Items where Year is 2020

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Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis.
Abrahamyan, S., Eberspächer, B., Hoshi, M.M., Aly, L., Luessi, F., Groppa, S., Klotz, L., Meuth, S.G., Schroeder, C., Grüter, T., Tackenberg, B., Paul, F., Then-Bergh, F., Kümpfel, T., Weber, F., Stangel, M., Bayas, A., Wildemann, B., Heesen, C., Zettl, U., Warnke, C., Antony, G., Hessler, N., Wiendl, H., Bittner, S., Hemmer, B., Gold, R., Salmen, A. and Ruprecht, K.
Journal of Neurology Neurosurgery and Psychiatry 91 (7): 681-686. July 2020

SUMOylation of enzymes and ion channels in sensory neurons protects against metabolic dysfunction, neuropathy, and sensory loss in diabetes.
Agarwal, N., Taberner, F.J., Rangel Rojas, D., Moroni, M., Omberbasic, D., Njoo, C., Andrieux, A., Gupta, P., Bali, K.K., Herpel, E., Faghihi, F., Fleming, T., Dejean, A., Lechner, S.G., Nawroth, P.P., Lewin, G.R. and Kuner, R.
Neuron 107 (6): 1141-1159. 23 September 2020

Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica.
Agasing, A.M., Wu, Q., Khatri, B., Borisow, N., Ruprecht, K., Brandt, A.U., Gawde, S., Kumar, G., Quinn, J.L., Ko, R.M., Mao-Draayer, Y., Lessard, C.J., Paul, F. and Axtell, R.C.
Nature Communications 11 (1): 2856. 5 June 2020

Consumption of fish and long-chain n-3 polyunsaturated fatty acids is associated with reduced risk of colorectal cancer in a large European cohort.
Aglago, E.K., Huybrechts, I., Murphy, N., Casagrande, C., Nicolas, G., Pischon, T., Fedirko, V., Severi, G., Boutron-Ruault, M.C., Fournier, A., Katzke, V., Kühn, T., Olsen, A., Tjønneland, A., Dahm, C.C., Overvad, K., Lasheras, C., Agudo, A., Sánchez, M.J., Amiano, P., Huerta, J.M., Ardanaz, E., Perez-Cornago, A., Trichopoulou, A., Karakatsani, A., Martimianaki, G., Palli, D., Pala, V., Tumino, R., Naccarati, A., Panico, S., Bueno-de-Mesquita, B., May, A., Derksen, J.W.G., Hellstrand, S., Ohlsson, B., Wennberg, M., Van Guelpen, B., Skeie, G., Brustad, M., Weiderpass, E., Cross, A.J., Ward, H., Riboli, E., Norat, T., Chajes, V. and Gunter, M.J.
Clinical Gastroenterology and Hepatology 18 (3): 654-666. March 2020

Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML).
Agrawal, M., Schwarz, P., Giaimo, B.D., Bedzhov, I., Corbacioglu, A., Weber, D., Gaidzik, V.I., Jahn, N., Rücker, F.G., Schroeder, T., Kindler, T., Wattad, M., Götze, K., Lübbert, M., Salwender, H., Ringhoffer, M., Lange, E., Koller, E., Thol, F., Heuser, M., Ganser, A., Bullinger, L., Paschka, P., Döhner, H., Geiger, H., Borggrefe, T., Döhner, K. and Oswald, F.
Leukemia 34 (2): 630-634. February 2020

CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development.
Aherrahrou, R., Kulle, A.E., Alenina, N., Werner, R., Vens-Cappell, S., Bader, M., Schunkert, H., Erdmann, J. and Aherrahrou, Z.
Scientific Reports 10 (1): 8792. 29 May 2020

Erforschung von Erkrankungen in der NAKO Gesundheitsstudie: die wichtigsten gesundheitlichen Endpunkte und ihre Erfassung [The investigation of health outcomes in the German National Cohort: the most relevant endpoints and their assessment].
Ahrens, W., Greiser, K.H., Linseisen, J., Pischon, T. and Pigeot, I.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (4): 376-384. April 2020

Das Fundament ist gelegt - für verbesserte Vorbeugung und Früherkennung der großen Volkskrankheiten [The foundation has been laid - for improved prevention and early detection of major common diseases].
Ahrens, W., Pigeot, I. and Pischon, T.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (4): 373-375. April 2020

Was macht krank, was hält uns gesund? [What makes us sick, what keeps us healthy?].
Ahrens, W., Pigeot, I. and Pischon, T.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (3): 251-253. March 2020

Computational genomics with R.
Akalin, A.
Chapman and Hall/CRC Computational Biology Series . CRC Press LLC, Milton. ISBN 9781498781855 2020

Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model.
Akpa, C.A., Kleo, K., Oker, E., Tomaszewski, N., Messerschmidt, C., López, C., Wagener, R., Oehl-Huber, K., Dettmer, K., Schoeler, A., Lenze, D., Oefner, P.J., Beule, D., Siebert, R., Capper, D., Dimitrova, L. and Hummel, M.
BMC Cancer 20 (1): 427. 14 May 2020

Single-cell and spatial transcriptomics approaches of the bone marrow microenvironment.
Al-Sabah, J., Baccin, C. and Haas, S.
Current Opinion in Oncology 32 (2): 146-153. 1 March 2020

Fingolimod after a first unilateral episode of acute optic neuritis (MOVING) - preliminary results from a randomized, rater-blind, active-controlled, phase 2 trial.
Albert, C., Mikolajczak, J., Liekfeld, A., Piper, S.K., Scheel, M., Zimmermann, H.G., Nowak, C., Dörr, J., Bellmann-Strobl, J., Chien, C., Brandt, A.U., Paul, F. and Hoffmann, O.
BMC Neurology 20 (1): 75. 3 March 2020

Pursuing experimental reproducibility: an efficient protocol for the preparation of cerebrospinal fluid samples for NMR-based metabolomics and analysis of sample degradation.
Albrecht, B., Voronina, E., Schipke, C., Peters, O., Parr, M.K., Díaz-Hernández, M.D. and Schlörer, N.E.
Metabolites 10 (6): 251. 16 June 2020

Tumor-derived extracellular vesicles impair CD171-specific CD4(+) CAR T cell efficacy.
Ali, S., Toews, K., Schwiebert, S., Klaus, A., Winkler, A., Grunewald, L., Oevermann, L., Deubzer, H.E., Tüns, A., Jensen, M.C., Henssen, A.G., Eggert, A., Schulte, J.H., Schwich, E., Rebmann, V., Schramm, A. and Künkele, A.
Frontiers in Immunology 11 : 531. 31 March 2020

Determinants of SARS-CoV-2 receptor gene expression in upper and lower airways.
Aliee, H., Massip, F., Qi, C., de Biase, M.S., van Nijnatten, J.L., Kersten, E.T.G., Kermani, N.Z., Khuder, B., Vonk, J.M., Vermeulen, R.C.H., Neighbors, M., Tew, G.W., Grimbaldeston, M., Ten Hacken, N.H.T., Hu, S., Guo, Y., Zhang, X., Sun, K., Hiemstra, P.S., Ponder, B.A., Makela, M.J., Malmstrom, K., Rintoul, R.C., Reyfman, P.A., Theis, F.J., Brandsma, C.A., Adcock, I., Timens, W., Xu, C.J., van den Berge, M., Schwarz, R.F., Koppelman, G.H., Nawijn, M.C. and Faiz, A.
medRxiv : 2020.08.31.20169946. 2 September 2020

Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats.
Alonso, L., Peeva, P., Ramos-Prats, A., Alenina, N., Winter, Y. and Rivalan, M.
Behavioural Brain Research 377 : 112188. 13 January 2020

DNA sonication inverse PCR for genome scale analysis of uncharacterized flanking sequences.
Alquezar‐Planas, D.E., Löber, U., Cui, P., Quedenau, C., Chen, W. and Greenwood, A.D.
Methods in Ecology and Evolution 22 September 2020

Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses.
Alsaleh, G., Panse, I., Swadling, L., Zhang, H., Richter, F.C., Meyer, A., Lord, J., Barnes, E., Klenerman, P., Green, C. and Simon, A.K.
eLife 9 : e57950. 15 December 2020

A palladium-catalyzed domino reaction to access 3-amino-2H-indazoles from hydrazines and 2-halobenzonitriles.
Alsalim, R., Lindemann, P., López-Alberca, M.P., Miksche, S., Czechtizky, W., Halland, N. and Nazaré, M.
Organic Letters 22 (18): 7393-7396. 18 September 2020

Novel basic science insights to improve the management of heart failure: review of the working group on cellular and molecular biology of the heart of the italian society of cardiology.
Ameri, P., Schiattarella, G.G., Crotti, L., Torchio, M., Bertero, E., Rodolico, D., Forte, M., Di Mauro, V., Paolillo, R., Chimenti, C., Torella, D., Catalucci, D., Sciarretta, S., Basso, C., Indolfi, C. and Perrino, C.
International Journal of Molecular Sciences 21 (4): 1192. 11 February 2020

Order and disorder: abnormal 3D chromatin organization in human disease.
Anania, C. and Lupianez, D.G.
Briefings in Functional Genomics 19 (2): 128-138. March 2020

RNA sequencing of human peripheral blood cells indicates upregulation of immune-related genes in Huntington's disease.
Andrade-Navarro, M.A., Mühlenberg, K., Spruth, E.J., Mah, N., González-López, A., Andreani, T., Russ, J., Huska, M.R., Muro, E.M., Fontaine, J.F., Amstislavskiy, V., Soldatov, A., Nietfeld, W., Wanker, E.E. and Priller, J.
Frontiers in Neurology 11 : 573560. 27 November 2020

Spatial heterogeneity in molecular brightness.
Annibale, P. and Lohse, M.J.
Nature Methods 17 (3): 273-275. March 2020

Imaging of clinically unrecognized myocardial fibrosis in patients with suspected coronary artery disease.
Antiochos, P., Ge, Y., Steel, K., Bingham, S., Abdullah, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
Journal of the American College of Cardiology 76 (8): 945-957. 25 August 2020

Evaluation of stress cardiac magnetic resonance imaging in risk reclassification of patients with suspected coronary artery disease.
Antiochos, P., Ge, Y., Steel, K., Chen, Y.Y., Bingham, S., Abdullah, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P., Murthy, V.L. and Kwong, R.Y.
JAMA Cardiology 5 (12): 1401-1409. December 2020

Early life stress regulates cardiac development through an IL4-glucocorticoid signaling balance.
Apaydin, D.C., Jaramillo, P.A.M., Corradi, L., Cosco, F., Rathjen, F.G., Kammertoens, T., Filosa, A. and Sawamiphak, S.
Cell Reports 33 (7): 108404. 17 November 2020

Gadobutrol-enhanced cardiac magnetic resonance imaging for detection of coronary artery disease.
Arai, A.E., Schulz-Menger, J., Berman, D., Mahrholdt, H., Han, Y., Bandettini, W.P., Gutberlet, M., Abraham, A., Woodard, P.K., Selvanayagam, J.B., McCann, G.P., Hamilton-Craig, C., Schoepf, U.J., Tan, R.S., Kramer, C.M., Friedrich, M.G., Haverstock, D., Liu, Z., Brueggenwerth, G., Bacher-Stier, C., Santiuste, M. and Pennell, D.J.
Journal of the American College of Cardiology 76 (13): 1536-1547. 29 September 2020

Clonal hematopoiesis in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis.
Arends, C.M., Weiss, M., Christen, F., Eulenberg-Gustavus, C., Rousselle, A., Kettritz, R., Eckardt, K.U., Chan, W., Hoyer, K., Frick, M., Bullinger, L., Bieringer, M., Schreiber, A. and Damm, F.
Haematologica 105 (6): e264-e267. June 2020

DeepWAS: multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.
Arloth, J., Eraslan, G., Andlauer, T.F.M., Martins, J., Iurato, S., Kühnel, B., Waldenberger, M., Frank, J., Gold, R., Hemmer, B., Luessi, F., Nischwitz, S., Paul, F., Wiendl, H., Gieger, C., Heilmann-Heimbach, S., Kacprowski, T., Laudes, M., Meitinger, T., Peters, A., Rawal, R., Strauch, K., Lucae, S., Müller-Myhsok, B., Rietschel, M., Theis, F.J., Binder, E.B. and Mueller, N.S.
PLoS Computational Biology 16 (2): e1007616. 3 February 2020

Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. and Treese, C.
Clinical and Translational Oncology 22 (12): 2357-2363. December 2020

Phenotype consensus is required to enable large-scale genetic consortium studies of food allergy.
Asai, Y., Martino, D., Eiwegger, T., Nadeau, K., Koppelman, G.H., Clarke, A.E., Lee, Y.A., Chan, E.S., Simons, E., Laprise, C., Mazer, B., Marenholz, I., Royce, D., Elliott, S.J., Hampson, C., Gerdts, J., Eslami, A., Soller, L., Hui, J., Azad, M., Sandford, A. and Daley, D.
Allergy 75 (9): 2383-2387. 23 April 2020

Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling.
Asaro, A., Carlo-Spiewok, A.S., Malik, A.R., Rothe, M., Schipke, C.G., Peters, O., Heeren, J. and Willnow, T.E.
Alzheimer's & Dementia 16 (9): 1248-1258. September 2020

Pain in NMOSD and MOGAD: a systematic literature review of pathophysiology, symptoms, and current treatment strategies.
Asseyer, S., Cooper, G. and Paul, F.
Frontiers in Neurology 11 : 778. 21 August 2020

Prodromal headache in MOG-antibody positive optic neuritis.
Asseyer, S., Hamblin, J., Messina, S., Mariano, R., Siebert, N., Everett, R., Küker, W., Bellmann-Strobl, J., Ruprecht, K., Jarius, S., Leite, M.I., Brandt, A., Paul, F. and Palace, J.
Multiple Sclerosis and Related Disorders 40 : 101965. May 2020

Ventral posterior nucleus volume is associated with neuropathic pain intensity in neuromyelitis optica spectrum disorders.
Asseyer, S., Kuchling, J., Gaetano, L., Komnenić, D., Siebert, N., Chien, C., Scheel, M., Oertel, F.C., Ruprecht, K., Bellmann-Strobl, J., Finke, C., Chakravarty, M.M., Magon, S., Wuerfel, J., Paul, F., Papadopoulou, A. and Brandt, A.U.
Multiple Sclerosis and Related Disorders 46 : 102579. November 2020

Wisdom of the expert crowd prediction of response for 3 neurology randomized trials.
Atanasov, P., Diamantaras, A., MacPherson, A., Vinarov, E., Benjamin, D.M., Shrier, I., Paul, F., Dirnagl, U. and Kimmelman, J.
Neurology 95 (5): e488-e498. 4 August 2020

Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and tetralogy of fallot and its functional evaluation in the Drosophila heart.
Auxerre-Plantié, E., Nielsen, T., Grunert, M., Olejniczak, O., Perrot, A., Özcelik, C., Harries, D., Matinmehr, F., Dos Remedios, C., Mühlfeld, C., Kraft, T., Bodmer, R., Vogler, G. and Sperling, S.R.
Disease Models & Mechanisms 13 (12): dmm045377. 18 December 2020

B

Loss of m(1)acp(3)Ψ ribosomal RNA modification is a major feature of cancer.
Babaian, A., Rothe, K., Girodat, D., Minia, I., Djondovic, S., Milek, M., Spencer Miko, S.E., Wieden, H.J., Landthaler, M., Morin, G.B. and Mager, D.L.
Cell Reports 31 (5): 107611. 5 May 2020

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.
Baccin, C., Al-Sabah, J., Velten, L., Helbling, P.M., Grünschläger, F., Hernández-Malmierca, P., Nombela-Arrieta, C., Steinmetz, L.M., Trumpp, A. and Haas, S.
Nature Cell Biology 22 (1): 38-48. January 2020

Cortical topological network changes following optic neuritis.
Backner, Y., Ben-Shalom, I., Kuchling, J., Siebert, N., Scheel, M., Ruprecht, K., Brandt, A., Paul, F. and Levin, N.
Neurology Neuroimmunology & Neuroinflammation 7 (3): e687. May 2020

Suppression of β1-adrenoceptor autoantibodies is involved in the antiarrhythmic effects of omega-3 fatty acids in male and female hypertensive rats.
Bacova, B.S., Radosinska, J., Wallukat, G., Barancik, M., Wallukat, A., Knezl, V., Sykora, M., Paulis, L. and Tribulova, N.
International Journal of Molecular Sciences 21 (2): 526. 14 January 2020

Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease.
Bader, J.M., Geyer, P.E., Müller, J.B., Strauss, M.T., Koch, M., Leypoldt, F., Koertvelyessy, P., Bittner, D., Schipke, C.G., Incesoy, E.I., Peters, O., Deigendesch, N., Simons, M., Jensen, M.K., Zetterberg, H. and Mann, M.
Molecular Systems Biology 16 (6): e9356. 1 June 2020

ACE2 - das missbrauchte Multitalent [ACE2 - the hijacked all-rounder].
Bader, M.
Nephrologe 15 (6): 375-380. November 2020

Inhibition of serotonin synthesis: a novel therapeutic paradigm.
Bader, M.
Pharmacology & Therapeutics 205 : 107423. January 2020

ACE2, a multifunctional protein - from cardiovascular regulation to COVID-19.
Bader, M., Turner, A.J. and Alenina, N.
Clinical Science 134 (23): 3229-3232. 11 December 2020

Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study.
Bahr, L.S., Bock, M., Liebscher, D., Bellmann-Strobl, J., Franz, L., Prüß, A., Schumann, D., Piper, S.K., Kessler, C.S., Steckhan, N., Michalsen, A., Paul, F. and Mähler, A.
Trials 21 (1): 3. 2 January 2020

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey, M.H., Meyerson, W.U., Dursi, L.J., Wang, L.B., Dong, G., Liang, W.W., Weerasinghe, A., Li, S., Li, Y., Kelso, S., Saksena, G., Ellrott, K., Wendl, M.C., Wheeler, D.A., Getz, G., Simpson, J.T., Gerstein, M.B. and Ding, Li
Nature Communications 11 (1): 4748. 21 September 2020

The positional logic of sensory-motor reflex circuit assembly.
Balaskas, N., Ng, D. and Zampieri, N.
Neuroscience 450 : 142-150. 1 December 2020

Consensus-based technical recommendations for clinical translation of renal BOLD MRI.
Bane, O., Mendichovszky, I.A., Milani, B., Dekkers, I.A., Deux, J.F., Eckerbom, P., Grenier, N., Hall, M., Inoue, T., Laustsen, C., Lerman, L., Liu, C., Morrell, G., Pedersen, M., Pruijm, M., Sadowski, E., Seeliger, E., Sharma, K., Thoeny, H., Vermathen, P., Wang, Z., Serafin, Z., Zhang, J., Francis, S., Sourbron, S., Pohlmann, A., Fain, S. and Prasad, P.
Magnetic Resonance Materials in Physics Biology and Medicine 33 : 199-215. February 2020

SuperCYPsPred - a web server for the prediction of cytochrome activity.
Banerjee, P., Dunkel, M., Kemmler, E. and Preissner, R.
Nucleic Acids Research 48 (W1): W580-W585. July 2020

Co-activation of NF-κB and MYC renders cancer cells addicted to IL6 for survival and phenotypic stability.
Barbosa, R.R., Xu, A.Q., D'Andrea, D., Copley, F., Patel, H., Chakravarty, P., Clear, A., Calaminici, M., Janz, M., Zhang, B., Schmidt-Supprian, M., Wang, J., Gribben, J.G., Tooze, R., Fitzgibbon, J., Franzoso, G., Rajewsky, K. and Calado, D.P.
bioRxiv : 2020.04.12.038414. 13 April 2020

Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Barone, M., Müller, M., Chiha, S., Ren, J., Albat, D., Soicke, A., Dohmen, S., Klein, M., Bruns, J., van Dinther, M., Opitz, R., Lindemann, P., Beerbaum, M., Motzny, K., Roske, Y., Schmieder, P., Volkmer, R., Nazaré, M., Heinemann, U., Oschkinat, H., Ten Dijke, P., Schmalz, H.G. and Kühne, R.
Proceedings of the National Academy of Sciences of the United States of America 117 (47): 29684-29690. 24 November 2020

Blood pressure changes correlate with short-chain fatty acid production potential shifts under a synbiotic intervention.
Bartolomaeus, H., Avery, E.G., Bartolomaeus, T.U.P., Kozhakhmetov, S., Zhumadilov, Z., Müller, D.N., Wilck, N., Kushugulova, A. and Forslund, S.K.
Cardiovascular Research 116 (7): 1252-1253. June 2020

Darm-Herz-Achse: Wie Darmbakterien kardiovaskuläre Erkrankungen beeinflussen [Gut-heart axis: how gut bacteria influence cardiovascular diseases].
Bartolomaeus, H., McParland, V. and Wilck, N.
Herz 45 (2): 134-141. April 2020

Hitchhiker's guide to microbiome studies.
Bartolomaeus, T.U.P. and Forslund, S.K.
Cardiovascular Research 116 (3): e44-e47. 1 March 2020

Induction and analysis of oxidative stress in Sleeping Beauty transposon-transfected human retinal pigment epithelial cells.
Bascuas, T., Kropp, M., Harmening, N., Asrih, M., Izsvák, Z. and Thumann, G.
Journal of Visualized Experiments 2020 (166): e61957. 11 December 2020

Enhancement of CRISPR-Cas9 induced precise gene editing by targeting Histone H2A-K15 ubiquitination.
Bashir, S., Dang, T., Rossius, J., Wolf, J. and Kuehn, R.
BMC Biotechnology 20 (1): 57. 23 October 2020

CD40 provides immune privilege to the bone marrow hematopoietic niche.
Bassani, B., Gulino, A., Portararo, P., Botti, L., Cappetti, B., Chiodoni, C., Bolli, N., Ciciarello, M., Joehrens, K., Anagnostopoulos, I., Na, I.K., Curti, A., Tripodo, C., Colombo, M.P. and Sangaletti, S.
bioRxiv : 2020.08.10.243691. 10 August 2020

Unblending of transcriptional condensates in human repeat expansion disease.
Basu, S., Mackowiak, S.D., Niskanen, H., Knezevic, D., Asimi, V., Grosswendt, S., Geertsema, H., Ali, S., Jerković, I., Ewers, H., Mundlos, S., Meissner, A., Ibrahim, D.M. and Hnisz, D.
Cell 181 (5): 1062-1079. 28 May 2020

Linescan microscopy data to extract diffusion coefficient of a fluorescent species using a commercial confocal microscope.
Bathe-Peters, M., Gmach, P., Annibale, P. and Lohse, M.J.
Data in Brief 29 : 105063. April 2020

Paternal exercise protects against liver steatosis in the male offspring of mice submitted to high fat diet.
Batista, R.O., Budu, A., Alves-Silva, T., Arakaki, A.M., Gregnani, M.F.S., Rodrigues Húngaro, T.G., Burgos-Silva, M., Wasinski, F., Lanzoni, V.P., Camara, N.O.S., Oyama, L.M., Bader, M. and Araújo, R.C.
Life Sciences 263 : 118583. 15 December 2020

Establishment of kidney cancer organoid cultures.
Bauer, D., Birchmeier, W. and Fendler, A.
Research Square : rs.3.pex-911. 12 May 2020

LoopDetect: comprehensive feedback loop detection in ordinary differential equation models.
Baum, K. and Wolf, J.
bioRxiv : 2020.11.15.383703. 17 November 2020

Analysing central metabolism in ultra-high resolution: at the crossroads of carbon and nitrogen.
Bayram, S., Fürst, S., Forbes, M. and Kempa, S.
Molecular Metabolism 33 : 38-47. 19 March 2020

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia.
Becker, H., Pfeifer, D., Ihorst, G., Pantic, M., Wehrle, J., Rüter, B.H., Bullinger, L., Hackanson, B., Germing, U., Kuendgen, A., Platzbecker, U., Döhner, K., Ganser, A., Hagemeijer, A., Wijermans, P.W., Döhner, H., Duyster, J. and Lübbert, M.
Annals of Hematology 99 (7): 1551-1560. July 2020

Fast myocardial T(1) mapping using cardiac motion correction.
Becker, K.M., Blaszczyk, E., Funk, S., Nuesslein, A., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Magnetic Resonance in Medicine 83 (2): 438-451. February 2020

Genetic information from discordant sibling pairs points to ESRP2 as a candidate trans-acting regulator of the CF modifier gene SCNN1B.
Becker, T., Pich, A., Tamm, S., Hedtfeld, S., Ibrahim, M., Altmüller, J., Dalibor, N., Toliat, M.R., Janciauskiene, S., Tümmler, B. and Stanke, F.
Scientific Reports 10 (1): 22447. 31 December 2020

Species-specific differences in synaptic transmission and plasticity.
Beed, P., Ray, S., Velasquez, L.M., Stumpf, A., Parthier, D., Swaminathan, A., Nitzan, N., Breustedt, J., Las, L., Brecht, M. and Schmitz, D.
Scientific Reports 10 (1): 16557. 6 October 2020

Layer 3 pyramidal cells in the medial entorhinal cortex orchestrate up-down states and entrain the deep layers differentially.
Beed, P., de Filippo, R., Holman, C., Johenning, F.W., Leibold, C., Caputi, A., Monyer, H. and Schmitz, D.
Cell Reports 33 (10): 108470. 8 December 2020

Disentangling pro-mitotic signaling during cell cycle progression using time-resolved single-cell imaging.
Benary, M., Bohn, S., Lüthen, M., Nolis, I.K., Blüthgen, N. and Loewer, A.
Cell Reports 31 (2): 107514. 14 April 2020

Assessment of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids, in patients with persistent atrial fibrillation: rationale and design of the PROMISE-AF phase II study.
Berlin, S., Goette, A., Summo, L., Lossie, J., Gebauer, A., Al-Saady, N., Calo, L., Naccarelli, G., Schunck, W.H., Fischer, R., Camm, A.J. and Dobrev, D.
International Journal of Cardiology (IJC) Heart & Vasculature 29 : 100573. August 2020

Conduction delays in the visual pathways of progressive multiple sclerosis patients covary with brain structure.
Berman, S., Backner, Y., Krupnik, R., Paul, F., Petrou, P., Karussis, D., Levin, N. and Mezer, A.A.
NeuroImage 221 : 117204. 1 November 2020

Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19.
Bernardes, J.P., Mishra, N., Tran, F., Bahmer, T., Best, L., Blase, J.I., Bordoni, D., Franzenburg, J., Geisen, U., Josephs-Spaulding, J., Köhler, P., Künstner, A., Rosati, E., Aschenbrenner, A.C., Bacher, P., Baran, N., Boysen, T., Brandt, B., Bruse, N., Dörr, J., Dräger, A., Elke, G., Ellinghaus, D., Fischer, J., Forster, M., Franke, A., Franzenburg, S., Frey, N., Friedrichs, A., Fuß, J., Glück, A., Hamm, J., Hinrichsen, F., Hoeppner, M.P., Imm, S., Junker, R., Kaiser, S., Kan, Y.H., Knoll, R., Lange, C., Laue, G., Lier, C., Lindner, M., Marinos, G., Markewitz, R., Nattermann, J., Noth, R., Pickkers, P., Rabe, K.F., Renz, A., Röcken, C., Rupp, J., Schaffarzyk, A., Scheffold, A., Schulte-Schrepping, J., Schunk, D., Skowasch, D., Ulas, T., Wandinger, K.P., Wittig, M., Zimmermann, J., Busch, H., Hoyer, B.F., Kaleta, C., Heyckendorf, J., Kox, M., Rybniker, J., Schreiber, S., Schultze, J.L. and Rosenstiel, P.
Immunity 53 (6): 1296-1314. 15 December 2020

Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer.
Berndt, N., Egners, A., Mastrobuoni, G., Vvedenskaya, O., Fragoulis, A., Dugourd, A., Bulik, S., Pietzke, M., Bielow, C., van Gassel, R., Olde Damink, S.W., Erdem, M., Saez-Rodriguez, J., Holzhütter, H.G., Kempa, S. and Cramer, T.
British Journal of Cancer 122 (2): 233-244. 21 January 2020

Computational approaches from polymer physics to investigate chromatin folding.
Bianco, S., Chiariello, A.M., Conte, M., Esposito, A., Fiorillo, L., Musella, F. and Nicodemi, M.
Current Opinion in Cell Biology 64 : 10-17. June 2020

SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
Biederstädt, A., Hassan, Z., Schneeweis, C., Schick, M., Schneider, L., Muckenhuber, A., Hong, Y., Siegers, G., Nilsson, L., Wirth, M., Dantes, Z., Steiger, K., Schunck, K., Langston, S., Lenhof, H.P., Coluccio, A., Orben, F., Slawska, J., Scherger, A., Saur, D., Müller, S., Rad, R., Weichert, W., Nilsson, J., Reichert, M., Schneider, G. and Keller, U.
Gut 69 (8): 1472-1482. August 2020

Untangling the conformational polymorphism of disordered proteins associated with neurodegeneration at the single-molecule level.
Birol, M. and Melo, A.M.
Frontiers in Molecular Neuroscience 12 : 309. 10 January 2020

Normal-range urinary albumin excretion associates with blood pressure and renal electrolyte handling in pregnancy.
Birukov, A., Andersen, M.S., Jørgensen, J.S., Kitlen, G., Rakova, N., Nielsen, J.H., Andersen, L.B., Dechend, R. and Jensen, B.L.
American Journal of Physiology Renal Physiology 319 (1): F1-F7. July 2020

Myocardial evaluation of post-preeclamptic women by CMR: is early risk stratification possible?
Birukov, A., Wiesemann, S., Golic, M., Balogh, A., Marko, L., Rakova, N., Wilck, N., Blaszczyk, E., Lim, C., Weiss, S., Kräker, K., Haase, N., Frolova, A., Jørgensen, J.S., Daub, S., Mueller, D.N., Herse, F., Schulz-Menger, J. and Dechend, R.
JACC: Cardiovascular Imaging 13 (5): 1291-1293. May 2020

Blood pressure and angiogenic markers in pregnancy: contributors to pregnancy-induced hypertension and offspring cardiovascular risk.
Birukov, A.., Herse, F., Nielsen, J.H., Kyhl, H.B., Golic, M., Kräker, K., Haase, N., Busjahn, A., Bruun, S., Jensen, B.L., Müller, D.N., Jensen, T.K., Christesen, H.T., Andersen, M.S., Jørgensen, J.S., Dechend, R. and Andersen, L.B.
Hypertension 76 (3): 901-909. September 2020

Clinical implications of serum neurofilament in newly diagnosed MS patients: a longitudinal multicentre cohort study.
Bittner, S., Steffen, F., Uphaus, T., Muthuraman, M., Fleischer, V., Salmen, A., Luessi, F., Berthele, A., Klotz, L., Meuth, S.G., Bayas, A., Paul, F., Hartung, H.P., Linker, R., Heesen, C., Stangel, M., Wildemann, B., Then Bergh, F., Tackenberg, B., Kuempfel, T., Weber, F., Zettl, U.K., Ziemann, U., Tumani, H., Groppa, S., Mühlau, M., Lukas, C., Hemmer, B., Wiendl, H., Gold, R. and Zipp, F.
EBioMedicine 56 : 102807. June 2020

Evaluation of the 'ring sign' and the 'core sign' as a magnetic resonance imaging marker of disease activity and progression in clinically isolated syndrome and early multiple sclerosis.
Blindenbacher, N., Brunner, E., Asseyer, S., Scheel, M., Siebert, N., Rasche, L., Bellmann-Strobl, J., Brandt, A., Ruprecht, K., Meier, D., Wuerfel, J., Paul, F. and Sinnecker, T.
Multiple Sclerosis Journal Experimental Translational and Clinical 6 (1): 2055217320915480. 30 March 2020

Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB).
Blois, S.M., Verlohren, S., Wu, G., Clark, G., Dell, A., Haslam, S.M. and Barrientos, G.
Seminars in Immunopathology 42 (4): 469-486. August 2020

Investigating APOE, APP-Aβ metabolism genes and Alzheimer's disease GWAS hits in brain small vessel ischemic disease.
Blumenau, S., Foddis, M., Müller, S., Holtgrewe, M., Bentele, K., Berchtold, D., Beule, D., Dirnagl, U. and Sassi, C.
Scientific Reports 10 (1): 7103. 28 April 2020

Optical mapping of cAMP signaling at the nanometer scale.
Bock, A., Annibale, P., Konrad, C., Hannawacker, A., Anton, S.E., Maiellaro, I., Zabel, U., Sivaramakrishnan, S., Falcke, M. and Lohse, M.J.
Cell 182 (6): 1519-1530. 17 September 2020

Heart-specific immune responses in an animal model of autoimmune-related myocarditis mitigated by an immunoproteasome inhibitor and genetic ablation.
Bockstahler, M., Fischer, A., Goetzke, C.C., Neumaier, H.L., Sauter, M., Kespohl, M., Müller, A.M., Meckes, C., Salbach, C., Schenk, M., Heuser, A., Landmesser, U., Weiner, J., Meder, B., Lehmann, L., Kratzer, A., Klingel, K., Katus, H.A., Kaya, Z. and Beling, A.
Circulation 141 (23): 1885-1902. 9 June 2020

Cardiorenal sodium MRI in small rodents using a quadrature birdcage volume resonator at 9.4 T.
Boehmert, L., Waiczies, H., Kuehne, A., Oezerdem, C., Waiczies, S., Starke, L., Ku, M.C., Pohlmann, A., Seeliger, E. and Niendorf, T.
Magnetic Resonance Materials in Physics Biology and Medicine 33 (1): 121-130. February 2020

Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis.
Bogdanow, B., Schmidt, M., Weisbach, H., Gruska, I., Vetter, B., Imami, K., Ostermann, E., Brune, W., Selbach, M., Hagemeier, C. and Wiebusch, L.
Nature Communications 11 (1): 4845. 24 September 2020

Functional roles of Grainyhead-like transcription factors in renal development and disease.
Boivin, F.J. and Schmidt-Ott, K.M.
Pediatric Nephrology 35 (2): 181-190. February 2020

VISOR: a versatile haplotype-aware structural variant simulator for short- and long-read sequencing.
Bolognini, D., Sanders, A., Korbel, J.O., Magi, A., Benes, V. and Rausch, T.
Bioinformatics 36 (4): 1267-1269. 15 February 2020

Oxidative metabolism drives immortalization of neural stem cells during tumorigenesis.
Bonnay, F., Veloso, A., Steinmann, V., Köcher, T., Abdusselamoglu, M.D., Bajaj, S., Rivelles, E., Landskron, L., Esterbauer, H., Zinzen, R.P. and Knoblich, J.A.
Cell 182 (6): 1490-1507. 17 September 2020

Altered glycosylation contributes to placental dysfunction upon early disruption of the NK cell-DC dynamics.
Borowski, S., Tirado-Gonzalez, I., Freitag, N., Garcia, M.G., Barrientos, G. and Blois, S.M.
Frontiers in Immunology 11 : 1316. 14 July 2020

Fine-tuning stemness.
Borsa, M. and Simon, A.K.
Science 369 (6502): 373-374. 24 July 2020

Effects of dietary protein-load and alkaline supplementation on acid-base balance and glucose metabolism in healthy elderly.
Boschmann, M., Kaiser, N., Klasen, A., Klug, L., Mähler, A., Michalsen, A., Vormann, J., Werner, T. and Stange, R.
European Journal of Clinical Nutrition 74 : 48-56. August 2020

An activatable lanthanide luminescent probe for time-gated detection of nitroreductase in live bacteria.
Brennecke, B., Wang, Q., Zhang, Q., Hu, H.Y. and Nazaré, M.
Angewandte Chemie International Edition 59 (22): 8512-8516. 25 May 2020

iPSC modeling of RBM20-deficient DCM identifies upregulation of RBM20 as a therapeutic strategy.
Briganti, F., Sun, H., Wei, W., Wu, J., Zhu, C., Liss, M., Karakikes, I., Rego, S., Cipriano, A., Snyder, M., Meder, B., Xu, Z., Millat, G., Gotthardt, M., Mercola, M. and Steinmetz, L.M.
Cell Reports 32 (10): 108117. 8 September 2020

Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial.
Bröckelmann, P.J., Goergen, H., Keller, U., Meissner, J., Ordemann, R., Halbsguth, T.V., Sasse, S., Sökler, M., Kerkhoff, A., Mathas, S., Hüttmann, A., Bormann, M., Zimmermann, A., Mettler, J., Fuchs, M., von Tresckow, B., Baues, C., Rosenwald, A., Klapper, W., Kobe, C., Borchmann, P. and Engert, A.
JAMA Oncology 6 (6): 872-880. June 2020

Cardiovascular disease in women: insights from magnetic resonance imaging.
Bucciarelli-Ducci, C., Ostenfeld, E., Baldassarre, L.A., Ferreira, V.M., Frank, L., Kallianos, K., Raman, S.V., Srichai, M.B., McAlindon, E., Mavrogeni, S., Ntusi, N.A.B., Schulz-Menger, J., Valente, A.M. and Ordovas, K.G.
Journal of Cardiovascular Magnetic Resonance 22 (1): 71. 28 September 2020

mRNAs, proteins and the emerging principles of gene expression control.
Buccitelli, C. and Selbach, M.
Nature Reviews Genetics 21 (10): 630-644. October 2020

Decoding and targeting the molecular basis of MACC1-driven metastatic spread: lessons from big data mining and clinical-experimental approaches.
Budczies, J., Kluck, K., Walther, W. and Stein, U.
Seminars in Cancer Biology 60 : 365-379. February 2020

Comprehensive molecular analysis of 61 Egyptian families with hereditary nonsyndromic hearing loss.
Budde, B.S., Aly, M.A., Mohamed, M.R., Breß, A., Altmüller, J., Motameny, S., Kawalia, A., Thiele, H., Konrad, K., Becker, C., Toliat, M.R., Nürnberg, G., Sayed, E.A.F., Mohamed, E.S., Pfister, M. and Nürnberg, P.
Clinical Genetics 98 (1): 32-42. July 2020

Genomic rewiring of SOX2 chromatin interaction network during differentiation of ESCs to postmitotic neurons.
Bunina, D., Abazova, N., Diaz, N., Noh, K.M., Krijgsveld, J. and Zaugg, J.B.
Cell Systems 10 (6): 480-494. 24 June 2020

Vitamin D and disease severity in multiple sclerosis-baseline data from the randomized controlled trial (EVIDIMS).
Bäcker-Koduah, P., Bellmann-Strobl, J., Scheel, M., Wuerfel, J., Wernecke, K.D., Dörr, J., Brandt, A.U. and Paul, F.
Frontiers in Neurology 11 : 129. 25 February 2020

Effect of vitamin D supplementation on N-glycan branching and cellular immunophenotypes in MS.
Bäcker-Koduah, P., Infante-Duarte, C., Ivaldi, F., Uccelli, A., Bellmann-Strobl, J., Wernecke, K.D., Sy, M., Demetriou, M., Dörr, J., Paul, F. and Brandt, A.U.
Annals of Clinical and Translational Neurology 7 (9): 1628-1641. September 2020

Prediction of birth weight small for gestational age with and without preeclampsia by angiogenic markers: an Odense Child Cohort Study.
Bækgaard Thorsen, L.H., Bjørkholt Andersen, L., Birukov, A., Lykkedegn, S., Dechend, R., Stener Jørgensen, J. and Thybo Christesen, H.
Journal of Maternal-Fetal & Neonatal Medicine 33 (8): 1377-1384. April 2020

NF-κB signaling in tanycytes mediates inflammation-induced anorexia.
Böttcher, M., Müller-Fielitz, H., Sundaram, S.M., Gallet, S., Neve, V., Shionoya, K., Zager, A., Quan, N., Liu, X., Schmidt-Ullrich, R., Haenold, R., Wenzel, J., Blomqvist, A., Engblom, D., Prevot, V. and Schwaninger, M.
Molecular Metabolism 39 : 101022. September 2020

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Human and mouse essentiality screens as a resource for disease gene discovery.
Cacheiro, P., Muñoz-Fuentes, V., Murray, S.A., Dickinson, M.E., Bucan, M., Nutter, L.M.J., Peterson, K.A., Haselimashhadi, H., Flenniken, A.M., Morgan, H., Westerberg, H., Konopka, T., Hsu, C.W., Christiansen, A., Lanza, D.G., Beaudet, A.L., Heaney, J.D., Fuchs, H., Gailus-Durner, V., Sorg, T., Prochazka, J., Novosadova, V., Lelliott, C.J., Wardle-Jones, H., Wells, S., Teboul, L., Cater, H., Stewart, M., Hough, T., Wurst, W., Sedlacek, R., Adams, D.J., Seavitt, J.R., Tocchini-Valentini, G., Mammano, F., Braun, R.E., McKerlie, C., Herault, Y., de Angelis, M.H., Mallon, A.M., Lloyd, K.C.K., Brown, S.D.M., Parkinson, H., Meehan, T.F. and Smedley, D.
Nature Communications 11 (1): 655. 31 January 2020

Real-time visualization of titin dynamics reveals extensive reversible photobleaching in human induced pluripotent stem cell-derived cardiomyocytes.
Cadar, A.G., Feaster, T.K., Bersell, K.R., Wang, L., Hong, T.T., Balsamo, J.A., Zhang, Z., Chun, Y.W., Nam, Y.J., Gotthardt, M., Knollmann, B.C., Roden, D.M., Lim, C.C. and Hong, C.C.
American Journal of Physiology Cell Physiology 318 (1): C163-C173. January 2020

Genomic basis for RNA alterations in cancer.
Calabrese, C., Davidson, N.R., Demircioğlu, D., Fonseca, N.A., He, Y., Kahles, A., Lehmann, K.V., Liu, F., Shiraishi, Y., Soulette, C.M., Urban, L., Greger, L., Li, S., Liu, D., Perry, M.D., Xiang, Q., Zhang, F., Zhang, J., Bailey, P., Erkek, S., Hoadley, K.A., Hou, Y., Huska, M.R., Kilpinen, H., Korbel, J.O., Marin, M.G., Markowski, J., Nandi, T., Pan-Hammarström, Q., Pedamallu, C.S., Siebert, R., Stark, S.G., Su, H., Tan, P., Waszak, S.M., Yung, C., Zhu, S., Awadalla, P., Creighton, C.J., Meyerson, M., Ouellette, B.F.F., Wu, K., Yang, H., Brazma, A., Brooks, A.N., Göke, J., Rätsch, G., Schwarz, R.F., Stegle, O. and Zhang, Z.
Nature 578 (7793): 129-136. 6 February 2020

Quantification of translation uncovers the functions of the alternative transcriptome.
Calviello, L., Hirsekorn, A. and Ohler, U.
Nature Structural & Molecular Biology 27 (8): 717-725. August 2020

Imagine physiology without imaging.
Cantow, K., Hummel, L., Flemming, B., Waiczies, S., Niendorf, T. and Seeliger, E.
Acta Physiologica 230 (3): e13549. November 2020

Single-cell lineage tracing approaches in hematology research: technical considerations.
Carrelha, J., Lin, D.S., Rodriguez-Fraticelli, A.E., Luis, T.C., Wilkinson, A.C., Cabezas-Wallscheid, N., Tremblay, C.S. and Haas, S.
Experimental Hematology 89 : 26-36. September 2020

Endothelial cells don't waste: endothelial-derived lactate boosts muscle regeneration.
Castro, M., Andrade, J. and Potente, M.
Developmental Cell 54 (2): 137-139. 20 July 2020

Control of neutrophil influx during peritonitis by transcriptional cross-regulation of chemokine CXCL1 by IL-17 and IFN-γ.
Catar, R.A., Chen, L., Cuff, S.M., Kift-Morgan, A., Eberl, M., Kettritz, R., Kamhieh-Milz, J., Moll, G., Li, Q., Zhao, H., Kawka, E., Zickler, D., Parekh, G., Davis, P., Fraser, D.J., Dragun, D., Eckardt, K.U., Jörres, A. and Witowski, J.
Journal of Pathology 251 (2): 175-186. June 2020

Impact of treatment on cellular immunophenotype in MS: a cross-sectional study.
Cellerino, M., Ivaldi, F., Pardini, M., Rotta, G., Vila, G., Bäcker-Koduah, P., Berge, T., Laroni, A., Lapucci, C., Novi, G., Boffa, G., Sbragia, E., Palmeri, S., Asseyer, S., Høgestøl, E., Campi, C., Piana, M., Inglese, M., Paul, F., Harbo, H.F., Villoslada, P., Kerlero de Rosbo, N. and Uccelli, A.
Neurology Neuroimmunology & Neuroinflammation 7 (3): e693. May 2020

Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils.
Cerofolini, L., Ravera, E., Bologna, S., Wiglenda, T., Böddrich, A., Purfürst, B., Benilova, I., Korsak, M., Gallo, G., Rizzo, D., Gonnelli, L., Fragai, M., De Strooper, B., Wanker, E.E. and Luchinat, C.
Chemical Communications 56 (62): 8830-8833. 11 August 2020

Peripheral mechanisms of arthritic pain: a proposal to leverage large animals for in vitro studies.
Chakrabarti, S., Ai, M., Henson, F.M.D. and Smith, E.S.J.
Neurobiology of Pain 8 : 100051. 28 August 2020

Visual system damage and network maladaptation are associated with cognitive performance in neuromyelitis optica spectrum disorders.
Chavarro, V.S., Bellmann-Strobl, J., Zimmermann, H.G., Scheel, M., Chien, C., Oertel, F.C., Weygandt, M., Ruprecht, K., Paul, F., Finke, C. and Brandt, A.U.
Multiple Sclerosis and Related Disorders 45 : 102406. October 2020

Longitudinal ultra-high field MRI of brain lesions in neuromyelitis optica spectrum disorders.
Chawla, S., Ge, Y., Wuerfel, J., Asadollahi, S., Mohan, S., Paul, F., Sinnecker, T. and Kister, I.
Multiple Sclerosis and Related Disorders 42 : 102066. July 2020

Structure of RyR1 in native membranes.
Chen, W. and Kudryashev, M.
EMBO Reports 21 (5): e49891. 6 May 2020

A dynamic folded hairpin conformation is associated with α-globin activation in erythroid cells.
Chiariello, A.M., Bianco, S., Oudelaar, A M., Esposito, A., Annunziatella, C., Fiorillo, L., Conte, M., Corrado, A., Prisco, A., Larke, M.S.C., Telenius, J.M., Sciarretta, R., Musella, F., Buckle, V.J., Higgs, D.R., Hughes, J.R. and Nicodemi, M.
Cell Reports 30 (7): 2125-2135. 18 February 2020

Considerations for mean upper cervical cord area implementation in a longitudinal MRI setting: methods, interrater reliability, and MRI quality control.
Chien, C., Juenger, V., Scheel, M., Brandt, A.U. and Paul, F.
American Journal of Neuroradiology 41 (2): 343-350. 1 February 2020

What is extrachromosomal circular DNA and what does it do?
Chiu, R.W.K., Dutta, A., Henssen, A.G., Lo, Y.M.D., Mischel, P. and Regenberg, B.
Clinical Chemistry 66 (6): 754-759. June 2020

Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chong, C., Müller, M., Pak, H.S., Harnett, D., Huber, F., Grun, D., Leleu, M., Auger, A., Arnaud, M., Stevenson, B.J., Michaux, J., Bilic, I., Hirsekorn, A., Calviello, L., Simó-Riudalbas, L., Planet, E., Lubiński, J., Bryśkiewicz, M., Wiznerowicz, M., Xenarios, I., Zhang, L., Trono, D., Harari, A., Ohler, U., Coukos, G. and Bassani-Sternberg, M.
Nature Communications 11 (1): 1293. 10 March 2020

Structure of the active GGEEF domain of a diguanylate cyclase from Vibrio cholerae.
Chouhan, O.P., Roske, Y., Heinemann, U. and Biswas, S.
Biochemical and Biophysical Research Communications 523 (2): 287-292. 5 March 2020

LRP2 controls sonic hedgehog-dependent differentiation of cardiac progenitor cells during outflow tract formation.
Christ, A., Marczenke, M. and Willnow, T.E.
Human Molecular Genetics 29 (19): 3183-3196. 1 October 2020

A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort.
Christakoudi, S., Tsilidis, K.K., Muller, D.C., Freisling, H., Weiderpass, E., Overvad, K., Söderberg, S., Häggström, C., Pischon, T., Dahm, C.C., Zhang, J., Tjønneland, A., Halkjær, J., MacDonald, C., Boutron-Ruault, M.C., Mancini, F.R., Kühn, T., Kaaks, R., Schulze, M.B., Trichopoulou, A., Karakatsani, A., Peppa, E., Masala, G., Pala, V., Panico, S., Tumino, R., Sacerdote, C., Quirós, J.R., Agudo, A., Sánchez, M.J., Cirera, L., Barricarte-Gurrea, A., Amiano, P., Memarian, E., Sonestedt, E., Bueno-de-Mesquita, B., May, A.M., Khaw, K.T., Wareham, N.J., Tong, T.Y.N., Huybrechts, I., Noh, H., Aglago, E.K., Ellingjord-Dale, M., Ward, H.A., Aune, D. and Riboli, E.
Scientific Reports 10 (1): 14541. 3 September 2020

Intron with transgenic marker (InTraM) facilitates high-throughput screening of endogenous gene reporter lines.
Collins, R.T., Coxam, B., Fechner, I., Unterweger, I., Szymborska, A., Meier, K. and Gerhardt, H.
Genesis 58 (10-11): e23391. November 2020

Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing.
Conrad, T., Ntini, E., Lang, B., Cozzuto, L., Andersen, J.B., Marquardt, J.U., Ponomarenko, J., Tartaglia, G.G. and Vang Orom, U.A.
RNA 26 (11): 1726-1730. November 2020

Maximizing transcription of nucleic acids with efficient T7 promoters.
Conrad, T., Plumbom, I., Alcobendas, M., Vidal, R. and Sauer, S.
Communications Biology 3 (1): 439. 14 August 2020

Polymer physics indicates chromatin folding variability across single-cells results from state degeneracy in phase separation.
Conte, M., Fiorillo, L., Bianco, S., Chiariello, A.M., Esposito, A. and Nicodemi, M.
Nature Communications 11 (1): 3289. 3 July 2020

Quantitative multi-parameter mapping optimized for the clinical routine.
Cooper, G., Hirsch, S., Scheel, M., Brandt, A.U., Paul, F., Finke, C., Boehm-Sturm, P. and Hetzer, S.
Frontiers in Neuroscience 14 : 611194. 7 December 2020

Endothelial damage and dysfunction in acute graft-versus-host disease.
Cordes, S., Mokhtari, Z., Bartosova, M., Mertlitz, S., Riesner, K., Shi, Y., Mengwasser, J., Kalupa, M., McGeary, A., Schleifenbaum, J., Schrezenmeier, J., Bullinger, L., Diaz-Ricart, M., Palomo, M., Carrreras, E., Beutel, G., Schmitt, C.P., Beilhack, A. and Penack, O.
Haematologica 106 (8): 2147-2160. 1 August 2020

A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis.
Coscia, F., Doll, S., Bech, J.M., Schweizer, L., Mund, A., Lengyel, E., Lindebjerg, J., Madsen, G.I., Moreira, J.M. and Mann, M.
Journal of Pathology 251 (1): 100-112. May 2020

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription.
Cossa, G., Roeschert, I., Prinz, F., Baluapuri, A., Silveira Vidal, R., Schülein-Völk, C., Chang, Y.C., Ade, C.P., Mastrobuoni, G., Girard, C., Kumar, A., Wortmann, L., Walz, S., Lührmann, R., Kempa, S., Kuster, B., Wolf, E., Mumberg, D. and Eilers, M.
Molecular Cell 77 (6): 1322-1339. 19 March 2020

A specialized niche in the pancreatic microenvironment promotes endocrine differentiation.
Cozzitorto, C., Mueller, L., Ruzittu, S., Mah, N., Willnow, D., Darrigrand, J.F., Wilson, H., Khosravinia, D., Mahmoud, A.A., Risolino, M., Selleri, L. and Spagnoli, F.M.
Developmental Cell 55 (2): 150-162. 26 October 2020

Short-term western diet aggravates non-alcoholic fatty liver disease (NAFLD) with portal hypertension in TGR(mREN2)27 rats.
Cremonese, C., Schierwagen, R., Uschner, F.E., Torres, S., Tyc, O., Ortiz, C., Schulz, M., Queck, A., Kristiansen, G., Bader, M., Sauerbruch, T., Weiskirchen, R., Walther, T., Trebicka, J. and Klein, S.
International Journal of Molecular Sciences 21 (9): 3308. 1 May 2020

Myogenic vasoconstriction requires canonical Gq/11 signaling of the angiotensin II type 1a receptor in the murine vasculature.
Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y.M., Schleifenbaum, J., Bader, M., Welsh, D.G., Huang, Y. and Gollasch, M.
bioRxiv : 2020.09.09.289280. 11 September 2020

Revalorization of bioactive compounds from tropical fruit by-products and industrial applications by means of sustainable approaches.
Cádiz-Gurrea, M.L., Villegas-Aguilar, M.C., Leyva-Jiménez, F.J., Pimentel-Moral, S., Fernández-Ochoa, Á., Alañón, M.E. and Segura-Carretero, A.
Food Research International 138 (Part B): 109786. December 2020

D

Diagnostic procedures in suspected attacks in patients with neuromyelitis optica spectrum disorders: results of an international survey.
D'Souza, M., Papadopoulou, A., Levy, M., Jacob, A., Yeaman, M.R., Kümpfel, T., Marignier, R., Paul, F. and Brandt, A.U.
Multiple Sclerosis and Related Disorders 41 : 102027. June 2020

Restoring treatment response in colorectal cancer cells by targeting MACC1-dependent ABCB1 expression in combination therapy.
Dahlmann, M., Werner, R., Kortüm, B., Kobelt, D., Walther, W. and Stein, U.
Frontiers in Oncology 10 : 599. 23 April 2020

Novel targets of protoporphyrin-IX determined by gene expression analysis.
Dai, Y. and Kemmner, W.
International Journal of Clinical Oncology and Cancer Research 5 (3): 56-64. September 2020

N2 year in review.
Dalmau, J., Dalakas, M.C., Kolson, D.L., Paul, F. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 7 (1): e644. January 2020

The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel, B., Czimmerer, Z., Halasz, L., Boto, P., Kolostyak, Z., Poliska, S., Berger, W.K., Tzerpos, P., Nagy, G., Horvath, A., Hajas, G., Cseh, T., Nagy, A., Sauer, S., Francois-Deleuze, J., Szatmari, I., Bacsi, A. and Nagy, L.
Genes & Development 34 (21-22): 1474-1492. 1 November 2020

The pierced lasso topology leptin has a bolt on dynamic domain composed by the disordered loops I and III.
Danielsson, J., Noel, J.K., Simien, J.M., Duggan, B.M., Oliveberg, M., Onuchic, J.N., Jennings, P.A. and Haglund, E.
Journal of Molecular Biology 432 (9): 3050-3063. 17 April 2020

TIM-3 and CEACAM1 do not interact in cis and in trans.
De Sousa Linhares, A., Kellner, F., Jutz, S., Zlabinger, G.J., Gabius, H.J., Huppa, J.B., Leitner, J. and Steinberger, P.
European Journal of Immunology 50 (8): 1126-1141. August 2020

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Delgado-Benito, V., Berruezo-Llacuna, M., Altwasser, R., Winkler, W., Sundaravinayagam, D., Balasubramanian, S., Caganova, M., Graf, R., Rahjouei, A., Henke, M.T., Driesner, M., Keller, L., Prigione, A., Janz, M., Akalin, A. and Di Virgilio, M.
Journal of Experimental Medicine 217 (10): e20200137. 5 October 2020

Cyclin-dependent kinase 18 controls trafficking of aquaporin-2 and its abundance through ubiquitin ligase STUB1, which functions as an AKAP.
Dema, A., Faust, D., Lazarow, K., Wippich, M., Neuenschwander, M., Zühlke, K., Geelhaar, A., Pallien, T., Hallscheidt, E., Eichhorst, J., Wiesner, B., Cernecká, H., Popp, O., Mertins, P., Dittmar, G., von Kries, J.P. and Klussmann, E.
Cells 9 (3): 673. 10 March 2020

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P., Newman, A.G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., Kleinau, G., Derkow, K., Richard, B.C., Schipke, C., Scheidereit, C., Stachelscheid, H., Golenbock, D., Peters, O., Coleman, M., Heppner, F.L., Scheerer, P., Tarabykin, V., Ruprecht, K., Izsvák, Z., Mayer, J. and Lehnardt, S.
JCI Insight 5 (7): e131093. 9 April 2020

Reproducibility of heart rate variability revealed by repeated measurements during and after hemodialysis.
Deussing, K., Wendt, R., Burger, R., Gollasch, M. and Beige, J.
Blood Purification 49 (3): 356-363. May 2020

HMGXB4 targets Sleeping Beauty transposition to vertebrate germinal stem sells.
Devaraj, A., Singh, M., Narayanavari, S., Yong, G., Wang, J., Wang, J., Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z., Grzela, D., Raskó, T., Selbach, M., Ivics, Z. and Izsvák, Z.
bioRxiv : 2020.06.15.145656. 15 June 2020

RNA-sequencing and somatic mutation status of adrenocortical tumors: novel pathogenetic insights.
Di Dalmazi, G., Altieri, B., Scholz, C., Sbiera, S., Luconi, M., Waldman, J., Kastelan, D., Ceccato, F., Chiodini, I., Arnaldi, G., Riester, A., Osswald, A., Beuschlein, F., Sauer, S., Fassnacht, M., Appenzeller, S. and Ronchi, C.L.
Journal of Clinical Endocrinology & Metabolism 105 (12): dgaa616. December 2020

Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.
Dias D'Andréa, E., Roske, Y., de Oliveira, G.A.P., Cremer, N., Diehl, A., Schmieder, P., Heinemann, U., Oschkinat, H. and Ricardo Pires, J.
Journal of Structural Biology 211 (2): 107536. 1 August 2020

Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.
Dietrich, M., Koska, V., Hecker, C., Göttle, P., Hilla, A.M., Heskamp, A., Lepka, K., Issberner, A., Hallenberger, A., Baksmeier, C., Steckel, J., Balk, L., Knier, B., Korn, T., Havla, J., Martínez-Lapiscina, E.H., Solà-Valls, N., Manogaran, P., Olbert, E.D., Schippling, S., Cruz-Herranz, A., Yiu, H., Button, J., Caldito, N.G., von Gall, C., Mausberg, A.K., Stettner, M., Zimmermann, H.G., Paul, F., Brandt, A.U., Küry, P., Goebels, N., Aktas, O., Berndt, C., Saidha, S., Green, A.J., Calabresi, P.A., Fischer, D., Hartung, H.P. and Albrecht, P.
Brain 143 (4): 1127-1142. April 2020

Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation.
Dimchev, G., Amiri, B., Humphries, A.C., Schaks, M., Dimchev, V., Stradal, T.E.B., Faix, J., Krause, M., Way, M., Falcke, M. and Rottner, K.
Journal of Cell Science 133 (7): jcs239020. 9 April 2020

Novel loss-of-function variants in CDC14A are associated with recessive sensorineural hearing loss in Iranian and Pakistani patients.
Doll, J., Kolb, S., Schnapp, L., Rad, A., Rüschendorf, F., Khan, I., Adli, A., Hasanzadeh, A., Liedtke, D., Knaup, S., Hofrichter, M.A., Müller, T., Dittrich, M., Kong, I.K., Kim, H.G., Haaf, T. and Vona, B.
International Journal of Molecular Sciences 21 (1): 311. 2 January 2020

Genetic spectrum of syndromic and non-syndromic hearing loss in Pakistani families.
Doll, J., Vona, B., Schnapp, L., Rüschendorf, F., Khan, I., Khan, S., Muhammad, N., Alam Khan, S., Nawaz, H., Khan, A., Ahmad, N., Kolb, S.M., Kühlewein, L., Labonne, J.D.J., Layman, L.C., Hofrichter, M.A.H., Röder, T., Dittrich, M., Müller, T., Graves, T.D., Kong, I.K., Nanda, I., Kim, H.G. and Haaf, T.
Genes 11 (11): 1329. 11 November 2020

Polypeptide-corticosteroid conjugates as a topical treatment approach to psoriasis.
Dolz-Pérez, I., Sallam, M.A., Masiá, E., Morelló-Bolumar, D., Pérez Del Caz, M.D., Graff, P., Abdelmonsif, D., Hedtrich, S., Nebot, V.J. and Vicent, M.J.
Journal of Controlled Release 318 : 210-222. February 2020

Soziodemografische und erwerbsbezogene Merkmale in der NAKO Gesundheitsstudie [Socio-demographic and employment-related factors in the German National Cohort (GNC; NAKO Gesundheitsstudie)].
Dragano, N., Reuter, M., Greiser, K.H., Becher, H., Zeeb, H., Mikolajczyk, R., Kluttig, A., Leitzmann, M., Fischer, B., Jöckel, K.H., Emmel, C., Krause, G., Castell, S., Damms-Machado, A., Obi, N., Schikowski, T., Kuss, O., Hoffmann, W., Schipf, S., Pischon, T., Jaeschke, L., Krist, L., Keil, T., Lieb, W., Holleczek, B., Brenner, H., Wirkner, K., Loeffler, M., Michels, K.B., Franzke, C.W., Peters, A., Linseisen, J., Berger, K., Legath, N., Ahrens, W., Lampert, T. and Schmidt, B.
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 63 (3): 267-278. March 2020

Association between fatigue and motor exertion in patients with multiple sclerosis - a prospective study.
Drebinger, D., Rasche, L., Kroneberg, D., Althoff, P., Bellmann-Strobl, J., Weygandt, M., Paul, F., Brandt, A.U. and Schmitz-Hübsch, T.
Frontiers in Neurology 11 : 208. 15 April 2020

A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome.
Drivas, T.G., Li, D., Nair, D., Alaimo, J.T., Alders, M., Altmüller, J., Barakat, T.S., Bebin, E.M., Bertsch, N.L., Blackburn, P.R., Blesson, A., Bouman, A.M., Brockmann, K., Brunelle, P., Burmeister, M., Cooper, G.M., Denecke, J., Dieux-Coëslier, A., Dubbs, H., Ferrer, A., Gal, D., Bartik, L.E., Gunderson, L.B., Hasadsri, L., Jain, M., Karimov, C., Keena, B., Klee, E.W., Kloth, K., Lace, B., Macchiaiolo, M., Marcadier, J.L., Milunsky, J.M., Napier, M.P., Ortiz-Gonzalez, X.R., Pichurin, P.N., Pinner, J., Powis, Z., Prasad, C., Radio, F.C., Rasmussen, K.J., Renaud, D.L., Rush, E.T., Saunders, C., Selcen, D., Seman, A.R., Shinde, D.N., Smith, E.D., Smol, T., Snijders Blok, L., Stoler, J.M., Tang, S., Tartaglia, M., Thompson, M.L., van de Kamp, J.M., Wang, J., Weise, D., Weiss, K., Woitschach, R., Wollnik, B., Yan, H., Zackai, E.H., Zampino, G., Campeau, P. and Bhoj, E.
European Journal of Human Genetics 28 (10): 1422-1431. October 2020

Emerging drugs for the treatment of neuromyelitis optica.
Duchow, A., Chien, C., Paul, F. and Bellmann-Strobl, J.
Expert Opinion on Emerging Drugs 25 (3): 285-297. September 2020

Current and emerging biologics for the treatment of neuromyelitis optica spectrum disorders.
Duchow, A., Paul, F. and Bellmann-Strobl, J.
Expert Opinion on Biological Therapy 20 (9): 1061-1072. September 2020

Initiating a new national epilepsy surgery program: experiences gathered in Georgia.
Dugladze, T., Bäuerle, P., Kasradze, S., Lomidze, G., Gzirishvili, N., Tsikarishvili, Vl., Khurtsidze, G., Vida, I., Schmitz, D., Schneider, U.C., Holtkamp, M. and Gloveli, T.
Epilepsy & Behavior 111 : 107259. October 2020

Macrophage Cell-Cell Interactions Promoting HIV-1 Infection.
Dupont, M. and Sattentau, Q.J.
Viruses 12 (5): 492. 28 April 2020

Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism.
Duscha, A., Gisevius, B., Hirschberg, S., Yissachar, N., Stangl, G.I., Eilers, E., Bader, V., Haase, S., Kaisler, J., David, C., Schneider, R., Troisi, R., Zent, D., Hegelmaier, T., Dokalis, N., Gerstein, S., Del Mare-Roumani, S., Amidror, S., Staszewski, O., Poschmann, G., Stühler, K., Hirche, F., Balogh, A., Kempa, S., Träger, P., Zaiss, M.M., Holm, J.B., Massa, M.G., Nielsen, H.B., Faissner, A., Lukas, C., Gatermann, S.G., Scholz, M., Przuntek, H., Prinz, M., Forslund, S.K., Winklhofer, K.F., Müller, D.N., Linker, R.A., Gold, R. and Haghikia, A.
Cell 180 (6): 1067-1080. 19 March 2020

Brain iron and metabolic abnormalities in C19orf12 mutation carriers: a 7.0 tesla MRI study in mitochondrial membrane protein-associated neurodegeneration.
Dusek, P., Mekle, R., Skowronska, M., Acosta-Cabronero, J., Huelnhagen, T., Robinson, S.D., Schubert, F., Deschauer, M., Els, A., Ittermann, B., Schottmann, G., Madai, V.I., Paul, F., Klopstock, T., Kmiec, T., Niendorf, T., Wuerfel, J. and Schneider, S.A.
Movement Disorders 35 (1): 142-150. January 2020

Functional classification of TP53 mutations in acute myeloid leukemia.
Dutta, S., Pregartner, G., Rücker, F.G., Heitzer, E., Zebisch, A., Bullinger, L., Berghold, A., Döhner, K. and Sill, H.
Cancers 12 (3): 637. 10 March 2020

Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin.
Dyring-Andersen, B., Løvendorf, M.B., Coscia, F., Santos, A., Møller, L.B.P., Colaço, A.R., Niu, L., Bzorek, M., Doll, S., Andersen, J.L., Clark, R.A., Skov, L., Teunissen, M.B.M. and Mann, M.
Nature Communications 11 (1): 5587. 5 November 2020

Longtime outcome after intraosseous application of autologous mesenchymal stromal cells in pediatric patients and young adults with avascular necrosis after steroid or chemotherapy.
Döring, M., Kluba, T., Cabanillas Stanchi, K.M., Kahle, P., Lenglinger, K., Tsiflikas, I., Treuner, C., Vaegler, M., Mezger, M., Erbacher, A., Schumm, M., Lang, P., Handgretinger, R. and Müller, I.
Stem Cells and Development 29 (13): 811-822. July 2020

High-dose vitamin D supplementation in multiple sclerosis - results from the randomized EVIDIMS (efficacy of vitamin D supplementation in multiple sclerosis) trial.
Dörr, J., Koduah, P., Wernecke, K.D., Becker, E., Hoffmann, F., Faiss, J., Brockmeier, B., Hoffmann, O., Anvari, K., Wuerfel, J., Piper, S.K., Bellmann-Strobl, J., Brandt, A.U. and Paul, F.
Multiple Sclerosis Journal Experimental Translational and Clinical 6 (1): 2055217320903474. 24 January 2020

B(1) and B(2) kinin receptor blockade improves psoriasis-like disease.
da Silva Soley, B., Silva, L.M., Mendes, D.A.G.B., Báfica, A., Pesquero, J.B., Bader, M., Witherden, D.A., Havran, W.L., Calixto, J.B., Otuki, M.F. and Cabrini, D.A.
British Journal of Pharmacology 177 (15): 3535-3551. August 2020

Serotonin suppresses slow oscillations by activating somatostatin interneurons via the 5-HT(2A) receptor.
de Filippo, R., Rost, B., Stumpf, A., Cooper, C., Tukker, J.J., Harms, C., Beed, P. and Schmitz, D.
bioRxiv : 2020.05.26.113373. 26 May 2020

C/EBPβ-dependent epigenetic memory induces trained immunity in hematopoietic stem cells.
de Laval, B., Maurizio, J., Kandalla, P.K., Brisou, G., Simonnet, L., Huber, C., Gimenez, G., Matcovitch-Natan, O., Reinhardt, S., David, E., Mildner, A., Leutz, A., Nadel, B., Bordi, C., Amit, I., Sarrazin, S. and Sieweke, M.H.
Cell Stem Cell 26 (5): 657-674. May 2020

E

Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Edelmann, J., Holzmann, K., Tausch, E., Saunderson, E.A., Jebaraj, B.M.C., Steinbrecher, D., Dolnik, A., Blätte, T.J., Landau, D.A., Saub, J., Estenfelder, S., Ibach, S., Cymbalista, F., Leblond, V., Delmer, A., Bahlo, J., Robrecht, S., Fischer, K., Goede, V., Bullinger, L., Wu, C.J., Mertens, D., Ficz, G., Gribben, J.G., Hallek, M., Döhner, H. and Stilgenbauer, S.
Haematologica 105 (5): 1379-1390. May 2020

Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.
Eede, P., Obst, J., Benke, E., Yvon-Durocher, G., Richard, B.C., Gimber, N., Schmoranzer, J., Böddrich, A., Wanker, E.E., Prokop, S. and Heppner, F.L.
EMBO Reports 21 (3): e48530. 4 March 2020

Wideband self-grounded bow-tie antenna for thermal MR.
Eigentler, T.W., Winter, L., Han, H., Oberacker, E., Kuehne, A., Waiczies, H., Schmitter, S., Boehmert, L., Prinz, C., Trefna, H.D. and Niendorf, T.
NMR in Biomedicine 33 (5): e4274. May 2020

Harnessing spatial homogeneity of neuroimaging data: patch individual filter layers for CNNs.
Eitel, F., Albrecht, J.P., Weygandt, M., Paul, F. and Ritter, K.
arXiv : 2007.11899. 23 July 2020

Aggressive multiple sclerosis - a matter of measurement and timing.
Ellenberger, D., Flachenecker, P., Fneish, F., Frahm, N., Hellwig, K., Paul, F., Stahmann, A., Warnke, C., Rommer, P.S. and Zettl, U.K.
Brain 143 (11): e97. November 2020

Is benign MS really benign? What a meaningful classification beyond the EDSS must take into consideration.
Ellenberger, D., Flachenecker, P., Haas, J., Hellwig, K., Paul, F., Stahmann, A., Warnke, C., Zettl, U.K. and Rommer, P.S.
Multiple Sclerosis and Related Disorders 46 : 102485. November 2020

Neurofibromatosis 1 - mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects.
Elmadany, N., Logiacco, F., Buonfiglioli, A., Haage, V., Wright-Jin, E.C., Schattenberg, A., Papawassiliou, R., Kettenmann, H., Semtner, M. and Gutmann, D.H.
Neurobiology of Disease 144 : 105030. October 2020

The VGF-derived peptide TLQP21 impairs purinergic control of chemotaxis and phagocytosis in mouse microglia.
Elmadany, N., de Almeida Sassi, F., Wendt, S., Logiacco, F., Visser, J., Haage, V., Perez Hernandez, D., Mertins, P., Hambardzumyan, D., Wolf, S., Kettenmann, H. and Semtner, M.
Journal of Neuroscience 40 (17): 3320-3331. 22 April 2020

Investigation of TEMPO partitioning in different skin models as measured by EPR spectroscopy - insight into the stratum corneum.
Elpelt, A., Ivanov, D., Nováčková, A., Kováčik, A., Sochorová, M., Saeidpour, S., Teutloff, C., Lohan, S.B., Lademann, J., Vávrová, K., Hedtrich, S. and Meinke, M.C.
Journal of Magnetic Resonance 310 : 106637. January 2020

Melanozytäre Naevi der Haut bei einem Neugeborenen [Dermal melanocytic nevi in a newborn].
Endres, S., Wilke, M., Höche, A., Gertz, A., Schubert, R., Deubzer, H., Eggert, A., Rossi, R. and Schlembach, D.
Gynäkologe 53 (8): 554-556. August 2020

Is APOE ε4 associated with cognitive performance in early MS?
Engel, S., Graetz, C., Salmen, A., Muthuraman, M., Toenges, G., Ambrosius, B., Bayas, A., Berthele, A., Heesen, C., Klotz, L., Kümpfel, T., Linker, R.A., Meuth, S.G., Paul, F., Stangel, M., Tackenberg, B., Then Bergh, F., Tumani, H., Weber, F., Wildemann, B., Zettl, U.K., Antony, G., Bittner, S., Groppa, S., Hemmer, B., Wiendl, H., Gold, R., Zipp, F., Lill, C.M. and Luessi, F.
Neurology Neuroimmunology & Neuroinflammation 7 (4): e728. July 2020

Phosphodiesterase 3A and arterial hypertension.
Ercu, M., Markó, L., Schächterle, C., Tsvetkov, D., Cui, Y., Maghsodi, S., Bartolomaeus, T.U.P., Maass, P.G., Zühlke, K., Gregersen, N., Hübner, N., Hodge, R., Mühl, A., Pohl, B., Molé-Illas, R., Geelhaar, A., Walter, S., Napieczynska, H., Schelenz, S., Taube, M., Heuser, A., Anistan, Y.M., Qadri, F., Todiras, M., Plehm, R., Popova, E., Langanki, R., Eichhorst, J., Lehmann, M., Wiesner, B., Russwurm, M., Forslund, S.K., Kamer, I., Müller, D.N., Gollasch, M., Aydin, A., Bähring, S., Bader, M., Luft, F.C. and Klussmann, E.
Circulation 142 (2): 133-149. 14 July 2020

cfNOMe - a single assay for comprehensive epigenetic analyses of cell-free DNA.
Erger, F., Nörling, D., Borchert, D., Leenen, E., Habbig, S., Wiesener, M.S., Bartram, M.P., Wenzel, A., Becker, C., Toliat, M.R., Nürnberg, P., Beck, B.B. and Altmüller, J.
Genome Medicine 12 (1): 54. 24 June 2020

A multi-vendor, multi-center study on reproducibility and comparability of fast strain-encoded cardiovascular magnetic resonance imaging.
Erley, J., Zieschang, V., Lapinskas, T., Demir, A., Wiesemann, S., Haass, M., Osman, N.F., Simonetti, O.P., Liu, Y., Patel, A.R., Mor-Avi, V., Unal, O., Johnson, K.M., Pieske, B., Hansmann, J., Schulz-Menger, J. and Kelle, S.
International Journal of Cardiovascular Imaging 36 (5): 899-911. May 2020

Feeding diastolic dysfunction: is it a bug?
Esposito, G. and Schiattarella, G.G.
Journal of Cardiac Failure 26 (8): 703-704. August 2020

Angiotensin-converting enzyme inhibitor protects against cisplatin nephrotoxicity by modulating kinin B1 receptor expression and aminopeptidase P activity in mice.
Estrela, G.R., Wasinski, F., Gregnani, M.F., Freitas-Lima, L.C., Arruda, A.C., Morais, R.L., Malheiros, D.M.A.C., Camara, N.O.S., Pesquero, J.B., Bader, M., Barros, C.C. and Araújo, R.C.
Frontiers in Molecular Biosciences 7 : 96. 20 May 2020

Generation of sharp wave-ripple events by disinhibition.
Evangelista, R., Cano, G., Cooper, C., Schmitz, D., Maier, N. and Kempter, R.
Journal of Neuroscience 40 (41): 7811-7836. 7 October 2020

Extracellular myocardial volume in patients with aortic stenosis.
Everett, R.J., Treibel, T.A., Fukui, M., Lee, H., Rigolli, M., Singh, A., Bijsterveld, P., Tastet, L., Musa, T.A., Dobson, L., Chin, C., Captur, G., Om, S.Y., Wiesemann, S., Ferreira, V.M., Piechnik, S.K., Schulz-Menger, J., Schelbert, E.B., Clavel, M.A., Newby, D.E., Myerson, S.G., Pibarot, P., Lee, S., Cavalcante, J.L., Lee, S.P., McCann, G.P., Greenwood, J.P., Moon, J.C. and Dweck, M.R.
Journal of the American College of Cardiology 75 (3): 304-316. 28 January 2020

F

Binding patterns and functional properties of human antibodies to AQP4 and MOG on murine optic nerve and retina.
Faissner, S., Graz, F., Reinehr, S., Petrikowski, L., Haupeltshofer, S., Ceylan, U., Stute, G., Winklmeier, S., Pache, F., Paul, F., Ruprecht, K., Meinl, E., Dick, H.B., Gold, R., Kleiter, I. and Joachim, S.C.
Journal of Neuroimmunology 342 : 577194. 15 May 2020

Loss of Piccolo function in rats induces cerebellar network dysfunction and Pontocerebellar Hypoplasia type 3-like phenotypes.
Falck, J., Bruns, C., Hoffmann-Conaway, S., Straub, I., Plautz, E.J., Orlando, M., Munawar, H., Rivalan, M., Winter, Y., Izsvák, Z., Schmitz, D., Hamra, F.K., Hallermann, S., Curtis Garner, C. and Ackermann, F.
Journal of Neuroscience 40 (14): 2943-2959. 1 April 2020

Age attenuates the T-type Ca(V) 3.2-RyR axis in vascular smooth muscle.
Fan, G., Kaßmann, M., Cui, Y., Matthaeus, C., Kunz, S., Zhong, C., Zhu, S., Xie, Yu, Tsvetkov, D., Daumke, O., Huang, Yu and Gollasch, M.
Aging Cell 19 (4): e13134. April 2020

Self-organizing 3D human trunk neuromuscular organoids.
Faustino Martins, J.M., Fischer, C., Urzi, A., Vidal, R., Kunz, S., Ruffault, P.L., Kabuss, L., Hube, I., Gazzerro, E., Birchmeier, C., Spuler, S., Sauer, S. and Gouti, M.
Cell Stem Cell 26 (2): 172-186. 6 February 2020

Stability of neuropsychological test performance in older adults serving as normative controls for a study on postoperative cognitive dysfunction.
Feinkohl, I., Borchers, F., Burkhardt, S., Krampe, H., Kraft, A., Speidel, S., Kant, I.M.J., van Montfort, S.J.T., Aarts, E., Kruppa, J., Slooter, A., Winterer, G., Pischon, T. and Spies, C.
BMC Research Notes 13 (1): 55. 4 February 2020

Plasma leptin, but not adiponectin, is associated with cognitive impairment in older adults.
Feinkohl, I., Janke, J., Slooter, A.J.C., Winterer, G., Spies, C. and Pischon, T.
Psychoneuroendocrinology 120 : 104783. October 2020

Plasma amyloid concentration in Alzheimer's disease: performance of a high-throughput amyloid assay in distinguishing Alzheimer's disease cases from controls.
Feinkohl, I., Schipke, C.G., Kruppa, J., Menne, F., Winterer, G., Pischon, T. and Peters, O.
Journal of Alzheimer's Disease 74 (4): 1285-1294. 21 April 2020

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients.
Fendler, A., Bauer, D., Busch, J., Jung, K., Wulf-Goldenberg, A., Kunz, S., Song, K., Myszczyszyn, A., Elezkurtaj, S., Erguen, B., Jung, S., Chen, W. and Birchmeier, W.
Nature Communications 11 (1): 929. 17 February 2020

Stimulation of mGluR1/5 improves defective internalization of AMPA receptors in NPC1 mutant mouse.
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Cerebral Cortex 30 (3): 1465-1480. March 2020

FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth.
Ferdous, A., Wang, Z.V., Luo, Y., Li, D.L., Luo, X., Schiattarella, G.G., Altamirano, F., May, H.I., Battiprolu, P.K., Nguyen, A., Rothermel, B.A., Lavandero, S., Gillette, T.G. and Hill, J.A.
Nature Communications 11 (1): 2551. 21 May 2020

Autocalibrated cardiac tissue phase mapping with multiband imaging and k-t acceleration.
Ferrazzi, G., Bassenge, J.P., Mayer, J., Ruh, A., Roujol, S., Ittermann, B., Schaeffter, T., Cordero-Grande, L. and Schmitter, S.
Magnetic Resonance in Medicine 84 (5): 2429-2441. November 2020

Age-of-onset information helps identify 76 genetic variants associated with allergic disease.
Ferreira, M.A.R., Vonk, J.M., Baurecht, H., Marenholz, I., Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, Vi., Lu, Y., Grosche, S., Rüschendorf, F., Granell, R., Brumpton, B.M., Fritsche, L.G., Bhatta, L., Gabrielsen, M.E., Nielsen, J.B., Zhou, W., Hveem, K., Langhammer, A., Holmen, O.L., Løset, M., Abecasis, G.R., Willer, C.J., Emami, N.C., Cavazos, T.B., Witte, J.S., Szwajda, A., Hinds, D.A., Hübner, N., Weidinger, S., Magnusson, P.K., Jorgenson, E., Karlsson, R., Paternoster, L., Boomsma, D.I., Almqvist, C., Lee, Y.A. and Koppelman, G.H.
PLoS Genetics 16 (6): e1008725. 30 June 2020

Identifying progression in multiple sclerosis: new perspectives.
Filippi, M., Preziosa, P., Langdon, D., Lassmann, H., Paul, F., Rovira, À., Schoonheim, M.M., Solari, A., Stankoff, B. and Rocca, M.A.
Annals of Neurology 88 (3): 438-452. September 2020

Inference of chromosome 3D structures from GAM data by a physics computational approach.
Fiorillo, L., Bianco, S., Chiariello, A.M., Barbieri, M., Esposito, A., Annunziatella, C., Conte, M., Corrado, A., Prisco, A., Pombo, A. and Nicodemi, M.
Methods 181-182 : 70-79. 1 October 2020

Anthropometrische Messungen in der NAKO Gesundheitsstudie - mehr als nur Größe und Gewicht [Anthropometric measures in the German National Cohort - more than weight and height].
Fischer, B., Sedlmeier, A.M., Hartwig, S., Schlett, C.L., Ahrens, W., Bamberg, F., Baurecht, H., Becher, H., Berger, K., Binder, H., Bohn, B., Carr, P.R., Castell, S., Franzke, C.W., Fricke, J., Gastell, S., Greiser, K.H., Günther, K., Jaeschke, L., Kaaks, R., Kemmling, Y., Krist, L., Kuß, O., Legath, N., Lieb, W., Linseisen, J., Löffler, M., Michels, K.B., Mikolajczyk, R., Niedermaier, T., Norman, K., Obi, N., Peters, A., Pischon, T., Schikowski, T., Schipf, S., Schmidt, B., Schulze, M.B., Stang, A., Stojicic, J., Tiller, D., Völzke, H., Waniek, S. and Leitzmann, M.F.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (3): 290-300. March 2020

Induced pluripotent stem cell-based disease modeling identifies ligand-induced decay of megalin as a cause of Donnai-Barrow syndrome.
Flemming, J., Marczenke, M., Rudolph, I.M., Nielsen, R., Storm, T., Ilsoe Christensen, E., Diecke, S., Emma, F. and Willnow, T.E.
Kidney International 98 (1): 159-167. July 2020

An exploratory investigation of brain collateral circulation plasticity after cerebral ischemia in two experimental C57BL/6 mouse models.
Foddis, M., Winek, K., Bentele, K., Mueller, S., Blumenau, S., Reichhart N, N., Crespo-Garcia, S., Harnett, D., Ivanov, A., Meisel, A., Joussen, A., Strauss, O., Beule, D., Dirnagl, U. and Sassi, C.
Journal of Cerebral Blood Flow and Metabolism 40 (2): 276-287. 1 February 2020

CD8-specific designed ankyrin repeat proteins improve selective gene delivery into human and primate T lymphocytes.
Frank, A.M., Weidner, T., Brynza, J., Uckert, W., Buchholz, C.J. and Hartmann, J.
Human Gene Therapy 31 (11-12): 679-691. June 2020

Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency.
Freitag, N., Tirado-Gonzalez, I., Barrientos, G., Powell, K.L., Boehm-Sturm, P., Koch, S.P., Hecher, K., Staff, A.C., Arck, P.C., Diemert, A. and Blois, S.M.
Cell Death & Disease 11 (7): 560. 23 July 2020

The Chimera-type galectin-3 is a positive modulator of trophoblast functions with dysregulated expression in gestational diabetes mellitus.
Freitag, N., Tirado-González, I., Barrientos, G., Cohen, M., Daher, S., Goldman-Wohl, D., Mincheva-Nilsson, L., John, C., Jeschke, U. and Blois, S.M.
American Journal of Reproductive Immunology 84 (6): e13311. December 2020

Dissecting HSV-1-induced host shut-off at RNA level.
Friedel, C.C., Whisnant, A.W., Djakovic, L., Rutkowski, A.J., Friedl, M.S., Kluge, M., Williamson, J.C., Sai, S., Oliveira Vidal, R., Sauer, S., Hennig, T., Prusty, B., Lehner, P.J., Matheson, N.J., Erhard, F. and Dölken, L.
bioRxiv : 2020.05.20.106039. 20 May 2020

Progression-dependent altered metabolism in osteosarcoma resulting in different nutrient source dependencies.
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Cancers 12 (6): 1371. 27 May 2020

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A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation.
Gaertner, B., van Heesch, S., Schneider-Lunitz, V., Schulz, J.F., Witte, F., Blachut, S., Nguyen, S., Wong, R., Matta, I., Hübner, N. and Sander, M.
eLife 9 : e58659. 3 August 2020

Open Source ImmGen: network perspective on metabolic diversity among mononuclear phagocytes.
Gainullina, A., Huang, L.H., Todorov, H., Kim, K., Yng, L.S., Kent, A., Jia, B., Seddu, K., Krchma, K., Wu, J., Crozat, K., Tomasello, E., Narang, V., Dress, R., See, P., Scott, C., Gibbings, S., Bajpai, G., Desai, J.V., Maier, B., This, S., Wang, P., Aguilar, S.V., Poupel, L., Dussaud, S., Zhou, T.A., Angeli, V., Blander, J.M., Choi, K., Dalod, M., Dzhagalov, I., Gautier, E.L., Jakubzick, C., Lavine, K., Lionakis, M.S., Paidassi, H., Sieweke, M.H., Ginhoux, Fl., Guilliams, M., Benoist, C., Merad, M., Randolph, G.J., Sergushichev, A. and Artyomov, M.N.
bioRxiv : 2020.07.15.204388. 16 July 2020

A conserved noncoding locus regulates random monoallelic Xist expression across a topological boundary.
Galupa, R., Nora, E.P., Worsley-Hunt, R., Picard, C., Gard, C., van Bemmel, J.G., Servant, N., Zhan, Y., El Marjou, F., Johanneau, C., Diabangouaya, P., Le Saux, A., Lameiras, S., Pipoli da Fonseca, J., Loos, F., Gribnau, J., Baulande, S., Ohler, U., Giorgetti, L. and Heard, E.
Molecular Cell 77 (2): 352-367. 16 January 2020

Mechanistic basis for motor-driven membrane constriction by dynamin.
Ganichkin, O., Vancraenenbroeck, R., Rosenblum, G., Hofmann, H., Mikhailov, A.S., Daumke, O. and Noel, J.K.
bioRxiv : 2020.09.10.289546. 11 September 2020

Exploiting a PAX3-FOXO1-induced synthetic lethal ATR dependency for rhabdomyosarcoma therapy.
García, H.D., Bei, Y., von Stebut, J., Ibáñez, G., Imami, K., Gürgen, D., Rolff, J., Helmsauer, K., Timme, N., Bardinet, V., Chamorro González, R., MacArthur, I.C., Pusch, F.F., Chen, C.Y., Schulz, J., Wengner, A.M., Furth, C., Lala, B., Eggert, A., Seifert, G., Hundsoerfer, P., Kirchner, M., Mertins, P., Selbach, M., Lissat, A., Schulte, J.H., Haase, K., Scheer, M., Ortiz, M.V. and Henssen, A.G.
bioRxiv : 2020.12.04.411413. 2020

The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II at pro-differentiation genes.
Garipler, G., Lu, C., Morrissey, A., Lopez-Zepeda, L.S., Vidal, S.E., Aydin, B., Stadtfeld, M., Ohler, U., Mahony, S., Sanjana, N.E. and Mazzoni, E.O.
bioRxiv : 2020.11.23.391771. 23 November 2020

Genetic determinants of the humoral immune response in MS.
Gasperi, C., Andlauer, T.F.M., Keating, A., Knier, B., Klein, A., Pernpeintner, V., Lichtner, P., Gold, R., Zipp, F., Then Bergh, F., Stangel, M., Tumani, H., Wildemann, B., Wiendl, H., Bayas, A., Kümpfel, T., Zettl, U.K., Linker, R.A., Ziemann, U., Knop, M., Warnke, C., Friese, M.A., Paul, F., Tackenberg, B., Berthele, A. and Hemmer, B.
Neurology Neuroimmunology & Neuroinflammation 7 (5): e827. September 2020

Prognostic value of stress CMR perfusion imaging in patients with reduced left ventricular function.
Ge, Y., Antiochos, P., Steel, K., Bingham, S., Abdullah, S., Chen, Y.Y., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Shanbhag, S.M., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 13 (10): 2132-2145. October 2020

Cost-effectiveness analysis of stress cardiovascular magnetic resonance imaging for stable chest pain syndromes.
Ge, Y., Pandya, A., Steel, K., Bingham, S., Jerosch-Herold, M., Chen, Y.Y., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Shah, D.J., Raman, S.V., Ferrari, V.A., Schulz-Menger, J., Hachamovitch, R., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 13 (7): 1505-1517. July 2020

Lysine 4 of histone H3.3 is required for embryonic stem cell differentiation, histone enrichment at regulatory regions and transcription accuracy.
Gehre, M., Bunina, D., Sidoli, S., Lübke, M.J., Diaz, N., Trovato, M., Garcia, B.A., Zaugg, J.B. and Noh, K.M.
Nature Genetics 52 (3): 273-282. March 2020

Long-lived tumor-associated macrophages in glioma.
Georgieva, P.B., Mathivet, T., Alt, S., Giese, W., Riva, M., Balcer, M. and Gerhardt, H.
Neuro-Oncology Advances 2 (1): vdaa127. 9 November 2020

CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex.
Gerbracht, J.V., Boehm, V., Britto-Borges, T., Kallabis, S., Wiederstein, J.L., Ciriello, S., Aschemeier, D.U., Krüger, M., Frese, C.K., Altmüller, J., Dieterich, C. and Gehring, N.H.
Nucleic Acids Research 48 (15): 8626-8644. 4 September 2020

pH-dependent protonation of surface carboxylate groups in PsbO enables local buffering and triggers structural changes.
Gerland, L. M., Friedrich, D., Hopf, L., Donovan, E., Wallmann, A., Erdmann, N., Diehl, A., Bommer, M., Buzar, K., Ibrahim, M., Schmieder, P., Dobbek, H., Zouni, A., Bondar, A.-N., Dau, H. and Oschkinat, H.
ChemBioChem 21 (11): 1597-1604. 2 June 2020

Deep neural networks for interpreting RNA-binding protein target preferences.
Ghanbari, M. and Ohler, U.
Genome Research 30 (2): 214-226. February 2020

Notch1 in cancer therapy: possible clinical implications and challenges.
Gharaibeh, L., Elmadany, N., Alwosaibai, K. and Alshaer, W.
Molecular Pharmacology 98 (5): 559-576. 1 November 2020

Prostaglandin E(2) in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8(+) T cells.
Gierlich, P., Lex, V., Technau, A., Keupp, A., Morper, L., Glunz, A., Sennholz, H., Rachor, J., Sauer, S., Marcu, A., Grigoleit, G.U., Wölfl, M., Schlegel, P.G. and Eyrich, M.
Cancer Immunology Immunotherapy 69 (6): 1029-1042. June 2020

Cxcl10(+) monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation.
Giladi, A., Wagner, L.K., Li, H., Dörr, D., Medaglia, C., Paul, F., Shemer, A., Jung, S., Yona, S., Mack, M., Leutz, A., Amit, I. and Mildner, A.
Nature Immunology 21 (5): 525-534. May 2020

GPSeq reveals the radial organization of chromatin in the cell nucleus.
Girelli, G., Custodio, J., Kallas, T., Agostini, F., Wernersson, E., Spanjaard, B., Mota, A., Kolbeinsdottir, S., Gelali, E., Crosetto, N. and Bienko, M.
Nature Biotechnology 38 (10): 1184-1193. October 2020

Frequency of autoimmune disorders and autoantibodies in European patients with neuromyelitis optica spectrum disorders.
Gkaniatsou, T., Papadopoulou, A., Paul, F., Brandt, A.U. and Oertel, F.C.
Acta Neurologica Belgica 120 (1): 223-225. February 2020

Lymphoma angiogenesis is orchestrated by noncanonical signaling pathways.
Gloger, M., Menzel, L., Grau, M., Vion, A.C., Anagnostopoulos, I., Zapukhlyak, M., Gerlach, K., Kammertöns, T., Hehlgans, T., Zschummel, M., Lenz, G., Gerhardt, H., Höpken, U.E. and Rehm, A.
Cancer Research 80 (6): 1316-1329. March 2020

Effects of hemodialysis on blood fatty acids.
Gollasch, B., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 8 (2): e14332. January 2020

Effects of hemodialysis on plasma oxylipins.
Gollasch, B., Wu, G., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 8 (12): e14447. June 2020

Hemodialysis and erythrocyte epoxy fatty acids.
Gollasch, B., Wu, G., Liu, T., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 8 (20): e14601. October 2020

Editorial: Renal hypertension at the crossroads: theoretical, experimental and clinical aspects.
Gollasch, M. and Hoyer, J.
Frontiers in Medicine 7 : 49. 19 February 2020

Type I phosphatidylinositol-4-phosphate 5-kinase α and γ play a key role in targeting HIV-1 Pr55(Gag) to the plasma membrane.
Gonzales, B., de Rocquigny, H., Beziau, A., Durand, S., Burlaud-Gaillard, J., Lefebvre, A., Krull, S., Emond, P., Brand, D. and Piver, E.
Journal of Virology 94 (14): e00189. 1 July 2020

Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage.
Goulielmaki, E., Ioannidou, A., Tsekrekou, M., Stratigi, K., Poutakidou, I.K., Gkirtzimanaki, K., Aivaliotis, M., Evangelou, K., Topalis, P., Altmüller, J., Gorgoulis, V.G., Chatzinikolaou, G. and Garinis, G.A.
Nature Communications 11 (1): 42. 2 January 2020

Vampires and nurses are rated differently by younger and older adults - age-comparative norms of imageability and emotionality for about 2500 German nouns.
Grandy, T.H., Lindenberger, U. and Schmiedek, F.
Behavior Research Methods 52 (3): 980-989. June 2020

The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Grasedieck, S., Ruess, C., Krowiorz, K., Lux, S., Pochert, N., Schwarzer, A., Klusmann, J.H., Jongen-Lavrencic, M., Herold, T., Bullinger, L., Pollack, J.R., Rouhi, A. and Kuchenbauer, F.
Haematologica 105 (9): e448-e453. September 2020

So läuft es bei uns am Max-Delbrück-Centrum für Molekulare Medizin in der Helmhotz-Gemeinschaft.
Graßmann, H.
DUZ 20 (3): 62. 20 March 2020

Bradykinin B2 receptor signaling increases glucose uptake and oxidation: evidence and open questions.
Gregnani, M.F., Hungaro, T.G., Martins-Silva, L., Bader, M. and Araujo, R.C.
Frontiers in Pharmacology 11 : 1162. 4 August 2020

Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.
Greiner, J., Götz, M., Hofmann, S., Schrezenmeier, H., Wiesneth, M., Bullinger, L., Döhner, H. and Schneider, V.
Cancer Immunology Immunotherapy 69 (4): 629-640. April 2020

Ensuring center quality, proper patient selection and fair access to chimeric antigen receptor T-cell therapy: position statement of the Austrian CAR-T Cell Network.
Greinix, H.T., Attarbaschi, A., Girschikofsky, M., Greil, R., Holter, W., Neumeister, P., Peters, C., Petzer, A., Rudzki, J., Schlenke, P., Schmitt, C.A., Schwinger, W., Wolf, D., Worel, N. and Jaeger, U.
memo: Magazine of European Medical Oncology 13 (1): 27-31. March 2020

Early antihypertensive treatment and ischemia-induced acute kidney injury.
Greite, R., Derlin, K., Hensen, B., Thorenz, A., Rong, S., Chen, R., Hellms, S., Jang, M.S., Bräsen, J.H., Meier, M., Willenberg, I., Immenschuh, S., Haller, H., Luft, F.C., Panigrahy, D., Hwang, S.H., Hammock, B.D., Schebb, N.H. and Gueler, F.
American Journal of Physiology Renal Physiology 319 (4): F563-F570. October 2020

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.
Grinat, J., Heuberger, J., Vidal, R., Goveas, N., Kosel, F., Berenguer-Llergo, A., Kranz, A., Wulf-Goldenberg, A., Behrens, D., Melcher, B., Sauer, S., Vieth, M., Batlle, E., Stewart, A. and Birchmeier, W.
Nature Communications 11 (1): 6422. 21 December 2020

Mechanism of virus attenuation by codon pair deoptimization.
Groenke, N., Trimpert, J., Merz, S., Conradie, A.M., Wyler, E., Zhang, H., Hazapis, O.G., Rausch, S., Landthaler, M., Osterrieder, N. and Kunec, D.
Cell Reports 31 (4): 107586. 28 April 2020

Epigenetic regulator function through mouse gastrulation.
Grosswendt, S., Kretzmer, H., Smith, Z.D., Kumar, A.S., Hetzel, S., Wittler, L., Klages, S., Timmermann, B., Mukherji, S. and Meissner, A.
Nature 584 (7819): 102-108. 6 August 2020

The needle in the haystack - searching for genetic and epigenetic differences in monozygotic twins discordant for Tetralogy of Fallot.
Grunert, M., Appelt, S., Grossfeld, P. and Sperling, S.R.
Journal of Cardiovascular Development and Disease 7 (4): 55. 2 December 2020

Induced pluripotent stem cells of patients with Tetralogy of Fallot reveal transcriptional alterations in cardiomyocyte differentiation.
Grunert, M., Appelt, S., Schönhals, S., Mika, K., Cui, H., Cooper, A., Cyganek, L., Guan, K. and Sperling, S.R.
Scientific Reports 10 (1): 10921. 2 July 2020

Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Grunwald, S., Hopf, L.V.M., Bock-Bierbaum, T., Lally, C.C.M., Spahn, C.M.T. and Daumke, O.
Nature Communications 11 (1): 5506. 2 November 2020

Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue.
Grunwald, S.A., Popp, O., Haafke, S., Jedraszczak, N., Grieben, U., Saar, K., Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. and Spuler, S.
Scientific Reports 10 : 2158. 7 February 2020

Establishing a sensitive fluorescence-based quantification method for cyclic nucleotides.
Gruteser, N., Kohlhas, V., Balfanz, S., Franzen, A., Günther, A., Offenhäusser, A., Müller, F., Nikolaev, V., Lohse, M.J. and Baumann, A.
BMC Biotechnology 20 (1): 47. 27 August 2020

Sarcoma treatment in the era of molecular medicine.
Grünewald, T.G.P., Alonso, M., Avnet, S., Banito, A., Burdach, S., Cidre-Aranaz, F., Di Pompo, G., Distel, M., Dorado-Garcia, H., Garcia-Castro, J., González-González, L., Grigoriadis, A.E., Kasan, M., Koelsche, C., Krumbholz, M., Lecanda, F., Lemma, S., Longo, D.L., Madrigal-Esquivel, C., Morales-Molina, Á., Musa, J., Ohmura, S., Ory, B., Pereira-Silva, M., Perut, F., Rodriguez, R., Seeling, C., Al Shaaili, N., Shaabani, S., Shiavone, K., Sinha, S., Tomazou, E.M., Trautmann, M., Vela, M., Versleijen-Jonkers, Y.M.H., Visgauss, J., Zalacain, M., Schober, S.J., Lissat, A., English, W.R., Baldini, Ni. and Heymann, D.
EMBO Molecular Medicine 12 : e11131. 6 November 2020

Inefficient CAR-proximal signaling blunts antigen sensitivity.
Gudipati, V., Rydzek, J., Doel-Perez, I., Gonçalves, V.D.R., Scharf, L., Königsberger, S., Lobner, E., Kunert, R., Einsele, H., Stockinger, H., Hudecek, M. and Huppa, J.B.
Nature Immunology 21 (8): 848-856. August 2020

Saffron crudes and compounds restrict MACC1-dependent cell proliferation and migration of colorectal cancer cells.
Güllü, N., Kobelt, D., Brim, H., Rahman, S., Timm, L., Smith, J., Soleimani, A., Di Marco, S., Bisti, S., Ashktorab, H. and Stein, U.
Cells 9 (8): 1829. 3 August 2020

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A survey of travel behaviour among scientists in Germany and the potential for change.
Haage, V.
eLife 9 : e56765. 28 May 2020

Hematopoietic stem cells in health and disease - insights from single-cell multi-omic approaches.
Haas, S.
Current Stem Cell Reports 6 (3): 67-76. September 2020

Karzinogenese: Big Bang oder kontinuierliche Evolution?
Haase, K. and Schwarz, R.F.
BIOspektrum 26 (7): 718-720. November 2020

RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Haase, N., Foster, D.J., Cunningham, M.W., Bercher, J., Nguyen, T., Shulga-Morskaya, S., Milstein, S., Shaikh, S., Rollins, J., Golic, M., Herse, F., Kräker, K., Bendix, I., Serdar, M., Napieczynska, H., Heuser, A., Gellhaus, A., Thiele, K., Wallukat, G., Müller, D.N., LaMarca, B. and Dechend, R.
Journal of Clinical Investigation 130 (6): 2928-2942. 1 June 2020

CLIJ: GPU-accelerated image processing for everyone.
Haase, R., Royer, L.A., Steinbach, P., Schmidt, D., Dibrov, A., Schmidt, U., Weigert, M., Maghelli, N., Tomancak, P., Jug, F. and Myers, E.W.
Nature Methods 17 (1): 5-6. January 2020

The role of the gut microbiota and microbial metabolites in neuroinflammation.
Haase, S., Wilck, N., Haghikia, A., Gold, R., Mueller, D.N. and Linker, R.A.
European Journal of Immunology 50 (12): 1863-1870. December 2020

Long-term data on two sisters with C3GN due to an identical, homozygous CFH mutation and autoantibodies.
Hackl, A., Erger, F., Skerka, C., Wenzel, A., Tschernoster, N., Ehren, R., Burgmaier, K., Riehmer, V., Licht, C., Kirschfink, M., Weber, L.T., Altmueller, J., Zipfel, P.F. and Habbig, S.
Clinical Nephrology 94 (4): 197-206. October 2020

The effect of ageing and cerebral serotonin deficit on the activity of cytochrome P450 2D (CYP2D) in the brain and liver of male rats.
Haduch, A., Pukło, R., Alenina, N., Nikiforuk, A., Popik, P., Bader, M. and Daniel, W.A.
Neurochemistry International 141 : 104884. December 2020

Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains.
Haenig, C., Atias, N., Taylor, A.K., Mazza, A., Schaefer, M.H., Russ, J., Riechers, S.P., Jain, S., Coughlin, M., Fontaine, J.F., Freibaum, B.D., Brusendorf, L., Zenkner, M., Porras, P., Stroedicke, M., Schnoegl, S., Arnsburg, K., Boeddrich, A., Pigazzini, L., Heutink, P., Taylor, J.P., Kirstein, J., Andrade-Navarro, M.A., Sharan, R. and Wanker, E.E.
Cell Reports 32 (7): 108050. 18 August 2020

Serum amyloid A1 mediates myotube atrophy via Toll-like receptors.
Hahn, A., Kny, M., Pablo-Tortola, C., Todiras, M., Willenbrock, M., Schmidt, S., Schmoeckel, K., Jorde, I., Nowak, M., Jarosch, E., Sommer, T., Bröker, B.M., Felix, S.B., Scheidereit, C., Weber-Carstens, S., Butter, C., Luft, F.C. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 11 (1): 103-119. February 2020

Vascular cognitive impairment in the mouse reshapes visual, spatial network functional connectivity.
Hall, G.R., Boehm-Sturm, P., Dirnagl, U., Finke, C., Foddis, M., Harms, C., Koch, S.P., Kuchling, J., Madan, C.R., Mueller, S., Sassi, C., Sotiropoulos, S.N., Trueman, R.C., Wallis, M., Yildirim, F. and Farr, T.D.
bioRxiv : 2020.11.04.366294. 5 November 2020

Design, implementation, evaluation and application of a 32-channel radio frequency signal generator for thermal magnetic resonance based anti-cancer treatment.
Han, H., Eigentler, T.W., Wang, S., Kretov, E., Winter, L., Hoffmann, W., Grass, E. and Niendorf, T.
Cancers 12 (7): 1720. 28 June 2020

Intronic CRISPR repair in a preclinical model of Noonan syndrome-associated cardiomyopathy.
Hanses, U., Kleinsorge, M., Roos, L., Yigit, G., Li, Y., Barbarics, B., El-Battrawy, I., Lan, H., Tiburcy, M., Hindmarsh, R., Lenz, C., Salinas, G., Diecke, S., Müller, C., Adham, I., Altmüller, J., Nürnberg, P., Paul, T., Zimmermann, W.H., Hasenfuss, G., Wollnik, B. and Cyganek, L.
Circulation 142 (11): 1059-1076. 15 September 2020

Covid-19, ACE2, and the kidney.
Hardenberg, J.H. and Luft, F.C.
Acta Physiologica 230 (1): e13539. September 2020

Microbe-driven genotoxicity in gastrointestinal carcinogenesis.
Hartl, K. and Sigal, M.
International Journal of Molecular Sciences 21 (20): 7439. 2 October 2020

The mechanotransduction protein STOML3 is required for functional plasticity following peripheral nerve regeneration.
Haseleu, J., Walcher, J. and Lewin, G.R.
bioRxiv : 2020.11.10.367748. 10 November 2020

Selbst berichtete Infektionen in der NAKO Gesundheitsstudie - Einordnung in die gegenwärtige Forschungslandschaft [Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape].
Hassenstein, M.J., Aarabi, G., Ahnert, P., Becher, H., Franzke, C.-W., Fricke, J., Krause, G., Glöckner, S., Gottschick, C., Karch, A., Kemmling, Y., Kerrinnes, T., Lange, B., Mikolajczyk, R., Nieters, A., Ott, J.J., Ahrens, W., Berger, K., Meinke-Franze, C., Gastell, S., Günther, K., Greiser, K.H., Holleczek, B., Horn, J., Jaeschke, L., Jagodzinski, A., Jansen, L., Jochem, C., Jöckel, K.H., Kaaks, R., Krist, L., Kuß, O., Langer, S., Legath, N., Leitzmann, M., Lieb, W., Loeffler, M., Mangold, N., Michels, K.B., Meisinger, C., Obi, N., Pischon, T., Schikowski, T., Schipf, S., Schulze, M.B., Stang, A., Waniek, S., Wirkner, K., Willich, S.N. and Castell, S.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (4): 404-414. April 2020

High-risk additional chromosomal abnormalities at low blast counts herald death by CML.
Hehlmann, R., Voskanyan, A., Lauseker, M., Pfirrmann, M., Kalmanti, L., Rinaldetti, S., Kohlbrenner, K., Haferlach, C., Schlegelberger, B., Fabarius, A., Seifarth, W., Spieß, B., Wuchter, P., Krause, S., Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Burchert, A., Brümmendorf, T.H., Hasford, J., Hochhaus, A., Saußele, S. and Baccarani, M.
Leukemia 34 (8): 2074-2086. August 2020

Transdiagnostic hippocampal damage patterns in neuroimmunological disorders.
Heine, J., Prüß, H., Scheel, M., Brandt, A.U., Gold, S.M., Bartsch, T., Paul, F. and Finke, C.
NeuroImage: Clinical 28 : 102515. 2020

Symmetry in nucleic-acid double helices.
Heinemann, U. and Roske, Y.
Symmetry 12 (5): 737. 5 May 2020

Radiological, chemical, and pharmacological cholinergic system parameters and neurocognitive disorders in older presurgical adults.
Heinrich, M., Müller, A., Lammers-Lietz, F., Borchers, F., Mörgeli, R., Kruppa, J., Zacharias, N., Winterer, G., Slooter, A.J.C. and Spies, C.D.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences 76 (6): 1029-1036. June 2020

Addiction Research Consortium: losing and regaining control over drug intake (ReCoDe) - from trajectories to mechanisms and interventions.
Heinz, A., Kiefer, F., Smolka, M.N., Endrass, T., Beste, C., Beck, A., Liu, S., Genauck, A., Romund, L., Banaschewski, T., Bermpohl, F., Deserno, L., Dolan, R.J., Durstewitz, D., Ebner-Priemer, U., Flor, H., Hansson, A.C., Heim, C., Hermann, D., Kiebel, S., Kirsch, P., Kirschbaum, C., Koppe, G., Marxen, M., Meyer-Lindenberg, A., Nagel, W.E., Noori, H.R., Pilhatsch, M., Priller, J., Rietschel, M., Romanczuk-Seiferth, N., Schlagenhauf, F., Sommer, W.H., Stallkamp, J., Ströhle, A., Stock, A.K., Winterer, G., Winter, C., Walter, H., Witt, S., Vollstädt-Klein, S., Rapp, M.A., Tost, H. and Spanagel, R.
Addiction Biology 25 (2): e12866. March 2020

Left ventricular dysfunction in heart failure with preserved ejection fraction-molecular mechanisms and impact on right ventricular function.
Heinzel, F.R., Hegemann, N., Hohendanner, F., Primessnig, U., Grune, J., Blaschke, F., de Boer, R.A., Pieske, B., Schiattarella, G.G. and Kuebler, W.M.
Cardiovascular Diagnosis and Therapy 10 (5): 1541-1560. October 2020

Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study.
Heitmann, H., Haller, B., Tiemann, L., Mühlau, M., Berthele, A., Tölle, T.R., Salmen, A., Ambrosius, B., Bayas, A., Asseyer, S., Hartung, H.P., Heesen, C., Stangel, M., Wildemann, B., Haars, S., Groppa, S., Luessi, F., Kümpfel, T., Nischwitz, S., Meuth, S.G., Klotz, L., Linker, R.A., Zettl, U.K., Ziemann, U., Tumani, H., Tackenberg, B., Zipp, F., Wiendl, H., Gold, R., Hemmer, B. and Ploner, M.
Pain 161 (4): 787-796. April 2020

Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state.
Helker, C.S.M., Eberlein, J., Wilhelm, K., Sugino, T., Malchow, J., Schuermann, A., Baumeister, S., Kwon, H.B., Maischein, H.M., Potente, M., Herzog, W. and Stainier, D.Y.R.
eLife 9 : e55589. 21 September 2020

Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma.
Helmsauer, K., Valieva, M.E., Ali, S., Chamorro Gonzalez, R., Schöpflin, R., Röefzaad, C., Bei, Y., Dorado Garcia, H., Rodriguez-Fos, E., Puiggròs, M., Kasack, K., Haase, K., Keskeny, C., Chen, C.Y., Kuschel, L.P., Euskirchen, P., Heinrich, V., Robson, M.I., Rosswog, C., Toedling, J., Szymansky, A., Hertwig, F., Fischer, M., Torrents, D., Eggert, A., Schulte, J.H., Mundlos, S., Henssen, A.G. and Koche, R.P.
Nature Communications 11 (1): 5823. 16 November 2020

CXCR4-targeted PET imaging of central nervous system B-cell lymphoma.
Herhaus, P., Lipkova, J., Lammer, F., Yakushev, I., Vag, T., Slotta-Huspenina, J., Habringer, S., Lapa, C., Pukrop, T., Hellwig, D., Wiestler, B., Buck, A.K., Deckert, M., Wester, H.J., Bassermann, F., Schwaiger, M., Weber, W.A., Menze, B. and Keller, U.
Journal of Nuclear Medicine 61 (12): 1765-1771. 1 December 2020

α2A-adrenoceptors modulate renal sympathetic neurotransmission and protect against hypertensive kidney disease.
Hering, L., Rahman, M., Hoch, H., Markó, L., Yang, G., Reil, A., Yakoub, M., Gupta, V., Potthoff, S.A., Vonend, O., Ralph, D.L., Gurley, S.B., McDonough, A.A., Rump, L.C. and Stegbauer, J.
Journal of the American Society of Nephrology 31 (4): 783-798. April 2020

Viral cGAMP nuclease reveals the essential role of DNA sensing in protection against acute lethal virus infection.
Hernáez, B., Alonso, G., Georgana, I., El-Jesr, M., Martín, R., Shair, K.H.Y., Fischer, C., Sauer, S., Maluquer de Motes, C. and Alcamí, A.
Science Advances 6 (38): eabb4565. 18 September 2020

Final results of a phase I/II trial of the combination Bendamustine and Rituximab with Temsirolimus (BeRT) in relapsed mantle cell lymphoma and follicular lymphoma.
Hess, G., Wagner, K., Keller, U., La Rosee, P., Atta, J., Hübel, K., Lerchenmueller, C., Schoendube, D., Witzens-Harig, M., Ruckes, C., Medler, C., van Oordt, C., Klapper, W., Theobald, M. and Dreyling, M.
HemaSphere 4 (3): e398. June 2020

Association for European Paediatric and Congenital Cardiology recommendations for basic training in paediatric and congenital cardiology 2020.
Heying, R., Albert, D.C., Voges, I., Sendzikaite, S., Sarquella-Brugada, G., Pluchinotta, F., Brzezinska-Rajszys, G., Stein, J.I. and Milanesi, O.
Cardiology in the Young 30 (11): 1572-1587. November 2020

BRAVE-NET: fully automated arterial brain vessel segmentation in patients with cerebrovascular disease.
Hilbert, A., Madai, V.I., Akay, E.M., Aydin, O.U., Behland, J., Sobesky, J., Galinovic, I., Khalil, A.A., Taha, A.A.A., Wuerfel, J., Dusek, P., Niendorf, T., Fiebach, J.B., Frey, D. and Livne, M.
Frontiers in Artificial Intelligence 3 : 552258. 25 September 2020

Comprehensive analysis of translation from overexpressed circular RNAs reveals pervasive translation from linear transcripts.
Ho-Xuan, H., Glažar, P., Latini, C., Heizler, K., Haase, J., Hett, R., Anders, M., Weichmann, F., Bruckmann, A., Van den Berg, D., Hüttelmaier, S., Rajewsky, N., Hackl, C. and Meister, G.
Nucleic Acids Research 48 (18): 10368-10382. 9 October 2020

Comparative efficacy of targeted therapies in patients with non-small cell lung cancer: a network meta-analysis of clinical trials.
Hoang, T., Myung, S.K., Pham, T.T., Kim, J. and Ju, W.
Journal of Clinical Medicine 9 (4): 1063. April 2020

Efficacy of crizotinib, ceritinib, and alectinib in ALK-positive non-small cell lung cancer treatment: a meta-analysis of clinical trials.
Hoang, T., Myung, S.K., Pham, T.T. and Park, B.
Cancers 12 (3): 526. 25 February 2020

Evolution of pulmonary hypertension during severe sustained hypoxia.
Hoffmann, F., Limper, U., Zaha, V.G., Reuter, H., Zange, L., Schulz-Menger, J., Hein, M., Baldus, S., Levine, B.D., Jordan, J. and Tank, J.
Circulation 141 (18): 1504-1506. 5 May 2020

FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease.
Hoffmann, S., Pentakota, S., Mund, A., Haahr, P., Coscia, F., Gallo, M., Mann, M., Taylor, N.M. and Mailand, N.
EMBO Reports 21 (10): e50662. 5 October 2020

MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma.
Hohmann, T., Hohmann, U., Kolbe, M.R., Dahlmann, M., Kobelt, D., Stein, U. and Dehghani, F.
Cell Communication and Signaling 18 (1): 85. 5 June 2020

Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling.
Hollenhorst, M.I., Jurastow, I., Nandigama, R., Appenzeller, S., Li, L., Vogel, J., Wiederhold, S., Althaus, M., Empting, M., Altmüller, J., Hirsch, A.K.H., Flockerzi, V., Canning, B.J., Saliba, A.E. and Krasteva-Christ, G.
FASEB Journal 34 (1): 316-332. January 2020

Design und Qualitätskontrolle der zahnmedizinischen Untersuchung in der NAKO Gesundheitsstudie [Design and quality control of the oral health status examination in the German National Cohort (GNC)].
Holtfreter, B., Samietz, S., Hertrampf, K., Aarabi, G., Hagenfeld, D., Kim, T.S., Kocher, T., Koos, B., Schmitter, M., Ahrens, W., Alwers, E., Becher, H., Berger, K., Brenner, H., Damms-Machado, A., Ebert, N., Fischer, B., Franzke, C.W., Frölich, S., Greiser, H., Gies, A., Günther, K., Hassan, L., Hoffmann, W., Jaeschke, L., Keil, T., Kemmling, Y., Krause, G., Krist, L., Legath, N., Lieb, W., Leitzmann, M., Linseisen, J., Loeffler, M., Meinke-Franze, C., Michels, K.B., Mikolajczyk, R., Obi, N., Peters, A., Pischon, T., Schipf, S., Schmidt, B., Völzke, H., Waniek, S., Wigmann, C., Wirkner, K., Schmidt, C.O., Kühnisch, J. and Rupf, S.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (4): 426-438. April 2020

Digestiflow: from BCL to FASTQ with ease.
Holtgrewe, M., Messerschmidt, C., Nieminen, M. and Beule, D.
Bioinformatics 36 (6): 1983-1985. 15 March 2020

VarFish: comprehensive DNA variant analysis for diagnostics and research.
Holtgrewe, M., Stolpe, O., Nieminen, M., Mundlos, S., Knaus, A., Kornak, U., Seelow, D., Segebrecht, L., Spielmann, M., Fischer-Zirnsak, B., Boschann, F., Scholl, U., Ehmke, N. and Beule, D.
Nucleic Acids Research 48 (W1): W162-W169. 2 July 2020

VarFish - Collaborative and comprehensive variant analysis for diagnosis and research.
Holtgrewe, M., Stolpe, O., Nieminen, M., Mundlos, S., Knaus, A., Kornak, U., Seelow, D., Segebrecht, L., Spielmann, M., Fischer-Zirnsak, B., Boschann, F., Scholl, U., Ehmke, N. and Beule, D.
bioRxiv : 2020.01.27.921965. 31 January 2020

Ligand-specific allosteric coupling controls G-protein-coupled receptor signaling.
Holze, J., Bermudez, M., Pfeil, E.M., Kauk, M., Bödefeld, T., Irmen, M., Matera, C., Dallanoce, C., De Amici, M., Holzgrabe, U., König, G.M., Tränkle, C., Wolber, G., Schrage, R., Mohr, K., Hoffmann, C., Kostenis, E. and Bock, A.
ACS Pharmacology & Translational Science 3 (5): 859-867. 9 October 2020

Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly.
Hong, M., Christ, A., Christa, A., Willnow, T.E. and Krauss, R.S.
eLife 9 : e60351. 2 September 2020

Cdon mutation and fetal alcohol converge on nodal signaling in a gene-environment interaction model of holoprosencephaly.
Hong, M., Christ, A., Christa, A., Willnow, T.E. and Krauss, R.S.
bioRxiv : 2020.04.30.070870. 1 May 2020

Authentication of primary murine cell lines by a microfluidics-based lab-on-chip system.
Hong, Y., Singh, N., Bamopoulos, S., Gjerga, E., Schmalbrock, L.K., Balabanian, K., Schick, M., Keller, U. and Wirth, M.
Biomedicines 8 (12): 590. 9 December 2020

Epidemiology of neuromyelitis optica spectrum disorder and its prevalence and incidence worldwide.
Hor, J.Y., Asgari, N., Nakashima, I., Broadley, S.A., Leite, M.I., Kissani, N., Jacob, A., Marignier, R., Weinshenker, B.G., Paul, F., Pittock, S.J., Palace, J., Wingerchuk, D.M., Behne, J.M., Yeaman, M.R. and Fujihara, K.
Frontiers in Neurology 11 : 501. 26 June 2020

A multi-modal virtual reality treadmill intervention for enhancing mobility and cognitive function in people with multiple sclerosis: protocol for a randomized controlled trial.
Hsieh, K.L., Mirelman, A., Shema-Shiratzky, S., Galperin, I., Regev, K., Shen, S., Schmitz-Hübsch, T., Karni, A., Paul, F., Devos, H., Sosnoff, J.J. and Hausdorff, J.M.
Contemporary Clinical Trials 97 : 106122. October 2020

Down-regulation of Aquaporin-1 mediates a microglial phenotype switch affecting glioma growth.
Hu, F., Huang, Y., Semtner, M., Zhao, K., Tan, Z., Dzaye, O., Kettenmann, H., Shu, K. and Lei, T.
Experimental Cell Research 396 (2): 112323. 15 November 2020

FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells.
Hu, J.L., Liang, H., Zhang, H., Yang, M.Z., Sun, W., Zhang, P., Luo, L., Feng, J.X., Bai, H., Liu, F., Zhang, T., Yang, J.Y., Gao, Q., Long, Y., Ma, X.Y., Chen, Y., Zhong, Q., Yu, B., Liao, S., Wang, Y., Zhao, Y., Zeng, M.S., Cao, N., Wang, J., Chen, W., Yang, H.T. and Gao, S.
Nucleic Acids Research 48 (5): 2733-2748. 18 March 2020

Integrated proteomic and glycoproteomic characterization of human high-grade serous ovarian carcinoma.
Hu, Y., Pan, J., Shah, P., Ao, M., Thomas, S.N., Liu, Y., Chen, L., Schnaubelt, M., Clark, D.J., Rodriguez, H., Boja, E.S., Hiltke, T., Kinsinger, C.R., Rodland, K.D., Li, Q.K., Qian, J., Zhang, Z., Chan, D.W. and Zhang, H.
Cell Reports 33 (3): 108276. 20 October 2020

CTCF mediates dosage and sequence-context-dependent transcriptional insulation through formation of local chromatin domains.
Huang, H., Zhu, Q., Jussila, A., Han, Y., Bintu, B., Kern, C., Conte, M., Zhang, Y., Bianco, S., Chiariello, A.M., Yu, M., Hu, R., Juric, I., Hu, M., Nicodemi, M., Zhuang, X. and Ren, B.
bioRxiv : 2020.07.07.192526. 8 July 2020

MEK inhibitor trametinib attenuates neuroinflammation and cognitive deficits following traumatic brain injury in mice.
Huang, Y., Li, Q., Tian, H., Yao, X., Bakina, O., Zhang, H., Lei, T. and Hu, F.
American Journal of Translational Research 12 (10): 6351-6365. 15 October 2020

Synergistic toll-like receptor 3/9 signaling affects properties and impairs glioma-promoting activity of microglia.
Huang, Y., Zhang, Q., Lubas, M., Yuan, Y., Yalcin, F., Efe, I.E., Xia, P., Motta, E., Buonfiglioli, A., Lehnardt, S., Dzaye, O., Flueh, C., Synowitz, M., Hu, Feng and Kettenmann, H.
Journal of Neuroscience 40 (33): 6428-6443. 12 August 2020

Local and central evaluation of HER2 positivity and clinical outcome in advanced gastric and gastroesophageal cancer: results from the AGMT GASTRIC-5 Registry.
Huemer, F., Weiss, L., Regitnig, P., Winder, T., Hartmann, B., Thaler, J., Piringer, G., Schmitt, C.A., Eisterer, W., Gänzer, H., Wüstner, Al., Andel, J., Jagdt, B., Ulmer, H., Greil, R. and Wöll, E.
Journal of Clinical Medicine 9 (4): 935. 29 March 2020

The International Virus Bioinformatics Meeting 2020.
Hufsky, F., Beerenwinkel, N., Meyer, I.M., Roux, S., Cook, G.M., Kinsella, C.M., Lamkiewicz, K., Marquet, M., Nieuwenhuijse, D.F., Olendraite, I., Paraskevopoulou, S., Young, F., Dijkman, R., Ibrahim, B., Kelly, J., Le Mercier, P., Marz, M., Ramette, A. and Thiel, V.
Viruses 12 (12): 1398. 6 December 2020

Emotional experience in patients with clinically isolated syndrome and early multiple sclerosis.
Hälbig, T.D., Wüstenberg, T., Giess, R.M., Kunte, H., Bellmann-Strobl, J., Ruprecht, K. and Paul, F.
European Journal of Neurology 27 (8): 1537-1545. August 2020

Rescue of oxytocin response and social behaviour in a mouse model of autism.
Hörnberg, H., Pérez-Garci, E., Schreiner, D., Hatstatt-Burklé, L., Magara, F., Baudouin, S., Matter, A., Nacro, K., Pecho-Vrieseling, E. and Scheiffele, P.
Nature 584 (7820): 252-256. 13 August 2020

I

Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury.
Ifuku, M., Hinkelmann, L., Kuhrt, L.D., Efe, I.E., Kumbol, V., Buonfiglioli, A., Krüger, C., Jordan, P., Fulde, M., Noda, M., Kettenmann, H. and Lehnardt, S.
Acta Neuropathologica Communications 8 (1): 159. 10 September 2020

Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.
Ihantola, T., Di Bucchianico, S., Happo, M., Ihalainen, M., Uski, O., Bauer, S., Kuuspalo, K., Sippula, O., Tissari, J., Oeder, S., Hartikainen, A., Rönkkö, T.J., Martikainen, M.V., Huttunen, K., Vartiainen, P., Suhonen, H., Kortelainen, M., Lamberg, H., Leskinen, A., Sklorz, M., Michalke, B., Dilger, M., Weiss, C., Dittmar, G., Beckers, J., Irmler, M., Buters, J., Candeias, J., Czech, H., Yli-Pirilä, P., Abbaszade, G., Jakobi, G., Orasche, J., Schnelle-Kreis, J., Kanashova, T., Karg, E., Streibel, T., Passig, J., Hakkarainen, H., Jokiniemi, J., Zimmermann, R., Hirvonen, M.R. and Jalava, P.I.
Particle and Fibre Toxicology 17 (1): 27. 15 June 2020

Investigation of visual system involvement in spinocerebellar ataxia type 14.
Ihl, T., Kadas, E.M., Oberwahrenbrock, T., Endres, M., Klockgether, T., Schroeter, J., Brandt, A.U., Paul, F., Minnerop, M., Doss, S., Schmitz-Hübsch, T. and Zimmermann, H.G.
Cerebellum 19 (4): 469-482. August 2020

Impact of chronic kidney disease on platelet aggregation in patients with acute coronary syndrome.
Ilardi, F., Gargiulo, G., Paolillo, R., Ferrone, M., Cimino, S., Giugliano, G., Schiattarella, G.G., Verde, N., Stabile, E., Perrino, C., Cirillo, P., Coscioni, E., Morisco, C. and Esposito, G.
Journal of Cardiovascular Medicine 21 (9): 660-666. September 2020

Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia.
In't Hout, F.E.M., Gerritsen, M., Bullinger, L., Van der Reijden, B.A., Huls, G., Vellenga, E. and Jansen, J.H.
Haematologica 105 (9): e454-457. 1 September 2020

Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease.
Izarzugaza, J.M.G., Ellesøe, S.G., Doganli, C., Ehlers, N.S., Dalgaard, M.D., Audain, E., Dombrowsky, G., Banasik, K., Sifrim, A., Wilsdon, A., Thienpont, B., Breckpot, J., Gewillig, M., Brook, J.D., Hitz, M.P., Larsen, L.A. and Brunak, S.
Genome Medicine 12 (1): 76. 28 August 2020

Pharmacological characterization of the stick insect Carausius morosus allatostatin-C receptor with its endogenous agonist.
Işbilir, A., Duan Sahbaz, B., Tuncgenc, G., Bünemann, M., Lohse, M.J. and Birgül-Iyison, N.
ACS Omega 5 (50): 32183-32194. 22 December 2020

Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists.
Işbilir, A., Möller, J., Arimont, M., Bobkov, V., Perpiñá-Viciano, C., Hoffmann, C., Inoue, A., Heukers, R., de Graaf, C., Smit, M.J., Annibale, P. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 117 (46): 29144-29154. 17 November 2020

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Factors associated with habitual time spent in different physical activity intensities using multiday accelerometry.
Jaeschke, L., Steinbrecher, A., Boeing, H., Gastell, S., Ahrens, W., Berger, K., Brenner, H., Ebert, N., Fischer, B., Greiser, K.H., Hoffmann, W., Jöckel, K.H., Kaaks, R., Keil, T., Kemmling, Y., Kluttig, A., Krist, L., Leitzmann, M., Lieb, W., Linseisen, J., Löffler, M., Michels, K.B., Obi, N., Peters, A., Schipf, S., Schmidt, B., Zinkhan, M. and Pischon, T.
Scientific Reports 10 : 774. 21 January 2020

Erfassung selbst berichteter kardiovaskulärer und metabolischer Erkrankungen in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse [Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): methods and initial results].
Jaeschke, L., Steinbrecher, A., Greiser, K.H., Dörr, M., Buck, T., Linseisen, J., Meisinger, C., Ahrens, W., Becher, H., Berger, K., Braun, B., Brenner, H., Castell, S., Fischer, B., Franzke, C.W., Gastell, S., Günther, K., Hoffmann, W., Holleczek, B., Jagodzinski, A., Kaaks, R., Kluttig, A., Krause, G., Krist, L., Kuß, O., Lehnich, A.T., Leitzmann, M., Lieb, W., Löffler, M., Michels, K.B., Mikolajczyk, R., Peters, A., Schikowski, T., Schipf, S., Schmidt, B., Schulze, M., Völzke, H., Willich, S.N. and Pischon, T.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (4): 439-451. April 2020

Association of body surface scanner-based abdominal volume with parameters of the Metabolic Syndrome and comparison with manually measured waist circumference.
Jaeschke, L., Steinbrecher, A., Hansen, G., Sommer, S., Adler, C., Janke, J. and Pischon, T.
Scientific Reports 10 (1): 9324. 9 June 2020

Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.
Jahn, N., Terzer, T., Sträng, E., Dolnik, A., Cocciardi, S., Panina, E., Corbacioglu, A., Herzig, J., Weber, D., Schrade, A., Götze, K., Schröder, T., Lübbert, M., Wellnitz, D., Koller, E., Schlenk, R.F., Gaidzik, V.I., Paschka, P., Rücker, F.G., Heuser, M., Thol, F., Ganser, A., Benner, A., Döhner, H., Bullinger, L. and Döhner, K.
Blood Advances 4 (24): 6342-6352. 22 December 2020

Cbl-Associated Protein CAP contributes to correct formation and robust function of the Drosophila heart tube.
Jammrath, J., Reim, I. and Saumweber, H.
PLoS ONE 15 (5): e0233719. 29 May 2020

A randomized open label phase-II clinical trial with or without infusion of plasma from subjects after convalescence of SARS-CoV-2 infection in high-risk patients with confirmed severe SARS-CoV-2 disease (RECOVER): a structured summary of a study protocol for a randomised controlled trial.
Janssen, M., Schäkel, U., Djuka Fokou, C., Krisam, J., Stermann, J., Kriegsmann, K., Haberbosch, I., Novotny, J.P., Weber, S., Vehreschild, M., Bornhäuser, M., Bullinger, L., Schmitt, M., Liebregts, T., Dreger, P., Lorenz, H.M., Plaszczyca, A., Bartenschlager, R., Müller, B., Kräusslich, H.G., Halama, N., Jäger, D., Schlenk, R.F., Leo, A., Meuer, S., Weigand, M.A., Motsch, J., Merle, U., Denkinger, C.M. and Müller-Tidow, C.
Trials 21 (1): 828. 6 October 2020

Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients.
Jarius, S., Lechner, C., Wendel, E.M., Baumann, M., Breu, M., Schimmel, M., Karenfort, M., Marina, A.D., Merkenschlager, A., Thiels, C., Blaschek, A., Salandin, M., Leiz, S., Leypoldt, F., Pschibul, A., Hackenberg, A., Hahn, A., Syrbe, S., Strautmanis, J., Häusler, M., Krieg, P., Eisenkölbl, A., Stoffels, J., Eckenweiler, M., Ayzenberg, I., Haas, J., Höftberger, R., Kleiter, I., Korporal-Kuhnke, M., Ringelstein, M., Ruprecht, K., Siebert, N., Schanda, K., Aktas, O., Paul, F., Reindl, M., Wildemann, B. and Rostásy, K.
Journal of Neuroinflammation 17 (1): 262. 3 September 2020

Neuromyelitis optica.
Jarius, S., Paul, F., Weinshenker, B.G., Levy, M., Kim, H.J. and Wildemann, B.
Nature Reviews Disease Primers 6 (1): 85. 22 October 2020

Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients.
Jarius, S., Pellkofer, H., Siebert, N., Korporal-Kuhnke, M., Hümmert, M.W., Ringelstein, M., Rommer, P.S., Ayzenberg, I., Ruprecht, K., Klotz, L., Asgari, N., Zrzavy, T., Höftberger, R., Tobia, R., Buttmann, M., Fechner, K., Schanda, K., Weber, M., Asseyer, S., Haas, J., Lechner, C., Kleiter, I., Aktas, O., Trebst, C., Rostasy, K., Reindl, M., Kümpfel, T., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 17 (1): 261. 3 September 2020

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.
Jayavelu, A.K., Schnöder, T.M., Perner, F., Herzog, C., Meiler, A., Krishnamoorthy, G., Huber, N., Mohr, J., Edelmann-Stephan, B., Austin, R., Brandt, S., Palandri, F., Schröder, N., Isermann, B., Edlich, F., Sinha, A.U., Ungelenk, M., Hübner, C.A., Zeiser, R., Rahmig, S., Waskow, C., Coldham, I., Ernst, T., Hochhaus, A., Jilg, S., Jost, P.J., Mullally, A., Bullinger, L., Mertens, P.R., Lane, S.W., Mann, M. and Heidel, F.H.
Nature 588 (7836): 157-163. 3 December 2020

Akzeptanz der Übertragung ärztlicher Tätigkeiten an Medizinische Fachangestellte: Ergebnisse einer repräsentativen Versichertenbefragung der Kassenärztlichen Bundesvereinigung [The acceptability of task-shifting from doctors to allied health professionals: results from a representative telephone survey of members of the National Association of Statutory Health Insurance Physicians].
Jedro, C., Holmberg, C., Tille, F., Widmann, J., Schneider, A., Stumm, J., Döpfmer, S., Kuhlmey, A. and Schnitzer, S.
Deutsches Aerzteblatt 117 (35-36): 583-590. 31 August 2020

The acceptability of task-shifting from doctors to allied health professionals - results from a representative telephone survey of members of the National Association of Statutory Health Insurance Physicians.
Jedro, C., Holmberg, C., Tille, F., Widmann, J., Schneider, A., Stumm, J., Döpfmer, S., Kuhlmey, A. and Schnitzer, S.
Deutsches Aerzteblatt International 117 (35-36): 583-590. 31 August 2020

Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions.
Jeuthe, S., Kemna, J., Kemna, C.P., Zocholl, D., Klopfleisch, R., Palme, R., Kirschbaum, C., Thoene-Reineke, C. and Kammertoens, T.
PLoS ONE 15 (9): e0239231. 30 September 2020

Impact of intercellular crosstalk between epidermal keratinocytes and dermal fibroblasts on skin homeostasis.
Jevtić, M., Löwa, A., Nováčková, A., Kováčik, A., Kaessmeyer, S., Erdmann, G., Vávrová, K. and Hedtrich, S.
Biochimica et Biophysica Acta - Molecular Cell Research 1867 (8): 118722. August 2020

Controlled release of therapeutics from thermoresponsive nanogels: a thermal magnetic resonance feasibility study.
Ji, Y., Winter, L., Navarro, L., Ku, M.C., Periquito, J.S., Pham, M., Hoffmann, W., Theune, L.E., Calderón, M. and Niendorf, T.
Cancers 12 (6): 1380. 27 May 2020

MCH neurons regulate permeability of the median eminence barrier.
Jiang, H., Gallet, S., Klemm, P., Scholl, P., Folz-Donahue, K., Altmüller, J., Alber, J., Heilinger, C., Kukat, C., Loyens, A., Müller-Fielitz, H., Sundaram, S., Schwaninger, M., Prevot, V. and Brüning, J.C.
Neuron 107 (2): 306-319. 22 July 2020

Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.
Jiang, S., Penack, O., Terzer, T., Schult, D., Majer-Lauterbach, J., Radujkovic, A., Blau, I.W., Bullinger, L., Müller-Tidow, C., Dreger, P. and Luft, T.
Haematologica 106 (2): 446-453. February 2020

The integrated RNA landscape of renal preconditioning against ischemia-reperfusion injury.
Johnsen, M., Kubacki, T., Yeroslaviz, A., Späth, M.R., Mörsdorf, J., Göbel, H., Bohl, K., Ignarski, M., Meharg, C., Habermann, B., Altmüller, J., Beyer, A., Benzing, T., Schermer, B., Burst, V. and Müller, R.U.
Journal of the American Society of Nephrology 31 (4): 716-730. April 2020

Optic chiasm measurements may be useful markers of anterior optic pathway degeneration in neuromyelitis optica spectrum disorders.
Juenger, V., Cooper, G., Chien, C., Chikermane, M., Oertel, F.C., Zimmermann, H., Ruprecht, K., Jarius, S., Siebert, N., Kuchling, J., Papadopoulou, A., Asseyer, S., Bellmann-Strobl, J., Paul, F., Brandt, A.U. and Scheel, M.
European Radiology 30 (9): 5048-5058. September 2020

Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes.
Jumaa, H., Caganova, M., McAllister, E.J., Hoenig, L., He, X., Saltukoglu, D., Brenker, K., Köhler, M., Leben, R., Hauser, A.E., Niesner, R., Rajewsky, K., Reth, M. and Jellusova, J.
Life Science Alliance 3 (6): e202000700. June 2020

Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1.
Jupp, B., Pitzoi, S., Petretto, E., Mar, A.C., Oliver, Y.P., Jordan, E.R., Taylor, S., Atanur, S.S., Srivastava, P.K., Saar, K., Hubner, N., Sommer, W.H., Staehlin, O., Spanagel, R., Robinson, E.S., Schumann, G., Moreno, M., Everitt, B.J., Robbins, T.W., Aitman, T.J. and Dalley, J.W.
Scientific Reports 10 (1): 6684. 21 April 2020

Mendelian randomization study on amino acid metabolism suggests tyrosine as causal trait for type 2 diabetes.
Jäger, S., Cuadrat, R., Wittenbecher, C., Floegel, A., Hoffmann, P., Prehn, C., Adamski, J., Pischon, T. and Schulze, M.B.
Nutrients 12 (12): 3890. 19 December 2020

Angiotensin-(1-7) receptor Mas deficiency does not exacerbate cardiac atrophy following high-level spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S., Alenina, N. and Bader, M.
Frontiers in Physiology 11 : 203. 12 March 2020

Angiotensin‐II receptor type Ia does not contribute to cardiac atrophy following high‐thoracic spinal cord injury in mice.
Järve, A., Qadri, F., Todiras, M., Schmolke, S. and Bader, M.
Experimental Physiology 105 (8): 1316-1325. 1 August 2020

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Identification of miR-21-5p and miR-210-3p serum levels as biomarkers for patients with papillary renal cell carcinoma: a multicenter analysis.
Kalogirou, C., Ellinger, J., Kristiansen, G., Hatzichristodoulou, G., Kübler, H., Kneitz, B., Busch, J. and Fendler, A.
Translational Andrology and Urology 9 (3): 1314-1322. June 2020

A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection.
Kaminski, M.M., Alcantar, M.A., Lape, I.T., Greensmith, R., Huske, A.C., Valeri, J.A., Marty, F.M., Klämbt, V., Azzi, J., Akalin, E., Riella, L.V. and Collins, J.J.
Nature Biomedical Engineering 4 (6): 601-609. June 2020

"Designer cytokines" targeting the tumor vasculature - think global and act local.
Kammertoens, T., Kemna, J. and Leisegang, M.
EMBO Molecular Medicine 12 (2): e11801. 7 February 2020

The dual role of serotonin in colorectal cancer.
Kannen, V., Bader, M., Sakita, J.Y., Uyemura, S.A. and Squire, J.A.
Trends in Endocrinology and Metabolism 31 (8): 611-625. August 2020

Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.
Kapp-Schwoerer, S., Weber, D., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Krönke, J., Theis, F., Rücker, F.G., Teleanu, M.V., Panina, E., Jahn, N., Herzig, J., Kubanek, L., Schrade, A., Göhring, G., Fiedler, W., Kindler, T, Schroeder, T., Mayer, K.T., Lübbert, M., Wattad, M., Götze, K.S., Horst, H.A., Koller, E., Wulf, G., Schleicher, J., Bentz, M., Krauter, J., Bullinger, L., Krzykalla, J., Benner, A., Schlenk, R.F., Thol, F., Heuser, M., Ganser, A., Döhner, H and Döhner, K.
Blood 136 (26): 3041-3050. 24 December 2020

Lungenfunktion in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse [Lung function in the German National Cohort: methods and initial results].
Karrasch, S., Peters, A., Meisinger, C., Ferland, M., Jaeschke, L., Pischon, T., Fricke, J., Keil, T., Gastell, S., Schulze, M., Brandes, M., Günther, K., Kuß, O., Schikowski, T., Emmel, C., Jöckel, K.H., Michels, K.B., Franzke, C.W., Langer, S., Mikolajczyk, R., Jagodzinski, A., Becher, H., Castell, S., Kemmling, Y., Waniek, S., Lieb, W., Wirkner, K., Loeffler, M., Greiser, K.H., Kaaks, R., Legath, N., Berger, K., Schipf, S., Hoffmann, W., Sedlmeier, A., Leitzmann, M., Brenner, H., Holleczek, B. and Schulz, H.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (3): 322-331. March 2020

Arterial elementary calcium signaling in aging.
Kassmann, M., Fan, G. and Gollasch, M.
Aging 12 (24): 24476-24478. 31 December 2020

Caplacizumab: frequent local skin reactions.
Kaufeld, J., Brinkkoetter, P.T., Schreiber, A., Jabs, W.J., Bieringer, M., Bruck, H., Menne, J. and Völker, L.A.
Annals of Hematology 100 (12): 3051-3052. December 2020

The CONDOR pipeline for simultaneous knockdown of multiple genes identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
Kazmierczak, M., Díaz, C.F., Ofenbauer, A. and Tursun, B.
bioRxiv : 2020.09.01.276972. 1 September 2020

Single cell RNA-sequencing-based analysis of CD4(+) T-cell subset-specific susceptibility to transcriptional modulation by HIV-1 latency-reversing agents.
Kazmierski, J., Postmus, D., Wyler, E., Fischer, C., Jansen, J., Meixenberger, K., Vitcetz, S.N., Sohn, M., Sauer, S., Bannert, N., Landthaler, M. and Goffinet, C.
bioRxiv : 2020.05.04.075119. 5 May 2020

Methods for mapping 3D chromosome architecture.
Kempfer, R. and Pombo, A.
Nature Reviews Genetics 21 (4): 207-226. April 2020

Assessment of diastolic dysfunction: comparison of different cardiovascular magnetic resonance techniques.
Kermer, J., Traber, J., Utz, W., Hennig, P., Menza, M., Jung, B., Greiser, A., Barckow, P., von Knobelsdorff-Brenkenhoff, F., Töpper, A., Blaszczyk, E. and Schulz-Menger, J.
ESC Heart Failure 7 (5): 2637-2649. October 2020

A single amino acid switch converts the sleeping beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming.
Kesselring, L., Miskey, C., Zuliani, C., Querques, I., Kapitonov, V., Laukó, A., Fehér, A., Palazzo, A., Diem, T., Lustig, J., Sebe, A., Wang, Y., Dinnyés, A., Izsvák, Z., Barabas, O. and Ivics, Z.
Nucleic Acids Research 48 (1): 316-331. 1 January 2020

Hyperkalzämie [Hypercalcemia].
Kettritz, R.
Deutsche Medizinische Wochenschrift 145 (3): 171-174. February 2020

Erkrankungen der Niere: Renale Vaskulopathien einschließlich Vaskulitiden.
Kettritz, R., Mertens, P.R. and Haubitz, M.
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CRISPLD1: a novel conserved target in the transition to human heart failure.
Khadjeh, S., Hindmarsh, V., Weber, F., Cyganek, L., Vidal, R.O., Torkieh, S., Streckfuss-Bömeke, K., Lbik, D., Tiburcy, M., Mohamed, B.A., Bonn, S., Toischer, K. and Hasenfuss, G.
Basic Research in Cardiology 115 (3): 27. 7 March 2020

AKI-Alerts.
Khadzhynov, D., Schmidt, D. and Schmidt-Ott, K.
Dialyse aktuell 24 (7): 265-269. September 2020

PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity.
Kim, H., Kim, H., Feng, Y., Li, Y., Tamiya, H., Tocci, S. and Ronai, Z.A.
Science Translational Medicine 12 (551): eaaz5683. 8 July 2020

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.
Kim, H., Nguyen, N.P., Turner, K., Wu, S., Gujar, A.D., Luebeck, J., Liu, J., Deshpande, V., Rajkumar, U., Namburi, S., Amin, S.B., Yi, E., Menghi, F., Schulte, J.H., Henssen, A.G., Chang, H.Y., Beck, C.R., Mischel, .S., Bafna, V. and Verhaak, R.G.W.
Nature Genetics 52 (9): 891-897. September 2020

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.
Kim, M., Franke, V., Brandt, B., Lowenstein, E.D., Schöwel, V., Spuler, S., Akalin, A. and Birchmeier, C.
Nature Communications 11 : 6375. 11 December 2020

Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation.
Kim, M., Zhang, Y. and Birchmeier, C.
bioRxiv : 2020.12.22.424062. 22 December 2020

Epigenetic reader BRD4 (Bromodomain-Containing Protein 4) governs nucleus-encoded mitochondrial transcriptome to regulate cardiac function.
Kim, S.Y., Zhang, X., Schiattarella, G.G., Altamirano, F., Ramos, T.A.R., French, K.M., Jiang, N., Szweda, P.A., Evers, B.M., May, H.I., Luo, X., Li, H., Szweda, L.I., Maracaja-Coutinho, V., Lavandero, S., Gillette, T.G. and Hill, J.A.
Circulation 142 (24): 2356-2370. 15 December 2020

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models.
Klems, A., van Rijssel, J., Ramms, A.S., Wild, R., Hammer, J., Merkel, M., Derenbach, L., Préau, L., Hinkel, R., Suarez-Martinez, I., Schulte-Merker, S., Vidal, R., Sauer, S., Kivelä, R., Alitalo, K., Kupatt, C., van Buul, J.D. and le Noble, F.
Nature Communications 11 (1): 5319. 21 October 2020

Combination of copanlisib with cetuximab improves tumor response in cetuximab-resistant patient-derived xenografts of head and neck cancer.
Klinghammer, K., Politz, O., Eder, T., Otto, R., Raguse, J.D., Albers, A., Kaufmann, A., Tinhofer, I., Hoffmann, J., Keller, U. and Keilholz, U.
Oncotarget 11 (41): 3688-3697. 13 October 2020

Messung der körperlichen Fitness in der NAKO Gesundheitsstudie – Methoden, Qualitätssicherung und erste deskriptive Ergebnisse [Measuring physical fitness in the German National Cohort-methods, quality assurance, and first descriptive results].
Kluttig, A., Zschocke, J., Haerting, J., Schmermund, A., Gastell, S., Steindorf, K., Herbolsheimer, F., Hillreiner, A., Jochem, C., Baumeister, S., Sprengeler, O., Pischon, T., Jaeschke, L., Michels, K.B., Krist, L., Greiser, H., Schmidt, G., Lieb, W., Waniek, S., Becher, H., Jagodzinski, A., Schipf, S., Völzke, H., Ahrens, W., Günther, K., Castell, S., Kemmling, Y., Legath, N., Berger, K., Keil, T., Fricke, J., Schulze, M.B., Loeffler, M., Wirkner, K., Kuß, O., Schikowski, T., Kalinowski, S., Stang, A., Kaaks, R., Damms Machado, A., Hoffmeister, M., Weber, B., Franzke, C.W., Thierry, S., Peters, A., Kartschmit, N., Mikolajczyk, R., Fischer, B., Leitzmann, M. and Brandes, M.
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (3): 312-321. March 2020

Treatment and mortality of hemophagocytic lymphohistiocytosis in adult critically ill patients: a systematic review with pooled analysis.
Knaak, C., Schuster, F.S., Nyvlt, P., Spies, C., Feinkohl, I., Beutel, G., Schenk, T., La Rosée, P., Janka, G., Brunkhorst, F.M., Keh, D. and Lachmann, G.
Critical Care Medicine 48 (11): e1137-e1146. November 2020

Small ones to fight a big problem-intervention of cancer metastasis by small molecules.
Kobelt, D., Dahlmann, M., Dumbani, M., Güllü, N., Kortüm, B., Vílchez, M.E.A., Stein, U. and Walther, W.
Cancers 12 (6): 1454. 3 June 2020

Pro-inflammatory TNF-α and IFN-γ promote tumor growth and metastasis via induction of MACC1.
Kobelt, D., Zhang, C., Clayton-Lucey, I.A., Glauben, R., Voss, C., Siegmund, B. and Stein, U.
Frontiers in Immunology 11 : 980. 27 May 2020

Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity.
Koch, C., Kuske, A., Joosse, S.A., Yigit, G., Sflomos, G., Thaler, S., Smit, D.J., Werner, S., Borgmann, K., Gärtner, S., Mossahebi Mohammadi, P., Battista, L., Cayrefourcq, L., Altmüller, J., Salinas-Riester, G., Raithatha, K., Zibat, A., Goy, Y., Ott, L., Bartkowiak, K., Tan, T.Z., Zhou, Q., Speicher, M.R., Müller, V., Gorges, T.M., Jücker, M., Thiery, J.P., Brisken, C., Riethdorf, S., Alix-Panabières, C. and Pantel, K.
EMBO Molecular Medicine 12 (9): e11908. 7 September 2020

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma.
Koche, R.P., Rodriguez-Fos, E., Helmsauer, K., Burkert, M., MacArthur, I.C., Maag, J., Chamorro, R., Munoz-Perez, N., Puiggròs, M., Dorado Garcia, H., Bei, Y., Röefzaad, C., Bardinet, V., Szymansky, A., Winkler, A., Thole, T., Timme, N., Kasack, K., Fuchs, S., Klironomos, F., Thiessen, N., Blanc, E., Schmelz, K., Künkele, A., Hundsdörfer, P., Rosswog, C., Theissen, J., Beule, D., Deubzer, H., Sauer, S., Toedling, J., Fischer, M., Hertwig, F., Schwarz, R.F., Eggert, A., Torrents, D., Schulte, J.H. and Henssen, A.G.
Nature Genetics 52 (1): 29-34. January 2020

Regional expression profiles of risk genes for depression are associated with brain activation patterns in emotion and reward tasks.
Komorowski, A., Vidal, R., Singh, A., Murgaš, M., Pena-Centeno, T., Gryglewski, G., Kasper, S., Wiltfang, J., Lanzenberger, R. and Goya-Maldonado, R.
bioRxiv : 2020.06.27.175257. 27 June 2020

Powerful rare variant association testing in a copula-based joint analysis of multiple phenotypes.
Konigorski, S., Yilmaz, Y.E., Janke, J., Bergmann, M.M., Boeing, H. and Pischon, T.
Genetic Epidemiology 44 (1): 26-40. January 2020

A systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics.
Konrath, F., Mittermeier, A., Cristiano, E., Wolf, J. and Loewer, A.
PLoS Computational Biology 16 (6): e1007901. 26 June 2020

Deep learning for genomics using Janggu.
Kopp, W., Monti, R., Tamburrini, A., Ohler, U. and Akalin, A.
Nature Communications 11 (1): 3488. 13 July 2020

Human cerebrospinal fluid monoclonal LGI1 autoantibodies increase neuronal excitability.
Kornau, H.C., Kreye, J., Stumpf, A., Fukata, Y., Parthier, D., Sammons, R.P., Imbrosci, B., Kurpjuweit, S., Kowski, A.B., Fukata, M., Prüss, H. and Schmitz, D.
Annals of Neurology 87 (3): 405-418. March 2020

Z-score mapping for standardized analysis and reporting of cardiovascular magnetic resonance modified Look-Locker inversion recovery (MOLLI) T1 data: normal behavior and validation in patients with amyloidosis.
Kranzusch, R., Aus dem Siepen, F., Wiesemann, S., Zange, L., Jeuthe, S., Ferreira da Silva, T., Kuehne, T., Pieske, B., Tillmanns, C., Friedrich, M.G., Schulz-Menger, J. and Messroghli, D.R.
Journal of Cardiovascular Magnetic Resonance 22 (1): 6. 20 January 2020

The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled.
Kratzer, M.C., Becker, S.F.S., Grund, A., Merks, A., Harnoš, J., Bryja, V., Giehl, K., Kashef, J. and Borchers, A.
Development 147 (10): dev186338. 22 May 2020

Renin-Angiotensin-System (RAS) und COVID-19 – Zur Verordnung von RAS-Blockern [Renin-angiotensin-system (RAS) and COVID-19 – on the prescription of RAS blockers].
Kreutz, R., Abd El-Hady Algharably, E., Ganten, D. and Messerli, F.
Deutsche Medizinische Wochenschrift 145 (10): 682-686. May 2020

A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
Kreye, J., Reincke, S.M., Kornau, H.C., Sanchez-Sendin, E., Corman, V.M., Liu, H., Yuan, M., Wu, N.C., Zhu, X., Lee, C.C.D., Trimpert, J., Hoeltje, M., Dietert, K., Stoeffler, L., von Wardenburg, N., van Hoof, S., Homeyer, M.A., Hoffmann, J., Abdelgawad, A., Gruber, A.D., Bertzbach, L.D., Vladimirova, D., Li, L.Y., Barthel, P.C., Skriner, K., Hocke, A.C., Hippenstiel, S., Witzenrath, M., Suttorp, N., Kurth, F., Franke, C., Endres, M., Schmitz, D., Jeworowski, L.M., Richter, A., Schmidt, M.L., Schwarz, T., Mueller, M.A., Drosten, C., Wendisch, D., Sander, L.E., Osterrieder, N., Wilson, I.A. and Pruess, H.
bioRxiv : 2020.08.15.252320. 16 August 2020

A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model.
Kreye, J., Reincke, S.M., Kornau, H.C., Sánchez-Sendin, E., Corman, V.M., Liu, H., Yuan, M., Wu, N.C., Zhu, X., Lee, C.C.D., Trimpert, J., Höltje, M., Dietert, K., Stöffler, L., von Wardenburg, N., van Hoof, S., Homeyer, M.A., Hoffmann, J., Abdelgawad, A., Gruber, A.D., Bertzbach, L.D., Vladimirova, D., Li, L.Y., Barthel, P.C., Skriner, K., Hocke, A.C., Hippenstiel, S., Witzenrath, M., Suttorp, N., Kurth, F., Franke, C., Endres, M., Schmitz, D., Jeworowski, L.M., Richter, A., Schmidt, M.L., Schwarz, T., Müller, M.A., Drosten, C., Wendisch, D., Sander, L.E., Osterrieder, N., Wilson, I.A. and Prüss, H.
Cell 183 (4): 1058-1069. 12 November 2020

Laying out the evidence for the persistence of neurogenesis in the adult human hippocampus.
Kronenberg, G. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 270 (4): 497-498. June 2020

Phase I dose escalation study of BI 836826 (CD37 antibody) in patients with relapsed or refractory B-cell non-Hodgkin lymphoma.
Kroschinsky, F., Middeke, J.M., Janz, M., Lenz, G., Witzens-Harig, M., Bouabdallah, R., La Rosée, P., Viardot, A., Salles, G., Kim, S.J., Kim, T.M., Ottmann, O., Chromik, J., Quinson, A.M., von Wangenheim, U., Burkard, U., Berk, A. and Schmitz, N.
Investigational New Drugs 38 (5): 1472-1482. October 2020

Proteogenomic landscape of breast cancer tumorigenesis and targeted therapy.
Krug, K., Jaehnig, E.J., Satpathy, S., Blumenberg, L., Karpova, A., Anurag, M., Miles, G., Mertins, P., Geffen, Y., Tang, L.C., Heiman, D.I., Cao, S., Maruvka, Y.E., Lei, J.T., Huang, C., Kothadia, R.B., Colaprico, A., Birger, C., Wang, J., Dou, Y., Wen, B., Shi, Z., Liao, Y., Wiznerowicz, M., Wyczalkowski, M.A., Chen, X.S., Kennedy, J.J., Paulovich, A.G., Thiagarajan, M., Kinsinger, C.R., Hiltke, T., Boja, E.S., Mesri, M., Robles, A.I., Rodriguez, H., Westbrook, T.F., Ding, L., Getz, G., Clauser, K.R., Fenyö, D., Ruggles, K.V., Zhang, B., Mani, D.R, Carr, S.A., Ellis, M.J. and Gillette, M.A.
Cell 183 (5): 1436-1456. 25 November 2020

Artificial-intelligence-driven scanning probe microscopy.
Krull, A., Hirsch, P., Rother, C., Schiffrin, A. and Krull, C.
Communications Physics 3 (1): 54. 19 March 2020

Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes.
Kräker, K., Herse, F., Golic, M., Reichhart, N., Crespo-Garcia, S., Straß, O., Grune, J., Kintscher, U., Ebrahim, M., Bader, M., Alenina, N., Heuser, A., Luft, F.C., Müller, D.N., Dechend, R. and Haase, N.
Scientific Reports 10 (1): 14061. 20 August 2020

Statins reverse postpartum cardiovascular dysfunction in a rat model of preeclampsia.
Kräker, K., O'Driscoll, J.M., Schütte, T., Herse, F., Patey, O., Golic, M., Geisberger, S., Verlohren, S., Birukov, A., Heuser, A., Mueller, D.N., Thilaganathan, B., Dechend, R. and Haase, N.
Hypertension 75 (1): 202-210. January 2020

Speckle tracking echocardiography: new ways of translational approaches in preeclampsia to detect cardiovascular dysfunction.
Kräker, K., Schütte, T., O'Driscoll, J., Birukov, A., Patey, O., Herse, F., Mueller, D.N., Thilaganathan, B., Haase, N. and Dechend, R.
International Journal of Molecular Sciences 21 (3): 1162. 10 February 2020

Cell type-specific transcriptomics of esophageal adenocarcinoma as a scalable alternative for single cell transcriptomics.
Krämer, M., Plum, P.S., Velazquez Camacho, O., Folz-Donahue, K., Thelen, M., Garcia-Marquez, I., Wölwer, C., Büsker, S., Wittig, J., Franitza, M., Altmüller, J., Löser, H., Schlößer, H., Büttner, R., Schröder, W., Bruns, C.J., Alakus, H., Quaas, A., Chon, S.H. and Hillmer, A.M.
Molecular Oncology 14 (6): 1170-1184. June 2020