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Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.
Abdelhak, A. and Cordano, C. and Boscardin, W.J. and Caverzasi, E. and Kuhle, J. and Chan, B. and Gelfand, J.M. and Yiu, H.H. and Oertel, F.C. and Beaudry-Richard, A. and Condor Montes, S. and Oksenberg, J.R. and Lario Lago, A. and Boxer, A. and Rojas-Martinez, J.C. and Elahi, F.M. and Chan, J.R. and Green, A.J.
Journal of Neurology Neurosurgery and Psychiatry 93 (9): 972-977. 12 August 2022

Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.
Abdelhak, A. and Solomon, I. and Montes, S.C. and Saias, A. and Cordano, C. and Asken, B. and Fonseca, C. and Oertel, F.C. and Arfanakis, K. and Staffaroni, A.M. and Kramer, J.H. and Geschwind, M. and Miller, B.L. and Elahi, F.M. and Green, A.J.
Alzheimer's & Dementia: Diagnosis Assessment & Disease Monitoring 14 (1): e12338. 2022

HDHL-INTIMIC: a European knowledge platform on food, diet, intestinal microbiomics, and human health.
Agamennone, V. and Abuja, P.M. and Basic, M. and De Angelis, M. and Gessner, A. and Keijser, B. and Larsen, M. and Pinart, M. and Nimptsch, K. and Pujos-Guillot, E. and Schlicht, K. and Sharon, I. and Untersmayr, E. and Laudes, M. and Pischon, T. and Bouwman, J.
Nutrients 14 (9): 1881. 29 April 2022

A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4(+) T cells and is defective in Crohn's disease patients.
Ahlers, J. and Mantei, A. and Lozza, L. and Stäber, M. and Heinrich, F. and Bacher, P. and Hohnstein, T. and Menzel, L. and Yüz, S.G. and Alvarez-Simon, D. and Bickenbach, A.R. and Weidinger, C. and Mockel-Tenbrinck, N. and Kühl, A.A. and Siegmund, B. and Maul, J. and Neumann, C. and Scheffold, A.
Mucosal Immunology 15 (3): 480-490. May 2022

Midwall fibrosis and cardiac mechanics: rigid body rotation is a novel marker of disease severity in pediatric primary dilated cardiomyopathy.
Al-Wakeel-Marquard, N. and Seidel, F. and Kühnisch, J. and Kuehne, T. and Berger, F. and Messroghli, D.R. and Klaassen, S.
Frontiers in Cardiovascular Medicine 8 : 810005. 17 February 2022

Angiotensin 1-7 increases fiber cross sectional area and force in juvenile mouse skeletal muscle.
Albadrani, H. and Ammar, T. and Rajgara, R. and Bader, M. and Wiper-Bergeron, N. and Renaud, J.M.
American Journal of Physiology Cell Physiology 323 (6): C1681-C1696. December 2022

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H. and Flórez, A.F. and Kreth, S. and Brückner, L.M. and Yildiz, U. and Gartlgruber, M. and Odoni, D.I. and Poschet, G. and Garbowicz, K. and Shao, C. and Klein, C. and Meier, J. and Zeisberger, P. and Nadler-Holly, M. and Ziehm, M. and Paul, F. and Burhenne, J. and Bell, E. and Shaikhkarami, M. and Würth, R. and Stainczyk, S.A. and Wecht, E.M. and Kreth, J. and Büttner, M. and Ishaque, N. and Schlesner, M. and Nicke, B. and Stresemann, C. and Llamazares-Prada, M. and Reiling, J.H. and Fischer, M. and Amit, I. and Selbach, M. and Herrmann, C. and Wölfl, S. and Henrich, K.O. and Höfer, T. and Trumpp, A. and Westermann, F.
Nature Cancer 3 (4): 471-485. 28 April 2022

Lifting the veil of secrecy: maternal and neonatal outcome of oocyte donation pregnancies in Germany.
Altmann, J. and Kummer, J. and Herse, F. and Hellmeyer, L. and Schlembach, D. and Henrich, W. and Weichert, A.
Archives of Gynecology and Obstetrics 306 (1): 59-69. July 2022

Acute myocarditis associated with desmosomal gene variants.
Ammirati, E. and Raimondi, F. and Piriou, N. and Sardo Infirri, L. and Mohiddin, S.A. and Mazzanti, A. and Shenoy, C. and Cavallari, U.A. and Imazio, M. and Aquaro, G.D. and Olivotto, I. and Pedrotti, P. and Sekhri, N. and Van de Heyning, C.M. and Broeckx, G. and Peretto, G. and Guttmann, O. and Dellegrottaglie, S. and Scatteia, A. and Gentile, P. and Merlo, M. and Goldberg, R.I. and Reyentovich, A. and Sciamanna, C. and Klaassen, S. and Poller, W. and Trankle, C.R. and Abbate, A. and Keren, A. and Horowitz-Cederboim, S. and Cadrin-Tourigny, J. and Tadros, R. and Annoni, G.A. and Bonoldi, E. and Toquet, C. and Marteau, L. and Probst, V. and Trochu, J.N. and Kissopoulou, A. and Grosu, A. and Kukavica, D. and Trancuccio, A. and Gil, C. and Tini, G. and Pedrazzini, M. and Torchio, M. and Sinagra, G. and Gimeno, J.R. and Bernasconi, D. and Valsecchi, M.G. and Klingel, K. and Adler, E.D. and Camici, P.G. and Cooper, L.T.
JACC Heart Fail 10 (10): 714-727. October 2022

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C. and Acemel, R.D. and Jedamzick, J. and Bolondi, A. and Cova, G. and Brieske, N. and Kühn, R. and Wittler, L. and Real, F.M. and Lupiáñez, D.G.
Nature Genetics July 2022

Different impact of gadopentetate and gadobutrol on inflammation-promoted retention and toxicity of gadolinium within the mouse brain.
Anderhalten, L. and Silva, R.V. and Morr, A. and Wang, S. and Smorodchenko, A. and Saatz, J. and Traub, H. and Mueller, S. and Boehm-Sturm, P. and Rodriguez-Sillke, Y. and Kunkel, D. and Hahndorf, J. and Paul, F. and Taupitz, M. and Sack, I. and Infante-Duarte, C.
Investigative Radiology 57 (10): 677-688. 1 October 2022

De novo whole genome assembly of the Roborovski dwarf hamster (Phodopus roborovskii) genome, an animal model for severe/critical COVID-19.
Andreotti, S. and Altmüller, J. and Quedenau, C. and Borodina, T. and Nouailles, G. and Teixeira Alves, L.G. and Landthaler, M. and Bieniara, M. and Trimpert, J. and Wyler, E.
Genome Biology and Evolution 14 (7): evac100. July 2022

Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming.
Anh, L.P.H. and Nishimura, K. and Kuno, A. and Nguyen, T.L. and Kato, T. and Ohtaka, M. and Nakanishi, M. and Sugihara, E. and Sato, T.A. and Hayashi, Y. and Fukuda, A. and Hisatake, K.
Stem Cells 40 (4): 397-410. 29 April 2022

Integrative analysis of macrophage ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classes.
Ansari, S.A. and Dantoft, W. and Ruiz-Orera, J. and Syed, A.P. and Blachut, S. and van Heesch, S. and Hübner, N. and Uhlenhaut, N.H.
Computational and Structural Biotechnology Journal 20 : 5622-5638. 3 October 2022

Prognostic value of stress cardiac magnetic resonance in patients with known coronary artery disease.
Antiochos, P. and Ge, Y. and Heydari, B. and Steel, K. and Bingham, S. and Abdullah, S.M. and Mikolich, J.R. and Arai, A.E. and Bandettini, W.P. and Patel, A.R. and Farzaneh-Far, A. and Heitner, J.F. and Shenoy, C. and Leung, S.W. and Gonzalez, J.A. and Shah, D.J. and Raman, S.V. and Ferrari, V.A. and Schulz-Menger, J. and Stuber, M. and Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 15 (1): 60-71. January 2022

Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling.
Anton, S.E. and Kayser, C. and Maiellaro, I. and Nemec, K. and Möller, J. and Koschinski, A. and Zaccolo, M. and Annibale, P. and Falcke, M. and Lohse, M.J. and Bock, A.
Cell 185 (7): 1130-1142.e11. 31 March 2022

Carbon-mixed dental cement for fixing fiber optic ferrules prevents visually triggered locomotive enhancement in mice upon optogenetic stimulation.
Araragi, N. and Alenina, N. and Bader, M.
Heliyon 8 (1): e08692. January 2022

Immunohistochemical analysis of nicotinamide phosphoribosyltransferase expression in gastric and esophageal adenocarcinoma (AEG).
Arnold, A. and von Winterfeld, M. and Berg, E. and Hummel, M. and Rau, B. and Krenzien, F. and Stein, U. and Treese, C.
Gastrointestinal Disorders 4 (4): 333-340. 13 December 2022

Kinin B1 receptor modulates mitochondrial activity responsivity in fasting and voluntary exercise.
Arruda, A.C. and Budu, A. and de Menezes, T.N. and Bader, M. and Araujo, R.C. and Freitas-Lima, L.C.
Life Sciences 309 : 121034. 15 November 2022

LABKIT: labeling and segmentation toolkit for big image data.
Arzt, M. and Deschamps, J. and Schmied, C. and Pietzsch, T. and Schmidt, D. and Tomancak, P. and Haase, R. and Jug, F.
Frontiers in Computer Science 4 : 777728. 10 February 2022

De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway.
Asif, M. and Kaygusuz, E. and Shinawi, M. and Nickelsen, A. and Hsieh, T.C. and Wagle, P. and Budde, B. and Hochscherf, J. and Abdullah, U. and Höning, S. and Nienberg, C. and Lindenblatt, D. and Noegel, A.A. and Altmüller, J. and Thiele, H. and Motameny, S. and Fleischer, N. and Segal, I. and Pais, L. and Tinschert, S. and Samra, N.G. and Savatt, J.M. and Rudy, N.L. and De Luca, C. and Fortugno, P. and White, S.M. and Krawitz, P. and Hurst, A.C.E. and Niefind, K. and Jose, J. and Brancati, F. and Nürnberg, P. and Hussain, M.S.
Human Genetics and Genomics Advances 3 (3): 100111. 14 July 2022

A novel missense variant of SCN4A co-segregates with congenital essential tremor in a consanguineous Kurdish family.
Asif, M. and Mocanu, I.D. and Abdullah, U. and Höhne, W. and Altmüller, J. and Makhdoom, E.U.H. and Thiele, H. and Baig, S.M. and Nürnberg, P. and Graul-Neumann, L. and Hussain, M.S.
American Journal of Medical Genetics A 188 (4): 1251-1258. April 2022

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
Axelsson Raja, A. and Wakimoto, H. and DeLaughter, D.M. and Reichart, D. and Gorham, J. and Conner, D.A. and Lun, M. and Probst, C.K. and Sakai, N. and Knipe, R.S. and Montesi, S.B. and Shea, B. and Adam, L.P. and Leinwand, L.A. and Wan, W. and Choi, E.S. and Lindberg, E.L. and Patone, G. and Noseda, M. and Hübner, N. and Seidman, C.E. and Tager, A.M. and Seidman, J.G. and Ho, C.Y.
Proceedings of the National Academy of Sciences of the United States of America 119 (28): e2204174119. 12 July 2022

Impaired motion perception is associated with functional and structural visual pathway damage in multiple sclerosis and neuromyelitis optica spectrum disorders.
Ayadi, N. and Oertel, F.C. and Asseyer, S. and Rust, R. and Duchow, A. and Kuchling, J. and Bellmann-Strobl, J. and Ruprecht, K. and Klistorner, A. and Brandt, A.U. and Paul, F. and Zimmermann, H.G.
Multiple Sclerosis Journal 28 (5): 757-767. April 2022

Selective endocytosis of Ca(2+)-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.
Azarnia Tehran, D. and Kochlamazashvili, G. and Pampaloni, N. P. and Sposini, S. and Shergill, J.K. and Lehmann, M. and Pashkova, N. and Schmidt, C. and Löwe, D. and Napieczynska, H. and Heuser, A. and Plested, A.J.R. and Perrais, D. and Piper, R.C. and Haucke, V. and Maritzen, T.
Science Advances 8 (21): eabl5032. 27 May 2022

A naked eye-invisible ratiometric fluorescent microneedle tattoo for real-time monitoring of inflammatory skin conditions.
Babity, S. and Couture, F. and Campos, E.V.R. and Hedtrich, S. and Hagen, R. and Fehr, D. and Bonmarin, M. and Brambilla, D.
Advanced Healthcare Materials 11 (6): e2102070. March 2022

Anatomical and functional visual network patterns in progressive multiple sclerosis.
Backner, Y. and Zamir, S. and Petrou, P. and Paul, F. and Karussis, D. and Levin, N.
Human Brain Mapping 43 (5): 1590-1597. 1 April 2022

RS-FISH: precise, interactive, fast, and scalable FISH spot detection.
Bahry, E. and Breimann, L. and Zouinkhi, M. and Epstein, L. and Kolyvanov, K. and Mamrak, N. and King, B. and Long, Xi and Harrington, K.I.S. and Lionnet, T. and Preibisch, S.
Nature Methods 19 (12): 1563-1567. December 2022

Microglia form satellites with different neuronal subtypes in the adult murine central nervous system.
Bakina, O. and Kettenmann, H. and Nolte, C.
Journal of Neuroscience Research 100 (4): 1105-1122. April 2022

Unraveling the hidden temporal range of fast β(2)-adrenergic receptor mobility by time-resolved fluorescence.
Balakrishnan, A. and Hemmen, K. and Choudhury, S. and Krohn, J.H. and Jansen, K. and Friedrich, M. and Beliu, G. and Sauer, M. and Lohse, M.J. and Heinze, K.G.
Communications Biology 5 (1): 176. 28 February 2022

Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S. and Andreani, M. and Goncalves Andrade, J. and Saha, T. and Sundaravinayagam, D. and Garzón, J. and Zhang, W. and Popp, O. and Hiraga, S. and Rahjouei, A. and Rosen, D.B. and Mertins, P. and Chait, B.T. and Donaldson, A.D. and Di Virgilio, M.
eLife 11 : e75047. 13 April 2022

Aurora kinase A is involved in controlling the localization of aquaporin-2 in renal principal cells.
Baltzer, S. and Bulatov, T. and Schmied, C. and Krämer, A. and Berger, B.T. and Oder, A. and Walker-Gray, R. and Kuschke, C. and Zühlke, K. and Eichhorst, J. and Lehmann, M. and Knapp, S. and Weston, J. and von Kries, J.P. and Süssmuth, R.D. and Klussmann, E.
International Journal of Molecular Sciences 23 (2): 763. 11 January 2022

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D. and Hörtenhuber, M. and Balwierz, P.J. and Zehnder, T. and Mukarram, A.K. and Nepal, C. and Várnai, C. and Hadzhiev, Y. and Jimenez-Gonzalez, A. and Li, N. and Wragg, J. and D'Orazio, F.M. and Relic, D. and Pachkov, M. and Díaz, N. and Hernández-Rodríguez, B. and Chen, Z. and Stoiber, M. and Dong, M. and Stevens, I. and Ross, S.E. and Eagle, A. and Martin, R. and Obasaju, O. and Rastegar, S. and McGarvey, A.C. and Kopp, W. and Chambers, E. and Wang, D. and Kim, H.R. and Acemel, R.D. and Naranjo, S. and Łapiński, M. and Chong, V. and Mathavan, S. and Peers, B. and Sauka-Spengler, T. and Vingron, M. and Carninci, P. and Ohler, U. and Lacadie, S.A. and Burgess, S.M. and Winata, C. and van Eeden, F. and Vaquerizas, J.M. and Gómez-Skarmeta, J.L. and Onichtchouk, D. and Brown, B.J. and Bogdanovic, O. and van Nimwegen, E. and Westerfield, M. and Wardle, F.C and Daub, C.O. and Lenhard, B. and Müller, F.
Nature Genetics 54 (7): 1037-1050. July 2022

Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A. and Gündüz, I.B. and Franke, V. and Uyar, B. and Akalin, A.
Cancers 14 (22): 5604. 15 November 2022

Transcriptome analysis reveals high tumor heterogeneity with respect to re-activation of stemness and proliferation programs.
Baranovsky, A. and Ivanov, T. and Granovskaya, M. and Papatsenko, D. and Pervouchine, D.D.
PLoS ONE 17 (5): e0268626. 19 May 2022

PyZebraScope: an open-source platform for brain-wide neural activity imaging in zebrafish.
Barbara, R. and Nagathihalli Kantharaju, M. and Haruvi, R. and Harrington, K. and Kawashima, T.
Frontiers in Cell and Developmental Biology 10 : 875044. 19 May 2022

Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A. and Malhan, D. and Dumbani, M. and Dahlmann, M. and Stein, U. and Relógio, A.
Cancers 14 (14): 3458. 16 July 2022

Role of endothelial kinin B(1) receptor on the membrane potential of transgenic rat aorta.
Batista, C. and Sales, V.M. and Merino, V.F. and Bader, M. and Feres, T. and Pesquero, J.B.
Physiological Research 71 (4): 477-487. August 2022

Sexual dimorphism in extracellular matrix composition and viscoelasticity of the healthy and inflamed mouse brain.
Batzdorf, C.S. and Morr, A.S. and Bertalan, G. and Sack, I. and Silva, R.V. and Infante-Duarte, C.
Biology 11 (2): 230. 31 January 2022

State-of-the-art analytical methods of viral infections in human lung organoids.
Baumgardt, M. and Hülsemann, M. and Löwa, A. and Fatykhova, D. and Hoffmann, K. and Kessler, M. and Mieth, M. and Hellwig, K. and Frey, D. and Langenhagen, A. and Voss, A. and Obermayer, B. and Wyler, E. and Dökel, S. and Gruber, A.D. and Tölch, U. and Hippenstiel, S. and Hocke, A.C. and Hönzke, K.
PLoS ONE 17 (12): e0276115. 20 December 2022

Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics.
Bayram, S. and Razzaque, Y.S. and Geisberger, S. and Pietzke, M. and Fürst, S. and Vechiatto, C. and Forbes, M. and Mastrobuoni, G. and Kempa, S.
Frontiers in Molecular Biosciences 9 : 859787. 12 August 2022

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G. and Blume, A. and Demirel, F.G. and Bulut, S. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 73 (1): 5-17. June 2022

Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 72 (5): 175-184. May 2022

AQUA mutant protein quantification of endomyocardial biopsy-sized samples from a patient with hypertrophic cardiomyopathy.
Becker, E. and Francino, A. and Pich, A. and Perrot, A. and Kraft, T. and Radocaj, A.
Frontiers in Cardiovascular Medicine 9 : 816330. 21 February 2022

Claudin-targeted suicide gene therapy for claudin-overexpressing tumor cells by using modified clostridium perfringens enterotoxin (CPE).
Beier, L.S. and Piontek, J. and Piontek, A. and Protze, J. and Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521 (3): 173-188. 23 June 2022

Human primary muscle stem cells regenerate injured urethral sphincter in athymic rats.
Bekele, B.M. and Schöwel-Wolf, V. and Kieshauer, J. and Marg, A. and Busjahn, A. and Davis, S. and Nugent, G. and Ebert, A.K. and Spuler, S.
Animal Models and Experimental Medicine 5 (5): 453-460. October 2022

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
Belda, E. and Voland, L. and Tremaroli, V. and Falony, G. and Adriouch, S. and Assmann, K.E. and Prifiti, E. and Aron-Wisnewsky, J. and Debédat, J. and Le Roy, T. and Nielsen, T. and Amouyal, C. and André, S. and Andreelli, F. and Blüher, M. and Chakaroun, R. and Chilloux, J. and Coelho, L.P. and Dao, M.C. and Das, P. and Fellahi, S. and Forslund, S. and Galleron, N. and Hansen, T.H. and Holmes, B. and Ji, B. and Krogh Pedersen, H. and Le, P. and Le Chatelier, E. and Lewinter, C. and Mannerås-Holm, L. and Marquet, F. and Myridakis, A. and Pelloux, V. and Pons, N. and Quinquis, B. and Rouault, C. and Roume, H. and Salem, J.E. and Sokolovska, N. and Søndertoft, N.B. and Touch, S. and Vieira-Silva, S. and Galan, P. and Holst, J. and Gøtze, J.P. and Køber, L. and Vestergaard, H. and Hansen, T. and Hercberg, S. and Oppert, J.M. and Nielsen, J. and Letunic, I. and Dumas, M.E. and Stumvoll, M. and Pedersen, O.B. and Bork, P. and Ehrlich, S.D. and Zucker, J.D. and Bäckhed, F. and Raes, J. and Clément, K.
Gut 71 (12): 2463-2480. 7 November 2022

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.
Benaglio, P. and Zhu, H. and Okino, M.L. and Yan, J. and Elgamal, R. and Nariai, N. and Beebe, E. and Korgaonkar, K. and Qiu, Y. and Donovan, M.K.R. and Chiou, J. and Wang, G. and Newsome, J. and Kaur, J. and Miller, M. and Preissl, S. and Corban, S. and Aylward, A. and Taipale, J. and Ren, B. and Frazer, K.A. and Sander, M. and Gaulton, K.J.
Cell Genomics 2 (12): 100214. 14 December 2022

Association between B-cell depletion and attack risk in neuromyelitis optica spectrum disorder: An exploratory analysis from N-MOmentum, a double-blind, randomised, placebo-controlled, multicentre phase 2/3 trial.
Bennett, J.L. and Aktas, O. and Rees, W.A. and Smith, M.A. and Gunsior, M. and Yan, L. and She, D. and Cimbora, D. and Pittock, S.J. and Weinshenker, B.G. and Paul, F. and Marignier, R. and Wingerchuk, D. and Cutter, G. and Green, A. and Hartung, H.P. and Kim, H.J. and Fujihara, K. and Levy, M. and Katz, E. and Cree, B.A.C.
EBioMedicine 86 : 104321. December 2022

Electrocardiographic changes during initiation of lithium augmentation of antidepressant pharmacotherapy.
Berger, M. and Kermer, J. and Behr, J. and Schulz-Menger, J. and Bilal, S. and Osterland, S.L. and O'Malley, G. and Bschor, T. and Schlattmann, P. and Stamm, T. and Steinacher, B. and de Millas, W. and Richter, C. and Heinz, A. and Adli, M. and Buspavanich, P. and Ricken, R.
Journal of Clinical Psychopharmacology 42 (1): 87-91. January 2022

Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Berlak, M. and Tucker, E. and Dorel, M. and Winkler, A. and McGearey, A. and Rodriguez-Fos, E. and da Costa, B.M. and Barker, K. and Fyle, E. and Calton, E. and Eising, S. and Ober, K. and Hughes, D. and Koutroumanidou, E. and Carter, P. and Stankunaite, R. and Proszek, P. and Jain, N. and Rosswog, C. and Dorado-Garcia, H. and Molenaar, J.J. and Hubank, M. and Barone, G. and Anderson, J. and Lang, P. and Deubzer, H.E. and Künkele, A. and Fischer, M. and Eggert, A. and Kloft, C. and Henssen, A.G. and Boettcher, M. and Hertwig, F. and Blüthgen, N. and Chesler, L. and Schulte, J.H.
Molecular Cancer 21 (1): 126. 10 June 2022

Impact of the external school food environment on the associations of internal school food environment with high schoolers’ diet and BMI.
Betts, G.M. and Schwedhelm, C. and Lipsky, L.M. and Haynie, D.L. and Nansel, T.R.
Public Health Nutrition 25 (11): 3086-3095. November 2022

Elevated blood pressure in pregnant women with gestational diabetes according to the WHO criteria: importance of overweight.
Birukov, A. and Glintborg, D. and Schulze, M.B. and Jensen, T.K. and Kuxhaus, O. and Andersen, L.B. and Kräker, K. and Polemiti, E. and Jensen, B.L. and Jørgensen, J.S. and Dechend, R. and Andersen, M.S.
Journal of Hypertension 40 (8): 1614-1623. August 2022

The single-cell transcriptional landscape of lung carcinoid tumors.
Bischoff, P. and Trinks, A. and Wiederspahn, J. and Obermayer, B. and Pett, J.P. and Jurmeister, P. and Elsner, A. and Dziodzio, T. and Rückert, J.C. and Neudecker, J. and Falk, C. and Beule, D. and Sers, C. and Morkel, M. and Horst, D. and Klauschen, F. and Blüthgen, N.
International Journal of Cancer 150 (12): 2058-2071. 15 June 2022

Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R. and Dickinson, M. and Purtill, D. and Barba, P. and Santoro, A. and Hamad, N. and Kato, K. and Sureda, A. and Greil, R. and Thieblemont, C. and Morschhauser, F. and Janz, M. and Flinn, I. and Rabitsch, W. and Kwong, Y.L. and Kersten, M.J and Minnema, M.C. and Holte, H. and Chan, E.H.L. and Martinez-Lopez, J. and Müller, A.M.S. and Maziarz, R.T. and McGuirk, J.P. and Bachy, E. and Le Gouill, S. and Dreyling, M. and Harigae, H. and Bond, D. and Andreadis, C. and McSweeney, P. and Kharfan-Dabaja, M. and Newsome, S. and Degtyarev, E. and Awasthi, R. and Del Corral, C. and Andreola, G. and Masood, A. and Schuster, S.J. and Jäger, U. and Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386 (7): 629-639. 17 February 2022

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation.
Blassberg, R. and Patel, H. and Watson, T. and Gouti, M. and Metzis, V. and Delás, M.J. and Briscoe, J.
Nature Cell Biology 24 (5): 633-644. May 2022

Impact of dietary intervention on serum neurofilament light chain in multiple sclerosis.
Bock, M. and Steffen, F. and Zipp, F. and Bittner, S.
Neurology Neuroimmunology & Neuroinflammation 9 (1): e1102. January 2022

Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T. and Funck, K. and Wollweber, F. and Lisicki, E. and von der Malsburg, K. and von der Malsburg, A. and Laborenz, J. and Noel, J.K. and Hessenberger, M. and Jungbluth, S. and Bernert, C. and Kunz, S. and Riedel, D. and Lilie, H. and Jakobs, S. and van der Laan, M. and Daumke, O.
Science Advances 8 (35): eabo4946. 2 September 2022

SLM2 is a novel cardiac splicing factor involved in heart failure due to dilated cardiomyopathy.
Boeckel, J.N. and Möbius-Winkler, M. and Müller, M. and Rebs, S. and Eger, N. and Schoppe, L. and Tappu, R. and Kokot, K.E. and Kneuer, J.M. and Gaul, S. and Bordalo, D.M. and Lai, A. and Haas, J. and Ghanbari, M. and Drewe-Boss, P. and Liss, M. and Katus, H.A. and Ohler, U. and Gotthardt, M. and Laufs, U. and Streckfuss-Bömeke, K. and Meder, B.
Genomics Proteomics & Bioinformatics 20 (1): 129-146. February 2022

Lifelong effect of therapy in young patients with the cOL4A5 alport missense variant p.(Gly624Asp): a prospective cohort study.
Boeckhaus, J. and Hoefele, J. and Riedhammer, K.M. and Nagel, M. and Beck, B. and Choi, M. and Gollasch, M. and Bergmann, C. and Sonntag, J.E. and Troesch, V. and Stock, J. and Gross, O.
Nephrology Dialysis Transplantation 37 (12): 2496-2504. December 2022

Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska, R. and Mikecin, A.M. and Kaschutnig, P. and Fawaz, M. and Büchler-Schäff, M. and Le, D. and Ganuza, M. and Vollmer, A. and Paffenholz, S.V. and Asada, N. and Rodriguez-Correa, E. and Frauhammer, F. and Buettner, F. and Ball, M. and Knoch, J. and Stäble, S. and Walter, D. and Petri, A. and Carreño-Gonzalez, M.J. and Wagner, V. and Brors, B. and Haas, S. and Lipka, D.B. and Essers, M.A.G. and Weru, V. and Holland-Letz, T. and Mallm, J.P. and Rippe, K. and Krämer, S. and Schlesner, M. and McKinney Freeman, S. and Florian, M.C. and King, K.Y. and Frenette, P.S. and Rieger, M.A. and Milsom, M.D.
Cell Stem Cell 29 (8): 1273-1284. 4 August 2022

Full-length spatial transcriptomics reveals the unexplored isoform diversity of the myocardium post-MI.
Boileau, E. and Li, X. and Naarmann-de Vries, I.S. and Becker, C. and Casper, R. and Altmüller, J. and Leuschner, F. and Dieterich, C.
Frontiers in Genetics 13 : 912572. 22 July 2022

pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation.
Boix, O. and Martinez, M. and Vidal, S. and Giménez-Alejandre, M. and Palenzuela, L. and Lorenzo-Sanz, L. and Quevedo, L. and Moscoso, O. and Ruiz-Orera, J. and Ximénez-Embún, P. and Ciriaco, N. and Nuciforo, P. and Stephan-Otto Attolini, C. and Albà, M.M. and Muñoz, J. and Tian, T.V. and Varela, I. and Vivancos, A. and Ramón Y Cajal, S. and Muñoz, P. and Rivas, C. and Abad, M.
Nature Communications 13 (1): 6840. 11 November 2022

The impact of membrane protein diffusion on GPCR signaling.
Boltz, H.H. and Sirbu, A. and Stelzer, N. and de Lanerolle, P. and Winkelmann, S. and Annibale, P.
Cells 11 (10): 1660. 17 May 2022

Examination of the contributions of maternal/placental-derived galectin-1 to pregnancy outcome.
Borowski, S. and Freitag, N. and Urban, I. and Michel, G. and Barrientos, G. and Blois, S.M.
Methods in Molecular Biology 2442 : 603-619. 2022

Association of cholinesterase activities and POD in older adult abdominal surgical patients.
Bosancic, Z. and Spies, C.D. and Müller, A. and Winterer, G. and Piper, S.K. and Heinrich, M.
BMC Anesthesiology 22 (1): 293. 16 September 2022

Glucose-induced hemodynamic and metabolic response of skeletal muscle in heart failure patients with reduced vs. preserved ejection fraction-a pilot study.
Boschmann, M. and Klug, L. and Edelmann, F. and Sandek, A. and von Haehling, S. and Düngen, H.D. and Springer, J. and Anker, S.D. and Doehner, W. and Jauert, N.
Journal of Cardiovascular Development and Disease 9 (12): 456. 13 December 2022

Conditioning with fludarabine and treosulfan compared to FLAMSA-RIC in allogeneic stem cell transplantation for myeloid malignancies: a retrospective single-center analysis.
Braitsch, K. and Schwarz, A. and Koch, K. and Hubbuch, M. and Menzel, H. and Keller, U. and Götze, K.S. and Bassermann, F. and Herhaus, P. and Verbeek, M.
Annals of Hematology 101 (6): 1311-1319. June 2022

Central stress processing, T-cell responsivity to stress hormones, and disease severity in multiple sclerosis.
Brasanac, J. and Hetzer, S. and Asseyer, S. and Kuchling, J. and Bellmann-Strobl, J. and Ritter, K. and Gamradt, S. and Scheel, M. and Haynes, J.D. and Brandt, A.U. and Paul, F. and Gold, S.M. and Weygandt, M.
Brain Communications 4 (2): fcac086. 4 April 2022

Immune signature of multiple sclerosis-associated depression.
Brasanac, J. and Ramien, C. and Gamradt, S. and Tänzer, A. and Glau, L. and Ritter, K. and Patas, K. and Agorastos, A. and Wiedemann, K. and Demiralay, C. and Fischer, F. and Otte, C. and Bellmann-Strobl, J. and Friese, M.A. and Tolosa, E. and Paul, F. and Heesen, C. and Weygandt, M. and Gold, S.M.
Brain Behavior and Immunity 100 : 174-182. February 2022

Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways.
Braun, T. and Glass, M. and Wahnschaffe, L. and Otte, M. and Mayer, P. and Franitza, M. and Altmüller, J. and Hallek, M. and Hüttelmaier, S. and Schrader, A. and Herling, M.
Haematologica 107 (1): 187-200. January 2022

Noncanonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemia.
Braun, T. and Stachelscheid, J. and Bley, N. and Oberbeck, S. and Otte, M. and Müller, T.A. and Wahnschaffe, L. and Glaß, M. and Ommer, K. and Franitza, M. and Gathof, B. and Altmüller, J. and Hallek, M. and Auguin, D. and Hüttelmaier, S. and Schrader, A. and Herling, M.
Cancer Research 82 (9): 1818-1831. 1 May 2022

Relapse of NPM1-mutated AML with extramedullary manifestation 17 years after allogeneic hematopoietic stem cell transplantation.
Braune, J. and Rieger, K. and Blau, O. and Keller, U. and Bullinger, L. and Krönke, J.
Case Reports in Hematology 2022 : 3317936. 28 December 2022

TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck, F. and Fischer, B. and Witt, M. and Muschhammer, J. and Oelrich, J. and da Costa Avelar, P.H. and Tsoka, S. and Bullinger, L. and Seubert, E. and Smit, D.J. and Bokemeyer, C. and Ackermann, C. and Wellbrock, J. and Haag, F. and Fiedler, W.
Journal for ImmunoTherapy of Cancer 10 (12): e004794. 22 December 2022

Claudin-10a deficiency shifts proximal tubular Cl(-) permeability to cation selectivity via claudin-2 redistribution.
Breiderhoff, T. and Himmerkus, N. and Meoli, L. and Fromm, A. and Sewerin, S. and Kriuchkova, N. and Nagel, O. and Ladilov, Y. and Krug, S. and Quintanova, C. and Stumpp, M. and Garbe-Schönberg, D. and Westernströer, U. and Merkel, C. and Brinkhus, M. and Altmüller, J. and Schweiger, M. and Mueller, D. and Mutig, K. and Morawski, M. and Halbritter, J. and Milatz, S. and Bleich, M. and Günzel, D.
Journal of the American Society of Nephrology 33 (4): 699-717. April 2022

The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L. and Morao, A.K. and Kim, J. and Jimenez, D.S. and Maryn, N. and Bikkasani, K. and Carrozza, M.J. and Albritton, S.E. and Kramer, M. and Street, L.A. and Cerimi, K. and Schumann, V.F. and Bahry, E. and Preibisch, S. and Woehler, A. and Ercan, S.
Journal of Cell Science 135 (2): jcs258818. January 2022

Optimization of synthetic molecular reporters for a mesenchymal glioblastoma transcriptional program by integer programming.
Breitenbach, T. and Schmitt, M.J. and Dandekar, T.
Bioinformatics 38 (17): 4162-4171. 1 September 2022

Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs.
Broto, M. and Kaminski, M.M. and Adrianus, C. and Kim, N. and Greensmith, R. and Dissanayake-Perera, S. and Schubert, A.J. and Tan, X. and Kim, H. and Dighe, A.S. and Collins, J.J. and Stevens, M.M.
Nature Nanotechnology 17 (10): 1120-1126. October 2022

Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis.
Brune, S. and Høgestøl, E.A. and de Rodez Benavent, S.A. and Berg-Hansen, P. and Beyer, M.K. and Leikfoss, I.S. and Bos, S.D. and Sowa, P. and Brunborg, C. and Andorra, M. and Pulido Valdeolivas, I. and Asseyer, S. and Brandt, A. and Chien, C. and Scheel, M. and Blennow, K. and Zetterberg, H. and Kerlero de Rosbo, N. and Paul, F. and Uccelli, A. and Villoslada, P. and Berge, T. and Harbo, H.F.
Multiple Sclerosis Journal 28 (12): 1859-1870. October 2022

Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation.
Brunner, A.D. and Thielert, M. and Vasilopoulou, C. and Ammar, C. and Coscia, F. and Mund, A. and Hoerning, O.B. and Bache, N. and Apalategui, A. and Lubeck, M. and Richter, S. and Fischer, D.S. and Raether, O. and Park, M.A. and Meier, F. and Theis, F.J. and Mann, M.
Molecular Systems Biology 18 (3): e10798. 1 March 2022

Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Buchanan, C.J. and Gaunt, B. and Harrison, P.J. and Yang, Y. and Liu, J. and Khan, A. and Giltrap, A.M. and Le Bas, A. and Ward, P.N. and Gupta, K. and Dumoux, M. and Tan, T.K. and Schimaski, L. and Daga, S. and Picchiotti, N. and Baldassarri, M. and Benetti, E. and Fallerini, C. and Fava, F. and Giliberti, A. and Koukos, P.I. and Davy, M.J. and Lakshminarayanan, A. and Xue, X. and Papadakis, G. and Deimel, L.P. and Casablancas-Antràs, V. and Claridge, T.D.W. and Bonvin, A.M.J.J. and Sattentau, Q.J. and Furini, S. and Gori, M. and Huo, J. and Owens, R.J. and Schaffitzel, C. and Berger, I. and Renieri, A. and Naismith, J.H. and Baldwin, A.J. and Davis, B.G.
Science 377 (6604): eabm3125. 22 July 2022

The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.
Buffenstein, R. and Amoroso, V. and Andziak, B. and Avdieiev, S. and Azpurua, J. and Barker, A.J. and Bennett, N.C. and Brieño-Enríquez, M.A. and Bronner, G.N. and Coen, C. and Delaney, M.A. and Dengler-Crish, C.M. and Edrey, Y.H. and Faulkes, C.G. and Frankel, D. and Friedlander, G. and Gibney, P.A. and Gorbunova, V. and Hine, C. and Holmes, M.M. and Jarvis, J.U.M. and Kawamura, Y. and Kutsukake, N. and Kenyon, C. and Khaled, W.T. and Kikusui, T. and Kissil, J. and Lagestee, S. and Larson, J. and Lauer, A. and Lavrenchenko, L.A. and Lee, A. and Levitt, J.B. and Lewin, G.R. and Lewis Hardell, K.N. and Lin, T.D. and Mason, M.J. and McCloskey, D. and McMahon, M. and Miura, K. and Mogi, K. and Narayan, V. and O'Connor, T.P. and Okanoya, K. and O'Riain, M.J. and Park, T.J. and Place, N.J. and Podshivalova, K. and Pamenter, M.E. and Pyott, S.J. and Reznick, J. and Ruby, J.G. and Salmon, A.B. and Santos-Sacchi, J. and Sarko, D.K. and Seluanov, A. and Shepard, A. and Smith, M. and Storey, K.B. and Tian, X. and Vice, E.N. and Viltard, M. and Watarai, Ak. and Wywial, E. and Yamakawa, M. and Zemlemerova, E.D. and Zions, M. and Smith, E.S.J.
Biological Reviews 97 (1): 115-140. February 2022

The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression.
Bujanic, L. and Shevchuk, O. and von Kügelgen, N. and Kalinina, A. and Ludwik, K. and Koppstein, D. and Zerna, N. and Sickmann, A. and Chekulaeva, M.
RNA 28 (5): 766-779. May 2022

Generation of redirected engineered human chimeric antigen receptor (CAR) T cells.
Bunse, M. and Höpken, U.E.
Methods in Molecular Biology 2521 (3): 67-83. 23 June 2022

Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA interdisciplinary expert consensus.
Buske, C. and Dreyling, M. and Alvarez-Larrán, A. and Apperley, J. and Arcaini, L. and Besson, C. and Bullinger, L. and Corradini, P. and Della Porta, M.G. and Dimopoulos, M. and D’Sa, S. and Eich, H.T. and Foà, R. and Ghia, P. and Gomes da Silva, M. and Gribben, J. and Hajek, R. and Harrison, C. and Heuser, M. and Kiesewetter, B. and Kiladjian, J.J. and Kröger, N. and Moreau, P. and Passweg, J.R. and Peyvandi, F. and Rea, D. and Ribera, J.M. and Robak, T. and San-Miguel, J.F. and Santini, V. and Sanz, G. and Sonneveld, P. and von Lilienfeld-Toal, M. and Wendtner, C. and Pentheroudakis, G. and Passamonti, F.
ESMO Open 7 (2): 100403. April 2022

Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I. and Jaeschke, L. and Nimptsch, K. and Janke, J. and Herrmann, P. and Kobelt, D. and Kielstein, H. and Pischon, T. and Stein, U.
International Journal of Oncology 60 (2): 17. February 2022

Immune competence and spleen size scale with colony status in the naked mole-rat.
Bégay, V. and Cirovic, B. and Barker, A.J. and Klopffleisch, R. and Hart, D.W. and Bennett, N.C. and Lewin, G.R.
Open Biology 12 (4): 210292. 6 April 2022

WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephaly.
Bögershausen, N. and Krawczyk, H.E. and Jamra, R.A. and Lin, S.J. and Yigit, G. and Hüning, I. and Polo, A.M. and Vona, B. and Huang, K. and Schmidt, J. and Altmüller, J. and Luppe, J. and Platzer, K. and Dörgeloh, B.B. and Busche, A. and Biskup, S. and Mendes, M.I. and Smith, D.E.C. and Salomons, G.S. and Zibat, A. and Bültmann, E. and Nürnberg, P. and Spielmann, M. and Lemke, J.R. and Li, Y. and Zenker, M. and Varshney, G.K. and Hillen, H.S. and Kratz, C.P. and Wollnik, B.
Human Mutation 43 (10): 1454-1471. October 2022

Organoids as tools for fundamental discovery and translation - a Keystone Symposia report.
Cable, J. and Lutolf, M.P. and Fu, J. and Park, S.E. and Apostolou, A. and Chen, S. and Song, C.J. and Spence, J.R. and Liberali, P. and Lancaster, M. and Meier, A.B. and Pek, N.M.Q. and Wells, J.M. and Capeling, M.M. and Uzquiano, A. and Musah, S. and Huch, M. and Gouti, M. and Hombrink, P. and Quadrato, G. and Urenda, J.P.
Annals of the New York Academy of Sciences 1518 (1): 196-208. December 2022

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
Cabral-Marques, O. and Halpert, G. and Schimke, L.F. and Ostrinski, Y. and Vojdani, A. and Baiocchi, G.C. and Freire, P.P. and Filgueiras, I.S. and Zyskind, I. and Lattin, M.T. and Tran, F. and Schreiber, S. and Marques, A.H.C. and Plaça, D.R. and Fonseca, D.L.M. and Humrich, J.Y. and Müller, A. and Giil, L.M. and Graßhoff, H. and Schumann, A. and Hackel, A. and Junker, J. and Meyer, C. and Ochs, H.D. and Lavi, Y.B. and Scheibenbogen, C. and Dechend, R. and Jurisica, I. and Schulze-Forster, K. and Silverberg, J.I. and Amital, H. and Zimmerman, J. and Heidecke, H. and Rosenberg, A.Z. and Riemekasten, G. and Shoenfeld, Y.
Nature Communications 13 (1): 1220. 9 March 2022

AKAP18δ anchors and regulates CaMKII activity at phospholamban-SERCA2 and RYR.
Carlson, C.R. and Aronsen, J.M. and Bergan-Dahl, A. and Moutty, M.C. and Lunde, M. and Lunde, P.K. and Jarstadmarken, H. and Wanichawan, P. and Pereira, L. and Kolstad, T.R.S. and Dalhus, B. and Subramanian, H. and Hille, S. and Christensen, G. and Müller, O.J. and Nikolaev, V. and Bers, D.M. and Sjaastad, I. and Shen, X. and Louch, W.E. and Klussmann, E. and Sejersted, O.M.
Circulation Research 130 (1): 27-44. 7 January 2022

Seasonal variation in attacks of neuromyelitis optica spectrum disorders and multiple sclerosis: evaluation of 794 attacks from a nationwide registry in Argentina.
Carnero Contentti, E. and Lopez, P.A. and Pettinicchi, J.P. and Criniti, J. and Pappolla, A. and Miguez, J. and Patrucco, L. and Cristiano, E. and Liwacki, S. and Tkachuk, V. and Balbuena, M.E. and Vrech, C. and Deri, N. and Correale, J. and Marrodan, M. and Ysrraelit, M.C. and Leguizamon, F. and Luetic, G. and Menichini, M.L. and Tavolini, D. and Mainella, C. and Zanga, G. and Burgos, M. and Hryb, J. and Barboza, A. and Lazaro, L. and Alonso, R. and Fernández Liguori, N. and Nadur, D. and Chercoff, A. and Alonso Serena, M. and Caride, A. and Paul, F. and Rojas, J.I.
Multiple Sclerosis and Related Disorders 58 : 103466. February 2022

Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
Cefalu, W.T. and Andersen, D.K. and Arreaza-Rubín, G. and Pin, C.L. and Sato, S. and Verchere, C.B. and Woo, M. and Rosenblum, N.D.
Diabetes 71 (1): 1–22. January 2022

Building a Healthcare Alliance for Resourceful Medicine Offensive Against Neoplasms in hematologY added value framework for hematologic malignancies: a comparative analysis of existing tools.
Cerisoli, F. and Ali, F. and Bereczky, T. and Bolaños, N. and Bullinger, L. and Dhanasiri, S. and Gallagher, J. and Pérez, S.G. and Geissler, J. and Guillevic, Y. and Harrison, K. and Naoum, A. and Portulano, C. and Rodríguez Vicente, A.E. and Schulze-Rath, R. and Gómez, G.Y. and Sanz, G. and Hernández Rivas, J.M.
Value in Health 25 (10): 1760-1767. October 2022

Association of maintenance intravenous immunoglobulin with prevention of relapse in adult myelin oligodendrocyte glycoprotein antibody-associated disease.
Chen, J.J. and Huda, S. and Hacohen, Y. and Levy, M. and Lotan, I. and Wilf-Yarkoni, A. and Stiebel-Kalish, H. and Hellmann, M.A. and Sotirchos, E.S. and Henderson, A.D. and Pittock, S.J. and Bhatti, M.T. and Eggenberger, E.R. and Di Nome, M. and Kim, H.J. and Kim, S.H. and Saiz, A. and Paul, F. and Dale, R.C. and Ramanathan, S. and Palace, J. and Camera, V. and Leite, M.I. and Lam, B.L. and Bennett, J.L. and Mariotto, S. and Hodge, D. and Audoin, B. and Maillart, E. and Deschamps, R. and Pique, J. and Flanagan, E.P. and Marignier, R.
JAMA Neurology 79 (5): 518-525. 1 May 2022

OCT retinal nerve fiber layer thickness differentiates acute optic neuritis from MOG antibody-associated disease and Multiple Sclerosis: RNFL thickening in acute optic neuritis from MOGAD vs MS.
Chen, J.J. and Sotirchos, E.S. and Henderson, A.D. and Vasileiou, E.S. and Flanagan, E.P. and Bhatti, M.T. and Jamali, S. and Eggenberger, E.R. and Dinome, M. and Frohman, L.P. and Arnold, A.C. and Bonelli, L. and Seleme, N. and Mejia-Vergara, A.J. and Moss, H.E. and Padungkiatsagul, T. and Stiebel-Kalish, H. and Lotan, I. and Hellmann, M.A. and Hodge, D. and Oertel, F.C. and Paul, F. and Saidha, S. and Calabresi, P.A. and Pittock, S.J.
Multiple Sclerosis and Related Disorders 58 : 103525. February 2022

The intrinsic and extrinsic effects of TET proteins during gastrulation.
Cheng, S. and Mittnenzweig, M. and Mayshar, Y. and Lifshitz, A. and Dunjić, M. and Rais, Y. and Ben-Yair, R. and Gehrs, S. and Chomsky, E. and Mukamel, Z. and Rubinstein, H. and Schlereth, K. and Reines, N. and Orenbuch, A.H. and Tanay, A. and Stelzer, Y.
Cell 185 (17): 3169-3185. 18 August 2022

Prediction of high and low disease activity in early MS patients using multiple kernel learning identifies importance of lateral ventricle intensity.
Chien, C. and Seiler, M. and Eitel, F. and Schmitz-Hübsch, T. and Paul, F. and Ritter, K.
Multiple Sclerosis Journal Experimental Translational and Clinical 8 (3): 20552173221109770. 1 July 2022

Motor signature of autism spectrum disorder in adults without intellectual impairment.
Cho, A.B. and Otte, K. and Baskow, I. and Ehlen, F. and Maslahati, T. and Mansow-Model, S. and Schmitz-Hübsch, T. and Behnia, B. and Roepke, S.
Scientific Reports 12 (1): 7670. 10 May 2022

A high-resolution map of human RNA translation.
Chothani, S.P. and Adami, E. and Widjaja, A.A. and Langley, S.R. and Viswanathan, S. and Pua, C.J. and Zhihao, N.T. and Harmston, N. and D'Agostino, G. and Whiffin, N. and Mao, W. and Ouyang, J.F. and Lim, W.W. and Lim, S. and Lee, C.Q.E. and Grubman, A. and Chen, J. and Kovalik, J.P. and Tryggvason, K. and Polo, J.M. and Ho, L. and Cook, S.A. and Rackham, O.J.L. and Schafer, S.
Molecular Cell 82 (15): 2885-2899.e8. 4 August 2022

Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F. and Hablesreiter, R. and Hoyer, K. and Hennch, C. and Maluck-Böttcher, A. and Segler, A. and Madadi, A. and Frick, M. and Bullinger, L. and Briest, F. and Damm, F.
Leukemia 36 (4): 1102-1110. April 2022

Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki, F. and Bjordahl, R. and Goodridge, J.P. and Mahmood, S. and Gaidarova, S. and Abujarour, R. and Davis, Z.B. and Merino, A. and Tuininga, K. and Wang, H. and Kumar, A. and Groff, B. and Witty, A. and Bonello, G. and Huffman, J. and Dailey, T. and Lee, T.T. and Malmberg, K.J. and Walcheck, B. and Höpken, U. and Rehm, A. and Valamehr, B. and Miller, J.S.
Nature Communications 13 (1): 7341. 29 November 2022

A novel complex genomic rearrangement affecting the KCNJ2 regulatory region causes a variant of Cooks syndrome.
Cinque, L. and Micale, L. and Manara, E. and Esposito, A. and Palumbo, O. and Chiariello, A.M. and Bianco, S. and Guerri, G. and Bertelli, M. and Giuffrida, M.G. and Bernardini, L. and Notarangelo, A. and Nicodemi, M. and Castori, M.
Human Genetics 141 (2): 217-227. February 2022

Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E. and Althoff, S. and Ruß, J. and Rosnev, S. and Butze, M. and Pühl, M. and Frentsch, M. and Bullinger, L. and Na, I.K.
International Journal of Molecular Sciences 23 (6): 3207. 16 March 2022

Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6.
Cockman, M.E. and Sugimoto, Y. and Pegg, H.B. and Masson, N. and Salah, E. and Tumber, A. and Flynn, H.R. and Kirkpatrick, J.M. and Schofield, C.J. and Ratcliffe, P.J.
Proceedings of the National Academy of Sciences of the United States of America 119 (32): e2201483119. 9 August 2022

Towards the biogeography of prokaryotic genes.
Coelho, L.P. and Alves, R. and Del Río, Á.R. and Myers, P.N. and Cantalapiedra, C.P. and Giner-Lamia, J. and Schmidt, T.S. and Mende, D.R. and Orakov, A. and Letunic, I. and Hildebrand, F. and Van Rossum, T. and Forslund, S.K. and Khedkar, S. and Maistrenko, O.M. and Pan, S. and Jia, L. and Ferretti, P. and Sunagawa, S. and Zhao, X.M. and Nielsen, H.B. and Huerta-Cepas, J. and Bork, P.
Nature 601 (7892): 252-256. 13 January 2022

Efficient computational implementation of polymer physics models to explore chromatin structure.
Conte, M. and Esposito, A. and Fiorillo, L. and Campanile, R. and Annunziatella, C. and Corrado, A. and Chiariello, M.G. and Bianco, S. and Chiariello, A.M.
International Journal of Parallel, Emergent and Distributed Systems 37 (1): 91-102. January 2022

A polymer physics model to dissect genome organization in healthy and pathological phenotypes.
Conte, M. and Fiorillo, L. and Bianco, S. and Chiariello, A.M. and Esposito, A. and Musella, F. and Flora, F. and Abraham, A. and Nicodemi, M.
Methods in Molecular Biology 2301 : 307-316. 2022

Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding.
Conte, M. and Irani, E. and Chiariello, A.M. and Abraham, A. and Bianco, S. and Esposito, A. and Nicodemi, M.
Nature Communications 13 (1): 4070. 13 July 2022

Differences in age-related retinal and cortical atrophy rates in multiple sclerosis.
Cordano, C. and Nourbakhsh, B. and Yiu, H.H. and Papinutto, N. and Caverzasi, E. and Abdelhak, A. and Oertel, F.C. and Beaudry-Richard, A. and Santaniello, A. and Sacco, S. and Bennett, D.J. and Gomez, A. and Sigurdson, C.J. and Hauser, S.L. and Magliozzi, R. and Cree, B.A.C. and Henry, R.G. and Green, A.J.
Neurology 99 (15): e1685-e1693. 11 October 2022

Hypothalamic galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop.
Corradi, L. and Bruzzone, M. and Maschio, M.D. and Sawamiphak, S. and Filosa, A.
Current Biology 32 (7): 1497-1510. 11 April 2022

Using pERK immunostaining to quantify neuronal activity induced by stress in zebrafish larvae.
Corradi, L. and Zaupa, M. and Sawamiphak, S. and Filosa, A.
STAR Protocols 3 (4): 101731. 16 December 2022

Retinoids are not linked to risk of multiple sclerosis: a Danish nationwide cohort study.
Cortes-Figueiredo, F. and Nielsen, N.M. and Stenager, E. and Paul, F. and Hallas, J. and Kristensen, K.B.
European Journal of Neurology 2 (1): 247-256. 18 January 2022

Combining callers improves the detection of copy number variants from whole-genome sequencing.
Coutelier, M. and Holtgrewe, M. and Jäger, M. and Flöttman, R. and Mensah, M.A. and Spielmann, M. and Krawitz, P. and Horn, D. and Beule, D. and Mundlos, S.
European Journal of Human Genetics 30 (2): 178-186. February 2022

Svep1 stabilises developmental vascular anastomosis in reduced flow conditions.
Coxam, B. and Collins, R.T. and Hußmann, M. and Huisman, Y. and Meier, K. and Jung, S. and Bartels-Klein, E. and Szymborska, A. and Finotto, L. and Helker, C.S.M. and Stainier, D.Y.R. and Schulte-Merker, S. and Gerhardt, H.
Development 149 (6): dev199858. 24 March 2022

Myogenic vasoconstriction requires canonical G(q/11) signaling of the angiotensin II type 1 receptor.
Cui, Y. and Kassmann, M. and Nickel, S. and Zhang, C. and Alenina, N. and Anistan, Y.M. and Schleifenbaum, J. and Bader, M. and Welsh, D.G. and Huang, Y. and Gollasch, M.
Journal of the American Heart Association 11 (4): e022070. 15 February 2022

Associations of ultra-processed food intake with maternal weight change and cardiometabolic health and infant growth.
Cummings, J.R. and Lipsky, L.M. and Schwedhelm, C. and Liu, A. and Nansel, T.R.
International Journal of Behavioral Nutrition and Physical Activity 19 (1): 61. 26 May 2022

Hemostatic management in an infant with neuroblastoma and severe hemophilia B with extended half-life recombinant factor IX fusion protein.
Cuntz, F. and Deubzer, H.E. and Schulte, J.H. and Nimtz-Talaska, A. and Eggert, A. and Holzhauer, S.
Journal of Pediatric Hematology Oncology 44 (1): e246-e249. 1 January 2022

Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension.
Dahale, S. and Ruiz-Orera, J. and Silhavy, J. and Hübner, N. and van Heesch, S. and Pravenec, M. and Atanur, S.S.
Life Science Alliance 5 (4): e202101234. April 2022

Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M. and Monks, A. and Harris, E.D. and Kobelt, D. and Osterland, M. and Khaireddine, F. and Herrmann, P. and Kemmner, W. and Burock, S. and Walther, W. and Shoemaker, R.H. and Stein, U.
Cancers 14 (1): 37. 2022

Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases.
Damerau, A. and Kirchner, M. and Pfeiffenberger, M. and Ehlers, L. and Do Nguyen, D.H. and Mertins, P. and Bartek, B. and Maleitzke, T. and Palmowski, Y. and Hardt, S. and Winkler, T. and Buttgereit, F. and Gaber, T.
Metabolic Engineering 72 : 116-132. July 2022

Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19.
Dannebaum, R. and Suwalski, P. and Asgharian, H. and Du Zhipei, G. and Lin, H. and Weiner, J. and Holtgrewe, M. and Thibeault, C. and Müller, M. and Wang, X. and Karadeniz, Z. and Saccomanno, J. and Doehn, J.M. and Hübner, R.H. and Hinzmann, B. and Blüher, A. and Siemann, S. and Telman, D. and Suttorp, N. and Witzenrath, M. and Hippenstiel, S. and Skurk, C. and Poller, W. and Sander, L.E. and Beule, D. and Kurth, F. and Guettouche, T. and Landmesser, U. and Berka, J. and Luong, K. and Rubelt, F. and Heidecker, B.
EClinicalMedicine 48 : 101438. June 2022

Diagnostik, Therapie und die Bedeutung der Lebensqualität von Patienten mit chronischem Koronarsyndrom [Diagnostics, therapy and the importance of quality of life in patients with chronic coronary syndrome. Results oft the general practitioner care study ALTHEA].
Dechend, R.
MMW Fortschritte der Medizin 164 (Suppl 6): 11-17. 22 April 2022

Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
Degenhardt, F. and Ellinghaus, D. and Juzenas, S. and Lerga-Jaso, J. and Wendorff, M. and Maya-Miles, D. and Uellendahl-Werth, F. and ElAbd, H. and Rühlemann, M.C. and Arora, J. and Özer, O. and Lenning, O.B. and Myhre, R. and Vadla, M.S. and Wacker, E.M. and Wienbrandt, L. and Ortiz, A.B. and de Salazar, A. and Chercoles, A.G. and Palom, A. and Ruiz, A. and Garcia-Fernandez, A.E. and Blanco-Grau, A. and Mantovani, A. and Zanella, A. and Holten, A.R. and Mayer, A. and Bandera, A. and Cherubini, A. and Protti, A. and Aghemo, A. and Gerussi, A. and Ramirez, A. and Braun, A. and Nebel, A. and Barreira, A. and Lleo, A. and Teles, A. and Kildal, A.B. and Biondi, A. and Caballero-Garralda, A. and Ganna, A. and Gori, A. and Glück, A. and Lind, A. and Tanck, A. and Hinney, A. and Nolla, A.C. and Fracanzani, A.L. and Peschuck, A. and Cavallero, A. and Dyrhol-Riise, A.M. and Ruello, A. and Julià, A. and Muscatello, A. and Pesenti, A. and Voza, A. and Rando-Segura, A. and Solier, A. and Schmidt, 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Rodriguez-Frias, F. and Hanses, F. and Müller, F. and Hemmrich-Stanisak, G. and Bellani, G. and Grasselli, G. and Pezzoli, G. and Costantino, G. and Albano, G. and Cardamone, G. and Bellelli, G. and Citerio, G. and Foti, G. and Lamorte, G. and Matullo, G. and Baselli, G. and Kurihara, H. and Neb, H. and My, I. and Kurth, I. and Hernández, I. and Pink, I. and Rojas, I. and Galván-Femenia, I. and Holter, J.C. and Afset, J.E. and Heyckendorf, J. and Kässens, J. and Damås, J.K. and Rybniker, J. and Altmüller, J. and Ampuero, J. and Martín, J. and Erdmann, J. and Banales, J.M. and Badia, J.R. and Dopazo, J. and Schneider, J. and Bergan, J. and Barretina, J. and Walter, J. and Quero, J.H. and Goikoetxea, J. and Delgado, J. and Guerrero, J.M. and Fazaal, J. and Kraft, J. and Schröder, J. and Risnes, K. and Banasik, K. and Müller, K.E. and Gaede, K.I. and Garcia-Etxebarria, K. and Tonby, K. and Heggelund, L. and Izquierdo-Sanchez, L. and Bettini, L.Rachele and Sumoy, L. and Sander, L.E. and Lippert, L.J. and Terranova, L. and Nkambule, L. and Knopp, L. and Gustad, L.T. and Garbarino, L. and Santoro, L. and Téllez, L. and Roade, L. and Ostadreza, M. and Intxausti, M. and Kogevinas, M. and Riveiro-Barciela, M. and Berger, M.M. and Schaefer, M. and Niemi, M.E.K. and Gutiérrez-Stampa, M.A. and Carrabba, M. and Figuera Basso, M.E. and Valsecchi, M.G. and Hernandez-Tejero, M. and Vehreschild, M.J.G.T and Manunta, M. and Acosta-Herrera, M. and D'Angiò, M. and Baldini, M. and Cazzaniga, M. and Grimsrud, M.M. and Cornberg, M. and Nöthen, M.M. and Marquié, M. and Castoldi, M. and Cordioli, M. and Cecconi, M. and D'Amato, M. and Augustin, M. and Tomasi, M. and Boada, M. and Dreher, M. and Seilmaier, M.J. and Joannidis, M. and Wittig, M. and Mazzocco, M. and Ciccarelli, M. and Rodríguez-Gandía, M. and Bocciolone, M. and Miozzo, M. and Ayo, N.I. and Blay, N. and Chueca, N. and Montano, N. and Braun, N. and Ludwig, N. and Marx, N. and Martínez, N. and Cornely, O.A. and Witzke, O. and Palmieri, O. and Faverio, P. and Preatoni, P. and Bonfanti, P. and Omodei, P. and Tentorio, P. and Castro, P. and Rodrigues, P.M. and España, P.P. and Hoffmann, P. and Rosenstiel, P. and Schommers, P. and Suwalski, P. and Pablo, R. and Ferrer, R. and Bals, R. and Gualtierotti, R. and Gallego-Durán, R. and Nieto, R. and Carpani, R. and Morilla, R. and Badalamenti, S. and Haider, S. and Ciesek, S. and May, S. and Bombace, S. and Marsal, S. and Pigazzini, S. and Klein, S. and Pelusi, S. and Wilfling, S. and Bosari, S. and Volland, S. and Brunak, S. and Raychaudhuri, S. and Schreiber, S. and Heilmann-Heimbach, S. and Aliberti, S. and Ripke, S. and Dudman, S. and Wesse, T. and Zheng, T. and Bahmer, T. and Eggermann, T. and Illig, T. and Brenner, T. and Pumarola, T. and Feldt, T. and Folseraas, T. and Cejudo, T.G. and Landmesser, U. and Protzer, U. and Hehr, U. and Rimoldi, V. and Monzani, V. and Skogen, V. and Keitel, V. and Kopfnagel, V. and Friaza, V. and Andrade, V. and Moreno, V. and Albrecht, W. and Peter, W. and Poller, W. and Farre, X. and Yi, X. and Wang, X. and Khodamoradi, Y. and Karadeniz, Z. and Latiano, A. and Goerg, S. and Bacher, P. and Koehler, P. and Tran, F. and Zoller, H. and Schulte, E.C. and Heidecker, B. and Ludwig, K.U. and Fernández, J. and Romero-Gómez, M. and Albillos, A. and Invernizzi, P. and Buti, M. and Duga, S. and Bujanda, L. and Hov, J.R. and Lenz, T.L. and Asselta, R. and Cid, R. and Valenti, L. and Karlsen, T.H. and Cáceres, M. and Franke, A.
Human Molecular Genetics 31 (23): 3945-3966. 1 December 2022

Intranasal SARS-CoV-2 spike-based immunisation adjuvanted with polyethyleneimine elicits mucosal and systemic humoral responses in mice.
Deimel, L.P. and Liu, X. and Gilbert-Jaramillo, J. and Liu, S. and James, W.S. and Sattentau, Q.J.
Journal of Immunological Methods 511 : 113380. December 2022

High thermostability improves neutralizing antibody responses induced by native-like HIV-1 envelope trimers.
Del Moral-Sánchez, I. and Russell, R.A. and Schermer, E.E. and Cottrell, C.A. and Allen, J.D. and Torrents de la Peña, A. and LaBranche, C.. and Kumar, S. and Crispin, M. and Ward, A.B. and Montefiori, D.C. and Sattentau, Q.J. and Sliepen, K. and Sanders, R.W.
NPJ Vaccines 7 (1): 27. 28 February 2022

Prevalence of hypertension and possible risk factors of hypertension unawareness among individuals aged 30-75 years from two Panamanian provinces: results from population-based cross-sectional studies, 2010 and 2019.
Del Rio, A.I. and Moreno Velásquez, I. and Roa, R. and Montenegro Mendoza, R. and Motta, J. and Quintana, H.K.
PLoS ONE 17 (11): e0276222. 28 November 2022

B(1) inhomogeneity correction of RARE MRI at low SNR: quantitative in vivo (19)F MRI of mouse neuroinflammation with a cryogenically-cooled transceive surface radiofrequency probe.
Delgado, P.R. and Kuehne, A. and Aravina, M. and Millward, J.M. and Vazquez, A. and Starke, L. and Waiczies, H. and Pohlmann, A. and Niendorf, T. and Waiczies, S.
Magnetic Resonance in Medicine 87 (4): 1952-1970. April 2022

Functional repertoire convergence of distantly related eukaryotic plankton lineages abundant in the sunlit ocean.
Delmont, T.O. and Gaia, M. and Hinsinger, D.D. and Frémont, P. and Vanni, C. and Fernandez-Guerra, A. and Eren, A.M. and Kourlaiev, A. and d'Agata, L. and Clayssen, Q. and Villar, E. and Labadie, K. and Cruaud, C. and Poulain, J. and Da Silva, C. and Wessner, M. and Noel, B. and Aury, J.M. and de Vargas, C. and Bowler, C. and Karsenti, E. and Pelletier, E. and Wincker, P. and Jaillon, O.
Cell Genomics 2 (5): 100123. 11 May 2022

Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Demel, U.M. and Böger, M. and Yousefian, S. and Grunert, C. and Zhang, L. and Hotz, P.W. and Gottschlich, A. and Köse, H. and Isaakidis, K. and Vonficht, D. and Grünschläger, F. and Rohleder, E. and Wagner, K. and Dönig, J. and Igl, V. and Brzezicha, B. and Baumgartner, F. and Habringer, S. and Löber, J. and Chapuy, B. and Weidinger, C. and Kobold, S. and Haas, S. and Busse, A.B. and Müller, S. and Wirth, M. and Schick, M. and Keller, U.
Journal of Clinical Investigation 132 (9): e152383. 2 May 2022

A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo.
Demel, U.M. and Lutz, R. and Sujer, S. and Demerdash, Y. and Sood, S. and Grünschläger, F. and Kuck, A. and Werner, P. and Blaszkiewicz, S. and Uckelmann, H.J. and Haas, S. and Essers, M.
Blood Advances 6 (11): 3513-3528. 10 June 2022

Traveling volunteers: a multi-vendor, multi-center study on reproducibility and comparability of 4D flow derived aortic hemodynamics in cardiovascular magnetic resonance.
Demir, A. and Wiesemann, S. and Erley, J. and Schmitter, S. and Trauzeddel, R.F. and Pieske, B. and Hansmann, J. and Kelle, S. and Schulz-Menger, J.
Journal of Magnetic Resonance Imaging 55 (1): 211-222. January 2022

Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S. and Bittner, A. and Frick, M. and Kase, J. and Hoffmann, J. and Trenker, C. and Keller, U. and Bogner, C. and Hüttmann, A. and Dürig, J. and Janz, M. and Mathas, S. and Marks, R. and Krohn, U. and Na, I.K. and Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 63 (1): 84-92. January 2022

A comparison of solvent-based extraction methods to assess the central carbon metabolites in mouse bone and muscle.
Dias, D.B. and Fritsche-Guenther, R. and Gutmann, F. and Duda, G.N. and Kirwan, J. and Poh, P.S.P.
Metabolites 12 (5): 453. 18 May 2022

Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
Dieckmann, S. and Strohmeyer, A. and Willershäuser, M. and Maurer, S.F. and Wurst, W. and Marschall, S. and Hrabě de Angelis, M. and Kühn, R. and Worthmann, A. and Fuh, M.M. and Heeren, J. and Köhler, N. and Pauling, J.K. and Klingenspor, M.
American Journal of Physiology Endocrinology and Metabolism 322 (2): E85-E100. February 2022

Motion-compensated fat-water imaging for 3D cardiac MRI at ultra-high fields.
Dietrich, S. and Aigner, C.S. and Mayer, J. and Kolbitsch, C. and Schulz-Menger, J. and Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 87 (6): 2621-2636. June 2022

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice.
Dietrich, S. and Company, C. and Song, K. and Lowenstein, E.D. and Riedel, L. and Birchmeier, C. and Gargiulo, G. and Zampieri, N.
Nature Communications 13 (1): 6867. 11 November 2022

Hmga2 protein loss alters nuclear envelope and 3D chromatin structure.
Divisato, G. and Chiariello, A.M. and Esposito, A. and Zoppoli, P. and Zambelli, F. and Elia, M.A. and Pesole, G. and Incarnato, D. and Passaro, F. and Piscitelli, S. and Oliviero, S. and Nicodemi, M. and Parisi, S. and Russo, T.
BMC Biology 20 (1): 171. 2 August 2022

Brief research report: Quantitative analysis of potential coronary microvascular disease in suspected long-COVID syndrome.
Doeblin, P. and Steinbeis, F. and Scannell, C.M. and Goetze, C. and Al-Tabatabaee, S. and Erley, J. and Faragli, A. and Pröpper, F. and Witzenrath, M. and Zoller, T. and Stehning, C. and Gerhardt, H. and Sánchez-González, J. and Alskaf, E. and Kühne, T. and Pieske, B. and Tschöpe, C. and Chiribiri, A. and Kelle, S.
Frontiers in Cardiovascular Medicine 9 : 877416. 31 May 2022

NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer.
Doffo, J. and Bamopoulos, S.A. and Köse, H. and Orben, F. and Zang, C. and Pons, M. and den Dekker, A.T. and Brouwer, R.W.W. and Baluapuri, A. and Habringer, S. and Reichert, M. and Illendula, A. and Krämer, O.H. and Schick, M. and Wolf, E. and van IJcken, W.F.J. and Esposito, I. and Keller, U. and Schneider, G. and Wirth, M.
Proceedings of the National Academy of Sciences of the United States of America 119 (9): e2105691119. 1 March 2022

Identifying tumor cells at the single-cell level using machine learning.
Dohmen, J. and Baranovskii, A. and Ronen, J. and Uyar, B. and Franke, V. and Akalin, A.
Genome Biology 23 (1): 123. 30 May 2022

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H. and Pusch, F. and Bei, Y. and von Stebut, J. and Ibáñez, G. and Guillan, K. and Imami, K. and Gürgen, D. and Rolff, J. and Helmsauer, K. and Meyer-Liesener, S. and Timme, N. and Bardinet, V. and Chamorro González, R. and MacArthur, I.C. and Chen, C.Y. and Schulz, J. and Wengner, A.M. and Furth, C. and Lala, B. and Eggert, A. and Seifert, G. and Hundsoerfer, P. and Kirchner, M. and Mertins, P. and Selbach, M. and Lissat, A. and Dubois, F. and Horst, D. and Schulte, J.H. and Spuler, S. and You, D. and Dela Cruz, F. and Kung, A.L. and Haase, K. and Di Virgilio, M. and Scheer, M. and Ortiz, M.V. and Henssen, A.G.
Nature Communications 13 (1): 4297. 25 July 2022

Simultaneous imaging and flow-cytometry-based detection of multiple fluorescent senescence markers in therapy-induced senescent cancer cells.
Dovjak, E. and Mairhofer, M. and Wöß, C. and Qi, J. and Fan, D.N.Y. and Schmitt, C.A. and Yu, Y.
Journal of Visualized Experiments (185): e63973. 12 July 2022

Increase in mental disorders during the COVID-19 pandemic -- the role of occupational and financial strains. An analysis of the German National Cohort (NAKO) Study.
Dragano, N. and Reuter, M. and Peters, A. and Engels, M. and Schmidt, B. and Greiser, K.H. and Bohn, B. and Riedel-Heller, S. and Karch, A. and Mikolajczyk, R. and Krause, G. and Lang, O. and Panreck, L. and Rietschel, M. and Brenner, H. and Fischer, B. and Franzke, C.W. and Gastell, S. and Holleczek, B. and Jöckel, K.H. and Kaaks, R. and Keil, T. and Kluttig, A. and Kuß, O. and Legath, N. and Leitzmann, M. and Lieb, W. and Meinke-Franze, C. and Michels, K.B. and Obi, N. and Pischon, T. and Feinkohl, I. and Rospleszcz, S. and Schikowski, T. and Schulze, M.B. and Stang, A. and Völzke, H. and Willich, S.N. and Wirkner, K. and Zeeb, H. and Ahrens, W. and Berger, K.
Deutsches Arzteblatt International 119 (11): 179-187. 18 March 2022

Deep learning for prediction of population health costs.
Drewe-Boss, P. and Enders, D. and Walker, J. and Ohler, U.
BMC Medical Informatics and Decision Making 22 (1): 32. 3 February 2022

Uncovering the contribution of moderate-penetrance susceptibility genes to breast cancer by whole-exome sequencing and targeted enrichment sequencing of candidate genes in women of European ancestry.
Dumont, M. and Weber-Lassalle, N. and Joly-Beauparlant, C. and Ernst, C. and Droit, A. and Feng, B.J. and Dubois, S. and Collin-Deschesnes, A.C. and Soucy, P. and Vallée, M. and Fournier, F. and Lemaçon, A. and Adank, M.A. and Allen, J. and Altmüller, J. and Arnold, N. and Ausems, M.G.E.M. and Berutti, R. and Bolla, M.K. and Bull, S. and Carvalho, S. and Cornelissen, S. and Dufault, M.R. and Dunning, A.M. and Engel, C. and Gehrig, A. and Geurts-Giele, W.R.R. and Gieger, C. and Green, J. and Hackmann, K. and Helmy, M. and Hentschel, J. and Hogervorst, F.B.L. and Hollestelle, A. and Hooning, M.J. and Horváth, J. and Ikram, M.A. and Kaulfuß, S. and Keeman, R. and Kuang, D. and Luccarini, C. and Maier, W. and Martens, J.W.M. and Niederacher, D. and Nürnberg, P. and Ott, C.E. and Peters, A. and Pharoah, P.D.P. and Ramirez, A. and Ramser, J. and Riedel-Heller, S. and Schmidt, G. and Shah, M. and Scherer, M. and Stäbler, A. and Strom, T.M. and Sutter, C. and Thiele, H. and van Asperen, C.J. and van der Kolk, L. and van der Luijt, R.B. and Volk, A.E. and Wagner, M. and Waisfisz, Q. and Wang, Q. and Wang-Gohrke, S. and Weber, B.H.F. and Devilee, P. and Tavtigian, S. and Bader, G.D. and Meindl, A. and Goldgar, D.E. and Andrulis, I.L. and Schmutzler, R.K. and Easton, D.F. and Schmidt, M.K. and Hahnen, E. and Simard, J.
Cancers 14 (14): 3363. 11 July 2022

Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth.
Dzamukova, M. and Brunner, T.M. and Miotla-Zarebska, J. and Heinrich, F. and Brylka, L. and Mashreghi, M.F. and Kusumbe, A. and Kühn, R. and Schinke, T. and Vincent, T.L.. and Löhning, M.
Nature Communications 13 (1): 3059. 1 June 2022

Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications.
Döhner, H. and Weber, D. and Krzykalla, J. and Fiedler, W. and Wulf, G.G. and Salih, H.R. and Lübbert, M. and Kühn, M. and Schroeder, T. and Salwender, H. and Götze, K.S. and Westermann, J. and Fransecky, L. and Mayer, K. and Hertenstein, B. and Ringhoffer, M. and Tischler, H.J. and Machherndl-Spandl, S. and Schrade, A. and Paschka, P. and Gaidzik, V.I. and Theis, F. and Thol, F.R. and Heuser, M. and Schlenk, R.F. and Bullinger, L. and Saadati, M. and Benner, A. and Larson, R.A. and Stone, R.M. and Döhner, K. and Ganser, A.
Blood Advances 6 (18): 5345-5355. 27 September 2022

C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages.
Dörr, D. and Obermayer, B. and Weiner, J.M. and Zimmermann, K. and Anania, C. and Wagner, L.K. and Lyras, E.M. and Sapozhnikova, V. and Lara-Astiaso, D. and Prósper, F. and Lang, R. and Lupiáñez, D.G. and Beule, D. and Höpken, U.E. and Leutz, A. and Mildner, A.
Science Immunology 7 (75): eabj0140. September 2022

Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T(H)2-biased immunization.
Ebenig, A. and Muraleedharan, S. and Kazmierski, J. and Todt, D. and Auste, A. and Anzaghe, M. and Gömer, A. and Postmus, D. and Gogesch, P. and Niles, M. and Plesker, R. and Miskey, C. and Gellhorn Serra, M. and Breithaupt, A. and Hörner, C. and Kruip, C. and Ehmann, R. and Ivics, Z. and Waibler, Z. and Pfaender, S. and Wyler, E. and Landthaler, M. and Kupke, A. and Nouailles, G. and Goffinet, C. and Brown, R.J.P and Mühlebach, M.D.
Cell Reports 40 (7): 111214. 16 August 2022

Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
Ebert, M.J. and Jerke, U. and Eulenberg-Gustavus, C. and Kling, L. and Jenne, D.E. and Kirchner, M. and Mertins, P. and Bieringer, M. and Elitok, S. and Eckardt, K.U. and Schreiber, A. and Salama, A.D. and Kettritz, R.
Journal of Clinical Investigation 132 (23): e160089. 1 December 2022

TCR and CAR engineering of primary human T cells.
Edes, I. and Clauss, J. and Stahn, R. and Sada Japp, A. and Lorenz, F.K.M.
Methods in Molecular Biology 2521 (3): 85-93. 23 June 2022

Gender differences in perceptions and attitudes of medical students towards neurosurgery: a german nationwide survey.
Efe, I.E. and Aliyeva, I. and Beyaztas, D. and Swiatek, V.M. and Esene, I.N. and Abdulrauf, S.I.
World Neurosurgery 163 : 96-103. July 2022

The anti-glucocorticoid receptor antibody clone 5E4: raising awareness of unspecific antibody binding.
Ehlers, L. and Kirchner, M. and Mertins, P. and Strehl, C. and Buttgereit, F. and Gaber, T.
International Journal of Molecular Sciences 23 (9): 5049. 2 May 2022

Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL - long-term follow-up from the prospective ALL-SCT 2003 trial.
Eichinger, A. and Poetschger, U. and Glogova, E. and Bader, P. and Basu, O. and Beier, R. and Burkhardt, B. and Classen, C.F. and Claviez, A. and Corbacioglu, S. and Deubzer, H.E. and Greil, J. and Gruhn, B. and Güngör, T. and Kafa, K. and Kühl, J.S. and Lang, P. and Lange, B.S. and Meisel, R. and Müller, I. and Sauer, M.G. and Schlegel, P.G. and Schulz, A. and Stachel, D. and Strahm, B. and Wawer, A. and Peters, C. and Albert, M.H.
Leukemia 36 (11): 2567-2576. November 2022

Die Rolle der Hyper- und Hypohydrogenämie im klinischen Alltag - Warum pH? [The role of hyperhydrogenemia and hypohydrogenemia in the clinical setting - Why pH?].
Elitok, S. and Luft, F.C.
Nephrologie 17 : 339-353. September 2022

An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils.
Ellson, C.D. and Goretti Riça, I. and Kim, J.S. and Huang, Y.M.M. and Lim, D. and Mitra, T. and Hsu, A. and Wei, E.X. and Barrett, C.D. and Otterbein, L.E. and Hauser, C.J. and Wahl, M. and Delbrück, H. and Heinemann, U. and Oschkinat, H. and Chang, C.E.A. and Yaffe, M.B.
Journal of Molecular Biology 434 (9): 167533. 15 May 2022

The spontaneous course of human herpesvirus 6 DNA-associated myocarditis and the effect of immunosuppressive intervention.
Elsanhoury, A. and Kühl, U. and Stautner, B. and Klein, O. and Krannich, A. and Morris, D. and Willner, M. and Jankowska, E. and Klingel, K. and Van Linthout, S. and Tschöpe, C.
Viruses 14 (2): 299. February 2022

Walking parameters of older adults from a lower back inertial measurement unit, a 6-year longitudinal observational study.
Elshehabi, M. and Del Din, S. and Hobert, M.A. and Warmerdam, E. and Sünkel, U. and Schmitz-Hübsch, T. and Behncke, L.M. and Heinzel, S. and Brockmann, K. and Metzger, F.G. and Schlenstedt, C. and Rochester, L. and Hansen, C. and Berg, D. and Maetzler, W.
Frontiers in Aging Neuroscience 14 : 789220. 8 September 2022

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M. and Mücke, M.B. and Pallien, T. and Markó, L. and Sholokh, A. and Schächterle, C. and Aydin, A. and Kidd, A. and Walter, S. and Esmati, Y. and McMurray, B.J. and Lato, D.F. and Sunaga-Franze, D.Y. and Dierks, P.H. and Flores, B.I.M. and Walker-Gray, R. and Gong, M. and Merticariu, C. and Zühlke, K. and Russwurm, M. and Liu, T. and Batolomaeus, T.U.P. and Pautz, S. and Schelenz, S. and Taube, M. and Napieczynska, H. and Heuser, A. and Eichhorst, J. and Lehmann, M. and Miller, D.C. and Diecke, S. and Qadri, F. and Popova, E. and Langanki, R. and Movsesian, M.A. and Herberg, F.W. and Forslund, S.K. and Müller, D.N. and Borodina, T. and Maass, P.G. and Bähring, S. and Hübner, N. and Bader, M. and Klussmann, E.
Circulation 146 (23): 1758-1778. 6 December 2022

Stammzelltherapien für Muskeldystrophien.
Escobar, H.
BIOspektrum 28 : 493–496. September 2022

Evaluating metallic artefact of biodegradable magnesium-based implants in magnetic resonance imaging.
Espiritu, J. and Berangi, M. and Yiannakou, C. and Silva, E. and Francischello, R. and Kuehne, A. and Niendorf, T. and Könneker, S. and Willumeit-Römer, R. and Seitz, J.M.
Bioactive Materials 15 : 382-391. September 2022

Polymer physics reveals a combinatorial code linking 3D chromatin architecture to 1D chromatin states.
Esposito, A. and Bianco, S. and Chiariello, A.M. and Abraham, A. and Fiorillo, L. and Conte, M. and Campanile, R. and Nicodemi, M.
Cell Reports 38 (13): 110601. 29 March 2022

Evidence for recombinant GRP78, CALR, PDIA3 and GPI as mediators of genetic instability in human CD34+ cells.
Fabarius, A. and Samra, V. and Drews, O. and Mörz, H. and Bierbaum, M. and Darwich, A. and Weiss, C. and Brendel, S. and Kleiner, H. and Seifarth, W. and Greffrath, W. and Hofmann, W.K. and Schmitt, C.A. and Popp, H.D.
Cancers 14 (12): 2883. 11 June 2022

Development of a machine learning approach for local-scale ozone forecasting: application to Kennewick, WA.
Fan, K. and Dhammapala, R. and Harrington, K. and Lamastro, R. and Lamb, B. and Lee, Y.
Frontiers in Big Data 5 : 781309. 10 February 2022

Post-operative cognitive impairment: a cognitive epidemiology perspective.
Feinkohl, I.
Journal of Intelligence 10 (1): 18. 11 March 2022

A similarity scaling approach for organ-on-chip devices.
Feng, J.J. and Hedtrich, S.
Lab on a Chip 22 (19): 3663-3667. 7 October 2022

Isotropic 3D compressed sensing (CS) based sequence is comparable to 2D-LGE in left ventricular scar quantification in different disease entities.
Fenski, M. and Grandy, T.H. and Viezzer, D. and Kertusha, S. and Schmidt, M. and Forman, C. and Schulz-Menger, J.
International Journal of Cardiovascular Imaging 38 (8): 1837-1850. August 2022

Assessing evolutionary and developmental transcriptome dynamics in homologous cell types.
Feregrino, C. and Tschopp, P.
Developmental Dynamics 251 (9): 1472-1489. September 2022

Calcium-permeable channelrhodopsins for the photocontrol of calcium signalling.
Fernandez Lahore, R.G. and Pampaloni, N.P. and Schiewer, E. and Heim, M.M. and Tillert, L. and Vierock, J. and Oppermann, J. and Walther, J. and Schmitz, D. and Owald, D. and Plested, A.J.R. and Rost, B.R. and Hegemann, P.
Nature Communications 13 (1): 7844. 21 December 2022

Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer's disease.
Fernández Zapata, C. and Giacomello, G. and Spruth, E.J. and Middeldorp, J. and Gallaccio, G. and Dehlinger, A. and Dames, C. and Leman, J.K.H. and van Dijk, R.E. and Meisel, A. and Schlickeiser, S. and Kunkel, D. and Hol, E.M. and Paul, F. and Parr, M.K. and Priller, J. and Böttcher, C.
Nature Communications 13 (1): 7210. 23 November 2022

Recent analytical approaches for the study of bioavailability and metabolism of bioactive phenolic compounds.
Fernández-Ochoa, Á. and Cádiz-Gurrea, M.L. and Fernández-Moreno, P. and Rojas-García, A. and Arráez-Román, D. and Segura-Carretero, A.
Molecules 27 (3): 777. 25 January 2022

Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics.
Ferrante, F. and Giaimo, B.D. and Friedrich, T. and Sugino, T. and Mertens, D. and Kugler, S. and Gahr, B.M. and Just, S. and Pan, L. and Bartkuhn, M. and Potente, M. and Oswald, F. and Borggrefe, T.
Cell Death & Disease 13 (7): 600. 12 July 2022

Long-term efficacy, safety and neurotolerability of MATRix regimen followed by autologous transplant in primary CNS lymphoma: 7-year results of the IELSG32 randomized trial.
Ferreri, A.J.M. and Cwynarski, K. and Pulczynski, E. and Fox, C.P. and Schorb, E. and Celico, C. and Falautano, M. and Nonis, A. and La Rosée, P. and Binder, M. and Fabbri, A. and Ilariucci, F. and Krampera, M. and Roth, Al. and Hemmaway, C. and Johnson, P.W. and Linton, K.M. and Pukrop, T. and Gørløv, J.S. and Balzarotti, M. and Hess, G. and Keller, U. and Stilgenbauer, S. and Panse, J. and Tucci, A. and Orsucci, L. and Pisani, F. and Zanni, M. and Krause, S.W. and Schmoll, H.J. and Hertenstein, B. and Rummel, M. and Smith, J. and Thurner, L. and Cabras, G. and Pennese, E. and Ponzoni, M. and Deckert, M. and Politi, L.S. and Finke, J. and Ferranti, A. and Cozens, K. and Burger, E. and Ielmini, N. and Cavalli, F. and Zucca, E. and Illerhaus, G.
Leukemia 36 (7): 1870-1878. July 2022

R-spondin-YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.
Fischer, A.S. and Müllerke, S. and Arnold, A. and Heuberger, J. and Berger, H. and Lin, M. and Mollenkopf, H.J. and Wizenty, J. and Horst, D. and Tacke, F. and Sigal, M.
Journal of Clinical Investigation 132 (21): e151363. 1 November 2022

Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC.
Fiskin, E. and Lareau, C.A. and Ludwig, L.S. and Eraslan, G. and Liu, F. and Ring, A.M. and Xavier, R.J. and Regev, A.
Nature Biotechnology 40 (3): 374-381. March 2022

Presurgical thalamus volume in postoperative delirium: a longitudinal observational cohort study in older patients.
Fislage, M. and Feinkohl, I. and Pischon, T. and Spies, C.D. and Borchers, F. and Winterer, G. and Zacharias, N.
Anesthesia and Analgesia 135 (1): 136-142. July 2022

Presurgical diffusion metrics of the thalamus and thalamic nuclei in postoperative delirium: a prospective two-centre cohort study in older patients.
Fislage, M. and Winzeck, S. and Stamatakis, E. and Correia, M.M. and Preller, J. and Feinkohl, I. and Spies, C.D. and Hendrikse, J. and J.C Slooter, A. and Winterer, G. and Pischon, T. and Menon, D.K. and Zacharias, N.
NeuroImage: Clinical 36 : 103208. 2022

Subcortical volumes as early predictors of fatigue in multiple sclerosis.
Fleischer, V. and Ciolac, D. and Gonzalez-Escamilla, G. and Grothe, M. and Strauss, S. and Molina Galindo, L.S. and Radetz, A. and Salmen, A. and Lukas, C. and Klotz, L. and Meuth, S.G. and Bayas, A. and Paul, F. and Hartung, H.P. and Heesen, C. and Stangel, M. and Wildemann, B. and Bergh, F.T. and Tackenberg, B. and Kümpfel, T. and Zettl, U.K. and Knop, M. and Tumani, H. and Wiendl, H. and Gold, R. and Bittner, S. and Zipp, F. and Groppa, S. and Muthuraman, M.
Annals of Neurology 91 (2): 192-202. February 2022

Differentiation of cerebral neoplasms with vessel size imaging (VSI).
Foda, A. and Kellner, E. and Gunawardana, A. and Gao, X. and Janz, M. and Kufner, A. and Khalil, A.A. and Geran, R. and Mekle, R. and Fiebach, J.B. and Galinovic, I.
Clinical Neuroradiology 32 (1): 239-248. March 2022

Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised, controlled, open-label, phase 3b trial.
Foley, J.F. and Defer, G. and Ryerson, L.Z. and Cohen, J.A. and Arnold, D.L. and Butzkueven, H. and Cutter, G. and Giovannoni, G. and Killestein, J. and Wiendl, H. and Smirnakis, K. and Xiao, S. and Kong, G. and Kuhelj, R. and Campbell, N.
Lancet Neurology 21 (7): 608-619. July 2022

Therapy switches in fingolimod-treated patients with multiple sclerosis: long-term experience from the German MS Registry.
Frahm, N. and Fneish, F. and Ellenberger, D. and Flachenecker, P. and Paul, F. and Warnke, C. and Kleinschnitz, C. and Parciak, T. and Krefting, D. and Hellwig, K. and Haas, J. and Rommer, P.S. and Stahmann, A. and Zettl, U.K.
Neurology and Therapy 11 (1): 319–336. March 2022

The SCF/KIT axis in human mast cells: capicua acts as potent KIT repressor and ERK predominates PI3K.
Franke, K. and Kirchner, M. and Mertins, P. and Zuberbier, T. and Babina, M.
Allergy 77 (11): 3337-3349. November 2022

Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model.
Freitag, K. and Sterczyk, N. and Wendlinger, S. and Obermayer, B. and Schulz, J. and Farztdinov, V. and Mülleder, M. and Ralser, M. and Houtman, J. and Fleck, L. and Braeuning, C. and Sansevrino, R. and Hoffmann, C. and Milovanovic, D. and Sigrist, S.J. and Conrad, T. and Beule, D. and Heppner, F.L. and Jendrach, M.
Journal of Neuroinflammation 19 (1): 172. 2 July 2022

Kardiomyopathie im Neugeborenenalter: Forschungsfortschritte eröffnen neue diagnostische Möglichkeiten [Cardiomyopathy in neonatal age: advances in research open up new diagnostic possibilities].
Frenzel, M. and Klaassen, S. and Klingel, K. and Knirsch, W. and Kretschmar, O. and Kühnisch, J. and Oxenius, A.
Monatsschrift Kinderheilkunde 170 : 912–916. October 2022

Analysis of adherent cell culture lysates with low metabolite concentrations using the Biocrates AbsoluteIDQ p400 HR kit.
Fritsche-Guenther, R. and Gloaguen, Y. and Eisenberger, A. and Kirwan, J.A.
Scientific Reports 12 (1): 7933. 13 May 2022

Microbiome and metabolome features of the cardiometabolic disease spectrum.
Fromentin, S. and Forslund, S.K. and Chechi, K. and Aron-Wisnewsky, J. and Chakaroun, R. and Nielsen, T. and Tremaroli, V. and Ji, B. and Prifti, E. and Myridakis, A. and Chilloux, J. and Andrikopoulos, P. and Fan, Y. and Olanipekun, M.T. and Alves, R. and Adiouch, S. and Bar, N. and Talmor-Barkan, Y. and Belda, E. and Caesar, R. and Coelho, L.P. and Falony, G. and Fellahi, S. and Galan, P. and Galleron, N. and Helft, G. and Hoyles, L. and Isnard, R. and Le Chatelier, E. and Julienne, H. and Olsson, L. and Pedersen, H.K. and Pons, N. and Quinquis, B. and Rouault, C. and Roume, H. and Salem, J.E. and Schmidt, T.S.B. and Vieira-Silva, S. and Li, P. and Zimmermann-Kogadeeva, M. and Lewinter, C. and Søndertoft, N.B. and Hansen, T.H. and Gauguier, D. and Gøtze, J.P. and Køber, L. and Kornowski, R. and Vestergaard, H. and Hansen, T. and Zucker, J.D. and Hercberg, S. and Letunic, I. and Bäckhed, F. and Oppert, J.M. and Nielsen, J. and Raes, J. and Bork, P. and Stumvoll, M. and Segal, E. and Clément, K. and Dumas, M.E. and Ehrlich, S.D. and Pedersen, O.
Nature Medicine 28 (2): 303-314. 17 February 2022

CTGF/CCN2 has a possible detrimental role in the inflammation and the remyelination failure in the early stages of multiple sclerosis.
Fuchs, L. and Mausner-Fainberg, K. and Luban, A. and Asseyer, S.E. and Golan, M. and Benhamou, M. and Volovitz, I. and Regev, K. and Vigiser, I. and Piura, Y. and Kolb, H. and Paul, F. and Karni, A.
Journal of Neuroimmunology 371 : 577936. 15 October 2022

A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts.
Gabelich, J.A. and Grützke, J. and Kirscht, F. and Popp, O. and Matz, J.M. and Dittmar, G. and Rug, M. and Ingmundson, A.
PLoS Pathogens 18 (9): e1010846. 20 September 2022

PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.
Garces de Los Fayos Alonso, I. and Zujo, L. and Wiest, I. and Kodajova, P. and Timelthaler, G. and Edtmayer, S. and Zrimšek, M. and Kollmann, S. and Giordano, C. and Kothmayer, M. and Neubauer, H.A. and Dey, S. and Schlederer, M. and Schmalzbauer, B.S. and Limberger, T. and Probst, C. and Pusch, O. and Högler, S. and Tangermann, S. and Merkel, O. and Schiefer, A.I. and Kornauth, C. and Prutsch, N. and Zimmerman, M. and Abraham, B. and Anagnostopoulos, J. and Quintanilla-Martinez, L. and Mathas, S. and Wolf, P. and Stoiber, D. and Staber, P.B. and Egger, G. and Klapper, W. and Woessmann, W. and Look, T.A. and Gunning, P. and Turner, S.D. and Moriggl, R. and Lagger, S. and Kenner, L.
Molecular Cancer 21 (1): 172. 31 August 2022

Identification and validation of small molecule analytes in mouse plasma by liquid chromatography–tandem mass spectrometry: A case study of misidentification of a short-chain fatty acid with a ketone body.
García-Rivera, Mariel A. and Fernández-Ochoa, Á. and Brüning, U. and Fritsche-Guenther, R. and Kirwan, J.A.
Talanta 242 : 123298. 15 May 2022

The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.
Garipler, G. and Lu, C. and Morrissey, Al. and Lopez-Zepeda, L.S. and Pei, Y. and Vidal, S.E. and Zen Petisco Fiore, A.P. and Aydin, B. and Stadtfeld, M. and Ohler, U. and Mahony, S. and Sanjana, N.E. and Mazzoni, E.O.
Cell Reports 38 (11): 110524. 15 March 2022

IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis.
Garnier, L. and Pick, R. and Montorfani, J. and Sun, M. and Brighouse, D. and Liaudet, N. and Kammertoens, T. and Blankenstein, T. and Page, N. and Bernier-Latamani, J. and Tran, N.L. and Petrova, T.V. and Merkler, D. and Scheiermann, C. and Hugues, S.
Science Advances 8 (23): eabl5162. 8 June 2022

Hypertension in pregnancy: diagnosis, blood pressure goals, and pharmacotherapy: a scientific statement from the American Heart Association.
Garovic, V.D. and Dechend, R. and Easterling, T. and Karumanchi, S.A. and McMurtry Baird, S. and Magee, L.A. and Rana, S. and Vermunt, J.V. and August, P.
Hypertension 79 (2): e21-e41. February 2022

Bruton's tyrosine kinase inhibitors in multiple sclerosis: pioneering the path towards treatment of progression?
Geladaris, A. and Torke, S. and Weber, M.S.
CNS drugs 36 (10): 1019-1030. October 2022

Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg, P. and Astaburuaga-García, R. and Bonaguro, L. and Brumhard, S. and Michalick, L. and Lippert, L.J. and Kostevc, T. and Gäbel, C. and Schneider, M. and Streitz, M. and Demichev, V. and Gemünd, I. and Barone, M. and Tober-Lau, P. and Helbig, E.T. and Hillus, D. and Petrov, L. and Stein, J. and Dey, H.P. and Paclik, D. and Iwert, C. and Mülleder, M. and Aulakh, S.K. and Djudjaj, S. and Bülow, R.D. and Mei, H.E. and Schulz, A.R. and Thiel, A. and Hippenstiel, S. and Saliba, A.E. and Eils, R. and Lehmann, I. and Mall, M.A. and Stricker, S. and Röhmel, J. and Corman, V.M. and Beule, D. and Wyler, E. and Landthaler, M. and Obermayer, B. and von Stillfried, S. and Boor, P. and Demir, M. and Wesselmann, H. and Suttorp, N. and Uhrig, A. and Müller-Redetzky, H. and Nattermann, J. and Kuebler, W.M. and Meisel, C. and Ralser, M. and Schultze, J.L. and Aschenbrenner, A.C. and Thibeault, C. and Kurth, F. and Sander, L.E. and Blüthgen, N. and Sawitzki, B.
Cell 185 (3): 493-512. 3 February 2022

The role of intraspinal sensory neurons in the control of quadrupedal locomotion.
Gerstmann, K. and Jurčić, N. and Blasco, E. and Kunz, S. and de Almeida Sassi, F. and Wanaverbecq, N. and Zampieri, N.
Current Biology 32 (11): 2442-2453. 6 June 2022

Improving robustness of automatic cardiac function quantification from cine magnetic resonance imaging using synthetic image data.
Gheorghiță, B.A. and Itu, L.M. and Sharma, P. and Suciu, C. and Wetzl, J. and Geppert, C. and Ali, M.A.A. and Lee, A.M. and Piechnik, S.K. and Neubauer, S. and Petersen, S.E. and Schulz-Menger, J. and Chițiboi, T.
Scientific Reports 12 (1): 2391. 14 February 2022

Isotopic tracing of glucose metabolites in human monocytes to assess changes in inflammatory conditions.
Giacomello, G. and Böttcher, C. and Parr, M.K.
STAR Protocols 3 (4): 101715. 16 December 2022

Structure-function correlates of vision loss in neuromyelitis optica spectrum disorders.
Gigengack, N.K. and Oertel, F.C. and Motamedi, S. and Bereuter, C. and Duchow, A. and Rust, R. and Bellmann‑Strobl, J. and Ruprecht, K. and Schmitz-Hübsch, T. and Paul, F. and Brandt, A.U. and Zimmermann, H.G.
Scientific Reports 12 (1): 17545. 20 October 2022

Aging-regulated TUG1 is dispensable for endothelial cell function.
Gimbel, A.T. and Koziarek, S. and Theodorou, K. and Schulz, J.F. and Stanicek, L. and Kremer, V. and Ali, T. and Günther, S. and Kumar, S. and Jo, H. and Hübner, N. and Maegdefessel, L. and Dimmeler, S. and van Heesch, S. and Boon, R.A.
PLoS ONE 17 (9): e0265160. 29 September 2022

Rapid inflammasome activation is attenuated in post-myocardial infarction monocytes.
Giral, H. and Franke, V. and Moobed, M. and Müller, M.F. and Lübking, L. and James, D.M. and Hartung, J. and Kuschnerus, K. and Meteva, D. and Seppelt, C. and Jakob, P. and Klingenberg, R. and Kränkel, N. and Leistner, D. and Zeller, T. and Blankenberg, S. and Zimmermann, F. and Haghikia, A. and Lüscher, T.F. and Akalin, A. and Landmesser, U. and Kratzer, A.
Frontiers in Immunology 13 : 857455. 26 April 2022

Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus.
Gjaltema, R.A.F. and Schwämmle, T. and Kautz, P. and Robson, M. and Schöpflin, R. and Ravid Lustig, L. and Brandenburg, L. and Dunkel, I. and Vechiatto, C. and Ntini, E. and Mutzel, V. and Schmiedel, V. and Marsico, A. and Mundlos, S. and Schulz, E.G.
Molecular Cell 82 (1): 190-208.e17. 6 January 2022

Deep learning-assisted peak curation for large-scale LC-MS metabolomics.
Gloaguen, Y. and Kirwan, J.A. and Beule, D.
Analytical Chemistry 94 (12): 4930-4937. 29 March 2022

An unusual aspartic acid cluster in the reovirus attachment fiber s1 mediates stability at low pH and preserves trimeric organization.
Glorani, G. and Ruwolt, M. and Holton, N. and Loll, B. and Neu, U.
Journal of Virology 96 (8): e0033122. April 2022

Every islet matters: improving the impact of human islet research.
Gloyn, Anna L and Ibberson, Mark and Marchetti, Piero and Powers, Alvin C and Rorsman, Patrik and Sander, M. and Solimena, Michele
Nature Metabolism 4 (8): 970-977. August 2022

Fluorescence spectroscopy of low-level endogenous β-adrenergic receptor expression at the plasma membrane of differentiating human iPSC-derived cardiomyocytes.
Gmach, P. and Bathe-Peters, M. and Telugu, N. and Miller, D.C. and Annibale, P.
International Journal of Molecular Sciences 23 (18): 10405. 8 September 2022

Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O. and Zincke, F. and Eckert, A. and Kobelt, D. and Preissner, S. and Liebeskind, J.M. and Gunkel, N. and Putzker, K. and Lewis, J. and Preissner, S. and Kortüm, B. and Walther, W. and Mura, K. and Bourne, P.E. and Stein, U. and Preissner, R.
Clinical and Translational Medicine 12 (2): e726. 20 February 2022

Expression of circ_Satb1 is decreased in mesial temporal lobe epilepsy and regulates dendritic spine morphology.
Gomes-Duarte, A. and Venø, M.T. and de Wit, M. and Senthilkumar, K. and Broekhoven, M.H. and van den Herik, J. and Heeres, F.R. and van Rossum, D. and Rybiczka-Tesulov, M. and Legnini, I. and van Rijen, P.C. and van Eijsden, P. and Gosselaar, P.H. and Rajewsky, N. and Kjems, J. and Vangoor, V.R. and Pasterkamp, R.J.
Frontiers in Molecular Neuroscience 15 : 832133. 3 March 2022

Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension.
Grabowski, K. and Herlan, L. and Witten, A. and Qadri, F. and Eisenreich, A. and Lindner, D. and Schädlich, M. and Schulz, A. and Subrova, J. and Mhatre, K.N. and Primessnig, U. and Plehm, R. and van Linthout, S. and Escher, F. and Bader, M. and Stoll, M. and Westermann, D. and Heinzel, F.R. and Kreutz, R.
Hypertension Research 45 : 292-307. January 2022

Preclinical testing of dendritic core-multishell nanoparticles in inflammatory skin equivalents.
Graff, P. and Hönzke, S. and Joshi, A.A. and Yealland, G. and Fleige, E. and Unbehauen, M. and Schäfer-Korting, M. and Hocke, A. and Haag, R. and Hedtrich, S.
Molecular Pharmaceutics 19 (6): 1795-1802. 6 June 2022

The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S. and Cabantog, A. and MacPhee, L. and Im, J. and Ruess, C. and Demir, B. and Sperb, N. and Rücker, F.G. and Döhner, K. and Herold, T. and Pollack, J.R. and Bullinger, L. and Rouhi, A. and Kuchenbauer, F.
Haematologica 107 (8): 1758-1772. August 2022

Age of red cells for transfusion and outcomes in patients with ARDS.
Graw, J.A. and Bünger, V. and Materne, L.A. and Krannich, A. and Balzer, F. and Francis, R.C.E. and Pruß, A. and Spies, C.D. and Kuebler, W.M. and Weber-Carstens, S. and Menk, M. and Hunsicker, O.
Journal of Clinical Medicine 11 (1): 245. 4 January 2022

Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.
Greco, T.M. and Secker, C. and Silva Ramos, E. and Federspiel, J.D. and Liu, J.P. and Perez, A.M. and Al-Ramahi, I. and Cantle, J.P. and Carroll, J.B. and Botas, J. and Zeitlin, S.O. and Wanker, E.E. and Cristea, I.M.
Cell Systems 13 (4): 304-320.e5. 22 April 2022

Was ist gesichert in der Therapie der chronischen Nierenerkrankung? [What is confirmed in the treatment of chronic kidney disease?].
Greite, R. and Schmidt-Ott, K.
Innere Medizin 63 (12): 237-1243. December 2022

Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.
Grinat, J. and Kosel, F. and Goveas, N. and Kranz, A. and Alexopoulou, D. and Rajewsky, K. and Sigal, M. and Stewart, A.F. and Heuberger, J.
Life Science Alliance 5 (4): e202101187. April 2022

Influence of nanogel amphiphilicity on dermal delivery: balancing surface hydrophobicity and network rigidity.
Gruber, Al. and Joshi, A.A. and Graff, P. and Cuéllar-Camacho, J.L. and Hedtrich, S. and Klinger, D.
Biomacromolecules 23 (1): 112-127. 10 January 2022

Isolation of neoantigen-specific human T cell receptors from different human and murine repertoires.
Grunert, C. and Willimsky, G. and Peuker, C.A. and Rhein, S. and Hansmann, L. and Blankenstein, T. and Blanc, E. and Beule, D. and Keller, U. and Pezzutto, A. and Busse, A.
Cancers 14 (7): 1842. 6 April 2022

Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients.
Grunow, J.J. and Reiher, K. and Carbon, N.M. and Engelhardt, L.J. and Mai, K. and Koch, S. and Schefold, J.C. and Z'Graggen, W. and Schaller, S.J. and Fielitz, J. and Spranger, J. and Weber-Carstens, S. and Wollersheim, T.
Critical Care 26 (1): 237. 3 August 2022

Statins aggravate the risk of insulin resistance in human muscle.
Grunwald, S.A. and Haafke, S. and Grieben, U. and Kassner, U. and Steinhagen-Thiessen, E. and Spuler, S.
International Journal of Molecular Sciences 23 (4): 2398. 21 February 2022

Fast acquisition of left and right ventricular function parameters applying cardiovascular magnetic resonance in clinical routine - validation of a 2-shot compressed sensing cine sequence.
Gröschel, J. and Ammann, C. and Zange, L. and Viezzer, D. and Forman, C. and Schmidt, M. and Blaszczyk, E. and Schulz-Menger, J.
Scandinavian Cardiovascular Journal 56 (1): 266-275. 14 July 2022

Different impacts on the heart after COVID-19 infection and vaccination: insights from cardiovascular magnetic resonance.
Gröschel, J. and Bhoyroo, Y. and Blaszczyk, E. and Trauzeddel, R.F. and Viezzer, D. and Saad, H. and Fenski, M. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 9 : 916922. 14 July 2022

Cell-type specific inhibition controls the high-frequency oscillations in the medial entorhinal cortex.
Gurgenidze, S. and Bäuerle, P. and Schmitz, D. and Vida, I. and Gloveli, T. and Dugladze, T.
International Journal of Molecular Sciences 23 (22): 14087. 15 November 2022

Phenotypic spectrum of BLM- and RMI1-related Bloom syndrome.
Gönenc, I.I. and Elcioglu, N.H. and Martinez Grijalva, C. and Aras, S. and Großmann, N. and Praulich, I. and Altmüller, J. and Kaulfuß, S. and Li, Y. and Nürnberg, P. and Burfeind, P. and Yigit, G. and Wollnik, B.
Clinical Genetics 101 (5-6): 559-564. May 2022

MACC1-dependent antitumor effect of curcumin in colorectal cancer.
Güllü, N. and Smith, J. and Herrmann, P. and Stein, U.
Nutrients 14 (22): 4792. 12 November 2022

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel, G. and Conlon, T.M. and Jeridi, A. and Kim, R. and Ertüz, Z. and Lang, N.J. and Ansari, M. and Novikova, M. and Jiang, D. and Strunz, M. and Gaianova, M. and Hollauer, C. and Gabriel, C. and Angelidis, I. and Doll, S. and Pestoni, J.C. and Edelmann, S.L. and Kohlhepp, M.S. and Guillot, A. and Bassler, K. and Van Eeckhoutte, H.P. and Kayalar, Ö. and Konyalilar, N. and Kanashova, T. and Rodius, S. and Ballester-López, C. and Genes Robles, C.M. and Smirnova, N. and Rehberg, M. and Agarwal, C. and Krikki, I. and Piavaux, B. and Verleden, S.E. and Vanaudenaerde, B. and Königshoff, M. and Dittmar, G. and Bracke, K.R. and Schultze, J.L. and Watz, H. and Eickelberg, O. and Stoeger, T. and Burgstaller, G. and Tacke, F. and Heissmeyer, V. and Rinkevich, Y. and Bayram, H. and Schiller, H.B. and Conrad, M. and Schneider, R. and Yildirim, A.Ö.
Nature Communications 13 (1): 1303. 14 March 2022

A molecularly characterized preclinical platform of subcutaneous renal cell carcinoma (RCC) patient-derived xenograft models to evaluate novel treatment strategies.
Gürgen, D. and Becker, M. and Dahlmann, M. and Flechsig, S. and Schaeffeler, E. and Büttner, F.A. and Schmees, C. and Bohnert, R. and Bedke, J. and Schwab, M. and Wendler, J.J. and Schostak, M. and Jandrig, B. and Walther, W. and Hoffmann, J.
Frontiers in Oncology 12 : 889789. 21 June 2022

Lösliche Guanylatzyklase(sGC)-Stimulation mit Vericiguat: Von der pharmakologischen Idee bis zur Therapie der chronischen Herzinsuffizienz [Soluble guanylate cyclase (sGC) stimulation with vericiguat : from the pharmacological idea to the treatment of chronic heart failure].
Haase, N. and Kedziora, S.M. and Mueller, D.N. and Dechend, R.
Kardiologie 16 (6): 466-478. December 2022

Introduction of Lazy Luna an automatic software-driven multilevel comparison of ventricular function quantification in cardiovascular magnetic resonance imaging.
Hadler, T. and Wetzl, J. and Lange, S. and Geppert, C. and Fenski, M. and Abazi, E. and Gröschel, J. and Ammann, C. and Wenson, F. and Töpper, A. and Däuber, S. and Schulz-Menger, J.
Scientific Reports 12 (1): 6629. 22 April 2022

Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats.
Haduch, A. and Danek, P.J. and Kuban, W. and Pukło, R. and Alenina, N. and Gołębiowska, J. and Popik, P. and Bader, M. and Daniel, W.A.
Neurochemistry International 152 : 105223. January 2022

Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS).
Haffke, M. and Freitag, H. and Rudolf, G. and Seifert, M. and Doehner, W. and Scherbakov, N. and Hanitsch, L. and Wittke, K. and Bauer, S. and Konietschke, F. and Paul, F. and Bellmann-Strobl, J. and Kedor, C. and Scheibenbogen, C. and Sotzny, F.
Journal of Translational Medicine 20 (1): 138. 22 March 2022

miR-142 favors naïve B cell residence in peripheral lymph nodes.
Hagen, M. and Chakraborty, T. and Olson, W.J. and Heitz, M. and Hermann-Kleiter, N. and Kimpel, J. and Jenewein, B. and Pertoll, J. and Labi, V. and Rajewsky, K. and Derudder, E.
Frontiers in Immunology 13 : 847415. 10 November 2022

Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism.
Haghikia, A. and Zimmermann, F. and Schumann, P. and Jasina, A. and Roessler, J. and Schmidt, D. and Heinze, P. and Kaisler, J. and Nageswaran, V. and Aigner, A. and Ceglarek, U. and Cineus, R. and Hegazy, A.N. and van der Vorst, E.P.C. and Döring, Y. and Strauch, C.M. and Nemet, I. and Tremaroli, V. and Dwibedi, C. and Kränkel, N. and Leistner, D.M. and Heimesaat, M.M. and Bereswill, S. and Rauch, G. and Seeland, U. and Soehnlein, O. and Müller, D.N. and Gold, R. and Bäckhed, F. and Hazen, S.L. and Haghikia, A. and Landmesser, U.
European Heart Journal 43 (6): ehab644. 7 February 2022

An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
Hahn, T. and Ernsting, J. and Winter, N.R. and Holstein, V. and Leenings, R. and Beisemann, M. and Fisch, L. and Sarink, K. and Emden, D. and Opel, N. and Redlich, R. and Repple, J. and Grotegerd, D. and Meinert, S. and Hirsch, J.G. and Niendorf, T. and Endemann, B. and Bamberg, F. and Kröncke, T. and Bülow, R. and Völzke, H. and von Stackelberg, O. and Sowade, R.F. and Umutlu, L. and Schmidt, B. and Caspers, S. and Kugel, H. and Kircher, T. and Risse, B. and Gaser, C. and Cole, J.H. and Dannlowski, U. and Berger, K.
Science Advances 8 (1): eabg9471. 7 January 2022

Long-term connectome analysis reveals reshaping of visual, spatial networks in a model with vascular dementia features.
Hall, G.R. and Boehm-Sturm, P. and Dirnagl, U. and Finke, C. and Foddis, M. and Harms, C. and Koch, S.P. and Kuchling, J. and Madan, C.R. and Mueller, S. and Sassi, C. and Sotiropoulos, S.N. and Trueman, R.C. and Wallis, M.D. and Yildirim, F. and Farr, T.D.
Stroke 53 (5): 1735-1745. May 2022

Rational design of highly potent, selective, and bioavailable SGK1 protein kinase inhibitors for the treatment of osteoarthritis.
Halland, N. and Schmidt, F. and Weiss, T. and Li, Z. and Czech, J. and Saas, J. and Ding-Pfennigdorff, D. and Dreyer, M.K. and Strübing, C. and Nazare, M.
Journal of Medicinal Chemistry 65 (2): 1567-1584. 27 January 2022

A comparative study of graph matching algorithms in computer vision.
Haller, S. and Feineis, L. and Hutschenreiter, L. and Bernard, F. and Rother, C. and Kainmüller, D. and Swoboda, P. and Savchynskyy, B.
Lecture Notes in Computer Science 13683 : 636-653. 2022

High-resolution transthoracic echocardiography accurately detects pulmonary arterial pressure and decreased right ventricular contractility in a mouse model of pulmonary fibrosis and secondary pulmonary hypertension.
Hansen, T.S. and Bubb, K.J. and Schiattarella, G.G. and Ugander, M. and Tan, T.C. and Figtree, G.A.
Journal of the American Heart Association 11 (23): e018353. 6 December 2022

A critical period of translational control during brain development at codon resolution.
Harnett, D. and Ambrozkiewicz, M.C. and Zinnall, U. and Rusanova, A. and Borisova, E. and Drescher, A.N. and Couce-Iglesias, M. and Villamil, G. and Dannenberg, R. and Imami, K. and Münster-Wandowski, A. and Fauler, B. and Mielke, T. and Selbach, M. and Landthaler, M. and Spahn, C.M.T. and Tarabykin, V. and Ohler, U. and Kraushar, M.L.
Nature Structural & Molecular Biology 29 (12): 1277-1290. December 2022

Sensitivity and specificity of loss of heterozygosity analysis for the classification of rare germline variants in BRCA1/2: results of the observational AGO-TR1 study (NCT02222883).
Hauke, J. and Harter, P. and Ernst, C. and Burges, A. and Schmidt, S. and Reuss, A. and Borde, J. and De Gregorio, N. and Dietrich, D. and El-Balat, A. and Kayali, M. and Gevensleben, H. and Hilpert, F. and Altmüller, J. and Heimbach, A. and Meier, W. and Schoemig-Markiefka, B. and Thiele, H. and Kimmig, R. and Nürnberg, P. and Kast, K. and Richters, L. and Sehouli, J. and Schmutzler, R.K. and Hahnen, E.
Journal of Medical Genetics 59 (3): 248-252. March 2022

Widely applicable, extended flow cytometric stem cell enumeration panel for quality control of advanced cellular products.
Haussmann, K. and Streitz, M. and Takvorian, A. and Grund, J. and Skenderi, Z. and Tietze-Bürger, C. and Movassaghi, K. and Künkele, A. and Blum, A. and Bullinger, L.
Scientific Reports 12 (1): 17995. 26 October 2022

Robust induction of primordial germ cells of white rhinoceros on the brink of extinction.
Hayashi, M. and Zywitza, V. and Naitou, Y. and Hamazaki, N. and Goeritz, F. and Hermes, R. and Holtze, S. and Lazzari, G. and Galli, C. and Stejskal, J. and Diecke, S. and Hildebrandt, T.B. and Hayashi, K.
Science Advances 8 (49): eabp9683. 9 December 2022

Pseudocholinesterase as a biomarker for untreated Wilson's disease.
Hefter, H. and Arslan, M. and Kruschel, T.S. and Novak, M. and Rosenthal, D. and Meuth, S.G. and Albrecht, P. and Hartmann, C.J. and Samadzadeh, S.
Biomolecules 12 (12): 1791. December 2022

Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia.
Hegazy, A.N. and Krönke, J. and Angermair, S. and Schwartz, S. and Weidinger, C. and Keller, U. and Treskatsch, S. and Siegmund, B. and Schneider, T.
BMC Infectious Diseases 22 (1): 537. 13 June 2022

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool.
Hernández-Malmierca, P. and Vonficht, D. and Schnell, A. and Uckelmann, H.J. and Bollhagen, A. and Mahmoud, M.A.A. and Landua, S.L. and van der Salm, E. and Trautmann, C. and Raffel, S. and Grünschläger, F. and Lutz, R. and Ghosh, M. and Renders, S. and Correia, N. and Donato, E. and Dixon, K.O. and Hirche, C. and Andresen, C. and Robens, Cl. and Werner, P.S. and Boch, T. and Eisel, D. and Osen, W. and Pilz, F. and Przybylla, A. and Klein, C. and Buchholz, F. and Milsom, M.D. and Essers, M.A.G. and Eichmüller, S.B. and Hofmann, W.K. and Nowak, D. and Hübschmann, D. and Hundemer, M. and Thiede, C. and Bullinger, L. and Müller-Tidow, C. and Armstrong, S.A. and Trumpp, A. and Kuchroo, V.K. and Haas, S.
Cell Stem Cell 29 (5): 760-775. 5 May 2022

In vivo stiffness of multiple sclerosis lesions is similar to that of normal-appearing white matter.
Herthum, H. and Hetzer, S. and Scheel, M. and Shahryari, M. and Braun, J. and Paul, F. and Sack, I.
Acta Biomaterialia 138 : 410-421. 15 January 2022

A phase II trial to evaluate the combination of pixantrone and obinutuzumab for patients with relapsed aggressive lymphoma: Final results of the prospective, multicentre GOAL trial.
Hess, G. and Hüttmann, A. and Witzens-Harig, M. and Dreyling, M.H. and Keller, U. and Marks, R. and Ernst, T. and Pott, C. and Viardot, A. and Frontzek, F. and Trautmann, M. and Ruckes, C. and Deuster, O. and Rosenwald, A. and Theobald, M. and Lenz, G.
British Journal of Haematology 198 (3): 482-491. 1 April 2022

Temperature elevations can induce switches to homoclinic action potentials that alter neural encoding and synchronization.
Hesse, J. and Schleimer, J.H. and Maier, N. and Schmitz, D. and Schreiber, S.
Nature Communications 13 (1): 3934. 8 July 2022

Locus-conserved circular RNA cZNF292 controls endothelial cell flow responses.
Heumüller, A.W. and Jones, A. N. and Mourão, A. and Klangwart, M. and Shi, C. and Wittig, I. and Fischer, A. and Muhly Reinholz, M. and Buchmann, G.K. and Dieterich, C. and Potente, M. and Braun, T. and Grote, P. and Jaé, N. and Sattler, M. and Dimmeler, S.
Circulation Research 130 (1): 67-79. 7 January 2022

Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors.
Heynen, G.J.J.E. and Lisek, K. and Vogel, R. and Wulf-Goldenberg, A. and Alcaniz, J. and Montaudon, E. and Marangoni, E. and Birchmeier, W.
Breast Cancer Research 24 (1): 23. 1 April 2022

Inflammation and convergent placenta gene co-option contributed to a novel reproductive tissue.
Hilgers, L. and Roth, O. and Nolte, A.W. and Schüller, A. and Spanke, T. and Flury, J.M. and Utama, I.V. and Altmüller, J. and Wowor, D. and Misof, B. and Herder, F. and Böhne, A. and Schwarzer, J.
Current Biology 32 (3): 715-724. 7 February 2022

Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury.
Hinze, C. and Kocks, C. and Leiz, J. and Karaiskos, N. and Boltengagen, A. and Cao, S. and Skopnik, C.M. and Klocke, J. and Hardenberg, J.H. and Stockmann, H. and Gotthardt, I. and Obermayer, B. and Haghverdi, L. and Wyler, E. and Landthaler, M. and Bachmann, S. and Hocke, A.C. and Corman, V. and Busch, J. and Schneider, W. and Himmerkus, N. and Bleich, M. and Eckardt, K.U. and Enghard, P. and Rajewsky, N. and Schmidt-Ott, K.M.
Genome Medicine 14 (1): 103. 9 September 2022

Tracking by weakly-supervised learning and graph optimization for whole-embryo c. elegans lineages.
Hirsch, P. and Malin-Mayor, C. and Santella, A. and Preibisch, S. and Kainmueller, D. and Funke, J.
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Uncoupling the excitatory amino acid transporter 2 from its C-terminal interactome restores synaptic glutamate clearance at corticostriatal synapses and alleviates mutant huntingtin-induced hypokinesia.
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Protocol for fast scRNA-seq raw data processing using scKB and non-arbitrary quality control with COPILOT.
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Nature Genetics 54 (8): 1227-1237. August 2022

Calorie restriction enhanced glycogen metabolism to compensate for lipid insufficiency.
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Molecular Nutrition & Food Research 66 (20): 2200182. October 2022

Microglia/macrophage derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model.
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Cell Reports 39 (2): 110670. 12 April 2022

Rationale and design of the prevention of paclitaxel-related neurological side effects with lithium trial – Protocol of a multicenter, randomized, double-blind, placebo-controlled proof-of-concept phase-2 clinical trial.
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3D model-based super-resolution motion-corrected cardiac T1 mapping.
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Women in the European Virus Bioinformatics Center.
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Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
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Nature Genetics 54 (11): 1746–1754. November 2022

CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage.
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Journal of Neuroinflammation 19 (1): 86. 12 April 2022

Physical performance and non-esterified fatty acids in men and women after transcatheter aortic valve implantation (TAVI).
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Nutrients 14 (1): 203. 2 January 2022

Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.
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European Respiratory Journal 60 (6): 2102725. 1 December 2022

Evaluation of pharmacological rescue of melanocortin-4 receptor nonsense mutations by aminoglycoside.
Höpfner, F. and Paisdzior, S. and Reininghaus, N. and Sohail, I. and Scheerer, P. and Annibale, P. and Biebermann, H. and Kühnen, P.
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Costs and health-related quality of life in patients with NMO spectrum disorders and MOG-antibody-associated disease: CHANCE(NMO) study.
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Neurology 98 (11): e1184-e1196. 15 March 2022

Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy.
Ihlow, J. and Gross, S. and Busack, L. and Flörcken, A. and Jesse, J. and Schwarz, M. and Neuendorff, N.R. and von Brünneck, A.C. and Anagnostopoulos, I. and Türkmen, S. and Blau, I.W. and Burmeister, T. and Horst, D. and Bullinger, L. and Westermann, J.
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Automated detection and localization of synaptic vesicles in electron microscopy images.
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eNeuro 9 (1): ENEURO.0400-20.2021. January 2022

H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2(+) patients with diffuse midline glioma.
Immisch, L. and Papafotiou, G. and Popp, O. and Mertins, P. and Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 10 (10): e005535. 27 October 2022

Dynamics of bacteria scanning a porous environment.
Irani, E. and Mokhtari, Z. and Zippelius, A.
Physical Review Letters 128 (14): 144501. 5 April 2022

Analyses of circRNA expression throughout the light-dark cycle reveal a strong regulation of (Cdr1as), associated with light entrainment in the SCN.
Ivanov, A. and Mattei, D. and Radscheit, K. and Compagnion, A.C. and Pett, J.P. and Herzel, H.P. and Paolicelli, R.C. and Piwecka, M. and Meyer, U. and Beule, D.
International Journal of Molecular Sciences 23 (20): 12347. October 2022

Impact of the first COVID-19 lockdown in Germany on the rate of acute infections during intensive chemotherapy for Hodgkin lymphoma.
Jacob, A.S. and Kaul, H. and Fuchs, M. and Gillessen, S. and Kreissl, S. and Pluetschow, A. and Momotow, J. and Schaub, V. and Huettmann, A. and Haenel, M. and Zimmermann, A. and Dierlamm, J. and Meissner, J. and Mathas, S. and Martin, S. and Engert, A. and Hallek, M. and Borchmann, P. and Lehmann, C.
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The bias from heaping on risk estimation: Effect of age at diagnosis of hypertension on risk of subsequent cardiovascular comorbidities.
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Annals of Epidemiology 74 : 84-96. October 2022

Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.
Jahn, N. and Jahn, E. and Saadati, M. and Bullinger, L. and Larson, R.A. and Ottone, T. and Amadori, S. and Prior, T.W. and Brandwein, J.M. and Appelbaum, F.R. and Medeiros, B.C. and Tallman, M.S. and Ehninger, G. and Heuser, M. and Ganser, A. and Pallaud, C. and Gathmann, I. and Krzykalla, J. and Benner, A. and Bloomfield, C.D. and Thiede, C. and Stone, R.M. and Döhner, H. and Döhner, K.
Leukemia 36 (9): 2218-2227. September 2022

Non-redundant functions of group 2 innate lymphoid cells.
Jarick, K.J. and Topczewska, P.M. and Jakob, M.O. and Yano, H. and Arifuzzaman, M. and Gao, X. and Boulekou, S. and Stokic-Trtica, V. and Leclère, P.S. and Preußer, A. and Rompe, Z.A. and Stamm, A. and Tsou, A.M. and Chu, C. and Heinrich, F.R. and Guerra, G.M. and Durek, P. and Ivanov, A. and Beule, D. and Helfrich, S. and Duerr, C.U. and Kühl, A.A. and Stehle, C. and Romagnani, C. and Mashreghi, M.F. and Diefenbach, A. and Artis, D. and Klose, C.S.N.
Nature 611 (7937): 794-800. 24 November 2022

Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients.
Jarius, S. and Pache, F. and Körtvelyessy, P. and Jelčić, I. and Stettner, M. and Franciotta, D. and Keller, E. and Neumann, B. and Ringelstein, M. and Senel, M. and Regeniter, A. and Kalantzis, R. and Willms, J.F. and Berthele, A. and Busch, M. and Capobianco, M. and Eisele, A. and Reichen, I. and Dersch, R. and Rauer, S. and Sandner, K. and Ayzenberg, I. and Gross, C.C. and Hegen, H. and Khalil, M. and Kleiter, I. and Lenhard, T. and Haas, J. and Aktas, O. and Angstwurm, K. and Kleinschnitz, C. and Lewerenz, J. and Tumani, H. and Paul, F. and Stangel, M. and Ruprecht, K. and Wildemann, B.
Journal of Neuroinflammation 19 (1): 19. 20 January 2022

Semi-automated assembly of high-quality diploid human reference genomes.
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Nature 611 (7936): 519-531. 17 November 2022

Efficacy and feasibility of proton beam therapy in relapsed high-risk neuroblastoma-experiences from the prospective KiProReg registry.
Jazmati, D. and Hero, B. and Thole-Kliesch, T.M. and Merta, J. and Deubzer, H.E. and Bäumer, C. and Heinzelmann, F. and Schleithoff, S.S. and Koerber, F. and Eggert, A. and Schwarz, R. and Simon, T. and Timmermann, B.
Current Oncology 29 (11): 8222-8234. November 2022

Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice.
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Scientific Reports 12 (1): 5108. 24 March 2022

Prediction of activity-related energy expenditure under free-living conditions using accelerometer-derived physical activity.
Jeran, S. and Steinbrecher, A. and Haas, V. and Mähler, A. and Boschmann, M. and Westerterp, K.R. and Brühmann, B.A. and Steindorf, K. and Pischon, T.
Scientific Reports 12 (1): 16578. 4 October 2022

Targeting cathepsin C in PR3-ANCA vasculitis.
Jerke, U. and Eulenberg-Gustavus, C. and Rousselle, A. and Nicklin, P. and Kreideweiss, S. and Grundl, M.A. and Eickholz, P. and Nickles, K. and Schreiber, A. and Korkmaz, B. and Kettritz, R.
Journal of the American Society of Nephrology 33 (5): 936-947. May 2022

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Jin, Y. and Ding, Y. and Richards, M. and Kaakinen, M. and Giese, W. and Baumann, E. and Szymborska, A. and Rosa, A. and Nordling, S. and Schimmel, L. and Akmeriç, E.B. and Pena, A. and Nwadozi, E. and Jamalpour, M. and Holstein, K. and Sáinz-Jaspeado, M. and Bernabeu, M.O. and Welsh, M. and Gordon, E. and Franco, C.A. and Vestweber, D. and Eklund, L. and Gerhardt, H. and Claesson-Welsh, L.
Nature Cardiovascular Research 1 (12): 1156–1173. December 2022

Accelerating clinical scale production of BCMA CAR T cells with defined maturation stages.
Joedicke, J.J. and Großkinsky, U. and Gerlach, K. and Künkele, A. and Höpken, U.E. and Rehm, A.
Molecular Therapy - Methods and Clinical Development 24 : 181-198. 10 March 2022

DNA methylation-based classification of sinonasal tumors.
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Nature Communications 13 (1): 7148. 28 November 2022

Cardiac surgery-related acute kidney injury - risk factors, clinical course, management suggestions.
Just, I.A. and Alborzi, F. and Godde, M. and Ott, S. and Meyer, A. and Stein, J. and Mazgareanu, S. and van der Giet, M. and Schmidt-Ott, K.M. and Falk, V. and Schoenrath, F.
Journal of Cardiothoracic and Vascular Anesthesia 36 (2): 444-451. February 2022

A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts.
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Science Advances 8 (33): eabk2814. August 2022

Significant reduced loss of bone mineral density after four vs. six cycles of R-CHOP: an analysis of the FLYER-trial.
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Filaggrin loss-of-function mutations are associated with persistence of egg and milk allergy.
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Tolerance induction through early feeding to prevent food allergy in infants with eczema (TEFFA): rationale, study design, and methods of a randomized controlled trial.
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Serotonin limits generation of chromaffin cells during adrenal organ development.
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Nature Communications 13 (1): 2901. 25 May 2022

(RB1)-negative retinal organoids display proliferation of cone photoreceptors and loss of retinal differentiation.
Kanber, D. and Woestefeld, J. and Döpper, H. and Bozet, M. and Brenzel, A. and Altmüller, J. and Kilpert, F. and Lohmann, D. and Pommerenke, C. and Steenpass, L.
Cancers 14 (9): 2166. 26 April 2022

Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load.
Kaneshige, A. and Kaji, T. and Zhang, L. and Saito, H. and Nakamura, A. and Kurosawa, T. and Ikemoto-Uezumi, M. and Tsujikawa, K. and Seno, S. and Hori, M. and Saito, Y. and Matozaki, T. and Maehara, K. and Ohkawa, Y. and Potente, M. and Watanabe, S. and Braun, T. and Uezumi, A. and Fukada, S.I.
Cell Stem Cell 29 (2): 265-280. 3 February 2022

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.
Kapalczynska, M. and Lin, M. and Maertzdorf, J. and Heuberger, J. and Muellerke, S. and Zuo, X. and Vidal, R. and Shureiqi, I. and Fischer, A.S. and Sauer, S. and Berger, H. and Kidess, E. and Mollenkopf, H.J. and Tacke, F. and Meyer, T.F. and Sigal, M.
Nature Communications 13 (1): 1577. 24 March 2022

Automated imaging-based abdominal organ segmentation and quality control in 20,000 participants of the UK Biobank and German National Cohort Studies.
Kart, T. and Fischer, M. and Winzeck, S. and Glocker, B. and Bai, W. and Bülow, R. and Emmel, C. and Friedrich, L. and Kauczor, H.U. and Keil, T. and Kröncke, T. and Mayer, P. and Niendorf, T. and Peters, A. and Pischon, T. and Schaarschmidt, B.M. and Schmidt, B. and Schulze, M.B. and Umutle, L. and Völzke, H. and Küstner, T. and Bamberg, F. and Schölkopf, B. and Rueckert, D. and Gatidis, S.
Scientific Reports 12 (1): 18733. 4 November 2022

A faecal microbiota signature with high specificity for pancreatic cancer.
Kartal, E. and Schmidt, T.S.B. and Molina-Montes, E. and Rodríguez-Perales, S. and Wirbel, J. and Maistrenko, O.M. and Akanni, W.A. and Alashkar Alhamwe, B. and Alves, R.J. and Carrato, A. and Erasmus, H.P. and Estudillo, L. and Finkelmeier, F. and Fullam, A. and Glazek, A.M. and Gómez-Rubio, P. and Hercog, R. and Jung, F. and Kandels, S. and Kersting, S. and Langheinrich, M. and Márquez, M. and Molero, X. and Orakov, A. and Van Rossum, T. and Torres-Ruiz, R. and Telzerow, A. and Zych, K. and Benes, V. and Zeller, G. and Trebicka, J. and Real, F.X. and Malats, N. and Bork, P.
Gut 71 (7): 1359-1372. 7 June 2022

Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath, J. and Du, W. and Pruene, A. and Braun, T. and Thommandru, B. and Turk, R. and Sturgeon, M.L. and Kurgan, G.L. and Amini, L. and Stein, M. and Zittel, T. and Martini, S. and Ostendorf, L. and Wilhelm, A. and Akyüz, L. and Rehm, A. and Hoepken, U.E. and Pruß, A. and Künkele, A. and Jacobi, A.M. and Volk, H.D. and Schmueck-Henneresse, M. and Stripecke, R. and Reinke, P. and Wagner, D.L.
Molecular Therapy - Methods and Clinical Development 25 : 311-330. 9 June 2022

Modular deep neural networks for automatic quality control of retinal optical coherence tomography scans.
Kauer-Bonin, J. and Yadav, S.K. and Beckers, I. and Gawlik, K. and Motamedi, S. and Zimmermann, H.G. and Kadas, E.M. and Haußer, F. and Paul, F. and Brandt, A.U.
Computers in Biology and Medicine 141 : 104822. 1 February 2022

Identification of early neurodegenerative pathways in progressive multiple sclerosis.
Kaufmann, M. and Schaupp, A.L. and Sun, R. and Coscia, F. and Dendrou, C.A. and Cortes, A. and Kaur, G. and Evans, H.G. and Mollbrink, A. and Navarro, J.F. and Sonner, J.K. and Mayer, C. and DeLuca, G.C. and Lundeberg, J. and Matthews, P.M. and Attfield, K.E. and Friese, M.A. and Mann, M. and Fugger, L.
Nature Neuroscience 25 (7): 944-955. July 2022

MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.
Kaufmann, T.L. and Petkovic, M. and Watkins, T.B.K. and Colliver, E.C. and Laskina, S. and Thapa, N. and Minussi, D.C. and Navin, N. and Swanton, C. and Van Loo, P. and Haase, K. and Tarabichi, M. and Schwarz, R.F.
Genome Biology 23 (1): 241. 14 November 2022

Real-time measurements of intracellular cAMP gradients using FRET-based cAMP nanorulers.
Kayser, C. and Lohse, M.J. and Bock, A.
Methods in Molecular Biology 2483 : 1-13. 2022

Nonproductive exposure of PBMCs to SARS‐CoV ‐2 induces cell‐intrinsic innate immune responses.
Kazmierski, J. and Friedmann, K. and Postmus, D. and Emanuel, J. and Fischer, C. and Jansen, J. and Richter, A. and Bosquillon de Jarcy, L. and Schüler, C. and Sohn, M. and Sauer, S. and Drosten, C. and Saliba, A.E. and Sander, L.E. and Müller, M.A. and Niemeyer, D. and Goffinet, C.
Molecular Systems Biology 18 (8): e10961. 1 August 2022

A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity.
Kedor, C. and Freitag, H. and Meyer-Arndt, L. and Wittke, K. and Hanitsch, L.G. and Zoller, T. and Steinbeis, F. and Haffke, M. and Rudolf, G. and Heidecker, B. and Bobbert, T. and Spranger, J. and Volk, H.D. and Skurk, C. and Konietschke, F. and Paul, F. and Behrends, U. and Bellmann-Strobl, J. and Scheibenbogen, C.
Nature Communications 13 (1): 5104. 30 August 2022

Placental transcriptome profiling in subtypes of diabetic pregnancies is strongly confounded by fetal sex.
Kedziora, S.M. and Obermayer, B. and Sugulle, M. and Herse, F. and Kräker, K. and Haase, N. and Langmia, I.M. and Müller, D.N. and Staff, A.C. and Beule, D. and Dechend, R.
International Journal of Molecular Sciences 23 (23): 15388. 6 December 2022

Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Keil, P. and Wulf, A. and Kachariya, N. and Reuscher, S. and Hühn, K. and Silbern, I. and Altmüller, J. and Keller, M. and Stehle, R. and Zarnack, K. and Sattler, M. and Urlaub, H. and Sträßer, K.
Nucleic Acids Research : gkac1206. 30 December 2022

Normative data and conversion equation for spectral-domain optical coherence tomography in an international healthy control cohort.
Kenney, R. and Liu, M. and Hasanaj, L. and Joseph, B. and Al-Hassan, A.A. and Balk, L. and Behbehani, R. and Brandt, A.U. and Calabresi, P.A. and Frohman, E.M. and Frohman, T. and Havla, J. and Hemmer, B. and Jiang, H. and Knier, B. and Korn, T. and Leocani, L. and Martínez-Lapiscina, E.H. and Papadopoulou, A. and Paul, F. and Petzold, A. and Pisa, M. and Villoslada, P. and Zimmermann, H. and Ishikawa, H. and Schuman, J.S. and Wollstein, G. and Chen, Y. and Saidha, S. and Thorpe, L.E. and Galetta, S.L. and Balcer, L.J.
Journal of Neuro-Ophthalmology 42 (4): 442-453. December 2022

The role of optical coherence tomography criteria and machine learning in multiple sclerosis and optic neuritis diagnosis.
Kenney, R.C. and Liu, M. and Hasanaj, L. and Joseph, B. and Al-Hassan, A.A. and Balk, L.J. and Behbehani, R. and Brandt, A. and Calabresi, P.A. and Frohman, E. and Frohman, T.C. and Havla, J. and Hemmer, B. and Jiang, H. and Knier, B. and Korn, T. and Leocani, L. and Martinez-Lapiscina, E.H. and Papadopoulou, A. and Paul, F. and Petzold, A. and Pisa, M. and Villoslada, P. and Zimmermann, H. and Thorpe, L.E. and Ishikawa, H. and Schuman, J.S. and Wollstein, G. and Chen, Y. and Saidha, S. and Galetta, S. and Balcer, L.J.
Neurology 99 (11): e1100-e1112. 13 September 2022

Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes.
Khedkar, S. and Smyshlyaev, G. and Letunic, I. and Maistrenko, O.M. and Coelho, L.P. and Orakov, A. and Forslund, S.K. and Hildebrand, F. and Luetge, M. and Schmidt, T.S.B. and Barabas, O. and Bork, P.
Nucleic Acids Research 50 (6): 3155-3168. 8 April 2022

SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta.
Kirchenwitz, M. and Stahnke, S. and Prettin, S. and Borowiak, M. and Menke, L. and Sieben, C. and Birchmeier, C. and Rottner, K. and Stradal, T.E.B. and Steffen, A.
Cells 11 (10): 1648. 16 May 2022

Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve.
Kleineidam, L. and Wolfsgruber, S. and Weyrauch, A.S. and Zulka, L.E. and Forstmeier, S. and Roeske, S. and van den Bussche, H. and Kaduszkiewicz, H. and Wiese, B. and Weyerer, S. and Werle, J. and Fuchs, A. and Pentzek, M. and Brettschneider, C. and König, H.H. and Weeg, D. and Bickel, H. and Luppa, M. and Rodriguez, F.S. and Freiesleben, S.D. and Erdogan, S. and Unterfeld, C. and Peters, O. and Spruth, E.J. and Altenstein, S. and Lohse, A. and Priller, J. and Fliessbach, K. and Kobeleva, X. and Schneider, A. and Bartels, C. and Schott, B.H. and Wiltfang, J. and Maier, F. and Glanz, W. and Incesoy, E.I. and Butryn, M. and Düzel, E. and Buerger, K. and Janowitz, D. and Ewers, M. and Rauchmann, B.S. and Perneczky, R. and Kilimann, I. and Görß, D. and Teipel, S. and Laske, C. and Munk, M.H.J. and Spottke, A. and Roy, N. and Brosseron, F. and Heneka, M.T. and Ramirez, A. and Yakupov, R. and Scherer, M. and Maier, W. and Jessen, F. and Riedel-Heller, S.G. and Wagner, M.
Frontiers in Psychology 13 : 957308. 8 December 2022

Proteolytic cleavage of the extracellular domain affects signaling of parathyroid hormone 1 receptor.
Klenk, C. and Hommers, L. and Lohse, M.J.
Frontiers in Endocrinology 13 : 839351. 22 February 2022

Urinary single-cell sequencing captures kidney injury and repair processes in human acute kidney injury.
Klocke, J. and Kim, S.J. and Skopnik, C.M. and Hinze, C. and Boltengagen, A. and Metzke, D. and Grothgar, E. and Prskalo, L. and Wagner, L. and Freund, P. and Görlich, N. and Muench, F. and Schmidt-Ott, K.M. and Mashreghi, M.F. and Kocks, C. and Eckardt, K.U. and Rajewsky, N. and Enghard, P.
Kidney International 102 (6): 1359-1370. December 2022

Meconium microbiome of very preterm infants across Germany.
Klopp, J. and Ferretti, P. and Meyer, C.U. and Hilbert, K. and Haiß, A. and Marißen, J. and Henneke, P. and Hudalla, H. and Pirr, S. and Viemann, D. and Zemlin, M. and Forslund, S.K. and Härtel, C. and Bork, P. and Gehring, S. and Van Rossum, T.
mSphere 7 (1): e0080821. 23 February 2022

Antibiotic resistance genes in river biofilms: a metagenomic approach toward the identification of sources and candidate hosts.
Kneis, D. and Berendonk, T.U. and Forslund, S.K. and Hess, S.
Environmental Science and Technology 56 (21): 14913-14922. 1 November 2022

A brief introduction to current cancer gene therapy.
Kobelt, D. and Pahle, J. and Walther, W.
Methods in Molecular Biology 2521 (3): 1-21. 23 June 2022

Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.
Kofla, G. and Radecke, C. and Frentsch, M. and Walther, W. and Stintzing, S. and Riess, H. and Bullinger, L. and Na, I.K.
OncoImmunology 11 (1): 2068109. 25 April 2022

Association of ultra-rare coding variants with genetic generalized epilepsy: a case-control whole exome sequencing study.
Koko, M. and Motelow, J.E. and Stanley, K.E. and Bobbili, D.R. and Dhindsa, R.S. and May, P.
Epilepsia 63 (3): 723-735. March 2022

Functional indications for transposase domestications - characterization of the human piggyBac transposase derived (PGBD) activities.
Kolacsek, O. and Wachtl, G. and Fóthi, Á. and Schamberger, A. and Sándor, S. and Pergel, E. and Varga, N. and Raskó, T. and Izsvák, Z. and Apáti, Á. and Orbán, T.I.
Gene 834 : 146609. 5 August 2022

Regional gene expression patterns are associated with task-specific brain activation during reward and emotion processing measured with functional MRI.
Komorowski, A. and Murgaš, M. and Vidal, R. and Singh, A. and Gryglewski, G. and Kasper, S. and Wiltfang, J. and Lanzenberger, R. and Goya-Maldonado, R.
Human Brain Mapping 43 (17): 5266-5280. 1 December 2022

Identification of novel genes whose expression in adipose tissue affects body fat mass and distribution: an RNA-Seq and Mendelian Randomization study.
Konigorski, S. and Janke, J. and Patone, G. and Bergmann, M.M. and Lippert, C. and Hübner, N. and Kaaks, R. and Boeing, H. and Pischon, T.
European Journal of Human Genetics 11 August 2022 (In Press)

Simultaneous dimensionality reduction and integration for single-cell ATAC-seq data using deep learning.
Kopp, W. and Akalin, A. and Ohler, U.
Nature Machine Intelligence 4 (2): 162-168. February 2022

EASIX and severe endothelial complications after CD19-directed CAR-T Cell therapy-a cohort study.
Korell, F. and Penack, O. and Mattie, M. and Schreck, N. and Benner, A. and Krzykalla, J. and Wang, Z. and Schmitt, M. and Bullinger, L. and Müller-Tidow, C. and Dreger, P. and Luft, T.
Frontiers in Immunology 13 : 877477. 8 April 2022

Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis.
Kortüm, B. and Radhakrishnan, H. and Zincke, F. and Sachse, C. and Burock, S. and Keilholz, U. and Dahlmann, M. and Walther, W. and Dittmar, G. and Kobelt, D. and Stein, U.
Oncogene 41 (39): 4446-4458. 23 September 2022

Deletion in the Y chromosome of B10.BR-Y(del) mice alters transcription from MSYq genes and has moderate effect on DNA methylation.
Kotarska, K. and Doniec, A. and Korostyński, M. and Piechota, M. and Gołas, A. and Lisowski, P. and Styrna, J.
Reproductive Biology 22 (2): 100614. June 2022

15-keto-Prostaglandin E(2) exhibits bioactive role by modulating glomerular cytoarchitecture through EP2/EP4 receptors.
Kourpa, A. and Kaiser-Graf, D. and Sporbert, A. and Philippe, A. and Catar, R. and Rothe, M. and Mangelsen, E. and Schulz, A. and Bolbrinker, J. and Kreutz, R. and Panáková, D.
Life Sciences 310 : 121114. 1 December 2022

Computational approaches to predicting treatment response to obesity using neuroimaging.
Kozarzewski, L. and Maurer, L. and Mähler, A. and Spranger, J. and Weygandt, M.
Reviews in Endocrine & Metabolic Disorders 23 (4): 773–805. August 2022

Reduced splenic uptake on (68)Ga-Pentixafor-PET/CT imaging in multiple myeloma - a potential imaging biomarker for disease prognosis.
Kraus, S. and Klassen, P. and Kircher, M. and Dierks, A. and Habringer, S. and Gäble, A. and Kortüm, K.M. and Weinhold, N. and Ademaj-Kospiri, V. and Werner, R.A. and Schirbel, A. and Buck, A.K. and Herhaus, P. and Wester, H.J. and Rosenwald, A. and Weber, W.A. and Einsele, H. and Keller, U. and Rasche, L. and Lapa, C.
Theranostics 12 (13): 5986-5994. 8 August 2022

A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse.
Krause, F. and Mohebian, K. and Delpero, M. and Hesse, D. and Kuehn, R. and Arends, D. and Brockmann, G.A.
Mammalian Genome 33 (3): 465–470. September 2022

Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society.
Kroke, A. and Schmidt, A. and Amini, A.M. and Kalotai, N. and Lehmann, A. and Haardt, J. and Bauer, J.M. and Bischoff-Ferrari, H.A. and Boeing, H. and Egert, S. and Ellinger, S. and Kühn, T. and Louis, S. and Lorkowski, S. and Nimptsch, K. and Remer, T. and Schulze, M.B. and Siener, R. and Stangl, G.I. and Volkert, D. and Zittermann, A. and Buyken, A.E. and Watzl, B. and Schwingshackl, L.
European Journal of Nutrition 61 (4): 2091-2101. June 2022

Overnight unilateral withdrawal of thalamic deep brain stimulation to identify reversibility of gait disturbances.
Kroneberg, D. and Al-Fatly, B. and Schmitz-Hübsch, T. and Gandor, F. and Gruber, D. and Ebersbach, G. and Horn, A. and Kühn, A.A.
Experimental Neurology 355 : 114135. September 2022

GMP-grade manufacturing and quality control of a non-virally engineered advanced therapy medicinal product for personalized treatment of age-related macular degeneration.
Kropp, M. and Harmening, N. and Bascuas, T. and Johnen, S. and De Clerck, E. and Fernández, V. and Ronchetti, M. and Cadossi, R. and Zanini, C. and Scherman, D. and Ivics, Z. and Marie, C. and Izsvák, Z. and Thumann, G.
Biomedicines 10 (11): 2777. November 2022

Paracrine interleukin 6 induces cerebral remodeling at early stages after unilateral common carotid artery occlusion in mice.
Kuffner, M.T.C. and Koch, S.P and Kirchner, M. and Mueller, S. and Lips, J. and An, J. and Mertins, P. and Dirnagl, U. and Endres, M. and Boehm-Sturm, P. and Harms, C. and Hoffmann, C.J.
Frontiers in Cardiovascular Medicine 8 : 805095. 27 January 2022

Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses.
Kunath, B.J. and Hickl, O. and Queirós, P. and Martin-Gallausiaux, C. and Lebrun, L.A. and Halder, R. and Laczny, C.C. and Schmidt, T.S.B. and Hayward, M.R. and Becher, D. and Heintz-Buschart, A. and de Beaufort, C. and Bork, P. and May, P. and Wilmes, P.
Microbiome 10 (1): 243. 28 December 2022

Small cell lung cancer stem cells display mesenchymal properties and exploit immune checkpoint pathways in activated cytotoxic T lymphocytes.
Kursunel, M.A. and Taskiran, E.Z. and Tavukcuoglu, E. and Yanik, H. and Demirag, F. and Karaosmanoglu, B. and Ozbay, F.G. and Uner, A. and Esendagli, D. and Kizilgoz, D. and Yilmaz, U. and Esendagli, G.
Cancer Immunology Immunotherapy 71 (2): 445-459. February 2022

Statistical analysis in the German National Cohort (NAKO) - specific aspects and general recommendations.
Kuss, O. and Becher, H. and Wienke, A. and Ittermann, T. and Ostrzinski, S. and Schipf, S. and Schmidt, C.O. and Leitzmann, M. and Pischon, T. and Krist, L. and Roll, S. and Sand, M. and Pohlabeln, H. and Rach, S. and Jöckel, K.H. and Stang, A. and Mueller, U.A. and Werdecker, A. and Westerman, R. and Greiser, K.H. and Michels, K.B.
European Journal of Epidemiology 37 (4): 429-436. April 2022

Genome engineering in rodents - status quo and perspectives.
Kühn, R.
Laboratory Animals 56 (1): 83-87. 1 February 2022

Magnetic field-induced interactions between phones containing magnets and cardiovascular implantable electronic devices: Flip it to be safe?
Lacour, P. and Dang, P.L. and Heinzel, F.R. and Parwani, A.S. and Bähr, F. and Kucher, A. and Hohendanner, F. and Niendorf, T. and Rahimi, F. and Saha, N. and Han, H. and Rubarth, K. and Sherif, M. and Boldt, L.H. and Pieske, B. and Blaschke, F.
Heart Rhythm 19 (3): 372-380. March 2022

Interleukin 8 in postoperative delirium - preliminary findings from two studies.
Lammers-Lietz, F. and Akyuz, L. and Feinkohl, I. and Lachmann, C. and Pischon, T. and Volk, H.D. and von Häfen, C. and Yürek, F. and Winterer, G. and Spies, C.D.
Brain Behavior & Immunity - Health 20 : 100419. March 2022

Rapid single-cell identification of Epstein-Barr virus-specific T-cell receptors for cellular therapy.
Lammoglia Cobo, M.F. and Welters, C. and Rosenberger, L. and Leisegang, M. and Dietze, K. and Pircher, C. and Penter, L. and Gary, R. and Bullinger, L. and Takvorian, A. and Moosmann, A. and Dornmair, K. and Blankenstein, T. and Kammertöns, T. and Gerbitz, A. and Hansmann, L.
Cytotherapy 24 (8): 818-826. August 2022

The evolutionary dynamics of extrachromosomal DNA in human cancers.
Lange, J.T. and Rose, J.C. and Chen, C.Y. and Pichugin, Y. and Xie, L. and Tang, J. and Hung, K.L. and Yost, K.E. and Shi, Q. and Erb, M.L. and Rajkumar, U. and Wu, S. and Taschner-Mandl, S. and Bernkopf, M. and Swanton, C. and Liu, Z. and Huang, W. and Chang, H.Y. and Bafna, V. and Henssen, A.G. and Werner, B. and Mischel, P.S.
Nature Genetics 54 (10): 1527-1533. October 2022

A flexible tool to correct superimposed mass isotopologue distributions in GC-APCI-MS flux experiments.
Langenhan, J. and Jaeger, C. and Baum, K. and Simon, M. and Lisec, J.
Metabolites 12 (5): 408. 29 April 2022

Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling.
Langer, H.T. and West, D. and Senden, J. and Spuler, S. and van Loon, L.J.C. and Baar, K.
Scientific Reports 12 (1): 7553. 9 May 2022

Sox9 is required for nail bed differentiation and digit tip regeneration.
Lao, M. and Hurtado, A. and de Castro, A.C. and Burgos, M. and Jiménez, R. and Barrionuevo, F.J.
Journal of Investigative Dermatology 142 (10): 2613-2622. October 2022

Efficient CRISPR/Cas9-mediated mutagenesis in primary human B cells for identifying plasma cell regulators.
Le, T.A. and Chu, V.T. and Lino, A.C. and Schrezenmeier, E. and Kressler, C. and Hamo, D. and Rajewsky, K. and Dörner, T. and Dang, V.D.
Molecular Therapy - Nucleic Acids 30 : 621-632. 13 December 2022

Different classes of genomic inserts contribute to human antibody diversity.
Lebedin, M. and Foglierini, M. and Khorkova, S. and Vázquez García, C. and Ratswohl, C. and Davydov, A.N. and Turchaninova, M.A. and Daubenberger, C. and Chudakov, D.M. and Lanzavecchia, A. and de la Rosa, K.
Proceedings of the National Academy of Sciences of the United States of America 119 (36): e2205470119. 6 September 2022

Heteroplasmy of wild type mitochondrial DNA variants in mice causes metabolic heart disease with pulmonary hypertension and frailty.
Lechuga-Vieco, A.V. and Latorre-Pellicer, A. and Calvo, E. and Torroja, C. and Pellico, J. and Acín-Pérez, R. and García-Gil, M.L. and Santos, A. and Bagwan, N. and Bonzon-Kulichenko, E. and Magni, R. and Benito, M. and Justo-Méndez, R. and Simon, A.K. and Sánchez-Cabo, F. and Vázquez, J. and Ruíz-Cabello, J. and Enríquez, J.A.
Circulation 145 (12): 1084-1101. 5 April 2022

Mafa-dependent GABAergic activity promotes mouse neonatal apneas.
Lecoin, L. and Dempsey, B. and Garancher, A. and Bourane, S. and Ruffault, P.L. and Morin-Surun, M.P. and Rocques, N. and Goulding, M. and Eychène, A. and Pouponnot, C. and Fortin, G. and Champagnat, J.
Nature Communications 13 (1): 3284. 7 June 2022

B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice.
Lee, M.S.J. and Inoue, T. and Ise, W. and Matsuo-Dapaah, J. and Wing, J.B. and Temizoz, B. and Kobiyama, K. and Hayashi, T. and Patil, A. and Sakaguchi, S. and Simon, A.K. and Bezbradica, J.S. and Nagatoishi, S. and Tsumoto, K. and Inoue, J.I. and Akira, S. and Kurosaki, T. and Ishii, K.J. and Coban, C.
Journal of Experimental Medicine 219 (2): e20211336. 7 February 2022

Alport syndrome and autosomal dominant tubulointerstitial kidney disease frequently underlie end stage renal disease of unknown origin - a single center analysis.
Leenen, E. and Erger, F. and Altmüller, J. and Wenzel, A. and Thiele, H. and Harth, A. and Tschernoster, N. and Lokhande, S. and Joerres, A. and Becker, J.U. and Ekici, A. and Huettel, B. and Beck, B. and Weidemann, A.
Nephrology Dialysis Transplantation 37 (10): 1895-1905. 22 September 2022

Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng, H. and Zhang, H. and Li, L. and Zhang, S. and Wang, Y. and Chavda, S.J. and Galas-Filipowicz, D. and Lou, H. and Ersek, A. and Morris, E.V. and Sezgin, E. and Lee, Y.H. and Li, Y. and Lechuga-Vieco, A.V. and Tian, M. and Mi, J.Q. and Yong, K. and Zhong, Q. and Edwards, C.M. and Simon, A.K. and Horwood, N.J.
Nature Communications 13 (1): 7868. 22 December 2022

A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies.
Lessel, D. and Rading, K. and Campbell, S.E. and Thiele, H. and Altmüller, J. and Gordon, L.B. and Kubisch, C.
American Journal of Medical Genetics A 188 (1): 216-223. January 2022

Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M. and Wang, Y.H. and Kaufmann, U. and Gerbeth, L. and Sand, A. and Brunkhorst, M. and Weidner, P. and Ziegler, J.F. and Böttcher, C. and Schlickeiser, S. and Fernández, C. and Yamashita, M. and Stauderman, K. and Sun, K. and Kunkel, D. and Prakriya, M. and Sanders, A.D. and Siegmund, B. and Feske, S. and Weidinger, C.
EMBO Molecular Medicine : e15687. 2 August 2022

Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors.
Li, C. and Wang, H. and Gil, S. and Germond, A. and Fountain, C. and Baldessari, A. and Kim, J. and Liu, Z. and Georgakopoulou, A. and Radtke, S. and Raskó, T. and Pande, A. and Chiang, C. and Chin, E. and Yannaki, E. and Izsvak, Z. and Papayannopoulou, T. and Kiem, H.P. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 24 : 127-141. 10 March 2022

Fly Cell Atlas: a single-nucleus transcriptomic atlas of the adult fruit fly.
Li, H. and Janssens, J. and De Waegeneer, M. and Kolluru, S.S. and Davie, K. and Gardeux, V. and Saelens, W. and David, F.P.A. and Brbić, M. and Spanier, K. and Leskovec, J. and McLaughlin, C.N. and Xie, Q. and Jones, R.C. and Brueckner, K. and Shim, J. and Tattikota, S.G. and Schnorrer, F. and Rust, K. and Nystul, T.G. and Carvalho-Santos, Zi. and Ribeiro, C. and Pal, S. and Mahadevaraju, S. and Przytycka, T.M. and Allen, A.M. and Goodwin, S.F. and Berry, C.W. and Fuller, M.T. and White-Cooper, H. and Matunis, E.L. and DiNardo, S. and Galenza, A. and O'Brien, L.E. and Dow, J.A.T. and Jasper, H. and Oliver, B. and Perrimon, N. and Deplancke, B. and Quake, S.R. and Luo, L. and Aerts, S.
Science 375 (6584): eabk2432. 4 March 2022

Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D. and Oshima, M. and Stange, D.E. and Sigal, M.
Gastroenterology 162 (4): 1067-1087. April 2022

High-content analysis of neuronal morphology in human iPSC-derived neurons.
Lickfett, S. and Menacho, C. and Zink, A. and Telugu, N.S. and Beller, M. and Diecke, S. and Cambridge, S. and Prigione, A.
STAR Protocols 3 (3): 101567. 16 September 2022

Mako: a graph-based pattern growth approach to detect complex structural variants.
Lin, J. and Yang, X. and Kosters, W. and Xu, T. and Jia, Y. and Wang, S. and Zhu, Q. and Ryan, M. and Guo, L. and Zhang, C. and Lee, C. and Devine, S.E. and Eichler, E.E. and Ye, K.
Genomics, Proteomics and Bioinformatics 20 (1): 205-218. February 2022

Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function.
Lin, S.J. and Vona, B. and Porter, H.M. and Izadi, M. and Huang, K. and Lacassie, Y. and Rosenfeld, J.A. and Khan, S. and Petree, C. and Ali, T.A. and Muhammad, N. and Khan, S.A. and Muhammad, N. and Liu, P. and Haymon, M.L. and Rüschendorf, F. and Kong, I.K. and Schnapp, L. and Shur, N. and Chorich, L. and Layman, L. and Haaf, T. and Pourkarimi, E. and Kim, H.G. and Varshney, G.K.
Human Mutation 43 (10): 1472-1489. October 2022

Serum glial fibrillary acidic protein correlates with retinal structural damage in aquaporin-4 antibody positive neuromyelitis optica spectrum disorder.
Lin, T.Y. and Schindler, P. and Grittner, U. and Oertel, F.C. and Lu, A. and Motamedi, S. and Yadav, S.K. and Duchow, A.S. and Jarius, S. and Kuhle, J. and Benkert, P. and Brandt, A.U. and Bellmann-Strobl, J. and Schmitz-Hübsch, T. and Paul, F. and Ruprecht, K. and Zimmermann, H.G.
Multiple Sclerosis and Related Disorders 67 : 104100. November 2022

HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin, Y.H. and Major, J.L. and Liebner, T. and Hourani, Z. and Travers, J.G. and Wennersten, S.A. and Haefner, K.R. and Cavasin, M.A. and Wilson, C.E. and Jeong, M.Y. and Han, Y. and Gotthardt, M. and Ferguson, S.K. and Ambardekar, A.V. and Lam, M.P. and Choudhary, C. and Granzier, H.L. and Woulfe, K.C. and McKinsey, T.A.
Journal of Clinical Investigation 132 (10): e148333. 16 May 2022

Diffusion-weighted magnetic resonance imaging in rat kidney using two-dimensional navigated, interleaved echo-planar imaging at 7.0 T.
Liu, Q. and Xu, Z. and Zhao, K. and Hoge, W.S. and Zhang, X. and Mei, Y. and Lu, Q. and Niendorf, T. and Feng, Y.
NMR in Biomedicine 35 (5): e4652. May 2022

Hemodialysis and biotransformation of erythrocyte epoxy fatty acids in peripheral tissue.
Liu, T. and Dogan, I. and Rothe, M. and Kunz, J.V. and Knauf, F. and Gollasch, M. and Luft, F.C. and Gollasch, B.
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Hemodialysis and plasma oxylipin biotransformation in peripheral tissue.
Liu, T. and Dogan, I. and Rothe, M. and Kunz, J.V. and Knauf, F. and Gollasch, M. and Luft, F.C. and Gollasch, B.
Metabolites 12 (1): 34. 4 January 2022

Bioaccumulation of blood long-chain fatty acids during hemodialysis.
Liu, T. and Dogan, I. and Rothe, M. and Reichardt, J. and Knauf, F. and Gollasch, M. and Luft, F.C. and Gollasch, B.
Metabolites 12 (3): 269. 21 March 2022

Structural basis of phosphatidylinositol 3-kinase C2α function.
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Nature Structural & Molecular Biology 29 (3): 218-228. March 2022

Targeted analysis of cell-free circulating tumor DNA is suitable for early relapse and actionable target detection in patients with neuroblastoma.
Lodrini, M. and Graef, J. and Thole-Kliesch, T.M. and Astrahantseff, K. and Sprüssel, A. and Grimaldi, M. and Peitz, C. and Linke, R.B. and Hollander, J.F. and Lankes, E. and Künkele, A. and Oevermann, L. and Schwabe, G. and Fuchs, J. and Szymansky, A. and Schulte, J.H. and Hundsdoerfer, P. and Eckert, C. and Amthauer, H. and Eggert, A. and Deubzer, H.E.
Clinical Cancer Research 28 (9): 1809-1820. 1 May 2022

Circulating cell-free DNA assessment in biofluids from children with neuroblastoma demonstrates feasibility and potential for minimally invasive molecular diagnostics.
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Cancers 14 (9): 2080. 21 April 2022

Fibrin-targeting molecular MRI in inflammatory CNS disorders.
Lohmeier, J. and Silva, R.V. and Tietze, A. and Taupitz, M. and Kaneko, T. and Prüss, H. and Paul, F. and Infante-Duarte, C. and Hamm, B. and Caravan, P. and Makowski, M.R.
European Journal of Nuclear Medicine and Molecular Imaging 49 (11): 3692–3704. September 2022

Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.
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Stem Cell Research 61 : 102742. May 2022

Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders.
Lu, A. and Zimmermann, H.G. and Specovius, S. and Motamedi, S. and Chien, C. and Bereuter, C. and Lana-Peixoto, M.A. and Fontenelle, M.A. and Ashtari, F. and Kafieh, R. and Dehghani, A. and Pourazizi, M. and Pandit, L. and D'Cunha, A. and Kim, H.J. and Hyun, J.W. and Jung, S.K. and Leocani, L. and Pisa, M. and Radaelli, M. and Siritho, S. and May, E.F. and Tongco, C. and De Sèze, J. and Senger, T. and Palace, J. and Roca-Fernández, A. and Leite, M.I. and Sharma, S.M. and Stiebel-Kalish, H. and Asgari, N. and Soelberg, K.K. and Martinez-Lapiscina, E.H. and Havla, J. and Mao-Draayer, Y. and Rimler, Z. and Reid, A. and Marignier, R. and Cobo-Calvo, A. and Altintas, A. and Tanriverdi, U. and Yildirim, R. and Aktas, O. and Ringelstein, M. and Albrecht, P. and Tavares, I.M. and Bichuetti, D.B. and Jacob, A. and Huda, S. and Soto de Castillo, I. and Petzold, A. and Green, A.J. and Yeaman, M.R. and Smith, T.J. and Cook, L. and Paul, F. and Brandt, A.U. and Oertel, F.C.
Journal of Neurology Neurosurgery and Psychiatry 93 (2): 188-195. February 2022

Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig, L.S. and Lareau, C.A. and Bao, E.L. and Liu, N. and Utsugisawa, T. and Tseng, A.M. and Myers, S.A. and Verboon, J.M. and Ulirsch, J.C. and Luo, W. and Muus, C. and Fiorini, C. and Olive, M.E. and Vockley, C.M. and Munschauer, M. and Hunter, A. and Ogura, H. and Yamamoto, T. and Inada, H. and Nakagawa, S. and Ozono, S. and Subramanian, V. and Chiarle, R. and Glader, B. and Carr, S.A. and Aryee, M.J. and Kundaje, A. and Orkin, S. and Regev, A. and McCavit, T. and Kanno, H. and Sankaran, V.G.
Blood 139 (16): 2534-2546. 21 April 2022

AntiSplodge: a neural-network-based RNA-profile deconvolution pipeline designed for spatial transcriptomics.
Lund, J.B. and Lindberg, E.L. and Maatz, H. and Pottbaecker, F. and Hübner, N. and Lippert, C.
NAR Genomics and Bioinformatics 4 (4): lqac073. December 2022

LRFN5 locus structure is associated with autism and influenced by the sex of the individual and locus conversions.
Lybaek, H. and Robson, M. and de Leeuw, N. and Hehir-Kwa, J.Y. and Jeffries, A. and Haukanes, B.I. and Berland, S. and de Bruijn, D. and Mundlos, S. and Spielmann, M. and Houge, G.
Autism research 15 (3): 421-433. 16 March 2022

Tongue immune compartment analysis reveals spatial macrophage heterogeneity.
Lyras, E.M. and Zimmermann, K. and Wagner, L.K. and Dörr, D. and Klose, C.S.N and Fischer, C. and Jung, S. and Yona, S. and Hovav, A.H. and Stenzel, W. and Dommerich, S. and Conrad, T. and Leutz, A. and Mildner, A.
eLife 11 : 77490. 24 June 2022

Renal deletion of LRRC8/VRAC channels induces proximal tubulopathy.
López-Cayuqueo, K.I. and Planells-Cases, R. and Pietzke, M. and Oliveras, A. and Kempa, S. and Bachmann, S. and Jentsch, T.J.
Journal of the American Society of Nephrology 33 (8): 1528-1545. August 2022

Impact of metabolic stress induced by diets, aging and fasting on tissue oxygen consumption.
Mackert, O. and Wirth, E.K. and Sun, R. and Winkler, J. and Liu, A. and Renko, K. and Kunz, S. and Spranger, J. and Brachs, S.
Molecular Metabolism 64 : 101563. October 2022

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
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Nature Genetics 54 (5): 560-572. May 2022

SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.
Maharana, S. and Kretschmer, S. and Hunger, S. and Yan, X. and Kuster, D. and Traikov, S. and Zillinger, T. and Gentzel, M. and Elangovan, S. and Dasgupta, P. and Chappidi, N. and Lucas, N. and Maser, K.I. and Maatz, H. and Rapp, A. and Marchand, V. and Chang, Y.T. and Motorin, Y. and Hubner, N. and Hartmann, G. and Hyman, A.A. and Alberti, S. and Lee-Kirsch, M.A.
Molecular Cell 82 (19): 3712-3728.e10. 6 October 2022

Skin sodium accumulates in psoriasis and reflects disease severity.
Maifeld, A. and Wild, J. and Karlsen, T.V. and Rakova, N. and Wistorf, E. and Linz, P. and Jung, R. and Birukov, A. and Gimenez-Rivera, V.A. and Wilck, N. and Bartolomaeus, T. and Dechend, R. and Kleinewietfeld, M. and Forslund, S.K. and Krause, A. and Kokolakis, G. and Philipp, S. and Clausen, B.E. and Brand, A. and Waisman, A. and Kurschus, F.C. and Wegner, J. and Schultheis, M. and Luft, F.C. and Boschmann, M. and Kelm, M. and Wiig, H. and Kuehne, T. and Müller, D.N. and Karbach, S. and Markó, L.
Journal of Investigative Dermatology 142 (1): 166-178. January 2022

Loss of endothelial cytochrome P450 reductase induces vascular dysfunction in mice.
Malacarne, P.F. and Ratiu, C. and Gajos-Draus, A. and Müller, N. and Lopez, M. and Pflüger-Müller, B. and Ding, X. and Warwick, T. and Oo, J. and Siragusa, M. and Angioni, C. and Günther, S. and Weigert, A. and Geißlinger, G. and Lütjohann, D. and Schunck, W.H. and Fleming, I. and Brandes, R.P. and Rezende, F.
Hypertension 79 (6): 1216-1226. June 2022

Imaging and analysis of neuronal mitochondria in murine acute brain slices.
Malla, B. and Hauser, A. and Niesner, R. and Infante-Duarte, C.
Journal of Neuroscience Methods 372 : 109558. 15 April 2022

Teriflunomide preserves neuronal activity and protects mitochondria in brain slices exposed to oxidative stress.
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International Journal of Molecular Sciences 23 (3): 1538. 28 January 2022

Forebrain development - an intricate balance decides between health and disease.
Mamo, T.M. and Hammes, A.
Neuroforum 28 (4): 233-243. 25 November 2022

Satellite glia of the adult dorsal root ganglia harbor stem cells that yield glia under physiological conditions and neurons in response to injury.
Maniglier, M. and Vidal, M. and Bachelin, Corinne and Deboux, C. and Chazot, J. and Garcia-Diaz, B. and Baron-Van Evercooren, A.
Stem Cell Reports 17 (11): 2467-2483. 8 November 2022

The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation towards the kidney lineage.
Mansour, F. and Hinze, C. and Telugu, N.S. and Kresoja, J. and Shaheed, I.B. and Mosimann, C. and Diecke, S. and Schmidt-Ott, K.M.
eLife 11 : e80165. 12 October 2022

In vitro Kinase-to-Phosphosite database (iKiP-DB) predicts kinase activity in phosphoproteomic datasets.
Mari, T. and Mösbauer, K. and Wyler, E. and Landthaler, M. and Drosten, C. and Selbach, M.
Journal of Proteome Research 21 (6): 1575-1587. 3 June 2022

AQP4-IgG-seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.
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Multiple Sclerosis and Related Disorders 57 : 103356. January 2022

Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
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Journal of Biological Chemistry 298 (3): 101598. March 2022

Genomic variants reducing expression of two endocytic receptors in 46,XY differences of sex development.
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Human Mutation 43 (3): 420-433. March 2022

Towards reliable quantification of cell state velocities.
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PLoS Computational Biology 18 (9): e1010031. 28 September 2022

Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases.
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Molecular and functional characterization of BDNF-overexpressing human retinal pigment epithelial cells established by sleeping beauty transposon-mediated gene transfer.
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International Journal of Molecular Sciences 23 (21): 12982. 1 November 2022

The Cl(-)-channel TMEM16A is involved in the generation of cochlear Ca(2+) waves and promotes the refinement of auditory brainstem networks in mice.
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eLife 11 : e72251. 24 February 2022

ClearCNV: CNV calling from NGS panel data in the presence of ambiguity and noise.
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Cardio-respiratory motion-corrected 3D cardiac water-fat MRI using model-based image reconstruction.
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Assessing the relationship of patient reported outcome measures with functional status in dysferlinopathy: a Rasch analysis approach.
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Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
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Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis.
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Reliable assessment of telomere maintenance mechanisms in neuroblastoma.
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Parametric MRI detects aristolochic acid induced acute kidney injury.
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Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
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ChemMedChem 17 (19): e202200346. 6 October 2022

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
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Nature Communications 13 (1): 7641. 10 December 2022

Analyses of murine lymph node endothelial cell subsets using single-cell RNA sequencing and spectral flow cytometry.
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A high-resolution map of small-scale inversions in the gibbon genome.
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Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models.
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Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
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Biomedicines 10 (5): 1204. 23 May 2022

SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
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Prefrontal-amygdala emotion regulation and depression in multiple sclerosis.
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Brain Communications 4 (3): fcac152. 13 June 2022

Cutting edge: Serum but not mucosal antibody responses are associated with pre-existing SARS-CoV-2 spike cross-reactive CD4(+) T cells following BNT162b2 vaccination in the elderly.
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Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its host.
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Microbiome 10 (1): 229. 16 December 2022

Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
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Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations.
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Nature Biotechnology 40 (7): 1030-1034. 24 February 2022

Suicide nanoplasmids coding for ribosome-inactivating proteins.
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European Journal of Pharmaceutical Sciences 170 : 106107. 1 March 2022

Diet quality indices and gastrointestinal cancer risk: results from the Lifelines study.
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European Journal of Nutrition 61 : 317-327. February 2022

Ferritin trajectories over repeated whole blood donations: results from the FIND+ study.
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Hemodynamic stress-induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein.
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Journal of Cellular and Molecular Medicine 26 (16): 4440-4452. August 2022

Central macular topographic and volumetric measures: new biomarkers for detection of glaucoma.
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Targeting angiotensin type 2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice.
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In vitro and in vivo anti‐epileptic efficacy of eslicarbazepine acetate in a mouse model of KCNQ2‐related self‐limited epilepsy.
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British Journal of Pharmacology 179 (1): 84-102. January 2022

Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.
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Nature Communications 13 (1): 5332. 10 September 2022

Cardiac and pulmonary findings in dysferlinopathy: a 3-year, longitudinal study.
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Muscle & Nerve 65 (5): 531-540. May 2022

Genomic basis of syndromic short stature in an Algerian patient cohort.
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American Journal of Medical Genetics A 188 (2): 606-612. February 2022

Association of general and abdominal adiposity with postural changes in systolic blood pressure: results from the NAKO pretest and MetScan studies.
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Mechanical properties of murine hippocampal subregions investigated by atomic force microscopy and in vivo magnetic resonance elastography.
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Scientific Reports 12 (1): 16723. 6 October 2022

Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis.
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Immunity, inflammation and disease 10 (11): e728. November 2022

Prior optic neuritis detection on peripapillary ring scans using deep learning.
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Protocol and reference values for minimal detectable change of MyotonPRO and ultrasound imaging measurements of muscle and subcutaneous tissue.
Muckelt, P.E. and Warner, M.B. and Cheliotis-James, T. and Muckelt, R. and Hastermann, M. and Schoenrock, B. and Martin, D. and MacGregor, R. and Blottner, D. and Stokes, M.
Scientific Reports 12 (1): 13654. 11 August 2022

Characterization of critically ill patients with septic shock and sepsis-associated cardiomyopathy using cardiovascular MRI.
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ESC Heart Failure 9 (4): 2147-2156. August 2022

Early myocardial oedema can predict subsequent cardiomyopathy in high-dose anthracycline therapy.
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ESC Heart Failure 20 November 2022

Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus-specific.
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American Journal of Physiology Heart and Circulatory Physiology 322 (5): H785-H797. May 2022

DNA methyltransferases 3A and 3B target specific sequences during mouse gastrulation.
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Nature Structural & Molecular Biology 29 (12): 1252-1265. December 2022

Deep Visual Proteomics defines single-cell identity and heterogeneity.
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Nature Biotechnology 40 (8): 1231-1240. August 2022

Political knowledge and misinformation in the era of social media: evidence from the 2015 UK election.
Munger, K. and Egan, P.J. and Nagler, J. and Ronen, J. and Tucker, J.
British Journal of Political Science 52 (1): 107 - 127. January 2022

Increased salt intake decreases diet-induced thermogenesis in healthy volunteers: a randomized placebo-controlled study.
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Nutrients 14 (2): 253. 7 January 2022

Choroid plexus volume in multiple sclerosis vs neuromyelitis optica spectrum disorder: a retrospective, cross-sectional analysis.
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In vivo skin regeneration and wound healing using cell micro-transplantation.
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Pharmaceutics 14 (9): 1955. 15 September 2022

Vascular and liver homeostasis in juvenile mice require endothelial cyclic AMP-dependent protein kinase A.
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International Journal of Molecular Sciences 23 (19): 11419. 27 September 2022

USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer.
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Functional modulation of PTH1R activation and signaling by RAMP2.
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Mediterranean diet and atrial fibrillation: lessons learned from the AFHRI case-control study.
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Nutrients 14 (17): 3615. 1 September 2022

Candesartan does not activate PPAR(γ) and its target genes in early gestation trophoblasts.
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International Journal of Molecular Sciences 23 (20): 12326. October 2022

IL11 activates pancreatic stellate cells and causes pancreatic inflammation, fibrosis and atrophy in a mouse model of pancreatitis.
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International Journal of Molecular Sciences 23 (7): 3549. 24 March 2022

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
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Nature Communications 13 (1): 1009. 23 February 2022

Gene gun Her2/neu DNA vaccination: evaluation of vaccine efficacy in a syngeneic Her2/neu mouse tumor model.
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Methods in Molecular Biology 2521 (3): 129-154. 23 June 2022

Role of Gpnmb in atherosclerosis of female mice.
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Biochemical and Biophysical Research Communications 621 : 20-24. 17 September 2022

Best practice standards for circular RNA research.
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Nature Methods 19 (10): 1208-1220. October 2022

Pre-diagnostic C-reactive protein concentrations, CRP genetic variation and mortality among individuals with colorectal cancer in Western European populations.
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BMC Cancer 22 (1): 695. 24 June 2022

Upregulated complement receptors correlate with Fc gamma receptor 3A-positive natural killer and natural killer-T cells in neuromyelitis optica spectrum disorder.
Nishiyama, S. and Wright, A.E. and Lotan, I. and Mikami, T. and Paul, F. and Aoki, M. and Levy, M.
Journal of Neuroinflammation 19 (1): 296. 12 December 2022

Brain-wide interactions during hippocampal sharp wave ripples.
Nitzan, N. and Swanson, R. and Schmitz, D. and Buzsáki, G.
Proceedings of the National Academy of Sciences of the United States of America 119 (20): e2200931119. 17 May 2022

Clinical features and natural history of preadolescent nonsyndromic hypertrophic cardiomyopathy.
Norrish, G. and Cleary, A. and Field, E. and Cervi, E. and Boleti, O. and Ziółkowska, L. and Olivotto, I. and Khraiche, D. and Limongelli, G. and Anastasakis, A. and Weintraub, R. and Biagini, E. and Ragni, L. and Prendiville, T. and Duignan, S. and McLeod, K. and Ilina, M. and Fernandez, A. and Marrone, C. and Bökenkamp, R. and Baban, A. and Kubus, P. and Daubeney, P.E.F. and Sarquella-Brugada, G. and Cesar, S. and Klaassen, S. and Ojala, T.H. and Bhole, V. and Medrano, C. and Uzun, O. and Brown, E. and Gran, F. and Sinagra, G. and Castro, F.J. and Stuart, G. and Yamazawa, H. and Barriales-Villa, R. and Garcia-Guereta, L. and Adwani, S. and Linter, K. and Bharucha, T. and Gonzales-Lopez, E. and Siles, A. and Rasmussen, T.B. and Calcagnino, M. and Jones, C.B. and De Wilde, H. and Kubo, T. and Felice, T. and Popoiu, A. and Mogensen, J. and Mathur, S. and Centeno, F. and Reinhardt, Z. and Schouvey, S. and Elliott, P.M. and Kaski, J.P.
Journal of the American College of Cardiology 79 (20): 1986-1997. 24 May 2022

Relationship between maximal left ventricular wall thickness and sudden cardiac death in childhood onset hypertrophic cardiomyopathy.
Norrish, G. and Ding, T. and Field, E. and Cervi, E. and Ziółkowska, L. and Olivotto, I. and Khraiche, D. and Limongelli, G. and Anastasakis, A. and Weintraub, R. and Biagini, E. and Ragni, L. and Prendiville, T. and Duignan, S. and McLeod, K. and Ilina, M. and Fernandez, A. and Marrone, C. and Bökenkamp, R. and Baban, A. and Kubus, P. and Daubeney, P.E.F. and Sarquella-Brugada, G. and Cesar, S. and Klaassen, S. and Ojala, T.H. and Bhole, V. and Medrano, C. and Uzun, O. and Brown, E. and Gran, F. and Sinagra, G. and Castro, F.J. and Stuart, G. and Vignati, G. and Yamazawa, H. and Barriales-Villa, R. and Garcia-Guereta, L. and Adwani, S. and Linter, K. and Bharucha, T. and Garcia-Pavia, P. and Siles, A. and Rasmussen, T.B. and Calcagnino, M. and Jones, C.B. and De Wilde, H. and Kubo, T. and Felice, T. and Popoiu, A. and Mogensen, J. and Mathur, S. and Centeno, F. and Reinhardt, Z. and Schouvey, S. and O'Mahony, C. and Omar, R.Z. and Elliott, P.M. and Kaski, J.P.
Circulation Arrhythmia and Electrophysiology 15 (5): e010075. May 2022

External validation of the HCM Risk-Kids model for predicting sudden cardiac death in childhood hypertrophic cardiomyopathy.
Norrish, G. and Qu, C. and Field, E. and Cervi, E. and Khraiche, D. and Klaassen, S. and Ojala, T.H. and Sinagra, G. and Yamazawa, H. and Marrone, C. and Popoiu, A. and Centeno, F. and Schouvey, S. and Olivotto, I. and Day, S.M. and Colan, S. and Rossano, J. and Wittekind, S.G. and Saberi, S. and Russell, M. and Helms, A. and Ingles, J. and Semsarian, C. and Elliott, P.M. and Ho, C.Y. and Omar, R.Z. and Kaski, J.P.
European Journal of Preventive Cardiology 29 (4): 678-686. 30 March 2022

Generation of a NES-mScarlet red fluorescent reporter human iPSC line for live cell imaging and flow cytometric analysis and sorting using CRISPR-Cas9-mediated gene editing.
Nouri, P. and Zimmer, A. and Brüggemann, S. and Friedrich, R. and Kühn, R. and Prakash, N.
Cells 11 (2): 268. 13 January 2022

Familial long-read sequencing increases yield of de novo mutations.
Noyes, M.D. and Harvey, W.T. and Porubsky, D. and Sulovari, A. and Li, R. and Rose, N.R. and Audano, P.A. and Munson, K.M. and Lewis, A.P. and Hoekzema, K. and Mantere, T. and Graves-Lindsay, T.A. and Sanders, A.D. and Goodwin, S. and Kramer, M. and Mokrab, Y. and Zody, M.C. and Hoischen, A. and Korbel, J.O. and McCombie, W.R. and Eichler, E.E.
American Journal of Human Genetics 109 (4): 631-646. 7 April 2022

Urbanization promotes specific bacteria in freshwater microbiomes including potential pathogens.
Numberger, D. and Zoccarato, L. and Woodhouse, J. and Ganzert, L. and Sauer, S. and García Márquez, J.R. and Domisch, S. and Grossart, H.P. and Greenwood, A.D.
Science of the Total Environment 845 : 157321. 1 November 2022

Longitudinal retinal changes in MOGAD.
Oertel, F.C. and Sotirchos, E.S. and Zimmermann, H.G. and Motamedi, S. and Specovius, S. and Asseyer, E.S. and Chien, C. and Cook, L. and Vasileiou, E. and Filippatou, A. and Calabresi, P.A. and Saidha, S. and Pandit, L. and D'Cunha, A. and Outteryck, O. and Zéphir, H. and Pittock, S. and Flanagan, E.P. and Bhatti, M.T. and Rommer, P.S. and Bsteh, G. and Zrzavy, T. and Kuempfel, T. and Aktas, O. and Ringelstein, M. and Albrecht, P. and Ayzenberg, I. and Pakeerathan, T. and Knier, B. and Aly, L. and Asgari, N. and Soelberg, K. and Marignier, R. and Tilikete, C.F. and Calvo, A.C. and Villoslada, P. and Sanchez-Dalmau, B. and Martinez-Lapiscina, E.H. and Llufriu, S. and Green, A.J. and Yeaman, M.R. and Smith, T.J. and Brandt, A.U. and Chen, J. and Paul, F. and Havla, J.
Annals of Neurology 92 (3): 476-485. September 2022

Effect of atmospheric aging on soot particle toxicity in lung cell models at the air-liquid interface: differential toxicological impacts of biogenic and anthropogenic secondary organic aerosols (SOAs).
Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Martens, P. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Pardo, M. and Gröger, T. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Rudich, Y. and Zimmermann, R.
Environmental Health Perspectives 130 (2): 27003. 3 February 2022

Lack of evidence for participation of TMEM150C in sensory mechanotransduction.
Ojeda-Alonso, J. and Bégay, V. and Garcia-Contreras, J.A. and Campos-Pérez, A.F. and Purfürst, B. and Lewin, G.R.
Journal of General Physiology 154 (12): e202213098. 5 December 2022

Deep learning based liquid level extraction from video observations of gas-liquid flows.
Olbrich, M. and Riazy, L. and Kretz, T. and Leonard, T. and van Putten, D.S. and Bär, M. and Oberleithner, K. and Schmelter, S.
International Journal of Multiphase Flow 157 : 104247. December 2022

A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth.
Ong, Y.T. and Andrade, J. and Armbruster, M. and Shi, C. and Castro, M. and Costa, A.S.H. and Sugino, T. and Eelen, G. and Zimmermann, B. and Wilhelm, K. and Lim, J. and Watanabe, S. and Guenther, S. and Schneider, A. and Zanconato, F. and Kaulich, M. and Pan, D. and Braun, T. and Gerhardt, H. and Efeyan, A. and Carmeliet, P. and Piccolo, S. and Grosso, A.R. and Potente, M.
Nature Metabolism 4 (6): 672-682. June 2022

Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla, T. and Gollasch, B. and Kuich, P.H.J.L. and Klug, L. and Rahn, G. and Busjahn, A. and Spuler, S. and Boschmann, M. and Kirwan, J.A. and Luft, F.C. and Kempa, S.
Frontiers in Molecular Biosciences 9 : 1042231. 21 December 2022

Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.
Ortiz-Zapater, E. and Bagley, D.C. and Hernandez, V.L. and Roberts, L.B. and Maguire, T.J.A. and Voss, F. and Mertins, P. and Kirchner, M. and Peset-Martin, I. and Woszczek, G. and Rosenblatt, J. and Gotthardt, M. and Santis, G. and Parsons, M.
Nature Communications 13 (1): 6407. 27 October 2022

A computational model for prediction of ferritin and haemoglobin levels in blood donors.
Paalvast, Y. and Moazzen, S. and Sweegers, M. and Hogema, B. and Janssen, M. and van den Hurk, K.
British Journal of Haematology 199 (1): 143-152. October 2022

Biosynthetic potential of the global ocean microbiome.
Paoli, L. and Ruscheweyh, H.J. and Forneris, C.C. and Hubrich, F. and Kautsar, S. and Bhushan, A. and Lotti, A. and Clayssen, Q. and Salazar, G. and Milanese, A. and Carlström, C.I. and Papadopoulou, C. and Gehrig, D. and Karasikov, M. and Mustafa, H. and Larralde, M. and Carroll, L.M. and Sánchez, P. and Zayed, A.A. and Cronin, D.R. and Acinas, S.G. and Bork, P. and Bowler, C. and Delmont, T.O. and Gasol, J.M. and Gossert, A.D. and Kahles, A. and Sullivan, M.B. and Wincker, P. and Zeller, G. and Robinson, S.L. and Piel, J. and Sunagawa, S.
Nature 607 (7917): 111-118. 7 July 2022

Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells.
Pardo, M. and Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Schneider, E. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Karg, E. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Shalit, T. and Gröger, T. and Rüger, C.P. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Zimmermann, R. and Rudich, Y.
Environment International 166 : 107366. August 2022

Adoption of Transparency and Openness Promotion (TOP) guidelines across journals.
Patarčić, I. and Stojanovski, J.
Publications 10 (4): 46. 28 November 2022

A growth factor-expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15.
Patsalos, A. and Halasz, L. and Medina-Serpas, M.A. and Berger, W.K. and Daniel, B. and Tzerpos, P. and Kiss, M. and Nagy, G. and Fischer, C. and Simandi, Z. and Varga, T. and Nagy, L.
Journal of Experimental Medicine 219 (1): e20210420. 3 January 2022

The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
Paulmann, C. and Spallek, R. and Karpiuk, O. and Heider, M. and Schäffer, I. and Zecha, J. and Klaeger, S. and Walzik, M. and Öllinger, R. and Engleitner, T. and Wirth, M. and Keller, U. and Krönke, J. and Rudelius, M. and Kossatz, S. and Rad, R. and Kuster, B. and Bassermann, F.
EMBO Journal 41 (20): e110871. 17 October 2022

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K. and Leunig, A. and Kaiser, R. and Joppich, M. and Brambs, S. and Janjic, A. and Popp, O. and Nixdorf, D. and Fumagalli, V. and Schmidt, N. and Polewka, V. and Anjum, A. and Knottenberg, V. and Eivers, L. and Wange, L.E. and Gold, C. and Kirchner, M. and Muenchhoff, M. and Hellmuth, J.C. and Scherer, C. and Rubio-Acero, R. and Eser, T. and Deák, F. and Puchinger, K. and Kuhl, N. and Linder, A. and Saar, K. and Tomas, L. and Schulz, C. and Wieser, A. and Enard, W. and Kroidl, I. and Geldmacher, C. and von Bergwelt-Baildon, M. and Keppler, O.T. and Munschauer, M. and Iannacone, M. and Zimmer, R. and Mertins, P. and Hubner, N. and Hoelscher, M. and Massberg, S. and Stark, K. and Nicolai, L.
Nature Communications 13 (1): 1018. 23 February 2022

Quantitative phosphoproteomics of the angiotensin AT(2)-receptor signaling network identifies HDAC1 (Histone-Deacetylase-1) and p53 as mediators of antiproliferation and apoptosis.
Peluso, A.A.B. and Kempf, S.J. and Verano-Braga, T. and Rodrigues-Ribeiro, L. and Johansen, L.E. and Hansen, M.R. and Kitlen, G. and Haugaard, A.H. and Sumners, C. and Ditzel, H.J. and Santos, R.A. and Bader, M. and Larsen, M.R. and Steckelings, U.M.
Hypertension 79 (11): 2530-2541. November 2022

A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics.
Pennitz, P. and Kirsten, H. and Friedrich, V.D. and Wyler, E. and Goekeri, C. and Obermayer, B. and Heinz, G.A. and Mashreghi, M.F. and Büttner, M. and Trimpert, J. and Landthaler, M. and Suttorp, N. and Hocke, A.C. and Hippenstiel, S. and Tönnies, M. and Scholz, M. and Kuebler, W.M. and Witzenrath, M. and Hoenzke, K. and Nouailles, G.
European Respiratory Review 31 (165): 220056. 30 September 2022

Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Perea-Gil, I. and Seeger, T. and Bruyneel, A.A.N. and Termglinchan, V. and Monte, E. and Lim, E.W. and Vadgama, N. and Furihata, T. and Gavidia, A.A. and Arthur Ataam, J. and Bharucha, N. and Martinez-Amador, N. and Ameen, M. and Nair, P. and Serrano, R. and Kaur, B. and Feyen, D.A.M. and Diecke, S. and Snyder, M.P. and Metallo, C.M. and Mercola, M. and Karakikes, I.
European Heart Journal 43 (36): 3477-3489. 21 September 2022

Framework and baseline examination of the German National Cohort (NAKO).
Peters, A. and Peters, A. and Greiser, K.H. and Göttlicher, S. and Ahrens, W. and Albrecht, M. and Bamberg, F. and Bärnighausen, T. and Becher, H. and Berger, K. and Beule, A. and Boeing, H. and Bohn, B. and Bohnert, K. and Braun, B. and Brenner, H. and Bülow, R. and Castell, S. and Damms-Machado, A. and Dörr, M. and Ebert, N. and Ecker, M. and Emmel, C. and Fischer, B. and Franzke, C.W. and Gastell, S. and Giani, G. and Günther, M. and Günther, K. and Günther, K.P. and Haerting, J. and Haug, U. and Heid, I.M. and Heier, M. and Heinemeyer, D. and Hendel, T. and Herbolsheimer, F. and Hirsch, J. and Hoffmann, W. and Holleczek, B. and Hölling, H. and Hörlein, A. and Jöckel, K.H. and Kaaks, R. and Karch, A. and Karrasch, S. and Kartschmit, N. and Kauczor, H.U. and Keil, T. and Kemmling, Y. and Klee, B. and Klüppelholz, B. and Kluttig, A. and Kofink, L. and Köttgen, A. and Kraft, D. and Krause, G. and Kretz, L. and Krist, L. and Kühnisch, J. and Kuß, O. and Legath, N. and Lehnich, A.T. and Leitzmann, M. and Lieb, W. and Linseisen, J. and Loeffler, M. and Macdonald, A. and Maier-Hein, K.H. and Mangold, N. and Meinke-Franze, C. and Meisinger, C. and Melzer, J. and Mergarten, B. and Michels, K.B. and Mikolajczyk, R. and Moebus, S. and Mueller, U. and Nauck, M. and Niendorf, T. and Nikolaou, K. and Obi, N. and Ostrzinski, S. and Panreck, L. and Pigeot, I. and Pischon, T. and Pschibul-Thamm, I. and Rathmann, W. and Reineke, A. and Roloff, S. and Rujescu, D. and Rupf, S. and Sander, O. and Schikowski, T. and Schipf, S. and Schirmacher, P. and Schlett, C.L. and Schmidt, B. and Schmidt, G. and Schmidt, M. and Schöne, G. and Schulz, H. and Schulze, M.B. and Schweig, A. and Sedlmeier, A.M. and Selder, S. and Six-Merker, J. and Sowade, R. and Stang, A. and Stegle, O. and Steindorf, K. and Stübs, G. and Swart, E. and Teismann, H. and Thiele, I. and Thierry, S. and Ueffing, M. and Völzke, H. and Waniek, S. and Weber, A. and Werner, N. and Wichmann, H.E. and Willich, S.N. and Wirkner, K. and Wolf, K. and Wolff, R. and Zeeb, H. and Zinkhan, M. and Zschocke, J.
European Journal of Epidemiology 37 (10): 1107-1124. October 2022

Treatment with ribociclib shows favourable immunomodulatory effects in patients with hormone receptor-positive breast cancer-findings from the RIBECCA trial.
Peuker, C.A. and Yaghobramzi, S. and Grunert, C. and Keilholz, L and Gjerga, E. and Hennig, S. and Schaper, S. and Na, I.K. and Keller, U. and Brucker, S. and Decker, T. and Fasching, P. and Fehm, T. and Janni, W. and Kümmel, S. and Schneeweiss, A. and Schuler, M. and Lüftner, D. and Busse, A.
European Journal of Cancer 162 : 45-55. February 2022

A RAS-independent biomarker panel to reliably predict response to MEK inhibition in colorectal cancer.
Pfohl, U. and Loskutov, J. and Bashir, S. and Kühn, R. and Herter, P. and Templin, M. and Mamlouk, S. and Belanov, S. and Linnebacher, M. and Bürtin, F. and Vetter, M. and Reinhard, C. and Wedeken, L. and Regenbrecht, C.R.A.
Cancers 14 (13): 3252. 1 July 2022

Pre-diagnostic circulating resistin concentrations are not associated with colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study.
Pham, T.T. and Nimptsch, K. and Aleksandrova, K. and Jenab, M. and Reichmann, R. and Wu, K. and Tjønneland, A. and Kyrø, C. and Schulze, M.B. and Kaaks, R. and Katzke, V. and Palli, D. and Pasanisi, F. and Ricceri, F. and Tumino, R. and Krogh, V. and Roodhart, J. and Castilla, J. and Sánchez, M.J. and Colorado-Yohar, S.M. and Harbs, J. and Rutegård, M. and Papier, K. and Aglago, E.K. and Dimou, N. and Mayen-Chacon, A.L. and Weiderpass, E. and Pischon, T.
Cancers 14 (22): 5499. 9 November 2022

Engineering, decoding and systems-level characterization of chimpanzee cytomegalovirus.
Phan, Q.V. and Bogdanow, B. and Wyler, E. and Landthaler, M. and Liu, F. and Hagemeier, C. and Wiebusch, L.
PLoS Pathogens 18 (1): e1010193. 4 January 2022

Nitric oxide metabolites: associations with cardiovascular biomarkers and clinical parameters in patients with HFpEF.
Piatek, K. and Feuerstein, A. and Zach, V. and Rozados da Conceicao, C. and Beblo, A. and Belyavskiy, E. and Pieske-Kraigher, E. and Krannich, A. and Schwedhelm, E. and Hinz, S. and Pieske, B. and Edelmann, F.
ESC Heart Failure 9 (6): 3961-3972. December 2022

Tuning the 3D microenvironment of reprogrammed tubule cells enhances biomimetic modeling of polycystic kidney disease.
Pichler, R. and Rizzo, L. and Tröndle, K. and Bühler, M. and Brucker, H. and Müller, A.L. and Grand, K. and Farè, S. and Viau, A. and Kaminski, M.M. and Kuehn, E.W. and Koch, F. and Zimmermann, S. and Koltay, P. and Lienkamp, S.S.
Biomaterials 291 : 121910. December 2022

RNA modification mapping with JACUSA2.
Piechotta, M. and Naarmann-de Vries, I.S. and Wang, Q. and Altmüller, J. and Dieterich, C.
Genome Biology 23 (1): 115. 16 May 2022

Rabies anterograde monosynaptic tracing allows identification of postsynaptic circuits receiving distinct somatosensory input.
Pimpinella, S. and Sauve, I. and Dietrich, S. and Zampieri, N.
Neuroscience 491 : 75-86. 21 May 2022

Gut microbiome composition in obese and non-obese persons: a systematic review and meta-analysis.
Pinart, M. and Dötsch, A. and Schlicht, K. and Laudes, M. and Bouwman, J. and Forslund, S.K. and Pischon, T. and Nimptsch, K.
Nutrients 14 (1): 12. 1 January 2022

Cardiovascular magnetic resonance in children with suspected myocarditis: current practice and applicability of adult protocols.
Pitak, B. and Opgen-Rhein, B. and Schubert, S. and Reineker, K. and Wiegand, G. and Boecker, D. and Rentzsch, A. and Ruf, B. and Özcan, S. and Wannenmacher, B. and Pickardt, T. and Seidel, F. and Messroghli, D.
Cardiology in the Young 32 (12): 1957-1965. December 2022

EACVI survey on hypertrophic cardiomyopathy.
Podlesnikar, T. and Cardim, N. and Ajmone Marsan, N. and D'Andrea, A. and Cameli, M. and Popescu, B.A. and Schulz-Menger, J. and Stankovic, I. and Toplisek, J. and Maurer, G. and Haugaa, K.H. and Dweck, M.R.
European Heart Journal - Cardiovascular Imaging 23 (5): 590-597. May 2022

Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.
Poetz, F. and Lebedeva, S. and Schott, J. and Lindner, D. and Ohler, U. and Stoecklin, G.
Genome Biology 23 (1): 193. 12 September 2022

Antigen receptor-engineered Tregs inhibit CNS autoimmunity in cell therapy using non-redundant immune mechanisms in mice.
Pohar, J. and O'Connor, R. and Manfroi, B. and Behi, M.E. and Jouneau, L. and Boudinot, P. and Bunse, M. and Uckert, W. and Luka, M. and Ménager, M. and Liblau, R. and Anderton, S.M. and Fillatreau, S.
European Journal of Immunology 52 (8): 1335-1349. August 2022

Neuroligins in neurodevelopmental conditions: how mouse models of de novo mutations can help us link synaptic function to social behavior.
Pohl, T. and Hörnberg, H.
Neuronal Signaling 6 (2): NS20210030. June 2022

Missense variant E1295K of sodium channel SCN5A associated with recurrent ventricular fibrillation and myocardial inflammation.
Poller, W. and Escher, F. and Haas, J. and Heidecker, B. and Schultheiss, H.P. and Attanasio, P. and Skurk, C. and Haghikia, A. and Meder, B. and Klaassen, S.
JACC: Case Reports 4 (5): 280-286. 2 March 2022

Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders.
Porubsky, D. and Höps, W. and Ashraf, H. and Hsieh, P.H. and Rodriguez-Martin, B. and Yilmaz, F. and Ebler, J. and Hallast, P. and Maggiolini, F.A.M. and Harvey, W.T. and Henning, B. and Audano, P.A. and Gordon, D.S. and Ebert, P. and Hasenfeld, P. and Benito, E. and Zhu, Q. and Lee, C. and Antonacci, F. and Steinrücken, M. and Beck, C.R. and Sanders, A.D. and Marschall, T. and Eichler, E.E. and Korbel, J.O.
Cell 185 (11): 1986-2005. 26 May 2022

Long-term imaging reveals behavioral plasticity during C. elegans dauer exit.
Preusser, F. and Neuschulz, A. and Junker, J.P. and Rajewsky, N. and Preibisch, S.
BMC Biology 20 (1): 277. 13 December 2022

Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics.
Pryszlak, A. and Wenzel, T. and Seitz, K.W. and Hildebrand, F. and Kartal, E. and Cosenza, M.R. and Benes, V. and Bork, P. and Merten, C.A.
Cell Reports Methods 2 (1): 100137. 24 January 2022

Targeting Wnt/β-catenin signaling by TET1/FOXO4 inhibits metastatic spreading and self-renewal of cancer stem cells in gastric cancer.
Qi, J. and Cui, D. and Wu, Q.N. and Zhao, Q. and Chen, Z.H. and Li, L. and Birchmeier, W. and Yu, Y. and Tao, R.
Cancers 14 (13): 3232. 30 June 2022

The genomic and transcriptional landscape of primary central nervous system lymphoma.
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FIRE-9 - PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer.
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CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
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Symmetry 14 (2): 244. February 2022

Cultivation-independent genomes greatly expand taxonomic-profiling capabilities of mOTUs across various environments.
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Proposal for post hoc quality control in instrumented motion analysis using markerless motion capture: development and usability study.
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RGB-Depth camera-based assessment of motor capacity: normative data for six standardized motor tasks.
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Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
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Clonal expansion and epigenetic inheritance of long-lasting NK cell memory.
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Nature Immunology 23 (11): 1551-1563. November 2022

Enriched environment attenuates enhanced trait anxiety in association with normalization of aberrant neuro-inflammatory events.
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International Journal of Molecular Sciences 23 (21): 13052. 27 October 2022

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Fragmentation, circadian amplitude, and fractal pattern of daily-living physical activity in people with multiple sclerosis: is there relevant information beyond the total amount of physical activity?
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Epigenetic targeting of transposon relics: beating the dead horses of the genome?
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The brain integrates proprioceptive information to ensure robust locomotion.
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International Journal of Molecular Sciences 23 (9): 4941. 29 April 2022

Serum dihydrotestosterone is associated with adverse myocardial remodeling in patients with aortic valve stenosis before and after aortic valve replacement.
Schafstedde, M. and Nordmeyer, J. and Berger, F. and Knosalla, C. and Mertins, P. and Regitz-Zagrosek, V. and Kuehne, T. and Kraus, M. and Nordmeyer, S.
American Journal of Physiology Heart and Circulatory Physiology 323 (5): H949-H957. November 2022

Adolescence is a sensitive period for prefrontal microglia to act on cognitive development.
Schalbetter, S.M. and von Arx, A.S. and Cruz-Ochoa, N. and Dawson, K. and Ivanov, A. and Mueller, F.S. and Lin, H.Y. and Amport, R. and Mildenberger, W. and Mattei, D. and Beule, D. and Földy, C. and Greter, M. and Notter, T. and Meyer, U.
Science Advances 8 (9): eabi6672. 4 March 2022

Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice.
Schepanski, S. and Chini, M. and Sternemann, V. and Urbschat, C. and Thiele, K. and Sun, T. and Zhao, Y. and Poburski, M. and Woestemeier, A. and Thieme, M.T. and Zazara, D.E. and Alawi, M. and Fischer, N. and Heeren, J. and Vladimirov, N. and Woehler, A. and Puelles, V.G. and Bonn, S. and Gagliani, N. and Hanganu-Opatz, I.L. and Arck, P.C.
Nature Communications 13 (1): 4571. 5 August 2022

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.
Schick, M. and Zhang, L. and Maurer, S. and Maurer, H.C. and Isaakaidis, K. and Schneider, L. and Patra, U. and Schunck, K. and Rohleder, E. and Hofstetter, J. and Baluapuri, A. and Scherger, A.K. and Slotta-Huspenina, J. and Hettler, F. and Weber, J. and Engleitner, T. and Maresch, R. and Slawska, J. and Lewis, R. and Istvanffy, R. and Habringer, S. and Steiger, K. and Baiker, A. and Oostendorp, R.A.J. and Miething, C. and Lenhof, H.P. and Bassermann, F. and Chapuy, B. and Wirth, M. and Wolf, E. and Rad, R. and Müller, S. and Keller, U.
Nature Communications 13 (1): 281. 12 January 2022

Hypo- und Hypernatriämien auf der Intensivstation : Fallstricke des Volumenmanagements [Hypo- and hypernatremia in the intensive care unit : pitfalls in volume management].
Schilling, J. and Compton, F. and Schmidt-Ott, K.
Wiener klinisches Magazin 25 : 32-37. 10 January 2022

Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance.
Schlautmann, L.P. and Lackmann, J.W. and Altmüller, J. and Dieterich, C. and Boehm, V. and Gehring, N.H.
Nucleic Acids Research 50 (10): 5899-5918. 10 June 2022

Capillary gel electrophoresis (CGE) for quality control of plasmid DNA in gene therapy: quality control of 20 years stored GMP-grade plasmid DNA.
Schmeer, M. and Schleef, M. and Shankar, R. and Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521 (3): 317-328. 23 June 2022

The synaptic scaffold protein MPP2 interacts with GABA(A) receptors at the periphery of the postsynaptic density of glutamatergic synapses.
Schmerl, B. and Gimber, N. and Kuropka, B. and Stumpf, A. and Rentsch, J. and Kunde, S.A. and von Sivers, J. and Ewers, H. and Schmitz, D. and Freund, C. and Schmoranzer, J. and Rademacher, N. and Shoichet, S.A.
PLoS Biology 20 (3): e3001503. 21 March 2022

Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker.
Schmid, F. and Dahlmann, M. and Röhrich, H. and Kobelt, D. and Hoffmann, J. and Burock, S. and Walther, W. and Stein, U.
British Journal of Cancer 127 (4): 675-685. 1 September 2022

B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
Schmid, V.K. and Khadour, A. and Ahmed, N. and Brandl, C. and Nitschke, L. and Rajewsky, K. and Jumaa, H. and Hobeika, E.
Haematologica 107 (8): 1796-1814. August 2022

Somatic mosaicism in STAG2-associated cohesinopathies: Expansion of the genotypic and phenotypic spectrum.
Schmidt, J. and Dreha-Kulaczewski, S. and Zafeiriou, M.P. and Schreiber, M.K. and Wilken, B. and Funke, R. and Neuhofer, C.M. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Biskup, S. and Li, Y. and Zimmermann, W.H. and Kaulfuß, S. and Yigit, G. and Wollnik, B.
Frontiers in Cell and Developmental Biology 10 : 1025332. 16 November 2022

Familial cleft tongue caused by a unique translation initiation codon variant in TP63.
Schmidt, J. and Schreiber, G. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Li, Y. and Kaulfuß, S. and Funke, R. and Wilken, B. and Yigit, G. and Wollnik, B.
European Journal of Human Genetics 30 (2): 211-218. February 2022

Drivers and determinants of strain dynamics following fecal microbiota transplantation.
Schmidt, T.S.B. and Li, S.S. and Maistrenko, O.M. and Akanni, W. and Coelho, L.P. and Dolai, S. and Fullam, A. and Glazek, A.M. and Hercog, R. and Herrema, H. and Jung, F. and Kandels, S. and Orakov, A. and Thielemann, R. and von Stetten, M. and Van Rossum, T. and Benes, V. and Borody, T.J. and de Vos, W.M. and Ponsioen, C.Y. and Nieuwdorp, M. and Bork, P.
Nature Medicine 28 (9): 1902-1912. September 2022

Prävention des akuten Nierenversagens [Prevention of acute kidney injury].
Schmidt-Ott, K.M. and Swolinsky, J.
Deutsche Medizinische Wochenschrift 147 (5): 236-245. March 2022

Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
Schmiester, M. and Maier, R. and Riedel, R. and Durek, P. and Frentsch, M. and Kolling, S. and Mashreghi, M.F. and Jenq, R. and Zhang, L. and Peterson, C.B. and Bullinger, L. and Chang, H.D. and Na, I.K.
Gut Microbes 14 (1): e2081475. 29 May 2022

Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.
Schmiester, M. and Tranter, E. and Lorusso, A. and Blaschke, F. and Geisel, D. and Bullinger, L. and Damm, F. and Na, I.K.
BMC Cardiovascular Disorders 22 (1): 31. 4 February 2022

PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M. and Schwarzer, A. and Jayavelu, A.K. and Hsu, C.J. and Kirkpatrick, J. and Döhner, K. and Perner, F. and Eifert, T. and Huber, N. and Arreba-Tutusaus, P. and Dolnik, A. and Assi, S.A. and Nafria, M. and Jiang, L. and Dai, Y.T. and Chen, Z. and Chen, S.J. and Kellaway, S.G. and Ptasinska, A. and Ng, E.S. and Stanley, E.G. and Elefanty, A.G. and Buschbeck, M. and Bierhoff, H. and Brodt, S. and Matziolis, G. and Fischer, K.D. and Hochhaus, A. and Chen, C.W. and Heidenreich, O. and Mann, M. and Lane, S.W. and Bullinger, L. and Ori, A. and von Eyss, B. and Bonifer, C. and Heidel, F.
Blood 139 (7): 1080-1097. 17 February 2022

Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD.
Schroeder-Castagno, M. and Del Rio-Serrato, A. and Wilhelm, A. and Romero-Suárez, S. and Schindler, P. and Alvarez-González, C. and Duchow, A.S. and Bellmann-Strobl, J. and Ruprecht, K. and Hastermann, M. and Grütz, G. and Wildemann, B. and Jarius, S. and Schmitz-Hübsch, T. and Paul, F. and Infante-Duarte, C.
Journal of Neuroinflammation 19 (1): 239. 1 October 2022

Helicobacter pylori - neue Aspekte kommender Leitlinien [Helicobacter pylori - new aspects of forthcoming guidelines].
Schulz, C. and Fischbach, W. and Sigal, M. and Schütte, K. and Suerbaum, S. and Malfertheiner, P.
Internist 63 (4): 367-371. 1 March 2022

In prostate cancer cells cytokines are early responders to gravitational changes occurring in parabolic flights.
Schulz, H. and Dietrichs, D. and Wehland, M. and Corydon, T.J. and Hemmersbach, R. and Liemersdorf, C. and Melnik, D. and Hübner, N. and Saar, K. and Infanger, M. and Grimm, D.
International Journal of Molecular Sciences 23 (14): 7876. 17 July 2022

Data augmentation via partial nonlinear registration for brain-age prediction.
Schulz, M.A. and Koch, A. and Guarino, V.E. and Kainmueller, D. and Ritter, K.
Lecture Notes in Computer Science 13596 : 169-178. 2022

SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F. and de Castro Cuadrat, R.R. and Wyler, E. and Wurmus, R. and Deter, A. and Quedenau, C. and Dohmen, J. and Faxel, M. and Borodina, T. and Blume, A. and Freimuth, J. and Meixner, M. and Grau, J.H. and Liere, K. and Hackenbeck, T. and Zietzschmann, F. and Gnirss, R. and Böckelmann, U. and Uyar, B. and Franke, V. and Barke, N. and Altmüller, J. and Rajewsky, N. and Landthaler, M. and Akalin, A.
Science of the Total Environment 853 : 158931. 20 December 2022

Whole-body magnetic resonance imaging in the large population-based German National Cohort study: predictive capability of automated image quality assessment for protocol repetitions.
Schuppert, C. and von Krüchten, R. and Hirsch, J.G. and Rospleszcz, S. and Hoinkiss, D.C. and Selder, S. and Köhn, A. and von Stackelberg, O. and Peters, A. and Völzke, H. and Kröncke, T. and Niendorf, T. and Forsting, M. and Hosten, N. and Hendel, T. and Pischon, T. and Jöckel, K.H. and Kaaks, R. and Bamberg, F. and Kauczor, H.U. and Günther, M. and Schlett, C.L.
Investigative Radiology 57 (7): 478-487. 1 July 2022

Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine.
Schwab, K. and Chasapopoulou, Z. and Frahm, S. and Magbagbeolu, M. and Cranston, A. and Harrington, C.R. and Wischik, C.M. and Theuring, F. and Riedel, G.
Cellular Signalling 97 : 110386. September 2022

On the relation between input and output distributions of scRNA-seq experiments.
Schwabe, D. and Falcke, M.
Bioinformatics 38 (5): 1336-1343. 1 March 2022

Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline: a randomized clinical tTrial.
Schwarz, C. and Benson, G.S. and Horn, N. and Wurdack, K. and Grittner, U. and Schilling, R. and Märschenz, S. and Köbe, T. and Hofer, S.J. and Magnes, C. and Stekovic, S. and Eisenberg, T. and Sigrist, S.J. and Schmitz, D. and Wirth, M. and Madeo, F. and Flöel, A.
JAMA Network Open 5 (5): e2213875. 26 May 2022

Eating patterns during pregnancy and postpartum and their association with diet quality and energy intake.
Schwedhelm, C. and Lipsky, L.M. and Temmen, C.D. and Nansel, T.R.
Nutrients 14 (6): 1167. 10 March 2022

Evidence of neural crest cell origin of a DICER1 mutant CNS sarcoma in a child with DICER1 syndrome and NRAS-mutant neurocutaneous melanosis.
Schweizer, L. and Hartmann, W. and Koch, A. and Nunninger, M. and Thomale, U.W. and Pennacchietti, V. and Tietze, A. and Horn, D. and Pajtler, K.W. and Hirsch, S. and Wieland, I. and Deubzer, H. and Rossi, R. and Hernáiz Driever, P. and von Hoff, K. and von Zezschwitz, B.
Neuropathology and Applied Neurobiology 48 (6): e12830. October 2022

3D-printed tissue-simulating phantoms for near-infrared fluorescence imaging of rheumatoid diseases.
Schädel-Ebner, S. and Hirsch, O. and Gladytz, T. and Gutkelch, D. and Licha, K. and Berger, J. and Grosenick, D.
Journal of Biomedical Optics 27 (7): 074702. July 2022

Highly conserved interaction profiles between clinically relevant mutants of the cytomegalovirus CDK-like kinase pUL97 and human cyclins: functional significance of cyclin H.
Schütz, M. and Müller, R. and Socher, E. and Wangen, C. and Full, F. and Wyler, E. and Wong, D. and Scherer, M. and Stamminger, T. and Chou, S. and Rawlinson, W.D. and Hamilton, S.T. and Sticht, H. and Marschall, M.
International Journal of Molecular Sciences 23 (19): 11814. 5 October 2022

Evaluation of lake sedimentary ancient DNA metabarcoding to assess fungal biodiversity in Arctic paleoecosystems.
Seeber, P.A. and Hippel, B. and Kauserud, H. and Löber, U. and Stoof‐Leichsenring, K.R. and Herzschuh, U. and Epp, L.S.
Environmental DNA 4 (5): 1150-1163. September 2022

Pathogenic variants in cardiomyopathy disorder genes underlie pediatric myocarditis - Further impact of heterozygous immune disorder gene variants?
Seidel, F. and Laser, K.T. and Klingel, K. and Dartsch, J. and Theisen, S. and Pickardt, T. and Holtgrewe, M. and Gärtner, A. and Berger, F. and Beule, D. and Milting, H. and Schubert, S. and Klaassen, S. and Kühnisch, J.
Journal of Cardiovascular Development and Disease 9 (7): 216. 5 July 2022

Clinical characteristics and outcome of biopsy-proven myocarditis in children - Results of the German prospective multicentre registry "MYKKE".
Seidel, F. and Opgen-Rhein, B. and Rentzsch, A. and Boehne, M. and Wannenmacher, B. and Boecker, D. and Reineker, K. and Grafmann, M. and Wiegand, G. and Hecht, T. and Kiski, D. and Fischer, M. and Papakostas, K. and Ruf, B. and Kramp, J. and Khalil, M. and Kaestner, M. and Steinmetz, M. and Fischer, G. and Özcan, S. and Freudenthal, N. and Schweigmann, U. and Hellwig, R. and Pickardt, T. and Klingel, K. and Messroghli, D. and Schubert, S.
International Journal of Cardiology 357 : 95-104. 15 June 2022

Compensatory upregulation of anti-beta-adrenergic receptor antibody levels might prevent heart failure presentation in pediatric myocarditis.
Seidel, F. and Scheibenbogen, C. and Heidecke, H. and Opgen-Rhein, B. and Pickardt, T. and Klingel, K. and Berger, F. and Messroghli, D. and Schubert, S.
Frontiers in Pediatrics 10 : 881208. 28 April 2022

Optocoder: computational decoding of spatially indexed bead arrays.
Senel, E. and Rajewsky, N. and Karaiskos, N.
NAR Genomics and Bioinformatics 4 (2): lqac042. June 2022

A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants.
Shahan, R. and Hsu, C.W. and Nolan, T.M. and Cole, B.J. and Taylor, I.W. and Greenstreet, L. and Zhang, S. and Afanassiev, A. and Vlot, A.H.C. and Schiebinger, G. and Benfey, P.N. and Ohler, U.
Developmental Cell 57 (4): 543-560. 28 February 2022

K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.
Shearer, R.F. and Typas, D. and Coscia, F. and Schovsbo, S. and Kruse, T. and Mund, A. and Mailand, N.
EMBO Journal 41 (9): e110145. 2 May 2022

SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition.
Shih, A.Z.L. and Chen, Y.C. and Speckmann, T. and Søndergaard, E. and Schürmann, A. and Verchere, C.B. and Willnow, T.E.
Molecular Metabolism 65 : 101585. November 2022

Amelioration of endotoxemia by a synthetic analog of Omega-3 epoxyeicosanoids.
Shikuma, A. and Kami, D. and Maeda, R. and Suzuki, Y. and Sano, A. and Taya, T. and Ogata, T. and Konkel, A. and Matoba, S. and Schunck, W.H. and Gojo, S.
Frontiers in Immunology 13 : 825171. 24 February 2022

Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.
Shum, M. and Segawa, M. and Gharakhanian, R. and Viñuela, A. and Wortham, M. and Baghdasarian, S. and Wolf, D.M. and Sereda, S.B. and Nocito, L. and Stiles, L. and Zhou, Z. and Gutierrez, V. and Sander, M. and Shirihai, O.S. and Liesa, M.
Molecular Metabolism 55 : 101403. January 2022

Graph neural networks for learning molecular excitation spectra.
Singh, K. and Münchmeyer, J. and Weber, L. and Leser, U. and Bande, A.
Journal of Chemical Theory and Computation 18 (7): 4408-4417. 12 July 2022

A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish.
Singh, S.P. and Chawla, P. and Hnatiuk, A. and Kamel, M. and Silva, L.D. and Spanjaard, B. and Eski, S.E. and Janjuha, S. and Olivares-Chauvet, P. and Kayisoglu, O. and Rost, F. and Bläsche, J. and Kränkel, A. and Petzold, A. and Kurth, T. and Reinhardt, S. and Junker, J.P. and Ninov, N.
Development 149 (2): dev199853. January 2022

Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy.
Sinha Ray, S. and Dutta, D. and Dennys, C. and Powers, S. and Roussel, F. and Lisowski, P. and Glažar, P. and Zhang, X. and Biswas, P. and Caporale, J.R. and Rajewsky, N. and Bickle, M. and Wein, N. and Bellen, H.J. and Likhite, S. and Marcogliese, P.C. and Meyer, K.C.
Cell Reports 41 (10): 111751. 6 December 2022

CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment.
Skroblyn, T. and Joedicke, J.J. and Pfau, M. and Krüger, K. and Bourquin, J.P. and Izraeli, S. and Eckert, C. and Höpken, U.E.
Journal of Pathology 258 (1): 12-25. September 2022

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić, S. and Prada-Medina, C.A. and Landoulsi, Z. and Ghelfi, J. and Delcambre, S. and Dietrich, C. and Jarazo, J. and Henck, J. and Balachandran, S. and Pachchek, S. and Morris, C.M. and Antony, P. and Timmermann, B. and Sauer, S. and Pereira, S.L. and Schwamborn, J.C. and May, P. and Grünewald, A. and Spielmann, M.
Brain 145 (3): 964-978. March 2022

Dysregulated autoantibodies targeting vaso- and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity.
Sotzny, F. and Filgueiras, I.S. and Kedor, C. and Freitag, H. and Wittke, K. and Bauer, S. and Sepúlveda, N. and Mathias da Fonseca, D.L. and Baiocchi, G.C. and Marques, A.H.C. and Kim, M. and Lange, T. and Plaça, D.R. and Luebber, F. and Paulus, F.M. and De Vito, R. and Jurisica, I. and Schulze-Forster, K. and Paul, F. and Bellmann-Strobl, J. and Rust, R. and Hoppmann, U. and Shoenfeld, Y. and Riemekasten, G. and Heidecke, H. and Cabral-Marques, O. and Scheibenbogen, C.
Frontiers in Immunology 13 : 981532. 27 September 2022

Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
Specker, E. and Matthes, S. and Wesolowski, R. and Schütz, A. and Grohmann, M. and Alenina, N. and Pleimes, D. and Mallow, K. and Neuenschwander, M. and Gogolin, A. and Weise, M. and Pfeifer, J. and Ziebart, N. and Heinemann, U. and von Kries, J.P. and Nazaré, M. and Bader, M.
Journal of Medicinal Chemistry 65 (16): 11126-11149. 25 August 2022

Berlin Registry of Neuroimmunological entities (BERLimmun): protocol of a prospective observational study.
Sperber, P.S. and Brandt, A.U. and Zimmermann, H.G. and Bahr, L.S. and Chien, C. and Rekers, S. and Mähler, A. and Böttcher, C. and Asseyer, S. and Duchow, A.S. and Bellmann-Strobl, J. and Ruprecht, K. and Paul, F. and Schmitz-Hübsch, T.
BMC Neurology 22 (1): 479. 14 December 2022

mRNA-mediated delivery of gene editing tools to human primary muscle stem cells.
Stadelmann, C. and Di Francescantonio, S. and Marg, A. and Müthel, S. and Spuler, S. and Escobar, H.
Molecular Therapy - Nucleic Acids 28 : 47-57. 14 June 2022

Nationwide registry-based analysis of infective endocarditis risk after pulmonary valve replacement.
Stammnitz, Clara and Huscher, Dörte and Bauer, Ulrike M M and Urban, Aleksandra and Nordmeyer, Johannes and Schubert, Stephan and Photiadis, Joachim and Berger, Felix and Klaassen, S.
Journal of the American Heart Association 11 (5): e022231. 18 February 2022

Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas.
Staudacher, J.J. and Arnold, A. and Kühl, A.A. and Pötzsch, M. and Daum, S. and Winterfeld, M. and Berg, E. and Hummel, M. and Rau, B. and Stein, U. and Treese, C.
BMC Cancer 22 (1): 953. 5 September 2022

DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M. and Denker, S. and Schmitt, C.A.
Cancers 14 (6): 1453. 11 March 2022

Obesity is associated with myelin oligodendrocyte glycoprotein antibody-associated disease in acute optic neuritis.
Stiebel-Kalish, H. and Rubarth, K. and Shouchane-Blum, K. and Tiosano, A. and Lotan, I. and Hellmann, M.A. and Wilf-Yarkoni, A. and Bialer, O. and Flanagan, E.P. and Pittock, S.J. and Bhatti, M.T. and Schmitz-Hübsch, T. and Paul, F. and Asseyer, S. and Chen, J.J.
Scientific Reports 12 (1): 21312. 9 December 2022

Lifetime and current depression in the German National Cohort (NAKO).
Streit, F. and Zillich, L. and Frank, J. and Kleineidam, L. and Wagner, M. and Baune, B.T. and Klinger-König, J. and Grabe, H.J. and Pabst, A. and Riedel-Heller, S.G. and Schmiedek, F. and Schmidt, B. and Erhardt, A. and Deckert, J. and Rietschel, M. and Berger, K.
World Journal of Biological Psychiatry 24 (10): 865-880. 17 February 2022

Comorbidities rather than older age define outcome in adult patients with tumors of the Ewing sarcoma family.
Striefler, J.K. and Schmiester, M. and Brandes, F. and Dörr, A. and Pahl, S. and Kaul, D. and Rau, D. and Dobrindt, E.M. and Koulaxouzidis, G. and Bullinger, L. and Märdian, S. and Flörcken, A.
Cancer Medicine 11 (17): 3213-3225. September 2022

MCT1 is a predictive marker for lenalidomide maintenance therapy in multiple myeloma.
Stroh, J. and Seckinger, A. and Heider, M. and Rudelius, M. and Eichner, R. and Schick, M. and Slawska, J. and Emde, M. and Salwender, H. and Bertsch, U. and Goldschmidt, H. and Weisel, K.C. and Scheid, C. and Keller, U. and Hose, D. and Bassermann, F.
Blood Advances 6 (2): 515-520. 25 January 2022

Cell type diversity in a developing octopus brain.
Styfhals, R. and Zolotarov, G. and Hulselmans, G. and Spanier, K.I. and Poovathingal, S. and Elagoz, A.M. and De Winter, S. and Deryckere, A. and Rajewsky, N. and Ponte, G. and Fiorito, G. and Aerts, S. and Seuntjens, E.
Nature Communications 13 (1): 7392. 30 November 2022

Pan-claudin family interactome analysis reveals shared and specific interactions.
Suarez Artiles, L. and Breiderhoff, T. and Girardello, R. and Gonschior, H. and Rodius, S. and Lesur, A. and Reimer, U. and Ramberger, E. and Perez-Hernandez, D. and Müller, D. and Mertins, P. and Dittmar, G.
Cell Reports 41 (6): 111588. 8 November 2022

Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
Subramanian, S. and Busch, C.J.L. and Molawi, K. and Geirsdottir, L. and Maurizio, J. and Vargas Aguilar, S. and Belahbib, H. and Gimenez, G. and Yuda, R.A.A. and Burkon, M. and Favret, J. and Gholamhosseinian Najjar, S. and de Laval, B. and Kandalla, P.K. and Sarrazin, S. and Alexopoulou, L. and Sieweke, M.H.
Nature Immunology 23 (3): 458-468. March 2022

Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer.
Sugimoto, Y. and Ratcliffe, P.J.
Nature Structural & Molecular Biology 29 (9): 871–880. September 2022

Male carriers of HLA-C*04:01 have increased risk of cardiac injury in COVID-19.
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Nature Communications 13 (1): 7497. 5 December 2022

Can fractal dimensions objectivize gastropod shell morphometrics? A case study from Lake Lugu (SW China).
Wiese, R. and Harrington, K. and Hartmann, K. and Hethke, M. and Rintelen, T. and Zhang, H. and Zhang, L.J. and Riedel, F.
Ecology and Evolution 12 (3): e8622. February 2022

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C. and Doebele, C. and Zindel, A. and Lee, K.S. and Rieke, S.A. and Ceribelli, M. and Comoglio, F. and Phelan, J.D. and Wang, J.Q. and Pikman, Y. and Jahn, D. and Häupl, B. and Schneider, C. and Scheich, S. and Tosto, F.A. and Bohnenberger, H. and Stauder, P. and Schnütgen, F. and Slabicki, M. and Coulibaly, Z.A. and Wolf, S. and Bojarczuk, K. and Chapuy, B. and Brandts, C.H. and Stroebel, P. and Lewis, C.A. and Engelke, M. and Xu, X. and Kim, H. and Dang, T.H. and Schmitz, R. and Hodson, D.J. and Stegmaier, K. and Urlaub, H. and Serve, H. and Schmitt, C.A. and Kreuz, F. and Knittel, G. and Rabinowitz, J.D. and Reinhardt, H.C. and Vander Heiden, M.G. and Thomas, C. and Staudt, L.M. and Zenz, T. and Oellerich, T.
Blood 139 (4): 538-553. 27 January 2022

Network meta-analysis of food and drug administration-approved treatment options for adults with aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorder.
Wingerchuk, D.M. and Zhang, I. and Kielhorn, A. and Royston, M. and Levy, M. and Fujihara, K. and Nakashima, I. and Tanvir, I. and Paul, F. and Pittock, S.J.
Neurology and Therapy 11 (1): 123-135. March 2022

Long-term observation of the frequency of secondary colorectal cancer and other malignancies in tyrosine kinase inhibitor treated chronic myeloid leukemia patients and controls.
Winkelmann, N. and Schwarz, M. and Hildebrandt, B. and Henke, O. and Bullinger, L. and Na, I.K. and Stintzing, S. and le Coutre, P.
eJHaem: The Official Journal of the British Society for Haematology 3 (3): 949-953. August 2022

EBAG9-silencing exerts an immune checkpoint function without aggravating adverse effects.
Wirges, A. and Bunse, M. and Joedicke, J.J. and Blanc, E. and Gudipati, V. and Moles, M.W. and Shiku, H. and Beule, D. and Huppa, J.B. and Höpken, U.E. and Rehm, A.
Molecular Therapy 30 (11): 3358-3378. 2 November 2022

Alterations of NK cell phenotype during pregnancy in multiple sclerosis.
Wisgalla, A. and Ramien, C. and Streitz, M. and Schlickeiser, S. and Lupu, A.R. and Diemert, A. and Tolosa, E. and Arck, P.C. and Bellmann-Strobl, J. and Siebert, N. and Heesen, C. and Paul, F. and Friese, M.A. and Infante-Duarte, C. and Gold, S.M.
Frontiers in Immunology 13 : 907994. 4 July 2022

Paired donor and recipient immunophenotyping in allogeneic hematopoietic stem cell transplantation: a cellular network approach.
Wittenbecher, F. and Lesch, S. and Kolling, S. and Blau, I.W. and Vuong, L. and Borchert, F. and Movasshagi, K. and Tietze-Bürger, C. and Penack, O. and Ahn, J. and Bullinger, L. and Frentsch, M. and Na, I.K.
Frontiers in Immunology 13 : 874499. 23 May 2022

Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.
Wizenty, J. and Müllerke, S. and Kolesnichenko, M. and Heuberger, J. and Lin, M. and Fischer, A.S. and Mollenkopf, H.J. and Berger, H. and Tacke, F. and Sigal, M.
EMBO Journal 41 (13): e109996. 4 July 2022

Mutations in TAF8 cause a neurodegenerative disorder.
Wong, K.M. and Jepsen, W.M. and Efthymiou, S. and Salpietro, V. and Sanchez-Castillo, M. and Yip, J. and Kriouile, Y. and Diegmann, S. and Dreha-Kulaczewski, S. and Altmüller, J. and Thiele, H. and Nürnberg, P. and Toosi, M.B. and Akhondian, J. and Ghayoor Karimiani, E. and Hummel-Abmeier, H. and Huppke, B. and Houlden, H. and Gärtner, J. and Maroofian, R. and Huppke, P.
Brain 145 (9): 3022-3034. September 2022

An interdisciplinary approach to characterize peanut-allergic patients - first data from the FOOD@ consortium.
Worm, M. and Alexiou, A. and Höfer, V. and Birkner, T. and Jeanrenaud, A.C.S.N. and Fauchère, F. and Pazur, K. and Steinert, C. and Arnau-Soler, A. and Banerjee, P. and Diefenbach, A. and Dobbertin-Welsch, J. and Dölle-Bierke, S. and Francuzik, W. and Ghauri, A. and Heller, S. and Kalb, B. and Löber, U. and Marenholz, I. and Markó, L. and Scheffel, J. and Potapenko, O. and Roll, St. and Lau, S. and Lee, Y.A. and Braun, J. and Thiel, A. and Babina, M. and Altrichter, S. and Forslund, S.K. and Beyer, K.
Clinical and Translational Allergy 12 (10): e12197. October 2022

A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Wu, Y. and Biswas, D. and Usaite, I. and Angelova, M. and Boeing, S. and Karasaki, T. and Veeriah, S. and Czyzewska-Khan, J. and Morton, C. and Joseph, M. and Hessey, S. and Reading, J. and Georgiou, A. and Al-Bakir, M. and McGranahan, N. and Jamal-Hanjani, M. and Hackshaw, A. and Quezada, S.A. and Hayday, A.C. and Swanton, C.
Nature Cancer 3 (6): 696-709. June 2022

Der Physikochemiker Gerhard Geiseler und die Haffkrankheit.
Wunderlich, V.
Mitteilungen der Wilhelm-Ostwald-Gesellschaft 27 : 42-52. 2022

The transcription factor EB (TFEB) sensitizes the heart to chronic pressure overload.
Wundersitz, S. and Pablo Tortola, C. and Schmidt, S. and Oliveira Vidal, R. and Kny, M. and Hahn, A. and Zanders, L. and Katus, H.A. and Sauer, S. and Butter, C. and Luft, F.C. and Müller, O.J. and Fielitz, J.
International Journal of Molecular Sciences 23 (11): 5943. 25 May 2022

Radiofrequency electromagnetic fields cause non-temperature-induced physical and biological effects in cancer cells.
Wust, P. and Veltsista, P.D. and Oberacker, E. and Yavvari, P. and Walther, W. and Bengtsson, O. and Sterner-Kock, A. and Weinhart, M. and Heyd, F. and Grabowski, P. and Stintzing, S. and Heinrich, W. and Stein, U. and Ghadjar, P.
Cancers 14 (21): 5349. 30 October 2022

Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single cell transcriptomics.
Wyler, E. and Adler, J.M. and Eschke, K. and Teixeira Alves, G. and Peidli, S. and Pott, F. and Kazmierski, J. and Michalick, L. and Kershaw, O. and Bushe, J. and Andreotti, S. and Pennitz, P. and Abdelgawad, A. and Postmus, D. and Goffinet, C. and Kreye, J. and Reincke, S.M. and Prüss, H. and Blüthgen, N. and Gruber, A.D. and Kuebler, W.M. and Witzenrath, M. and Landthaler, M. and Nouailles, G. and Trimpert, J.
Molecular Therapy 30 (5): 1952-1965. 4 May 2022

Analysis of copy number variation in men with non-obstructive azoospermia.
Wyrwoll, M.J. and Wabschke, R. and Röpke, A. and Wöste, M. and Ruckert, C. and Perrey, S. and Rotte, N. and Hardy, J. and Astica, L. and Lupianez, D.G. and Wistuba, J. and Westernströer, B. and Schlatt, S. and Berman, A.J. and Müller, A.M. and Kliesch, S. and Yatsenko, A.N. and Tüttelmann, F. and Friedrich, C.
Andrology 10 (8): 1593-1604. November 2022

Intraretinal layer segmentation using cascaded compressed U-Nets.
Yadav, S.K. and Kafieh, R. and Zimmermann, H.G. and Kauer-Bonin, J. and Nouri-Mahdavi, K. and Mohammadzadeh, V. and Shi, L. and Kadas, E.M. and Paul, F. and Motamedi, S. and Brandt, A.U.
Journal of Imaging 8 (5): 139. 17 May 2022

A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation.
Yanchus, C. and Drucker, K.L. and Kollmeyer, T.M. and Tsai, R. and Winick-Ng, W. and Liang, M. and Malik, A. and Pawling, J. and De Lorenzo, S.B. and Ali, A. and Decker, P.A. and Kosel, M.L. and Panda, A. and Al-Zahrani, K.N. and Jiang, L. and Browning, J.W.L. and Lowden, C. and Geuenich, M. and Hernandez, J.J. and Gosio, J.T. and Ahmed, M. and Loganathan, S.K. and Berman, J. and Trcka, D. and Michealraj, K.A. and Fortin, J. and Carson, B. and Hollingsworth, E.W. and Jacinto, S. and Mazrooei, P. and Zhou, L. and Elia, A. and Lupien, M. and He, H.H. and Murphy, D.J. and Wang, L. and Abyzov, A. and Dennis, J.W. and Maass, P.G. and Campbell, K. and Wilson, M.D. and Lachance, D.H. and Wrensch, M. and Wiencke, J. and Mak, T. and Pennacchio, L.A. and Dickel, D.E. and Visel, A. and Wrana, J. and Taylor, M.D. and Zadeh, G. and Dirks, P. and Eckel-Passow, J.E. and Attisano, L. and Pombo, A. and Ida, C.M. and Kvon, E.Z. and Jenkins, R.B. and Schramek, D.
Science 378 (6615): 68-78. 7 October 2022

Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells.
Yang, M. and Yu, H. and Yu, X. and Liang, S. and Hu, Y. and Luo, Y. and Izsvák, Z. and Sun, C. and Wang, J.
Cell Stem Cell 29 (3): 400-418.e13. 3 March 2022

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y. and Du Jiang, P. and Chao, B.N. and Cagdas, D. and Kubo, S. and Balasubramaniyam, A. and Zhang, Y. and Shadur, B. and NaserEddin, A. and Folio, L.R. and Schwarz, B. and Bohrnsen, E. and Zheng, L. and Lynberg, M. and Gottlieb, S. and Leney-Greene, M.A. and Park, A.Y. and Tezcan, I. and Akdogan, A. and Gocmen, R. and Onder, S. and Rosenberg, A. and Soilleux, E.J. and Johnson, E. and Jackson, P.K. and Demeter, J. and Chauvin, S.D. and Paul, F. and Selbach, M. and Bulut, H. and Clatworthy, M.R. and Tuong, Z.K. and Zhang, H. and Stewart, B.J. and Bosio, C.M. and Stepensky, P. and Clare, S. and Ganesan, S. and Pascall, J.C. and Daumke, O. and Butcher, G.W. and McMichael, A.J. and Simon, A.K. and Lenardo, M.J.
Journal of Experimental Medicine 219 (6): e20201405. 6 June 2022

Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state.
Yigit, G. and Sheffer, R. and Daana, M. and Li, Y. and Kaygusuz, E. and Mor-Shakad, H. and Altmüller, J. and Nürnberg, P. and Douiev, L. and Kaulfuss, S. and Burfeind, P. and Wollnik, B. and Brockmann, K.
Journal of Medical Genetics 59 (6): 549-553. 20 May 2022

The host peritoneal cavity harbors prominent memory Th2 and early recall responses to an intestinal nematode.
Yordanova, I.A. and Jürchott, K. and Steinfelder, S. and Vogt, K. and Krüger, U. and Kühl, A.A. and Sawitzki, B. and Hartmann, S.
Frontiers in Immunology 13 : 842870. 28 March 2022

Analysis of single-cell transcriptome data in drosophila.
Yousefian, S. and Musillo, M.J. and Bageritz, J.
Methods in Molecular Biology 2540 (3): 93-111. 19 August 2022

Recapitulating early human development with 8C-like cells.
Yu, X. and Liang, S. and Chen, M. and Yu, H. and Li, R. and Qu, Y. and Kong, X. and Guo, R. and Zheng, R. and Izsvak, Z. and Sun, C. and Yang, M. and Wang, J.
Cell Reports 39 (12): 110994. 21 June 2022

Tph2 gene expression defines ethanol drinking behavior in mice.
Zaniewska, M. and Mosienko, V. and Bader, M. and Alenina, N.
Cells 11 (5): 874. 3 March 2022

2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death.
Zeppenfeld, K. and Tfelt-Hansen, J. and de Riva, M. and Winkel, B.G. and Behr, E.R. and Blom, N.A. and Charron, P. and Corrado, D. and Dagres, N. and de Chillou, C. and Eckardt, L. and Friede, T. and Haugaa, K.H. and Hocini, M. and Lambiase, P.D. and Marijon, E. and Merino, J.L. and Peichl, P. and Priori, S.G. and Reichlin, T. and Schulz-Menger, J. and Sticherling, C. and Tzeis, S. and Verstrael, A. and Volterrani, M.
European Heart Journal 43 (40): 3997-4126. 21 October 2022

Proton-gated anion transport governs macropinosome shrinkage.
Zeziulia, M. and Blin, S. and Schmitt, F.W. and Lehmann, M. and Jentsch, T.J.
Nature Cell Biology 24 (6): 885-895. June 2022

Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.
Zhai, Y. and Singh, P. and Dolnik, A. and Brazda, P. and Atlasy, N. and Del Gaudio, N. and Döhner, K. and Döhner, H. and Minucci, S. and Martens, J. and Altucci, L. and Megchelenbrink, W. and Bullinger, L. and Stunnenberg, H.G.
Molecular Cancer 21 (1): 166. 19 August 2022

Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Zhang, S. and Cao, S. and Gong, M. and Zhang, W. and Zhang, W. and Zhu, Z. and Wu, S. and Yue, Y. and Qian, W. and Ma, Q. and Wang, S. and Wang, Z.
Cancer Biology & Therapy 23 (1): 336-347. 22 April 2022

RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis.
Zhang, Y. and Wang, C. and Sun, M. and Jin, Y. and Braz, C.U. and Khatib, H. and Hacker, T.A. and Liss, M. and Gotthardt, M. and Granzier, H. and Ge, Y. and Guo, W.
FASEB Journal 36 (5): e22302. May 2022

Role of TRPC6 in kidney damage after acute ischemic kidney injury.
Zheng, Z. and Tsvetkov, D. and Bartolomaeus, T.U.P. and Erdogan, C. and Krügel, U. and Schleifenbaum, J. and Schaefer, M. and Nürnberg, B. and Chai, X. and Ludwig, F.A. and N'diaye, G. and Köhler, M.B. and Wu, K. and Gollasch, M. and Markó, L.
Scientific Reports 12 (1): 3038. 22 February 2022

In vivo inhibition of TRPC6 by SH045 attenuates renal fibrosis in a New Zealand Obese (NZO) mouse model of metabolic syndrome.
Zheng, Z. and Xu, Y. and Krügel, U. and Schaefer, M. and Grune, T. and Nürnberg, B. and Köhler, M.B. and Gollasch, M. and Tsvetkov, D. and Marko, L.
International Journal of Molecular Sciences 23 (12): 6870. 20 June 2022

A preclinical study on brugada syndrome with a CACNB2 variant using human cardiomyocytes from induced pluripotent stem cells.
Zhong, R. and Schimanski, T. and Zhang, F. and Lan, H. and Hohn, A. and Xu, Q. and Huang, M. and Liao, Z. and Qiao, L. and Yang, Z. and Li, Y. and Zhao, Z. and Li, X. and Rose, L. and Albers, S. and Maywald, L. and Müller, J. and Dinkel, H. and Saguner, A. and Janssen, J.W.G. and Telugu, N.S. and Xi, Y. and Lang, S. and Kleinsorge, M. and Duru, F. and Zhou, X. and Diecke, S. and Cyganek, L. and Akin, I. and El-Battrawy, I.
International Journal of Molecular Sciences 23 (15): 8313. 1 August 2022

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.
Zhou, D. and Borsa, M. and Puleston, D.J. and Zellner, S. and Capera, J. and Sanderson, S. and Schifferer, M. and Hester, S.S. and Ge, X. and Fischer, R. and Jostins, L. and Behrends, C. and Alsaleh, G. and Simon, A.K.
Nature Communications 13 (1): 5174. 2 September 2022

Autophagy takes it all - autophagy inducers target immune aging.
Zinecker, H. and Simon, A.K.
Disease Models & Mechanisms 15 (1): dmm049345. 31 January 2022

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U. and Milek, M. and Minia, I. and Vieira-Vieira, C.H. and Müller, S. and Mastrobuoni, G. and Hazapis, O.G. and Del Giudice, S. and Schwefel, D. and Bley, N. and Voigt, F. and Chao, J.A. and Kempa, S. and Hüttelmaier, S. and Selbach, M. and Landthaler, M.
Nature Communications 13 (1): 2727. 18 May 2022

MicroRNAs are deeply linked to the emergence of the complex octopus brain.
Zolotarov, G. and Fromm, B. and Legnini, I. and Ayoub, S. and Polese, G. and Maselli, V. and Chabot, P.J. and Vinther, J. and Styfhals, R. and Seuntjens, E. and Di Cosmo, A. and Peterson, K.J. and Rajewsky, N.
Science Advances 8 (47): eadd9938. 25 November 2022

The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G. and Vanzo, R. and Amitash, S. and Martín-Doncel, E. and Coscia, F. and Mund, A. and Lerdrup, M. and Benada, J. and Boos, D. and Toledo, L.
Molecular Cell 82 (18): 3350-3365. 15 September 2022

Disease relevance of rare VPS13B missense variants for neurodevelopmental Cohen syndrome.
Zorn, M. and Kühnisch, J. and Bachmann, S. and Seifert, W.
Scientific Reports 12 (1): 9686. 11 June 2022

Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling law.
Zou, X. and Schaefke, B. and Li, Y. and Jia, F. and Sun, W. and Li, G. and Liang, W. and Reif, T. and Heyd, F. and Gao, Q. and Tian, S. and Li, Y. and Tang, Y. and Fang, L. and Hu, Y. and Chen, W.
Life Science Alliance 5 (4): e202101333. April 2022

Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros.
Zywitza, V. and Frahm, S. and Krüger, N. and Weise, A. and Göritz, F. and Hermes, R. and Holtze, S. and Colleoni, S. and Galli, C. and Drukker, M. and Hildebrandt, T.B. and Diecke, S.
iScience 25 (11): 105414. 18 November 2022

Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction.
Zywitza, V. and Rusha, E. and Shaposhnikov, D. and Ruiz-Orera, J. and Telugu, N. and Rishko, V. and Hayashi, M. and Michel, G. and Wittler, L. and Stejskal, J. and Holtze, S. and Göritz, F. and Hermes, R. and Wang, J. and Izsvák, Z. and Colleoni, S. and Lazzari, G. and Galli, C. and Hildebrandt, T.B. and Hayashi, K. and Diecke, S. and Drukker, M.
Scientific Reports 12 (1): 3100. 8 March 2022

Altered nuclear architecture in blood cells from Huntington's disease patients.
de Castro, I.J. and Toner, B. and Xie, S.Q. and Swingland, J. and Hodges, A. and Tabrizi, S.J. and Turkheimer, F. and Pombo, A. and Khalil, A.
Neurological Sciences 43 (1): 379-385. January 2022

SMOG 2 and OpenSMOG: extending the limits of structure-based models.
de Oliveira, A.B. and Contessoto, V.G. and Hassan, A. and Byju, S. and Wang, A. and Wang, Y. and Dodero-Rojas, E. and Mohanty, U. and Noel, J.K. and Onuchic, J.N. and Whitford, P.C.
Protein Science 31 (1): 158-172. January 2022

The genomic and spatial mobility of extrachromosomal DNA and its implications for cancer therapy.
van Leen, E. and Brückner, L. and Henssen, A.G.
Nature Genetics 54 (2): 107-114. February 2022

State-dependent signatures of anti-N-methyl-d-aspartate receptor encephalitis.
von Schwanenflug, N. and Krohn, S. and Heine, J. and Paul, F. and Prüss, H. and Finke, C.
Brain Communications 4 (1): fcab298. 1 February 2022

Soluble urokinase plasminogen activator receptor levels are associated with severity of fibrosis in patients with primary sclerosing cholangitis.
Özdirik, B. and Maibier, M. and Scherf, M. and Nicklaus, J.M. and Frohme, J. and Puengel, T. and Meyer Zum Büschenfelde, D. and Tacke, F. and Mueller, T. and Sigal, M.
Journal of Clinical Medicine 11 (9): 2479. 28 April 2022

Book Section

Salt, aldosterone, and the renin-angiotensin system in pregnancy.
Dechend, R. and Lamarca, B. and Davidge, S.T.
In: Chesley's Hypertensive Disorders in Pregnancy. Elsevier / Academic Press, 335-353. ISBN 978-0-12-818417-2 2022

Comprehensive identification of plant polyphenols by LC-MS.
Fernández-Ochoa, Á. and de la Luz Cádiz-Gurrea, M. and Segura Carretero, A.
In: Mass spectrometry for food analysis. Methods and Protocols in Food Science . Humana, New York, NY, 31-42. ISBN 978-1-0716-2106-6 26 June 2022

Mathematical and bioinformatic tools for cell tracking.
Hirsch, P. and Epstein, L. and Guignard, L.
In: Cell Movement in Health and Disease. Academic Press, London, 341-361. ISBN 978-0-323-90195-6 2022

Glial cells: neuroglia.
Kettenmann, H. and Verkhratsky, A.
In: Neuroscience in the 21st century: from basic to clinical (3rd ed.). Springer Nature, Cham, 825-860. ISBN 978-3-030-88831-2 2022

Epidemiologie der Adipositas.
Nimptsch, K. and Pischon, T.
In: Handbuch Essstörungen und Adipositas. Springer Berlin, Heidelberg, Berlin, Heidelberg, Germany, 445-451. ISBN 9783662635438 26 August 2022

Arzneimittelversorgung bei Multipler Sklerose.
Paul, F. and Berthele, A.
In: Arzneimittel-Kompass 2022: Qualität der Arzneimittelversorgung. Springer, Berlin, Heidelberg, 139-159. ISBN 978-3-662-66040-9 2022

Conference or Workshop Item

Dataset debt in biomedical language modeling.
Fries, J.A. and Seelam, N. and Altay, G. and Weber, L. and Kang, M. and Datta, D. and Su, R. and Garda, S. and Wang, B. and Ott, S. and Samwald, M. and Kusa, W.
In: 2022 Challenges and Perspectives in Creating Large Language Models, 27 May 2022, Virtual, Dublin. May 2022

Fusion moves for graph matching.
Hutschenreiter, L. and Haller, S. and Feineis, L. and Rother, C. and Kainmüller, D. and Savchynskyy, B.
In: 2021 IEEE/CVF International Conference on Computer Vision (ICCV), 10-17 Oct 2021, Montreal, QC, Canada. 28 February 2022

Radiofrequency antenna helmet array for thermal magnetic resonance of brain tumours at 297 MHz.
Rahimi, F. and Berangi, M. and Eigentler, T.W. and Nurzed, B. and Millward, J.M. and Schuhmann, R. and Niendorf, T.
In: 2022 3rd URSI Atlantic and Asia Pacific Radio Science Meeting (AT-AP-RASC), 30 May - 04 Jun 2022, Gran Canaria, Spain. 6 July 2022

Panoptic segmentation with highly imbalanced semantic labels.
Rumberger, J.L. and Baumann, E. and Hirsch, P. and Janowczyk, A. and Zlobec, I. and Kainmueller, D.
In: 2022 IEEE International Symposium on Biomedical Imaging Challenges (ISBIC), 28-31 March 2022, Kolkata, India. 17 August 2022

How shift equivariance impacts metric learning for instance segmentation.
Rumberger, J.L. and Yu, X. and Hirsch, P. and Dohmen, M. and Guarino, V.E. and Mokarian, A. and Mais, L. and Funke, J. and Kainmueller, D.
In: 2021 IEEE/CVF International Conference on Computer Vision (ICCV), 10-17 Oct 2021, Montreal, QC, Canada. 28 February 2022


Drosophila: Methods and Protocols.
Dahmann, C., ed.
Methods in Molecular Biology, 2540 . Springer / Humana Press, New York, NY, USA. ISBN 9781071625408 2022

Gene therapy of cancer : methods and protocols.
Walther, Wolfgang, ed.
Methods in Molecular Biology, 2521 (3). Springer / Humana Press, New York, NY. ISBN 9781071624401 2022


Single cell metabolism: current and future trends.
Ali, A. and Davidson, S. and Fraenkel, E. and Gilmore, I. and Hankemeier, T. and Kirwan, J.A. and Lane, A.N. and Lanekoff, I. and Larion, M. and McCall, L.I. and Murphy, M. and Sweedler, J.V. and Zhu, C.
Metabolomics 18 (10): 77. 1 October 2022

Age-related mechanisms in the context of rheumatic disease.
Alsaleh, G. and Richter, F.C. and Simon, A.K.
Nature Reviews Rheumatology 18 (12): 694-710. December 2022

The monocyte, a maestro in the tumor microenvironment (TME) of breast cancer.
Amer, H.T. and Stein, U. and El Tayebi, H.M.
Cancers 14 (21): 5460. 7 November 2022

The role of respiratory microbiota in the protection against viral diseases: respiratory commensal bacteria as next-generation probiotics for COVID-19.
Andrade, B.G.N. and Cuadrat, R.R.C. and Tonetti, F.R. and Kitazawa, H. and Villena, J.
Bioscience of Microbiota, Food and Health 41 (3): 94-102. 1 July 2022

Management of malignant dysgerminoma of the ovary.
Arndt, T. and Taube, E.T. and Deubzer, H.E. and Rothe, K. and Calaminus, G. and Sehouli, J. and Pietzner, K.
European Journal of Gynaecological Oncology 43 (2): 353-362. 15 April 2022

Crosstalk between the renin-angiotensin, complement and kallikrein-kinin systems in inflammation.
Bekassy, Z. and Lopatko Fagerström, I. and Bader, M. and Karpman, D.
Nature Reviews Immunology 22 (7): 411-428. July 2022

Tissue engineering for the diaphragm and its various therapeutic possibilities - a systematic review.
Boehm, A.K. and Hillebrandt, K.H. and Dziodzio, T. and Krenzien, F. and Neudecker, J. and Spuler, S. and Pratschke, J. and Sauer, I.M. and Andreas, M.N.
Advanced Therapeutics 5 (8): 2100247. 18 August 2022

Metaproteomics approach and pathway modulation in obesity and diabetes: a narrative review.
Calabrese, F.M. and Porrelli, A. and Vacca, M. and Comte, B. and Nimptsch, K. and Pinart, M. and Pischon, T. and Pujos-Guillot, E. and De Angelis, M.
Nutrients 14 (1): 47. January 2022

Cardiac metabolism in HFpEF: from fuel to signalling.
Capone, F. and Sotomayor-Flores, C. and Bode, D. and Wang, R. and Rodolico, D. and Strocchi, S. and Schiattarella, G.G.
Cardiovascular Research 118 (18): 3556-3575. December 2022

Oxidative RNA damage in the pathogenesis and treatment of type 2 diabetes.
Chen, X. and Yu, H. and Li, Z. and Ye, W. and Liu, Z. and Gao, J. and Wang, Y. and Li, X. and Zhang, L. and Alenina, N. and Bader, M. and Ding, H. and Li, P. and Aung, L.H.H.
Frontiers in Physiology 13 : 725919. 28 March 2022

Physical mechanisms of chromatin spatial organization.
Chiariello, A.M. and Bianco, S. and Esposito, A. and Fiorillo, L. and Conte, M. and Irani, E. and Musella, F. and Abraham, A. and Prisco, A. and Nicodemi, M.
FEBS Journal 289 (5): 1180-1190. March 2022

Single cell‐ and spatial 'omics revolutionize physiology.
Conrad, T. and Altmüller, J.
Acta Physiologica : e13848. 2 June 2022

Polymer models of chromatin imaging data in single cells.
Conte, M. and Chiariello, A.M. and Abraham, A. and Bianco, S. and Esposito, A. and Nicodemi, M. and Matteuzzi, T. and Vercellone, F.
Algorithms 15 (9): 330. 16 September 2022

Glycans in HIV-1 vaccine design - engaging the shield.
Deimel, L.P. and Xue, X. and Sattentau, Q.J.
Trends in Microbiology 30 (9): 866-881. September 2022

Personalisierte Medizin in der Kinderonkologie: Wo stehen wir heute?
Deubzer, H.E. and Schulte, J.H. and Eggert, A.
TumorDiagnostik & Therapie 43 (01): 29-44. February 2022

The physics of DNA folding: polymer models and phase-separation.
Esposito, A. and Abraham, A. and Conte, M. and Vercellone, F. and Prisco, A. and Bianco, S. and Chiariello, A.M.
Polymers 14 (9): 1918. 9 May 2022

Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies.
Frantz, S. and Hundertmark, M.J. and Schulz-Menger, J. and Bengel, F.M. and Bauersachs, J.
European Heart Journal 43 (27): 2549-2561. 14 July 2022

Cosmeceutical potential of major tropical and subtropical fruit by-products for a sustainable revalorization.
García-Villegas, A. and Rojas-García, A. and Villegas-Aguilar, M.C. and Fernández-Moreno, P. and Fernández-Ochoa, Á. and Cádiz-Gurrea, M.L. and Arráez-Román, D. and Segura-Carretero, A.
Antioxidants 11 (2): 203. 21 January 2022

Vaccine-associated enhanced disease and pathogenic human coronaviruses.
Gartlan, C. and Tipton, T. and Salguero, F.J. and Sattentau, Q. and Gorringe, A. and Carroll, M.W.
Frontiers in Immunology 13 : 882972. 4 April 2022

Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications.
Gawałko, M. and Agbaedeng, T.A. and Saljic, A. and Mueller, D.N. and Wilck, N. and Schnabel, R. and Penders, J. and Rienstra, M. and van Gelder, I. and Jespersen, T. and Schotten, U. and Crijns, H.J.G.M. and Kalman, J.M. and Sanders, P. and Nattel, S. and Dobrev, D. and Linz, D.
Cardiovascular Research 118 (11): 2415–2427. July 2022

Wie Kochsalz Mitochondrien beeinflusst.
Geisberger, S.
BIOspektrum 28 (4): 387-389. June 2022

Leveraging visual outcome measures to advance therapy development in neuroimmunologic disorders.
Graves, J.S. and Oertel, F.C. and Van der Walt, A. and Collorone, S. and Sotirchos, E.S. and Pihl-Jensen, G. and Albrecht, P. and Yeh, E.A. and Saidha, S. and Frederiksen, J. and Newsome, S.D. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 9 (2): e1126. March 2022

Refining AML treatment: the role of genetics in response and resistance evaluation to new agents.
Halik, A. and Arends, C.M. and Bullinger, L. and Damm, F. and Frick, M.
Cancers 14 (7): 1689. 26 March 2022

Acute kidney injury biomarkers in the single cell transcriptomic era.
Hinze, C. and Schmidt-Ott, K.M.
American Journal of Physiology Cell Physiology 323 (5): C1430-C1443. 9 November 2022

Mechanisms of spermidine-induced autophagy and geroprotection.
Hofer, S.J. and Simon, A.K. and Bergmann, M. and Eisenberg, T. and Kroemer, G. and Madeo, F.
Nature Aging 2 (12): 1112-1129. December 2022

Once upon a dish: the next frontier in engineering multicellular systems.
Huch, M. and Gouti, M.
Development 149 (20): dev200744. 15 October 2022

Small molecule inhibitors for hepatocellular carcinoma: advances and challenges.
Kamal, M.A. and Mandour, Y.M. and Abd El-Aziz, M.K. and Stein, U. and El Tayebi, H.M.
Molecules 27 (17): 5537. 1 September 2022

Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management.
Kirwan, J.A. and Gika, H. and Beger, R.D. and Bearden, D. and Dunn, W.B. and Goodacre, R. and Theodoridis, G. and Witting, M. and Yu, L.R. and Wilson, I.D.
Metabolomics 18 (9): 70. 27 August 2022

Left ventricular noncompaction in children: the role of genetics, morphology, and function for outcome.
Klaassen, S. and Kühnisch, J. and Schultze-Berndt, A. and Seidel, F.
Journal of Cardiovascular Development and Disease 9 (7): 206. 30 June 2022

Hidden agenda - the involvement of endoplasmic reticulum stress and unfolded protein response in inflammation-induced muscle wasting.
Kny, M. and Fielitz, J.
Frontiers in Immunology 13 : 878755. 9 May 2022

The gut microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS).
König, R.S. and Albrich, W.C. and Kahlert, C.R. and Bahr, L.S. and Löber, U. and Vernazza, P. and Scheibenbogen, C. and Forslund, S.K.
Frontiers in Immunology 12 : 628741. 3 January 2022

Neuroophthalmologische Präsentation der Retrobulbärneuritis im Rahmen der Myelin-Oligodendrozyten-Glykoprotein-Antikörper-assoziierten Erkrankung [Neuro-ophthalmological presentation of optic neuritis in myelin oligodendrocyte glycoprotein antibody-associated disease].
Lin, T.Y. and Asseyer, S. and Buenrostro, G.S. and Feldmann, K. and Hamann, S. and Paul, F. and Zimmermann, H.G.
Klinische Monatsblatter fur Augenheilkunde 239 (11): 1305-1314. 21 November 2022

Regulation of early cerebellar development.
Lowenstein, E. and Cui, K. and Hernandez-Miranda, L.R.
FEBS Journal 290 (11): 2786-2804. June 2022

Infectious complications of targeted drugs and biotherapies in acute leukemia. Clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL), a joint venture of the European Group for Blood and Marrow Transplantation (EBMT), the European Organization for Research and Treatment of Cancer (EORTC), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN).
Maschmeyer, G. and Bullinger, L. and Garcia-Vidal, C. and Herbrecht, R. and Maertens, J. and Menna, P. and Pagano, L. and Thiebaut-Bertrand, A. and Calandra, T.
Leukemia 36 (5): 1215-1226. May 2022

Physiological functions of intracellular protein degradation.
McShane, E. and Selbach, M.
Annual Review of Cell and Developmental Biology 38 : 241-262. October 2022

The genetic basis of Moyamoya disease.
Mertens, R. and Graupera, M. and Gerhardt, H. and Bersano, A. and Tournier-Lasserve, E. and Mensah, M.A. and Mundlos, S. and Vajkoczy, P.
Translational Stroke Research 13 (1): 25-45. February 2022

Diagnostik der Neuromyelitis-optica-Spektrum-Erkrankung (NMOSD) und der MOG-Antikörper-assoziierten Erkrankung (MOGAD) [Diagnosis of neuromyelitis optica spectrum disorder (NMOSD) and MOG Antibody-associated disease (MOGAD)].
Mewes, D. and Kuchling, J. and Schindler, P. and Khalil, A.A.A. and Jarius, S. and Paul, F. and Chien, C.
Klinische Monatsblatter fur Augenheilkunde 239 (11): 1315-1324. November 2022

Microglia states and nomenclature: A field at its crossroads.
Paolicelli, R.C. and Sierra, A. and Stevens, B. and Tremblay, M.E. and Aguzzi, A. and Ajami, B. and Amit, I. and Audinat, E. and Bechmann, I. and Bennett, M. and Bennett, F. and Bessis, A. and Biber, K. and Bilbo, S. and Blurton-Jones, M. and Boddeke, E. and Brites, D. and Brône, B. and Brown, G.C. and Butovsky, O. and Carson, M.J. and Castellano, B. and Colonna, M. and Cowley, S.A. and Cunningham, C. and Davalos, D. and De Jager, P.L. and de Strooper, B. and Denes, A. and Eggen, B.J.L. and Eyo, U. and Galea, E. and Garel, S. and Ginhoux, F. and Glass, C.K. and Gokce, O. and Gomez-Nicola, D. and González, B. and Gordon, S. and Graeber, M.B. and Greenhalgh, A.D. and Gressens, P. and Greter, M. and Gutmann, D.H. and Haass, C. and Heneka, M.T. and Heppner, F.L. and Hong, S. and Hume, D.A. and Jung, S. and Kettenmann, H. and Kipnis, J. and Koyama, R. and Lemke, G. and Lynch, M. and Majewska, A. and Malcangio, M. and Malm, T. and Mancuso, R. and Masuda, T. and Matteoli, M. and McColl, B.W. and Miron, V.E. and Molofsky, A.V. and Monje, M. and Mracsko, E. and Nadjar, A. and Neher, J.J. and Neniskyte, U. and Neumann, H. and Noda, M. and Peng, B. and Peri, F. and Perry, V.H. and Popovich, P.G. and Pridans, C. and Priller, J. and Prinz, M. and Ragozzino, D. and Ransohoff, R.M. and Salter, M.W. and Schaefer, A. and Schafer, D.P. and Schwartz, M. and Simons, M. and Smith, C.J. and Streit, W.J. and Tay, T.L. and Tsai, L.H. and Verkhratsky, A. and von Bernhardi, R. and Wake, H. and Wittamer, V. and Wolf, S.A. and Wu, L.J. and Wyss-Coray, T.
Neuron 110 (21): 3458-3483. 2 November 2022

Mitochondrial a kinase anchor proteins in cardiovascular health and disease: a review article on behalf of the Working Group on Cellular and Molecular Biology of the Heart of the Italian Society of Cardiology.
Paolillo, R. and D’Apice, S. and Schiattarella, G.G. and Ameri, P. and Borzacchiello, D. and Catalucci, D. and Chimenti, C. and Crotti, L. and Sciarretta, S. and Torella, D. and Feliciello, A. and Perrino, C.
International Journal of Molecular Sciences 23 (14): 7691. 12 July 2022

Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance.
Pecorino, L.T. and Verhaak, R.G.W. and Henssen, A. and Mischel, P.S.
Biochemical Society Transactions 50 (6): 1911-1920. December 2022

Formation and maintenance of the natural bypass vessels of the brain.
Perovic, T. and Harms, C. and Gerhardt, H.
Frontiers in Cardiovascular Medicine 9 : 778773. 22 March 2022

Diagnosis and classification of optic neuritis.
Petzold, A. and Fraser, C.L. and Abegg, M. and Alroughani, R. and Alshowaeir, D. and Alvarenga, R. and Andris, C. and Asgari, N. and Barnett, Y. and Battistella, R. and Behbehani, R. and Berger, T. and Bikbov, M.M. and Biotti, D. and Biousse, V. and Boschi, A. and Brazdil, M. and Brezhnev, A. and Calabresi, P.A. and Cordonnier, M. and Costello, F. and Cruz, F.M. and Cunha, L.P. and Daoudi, S. and Deschamps, R. and de Seze, J. and Diem, R. and Etemadifar, M. and Flores-Rivera, J. and Fonseca, P. and Frederiksen, J. and Frohman, E. and Frohman, T. and Tilikete, C.F. and Fujihara, K. and Gálvez, A. and Gouider, R. and Gracia, F. and Grigoriadis, N. and Guajardo, J.M. and Habek, M. and Hawlina, M. and Martínez-Lapiscina, E.H. and Hooker, J. and Hor, J.Y. and Howlett, W. and Huang-Link, Y. and Idrissova, Z. and Illes, Z. and Jancic, J. and Jindahra, P. and Karussis, D. and Kerty, E. and Kim, H.J. and Lagrèze, W. and Leocani, L. and Levin, N. and Liskova, P. and Liu, Y. and Maiga, Y. and Marignier, R. and McGuigan, C. and Meira, D. and Merle, H. and Monteiro, M.L.R. and Moodley, A. and Moura, F. and Muñoz, S. and Mustafa, S. and Nakashima, I. and Noval, S. and Oehninger, C. and Ogun, O. and Omoti, A. and Pandit, L. and Paul, F. and Rebolleda, G. and Reddel, S. and Rejdak, K. and Rejdak, R. and Rodriguez-Morales, A.J. and Rougier, M.B. and Sa, M.J. and Sanchez-Dalmau, B. and Saylor, D. and Shatriah, I. and Siva, A. and Stiebel-Kalish, H. and Szatmary, G. and Ta, L. and Tenembaum, S. and Tran, H. and Trufanov, Y. and van Pesch, V. and Wang, A.G. and Wattjes, M.P. and Willoughby, E. and Zakaria, M. and Zvornicanin, J. and Balcer, L. and Plant, G.T.
Lancet Neurology 21 (12): 1120-1134. December 2022

The role of CD4 T cells in rejection of solid tumors.
Poncette, L. and Bluhm, J. and Blankenstein, T.
Current Opinion in Immunology 74 : 18-24. February 2022

Sustainable low-field cardiovascular magnetic resonance in changing healthcare systems.
Qin, C. and Murali, S. and Lee, E. and Supramaniam, V. and Hausenloy, D.J. and Obungoloch, J. and Brecher, J. and Lin, R. and Ding, H. and Akudjedu, T.N. and Anazodo, U.C. and Jagannathan, N.R. and Ntusi, N.A.B. and Simonetti, O.P. and Campbell-Washburn, A.E. and Niendorf, T. and Mammen, R. and Adeleke, S.
European Heart Journal - Cardiovascular Imaging : jeab286. 14 February 2022

Intricacies of single-cell multi-omics data integration.
Rautenstrauch, P. and Vlot, A.H.C. and Saran, S. and Ohler, U.
Trends in Genetics 38 (2): 128-139. February 2022

Optogenetics at the presynapse.
Rost, B.R. and Wietek, J. and Yizhar, O. and Schmitz, D.
Nature Neuroscience 25 (8): 984-998. August 2022

Stroke-heart syndrome: recent advances and challenges.
Scheitz, J.F. and Sposato, L.A. and Schulz-Menger, J. and Nolte, C.H. and Backs, J. and Endres, M.
Journal of the American Heart Association 11 (17): e026528. 6 September 2022

Immunometabolic mechanisms of heart failure with preserved ejection fraction.
Schiattarella, G.G. and Alcaide, P. and Condorelli, G. and Gillette, T.G. and Heymans, S. and Jones, E.A.V. and Kallikourdis, M. and Lichtman, A. and Marelli-Berg, F. and Shah, S.J. and Thorp, E.B. and Hill, J.A.
Nature Cardiovascular Research 1 (3): 211-222. March 2022

Senescence and cancer - role and therapeutic opportunities.
Schmitt, C.A. and Wang, B. and Demaria, M.
Nature Reviews Clinical oncology 19 (10): 619–636. October 2022

Tailoring cardiac synthetic transcriptional modulation towards precision medicine.
Schoger, E. and Lelek, S. and Panáková, D. and Zelarayán, L.C.
Frontiers in Cardiovascular Medicine 8 : 783072. 14 January 2022

Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours.
Schubert, N.A. and Chen, C.Y. and Rodríguez, A. and Koster, J. and Dowless, M. and Pfister, S.M. and Shields, D.J. and Stancato, L.F. and Vassal, G. and Caron, H.N. and van den Boogaard, M.L. and Henssen, A.G. and Molenaar, J.J.
European Journal of Cancer 170 : 196-208. July 2022

Aldosteronantagonisten "revisited" [Aldosterone antagonists revisited].
Swolinsky, J. and Schmidt-Ott, K.
Nephrologe 17 : 239-245. July 2022

Microcircuits for spatial coding in the medial entorhinal cortex.
Tukker, J.J. and Beed, P. and Brecht, M. and Kempter, R. and Moser, E.I. and Schmitz, D.
Physiological Reviews 102 (2): 653-688. 1 April 2022

Effects of dietary fibers on short-chain fatty acids and gut microbiota composition in healthy adults: a systematic review.
Vinelli, V. and Biscotti, P. and Martini, D. and Del Bo', C. and Marino, M. and Meroño, T. and Nikoloudaki, O. and Calabrese, F.M. and Turroni, S. and Taverniti, V. and Unión Caballero, A. and Andrés-Lacueva, C. and Porrini, M. and Gobbetti, M. and De Angelis, M. and Brigidi, P. and Pinart, M. and Nimptsch, K. and Guglielmetti, S. and Riso, P.
Nutrients 14 (13): 2559. 1 July 2022

Precision medicine in myeloid malignancies.
Westermann, J. and Bullinger, L.
Seminars in Cancer Biology 84 : 153-169. September 2022

Application of precision medicine in clinical routine in haematology - challenges and opportunities.
Wästerlid, T. and Cavelier, L. and Haferlach, C. and Konopleva, M. and Fröhling, S. and Östling, P. and Bullinger, L. and Fioretos, T. and Smedby, K.E.
Journal of Internal Medicine 292 (2): 243-261. August 2022

Transcription factors regulating the specification of brainstem respiratory neurons.
Xia, Y. and Cui, K. and Alonso, A. and Lowenstein, E.D. and Hernandez-Miranda, L.R.
Frontiers in Molecular Neuroscience 15 : 1072475. 29 November 2022

Extrachromosomal DNA amplifications in cancer.
Yi, E. and Chamorro González, R. and Henssen, A.G. and Verhaak, R.G.W.
Nature Reviews Genetics 23 (12): 760-771. December 2022

Novel targets, treatments, and advanced models for intracerebral haemorrhage.
Zille, M. and Farr, T.D. and Keep, R.F. and Römer, C. and Xi, G. and Boltze, J.
EBioMedicine 76 : 103880. 12 February 2022

Therapeutic targets for phenolic compounds from agro-industrial by-products against obesity.
de la Luz Cádiz-Gurrea, M. and Fernández-Ochoa, Á. and Del Carmen Villegas-Aguilar, M. and Arráez-Román, D. and Segura-Carretero, A.
Current Medicinal Chemistry 29 (6): 1083-1098. 1 February 2022


A novel MAP3K20 mutation causing centronuclear myopathy-6 with fiber-type disproportion in a Pakistani family.
Ahmad, I. and Khan, A. and Noor Ul Ayan, H. and Budde, B. and Altmüller, J. and Korejo, A.A. and Nürnberg, G. and Thiele, H. and Tariq, M. and Nürnberg, P. and Erdmann, J.
Journal of Human Genetics 11 October 2022

Determinants of expression of SARS-CoV-2 entry related genes in upper and lower airways.
Aliee, H. and Massip, F. and Qi, C. and de Biase, M.S. and van Nijnatten, J. and Kersten, E.T.G. and Kermani, N.Z. and Khuder, B. and Vonk, J.M. and Vermeulen, R.C.H. and Neighbors, M. and Tew, G.W. and Grimbaldeston, M.A. and Ten Hacken, N.H.T. and Hu, S. and Guo, Y. and Zhang, X. and Sun, K. and Hiemstra, P.S. and Ponder, B.A. and Mäkelä, M.J. and Malmström, K. and Rintoul, R.C. and Reyfman, P.A. and Theis, F.J. and Brandsma, C.A. and Adcock, I.M. and Timens, W. and Xu, C.J. and van den Berge, M. and Schwarz, R.F. and Koppelman, G.H. and Nawijn, M.C. and Faiz, A.
Allergy 77 (2): 690-694. February 2022

Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M. and Dimitriou, S. and Stahler, A. and Hablesreiter, R. and Strzelecka, P.M. and Stein, C.M. and Tilgner, M. and Saiki, R. and Ogawa, S. and Bullinger, L. and Modest, D.P. and Stintzing, S. and Heinemann, V. and Damm, F.
Blood 139 (10): 1593-1597. 10 March 2022

Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity.
Batlle, D. and Monteil, V. and Garreta, E. and Hassler, L. and Wysocki, J. and Chandar, V. and Schwartz, R.E. and Mirazimi, A. and Montserrat, N. and Bader, M. and Penninger, J.M.
Cell 185 (11): 1837-1839. 26 May 2022

Up next: the dawn of systems biology in HFpEF research.
Bode, D. and Sotomayor-Flores, C. and Schiattarella, G.G.
Journal of Molecular and Cellular Cardiology 168 : 96-97. July 2022

Genotype and intensive pretreatment influence outcome of acute myeloid leukemia patients treated with venetoclax in combination with hypomethylating agents or low-dose cytarabine: "real world" data from germany.
Braitsch, K. and Schmalbrock, L.K. and Jung, P. and Bumeder, I. and Kiewe, P. and Hecker, J.S. and Verbeek, M. and Westermann, J. and Bullinger, L. and Keller, U. and Bassermann, F. and Krönke, J. and Götze, K.S. and Rieger, K.
HemaSphere 6 (9): e759. September 2022

Reply to "Interpretation of longitudinal changes of the inner nuclear layer in MS".
Cordano, C. and Yiu, H.H. and Abdelhak, A. and Beaudry-Richard, A. and Oertel, F.C. and Green, A.J.
Annals of Neurology 92 (1): 156. July 2022

Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group.
Damaschin, C. and Goergen, H. and Kreissl, S. and Plütschow, A. and Breywisch, F. and Mathas, S. and Meissner, J. and Sökler, M. and Topp, M.S. and Vucinic, V. and Zimmermann, A. and von Tresckow, B. and Fuchs, M. and Engert, A. and Borchmann, P. and Eichenauer, D.A.
Leukemia 36 (2): 580-582. February 2022

Clonal hematopoiesis of indeterminate potential-related epigenetic age acceleration correlates with clonal hematopoiesis of indeterminate potential clone size in patients with high morbidity.
Feldkamp, J.D. and Vetter, V.M. and Arends, C.M. and Lang, T.J.L. and Bullinger, L. and Damm, F. and Demuth, I. and Frick, M.
Haematologica 107 (7): 1703-1708. July 2022

Acute kidney injury in patients receiving pembrolizumab combination therapy versus pembrolizumab monotherapy for advanced lung cancer.
Gupta, S. and Strohbehn, I.A. and Wang, Q. and Hanna, P.E. and Seethapathy, R. and Prosek, J.M. and Herrmann, S.M. and Abudayyeh, A. and Malik, A.B. and Loew, S. and Carlos, C.A. and Chang, W.T. and Beckerman, P. and Mithani, Z. and Shah, C.V. and Renaghan, A. and de Seigneux, S. and Campedel, L. and Kitchlu, A. and Shin, D.S. and Coppock, G. and Lumlertgul, N. and Garcia, P. and Ortiz-Melo, D.I. and Rashidi, A. and Sprangers, B. and Aggarwal, V. and Benesova, K. and Jhaveri, K.D. and Cortazar, F.B. and Weins, A. and Zuo, Y. and Mooradian, M.J. and Reynolds, K.L. and Leaf, D.E. and Sise, M.E.
Kidney International 102 (4): 930-935. October 2022

A novel AQP2 sequence variant causing aquaporin-2 retention in the cytoplasm and autosomal dominant nephrogenic diabetes insipidus.
Hinrichs, G.R. and Baltzer, S. and Pallien, T. and Svenningsen, P. and Dalgaard, E.B. and Hertz, J.M. and Bistrup, C. and Jensen, B.L. and Klussmann, E.
Kidney International Reports 7 (10): 2289-2294. October 2022

Effect of sunitinib treatment on skin sodium accumulation in patients with renal cancer: a pilot study.
Markó, L. and Dörr, A. and Linz, P. and van den Meiracker, A.H. and Garrelds, I.M. and Kuehne, T. and Dechend, R. and Danser, A.H.J. and Flörcken, A. and Müller, D.N.
Hypertension 79 (5): e103-e105. May 2022

Standardized annotation of translated open reading frames.
Mudge, J.M. and Ruiz-Orera, J. and Prensner, J.R. and Brunet, M.A. and Calvet, F. and Jungreis, I. and Gonzalez, Jo.M. and Magrane, M. and Martinez, T.F. and Schulz, J.F. and Yang, Y.T. and Albà, M.M. and Aspden, J.L. and Baranov, P.V. and Bazzini, A.A. and Bruford, E. and Martin, M.J. and Calviello, L. and Carvunis, A.R. and Chen, J. and Couso, J.P. and Deutsch, E.W. and Flicek, P. and Frankish, A. and Gerstein, M. and Hubner, N. and Ingolia, N.T. and Kellis, M. and Menschaert, G. and Moritz, R.L. and Ohler, U. and Roucou, X. and Saghatelian, A. and Weissman, J.S. and van Heesch, S.
Nature Biotechnology 40 (7): 994–999. July 2022

Severe heart failure in the setting of inflammatory cardiomyopathy with likely pathogenic titin variant.
Mueller, M. and Zwinger, L. and Klaassen, S. and Poller, W. and Monserrat Iglesias, L. and Pablo Ochoa, J. and Klingel, K. and Landmesser, U. and Heidecker, B.
International Journal of Cardiology (IJC) Heart & Vasculature 39 : 100969. April 2022

Why angiotensin II is a poor choice for circulatory support of ventilated COVID-19 patients compared to vasopressin.
Speth, R.C. and Bader, M.
Medical Research Archives 10 (9): 3079. September 2022

Impaired AMP-activated protein kinase signaling in heart failure with preserved ejection fraction-associated atrial fibrillation.
Tong, D. and Schiattarella, G.G. and Jiang, N. and Daou, D. and Luo, Y. and Link, M.S. and Lavandero, S. and Gillette, T.G. and Hill, J.A.
Circulation 146 (1): 73-76. 5 July 2022

A peculiar case of primary central nervous system T-cell lymphoma with indolent behavior.
Wasilewski, D. and Janz, M. and Koch, A. and Rosenwald, A. and Keller, U. and Vajkoczy, P. and Faust, K. and Anagnostopoulos, I. and Radke, J.
Acta Neurologica Belgica 123 (2): 667-670. April 2022

A response to: Letter to the editor regarding "Network meta-analysis of food and drug administration-approved treatment options for adults with aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorder".
Wingerchuk, D.M. and Zhang, I. and Kielhorn, A. and Royston, M. and Levy, M. and Fujihara, K. and Nakashima, I. and Tanvir, I. and Paul, F. and Pittock, S.J.
Neurology and Therapy 2 July 2022


Blood flow meets mitophagy.
Akmeriç, E.B. and Gerhardt, H.
Journal of Cell Biology 221 (7): e202206033. 4 July 2022

In memoriam: Stephen B. McMahon, PhD, FMedSci December 21, 1954 to October 9, 2021.
Bennett, D.L.H. and Bradbury, E.J. and Lewin, G.R. and Rice, A.S.C.
Pain 163 (3): 403-405. March 2022

CEBPA mutations in AML: site matters.
Bullinger, L.
Blood 139 (1): 6-7. 6 January 2022

The blood-brain barrier-a metabolic ecosystem.
Castro, M. and Potente, M.
EMBO Journal 41 (9): e111189. 2 May 2022

SPFH protein cage - one ring to rule them all.
Daumke, O. and Lewin, G.R.
Cell Research 32 (2): 117-118. February 2022

Endothelin antagonists and the quest for a new therapeutic option in resistant hypertension.
Dechend, R. and Delles, C.
Lancet 400 (10367): 1900-1901. 3 December 2022

Shared sugars - parasite glycan homology in HIV-1 vaccine design.
Deimel, L.P. and Sattentau, Q.J.
Trends in Parasitology 38 (7): 498-500. July 2022

A deep dive into the circulating ctDNA cosmos to vanquish neuroblastoma.
Deubzer, H.E. and Astrahantseff, K. and Lodrini, M.
Cancer Discovery 12 (12): 2727-2729. 2 December 2022

A cFLIP-flop switch for senolysis.
Fan, D.N.Y. and Schmitt, C.A.
Nature Cancer 3 (11): 1279-1281. November 2022

Editorial: The long road to building a head: smooth travels and accidents on the journey from patterning via morphogenesis to phenotype.
Feistel, K. and Hammes, A. and Sela-Donenfeld, D.
Frontiers in Cell and Developmental Biology 10 : 895497. 25 April 2022

Stellenwert der kardiovaskulären Magnetresonanz in der kardiovaskulären Diagnostik [Role of cardiovascular magnetic resonance in cardiovascular diagnostics].
Gröschel, J. and Trauzeddel, R.F. and Blaszczyk, E. and Schulz-Menger, J.
Deutsche Medizinische Wochenschrift 147 (9): 528-537. 25 April 2022

Shedding light on ecDNA behavior using CRISPR-based live-cell imaging.
Henssen, A.G.
Cancer Discovery 12 (2): 293-295. 9 February 2022

Transient activated fibroblasts contribute to zebrafish heart regeneration.
Junker, J.P. and Panáková, D.
Nature Genetics 54 (8): 1076-1077. August 2022

The Case: Is this hemolytic uremic syndrome?
Kettritz, R. and Düttmann, W. and Brand, A. and Luft, F.C.
Kidney International 102 (5): 1195-1196. November 2022

Complement is complimentary in membranous nephropathy.
Kettritz, R. and Schreiber, A.
Journal of the American Society of Nephrology 33 (9): 1631-1633. September 2022

Single-cell multi-omics allows functional characterization of structural variants.
Korbel, J.O. and Sanders, A.D.
Nature Biotechnology 24 November 2022

Editorial: Sexual dimorphism in biomedical research and its therapeutic implications.
Kroon, J. and Mahmoodzadeh, S. and Helsen, C.
Frontiers in Endocrinology 13 : 1009712. 19 August 2022

Time for change in research careers: Are we as research organizations doing everything we can for postdocs?
Krull, S. and Silva, A.A. and Afanasyeva, D. and Christensen, S. and Agostinho, M.
EMBO Reports 23 (2): e54260. 3 February 2022

Editorial: Lineage tracing, hematopoietic stem cell and immune cell dynamics.
Lareau, C.A. and Romagnani, C. and Ludwig, L.S.
Frontiers in Immunology 13 : 1062415. 18 October 2022

Introducing the Molecular Pharmaceutics special issue on “tiny things, big impact: nanomedicine in Canada”.
Li, S.D. and Wasan, E. and Bally, M. and Hedtrich, S.
Molecular Pharmaceutics 19 (6): 1657-1658. 6 June 2022

Epigenetic "transgenerational" inheritance.
Luft, F.C.
Circulation 146 (14): 1096-1098. 4 October 2022

Translating plasma sodium, stores, and hydration state from mouse to man.
Luft, F.C.
European Heart Journal 43 (35): 3349-3351. 14 September 2022

Amiloride and calciuria.
Luft, F.C. and Sällström, J.
Nephrology Dialysis Transplantation 37 (2): 205-207. February 2022

ATACing single cells with phages.
Maschmeyer, P. and Haas, S.
Molecular Cell 82 (2): 234-236. 20 January 2022

Bin-based visualization of cytokine-co-expression patterns of IL-10-producing CD4 T cell subsets.
Mohr, E. and Hinnenthal, T. and Gryzik, S. and Hoang, Y. and Lischke, T. and Retzlaff, J. and Mekonnen, A. and Paul, F. and Valleriani, A. and Radbruch, A. and Vera, J. and Baumgrass, R.
European Journal of Immunology 52 (10): 1684-1687. October 2022

Sizing up beta cells made from stem cells.
Nguyen-Ngoc, K.V. and Wortham, M. and Sander, M.
Nature Biotechnology 40 (7): 1006-1008. July 2022

Cellular hierarchies predict drug response in acute myeloid leukemia.
Raffel, S. and Velten, L. and Haas, S.
Cancer Cell 40 (9): 917-919. 12 September 2022

Dissecting the intracellular pancreatic tumor microbiome at single-cell level.
Schmidt, T.S.B. and Bork, P.
Cancer Cell 40 (10): 1083-1085. 10 October 2022

COVID-19: new disease mechanism is simultaneously a therapeutic target.
Schmitt, C.A.
memo: Magazine of European Medical Oncology 15 (2): 100-101. June 2022

Editorial: Mitochondria as a hub in cellular signaling.
Stoolman, J.S. and Porcelli, A.M. and Martínez-Reyes, I.
Frontiers in Cell and Developmental Biology 10 : 981464. 15 August 2022

Cancer stem cells: The adventurous journey from hematopoietic to leukemic stem cells.
Trumpp, A. and Haas, S.
Cell 185 (8): 1266-1270. 14 April 2022

Time-keeping and decision-making in living cells: Part II.
Tyson, J.J. and Csikasz-Nagy, A. and Gonze, D. and Kim, J.K. and Santos, S. and Wolf, J.
Interface Focus 12 (4): 20220024. 10 June 2022

Time-keeping and decision-making in living cells: Part I.
Tyson, J.J. and Csikasz-Nagy, A. and Gonze, D. and Kim, J.K. and Santos, S. and Wolf, J.
Interface Focus 12 (3): 20220011. 6 June 2022

Interneuron switching on and off across memory rhythms.
Tzilivaki, A. and Maier, N. and Schmitz, D.
Neuron 110 (12): 1884-1886. 15 June 2022


Taking out the trash: How misfolded proteins are removed from the endoplasmic reticulum.
Brodsky, J.L. and Engelman, D.M. and Hendershot, L.M. and Piana-Agostinetti, S. and Sommer, T.
Faculty Reviews 11 : 29. 5 October 2022


Expanding the Huntington’s disease research toolbox; validated subdomain protein constructs for biochemical and structural investigation of huntingtin.
Alteen, M.G. and Deme, J.C. and Alvarez, C.P. and Loppnau, P. and Hutchinson, A. and Seitova, A. and Chandrasekaran, R. and Silva Ramos, E. and Secker, C. and Alqazzaz, M. and Wanker, E.E. and Lea, S.M. and Arrowsmith, C.H. and Harding, R.J.
bioRxiv : 2022.11.21.516512. 22 November 2022

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M. and Grishkovskaya, I. and Benedum, J. and Franke, V. and Polyansky, A. and Neudolt, A. and Wunder, A. and Zagrovic, B. and Akalin, A. and Djinovic-Carugo, K. and Slade, D.
bioRxiv : 2022.02.26.482114. 27 February 2022

PyZebraScope: an open-source platform for brain-wide neural activity imaging in zebrafish.
Barbara, R. and Nagathihalli Kantharaju, M. and Haruvi, R. and Harrington, K. and Kawashima, T.
bioRxiv : bioRxiv. 15 February 2022

Synapsin autoantibodies during pregnancy are associated with fetal abnormalities.
Bünger, I. and Kreye, J. and Makridis, K. and Höltje, M. and Rasmussen, H.F. and Van Hoof, S. and Ullrich, T. and Sedlin, E. and Hoffmann, C. and Milovanovic, D. and Paul, F. and Meckies, J. and Verlohren, S. and Henrich, W. and Chaoui, R. and Kaindl, A. and Prüss, H.
medRxiv : 2022.09.23.22280284. 25 September 2022

Global analysis of human-to-mouse contact-dependent intercellular mRNA and lncRNA transfer in cell culture.
Dasgupta, Sandipan and Dyagi, Daniella Y. and Haimovich, Gal and Wyler, E. and Olender, Tsviya and Singer, Robert H. and Landthaler, M. and Gerst, Jeffrey E
bioRxiv : 2021.11.28.470233v2. 7 March 2022

Anti-SARS-CoV-2 antibody containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19 via increased neutralizing antibody activity – a randomized clinical trial.
Denkinger, C.M. and Janssen, M. and Schäkel, U. and Gall, J. and Leo, A. and Stelmach, P. and Weber, S.F. and Krisam, J. and Baumann, L. and Stermann, J. and Merle, U. and Weigand, M.A. and Nusshag, C. and Bullinger, L. and Schrezenmeier, J.F. and Bornhäuser, M. and Alakel, N. and Witzke, O. and Wolf, T. and Vehreschild, M.J.G.T. and Schmiedel, S. and Addo, M.M. and Herth, F. and Kreuter, M. and Tepasse, P.R. and Hertenstein, B. and Hänel, M. and Morgner, A. and Kiehl, M. and Hopfer, O. and Wattad, M.A. and Schimanski, C.C. and Celik, C. and Pohle, T. and Ruhe, M. and Kern, W.V. and Schmitt, A. and Lorenz, H.M. and Souto-Carneiro, M. and Gaeddert, M. and Halama, N. and Meuer, S. and Kräusslich, H.G. and Müller, B. and Schnitzler, P. and Parthé, S. and Bartenschlager, R. and Gronkowski, M. and Klemmer, J. and Schmitt, M. and Dreger, P. and Kriegsmann, K. and Schlenk, R.F. and Müller-Tidow, C.
medRxiv : 2022.10.10.22280850. 13 October 2022

The lncRNA landscape of cardiac resident macrophages and identification of Schlafenlnc as a regulator of macrophage migratory function.
Dueck, A. and Althaus, L. and Heise, K. and Esfandyari, D. and Bayguen, S. and Brandes, R.P. and Gagneur, J. and Jae, N. and Knolle, P. and Leisegang, M.S. and Maegdefessel, L. and Meitinger, T. and Petzold, N. and Ramanujam, D. and Sager, H. and Schulz, C. and Theodorakis, E. and Uzonyi, A. and Weinberger, T. and Bader, M. and Schmidt-Supprian, M. and Engelhardt, S.
bioRxiv : 2022.11.30.518576. 22 December 2022

Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in severe COVID-19.
Essex, M. and Pascual-Leone, B.M. and Löber, U. and Kuhring, M. and Zhang, B. and Bruening, U. and Fritsche-Guenther, R. and Krzanowski, M. and Vernengo, F.F. and Brumhard, S. and Röwekamp, I. and Bielecka, A.A. and Lesker, T.R. and Wyler, E. and Landthaler, M. and Mantei, A. and Meisel, C. and Caesar, S. and Thiebeault, C. and Corman, V. and Marko, L. and Suttorp, N. and Strowig, T. and Kurth, F. and Sander, L.E. and Li, Y. and Kirwan, J.A. and Forslund, S.K. and Opitz, B.
bioRxiv : 2022.12.02.518860. 2 December 2022

One gene - two proteins: the C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria.
Fasciani, I. and Petragnano, F. and Wang, Z. and Edwards, R. and Telugu, N. and Pietrantoni, I. and Zauber, H. and Rossi, M. and Zabel, U. and Grieben, M. and Terzenidou, M.E. and Di Gregorio, J. and Pellegrini, C. and Santini, S. and Taddei, A.R. and Poehl, B. and Aringhieri, S. and Aloisi, G. and Marampon, F. and Roman, A. and Diecke, S. and Flati, V. and Giorgi, F. and Amicarelli, F. and Tobin, A.B. and Scarselli, M. and Tokatlidis, K. and Lohse, M.J. and Maggio, R. and Annibale, P.
bioRxiv : 2021.04.13.438299. 26 February 2022

C. difficile is overdiagnosed in adults and a commensal in infants.
Ferretti, P. and Wirbel, J. and Maistrenko, O.M. and Van Rossum, T. and Alves, R. and Fullam, A. and Akanni, W. and Schudoma, C. and Schwarz, A. and Thielemann, R. and Thomas, L. and Kuhn, M. and Zeller, G. and Schmidt, T.S.B. and Bork, P.
bioRxiv : 2022.02.16.480740v1. 18 February 2022

Branch point evolution controls species-specific alternative splicing and regulates long term potentiation.
Franz, A. and Weber, A.I. and Preußner, M. and Dimos, N. and Stumpf, A. and Ji, Y. and Moreno-Velasquez, L. and Voigt, A. and Schulz, F. and Neumann, A. and Kuropka, B. and Kühn, R. and Urlaub, H. and Schmitz, D. and Wahl, M.C. and Heyd, F.
bioRxiv : 2022.09.09.507289. 11 September 2022

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development.
Freitag, K. and Eede, P. and Ivanov, A. and Schneeberger, S. and Borodina, T. and Sauer, S. and Beule, D. and Heppner, F.
Research Square : rs.3.rs-1362379/v1. 28 February 2022

Modeling IP(3) induced Ca(2+) signaling based on its interspike interval statistics.
Friedhoff, V.N. and Falcke, M.
bioRxiv : 2022.12.20.521161. 20 December 2022

Regulation of prostate androgens by megalin and 25-hydroxyvitamin D status: Mechanism for high prostate androgen in African American men.
Garcia, J. and Krieger, K. and Loitz, C. and Perez, L.M. and Richards, Z.A. and Helou, Y.B. and Kregel, S. and Selada, S. and Mesaros, C.A. and Gann, P. and Willnow, T.E. and Vander Griend, D. and Kittles, R. and Prins, G. and Penning, T. and Nonn, L.
bioRxiv : 2021.11.09.467567v5. 1 September 2022

Epstein-Barr virus-driven B cell lymphoma mediated by a unique LMP1-TRAF6 complex.
Giehler, F. and Ostertag, M. and Sommermann, T. and Weidl, D. and Sterz, K. and Kutz, H. and Feller, S. and Geerlof, A. and Biesinger, B. and Popowicz, G. and Kirchmair, J. and Kieser, A.
Research Square : rs.3.rs-1295699/v1. 4 February 2022

Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia.
Gilioli, D. and Fusco, S. and Tavella, T. and Giannetti, K. and Conti, A. and Santoro, A. and Carsana, E. and Beretta, S. and Schönlein, M. and Gambacorta, V. and Aletti, F.M. and Carraba, M.G. and Bonini, C. and Ciceri, F. and Merelli, I. and Vago, L. and Schmitt, C.A. and Di Micco, R.
bioRxiv : 2022.11.17.515658. 17 November 2022

Aging-regulated TUG1 is dispensable for endothelial cell function.
Gimbel, A.T. and Koziarek, S. and Theodorou, K. and Schulz, J.F. and Stanicek, L. and Ali, T. and Günther, S. and Kumar, S. and Jo, H. and Hübner, N. and Maegdefessel, L. and Dimmeler, S. and van Heesch, S. and Boon, R.A.
bioRxiv : 2022.02.27.482212. 28 February 2022

Beta cell dysfunction and dedifferentiation induced by Bone Morphogenetic Protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.
Ibarra, A. and Prause, M. and Ingerslev, L. and Wortham, M. and Sui, Y. and Sander, M. and Williams, K. and Barrès, R. and Larsen, M. and Christensen, G. and Billestrup, N.
Research Square : rs-2254065. 23 November 2022

Monitoring mitochondrial translation by pulse SILAC.
Imami, K. and Selbach, M. and Ishihama, Y.
bioRxiv : 2021.01.31.428997. 8 June 2022

Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Keil, P. and Wulf, A. and Kachariya, N. and Reuscher, S. and Hühn, K. and Silbern, I. and Altmüller, J. and Stehle, R. and Zarnack, K. and Sattler, M. and Urlaub, H. and Sträßer, K.
bioRxiv : 2022.07.22.501171. 22 July 2022

Proteolytic cleavage of the extracellular domain affects signaling of parathyroid hormone receptor 1.
Klenk, C. and Hommers, L. and Lohse, M.J.
bioRxiv : 2021.12.16.472984. 19 January 2022

Spatio-temporal, optogenetic control of gene expression in organoids.
Legnini, I. and Emmenegger, L. and Zappulo, A. and Wurmus, R. and Oliveras Martinez, A. and Cerda Jara, C. and Boltengagen, A. and Hessler, T. and Mastrobuoni, G. and Rybak-Wolf, A. and Kempa, S. and Zinzen, R.P. and Woehler, A. and Rajewsky, N.
bioRxiv : 2021.09.26.461850v3. 9 February 2022

A weak-labelling and deep learning approach for in-focus object segmentation in 3D widefield microscopy.
Li, R. and Kudryashev, M. and Yakimovich, A.
Research Square : rs.3.rs-2362531/v1. 20 December 2022

The little skate genome and the evolutionary emergence of wing-like fin appendages.
Marletaz, F. and de la Calle-Mustienes, E. and Acemel, R.D. and Nakamura, T. and Paliou, C. and Naranjo, S. and Martinez-Garcia, P.M. and Cases, I. and Sleight, V.A. and Hirschberger, C. and Marcet-Houben, M. and Navon, D. and Andrescavage, A. and Skvortsova, K. and Duckett, P.E. and Gonzalez-Rajal, A. and Bogdanovic, O. and Gibcus, J.H. and Yang, L. and Gallardo-Fuentes, L. and Sospedra, I. and Lopez-Rios, J. and Darbellay, F. and Visel, A. and Dekker, J. and Shubin, N. and Gabaldon, T. and Tena, J.J. and Lupianez, D.G. and Rokhsar, D.S. and Gomez-Skarmeta, J.L.
bioRxiv : 2022.03.21.485123. 22 March 2022

Despite the odds: formation of the SARS-CoV-2 methylation complex.
Matsuda, A. and Plewka, J. and Chykunova, Y. and Jones, A.N. and Pachota, M. and Rawski, M. and Mourão, A. and Karim, A. and Kresik, L. and Lis, K. and Minia, I. and Hartman, K. and Sonani, R. and Schlauderer, F. and Dubin, G. and Sattler, M. and Suder, P. and Popowicz, G. and Pyrć, K. and Czarna, A.
bioRxiv : 2022.01.25.477673. 1 March 2022

Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.
Monti, R. and Rautenstrauch, P. and Ghanbari, M. and James, A.R. and Ohler, U. and Konigorski, S. and Lippert, C.
bioRxiv : 2021.05.27.444972. 20 January 2022

The molecular mechanism and physiological role of silent nociceptor activation.
Nees, T.A. and Wang, N. and Adamek, P. and Verkest, C. and Schaefer, I. and Virnich, J. and Balkaya, S. and Prato, V. and Morelli, C. and Zeitzschel, N. and Begay, V. and Lee, Y.J. and Lewin, G.R. and Heppenstall, P.A. and Taberner, F.J. and Lechner, S.G.
bioRxiv : 2022.04.07.486730. 19 October 2022

The rate of spontaneous mutations in yeast deficient for MutSβ function.
Plavskin, Y. and de Biase, M.S. and Schwarz, R.F. and Siegal, M.L.
bioRxiv : 2022.08.25.505291v2. 26 November 2022

Long-term imaging reveals behavioral plasticity during C. elegans dauer exit.
Preusser, F. and Neuschulz, A. and Junker, J.P. and Rajewsky, N. and Preibisch, S.
bioRxiv : 2022.04.25.489360v1. 26 April 2022

Liam tackles complex multimodal single-cell data integration challenges.
Rautenstrauch, P. and Ohler, U.
bioRxiv : 2022.12.21.521399. 22 December 2022

Functional and evolutionary significance of unknown genes from uncultivated taxa.
Rodríguez del Río, Á. and Giner-Lamia, J. and Cantalapiedra, C.P. and Botas, J. and Deng, Z. and Hernández-Plaza, A. and Paoli, L. and Schmidt, T.S.B. and Sunagawa, S. and Bork, P. and Coelho, L.P. and Huerta-Cepas, J.
bioRxiv : 10.1101/2022.01.26.477801. 27 January 2022

Panoptic segmentation with highly imbalanced semantic labels.
Rumberger, J.L. and Baumann, E. and Hirsch, P. and Janowczyk, A. and Zlobec, I. and Kainmueller, D.
arXiv : 2203.11692. 19 April 2022

Similar neural pathways link psychological stress and brain health in health and multiple sclerosis.
Schulz, M.A. and Hetzer, S. and Eitel, F. and Asseyer, S. and Meyer-Arndt, L. and Schmitz-Hübsch, T. and Bellmann-Strobl, J. and Cole, J.H. and Gold, S.M. and Paul, F. and Ritter, K. and Weygandt, M.
bioRxiv : 2022.12.19.521098. 20 December 2022

A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ cells to diabetes recovery in zebrafish.
Singh, S.P. and Chawla, P. and Hnatiuk, A. and Kamel, M. and Silva, L.D. and Spanjard, B. and Eski, S.E. and Janjuha, S. and Olivares, P. and Kayisoglu, O. and Rost, F. and Bläsche, J. and Kränkel, A. and Petzold, A. and Kurth, T. and Reinhardt, S. and Junker, J.P. and Ninov, N.
bioRxiv : 2021.06.24.449704. 31 January 2022

SMITH: spatially constrained stochastic model for simulation of intra-tumour heterogeneity.
Streck, A. and Kaufmann, T. and Schwarz, R.F.
bioRxiv : 2022.07.22.501136. 24 July 2022

Coordinated cadherin functions sculpt respiratory motor circuit connectivity.
Vagnozzi, A.N. and Moore, M.T. and Lin, M. and Brozost, E.M. and KC, R. and Agarwal, A. and Schwarz, L.A. and Duan, X. and Zampieri, N. and Landmesser, L.T. and Philippidou, P.
bioRxiv : 2022.08.02.502511. 4 August 2022

Differential ripple propagation along the hippocampal longitudinal axis.
de Filippo, R. and Schmitz, D.
bioRxiv : 2022.12.22.521603. 22 December 2022

This list was generated on Fri May 24 02:12:16 2024 CEST.
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