A
Synthesis of multiarm star copolymers based on polyglycerol cores with polylactide arms and their application as nanocarriers.
Adeli, M., Namazi, H., Du, F., Hönzke, S., Hedtrich, S., Keilitz, J. and Haag, R.
RSC Advances 5
(20): 14958-14966.
2015
Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.
Agirre, X., Castellano, G., Pascual, M., Heath, S., Kulis, M., Segura, V., Bergmann, A., Esteve, A., Merkel, A., Raineri, E., Agueda, L., Blanc, J., Richardson, D., Clarke, L., Datta, A., Russiñol, N., Queirós, A.C., Beekman, R., Rodríguez-Madoz, J.R., San José-Enériz, E., Fang, F., Gutiérrez, N.C., García-Verdugo, J.M., Robson, M.I., Schirmer, E.C., Guruceaga, E., Martens, J.H.A., Gut, M., Calasanz, M.J., Flicek, P., Siebert, R., Campo, E., Miguel, J.F.S., Melnick, A., Stunnenberg, H.G., Gut, I.G., Prosper, F. and Martín-Subero, J.I.
Genome Research 25
(4): 478-487.
April 2015
Behandlung der Depression bei koronarer Herzerkrankung [Treatment of depression in coronary heart disease].
Agorastos, A., Lederbogen, F. and Otte, C.
Nervenarzt 86
(3): 375-387.
March 2015
Regulation of sarcoplasmic reticulum Ca(2+) ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2.
Ahmad, F., Shen, W., Vandeput, F., Szabo-Fresnais, N., Krall, J., Degerman, E., Goetz, F., Klussmann, E., Movsesian, M. and Manganiello, V.
Journal of Biological Chemistry 290
(11): 6763-6776.
13 March 2015
A common building block for the syntheses of amorfrutin and cajaninstilbene acid libraries toward efficient binding with peroxisome proliferator-activated receptors.
Aidhen, I.S., Mukkamala, R., Weidner, C. and Sauer, S.
Organic Letters 17
(2): 194-197.
16 January 2015
genomation: a toolkit to summarize, annotate and visualize genomic intervals.
Akalin, A., Franke, V., Vlahoviček, K., Mason, C.E. and Schübeler, D.
Bioinformatics 31
(7): 1127-1129.
1 April 2015
Gab1 and Mapk signaling are essential in the hair cycle and hair follicle stem cell quiescence.
Akilli Öztürk, Ö., Pakula, H., Chmielowiec, J., Qi, J., Stein, S., Lan, L., Sasaki, Y., Rajewsky, K. and Birchmeier, W.
Cell Reports 13
(3): 561-572.
20 October 2015
The GYF domain protein CD2BP2 is critical for embryogenesis and podocyte function.
Albert, G.I., Schell, C., Kirschner, K.M., Schäfer, S., Naumann, R., Müller, A., Kretz, O., Kuropka, B., Girbig, M., Hübner, N., Krause, E., Scholz, H., Huber, T.B., Knobeloch, K.P. and Freund, C.
Journal of Molecular Cell Biology 7
(5): 402-414.
October 2015
Retinal pathology in idiopathic moyamoya angiopathy detected by optical coherence tomography.
Albrecht, P., Blasberg, C., Lukas, S., Ringelstein, M., Müller, A.K., Harmel, J., Kadas, E.M., Finis, D., Guthoff, R., Aktas, O., Hartung, H.P., Paul, F., Brandt, A.U., Berlit, P., Methner, A. and Kraemer, M.
Neurology 85
(6): 521-527.
11 August 2015
The association of coffee intake with liver cancer risk is mediated by biomarkers of inflammation and hepatocellular injury: data from the European Prospective Investigation into Cancer and Nutrition.
Aleksandrova, K., Bamia, C., Drogan, D., Lagiou, P., Trichopoulou, A., Jenab, M., Fedirko, V., Romieu, I., Bueno-de-Mesquita, H.B., Pischon, T., Tsilidis, K., Overvad, K., Tjønneland, A., Bouton-Ruault, M.C., Dossus, L., Racine, A., Kaaks, R., Kuehn, T., Tsironis, C., Papatesta, E.M., Saitakis, G., Palli, D., Panico, S., Grioni, S., Tumino, R., Vineis, P., Peeters, P.H., Weiderpass, E., Lukic, M., Braaten, T., Quirós, J.R., Luján-Barroso, L., Sánchez, M.J., Chilarque, M.D., Ardanas, E., Dorronsoro, M., Nilsson, L.M., Sund, M., Wallström, P., Ohlsson, B., Bradbury, K.E., Khaw, K.T., Wareham, N., Stepien, M., Duarte-Salles, T., Assi, N., Murphy, N., Gunter, M.J., Riboli, E., Boeing, H. and Trichopoulos, D.
American Journal of Clinical Nutrition 102
(6): 1498-1508.
December 2015
A prospective study of the immune system activation biomarker neopterin and colorectal cancer risk.
Aleksandrova, K., Chuang, S.C., Boeing, H., Zuo, H., Tell, G.S., Pischon, T., Jenab, M., Bueno-de-Mesquita, B., Vollset, S.E., Midttun, Ø., Ueland, P.M., Fedirko, V., Johansson, M., Weiderpass, E., Severi, G., Racine, A., Boutron-Ruault, M.C., Kaaks, R., Kühn, T., Tjønneland, A., Overvad, K., Quirós, J.R., Jakszyn, P., Sánchez, M.J., Dorronsoro, M., Chirlaque, M.D., Ardanaz, E., Khaw, K.T., Wareham, N.J., Travis, R.C., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Palli, D., Sieri, S., Tumino, R., Panico, S., May, A.M., Palmqvist, R., Ljuslinder, I., Kong, S.Y.J., Freisling, H., Gunter, M.J., Lu, Y., Cross, A.J., Riboli, E. and Vineis, P.
Journal of the National Cancer Institute 107
(4): djv010.
April 2015
The role of serotonin in adult hippocampal neurogenesis.
Alenina, N. and Klempin, F.
Behavioural Brain Research 277
: 49-57.
15 January 2015
Angiotensin-(1-7) and Mas: a brief history.
Alenina, N. and dos Santos, R.A.
In:
The Protective Arm of the Renin Angiotensin System (RAS).
Elsevier, Amsterdam, NL, 155-159.
ISBN 9780128013649
2015
Multiple non-coding exons and alternative splicing in the mouse Mas protooncogene.
Alenina, N., Böhme, I., Bader, M. and Walther, T.
Gene 568
(2): 155-164.
1 September 2015
Increased aortic intimal proliferation due to MasR deletion in vitro.
Alsaadon, H., Kruzliak, P., Smardencas, A., Hayes, A., Bader, M., Angus, P., Herath, C. and Zulli, A.
International Journal of Experimental Pathology 96
(3): 183-187.
June 2015
High school diet and risk of Crohn's disease and ulcerative colitis.
Ananthakrishnan, A.N., Khalili, H., Song, M., Higuchi, L.M., Richter, J.M., Nimptsch, K., Wu, K. and Chan, A.T.
Inflammatory Bowel Diseases 21
(10): 2311–2319.
October 2015
Diagnosis of preeclampsia with soluble Fms-like tyrosine kinase 1/placental growth factor ratio: an inter-assay comparison.
Andersen, L.B., Frederiksen-Møller, B., Work Havelund, K., Dechend, R., Jørgensen, J.S., Jensen, B.L., Nielsen, J., Lykkedegn, S., Barington, T. and Christesen, H.T.
Journal of the American Society of Hypertension 9
(2): 86-96.
February 2015
Vitamin D depletion aggravates hypertension and target-organ damage.
Andersen, L.B., Przybyl, L., Haase, N., von Versen-Höynck, F., Qadri, F., Jørgensen, J.S., Sorensen, G.L., Fruekilde, P., Poglitsch, M., Szijártó, I., Gollasch, M., Peters, J., Muller, D.N., Christesen, H.T. and Dechend, R.
Journal of the American Heart Association 4
(2): e001417.
February 2015
The effect of (-)-Epigallo-catechin-(3)-gallate on amyloidogenic proteins suggests a common mechanism.
Andrich, K. and Bieschke, J.
Advances in Experimental Medicine and Biology 863
: 139-161.
2015
Biomarkers of postoperative delirium and cognitive dysfunction.
Androsova, G., Krause, R., Winterer, G. and Schneider, R.
Frontiers in Aging Neuroscience 7
: 112.
9 June 2015
Floral induction in Arabidopsis by FLOWERING LOCUS T requires direct repression of BLADE-ON-PETIOLE genes by the homeodomain protein PENNYWISE.
Andrés, F., Romera-Branchat, M., Martínez-Gallegos, R., Patel, V., Schneeberger, K., Jang, S., Altmüller, J., Nürnberg, P. and Coupland, G.
Plant Physiology 169
(3): 2187-2199.
November 2015
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.
Arner, E., Daub, C.O., Vitting-Seerup, K., Andersson, R., Lilje, B., Drabløs, F., Lennartsson, A., Rönnerblad, M., Hrydziuszko, O., Vitezic, M., Freeman, T.C., Alhendi, A., Arner, P., Axton, R., Baillie, J.K., Beckhouse, A., Bodega, B., Briggs, J., Brombacher, F., Davis, M., Detmar, M., Ehrlund, A., Endoh, M., Eslami, A., Fagiolini, M., Fairbairn, L., Faulkner, G.J., Ferrai, C., Fisher, M.E., Forrester, L., Goldowitz, D., Guler, R., Ha, T., Hara, M., Herlyn, M., Ikawa, T., Kai, C., Kawamoto, H., Khachigian, L., Klinken, P.S., Kojima, S., Koseki, H., Klein, S., Mejhert, N., Miyaguchi, K., Mizuno, Y., Morimoto, M., Morris, K.J., Mummery, C., Nakachi, Y., Ogishima, S., Okada-Hatakeyama, M., Okazaki, Y., Orlando, V., Ovchinnikov, D., Passier, R., Patrikakis, M., Pombo, A., Qin, X.Y., Roy, S., Sato, H., Savvi, S., Saxena, A., Schwegmann, A., Sugiyama, D., Swoboda, R., Tanaka, H., Tomoiu, A., Winteringham, L.N., Wolvetang, E., Yanagi-Mizuochi, C., Yoneda, M., Zabierowski, S., Zhang, P., Abugessaisa, I., Bertin, N., Diehl, A.D., Fukuda, S., Furuno, M., Harshbarger, J., Hasegawa, A., Hori, F., Ishikawa-Kato, S., Ishizu, Y., Itoh, M., Kawashima, T., Kojima, M., Kondo, N., Lizio, M., Meehan, T.F., Mungall, C.J., Murata, M., Nishiyori-Sueki, H., Sahin, S., Sato-Nagao, S., Severin, J., de Hoon, M.J., Kawai, J., Kasukawa, T., Lassmann, T., Suzuki, H., Kawaji, H., Summers, K.M., Wells, C., Hume, D.A., Forrest, A.R.R., Sandelin, A., Carninci, P. and Hayashizaki, Y.
Science 347
(6225): 1010-1014.
27 February 2015
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Aspalter, I.M., Gordon, E., Dubrac, A., Ragab, A., Narloch, J., Vizán, P., Geudens, I., Collins, R.T., Franco, C.A., Abrahams, C.L., Thurston, G., Fruttiger, M., Rosewell, I., Eichmann, A. and Gerhardt, H.
Nature Communications 6
: 7264.
17 June 2015
A grainyhead-like 2/Ovo-like 2 pathway regulates renal epithelial barrier function and lumen expansion.
Aue, A., Hinze, C., Walentin, K., Ruffert, J., Yurtdas, Y., Werth, M., Chen, W., Rabien, A., Kilic, E., Schulzke, J.D., Schumann, M. and Schmidt-Ott, K.M.
Journal of the American Society of Nephrology 26
(11): 2704-2715.
November 2015
Single molecule fluorescence microscopy on planar supported bilayers.
Axmann, M., Schütz, G.J. and Huppa, J.B.
Journal of Visualized Experiments
(105): e53158.
31 October 2015
Measuring TCR-pMHC binding in situ using a FRET-based microscopy assay.
Axmann, M., Schütz, G.J. and Huppa, J.B.
Journal of Visualized Experiments
(105): e53157.
30 October 2015
B
A rapid embryonic stem cell-based mouse model for B-cell lymphomas driven by Epstein-Barr virus protein LMP1.
Ba, Z., Meng, F.L., Gostissa, M., Huang, P.Y., Ke, Q., Wang, Z., Dao, M.N., Fujiwara, Y., Rajewsky, K., Zhang, B. and Alt, F.W.
Cancer Immunology Research 3
(6): 641-649.
June 2015
Suppression of peripheral pain by blockade of voltage-gated calcium 2.2 channels in nociceptors induces RANKL and impairs recovery from inflammatory arthritis in a mouse model.
Baddack, U., Frahm, S., Antolin-Fontes, B., Grobe, J., Lipp, M., Mueller, G. and Ibanez-Tallon, I.
Arthritis & Rheumatology 67
(6): 1657-1667.
June 2015
The Green Gut: chlorophyll degradation in the gut of Spodoptera littoralis.
Badgaa, A., Büchler, R., Wielsch, N., Walde, M., Heintzmann, R., Pauchet, Y., Svatos, A., Ploss, K. and Boland, W.
Journal of Chemical Ecology 41
(11): 965-974.
November 2015
Whole-body MR imaging in the German National Cohort: rationale, design, and technical background.
Bamberg, F., Kauczor, H.U., Weckbach, S., Schlett, C.L., Forsting, M., Ladd, S.C., Greiser, K.H., Weber, M.A., Schulz-Menger, J., Niendorf, T., Pischon, T., Caspers, S., Amunts, K., Berger, K., Bülow, R., Hosten, N., Hegenscheid, K., Kröncke, T., Linseisen, J., Günther, M., Hirsch, J.G., Köhn, A., Hendel, T., Wichmann, H.E., Schmidt, B., Jöckel, K.H., Hoffmann, W., Kaaks, R., Reiser, M.F. and Völzke, H.
Radiology 277
(1): 206-220.
October 2015
Coffee, tea and decaffeinated coffee in relation to hepatocellular carcinoma in a European population: multicentre, prospective cohort study.
Bamia, C., Lagiou, P., Jenab, M., Trichopoulou, A., Fedirko, V., Aleksandrova, K., Pischon, T., Overvad, K., Olsen, A., Tjønneland, A., Boutron-Ruault, M.C., Fagherazzi, G., Racine, A., Kuhn, T., Boeing, H., Floegel, A., Benetou, V., Palli, D., Grioni, S., Panico, S, Tumino, R., Vineis, P., Bueno-de-Mesquita, H.B., Dik, V.K., Bhoo-Pathy, N., Uiterwaal, C.S., Weiderpass, E., Lund, E., Quirós, J.R., Zamora-Ros, R., Molina-Montes, E., Chirlaque, M.D., Ardanaz, E., Dorronsoro, M., Lindkvist, B., Wallström, P., Nilsson, L.M., Sund, M., Khaw, K.T., Wareham, N., Bradbury, K.E., Travis, R.C., Ferrari, P., Duarte-Salles, T., Stepien, M., Gunter, M., Murphy, N., Riboli, E. and Trichopoulos, D.
International Journal of Cancer 136
(8): 1899-1908.
15 April 2015
Super natural II -a database of natural products.
Banerjee, P., Erehman, J., Gohlke, B.O., Wilhelm, T., Preissner, R. and Dunkel, M.
Nucleic Acids Research 43
(Database issue): D935-D939.
28 January 2015
Aβ42-oligomer Interacting Peptide (AIP) neutralizes toxic amyloid-β42 species and protects synaptic structure and function.
Barucker, C., Bittner, H.J., Chang, P.K.Y., Cameron, S., Hancock, M.A., Liebsch, F., Hossain, S., Harmeier, A., Shaw, H., Charron, F.M., Gensler, M., Dembny, P., Zhuang, W., Schmitz, D., Rabe, J.P., Rao, Y., Lurz, R., Hildebrand, P.W., McKinney, R.A. and Multhaup, G.
Scientific Reports 5
: 15410.
29 October 2015
Alzheimer amyloid Peptide aβ42 regulates gene expression of transcription and growth factors.
Barucker, C., Sommer, A., Beckmann, G., Eravci, M., Harmeier, A., Schipke, C.G., Brockschnieder, D., Dyrks, T., Althoff, V., Fraser, P.E., Hazrati, L.N., St George-Hyslop, P., Breitner, J.C.S., Peters, O. and Multhaup, G.
Journal of Alzheimer's Disease 44
(2): 613-624.
1 January 2015
Ancient gene duplications have shaped developmental stage-specific expression in Pristionchus pacificus.
Baskaran, P., Roedelsperger, C., Prabh, N., Serobyan, V., Markov, G.V., Hirsekorn, A. and Dieterich, C.
BMC Evolutionary Biology 15
(1): 185.
15 September 2015
Pathogenicity of POFUT1 in Dowling-Degos disease: additional mutations and clinical overlap with reticulate acropigmentation of kitamura.
Basmanav, F.B., Fritz, G., Lestringant, G.G., Pachat, D., Hoffjan, S., Fischer, J., Wehner, M., Wolf, S., Thiele, H., Altmüller, J., Pulimood, S.A., Rütten, A., Kruse, R., Hanneken, S., Frank, J., Danda, S., Bygum, A. and Betz, R.C.
Journal of Investigative Dermatology 135
(2): 615-618.
February 2015
Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation.
Baubec, T., Colombo, D.F., Wirbelauer, C., Schmidt, J., Burger, L., Krebs, A.R., Akalin, A. and Schübeler, D.
Nature 520
(7546): 243-247.
9 April 2015
Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms.
Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A.D., Kabesch, M., Lee, Y.A.E., Lieb, W., Marenholz, I., McLean, W.H.I., Morris, D.W., Mrowietz, U., Nair, R., Nöthen, M.M., Novak, N., O'Regan, G.M., Schreiber, S., Smith, C., Strauch, K., Stuart, P.E., Trembath, R., Tsoi, L.C., Weichenthal, M., Barker, J., Elder, J.T., Weidinger, S., Cordell, H.J. and Brown, S.J.
American Journal of Human Genetics 96
(1): 104-120.
8 January 2015
Cancer evolution: mathematical models and computational inference.
Beerenwinkel, N., Schwarz, R.F., Gerstung, M. and Markowetz, F.
Systematic Biology 64
(1): e1-e25.
January 2015
Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial.
Behringer, K., Goergen, H., Hitz, F., Zijlstra, J.M., Greil, R., Markova, J., Sasse, S., Fuchs, M., Topp, M.S., Soekler, M., Mathas, S., Meissner, J., Wilhelm, M., Koch, P., Lindemann, H.W., Schalk, E., Semrau, R., Kriz, J., Vieler, T., Bentz, M., Lange, E., Mahlberg, R., Hassler, A., Vogelhuber, M., Hahn, D., Mezger, J., Krause, S.W., Skoetz, N., Böll, B., von Tresckow, B., Diehl, V., Hallek, M., Borchmann, P., Stein, H., Eich, H. and Engert, A.
Lancet 385
(9976): 1418-1427.
11 April 2015
Brain serotonin deficiency leads to social communication deficits in mice.
Beis, D., Holzwarth, K., Flinders, M., Mosienko, V., Bader, M., Wöhr, M. and Alenina, N.
Biology Letters 11
(3): 20150057.
March 2015
Role of Foxl2 in uterine maturation and function.
Bellessort, B., Bachelot, A., Heude, É., Alfama, G., Fontaine, A., Le Cardinal, M., Treier, M. and Levi, G.
Human Molecular Genetics 24
(11): 3092-3103.
1 June 2015
Mathematical modelling suggests differential impact of β-TrCP paralogues on Wnt/β-catenin signalling dynamics.
Benary, U., Kofahl, B., Hecht, A. and Wolf, J.
FEBS Journal 282
(6): 1080-1096.
March 2015
Corticotropin-releasing hormone receptor type 1 (CRHR1) clustering with MAGUKs is mediated via its C-terminal PDZ binding motif.
Bender, J., Engeholm, M., Ederer, M.S., Breu, J., Møller, T.C., Michalakis, S., Rasko, T., Wanker, E.E., Biel, M., Martinez, K.L., Wurst, W. and Deussing, J.M.
PLoS ONE 10
(9): e0136768.
9 September 2015
Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography.
Bennett, J.L., de Seze, J., Lana-Peixoto, M., Palace, J., Waldman, A., Schippling, S., Tenembaum, S., Banwell, B., Greenberg, B., Levy, M., Fujihara, K., Chan, K.H., Kim, H.J., Asgari, N., Sato, D.K., Saiz, A., Wuerfel, J., Zimmermann, H., Green, A., Villoslada, P. and Paul, F.
Multiple Sclerosis Journal 21
(6): 678-688.
May 2015
Stimulating translational research: several European life science institutions put their heads together.
Bentires-Alj, M., Rajan, A., van Harten, W., van Luenen, H.G.A.M., Kubicek, S., Andersen, J.B., Saarela, J., Cook, S.J., van Minnebruggen, G., Roman-Roman, S., Maurer, C., Erler, J.T. and Bertero, M.G.
Trends in Molecular Medicine 21
(9): 525-527.
September 2015
Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia.
Berenstein, R., Blau, I.W., Suckert, N., Baldus, C., Pezzutto, A., Dörken, B. and Blau, O.
Journal of Experimental & Clinical Cancer Research 34
(1): 55.
22 May 2015
Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region.
Berenstein, R., Blau, O., Nogai, A., Waechter, M., Slonova, E., Schmidt-Hieber, M., Kunitz, A., Pezzutto, A., Doerken, B. and Blau, I.W.
BMC Cancer 15
(1): 68.
18 February 2015
Comparison of diffusion tensor imaging by cardiovascular magnetic resonance and gadolinium enhanced 3D image intensity approaches to investigation of structural anisotropy in explanted rat hearts.
Bernus, O., Radjenovic, A., Trew, M.L., LeGrice, I.J., Sands, G.B., Magee, D.R., Smaill, B.H. and Gilbert, S.H.
Journal of Cardiovascular Magnetic Resonance 17
(1): 31.
29 April 2015
A t(3;9)(q25.1;q34.3) translocation leading to OLFM1 fusion transcripts in Gilles de la Tourette syndrome, OCD and ADHD.
Bertelsen, B., Melchior, L., Jensen, L.R., Groth, C., Nazaryan, L., Debes, N.M., Skov, L., Xie, G., Sun, W., Brondum-Nielsen, K., Kuss, A.W., Chen, W. and Tuemer, Z.
Psychiatry Research 225
(3): 268-275.
28 February 2015
Sodium chloride, SGK1, and Th17 activation.
Binger, K.J., Linker, R.A., Muller, D.N. and Kleinewietfeld, M.
Pfluegers Archiv European Journal of Physiology 467
(3): 543-550.
March 2015
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.
Binger, K.J., Gebhardt, M., Heinig, M., Rintisch, C., Schroeder, A., Neuhofer, W., Hilgers, K., Manzel, A., Schwartz, C., Kleinewietfeld, M., Voelkl, J., Schatz, V., Linker, R.A., Lang, F., Voehringer, D., Wright, M.D., Hubner, N., Dechend, R., Jantsch, J., Titze, J. and Müller, D.N.
Journal of Clinical Investigation 125
(11): 4223-4238.
2 November 2015
The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling.
Birdsey, G.M., Shah, A.V., Dufton, N., Reynolds, L.E., Osuna Almagro, L., Yang, Y., Aspalter, I.M., Khan, S.T., Mason, J.C., Dejana, E., Göttgens, B., Hodivala-Dilke, K., Gerhardt, H., Adams, R.H. and Randi, A.M.
Developmental Cell 32
(1): 82-96.
12 January 2015
Comprehensive protein interactome analysis of a key RNA helicase: detection of novel stress granule proteins.
Bish, R., Cuevas-Polo, N., Cheng, Z., Hambardzumyan, D., Munschauer, M., Landthaler, M. and Vogel, C.
Biomolecules 5
(3): 1441-1466.
15 July 2015
Ly6C(high) monocytes control cerebral toxoplasmosis.
Biswas, A., Bruder, D., Wolf, S.A., Jeron, A., Mack, M., Heimesaat, M.M. and Dunay, I.R.
Journal of Immunology 194
(7): 3223-3235.
1 April 2015
Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.
Blackburn, J., Kawasaki, K., Porntaveetus, T., Kawasaki, M., Otsuka-Tanaka, Y., Miake, Y., Ota, M.S., Watanabe, M., Hishinuma, M., Nomoto, T., Oommen, S., Ghafoor, S., Harada, F., Nozawa-Inoue, K., Maeda, T., Peterkova, R., Lesot, H., Inoue, J., Akiyama, T., Schmidt-Ullrich, R., Liu, B., Hu, Y., Page, A., Ramirez, A., Sharpe, P.T. and Ohazama, A.
Journal of Dental Research 94
(1): 121-128.
January 2015
Effect of angiotensin(1-7) on heart function in an experimental rat model of obesity.
Blanke, K., Schlegel, F., Raasch, W., Bader, M., Dähnert, I., Dhein, S. and Salameh, A.
Frontiers in Physiology 6
: 392.
21 December 2015
Targeting cancer-specific mutations by T cell receptor gene therapy.
Blankenstein, T., Leisegang, M., Uckert, W. and Schreiber, H.
Current Opinion in Immunology 33
: 112-119.
April 2015
microRNAs regulate cell-to-cell variability of endogenous target gene expression in developing mouse thymocytes.
Blevins, R., Bruno, L., Carroll, T., Elliott, J., Marcais, A., Loh, C., Hertweck, A., Krek, A., Rajewsky, N., Chen, C.Z., Fisher, A.G. and Merkenschlager, M.
PLoS Genetics 11
(2): e1005020.
25 February 2015
DoRiNA 2.0-upgrading the doRiNA database of RNA interactions in post-transcriptional regulation.
Blin, K., Dieterich, C., Wurmus, R., Rajewsky, N., Landthaler, M. and Akalin, A.
Nucleic Acids Research 43
(Database issue): D160-D167.
28 January 2015
A potential pathophysiological role for galectins and the renin-angiotensin system in preeclampsia.
Blois, S.M., Dechend, R., Barrientos, G. and Staff, A.C.
Cellular and Molecular Life Sciences 72
(1): 39-50.
January 2015
Chemerin and prediction of diabetes mellitus type 2.
Bobbert, T., Schwarz, F., Fischer-Rosinsky, A., Maurer, L., Moehlig, M., Pfeiffer, A.F.H., Mai, K. and Spranger, J.
Clinical Endocrinology 82
(6): 838-843.
June 2015
The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey.
Bocchetta, M., Galluzzi, S., Kehoe, P.G., Aguera, E., Bernabei, R., Bullock, R., Ceccaldi, M., Dartigues, J.F., de Mendonca, A., Didic, M., Eriksdotter, M., Felician, O., Froelich, L., Gertz, H.J., Hallikainen, M., Hasselbalch, S.G., Hausner, L., Heuser, I., Jessen, F., Jones, R.W., Kurz, A., Lawlor, B., Lleo, A., Martinez-Lage, P., Mecocci, P., Mehrabian, S., Monsch, A., Nobili, F., Nordberg, A., Rikkert, M.O., Orgogozo, J.M., Pasquier, F., Peters, O., Salmon, E., Sanchez-Castellano, C., Santana, I., Sarazin, M., Traykov, L., Tsolaki, M., Visser, P.J., Wallin, A.K., Wilcock, G., Wilkinson, D., Wolf, H., Yener, G., Zekry, D. and Frisoni, G.B.
Alzheimer's & Dementia 11
(2): 195-206.
February 2015
Identification and characterization of hypoxia-regulated endothelial circular RNA.
Boeckel, J.N., Jae, N., Heumueller, A.W., Chen, W., Boon, R.A., Stellos, K., Zeiher, A.M., John, D., Uchida, S. and Dimmeler, S.
Circulation Research 117
(10): 884-890.
23 October 2015
Quest for Orthologs entails quest for Tree of Life: in search of the gene stream.
Boeckmann, B., Marcet-Houben, M., Rees, J.A., Forslund, K., Huerta-Cepas, J., Muffato, M., Yilmaz, P., Xenarios, I., Bork, P., Lewis, S.E. and Gabaldon, T.
Genome Biology and Evolution 7
(7): 1988-1999.
1 July 2015
Visceral leishmaniasis diagnosis and reporting delays as an obstacle to timely response actions in Nepal and India.
Boettcher, J.P., Siwakoti, Y., Milojkovic, A., Siddiqui, N.A., Gurung, C.K., Rijal, S., Das, P., Kroeger, A. and Banjara, M.R.
BMC Infectious Diseases 15
(1): 43.
6 February 2015
Induction of Ankrd1 in dilated cardiomyopathy correlates with the heart failure progression.
Bogomolovas, J., Brohm, K., Čelutkiené, J., Balčiūnaité, G., Bironaité, D., Bukelskiené, V., Daunoravičus, D., Witt, C.C., Fielitz, J., Grabauskiené, V. and Labeit, S.
BioMed Research International 2015
: 273936.
2015
Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains.
Bolger, G.B., Dunlop, A.J., Meng, D., Day, J.P., Klussmann, E., Baillie, G.S., Adams, D.R. and Houslay, M.D.
Cellular Signalling 27
(4): 756-769.
April 2015
BRF1 mutations alter RNA polymerase III–dependent transcription and cause neurodevelopmental anomalies.
Borck, G., Hög, F., Dentici, M.L., Tan, P.L., Sowada, N., Medeira, A., Gueneau, L., Thiele, H., Kousi, M., Lepri, F., Wenzeck, L., Blumenthal, I., Radicioni, A., Schwarzenberg, T.L., Mandriani, B., Fischetto, R., Morris-Rosendahl, D.J., Altmüller, J., Reymond, A., Nürnberg, P., Merla, G., Dallapiccola, B., Katsanis, N., Cramer, P. and Kubisch, C.
Genome Research 25
(2): 155-166.
February 2015
Label-free protein-RNA interactome analysis identifies khsrp signaling downstream of the p38/Mk2 kinase complex as a critical modulator of cell cycle progression.
Boucas, J., Fritz, C., Schmitt, A., Riabinska, A., Thelen, L., Peifer, M., Leeser, U., Nuernberg, P., Altmüller, J., Gaestel, M., Dieterich, C. and Reinhardt, H.C.
PLoS ONE 10
(5): e0125745.
2015
Magnetic resonance phase alterations in multiple sclerosis patients with short and long disease duration.
Bozin, I., Ge, Y., Kuchling, J., Dusek, P., Chawla, S., Harms, L., Ruprecht, K., Niendorf, T., Paul, F., Kister, I., Sinnecker, T. and Wuerfel, J.
PLoS ONE 10
(7): e0128386.
17 July 2015
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
Brandl, C., Ortiz, O., Röttig, B., Wefers, B., Wurst, W. and Kühn, R.
FEBS Open Bio 5
: 26-35.
2015
Susceptibility of murine induced pluripotent stem cell-derived cardiomyocytes to hypoxia and nutrient deprivation.
Brodarac, A., Šarić, T., Oberwallner, B., Mahmoodzadeh, S., Neef, K., Albrecht, J., Burkert, K., Oliverio, M., Nguemo, F., Choi, Y.H., Neiss, W.F., Morano, I., Hescheler, J. and Stamm, C.
Stem Cell Research & Therapy 6
(1): 83.
23 April 2015
Assessing mitochondrial movement within neurons: manual versus automated tracking methods.
Bros, H., Hauser, A., Paul, F., Niesner, R. and Infante-Duarte, C.
Traffic 16
(8): 906-917.
August 2015
An ex vivo model for studying mitochondrial trafficking in neurons.
Bros, H., Niesner, R. and Infante-Duarte, C.
Methods in Molecular Biology 1264
: 465-472.
2015
Patterns and ecological drivers of ocean viral communities.
Brum, J.R., Ignacio-Espinoza, J.C., Roux, S., Doulcier, G., Acinas, S.G., Alberti, A., Chaffron, S., Cruaud, C., de Vargas, C., Gasol, J.M., Gorsky, G., Gregory, A.C., Guidi, L., Hingamp, P., Iudicone, D., Not, F., Ogata, H., Pesant, S., Poulos, B.T., Schwenck, S.M., Speich, S., Dimier, C., Kandels-Lewis, S., Picheral, M., Searson, S., Bork, P., Bowler, C., Sunagawa, S., Wincker, P., Karsenti, E. and Sullivan, M.B.
Science 348
(6237): 1261498.
22 May 2015
Skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia is caused by a novel mutation in B3GAT3.
Budde, B.S., Mizumoto, S., Kogawa, R., Becker, C., Altmüller, J., Thiele, H., Rueschendorf, F., Toliat, M.R., Kaleschke, G., Haemmerle, J.M., Hoehne, W., Sugahara, K., Nuernberg, P. and Kennerknecht, I.
Human Genetics 134
(7): 691-704.
July 2015
Differences in maintenance of response upon discontinuation across medication treatments in attention-deficit/hyperactivity disorder.
Buitelaar, J., Asherson, P., Soutullo, C., Colla, M., Adams, D.H., Tanaka, Y., Haynes, V.S., Escobar, R. and Upadhyaya, H.
European Neuropsychopharmacology 25
(10): 1611–1621.
October 2015
Circulating metastasis associated in colon cancer 1 transcripts in gastric cancer patient plasma as diagnostic and prognostic biomarker.
Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Stein, U.
World Journal of Gastroenterology 21
(1): 333-341.
7 January 2015
Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas.
Busch, J., Ralla, B., Jung, M., Wotschofsky, Z., Trujillo-Arribas, E., Schwabe, P., Kilic, E., Fendler, A. and Jung, K.
Journal of Experimental & Clinical Cancer Research 34
(1): 61.
14 June 2015
Arabidopsis KCBP interacts with AIR9 but stays in the cortical division zone throughout mitosis via its MyTH4-FERM domain.
Buschmann, H., Dols, J., Kopischke, S., Pena, E.J., Andrade-Navarro, M.A., Heinlein, M., Szymanski, D.B., Zachgo, S., Doonan, J.H. and Lloyd, C.W.
Journal of Cell Science 28
(11): 2033-2046.
1 June 2015
ZBTB17 (MIZ1) is important for the cardiac stress response and a novel candidate gene for cardiomyopathy and heart failure.
Buyandelger, B., Mansfield, C., Kostin, S., Choi, O., Roberts, A.M., Ware, J.S., Mazzarotto, F., Pesce, F., Buchan, R., Isaacson, R.L., Vouffo, J., Gunkel, S., Knoell, G., McSweeney, S.J., Wei, H., Perrot, A., Pfeiffer, C., Toliat, M.R., Ilieva, K., Krysztofinska, E., López-Olañeta, M.M., Gómez-Salinero, J.M., Schmidt, A., Ng, K.E., Teucher, N., Chen, J., Teichmann, M., Eilers, M., Haverkamp, W., Regitz-Zagrosek, V., Hasenfuss, G., Braun, T., Pennell, D.J., Gould, I., Barton, P.J.R., Lara-Pezzi, E., Schäfer, S., Hübner, N., Felkin, L.E., O'Regan, D.P., Petretto, E., Brand, T., Milting, H., Nürnberg, P., Schneider, M.D., Prasad, S. and Knöll, R.
Circulation Cardiovascular Genetics 8
(5): 643-652.
October 2015
Deregulation of the endogenous C/EBPβ LIP isoform predisposes to tumorigenesis.
Bégay, V., Smink, J.J., Loddenkemper, C., Zimmermann, K., Rudolph, C., Scheller, M., Steinemann, D., Leser, U., Schlegelberger, B., Stein, H. and Leutz, A.
Journal of Molecular Medicine 93
(1): 39-49.
January 2015
Serotonin attenuates feedback excitation onto O-LM interneurons.
Böhm, C., Pangalos, M., Schmitz, D. and Winterer, J.
Cerebral Cortex 25
(11): 4572-4583.
November 2015
Functional diversity of subicular principal cells during hippocampal ripples.
Böhm, C., Peng, Y., Maier, N., Winterer, J., Poulet, J.F.A., Geiger, J.R.P. and Schmitz, D.
Journal of Neuroscience 35
(40): 13608-13618.
7 October 2015
C
The proepicardium keeps a potential for glomerular marker expression which supports its evolutionary origin from the pronephros.
Cano, E., Carmona, R., Velecela, V., Martinez-Estrada, O. and Munoz-Chapuli, R.
Evolution & Development 17
(4): 224-230.
July 2015
Assessment of renal hemodynamics and oxygenation by simultaneous magnetic resonance imaging (MRI) and quantitative invasive physiological measurements.
Cantow, K., Arakelyan, K., Seeliger, E., Niendorf, T. and Pohlmann, A.
Methods in Molecular Biology 1397
: 129-154.
17 December 2015
Prediagnostic plasma IGFBP-1, IGF-1 and risk of prostate cancer.
Cao, Y., Nimptsch, K., Shui, I.M., Platz, E.A., Wu, K., Pollak, M.N., Kenfield, S.A., Stampfer, M.J. and Giovannucci, E.L.
International Journal of Cancer 136
(10): 2418-2426.
15 May 2015
Efficient set tests for the genetic analysis of correlated traits.
Casale, F.P., Rakitsch, B., Lippert, C. and Stegle, O.
Nature Methods 12
(8): 755-758.
August 2015
Foxg1-Cre mediated Lrp2 inactivation in the developing mouse neural retina, ciliary and retinal pigment epithelia models congenital high myopia.
Cases, O., Joseph, A., Obry, A., Santin, M.D., Ben-Yacoub, S., Paques, M., Amsellem-Levera, S., Bribian, A., Simonutti, M., Augustin, S., Debeir, T., Sahel, J.A., Christ, A., de Castro, F., Lehericy, S., Cosette, P. and Kozyraki, R.
PLoS ONE 10
(6): e0129518.
24 June 2015
Identification of region-specific myocardial gene expression patterns in a chronic swine model of repaired tetralogy of fallot.
Charron, S., Roubertie, F., Benoist, D., Dubes, V., Gilbert, S.H., Constantin, M., Vieillot, D., Elbes, D., Quesson, B., Bordachar, P., Haissaguerre, M., Bernus, O., Thambo, J.B. and Rooryck, C.
PLoS ONE 10
(8): e0134146.
7 August 2015
Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature.
Chen, L., Kaßmann, M., Sendeski, M., Tsvetkov, D., Marko, L., Michalick, L., Riehle, M., Wolfgang, L.B., Wolfgang, K.M., Harteneck, C., Tepel, M., Patzak, A. and Gollasch, M.
Acta Physiologica 213
(2): 481-491.
February 2015
Identification of 2-[4-[(4-methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers.
Cheng, X., Dimou, E., Alborzinia, H., Wenke, F., Goehring, A., Reuter, S., Mah, N., Fuchs, H., Andrade-Navarro, M.A., Adjaye, J., Gul, S., Harms, C., Utikal, J., Klipp, E., Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58
(12): 4976-4983.
25 June 2015
Ethyl 2-((4-chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4.
Cheng, X., Yoshida, H., Raoofi, D., Saleh, S., Alborzinia, H., Wenke, F., Goehring, A., Reuter, S., Mah, N., Fuchs, H.R., Andrade-Navarro, M.A., Adjaye, J., Gul, S., Utikal, J., Mrowka, R. and Woelfl, S.
Journal of Medicinal Chemistry 58
(1): 5742-5750.
13 August 2015
Ectodysplasin signalling genes and phenotypic evolution in sculpins (Cottus).
Cheng, J., Sedlazek, F., Altmüller, J. and Nolte, A.W.
Proceedings of the Royal Society of London Series B-Biological Sciences 282
(1815): 20150746.
22 September 2015
Polymer models of the organization of chromosomes in the nucleus of cells.
Chiariello, A.M., Bianco, S., Piccolo, A., Annunziatella, C., Barbieri, M., Pombo, A. and Nicodemi, M.
Modern Physics Letters B 29
(9): 1530003.
10 April 2015
LRP2 acts as SHH clearance receptor to protect the retinal margin from mitogenic stimuli.
Christ, A., Christa, A., Klippert, J., Eule, J.C., Bachmann, S., Wallace, V.A., Hammes, A. and Willnow, T.E.
Developmental Cell 35
(1): 36-48.
12 October 2015
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu, V.T., Weber, T., Wefers, B., Wurst, W., Sander, S., Rajewsky, K. and Kühn, R.
Nature Biotechnology 33
(5): 543-548.
May 2015
Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
Chumduri, C., Gillissen, B., Richter, A., Richter, A., Milojkovic, A., Overkamp, T., Mueller, A., Pott, C. and Daniel, P.T.
Journal of Molecular Medicine 93
(5): 559-572.
May 2015
Autophagy is activated in systemic lupus erythematosus and required for plasmablast development.
Clarke, A.J., Ellinghaus, U., Cortini, A., Stranks, A., Simon, A.K., Botto, M. and Vyse, T.J.
Annals of the Rheumatic Diseases 74
(5): 912-20.
May 2015
Transforming growth factor type-β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular dystrophies.
Cofre, C., Acuna, M.J., Contreras, O., Morales, M.G., Riquelme, C., Bader, M., Santos, R., Cabello-Verrugio, C. and Brandan, E.
BioFactors 41
(2): 111-120.
March 2015
Redox regulation of cell contacts by tricellulin and occludin: redox-sensitive cysteine sites in tricellulin regulate both tri- and bicellular junctions in tissue barriers as shown in hypoxia and ischemia.
Cording, J., Günther, R., Vigolo, E., Tscheik, C., Winkler, L., Schlattner, I., Lorenz, D., Haseloff, R.F., Schmidt-Ott, K.M., Wolburg, H. and Blasig, I.E.
Antioxidants & Redox Signaling 23
(13): 1035-1049.
5 November 2015
An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia.
Cornelius, D.C., Amaral, L.M., Harmon, A., Wallace, K., Thomas, A.J., Campbell, N., Scott, J., Herse, F., Haase, N., Moseley, J., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 309
(8): R884-R891.
15 October 2015
Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT1-AA in response to adoptive transfer of CD4(+) T lymphocytes from RUPP rats.
Cornelius, D.C., Castillo, J., Porter, J., Amaral, L.M., Campbell, N., Paige, A., Thomas, A.J., Harmon, A., Cunningham, M.W., Wallace, K., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.D.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 309
(10): R1243-R1250.
15 November 2015
Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.
Correia, J.C., Massart, J., de Boer, J.F., Porsmyr-Palmertz, M., Martínez-Redondo, V., Agudelo, L.Z., Sinha, I., Meierhofer, D., Ribeiro, V., Björnholm, M., Sauer, S., Dahlman-Wright, K., Zierath, J.R., Groen, A.K. and Ruas, J.L.
Molecular Metabolism 4
(12): 891-902.
December 2015
Reproducible and user-controlled software environments in HPC with Guix.
Courtes, L. and Wurmus, R.
Lecture Notes in Computer Science 9523
: 579-591.
2015
Lin41/Trim71 is essential for mouse development and specifically expressed in postnatal ependymal cells of the brain.
Cuevas, E., Rybak-Wolf, A., Rohde, A.M., Nguyen, D.T.T. and Wulczyn, F.G.
Frontiers in Cell and Developmental Biology 3
: 20.
2 April 2015
Gene regulatory network evolution through augmenting topologies.
Cussat-Blanc, S., Harrington, K. and Pollack, J.
IEEE Transactions on Evolutionary Computation 19
(6): 823-837.
December 2015
Genetically-regulated neuromodulation facilitates multi-task reinforcement learning.
Cussat-Blanc, S. and Harrington, K.I.S.
In: GECCO '15: Genetic and Evolutionary Computation Conference, Jul 2015, Madrid, Spain.
July 2015
Ecological transcriptomics – a non-lethal sampling approach for endangered fire salamanders.
Czypionka, T., Krugman, T., Altmüller, J., Blaustein, L., Steinfartz, S., Templeton, A.R., Nolte, A.W. and Leder, E.
Methods in Ecology and Evolution 6
(12): 1417-1425.
December 2015
D
RNA interference for antimetastatic therapy.
Dahlmann, M. and Stein, U.
Methods in Molecular Biology 1317
: 153-165.
2015
Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients.
Dahlmann, A., Dörfelt, K., Eicher, F., Linz, P., Kopp, C., Mössinger, I., Horn, S., Büschges-Seraphin, B., Wabel, P., Hammon, M., Cavallaro, A., Eckardt, K.U., Kotanko, P., Levin, N.W., Johannes, B., Uder, M., Luft, F.C., Müller, D.N. and Titze, J.M.
Kidney International 87
(2): 434-441.
February 2015
Successful replication of GWAS hits for multiple sclerosis in 10,000 Germans using the exome array.
Dankowski, T., Buck, D., Andlauer, T.F.M., Antony, G., Bayas, A., Bechmann, L., Berthele, A., Bettecken, T., Chan, A., Franke, A., Gold, R., Graetz, C., Haas, J., Hecker, M., Herms, S., Infante-Duarte, C., Jöckel, K.H., Kieseier, B.C., Knier, B., Knop, M., Kümpfel, T., Lichtner, P., Lieb, W., Lill, C.M., Limmroth, V., Linker, R.A., Loleit, V., Meuth, S.G., Moebus, S., Müller-Myhsok, B., Nischwitz, S., Nöthen, M.M., Paul, F., Puetz, M., Ruck, T., Salmen, A., Stangel, M., Stellmann, J.P., Strauch, K., Stürner, K.H., Tackenberg, B., Then Bergh, F., Tumani, H., Waldenberger, M., Weber, F., Wiendl, H., Wildemann, B., Zettl, U.K., Ziemann, U., Zipp, F., Hemmer, B. and Ziegler, A.
Genetic Epidemiology 39
(8): 601-608.
December 2015
T cells engineered to express a T-cell receptor specific for glypican-3 recognize and kill hepatoma cells in vitro and in mice.
Dargel, C., Bassani-Sternberg, M., Hasreiter, J., Zani, F., Bockmann, J.H., Thiele, F., Bohne, F., Wisskirchen, K., Wilde, S., Sprinzl, M.F., Schendel, D.J., Krackhardt, A.M., Uckert, W., Wohlleber, D., Schiemann, M., Stemmer, K., Heikenwälder, M., Busch, D.H., Richter, G., Mann, M. and Protzer, U.
Gastroenterology 149
(4): 1042-1052.
October 2015
Hnf1b controls pancreas morphogenesis and the generation of Ngn3(+) endocrine progenitors.
De Vas, M.G., Kopp, J.L., Heliot, C., Sander, M., Cereghini, S. and Haumaitre, C.
Development 142
(5): 871-82.
March 2015
Epoxides derived from dietary dihomo-gamma-linolenic acid induce germ cell death in C. elegans.
Deline, M., Keller, J., Rothe, M., Schunck, W.H., Menzel, R. and Watts, J.L.
Scientific Reports 5
: 15417.
21 October 2015
Pharmacological targeting of AKAP-directed compartmentalized cAMP signalling.
Dema, A., Perets, E., Schulz, M.S., Deák, V.A. and Klussmann, E.
Cellular Signalling 27
(12): 2474-2487.
December 2015
A probabilistic model for estimating the depth and threshold temperature of C-fiber nociceptors.
Dezhdar, T., Moshourab, R.A., Fründ, I., Lewin, G.R. and Schmuker, M.
Scientific Reports 5
: 17670.
7 December 2015
Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner.
DiBattista, A.M., Dumanis, S.B., Song, J.M., Bu, G., Weeber, E., Rebeck, G.W. and Hoe, H.S.
Biochimica et Biophysica Acta - Molecular Cell Research 1853
(5): 904-917.
May 2015
Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells.
Dias, J.D., Rito, T., Torlai Triglia, E., Kukalev, A., Ferrai, C., Chotalia, M., Brookes, E., Kimura, H. and Pombo, A.
eLife 4
: e11215.
19 December 2015
Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.
Dick, A., Graf, L., Olal, D., von der Malsburg, A., Gao, S., Kochs, G. and Daumke, O.
Journal of Biological Chemistry 290
(20): 12779-12792.
15 May 2015
Conical Fourier shell correlation applied to electron tomograms.
Diebolder, C.A., Faas, F.G.A., Koster, A.J. and Koning, R.I.
Journal of Structural Biology 190
(2): 215-223.
May 2015
Cryoelectron tomography of the NAIP5/NLRC4 inflammasome: implications for NLR activation.
Diebolder, C.A., Halff, E.F., Koster, A.J., Huizinga, E.G. and Koning, R.I.
Structure 23
(12): 2349-2357.
1 December 2015
Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency.
Diecke, S., Lu, J., Lee, J., Termglinchan, V., Kooreman, N.G., Burridge, P.W., Ebert, A.D., Churko, J.M., Sharma, A., Kay, M.A. and Wu, J.C.
Scientific Reports 5
: 8081.
28 January 2015
Composition, formation, and regulation of the cytosolic c-ring, a dynamic component of the type III secretion injectisome.
Diepold, A., Kudryashev, M., Delalez, N.J., Berry, R.M. and Armitage, J.P.
PLoS Biology 13
(1): e1002039.
15 January 2015
Smoking, smoking cessation, and risk of tooth loss: the EPIC-Potsdam study.
Dietrich, T., Walter, C., Oluwagbemigun, K., Bergmann, M., Pischon, T., Pischon, N. and Boeing, H.
Journal of Dental Research 94
(10): 1369-1375.
October 2015
SILAC for biomarker discovery.
Dittmar, G. and Selbach, M.
Proteomics Clinical Applications 9
(3-4): 301-306.
April 2015
Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3.
Doddaballapur, A., Michalik, K.M., Manavski, Y., Lucas, T., Houtkooper, R.H., You, X., Chen, W., Zeiher, A.M., Potente, M., Dimmeler, S. and Boon, R.A.
Arteriosclerosis Thrombosis and Vascular Biology 35
(1): 137-145.
January 2015
Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy.
Domigan, C.K., Warren, C.M., Antanesian, V., Happel, K., Ziyad, S., Lee, S., Krall, A., Duan, L., Torres-Collado, A.X., Castellani, L.W., Elashoff, D., Christofk, H.R., van der Bliek, A.M., Potente, M. and Iruela-Arispe, M.L.
Journal of Cell Science 128
(12): 2236-2248.
15 June 2015
Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency.
Doss, S., Rinnenthal, J.L., Schmitz-Hübsch, T., Brandt, A.U., Papazoglou, S., Lux, S., Maul, S., Würfel, J., Endres, M., Klockgether, T., Minnerop, M. and Paul, F.
Journal of Neurology 262
(8): 1927-1935.
August 2015
Impaired myocardial development resulting in neonatal cardiac hypoplasia alters postnatal growth and stress response in the heart.
Drenckhahn, J.D., Strasen, J., Heinecke, K., Langner, P., Yin, K.V., Skole, F., Hennig, M., Spallek, B., Fischer, R., Blaschke, F., Heuser, A., Cox, T.C., Black, M.J. and Thierfelder, L.
Cardiovascular Research 106
(1): 43-54.
1 April 2015
The impact of isolated lesions on white-matter fiber tracts in multiple sclerosis patients.
Droby, A., Fleischer, V., Carnini, M., Zimmermann, H., Siffrin, V., Gawehn, J., Erb, M., Hildebrandt, A., Baier, B. and Zipp, F.
NeuroImage: Clinical 8
: 110-116.
2015
Untargeted metabolic profiling identifies altered serum metabolites of type 2 diabetes mellitus in a prospective, nested case control study.
Drogan, D., Dunn, W.B., Lin, W., Buijsse, B., Schulze, M.B., Langenberg, C., Brown, M., Floegel, A., Dietrich, S., Rolandsson, O., Wedge, D.C., Goodacre, R., Forouhi, N.G., Sharp, S.J., Spranger, J., Wareham, N.J. and Boeing, H.
Clinical Chemistry 61
(3): 487-497.
March 2015
Regional distribution of body fat in relation to DNA methylation within the LPL, ADIPOQ and PPARγ promoters in subcutaneous adipose tissue.
Drogan, D., Boeing, H., Janke, J., Schmitt, B., Zhou, Y., Walter, J., Pischon, T. and Tierling, S.
Nutrition & Diabetes 5
: e168.
6 July 2015
Angiotensin II induces skeletal muscle atrophy by activating TFEB-mediated MuRF1 expression.
Du Bois, P., Pablo Tortola, C., Lodka, D., Kny, M., Schmidt, F., Song, K., Schmidt, S., Bassel-Duby, R., Olson, E.N. and Fielitz, J.
Circulation Research 117
(5): 424-436.
14 August 2015
Distinct functions for anterograde and retrograde sorting of SORLA in amyloidogenic processes in the brain.
Dumanis, S.B., Burgert, T., Caglayan, S., Füchtbauer, A., Füchtbauer, E.M., Schmidt, V. and Willnow, T.E.
Journal of Neuroscience 35
(37): 12703-12713.
16 September 2015
Perspectives on unidirectional versus divergent transcription.
Duttke, S.H.C., Lacadie, S.A., Ibrahim, M.M., Glass, C.K., Corcoran, D.L., Benner, C., Heinz, S., Kadonaga, J.T. and Ohler, U.
Molecular Cell 60
(3): 348-349.
5 November 2015
Human promoters are intrinsically directional.
Duttke, S.H.C., Lacadie, S.A., Ibrahim, M.M., Glass, C.K., Corcoran, D.L., Benner, C., Heinz, S., Kadonaga, J.T. and Ohler, U.
Molecular Cell 57
(4): 674-684.
19 February 2015
The transition from first-line to second-line therapy in multiple sclerosis.
Dörr, J. and Paul, F.
Current Treatment Options in Neurology 17
(6): 354.
June 2015
Sex dependent differences in renal angiotensinogen as an early marker of diabetic nephropathy.
de Alencar Franco Costa, D., Todiras, M., Campos, L.A., Cipolla-Neto, J., Bader, M. and Baltatu, O.C.
Acta Physiologica 213
(3): 740-746.
March 2015
Eukaryotic plankton diversity in the sunlit ocean.
de Vargas, C., Audic, S., Henry, N., Decelle, J., Mahe, F., Logares, R., Lara, E., Berney, C., Le Bescot, N., Probert, I., Carmichael, M., Poulain, J., Romac, S., Colin, S., Aury, J.M., Bittner, L., Chaffron, S., Dunthorn, M., Engelen, S., Flegontova, O., Guidi, L., Horak, A., Jaillon, O., Lima-Mendez, G., Lukes, J., Malviya, S., Morard, R., Mulot, M., Scalco, E., Siano, R., Vincent, F., Zingone, A., Dimier, C., Picheral, M., Searson, S., Kandels-Lewis, S., Acinas, S.G., Bork, P., Bowler, C., Gorsky, G., Grimsley, N., Hingamp, P., Iudicone, D., Not, F., Ogata, H., Pesant, S., Raes, J., Sieracki, M.E., Speich, S., Stemmann, L., Sunagawa, S., Weissenbach, J., Wincker, P. and Karsenti, E.
Science 348
(6237): 1261605.
22 May 2015
The effect of CCR2 inhibitor CCX140-B on residual albuminuria in patients with type 2 diabetes and nephropathy: a randomised trial.
de Zeeuw, D., Bekker, P., Henkel, E., Hasslacher, C., Gouni-Berthold, I., Mehling, H., Potarca, A., Tesar, V., Heerspink, H.J.L. and Schall, T.J.
Lancet Diabetes & Endocrinology 3
(9): 687-696.
September 2015
E
Quantitative imaging of gut microbiota spatial organization.
Earle, K.A., Billings, G., Sigal, M., Lichtman, J.S., Hansson, G.C., Elias, J.E., Amieva, M.R., Huang, K.C. and Sonnenburg, J.L.
Cell Host & Microbe 18
(4): 478-488.
14 October 2015
Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?
Ebert, A.D., Diecke, S., Chen, I.Y. and Wu, J.C.
EMBO Molecular Medicine 7
(9): 1090-1103.
16 July 2015
Circulating insulin-like growth factor binding protein-3 predicts one-year outcome after ischemic stroke.
Ebinger, M., Ipsen, N., Leonards, C.O., Empl, L., Hanne, L., Liman, T., Mai, K., Strasburger, C.J., Spranger, J. and Endres, M.
Experimental and Clinical Endocrinology & Diabetes 123
(8): 461-465.
September 2015
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Ecker, J., Oehme, I., Mazitschek, R., Korshunov, A., Kool, M., Hielscher, T., Kiss, J., Selt, F., Konrad, C., Lodrini, M., Deubzer, H.E., von Deimling, A., Kulozik, A.E., Pfister, S.M., Witt, O. and Milde, T.
Acta Neuropathologica Communications 3
: 22.
3 April 2015
GORAB missense mutations disrupt RAB6 and ARF5 binding and golgi targeting.
Egerer, J., Emmerich, D., Fischer-Zirnsak, B., Chan, W.L., Meierhofer, D., Tuysuz, B., Marschner, K., Sauer, S., Barr, F.A., Mundlos, S. and Kornak, U.
Journal of Investigative Dermatology 135
(10): 2368-2376.
October 2015
The nicotinic acetylcholine receptor alpha 4 subunit contains a functionally relevant SNP Haplotype.
Eggert, M., Winterer, G., Wanischeck, M., Hoda, J.C., Bertrand, D. and Steinlein, O.
BMC Genetics 16
(1): 46.
2 May 2015
Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma.
Elbelt, U., Trovato, A., Kloth, M., Gentz, E., Finke, R., Spranger, J., Galas, D., Weber, S., Wolf, C., Koenig, K., Arlt, W., Buettner, R., May, P., Allolio, B. and Schneider, J.G.
Journal of Clinical Endocrinology and Metabolism 100
(1): E119-E128.
January 2015
Cholinergic pathway suppresses pulmonary innate immunity facilitating pneumonia after stroke.
Engel, O., Akyuez, L., da Costa Goncalves, A.C., Winek, K., Dames, C., Thielke, M., Herold, S., Böttcher, C., Priller, J., Volk, H.D., Dirnagl, U., Meisel, C. and Meisel, A.
Stroke 46
(11): 3232-3240.
November 2015
Maternal filaggrin mutations increase the risk of atopic dermatitis in children: an effect independent of mutation inheritance.
Esparza-Gordillo, J., Matanovic, A., Marenholz, I., Bauerfeind, A., Rohde, K., Nemat, K., Lee-Kirsch, M.A., Nordenskjöld, M., Winge, M.C.G., Keil, T., Krüger, R., Lau, S., Beyer, K., Kalb, B., Niggemann, B., Hübner, N., Cordell, H.J., Bradley, M. and Lee, Y.A.
PLoS Genetics 11
(3): e1005076.
10 March 2015
Dermcidin: a skeletal muscle myokine modulating cardiomyocyte survival and infarct size after coronary artery ligation.
Esposito, G., Schiattarella, G.G., Perrino, C., Cattaneo, F., Pironti, G., Franzone, A., Gargiulo, G., Magliulo, F., Serino, F., Carotenuto, G., Sannino, A., Ilardi, F., Scudiero, F., Brevetti, L, Oliveti, M., Giugliano, G., Del Giudice, C., Ciccarelli, M., Renzone, G., Scaloni, A., Zambrano, N. and Trimarco, B.
Cardiovascular Research 107
(4): 431-441.
1 September 2015
Matching cell type to function in cortical circuits.
Estebanez, L., Kremkow, J. and Poulet, J.F.A.
Neuron 87
(2): 249-251.
15 July 2015
Temporal retinal nerve fibre layer thinning in cluster headache patients detected by optical coherence tomography.
Ewering, C., Haşal, N., Alten, F., Clemens, C.R., Eter, N., Oberwahrenbrock, T., Kadas, E.M., Zimmermann, H., Brandt, A.U., Osada, N., Paul, F. and Marziniak, M.
Cephalalgia 35
(11): 946-958.
October 2015
F
Surveillance and Outbreak Response Management System (SORMAS) to support the control of the Ebola virus disease outbreak in West Africa.
Faehnrich, C., Denecke, K., Adeoye, O.O., Benzler, J., Claus, H., Kirchner, G., Mall, S., Richter, R., Schapranow, M.P., Schwarz, N., Tom-Aba, D., Uflacker, M., Poggensee, G. and Krause, G.
Euro Surveillance 20
(12): 1-8.
26 March 2015
Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis.
Feng, X., Szulzewsky, F., Yerevanian, A., Chen, Z., Heinzmann, D., Rasmussen, R.D., Alvarez-Garcia, V., Kim, Y., Wang, B., Tamagno, I., Zhou, H., Li, X., Kettenmann, H., Ransohoff, R.M. and Hambardzumyan, D.
Oncotarget 6
(17): 15077-15094.
20 June 2015
Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data.
Fernandez-Cuesta, L., Sun, R., Menon, R., George, J., Lorenz, S., Meza-Zepeda, L.A., Peifer, M., Plenker, D., Heuckmann, J.M., Leenders, F., Zander, T., Dahmen, I., Koker, M., Schöttle, J., Ullrich, R.T., Altmüller, J., Becker, C., Nürnberg, P., Seidel, H., Böhm, D., Göke, F., Ansén, S., Russell, P.A., Wright, G.M., Wainer, Z., Solomon, B., Petersen, I., Clement, J.H., Sänger, J., Brustugun, O.T., Helland, Å., Solberg, S., Lund-Iversen, M., Buettner, R., Wolf, J., Brambilla, E., Vingron, M., Perner, S., Haas, S.A. and Thomas, R.K.
Genome Biology 16
: 7.
5 January 2015
Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility.
Feutlinske, F., Browarski, M., Ku, M.C., Trnka, P., Waiczies, S., Niendorf, T., Stallcup, W.B., Glass, R., Krause, E. and Maritzen, T.
Nature Communications 6
: 8535.
5 October 2015
KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.
Fidzinski, P., Korotkova, T., Heidenreich, M., Maier, N., Schuetze, S., Kobler, O., Zuschratter, W., Schmitz, D., Ponomarenko, A. and Jentsch, T.J.
Nature Communications 6
: 6254.
4 February 2015
A regression-based analysis of ribosome-profiling data reveals a conserved complexity to mammalian translation.
Fields, A.P., Rodriguez, E.H., Jovanovic, M., Stern-Ginossar, N., Haas, B.J., Mertins, P., Raychowdhury, R., Hacohen, N., Carr, S.A., Ingolia, N.T., Regev, A. and Weissman, J.S.
Molecular Cell 60
(5): 816-827.
3 December 2015
Altered basal ganglia functional connectivity in multiple sclerosis patients with fatigue.
Finke, C., Schlichting, J., Papazoglou, S., Scheel, M., Freing, A., Soemmer, C., Pech, L.M., Pajkert, A., Pfueller, C.J., Wuerfel, J.T., Ploner, C., Paul, F. and Brandt, A.U.
Multiple Sclerosis Journal 21
(7): 925-934.
June 2015
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.
Finkin, S., Yuan, D., Stein, I., Taniguchi, K., Weber, A., Unger, K., Browning, J.L., Goossens, N., Nakagawa, S., Gunasekaran, G., Schwartz, M.E., Kobayashi, M., Kumada, H., Berger, M., Pappo, O., Rajewsky, K., Hoshida, Y., Karin, M., Heikenwalder, M., Ben-Neriah, Y. and Pikarsky, E.
Nature Immunology 16
(12): 1235-1244.
December 2015
Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
Fischer, U., Forster, M., Rinaldi, A., Risch, T., Sungalee, S., Warnatz, H.J., Bornhauser, B., Gombert, M., Kratsch, C., Stütz, A.M., Sultan, M., Tchinda, J., Worth, C.L., Amstislavskiy, V., Badarinarayan, N., Baruchel, A., Bartram, T., Basso, G., Canpolat, C., Cario, G., Cavé, H., Dakaj, D., Delorenzi, M., Dobay, M.P., Eckert, C., Ellinghaus, E., Eugster, S., Frismantas, V., Ginzel, S., Haas, O.A., Heidenreich, O., Hemmrich-Stanisak, G., Hezaveh, K., Höll, J.I., Hornhardt, S., Husemann, P., Kachroo, P., Kratz, C.P., Te Kronnie, G., Marovca, B., Niggli, F., McHardy, A.C., Moorman, A.V., Panzer-Grümayer, R., Petersen, B.S., Raeder, B., Ralser, M., Rosenstiel, P., Schäfer, D., Schrappe, M., Schreiber, S., Schütte, M., Stade, B., Thiele, R., von der Weid, N., Vora, A., Zaliova, M., Zhang, L., Zichner, T., Zimmermann, M., Lehrach, H., Borkhardt, A., Bourquin, J.P., Franke, A., Korbel, J.O., Stanulla, M. and Yaspo, M.L.
Nature Genetics 47
(9): 1020-1029.
September 2015
Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells.
Fishman, V.S., Shnayder, T.A., Orishchenko, K.E., Bader, M., Alenina, N. and Serov, O.L.
Cell Cycle 14
(8): 1188-1196.
15 April 2015
Child impact on family functioning: a multivariate analysis in multiplex families with children and mothers both affected by attention-deficit/hyperactivity disorder (ADHD).
Fleck, K., Jacob, C., Philipsen, A., Matthies, S., Graf, E., Hennighausen, K., Haack-Dees, B., Weyers, P., Warnke, A., Roesler, M., Retz, W., von Gontard, A., Haenig, S., Freitag, C., Sobanski, E., Schumacher-Stien, M., Poustka, L., Bliznak, L., Becker, K., Holtmann, M., Colla, M., Gentschow, L., Kappel, V., Jaite, C. and Jans, T.
Attention Deficit and Hyperactivity Disorders 7
(3): 211-223.
September 2015
RNA-Seq analysis of human trigeminal and dorsal root ganglia with a focus on chemoreceptors.
Flegel, C., Schöbel, N., Altmüller, J., Becker, C., Tannapfel, A., Hatt, H. and Gisselmann, G.
PLoS ONE 10
(6): e0128951.
2015
Characterization of the olfactory receptors expressed in human spermatozoa.
Flegel, C., Vogel, F., Hofreuter, A., Schreiner, B.S.P., Osthold, S., Veitinger, S., Becker, C., Brockmeyer, N.H., Muschol, M., Wennemuth, G., Altmüller, J., Hatt, H. and Gisselmann, G.
Frontiers in Molecular Biosciences 2
: 73.
2015
Does fludrocortisone influence autobiographical memory retrieval? A study in patients with major depression, patients with borderline personality disorder and healthy controls.
Fleischer, J., Wingenfeld, K., Kuehl, L.K., Hinkelmann, K., Roepke, S. and Otte, C.
Stress 18
(6): 718-722.
November 2015
Individual uncertainty and the uncertainty of science: the impact of perceived conflict and general self-efficacy on the perception of tentativeness and credibility of scientific information.
Flemming, D., Feinkohl, I., Cress, U. and Kimmerle, J.
Frontiers in Psychology 6
: 1859.
1 December 2015
Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken, A., Grau, M., Wolf, A., Weilemann, A., Kopp, J., Dörken, B., Blankenstein, T., Pezzutto, A., Lenz, P., Lenz, G. and Westermann, J.
International Journal of Cancer 136
(8): 1814-1826.
15 April 2015
Myeloid-derived suppressor cells in human peripheral blood: optimized quantification in healthy donors and patients with metastatic renal cell carcinoma.
Flörcken, A., Takvorian, A., Singh, A., Gerhardt, A., Ostendorf, B.N., Dörken, B., Pezzutto, A. and Westermann, J.
Immunology Letters 168
(2): 260-267.
December 2015
Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer.
Font-Burgada, J., Shalapour, S., Ramaswamy, S., Hsueh, B., Rossell, D., Umemura, A., Taniguchi, K., Nakagawa, H., Valasek, M.A., Ye, L., Kopp, J.L., Sander, M., Carter, H., Deisseroth, K., Verma, I.M. and Karin, M.
Cell 162
(4): 766-79.
13 August 2015
Assessment of curated phenotype mining in neuropsychiatric disorder literature.
Fontaine, J.F., Priller, J., Spruth, E., Perez-Iratxeta, C. and Andrade-Navarro, M.A.
Methods 74
: 90-96.
March 2015
Investigation of heart proteome of different consomic mouse strains. Testing the effect of polymorphisms on the proteome-wide trans-variation of proteins.
Forler, S., Klein, O., Koehler, S., Robinson, P.N., Witt, H., Sultan, M., Eravci, M., Regitz-Zagrosek, V., Lehrach, H. and Klose, J.
EuPA Open Proteomics 7
: 27-42.
2015
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.
Forslund, K., Hildebrandt, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H.K., Arumugam, M., Kristiansen, K., Voigt, A.Y., Vestergaard, H., Hercog, R., Costea, P.I., Kultima, J.R., Li, J., Jørgensen, T., Levenez, F., Dore, J., Nielsen, H.B., Brunak, S., Raes, J., Hansen, T., Wang, J., Ehrlich, S.D., Bork, P. and Pedersen, O.
Nature 528
(7581): 262-266.
10 December 2015
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.
Fossati, G., Morini, R., Corradini, I., Antonucci, F., Trepte, P., Edry, E., Sharma, V., Papale, A., Pozzi, D., Defilippi, P., Meier, J.C., Brambilla, R., Turco, E., Rosenblum, K., Wanker, E.E., Ziv, N.E., Menna, E. and Matteoli, M.
Cell Death and Differentiation 22
(9): 1425-1436.
September 2015
Endothelial alpha-parvin controls integrity of developing vasculature and is required for maintenance of cell-cell junctions.
Fraccaroli, A., Pitter, B., Taha, A.A., Seebach, J., Huveneers, S., Kirsch, J., Casaroli-Marano, R.P., Zahler, S., Pohl, U., Gerhardt, H., Schnittler, H.J. and Montanez, E.
Circulation Research 117
(1): 29-40.
19 June 2015
An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.
Frahm, S., Antolin-Fontes, B., Goerlich, A., Zander, J.F., Ahnert-Hilger, G. and Ibanez-Tallon, I.
eLife 4
: e11396.
1 December 2015
Dynamic endothelial cell rearrangements drive developmental vessel regression.
Franco, C.A., Jones, M.L., Bernabeu, M.O., Geudens, I., Mathivet, T., Rosa, A., Lopes, F.M., Lima, A.P., Ragab, A., Collins, R.T., Phng, L.K., Coveney, P.V. and Gerhardt, H.
PLoS Biology 13
(4): e1002125.
17 April 2015
Photoswitchable fatty acids enable optical control of TRPV1.
Frank, J.A., Moroni, M., Moshourab, R., Sumser, M., Lewin, G.R. and Trauner, D.
Nature Communications 6
: 7118.
21 May 2015
Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation.
Fraser, J., Ferrai, C., Chiariello, A.M., Schueler, M., Rito, T., Laudanno, G., Barbieri, M., Moore, B.L., Kraemer, D.C.A., Aitken, S., Xie, S.Q., Morris, K.J., Itoh, M., Kawaji, H., Jaeger, I., Hayashizaki, Y., Carninci, P., Forrest, A.R.R., Semple, C.A., Dostie, J., Pombo, A. and Nicodemi, M.
Molecular Systems Biology 11
(12): 852.
23 December 2015
The impact of age on the benefits and risks of aliskiren treatment: analyses of the 3A registry.
Friedrich, S., Zeymer, U., Dechend, R., Hagedorn, I., Riemer, T., Zemmrich, C., Bramlage, P., Pittrow, D., Senges, J. and Schmieder, R.E.
Journal of Human Hypertension 29
(5): 316-323.
May 2015
Hypertrophe und restriktive Kardiomyopathie : Differenzierung mittels Bildgebung [Hypertrophic and restrictive cardiomyopathy : differentiation by imaging].
Fritschi, S., Prothmann, M. and Schulz-Menger, J.
Herz 40
(4): 591-599.
1 June 2015
Immunofluorescence analysis and diagnosis of primary ciliary dyskinesia with radial spoke defects.
Frommer, A., Hjeij, R., Loges, N.T., Edelbusch, C., Jahnke, C., Raidt, J., Werner, C., Wallmeier, J., Große-Onnebrink, J., Olbrich, H., Cindrić, S., Jaspers, M., Boon, M., Memari, Y., Durbin, R., Kolb-Kokocinski, A., Sauer, S., Marthin, J.K., Nielsen, K.G., Amirav, I., Elias, N., Kerem, E., Shoseyov, D., Haeffner, K. and Omran, H.
American Journal of Respiratory Cell and Molecular Biology 53
(4): 563-573.
1 October 2015
Amorfrutins are natural PPARγ agonists with potent anti-inflammatory properties.
Fuhr, L., Rousseau, M., Plauth, A., Schroeder, F.C. and Sauer, S.
Journal of Natural Products 78
(5): 1160-1164.
22 May 2015
G
Importin-α7 is involved in the formation of Ebola virus inclusion bodies but is not essential for pathogenicity in mice.
Gabriel, G., Feldmann, F., Reimer, R., Thiele, S., Fischer, M., Hartmann, E., Bader, M., Ebihara, H., Hoenen, T. and Feldmann, H.
Journal of Infectious Diseases 212
(Suppl 2): S316-S321.
1 October 2015
CHD2 variants are a risk factor for photosensitivity in epilepsy.
Galizia, E.C., Myers, C.T., Leu, C., de Kovel, C.G.F., Afrikanova, T., Cordero-Maldonado, M.L., Martins, T.G., Jacmin, M., Drury, S., Krishna Chinthapalli, V., Muhle, H., Pendziwiat, M., Sander, T., Ruppert, A.K., Møller, R.S., Thiele, H., Krause, R., Schubert, J., Lehesjoki, A.E., Nürnberg, P., Lerche, H., Palotie, A., Coppola, A., Striano, S., Gaudio, L.D., Boustred, C., Schneider, A.L., Lench, N., Jocic-Jakubi, B., Covanis, A., Capovilla, G., Veggiotti, P., Piccioli, M., Parisi, P., Cantonetti, L., Sadleir, L.G., Mullen, S.A., Berkovic, S.F, Stephani, U., Helbig, I., Crawford, A.D., Esguerra, C.V., Kasteleijn-Nolst Trenité, D.G.A., Koeleman, B.P.C., Mefford, H.C., Scheffer, I.E. and Sisodiya, S.M.
Brain 138
(5): 1198-1207.
May 2015
151 years Berliner Klinische Wochenschrift and the 20th anniversary of the Journal of Molecular Medicine.
Ganten, D., Semenza, G. and Sommer, T.
Journal of Molecular Medicine 93
(9): 935-936.
September 2015
Modulation of human IAPP fibrillation: cosolutes, crowders and chaperones.
Gao, M., Estel, K., Seeliger, J., Friedrich, R.P., Dogan, S., Wanker, E.E., Winter, R. and Ebbinghaus, S.
Physical Chemistry Chemical Physics 17
(13): 8338-8348.
7 April 2015
Predominant contribution of cis-regulatory divergence in the evolution of mouse alternative splicing.
Gao, Q., Sun, W., Ballegeer, M., Libert, C. and Chen, W.
Molecular Systems Biology 11
(7): 816.
1 July 2015
Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors.
Garrett, L., Zhang, J., Zimprich, A., Niedermeier, K.M., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Vogt Weisenhorn, D., Wurst, W. and Hoelter, S.M.
Frontiers in Behavioral Neuroscience 9
: 302.
12 November 2015
mBISON: Finding miRNA target over-representation in gene lists from ChIP-sequencing data.
Gebhardt, M.L., Mer, A.S. and Andrade-Navarro, M.A.
BMC Research Notes 8
(1): 157.
16 April 2015
New role for the (pro)renin receptor in T cell development.
Geisberger, S., Maschke, U., Gebhardt, M., Kleinewietfeld, M., Manzel, A., Linker, R.A., Chidgey, A., Dechend, R., Nguyen, G., Daumke, O., Muller, D.N., Wright, M.D. and Binger, K.J.
Blood 126
(4): 504-507.
23 July 2015
Comprehensive genomic profiles of small cell lung cancer.
George, J., Lim, J.S., Jang, S.J., Cun, Y., Ozretić, L., Kong, G., Leenders, F., Lu, X., Fernández-Cuesta, L., Bosco, G., Müller, C., Dahmen, I., Jahchan, N.S., Park, K.S., Yang, D., Karnezis, A.N., Vaka, D., Torres, A., Wang, M.S., Korbel, J.O., Menon, R., Chun, S.M., Kim, D., Wilkerson, M., Hayes, N., Engelmann, D., Pützer, B., Bos, M., Michels, S., Vlasic, I., Seidel, D., Pinther, B., Schaub, P., Becker, C., Altmüller, J., Yokota, J., Kohno, T., Iwakawa, R., Tsuta, K., Noguchi, M., Muley, T., Hoffmann, H., Schnabel, P.A., Petersen, I., Chen, Y., Soltermann, A., Tischler, V., Choi, C.M., Kim, Y.H., Massion, P.P., Zou, Y., Jovanovic, D., Kontic, M., Wright, G.M., Russell, P.A., Solomon, B., Koch, I., Lindner, M., Muscarella, L.A., la Torre, A., Field, J.K., Jakopovic, M., Knezevic, J., Castaños-Vélez, E., Roz, L., Pastorino, U., Brustugun, O.T., Lund-Iversen, M., Thunnissen, E., Köhler, J., Schuler, M., Botling, J., Sandelin, M., Sanchez-Cespedes, M., Salvesen, H.B., Achter, V., Lang, U., Bogus, M., Schneider, P.M., Zander, T., Ansén, S., Hallek, M., Wolf, J., Vingron, M., Yatabe, Y., Travis, W.D., Nürnberg, P., Reinhardt, C., Perner, S., Heukamp, L., Büttner, R., Haas, S.A., Brambilla, E., Peifer, M., Sage, J. and Thomas, R.K.
Nature 524
(7563): 47-53.
6 August 2015
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Ghorashian, S., Veliça, P., Chua, I., McNicol, A., Carpenter, B., Holler, A., Nicholson, E., Ahmadi, M., Zech, M., Xue, S., Uckert, W., Morris, E., Chakraverty, R. and Stauss, H.J.
Journal of Immunology 194
(3): 1080-1089.
1 February 2015
Regional differences in perivascular adipose tissue impacting vascular homeostasis.
Gil-Ortega, M., Somoza, B., Huang, Y., Gollasch, M. and Fernández-Alfonso, M.S.
Trends in Endocrinology and Metabolism 26
(7): 367-375.
July 2015
Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins.
Gimber, N., Tadeus, G., Maritzen, T., Schmoranzer, J. and Haucke, V.
Nature Communications 6
: 8392.
24 September 2015
Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion.
Giordano, M., Henin, C., Maurizio, J., Imbratta, C., Bourdely, P., Buferne, M., Baitsch, L., Vanhille, L., Sieweke, M.H., Speiser, D.E., Auphan-Anezin, N., Schmitt-Verhulst, A.M. and Verdeil, G.
EMBO Journal 34
(15): 2042-2058.
4 August 2015
2D and 3D similarity landscape analysis identifies PARP as a novel off-target for the drug Vatalanib.
Gohlke, B.O., Overkamp, T., Richter, A., Richter, A., Daniel, P.T., Gillissen, B. and Preissner, R.
BMC Bioinformatics 16
(1): 308.
24 September 2015
Identification of a novel mutation in RIPK4 in a kindred with phenotypic features of Bartsocas-Papas and CHAND syndromes.
Gollasch, B., Basmanav, F.B., Nanda, A., Fritz, G., Mahmoudi, H., Thiele, H., Wehner, M., Wolf, S., Altmüller, J., Nürnberg, P., Frank, J. and Betz, R.C.
American Journal of Medical Genetics Part A 167
(11): 2555-2562.
November 2015
Allergic multimorbidity of asthma, rhinitis, and eczema over 20 years in the German birth cohort MAS.
Gough, H., Grabenhenrich, L., Reich, A., Eckers, N., Nitsche, O., Schramm, D., Beschorner, J., Hoffmann, U., Schuster, A., Bauer, C.P., Forster, J., Zepp, F., Lee, Y.A., Bergmann, R.L., Bergmann, K.E., Wahn, U., Lau, S. and Keil, T.
Pediatric Allergy and Immunology 26
(5): 431-437.
August 2015
The route to spinal cord cell types: a tale of signals and switches.
Gouti, M., Metzis, V. and Briscoe, J.
Trends in Genetics 31
(6): 282-289.
June 2015
Prediction and prevention of allergic rhinitis: A birth cohort study of 20 years.
Grabenhenrich, L.B., Keil, T., Reich, A., Gough, H., Beschorner, J., Hoffmann, U., Bauer, C.P., Forster, J., Schuster, A., Schramm, D., Nitsche, O., Zepp, F., Lee, Y.A., Bergmann, R., Bergmann, K., Wahn, U. and Lau, S.
Journal of Allergy and Clinical Immunology 136
(4): 932-940.
October 2015
Sodium MRI of the human heart at 7.0 T: preliminary results.
Graessl, A., Ruehle, A., Waiczies, H., Resetar, A., Hoffmann, S.H., Rieger, J., Wetterling, F., Winter, L., Nagel, A.M. and Niendorf, T.
NMR in Biomedicine 28
(8): 967-975.
August 2015
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Grajales-Reyes, G.E., Iwata, A., Albring, J., Wu, X., Tussiwand, R., Kc, W., Kretzer, N.M., Briseno, C.G., Durai, V., Bagadia, P., Haldar, M., Schoenheit, J., Rosenbauer, F., Murphy, T.L. and Murphy, K.M.
Nature Immunology 16
(7): 708-717.
July 2015
Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy.
Gramlich, M., Pane, L.S., Zhou, Q., Chen, Z., Murgia, M., Schoetterl, S., Goedel, A., Metzger, K., Brade, T., Parrotta, E., Schaller, M., Gerull, B., Thierfelder, L., Aartsma-Rus, A., Labeit, S., Atherton, J.J., McGaughran, J., Harvey, R.P., Sinnecker, D., Mann, M., Laugwitz, K.L., Gawaz, M.P. and Moretti, A.
EMBO Molecular Medicine 7
(5): 562-576.
10 March 2015
Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites.
Grandi, F.C., Rosser, J.M., Newkirk, S.J., Yin, J., Jiang, X., Xing, Z., Whitmore, L., Bashir, S., Ivics, Z., Izsvák, Z., Ye, P., Yu, Y.E. and An, W.
Genome Research 25
(8): 1135-1146.
August 2015
Characterization of panglial gap junction networks in the thalamus, neocortex, and hippocampus reveals a unique population of glial cells.
Griemsmann, S., Höft, S.P., Bedner, P., Zhang, J., von Staden, E., Beinhauer, A., Degen, J., Dublin, P., Cope, D.W., Richter, N., Crunelli, V., Jabs, R., Willecke, K., Theis, M., Seifert, G., Kettenmann, H. and Steinhäuser, C.
Cerebral Cortex 25
(10): 3420-3433.
October 2015
Molecular signaling mechanisms of axon-glia communication in the peripheral nervous system.
Grigoryan, T. and Birchmeier, W.
BioEssays 37
(5): 502-513.
May 2015
Monitoring hemodynamics and oxygenation of the kidney in rats by a combined near-infrared spectroscopy and invasive probe approach.
Grosenick, D., Cantow, K., Arakelyan, K., Wabnitz, H., Flemming, B., Skalweit, A., Ladwig, M., Macdonald, R., Niendorf, T. and Seeliger, E.
In: UNSPECIFIED.
16 July 2015
Characterization of hemodynamics and oxygenation in the renal cortex of rats.
Grosenick, D., Wabnitz, H., Macdonald, R., Niendorf, T., Cantow, K., Flemming, B., Arakelyan, K. and Seeliger, E.
In: UNSPECIFIED.
5 March 2015
Detailing renal hemodynamics and oxygenation in rats by a combined near-infrared spectroscopy and invasive probe approach.
Grosenick, D., Cantow, K., Arakelyan, K., Wabnitz, H., Flemming, B., Skalweit, A., Ladwig, M., Macdonald, R., Niendorf, T. and Seeliger, E.
Biomedical Optics Express 6
(2): 309-323.
1 February 2015
Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.
Grosskopf, S., Eckert, C., Arkona, C., Radetzki, S., Böhm, K., Heinemann, U., Wolber, G., von Kries, J.P., Birchmeier, W. and Rademann, J.
ChemMedChem 10
(5): 815-826.
May 2015
Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism.
Gu, M., Mordwinkin, N.M., Kooreman, N.G., Lee, J., Wu, H., Hu, S., Churko, J.M., Diecke, S., Burridge, P.W., He, C., Barron, F.E., Ong, S.G., Gold, J.D. and Wu, J.C
European Heart Journal 36
(13): 806-16.
1 April 2015
Receptors, G proteins, and integration of calcium signalling.
Gudermann, T. and Bader, M.
Journal of Molecular Medicine 93
(9): 937-940.
September 2015
A protocol for chemical mutagenesis in Strongyloides ratti.
Guo, L., Chang, Z., Dieterich, C. and Streit, A.
Experimental Parasitology 158
: 2-7.
November 2015
Quantification of the transmural dynamics of atrial fibrillation by simultaneous endocardial and epicardial optical mapping in an acute sheep model.
Gutbrod, S.R., Walton, R., Gilbert, S., Meillet, V., Jais, P., Hocini, M., Haissaguerre, M., Dubois, R., Bernus, O. and Efimov, I.
Circulation Arrhythmia and Electrophysiology 8
(2): 456-465.
April 2015
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.
Günther, C., Kind, B., Reijns, M.A.M., Berndt, N., Martinez-Bueno, M., Wolf, C., Tüngler, V., Chara, O., Lee, Y.A., Hübner, N., Bicknell, L., Blum, S., Krug, C., Schmidt, F., Kretschmer, S., Koss, S., Astell, K.R., Ramantani, G., Bauerfeind, A., Morris, D.L., Cunninghame Graham, D.S., Bubeck, D., Leitch, A., Ralston, S.H., Blackburn, E.A., Gahr, M., Witte, T., Vyse, T.J., Melchers, I., Mangold, E., Nöthen, M.M., Aringer, M., Kuhn, A., Lüthke, K., Unger, L., Bley, A., Lorenzi, A., Isaacs, J.D., Alexopoulou, D., Conrad, K., Dahl, A., Roers, A., Alarcon-Riquelme, M.E., Jackson, A.P. and Lee-Kirsch, M.A.
Journal of Clinical Investigation 125
(1): 413-424.
2 January 2015
H
Spatio-temporal model of endogenous ROS and raft-dependent WNT/β-catenin signaling driving cell fate commitment in human neural progenitor cells.
Haack, F., Lemcke, H., Ewald, R., Rharass, T. and Uhrmacher, A.M.
PLoS Computational Biology 11
(3): e1004106.
20 March 2015
Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement.
Haack, T.B., Jackson, C.B., Murayama, K., Kremer, L.S., Schaller, A., Kotzaeridou, U., de Vries, M.C., Schottmann, G., Santra, S., Büchner, B., Wieland, T., Graf, E., Freisinger, P., Eggimann, S., Ohtake, A., Okazaki, Y., Kohda, M., Kishita, Y., Tokuzawa, Y., Sauer, S., Memari, Y., Kolb-Kokocinski, A., Durbin, R., Hasselmann, O., Cremer, K., Albrecht, B., Wieczorek, D., Engels, H., Hahn, D., Zink, A.M., Alston, C.L., Taylor, R.W., Rodenburg, R.J., Trollmann, R., Sperl, W., Strom, T.M., Hoffmann, G.F., Mayr, J.A., Meitinger, T., Bolognini, R., Schuelke, M., Nuoffer, J.M., Kölker, S., Prokisch, H. and Klopstock, T.
Annals of Clinical and Translational Neurology 2
(5): 492-509.
May 2015
Welche Bedeutung haben die Ernaehrungswissenschaften fuer die Behandlung der Anorexia nervosa? [Nutrition sciences in the treatment of eating disorders].
Haas, V. and Boschmann, M.
Psychotherapie Psychosomatik Medizinische Psychologie 65
(1): 33-35.
January 2015
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors.
Haas, S., Hansson, J., Klimmeck, D., Loeffler, D., Velten, L., Uckelmann, H., Wurzer, S., Prendergast, Á.M., Schnell, A., Hexel, K., Santarella-Mellwig, R., Blaszkiewicz, S., Kuck, A., Geiger, H., Milsom, M.D., Steinmetz, L.M., Schroeder, T., Trumpp, A., Krijgsveld, J. and Essers, M.A.G.
Cell Stem Cell 17
(4): 422-34.
1 October 2015
miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.
Haftmann, C., Stittrich, A.B., Zimmermann, J., Fang, Z., Hradilkova, K., Bardua, M., Westendorf, K., Heinz, G.A., Riedel, R., Siede, J., Lehmann, K., Weinberger, E.E., Zimmel, D., Lauer, U., Häupl, T., Sieper, J., Backhaus, M., Neumann, C., Hoffmann, U., Porstner, M., Chen, W., Grün, J.R., Baumgrass, R., Matz, M., Löhning, M., Scheffold, A., Wittmann, J., Chang, H.D., Rajewsky, N., Jäck, H.M., Radbruch, A. and Mashreghi, M.F.
European Journal of Immunology 45
(4): 1192-1205.
April 2015
Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine.
Haghikia, A., Jörg, S., Duscha, A., Berg, J., Manzel, A., Waschbisch, A., Hammer, A., Lee, D.H., May, C., Wilck, N., Balogh, A., Ostermann, A.I., Schebb, N.H., Akkad, D.A., Grohme, D.A., Kleinewietfeld, M., Kempa, S., Thöne, J., Demir, S., Müller, D.N., Gold, R. and Linker, R.A.
Immunity 43
(4): 817-829.
20 October 2015
Diffusion maps for high-dimensional single-cell analysis of differentiation data.
Haghverdi, L., Buettner, F. and Theis, F.J.
Bioinformatics 31
(18): 2989-2998.
15 September 2015
Beyond gene inactivation: evolution of tools for analysis of serotonergic circuitry.
Hainer, C., Mosienko, V., Koutsikou, S., Crook, J.J., Gloss, B., Kasparov, S., Lumb, B.M. and Alenina, N.
ACS Chemical Neuroscience 6
(7): 1116-1129.
15 July 2015
(23)Na magnetic resonance imaging of the lower leg of acute heart failure patients during diuretic treatment.
Hammon, M., Grossmann, S., Linz, P., Kopp, C., Dahlmann, A., Garlichs, C., Janka, R., Cavallaro, A., Luft, F.C., Uder, M. and Titze, J.
PLoS ONE 10
(10): e0141336.
26 October 2015
GABA blocks pathological but not acute TRPV1 pain signals.
Hanack, C., Moroni, M., Lima, W.C., Wende, H., Kirchner, M., Adelfinger, L., Schrenk-Siemens, K., Tappe-Theodor, A., Wetzel, C., Kuich, P.H., Gassmann, M., Roggenkamp, D., Bettler, B., Lewin, G.R., Selbach, M. and Siemens, J.
Cell 160
(4): 759-770.
12 February 2015
A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4.
Hansen, M.T., Forst, B., Cremers, N., Quagliata, L., Ambartsumian, N., Grum-Schwensen, B., Klingelhoefer, J., Abdul-Al, A., Herrmann, P., Osterland, M., Stein, U., Nielsen, G.H., Scherer, P.E., Lukanidin, E., Sleeman, J.P. and Grigorian, M.
Oncogene 34
(4): 424-435.
22 January 2015
Assembling kidney tissues from cells: the long road from organoids to organs.
Hariharan, K., Kurtz, A. and Schmidt-Ott, K.M.
Frontiers in Cell and Developmental Biology 3
: 70.
11 November 2015
IL-10 supplementation increases Tregs and decreases hypertension in the RUPP rat model of preeclampsia.
Harmon, A., Cornelius, D., Amaral, L., Paige, A., Herse, F., Ibrahim, T., Wallukat, G., Faulkner, J., Moseley, J., Dechend, R. and LaMarca, B.
Hypertension in Pregnancy 34
(3): 291-306.
August 2015
Axonal damage in papilledema linked to idiopathic intracranial hypertension as revealed by multifocal visual evoked potentials.
Hartmann, C.J., Klistorner, A.I., Brandt, A.U., Schroeder, K., Kolbe, R., Cohn, E., Goebels, N., Guthoff, R., Aktas, O., Hartung, H.P. and Albrecht, P.
Clinical Neurophysiology 126
(10): 2040-2041.
October 2015
Crosstalk between two bZIP signaling pathways orchestrates salt-induced metabolic reprogramming in arabidopsis roots.
Hartmann, L., Pedrotti, L., Weiste, C., Fekete, A., Schierstaedt, J., Göttler, J., Kempa, S., Krischke, M., Dietrich, K., Mueller, M.J., Vicente-Carbajosa, J., Hanson, J. and Dröge-Laser, W.
Plant Cell 27
(8): 2244-2260.
August 2015
Differential response of the natriuretic peptide system to weight loss and exercise in overweight or obese patients.
Haufe, S., Kaminski, J., Utz, W., Haas, V., Mähler, A., Daniels, M.A., Birkenfeld, A.L., Lichtinghagen, R., Luft, F.C., Schulz-Menger, J., Engeli, S. and Jordan, J.
Journal of Hypertension 33
(7): 1458-1464.
July 2015
B cell localization and migration in health and disease.
Hauser, A.E. and Höpken, U.E.
In:
Molecular Biology of B Cells.
Academic Press, 187-214.
ISBN 978-0-12-397933-9
2015
Clinical and genetic findings in a family with NMNAT1-associated Leber congenital amaurosis: case report and review of the literature.
Hedergott, A., Volk, A.E., Herkenrath, P., Thiele, H., Fricke, J., Altmüller, J., Nürnberg, P., Kubisch, C. and Neugebauer, A.
Graefes Archive for Clinical and Experimental Ophthalmology 253
(12): 2239-2246.
December 2015
PLD3 in non-familial Alzheimer's disease.
Heilmann, S., Drichel, D., Clarimon, J., Fernández, V., Lacour, A., Wagner, H., Thelen, M., Hernández, I., Fortea, J., Alegret, M., Blesa, R., Mauleón, A., Roca, M.R., Kornhuber, J., Peters, O., Heun, R., Frölich, L., Hüll, M., Heneka, M.T., Rüther, E., Riedel-Heller, S., Scherer, M., Wiltfang, J., Jessen, F., Becker, T., Tárraga, L., Boada, M., Maier, W., Lleó, A., Ruiz, A., Nöthen, M.M. and Ramirez, A.
Nature 520
(7545): E3-E5.
2 April 2015
Imaging of autoimmune encephalitis - relevance for clinical practice and hippocampal function.
Heine, J., Prüss, H., Bartsch, T., Ploner, C.J., Paul, F. and Finke, C.
Neuroscience 309
: 68-83.
19 November 2015
histoneHMM: Differential analysis of histone modifications with broad genomic footprints.
Heinig, M., Colomé-Tatché, M., Taudt, A., Rintisch, C., Schafer, S., Pravenec, M., Hubner, N., Vingron, M. and Johannes, F.
BMC Bioinformatics 16
: 60.
22 February 2015
In vivo reprogramming for tissue repair.
Heinrichs, C., Spagnoli, F.M. and Berninger, B.
Nature Cell Biology 17
(3): 204-211.
27 February 2015
Direct inhibition of retinoic acid catabolism by fluoxetine.
Hellmann-Regen, J., Uhlemann, R., Regen, F., Heuser, I., Otte, C., Endres, M., Gertz, K. and Kronenberg, G.
Journal of Neural Transmission 122
(9): 1329-1338.
September 2015
Allogeneic stem cell transplantation for refractory acute myeloid leukemia: a single center analysis of long-term outcome.
Hemmati, P.G., Terwey, T.H., Na, I.K., Jehn, C.F., le Coutre, P., Vuong, L.G., Doerken, B. and Arnold, R.
European Journal of Haematology 95
(6): 498-506.
December 2015
Impact of early remission by induction therapy on allogeneic stem cell transplantation for acute myeloid leukemia with an intermediate risk karyotype in first complete remission.
Hemmati, P.G., Terwey, T.H., Na, I.K., le Coutre, P., Jehn, C.F., Vuong, L.G., Dörken, B. and Arnold, R.
European Journal of Haematology 94
(5): 431-438.
May 2015
Genomic DNA transposition induced by human PGBD5.
Henssen, A.G., Henaff, E., Jiang, E., Eisenberg, A.R., Carson, J.R., Villasante, C.M., Ray, M., Still, E., Burns, M., Gandara, J., Feschotte, C., Mason, C.E. and Kentsis, A.
eLife 4
: e10565.
25 September 2015
Novel candidate genes for impaired nephron development in a rat model with inherited nephron deficit and albuminuria.
Herlan, L., Schulz, A., Schulte, L., Schulz, H., Hübner, N. and Kreutz, R.
Clinical and Experimental Pharmacology and Physiology 42
(10): 1051-1058.
October 2015
Neurochondrin is an atypical RIIα-specific A-kinase anchoring protein.
Hermann, J.S., Skroblin, P., Bertinetti, D., Hanold, L.E., von der Heide, E.K., Wagener, E.M., Zenn, H.M., Klussmann, E., Kennedy, E.J. and Herberg, F.W.
Biochimica et Biophysica Acta - Proteins and Proteomics 1854
(10 Pt B): 1667-1675.
October 2015
Genomic landscape of rat strain and substrain variation.
Hermsen, R., de Ligt, J., Spee, W., Blokzijl, F., Schäfer, S., Adami, E., Boymans, S., Flink, S, van Boxtel, R., van der Weide, R.H., Aitman, T., Hübner, N., Simonis, M., Tabakoff, B., Guryev, V. and Cuppen, E.
BMC Genomics 16
: 357.
6 May 2015
CO(2) in the spotlight.
Hernandez-Miranda, L.R. and Birchmeier, C.
eLife 4
: e08086.
13 May 2015
Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis, and epicanthus inversus syndrome.
Heude, É., Bellessort, B., Fontaine, A., Hamazaki, M., Treier, A.C., Treier, M., Levi, G. and Narboux-Neme, N.
Human Molecular Genetics 24
(6): 1670-1681.
15 March 2015
No evidence for retinal damage evolving from reduced retinal blood flow in carotid artery disease.
Heßler, H., Zimmermann, H., Oberwahrenbrock, T., Kadas, E.M., Mikolajczak, J., Brandt, A.U., Kauert, A., Paul, F. and Schreiber, S.J.
BioMed Research International 2015
: 604028.
2015
Stimulation of the mineralocorticoid receptor improves memory in young and elderly healthy individuals.
Hinkelmann, K., Wingenfeld, K., Kuehl, L.K., Fleischer, J., Heuser, I., Wiedemann, K. and Otte, C.
Neurobiology of Aging 36
(2): 919-924.
February 2015
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.
Hinson, J.T., Chopra, A., Nafissi, N., Polacheck, W.J., Benson, C.C., Swist, S., Gorham, J., Yang, L., Schafer, S., Sheng, C.C., Haghighi, A., Homsy, J., Hubner, N., Church, G., Cook, S.A., Linke, W.A., Chen, C.S., Seidman, J.G. and Seidman, C.E.
Science 349
(6251): 982-986.
28 August 2015
Quantitative motor assessment of muscular weakness in myasthenia gravis: a pilot study.
Hoffmann, S., Siedler, J., Brandt, A.U., Piper, S.K., Kohler, S., Sass, C., Paul, F., Reilmann, R. and Meisel, A.
BMC Neurology 15
(1): 265.
23 December 2015
Vascular signal transducer and activator of transcription-3 promotes angiogenesis and neuroplasticity long-term after stroke.
Hoffmann, C.J., Harms, U., Rex, A., Szulzewsky, F., Wolf, S.A., Grittner, U., Lättig-Tünnemann, G., Sendtner, M., Kettenmann, H., Dirnagl, U., Endres, M. and Harms, C.
Circulation 131
(20): 1772-1782.
19 May 2015
Significant reduction in helicobacter pylori load in humans with non-viable lactobacillus reuteri DSM17648: A pilot study.
Holz, C., Busjahn, A., Mehling, H., Arya, S., Boettner, M., Habibi, H. and Lang, C.
Probiotics and Antimicrobial Proteins 7
(2): 91-100.
June 2015
Durchfuehrung und Befundung der kardialen Magnetresonanztomographie (Kardio-MRT): Positionspapier der Deutschen Gesellschaft fuer Kardiologie - Herz- und Kreislaufforschung [Performance and appraisal of cardiac magnetic resonance imaging (cardio-MRI): position paper of the German Cardiac Society].
Hombach, V., Kelle, S., Gebker, R., Nagel, E., Thiele, H., Schulz-Menger, J., Bruder, O., Fleck, E., Katus, H.A. and Kelm, M.
Kardiologe 9
(5): 337-347.
October 2015
New candidates for CD4 T cell pathogenicity in experimental neuroinflammation and multiple sclerosis.
Hoppmann, N., Graetz, C., Paterka, M., Poisa-Beiro, L., Larochelle, C., Hasan, M., Lill, C.M., Zipp, F. and Siffrin, V.
Brain 138
(Pt 4): 902-917.
April 2015
Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation.
Horbelt, D., Boergermann, J.H., Chaikuad, A., Alfano, I., Williams, E., Lukonin, I., Timmel, T., Bullock, A.N. and Knaus, P.
Journal of Biological Chemistry 290
(6): 3390-3404.
6 February 2015
Genome-wide CNV analysis in 221 unrelated patients and targeted high-throughput sequencing reveal novel causative candidate genes for colorectal adenomatous polyposis.
Horpaopan, S., Spier, I., Zink, A.M., Altmüller, J., Holzapfel, S., Laner, A., Vogt, S., Uhlhaas, S., Heilmann, S., Stienen, D., Pasternack, S.M., Keppler, K., Adam, R., Kayser, K., Moebus, S., Draaken, M., Degenhardt, F., Engels, H., Hofmann, A., Nöthen, M.M., Steinke, V., Perez-Bouza, A., Herms, S., Holinski-Feder, E., Fröhlich, H., Thiele, H., Hoffmann, P. and Aretz, S.
International Journal of Cancer 136
(6): E578–E589.
15 March 2015
Quantitative interaction proteomics of neurodegenerative disease proteins.
Hosp, F., Vossfeldt, H., Heinig, M., Vasiljevic, D., Arumughan, A., Wyler, E., Landthaler, M., Hubner, N., Wanker, E.E., Lannfelt, L., Ingelsson, M., Lalowski, M., Voigt, A. and Selbach, M.
Cell Reports 11
(7): 1134-1146.
19 May 2015
Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks.
Hossini, A.M., Megges, M., Prigione, A., Lichtner, B., Toliat, M.R., Wruck, W., Schroeter, F., Nuernberg, P., Kroll, H., Makrantonaki, E., Zoubouliss, C.C. and Adjaye, J.
BMC Genomics 16
(1): 84.
14 February 2015
Extensive allele-specific translational regulation in hybrid mice.
Hou, J., Wang, X., McShane, E., Zauber, H., Sun, W., Selbach, M. and Chen, W.
Molecular Systems Biology 11
(8): 825.
7 August 2015
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F., a Dzaye, O.D., Hahn, A., Yu, Y., Scavetta, R.J., Dittmar, G., Kaczmarek, A.K., Dunning, K.R., Ricciardelli, C., Rinnenthal, J.L., Heppner, F.L., Lehnardt, S., Synowitz, M., Wolf, S.A. and Kettenmann, H.
Neuro-Oncology 17
(2): 200-210.
February 2015
Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.
Hu, Y.C., Nicholls, P.K., Soh, Y.Q.S., Daniele, J.R., Junker, J.P., van Oudenaarden, A. and Page, D.C.
PLoS Genetics 11
(3): e1005019.
4 March 2015
eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues.
Huang, J., Chen, J., Esparza, J., Ding, J., Elder, J.T., Abecasis, G.R., Lee, Y.A., Lathrop, G.M., Moffatt, M.F., Cookson, W.O.C. and Liang, L.
Nature Communications 6
: 6821.
8 May 2015
Chemodetection and destruction of host urea allows Helicobacter pylori to locate the epithelium.
Huang, J.Y., Sweeney Goers, E., Sigal, M., Zhang, H.C., Remington, S.J., Cantrell, M.A., Kuo, C.J., Guillemin, K. and Amieva, M.R.
Cell Host & Microbe 18
(2): 147-156.
12 August 2015
Regulation of vascular tone and arterial blood pressure: role of chloride transport in vascular smooth muscle.
Huebner, C.A., Schroeder, B.C. and Ehmke, H.
Pfluegers Archiv European Journal of Physiology 467
(3): 605-614.
16 January 2015
Optical coherence tomography in patients with a history of juvenile multiple sclerosis reveals early retinal damage.
Huhn, K., Lämmer, R., Oberwahrenbrock, T., Lämmer, A., Waschbisch, A., Gosar, D., Brandt, A., Paul, F., Linker, R.A. and Lee, D.H.
European Journal of Neurology 22
(1): 86-92.
January 2015
De novo FUS mutations are the most frequent genetic cause in early-onset German ALS patients.
Hübers, A., Just, W., Rosenbohm, A., Müller, K., Marroquin, N., Goebel, I., Högel, J., Thiele, H., Altmüller, J., Nürnberg, P., Weishaupt, J.H., Kubisch, C., Ludolph, A.C. and Volk, A.E.
Neurobiology of Aging 36
(11): 3117.e1-3117.e6.
November 2015
I
JAMM: a peak finder for joint analysis of NGS replicates.
Ibrahim, M.M., Lacadie, S.A. and Ohler, U.
Bioinformatics 31
(1): 48-55.
1 January 2015
High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.
Ilm, K., Kemmner, W., Osterland, M., Burock, S., Koch, G., Herrmann, P., Schlag, P.M. and Stein, U.
Molecular Cancer 14
(1): 38.
14 February 2015
In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells.
Ito, H., Shiwaku, H., Yoshida, C., Homma, H., Luo, H., Chen, X., Fujita, K., Musante, L., Fischer, U., Frints, S.G.M., Romano, C., Ikeuchi, Y., Shimamura, T., Imoto, S., Miyano, S., Muramatsu, S.I., Kawauchi, T., Hoshino, M., Sudol, M., Arumughan, A., Wanker, E.E., Rich, T., Schwartz, C., Matsuzaki, F., Bonni, A., Kalscheuer, V.M. and Okazawa, H.
Molecular Psychiatry 20
(4): 459-471.
April 2015
Analysis of intron sequences reveals hallmarks of circular RNA biogenesis in animals.
Ivanov, A., Memczak, S., Wyler, E., Torti, F., Porath, H.T., Orejuela, M.R., Piechotta, M., Levanon, E.Y., Landthaler, M., Dieterich, C. and Rajewsky, N.
Cell Reports 10
(2): 170-177.
13 January 2015
Sleeping Beauty transposition.
Ivics, Z. and Izsvák, Z.
Microbiology Spectrum 3
(2)
April 2015
Sleeping Beauty transposition.
Ivics, Z. and Izsvák, Z.
In:
Mobile DNA III.
ASM Press, Washington, DC, 851-872.
ISBN 9781555819200
2015
Prevalence and characteristics of true and apparent treatment resistant hypertension in the Campania Salute Network.
Izzo, R., Stabile, E., Esposito, G., Trimarco, V., De Marco, M., Sica, A., Manzi, M.V., Gargiulo, G., Schiattarella, G., Rozza, F., De Luca, N. and de Simone, G.
International Journal of Cardiology 184
: 417-419.
1 April 2015
J
Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.
Jabir, M.S., Hopkins, L., Ritchie, N.D., Ullah, I., Bayes, H.K., Li, D., Tourlomousis, P., Lupton, A., Puleston, D., Simon, A.K., Bryant, C. and Evans, T.J.
Autophagy 11
(1): 166-182.
2015
Measurement of waist and hip circumference with a body surface scanner: feasibility, validity, reliability, and correlations with markers of the metabolic syndrome.
Jaeschke, L., Steinbrecher, A. and Pischon, T.
PLoS ONE 10
(3): e0119430.
6 March 2015
Does intensive multimodal treatment for maternal ADHD improve the efficacy of parent training for children with ADHD? A randomized controlled multicenter trial.
Jans, T., Jacob, C., Warnke, A., Zwanzger, U., Gross-Lesch, S., Matthies, S., Borel, P., Hennighausen, K., Haack-Dees, B., Roesler, M., Retz, W., von Gontard, A., Haenig, S., Sobanski, E., Alm, B., Poustka, L., Hohmann, S., Colla, M., Gentschow, L., Jaite, C., Kappel, V., Becker, K., Holtmann, M., Freitag, C., Graf, E., Ihorst, G. and Philipsen, A.
Journal of Child Psychology and Psychiatry 56
(12): 1298-1313.
December 2015
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.
Jansen, W.J., Ossenkoppele, R., Knol, D.L., Tijms, B.M., Scheltens, P., Verhey, F.R.J. and Visser, P.J.
JAMA: Journal of the American Medical Association 313
(19): 1924-1938.
19 May 2015
Treatment of chronic experimental autoimmune encephalomyelitis with epigallocatechin-3-gallate and glatiramer acetate alters expression of heme-oxygenase-1.
Janssen, A., Fiebiger, S., Bros, H., Hertwig, L., Romero-Suarez, S., Hamann, I., Chanvillard, C., Bellmann-Strobl, J., Paul, F., Millward, J.M. and Infante-Duarte, C.
PLoS ONE 10
(6): e0130251.
26 June 2015
Cutaneous Na(+) storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense.
Jantsch, J., Schatz, V., Friedrich, D., Schröder, A., Kopp, C., Siegert, I., Maronna, A., Wendelborn, D., Linz, P., Binger, K.J., Gebhardt, M., Heinig, M., Neubert, P., Fischer, F., Teufel, S., David, J.P., Neufert, C., Cavallaro, A., Rakova, N., Küper, C., Beck, F.X., Neuhofer, W., Muller, D.N., Schuler, G., Uder, M., Bogdan, C., Luft, F.C. and Titze, J.
Cell Metabolism 21
(3): 493-501.
3 March 2015
Competition between target sites of regulators shapes post-transcriptional gene regulation.
Jens, M. and Rajewsky, N.
Nature Reviews Genetics 16
(2): 113-126.
February 2015
Departure gate of acidic Ca(2+) confirmed.
Jentsch, T.J., Hoegg-Beiler, M.B. and Vogt, J.
EMBO Journal 34
(13): 1737-1739.
2 July 2015
Discovery of CLC transport proteins: cloning, structure, function and pathophysiology.
Jentsch, T.J.
Journal of Physiology 593
(18): 4091-4109.
15 September 2015
Neutrophil serine proteases exert proteolytic activity on endothelial cells.
Jerke, U., Perez Hernandez, D., Beaudette, P., Korkmaz, B., Dittmar, G. and Kettritz, R.
Kidney International 88
(4): 764-775.
October 2015
Eight-channel transceiver RF coil array tailored for (1)H/(19)F MR of the human knee and fluorinated drugs at 7.0 T.
Ji, Y., Waiczies, H., Winter, L., Neumanova, P., Hofmann, D., Rieger, J., Mekle, R., Waiczies, S. and Niendorf, T.
NMR in Biomedicine 28
(6): 726-737.
June 2015
Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1.
Jia, S., Wildner, H. and Birchmeier, C.
Developmental Biology 408
(1): 90-98.
1 December 2015
Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.
Jia, S., Ivanov, A., Blasevic, D., Müller, T., Purfürst, B., Sun, W., Chen, W., Poy, M.N., Rajewsky, N. and Birchmeier, C.
EMBO Journal 34
(10): 1417-1433.
12 May 2015
Ryanodine receptor activation induces long-term plasticity of spine calcium dynamics.
Johenning, F.W., Theis, A.K., Pannasch, U., Rückl, M., Rüdiger, S. and Schmitz, D.
PLoS Biology 13
(6): e1002181.
22 June 2015
Antiangiogenic and neurogenic activities of Sleeping Beauty-mediated PEDF-transfected RPE cells in vitro and in vivo.
Johnen, S., Djalali-Talab, Y., Kazanskaya, O., Möller, T., Harmening, N., Kropp, M., Izsvák, Z., Walter, P. and Thumann, G.
BioMed Research International 2015
: 863845.
2015
Gene repositioning within the cell nucleus is not random and is determined by its genomic neighborhood.
Jost, K.L., Bertulat, B., Rapp, A., Brero, A., Hardt, T., Domaing, P., Gösele, C., Schulz, H., Hübner, N. and Cardoso, M.C.
Epigenetics & Chromatin 8
: 36.
17 September 2015
In vivo monosynaptic excitatory transmission between layer 2 cortical pyramidal neurons.
Jouhanneau, J.S., Kremkow, J., Dorrn, A.L. and Poulet, J.F.A.
Cell Reports 13
(10): 2098-2106.
15 December 2015
Dynamic profiling of the protein life cycle in response to pathogens.
Jovanovic, M., Rooney, M.S., Mertins, P., Przybylski, D., Chevrier, N., Satija, R., Rodriguez, E.H., Fields, A.P., Schwartz, S., Raychowdhury, R., Mumbach, M.R., Eisenhaure, T., Rabani, M., Gennert, D., Lu, D., Delorey, T., Weissman, J.S., Carr, S.A., Hacohen, N. and Regev, A.
Science 347
(6226): 1259038.
6 March 2015
Palliative treatment of uncontrollable hypercalcemia due to parathyrotoxicosis: denosumab as rescue therapy.
Jumpertz von Schwartzenberg, R., Elbelt, U., Ventz, M., Mai, K., Kienitz, T., Maurer, L, Rose, T., Rueckert, J.C., Strasburger, C.J. and Spranger, J.
Endocrinology Diabetes and Metabolism Case Reports 2015
: 150082.
29 October 2015
Isolation of human colon stem cells using surface expression of PTK7.
Jung, P., Sommer, C., Barriga, F.M., Buczacki, S.J., Hernando-Momblona, X., Sevillano, M., Duran-Frigola, M., Aloy, P., Selbach, M., Winton, D.J. and Batlle, E.
Stem Cell Reports 5
(6): 979-987.
8 December 2015
Single-cell transcriptomics enters the age of mass production.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 58
(4): 563-564.
21 May 2015
Lineage fate of ductular reactions in liver injury and carcinogenesis.
Jörs, S., Jeliazkova, P., Ringelhan, M., Thalhammer, J., Dürl, S., Ferrer, J., Sander, M., Heikenwalder, M., Schmid, R.M., Siveke, J.T. and Geisler, F.
Journal of Clinical Investigation 125
(6): 2445-57.
1 June 2015
K
Differential expression of SHP-1 in chronic myeloid leukemia.
Kaeda, J., Neuman, D., Bonecker, S., Mills, K., Oberender, C., Amini, L., Ringel, F., Serra, A., Schwarz, M., Doerken, B., Zalcberg, I. and Le Coutre, P.
Leukemia & Lymphoma 56
(5): 1547-1549.
May 2015
Up-regulated MSI2 is associated with more aggressive chronic myeloid leukemia.
Kaeda, J., Ringel, F., Oberender, C., Mills, K., Quintarelli, C., Pane, F., Koschmieder, S., Slany, R., Schwarzer, R., Saglio, G., Hemmati, P., van Lessen, A., Amini, L., Greese, M., Vagge, E., Burmeister, T., Serra, A., Carson, A., Schwarz, M., Westermann, J., Jundt, F., Doerken, B. and le Coutre, P.
Leukemia & Lymphoma 56
(7): 2105-2113.
July 2015
Deformable meshes for medical image segmentation.
Kainmueller, D.
Aktuelle Forschung Medizintechnik - Latest Research in Medical Engineering
.
Springer Vieweg, Wiesbaden.
ISBN 978-3-658-07014-4
2015
Homozygous loss-of-function variants in european cosmopolitan and isolate populations.
Kaiser, V.B., Svinti, V., Prendergast, J.G., Chau, Y.Y., Campbell, A., Patarcic, I., Barroso, I., Joshi, P.K., Hastie, N.D., Miljkovic, A., Taylor, M.S., Enroth, S., Memari, Y., Kolb-Kokocinski, A., Wright, A.F., Gyllensten, U., Durbin, R., Rudan, I., Campbell, H., Polašek, O., Johansson, A., Sauer, S., Porteous, D.J., Fraser, R.M., Drake, C., Vitart, V., Hayward, C., Semple, C.A. and Wilson, J.F.
Human Molecular Genetics 24
(19): 5464-5474.
1 October 2015
STIL mutation causes autosomal recessive microcephalic lobar holoprosencephaly.
Kakar, N., Ahmad, J., Morris-Rosendahl, D.J., Altmüller, J., Friedrich, K., Barbi, G., Nürnberg, P., Kubisch, C., Dobyns, W.B. and Borck, G.
Human Genetics 134
(1): 45-51.
January 2015
Deep sequencing of the murine olfactory receptor neuron transcriptome.
Kanageswaran, N., Demond, M., Nagel, M., Schreiner, B.S.P., Baumgart, S., Scholz, P., Altmüller, J., Becker, C., Doerner, J.F., Conrad, H., Oberland, S., Wetzel, C.H., Neuhaus, E.M., Hatt, H. and Gisselmann, G.
PLoS ONE 10
(1): e0113170.
2015
Differential proteomic analysis of mouse macrophages exposed to adsorbate-loaded heavy fuel oil derived combustion particles using an automated sample-preparation workflow.
Kanashova, T., Popp, O., Orasche, J., Karg, E., Harndorf, H., Stengel, B., Sklorz, M., Streibel, T., Zimmermann, R. and Dittmar, G.
Analytical and Bioanalytical Chemistry 407
(20): 5965-5976.
August 2015
Exacerbation of acute kidney injury by bone marrow stromal cells from rats with persistent renin-angiotensin system activation.
Kankuri, E., Mervaala, E.E., Storvik, M., Ahola, A.M.J., Levijoki, J., Müller, D.N., Finckenberg, P. and Mervaala, E.M.
Clinical Science 128
(11): 735-747.
1 June 2015
Protein kinase Ymr291w/Tda1 is essential for glucose signaling in Saccharomyces cerevisiae on the level of hexokinase isoenzyme ScHxk2 phosphorylation.
Kaps, S., Kettner, K., Migotti, R., Kanashova, T., Krause, U., Roedel, G., Dittmar, G. and Kriegel, T.M.
Journal of Biological Chemistry 290
(10): 6243-6255.
6 March 2015
Effect of different omega-6/omega-3 polyunsaturated fatty acid ratios on the formation of monohydroxylated fatty acids in THP-1 derived macrophages.
Keeren, K., Huang, D., Smyl, C., Fischer, A., Rothe, M. and Weylandt, K.H.
Biology 4
(2): 314-326.
9 April 2015
Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis.
Keller, A., Leidinger, P., Meese, E., Haas, J., Backes, C., Rasche, L., Behrens, J.R., Pfuhl, C., Wakonig, K., Gieß, R.M., Jarius, S., Meder, B., Bellmann-Strobl, J., Paul, F., Pache, F.C. and Ruprecht, K.
Journal of Neuroinflammation 12
(1): 196.
31 October 2015
Multiplexed, quantitative workflow for sensitive biomarker discovery in plasma yields novel candidates for early myocardial injury.
Keshishian, H., Burgess, M.W., Gillette, M.A., Mertins, P., Clauser, K.R., Mani, D.R., Kuhn, E.W., Farrell, L.A., Gerszten, R.E. and Carr, S.A.
Molecular & Cellular Proteomics 14
(9): 2375-2393.
1 September 2015
In memoriam: Uwe-Karsten Hanisch (May 6, 1961 to April 18, 2015).
Kettenmann, H. and Prinz, M.
Glia 63
(8): 1285-1287.
August 2015
Iatrogene Elektrolytstoerungen [Iatrogenic Electrolyte Disorders].
Kettritz, R. and Luft, F.C.
Internist 56
(7): 745-752.
1 July 2015
Comparison of standard versus wide-field composite images of the corneal subbasal layer by In vivo confocal microscopy.
Kheirkhah, A., Muller, R., Mikolajczak, J., Ren, A., Kadas, E.M., Zimmermann, H., Pruess, H., Paul, F., Brandt, A.U. and Hamrah, P.
Investigative Ophthalmology & Visual Science 56
(10): 5801-5807.
1 September 2015
The effect of endothelialization on the epidermal differentiation in human three-dimensional skin constructs – A morphological study.
Khiao In, M., Wallmeyer, L., Hedtrich, S., Richardson, K.C., Plendl, J. and Kaessmeyer, S.
Clinical Hemorheology and Microcirculation 61
(2): 157-174.
2015
MRI characteristics of neuromyelitis optica spectrum disorder: An international update.
Kim, H.J., Paul, F., Lana-Peixoto, M.A., Tenembaum, S., Asgari, N., Palace, J., Klawiter, E.C., Sato, D.K., de Seze, J., Wuerfel, J., Banwell, B.L., Villoslada, P., Saiz, A., Fujihara, K. and Kim, S.H.
Neurology 84
(11): 1165-1173.
17 March 2015
Pushing the boundaries of neuromyelitis optica: Does antibody make the disease?
Kister, I. and Paul, F.
Neurology 85
(2): 118-119.
14 July 2015
Malformations of the left ventricle: what comes first: form or function?
Klaassen, S.
Circulation Cardiovascular Genetics 8
(4): 537-540.
August 2015
A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.
Klinghammer, K., Raguse, J.D., Plath, T., Albers, A.E., Joehrens, K., Zakarneh, A., Brzezicha, B., Wulf-Goldenberg, A., Keilholz, U., Hoffmann, J. and Fichtner, I.
International Journal of Cancer 136
(12): 2940-2948.
15 June 2015
On the subjective acceptance during cardiovascular magnetic resonance imaging at 7.0 Tesla.
Klix, S., Els, A., Paul, K., Graessl, A., Oezerdem, C., Weinberger, O., Winter, L., Thalhammer, C., Huelnhagen, T., Rieger, J., Mehling, H., Schulz-Menger, J. and Niendorf, T.
PLoS ONE 10
(1): e0117095.
26 January 2015
TET proteins and 5-methylcytosine oxidation in hematological cancers.
Ko, M., An, J., Pastor, W.A., Koralov, S.B., Rajewsky, K. and Rao, A.
Immunological Reviews 263
(1): 6-21.
January 2015
Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study.
Koelzer, V.H., Herrmann, P., Zlobec, I., Karamitopoulou, E., Lugli, A. and Stein, U.
BMC Cancer 15
(1): 160.
21 March 2015
4-fragment gateway cloning format for MosSCI-compatible vectors integrating promoterome and 3'UTRome libraries of Caenorhabditis elegans.
Kogame, T.
Journal of Medical Investigation 62
(3.4): 161-166.
18 September 2015
Vesicular synaptobrevin/VAMP2 levels guarded by AP180 control efficient neurotransmission.
Koo, S.J., Kochlamazashvili, G., Rost, B., Puchkov, D., Gimber, N., Lehmann, M., Tadeus, G., Schmoranzer, J., Rosenmund, C., Haucke, V. and Maritzen, T.
Neuron 88
(2): 330-344.
21 October 2015
The latent dementia phenotype δ is associated with cerebrospinal fluid biomarkers of Alzheimer's disease and predicts conversion to dementia in subjects with mild cognitive impairment.
Koppara, A., Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Froelich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F.M., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Pantel, J., Rienhoff, O., Ruether, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J. and Wagner, M.
Journal of Alzheimer's Disease 49
(2): 547-560.
17 October 2015
Targeted sequencing using a 47 gene multiple myeloma mutation panel (M(3) P) in -17p high risk disease.
Kortüm, K.M., Langer, C., Monge, J., Bruins, L., Egan, J.B., Zhu, Y.X., Shi, C.X., Jedlowski, P., Schmidt, J., Ojha, J., Bullinger, L., Liebisch, P., Kull, M., Champion, M.D., Van Wier, S., Ahmann, G., Rasche, L., Knop, S., Fonseca, R., Einsele, H., Stewart, A.K. and Braggio, E.
British Journal of Haematology 168
(4): 507-510.
February 2015
Longitudinal analysis of 25 sequential sample-pairs using a custom multiple myeloma mutation sequencing panel (M(3)P).
Kortüm, K.M., Langer, C., Monge, J., Bruins, L., Zhu, Y.X., Shi, C.X., Jedlowski, P., Egan, J.B., Ojha, J., Bullinger, L., Kull, M., Ahmann, G., Rasche, L., Knop, S., Fonseca, R., Einsele, H., Stewart, A.K. and Braggio, E.
Annals of Hematology 94
(7): 1205-1211.
July 2015
Signaling networks in MS: a systems-based approach to developing new pharmacological therapies.
Kotelnikova, E., Bernardo-Faura, M., Silberberg, G., Kiani, N.A., Messinis, D., Melas, I.N., Artigas, L., Schwartz, E., Mazo, I., Masso, M., Alexopoulos, L.G., Mas, J.M., Olsson, T., Tegner, J., Martin, R., Zamora, A., Paul, F., Saez-Rodriguez, J. and Villoslada, P.
Multiple Sclerosis Journal 21
(2): 138-146.
February 2015
New developments in the pathogenesis of obesity-induced hypertension.
Kotsis, V., Nilsson, P., Grassi, G., Mancia, G., Redon, J., Luft, F., Schmieder, R., Engeli, S., Stabouli, S., Antza, C., Pall, D., Schlaich, M. and Jordan, J.
Journal of Hypertension 33
(8): 1499-1508.
August 2015
An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex.
Kracker, S., Di Virgilio, M., Schwartzentruber, J., Cuenin, C., Forveille, M., Deau, M.C., McBride, K.M., Majewski, J., Gazumyan, A., Seneviratne, S., Grimbacher, B., Kutukculer, N., Herceg, Z., Cavazzana, M., Jabado, N., Nussenzweig, M.C., Fischer, A. and Durandy, A.
Journal of Allergy and Clinical Immunology 135
(4): 998-1007.
April 2015
Deletions, inversions, duplications: engineering of structural variants using CRISPR/Cas in mice.
Kraft, K., Geuer, S., Will, A.J., Chan, W.L., Paliou, C., Borschiwer, M., Harabula, I., Wittler, L., Franke, M., Ibrahim, D.M., Kragesteen, B.K., Spielmann, M., Mundlos, S., Lupiáñez, D.G. and Andrey, G.
Cell Reports 10
(5): 833-839.
10 February 2015
Hypertrophic Cardiomyopathy Registry: the rationale and design of an international, observational study of hypertrophic cardiomyopathy.
Kramer, C.M., Appelbaum, E., Desai, M.Y., Desvigne-Nickens, P., DiMarco, J.P., Friedrich, M.G., Geller, N., Heckler, S., Ho, C.Y., Jerosch-Herold, M., Ivey, E.A., Keleti, J., Kim, D.Y., Kolm, P., Kwong, R.Y., Maron, M.S., Schulz-Menger, J., Piechnik, S., Watkins, H., Weintraub, W.S., Wu, P. and Neubauer, S.
American Heart Journal 170
(2): 223-230.
August 2015
KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth.
Kravtsova-Ivantsiv, Y., Shomer, I., Cohen-Kaplan, V., Snijder, B., Superti-Furga, G., Gonen, H., Sommer, T., Ziv, T., Admon, A., Naroditsky, I., Jbara, M., Brik, A., Pikarsky, E., Kwon, Y.T., Doweck, I. and Ciechanover, A.
Cell 161
(2): 333-347.
9 April 2015
Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: its more than NF-κB!
Kreher, S., Cauchy, P., Bonifer, C. and Mathas, S.
Cytokine 72
(1): 115-117.
March 2015
Use of advanced magnetic resonance imaging techniques in neuromyelitis optica spectrum disorder.
Kremer, S., Renard, F., Achard, S., Lana-Peixoto, M.A., Palace, J., Asgari, N., Klawiter, E.C., Tenembaum, S.N., Banwell, B., Greenberg, B.M., Bennett, J.L., Levy, M., Villoslada, P., Saiz, A., Fujihara, K., Chan, K.H., Schippling, S., Paul, F., Kim, H.J., de Seze, J. and Wuerfel, J.T.
JAMA Neurology 72
(7): 815-822.
July 2015
The prognostic impact of CD163-positive macrophages in follicular lymphoma: a study from the BC Cancer Agency and the Lymphoma Study Association.
Kridel, R., Xerri, L., Gelas-Dore, B., Tan, K., Feugier, P., Vawda, A., Canioni, D., Farinha, P., Boussetta, S., Moccia, A.A., Brice, P., Chavez, E.A., Kyle, A.H., Scott, D.W., Sanders, A.D., Fabiani, B., Slack, G.W., Minchinton, A.I., Haioun, C., Connors, J.M., Sehn, L.H., Steidl, C., Gascoyne, R.D. and Salles, G.
Clinical Cancer Research 21
(15): 3428-3435.
August 2015
Very late-onset neuromyelitis optica spectrum disorder beyond the age of 75.
Krumbholz, M., Hofstadt-van Oy, U., Angstwurm, K., Kleiter, I., Jarius, S., Paul, F., Aktas, O., Buchholz, G., Kern, P., Straube, A. and Kümpfel, T.
Journal of Neurology 262
(5): 1379-1384.
May 2015
Yersinia enterocolitica type III secretion injectisomes form regularly spaced clusters, which incorporate new machines upon activation.
Kudryashev, M., Diepold, A., Amstutz, M., Armitage, J.P., Stahlberg, H. and Cornelis, G.R.
Molecular Microbiology 95
(5): 875-884.
March 2015
Structure of the type VI secretion system contractile sheath.
Kudryashev, M., Wang, R.Y.R., Brackmann, M., Scherer, S., Maier, T., Baker, D., DiMaio, F., Stahlberg, H., Egelman, E.H. and Basler, M.
Cell 160
(5): 952-962.
26 February 2015
Exome sequencing identifies a novel heterozygous TGFB3 mutation in a disorder overlapping with Marfan and Loeys-Dietz syndrome.
Kuechler, A., Altmüller, J., Nürnberg, P., Kotthoff, S., Kubisch, C. and Borck, G.
Molecular and Cellular Probes 29
(5): 330-334.
October 2015
Hair cortisol and cortisol awakening response are associated with criteria of the metabolic syndrome in opposite directions.
Kuehl, L.K., Hinkelmann, K., Muhtz, C., Dettenborn, L., Wingenfeld, K., Spitzer, C., Kirschbaum, C., Wiedemann, K. and Otte, C.
Psychoneuroendocrinology 51
: 365-370.
January 2015
Maui-VIA: a user-friendly software for visual identification, alignment, correction, and quantification of gas chromatography-mass spectrometry data.
Kuich, P.H.J.L., Hoffmann, N. and Kempa, S.
Frontiers in Bioengineering and Biotechnology 2
: 84.
21 January 2015
Iridodonesis as a cause of recurrent vertigo.
Kunte, H., Paul, F., Pache, F., Doerr, J., Bellmann-Strobl, J., Harms, L. and Kronenberg, G.
Neurology 85
(15): 1353.
13 October 2015
Mitochondrial networks in cardiac myocytes reveal dynamic coupling behavior.
Kurz, F.T., Derungs, T., Aon, M.A., O'Rourke, B. and Armoundas, A.A.
Biophysical Journal 108
(8): 1922-1933.
21 April 2015
17β-estradiol regulates mTORC2 sensitivity to rapamycin in adaptive cardiac remodeling.
Kusch, A., Schmidt, M., Gürgen, D., Postpieszala, D., Catar, R., Hegner, B., Davidson, M.M., Mahmoodzadeh, S. and Dragun, D.
PLoS ONE 10
(4): e0123385.
16 April 2015
Implementation of amplicon parallel sequencing leads to improvement of diagnosis and therapy of lung cancer patients.
König, K., Peifer, M., Fassunke, J., Ihle, M.A., Künstlinger, H., Heydt, C., Stamm, K., Ueckeroth, F., Vollbrecht, C., Bos, M., Gardizi, M., Scheffler, M., Nogova, L., Leenders, F., Albus, K., Meder, L., Becker, K., Florin, A., Rommerscheidt-Fuss, U., Altmüller, J., Kloth, M., Nürnberg, P., Henkel, T., Bikár, S.E., Sos, M.L., Geese, W.J., Strauss, L., Ko, Y.D., Gerigk, U., Odenthal, M., Zander, T., Wolf, J., Merkelbach-Bruse, S., Buettner, R. and Heukamp, L.C.
Journal of Thoracic Oncology 10
(7): 1049-1057.
July 2015
Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9.
Kühn, R. and Chu, V.T.
Genome Biology 16
(1): 244.
10 November 2015
LARP4B is an AU-rich sequence associated factor that promotes mRNA accumulation and translation.
Küspert, M., Murakawa, Y., Schäffler, K., Vanselow, J.T., Wolf, E., Juranek, S., Schlosser, A., Landthaler, M. and Fischer, U.
RNA 21
(7): 1294-1305.
July 2015
L
Immuntherapie von Kopf-Hals-Karzinomen - Highlights des ASCO-Kongresses 2015 [Immunotherapy of head and neck tumors: Highlights of the ASCO Meeting 2015].
Laban, S., Doescher, J., Schuler, P.J., Bullinger, L., Brunner, C., Veit, J.A. and Hoffmann, T.K.
HNO 63
(9): 612-619.
September 2015
How cell death shapes cancer.
Labi, V. and Erlacher, M.
Cell Death & Disease 6
: e1675.
5 March 2015
Cross-tissue and cross-species analysis of gene expression in skeletal muscle and electric organ of African weakly-electric fish (Teleostei; Mormyridae).
Lamanna, F., Kirschbaum, F., Waurick, I., Dieterich, C. and Tiedemann, R.
BMC Genomics 16
(1): 668.
3 September 2015
Interaction of epoxyeicosatrienoic acids and adipocyte fatty acid-binding protein in the modulation of cardiomyocyte contractility.
Lamounier-Zepter, V., Look, C., Schunck, W.H., Schlottmann, I., Woischwill, C., Bornstein, S.R., Xu, A. and Morano, I.
International Journal of Obesity 39
(5): 755-761.
May 2015
Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.
Lan, L., Holland, J.D., Qi, J., Grosskopf, S., Rademann, J., Vogel, R., Gyoerffy, B., Wulf-Goldenberg, A. and Birchmeier, W.
EMBO Journal 34
(11): 1493-1508.
3 June 2015
Keeping those telomeres short! an innovative intratumoral long-term drug delivery system.
Laster, B.H., Isaacson, C., Perets, E., Msamra, M., Priel, E., Kalef-Ezra, J. and Kost, J.
Journal of Cancer Research and Clinical Oncology 141
(1): 23-34.
January 2015
Metastasis-associated in colon cancer 1 is an independent prognostic biomarker for survival in klatskin tumor patients.
Lederer, A., Herrmann, P., Seehofer, D., Dietel, M., Pratschke, J., Schlag, P. and Stein, U.
Hepatology 62
(3): 841-850.
September 2015
Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.
Lefebvre, J., Clarkson, M., Massa, F., Bradford, S.T., Charlet, A., Buske, F., Lacas-Gervais, S., Schulz, H., Gimpel, C., Hata, Y., Schaefer, F. and Schedl, A.
Kidney International 88
(2): 321-331.
August 2015
Human CD45RA(-) FoxP3(hi) memory-type regulatory T cells show distinct TCR repertoires with conventional T cells and play an important role in controlling early immune activation.
Lei, H., Kuchenbecker, L., Streitz, M., Sawitzki, B., Vogt, K., Landwehr-Kenzel, S., Millward, J., Juelke, K., Babel, N., Neumann, A., Reinke, P. and Volk, H.D.
American Journal of Transplantation 15
(10): 2625-2635.
October 2015
Cold-aggravated pain in humans caused by a hyperactive Na(V)1.9 channel mutant.
Leipold, E., Hanson-Kahn, A., Frick, M., Gong, P., Bernstein, J.A., Voigt, M., Katona, I., Oliver Goral, R., Altmüller, J., Nürnberg, P., Weis, J., Hübner, C.A., Heinemann, S.H. and Kurth, I.
Nature Communications 6
: 10049.
8 December 2015
Designer T cells - New possibilities for immunotherapy of cancer [Designer-T-Zellen - neue Möglichkeiten für die Immuntherapie von Krebs].
Leisegang, M. and Uckert, W.
BIOspektrum 21
(4): 402-405.
June 2015
Impact of prior treatment on outcome of transformed follicular lymphoma and relapsed de novo diffuse large B cell lymphoma: a retrospective multicentre analysis.
Lerch, K., Meyer, A.H., Stroux, A., Hirt, C., Keller, U., Viardot, A., Marks, R., Schreiber, S., Pezzutto, A. and Scholz, C.W.
Annals of Hematology 94
(6): 981-988.
June 2015
Agreement between 24-hour salt ingestion and sodium excretion in a controlled environment.
Lerchl, K., Rakova, N., Dahlmann, A., Rauh, M., Goller, U., Basner, M., Dinges, D.F., Beck, L., Agureev, A., Larina, I., Baranov, V., Morukov, B., Eckardt, K.U., Vassilieva, G., Wabel, P., Vienken, J., Kirsch, K., Johannes, B., Krannich, A., Luft, F.C. and Titze, J.
Hypertension 66
(4): 850-857.
October 2015
Increased apoptosis, altered oxygen signaling, and antioxidant defenses in first-trimester pregnancies with high-resistance uterine artery blood flow.
Leslie, K., Whitley, G.S.J., Herse, F., Dechend, R., Ashton, S.V., Laing, K., Thilaganathan, B. and Cartwright, J.E.
American Journal of Pathology 185
(10): 2731-2741.
October 2015
Validation of the Erlangen score algorithm for the prediction of the development of dementia due to Alzheimer's disease in pre-dementia subjects.
Lewczuk, P., Kornhuber, J., Toledo, J.B., Trojanowski, J.Q., Knapik-Czajka, M., Peters, O., Wiltfang, J. and Shaw, L.M.
Journal of Alzheimer's Disease 48
(2): 433-441.
9 September 2015
Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo.
Lim, H.W., Uhlenhaut, N.H., Rauch, A., Weiner, J., Hübner, S., Hübner, N., Won, K.J., Lazar, M.A., Tuckermann, J. and Steger, D.J.
Genome Research 25
(6): 836-844.
June 2015
Determinants of community structure in the global plankton interactome.
Lima-Mendez, G., Faust, K., Henry, N., Decelle, J., Colin, S., Carcillo, F., Chaffron, S., Ignacio-Espinosa, J.C., Roux, S., Vincent, F., Bittner, L., Darzi, Y., Wang, J., Audic, S., Berline, L., Bontempi, G., Cabello, A.M., Coppola, L., Cornejo-Castillo, F.M., d' Ovidio, F., De Meester, L., Ferrera, I., Garet-Delmas, M.J., Guidi, L., Lara, E., Pesant, S., Royo-Llonch, M., Salazar, G., Sanchez, P., Sebastian, M., Souffreau, C., Dimier, C., Picheral, M., Searson, S., Kandels-Lewis, S., Gorsky, G., Not, F., Ogata, H., Speich, S., Stemmann, L., Weissenbach, J., Wincker, P., Acinas, S.G., Sunagawa, S., Bork, P., Sullivan, M.B., Karsenti, E., Bowler, C., de Vargas, C. and Raes, J.
Science 348
(6237): 1262073.
22 May 2015
Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response.
Lindblom, R.P.F., Berg, A., Ström, M., Aeinehband, S., Dominguez, C.A., Al Nimer, F., Abdelmagid, N., Heinig, M., Zelano, J., Harnesk, K., Hübner, N., Nilsson, B., Ekdahl, K.N., Diez, M., Cullheim, S. and Piehl, F.
Journal of Neuroinflammation 12
: 192.
26 October 2015
Anatomic and pathological characterization of choroidal melanoma using multimodal imaging: what is practical, what is needed?
Lindner, T., Langner, S., Falke, K., Walter, U., Krueger, P.C., Pohlmann, A., Zimpfer, A., Stahnke, T., Hadlich, S., Guthoff, R., Erbersdobler, A., Niendorf, T. and Stachs, O.
Melanoma Research 25
(3): 252-258.
25 June 2015
Diffusionsgewichtete Magnetresonanztomografie und ihre potenziellen Anwendungsmoeglichkeiten in der Ophthalmologie [Diffusion weighted magnetic resonance imaging and its application in ophthalmology].
Lindner, T., Langner, S., Paul, K., Pohlmann, A., Hadlich, S., Niendorf, T., Jünemann, A., Guthoff, R.F. and Stachs, O.
Klinische Monatsblaetter fuer Augenheilkunde 232
(12): 1386-1391.
December 2015
Current questions and possible controversies in autophagy.
Lindqvist, L.M., Simon, A.K. and Baehrecke, E.H.
Cell Death Discovery 1
: 15036.
9 November 2015
Skin sodium measured with (23)Na MRI at 7.0 T.
Linz, P., Santoro, D., Renz, W., Rieger, J., Ruehle, A., Ruff, J., Deimling, M., Rakova, N., Muller, D.N., Luft, F.C., Titze, J. and Niendorf, T.
NMR in Biomedicine 28
(1): 54-62.
January 2015
Progression of kidney injury and cardiac remodeling in obese spontaneously hypertensive rats: the role of renal sympathetic innervation.
Linz, D., Hohl, M., Schuetze, J., Mahfoud, F., Speer, T., Linz, B., Hübschle, T., Juretschke, H.P., Dechend, R., Geisel, J., Rütten, H. and Böhm, M.
American Journal of Hypertension 28
(2): 256-265.
February 2015
Computational and statistical issues in personalized medicine.
Lippert, C. and Hackerman, D.
XRDS: Crossroads, The ACM Magazine for Students 21
(4): 24-27.
27 July 2015
Stable maintenance of de novo assembled human artificial chromosomes in embryonic stem cells and their differentiated progeny in mice.
Liskovykh, M., Ponomartsev, S., Popova, E., Bader, M., Kouprina, N., Larionov, V., Alenina, N. and Tomilin, A.
Cell Cycle 14
(8): 1268-1273.
15 April 2015
Deep sequencing of the trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients.
Llewellyn, M.S., Messenger, L.A., Luquetti, A.O., Garcia, L., Torrico, F., Tavares, S.B.N., Cheaib, B., Derome, N., Delepine, M., Baulard, C., Deleuze, J.F., Sauer, S. and Miles, M.A.
PLoS Neglected Tropical Diseases 9
(4): e0003458.
7 April 2015
Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium.
Lluch-Senar, M., Delgado, J., Chen, W.-H., Llorens-Rico, V., O'Reilly, F.J., Wodke, J.A.H., Unal, E.B., Yus, E., Martinez, S., Nichols, R.J., Ferrar, T., Vivancos, A., Schmeisky, A., Stuelke, J., van Noort, V., Gavin, A.-C., Bork, P. and Serrano, L.
Molecular Systems Biology 11
(1): 780.
21 January 2015
Large-scale zebrafish embryonic heart dissection for transcriptional analysis.
Lombardo, V.A., Otten, C. and Abdelilah-Seyfried, S.
Journal of Visualized Experiments
(95)
12 January 2015
Codon optimization of the human papillomavirus E7 oncogene induces a CD8(+) T cell response to a cryptic epitope not harbored by wild-type E7.
Lorenz, F.K.M., Wilde, S., Voigt, K., Kieback, E., Mosetter, B., Schendel, D.J. and Uckert, W.
PLoS ONE 10
(3): e0121633.
23 March 2015
The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease.
Louwersheimer, E., Ramirez, A., Cruchaga, C., Becker, T., Kornhuber, J., Peters, O., Heilmann, S., Wiltfang, J., Jessen, F., Visser, P.J., Scheltens, P., Pijnenburg, Y.A.L., Teunissen, C.E., Barkhof, F., van Swieten, J.C., Holstege, H. and van der Flier, W.M.
Neurobiology of Aging 36
(3): 1605.e13-1605.e20.
March 2015
Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
Ludwig, L.S., Cho, H., Wakabayashi, A., Eng, J.C., Ulirsch, J.C., Fleming, M.D., Lodish, H.F. and Sankaran, V.G.
American Journal of Hematology 90
(5): 386-91.
May 2015
Tripping out on TRPV4.
Luft, F.C.
Journal of Molecular Medicine 93
(12): 1283-1285.
December 2015
Mutant Cullin causes cardiovascular compromise.
Luft, F.C.
EMBO Molecular Medicine 7
(10): 1254-1256.
1 October 2015
Systematic medicine: strict rules [Systemmedizin: Strikte Regeln].
Luft, F.C.
Deutsches Aerzteblatt 112
(38): A1525-A1526.
18 September 2015
Osteoarthritis is what the people have.
Luft, F.C.
Journal of Molecular Medicine 93
(8): 819-821.
August 2015
Targeting epithelial-mesenchymal transition.
Luft, F.C.
Journal of Molecular Medicine 93
(7): 703-705.
1 July 2015
Fitting homocysteine to disease models, as well as adjusting the models to the disease.
Luft, F.C.
Journal of Molecular Medicine 93
(6): 585-587.
June 2015
Personalizing precision medicine.
Luft, F.C.
Journal of the American Society of Hypertension 9
(6): 415-416.
June 2015
Blood and iron.
Luft, F.C.
Journal of Molecular Medicine 93
(5): 469-471.
May 2015
Aortic stenosis is largely a boney affair.
Luft, F.C.
Journal of Molecular Medicine 93
(4): 357-359.
1 April 2015
Approaching the Hayflick limit.
Luft, F.C.
Trends in Cardiovascular Medicine 25
(3): 240-242.
April 2015
Clinical salt deficits.
Luft, F.C.
Pfluegers Archiv European Journal of Physiology 467
(3): 559-563.
March 2015
Resistente Hypertonie : Was ist das? [Resistant hypertension : What is it?].
Luft, F.C.
Internist 56
(3): 224-229.
March 2015
C/EBPβ LIP induces a tumor menagerie making it an oncogene.
Luft, F.C.
Journal of Molecular Medicine 93
(1): 1-3.
January 2015
Neuroforum und e-Neuroforum - der naechste Schritt [Neuroforum and e-Neuroforum - the next step].
Luhmann, H.J. and Kettenmann, H.
Neuroforum 21
(1): 1.
March 2015
Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions.
Lupiáñez, D.G., Kraft, K., Heinrich, V., Krawitz, P., Brancati, F., Klopocki, E., Horn, D., Kayserili, H., Opitz, J.M., Laxova, R., Santos-Simarro, F., Gilbert-Dussardier, B., Wittler, L., Borschiwer, M., Haas, S.A., Osterwalder, M., Franke, M., Timmermann, B., Hecht, J., Spielmann, M., Visel, A. and Mundlos, S.
Cell 161
(5): 1012-1025.
21 May 2015
M
PDE3A mutations cause autosomal dominant hypertension with brachydactyly.
Maass, P.G., Aydin, A., Luft, F.C., Schächterle, C., Weise, A., Stricker, S., Lindschau, C., Vaegler, M., Qadri, F., Toka, H.R., Schulz, H., Krawitz, P.M., Parkhomchuk, D., Hecht, J., Hollfinger, I., Wefeld-Neuenfeld, Y., Bartels-Klein, E., Mühl, A., Kann, M., Schuster, H., Chitayat, D., Bialer, M.G., Wienker, T.F., Ott, J., Rittscher, K., Liehr, T., Jordan, J., Plessis, G., Tank, J., Mai, K., Naraghi, R., Hodge, R., Hopp, M., Hattenbach, L.O., Busjahn, A., Rauch, A., Vandeput, F., Gong, M., Rüschendorf, F., Hübner, N., Haller, H., Mundlos, S., Bilginturan, N., Movsesian, M.A., Klussmann, E., Toka, O. and Bähring, S.
Nature Genetics 47
(6): 647-653.
June 2015
Alternatives Spleißen im Herzen [Alternative splicing in the heart].
Maatz, H., Heinig, M. and Hübner, N.
BIOspektrum 21
(1): 53-56.
February 2015
Extensive identification and analysis of conserved small ORFs in animals.
Mackowiak, S.D., Zauber, H., Bielow, C., Thiel, D., Kutz, K., Calviello, L., Mastrobuoni, G., Rajewsky, N., Kempa, S., Selbach, M. and Obermayer, B.
Genome Biology 16
: 179.
14 September 2015
Ultrahigh-field MPRAGE magnetic resonance angiography at 7.0 T in patients with cerebrovascular disease.
Madai, V.I., von Samson-Himmelstjerna, F.C., Sandow, N., Weiler, F., Bauer, M., Vajkoczy, P., Günther, M., Dusek, P., von Gottberg, P., Niendorf, T., Wuerfel, J. and Sobesky, J.
European Journal of Radiology 84
(12): 2613-2617.
December 2015
Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states.
Madalli, S., Beyrau, M., Whiteford, J., Duchene, J., Singh Nandhra, I., Patel, N.S.A., Motwani, M.P., Gilroy, D.W., Thiemermann, C., Nourshargh, S. and Scotland, R.S.
Biology of Sex Differences 6
: 27.
26 November 2015
Histopathology in 3D: from three-dimensional reconstruction to multi-stain and multi-modal analysis.
Magee, D., Song, Y., Gilbert, S., Roberts, N., Wijayathunga, N., Wilcox, R., Bulpitt, A. and Treanor, D.
Journal of Pathology Informatics 6
: 6.
24 February 2015
Functional proteomic analysis of repressive histone methyltransferase complexes reveals ZNF518B as a G9A regulator.
Maier, V.K., Feeney, C.M., Taylor, J.E., Creech, A.L., Qiao, J.W., Szanto, A., Das, P.P., Chevrier, N., Cifuentes-Rojas, C., Orkin, S.H., Carr, S.A., Jaffe, J.D., Mertins, P. and Lee, J.T.
Molecular & Cellular Proteomics 14
(6): 1435-1446.
1 June 2015
Finding sparse features in strongly confounded
medical binary data.
Mandt, S., Wenzel, F., Nakajima, S., Cunningham, J., Lippert, C. and Kloft, M.
In: NIPS Workshop on Machine Learning in Healthcare.
2015
Disassembly of Lys11- and mixed-linkage polyubiquitin conjugates provide insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.
Mansour, W., Nakasone, M.A., von Delbrück, M., Yu, Z., Krutauz, D., Reis, N., Kleifeld, O., Sommer, T., Fushman, D. and Glickman, M.H.
Journal of Biological Chemistry 290
(8): 4688-4704.
20 February 2015
The genetics of the skin barrier in eczema and other allergic disorders.
Marenholz, I., Esparza-Gordillo, J. and Lee, Y.A.
Current Opinion in Allergy and Clinical Immunology 15
(5): 426-434.
October 2015
Meta-analysis identifies seven susceptibility loci involved in the atopic march.
Marenholz, I., Esparza-Gordillo, J., Rüschendorf, F., Bauerfeind, A., Strachan, D.P., Spycher, B.D., Baurecht, H., Margaritte-Jeannin, P., Sääf, A., Kerkhof, M., Ege, M., Baltic, S., Matheson, M.C., Li, J., Michel, S., Ang, W.Q., McArdle, W., Arnold, A., Homuth, G., Demenais, F., Bouzigon, E., Söderhäll, C., Pershagen, G., de Jongste, J.C., Postma, D.S., Braun-Fahrlaender, C., Horak, E., Ogorodova, L.M., Puzyrev, V.P., Bragina, E.Y., Hudson, T.J., Morin, C., Duffy, D.L., Marks, G.B., Robertson, C.F., Montgomery, G.W., Musk, B., Thompson, P.J., Martin, N.G., James, A., Sleiman, P., Toskala, E., Rodriguez, E., Fölster-Holst, R., Franke, A., Lieb, W., Gieger, C., Heinzmann, A., Rietschel, E., Keil, T., Cichon, S., Nöthen, M.M., Pennell, C.E., Sly, P.D., Schmidt, C.O., Matanovic, A., Schneider, V., Heinig, M., Hübner, N., Holt, P.G., Lau, S., Kabesch, M., Weidinger, S., Hakonarson, H., Ferreira, M.A.R., Laprise, C., Freidin, M.B., Genuneit, J., Koppelman, G.H., Melén, E., Dizier, M.H., Henderson, A.J. and Lee, Y.A.
Nature Communications 6
: 8804.
6 November 2015
Lrp1/LDL receptor play critical roles in mannose 6-phosphate-independent lysosomal enzyme targeting.
Markmann, S., Thelen, M., Cornils, K., Schweizer, M., Brocke-Ahmadinejad, N., Willnow, T., Heeren, J., Gieselmann, V., Braulke, T. and Kollmann, K.
Traffic 16
(7): 743-759.
July 2015
Principles of protein targeting to the nucleolus.
Martin, R.M., Ter-Avetisyan, G., Herce, H.D., Ludwig, A.K., Lättig-Tünnemann, G. and Cardoso, M.C.
Nucleus 6
(4): 314-325.
17 August 2015
Frequent induction of chromosomal aberrations in in vivo skin fibroblasts after allogeneic stem cell transplantation: hints to chromosomal instability after irradiation.
Massenkeil, G., Zschieschang, P., Thiel, G., Hemmati, P.G., Budach, V., Doerken, B., Pross, J. and Arnold, R.
Radiation Oncology 10
: 266.
30 December 2015
Brain in flames - animal models of psychosis: utility and limitations.
Mattei, D., Schweibold, R. and Wolf, S.A.
Neuropsychiatric Disease and Treatment 11
: 1313-1329.
27 May 2015
Genome-wide identification and characterisation of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing.
Mazloomian, A. and Meyer, I.M.
RNA Biology 12
(12): 1391-1401.
December 2015
RAGE mediates the pro-migratory response of extracellular S100A4 in human thyroid cancer cells.
Medapati, M.R., Dahlmann, M., Ghavami, S., Pathak, K.A., Lucman, L., Klonisch, T., Hoang-Vu, C., Stein, U. and Hombach-Klonisch, S.
Thyroid 25
(5): 514-527.
4 May 2015
The interplay of Hrd3 and the molecular chaperone system ensures efficient degradation of malfolded secretory proteins.
Mehnert, M., Sommermeyer, F., Berger, M., Lakshmipathy, S.K., Gauss, R., Aebi, M., Jarosch, E. and Sommer, T.
Molecular Biology of the Cell 26
(2): 185-194.
15 January 2015
Structure-activity relationship study of dendritic polyglycerolamines for efficient siRNA transfection.
Mehrabadi, F.S., Hirsch, O., Zeisig, R., Posocco, P., Laurini, E., Pricl, S., Haag, R., Kemmner, W. and Calderon, M.
RSC Advances 5
(96): 78760-78770.
8 September 2015
Update on biomarkers in neuromyelitis optica.
Melamed, E., Levy, M., Waters, P.J., Sato, D.K., Bennett, J.L., John, G.R., Hooper, D.C., Saiz, A., Bar-Or, A., Kim, H.J., Pandit, L., Leite, M.I., Asgari, N., Kissani, N., Hintzen, R., Marignier, R., Jarius, S., Marcelletti, J., Smith, T.J., Yeaman, M.R. and Han, M.H.
Neurology Neuroimmunology & Neuroinflammation 2
(4): e134.
23 July 2015
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood.
Memczak, S., Papavasileiou, P., Peters, O. and Rajewsky, N.
PLoS ONE 10
(10): e0141214.
20 October 2015
Altered B-cell subsets and functional B-cell defects in selective IgM deficiency.
Mensen, A., Krause, T., Hanitsch, L.G., Meisel, C., Kleint, M.E., Volk, H.D., Na, I.K. and Scheibenbogen, C.
Clinical Immunology 161
(2): 96-102.
December 2015
Apoptosis-susceptibility prolongs the lack of memory B cells in acute leukemic patients after allogeneic hematopoietic stem cell transplantation.
Mensen, A., Oh, Y., Becker, S.C., Hemmati, P.G., Jehn, C., Westermann, J., Szyska, M., Göldner, H., Dörken, B., Scheibenbogen, C., Arnold, R. and Na, I.K.
Biology of Blood and Marrow Transplantation 21
(11): 1895-1906.
November 2015
Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism.
Menzfeld, C., John, M., van Rossum, D., Regen, T., Scheffel, J., Janova, H., Götz, A., Ribes, S., Nau, R., Borisch, A., Boutin, P., Neumann, K., Bremes, V., Wienands, J., Reichardt, H.M., Lühder, F., Tischner, D., Waetzig, V., Herdegen, T., Teismann, P., Greig, I., Müller, M., Pukrop, T., Mildner, A., Kettenmann, H., Brück, W., Prinz, M., Rotshenker, S., Weber, M.S. and Hanisch, U.K.
Glia 63
(6): 1083-1099.
June 2015
Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis.
Merzaban, J.S., Imitola, J., Starossom, S.C., Zhu, B., Wang, Y., Lee, J., Ali, A.J., Olah, M., Abuelela, A.F., Khoury, S.J. and Sackstein, R.
Glycobiology 25
(12): 1392–1409.
December 2015
Acyclovir has low but detectable influence on HLA-B*57:01 specificity without inducing hypersensitivity.
Metushi, I.G., Wriston, A., Banerjee, P., Gohlke, B.O., English, A.M., Lucas, A., Moore, C., Sidney, J., Buus, S., Ostrov, D.A., Mallal, S., Phillips, E., Shabanowitz, J., Hunt, D.F., Preissner, R. and Peters, B.
PLoS ONE 10
(5): e0124878.
29 May 2015
Quantitative affinity purification mass spectrometry: a versatile technology to study protein-protein interactions.
Meyer, K. and Selbach, M.
Frontiers in Genetics 6
: 237.
July 2015
Tissue structure and inflammatory processes shape viscoelastic properties of the mouse brain.
Millward, J.M., Guo, J., Berndt, D., Braun, J., Sack, I. and Infante-Duarte, C.
NMR in Biomedicine 28
(7): 831-839.
July 2015
PTMcode v2: a resource for functional associations of post-translational modifications within and between proteins.
Minguez, P., Letunic, I., Parca, L., Garcia-Alonso, L., Dopazo, J., Huerta-Cepas, J. and Bork, P.
Nucleic Acids Research 43
(Database issue): D494-D502.
28 January 2015
Regnase-1 and roquin regulate a common element in inflammatory mRNAs by spatiotemporally distinct mechanisms.
Mino, T., Murakawa, Y., Fukao, A., Vandenbon, A., Wessels, H.H., Ori, D., Uehata, T., Tartey, S., Akira, S., Suzuki, Y., Vinuesa, C.G., Ohler, U., Standley, D.M., Landthaler, M., Fujiwara, T. and Takeuchi, O.
Cell 161
(5): 1058-1073.
21 May 2015
Noncorticosteroid immunosuppression limits myocardial damage and contractile dysfunction in eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome).
Miszalski-Jamka, T., Szczeklik, W., Sokolowska, B., Karwat, K., Miszalski-Jamka, K., Jazwiec, P., Malek, L.A., Al-Khalidi, H., Schulz-Menger, J., Mavrogeni, S., Mahr, A., Mazur, W., Kereiakes, D.J. and Musial, J.
Journal of the American College of Cardiology 65
(1): 103-105.
6 January 2015
Functional, morphological, and apoptotic alterations in skeletal muscle of ARC deficient mice.
Mitchell, A.S., Smith, I.C., Gamu, D., Donath, S., Tupling, A.R. and Quadrilatero, J.
Apoptosis 20
(3): 310-326.
March 2015
The Src Homology and Collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.
Mlih, M., Host, L., Martin, S., Niederhoffer, N., Monassier, L., Terrand, J., Messaddeq, N., Radke, M., Gotthardt, M., Bruban, V., Kober, F., Bernard, M., Canet-Soulas, E., Abt-Jijon, F., Boucher, P. and Matz, R.L.
Journal of Biological Chemistry 290
(4): 2419-2430.
23 January 2015
Decoding the regulatory network of early blood development from single-cell gene expression measurements.
Moignard, V., Woodhouse, S., Haghverdi, L., Lilly, A.J., Tanaka, Y., Wilkinson, A.C., Buettner, F., Macaulay, I.C., Jawaid, W., Diamanti, E., Nishikawa, S.I., Piterman, N., Kouskoff, V., Theis, F.J., Fisher, J. and Göttgens, B.
Nature Biotechnology 33
(3): 269-276.
March 2015
Monocytes compensate Kupffer cell loss during bacterial infection.
Molawi, K. and Sieweke, M.H.
Immunity 42
(1): 10-12.
20 January 2015
Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Momeny, M., Saunus, J.M., Marturana, F., McCart Reed, A.E., Black, D., Sala, G., Iacobelli, S., Holland, J.D., Yu, D., Da Silva, L., Simpson, P.T., Khanna, K.K., Chenevix-Trench, G. and Lakhani, S.R.
Oncotarget 6
(6): 3932-3946.
19 February 2015
Cellular origin of prognostic chromosomal aberrations in AML patients.
Mora-Jensen, H., Jendholm, J., Rapin, N., Andersen, M.K., Roug, A.S., Bagger, F.O., Bullinger, L., Winther, O., Borregaard, N., Porse, B.T. and Theilgaard-Mönch, K.
Leukemia 29
(8): 1785-9.
August 2015
Kinin B1 and B2 receptor deficiency protects against obesity induced by a high-fat diet and improves glucose tolerance in mice.
Morais, R.L., Silva, E.D., Sales, V.M., Filippelli-Silva, R., Mori, M.A., Bader, M. and Pesquero, J.B.
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 8
: 399-407.
26 August 2015
Transcriptional control of tissue formation throughout root development.
Moreno-Risueno, M.A., Sozzani, R., Yardımcı, G.G., Petricka, J.J., Vernoux, T., Blilou, I., Alonso, J., Winter, C.M., Ohler, U., Scheres, B. and Benfey, P.N.
Science 350
(6259): 426-430.
23 October 2015
Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study.
Morgen, K., Schneider, M., Frölich, L., Tost, H., Plichta, M.M., Kölsch, H., Rakebrandt, F., Rienhoff, O., Jessen, F., Peters, O., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H.J., Schröder, J., Hampel, H., Teipel, S.J., Pantel, J., Heuser, I., Wiltfang, J., Rüther, E., Kornhuber, J., Maier, W. and Meyer-Lindenberg, A.
Alzheimer's Research & Therapy 7
(1): 27.
15 May 2015
Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin.
Mosienko, V., Beis, D., Alenina, N. and Woehr, M.
Molecular Autism 6
: 13.
8 March 2015
Life without brain serotonin: reevaluation of serotonin function with mice deficient in brain serotonin synthesis.
Mosienko, V., Beis, D., Pasqualetti, M., Waider, J., Matthes, S., Qadri, F., Bader, M. and Alenina, N.
Behavioural Brain Research 277
(SI): 78-88.
15 January 2015
Chamber identity programs drive early functional partitioning of the heart.
Mosimann, C., Panáková, D., Werdich, A.A., Musso, G., Burger, A., Lawson, K.L., Carr, L.A., Nevis, K.R., Sabeh, M.K, Zhou, Y., Davidson, A.J., DiBiase, A., Burns, C.E., Burns, C.G., MacRae, C.A. and Zon, L.I.
Nature Communications 6
: 8146.
26 August 2015
Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation.
Mossakowski, A.A., Pohlan, J., Bremer, D., Lindquist, R., Millward, J.M., Bock, M., Pollok, K., Mothes, R., Viohl, L., Radbruch, M., Gerhard, J., Bellmann-Strobl, J., Behrens, J., Infante-Duarte, C., Mähler, A., Boschmann, M., Rinnenthal, J.L., Füchtemeier, M., Herz, J., Pache, F.C., Bardua, M., Priller, J., Hauser, A.E., Paul, F., Niesner, R. and Radbruch, H.
Acta Neuropathologica 130
(6): 799-814.
December 2015
Sources of dynamic variability in NF-κB signal transduction: a mechanistic model.
Mothes, J., Busse, D., Kofahl, B. and Wolf, J.
BioEssays 37
(4): 452-462.
April 2015
Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.
Moussaieff, A., Rouleau, M., Kitsberg, D., Cohen, M., Levy, G., Barasch, D., Nemirovski, A., Shen-Orr, S., Laevsky, I., Amit, M., Bomze, D., Elena-Herrmann, B., Scherf, T., Nissim-Rafinia, M., Kempa, S., Itskovitz-Eldor, J., Meshorer, E., Aberdam, D. and Nahmias, Y.
Cell Metabolism 21
(3): 392-402.
3 March 2015
Anti-inflammatory effects of atorvastatin treatment in chronic obstructive pulmonary disease. A controlled pilot study.
Mroz, R.M., Lisowski, P., Tycinska, A., Bierla, J., Trzeciak, P.Z., Minarowski, L., Milewski, R., Lisowska, A., Boros, P., Sobkowicz, B., Duszewska, A.M., Chyczewska, E., Musial, W.J. and MacNee, W.
Journal of Physiology and Pharmacology 66
(1): 111-128.
February 2015
A multicenter cardiovascular MR network for tele-training and beyond: setup and initial experiences.
Muehlberg, F., Neumann, D., von Knobelsdorff-Brenkenhoff, F., Traber, J., Alwardt, N. and Schulz-Menger, J.
Journal of the American College of Radiology 12
(8): 876-883.
August 2015
High prevalence of anaemia among African migrants in Germany persists after exclusion of iron deficiency and erythrocyte polymorphisms.
Mueller, S.A., Amoah, S.K.B., Meese, S., Spranger, J. and Mockenhaupt, F.P.
Tropical Medicine & International Health 20
(9): 1180-1189.
September 2015
The macromolecular crystallography beamlines at BESSY II of the Helmholtz-Zentrum Berlin: current status and perspectives.
Mueller, U., Foerster, R., Hellmig, M., Huschmann, F.U., Kastner, A., Malecki, P., Puehringer, S., Roewer, M., Sparta, K., Steffien, M., Uehlein, M., Wilk, P. and Weiss, M.S.
European Physical Journal Plus 130
(7): 141.
July 2015
Passive cardiovascular implants in magnetic resonance imaging: Statement of the German Cardiac Society on the safety of magnetic resonance imaging [Passive kardiovaskulaere Implantate in der Magnetresonanztomographie: Stellungnahme der Deutschen Gesellschaft fuer Kardiologie - Herz- und Kreislaufforschung zur Sicherheit der Magnetresonanztomographie].
Muellerleile, K., Kolb, C., Rittger, H., Rybak, K., Tillmans, C., Wiegand, U., Sechtem, U., Kelm, M. and Schulz-Menger, J.
Kardiologe 9
(4): 303-309.
August 2015
Roles of microRNAs in B lymphocyte physiology and oncogenesis.
Muljo, S.A. and Rajewsky, K.
In:
Molecular Biology of B Cells.
Academic Press, 65-73.
ISBN 978-0-12-397933-9
2015
RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.
Murakawa, Y., Hinz, M., Mothes, J., Schuetz, A., Uhl, M., Wyler, E., Yasuda, T., Mastrobuoni, G., Friedel, C.C., Dölken, L., Kempa, S., Schmidt-Supprian, M., Blüthgen, N., Backofen, R., Heinemann, U., Wolf, J., Scheidereit, C. and Landthaler, M.
Nature Communications 6
: 7367.
14 July 2015
Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators.
Musso, G., Mosimann, C., Panáková, D., Burger, A., Zhou, Y., Zon, L.I. and MacRae, C.A.
Genomics Data 6
: 199-201.
December 2015
Metabolic response to epigallocatechin-3-gallate in relapsing-remitting multiple sclerosis: a randomized clinical trial.
Mähler, A., Steiniger, J., Bock, M., Klug, L., Parreidt, N., Lorenz, M., Zimmermann, B.F., Krannich, A., Paul, F. and Boschmann, M.
American Journal of Clinical Nutrition 101
(3): 487-495.
March 2015
N
Emerging role of tyrosine kinases as drugable targets in cancer.
Na, I.K. and Le Coutre, P.
Biomarker Insights 10
(S3): 29-31.
10 September 2015
Structure of a bacterial type III secretion system in contact with a host membrane in situ.
Nans, A., Kudryashev, M., Saibil, H.R. and Hayward, R.D.
Nature Communications 6
: 10114.
11 December 2015
Specific microRNAs regulate heat stress responses in Caenorhabditis elegans.
Nehammer, C., Podolska, A., Mackowiak, S.D., Kagias, K. and Pocock, R.
Scientific Reports 5
: 8866.
9 March 2015
Improved approach for chondrogenic differentiation of human induced pluripotent stem cells.
Nejadnik, H., Diecke, S., Lenkov, O.D., Chapelin, F., Donig, J., Tong, X., Derugin, N., Chan, R.C.F., Gaur, A., Yang, F., Wu, J.C. and Daldrup-Link, H.E.
Stem Cell Reviews and Reports 11
(2): 242-253.
April 2015
BCR-ABL1 acute myeloid leukemia: clonal selection of a BCR-ABL1(-) subclone as a cause of refractory disease with nilotinib treatment.
Neuendorff, N.R., Schwarz, M., Hemmati, P., Tuerkmen, S., Bommer, C., Burmeister, T., Doerken, B., le Coutre, P., Arnold, R. and Westermann, J.
Acta Haematologica 133
(2): 237-241.
2015
Gene gun Her2/neu DNA vaccination: evaluation of vaccine efficacy in a syngeneic Her2/neu mouse tumor model.
Nguyen-Hoai, T., Pezzutto, A. and Westermann, J.
Methods in Molecular Biology 1317
: 17-37.
2015
How bold is blood oxygenation level dependent (BOLD) magnetic resonance imaging of the kidney? Opportunities, challenges and future directions.
Niendorf, T., Pohlmann, A., Arakelyan, K., Flemming, B., Cantow, K., Hentschel, J., Grosenick, D., Ladwig, M., Reimann, H., Klix, S., Waiczies, S. and Seeliger, E.
Acta Physiologica 213
(1): 19-38.
January 2015
Advancing cardiovascular, neurovascular, and renal magnetic resonance imaging in small rodents using cryogenic radiofrequency coil technology.
Niendorf, T., Pohlmann, A., Reimann, H.M., Waiczies, H., Peper, E., Huelnhagen, T., Seeliger, E., Schreiber, A., Kettritz, R., Strobel, K., Ku, M.C. and Waiczies, S.
Frontiers in Pharmacology 6
: 255.
12 November 2015
Association of CRP genetic variants with blood concentrations of C-reactive protein and colorectal cancer risk.
Nimptsch, K., Aleksandrova, K., Boeing, H., Janke, J., Lee, Y.A., Jenab, M., Bueno-De-Mesquita, B.H., Jansen, E.H.J.M., Tsilidis, K.K., Trichopoulou, A., Weiderpass, E., Wu, C., Overvad, K., Tjønneland, A., Boutron-Ruault, M.C., Dossus, L., Racine, A., Kaaks, R., Canzian, F., Lagiou, P., Trichopoulos, D., Palli, D., Agnoli, C., Tumino, R., Vineis, P., Panico, S., Johansson, A., VanGuelpen, B., Khaw, K.T., Wareham, N., Peeters, P.H., Quirós, J.R., Venceslá García, A., Molina-Montes, E., Dorronsoro, M., Chirlaque, M.D., Gurrea, A.B., Key, T.J., Duarte-Salles, T., Stepien, M., Gunter, M.J., Riboli, E. and Pischon, T.
International Journal of Cancer 136
(5): 1181-1192.
1 March 2015
Plasma fetuin-A concentration, genetic variation in the AHSG gene and risk of colorectal cancer.
Nimptsch, K., Aleksandrova, K., Boeing, H., Janke, J., Lee, Y.A., Jenab, M., Yeon Kong, S., Tsilidis, K.K., Weiderpass, E., Bueno-De-Mesquita, B.H., Siersema, P.D., Jansen, E.H.J.M., Trichopoulou, A., Tjønneland, A., Olsen, A., Wu, C., Overvad, K., Boutron-Ruault, M.C., Racine, A., Freisling, H., Katzke, V., Kaaks, R., Lagiou, P., Trichopoulos, D., Severi, G., Naccarati, A., Mattiello, A., Palli, D., Grioni, S., Tumino, R., Peeters, P.H., Ljuslinder, I., Nyström, H., Brändstedt, J., Sánchez, M.J., Barricarte Gurrea, A., Bonet Bonet, C., Chirlaque, M.D., Dorronsoro, M., Quirós, J.R., Travis, R.C., Khaw, K.T., Wareham, N., Riboli, E., Gunter, M.J. and Pischon, T.
International Journal of Cancer 137
(4): 911-920.
15 August 2015
Association between dietary factors and plasma fetuin-A concentrations in the general population.
Nimptsch, K., Janke, J., Pischon, T. and Linseisen, J.
British Journal of Nutrition 114
(8): 1278-1285.
28 October 2015
Body fatness, related biomarkers and cancer risk: an epidemiological perspective.
Nimptsch, K. and Pischon, T.
Hormone Molecular Biology and Clinical Investigation 22
(2): 39-51.
May 2015
O
Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice.
Obenaus, M., Leitão, C., Leisegang, M., Chen, X., Gavvovidis, I., van der Bruggen, P., Uckert, W., Schendel, D.J. and Blankenstein, T.
Nature Biotechnology 33
(4): 402-407.
April 2015
Reliability of intra-retinal layer thickness estimates.
Oberwahrenbrock, T., Weinhold, M., Mikolajczak, J., Zimmermann, H., Paul, F., Beckers, I. and Brandt, A.U.
PLoS ONE 10
(9): e0137316.
8 September 2015
Reconstructing gene regulatory dynamics from high-dimensional single-cell snapshot data.
Ocone, A., Haghverdi, L., Mueller, N.S. and Theis, F.J.
Bioinformatics 31
(12): i89-i96.
15 June 2015
Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Oden, F., Marino, S.F., Brand, J., Scheu, S., Kriegel, C., Olal, D., Takvorian, A., Westermann, J., Yilmaz, B., Hinz, M., Daumke, O., Höpken, U.E., Müller, G. and Lipp, M.
Molecular Oncology 9
(7): 1348-1358.
August 2015
Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions.
Oeder, S., Kanashova, T., Sippula, O., Sapcariu, S.C., Streibel, T., Arteaga-Salas, J.M., Passig, J., Dilger, M., Paur, H.R., Schlager, C., Muelhopt, S., Diabate, S., Weiss, C., Stengel, B., Rabe, R., Harndorf, H., Torvela, T., Jokiniemi, J.K., Hirvonen, M.R., Schmidt-Weber, C., Traidl-Hoffmann, C., BeruBe, K.A., Wlodarczyk, A.J., Prytherch, Z., Michalke, B., Krebs, T., Prevot, A.S.H., Kelbg, M., Tiggesbaeumker, J., Karg, E., Jakobi, G., Scholtes, S., Schnelle-Kreis, J., Lintelmann, J., Matuschek, G., Sklorz, M., Klingbeil, S., Orasche, J., Richthammer, P., Mueller, L., Elsasser, M., Reda, A., Groeger, T., Weggler, B., Schwemer, T., Czech, H., Rueger, C.P., Abbaszade, G., Radischat, C., Hiller, K., Buters, J.T.M., Dittmar, G. and Zimmermann, R.
PLoS ONE 10
(6): e0126536.
3 June 2015
Loss-of-function GAS8 mutations cause primary ciliary dyskinesia and disrupt the nexin-dynein regulatory complex.
Olbrich, H., Cremers, C., Loges, N.T., Werner, C., Nielsen, K.G., Marthin, J.K., Philipsen, M., Wallmeier, J., Pennekamp, P., Menchen, T., Edelbusch, C., Dougherty, G.W., Schwartz, O., Thiele, H., Altmüller, J., Rommelmann, F. and Omran, H.
American Journal of Human Genetics 97
(4): 546-54.
1 October 2015
Mas receptor deficiency exacerbates lipopolysaccharide-induced cerebral and systemic inflammation in mice.
Oliveira-Lima, O.C., Pinto, M.C.X., Duchene, J., Qadri, F., Souza, L.L., Alenina, N., Bader, M., Santos, R.A.S. and Carvalho-Tavares, J.
Immunobiology 220
(12): 1311-1321.
December 2015
ASICs and mammalian mechanoreceptor function.
Omerbašić, D., Schuhmacher, L.N., Bernal Sierra, Y.A., Smith, E.S.J. and Lewin, G.R.
Neuropharmacology 94
: 80-86.
July 2015
Microfluidic single-cell analysis of transplanted human induced pluripotent stem cell-derived cardiomyocytes after acute myocardial infarction.
Ong, S.G., Huber, B.C., Lee, W.H., Kodo, K., Ebert, A.D., Ma, Y., Nguyen, P.K., Diecke, S., Chen, W.Y. and Wu, J.C.
Circulation 132
(8): 762-771.
25 August 2015
Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia.
Opel, D., Schnaiter, A., Dodier, D., Jovanovic, M., Gerhardinger, A., Idler, I., Mertens, D., Bullinger, L., Stilgenbauer, S. and Fulda, S.
International Journal of Cancer 137
(12): 2959-2970.
15 December 2015
A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Opitz, R., Mueller, M., Reuter, C., Barone, M., Soicke, A., Roske, Y., Piotukh, K., Huy, P., Beerbaum, M., Wiesner, B., Beyermann, M., Schmieder, P., Freund, C., Volkmer, R., Oschkinat, H., Schmalz, H.G. and Kuehne, R.
Proceedings of the National Academy of Sciences of the United States of America 112
(16): 5011-5016.
21 April 2015
Integrated transcriptome and proteome analyses reveal organ-specific proteome deterioration in old rats.
Ori, A., Toyama, B.H., Harris, M.S., Bock, T., Iskar, M., Bork, P., Ingolia, N.T., Hetzer, M.W. and Beck, M.
Cell Systems 1
(3): 224-237.
23 September 2015
Development of an online-SPE-LC-MS/MS method for 26 hydroxylated polyunsaturated fatty acids as rapid targeted metabolomics approach for the LOX, CYP, and autoxidation pathways of the arachidonic acid cascade.
Ostermann, A.I., Willenberg, I., Weylandt, K.H. and Schebb, N.H.
Chromatographia 78
(5-6): 415-428.
1 March 2015
The B-cell antigen receptor integrates adaptive and innate immune signals.
Otipoby, K.L., Waisman, A., Derudder, E., Srinivasan, L., Franklin, A. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 112
(39): 12145-12150.
29 September 2015
Online CBT in patients with multiple sclerosis and depression.
Otte, C.
Lancet Psychiatry 2
(3): 192-193.
March 2015
Vortioxetin und kognitive Funktion bei der Major Depression: Evidenz aus praeklinischen und klinischen Studien [Vortioxetine and cognitive function in major depression: evidence from preclinical and clinical studies].
Otte, C.
Psychopharmakotherapie 22
(1): 25-34.
February 2015
Mineralocorticoid receptor stimulation improves cognitive function and decreases cortisol secretion in depressed patients and healthy individuals.
Otte, C., Wingenfeld, K., Kuehl, L.K., Kaczmarczyk, M., Richter, S., Quante, A., Regen, F., Bajbouj, M., Zimmermann-Viehoff, F., Wiedemann, K. and Hinkelmann, K.
Neuropsychopharmacology 40
(2): 386-393.
January 2015
Cognitive function in older adults with major depression: effects of mineralocorticoid receptor stimulation.
Otte, C., Wingenfeld, K., Kuehl, L.K., Richter, S., Regen, F., Piber, D. and Hinkelmann, K.
Journal of Psychiatric Research 69
: 120-125.
October 2015
P
Oncoleaking: use of the pore-forming clostridium perfringens enterotoxin (CPE) for suicide gene therapy.
Pahle, J., Aumann, J., Kobelt, D. and Walther, W.
Methods in Molecular Biology 1317
: 69-85.
2015
Demographic and clinical features of neuromyelitis optica: A review.
Pandit, L., Asgari, N., Apiwattanakul, M., Palace, J., Paul, F., Leite, M.I., Kleiter, I. and Chitnis, T.
Multiple Sclerosis Journal 21
(7): 845-853.
June 2015
A Genome-wide CRISPR screen in primary immune cells to dissect regulatory networks.
Parnas, O., Jovanovic, M., Eisenhaure, T.M., Herbst, R.H., Dixit, A., Ye, C.J., Przybylski, D., Platt, R.J., Tirosh, I., Sanjana, N.E., Shalem, O., Satija, R., Raychowdhury, R., Mertins, P., Carr, S.A., Zhang, F., Hacohen, N. and Regev, A.
Cell 162
(3): 675-686.
30 July 2015
ASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study Group.
Paschka, P., Schlenk, R.F., Gaidzik, V.I., Herzig, J.K., Aulitzky, T., Bullinger, L., Späth, D., Teleanu, V., Kündgen, A., Köhne, C.H., Brossart, P., Held, G., Horst, H.A., Ringhoffer, M., Götze, K., Nachbaur, D., Kindler, T., Heuser, M., Thol, F., Ganser, A., Döhner, H. and Döhner, K.
Haematologica 100
(3): 324-330.
March 2015
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D.P., Curtin, J.A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A.C., Thyssen, J.P., den Dekker, H.T., Ferreira, M.A., Altmaier, E., Sleiman, P.M.A., Xiao, F.L., Gonzalez, J.R., Marenholz, I., Kalb, B., Pino-Yanes, M., Xu, C.J., Carstensen, L., Groen-Blokhuis, M.M., Venturini, C., Pennell, C.E., Barton, S.J., Levin, A.M., Curjuric, I., Bustamante, M., Kreiner-Møller, E., Lockett, G.A., Bacelis, J., Bunyavanich, S., Myers, R.A., Matanovic, A., Kumar, A., Tung, J.Y., Hirota, T., Kubo, M., McArdle, W.L., Henderson, A.J., Kemp, J.P., Zheng, J., Smith, G.D., Rüschendorf, F., Bauerfeind, A., Lee-Kirsch, M.A., Arnold, A., Homuth, G., Schmidt, C.O., Mangold, E., Cichon, S., Keil, T., Rodríguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Fölster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L.L., Grarup, N., de Jongste, J.C., Rivadeneira, F., Hofman, A., Jaddoe, V.W.V., Pasmans, S.G.M.A., Elbert, N.J., Uitterlinden, A.G., Marks, G.B., Thompson, P.J., Matheson, M.C., Robertson, C.F., Ried, J.S., Li, J., Zuo, X.B., Zheng, X.D., Yin, X.Y., Sun, L.D., McAleer, M.A., O'Regan, G.M., Fahy, C.M.R., Campbell, L.E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D.S., Feenstra, B., Geller, F., Hottenga, J.J., Middeldorp, C.M., Hysi, P., Bataille, V., Spector, T., Tiesler, C.M.T., Thiering, E., Pahukasahasram, B., Yang, J.J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C.L., Myhre, R., Nystad, W., Custovic, A., Weiss, S.T., Meyers, D.A., Söderhäll, C., Melén, E., Ober, C., Raby, B.A., Simpson, A., Jacobsson, B., Holloway, J.W., Bisgaard, H., Sunyer, J., Probst-Hensch, N.M., Williams, L.K., Godfrey, K.M., Wang, C.A., Boomsma, D.I., Melbye, M., Koppelman, G.H., Jarvis, D., McLean, W.H.I., Irvine, A.D., Zhang, X.J., Hakonarson, H., Gieger, C., Burchard, E.G., Martin, N.G., Duijts, L., Linneberg, A., Jarvelin, M.R., Noethen, M.M., Lau, S., Hübner, N., Lee, Y.A., Tamari, M., Hinds, D.A., Glass, D., Brown, S.J., Heinrich, J., Evans, D.M. and Weidinger, S.
Nature Genetics 47
(12): 1449-1456.
December 2015
Current immunotherapy of multiple sclerosis [Aktuelle Immuntherapie der Multiplen Sklerose].
Paul, F. and Ruprecht, K.
Nervenarzt 86
(8): 1031-1044.
August 2015
Transcriptional heterogeneity and lineage commitment in myeloid progenitors.
Paul, F., Arkin, Y., Giladi, A., Jaitin, D.A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., David, E., Cohen, N., Lauridsen, F.K.B., Haas, S., Schlitzer, A., Mildner, A., Ginhoux, F., Jung, S., Trumpp, A., Porse, B.T., Tanay, A. and Amit, I.
Cell 163
(7): 1663-1677.
17 December 2015
Diffusion-sensitized ophthalmic magnetic resonance imaging free of geometric distortion at 3.0 and 7.0 T: a feasibility study in healthy subjects and patients with intraocular masses.
Paul, K., Graessl, A., Rieger, J., Lysiak, D., Huelnhagen, T., Winter, L., Heidemann, R., Lindner, T., Hadlich, S., Zimpfer, A., Pohlmann, A., Endemann, B., Krüger, P.C., Langner, S., Stachs, O. and Niendorf, T.
Investigative Radiology 50
(5): 309-321.
May 2015
Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Peifer, M., Hertwig, F., Roels, F., Dreidax, D., Gartlgruber, M., Menon, R., Krämer, A., Roncaioli, J.L., Sand, F., Heuckmann, J.M., Ikram, F., Schmidt, R., Ackermann, S., Engesser, A., Kahlert, Y., Vogel, W., Altmüller, J., Nürnberg, P., Thierry-Mieg, J., Thierry-Mieg, D., Mariappan, A., Heynck, S., Mariotti, E., Henrich, K.O., Gloeckner, C., Bosco, G., Leuschner, I., Schweiger, M.R., Savelyeva, L., Watkins, S.C., Shao, C., Bell, E., Höfer, T., Achter, V., Lang, U., Theissen, J., Volland, R., Saadati, M., Eggert, A., de Wilde, B., Berthold, F., Peng, Z., Zhao, C., Shi, L., Ortmann, M., Büttner, R., Perner, S., Hero, B., Schramm, A., Schulte, J.H., Herrmann, C., O'Sullivan, R.J., Westermann, F., Thomas, R.K. and Fischer, M.
Nature 526
(7575): 700-704.
29 October 2015
Efficacy of prophylactic low-molecular weight heparin for ambulatory patients with advanced pancreatic cancer: outcomes from the CONKO-004 trial.
Pelzer, U., Opitz, B., Deutschinoff, G., Stauch, M., Reitzig, P.C., Hahnfeld, S., Mueller, L., Grunewald, M., Stieler, J.M., Sinn, M., Denecke, T., Bischoff, S., Oettle, H., Doerken, B. and Riess, H.
Journal of Clinical Oncology 33
(18): 2028-2034.
20 June 2015
CCN1 mutation is associated with atrial septal defect.
Perrot, A., Schmitt, K.R., Roth, E.M., Stiller, B., Posch, M.G., Browne, E.N.L., Timmann, C., Horstmann, R.D., Berger, F. and Ozcelik, C.
Pediatric Cardiology 36
(2): 295-299.
February 2015
Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naive patients with mild-to-moderate Alzheimer's disease.
Peters, O., Fuentes, M., Joachim, L.K., Jessen, F., Luckhaus, C., Kornhuber, J., Pantel, J., Huell, M., Schmidtke, K., Ruether, E., Moeller, H.J., Kurz, A., Wiltfang, J., Maier, W., Wiese, B., Froelich, L. and Heuser, I.
Alzheimer's and Dementia 1
(3): 198-204.
November 2015
Anti-CD22 and anti-CD79B antibody drug conjugates are active in different molecular diffuse large B-cell lymphoma subtypes.
Pfeifer, M., Zheng, B., Erdmann, T., Koeppen, H., McCord, R., Grau, M., Staiger, A., Chai, A., Sandmann, T., Madle, H., Doerken, B., Chu, Y.W., Chen, A.I., Lebovic, D., Salles, G.A., Czuczman, M.S., Palanca-Wessels, M.C., Press, O.W., Advani, R., Morschhauser, F., Cheson, B.D., Lenz, P., Ott, G., Polson, A.G., Mundt, K.E. and Lenz, G.
Leukemia 29
(7): 1578-1586.
July 2015
Assessing the bioenergetic profile of human pluripotent stem cells.
Pfiffer, V. and Prigione, A.
Methods in Molecular Biology 1264
: 279-288.
2015
Association of serum Epstein-Barr nuclear antigen-1 antibodies and intrathecal immunoglobulin synthesis in early multiple sclerosis.
Pfuhl, C., Oechtering, J., Rasche, L., Gieß, R.M., Behrens, J.R., Wakonig, K., Freitag, E., Pache, F.C., Otto, C., Hofmann, J., Eberspächer, B., Bellmann-Strobl, J., Paul, F. and Ruprecht, K.
Journal of Neuroimmunology 285
: 156-160.
15 August 2015
In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma.
Philipp-Abbrederis, K., Herrmann, K., Knop, S., Schottelius, M., Eiber, M., Lückerath, K., Pietschmann, E., Habringer, S., Gerngroß, C., Franke, K., Rudelius, M., Schirbel, A., Lapa, C., Schwamborn, K., Steidle, S., Hartmann, E., Rosenwald, A., Kropf, S., Beer, A.J., Peschel, C., Einsele, H., Buck, An.K., Schwaiger, M., Götze, K., Wester, H.J. and Keller, U.
EMBO Molecular Medicine 7
(4): 477-487.
1 April 2015
Dysferlin rescue by spliceosome-mediated pre-mRNA trans-splicing targeting introns harbouring weakly defined 3' splice sites.
Philippi, S., Lorain, S., Beley, C., Peccate, C., Precigout, G., Spuler, S. and Garcia, L.
Human Molecular Genetics 24
(14): 4049-4060.
15 July 2015
Effects of group psychotherapy, individual counseling, methylphenidate, and placebo in the treatment of adult attention-deficit/hyperactivity disorder: a randomized clinical trial.
Philipsen, A., Jans, T., Graf, E., Matthies, S., Borel, P., Colla, M., Gentschow, L., Langner, D., Jacob, C., Gross-Lesch, S., Sobanski, E., Alm, B., Schumacher-Stien, M., Roesler, M., Retz, W., Retz-Junginger, P., Kis, B., Abdel-Hamid, M., Heinrich, V., Huss, M., Kornmann, C., Buerger, A., Perlov, E., Ihorst, G., Schlander, M., Berger, M. and Tebartz van Elst, L.
JAMA Psychiatry 72
(12): 1199-1210.
December 2015
Formin-mediated actin polymerization at endothelial junctions is required for vessel lumen formation and stabilization.
Phng, L.K., Gebala, V., Bentley, K., Philippides, A., Wacker, A., Mathivet, T., Sauteur, L., Stanchi, F., Belting, H.G., Affolter, M. and Gerhardt, H.
Developmental Cell 32
(1): 123-132.
12 January 2015
An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.
Pienaar, I.S., Harrison, I.F., Elson, J.L., Bury, A., Woll, P., Simon, A.K. and Dexter, D.T.
Brain Structure & Function 220
(1): 479-500.
January 2015
BigDataViewer: visualization and processing for large image data sets.
Pietzsch, T., Saalfeld, S., Preibisch, S. and Tomancak, P.
Nature Methods 12
(6): 481-483.
28 May 2015
Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.
Planells-Cases, R., Lutter, D., Guyader, C., Gerhards, N.M., Ullrich, F., Elger, D.A., Kucukosmanoglu, A., Xu, G., Voss, F.K., Reincke, S.M., Stauber, T., Blomen, V.A., Vis, D.J., Wessels, L.F., Brummelkamp, T.R., Borst, P., Rottenberg, S. and Jentsch, T.J.
EMBO Journal 34
(24): 2993-3008.
December 2015
Studying axonal outgrowth and regeneration of the corticospinal tract in organotypic slice cultures.
Pohland, M., Glumm, R., Stoenica, L., Höltje, M., Kiwit, J., Ahnert-Hilger, G., Strauss, U., Bräuer, A.U., Paul, F. and Glumm, J.
Journal of Neurotrauma 32
(19): 1465-1477.
1 October 2015
Magnetic resonance imaging (MRI) analysis of ischemia/reperfusion in experimental acute renal injury.
Pohlmann, A., Arakelyan, K., Seeliger, E. and Niendorf, T.
Methods in Molecular Biology 1397
: 113-127.
17 December 2015
Three-dimensional genome architecture: players and mechanisms.
Pombo, A. and Dillon, N.
Nature Reviews Molecular Cell Biology 16
(4): 245-257.
April 2015
Sensory mechanotransduction at membrane-matrix interfaces.
Poole, K., Moroni, M. and Lewin, G.R.
Pfluegers Archiv European Journal of Physiology 467
(1): 121-132.
15 January 2015
Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type.
Popp, J., Wolfsgruber, S., Heuser, I., Peters, O., Huell, M., Schroeder, J., Moeller, H.J., Lewczuk, P., Schneider, A., Jahn, H., Luckhaus, C., Perneczky, R., Froelich, L., Wagner, M., Maier, W., Wiltfang, J., Kornhuber, J. and Jessen, F.
Neurobiology of Aging 36
(2): 601-607.
February 2015
A-kinase anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle.
Poppinga, W.J., Heijink, I.H., Holtzer, L.J., Skroblin, P., Klussmann, E., Halayko, A.J., Timens, W., Maarsingh, H. and Schmidt, M.
American Journal of Physiology Lung Cellular and Molecular Physiology 308
(8): L766-L775.
15 April 2015
A promoter polymorphism -945C>G in the connective tissue growth factor in heart failure patients with mechanical circulatory support: a new marker for bridge to recovery?
Posch, M.G., Schmidt, G., Steinhoff, L., Perrot, A., Drews, T., Dandel, M., Krabatsch, T., Hetzer, R. and Potapov, E.V.
European Journal of Cardio-Thoracic Surgery 47
(1): e29-e33.
2015
Altered microglial phagocytosis in GPR34-deficient mice.
Preissler, J., Grosche, A., Lede, V., Le Duc, D., Krügel, K., Matyash, V., Szulzewsky, F., Kallendrusch, S., Immig, K., Kettenmann, H., Bechmann, I., Schöneberg, T. and Schulz, A.
Glia 63
(2): 206-215.
February 2015
DBEndo: a web-based endodontic case management tool.
Preissner, S., Kostka, E., Mokross, M., Kersten, N.V., Blunck, U. and Preissner, R.
BMC Research Notes 8
: 685.
17 November 2015
Personalized cancer therapy considering cytochrome P450 variability.
Preissner, S., Simmaco, M., Gentile, G. and Preissner, R.
Advances in Pharmacology 74
(74): 113-130.
2015
Induced pluripotent stem cells (iPSCs) for modeling mitochondrial DNA disorders.
Prigione, A.
Methods in Molecular Biology 1265
: 349-356.
6 January 2015
Metabolic restructuring and cell fate conversion.
Prigione, A., Ruiz-Perez, M.V., Bukowiecki, R. and Adjaye, J.
Cellular and Molecular Life Sciences 72
(9): 1759-1777.
1 May 2015
Regulatory T cells ameliorate intrauterine growth retardation in a transgenic rat model for preeclampsia.
Przybyl, L., Ibrahim, T., Haase, N., Golic, M., Rugor, J., Luft, F.C., Bendix, I., Serdar, M., Wallukat, G., Staff, A.C., Müller, D.N., Hünig, T., Felderhoff-Müser, U., Herse, F., LaMarca, B. and Dechend, R.
Hypertension 65
(6): 1298-1306.
June 2015
Techniques for the detection of autophagy in primary mammalian cells.
Puleston, D., Phadwal, K., Watson, A.S., Soilleux, E.J., Chittaranjan, S., Bortnik, S., Gorski, S.M., Ktistakis, N. and Simon, A.K.
Cold Spring Harbor Protocols 2015
(9): pdb.top070391.
1 September 2015
New roles for autophagy and spermidine in T cells.
Puleston, D.J. and Simon, A.K.
Microbial Cell 2
(3): 91-93.
March 2015
Functional changes in the uterine artery precede the hypertensive phenotype in a transgenic model of hypertensive pregnancy.
Pulgar, V.M., Yamaleyeva, L.M., Varagic, J., McGee, C., Bader, M., Dechend, R. and Brosnihan, K.B.
American Journal of Physiology Endocrinology and Metabolism 309
(9): E811-E817.
1 November 2015
R
Arginase as a Critical Prooxidant Mediator in the Binomial Endothelial Dysfunction-Atherosclerosis.
Rabelo, L.A., Ferreira, F.O., Nunes-Souza, V., da Fonseca, L.J.S. and Goulart, M.O.F.
Oxidative Medicine and Cellular Longevity 2015
: 924860.
2015
Animal models with a genetic alteration of the ACE2/Ang-(1-7)/Mas axis.
Rabelo, L.A., Nunes-Souza, V. and Bader, M.
In:
The Protective Arm of the Renin Angiotensin System (RAS).
Elsevier, Amsterdam, NL, 161-168.
ISBN 9780128013649
2015
Treatment of young patients with HNF1A mutations (HNF1A-MODY).
Raile, K., Schober, E., Konrad, K., Thon, A., Grulich-Henn, J., Meissner, T., Woelfle, J., Scheuing, N. and Holl, R.W.
Diabetic Medicine 32
(4): 526-530.
April 2015
The Herzenberg lecture: how to make a B-1 cell?
Rajewsky, K.
Annals of the New York Academy of Sciences 1362
(1): 6-7.
December 2015
The DNA deamination model of somatic antibody diversification.
Rajewsky, K.
Journal of Immunology 194
(5): 2041-2042.
1 March 2015
Proteomic analysis of the ubiquitin landscape in the drosophila embryonic nervous system and the adult photoreceptor cells.
Ramirez, J., Martinez, A., Lectez, B., Lee, S.Y., Franco, M., Barrio, R., Dittmar, G. and Mayor, U.
PLoS ONE 10
(10): e0139083.
13 October 2015
Mechanical properties of branched actin filaments.
Razbin, M., Falcke, M., Benetatos, P. and Zippelius, A.
Physical Biology 12
(4): 046007.
4 June 2015
Rare variants in GABA(A) receptor genes in Rolandic epilepsy and related syndromes.
Reinthaler, E.M., Dejanovic, B., Lal, D., Semtner, M., Merkler, Y., Reinhold, A., Pittrich, D.A., Hotzy, C., Feucht, M., Steinboeck, H., Gruber-Sedlmayr, U., Ronen, G., Neophytou, B., Geldner, J., Haberlandt, E., Muhle, H., Ikram, M.A., van Duijn, CM., Uitterlinden, A.G., Hofman, A., Altmüller, J., Kawalia, A., Toliat, M.R., Nuernberg, P., Lerche, H., Nothnagel, M., Thiele, H., Sander, T., Meier, J.C., Schwarz, G., Neubauer, B.A. and Zimprich, F.
Annals of Neurology 77
(6): 972-986.
June 2015
Deletion of kinin B2 receptor alters muscle metabolism and exercise performance.
Reis, F.C.G., Haro, A.S., Bacurau, A.V.N., Hirabara, S.M., Wasinski, F., Ormanji, M.S., Moreira, J.B.N., Kiyomoto, B.H., Bertoncini, C.R.A., Brum, P.C., Curi, R., Bader, M., Bacurau, R.F.P., Pesquero, J.B. and Araújo, R.C.
PLoS ONE 10
(8): e0134844.
24 August 2015
Regulation of β1 integrin-Klf2-mediated angiogenesis by CCM proteins.
Renz, M., Otten, C., Faurobert, E., Rudolph, F., Zhu, Y., Boulday, G., Duchene, J., Mickoleit, M., Dietrich, A.C., Ramspacher, C., Steed, E., Manet-Dupe, S., Benz, A., Hassel, D., Vermot, J., Huisken, J., Tournier-Lasserve, E., Felbor, U., Sure, U., Albiges-Rizo, C. and Abdelilah-Seyfried, S.
Developmental Cell 32
(2): 181-190.
26 January 2015
Retrospectively-gated CINE (23)Na imaging of the heart at 7.0 Tesla using density-adapted 3D projection reconstruction.
Resetar, A., Hoffmann, S.H., Graessl, A., Winter, L., Waiczies, H., Ladd, M.E., Niendorf, T. and Nagel, A.M.
Magnetic Resonance Imaging 33
(9): 1091-1097.
November 2015
Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation.
Rettig, I., Koeneke, E., Trippel, F., Mueller, W.C., Burhenne, J., Kopp-Schneider, A., Fabian, J., Schober, A., Fernekorn, U., von Deimling, A., Deubzer, H.E., Milde, T., Witt, O. and Oehme, I.
Cell Death & Disease 6
: e1657.
19 February 2015
Crystal structure of the dynamin tetramer.
Reubold, T.F., Faelber, K., Plattner, N., Posor, Y., Ketel, K., Curth, U., Schlegel, J., Anand, R., Manstein, D.J., Noé, F., Haucke, V., Daumke, O. and Eschenburg, S.
Nature 525
(7569): 404-408.
17 September 2015
Cross-recognition of a myelin peptide by CD8(+) T cells in the CNS is not sufficient to promote neuronal damage.
Reuter, E., Gollan, R., Grohmann, N., Paterka, M., Salmon, H., Birkenstock, J., Richers, S., Leuenberger, T., Brandt, A.U., Kuhlmann, T., Zipp, F. and Siffrin, V.
Journal of Neuroscience 35
(12): 4837-4850.
25 March 2015
Role of sortilin in models of autoimmune neuroinflammation.
Reuter, E., Weber, J., Paterka, M., Ploen, R., Breiderhoff, T., van Horssen, J., Willnow, T.E., Siffrin, V. and Zipp, F.
Journal of Immunology 195
(12): 5762-5769.
15 December 2015
Uncertainty-driven forest predictors for vertebra localization and segmentation.
Richmond, D., Kainmueller, D., Glocker, B., Rother, C. and Myers, G.
Lecture Notes in Computer Science 9349
: 653-660.
2015
Retinal pathology in Susac syndrome detected by spectral-domain optical coherence tomography.
Ringelstein, M., Albrecht, P., Kleffner, I., Bühn, B., Harmel, J., Müller, A.K., Finis, D., Guthoff, R., Bergholz, R., Duning, T., Krämer, M., Paul, F., Brandt, A., Oberwahrenbrock, T., Mikolajczak, J., Wildemann, B., Jarius, S., Hartung, H.P., Aktas, O. and Dörr, J.
Neurology 85
(7): 610-618.
18 August 2015
State-dependencies of learning across brain scales.
Ritter, P., Born, J., Brecht, M., Dinse, H.R., Heinemann, U., Pleger, B., Schmitz, D., Schreiber, S., Villringer, A. and Kempter, R.
Frontiers in Computational Neuroscience 9
: 1.
26 February 2015
Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.
Roberts, A.M., Ware, J.S., Herman, D.S., Schafer, S., Baksi, J., Bick, A.G., Buchan, R.J., Walsh, R., John, S., Wilkinson, S., Mazzarotto, F., Felkin, L.E., Gong, S., MacArthur, J.A.L., Cunningham, F., Flannick, J., Gabriel, S.B., Altshuler, D.M., Macdonald, P.S., Heinig, M., Keogh, A.M., Hayward, C.S., Banner, N.R., Pennell, D.J., O'Regan, D.P., San, T.R., de Marvao, A., Dawes, T.J.W., Gulati, A., Birks, E.J., Yacoub, M.H., Radke, M., Gotthardt, M., Wilson, J.G., O'Donnell, C.J., Prasad, S.K., Barton, P.J.R., Fatkin, D., Hubner, N., Seidman, J.G., Seidman, C.E. and Cook, S.A.
Science Translational Medicine 7
(270): 270ra6.
14 January 2015
Intake of meat mutagens and risk of prostate cancer in a cohort of U.S. health professionals.
Rohrmann, S., Nimptsch, K., Sinha, R., Willett, W.C., Giovannucci, E.L., Platz, E.A. and Wu, K.
Cancer Epidemiology, Biomarkers & Prevention 24
(10): 1557-1563.
October 2015
Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.
Rohwer, N., Bindel, F., Grimm, C., Lin, S.J., Wappler, J., Klinger, B., Blüthgen, N., Du Bois, I., Schmeck, B., Lehrach, H., de Graauw, M., Goncalves, E., Saez-Rodriguez, J., Tan, P., Grabsch, H.I., Prigione, A., Kempa, S. and Cramer, T.
Oncotarget 7
(6): 6693-6710.
29 December 2015
Intrathecal heat shock protein 60 mediates neurodegeneration and demyelination in the CNS through a TLR4-and MyD88-dependent pathway.
Rosenberger, K., Dembny, P., Derkow, K., Engel, O., Krüger, C., Wolf, S.A., Kettenmann, H., Schott, E., Meisel, A. and Lehnardt, S.
Molecular Neurodegeneration 10
: 5.
26 February 2015
Mutations in XRCC4 cause primary microcephaly, short stature and increased genomic instability.
Rosin, N., Elcioglu, N.H., Beleggia, F., Isgüven, P., Altmüller, J., Thiele, H., Steindl, K., Joset, P., Rauch, A., Nürnberg, P., Wollnik, B. and Yigit, G.
Human Molecular Genetics 24
(13): 3708-3717.
1 July 2015
Optogenetic acidification of synaptic vesicles and lysosomes.
Rost, B.R., Schneider, F., Grauel, M.K., Wozny, C., Bentz, C.G., Blessing, A., Rosenmund, T., Jentsch, T.J., Schmitz, D., Hegemann, P. and Rosenmund, C.
Nature Neuroscience 18
(12): 1845-1852.
December 2015
The origins of ALK translocations.
Roukos, V. and Mathas, S.
Frontiers in Bioscience 7
: 260-268.
1 June 2015
Prospective, randomized comparison of gadopentetate and gadobutrol to assess chronic myocardial infarction applying cardiovascular magnetic resonance.
Rudolph, A., Messroghli, D., von Knobelsdorff-Brenkenhoff, F., Traber, J., Schüler, J., Wassmuth, R. and Schulz-Menger, J.
BMC Medical Imaging 15
(1): 55.
17 November 2015
Does Nrf2 help nerves to survive?
Ruprecht, K. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 2
(3): e105.
June 2015
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed.
Rybak-Wolf, A., Stottmeister, C., Glažar, P., Jens, M., Pino, N., Giusti, S., Hanan, M., Behm, M., Bartok, O., Ashwal-Fluss, R., Herzog, M., Schreyer, L., Papavasileiou, P., Ivanov, A., Öhman, M., Refojo, D., Kadener, S. and Rajewsky, N.
Molecular Cell 58
(5): 870-885.
4 June 2015
S
Central role of ULK1 in type I interferon signaling.
Saleiro, D., Mehrotra, S., Kroczynska, B., Beauchamp, E.M., Lisowski, P., Majchrzak-Kita, B., Bhagat, T.D., Stein, B.L., McMahon, B., Altman, J.K., Kosciuczuk, E.M., Baker, D.P., Jie, C., Jafari, N., Thompson, C.B., Levine, R.L., Fish, E.N., Verma, A.K. and Platanias, L.C.
Cell Reports 11
(4): 605-617.
28 April 2015
H2S- and NO-signaling pathways in Alzheimer's amyloid vasculopathy: synergism or antagonism?
Salmina, A.B., Komleva, Y.K., Szijártó, I.A., Gorina, Y.V., Lopatina, O.L., Gertsog, G.E., Filipovic, M.R. and Gollasch, M.
Frontiers in Physiology 6
: 361.
11 December 2015
Genetic etiology of renal agenesis: fine mapping of renag1 and identification of Kit as the candidate functional gene.
Samanas, N.B., Commers, T.W., Dennison, K.L., Harenda, Q.E., Kurz, S.G., Lachel, C.M., Wavrin, K.L., Bowler, M., Nijman, I.J., Guryev, V., Cuppen, E., Hubner, N., Sullivan, R., Vezina, C.M. and Shull, J.D.
PLoS ONE 10
(2): e0118147.
18 February 2015
PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones.
Sander, S., Chu, V.T., Yasuda, T., Franklin, A., Graf, R., Calado, D.P., Li, S., Imami, K., Selbach, M., Di Virgilio, M., Bullinger, L. and Rajewsky, K.
Immunity 43
(6): 1075-1086.
15 December 2015
X-linked macrocytic dyserythropoietic anemia in females with an ALAS2 mutation.
Sankaran, V.G., Ulirsch, J.C., Tchaikovskii, V., Ludwig, L.S., Wakabayashi, A., Kadirvel, S., Lindsley, R.C., Bejar, R., Shi, J., Lovitch, S.B., Bishop, D.F. and Steensma, D.P.
Journal of Clinical Investigation 125
(4): 1665-1669.
1 April 2015
Ligands for the nuclear peroxisome proliferator-activated receptor gamma.
Sauer, S.
Trends in Pharmacological Sciences 36
(10): 688-704.
October 2015
Nutriproteomics: facts, concepts, and perspectives.
Sauer, S. and Luge, T.
Proteomics 15
(5-6): 997-1013.
March 2015
Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML-Study IV.
Saussele, S., Krauss, M.P., Hehlmann, R., Lauseker, M., Proetel, U., Kalmanti, L., Hanfstein, B., Fabarius, A., Kraemer, D., Berdel, W.E., Bentz, M., Staib, P., de Wit, M., Wernli, M., Zettl, F., Hebart, H.F., Hahn, M., Heymanns, J., Schmidt-Wolf, I., Schmitz, N., Eckart, M.J., Gassmann, W., Bartholomaeus, A., Pezzutto, A., Oppliger Leibundgut, E., Heim, D., Krause, S.W., Burchert, A., Hofmann, W.K., Hasford, J., Hochhaus, A., Pfirrmann, M. and Müller, M.C.
Blood 126
(1): 42-49.
2 July 2015
Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing.
Schaafsma, W., Zhang, X., van Zomeren, K.C., Jacobs, S., Georgieva, P.B., Wolf, S.A., Kettenmann, H., Janova, H., Saiepour, N., Hanisch, U.K., Meerlo, P., van den Elsen, P.J., Brouwer, N., Boddeke, H.W.G.M. and Eggen, B.J.L.
Brain Behavior and Immunity 48
: 205-221.
August 2015
A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis.
Schaarschmidt, H., Ellinghaus, D., Rodríguez, E., Kretschmer, A., Baurecht, H., Lipinski, S., Meyer-Hoffert, U., Harder, J., Lieb, W., Novak, N., Fölster-Holst, R., Esparza-Gordillo, J., Marenholz, I., Ruschendorf, F., Hubner, N., Reischl, E., Waldenberger, M., Gieger, C., Illig, T., Kabesch, M., Zhang, X.J., Xiao, F.L., Lee, Y.A., Franke, A. and Weidinger, S.
Journal of Allergy and Clinical Immunology 136
(3): 802-806.
September 2015
Loss of Gadkin affects dendritic cell migration in vitro.
Schachtner, H., Weimershaus, M., Stache, V., Plewa, N., Legler, D.F., Höpken, U.E. and Maritzen, T.
PLoS ONE 10
(12): e0143883.
1 December 2015
Translational regulation shapes the molecular landscape of complex disease phenotypes.
Schafer, S., Adami, E., Heinig, M., Costa Rodrigues, K.E., Kreuchwig, F., Silhavy, J., van Heesch, S., Simaite, D., Rajewsky, N., Cuppen, E., Pravenec, M., Vingron, M., Cook, S.A. and Hubner, N.
Nature Communications 6
: 7200.
26 May 2015
Alternative splicing signatures in RNA-seq data: percent spliced in (PSI).
Schafer, S., Miao, K., Benson, C.C., Heinig, M., Cook, S.A. and Hubner, N.
Current Protocols in Human Genetics 87
: 11.16.1-11.16.14.
6 October 2015
Rapid multiplex analysis of lipid raft components with single-cell resolution.
Schatzlmaier, P., Supper, V., Göschl, L., Zwirzitz, A., Eckerstorfer, P., Ellmeier, W., Huppa, J.B. and Stockinger, H.
Science Signaling 8
(395): rs11.
September 2015
Podocyte-specific deletion of murine CXADR does not impair podocyte development, function or stress response.
Schell, C., Kretz, O., Bregenzer, A., Rogg, M., Helmstädter, M., Lisewski, U., Gotthardt, M., Tharaux, P.L., Huber, T.B. and Grahammer, F.
PLoS ONE 10
(6): e0129424.
15 June 2015
Insulin resistance in heart failure: differences between patients with reduced and preserved left ventricular ejection fraction.
Scherbakov, N., Bauer, M., Sandek, A., Szabo, T., Toepper, A., Jankowska, E.A., Springer, J., von Haehling, S., Anker, S.D., Lainscak, M., Engeli, S., Duengen, H.D. and Doehner, W.
European Journal of Heart Failure 17
(10): 1015-1021.
October 2015
The murine model of mucopolysaccharidosis IIIB develops cardiopathies over time leading to heart failure.
Schiattarella, G.G., Cerulo, G., De Pasquale, V., Cocchiaro, P., Paciello, O., Avallone, L., Belfiore, M.P., Iacobellis, F., Di Napoli, D., Magliulo, F., Perrino, C., Trimarco, B., Esposito, G., Di Natale, P. and Pavone, L.M.
PLoS ONE 10
(7): e0131662.
6 July 2015
Inhibition of hypertrophy is a good therapeutic strategy in ventricular pressure overload.
Schiattarella, G.G. and Hill, J.A.
Circulation 131
(16): 1435-47.
21 April 2015
Response to Crozatier and Ventura-Clapier.
Schiattarella, G.G. and Hill, J.A.
Circulation 131
(16): 1457.
21 April 2015
Novel molecular approaches in heart failure: seven trans-membrane receptors signaling in the heart and circulating blood leukocytes.
Schiattarella, G.G., Magliulo, F., Cattaneo, F., Gargiulo, G., Sannino, A., Franzone, A., Oliveti, M., Perrino, C., Trimarco, B. and Esposito, G.
Frontiers in Cardiovascular Medicine 2
: 13.
16 March 2015
Primary percutaneous coronary intervention in a patient with acute inferior myocardial infarction and agenesis of right coronary artery. "In search of a coronary ostium".
Schiattarella, G.G., Magliulo, F., Palma, V., Esposito, G. and Cirillo, P.
Cardiology and Angiology 3
(3): 157-161.
27 April 2015
Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria.
Schippling, S., Balk, L., Costello, F., Albrecht, P., Balcer, L., Calabresi, P., Frederiksen, J., Frohman, E., Green, A., Klistorner, A., Outteryck, O., Paul, F., Plant, G., Traber, G., Vermersch, P., Villoslada, P., Wolf, S. and Petzold, A.
Multiple Sclerosis Journal 21
(2): 163-170.
February 2015
Treating hypertension in pregnancy.
Schlembach, D., Homuth, V. and Dechend, R.
Current Hypertension Reports 17
: 63.
July 2015
Body weight gain and risk of colorectal cancer: a systematic review and meta-analysis of observational studies.
Schlesinger, S., Lieb, W., Koch, M., Fedirko, V., Dahm, C.C., Pischon, T., Nöthlings, U., Boeing, H. and Aleksandrova, K.
Obesity Reviews 16
(7): 607-619.
July 2015
Flow cytometric maturity score as a novel prognostic parameter in patients with acute myeloid leukemia.
Schneider, T., Flörcken, A., Singh, A., Türkmen, S., Burmeister, T., Anagnostopoulos, I., Pezzutto, A., Dörken, B. and Westermann, J.
Annals of Hematology 94
(8): 1337-1345.
August 2015
Leukemic progenitor cells are susceptible to targeting by stimulated cytotoxic T cells against immunogenic leukemia-associated antigens.
Schneider, V., Zhang, L., Rojewski, M., Fekete, N., Schrezenmeier, H., Erle, A., Bullinger, L., Hofmann, S., Götz, M., Döhner, K., Ihme, S., Döhner, H., Buske, C., Feuring-Buske, M. and Greiner, J.
International Journal of Cancer 137
(9): 2083-2092.
1 November 2015
Epo-induced erythroid maturation is dependent on Plcγ1 signaling.
Schnöder, T.M., Arreba-Tutusaus, P., Griehl, I., Bullinger, L., Buschbeck, M., Lane, S.W., Döhner, K., Plass, C., Lipka, D.B., Heidel, F.H. and Fischer, T.
Cell Death and Differentiation 22
(6): 974-985.
June 2015
Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Schoors, S., Bruning, U., Missiaen, R., Queiroz, K.C.S., Borgers, G., Elia, I., Zecchin, A., Cantelmo, A.R., Christen, S., Goveia, J., Heggermont, W., Goddé, L., Vinckier, S., Van Veldhoven, P.P., Eelen, G., Schoonjans, L., Gerhardt, H., Dewerchin, M., Baes, M., De Bock, K., Ghesquière, B., Lunt, S.Y., Fendt, S.M. and Carmeliet, P.
Nature 520
(7546): 192-197.
9 April 2015
Mutational dynamics between primary and relapse neuroblastomas.
Schramm, A., Köster, J., Assenov, Y., Althoff, K., Peifer, M., Mahlow, E., Odersky, A., Beisser, D., Ernst, C., Henssen, A.G., Stephan, H., Schröder, C., Heukamp, L., Engesser, A., Kahlert, Y., Theissen, J., Hero, B., Roels, F., Altmüller, J., Nürnberg, P., Astrahantseff, K., Gloeckner, C., De Preter, K., Plass, C., Lee, S., Lode, H.N., Henrich, K.O., Gartlgruber, M., Speleman, F., Schmezer, P., Westermann, F., Rahmann, S., Fischer, M., Eggert, A. and Schulte, J.H.
Nature Genetics 47
(8): 872-877.
August 2015
The role of neutrophils in causing antineutrophil cytoplasmic autoantibody-associated vasculitis.
Schreiber, A. and Choi, M.
Current Opinion in Hematology 22
(1): 60-66.
January 2015
Phagocyte NADPH oxidase restrains the inflammasome in ANCA-induced GN.
Schreiber, A., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 26
(2): 411-424.
February 2015
Akutes Nierenversagen bei einem lebertransplantierten Patienten [Acute renal failure in a patient with a liver transplant].
Schreiber, A., Rudolph, B., Kahl, A. and Kettritz, R.
Nephrologe 10
(5): 416-418.
September 2015
The case : a 48-year-old man with pulmonary-renal syndrome.
Schreiber, A., Schindler, R., Adcock Funk, D.M. and Kahl, A.
Kidney International 87
(3): 667-668.
March 2015
CD177/NB1 receptor expression is dynamically regulated in sepsis patients.
Schreiber, A., Jannerjahn, A. and Kettritz, R.
Immunohematology 31
(3): 128-129.
2015
PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors.
Schrenk-Siemens, K., Wende, H., Prato, V., Song, K., Rostock, C., Loewer, A., Utikal, J., Lewin, G.R., Lechner, S.G. and Siemens, J.
Nature Neuroscience 18
(1): 10-16.
January 2015
Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway.
Schuchard, J., Winkler, M., Stölting, I., Schuster, F., Vogt, F.M., Barkhausen, J., Thorns, C., Santos, R.A., Bader, M. and Raasch, W.
British Journal of Pharmacology 172
(15): 3764-3778.
August 2015
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.
Schuijers, J., Junker, J.P., Mokry, M., Hatzis, P., Koo, B.K., Sasselli, V., van der Flier, L.G., Cuppen, E., van Oudenaarden, A. and Clevers, H.
Cell Stem Cell 16
(2): 158-170.
5 February 2015
Cognitive function in patients with primary adrenal insufficiency (Addison's disease).
Schultebraucks, K., Wingenfeld, K., Heimes, J., Quinkler, M. and Otte, C.
Psychoneuroendocrinology 55
: 1-7.
May 2015
Positionspapier Kardiovaskulaere Erkrankungen: Gendiagnostik bei kardiovaskulaeren Erkrankungen [Position paper of cardiovascular disease : genetic diagnostics in cardiovascular diseases].
Schulze-Bahr, E., Klaassen, S., Abdul-Khaliq, H. and Schunkert, H.
Deutsche Medizinische Wochenschrift 140
(20): 1538.
October 2015
Gendiagnostik bei kardiovaskulären Erkrankungen: Positionspapier der Deutschen Gesellschaft für Kardiologie (DGK) und der Deutschen Gesellschaft für Pädiatrische Kardiologie (DGPK) [Molecular diagnostics of cardiovascular diseases: Expert consensus statement by the German Cardiac Society (DGK) and the German Society of Pediatric Cardiology (DGPK)].
Schulze-Bahr, E., Klaassen, S., Abdul-Khaliq, H. and Schunkert, H.
Kardiologe 9
(3): 213-243.
June 2015
Die Reise vom Phaenotyp zum Genotyp : ein Blick hinter die Kulissen einer monogenen Form der Hypertonie [From phenotype to genotype : a glimpse behind the scenes of an unending story].
Schuster, H., Bähring, S., Wienker, T.F. and Luft, F.C.
Deutsche Medizinische Wochenschrift 140
(25): 1920-1923.
December 2015
Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2.
Schwarz, F., Karadeniz, Z., Fischer-Rosinsky, A., Willmes, D.M., Spranger, J. and Birkenfeld, A.L.
Aging 7
(8): 553-567.
August 2015
Changes in postural syntax characterize sensory modulation and natural variation of C. elegans locomotion.
Schwarz, R.F., Branicky, R., Grundy, L.J., Schafer, W.R. and Brown, A.E.X.
PLoS Computational Biology 11
(8): e1004322.
21 August 2015
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.
Schwarz, R.F., Ng, C.K.Y., Cooke, S.L., Newman, S., Temple, J., Piskorz, A.M., Gale, D., Sayal, K., Murtaza, M., Baldwin, P.J., Rosenfeld, N., Earl, H.M., Sala, E., Jimenez-Linan, M., Parkinson, C.A., Markowetz, F. and Brenton, J.D.
PLoS Medicine 12
(2): e1001789.
24 February 2015
Screening for small molecule disruptors of AKAP-PKA interactions.
Schächterle, C., Christian, F., Fernandes, J.M.P. and Klussmann, E.
Methods in Molecular Biology 1294
: 151-166.
2 March 2015
Chromatin dynamics during differentiation of myeloid cells.
Schönheit, J., Leutz, A. and Rosenbauer, F.
Journal of Molecular Biology 427
(3): 670-687.
13 February 2015
The effect of ICD programming on inappropriate and appropriate ICD Therapies in ischemic and nonischemic cardiomyopathy: the MADIT-RIT trial.
Sedláček, K., Ruwald, A.C., Kutyifa, V., McNitt, S., Thomsen, P.E.B., Klein, H., Stockburger, M., Wichterle, D., Merkely, B., de la Concha, J.F., Swissa, M., Zareba, W., Moss, A.J., Kautzner, J. and Ruwald, M.H.
Journal of Cardiovascular Electrophysiology 26
(4): 424-433.
April 2015
Disialoganglioside-specific human natural killer cells are effective against drug-resistant neuroblastoma.
Seidel, D., Shibina, A., Siebert, N., Wels, W.S., Reynolds, C.P., Huebener, N. and Lode, H.N.
Cancer Immunology Immunotherapy 64
(5): 621-634.
May 2015
Complex vasoactivity of liraglutide. Contribution of three gasotransmitters.
Selley, E., Molnar, G.A., Kun, S., Szijártó, I.A., Laczy, B., Kovacs, T., Fueloep, F. and Wittmann, I.
Artery Research 11
: 1-9.
September 2015
Phosphorylation of PACSIN2 by protein kinase C triggers the removal of caveolae from the plasma membrane.
Senju, Y., Rosenbaum, E., Shah, C., Hamada-Nakahara, S., Itoh, Y., Yamamoto, K., Hanawa-Suetsugu, K., Daumke, O. and Suetsugu, S.
Journal of Cell Science 128
(15): 2766-2780.
1 August 2015
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Serra, H., Chivite, I., Angulo-Urarte, A., Soler, A., Sutherland, J.D., Arruabarrena-Aristorena, A., Ragab, A., Lim, R., Malumbres, M., Fruttiger, M., Potente, M., Serrano, M., Fabra, A., Vinals, F., Casanovas, O., Pandolfi, P.P., Bigas, A., Carracedo, A., Gerhardt, H. and Graupera, M.
Nature Communications 6
: 7935.
31 July 2015
Molecular contacts of ribose-phosphate backbone of mRNA with human ribosome.
Sharifulin, D.E., Grosheva, A.S., Bartuli, Y.S., Malygin, A.A., Meschaninova, M.I., Ven'yaminova, A.G., Stahl, J., Graifer, D.M. and Karpova, G.G.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1849
(8): 930-939.
August 2015
Multiple sources of infection and potential endemic characteristics of the large outbreak of dengue in Guangdong in 2014.
Shen, S.Q., Wei, H.X., Fu, Y.H., Zhang, H., Mo, Q.Y., Wang, X.J., Deng, S.Q., Zhao, W., Liu, Y., Feng, X.S., Chen, W. and Peng, H.J.
Scientific Reports 5
: 16913.
23 November 2015
Operon structure and cotranslational subunit association direct protein assembly in bacteria.
Shieh, Y.W., Minguez, P., Bork, P., Auburger, J.J., Guilbride, D.L., Kramer, G. and Bukau, B.
Science 350
(6261): 678-680.
6 November 2015
Comparison of inter- and intraspecies variation in humans and fruit flies.
Shih, J., Hodge, R. and Andrade-Navarro, M.A.
Genomics Data 3
: 49-54.
March 2015
A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells.
Shih, H.P., Seymour, P.A., Patel, N.A., Xie, R., Wang, A., Liu, P.P., Yeo, G.W., Magnuson, M.A. and Sander, M.
Cell Reports 13
(2): 326-36.
13 October 2015
Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: Complete protection of rhesus monkeys from mucosal SHIV challenge.
Sholukh, A.M., Watkins, J.D., Vyas, H.K., Gupta, S., Lakhashe, S.K., Thorat, S., Zhou, M., Hemashettar, G., Bachler, B.C., Forthal, D.N., Villinger, F., Sattentau, Q.J., Weiss, R.A., Agatic, G., Corti, D., Lanzavecchia, A., Heeney, J.L. and Ruprecht, R.M.
Vaccine 33
(17): 2086-95.
21 April 2015
Waddington's Valleys and Captain Cook's Islands.
Sieweke, M.H.
Cell Stem Cell 16
(1): 7-8.
8 January 2015
FRET based ratiometric Ca(2+) imaging to investigate immune-mediated neuronal and axonal damage processes in experimental autoimmune encephalomyelitis.
Siffrin, V., Birkenstock, J., Luchtmann, D.W., Gollan, R., Baumgart, J., Niesner, R.A., Griesbeck, O. and Zipp, F.
Journal of Neuroscience Methods 249
: 8-15.
15 July 2015
Helicobacter pylori activates and expands Lgr5(+) stem cells through direct colonization of the gastric glands.
Sigal, M., Rothenberg, M.E., Logan, C.Y., Lee, J.Y., Honaker, R.W., Cooper, R.L., Passarelli, B., Camorlinga, M., Bouley, D.M., Alvarez, G., Nusse, R., Torres, J. and Amieva, M.R.
Gastroenterology 148
(7): 1392-1404.
June 2015
PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology.
Simandi, Z., Czipa, E., Horvath, A., Koszeghy, A., Bordas, C., Póliska, S., Juhász, I., Imre, L., Szabó, G., Dezso, B., Barta, E., Sauer, S., Karolyi, K., Kovacs, I., Hutóczki, G., Bognár, L., Klekner, A., Szucs, P., Bálint, B.L. and Nagy, L.
Stem Cells 33
(3): 726-741.
March 2015
Evolution of the immune system in humans from infancy to old age.
Simon, A.K., Hollander, G.A. and McMichael, A.
Proceedings of the Royal Society of London Series B-Biological Sciences 282
(1821): 20143085.
22 December 2015
Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management.
Sinnecker, T., Kuchling, J., Dusek, P., Dörr, J., Niendorf, T., Paul, F. and Wuerfel, J.
EPMA Journal 6
(1): 16.
27 August 2015
Optic radiation damage in multiple sclerosis is associated with visual dysfunction and retinal thinning - an ultrahigh-field MR pilot study.
Sinnecker, T., Oberwahrenbrock, T., Metz, I., Zimmermann, H., Pfueller, C.F., Harms, L., Ruprecht, K., Ramien, C., Hahn, K., Brück, W., Niendorf, T., Paul, F., Brandt, A.U., Dörr, J. and Wuerfel, J.
European Radiology 25
(1): 122-131.
January 2015
7T MRI in natalizumab-associated PML and ongoing MS disease activity: a case study.
Sinnecker, T., Othman, J., Kühl, M., Mekle, R., Selbig, I., Niendorf, T., Kunkel, A., Wienecke, P., Kern, P., Paul, F., Faiss, J. and Wuerfel, J.
Neurology Neuroimmunology & Neuroinflammation 2
(6): e171.
December 2015
Placental fractalkine is up-regulated in severe early-onset preeclampsia.
Siwetz, M., Dieber-Rotheneder, M., Cervar-Zivkovic, M., Kummer, D., Kremshofer, J., Weiss, G., Herse, F., Huppertz, B. and Gauster, M.
American Journal of Pathology 185
(5): 1334-1343.
May 2015
Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast.
Siwetz, M., Sundl, M., Kolb, D., Hiden, U., Herse, F., Huppertz, B. and Gauster, M.
Histochemistry and Cell Biology 143
(6): 565-574.
June 2015
Nuclear accessibility of β-actin mRNA is measured by 3D single-molecule real-time tracking.
Smith, C.S., Preibisch, S., Joseph, A., Abrahamsson, S., Rieger, B., Myers, E., Singer, R.H. and Grunwald, D.
Journal of Cell Biology 209
(4): 609-619.
25 May 2015
A gene regulatory program for meiotic prophase in the fetal ovary.
Soh, Y.Q.S., Junker, J.P., Gill, M.E., Mueller, J.L., van Oudenaarden, A. and Page, D.C.
PLoS Genetics 11
(9): e1005531.
17 September 2015
Simply the right time to turn on insulin.
Spagnoli, F.M.
EMBO Journal 34
(13): 1740-1742.
2 July 2015
Frequency and phenotypic spectrum of germline mutations in POLE and seven other polymerase genes in 266 patients with colorectal adenomas and carcinomas.
Spier, I., Holzapfel, S., Altmüller, J., Zhao, B., Horpaopan, S., Vogt, S., Chen, S., Morak, M., Raeder, S., Kayser, K., Stienen, D., Adam, R., Nürnberg, P., Plotz, G., Holinski-Feder, E., Lifton, R.P., Thiele, H., Hoffmann, P., Steinke, V. and Aretz, S.
International Journal of Cancer 137
(2): 320-331.
15 July 2015
Platelets play differential role during the initiation and progression of autoimmune neuroinflammation.
Starossom, S.C., Veremeyko, T., Yung, A.W.Y., Dukhinova, M., Au, C., Lau, A.Y., Weiner, H.L. and Ponomarev, E.D.
Circulation Research 117
(9): 779-792.
9 October 2015
Toxoplasma gondii seropositivity is negatively associated with multiple sclerosis.
Stascheit, F., Paul, F., Harms, L. and Rosche, B.
Journal of Neuroimmunology 285
: 119-124.
15 August 2015
Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum.
Staudacher, J.J., Naarmann-de Vries, I.S., Ujvari, S.J., Klinger, B., Kasim, M., Benko, E., Ostareck-Lederer, A., Ostareck, D.H., Bondke Persson, A., Lorenzen, S., Meier, J.C., Blüthgen, N., Persson, P.B., Henrion-Caude, A., Mrowka, R. and Faehling, M.
Nucleic Acids Research 43
(6): 3219-3236.
31 March 2015
CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes.
Steckelberg, A.L., Altmueller, J., Dieterich, C. and Gehring, N.H.
Nucleic Acids Research 43
(9): 4687-4700.
19 May 2015
Cell differentiation mediated by co-culture of human umbilical cord blood stem cells with murine hepatic cells.
Stecklum, M., Wulf-Goldenberg, A., Purfürst, B., Siegert, A., Keil, M., Eckert, K. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 51
(2): 183-191.
February 2015
Targeting of MYCN by means of DNA vaccination is effective against neuroblastoma in mice.
Stermann, A., Huebener, N., Seidel, D., Fest, S., Eschenburg, G., Stauder, M., Schramm, A., Eggert, A. and Lode, H.N.
Cancer Immunology Immunotherapy 64
(10): 1215-1227.
October 2015
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway.
Stincone, A., Prigione, A., Cramer, T., Wamelink, M.M.C., Campbell, K., Cheung, E., Olin-Sandoval, V., Gruening, N.M., Krueger, A., Tauqeer Alam, M., Keller, M.A., Breitenbach, M., Brindle, K.M., Rabinowitz, J.D. and Ralser, M.
Biological Reviews 90
(3): 927-963.
August 2015
Long-term clinical effects of ventricular pacing reduction with a changeover mode to minimize ventricular pacing in a general pacemaker population.
Stockburger, M., Boveda, S., Moreno, J., Da Costa, A., Hatala, R., Brachmann, J., Butter, C., Garcia Seara, J., Rolando, M. and Defaye, P.
European Heart Journal 36
(3): 151-157.
14 January 2015
Time-dependent risk reduction of ventricular tachyarrhythmias in cardiac resynchronization therapy patients: a MADIT-RIT sub-study.
Stockburger, M., Moss, A.J., Olshansky, B., Klein, H., McNitt, S., Schuger, C., Daubert, J.P., Goldenberg, I., Ruwald, A.C.H., Merkely, B., Zareba, W. and Kutyifa, V.
Europace 17
(7): 1085-1091.
July 2015
Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell lines.
Stolze, B., Reinhart, S., Bullinger, L., Fröhling, S. and Scholl, C.
Scientific Reports 5
: 8535.
23 February 2015
IFN-γ regulates CD8(+) memory T cell differentiation and survival in response to weak, but not strong, TCR signals.
Stoycheva, D., Deiser, K., Stärck, L., Nishanth, G., Schlüter, D., Uckert, W. and Schüler, T.
Journal of Immunology 194
(2): 553-559.
15 January 2015
Autophagy controls acquisition of aging features in macrophages.
Stranks, A.J., Hansen, A.L., Panse, I., Mortensen, M., Ferguson, D.J.P., Puleston, D.J., Shenderov, K., Watson, A.S., Veldhoen, M., Phadwal, K., Cerundolo, V. and Simon, A.K.
Journal of Innate Immunity 7
(4): 375-391.
June 2015
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke, M., Bounab, Y., Strempel, N., Klockmeier, K., Yigit, S., Friedrich, R.P., Chaurasia, G., Li, S., Hesse, F., Riechers, S.P., Russ, J., Nicoletti, C., Boeddrich, A., Wiglenda, T., Haenig, C., Schnoegl, S., Fournier, D., Graham, R.K., Hayden, M.R., Sigrist, S., Bates, G.P., Priller, J., Andrade-Navarro, M.A., Futschik, M.E. and Wanker, E.E.
Genome Research 25
(5): 701-713.
May 2015
hiCLIP reveals the in vivo atlas of mRNA secondary structures recognized by Staufen 1.
Sugimoto, Y., Vigilante, A., Darbo, E., Zirra, A., Militti, C., D'Ambrogio, A., Luscombe, N.M. and Ule, J.
Nature 519
(7544): 491-494.
26 March 2015
Quantification of LV function and mass by cardiovascular magnetic resonance: multi-center variability and consensus contours.
Suinesiaputra, A., Bluemke, D.A., Cowan, B.R., Friedrich, M.G., Kramer, C.M., Kwong, R., Plein, S., Schulz-Menger, J., Westenberg, J.J.M., Young, A.A. and Nagel, E.
Journal of Cardiovascular Magnetic Resonance 17
(1): 63.
28 July 2015
VH replacement in primary immunoglobulin repertoire diversification.
Sun, A., Novobrantseva, T.I., Coffre, M., Hewitt, S.L., Jensen, K., Skok, J.A., Rajewsky, K. and Koralov, S.B.
Proceedings of the National Academy of Sciences of the United States of America 112
(5): E458-E466.
3 February 2015
Structure and function of the global ocean microbiome.
Sunagawa, S., Coelho, L.P., Chaffron, S., Kultima, J.R., Labadie, K., Salazar, G., Djahanschiri, B., Zeller, G., Mende, D.R., Alberti, A., Cornejo-Castillo, F.M., Costea, P.I., Cruaud, C., d'Ovidio, F., Engelen, S., Ferrera, I., Gasol, J.M., Guidi, L., Hildebrand, F., Kokoszka, F., Lepoivre, C., Lima-Mendez, G., Poulain, J., Poulos, B.T., Royo-Llonch, M., Sarmento, H., Vieira-Silva, S., Dimier, C., Picheral, M., Searson, S., Kandels-Lewis, S., Bowler, C., de Vargas, C., Gorsky, G., Grimsley, N., Hingamp, P., Iudicone, D., Jaillon, O., Not, F., Ogata, H., Pesant, S., Speich, S., Stemmann, L., Sullivan, M.B., Weissenbach, J., Wincker, P., Karsenti, E., Raes, J., Acinas, S.G. and Bork, P.
Science 348
(6237): 1261359.
22 May 2015
Computational eco-systems biology in Tara Oceans: translating data into knowledge.
Sunagawa, S., Karsenti, E., Bowler, C. and Bork, P.
Molecular Systems Biology 11
(5): 809.
21 May 2015
Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.
Sury, M.D., McShane, E., Hernandez-Miranda, L.R., Birchmeier, C. and Selbach, M.
Molecular & Cellular Proteomics 14
(1): 50-65.
1 January 2015
Deep, quantitative coverage of the lysine acetylome using novel anti-acetyl-lysine antibodies and an optimized proteomic workflow.
Svinkina, T., Gu, H., Silva, J.C., Mertins, P., Qiao, J., Fereshetian, S., Jaffe, J.D., Kuhn, E., Udeshi, N.D. and Carr, S.A.
Molecular & Cellular Proteomics 14
(9): 2429-2440.
1 September 2015
STRING v10: protein-protein interaction networks, integrated over the tree of life.
Szklarczyk, D., Franceschini, A., Wyder, S., Forslund, K., Heller, D., Huerta-Cepas, J., Simonovic, M., Roth, A., Santos, A., Tsafou, K.P., Kuhn, M., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 43
(D1): D447-D452.
January 2015
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.
Szulzewsky, F., Pelz, A., Feng, X., Synowitz, M., Markovic, D., Langmann, T., Holtman, I.R., Wang, X., Eggen, B.J.L., Boddeke, H.W.G.M., Hambardzumyan, D., Wolf, S.A. and Kettenmann, H.
PLoS ONE 10
(2): e0116644.
6 February 2015
Cytoskeletal components define protein location to membrane microdomains.
Szymanski, W.G., Zauber, H., Erban, A., Wu, X.N. and Schulze, W.X.
Molecular & Cellular Proteomics 14
(9): 2493-2509.
September 2015
T
Anatomical organization and spatiotemporal firing patterns of layer 3 neurons in the rat medial entorhinal cortex.
Tang, Q., Ebbesen, C.L., Sanguinetti-Scheck, J.I., Preston-Ferrer, P., Gundlfinger, A., Winterer, J., Beed, P., Ray, S., Naumann, R., Schmitz, D., Brecht, M. and Burgalossi, A.
Journal of Neuroscience 35
(36): 12346-12354.
9 September 2015
Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983.
Tanis, E., Julie, C., Emile, J.F., Mauer, M., Nordlinger, B., Aust, D., Roth, A., Lutz, M.P., Gruenberger, T., Wrba, F., Sorbye, H., Bechstein, W., Schlag, P., Fisseler, A. and Ruers, T.
European Journal of Cancer 51
(17): 2708-2717.
November 2015
miR-184 regulates pancreatic β-cell function according to glucose metabolism.
Tattikota, S.G., Rathjen, T., Hausser, J., Khedkar, A., Kabra, U.D., Pandey, V.K., Sury, M.D., Wessels, H.H., Mollet, I.G., Eliasson, L., Selbach, M., Zinzen, R.P., Zavolan, M., Kadener, S., Tschöp, M., Jastroch, M., Friedländer, M.R. and Poy, M.N.
Journal of Biological Chemistry 290
(33): 20284-20294.
14 August 2015
Disease evolution and outcomes in familial AML with germline CEBPA mutations.
Tawana, K., Wang, J., Renneville, A., Bödör, C., Hills, R., Loveday, C., Savic, A., Van Delft, F.W., Treleaven, J., Georgiades, P., Uglow, E., Asou, N., Uike, N., Debeljak, M., Jazbec, J., Ancliff, P., Gale, R., Thomas, X., Mialou, V., Döhner, K., Bullinger, L., Mueller, B., Pabst, T., Stelljes, M., Schlegelberger, B., Wozniak, E., Iqbal, S., Okosun, J., Araf, S., Frank, A.K., Lauridsen, F.B., Porse, B., Nerlov, C., Owen, C., Dokal, I., Gribben, J., Smith, M., Preudhomme, C., Chelala, C., Cavenagh, J. and Fitzgibbon, J.
Blood 126
(10): 1214-1223.
3 September 2015
Treatment of multiple sclerosis - relationship between vitamin d and interferon β-1b.
Taylor, B., Moses, H., Paul, F., Suarez, G. and Rametta, M.
European Neurological Review 10
(2): 124-130.
2015
Postnatal β-cell proliferation and mass expansion is dependent on the transcription factor Nkx6.1.
Taylor, B.L., Benthuysen, J. and Sander, M.
Diabetes 64
(3): 897-903.
1 March 2015
How perifosine affects liposome-encapsulated drug delivery across a cell barrier.
Testen, A, Podlipec, R, Mravljak, J, Orthmann, A, Sentjurc, M, Zeisig, R, Strancar, J and Koklic, T
Therapeutic Delivery 6
(4): 423-441.
April 2015
A multiplexed NMR-reporter approach to measure cellular kinase and phosphatase activities in real-time.
Thongwichian, R., Kosten, J., Benary, U., Rose, H.M., Stuiver, M., Theillet, F.X., Dose, A., Koch, B., Yokoyama, H., Schwarzer, D., Wolf, J. and Selenko, P.
Journal of the American Chemical Society 137
(20): 6468-6471.
27 May 2015
Transposon-based, targeted ex vivo gene therapy to treat age-related macular degeneration (TargetAMD).
Thumann, G., Perdikomati-Dahmen, M., Izsvák, Z., Ivics, Z., Garcia Layana, A., Ronchetti, M., Petrovski, G., Scherman, D., Aranda, P., Pouillot, S., Binder, S., Johnen, S. and van den Berg, J.
Human Gene Therapy Clinical Development 26
(2): 97-100.
18 June 2015
Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus.
Thélie, A., Desiderio, S., Hanotel, J., Quigley, I., Van Driessche, B., Rodari, A., Borromeo, M.D., Kricha, S., Lahaye, F., Croce, J., Cerda-Moya, G., Ordoño Fernandez, J., Bolle, B., Lewis, K.E., Sander, M., Pierani, A., Schubert, M., Johnson, J.E., Kintner, C.R., Pieler, T., Van Lint, C., Henningfeld, K.A., Bellefroid, E.J. and Van Campenhout, C.
Development 142
(19): 3416-28.
1 October 2015
Cavin 1 function does not follow caveolar morphology.
Timmel, T., Kunz, S., Seifert, F., Schuelke, M. and Spuler, S.
American Journal of Physiology Cell Physiology 308
(12): C1023-C1030.
15 June 2015
Clinical effects of phosphodiesterase 3A mutations in inherited hypertension with brachydactyly.
Toka, O., Tank, J., Schächterle, C., Aydin, A., Maass, P.G., Elitok, S., Bartels-Klein, E., Hollfinger, I., Lindschau, C., Mai, K., Boschmann, M., Rahn, G., Movsesian, M.A., Müller, T., Doescher, A., Gnoth, S., Mühl, A., Toka, H.R., Wefeld-Neuenfeld, Y., Utz, W., Töpper, A., Jordan, J., Schulz-Menger, J., Klussmann, E., Bähring, S. and Luft, F.C.
Hypertension 66
(4): 800-808.
October 2015
DULIP: A dual luminescence-based co-immunoprecipitation assay for interactome mapping in mammalian cells.
Trepte, P., Buntru, A., Klockmeier, K., Willmore, L., Arumughan, A., Secker, C., Zenkner, M., Brusendorf, L., Rau, K., Redel, A. and Wanker, E.E.
Journal of Molecular Biology 427
(21): 3375-3388.
23 October 2015
Ultrastructural changes associated with myocardial apoptosis, in failing rat hearts induced by volume overload.
Treskatsch, S., Shakibaei, M., Feldheiser, A., Shaqura, M., Dehe, L., Roepke, T.K., Spies, C., Schaefer, M. and Mousa, S.A.
International Journal of Cardiology 197
: 327-332.
15 October 2015
Upregulation of the kappa opioidergic system in left ventricular rat myocardium in response to volume overload : adaptive changes of the cardiac kappa opioid system in heart failure.
Treskatsch, S., Shaqura, M., Dehe, L., Feldheiser, A., Roepke, T.K., Shakibaei, M., Spies, C.D., Schäfer, M. and Mousa, S.A.
Pharmacological Research 102
: 33-41.
December 2015
Effects of a new combination of nutraceuticals with Morus alba on lipid profile, insulin sensitivity and endotelial function in dyslipidemic subjects. A cross-over, randomized, double-blind trial.
Trimarco, V., Izzo, R., Stabile, E., Rozza, F., Santoro, M., Manzi, M.V., Serino, F., Schiattarella, G.G., Esposito, G. and Trimarco, B.
High Blood Pressure & Cardiovascular Prevention 22
(2): 149-154.
June 2015
Development of an intein-mediated split-Cas9 system for gene therapy.
Truong, D.J.J., Kühner, K., Kühn, R., Werfel, S., Engelhardt, S., Wurst, W. and Ortiz, O.
Nucleic Acids Research 43
(13): 6450-6458.
27 July 2015
Diabetes mellitus and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition.
Tsilidis, K.K., Allen, N.E., Appleby, P.N., Rohrmann, S., Nöthlings, U., Arriola, L., Gunter, M.J., Chajes, V., Rinaldi, S., Romieu, I., Murphy, N., Riboli, E., Tzoulaki, I., Kaaks, R., Lukanova, A., Boeing, H., Pischon, T., Dahm, C.C., Overvad, K., Quirós, J.R., Fonseca-Nunes, A., Molina-Montes, E., Gavrila Chervase, D., Ardanaz, E., Khaw, K.T., Wareham, N.J., Roswall, N., Tjønneland, A., Lagiou, P., Trichopoulos, D., Trichopoulou, A., Palli, D., Pala, V., Tumino, R., Vineis, P., Bueno-de-Mesquita, H.B., Malm, J., Orho-Melander, M., Johansson, M., Stattin, P., Travis, R.C. and Key, T.J.
International Journal of Cancer 136
(2): 372-381.
15 January 2015
The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis.
Tuorto, F., Herbst, F., Alerasool, N., Bender, S., Popp, O., Federico, G., Reitter, S., Liebers, R., Stoecklin, G., Groene, H.J., Dittmar, G., Glimm, H. and Lyko, F.
EMBO Journal 34
(18): 2350-2362.
14 September 2015
U
Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a negative tumors.
Ueberham, E., Glöckner, P., Göhler, C., Straub, B.K., Teupser, D., Schönig, K., Braeuning, A., Höhn, A.K., Jerchow, B., Birchmeier, W., Gaunitz, F., Arendt, T., Sansom, O., Gebhardt, R. and Ueberham, U.
Molecular Cancer Research 13
(2): 239-249.
February 2015
The IL-15 cytokine system provides growth and survival signals in hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells.
Ullrich, K., Blumenthal-Barby, F., Lamprecht, B., Koechert, K., Lenze, D., Hummel, M., Mathas, S., Doerken, B. and Janz, M.
Leukemia 29
(5): 1213-1218.
May 2015
V
In vivo evidence for lysosome depletion and impaired autophagic clearance in hereditary spastic paraplegia type SPG11.
Varga, R.E., Khundadze, M., Damme, M., Nietzsche, S., Hoffmann, B., Stauber, T., Koch, N., Hennings, J.C., Franzka, P., Huebner, A.K., Kessels, M.M., Biskup, C., Jentsch, T.J., Qualmann, B., Braulke, T., Kurth, I., Beetz, C. and Hübner, C.A.
PLoS Genetics 11
(8): e1005454.
18 August 2015
Periodic limb movements during REM sleep in multiple sclerosis: a previously undescribed entity.
Veauthier, C., Gaede, G., Radbruch, H., Sieb, J.P., Wernecke, K.D. and Paul, F.
Neuropsychiatric Disease and Treatment 11
: 2323-2329.
9 September 2015
Sleep disorders reduce health-related quality of life in multiple sclerosis (Nottingham Health Profile data in patients with multiple sclerosis).
Veauthier, C., Gaede, G., Radbruch, H., Wernecke, K.D. and Paul, F.
International Journal of Molecular Sciences 16
(7): 16514-16528.
21 July 2015
A multiscale computational model of spatially resolved calcium cycling in cardiac myocytes: from detailed cleft dynamics to the whole cell concentration profiles.
Vierheller, J., Neubert, W., Falcke, M., Gilbert, S.H. and Chamakuri, N.
Frontiers in Physiology 6
: 255.
24 September 2015
Environmental characteristics of Agulhas rings affect interocean plankton transport.
Villar, E., Farrant, G.K., Follows, M., Garczarek, L., Speich, S., Audic, S., Bittner, L., Blanke, B., Brum, J.R., Brunet, C., Casotti, R., Chase, A., Dolan, J.R., d'Ortenzio, F., Gattuso, J.P., Grima, N., Guidi, L., Hill, C.N., Jahn, O., Jamet, J.L., Le Goff, H., Lepoivre, C., Malviya, S., Pelletier, E., Romagnan, J.B., Roux, S., Santini, S., Scalco, E., Schwenck, S.M., Tanaka, A., Testor, P., Vannier, T., Vincent, F., Zingone, A., Dimier, C., Picheral, M., Searson, S., Kandels-Lewis, S., Acinas, S.G., Bork, P., Boss, E., de Vargas, C., Gorsky, G., Ogata, H., Pesant, S., Sullivan, M.B., Sunagawa, S., Wincker, P., Karsenti, E., Bowler, C., Not, F., Hingamp, P. and Iudicone, D.
Science 348
(6237): 1261447.
22 May 2015
Angiotensin type 2 receptor (AT2R) and receptor Mas: a complex liaison.
Villela, D., Leonhardt, J., Patel, N., Joseph, J., Kirsch, S., Hallberg, A., Unger, T., Bader, M., Santos, R.A., Sumners, C. and Steckelings, U.M.
Clinical Science 128
(4): 227-234.
1 February 2015
Effects of diazoxide in multiple sclerosis: a randomized, double-blind phase 2 clinical trial.
Villoslada, P., Rovira, A., Montalban, X., Arroyo, R., Paul, F., Meca-Lallana, V., Ramo, C., Fernandez, O., Saiz, A., Garcia-Merino, A., Ramió-Torrentà, L., Casanova, B., Oreja-Guevara, C., Muñoz, D., Martinez-Rodriguez, J.E., Lensch, E., Prieto, J.M., Meuth, S.G., Nuñez, X., Campás, C. and Pugliese, M.
Neurology Neuroimmunology & Neuroinflammation 2
(5): e147.
October 2015
Mutations in TBX18 cause dominant urinary tract malformations via transcriptional dysregulation of ureter development.
Vivante, Asaf, Kleppa, M.J., Schulz, J., Kohl, S., Sharma, A., Chen, J., Shril, S., Hwang, D.Y., Weiss, A.C., Kaminski, M.M., Shukrun, R., Kemper, M.J., Lehnhardt, A., Beetz, R., Sanna-Cherchi, S., Verbitsky, M., Gharavi, A.G., Stuart, H.M., Feather, S.A., Goodship, J.A., Goodship, T.H.J., Woolf, A.S., Westra, S.J., Doody, D.P., Bauer, S.B., Lee, R.S., Adam, R.M., Lu, W., Reutter, H.M., Kehinde, E.O., Mancini, E.J., Lifton, R.P., Tasic, V., Lienkamp, S.S., Jüppner, H., Kispert, A. and Hildebrandt, F.
American Journal of Human Genetics 97
(2): 291-301.
6 August 2015
Temporal and technical variability of human gut metagenomes.
Voigt, A.Y., Costea, P.I., Kultima, J.R., Li, S.S., Zeller, G., Sunagawa, S. and Bork, P.
Genome Biology 16
(1): 73.
8 April 2015
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Volk, T., Pannicke, U., Reisli, I., Bulashevska, A., Ritter, J., Björkman, A., Schäffer, A.A., Fliegauf, M., Sayar, E.H., Salzer, U., Fisch, P., Pfeifer, D., Di Virgilio, M., Cao, H., Yang, F., Zimmermann, K., Keles, S., Caliskaner, Z., Güner, S.Ü., Schindler, D., Hammarström, L., Rizzi, M., Hummel, M., Pan-Hammarstroem, Q., Schwarz, K. and Grimbacher, B.
Human Molecular Genetics 24
(25): 7361-7372.
20 December 2015
Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage.
Vos, S.J.B., Verhey, F., Froelich, L., Kornhuber, J., Wiltfang, J., Maier, W., Peters, O., Ruether, E., Nobili, F., Morbelli, S., Frisoni, G.B., Drzezga, A., Didic, M., van Berckel, B.N.M., Simmons, A., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Muscio, C., Herukka, S.K., Salmon, E., Bastin, C., Wallin, A., Nordlund, A., de Mendonca, A., Silva, D., Santana, I., Lemos, R., Engelborghs, S., Van der Mussele, S., Freund-Levi, Y., Wallin, A.K., Hampel, H., van der Flier, W., Scheltens, P. and Visser, P.J.
Brain 138
(Pt 5): 1327-1338.
May 2015
Ectodysplasin/NF-κB promotes mammary cell fate via Wnt/β-catenin pathway.
Voutilainen, M., Lindfors, P.H., Trela, E., Loennblad, D., Shirokova, V., Elo, T., Rysti, E., Schmidt-Ullrich, R., Schneider, P. and Mikkola, M.L.
PLoS Genetics 11
(11): e1005676.
18 November 2015
A MYC-driven change in mitochondrial dynamics limits YAP/TAZ function in mammary epithelial cells and breast cancer.
von Eyss, B., Jaenicke, L.A., Kortlever, R.M., Royla, N., Wiese, K.E., Letschert, S., McDuffus, L.A., Sauer, M., Rosenwald, A., Evan, G.I., Kempa, S. and Eilers, M.
Cancer Cell 28
(6): 743-757.
14 December 2015
Advanced cardiovascular magnetic resonance techniques.
von Knobelsdorff-Brenkenhoff, F., Dieringer, M.A. and Schulz-Menger, J.
In:
Basic Principles of Cardiovascular MRI: Physics and Imaging Technique.
Springer, 315-325.
ISBN 978-3-319-22140-3
2015
W
Light-switched inhibitors of protein tyrosine phosphatase PTP1B based on phosphonocarbonyl phenylalanine as photoactive phosphotyrosine mimetic.
Wagner, S., Schütz, A. and Rademann, J.
Bioorganic and Medicinal Chemistry 23
(12): 2839-2847.
15 June 2015
Anchoring dipalmitoyl phosphoethanolamine to nanoparticles boosts cellular uptake and fluorine-19 magnetic resonance signal.
Waiczies, S., Lepore, S., Sydow, K., Drechsler, S., Ku, M.C., Martin, C., Lorenz, D., Schütz, I., Reimann, H.M., Purfürst, B., Dieringer, M.A., Waiczies, H., Dathe, M., Pohlmann, A. and Niendorf, T.
Scientific Reports 5
: 8427.
12 February 2015
A Grhl2-dependent gene network controls trophoblast branching morphogenesis.
Walentin, K., Hinze, C., Werth, M., Haase, N., Varma, S., Morell, R., Aue, A., Pötschke, E., Warburton, D., Qiu, A., Barasch, J., Purfürst, B., Dieterich, C., Popova, E., Bader, M., Dechend, R., Staff, A.C., Yurtdas, Z.Y., Kilic, E. and Schmidt-Ott, K.M.
Development 142
(6): 1125-1136.
15 March 2015
Stimulation of PPARα normalizes the skin lipid ratio and improves the skin barrier of normal and filaggrin deficient reconstructed skin.
Wallmeyer, L., Lehnen, D., Eger, N., Sochorová, M., Opálka, L., Kováčik, A., Vávrová, K. and Hedtrich, S.
Journal of Dermatological Science 80
(2): 102-10.
2 December 2015
MHCII-independent CD4(+) T cells protect injured CNS neurons via IL-4.
Walsh, J.T., Hendrix, S., Boato, F., Smirnov, I., Zheng, J., Lukens, J.R., Gadani, S., Hechler, D., Gölz, G., Rosenberger, K., Kammertöns, T., Vogt, J., Vogelaar, C., Siffrin, V., Radjavi, A., Fernandez-Castaneda, A., Gaultier, A., Gold, R., Kanneganti, T.D., Nitsch, R., Zipp, F. and Kipnis, J.
Journal of Clinical Investigation 125
(2): 699-714.
2 February 2015
Chemosensitization by diverging modulation by short-term and long-term TNF-α action on ABCB1 expression and NF-κB signaling in colon cancer.
Walther, W., Kobelt, D., Bauer, L., Aumann, J. and Stein, U.
International Journal of Oncology 47
(6): 2276-2285.
December 2015
Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates.
Wang, A., Yue, F., Li, Y., Xie, R., Harper, T., Patel, N.A., Muth, K., Palmer, J., Qiu, Y., Wang, J., Lam, D.K., Raum, J.C., Stoffers, D.A., Ren, B. and Sander, M.
Cell Stem Cell 16
(4): 386-99.
2 April 2015
De novo protein structure determination from near-atomic-resolution cryo-EM maps.
Wang, R.Y.R., Kudryashev, M., Li, X., Egelman, E.H., Basler, M., Cheng, Y., Baker, D. and DiMaio, F.
Nature Methods 12
(4): 335-338.
April 2015
Exercise during pregnancy protects adult mouse offspring from diet-induced obesity.
Wasinski, F., Bacurau, R.F.P., Estrela, G.R., Klempin, F., Arakaki, A.M., Batista, R.O., Mafra, F.F.P., do Nascimento, L.F.R., Hiyane, M.I., Velloso, L.A., Camara, N.O.S. and Araujo, R.C.
Nutrition & Metabolism 12
: 56.
18 December 2015
Myocarditis.
Wassmuth, R. and Schulz-Menger, J.
In:
Advanced Cardiac Imaging.
UNSPECIFIED, 439-458.
ISBN 978-1-78242-282-2
2015
Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.
Watson, A.S., Riffelmacher, T., Stranks, A., Williams, O., De Boer, J., Cain, K., MacFarlane, M., McGouran, J., Kessler, B., Khandwala, S., Chowdhury, O., Puleston, D., Phadwal, K., Mortensen, M., Ferguson, D., Soilleux, E., Woll, P., Jacobsen, S.E.W. and Simon, A.K.
Cell Death Discovery 1
: 15008.
17 August 2015
Wiring the vascular network with neural cues: a CNS perspective.
Waächli, T., Wacker, A., Frei, K., Regli, L., Schwab, M.E., Hoerstrup, S.P., Gerhardt, H. and Engelhardt, B.
Neuron 87
(2): 271-296.
15 July 2015
The carbomer-lecithin adjuvant Adjuplex has potent immunoactivating properties and elicits protective adaptive immunity against influenza virus challenge in mice.
Wegmann, F., Moghaddam, A.E., Schiffner, T., Gartlan, K.H., Powell, T.J., Russell, R.A., Baart, M., Carrow, E.W. and Sattentau, Q.J.
Clinical and Vaccine Immunology 22
(9): 1004-1012.
9 September 2015
Differential gene expression of human chondrocytes cultured under short-term altered gravity conditions during parabolic flight maneuvers.
Wehland, M., Aleshcheva, G., Schulz, H., Saar, K., Hübner, N., Hemmersbach, R., Braun, M., Ma, X., Frett, T., Warnke, E., Riwaldt, S., Pietsch, J., Corydon, T.J., Infanger, M. and Grimm, D.
Cell Communication and Signaling 13
(1): 18.
20 March 2015
Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species.
Weidner, C., Rousseau, M., Plauth, A., Wowro, S.J., Fischer, C., Abdel-Aziz, H. and Sauer, S.
Phytomedicine 22
(2): 262-270.
15 February 2015
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann, A., Grau, M., Erdmann, T., Merkel, O., Sobhiafshar, U., Anagnostopoulos, I., Hummel, M., Siegert, A., Hayford, C., Madle, H., Wollert-Wulf, B., Fichtner, I., Dörken, B., Dirnhofer, S., Mathas, S., Janz, M., Emre, N.C.T., Rosenwald, A., Ott, G., Lenz, P., Tzankov, A. and Lenz, G.
Blood 125
(1): 124-132.
1 January 2015
High-resolution chromatin dynamics during a yeast stress response.
Weiner, A., Hsieh, T.H.S., Appleboim, A., Chen, H.V., Rahat, A., Amit, I., Rando, O.J. and Friedman, N.
Molecular Cell 58
(2): 371-386.
16 April 2015
Accurate liability estimation improves power in ascertained case-control studies.
Weissbrod, O., Lippert, C., Geiger, D. and Heckerman, D.
Nature Methods 12
(4): 332-334.
April 2015
DAZL regulates Tet1 translation in murine embryonic stem cells.
Welling, M., Chen, H.H., Muñoz, J., Musheev, M.U., Kester, L., Junker, J.P., Mischerikow, N., Arbab, M., Kuijk, E., Silberstein, L., Kharchenko, P.V., Geens, M., Niehrs, C., van de Velde, H., van Oudenaarden, A., Heck, A.J. and Geijsen, N.
EMBO Reports 16
(7): 791-802.
July 2015
Cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids and their role in cardiovascular disease.
Westphal, C., Konkel, A. and Schunck, W.H.
Advances in Experimental Medicine and Biology 851
: 151-187.
2015
Impulse control in the dorsolateral prefrontal cortex counteracts post-diet weight regain in obesity.
Weygandt, M., Mai, K., Dommes, E., Ritter, K., Leupelt, V., Spranger, J. and Haynes, J.D.
NeuroImage 109
: 318-327.
1 April 2015
ω-3 PUFAs in the prevention and cure of inflammatory, degenerative, and neoplastic diseases 2014.
Weylandt, K.H., Chen, Y.Q., Lim, K., Su, H.M., Cittadini, A. and Calviello, G.
BioMed Research International 2015
: 695875.
2015
Omega-3 polyunsaturated fatty acids: the way forward in times of mixed evidence.
Weylandt, K.H., Serini, S., Chen, Y.Q., Su, H.M., Lim, K., Cittadini, A. and Calviello, G.
BioMed Research International 2015
: 143109.
2 August 2015
Bcl11a (Ctip1) controls migration of cortical projection neurons through regulation of Sema3c.
Wiegreffe, C., Simon, R., Peschkes, K., Kling, C., Strehle, M., Cheng, J., Srivatsa, S., Liu, P., Jenkins, N.A., Copeland, N.G., Tarabykin, V. and Britsch, S.
Neuron 87
(2): 311-325.
15 July 2015
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.
Willer, A., Jakobsen, J.S., Ohlsson, E., Rapin, N., Waage, J., Billing, M., Bullinger, L., Karlsson, S. and Porse, B.T.
Leukemia 29
(5): 1018-1031.
May 2015
Effects of mineralocorticoid receptor stimulation via fludrocortisone on memory in women with borderline personality disorder.
Wingenfeld, K., Kuehl, L.K., Janke, K., Hinkelmann, K., Eckert, F.C., Roepke, S. and Otte, C.
Neurobiology of Learning and Memory 120
: 94-100.
April 2015
Effect of current and lifetime posttraumatic stress disorder on 24-h urinary catecholamines and cortisol: results from the Mind Your Heart Study.
Wingenfeld, K., Whooley, M.A., Neylan, T.C., Otte, C. and Cohen, B.E.
Psychoneuroendocrinology 52
: 83-91.
February 2015
Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain.
Winkelmann, A., Semtner, M. and Meier, J.C.
Cell Death & Disease 6
: e1776.
4 June 2015
Identification of a new genomic hot spot of evolutionary diversification of protein function.
Winkelmann, A., You, X., Gruenewald, N., Haeussler, U., Krestel, H., Haas, C.A., Schwarz, G., Chen, W. and Meier, J.C.
PLoS ONE 10
(5): e0125413.
8 May 2015
Striatal infarction elicits secondary extrafocal MRI changes in ipsilateral substantia nigra.
Winter, B., Brunecker, P., Fiebach, J.B., Jungehulsing, G.J., Kronenberg, G. and Endres, M.
PLoS ONE 10
(9): e0136483.
1 September 2015
Thermal magnetic resonance: physics considerations and electromagnetic field simulations up to 23.5 Tesla (1GHz).
Winter, L., Oezerdem, C., Hoffmann, W., van de Lindt, T., Periquito, J., Ji, Y., Ghadjar, P., Budach, V., Wust, P. and Niendorf, T.
Radiation Oncology 10
(1): 201.
22 September 2015
On the RF heating of coronary stents at 7.0 Tesla MRI.
Winter, L., Oberacker, E., Özerdem, C., Ji, Y., von Knobelsdorff-Brenkenhoff, F., Weidemann, G., Ittermann, B., Seifert, F. and Niendorf, T.
Magnetic Resonance in Medicine 74
(4): 999-1010.
October 2015
Amino acids, lipid metabolites, and ferritin as potential mediators linking red meat consumption to type 2 diabetes.
Wittenbecher, C., Mühlenbruch, K., Kröger, J., Jacobs, S., Kuxhaus, O., Floegel, A., Fritsche, A., Pischon, T., Prehn, C., Adamski, J., Joost, H.G., Boeing, H. and Schulze, M.B.
American Journal of Clinical Nutrition 101
(6): 1241-1250.
June 2015
Development of a high-resolution NGS-based HLA-typing and analysis pipeline.
Wittig, M., Anmarkrud, J.A., Kässens, J.C., Koch, S., Forster, M., Ellinghaus, E., Hov, J.R., Sauer, S., Schimmler, M., Ziemann, M., Görg, S., Jacob, F., Karlsen, T.H. and Franke, A.
Nucleic Acids Research 43
(11): e70.
23 June 2015
Interactions of hyaluronic acid with the skin and implications for the dermal delivery of biomacromolecules.
Witting, M., Boreham, A., Brodwolf, R., Vávrová, K., Alexiev, U., Friess, W. and Hedtrich, S.
Molecular Pharmaceutics 12
(5): 1391-1401.
4 May 2015
Thermosensitive dendritic polyglycerol-based nanogels for cutaneous delivery of biomacromolecules.
Witting, M., Molina, M., Obst, K., Plank, R., Eckl, K.M., Hennies, H.C., Calderón, M., Friess, W. and Hedtrich, S.
Nanomedicine: Nanotechnology, Biology and Medicine 11
(5): 1179-87.
July 2015
Recent advances in topical delivery of proteins and peptides mediated by soft matter nanocarriers.
Witting, M., Obst, K., Friess, W. and Hedtrich, S.
Biotechnology Advances 33
(6 Pt 3): 1355-1369.
1 November 2015
Feasibility study for intraepidermal delivery of proteins using a solid microneedle array.
Witting, M., Obst, K., Pietzsch, M., Friess, W. and Hedtrich, S.
International Journal of Pharmaceutics 486
(1-2): 52-58.
30 May 2015
Analysis of impedance-based cellular growth assays.
Witzel, F., Fritsche-Guenther, R., Lehmann, N., Sieber, A. and Blüthgen, N.
Bioinformatics 31
(16): 2705-2712.
15 August 2015
The green tea polyphenol (-)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios.
Wobst, H.J., Sharma, A., Diamond, M.I., Wanker, E.E. and Bieschke, J.
FEBS Letters 589
(1): 77-83.
2 January 2015
Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI.
Wolfsgruber, S., Jessen, F., Koppara, A., Kleineidam, L., Schmidtke, K., Froelich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F.M., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Pantel, J., Rienhoff, O., Ruether, E., Henn, F., Wiltfang, J., Maier, W., Kornhuber, J. and Wagner, M.
Neurology 84
(12): 1261-1268.
24 March 2015
Identification of the GTPase-activating protein DEP domain containing 1B (DEPDC1B) as a transcriptional target of Pitx2.
Wu, D., Zhu, X., Jimenez-Cowell, K., Mold, A.J., Sollecito, C.C., Lombana, N., Jiao, M. and Wei, Q.
Experimental Cell Research 333
(1): 80-92.
10 April 2015
Syntaxin 1B is important for mouse postnatal survival and proper synaptic function at the mouse neuromuscular junctions.
Wu, Y.J., Tejero, R., Arancillo, M., Vardar, G., Korotkova, T., Kintscher, M., Schmitz, D., Ponomarenko, A., Tabares, L. and Rosenmund, C.
Journal of Neurophysiology 114
(4): 2404-2417.
1 October 2015
Die Hirnforscherin Elisabeth Beck (1907-2002) Aus Deutschland vertrieben - in England zur erfolgreichen Wissenschaftlerin gereift [The brain researcher Elisabeth Beck (1907-2002) - forced to flee from Germany - later successful scientific career in England].
Wunderlich, V.
In:
Schriftenreihe der DGGN 21 (2015).
Schriftenreihe der Deutschen Gesellschaft fuer Geschichte der Nervenheilkunde, 21
.
Koenigshausen & Neumann, Wuerzburg, Germany, 265-296.
ISBN 978-3-8260-5856-1
2015
Quantitative assessment of angiogenesis, perfused blood vessels and endothelial tip cells in the postnatal mouse brain.
Wälchli, T., Mateos, J.M., Weinman, O., Babic, D., Regli, L., Hoerstrup, S.P., Gerhardt, H., Schwab, M.E. and Vogel, J.
Nature Protocols 10
(1): 53-74.
January 2015
X
A systems view of epigenetic networks regulating pancreas development and β-cell function.
Xie, R., Carrano, A.C. and Sander, M.
Wiley Interdisciplinary Reviews Systems Biology and Medicine 7
(1): 1-11.
19 February 2015
Y
Selective probing of the penetration of dexamethasone into human skin by soft x-ray spectromicroscopy.
Yamamoto, K., Flesch, R., Ohigashi, T., Hedtrich, S., Klossek, A., Patoka, P., Ulrich, G., Ahlberg, S., Rancan, F., Vogt, A., Blume-Peytavi, U., Schrade, P., Bachmann, S., Schäfer-Korting, M., Kosugi, N. and Rühl, E.
Analytical Chemistry 87
(12): 6173–6179.
16 June 2015
Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.
You, X., Vlatkovic, I., Babic, A., Will, T., Epstein, I., Tushev, G., Akbalik, G., Wang, M., Glock, C., Quedenau, C., Wang, X., Hou, J., Liu, H., Sun, W., Sambandan, S., Chen, T., Schuman, E.M. and Chen, W.
Nature Neuroscience 18
(4): 603-610.
April 2015
Z
ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration.
Zandi, S., Nakao, S., Chun, K.H., Fiorina, P., Sun, D., Arita, R., Zhao, M., Kim, E., Schueller, O., Campbell, S., Taher, M., Melhorn, M.I., Schering, A., Gatti, F., Tezza, S., Xie, F., Vergani, A., Yoshida, S., Ishikawa, K., Yamaguchi, M., Sasaki, F., Schmidt-Ullrich, R., Hata, Y., Enaida, H., Yuzawa, M., Yokomizo, T., Kim, Y.B., Sweetnam, P., Ishibashi, T. and Hafezi-Moghadam, A.
Cell Reports 10
(7): 1173-1186.
24 February 2015
Discovering the mechanisms underlying serotonin (5-HT)2A and 5-HT2C receptor regulation following nicotine withdrawal in rats.
Zaniewska, M., Alenina, N., Wydra, K., Fröhler, S., Kuśmider, M., McCreary, A.C., Chen, W., Bader, M. and Filip, M.
Journal of Neurochemistry 134
(4): 704-716.
August 2015
Automated quantification of hematopoietic cell - stromal cell interactions in histological images of undecalcified bone.
Zehentmeier, S., Cseresnyes, Z., Escribano Navarro, J., Niesner, R.A. and Hauser, A.E.
Journal of Visualized Experiments
(98)
8 April 2015
Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multi-center survey.
Zeiser, R., Burchert, A., Lengerke, C., Verbeek, M., Maas-Bauer, K., Metzelder, S.K., Spoerl, S., Ditschkowski, M., Ecsedi, M., Sockel, K., Ayuk, F., Ajib, S., de Fontbrune, F.S., Na, I.K., Penter, L., Holtick, U., Wolf, D., Schuler, E., Meyer, E., Apostolova, P., Bertz, H., Marks, R., Lübbert, M., Wäsch, R., Scheid, C., Stölzel, F., Ordemann, R., Bug, G., Kobbe, G., Negrin, R., Brune, M., Spyridonidis, A., Schmitt-Gräff, A., van der Velden, W., Huls, G., Mielke, S., Grigoleit, G.U., Kuball, J., Flynn, R., Ihorst, G., Du, J., Blazar, B.R., Arnold, R., Kröger, N., Passweg, J., Halter, J., Socie, G., Beelen, D., Peschel, C., Neubauer, A., Finke, J., Duyster, J. and von Bubnoff, N.
Leukemia 29
(10): 2062-2068.
October 2015
An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression.
Zhang, B., Calado, D.P., Wang, Z., Froehler, S., Koechert, K., Qian, Y., Koralov, S.B., Schmidt-Supprian, M., Sasaki, Y., Unitt, C., Rodig, S., Chen, W., Dalla-Favera, R., Alt, F.W., Pasqualucci, L. and Rajewsky, K.
Cell Reports 11
(5): 715-726.
5 May 2015
Early life body fatness and risk of colorectal cancer in U.S. women and men: results from two large cohort studies.
Zhang, X., Wu, K., Giovannucci, E.L., Ma, J., Colditz, G.A., Fuchs, C.S., Willett, W.C., Stampfer, M.J., Nimptsch, K., Ogino, S. and Wei, E.K.
Cancer Epidemiology, Biomarkers & Prevention 24
(4): 690-697.
April 2015
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors.
Zhou, T., Lynch, R.M., Chen, L., Acharya, P., Wu, X., Doria-Rose, N.A., Joyce, M.G., Lingwood, D., Soto, C., Bailer, R.T., Ernandes, M.J., Kong, R., Longo, N.S., Louder, M.K., McKee, K., O'Dell, S., Schmidt, S.D., Tran, L., Yang, Z., Druz, A., Luongo, T.S., Moquin, S., Srivatsan, S., Yang, Y., Zhang, B., Zheng, A., Pancera, M., Kirys, T., Georgiev, I.S., Gindin, T., Peng, H.P., Yang, A.S., Mullikin, J.C., Gray, M.D., Stamatatos, L., Burton, D.R., Koff, W.C., Cohen, M.S., Haynes, B.F., Casazza, J.P., Connors, M., Corti, D., Lanzavecchia, A., Sattentau, Q.J., Weiss, R.A., West, A.P., Bjorkman, P.J., Scheid, J.F., Nussenzweig, M.C., Shapiro, L., Mascola, J.R. and Kwong, P.D.
Cell 161
(6): 1280-92.
4 June 2015
Role of CYP eicosanoids in the regulation of pharyngeal pumping and food uptake in Caenorhabditis elegans.
Zhou, Y., Falck, J.R., Rothe, M., Schunck, W.H. and Menzel, R.
Journal of Lipid Research 56
(11): 2110-2123.
November 2015
Four RNA families with functional transient structures.
Zhu, J.Y. and Meyer, I.M.
RNA Biology 12
(1): 5-20.
2015
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Zidek, L.M., Ackermann, T., Hartleben, G., Eichwald, S., Kortman, G., Kiehntopf, M., Leutz, A., Sonenberg, N., Wang, Z.Q., von Maltzahn, J., Müller, C. and Calkhoven, C.F.
EMBO Reports 16
(08): 1022-1036.
August 2015
A novel regulatory macrophage induced by a helminth molecule instructs IL-10 in CD4(+) T cells and protects against mucosal inflammation.
Ziegler, T., Rausch, S., Steinfelder, S., Klotz, C., Hepworth, M.R., Kühl, A.A., Burda, P.C., Lucius, R. and Hartmann, S.
Journal of Immunology 194
(4): 1555-1564.
15 February 2015
Pocket depth and bleeding on probing and their associations with dental, lifestyle, socioeconomic and blood variables: a cross-sectional, multicenter feasibility study of the German National Cohort.
Zimmermann, H., Hagenfeld, D., Diercke, K., El-Sayed, N., Fricke, J., Greiser, K.H., Kühnisch, J., Linseisen, J., Meisinger, C., Pischon, N., Pischon, T., Samietz, S., Schmitter, M., Steinbrecher, A., Kim, T.S. and Becher, H.
BMC Oral Health 15
(1): 7.
21 January 2015
Á
Epigenetic control of myeloid cell differentiation, identity and function.
Álvarez-Errico, D., Vento-Tormo, R., Sieweke, M. and Ballestar, E.
Nature Reviews Immunology 15
(1): 7-17.
January 2015
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