Article
Pan-cancer analysis of whole genomes.
Nature 578
(7793): 82-93.
6 February 2020
Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis.
Abrahamyan, S., Eberspächer, B., Hoshi, M.M., Aly, L., Luessi, F., Groppa, S., Klotz, L., Meuth, S.G., Schroeder, C., Grüter, T., Tackenberg, B., Paul, F., Then-Bergh, F., Kümpfel, T., Weber, F., Stangel, M., Bayas, A., Wildemann, B., Heesen, C., Zettl, U., Warnke, C., Antony, G., Hessler, N., Wiendl, H., Bittner, S., Hemmer, B., Gold, R., Salmen, A. and Ruprecht, K.
Journal of Neurology Neurosurgery and Psychiatry 91
(7): 681-686.
July 2020
SUMOylation of enzymes and ion channels in sensory neurons protects against metabolic dysfunction, neuropathy, and sensory loss in diabetes.
Agarwal, N., Taberner, F.J., Rangel Rojas, D., Moroni, M., Omberbasic, D., Njoo, C., Andrieux, A., Gupta, P., Bali, K.K., Herpel, E., Faghihi, F., Fleming, T., Dejean, A., Lechner, S.G., Nawroth, P.P., Lewin, G.R. and Kuner, R.
Neuron 107
(6): 1141-1159.
23 September 2020
Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica.
Agasing, A.M., Wu, Q., Khatri, B., Borisow, N., Ruprecht, K., Brandt, A.U., Gawde, S., Kumar, G., Quinn, J.L., Ko, R.M., Mao-Draayer, Y., Lessard, C.J., Paul, F. and Axtell, R.C.
Nature Communications 11
(1): 2856.
5 June 2020
Consumption of fish and long-chain n-3 polyunsaturated fatty acids is associated with reduced risk of colorectal cancer in a large European cohort.
Aglago, E.K., Huybrechts, I., Murphy, N., Casagrande, C., Nicolas, G., Pischon, T., Fedirko, V., Severi, G., Boutron-Ruault, M.C., Fournier, A., Katzke, V., Kühn, T., Olsen, A., Tjønneland, A., Dahm, C.C., Overvad, K., Lasheras, C., Agudo, A., Sánchez, M.J., Amiano, P., Huerta, J.M., Ardanaz, E., Perez-Cornago, A., Trichopoulou, A., Karakatsani, A., Martimianaki, G., Palli, D., Pala, V., Tumino, R., Naccarati, A., Panico, S., Bueno-de-Mesquita, B., May, A., Derksen, J.W.G., Hellstrand, S., Ohlsson, B., Wennberg, M., Van Guelpen, B., Skeie, G., Brustad, M., Weiderpass, E., Cross, A.J., Ward, H., Riboli, E., Norat, T., Chajes, V. and Gunter, M.J.
Clinical Gastroenterology and Hepatology 18
(3): 654-666.
March 2020
CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development.
Aherrahrou, R., Kulle, A.E., Alenina, N., Werner, R., Vens-Cappell, S., Bader, M., Schunkert, H., Erdmann, J. and Aherrahrou, Z.
Scientific Reports 10
(1): 8792.
29 May 2020
Erforschung von Erkrankungen in der NAKO Gesundheitsstudie: die wichtigsten gesundheitlichen Endpunkte und ihre Erfassung [The investigation of health outcomes in the German National Cohort: the most relevant endpoints and their assessment].
Ahrens, W., Greiser, K.H., Linseisen, J., Pischon, T. and Pigeot, I.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(4): 376-384.
April 2020
Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model.
Akpa, C.A., Kleo, K., Oker, E., Tomaszewski, N., Messerschmidt, C., López, C., Wagener, R., Oehl-Huber, K., Dettmer, K., Schoeler, A., Lenze, D., Oefner, P.J., Beule, D., Siebert, R., Capper, D., Dimitrova, L. and Hummel, M.
BMC Cancer 20
(1): 427.
14 May 2020
Fingolimod after a first unilateral episode of acute optic neuritis (MOVING) - preliminary results from a randomized, rater-blind, active-controlled, phase 2 trial.
Albert, C., Mikolajczak, J., Liekfeld, A., Piper, S.K., Scheel, M., Zimmermann, H.G., Nowak, C., Dörr, J., Bellmann-Strobl, J., Chien, C., Brandt, A.U., Paul, F. and Hoffmann, O.
BMC Neurology 20
(1): 75.
3 March 2020
Pursuing experimental reproducibility: an efficient protocol for the preparation of cerebrospinal fluid samples for NMR-based metabolomics and analysis of sample degradation.
Albrecht, B., Voronina, E., Schipke, C., Peters, O., Parr, M.K., Díaz-Hernández, M.D. and Schlörer, N.E.
Metabolites 10
(6): 251.
16 June 2020
Tumor-derived extracellular vesicles impair CD171-specific CD4(+) CAR T cell efficacy.
Ali, S., Toews, K., Schwiebert, S., Klaus, A., Winkler, A., Grunewald, L., Oevermann, L., Deubzer, H.E., Tüns, A., Jensen, M.C., Henssen, A.G., Eggert, A., Schulte, J.H., Schwich, E., Rebmann, V., Schramm, A. and Künkele, A.
Frontiers in Immunology 11
: 531.
31 March 2020
Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L., Peeva, P., Ramos-Prats, A., Alenina, N., Winter, Y. and Rivalan, M.
Behavioural Brain Research 377
: 112188.
13 January 2020
DNA sonication inverse PCR for genome scale analysis of uncharacterized flanking sequences.
Alquezar‐Planas, D.E., Löber, U., Cui, P., Quedenau, C., Chen, W. and Greenwood, A.D.
Methods in Ecology and Evolution
22 September 2020
Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses.
Alsaleh, G., Panse, I., Swadling, L., Zhang, H., Richter, F.C., Meyer, A., Lord, J., Barnes, E., Klenerman, P., Green, C. and Simon, A.K.
eLife 9
: e57950.
15 December 2020
A palladium-catalyzed domino reaction to access 3-amino-2H-indazoles from hydrazines and 2-halobenzonitriles.
Alsalim, R., Lindemann, P., López-Alberca, M.P., Miksche, S., Czechtizky, W., Halland, N. and Nazaré, M.
Organic Letters 22
(18): 7393-7396.
18 September 2020
RNA sequencing of human peripheral blood cells indicates upregulation of immune-related genes in Huntington's disease.
Andrade-Navarro, M.A., Mühlenberg, K., Spruth, E.J., Mah, N., González-López, A., Andreani, T., Russ, J., Huska, M.R., Muro, E.M., Fontaine, J.F., Amstislavskiy, V., Soldatov, A., Nietfeld, W., Wanker, E.E. and Priller, J.
Frontiers in Neurology 11
: 573560.
27 November 2020
Imaging of clinically unrecognized myocardial fibrosis in patients with suspected coronary artery disease.
Antiochos, P., Ge, Y., Steel, K., Bingham, S., Abdullah, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
Journal of the American College of Cardiology 76
(8): 945-957.
25 August 2020
Evaluation of stress cardiac magnetic resonance imaging in risk reclassification of patients with suspected coronary artery disease.
Antiochos, P., Ge, Y., Steel, K., Chen, Y.Y., Bingham, S., Abdullah, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P., Murthy, V.L. and Kwong, R.Y.
JAMA Cardiology 5
(12): 1401-1409.
December 2020
Early life stress regulates cardiac development through an IL4-glucocorticoid signaling balance.
Apaydin, D.C., Jaramillo, P.A.M., Corradi, L., Cosco, F., Rathjen, F.G., Kammertoens, T., Filosa, A. and Sawamiphak, S.
Cell Reports 33
(7): 108404.
17 November 2020
Gadobutrol-enhanced cardiac magnetic resonance imaging for detection of coronary artery disease.
Arai, A.E., Schulz-Menger, J., Berman, D., Mahrholdt, H., Han, Y., Bandettini, W.P., Gutberlet, M., Abraham, A., Woodard, P.K., Selvanayagam, J.B., McCann, G.P., Hamilton-Craig, C., Schoepf, U.J., Tan, R.S., Kramer, C.M., Friedrich, M.G., Haverstock, D., Liu, Z., Brueggenwerth, G., Bacher-Stier, C., Santiuste, M. and Pennell, D.J.
Journal of the American College of Cardiology 76
(13): 1536-1547.
29 September 2020
DeepWAS: multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.
Arloth, J., Eraslan, G., Andlauer, T.F.M., Martins, J., Iurato, S., Kühnel, B., Waldenberger, M., Frank, J., Gold, R., Hemmer, B., Luessi, F., Nischwitz, S., Paul, F., Wiendl, H., Gieger, C., Heilmann-Heimbach, S., Kacprowski, T., Laudes, M., Meitinger, T., Peters, A., Rawal, R., Strauch, K., Lucae, S., Müller-Myhsok, B., Rietschel, M., Theis, F.J., Binder, E.B. and Mueller, N.S.
PLoS Computational Biology 16
(2): e1007616.
3 February 2020
Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. and Treese, C.
Clinical and Translational Oncology 22
(12): 2357-2363.
December 2020
Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling.
Asaro, A., Carlo-Spiewok, A.S., Malik, A.R., Rothe, M., Schipke, C.G., Peters, O., Heeren, J. and Willnow, T.E.
Alzheimer's & Dementia 16
(9): 1248-1258.
September 2020
Prodromal headache in MOG-antibody positive optic neuritis.
Asseyer, S., Hamblin, J., Messina, S., Mariano, R., Siebert, N., Everett, R., Küker, W., Bellmann-Strobl, J., Ruprecht, K., Jarius, S., Leite, M.I., Brandt, A., Paul, F. and Palace, J.
Multiple Sclerosis and Related Disorders 40
: 101965.
May 2020
Ventral posterior nucleus volume is associated with neuropathic pain intensity in neuromyelitis optica spectrum disorders.
Asseyer, S., Kuchling, J., Gaetano, L., Komnenić, D., Siebert, N., Chien, C., Scheel, M., Oertel, F.C., Ruprecht, K., Bellmann-Strobl, J., Finke, C., Chakravarty, M.M., Magon, S., Wuerfel, J., Paul, F., Papadopoulou, A. and Brandt, A.U.
Multiple Sclerosis and Related Disorders 46
: 102579.
November 2020
Wisdom of the expert crowd prediction of response for 3 neurology randomized trials.
Atanasov, P., Diamantaras, A., MacPherson, A., Vinarov, E., Benjamin, D.M., Shrier, I., Paul, F., Dirnagl, U. and Kimmelman, J.
Neurology 95
(5): e488-e498.
4 August 2020
Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and tetralogy of fallot and its functional evaluation in the Drosophila heart.
Auxerre-Plantié, E., Nielsen, T., Grunert, M., Olejniczak, O., Perrot, A., Özcelik, C., Harries, D., Matinmehr, F., Dos Remedios, C., Mühlfeld, C., Kraft, T., Bodmer, R., Vogler, G. and Sperling, S.R.
Disease Models & Mechanisms 13
(12): dmm045377.
18 December 2020
Loss of m(1)acp(3)Ψ ribosomal RNA modification is a major feature of cancer.
Babaian, A., Rothe, K., Girodat, D., Minia, I., Djondovic, S., Milek, M., Spencer Miko, S.E., Wieden, H.J., Landthaler, M., Morin, G.B. and Mager, D.L.
Cell Reports 31
(5): 107611.
5 May 2020
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.
Baccin, C., Al-Sabah, J., Velten, L., Helbling, P.M., Grünschläger, F., Hernández-Malmierca, P., Nombela-Arrieta, C., Steinmetz, L.M., Trumpp, A. and Haas, S.
Nature Cell Biology 22
(1): 38-48.
January 2020
Cortical topological network changes following optic neuritis.
Backner, Y., Ben-Shalom, I., Kuchling, J., Siebert, N., Scheel, M., Ruprecht, K., Brandt, A., Paul, F. and Levin, N.
Neurology Neuroimmunology & Neuroinflammation 7
(3): e687.
May 2020
Suppression of β1-adrenoceptor autoantibodies is involved in the antiarrhythmic effects of omega-3 fatty acids in male and female hypertensive rats.
Bacova, B.S., Radosinska, J., Wallukat, G., Barancik, M., Wallukat, A., Knezl, V., Sykora, M., Paulis, L. and Tribulova, N.
International Journal of Molecular Sciences 21
(2): 526.
14 January 2020
Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease.
Bader, J.M., Geyer, P.E., Müller, J.B., Strauss, M.T., Koch, M., Leypoldt, F., Koertvelyessy, P., Bittner, D., Schipke, C.G., Incesoy, E.I., Peters, O., Deigendesch, N., Simons, M., Jensen, M.K., Zetterberg, H. and Mann, M.
Molecular Systems Biology 16
(6): e9356.
1 June 2020
ACE2 - das missbrauchte Multitalent [ACE2 - the hijacked all-rounder].
Bader, M.
Nephrologe 15
(6): 375-380.
November 2020
Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study.
Bahr, L.S., Bock, M., Liebscher, D., Bellmann-Strobl, J., Franz, L., Prüß, A., Schumann, D., Piper, S.K., Kessler, C.S., Steckhan, N., Michalsen, A., Paul, F. and Mähler, A.
Trials 21
(1): 3.
2 January 2020
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey, M.H., Meyerson, W.U., Dursi, L.J., Wang, L.B., Dong, G., Liang, W.W., Weerasinghe, A., Li, S., Li, Y., Kelso, S., Saksena, G., Ellrott, K., Wendl, M.C., Wheeler, D.A., Getz, G., Simpson, J.T., Gerstein, M.B. and Ding, Li
Nature Communications 11
(1): 4748.
21 September 2020
SuperCYPsPred - a web server for the prediction of cytochrome activity.
Banerjee, P., Dunkel, M., Kemmler, E. and Preissner, R.
Nucleic Acids Research 48
(W1): W580-W585.
July 2020
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Barone, M., Müller, M., Chiha, S., Ren, J., Albat, D., Soicke, A., Dohmen, S., Klein, M., Bruns, J., van Dinther, M., Opitz, R., Lindemann, P., Beerbaum, M., Motzny, K., Roske, Y., Schmieder, P., Volkmer, R., Nazaré, M., Heinemann, U., Oschkinat, H., Ten Dijke, P., Schmalz, H.G. and Kühne, R.
Proceedings of the National Academy of Sciences of the United States of America 117
(47): 29684-29690.
24 November 2020
Darm-Herz-Achse: Wie Darmbakterien kardiovaskuläre
Erkrankungen beeinflussen [Gut-heart axis: how gut bacteria influence cardiovascular diseases].
Bartolomaeus, H., McParland, V. and Wilck, N.
Herz 45
(2): 134-141.
April 2020
Induction and analysis of oxidative stress in Sleeping Beauty transposon-transfected human retinal pigment epithelial cells.
Bascuas, T., Kropp, M., Harmening, N., Asrih, M., Izsvák, Z. and Thumann, G.
Journal of Visualized Experiments 2020
(166): e61957.
11 December 2020
Enhancement of CRISPR-Cas9 induced precise gene editing by targeting Histone H2A-K15 ubiquitination.
Bashir, S., Dang, T., Rossius, J., Wolf, J. and Kuehn, R.
BMC Biotechnology 20
(1): 57.
23 October 2020
Unblending of transcriptional condensates in human repeat expansion disease.
Basu, S., Mackowiak, S.D., Niskanen, H., Knezevic, D., Asimi, V., Grosswendt, S., Geertsema, H., Ali, S., Jerković, I., Ewers, H., Mundlos, S., Meissner, A., Ibrahim, D.M. and Hnisz, D.
Cell 181
(5): 1062-1079.
28 May 2020
Linescan microscopy data to extract diffusion coefficient of a fluorescent species using a commercial confocal microscope.
Bathe-Peters, M., Gmach, P., Annibale, P. and Lohse, M.J.
Data in Brief 29
: 105063.
April 2020
Paternal exercise protects against liver steatosis in the male offspring of mice submitted to high fat diet.
Batista, R.O., Budu, A., Alves-Silva, T., Arakaki, A.M., Gregnani, M.F.S., Rodrigues Húngaro, T.G., Burgos-Silva, M., Wasinski, F., Lanzoni, V.P., Camara, N.O.S., Oyama, L.M., Bader, M. and Araújo, R.C.
Life Sciences 263
: 118583.
15 December 2020
Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia.
Becker, H., Pfeifer, D., Ihorst, G., Pantic, M., Wehrle, J., Rüter, B.H., Bullinger, L., Hackanson, B., Germing, U., Kuendgen, A., Platzbecker, U., Döhner, K., Ganser, A., Hagemeijer, A., Wijermans, P.W., Döhner, H., Duyster, J. and Lübbert, M.
Annals of Hematology 99
(7): 1551-1560.
July 2020
Fast myocardial T(1) mapping using cardiac motion correction.
Becker, K.M., Blaszczyk, E., Funk, S., Nuesslein, A., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Magnetic Resonance in Medicine 83
(2): 438-451.
February 2020
Genetic information from discordant sibling pairs points to ESRP2 as a candidate trans-acting regulator of the CF modifier gene SCNN1B.
Becker, T., Pich, A., Tamm, S., Hedtfeld, S., Ibrahim, M., Altmüller, J., Dalibor, N., Toliat, M.R., Janciauskiene, S., Tümmler, B. and Stanke, F.
Scientific Reports 10
(1): 22447.
31 December 2020
Species-specific differences in synaptic transmission and plasticity.
Beed, P., Ray, S., Velasquez, L.M., Stumpf, A., Parthier, D., Swaminathan, A., Nitzan, N., Breustedt, J., Las, L., Brecht, M. and Schmitz, D.
Scientific Reports 10
(1): 16557.
6 October 2020
Layer 3 pyramidal cells in the medial entorhinal cortex orchestrate up-down states and entrain the deep layers differentially.
Beed, P., de Filippo, R., Holman, C., Johenning, F.W., Leibold, C., Caputi, A., Monyer, H. and Schmitz, D.
Cell Reports 33
(10): 108470.
8 December 2020
Disentangling pro-mitotic signaling during cell cycle progression using time-resolved single-cell imaging.
Benary, M., Bohn, S., Lüthen, M., Nolis, I.K., Blüthgen, N. and Loewer, A.
Cell Reports 31
(2): 107514.
14 April 2020
Assessment of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids, in patients with persistent atrial fibrillation: rationale and design of the PROMISE-AF phase II study.
Berlin, S., Goette, A., Summo, L., Lossie, J., Gebauer, A., Al-Saady, N., Calo, L., Naccarelli, G., Schunck, W.H., Fischer, R., Camm, A.J. and Dobrev, D.
International Journal of Cardiology (IJC) Heart & Vasculature 29
: 100573.
August 2020
Conduction delays in the visual pathways of progressive multiple sclerosis patients covary with brain structure.
Berman, S., Backner, Y., Krupnik, R., Paul, F., Petrou, P., Karussis, D., Levin, N. and Mezer, A.A.
NeuroImage 221
: 117204.
1 November 2020
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19.
Bernardes, J.P., Mishra, N., Tran, F., Bahmer, T., Best, L., Blase, J.I., Bordoni, D., Franzenburg, J., Geisen, U., Josephs-Spaulding, J., Köhler, P., Künstner, A., Rosati, E., Aschenbrenner, A.C., Bacher, P., Baran, N., Boysen, T., Brandt, B., Bruse, N., Dörr, J., Dräger, A., Elke, G., Ellinghaus, D., Fischer, J., Forster, M., Franke, A., Franzenburg, S., Frey, N., Friedrichs, A., Fuß, J., Glück, A., Hamm, J., Hinrichsen, F., Hoeppner, M.P., Imm, S., Junker, R., Kaiser, S., Kan, Y.H., Knoll, R., Lange, C., Laue, G., Lier, C., Lindner, M., Marinos, G., Markewitz, R., Nattermann, J., Noth, R., Pickkers, P., Rabe, K.F., Renz, A., Röcken, C., Rupp, J., Schaffarzyk, A., Scheffold, A., Schulte-Schrepping, J., Schunk, D., Skowasch, D., Ulas, T., Wandinger, K.P., Wittig, M., Zimmermann, J., Busch, H., Hoyer, B.F., Kaleta, C., Heyckendorf, J., Kox, M., Rybniker, J., Schreiber, S., Schultze, J.L. and Rosenstiel, P.
Immunity 53
(6): 1296-1314.
15 December 2020
Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer.
Berndt, N., Egners, A., Mastrobuoni, G., Vvedenskaya, O., Fragoulis, A., Dugourd, A., Bulik, S., Pietzke, M., Bielow, C., van Gassel, R., Olde Damink, S.W., Erdem, M., Saez-Rodriguez, J., Holzhütter, H.G., Kempa, S. and Cramer, T.
British Journal of Cancer 122
(2): 233-244.
21 January 2020
SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
Biederstädt, A., Hassan, Z., Schneeweis, C., Schick, M., Schneider, L., Muckenhuber, A., Hong, Y., Siegers, G., Nilsson, L., Wirth, M., Dantes, Z., Steiger, K., Schunck, K., Langston, S., Lenhof, H.P., Coluccio, A., Orben, F., Slawska, J., Scherger, A., Saur, D., Müller, S., Rad, R., Weichert, W., Nilsson, J., Reichert, M., Schneider, G. and Keller, U.
Gut 69
(8): 1472-1482.
August 2020
Normal-range urinary albumin excretion associates with blood pressure and renal electrolyte handling in pregnancy.
Birukov, A., Andersen, M.S., Jørgensen, J.S., Kitlen, G., Rakova, N., Nielsen, J.H., Andersen, L.B., Dechend, R. and Jensen, B.L.
American Journal of Physiology Renal Physiology 319
(1): F1-F7.
July 2020
Blood pressure and angiogenic markers in pregnancy: contributors to pregnancy-induced hypertension and offspring cardiovascular risk.
Birukov, A.., Herse, F., Nielsen, J.H., Kyhl, H.B., Golic, M., Kräker, K., Haase, N., Busjahn, A., Bruun, S., Jensen, B.L., Müller, D.N., Jensen, T.K., Christesen, H.T., Andersen, M.S., Jørgensen, J.S., Dechend, R. and Andersen, L.B.
Hypertension 76
(3): 901-909.
September 2020
Clinical implications of serum neurofilament in newly diagnosed MS patients: a longitudinal multicentre cohort study.
Bittner, S., Steffen, F., Uphaus, T., Muthuraman, M., Fleischer, V., Salmen, A., Luessi, F., Berthele, A., Klotz, L., Meuth, S.G., Bayas, A., Paul, F., Hartung, H.P., Linker, R., Heesen, C., Stangel, M., Wildemann, B., Then Bergh, F., Tackenberg, B., Kuempfel, T., Weber, F., Zettl, U.K., Ziemann, U., Tumani, H., Groppa, S., Mühlau, M., Lukas, C., Hemmer, B., Wiendl, H., Gold, R. and Zipp, F.
EBioMedicine 56
: 102807.
June 2020
Evaluation of the 'ring sign' and the 'core sign' as a magnetic resonance imaging marker of disease activity and progression in clinically isolated syndrome and early multiple sclerosis.
Blindenbacher, N., Brunner, E., Asseyer, S., Scheel, M., Siebert, N., Rasche, L., Bellmann-Strobl, J., Brandt, A., Ruprecht, K., Meier, D., Wuerfel, J., Paul, F. and Sinnecker, T.
Multiple Sclerosis Journal Experimental Translational and Clinical 6
(1): 2055217320915480.
30 March 2020
Investigating APOE, APP-Aβ metabolism genes and Alzheimer's disease GWAS hits in brain small vessel ischemic disease.
Blumenau, S., Foddis, M., Müller, S., Holtgrewe, M., Bentele, K., Berchtold, D., Beule, D., Dirnagl, U. and Sassi, C.
Scientific Reports 10
(1): 7103.
28 April 2020
Optical mapping of cAMP signaling at the nanometer scale.
Bock, A., Annibale, P., Konrad, C., Hannawacker, A., Anton, S.E., Maiellaro, I., Zabel, U., Sivaramakrishnan, S., Falcke, M. and Lohse, M.J.
Cell 182
(6): 1519-1530.
17 September 2020
Heart-specific immune responses in an animal model of autoimmune-related myocarditis mitigated by an immunoproteasome inhibitor and genetic ablation.
Bockstahler, M., Fischer, A., Goetzke, C.C., Neumaier, H.L., Sauter, M., Kespohl, M., Müller, A.M., Meckes, C., Salbach, C., Schenk, M., Heuser, A., Landmesser, U., Weiner, J., Meder, B., Lehmann, L., Kratzer, A., Klingel, K., Katus, H.A., Kaya, Z. and Beling, A.
Circulation 141
(23): 1885-1902.
9 June 2020
Cardiorenal sodium MRI in small rodents using a quadrature birdcage volume resonator at 9.4 T.
Boehmert, L., Waiczies, H., Kuehne, A., Oezerdem, C., Waiczies, S., Starke, L., Ku, M.C., Pohlmann, A., Seeliger, E. and Niendorf, T.
Magnetic Resonance Materials in Physics Biology and Medicine 33
(1): 121-130.
February 2020
Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis.
Bogdanow, B., Schmidt, M., Weisbach, H., Gruska, I., Vetter, B., Imami, K., Ostermann, E., Brune, W., Selbach, M., Hagemeier, C. and Wiebusch, L.
Nature Communications 11
(1): 4845.
24 September 2020
VISOR: a versatile haplotype-aware structural variant simulator for short- and long-read sequencing.
Bolognini, D., Sanders, A., Korbel, J.O., Magi, A., Benes, V. and Rausch, T.
Bioinformatics 36
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15 February 2020
Oxidative metabolism drives immortalization of neural stem cells during tumorigenesis.
Bonnay, F., Veloso, A., Steinmann, V., Köcher, T., Abdusselamoglu, M.D., Bajaj, S., Rivelles, E., Landskron, L., Esterbauer, H., Zinzen, R.P. and Knoblich, J.A.
Cell 182
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17 September 2020
Altered glycosylation contributes to placental dysfunction upon early disruption of the NK cell-DC dynamics.
Borowski, S., Tirado-Gonzalez, I., Freitag, N., Garcia, M.G., Barrientos, G. and Blois, S.M.
Frontiers in Immunology 11
: 1316.
14 July 2020
Effects of dietary protein-load and alkaline supplementation on acid-base balance and glucose metabolism in healthy elderly.
Boschmann, M., Kaiser, N., Klasen, A., Klug, L., Mähler, A., Michalsen, A., Vormann, J., Werner, T. and Stange, R.
European Journal of Clinical Nutrition 74
: 48-56.
August 2020
An activatable lanthanide luminescent probe for time-gated detection of nitroreductase in live bacteria.
Brennecke, B., Wang, Q., Zhang, Q., Hu, H.Y. and Nazaré, M.
Angewandte Chemie International Edition 59
(22): 8512-8516.
25 May 2020
iPSC modeling of RBM20-deficient DCM identifies upregulation of RBM20 as a therapeutic strategy.
Briganti, F., Sun, H., Wei, W., Wu, J., Zhu, C., Liss, M., Karakikes, I., Rego, S., Cipriano, A., Snyder, M., Meder, B., Xu, Z., Millat, G., Gotthardt, M., Mercola, M. and Steinmetz, L.M.
Cell Reports 32
(10): 108117.
8 September 2020
Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial.
Bröckelmann, P.J., Goergen, H., Keller, U., Meissner, J., Ordemann, R., Halbsguth, T.V., Sasse, S., Sökler, M., Kerkhoff, A., Mathas, S., Hüttmann, A., Bormann, M., Zimmermann, A., Mettler, J., Fuchs, M., von Tresckow, B., Baues, C., Rosenwald, A., Klapper, W., Kobe, C., Borchmann, P. and Engert, A.
JAMA Oncology 6
(6): 872-880.
June 2020
Comprehensive molecular analysis of 61 Egyptian families with hereditary nonsyndromic hearing loss.
Budde, B.S., Aly, M.A., Mohamed, M.R., Breß, A., Altmüller, J., Motameny, S., Kawalia, A., Thiele, H., Konrad, K., Becker, C., Toliat, M.R., Nürnberg, G., Sayed, E.A.F., Mohamed, E.S., Pfister, M. and Nürnberg, P.
Clinical Genetics 98
(1): 32-42.
July 2020
Genomic rewiring of SOX2 chromatin interaction network during differentiation of ESCs to postmitotic neurons.
Bunina, D., Abazova, N., Diaz, N., Noh, K.M., Krijgsveld, J. and Zaugg, J.B.
Cell Systems 10
(6): 480-494.
24 June 2020
Vitamin D and disease severity in multiple sclerosis-baseline data from the randomized controlled trial (EVIDIMS).
Bäcker-Koduah, P., Bellmann-Strobl, J., Scheel, M., Wuerfel, J., Wernecke, K.D., Dörr, J., Brandt, A.U. and Paul, F.
Frontiers in Neurology 11
: 129.
25 February 2020
Effect of vitamin D supplementation on N-glycan branching and cellular immunophenotypes in MS.
Bäcker-Koduah, P., Infante-Duarte, C., Ivaldi, F., Uccelli, A., Bellmann-Strobl, J., Wernecke, K.D., Sy, M., Demetriou, M., Dörr, J., Paul, F. and Brandt, A.U.
Annals of Clinical and Translational Neurology 7
(9): 1628-1641.
September 2020
Prediction of birth weight small for gestational age with and without preeclampsia by angiogenic markers: an Odense Child Cohort Study.
Bækgaard Thorsen, L.H., Bjørkholt Andersen, L., Birukov, A., Lykkedegn, S., Dechend, R., Stener Jørgensen, J. and Thybo Christesen, H.
Journal of Maternal-Fetal & Neonatal Medicine 33
(8): 1377-1384.
April 2020
NF-κB signaling in tanycytes mediates inflammation-induced anorexia.
Böttcher, M., Müller-Fielitz, H., Sundaram, S.M., Gallet, S., Neve, V., Shionoya, K., Zager, A., Quan, N., Liu, X., Schmidt-Ullrich, R., Haenold, R., Wenzel, J., Blomqvist, A., Engblom, D., Prevot, V. and Schwaninger, M.
Molecular Metabolism 39
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September 2020
Human and mouse essentiality screens as a resource for disease gene discovery.
Cacheiro, P., Muñoz-Fuentes, V., Murray, S.A., Dickinson, M.E., Bucan, M., Nutter, L.M.J., Peterson, K.A., Haselimashhadi, H., Flenniken, A.M., Morgan, H., Westerberg, H., Konopka, T., Hsu, C.W., Christiansen, A., Lanza, D.G., Beaudet, A.L., Heaney, J.D., Fuchs, H., Gailus-Durner, V., Sorg, T., Prochazka, J., Novosadova, V., Lelliott, C.J., Wardle-Jones, H., Wells, S., Teboul, L., Cater, H., Stewart, M., Hough, T., Wurst, W., Sedlacek, R., Adams, D.J., Seavitt, J.R., Tocchini-Valentini, G., Mammano, F., Braun, R.E., McKerlie, C., Herault, Y., de Angelis, M.H., Mallon, A.M., Lloyd, K.C.K., Brown, S.D.M., Parkinson, H., Meehan, T.F. and Smedley, D.
Nature Communications 11
(1): 655.
31 January 2020
Real-time visualization of titin dynamics reveals extensive reversible photobleaching in human induced pluripotent stem cell-derived cardiomyocytes.
Cadar, A.G., Feaster, T.K., Bersell, K.R., Wang, L., Hong, T.T., Balsamo, J.A., Zhang, Z., Chun, Y.W., Nam, Y.J., Gotthardt, M., Knollmann, B.C., Roden, D.M., Lim, C.C. and Hong, C.C.
American Journal of Physiology Cell Physiology 318
(1): C163-C173.
January 2020
Genomic basis for RNA alterations in cancer.
Calabrese, C., Davidson, N.R., Demircioğlu, D., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., Soulette, C.M., Urban, L., Greger, L., Li, S., Liu, D., Perry, M.D., Xiang, Q., Zhang, F., Zhang, J., Bailey, P., Erkek, S., Hoadley, K.A., Hou, Y., Huska, M.R., Kilpinen, H., Korbel, J.O., Marin, M.G., Markowski, J., Nandi, T., Pan-Hammarström, Q., Pedamallu, C.S., Siebert, R., Stark, S.G., Su, H., Tan, P., Waszak, S.M., Yung, C., Zhu, S., Awadalla, P., Creighton, C.J., Meyerson, M., Ouellette, B.F.F., Wu, K., Yang, H., Brazma, A., Brooks, A.N., Göke, J., Rätsch, G., Schwarz, R.F., Stegle, O. and Zhang, Z.
Nature 578
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6 February 2020
Quantification of translation uncovers the functions of the alternative transcriptome.
Calviello, L., Hirsekorn, A. and Ohler, U.
Nature Structural & Molecular Biology 27
(8): 717-725.
August 2020
Single-cell lineage tracing approaches in hematology research: technical considerations.
Carrelha, J., Lin, D.S., Rodriguez-Fraticelli, A.E., Luis, T.C., Wilkinson, A.C., Cabezas-Wallscheid, N., Tremblay, C.S. and Haas, S.
Experimental Hematology 89
: 26-36.
September 2020
Control of neutrophil influx during peritonitis by transcriptional cross-regulation of chemokine CXCL1 by IL-17 and IFN-γ.
Catar, R.A., Chen, L., Cuff, S.M., Kift-Morgan, A., Eberl, M., Kettritz, R., Kamhieh-Milz, J., Moll, G., Li, Q., Zhao, H., Kawka, E., Zickler, D., Parekh, G., Davis, P., Fraser, D.J., Dragun, D., Eckardt, K.U., Jörres, A. and Witowski, J.
Journal of Pathology 251
(2): 175-186.
June 2020
Impact of treatment on cellular immunophenotype in MS: a cross-sectional study.
Cellerino, M., Ivaldi, F., Pardini, M., Rotta, G., Vila, G., Bäcker-Koduah, P., Berge, T., Laroni, A., Lapucci, C., Novi, G., Boffa, G., Sbragia, E., Palmeri, S., Asseyer, S., Høgestøl, E., Campi, C., Piana, M., Inglese, M., Paul, F., Harbo, H.F., Villoslada, P., Kerlero de Rosbo, N. and Uccelli, A.
Neurology Neuroimmunology & Neuroinflammation 7
(3): e693.
May 2020
Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils.
Cerofolini, L., Ravera, E., Bologna, S., Wiglenda, T., Böddrich, A., Purfürst, B., Benilova, I., Korsak, M., Gallo, G., Rizzo, D., Gonnelli, L., Fragai, M., De Strooper, B., Wanker, E.E. and Luchinat, C.
Chemical Communications 56
(62): 8830-8833.
11 August 2020
Visual system damage and network maladaptation are associated with cognitive performance in neuromyelitis optica spectrum disorders.
Chavarro, V.S., Bellmann-Strobl, J., Zimmermann, H.G., Scheel, M., Chien, C., Oertel, F.C., Weygandt, M., Ruprecht, K., Paul, F., Finke, C. and Brandt, A.U.
Multiple Sclerosis and Related Disorders 45
: 102406.
October 2020
Longitudinal ultra-high field MRI of brain lesions in neuromyelitis optica spectrum disorders.
Chawla, S., Ge, Y., Wuerfel, J., Asadollahi, S., Mohan, S., Paul, F., Sinnecker, T. and Kister, I.
Multiple Sclerosis and Related Disorders 42
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July 2020
Structure of RyR1 in native membranes.
Chen, W. and Kudryashev, M.
EMBO Reports 21
(5): e49891.
6 May 2020
A dynamic folded hairpin conformation is associated with α-globin activation in erythroid cells.
Chiariello, A.M., Bianco, S., Oudelaar, A M., Esposito, A., Annunziatella, C., Fiorillo, L., Conte, M., Corrado, A., Prisco, A., Larke, M.S.C., Telenius, J.M., Sciarretta, R., Musella, F., Buckle, V.J., Higgs, D.R., Hughes, J.R. and Nicodemi, M.
Cell Reports 30
(7): 2125-2135.
18 February 2020
Considerations for mean upper cervical cord area implementation in a longitudinal MRI setting: methods, interrater reliability, and MRI quality control.
Chien, C., Juenger, V., Scheel, M., Brandt, A.U. and Paul, F.
American Journal of Neuroradiology 41
(2): 343-350.
1 February 2020
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chong, C., Müller, M., Pak, H.S., Harnett, D., Huber, F., Grun, D., Leleu, M., Auger, A., Arnaud, M., Stevenson, B.J., Michaux, J., Bilic, I., Hirsekorn, A., Calviello, L., Simó-Riudalbas, L., Planet, E., Lubiński, J., Bryśkiewicz, M., Wiznerowicz, M., Xenarios, I., Zhang, L., Trono, D., Harari, A., Ohler, U., Coukos, G. and Bassani-Sternberg, M.
Nature Communications 11
(1): 1293.
10 March 2020
Structure of the active GGEEF domain of a diguanylate cyclase from Vibrio cholerae.
Chouhan, O.P., Roske, Y., Heinemann, U. and Biswas, S.
Biochemical and Biophysical Research Communications 523
(2): 287-292.
5 March 2020
LRP2 controls sonic hedgehog-dependent differentiation of cardiac progenitor cells during outflow tract formation.
Christ, A., Marczenke, M. and Willnow, T.E.
Human Molecular Genetics 29
(19): 3183-3196.
1 October 2020
A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort.
Christakoudi, S., Tsilidis, K.K., Muller, D.C., Freisling, H., Weiderpass, E., Overvad, K., Söderberg, S., Häggström, C., Pischon, T., Dahm, C.C., Zhang, J., Tjønneland, A., Halkjær, J., MacDonald, C., Boutron-Ruault, M.C., Mancini, F.R., Kühn, T., Kaaks, R., Schulze, M.B., Trichopoulou, A., Karakatsani, A., Peppa, E., Masala, G., Pala, V., Panico, S., Tumino, R., Sacerdote, C., Quirós, J.R., Agudo, A., Sánchez, M.J., Cirera, L., Barricarte-Gurrea, A., Amiano, P., Memarian, E., Sonestedt, E., Bueno-de-Mesquita, B., May, A.M., Khaw, K.T., Wareham, N.J., Tong, T.Y.N., Huybrechts, I., Noh, H., Aglago, E.K., Ellingjord-Dale, M., Ward, H.A., Aune, D. and Riboli, E.
Scientific Reports 10
(1): 14541.
3 September 2020
Intron with transgenic marker (InTraM) facilitates high-throughput screening of endogenous gene reporter lines.
Collins, R.T., Coxam, B., Fechner, I., Unterweger, I., Szymborska, A., Meier, K. and Gerhardt, H.
Genesis 58
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November 2020
Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing.
Conrad, T., Ntini, E., Lang, B., Cozzuto, L., Andersen, J.B., Marquardt, J.U., Ponomarenko, J., Tartaglia, G.G. and Vang Orom, U.A.
RNA 26
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November 2020
Maximizing transcription of nucleic acids with efficient T7 promoters.
Conrad, T., Plumbom, I., Alcobendas, M., Vidal, R. and Sauer, S.
Communications Biology 3
(1): 439.
14 August 2020
Polymer physics indicates chromatin folding variability across single-cells results from state degeneracy in phase separation.
Conte, M., Fiorillo, L., Bianco, S., Chiariello, A.M., Esposito, A. and Nicodemi, M.
Nature Communications 11
(1): 3289.
3 July 2020
Quantitative multi-parameter mapping optimized for the clinical routine.
Cooper, G., Hirsch, S., Scheel, M., Brandt, A.U., Paul, F., Finke, C., Boehm-Sturm, P. and Hetzer, S.
Frontiers in Neuroscience 14
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7 December 2020
Endothelial damage and dysfunction in acute graft-versus-host disease.
Cordes, S., Mokhtari, Z., Bartosova, M., Mertlitz, S., Riesner, K., Shi, Y., Mengwasser, J., Kalupa, M., McGeary, A., Schleifenbaum, J., Schrezenmeier, J., Bullinger, L., Diaz-Ricart, M., Palomo, M., Carrreras, E., Beutel, G., Schmitt, C.P., Beilhack, A. and Penack, O.
Haematologica 106
(8): 2147-2160.
1 August 2020
A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis.
Coscia, F., Doll, S., Bech, J.M., Schweizer, L., Mund, A., Lengyel, E., Lindebjerg, J., Madsen, G.I., Moreira, J.M. and Mann, M.
Journal of Pathology 251
(1): 100-112.
May 2020
Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription.
Cossa, G., Roeschert, I., Prinz, F., Baluapuri, A., Silveira Vidal, R., Schülein-Völk, C., Chang, Y.C., Ade, C.P., Mastrobuoni, G., Girard, C., Kumar, A., Wortmann, L., Walz, S., Lührmann, R., Kempa, S., Kuster, B., Wolf, E., Mumberg, D. and Eilers, M.
Molecular Cell 77
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19 March 2020
A specialized niche in the pancreatic microenvironment promotes endocrine differentiation.
Cozzitorto, C., Mueller, L., Ruzittu, S., Mah, N., Willnow, D., Darrigrand, J.F., Wilson, H., Khosravinia, D., Mahmoud, A.A., Risolino, M., Selleri, L. and Spagnoli, F.M.
Developmental Cell 55
(2): 150-162.
26 October 2020
Short-term western diet aggravates non-alcoholic fatty liver disease (NAFLD) with portal hypertension in TGR(mREN2)27 rats.
Cremonese, C., Schierwagen, R., Uschner, F.E., Torres, S., Tyc, O., Ortiz, C., Schulz, M., Queck, A., Kristiansen, G., Bader, M., Sauerbruch, T., Weiskirchen, R., Walther, T., Trebicka, J. and Klein, S.
International Journal of Molecular Sciences 21
(9): 3308.
1 May 2020
Revalorization of bioactive compounds from tropical fruit by-products and industrial applications by means of sustainable approaches.
Cádiz-Gurrea, M.L., Villegas-Aguilar, M.C., Leyva-Jiménez, F.J., Pimentel-Moral, S., Fernández-Ochoa, Á., Alañón, M.E. and Segura-Carretero, A.
Food Research International 138
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December 2020
Diagnostic procedures in suspected attacks in patients with neuromyelitis optica spectrum disorders: results of an international survey.
D'Souza, M., Papadopoulou, A., Levy, M., Jacob, A., Yeaman, M.R., Kümpfel, T., Marignier, R., Paul, F. and Brandt, A.U.
Multiple Sclerosis and Related Disorders 41
: 102027.
June 2020
Restoring treatment response in colorectal cancer cells by targeting MACC1-dependent ABCB1 expression in combination therapy.
Dahlmann, M., Werner, R., Kortüm, B., Kobelt, D., Walther, W. and Stein, U.
Frontiers in Oncology 10
: 599.
23 April 2020
Novel targets of protoporphyrin-IX determined by gene expression analysis.
Dai, Y. and Kemmner, W.
International Journal of Clinical Oncology and Cancer Research 5
(3): 56-64.
September 2020
The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel, B., Czimmerer, Z., Halasz, L., Boto, P., Kolostyak, Z., Poliska, S., Berger, W.K., Tzerpos, P., Nagy, G., Horvath, A., Hajas, G., Cseh, T., Nagy, A., Sauer, S., Francois-Deleuze, J., Szatmari, I., Bacsi, A. and Nagy, L.
Genes & Development 34
(21-22): 1474-1492.
1 November 2020
The pierced lasso topology leptin has a bolt on dynamic domain composed by the disordered loops I and III.
Danielsson, J., Noel, J.K., Simien, J.M., Duggan, B.M., Oliveberg, M., Onuchic, J.N., Jennings, P.A. and Haglund, E.
Journal of Molecular Biology 432
(9): 3050-3063.
17 April 2020
TIM-3 and CEACAM1 do not interact in cis and in trans.
De Sousa Linhares, A., Kellner, F., Jutz, S., Zlabinger, G.J., Gabius, H.J., Huppa, J.B., Leitner, J. and Steinberger, P.
European Journal of Immunology 50
(8): 1126-1141.
August 2020
PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V., Berruezo-Llacuna, M., Altwasser, R., Winkler, W., Sundaravinayagam, D., Balasubramanian, S., Caganova, M., Graf, R., Rahjouei, A., Henke, M.T., Driesner, M., Keller, L., Prigione, A., Janz, M., Akalin, A. and Di Virgilio, M.
Journal of Experimental Medicine 217
(10): e20200137.
5 October 2020
Cyclin-dependent kinase 18 controls trafficking of
aquaporin-2 and its abundance through ubiquitin
ligase STUB1, which functions as an AKAP.
Dema, A., Faust, D., Lazarow, K., Wippich, M., Neuenschwander, M., Zühlke, K., Geelhaar, A., Pallien, T., Hallscheidt, E., Eichhorst, J., Wiesner, B., Cernecká, H., Popp, O., Mertins, P., Dittmar, G., von Kries, J.P. and Klussmann, E.
Cells 9
(3): 673.
10 March 2020
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P., Newman, A.G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., Kleinau, G., Derkow, K., Richard, B.C., Schipke, C., Scheidereit, C., Stachelscheid, H., Golenbock, D., Peters, O., Coleman, M., Heppner, F.L., Scheerer, P., Tarabykin, V., Ruprecht, K., Izsvák, Z., Mayer, J. and Lehnardt, S.
JCI Insight 5
(7): e131093.
9 April 2020
Reproducibility of heart rate variability revealed by repeated measurements during and after hemodialysis.
Deussing, K., Wendt, R., Burger, R., Gollasch, M. and Beige, J.
Blood Purification 49
(3): 356-363.
May 2020
RNA-sequencing and somatic mutation status of adrenocortical tumors: novel pathogenetic insights.
Di Dalmazi, G., Altieri, B., Scholz, C., Sbiera, S., Luconi, M., Waldman, J., Kastelan, D., Ceccato, F., Chiodini, I., Arnaldi, G., Riester, A., Osswald, A., Beuschlein, F., Sauer, S., Fassnacht, M., Appenzeller, S. and Ronchi, C.L.
Journal of Clinical Endocrinology & Metabolism 105
(12): dgaa616.
December 2020
Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.
Dias D'Andréa, E., Roske, Y., de Oliveira, G.A.P., Cremer, N., Diehl, A., Schmieder, P., Heinemann, U., Oschkinat, H. and Ricardo Pires, J.
Journal of Structural Biology 211
(2): 107536.
1 August 2020
Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.
Dietrich, M., Koska, V., Hecker, C., Göttle, P., Hilla, A.M., Heskamp, A., Lepka, K., Issberner, A., Hallenberger, A., Baksmeier, C., Steckel, J., Balk, L., Knier, B., Korn, T., Havla, J., Martínez-Lapiscina, E.H., Solà-Valls, N., Manogaran, P., Olbert, E.D., Schippling, S., Cruz-Herranz, A., Yiu, H., Button, J., Caldito, N.G., von Gall, C., Mausberg, A.K., Stettner, M., Zimmermann, H.G., Paul, F., Brandt, A.U., Küry, P., Goebels, N., Aktas, O., Berndt, C., Saidha, S., Green, A.J., Calabresi, P.A., Fischer, D., Hartung, H.P. and Albrecht, P.
Brain 143
(4): 1127-1142.
April 2020
Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation.
Dimchev, G., Amiri, B., Humphries, A.C., Schaks, M., Dimchev, V., Stradal, T.E.B., Faix, J., Krause, M., Way, M., Falcke, M. and Rottner, K.
Journal of Cell Science 133
(7): jcs239020.
9 April 2020
Novel loss-of-function variants in CDC14A are associated with recessive sensorineural hearing loss in Iranian and Pakistani patients.
Doll, J., Kolb, S., Schnapp, L., Rad, A., Rüschendorf, F., Khan, I., Adli, A., Hasanzadeh, A., Liedtke, D., Knaup, S., Hofrichter, M.A., Müller, T., Dittrich, M., Kong, I.K., Kim, H.G., Haaf, T. and Vona, B.
International Journal of Molecular Sciences 21
(1): 311.
2 January 2020
Genetic spectrum of syndromic and non-syndromic hearing loss in Pakistani families.
Doll, J., Vona, B., Schnapp, L., Rüschendorf, F., Khan, I., Khan, S., Muhammad, N., Alam Khan, S., Nawaz, H., Khan, A., Ahmad, N., Kolb, S.M., Kühlewein, L., Labonne, J.D.J., Layman, L.C., Hofrichter, M.A.H., Röder, T., Dittrich, M., Müller, T., Graves, T.D., Kong, I.K., Nanda, I., Kim, H.G. and Haaf, T.
Genes 11
(11): 1329.
11 November 2020
Polypeptide-corticosteroid conjugates as a topical treatment approach to psoriasis.
Dolz-Pérez, I., Sallam, M.A., Masiá, E., Morelló-Bolumar, D., Pérez Del Caz, M.D., Graff, P., Abdelmonsif, D., Hedtrich, S., Nebot, V.J. and Vicent, M.J.
Journal of Controlled Release 318
: 210-222.
February 2020
Soziodemografische und erwerbsbezogene Merkmale in der NAKO Gesundheitsstudie [Socio-demographic and employment-related factors in the German National Cohort (GNC; NAKO Gesundheitsstudie)].
Dragano, N., Reuter, M., Greiser, K.H., Becher, H., Zeeb, H., Mikolajczyk, R., Kluttig, A., Leitzmann, M., Fischer, B., Jöckel, K.H., Emmel, C., Krause, G., Castell, S., Damms-Machado, A., Obi, N., Schikowski, T., Kuss, O., Hoffmann, W., Schipf, S., Pischon, T., Jaeschke, L., Krist, L., Keil, T., Lieb, W., Holleczek, B., Brenner, H., Wirkner, K., Loeffler, M., Michels, K.B., Franzke, C.W., Peters, A., Linseisen, J., Berger, K., Legath, N., Ahrens, W., Lampert, T. and Schmidt, B.
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 63
(3): 267-278.
March 2020
Association between fatigue and motor exertion in patients with multiple sclerosis - a prospective study.
Drebinger, D., Rasche, L., Kroneberg, D., Althoff, P., Bellmann-Strobl, J., Weygandt, M., Paul, F., Brandt, A.U. and Schmitz-Hübsch, T.
Frontiers in Neurology 11
: 208.
15 April 2020
A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome.
Drivas, T.G., Li, D., Nair, D., Alaimo, J.T., Alders, M., Altmüller, J., Barakat, T.S., Bebin, E.M., Bertsch, N.L., Blackburn, P.R., Blesson, A., Bouman, A.M., Brockmann, K., Brunelle, P., Burmeister, M., Cooper, G.M., Denecke, J., Dieux-Coëslier, A., Dubbs, H., Ferrer, A., Gal, D., Bartik, L.E., Gunderson, L.B., Hasadsri, L., Jain, M., Karimov, C., Keena, B., Klee, E.W., Kloth, K., Lace, B., Macchiaiolo, M., Marcadier, J.L., Milunsky, J.M., Napier, M.P., Ortiz-Gonzalez, X.R., Pichurin, P.N., Pinner, J., Powis, Z., Prasad, C., Radio, F.C., Rasmussen, K.J., Renaud, D.L., Rush, E.T., Saunders, C., Selcen, D., Seman, A.R., Shinde, D.N., Smith, E.D., Smol, T., Snijders Blok, L., Stoler, J.M., Tang, S., Tartaglia, M., Thompson, M.L., van de Kamp, J.M., Wang, J., Weise, D., Weiss, K., Woitschach, R., Wollnik, B., Yan, H., Zackai, E.H., Zampino, G., Campeau, P. and Bhoj, E.
European Journal of Human Genetics 28
(10): 1422-1431.
October 2020
Initiating a new national epilepsy surgery program: experiences gathered in Georgia.
Dugladze, T., Bäuerle, P., Kasradze, S., Lomidze, G., Gzirishvili, N., Tsikarishvili, Vl., Khurtsidze, G., Vida, I., Schmitz, D., Schneider, U.C., Holtkamp, M. and Gloveli, T.
Epilepsy & Behavior 111
: 107259.
October 2020
Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism.
Duscha, A., Gisevius, B., Hirschberg, S., Yissachar, N., Stangl, G.I., Eilers, E., Bader, V., Haase, S., Kaisler, J., David, C., Schneider, R., Troisi, R., Zent, D., Hegelmaier, T., Dokalis, N., Gerstein, S., Del Mare-Roumani, S., Amidror, S., Staszewski, O., Poschmann, G., Stühler, K., Hirche, F., Balogh, A., Kempa, S., Träger, P., Zaiss, M.M., Holm, J.B., Massa, M.G., Nielsen, H.B., Faissner, A., Lukas, C., Gatermann, S.G., Scholz, M., Przuntek, H., Prinz, M., Forslund, S.K., Winklhofer, K.F., Müller, D.N., Linker, R.A., Gold, R. and Haghikia, A.
Cell 180
(6): 1067-1080.
19 March 2020
Brain iron and metabolic abnormalities in C19orf12 mutation carriers: a 7.0 tesla MRI study in mitochondrial membrane protein-associated neurodegeneration.
Dusek, P., Mekle, R., Skowronska, M., Acosta-Cabronero, J., Huelnhagen, T., Robinson, S.D., Schubert, F., Deschauer, M., Els, A., Ittermann, B., Schottmann, G., Madai, V.I., Paul, F., Klopstock, T., Kmiec, T., Niendorf, T., Wuerfel, J. and Schneider, S.A.
Movement Disorders 35
(1): 142-150.
January 2020
Functional classification of TP53 mutations in acute myeloid leukemia.
Dutta, S., Pregartner, G., Rücker, F.G., Heitzer, E., Zebisch, A., Bullinger, L., Berghold, A., Döhner, K. and Sill, H.
Cancers 12
(3): 637.
10 March 2020
Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin.
Dyring-Andersen, B., Løvendorf, M.B., Coscia, F., Santos, A., Møller, L.B.P., Colaço, A.R., Niu, L., Bzorek, M., Doll, S., Andersen, J.L., Clark, R.A., Skov, L., Teunissen, M.B.M. and Mann, M.
Nature Communications 11
(1): 5587.
5 November 2020
Longtime outcome after intraosseous application of autologous mesenchymal stromal cells in pediatric patients and young adults with avascular necrosis after steroid or chemotherapy.
Döring, M., Kluba, T., Cabanillas Stanchi, K.M., Kahle, P., Lenglinger, K., Tsiflikas, I., Treuner, C., Vaegler, M., Mezger, M., Erbacher, A., Schumm, M., Lang, P., Handgretinger, R. and Müller, I.
Stem Cells and Development 29
(13): 811-822.
July 2020
High-dose vitamin D supplementation in multiple sclerosis - results from the randomized EVIDIMS (efficacy of vitamin D supplementation in multiple sclerosis) trial.
Dörr, J., Koduah, P., Wernecke, K.D., Becker, E., Hoffmann, F., Faiss, J., Brockmeier, B., Hoffmann, O., Anvari, K., Wuerfel, J., Piper, S.K., Bellmann-Strobl, J., Brandt, A.U. and Paul, F.
Multiple Sclerosis Journal Experimental Translational and Clinical 6
(1): 2055217320903474.
24 January 2020
Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Edelmann, J., Holzmann, K., Tausch, E., Saunderson, E.A., Jebaraj, B.M.C., Steinbrecher, D., Dolnik, A., Blätte, T.J., Landau, D.A., Saub, J., Estenfelder, S., Ibach, S., Cymbalista, F., Leblond, V., Delmer, A., Bahlo, J., Robrecht, S., Fischer, K., Goede, V., Bullinger, L., Wu, C.J., Mertens, D., Ficz, G., Gribben, J.G., Hallek, M., Döhner, H. and Stilgenbauer, S.
Haematologica 105
(5): 1379-1390.
May 2020
Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
Eede, P., Obst, J., Benke, E., Yvon-Durocher, G., Richard, B.C., Gimber, N., Schmoranzer, J., Böddrich, A., Wanker, E.E., Prokop, S. and Heppner, F.L.
EMBO Reports 21
(3): e48530.
4 March 2020
Wideband self-grounded bow-tie antenna for thermal MR.
Eigentler, T.W., Winter, L., Han, H., Oberacker, E., Kuehne, A., Waiczies, H., Schmitter, S., Boehmert, L., Prinz, C., Trefna, H.D. and Niendorf, T.
NMR in Biomedicine 33
(5): e4274.
May 2020
Is benign MS really benign? What a meaningful classification beyond the EDSS must take into consideration.
Ellenberger, D., Flachenecker, P., Haas, J., Hellwig, K., Paul, F., Stahmann, A., Warnke, C., Zettl, U.K. and Rommer, P.S.
Multiple Sclerosis and Related Disorders 46
: 102485.
November 2020
Neurofibromatosis 1 - mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects.
Elmadany, N., Logiacco, F., Buonfiglioli, A., Haage, V., Wright-Jin, E.C., Schattenberg, A., Papawassiliou, R., Kettenmann, H., Semtner, M. and Gutmann, D.H.
Neurobiology of Disease 144
: 105030.
October 2020
The VGF-derived peptide TLQP21 impairs purinergic control of chemotaxis and phagocytosis in mouse microglia.
Elmadany, N., de Almeida Sassi, F., Wendt, S., Logiacco, F., Visser, J., Haage, V., Perez Hernandez, D., Mertins, P., Hambardzumyan, D., Wolf, S., Kettenmann, H. and Semtner, M.
Journal of Neuroscience 40
(17): 3320-3331.
22 April 2020
Investigation of TEMPO partitioning in different skin models as measured by EPR spectroscopy - insight into the stratum corneum.
Elpelt, A., Ivanov, D., Nováčková, A., Kováčik, A., Sochorová, M., Saeidpour, S., Teutloff, C., Lohan, S.B., Lademann, J., Vávrová, K., Hedtrich, S. and Meinke, M.C.
Journal of Magnetic Resonance 310
: 106637.
January 2020
Is APOE ε4 associated with cognitive performance in early MS?
Engel, S., Graetz, C., Salmen, A., Muthuraman, M., Toenges, G., Ambrosius, B., Bayas, A., Berthele, A., Heesen, C., Klotz, L., Kümpfel, T., Linker, R.A., Meuth, S.G., Paul, F., Stangel, M., Tackenberg, B., Then Bergh, F., Tumani, H., Weber, F., Wildemann, B., Zettl, U.K., Antony, G., Bittner, S., Groppa, S., Hemmer, B., Wiendl, H., Gold, R., Zipp, F., Lill, C.M. and Luessi, F.
Neurology Neuroimmunology & Neuroinflammation 7
(4): e728.
July 2020
Phosphodiesterase 3A and arterial hypertension.
Ercu, M., Markó, L., Schächterle, C., Tsvetkov, D., Cui, Y., Maghsodi, S., Bartolomaeus, T.U.P., Maass, P.G., Zühlke, K., Gregersen, N., Hübner, N., Hodge, R., Mühl, A., Pohl, B., Molé-Illas, R., Geelhaar, A., Walter, S., Napieczynska, H., Schelenz, S., Taube, M., Heuser, A., Anistan, Y.M., Qadri, F., Todiras, M., Plehm, R., Popova, E., Langanki, R., Eichhorst, J., Lehmann, M., Wiesner, B., Russwurm, M., Forslund, S.K., Kamer, I., Müller, D.N., Gollasch, M., Aydin, A., Bähring, S., Bader, M., Luft, F.C. and Klussmann, E.
Circulation 142
(2): 133-149.
14 July 2020
cfNOMe - a single assay for comprehensive epigenetic analyses of cell-free DNA.
Erger, F., Nörling, D., Borchert, D., Leenen, E., Habbig, S., Wiesener, M.S., Bartram, M.P., Wenzel, A., Becker, C., Toliat, M.R., Nürnberg, P., Beck, B.B. and Altmüller, J.
Genome Medicine 12
(1): 54.
24 June 2020
A multi-vendor, multi-center study on reproducibility and comparability of fast strain-encoded cardiovascular magnetic resonance imaging.
Erley, J., Zieschang, V., Lapinskas, T., Demir, A., Wiesemann, S., Haass, M., Osman, N.F., Simonetti, O.P., Liu, Y., Patel, A.R., Mor-Avi, V., Unal, O., Johnson, K.M., Pieske, B., Hansmann, J., Schulz-Menger, J. and Kelle, S.
International Journal of Cardiovascular Imaging 36
(5): 899-911.
May 2020
Angiotensin-converting enzyme inhibitor protects against cisplatin nephrotoxicity by modulating kinin B1 receptor expression and aminopeptidase P activity in mice.
Estrela, G.R., Wasinski, F., Gregnani, M.F., Freitas-Lima, L.C., Arruda, A.C., Morais, R.L., Malheiros, D.M.A.C., Camara, N.O.S., Pesquero, J.B., Bader, M., Barros, C.C. and Araújo, R.C.
Frontiers in Molecular Biosciences 7
: 96.
20 May 2020
Generation of sharp wave-ripple events by disinhibition.
Evangelista, R., Cano, G., Cooper, C., Schmitz, D., Maier, N. and Kempter, R.
Journal of Neuroscience 40
(41): 7811-7836.
7 October 2020
Extracellular myocardial volume in patients with aortic stenosis.
Everett, R.J., Treibel, T.A., Fukui, M., Lee, H., Rigolli, M., Singh, A., Bijsterveld, P., Tastet, L., Musa, T.A., Dobson, L., Chin, C., Captur, G., Om, S.Y., Wiesemann, S., Ferreira, V.M., Piechnik, S.K., Schulz-Menger, J., Schelbert, E.B., Clavel, M.A., Newby, D.E., Myerson, S.G., Pibarot, P., Lee, S., Cavalcante, J.L., Lee, S.P., McCann, G.P., Greenwood, J.P., Moon, J.C. and Dweck, M.R.
Journal of the American College of Cardiology 75
(3): 304-316.
28 January 2020
Binding patterns and functional properties of human antibodies to AQP4 and MOG on murine optic nerve and retina.
Faissner, S., Graz, F., Reinehr, S., Petrikowski, L., Haupeltshofer, S., Ceylan, U., Stute, G., Winklmeier, S., Pache, F., Paul, F., Ruprecht, K., Meinl, E., Dick, H.B., Gold, R., Kleiter, I. and Joachim, S.C.
Journal of Neuroimmunology 342
: 577194.
15 May 2020
Loss of Piccolo function in rats induces cerebellar network dysfunction and Pontocerebellar Hypoplasia type 3-like phenotypes.
Falck, J., Bruns, C., Hoffmann-Conaway, S., Straub, I., Plautz, E.J., Orlando, M., Munawar, H., Rivalan, M., Winter, Y., Izsvák, Z., Schmitz, D., Hamra, F.K., Hallermann, S., Curtis Garner, C. and Ackermann, F.
Journal of Neuroscience 40
(14): 2943-2959.
1 April 2020
Age attenuates the T-type Ca(V) 3.2-RyR axis in vascular smooth muscle.
Fan, G., Kaßmann, M., Cui, Y., Matthaeus, C., Kunz, S., Zhong, C., Zhu, S., Xie, Yu, Tsvetkov, D., Daumke, O., Huang, Yu and Gollasch, M.
Aging Cell 19
(4): e13134.
April 2020
Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C., Urzi, A., Vidal, R., Kunz, S., Ruffault, P.L., Kabuss, L., Hube, I., Gazzerro, E., Birchmeier, C., Spuler, S., Sauer, S. and Gouti, M.
Cell Stem Cell 26
(2): 172-186.
6 February 2020
Stability of neuropsychological test performance in older adults serving as normative controls for a study on postoperative cognitive dysfunction.
Feinkohl, I., Borchers, F., Burkhardt, S., Krampe, H., Kraft, A., Speidel, S., Kant, I.M.J., van Montfort, S.J.T., Aarts, E., Kruppa, J., Slooter, A., Winterer, G., Pischon, T. and Spies, C.
BMC Research Notes 13
(1): 55.
4 February 2020
Plasma leptin, but not adiponectin, is associated with cognitive impairment in older adults.
Feinkohl, I., Janke, J., Slooter, A.J.C., Winterer, G., Spies, C. and Pischon, T.
Psychoneuroendocrinology 120
: 104783.
October 2020
Plasma amyloid concentration in Alzheimer's disease: performance of a high-throughput amyloid assay in distinguishing Alzheimer's disease cases from controls.
Feinkohl, I., Schipke, C.G., Kruppa, J., Menne, F., Winterer, G., Pischon, T. and Peters, O.
Journal of Alzheimer's Disease 74
(4): 1285-1294.
21 April 2020
Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients.
Fendler, A., Bauer, D., Busch, J., Jung, K., Wulf-Goldenberg, A., Kunz, S., Song, K., Myszczyszyn, A., Elezkurtaj, S., Erguen, B., Jung, S., Chen, W. and Birchmeier, W.
Nature Communications 11
(1): 929.
17 February 2020
Stimulation of mGluR1/5 improves defective internalization of AMPA receptors in NPC1 mutant mouse.
Feng, X., Yang, F., Rabenstein, M., Wang, Z., Frech, M.J., Wree, A., Bräuer, A.U., Witt, M., Gläser, A., Hermann, A., Rolfs, A. and Luo, J.
Cerebral Cortex 30
(3): 1465-1480.
March 2020
FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth.
Ferdous, A., Wang, Z.V., Luo, Y., Li, D.L., Luo, X., Schiattarella, G.G., Altamirano, F., May, H.I., Battiprolu, P.K., Nguyen, A., Rothermel, B.A., Lavandero, S., Gillette, T.G. and Hill, J.A.
Nature Communications 11
(1): 2551.
21 May 2020
Autocalibrated cardiac tissue phase mapping with multiband imaging and k-t acceleration.
Ferrazzi, G., Bassenge, J.P., Mayer, J., Ruh, A., Roujol, S., Ittermann, B., Schaeffter, T., Cordero-Grande, L. and Schmitter, S.
Magnetic Resonance in Medicine 84
(5): 2429-2441.
November 2020
Age-of-onset information helps identify 76 genetic variants associated with allergic disease.
Ferreira, M.A.R., Vonk, J.M., Baurecht, H., Marenholz, I., Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, Vi., Lu, Y., Grosche, S., Rüschendorf, F., Granell, R., Brumpton, B.M., Fritsche, L.G., Bhatta, L., Gabrielsen, M.E., Nielsen, J.B., Zhou, W., Hveem, K., Langhammer, A., Holmen, O.L., Løset, M., Abecasis, G.R., Willer, C.J., Emami, N.C., Cavazos, T.B., Witte, J.S., Szwajda, A., Hinds, D.A., Hübner, N., Weidinger, S., Magnusson, P.K., Jorgenson, E., Karlsson, R., Paternoster, L., Boomsma, D.I., Almqvist, C., Lee, Y.A. and Koppelman, G.H.
PLoS Genetics 16
(6): e1008725.
30 June 2020
Inference of chromosome 3D structures from GAM data by a physics computational approach.
Fiorillo, L., Bianco, S., Chiariello, A.M., Barbieri, M., Esposito, A., Annunziatella, C., Conte, M., Corrado, A., Prisco, A., Pombo, A. and Nicodemi, M.
Methods 181-182
: 70-79.
1 October 2020
Anthropometrische Messungen in der NAKO Gesundheitsstudie - mehr als nur Größe und Gewicht [Anthropometric measures in the German National Cohort - more than weight and height].
Fischer, B., Sedlmeier, A.M., Hartwig, S., Schlett, C.L., Ahrens, W., Bamberg, F., Baurecht, H., Becher, H., Berger, K., Binder, H., Bohn, B., Carr, P.R., Castell, S., Franzke, C.W., Fricke, J., Gastell, S., Greiser, K.H., Günther, K., Jaeschke, L., Kaaks, R., Kemmling, Y., Krist, L., Kuß, O., Legath, N., Lieb, W., Linseisen, J., Löffler, M., Michels, K.B., Mikolajczyk, R., Niedermaier, T., Norman, K., Obi, N., Peters, A., Pischon, T., Schikowski, T., Schipf, S., Schmidt, B., Schulze, M.B., Stang, A., Stojicic, J., Tiller, D., Völzke, H., Waniek, S. and Leitzmann, M.F.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(3): 290-300.
March 2020
Induced pluripotent stem cell-based disease modeling identifies ligand-induced decay of megalin as a cause of Donnai-Barrow syndrome.
Flemming, J., Marczenke, M., Rudolph, I.M., Nielsen, R., Storm, T., Ilsoe Christensen, E., Diecke, S., Emma, F. and Willnow, T.E.
Kidney International 98
(1): 159-167.
July 2020
An exploratory investigation of brain collateral circulation plasticity after cerebral ischemia in two experimental C57BL/6 mouse models.
Foddis, M., Winek, K., Bentele, K., Mueller, S., Blumenau, S., Reichhart N, N., Crespo-Garcia, S., Harnett, D., Ivanov, A., Meisel, A., Joussen, A., Strauss, O., Beule, D., Dirnagl, U. and Sassi, C.
Journal of Cerebral Blood Flow and Metabolism 40
(2): 276-287.
1 February 2020
CD8-specific designed ankyrin repeat proteins improve selective gene delivery into human and primate T lymphocytes.
Frank, A.M., Weidner, T., Brynza, J., Uckert, W., Buchholz, C.J. and Hartmann, J.
Human Gene Therapy 31
(11-12): 679-691.
June 2020
Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency.
Freitag, N., Tirado-Gonzalez, I., Barrientos, G., Powell, K.L., Boehm-Sturm, P., Koch, S.P., Hecher, K., Staff, A.C., Arck, P.C., Diemert, A. and Blois, S.M.
Cell Death & Disease 11
(7): 560.
23 July 2020
The Chimera-type galectin-3 is a positive modulator of trophoblast functions with dysregulated expression in gestational diabetes mellitus.
Freitag, N., Tirado-González, I., Barrientos, G., Cohen, M., Daher, S., Goldman-Wohl, D., Mincheva-Nilsson, L., John, C., Jeschke, U. and Blois, S.M.
American Journal of Reproductive Immunology 84
(6): e13311.
December 2020
Progression-dependent altered metabolism in osteosarcoma resulting in different nutrient source dependencies.
Fritsche-Guenther, R., Gloaguen, Y., Kirchner, M., Mertins, P., Tunn, P.U. and Kirwan, J.A.
Cancers 12
(6): 1371.
27 May 2020
A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation.
Gaertner, B., van Heesch, S., Schneider-Lunitz, V., Schulz, J.F., Witte, F., Blachut, S., Nguyen, S., Wong, R., Matta, I., Hübner, N. and Sander, M.
eLife 9
: e58659.
3 August 2020
A conserved noncoding locus regulates random monoallelic Xist expression across a topological boundary.
Galupa, R., Nora, E.P., Worsley-Hunt, R., Picard, C., Gard, C., van Bemmel, J.G., Servant, N., Zhan, Y., El Marjou, F., Johanneau, C., Diabangouaya, P., Le Saux, A., Lameiras, S., Pipoli da Fonseca, J., Loos, F., Gribnau, J., Baulande, S., Ohler, U., Giorgetti, L. and Heard, E.
Molecular Cell 77
(2): 352-367.
16 January 2020
Genetic determinants of the humoral immune response in MS.
Gasperi, C., Andlauer, T.F.M., Keating, A., Knier, B., Klein, A., Pernpeintner, V., Lichtner, P., Gold, R., Zipp, F., Then Bergh, F., Stangel, M., Tumani, H., Wildemann, B., Wiendl, H., Bayas, A., Kümpfel, T., Zettl, U.K., Linker, R.A., Ziemann, U., Knop, M., Warnke, C., Friese, M.A., Paul, F., Tackenberg, B., Berthele, A. and Hemmer, B.
Neurology Neuroimmunology & Neuroinflammation 7
(5): e827.
September 2020
Prognostic value of stress CMR perfusion imaging in patients with reduced left ventricular function.
Ge, Y., Antiochos, P., Steel, K., Bingham, S., Abdullah, S., Chen, Y.Y., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Shanbhag, S.M., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 13
(10): 2132-2145.
October 2020
Cost-effectiveness analysis of stress cardiovascular magnetic resonance imaging for stable chest pain syndromes.
Ge, Y., Pandya, A., Steel, K., Bingham, S., Jerosch-Herold, M., Chen, Y.Y., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Hachamovitch, R., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 13
(7): 1505-1517.
July 2020
Lysine 4 of histone H3.3 is required for embryonic stem cell differentiation, histone enrichment at regulatory regions and transcription accuracy.
Gehre, M., Bunina, D., Sidoli, S., Lübke, M.J., Diaz, N., Trovato, M., Garcia, B.A., Zaugg, J.B. and Noh, K.M.
Nature Genetics 52
(3): 273-282.
March 2020
Long-lived tumor-associated macrophages in glioma.
Georgieva, P.B., Mathivet, T., Alt, S., Giese, W., Riva, M., Balcer, M. and Gerhardt, H.
Neuro-Oncology Advances 2
(1): vdaa127.
9 November 2020
CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex.
Gerbracht, J.V., Boehm, V., Britto-Borges, T., Kallabis, S., Wiederstein, J.L., Ciriello, S., Aschemeier, D.U., Krüger, M., Frese, C.K., Altmüller, J., Dieterich, C. and Gehring, N.H.
Nucleic Acids Research 48
(15): 8626-8644.
4 September 2020
pH-dependent protonation of surface carboxylate groups in PsbO enables local buffering and triggers structural changes.
Gerland, L. M., Friedrich, D., Hopf, L., Donovan, E., Wallmann, A., Erdmann, N., Diehl, A., Bommer, M., Buzar, K., Ibrahim, M., Schmieder, P., Dobbek, H., Zouni, A., Bondar, A.-N., Dau, H. and Oschkinat, H.
ChemBioChem 21
(11): 1597-1604.
2 June 2020
Deep neural networks for interpreting RNA-binding protein target preferences.
Ghanbari, M. and Ohler, U.
Genome Research 30
(2): 214-226.
February 2020
Prostaglandin E(2) in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8(+) T cells.
Gierlich, P., Lex, V., Technau, A., Keupp, A., Morper, L., Glunz, A., Sennholz, H., Rachor, J., Sauer, S., Marcu, A., Grigoleit, G.U., Wölfl, M., Schlegel, P.G. and Eyrich, M.
Cancer Immunology Immunotherapy 69
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June 2020
Cxcl10(+) monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation.
Giladi, A., Wagner, L.K., Li, H., Dörr, D., Medaglia, C., Paul, F., Shemer, A., Jung, S., Yona, S., Mack, M., Leutz, A., Amit, I. and Mildner, A.
Nature Immunology 21
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May 2020
GPSeq reveals the radial organization of chromatin in the cell nucleus.
Girelli, G., Custodio, J., Kallas, T., Agostini, F., Wernersson, E., Spanjaard, B., Mota, A., Kolbeinsdottir, S., Gelali, E., Crosetto, N. and Bienko, M.
Nature Biotechnology 38
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October 2020
Lymphoma angiogenesis is orchestrated by noncanonical signaling pathways.
Gloger, M., Menzel, L., Grau, M., Vion, A.C., Anagnostopoulos, I., Zapukhlyak, M., Gerlach, K., Kammertöns, T., Hehlgans, T., Zschummel, M., Lenz, G., Gerhardt, H., Höpken, U.E. and Rehm, A.
Cancer Research 80
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March 2020
Effects of hemodialysis on blood fatty acids.
Gollasch, B., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 8
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January 2020
Effects of hemodialysis on plasma oxylipins.
Gollasch, B., Wu, G., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 8
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June 2020
Hemodialysis and erythrocyte epoxy fatty acids.
Gollasch, B., Wu, G., Liu, T., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 8
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October 2020
Type I phosphatidylinositol-4-phosphate 5-kinase α and γ play a key role in targeting HIV-1 Pr55(Gag) to the plasma membrane.
Gonzales, B., de Rocquigny, H., Beziau, A., Durand, S., Burlaud-Gaillard, J., Lefebvre, A., Krull, S., Emond, P., Brand, D. and Piver, E.
Journal of Virology 94
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1 July 2020
Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage.
Goulielmaki, E., Ioannidou, A., Tsekrekou, M., Stratigi, K., Poutakidou, I.K., Gkirtzimanaki, K., Aivaliotis, M., Evangelou, K., Topalis, P., Altmüller, J., Gorgoulis, V.G., Chatzinikolaou, G. and Garinis, G.A.
Nature Communications 11
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2 January 2020
Vampires and nurses are rated differently by younger and older adults - age-comparative norms of imageability and emotionality for about 2500 German nouns.
Grandy, T.H., Lindenberger, U. and Schmiedek, F.
Behavior Research Methods 52
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June 2020
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.
Greiner, J., Götz, M., Hofmann, S., Schrezenmeier, H., Wiesneth, M., Bullinger, L., Döhner, H. and Schneider, V.
Cancer Immunology Immunotherapy 69
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April 2020
Ensuring center quality, proper patient selection and fair access to chimeric antigen receptor T-cell therapy: position statement of the Austrian CAR-T Cell Network.
Greinix, H.T., Attarbaschi, A., Girschikofsky, M., Greil, R., Holter, W., Neumeister, P., Peters, C., Petzer, A., Rudzki, J., Schlenke, P., Schmitt, C.A., Schwinger, W., Wolf, D., Worel, N. and Jaeger, U.
memo: Magazine of European Medical Oncology 13
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March 2020
Early antihypertensive treatment and ischemia-induced acute kidney injury.
Greite, R., Derlin, K., Hensen, B., Thorenz, A., Rong, S., Chen, R., Hellms, S., Jang, M.S., Bräsen, J.H., Meier, M., Willenberg, I., Immenschuh, S., Haller, H., Luft, F.C., Panigrahy, D., Hwang, S.H., Hammock, B.D., Schebb, N.H. and Gueler, F.
American Journal of Physiology Renal Physiology 319
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October 2020
The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat, J., Heuberger, J., Vidal, R., Goveas, N., Kosel, F., Berenguer-Llergo, A., Kranz, A., Wulf-Goldenberg, A., Behrens, D., Melcher, B., Sauer, S., Vieth, M., Batlle, E., Stewart, A. and Birchmeier, W.
Nature Communications 11
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21 December 2020
Mechanism of virus attenuation by codon pair deoptimization.
Groenke, N., Trimpert, J., Merz, S., Conradie, A.M., Wyler, E., Zhang, H., Hazapis, O.G., Rausch, S., Landthaler, M., Osterrieder, N. and Kunec, D.
Cell Reports 31
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28 April 2020
Epigenetic regulator function through mouse gastrulation.
Grosswendt, S., Kretzmer, H., Smith, Z.D., Kumar, A.S., Hetzel, S., Wittler, L., Klages, S., Timmermann, B., Mukherji, S. and Meissner, A.
Nature 584
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6 August 2020
The needle in the haystack - searching for genetic and epigenetic differences in monozygotic twins discordant for Tetralogy of Fallot.
Grunert, M., Appelt, S., Grossfeld, P. and Sperling, S.R.
Journal of Cardiovascular Development and Disease 7
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2 December 2020
Induced pluripotent stem cells of patients with Tetralogy of Fallot reveal transcriptional alterations in cardiomyocyte differentiation.
Grunert, M., Appelt, S., Schönhals, S., Mika, K., Cui, H., Cooper, A., Cyganek, L., Guan, K. and Sperling, S.R.
Scientific Reports 10
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2 July 2020
Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Grunwald, S., Hopf, L.V.M., Bock-Bierbaum, T., Lally, C.C.M., Spahn, C.M.T. and Daumke, O.
Nature Communications 11
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2 November 2020
Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
Scientific Reports 10
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7 February 2020
Establishing a sensitive fluorescence-based quantification method for cyclic nucleotides.
Gruteser, N., Kohlhas, V., Balfanz, S., Franzen, A., Günther, A., Offenhäusser, A., Müller, F., Nikolaev, V., Lohse, M.J. and Baumann, A.
BMC Biotechnology 20
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27 August 2020
Inefficient CAR-proximal signaling blunts antigen sensitivity.
Gudipati, V., Rydzek, J., Doel-Perez, I., Gonçalves, V.D.R., Scharf, L., Königsberger, S., Lobner, E., Kunert, R., Einsele, H., Stockinger, H., Hudecek, M. and Huppa, J.B.
Nature Immunology 21
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August 2020
Saffron crudes and compounds restrict MACC1-dependent cell proliferation and migration of colorectal cancer cells.
Güllü, N., Kobelt, D., Brim, H., Rahman, S., Timm, L., Smith, J., Soleimani, A., Di Marco, S., Bisti, S., Ashktorab, H. and Stein, U.
Cells 9
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3 August 2020
RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Haase, N., Foster, D.J., Cunningham, M.W., Bercher, J., Nguyen, T., Shulga-Morskaya, S., Milstein, S., Shaikh, S., Rollins, J., Golic, M., Herse, F., Kräker, K., Bendix, I., Serdar, M., Napieczynska, H., Heuser, A., Gellhaus, A., Thiele, K., Wallukat, G., Müller, D.N., LaMarca, B. and Dechend, R.
Journal of Clinical Investigation 130
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1 June 2020
Long-term data on two sisters with C3GN due to an identical, homozygous CFH mutation and autoantibodies.
Hackl, A., Erger, F., Skerka, C., Wenzel, A., Tschernoster, N., Ehren, R., Burgmaier, K., Riehmer, V., Licht, C., Kirschfink, M., Weber, L.T., Altmueller, J., Zipfel, P.F. and Habbig, S.
Clinical Nephrology 94
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October 2020
The effect of ageing and cerebral serotonin deficit on the activity of cytochrome P450 2D (CYP2D) in the brain and liver of male rats.
Haduch, A., Pukło, R., Alenina, N., Nikiforuk, A., Popik, P., Bader, M. and Daniel, W.A.
Neurochemistry International 141
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December 2020
Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains.
Haenig, C., Atias, N., Taylor, A.K., Mazza, A., Schaefer, M.H., Russ, J., Riechers, S.P., Jain, S., Coughlin, M., Fontaine, J.F., Freibaum, B.D., Brusendorf, L., Zenkner, M., Porras, P., Stroedicke, M., Schnoegl, S., Arnsburg, K., Boeddrich, A., Pigazzini, L., Heutink, P., Taylor, J.P., Kirstein, J., Andrade-Navarro, M.A., Sharan, R. and Wanker, E.E.
Cell Reports 32
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18 August 2020
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M., Pablo-Tortola, C., Todiras, M., Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M., Jarosch, E., Sommer, T., Bröker, B.M., Felix, S.B., Scheidereit, C., Weber-Carstens, S., Butter, C., Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 11
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February 2020
Design, implementation, evaluation and application of a 32-channel radio frequency signal generator for thermal magnetic resonance based anti-cancer treatment.
Han, H., Eigentler, T.W., Wang, S., Kretov, E., Winter, L., Hoffmann, W., Grass, E. and Niendorf, T.
Cancers 12
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28 June 2020
Intronic CRISPR repair in a preclinical model of Noonan syndrome-associated cardiomyopathy.
Hanses, U., Kleinsorge, M., Roos, L., Yigit, G., Li, Y., Barbarics, B., El-Battrawy, I., Lan, H., Tiburcy, M., Hindmarsh, R., Lenz, C., Salinas, G., Diecke, S., Müller, C., Adham, I., Altmüller, J., Nürnberg, P., Paul, T., Zimmermann, W.H., Hasenfuss, G., Wollnik, B. and Cyganek, L.
Circulation 142
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15 September 2020
Selbst berichtete Infektionen in der NAKO Gesundheitsstudie - Einordnung in die gegenwärtige Forschungslandschaft [Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape].
Hassenstein, M.J., Aarabi, G., Ahnert, P., Becher, H., Franzke, C.-W., Fricke, J., Krause, G., Glöckner, S., Gottschick, C., Karch, A., Kemmling, Y., Kerrinnes, T., Lange, B., Mikolajczyk, R., Nieters, A., Ott, J.J., Ahrens, W., Berger, K., Meinke-Franze, C., Gastell, S., Günther, K., Greiser, K.H., Holleczek, B., Horn, J., Jaeschke, L., Jagodzinski, A., Jansen, L., Jochem, C., Jöckel, K.H., Kaaks, R., Krist, L., Kuß, O., Langer, S., Legath, N., Leitzmann, M., Lieb, W., Loeffler, M., Mangold, N., Michels, K.B., Meisinger, C., Obi, N., Pischon, T., Schikowski, T., Schipf, S., Schulze, M.B., Stang, A., Waniek, S., Wirkner, K., Willich, S.N. and Castell, S.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
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April 2020
High-risk additional chromosomal abnormalities at low blast counts herald death by CML.
Hehlmann, R., Voskanyan, A., Lauseker, M., Pfirrmann, M., Kalmanti, L., Rinaldetti, S., Kohlbrenner, K., Haferlach, C., Schlegelberger, B., Fabarius, A., Seifarth, W., Spieß, B., Wuchter, P., Krause, S., Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Burchert, A., Brümmendorf, T.H., Hasford, J., Hochhaus, A., Saußele, S. and Baccarani, M.
Leukemia 34
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August 2020
Transdiagnostic hippocampal damage patterns in neuroimmunological disorders.
Heine, J., Prüß, H., Scheel, M., Brandt, A.U., Gold, S.M., Bartsch, T., Paul, F. and Finke, C.
NeuroImage: Clinical 28
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2020
Radiological, chemical, and pharmacological cholinergic system parameters and neurocognitive disorders in older presurgical adults.
Heinrich, M., Müller, A., Lammers-Lietz, F., Borchers, F., Mörgeli, R., Kruppa, J., Zacharias, N., Winterer, G., Slooter, A.J.C. and Spies, C.D.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences 76
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June 2020
Addiction Research Consortium: losing and regaining control over drug intake (ReCoDe) - from trajectories to mechanisms and interventions.
Heinz, A., Kiefer, F., Smolka, M.N., Endrass, T., Beste, C., Beck, A., Liu, S., Genauck, A., Romund, L., Banaschewski, T., Bermpohl, F., Deserno, L., Dolan, R.J., Durstewitz, D., Ebner-Priemer, U., Flor, H., Hansson, A.C., Heim, C., Hermann, D., Kiebel, S., Kirsch, P., Kirschbaum, C., Koppe, G., Marxen, M., Meyer-Lindenberg, A., Nagel, W.E., Noori, H.R., Pilhatsch, M., Priller, J., Rietschel, M., Romanczuk-Seiferth, N., Schlagenhauf, F., Sommer, W.H., Stallkamp, J., Ströhle, A., Stock, A.K., Winterer, G., Winter, C., Walter, H., Witt, S., Vollstädt-Klein, S., Rapp, M.A., Tost, H. and Spanagel, R.
Addiction Biology 25
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March 2020
Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study.
Heitmann, H., Haller, B., Tiemann, L., Mühlau, M., Berthele, A., Tölle, T.R., Salmen, A., Ambrosius, B., Bayas, A., Asseyer, S., Hartung, H.P., Heesen, C., Stangel, M., Wildemann, B., Haars, S., Groppa, S., Luessi, F., Kümpfel, T., Nischwitz, S., Meuth, S.G., Klotz, L., Linker, R.A., Zettl, U.K., Ziemann, U., Tumani, H., Tackenberg, B., Zipp, F., Wiendl, H., Gold, R., Hemmer, B. and Ploner, M.
Pain 161
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April 2020
Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state.
Helker, C.S.M., Eberlein, J., Wilhelm, K., Sugino, T., Malchow, J., Schuermann, A., Baumeister, S., Kwon, H.B., Maischein, H.M., Potente, M., Herzog, W. and Stainier, D.Y.R.
eLife 9
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21 September 2020
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Helmsauer, K., Valieva, M.E., Ali, S., Chamorro Gonzalez, R., Schöpflin, R., Röefzaad, C., Bei, Y., Dorado Garcia, H., Rodriguez-Fos, E., Puiggròs, M., Kasack, K., Haase, K., Keskeny, C., Chen, C.Y., Kuschel, L.P., Euskirchen, P., Heinrich, V., Robson, M.I., Rosswog, C., Toedling, J., Szymansky, A., Hertwig, F., Fischer, M., Torrents, D., Eggert, A., Schulte, J.H., Mundlos, S., Henssen, A.G. and Koche, R.P.
Nature Communications 11
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16 November 2020
CXCR4-targeted PET imaging of central nervous system B-cell lymphoma.
Herhaus, P., Lipkova, J., Lammer, F., Yakushev, I., Vag, T., Slotta-Huspenina, J., Habringer, S., Lapa, C., Pukrop, T., Hellwig, D., Wiestler, B., Buck, A.K., Deckert, M., Wester, H.J., Bassermann, F., Schwaiger, M., Weber, W.A., Menze, B. and Keller, U.
Journal of Nuclear Medicine 61
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1 December 2020
α2A-adrenoceptors modulate renal sympathetic neurotransmission and protect against hypertensive kidney disease.
Hering, L., Rahman, M., Hoch, H., Markó, L., Yang, G., Reil, A., Yakoub, M., Gupta, V., Potthoff, S.A., Vonend, O., Ralph, D.L., Gurley, S.B., McDonough, A.A., Rump, L.C. and Stegbauer, J.
Journal of the American Society of Nephrology 31
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April 2020
Viral cGAMP nuclease reveals the essential role of DNA sensing in protection against acute lethal virus infection.
Hernáez, B., Alonso, G., Georgana, I., El-Jesr, M., Martín, R., Shair, K.H.Y., Fischer, C., Sauer, S., Maluquer de Motes, C. and Alcamí, A.
Science Advances 6
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18 September 2020
Final results of a phase I/II trial of the combination Bendamustine and Rituximab with Temsirolimus (BeRT) in relapsed mantle cell lymphoma and follicular lymphoma.
Hess, G., Wagner, K., Keller, U., La Rosee, P., Atta, J., Hübel, K., Lerchenmueller, C., Schoendube, D., Witzens-Harig, M., Ruckes, C., Medler, C., van Oordt, C., Klapper, W., Theobald, M. and Dreyling, M.
HemaSphere 4
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June 2020
Association for European Paediatric and Congenital Cardiology recommendations for basic training in paediatric and congenital cardiology 2020.
Heying, R., Albert, D.C., Voges, I., Sendzikaite, S., Sarquella-Brugada, G., Pluchinotta, F., Brzezinska-Rajszys, G., Stein, J.I. and Milanesi, O.
Cardiology in the Young 30
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November 2020
BRAVE-NET: fully automated arterial brain vessel segmentation in patients with cerebrovascular disease.
Hilbert, A., Madai, V.I., Akay, E.M., Aydin, O.U., Behland, J., Sobesky, J., Galinovic, I., Khalil, A.A., Taha, A.A.A., Wuerfel, J., Dusek, P., Niendorf, T., Fiebach, J.B., Frey, D. and Livne, M.
Frontiers in Artificial Intelligence 3
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25 September 2020
Comprehensive analysis of translation from overexpressed circular RNAs reveals pervasive translation from linear transcripts.
Ho-Xuan, H., Glažar, P., Latini, C., Heizler, K., Haase, J., Hett, R., Anders, M., Weichmann, F., Bruckmann, A., Van den Berg, D., Hüttelmaier, S., Rajewsky, N., Hackl, C. and Meister, G.
Nucleic Acids Research 48
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9 October 2020
Comparative efficacy of targeted therapies in patients with non-small cell lung cancer: a network meta-analysis of clinical trials.
Hoang, T., Myung, S.K., Pham, T.T., Kim, J. and Ju, W.
Journal of Clinical Medicine 9
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April 2020
Efficacy of crizotinib, ceritinib, and alectinib in ALK-positive non-small cell lung cancer treatment: a meta-analysis of clinical trials.
Hoang, T., Myung, S.K., Pham, T.T. and Park, B.
Cancers 12
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25 February 2020
FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease.
Hoffmann, S., Pentakota, S., Mund, A., Haahr, P., Coscia, F., Gallo, M., Mann, M., Taylor, N.M. and Mailand, N.
EMBO Reports 21
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5 October 2020
MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma.
Hohmann, T., Hohmann, U., Kolbe, M.R., Dahlmann, M., Kobelt, D., Stein, U. and Dehghani, F.
Cell Communication and Signaling 18
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5 June 2020
Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling.
Hollenhorst, M.I., Jurastow, I., Nandigama, R., Appenzeller, S., Li, L., Vogel, J., Wiederhold, S., Althaus, M., Empting, M., Altmüller, J., Hirsch, A.K.H., Flockerzi, V., Canning, B.J., Saliba, A.E. and Krasteva-Christ, G.
FASEB Journal 34
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January 2020
Design und Qualitätskontrolle der zahnmedizinischen Untersuchung in der NAKO Gesundheitsstudie [Design and quality control of the oral health status examination in the German National Cohort (GNC)].
Holtfreter, B., Samietz, S., Hertrampf, K., Aarabi, G., Hagenfeld, D., Kim, T.S., Kocher, T., Koos, B., Schmitter, M., Ahrens, W., Alwers, E., Becher, H., Berger, K., Brenner, H., Damms-Machado, A., Ebert, N., Fischer, B., Franzke, C.W., Frölich, S., Greiser, H., Gies, A., Günther, K., Hassan, L., Hoffmann, W., Jaeschke, L., Keil, T., Kemmling, Y., Krause, G., Krist, L., Legath, N., Lieb, W., Leitzmann, M., Linseisen, J., Loeffler, M., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Obi, N., Peters, A., Pischon, T., Schipf, S., Schmidt, B., Völzke, H., Waniek, S., Wigmann, C., Wirkner, K., Schmidt, C.O., Kühnisch, J. and Rupf, S.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(4): 426-438.
April 2020
Digestiflow: from BCL to FASTQ with ease.
Holtgrewe, M., Messerschmidt, C., Nieminen, M. and Beule, D.
Bioinformatics 36
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15 March 2020
VarFish: comprehensive DNA variant analysis for diagnostics and research.
Holtgrewe, M., Stolpe, O., Nieminen, M., Mundlos, S., Knaus, A., Kornak, U., Seelow, D., Segebrecht, L., Spielmann, M., Fischer-Zirnsak, B., Boschann, F., Scholl, U., Ehmke, N. and Beule, D.
Nucleic Acids Research 48
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2 July 2020
Ligand-specific allosteric coupling controls G-protein-coupled receptor signaling.
Holze, J., Bermudez, M., Pfeil, E.M., Kauk, M., Bödefeld, T., Irmen, M., Matera, C., Dallanoce, C., De Amici, M., Holzgrabe, U., König, G.M., Tränkle, C., Wolber, G., Schrage, R., Mohr, K., Hoffmann, C., Kostenis, E. and Bock, A.
ACS Pharmacology & Translational Science 3
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9 October 2020
Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly.
Hong, M., Christ, A., Christa, A., Willnow, T.E. and Krauss, R.S.
eLife 9
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2 September 2020
Authentication of primary murine cell lines by a microfluidics-based lab-on-chip system.
Hong, Y., Singh, N., Bamopoulos, S., Gjerga, E., Schmalbrock, L.K., Balabanian, K., Schick, M., Keller, U. and Wirth, M.
Biomedicines 8
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9 December 2020
A multi-modal virtual reality treadmill intervention for enhancing mobility and cognitive function in people with multiple sclerosis: protocol for a randomized controlled trial.
Hsieh, K.L., Mirelman, A., Shema-Shiratzky, S., Galperin, I., Regev, K., Shen, S., Schmitz-Hübsch, T., Karni, A., Paul, F., Devos, H., Sosnoff, J.J. and Hausdorff, J.M.
Contemporary Clinical Trials 97
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October 2020
Down-regulation of Aquaporin-1 mediates a microglial phenotype switch affecting glioma growth.
Hu, F., Huang, Y., Semtner, M., Zhao, K., Tan, Z., Dzaye, O., Kettenmann, H., Shu, K. and Lei, T.
Experimental Cell Research 396
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15 November 2020
FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells.
Hu, J.L., Liang, H., Zhang, H., Yang, M.Z., Sun, W., Zhang, P., Luo, L., Feng, J.X., Bai, H., Liu, F., Zhang, T., Yang, J.Y., Gao, Q., Long, Y., Ma, X.Y., Chen, Y., Zhong, Q., Yu, B., Liao, S., Wang, Y., Zhao, Y., Zeng, M.S., Cao, N., Wang, J., Chen, W., Yang, H.T. and Gao, S.
Nucleic Acids Research 48
(5): 2733-2748.
18 March 2020
Integrated proteomic and glycoproteomic characterization of human high-grade serous ovarian carcinoma.
Hu, Y., Pan, J., Shah, P., Ao, M., Thomas, S.N., Liu, Y., Chen, L., Schnaubelt, M., Clark, D.J., Rodriguez, H., Boja, E.S., Hiltke, T., Kinsinger, C.R., Rodland, K.D., Li, Q.K., Qian, J., Zhang, Z., Chan, D.W. and Zhang, H.
Cell Reports 33
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20 October 2020
MEK inhibitor trametinib attenuates neuroinflammation and cognitive deficits following traumatic brain injury in mice.
Huang, Y., Li, Q., Tian, H., Yao, X., Bakina, O., Zhang, H., Lei, T. and Hu, F.
American Journal of Translational Research 12
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15 October 2020
Synergistic toll-like receptor 3/9 signaling affects properties and impairs glioma-promoting activity of microglia.
Huang, Y., Zhang, Q., Lubas, M., Yuan, Y., Yalcin, F., Efe, I.E., Xia, P., Motta, E., Buonfiglioli, A., Lehnardt, S., Dzaye, O., Flueh, C., Synowitz, M., Hu, Feng and Kettenmann, H.
Journal of Neuroscience 40
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12 August 2020
Local and central evaluation of HER2 positivity and clinical outcome in advanced gastric and gastroesophageal cancer: results from the AGMT GASTRIC-5 Registry.
Huemer, F., Weiss, L., Regitnig, P., Winder, T., Hartmann, B., Thaler, J., Piringer, G., Schmitt, C.A., Eisterer, W., Gänzer, H., Wüstner, Al., Andel, J., Jagdt, B., Ulmer, H., Greil, R. and Wöll, E.
Journal of Clinical Medicine 9
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29 March 2020
The International Virus Bioinformatics Meeting 2020.
Hufsky, F., Beerenwinkel, N., Meyer, I.M., Roux, S., Cook, G.M., Kinsella, C.M., Lamkiewicz, K., Marquet, M., Nieuwenhuijse, D.F., Olendraite, I., Paraskevopoulou, S., Young, F., Dijkman, R., Ibrahim, B., Kelly, J., Le Mercier, P., Marz, M., Ramette, A. and Thiel, V.
Viruses 12
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6 December 2020
Emotional experience in patients with clinically isolated syndrome and early multiple sclerosis.
Hälbig, T.D., Wüstenberg, T., Giess, R.M., Kunte, H., Bellmann-Strobl, J., Ruprecht, K. and Paul, F.
European Journal of Neurology 27
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August 2020
Rescue of oxytocin response and social behaviour in a mouse model of autism.
Hörnberg, H., Pérez-Garci, E., Schreiner, D., Hatstatt-Burklé, L., Magara, F., Baudouin, S., Matter, A., Nacro, K., Pecho-Vrieseling, E. and Scheiffele, P.
Nature 584
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13 August 2020
Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury.
Ifuku, M., Hinkelmann, L., Kuhrt, L.D., Efe, I.E., Kumbol, V., Buonfiglioli, A., Krüger, C., Jordan, P., Fulde, M., Noda, M., Kettenmann, H. and Lehnardt, S.
Acta Neuropathologica Communications 8
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10 September 2020
Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.
Ihantola, T., Di Bucchianico, S., Happo, M., Ihalainen, M., Uski, O., Bauer, S., Kuuspalo, K., Sippula, O., Tissari, J., Oeder, S., Hartikainen, A., Rönkkö, T.J., Martikainen, M.V., Huttunen, K., Vartiainen, P., Suhonen, H., Kortelainen, M., Lamberg, H., Leskinen, A., Sklorz, M., Michalke, B., Dilger, M., Weiss, C., Dittmar, G., Beckers, J., Irmler, M., Buters, J., Candeias, J., Czech, H., Yli-Pirilä, P., Abbaszade, G., Jakobi, G., Orasche, J., Schnelle-Kreis, J., Kanashova, T., Karg, E., Streibel, T., Passig, J., Hakkarainen, H., Jokiniemi, J., Zimmermann, R., Hirvonen, M.R. and Jalava, P.I.
Particle and Fibre Toxicology 17
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15 June 2020
Investigation of visual system involvement in spinocerebellar ataxia type 14.
Ihl, T., Kadas, E.M., Oberwahrenbrock, T., Endres, M., Klockgether, T., Schroeter, J., Brandt, A.U., Paul, F., Minnerop, M., Doss, S., Schmitz-Hübsch, T. and Zimmermann, H.G.
Cerebellum 19
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August 2020
Impact of chronic kidney disease on platelet aggregation in patients with acute coronary syndrome.
Ilardi, F., Gargiulo, G., Paolillo, R., Ferrone, M., Cimino, S., Giugliano, G., Schiattarella, G.G., Verde, N., Stabile, E., Perrino, C., Cirillo, P., Coscioni, E., Morisco, C. and Esposito, G.
Journal of Cardiovascular Medicine 21
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September 2020
Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease.
Izarzugaza, J.M.G., Ellesøe, S.G., Doganli, C., Ehlers, N.S., Dalgaard, M.D., Audain, E., Dombrowsky, G., Banasik, K., Sifrim, A., Wilsdon, A., Thienpont, B., Breckpot, J., Gewillig, M., Brook, J.D., Hitz, M.P., Larsen, L.A. and Brunak, S.
Genome Medicine 12
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28 August 2020
Pharmacological characterization of the stick insect Carausius morosus allatostatin-C receptor with its endogenous agonist.
Işbilir, A., Duan Sahbaz, B., Tuncgenc, G., Bünemann, M., Lohse, M.J. and Birgül-Iyison, N.
ACS Omega 5
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22 December 2020
Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists.
Işbilir, A., Möller, J., Arimont, M., Bobkov, V., Perpiñá-Viciano, C., Hoffmann, C., Inoue, A., Heukers, R., de Graaf, C., Smit, M.J., Annibale, P. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 117
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17 November 2020
Factors associated with habitual time spent in different physical activity intensities using multiday accelerometry.
Jaeschke, L., Steinbrecher, A., Boeing, H., Gastell, S., Ahrens, W., Berger, K., Brenner, H., Ebert, N., Fischer, B., Greiser, K.H., Hoffmann, W., Jöckel, K.H., Kaaks, R., Keil, T., Kemmling, Y., Kluttig, A., Krist, L., Leitzmann, M., Lieb, W., Linseisen, J., Löffler, M., Michels, K.B., Obi, N., Peters, A., Schipf, S., Schmidt, B., Zinkhan, M. and Pischon, T.
Scientific Reports 10
: 774.
21 January 2020
Erfassung selbst berichteter kardiovaskulärer und metabolischer Erkrankungen in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse [Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].
Jaeschke, L., Steinbrecher, A., Greiser, K.H., Dörr, M., Buck, T., Linseisen, J., Meisinger, C., Ahrens, W., Becher, H., Berger, K., Braun, B., Brenner, H., Castell, S., Fischer, B., Franzke, C.W., Gastell, S., Günther, K., Hoffmann, W., Holleczek, B., Jagodzinski, A., Kaaks, R., Kluttig, A., Krause, G., Krist, L., Kuß, O., Lehnich, A.T., Leitzmann, M., Lieb, W., Löffler, M., Michels, K.B., Mikolajczyk, R., Peters, A., Schikowski, T., Schipf, S., Schmidt, B., Schulze, M., Völzke, H., Willich, S.N. and Pischon, T.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
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April 2020
Association of body surface scanner-based abdominal volume with parameters of the Metabolic Syndrome and comparison with manually measured waist circumference.
Jaeschke, L., Steinbrecher, A., Hansen, G., Sommer, S., Adler, C., Janke, J. and Pischon, T.
Scientific Reports 10
(1): 9324.
9 June 2020
Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.
Jahn, N., Terzer, T., Sträng, E., Dolnik, A., Cocciardi, S., Panina, E., Corbacioglu, A., Herzig, J., Weber, D., Schrade, A., Götze, K., Schröder, T., Lübbert, M., Wellnitz, D., Koller, E., Schlenk, R.F., Gaidzik, V.I., Paschka, P., Rücker, F.G., Heuser, M., Thol, F., Ganser, A., Benner, A., Döhner, H., Bullinger, L. and Döhner, K.
Blood Advances 4
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22 December 2020
Cbl-Associated Protein CAP contributes to correct formation and robust function of the Drosophila heart tube.
Jammrath, J., Reim, I. and Saumweber, H.
PLoS ONE 15
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29 May 2020
Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients.
Jarius, S., Lechner, C., Wendel, E.M., Baumann, M., Breu, M., Schimmel, M., Karenfort, M., Marina, A.D., Merkenschlager, A., Thiels, C., Blaschek, A., Salandin, M., Leiz, S., Leypoldt, F., Pschibul, A., Hackenberg, A., Hahn, A., Syrbe, S., Strautmanis, J., Häusler, M., Krieg, P., Eisenkölbl, A., Stoffels, J., Eckenweiler, M., Ayzenberg, I., Haas, J., Höftberger, R., Kleiter, I., Korporal-Kuhnke, M., Ringelstein, M., Ruprecht, K., Siebert, N., Schanda, K., Aktas, O., Paul, F., Reindl, M., Wildemann, B. and Rostásy, K.
Journal of Neuroinflammation 17
(1): 262.
3 September 2020
Neuromyelitis optica.
Jarius, S., Paul, F., Weinshenker, B.G., Levy, M., Kim, H.J. and Wildemann, B.
Nature Reviews Disease Primers 6
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22 October 2020
Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients.
Jarius, S., Pellkofer, H., Siebert, N., Korporal-Kuhnke, M., Hümmert, M.W., Ringelstein, M., Rommer, P.S., Ayzenberg, I., Ruprecht, K., Klotz, L., Asgari, N., Zrzavy, T., Höftberger, R., Tobia, R., Buttmann, M., Fechner, K., Schanda, K., Weber, M., Asseyer, S., Haas, J., Lechner, C., Kleiter, I., Aktas, O., Trebst, C., Rostasy, K., Reindl, M., Kümpfel, T., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 17
(1): 261.
3 September 2020
Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Jayavelu, A.K., Schnöder, T.M., Perner, F., Herzog, C., Meiler, A., Krishnamoorthy, G., Huber, N., Mohr, J., Edelmann-Stephan, B., Austin, R., Brandt, S., Palandri, F., Schröder, N., Isermann, B., Edlich, F., Sinha, A.U., Ungelenk, M., Hübner, C.A., Zeiser, R., Rahmig, S., Waskow, C., Coldham, I., Ernst, T., Hochhaus, A., Jilg, S., Jost, P.J., Mullally, A., Bullinger, L., Mertens, P.R., Lane, S.W., Mann, M. and Heidel, F.H.
Nature 588
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3 December 2020
Akzeptanz der Übertragung ärztlicher Tätigkeiten an Medizinische Fachangestellte: Ergebnisse einer repräsentativen Versichertenbefragung der Kassenärztlichen Bundesvereinigung [The acceptability of task-shifting from doctors to allied health professionals: results from a representative telephone survey of members of the National Association of Statutory Health Insurance Physicians].
Jedro, C., Holmberg, C., Tille, F., Widmann, J., Schneider, A., Stumm, J., Döpfmer, S., Kuhlmey, A. and Schnitzer, S.
Deutsches Aerzteblatt 117
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31 August 2020
The acceptability of task-shifting from doctors to allied health professionals - results from a representative telephone survey of members of the National Association of Statutory Health Insurance Physicians.
Jedro, C., Holmberg, C., Tille, F., Widmann, J., Schneider, A., Stumm, J., Döpfmer, S., Kuhlmey, A. and Schnitzer, S.
Deutsches Aerzteblatt International 117
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31 August 2020
Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions.
Jeuthe, S., Kemna, J., Kemna, C.P., Zocholl, D., Klopfleisch, R., Palme, R., Kirschbaum, C., Thoene-Reineke, C. and Kammertoens, T.
PLoS ONE 15
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30 September 2020
Impact of intercellular crosstalk between epidermal keratinocytes and dermal fibroblasts on skin homeostasis.
Jevtić, M., Löwa, A., Nováčková, A., Kováčik, A., Kaessmeyer, S., Erdmann, G., Vávrová, K. and Hedtrich, S.
Biochimica et Biophysica Acta - Molecular Cell Research 1867
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August 2020
Controlled release of therapeutics from thermoresponsive
nanogels: a thermal magnetic resonance feasibility study.
Ji, Y., Winter, L., Navarro, L., Ku, M.C., Periquito, J.S., Pham, M., Hoffmann, W., Theune, L.E., Calderón, M. and Niendorf, T.
Cancers 12
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27 May 2020
MCH neurons regulate permeability of the median eminence barrier.
Jiang, H., Gallet, S., Klemm, P., Scholl, P., Folz-Donahue, K., Altmüller, J., Alber, J., Heilinger, C., Kukat, C., Loyens, A., Müller-Fielitz, H., Sundaram, S., Schwaninger, M., Prevot, V. and Brüning, J.C.
Neuron 107
(2): 306-319.
22 July 2020
Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.
Jiang, S., Penack, O., Terzer, T., Schult, D., Majer-Lauterbach, J., Radujkovic, A., Blau, I.W., Bullinger, L., Müller-Tidow, C., Dreger, P. and Luft, T.
Haematologica 106
(2): 446-453.
February 2020
The integrated RNA landscape of renal preconditioning against ischemia-reperfusion injury.
Johnsen, M., Kubacki, T., Yeroslaviz, A., Späth, M.R., Mörsdorf, J., Göbel, H., Bohl, K., Ignarski, M., Meharg, C., Habermann, B., Altmüller, J., Beyer, A., Benzing, T., Schermer, B., Burst, V. and Müller, R.U.
Journal of the American Society of Nephrology 31
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April 2020
Optic chiasm measurements may be useful markers of anterior optic pathway degeneration in neuromyelitis optica spectrum disorders.
Juenger, V., Cooper, G., Chien, C., Chikermane, M., Oertel, F.C., Zimmermann, H., Ruprecht, K., Jarius, S., Siebert, N., Kuchling, J., Papadopoulou, A., Asseyer, S., Bellmann-Strobl, J., Paul, F., Brandt, A.U. and Scheel, M.
European Radiology 30
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September 2020
Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes.
Jumaa, H., Caganova, M., McAllister, E.J., Hoenig, L., He, X., Saltukoglu, D., Brenker, K., Köhler, M., Leben, R., Hauser, A.E., Niesner, R., Rajewsky, K., Reth, M. and Jellusova, J.
Life Science Alliance 3
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June 2020
Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1.
Jupp, B., Pitzoi, S., Petretto, E., Mar, A.C., Oliver, Y.P., Jordan, E.R., Taylor, S., Atanur, S.S., Srivastava, P.K., Saar, K., Hubner, N., Sommer, W.H., Staehlin, O., Spanagel, R., Robinson, E.S., Schumann, G., Moreno, M., Everitt, B.J., Robbins, T.W., Aitman, T.J. and Dalley, J.W.
Scientific Reports 10
(1): 6684.
21 April 2020
Mendelian randomization study on amino acid metabolism suggests tyrosine as causal trait for type 2 diabetes.
Jäger, S., Cuadrat, R., Wittenbecher, C., Floegel, A., Hoffmann, P., Prehn, C., Adamski, J., Pischon, T. and Schulze, M.B.
Nutrients 12
(12): 3890.
19 December 2020
Angiotensin-(1-7) receptor Mas deficiency does not exacerbate cardiac atrophy following high-level spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S., Alenina, N. and Bader, M.
Frontiers in Physiology 11
: 203.
12 March 2020
Angiotensin‐II receptor type Ia does not contribute to cardiac atrophy following high‐thoracic spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S. and Bader, M.
Experimental Physiology 105
(8): 1316-1325.
1 August 2020
Identification of miR-21-5p and miR-210-3p serum levels as biomarkers for patients with papillary renal cell carcinoma: a multicenter analysis.
Kalogirou, C., Ellinger, J., Kristiansen, G., Hatzichristodoulou, G., Kübler, H., Kneitz, B., Busch, J. and Fendler, A.
Translational Andrology and Urology 9
(3): 1314-1322.
June 2020
A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection.
Kaminski, M.M., Alcantar, M.A., Lape, I.T., Greensmith, R., Huske, A.C., Valeri, J.A., Marty, F.M., Klämbt, V., Azzi, J., Akalin, E., Riella, L.V. and Collins, J.J.
Nature Biomedical Engineering 4
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June 2020
Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Kapp-Schwoerer, S., Weber, D., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Krönke, J., Theis, F., Rücker, F.G., Teleanu, M.V., Panina, E., Jahn, N., Herzig, J., Kubanek, L., Schrade, A., Göhring, G., Fiedler, W., Kindler, T, Schroeder, T., Mayer, K.T., Lübbert, M., Wattad, M., Götze, K.S., Horst, H.A., Koller, E., Wulf, G., Schleicher, J., Bentz, M., Krauter, J., Bullinger, L., Krzykalla, J., Benner, A., Schlenk, R.F., Thol, F., Heuser, M., Ganser, A., Döhner, H and Döhner, K.
Blood 136
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24 December 2020
Lungenfunktion in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse [Lung function in the German National Cohort: methods and initial results].
Karrasch, S., Peters, A., Meisinger, C., Ferland, M., Jaeschke, L., Pischon, T., Fricke, J., Keil, T., Gastell, S., Schulze, M., Brandes, M., Günther, K., Kuß, O., Schikowski, T., Emmel, C., Jöckel, K.H., Michels, K.B., Franzke, C.W., Langer, S., Mikolajczyk, R., Jagodzinski, A., Becher, H., Castell, S., Kemmling, Y., Waniek, S., Lieb, W., Wirkner, K., Loeffler, M., Greiser, K.H., Kaaks, R., Legath, N., Berger, K., Schipf, S., Hoffmann, W., Sedlmeier, A., Leitzmann, M., Brenner, H., Holleczek, B. and Schulz, H.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(3): 322-331.
March 2020
Assessment of diastolic dysfunction: comparison of different cardiovascular magnetic resonance techniques.
Kermer, J., Traber, J., Utz, W., Hennig, P., Menza, M., Jung, B., Greiser, A., Barckow, P., von Knobelsdorff-Brenkenhoff, F., Töpper, A., Blaszczyk, E. and Schulz-Menger, J.
ESC Heart Failure 7
(5): 2637-2649.
October 2020
A single amino acid switch converts the sleeping beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.
Kesselring, L., Miskey, C., Zuliani, C., Querques, I., Kapitonov, V., Laukó, A., Fehér, A., Palazzo, A., Diem, T., Lustig, J., Sebe, A., Wang, Y., Dinnyés, A., Izsvák, Z., Barabas, O. and Ivics, Z.
Nucleic Acids Research 48
(1): 316-331.
1 January 2020
Hyperkalzämie [Hypercalcemia].
Kettritz, R.
Deutsche Medizinische Wochenschrift 145
(3): 171-174.
February 2020
CRISPLD1: a novel conserved target in the transition to human heart failure.
Khadjeh, S., Hindmarsh, V., Weber, F., Cyganek, L., Vidal, R.O., Torkieh, S., Streckfuss-Bömeke, K., Lbik, D., Tiburcy, M., Mohamed, B.A., Bonn, S., Toischer, K. and Hasenfuss, G.
Basic Research in Cardiology 115
(3): 27.
7 March 2020
AKI-Alerts.
Khadzhynov, D., Schmidt, D. and Schmidt-Ott, K.
Dialyse aktuell 24
(7): 265-269.
September 2020
PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity.
Kim, H., Kim, H., Feng, Y., Li, Y., Tamiya, H., Tocci, S. and Ronai, Z.A.
Science Translational Medicine 12
(551): eaaz5683.
8 July 2020
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.
Kim, H., Nguyen, N.P., Turner, K., Wu, S., Gujar, A.D., Luebeck, J., Liu, J., Deshpande, V., Rajkumar, U., Namburi, S., Amin, S.B., Yi, E., Menghi, F., Schulte, J.H., Henssen, A.G., Chang, H.Y., Beck, C.R., Mischel, .S., Bafna, V. and Verhaak, R.G.W.
Nature Genetics 52
(9): 891-897.
September 2020
Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M., Franke, V., Brandt, B., Lowenstein, E.D., Schöwel, V., Spuler, S., Akalin, A. and Birchmeier, C.
Nature Communications 11
: 6375.
11 December 2020
Epigenetic reader BRD4 (Bromodomain-Containing Protein 4) governs nucleus-encoded mitochondrial transcriptome to regulate cardiac function.
Kim, S.Y., Zhang, X., Schiattarella, G.G., Altamirano, F., Ramos, T.A.R., French, K.M., Jiang, N., Szweda, P.A., Evers, B.M., May, H.I., Luo, X., Li, H., Szweda, L.I., Maracaja-Coutinho, V., Lavandero, S., Gillette, T.G. and Hill, J.A.
Circulation 142
(24): 2356-2370.
15 December 2020
The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models.
Klems, A., van Rijssel, J., Ramms, A.S., Wild, R., Hammer, J., Merkel, M., Derenbach, L., Préau, L., Hinkel, R., Suarez-Martinez, I., Schulte-Merker, S., Vidal, R., Sauer, S., Kivelä, R., Alitalo, K., Kupatt, C., van Buul, J.D. and le Noble, F.
Nature Communications 11
(1): 5319.
21 October 2020
Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer.
Klinghammer, K., Politz, O., Eder, T., Otto, R., Raguse, J.D., Albers, A., Kaufmann, A., Tinhofer, I., Hoffmann, J., Keller, U. and Keilholz, U.
Oncotarget 11
(41): 3688-3697.
13 October 2020
Messung der körperlichen Fitness in der NAKO Gesundheitsstudie – Methoden, Qualitätssicherung und erste deskriptive Ergebnisse [Measuring physical fitness in the German National Cohort-methods, quality assurance, and first descriptive results].
Kluttig, A., Zschocke, J., Haerting, J., Schmermund, A., Gastell, S., Steindorf, K., Herbolsheimer, F., Hillreiner, A., Jochem, C., Baumeister, S., Sprengeler, O., Pischon, T., Jaeschke, L., Michels, K.B., Krist, L., Greiser, H., Schmidt, G., Lieb, W., Waniek, S., Becher, H., Jagodzinski, A., Schipf, S., Völzke, H., Ahrens, W., Günther, K., Castell, S., Kemmling, Y., Legath, N., Berger, K., Keil, T., Fricke, J., Schulze, M.B., Loeffler, M., Wirkner, K., Kuß, O., Schikowski, T., Kalinowski, S., Stang, A., Kaaks, R., Damms Machado, A., Hoffmeister, M., Weber, B., Franzke, C.W., Thierry, S., Peters, A., Kartschmit, N., Mikolajczyk, R., Fischer, B., Leitzmann, M. and Brandes, M.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(3): 312-321.
March 2020
Pro-inflammatory TNF-α and IFN-γ promote tumor growth and metastasis via induction of MACC1.
Kobelt, D., Zhang, C., Clayton-Lucey, I.A., Glauben, R., Voss, C., Siegmund, B. and Stein, U.
Frontiers in Immunology 11
: 980.
27 May 2020
Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity.
Koch, C., Kuske, A., Joosse, S.A., Yigit, G., Sflomos, G., Thaler, S., Smit, D.J., Werner, S., Borgmann, K., Gärtner, S., Mossahebi Mohammadi, P., Battista, L., Cayrefourcq, L., Altmüller, J., Salinas-Riester, G., Raithatha, K., Zibat, A., Goy, Y., Ott, L., Bartkowiak, K., Tan, T.Z., Zhou, Q., Speicher, M.R., Müller, V., Gorges, T.M., Jücker, M., Thiery, J.P., Brisken, C., Riethdorf, S., Alix-Panabières, C. and Pantel, K.
EMBO Molecular Medicine 12
(9): e11908.
7 September 2020
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Koche, R.P., Rodriguez-Fos, E., Helmsauer, K., Burkert, M., MacArthur, I.C., Maag, J., Chamorro, R., Munoz-Perez, N., Puiggròs, M., Dorado Garcia, H., Bei, Y., Röefzaad, C., Bardinet, V., Szymansky, A., Winkler, A., Thole, T., Timme, N., Kasack, K., Fuchs, S., Klironomos, F., Thiessen, N., Blanc, E., Schmelz, K., Künkele, A., Hundsdörfer, P., Rosswog, C., Theissen, J., Beule, D., Deubzer, H., Sauer, S., Toedling, J., Fischer, M., Hertwig, F., Schwarz, R.F., Eggert, A., Torrents, D., Schulte, J.H. and Henssen, A.G.
Nature Genetics 52
(1): 29-34.
January 2020
Powerful rare variant association testing in a copula-based joint analysis of multiple phenotypes.
Konigorski, S., Yilmaz, Y.E., Janke, J., Bergmann, M.M., Boeing, H. and Pischon, T.
Genetic Epidemiology 44
(1): 26-40.
January 2020
A systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics.
Konrath, F., Mittermeier, A., Cristiano, E., Wolf, J. and Loewer, A.
PLoS Computational Biology 16
(6): e1007901.
26 June 2020
Deep learning for genomics using Janggu.
Kopp, W., Monti, R., Tamburrini, A., Ohler, U. and Akalin, A.
Nature Communications 11
(1): 3488.
13 July 2020
Human cerebrospinal fluid monoclonal LGI1 autoantibodies increase neuronal excitability.
Kornau, H.C., Kreye, J., Stumpf, A., Fukata, Y., Parthier, D., Sammons, R.P., Imbrosci, B., Kurpjuweit, S., Kowski, A.B., Fukata, M., Prüss, H. and Schmitz, D.
Annals of Neurology 87
(3): 405-418.
March 2020
Z-score mapping for standardized analysis and reporting of cardiovascular magnetic resonance modified Look-Locker inversion recovery (MOLLI) T1 data: normal behavior and validation in patients with amyloidosis.
Kranzusch, R., Aus dem Siepen, F., Wiesemann, S., Zange, L., Jeuthe, S., Ferreira da Silva, T., Kuehne, T., Pieske, B., Tillmanns, C., Friedrich, M.G., Schulz-Menger, J. and Messroghli, D.R.
Journal of Cardiovascular Magnetic Resonance 22
(1): 6.
20 January 2020
The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled.
Kratzer, M.C., Becker, S.F.S., Grund, A., Merks, A., Harnoš, J., Bryja, V., Giehl, K., Kashef, J. and Borchers, A.
Development 147
(10): dev186338.
22 May 2020
Renin-Angiotensin-System (RAS) und COVID-19 – Zur Verordnung von RAS-Blockern [Renin-angiotensin-system (RAS) and COVID-19 – on the prescription of RAS blockers].
Kreutz, R., Abd El-Hady Algharably, E., Ganten, D. and Messerli, F.
Deutsche Medizinische Wochenschrift 145
(10): 682-686.
May 2020
A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model.
Kreye, J., Reincke, S.M., Kornau, H.C., Sánchez-Sendin, E., Corman, V.M., Liu, H., Yuan, M., Wu, N.C., Zhu, X., Lee, C.C.D., Trimpert, J., Höltje, M., Dietert, K., Stöffler, L., von Wardenburg, N., van Hoof, S., Homeyer, M.A., Hoffmann, J., Abdelgawad, A., Gruber, A.D., Bertzbach, L.D., Vladimirova, D., Li, L.Y., Barthel, P.C., Skriner, K., Hocke, A.C., Hippenstiel, S., Witzenrath, M., Suttorp, N., Kurth, F., Franke, C., Endres, M., Schmitz, D., Jeworowski, L.M., Richter, A., Schmidt, M.L., Schwarz, T., Müller, M.A., Drosten, C., Wendisch, D., Sander, L.E., Osterrieder, N., Wilson, I.A. and Prüss, H.
Cell 183
(4): 1058-1069.
12 November 2020
Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Kroschinsky, F., Middeke, J.M., Janz, M., Lenz, G., Witzens-Harig, M., Bouabdallah, R., La Rosée, P., Viardot, A., Salles, G., Kim, S.J., Kim, T.M., Ottmann, O., Chromik, J., Quinson, A.M., von Wangenheim, U., Burkard, U., Berk, A. and Schmitz, N.
Investigational New Drugs 38
(5): 1472-1482.
October 2020
Proteogenomic landscape of breast cancer tumorigenesis and targeted therapy.
Krug, K., Jaehnig, E.J., Satpathy, S., Blumenberg, L., Karpova, A., Anurag, M., Miles, G., Mertins, P., Geffen, Y., Tang, L.C., Heiman, D.I., Cao, S., Maruvka, Y.E., Lei, J.T., Huang, C., Kothadia, R.B., Colaprico, A., Birger, C., Wang, J., Dou, Y., Wen, B., Shi, Z., Liao, Y., Wiznerowicz, M., Wyczalkowski, M.A., Chen, X.S., Kennedy, J.J., Paulovich, A.G., Thiagarajan, M., Kinsinger, C.R., Hiltke, T., Boja, E.S., Mesri, M., Robles, A.I., Rodriguez, H., Westbrook, T.F., Ding, L., Getz, G., Clauser, K.R., Fenyö, D., Ruggles, K.V., Zhang, B., Mani, D.R, Carr, S.A., Ellis, M.J. and Gillette, M.A.
Cell 183
(5): 1436-1456.
25 November 2020
Artificial-intelligence-driven scanning probe microscopy.
Krull, A., Hirsch, P., Rother, C., Schiffrin, A. and Krull, C.
Communications Physics 3
(1): 54.
19 March 2020
Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes.
Kräker, K., Herse, F., Golic, M., Reichhart, N., Crespo-Garcia, S., Straß, O., Grune, J., Kintscher, U., Ebrahim, M., Bader, M., Alenina, N., Heuser, A., Luft, F.C., Müller, D.N., Dechend, R. and Haase, N.
Scientific Reports 10
(1): 14061.
20 August 2020
Statins reverse postpartum cardiovascular dysfunction in a rat model of preeclampsia.
Kräker, K., O'Driscoll, J.M., Schütte, T., Herse, F., Patey, O., Golic, M., Geisberger, S., Verlohren, S., Birukov, A., Heuser, A., Mueller, D.N., Thilaganathan, B., Dechend, R. and Haase, N.
Hypertension 75
(1): 202-210.
January 2020
Speckle tracking echocardiography: new ways of translational approaches in preeclampsia to detect cardiovascular dysfunction.
Kräker, K., Schütte, T., O'Driscoll, J., Birukov, A., Patey, O., Herse, F., Mueller, D.N., Thilaganathan, B., Haase, N. and Dechend, R.
International Journal of Molecular Sciences 21
(3): 1162.
10 February 2020
Cell type-specific transcriptomics of esophageal adenocarcinoma as a scalable alternative for single cell transcriptomics.
Krämer, M., Plum, P.S., Velazquez Camacho, O., Folz-Donahue, K., Thelen, M., Garcia-Marquez, I., Wölwer, C., Büsker, S., Wittig, J., Franitza, M., Altmüller, J., Löser, H., Schlößer, H., Büttner, R., Schröder, W., Bruns, C.J., Alakus, H., Quaas, A., Chon, S.H. and Hillmer, A.M.
Molecular Oncology 14
(6): 1170-1184.
June 2020
Solving the time- and frequency-multiplexed problem of constrained radiofrequency induced hyperthermia.
Kuehne, A., Oberacker, E., Waiczies, H. and Niendorf, T.
Cancers 12
(5): 1072.
May 2020
TaxIt: an iterative computational pipeline for untargeted strain-level identification using MS/MS spectra from pathogenic single-organism samples.
Kuhring, M., Doellinger, J., Nitsche, A., Muth, T. and Renard, B.Y.
Journal of Proteome Research 19
(6): 2501-2510.
5 June 2020
Concepts and software package for efficient quality control in targeted metabolomics studies - MeTaQuaC.
Kuhring, M., Eisenberger, A., Schmidt, V., Kränkel, N., Leistner, D.M., Kirwan, J. and Beule, D.
Analytical Chemistry 92
(15): 10241-10245.
4 August 2020
The clinical effect of probiotic-containing product on health indicators among a population of Central Asia.
Kushugulova, A.R., Forslund, S.K., Kozhakhmetov, S.S., Kairov, U.E., Molkenov, A.B., Sergazy, S.D., Saduakhassova, S.A., Urazbayeva, G.S., Beysembayeva, S.C., Karabaeva, R.Z., Bakenova, R.A., Nurgozhin, T.S., Benberin, V.V., Zhumadilov, Z.S. and Bork, P.
Science & Healthcare 22
(2): 49-60.
30 April 2020
Murine cytomegalovirus M25 proteins sequester the tumor suppressor protein p53 in nuclear accumulations.
Kutle, I., Szymańska-de Wijs, K.M., Bogdanow, B., Cuvalo, B., Steinbrück, L., Jonjić, S., Wagner, K., Niedenthal, R., Selbach, M., Wiebusch, L., Dezeljin, M. and Messerle, M.
Journal of Virology 94
(20): e00574-20.
October 2020
Human lipoxygenase isoforms form complex patterns of double and triple oxygenated compounds from eicosapentaenoic acid.
Kutzner, L., Goloshchapova, K., Rund, K.M., Jübermann, M., Blum, M., Rothe, M., Kirsch, S.F., Schunck, W.H., Kühn, H. and Schebb, N.H.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1865
(12): 158806.
December 2020
Microscopy with undetected photons in the mid-infrared.
Kviatkovsky, I., Chrzanowski, H.M., Avery, E.G., Bartolomaeus, H. and Ramelow, S.
Science Advances 6
(42): eabd0264.
14 October 2020
Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery.
Laidou, S., Alanis-Lobato, G., Pribyl, J., Raskó, T., Tichy, B., Mikulasek, K., Tsagiopoulou, M., Oppelt, J., Kastrinaki, G., Lefaki, M., Singh, M., Zink, A., Chondrogianni, N., Psomopoulos, F., Prigione, A., Ivics, Z., Pospisilova, S., Skladal, P., Izsvák, Z., Andrade-Navarro, M.A. and Petrakis, S.
Redox Biology 32
: 101458.
May 2020
Commentary on a combined approach to the problem of developing biomarkers for the prediction of spontaneous preterm labor that leads to preterm birth.
Lamont, R.F., Richardson, L.S., Boniface, J.J., Cobo, T., Exner, M.M., Christensen, I.B., Forslund, S.K., Gaba, A., Helmer, H., Jørgensen, J.S., Khan, R.N., McElrath, T.F., Petro, K., Rasmussen, M., Singh, R., Tribe, R.M., Vink, J.S., Vinter, C.A., Zhong, N. and Menon, R.
Placenta 98
: 13-23.
1 September 2020
Support of a molecular tumour board by an evidence-based decision management system for precision oncology.
Lamping, M., Benary, M., Leyvraz, S., Messerschmidt, C., Blanc, E., Kessler, T., Schütte, M., Lenze, D., Jöhrens, K., Burock, S., Klinghammer, K., Ochsenreither, S., Sers, C., Schäfer, R., Tinhofer, I., Beule, D., Klauschen, F., Yaspo, M.L., Keilholz, U. and Rieke, D.T.
European Journal of Cancer 127
: 41-51.
March 2020
Subcellular localization and formation of huntingtin aggregates correlates with symptom onset and progression in a Huntington's disease model.
Landles, C., Milton, R.E., Ali, N., Flomen, R., Flower, M., Schindler, F., Gomez-Paredes, C., Bondulich, M.K., Osborne, G.F., Goodwin, D., Salsbury, G., Benn, C.L., Sathasivam, K., Smith, E.J., Tabrizi, S.J., Wanker, E.E. and Bates, G.P.
Brain Communications 2
(2): fcaa066.
3 August 2020
Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting.
Lang, K.M., Harrison, K.L., Williamson, P.R., Huntly, B.J.P., Ossenkoppele, G., Geissler, J., Bereczky, T., Hernández-Rivas, J.M., Chevrou-Séverac, H., Goodbody, R., Schulze-Rath, R. and Bullinger, L.
Trials 21
(1): 437.
27 May 2020
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates.
Langer, H.T., Afzal, S., Kempa, S. and Spuler, S.
Scientific Reports 10
: 1908.
5 February 2020
Häufigkeit von Asthma bronchiale und Alter bei der Erstdiagnose - erste Ergebnisse der NAKO Gesundheitsstudie [Occurrence of bronchial asthma and age at initial asthma diagnosis-first results of the German National Cohort].
Langer, S., Horn, J., Kluttig, A., Mikolajczyk, R., Karrasch, S., Schulz, H., Wichmann, H.E., Linseisen, J., Jaeschke, L., Pischon, T., Fricke, J., Keil, T., Ahrens, W., Günther, K., Kuß, O., Schikowski, T., Schmidt, B., Jöckel, K.H., Michels, K.B., Franzke, C.W., Becher, H., Jagodzinski, A., Castell, S., Kemmling, Y., Lieb, W., Waniek, S., Wirkner, K., Löffler, M., Kaaks, R., Greiser, K.H., Berger, K., Legath, N., Meinke-Franze, C., Schipf, S., Leitzmann, M., Baurecht, H., Weigl, K., Amitay, E. and Gottschick, C.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(4): 397-403.
April 2020
Targeting the ubiquitin-proteasome system in a pancreatic cancer subtype with hyperactive MYC.
Lankes, K., Hassan, Z.Z., Doffo, M.J., Schneeweis, C., Lier, S., Öllinger, R., Rad, R., Krämer, O.H., Keller, U., Saur, D., Reichert, M., Schneider, G. and Wirth, M.
Molecular Oncology 14
(12): 3048-3064.
December 2020
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.
Lauber, C., Correia, N., Trumpp, A., Rieger, M.A., Dolnik, A., Bullinger, L., Roeder, I. and Seifert, M.
Scientific Reports 10
(1): 12761.
29 July 2020
Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer.
Le Poul, Y., Xin, Y., Ling, L., Mühling, B., Jaenichen, R., Hörl, D., Bunk, D., Harz, H., Leonhardt, H., Wang, Y., Osipova, E., Museridze, M., Dharmadhikari, D., Murphy, E., Rohs, R., Preibisch, S., Prud'homme, B. and Gompel, N.
Science Advances 6
(49): eabe2955.
2 December 2020
Cortical cells are altered by factors including bone morphogenetic protein released from a placental barrier model under altered oxygenation.
Leinster, V.H.L., Phillips, T.J., Jones, N., Sanderson, S., Simon, K., Hanley, J. and Case, C.P.
Neuronal Signaling 4
(1): NS20190148.
April 2020
Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study.
Leistner, D.M., Kränkel, N., Meteva, D., Abdelwahed, Y.S., Seppelt, C., Stähli, B.E., Rai, H., Skurk, C., Lauten, A., Mochmann, H.C., Fröhlich, G., Rauch-Kröhnert, U., Flores, E., Riedel, M., Sieronski, L., Kia, S., Strässler, E., Haghikia, A., Dirks, F., Steiner, J. K., Mueller, D.N., Volk, H.D., Klotsche, J., Joner, M., Libby, P. and Landmesser, U.
European Heart Journal 41
(37): 3549-3560.
20 October 2020
Körperliche Aktivität in der NAKO Gesundheitsstudie: erste Ergebnisse des multimodalen Erhebungskonzepts [Physical activity in the German National Cohort (NAKO): use of multiple assessment tools and initial results].
Leitzmann, M., Gastell, S., Hillreiner, A., Herbolsheimer, F., Baumeister, S.E., Bohn, B., Brandes, M., Greiser, H., Jaeschke, L., Jochem, C., Kluttig, A., Krist, L., Michels, K.B., Pischon, T., Schmermund, A., Sprengeler, O., Zschocke, J., Ahrens, W., Baurecht, H., Becher, H., Berger, K., Brenner, H., Castell, S., Fischer, B., Franzke, C.W., Fricke, J., Hoffmann, W., Holleczek, B., Kaaks, R., Kalinowski, S., Keil, T., Kemmling, Y., Kuß, O., Legath, N., Lieb, W., Linseisen, J., Löffler, M., Mikolajczyk, R., Obi, N., Peters, A., Ratjen, I., Schikowski, T., Schulze, M.B., Stang, A., Thierry, S., Völzke, H., Wirkner, K. and Steindorf, K.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 6
(3): 301-311.
March 2020
Multiplex analysis of circulating maternal cardiovascular biomarkers comparing preeclampsia subtypes.
Lekva, T., Sugulle, M., Moe, K., Redman, C., Dechend, R. and Staff, A.C.
Hypertension 75
(6): 1513-1522.
June 2020
The chloroplast RNA binding protein CP31A has a preference for mRNAs encoding the subunits of the chloroplast NAD(P)H dehydrogenase complex and is required for their accumulation.
Lenzen, B., Rühle, T., Lehniger, M.K., Okuzaki, A., Labs, M., Muino, J.M., Ohler, U., Leister, D. and Schmitz-Linneweber, C.
International Journal of Molecular Sciences 21
(16): 5633.
6 August 2020
The predictive value of urinary kidney injury molecular 1 for the diagnosis of contrast-induced acute kidney injury after cardiac catheterization: a meta-analysis.
Li, Q., Huang, Y., Shang, W., Zhang, Y., Liu, Y. and Xu, G.
Journal of Interventional Cardiology 2020
: 4982987.
14 August 2020
Identification of metabolites from tandem mass spectra with a machine learning approach utilizing structural features.
Li, Y., Kuhn, M., Gavin, A.C. and Bork, P.
Bioinformatics 36
(4): 1213-1218.
15 February 2020
A comprehensive monitoring study on electrocardiographic assessments and cardiac events after fingolimod first dose - possible predictors of cardiac outcomes.
Limmroth, V., Ziemssen, T., Kleiter, I., Wagner, B., Schmidt, S., Lassek, C., Baier-Ebert, M., Wendt, G., Dechend, R. and Haverkamp, W.
Frontiers in Neurology 11
: 818.
12 August 2020
Who with whom: functional coordination of E2 enzymes by RING E3 ligases during poly-ubiquitylation.
Lips, C., Ritterhoff, T., Weber, A., Janowska, M.K., Mustroph, M., Sommer, T. and Klevit, R.E.
EMBO Journal 39
(22): e104863.
16 November 2020
Hypochlorhydria reduces mortality in heart failure caused by Kcne2 gene deletion.
Lisewski, U., Köhncke, C., Schleussner, L., Purfürst, B., Lee, S.M., De Silva, A., Manville, R.W., Abbott, G.W. and Roepke, T.K.
FASEB Journal 34
(8): 10699-10719.
August 2020
Cells of the adult human heart.
Litviňuková, M., Talavera-López, C., Maatz, H., Reichart, D., Worth, C.L., Lindberg, E.L., Kanda, M., Polanski, K., Heinig, M., Lee, M.l, Nadelmann, E.R., Roberts, K., Tuck, L., Fasouli, E.S., DeLaughter, D.M., McDonough, B., Wakimoto, H., Gorham, J.M., Samari, S., Mahbubani, K.T., Saeb-Parsy, K., Patone, G., Boyle, J.J., Zhang, H., Zhang, H., Viveiros, A., Oudit, G.Y., Bayraktar, O., Seidman, J.G., Seidman, C.E., Noseda, M., Hubner, N. and Teichmann, S.A.
Nature 588
(7838): 466-472.
17 December 2020
Social media big data-based research on the influencing factors of insomnia and spatiotemporal evolution.
Liu, Y., Luo, Q., Shen, H., Zhuang, S., Xu, C., Dong, Y., Sun, Y., Wang, S. and Deng, H.
IEEE Access 8
: 41516-41529.
28 February 2020
NNT-AS1 enhances bladder cancer cell growth by targeting miR-1301-3p/PODXL axis and activating Wnt pathway.
Liu, Y. and Wu, G.
Neurourology and Urodynamics 39
(2): 547-557.
February 2020
Consensus-based technical recommendations for clinical translation of renal diffusion-weighted MRI.
Ljimani, A., Caroli, A., Laustsen, C., Francis, S., Mendichovszky, I.A., Bane, O., Nery, F., Sharma, K., Pohlmann, A., Dekkers, I.A., Vallee, J.P., Derlin, K., Notohamiprodjo, M., Lim, R.P., Palmucci, S., Serai, S.D., Periquito, J., Wang, Z.J., Froeling, M., Thoeny, H.C., Prasad, P., Schneider, M., Niendorf, T., Pullens, P., Sourbron, S. and Sigmund, E.E.
Magnetic Resonance Materials in Physics Biology and Medicine 33
(1): 177-195.
February 2020
Getting CD19 into shape: expression of natively folded "difficult-to-express" CD19 for staining and stimulation of CAR-T cells.
Lobner, E., Wachernig, A., Gudipati, V., Mayrhofer, P., Salzer, B., Lehner, M., Huppa, J.B. and Kunert, R.
Frontiers in Bioengineering and Biotechnology 8
: 49.
7 February 2020
Lineage commitment of hematopoietic stem cells and progenitors: insights from recent single cell and lineage tracing technologies.
Loughran, S.J., Haas, S., Wilkinson, A.C., Klein, A.M. and Brand, M.
Experimental Hematology 88
: 1-6.
August 2020
School- and leisure time factors are associated with sitting time of German and Irish children and adolescents during school: results of a DEDIPAC feasibility study.
Lubasch, J.S., Thumann, B., Bucksch, J., Brackmann, L.K., Wirsik, N., Donnelly, A., Hayes, G., Nimptsch, K., Steinbrecher, A., Pischon, T., Brug, J., Ahrens, W. and Hebestreit, A.
Frontiers in Sports and Active Living 2
: 93.
23 July 2020
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik, P., Baude, A., Mancarella, D., Öz, S., Kühn, A., Toth, R., Hey, J., Toprak, U.H., Lim, J., Nguyen, V.H., Jiang, C., Mayakonda, A., Hartmann, M., Rosemann, F., Breuer, K., Vonficht, D., Grünschläger, F., Lee, S., Schuhmacher, M.K., Kusevic, D., Jauch, A., Weichenhan, D., Zustin, J., Schlesner, M., Haas, S., Park, J.H., Park, Y.J., Oppermann, U., Jeltsch, A., Haller, F., Fellenberg, J., Lindroth, A.M. and Plass, C.
Nature Communications 11
(1): 5414.
27 October 2020
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
López, S., Lim, E.L., Horswell, S., Haase, K., Huebner, A., Dietzen, M., Mourikis, T.P., Watkins, T.B.K., Rowan, A., Dewhurst, S.M., Birkbak, N.J., Wilson, G.A., Van Loo, P., Jamal-Hanjani, M., Swanton, C. and McGranahan, N.
Nature Genetics 52
(3): 283-293.
March 2020
Single-cell strand sequencing of a macaque genome reveals multiple nested inversions and breakpoint reuse during primate evolution.
Maggiolini, F.A.M., Sanders, A.D., Shew, C.J., Sulovari, A., Mao, Y., Puig, M., Catacchio, C.R., Dellino, M., Palmisano, D., Mercuri, L., Bitonto, M., Porubský, D., Cáceres, M., Eichler, E.E., Ventura, M., Dennis, M.Y., Korbel, J.O. and Antonacci, F.
Genome Research 30
(11): 1680-1693.
November 2020
Hypoxia and exercise interactions on skeletal muscle insulin sensitivity in obese subjects with metabolic syndrome: results of a randomized controlled trial.
Mai, K., Klug, L., Rakova, N., Piper, S.K., Mähler, A., Bobbert, T., Schulz-Menger, J., Spranger, J., Boschmann, M. and Luft, F.C.
International Journal of Obesity 44
(5): 1119-1128.
May 2020
PatchPerPix for instance segmentation.
Mais, L., Hirsch, P. and Kainmueller, D.
Lecture Notes in Computer Science 12370
: 288-304.
20 November 2020
Disentangling the impact of environmental and phylogenetic constraints on prokaryotic within-species diversity.
Maistrenko, O.M., Mende, D.R., Luetge, M., Hildebrand, F., Schmidt, T.S.B., Li, S.S., Rodrigues, J.F.M., von Mering, C., Pedro Coelho, L., Huerta-Cepas, J., Sunagawa, S. and Bork, P.
ISME Journal 14
(5): 1247-1259.
May 2020
MyoMiner: explore gene co-expression in normal and pathological muscle.
Malatras, A., Michalopoulos, I., Duguez, S., Butler-Browne, G., Spuler, S. and Duddy, W.J.
BMC Medical Genomics 13
(1): 67.
11 May 2020
SorCS2 facilitates release of endostatin from astrocytes and controls post-stroke angiogenesis.
Malik, A.R., Lips, Janet, Gorniak-Walas, M., Broekaart, D.W.M., Asaro, A., Kuffner, M.T.C., Hoffmann, C.J., Kikhia, M., Dopatka, M., Boehm-Sturm, P., Mueller, S., Dirnagl, U., Aronica, E., Harms, C. and Willnow, T.E.
Glia 68
(6): 1304-1316.
June 2020
Teriflunomide preserves peripheral nerve mitochondria from oxidative stress-mediated alterations.
Malla, B., Cotten, S., Ulshoefer, R., Paul, F., Hauser, A.E., Niesner, R., Bros, H. and Infante-Duarte, C.
Therapeutic Advances in Chronic Disease 11
: 1-14.
2020
The activity of the STriatal-Enriched protein tyrosine Phosphatase (STEP) in neuronal cells is modulated by adenosine A(2A) receptor.
Mallozzi, C., Pepponi, R., Visentin, S., Chiodi, V., Lombroso, P.J., Bader, M., Popoli, P. and Domenici, M.R.
Journal of Neurochemistry 152
(3): 284-298.
February 2020
Concerted EP2 and EP4 receptor signaling stimulates autocrine prostaglandin E(2) activation in human podocytes.
Mangelsen, E., Rothe, M., Schulz, A., Kourpa, A., Panáková, D., Kreutz, R. and Bolbrinker, J.
Cells 9
(5): 1256.
19 May 2020
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto, A., Ohmura, S., Orth, M.F., Knott, M.M.L., Colombo, M.V., Arrigoni, C., Bardinet, V., Saucier, D., Wehweck, F.S., Li, J., Stein, S., Gerke, J.S., Baldauf, M.C., Musa, J., Dallmayer, M., Romero-Pérez, L., Hölting, T.L.B., Amatruda, J.F., Cossarizza, A., Henssen, A.G., Kirchner, T., Moretti, M., Cidre-Aranaz, F., Sannino, G. and Grünewald, T.G.P.
Nature Communications 11
(1): 2423.
15 May 2020
B-cell lymphoma/leukemia 10 and angiotensin II-induced kidney injury.
Markó, L., Park, J.K., Henke, N., Rong, S., Balogh, A., Klamer, S., Bartolomaeus, H., Wilck, N., Ruland, J., Forslund, S.K., Luft, F.C., Dechend, R. and Müller, D.N.
Cardiovascular Research 116
(5): 1059-1070.
1 April 2020
AP-1 imprints a reversible transcriptional programme of senescent cells.
Martínez-Zamudio, R.I., Roux, P.F., de Freitas, J.A.N.L.F., Robinson, L., Doré, G., Sun, B., Belenki, D., Milanovic, M., Herbig, U., Schmitt, C.A., Gil, J. and Bischof, O.
Nature Cell Biology 22
(7): 842-855.
July 2020
Importin α3 regulates chronic pain pathways in peripheral sensory neurons.
Marvaldi, L., Panayotis, N., Alber, S., Dagan, S.Y., Okladnikov, N., Koppel, I., Di Pizio, A., Song, D.A., Tzur, Y., Terenzio, M., Rishal, I., Gordon, D., Rother, F., Hartmann, E., Bader, M. and Fainzilber, M.
Science 369
(6505): 842-846.
14 August 2020
Enzymatic dissociation induces transcriptional and proteotype bias in brain cell populations.
Mattei, D., Ivanov, A., van Oostrum, M., Pantelyushin, S., Richetto, J., Mueller, F., Beffinger, M., Schellhammer, L., Vom Berg, J., Wollscheid, B., Beule, D., Paolicelli, R.C. and Meyer, U.
International Journal of Molecular Sciences 21
(21): 7944.
1 November 2020
EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.
Matthaeus, C., Lahmann, I., Kunz, S., Jonas, W., Melo, A.A., Lehmann, M., Larsson, E., Lundmark, R., Kern, M., Blüher, M., Olschowski, H., Kompa, J., Brügger, B., Müller, D.N., Haucke, V., Schürmann, A., Birchmeier, C. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 117
(13): 7471-7481.
31 March 2020
Latente Tuberkuloseinfektion (LTBI) bei medizinischem Personal nach Auslandseinsätzen [Latent tuberculosis infection (LTBI) among medical personnel after foreign assignments].
Meier, I., Schablon, A., Nienhaus, A. and Konigorski, S.
Pneumologie 74
(7): 429-435.
July 2020
Comparative analysis of the intracellular responses to disease-related aggregation-prone proteins.
Melnik, A., Cappelletti, V., Vaggi, F., Piazza, I., Tognetti, M., Schwarz, C., Cereghetti, G., Ahmed, M.A., Soste, M., Matlack, K., de Souza, N., Csikasz-Nagy, A. and Picotti, P.
Journal of Proteomics 225
: 103862.
15 August 2020
proGenomes2: an improved database for accurate and consistent habitat, taxonomic and functional annotations of prokaryotic genomes.
Mende, D.R., Letunic, I., Maistrenko, O.M., Schmidt, T.S.B., Milanese, A., Paoli, L., Hernández-Plaza, A., Orakov, A.N., Forslund, S.K., Sunagawa, S., Zeller, G., Huerta-Cepas, J., Coelho, L.P. and Bork, P.
Nucleic Acids Research 48
(D1): D621-D625.
8 January 2020
Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA.
Mendichovszky, I., Pullens, P., Dekkers, I., Nery, F., Bane, O., Pohlmann, A., de Boer, A., Ljimani, A., Odudu, A., Buchanan, C., Sharma, K., Laustsen, C., Harteveld, A., Golay, X., Pedrosa, I., Alsop, D., Fain, S., Caroli, A., Prasad, P., Francis, S., Sigmund, E., Fernández-Seara, M. and Sourbron, S.
Magnetic Resonance Materials in Physics Biology and Medicine 33
: 131-140.
February 2020
Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand.
Mendoza, M., Lu, D., Ballesteros, A., Blois, S.M., Abernathy, K., Feng, C., Dimitroff, C.J., Zmuda, J., Panico, M., Dell, A., Vasta, G.R., Haslam, S.M. and Dveksler, G.
Glycobiology 30
(11): 895-909.
November 2020
Value of neuropsychological tests to identify patients with depressive symptoms on the Alzheimer's disease continuum.
Menne, F., Schipke, C.G., Klostermann, A., Fuentes-Casañ, M., Freiesleben, S.D., Bauer, C. and Peters, O.
Journal of Alzheimer's Disease 78
(2): 819-826.
10 November 2020
Benchmarking single-cell RNA-sequencing protocols for cell atlas projects.
Mereu, E., Lafzi, A., Moutinho, C., Ziegenhain, C., McCarthy, D.J., Álvarez-Varela, A., Batlle, E., Sagar, Grün, D., Lau, J.K., Boutet, S.C., Sanada, C., Ooi, A., Jones, R.C., Kaihara, K., Brampton, C., Talaga, Y., Sasagawa, Y., Tanaka, K., Hayashi, T., Braeuning, C., Fischer, C., Sauer, S., Trefzer, T., Conrad, C., Adiconis, X., Nguyen, L.T., Regev, A., Levin, J.Z., Parekh, S., Janjic, A., Wange, L.E., Bagnoli, J.W., Enard, W., Gut, M., Sandberg, R., Nikaido, I., Gut, I., Stegle, O. and Heyn, H.
Nature Biotechnology 38
(6): 747-755.
June 2020
Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC.
Messerschmidt, C., Obermayer, B., Klinghammer, K., Ochsenreither, S., Treue, D., Stenzinger, A., Glimm, H., Fröhling, S., Kindler, T., Brandts, C.H., Schulze-Osthoff, K., Weichert, W., Tinhofer, I., Klauschen, F., Keilholz, U., Beule, D. and Rieke, D.T.
International Journal of Cancer 147
(8): 2293-2302.
15 October 2020
Generation of three age and gender matched pairs of human induced pluripotent stem cells derived from myoblasts (MDCi011-A, MDCi012-A, MDCi013-A) and from peripheral blood mononuclear cells (MDCi011-B, MDCi012-B, MDCi013-B) from the same donor.
Metzler, E., Telugu, N., Diecke, S., Spuler, S. and Escobar, H.
Stem Cell Research 48
: 101987.
October 2020
Generation of two human induced Pluripotent Stem Cell lines derived from myoblasts (MDCi014-A) and from peripheral blood mononuclear cells (MDCi014-B) from the same donor.
Metzler, E., Telugu, N., Diecke, S., Spuler, S. and Escobar, H.
Stem Cell Research 48
: 101998.
October 2020
HIV-1 Gag release from yeast reveals ESCRT interaction with the Gag N-terminal protein region.
Meusser, B., Purfuerst, B. and Luft, F.C.
Journal of Biological Chemistry 295
(52): 17950-17972.
25 December 2020
Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1).
Meyer, T., Jahn, N., Lindner, S., Röhner, L., Dolnik, A., Weber, D., Scheffold, A., Köpff, S., Paschka, P., Gaidzik, V.I., Heckl, D., Wiese, S., Ebert, B.L., Döhner, H., Bullinger, L., Döhner, K. and Krönke, J.
Leukemia 34
(2): 404-415.
February 2020
Blunted neural and psychological stress processing predicts future grey matter atrophy in multiple sclerosis.
Meyer-Arndt, L., Hetzer, S., Asseyer, S., Bellmann-Strobl, J., Scheel, M., Stellmann, J.Pa., Heesen, C., Engel, A.K., Brandt, A.U., Haynes, J.D., Paul, F., Gold, S.M. and Weygandt, M.
Neurobiology of Stress 13
: 100244.
November 2020
(Phospho)proteomic profiling of microsatellite unstable CRC cells reveals alterations in nuclear signaling and cholesterol metabolism caused by frameshift mutation of NMD regulator UPF3A.
Michalak, M., Katzenmaier, E.M., Roeckel, N., Woerner, S.M., Fuchs, V., Warnken, U., Yuan, Y.P., Bork, P., Neu-Yilik, G., Kulozik, A., von Knebel Doeberitz, M., Kloor, M., Kopitz, J. and Gebert, J.
International Journal of Molecular Sciences 21
(15): 5234.
23 July 2020
Spikelets in pyramidal neurons: generating mechanisms, distinguishing properties, and functional implications.
Michalikova, M., Remme, M.W.H., Schmitz, D., Schreiber, S. and Kempter, R.
Reviews in the Neurosciences 31
(1): 101-119.
January 2020
Deficiency in IκBα in the intestinal epithelium leads to spontaneous inflammation and mediates apoptosis in the gut.
Mikuda, N., Schmidt-Ullrich, R., Kärgel, E., Golusda, L., Wolf, J., Höpken, U.E., Scheidereit, C., Kühl, A.A. and Kolesnichenko, M.
Journal of Pathology 251
(2): 160-174.
June 2020
Simple workflow and comparison of media for hPSC-cardiomyocyte cryopreservation and recovery.
Miller, D.C., Genehr, C., Telugu, N.S., Kurths, S. and Diecke, S.
Current Protocols in Stem Cell Biology 55
(1): e125.
December 2020
Transient enlargement of brain ventricles during relapsing-remitting multiple sclerosis and experimental autoimmune encephalomyelitis.
Millward, J.M., Delgado, P.R., Smorodchenko, A., Boehmert, L., Periquito, J., Reimann, H.M., Prinz, C., Els, A., Scheel, M., Bellmann-Strobl, J., Waiczies, H., Wuerfel, J., Infante-Duarte, C., Chien, C., Kuchling, J., Pohlmann, A., Zipp, F., Paul, F., Niendorf, T. and Waiczies, S.
JCI Insight 5
(21): e140040.
5 November 2020
Functional and structural vascular biomarkers in women 1 year after a hypertensive disorder of pregnancy.
Moe, K., Sugulle, M., Dechend, R., Angel, K. and Staff, A.C.
Pregnancy Hypertension 21
: 23-29.
July 2020
Risk prediction of maternal cardiovascular disease one year after hypertensive pregnancy complications or gestational diabetes mellitus.
Moe, K., Sugulle, M., Dechend, R. and Staff, A.C.
European Journal of Preventive Cardiology 27
(12): 1273-1283.
1 August 2020
Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology.
Molinaro, A., Bel Lassen, P., Henricsson, M., Wu, H., Adriouch, S., Belda, E., Chakaroun, R., Nielsen, T., Bergh, P.O., Rouault, C., André, S., Marquet, F., Andreelli, F., Salem, J.E., Assmann, K., Bastard, J.P., Forslund, S., Le Chatelier, E., Falony, G., Pons, N., Prifti, E., Quinquis, B., Roume, H., Vieira-Silva, S., Hansen, T.H., Pedersen, H.K., Lewinter, C., Sønderskov, N.B., Køber, L., Vestergaard, H., Hansen, T., Zucker, J.D., Galan, P., Dumas, M.E., Raes, J., Oppert, J.M., Letunic, I., Nielsen, J., Bork, P., Ehrlich, S.D., Stumvoll, M., Pedersen, O., Aron-Wisnewsky, J., Clément, K. and Bäckhed, F.
Nature Communications 11
(1): 5881.
18 November 2020
ABVD vs BEACOPP escalated in advanced-stage Hodgkin's lymphoma: Results from a multicenter European study.
Mondello, P., Musolino, C., Dogliotti, I., Bohn, J.P., Cavallo, F., Ferrero, S., Botto, B., Cerchione, C., Nappi, D., De Lorenzo, S., Martinelli, G., Wolf, D., Schmitt, C., Loseto, G., Cuzzocrea, S., Willenbacher, W., Mian, M. and Straus, D.J.
American Journal of Hematology 95
(9): 1030-1037.
September 2020
Analysis of driver mutational hot spots in blood-derived cell-free DNA of patients with primary central nervous system lymphoma obtained before intracerebral biopsy.
Montesinos-Rongen, M., Brunn, A., Tuchscherer, A., Borchmann, P., Schorb, E., Kasenda, B., Altmüller, J., Illerhaus, G., Ruge, M.I., Maarouf, M., Büttner, R., Hansmann, M.L., Hallek, M., Prinz, M., Siebert, R. and Deckert, M.
Journal of Molecular Diagnostics 22
(10): 1300-1307.
October 2020
Circuit-specific dendritic development in the piriform cortex.
Moreno-Velasquez, L., Lo, H., Lenzi, S., Kaehne, M., Breustedt, J., Schmitz, D., Rüdiger, S. and Johenning, F.W.
eNeuro 7
(3): ENEURO.0083-20.2020.
May 2020
Renal sympathetic nerve activity regulates cardiovascular energy expenditure in rats fed high salt.
Morisawa, N., Kitada, K., Fujisawa, Y., Nakano, D., Yamazaki, D., Kobuchi, S., Li, L., Zhang, Y., Morikawa, T., Konishi, Y., Yokoo, T., Luft, F.C., Titze, J. and Nishiyama, A.
Hypertension Research 43
(6): 482-491.
June 2020
From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement.
Mostinski, Y., Heynen, G.J.J.E., López-Alberca, M.P., Paul, J., Miksche, S., Radetzki, S., Schaller, D., Shanina, E., Seyffarth, C., Kolomeets, Y., Ziebart, N., de Schryver, J., Oestreich, S., Neuenschwander, M., Roske, Y., Heinemann, U., Rademacher, C., Volkamer, A., von Kries, J.P., Birchmeier, W. and Nazaré, M.
Journal of Medicinal Chemistry 63
(23): 14780-14804.
10 December 2020
Altered fovea in AQP4-IgG-seropositive neuromyelitis optica spectrum disorders.
Motamedi, S., Oertel, F.C., Yadav, S.K., Kadas, E.M., Weise, M., Havla, J., Ringelstein, M., Aktas, O., Albrecht, P., Ruprecht, K., Bellmann-Strobl, J., Zimmermann, H.G., Paul, F. and Brandt, A.U.
Neurology Neuroimmunology & Neuroinflammation 7
(5): e805.
September 2020
A quantitative modular modeling approach reveals the effects of different A20 feedback implementations for the NF-κB signaling dynamics.
Mothes, J., Ipenberg, I., Arslan, S.Ç., Benary, U., Scheidereit, C. and Wolf, J.
Frontiers in Physiology 11
: 896.
28 July 2020
Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression.
Mucha, S., Baurecht, H., Novak, N., Rodríguez, E., Bej, S., Mayr, G., Emmert, H., Stölzl, D., Gerdes, S., Degenhardt, F., Hübenthal, M., Ellinghaus, E., Jung, E.S., Kässens, J.C., Wienbrandt, L., Lieb, W., Müller-Nurasyid, M., Hotze, M., Dand, N., Grosche, S., Marenholz, I., Arnold, A., Homuth, G., Schmidt, C.O., Wehkamp, U., Nöthen, M.M., Hoffmann, P., Paternoster, L., Standl, M., Bønnelykke, K., Ahluwalia, T.S., Bisgaard, H., Peters, A., Gieger, C., Waldenberger, M., Schulz, H., Strauch, K., Werfel, T., Lee, Y.A., Wolfien, M., Rosenstiel, P., Wolkenhauer, O., Schreiber, St., Franke, A., Weidinger, S. and Ellinghaus, D.
Journal of Allergy and Clinical Immunology 145
(4): 1208-1218.
April 2020
Comparability of compressed sensing-based gradient echo perfusion sequence SPARSE and conventional gradient echo sequence in assessment of myocardial ischemia.
Muehlberg, F., Stoetzner, A., Forman, C., Schmidt, M., Riazy, L., Dieringer, M., van der Geest, R., Schwenke, C. and Schulz-Menger, J.
European Journal of Radiology 131
: 109213.
October 2020
High-sensitivity cardiac troponin I in women with a history of early-onset preeclampsia.
Muijsers, H.E.C., Westermann, D., Birukov, A., van der Heijden, O.W.H., Drost, J.T., Kräker, K., Haase, N., Müller, D.N., Herse, F., Maas, A.H.E M, Dechend, R., Zeller, T. and Roeleveld, N.
Journal of Hypertension 38
(10): 1948-1954.
October 2020
Single-cell analysis based dissection of clonality in myelofibrosis.
Mylonas, E., Yoshida, K., Frick, M., Hoyer, K., Christen, F., Kaeda, J., Obenaus, M., Noerenberg, D., Hennch, C., Chan, W., Ochi, Y., Shiraishi, Y., Shiozawa, Y., Zenz, T., Oakes, C.C., Sawitzki, B., Schwarz, M., Bullinger, L., le Coutre, P., Rose-Zerilli, M.J.J., Ogawa, S. and Damm, F.
Nature Communications 11
(1): 73.
7 January 2020
Effect of a probiotic on blood pressure in grade 1 hypertension (HYPRO): protocol of a randomized controlled study.
Mähler, A., Wilck, N., Rauch, G., Dechend, R. and Müller, D.N.
Trials 21
(1): 1032.
29 December 2020
Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors.
Möller, J., Isbilir, A., Sungkaworn, T., Osberg, B., Karathanasis, C., Sunkara, V., Grushevskyi, E.O., Bock, A., Annibale, P., Heilemann, M., Schütte, C. and Lohse, M.J.
Nature Chemical Biology 16
(9): 946-954.
September 2020
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Müller, P.M., Rademacher, J., Bagshaw, R.D., Wortmann, C., Barth, C., van Unen, J., Alp, K.M., Giudice, G., Eccles, R.L., Heinrich, L.E., Pascual-Vargas, P., Sanchez-Castro, M., Brandenburg, L., Mbamalu, G., Tucholska, M., Spatt, L., Czajkowski, M.T., Welke, R.W., Zhang, S., Nguyen, V., Rrustemi, T., Trnka, P., Freitag, K., Larsen, B., Popp, O., Mertins, P., Gingras, A.C., Roth, F.P., Colwill, K., Bakal, C., Pertz, O., Pawson, T., Petsalaki, E. and Rocks, O.
Nature Cell Biology 22
(4): 498-511.
April 2020
Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.
Nakamura, R., Numata, T., Kasuya, G., Yokoyama, T., Nishizawa, T., Kusakizako, T., Kato, T., Hagino, T., Dohmae, N., Inoue, M., Watanabe, K., Ichijo, H., Kikkawa, M., Shirouzu, M., Jentsch, T.J., Ishitani, R., Okada, Y. and Nureki, O.
Communications Biology 3
(1): 240.
15 May 2020
Immunoglobulins G modulate endothelial function and affect insulin sensitivity in humans.
Napoli, R., Ruvolo, A., Triggianese, P., Prevete, N., Schiattarella, G.G., Nigro, C., Miele, C., Magliulo, F., Grassi, S., Pecoraro, A., Cittadini, A., Esposito, G., de Paulis, A. and Spadaro, G.
Nutrition Metabolism and Cardiovascular Diseases 30
(11): 2085-2092.
30 October 2020
NCX1 represents an ionic Na(+) sensing mechanism in macrophages.
Neubert, P., Homann, A., Wendelborn, D., Bär, A.L., Krampert, L., Trum, M., Schröder, A., Ebner, S., Weichselbaum, A., Schatz, V., Linz, P., Veelken, R., Schulte-Schrepping, J., Aschenbrenner, A.C., Quast, T., Kurts, C., Geisberger, S., Kunzelmann, K., Hammer, K., Binger, K.J., Titze, J., Müller, D.N., Kolanus, W., Schultze, J.L., Wagner, S. and Jantsch, J.
PLoS Biology 18
(6): e3000722.
22 June 2020
A novel mutation in PIGA associated with multiple congenital anomalies-hypotonia-seizure syndrome 2 (MCAHS2) in a boy with a combination of severe epilepsy and gingival hyperplasia.
Neuhofer, C.M., Funke, R., Wilken, B., Knaus, A., Altmüller, J., Nürnberg, P., Li, Y., Wollnik, B., Burfeind, P. and Pauli, S.
Molecular Syndromology 11
(1): 30-37.
February 2020
ONX 0914 lacks selectivity for the cardiac immunoproteasome in CoxsackievirusB3 myocarditis of NMRI mice and promotes virus-mediated tissue damage.
Neumaier, H.L., Harel, S., Klingel, K., Kaya, Z., Heuser, A., Kespohl, M. and Beling, A.
Cells 9
(5): 1093.
May 2020
Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy.
Ni, J., Yang, F., Huang, X.R., Meng, J., Chen, J., Bader, M., Penninger, J.M., Fung, E., Yu, X.Q. and Lan, H.Y.
Journal of Cellular and Molecular Medicine 24
(22): 13093-13103.
November 2020
Blood pressure and hypertension during pregnancy in women with polycystic ovary syndrome. Odense Child Cohort.
Nielsen, J.H., Birukov, A., Jensen, R.C., Kyhl, H.B., Jørgensen, J.S., Andersen, M.S. and Glintborg, D.
Acta Obstetricia et Gynecologica Scandinavica 99
(10): 1354-1363.
October 2020
SODAR Core: a Django-based framework for scientific data management and analysis web apps.
Nieminen, M., Stolpe, O., Schumann, F., Holtgrewe, M. and Beule, D.
Journal of Open Source Software 5
(55): 1584.
15 November 2020
Selbstberichtete Krebserkrankungen in der NAKO Gesundheitsstudie: Erfassungsmethoden und erste Ergebnisse [Self-reported cancer in the German National Cohort (NAKO Gesundheitsstudie): assessment methods and first results].
Nimptsch, K., Jaeschke, L., Chang-Claude, J., Kaaks, R., Katzke, V., Michels, K.B., Franzke, C.W., Obi, N., Becher, H., Kuß, O., Schikowski, T., Schulze, M.B., Gastell, S., Hoffmann, W., Schipf, S., Ahrens, W., Günther, K., Krist, L., Keil, T., Jöckel, K.H., Schmidt, B., Brenner, H., Holleczek, B., Fischer, B., Leitzmann, M., Lieb, W., Berger, K., Krause, G., Löffler, M., Schmidt-Pokrzywniak, A., Mikolajczyk, R., Linseisen, J., Greiser, K.H. and Pischon, T.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(4): 385-396.
April 2020
Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway.
Nitzan, N., McKenzie, S., Beed, P., English, D.F., Oldani, S., Tukker, J.J., Buzsáki, G. and Schmitz, D.
Nature Communications 11
(1): 1947.
23 April 2020
3-amino-1,2,4-triazole induces quick and strong fat loss in mice with high fat-induced metabolic syndrome.
Nunes-Souza, V., Dias-Júnior, N.M., Eleutério-Silva, M.A., Ferreira-Neves, V.P., Moura, F.A., Alenina, N., Bader, M. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2020
: 3025361.
13 April 2020
Radiofrequency applicator concepts for thermal magnetic resonance of brain tumors at 297 MHz (7.0 Tesla).
Oberacker, E., Kuehne, A., Oezerdem, C., Nadobny, J., Weihrauch, M., Beck, M., Zschaeck, S., Diesch, C., Eigentler, T.W., Waiczies, H., Ghadjar, P., Wust, P., Winter, L. and Niendorf, T.
International Journal of Hyperthermia 37
(1): 549-563.
2 June 2020
Noncanonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling.
Oberbeck, S., Schrader, A., Warner, K., Jungherz, D., Crispatzu, G., von Jan, J., Chmielewski, M., Ianevski, A., Diebner, H.H., Mayer, P., Kondo Ados, A., Wahnschaffe, L., Braun, T., Müller, T.A., Wagle, P., Bouska, A., Neumann, T., Pützer, S., Varghese, L., Pflug, N., Thelen, M., Makalowski, J., Riet, N., Göx, H.J.M, Rappl, G., Altmüller, J., Kotrová, M., Persigehl, T., Hopfinger, G., Hansmann, M.L., Schlößer, H., Stilgenbauer, S., Dürig, J., Mougiakakos, D., von Bergwelt-Baildon, M., Roeder, I., Hartmann, S., Hallek, M., Moriggl, R., Brüggemann, M., Aittokallio, T., Iqbal, J., Newrzela, S., Abken, H. and Herling, M.
Blood 136
(24): 2786-2802.
10 December 2020
SCelVis: exploratory single cell data analysis on the desktop and in the cloud.
Obermayer, B., Holtgrewe, M., Nieminen, M., Messerschmidt, C. and Beule, D.
PeerJ 8
: e8607.
19 February 2020
Soluble (pro)renin receptor in elderly chronic heart failure patients.
Obradovic, D., Loncar, G., Radenovic, S., Tahirovic, E., Heidecke, H., Schulze-Forster, K., Muller, D., Busjahn, A., Buttner, P., Veskovic, J., Zdravkovic, M., Li, H., Li, S., Savkovic, V., Pieske, B., Dungen, H.D. and Dechend, R.
Frontiers in Bioscience-Landmark 25
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Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial.
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May 2020
Towards a more reliable identification of isomeric metabolites using pattern guided retention validation.
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12 November 2020
High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma.
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10 March 2020
Instrumental assessment of stepping in place captures clinically relevant motor symptoms of Parkinson's disease.
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1 October 2020
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An in vivo strategy for knockdown of circular RNAs.
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Pairwise stimulations of pathogen-sensing pathways predict immune responses to multi-adjuvant combinations.
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The sensory coding of warm perception.
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Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia.
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April 2020
TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.
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3 September 2020
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14 June 2020
Multiplexed quantification of four neuroblastoma DNA targets in a single droplet digital PCR reaction.
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November 2020
The genomic and clinical landscape of fetal akinesia.
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March 2020
Kinetic analysis of the early signaling steps of the human chemokine receptor CXCR4.
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August 2020
Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis.
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A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes.
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Targeting claudin-overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin.
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Effects of diets high in animal or plant protein on oxidative stress in individuals with type 2 diabetes: a randomized clinical trial.
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Using gradient boosting with stability selection on health insurance claims data to identify disease trajectories in chronic obstructive pulmonary disease.
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A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation.
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Association of germline variant status with therapy response in high-risk early-stage breast cancer: a secondary analysis of the GeparOcto randomized clinical trial.
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May 2020
Familial recurrent myocarditis triggered by exercise in patients with a truncating variant of the desmoplakin gene.
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18 May 2020
A recurrent gain-of-function mutation in CLCN6, encoding the ClC-6 Cl-/H+-exchanger, causes early-onset neurodegeneration.
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3 December 2020
Recurrent inversion toggling and great ape genome evolution.
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First-line treatment with R-CHOP or rituximab-bendamustine in patients with follicular lymphoma grade 3A - results of a retrospective analysis.
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A statistical view on calcium oscillations.
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Tracing tumorigenesis in a solid tumor model at single-cell resolution.
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20 February 2020
Splicing-accessible coding 3'UTRs control protein stability and interaction networks.
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29 July 2020
Better prognosis of gastric cancer patients with high levels of tumor infiltrating lymphocytes is counteracted by PD-1 expression.
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Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.
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3 November 2020
Paroxysmal tonic upgaze: a heterogeneous clinical condition responsive to carbonic anhydrase inhibition.
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March 2020
Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells.
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24 September 2020
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19 November 2020
Functional annotation of human long noncoding RNAs via molecular phenotyping.
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July 2020
B(1) inhomogeneity correction of RARE MRI with transceive surface radiofrequency probes.
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November 2020
Non-ionic PEG-oligoglycerol dendron conjugated nano-carriers for dermal drug delivery.
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Telmisartan prevents development of obesity and normalizes hypothalamic lipid droplets.
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Journal of Endocrinology 244
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January 2020
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features.
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Nature Communications 11
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6 March 2020
The mole genome reveals regulatory rearrangements associated with adaptive intersexuality.
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Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1.
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17 December 2020
Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome.
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Nature Communications 11
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14 April 2020
Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology.
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September 2020
Longitudinal optic neuritis-unrelated visual evoked potential changes in NMO spectrum disorders.
Ringelstein, M., Harmel, J., Zimmermann, H., Brandt, A.U., Paul, F., Haarmann, A., Buttmann, M., Hümmert, M.W., Trebst, C., Schroeder, C., Ayzenberg, I., Kleiter, I., Hellwig, K., Havla, J., Kümpfel, T., Jarius, S., Wildemann, B., Rommer, P., Weber, M.S., Pellkofer, H., Röpke, L., Geis, C., Retzlaff, N., Zettl, U., Deppe, M., Klotz, L., Young, K., Stellmann, J.P., Kaste, M., Kermer, P., Marouf, W., Lauda, F., Tumani, H., Graf, J., Klistorner, A., Hartung, H.P., Aktas, O. and Albrecht, P.
Neurology 94
(4): e407-e418.
28 January 2020
Phosphorylation of RAB7 by TBK1/IKKε regulates innate immune signaling in triple negative breast cancer.
Ritter, J.L., Zhu, Z., Thai, T.C., Mahadevan, N.R., Mertins, P., Knelson, E.H., Piel, B.P., Han, S., Jaffe, J.D., Carr, S.A., Barbie, D.A. and Barbie, T.U.
Cancer Research 80
(1): 44-56.
January 2020
Angiotensin-(1-7) prevents lipopolysaccharide-induced autophagy via the Mas receptor in skeletal muscle.
Rivera, J.C., Abrigo, J., Tacchi, F., Simon, F., Brandan, E., Santos, R.A., Bader, M., Chiong, M. and Cabello-Verrugio, C.
International Journal of Molecular Sciences 21
(24): 9344.
8 December 2020
Instability of circular RNAs in clinical tissue samples impairs their reliable expression analysis using RT-qPCR: from the myth of their advantage as biomarkers to reality.
Rochow, H., Franz, A., Jung, M., Weickmann, S., Ralla, B., Kilic, E., Stephan, C., Fendler, A. and Jung, K.
Theranostics 10
(20): 9268-9279.
23 July 2020
Circular RNAs and their linear transcripts as diagnostic and prognostic tissue biomarkers in prostate cancer after prostatectomy in combination with clinicopathological factors.
Rochow, H., Jung, M., Weickmann, S., Ralla, B., Stephan, C., Elezkurtaj, S., Kilic, E., Zhao, Z., Jung, K., Fendler, A. and Franz, A.
International Journal of Molecular Sciences 21
(21): E7812.
22 October 2020
Neuroinflammatory alterations in trait anxiety: modulatory effects of minocycline.
Rooney, S., Sah, A., Unger, M.S., Kharitonova, M., Sartori, S.B., Schwarzer, C., Aigner, L., Kettenmann, H., Wolf, S.A. and Singewald, N.
Translational Psychiatry 10
(1): 256.
30 July 2020
Comparison of RNA isolation procedures for analysis of adult murine brain and spinal cord astrocytes.
Rosiewicz, K.S., Crowley, T., Saher, G., Kerkering, J., Alisch, M. and Siffrin, V.
Journal of Neuroscience Methods 333
: 108545.
1 March 2020
Targeting CD33 in chemoresistant AML patient-derived xenografts by CAR-CIK cells modified with an improved SB transposon system.
Rotiroti, M.C., Buracchi, C., Arcangeli, S., Galimberti, S., Valsecchi, M.G., Perriello, V.M., Rasko, T., Alberti, G., Magnani, C.F., Cappuzzello, C., Lundberg, F., Pande, A., Dastoli, G., Introna, M., Serafini, M., Biagi, E., Izsvák, Z., Biondi, A. and Tettamanti, S.
Molecular Therapy 28
(9): 1974-1986.
2 September 2020
Diffusive dynamics and jamming in ensembles of robots with variable friction.
Rozenblit, A.D., Porvatov, V.A., Petrova, D.A., Khakhalin, I.S., Kotlyar, K.P., Gritsenko, G.Y., Evreiskaya, A.A., Lebedeva, M.F., Kretov, E.I., Filonov, D.S., Souslov, A. and Olekhno, N.A.
Journal of Physics: Conference Series 1695
(1): 012201.
28 December 2020
Quantification of mRNA expression using single-molecule nanopore sensing.
Rozevsky, Y., Gilboa, T., van Kooten, X.F., Kobelt, D., Huttner, D., Stein, U. and Meller, A.
ACS Nano 14
(10): 13964-13974.
27 October 2020
Deconstructing sarcomeric structure-function relations in titin-BioID knock-in mice.
Rudolph, F., Fink, C., Hüttemeister, J., Kirchner, M., Radke, M.H., Lopez Carballo, J., Wagner, E., Kohl, T., Lehnart, S.E., Mertins, P. and Gotthardt, M.
Nature Communications 11
(1): 3133.
19 June 2020
Mapping the transglycosylation relevant sites of cold-adapted β-d-galactosidase from arthrobacter sp. 32cB.
Rutkiewicz, M., Wanarska, M. and Bujacz, A.
International Journal of Molecular Sciences 21
(15): 5354.
28 July 2020
Direct lineage reprogramming: harnessing cell plasticity between liver and pancreas.
Ruzittu, S., Willnow, D. and Spagnoli, F.M.
Cold Spring Harbor Perspectives in Biology 12
(7): a035626.
July 2020
Dysphagia affecting quality of life in cerebellar ataxia - a large survey.
Rönnefarth, M., Hanisch, N., Brandt, A.U., Mähler, A., Endres, M., Paul, F. and Doss, S.
Cerebellum 19
(3): 437-445.
June 2020
Tissue sodium stores in peritoneal dialysis and hemodialysis patients determined by 23-sodium magnetic resonance imaging.
Sahinoz, M., Tintara, S., Deger, S.M., Alsouqi, A., Crescenzi, R.L., Mambungu, C., Vincz, A., Mason, O., Prigmore, H.L., Guide, A., Stewart, T.G., Harrison, D., Luft, F.C., Titze, J. and Alp Ikizler, T.
Nephrology Dialysis Transplantation
: gfaa350.
22 December 2020
Intestinal expression of toll-like receptor gene changes early after gastric bypass surgery and association with type 2 diabetes remission.
Sala, P., Torrinhas, R.S.M.M., Fonseca, D.C., Machado, N.M., Singer, J., Singer, P., Ravacci, G.R., Belarmino, G., Ferreira, B.A.M., Marques, M., Ishida, R.K., Guarda, I.F.M.S., de Moura, E.G.H., Sakai, P., Santo, M.A., Sunaga, D.Y., Heymsfield, S.B., Bezerra, D.P.D.S., Corrêa-Giannella, M.L. and Waitzberg, D.L.
Nutrition 79-80
: 110885.
November 2020
Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function.
Salzer, B., Schueller, C.M., Zajc, C.U., Peters, T., Schoeber, M.A., Kovacic, B., Buri, M.C., Lobner, E., Dushek, O., Huppa, J.B., Obinger, C., Putz, E.M., Holter, W., Traxlmayr, M.W. and Lehner, M.
Nature Communications 11
(1): 4166.
20 August 2020
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity.
Salzer, E., Zoghi, S., Kiss, M.G., Kage, F., Rashkova, C., Stahnke, S., Haimel, M., Platzer, R., Caldera, M., Ardy, R.C., Hoeger, B., Block, J., Medgyesi, D., Sin, C., Shahkarami, S., Kain, R., Ziaee, V., Hammerl, P., Bock, C., Menche, J., Dupré, L., Huppa, J.B., Sixt, M., Lomakin, A., Rottner, K., Binder, C.J., Stradal, T.E.B., Rezaei, N. and Boztug, K.
Science Immunology 5
(49): eabc3979.
10 July 2020
Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1).
Samir, M., Vidal, R.O., Abdallah, F., Capece, V., Seehusen, F., Geffers, R., Hussein, A., Ali, A.A.H., Bonn, S. and Pessler, F.
RNA Biology 17
(1): 112-124.
January 2020
Subnanometer-resolution structure determination in situ by hybrid subtomogram averaging - single particle cryo-EM.
Sanchez, R.M., Zhang, Y., Chen, W., Dietrich, L. and Kudryashev, M.
Nature Communications 11
(1): 3709.
24 July 2020
Single-cell analysis of structural variations and complex rearrangements with tri-channel processing.
Sanders, A.D., Meiers, S., Ghareghani, M., Porubsky, D., Jeong, H., van Vliet, M.A.C.C., Rausch, T., Richter-Pechańska, P., Kunz, J.B., Jenni, S., Bolognini, D., Longo, G.M.C., Raeder, B., Kinanen, V., Zimmermann, J., Benes, V., Schrappe, M., Mardin, B.R., Kulozik, A.E., Bornhauser, B., Bourquin, J.P., Marschall, T. and Korbel, J.O.
Nature Biotechnology 38
(3): 343-354.
March 2020
Development of high-specificity fluorescent probes to enable cannabinoid type 2 receptor studies in living cells.
Sarott, R.C., Westphal, M., Pfaff, P., Korn, C., Sykes, D.A., Gazzi, T., Brennecke, B., Atz, K., Weise, M., Mostinski, Y., Hompluem, P., Koers, E., Miljus, T., Roth, N.J., Asmelash, H., Vong, M.C., Piovesan, J., Guba, W., Rufer, A., Kusznir, E.A., Huber, S., Raposo, C., Zirwes, E.A., Osterwald, A., Pavlovic, A., Moes, S., Beck, J., Benito-Cuesta, I., Grande, T., Ruiz de Martin, S., Yeliseev, A.A., Drawnel, F., Widmer, G., Holzer, D., van der Wel, T., Mandhair, H., Yuan, C.Y., Drobyski, W., Saroz, Y., Grimsey, N.L., Honer, M., Fingerle, J., Gawrisch, K., Romero, J., Hillard, C., Varga, Z., van der Stelt, M., Pacher, P., Gertsch, J., McCormick, P., Ullmer, C., Oddi, S., Maccarrone, M., Veprintsev, D., Nazaré, M., Grether, U. and Carreira, E.M.
Journal of the American Chemical Society 142
(40): 16953-16964.
7 October 2020
An international standardized magnetic resonance imaging protocol for diagnosis and follow-up of patients with multiple sclerosis.
Saslow, L., Li, D.K.B., Halper, J., Banwell, B., Barkhof, F., Barlow, L., Costello, K., Damiri, P., Dunn, J., Giri, S., Maes, M., Morrow, S.A., Newsome, S.D., Oh, J., Paul, F., Quarterman, P., Reich, D.S., Shewchuk, J.R., Shinohara, R.T., Van Hecke, W., van de Ven, K., Wallin, M.T., Wolinsky, J.S. and Traboulsee, A.
International Journal of MS Care 22
(5): 226-232.
27 October 2020
Exome sequencing in 38 patients with intracranial aneurysms and subarachnoid hemorrhage.
Sauvigny, T., Alawi, M., Krause, L., Renner, S., Spohn, M., Busch, A., Kolbe, V., Altmüller, J., Löscher, B.S., Franke, A., Brockmann, C., Lieb, W., Westphal, M., Schmidt, N.O., Regelsberger, J. and Rosenberger, G.
Journal of Neurology 267
(9): 2533-2545.
September 2020
The absence of serotonin in the brain alters acute stress responsiveness by interfering with the genomic function of the glucocorticoid receptors.
Sbrini, G., Brivio, P., Peeva, P.M., Todiras, M., Bader, M., Alenina, N. and Calabrese, F.
Frontiers in Cellular Neuroscience 14
: 128.
1 June 2020
Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS).
Scheer, M., Blank, B., Bauer, S., Vokuhl, C., Stegmaier, S., Feuchtgruber, S., Henssen, A., Sparber-Sauer, M., Eggert, A., Handgretinger, R., Pekrun, A., Rossig, C., Rutkowski, S., Schlegel, P.G., Schrappe, M., Simon, T., Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Jahnukainen, K., Fuchs, J., Bielack, S.S., Koscielniak, E. and Klingebiel, T.
Journal of Cancer Research and Clinical Oncology 146
(4): 953-960.
April 2020
Cold-induced urticarial autoinflammatory syndrome related to factor XII activation.
Scheffel, J., Mahnke, N.A., Hofman, Z.L.M., Maat, S.d., Wu, J., Bonnekoh, H., Pengelly, R.J., Ennis, S., Holloway, J.W., Kirchner, M., Mertins, P., Church, M.K., Maurer, M., Maas, C. and Krause, K.
Nature Communications 11
(1): 179.
10 January 2020
A connectome and analysis of the adult Drosophila central brain.
Scheffer, L.K., Xu, C.S., Januszewski, M., Lu, Z., Takemura, S.Y., Hayworth, K.J., Huang, G.B., Shinomiya, K., Maitlin-Shepard, J., Berg, S., Clements, J., Hubbard, P.M., Katz, W.T., Umayam, L., Zhao, T., Ackerman, D., Blakely, T., Bogovic, J., Dolafi, T., Kainmueller, D., Kawase, T., Khairy, K.A., Leavitt, L., Li, P.H., Lindsey, L., Neubarth, N., Olbris, D.J., Otsuna, H., Trautman, E.T., Ito, M., Bates, A.S., Goldammer, J., Wolff, T., Svirskas, R., Schlegel, P., Neace, E.R., Knecht, C.J., Alvarado, C.X., Bailey, D.A., Ballinger, S., Borycz, J.A., Canino, B.S., Cheatham, N., Cook, M., Dreher, M., Duclos, O., Eubanks, B., Fairbanks, K., Finley, S., Forknall, N., Francis, A., Hopkins, G.P., Joyce, E.M., Kim, S.J., Kirk, N.A., Kovalyak, J., Lauchie, S.A., Lohff, A., Maldonado, C., Manley, E.A., McLin, S., Mooney, C., Ndama, M., Ogundeyi, O., Okeoma, N., Ordish, C., Padilla, N., Patrick, C., Paterson, T., Phillips, E.E., Phillips, E.M., Rampally, N., Ribeiro, C., Robertson, M.K., Rymer, J.T., Ryan, S.M., Sammons, M., Scott, A.K., Scott, A.L., Shinomiya, A., Smith, C., Smith, K., Smith, N.L., Sobeski, M.A., Suleiman, A., Swift, J., Takemura, S., Talebi, I., Tarnogorska, D., Tenshaw, E., Tokhi, T., Walsh, J.J., Yang, T., Horne, J.A., Li, F., Parekh, R., Rivlin, P.K., Jayaraman, V., Costa, M., Jefferis, G.S.X.E., Ito, K., Saalfeld, S., George, R., Meinertzhagen, I.A., Rubin, G.M., Hess, H.F., Jain, V. and Plaza, S.M.
eLife 9
: e57443.
7 September 2020
Distinctive patterns of inflammation across the heart failure syndrome.
Schiattarella, G.G., Sequeira, V. and Ameri, P.
Heart Failure Reviews 26
: 1333–1344.
November 2020
Development of a conformational histamine H(3) receptor biosensor for the synchronous screening of agonists and inverse agonists.
Schihada, H., Ma, X., Zabel, U., Vischer, H.F., Schulte, G., Leurs, R., Pockes, S. and Lohse, M.J.
ACS Sensors 5
(6): 1734-1742.
26 June 2020
Blutdruckmessung in der NAKO - methodische Unterschiede, Blutdruckverteilung und Bekanntheit der Hypertonie im Vergleich zu anderen bevölkerungsbezogenen Studien in Deutschland [Blood pressure measurement in the NAKO German National Cohort (GNC) - differences in methods, distribution of blood pressure values, and awareness of hypertension compared to other population-based studies in Germany].
Schikowski, T., Wigmann, C., Fuks, K.B., Schipf, S., Heier, M., Neuhauser, H., Sarganas, G., Ahrens, W., Becher, H., Berger, K., Brenner, H., Castell, S., Damms-Machado, A., Dörr, M., Ebert, N., Efremov, L., Emmel, C., Felix, S.B., Fischer, B., Franzke, C.W., Gastell, S., Günther, K., Haerting, J., Ittermann, T., Jaeschke, L., Jagodzinski, A., Jöckel, K.H., Kaaks, R., Kalinowski, S., Keil, T., Kemmling, Y., Kluttig, A., Krist, L., Kuss, O., Legath, N., Leitzmann, M., Lieb, W., Löffler, M., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Moebus, S., Nuding, S., Peters, A., Pischon, T., Rückert-Eheberg, I.M., Schöttker, B., Schmidt, B., Schmidt, C.O., Schulze, M.B., Stang, A., Thiele, I., Thierry, S., Thorand, B., Völzke, H., Waniek, S., Werdan, K., Wirkner, K. and Greiser, K.H.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(4): 452-464.
April 2020
Natural compound library screening identifies new molecules for the treatment of cardiac fibrosis and diastolic dysfunction.
Schimmel, K., Jung, M., Foinquinos, A., San José, G., Beaumont, J., Bock, K., Grote-Levi, L., Xiao, K., Bär, C., Pfanne, A., Just, A., Zimmer, K., Ngoy, S., López, B., Ravassa, S., Samolovac, S., Janssen-Peters, H., Remke, J., Scherf, K., Dangwal, S., Piccoli, M.T., Kleemiss, F., Kreutzer, F.P., Kenneweg, F., Leonardy, J., Hobuß, L., Santer, L., Do, Q.T., Geffers, R., Braesen, J.H., Schmitz, J., Brandenberger, C., Müller, D.N., Wilck, N., Kaever, V., Bähre, H., Batkai, S., Fiedler, J., Alexander, K.M., Wertheim, B.M., Fisch, S., Liao, R., Diez, J., González, A. and Thum, T.
Circulation 141
(9): 751-767.
3 March 2020
Die Basiserhebung der NAKO Gesundheitsstudie: Teilnahme an den Untersuchungsmodulen, Qualitätssicherung und Nutzung von Sekundärdaten [The baseline assessment of the German National Cohort (NAKO Gesundheitsstudie): participation in the examination modules, quality assurance, and the use of secondary data].
Schipf, S., Schöne, G., Schmidt, B., Günther, K., Stübs, G., Greiser, K.H., Bamberg, F., Meinke-Franze, C., Becher, H., Berger, K., Brenner, H., Castell, S., Damms-Machado, A., Fischer, B., Franzke, C.W., Fricke, J., Gastell, S., Günther, M., Hoffmann, W., Holleczek, B., Jaeschke, L., Jagodzinski, A., Jöckel, K.H., Kaaks, R., Kauczor, H.U., Kemmling, Y., Kluttig, A., Krist, L., Kurth, B., Kuß, O., Legath, N., Leitzmann, M., Lieb, W., Linseisen, J., Löffler, M., Michels, K.B., Mikolajczyk, R., Pigeot, I., Mueller, U., Peters, A., Rach, S., Schikowski, T., Schulze, M.B., Stallmann, C., Stang, A., Swart, E., Waniek, S., Wirkner, K., Völzke, H., Pischon, T. and Ahrens, W.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(3): 254-266.
March 2020
H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.
Schleich, K., Kase, J., Dörr, J.R., Trescher, S., Bhattacharya, A., Yu, Y., Wailes, E.M., Fan, D.N.Y., Lohneis, P., Milanovic, M., Lau, A., Lenze, D., Hummel, M., Chapuy, B., Leser, U., Reimann, M., Lee, S. and Schmitt, C.A.
Nature Communications 11
(1): 3651.
20 July 2020
Häufigkeiten muskuloskelettaler Symptome und Erkrankungen in der bevölkerungsbezogenen NAKO Gesundheitsstudie [Frequencies of musculoskeletal symptoms and disorders in the population-based German National Cohort (GNC)].
Schmidt, C.O., Günther, K.P., Goronzy, J., Albrecht, K., Chenot, J.F., Callhoff, J., Richter, A., Kasch, R., Ahrens, W., Becher, H., Berger, K., Brenner, H., Fischer, B., Franzke, C.W., Hoffmann, W., Holleczek, B., Jaeschke, L., Jenning, C., Jöckel, K.H., Kaaks, R., Keil, T., Kluttig, A., Krause, G., Kuß, O., Leitzmann, M., Lieb, W., Linseisen, J., Löffler, M., Meinke-Franze, C., Meisinger, C., Michels, K.B., Mikolajczyk, R., Obi, N., Peters, A., Pischon, T., Schikowski, T., Schipf, S., Specker, C., Völzke, H., Wirkner, K., Zink, A. and Sander, O.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(4): 415-425.
April 2020
Differences in advanced magnetic resonance imaging in MOG-IgG and AQP4-IgG seropositive neuromyelitis optica spectrum disorders: a comparative study.
Schmidt, F.A., Chien, C., Kuchling, J., Bellmann-Strobl, J., Ruprecht, K., Siebert, N., Asseyer, S., Jarius, S., Brandt, A.U., Scheel, M. and Paul, F.
Frontiers in Neurology 11
: 499910.
30 September 2020
B-cell-specific Myd88 L252P expression causes a premalignant gammopathy resembling IgM MGUS.
Schmidt, K., Sack, U., Graf, R., Winkler, W., Popp, O., Mertins, P., Sommermann, T., Kocks, C. and Rajewsky, K.
Frontiers in Immunology 11
: 602868.
1 December 2020
The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Scholz, F., Grau, M., Menzel, L., Graband, A., Zapukhlyak, M., Leutz, A., Janz, M., Lenz, G., Rehm, A. and Höpken, U.E.
Proceedings of the National Academy of Sciences of the United States of America 117
(42): 26328-26339.
20 October 2020
Neutrophil gelatinase-associated lipocalin protects from ANCA-induced GN by inhibiting T(H)17 immunity.
Schreiber, A., Rousselle, A., Klocke, J., Bachmann, S., Popovic, S., Bontscho, J., Schmidt-Ott, K.M., Siffrin, V., Jerke, U., Ashraf, M.I., Panzer, U. and Kettritz, R.
Journal of the American Society of Nephrology 31
(7): 1569-1584.
July 2020
Evidence of pathogenicity for the leaky splice variant c.1066-6T>G in ATM.
Schröder, S., Wieland, B., Ohlenbusch, A., Yigit, G., Altmüller, J., Boltshauser, E., Dörk, T. and Brockmann, K.
American Journal of Medical Genetics A 182
(12): 2971-2975.
December 2020
Severe COVID-19 is marked by a dysregulated myeloid cell compartment.
Schulte-Schrepping, J., Reusch, N., Paclik, D., Baßler, K., Schlickeiser, S., Zhang, B., Krämer, B., Krammer, T., Brumhard, S., Bonaguro, L., De Domenico, E., Wendisch, Da., Grasshoff, M., Kapellos, T.S., Beckstette, M., Pecht, T., Saglam, A., Dietrich, O., Mei, H.E., Schulz, A.R., Conrad, C., Kunkel, D., Vafadarnejad, E., Xu, C.J., Horne, A., Herbert, M., Drews, A., Thibeault, C., Pfeiffer, M., Hippenstiel, S., Hocke, A., Müller-Redetzky, H., Heim, K.M., Machleidt, F., Uhrig, A., Bosquillon de Jarcy, L., Jürgens, L., Stegemann, M., Glösenkamp, C.R., Volk, H.D., Goffinet, C., Landthaler, M., Wyler, E., Georg, P., Schneider, M., Dang-Heine, C., Neuwinger, N., Kappert, K., Tauber, R., Corman, V., Raabe, J., Kaiser, K.M., Vinh, M.T., Rieke, G., Meisel, C., Ulas, T., Becker, M., Geffers, R., Witzenrath, M., Drosten, C., Suttorp, N., von Kalle, C., Kurth, F., Händler, K., Schultze, J.L., Aschenbrenner, A.C., Li, Y., Nattermann, J., Sawitzki, B., Saliba, A.E. and Sander, L.E.
Cell 182
(6): 1419-1440.
17 September 2020
Standardized image interpretation and post-processing in cardiovascular magnetic resonance - 2020 update : Society for Cardiovascular Magnetic Resonance (SCMR): Board of Trustees Task Force on Standardized Post-Processing.
Schulz-Menger, J., Bluemke, D.A., Bremerich, J., Flamm, S.D., Fogel, M.A., Friedrich, M.G., Kim, R.J., von Knobelsdorff-Brenkenhoff, F., Kramer, C.M., Pennell, D.J., Plein, S. and Nagel, E.
Journal of Cardiovascular Magnetic Resonance 22
(1): 19.
12 March 2020
The transcriptome dynamics of single cells during the cell cycle.
Schwabe, D., Formichetti, S., Junker, J.P., Falcke, M. and Rajewsky, N.
Molecular Systems Biology 16
(11): e9946.
1 November 2020
Spatio-temporal bone remodeling after hematopoietic stem cell transplantation.
Schwarz, C.S., Bucher, C.H., Schlundt, C., Mertlitz, S., Riesner, K., Kalupa, M., Verlaat, L., Schmidt-Bleek, O., Sass, R.A., Schmidt-Bleek, K., Duda, G.N., Penack, O. and Na, I.K.
International Journal of Molecular Sciences 22
(1): 267.
29 December 2020
67-Jährige Patientin mit Sinusitis, Hautvaskulitis und Nierenversagen [67-year-old female patient with sinusitis, skin vasculitis and kidney failure].
Seelow, E., Rudolph, B., Schreiber, A. and Kettritz, R.
Nephrologe 15
(6): 363-365.
November 2020
Generation and characterization of a mitotane-resistant adrenocortical cell line.
Seidel, E., Walenda, G., Messerschmidt, C., Obermayer, B., Peitzsch, M., Wallace, P., Bahethi, R., Yoo, T., Choi, M., Schrade, P., Bachmann, S., Liebisch, G., Eisenhofer, G., Beule, D. and Scholl, U.
Endocrine Connections 9
(2): 122-134.
February 2020
Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity.
Seo, J.A., Kang, M.C., Yang, W.M., Hwang, W.M., Kim, S.S., Hong, S.H., Heo, J.I., Vijyakumar, A., Pereira de Moura, L., Uner, A., Huang, H., Lee, S.H., Lima, I.S., Park, K.S., Kim, M.S., Dagon, Y., Willnow, T.E., Aroda, V., Ciaraldi, T.P., Henry, R.R. and Kim, Y.B.
Nature Communications 11
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Ang II (angiotensin II) conversion to angiotensin-(1-7) in the circulation is POP (prolyloligopeptidase)-dependent and ACE2 (angiotensin-converting enzyme 2)-independent.
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January 2020
Collagen organization within the cartilage of TRPV4(-/-) mice studied with two-photon microscopy and polarized second harmonic generation.
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May 2020
The effects of common structural variants on 3D chromatin structure.
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BMC Genomics 21
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30 January 2020
Tumour-derived CSF2/granulocyte macrophage colony stimulating factor controls myeloid cell accumulation and progression of gliomas.
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British Journal of Cancer 123
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4 August 2020
The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay.
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Nucleic Acids Research 48
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18 March 2020
Near real-time bedside detection of spinal cord ischaemia during aortic repair by microdialysis of the cerebrospinal fluid.
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European Journal of Cardio-Thoracic Surgery 58
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September 2020
Limited utility of qPCR-based detection of tumor-specific circulating mRNAs in whole blood from clear cell renal cell carcinoma patients.
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BMC Urology 20
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4 February 2020
Human endogenous retrovirus K rec forms a regulatory loop with MITF that opposes the progression of melanoma to an invasive stage.
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Viruses 12
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13 November 2020
Afadin signaling at the spinal neuroepithelium regulates central canal formation and gait selection.
Skarlatou, S., Hérent, C., Toscano, E., Mendes, C.S., Bouvier, J. and Zampieri, N.
Cell Reports 31
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9 June 2020
Bacteriophages: emerging applications in medicine, food, and biotechnology.
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PHAGE 1
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16 June 2020
Using unlabeled data to discover bivariate causality with deep restricted Boltzmann machines.
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IEEE/ACM Transactions on Computational Biology and Bioinformatics 17
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January 2020
Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.
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Proceedings of the National Academy of Sciences of the United States of America 117
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23 June 2020
Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders (CROCTINO).
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BMJ Open 10
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29 October 2020
Attenuated epigenetic suppression of muscle stem cell necroptosis is required for efficient regeneration of dystrophic muscles.
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Cell Reports 31
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19 May 2020
NMR quality control of fragment libraries for screening.
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Journal of Biomolecular NMR 74
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November 2020
Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing.
Stangl, C., de Blank, S., Renkens, I., Westera, L., Verbeek, T., Valle-Inclan, J.E., Chamorro González, R., Henssen, A.G., van Roosmalen, M.J., Stam, R.W., Voest, E.E., Kloosterman, W.P., van Haaften, G. and Monroe, G.R.
Nature Communications 11
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5 June 2020
Performance of compressed sensing for fluorine-19 magnetic resonance imaging at low signal-to-noise ratio conditions.
Starke, L., Pohlmann, A., Prinz, C., Niendorf, T. and Waiczies, S.
Magnetic Resonance in Medicine 84
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August 2020
HCoV- and SARS-CoV-2 cross-reactive T cells in CVID patients.
Steiner, S., Sotzny, F., Bauer, S., Na, I.K., Schmueck-Henneresse, M., Corman, V.M., Schwarz, T., Drosten, C., Wendering, D.J., Behrends, U., Volk, H.D., Scheibenbogen, C. and Hanitsch, L.G.
Frontiers in Immunology 11
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23 December 2020
Antibody signatures in patients with histopathologically defined multiple sclerosis patterns.
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Acta Neuropathologica 139
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March 2020
Combination therapy with Olaratumab/doxorubicin in advanced or metastatic soft tissue sarcoma -a single-Centre experience.
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BMC Cancer 20
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29 January 2020
Lipid mediator profiles predict response to therapy with an oral frankincense extract in relapsing-remitting multiple sclerosis.
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Scientific Reports 10
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29 May 2020
Phosphatidylinositol 4-kinase β mutations cause nonsyndromic sensorineural deafness and inner ear malformation.
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20 October 2020
A highly conserved circular RNA is required to keep neural cells in a progenitor state in the mammalian brain.
Suenkel, C., Cavalli, D., Massalini, S., Calegari, F. and Rajewsky, N.
Cell Reports 30
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18 February 2020
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes.
Sungnak, W., Huang, N., Bécavin, C., Berg, M., Queen, R., Litvinukova, M., Talavera-López, C., Maatz, H., Reichart, D., Sampaziotis, F., Worlock, K.B., Yoshida, M. and Barnes, J.L.
Nature Medicine 26
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May 2020
Human liver memory CD8(+) T cells use autophagy for tissue residence.
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Cell Reports 30
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21 January 2020
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.
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PLoS Genetics 16
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28 December 2020
N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation.
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Journal of Biological Chemistry 295
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18 December 2020
Towards a deeper annotation of human lncRNAs.
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April 2020
Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data.
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November 2020
Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.
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Haematologica 105
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October 2020
Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.
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Blood 135
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25 June 2020
Age-related shift in LTD is dependent on neuronal adenosine A(2A) receptors interplay with mGluR5 and NMDA receptors.
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Molecular Psychiatry 25
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August 2020
ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope.
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European Journal of Immunology 50
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February 2020
Cellular importin-α3 expression dynamics in the lung regulate antiviral response pathways against influenza a virus infection.
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Cell Reports 31
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21 April 2020
Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.
Thole, T.M., Toedling, J., Sprüssel, A., Pfeil, S., Savelyeva, L., Capper, D., Messerschmidt, C., Beule, D., Groeneveld-Krentz, S., Eckert, C., Gambara, G., Henssen, A.G., Finkler, S., Schulte, J.H., Sieber, A., Bluethgen, N., Regenbrecht, C.R.A., Künkele, A., Lodrini, M., Eggert, A. and Deubzer, H.E.
International Journal of Cancer 146
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15 February 2020
Phosphosite analysis of the cytomegaloviral mRNA export factor pUL69 reveals serines with critical importance for recruitment of cellular proteins Pin1 and UAP56/URH49.
Thomas, M., Müller, R., Horn, G., Bogdanow, B., Imami, K., Milbradt, J., Steingruber, M., Marschall, M., Schilling, E.M., Fossen, T. and Stamminger, T.
Journal of Virology 94
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31 March 2020
Small-molecule dual PLK1 and BRD4 inhibitors are active against preclinical models of pediatric solid tumors.
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Translational Oncology 13
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February 2020
N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma.
Tjaden, B., Baum, K., Marquardt, V., Simon, M., Trajkovic-Arsic, M., Kouril, T., Siebers, B., Lisec, J., Siveke, J.T., Schulte, J.H., Benary, U., Remke, M., Wolf, J. and Schramm, A.
Scientific Reports 10
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28 April 2020
New algorithms improving PML risk stratification in MS patients treated with natalizumab.
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Frontiers in Neurology 11
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17 December 2020
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage.
Toboso-Navasa, A., Gunawan, A., Morlino, G., Nakagawa, R., Taddei, A., Damry, D., Patel, Y., Chakravarty, P., Janz, M., Kassiotis, G., Brink, R., Eilers, M. and Calado, D.P.
Journal of Experimental Medicine 217
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6 July 2020
Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells.
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July 2020
Identification of a novel titin-cap/telethonin mutation in a Portuguese family with hypertrophic cardiomyopathy.
Toste, A., Perrot, A., Özcelik, C. and Cardim, N.
Revista Portuguesa de Cardiologia 39
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June 2020
Norman M. Kaplan: January 2, 1931-April 5, 2020.
Townsend, R.R., DiPette, D.J., Luft, F.C., Weinberger, M.H. and Ram, V.
Hypertension 76
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August 2020
CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia.
Tran, N.T., Graf, R., Wulf-Goldenberg, A., Stecklum, M., Strauß, G., Kühn, R., Kocks, C., Rajewsky, K. and Chu, V.T.
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2 December 2020
Protocol for efficient CRISPR/Cas9/AAV-mediated homologous recombination in mouse hematopoietic stem and progenitor cells.
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STAR Protocols 1
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19 June 2020
Could electrical coupling contribute to the formation of cell assemblies?
Traub, R.D., Whittington, M.A., Maier, N., Schmitz, D. and Nagy, J.I.
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February 2020
O-Vanillin attenuates the TLR2 mediated tumor-promoting phenotype of microglia.
Triller, P., Bachorz, J., Synowitz, M., Kettenmann, H. and Markovic, D.
International Journal of Molecular Sciences 21
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22 April 2020
The NEMP family supports metazoan fertility and nuclear envelope stiffness.
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28 August 2020
R-chie: a web server and R package for visualizing cis and trans RNA-RNA, RNA-DNA and DNA-DNA interactions.
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9 October 2020
Therapeutic targeting of preleukemia cells in a mouse model of mutant acute myeloid leukemia.
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31 January 2020
Rapid and deep-scale ubiquitylation profiling for biology and translational research.
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Nature Communications 11
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17 January 2020
De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome.
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November 2020
Health care utilisation and medication one year after myocardial infarction in Germany - a claims data analysis.
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International Journal of Cardiology 300
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1 February 2020
Teichoic acids anchor distinct cell wall lamellae in an apically growing bacterium.
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covRNA: discovering covariate associations in large-scale gene expression data.
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24 February 2020
Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques.
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June 2020
Phrenic-specific transcriptional programs shape respiratory motor output.
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Blockade of endogenous angiotensin II type I receptor agonistic autoantibody activity improves mitochondria reactive oxygen species and hypertension in a rat model of preeclampsia.
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27 January 2020
Methods for automated single cell isolation and sub-cloning of human pluripotent stem cells.
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December 2020
Opposite macrophage polarization in different subsets of ovarian cancer: observation from a pilot study.
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Cells 9
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27 January 2020
Angiotensin-(1-7) induces beige fat thermogenesis through the Mas receptor.
Vargas-Castillo, A., Tobon-Cornejo, S., Del Valle-Mondragon, L., Torre-Villalvazo, I., Schcolnik-Cabrera, A., Guevara-Cruz, M., Pichardo-Ontiveros, E., Fuentes-Romero, R., Bader, M., Alenina, N., Vidal-Puig, A., Hong, E., Torres, N. and Tovar, A.R.
Metabolism 103
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February 2020
Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites.
Veenvliet, J.V., Bolondi, A., Kretzmer, H., Haut, L., Scholze-Wittler, M., Schifferl, D., Koch, F., Guignard, L., Kumar, A.S., Pustet, M., Heimann, S., Buschow, R., Wittler, L., Timmermann, B., Meissner, A. and Herrmann, B.G.
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11 December 2020
Megadalton-sized dityrosine aggregates of α-synuclein retain high degrees of structural disorder and internal dynamics.
Verzini, S., Shah, M., Theillet, F.X., Belsom, A., Bieschke, J., Wanker, E.E., Rappsilber, J., Binolfi, A. and Selenko, P.
Journal of Molecular Biology 432
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4 December 2020
The association between salt taste perception, mediterranean diet and metabolic syndrome: a cross-sectional study.
Veček, N.N., Mucalo, L., Dragun, R., Miličević, T., Pribisalić, A., Patarčić, I., Hayward, C., Polašek, O. and Kolčić, I.
Nutrients 12
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April 2020
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis.
Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S.K., Assmann, K., Valles-Colomer, M., Nguyen, T..D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J.P., Coelho, L.P., Galleron, N., Hansen, T.H., Hulot, J.S., Lewinter, C., Pedersen, H.K., Quinquis, B., Rouault, C., Roume, H., Salem, J.E., Søndertoft, N.B., Touch, S., Dumas, M.E., Ehrlich, S.D., Galan, P., Gøtze, J.P., Hansen, T., Holst, J.J., Køber, L., Letunic, I., Nielsen, J., Oppert, J.M., Stumvoll, M., Vestergaard, H., Zucker, J.D., Bork, P., Pedersen, O., Bäckhed, F., Clément, K. and Raes, J.
Nature 581
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21 May 2020
LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.
Vinckier, N.K., Patel, N.A., Geusz, R.J., Wang, A., Wang, J., Matta, I., Harrington, A.R., Wortham, M., Wetton, N., Wang, J., Jhala, U.S., Rosenfeld, M.G., Benner, C.W., Shih, H.P. and Sander, M.
Nature Communications 11
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29 April 2020
Improved assembly and variant detection of a haploid human genome using single-molecule, high-fidelity long reads.
Vollger, M.R., Logsdon, G.A., Audano, P.A., Sulovari, A., Porubsky, D., Peluso, P., Wenger, A.M., Concepcion, G.T., Kronenberg, Z.N., Munson, K.M., Baker, C., Sanders, A.D., Spierings, D.C.J., Lansdorp, P.M., Surti, U., Hunkapiller, M.W. and Eichler, E.E.
Annals of Human Genetics 84
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March 2020
The role of orthosteric building blocks of bitopic ligands for muscarinic M1 receptors.
Volpato, D., Kauk, M., Messerer, R., Bermudez, M., Wolber, G., Bock, A., Hoffmann, C. and Holzgrabe, U.
ACS Omega 5
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15 December 2020
Sex differences in brain atrophy in multiple sclerosis.
Voskuhl, R.R., Patel, K., Paul, F., Gold, S.M., Scheel, M., Kuchling, J., Cooper, G., Asseyer, S., Chien, C., Brandt, A.U., Meyer, C.E. and MacKenzie-Graham, A.
Biology of Sex Differences 11
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28 August 2020
ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP.
Völker, L.A., Kaufeld, J., Miesbach, W., Brähler, S., Reinhardt, M., Kühne, L., Mühlfeld, A., Schreiber, A., Gaedeke, J., Tölle, M., Jabs, W.J., Özcan, F., Markau, S., Girndt, M., Bauer, F., Westhoff, T.H., Felten, H., Hausberg, M., Brand, M., Gerth, J., Bieringer, M., Bommer, M., Zschiedrich, S., Schneider, J., Elitok, S., Gawlik, A., Gäckler, A., Kribben, A., Schwenger, V., Schoenermarck, U., Roeder, M., Radermacher, J., Bramstedt, J., Morgner, A., Herbst, R., Harth, A., Potthoff, S.A., von Auer, C., Wendt, R., Christ, H., Brinkkoetter, P.T. and Menne, J.
Blood Advances 4
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14 July 2020
Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura.
Völker, L.A., Kaufeld, J., Miesbach, W., Brähler, S., Reinhardt, M., Kühne, L., Mühlfeld, A., Schreiber, A., Gaedeke, J., Tölle, M., Jabs, W.J., Özcan, F., Markau, S., Girndt, M.., Bauer, F., Westhoff, T.H., Felten, H., Hausberg, M., Brand, M., Gerth, J., Bieringer, M., Bommer, M., Zschiedrich, S., Schneider, J., Elitok, S., Gawlik, A., Gäckler, A., Kribben, A., Schwenger, V., Schoenermarck, U., Roeder, M., Radermacher, J., Bramstedt, J., Morgner, A., Herbst, R., Harth, A., Potthoff, S.A., von Auer, C., Wendt, R., Christ, H., Brinkkoetter, P.T. and Menne, J.
Blood Advances 4
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14 July 2020
Preclinical lead optimization of a 1,2,4-triazole based tankyrase inhibitor.
Waaler, J., Leenders, R., Sowa, S.T., Alam Brinch, S., Lycke, M., Nieczypor, P., Aertssen, S., Murthy, S., Galera-Prat, A., Damen, E., Wegert, A., Nazare, M., Lehtiö, L. and Krauss, S.
Journal of Medicinal Chemistry 63
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9 July 2020
Altered coupling of psychological relaxation and regional volume of brain reward areas in multiple sclerosis.
Wakonig, K., Eitel, F., Ritter, K., Hetzer, S., Schmitz-Hübsch, T., Bellmann-Strobl, J., Haynes, J.D., Brandt, A.U., Gold, S.M., Paul, F. and Weygandt, M.
Frontiers in Neurology 11
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6 October 2020
Purifying selection against pathogenic mitochondrial DNA in human T cells.
Walker, M.A., Lareau, C.A., Ludwig, L.S., Karaa, A., Sankaran, V.G., Regev, A. and Mootha, V.K.
New England Journal of Medicine 383
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15 October 2020
In-vitro and in-vivo investigations into the carbene-gold anticancer drug candidates NHC*-Au-SCSNMe(2) and NHC*-Au-S-GLUC against advanced prostate cancer PC3.
Walther, W., Althagafi, D., Curran, D., O'Beirne, C., Mc Carthy, C., Ott, I., Basu, U., Büttner, B., Sterner-Kock, A., Müller-Bunz, H., Sánchez-Sanz, G., Zhu, X. and Tacke, M.
Anti-Cancer Drugs 31
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August 2020
Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements.
Wang, H., Georgakopoulou, A., Li, C., Liu, Z., Gil, S., Bashyam, A., Yannaki, E., Anagnostopoulos, A., Pande, A., Izsvák, Z., Papayannopoulou, T. and Lieber, A.
JCI Insight 5
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20 August 2020
Mutations in SREBF1, encoding sterol regulatory element binding transcription factor 1, cause autosomal-dominant IFAP syndrome.
Wang, H., Humbatova, A., Liu, Y., Qin, W., Lee, M., Cesarato, N., Kortüm, F., Kumar, S., Romano, M.T., Dai, S., Mo, R., Sivalingam, S., Motameny, S., Wu, Y., Wang, X., Niu, X., Geng, S., Bornholdt, D., Kroisel, P.M., Tadini, G., Walter, S.D., Hauck, F., Girisha, K.M., Calza, A.M., Bottani, A., Altmüller, J., Buness, A., Yang, S., Sun, X., Ma, L., Kutsche, K., Grzeschik, K.H., Betz, R.C. and Lin, Z.
American Journal of Human Genetics 107
(1): 34-45.
2 July 2020
YAP and TAZ protect against white adipocyte cell death during obesity.
Wang, L., Wang, S.P., Shi, Y., Li, R., Günther, S., Ong, Y.T., Potente, M., Yuan, Z., Liu, E. and Offermanns, S.
Nature Communications 11
(1): 5455.
28 October 2020
MR elastography-based assessment of matrix remodeling at lesion sites associated with clinical severity in a model of multiple sclerosis.
Wang, S., Millward, J.M., Hanke-Vela, L., Malla, B., Pilch, K., Gil-Infante, A., Waiczies, S., Mueller, S., Boehm-Sturm, P., Guo, J., Sack, I. and Infante-Duarte, C.
Frontiers in Neurology 10
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13 January 2020
Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility.
Warren, W.C., Harris, R.A., Haukness, M., Fiddes, I.T., Murali, S.C., Fernandes, J., Dishuck, P.C., Storer, J.M, Raveendran, M., Hillier, L.W., Porubsky, D., Mao, Y., Gordon, D., Vollger, M.R., Lewis, A.P., Munson, K.M., DeVogelaere, E., Armstrong, J., Diekhans, M., Walker, J.A., Tomlinson, C., Graves-Lindsay, T.A., Kremitzki, M., Salama, S.R., Audano, P.A., Escalona, M., Maurer, N.W., Antonacci, F., Mercuri, L., Maggiolini, F.A.M., Catacchio, C.R., Underwood, J.G., O'Connor, D.H., Sanders, A.D., Korbel, J.O., Ferguson, B., Kubisch, H.M., Picker, L., Kalin, N.H., Rosene, D., Levine, J., Abbott, D.H., Gray, S.B., Sanchez, M.M., Kovacs-Balint, Z.A., Kemnitz, J.W., Thomasy, S.M., Roberts, J.A., Kinnally, E.L., Capitanio, J.P., Skene, J.H.Pate, Platt, M., Cole, S.A., Green, R.E., Ventura, M., Wiseman, R.W., Paten, B., Batzer, M.A., Rogers, J. and Eichler, E.E.
Science 370
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18 December 2020
Comparative analysis of the secretome and interactome of Trypanosoma cruzi and Trypanosoma rangeli reveals species specific immune response modulating proteins.
Watanabe Costa, R., Batista, M.F., Meneghelli, I., Vidal, R.O., Nájera, C.A., Mendes, A.C., Andrade-Lima, I.A., da Silveira, J.F., Lopes, L.R., Ferreira, L.R.P., Antoneli, F. and Bahia, D.
Frontiers in Immunology 11
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27 August 2020
Pervasive chromosomal instability and karyotype order in tumour evolution.
Watkins, T.B.K., Lim, E.L., Petkovic, M., Elizalde, S., Birkbak, N.J., Wilson, G.A., Moore, D.A., Grönroos, E., Rowan, A., Dewhurst, S.M., Demeulemeester, J., Dentro, S.C., Horswell, S., Au, L., Haase, K., Escudero, M., Rosenthal, R., Bakir, M.A., Xu, H., Litchfield, K., Lu, W.T., Mourikis, T.P., Dietzen, M., Spain, L., Cresswell, G.D., Biswas, D., Lamy, P., Nordentoft, I., Harbst, K., Castro-Giner, F., Yates, L.R., Caramia, F., Jaulin, F., Vicier, C., Tomlinson, I.P.M., Brastianos, P.K., Cho, R.J., Bastian, B.C., Dyrskjøt, L., Jönsson, G.B., Savas, P., Loi, S., Campbell, P.J., Andre, F., Luscombe, N.M., Steeghs, N., Tjan-Heijnen, V.C.G., Szallasi, Z., Turajlic, S., Jamal-Hanjani, M., Van Loo, P., Bakhoum, S.F., Schwarz, R.F., McGranahan, N. and Swanton, C.
Nature 587
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5 November 2020
Revealing cytotoxic substructures in molecules using deep learning.
Webel, H.E., Kimber, T.B., Radetzki, S., Neuenschwander, M., Nazaré, M. and Volkamer, A.
Journal of Computer-Aided Molecular Design 34
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July 2020
PEDL: extracting protein-protein associations using deep language models and distant supervision.
Weber, L., Thobe, K., Migueles Lozano, O.A., Wolf, J. and Leser, U.
Bioinformatics 36
(Suppl 1): i490-i498.
July 2020
4EHP and GIGYF1/2 mediate translation-coupled messenger RNA decay.
Weber, R., Chung, M.Y., Keskeny, C., Zinnall, U., Landthaler, M., Valkov, E., Izaurralde, E. and Igreja, C.
Cell Reports 33
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13 October 2020
Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.
Weinert, S., Gimber, N., Deuschel, D., Stuhlmann, T., Puchkov, D., Farsi, Z., Ludwig, C.F., Novarino, G., López-Cayuqueo, K.I., Planells-Cases, R. and Jentsch, T.J.
EMBO Journal 39
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4 May 2020
In vivo potassium MRI of the human heart.
Wenz, D., Nagel, A.M., Lott, J., Kuehne, A., Niesporek, S.C. and Niendorf, T.
Magnetic Resonance in Medicine 83
(1): 203-213.
January 2020
Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice.
Wenzel, J., Hansen, C.E., Bettoni, C., Vogt, M.A., Lembrich, B., Natsagdorj, R., Huber, G., Brands, J., Schmidt, K., Assmann, J.C., Stölting, I., Saar, K., Sedlacik, J., Fiehler, J., Ludewig, P., Wegmann, M., Feller, N., Richter, M., Müller-Fielitz, H., Walther, T., König, G.M., Kostenis, E., Raasch, W., Hübner, N., Gass, P., Offermanns, S., de Wit, C., Wagner, C.A. and Schwaninger, M.
Proceedings of the National Academy of Sciences of the United States of America 117
(3): 1753-1761.
21 January 2020
Integrative functional genomics decodes herpes simplex virus 1.
Whisnant, A.W., Jürges, C.S., Hennig, T., Wyler, E., Prusty, B., Rutkowski, A.J., L'hernault, A., Djakovic, L., Göbel, M., Döring, K., Menegatti, J., Antrobus, R., Matheson, N.J., Künzig, F.W.H., Mastrobuoni, G., Bielow, C., Kempa, S., Liang, C., Dandekar, T., Zimmer, R., Landthaler, M., Grässer, F., Lehner, P.J., Friedel, C.C., Erhard, F. and Dölken, L.
Nature Communications 11
(1): 2038.
27 April 2020
Treatment of MOG-IgG-associated disorder with rituximab: an international study of 121 patients.
Whittam, D.H., Cobo-Calvo, A., Lopez-Chiriboga, A.S., Pardo, S., Gornall, M., Cicconi, S., Brandt, A., Berek, K., Berger, T., Jelcic, I., Gombolay, G., Oliveira, L.M., Callegaro, D., Kaneko, K., Misu, T., Capobianco, M., Gibbons, E., Karthikeayan, V., Brochet, B., Audoin, B., Mathey, G., Laplaud, D., Thouvenot, E., Cohen, M., Tourbah, A., Maillart, E., Ciron, J., Deschamps, R., Biotti, D., Rostasy, K., Neuteboom, R., Hemingway, C., Forsyth, R., Matiello, M., Webb, S., Hunt, D., Murray, K., Hacohen, Y., Lim, M., Leite, M.I., Palace, J., Solomon, T., Lutterotti, A., Fujihara, K., Nakashima, I., Bennett, J.L., Pandit, L., Chitnis, T., Weinshenker, B.G., Wildemann, B., Sato, D.K., Kim, S.H., Huda, S., Kim, H.J., Reindl, M., Levy, M., Jarius, S., Tenembaum, S., Paul, F., Pittock, S., Marignier, R. and Jacob, A.
Multiple Sclerosis and Related Disorders 44
: 102251.
September 2020
Treatment of MOG antibody associated disorders: results of an international survey.
Whittam, D.H., Karthikeayan, V., Gibbons, E., Kneen, R., Chandratre, S., Ciccarelli, O., Hacohen, Y., de Seze, J., Deiva, K., Hintzen, R.Q., Wildemann, B., Jarius, S., Kleiter, I., Rostasy, K., Huppke, P., Hemmer, B., Paul, F., Aktas, O., Pröbstel, A.K., Arrambide, G., Tintore, M., Amato, M.P., Nosadini, M., Mancardi, M.M., Capobianco, M., Illes, Z., Siva, A., Altintas, A., Akman-Demir, G., Pandit, L., Apiwattankul, M., Hor, J.Y., Viswanathan, S., Qiu, W., Kim, H.J., Nakashima, I., Fujihara, K., Ramanathan, S., Dale, R.C., Boggild, M., Broadley, S., Lana-Peixoto, M.A., Sato, D.K., Tenembaum, S., Cabre, P., Wingerchuk, D.M., Weinshenker, B.G., Greenberg, B., Matiello, M., Klawiter, E.C., Bennett, J.L., Wallach, A.I., Kister, I., Banwell, B.L., Traboulsee, A., Pohl, D., Palace, J., Leite, M.I., Levy, M., Marignier, R., Solomon, T., Lim, M., Huda, S. and Jacob, A.
Journal of Neurology 367
(12): 3565-3577.
December 2020
Personen mit Migrationshintergrund in der NAKO Gesundheitsstudie – soziodemografische Merkmale und Vergleiche mit der autochthonen deutschen Bevölkerung [Persons with migration background in the German National Cohort (NAKO)-sociodemographic characteristics and comparisons with the German autochthonous population].
Wiessner, C., Keil, T., Krist, L., Zeeb, H., Dragano, N., Schmidt, B., Ahrens, W., Berger, K., Castell, S., Fricke, J., Führer, A., Gastell, S., Greiser, H., Guo, F., Jaeschke, L., Jochem, C., Jöckel, K.H., Kaaks, R., Koch-Gallenkamp, L., Krause, G., Kuss, O., Legath, N., Leitzmann, M., Lieb, W., Meinke-Franze, C., Meisinger, C., Mikolajczyk, R., Obi, N., Pischon, T., Schipf, S., Schmoor, C., Schramm, S., Schulze, M.B., Sowarka, N., Waniek, S., Wigmann, C., Willich, S.N. and Becher, H.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(3): 279-289.
March 2020
Sclerotiorin stabilizes the assembly of nonfibrillar Abeta42 oligomers with low toxicity, seeding activity, and beta-sheet content.
Wiglenda, T., Groenke, N., Hoffmann, W., Manz, C., Diez, L., Buntru, A., Brusendorf, L., Neuendorf, N., Schnoegl, S., Haenig, C., Schmieder, P., Pagel, K. and Wanker, E.E.
Journal of Molecular Biology 432
(7): 2080-2098.
27 March 2020
Der Einfluss der Mikrobiota auf den Blutdruck : Wie Darmbakterien Bluthochdruck und Organschäden beeinflussen.
Wilck, N.
Dialyse aktuell 24
(9): 360-366.
November 2020
S100A8 and S100A9 are important for postnatal development of gut microbiota and immune system in mice and infants.
Willers, M., Ulas, T., Völlger, L., Vogl, T., Heinemann, A.S., Pirr, S., Pagel, J., Fehlhaber, B., Halle, O., Schöning, J., Schreek, S., Löber, U., Essex, M., Hombach, P., Graspeuntner, S., Basic, M., Bleich, A., Cloppenborg-Schmidt, K., Künzel, S., Jonigk, D., Rupp, J., Hansen, G., Förster, R., Baines, J.F., Härtel, C., Schultze, J.L., Forslund, S.K., Roth, J. and Viemann, D.
Gastroenterology 159
(6): 2130-2145.
December 2020
Endogenous retrovirus-derived lncRNA BANCR promotes cardiomyocyte migration in humans and non-human primates.
Wilson, K.D., Ameen, M., Guo, H., Abilez, O.J., Tian, L., Mumbach, M.R., Diecke, S., Qin, X., Liu, Y., Yang, H., Ma, N., Gaddam, S., Cunningham, N.J., Gu, M., Neofytou, E., Prado, M., Hildebrandt, T.B., Karakikes, I., Chang, H.Y. and Wu, J.C.
Developmental Cell 54
(6): 694-709.
28 September 2020
4D flow imaging with UNFOLD in a reduced FOV.
Wink, C., Bassenge, J.P., Ferrazzi, G., Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 84
(1): 327-338.
July 2020
Nächtliche Verkehrslärmbelästigung in Deutschland: individuelle und regionale Unterschiede in der NAKO Gesundheitsstudie [Nighttime transportation noise annoyance in Germany: personal and regional differences in the German National Cohort Study.
Wolf, K., Kraus, U., Dzolan, M., Bolte, G., Lakes, T., Schikowski, T., Greiser, K., Kuß, O., Ahrens, W., Bamberg, F., Becher, H., Berger, K., Brenner, H., Castell, S., Damms-Machado, A., Fischer, B., Franzke, C., Gastell, S., Günther, K., Holleczek, B., Jaeschke, L., Kaaks, R., Keil, T., Kemmling, Y., Krist, L., Legath, N., Leitzmann, M., Lieb, W., Loeffler, M., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Moebus, S., Mueller, U., Obi, N., Pischon, T., Rathmann, W., Schipf, S., Schmidt, B., Schulze, M., Thiele, I., Thierry, S., Waniek, S., Wigmann, C., Wirkner, K., Zschocke, J., Peters, A. and Schneider, A.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(3): 332-343.
March 2020
Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus.
Wu, G., Gotthardt, M. and Gollasch, M.
Scientific Reports 10
(1): 18784.
2 November 2020
Wegbereiter der modernen Krebsforschung: Theodor Boveri und Otto Warburg [Pioneers of modern cancer research: Theodor Boveri and Otto Warburg].
Wunderlich, V.
BIOspektrum 26
(6): 687-690.
November 2020
50 Jahre Reverse Transkriptase [50 years of reverse transcriptase].
Wunderlich, V.
BIOspektrum 26
(3): 343-344.
May 2020
Clinical outcome in patients with carcinoma of the esophagogastric junction treated with neoadjuvant radiochemotherapy or perioperative chemotherapy: a two-enter retrospective analysis.
Wundsam, H.V., Doleschal, B., Prommer, R., Venhoda, C., Schmitt, C., Petzer, A., Metz-Gercek, S. and Rumpold, H.
Oncology 98
(10): 706-713.
October 2020
SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis.
Wurmser, M., Chaverot, N., Madani, R., Sakai, H., Negroni, E., Demignon, J., Saint-Pierre, B., Mouly, V., Amthor, H., Tapscott, S., Birchmeier, C., Tajbakhsh, S., Le Grand, F., Sotiropoulos, A. and Maire, P.
Development 147
(19): dev185975.
9 October 2020
Non-thermal effects of radiofrequency electromagnetic fields.
Wust, P., Kortüm, B., Strauss, U., Nadobny, J., Zschaeck, S., Beck, M., Stein, U. and Ghadjar, P.
Scientific Reports 10
(1): 13488.
10 August 2020
Unmasking features of the auto-epitope essential for β(1)-adrenoceptor activation by autoantibodies in chronic heart failure.
Wölfel, A., Sättele, M., Zechmeister, C., Nikolaev, V.O., Lohse, M.J., Boege, F., Jahns, R. and Boivin-Jahns, V.
ESC Heart Failure 7
(4): 1830-1841.
August 2020
hGBP1 coordinates chlamydia restriction and inflammasome activation through sequential GTP hydrolysis.
Xavier, A., Al-Zeer, M.A., Meyer, T.F. and Daumke, O.
Cell Reports 31
(7): 107667.
19 May 2020
Identification of glioma cancer stem cell characteristics based on weighted gene prognosis module co-expression network analysis of transcriptome data stemness indices.
Xia, P., Li, Q., Wu, G. and Huang, Y.
Journal of Molecular Neuroscience 70
(10): 1512-1520.
October 2020
Dual-mode detection of bacterial 16S ribosomal RNA in tissues.
Xu, S., Zhang, Q., Han, X., Wang, Y., Wang, X., Nazaré, M., Jiang, J.D. and Hu, H.Y.
ACS Sensors 5
(6): 1650-1656.
26 June 2020
Overactivation of the NF-κB pathway impairs molar enamel formation.
Yamada, A., Kawasaki, M., Miake, Y., Yamada, Y., Blackburn, J., Kawasaki, K., Trakanant, S., Nagai, T., Nihara, J., Kudo, T., Meguro, F., Schmidt-Ullrich, R., Liu, B., Hu, Y., Page, A., Ramírez, Á., Sharpe, P.T., Maeda, T., Takagi, R. and Ohazama, A.
Oral Diseases 26
(7): 1513-1522.
October 2020
PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response.
Ye, J., Huang, A., Wang, H., Zhang, A.M.Y., Huang, X., Lan, Q., Sato, T., Goyama, S., Kurokawa, M., Deng, C., Sander, M., Schaeffer, D.F., Li, W., Kopp, J.L. and Xie, R.
Cell death and disease 11
(3): 187.
16 March 2020
The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype.
Yigit, G., Saida, K., DeMarzo, D., Miyake, N., Fujita, A., Yang Tan, T., White, S.M., Wadley, A., Toliat, M.R., Motameny, S., Franitza, M., Stutterd, C.A., Chong, P.F., Kira, R., Sengoku, T., Ogata, K., Guillen Sacoto, M.J., Fresen, C., Beck, B.B., Nürnberg, P., Dieterich, C., Wollnik, B., Matsumoto, N. and Altmüller, J.
Human Mutation 41
(3): 591-599.
March 2020
Monensin, a novel potent MYB inhibitor, suppresses proliferation of acute myeloid leukemia and adenoid cystic carcinoma cells.
Yusenko, M.V., Trentmann, A., Andersson, M.K., Ghani, L.A., Jakobs, A., Arteaga Paz, M.F., Mikesch, J.H., von Kries, J.P., Stenman, G. and Klempnauer, K.H.
Cancer Letters 479
: 61-70.
1 June 2020
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf, R.Z., Saez, B., Sharda, A., van Gastel, N., Yu, V.W.C., Baryawno, N., Scadden, E.W., Acharya, S., Chattophadhyay, S., Huang, C., Viswanathan, V., S'aulis, D., Cobert, J., Sykes, D.B., Keibler, M.A., Das, S., Hutchinson, J.N., Churchill, M., Mukherjee, S., Lee, D., Mercier, F., Doench, J., Bullinger, L., Logan, D.J., Schreiber, S., Stephanopoulos, G., Rizzo, W.B. and Scadden, D.T.
Blood 136
(11): 1303-1316.
10 September 2020
Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta.
Yvernogeau, L., Klaus, A., Maas, J., Morin-Poulard, I., Weijts, B., Schulte-Merker, S., Berezikov, E., Junker, J.P. and Robin, C.
Blood 136
(7): 831-844.
13 August 2020
Ketamine effects on default mode network activity and vigilance: a randomized, placebo-controlled crossover simultaneous fMRI/EEG study.
Zacharias, N., Musso, F., Müller, F., Lammers, F., Saleh, A., London, M., de Boer, P. and Winterer, G.
Human Brain Mapping 41
(1): 107-119.
January 2020
Vasodilation of rat skeletal muscle arteries by the novel BK channel opener GoSlo is mediated by the simultaneous activation of BK and Kv7 channels.
Zavaritskaya, O., Dudem, S., Ma, D., Kaneez, R.E., Albrecht, S., Tsvetkov, D., Kassmann, M., Thornbury, K., Mladenov, M., Kammermeier, C., Sergeant, G., Mullins, N., Wouappi, O., Wurm, H., Kannt, A., Gollasch, M., Hollywood, M.A. and Schubert, R.
British Journal of Pharmacology 177
(5): 1164-1186.
March 2020
Monogenic variants in dystonia: an exome-wide sequencing study.
Zech, M., Jech, R., Boesch, S., Škorvánek, M., Weber, S., Wagner, M., Zhao, C., Jochim, A., Necpál, J., Dincer, Y., Vill, K., Distelmaier, F., Stoklosa, M., Krenn, M., Grunwald, S., Bock-Bierbaum, T., Fečíková, A., Havránková, P., Roth, J., Příhodová, I., Adamovičová, M., Ulmanová, O., Bechyně, K., Danhofer, P., Veselý, B., Haň, V., Pavelekova, P., Gdovinová, Z., Mantel, T., Meindl, T., Sitzberger, A., Schröder, S., Blaschek, A., Roser, T., Bonfert, M.V., Haberlandt, E., Plecko, B., Leineweber, B., Berweck, S., Herberhold, T., Langguth, B., Švantnerová, J., Minár, M., Ramos-Rivera, G.A., Wojcik, M.H., Pajusalu, S., Õunap, K., Schatz, U.A., Pölsler, L., Milenkovic, I., Laccone, F., Pilshofer, V., Colombo, R., Patzer, S., Iuso, A., Vera, J., Troncoso, M., Fang, F., Prokisch, H., Wilbert, F., Eckenweiler, M., Graf, E., Westphal, D.S., Riedhammer, K.M., Brunet, T., Alhaddad, B., Berutti, R., Strom, T.M., Hecht, M., Baumann, M., Wolf, M., Telegrafi, A., Person, R.E., Zamora, F.M., Henderson, L.B., Weise, D., Musacchio, T., Volkmann, J., Szuto, A., Becker, J., Cremer, K., Sycha, T., Zimprich, F., Kraus, V., Makowski, C., Gonzalez-Alegre, P., Bardakjian, T.M., Ozelius, L.J., Vetro, A., Guerrini, R., Maier, E., Borggraefe, I., Kuster, A., Wortmann, S.B., Hackenberg, A., Steinfeld, R., Assmann, B., Staufner, C., Opladen, T., Růžička, E., Cohn, R.D., Dyment, D., Chung, W.K., Engels, H., Ceballos-Baumann, A., Ploski, R., Daumke, O., Haslinger, B., Mall, V., Oexle, K. and Winkelmann, J.
Lancet Neurology 19
(11): 908-918.
November 2020
Long noncoding RNA TYKRIL plays a role in pulmonary hypertension via the p53-mediated regulation of PDGFRβ.
Zehendner, C.M., Valasarajan, C., Werner, A., Boeckel, J.N., Bischoff, F.C., John, D., Weirick, T., Glaser, S.F., Rossbach, O., Jaé, N., Demolli, S., Khassafi, F., Yuan, K., de Jesus Perez, V.A., Michalik, K.M., Chen, W., Seeger, W., Guenther, A., Wasnick, R.M., Uchida, S., Zeiher, A.M., Dimmeler, S. and Pullamsetti, S.S.
American Journal of Respiratory and Critical Care Medicine 202
(10): 1445-1457.
15 November 2020
Phase separation of a PKA regulatory subunit controls cAMP compartmentation and oncogenic signaling.
Zhang, J.Z., Lu, T.W., Stolerman, L.M., Tenner, B., Yang, J.R., Zhang, J.F., Falcke, M., Rangamani, P., Taylor, S.S., Mehta, S. and Zhang, J.
Cell 182
(6): 1531-1544.
17 September 2020
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Zhang, Y., Chen, F., Fonseca, N.A., He, Y., Fujita, M., Nakagawa, H., Zhang, Z., Brazma, A. and Creighton, C.J.
Nature Communications 11
(1): 736.
5 February 2020
Transfer of cGAMP into bystander cells via LRRC8 volume-regulated anion channels augments STING-mediated interferon responses and anti-viral immunity.
Zhou, C., Chen, X., Planells-Cases, R., Chu, J., Wang, L., Cao, L., Li, Z., López-Cayuqueo, K.I., Xie, Y., Ye, S., Wang, X., Ullrich, F., Ma, S., Fang, Y., Zhang, X., Qian, Z., Liang, X., Cai, S.Q., Jiang, Z., Zhou, D., Leng, Q., Xiao, T.S., Lan, K., Yang, Ji., Li, H., Peng, C., Qiu, Z., Jentsch, T.J. and Xiao, H.
Immunity 52
(5): 767-781.
19 May 2020
Assessment of ethanol-induced toxicity on iPSC-derived human dopaminergic neurons using a novel high-throughput mitochondrial neuronal health (MNH) assay.
Zink, A., Conrad, J., Telugu, N.S., Diecke, S., Heinz, A., Wanker, E., Priller, J. and Prigione, A.
Frontiers in Cell and Developmental Biology 8
: 590540.
5 November 2020
Sinusoidal obstruction syndrome following myeloablative therapy and tranexamic acid treatment for hemorrhage in two patients with neuroblastoma.
Zirngibl, F., Flemmig, C., Lang, P., Künkele, A., Eggert, A., Schulte, J.H. and Deubzer, H.E.
Children 7
(11): 198.
November 2020
B(1) and B(2) kinin receptor blockade improves psoriasis-like disease.
da Silva Soley, B., Silva, L.M., Mendes, D.A.G.B., Báfica, A., Pesquero, J.B., Bader, M., Witherden, D.A., Havran, W.L., Calixto, J.B., Otuki, M.F. and Cabrini, D.A.
British Journal of Pharmacology 177
(15): 3535-3551.
August 2020
C/EBPβ-dependent epigenetic memory induces trained immunity in hematopoietic stem cells.
de Laval, B., Maurizio, J., Kandalla, P.K., Brisou, G., Simonnet, L., Huber, C., Gimenez, G., Matcovitch-Natan, O., Reinhardt, S., David, E., Mildner, A., Leutz, A., Nadel, B., Bordi, C., Amit, I., Sarrazin, S. and Sieweke, M.H.
Cell Stem Cell 26
(5): 657-674.
May 2020
USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells.
van den Berk, P., Lancini, C., Company, C., Serresi, M., Sanchez-Bailon, M.P., Hulsman, D., Pritchard, C., Song, J.Y., Schmitt, M.J., Tanger, E., Popp, O., Mertins, P., Huijbers, I.J., Jacobs, H., van Lohuizen, M., Gargiulo, G. and Citterio, E.
Cell Reports 33
(13): 108533.
29 December 2020
Deleting titin's C-terminal PEVK exons increases passive stiffness, alters splicing, and induces cross-sectional and longitudinal hypertrophy in skeletal muscle.
van der Pijl, R.J., Hudson, B., Granzier-Nakajima, T., Li, F., Knottnerus, A.M., Smith, J., Chung, C.S., Gotthardt, M., Granzier, H.L. and Ottenheijm, C.A.C.
Frontiers in Physiology 11
(1): 494.
29 May 2020
DLC1 is a direct target of activated YAP/TAZ that drives collective migration and sprouting angiogenesis.
van der Stoel, M., Schimmel, L., Nawaz, K., van Stalborch, A.M., de Haan, A., Klaus-Bergmann, A., Valent, E.T., Koenis, D.S., van Nieuw Amerongen, G.P., de Vries, C.J., de Waard, V., Gloerich, M., van Buul, J.D. and Huveneers, S.
Journal of Cell Science 133
(3): jcs239947.
12 February 2020
The role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a Position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC).
Čelutkienė, J., Pudil, R., López-Fernández, T., Grapsa, J., Nihoyannopoulos, P., Bergler-Klein, J., Cohen-Solal, A., Farmakis, D., Tocchetti, C.G., von Haehling, S., Barberis, V., Flachskampf, F.A., Čeponienė, I., Haegler-Laube, E., Suter, T., Lapinskas, T., Prasad, S., de Boer, R.A., Wechalekar, K., Anker, M.S., Iakobishvili, Z., Buccarelli-Ducci, C., Schulz-Menger, J., Cosyns, B., Gaemperli, O., Belenkov, Y., Hulot, J.S., Galderisi, M., Lancellotti, P., Bax, J., Marwick, T.H., Chioncel, O., Jaarsma, T., Mullens, W., Piepoli, M., Thum, T., Heymans, S., Mueller, C., Moura, B., Ruschitzka, F., Zamorano, J.L., Rosano, G., Coats, A.J.S., Asteggiano, R., Seferovic, P., Edvardsen, T. and Lyon, A.R.
European Journal of Heart Failure 22
(9): 1504-1524.
September 2020
Norditerpenoids with selective anti-cholinesterase activity from the roots of Perovskia atriplicifolia Benth.
Ślusarczyk, S., Senol Deniz, F.S., Abel, R., Pecio, Ł., Pérez-Sánchez, H., Cerón-Carrasco, J.P., den-Haan, H., Banerjee, P., Preissner, R., Krzyżak, E., Oleszek, W., E Orhan, I. and Matkowski, A.
International Journal of Molecular Sciences 21
(12): 4475.
23 June 2020
Book Section
Erkrankungen der Niere: Renale Vaskulopathien einschließlich Vaskulitiden.
Kettritz, R., Mertens, P.R. and Haubitz, M.
In:
Rationelle Diagnostik und Therapie in der Inneren Medizin.
Elsevier, Munich, G6-1-G6-4.
ISBN 978-3-437-06282-7
2020
Hypnotika und Sedativa.
Lohse, M.J.
In:
Arzneiverordnungs-Report 2020 : Aktuelle Daten, Kosten, Trends und Kommentare.
Springer, Berlin, Heidelberg, 571-582.
ISBN 978-3-662-62167-7
2020
Ophthalmika.
Lohse, M.J.
In:
Arzneiverordnungs-Report 2020 : Aktuelle Daten, Kosten, Trends und Kommentare.
Springer, Berlin, Heidelberg, 733-758.
ISBN 978-3-662-62168-4
2020
Psychopharmaka.
Lohse, M.J.
In:
Arzneiverordnungs-Report 2020 : Aktuelle Daten, Kosten, Trends und Kommentare.
Springer, Berlin, Heidelberg, 781-814.
ISBN 978-3-662-62168-4
2020
The serotonin-free brain: behavioral consequences of Tph2 deficiency in animal models.
Mosienko, V., Bader, M. and Alenina, N.
In:
Handbook of the Behavioral Neurobiology of Serotonin.
Handbook of Behavioral Neuroscience, 31
.
Elsevier, London et al., 601-607.
ISBN 978-0-444-64125-0
2020
Chloride transport across the lysosomal membrane.
Saha, S., Blessing, A. and Jentsch, T.J.
In:
Ion and Molecule Transport in Lysosomes.
CRC Press, Boca Raton, 19-44.
ISBN 9781351361132
2020
Cl(-) channels and Cl(-)/H(+) exchangers.
Ullrich, F. and Jentsch, T.J.
In:
Encyclopedia of Molecular Pharmacology.
Springer, Cham, 1-8.
ISBN 978-3-030-21573-6
2020
A-kinase anchoring proteins (AKAPs).
Walker-Gray, R. and Klussmann, E.
In:
Encyclopedia of Molecular Pharmacology.
Springer, Cham, 1-7.
ISBN 978-3-030-21573-6
2020
Conference or Workshop Item
SynergyNet: a fusion framework for multiple sclerosis brain MRI segmentation with local refinement.
Vang, Y.S., Cao, Y., Chang, P.D., Chow, D.S., Brandt, A.U., Paul, F., Scheel, M. and Xie, X.
In: 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), 3-7 Apr 2020, Iowa City, IA, USA.
22 May 2020
Book
Computational genomics with R.
Akalin, A.
Chapman and Hall/CRC Computational Biology Series
.
CRC Press LLC, Milton.
ISBN 9781498781855
2020
Review
Single-cell and spatial transcriptomics approaches of the bone marrow microenvironment.
Al-Sabah, J., Baccin, C. and Haas, S.
Current Opinion in Oncology 32
(2): 146-153.
1 March 2020
Novel basic science insights to improve the management of heart failure: review of the working group on cellular and molecular biology of the heart of the italian society of cardiology.
Ameri, P., Schiattarella, G.G., Crotti, L., Torchio, M., Bertero, E., Rodolico, D., Forte, M., Di Mauro, V., Paolillo, R., Chimenti, C., Torella, D., Catalucci, D., Sciarretta, S., Basso, C., Indolfi, C. and Perrino, C.
International Journal of Molecular Sciences 21
(4): 1192.
11 February 2020
Order and disorder: abnormal 3D chromatin organization in human disease.
Anania, C. and Lupianez, D.G.
Briefings in Functional Genomics 19
(2): 128-138.
March 2020
Pain in NMOSD and MOGAD: a systematic literature review of pathophysiology, symptoms, and current treatment strategies.
Asseyer, S., Cooper, G. and Paul, F.
Frontiers in Neurology 11
: 778.
21 August 2020
Inhibition of serotonin synthesis: a novel therapeutic paradigm.
Bader, M.
Pharmacology & Therapeutics 205
: 107423.
January 2020
The positional logic of sensory-motor reflex circuit assembly.
Balaskas, N., Ng, D. and Zampieri, N.
Neuroscience 450
: 142-150.
1 December 2020
Consensus-based technical recommendations for clinical translation of renal BOLD MRI.
Bane, O., Mendichovszky, I.A., Milani, B., Dekkers, I.A., Deux, J.F., Eckerbom, P., Grenier, N., Hall, M., Inoue, T., Laustsen, C., Lerman, L., Liu, C., Morrell, G., Pedersen, M., Pruijm, M., Sadowski, E., Seeliger, E., Sharma, K., Thoeny, H., Vermathen, P., Wang, Z., Serafin, Z., Zhang, J., Francis, S., Sourbron, S., Pohlmann, A., Fain, S. and Prasad, P.
Magnetic Resonance Materials in Physics Biology and Medicine 33
: 199-215.
February 2020
Analysing central metabolism in ultra-high resolution: at the crossroads of carbon and nitrogen.
Bayram, S., Fürst, S., Forbes, M. and Kempa, S.
Molecular Metabolism 33
: 38-47.
19 March 2020
Computational approaches from polymer physics to investigate chromatin folding.
Bianco, S., Chiariello, A.M., Conte, M., Esposito, A., Fiorillo, L., Musella, F. and Nicodemi, M.
Current Opinion in Cell Biology 64
: 10-17.
June 2020
Untangling the conformational polymorphism of disordered proteins associated with neurodegeneration at the single-molecule level.
Birol, M. and Melo, A.M.
Frontiers in Molecular Neuroscience 12
: 309.
10 January 2020
Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB).
Blois, S.M., Verlohren, S., Wu, G., Clark, G., Dell, A., Haslam, S.M. and Barrientos, G.
Seminars in Immunopathology 42
(4): 469-486.
August 2020
Functional roles of Grainyhead-like transcription factors in renal development and disease.
Boivin, F.J. and Schmidt-Ott, K.M.
Pediatric Nephrology 35
(2): 181-190.
February 2020
Cardiovascular disease in women: insights from magnetic resonance imaging.
Bucciarelli-Ducci, C., Ostenfeld, E., Baldassarre, L.A., Ferreira, V.M., Frank, L., Kallianos, K., Raman, S.V., Srichai, M.B., McAlindon, E., Mavrogeni, S., Ntusi, N.A.B., Schulz-Menger, J., Valente, A.M. and Ordovas, K.G.
Journal of Cardiovascular Magnetic Resonance 22
(1): 71.
28 September 2020
mRNAs, proteins and the emerging principles of gene expression control.
Buccitelli, C. and Selbach, M.
Nature Reviews Genetics 21
(10): 630-644.
October 2020
Decoding and targeting the molecular basis of MACC1-driven metastatic spread: lessons from big data mining and clinical-experimental approaches.
Budczies, J., Kluck, K., Walther, W. and Stein, U.
Seminars in Cancer Biology 60
: 365-379.
February 2020
Peripheral mechanisms of arthritic pain: a proposal to leverage large animals for in vitro studies.
Chakrabarti, S., Ai, M., Henson, F.M.D. and Smith, E.S.J.
Neurobiology of Pain 8
: 100051.
28 August 2020
Emerging drugs for the treatment of neuromyelitis optica.
Duchow, A., Chien, C., Paul, F. and Bellmann-Strobl, J.
Expert Opinion on Emerging Drugs 25
(3): 285-297.
September 2020
Current and emerging biologics for the treatment of neuromyelitis optica spectrum disorders.
Duchow, A., Paul, F. and Bellmann-Strobl, J.
Expert Opinion on Biological Therapy 20
(9): 1061-1072.
September 2020
Macrophage Cell-Cell Interactions Promoting HIV-1 Infection.
Dupont, M. and Sattentau, Q.J.
Viruses 12
(5): 492.
28 April 2020
Identifying progression in multiple sclerosis: new perspectives.
Filippi, M., Preziosa, P., Langdon, D., Lassmann, H., Paul, F., Rovira, À., Schoonheim, M.M., Solari, A., Stankoff, B. and Rocca, M.A.
Annals of Neurology 88
(3): 438-452.
September 2020
Notch1 in cancer therapy: possible clinical implications and challenges.
Gharaibeh, L., Elmadany, N., Alwosaibai, K. and Alshaer, W.
Molecular Pharmacology 98
(5): 559-576.
1 November 2020
Bradykinin B2 receptor signaling increases glucose uptake and oxidation: evidence and open questions.
Gregnani, M.F., Hungaro, T.G., Martins-Silva, L., Bader, M. and Araujo, R.C.
Frontiers in Pharmacology 11
: 1162.
4 August 2020
Sarcoma treatment in the era of molecular medicine.
Grünewald, T.G.P., Alonso, M., Avnet, S., Banito, A., Burdach, S., Cidre-Aranaz, F., Di Pompo, G., Distel, M., Dorado-Garcia, H., Garcia-Castro, J., González-González, L., Grigoriadis, A.E., Kasan, M., Koelsche, C., Krumbholz, M., Lecanda, F., Lemma, S., Longo, D.L., Madrigal-Esquivel, C., Morales-Molina, Á., Musa, J., Ohmura, S., Ory, B., Pereira-Silva, M., Perut, F., Rodriguez, R., Seeling, C., Al Shaaili, N., Shaabani, S., Shiavone, K., Sinha, S., Tomazou, E.M., Trautmann, M., Vela, M., Versleijen-Jonkers, Y.M.H., Visgauss, J., Zalacain, M., Schober, S.J., Lissat, A., English, W.R., Baldini, Ni. and Heymann, D.
EMBO Molecular Medicine 12
: e11131.
6 November 2020
Hematopoietic stem cells in health and disease - insights from single-cell multi-omic approaches.
Haas, S.
Current Stem Cell Reports 6
(3): 67-76.
September 2020
Karzinogenese: Big Bang oder kontinuierliche Evolution?
Haase, K. and Schwarz, R.F.
BIOspektrum 26
(7): 718-720.
November 2020
The role of the gut microbiota and microbial metabolites in neuroinflammation.
Haase, S., Wilck, N., Haghikia, A., Gold, R., Mueller, D.N. and Linker, R.A.
European Journal of Immunology 50
(12): 1863-1870.
December 2020
Microbe-driven genotoxicity in gastrointestinal carcinogenesis.
Hartl, K. and Sigal, M.
International Journal of Molecular Sciences 21
(20): 7439.
2 October 2020
Symmetry in nucleic-acid double helices.
Heinemann, U. and Roske, Y.
Symmetry 12
(5): 737.
5 May 2020
Left ventricular dysfunction in heart failure with preserved ejection fraction-molecular mechanisms and impact on right ventricular function.
Heinzel, F.R., Hegemann, N., Hohendanner, F., Primessnig, U., Grune, J., Blaschke, F., de Boer, R.A., Pieske, B., Schiattarella, G.G. and Kuebler, W.M.
Cardiovascular Diagnosis and Therapy 10
(5): 1541-1560.
October 2020
Epidemiology of neuromyelitis optica spectrum disorder and its prevalence and incidence worldwide.
Hor, J.Y., Asgari, N., Nakashima, I., Broadley, S.A., Leite, M.I., Kissani, N., Jacob, A., Marignier, R., Weinshenker, B.G., Paul, F., Pittock, S.J., Palace, J., Wingerchuk, D.M., Behne, J.M., Yeaman, M.R. and Fujihara, K.
Frontiers in Neurology 11
: 501.
26 June 2020
The dual role of serotonin in colorectal cancer.
Kannen, V., Bader, M., Sakita, J.Y., Uyemura, S.A. and Squire, J.A.
Trends in Endocrinology and Metabolism 31
(8): 611-625.
August 2020
Methods for mapping 3D chromosome architecture.
Kempfer, R. and Pombo, A.
Nature Reviews Genetics 21
(4): 207-226.
April 2020
Treatment and mortality of hemophagocytic lymphohistiocytosis in adult critically ill patients: a systematic review with pooled analysis.
Knaak, C., Schuster, F.S., Nyvlt, P., Spies, C., Feinkohl, I., Beutel, G., Schenk, T., La Rosée, P., Janka, G., Brunkhorst, F.M., Keh, D. and Lachmann, G.
Critical Care Medicine 48
(11): e1137-e1146.
November 2020
Small ones to fight a big problem-intervention of cancer metastasis by small molecules.
Kobelt, D., Dahlmann, M., Dumbani, M., Güllü, N., Kortüm, B., Vílchez, M.E.A., Stein, U. and Walther, W.
Cancers 12
(6): 1454.
3 June 2020
Visualizing the central nervous system: imaging tools for multiple sclerosis and neuromyelitis optica spectrum disorders.
Kuchling, J. and Paul, F.
Frontiers in Neurology 11
: 450.
17 June 2020
Claudins in the renal collecting duct.
Leiz, J. and Schmidt-Ott, K.M.
International Journal of Molecular Sciences 21
(1): 221.
2020
William D. Willis, Jr, MD, PhD Memorial Lecture: the evolutionary history of nerve growth factor and nociception.
Lewin, G.R.
Pain 161
(9 Suppl 1): S36-S47.
September 2020
Molecular genetics of human hypertension.
Luft, F.C.
Current Opinion in Cardiology 35
(3): 249-257.
May 2020
The German stem cell network GSCN - a nationwide network with many tasks.
Mahler, S. and Besser, D.
Stem Cell Research 42
: 101672.
January 2020
VPS10P domain receptors: sorting out brain health and disease.
Malik, A.R. and Willnow, T.E.
Trends in Neurosciences 43
(11): 870-885.
November 2020
The ESC 2019 CCS guidelines: have we left our patients and scientific evidence behind?
Manolis, A.J., Kallistratos, M.S., Poulimenos, L.Ε., Ambrosio, G., Dechend, R., Lopez-Sendon, J., Rosano, G. and Collins, P.
European Journal of Internal Medicine 72
: 5-8.
February 2020
Neurobiology of glycine transporters: from molecules to behavior.
Marques, B.L., Oliveira-Lima, O.C., Carvalho, G.A., de Almeida Chiarelli, R., Ribeiro, R.I., Parreira, R.C., da Madeira Freitas, E.M., Resende, R.R., Klempin, F., Ulrich, H., Gomez, R.S. and Pinto, M.C.X.
Neuroscience and Biobehavioral Reviews 118
: 97-110.
November 2020
Tackling mitochondrial diversity in brain function: from animal models to human brain organoids.
Menacho, C. and Prigione, A.
International Journal of Biochemistry and Cell Biology 123
: 105760.
June 2020
Angiogenesis in lymph nodes is a critical regulator of immune response and lymphoma growth.
Menzel, L., Höpken, U.E. and Rehm, A.
Frontiers in Immunology 11
: 591741.
3 December 2020
Peptide-based interaction proteomics.
Meyer, K. and Selbach, M.
Molecular & Cellular Proteomics 19
(7): 1070-1075.
July 2020
Sodium handling and interaction in numerous organs.
Minegishi, S., Luft, F.C., Titze, J. and Kitada, K.
American Journal of Hypertension 33
(8): 687-694.
August 2020
Accelerating drug development for neuroblastoma: summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma.
Moreno, L., Barone, G., DuBois, S.G., Molenaar, J., Fischer, M., Schulte, J., Eggert, A., Schleiermacher, G., Speleman, F., Chesler, L., Geoerger, B., Hogarty, M.D., Irwin, M.S., Bird, N., Blanchard, G.B., Buckland, S., Caron, H., Davis, S., De Wilde, B., Deubzer, H.E., Dolman, E., Eilers, M., George, R.E., George, S., Jaroslav, Š., Maris, J.M., Marshall, L., Merchant, M., Mortimer, P., Owens, C., Philpott, A., Poon, E., Shay, J.W., Tonelli, R., Valteau-Couanet, D., Vassal, G., Park, J.R. and Pearson, A.D.J.
European Journal of Cancer 136
: 52-68.
September 2020
Probing renal blood volume with magnetic resonance imaging.
Niendorf, T., Seeliger, E., Cantow, K., Flemming, B., Waiczies, S. and Pohlmann, A.
Acta Physiologica 228
(4): e13435.
April 2020
Salt and cardiovascular disease: insufficient evidence to recommend low sodium intake.
O'Donnell, M., Mente, A., Alderman, M.H., Brady, A.J.B., Diaz, R., Gupta, R., López-Jaramillo, P., Luft, F.C., Lüscher, T.F., Mancia, G., Mann, J.F.E., McCarron, D., McKee, M., Messerli, F.H., Moore, L.L., Narula, J., Oparil, S., Packer, M., Prabhakaran, D., Schutte, A., Sliwa, K., Staessen, J.A., Yancy, C. and Yusuf, S.
European Heart Journal 41
(35): 3363-3373.
14 September 2020
New aspects in cardiac L-type Ca(2+) channel regulation.
Pallien, T. and Klussmann, E.
Biochemical Society Transactions 48
(1): 39-49.
February 2020
eATP/P2X7R axis: an orchestrated pathway triggering inflammasome activation in muscle diseases.
Panicucci, C., Raffaghello, L., Bruzzone, S., Baratto, S., Principi, E., Minetti, C., Gazzerro, E. and Bruno, C.
International Journal of Molecular Sciences 21
(17): 5963.
19 August 2020
Selective androgen receptor modulators (SARMs) as pharmacological treatment for muscle wasting in ongoing clinical trials.
Peixoto da Fonseca, G.W., Dworatzek, E., Ebner, N. and von Haehling, S.
Expert Opinion on Investigational Drugs 29
(8): 881-891.
August 2020
The (un)conscious mouse as a model for human brain functions: key principles of anesthesia and their impact on translational neuroimaging.
Reimann, H.M. and Niendorf, T.
Frontiers in Systems Neuroscience 14
: 8.
19 May 2020
Evolution of new proteins from translated sORFs in long non-coding RNAs.
Ruiz-Orera, J., Villanueva-Cañas, J.L. and Albà, M.M.
Experimental Cell Research 391
(1): 111940.
1 June 2020
Stimulation of soluble guanylyl cyclase (sGC) by riociguat attenuates heart failure and pathological cardiac remodelling.
Rüdebusch, J., Benkner, A., Nath, N., Fleuch, L., Kaderali, L., Grube, K., Klingel, K., Eckstein, G., Meitinger, T., Fielitz, J. and Felix, S.B.
British Journal of Pharmacology 179
(11): 2430-2442.
June 2020
Divergent transcription of the Nkx2-5 locus generates two enhancer RNAs with opposing functions.
Salamon, I., Serio, S., Bianco, S., Pagiatakis, C., Crasto, S., Chiariello, A.M., Conte, M., Cattaneo, P., Fiorillo, L., Felicetta, A., di Pasquale, E., Kunderfranco, P., Nicodemi, M., Papait, R. and Condorelli, G.
iScience 23
(9): 101539.
25 September 2020
ASH highlights 2019: "aggressive B-cell lymphoma".
Schmitt, C.A.
memo: Magazine of European Medical Oncology 13
(3): 266-269.
20 May 2020
Nonclinical data supporting orphan medicinal product designations in the area of rare infectious diseases.
Sheean, M.E., Malikova, E., Duarte, D., Capovilla, G., Fregonese, L., Hofer, M., Magrelli, A., Mariz, S., Mendez-Hermida, F., Nistico, R., Leest, T., Sipsas, N.V., Tsigkos, S., Vitezic, D., Larsson, K., Sepodes, B. and Stoyanova-Beninska, V.
Drug Discovery Today 25
(2): 274-291.
February 2020
Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms.
Smith, E.S.J., Park, T.J. and Lewin, G.R.
Journal of Comparative Physiology A 206
(3): 313-325.
May 2020
The European Research Network on Signal Transduction (ERNEST): toward a multidimensional holistic understanding of G protein-coupled receptor signaling.
Sommer, M.E., Selent, J., Carlsson, J., De Graaf, C., Gloriam, D.E., Keseru, G.M., Kosloff, M., Mordalski, S., Rizk, A., Rosenkilde, M.M., Sotelo, E., Tiemann, J.K.S., Tobin, A., Vardjan, N., Waldhoer, M. and Kolb, P.
ACS Pharmacology & Translational Science 3
(2): 361-370.
10 April 2020
Evolving methodologies and concepts in 4D nucleome research.
Sparks, T.M., Harabula, I. and Pombo, A.
Current Opinion in Cell Biology 64
: 105-111.
June 2020
Tara Oceans: towards global ocean ecosystems biology.
Sunagawa, S., Acinas, S.G., Bork, P., Bowler, C., Eveillard, D., Gorsky, G., Guidi, L., Iudicone, D., Karsenti, E., Lombard, F., Ogata, H., Pesant, S., Sullivan, M.B., Wincker, P. and de Vargas, C.
Nature Reviews Microbiology 18
(8): 428-445.
August 2020
Keeping the proportions of protein complex components in check.
Taggart, J.C., Zauber, H., Selbach, M., Li, G.W. and McShane, E.
Cell Systems 10
(2): 125-132.
26 February 2020
Up and down states and memory consolidation across somatosensory, entorhinal, and hippocampal cortices.
Tukker, J.J., Beed, P., Schmitz, D., Larkum, M.E. and Sachdev, R.N.S.
Frontiers in Systems Neuroscience 14
: 22.
8 May 2020
Single-cell analyses of aging, inflammation and senescence.
Uyar, B., Palmer, D., Kowald, A., Escobar, H.M., Barrantes, I., Möller, S., Akalin, A. and Fuellen, G.
Ageing Research Reviews 64
: 101156.
December 2020
The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review.
Van Paemel, R., Vlug, R., De Preter, K., Van Roy, N., Speleman, F., Willems, L., Lammens, T., Laureys, G., Schleiermacher, G., Tytgat, G.A.M., Astrahantseff, K., Deubzer, H. and De Wilde, B.
European Journal of Pediatrics 179
: 191-202.
February 2020
Diversity within species: interpreting strains in microbiomes.
Van Rossum, T., Ferretti, P., Maistrenko, O.M. and Bork, P.
Nature Reviews Microbiology 18
: 491-506.
September 2020
Ubiquitination and ubiquitin-like modifications in multiple myeloma: biology and therapy.
Wirth, M., Schick, M., Keller, U. and Krönke, J.
Cancers 12
(12): 3764.
14 December 2020
Responses of gastric epithelial stem cells and their niche to Helicobacter pylori infection.
Wizenty, J., Tacke, F. and Sigal, M.
Annals of Translational Medicine 8
(8): 568.
April 2020
Conversion of germ cells to somatic cell types in C. elegans.
ul Fatima, N. and Tursun, B.
Journal of Developmental Biology 8
(4): 24.
December 2020
Conservation of a core neurite transcriptome across neuronal types and species.
von Kügelgen, N. and Chekulaeva, M.
Wiley Interdisciplinary Reviews: RNA 11
(4): e1590.
July 2020
Letter
Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML).
Agrawal, M., Schwarz, P., Giaimo, B.D., Bedzhov, I., Corbacioglu, A., Weber, D., Gaidzik, V.I., Jahn, N., Rücker, F.G., Schroeder, T., Kindler, T., Wattad, M., Götze, K., Lübbert, M., Salwender, H., Ringhoffer, M., Lange, E., Koller, E., Thol, F., Heuser, M., Ganser, A., Bullinger, L., Paschka, P., Döhner, H., Geiger, H., Borggrefe, T., Döhner, K. and Oswald, F.
Leukemia 34
(2): 630-634.
February 2020
Clonal hematopoiesis in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis.
Arends, C.M., Weiss, M., Christen, F., Eulenberg-Gustavus, C., Rousselle, A., Kettritz, R., Eckardt, K.U., Chan, W., Hoyer, K., Frick, M., Bullinger, L., Bieringer, M., Schreiber, A. and Damm, F.
Haematologica 105
(6): e264-e267.
June 2020
Phenotype consensus is required to enable large-scale genetic consortium studies of food allergy.
Asai, Y., Martino, D., Eiwegger, T., Nadeau, K., Koppelman, G.H., Clarke, A.E., Lee, Y.A., Chan, E.S., Simons, E., Laprise, C., Mazer, B., Marenholz, I., Royce, D., Elliott, S.J., Hampson, C., Gerdts, J., Eslami, A., Soller, L., Hui, J., Azad, M., Sandford, A. and Daley, D.
Allergy 75
(9): 2383-2387.
23 April 2020
Myocardial evaluation of post-preeclamptic women by CMR: is early risk stratification possible?
Birukov, A., Wiesemann, S., Golic, M., Balogh, A., Marko, L., Rakova, N., Wilck, N., Blaszczyk, E., Lim, C., Weiss, S., Kräker, K., Haase, N., Frolova, A., Jørgensen, J.S., Daub, S., Mueller, D.N., Herse, F., Schulz-Menger, J. and Dechend, R.
JACC: Cardiovascular Imaging 13
(5): 1291-1293.
May 2020
Aggressive multiple sclerosis - a matter of measurement and timing.
Ellenberger, D., Flachenecker, P., Fneish, F., Frahm, N., Hellwig, K., Paul, F., Stahmann, A., Warnke, C., Rommer, P.S. and Zettl, U.K.
Brain 143
(11): e97.
November 2020
Frequency of autoimmune disorders and autoantibodies in European patients with neuromyelitis optica spectrum disorders.
Gkaniatsou, T., Papadopoulou, A., Paul, F., Brandt, A.U. and Oertel, F.C.
Acta Neurologica Belgica 120
(1): 223-225.
February 2020
The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Grasedieck, S., Ruess, C., Krowiorz, K., Lux, S., Pochert, N., Schwarzer, A., Klusmann, J.H., Jongen-Lavrencic, M., Herold, T., Bullinger, L., Pollack, J.R., Rouhi, A. and Kuchenbauer, F.
Haematologica 105
(9): e448-e453.
September 2020
CLIJ: GPU-accelerated image processing for everyone.
Haase, R., Royer, L.A., Steinbach, P., Schmidt, D., Dibrov, A., Schmidt, U., Weigert, M., Maghelli, N., Tomancak, P., Jug, F. and Myers, E.W.
Nature Methods 17
(1): 5-6.
January 2020
Evolution of pulmonary hypertension during severe sustained hypoxia.
Hoffmann, F., Limper, U., Zaha, V.G., Reuter, H., Zange, L., Schulz-Menger, J., Hein, M., Baldus, S., Levine, B.D., Jordan, J. and Tank, J.
Circulation 141
(18): 1504-1506.
5 May 2020
Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia.
In't Hout, F.E.M., Gerritsen, M., Bullinger, L., Van der Reijden, B.A., Huls, G., Vellenga, E. and Jansen, J.H.
Haematologica 105
(9): e454-457.
1 September 2020
A randomized open label phase-II clinical trial with or without infusion of plasma from subjects after convalescence of SARS-CoV-2 infection in high-risk patients with confirmed severe SARS-CoV-2 disease (RECOVER): a structured summary of a study protocol for a randomised controlled trial.
Janssen, M., Schäkel, U., Djuka Fokou, C., Krisam, J., Stermann, J., Kriegsmann, K., Haberbosch, I., Novotny, J.P., Weber, S., Vehreschild, M., Bornhäuser, M., Bullinger, L., Schmitt, M., Liebregts, T., Dreger, P., Lorenz, H.M., Plaszczyca, A., Bartenschlager, R., Müller, B., Kräusslich, H.G., Halama, N., Jäger, D., Schlenk, R.F., Leo, A., Meuer, S., Weigand, M.A., Motsch, J., Merle, U., Denkinger, C.M. and Müller-Tidow, C.
Trials 21
(1): 828.
6 October 2020
Caplacizumab: frequent local skin reactions.
Kaufeld, J., Brinkkoetter, P.T., Schreiber, A., Jabs, W.J., Bieringer, M., Bruck, H., Menne, J. and Völker, L.A.
Annals of Hematology 100
(12): 3051-3052.
December 2020
Laying out the evidence for the persistence of neurogenesis in the adult human hippocampus.
Kronenberg, G. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 270
(4): 497-498.
June 2020
Fibroblasts from atopic dermatitis patients trigger inflammatory processes and hyperproliferation in human skin equivalents.
Löwa, A., Graff, P., Kaessmeyer, S. and Hedtrich, S.
Journal of the European Academy of Dermatology and Venereology 34
(6): e262-e265.
June 2020
Transmission of chromosomally integrated human herpes virus-6A via haploidentical stem cell transplantation poses a risk for virus reactivation and associated complications.
Oevermann, L., Zimmermann, C., Voigt, S., Künkele, A., Lobitz, S., Eggert, A., Schulte, J.H., Kaufer, B.B. and Deubzer, H.E.
Bone Marrow Transplantation 55
(1): 260-264.
January 2020
Safety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part phase Ib/II study.
Rambaldi, A., Iurlo, A., Vannucchi, A.M., Noble, R., von Bubnoff, N., Guarini, A., Martino, B., Pezzutto, A., Carli, G., De Muro, M., Luciani, S., McMullin, M.F., Cambier, N., Marolleau, J.P., Mesa, R.A., Tibes, R., Pancrazzi, A., Gesullo, F., Bettica, P., Manzoni, S. and Di Tollo, S.
Leukemia 34
(8): 2234-2237.
August 2020
The (pro)renin receptor: what's in a name?
Simons, M., Bader, M. and Müller, D.N.
Nature Reviews Nephrology 16
(5): 304.
May 2020
Proteomic analysis reveals upregulation of ACE2, the putative SARS-CoV-2 receptor in pressure- but not volume-overloaded human hearts.
Stegbauer, J., Kraus, M., Nordmeyer, S., Kirchner, M., Ziehm, M., Dommisch, H., Kelle, S., Kelm, M., Baczko, I., Landmesser, U., Tschope, C., Knosalla, C., Falcke, M., Schapranow, M.P., Regitz-Zagrosek, V., Mertins, P. and Kuehne, T.
Hypertension 76
(6): e41-e43.
December 2020
Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis.
Thyssen, J.P., Ahluwalia, T.S., Paternoster, L., Ballardini, N., Bergström, A., Melén, E., Chawes, B., Stokholm, J., Hourihane, J.O., O'Sullivan, D.M., Bager, P., Maelbye, M., Bustamante, M., Torrent, M., Esplugues, A., Duijts, L., Hu, C., Elbert, N.J., Pasmans, S.G.M.A., Nijsten, T.E C., von Berg, A., Standl, M., Schikowski, T., Herberth, G., Heinrich, J., Lee, Y.A., Marenholz, I., Lau, S., Curtin, J.A., Simpson, A., Custovic, A., Pennell, C.E., Wang, C.A., Holt, P.G., Bisgaard, H. and Bønnelykke, K.
Allergy 75
(6): 1481-1485.
June 2020
Interruption of the CXCL13/CXCR5 chemokine axis enhances plasma IgM levels and attenuates atherosclerosis development.
van der Vorst, E.P.C., Daissormont, I., Aslani, M., Seijkens, T., Wijnands, E., Lutgens, E., Duchene, J., Santovito, D., Döring, Y., Halvorsen, B., Aukrust, P., Weber, C., Höpken, U.E. and Biessen, E.A.L.
Thrombosis and Haemostasis 120
(2): 344-347.
February 2020
Editorial
Das Fundament ist gelegt - für verbesserte Vorbeugung und Früherkennung der großen Volkskrankheiten [The foundation has been laid - for improved prevention and early detection of major common diseases].
Ahrens, W., Pigeot, I. and Pischon, T.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(4): 373-375.
April 2020
Was macht krank, was hält uns gesund? [What makes us sick, what keeps us healthy?].
Ahrens, W., Pigeot, I. and Pischon, T.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63
(3): 251-253.
March 2020
Spatial heterogeneity in molecular brightness.
Annibale, P. and Lohse, M.J.
Nature Methods 17
(3): 273-275.
March 2020
ACE2, a multifunctional protein - from cardiovascular regulation to COVID-19.
Bader, M., Turner, A.J. and Alenina, N.
Clinical Science 134
(23): 3229-3232.
11 December 2020
Blood pressure changes correlate with short-chain fatty acid production potential shifts under a synbiotic intervention.
Bartolomaeus, H., Avery, E.G., Bartolomaeus, T.U.P., Kozhakhmetov, S., Zhumadilov, Z., Müller, D.N., Wilck, N., Kushugulova, A. and Forslund, S.K.
Cardiovascular Research 116
(7): 1252-1253.
June 2020
Hitchhiker's guide to microbiome studies.
Bartolomaeus, T.U.P. and Forslund, S.K.
Cardiovascular Research 116
(3): e44-e47.
1 March 2020
Fine-tuning stemness.
Borsa, M. and Simon, A.K.
Science 369
(6502): 373-374.
24 July 2020
Imagine physiology without imaging.
Cantow, K., Hummel, L., Flemming, B., Waiczies, S., Niendorf, T. and Seeliger, E.
Acta Physiologica 230
(3): e13549.
November 2020
Endothelial cells don't waste: endothelial-derived lactate boosts muscle regeneration.
Castro, M., Andrade, J. and Potente, M.
Developmental Cell 54
(2): 137-139.
20 July 2020
What is extrachromosomal circular DNA and what does it do?
Chiu, R.W.K., Dutta, A., Henssen, A.G., Lo, Y.M.D., Mischel, P. and Regenberg, B.
Clinical Chemistry 66
(6): 754-759.
June 2020
N2 year in review.
Dalmau, J., Dalakas, M.C., Kolson, D.L., Paul, F. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 7
(1): e644.
January 2020
Melanozytäre Naevi der Haut bei einem Neugeborenen [Dermal melanocytic nevi in a newborn].
Endres, S., Wilke, M., Höche, A., Gertz, A., Schubert, R., Deubzer, H., Eggert, A., Rossi, R. and Schlembach, D.
Gynäkologe 53
(8): 554-556.
August 2020
Feeding diastolic dysfunction: is it a bug?
Esposito, G. and Schiattarella, G.G.
Journal of Cardiac Failure 26
(8): 703-704.
August 2020
Editorial: Renal hypertension at the crossroads: theoretical, experimental and clinical aspects.
Gollasch, M. and Hoyer, J.
Frontiers in Medicine 7
: 49.
19 February 2020
So läuft es bei uns am Max-Delbrück-Centrum für Molekulare Medizin in der Helmhotz-Gemeinschaft.
Graßmann, H.
DUZ 20
(3): 62.
20 March 2020
A survey of travel behaviour among scientists in Germany and the potential for change.
Haage, V.
eLife 9
: e56765.
28 May 2020
Covid-19, ACE2, and the kidney.
Hardenberg, J.H. and Luft, F.C.
Acta Physiologica 230
(1): e13539.
September 2020
"Designer cytokines" targeting the tumor vasculature - think global and act local.
Kammertoens, T., Kemna, J. and Leisegang, M.
EMBO Molecular Medicine 12
(2): e11801.
7 February 2020
Arterial elementary calcium signaling in aging.
Kassmann, M., Fan, G. and Gollasch, M.
Aging 12
(24): 24476-24478.
31 December 2020
Did you know? Fluid-and-electrolyte replacement and the uncertainty principle.
Luft, F.C.
Acta Physiologica 230
(4): e13511.
December 2020
Did you know? Why is essential hypertension essential - or is it?
Luft, F.C.
Acta Physiologica 229
(3): e13469.
July 2020
Epigenetic chaperoning of aging.
Müthel, S. and Tursun, B.
Aging 12
(2): 1044-1046.
31 January 2020
Google maps for tissues: multiscale imaging of biological systems and disease.
Niendorf, T., Frydman, L., Neeman, M. and Seeliger, E.
Acta Physiologica 228
(2): e13392.
February 2020
The impact of the COVID-19 pandemic on self-reported health.
Peters, A., Rospleszcz, S., Greiser, K.H., Dallavalle, M., Karch, A., Mikolajczyk, R., Krause, G., Castell, S., Nieters, A., Kraft, D., Wolff, R., Stübs, G., Lang, O., Panreck, L., Rietschel, M., Rujescu, D., Dragano, N., Schmidt, B., Becher, H., Brenner, H., Damms-Machado, A., Fischer, B., Franzke, C.W., Gastell, S., Günther, K., Hermes, A., Holleczek, B., Jaeschke, L., Jöckel, K.H., Kaaks, R., Keil, T., Kemmling, Y., Kluttig, A., Kuß, O., Legath, N., Leitzmann, M., Lieb, W., Loeffler, M., Meinke-Franze, C., Michels, K.B., Obi, N., Pischon, T., Schikowski, T., Schulze, M.B., Stang, A., Thierry, S., Völzke, H., Willlich, S.N., Wirkner, K., Wolf, K., Zeeb, H. and Berger, K.
Deutsches Aerzteblatt International 117
: 861-867.
11 December 2020
Studying human glial cells: where are we today?
Ransom, B.R. and Kettenmann, H.
Glia 68
(4): 683-684.
April 2020
A CD205-directed antibody drug conjugate - lymphoma precision oncology or sophisticated chemotherapy?
Rieke, D.T. and Keller, U.
Haematologica 105
(11): 2504-2506.
1 November 2020
Editorial: Modulation of human immune parameters by anticancer therapies.
Sack, U., Tarnok, A., Preijers, F., Köhl, U. and Na, I.K.
Frontiers in Immunology 11
: 621556.
2 December 2020
Can HFpEF and HFrEF coexist?
Schiattarella, G.G., Tong, D. and Hill, J.A.
Circulation 141
(9): 709-711.
3 March 2020
Mix for regeneration: nephron replacement by transplanted cells.
Schmidt-Ott, K.M.
Journal of the American Society of Nephrology 31
(12): 2743-2745.
December 2020
Beth Levine 1960-2020.
Simon, A.K. and Mizushima, N.
Nature Cell Biology 22
(8): 909-910.
August 2020
COVID-19 pandemic and cardiac imaging: EACVI recommendations on precautions, indications, prioritization, and protection for patients and healthcare personnel.
Skulstad, H., Cosyns, B., Popescu, B.A., Galderisi, M., Di Salvo, G., Donal, E., Petersen, S., Gimelli, A., Haugaa, K.H., Muraru, D., Almeida, A.G., Schulz-Menger, J., Dweck, M.R., Pontone, G., Sade, L.E., Gerber, B., Maurovich-Horvat, P., Bharucha, T., Cameli, M., Magne, J., Westwood, M., Maurer, G. and Edvardsen, T.
European Heart Journal - Cardiovascular Imaging 21
(6): 592-598.
June 2020
Will postnatal renin-angiotensin system blockade improve long-term maternal cardiovascular health after preeclampsia?
Staff, A.C. and Dechend, R.
Hypertension 76
(6): 1704-1706.
December 2020
The role of AKAP12 in coordination of VEGF-induced endothelial cell motility.
Walker-Gray, R. and Klussmann, E.
Acta Physiologica 228
(1): e13359.
January 2020
Polyamines reverse immune senescence via the translational control of autophagy.
Zhang, H. and Simon, A.K.
Autophagy 16
(1): 181-182.
January 2020
Understanding neurodegenerative changes of the afferent visual pathway in MS.
Zimmermann, H.G. and Oertel, F.C.
Neurology Neuroimmunology & Neuroinflammation 7
(2): e667.
March 2020
Comment
Chromosomes phase transition to function.
Nicodemi, M. and Bianco, S.
Biophysical Journal 119
(4): 724-725.
18 August 2020
Preprint
Determinants of SARS-CoV-2 receptor gene expression in upper and lower airways.
Aliee, H., Massip, F., Qi, C., de Biase, M.S., van Nijnatten, J.L., Kersten, E.T.G., Kermani, N.Z., Khuder, B., Vonk, J.M., Vermeulen, R.C.H., Neighbors, M., Tew, G.W., Grimbaldeston, M., Ten Hacken, N.H.T., Hu, S., Guo, Y., Zhang, X., Sun, K., Hiemstra, P.S., Ponder, B.A., Makela, M.J., Malmstrom, K., Rintoul, R.C., Reyfman, P.A., Theis, F.J., Brandsma, C.A., Adcock, I., Timens, W., Xu, C.J., van den Berge, M., Schwarz, R.F., Koppelman, G.H., Nawijn, M.C. and Faiz, A.
medRxiv
: 2020.08.31.20169946.
2 September 2020
Co-activation of NF-κB and MYC renders cancer cells addicted to IL6 for survival and phenotypic stability.
Barbosa, R.R., Xu, A.Q., D'Andrea, D., Copley, F., Patel, H., Chakravarty, P., Clear, A., Calaminici, M., Janz, M., Zhang, B., Schmidt-Supprian, M., Wang, J., Gribben, J.G., Tooze, R., Fitzgibbon, J., Franzoso, G., Rajewsky, K. and Calado, D.P.
bioRxiv
: 2020.04.12.038414.
13 April 2020
CD40 provides immune privilege to the bone marrow hematopoietic niche.
Bassani, B., Gulino, A., Portararo, P., Botti, L., Cappetti, B., Chiodoni, C., Bolli, N., Ciciarello, M., Joehrens, K., Anagnostopoulos, I., Na, I.K., Curti, A., Tripodo, C., Colombo, M.P. and Sangaletti, S.
bioRxiv
: 2020.08.10.243691.
10 August 2020
Establishment of kidney cancer organoid cultures.
Bauer, D., Birchmeier, W. and Fendler, A.
Research Square
: rs.3.pex-911.
12 May 2020
LoopDetect: comprehensive feedback loop detection in ordinary differential equation models.
Baum, K. and Wolf, J.
bioRxiv
: 2020.11.15.383703.
17 November 2020
Myogenic vasoconstriction requires canonical Gq/11 signaling of the angiotensin II type 1a receptor in the murine vasculature.
Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y.M., Schleifenbaum, J., Bader, M., Welsh, D.G., Huang, Y. and Gollasch, M.
bioRxiv
: 2020.09.09.289280.
11 September 2020
HMGXB4 targets Sleeping Beauty transposition to vertebrate germinal stem sells.
Devaraj, A., Singh, M., Narayanavari, S., Yong, G., Wang, J., Wang, J., Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z., Grzela, D., Raskó, T., Selbach, M., Ivics, Z. and Izsvák, Z.
bioRxiv
: 2020.06.15.145656.
15 June 2020
Harnessing spatial homogeneity of neuroimaging data: patch individual filter layers for CNNs.
Eitel, F., Albrecht, J.P., Weygandt, M., Paul, F. and Ritter, K.
arXiv
: 2007.11899.
23 July 2020
Dissecting HSV-1-induced host shut-off at RNA level.
Friedel, C.C., Whisnant, A.W., Djakovic, L., Rutkowski, A.J., Friedl, M.S., Kluge, M., Williamson, J.C., Sai, S., Oliveira Vidal, R., Sauer, S., Hennig, T., Prusty, B., Lehner, P.J., Matheson, N.J., Erhard, F. and Dölken, L.
bioRxiv
: 2020.05.20.106039.
20 May 2020
Open Source ImmGen: network perspective on metabolic diversity among mononuclear phagocytes.
Gainullina, A., Huang, L.H., Todorov, H., Kim, K., Yng, L.S., Kent, A., Jia, B., Seddu, K., Krchma, K., Wu, J., Crozat, K., Tomasello, E., Narang, V., Dress, R., See, P., Scott, C., Gibbings, S., Bajpai, G., Desai, J.V., Maier, B., This, S., Wang, P., Aguilar, S.V., Poupel, L., Dussaud, S., Zhou, T.A., Angeli, V., Blander, J.M., Choi, K., Dalod, M., Dzhagalov, I., Gautier, E.L., Jakubzick, C., Lavine, K., Lionakis, M.S., Paidassi, H., Sieweke, M.H., Ginhoux, Fl., Guilliams, M., Benoist, C., Merad, M., Randolph, G.J., Sergushichev, A. and Artyomov, M.N.
bioRxiv
: 2020.07.15.204388.
16 July 2020
Mechanistic basis for motor-driven membrane constriction by dynamin.
Ganichkin, O., Vancraenenbroeck, R., Rosenblum, G., Hofmann, H., Mikhailov, A.S., Daumke, O. and Noel, J.K.
bioRxiv
: 2020.09.10.289546.
11 September 2020
Exploiting a PAX3-FOXO1-induced synthetic lethal ATR dependency for rhabdomyosarcoma therapy.
García, H.D., Bei, Y., von Stebut, J., Ibáñez, G., Imami, K., Gürgen, D., Rolff, J., Helmsauer, K., Timme, N., Bardinet, V., Chamorro González, R., MacArthur, I.C., Pusch, F.F., Chen, C.Y., Schulz, J., Wengner, A.M., Furth, C., Lala, B., Eggert, A., Seifert, G., Hundsoerfer, P., Kirchner, M., Mertins, P., Selbach, M., Lissat, A., Schulte, J.H., Haase, K., Scheer, M., Ortiz, M.V. and Henssen, A.G.
bioRxiv
: 2020.12.04.411413.
2020
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II at pro-differentiation genes.
Garipler, G., Lu, C., Morrissey, A., Lopez-Zepeda, L.S., Vidal, S.E., Aydin, B., Stadtfeld, M., Ohler, U., Mahony, S., Sanjana, N.E. and Mazzoni, E.O.
bioRxiv
: 2020.11.23.391771.
23 November 2020
Vascular cognitive impairment in the mouse reshapes visual, spatial network functional connectivity.
Hall, G.R., Boehm-Sturm, P., Dirnagl, U., Finke, C., Foddis, M., Harms, C., Koch, S.P., Kuchling, J., Madan, C.R., Mueller, S., Sassi, C., Sotiropoulos, S.N., Trueman, R.C., Wallis, M., Yildirim, F. and Farr, T.D.
bioRxiv
: 2020.11.04.366294.
5 November 2020
The mechanotransduction protein STOML3 is required for functional plasticity following peripheral nerve regeneration.
Haseleu, J., Walcher, J. and Lewin, G.R.
bioRxiv
: 2020.11.10.367748.
10 November 2020
VarFish - Collaborative and comprehensive variant analysis for diagnosis and research.
Holtgrewe, M., Stolpe, O., Nieminen, M., Mundlos, S., Knaus, A., Kornak, U., Seelow, D., Segebrecht, L., Spielmann, M., Fischer-Zirnsak, B., Boschann, F., Scholl, U., Ehmke, N. and Beule, D.
bioRxiv
: 2020.01.27.921965.
31 January 2020
Cdon mutation and fetal alcohol converge on nodal signaling in a gene-environment interaction model of holoprosencephaly.
Hong, M., Christ, A., Christa, A., Willnow, T.E. and Krauss, R.S.
bioRxiv
: 2020.04.30.070870.
1 May 2020
CTCF mediates dosage and sequence-context-dependent transcriptional insulation through formation of local chromatin domains.
Huang, H., Zhu, Q., Jussila, A., Han, Y., Bintu, B., Kern, C., Conte, M., Zhang, Y., Bianco, S., Chiariello, A.M., Yu, M., Hu, R., Juric, I., Hu, M., Nicodemi, M., Zhuang, X. and Ren, B.
bioRxiv
: 2020.07.07.192526.
8 July 2020
The CONDOR pipeline for simultaneous knockdown of multiple genes identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M., Díaz, C.F., Ofenbauer, A. and Tursun, B.
bioRxiv
: 2020.09.01.276972.
1 September 2020
Single cell RNA-sequencing-based analysis of CD4(+) T-cell subset-specific susceptibility to transcriptional modulation by HIV-1 latency-reversing agents.
Kazmierski, J., Postmus, D., Wyler, E., Fischer, C., Jansen, J., Meixenberger, K., Vitcetz, S.N., Sohn, M., Sauer, S., Bannert, N., Landthaler, M. and Goffinet, C.
bioRxiv
: 2020.05.04.075119.
5 May 2020
Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation.
Kim, M., Zhang, Y. and Birchmeier, C.
bioRxiv
: 2020.12.22.424062.
22 December 2020
Regional expression profiles of risk genes for depression are associated with brain activation patterns in emotion and reward tasks.
Komorowski, A., Vidal, R., Singh, A., Murgaš, M., Pena-Centeno, T., Gryglewski, G., Kasper, S., Wiltfang, J., Lanzenberger, R. and Goya-Maldonado, R.
bioRxiv
: 2020.06.27.175257.
27 June 2020
A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
Kreye, J., Reincke, S.M., Kornau, H.C., Sanchez-Sendin, E., Corman, V.M., Liu, H., Yuan, M., Wu, N.C., Zhu, X., Lee, C.C.D., Trimpert, J., Hoeltje, M., Dietert, K., Stoeffler, L., von Wardenburg, N., van Hoof, S., Homeyer, M.A., Hoffmann, J., Abdelgawad, A., Gruber, A.D., Bertzbach, L.D., Vladimirova, D., Li, L.Y., Barthel, P.C., Skriner, K., Hocke, A.C., Hippenstiel, S., Witzenrath, M., Suttorp, N., Kurth, F., Franke, C., Endres, M., Schmitz, D., Jeworowski, L.M., Richter, A., Schmidt, M.L., Schwarz, T., Mueller, M.A., Drosten, C., Wendisch, D., Sander, L.E., Osterrieder, N., Wilson, I.A. and Pruess, H.
bioRxiv
: 2020.08.15.252320.
16 August 2020
Deciphering the regulatory logic of a Drosophila enhancer through systematic sequence mutagenesis and quantitative image analysis.
Le Poul, Y., Xin, Y., Ling, L., Mühling, B., Jaenichen, R., Hörl, D., Bunk, D., Harz, H., Leonhardt, H., Wang, Y., Osipova, E., Museridze, M., Dharmadhikari, D., Murphy, E., Rohs, R., Preibisch, S., Prud'homme, B. and Gompel, N.
bioRxiv
: 2020.06.24.169748.
25 June 2020
Host genetic and environmental factors shape the human gut resistome.
Le Roy, C.I., Bowyer, R.C.E., Carr, V.R., Costeira, R., Castillo-Fernandez, J.E.R., Martin, T.C., Spector, T., Steves, C., Moyes, D., Forslund, S.K. and Bell, J.T.
bioRxiv
: 2020.05.18.092973.
20 May 2020
Morphine alleviates pain after heart cryoinjury in zebrafish without impeding regeneration.
Lelek, S., Simões, M., Hu, B., Alameldeen, A.M.A., Czajkowski, M.T., Meyer, A.M., Ferrara, F., Junker, J.P. and Panáková, D.
bioRxiv
: 2020.10.01.322560.
2 October 2020
Cells and gene expression programs in the adult human heart.
Litviňuková, M., Talavera-López, C., Maatz, H., Reichart, D., Worth, C.L., Lindberg, E.L., Kanda, M., Polanski, K., Fasouli, E.S., Samari, S., Roberts, K., Tuck, L., Heinig, M., DeLaughter, D.M., McDonough, B., Wakimoto, H., Gorham, J.M., Nadelmann, E.R., Mahbubani, K.T., Saeb-Parsy, K., Patone, G., Boyle, J.J., Zhang, H., Zhang, H., Viveiros, A., Oudit, G.Y., Bayraktar, O., Seidman, J.G., Seidman, C., Noseda, M., Hübner, N. and Teichmann, S.A.
bioRxiv
: 2020.04.03.024075.
10 April 2020
Mapping the unique and shared functions of oncogenic KRAS and RIT1 with proteome and transcriptome profiling.
Lo, A., Holmes, K., Mundt, F., Moorthi, S., Fung, I., Fereshetian, S., Watson, J., Carr, S.A., Mertins, P. and Berger, A.H.
bioRxiv
: 2020.04.10.030460.
11 April 2020
Olig3 acts as a master regulator of cerebellar development.
Lowenstein, E.D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A.E., Epifanova, E., Bladt, F., Isik, E.G., Jia, S., Tarabykin, V. and Hernandez-Miranda, L.R.
bioRxiv
: 2020.10.10.334615.
10 October 2020
Diverse chemotypes drive biased signaling by cannabinoid receptors.
Miljuš, T., Heydenreich, F.M., Gazzi, T., Kimbara, A., Rogers-Evans, M., Nettekoven, M., Zirwes, E., Osterwald, A., Rufer, A.C., Ullmer, C., Guba, W., Le Gouill, C., Fingerle, J., Nazaré, M., Grether, U., Bouvier, M. and Veprintsev, D.B.
bioRxiv
: 2020.11.09.375162.
10 November 2020
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells.
Muus, C., Luecken, M.D., Eraslan, G., Waghray, A., Heimberg, G., Sikkema, L., Kobayashi, Y., Vaishnav, E.D., Subramanian, A., Smilie, C., Jagadeesh, K., Thu Duong, E., Fiskin, E., Torlai Triglia, E., Ansari, M., Cai, P., Lin, B., Buchanan, J., Chen, S., Shu, J., Haber, A.L., Chung, H., Montoro, D.T., Adams, T., Aliee, H., Allon, S.J., Andrusivova, A.Z., Angelidis, I., Ashenberg, O., Bassler, K., Bécavin, C., Benhar, I., Bergenstråhle, J., Bergenstråhle, L., Bolt, L., Braun, E., Bui, L.T., Chaffin, M., Chichelnitskiy, E., Chiou, J., Conlon, T.M., Cuoco, M.S., Deprez, M., Fischer, D.S., Gillich, A., Gould, J., Guo, M., Gutierrez, A.J., Habermann, A.C., Harvey, T., He, P., Hou, X., Hu, L., Jaiswal, A., Jiang, P., Kapellos, T., Kuo, C.S., Larsson, L., Leney-Greene, M.A., Lim, K., Litviňuková, M., Lu, J., Ludwig, L.S., Luo, W., Maatz, H., Madissoon, E., Mamanova, L., Manakongtreecheep, K., Marquette, C.H., Mbano, I., McAdams, A.M., Metzger, R.J., Nabhan, A.N., Nyquist, S.K., Penland, L., Poirion, O.B., Poli, S., Qi, C.C., Queen, R., Reichart, D., Rosas, I., Schupp, J., Sinha, R., Sit, R.V., Slowikowski, K., Slyper, M., Smith, N., Sountoulidis, A., Strunz, M., Sun, D., Talavera-López, C., Tan, P., Tantivit, J., Travaglini, K.J., Tucker, N.R., Vernon, K., Wadsworth, M.H., Waldman, J., Wang, X., Yan, W., Zhao, W. and Ziegler, C.G.K.
bioRxiv
: 2020.04.19.049254.
21 April 2020
Increased and synchronous recruitment of release sites underlies hippocampal mossy fiber presynaptic potentiation.
Orlando, M., Dvorzhak, A., Bruentgens, F., Maglione, M., Rost, B.R., Sigrist, S.J., Breustedt, Jm and Schmitz, D.
bioRxiv
: 2020.08.21.260638.
21 August 2020
SIGLEC1 (CD169): a marker of active neuroinflammation in the brain but not in the blood of MS patients.
Ostendorf, L., Dittert, P., Biesen, R., Duchow, A., Stiglbauer, V., Ruprecht, K., Seelow, D., Niesner, R.A., Hauser, A.E., Paul, F. and Radbruch, H.
medRxiv
: 2020.12.18.20248500.
22 December 2020
A semi-automated intestinal organoid screening method demonstrates epigenetic control of epithelial maturation.
Ostrop, J., Zwiggelaar, R., Pedersen, M.T., Gerbe, F., Bösl, K., Lindholm, H.T., Díez-Sánchez, Al., Parmar, N., Radetzki, S., von Kries, J.P., Jay, P., Jensen, K.B., Arrowsmith, C. and Oudhoff, M.J.
bioRxiv
: 2020.07.23.217414.
24 July 2020
YAP and β-catenin co-operate to drive oncogenesis in basal breast cancer.
Quinn, H., Koren, E., Vogel, R., Popp, O., Mertins, P., Messerschmidt, C., Marangoni, E., Fuchs, Y. and Birchmeier, W.
bioRxiv
: 2020.06.05.115881.
6 June 2020
A CRISPR-Cas9-engineered mouse model for GPI anchor deficiency mirrors human phenotype and shows hippocampal synaptic dysfunctions.
Rodríguez de los Santos, M., Rivalan, M., David, F.S., Knaus, A., Stumpf, A., Velasquez, L.M., Voigt, A., Mattei, D., Long, M., Vogt, G., Wittler, L., Timmermann, B., Robinson, P.N., Horn, D., Mundlos, S., Kornak, U., Schmitz, D., Winter, Y. and Krawitz, P.M.
bioRxiv
: 2020.04.20.050591.
21 April 2020
Local microcircuitry of parasubiculum shows distinct and common features of excitatory and inhibitory connectivity.
Sammons, R.P., Tzilivaki, A. and Schmitz, D.
bioRxiv
: 2020.12.18.423400.
19 December 2020
Portability of scientific workflows in NGS data analysis: a case study.
Schiefer, C., Bux, M., Brandt, J., Messerschmidt, C., Reinert, K., Beule, D. and Leser, U.
arXiv
: 2006.03104.
4 June 2020
RBM20 phosphorylation on serine/arginine domain is crucial to regulate pre-mRNA splicing and protein shuttling in the heart.
Sun, M., Jin, Y., Zhu, C., Zhang, Y., Liss, M., Gotthardt, M., Ren, J., Ge, Y. and Guo, W.
bioRxiv
: 2020.09.15.297002.
15 September 2020
A census of cell types and paracrine interactions in colorectal cancer.
Uhlitz, F., Bischoff, P., Sieber, A., Obermayer, B., Blanc, E., Lüthen, M., Sawitzki, B., Kamphues, C., Beule, D., Sers, C., Horst, D., Blüthgen, N. and Morkel, M.
bioRxiv
: 2020.01.10.901579.
11 January 2020
Single-cell analysis of the 3D topologies of genomic loci using genome architecture mapping.
Welch, L.R., Baugher, C., Zhang, Y., Davis, T., Marzluff, W.F., Welch, J.D. and Pombo, A.
bioRxiv
: 2020.02.10.941047.
13 February 2020
IFT88 transports Gucy2d, a guanylyl cyclase, to maintain sensory cilia function in Drosophila.
Werner, S., Zitouni, S., Okenve-Ramos, P., Mendonça, S., Sporbert, A., Spalthoff, C., Göpfert, M.C., Jana, S.C. and Bettencourt-Dias, M.
bioRxiv
: 2020.12.15.417840.
15 December 2020
Rub1/NEDD8, a ubiquitin-like modifier, is also a ubiquitin modifier.
Zerath Gurevich, S., Sinha, A., Longworth, J., Singh, R.K., Lemma, B.E., Thakur, A., Popp, O., Kornitzer, D., Reis, N., Scheffner, M., Dittmar, G., Pick, E., Fushman, D. and Glickman, M.H.
bioRxiv
: 2020.06.18.159145.
19 June 2020
Serotonin suppresses slow oscillations by activating somatostatin interneurons via the 5-HT(2A) receptor.
de Filippo, R., Rost, B., Stumpf, A., Cooper, C., Tukker, J.J., Harms, C., Beed, P. and Schmitz, D.
bioRxiv
: 2020.05.26.113373.
26 May 2020
This list was generated on Sun Dec 22 06:21:20 2024 UTC.