Luetge, M. and Schmidt, T.S.B. and Barabas, O. and Bork, P.
Nucleic Acids Research 50 (6): 3155-3168. 8 April 2022

Proteolytic cleavage of the extracellular domain affects signaling of parathyroid hormone 1 receptor.
Klenk, C. and Hommers, L. and Lohse, M.J.
Frontiers in Endocrinology 13 : 839351. 22 February 2022

Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies.
Kleo, K. and Jovanovic, V.M. and Arndold, A. and Lehmann, A. and Lammert, H. and Berg, E. and Harloff, H. and Treese, C. and Hummel, M. and Daum, S.
Journal of Cancer Research and Clinical Oncology 5 March 2022 (In Press)

Meconium microbiome of very preterm infants across Germany.
Klopp, J. and Ferretti, P. and Meyer, C.U. and Hilbert, K. and Haiß, A. and Marißen, J. and Henneke, P. and Hudalla, H. and Pirr, S. and Viemann, D. and Zemlin, M. and Forslund, S.K. and Härtel, C. and Bork, P. and Gehring, S. and Van Rossum, T.
mSphere 7 (1): e0080821. 23 February 2022

Antibiotic resistance genes in river biofilms: a metagenomic approach toward the identification of sources and candidate hosts.
Kneis, D. and Berendonk, T.U. and Forslund, S.K. and Hess, S.
Environmental Science and Technology 25 April 2022 (In Press)

Association of ultra-rare coding variants with genetic generalized epilepsy: a case-control whole exome sequencing study.
Koko, M. and Motelow, J.E. and Stanley, K.E. and Bobbili, D.R. and Dhindsa, R.S. and May, P.
Epilepsia 63 (3): 723-735. March 2022

Simultaneous dimensionality reduction and integration for single-cell ATAC-seq data using deep learning.
Kopp, W. and Akalin, A. and Ohler, U.
Nature Machine Intelligence 4 (2): 162-168. February 2022

EASIX and severe endothelial complications after CD19-directed CAR-T Cell therapy-a cohort study.
Korell, F. and Penack, O. and Mattie, M. and Schreck, N. and Benner, A. and Krzykalla, J. and Wang, Z. and Schmitt, M. and Bullinger, L. and Müller-Tidow, C. and Dreger, P. and Luft, T.
Frontiers in Immunology 13 : 877477. 8 April 2022

Deletion in the Y chromosome of B10.BR-Y(del) mice alters transcription from MSYq genes and has moderate effect on DNA methylation.
Kotarska, K. and Doniec, A. and Korostyński, M. and Piechota, M. and Gołas, A. and Lisowski, P. and Styrna, J.
Reproductive Biology 22 (2): 100614. June 2022

Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society.
Kroke, A. and Schmidt, A. and Amini, A.M. and Kalotai, N. and Lehmann, A. and Haardt, J. and Bauer, J.M. and Bischoff-Ferrari, H.A. and Boeing, H. and Egert, S. and Ellinger, S. and Kühn, T. and Louis, S. and Lorkowski, S. and Nimptsch, K. and Remer, T. and Schulze, M.B. and Siener, R. and Stangl, G.I. and Volkert, D. and Zittermann, A. and Buyken, A.E. and Watzl, B. and Schwingshackl, L.
European Journal of Nutrition 61 (4): 2091-2101. June 2022

Paracrine interleukin 6 induces cerebral remodeling at early stages after unilateral common carotid artery occlusion in mice.
Kuffner, M.T.C. and Koch, S.P and Kirchner, M. and Mueller, S. and Lips, J. and An, J. and Mertins, P. and Dirnagl, U. and Endres, M. and Boehm-Sturm, P. and Harms, C. and Hoffmann, C.J.
Frontiers in Cardiovascular Medicine 8 : 805095. 27 January 2022

Small cell lung cancer stem cells display mesenchymal properties and exploit immune checkpoint pathways in activated cytotoxic T lymphocytes.
Kursunel, M.A. and Taskiran, E.Z. and Tavukcuoglu, E. and Yanik, H. and Demirag, F. and Karaosmanoglu, B. and Ozbay, F.G. and Uner, A. and Esendagli, D. and Kizilgoz, D. and Yilmaz, U. and Esendagli, G.
Cancer Immunology Immunotherapy 71 (2): 445-459. February 2022

Genome engineering in rodents - status quo and perspectives.
Kühn, R.
Laboratory Animals 56 (1): 83-87. 1 February 2022

Magnetic field-induced interactions between phones containing magnets and cardiovascular implantable electronic devices: Flip it to be safe?
Lacour, P. and Dang, P.L. and Heinzel, F.R. and Parwani, A.S. and Bähr, F. and Kucher, A. and Hohendanner, F. and Niendorf, T. and Rahimi, F. and Saha, N. and Han, H. and Rubarth, K. and Sherif, M. and Boldt, L.H. and Pieske, B. and Blaschke, F.
Heart Rhythm 19 (3): 372-380. March 2022

Interleukin 8 in postoperative delirium - preliminary findings from two studies.
Lammers-Lietz, F. and Akyuz, L. and Feinkohl, I. and Lachmann, C. and Pischon, T. and Volk, H.D. and von Häfen, C. and Yürek, F. and Winterer, G. and Spies, C.D.
Brain Behavior & Immunity - Health 20 : 100419. March 2022

Rapid single-cell identification of Epstein-Barr virus-specific T-cell receptors for cellular therapy.
Lammoglia Cobo, M.F. and Welters, C. and Rosenberger, L. and Leisegang, M. and Dietze, K. and Pircher, C. and Penter, L. and Gary, R. and Bullinger, L. and Takvorian, A. and Moosmann, A. and Dornmair, K. and Blankenstein, T. and Kammertöns, T. and Gerbitz, A. and Hansmann, L.
Cytotherapy 4 May 2022 (In Press)

Sox9 is required for nail bed differentiation and digit tip regeneration.
Lao, M. and Hurtado, A. and de Castro, A.C. and Burgos, M. and Jiménez, R. and Barrionuevo, F.J.
Journal of Investigative Dermatology 7 April 2022 (In Press)

Heteroplasmy of wild type mitochondrial DNA variants in mice causes metabolic heart disease with pulmonary hypertension and frailty.
Lechuga-Vieco, A.V. and Latorre-Pellicer, A. and Calvo, E. and Torroja, C. and Pellico, J. and Acín-Pérez, R. and García-Gil, M.L. and Santos, A. and Bagwan, N. and Bonzon-Kulichenko, E. and Magni, R. and Benito, M. and Justo-Méndez, R. and Simon, A.K. and Sánchez-Cabo, F. and Vázquez, J. and Ruíz-Cabello, J. and Enríquez, J.A.
Circulation 145 (12): 1084-1101. 5 April 2022

B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice.
Lee, M.S.J. and Inoue, T. and Ise, W. and Matsuo-Dapaah, J. and Wing, J.B. and Temizoz, B. and Kobiyama, K. and Hayashi, T. and Patil, A. and Sakaguchi, S. and Simon, A.K. and Bezbradica, J.S. and Nagatoishi, S. and Tsumoto, K. and Inoue, J.I. and Akira, S. and Kurosaki, T. and Ishii, K.J. and Coban, C.
Journal of Experimental Medicine 219 (2): e20211336. 7 February 2022

A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies.
Lessel, D. and Rading, K. and Campbell, S.E. and Thiele, H. and Altmüller, J. and Gordon, L.B. and Kubisch, C.
American Journal of Medical Genetics A 188 (1): 216-223. January 2022

Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors.
Li, C. and Wang, H. and Gil, S. and Germond, A. and Fountain, C. and Baldessari, A. and Kim, J. and Liu, Z. and Georgakopoulou, A. and Radtke, S. and Raskó, T. and Pande, A. and Chiang, C. and Chin, E. and Yannaki, E. and Izsvak, Z. and Papayannopoulou, T. and Kiem, H.P. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 24 : 127-141. 10 March 2022

Fly Cell Atlas: a single-nucleus transcriptomic atlas of the adult fruit fly.
Li, H. and Janssens, J. and De Waegeneer, M. and Kolluru, S.S. and Davie, K. and Gardeux, V. and Saelens, W. and David, F.P.A. and Brbić, M. and Spanier, K. and Leskovec, J. and McLaughlin, C.N. and Xie, Q. and Jones, R.C. and Brueckner, K. and Shim, J. and Tattikota, S.G. and Schnorrer, F. and Rust, K. and Nystul, T.G. and Carvalho-Santos, Zi. and Ribeiro, C. and Pal, S. and Mahadevaraju, S. and Przytycka, T.M. and Allen, A.M. and Goodwin, S.F. and Berry, C.W. and Fuller, M.T. and White-Cooper, H. and Matunis, E.L. and DiNardo, S. and Galenza, A. and O'Brien, L.E. and Dow, J.A.T. and Jasper, H. and Oliver, B. and Perrimon, N. and Deplancke, B. and Quake, S.R. and Luo, L. and Aerts, S.
Science 375 (6584): eabk2432. 4 March 2022

Phosphoinositide conversion inactivates R-RAS and drives metastases in breast cancer.
Li, H. and Prever, L. and Hsu, M.Y. and Lo, W.T. and Margaria, J.P. and De Santis, M.C. and Zanini, C. and Forni, M. and Novelli, F. and Pece, S. and Di Fiore, P.P. and Porporato, P.E. and Martini, M. and Belabed, H. and Nazare, M. and Haucke, V. and Gulluni, F. and Hirsch, E.
Advanced Science 9 (9): e2103249. 25 March 2022

Diffusion-weighted magnetic resonance imaging in rat kidney using two-dimensional navigated, interleaved echo-planar imaging at 7.0 T.
Liu, Q. and Xu, Z. and Zhao, K. and Hoge, W.S. and Zhang, X. and Mei, Y. and Lu, Q. and Niendorf, T. and Feng, Y.
NMR in Biomedicine 35 (5): e4652. May 2022

Hemodialysis and plasma oxylipin biotransformation in peripheral tissue.
Liu, T. and Dogan, I. and Rothe, M. and Kunz, J.V. and Knauf, F. and Gollasch, M. and Luft, F.C. and Gollasch, B.
Metabolites 12 (1): 34. 4 January 2022

Bioaccumulation of blood long-chain fatty acids during hemodialysis.
Liu, T. and Dogan, I. and Rothe, M. and Reichardt, J. and Knauf, F. and Gollasch, M. and Luft, F.C. and Gollasch, B.
Metabolites 12 (3): 269. 21 March 2022

Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo, W.T. and Zhang, Y. and Vadas, O. and Roske, Y. and Gulluni, F. and De Santis, M.C. and Zagar, A.V. and Stephanowitz, H. and Hirsch, E. and Liu, F. and Daumke, O. and Kudryashev, M. and Haucke, V.
Nature Structural & Molecular Biology 29 (3): 218-228. March 2022

Targeted analysis of cell-free circulating tumor DNA is suitable for early relapse and actionable target detection in patients with neuroblastoma.
Lodrini, M. and Graef, J. and Thole-Kliesch, T.M. and Astrahantseff, K. and Sprüssel, A. and Grimaldi, M. and Peitz, C. and Linke, R.B. and Hollander, J.F. and Lankes, E. and Künkele, A. and Oevermann, L. and Schwabe, G. and Fuchs, J. and Szymansky, A. and Schulte, J.H. and Hundsdoerfer, P. and Eckert, C. and Amthauer, H. and Eggert, A. and Deubzer, H.E.
Clinical Cancer Research 28 (9): 1809-1820. 1 May 2022

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase in B cell lymphomas.
Lopez, C. and Schleussner, N. and Bernhart, S.H. and Kleinheinz, K. and Sungalee, S. and Sczakiel, H.L. and Kretzmer, H. and Toprak, U.H. and Glaser, S. and Wagener, R. and Ammerpohl, O. and Bens, S. and Giefing, M. and Sanchez, J.C.G. and Apic, G. and Hubschmann, D. and Janz, M. and Kreuz, M. and Mottok, A. and Müller, J.M. and Seufert, J. and Hoffmann, S. and Korbel, J.O. and Russell, R.B. and Schule, R. and Trumper, L. and Klapper, W. and Radlwimmer, B. and Lichter, P. and Kuppers, R. and Schlesner, M. and Mathas, S. and Siebert, R.
Haematologica 28 April 2022 (In Press)

Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.
Lorenz, C. and Zink, A. and Henke, M.T. and Staege, S. and Mlody, B. and Bünning, M. and Wanker, E. and Diecke, S. and Schuelke, M. and Prigione, A.
Stem Cell Research 61 : 102742. May 2022

Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders.
Lu, A. and Zimmermann, H.G. and Specovius, S. and Motamedi, S. and Chien, C. and Bereuter, C. and Lana-Peixoto, M.A. and Fontenelle, M.A. and Ashtari, F. and Kafieh, R. and Dehghani, A. and Pourazizi, M. and Pandit, L. and D'Cunha, A. and Kim, H.J. and Hyun, J.W. and Jung, S.K. and Leocani, L. and Pisa, M. and Radaelli, M. and Siritho, S. and May, E.F. and Tongco, C. and De Sèze, J. and Senger, T. and Palace, J. and Roca-Fernández, A. and Leite, M.I. and Sharma, S.M. and Stiebel-Kalish, H. and Asgari, N. and Soelberg, K.K. and Martinez-Lapiscina, E.H. and Havla, J. and Mao-Draayer, Y. and Rimler, Z. and Reid, A. and Marignier, R. and Cobo-Calvo, A. and Altintas, A. and Tanriverdi, U. and Yildirim, R. and Aktas, O. and Ringelstein, M. and Albrecht, P. and Tavares, I.M. and Bichuetti, D.B. and Jacob, A. and Huda, S. and Soto de Castillo, I. and Petzold, A. and Green, A.J. and Yeaman, M.R. and Smith, T.J. and Cook, L. and Paul, F. and Brandt, A.U. and Oertel, F.C.
Journal of Neurology Neurosurgery and Psychiatry 93 (2): 188-195. February 2022

A congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig, L. and Lareau, C.A. and Bao, E.L. and Liu, N. and Utsugisawa, T. and Tseng, A.M. and Myers, S.A. and Verboon, J.M. and Ulirsch, J.C. and Luo, W. and Muus, C. and Fiorini, C. and Olive, M.E. and Vockley, C.M. and Munschauer, M. and Hunter, A. and Ogura, H. and Yamamoto, T. and Inada, H. and Nakagawa, S. and Ozono, S. and Subramanian, V. and Chiarle, R. and Glader, B. and Carr, S.A. and Aryee, M.J. and Kundaje, A. and Orkin, S. and Regev, A. and McCavit, T. and Kanno, H. and Sankaran, V.G.
Blood 139 (16): 2534-2546. 21 April 2022

Skin sodium accumulates in psoriasis and reflects disease severity.
Maifeld, A. and Wild, J. and Karlsen, T.V. and Rakova, N. and Wistorf, E. and Linz, P. and Jung, R. and Birukov, A. and Gimenez-Rivera, V.A. and Wilck, N. and Bartolomaeus, T. and Dechend, R. and Kleinewietfeld, M. and Forslund, S.K. and Krause, A. and Kokolakis, G. and Philipp, S. and Clausen, B.E. and Brand, A. and Waisman, A. and Kurschus, F.C. and Wegner, J. and Schultheis, M. and Luft, F.C. and Boschmann, M. and Kelm, M. and Wiig, H. and Kuehne, T. and Müller, D.N. and Karbach, S. and Markó, L.
Journal of Investigative Dermatology 142 (1): 166-178. January 2022

Loss of endothelial cytochrome P450 reductase induces vascular dysfunction in mice.
Malacarne, P.F. and Ratiu, C. and Gajos-Draus, A. and Müller, N. and Lopez, M. and Pflüger-Müller, B. and Ding, X. and Warwick, T. and Oo, J. and Siragusa, M. and Angioni, C. and Günther, S. and Weigert, A. and Geißlinger, G. and Lütjohann, D. and Schunck, W.H. and Fleming, I. and Brandes, R.P. and Rezende, F.
Hypertension 79 (6): 1216-1226. June 2022

Imaging and analysis of neuronal mitochondria in murine acute brain slices.
Malla, B. and Hauser, A. and Niesner, R. and Infante-Duarte, C.
Journal of Neuroscience Methods 372 : 109558. 15 April 2022

Teriflunomide preserves neuronal activity and protects mitochondria in brain slices exposed to oxidative stress.
Malla, B. and Liotta, A. and Bros, H. and Ulshöfer, R. and Paul, F. and Hauser, A.E. and Niesner, R. and Infante-Duarte, C.
International Journal of Molecular Sciences 23 (3): 1538. 28 January 2022

AQP4-IgG-seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.
Marignier, R. and Pittock, S.J. and Paul, F. and Kim, H.J. and Bennett, J. L. and Weinshenker, B.G. and Wingerchuk, D.M. and Green, A.J. and Fujihara, K. and Cutter, G. and Aktas, O. and Hartung, H.P. and Drappa, J. and Ratchford, J.N. and She, D. and Smith, M. and Rees, W. and Cimbora, D. and Katz, E. and Cree, B.A.C.
Multiple Sclerosis and Related Disorders 57 : 103356. January 2022

Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F. and Jerke, U. and Rolle, S. and Daumke, O. and Kettritz, R.
Journal of Biological Chemistry 298 (3): 101598. March 2022

Genomic variants reducing expression of two endocytic receptors in 46,XY differences of sex development.
Marko, H.L. and Hornig, N.C. and Betz, R.C. and Holterhus, P.M. and Altmüller, J. and Thiele, H. and Fabiano, M. and Schweikert, H.U. and Braun, D. and Schweizer, U.
Human Mutation 43 (3): 420-433. March 2022

The Cl(-)-channel TMEM16A is involved in the generation of cochlear Ca(2+) waves and promotes the refinement of auditory brainstem networks in mice.
Maul, A. and Huebner, A.K. and Strenzke, N. and Moser, T. and Rübsamen, R. and Jovanovic, S. and Hübner, C.A.
eLife 11 : e72251. 24 February 2022

Assessing the relationship of patient reported outcome measures with functional status in dysferlinopathy: a Rasch analysis approach.
Mayhew, A.G. and James, M.K. and Moore, U. and Sutherland, H. and Jacobs, M. and Feng, J. and Lowes, L.P. and Alfano, L.N. and Muni Lofra, R. and Rufibach, L.E. and Rose, K. and Duong, T. and Bello, L. and Pedrosa-Hernández, I. and Holsten, S. and Sakamoto, C. and Canal, A. and Sánchez-Aguilera Práxedes, N. and Thiele, S. and Siener, C. and Vandevelde, B. and DeWolf, B. and Maron, E. and Gordish-Dressman, H. and Hilsden, H. and Guglieri, M. and Hogrel, J.Y. and Blamire, A.M. and Carlier, P.G. and Spuler, S. and Day, J.W. and Jones, K.J. and Bharucha-Goebel, D.X. and Salort-Campana, E. and Pestronk, A. and Walter, M.C. and Paradas, C. and Stojkovic, T. and Mori-Yoshimura, M. and Bravver, E. and Díaz-Manera, J. and Pegoraro, E. and Mendell, J.R. and Straub, V.
Frontiers in Neurology 13 : 828525. 10 March 2022

Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
McGarvey, A.C. and Kopp, W. and Vučićević, D. and Mattonet, K. and Kempfer, R. and Hirsekorn, A. and Bilić, I. and Gil, M. and Trinks, A. and Merks, A.M. and Panáková, D. and Pombo, A. and Akalin, A. and Junker, J.P. and Stainier, D.Y.R. and Garfield, D. and Ohler, U. and Lacadie, S.A.
Cell Genomics 2 (1): 100083. 13 January 2022

Analyses of murine lymph node endothelial cell subsets using single-cell RNA sequencing and spectral flow cytometry.
Menzel, L. and Zschummel, M. and Rehm, A.
STAR Protocols 3 (2): 101267. 17 June 2022

Cutting edge: Serum but not mucosal antibody responses are associated with pre-existing SARS-CoV-2 spike cross-reactive CD4(+) T cells following BNT162b2 vaccination in the elderly.
Meyer-Arndt, L. and Schwarz, T. and Loyal, L. and Henze, L. and Kruse, B. and Dingeldey, M. and Gürcan, K. and Uyar-Aydin, Z. and Müller, M.A. and Drosten, C. and Paul, F. and Sander, L.E. and Demuth, I. and Lauster, R. and Giesecke-Thiel, C. and Braun, J. and Corman, V.M. and Thiel, A.
Journal of Immunology 208 (5): 1001-1008. 1 March 2022

Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations.
Miller, T.E. and Lareau, C.A. and Verga, J.A. and DePasquale, E.A.K. and Liu, V. and Ssozi, D. and Sandor, K. and Yin, Y. and Ludwig, L.S. and El Farran, C.A. and Morgan, D.M. and Satpathy, A.T. and Griffin, G.K. and Lane, A.A. and Love, J.C. and Bernstein, B.E. and Sankaran, V.G. and van Galen, P.
Nature Biotechnology 24 February 2022

Suicide nanoplasmids coding for ribosome-inactivating proteins.
Mitdank, H. and Tröger, M. and Sonntag, A. and Shirazi, N.A. and Woith, E. and Fuchs, H. and Kobelt, D. and Walther, W. and Weng, A.
European Journal of Pharmaceutical Sciences 170 : 106107. 1 March 2022

Diet quality indices and gastrointestinal cancer risk: results from the Lifelines study.
Moazzen, S. and Cortes-Ibañez, F.O. and van der Vegt, B. and Alizadeh, B.Z. and de Bock, G.H.
European Journal of Nutrition 61 : 317-327. February 2022

Targeting angiotensin type 2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice.
Mohammed, M. and Johnson, D.N. and Wang, L.A. and Harden, S.W. and Sheng, W. and Spector, E.A. and Elsaafien, K. and Bader, M. and Steckelings, U.M. and Scott, K.A. and Frazier, C.J. and Sumners, C. and Krause, E.G. and de Kloet, A.D.
Cardiovascular Research 118 (3): 883-896. 21 February 2022

In vitro and in vivo anti‐epileptic efficacy of eslicarbazepine acetate in a mouse model of KCNQ2‐related self‐limited epilepsy.
Monni, L. and Kraus, L. and Dipper‐Wawra, M. and Soares‐da‐Silva, P. and Maier, N. and Schmitz, D. and Holtkamp, M. and Fidzinski, P.
British Journal of Pharmacology 179 (1): 84-102. January 2022

Cardiac and pulmonary findings in dysferlinopathy: a 3-year, longitudinal study.
Moore, U. and Fernandez-Torron, R. and Jacobs, M. and Gordish, H. and Diaz-Manera, J. and James, M.K. and Mayhew, A.G. and Harris, E. and Guglieri, M. and Rufibach, L.E. and Feng, J. and Blamire, A.M. and Carlier, P.G. and Spuler, S. and Day, J.W. and Jones, K.J. and Bharucha-Goebel, D.X. and Salort-Campana, E. and Pestronk, A. and Walter, M.C. and Paradas, C. and Stojkovic, T. and Mori-Yoshimura, M. and Bravver, E. and Pegoraro, E. and Lowes, L.P. and Mendell, J.R. and Bushby, K. and Bourke, J. and Straub, V.
Muscle & Nerve 65 (5): 531-540. May 2022

Genomic basis of syndromic short stature in an Algerian patient cohort.
Moosa, S. and Chentli, F. and Altmüller, J. and Bögershausen, N. and Nürnberg, P. and Yigit, G. and Li, Y. and Wollnik, B.
American Journal of Medical Genetics A 188 (2): 606-612. February 2022

Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus-specific.
Muehleman, D.L. and Crocini, C. and Swearingen, A.R. and Ozeroff, C.D. and Leinwand, L.A.
American Journal of Physiology Heart and Circulatory Physiology 322 (5): H785-H797. May 2022

Deep Visual Proteomics defines single-cell identity and heterogeneity.
Mund, A. and Coscia, F. and Kriston, A. and Hollandi, R. and Kovács, F. and Brunner, A.D. and Migh, E. and Schweizer, L. and Santos, A. and Bzorek, M. and Naimy, S. and Rahbek-Gjerdrum, L.M. and Dyring-Andersen, B. and Bulkescher, J. and Lukas, C. and Eckert, M.A. and Lengyel, E. and Gnann, C. and Lundberg, E. and Horvath, P. and Mann, M.
Nature Biotechnology 19 May 2022

Political knowledge and misinformation in the era of social media: evidence from the 2015 UK election.
Munger, K. and Egan, P.J. and Nagler, J. and Ronen, J. and Tucker, J.
British Journal of Political Science 52 (1): 107 - 127. January 2022

Increased salt intake decreases diet-induced thermogenesis in healthy volunteers: a randomized placebo-controlled study.
Mähler, A. and Klamer, S. and Maifeld, A. and Bartolomaeus, H. and Markó, L. and Chen, C.Y. and Forslund, S.K. and Boschmann, M. and Müller, D.N. and Wilck, N.
Nutrients 14 (2): 253. 7 January 2022

Choroid plexus volume in multiple sclerosis vs neuromyelitis optica spectrum disorder: a retrospective, cross-sectional analysis.
Müller, J. and Sinnecker, T. and Wendebourg, M.J. and Schläger, R. and Kuhle, J. and Schädelin, S. and Benkert, P. and Derfuss, T. and Cattin, P. and Jud, C. and Spiess, F. and Amann, M. and Lincke, T. and Barakovic, M. and Cagol, A. and Tsagkas, C. and Parmar, K. and Pröbstel, A.K. and Reimann, S. and Asseyer, S. and Duchow, A. and Brandt, A. and Ruprecht, K. and Hadjikhani, N. and Fukumoto, S. and Watanabe, M. and Masaki, K. and Matsushita, T. and Isobe, N. and Kira, J.I. and Kappos, L. and Würfel, J. and Granziera, C. and Paul, F. and Yaldizli, Ö.
Neurology Neuroimmunology & Neuroinflammation 9 (3): e1147. May 2022

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D. and Ramberger, E. and Bohl, S.R. and Dolnik, A. and Steinebach, C. and Conrad, T. and Müller, S. and Popp, O. and Kull, M. and Haji, M. and Gütschow, M. and Döhner, H. and Walther, W. and Keller, U. and Bullinger, L. and Mertins, P. and Krönke, J.
Nature Communications 13 (1): 1009. 23 February 2022

External validation of the HCM Risk-Kids model for predicting sudden cardiac death in childhood hypertrophic cardiomyopathy.
Norrish, G. and Qu, C. and Field, E. and Cervi, E. and Khraiche, D. and Klaassen, S. and Ojala, T.H. and Sinagra, G. and Yamazawa, H. and Marrone, C. and Popoiu, A. and Centeno, F. and Schouvey, S. and Olivotto, I. and Day, S.M. and Colan, S. and Rossano, J. and Wittekind, S.G. and Saberi, S. and Russell, M. and Helms, A. and Ingles, J. and Semsarian, C. and Elliott, P.M. and Ho, C.Y. and Omar, R.Z. and Kaski, J.P.
European Journal of Preventive Cardiology 29 (4): 678-686. 30 March 2022

Generation of a NES-mScarlet red fluorescent reporter human iPSC line for live cell imaging and flow cytometric analysis and sorting using CRISPR-Cas9-mediated gene editing.
Nouri, P. and Zimmer, A. and Brüggemann, S. and Friedrich, R. and Kühn, R. and Prakash, N.
Cells 11 (2): 268. 13 January 2022

Effect of atmospheric aging on soot particle toxicity in lung cell models at the air-liquid interface: differential toxicological impacts of biogenic and anthropogenic secondary organic aerosols (SOAs).
Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Martens, P. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Pardo, M. and Gröger, T. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Rudich, Y. and Zimmermann, R.
Environmental Health Perspectives 130 (2): 27003. 3 February 2022

A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
Patsalos, A. and Halasz, L. and Medina-Serpas, M.A. and Berger, W.K. and Daniel, B. and Tzerpos, P. and Kiss, M. and Nagy, G. and Fischer, C. and Simandi, Z. and Varga, T. and Nagy, L.
Journal of Experimental Medicine 219 (1): e20210420. 3 January 2022

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K. and Leunig, A. and Kaiser, R. and Joppich, M. and Brambs, S. and Janjic, A. and Popp, O. and Nixdorf, D. and Fumagalli, V. and Schmidt, N. and Polewka, V. and Anjum, A. and Knottenberg, V. and Eivers, L. and Wange, L.E. and Gold, C. and Kirchner, M. and Muenchhoff, M. and Hellmuth, J.C. and Scherer, C. and Rubio-Acero, R. and Eser, T. and Deák, F. and Puchinger, K. and Kuhl, N. and Linder, A. and Saar, K. and Tomas, L. and Schulz, C. and Wieser, A. and Enard, W. and Kroidl, I. and Geldmacher, C. and von Bergwelt-Baildon, M. and Keppler, O.T. and Munschauer, M. and Iannacone, M. and Zimmer, R. and Mertins, P. and Hubner, N. and Hoelscher, M. and Massberg, S. and Stark, K. and Nicolai, L.
Nature Communications 13 (1): 1018. 23 February 2022

Treatment with ribociclib shows favourable immunomodulatory effects in patients with hormone receptor-positive breast cancer-findings from the RIBECCA trial.
Peuker, C.A. and Yaghobramzi, S. and Grunert, C. and Keilholz, L and Gjerga, E. and Hennig, S. and Schaper, S. and Na, I.K. and Keller, U. and Brucker, S. and Decker, T. and Fasching, P. and Fehm, T. and Janni, W. and Kümmel, S. and Schneeweiss, A. and Schuler, M. and Lüftner, D. and Busse, A.
European Journal of Cancer 162 : 45-55. February 2022

Engineering, decoding and systems-level characterization of chimpanzee cytomegalovirus.
Phan, Q.V. and Bogdanow, B. and Wyler, E. and Landthaler, M. and Liu, F. and Hagemeier, C. and Wiebusch, L.
PLoS Pathogens 18 (1): e1010193. 4 January 2022

Rabies anterograde monosynaptic tracing allows identification of postsynaptic circuits receiving distinct somatosensory input.
Pimpinella, S. and Sauve, I. and Dietrich, S. and Zampieri, N.
Neuroscience 491 : 75-86. 21 May 2022

Gut microbiome composition in obese and non-obese persons: a systematic review and meta-analysis.
Pinart, M. and Dötsch, A. and Schlicht, K. and Laudes, M. and Bouwman, J. and Forslund, S.K. and Pischon, T. and Nimptsch, K.
Nutrients 14 (1): 12. 1 January 2022

Cardiovascular magnetic resonance in children with suspected myocarditis: current practice and applicability of adult protocols.
Pitak, B. and Opgen-Rhein, B. and Schubert, S. and Reineker, K. and Wiegand, G. and Boecker, D. and Rentzsch, A. and Ruf, B. and Özcan, S. and Wannenmacher, B. and Pickardt, T. and Seidel, F. and Messroghli, D.
Cardiology in the Young : 1-9. 24 January 2022 (In Press)

EACVI survey on hypertrophic cardiomyopathy.
Podlesnikar, T. and Cardim, N. and Ajmone Marsan, N. and D'Andrea, A. and Cameli, M. and Popescu, B.A. and Schulz-Menger, J. and Stankovic, I. and Toplisek, J. and Maurer, G. and Haugaa, K.H. and Dweck, M.R.
European Heart Journal - Cardiovascular Imaging 23 (5): 590-597. May 2022

Missense variant E1295K of sodium channel SCN5A associated with recurrent ventricular fibrillation and myocardial inflammation.
Poller, W. and Escher, F. and Haas, J. and Heidecker, B. and Schultheiss, H.P. and Attanasio, P. and Skurk, C. and Haghikia, A. and Meder, B. and Klaassen, S.
JACC: Case Reports 4 (5): 280-286. 2 March 2022

Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders.
Porubsky, D. and Höps, W. and Ashraf, H. and Hsieh, P.H. and Rodriguez-Martin, B. and Yilmaz, F. and Ebler, J. and Hallast, P. and Maggiolini, F.A.M. and Harvey, W.T. and Henning, B. and Audano, P.A. and Gordon, D.S. and Ebert, P. and Hasenfeld, P. and Benito, E. and Zhu, Q. and Lee, C. and Antonacci, F. and Steinrücken, M. and Beck, C.R. and Sanders, A.D. and Marschall, T. and Eichler, E.E. and Korbel, J.O.
Cell 6 May 2022 (In Press)

Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics.
Pryszlak, A. and Wenzel, T. and Seitz, K.W. and Hildebrand, F. and Kartal, E. and Cosenza, M.R. and Benes, V. and Bork, P. and Merten, C.A.
Cell Reports Methods 2 (1): 100137. 24 January 2022

P2X7 receptor antagonist reduces fibrosis and inflammation in a mouse model of alpha-sarcoglycan muscular dystrophy.
Raffaghello, L. and Principi, E. and Baratto, S. and Panicucci, C. and Pintus, S. and Antonini, F. and Del Zotto, G. and Benzi, A. and Bruzzone, S. and Scudieri, P. and Minetti, C. and Gazzerro, E. and Bruno, C.
Pharmaceuticals 15 (1): 89. 13 January 2022

FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer.
Raschzok, N. and Stintzing, S. and Heinemann, V. and Rauch, G. and Ricke, J. and Guckenberger, M. and Kurreck, A. and Alig, A.H.S. and Stahler, A. and Bullinger, L. and Schmelzle, M. and Schöning, W. and Lurje, G. and Krenzien, F. and Haase, O. and Rau, B. and Gebauer, B. and Sauer, I.M. and Pratschke, J. and Modest, D.P.
BMC Cancer 22 (1): 359. 2 April 2022

Placental CD4(+) T cells from preeclamptic patients cause autoantibodies to the angiotensin II type I receptor and hypertension in a pregnant rat model of preeclampsia.
Reeve, K.E. and Deer, E. and Amaral, L.M. and Cornelius, D.C. and Herrock, O. and Harmon, A.C. and Campbell, N. and Fitzgerald, S. and Ibrahim, T. and Wallukat, G. and Dechend, R. and LaMarca, B.
Exploration of Medicine 3 : 99-111. 25 February 2022

EBAG9 controls CD8(+) T cell memory formation responding to tumor challenge in mice.
Rehm, A. and Wirges, A. and Hoser, D. and Fischer, C. and Herda, S. and Gerlach, K. and Sauer, S. and Willimsky, G. and Hoepken, U.E.
JCI Insight 28 April 2022 (In Press)

Comparison of FACS and PCR for detection of BCMA-CAR-T cells.
Reichman, A. and Kunz, A. and Joedicke, J.J. and Höpken, U.E. and Keib, A. and Neuber, B. and Sedloev, D. and Wang, L. and Jiang, G. and Hückelhoven-Krauss, A. and Eberhardt, F. and Müller-Tidow, C. and Wermke, M. and Rehm, A. and Schmitt, M. and Schmitt, A.
International Journal of Molecular Sciences 23 (2): 903. 14 January 2022

SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies.
Reincke, S.M. and Yuan, M. and Kornau, H.C. and Corman, V.M. and van Hoof, S. and Sánchez-Sendin, E. and Ramberger, M. and Yu, W. and Hua, Y. and Tien, H. and Schmidt, M.L. and Schwarz, T. and Jeworowski, L.M. and Brandl, S.E. and Rasmussen, H.F. and Homeyer, M.A. and Stöffler, L. and Barner, M. and Kunkel, D. and Huo, S. and Horler, J. and von Wardenburg, N. and Kroidl, I. and Eser, T.M. and Wieser, A. and Geldmacher, C. and Hoelscher, M. and Gänzer, H. and Weiss, G. and Schmitz, D. and Drosten, C. and Prüss, H. and Wilson, I.A. and Kreye, J.
Science 375 (6582): 782-787. 18 February 2022

MAGED2 controls vasopressin-induced aquaporin-2 expression in collecting duct cells.
Reusch, B. and Bartram, M.P. and Dafinger, C. and Palacio-Escat, N. and Wenzel, A. and Fenton, R.A. and Saez-Rodriguez, J. and Schermer, B. and Benzing, T. and Altmüller, J. and Beck, B.B. and Rinschen, M.M.
Journal of Proteomics 252 : 104424. 10 February 2022

Biallelic PAN2 variants in individuals with a syndromic neurodevelopmental disorder and multiple congenital anomalies.
Reuter, M.S. and Zech, M. and Hempel, M. and Altmüller, J. and Heung, T. and Pölsler, L. and Santer, R. and Thiele, H. and Trost, B. and Kubisch, C. and Scherer, S.W. and Rudnik-Schöneborn, S. and Bassett, A.S. and Lessel, D.
European Journal of Human Genetics 30 (5): 611–618. May 2022

90-yttrium-ibritumomab tiuxetan as first-line treatment for follicular lymphoma: updated efficacy and safety results at an extended median follow-up of 9.6 years.
Rieger, K. and De Filippi, R. and Lindén, O. and Viardot, A. and Hess, G. and Lerch, K. and Neumeister, P. and Stroux, A. and Peuker, C.A. and Pezzutto, A. and Pinto, A. and Keller, U. and Scholz, C.W.
Annals of Hematology 101 (4): 781-788. April 2022

Mental and behavioural responses to Bahá'í fasting: looking behind the scenes of a religiously motivated intermittent fast using a mixed methods approach.
Ring, R.M. and Eisenmann, C. and Kandil, F.I. and Steckhan, N. and Demmrich, S. and Klatte, C. and Kessler, C.S. and Jeitler, M. and Boschmann, M. and Michalsen, A. and Blakeslee, S.B. and Stöckigt, B. and Stritter, W. and Koppold-Liebscher, D.A.
Nutrients 14 (5): 1038. 28 February 2022

Interleukin-6 receptor blockade in treatment-refractory MOG-IgG-associated disease and neuromyelitis optica spectrum disorders.
Ringelstein, M. and Ayzenberg, I. and Lindenblatt, G. and Fischer, K. and Gahlen, A. and Novi, G. and Hayward-Könnecke, H. and Schippling, S. and Rommer, P.S. and Kornek, B. and Zrzavy, T. and Biotti, D. and Ciron, J. and Audoin, B. and Berthele, A. and Giglhuber, K. and Zephir, H. and Kümpfel, T. and Berger, R. and Röther, J. and Häußler, V. and Stellmann, J.P. and Whittam, D. and Jacob, A. and Kraemer, M. and Gueguen, A. and Deschamps, R. and Bayas, A. and Hümmert, M.W. and Trebst, C. and Haarmann, A. and Jarius, S. and Wildemann, B. and Grothe, M. and Siebert, N. and Ruprecht, K. and Paul, F. and Collongues, N. and Marignier, R. and Levy, M. and Karenfort, M. and Deppe, M. and Albrecht, P. and Hellwig, K. and Gold, R. and Hartung, H.P. and Meuth, S.G. and Kleiter, I. and Aktas, O.
Neurology Neuroimmunology & Neuroinflammation 9 (1): e1100. January 2022

WASp controls oriented migration of endothelial cells to achieve functional vascular patterning.
Rosa, A. and Giese, W. and Meier, K. and Alt, S. and Klaus-Bergmann, A. and Edgar, L.T. and Bartels, E. and Collins, R. and Szymborska, A. and Coxam, B. and Bernabeu, M.O. and Gerhardt, H.
Development 149 (3): dev200195. February 2022

JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia.
Rosenberg, J.M. and Peters, J.M. and Hughes, T. and Lareau, C.A. and Ludwig, L.S. and Massoth, L.R. and Austin-Tse, C. and Rehm, H.L. and Bryson, B. and Chen, Y.B. and Regev, A. and Shalek, A.K. and Fortune, S.M. and Sykes, D.B.
Med 3 (1): 42-57.e5. 14 January 2022

CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Rousselle, A. and Sonnemann, J. and Amann, K. and Mildner, A. and Lodka, D. and Kling, L. and Bieringer, M. and Schneider, U. and Leutz, A. and Enghard, P. and Kettritz, R. and Schreiber, A.
Annals of the Rheumatic Diseases 13 April 2022 (In Press)

Estimation and testing of Wilcoxon–Mann–Whitney effects in factorial clustered data designs.
Rubarth, K. and Sattler, P. and Zimmermann, H.G. and Konietschke, F.
Symmetry 14 (2): 244. February 2022

Proposal for post hoc quality control in instrumented motion analysis using markerless motion capture: development and usability study.
Röhling, H.M. and Althoff, P. and Arsenova, R. and Drebinger, D. and Gigengack, N. and Chorschew, A. and Kroneberg, D. and Rönnefarth, M. and Ellermeyer, T. and Rosenkranz, S.C. and Heesen, C. and Behnia, B. and Hirano, S. and Kuwabara, S. and Paul, F. and Brandt, A.U. and Schmitz-Hübsch, T.
JMIR Human Factors 9 (2): e26825. 1 April 2022

Diagnostic accuracy of cerebrospinal fluid biomarkers for the differential diagnosis of sporadic Creutzfeldt-Jakob disease: a (network) meta-analysis.
Rübsamen, N. and Pape, S. and Konigorski, S. and Zapf, A. and Rücker, G. and Karch, A.
European Journal of Neurology 29 (5): 1366-1376. May 2022

Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
Rücker, F.G. and Du, L. and Luck, T.J. and Benner, A. and Krzykalla, J. and Gathmann, I. and Voso, M.T. and Amadori, S. and Prior, T.W. and Brandwein, J.M. and Appelbaum, F.R. and Medeiros, B.C. and Tallman, M.S. and Savoie, L. and Sierra, J. and Pallaud, C. and Sanz, M.A. and Jansen, J.H. and Niederwieser, D. and Fischer, T. and Ehninger, G. and Heuser, M. and Ganser, A. and Bullinger, L. and Larson, R.A. and Bloomfield, C.D. and Stone, R.M. and Döhner, H. and Thiede, C. and Döhner, K.
Leukemia 36 (1): 90-99. January 2022

Epigenetic targeting of transposon relics: beating the dead horses of the genome?
Sammarco, I. and Pieters, J. and Salony, S. and Toman, I. and Zolotarov, G. and Lafon Placette, C.
Epigenetics 4 January 2022 (In Press)

Local microcircuitry of PaS shows distinct and common features of excitatory and inhibitory connectivity.
Sammons, R.P. and Tzilivaki, A. and Schmitz, D.
Cerebral Cortex 32 (1): 76-92. January 2022

KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in Plasmodium falciparum-infected erythrocytes.
Sanchez, C.P. and Patra, P. and Chang, S.Y.S. and Karathanasis, C. and Hanebutte, L. and Kilian, N. and Cyrklaff, M. and Heilemann, M. and Schwarz, U.S. and Kudryashev, M. and Lanzer, M.
Molecular Microbiology 117 (2): 274-292. February 2022

A knowledge graph to interpret clinical proteomics data.
Santos, A. and Colaço, A.R. and Nielsen, A.B. and Niu, L. and Strauss, M. and Geyer, P.E. and Coscia, F. and Albrechtsen, N.J.W. and Mundt, F. and Jensen, L.J. and Mann, M.
Nature Biotechnology 40 (5): 692-702. 22 May 2022

Adolescence is a sensitive period for prefrontal microglia to act on cognitive development.
Schalbetter, S.M. and von Arx, A.S. and Cruz-Ochoa, N. and Dawson, K. and Ivanov, A. and Mueller, F.S. and Lin, H.Y. and Amport, R. and Mildenberger, W. and Mattei, D. and Beule, D. and Földy, C. and Greter, M. and Notter, T. and Meyer, U.
Science Advances 8 (9): eabi6672. 4 March 2022

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
Schick, M. and Zhang, L. and Maurer, S. and Maurer, H.C. and Isaakaidis, K. and Schneider, L. and Patra, U. and Schunck, K. and Rohleder, E. and Hofstetter, J. and Baluapuri, A. and Scherger, A.K. and Slotta-Huspenina, J. and Hettler, F. and Weber, J. and Engleitner, T. and Maresch, R. and Slawska, J. and Lewis, R. and Istvanffy, R. and Habringer, S. and Steiger, K. and Baiker, A. and Oostendorp, R.A.J. and Miething, C. and Lenhof, H.P. and Bassermann, F. and Chapuy, B. and Wirth, M. and Wolf, E. and Rad, R. and Müller, S. and Keller, U.
Nature Communications 13 (1): 281. 12 January 2022

Hypo- und Hypernatriämien auf der Intensivstation : Fallstricke des Volumenmanagements [Hypo- and hypernatremia in the intensive care unit : pitfalls in volume management].
Schilling, J. and Compton, F. and Schmidt-Ott, K.
Wiener klinisches Magazin 25 : 32-37. 10 January 2022

The synaptic scaffold protein MPP2 interacts with GABA(A) receptors at the periphery of the postsynaptic density of glutamatergic synapses.
Schmerl, B. and Gimber, N. and Kuropka, B. and Stumpf, A. and Rentsch, J. and Kunde, S.A. and von Sivers, J. and Ewers, H. and Schmitz, D. and Freund, C. and Schmoranzer, J. and Rademacher, N. and Shoichet, S.A.
PLoS Biology 20 (3): e3001503. 21 March 2022

B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
Schmid, V.K. and Khadour, A. and Ahmed, N. and Brandl, C. and Nitschke, L. and Rajewsky, K. and Jumaa, H. and Hobeika, E.
Haematologica 13 January 2022 (In Press)

Familial cleft tongue caused by a unique translation initiation codon variant in TP63.
Schmidt, J. and Schreiber, G. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Li, Y. and Kaulfuß, S. and Funke, R. and Wilken, B. and Yigit, G. and Wollnik, B.
European Journal of Human Genetics 30 (2): 211-218. February 2022

Prävention des akuten Nierenversagens [Prevention of acute kidney injury].
Schmidt-Ott, K.M. and Swolinsky, J.
Deutsche Medizinische Wochenschrift 147 (5): 236-245. March 2022

Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.
Schmiester, M. and Tranter, E. and Lorusso, A. and Blaschke, F. and Geisel, D. and Bullinger, L. and Damm, F. and Na, I.K.
BMC Cardiovascular Disorders 22 (1): 31. 4 February 2022

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M. and Schwarzer, A. and Jayavelu, A.K. and Hsu, C.J. and Kirkpatrick, J. and Döhner, K. and Perner, F. and Eifert, T. and Huber, N. and Arreba-Tutusaus, P. and Dolnik, A. and Assi, S.A. and Nafria, M. and Jiang, L. and Dai, Y.T. and Chen, Z. and Chen, S.J. and Kellaway, S.G. and Ptasinska, A. and Ng, E.S. and Stanley, E.G. and Elefanty, A.G. and Buschbeck, M. and Bierhoff, H. and Brodt, S. and Matziolis, G. and Fischer, K.D. and Hochhaus, A. and Chen, C.W. and Heidenreich, O. and Mann, M. and Lane, S.W. and Bullinger, L. and Ori, A. and von Eyss, B. and Bonifer, C. and Heidel, F.
Blood 139 (7): 1080-1097. 17 February 2022

Helicobacter pylori - neue Aspekte kommender Leitlinien [Helicobacter pylori - new aspects of forthcoming guidelines].
Schulz, C. and Fischbach, W. and Sigal, M. and Schütte, K. and Suerbaum, S. and Malfertheiner, P.
Internist 63 (4): 367–371. 1 March 2022

Whole-body magnetic resonance imaging in the large population-based German National Cohort study: predictive capability of automated image quality assessment for protocol repetitions.
Schuppert, C. and von Krüchten, R. and Hirsch, J.G. and Rospleszcz, S. and Hoinkiss, D.C. and Selder, S. and Köhn, A. and von Stackelberg, O. and Peters, A. and Völzke, H. and Kröncke, T. and Niendorf, T. and Forsting, M. and Hosten, N. and Hendel, T. and Pischon, T. and Jöckel, K.H. and Kaaks, R. and Bamberg, F. and Kauczor, H.U. and Günther, M. and Schlett, C.L.
Investigative Radiology 17 February 2022 (In Press)

On the relation between input and output distributions of scRNA-seq experiments.
Schwabe, D. and Falcke, M.
Bioinformatics 38 (5): 1336-1343. 1 March 2022

Eating patterns during pregnancy and postpartum and their association with diet quality and energy intake.
Schwedhelm, C. and Lipsky, L.M. and Temmen, C.D. and Nansel, T.R.
Nutrients 14 (6): 1167. 10 March 2022

Clinical characteristics and outcome of biopsy-proven myocarditis in children - Results of the German prospective multicentre registry "MYKKE".
Seidel, F. and Opgen-Rhein, B. and Rentzsch, A. and Boehne, M. and Wannenmacher, B. and Boecker, D. and Reineker, K. and Grafmann, M. and Wiegand, G. and Hecht, T. and Kiski, D. and Fischer, M. and Papakostas, K. and Ruf, B. and Kramp, J. and Khalil, M. and Kaestner, M. and Steinmetz, M. and Fischer, G. and Özcan, S. and Freudenthal, N. and Schweigmann, U. and Hellwig, R. and Pickardt, T. and Klingel, K. and Messroghli, D. and Schubert, S.
International Journal of Cardiology 357 : 95-104. 15 June 2022

A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants.
Shahan, R. and Hsu, C.W. and Nolan, T.M. and Cole, B.J. and Taylor, I.W. and Greenstreet, L. and Zhang, S. and Afanassiev, A. and Vlot, A.H.C. and Schiebinger, G. and Benfey, P.N. and Ohler, U.
Developmental Cell 57 (4): 543-560. 28 February 2022

K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.
Shearer, R.F. and Typas, D. and Coscia, F. and Schovsbo, S. and Kruse, T. and Mund, A. and Mailand, N.
EMBO Journal 41 (9): e110145. 2 May 2022

Amelioration of endotoxemia by a synthetic analog of Omega-3 epoxyeicosanoids.
Shikuma, A. and Kami, D. and Maeda, R. and Suzuki, Y. and Sano, A. and Taya, T. and Ogata, T. and Konkel, A. and Matoba, S. and Schunck, W.H. and Gojo, S.
Frontiers in Immunology 13 : 825171. 24 February 2022

A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish.
Singh, S.P. and Chawla, P. and Hnatiuk, A. and Kamel, M. and Silva, L.D. and Spanjaard, B. and Eski, S.E. and Janjuha, S. and Olivares-Chauvet, P. and Kayisoglu, O. and Rost, F. and Bläsche, J. and Kränkel, A. and Petzold, A. and Kurth, T. and Reinhardt, S. and Junker, J.P. and Ninov, N.
Development 149 (2): dev199853. January 2022

CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment.
Skroblyn, T. and Joedicke, J.J. and Pfau, M. and Krüger, K. and Bourquin, J.P. and Izraeli, S. and Eckert, C. and Höpken, U.E.
Journal of Pathology 6 May 2022 (In Press)

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić, S. and Prada-Medina, C.A. and Landoulsi, Z. and Ghelfi, J. and Delcambre, S. and Dietrich, C. and Jarazo, J. and Henck, J. and Balachandran, S. and Pachchek, S. and Morris, C.M. and Antony, P. and Timmermann, B. and Sauer, S. and Pereira, S.L. and Schwamborn, J.C. and May, P. and Grünewald, A. and Spielmann, M.
Brain 145 (3): 964-978. March 2022

mRNA-mediated delivery of gene editing tools to human primary muscle stem cells.
Stadelmann, C. and Di Francescantonio, S. and Marg, A. and Müthel, S. and Spuler, S. and Escobar, H.
Molecular Therapy - Nucleic Acids 28 : 47-57. 14 June 2022

Nationwide registry-based analysis of infective endocarditis risk after pulmonary valve replacement.
Stammnitz, Clara and Huscher, Dörte and Bauer, Ulrike M M and Urban, Aleksandra and Nordmeyer, Johannes and Schubert, Stephan and Photiadis, Joachim and Berger, Felix and Klaassen, S.
Journal of the American Heart Association 11 (5): e022231. 18 February 2022

DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M. and Denker, S. and Schmitt, C.A.
Cancers 14 (6): 1453. 11 March 2022

Comorbidities rather than older age define outcome in adult patients with tumors of the Ewing sarcoma family.
Striefler, J.K. and Schmiester, M. and Brandes, F. and Dörr, A. and Pahl, S. and Kaul, D. and Rau, D. and Dobrindt, E.M. and Koulaxouzidis, G. and Bullinger, L. and Märdian, S. and Flörcken, A.
Cancer Medicine 16 March 2022 (In Press)

MCT1 is a predictive marker for lenalidomide maintenance therapy in multiple myeloma.
Stroh, J. and Seckinger, A. and Heider, M. and Rudelius, M. and Eichner, R. and Schick, M. and Slawska, J. and Emde, M. and Salwender, H. and Bertsch, U. and Goldschmidt, H. and Weisel, K.C. and Scheid, C. and Keller, U. and Hose, D. and Bassermann, F.
Blood Advances 6 (2): 515-520. 25 January 2022

Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
Subramanian, S. and Busch, C.J.L. and Molawi, K. and Geirsdottir, L. and Maurizio, J. and Vargas Aguilar, S. and Belahbib, H. and Gimenez, G. and Yuda, R.A.A. and Burkon, M. and Favret, J. and Gholamhosseinian Najjar, S. and de Laval, B. and Kandalla, P.K. and Sarrazin, S. and Alexopoulou, L. and Sieweke, M.H.
Nature Immunology 23 (3): 458-468. March 2022

Skeletal muscle derived Musclin protects the heart during pathological overload.
Szaroszyk, M. and Kattih, B. and Martin-Garrido, A. and Trogisch, F.A. and Dittrich, G.M. and Grund, A. and Abouissa, A. and Derlin, K. and Meier, M. and Holler, T. and Korf-Klingebiel, M. and Völker, K. and Macedo, T.G. and Tortola, C.P. and Boschmann, M. and Huang, N. and Froese, N. and Zwadlo, C. and Malek Mohammadi, M. and Luo, X. and Wagner, M. and Cordero, J. and Geffers, R. and Batkai, S. and Thum, T. and Bork, N. and Nikolaev, V.O. and Müller, O.J. and Katus, H.A. and El-Armouche, A. and Kraft, T. and Springer, J. and Dobreva, G. and Wollert, K.C. and Fielitz, J. and von Haehling, S. and Kuhn, M. and Bauersachs, J. and Heineke, J.
Nature Communications 13 (1): 149. 10 January 2022

Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease.
Talmor-Barkan, Y. and Bar, N. and Shaul, A.A. and Shahaf, N. and Godneva, A. and Bussi, Y. and Lotan-Pompan, M. and Weinberger, A. and Shechter, A. and Chezar-Azerrad, C. and Arow, Z. and Hammer, Y. and Chechi, K. and Forslund, S.K. and Fromentin, S. and Dumas, M.E. and Ehrlich, S.D. and Pedersen, O. and Kornowski, R. and Segal, E.
Nature Medicine 28 (2): 295-302. February 2022

Alteration of gut microbiome in patients with schizophrenia indicates links between bacterial tyrosine biosynthesis and cognitive dysfunction.
Thirion, F. and Speyer, H. and Hansen, T.H. and Nielsen, T. and Fan, Y. and Le Chatelier, E. and Fromentin, S. and Berland, M. and Oñate, F.P. and Pons, N. and Galleron, N. and Levenez, F. and Marko, L. and Birkner, T. and Jørgensen, T. and Forslund, S.K. and Vestergaard, H. and Hansen, T. and Nordentoft, M. and Mors, O. and Benros, M.E. and Pedersen, O. and Ehrlich, S.D.
Biological Psychiatry Global Open Science 10 February 2022 (In Press)

4-phenylbutyrate restores localization and membrane repair to human dysferlin mutations.
Tominaga, K. and Tominaga, N. and Williams, E.O. and Rufibach, L. and Schöwel, V. and Spuler, S. and Viswanathan, M. and Guarente, L.P.
iScience 25 (1): 103667. 21 January 2022

S100A4 is a strong negative prognostic marker and potential therapeutic target in adenocarcinoma of the stomach and esophagus.
Treese, C. and Hartl, K. and Pötzsch, M. and Dahlmann, M. and von Winterfeld, M. and Berg, E. and Hummel, M. and Timm, L. and Rau, B. and Walther, W. and Daum, S. and Kobelt, D. and Stein, U.
Cells 11 (6): 1056. 21 March 2022

Inhibition of MACC1-induced metastasis in esophageal and gastric adenocarcinomas.
Treese, C. and Werchan, J. and von Winterfeld, M. and Berg, E. and Hummel, M. and Timm, L. and Rau, B. and Daberkow, O. and Walther, W. and Daum, S. and Kobelt, D. and Stein, U.
Cancers 14 (7): 1773. 31 March 2022

Tolerance induction through non-avoidance to prevent persistent food allergy (TINA) in children and adults with peanut or tree nut allergy: rationale, study design and methods of a randomized controlled trial and observational cohort study.
Trendelenburg, V. and Dölle-Bierke, S. and Unterleider, N. and Alexiou, A. and Kalb, B. and Meixner, L. and Heller, S. and Lau, S. and Lee, Y.A. and Fauchère, F. and Braun, J. and Babina, M. and Altrichter, S. and Birkner, T. and Roll, S. and Dobbertin-Welsch, J. and Worm, M. and Beyer, K.
Trials 23 (1): 236. 28 March 2022

None fits all: unraveling structural rearrangements of the CFH gene cluster in aHUS patients using molecular combing and long fragment targeted sequencing.
Tschernoster, N. and Erger, F. and Walsh, P.R. and McNicholas, B. and Fistrek, M. and Habbig, S. and Schumacher, L. and Folz-Donahue, K. and Kukat, C. and Toliat, M.R. and Becker, C. and Thiele, H. and Kavanagh, D. and Nürnberg, P. and Beck, B. and Altmüller, J.
Journal of Molecular Diagnostics 8 April 2022 (In Press)

Efficacy and safety of masitinib in progressive forms of multiple sclerosis: a randomized, phase 3, clinical trial.
Vermersch, P. and Brieva-Ruiz, L. and Fox, R.J. and Paul, F. and Ramio-Torrenta, L. and Schwab, M. and Moussy, A. and Mansfield, C. and Hermine, O. and Maciejowski, M.
Neurology Neuroimmunology & Neuroinflammation 9 (3): e1148. May 2022

Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H. and Dauksaite, V. and Sporbert, A. and Gotthardt, M. and Selbach, M.
Molecular Cell 14 April 2022 (In Press)

Elevated MACC1 expression in colorectal cancer is driven by chromosomal instability and is associated with molecular subtype and worse patient survival.
Vuaroqueaux, V. and Musch, A. and Kobelt, D. and Risch, T: and Herrmann, P. and Burock, S. and Peille, A.L. and Yaspo, M.L. and Fiebig, H.H. and Stein, U.
Cancers 14 (7): 1749. 1 April 2022

Disruptors of AKAP-dependent protein-protein interactions.
Walker-Gray, R. and Pallien, T. and Miller, D.C. and Oder, A. and Neuenschwander, M. and von Kries, J.P. and Diecke, S. and Klussmann, E.
Methods in Molecular Biology 2483 : 117-139. 2022

Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay.
Wallmeroth, D. and Lackmann, J.W. and Kueckelmann, S. and Altmüller, J. and Dieterich, C. and Boehm, V. and Gehring, N.H.
EMBO Journal 41 (10): e109191. 16 May 2022

Gating choreography and mechanism of the human proton-activated chloride channel ASOR.
Wang, C. and Polovitskaya, M.M. and Delgado, B.D. and Jentsch, T.J. and Long, S.B.
Science Advances 8 (5): eabm3942. 2 February 2022

Diagnostic efficacy of the magnetic resonance T1w/T2w ratio for the middle cerebellar peduncle in multiple system atrophy and spinocerebellar ataxia: a preliminary study.
Wang, J. and Sugiyama, A. and Yokota, H. and Hirano, S. and Cooper, G. and Mukai, H. and Ohira, K. and Koide, K. and Ito, S. and Finke, C. and Brandt, A.U. and Paul, F. and Kuwabara, S.
PLoS ONE 17 (4): e0267024. 15 April 2022

Venn diagrams may indicate erroneous statistical reasoning in transcriptomics.
Weiner, J. and Obermayer, B. and Beule, D.
Frontiers in Genetics 13 : 818683. 14 April 2022

A neutralizing IL-11 antibody improves renal function and increases lifespan in a mouse model of alport syndrome.
Widjaja, A.A. and Shekeran, S. and Adami, E. and Goh, J. and Tan, J. and Viswanathan, S. and Lim, S.Y. and Tan, P.H. and Hübner, N. and Coffman, T. and Cook, S.
Journal of the American Society of Nephrology 33 (4): 718-730. April 2022

Can fractal dimensions objectivize gastropod shell morphometrics? A case study from Lake Lugu (SW China).
Wiese, R. and Harrington, K. and Hartmann, K. and Hethke, M. and Rintelen, T. and Zhang, H. and Zhang, L.J. and Riedel, F.
Ecology and Evolution 12 (3): e8622. February 2022

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C. and Doebele, C. and Zindel, A. and Lee, K.S. and Rieke, S.A. and Ceribelli, M. and Comoglio, F. and Phelan, J.D. and Wang, J.Q. and Pikman, Y. and Jahn, D. and Häupl, B. and Schneider, C. and Scheich, S. and Tosto, F.A. and Bohnenberger, H. and Stauder, P. and Schnütgen, F. and Slabicki, M. and Coulibaly, Z.A. and Wolf, S. and Bojarczuk, K. and Chapuy, B. and Brandts, C.H. and Stroebel, P. and Lewis, C.A. and Engelke, M. and Xu, X. and Kim, H. and Dang, T.H. and Schmitz, R. and Hodson, D.J. and Stegmaier, K. and Urlaub, H. and Serve, H. and Schmitt, C.A. and Kreuz, F. and Knittel, G. and Rabinowitz, J.D. and Reinhardt, H.C. and Vander Heiden, M.G. and Thomas, C. and Staudt, L.M. and Zenz, T. and Oellerich, T.
Blood 139 (4): 538-553. 27 January 2022

Network meta-analysis of food and drug administration-approved treatment options for adults with aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorder.
Wingerchuk, D.M. and Zhang, I. and Kielhorn, A. and Royston, M. and Levy, M. and Fujihara, K. and Nakashima, I. and Tanvir, I. and Paul, F. and Pittock, S.J.
Neurology and Therapy 11 (1): 123-135. March 2022

Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single cell transcriptomics.
Wyler, E. and Adler, J.M. and Eschke, K. and Teixeira Alves, G. and Peidli, S. and Pott, F. and Kazmierski, J. and Michalick, L. and Kershaw, O. and Bushe, J. and Andreotti, S. and Pennitz, P. and Abdelgawad, A. and Postmus, D. and Goffinet, C. and Kreye, J. and Reincke, S.M. and Prüss, H. and Blüthgen, N. and Gruber, A.D. and Kuebler, W.M. and Witzenrath, M. and Landthaler, M. and Nouailles, G. and Trimpert, J.
Molecular Therapy 30 (5): 1952-1965. 4 May 2022

Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells.
Yang, M. and Yu, H. and Yu, X. and Liang, S. and Hu, Y. and Luo, Y. and Izsvák, Z. and Sun, C. and Wang, J.
Cell Stem Cell 29 (3): 400-418.e13. 3 March 2022

Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state.
Yigit, G. and Sheffer, R. and Daana, M. and Li, Y. and Kaygusuz, E. and Mor-Shakad, H. and Altmüller, J. and Nürnberg, P. and Douiev, L. and Kaulfuss, S. and Burfeind, P. and Wollnik, B. and Brockmann, K.
Journal of Medical Genetics 59 (6): 549-553. 20 May 2022

The host peritoneal cavity harbors prominent memory Th2 and early recall responses to an intestinal nematode.
Yordanova, I.A. and Jürchott, K. and Steinfelder, S. and Vogt, K. and Krüger, U. and Kühl, A.A. and Sawitzki, B. and Hartmann, S.
Frontiers in Immunology 13 : 842870. 28 March 2022

Tph2 gene expression defines ethanol drinking behavior in mice.
Zaniewska, M. and Mosienko, V. and Bader, M. and Alenina, N.
Cells 11 (5): 874. 3 March 2022

Proton-gated anion transport governs macropinosome shrinkage.
Zeziulia, M. and Blin, S. and Schmitt, F.W. and Lehmann, M. and Jentsch, T.J.
Nature Cell Biology 19 May 2022 (In Press)

RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis.
Zhang, Y. and Wang, C. and Sun, M. and Jin, Y. and Braz, C.U. and Khatib, H. and Hacker, T.A. and Liss, M. and Gotthardt, M. and Granzier, H. and Ge, Y. and Guo, W.
FASEB Journal 36 (5): e22302. May 2022

Role of TRPC6 in kidney damage after acute ischemic kidney injury.
Zheng, Z. and Tsvetkov, D. and Bartolomaeus, T.U.P. and Erdogan, C. and Krügel, U. and Schleifenbaum, J. and Schaefer, M. and Nürnberg, B. and Chai, X. and Ludwig, F.A. and N'diaye, G. and Köhler, M.B. and Wu, K. and Gollasch, M. and Markó, L.
Scientific Reports 12 (1): 3038. 22 February 2022

Autophagy takes it all - autophagy inducers target immune aging.
Zinecker, H. and Simon, A.K.
Disease Models & Mechanisms 15 (1): dmm049345. 31 January 2022

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U. and Milek, M. and Minia, I. and Vieira-Vieira, C.H. and Müller, S. and Mastrobuoni, G. and Hazapis, O.G. and Del Giudice, S. and Schwefel, D. and Bley, N. and Voigt, F. and Chao, J.A. and Kempa, S. and Hüttelmaier, S. and Selbach, M. and Landthaler, M.
Nature Communications 13 (1): 2727. 18 May 2022

Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling law.
Zou, X. and Schaefke, B. and Li, Y. and Jia, F. and Sun, W. and Li, G. and Liang, W. and Reif, T. and Heyd, F. and Gao, Q. and Tian, S. and Li, Y. and Tang, Y. and Fang, L. and Hu, Y. and Chen, W.
Life Science Alliance 5 (4): e202101333. April 2022

Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction.
Zywitza, V. and Rusha, E. and Shaposhnikov, D. and Ruiz-Orera, J. and Telugu, N. and Rishko, V. and Hayashi, M. and Michel, G. and Wittler, L. and Stejskal, J. and Holtze, S. and Göritz, F. and Hermes, R. and Wang, J. and Izsvák, Z. and Colleoni, S. and Lazzari, G. and Galli, C. and Hildebrandt, T.B. and Hayashi, K. and Diecke, S. and Drukker, M.
Scientific Reports 12 (1): 3100. 8 March 2022

Altered nuclear architecture in blood cells from Huntington's disease patients.
de Castro, I.J. and Toner, B. and Xie, S.Q. and Swingland, J. and Hodges, A. and Tabrizi, S.J. and Turkheimer, F. and Pombo, A. and Khalil, A.
Neurological Sciences 43 (1): 379-385. January 2022

SMOG 2 and OpenSMOG: extending the limits of structure-based models.
de Oliveira, A.B. and Contessoto, V.G. and Hassan, A. and Byju, S. and Wang, A. and Wang, Y. and Dodero-Rojas, E. and Mohanty, U. and Noel, J.K. and Onuchic, J.N. and Whitford, P.C.
Protein Science 31 (1): 158-172. January 2022

The genomic and spatial mobility of extrachromosomal DNA and its implications for cancer therapy.
van Leen, E. and Brückner, L. and Henssen, A.G.
Nature Genetics 54 (2): 107-114. February 2022

State-dependent signatures of anti-N-methyl-d-aspartate receptor encephalitis.
von Schwanenflug, N. and Krohn, S. and Heine, J. and Paul, F. and Prüss, H. and Finke, C.
Brain Communications 4 (1): fcab298. 1 February 2022

Book Section

Salt, aldosterone, and the renin-angiotensin system in pregnancy.
Dechend, R. and Lamarca, B. and Davidge, S.T.
In: Chesley's Hypertensive Disorders in Pregnancy. Elsevier / Academic Press, 335-353. ISBN 978-0-12-818417-2 2022

Conference or Workshop Item

Fusion moves for graph matching.
Hutschenreiter, L. and Haller, S. and Feineis, L. and Rother, C. and Kainmüller, D. and Savchynskyy, B.
In: 2021 IEEE/CVF International Conference on Computer Vision (ICCV), 10-17 Oct 2021, Montreal, QC, Canada. 28 February 2022

How shift equivariance impacts metric learning for instance segmentation.
Rumberger, J.L. and Yu, X. and Hirsch, P. and Dohmen, M. and Guarino, V.E. and Mokarian, A. and Mais, L. and Funke, J. and Kainmueller, D.
In: 2021 IEEE/CVF International Conference on Computer Vision (ICCV), 10-17 Oct 2021, Montreal, QC, Canada. 28 February 2022

Review

Management of malignant dysgerminoma of the ovary.
Arndt, T. and Taube, E.T. and Deubzer, H.E. and Rothe, K. and Calaminus, G. and Sehouli, J. and Pietzner, K.
European Journal of Gynaecological Oncology 43 (2): 353-362. 15 April 2022

Tissue engineering for the diaphragm and its various therapeutic possibilities - a systematic review.
Boehm, A.K. and Hillebrandt, K.H. and Dziodzio, T. and Krenzien, F. and Neudecker, J. and Spuler, S. and Pratschke, J. and Sauer, I.M. and Andreas, M.N.
Advanced Therapeutics : 2100247. 4 April 2022 (In Press)

Oxidative RNA damage in the pathogenesis and treatment of type 2 diabetes.
Chen, X. and Yu, H. and Li, Z. and Ye, W. and Liu, Z. and Gao, J. and Wang, Y. and Li, X. and Zhang, L. and Alenina, N. and Bader, M. and Ding, H. and Li, P. and Aung, L.H.H.
Frontiers in Physiology 13 : 725919. 28 March 2022

Physical mechanisms of chromatin spatial organization.
Chiariello, A.M. and Bianco, S. and Esposito, A. and Fiorillo, L. and Conte, M. and Irani, E. and Musella, F. and Abraham, A. and Prisco, A. and Nicodemi, M.
FEBS Journal 289 (5): 1180-1190. March 2022

Personalisierte Medizin in der Kinderonkologie: Wo stehen wir heute?
Deubzer, H.E. and Schulte, J.H. and Eggert, A.
TumorDiagnostik & Therapie 43 (01): 29-44. February 2022

Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies.
Frantz, S. and Hundertmark, M.J. and Schulz-Menger, J. and Bengel, F.M. and Bauersachs, J.
European Heart Journal : ehac223. 4 May 2022 (In Press)

Cosmeceutical potential of major tropical and subtropical fruit by-products for a sustainable revalorization.
García-Villegas, A. and Rojas-García, A. and Villegas-Aguilar, M.C. and Fernández-Moreno, P. and Fernández-Ochoa, Á. and Cádiz-Gurrea, M.L. and Arráez-Román, D. and Segura-Carretero, A.
Antioxidants 11 (2): 203. 21 January 2022

Leveraging visual outcome measures to advance therapy development in neuroimmunologic disorders.
Graves, J.S. and Oertel, F.C. and Van der Walt, A. and Collorone, S. and Sotirchos, E.S. and Pihl-Jensen, G. and Albrecht, P. and Yeh, E.A. and Saidha, S. and Frederiksen, J. and Newsome, S.D. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 9 (2): e1126. March 2022

Refining AML treatment: the role of genetics in response and resistance evaluation to new agents.
Halik, A. and Arends, C.M. and Bullinger, L. and Damm, F. and Frick, M.
Cancers 14 (7): 1689. 26 March 2022

The gut microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS).
König, R.S. and Albrich, W.C. and Kahlert, C.R. and Bahr, L.S. and Löber, U. and Vernazza, P. and Scheibenbogen, C. and Forslund, S.K.
Frontiers in Immunology 12 : 628741. 3 January 2022

Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D. and Oshima, M. and Stange, D.E. and Sigal, M.
Gastroenterology 162 (4): 1067-1087. April 2022

Regulation of early cerebellar development.
Lowenstein, E. and Cui, K. and Hernandez-Miranda, L.R.
FEBS Journal 9 March 2022 (In Press)

Physiological functions of intracellular protein degradation.
McShane, E. and Selbach, M.
Annual Review of Cell and Developmental Biology 19 May 2022 (In Press)

The genetic basis of Moyamoya disease.
Mertens, R. and Graupera, M. and Gerhardt, H. and Bersano, A. and Tournier-Lasserve, E. and Mensah, M.A. and Mundlos, S. and Vajkoczy, P.
Translational Stroke Research 13 (1): 25-45. February 2022

Formation and maintenance of the natural bypass vessels of the brain.
Perovic, T. and Harms, C. and Gerhardt, H.
Frontiers in Cardiovascular Medicine 9 : 778773. 22 March 2022

Neuroligins in neurodevelopmental conditions: how mouse models of de novo mutations can help us link synaptic function to social behavior.
Pohl, T. and Hörnberg, H.
Neuronal Signaling 6 (2): NS20210030. June 2022

The role of CD4 T cells in rejection of solid tumors.
Poncette, L. and Bluhm, J. and Blankenstein, T.
Current Opinion in Immunology 74 : 18-24. February 2022

Sustainable low-field cardiovascular magnetic resonance in changing healthcare systems.
Qin, C. and Murali, S. and Lee, E. and Supramaniam, V. and Hausenloy, D.J. and Obungoloch, J. and Brecher, J. and Lin, R. and Ding, H. and Akudjedu, T.N. and Anazodo, U.C. and Jagannathan, N.R. and Ntusi, N.A.B. and Simonetti, O.P. and Campbell-Washburn, A.E. and Niendorf, T. and Mammen, R. and Adeleke, S.
European Heart Journal - Cardiovascular Imaging : jeab286. 14 February 2022

Intricacies of single-cell multi-omics data integration.
Rautenstrauch, P. and Vlot, A.H.C. and Saran, S. and Ohler, U.
Trends in Genetics 38 (2): 128-139. February 2022

Immunometabolic mechanisms of heart failure with preserved ejection fraction.
Schiattarella, G.G. and Alcaide, P. and Condorelli, G. and Gillette, T.G. and Heymans, S. and Jones, E.A.V. and Kallikourdis, M. and Lichtman, A. and Marelli-Berg, F. and Shah, S.J. and Thorp, E.B. and Hill, J.A.
Nature Cardiovascular Research 1 (3): 211-222. March 2022

Tailoring cardiac synthetic transcriptional modulation towards precision medicine.
Schoger, E. and Lelek, S. and Panáková, D. and Zelarayán, L.C.
Frontiers in Cardiovascular Medicine 8 : 783072. 14 January 2022

Microcircuits for spatial coding in the medial entorhinal cortex.
Tukker, J.J. and Beed, P. and Brecht, M. and Kempter, R. and Moser, E.I. and Schmitz, D.
Physiological Reviews 102 (2): 653-688. 1 April 2022

Novel targets, treatments, and advanced models for intracerebral haemorrhage.
Zille, M. and Farr, T.D. and Keep, R.F. and Römer, C. and Xi, G. and Boltze, J.
EBioMedicine 76 : 103880. 12 February 2022

Therapeutic targets for phenolic compounds from agro-industrial by-products against obesity.
de la Luz Cádiz-Gurrea, M. and Fernández-Ochoa, Á. and Del Carmen Villegas-Aguilar, M. and Arráez-Román, D. and Segura-Carretero, A.
Current Medicinal Chemistry 29 (6): 1083-1098. 2022

Letter

Determinants of expression of SARS-CoV-2 entry related genes in upper and lower airways.
Aliee, H. and Massip, F. and Qi, C. and de Biase, M.S. and van Nijnatten, J. and Kersten, E.T.G. and Kermani, N.Z. and Khuder, B. and Vonk, J.M. and Vermeulen, R.C.H. and Neighbors, M. and Tew, G.W. and Grimbaldeston, M.A. and Ten Hacken, N.H.T. and Hu, S. and Guo, Y. and Zhang, X. and Sun, K. and Hiemstra, P.S. and Ponder, B.A. and Mäkelä, M.J. and Malmström, K. and Rintoul, R.C. and Reyfman, P.A. and Theis, F.J. and Brandsma, C.A. and Adcock, I.M. and Timens, W. and Xu, C.J. and van den Berge, M. and Schwarz, R.F. and Koppelman, G.H. and Nawijn, M.C. and Faiz, A.
Allergy 77 (2): 690-694. February 2022

Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M. and Dimitriou, S. and Stahler, A. and Hablesreiter, R. and Strzelecka, P.M. and Stein, C.M. and Tilgner, M. and Saiki, R. and Ogawa, S. and Bullinger, L. and Modest, D.P. and Stintzing, S. and Heinemann, V. and Damm, F.
Blood 139 (10): 1593-1597. 10 March 2022

Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group.
Damaschin, C. and Goergen, H. and Kreissl, S. and Plütschow, A. and Breywisch, F. and Mathas, S. and Meissner, J. and Sökler, M. and Topp, M.S. and Vucinic, V. and Zimmermann, A. and von Tresckow, B. and Fuchs, M. and Engert, A. and Borchmann, P. and Eichenauer, D.A.
Leukemia 36 (2): 580-582. February 2022

Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O. and Zincke, F. and Eckert, A. and Kobelt, D. and Preissner, S. and Liebeskind, J.M. and Gunkel, N. and Putzker, K. and Lewis, J. and Preissner, S. and Kortüm, B. and Walther, W. and Mura, K. and Bourne, P.E. and Stein, U. and Preissner, R.
Clinical and Translational Medicine 12 (2): e726. 20 February 2022

Effect of sunitinib treatment on skin sodium accumulation in patients with renal cancer: a pilot study.
Marko, L. and Dörr, A. and Linz, P. and van den Meiracker, A.H. and Garrelds, I.M. and Kuehne, T. and Dechend, R. and Danser, A.H.J. and Flörcken, A. and Müller, D.N.
Hypertension 79 (5): e103-e105. May 2022

Severe heart failure in the setting of inflammatory cardiomyopathy with likely pathogenic titin variant.
Mueller, M. and Zwinger, L. and Klaassen, S. and Poller, W. and Monserrat Iglesias, L. and Pablo Ochoa, J. and Klingel, K. and Landmesser, U. and Heidecker, B.
International Journal of Cardiology (IJC) Heart & Vasculature 39 : 100969. April 2022

A peculiar case of primary central nervous system T-cell lymphoma with indolent behavior.
Wasilewski, D. and Janz, M. and Koch, A. and Rosenwald, A. and Keller, U. and Vajkoczy, P. and Faust, K. and Anagnostopoulos, I. and Radke, J.
Acta Neurologica Belgica 2 April 2022 (In Press)

Editorial

In memoriam: Stephen B. McMahon, PhD, FMedSci December 21, 1954 to October 9, 2021.
Bennett, D.L.H. and Bradbury, E.J. and Lewin, G.R. and Rice, A.S.C.
Pain 163 (3): 403-405. March 2022

CEBPA mutations in AML: site matters.
Bullinger, L.
Blood 139 (1): 6-7. 6 January 2022

The blood-brain barrier-a metabolic ecosystem.
Castro, M. and Potente, M.
EMBO Journal 41 (9): e111189. 2 May 2022

SPFH protein cage - one ring to rule them all.
Daumke, O. and Lewin, G.R.
Cell Research 32 (2): 117-118. February 2022

Stellenwert der kardiovaskulären Magnetresonanz in der kardiovaskulären Diagnostik [Role of cardiovascular magnetic resonance in cardiovascular diagnostics].
Gröschel, J. and Trauzeddel, R.F. and Blaszczyk, E. and Schulz-Menger, J.
Deutsche Medizinische Wochenschrift 147 (9): 528-537. 25 April 2022

Shedding light on ecDNA behavior using CRISPR-based live-cell imaging.
Henssen, A.G.
Cancer Discovery 12 (2): 293-295. 9 February 2022

Time for change in research careers: Are we as research organizations doing everything we can for postdocs?
Krull, S. and Silva, A.A. and Afanasyeva, D. and Christensen, S. and Agostinho, M.
EMBO Reports 23 (2): e54260. 3 February 2022

Translating plasma sodium, stores, and hydration state from mouse to man.
Luft, F.C.
European Heart Journal 7 April 2022 (In Press)

Amiloride and calciuria.
Luft, F.C. and Sällström, J.
Nephrology Dialysis Transplantation 37 (2): 205-207. February 2022

ATACing single cells with phages.
Maschmeyer, P. and Haas, S.
Molecular Cell 82 (2): 234-236. 20 January 2022

Time-keeping and decision-making in living cells: Part I.
Tyson, J.J. and Csikasz-Nagy, A. and Gonze, D. and Kim, J.K. and Santos, S. and Wolf, J.
Interface Focus 12 (3): 20220011. 6 June 2022

GABAergic interneurons with nonlinear dendrites: from neuronal computations to memory engrams.
Tzilivaki, A. and Kastellakis, G. and Schmitz, D. and Poirazi, P.
Neuroscience 489 : 34-43. 1 May 2022

Comment

Cancer stem cells: The adventurous journey from hematopoietic to leukemic stem cells.
Trumpp, A. and Haas, S.
Cell 185 (8): 1266-1270. 14 April 2022

Preprint

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M. and Grishkovskaya, I. and Benedum, J. and Franke, V. and Polyansky, A. and Neudolt, A. and Wunder, A. and Zagrovic, B. and Akalin, A. and Djinovic-Carugo, K. and Slade, D.
bioRxiv : 2022.02.26.482114. 27 February 2022

PyZebraScope: an open-source platform for brain-wide neural activity imaging in zebrafish.
Barbara, R. and Kantharaju, M.N. and Haruvi, R. and Harrington, K. and Kawashima, T.
bioRxiv : bioRxiv. 15 February 2022

Global analysis of human-to-mouse contact-dependent intercellular mRNA and lncRNA transfer in cell culture.
Dasgupta, Sandipan and Dyagi, Daniella Y. and Haimovich, Gal and Wyler, E. and Olender, Tsviya and Singer, Robert H. and Landthaler, M. and Gerst, Jeffrey E
bioRxiv : 2021.11.28.470233v2. 7 March 2022

One gene - two proteins: the C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria.
Fasciani, I. and Petragnano, F. and Wang, Z. and Edwards, R. and Telugu, N. and Pietrantoni, I. and Zauber, H. and Rossi, M. and Zabel, U. and Grieben, M. and Terzenidou, M.E. and Di Gregorio, J. and Pellegrini, C. and Santini, S. and Taddei, A.R. and Poehl, B. and Aringhieri, S. and Aloisi, G. and Marampon, F. and Roman, A. and Diecke, S. and Flati, V. and Giorgi, F. and Amicarelli, F. and Tobin, A.B. and Scarselli, M. and Tokatlidis, K. and Lohse, M.J. and Maggio, R. and Annibale, P.
bioRxiv : 2021.04.13.438299. 26 February 2022

C. difficile is overdiagnosed in adults and a commensal in infants.
Ferretti, P. and Wirbel, J. and Maistrenko, O.M. and Van Rossum, T. and Alves, R. and Fullam, A. and Akanni, W. and Schudoma, C. and Schwarz, A. and Thielemann, R. and Thomas, L. and Kuhn, M. and Zeller, G. and Schmidt, T.S.B. and Bork, P.
bioRxiv : 2022.02.16.480740v1. 18 February 2022

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development.
Freitag, K. and Eede, P. and Ivanov, A. and Schneeberger, S. and Borodina, T. and Sauer, S. and Beule, D. and Heppner, F.
Research Square : rs.3.rs-1362379/v1. 28 February 2022

Prostate megalin is regulated by serum hormone levels and imports globulin-bound testosterone.
Garcia, J. and Krieger, K. and Loitz, C. and Perez, L.M. and Richards, Z.A. and Helou, Y.B. and Kregel, S. and Selada, S. and Mesaros, C.A. and Gann, P. and Willnow, T.E. and Vander Griend, D. and Kittles, R. and Prins, G. and Penning, T. and Nonn, L.
bioRxiv : 2021.11.09.467567. 27 February 2022

Epstein-Barr virus-driven B cell lymphoma mediated by a unique LMP1-TRAF6 complex.
Giehler, F. and Ostertag, M. and Sommermann, T. and Weidl, D. and Sterz, K. and Kutz, H. and Feller, S. and Geerlof, A. and Biesinger, B. and Popowicz, G. and Kirchmair, J. and Kieser, A.
Research Square : rs.3.rs-1295699/v1. 4 February 2022

Aging-regulated TUG1 is dispensable for endothelial cell function.
Gimbel, A.T. and Koziarek, S. and Theodorou, K. and Schulz, J.F. and Stanicek, L. and Ali, T. and Günther, S. and Kumar, S. and Jo, H. and Hübner, N. and Maegdefessel, L. and Dimmeler, S. and van Heesch, S. and Boon, R.A.
bioRxiv : 2022.02.27.482212. 28 February 2022

Spatio-temporal, optogenetic control of gene expression in organoids.
Legnini, I. and Emmenegger, L. and Zappulo, A. and Wurmus, R. and Oliveras Martinez, A. and Cerda Jara, C. and Boltengagen, A. and Hessler, T. and Mastrobuoni, G. and Rybak-Wolf, A. and Kempa, S. and Zinzen, R.P. and Woehler, A. and Rajewsky, N.
bioRxiv : 2021.09.26.461850v3. 9 February 2022

The little skate genome and the evolutionary emergence of wing-like fin appendages.
Marletaz, F. and de la Calle-Mustienes, E. and Acemel, R.D. and Nakamura, T. and Paliou, C. and Naranjo, S. and Martinez-Garcia, P.M. and Cases, I. and Sleight, V.A. and Hirschberger, C. and Marcet-Houben, M. and Navon, D. and Andrescavage, A. and Skvortsova, K. and Duckett, P.E. and Gonzalez-Rajal, A. and Bogdanovic, O. and Gibcus, J.H. and Yang, L. and Gallardo-Fuentes, L. and Sospedra, I. and Lopez-Rios, J. and Darbellay, F. and Visel, A. and Dekker, J. and Shubin, N. and Gabaldon, T. and Tena, J.J. and Lupianez, D.G. and Rokhsar, D.S. and Gomez-Skarmeta, J.L.
bioRxiv : 2022.03.21.485123. 22 March 2022

Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.
Monti, R. and Rautenstrauch, P. and Ghanbari, M. and James, A.R. and Ohler, U. and Konigorski, S. and Lippert, C.
bioRxiv : 2021.05.27.444972. 20 January 2022

The molecular mechanism and physiological role of silent nociceptor activation.
Nees, T.A. and Wang, N. and Adamek, P. and Verkest, C. and Schaefer, I. and Virnich, J. and Balkaya, S. and Prato, V. and Morelli, C. and Zeitzschel, N. and Begay, V. and Lee, Y.J. and Lewin, G.R. and Heppenstall, P.A. and Taberner, F.J. and Lechner, S.G.
bioRxiv : 2022.04.07.486730. 10 April 2022

Panoptic segmentation with highly imbalanced semantic labels.
Rumberger, J.L. and Baumann, E. and Hirsch, P. and Janowczyk, A. and Zlobec, I. and Kainmueller, D.
arXiv : 2203.11692. 19 April 2022

A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ cells to diabetes recovery in zebrafish.
Singh, S.P. and Chawla, P. and Hnatiuk, A. and Kamel, M. and Silva, L.D. and Spanjard, B. and Eski, S.E. and Janjuha, S. and Olivares, P. and Kayisoglu, O. and Rost, F. and Bläsche, J. and Kränkel, A. and Petzold, A. and Kurth, T. and Reinhardt, S. and Junker, J.P. and Ninov, N.
bioRxiv : 2021.06.24.449704. 31 January 2022

This list was generated on Sat May 28 02:12:12 2022 CEST.
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