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Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.
Abdelhak, A., Cordano, C., Boscardin, W.J., Caverzasi, E., Kuhle, J., Chan, B., Gelfand, J.M., Yiu, H.H., Oertel, F.C., Beaudry-Richard, A., Condor Montes, S., Oksenberg, J.R., Lario Lago, A., Boxer, A., Rojas-Martinez, J.C., Elahi, F.M., Chan, J.R. and Green, A.J.
Journal of Neurology Neurosurgery and Psychiatry 93
(9): 972-977.
12 August 2022
Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.
Abdelhak, A., Solomon, I., Montes, S.C., Saias, A., Cordano, C., Asken, B., Fonseca, C., Oertel, F.C., Arfanakis, K., Staffaroni, A.M., Kramer, J.H., Geschwind, M., Miller, B.L., Elahi, F.M. and Green, A.J.
Alzheimer's & Dementia: Diagnosis Assessment & Disease Monitoring 14
(1): e12338.
2022
HDHL-INTIMIC: a European knowledge platform on food, diet, intestinal microbiomics, and human health.
Agamennone, V., Abuja, P.M., Basic, M., De Angelis, M., Gessner, A., Keijser, B., Larsen, M., Pinart, M., Nimptsch, K., Pujos-Guillot, E., Schlicht, K., Sharon, I., Untersmayr, E., Laudes, M., Pischon, T. and Bouwman, J.
Nutrients 14
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29 April 2022
A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4(+) T cells and is defective in Crohn's disease patients.
Ahlers, J., Mantei, A., Lozza, L., Stäber, M., Heinrich, F., Bacher, P., Hohnstein, T., Menzel, L., Yüz, S.G., Alvarez-Simon, D., Bickenbach, A.R., Weidinger, C., Mockel-Tenbrinck, N., Kühl, A.A., Siegmund, B., Maul, J., Neumann, C. and Scheffold, A.
Mucosal Immunology 15
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May 2022
A novel MAP3K20 mutation causing centronuclear myopathy-6 with fiber-type disproportion in a Pakistani family.
Ahmad, I., Khan, A., Noor Ul Ayan, H., Budde, B., Altmüller, J., Korejo, A.A., Nürnberg, G., Thiele, H., Tariq, M., Nürnberg, P. and Erdmann, J.
Journal of Human Genetics
11 October 2022
Blood flow meets mitophagy.
Akmeriç, E.B. and Gerhardt, H.
Journal of Cell Biology 221
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4 July 2022
Midwall fibrosis and cardiac mechanics: rigid body rotation is a novel marker of disease severity in pediatric primary dilated cardiomyopathy.
Al-Wakeel-Marquard, N., Seidel, F., Kühnisch, J., Kuehne, T., Berger, F., Messroghli, D.R. and Klaassen, S.
Frontiers in Cardiovascular Medicine 8
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17 February 2022
Angiotensin 1-7 increases fiber cross sectional area and force in juvenile mouse skeletal muscle.
Albadrani, H., Ammar, T., Rajgara, R., Bader, M., Wiper-Bergeron, N. and Renaud, J.M.
American Journal of Physiology Cell Physiology 323
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December 2022
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H., Flórez, A.F., Kreth, S., Brückner, L.M., Yildiz, U., Gartlgruber, M., Odoni, D.I., Poschet, G., Garbowicz, K., Shao, C., Klein, C., Meier, J., Zeisberger, P., Nadler-Holly, M., Ziehm, M., Paul, F., Burhenne, J., Bell, E., Shaikhkarami, M., Würth, R., Stainczyk, S.A., Wecht, E.M., Kreth, J., Büttner, M., Ishaque, N., Schlesner, M., Nicke, B., Stresemann, C., Llamazares-Prada, M., Reiling, J.H., Fischer, M., Amit, I., Selbach, M., Herrmann, C., Wölfl, S., Henrich, K.O., Höfer, T., Trumpp, A. and Westermann, F.
Nature Cancer 3
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28 April 2022
Single cell metabolism: current and future trends.
Ali, A., Davidson, S., Fraenkel, E., Gilmore, I., Hankemeier, T., Kirwan, J.A., Lane, A.N., Lanekoff, I., Larion, M., McCall, L.I., Murphy, M., Sweedler, J.V. and Zhu, C.
Metabolomics 18
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1 October 2022
Determinants of expression of SARS-CoV-2 entry related genes in upper and lower airways.
Aliee, H., Massip, F., Qi, C., de Biase, M.S., van Nijnatten, J., Kersten, E.T.G., Kermani, N.Z., Khuder, B., Vonk, J.M., Vermeulen, R.C.H., Neighbors, M., Tew, G.W., Grimbaldeston, M.A., Ten Hacken, N.H.T., Hu, S., Guo, Y., Zhang, X., Sun, K., Hiemstra, P.S., Ponder, B.A., Mäkelä, M.J., Malmström, K., Rintoul, R.C., Reyfman, P.A., Theis, F.J., Brandsma, C.A., Adcock, I.M., Timens, W., Xu, C.J., van den Berge, M., Schwarz, R.F., Koppelman, G.H., Nawijn, M.C. and Faiz, A.
Allergy 77
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February 2022
Age-related mechanisms in the context of rheumatic disease.
Alsaleh, G., Richter, F.C. and Simon, A.K.
Nature Reviews Rheumatology 18
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December 2022
Lifting the veil of secrecy: maternal and neonatal outcome of oocyte donation pregnancies in Germany.
Altmann, J., Kummer, J., Herse, F., Hellmeyer, L., Schlembach, D., Henrich, W. and Weichert, A.
Archives of Gynecology and Obstetrics 306
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July 2022
The monocyte, a maestro in the tumor microenvironment (TME) of breast cancer.
Amer, H.T., Stein, U. and El Tayebi, H.M.
Cancers 14
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7 November 2022
Acute myocarditis associated with desmosomal gene variants.
Ammirati, E., Raimondi, F., Piriou, N., Sardo Infirri, L., Mohiddin, S.A., Mazzanti, A., Shenoy, C., Cavallari, U.A., Imazio, M., Aquaro, G.D., Olivotto, I., Pedrotti, P., Sekhri, N., Van de Heyning, C.M., Broeckx, G., Peretto, G., Guttmann, O., Dellegrottaglie, S., Scatteia, A., Gentile, P., Merlo, M., Goldberg, R.I., Reyentovich, A., Sciamanna, C., Klaassen, S., Poller, W., Trankle, C.R., Abbate, A., Keren, A., Horowitz-Cederboim, S., Cadrin-Tourigny, J., Tadros, R., Annoni, G.A., Bonoldi, E., Toquet, C., Marteau, L., Probst, V., Trochu, J.N., Kissopoulou, A., Grosu, A., Kukavica, D., Trancuccio, A., Gil, C., Tini, G., Pedrazzini, M., Torchio, M., Sinagra, G., Gimeno, J.R., Bernasconi, D., Valsecchi, M.G., Klingel, K., Adler, E.D., Camici, P.G. and Cooper, L.T.
JACC Heart Fail 10
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October 2022
In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.
Anania, C., Acemel, R.D., Jedamzick, J., Bolondi, A., Cova, G., Brieske, N., Kühn, R., Wittler, L., Real, F.M. and Lupiáñez, D.G.
Nature Genetics
July 2022
Different impact of gadopentetate and gadobutrol on inflammation-promoted retention and toxicity of gadolinium within the mouse brain.
Anderhalten, L., Silva, R.V., Morr, A., Wang, S., Smorodchenko, A., Saatz, J., Traub, H., Mueller, S., Boehm-Sturm, P., Rodriguez-Sillke, Y., Kunkel, D., Hahndorf, J., Paul, F., Taupitz, M., Sack, I. and Infante-Duarte, C.
Investigative Radiology 57
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1 October 2022
The role of respiratory microbiota in the protection against viral diseases: respiratory commensal bacteria as next-generation probiotics for COVID-19.
Andrade, B.G.N., Cuadrat, R.R.C., Tonetti, F.R., Kitazawa, H. and Villena, J.
Bioscience of Microbiota, Food and Health 41
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1 July 2022
De novo whole genome assembly of the Roborovski dwarf hamster (Phodopus roborovskii) genome, an animal model for severe/critical COVID-19.
Andreotti, S., Altmüller, J., Quedenau, C., Borodina, T., Nouailles, G., Teixeira Alves, L.G., Landthaler, M., Bieniara, M., Trimpert, J. and Wyler, E.
Genome Biology and Evolution 14
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July 2022
Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming.
Anh, L.P.H., Nishimura, K., Kuno, A., Nguyen, T.L., Kato, T., Ohtaka, M., Nakanishi, M., Sugihara, E., Sato, T.A., Hayashi, Y., Fukuda, A. and Hisatake, K.
Stem Cells 40
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29 April 2022
Integrative analysis of macrophage ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classes.
Ansari, S.A., Dantoft, W., Ruiz-Orera, J., Syed, A.P., Blachut, S., van Heesch, S., Hübner, N. and Uhlenhaut, N.H.
Computational and Structural Biotechnology Journal 20
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3 October 2022
Prognostic value of stress cardiac magnetic resonance in patients with known coronary artery disease.
Antiochos, P., Ge, Y., Heydari, B., Steel, K., Bingham, S., Abdullah, S.M., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 15
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January 2022
Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling.
Anton, S.E., Kayser, C., Maiellaro, I., Nemec, K., Möller, J., Koschinski, A., Zaccolo, M., Annibale, P., Falcke, M., Lohse, M.J. and Bock, A.
Cell 185
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31 March 2022
Carbon-mixed dental cement for fixing fiber optic ferrules prevents visually triggered locomotive enhancement in mice upon optogenetic stimulation.
Araragi, N., Alenina, N. and Bader, M.
Heliyon 8
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January 2022
Clonal hematopoiesis is associated with improved survival in patients with metastatic colorectal cancer from the FIRE-3 trial.
Arends, C.M., Dimitriou, S., Stahler, A., Hablesreiter, R., Strzelecka, P.M., Stein, C.M., Tilgner, M., Saiki, R., Ogawa, S., Bullinger, L., Modest, D.P., Stintzing, S., Heinemann, V. and Damm, F.
Blood 139
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10 March 2022
Management of malignant dysgerminoma of the ovary.
Arndt, T., Taube, E.T., Deubzer, H.E., Rothe, K., Calaminus, G., Sehouli, J. and Pietzner, K.
European Journal of Gynaecological Oncology 43
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15 April 2022
Immunohistochemical analysis of nicotinamide phosphoribosyltransferase expression in gastric and esophageal adenocarcinoma (AEG).
Arnold, A., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Krenzien, F., Stein, U. and Treese, C.
Gastrointestinal Disorders 4
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13 December 2022
Kinin B1 receptor modulates mitochondrial activity responsivity in fasting and voluntary exercise.
Arruda, A.C., Budu, A., de Menezes, T.N., Bader, M., Araujo, R.C. and Freitas-Lima, L.C.
Life Sciences 309
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15 November 2022
LABKIT: labeling and segmentation toolkit for big image data.
Arzt, M., Deschamps, J., Schmied, C., Pietzsch, T., Schmidt, D., Tomancak, P., Haase, R. and Jug, F.
Frontiers in Computer Science 4
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10 February 2022
De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway.
Asif, M., Kaygusuz, E., Shinawi, M., Nickelsen, A., Hsieh, T.C., Wagle, P., Budde, B., Hochscherf, J., Abdullah, U., Höning, S., Nienberg, C., Lindenblatt, D., Noegel, A.A., Altmüller, J., Thiele, H., Motameny, S., Fleischer, N., Segal, I., Pais, L., Tinschert, S., Samra, N.G., Savatt, J.M., Rudy, N.L., De Luca, C., Fortugno, P., White, S.M., Krawitz, P., Hurst, A.C.E., Niefind, K., Jose, J., Brancati, F., Nürnberg, P. and Hussain, M.S.
Human Genetics and Genomics Advances 3
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14 July 2022
A novel missense variant of SCN4A co-segregates with congenital essential tremor in a consanguineous Kurdish family.
Asif, M., Mocanu, I.D., Abdullah, U., Höhne, W., Altmüller, J., Makhdoom, E.U.H., Thiele, H., Baig, S.M., Nürnberg, P., Graul-Neumann, L. and Hussain, M.S.
American Journal of Medical Genetics A 188
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April 2022
Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
Axelsson Raja, A., Wakimoto, H., DeLaughter, D.M., Reichart, D., Gorham, J., Conner, D.A., Lun, M., Probst, C.K., Sakai, N., Knipe, R.S., Montesi, S.B., Shea, B., Adam, L.P., Leinwand, L.A., Wan, W., Choi, E.S., Lindberg, E.L., Patone, G., Noseda, M., Hübner, N., Seidman, C.E., Tager, A.M., Seidman, J.G. and Ho, C.Y.
Proceedings of the National Academy of Sciences of the United States of America 119
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12 July 2022
Impaired motion perception is associated with functional and structural visual pathway damage in multiple sclerosis and neuromyelitis optica spectrum disorders.
Ayadi, N., Oertel, F.C., Asseyer, S., Rust, R., Duchow, A., Kuchling, J., Bellmann-Strobl, J., Ruprecht, K., Klistorner, A., Brandt, A.U., Paul, F. and Zimmermann, H.G.
Multiple Sclerosis Journal 28
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April 2022
Selective endocytosis of Ca(2+)-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.
Azarnia Tehran, D., Kochlamazashvili, G., Pampaloni, N. P., Sposini, S., Shergill, J.K., Lehmann, M., Pashkova, N., Schmidt, C., Löwe, D., Napieczynska, H., Heuser, A., Plested, A.J.R., Perrais, D., Piper, R.C., Haucke, V. and Maritzen, T.
Science Advances 8
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27 May 2022
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A naked eye-invisible ratiometric fluorescent microneedle tattoo for real-time monitoring of inflammatory skin conditions.
Babity, S., Couture, F., Campos, E.V.R., Hedtrich, S., Hagen, R., Fehr, D., Bonmarin, M. and Brambilla, D.
Advanced Healthcare Materials 11
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March 2022
Anatomical and functional visual network patterns in progressive multiple sclerosis.
Backner, Y., Zamir, S., Petrou, P., Paul, F., Karussis, D. and Levin, N.
Human Brain Mapping 43
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1 April 2022
RS-FISH: precise, interactive, fast, and scalable FISH spot detection.
Bahry, E., Breimann, L., Zouinkhi, M., Epstein, L., Kolyvanov, K., Mamrak, N., King, B., Long, Xi, Harrington, K.I.S., Lionnet, T. and Preibisch, S.
Nature Methods 19
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December 2022
Microglia form satellites with different neuronal subtypes in the adult murine central nervous system.
Bakina, O., Kettenmann, H. and Nolte, C.
Journal of Neuroscience Research 100
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April 2022
Unraveling the hidden temporal range of fast β(2)-adrenergic receptor mobility by time-resolved fluorescence.
Balakrishnan, A., Hemmen, K., Choudhury, S., Krohn, J.H., Jansen, K., Friedrich, M., Beliu, G., Sauer, M., Lohse, M.J. and Heinze, K.G.
Communications Biology 5
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28 February 2022
Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S., Andreani, M., Goncalves Andrade, J., Saha, T., Sundaravinayagam, D., Garzón, J., Zhang, W., Popp, O., Hiraga, S., Rahjouei, A., Rosen, D.B., Mertins, P., Chait, B.T., Donaldson, A.D. and Di Virgilio, M.
eLife 11
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13 April 2022
Aurora kinase A is involved in controlling the localization of aquaporin-2 in renal principal cells.
Baltzer, S., Bulatov, T., Schmied, C., Krämer, A., Berger, B.T., Oder, A., Walker-Gray, R., Kuschke, C., Zühlke, K., Eichhorst, J., Lehmann, M., Knapp, S., Weston, J., von Kries, J.P., Süssmuth, R.D. and Klussmann, E.
International Journal of Molecular Sciences 23
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11 January 2022
Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements.
Baranasic, D., Hörtenhuber, M., Balwierz, P.J., Zehnder, T., Mukarram, A.K., Nepal, C., Várnai, C., Hadzhiev, Y., Jimenez-Gonzalez, A., Li, N., Wragg, J., D'Orazio, F.M., Relic, D., Pachkov, M., Díaz, N., Hernández-Rodríguez, B., Chen, Z., Stoiber, M., Dong, M., Stevens, I., Ross, S.E., Eagle, A., Martin, R., Obasaju, O., Rastegar, S., McGarvey, A.C., Kopp, W., Chambers, E., Wang, D., Kim, H.R., Acemel, R.D., Naranjo, S., Łapiński, M., Chong, V., Mathavan, S., Peers, B., Sauka-Spengler, T., Vingron, M., Carninci, P., Ohler, U., Lacadie, S.A., Burgess, S.M., Winata, C., van Eeden, F., Vaquerizas, J.M., Gómez-Skarmeta, J.L., Onichtchouk, D., Brown, B.J., Bogdanovic, O., van Nimwegen, E., Westerfield, M., Wardle, F.C, Daub, C.O., Lenhard, B. and Müller, F.
Nature Genetics 54
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July 2022
Multi-omics alleviates the limitations of panel sequencing for cancer drug response prediction.
Baranovskii, A., Gündüz, I.B., Franke, V., Uyar, B. and Akalin, A.
Cancers 14
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15 November 2022
Transcriptome analysis reveals high tumor heterogeneity with respect to re-activation of stemness and proliferation programs.
Baranovsky, A., Ivanov, T., Granovskaya, M., Papatsenko, D. and Pervouchine, D.D.
PLoS ONE 17
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19 May 2022
PyZebraScope: an open-source platform for brain-wide neural activity imaging in zebrafish.
Barbara, R., Nagathihalli Kantharaju, M., Haruvi, R., Harrington, K. and Kawashima, T.
Frontiers in Cell and Developmental Biology 10
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19 May 2022
Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A., Malhan, D., Dumbani, M., Dahlmann, M., Stein, U. and Relógio, A.
Cancers 14
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16 July 2022
Role of endothelial kinin B(1) receptor on the membrane potential of transgenic rat aorta.
Batista, C., Sales, V.M., Merino, V.F., Bader, M., Feres, T. and Pesquero, J.B.
Physiological Research 71
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August 2022
Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity.
Batlle, D., Monteil, V., Garreta, E., Hassler, L., Wysocki, J., Chandar, V., Schwartz, R.E., Mirazimi, A., Montserrat, N., Bader, M. and Penninger, J.M.
Cell 185
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26 May 2022
Sexual dimorphism in extracellular matrix composition and viscoelasticity of the healthy and inflamed mouse brain.
Batzdorf, C.S., Morr, A.S., Bertalan, G., Sack, I., Silva, R.V. and Infante-Duarte, C.
Biology 11
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31 January 2022
State-of-the-art analytical methods of viral infections in human lung organoids.
Baumgardt, M., Hülsemann, M., Löwa, A., Fatykhova, D., Hoffmann, K., Kessler, M., Mieth, M., Hellwig, K., Frey, D., Langenhagen, A., Voss, A., Obermayer, B., Wyler, E., Dökel, S., Gruber, A.D., Tölch, U., Hippenstiel, S., Hocke, A.C. and Hönzke, K.
PLoS ONE 17
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20 December 2022
Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics.
Bayram, S., Razzaque, Y.S., Geisberger, S., Pietzke, M., Fürst, S., Vechiatto, C., Forbes, M., Mastrobuoni, G. and Kempa, S.
Frontiers in Molecular Biosciences 9
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12 August 2022
SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G., Blume, A., Demirel, F.G., Bulut, S., Popp, O., Mertins, P. and Tursun, B.
Biotechniques 73
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June 2022
Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G., Popp, O., Mertins, P. and Tursun, B.
Biotechniques 72
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May 2022
AQUA mutant protein quantification of endomyocardial biopsy-sized samples from a patient with hypertrophic cardiomyopathy.
Becker, E., Francino, A., Pich, A., Perrot, A., Kraft, T. and Radocaj, A.
Frontiers in Cardiovascular Medicine 9
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21 February 2022
Claudin-targeted suicide gene therapy for claudin-overexpressing tumor cells by using modified clostridium perfringens enterotoxin (CPE).
Beier, L.S., Piontek, J., Piontek, A., Protze, J., Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521
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23 June 2022
Crosstalk between the renin-angiotensin, complement and kallikrein-kinin systems in inflammation.
Bekassy, Z., Lopatko Fagerström, I., Bader, M. and Karpman, D.
Nature Reviews Immunology 22
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July 2022
Human primary muscle stem cells regenerate injured urethral sphincter in athymic rats.
Bekele, B.M., Schöwel-Wolf, V., Kieshauer, J., Marg, A., Busjahn, A., Davis, S., Nugent, G., Ebert, A.K. and Spuler, S.
Animal Models and Experimental Medicine 5
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October 2022
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
Belda, E., Voland, L., Tremaroli, V., Falony, G., Adriouch, S., Assmann, K.E., Prifiti, E., Aron-Wisnewsky, J., Debédat, J., Le Roy, T., Nielsen, T., Amouyal, C., André, S., Andreelli, F., Blüher, M., Chakaroun, R., Chilloux, J., Coelho, L.P., Dao, M.C., Das, P., Fellahi, S., Forslund, S., Galleron, N., Hansen, T.H., Holmes, B., Ji, B., Krogh Pedersen, H., Le, P., Le Chatelier, E., Lewinter, C., Mannerås-Holm, L., Marquet, F., Myridakis, A., Pelloux, V., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J.E., Sokolovska, N., Søndertoft, N.B., Touch, S., Vieira-Silva, S., Galan, P., Holst, J., Gøtze, J.P., Køber, L., Vestergaard, H., Hansen, T., Hercberg, S., Oppert, J.M., Nielsen, J., Letunic, I., Dumas, M.E., Stumvoll, M., Pedersen, O.B., Bork, P., Ehrlich, S.D., Zucker, J.D., Bäckhed, F., Raes, J. and Clément, K.
Gut 71
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7 November 2022
Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.
Benaglio, P., Zhu, H., Okino, M.L., Yan, J., Elgamal, R., Nariai, N., Beebe, E., Korgaonkar, K., Qiu, Y., Donovan, M.K.R., Chiou, J., Wang, G., Newsome, J., Kaur, J., Miller, M., Preissl, S., Corban, S., Aylward, A., Taipale, J., Ren, B., Frazer, K.A., Sander, M. and Gaulton, K.J.
Cell Genomics 2
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14 December 2022
In memoriam: Stephen B. McMahon, PhD, FMedSci December 21, 1954 to October 9, 2021.
Bennett, D.L.H., Bradbury, E.J., Lewin, G.R. and Rice, A.S.C.
Pain 163
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March 2022
Association between B-cell depletion and attack risk in neuromyelitis optica spectrum disorder: An exploratory analysis from N-MOmentum, a double-blind, randomised, placebo-controlled, multicentre phase 2/3 trial.
Bennett, J.L., Aktas, O., Rees, W.A., Smith, M.A., Gunsior, M., Yan, L., She, D., Cimbora, D., Pittock, S.J., Weinshenker, B.G., Paul, F., Marignier, R., Wingerchuk, D., Cutter, G., Green, A., Hartung, H.P., Kim, H.J., Fujihara, K., Levy, M., Katz, E. and Cree, B.A.C.
EBioMedicine 86
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December 2022
Electrocardiographic changes during initiation of lithium augmentation of antidepressant pharmacotherapy.
Berger, M., Kermer, J., Behr, J., Schulz-Menger, J., Bilal, S., Osterland, S.L., O'Malley, G., Bschor, T., Schlattmann, P., Stamm, T., Steinacher, B., de Millas, W., Richter, C., Heinz, A., Adli, M., Buspavanich, P. and Ricken, R.
Journal of Clinical Psychopharmacology 42
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January 2022
Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Berlak, M., Tucker, E., Dorel, M., Winkler, A., McGearey, A., Rodriguez-Fos, E., da Costa, B.M., Barker, K., Fyle, E., Calton, E., Eising, S., Ober, K., Hughes, D., Koutroumanidou, E., Carter, P., Stankunaite, R., Proszek, P., Jain, N., Rosswog, C., Dorado-Garcia, H., Molenaar, J.J., Hubank, M., Barone, G., Anderson, J., Lang, P., Deubzer, H.E., Künkele, A., Fischer, M., Eggert, A., Kloft, C., Henssen, A.G., Boettcher, M., Hertwig, F., Blüthgen, N., Chesler, L. and Schulte, J.H.
Molecular Cancer 21
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10 June 2022
Impact of the external school food environment on the associations of internal school food environment with high schoolers’ diet and BMI.
Betts, G.M., Schwedhelm, C., Lipsky, L.M., Haynie, D.L. and Nansel, T.R.
Public Health Nutrition 25
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November 2022
Elevated blood pressure in pregnant women with gestational diabetes according to the WHO criteria: importance of overweight.
Birukov, A., Glintborg, D., Schulze, M.B., Jensen, T.K., Kuxhaus, O., Andersen, L.B., Kräker, K., Polemiti, E., Jensen, B.L., Jørgensen, J.S., Dechend, R. and Andersen, M.S.
Journal of Hypertension 40
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August 2022
The single-cell transcriptional landscape of lung carcinoid tumors.
Bischoff, P., Trinks, A., Wiederspahn, J., Obermayer, B., Pett, J.P., Jurmeister, P., Elsner, A., Dziodzio, T., Rückert, J.C., Neudecker, J., Falk, C., Beule, D., Sers, C., Morkel, M., Horst, D., Klauschen, F. and Blüthgen, N.
International Journal of Cancer 150
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15 June 2022
Second-line tisagenlecleucel or standard care in aggressive B-cell lymphoma.
Bishop, M.R., Dickinson, M., Purtill, D., Barba, P., Santoro, A., Hamad, N., Kato, K., Sureda, A., Greil, R., Thieblemont, C., Morschhauser, F., Janz, M., Flinn, I., Rabitsch, W., Kwong, Y.L., Kersten, M.J, Minnema, M.C., Holte, H., Chan, E.H.L., Martinez-Lopez, J., Müller, A.M.S., Maziarz, R.T., McGuirk, J.P., Bachy, E., Le Gouill, S., Dreyling, M., Harigae, H., Bond, D., Andreadis, C., McSweeney, P., Kharfan-Dabaja, M., Newsome, S., Degtyarev, E., Awasthi, R., Del Corral, C., Andreola, G., Masood, A., Schuster, S.J., Jäger, U., Borchmann, P. and Westin, J.R.
New England Journal of Medicine 386
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17 February 2022
Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation.
Blassberg, R., Patel, H., Watson, T., Gouti, M., Metzis, V., Delás, M.J. and Briscoe, J.
Nature Cell Biology 24
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May 2022
Impact of dietary intervention on serum neurofilament light chain in multiple sclerosis.
Bock, M., Steffen, F., Zipp, F. and Bittner, S.
Neurology Neuroimmunology & Neuroinflammation 9
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January 2022
Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T., Funck, K., Wollweber, F., Lisicki, E., von der Malsburg, K., von der Malsburg, A., Laborenz, J., Noel, J.K., Hessenberger, M., Jungbluth, S., Bernert, C., Kunz, S., Riedel, D., Lilie, H., Jakobs, S., van der Laan, M. and Daumke, O.
Science Advances 8
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2 September 2022
Up next: the dawn of systems biology in HFpEF research.
Bode, D., Sotomayor-Flores, C. and Schiattarella, G.G.
Journal of Molecular and Cellular Cardiology 168
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July 2022
SLM2 is a novel cardiac splicing factor involved in heart failure due to dilated cardiomyopathy.
Boeckel, J.N., Möbius-Winkler, M., Müller, M., Rebs, S., Eger, N., Schoppe, L., Tappu, R., Kokot, K.E., Kneuer, J.M., Gaul, S., Bordalo, D.M., Lai, A., Haas, J., Ghanbari, M., Drewe-Boss, P., Liss, M., Katus, H.A., Ohler, U., Gotthardt, M., Laufs, U., Streckfuss-Bömeke, K. and Meder, B.
Genomics Proteomics & Bioinformatics 20
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February 2022
Lifelong effect of therapy in young patients with the cOL4A5 alport missense variant p.(Gly624Asp): a prospective cohort study.
Boeckhaus, J., Hoefele, J., Riedhammer, K.M., Nagel, M., Beck, B., Choi, M., Gollasch, M., Bergmann, C., Sonntag, J.E., Troesch, V., Stock, J. and Gross, O.
Nephrology Dialysis Transplantation 37
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December 2022
Tissue engineering for the diaphragm and its various therapeutic possibilities - a systematic review.
Boehm, A.K., Hillebrandt, K.H., Dziodzio, T., Krenzien, F., Neudecker, J., Spuler, S., Pratschke, J., Sauer, I.M. and Andreas, M.N.
Advanced Therapeutics 5
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18 August 2022
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging.
Bogeska, R., Mikecin, A.M., Kaschutnig, P., Fawaz, M., Büchler-Schäff, M., Le, D., Ganuza, M., Vollmer, A., Paffenholz, S.V., Asada, N., Rodriguez-Correa, E., Frauhammer, F., Buettner, F., Ball, M., Knoch, J., Stäble, S., Walter, D., Petri, A., Carreño-Gonzalez, M.J., Wagner, V., Brors, B., Haas, S., Lipka, D.B., Essers, M.A.G., Weru, V., Holland-Letz, T., Mallm, J.P., Rippe, K., Krämer, S., Schlesner, M., McKinney Freeman, S., Florian, M.C., King, K.Y., Frenette, P.S., Rieger, M.A. and Milsom, M.D.
Cell Stem Cell 29
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4 August 2022
Full-length spatial transcriptomics reveals the unexplored isoform diversity of the myocardium post-MI.
Boileau, E., Li, X., Naarmann-de Vries, I.S., Becker, C., Casper, R., Altmüller, J., Leuschner, F. and Dieterich, C.
Frontiers in Genetics 13
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22 July 2022
pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation.
Boix, O., Martinez, M., Vidal, S., Giménez-Alejandre, M., Palenzuela, L., Lorenzo-Sanz, L., Quevedo, L., Moscoso, O., Ruiz-Orera, J., Ximénez-Embún, P., Ciriaco, N., Nuciforo, P., Stephan-Otto Attolini, C., Albà, M.M., Muñoz, J., Tian, T.V., Varela, I., Vivancos, A., Ramón Y Cajal, S., Muñoz, P., Rivas, C. and Abad, M.
Nature Communications 13
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11 November 2022
The impact of membrane protein diffusion on GPCR signaling.
Boltz, H.H., Sirbu, A., Stelzer, N., de Lanerolle, P., Winkelmann, S. and Annibale, P.
Cells 11
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17 May 2022
Examination of the contributions of maternal/placental-derived galectin-1 to pregnancy outcome.
Borowski, S., Freitag, N., Urban, I., Michel, G., Barrientos, G. and Blois, S.M.
Methods in Molecular Biology 2442
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2022
Association of cholinesterase activities and POD in older adult abdominal surgical patients.
Bosancic, Z., Spies, C.D., Müller, A., Winterer, G., Piper, S.K. and Heinrich, M.
BMC Anesthesiology 22
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16 September 2022
Glucose-induced hemodynamic and metabolic response of skeletal muscle in heart failure patients with reduced vs. preserved ejection fraction-a pilot study.
Boschmann, M., Klug, L., Edelmann, F., Sandek, A., von Haehling, S., Düngen, H.D., Springer, J., Anker, S.D., Doehner, W. and Jauert, N.
Journal of Cardiovascular Development and Disease 9
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13 December 2022
Genotype and intensive pretreatment influence outcome of acute myeloid leukemia patients treated with venetoclax in combination with hypomethylating agents or low-dose cytarabine: "real world" data from germany.
Braitsch, K., Schmalbrock, L.K., Jung, P., Bumeder, I., Kiewe, P., Hecker, J.S., Verbeek, M., Westermann, J., Bullinger, L., Keller, U., Bassermann, F., Krönke, J., Götze, K.S. and Rieger, K.
HemaSphere 6
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September 2022
Conditioning with fludarabine and treosulfan compared to FLAMSA-RIC in allogeneic stem cell transplantation for myeloid malignancies: a retrospective single-center analysis.
Braitsch, K., Schwarz, A., Koch, K., Hubbuch, M., Menzel, H., Keller, U., Götze, K.S., Bassermann, F., Herhaus, P. and Verbeek, M.
Annals of Hematology 101
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June 2022
Central stress processing, T-cell responsivity to stress hormones, and disease severity in multiple sclerosis.
Brasanac, J., Hetzer, S., Asseyer, S., Kuchling, J., Bellmann-Strobl, J., Ritter, K., Gamradt, S., Scheel, M., Haynes, J.D., Brandt, A.U., Paul, F., Gold, S.M. and Weygandt, M.
Brain Communications 4
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4 April 2022
Immune signature of multiple sclerosis-associated depression.
Brasanac, J., Ramien, C., Gamradt, S., Tänzer, A., Glau, L., Ritter, K., Patas, K., Agorastos, A., Wiedemann, K., Demiralay, C., Fischer, F., Otte, C., Bellmann-Strobl, J., Friese, M.A., Tolosa, E., Paul, F., Heesen, C., Weygandt, M. and Gold, S.M.
Brain Behavior and Immunity 100
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February 2022
Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways.
Braun, T., Glass, M., Wahnschaffe, L., Otte, M., Mayer, P., Franitza, M., Altmüller, J., Hallek, M., Hüttelmaier, S., Schrader, A. and Herling, M.
Haematologica 107
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January 2022
Noncanonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemia.
Braun, T., Stachelscheid, J., Bley, N., Oberbeck, S., Otte, M., Müller, T.A., Wahnschaffe, L., Glaß, M., Ommer, K., Franitza, M., Gathof, B., Altmüller, J., Hallek, M., Auguin, D., Hüttelmaier, S., Schrader, A. and Herling, M.
Cancer Research 82
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1 May 2022
Relapse of NPM1-mutated AML with extramedullary manifestation 17 years after allogeneic hematopoietic stem cell transplantation.
Braune, J., Rieger, K., Blau, O., Keller, U., Bullinger, L. and Krönke, J.
Case Reports in Hematology 2022
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28 December 2022
TIGIT blockade repolarizes AML-associated TIGIT(+) M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis.
Brauneck, F., Fischer, B., Witt, M., Muschhammer, J., Oelrich, J., da Costa Avelar, P.H., Tsoka, S., Bullinger, L., Seubert, E., Smit, D.J., Bokemeyer, C., Ackermann, C., Wellbrock, J., Haag, F. and Fiedler, W.
Journal for ImmunoTherapy of Cancer 10
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22 December 2022
Claudin-10a deficiency shifts proximal tubular Cl(-) permeability to cation selectivity via claudin-2 redistribution.
Breiderhoff, T., Himmerkus, N., Meoli, L., Fromm, A., Sewerin, S., Kriuchkova, N., Nagel, O., Ladilov, Y., Krug, S., Quintanova, C., Stumpp, M., Garbe-Schönberg, D., Westernströer, U., Merkel, C., Brinkhus, M., Altmüller, J., Schweiger, M., Mueller, D., Mutig, K., Morawski, M., Halbritter, J., Milatz, S., Bleich, M. and Günzel, D.
Journal of the American Society of Nephrology 33
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April 2022
The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.
Breimann, L., Morao, A.K., Kim, J., Jimenez, D.S., Maryn, N., Bikkasani, K., Carrozza, M.J., Albritton, S.E., Kramer, M., Street, L.A., Cerimi, K., Schumann, V.F., Bahry, E., Preibisch, S., Woehler, A. and Ercan, S.
Journal of Cell Science 135
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January 2022
Optimization of synthetic molecular reporters for a mesenchymal glioblastoma transcriptional program by integer programming.
Breitenbach, T., Schmitt, M.J. and Dandekar, T.
Bioinformatics 38
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1 September 2022
Autophagy limits inflammatory gene expression through targeting of nuclear p65/RelA by LC3 and p62 for lysosomal degradation.
Brischetto, C., Mucka, P., Kaergel, E. and Scheidereit, C.
bioRxiv
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2 November 2022
Taking out the trash: How misfolded proteins are removed from the endoplasmic reticulum.
Brodsky, J.L., Engelman, D.M., Hendershot, L.M., Piana-Agostinetti, S. and Sommer, T.
Faculty Reviews 11
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5 October 2022
Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs.
Broto, M., Kaminski, M.M., Adrianus, C., Kim, N., Greensmith, R., Dissanayake-Perera, S., Schubert, A.J., Tan, X., Kim, H., Dighe, A.S., Collins, J.J. and Stevens, M.M.
Nature Nanotechnology 17
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October 2022
Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis.
Brune, S., Høgestøl, E.A., de Rodez Benavent, S.A., Berg-Hansen, P., Beyer, M.K., Leikfoss, I.S., Bos, S.D., Sowa, P., Brunborg, C., Andorra, M., Pulido Valdeolivas, I., Asseyer, S., Brandt, A., Chien, C., Scheel, M., Blennow, K., Zetterberg, H., Kerlero de Rosbo, N., Paul, F., Uccelli, A., Villoslada, P., Berge, T. and Harbo, H.F.
Multiple Sclerosis Journal 28
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October 2022
Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation.
Brunner, A.D., Thielert, M., Vasilopoulou, C., Ammar, C., Coscia, F., Mund, A., Hoerning, O.B., Bache, N., Apalategui, A., Lubeck, M., Richter, S., Fischer, D.S., Raether, O., Park, M.A., Meier, F., Theis, F.J. and Mann, M.
Molecular Systems Biology 18
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1 March 2022
Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Buchanan, C.J., Gaunt, B., Harrison, P.J., Yang, Y., Liu, J., Khan, A., Giltrap, A.M., Le Bas, A., Ward, P.N., Gupta, K., Dumoux, M., Tan, T.K., Schimaski, L., Daga, S., Picchiotti, N., Baldassarri, M., Benetti, E., Fallerini, C., Fava, F., Giliberti, A., Koukos, P.I., Davy, M.J., Lakshminarayanan, A., Xue, X., Papadakis, G., Deimel, L.P., Casablancas-Antràs, V., Claridge, T.D.W., Bonvin, A.M.J.J., Sattentau, Q.J., Furini, S., Gori, M., Huo, J., Owens, R.J., Schaffitzel, C., Berger, I., Renieri, A., Naismith, J.H., Baldwin, A.J. and Davis, B.G.
Science 377
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22 July 2022
The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.
Buffenstein, R., Amoroso, V., Andziak, B., Avdieiev, S., Azpurua, J., Barker, A.J., Bennett, N.C., Brieño-Enríquez, M.A., Bronner, G.N., Coen, C., Delaney, M.A., Dengler-Crish, C.M., Edrey, Y.H., Faulkes, C.G., Frankel, D., Friedlander, G., Gibney, P.A., Gorbunova, V., Hine, C., Holmes, M.M., Jarvis, J.U.M., Kawamura, Y., Kutsukake, N., Kenyon, C., Khaled, W.T., Kikusui, T., Kissil, J., Lagestee, S., Larson, J., Lauer, A., Lavrenchenko, L.A., Lee, A., Levitt, J.B., Lewin, G.R., Lewis Hardell, K.N., Lin, T.D., Mason, M.J., McCloskey, D., McMahon, M., Miura, K., Mogi, K., Narayan, V., O'Connor, T.P., Okanoya, K., O'Riain, M.J., Park, T.J., Place, N.J., Podshivalova, K., Pamenter, M.E., Pyott, S.J., Reznick, J., Ruby, J.G., Salmon, A.B., Santos-Sacchi, J., Sarko, D.K., Seluanov, A., Shepard, A., Smith, M., Storey, K.B., Tian, X., Vice, E.N., Viltard, M., Watarai, Ak., Wywial, E., Yamakawa, M., Zemlemerova, E.D., Zions, M. and Smith, E.S.J.
Biological Reviews 97
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February 2022
The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression.
Bujanic, L., Shevchuk, O., von Kügelgen, N., Kalinina, A., Ludwik, K., Koppstein, D., Zerna, N., Sickmann, A. and Chekulaeva, M.
RNA 28
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May 2022
CEBPA mutations in AML: site matters.
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Blood 139
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Generation of redirected engineered human chimeric antigen receptor (CAR) T cells.
Bunse, M. and Höpken, U.E.
Methods in Molecular Biology 2521
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23 June 2022
Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA interdisciplinary expert consensus.
Buske, C., Dreyling, M., Alvarez-Larrán, A., Apperley, J., Arcaini, L., Besson, C., Bullinger, L., Corradini, P., Della Porta, M.G., Dimopoulos, M., D’Sa, S., Eich, H.T., Foà, R., Ghia, P., Gomes da Silva, M., Gribben, J., Hajek, R., Harrison, C., Heuser, M., Kiesewetter, B., Kiladjian, J.J., Kröger, N., Moreau, P., Passweg, J.R., Peyvandi, F., Rea, D., Ribera, J.M., Robak, T., San-Miguel, J.F., Santini, V., Sanz, G., Sonneveld, P., von Lilienfeld-Toal, M., Wendtner, C., Pentheroudakis, G. and Passamonti, F.
ESMO Open 7
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April 2022
Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I., Jaeschke, L., Nimptsch, K., Janke, J., Herrmann, P., Kobelt, D., Kielstein, H., Pischon, T. and Stein, U.
International Journal of Oncology 60
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February 2022
Immune competence and spleen size scale with colony
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Bégay, V., Cirovic, B., Barker, A.J., Klopffleisch, R., Hart, D.W., Bennett, N.C. and Lewin, G.R.
Open Biology 12
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6 April 2022
WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephaly.
Bögershausen, N., Krawczyk, H.E., Jamra, R.A., Lin, S.J., Yigit, G., Hüning, I., Polo, A.M., Vona, B., Huang, K., Schmidt, J., Altmüller, J., Luppe, J., Platzer, K., Dörgeloh, B.B., Busche, A., Biskup, S., Mendes, M.I., Smith, D.E.C., Salomons, G.S., Zibat, A., Bültmann, E., Nürnberg, P., Spielmann, M., Lemke, J.R., Li, Y., Zenker, M., Varshney, G.K., Hillen, H.S., Kratz, C.P. and Wollnik, B.
Human Mutation 43
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Organoids as tools for fundamental discovery and translation - a Keystone Symposia report.
Cable, J., Lutolf, M.P., Fu, J., Park, S.E., Apostolou, A., Chen, S., Song, C.J., Spence, J.R., Liberali, P., Lancaster, M., Meier, A.B., Pek, N.M.Q., Wells, J.M., Capeling, M.M., Uzquiano, A., Musah, S., Huch, M., Gouti, M., Hombrink, P., Quadrato, G. and Urenda, J.P.
Annals of the New York Academy of Sciences 1518
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December 2022
Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
Cabral-Marques, O., Halpert, G., Schimke, L.F., Ostrinski, Y., Vojdani, A., Baiocchi, G.C., Freire, P.P., Filgueiras, I.S., Zyskind, I., Lattin, M.T., Tran, F., Schreiber, S., Marques, A.H.C., Plaça, D.R., Fonseca, D.L.M., Humrich, J.Y., Müller, A., Giil, L.M., Graßhoff, H., Schumann, A., Hackel, A., Junker, J., Meyer, C., Ochs, H.D., Lavi, Y.B., Scheibenbogen, C., Dechend, R., Jurisica, I., Schulze-Forster, K., Silverberg, J.I., Amital, H., Zimmerman, J., Heidecke, H., Rosenberg, A.Z., Riemekasten, G. and Shoenfeld, Y.
Nature Communications 13
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9 March 2022
Metaproteomics approach and pathway modulation in obesity and diabetes: a narrative review.
Calabrese, F.M., Porrelli, A., Vacca, M., Comte, B., Nimptsch, K., Pinart, M., Pischon, T., Pujos-Guillot, E. and De Angelis, M.
Nutrients 14
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January 2022
Cardiac metabolism in HFpEF: from fuel to signalling.
Capone, F., Sotomayor-Flores, C., Bode, D., Wang, R., Rodolico, D., Strocchi, S. and Schiattarella, G.G.
Cardiovascular Research 118
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December 2022
AKAP18δ anchors and regulates CaMKII activity at phospholamban-SERCA2 and RYR.
Carlson, C.R., Aronsen, J.M., Bergan-Dahl, A., Moutty, M.C., Lunde, M., Lunde, P.K., Jarstadmarken, H., Wanichawan, P., Pereira, L., Kolstad, T.R.S., Dalhus, B., Subramanian, H., Hille, S., Christensen, G., Müller, O.J., Nikolaev, V., Bers, D.M., Sjaastad, I., Shen, X., Louch, W.E., Klussmann, E. and Sejersted, O.M.
Circulation Research 130
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7 January 2022
Seasonal variation in attacks of neuromyelitis optica spectrum disorders and multiple sclerosis: evaluation of 794 attacks from a nationwide registry in Argentina.
Carnero Contentti, E., Lopez, P.A., Pettinicchi, J.P., Criniti, J., Pappolla, A., Miguez, J., Patrucco, L., Cristiano, E., Liwacki, S., Tkachuk, V., Balbuena, M.E., Vrech, C., Deri, N., Correale, J., Marrodan, M., Ysrraelit, M.C., Leguizamon, F., Luetic, G., Menichini, M.L., Tavolini, D., Mainella, C., Zanga, G., Burgos, M., Hryb, J., Barboza, A., Lazaro, L., Alonso, R., Fernández Liguori, N., Nadur, D., Chercoff, A., Alonso Serena, M., Caride, A., Paul, F. and Rojas, J.I.
Multiple Sclerosis and Related Disorders 58
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February 2022
The blood-brain barrier-a metabolic ecosystem.
Castro, M. and Potente, M.
EMBO Journal 41
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2 May 2022
Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
Cefalu, W.T., Andersen, D.K., Arreaza-Rubín, G., Pin, C.L., Sato, S., Verchere, C.B., Woo, M. and Rosenblum, N.D.
Diabetes 71
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January 2022
Building a Healthcare Alliance for Resourceful Medicine Offensive Against Neoplasms in hematologY added value framework for hematologic malignancies: a comparative analysis of existing tools.
Cerisoli, F., Ali, F., Bereczky, T., Bolaños, N., Bullinger, L., Dhanasiri, S., Gallagher, J., Pérez, S.G., Geissler, J., Guillevic, Y., Harrison, K., Naoum, A., Portulano, C., Rodríguez Vicente, A.E., Schulze-Rath, R., Gómez, G.Y., Sanz, G. and Hernández Rivas, J.M.
Value in Health 25
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October 2022
Association of maintenance intravenous immunoglobulin with prevention of relapse in adult myelin oligodendrocyte glycoprotein antibody-associated disease.
Chen, J.J., Huda, S., Hacohen, Y., Levy, M., Lotan, I., Wilf-Yarkoni, A., Stiebel-Kalish, H., Hellmann, M.A., Sotirchos, E.S., Henderson, A.D., Pittock, S.J., Bhatti, M.T., Eggenberger, E.R., Di Nome, M., Kim, H.J., Kim, S.H., Saiz, A., Paul, F., Dale, R.C., Ramanathan, S., Palace, J., Camera, V., Leite, M.I., Lam, B.L., Bennett, J.L., Mariotto, S., Hodge, D., Audoin, B., Maillart, E., Deschamps, R., Pique, J., Flanagan, E.P. and Marignier, R.
JAMA Neurology 79
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1 May 2022
OCT retinal nerve fiber layer thickness differentiates acute optic neuritis from MOG antibody-associated disease and Multiple Sclerosis: RNFL thickening in acute optic neuritis from MOGAD vs MS.
Chen, J.J., Sotirchos, E.S., Henderson, A.D., Vasileiou, E.S., Flanagan, E.P., Bhatti, M.T., Jamali, S., Eggenberger, E.R., Dinome, M., Frohman, L.P., Arnold, A.C., Bonelli, L., Seleme, N., Mejia-Vergara, A.J., Moss, H.E., Padungkiatsagul, T., Stiebel-Kalish, H., Lotan, I., Hellmann, M.A., Hodge, D., Oertel, F.C., Paul, F., Saidha, S., Calabresi, P.A. and Pittock, S.J.
Multiple Sclerosis and Related Disorders 58
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February 2022
Oxidative RNA damage in the pathogenesis and treatment of type 2 diabetes.
Chen, X., Yu, H., Li, Z., Ye, W., Liu, Z., Gao, J., Wang, Y., Li, X., Zhang, L., Alenina, N., Bader, M., Ding, H., Li, P. and Aung, L.H.H.
Frontiers in Physiology 13
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28 March 2022
The intrinsic and extrinsic effects of TET proteins during gastrulation.
Cheng, S., Mittnenzweig, M., Mayshar, Y., Lifshitz, A., Dunjić, M., Rais, Y., Ben-Yair, R., Gehrs, S., Chomsky, E., Mukamel, Z., Rubinstein, H., Schlereth, K., Reines, N., Orenbuch, A.H., Tanay, A. and Stelzer, Y.
Cell 185
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18 August 2022
Physical mechanisms of chromatin spatial organization.
Chiariello, A.M., Bianco, S., Esposito, A., Fiorillo, L., Conte, M., Irani, E., Musella, F., Abraham, A., Prisco, A. and Nicodemi, M.
FEBS Journal 289
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March 2022
Prediction of high and low disease activity in early MS patients using multiple kernel learning identifies importance of lateral ventricle intensity.
Chien, C., Seiler, M., Eitel, F., Schmitz-Hübsch, T., Paul, F. and Ritter, K.
Multiple Sclerosis Journal Experimental Translational and Clinical 8
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1 July 2022
Motor signature of autism spectrum disorder in adults without intellectual impairment.
Cho, A.B., Otte, K., Baskow, I., Ehlen, F., Maslahati, T., Mansow-Model, S., Schmitz-Hübsch, T., Behnia, B. and Roepke, S.
Scientific Reports 12
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10 May 2022
A high-resolution map of human RNA translation.
Chothani, S.P., Adami, E., Widjaja, A.A., Langley, S.R., Viswanathan, S., Pua, C.J., Zhihao, N.T., Harmston, N., D'Agostino, G., Whiffin, N., Mao, W., Ouyang, J.F., Lim, W.W., Lim, S., Lee, C.Q.E., Grubman, A., Chen, J., Kovalik, J.P., Tryggvason, K., Polo, J.M., Ho, L., Cook, S.A., Rackham, O.J.L. and Schafer, S.
Molecular Cell 82
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4 August 2022
Modeling clonal hematopoiesis in umbilical cord blood cells by CRISPR/Cas9.
Christen, F., Hablesreiter, R., Hoyer, K., Hennch, C., Maluck-Böttcher, A., Segler, A., Madadi, A., Frick, M., Bullinger, L., Briest, F. and Damm, F.
Leukemia 36
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April 2022
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki, F., Bjordahl, R., Goodridge, J.P., Mahmood, S., Gaidarova, S., Abujarour, R., Davis, Z.B., Merino, A., Tuininga, K., Wang, H., Kumar, A., Groff, B., Witty, A., Bonello, G., Huffman, J., Dailey, T., Lee, T.T., Malmberg, K.J., Walcheck, B., Höpken, U., Rehm, A., Valamehr, B. and Miller, J.S.
Nature Communications 13
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29 November 2022
A novel complex genomic rearrangement affecting the KCNJ2 regulatory region causes a variant of Cooks syndrome.
Cinque, L., Micale, L., Manara, E., Esposito, A., Palumbo, O., Chiariello, A.M., Bianco, S., Guerri, G., Bertelli, M., Giuffrida, M.G., Bernardini, L., Notarangelo, A., Nicodemi, M. and Castori, M.
Human Genetics 141
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February 2022
Simultaneous genetic ablation of PD-1, LAG-3, and TIM-3 in CD8 T cells delays tumor growth and improves survival outcome.
Ciraolo, E., Althoff, S., Ruß, J., Rosnev, S., Butze, M., Pühl, M., Frentsch, M., Bullinger, L. and Na, I.K.
International Journal of Molecular Sciences 23
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16 March 2022
Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6.
Cockman, M.E., Sugimoto, Y., Pegg, H.B., Masson, N., Salah, E., Tumber, A., Flynn, H.R., Kirkpatrick, J.M., Schofield, C.J. and Ratcliffe, P.J.
Proceedings of the National Academy of Sciences of the United States of America 119
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9 August 2022
Towards the biogeography of prokaryotic genes.
Coelho, L.P., Alves, R., Del Río, Á.R., Myers, P.N., Cantalapiedra, C.P., Giner-Lamia, J., Schmidt, T.S., Mende, D.R., Orakov, A., Letunic, I., Hildebrand, F., Van Rossum, T., Forslund, S.K., Khedkar, S., Maistrenko, O.M., Pan, S., Jia, L., Ferretti, P., Sunagawa, S., Zhao, X.M., Nielsen, H.B., Huerta-Cepas, J. and Bork, P.
Nature 601
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13 January 2022
Single cell‐ and spatial 'omics revolutionize physiology.
Conrad, T. and Altmüller, J.
Acta Physiologica
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2 June 2022
Polymer models of chromatin imaging data in single cells.
Conte, M., Chiariello, A.M., Abraham, A., Bianco, S., Esposito, A., Nicodemi, M., Matteuzzi, T. and Vercellone, F.
Algorithms 15
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16 September 2022
Efficient computational implementation of polymer physics models to explore chromatin structure.
Conte, M., Esposito, A., Fiorillo, L., Campanile, R., Annunziatella, C., Corrado, A., Chiariello, M.G., Bianco, S. and Chiariello, A.M.
International Journal of Parallel, Emergent and Distributed Systems 37
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January 2022
A polymer physics model to dissect genome organization in healthy and pathological phenotypes.
Conte, M., Fiorillo, L., Bianco, S., Chiariello, A.M., Esposito, A., Musella, F., Flora, F., Abraham, A. and Nicodemi, M.
Methods in Molecular Biology 2301
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2022
Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding.
Conte, M., Irani, E., Chiariello, A.M., Abraham, A., Bianco, S., Esposito, A. and Nicodemi, M.
Nature Communications 13
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13 July 2022
Differences in age-related retinal and cortical atrophy rates in multiple sclerosis.
Cordano, C., Nourbakhsh, B., Yiu, H.H., Papinutto, N., Caverzasi, E., Abdelhak, A., Oertel, F.C., Beaudry-Richard, A., Santaniello, A., Sacco, S., Bennett, D.J., Gomez, A., Sigurdson, C.J., Hauser, S.L., Magliozzi, R., Cree, B.A.C., Henry, R.G. and Green, A.J.
Neurology 99
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11 October 2022
Reply to "Interpretation of longitudinal changes of the inner nuclear layer in MS".
Cordano, C., Yiu, H.H., Abdelhak, A., Beaudry-Richard, A., Oertel, F.C. and Green, A.J.
Annals of Neurology 92
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July 2022
Hypothalamic galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop.
Corradi, L., Bruzzone, M., Maschio, M.D., Sawamiphak, S. and Filosa, A.
Current Biology 32
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11 April 2022
Using pERK immunostaining to quantify neuronal activity induced by stress in zebrafish larvae.
Corradi, L., Zaupa, M., Sawamiphak, S. and Filosa, A.
STAR Protocols 3
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16 December 2022
Retinoids are not linked to risk of multiple sclerosis: a Danish nationwide cohort study.
Cortes-Figueiredo, F., Nielsen, N.M., Stenager, E., Paul, F., Hallas, J. and Kristensen, K.B.
European Journal of Neurology 2
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18 January 2022
Combining callers improves the detection of copy number variants from whole-genome sequencing.
Coutelier, M., Holtgrewe, M., Jäger, M., Flöttman, R., Mensah, M.A., Spielmann, M., Krawitz, P., Horn, D., Beule, D. and Mundlos, S.
European Journal of Human Genetics 30
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February 2022
Svep1 stabilises developmental vascular anastomosis in reduced flow conditions.
Coxam, B., Collins, R.T., Hußmann, M., Huisman, Y., Meier, K., Jung, S., Bartels-Klein, E., Szymborska, A., Finotto, L., Helker, C.S.M., Stainier, D.Y.R., Schulte-Merker, S. and Gerhardt, H.
Development 149
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24 March 2022
Myogenic vasoconstriction requires canonical G(q/11) signaling of the angiotensin II type 1 receptor.
Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y.M., Schleifenbaum, J., Bader, M., Welsh, D.G., Huang, Y. and Gollasch, M.
Journal of the American Heart Association 11
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15 February 2022
Associations of ultra-processed food intake with maternal weight change and cardiometabolic health and infant growth.
Cummings, J.R., Lipsky, L.M., Schwedhelm, C., Liu, A. and Nansel, T.R.
International Journal of Behavioral Nutrition and Physical Activity 19
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26 May 2022
Hemostatic management in an infant with neuroblastoma and severe hemophilia B with extended half-life recombinant factor IX fusion protein.
Cuntz, F., Deubzer, H.E., Schulte, J.H., Nimtz-Talaska, A., Eggert, A. and Holzhauer, S.
Journal of Pediatric Hematology Oncology 44
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1 January 2022
D
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Dahale, S., Ruiz-Orera, J., Silhavy, J., Hübner, N., van Heesch, S., Pravenec, M. and Atanur, S.S.
Life Science Alliance 5
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April 2022
Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M., Monks, A., Harris, E.D., Kobelt, D., Osterland, M., Khaireddine, F., Herrmann, P., Kemmner, W., Burock, S., Walther, W., Shoemaker, R.H. and Stein, U.
Cancers 14
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2022
Brentuximab vedotin-containing escalated BEACOPP variants for newly diagnosed advanced-stage classical Hodgkin lymphoma: follow-up analysis of a randomized phase II study from the German Hodgkin Study Group.
Damaschin, C., Goergen, H., Kreissl, S., Plütschow, A., Breywisch, F., Mathas, S., Meissner, J., Sökler, M., Topp, M.S., Vucinic, V., Zimmermann, A., von Tresckow, B., Fuchs, M., Engert, A., Borchmann, P. and Eichenauer, D.A.
Leukemia 36
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February 2022
Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases.
Damerau, A., Kirchner, M., Pfeiffenberger, M., Ehlers, L., Do Nguyen, D.H., Mertins, P., Bartek, B., Maleitzke, T., Palmowski, Y., Hardt, S., Winkler, T., Buttgereit, F. and Gaber, T.
Metabolic Engineering 72
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July 2022
Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19.
Dannebaum, R., Suwalski, P., Asgharian, H., Du Zhipei, G., Lin, H., Weiner, J., Holtgrewe, M., Thibeault, C., Müller, M., Wang, X., Karadeniz, Z., Saccomanno, J., Doehn, J.M., Hübner, R.H., Hinzmann, B., Blüher, A., Siemann, S., Telman, D., Suttorp, N., Witzenrath, M., Hippenstiel, S., Skurk, C., Poller, W., Sander, L.E., Beule, D., Kurth, F., Guettouche, T., Landmesser, U., Berka, J., Luong, K., Rubelt, F. and Heidecker, B.
EClinicalMedicine 48
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June 2022
SPFH protein cage - one ring to rule them all.
Daumke, O. and Lewin, G.R.
Cell Research 32
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February 2022
Diagnostik, Therapie und die Bedeutung der Lebensqualität von Patienten mit chronischem Koronarsyndrom [Diagnostics, therapy and the importance of quality of life in patients with chronic coronary syndrome. Results oft the general practitioner care study ALTHEA].
Dechend, R.
MMW Fortschritte der Medizin 164
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22 April 2022
Endothelin antagonists and the quest for a new therapeutic option in resistant hypertension.
Dechend, R. and Delles, C.
Lancet 400
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3 December 2022
Salt, aldosterone, and the renin-angiotensin system in pregnancy.
Dechend, R., Lamarca, B. and Davidge, S.T.
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Detailed stratified GWAS analysis for severe COVID-19 in four European populations.
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Human Molecular Genetics 31
(23): 3945-3966.
1 December 2022
Intranasal SARS-CoV-2 spike-based immunisation adjuvanted with polyethyleneimine elicits mucosal and systemic humoral responses in mice.
Deimel, L.P., Liu, X., Gilbert-Jaramillo, J., Liu, S., James, W.S. and Sattentau, Q.J.
Journal of Immunological Methods 511
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December 2022
Shared sugars - parasite glycan homology in HIV-1 vaccine design.
Deimel, L.P. and Sattentau, Q.J.
Trends in Parasitology 38
(7): 498-500.
July 2022
Glycans in HIV-1 vaccine design - engaging the shield.
Deimel, L.P., Xue, X. and Sattentau, Q.J.
Trends in Microbiology 30
(9): 866-881.
September 2022
High thermostability improves neutralizing antibody responses induced by native-like HIV-1 envelope trimers.
Del Moral-Sánchez, I., Russell, R.A., Schermer, E.E., Cottrell, C.A., Allen, J.D., Torrents de la Peña, A., LaBranche, C.., Kumar, S., Crispin, M., Ward, A.B., Montefiori, D.C., Sattentau, Q.J., Sliepen, K. and Sanders, R.W.
NPJ Vaccines 7
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28 February 2022
Prevalence of hypertension and possible risk factors of hypertension unawareness among individuals aged 30-75 years from two Panamanian provinces: results from population-based cross-sectional studies, 2010 and 2019.
Del Rio, A.I., Moreno Velásquez, I., Roa, R., Montenegro Mendoza, R., Motta, J. and Quintana, H.K.
PLoS ONE 17
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28 November 2022
B(1) inhomogeneity correction of RARE MRI at low SNR: quantitative in vivo (19)F MRI of mouse neuroinflammation with a cryogenically-cooled transceive surface radiofrequency probe.
Delgado, P.R., Kuehne, A., Aravina, M., Millward, J.M., Vazquez, A., Starke, L., Waiczies, H., Pohlmann, A., Niendorf, T. and Waiczies, S.
Magnetic Resonance in Medicine 87
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April 2022
Functional repertoire convergence of distantly related eukaryotic plankton lineages abundant in the sunlit ocean.
Delmont, T.O., Gaia, M., Hinsinger, D.D., Frémont, P., Vanni, C., Fernandez-Guerra, A., Eren, A.M., Kourlaiev, A., d'Agata, L., Clayssen, Q., Villar, E., Labadie, K., Cruaud, C., Poulain, J., Da Silva, C., Wessner, M., Noel, B., Aury, J.M., de Vargas, C., Bowler, C., Karsenti, E., Pelletier, E., Wincker, P. and Jaillon, O.
Cell Genomics 2
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11 May 2022
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Demel, U.M., Böger, M., Yousefian, S., Grunert, C., Zhang, L., Hotz, P.W., Gottschlich, A., Köse, H., Isaakidis, K., Vonficht, D., Grünschläger, F., Rohleder, E., Wagner, K., Dönig, J., Igl, V., Brzezicha, B., Baumgartner, F., Habringer, S., Löber, J., Chapuy, B., Weidinger, C., Kobold, S., Haas, S., Busse, A.B., Müller, S., Wirth, M., Schick, M. and Keller, U.
Journal of Clinical Investigation 132
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2 May 2022
A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo.
Demel, U.M., Lutz, R., Sujer, S., Demerdash, Y., Sood, S., Grünschläger, F., Kuck, A., Werner, P., Blaszkiewicz, S., Uckelmann, H.J., Haas, S. and Essers, M.
Blood Advances 6
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10 June 2022
Traveling volunteers: a multi-vendor, multi-center study on reproducibility and comparability of 4D flow derived aortic hemodynamics in cardiovascular magnetic resonance.
Demir, A., Wiesemann, S., Erley, J., Schmitter, S., Trauzeddel, R.F., Pieske, B., Hansmann, J., Kelle, S. and Schulz-Menger, J.
Journal of Magnetic Resonance Imaging 55
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January 2022
Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S., Bittner, A., Frick, M., Kase, J., Hoffmann, J., Trenker, C., Keller, U., Bogner, C., Hüttmann, A., Dürig, J., Janz, M., Mathas, S., Marks, R., Krohn, U., Na, I.K., Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 63
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January 2022
A deep dive into the circulating ctDNA cosmos to vanquish neuroblastoma.
Deubzer, H.E., Astrahantseff, K. and Lodrini, M.
Cancer Discovery 12
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2 December 2022
Personalisierte Medizin in der Kinderonkologie: Wo stehen wir heute?
Deubzer, H.E., Schulte, J.H. and Eggert, A.
TumorDiagnostik & Therapie 43
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February 2022
A comparison of solvent-based extraction methods to assess the central carbon metabolites in mouse bone and muscle.
Dias, D.B., Fritsche-Guenther, R., Gutmann, F., Duda, G.N., Kirwan, J. and Poh, P.S.P.
Metabolites 12
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Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
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Simultaneous imaging and flow-cytometry-based detection of multiple fluorescent senescence markers in therapy-induced senescent cancer cells.
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Uncovering the contribution of moderate-penetrance susceptibility genes to breast cancer by whole-exome sequencing and targeted enrichment sequencing of candidate genes in women of European ancestry.
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Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications.
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Altered nuclear architecture in blood cells from Huntington's disease patients.
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SMOG 2 and OpenSMOG: extending the limits of structure-based models.
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Therapeutic targets for phenolic compounds from agro-industrial by-products against obesity.
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Cell Reports 40
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TCR and CAR engineering of primary human T cells.
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Gender differences in perceptions and attitudes of medical students towards neurosurgery: a german nationwide survey.
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The anti-glucocorticoid receptor antibody clone 5E4: raising awareness of unspecific antibody binding.
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Die Rolle der Hyper- und Hypohydrogenämie im klinischen Alltag - Warum pH? [The role of hyperhydrogenemia and hypohydrogenemia in the clinical setting - Why pH?].
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An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils.
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The spontaneous course of human herpesvirus 6 DNA-associated myocarditis and the effect of immunosuppressive intervention.
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Walking parameters of older adults from a lower back inertial measurement unit, a 6-year longitudinal observational study.
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Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
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The physics of DNA folding: polymer models and phase-separation.
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Polymer physics reveals a combinatorial code linking 3D chromatin architecture to 1D chromatin states.
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Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in severe COVID-19.
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A cFLIP-flop switch for senolysis.
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Development of a machine learning approach for local-scale ozone forecasting: application to Kennewick, WA.
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Post-operative cognitive impairment: a cognitive epidemiology perspective.
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Editorial: The long road to building a head: smooth travels and accidents on the journey from patterning via morphogenesis to phenotype.
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A similarity scaling approach for organ-on-chip devices.
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Assessing evolutionary and developmental transcriptome dynamics in homologous cell types.
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Recent analytical approaches for the study of bioavailability and metabolism of bioactive phenolic compounds.
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March 2022
Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised, controlled, open-label, phase 3b trial.
Foley, J.F., Defer, G., Ryerson, L.Z., Cohen, J.A., Arnold, D.L., Butzkueven, H., Cutter, G., Giovannoni, G., Killestein, J., Wiendl, H., Smirnakis, K., Xiao, S., Kong, G., Kuhelj, R. and Campbell, N.
Lancet Neurology 21
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July 2022
Therapy switches in fingolimod-treated patients with multiple sclerosis: long-term experience from the German MS Registry.
Frahm, N., Fneish, F., Ellenberger, D., Flachenecker, P., Paul, F., Warnke, C., Kleinschnitz, C., Parciak, T., Krefting, D., Hellwig, K., Haas, J., Rommer, P.S., Stahmann, A. and Zettl, U.K.
Neurology and Therapy 11
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March 2022
The SCF/KIT axis in human mast cells: capicua acts as potent KIT repressor and ERK predominates PI3K.
Franke, K., Kirchner, M., Mertins, P., Zuberbier, T. and Babina, M.
Allergy 77
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November 2022
Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies.
Frantz, S., Hundertmark, M.J., Schulz-Menger, J., Bengel, F.M. and Bauersachs, J.
European Heart Journal 43
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14 July 2022
Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model.
Freitag, K., Sterczyk, N., Wendlinger, S., Obermayer, B., Schulz, J., Farztdinov, V., Mülleder, M., Ralser, M., Houtman, J., Fleck, L., Braeuning, C., Sansevrino, R., Hoffmann, C., Milovanovic, D., Sigrist, S.J., Conrad, T., Beule, D., Heppner, F.L. and Jendrach, M.
Journal of Neuroinflammation 19
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2 July 2022
Kardiomyopathie im Neugeborenenalter: Forschungsfortschritte eröffnen neue diagnostische Möglichkeiten [Cardiomyopathy in neonatal age: advances in research open up new diagnostic possibilities].
Frenzel, M., Klaassen, S., Klingel, K., Knirsch, W., Kretschmar, O., Kühnisch, J. and Oxenius, A.
Monatsschrift Kinderheilkunde 170
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October 2022
Dataset debt in biomedical language modeling.
Fries, J.A., Seelam, N., Altay, G., Weber, L., Kang, M., Datta, D., Su, R., Garda, S., Wang, B., Ott, S., Samwald, M. and Kusa, W.
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May 2022
Analysis of adherent cell culture lysates with low metabolite concentrations using the Biocrates AbsoluteIDQ p400 HR kit.
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Scientific Reports 12
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13 May 2022
Microbiome and metabolome features of the cardiometabolic disease spectrum.
Fromentin, S., Forslund, S.K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M.T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R., Coelho, L.P., Falony, G., Fellahi, S., Galan, P., Galleron, N., Helft, G., Hoyles, L., Isnard, R., Le Chatelier, E., Julienne, H., Olsson, L., Pedersen, H.K., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J.E., Schmidt, T.S.B., Vieira-Silva, S., Li, P., Zimmermann-Kogadeeva, M., Lewinter, C., Søndertoft, N.B., Hansen, T.H., Gauguier, D., Gøtze, J.P., Køber, L., Kornowski, R., Vestergaard, H., Hansen, T., Zucker, J.D., Hercberg, S., Letunic, I., Bäckhed, F., Oppert, J.M., Nielsen, J., Raes, J., Bork, P., Stumvoll, M., Segal, E., Clément, K., Dumas, M.E., Ehrlich, S.D. and Pedersen, O.
Nature Medicine 28
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17 February 2022
CTGF/CCN2 has a possible detrimental role in the inflammation and the remyelination failure in the early stages of multiple sclerosis.
Fuchs, L., Mausner-Fainberg, K., Luban, A., Asseyer, S.E., Golan, M., Benhamou, M., Volovitz, I., Regev, K., Vigiser, I., Piura, Y., Kolb, H., Paul, F. and Karni, A.
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15 October 2022
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A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts.
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PLoS Pathogens 18
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20 September 2022
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma.
Garces de Los Fayos Alonso, I., Zujo, L., Wiest, I., Kodajova, P., Timelthaler, G., Edtmayer, S., Zrimšek, M., Kollmann, S., Giordano, C., Kothmayer, M., Neubauer, H.A., Dey, S., Schlederer, M., Schmalzbauer, B.S., Limberger, T., Probst, C., Pusch, O., Högler, S., Tangermann, S., Merkel, O., Schiefer, A.I., Kornauth, C., Prutsch, N., Zimmerman, M., Abraham, B., Anagnostopoulos, J., Quintanilla-Martinez, L., Mathas, S., Wolf, P., Stoiber, D., Staber, P.B., Egger, G., Klapper, W., Woessmann, W., Look, T.A., Gunning, P., Turner, S.D., Moriggl, R., Lagger, S. and Kenner, L.
Molecular Cancer 21
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31 August 2022
Identification and validation of small molecule analytes in mouse plasma by liquid chromatography–tandem mass spectrometry: A case study of misidentification of a short-chain fatty acid with a ketone body.
García-Rivera, Mariel A., Fernández-Ochoa, Á., Brüning, U., Fritsche-Guenther, R. and Kirwan, J.A.
Talanta 242
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15 May 2022
Cosmeceutical potential of major tropical and subtropical fruit by-products for a sustainable revalorization.
García-Villegas, A., Rojas-García, A., Villegas-Aguilar, M.C., Fernández-Moreno, P., Fernández-Ochoa, Á., Cádiz-Gurrea, M.L., Arráez-Román, D. and Segura-Carretero, A.
Antioxidants 11
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21 January 2022
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.
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Cell Reports 38
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15 March 2022
IFN-γ-dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis.
Garnier, L., Pick, R., Montorfani, J., Sun, M., Brighouse, D., Liaudet, N., Kammertoens, T., Blankenstein, T., Page, N., Bernier-Latamani, J., Tran, N.L., Petrova, T.V., Merkler, D., Scheiermann, C. and Hugues, S.
Science Advances 8
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8 June 2022
Hypertension in pregnancy: diagnosis, blood pressure goals, and pharmacotherapy: a scientific statement from the American Heart Association.
Garovic, V.D., Dechend, R., Easterling, T., Karumanchi, S.A., McMurtry Baird, S., Magee, L.A., Rana, S., Vermunt, J.V. and August, P.
Hypertension 79
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February 2022
Vaccine-associated enhanced disease and pathogenic human coronaviruses.
Gartlan, C., Tipton, T., Salguero, F.J., Sattentau, Q., Gorringe, A. and Carroll, M.W.
Frontiers in Immunology 13
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4 April 2022
Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications.
Gawałko, M., Agbaedeng, T.A., Saljic, A., Mueller, D.N., Wilck, N., Schnabel, R., Penders, J., Rienstra, M., van Gelder, I., Jespersen, T., Schotten, U., Crijns, H.J.G.M., Kalman, J.M., Sanders, P., Nattel, S., Dobrev, D. and Linz, D.
Cardiovascular Research 118
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July 2022
Wie Kochsalz Mitochondrien beeinflusst.
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BIOspektrum 28
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June 2022
Bruton's tyrosine kinase inhibitors in multiple sclerosis: pioneering the path towards treatment of progression?
Geladaris, A., Torke, S. and Weber, M.S.
CNS drugs 36
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October 2022
Complement activation induces excessive T cell cytotoxicity in severe COVID-19.
Georg, P., Astaburuaga-García, R., Bonaguro, L., Brumhard, S., Michalick, L., Lippert, L.J., Kostevc, T., Gäbel, C., Schneider, M., Streitz, M., Demichev, V., Gemünd, I., Barone, M., Tober-Lau, P., Helbig, E.T., Hillus, D., Petrov, L., Stein, J., Dey, H.P., Paclik, D., Iwert, C., Mülleder, M., Aulakh, S.K., Djudjaj, S., Bülow, R.D., Mei, H.E., Schulz, A.R., Thiel, A., Hippenstiel, S., Saliba, A.E., Eils, R., Lehmann, I., Mall, M.A., Stricker, S., Röhmel, J., Corman, V.M., Beule, D., Wyler, E., Landthaler, M., Obermayer, B., von Stillfried, S., Boor, P., Demir, M., Wesselmann, H., Suttorp, N., Uhrig, A., Müller-Redetzky, H., Nattermann, J., Kuebler, W.M., Meisel, C., Ralser, M., Schultze, J.L., Aschenbrenner, A.C., Thibeault, C., Kurth, F., Sander, L.E., Blüthgen, N. and Sawitzki, B.
Cell 185
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3 February 2022
The role of intraspinal sensory neurons in the control of quadrupedal locomotion.
Gerstmann, K., Jurčić, N., Blasco, E., Kunz, S., de Almeida Sassi, F., Wanaverbecq, N. and Zampieri, N.
Current Biology 32
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6 June 2022
Improving robustness of automatic cardiac function quantification from cine magnetic resonance imaging using synthetic image data.
Gheorghiță, B.A., Itu, L.M., Sharma, P., Suciu, C., Wetzl, J., Geppert, C., Ali, M.A.A., Lee, A.M., Piechnik, S.K., Neubauer, S., Petersen, S.E., Schulz-Menger, J. and Chițiboi, T.
Scientific Reports 12
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14 February 2022
Isotopic tracing of glucose metabolites in human monocytes to assess changes in inflammatory conditions.
Giacomello, G., Böttcher, C. and Parr, M.K.
STAR Protocols 3
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16 December 2022
Structure-function correlates of vision loss in neuromyelitis optica spectrum disorders.
Gigengack, N.K., Oertel, F.C., Motamedi, S., Bereuter, C., Duchow, A., Rust, R., Bellmann‑Strobl, J., Ruprecht, K., Schmitz-Hübsch, T., Paul, F., Brandt, A.U. and Zimmermann, H.G.
Scientific Reports 12
(1): 17545.
20 October 2022
Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia.
Gilioli, D., Fusco, S., Tavella, T., Giannetti, K., Conti, A., Santoro, A., Carsana, E., Beretta, S., Schönlein, M., Gambacorta, V., Aletti, F.M., Carraba, M.G., Bonini, C., Ciceri, F., Merelli, I., Vago, L., Schmitt, C.A. and Di Micco, R.
bioRxiv
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17 November 2022
Aging-regulated TUG1 is dispensable for endothelial cell function.
Gimbel, A.T., Koziarek, S., Theodorou, K., Schulz, J.F., Stanicek, L., Kremer, V., Ali, T., Günther, S., Kumar, S., Jo, H., Hübner, N., Maegdefessel, L., Dimmeler, S., van Heesch, S. and Boon, R.A.
PLoS ONE 17
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29 September 2022
Rapid inflammasome activation is attenuated in post-myocardial infarction monocytes.
Giral, H., Franke, V., Moobed, M., Müller, M.F., Lübking, L., James, D.M., Hartung, J., Kuschnerus, K., Meteva, D., Seppelt, C., Jakob, P., Klingenberg, R., Kränkel, N., Leistner, D., Zeller, T., Blankenberg, S., Zimmermann, F., Haghikia, A., Lüscher, T.F., Akalin, A., Landmesser, U. and Kratzer, A.
Frontiers in Immunology 13
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26 April 2022
Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus.
Gjaltema, R.A.F., Schwämmle, T., Kautz, P., Robson, M., Schöpflin, R., Ravid Lustig, L., Brandenburg, L., Dunkel, I., Vechiatto, C., Ntini, E., Mutzel, V., Schmiedel, V., Marsico, A., Mundlos, S. and Schulz, E.G.
Molecular Cell 82
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6 January 2022
Deep learning-assisted peak curation for large-scale LC-MS metabolomics.
Gloaguen, Y., Kirwan, J.A. and Beule, D.
Analytical Chemistry 94
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29 March 2022
An unusual aspartic acid cluster in the reovirus attachment fiber s1 mediates stability at low pH and preserves trimeric organization.
Glorani, G., Ruwolt, M., Holton, N., Loll, B. and Neu, U.
Journal of Virology 96
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April 2022
Every islet matters: improving the impact of human islet research.
Gloyn, Anna L, Ibberson, Mark, Marchetti, Piero, Powers, Alvin C, Rorsman, Patrik, Sander, M. and Solimena, Michele
Nature Metabolism 4
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August 2022
Fluorescence spectroscopy of low-level endogenous β-adrenergic receptor expression at the plasma membrane of differentiating human iPSC-derived cardiomyocytes.
Gmach, P., Bathe-Peters, M., Telugu, N., Miller, D.C. and Annibale, P.
International Journal of Molecular Sciences 23
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8 September 2022
Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O., Zincke, F., Eckert, A., Kobelt, D., Preissner, S., Liebeskind, J.M., Gunkel, N., Putzker, K., Lewis, J., Preissner, S., Kortüm, B., Walther, W., Mura, K., Bourne, P.E., Stein, U. and Preissner, R.
Clinical and Translational Medicine 12
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20 February 2022
Expression of circ_Satb1 is decreased in mesial temporal lobe epilepsy and regulates dendritic spine morphology.
Gomes-Duarte, A., Venø, M.T., de Wit, M., Senthilkumar, K., Broekhoven, M.H., van den Herik, J., Heeres, F.R., van Rossum, D., Rybiczka-Tesulov, M., Legnini, I., van Rijen, P.C., van Eijsden, P., Gosselaar, P.H., Rajewsky, N., Kjems, J., Vangoor, V.R. and Pasterkamp, R.J.
Frontiers in Molecular Neuroscience 15
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3 March 2022
Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension.
Grabowski, K., Herlan, L., Witten, A., Qadri, F., Eisenreich, A., Lindner, D., Schädlich, M., Schulz, A., Subrova, J., Mhatre, K.N., Primessnig, U., Plehm, R., van Linthout, S., Escher, F., Bader, M., Stoll, M., Westermann, D., Heinzel, F.R. and Kreutz, R.
Hypertension Research 45
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January 2022
Preclinical testing of dendritic core-multishell nanoparticles in inflammatory skin equivalents.
Graff, P., Hönzke, S., Joshi, A.A., Yealland, G., Fleige, E., Unbehauen, M., Schäfer-Korting, M., Hocke, A., Haag, R. and Hedtrich, S.
Molecular Pharmaceutics 19
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6 June 2022
The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
Grasedieck, S., Cabantog, A., MacPhee, L., Im, J., Ruess, C., Demir, B., Sperb, N., Rücker, F.G., Döhner, K., Herold, T., Pollack, J.R., Bullinger, L., Rouhi, A. and Kuchenbauer, F.
Haematologica 107
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August 2022
Leveraging visual outcome measures to advance therapy development in neuroimmunologic disorders.
Graves, J.S., Oertel, F.C., Van der Walt, A., Collorone, S., Sotirchos, E.S., Pihl-Jensen, G., Albrecht, P., Yeh, E.A., Saidha, S., Frederiksen, J., Newsome, S.D. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 9
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March 2022
Age of red cells for transfusion and outcomes in patients with ARDS.
Graw, J.A., Bünger, V., Materne, L.A., Krannich, A., Balzer, F., Francis, R.C.E., Pruß, A., Spies, C.D., Kuebler, W.M., Weber-Carstens, S., Menk, M. and Hunsicker, O.
Journal of Clinical Medicine 11
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4 January 2022
Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.
Greco, T.M., Secker, C., Silva Ramos, E., Federspiel, J.D., Liu, J.P., Perez, A.M., Al-Ramahi, I., Cantle, J.P., Carroll, J.B., Botas, J., Zeitlin, S.O., Wanker, E.E. and Cristea, I.M.
Cell Systems 13
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22 April 2022
Was ist gesichert in der Therapie der chronischen Nierenerkrankung? [What is confirmed in the treatment of chronic kidney disease?].
Greite, R. and Schmidt-Ott, K.
Innere Medizin 63
(12): 237-1243.
December 2022
Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.
Grinat, J., Kosel, F., Goveas, N., Kranz, A., Alexopoulou, D., Rajewsky, K., Sigal, M., Stewart, A.F. and Heuberger, J.
Life Science Alliance 5
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April 2022
Influence of nanogel amphiphilicity on dermal delivery: balancing surface hydrophobicity and network rigidity.
Gruber, Al., Joshi, A.A., Graff, P., Cuéllar-Camacho, J.L., Hedtrich, S. and Klinger, D.
Biomacromolecules 23
(1): 112-127.
10 January 2022
Isolation of neoantigen-specific human T cell receptors from different human and murine repertoires.
Grunert, C., Willimsky, G., Peuker, C.A., Rhein, S., Hansmann, L., Blankenstein, T., Blanc, E., Beule, D., Keller, U., Pezzutto, A. and Busse, A.
Cancers 14
(7): 1842.
6 April 2022
Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients.
Grunow, J.J., Reiher, K., Carbon, N.M., Engelhardt, L.J., Mai, K., Koch, S., Schefold, J.C., Z'Graggen, W., Schaller, S.J., Fielitz, J., Spranger, J., Weber-Carstens, S. and Wollersheim, T.
Critical Care 26
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3 August 2022
Statins aggravate the risk of insulin resistance in human muscle.
Grunwald, S.A., Haafke, S., Grieben, U., Kassner, U., Steinhagen-Thiessen, E. and Spuler, S.
International Journal of Molecular Sciences 23
(4): 2398.
21 February 2022
Fast acquisition of left and right ventricular function parameters applying cardiovascular magnetic resonance in clinical routine - validation of a 2-shot compressed sensing cine sequence.
Gröschel, J., Ammann, C., Zange, L., Viezzer, D., Forman, C., Schmidt, M., Blaszczyk, E. and Schulz-Menger, J.
Scandinavian Cardiovascular Journal 56
(1): 266-275.
14 July 2022
Different impacts on the heart after COVID-19 infection and vaccination: insights from cardiovascular magnetic resonance.
Gröschel, J., Bhoyroo, Y., Blaszczyk, E., Trauzeddel, R.F., Viezzer, D., Saad, H., Fenski, M. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 9
: 916922.
14 July 2022
Stellenwert der kardiovaskulären Magnetresonanz in der kardiovaskulären Diagnostik [Role of cardiovascular magnetic resonance in cardiovascular diagnostics].
Gröschel, J., Trauzeddel, R.F., Blaszczyk, E. and Schulz-Menger, J.
Deutsche Medizinische Wochenschrift 147
(9): 528-537.
25 April 2022
Acute kidney injury in patients receiving pembrolizumab combination therapy versus pembrolizumab monotherapy for advanced lung cancer.
Gupta, S., Strohbehn, I.A., Wang, Q., Hanna, P.E., Seethapathy, R., Prosek, J.M., Herrmann, S.M., Abudayyeh, A., Malik, A.B., Loew, S., Carlos, C.A., Chang, W.T., Beckerman, P., Mithani, Z., Shah, C.V., Renaghan, A., de Seigneux, S., Campedel, L., Kitchlu, A., Shin, D.S., Coppock, G., Lumlertgul, N., Garcia, P., Ortiz-Melo, D.I., Rashidi, A., Sprangers, B., Aggarwal, V., Benesova, K., Jhaveri, K.D., Cortazar, F.B., Weins, A., Zuo, Y., Mooradian, M.J., Reynolds, K.L., Leaf, D.E. and Sise, M.E.
Kidney International 102
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October 2022
Cell-type specific inhibition controls the high-frequency oscillations in the medial entorhinal cortex.
Gurgenidze, S., Bäuerle, P., Schmitz, D., Vida, I., Gloveli, T. and Dugladze, T.
International Journal of Molecular Sciences 23
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15 November 2022
Phenotypic spectrum of BLM- and RMI1-related Bloom syndrome.
Gönenc, I.I., Elcioglu, N.H., Martinez Grijalva, C., Aras, S., Großmann, N., Praulich, I., Altmüller, J., Kaulfuß, S., Li, Y., Nürnberg, P., Burfeind, P., Yigit, G. and Wollnik, B.
Clinical Genetics 101
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May 2022
MACC1-dependent antitumor effect of curcumin in colorectal cancer.
Güllü, N., Smith, J., Herrmann, P. and Stein, U.
Nutrients 14
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12 November 2022
The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel, G., Conlon, T.M., Jeridi, A., Kim, R., Ertüz, Z., Lang, N.J., Ansari, M., Novikova, M., Jiang, D., Strunz, M., Gaianova, M., Hollauer, C., Gabriel, C., Angelidis, I., Doll, S., Pestoni, J.C., Edelmann, S.L., Kohlhepp, M.S., Guillot, A., Bassler, K., Van Eeckhoutte, H.P., Kayalar, Ö., Konyalilar, N., Kanashova, T., Rodius, S., Ballester-López, C., Genes Robles, C.M., Smirnova, N., Rehberg, M., Agarwal, C., Krikki, I., Piavaux, B., Verleden, S.E., Vanaudenaerde, B., Königshoff, M., Dittmar, G., Bracke, K.R., Schultze, J.L., Watz, H., Eickelberg, O., Stoeger, T., Burgstaller, G., Tacke, F., Heissmeyer, V., Rinkevich, Y., Bayram, H., Schiller, H.B., Conrad, M., Schneider, R. and Yildirim, A.Ö.
Nature Communications 13
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14 March 2022
A molecularly characterized preclinical platform of subcutaneous renal cell carcinoma (RCC) patient-derived xenograft models to evaluate novel treatment strategies.
Gürgen, D., Becker, M., Dahlmann, M., Flechsig, S., Schaeffeler, E., Büttner, F.A., Schmees, C., Bohnert, R., Bedke, J., Schwab, M., Wendler, J.J., Schostak, M., Jandrig, B., Walther, W. and Hoffmann, J.
Frontiers in Oncology 12
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21 June 2022
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Lösliche Guanylatzyklase(sGC)-Stimulation mit Vericiguat: Von der pharmakologischen Idee bis zur Therapie der chronischen Herzinsuffizienz [Soluble guanylate cyclase (sGC) stimulation with vericiguat : from the pharmacological idea to the treatment of chronic heart failure].
Haase, N., Kedziora, S.M., Mueller, D.N. and Dechend, R.
Kardiologie 16
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December 2022
Introduction of Lazy Luna an automatic software-driven multilevel comparison of ventricular function quantification in cardiovascular magnetic resonance imaging.
Hadler, T., Wetzl, J., Lange, S., Geppert, C., Fenski, M., Abazi, E., Gröschel, J., Ammann, C., Wenson, F., Töpper, A., Däuber, S. and Schulz-Menger, J.
Scientific Reports 12
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22 April 2022
Cytochrome P450 2D (CYP2D) enzyme dysfunction associated with aging and serotonin deficiency in the brain and liver of female Dark Agouti rats.
Haduch, A., Danek, P.J., Kuban, W., Pukło, R., Alenina, N., Gołębiowska, J., Popik, P., Bader, M. and Daniel, W.A.
Neurochemistry International 152
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January 2022
Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS).
Haffke, M., Freitag, H., Rudolf, G., Seifert, M., Doehner, W., Scherbakov, N., Hanitsch, L., Wittke, K., Bauer, S., Konietschke, F., Paul, F., Bellmann-Strobl, J., Kedor, C., Scheibenbogen, C. and Sotzny, F.
Journal of Translational Medicine 20
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22 March 2022
miR-142 favors naïve B cell residence in peripheral lymph nodes.
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An uncertainty-aware, shareable, and transparent neural network architecture for brain-age modeling.
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Refining AML treatment: the role of genetics in response and resistance evaluation to new agents.
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26 March 2022
Long-term connectome analysis reveals reshaping of visual, spatial networks in a model with vascular dementia features.
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A comparative study of graph matching algorithms in computer vision.
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Journal of the American Heart Association 11
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6 December 2022
A critical period of translational control during brain development at codon resolution.
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Sensitivity and specificity of loss of heterozygosity analysis for the classification of rare germline variants in BRCA1/2: results of the observational AGO-TR1 study (NCT02222883).
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Widely applicable, extended flow cytometric stem cell enumeration panel for quality control of advanced cellular products.
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Scientific Reports 12
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26 October 2022
Robust induction of primordial germ cells of white rhinoceros on the brink of extinction.
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Pseudocholinesterase as a biomarker for untreated Wilson's disease.
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Anti-SARS-CoV2 antibody-mediated cytokine release syndrome in a patient with acute promyelocytic leukemia.
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A phase II trial to evaluate the combination of pixantrone and obinutuzumab for patients with relapsed aggressive lymphoma: Final results of the prospective, multicentre GOAL trial.
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Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors.
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Microglia/macrophage derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model.
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3D model-based super-resolution motion-corrected cardiac T1 mapping.
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Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
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Fusion moves for graph matching.
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CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage.
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Physical performance and non-esterified fatty acids in men and women after transcatheter aortic valve implantation (TAVI).
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June 2022
15-keto-Prostaglandin E(2) exhibits bioactive role by modulating glomerular cytoarchitecture through EP2/EP4 receptors.
Kourpa, A., Kaiser-Graf, D., Sporbert, A., Philippe, A., Catar, R., Rothe, M., Mangelsen, E., Schulz, A., Bolbrinker, J., Kreutz, R. and Panáková, D.
Life Sciences 310
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1 December 2022
Computational approaches to predicting treatment response to obesity using neuroimaging.
Kozarzewski, L., Maurer, L., Mähler, A., Spranger, J. and Weygandt, M.
Reviews in Endocrine & Metabolic Disorders 23
(4): 773–805.
August 2022
Reduced splenic uptake on (68)Ga-Pentixafor-PET/CT imaging in multiple myeloma - a potential imaging biomarker for disease prognosis.
Kraus, S., Klassen, P., Kircher, M., Dierks, A., Habringer, S., Gäble, A., Kortüm, K.M., Weinhold, N., Ademaj-Kospiri, V., Werner, R.A., Schirbel, A., Buck, A.K., Herhaus, P., Wester, H.J., Rosenwald, A., Weber, W.A., Einsele, H., Keller, U., Rasche, L. and Lapa, C.
Theranostics 12
(13): 5986-5994.
8 August 2022
A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse.
Krause, F., Mohebian, K., Delpero, M., Hesse, D., Kuehn, R., Arends, D. and Brockmann, G.A.
Mammalian Genome 33
(3): 465–470.
September 2022
Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society.
Kroke, A., Schmidt, A., Amini, A.M., Kalotai, N., Lehmann, A., Haardt, J., Bauer, J.M., Bischoff-Ferrari, H.A., Boeing, H., Egert, S., Ellinger, S., Kühn, T., Louis, S., Lorkowski, S., Nimptsch, K., Remer, T., Schulze, M.B., Siener, R., Stangl, G.I., Volkert, D., Zittermann, A., Buyken, A.E., Watzl, B. and Schwingshackl, L.
European Journal of Nutrition 61
(4): 2091-2101.
June 2022
Overnight unilateral withdrawal of thalamic deep brain stimulation to identify reversibility of gait disturbances.
Kroneberg, D., Al-Fatly, B., Schmitz-Hübsch, T., Gandor, F., Gruber, D., Ebersbach, G., Horn, A. and Kühn, A.A.
Experimental Neurology 355
: 114135.
September 2022
Editorial: Sexual dimorphism in biomedical research and its therapeutic implications.
Kroon, J., Mahmoodzadeh, S. and Helsen, C.
Frontiers in Endocrinology 13
: 1009712.
19 August 2022
GMP-grade manufacturing and quality control of a non-virally engineered advanced therapy medicinal product for personalized treatment of age-related macular degeneration.
Kropp, M., Harmening, N., Bascuas, T., Johnen, S., De Clerck, E., Fernández, V., Ronchetti, M., Cadossi, R., Zanini, C., Scherman, D., Ivics, Z., Marie, C., Izsvák, Z. and Thumann, G.
Biomedicines 10
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November 2022
Time for change in research careers: Are we as research organizations doing everything we can for postdocs?
Krull, S., Silva, A.A., Afanasyeva, D., Christensen, S. and Agostinho, M.
EMBO Reports 23
(2): e54260.
3 February 2022
Paracrine interleukin 6 induces cerebral remodeling at early stages after unilateral common carotid artery occlusion in mice.
Kuffner, M.T.C., Koch, S.P, Kirchner, M., Mueller, S., Lips, J., An, J., Mertins, P., Dirnagl, U., Endres, M., Boehm-Sturm, P., Harms, C. and Hoffmann, C.J.
Frontiers in Cardiovascular Medicine 8
: 805095.
27 January 2022
Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses.
Kunath, B.J., Hickl, O., Queirós, P., Martin-Gallausiaux, C., Lebrun, L.A., Halder, R., Laczny, C.C., Schmidt, T.S.B., Hayward, M.R., Becher, D., Heintz-Buschart, A., de Beaufort, C., Bork, P., May, P. and Wilmes, P.
Microbiome 10
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28 December 2022
Small cell lung cancer stem cells display mesenchymal properties and exploit immune checkpoint pathways in activated cytotoxic T lymphocytes.
Kursunel, M.A., Taskiran, E.Z., Tavukcuoglu, E., Yanik, H., Demirag, F., Karaosmanoglu, B., Ozbay, F.G., Uner, A., Esendagli, D., Kizilgoz, D., Yilmaz, U. and Esendagli, G.
Cancer Immunology Immunotherapy 71
(2): 445-459.
February 2022
Statistical analysis in the German National Cohort (NAKO) - specific aspects and general recommendations.
Kuss, O., Becher, H., Wienke, A., Ittermann, T., Ostrzinski, S., Schipf, S., Schmidt, C.O., Leitzmann, M., Pischon, T., Krist, L., Roll, S., Sand, M., Pohlabeln, H., Rach, S., Jöckel, K.H., Stang, A., Mueller, U.A., Werdecker, A., Westerman, R., Greiser, K.H. and Michels, K.B.
European Journal of Epidemiology 37
(4): 429-436.
April 2022
The gut microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS).
König, R.S., Albrich, W.C., Kahlert, C.R., Bahr, L.S., Löber, U., Vernazza, P., Scheibenbogen, C. and Forslund, S.K.
Frontiers in Immunology 12
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3 January 2022
Genome engineering in rodents - status quo and perspectives.
Kühn, R.
Laboratory Animals 56
(1): 83-87.
1 February 2022
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Magnetic field-induced interactions between phones containing magnets and cardiovascular implantable electronic devices: Flip it to be safe?
Lacour, P., Dang, P.L., Heinzel, F.R., Parwani, A.S., Bähr, F., Kucher, A., Hohendanner, F., Niendorf, T., Rahimi, F., Saha, N., Han, H., Rubarth, K., Sherif, M., Boldt, L.H., Pieske, B. and Blaschke, F.
Heart Rhythm 19
(3): 372-380.
March 2022
Interleukin 8 in postoperative delirium - preliminary findings from two studies.
Lammers-Lietz, F., Akyuz, L., Feinkohl, I., Lachmann, C., Pischon, T., Volk, H.D., von Häfen, C., Yürek, F., Winterer, G. and Spies, C.D.
Brain Behavior & Immunity - Health 20
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March 2022
Rapid single-cell identification of Epstein-Barr virus-specific T-cell receptors for cellular therapy.
Lammoglia Cobo, M.F., Welters, C., Rosenberger, L., Leisegang, M., Dietze, K., Pircher, C., Penter, L., Gary, R., Bullinger, L., Takvorian, A., Moosmann, A., Dornmair, K., Blankenstein, T., Kammertöns, T., Gerbitz, A. and Hansmann, L.
Cytotherapy 24
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August 2022
The evolutionary dynamics of extrachromosomal DNA in human cancers.
Lange, J.T., Rose, J.C., Chen, C.Y., Pichugin, Y., Xie, L., Tang, J., Hung, K.L., Yost, K.E., Shi, Q., Erb, M.L., Rajkumar, U., Wu, S., Taschner-Mandl, S., Bernkopf, M., Swanton, C., Liu, Z., Huang, W., Chang, H.Y., Bafna, V., Henssen, A.G., Werner, B. and Mischel, P.S.
Nature Genetics 54
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October 2022
A flexible tool to correct superimposed mass isotopologue distributions in GC-APCI-MS flux experiments.
Langenhan, J., Jaeger, C., Baum, K., Simon, M. and Lisec, J.
Metabolites 12
(5): 408.
29 April 2022
Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling.
Langer, H.T., West, D., Senden, J., Spuler, S., van Loon, L.J.C. and Baar, K.
Scientific Reports 12
(1): 7553.
9 May 2022
Sox9 is required for nail bed differentiation and digit tip regeneration.
Lao, M., Hurtado, A., de Castro, A.C., Burgos, M., Jiménez, R. and Barrionuevo, F.J.
Journal of Investigative Dermatology 142
(10): 2613-2622.
October 2022
Editorial: Lineage tracing, hematopoietic stem cell and immune cell dynamics.
Lareau, C.A., Romagnani, C. and Ludwig, L.S.
Frontiers in Immunology 13
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18 October 2022
Efficient CRISPR/Cas9-mediated mutagenesis in primary human B cells for identifying plasma cell regulators.
Le, T.A., Chu, V.T., Lino, A.C., Schrezenmeier, E., Kressler, C., Hamo, D., Rajewsky, K., Dörner, T. and Dang, V.D.
Molecular Therapy - Nucleic Acids 30
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13 December 2022
Different classes of genomic inserts contribute to human antibody diversity.
Lebedin, M., Foglierini, M., Khorkova, S., Vázquez García, C., Ratswohl, C., Davydov, A.N., Turchaninova, M.A., Daubenberger, C., Chudakov, D.M., Lanzavecchia, A. and de la Rosa, K.
Proceedings of the National Academy of Sciences of the United States of America 119
(36): e2205470119.
6 September 2022
Heteroplasmy of wild type mitochondrial DNA variants in mice causes metabolic heart disease with pulmonary hypertension and frailty.
Lechuga-Vieco, A.V., Latorre-Pellicer, A., Calvo, E., Torroja, C., Pellico, J., Acín-Pérez, R., García-Gil, M.L., Santos, A., Bagwan, N., Bonzon-Kulichenko, E., Magni, R., Benito, M., Justo-Méndez, R., Simon, A.K., Sánchez-Cabo, F., Vázquez, J., Ruíz-Cabello, J. and Enríquez, J.A.
Circulation 145
(12): 1084-1101.
5 April 2022
Mafa-dependent GABAergic activity promotes mouse neonatal apneas.
Lecoin, L., Dempsey, B., Garancher, A., Bourane, S., Ruffault, P.L., Morin-Surun, M.P., Rocques, N., Goulding, M., Eychène, A., Pouponnot, C., Fortin, G. and Champagnat, J.
Nature Communications 13
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7 June 2022
B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice.
Lee, M.S.J., Inoue, T., Ise, W., Matsuo-Dapaah, J., Wing, J.B., Temizoz, B., Kobiyama, K., Hayashi, T., Patil, A., Sakaguchi, S., Simon, A.K., Bezbradica, J.S., Nagatoishi, S., Tsumoto, K., Inoue, J.I., Akira, S., Kurosaki, T., Ishii, K.J. and Coban, C.
Journal of Experimental Medicine 219
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7 February 2022
Alport syndrome and autosomal dominant tubulointerstitial kidney disease frequently underlie end stage renal disease of unknown origin - a single center analysis.
Leenen, E., Erger, F., Altmüller, J., Wenzel, A., Thiele, H., Harth, A., Tschernoster, N., Lokhande, S., Joerres, A., Becker, J.U., Ekici, A., Huettel, B., Beck, B. and Weidemann, A.
Nephrology Dialysis Transplantation 37
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22 September 2022
Spatio-temporal, optogenetic control of gene expression in organoids.
Legnini, I., Emmenegger, L., Zappulo, A., Wurmus, R., Oliveras Martinez, A., Cerda Jara, C., Boltengagen, A., Hessler, T., Mastrobuoni, G., Rybak-Wolf, A., Kempa, S., Zinzen, R.P., Woehler, A. and Rajewsky, N.
bioRxiv
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9 February 2022
Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Leng, H., Zhang, H., Li, L., Zhang, S., Wang, Y., Chavda, S.J., Galas-Filipowicz, D., Lou, H., Ersek, A., Morris, E.V., Sezgin, E., Lee, Y.H., Li, Y., Lechuga-Vieco, A.V., Tian, M., Mi, J.Q., Yong, K., Zhong, Q., Edwards, C.M., Simon, A.K. and Horwood, N.J.
Nature Communications 13
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22 December 2022
A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies.
Lessel, D., Rading, K., Campbell, S.E., Thiele, H., Altmüller, J., Gordon, L.B. and Kubisch, C.
American Journal of Medical Genetics A 188
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January 2022
Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.
Letizia, M., Wang, Y.H., Kaufmann, U., Gerbeth, L., Sand, A., Brunkhorst, M., Weidner, P., Ziegler, J.F., Böttcher, C., Schlickeiser, S., Fernández, C., Yamashita, M., Stauderman, K., Sun, K., Kunkel, D., Prakriya, M., Sanders, A.D., Siegmund, B., Feske, S. and Weidinger, C.
EMBO Molecular Medicine
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2 August 2022
Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors.
Li, C., Wang, H., Gil, S., Germond, A., Fountain, C., Baldessari, A., Kim, J., Liu, Z., Georgakopoulou, A., Radtke, S., Raskó, T., Pande, A., Chiang, C., Chin, E., Yannaki, E., Izsvak, Z., Papayannopoulou, T., Kiem, H.P. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 24
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10 March 2022
Fly Cell Atlas: a single-nucleus transcriptomic atlas of the adult fruit fly.
Li, H., Janssens, J., De Waegeneer, M., Kolluru, S.S., Davie, K., Gardeux, V., Saelens, W., David, F.P.A., Brbić, M., Spanier, K., Leskovec, J., McLaughlin, C.N., Xie, Q., Jones, R.C., Brueckner, K., Shim, J., Tattikota, S.G., Schnorrer, F., Rust, K., Nystul, T.G., Carvalho-Santos, Zi., Ribeiro, C., Pal, S., Mahadevaraju, S., Przytycka, T.M., Allen, A.M., Goodwin, S.F., Berry, C.W., Fuller, M.T., White-Cooper, H., Matunis, E.L., DiNardo, S., Galenza, A., O'Brien, L.E., Dow, J.A.T., Jasper, H., Oliver, B., Perrimon, N., Deplancke, B., Quake, S.R., Luo, L. and Aerts, S.
Science 375
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4 March 2022
Introducing the Molecular Pharmaceutics special issue on “tiny things, big impact: nanomedicine in Canada”.
Li, S.D., Wasan, E., Bally, M. and Hedtrich, S.
Molecular Pharmaceutics 19
(6): 1657-1658.
6 June 2022
Stem cells, helicobacter pylori and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer.
Liabeuf, D., Oshima, M., Stange, D.E. and Sigal, M.
Gastroenterology 162
(4): 1067-1087.
April 2022
High-content analysis of neuronal morphology in human iPSC-derived neurons.
Lickfett, S., Menacho, C., Zink, A., Telugu, N.S., Beller, M., Diecke, S., Cambridge, S. and Prigione, A.
STAR Protocols 3
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16 September 2022
Mako: a graph-based pattern growth approach to detect complex structural variants.
Lin, J., Yang, X., Kosters, W., Xu, T., Jia, Y., Wang, S., Zhu, Q., Ryan, M., Guo, L., Zhang, C., Lee, C., Devine, S.E., Eichler, E.E. and Ye, K.
Genomics, Proteomics and Bioinformatics 20
(1): 205-218.
February 2022
Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function.
Lin, S.J., Vona, B., Porter, H.M., Izadi, M., Huang, K., Lacassie, Y., Rosenfeld, J.A., Khan, S., Petree, C., Ali, T.A., Muhammad, N., Khan, S.A., Muhammad, N., Liu, P., Haymon, M.L., Rüschendorf, F., Kong, I.K., Schnapp, L., Shur, N., Chorich, L., Layman, L., Haaf, T., Pourkarimi, E., Kim, H.G. and Varshney, G.K.
Human Mutation 43
(10): 1472-1489.
October 2022
Neuroophthalmologische Präsentation der Retrobulbärneuritis im Rahmen der Myelin-Oligodendrozyten-Glykoprotein-Antikörper-assoziierten Erkrankung [Neuro-ophthalmological presentation of optic neuritis in myelin oligodendrocyte glycoprotein antibody-associated disease].
Lin, T.Y., Asseyer, S., Buenrostro, G.S., Feldmann, K., Hamann, S., Paul, F. and Zimmermann, H.G.
Klinische Monatsblatter fur Augenheilkunde 239
(11): 1305-1314.
21 November 2022
Serum glial fibrillary acidic protein correlates with retinal structural damage in aquaporin-4 antibody positive neuromyelitis optica spectrum disorder.
Lin, T.Y., Schindler, P., Grittner, U., Oertel, F.C., Lu, A., Motamedi, S., Yadav, S.K., Duchow, A.S., Jarius, S., Kuhle, J., Benkert, P., Brandt, A.U., Bellmann-Strobl, J., Schmitz-Hübsch, T., Paul, F., Ruprecht, K. and Zimmermann, H.G.
Multiple Sclerosis and Related Disorders 67
: 104100.
November 2022
HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin, Y.H., Major, J.L., Liebner, T., Hourani, Z., Travers, J.G., Wennersten, S.A., Haefner, K.R., Cavasin, M.A., Wilson, C.E., Jeong, M.Y., Han, Y., Gotthardt, M., Ferguson, S.K., Ambardekar, A.V., Lam, M.P., Choudhary, C., Granzier, H.L., Woulfe, K.C. and McKinsey, T.A.
Journal of Clinical Investigation 132
(10): e148333.
16 May 2022
Diffusion-weighted magnetic resonance imaging in rat kidney using two-dimensional navigated, interleaved echo-planar imaging at 7.0 T.
Liu, Q., Xu, Z., Zhao, K., Hoge, W.S., Zhang, X., Mei, Y., Lu, Q., Niendorf, T. and Feng, Y.
NMR in Biomedicine 35
(5): e4652.
May 2022
Hemodialysis and biotransformation of erythrocyte epoxy fatty acids in peripheral tissue.
Liu, T., Dogan, I., Rothe, M., Kunz, J.V., Knauf, F., Gollasch, M., Luft, F.C. and Gollasch, B.
Prostaglandins, Leukotrienes, and Essential Fatty Acids 181
: 102453.
June 2022
Hemodialysis and plasma oxylipin biotransformation in peripheral tissue.
Liu, T., Dogan, I., Rothe, M., Kunz, J.V., Knauf, F., Gollasch, M., Luft, F.C. and Gollasch, B.
Metabolites 12
(1): 34.
4 January 2022
Bioaccumulation of blood long-chain fatty acids during hemodialysis.
Liu, T., Dogan, I., Rothe, M., Reichardt, J., Knauf, F., Gollasch, M., Luft, F.C. and Gollasch, B.
Metabolites 12
(3): 269.
21 March 2022
Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo, W.T., Zhang, Y., Vadas, O., Roske, Y., Gulluni, F., De Santis, M.C., Zagar, A.V., Stephanowitz, H., Hirsch, E., Liu, F., Daumke, O., Kudryashev, M. and Haucke, V.
Nature Structural & Molecular Biology 29
(3): 218-228.
March 2022
Targeted analysis of cell-free circulating tumor DNA is suitable for early relapse and actionable target detection in patients with neuroblastoma.
Lodrini, M., Graef, J., Thole-Kliesch, T.M., Astrahantseff, K., Sprüssel, A., Grimaldi, M., Peitz, C., Linke, R.B., Hollander, J.F., Lankes, E., Künkele, A., Oevermann, L., Schwabe, G., Fuchs, J., Szymansky, A., Schulte, J.H., Hundsdoerfer, P., Eckert, C., Amthauer, H., Eggert, A. and Deubzer, H.E.
Clinical Cancer Research 28
(9): 1809-1820.
1 May 2022
Circulating cell-free DNA assessment in biofluids from children with neuroblastoma demonstrates feasibility and potential for minimally invasive molecular diagnostics.
Lodrini, M., Wünschel, J., Thole-Kliesch, T.M., Grimaldi, M., Sprüssel, A., Linke, R.B., Hollander, J.F., Tiburtius, D., Künkele, A., Schulte, J.H., Lankes, E., Elgeti, T., Hundsdörfer, P., Astrahantseff, K., Simon, T., Eggert, A. and Deubzer, H.E.
Cancers 14
(9): 2080.
21 April 2022
Fibrin-targeting molecular MRI in inflammatory CNS disorders.
Lohmeier, J., Silva, R.V., Tietze, A., Taupitz, M., Kaneko, T., Prüss, H., Paul, F., Infante-Duarte, C., Hamm, B., Caravan, P. and Makowski, M.R.
European Journal of Nuclear Medicine and Molecular Imaging 49
(11): 3692–3704.
September 2022
Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.
Lorenz, C., Zink, A., Henke, M.T., Staege, S., Mlody, B., Bünning, M., Wanker, E., Diecke, S., Schuelke, M. and Prigione, A.
Stem Cell Research 61
: 102742.
May 2022
Regulation of early cerebellar development.
Lowenstein, E., Cui, K. and Hernandez-Miranda, L.R.
FEBS Journal 290
(11): 2786-2804.
June 2022
Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders.
Lu, A., Zimmermann, H.G., Specovius, S., Motamedi, S., Chien, C., Bereuter, C., Lana-Peixoto, M.A., Fontenelle, M.A., Ashtari, F., Kafieh, R., Dehghani, A., Pourazizi, M., Pandit, L., D'Cunha, A., Kim, H.J., Hyun, J.W., Jung, S.K., Leocani, L., Pisa, M., Radaelli, M., Siritho, S., May, E.F., Tongco, C., De Sèze, J., Senger, T., Palace, J., Roca-Fernández, A., Leite, M.I., Sharma, S.M., Stiebel-Kalish, H., Asgari, N., Soelberg, K.K., Martinez-Lapiscina, E.H., Havla, J., Mao-Draayer, Y., Rimler, Z., Reid, A., Marignier, R., Cobo-Calvo, A., Altintas, A., Tanriverdi, U., Yildirim, R., Aktas, O., Ringelstein, M., Albrecht, P., Tavares, I.M., Bichuetti, D.B., Jacob, A., Huda, S., Soto de Castillo, I., Petzold, A., Green, A.J., Yeaman, M.R., Smith, T.J., Cook, L., Paul, F., Brandt, A.U. and Oertel, F.C.
Journal of Neurology Neurosurgery and Psychiatry 93
(2): 188-195.
February 2022
Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1.
Ludwig, L.S., Lareau, C.A., Bao, E.L., Liu, N., Utsugisawa, T., Tseng, A.M., Myers, S.A., Verboon, J.M., Ulirsch, J.C., Luo, W., Muus, C., Fiorini, C., Olive, M.E., Vockley, C.M., Munschauer, M., Hunter, A., Ogura, H., Yamamoto, T., Inada, H., Nakagawa, S., Ozono, S., Subramanian, V., Chiarle, R., Glader, B., Carr, S.A., Aryee, M.J., Kundaje, A., Orkin, S., Regev, A., McCavit, T., Kanno, H. and Sankaran, V.G.
Blood 139
(16): 2534-2546.
21 April 2022
Epigenetic "transgenerational" inheritance.
Luft, F.C.
Circulation 146
(14): 1096-1098.
4 October 2022
Translating plasma sodium, stores, and hydration state from mouse to man.
Luft, F.C.
European Heart Journal 43
(35): 3349-3351.
14 September 2022
Amiloride and calciuria.
Luft, F.C. and Sällström, J.
Nephrology Dialysis Transplantation 37
(2): 205-207.
February 2022
AntiSplodge: a neural-network-based RNA-profile deconvolution pipeline designed for spatial transcriptomics.
Lund, J.B., Lindberg, E.L., Maatz, H., Pottbaecker, F., Hübner, N. and Lippert, C.
NAR Genomics and Bioinformatics 4
(4): lqac073.
December 2022
LRFN5 locus structure is associated with autism and influenced by the sex of the individual and locus conversions.
Lybaek, H., Robson, M., de Leeuw, N., Hehir-Kwa, J.Y., Jeffries, A., Haukanes, B.I., Berland, S., de Bruijn, D., Mundlos, S., Spielmann, M. and Houge, G.
Autism research 15
(3): 421-433.
16 March 2022
Tongue immune compartment analysis reveals spatial macrophage heterogeneity.
Lyras, E.M., Zimmermann, K., Wagner, L.K., Dörr, D., Klose, C.S.N, Fischer, C., Jung, S., Yona, S., Hovav, A.H., Stenzel, W., Dommerich, S., Conrad, T., Leutz, A. and Mildner, A.
eLife 11
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24 June 2022
Renal deletion of LRRC8/VRAC channels induces proximal tubulopathy.
López-Cayuqueo, K.I., Planells-Cases, R., Pietzke, M., Oliveras, A., Kempa, S., Bachmann, S. and Jentsch, T.J.
Journal of the American Society of Nephrology 33
(8): 1528-1545.
August 2022
M
Impact of metabolic stress induced by diets, aging and fasting on tissue oxygen consumption.
Mackert, O., Wirth, E.K., Sun, R., Winkler, J., Liu, A., Renko, K., Kunz, S., Spranger, J. and Brachs, S.
Molecular Metabolism 64
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October 2022
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Mahajan, A., Spracklen, C.N., Zhang, W., Ng, M.C.Y., Petty, L.E., Kitajima, H., Yu, G.Z., Rüeger, S., Speidel, L., Kim, Y.J., Horikoshi, M., Mercader, J.M., Taliun, D., Moon, S., Kwak, S.H., Robertson, N.R., Rayner, N.W., Loh, M., Kim, B.J., Chiou, J., Miguel-Escalada, I., Della Briotta Parolo, P., Lin, K., Bragg, F., Preuss, M.H., Takeuchi, F., Nano, J., Guo, X., Lamri, A., Nakatochi, M., Scott, R.A., Lee, J.., Huerta-Chagoya, A., Graff, M., Chai, J.F., Parra, E.J., Yao, J., Bielak, L.F., Tabara, Y., Hai, Y., Steinthorsdottir, V., Cook, J.P., Kals, M., Grarup, N., Schmidt, E.M., Pan, I., Sofer, T., Wuttke, M., Sarnowski, C., Gieger, C., Nousome, D., Trompet, S., Long, J., Sun, M., Tong, L., Chen, W.M., Ahmad, M., Noordam, R., Lim, V.J.Y., Tam, C.H.T., Joo, Y.Y., Chen, C.H., Raffield, L.M., Lecoeur, C., Prins, B.P., Nicolas, A., Yanek, L.R., Chen, G., Jensen, R.A., Tajuddin, S., Kabagambe, E.K., An, P., Xiang, A.H., Choi, H.S., Cade, B.E., Tan, J., Flanagan, J., Abaitua, F., Adair, L.S., Adeyemo, A., Aguilar-Salinas, C.A., Akiyama, M., Anand, S.S., Bertoni, A., Bian, Z., Bork-Jensen, J., Brandslund, I., Brody, J.A., Brummett, C.M., Buchanan, T.A., Canouil, M., Chan, J.C.N., Chang, L.C., Chee, M.L., Chen, J., Chen, S.H., Chen, Y.T., Chen, Z., Chuang, L.M., Cushman, M., Das, S.K., de Silva, H.J., Dedoussis, G., Dimitrov, L., Doumatey, A.P., Du, S., Duan, Q., Eckardt, K.U., Emery, L.S., Evans, D.S., Evans, M.K., Fischer, K., Floyd, J.S., Ford, I., Fornage, M., Franco, O.H., Frayling, T.M., Freedman, B.I., Fuchsberger, C., Genter, P., Gerstein, H.C., Giedraitis, V., González-Villalpando, C., González-Villalpando, M.E., Goodarzi, M.O., Gordon-Larsen, P., Gorkin, D., Gross, M., Guo, Y., Hackinger, S., Han, S., Hattersley, A.T., Herder, C., Howard, A.G., Hsueh, W., Huang, M., Huang, W., Hung, Y.J., Hwang, M.Y., Hwu, C.M., Ichihara, S., Ikram, M.A., Ingelsson, M., Islam, M.T., Isono, M., Jang, H.M., Jasmine, F., Jiang, G., Jonas, J.B., Jørgensen, M.E., Jørgensen, T., Kamatani, Y., Kandeel, F.R., Kasturiratne, A., Katsuya, T., Kaur, V., Kawaguchi, T., Keaton, J.M., Kho, A.N., Khor, C.C., Kibriya, M.G., Kim, D.H., Kohara, K., Kriebel, J., Kronenberg, F., Kuusisto, J., Läll, K., Lange, L.A., Lee, M.S., Lee, N.R., Leong, A., Li, L., Li, Y., Li-Gao, R., Ligthart, S., Lindgren, C.M., Linneberg, A., Liu, C.T., Liu, J., Locke, A.E., Louie, T., Luan, J., Luk, A.O., Luo, X., Lv, J., Lyssenko, V., Mamakou, V., Mani, K.R., Meitinger, T., Metspalu, A., Morris, A.D., Nadkarni, G.N., Nadler, J.L., Nalls, M.A., Nayak, U., Nongmaithem, S.S., Ntalla, I., Okada, Y., Orozco, L., Patel, S.R., Pereira, M.A., Peters, A., Pirie, F.J., Porneala, B., Prasad, G., Preissl, S., Rasmussen-Torvik, L.J., Reiner, A.P., Roden, M., Rohde, R., Roll, K., Sabanayagam, C., Sander, M., Sandow, K., Sattar, N., Schönherr, S., Schurmann, C., Shahriar, M., Shi, J., Shin, D.M., Shriner, D., Smith, J.A., So, W.Y., Stančáková, A., Stilp, A.M., Strauch, K., Suzuki, K., Takahashi, A., Taylor, K.D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tomlinson, B., Torres, J.M., Tsai, F.J., Tuomilehto, J., Tusie-Luna, T., Udler, M.S., Valladares-Salgado, A., van Dam, R.M., van Klinken, J.B., Varma, R., Vujkovic, M., Wacher-Rodarte, N., Wheeler, E., Whitsel, E.A., Wickremasinghe, A.R., van Dijk, K.W., Witte, D.R., Yajnik, C.S., Yamamoto, K., Yamauchi, T., Yengo, L., Yoon, K., Yu, C., Yuan, J.M., Yusuf, S., Zhang, L., Zheng, W., Raffel, L.J., Igase, M., Ipp, E., Redline, S., Cho, Y.S., Lind, L., Province, M.A., Hanis, C.L., Peyser, P.A., Ingelsson, E., Zonderman, A.B., Psaty, B.M., Wang, Y.X., Rotimi, C.N., Becker, D.M., Matsuda, F., Liu, Y., Zeggini, E., Yokota, M., Rich, S.S., Kooperberg, C., Pankow, J.S., Engert, J.C., Chen, Y.D.I., Froguel, P., Wilson, J.G., Sheu, W.H.H., Kardia, S.L.R., Wu, J.Y., Hayes, M.G., Ma, R.C.W., Wong, T.Y., Groop, L., Mook-Kanamori, D.O., Chandak, G.R., Collins, F.S., Bharadwaj, D., Paré, G., Sale, M.M., Ahsan, H., Motala, A.A., Shu, X.O., Park, K.S., Jukema, J.W., Cruz, M., McKean-Cowdin, R., Grallert, H., Cheng, C.Y., Bottinger, E.P., Dehghan, A., Tai, E.S., Dupuis, J., Kato, N., Laakso, M., Köttgen, A., Koh, W.P., Palmer, C.N A., Liu, S., Abecasis, G., Kooner, J.S., Loos, R.J.F., North, K.E., Haiman, C.A., Florez, J.C., Saleheen, D., Hansen, T., Pedersen, O., Mägi, R., Langenberg, C., Wareham, N.J., Maeda, S., Kadowaki, T., Lee, J., Millwood, I.Y., Walters, R.G., Stefansson, K., Myers, S.R., Ferrer, J., Gaulton, K.J., Meigs, J.B., Mohlke, K.L., Gloyn, A.L., Bowden, D.W., Below, J.E., Chambers, J.C., Sim, X., Boehnke, M., Rotter, J.I., McCarthy, M.I. and Morris, A.P.
Nature Genetics 54
(5): 560-572.
May 2022
SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.
Maharana, S., Kretschmer, S., Hunger, S., Yan, X., Kuster, D., Traikov, S., Zillinger, T., Gentzel, M., Elangovan, S., Dasgupta, P., Chappidi, N., Lucas, N., Maser, K.I., Maatz, H., Rapp, A., Marchand, V., Chang, Y.T., Motorin, Y., Hubner, N., Hartmann, G., Hyman, A.A., Alberti, S. and Lee-Kirsch, M.A.
Molecular Cell 82
(19): 3712-3728.e10.
6 October 2022
Skin sodium accumulates in psoriasis and reflects disease severity.
Maifeld, A., Wild, J., Karlsen, T.V., Rakova, N., Wistorf, E., Linz, P., Jung, R., Birukov, A., Gimenez-Rivera, V.A., Wilck, N., Bartolomaeus, T., Dechend, R., Kleinewietfeld, M., Forslund, S.K., Krause, A., Kokolakis, G., Philipp, S., Clausen, B.E., Brand, A., Waisman, A., Kurschus, F.C., Wegner, J., Schultheis, M., Luft, F.C., Boschmann, M., Kelm, M., Wiig, H., Kuehne, T., Müller, D.N., Karbach, S. and Markó, L.
Journal of Investigative Dermatology 142
(1): 166-178.
January 2022
Loss of endothelial cytochrome P450 reductase induces vascular dysfunction in mice.
Malacarne, P.F., Ratiu, C., Gajos-Draus, A., Müller, N., Lopez, M., Pflüger-Müller, B., Ding, X., Warwick, T., Oo, J., Siragusa, M., Angioni, C., Günther, S., Weigert, A., Geißlinger, G., Lütjohann, D., Schunck, W.H., Fleming, I., Brandes, R.P. and Rezende, F.
Hypertension 79
(6): 1216-1226.
June 2022
Imaging and analysis of neuronal mitochondria in murine acute brain slices.
Malla, B., Hauser, A., Niesner, R. and Infante-Duarte, C.
Journal of Neuroscience Methods 372
: 109558.
15 April 2022
Teriflunomide preserves neuronal activity and protects mitochondria in brain slices exposed to oxidative stress.
Malla, B., Liotta, A., Bros, H., Ulshöfer, R., Paul, F., Hauser, A.E., Niesner, R. and Infante-Duarte, C.
International Journal of Molecular Sciences 23
(3): 1538.
28 January 2022
Forebrain development - an intricate balance decides between health and disease.
Mamo, T.M. and Hammes, A.
Neuroforum 28
(4): 233-243.
25 November 2022
Satellite glia of the adult dorsal root ganglia harbor stem cells that yield glia under physiological conditions and neurons in response to injury.
Maniglier, M., Vidal, M., Bachelin, Corinne, Deboux, C., Chazot, J., Garcia-Diaz, B. and Baron-Van Evercooren, A.
Stem Cell Reports 17
(11): 2467-2483.
8 November 2022
The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation towards the kidney lineage.
Mansour, F., Hinze, C., Telugu, N.S., Kresoja, J., Shaheed, I.B., Mosimann, C., Diecke, S. and Schmidt-Ott, K.M.
eLife 11
: e80165.
12 October 2022
In vitro Kinase-to-Phosphosite database (iKiP-DB) predicts kinase activity in phosphoproteomic datasets.
Mari, T., Mösbauer, K., Wyler, E., Landthaler, M., Drosten, C. and Selbach, M.
Journal of Proteome Research 21
(6): 1575-1587.
3 June 2022
AQP4-IgG-seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder.
Marignier, R., Pittock, S.J., Paul, F., Kim, H.J., Bennett, J. L., Weinshenker, B.G., Wingerchuk, D.M., Green, A.J., Fujihara, K., Cutter, G., Aktas, O., Hartung, H.P., Drappa, J., Ratchford, J.N., She, D., Smith, M., Rees, W., Cimbora, D., Katz, E. and Cree, B.A.C.
Multiple Sclerosis and Related Disorders 57
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January 2022
Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F., Jerke, U., Rolle, S., Daumke, O. and Kettritz, R.
Journal of Biological Chemistry 298
(3): 101598.
March 2022
Genomic variants reducing expression of two endocytic receptors in 46,XY differences of sex development.
Marko, H.L., Hornig, N.C., Betz, R.C., Holterhus, P.M., Altmüller, J., Thiele, H., Fabiano, M., Schweikert, H.U., Braun, D. and Schweizer, U.
Human Mutation 43
(3): 420-433.
March 2022
Effect of sunitinib treatment on skin sodium accumulation in patients with renal cancer: a pilot study.
Markó, L., Dörr, A., Linz, P., van den Meiracker, A.H., Garrelds, I.M., Kuehne, T., Dechend, R., Danser, A.H.J., Flörcken, A. and Müller, D.N.
Hypertension 79
(5): e103-e105.
May 2022
The little skate genome and the evolutionary emergence of wing-like fin appendages.
Marletaz, F., de la Calle-Mustienes, E., Acemel, R.D., Nakamura, T., Paliou, C., Naranjo, S., Martinez-Garcia, P.M., Cases, I., Sleight, V.A., Hirschberger, C., Marcet-Houben, M., Navon, D., Andrescavage, A., Skvortsova, K., Duckett, P.E., Gonzalez-Rajal, A., Bogdanovic, O., Gibcus, J.H., Yang, L., Gallardo-Fuentes, L., Sospedra, I., Lopez-Rios, J., Darbellay, F., Visel, A., Dekker, J., Shubin, N., Gabaldon, T., Tena, J.J., Lupianez, D.G., Rokhsar, D.S. and Gomez-Skarmeta, J.L.
bioRxiv
: 2022.03.21.485123.
22 March 2022
Towards reliable quantification of cell state velocities.
Marot-Lassauzaie, V., Bouman, B.J., Donaghy, F.D., Demerdash, Y., Essers, M.A.G. and Haghverdi, L.
PLoS Computational Biology 18
(9): e1010031.
28 September 2022
Infectious complications of targeted drugs and biotherapies in acute leukemia. Clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL), a joint venture of the European Group for Blood and Marrow Transplantation (EBMT), the European Organization for Research and Treatment of Cancer (EORTC), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN).
Maschmeyer, G., Bullinger, L., Garcia-Vidal, C., Herbrecht, R., Maertens, J., Menna, P., Pagano, L., Thiebaut-Bertrand, A. and Calandra, T.
Leukemia 36
(5): 1215-1226.
May 2022
ATACing single cells with phages.
Maschmeyer, P. and Haas, S.
Molecular Cell 82
(2): 234-236.
20 January 2022
Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases.
Mastracci, T.L., Apte, M., Amundadottir, L.T., Alvarsson, A., Artandi, S., Bellin, M.D., Bernal-Mizrachi, E., Caicedo, A., Campbell-Thompson, M., Cruz-Monserrate, Z., El Ouaamari, A., Gaulton, K.J., Geisz, A., Goodarzi, M.O., Hara, M., Hull-Meichle, R.L., Kleger, A., Klein, A.P., Kopp, J.L., Kulkarni, R.N., Muzumdar, M.D., Naren, A.P., Oakes, S.A., Olesen, S.S., Phelps, E.A., Powers, A.C., Stabler, C.L., Tirkes, T., Whitcomb, D.C., Yadav, D., Yong, J., Zaghloul, N.A., Sander, M. and Pandol, S.J.
Pancreas 51
(9): 1061-1073.
1 October 2022
Molecular and functional characterization of BDNF-overexpressing human retinal pigment epithelial cells established by sleeping beauty transposon-mediated gene transfer.
Mattern, L., Otten, K., Miskey, C., Fuest, M., Izsvák, Z., Ivics, Z., Walter, P., Thumann, G. and Johnen, S.
International Journal of Molecular Sciences 23
(21): 12982.
1 November 2022
The Cl(-)-channel TMEM16A is involved in the generation of cochlear Ca(2+) waves and promotes the refinement of auditory brainstem networks in mice.
Maul, A., Huebner, A.K., Strenzke, N., Moser, T., Rübsamen, R., Jovanovic, S. and Hübner, C.A.
eLife 11
: e72251.
24 February 2022
ClearCNV: CNV calling from NGS panel data in the presence of ambiguity and noise.
May, V., Koch, L., Fischer-Zirnsak, B., Horn, D., Gehle, P., Kornak, U., Beule, D. and Holtgrewe, M.
Bioinformatics 38
(16): 3871-3876.
15 August 2022
Cardio-respiratory motion-corrected 3D cardiac water-fat MRI using model-based image reconstruction.
Mayer, J., Blaszczyk, E., Cipriani, A., Ferrazzi, G., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Magnetic Resonance in Medicine 88
(4): 1561-1574.
October 2022
Assessing the relationship of patient reported outcome measures with functional status in dysferlinopathy: a Rasch analysis approach.
Mayhew, A.G., James, M.K., Moore, U., Sutherland, H., Jacobs, M., Feng, J., Lowes, L.P., Alfano, L.N., Muni Lofra, R., Rufibach, L.E., Rose, K., Duong, T., Bello, L., Pedrosa-Hernández, I., Holsten, S., Sakamoto, C., Canal, A., Sánchez-Aguilera Práxedes, N., Thiele, S., Siener, C., Vandevelde, B., DeWolf, B., Maron, E., Gordish-Dressman, H., Hilsden, H., Guglieri, M., Hogrel, J.Y., Blamire, A.M., Carlier, P.G., Spuler, S., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Pestronk, A., Walter, M.C., Paradas, C., Stojkovic, T., Mori-Yoshimura, M., Bravver, E., Díaz-Manera, J., Pegoraro, E., Mendell, J.R. and Straub, V.
Frontiers in Neurology 13
: 828525.
10 March 2022
Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
McGarvey, A.C., Kopp, W., Vučićević, D., Mattonet, K., Kempfer, R., Hirsekorn, A., Bilić, I., Gil, M., Trinks, A., Merks, A.M., Panáková, D., Pombo, A., Akalin, A., Junker, J.P., Stainier, D.Y.R., Garfield, D., Ohler, U. and Lacadie, S.A.
Cell Genomics 2
(1): 100083.
13 January 2022
Physiological functions of intracellular protein degradation.
McShane, E. and Selbach, M.
Annual Review of Cell and Developmental Biology 38
: 241-262.
October 2022
Paramagnetic rims are a promising diagnostic imaging biomarker in multiple sclerosis.
Meaton, I., Altokhis, A., Allen, C.M., Clarke, M.A., Sinnecker, T., Meier, D., Enzinger, C., Calabrese, M., De Stefano, N., Pitiot, A., Giorgio, A., Schoonheim, M.M., Paul, F., Pawlak, M.A., Schmidt, R., Granziera, C., Kappos, L., Montalban, X., Rovira, À., Wuerfel, Jens and Evangelou, N.
Multiple Sclerosis Journal 28
(14): 2212-2220.
December 2022
Reliable assessment of telomere maintenance mechanisms in neuroblastoma.
Meeser, A., Bartenhagen, C., Werr, L., Hellmann, A.M., Kahlert, Y., Hemstedt, N., Nürnberg, P., Altmüller, J., Ackermann, S., Hero, B., Simon, T., Peifer, M., Fischer, M. and Rosswog, C.
Cell and Bioscience 12
(1): 160.
24 September 2022
Parametric MRI detects aristolochic acid induced acute kidney injury.
Mei, Y., Yang, G., Guo, Y., Zhao, K., Wu, S., Xu, Z., Zhou, S., Yan, C., Seeliger, E., Niendorf, T., Xu, Y. and Feng, Y.
Tomography 8
(6): 2902-2914.
10 December 2022
Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T., Lindemann, P., Welle, A., Trouillet, V., Heißler, S., Nazaré, M. and Selbach, M.
ChemMedChem 17
(19): e202200346.
6 October 2022
Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A., Sprink, T., Noel, J.K., Vázquez-Sarandeses, E., van Hoorn, C., Mohd, S., Loerke, J., Spahn, C.M.T. and Daumke, O.
Nature Communications 13
(1): 7641.
10 December 2022
Analyses of murine lymph node endothelial cell subsets using single-cell RNA sequencing and spectral flow cytometry.
Menzel, L., Zschummel, M. and Rehm, A.
STAR Protocols 3
(2): 101267.
17 June 2022
A high-resolution map of small-scale inversions in the gibbon genome.
Mercuri, L., Palmisano, D., L'Abbate, A., D'Addabbo, P., Montinaro, F., Catacchio, C.R., Hasenfeld, P., Ventura, M., Korbel, J.O., Sanders, A.D., Maggiolini, F.A.M. and Antonacci, F.
Genome Research 32
(10): 1941-1951.
October 2022
The genetic basis of Moyamoya disease.
Mertens, R., Graupera, M., Gerhardt, H., Bersano, A., Tournier-Lasserve, E., Mensah, M.A., Mundlos, S. and Vajkoczy, P.
Translational Stroke Research 13
(1): 25-45.
February 2022
Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models.
Metzger, J.J., Pereda, C., Adhikari, A., Haremaki, T., Galgoczi, S., Siggia, E.D., Brivanlou, A.H. and Etoc, F.
Cell Reports Methods 2
(9): 100297.
19 September 2022
Generation of hiPSC-derived skeletal muscle cells: exploiting the potential of skeletal muscle-derived hiPSCs.
Metzler, E., Escobar, H., Sunaga-Franze, D.Y., Sauer, S., Diecke, S. and Spuler, S.
Biomedicines 10
(5): 1204.
23 May 2022
Diagnostik der Neuromyelitis-optica-Spektrum-Erkrankung (NMOSD) und der MOG-Antikörper-assoziierten Erkrankung (MOGAD) [Diagnosis of neuromyelitis optica spectrum disorder (NMOSD) and MOG Antibody-associated disease (MOGAD)].
Mewes, D., Kuchling, J., Schindler, P., Khalil, A.A.A., Jarius, S., Paul, F. and Chien, C.
Klinische Monatsblatter fur Augenheilkunde 239
(11): 1315-1324.
November 2022
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt, L., Braun, J., Fauchere, F., Vanshylla, K., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Jürchott, K., Mangold, M., Maraj, A., Braginets, A., Böttcher, C., Nitsche, A., de la Rosa, K., Ratswohl, C., Sawitzki, B., Holenya, P., Reimer, U., Sander, L.E., Klein, F., Paul, F., Bellmann-Strobl, J., Thiel, A. and Giesecke-Thiel, C.
Journal of Neurology Neurosurgery and Psychiatry 93
(9): 960-971.
September 2022
Prefrontal-amygdala emotion regulation and depression in multiple sclerosis.
Meyer-Arndt, L., Kuchling, J., Brasanac, J., Hermann, A., Asseyer, S., Bellmann-Strobl, J., Paul, F., Gold, S.M. and Weygandt, M.
Brain Communications 4
(3): fcac152.
13 June 2022
Cutting edge: Serum but not mucosal antibody responses are associated with pre-existing SARS-CoV-2 spike cross-reactive CD4(+) T cells following BNT162b2 vaccination in the elderly.
Meyer-Arndt, L., Schwarz, T., Loyal, L., Henze, L., Kruse, B., Dingeldey, M., Gürcan, K., Uyar-Aydin, Z., Müller, M.A., Drosten, C., Paul, F., Sander, L.E., Demuth, I., Lauster, R., Giesecke-Thiel, C., Braun, J., Corman, V.M. and Thiel, A.
Journal of Immunology 208
(5): 1001-1008.
1 March 2022
Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its host.
Midha, A., Jarquín-Díaz, V.H., Ebner, F., Löber, U., Hayani, R., Kundik, A., Cardilli, A., Heitlinger, E., Forslund, S.K. and Hartmann, S.
Microbiome 10
(1): 229.
16 December 2022
Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C., Lisowski, P., Lickfett, S., Mlody, B., Bünning, M., Genehr, C., Ulrich, C., Wanker, E.E., Diecke, S., Priller, J. and Prigione, A.
Stem Cell Research 65
: 102976.
December 2022
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations.
Miller, T.E., Lareau, C.A., Verga, J.A., DePasquale, E.A.K., Liu, V., Ssozi, D., Sandor, K., Yin, Y., Ludwig, L.S., El Farran, C.A., Morgan, D.M., Satpathy, A.T., Griffin, G.K., Lane, A.A., Love, J.C., Bernstein, B.E., Sankaran, V.G. and van Galen, P.
Nature Biotechnology 40
(7): 1030-1034.
24 February 2022
Suicide nanoplasmids coding for ribosome-inactivating proteins.
Mitdank, H., Tröger, M., Sonntag, A., Shirazi, N.A., Woith, E., Fuchs, H., Kobelt, D., Walther, W. and Weng, A.
European Journal of Pharmaceutical Sciences 170
: 106107.
1 March 2022
Diet quality indices and gastrointestinal cancer risk: results from the Lifelines study.
Moazzen, S., Cortes-Ibañez, F.O., van der Vegt, B., Alizadeh, B.Z. and de Bock, G.H.
European Journal of Nutrition 61
: 317-327.
February 2022
Ferritin trajectories over repeated whole blood donations: results from the FIND+ study.
Moazzen, S., Sweegers, M.G., Janssen, M., Hogema, B.M., Hoekstra, T. and Van den Hurk, K.
Journal of Clinical Medicine 11
(13): 3581.
1 July 2022
Hemodynamic stress-induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein.
Mohamed, B.A., Elkenani, M., Mobarak, S., Marques Rodrigues, D., Annamalai, K., Schnelle, M., Bader, M., Hasenfuss, G. and Toischer, K.
Journal of Cellular and Molecular Medicine 26
(16): 4440-4452.
August 2022
Central macular topographic and volumetric measures: new biomarkers for detection of glaucoma.
Mohammadzadeh, V., Cheng, M., Zadeh, S.H., Edalati, K., Yalzadeh, D., Caprioli, J., Yadav, S., Kadas, E.M., Brandt, A.U. and Nouri-Mahdavi, K.
Translational Vision Science & Technology 11
(7): 25.
July 2022
Targeting angiotensin type 2 receptors located on pressor neurons in the nucleus of the solitary tract to relieve hypertension in mice.
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How shift equivariance impacts metric learning for instance segmentation.
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Cultivation-independent genomes greatly expand taxonomic-profiling capabilities of mOTUs across various environments.
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Proposal for post hoc quality control in instrumented motion analysis using markerless motion capture: development and usability study.
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Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
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Fragmentation, circadian amplitude, and fractal pattern of daily-living physical activity in people with multiple sclerosis: is there relevant information beyond the total amount of physical activity?
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Capillary gel electrophoresis (CGE) for quality control of plasmid DNA in gene therapy: quality control of 20 years stored GMP-grade plasmid DNA.
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The synaptic scaffold protein MPP2 interacts with GABA(A) receptors at the periphery of the postsynaptic density of glutamatergic synapses.
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Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker.
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B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia.
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Prävention des akuten Nierenversagens [Prevention of acute kidney injury].
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Flow cytometry can reliably capture gut microbial composition in healthy adults as well as dysbiosis dynamics in patients with aggressive B-cell non-Hodgkin lymphoma.
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Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.
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October 2022
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Schnoeder, T.M., Schwarzer, A., Jayavelu, A.K., Hsu, C.J., Kirkpatrick, J., Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S.A., Nafria, M., Jiang, L., Dai, Y.T., Chen, Z., Chen, S.J., Kellaway, S.G., Ptasinska, A., Ng, E.S., Stanley, E.G., Elefanty, A.G., Buschbeck, M., Bierhoff, H., Brodt, S., Matziolis, G., Fischer, K.D., Hochhaus, A., Chen, C.W., Heidenreich, O., Mann, M., Lane, S.W., Bullinger, L., Ori, A., von Eyss, B., Bonifer, C. and Heidel, F.
Blood 139
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17 February 2022
Tailoring cardiac synthetic transcriptional modulation towards precision medicine.
Schoger, E., Lelek, S., Panáková, D. and Zelarayán, L.C.
Frontiers in Cardiovascular Medicine 8
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14 January 2022
Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD.
Schroeder-Castagno, M., Del Rio-Serrato, A., Wilhelm, A., Romero-Suárez, S., Schindler, P., Alvarez-González, C., Duchow, A.S., Bellmann-Strobl, J., Ruprecht, K., Hastermann, M., Grütz, G., Wildemann, B., Jarius, S., Schmitz-Hübsch, T., Paul, F. and Infante-Duarte, C.
Journal of Neuroinflammation 19
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1 October 2022
Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours.
Schubert, N.A., Chen, C.Y., Rodríguez, A., Koster, J., Dowless, M., Pfister, S.M., Shields, D.J., Stancato, L.F., Vassal, G., Caron, H.N., van den Boogaard, M.L., Henssen, A.G. and Molenaar, J.J.
European Journal of Cancer 170
: 196-208.
July 2022
Helicobacter pylori - neue Aspekte kommender Leitlinien [Helicobacter pylori - new aspects of forthcoming guidelines].
Schulz, C., Fischbach, W., Sigal, M., Schütte, K., Suerbaum, S. and Malfertheiner, P.
Internist 63
(4): 367-371.
1 March 2022
In prostate cancer cells cytokines are early responders to gravitational changes occurring in parabolic flights.
Schulz, H., Dietrichs, D., Wehland, M., Corydon, T.J., Hemmersbach, R., Liemersdorf, C., Melnik, D., Hübner, N., Saar, K., Infanger, M. and Grimm, D.
International Journal of Molecular Sciences 23
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17 July 2022
Data augmentation via partial nonlinear registration for brain-age prediction.
Schulz, M.A., Koch, A., Guarino, V.E., Kainmueller, D. and Ritter, K.
Lecture Notes in Computer Science 13596
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2022
SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolution.
Schumann, V.F., de Castro Cuadrat, R.R., Wyler, E., Wurmus, R., Deter, A., Quedenau, C., Dohmen, J., Faxel, M., Borodina, T., Blume, A., Freimuth, J., Meixner, M., Grau, J.H., Liere, K., Hackenbeck, T., Zietzschmann, F., Gnirss, R., Böckelmann, U., Uyar, B., Franke, V., Barke, N., Altmüller, J., Rajewsky, N., Landthaler, M. and Akalin, A.
Science of the Total Environment 853
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20 December 2022
Whole-body magnetic resonance imaging in the large population-based German National Cohort study: predictive capability of automated image quality assessment for protocol repetitions.
Schuppert, C., von Krüchten, R., Hirsch, J.G., Rospleszcz, S., Hoinkiss, D.C., Selder, S., Köhn, A., von Stackelberg, O., Peters, A., Völzke, H., Kröncke, T., Niendorf, T., Forsting, M., Hosten, N., Hendel, T., Pischon, T., Jöckel, K.H., Kaaks, R., Bamberg, F., Kauczor, H.U., Günther, M. and Schlett, C.L.
Investigative Radiology 57
(7): 478-487.
1 July 2022
Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine.
Schwab, K., Chasapopoulou, Z., Frahm, S., Magbagbeolu, M., Cranston, A., Harrington, C.R., Wischik, C.M., Theuring, F. and Riedel, G.
Cellular Signalling 97
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September 2022
On the relation between input and output distributions of scRNA-seq experiments.
Schwabe, D. and Falcke, M.
Bioinformatics 38
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1 March 2022
Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline: a randomized clinical tTrial.
Schwarz, C., Benson, G.S., Horn, N., Wurdack, K., Grittner, U., Schilling, R., Märschenz, S., Köbe, T., Hofer, S.J., Magnes, C., Stekovic, S., Eisenberg, T., Sigrist, S.J., Schmitz, D., Wirth, M., Madeo, F. and Flöel, A.
JAMA Network Open 5
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26 May 2022
Eating patterns during pregnancy and postpartum and their association with diet quality and energy intake.
Schwedhelm, C., Lipsky, L.M., Temmen, C.D. and Nansel, T.R.
Nutrients 14
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10 March 2022
Evidence of neural crest cell origin of a DICER1 mutant CNS sarcoma in a child with DICER1 syndrome and NRAS-mutant neurocutaneous melanosis.
Schweizer, L., Hartmann, W., Koch, A., Nunninger, M., Thomale, U.W., Pennacchietti, V., Tietze, A., Horn, D., Pajtler, K.W., Hirsch, S., Wieland, I., Deubzer, H., Rossi, R., Hernáiz Driever, P., von Hoff, K. and von Zezschwitz, B.
Neuropathology and Applied Neurobiology 48
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October 2022
3D-printed tissue-simulating phantoms for near-infrared fluorescence imaging of rheumatoid diseases.
Schädel-Ebner, S., Hirsch, O., Gladytz, T., Gutkelch, D., Licha, K., Berger, J. and Grosenick, D.
Journal of Biomedical Optics 27
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July 2022
Highly conserved interaction profiles between clinically relevant mutants of the cytomegalovirus CDK-like kinase pUL97 and human cyclins: functional significance of cyclin H.
Schütz, M., Müller, R., Socher, E., Wangen, C., Full, F., Wyler, E., Wong, D., Scherer, M., Stamminger, T., Chou, S., Rawlinson, W.D., Hamilton, S.T., Sticht, H. and Marschall, M.
International Journal of Molecular Sciences 23
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5 October 2022
Evaluation of lake sedimentary ancient DNA metabarcoding to assess fungal biodiversity in Arctic paleoecosystems.
Seeber, P.A., Hippel, B., Kauserud, H., Löber, U., Stoof‐Leichsenring, K.R., Herzschuh, U. and Epp, L.S.
Environmental DNA 4
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September 2022
Pathogenic variants in cardiomyopathy disorder genes underlie pediatric myocarditis - Further impact of heterozygous immune disorder gene variants?
Seidel, F., Laser, K.T., Klingel, K., Dartsch, J., Theisen, S., Pickardt, T., Holtgrewe, M., Gärtner, A., Berger, F., Beule, D., Milting, H., Schubert, S., Klaassen, S. and Kühnisch, J.
Journal of Cardiovascular Development and Disease 9
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5 July 2022
Clinical characteristics and outcome of biopsy-proven myocarditis in children - Results of the German prospective multicentre registry "MYKKE".
Seidel, F., Opgen-Rhein, B., Rentzsch, A., Boehne, M., Wannenmacher, B., Boecker, D., Reineker, K., Grafmann, M., Wiegand, G., Hecht, T., Kiski, D., Fischer, M., Papakostas, K., Ruf, B., Kramp, J., Khalil, M., Kaestner, M., Steinmetz, M., Fischer, G., Özcan, S., Freudenthal, N., Schweigmann, U., Hellwig, R., Pickardt, T., Klingel, K., Messroghli, D. and Schubert, S.
International Journal of Cardiology 357
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15 June 2022
Compensatory upregulation of anti-beta-adrenergic receptor antibody levels might prevent heart failure presentation in pediatric myocarditis.
Seidel, F., Scheibenbogen, C., Heidecke, H., Opgen-Rhein, B., Pickardt, T., Klingel, K., Berger, F., Messroghli, D. and Schubert, S.
Frontiers in Pediatrics 10
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28 April 2022
Optocoder: computational decoding of spatially indexed bead arrays.
Senel, E., Rajewsky, N. and Karaiskos, N.
NAR Genomics and Bioinformatics 4
(2): lqac042.
June 2022
A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants.
Shahan, R., Hsu, C.W., Nolan, T.M., Cole, B.J., Taylor, I.W., Greenstreet, L., Zhang, S., Afanassiev, A., Vlot, A.H.C., Schiebinger, G., Benfey, P.N. and Ohler, U.
Developmental Cell 57
(4): 543-560.
28 February 2022
K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.
Shearer, R.F., Typas, D., Coscia, F., Schovsbo, S., Kruse, T., Mund, A. and Mailand, N.
EMBO Journal 41
(9): e110145.
2 May 2022
SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition.
Shih, A.Z.L., Chen, Y.C., Speckmann, T., Søndergaard, E., Schürmann, A., Verchere, C.B. and Willnow, T.E.
Molecular Metabolism 65
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November 2022
Amelioration of endotoxemia by a synthetic analog of Omega-3 epoxyeicosanoids.
Shikuma, A., Kami, D., Maeda, R., Suzuki, Y., Sano, A., Taya, T., Ogata, T., Konkel, A., Matoba, S., Schunck, W.H. and Gojo, S.
Frontiers in Immunology 13
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24 February 2022
Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.
Shum, M., Segawa, M., Gharakhanian, R., Viñuela, A., Wortham, M., Baghdasarian, S., Wolf, D.M., Sereda, S.B., Nocito, L., Stiles, L., Zhou, Z., Gutierrez, V., Sander, M., Shirihai, O.S. and Liesa, M.
Molecular Metabolism 55
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January 2022
Graph neural networks for learning molecular excitation spectra.
Singh, K., Münchmeyer, J., Weber, L., Leser, U. and Bande, A.
Journal of Chemical Theory and Computation 18
(7): 4408-4417.
12 July 2022
A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish.
Singh, S.P., Chawla, P., Hnatiuk, A., Kamel, M., Silva, L.D., Spanjaard, B., Eski, S.E., Janjuha, S., Olivares-Chauvet, P., Kayisoglu, O., Rost, F., Bläsche, J., Kränkel, A., Petzold, A., Kurth, T., Reinhardt, S., Junker, J.P. and Ninov, N.
Development 149
(2): dev199853.
January 2022
Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy.
Sinha Ray, S., Dutta, D., Dennys, C., Powers, S., Roussel, F., Lisowski, P., Glažar, P., Zhang, X., Biswas, P., Caporale, J.R., Rajewsky, N., Bickle, M., Wein, N., Bellen, H.J., Likhite, S., Marcogliese, P.C. and Meyer, K.C.
Cell Reports 41
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6 December 2022
CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment.
Skroblyn, T., Joedicke, J.J., Pfau, M., Krüger, K., Bourquin, J.P., Izraeli, S., Eckert, C. and Höpken, U.E.
Journal of Pathology 258
(1): 12-25.
September 2022
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Smajić, S., Prada-Medina, C.A., Landoulsi, Z., Ghelfi, J., Delcambre, S., Dietrich, C., Jarazo, J., Henck, J., Balachandran, S., Pachchek, S., Morris, C.M., Antony, P., Timmermann, B., Sauer, S., Pereira, S.L., Schwamborn, J.C., May, P., Grünewald, A. and Spielmann, M.
Brain 145
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March 2022
Dysregulated autoantibodies targeting vaso- and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity.
Sotzny, F., Filgueiras, I.S., Kedor, C., Freitag, H., Wittke, K., Bauer, S., Sepúlveda, N., Mathias da Fonseca, D.L., Baiocchi, G.C., Marques, A.H.C., Kim, M., Lange, T., Plaça, D.R., Luebber, F., Paulus, F.M., De Vito, R., Jurisica, I., Schulze-Forster, K., Paul, F., Bellmann-Strobl, J., Rust, R., Hoppmann, U., Shoenfeld, Y., Riemekasten, G., Heidecke, H., Cabral-Marques, O. and Scheibenbogen, C.
Frontiers in Immunology 13
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27 September 2022
Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
Specker, E., Matthes, S., Wesolowski, R., Schütz, A., Grohmann, M., Alenina, N., Pleimes, D., Mallow, K., Neuenschwander, M., Gogolin, A., Weise, M., Pfeifer, J., Ziebart, N., Heinemann, U., von Kries, J.P., Nazaré, M. and Bader, M.
Journal of Medicinal Chemistry 65
(16): 11126-11149.
25 August 2022
Berlin Registry of Neuroimmunological entities (BERLimmun): protocol of a prospective observational study.
Sperber, P.S., Brandt, A.U., Zimmermann, H.G., Bahr, L.S., Chien, C., Rekers, S., Mähler, A., Böttcher, C., Asseyer, S., Duchow, A.S., Bellmann-Strobl, J., Ruprecht, K., Paul, F. and Schmitz-Hübsch, T.
BMC Neurology 22
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14 December 2022
Why angiotensin II is a poor choice for circulatory support of ventilated COVID-19 patients compared to vasopressin.
Speth, R.C. and Bader, M.
Medical Research Archives 10
(9): 3079.
September 2022
mRNA-mediated delivery of gene editing tools to human primary muscle stem cells.
Stadelmann, C., Di Francescantonio, S., Marg, A., Müthel, S., Spuler, S. and Escobar, H.
Molecular Therapy - Nucleic Acids 28
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14 June 2022
Nationwide registry-based analysis of infective endocarditis risk after pulmonary valve replacement.
Stammnitz, Clara, Huscher, Dörte, Bauer, Ulrike M M, Urban, Aleksandra, Nordmeyer, Johannes, Schubert, Stephan, Photiadis, Joachim, Berger, Felix and Klaassen, S.
Journal of the American Heart Association 11
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18 February 2022
Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas.
Staudacher, J.J., Arnold, A., Kühl, A.A., Pötzsch, M., Daum, S., Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. and Treese, C.
BMC Cancer 22
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5 September 2022
DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M., Denker, S. and Schmitt, C.A.
Cancers 14
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11 March 2022
Obesity is associated with myelin oligodendrocyte glycoprotein antibody-associated disease in acute optic neuritis.
Stiebel-Kalish, H., Rubarth, K., Shouchane-Blum, K., Tiosano, A., Lotan, I., Hellmann, M.A., Wilf-Yarkoni, A., Bialer, O., Flanagan, E.P., Pittock, S.J., Bhatti, M.T., Schmitz-Hübsch, T., Paul, F., Asseyer, S. and Chen, J.J.
Scientific Reports 12
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9 December 2022
Editorial: Mitochondria as a hub in cellular signaling.
Stoolman, J.S., Porcelli, A.M. and Martínez-Reyes, I.
Frontiers in Cell and Developmental Biology 10
: 981464.
15 August 2022
Lifetime and current depression in the German National Cohort (NAKO).
Streit, F., Zillich, L., Frank, J., Kleineidam, L., Wagner, M., Baune, B.T., Klinger-König, J., Grabe, H.J., Pabst, A., Riedel-Heller, S.G., Schmiedek, F., Schmidt, B., Erhardt, A., Deckert, J., Rietschel, M. and Berger, K.
World Journal of Biological Psychiatry 24
(10): 865-880.
17 February 2022
Comorbidities rather than older age define outcome in adult patients with tumors of the Ewing sarcoma family.
Striefler, J.K., Schmiester, M., Brandes, F., Dörr, A., Pahl, S., Kaul, D., Rau, D., Dobrindt, E.M., Koulaxouzidis, G., Bullinger, L., Märdian, S. and Flörcken, A.
Cancer Medicine 11
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September 2022
MCT1 is a predictive marker for lenalidomide maintenance therapy in multiple myeloma.
Stroh, J., Seckinger, A., Heider, M., Rudelius, M., Eichner, R., Schick, M., Slawska, J., Emde, M., Salwender, H., Bertsch, U., Goldschmidt, H., Weisel, K.C., Scheid, C., Keller, U., Hose, D. and Bassermann, F.
Blood Advances 6
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25 January 2022
Cell type diversity in a developing octopus brain.
Styfhals, R., Zolotarov, G., Hulselmans, G., Spanier, K.I., Poovathingal, S., Elagoz, A.M., De Winter, S., Deryckere, A., Rajewsky, N., Ponte, G., Fiorito, G., Aerts, S. and Seuntjens, E.
Nature Communications 13
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30 November 2022
Pan-claudin family interactome analysis reveals shared and specific interactions.
Suarez Artiles, L., Breiderhoff, T., Girardello, R., Gonschior, H., Rodius, S., Lesur, A., Reimer, U., Ramberger, E., Perez-Hernandez, D., Müller, D., Mertins, P. and Dittmar, G.
Cell Reports 41
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8 November 2022
Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo.
Subramanian, S., Busch, C.J.L., Molawi, K., Geirsdottir, L., Maurizio, J., Vargas Aguilar, S., Belahbib, H., Gimenez, G., Yuda, R.A.A., Burkon, M., Favret, J., Gholamhosseinian Najjar, S., de Laval, B., Kandalla, P.K., Sarrazin, S., Alexopoulou, L. and Sieweke, M.H.
Nature Immunology 23
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March 2022
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer.
Sugimoto, Y. and Ratcliffe, P.J.
Nature Structural & Molecular Biology 29
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September 2022
Male carriers of HLA-C*04:01 have increased risk of cardiac injury in COVID-19.
Suwalski, P., Violano, M., Müller, M., Patriki, D., Thibeault, C., Quedenau, C., Wang, X., Karadeniz, Z., Saccomanno, J., Doehn, J.M., Hübner, R.H., Hinzmann, B., Beer, H.J., Wiggli, B., Siemann, S., Suttorp, N., Witzenrath, M., Hippenstiel, S., Skurk, C., Poller, W., Sander, L.E., Kurth, F., Borodina, T., Guettouche, T., Landmesser, U. and Heidecker, B.
Journal of Cardiovascular Aging 2
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27 June 2022
Aldosteronantagonisten "revisited" [Aldosterone antagonists revisited].
Swolinsky, J. and Schmidt-Ott, K.
Nephrologe 17
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July 2022
Discordance between estimated and measured changes in plasma volume among patients with acute heart failure.
Swolinsky, J.S., Tuvshinbat, E., Leistner, D.M., Edelmann, F., Knebel, F., Nerger, N.P., Lemke, C., Roehle, R., Haase, M., Costanzo, M.R., Rauch, G., Mitrovic, V., Gasanin, E., Meier, D., McCullough, P.A., Eckardt, K.U., Molitoris, B.A. and Schmidt-Ott, K.M.
ESC Heart Failure 9
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February 2022
Skeletal muscle derived Musclin protects the heart during pathological overload.
Szaroszyk, M., Kattih, B., Martin-Garrido, A., Trogisch, F.A., Dittrich, G.M., Grund, A., Abouissa, A., Derlin, K., Meier, M., Holler, T., Korf-Klingebiel, M., Völker, K., Macedo, T.G., Tortola, C.P., Boschmann, M., Huang, N., Froese, N., Zwadlo, C., Malek Mohammadi, M., Luo, X., Wagner, M., Cordero, J., Geffers, R., Batkai, S., Thum, T., Bork, N., Nikolaev, V.O., Müller, O.J., Katus, H.A., El-Armouche, A., Kraft, T., Springer, J., Dobreva, G., Wollert, K.C., Fielitz, J., von Haehling, S., Kuhn, M., Bauersachs, J. and Heineke, J.
Nature Communications 13
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10 January 2022
Spacemake: processing and analysis of large-scale spatial transcriptomics data.
Sztanka-Toth, T.R., Jens, M., Karaiskos, N. and Rajewsky, N.
GigaScience 11
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19 July 2022
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The landscape of genetic aberrations in myxofibrosarcoma.
Takeuchi, Y., Yoshida, K., Halik, A., Kunitz, A., Suzuki, H., Kakiuchi, N., Shiozawa, Y., Yokoyama, A., Inoue, Y., Hirano, T., Yoshizato, T., Aoki, K., Fujii, Y., Nannya, Y., Makishima, H., Pfitzner, B.M., Bullinger, L., Hirata, M., Jinnouchi, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Okamoto, T., Haga, H., Ogawa, S. and Damm, F.
International Journal of Cancer 151
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15 August 2022
Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease.
Talmor-Barkan, Y., Bar, N., Shaul, A.A., Shahaf, N., Godneva, A., Bussi, Y., Lotan-Pompan, M., Weinberger, A., Shechter, A., Chezar-Azerrad, C., Arow, Z., Hammer, Y., Chechi, K., Forslund, S.K., Fromentin, S., Dumas, M.E., Ehrlich, S.D., Pedersen, O., Kornowski, R. and Segal, E.
Nature Medicine 28
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February 2022
Concomitant cytotoxic effector differentiation of CD4(+) and CD8(+) T cells in response to EBV-Infected B cells.
Tamura, Y., Yamane, K., Kawano, Y., Bullinger, L., Wirtz, T., Weber, T., Sander, S., Ohki, S., Kitajima, Y., Okada, S., Rajewsky, K. and Yasuda, T.
Cancers 14
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25 August 2022
Birth order, caesarean section, or daycare attendance in relation to child- and adult-onset type 1 diabetes: results from the german national cohort.
Tanoey, J., Baechle, C., Brenner, H., Deckert, A., Fricke, J., Günther, K., Karch, A., Keil, T., Kluttig, A., Leitzmann, M., Mikolajczyk, R., Obi, N., Pischon, T., Schikowski, T., Schipf, S.M., Schulze, M.B., Sedlmeier, A., Moreno Velásquez, I., Weber, K.S., Völzke, H., Ahrens, W., Gastell, S., Holleczek, B., Jöckel, K.H., Katzke, V., Lieb, W., Michels, K.B., Schmidt, B., Teismann, H. and Becher, H.
International Journal of Environmental Research and Public Health 19
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31 August 2022
Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi, Y., Arango-Ossa, J.E., Zhou, Y., Bernard, E., Thomas, I., Gilkes, A., Freeman, S., Pradat, Y., Johnson, S.J., Hills, R., Dillon, R., Levine, M.F., Leongamornlert, D., Butler, A., Ganser, A., Bullinger, L., Döhner, K., Ottmann, O., Adams, R., Döhner, H., Campbell, P.J., Burnett, A.K., Dennis, M., Russell, N.H., Devlin, S.M., Huntly, B.J.P. and Papaemmanuil, E.
Nature Communications 13
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8 August 2022
Pharmacological inhibition of adipose tissue Adipose Triglyceride Lipase (ATGL) by Atglistatin prevents catecholamine-induced myocardial damage.
Thiele, A., Luettges, K., Ritter, D., Beyhoff, N., Smeir, E., Grune, J., Steinhoff, J.S., Schupp, M., Klopfleisch, R., Rothe, M., Wilck, N., Bartolomaeus, H., Migglautsch, A.K., Breinbauer, R., Kershaw, E.E., Grabner, G.F., Zechner, R., Kintscher, U. and Foryst-Ludwig, A.
Cardiovascular Research 118
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July 2022
Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.
Thomalla, D., Beckmann, L., Grimm, C., Oliverio, M., Meder, L., Herling, C.D., Nieper, P., Feldmann, T., Merkel, O., Lorsy, E., da Palma Guerreiro, A., von Jan, J., Kisis, I., Wasserburger, E., Claasen, J., Faitschuk-Meyer, E., Altmüller, J., Nürnberg, P., Yang, T.P., Lienhard, M., Herwig, R., Kreuzer, K.A., Pallasch, C.P., Buettner, R., Schäfer, S.C., Hartley, J., Abken, H., Peifer, M., Kashkar, H., Knittel, G., Eichhorst, B., Ullrich, R.T., Herling, M., Reinhardt, H.C., Hallek, M., Schweiger, M.R. and Frenzel, L.P.
Blood 140
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17 November 2022
Genomic evolution and personalized therapy of an infantile fibrosarcoma harboring an NTRK oncogenic fusion.
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28 March 2022
Analysis of single-cell transcriptome data in drosophila.
Yousefian, S., Musillo, M.J. and Bageritz, J.
Methods in Molecular Biology 2540
(3): 93-111.
19 August 2022
Recapitulating early human development with 8C-like cells.
Yu, X., Liang, S., Chen, M., Yu, H., Li, R., Qu, Y., Kong, X., Guo, R., Zheng, R., Izsvak, Z., Sun, C., Yang, M. and Wang, J.
Cell Reports 39
(12): 110994.
21 June 2022
Z
Tph2 gene expression defines ethanol drinking behavior in mice.
Zaniewska, M., Mosienko, V., Bader, M. and Alenina, N.
Cells 11
(5): 874.
3 March 2022
2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death.
Zeppenfeld, K., Tfelt-Hansen, J., de Riva, M., Winkel, B.G., Behr, E.R., Blom, N.A., Charron, P., Corrado, D., Dagres, N., de Chillou, C., Eckardt, L., Friede, T., Haugaa, K.H., Hocini, M., Lambiase, P.D., Marijon, E., Merino, J.L., Peichl, P., Priori, S.G., Reichlin, T., Schulz-Menger, J., Sticherling, C., Tzeis, S., Verstrael, A. and Volterrani, M.
European Heart Journal 43
(40): 3997-4126.
21 October 2022
Proton-gated anion transport governs macropinosome shrinkage.
Zeziulia, M., Blin, S., Schmitt, F.W., Lehmann, M. and Jentsch, T.J.
Nature Cell Biology 24
(6): 885-895.
June 2022
Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.
Zhai, Y., Singh, P., Dolnik, A., Brazda, P., Atlasy, N., Del Gaudio, N., Döhner, K., Döhner, H., Minucci, S., Martens, J., Altucci, L., Megchelenbrink, W., Bullinger, L. and Stunnenberg, H.G.
Molecular Cancer 21
(1): 166.
19 August 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Zhang, S., Cao, S., Gong, M., Zhang, W., Zhang, W., Zhu, Z., Wu, S., Yue, Y., Qian, W., Ma, Q., Wang, S. and Wang, Z.
Cancer Biology & Therapy 23
(1): 336-347.
22 April 2022
RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis.
Zhang, Y., Wang, C., Sun, M., Jin, Y., Braz, C.U., Khatib, H., Hacker, T.A., Liss, M., Gotthardt, M., Granzier, H., Ge, Y. and Guo, W.
FASEB Journal 36
(5): e22302.
May 2022
Role of TRPC6 in kidney damage after acute ischemic kidney injury.
Zheng, Z., Tsvetkov, D., Bartolomaeus, T.U.P., Erdogan, C., Krügel, U., Schleifenbaum, J., Schaefer, M., Nürnberg, B., Chai, X., Ludwig, F.A., N'diaye, G., Köhler, M.B., Wu, K., Gollasch, M. and Markó, L.
Scientific Reports 12
(1): 3038.
22 February 2022
In vivo inhibition of TRPC6 by SH045 attenuates renal fibrosis in a New Zealand Obese (NZO) mouse model of metabolic syndrome.
Zheng, Z., Xu, Y., Krügel, U., Schaefer, M., Grune, T., Nürnberg, B., Köhler, M.B., Gollasch, M., Tsvetkov, D. and Marko, L.
International Journal of Molecular Sciences 23
(12): 6870.
20 June 2022
A preclinical study on brugada syndrome with a CACNB2 variant using human cardiomyocytes from induced pluripotent stem cells.
Zhong, R., Schimanski, T., Zhang, F., Lan, H., Hohn, A., Xu, Q., Huang, M., Liao, Z., Qiao, L., Yang, Z., Li, Y., Zhao, Z., Li, X., Rose, L., Albers, S., Maywald, L., Müller, J., Dinkel, H., Saguner, A., Janssen, J.W.G., Telugu, N.S., Xi, Y., Lang, S., Kleinsorge, M., Duru, F., Zhou, X., Diecke, S., Cyganek, L., Akin, I. and El-Battrawy, I.
International Journal of Molecular Sciences 23
(15): 8313.
1 August 2022
Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.
Zhou, D., Borsa, M., Puleston, D.J., Zellner, S., Capera, J., Sanderson, S., Schifferer, M., Hester, S.S., Ge, X., Fischer, R., Jostins, L., Behrends, C., Alsaleh, G. and Simon, A.K.
Nature Communications 13
(1): 5174.
2 September 2022
Novel targets, treatments, and advanced models for intracerebral haemorrhage.
Zille, M., Farr, T.D., Keep, R.F., Römer, C., Xi, G. and Boltze, J.
EBioMedicine 76
: 103880.
12 February 2022
Autophagy takes it all - autophagy inducers target immune aging.
Zinecker, H. and Simon, A.K.
Disease Models & Mechanisms 15
(1): dmm049345.
31 January 2022
HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U., Milek, M., Minia, I., Vieira-Vieira, C.H., Müller, S., Mastrobuoni, G., Hazapis, O.G., Del Giudice, S., Schwefel, D., Bley, N., Voigt, F., Chao, J.A., Kempa, S., Hüttelmaier, S., Selbach, M. and Landthaler, M.
Nature Communications 13
(1): 2727.
18 May 2022
MicroRNAs are deeply linked to the emergence of the complex octopus brain.
Zolotarov, G., Fromm, B., Legnini, I., Ayoub, S., Polese, G., Maselli, V., Chabot, P.J., Vinther, J., Styfhals, R., Seuntjens, E., Di Cosmo, A., Peterson, K.J. and Rajewsky, N.
Science Advances 8
(47): eadd9938.
25 November 2022
The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G., Vanzo, R., Amitash, S., Martín-Doncel, E., Coscia, F., Mund, A., Lerdrup, M., Benada, J., Boos, D. and Toledo, L.
Molecular Cell 82
(18): 3350-3365.
15 September 2022
Disease relevance of rare VPS13B missense variants for neurodevelopmental Cohen syndrome.
Zorn, M., Kühnisch, J., Bachmann, S. and Seifert, W.
Scientific Reports 12
(1): 9686.
11 June 2022
Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling law.
Zou, X., Schaefke, B., Li, Y., Jia, F., Sun, W., Li, G., Liang, W., Reif, T., Heyd, F., Gao, Q., Tian, S., Li, Y., Tang, Y., Fang, L., Hu, Y. and Chen, W.
Life Science Alliance 5
(4): e202101333.
April 2022
Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros.
Zywitza, V., Frahm, S., Krüger, N., Weise, A., Göritz, F., Hermes, R., Holtze, S., Colleoni, S., Galli, C., Drukker, M., Hildebrandt, T.B. and Diecke, S.
iScience 25
(11): 105414.
18 November 2022
Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction.
Zywitza, V., Rusha, E., Shaposhnikov, D., Ruiz-Orera, J., Telugu, N., Rishko, V., Hayashi, M., Michel, G., Wittler, L., Stejskal, J., Holtze, S., Göritz, F., Hermes, R., Wang, J., Izsvák, Z., Colleoni, S., Lazzari, G., Galli, C., Hildebrandt, T.B., Hayashi, K., Diecke, S. and Drukker, M.
Scientific Reports 12
(1): 3100.
8 March 2022
Ö
Soluble urokinase plasminogen activator receptor levels are associated with severity of fibrosis in patients with primary sclerosing cholangitis.
Özdirik, B., Maibier, M., Scherf, M., Nicklaus, J.M., Frohme, J., Puengel, T., Meyer Zum Büschenfelde, D., Tacke, F., Mueller, T. and Sigal, M.
Journal of Clinical Medicine 11
(9): 2479.
28 April 2022
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