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  • Research Areas (15910)
    • Topic 2: Molecular Processes and Therapies (544)
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2024

Genetic determinants of micronucleus formation in vivo.
Adams, D.J. and Barlas, B. and McIntyre, R.E. and Salguero, I. and van der Weyden, L. and Barros, A. and Vicente, J.R. and Karimpour, N. and Haider, A. and Ranzani, M. and Turner, G. and Thompson, N.A. and Harle, V. and Olvera-León, R. and Robles-Espinoza, C.D. and Speak, A.O. and Geisler, N. and Weninger, W.J. and Geyer, S.H. and Hewinson, J. and Karp, N.A. and Fu, B. and Yang, F. and Kozik, Z. and Choudhary, J. and Yu, L. and van Ruiten, M.S. and Rowland, B.D. and Lelliott, C.J. and Del Castillo Velasco-Herrera, M. and Verstraten, R. and Bruckner, L. and Henssen, A.G. and Rooimans, M.A. and de Lange, J. and Mohun, T.J. and Arends, M.J. and Kentistou, K.A. and Coelho, P.A. and Zhao, Y. and Zecchini, H. and Perry, J.R.B. and Jackson, S.P. and Balmus, G.
Nature 627 (8002): 130–136. 7 March 2024

ADAM19 cleaves the PTH receptor and associates with brachydactyly type E.
Aydin, A. and Klenk, C. and Nemec, K. and Işbilir, Ali and Martin, L.M. and Zauber, H. and Rrustemi, T. and Toka, H.R. and Schuster, H. and Gong, M. and Stricker, S. and Bock, A. and Bähring, S. and Selbach, M. and Lohse, M.J. and Luft, F.C.
Life Science Alliance 7 (4): e202302400. April 2024

Activation of gp130 signaling in T cells drives T(H)17-mediated multi-organ autoimmunity.
Baumgartner, F. and Bamopoulos, S.A. and Faletti, L. and Hsiao, H.J. and Holz, M. and Gonzalez-Menendez, I. and Solé-Boldo, L. and Horne, A. and Gosavi, S. and Özerdem, C. and Singh, N. and Liebig, S. and Ramamoorthy, S. and Lehmann, M. and Demel, U. and Kühl, A.A. and Wartewig, T. and Ruland, J. and Wunderlich, F.T. and Schick, M. and Walther, W. and Rose-John, S. and Haas, S. and Quintanilla-Martinez, L. and Feske, S. and Ehl, S. and Glauben, R. and Keller, U.
Science Signaling 17 (824): eadc9662. 20 February 2024

Ion mobility-tandem mass spectrometry of mucin-type O-glycans.
Bechtella, L. and Chunsheng, J. and Fentker, K. and Ertürk, G.R. and Safferthal, M. and Polewski, Ł. and Götze, M. and Graeber, S.Y. and Vos, G.M. and Struwe, W.B. and Mall, M.A. and Mertins, P. and Karlsson, N.G. and Pagel, K.
Nature Communications 15 (1): 2611. 23 March 2024

Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer.
Bei, Y. and Brame, Luca and Kirchner, M. and Fritsche-Guenther, R. and Kunz, S. and Bhattacharya, A. and Rusu, M.C. and Gürgen, D. and Dubois, F.P.B. and Köppke, J.K.C. and Proba, J. and Wittstruck, N. and Sidorova, O.A. and Chamorro González, R. and Dorado Garcia, H. and Brückner, L. and Xu, R. and Giurgiu, M. and Rodriguez-Fos, E. and Yu, Q. and Spanjaard, B. and Koche, R.P, and Schmitt, C.A. and Schulte, J.H. and Eggert, A. and Haase, K. and Kirwan, J. and Hagemann, A.I. and Mertins, P. and Dörr, J.R. and Henssen, A.G.
Cancer Discovery 14 (3): 492-507. 1 March 2024

Polyglutamine disease proteins: Commonalities and differences in interaction profiles and pathological effects.
Bonsor, M. and Ammar, O. and Schnoegl, S. and Wanker, E.E. and Silva Ramos, E.
Proteomics : e2300114. 14 April 2024 (In Press)

Autophagy preserves hematopoietic stem cells by restraining MTORC1-mediated cellular anabolism.
Borsa, M. and Obba, S. and Richter, F.C. and Zhang, H. and Riffelmacher, T. and Carrelha, J. and Alsaleh, G. and Jacobsen, S.E.W. and Simon, A.K.
Autophagy 20 (1): 45-57. January 2024

A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
Brenner, D. and Sieverding, K. and Srinidhi, J. and Zellner, S. and Secker, C. and Yilmaz, R. and Dyckow, J. and Amr, S. and Ponomarenko, A. and Tunaboylu, E. and Douahem, Y. and Schlag, J.S. and Rodríguez Martínez, L. and Kislinger, G. and Niemann, C. and Nalbach, K. and Ruf, W.P. and Uhl, J. and Hollenbeck, J. and Schirmer, L. and Catanese, A. and Lobsiger, C.S. and Danzer, K.M. and Yilmazer-Hanke, D. and Münch, C. and Koch, P. and Freischmidt, A. and Fetting, M. and Behrends, C. and Parlato, R. and Weishaupt, J.H.
Journal of Experimental Medicine 221 (5): e20221190. 22 March 2024

Touch sensation requires the mechanically gated ion channel ELKIN1.
Chakrabarti, S. and Klich, J.D. and Khallaf, M.A. and Hulme, A.J. and Sánchez-Carranza, O. and Baran, Z.M. and Rossi, A. and Huang, A.T.L. and Pohl, T. and Fleischer, R. and Fürst, C. and Hammes, A. and Bégay, V. and Hörnberg, H. and Finol-Urdaneta, R.K. and Poole, K. and Dottori, M. and Lewin, G.
Science 383 (6686): 992-998. 1 March 2024

Reevaluating the relevance of F-FDG PET findings for diagnosis of neurosarcoidosis: a case series.
Chen, J. and Metzger, G. and Furth, C. and Bohner, G. and Siffrin, V.
Neurological Research and Practice 6 (1): 12. 25 January 2024

Efficient recovery of complete gut viral genomes by combined short- and long-read sequencing.
Chen, J. and Sun, C. and Dong, Y. and Jin, M. and Lai, S. and Jia, L. and Zhao, X. and Wang, H. and Gao, N.L. and Bork, P. and Liu, Z. and Chen, W.H. and Zhao, X.M.
Advanced Science 11 (13): 2305818. 3 April 2024

LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression.
Chen, W. and Wang, F. and Yu, X. and Qi, J. and Dong, H. and Cui, B. and Zhang, Q. and Wu, Y. and An, J. and Ni, N. and Liu, C. and Han, Y. and Zhang, S. and Schmitt, C.A. and Deng, J. and Yu, Y. and Du, J.
Oncogene 43 (18): 1328-1340. 2 May 2024

Next questions in autophagy.
Cuervo, A.M. and Elazar, Z. and Evans, C. and Ge, L. and Hansen, M. and Jäättelä, M. and Liang, J.R.A. and Loos, B. and Mizushima, N. and Simon, A.K. and Tooze, S. and Yoshimori, T. and Nakamura, S.
Nature Cell Biology 26 (5): 661-666. May 2024

Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2.
Desiderio, S. and Schwaller, F. and Tartour, K. and Padmanabhan, K. and Lewin, G.R. and Carroll, P. and Marmigere, F.
eLife 12 : RP89287. 22 February 2024

Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly.
Dick, A. and Mikirtumov, V. and Fuchs, J. and Krupp, F. and Olal, D. and Bendl, E. and Sprink, T. and Diebolder, C. and Kudryashev, M. and Kochs, G. and Roske, Y. and Daumke, O.
Structure 32 : 1–11.e1–e5. 8 August 2024 (In Press)

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.
Drexhage, L.Z. and Zhang, S. and Dupont, M. and Ragaller, F. and Sjule, E. and Cabezas-Caballero, J. and Deimel, L.P. and Robertson, H. and Russell, R.A. and Dushek, O. and Sezgin, E. and Karaji, N. and Sattentau, Q.J.
Nature Communications 15 (1): 541. 15 January 2024

Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice.
Dörmann, N. and Hammer, E. and Struckmann, K. and Rüdebusch, J. and Bartels, K. and Wenzel, K. and Schulz, J. and Gross, S. and Schwanz, S. and Martin, E. and Fielitz, B. and Pablo Tortola, C. and Hahn, A. and Benkner, A. and Völker, U. and Felix, S.B and Fielitz, J.
Frontiers in Cardiovascular Medicine 10 : 1323760. 8 January 2024

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer.
Erdem, M. and Lee, K.H. and Hardt, M. and Regan, J.L. and Kobelt, D. and Walther, W. and Mokrizkij, M. and Regenbrecht, C. and Stein, U.
Cancers 16 (3): 604. 31 January 2024

The diversity of the microbiome impacts chronic lymphocytic leukemia development in mice and humans.
Faitova, T. and Coelho, M. and Da Cunha-Bang, C. and Ozturk, S. and Kartal, E. and Bork, P. and Seiffert, M. and Niemann, C.U.
Haematologica 9 May 2024 (In Press)

The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
Fasciani, I. and Petragnano, F. and Wang, Z. and Edwards, R. and Telugu, N. and Pietrantoni, I. and Zabel, U. and Zauber, H. and Grieben, M. and Terzenidou, M.E. and Di Gregorio, J. and Pellegrini, C. and Santini, S. and Taddei, A.R. and Pohl, B. and Aringhieri, S. and Carli, M. and Aloisi, G. and Marampon, F. and Charlesworth, E. and Roman, A. and Diecke, S. and Flati, V. and Giorgi, F. and Amicarelli, F. and Tobin, A.B. and Scarselli, M. and Tokatlidis, K. and Rossi, M. and Lohse, M.J. and Annibale, P. and Maggio, R.
PLoS Biology 22 (4): e3002582. 29 April 2024

Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Flügel, T. and Schacherl, M. and Unbehaun, A. and Schroeer, B. and Dabrowski, M. and Bürger, J. and Mielke, T. and Sprink, T. and Diebolder, C.A. and Guillén Schlippe, Y.V. and Spahn, C.M.T.
Nature Communications 15 (1): 1756. 26 February 2024

BTK inhibition limits microglia‑perpetuated CNS inflammation and promotes myelin repair.
Geladaris, A. and Torke, S. and Saberi, D. and Alankus, Y.B. and Streit, F. and Zechel, S. and Stadelmann-Nessler, C. and Fischer, A. and Boschert, U. and Häusler, D. and Weber, M.S.
Acta Neuropathologica 147 (1): 75. 24 April 2024

Mesenchymal cell migration on one-dimensional micropatterns.
Heyn, J.C.J. and Rädler, J.O. and Falcke, M.
Frontiers in Cell and Developmental Biology 12 : 1352279. 16 April 2024

Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment.
Kaiser, R. and Gold, C. and Joppich, M. and Loew, Q. and Akhalkatsi, A. and Mueller, T.T. and Offensperger, F. and Droste Zu Senden, A. and Popp, O. and di Fina, L. and Knottenberg, V. and Martinez-Navarro, A. and Eivers, L. and Anjum, A. and Escaig, R. and Bruns, N. and Briem, E. and Dewender, R. and Muraly, A. and Akgöl, S. and Ferraro, B. and Hoeflinger, J.K.L. and Polewka, V. and Khaled, N.B. and Allgeier, J. and Tiedt, S. and Dichgans, M. and Engelmann, B. and Enard, W. and Mertins, P. and Hubner, N. and Weckbach, L. and Zimmer, R. and Massberg, S. and Stark, K. and Nicolai, L. and Pekayvaz, K.
Science Advances 10 (12): eadl1710. 22 March 2024

SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells.
Kalnytska, O. and Qvist, P. and Kunz, S. and Conrad, T. and Willnow, T.E. and Schmidt, V.
iScience 27 (1): 108725. 19 January 2024

CD19-targeting CAR T cells protect from ANCA-induced acute kidney injury.
Lodka, D. and Zschummel, M. and Bunse, M. and Rousselle, A. and Sonnemann, J. and Kettritz, R. and Höpken, U.E. and Schreiber, A.
Annals of the Rheumatic Diseases 83 (4): 499-507. 12 March 2024

Taste mapping: navigating the spatiotemporal link between diet and colorectal cancer.
Luo, Q. and Liu, Y. and Bi, M. and Kuai, X. and Tian, Q. and Sun, Y. and Zhuang, S.
IEEE Access 12 : 17735 - 17747. 30 January 2024

Canonical and non-canonical localization of tight junction proteins during early murine cranial development.
Mak, S. and Hammes, A.
International Journal of Molecular Sciences 25 (3): 1426. 24 January 2024

An automated and fast sample preparation workflow for laser microdissection guided ultrasensitive proteomics.
Makhmut, A. and Qin, D. and Hartlmayr, D. and Seth, A. and Coscia, F.
Molecular & Cellular Proteomics : 100750. 20 March 2024 (In Press)

Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model.
Mohan, A.M. and Prasad, S. and Schmitz-Peiffer, F. and Lange, C. and Lukas, M. and Koziolek, E.J. and Albrecht, J. and Messroghli, D. and Stein, U. and Ilmer, M. and Wang, K. and Schober, L. and Reul, A. and Maurer, J. and Friemel, J. and Weber, A. and Zuellig, R.A. and Hantel, C. and Fritsch, R. and Reincke, M. and Pacak, K. and Grossman, A.B. and Auernhammer, C.J. and Beuschlein, F. and Brenner, W. and Beindorff, N. and Nölting, S.
Endocrine-Related Cancer 31 (1): e230041. January 2024

AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication.
Monjé, N. and Dragomir, M.P. and Sinn, B.V. and Hoffmann, I. and Makhmut, A. and Simon, T. and Kunze, C.A. and Ihlow, J. and Schmitt, W.D. and Pohl, J. and Piwonski, I. and Marchenko, S. and Keunecke, C. and Calina, T.G. and Tiso, F. and Kulbe, H. and Kreuzinger, C. and Cacsire Castillo-Tong, D. and Sehouli, J. and Braicu, E.I. and Denkert, C. and Darb-Esfahani, S. and Kübler, K. and Capper, D. and Coscia, F. and Morkel, M. and Horst, D. and Sers, C. and Taube, E.T.
British Journal of Cancer 13 (8): 1249-1260. 3 May 2024

The zebrafish heart harbors a thermogenic beige fat depot analog of human epicardial adipose tissue.
Morocho-Jaramillo, P.A. and Kotlar-Goldaper, I. and Zakarauskas-Seth, B.I. and Purfürst, B. and Filosa, A. and Sawamiphak, S.
Cell Reports 43 (3): 113955. 26 March 2024

Mice with renal-specific alterations 1 of stem cell-associated signaling develop symptoms of chronic kidney disease but surprisingly no tumors.
Myszczyszyn, A. and Popp, O. and Kunz, S. and Sporbert, A. and Jung, S. and Penning, L.C. and Fendler, A. and Mertins, P. and Birchmeier, W.
PLoS ONE 19 (3): e0282938. 21 March 2024

High-throughput anaerobic screening for identifying compounds acting against gut bacteria in monocultures or communities.
Müller, P. and de la Cuesta-Zuluaga, J. and Kuhn, M. and Baghai Arassi, M. and Treis, T. and Blasche, S. and Zimmermann, M. and Bork, P. and Patil, K.R. and Typas, A. and Garcia-Santamarina, S. and Maier, L.
Nature Protocols 19 (3): 668-699. March 2024

Fluorescent tools for the imaging of dopamine D2-like receptors.
Nagl, M. and Moennich, D. and Rosier, N. and Schihada, H. and Sirbu, A. and Konar, N. and Reyes-Resina, I. and Navarro, G. and Franco, R. and Kolb, P. and Annibale, P. and Pockes, S.
ChemBioChem 25 (2): e202300659. 15 January 2024

Topological reaction coordinate captures the folding transition state ensemble in a pierced lasso protein.
Noel, J.K. and Haglund, E.
Journal of Physical Chemistry B 128 (1): 117-124. 11 January 2024

Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception.
Ojeda-Alonso, J. and Calvo-Enrique, L. and Paricio-Montesinos, R. and Kumar, R. and Zhang, M.D. and Poulet, J.F.A. and Ernfors, P. and Lewin, G.R.
Nature Communications 15 (1): 898. 6 February 2024

GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway.
Park, A.Y. and Leney-Greene, M. and Lynberg, M. and Gabrielski, J.Q. and Xu, X. and Schwarz, B. and Zheng, L. and Balasubramaniyam, A. and Ham, H. and Chao, B. and Zhang, Y. and Matthews, H.F. and Cui, J. and Yao, Y. and Kubo, S. and Chanchu, J.M. and Morawski, A.R. and Cook, S.A. and Jiang, P. and Ravell, J.C. and Cheng, Y.H. and George, A. and Faruqi, A. and Pagalilauan, A.M. and Bergerson, J.R.E. and Ganesan, S. and Chauvin, S.D. and Aluri, J. and Edwards-Hicks, J. and Bohrnsen, E. and Tippett, C. and Omar, H. and Xu, L. and Butcher, G.W. and Pascall, J. and Karakoc-Aydiner, E. and Kiykim, A. and Maecker, H. and Tezcan, İ. and Esenboga, S. and Heredia, R.J. and Akata, D. and Tekin, S. and Kara, A. and Kuloglu, Z. and Unal, E. and Kendirli, T. and Dogu, F. and Karabiber, E. and Atkinson, T.P. and Cochet, C. and Filhol, O. and Bosio, C.M. and Davis, M.M. and Lifton, R.P. and Pearce, E.L. and Daumke, O. and Aytekin, C. and Şahin, G.E. and Aksu, A.Ü. and Uzel, G. and Koneti Rao, V. and Sari, S. and Boztug, K. and Cagdas, D. and Haskologlu, S. and Ikinciogullari, A. and Schwefel, D. and Vilarinho, S. and Baris, S. and Ozen, A. and Su, H.C. and Lenardo, M.J.
Nature Immunology 25 (2): 282-293. February 2024

The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte coupling in mice.
Pelz, L. and Dossou, L. and Kompier, N. and Jüttner, R. and Siemonsmeier, G. and Meyer, N. and Lowenstein, E.D. and Lahmann, I. and Kettenmann, H. and Birchmeier, C. and Rathjen, F.G.
eNeuro 22 February 2024 (In Press)

Elimusertib has antitumor activity in preclinical patient-derived pediatric solid tumor models.
Pusch, F.F. and Dorado Garcia, H. and Xu, R. and Gürgen, D. and Bei, Y. and Brückner, L. and Röefzaad, C. and von Stebut, J. and Bardinet, V. and Chamorro Gonzalez, R. and Eggert, A. and Schulte, J.H. and Hundsdörfer, P. and Seifert, G. and Haase, K. and Schäfer, B.W. and Wachtel, M. and Kühl, A.A. and Ortiz, M.V. and Wengner, A.M. and Scheer, M. and Henssen, A.G.
Molecular Cancer Therapeutics 23 (4): 507-519. 2 April 2024

Selection on synonymous sites: the unwanted transcript hypothesis.
Radrizzani, S. and Kudla, G. and Izsvák, Z. and Hurst, L.D.
Nature Reviews Genetics 25 (6): 431-448. June 2024

Cellular senescence: Neither irreversible nor reversible.
Reimann, M. and Lee, S. and Schmitt, C.A.
Journal of Experimental Medicine 221 (4): e20232136. 1 April 2024

Functional and evolutionary significance of unknown genes from uncultivated taxa.
Rodríguez Del Río, Á. and Giner-Lamia, J. and Cantalapiedra, C.P. and Botas, J. and Deng, Z. and Hernández-Plaza, A. and Munar-Palmer, M. and Santamaría-Hernando, S. and Rodríguez-Herva, J.J. and Ruscheweyh, H.J. and Paoli, L. and Schmidt, T.S.B. and Sunagawa, S. and Bork, P. and López-Solanilla, E. and Coelho, L.P. and Huerta-Cepas, J.
Nature 626 (7998): 377-384. 8 February 2024

Shedding light on the D1‐like receptors: a fluorescence‐based toolbox for visualization of the D1 and D5 receptors.
Rosier, N. and Moennich, D. and Nagl, M. and Schihada, H. and Sirbu, A. and Konar, N. and Reyes-Resina, I. and Navarro, G. and Franco, R. and Kolb, P. and Annibale, P. and Pockes, S.
ChemBioChem 25 (2): e202300658. 15 January 2024

Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Roske, Y. and Cappel, C. and Cremer, N. and Hoffmann, P. and Koudelka, T. and Tholey, A. and Heinemann, U. and Daumke, O. and Damme, M.
Nucleic Acids Research 52 (1): 370-384. 11 January 2024

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions.
Rrustemi, T. and Meyer, K. and Roske, Y. and Uyar, B. and Akalin, A. and Imami, K. and Ishihama, Y. and Daumke, O. and Selbach, M.
Nature Communications 15 (1): 3146. 11 April 2024

Targeted proteomics reveals quantitative differences in low-abundance glycosyltransferases of patients with congenital disorders of glycosylation.
Sakson, R. and Beedgen, L. and Bernhard, P. and Alp, K.M. and Lübbehusen, N. and Röth, R. and Niesler, B. and Luzarowski, M. and Shevchuk, O. and Mayer, M.P. and Thiel, C. and Ruppert, T.
International Journal of Molecular Sciences 25 (2): 1191. 18 January 2024

TTF-1 status in early-stage lung adenocarcinoma is an independent predictor of relapse and survival superior to tumor grading.
Schallenberg, S. and Dernbach, G. and Dragomir, M.P. and Schlachtenberger, G. and Boschung, K. and Friedrich, C. and Standvoss, K. and Ruff, L. and Anders, P. and Grohé, C. and Randerath, W. and Merkelbach-Bruse, S. and Quaas, A. and Heldwein, M. and Keilholz, U. and Hekmat, J.K. and Rückert, C. and Büttner, R. and Horst, D. and Klauschen, F. and Frost, N.
European Journal of Cancer 197 : 113474. January 2024

The proteomic composition and organization of constitutive heterochromatin in mouse tissues.
Schmidt, A. and Zhang, H. and Schmitt, S. and Rausch, C. and Popp, O. and Chen, J. and Cmarko, D. and Butter, F. and Dittmar, G. and Lermyte, F. and Cardoso, M.C.
Cells 13 (2): 139. 11 January 2024

SPIRE: a Searchable, Planetary-scale mIcrobiome REsource.
Schmidt, T.S.B. and Fullam, A. and Ferretti, P. and Orakov, A. and Maistrenko, O.M. and Ruscheweyh, H.J. and Letunic, I. and Duan, Y. and Van Rossum, T. and Sunagawa, S. and Mende, D.R. and Finn, R.D. and Kuhn, M. and Pedro Coelho, L. and Bork, P.
Nucleic Acids Research 52 (D1): D777-D783. 5 January 2024

Impairment of the adrenergic reserve associated with exercise intolerance in a murine model of heart failure with preserved ejection fraction.
Semmler, L. and Jeising, T. and Huettemeister, J. and Bathe-Peters, M. and Georgoula, K. and Roshanbin, R. and Sander, P. and Fu, S. and Bode, D. and Hohendanner, F. and Pieske, B. and Annibale, P. and Schiattarella, G.G. and Oeing, C.U. and Heinzel, F.R.
Acta Physiologica 240 (4): e14124. April 2024

Advancing research and treatment: an overview of clinical trials in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and future perspectives.
Seton, K.A. and Espejo-Oltra, J.A. and Giménez-Orenga, K. and Haagmans, R. and Ramadan, D.J. and Mehlsen, J.
Journal of Clinical Medicine 13 (2): 325. 6 January 2024

Huntingtin protein–protein interactions: From biology to therapeutic targets.
Silva Ramos, E. and Greco, T.M. and Cristea, I.M. and Wanker, E.E.
In: Huntington's Disease. Elsevier, New York, NY, USA, 159-186. ISBN pub.1168955041 16 February 2024

Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Sun, G. and Kropp, K.A. and Kirchner, M. and Plückebaum, N. and Selich, A. and Serrero, M. and Dhingra, A. and Cabrera, J.R. and Ritter, B. and Bauerfeind, R. and Wyler, E. and Landthaler, M. and Schambach, A. and Sodeik, B. and Mertins, P. and Viejo-Borbolla, A.
mBio 15 (2): e0330823. 14 February 2024

EU-LIFE charter of independent life science research institutes.
Superti-Furga, G. and Agostinho, M. and Bury, J. and Cook, S. and Durinx, C. and Ender, A. and van Luenen, H. and Lund, A.H. and Medema, R.H. and Miączyńska, M. and Nickel, D. and Pelicci, P.G. and Puisieux, A. and Ripatti, S. and Sander, M. and Schubeler, D. and Serrano, L. and Sommer, T. and Sonne-Hansen, K. and Tomančák, P. and Vives, J. and Vontas, J. and Bettencourt-Dias, M.
FEBS Letters 21 March 2024

Review: Opportunities and barriers for omics-based biomarker discovery in steatotic liver diseases.
Thiele, M. and Villesen, I.. and Niu, L. and Johansen, S. and Sulek, K. and Nishijima, S. and Van Espen, L. and Keller, M. and Israelsen, M. and Suvitaival, T. and de Zawadzki, A. and Juel, H.B. and Brol, M.J. and Stinson, S.E. and Huang, Y. and Alvarez Silva, M.C. and Kuhn, M. and Anastasiadou, E. and Leeming, D.J. and Karsdal, M. and Matthijnssens, J. and Arumugam, M. and Dalgaard, L.T. and Legido-Quigley, C. and Mann, M. and Trebicka, J. and Bork, P. and Jensen, L.J. and Hansen, T. and Krag, A.
Journal of Hepatology 28 March 2024 (In Press)

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies.
Torke, S. and Walther, W. and Stein, U.
Cancers 16 (7): 1330. 28 March 2024

AI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor.
Trepte, P. and Secker, C. and Olivet, J. and Blavier, J. and Kostova, S. and Maseko, S.B. and Minia, I. and Silva Ramos, E. and Cassonnet, P. and Golusik, S. and Zenkner, M. and Beetz, S. and Liebich, M.J. and Scharek, N. and Schutz, A. and Sperling, M. and Lisurek, M. and Wang, Y. and Spirohn, K. and Hao, T. and Calderwood, M.A. and Hill, D.E. and Landthaler, M. and Choi, S.G. and Twizere, J.C. and Vidal, M. and Wanker, E.E.
Molecular Systems Biology 20 (4): 428-457. 2 April 2024

KCNQ5 controls perivascular adipose tissue–mediated vasodilation.
Tsvetkov, D. and Schleifenbaum, J. and Wang, Y. and Kassmann, M. and Polovitskaya, M.M. and Ali, M. and Schütze, S. and Rothe, M. and Luft, F.C. and Jentsch, T.J. and Gollasch, M.
Hypertension 81 (3): 561-571. March 2024

Microglial sex differences in innate high anxiety and modulatory effects of minocycline.
Ugursu, B. and Sah, A. and Sartori, S. and Popp, O. and Mertins, P. and Dunay, I.R. and Kettenmann, H. and Singewald, N. and Wolf, S.A.
Brain, Behavior and Immunity 27 March 2024 (In Press)

Structural insights into the activation mechanism of antimicrobial GBP1.
Weismehl, M. and Chu, X. and Kutsch, M. and Lauterjung, P. and Herrmann, C. and Kudryashev, M. and Daumke, O.
EMBO Journal 43 (4): 615-636. 15 February 2024

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma.
Yalcin, F. and Haneke, H. and Efe, I.E. and Kuhrt, L.D. and Motta, E. and Nickl, B. and Flüh, C. and Synowitz, M. and Dzaye, O. and Bader, M. and Kettenmann, H.
Acta Neuropathologica Communications 12 (1): 50. 2 April 2024

2023

MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous, E.T. and Stolzenberg, S. and Sticht, J. and Wieczorek, M. and Roske, Y. and Günther, M. and Dähn, S. and Boesen, B.B. and Calvo, M.M. and Biese, C. and Kuppler, F. and Medina-García, Á. and Álvaro-Benito, M. and Höfer, T. and Noé, F. and Freund, C.
Nature Chemical Biology 19 (10): 1196-1204. October 2023

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor.
Aguirre, T. and Hostachy, S. and Dornan, G.L. and Neuenschwander, M. and Seyffarth, C. and Haucke, V. and Schütz, A. and von Kries, J.P. and Fiedler, D.
eLife 21 : RP88982. 16 October 2023

The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions.
Ahmed, S.M. and Ragunathan, P. and Shin, J. and Peter, S. and Kleissle, S. and Neuenschwander, M. and Schäfer, R. and von Kries, J.P. and Grüber, G. and Dröge, P.
FEBS Letters 597 (15): 1977-1988. August 2023

Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Alcaniz, J. and Winkler, L. and Dahlmann, M. and Becker, M. and Orthmann, A. and Haybaeck, J. and Krassnig, S. and Skofler, C. and Kratzsch, T. and Kuhn, S.A. and Jödicke, A. and Linnebacher, M. and Fichtner, I. and Walther, W. and Hoffmann, J.
Frontiers in Oncology 13 : 1129627. 11 April 2023

Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Alteen, M.G. and Deme, J.C. and Alvarez, C.P. and Loppnau, P. and Hutchinson, A. and Seitova, A. and Chandrasekaran, R. and Silva Ramos, E. and Secker, C. and Alqazzaz, M. and Wanker, E.E. and Lea, S.M. and Arrowsmith, C.H. and Harding, R.J.
Structure 31 (9): 1121-1131.e6. 7 September 2023

On multistability and constitutive relations of cell motion on Fibronectin lanes.
Amiri, B. and Heyn, J.C.J. and Schreiber, C. and Rädler, J.O. and Falcke, M.
Biophysical Journal 122 (5): 753-766. 7 March 2023

Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR.
Balyschew, N. and Yushkevich, A. and Mikirtumov, V. and Sanchez, R.M. and Sprink, T. and Kudryashev, M.
Nature Communications 14 (1): 6543. 17 October 2023

Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M. and Terkelsen, T. and Bartels, A.S. and Coscia, F. and Doll, S. and Zhao, S. and Zhang, Z. and Brünner, N. and Lindebjerg, J. and Madsen, G.I. and Fang, X. and Mann, M. and Moreira, J.M.A.
Gastroenterology 165 (1): 121-132.e5. July 2023

Establishment and thorough characterization of xenograft (PDX) models derived from patients with pancreatic cancer for molecular analyses and chemosensitivity testing.
Behrens, D. and Pfohl, U. and Conrad, T. and Becker, M. and Brzezicha, B. and Büttner, B. and Wagner, S. and Hallas, C. and Lawlor, R. and Khazak, V. and Linnebacher, M. and Wartmann, T. and Fichtner, I. and Hoffmann, J. and Dahlmann, M. and Walther, W.
Cancers 15 (24): 5753. 8 December 2023

A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A. and Haenig, C. and Neuendorf, N. and Blanc, E. and Ivanov, A. and Kirchner, M. and Schleumann, P. and Bayraktaroğlu, I. and Richter, M. and Molenda, C.M. and Sporbert, A. and Zenkner, M. and Schnoegl, S. and Suenkel, C. and Schneider, L.S. and Rybak-Wolf, A. and Kochnowsky, B. and Byrne, L.M. and Wild, E.J. and Nielsen, J.E. and Dittmar, G. and Peters, O. and Beule, D. and Wanker, E.E.
Genome Medicine 15 (1): 50. 20 July 2023

Combining metabolic pulse labeling and quantitative proteomics to monitor protein synthesis upon viral infection.
Bogdanow, B. and Katsimani, N. and Liu, F. and Selbach, M.
Methods in Molecular Biology 2610 : 149-165. 2023

Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness.
Breun, M. and Flock, K. and Feldheim, J. and Nattmann, A. and Monoranu, C.M. and Herrmann, P. and Ernestus, R.I. and Löhr, M. and Hagemann, C. and Stein, U.
Cancers 15 (16): 4089. 14 August 2023

Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F. and Noerenberg, D. and Hennch, C. and Yoshida, K. and Hablesreiter, R. and Nimo, J. and Sasca, D. and Kirchner, M. and Mansouri, L. and Inoue, Y. and Wiegand, L. and Staiger, A.M. and Casadei, B. and Korkolopoulou, P. and Weiner, J. and Lopez-Guillermo, A. and Warth, A. and Schneider, T. and Nagy, Á. and Klapper, W. and Hummel, M. and Kanellis, G. and Anagnostopoulos, I. and Mertins, P. and Bullinger, L. and Rosenquist, R. and Vassilakopoulos, T.P. and Ott, G. and Ogawa, S. and Damm, F.
Leukemia 37 (11): 2237-2249. November 2023

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R. and Conrad, T. and Stöber, M.C. and Xu, R. and Giurgiu, M. and Rodriguez-Fos, E. and Kasack, K. and Brückner, L. and van Leen, E. and Helmsauer, K. and Dorado Garcia, H. and Stefanova, M.E. and Hung, K.L. and Bei, Y. and Schmelz, K. and Lodrini, M. and Mundlos, S. and Chang, H.Y. and Deubzer, H.E. and Sauer, S. and Eggert, A. and Schulte, J.H. and Schwarz, R.F. and Haase, K. and Koche, R.P. and Henssen, A.G.
Nature Genetics 55 (5): 880-890. May 2023

Determining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging.
Chang, S.Y.S. and Dijkman, P.M. and Wiessing, S.A. and Kudryashev, M.
Scientific Reports 13 : 11523. 17 July 2023

Mepolizumab as an effective treatment in a case of hypophysitis in eosinophilic granulomatosis with polyangiitis.
Chen, J. and Alexander, T. and Walter-Rittel, T. and Ziagaki, A. and Siffrin, V.
Therapeutic Advances in Neurological Disorders 16 : 17562864231182519. 2023

TREM2 promotes glioma progression and angiogenesis mediated by microglia/brain macrophages.
Chen, X. and Zhao, Y. and Huang, Y. and Zhu, K. and Zeng, F. and Zhao, J. and Zhang, H. and Zhu, X. and Kettenmann, H. and Xiang, X.
Glia 71 (11): 2679-2695. November 2023

Mechanisms of substrate processing during ER-associated protein degradation.
Christianson, J.C. and Jarosch, E. and Sommer, T.
Nature Reviews Molecular Cell Biology 24 (11): 777-796. November 2023

Gentle ions for cryo-FIB milling.
Chu, X. and Kudryashev, M.
Structure 31 (10): 1147-1148. 5 October 2023

Touch receptor end-organ innervation and function requires sensory expression of the transcription factor Meis2.
Desiderio, S. and Schwaller, F. and Tartour, K. and Padmanabhan, K. and Lewin, G.R. and Carroll, P. and Marmigère, F.
bioRxiv : 2022.04.28.489889. 6 November 2023

HMGXB4 targets Sleeping Beauty transposition to germinal stem cells.
Devaraj, A. and Singh, M. and Narayanavari, S.A. and Yong, G. and Chen, J. and Wang, J. and Becker, M. and Walisko, O. and Schorn, A. and Cseresznyés, Z. and Raskó, T. and Radscheit, K. and Selbach, M. and Ivics, Z. and Izsvak, Z.
International Journal of Molecular Sciences 24 (8): 7283. 14 April 2023

N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness.
Dong, Hongliang and Zeng, Lili and Chen, Weiwei and Zhang, Qian and Wang, Fei and Wu, Yan and Cui, Bingjie and Qi, Jingjing and Zhang, Xin and Liu, Cuilan and Deng, Jiong and Yu, Y. and Schmitt, C.A. and Du, Jing
Cell Death Discovery 9 (1): 149. 6 May 2023

Targeting B cells and microglia in multiple sclerosis with Bruton tyrosine kinase inhibitors: a review.
Dybowski, S. and Torke, S. and Weber, M.S.
JAMA Neurology 80 (4): 404-414. 1 April 2023

Mutations in phosphodiesterase 3A (PDE3A) cause hypertension without cardiac damage.
Ercu, M. and Walter, S. and Klussmann, E.
Hypertension 80 (6): 1171-1179. June 2023

Parallel in-depth analysis of repeat expansions in ataxia patients by long-read sequencing.
Erdmann, H. and Schöberl, F. and Giurgiu, M. and Leal Silva, R.M. and Scholz, V. and Scharf, F. and Wendlandt, M. and Kleinle, S. and Deschauer, M. and Nübling, G. and Heide, W. and Babacan, S.S. and Schneider, C. and Neuhann, T. and Hahn, K. and Schoser, B. and Holinski-Feder, E. and Wolf, D.A. and Abicht, A.
Brain 146 (5): 1831-1843. May 2023

Thioester and oxyester linkages in the ubiquitin system.
Ferri-Blazquez, A. and Jarosch, E. and Sommer, T.
Methods in Molecular Biology 2602 : 3-18. 2023

A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O. and Jia, A. and Kuehn, H.S. and Min, Q. and Pannicke, U. and Schleussner, N. and Thouenon, R. and Yu, Z. and de Los Angeles Astbury, M. and Biggs, C.M. and Galicchio, M. and Garcia-Campos, J.A. and Gismondi, S. and Gonzalez Villarreal, G. and Hildebrand, K.J. and Hönig, M. and Hou, J. and Moshous, D. and Pittaluga, S. and Qian, X. and Rozmus, J. and Schulz, A.S. and Staines-Boone, A.T. and Sun, B. and Sun, J. and Uwe, S. and Venegas-Montoya, E. and Wang, W. and Wang, X. and Ying, W. and Zhai, X. and Zhou, Q. and Akalin, A. and André, I. and Barth, T.F.E. and Baumann, B. and Brüstle, A. and Burgio, G. and Bustamante, J.C. and Casanova, J.L. and Casarotto, M.G. and Cavazzana, M. and Chentout, L. and Cockburn, I.A. and Costanza, M. and Cui, C. and Daumke, O. and Del Bel, K.L. and Eibel, H. and Feng, X. and Franke, V. and Gebhardt, J.C.M. and Götz, A. and Grunwald, S. and Hoareau, B. and Hughes, T.R. and Jacobsen, E.M. and Janz, M. and Jolma, A. and Lagresle-Peyrou, C. and Lai, N. and Li, Y. and Lin, S. and Lu, H.Y. and Lugo-Reyes, S.O. and Meng, X. and Möller, P. and Moreno-Corona, N. and Niemela, J.E. and Novakovsky, G. and Perez-Caraballo, J.J. and Picard, C. and Poggi, L. and Puig-Lombardi, M.E. and Randall, K.L. and Reisser, A. and Schmitt, Y. and Seneviratne, S. and Sharma, M. and Stoddard, J. and Sundararaj, S. and Sutton, H. and Tran, L.Q. and Wang, Y. and Wasserman, W.W. and Wen, Z. and Winkler, W. and Xiong, E. and Yang, A.W.H. and Yu, M. and Zhang, L. and Zhang, H. and Zhao, Q. and Zhen, X. and Enders, A. and Kracker, S. and Martinez-Barricarte, R. and Mathas, S. and Rosenzweig, S.D. and Schwarz, K. and Turvey, S.E. and Wang, J.Y.
Science Immunology 8 (79): eade7953. January 2023

Cesium activates the neurotransmitter receptor for glycine.
Fricke, S. and Harnau, M. and Hetsch, F. and Liu, H. and Leonhard, J. and Eylmann, A. and Knauff, P. and Sun, H. and Semtner, M. and Meier, J.C.
Frontiers in Molecular Neuroscience 16 : 1018530. 22 May 2023

Modeling IP(3)-induced Ca(2+) signaling based on its interspike interval statistics.
Friedhoff, V.N. and Lindner, B. and Falcke, M.
Biophysical Journal 122 (13): 2818-2831. 11 July 2023

Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
Fuchs, S. and Danßmann, C. and Klironomos, F. and Winkler, A. and Fallmann, J. and Kruetzfeldt, L.M. and Szymansky, A. and Naderi, J. and Bernhart, S.H. and Grunewald, L. and Helmsauer, K. and Rodriguez-Fos, E. and Kirchner, M. and Mertins, P. and Astrahantseff, K. and Suenkel, C. and Toedling, J. and Meggetto, F. and Remke, M. and Stadler, P.F. and Hundsdoerfer, P. and Deubzer, H.E. and Künkele, A. and Lang, P. and Fuchs, J. and Henssen, A.G. and Eggert, A. and Rajewsky, N. and Hertwig, F. and Schulte, J.H.
Nature Communications 14 (1): 3936. 4 July 2023

Protein biomarkers in blood reflect the interrelationships between stroke outcome, inflammation, coagulation, adhesion, senescence and cancer.
Fuellen, G. and Walter, U. and Henze, L. and Böhmert, J. and Palmer, D. and Lee, S. and Schmitt, C.A. and Rudolf, H. and Kowald, A.
Cellular and Molecular Neurobiology 43 (4): 1413-1424. May 2023

proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes.
Fullam, A. and Letunic, I. and Schmidt, T.S.B. and Ducarmon, Q.R. and Karcher, N. and Khedkar, S. and Kuhn, M. and Larralde, M. and Maistrenko, O.M. and Malfertheiner, L. and Milanese, A. and Rodrigues, J.F.M. and Sanchis-López, C. and Schudoma, C. and Szklarczyk, D. and Sunagawa, S. and Zeller, G. and Huerta-Cepas, J. and von Mering, C. and Bork, P. and Mende, D.R.
Nucleic Acids Research 51 (D1): D760-D766. 6 January 2023

Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function.
Geng, S. and Paul, F. and Kowalczyk, I. and Raimundo, S. and Sporbert, A. and Mamo, T.M. and Hammes, A.
Frontiers in Cell and Developmental Biology 11 : 1173688. 7 April 2023

Quantitative morphological analysis of the T-tubular network of ventricular cardiomyocytes using novel image processing tools.
Georgoula, K. and Sage, D. and Annibale, P.
In: European Conferences on Biomedical Optics 2023, 25-29 June 2023, Munich, Germany. 11 August 2023

Proteostasis in T cell aging.
Gressler, A.E. and Leng, H. and Zinecker, H. and Simon, A.K.
Seminars in Immunology 70 : 101838. November 2023

Sex-specific microglia state in the neuroligin-4 knock-out mouse model of autism spectrum disorder.
Guneykaya, D. and Ugursu, B. and Logiacco, F. and Popp, O. and Feiks, M.A. and Meyer, N. and Wendt, S. and Semtner, M. and Cherif, F. and Gauthier, C. and Madore, C. and Yin, Z. and Çınar, Ö. and Arslan, T. and Gerevich, Z. and Mertins, P. and Butovsky, O. and Kettenmann, H. and Wolf, S.A.
Brain Behavior and Immunity 111 : 61-75. July 2023

Enhanced biosafety of the Sleeping Beauty transposon system by using mRNA as source of transposase to efficiently and stably transfect retinal pigment epithelial cells.
Harmening, N. and Johnen, S. and Izsvák, Z. and Ivics, Z. and Kropp, M. and Bascuas, T. and Walter, P. and Kreis, A. and Pajic, B. and Thumann, G.
Biomolecules 13 (4): 658. 7 April 2023

SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Heynen, G.J.J.E. and Baumgartner, F. and Heider, M. and Patra, U. and Holz, M. and Braune, J. and Kaiser, M. and Schäffer, I. and Bamopoulos, S.A. and Ramberger, E. and Murgai, A. and Ng, Y.L.D. and Demel, U.M. and Laue, D. and Liebig, S. and Krüger, J. and Janz, M. and Nogai, A. and Schick, M. and Mertins, P. and Müller, S. and Bassermann, F. and Krönke, J. and Keller, U. and Wirth, M.
Blood Advances 7 (4): 469-481. 28 February 2023

The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies.
Hoffmann, J. and Hanß, S. and Kraus, M. and Schaller, J. and Schäfer, C. and Stahl, D. and Anker, S.D. and Anton, G. and Bahls, T. and Blankenberg, S. and Blumentritt, A. and Boldt, L.H. and Cordes, S. and Desch, S. and Doehner, W. and Dörr, M. and Edelmann, F. and Eitel, I. and Endres, M. and Engelhardt, S. and Erdmann, J. and Eulenburg, K. and Falk, V. and Felix, S.B. and Frank, D. and Franke, T. and Frey, N. and Friede, T. and Geidel, L. and Germans, L. and Grabmaier, U. and Halle, M. and Hausleiter, J. and Jakobi, V. and Jebran, A.F. and Jobs, A. and Kääb, S. and Karakas, M. and Katus, H.A. and Klatt, A. and Knosalla, C. and Krebser, J. and Landmesser, U. and Lee, M. and Lehnert, K. and Lesser, S. and Leyh, K. and Lorbeer, R. and Mach-Kolb, S. and Meder, B. and Nagel, E. and Nolte, C.H. and Parwani, A.S. and Petersmann, A. and Puls, M. and Rau, H. and Reiser, M. and Rienhoff, O. and Scharfe, T. and Schattschneider, M. and Scheel, H. and Schnabel, R.B. and Schuster, A. and Schmitt, B. and Seidler, T. and Seiffert, M. and Stähli, B.E. and Stas, A. and Stocker, T.J. and von Stülpnagel, L. and Thiele, H. and Wachter, R. and Wakili, R. and Weis, T. and Weitmann, K. and Wichmann, H.E. and Wild, P. and Zeller, T. and Hoffmann, W. and Zeisberg, E.M. and Zimmermann, W.H. and Krefting, D. and Kühne, T. and Peters, A. and Hasenfuß, G. and Massberg, S. and Sommer, T. and Dimmeler, S. and Eschenhagen, T. and Nauck, M.
Clinical Research in Cardiology 112 (7): 923-941. July 2023

Monitoring mitochondrial translation by pulse SILAC.
Imami, K. and Selbach, M. and Ishihama, Y.
Journal of Biological Chemistry 299 (2): 102865. February 2023

Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda et al.
Immisch, L. and Papafotiou, G. and Popp, O. and Mertins, P. and Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 11 (3): e006784. 14 March 2023

Small molecule specifically inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation.
Jordan, P. and Costa, A. and Specker, E. and Popp, O. and Volkamer, A. and Piske, R. and Obrusnik, T. and Kleissle, S. and Stuke, K. and Rex, A. and Neuenschwander, M. and von Kries, J.P. and Nazare, M. and Mertins, P. and Kettenmann, H. and Wolf, S.A.
PLoS ONE 18 (2): e0278325. 6 February 2023

Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
Kapell, H. and Fazio, L. and Dyckow, J. and Schwarz, S. and Cruz-Herranz, A. and Campos, J. and Mayer, C. and D Este, E. and Möbius, W. and Cordano, C. and Pröbstel, A.K. and Gharagozloo, M. and Zulji, A. and Narayanan Naik, V. and Delank, A.K. and Cerina, M. and Müntefering, T. and Lerma-Martin, C. and Sonner, J.K. and Sin, J.H. and Disse, P. and Rychlik, N. and Sabeur, K. and Chavali, M. and Srivastava, R. and Heidenreich, M. and Fitzgerald, K.C. and Seebohm, G. and Stadelmann, C. and Hemmer, B. and Platten, M. and Jentsch, T.J. and Engelhardt, M. and Budde, T. and Nave, K.A. and Calabresi, P.A. and Friese, M.A. and Green, A.J. and Acuna, C. and Rowitch, D.H. and Meuth, S.G. and Schirmer, L.
Journal of Clinical Investigation 133 (7): e164223. 3 April 2023

Spatiotemporal GPCR signaling illuminated by genetically encoded fluorescent biosensors.
Kayser, C. and Melkes, B. and Derieux, C. and Bock, A.
Current Opinion in Pharmacology 71 : 102384. August 2023

Efficient determination of the accessible conformation space of multi-domain complexes based on EPR PELDOR data.
Kazemi, S. and Lopata, A. and Kniss, A. and Pluska, L. and Güntert, P. and Sommer, T. and Prisner, T.F. and Collauto, A. and Dötsch, V.
Journal of Biomolecular NMR 77 (5-6): 261-269. December 2023

The central role of DNA damage in immunosenescence.
Kell, L. and Simon, A.K. and Alsaleh, G. and Cox, L.S.
Frontiers in Aging 4 : 1202152. 3 July 2023

IFNγ binding to extracellular matrix prevents fatal systemic toxicity.
Kemna, J. and Gout, E. and Daniau, L. and Lao, J. and Weißert, K. and Ammann, S. and Kühn, R. and Richter, M. and Molenda, C. and Sporbert, A. and Zocholl, D. and Klopfleisch, R. and Schütz, A. and Lortat-Jacob, H. and Aichele, P. and Kammertoens, T. and Blankenstein, T.
Nature Immunology 24 (3): 414-422. March 2023

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies.
Kennedy, K.M. and de Goffau, M.C. and Perez-Muñoz, M.E. and Arrieta, M.C. and Bäckhed, F. and Bork, P. and Braun, T. and Bushman, F.D. and Dore, J. and de Vos, W.M. and Earl, A.M. and Eisen, J.A. and Elovitz, M.A. and Ganal-Vonarburg, S.C. and Gänzle, M.G. and Garrett, W.S. and Hall, L.J. and Hornef, M.W. and Huttenhower, C. and Konnikova, L. and Lebeer, S. and Macpherson, A.J. and Massey, R.C. and McHardy, A.C. and Koren, O. and Lawley, T.D. and Ley, R.E. and O'Mahony, L. and O'Toole, P.W. and Pamer, E.G. and Parkhill, J. and Raes, J. and Rattei, T. and Salonen, A. and Segal, E. and Segata, N. and Shanahan, F. and Sloboda, D.M. and Smith, G.C.S. and Sokol, H. and Spector, T.D. and Surette, M.G. and Tannock, G.W. and Walker, A.W. and Yassour, M. and Walter, J.
Nature 613 (7945): 639-649. 26 January 2023

iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J. and Muinjonov, B. and Rosiewicz, K.S. and Diecke, S. and Biese, C. and Schiweck, J. and Chien, C. and Zocholl, D. and Conrad, T. and Paul, F. and Alisch, M. and Siffrin, V.
Journal of Clinical Investigation 133 (13): e164637. 3 July 2023

Many kinases for controlling the water channel aquaporin‐2.
Kharin, A. and Klussmann, E.
Journal of Physiology 13 July 2023 (In Press)

Aquaporin-2 is not alone.
Klussmann, E.
Kidney International 103 (3): 458-460. March 2023

Resolving crosstalk between signaling pathways using mathematical modeling and time-resolved single cell data.
Konrath, F. and Loewer, A. and Wolf, J.
Methods in Molecular Biology 2634 : 267-284. 2023

A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1.
Konrath, F. and Willenbrock, M. and Busse, D. and Scheidereit, C. and Wolf, J.
iScience 26 (10): 107917. 20 October 2023

Studies in zebrafish and rat models support dual blockade of EP2 and EP4 (prostaglandin E(2) receptors type 2 and 4) for renoprotection in glomerular hyperfiltration and albuminuria.
Kourpa, A. and Schulz, A. and Mangelsen, E. and Kaiser-Graf, D. and Koppers, N. and Stoll, M. and Rothe, M. and Bader, M. and Purfürst, B. and Kunz, S. and Gladytz, T. and Niendorf, T. and Bachmann, S. and Mutig, K. and Bolbrinker, J. and Panakova, D. and Kreutz, R.
Hypertension 80 (4): 771-782. April 2023

Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia.
Kuhrt, L.D. and Motta, E. and Elmadany, N. and Weidling, H. and Fritsche-Guenther, R. and Efe, I.E. and Cobb, O. and Chatterjee, J. and Boggs, L.G. and Schnauß, M. and Diecke, S. and Semtner, M. and Anastasaki, C. and Gutmann, D.H. and Kettenmann, H.
Disease Models & Mechanisms 16 (12): dmm049861. December 2023

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch, J. and Theisen, S. and Dartsch, J. and Fritsche-Guenther, R. and Kirchner, M. and Obermayer, B. and Bauer, A. and Kahlert, A.K. and Rothe, M. and Beule, D. and Heuser, A. and Mertins, P. and Kirwan, J.A. and Berndt, N. and MacRae, C.A. and Hubner, N. and Klaassen, S.
Cardiovascular Research 119 (18): 2902-2916. December 2023

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch, J. and Theisen, S. and Dartsch, J. and Fritsche-Guenther, R. and Kirchner, M. and Obermayer, B. and Bauer, A. and Kahlert, A.K. and Rothe, M. and Beule, D. and Heuser, A. and Mertins, P. and Kirwan, J.A. and Berndt, N. and MacRae, C.A. and Hubner, N. and Klaassen, S.
bioRxiv : 2023.01.10.523243. 10 January 2023

Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B cell impairment and increases the risk for infections - a retrospective matched cohort study.
Launspach, M. and Temel, D. and Ohlendorf, E. and Zirngibl, F. and Materne, B. and Oevermann, L. and Deubzer, H.E. and Henssen, A.G. and Künkele, A. and Hundsdörfer, P. and von Bernuth, H. and Pruß, A. and Eggert, A. and von Stackelberg, A. and Lang, P. and Schulte, J.H.
Haematologica 108 (1): 267-272. January 2023

Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.
Li, B. and Zeis, P. and Zhang, Y. and Alekseenko, A. and Fürst, E. and Sanchez, Y.P. and Lin, G. and Tekkedil, M.M. and Piazza, I. and Steinmetz, L.M. and Pelechano, V.
Nature Communications 14 (1): 910. 17 February 2023

A weak-labelling and deep learning approach for in-focus object segmentation in 3D widefield microscopy.
Li, R. and Kudryashev, M. and Yakimovich, A.
Scientific Reports 13 (1): 12275. 28 July 2023

SPSB1-mediated inhibition of TGF-β receptor-II impairs myogenesis in inflammation.
Li, Y. and Dörmann, N. and Brinschwitz, B. and Kny, M. and Martin, E. and Bartels, K. and Li, N. and Giri, P.V. and Schwanz, S. and Boschmann, M. and Hille, S. and Fielitz, B. and Wollersheim, T. and Grunow, J. and Felix, S.B. and Weber-Carstens, S. and Luft, F.C. and Müller, O.J. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 14 (4): 1721-1736. August 2023

SLAM-Drop-seq reveals mRNA kinetic rates throughout the cell cycle.
Liu, H. and Arsiè, R. and Schwabe, D. and Schilling, M. and Minia, I. and Alles, J. and Boltengagen, A. and Kocks, C. and Falcke, M. and Friedman, N. and Landthaler, M. and Rajewsky, N.
Molecular Systems Biology 19 (10): e11427. 12 October 2023

Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels.
Liu, H. and Polovitskaya, M.M. and Yang, L. and Li, M. and Li, H. and Han, Z. and Wu, J. and Zhang, Q. and Jentsch, T.J. and Liao, J.
Cell Reports 42 (8): 112926. 29 August 2023

Targeting cAMP signaling compartments in iPSC-derived models of cardiovascular disease.
Liu, T. and Klussmann, E.
Current Opinion in Pharmacology 71 : 102392. August 2023

Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.
Lluch, A. and Latorre, J. and Serena-Maione, A. and Espadas, I. and Caballano-Infantes, E. and Moreno-Navarrete, J.M. and Oliveras-Cañellas, N. and Ricart, W. and Malagón, M.M. and Martin-Montalvo, A. and Birchmeier, W. and Szymanski, W. and Graumann, J. and Gómez-Serrano, M. and Sommariva, E. and Fernández-Real, J.M. and Ortega, F.J.
Nature Communications 14 (1): 5106. 22 August 2023

Development of selective inhibitors of phosphatidylinositol 3-kinase C2α.
Lo, W.T. and Belabed, H. and Kücükdisli, M. and Metag, J. and Roske, Y. and Prokofeva, P. and Ohashi, Y. and Horatscheck, A. and Cirillo, D. and Krauss, M. and Schmied, C. and Neuenschwander, M. and von Kries, J.P. and Médard, G. and Kuster, Be. and Perisic, O. and Williams, R.L. and Daumke, O. and Payrastre, B. and Severin, S. and Nazaré, M. and Haucke, V.
Nature Chemical Biology 19 (1): 18-27. January 2023

Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic.
Logiacco, F. and Grzegorzek, L.C. and Cordell, E.C. and Popp, O. and Mertins, P. and Gutmann, D.H. and Kettenmann, H. and Semtner, M.
Acta Neuropathologica Communications 11 (1): 36. 9 March 2023

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility.
Lowenstein, E.D. and Ruffault, P.L. and Misios, A. and Osman, K.L. and Li, H. and Greenberg, R.S. and Thompson, R. and Song, K. and Dietrich, S. and Li, X. and Vladimirov, N. and Woehler, A. and Brunet, J.F. and Zampieri, N. and Kühn, R. and Liberles, S.D. and Jia, S. and Lewin, G.R. and Rajewsky, N. and Lever, T.E. and Birchmeier, C.
Neuron 111 (14): 2184-2200.e7. 19 July 2023

A framework for ultra-low-input spatial tissue proteomics.
Makhmut, A. and Qin, D. and Fritzsche, S. and Nimo, J. and König, J. and Coscia, F.
Cell Systems 14 (11): 1002-1014. 15 November 2023

Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications.
Malinovska, L. and Cappelletti, V. and Kohler, D. and Piazza, I. and Tsai, T.H. and Pepelnjak, M. and Stalder, P. and Dörig, C. and Sesterhenn, F. and Elsässer, F. and Kralickova, L. and Beaton, N. and Reiter, L. and de Souza, N. and Vitek, O. and Picotti, P.
Nature Protocols 18 : 659-682. 16 March 2023

Replicative aging impedes stress-induced assembly of a key human protein disaggregase.
Mathangasinghe, Y. and Alberts, N. and Rosado, C.J. and Cox, D. and Payne, N.L. and Ormsby, A.R. and Alp, K.M. and Sakson, R. and Uthishtran, S. and Ruppert, T. and Arumugam, S. and Hatters, D.M. and Kampinga, H.H. and Nillegoda, N.B.
bioRxiv : 2022.06.25.497591. 8 January 2023

The IgCAM CAR regulates gap junction-mediated coupling on embryonic cardiomyocytes and affects their beating frequency.
Matthaeus, C. and Jüttner, R. and Gotthardt, M. and Rathjen, F.G.
Life 13 (1): 14. January 2023

The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Meier, M. and Gupta, M. and Akgül, S. and McDougall, M. and Imhof, T. and Nikodemus, D. and Reuten, R. and Moya-Torres, A. and To, V. and Ferens, F. and Heide, F. and Padilla-Meier, G.P. and Kukura, P. and Huang, W. and Gerisch, B. and Mörgelin, M. and Poole, K. and Antebi, A. and Koch, M. and Stetefeld, J.
Nature Communications 14 (1): 1226. 3 March 2023

Massively parallel identification of mRNA localization elements in primary cortical neurons.
Mendonsa, S. and von Kügelgen, N. and Dantsuji, S. and Ron, M. and Breimann, L. and Baranovskii, A. and Lödige, I. and Kirchner, M. and Fischer, M. and Zerna, N. and Bujanic, L. and Mertins, P. and Ulitsky, I. and Chekulaeva, M.
Nature Neuroscience 26 (3): 394-405. March 2023

Inflammatory cytokines associated with multiple sclerosis directly induce alterations of neuronal cytoarchitecture in human neurons.
Meyer-Arndt, L. and Kerkering, J. and Kuehl, T. and Gil Infante, A. and Paul, F. and Rosiewicz, K.S. and Siffrin, V. and Alisch, M.
Journal of Neuroimmune Pharmacology 18 (1-2): 145-159. June 2023

Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence.
Miller, D.C. and Lisowski, P. and Genehr, C. and Wanker, E.E. and Priller, J. and Prigione, A. and Diecke, S.
Stem Cell Research 68 : 103056. April 2023

CRISPR/Cas9 screen in gastric cancer patient-derived organoids reveals KDM1A-NDRG1 axis as a targetable vulnerability.
Mircetic, J. and Camgöz, A. and Abohawya, M. and Ding, L. and Dietzel, J. and Tobar, S.G. and Paszkowski-Rogacz, M. and Seidlitz, T. and Schmäche, T. and Mehnert, M.C. and Sidorova, O. and Weitz, J. and Buchholz, F. and Stange, D.E.
Small Methods 7 (6): e2201605. 20 June 2023

Lack of the Ig cell adhesion molecule BT-IgSF (IgSF11) induced behavioral changes in the open maze, water maze and resident intruder test.
Montag, D. and Pelz, L. and Rathjen, F.G.
PLoS ONE 18 (1): e0280133. 6 January 2023

CLK2 and CLK4 are regulators of DNA damage-induced NF-κB targeted by novel small molecule inhibitors.
Mucka, P. and Lindemann, P. and Bosco, B. and Willenbrock, M. and Radetzki, S. and Neuenschwander, M. and Brischetto, C. and von Kries, J.P. and Nazaré, M. and Scheidereit, C.
Cell Chemical Biology 30 (10): 1303-1312.e3. 19 October 2023

Role of TMEM100 in mechanically insensitive nociceptor un-silencing.
Nees, T.A. and Wang, N. and Adamek, P. and Zeitzschel, N. and Verkest, C. and La Porta, C. and Schaefer, I. and Virnich, J. and Balkaya, S. and Prato, V. and Morelli, C. and Begay, V. and Lee, Y.J. and Tappe-Theodor, A. and Lewin, G.R. and Heppenstall, P.A. and Taberner, F.J. and Lechner, S.G.
Nature Communications 14 (1): 1899. 5 April 2023

A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
Neuschulz, A. and Bakina, O. and Badillo Lisakowski, V. and Olivares-Chauvet, P. and Conrad, T. and Gotthardt, M. and Kettenmann, H. and Junker, J.P.
Molecular Systems Biology 19 (2): e11147. 10 February 2023

C/EBPβ-induced lymphoid-to-myeloid transdifferentiation emulates granulocyte-monocyte progenitor biology.
Nguyen, L.T. and Zimmermann, K. and Kowenz-Leutz, E. and Lim, R. and Hofstätter, M. and Mildner, A. and Leutz, A.
Stem Cell Reports 28 December 2023

Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.
Nurminen, A. and Jaatinen, S. and Taavitsainen, S. and Högnäs, G. and Lesluyes, T. and Ansari-Pour, N. and Tolonen, T. and Haase, K. and Koskenalho, A. and Kankainen, M. and Jasu, J. and Rauhala, H. and Kesäniemi, J. and Nikupaavola, T. and Kujala, P. and Rinta-Kiikka, I. and Riikonen, J. and Kaipia, A. and Murtola, T. and Tammela, T.L. and Visakorpi, T. and Nykter, M. and Wedge, D.C. and Van Loo, P. and Bova, G.S.
Genome Medicine 15 (1): 82. 12 October 2023

Daratumumab for the treatment of refractory ANCA-associated vasculitis.
Ostendorf, L. and Burns, M. and Wagner, D.L. and Enghard, P. and Amann, K. and Mei, H. and Eckardt, K.U. and Seelow, E. and Schreiber, A.
RMD Open 9 (1): e002742. 10 January 2023

Using PrISMa to reveal the interactome of the human claudins family.
Perez-Hernandez, D. and Suarez-Artiles, L. and Jones, M.S.O. and Dittmar, G.
STAR Protocols 4 (4): 102549. 15 December 2023

Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
Petrović, S. and Roske, Y. and Rami, B. and Phan, M.H.Q. and Panakova, D. and Heinemann, U.
Proceedings of the National Academy of Sciences of the United States of America 120 (4): e2208941120. 24 January 2023

SLC26A1 is a major determinant of sulfate homeostasis in humans.
Pfau, A. and López-Cayuqueo, K.I. and Scherer, N. and Wuttke, M. and Wernstedt, A. and González Fassrainer, D. and Smith, D.E. and van de Kamp, J.M. and Ziegeler, K. and Eckardt, K.U. and Luft, F.C. and Aronson, P.S. and Köttgen, A. and Jentsch, T.J. and Knauf, F.
Journal of Clinical Investigation 133 (3): e161849. 1 February 2023

H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma.
Phoyen, S. and Sanpavat, A. and Ma-on, C. and Stein, U. and Hirankarn, N. and Tangkijvanich, P. and Jindatip, D. and Whongsiri, P. and Boonla, C.
Heliyon 9 (12): e22589. December 2023

Autophagy orchestrates the crosstalk between cells and organs.
Piletic, K. and Alsaleh, G. and Simon, A.K.
EMBO Reports 24 (9): e57289. 6 September 2023

Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.
Proft, S. and Leiz, J. and Heinemann, U. and Seelow, D. and Schmidt-Ott, K.M. and Rutkiewicz, M.
BMC Genomics 24 (1): 736. 4 December 2023

Cryo-EM captures early ribosome assembly in action.
Qin, B. and Lauer, S.M. and Balke, A. and Vieira-Vieira, C.H. and Bürger, J. and Mielke, T. and Selbach, M. and Scheerer, P. and Spahn, C.M.T. and Nikolay, R.
Nature Communications 14 (1): 898. 17 February 2023

Retrotransposon: a versatile player in human preimplantation development and health.
Qu, Y. and Izsvák, Z. and Wang, J.
Life Medicine 2 (1): 1-3. February 2023

An integrate-and-fire approach to Ca(2+) signaling. Part II: Cumulative refractoriness.
Ramlow, L. and Falcke, M. and Lindner, B.
Biophysical Journal 122 (24): 4710-4729. 19 December 2023

An integrate-and-fire approach to Ca(2+) signaling. Part I: Renewal model.
Ramlow, L. and Falcke, M. and Lindner, B.
Biophysical Journal 122 (4): 713-736. 21 February 2023

The IgSF cell adhesion protein CLMP and congenital short bowel syndrome (CSBS).
Rathjen, F.G. and Jüttner, R.
International Journal of Molecular Sciences 24 (6): 5719. 16 March 2023

Long-read sequencing of diagnosis and post-therapy medulloblastoma reveals complex rearrangement patterns and epigenetic signatures.
Rausch, T. and Snajder, R. and Leger, A. and Simovic, M. and Giurgiu, M. and Villacorta, L. and Henssen, A.G. and Fröhling, S. and Stegle, O. and Birney, E. and Bonder, M.J. and Ernst, A. and Korbel, J.O.
Cell Genomics 3 (4): 100281. 12 April 2023

Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Richter, F.C. and Friedrich, M. and Kampschulte, N. and Piletic, K. and Alsaleh, G. and Zummach, R. and Hecker, J. and Pohin, M. and Ilott, N. and Guschina, I. and Wideman, S.K. and Johnson, E. and Borsa, M. and Hahn, P. and Morriseau, C. and Hammock, B.D. and Schipper, H.S. and Edwards, C.M and Zechner, R. and Siegmund, B. and Weidinger, C. and Schebb, N.H. and Powrie, F. and Simon, A.K.
EMBO Journal 42 (6): e112202. 15 March 2023

Mutational topography reflects clinical neuroblastoma heterogeneity.
Rodriguez-Fos, E. and Planas-Fèlix, M. and Burkert, M. and Puiggròs, M. and Toedling, J. and Thiessen, N. and Blanc, E. and Szymansky, A. and Hertwig, F. and Ishaque, N. and Beule, D. and Torrents, D. and Eggert, A. and Koche, R.P. and Schwarz, R.F. and Haase, K. and Schulte, J.H. and Henssen, A.G.
Cell Genomics 3 (10): 100402. 11 October 2023

HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
Rosiewicz, K.S. and Muinjonov, B. and Kunz, S. and Radbruch, H. and Chen, J. and Jüttner, R. and Kerkering, J. and Ucar, J. and Crowley, T. and Wielockx, B. and Paul, F. and Alisch, M. and Siffrin, V.
Glia 71 (8): 2024-2044. August 2023

TapA acts as specific chaperone in TasA filament formation by strand complementation.
Roske, Y. and Lindemann, F. and Diehl, A. and Cremer, N. and Higman, V.A. and Schlegel, B. and Leidert, M. and Driller, K. and Turgay, K. and Schmieder, P. and Heinemann, U. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 120 (17): e2217070120. 25 April 2023

The potential of cross-linking mass spectrometry in the development of protein-protein interaction modulators.
Ruwolt, M. and Piazza, I. and Liu, F.
Current Opinion in Structural Biology 82 : 102648. October 2023

Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.
Sandmann, C.L. and Schulz, J.F. and Ruiz-Orera, J. and Kirchner, M. and Ziehm, M. and Adami, E. and Marczenke, M. and Christ, A. and Liebe, N. and Greiner, J. and Schoenenberger, A. and Mücke, M.B. and Liang, N. and Moritz, R.L. and Sun, Z. and Deutsch, E.W. and Gotthardt, M. and Mudge, J.M. and Prensner, J.R. and Willnow, T.E. and Mertins, P. and van Heesch, S. and Hubner, N.
Molecular Cell 83 (6): 994-1011.e18. 16 March 2023

Proglucagon signalling in the rat dorsomedial hypothalamus - physiology and high-fat diet-mediated alterations.
Sanetra, A M. and Palus-Chramiec, K. and Chrobok, L. and Jeczmien-Lazur, J.S. and Klich, J.D. and Lewandowski, M.H.
Molecular and Cellular Neuroscience 126 : 103873. September 2023

Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis.
Schaupp, L. and Addante, A. and Völler, M. and Fentker, K. and Kuppe, A. and Bardua, M. and Duerr, J. and Piehler, L. and Röhmel, J. and Thee, S. and Kirchner, M. and Ziehm, M. and Lauster, D. and Haag, R. and Gradzielski, M. and Stahl, M. and Mertins, P. and Boutin, S. and Graeber, S.Y. and Mall, M.A.
European Respiratory Journal 62 (2): 2202153. 1 August 2023

Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N. and Cauchy, P. and Franke, V. and Giefing, M. and Fornes, O. and Vankadari, N. and Assi, S.A. and Costanza, M. and Weniger, M.A. and Akalin, A. and Anagnostopoulos, I. and Bukur, T. and Casarotto, M.G. and Damm, F. and Daumke, O. and Edginton-White, B. and Gebhardt, J.C.M. and Grau, M. and Grunwald, S. and Hansmann, M.L. and Hartmann, S. and Huber, L. and Kärgel, E. and Lusatis, S. and Noerenberg, D. and Obier, N. and Pannicke, U. and Fischer, A. and Reisser, A. and Rosenwald, A. and Schwarz, K. and Sundararaj, S. and Weilemann, A. and Winkler, W. and Xu, W. and Lenz, G. and Rajewsky, K. and Wasserman, W.W. and Cockerill, P.N. and Scheidereit, C. and Siebert, R. and Küppers, R. and Grosschedl, R. and Janz, M. and Bonifer, C. and Mathas, S.
Nature Communications 14 (1): 6947. 7 November 2023

COVID-19 and cellular senescence.
Schmitt, C.A. and Tchkonia, T. and Niedernhofer, L.J. and Robbins, P.D. and Kirkland, J.L. and Lee, S.
Nature Reviews Immunology 23 (4): 251-263. April 2023

Cantharidin and its analogue norcantharidin inhibit metastasis-inducing genes S100A4 and MACC1.
Schöpe, P.C. and Zinnow, V. and Ishfaq, M.A. and Smith, J. and Herrmann, P. and Shoemaker, R.H. and Walther, W. and Stein, U.
International Journal of Molecular Sciences 24 (2): 1179. 7 January 2023

A concise guide to choosing suitable gene expression systems for recombinant protein production.
Schütz, A. and Bernhard, F. and Berrow, N. and Buyel, J.F. and Ferreira-da-Silva, F. and Haustraete, J. and van den Heuvel, J. and Hoffmann, J.E. and de Marco, A. and Peleg, Y. and Suppmann, S. and Unger, T. and Vanhoucke, M. and Witt, S. and Remans, K.
STAR Protocols 4 (4): 102572. 15 December 2023

Novel multi-objective affinity approach allows to identify pH-specific μ-opioid receptor agonists.
Secker, C. and Fackeldey, K. and Weber, M. and Ray, S. and Gorgulla, C. and Schütte, C.
Journal of Cheminformatics 15 (1): 85. 19 September 2023

The polyphenol EGCG directly targets intracellular amyloid-β aggregates and promotes their lysosomal degradation.
Secker, C. and Motzny, A.Y. and Kostova, S. and Buntru, A. and Helmecke, L. and Reus, L. and Steinfort, R. and Brusendorf, L. and Boddrich, A. and Neuendorf, N. and Diez, L. and Schmieder, P. and Schulz, A. and Czekelius, C. and Wanker, E.E.
Journal of Neurochemistry 166 (2): 294-317. 18 July 2023

Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A. and Walter, S. and Markó, L. and McMurray, B.J. and Sunaga-Franze, D.Y. and Xu, M. and Zühlke, K. and Russwurm, M. and Bartolomaeus, T.U.P. and Langanki, R. and Qadri, F. and Heuser, A. and Patzak, A. and Forslund, S.K. and Bähring, S. and Borodina, T. and Persson, P.B. and Maass, P.G. and Bader, M. and Klussmann, E.
Kidney International 104 (2): 388-393. August 2023

GIPC1 regulates MACC1-driven metastasis.
Siegel, F. and Schmidt, H. and Juneja, M. and Smith, J. and Herrmann, P. and Kobelt, D. and Sharma, K. and Fichtner, I. and Walther, W. and Dittmar, G. and Volkmer, R. and Rathjen, F.G. and Schlag, P.M. and Stein, U.
Frontiers in Oncology 13 : 1280977. 8 December 2023

A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass.
Singh, M. and Kondrashkina, A. and Widmann, T.J. and Cortes, J.L. and Bansal, V. and Wang, J. and Römer, C. and Garcia-Canadas, M. and Garcia-Perez, J.L. and Hurst, L.D. and Izsvak, Z.
PLoS Biology 21 (6): e3002162. 20 June 2023

Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH.
Singh, M. and Kondraskhina, A.M. and Hurst, L.D. and Izsvák, Z.
Journal of Clinical Investigation 133 (14): e172278. 17 July 2023

Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.
Smith, E.J. and Sathasivam, K. and Landles, C. and Osborne, G.F. and Mason, M.A. and Gomez-Paredes, C. and Taxy, B.A. and Milton, R.E. and Ast, A. and Schindler, F. and Zhang, C. and Duan, W. and Wanker, E.E. and Bates, G.P.
Brain Communications 5 (1): fcad010. 20 January 2023

Urinary T cells identify renal antineutrophil cytoplasmic antibody-associated vasculitis and predict prognosis: a proof of concept study.
Sonnemann, J. and Klocke, J. and Bieringer, M. and Rousselle, A. and Eckardt, K.U. and Elitok, S. and Popovic, S. and Bachmann, S. and Kettritz, R. and Salama, A.D. and Enghard, P. and Schreiber, A.
Kidney International Reports 8 (4): 871-883. April 2023

Structure-based design of xanthine-imidazopyridines and -imidazothiazoles as highly potent and in vivo efficacious tryptophan hydroxylase inhibitors.
Specker, E. and Wesolowski, R. and Schütz, A. and Matthes, S. and Mallow, K. and Wasinska-Kalwa, M. and Winkler, L. and Oder, A. and Alenina, N. and Pleimes, D. and von Kries, J.P. and Heinemann, U. and Bader, M. and Nazaré, M.
Journal of Medicinal Chemistry 66 (21): 14866-14896. 9 November 2023

Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation.
Sporre, E. and Karlsen, J. and Schriever, K. and Asplund-Samuelsson, J. and Janasch, M. and Strandberg, L. and Karlsson, A. and Kotol, D. and Zeckey, L. and Piazza, I. and Syrén, P.O. and Edfors, F. and Hudson, E.P.
Communications Biology 6 (1): 947. 18 September 2023

Doxorubicin changes the spatial organization of the genome around active promoters.
Stefanova, M.E. and Ing-Simmons, E. and Stefanov, S. and Flyamer, I. and Dorado Garcia, H. and Schöpflin, R. and Henssen, A.G. and Vaquerizas, J.M. and Mundlos, S.
Cells 12 (15): 2001. 4 August 2023

Leveraging ligand affinity and properties: discovery of novel benzamide-type cereblon binders for the design of PROTACs.
Steinebach, C. and Bricelj, A. and Murgai, A. and Sosič, I. and Bischof, L. and Ng, Y.L.D. and Heim, C. and Maiwald, S. and Proj, M. and Voget, R. and Feller, F. and Košmrlj, J. and Sapozhnikova, V. and Schmidt, A. and Zuleeg, M.R. and Lemnitzer, P. and Mertins, P. and Hansen, F.K. and Gütschow, M. and Krönke, J. and Hartmann, M.D.
Journal of Medicinal Chemistry 66 (21): 14513-14543. 9 November 2023

Integrated proteomics unveils nuclear PDE3A2 as a regulator of cardiac myocyte hypertrophy.
Subramaniam, G. and Schleicher, K. and Kovanich, D. and Zerio, A. and Folkmanaite, M. and Chao, Y.C. and Surdo, N.C. and Koschinski, A. and Hu, J. and Scholten, A. and Heck, A.J.R and Ercu, M. and Sholokh, A. and Chan Park, K. and Klussmann, E. and Meraviglia, V. and Bellin, M. and Zanivan, S. and Hester, S. and Mohammed, S. and Zaccolo, M.
Circulation Research 132 (7): 828-848. 31 March 2023

Long-read sequencing reveals extensive DNA methylations in human gut phagenome contributed by prevalently phage-encoded methyltransferases.
Sun, C. and Chen, J. and Jin, M. and Zhao, X. and Li, Y. and Dong, Y. and Gao, N. and Liu, Z. and Bork, P. and Zhao, X.M. and Chen, W.H.
Advanced Science 10 (25): 2302159. 5 September 2023

The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest.
Szklarczyk, D. and Kirsch, R. and Koutrouli, M. and Nastou, K. and Mehryary, F. and Hachilif, R. and Gable, A.L. and Fang, T. and Doncheva, N.T. and Pyysalo, S. and Bork, P. and Jensen, L.J. and von Mering, C.
Nucleic Acids Research 51 (D1): D638-D646. 6 January 2023

Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
Torcal Garcia, G. and Kowenz-Leutz, E. and Tian, T.V and Klonizakis, A. and Lerner, J. and De Andres-Aguayo, L. and Sapozhnikova, V. and Berenguer, C. and Carmona, M.P. and Casadesus, M.V. and Bulteau, R. and Francesconi, M. and Peiro, S. and Mertins, P. and Zaret, K. and Leutz, A. and Graf, T.
eLife 12 : e83951. 27 June 2023

CORUM: the comprehensive resource of mammalian protein complexes-2022.
Tsitsiridis, G. and Steinkamp, R. and Giurgiu, M. and Brauner, B. and Fobo, G. and Frishman, G. and Montrone, C. and Ruepp, A.
Nucleic Acids Research 51 (D1): D539-D545. 6 January 2023

Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A. and Lahmann, I. and Nguyen, L.V.N. and Rost, B.R. and García-Pérez, A. and Lelievre, N. and Merritt-Garza, M.E. and Phan, H.C and Bassell, G.J. and Rossoll, W. and Diecke, S. and Kunz, S. and Schmitz, D. and Gouti, M.
Nature Communications 14 (1): 8043. 19 December 2023

Daratumumab as a novel treatment option in refractory ITP.
Vernava, I. and Schmitt, C.A.
Blood Cells Molecules and Diseases 99 : 102724. March 2023

Impact of first-line use of caplacizumab on treatment outcomes in immune thrombotic thrombocytopenic purpura.
Völker, L.A. and Kaufeld, J. and Balduin, G. and Merkel, L. and Kühne, L. and Eichenauer, D.A. and Osterholt, T. and Hägele, H. and Kann, M. and Grundmann, F. and Kolbrink, B. and Schulte, K. and Gäckler, A. and Kribben, A. and Boss, K. and Potthoff, S.A. and Rump, L.C. and Schmidt, T. and Mühlfeld, A.S. and Schulmann, K. and Hermann, M. and Gaedeke, J. and Sauerland, K. and Bramstedt, J. and Hinkel, U.P. and Miesbach, W. and Bauer, F. and Westhoff, T.H. and Bruck, H. and Buxhofer-Ausch, V. and Müller, T.J. and Wendt, R. and Harth, A. and Schreiber, A. and Seelow, E. and Tölle, M. and Gohlisch, C. and Bieringer, M. and Geuther, G. and Jabs, W.J. and Fischereder, M. and von Bergwelt-Baildon, A. and Schönermarck, U. and Knoebl, P. and Menne, J. and Brinkkoetter, P.T.
Journal of Thrombosis and Haemostasis 21 (3): 559-572. March 2023

Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia.
Wallach, T. and Raden, M. and Hinkelmann, L. and Brehm, M. and Rabsch, D. and Weidling, H. and Krüger, C. and Kettenmann, H. and Backofen, R. and Lehnardt, S.
Frontiers in Immunology 13 : 1066456. 13 January 2023

Getting to the root of branched ubiquitin chains: a review of current methods and functions.
Waltho, A. and Sommer, T.
Methods in Molecular Biology 2602 : 19-38. 2023

Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.
Wang, Z. and Shaabani, S. and Gao, X. and Ng, Y.L.D. and Sapozhnikova, V. and Mertins, P. and Krönke, J. and Dömling, A.
Nature Communications 14 (1): 8437. 19 December 2023

Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.
Watkins, T.B.K. and Colliver, E.C. and Huska, M.R. and Kaufmann, T.L. and Lim, E.L. and Duncan, C.B. and Haase, K. and Van Loo, P. and Swanton, C. and McGranahan, N. and Schwarz, R.F.
PLoS Computational Biology 19 (10): e1011379. 23 October 2023

PEDL+: Protein-centered relation extraction from PubMed at your fingertip.
Weber, L. and Barth, F. and Lorenz, L. and Konrath, F. and Huska, K. and Wolf, J. and Leser, U.
Bioinformatics 39 (11): btad603. November 2023

ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution.
Wu, J.Z. and Zeziulia, M. and Kwon, W. and Jentsch, T.J. and Grinstein, S. and Freeman, S.A.
Journal of Cell Biology 222 (6): e202208155. 5 June 2023

Consistency across multi-omics layers in a drug-perturbed gut microbial community.
Wuyts, S. and Alves, R. and Zimmermann-Kogadeeva, M. and Nishijima, S. and Blasche, S. and Driessen, M. and Geyer, P.E and Hercog, R. and Kartal, E. and Maier, L. and Müller, J.B. and Garcia Santamarina, S. and Schmidt, T.S.B. and Sevin, D.C. and Telzerow, A. and Treit, P.V. and Wenzel, T. and Typas, A. and Patil, K.R and Mann, M. and Kuhn, M. and Bork, P.
Molecular Systems Biology 19 (9): e11525. 12 September 2023

A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.
Xiong, E. and Popp, O. and Salomon, C. and Mertins, P. and Kocks, C. and Rajewsky, K. and Chu, V.T.
Frontiers in Immunology 13 : 1083119. 5 January 2023

Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Yan, S. and Schöpe, P.C. and Lewis, J. and Putzker, K. and Uhrig, U. and Specker, E. and von Kries, J.P. and Lindemann, P. and Omran, A. and Sanchez-Ibarra, H.E. and Unger, A. and Zischinsky, M.L. and Klebl, B. and Walther, W. and Nazaré, M. and Kobelt, D. and Stein, U.
Biomedicine & Pharmacotherapy 168 : 115698. December 2023

What do you most hope spatial molecular profiling will help us understand? Part 2.
Yanai, I. and Fertig, E.J. and Li, M. and Coscia, F. and Klughammer, J. and Nie, Q. and Chen, J. and Coskun, A.F.
Cell Systems 14 (7): 543-546. 19 July 2023

Molecular basis of ClC-6 function and its impairment in human disease.
Zhang, B. and Zhang, S. and Polovitskaya, M.M. and Yi, J. and Ye, B. and Li, R. and Huang, X. and Yin, J. and Neuens, S. and Balfroid, T. and Soblet, J. and Vens, D. and Aeby, A. and Li, X. and Cai, J. and Song, Y. and Li, Y. and Tartaglia, M. and Li, Y. and Jentsch, T.J. and Yang, M. and Liu, Z.
Science Advances 9 (41): eadg4479. 13 October 2023

Stable isotope-assisted untargeted metabolomics identifies ALDH1A1-driven erythronate accumulation in lung cancer cells.
Zhang, J. and Keibler, M.A. and Dong, W. and Ghelfi, J. and Cordes, T. and Kanashova, T. and Pailot, A. and Linster, C.L. and Dittmar, G. and Metallo, C.M. and Lautenschlaeger, T. and Hiller, K. and Stephanopoulos, G.
Biomedicines 11 (10): 2842. 19 October 2023

2022

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia, H. and Flórez, A.F. and Kreth, S. and Brückner, L.M. and Yildiz, U. and Gartlgruber, M. and Odoni, D.I. and Poschet, G. and Garbowicz, K. and Shao, C. and Klein, C. and Meier, J. and Zeisberger, P. and Nadler-Holly, M. and Ziehm, M. and Paul, F. and Burhenne, J. and Bell, E. and Shaikhkarami, M. and Würth, R. and Stainczyk, S.A. and Wecht, E.M. and Kreth, J. and Büttner, M. and Ishaque, N. and Schlesner, M. and Nicke, B. and Stresemann, C. and Llamazares-Prada, M. and Reiling, J.H. and Fischer, M. and Amit, I. and Selbach, M. and Herrmann, C. and Wölfl, S. and Henrich, K.O. and Höfer, T. and Trumpp, A. and Westermann, F.
Nature Cancer 3 (4): 471-485. 28 April 2022

Expanding the Huntington’s disease research toolbox; validated subdomain protein constructs for biochemical and structural investigation of huntingtin.
Alteen, M.G. and Deme, J.C. and Alvarez, C.P. and Loppnau, P. and Hutchinson, A. and Seitova, A. and Chandrasekaran, R. and Silva Ramos, E. and Secker, C. and Alqazzaz, M. and Wanker, E.E. and Lea, S.M. and Arrowsmith, C.H. and Harding, R.J.
bioRxiv : 2022.11.21.516512. 22 November 2022

The monocyte, a maestro in the tumor microenvironment (TME) of breast cancer.
Amer, H.T. and Stein, U. and El Tayebi, H.M.
Cancers 14 (21): 5460. 7 November 2022

Downregulation of odd-skipped related 2, a novel regulator of epithelial-mesenchymal transition, enables efficient somatic cell reprogramming.
Anh, L.P.H. and Nishimura, K. and Kuno, A. and Nguyen, T.L. and Kato, T. and Ohtaka, M. and Nakanishi, M. and Sugihara, E. and Sato, T.A. and Hayashi, Y. and Fukuda, A. and Hisatake, K.
Stem Cells 40 (4): 397-410. 29 April 2022

Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling.
Anton, S.E. and Kayser, C. and Maiellaro, I. and Nemec, K. and Möller, J. and Koschinski, A. and Zaccolo, M. and Annibale, P. and Falcke, M. and Lohse, M.J. and Bock, A.
Cell 185 (7): 1130-1142.e11. 31 March 2022

Immunohistochemical analysis of nicotinamide phosphoribosyltransferase expression in gastric and esophageal adenocarcinoma (AEG).
Arnold, A. and von Winterfeld, M. and Berg, E. and Hummel, M. and Rau, B. and Krenzien, F. and Stein, U. and Treese, C.
Gastrointestinal Disorders 4 (4): 333-340. 13 December 2022

Microglia form satellites with different neuronal subtypes in the adult murine central nervous system.
Bakina, O. and Kettenmann, H. and Nolte, C.
Journal of Neuroscience Research 100 (4): 1105-1122. April 2022

Unraveling the hidden temporal range of fast β(2)-adrenergic receptor mobility by time-resolved fluorescence.
Balakrishnan, A. and Hemmen, K. and Choudhury, S. and Krohn, J.H. and Jansen, K. and Friedrich, M. and Beliu, G. and Sauer, M. and Lohse, M.J. and Heinze, K.G.
Communications Biology 5 (1): 176. 28 February 2022

Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region.
Balasubramanian, S. and Andreani, M. and Goncalves Andrade, J. and Saha, T. and Sundaravinayagam, D. and Garzón, J. and Zhang, W. and Popp, O. and Hiraga, S. and Rahjouei, A. and Rosen, D.B. and Mertins, P. and Chait, B.T. and Donaldson, A.D. and Di Virgilio, M.
eLife 11 : e75047. 13 April 2022

Aurora kinase A is involved in controlling the localization of aquaporin-2 in renal principal cells.
Baltzer, S. and Bulatov, T. and Schmied, C. and Krämer, A. and Berger, B.T. and Oder, A. and Walker-Gray, R. and Kuschke, C. and Zühlke, K. and Eichhorst, J. and Lehmann, M. and Knapp, S. and Weston, J. and von Kries, J.P. and Süssmuth, R.D. and Klussmann, E.
International Journal of Molecular Sciences 23 (2): 763. 11 January 2022

Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A. and Malhan, D. and Dumbani, M. and Dahlmann, M. and Stein, U. and Relógio, A.
Cancers 14 (14): 3458. 16 July 2022

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G. and Blume, A. and Demirel, F.G. and Bulut, S. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 73 (1): 5-17. June 2022

Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation.
Baytek, G. and Popp, O. and Mertins, P. and Tursun, B.
Biotechniques 72 (5): 175-184. May 2022

Claudin-targeted suicide gene therapy for claudin-overexpressing tumor cells by using modified clostridium perfringens enterotoxin (CPE).
Beier, L.S. and Piontek, J. and Piontek, A. and Protze, J. and Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521 (3): 173-188. 23 June 2022

In memoriam: Stephen B. McMahon, PhD, FMedSci December 21, 1954 to October 9, 2021.
Bennett, D.L.H. and Bradbury, E.J. and Lewin, G.R. and Rice, A.S.C.
Pain 163 (3): 403-405. March 2022

Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells.
Berlak, M. and Tucker, E. and Dorel, M. and Winkler, A. and McGearey, A. and Rodriguez-Fos, E. and da Costa, B.M. and Barker, K. and Fyle, E. and Calton, E. and Eising, S. and Ober, K. and Hughes, D. and Koutroumanidou, E. and Carter, P. and Stankunaite, R. and Proszek, P. and Jain, N. and Rosswog, C. and Dorado-Garcia, H. and Molenaar, J.J. and Hubank, M. and Barone, G. and Anderson, J. and Lang, P. and Deubzer, H.E. and Künkele, A. and Fischer, M. and Eggert, A. and Kloft, C. and Henssen, A.G. and Boettcher, M. and Hertwig, F. and Blüthgen, N. and Chesler, L. and Schulte, J.H.
Molecular Cancer 21 (1): 126. 10 June 2022

Structural insights into crista junction formation by the Mic60-Mic19 complex.
Bock-Bierbaum, T. and Funck, K. and Wollweber, F. and Lisicki, E. and von der Malsburg, K. and von der Malsburg, A. and Laborenz, J. and Noel, J.K. and Hessenberger, M. and Jungbluth, S. and Bernert, C. and Kunz, S. and Riedel, D. and Lilie, H. and Jakobs, S. and van der Laan, M. and Daumke, O.
Science Advances 8 (35): eabo4946. 2 September 2022

The impact of membrane protein diffusion on GPCR signaling.
Boltz, H.H. and Sirbu, A. and Stelzer, N. and de Lanerolle, P. and Winkelmann, S. and Annibale, P.
Cells 11 (10): 1660. 17 May 2022

Taking out the trash: How misfolded proteins are removed from the endoplasmic reticulum.
Brodsky, J.L. and Engelman, D.M. and Hendershot, L.M. and Piana-Agostinetti, S. and Sommer, T.
Faculty Reviews 11 : 29. 5 October 2022

The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.
Buffenstein, R. and Amoroso, V. and Andziak, B. and Avdieiev, S. and Azpurua, J. and Barker, A.J. and Bennett, N.C. and Brieño-Enríquez, M.A. and Bronner, G.N. and Coen, C. and Delaney, M.A. and Dengler-Crish, C.M. and Edrey, Y.H. and Faulkes, C.G. and Frankel, D. and Friedlander, G. and Gibney, P.A. and Gorbunova, V. and Hine, C. and Holmes, M.M. and Jarvis, J.U.M. and Kawamura, Y. and Kutsukake, N. and Kenyon, C. and Khaled, W.T. and Kikusui, T. and Kissil, J. and Lagestee, S. and Larson, J. and Lauer, A. and Lavrenchenko, L.A. and Lee, A. and Levitt, J.B. and Lewin, G.R. and Lewis Hardell, K.N. and Lin, T.D. and Mason, M.J. and McCloskey, D. and McMahon, M. and Miura, K. and Mogi, K. and Narayan, V. and O'Connor, T.P. and Okanoya, K. and O'Riain, M.J. and Park, T.J. and Place, N.J. and Podshivalova, K. and Pamenter, M.E. and Pyott, S.J. and Reznick, J. and Ruby, J.G. and Salmon, A.B. and Santos-Sacchi, J. and Sarko, D.K. and Seluanov, A. and Shepard, A. and Smith, M. and Storey, K.B. and Tian, X. and Vice, E.N. and Viltard, M. and Watarai, Ak. and Wywial, E. and Yamakawa, M. and Zemlemerova, E.D. and Zions, M. and Smith, E.S.J.
Biological Reviews 97 (1): 115-140. February 2022

Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I. and Jaeschke, L. and Nimptsch, K. and Janke, J. and Herrmann, P. and Kobelt, D. and Kielstein, H. and Pischon, T. and Stein, U.
International Journal of Oncology 60 (2): 17. February 2022

Immune competence and spleen size scale with colony status in the naked mole-rat.
Bégay, V. and Cirovic, B. and Barker, A.J. and Klopffleisch, R. and Hart, D.W. and Bennett, N.C. and Lewin, G.R.
Open Biology 12 (4): 210292. 6 April 2022

AKAP18δ anchors and regulates CaMKII activity at phospholamban-SERCA2 and RYR.
Carlson, C.R. and Aronsen, J.M. and Bergan-Dahl, A. and Moutty, M.C. and Lunde, M. and Lunde, P.K. and Jarstadmarken, H. and Wanichawan, P. and Pereira, L. and Kolstad, T.R.S. and Dalhus, B. and Subramanian, H. and Hille, S. and Christensen, G. and Müller, O.J. and Nikolaev, V. and Bers, D.M. and Sjaastad, I. and Shen, X. and Louch, W.E. and Klussmann, E. and Sejersted, O.M.
Circulation Research 130 (1): 27-44. 7 January 2022

Towards the biogeography of prokaryotic genes.
Coelho, L.P. and Alves, R. and Del Río, Á.R. and Myers, P.N. and Cantalapiedra, C.P. and Giner-Lamia, J. and Schmidt, T.S. and Mende, D.R. and Orakov, A. and Letunic, I. and Hildebrand, F. and Van Rossum, T. and Forslund, S.K. and Khedkar, S. and Maistrenko, O.M. and Pan, S. and Jia, L. and Ferretti, P. and Sunagawa, S. and Zhao, X.M. and Nielsen, H.B. and Huerta-Cepas, J. and Bork, P.
Nature 601 (7892): 252-256. 13 January 2022

Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M. and Monks, A. and Harris, E.D. and Kobelt, D. and Osterland, M. and Khaireddine, F. and Herrmann, P. and Kemmner, W. and Burock, S. and Walther, W. and Shoemaker, R.H. and Stein, U.
Cancers 14 (1): 37. 2022

Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases.
Damerau, A. and Kirchner, M. and Pfeiffenberger, M. and Ehlers, L. and Do Nguyen, D.H. and Mertins, P. and Bartek, B. and Maleitzke, T. and Palmowski, Y. and Hardt, S. and Winkler, T. and Buttgereit, F. and Gaber, T.
Metabolic Engineering 72 : 116-132. July 2022

SPFH protein cage - one ring to rule them all.
Daumke, O. and Lewin, G.R.
Cell Research 32 (2): 117-118. February 2022

Functional repertoire convergence of distantly related eukaryotic plankton lineages abundant in the sunlit ocean.
Delmont, T.O. and Gaia, M. and Hinsinger, D.D. and Frémont, P. and Vanni, C. and Fernandez-Guerra, A. and Eren, A.M. and Kourlaiev, A. and d'Agata, L. and Clayssen, Q. and Villar, E. and Labadie, K. and Cruaud, C. and Poulain, J. and Da Silva, C. and Wessner, M. and Noel, B. and Aury, J.M. and de Vargas, C. and Bowler, C. and Karsenti, E. and Pelletier, E. and Wincker, P. and Jaillon, O.
Cell Genomics 2 (5): 100123. 11 May 2022

Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S. and Bittner, A. and Frick, M. and Kase, J. and Hoffmann, J. and Trenker, C. and Keller, U. and Bogner, C. and Hüttmann, A. and Dürig, J. and Janz, M. and Mathas, S. and Marks, R. and Krohn, U. and Na, I.K. and Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 63 (1): 84-92. January 2022

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.
Dorado Garcia, H. and Pusch, F. and Bei, Y. and von Stebut, J. and Ibáñez, G. and Guillan, K. and Imami, K. and Gürgen, D. and Rolff, J. and Helmsauer, K. and Meyer-Liesener, S. and Timme, N. and Bardinet, V. and Chamorro González, R. and MacArthur, I.C. and Chen, C.Y. and Schulz, J. and Wengner, A.M. and Furth, C. and Lala, B. and Eggert, A. and Seifert, G. and Hundsoerfer, P. and Kirchner, M. and Mertins, P. and Selbach, M. and Lissat, A. and Dubois, F. and Horst, D. and Schulte, J.H. and Spuler, S. and You, D. and Dela Cruz, F. and Kung, A.L. and Haase, K. and Di Virgilio, M. and Scheer, M. and Ortiz, M.V. and Henssen, A.G.
Nature Communications 13 (1): 4297. 25 July 2022

Simultaneous imaging and flow-cytometry-based detection of multiple fluorescent senescence markers in therapy-induced senescent cancer cells.
Dovjak, E. and Mairhofer, M. and Wöß, C. and Qi, J. and Fan, D.N.Y. and Schmitt, C.A. and Yu, Y.
Journal of Visualized Experiments (185): e63973. 12 July 2022

C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages.
Dörr, D. and Obermayer, B. and Weiner, J.M. and Zimmermann, K. and Anania, C. and Wagner, L.K. and Lyras, E.M. and Sapozhnikova, V. and Lara-Astiaso, D. and Prósper, F. and Lang, R. and Lupiáñez, D.G. and Beule, D. and Höpken, U.E. and Leutz, A. and Mildner, A.
Science Immunology 7 (75): eabj0140. September 2022

Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
Ebert, M.J. and Jerke, U. and Eulenberg-Gustavus, C. and Kling, L. and Jenne, D.E. and Kirchner, M. and Mertins, P. and Bieringer, M. and Elitok, S. and Eckardt, K.U. and Schreiber, A. and Salama, A.D. and Kettritz, R.
Journal of Clinical Investigation 132 (23): e160089. 1 December 2022

Gender differences in perceptions and attitudes of medical students towards neurosurgery: a german nationwide survey.
Efe, I.E. and Aliyeva, I. and Beyaztas, D. and Swiatek, V.M. and Esene, I.N. and Abdulrauf, S.I.
World Neurosurgery 163 : 96-103. July 2022

The anti-glucocorticoid receptor antibody clone 5E4: raising awareness of unspecific antibody binding.
Ehlers, L. and Kirchner, M. and Mertins, P. and Strehl, C. and Buttgereit, F. and Gaber, T.
International Journal of Molecular Sciences 23 (9): 5049. 2 May 2022

An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils.
Ellson, C.D. and Goretti Riça, I. and Kim, J.S. and Huang, Y.M.M. and Lim, D. and Mitra, T. and Hsu, A. and Wei, E.X. and Barrett, C.D. and Otterbein, L.E. and Hauser, C.J. and Wahl, M. and Delbrück, H. and Heinemann, U. and Oschkinat, H. and Chang, C.E.A. and Yaffe, M.B.
Journal of Molecular Biology 434 (9): 167533. 15 May 2022

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M. and Mücke, M.B. and Pallien, T. and Markó, L. and Sholokh, A. and Schächterle, C. and Aydin, A. and Kidd, A. and Walter, S. and Esmati, Y. and McMurray, B.J. and Lato, D.F. and Sunaga-Franze, D.Y. and Dierks, P.H. and Flores, B.I.M. and Walker-Gray, R. and Gong, M. and Merticariu, C. and Zühlke, K. and Russwurm, M. and Liu, T. and Batolomaeus, T.U.P. and Pautz, S. and Schelenz, S. and Taube, M. and Napieczynska, H. and Heuser, A. and Eichhorst, J. and Lehmann, M. and Miller, D.C. and Diecke, S. and Qadri, F. and Popova, E. and Langanki, R. and Movsesian, M.A. and Herberg, F.W. and Forslund, S.K. and Müller, D.N. and Borodina, T. and Maass, P.G. and Bähring, S. and Hübner, N. and Bader, M. and Klussmann, E.
Circulation 146 (23): 1758-1778. 6 December 2022

Evidence for recombinant GRP78, CALR, PDIA3 and GPI as mediators of genetic instability in human CD34+ cells.
Fabarius, A. and Samra, V. and Drews, O. and Mörz, H. and Bierbaum, M. and Darwich, A. and Weiss, C. and Brendel, S. and Kleiner, H. and Seifarth, W. and Greffrath, W. and Hofmann, W.K. and Schmitt, C.A. and Popp, H.D.
Cancers 14 (12): 2883. 11 June 2022

A cFLIP-flop switch for senolysis.
Fan, D.N.Y. and Schmitt, C.A.
Nature Cancer 3 (11): 1279-1281. November 2022

One gene - two proteins: the C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria.
Fasciani, I. and Petragnano, F. and Wang, Z. and Edwards, R. and Telugu, N. and Pietrantoni, I. and Zauber, H. and Rossi, M. and Zabel, U. and Grieben, M. and Terzenidou, M.E. and Di Gregorio, J. and Pellegrini, C. and Santini, S. and Taddei, A.R. and Poehl, B. and Aringhieri, S. and Aloisi, G. and Marampon, F. and Roman, A. and Diecke, S. and Flati, V. and Giorgi, F. and Amicarelli, F. and Tobin, A.B. and Scarselli, M. and Tokatlidis, K. and Lohse, M.J. and Maggio, R. and Annibale, P.
bioRxiv : 2021.04.13.438299. 26 February 2022

Editorial: The long road to building a head: smooth travels and accidents on the journey from patterning via morphogenesis to phenotype.
Feistel, K. and Hammes, A. and Sela-Donenfeld, D.
Frontiers in Cell and Developmental Biology 10 : 895497. 25 April 2022

C. difficile is overdiagnosed in adults and a commensal in infants.
Ferretti, P. and Wirbel, J. and Maistrenko, O.M. and Van Rossum, T. and Alves, R. and Fullam, A. and Akanni, W. and Schudoma, C. and Schwarz, A. and Thielemann, R. and Thomas, L. and Kuhn, M. and Zeller, G. and Schmidt, T.S.B. and Bork, P.
bioRxiv : 2022.02.16.480740v1. 18 February 2022

The SCF/KIT axis in human mast cells: capicua acts as potent KIT repressor and ERK predominates PI3K.
Franke, K. and Kirchner, M. and Mertins, P. and Zuberbier, T. and Babina, M.
Allergy 77 (11): 3337-3349. November 2022

Modeling IP(3) induced Ca(2+) signaling based on its interspike interval statistics.
Friedhoff, V.N. and Falcke, M.
bioRxiv : 2022.12.20.521161. 20 December 2022

Dataset debt in biomedical language modeling.
Fries, J.A. and Seelam, N. and Altay, G. and Weber, L. and Kang, M. and Datta, D. and Su, R. and Garda, S. and Wang, B. and Ott, S. and Samwald, M. and Kusa, W.
In: 2022 Challenges and Perspectives in Creating Large Language Models, 27 May 2022, Virtual, Dublin. May 2022

A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts.
Gabelich, J.A. and Grützke, J. and Kirscht, F. and Popp, O. and Matz, J.M. and Dittmar, G. and Rug, M. and Ingmundson, A.
PLoS Pathogens 18 (9): e1010846. 20 September 2022

Bruton's tyrosine kinase inhibitors in multiple sclerosis: pioneering the path towards treatment of progression?
Geladaris, A. and Torke, S. and Weber, M.S.
CNS drugs 36 (10): 1019-1030. October 2022

The role of intraspinal sensory neurons in the control of quadrupedal locomotion.
Gerstmann, K. and Jurčić, N. and Blasco, E. and Kunz, S. and de Almeida Sassi, F. and Wanaverbecq, N. and Zampieri, N.
Current Biology 32 (11): 2442-2453. 6 June 2022

An unusual aspartic acid cluster in the reovirus attachment fiber s1 mediates stability at low pH and preserves trimeric organization.
Glorani, G. and Ruwolt, M. and Holton, N. and Loll, B. and Neu, U.
Journal of Virology 96 (8): e0033122. April 2022

Fluorescence spectroscopy of low-level endogenous β-adrenergic receptor expression at the plasma membrane of differentiating human iPSC-derived cardiomyocytes.
Gmach, P. and Bathe-Peters, M. and Telugu, N. and Miller, D.C. and Annibale, P.
International Journal of Molecular Sciences 23 (18): 10405. 8 September 2022

Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O. and Zincke, F. and Eckert, A. and Kobelt, D. and Preissner, S. and Liebeskind, J.M. and Gunkel, N. and Putzker, K. and Lewis, J. and Preissner, S. and Kortüm, B. and Walther, W. and Mura, K. and Bourne, P.E. and Stein, U. and Preissner, R.
Clinical and Translational Medicine 12 (2): e726. 20 February 2022

Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.
Greco, T.M. and Secker, C. and Silva Ramos, E. and Federspiel, J.D. and Liu, J.P. and Perez, A.M. and Al-Ramahi, I. and Cantle, J.P. and Carroll, J.B. and Botas, J. and Zeitlin, S.O. and Wanker, E.E. and Cristea, I.M.
Cell Systems 13 (4): 304-320.e5. 22 April 2022

Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients.
Grunow, J.J. and Reiher, K. and Carbon, N.M. and Engelhardt, L.J. and Mai, K. and Koch, S. and Schefold, J.C. and Z'Graggen, W. and Schaller, S.J. and Fielitz, J. and Spranger, J. and Weber-Carstens, S. and Wollersheim, T.
Critical Care 26 (1): 237. 3 August 2022

MACC1-dependent antitumor effect of curcumin in colorectal cancer.
Güllü, N. and Smith, J. and Herrmann, P. and Stein, U.
Nutrients 14 (22): 4792. 12 November 2022

The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Günes Günsel, G. and Conlon, T.M. and Jeridi, A. and Kim, R. and Ertüz, Z. and Lang, N.J. and Ansari, M. and Novikova, M. and Jiang, D. and Strunz, M. and Gaianova, M. and Hollauer, C. and Gabriel, C. and Angelidis, I. and Doll, S. and Pestoni, J.C. and Edelmann, S.L. and Kohlhepp, M.S. and Guillot, A. and Bassler, K. and Van Eeckhoutte, H.P. and Kayalar, Ö. and Konyalilar, N. and Kanashova, T. and Rodius, S. and Ballester-López, C. and Genes Robles, C.M. and Smirnova, N. and Rehberg, M. and Agarwal, C. and Krikki, I. and Piavaux, B. and Verleden, S.E. and Vanaudenaerde, B. and Königshoff, M. and Dittmar, G. and Bracke, K.R. and Schultze, J.L. and Watz, H. and Eickelberg, O. and Stoeger, T. and Burgstaller, G. and Tacke, F. and Heissmeyer, V. and Rinkevich, Y. and Bayram, H. and Schiller, H.B. and Conrad, M. and Schneider, R. and Yildirim, A.Ö.
Nature Communications 13 (1): 1303. 14 March 2022

A molecularly characterized preclinical platform of subcutaneous renal cell carcinoma (RCC) patient-derived xenograft models to evaluate novel treatment strategies.
Gürgen, D. and Becker, M. and Dahlmann, M. and Flechsig, S. and Schaeffeler, E. and Büttner, F.A. and Schmees, C. and Bohnert, R. and Bedke, J. and Schwab, M. and Wendler, J.J. and Schostak, M. and Jandrig, B. and Walther, W. and Hoffmann, J.
Frontiers in Oncology 12 : 889789. 21 June 2022

Rational design of highly potent, selective, and bioavailable SGK1 protein kinase inhibitors for the treatment of osteoarthritis.
Halland, N. and Schmidt, F. and Weiss, T. and Li, Z. and Czech, J. and Saas, J. and Ding-Pfennigdorff, D. and Dreyer, M.K. and Strübing, C. and Nazare, M.
Journal of Medicinal Chemistry 65 (2): 1567-1584. 27 January 2022

A critical period of translational control during brain development at codon resolution.
Harnett, D. and Ambrozkiewicz, M.C. and Zinnall, U. and Rusanova, A. and Borisova, E. and Drescher, A.N. and Couce-Iglesias, M. and Villamil, G. and Dannenberg, R. and Imami, K. and Münster-Wandowski, A. and Fauler, B. and Mielke, T. and Selbach, M. and Landthaler, M. and Spahn, C.M.T. and Tarabykin, V. and Ohler, U. and Kraushar, M.L.
Nature Structural & Molecular Biology 29 (12): 1277-1290. December 2022

Shedding light on ecDNA behavior using CRISPR-based live-cell imaging.
Henssen, A.G.
Cancer Discovery 12 (2): 293-295. 9 February 2022

Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors.
Heynen, G.J.J.E. and Lisek, K. and Vogel, R. and Wulf-Goldenberg, A. and Alcaniz, J. and Montaudon, E. and Marangoni, E. and Birchmeier, W.
Breast Cancer Research 24 (1): 23. 1 April 2022

A novel AQP2 sequence variant causing aquaporin-2 retention in the cytoplasm and autosomal dominant nephrogenic diabetes insipidus.
Hinrichs, G.R. and Baltzer, S. and Pallien, T. and Svenningsen, P. and Dalgaard, E.B. and Hertz, J.M. and Bistrup, C. and Jensen, B.L. and Klussmann, E.
Kidney International Reports 7 (10): 2289-2294. October 2022

Uncoupling the excitatory amino acid transporter 2 from its C-terminal interactome restores synaptic glutamate clearance at corticostriatal synapses and alleviates mutant huntingtin-induced hypokinesia.
Hirschberg, S. and Dvorzhak, A. and Rasooli-Nejad, S.M.A. and Angelov, S. and Kirchner, M. and Mertins, P. and Lättig-Tünnemann, G. and Harms, C. and Schmitz, D. and Grantyn, R.
Frontiers in Cellular Neuroscience 15 : 792652. 31 January 2022

Mechanisms of spermidine-induced autophagy and geroprotection.
Hofer, S.J. and Simon, A.K. and Bergmann, M. and Eisenberg, T. and Kroemer, G. and Madeo, F.
Nature Aging 2 (12): 1112-1129. December 2022

MACC1-induced collective migration is promoted by proliferation rather than single cell biomechanics.
Hohmann, T. and Hohmann, U. and Dahlmann, M. and Kobelt, D. and Stein, U. and Dehghani, F.
Cancers 14 (12): 2857. 9 June 2022

Microglia/macrophage derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model.
Huang, Y. and Motta, E. and Nanvuma, C. and Kuhrt, L.D. and Yuan, Y. and Xia, P. and Lubas, M. and Zhu, S. and Schnauss, M. and Qazi, N. and Hu, F. and Zhang, H. and Lei, T. and Synowitz, M. and Flüh, C. and Kettenmann, H.
Cell Reports 39 (2): 110670. 12 April 2022

Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
Hung, K.L. and Luebeck, J. and Dehkordi, S.R. and Colón, C.I. and Li, R. and Wong, I.T.L. and Coruh, C. and Dharanipragada, P. and Lomeli, S.H. and Weiser, N.E. and Moriceau, G. and Zhang, X. and Bailey, C. and Houlahan, K.E. and Yang, W. and González, R.C. and Swanton, C. and Curtis, C. and Jamal-Hanjani, M. and Henssen, A.G. and Law, J.A. and Greenleaf, W.J. and Lo, R.S. and Mischel, P.S. and Bafna, V. and Chang, H.Y.
Nature Genetics 54 (11): 1746–1754. November 2022

Physical performance and non-esterified fatty acids in men and women after transcatheter aortic valve implantation (TAVI).
Härdrich, M. and Haase-Fielitz, A. and Fielitz, J. and Boschmann, M. and Pivovarova-Ramich, O. and Pfeiffer, A.F.H. and Rudovich, N. and Weylandt, K.H. and Butter, C.
Nutrients 14 (1): 203. 2 January 2022

Evaluation of pharmacological rescue of melanocortin-4 receptor nonsense mutations by aminoglycoside.
Höpfner, F. and Paisdzior, S. and Reininghaus, N. and Sohail, I. and Scheerer, P. and Annibale, P. and Biebermann, H. and Kühnen, P.
Life 12 (11): 1793. 5 November 2022

Monitoring mitochondrial translation by pulse SILAC.
Imami, K. and Selbach, M. and Ishihama, Y.
bioRxiv : 2021.01.31.428997. 8 June 2022

H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2(+) patients with diffuse midline glioma.
Immisch, L. and Papafotiou, G. and Popp, O. and Mertins, P. and Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 10 (10): e005535. 27 October 2022

Analyses of circRNA expression throughout the light-dark cycle reveal a strong regulation of (Cdr1as), associated with light entrainment in the SCN.
Ivanov, A. and Mattei, D. and Radscheit, K. and Compagnion, A.C. and Pett, J.P. and Herzel, H.P. and Paolicelli, R.C. and Piwecka, M. and Meyer, U. and Beule, D.
International Journal of Molecular Sciences 23 (20): 12347. October 2022

Targeting cathepsin C in PR3-ANCA vasculitis.
Jerke, U. and Eulenberg-Gustavus, C. and Rousselle, A. and Nicklin, P. and Kreideweiss, S. and Grundl, M.A. and Eickholz, P. and Nickles, K. and Schreiber, A. and Korkmaz, B. and Kettritz, R.
Journal of the American Society of Nephrology 33 (5): 936-947. May 2022

DNA methylation-based classification of sinonasal tumors.
Jurmeister, P. and Glöß, S. and Roller, R. and Leitheiser, M. and Schmid, S. and Mochmann, L.H. and Payá Capilla, E. and Fritz, R. and Dittmayer, C. and Friedrich, C. and Thieme, A. and Keyl, P. and Jarosch, A. and Schallenberg, S. and Bläker, H. and Hoffmann, I. and Vollbrecht, C. and Lehmann, A. and Hummel, M. and Heim, D. and Haji, M. and Harter, P. and Englert, B. and Frank, S. and Hench, J. and Paulus, W. and Hasselblatt, M. and Hartmann, W. and Dohmen, H. and Keber, U. and Jank, P. and Denkert, C. and Stadelmann, C. and Bremmer, F. and Richter, A. and Wefers, A. and Ribbat-Idel, J. and Perner, S. and Idel, C. and Chiariotti, L. and Della Monica, R. and Marinelli, A. and Schüller, U. and Bockmayr, M. and Liu, J. and Lund, V.J. and Forster, M. and Lechner, M. and Lorenzo-Guerra, S.L. and Hermsen, M. and Johann, P.D. and Agaimy, A. and Seegerer, P. and Koch, A. and Heppner, F. and Pfister, S.M. and Jones, D.T.W. and Sill, M. and von Deimling, A. and Snuderl, M. and Müller, K.R. and Forgó, E. and Howitt, B.E. and Mertins, P. and Klauschen, F. and Capper, D.
Nature Communications 13 (1): 7148. 28 November 2022

Small molecule inhibitors for hepatocellular carcinoma: advances and challenges.
Kamal, M.A. and Mandour, Y.M. and Abd El-Aziz, M.K. and Stein, U. and El Tayebi, H.M.
Molecules 27 (17): 5537. 1 September 2022

A faecal microbiota signature with high specificity for pancreatic cancer.
Kartal, E. and Schmidt, T.S.B. and Molina-Montes, E. and Rodríguez-Perales, S. and Wirbel, J. and Maistrenko, O.M. and Akanni, W.A. and Alashkar Alhamwe, B. and Alves, R.J. and Carrato, A. and Erasmus, H.P. and Estudillo, L. and Finkelmeier, F. and Fullam, A. and Glazek, A.M. and Gómez-Rubio, P. and Hercog, R. and Jung, F. and Kandels, S. and Kersting, S. and Langheinrich, M. and Márquez, M. and Molero, X. and Orakov, A. and Van Rossum, T. and Torres-Ruiz, R. and Telzerow, A. and Zych, K. and Benes, V. and Zeller, G. and Trebicka, J. and Real, F.X. and Malats, N. and Bork, P.
Gut 71 (7): 1359-1372. 7 June 2022

Identification of early neurodegenerative pathways in progressive multiple sclerosis.
Kaufmann, M. and Schaupp, A.L. and Sun, R. and Coscia, F. and Dendrou, C.A. and Cortes, A. and Kaur, G. and Evans, H.G. and Mollbrink, A. and Navarro, J.F. and Sonner, J.K. and Mayer, C. and DeLuca, G.C. and Lundeberg, J. and Matthews, P.M. and Attfield, K.E. and Friese, M.A. and Mann, M. and Fugger, L.
Nature Neuroscience 25 (7): 944-955. July 2022

Real-time measurements of intracellular cAMP gradients using FRET-based cAMP nanorulers.
Kayser, C. and Lohse, M.J. and Bock, A.
Methods in Molecular Biology 2483 : 1-13. 2022

Glial cells: neuroglia.
Kettenmann, H. and Verkhratsky, A.
In: Neuroscience in the 21st century: from basic to clinical (3rd ed.). Springer Nature, Cham, 825-860. ISBN 978-3-030-88831-2 2022

Complement is complimentary in membranous nephropathy.
Kettritz, R. and Schreiber, A.
Journal of the American Society of Nephrology 33 (9): 1631-1633. September 2022

Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes.
Khedkar, S. and Smyshlyaev, G. and Letunic, I. and Maistrenko, O.M. and Coelho, L.P. and Orakov, A. and Forslund, S.K. and Hildebrand, F. and Luetge, M. and Schmidt, T.S.B. and Barabas, O. and Bork, P.
Nucleic Acids Research 50 (6): 3155-3168. 8 April 2022

Proteolytic cleavage of the extracellular domain affects signaling of parathyroid hormone 1 receptor.
Klenk, C. and Hommers, L. and Lohse, M.J.
Frontiers in Endocrinology 13 : 839351. 22 February 2022

Proteolytic cleavage of the extracellular domain affects signaling of parathyroid hormone receptor 1.
Klenk, C. and Hommers, L. and Lohse, M.J.
bioRxiv : 2021.12.16.472984. 19 January 2022

Hidden agenda - the involvement of endoplasmic reticulum stress and unfolded protein response in inflammation-induced muscle wasting.
Kny, M. and Fielitz, J.
Frontiers in Immunology 13 : 878755. 9 May 2022

A brief introduction to current cancer gene therapy.
Kobelt, D. and Pahle, J. and Walther, W.
Methods in Molecular Biology 2521 (3): 1-21. 23 June 2022

Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.
Kofla, G. and Radecke, C. and Frentsch, M. and Walther, W. and Stintzing, S. and Riess, H. and Bullinger, L. and Na, I.K.
OncoImmunology 11 (1): 2068109. 25 April 2022

Functional indications for transposase domestications - characterization of the human piggyBac transposase derived (PGBD) activities.
Kolacsek, O. and Wachtl, G. and Fóthi, Á. and Schamberger, A. and Sándor, S. and Pergel, E. and Varga, N. and Raskó, T. and Izsvák, Z. and Apáti, Á. and Orbán, T.I.
Gene 834 : 146609. 5 August 2022

Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis.
Kortüm, B. and Radhakrishnan, H. and Zincke, F. and Sachse, C. and Burock, S. and Keilholz, U. and Dahlmann, M. and Walther, W. and Dittmar, G. and Kobelt, D. and Stein, U.
Oncogene 41 (39): 4446-4458. 23 September 2022

GMP-grade manufacturing and quality control of a non-virally engineered advanced therapy medicinal product for personalized treatment of age-related macular degeneration.
Kropp, M. and Harmening, N. and Bascuas, T. and Johnen, S. and De Clerck, E. and Fernández, V. and Ronchetti, M. and Cadossi, R. and Zanini, C. and Scherman, D. and Ivics, Z. and Marie, C. and Izsvák, Z. and Thumann, G.
Biomedicines 10 (11): 2777. November 2022

Paracrine interleukin 6 induces cerebral remodeling at early stages after unilateral common carotid artery occlusion in mice.
Kuffner, M.T.C. and Koch, S.P and Kirchner, M. and Mueller, S. and Lips, J. and An, J. and Mertins, P. and Dirnagl, U. and Endres, M. and Boehm-Sturm, P. and Harms, C. and Hoffmann, C.J.
Frontiers in Cardiovascular Medicine 8 : 805095. 27 January 2022

Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses.
Kunath, B.J. and Hickl, O. and Queirós, P. and Martin-Gallausiaux, C. and Lebrun, L.A. and Halder, R. and Laczny, C.C. and Schmidt, T.S.B. and Hayward, M.R. and Becher, D. and Heintz-Buschart, A. and de Beaufort, C. and Bork, P. and May, P. and Wilmes, P.
Microbiome 10 (1): 243. 28 December 2022

The evolutionary dynamics of extrachromosomal DNA in human cancers.
Lange, J.T. and Rose, J.C. and Chen, C.Y. and Pichugin, Y. and Xie, L. and Tang, J. and Hung, K.L. and Yost, K.E. and Shi, Q. and Erb, M.L. and Rajkumar, U. and Wu, S. and Taschner-Mandl, S. and Bernkopf, M. and Swanton, C. and Liu, Z. and Huang, W. and Chang, H.Y. and Bafna, V. and Henssen, A.G. and Werner, B. and Mischel, P.S.
Nature Genetics 54 (10): 1527-1533. October 2022

A flexible tool to correct superimposed mass isotopologue distributions in GC-APCI-MS flux experiments.
Langenhan, J. and Jaeger, C. and Baum, K. and Simon, M. and Lisec, J.
Metabolites 12 (5): 408. 29 April 2022

Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors.
Li, C. and Wang, H. and Gil, S. and Germond, A. and Fountain, C. and Baldessari, A. and Kim, J. and Liu, Z. and Georgakopoulou, A. and Radtke, S. and Raskó, T. and Pande, A. and Chiang, C. and Chin, E. and Yannaki, E. and Izsvak, Z. and Papayannopoulou, T. and Kiem, H.P. and Lieber, A.
Molecular Therapy - Methods and Clinical Development 24 : 127-141. 10 March 2022

A weak-labelling and deep learning approach for in-focus object segmentation in 3D widefield microscopy.
Li, R. and Kudryashev, M. and Yakimovich, A.
Research Square : rs.3.rs-2362531/v1. 20 December 2022

Structural basis of phosphatidylinositol 3-kinase C2α function.
Lo, W.T. and Zhang, Y. and Vadas, O. and Roske, Y. and Gulluni, F. and De Santis, M.C. and Zagar, A.V. and Stephanowitz, H. and Hirsch, E. and Liu, F. and Daumke, O. and Kudryashev, M. and Haucke, V.
Nature Structural & Molecular Biology 29 (3): 218-228. March 2022

Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.
Lorenz, C. and Zink, A. and Henke, M.T. and Staege, S. and Mlody, B. and Bünning, M. and Wanker, E. and Diecke, S. and Schuelke, M. and Prigione, A.
Stem Cell Research 61 : 102742. May 2022

Tongue immune compartment analysis reveals spatial macrophage heterogeneity.
Lyras, E.M. and Zimmermann, K. and Wagner, L.K. and Dörr, D. and Klose, C.S.N and Fischer, C. and Jung, S. and Yona, S. and Hovav, A.H. and Stenzel, W. and Dommerich, S. and Conrad, T. and Leutz, A. and Mildner, A.
eLife 11 : 77490. 24 June 2022

Renal deletion of LRRC8/VRAC channels induces proximal tubulopathy.
López-Cayuqueo, K.I. and Planells-Cases, R. and Pietzke, M. and Oliveras, A. and Kempa, S. and Bachmann, S. and Jentsch, T.J.
Journal of the American Society of Nephrology 33 (8): 1528-1545. August 2022

Impact of metabolic stress induced by diets, aging and fasting on tissue oxygen consumption.
Mackert, O. and Wirth, E.K. and Sun, R. and Winkler, J. and Liu, A. and Renko, K. and Kunz, S. and Spranger, J. and Brachs, S.
Molecular Metabolism 64 : 101563. October 2022

Forebrain development - an intricate balance decides between health and disease.
Mamo, T.M. and Hammes, A.
Neuroforum 28 (4): 233-243. 25 November 2022

In vitro Kinase-to-Phosphosite database (iKiP-DB) predicts kinase activity in phosphoproteomic datasets.
Mari, T. and Mösbauer, K. and Wyler, E. and Landthaler, M. and Drosten, C. and Selbach, M.
Journal of Proteome Research 21 (6): 1575-1587. 3 June 2022

Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F. and Jerke, U. and Rolle, S. and Daumke, O. and Kettritz, R.
Journal of Biological Chemistry 298 (3): 101598. March 2022

Molecular and functional characterization of BDNF-overexpressing human retinal pigment epithelial cells established by sleeping beauty transposon-mediated gene transfer.
Mattern, L. and Otten, K. and Miskey, C. and Fuest, M. and Izsvák, Z. and Ivics, Z. and Walter, P. and Thumann, G. and Johnen, S.
International Journal of Molecular Sciences 23 (21): 12982. 1 November 2022

Physiological functions of intracellular protein degradation.
McShane, E. and Selbach, M.
Annual Review of Cell and Developmental Biology 38 : 241-262. October 2022

Compound interaction screen on a photoactivatable cellulose membrane (CISCM) identifies drug targets.
Melder, F.T. and Lindemann, P. and Welle, A. and Trouillet, V. and Heißler, S. and Nazaré, M. and Selbach, M.
ChemMedChem 17 (19): e202200346. 6 October 2022

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A. and Sprink, T. and Noel, J.K. and Vázquez-Sarandeses, E. and van Hoorn, C. and Mohd, S. and Loerke, J. and Spahn, C.M.T. and Daumke, O.
Nature Communications 13 (1): 7641. 10 December 2022

Generation of induced pluripotent stem cells from three individuals with Huntington's disease.
Miller, D.C. and Lisowski, P. and Lickfett, S. and Mlody, B. and Bünning, M. and Genehr, C. and Ulrich, C. and Wanker, E.E. and Diecke, S. and Priller, J. and Prigione, A.
Stem Cell Research 65 : 102976. December 2022

Suicide nanoplasmids coding for ribosome-inactivating proteins.
Mitdank, H. and Tröger, M. and Sonntag, A. and Shirazi, N.A. and Woith, E. and Fuchs, H. and Kobelt, D. and Walther, W. and Weng, A.
European Journal of Pharmaceutical Sciences 170 : 106107. 1 March 2022

Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis.
Moshkovits, I. and Kaminitz, A. and Reuveni, D. and Pasmanik-Chor, M. and Brazowski, E. and Mildner, A. and Leutz, A. and Zigmond, E.
Immunity, inflammation and disease 10 (11): e728. November 2022

Deep Visual Proteomics defines single-cell identity and heterogeneity.
Mund, A. and Coscia, F. and Kriston, A. and Hollandi, R. and Kovács, F. and Brunner, A.D. and Migh, E. and Schweizer, L. and Santos, A. and Bzorek, M. and Naimy, S. and Rahbek-Gjerdrum, L.M. and Dyring-Andersen, B. and Bulkescher, J. and Lukas, C. and Eckert, M.A. and Lengyel, E. and Gnann, C. and Lundberg, E. and Horvath, P. and Mann, M.
Nature Biotechnology 40 (8): 1231-1240. August 2022

The molecular mechanism and physiological role of silent nociceptor activation.
Nees, T.A. and Wang, N. and Adamek, P. and Verkest, C. and Schaefer, I. and Virnich, J. and Balkaya, S. and Prato, V. and Morelli, C. and Zeitzschel, N. and Begay, V. and Lee, Y.J. and Lewin, G.R. and Heppenstall, P.A. and Taberner, F.J. and Lechner, S.G.
bioRxiv : 2022.04.07.486730. 19 October 2022

Functional modulation of PTH1R activation and signaling by RAMP2.
Nemec, K. and Schihada, H. and Kleinau, G. and Zabel, U. and Grushevsky, E.O. and Scheerer, P. and Lohse, M.J. and Maiellaro, I.
Proceedings of the National Academy of Sciences of the United States of America 119 (32): e2122037119. 9 August 2022

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D. and Ramberger, E. and Bohl, S.R. and Dolnik, A. and Steinebach, C. and Conrad, T. and Müller, S. and Popp, O. and Kull, M. and Haji, M. and Gütschow, M. and Döhner, H. and Walther, W. and Keller, U. and Bullinger, L. and Mertins, P. and Krönke, J.
Nature Communications 13 (1): 1009. 23 February 2022

Gene gun Her2/neu DNA vaccination: evaluation of vaccine efficacy in a syngeneic Her2/neu mouse tumor model.
Nguyen-Hoai, T. and Hohn, O. and Pezzutto, A. and Westermann, J.
Methods in Molecular Biology 2521 (3): 129-154. 23 June 2022

Effect of atmospheric aging on soot particle toxicity in lung cell models at the air-liquid interface: differential toxicological impacts of biogenic and anthropogenic secondary organic aerosols (SOAs).
Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Martens, P. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Pardo, M. and Gröger, T. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Rudich, Y. and Zimmermann, R.
Environmental Health Perspectives 130 (2): 27003. 3 February 2022

Lack of evidence for participation of TMEM150C in sensory mechanotransduction.
Ojeda-Alonso, J. and Bégay, V. and Garcia-Contreras, J.A. and Campos-Pérez, A.F. and Purfürst, B. and Lewin, G.R.
Journal of General Physiology 154 (12): e202213098. 5 December 2022

Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.
Ortiz-Zapater, E. and Bagley, D.C. and Hernandez, V.L. and Roberts, L.B. and Maguire, T.J.A. and Voss, F. and Mertins, P. and Kirchner, M. and Peset-Martin, I. and Woszczek, G. and Rosenblatt, J. and Gotthardt, M. and Santis, G. and Parsons, M.
Nature Communications 13 (1): 6407. 27 October 2022

Biosynthetic potential of the global ocean microbiome.
Paoli, L. and Ruscheweyh, H.J. and Forneris, C.C. and Hubrich, F. and Kautsar, S. and Bhushan, A. and Lotti, A. and Clayssen, Q. and Salazar, G. and Milanese, A. and Carlström, C.I. and Papadopoulou, C. and Gehrig, D. and Karasikov, M. and Mustafa, H. and Larralde, M. and Carroll, L.M. and Sánchez, P. and Zayed, A.A. and Cronin, D.R. and Acinas, S.G. and Bork, P. and Bowler, C. and Delmont, T.O. and Gasol, J.M. and Gossert, A.D. and Kahles, A. and Sullivan, M.B. and Wincker, P. and Zeller, G. and Robinson, S.L. and Piel, J. and Sunagawa, S.
Nature 607 (7917): 111-118. 7 July 2022

Microglia states and nomenclature: A field at its crossroads.
Paolicelli, R.C. and Sierra, A. and Stevens, B. and Tremblay, M.E. and Aguzzi, A. and Ajami, B. and Amit, I. and Audinat, E. and Bechmann, I. and Bennett, M. and Bennett, F. and Bessis, A. and Biber, K. and Bilbo, S. and Blurton-Jones, M. and Boddeke, E. and Brites, D. and Brône, B. and Brown, G.C. and Butovsky, O. and Carson, M.J. and Castellano, B. and Colonna, M. and Cowley, S.A. and Cunningham, C. and Davalos, D. and De Jager, P.L. and de Strooper, B. and Denes, A. and Eggen, B.J.L. and Eyo, U. and Galea, E. and Garel, S. and Ginhoux, F. and Glass, C.K. and Gokce, O. and Gomez-Nicola, D. and González, B. and Gordon, S. and Graeber, M.B. and Greenhalgh, A.D. and Gressens, P. and Greter, M. and Gutmann, D.H. and Haass, C. and Heneka, M.T. and Heppner, F.L. and Hong, S. and Hume, D.A. and Jung, S. and Kettenmann, H. and Kipnis, J. and Koyama, R. and Lemke, G. and Lynch, M. and Majewska, A. and Malcangio, M. and Malm, T. and Mancuso, R. and Masuda, T. and Matteoli, M. and McColl, B.W. and Miron, V.E. and Molofsky, A.V. and Monje, M. and Mracsko, E. and Nadjar, A. and Neher, J.J. and Neniskyte, U. and Neumann, H. and Noda, M. and Peng, B. and Peri, F. and Perry, V.H. and Popovich, P.G. and Pridans, C. and Priller, J. and Prinz, M. and Ragozzino, D. and Ransohoff, R.M. and Salter, M.W. and Schaefer, A. and Schafer, D.P. and Schwartz, M. and Simons, M. and Smith, C.J. and Streit, W.J. and Tay, T.L. and Tsai, L.H. and Verkhratsky, A. and von Bernhardi, R. and Wake, H. and Wittamer, V. and Wolf, S.A. and Wu, L.J. and Wyss-Coray, T.
Neuron 110 (21): 3458-3483. 2 November 2022

Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells.
Pardo, M. and Offer, S. and Hartner, E. and Di Bucchianico, S. and Bisig, C. and Bauer, S. and Pantzke, J. and Zimmermann, E.J. and Cao, X. and Binder, S. and Kuhn, E. and Huber, A. and Jeong, S. and Käfer, U. and Schneider, E. and Mesceriakovas, A. and Bendl, J. and Brejcha, R. and Buchholz, A. and Gat, D. and Hohaus, T. and Rastak, N. and Karg, E. and Jakobi, G. and Kalberer, M. and Kanashova, T. and Hu, Y. and Ogris, C. and Marsico, A. and Theis, F. and Shalit, T. and Gröger, T. and Rüger, C.P. and Oeder, S. and Orasche, J. and Paul, A. and Ziehm, T. and Zhang, Z.H. and Adam, T. and Sippula, O. and Sklorz, M. and Schnelle-Kreis, J. and Czech, H. and Kiendler-Scharr, A. and Zimmermann, R. and Rudich, Y.
Environment International 166 : 107366. August 2022

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K. and Leunig, A. and Kaiser, R. and Joppich, M. and Brambs, S. and Janjic, A. and Popp, O. and Nixdorf, D. and Fumagalli, V. and Schmidt, N. and Polewka, V. and Anjum, A. and Knottenberg, V. and Eivers, L. and Wange, L.E. and Gold, C. and Kirchner, M. and Muenchhoff, M. and Hellmuth, J.C. and Scherer, C. and Rubio-Acero, R. and Eser, T. and Deák, F. and Puchinger, K. and Kuhl, N. and Linder, A. and Saar, K. and Tomas, L. and Schulz, C. and Wieser, A. and Enard, W. and Kroidl, I. and Geldmacher, C. and von Bergwelt-Baildon, M. and Keppler, O.T. and Munschauer, M. and Iannacone, M. and Zimmer, R. and Mertins, P. and Hubner, N. and Hoelscher, M. and Massberg, S. and Stark, K. and Nicolai, L.
Nature Communications 13 (1): 1018. 23 February 2022

Neuroligins in neurodevelopmental conditions: how mouse models of de novo mutations can help us link synaptic function to social behavior.
Pohl, T. and Hörnberg, H.
Neuronal Signaling 6 (2): NS20210030. June 2022

Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics.
Pryszlak, A. and Wenzel, T. and Seitz, K.W. and Hildebrand, F. and Kartal, E. and Cosenza, M.R. and Benes, V. and Bork, P. and Merten, C.A.
Cell Reports Methods 2 (1): 100137. 24 January 2022

Targeting Wnt/β-catenin signaling by TET1/FOXO4 inhibits metastatic spreading and self-renewal of cancer stem cells in gastric cancer.
Qi, J. and Cui, D. and Wu, Q.N. and Zhao, Q. and Chen, Z.H. and Li, L. and Birchmeier, W. and Yu, Y. and Tao, R.
Cancers 14 (13): 3232. 30 June 2022

A novel gene controls a new structure: piggyBac transposable element-derived 1, unique to mammals, controls mammal-specific neuronal paraspeckles.
Raskó, T. and Pande, A. and Radscheit, K. and Zink, A. and Singh, M. and Sommer, C. and Wachtl, G. and Kolacsek, O. and Inak, G. and Szvetnik, A. and Petrakis, S. and Bunse, M. and Bansal, V. and Selbach, M. and Orbán, T.I. and Prigione, A. and Hurst, L.D. and Izsvák, Z.
Molecular Biology and Evolution 39 (10): msac175. October 2022

Functional and evolutionary significance of unknown genes from uncultivated taxa.
Rodríguez del Río, Á. and Giner-Lamia, J. and Cantalapiedra, C.P. and Botas, J. and Deng, Z. and Hernández-Plaza, A. and Paoli, L. and Schmidt, T.S.B. and Sunagawa, S. and Bork, P. and Coelho, L.P. and Huerta-Cepas, J.
bioRxiv : 10.1101/2022.01.26.477801. 27 January 2022

Development of an indole-amide-based photoswitchable cannabinoid receptor subtype 1 (CB(1)R) "Cis-On" agonist.
Rodríguez-Soacha, D.A. and Steinmüller, S.A.M. and Işbilir, A. and Fender, J. and Deventer, M.H. and Ramírez, Y.A. and Tutov, A. and Sotriffer, C. and Stove, C.P. and Lorenz, K. and Lohse, M.J. and Hislop, J.N. and Decker, M.
ACS Chemical Neuroscience 13 (16): 2410-2435. 17 August 2022

CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Rousselle, A. and Sonnemann, J. and Amann, K. and Mildner, A. and Lodka, D. and Kling, L. and Bieringer, M. and Schneider, U. and Leutz, A. and Enghard, P. and Kettritz, R. and Schreiber, A.
Annals of the Rheumatic Diseases 81 (8): 1162-1172. August 2022

Cultivation-independent genomes greatly expand taxonomic-profiling capabilities of mOTUs across various environments.
Ruscheweyh, H.J. and Milanese, A. and Paoli, L. and Karcher, N. and Clayssen, Q. and Keller, M.I. and Wirbel, J. and Bork, P. and Mende, D.R. and Zeller, G. and Sunagawa, S.
Microbiome 10 (1): 212. 5 December 2022

Enriched environment attenuates enhanced trait anxiety in association with normalization of aberrant neuro-inflammatory events.
Sah, A. and Rooney, S. and Kharitonova, M. and Sartori, S.B. and Wolf, S.A. and Singewald, N.
International Journal of Molecular Sciences 23 (21): 13052. 27 October 2022

High-fat-diet-evoked disruption of the rat dorsomedial hypothalamic clock can be prevented by restricted nighttime feeding.
Sanetra, A.M. and Acevedo-Ochoa, E. and Chrobok, L. and Jeczmien-Lazur, J.S. and Gawron, E. and Klich, J.D. and Pradel, K. and Lewandowski, M.H.
Nutrients 14 (23): 5034. 26 November 2022

Identification of environmental factors that promote intestinal inflammation.
Sanmarco, L.M. and Chao, C.C. and Wang, Y.C. and Kenison, J.E. and Li, Z. and Rone, J.M. and Rejano-Gordillo, C.M. and Polonio, C.M. and Gutierrez-Vazquez, C. and Piester, G. and Plasencia, A. and Li, L. and Giovannoni, F. and Lee, H.G. and Faust Akl, C. and Wheeler, M.A. and Mascanfroni, I. and Jaronen, M. and Alsuwailm, M. and Hewson, P. and Yeste, A. and Andersen, B.M. and Franks, D.G. and Huang, C.J. and Ekwudo, M. and Tjon, E.C. and Rothhammer, V. and Takenaka, M. and de Lima, K.A. and Linnerbauer, M. and Guo, L. and Covacu, R. and Queva, H. and Fonseca-Castro, P.H. and Bladi, M.A. and Cox, L.M. and Hodgetts, K.J. and Hahn, M.E. and Mildner, A. and Korzenik, J. and Hauser, R. and Snapper, S.B. and Quintana, F.J.
Nature 611 (7937): 801-809. 24 November 2022

Serum dihydrotestosterone is associated with adverse myocardial remodeling in patients with aortic valve stenosis before and after aortic valve replacement.
Schafstedde, M. and Nordmeyer, J. and Berger, F. and Knosalla, C. and Mertins, P. and Regitz-Zagrosek, V. and Kuehne, T. and Kraus, M. and Nordmeyer, S.
American Journal of Physiology Heart and Circulatory Physiology 323 (5): H949-H957. November 2022

Capillary gel electrophoresis (CGE) for quality control of plasmid DNA in gene therapy: quality control of 20 years stored GMP-grade plasmid DNA.
Schmeer, M. and Schleef, M. and Shankar, R. and Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521 (3): 317-328. 23 June 2022

Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker.
Schmid, F. and Dahlmann, M. and Röhrich, H. and Kobelt, D. and Hoffmann, J. and Burock, S. and Walther, W. and Stein, U.
British Journal of Cancer 127 (4): 675-685. 1 September 2022

Dissecting the intracellular pancreatic tumor microbiome at single-cell level.
Schmidt, T.S.B. and Bork, P.
Cancer Cell 40 (10): 1083-1085. 10 October 2022

Drivers and determinants of strain dynamics following fecal microbiota transplantation.
Schmidt, T.S.B. and Li, S.S. and Maistrenko, O.M. and Akanni, W. and Coelho, L.P. and Dolai, S. and Fullam, A. and Glazek, A.M. and Hercog, R. and Herrema, H. and Jung, F. and Kandels, S. and Orakov, A. and Thielemann, R. and von Stetten, M. and Van Rossum, T. and Benes, V. and Borody, T.J. and de Vos, W.M. and Ponsioen, C.Y. and Nieuwdorp, M. and Bork, P.
Nature Medicine 28 (9): 1902-1912. September 2022

Senescence and cancer - role and therapeutic opportunities.
Schmitt, C.A. and Wang, B. and Demaria, M.
Nature Reviews Clinical oncology 19 (10): 619–636. October 2022

Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours.
Schubert, N.A. and Chen, C.Y. and Rodríguez, A. and Koster, J. and Dowless, M. and Pfister, S.M. and Shields, D.J. and Stancato, L.F. and Vassal, G. and Caron, H.N. and van den Boogaard, M.L. and Henssen, A.G. and Molenaar, J.J.
European Journal of Cancer 170 : 196-208. July 2022

On the relation between input and output distributions of scRNA-seq experiments.
Schwabe, D. and Falcke, M.
Bioinformatics 38 (5): 1336-1343. 1 March 2022

Graph neural networks for learning molecular excitation spectra.
Singh, K. and Münchmeyer, J. and Weber, L. and Leser, U. and Bande, A.
Journal of Chemical Theory and Computation 18 (7): 4408-4417. 12 July 2022

Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors.
Specker, E. and Matthes, S. and Wesolowski, R. and Schütz, A. and Grohmann, M. and Alenina, N. and Pleimes, D. and Mallow, K. and Neuenschwander, M. and Gogolin, A. and Weise, M. and Pfeifer, J. and Ziebart, N. and Heinemann, U. and von Kries, J.P. and Nazaré, M. and Bader, M.
Journal of Medicinal Chemistry 65 (16): 11126-11149. 25 August 2022

Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas.
Staudacher, J.J. and Arnold, A. and Kühl, A.A. and Pötzsch, M. and Daum, S. and Winterfeld, M. and Berg, E. and Hummel, M. and Rau, B. and Stein, U. and Treese, C.
BMC Cancer 22 (1): 953. 5 September 2022

DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M. and Denker, S. and Schmitt, C.A.
Cancers 14 (6): 1453. 11 March 2022

Pan-claudin family interactome analysis reveals shared and specific interactions.
Suarez Artiles, L. and Breiderhoff, T. and Girardello, R. and Gonschior, H. and Rodius, S. and Lesur, A. and Reimer, U. and Ramberger, E. and Perez-Hernandez, D. and Müller, D. and Mertins, P. and Dittmar, G.
Cell Reports 41 (6): 111588. 8 November 2022

Skeletal muscle derived Musclin protects the heart during pathological overload.
Szaroszyk, M. and Kattih, B. and Martin-Garrido, A. and Trogisch, F.A. and Dittrich, G.M. and Grund, A. and Abouissa, A. and Derlin, K. and Meier, M. and Holler, T. and Korf-Klingebiel, M. and Völker, K. and Macedo, T.G. and Tortola, C.P. and Boschmann, M. and Huang, N. and Froese, N. and Zwadlo, C. and Malek Mohammadi, M. and Luo, X. and Wagner, M. and Cordero, J. and Geffers, R. and Batkai, S. and Thum, T. and Bork, N. and Nikolaev, V.O. and Müller, O.J. and Katus, H.A. and El-Armouche, A. and Kraft, T. and Springer, J. and Dobreva, G. and Wollert, K.C. and Fielitz, J. and von Haehling, S. and Kuhn, M. and Bauersachs, J. and Heineke, J.
Nature Communications 13 (1): 149. 10 January 2022

Genomic evolution and personalized therapy of an infantile fibrosarcoma harboring an NTRK oncogenic fusion.
Thorwarth, A. and Haase, K. and Röefzaad, C. and Pajtler, K.W. and Schramm, K. and Hauptmann, K. and Behnke, A. and Vokuhl, C. and Elgeti, T. and Gratopp, A. and Schulte, J.H. and Scheer, M. and Hernáiz Driever, P. and Nysom, K. and Eggert, A. and Henssen, A.G. and Deubzer, H.E.
JCO Precision Oncology 6 : e2100283. 25 May 2022

S100A4 is a strong negative prognostic marker and potential therapeutic target in adenocarcinoma of the stomach and esophagus.
Treese, C. and Hartl, K. and Pötzsch, M. and Dahlmann, M. and von Winterfeld, M. and Berg, E. and Hummel, M. and Timm, L. and Rau, B. and Walther, W. and Daum, S. and Kobelt, D. and Stein, U.
Cells 11 (6): 1056. 21 March 2022

Inhibition of MACC1-induced metastasis in esophageal and gastric adenocarcinomas.
Treese, C. and Werchan, J. and von Winterfeld, M. and Berg, E. and Hummel, M. and Timm, L. and Rau, B. and Daberkow, O. and Walther, W. and Daum, S. and Kobelt, D. and Stein, U.
Cancers 14 (7): 1773. 31 March 2022

TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation.
Tufan, A.B. and Lazarow, K. and Kolesnichenko, M. and Sporbert, A. and von Kries, J.P. and Scheidereit, C.
EMBO Journal 41 (21): e110372. 2 November 2022

Time-keeping and decision-making in living cells: Part II.
Tyson, J.J. and Csikasz-Nagy, A. and Gonze, D. and Kim, J.K. and Santos, S. and Wolf, J.
Interface Focus 12 (4): 20220024. 10 June 2022

Time-keeping and decision-making in living cells: Part I.
Tyson, J.J. and Csikasz-Nagy, A. and Gonze, D. and Kim, J.K. and Santos, S. and Wolf, J.
Interface Focus 12 (3): 20220011. 6 June 2022

Detection and validation of circular DNA fragments using nanopore sequencing.
Tüns, A.I. and Hartmann, T. and Magin, S. and Chamorro González, R. and Henssen, A.G. and Rahmann, S. and Schramm, A. and Köster, J.
Frontiers in Genetics 13 : 867018. 30 May 2022

Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses.
Ventura, P.M.O. and Gakovic, M. and Fischer, B.A. and Spinelli, L. and Rota, G. and Pathak, S. and Khameneh, H.J. and Zenobi, A. and Thomson, S. and Birchmeier, W. and Cantrell, D.A. and Guarda, G.
EMBO Reports 23 (11): e55399. 7 November 2022

Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20.
Vieira e Vieira, C.H. and Dauksaite, V. and Sporbert, A. and Gotthardt, M. and Selbach, M.
Molecular Cell 82 (11): 2069-2083. 2 June 2022

Elevated MACC1 expression in colorectal cancer is driven by chromosomal instability and is associated with molecular subtype and worse patient survival.
Vuaroqueaux, V. and Musch, A. and Kobelt, D. and Risch, T: and Herrmann, P. and Burock, S. and Peille, A.L. and Yaspo, M.L. and Fiebig, H.H. and Stein, U.
Cancers 14 (7): 1749. 1 April 2022

Disruptors of AKAP-dependent protein-protein interactions.
Walker-Gray, R. and Pallien, T. and Miller, D.C. and Oder, A. and Neuenschwander, M. and von Kries, J.P. and Diecke, S. and Klussmann, E.
Methods in Molecular Biology 2483 : 117-139. 2022

Gating choreography and mechanism of the human proton-activated chloride channel ASOR.
Wang, C. and Polovitskaya, M.M. and Delgado, B.D. and Jentsch, T.J. and Long, S.B.
Science Advances 8 (5): eabm3942. 2 February 2022

Chemical-protein relation extraction with ensembles of carefully tuned pretrained language models.
Weber, L. and Sänger, M. and Garda, S. and Barth, F. and Alt, C. and Leser, U.
Database 2022 : baac098. 18 November 2022

Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma.
Welters, C. and Lammoglia Cobo, M.F. and Stein, C.A. and Hsu, M.T. and Ben Hamza, A. and Penter, L. and Chen, X. and Buccitelli, C. and Popp, O. and Mertins, P. and Dietze, K. and Bullinger, L. and Moosmann, A. and Blanc, E. and Beule, D. and Gerbitz, A. and Strobel, J. and Hackstein, H. and Rahn, H.P. and Dornmair, K. and Blankenstein, T. and Hansmann, L.
Cancer Immunology Research 10 (11): 1407-1419. 1 November 2022

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C. and Doebele, C. and Zindel, A. and Lee, K.S. and Rieke, S.A. and Ceribelli, M. and Comoglio, F. and Phelan, J.D. and Wang, J.Q. and Pikman, Y. and Jahn, D. and Häupl, B. and Schneider, C. and Scheich, S. and Tosto, F.A. and Bohnenberger, H. and Stauder, P. and Schnütgen, F. and Slabicki, M. and Coulibaly, Z.A. and Wolf, S. and Bojarczuk, K. and Chapuy, B. and Brandts, C.H. and Stroebel, P. and Lewis, C.A. and Engelke, M. and Xu, X. and Kim, H. and Dang, T.H. and Schmitz, R. and Hodson, D.J. and Stegmaier, K. and Urlaub, H. and Serve, H. and Schmitt, C.A. and Kreuz, F. and Knittel, G. and Rabinowitz, J.D. and Reinhardt, H.C. and Vander Heiden, M.G. and Thomas, C. and Staudt, L.M. and Zenz, T. and Oellerich, T.
Blood 139 (4): 538-553. 27 January 2022

The transcription factor EB (TFEB) sensitizes the heart to chronic pressure overload.
Wundersitz, S. and Pablo Tortola, C. and Schmidt, S. and Oliveira Vidal, R. and Kny, M. and Hahn, A. and Zanders, L. and Katus, H.A. and Sauer, S. and Butter, C. and Luft, F.C. and Müller, O.J. and Fielitz, J.
International Journal of Molecular Sciences 23 (11): 5943. 25 May 2022

Radiofrequency electromagnetic fields cause non-temperature-induced physical and biological effects in cancer cells.
Wust, P. and Veltsista, P.D. and Oberacker, E. and Yavvari, P. and Walther, W. and Bengtsson, O. and Sterner-Kock, A. and Weinhart, M. and Heyd, F. and Grabowski, P. and Stintzing, S. and Heinrich, W. and Stein, U. and Ghadjar, P.
Cancers 14 (21): 5349. 30 October 2022

Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells.
Yang, M. and Yu, H. and Yu, X. and Liang, S. and Hu, Y. and Luo, Y. and Izsvák, Z. and Sun, C. and Wang, J.
Cell Stem Cell 29 (3): 400-418.e13. 3 March 2022

GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans.
Yao, Y. and Du Jiang, P. and Chao, B.N. and Cagdas, D. and Kubo, S. and Balasubramaniyam, A. and Zhang, Y. and Shadur, B. and NaserEddin, A. and Folio, L.R. and Schwarz, B. and Bohrnsen, E. and Zheng, L. and Lynberg, M. and Gottlieb, S. and Leney-Greene, M.A. and Park, A.Y. and Tezcan, I. and Akdogan, A. and Gocmen, R. and Onder, S. and Rosenberg, A. and Soilleux, E.J. and Johnson, E. and Jackson, P.K. and Demeter, J. and Chauvin, S.D. and Paul, F. and Selbach, M. and Bulut, H. and Clatworthy, M.R. and Tuong, Z.K. and Zhang, H. and Stewart, B.J. and Bosio, C.M. and Stepensky, P. and Clare, S. and Ganesan, S. and Pascall, J.C. and Daumke, O. and Butcher, G.W. and McMichael, A.J. and Simon, A.K. and Lenardo, M.J.
Journal of Experimental Medicine 219 (6): e20201405. 6 June 2022

Extrachromosomal DNA amplifications in cancer.
Yi, E. and Chamorro González, R. and Henssen, A.G. and Verhaak, R.G.W.
Nature Reviews Genetics 23 (12): 760-771. December 2022

Recapitulating early human development with 8C-like cells.
Yu, X. and Liang, S. and Chen, M. and Yu, H. and Li, R. and Qu, Y. and Kong, X. and Guo, R. and Zheng, R. and Izsvak, Z. and Sun, C. and Yang, M. and Wang, J.
Cell Reports 39 (12): 110994. 21 June 2022

Proton-gated anion transport governs macropinosome shrinkage.
Zeziulia, M. and Blin, S. and Schmitt, F.W. and Lehmann, M. and Jentsch, T.J.
Nature Cell Biology 24 (6): 885-895. June 2022

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation.
Zhou, D. and Borsa, M. and Puleston, D.J. and Zellner, S. and Capera, J. and Sanderson, S. and Schifferer, M. and Hester, S.S. and Ge, X. and Fischer, R. and Jostins, L. and Behrends, C. and Alsaleh, G. and Simon, A.K.
Nature Communications 13 (1): 5174. 2 September 2022

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins.
Zinnall, U. and Milek, M. and Minia, I. and Vieira-Vieira, C.H. and Müller, S. and Mastrobuoni, G. and Hazapis, O.G. and Del Giudice, S. and Schwefel, D. and Bley, N. and Voigt, F. and Chao, J.A. and Kempa, S. and Hüttelmaier, S. and Selbach, M. and Landthaler, M.
Nature Communications 13 (1): 2727. 18 May 2022

The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.
Zonderland, G. and Vanzo, R. and Amitash, S. and Martín-Doncel, E. and Coscia, F. and Mund, A. and Lerdrup, M. and Benada, J. and Boos, D. and Toledo, L.
Molecular Cell 82 (18): 3350-3365. 15 September 2022

Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction.
Zywitza, V. and Rusha, E. and Shaposhnikov, D. and Ruiz-Orera, J. and Telugu, N. and Rishko, V. and Hayashi, M. and Michel, G. and Wittler, L. and Stejskal, J. and Holtze, S. and Göritz, F. and Hermes, R. and Wang, J. and Izsvák, Z. and Colleoni, S. and Lazzari, G. and Galli, C. and Hildebrandt, T.B. and Hayashi, K. and Diecke, S. and Drukker, M.
Scientific Reports 12 (1): 3100. 8 March 2022

SMOG 2 and OpenSMOG: extending the limits of structure-based models.
de Oliveira, A.B. and Contessoto, V.G. and Hassan, A. and Byju, S. and Wang, A. and Wang, Y. and Dodero-Rojas, E. and Mohanty, U. and Noel, J.K. and Onuchic, J.N. and Whitford, P.C.
Protein Science 31 (1): 158-172. January 2022

The genomic and spatial mobility of extrachromosomal DNA and its implications for cancer therapy.
van Leen, E. and Brückner, L. and Henssen, A.G.
Nature Genetics 54 (2): 107-114. February 2022

2021

A role for STOML3 in olfactory sensory transduction.
Agostinelli, E. and Gonzalez-Velandia, K.Y. and Hernandez-Clavijo, A. and Maurya, D.K. and Xerxa, E. and Lewin, G.R. and Dibattista, M. and Menini, A. and Pifferi, S.
eNeuro 8 (2): ENEURO.0565-20.2021. 26 March 2021

From operating table to laboratory bench: the path toward metastasis research from the clinical setting.
Alberto Vilchez, M. and Rau, B.
Methods in Molecular Biology 2294 : 325-333. 2021

Identification of the gliogenic state of human neural stem cells to optimize in vitro astrocyte differentiation.
Alisch, M. and Kerkering, J. and Crowley, T. and Rosiewicz, K. and Paul, F. and Siffrin, V.
Journal of Neuroscience Methods 361 : 109284. 1 September 2021

Vasopressin-vermittelte Wasserrückresorption im Sammelrohr der Niere [Vasopressin-mediated water reabsorption in the renal collecting duct].
Baltzer, S. and Klussmann, E.
BIOspektrum 27 (2): 165-167. March 2021

Hearing and vocalizations in the naked mole-rat.
Barker, A.J. and Koch, U. and Lewin, G.R. and Pyott, S.J.
Advances in Experimental Medicine and Biology 1319 (1319): 157-195. 24 August 2021

Cultural transmission of vocal dialect in the naked mole-rat.
Barker, A.J. and Veviurko, G. and Bennett, N.C. and Hart, D.W. and Mograby, L. and Lewin, G.R.
Science 371 (6528): 503-507. 29 January 2021

Isolation, culture, and genetic engineering of mammalian primary pigment epithelial cells for non-viral gene therapy.
Bascuas, T. and Kropp, M. and Harmening, N. and Wong, B.M. and Johnen, S. and Izsvák, Z. and Thumann, G.
Journal of Visualized Experiments (168): e62145. 26 February 2021

Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes.
Bathe-Peters, M. and Gmach, P. and Boltz, H.H. and Einsiedel, J. and Gotthardt, M. and Hübner, H. and Gmeiner, P. and Lohse, M.J. and Annibale, P.
Proceedings of the National Academy of Sciences of the United States of America 118 (23): e2101119118. 8 June 2021

SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics.
Baytek, G. and Blume, A. and Gerceker Demirel, F. and Bulut, S. and Mertins, P. and Tursun, B.
bioRxiv : 2021.02.14.431134. 14 February 2021

Viewpoints on the first transatlantic GPCR symposium for early-career investigators.
Bender, B.J. and Bock, A. and Nesheva, D.N. and Perry-Hauser, N.A.
ACS Pharmacology & Translational Science 4 (5): 1705-1711. 8 October 2021

CARDIOKIN1: computational assessment of myocardial metabolic capability in healthy controls and patients with valve diseases.
Berndt, N. and Eckstein, J. and Wallach, I. and Nordmeyer, S. and Kelm, M. and Kirchner, M. and Goubergrits, L. and Schafstedde, M. and Hennemuth, A. and Kraus, M. and Grune, T. and Mertins, P. and Kuehne, T. and Holzhütter, H.G.
Circulation 144 (24): 1926-1939. 14 December 2021

Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient.
Bittner, A. and Radke, J. and Eurich, D. and Wiener, E. and Denker, S. and Anagnostopoulos, I. and Na, I.K. and Heppner, F.L. and Bullinger, L. and Schmitt, C.A.
Leukemia & Lymphoma 62 (8): 2026-2029. August 2021

Allosteric coupling and biased agonism in G protein-coupled receptors.
Bock, A. and Bermudez, M.
FEBS Journal 288 (8): 2513-2528. April 2021

Quantitative spectroscopy of single molecule interaction times.
Boltz, H.H. and Sirbu, A. and Stelzer, N. and Lohse, M.J. and Schütte, C. and Annibale, P.
Optics Letters 46 (7): 1538-1541. 1 April 2021

M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
Breitkreuz-Korff, O. and Tscheik, C. and Del Vecchio, G. and Dithmer, S. and Walther, W. and Orthmann, A. and Wolburg, H. and Haseloff, R.F. and Schröder, L. and Blasig, I.E. and Winkler, L.
Journal of Controlled Release 330 : 137-148. 10 August 2021

NF-κB determines Paneth versus goblet cell fate decision in the small intestine.
Brischetto, C. and Krieger, K. and Klotz, C. and Krahn, I. and Kunz, S. and Kolesnichenko, M. and Mucka, P. and Heuberger, J. and Scheidereit, C. and Schmidt-Ullrich, R.
Development 148 (21): dev199683. November 2021

Mitochondria in neurogenesis: implications for mitochondrial diseases.
Brunetti, D. and Dykstra, W. and Le, S. and Zink, A. and Prigione, A.
Stem Cells 39 (10): 1289-1297. October 2021

MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann, J. and Lorenz, C. and Borchmann, S. and Nishii, K. and Wegner, J. and Meder, L. and Ostendorp, J. and Ast, D.F. and Heimsoeth, A. and Nakasuka, T. and Hirabae, A. and Okawa, S. and Dammert, M.A. and Plenker, D. and Klein, S. and Lohneis, P. and Gu, J. and Godfrey, L.K. and Forster, J. and Trajkovic-Arsic, M. and Zillinger, T. and Haarmann, M. and Quaas, A. and Lennartz, S. and Schmiel, M. and D'Rozario, J. and Thomas, E.S. and Li, H. and Schmitt, C.A. and George, J. and Thomas, R.K. and von Karstedt, S. and Hartmann, G. and Büttner, R. and Ullrich, R.T. and Siveke, J.T. and Ohashi, K. and Schlee, M. and Sos, M.L.
Nature Communications 12 (1): 5505. 17 September 2021

Structural evidence of active site adaptability towards different sized substrates of aromatic amino acid aminotransferase from Psychrobacter sp. B6.
Bujacz, A. and Rum, J. and Rutkiewicz, M. and Pietrzyk-Brzezinska, A.J. and Bujacz, G.
Materials 14 (12): 3351. 2 June 2021

Inhibition of the NLRP3/IL-1β axis protects against sepsis-induced cardiomyopathy.
Busch, K. and Kny, M. and Huang, N. and Klassert, T.E. and Stock, M. and Hahn, A. and Graeger, S. and Todiras, M. and Schmidt, S. and Chamling, B. and Willenbrock, M. and Groß, S. and Biedenweg, D. and Heuser, A. and Scheidereit, C. and Butter, C. and Felix, S.B. and Otto, O. and Luft, F.C. and Slevogt, H. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 12 (6): 1653-1668. December 2021

Immune competence and spleen size scale with colony status in the naked mole-rat.
Bégay, V. and Cirovic, B. and Barker, A.J. and Klopfleisch, R. and Hart, D.W. and Bennett, N.C. and Lewin, G.R.
bioRxiv : 2021.08.15.456351. 15 August 2021

Cancer stem cells: advances in biology and clinical translation -- a Keystone Symposia report.
Cable, J. and Pei, D. and Reid, L.M. and Wang, X.W. and Bhatia, S. and Karras, P. and Melenhorst, J.J. and Grompe, M. and Lathia, J.D. and Song, E. and Kuo, C.J. and Zhang, N. and White, R.M. and Ma, S.K. and Ma, L. and Chin, Y.R. and Shen, M.M. and Ng, I.O.L. and Kaestner, K.H. and Zhou, L. and Sikandar, S. and Schmitt, C.A. and Guo, W. and Wong, C.C.L. and Ji, J. and Tang, D.G. and Dubrovska, A. and Yang, C. and Wiedemeyer, W.R. and Weissman, I.L.
Annals of the New York Academy of Sciences 1506 (1): 142–163. December 2021

Atypical antipsychotics and metabolic syndrome: from molecular mechanisms to clinical differences.
Carli, M. and Kolachalam, S. and Longoni, B. and Pintaudi, A. and Baldini, M. and Aringhieri, S. and Fasciani, I. and Annibale, P. and Maggio, R. and Scarselli, M.
Pharmaceuticals 14 (3): 238. March 2021

Enhanced properties of a benzimidazole benzylpyrazole lysine demethylase inhibitor: mechanism-of-action, binding site analysis, and activity in cellular models of prostate cancer.
Carter, D.M. and Specker, E. and Malecki, P.H. and Przygodda, J. and Dudaniec, K. and Weiss, M.S. and Heinemann, U. and Nazaré, M. and Gohlke, U.
Journal of Medicinal Chemistry 64 (19): 14266-14282. 14 October 2021

Functional characterization of ovine dorsal root ganglion neurons reveal peripheral sensitization after osteochondral defect.
Chakrabarti, S. and Ai, M. and Wong, K. and Newell, K. and Henson, F.M.D. and Smith, E.S.J.
eNeuro 8 (5): ENEURO.0237-21.2021. September 2021

FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development.
Chua, J.Y. and Ng, S.J. and Yagensky, O. and Wanker, E.E. and Chua, J.J.E.
eNeuro 8 (2): ENEURO.0193-20.2021. 26 March 2021

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G. and Bay, O. and Zinno, J. and Gutwein, M. and Gan, H.H. and Mayya, V.K. and Chung, G. and Chen, J.X. and Fahs, H. and Guan, Y. and Duchaine, T.F. and Selbach, M. and Piano, F. and Gunsalus, K.C.
eLife 10 : e60833. 3 August 2021

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules.
Cipriani, P.G. and Bay, O. and Zinno, J.P. and Gutwein, M. and Gan, H.H. and Mayya, V. and Chung, G. and Chen, J.X. and Fahs, H. and Guan, Y. and Duchaine, T. and Selbach, M. and Piano, F. and Gunsalus, K.
bioRxiv : 2021.06.17.448425. 17 June 2021

Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Dahlmann, M. and Gambara, G. and Brzezicha, B. and Popp, O. and Pachmayr, E. and Wedeken, L. and Pflaume, A. and Mokritzkij, M. and Gül-Klein, S. and Brandl, A. and Schweiger-Eisbacher, C. and Mertins, P. and Hoffmann, J. and Keilholz, U. and Walther, W. and Regenbrecht, C. and Rau, B. and Stein, U.
Molecular Cancer 20 (1): 129. 21 October 2021

A bioinformatic pipeline to identify biomarkers for metastasis formation from RNA sequencing data.
Dahlmann, M. and Stein, U.S.
Methods in Molecular Biology 2294 : 221-238. 2021

Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data.
Dimchev, G. and Amiri, B. and Fäßler, F. and Falcke, M. and Schur, F.K.M.
Journal of Structural Biology 213 (4): 107808. December 2021

Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data.
Dimchev, G. and Amiri, B. and Fäßler, F. and Falcke, M. and Schur, F.K.M.
bioRxiv : 2021.05.25.445599. 25 May 2021

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M. and Klinger, B. and Mari, T. and Toedling, J. and Blanc, E. and Messerschmidt, C. and Nadler-Holly, M. and Ziehm, M. and Sieber, A. and Hertwig, F. and Beule, D. and Eggert, A. and Schulte, J.H. and Selbach, M. and Blüthgen, N.
PLoS Computational Biology 17 (11): e1009515. 4 November 2021

Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.
Dorel, M. and Klinger, B. and Mari, T. and Toedling, J. and Blanc, E. and Messerschmidt, C. and Nadler-Holly, M. and Ziehm, M. and Sieber, A. and Hertwig, F. and Beule, D. and Eggert, A. and Schulte, J.H. and Selbach, M. and Blüthgen, N.
bioRxiv : 2021.06.14.448322. 14 June 2021

Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders.
Duncan, A.R. and Polovitskaya, M.M. and Gaitán-Peñas, H. and Bertelli, S. and VanNoy, G.E. and Grant, P.E. and O'Donnell-Luria, A. and Valivullah, Z. and Lovgren, A.K. and England, E.M. and Agolini, E. and Madden, J.A. and Schmitz-Abe, K. and Kritzer, A. and Hawley, P. and Novelli, A. and Alfieri, P. and Colafati, G.S. and Wieczorek, D. and Platzer, K. and Luppe, J. and Koch-Hogrebe, M. and Abou Jamra, R. and Neira-Fresneda, J. and Lehman, A. and Boerkoel, C.F. and Seath, K. and Clarke, L. and van Ierland, Y. and Argilli, E. and Sherr, E.H. and Maiorana, A. and Diel, T. and Hempel, M. and Bierhals, T. and Estévez, R. and Jentsch, T.J. and Pusch, M. and Agrawal, P.B.
American Journal of Human Genetics 108 (8): 1450-1465. 5 August 2021

Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism.
Ehlers, L. and Kuppe, A. and Damerau, A. and Wilantri, S. and Kirchner, M. and Mertins, P. and Strehl, C. and Buttgereit, F. and Gaber, T.
FASEB Journal 35 (7): e21684. July 2021

Thymoquinone: a tie-breaker in SARS-CoV2-infected cancer patients?
Elgohary, S. and Elkhodiry, A.A. and Amin, N.S. and Stein, U. and El Tayebi, H.M.
Cells 10 (2): 302. 2 February 2021

Imlifidase as novel treatment strategy in anti-neutrophil cytoplasmic antibody–induced pulmonary-renal syndrome.
Enghard, P. and Zickler, D. and Sonnemann, J. and Schneider, W. and Lurje, G. and Elezkurtaj, S. and Eckardt, K.U. and Schreiber, A.
Kidney International 100 (6): 1344-1345. December 2021

Reactive astrocyte nomenclature, definitions, and future directions.
Escartin, C. and Galea, E. and Lakatos, A. and O'Callaghan, J.P. and Petzold, G.C. and Serrano-Pozo, A. and Steinhäuser, C. and Volterra, A. and Carmignoto, G. and Agarwal, A. and Allen, N.J. and Araque, A. and Barbeito, L. and Barzilai, A. and Bergles, D.E. and Bonvento, G. and Butt, A.M. and Chen, W.T. and Cohen-Salmon, M. and Cunningham, C. and Deneen, B. and De Strooper, B. and Díaz-Castro, B. and Farina, C. and Freeman, M. and Gallo, V. and Goldman, J.E. and Goldman, S.A. and Götz, M. and Gutiérrez, A. and Haydon, P.G. and Heiland, D.H. and Hol, E.M. and Holt, M.G. and Iino, M. and Kastanenka, K.V. and Kettenmann, H. and Khakh, B.S. and Koizumi, S. and Lee, C.J. and Liddelow, S.A. and MacVicar, B.A. and Magistretti, P. and Messing, A. and Mishra, A. and Molofsky, A.V. and Murai, K.K. and Norris, C.M. and Okada, S. and Oliet, S.H.R. and Oliveira, J.F. and Panatier, A. and Parpura, V. and Pekna, M. and Pekny, M. and Pellerin, L. and Perea, G. and Pérez-Nievas, B.G. and Pfrieger, F.W. and Poskanzer, K.E. and Quintana, F.J. and Ransohoff, R.M. and Riquelme-Perez, M. and Robel, S. and Rose, C.R. and Rothstein, J.D. and Rouach, N. and Rowitch, D.H. and Semyanov, A. and Sirko, S. and Sontheimer, H. and Swanson, R.A. and Vitorica, J. and Wanner, I.B. and Wood, L.B. and Wu, J. and Zheng, B. and Zimmer, E.R. and Zorec, R. and Sofroniew, M.V. and Verkhratsky, A.
Nature Neuroscience 24 (3): 312-325. March 2021

Stochastic reaction-diffusion modeling of calcium dynamics in 3D-dendritic spines of purkinje cells.
Friedhoff, V.N. and Antunes, G. and Falcke, M. and Simões de Souza, F.M.
Biophysical Journal 120 (11): 2112-2123. 1 June 2021

Models of stochastic Ca(2+) spiking : established approaches and inspirations from models of neuronal spikes.
Friedhoff, V.N. and Ramlow, L. and Lindner, B. and Falcke, M.
European Physical Journal Special Topics 230 (16-17): 2911-2928. October 2021

Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories.
Friedrich, C. and Schallenberg, S. and Kirchner, M. and Ziehm, M. and Niquet, S. and Haji, M. and Beier, C. and Neudecker, J. and Klauschen, F. and Mertins, P.
Nature Communications 12 (1): 3576. 11 June 2021

Use of cement suspension as an alternative matrix material for textile-reinforced concrete.
Fürst, R. and Fürst, E. and Vlach, T. and Řepka, J. and Pokorný, M. and Mózer, V.
Materials 14 (9): 2127. 1 May 2021

Place fields of single spikes in hippocampus involve Kcnq3 channel-dependent entrainment of complex spike bursts.
Gao, X. and Bender, F. and Soh, H. and Chen, C. and Altafi, M. and Schütze, S. and Heidenreich, M. and Gorbati, M. and Corbu, M.A. and Carus-Cadavieco, M. and Korotkova, T. and Tzingounis, A.V. and Jentsch, T.J. and Ponomarenko, A.
Nature Communications 12 (1): 4801. 10 August 2021

PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Garg, A. and Roske, Y. and Yamada, S. and Uehata, T. and Takeuchi, O. and Heinemann, U.
Nucleic Acids Research 49 (9): 5369-5381. 21 May 2021

Recurrent frameshift neoantigen vaccine elicits protective immunity with reduced tumor burden and improved overall survival in a Lynch syndrome mouse model.
Gebert, J. and Gelincik, O. and Oezcan-Wahlbrink, M. and Marshall, J.D. and Hernandez-Sanchez, A. and Urban, K. and Long, M. and Cortes, E. and Tosti, E. and Katzenmaier, E.M. and Song, Y. and Elsaadi, A. and Deng, N. and Vilar, E. and Fuchs, V. and Nelius, N. and Yuan, Y.P. and Ahadova, A. and Sei, S. and Shoemaker, R.H. and Umar, A. and Wei, L. and Liu, S. and Bork, P. and Edelmann, W. and von Knebel Doeberitz, M. and Lipkin, S.M. and Kloor, M.
Gastroenterology 161 (4): 288-1302.e13. October 2021

Identifying cell-type-specific metabolic signatures using transcriptome and proteome analyses.
Gebert, N. and Rahman, S. and Lewis, C.A. and Ori, A. and Cheng, C.W.
Current Protocols 1 (9): e245. 28 September 2021

Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin.
Gillissen, B. and Richter, A. and Essmann, F. and Kemmner, W.
BMC Cancer 21 (1): 971. 30 August 2021

Editorial: Monocyte heterogeneity and function.
Ginhoux, F. and Mildner, A. and Gautier, E.L. and Schlitzer, A. and Jakubzick, C. and Varol, C. and Bain, C. and Guermonprez, P.
Frontiers in Immunology 11 : 626725. 7 January 2021

Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O. and Zincke, F. and Eckert, A. and Kobelt, D. and Preissner, S. and Liebeskind, J.M. and Gunkel, N. and Putzker, K. and Lewis, J. and Preissner, S. and Kortüm, B. and Walther, W. and Mura, C. and Bourne, P.E. and Stein, U. and Preissner, R.
medRxiv : 2021.07.20.21260891. 22 July 2021

MLL1 is required for maintenance of intestinal stem cells.
Goveas, N. and Waskow, C. and Arndt, K. and Heuberger, J. and Zhang, Q. and Alexopoulou, D. and Dahl, A. and Birchmeier, W. and Anastassiadis, K. and Stewart, A.F. and Kranz, A.
PLoS Genetics 17 (12): e1009250. 3 December 2021

The need for sustainable leadership in academia : a survey of academics in Germany shows a lack of and a great demand for training in leadership skills.
Haage, V. and Voss, L. and Nguyen, D. and Eggert, F.
EMBO Reports 22 (12): e53592. 6 December 2021

Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice.
Hammer, K.P. and Mustroph, J. and Stauber, T. and Birchmeier, W. and Wagner, S. and Maier, L.S.
PLoS ONE 16 (6): e0252649. 4 June 2021

Timed global reorganization of protein synthesis during neocortex neurogenesis at codon resolution.
Harnett, D. and Ambrozkiewicz, M.C. and Zinnall, U. and Borisova, E. and Rusanova, A. and Dannenberg, R. and Imami, K. and Münster-Wandowski, A. and Fauler, B. and Mielke, T. and Selbach, M. and Landthaler, M. and Spahn, C.M.T. and Tarabykin, V. and Ohler, U. and Kraushar, M.L.
bioRxiv : 2021.06.23.449626. 24 June 2021

Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb, S.A. and Sieverling, L. and Nadler-Holly, M. and Ziehm, M. and Toprak, U.H. and Herrmann, C. and Ishaque, N. and Okonechnikov, K. and Gartlgruber, M. and Park, Y.G. and Wecht, E.M. and Savelyeva, L. and Henrich, K.O. and Rosswog, C. and Fischer, M. and Hero, B. and Jones, D.T.W. and Pfaff, E. and Witt, O. and Pfister, S.M. and Volckmann, Ri. and Koster, J. and Kiesel, K. and Rippe, K. and Taschner-Mandl, S. and Ambros, P. and Brors, B. and Selbach, M. and Feuerbach, L. and Westermann, F.
Nature Communications 12 (1): 1269. 24 February 2021

Insulin-like growth factor binding protein-2 (IGFBP2) is a key molecule in the MACC1-mediated platelet communication and metastasis of colorectal cancer cells.
Haschemi, R. and Kobelt, D. and Steinwarz, E. and Schlesinger, M. and Stein, U. and Bendas, G.
International Journal of Molecular Sciences 22 (22): 12195. 11 November 2021

Cold-shock domains - abundance, structure, properties, and nucleic-acid binding.
Heinemann, U. and Roske, Y.
Cancers 13 (2): 190. 7 January 2021

Dual-color fluorescence cross-correlation spectroscopy to study protein-protein interaction and protein dynamics in live cells.
Hemmen, K. and Choudhury, S. and Friedrich, M. and Balkenhol, J. and Knote, F. and Lohse, M. and Heinze, K.G.
bioRxiv : 2021.09.10.459760v1. 12 September 2021

Dual-color fluorescence cross-correlation spectroscopy to study protein-protein interaction and protein dynamics in live cells.
Hemmen, K. and Choudhury, S. and Friedrich, M. and Balkenhol, J. and Knote, F. and Lohse, M.J. and Heinze, K.G.
Journal of Visualized Experiments 178 : e62954. 11 December 2021

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
Heuberger, J. and Grinat, J. and Kosel, F. and Liu, L. and Kunz, S. and Vidal, R.O. and Keil, M. and Haybaeck, J. and Robine, S. and Louvard, D. and Regenbrecht, C. and Sporbert, A. and Sauer, S. and von Eyss, B. and Sigal, M. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 118 (22): e2019699118. 1 June 2021

Dispersal strategies shape persistence and evolution of human gut bacteria.
Hildebrand, F. and Gossmann, T.I. and Frioux, C. and Özkurt, E. and Myers, P.N. and Ferretti, P. and Kuhn, M. and Bahram, M. and Nielsen, H.B. and Bork, P.
Cell Host & Microbe 29 (7): 1167-1176. 14 June 2021

Glial cell line‐derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia‐mediated glioma progression.
Huang, Y. and Zhang, B. and Haneke, H. and Haage, V. and Lubas, M. and Yuan, Y. and Xia, P. and Motta, E. and Nanvuma, C. and Dzaye, O. and Hu, F. and Kettenmann, H.
Journal of Neuroscience Research 99 (4): 1048-1063. April 2021

ecDNA hubs drive cooperative intermolecular oncogene expression.
Hung, K.L. and Yost, K.E. and Xie, L. and Shi, Q. and Helmsauer, K. and Luebeck, J. and Schöpflin, R. and Lange, J.T. and Chamorro González, R. and Weiser, N.E. and Chen, C. and Valieva, M.E. and Wong, I.T.L. and Wu, S. and Dehkordi, S.R. and Duffy, C.V. and Kraft, K. and Tang, J. and Belk, J.A. and Rose, J.C. and Corces, M.R. and Granja, J.M. and Li, R. and Rajkumar, U. and Friedlein, J. and Bagchi, A. and Satpathy, A.T. and Tjian, R. and Mundlos, S. and Bafna, V. and Henssen, A.G. and Mischel, P.S. and Liu, Z. and Chang, H.Y.
Nature 600 (7890): 731-736. 23 December 2021

MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari, F. and Dahlmann, M. and Sporbert, A. and Ciolli Mattioli, C. and Mari, T. and Scholz, F. and Timm, L. and Twamley, S. and Migotti, R. and Walther, W. and Dittmar, G. and Rehm, A. and Stein, U.
Cellular and Molecular Life Sciences 78 (7): 3525-3542. April 2021

Bioenergetic profiling of human pluripotent stem cells.
Inak, G. and Henke, M.T. and Prigione, A.
Methods in Molecular Biology 2277 : 391-403. 2021

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome.
Inak, G. and Rybak-Wolf, A. and Lisowski, P. and Pentimalli, T.M. and Jüttner, R. and Glažar, P. and Uppal, K. and Bottani, E. and Brunetti, D. and Secker, C. and Zink, A. and Meierhofer, D. and Henke, M.T. and Dey, M. and Ciptasari, U. and Mlody, B. and Hahn, T. and Berruezo-Llacuna, M. and Karaiskos, N. and Di Virgilio, M. and Mayr, J.A. and Wortmann, S.B. and Priller, J. and Gotthardt, M. and Jones, D.P. and Mayatepek, E. and Stenzel, W. and Diecke, S. and Kühn, R. and Wanker, E.E. and Rajewsky, N. and Schuelke, M. and Prigione, A.
Nature Communications 12 (1): 1929. 26 March 2021

Pantoea stewartii WceF is a glycan biofilm modifying enzyme with a bacteriophage tailspike-like fold.
Irmscher, T. and Roske, Y. and Gayk, I. and Dunsing, V. and Chiantia, S. and Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 296 : 100286. 2021

Determination of G-protein-coupled receptor oligomerization by molecular brightness analyses in single cells.
Işbilir, A. and Serfling, R. and Möller, J. and Thomas, R. and De Faveri, C. and Zabel, U. and Scarselli, M. and Beck-Sickinger, A.G. and Bock, A. and Coin, I. and Lohse, M.J. and Annibale, P.
Nature Protocols 16 (3): 1419-1451. March 2021

Electroporation-based genetic modification of primary human pigment epithelial cells using the Sleeping Beauty transposon system.
Johnen, S. and Harmening, N. and Marie, C. and Scherman, D. and Izsvák, Z. and Ivics, Z. and Walter, P. and Thumann, G.
Journal of Visualized Experiments (168): e61987. February 2021

Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.
Kaiser, R. and Leunig, A. and Pekayvaz, K. and Popp, O. and Joppich, M. and Polewka, V. and Escaig, R. and Anjum, A. and Hoffknecht, M.L. and Gold, C. and Brambs, S. and Engel, A. and Stockhausen, S. and Knottenberg, V. and Titova, A. and Haji, M. and Scherer, C. and Muenchhoff, M. and Hellmuth, J.C. and Saar, K. and Schubert, B. and Hilgendorff, A. and Schulz, C. and Kääb, S. and Zimmer, R. and Hübner, N. and Massberg, S. and Mertins, P. and Nicolai, L. and Stark, K.
JCI Insight 6 (18): e150862. 22 September 2021

Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.
Kamdem, N. and Roske, Y. and Kovalskyy, D. and Platonov, M.O. and Balinskyi, O. and Kreuchwig, A. and Saupe, J. and Fang, L. and Diehl, A. and Schmieder, P. and Krause, G. and Rademann, J. and Heinemann, U. and Birchmeier, W. and Oschkinat, H.
Magnetic Resonance 2 (1): 355-374. 2 June 2021

Reconstitution of β-adrenergic regulation of Ca(V)1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.
Katz, M. and Subramaniam, S. and Chomsky-Hecht, O. and Tsemakhovich, V. and Flockerzi, V. and Klussmann, E. and Hirsch, J.A. and Weiss, S. and Dascal, N.
Proceedings of the National Academy of Sciences of the United States of America 118 (21): e2100021118. 17 May 2021

Subclone eradication analysis identifies targets for enhanced cancer therapy and reveals L1 retrotransposition as a dynamic source of cancer heterogeneity.
Ketola, K. and Kaljunen, H. and Taavitsainen, S. and Kaarijärvi, R. and Järvelä, E. and Rodriguez Martin, B. and Haase, K. and Woodcock, D.J. and Tubio, J. and Wedge, D.C. and Nykter, M. and Bova, G.S.
Cancer Research 81 (19): 4901-4909. October 2021

Glial cells: neuroglia.
Kettenmann, H. and Verkhratsky, A.
In: Neuroscience in the 21st century : from basic to clinical. Springer, New York, NY, 1-36. ISBN 978-1-4614-6434-1 12 April 2021

UNC93B1 is widely expressed in the murine CNS and is required for neuroinflammation and neuronal injury induced by microRNA let-7b.
Klammer, M.G. and Dzaye, O. and Wallach, T. and Krüger, C. and Gaessler, D. and Buonfiglioli, A. and Derkow, K. and Kettenmann, H. and Brinkmann, M.M. and Lehnardt, S.
Frontiers in Immunology 12 : 715774. September 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Klionsky, D.J. and Abdel-Aziz, A.K. and Abdelfatah, S. and Abdellatif, M. and Abdoli, A. and Abel, S. and Abeliovich, H. and Abildgaard, M.H. and Abudu, Y.P. and Acevedo-Arozena, A. and Adamopoulos, I.E. and Adeli, K. and Adolph, T.E. and Adornetto, A. and Aflaki, E. and Agam, G. and Agarwal, A. and Aggarwal, B.B. and Agnello, M. and Agostinis, P. and Agrewala, J.N. and Agrotis, A. and Aguilar, P.V. and Ahmad, S.T. and Ahmed, Z.M. and Ahumada-Castro, U. and Aits, S. and Aizawa, S. and Akkoc, Y. and Akoumianaki, T. and Akpinar, H.A. and Al-Abd, A.M. and Al-Akra, L. and Al-Gharaibeh, A. and Alaoui-Jamali, M.A. and Alberti, S. and Alcocer-Gómez, E. and Alessandri, C. and Ali, M. and Alim Al-Bari, M.A. and Aliwaini, S. and Alizadeh, J. and Almacellas, E. and Almasan, A. and Alonso, A. and Alonso, G.D. and Altan-Bonnet, N. and Altieri, D.C. and Álvarez, E.M.C. and Alves, S. and Alves da Costa, C. and Alzaharna, M.M. and Amadio, M. and Amantini, C. and Amaral, C. and Ambrosio, S. and Amer, A.O. and Ammanathan, V. and An, Z. and Andersen, S.U. and Andrabi, S.A. and Andrade-Silva, M. and Andres, A.M. and Angelini, S. and Ann, D. and Anozie, U.C. and Ansari, M.Y. and Antas, P. and Antebi, A. and Antón, Z. and Anwar, T. and Apetoh, L. and Apostolova, N. and Araki, T. and Araki, Y. and Arasaki, K. and Araújo, W.L. and Araya, J. and Arden, C. and Arévalo, M.A. and Arguelles, S. and Arias, E. and Arikkath, J. and Arimoto, H. and Ariosa, A.R. and Armstrong-James, D. and Arnauné-Pelloquin, L. and Aroca, A. and Arroyo, D.S. and Arsov, I. and Artero, R. and Asaro, D.M.L. and Aschner, M. and Ashrafizadeh, M. and Ashur-Fabian, O. and Atanasov, A.G. and Au, A.K. and Auberger, P. and Auner, H.W. and Aurelian, L. and Autelli, R. and Avagliano, L. and Ávalos, Y. and Aveic, S. and Aveleira, C.A. and Avin-Wittenberg, T. and Aydin, Y. and Ayton, S. and Ayyadevara, S. and Azzopardi, M. and Baba, M.u and Backer, J.M. and Backues, S.K. and Bae, D.H. and Bae, O.N. and Bae, S.H. and Baehrecke, E.H. and Baek, A. and Baek, S.H. and Baek, S.H. and Bagetta, G. and Bagniewska-Zadworna, A. and Bai, H. and Bai, J. and Bai, X. and Bai, Y. and Bairagi, N. and Baksi, S. and Balbi, T. and Baldari, C.T. and Balduini, W. and Ballabio, A. and Ballester, M. and Balazadeh, S. and Balzan, R. and Bandopadhyay, R. and Banerjee, S. and Banerjee, S. and Bánréti, A. and Bao, Y. and Baptista, M.S. and Baracca, A. and Barbati, C. and Bargiela, A. and Barilà, D. and Barlow, P.G. and Barmada, S.J. and Barreiro, E. and Barreto, G.E. and Bartek, J. and Bartel, B. and Bartolome, A. and Barve, G.R. and Basagoudanavar, S.H. and Bassham, D.C. and Bast, R.C. and Basu, A. and Batoko, H. and Batten, I. and Baulieu, E.E. and Baumgarner, B.L. and Bayry, J. and Beale, R. and Beau, I. and Beaumatin, F. and Bechara, L.R.G. and Beck, G.R. and Beers, M.F. and Begun, J. and Behrends, C. and Behrens, G.M.N. and Bei, R. and Bejarano, E. and Bel, S. and Behl, C. and Belaid, A. and Belgareh-Touzé, N. and Bellarosa, C. and Belleudi, F. and Belló Pérez, M. and Bello-Morales, R. and Beltran, J.S.O. and Beltran, S. and Benbrook, D.M. and Bendorius, M. and Benitez, B.A. and Benito-Cuesta, I. and Bensalem, J. and Berchtold, M.W. and Berezowska, S. and Bergamaschi, D. and Bergami, M. and Bergmann, A. and Berliocchi, L. and Berlioz-Torrent, C. and Bernard, A. and Berthoux, L. and Besirli, C.G. and Besteiro, S. and Betin, V.M. and Beyaert, R. and Bezbradica, J.S. and Bhaskar, K. and Bhatia-Kissova, I. and Bhattacharya, R. and Bhattacharya, S. and Bhattacharyya, S. and Bhuiyan, M.S. and Bhutia, S.K. and Bi, L. and Bi, X. and Biden, T.J. and Bijian, K. and Billes, V.A. and Binart, N. and Bincoletto, C. and Birgisdottir, A.B. and Bjorkoy, G. and Blanco, G. and Blas-Garcia, A. and Blasiak, J. and Blomgran, R. and Blomgren, K. and Blum, J.S. and Boada-Romero, E. and Boban, M. and Boesze-Battaglia, K. and Boeuf, P. and Boland, B. and Bomont, P. and Bonaldo, P. and Bonam, S.R. and Bonfili, L. and Bonifacino, J.S. and Boone, B.A. and Bootman, M.D. and Bordi, M. and Borner, C. and Bornhauser, B.C. and Borthakur, G. and Bosch, J. and Bose, S. and Botana, L.M. and Botas, J. and Boulanger, C.M. and Boulton, M.E. and Bourdenx, M. and Bourgeois, B. and Bourke, N.M. and Bousquet, G. and Boya, P. and Bozhkov, P.V. and Bozi, L.H.M. and Bozkurt, T.O. and Brackney, D.E. and Brandts, C.H. and Braun, R.J. and Braus, G.H. and Bravo-Sagua, R. and Bravo-San Pedro, J.M. and Brest, P. and Bringer, M.A. and Briones-Herrera, A. and Broaddus, V.C. and Brodersen, P. and Brodsky, J.L. and Brody, S.L. and Bronson, P.G. and Bronstein, J.M. and Brown, C.N. and Brown, R.E. and Brum, P.C. and Brumell, J.H. and Brunetti-Pierri, N. and Bruno, D. and Bryson-Richardson, R.J. and Bucci, C. and Buchrieser, C. and Bueno, M. and Buitrago-Molina, L.E. and Buraschi, S. and Buch, S. and Buchan, J.R. and Buckingham, E.M. and Budak, H. and Budini, M. and Bultynck, G. and Burada, F. and Burgoyne, J.R. and Burón, M.I. and Bustos, V. and Büttner, S. and Butturini, E. and Byrd, A. and Cabas, I. and Cabrera-Benitez, S. and Cadwell, K. and Cai, J. and Cai, L. and Cai, Q. and Cairó, M. and Calbet, J.A. and Caldwell, G.A. and Caldwell, K.A. and Call, J.A. and Calvani, R. and Calvo, A.C. and Calvo-Rubio Barrera, M. and Camara, N.O. and Camonis, J.H. and Camougrand, N. and Campanella, M. and Campbell, E.M. and Campbell-Valois, F.X. and Campello, S. and Campesi, I. and Campos, J.C. and Camuzard, O. and Cancino, J. and Candido de Almeida, D. and Canesi, L. and Caniggia, I. and Canonico, B. and Cantí, C. and Cao, B. and Caraglia, M. and Caramés, B. and Carchman, E.H. and Cardenal-Muñoz, E. and Cardenas, C. and Cardenas, L. and Cardoso, S.M. and Carew, J.S. and Carle, G.F. and Carleton, G. and Carloni, S. and Carmona-Gutierrez, D. and Carneiro, L.A. and Carnevali, O. and Carosi, J.M. and Carra, S. and Carrier, A. and Carrier, L. and Carroll, B. and Carter, A.B. and Carvalho, A.N. and Casanova, M. and Casas, C. and Casas, J. and Cassioli, C. and Castillo, E.F. and Castillo, K. and Castillo-Lluva, S. and Castoldi, F. and Castori, M. and Castro, A.F. and Castro-Caldas, M. and Castro-Hernandez, J. and Castro-Obregon, S. and Catz, S.D. and Cavadas, C. and Cavaliere, F. and Cavallini, G. and Cavinato, M. and Cayuela, M.L. and Cebollada Rica, P. and Cecarini, V. and Cecconi, F. and Cechowska-Pasko, M. and Cenci, S. and Ceperuelo-Mallafré, V. and Cerqueira, J.J. and Cerutti, J.M. and Cervia, D. and Cetintas, V.B. and Cetrullo, S. and Chae, H.J. and Chagin, A.S. and Chai, C.Y. and Chakrabarti, G. and Chakrabarti, O. and Chakraborty, T. and Chakraborty, T. and Chami, M. and Chamilos, G. and Chan, D.W. and Chan, E.Y.W. and Chan, E.D. and Chan, H.Y.E. and Chan, H.H. and Chan, H. and Chan, M.T.V. and Chan, Y.S. and Chandra, P.K. and Chang, C.P. and Chang, C. and Chang, H.C. and Chang, K. and Chao, J. and Chapman, T. and Charlet-Berguerand, N. and Chatterjee, S. and Chaube, S.K. and Chaudhary, A. and Chauhan, S. and Chaum, E. and Checler, F. and Cheetham, M.E. and Chen, C.S. and Chen, G.C. and Chen, J.F. and Chen, L.L. and Chen, L. and Chen, L. and Chen, M. and Chen, M.K. and Chen, N. and Chen, Q. and Chen, R.H. and Chen, S. and Chen, W. and Chen, W. and Chen, X.M. and Chen, X.W. and Chen, X. and Chen, Y. and Chen, Y.G. and Chen, Y. and Chen, Y. and Chen, Y.J. and Chen, Y.Q. and Chen, Z.S. and Chen, Z. and Chen, Z.H. and Chen, Z.J. and Chen, Z. and Cheng, H. and Cheng, J. and Cheng, S.Y. and Cheng, W. and Cheng, X. and Cheng, X.T. and Cheng, Y. and Cheng, Z. and Chen, Z. and Cheong, H. and Cheong, J.K. and Chernyak, B.V. and Cherry, S. and Cheung, C.F.R. and Cheung, C.H.A. and Cheung, K.H. and Chevet, E. and Chi, R.J. and Chiang, A.K.S. and Chiaradonna, F. and Chiarelli, R. and Chiariello, M. and Chica, N. and Chiocca, S. and Chiong, M. and Chiou, S.H. and Chiramel, A.I. and Chiurchiù, V. and Cho, D.H. and Choe, S.K. and Choi, A.M.K. and Choi, M.E. and Choudhury, K.R. and Chow, N.S. and Chu, C.T. and Chua, J.P. and Chua, J.J.E. and Chung, H. and Chung, K.P. and Chung, S. and Chung, S.H. and Chung, Y.L. and Cianfanelli, V. and Ciechomska, I.A. and Cifuentes, M. and Cinque, L. and Cirak, S. and Cirone, M. and Clague, M.J. and Clarke, R. and Clementi, E. and Coccia, E.M. and Codogno, P. and Cohen, E. and Cohen, M.M and Colasanti, T. and Colasuonno, F. and Colbert, R.A. and Colell, A. and Čolić, M. and Coll, N.S. and Collins, M.O. and Colombo, M.I. and Colón-Ramos, D.A. and Combaret, L. and Comincini, S. and Cominetti, M.R. and Consiglio, A. and Conte, A. and Conti, F. and Contu, V.R. and Cookson, M.R. and Coombs, K.M. and Coppens, I. and Corasaniti, M.T. and Corkery, D.P. and Cordes, N. and Cortese, K. and Costa, M.D.C. and Costantino, S. and Costelli, P. and Coto-Montes, A. and Crack, P.J. and Crespo, J.L. and Criollo, A. and Crippa, V. and Cristofani, R. and Csizmadia, T. and Cuadrado, A. and Cui, B. and Cui, J. and Cui, Y. and Cui, Y. and Culetto, E. and Cumino, A.C. and Cybulsky, A.V. and Czaja, M.J. and Czuczwar, S.J. and D'Adamo, S. and D'Amelio, M. and D'Arcangelo, D. and D'Lugos, A.C. and D'Orazi, G. and da Silva, J.A. and Dafsari, H.S. and Dagda, R.K. and Dagdas, Y. and Daglia, M. and Dai, X. and Dai, Y. and Dai, Y. and Dal Col, J. and Dalhaimer, P. and Dalla Valle, L. and Dallenga, T. and Dalmasso, G. and Damme, M. and Dando, I. and Dantuma, N.P. and Darling, A.L. and Das, H. and Dasarathy, S. and Dasari, S.K. and Dash, S. and Daumke, O. and Dauphinee, A.N. and Davies, J.S. and Dávila, V.A. and Davis, R.J. and Davis, T. and Dayalan Naidu, S. and De Amicis, F. and De Bosscher, K. and De Felice, F. and De Franceschi, L. and De Leonibus, C. and de Mattos Barbosa, M.G. and De Meyer, G.R.Y. and De Milito, A. and De Nunzio, C. and De Palma, C. and De Santi, M. and De Virgilio, C. and De Zio, D. and Debnath, J. and DeBosch, B.J. and Decuypere, J.P. and Deehan, M.A. and Deflorian, G. and DeGregori, J. and Dehay, B. and Del Rio, G. and Delaney, J.R. and Delbridge, L.M.D. and Delorme-Axford, E. and Delpino, M.V. and Demarchi, F. and Dembitz, V. and Demers, N.D. and Deng, H. and Deng, Z. and Dengjel, J. and Dent, P. and Denton, D. and DePamphilis, M.L. and Der, C.J. and Deretic, V. and Descoteaux, A. and Devis, L. and Devkota, S. and Devuyst, O. and Dewson, G. and Dharmasivam, M. and Dhiman, R. and di Bernardo, D. and Di Cristina, M. and Di Domenico, F. and Di Fazio, P. and Di Fonzo, A. and Di Guardo, G. and Di Guglielmo, G.M. and Di Leo, L. and Di Malta, C. and Di Nardo, A. and Di Rienzo, M. and Di Sano, F. and Diallinas, G. and Diao, J. and Diaz-Araya, G. and Díaz-Laviada, I. and Dickinson, J.M. and Diederich, M. and Dieudé, M. and Dikic, I. and Ding, S. and Ding, W.X. and Dini, L. and Dinić, J. and Dinic, M. and Dinkova-Kostova, A.T. and Dionne, M.S. and Distler, J.H.W. and Diwan, A. and Dixon, I.M.C. and Djavaheri-Mergny, M. and Dobrinski, I. and Dobrovinskaya, O. and Dobrowolski, R. and Dobson, R.C.J. and Đokić, J. and Dokmeci Emre, S. and Donadelli, M. and Dong, B. and Dong, X. and Dong, Z. and Dorn Ii, G.W. and Dotsch, V. and Dou, H. and Dou, J. and Dowaidar, M. and Dridi, S. and Drucker, L. and Du, A. and Du, C. and Du, G. and Du, H.N. and Du, L.L. and du Toit, A. and Duan, S.B. and Duan, X. and Duarte, S.P. and Dubrovska, A. and Dunlop, E.A. and Dupont, N. and Durán, R.V. and Dwarakanath, B.S. and Dyshlovoy, S.A. and Ebrahimi-Fakhari, D. and Eckhart, L. and Edelstein, C.L. and Efferth, T. and Eftekharpour, E. and Eichinger, L. and Eid, N. and Eisenberg, T. and Eissa, N.T. and Eissa, S. and Ejarque, M. and El Andaloussi, A. and El-Hage, N. and El-Naggar, S. and Eleuteri, A.M. and El-Shafey, E.S. and Elgendy, M. and Eliopoulos, A.G. and Elizalde, M.M. and Elks, P.M. and Elsasser, H.P. and Elsherbiny, E.S. and Emerling, B.M. and Emre, N.C.T. and Eng, C.H. and Engedal, N. and Engelbrecht, A.M. and Engelsen, A.S.T. and Enserink, J.M. and Escalante, R. and Esclatine, A. and Escobar-Henriques, M. and Eskelinen, E.L. and Espert, L. and Eusebio, M.O. and Fabrias, G. and Fabrizi, C. and Facchiano, A. and Facchiano, F. and Fadeel, B. and Fader, C. and Faesen, A.C. and Fairlie, W.D. and Falcó, A. and Falkenburger, B.H. and Fan, D. and Fan, J. and Fan, Y. and Fang, E.F. and Fang, Y. and Fang, Y. and Fanto, M. and Farfel-Becker, T. and Faure, M. and Fazeli, G. and Fedele, A.O. and Feldman, A.M. and Feng, D. and Feng, J. and Feng, L. and Feng, Y. and Feng, Y. and Feng, W. and Fenz Araujo, T. and Ferguson, T.A. and Fernández, A.F. and Fernandez-Checa, J.C. and Fernández-Veledo, S. and Fernie, A.R. and Ferrante, A.W. and Ferraresi, A. and Ferrari, M.F. and Ferreira, J.C.B. and Ferro-Novick, S. and Figueras, A. and Filadi, R. and Filigheddu, N. and Filippi-Chiela, E. and Filomeni, G. and Fimia, G.M. and Fineschi, V. and Finetti, F. and Finkbeiner, S. and Fisher, E.A. and Fisher, P.B. and Flamigni, F. and Fliesler, S.J. and Flo, T.H. and Florance, I. and Florey, O. and Florio, T. and Fodor, E. and Follo, C. and Fon, E.A. and Forlino, A. and Fornai, F. and Fortini, P. and Fracassi, A. and Fraldi, A. and Franco, B. and Franco, R. and Franconi, F. and Frankel, L.B. and Friedman, S.L. and Fröhlich, L.F. and Frühbeck, G. and Fuentes, J.M. and Fujiki, Y. and Fujita, N. and Fujiwara, Y. and Fukuda, M. and Fulda, S. and Furic, L. and Furuya, N. and Fusco, C. and Gack, M.U. and Gaffke, L. and Galadari, S. and Galasso, A. and Galindo, M.F. and Gallolu Kankanamalage, S. and Galluzzi, L. and Galy, V. and Gammoh, N. and Gan, B. and Ganley, I.G. and Gao, F. and Gao, H. and Gao, M. and Gao, P. and Gao, S.J. and Gao, W. and Gao, X. and Garcera, A. and Garcia, M.N. and Garcia, V.E. and García-Del Portillo, F. and Garcia-Escudero, V. and Garcia-Garcia, A. and Garcia-Macia, M. and García-Moreno, D. and Garcia-Ruiz, C. and García-Sanz, P. and Garg, A.D. and Gargini, R. and Garofalo, T. and Garry, R.F. and Gassen, N.C. and Gatica, D. and Ge, L. and Ge, W. and Geiss-Friedlander, R. and Gelfi, C. and Genschik, P. and Gentle, I.E. and Gerbino, V. and Gerhardt, C. and Germain, K. and Germain, M. and Gewirtz, D.A. and Ghasemipour Afshar, E. and Ghavami, S. and Ghigo, A. and Ghosh, M. and Giamas, G. and Giampietri, C. and Giatromanolaki, A. and Gibson, G.E. and Gibson, S.B. and Ginet, V. and Giniger, E. and Giorgi, C. and Girao, H. and Girardin, S.E. and Giridharan, M. and Giuliano, S. and Giulivi, C. and Giuriato, S. and Giustiniani, J. and Gluschko, A. and Goder, V. and Goginashvili, A. and Golab, J. and Goldstone, D.C. and Golebiewska, A. and Gomes, L.R. and Gomez, R. and Gómez-Sánchez, R. and Gomez-Puerto, M.C. and Gomez-Sintes, R. and Gong, Q. and Goni, F.M. and González-Gallego, J. and Gonzalez-Hernandez, T. and Gonzalez-Polo, R.A. and Gonzalez-Reyes, J.A. and González-Rodríguez, P. and Goping, I.S. and Gorbatyuk, M.S. and Gorbunov, N.V. and Görgülü, K. and Gorojod, R.M. and Gorski, S.M. and Goruppi, S. and Gotor, C. and Gottlieb, R.A. and Gozes, I. and Gozuacik, D. and Graef, M. and Gräler, M.H. and Granatiero, V. and Grasso, D. and Gray, J.P. and Green, D.R. and Greenhough, A. and Gregory, S.L. and Griffin, E.F. and Grinstaff, M.W. and Gros, F. and Grose, C. and Gross, A.S. and Gruber, F. and Grumati, P. and Grune, T. and Gu, X. and Guan, J.L. and Guardia, C.M. and Guda, K. and Guerra, F. and Guerri, C. and Guha, P. and Guillén, C. and Gujar, S. and Gukovskaya, A. and Gukovsky, I. and Gunst, J. and Günther, A. and Guntur, A.R. and Guo, C. and Guo, C. and Guo, H. and Guo, L.W. and Guo, M. and Gupta, P. and Gupta, S.K. and Gupta, S. and Gupta, V.B. and Gupta, V. and Gustafsson, A.B. and Gutterman, D.D. and H B, R. and Haapasalo, A. and Haber, J.E. and Hać, A. and Hadano, S. and Hafrén, A.J. and Haidar, M. and Hall, B.S. and Halldén, G. and Hamacher-Brady, A. and Hamann, A. and Hamasaki, M. and Han, W. and Hansen, M. and Hanson, P.I. and Hao, Z. and Harada, M. and Harhaji-Trajkovic, L. and Hariharan, N. and Haroon, N. and Harris, J. and Hasegawa, T. and Hasima Nagoor, N. and Haspel, J.A. and Haucke, V. and Hawkins, W.D. and Hay, B.A. and Haynes, C.M. and Hayrabedyan, S.B. and Hays, T.S. and He, C. and He, Q. and He, R.R. and He, Y.W. and He, Y.Y. and Heakal, Y. and Heberle, A.M. and Hejtmancik, J.F. and Helgason, G.V. and Henkel, V. and Herb, M. and Hergovich, A. and Herman-Antosiewicz, A. and Hernández, A. and Hernandez, C. and Hernandez-Diaz, S. and Hernandez-Gea, V. and Herpin, A. and Herreros, J. and Hervás, J.H. and Hesselson, D. and Hetz, C. and Heussler, V.T. and Higuchi, Y. and Hilfiker, S. and Hill, J.A. and Hlavacek, W.S. and Ho, E.A. and Ho, I.H.T. and Ho, P.W.L. and Ho, S.L. and Ho, W.Y. and Hobbs, G.A. and Hochstrasser, M. and Hoet, P.H.M. and Hofius, D. and Hofman, P. and Höhn, A. and Holmberg, C.I. and Hombrebueno, J.R. and Yi-Ren Hong, C.W.H. and Hooper, L.V. and Hoppe, T. and Horos, R. and Hoshida, Y. and Hsin, I.L. and Hsu, H.Y. and Hu, B. and Hu, D. and Hu, L.F. and Hu, M.C. and Hu, R. and Hu, W. and Hu, Y.C. and Hu, Z.W. and Hua, F. and Hua, J. and Hua, Y. and Huan, C. and Huang, C. and Huang, C. and Huang, C. and Huang, C. and Huang, H. and Huang, K. and Huang, M.L.H. and Huang, R. and Huang, S. and Huang, T. and Huang, X. and Huang, Y.J. and Huber, T.B. and Hubert, V. and Hubner, C.A. and Hughes, S.M. and Hughes, W.E. and Humbert, M. and Hummer, G. and Hurley, J.H. and Hussain, S. and Hussain, S. and Hussey, P.J. and Hutabarat, M. and Hwang, H.Y. and Hwang, S. and Ieni, A. and Ikeda, F. and Imagawa, Y. and Imai, Y. and Imbriano, C. and Imoto, M. and Inman, D.M. and Inoki, K. and Iovanna, J. and Iozzo, R.V. and Ippolito, G. and Irazoqui, J.E. and Iribarren, P. and Ishaq, M. and Ishikawa, M. and Ishimwe, N. and Isidoro, C. and Ismail, N. and Issazadeh-Navikas, S. and Itakura, E. and Ito, D. and Ivankovic, D. and Ivanova, S. and Iyer, A.K.V. and Izquierdo, J.M. and Izumi, M. and Jäättelä, M. and Jabir, M.S. and Jackson, W.T. and Jacobo-Herrera, N. and Jacomin, A.C. and Jacquin, E. and Jadiya, P. and Jaeschke, H. and Jagannath, C. and Jakobi, A.J. and Jakobsson, J. and Janji, B. and Jansen-Dürr, P. and Jansson, P.J. and Jantsch, J. and Januszewski, S. and Jassey, A. and Jean, S. and Jeltsch-David, H. and Jendelova, P. and Jenny, A. and Jensen, T.E. and Jessen, N. and Jewell, J.L. and Ji, J. and Jia, L. and Jia, R. and Jiang, L. and Jiang, Q. and Jiang, R. and Jiang, T. and Jiang, X. and Jiang, Y. and Jimenez-Sanchez, M. and Jin, E.J. and Jin, F. and Jin, H. and Jin, L. and Jin, L. and Jin, M. and Jin, S. and Jo, E.K. and Joffre, C. and Johansen, T. and Johnson, G.V.W. and Johnston, S.A. and Jokitalo, E. and Jolly, M.K. and Joosten, L.A.B. and Jordan, J. and Joseph, B. and Ju, D. and Ju, J.S. and Ju, J. and Juárez, E. and Judith, D. and Juhász, G. and Jun, Y. and Jung, C.H. and Jung, S.C. and Jung, Y.K. and Jungbluth, H. and Jungverdorben, J. and Just, S. and Kaarniranta, K. and Kaasik, A. and Kabuta, T. and Kaganovich, D. and Kahana, A. and Kain, R. and Kajimura, S. and Kalamvoki, M. and Kalia, M. and Kalinowski, D.S. and Kaludercic, N. and Kalvari, I. and Kaminska, J. and Kaminskyy, V.O. and Kanamori, H. and Kanasaki, K. and Kang, C. and Kang, R. and Kang, S.S. and Kaniyappan, S. and Kanki, T. and Kanneganti, T.D. and Kanthasamy, A.G. and Kanthasamy, A. and Kantorow, M. and Kapuy, O. and Karamouzis, M.V. and Karim, M.D.R. and Karmakar, P. and Katare, R.G. and Kato, M. and Kaufmann, S.H.E. and Kauppinen, A. and Kaushal, G.P. and Kaushik, S. and Kawasaki, K. and Kazan, K. and Ke, P.Y. and Keating, D.J. and Keber, U. and Kehrl, J.H. and Keller, K.E. and Keller, C.W. and Kemper, J.K. and Kenific, C.M. and Kepp, O. and Kermorgant, S. and Kern, A. and Ketteler, R. and Keulers, T.G. and Khalfin, B. and Khalil, H. and Khambu, B. and Khan, S.Y. and Khandelwal, V.K.M. and Khandia, R. and Kho, W. and Khobrekar, N.V. and Khuansuwan, S. and Khundadze, M. and Killackey, S.A. and Kim, D. and Kim, D.R. and Kim, D.H. and Kim, D.E. and Kim, E.Y. and Kim, E.K. and Kim, H.R. and Kim, H.S. and Kim, H.R. and Kim, J.H. and Kim, J.K. and Kim, J.H. and Kim, J. and Kim, J.H. and Kim, K.I.I. and Kim, P.K. and Kim, S.J. and Kimball, S.R. and Kimchi, A. and Kimmelman, A.C. and Kimura, T. and King, M.A. and Kinghorn, K.J. and Kinsey, C.G. and Kirkin, V. and Kirshenbaum, L.A. and Kiselev, S.L. and Kishi, S. and Kitamoto, K. and Kitaoka, Y. and Kitazato, K. and Kitsis, R.N. and Kittler, J.T. and Kjaerulff, O. and Klein, P.S. and Klopstock, T. and Klucken, J. and Knævelsrud, H. and Knorr, R.L. and Ko, B.C.B. and Ko, F. and Ko, J.L. and Kobayashi, H. and Kobayashi, S. and Koch, I. and Koch, J.C. and Koenig, U. and Kögel, D. and Koh, Y.H. and Koike, M. and Kohlwein, S.D. and Kocaturk, N.M. and Komatsu, M. and König, J. and Kono, T. and Kopp, B.T. and Korcsmaros, T. and Korkmaz, G. and Korolchuk, V.I. and Korsnes, M.S. and Koskela, A. and Kota, J. and Kotake, Y. and Kotler, M.L. and Kou, Y. and Koukourakis, M.I. and Koustas, E. and Kovacs, A.L. and Kovács, T. and Koya, D. and Kozako, T. and Kraft, C. and Krainc, D. and Krämer, H. and Krasnodembskaya, A.D. and Kretz-Remy, C. and Kroemer, G. and Ktistakis, N.T. and Kuchitsu, K. and Kuenen, S. and Kuerschner, L. and Kukar, T. and Kumar, A. and Kumar, A. and Kumar, D. and Kumar, D. and Kumar, S. and Kume, S. and Kumsta, C. and Kundu, C.N. and Kundu, M. and Kunnumakkara, A.B. and Kurgan, L. and Kutateladze, T.G. and Kutlu, O. and Kwak, S.A. and Kwon, H.J. and Kwon, T.K. and Kwon, Y.T. and Kyrmizi, I. and La Spada, A. and Labonté, P. and Ladoire, S. and Laface, I. and Lafont, F. and Lagace, D.C. and Lahiri, V. and Lai, Z. and Laird, A.S. and Lakkaraju, A. and Lamark, T. and Lan, S.H. and Landajuela, A. and Lane, D.J.R. and Lane, J.D. and Lang, C.H. and Lange, C. and Langel, Ü. and Langer, R. and Lapaquette, P. and Laporte, J. and LaRusso, N.F. and Lastres-Becker, I. and Lau, W.C.Y. and Laurie, G.W. and Lavandero, S. and Law, B.Y.K. and Law, H.K.W. and Layfield, R. and Le, W. and Le Stunff, H. and Leary, A.Y. and Lebrun, J.J. and Leck, L.Y.W. and Leduc-Gaudet, J.P. and Lee, C. and Lee, C.P. and Lee, D.H. and Lee, E.B. and Lee, E.F. and Lee, G.M. and Lee, H.J. and Lee, H.K. and Lee, J.M. and Lee, J.S. and Lee, J.A. and Lee, J.Y. and Lee, J.H. and Lee, M. and Lee, M.G. and Lee, M.J. and Lee, M.S. and Lee, S.Y. and Lee, S.J. and Lee, S.Y. and Lee, S.B. and Lee, W.H. and Lee, Y.R. and Lee, Y.H. and Lee, Y. and Lefebvre, C. and Legouis, R. and Lei, Y.L. and Lei, Y. and Leikin, S. and Leitinger, G. and Lemus, L. and Leng, S. and Lenoir, O. and Lenz, G. and Lenz, H.J. and Lenzi, P. and León, Y. and Leopoldino, A.M. and Leschczyk, C. and Leskelä, S. and Letellier, E. and Leung, C.T. and Leung, P.S. and Leventhal, J.S. and Levine, B. and Lewis, P.A. and Ley, K. and Li, B. and Li, D.Q. and Li, J. and Li, J. and Li, J. and Li, K. and Li, L. and Li, M. and Li, M. and Li, M. and Li, M. and Li, M. and Li, P.L. and Li, M.Q. and Li, Q. and Li, S. and Li, T. and Li, W. and Li, W. and Li, X. and Li, Y.P. and Li, Y. and Li, Z. and Li, Z. and Li, Z. and Lian, J. and Liang, C. and Liang, Q. and Liang, W. and Liang, Y. and Liang, Y.T. and Liao, G. and Liao, L. and Liao, M. and Liao, Y.F. and Librizzi, M. and Lie, P.P.Y. and Lilly, M.A. and Lim, H.J. and Lima, T.R.R. and Limana, F. and Lin, C. and Lin, C.W. and Lin, D.S. and Lin, F.C. and Lin, J.D. and Lin, K.M. and Lin, K.H. and Lin, L.T. and Lin, P.H. and Lin, Q. and Lin, S. and Lin, S.J. and Lin, W. and Lin, X. and Lin, Y.X. and Lin, Y.S. and Linden, R. and Lindner, P. and Ling, S.C. and Lingor, P. and Linnemann, A.K. and Liou, Y.C. and Lipinski, M.M. and Lipovšek, S. and Lira, V.A. and Lisiak, N. and Liton, P.B. and Liu, C. and Liu, C.H. and Liu, C.F. and Liu, C.H. and Liu, F. and Liu, H. and Liu, H.S. and Liu, H.F. and Liu, H. and Liu, J. and Liu, J. and Liu, J. and Liu, L. and Liu, L. and Liu, M. and Liu, Q. and Liu, W. and Liu, W. and Liu, X.H. and Liu, X. and Liu, X. and Liu, X. and Liu, X. and Liu, Y. and Liu, Y. and Liu, Y. and Liu, Y. and Liu, Y. and Livingston, J.A. and Lizard, G. and Lizcano, J.M. and Ljubojevic-Holzer, S. and LLeonart, M.E. and Llobet-Navàs, D. and Llorente, A. and Lo, C.H. and Lobato-Márquez, D. and Long, Q. and Long, Y.C. and Loos, B. and Loos, J.A. and López, M.G. and López-Doménech, G. and López-Guerrero, J.A. and López-Jiménez, A.T. and López-Pérez, O. and López-Valero, I. and Lorenowicz, M.J. and Lorente, M. and Lorincz, P. and Lossi, L. and Lotersztajn, S. and Lovat, P.E. and Lovell, J.F. and Lovy, A. and Lőw, P. and Lu, G. and Lu, H. and Lu, J.H. and Lu, J.J. and Lu, M. and Lu, S. and Luciani, A. and Lucocq, J.M. and Ludovico, P. and Luftig, M.A. and Luhr, M. and Luis-Ravelo, D. and Lum, J.J. and Luna-Dulcey, L. and Lund, A.H. and Lund, V.K. and Lünemann, J.D. and Lüningschrör, P. and Luo, H. and Luo, R. and Luo, S. and Luo, Z. and Luparello, C. and Lüscher, B. and Luu, L. and Lyakhovich, A. and Lyamzaev, K.G. and Lystad, A.H. and Lytvynchuk, L. and Ma, A.C. and Ma, C. and Ma, M. and Ma, N.F. and Ma, Q.H. and Ma, X. and Ma, Y. and Ma, Z. and MacDougald, O.A. and Macian, F. and MacIntosh, G.C. and MacKeigan, J.P. and Macleod, K.F. and Maday, S. and Madeo, F. and Madesh, M. and Madl, T. and Madrigal-Matute, J. and Maeda, A. and Maejima, Y. and Magarinos, M. and Mahavadi, P. and Maiani, E. and Maiese, K. and Maiti, P. and Maiuri, M.C. and Majello, B. and Major, M.B. and Makareeva, E. and Malik, F. and Mallilankaraman, K. and Malorni, W. and Maloyan, A. and Mammadova, N. and Man, G.C.W. and Manai, F. and Mancias, J.D. and Mandelkow, E.M. and Mandell, M.A. and Manfredi, A.A. and Manjili, M.H. and Manjithaya, R. and Manque, P. and Manshian, B.B. and Manzano, R. and Manzoni, C. and Mao, K. and Marchese, C. and Marchetti, S. and Marconi, A.M. and Marcucci, F. and Mardente, S. and Mareninova, O.A. and Margeta, M. and Mari, M. and Marinelli, S. and Marinelli, O. and Mariño, G. and Mariotto, S. and Marshall, R.S. and Marten, M.R. and Martens, S. and Martin, A.P.J. and Martin, K.R. and Martin, S. and Martin, S. and Martín-Segura, A. and Martín-Acebes, M.A. and Martin-Burriel, I. and Martin-Rincon, M. and Martin-Sanz, P. and Martina, J.A. and Martinet, W. and Martinez, A. and Martinez, A. and Martinez, J. and Martinez Velazquez, M. and Martinez-Lopez, N. and Martinez-Vicente, M. and Martins, D.O. and Martins, J.O. and Martins, W.K. and Martins-Marques, T. and Marzetti, E. and Masaldan, S. and Masclaux-Daubresse, C. and Mashek, D.G. and Massa, V. and Massieu, L. and Masson, G.R. and Masuelli, L. and Masyuk, A.I. and Masyuk, T.V. and Matarrese, P. and Matheu, A. and Matoba, S. and Matsuzaki, S. and Mattar, P. and Matte, A. and Mattoscio, D. and Mauriz, J.L. and Mauthe, M. and Mauvezin, C. and Maverakis, E. and Maycotte, P. and Mayer, J. and Mazzoccoli, G. and Mazzoni, C. and Mazzulli, J.R. and McCarty, N. and McDonald, C. and McGill, M.R. and McKenna, S.L. and McLaughlin, B.A. and McLoughlin, F. and McNiven, M.A. and McWilliams, T.G. and Mechta-Grigoriou, F. and Medeiros, T.C. and Medina, D.L. and Megeney, L.Y. and Megyeri, K. and Mehrpour, M. and Mehta, J.L. and Meijer, A.J. and Meijer, A.H. and Mejlvang, J. and Meléndez, A. and Melk, A. and Memisoglu, G. and Mendes, A.F. and Meng, D. and Meng, F. and Meng, T. and Menna-Barreto, R. and Menon, M.B. and Mercer, C. and Mercier, A.E. and Mergny, J.L. and Merighi, A. and Merkley, S.D. and Merla, G. and Meske, V. and Mestre, A.C. and Metur, S.P. and Meyer, C. and Meyer, H. and Mi, W. and Mialet-Perez, J. and Miao, J. and Micale, L. and Miki, Y. and Milan, E. and Milczarek, M. and Miller, D.L. and Miller, S.I. and Miller, S. and Millward, S.W. and Milosevic, I. and Minina, E.A. and Mirzaei, H. and Mirzaei, H.R. and Mirzaei, M. and Mishra, A. and Mishra, N. and Mishra, P.K. and Misirkic Marjanovic, M. and Misasi, R. and Misra, A. and Misso, G. and Mitchell, C. and Mitou, G. and Miura, T. and Miyamoto, S. and Miyazaki, M. and Miyazaki, M. and Miyazaki, T. and Miyazawa, K. and Mizushima, N. and Mogensen, T.H. and Mograbi, B. and Mohammadinejad, R. and Mohamud, Y. and Mohanty, A. and Mohapatra, S. and Möhlmann, T. and Mohmmed, A. and Moles, A. and Moley, K.H. and Molinari, M. and Mollace, V. and Møller, A.B. and Mollereau, B. and Mollinedo, F. and Montagna, C. and Monteiro, M.J. and Montella, A. and Montes, L.R. and Montico, B. and Mony, V.K. and Monzio Compagnoni, G. and Moore, M.N. and Moosavi, M.A. and Mora, A.L. and Mora, M. and Morales-Alamo, D. and Moratalla, R. and Moreira, P.I. and Morelli, E. and Moreno, S. and Moreno-Blas, D. and Moresi, V. and Morga, B. and Morgan, A.H. and Morin, F. and Morishita, H. and Moritz, O.L. and Moriyama, M. and Moriyasu, Y. and Morleo, M. and Morselli, E. and Moruno-Manchon, J.F. and Moscat, J. and Mostowy, S. and Motori, E. and Moura, A.F. and Moustaid-Moussa, N. and Mrakovcic, M. and Muciño-Hernández, G. and Mukherjee, A. and Mukhopadhyay, S. and Mulcahy Levy, J.M. and Mulero, V. and Muller, S. and Münch, C. and Munjal, A. and Munoz-Canoves, P. and Muñoz-Galdeano, T. and Münz, C. and Murakawa, T. and Muratori, C. and Murphy, B.M. and Murphy, J.P. and Murthy, A. and Myöhänen, T.T. and Mysorekar, I.U. and Mytych, J. and Nabavi, S.M. and Nabissi, M. and Nagy, P. and Nah, J. and Nahimana, A. and Nakagawa, I. and Nakamura, K. and Nakatogawa, H. and Nandi, S.S. and Nanjundan, M. and Nanni, M. and Napolitano, G. and Nardacci, R. and Narita, M. and Nassif, M. and Nathan, I. and Natsumeda, M. and Naude, R.J. and Naumann, C. and Naveiras, O. and Navid, F. and Nawrocki, S.T. and Nazarko, T.Y. and Nazio, F. and Negoita, F. and Neill, T. and Neisch, A.L. and Neri, L.M. and Netea, M.G. and Neubert, P. and Neufeld, T.P. and Neumann, D. and Neutzner, A. and Newton, P.T. and Ney, P.A. and Nezis, I.P. and Ng, C.C.W. and Ng, T.B. and Nguyen, H.T.T. and Nguyen, L.T. and Ni, H.M. and Ní Cheallaigh, C. and Ni, Z. and Nicolao, M.C. and Nicoli, F. and Nieto-Diaz, M. and Nilsson, P. and Ning, S. and Niranjan, R. and Nishimune, H. and Niso-Santano, M. and Nixon, R.A. and Nobili, A. and Nobrega, C. and Noda, T. and Nogueira-Recalde, U. and Nolan, T.M. and Nombela, I. and Novak, I. and Novoa, B. and Nozawa, T. and Nukina, N. and Nussbaum-Krammer, C. and Nylandsted, J. and O'Donovan, T.R. and O'Leary, S.M. and O'Rourke, E.J. and O'Sullivan, M.P. and O'Sullivan, T.E. and Oddo, S. and Oehme, I. and Ogawa, M. and Ogier-Denis, E. and Ogmundsdottir, M.H. and Ogretmen, B. and Oh, G.T. and Oh, S.H. and Oh, Y.J. and Ohama, T. and Ohashi, Y. and Ohmuraya, M. and Oikonomou, V. and Ojha, R. and Okamoto, K. and Okazawa, H. and Oku, M. and Oliván, S. and Oliveira, J.M.A. and Ollmann, M. and Olzmann, J.A. and Omari, S. and Omary, M.B. and Önal, G. and Ondrej, M. and Ong, S.B. and Ong, S.G. and Onnis, A. and Orellana, J.A. and Orellana-Muñoz, S. and Ortega-Villaizan, M.D.M. and Ortiz-Gonzalez, X.R. and Ortona, E. and Osiewacz, H.D. and Osman, A.H.K. and Osta, R. and Otegui, M.S. and Otsu, K. and Ott, C. and Ottobrini, L. and Ou, J.H.J. and Outeiro, T.F. and Oynebraten, I. and Ozturk, M. and Pagès, G. and Pahari, S. and Pajares, M. and Pajvani, U.B. and Pal, R. and Paladino, S. and Pallet, N. and Palmieri, M. and Palmisano, G. and Palumbo, C. and Pampaloni, F. and Pan, L. and Pan, Q. and Pan, W: and Pan, X. and Panasyuk, G. and Pandey, R. and Pandey, U.B. and Pandya, V. and Paneni, F. and Pang, S.Y. and Panzarini, E. and Papademetrio, D.L. and Papaleo, E. and Papinski, D. and Papp, D. and Park, E.C. and Park, H.T. and Park, J.M. and Park, J.I. and Park, J.T. and Park, J. and Park, S.C. and Park, S.Y. and Parola, A.H. and Parys, J.B. and Pasquier, A. and Pasquier, B. and Passos, J.F. and Pastore, N. and Patel, H.H. and Patschan, D. and Pattingre, S. and Pedraza-Alva, G. and Pedraza-Chaverri, J. and Pedrozo, Z. and Pei, G. and Pei, J. and Peled-Zehavi, H. and Pellegrini, J.M. and Pelletier, J. and Peñalva, M.A. and Peng, D. and Peng, Y. and Penna, F. and Pennuto, M. and Pentimalli, F. and Pereira, C.M.F. and Pereira, G.J.S. and Pereira, L.C. and Pereira de Almeida, L. and Perera, N.D. and Pérez-Lara, A. and Perez-Oliva, A.B. and Pérez-Pérez, M.E. and Periyasamy, P. and Perl, A. and Perrotta, C. and Perrotta, I. and Pestell, R.G. and Petersen, M. and Petrache, I. and Petrovski, G. and Pfirrmann, T. and Pfister, A.S. and Philips, J.A. and Pi, H. and Picca, A. and Pickrell, A.M. and Picot, S. and Pierantoni, G.M. and Pierdominici, M. and Pierre, P. and Pierrefite-Carle, V. and Pierzynowska, K. and Pietrocola, F. and Pietruczuk, M. and Pignata, C. and Pimentel-Muiños, F.X. and Pinar, M. and Pinheiro, R.O. and Pinkas-Kramarski, R. and Pinton, P. and Pircs, K. and Piya, S. and Pizzo, P. and Plantinga, T.S. and Platta, H.W. and Plaza-Zabala, A. and Plomann, M. and Plotnikov, E.Y. and Plun-Favreau, H. and Pluta, R. and Pocock, R. and Pöggeler, S. and Pohl, C. and Poirot, M. and Poletti, A. and Ponpuak, M. and Popelka, H. and Popova, B. and Porta, H. and Porte Alcon, S. and Portilla-Fernandez, E. and Post, M. and Potts, M.B. and Poulton, J. and Powers, T. and Prahlad, V. and Prajsnar, T.K. and Praticò, D. and Prencipe, R. and Priault, M. and Proikas-Cezanne, T. and Promponas, V.J. and Proud, C.G. and Puertollano, R. and Puglielli, L. and Pulinilkunnil, T. and Puri, D. and Puri, R. and Puyal, J. and Qi, X. and Qi, Y. and Qian, W. and Qiang, L. and Qiu, Y. and Quadrilatero, J. and Quarleri, J. and Raben, N. and Rabinowich, H. and Ragona, D. and Ragusa, M.J. and Rahimi, N. and Rahmati, M. and Raia, V. and Raimundo, N. and Rajasekaran, N.S. and Ramachandra Rao, S. and Rami, A. and Ramírez-Pardo, I. and Ramsden, D.B. and Randow, F. and Rangarajan, P.N. and Ranieri, D. and Rao, H. and Rao, L. and Rao, R. and Rathore, S. and Ratnayaka, J.A. and Ratovitski, E.A. and Ravanan, P. and Ravegnini, G. and Ray, S.K. and Razani, B. and Rebecca, V. and Reggiori, F. and Régnier-Vigouroux, A. and Reichert, A.S. and Reigada, D. and Reiling, J.H. and Rein, T. and Reipert, S. and Rekha, R.S. and Ren, H. and Ren, J. and Ren, W. and Renault, T. and Renga, G. and Reue, K. and Rewitz, K. and Ribeiro de Andrade Ramos, B. and Riazuddin, S.A. and Ribeiro-Rodrigues, T.M. and Ricci, J.E. and Ricci, R. and Riccio, V. and Richardson, D.R. and Rikihisa, Y. and Risbud, M.V. and Risueño, R.M. and Ritis, K. and Rizza, S. and Rizzuto, R. and Roberts, H.C. and Roberts, L.D. and Robinson, K.J. and Roccheri, M.C. and Rocchi, S. and Rodney, G.G. and Rodrigues, T. and Rodrigues Silva, V.R. and Rodriguez, A. and Rodriguez-Barrueco, R. and Rodriguez-Henche, N. and Rodriguez-Rocha, H. and Roelofs, J. and Rogers, R.S. and Rogov, V.V. and Rojo, A.I. and Rolka, K. and Romanello, V. and Romani, L. and Romano, A. and Romano, P.S. and Romeo-Guitart, D. and Romero, L.C. and Romero, M. and Roney, J.C. and Rongo, C. and Roperto, S. and Rosenfeldt, M.T. and Rosenstiel, P. and Rosenwald, A.G. and Roth, K.A. and Roth, L. and Roth, S. and Rouschop, K.M.A. and Roussel, B.D. and Roux, S. and Rovere-Querini, P. and Roy, A. and Rozieres, A. and Ruano, D. and Rubinsztein, D.C. and Rubtsova, M.P. and Ruckdeschel, K. and Ruckenstuhl, C. and Rudolf, E. and Rudolf, R. and Ruggieri, A. and Ruparelia, A.A. and Rusmini, P. and Russell, R.R. and Russo, G.L. and Russo, M. and Russo, R. and Ryabaya, O.O. and Ryan, K.M. and Ryu, K.Y. and Sabater-Arcis, M. and Sachdev, U. and Sacher, M. and Sachse, C. and Sadhu, A. and Sadoshima, J. and Safren, N. and Saftig, P. and Sagona, A.P. and Sahay, G. and Sahebkar, A. and Sahin, M. and Sahin, O. and Sahni, S. and Saito, N. and Saito, S. and Saito, T. and Sakai, R. and Sakai, Y. and Sakamaki, J.I. and Saksela, K. and Salazar, G. and Salazar-Degracia, A. and Salekdeh, G.H. and Saluja, A.K. and Sampaio-Marques, B. and Sanchez, M.C. and Sanchez-Alcazar, J.A. and Sanchez-Vera, V. and Sancho-Shimizu, V. and Sanderson, J.T. and Sandri, M. and Santaguida, S. and Santambrogio, L. and Santana, M.M. and Santoni, G. and Sanz, A. and Sanz, P. and Saran, S. and Sardiello, M. and Sargeant, T.J. and Sarin, A. and Sarkar, C. and Sarkar, S. and Sarrias, M.R. and Sarkar, S. and Sarmah, D.T. and Sarparanta, J. and Sathyanarayan, A. and Sathyanarayanan, R. and Scaglione, K.M. and Scatozza, F. and Schaefer, L. and Schafer, Z.T. and Schaible, U.E. and Schapira, A.H.V. and Scharl, M. and Schatzl, H.M. and Schein, C.H. and Scheper, W. and Scheuring, D. and Schiaffino, M.V. and Schiappacassi, M. and Schindl, R. and Schlattner, U. and Schmidt, O. and Schmitt, R. and Schmidt, S.D. and Schmitz, I. and Schmukler, E. and Schneider, A. and Schneider, B.E. and Schober, R. and Schoijet, A.C. and Schott, M.B. and Schramm, M. and Schröder, B. and Schuh, K. and Schüller, C. and Schulze, R.L. and Schürmanns, L. and Schwamborn, J.C. and Schwarten, M. and Scialo, F. and Sciarretta, S. and Scott, M.J. and Scotto, K.W. and Scovassi, A.I. and Scrima, A. and Scrivo, A. and Sebastian, D. and Sebti, S. and Sedej, S. and Segatori, L. and Segev, N. and Seglen, P.O. and Seiliez, I. and Seki, E. and Selleck, S.B. and Sellke, F.W. and Selsby, J.T. and Sendtner, M. and Senturk, S. and Seranova, E. and Sergi, C. and Serra-Moreno, R. and Sesaki, H. and Settembre, C. and Setty, S.R.G. and Sgarbi, G. and Sha, O. and Shacka, J.J. and Shah, J.A. and Shang, D. and Shao, C. and Shao, F. and Sharbati, S. and Sharkey, L.M. and Sharma, D. and Sharma, G. and Sharma, K. and Sharma, P. and Sharma, S. and Shen, H.M. and Shen, H. and Shen, J. and Shen, M. and Shen, W. and Shen, Z. and Sheng, R. and Sheng, Z. and Sheng, Z.H. and Shi, J. and Shi, X. and Shi, Y.H. and Shiba-Fukushima, K. and Shieh, J.J. and Shimada, Y. and Shimizu, S. and Shimozawa, M. and Shintani, T. and Shoemaker, C.J. and Shojaei, S. and Shoji, I. and Shravage, B.V. and Shridhar, V. and Shu, C.W. and Shu, H.B. and Shui, K. and Shukla, A.K. and Shutt, T.E. and Sica, V. and Siddiqui, A. and Sierra, A. and Sierra-Torre, V. and Signorelli, S. and Sil, P. and Silva, B.J.A. and Silva, J.D. and Silva-Pavez, E. and Silvente-Poirot, S. and Simmonds, R.E. and Simon, A.K. and Simon, H.U. and Simons, M. and Singh, A. and Singh, L.P. and Singh, R. and Singh, S.V. and Singh, S.K. and Singh, S.B. and Singh, S. and Singh, S.P. and Sinha, D. and Sinha, R.A. and Sinha, S. and Sirko, A. and Sirohi, K. and Sivridis, E.L. and Skendros, P. and Skirycz, A. and Slaninová, I. and Smaili, S.S. and Smertenko, A. and Smith, M.D. and Soenen, S.J. and Sohn, E.J. and Sok, S.P.M. and Solaini, G. and Soldati, T. and Soleimanpour, S.A. and Soler, R.M. and Solovchenko, A. and Somarelli, J.A. and Sonawane, A. and Song, F. and Song, H.K. and Song, J.X. and Song, K. and Song, Z. and Soria, L.R. and Sorice, M. and Soukas, A.A. and Soukup, S.F. and Sousa, D. and Sousa, N. and Spagnuolo, P.A. and Spector, S.A. and Srinivas Bharath, M.M. and St Clair, D. and Stagni, V. and Staiano, L. and Stalnecker, C.A. and Stankov, M.V. and Stathopulos, P.B. and Stefan, K. and Stefan, S.M. and Stefanis, L. and Steffan, J.S. and Steinkasserer, A. and Stenmark, H. and Sterneckert, J. and Stevens, C. and Stoka, V. and Storch, S. and Stork, B. and Strappazzon, F. and Strohecker, A.M. and Stupack, D.G. and Su, H. and Su, L.Yy and Su, L. and Suarez-Fontes, A.M. and Subauste, C.S. and Subbian, S. and Subirada, P.V. and Sudhandiran, G. and Sue, C.M. and Sui, X. and Summers, C. and Sun, G. and Sun, J. and Sun, K. and Sun, M.X. and Sun, Q. and Sun, Y. and Sun, Z. and Sunahara, K.K.S. and Sundberg, E. and Susztak, K. and Sutovsky, P. and Suzuki, H. and Sweeney, G. and Symons, J.D. and Sze, S.C.W. and Szewczyk, N.J. and Tabęcka-Łonczynska, A. and Tabolacci, C. and Tacke, F. and Taegtmeyer, H. and Tafani, M. and Tagaya, M. and Tai, H. and Tait, S.W.G. and Takahashi, Y. and Takats, S. and Talwar, P. and Tam, C. and Tam, S.Y. and Tampellini, D. and Tamura, A. and Tan, C.T. and Tan, E.K. and Tan, Y.Q. and Tanaka, M. and Tanaka, M. and Tang, D. and Tang, J. and Tang, T.S. and Tanida, I. and Tao, Z. and Taouis, M. and Tatenhorst, L. and Tavernarakis, N. and Taylor, A. and Taylor, G.A. and Taylor, J.M. and Tchetina, E. and Tee, A.R. and Tegeder, I. and Teis, D. and Teixeira, N. and Teixeira-Clerc, F. and Tekirdag, K.A. and Tencomnao, T. and Tenreiro, S. and Tepikin, A.V. and Testillano, P.S. and Tettamanti, G. and Tharaux, P.L. and Thedieck, K. and Thekkinghat, A.A. and Thellung, S. and Thinwa, J.W. and Thirumalaikumar, V.P. and Thomas, S.M. and Thomes, P.G. and Thorburn, A. and Thukral, L. and Thum, T. and Thumm, M. and Tian, L. and Tichy, A. and Till, A. and Timmerman, V. and Titorenko, V.I. and Todi, S.V. and Todorova, K. and Toivonen, J.M. and Tomaipitinca, L. and Tomar, D. and Tomas-Zapico, C. and Tomić, S. and Tong, B.C.K. and Tong, C. and Tong, X. and Tooze, S.A. and Torgersen, M.L. and Torii, S. and Torres-López, L. and Torriglia, A. and Towers, C.G. and Towns, R. and Toyokuni, S. and Trajkovic, V. and Tramontano, D. and Tran, Q.G. and Travassos, L.H. and Trelford, C.B. and Tremel, S. and Trougakos, I.P. and Tsao, B.P. and Tschan, M.P. and Tse, H.F. and Tse, T.F. and Tsugawa, H. and Tsvetkov, A.S. and Tumbarello, D.A. and Tumtas, Y. and Tuñón, M.J. and Turcotte, S. and Turk, B. and Turk, V. and Turner, B.J. and Tuxworth, R.I. and Tyler, J.K. and Tyutereva, E.V. and Uchiyama, Y. and Ugun-Klusek, A. and Uhlig, H.H. and Ułamek-Kozioł, M. and Ulasov, I.V. and Umekawa, M. and Ungermann, C. and Unno, R. and Urbe, S. and Uribe-Carretero, E. and Üstün, S. and Uversky, V.N. and Vaccari, T. and Vaccaro, M.I. and Vahsen, B.F. and Vakifahmetoglu-Norberg, H. and Valdor, R. and Valente, M.J. and Valko, A. and Vallee, R.B. and Valverde, A.M. and Van den Berghe, G. and van der Veen, S. and Van Kaer, L. and van Loosdregt, J. and van Wijk, S.J.L. and Vandenberghe, W. and Vanhorebeek, I. and Vannier-Santos, M.A. and Vannini, N. and Vanrell, M.C. and Vantaggiato, C. and Varano, G. and Varela-Nieto, I. and Varga, M. and Vasconcelos, M.H. and Vats, S. and Vavvas, D.G. and Vega-Naredo, I. and Vega-Rubin-de-Celis, S. and Velasco, G. and Velázquez, A.P. and Vellai, T. and Vellenga, E. and Velotti, F. and Verdier, M. and Verginis, P. and Vergne, I. and Verkade, P. and Verma, M. and Verstreken, P. and Vervliet, T. and Vervoorts, J. and Vessoni, A.T. and Victor, V.M. and Vidal, M. and Vidoni, C. and Vieira, O.V. and Vierstra, R.D. and Viganó, S. and Vihinen, H. and Vijayan, V. and Vila, M. and Vilar, M. and Villalba, J.M. and Villalobo, A. and Villarejo-Zori, B. and Villarroya, F. and Villarroya, J. and Vincent, O. and Vindis, C. and Viret, C. and Viscomi, M.T. and Visnjic, D. and Vitale, I. and Vocadlo, D.J. and Voitsekhovskaja, O.V. and Volonté, C. and Volta, M. and Vomero, M. and Von Haefen, C. and Vooijs, M.A. and Voos, W. and Vucicevic, L. and Wade-Martins, R. and Waguri, S. and Waite, K.A. and Wakatsuki, S. and Walker, D.W. and Walker, M.J. and Walker, S.A. and Walter, J. and Wandosell, F.G. and Wang, B. and Wang, C.Y. and Wang, C. and Wang, C. and Wang, C. and Wang, C.Y. and Wang, D. and Wang, F. and Wang, F. and Wang, F. and Wang, G. and Wang, H. and Wang, H. and Wang, H. and Wang, H.G. and Wang, J. and Wang, J. and Wang, J. and Wang, J. and Wang, K. and Wang, L. and Wang, L. and Wang, M.H. and Wang, M. and Wang, N. and Wang, P. and Wang, P. and Wang, P. and Wang, P. and Wang, Q.J. and Wang, Q. and Wang, Q.K. and Wang, Q.A. and Wang, W.T. and Wang, W. and Wang, X. and Wang, X. and Wang, Y. and Wang, Y. and Wang, Y. and Wang, Y.Y. and Wang, Y. and Wang, Y. and Wang, Y. and Wang, Y. and Wang, Z. and Wang, Z. and Wang, Z. and Warnes, G. and Warnsmann, V. and Watada, H. and Watanabe, E. and Watchon, M. and Wawrzyńska, A. and Weaver, T.E. and Wegrzyn, G. and Wehman, A.M. and Wei, H. and Wei, L. and Wei, T. and Wei, Y. and Weiergräber, O.H. and Weihl, C.C. and Weindl, G. and Weiskirchen, R. and Wells, A. and Wen, R.H. and Wen, X. and Werner, A. and Weykopf, B. and Wheatley, S.P. and Whitton, J.L. and Whitworth, A.J. and Wiktorska, K. and Wildenberg, M.E. and Wileman, T. and Wilkinson, S. and Willbold, D. and Williams, B. and Williams, R.S.B. and Williams, R.L. and Williamson, P.R. and Wilson, R.A. and Winner, B. and Winsor, N.J. and Witkin, S.S. and Wodrich, H. and Woehlbier, U. and Wollert, T. and Wong, E. and Wong, J.H. and Wong, R.W. and Wong, V.K.W. and Wong, W.L. and Wu, A.G. and Wu, C. and Wu, J. and Wu, J. and Wu, K.K. and Wu, M. and Wu, S.Y. and Wu, S. and Wu, S.Y. and Wu, S. and Wu, W.K.K. and Wu, X. and Wu, X. and Wu, Y.W. and Wu, Y. and Xavier, R.J. and Xia, H. and Xia, L. and Xia, Z. and Xiang, G. and Xiang, J. and Xiang, M. and Xiang, W. and Xiao, B. and Xiao, G. and Xiao, H. and Xiao, H.T. and Xiao, J. and Xiao, L. and Xiao, S. and Xiao, Y. and Xie, B. and Xie, C.M. and Xie, M. and Xie, Y. and Xie, Z. and Xie, Z. and Xilouri, M. and Xu, C. and Xu, E. and Xu, H. and Xu, J. and Xu, J.R. and Xu, L. and Xu, W.W. and Xu, X. and Xue, Y. and Yakhine-Diop, S.M.S. and Yamaguchi, M. and Yamaguchi, O. and Yamamoto, A. and Yamashina, S. and Yan, S. and Yan, S.J. and Yan, Z. and Yanagi, Y. and Yang, C. and Yang, D.S. and Yang, H. and Yang, H.T. and Yang, H. and Yang, J.M. and Yang, J. and Yang, J. and Yang, L. and Yang, L. and Yang, M. and Yang, P.M. and Yang, Q. and Yang, S. and Yang, S. and Yang, S.F. and Yang, W. and Yang, W.Y. and Yang, X. and Yang, X. and Yang, Y. and Yang, Y. and Yao, H. and Yao, S. and Yao, X. and Yao, Y.G. and Yao, Y.M. and Yasui, T. and Yazdankhah, M. and Yen, P.M. and Yi, C. and Yin, X.M. and Yin, Y. and Yin, Z. and Yin, Z. and Ying, M. and Ying, Z. and Yip, C.K. and Yiu, S.P.T. and Yoo, Y.H. and Yoshida, K. and Yoshii, S.R. and Yoshimori, T. and Yousefi, B. and Yu, B. and Yu, H. and Yu, J. and Yu, J. and Yu, L. and Yu, M.L. and Yu, S.W. and Yu, V.C. and Yu, W.H. and Yu, Z. and Yu, Z. and Yuan, J. and Yuan, L.Q. and Yuan, S. and Yuan, S.S.F. and Yuan, Y. and Yuan, Z. and Yue, J. and Yue, Z. and Yun, J. and Yung, R.L. and Zacks, D.N. and Zaffagnini, G. and Zambelli, V.O. and Zanella, I. and Zang, Q.S. and Zanivan, S. and Zappavigna, S. and Zaragoza, P. and Zarbalis, K.S. and Zarebkohan, A. and Zarrouk, A. and Zeitlin, S.O. and Zeng, J. and Zeng, J.D. and Žerovnik, E. and Zhan, L. and Zhang, B. and Zhang, D.D. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H. and Zhang, H.L. and Zhang, J. and Zhang, J. and Zhang, J.P. and Zhang, K.Y.B. and Zhang, L.W. and Zhang, L. and Zhang, L. and Zhang, L. and Zhang, L. and Zhang, M. and Zhang, P. and Zhang, S. and Zhang, W. and Zhang, X. and Zhang, X.W. and Zhang, X. and Zhang, X. and Zhang, X. and Zhang, X. and Zhang, X.D. and Zhang, Y. and Zhang, Y. and Zhang, Y. and Zhang, Y.D. and Zhang, Y. and Zhang, Y.Y. and Zhang, Y. and Zhang, Z. and Zhang, Z. and Zhang, Z. and Zhang, Z. and Zhang, Z. and Zhang, Z. and Zhao, H. and Zhao, L. and Zhao, S. and Zhao, T. and Zhao, X.F. and Zhao, Y. and Zhao, Y. and Zhao, Y. and Zhao, Y. and Zheng, G. and Zheng, K. and Zheng, L. and Zheng, S. and Zheng, X.L. and Zheng, Y. and Zheng, Z.G. and Zhivotovsky, B. and Zhong, Q. and Zhou, A. and Zhou, B. and Zhou, C. and Zhou, G. and Zhou, H. and Zhou, H. and Zhou, H. and Zhou, J. and Zhou, J. and Zhou, J. and Zhou, J. and Zhou, K. and Zhou, R. and Zhou, X.J. and Zhou, Y. and Zhou, Y. and Zhou, Y. and Zhou, Z.Y. and Zhou, Z. and Zhu, B. and Zhu, C. and Zhu, G.Q. and Zhu, H. and Zhu, H. and Zhu, H. and Zhu, W.G. and Zhu, Y. and Zhu, Y. and Zhuang, H. and Zhuang, X. and Zientara-Rytter, K. and Zimmermann, C.M. and Ziviani, E. and Zoladek, T. and Zong, W.X. and Zorov, D.B. and Zorzano, A. and Zou, W. and Zou, Z. and Zou, Z. and Zuryn, S. and Zwerschke, W. and Brand-Saberi, B. and Dong, X.C. and Kenchappa, C.S. and Li, Z. and Lin, Y. and Oshima, S. and Rong, Y. and Sluimer, J.C. and Stallings, C.L. and Tong, C.K.
Autophagy 17 (1): 1-382. 8 February 2021

Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells.
Klockmeier, K. and Silva Ramos, E. and Raskó, T. and Martí Pastor, A. and Wanker, E.E.
Journal of Molecular Biology 433 (19): 167184. 17 September 2021

Bioaccumulation of therapeutic drugs by human gut bacteria.
Klünemann, M. and Andrejev, S. and Blasche, S. and Mateus, A. and Phapale, P. and Devendran, S. and Vappiani, J. and Simon, B. and Scott, T.A. and Kafkia, E. and Konstantinidis, D. and Zirngibl, K. and Mastrorilli, E. and Banzhaf, M. and Mackmull, M.T. and Hövelmann, F. and Nesme, L. and Brochado, A.R. and Maier, L. and Bock, T. and Periwal, V. and Kumar, M. and Kim, Y. and Tramontano, M. and Schultz, C. and Beck, M. and Hennig, J. and Zimmermann, M. and Sévin, D.C. and Cabreiro, F. and Savitski, M.M. and Bork, P. and Typas, A. and Patil, K.R.
Nature 597 : 533-538. 23 September 2021

The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt, D. and Perez-Hernandez, D. and Fleuter, C. and Dahlmann, M. and Zincke, F. and Smith, J. and Migotti, R. and Popp, O. and Burock, S. and Walther, W. and Dittmar, G. and Mertins, P. and Stein, U.
Oncogene 40 (34): 5286-5301. 26 August 2021

Real-time cell migration monitoring to analyze drug synergism in the scratch assay using the IncuCyte system.
Kobelt, D. and Walther, W. and Stein, U.S.
Methods in Molecular Biology 2294 : 133-142. 2021

Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M. and Mikuda, N. and Höpken, U.E. and Kärgel, E. and Uyar, B. and Tufan, A.B. and Milanovic, M. and Sun, W. and Krahn, I. and Schleich, K. and von Hoff, L. and Hinz, M. and Willenbrock, M. and Jungmann, S. and Akalin, A. and Lee, S. and Schmidt-Ullrich, R. and Schmitt, C.A. and Scheidereit, C.
EMBO Journal 40 (6): e104296. 15 March 2021

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds.
Kowalczyk, I. and Lee, C. and Schuster, E. and Hoeren, J. and Trivigno, V. and Riedel, L. and Görne, J. and Wallingford, J.B. and Hammes, A. and Feistel, K.
Development 148 (2): dev195008. 26 January 2021

Fluorine ((19)F) MRI for assessing inflammatory cells in the kidney: experimental protocol.
Ku, M.C. and Schreiber, A. and Delgado, P.R. and Boehm-Sturm, P. and Kettritz, R. and Niendorf, T. and Pohlmann, A. and Waiczies, S.
Methods in Molecular Biology 2216 : 495-507. 2021

An oscillatory network controlling self-renewal of skeletal muscle stem cells.
Lahmann, I. and Zhang, Y. and Baum, K. and Wolf, J. and Birchmeier, C.
Experimental Cell Research 409 (2): 112933. 15 December 2021

Principles of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancers.
Lange, J.T. and Chen, C.Y. and Pichugin, Y. and Xie, L. and Tang, J. and Hung, K.L. and Yost, K.E. and Shi, Q. and Erb, M.L. and Rajkumar, U. and Wu, S. and Swanton, C. and Liu, Z. and Huang, W. and Chang, H.Y. and Bafna, V. and Henssen, A.G. and Werner, B. and Mischel, P.S.
bioRxiv : 10.1101/2021.06.11.447968. 11 June 2021

Generation of human brain organoids for mitochondrial disease modeling.
Le, S. and Petersilie, L. and Inak, G. and Menacho-Pando, C. and Kafitz, K.W. and Rybak-Wolf, A. and Rajewsky, N. and Rose, C.R. and Prigione, A.
Journal of Visualized Experiments (172): e62756. 21 June 2021

Virus-induced senescence is driver and therapeutic target in COVID-19.
Lee, S. and Yu, Y. and Trimpert, J. and Benthani, F. and Mairhofer, M. and Richter-Pechanska, P. and Wyler, E. and Belenki, D. and Kaltenbrunner, S. and Pammer, M. and Kausche, L. and Firsching, T.C. and Dietert, K. and Schotsaert, M. and Martínez-Romero, C. and Singh, G. and Kunz, S. and Niemeyer, D. and Ghanem, R. and Salzer, H.J.F. and Paar, C. and Mülleder, M. and Uccellini, M. and Michaelis, E.G. and Khan, A. and Lau, A. and Schönlein, M. and Habringer, A. and Tomasits, J. and Adler, J.M. and Kimeswenger, S. and Gruber, A.D. and Hoetzenecker, W. and Steinkellner, H. and Purfuerst, B. and Motz, R. and Di Pierro, F. and Lamprecht, B. and Osterrieder, N. and Landthaler, M. and Drosten, C. and García-Sastre, A. and Langer, R. and Ralser, M. and Eils, R. and Reimann, M. and Fan, D.N.Y. and Schmitt, C.A.
Nature 599 : 283-289. 11 November 2021

Technologies for profiling the impact of genomic variants on transcription factor binding.
Leiz, J. and Rutkiewicz, M. and Birchmeier, C. and Heinemann, U. and Schmidt-Ott, K.M.
Medizinische Genetik 33 (2): 147-155. 14 August 2021

The somatosensory world of the African naked mole-rat.
Lewin, G.R. and Smith, E.S.J. and Reznick, J. and Debus, K.Y. and Barker, A.J. and Park, T.J.
Advances in Experimental Medicine and Biology 1319 (1319): 197-220. 24 August 2021

Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice.
Li, C. and Goncalves, K.A. and Raskó, T. and Pande, A. and Gil, S. and Liu, Z. and Izsvák, Z. and Papayannopoulou, T. and Davis, J.C. and Kiem, H.P. and Lieber, A.
Blood Advances 5 (5): 1239-1249. 9 March 2021

Coupling proteomics and metabolomics for the unsupervised identification of protein-metabolite interactions in Chaetomium thermophilum.
Li, Y. and Kuhn, M. and Zukowska-Kasprzyk, J. and Hennrich, M.L. and Kastritis, P.L. and O'Reilly, F.J. and Phapale, P. and Beck, M. and Gavin, A.C. and Bork, P.
PLoS ONE 16 (7): e0254429. 9 July 2021

Systematic identification of MACC1-driven metabolic networks in colorectal cancer.
Lisec, J. and Kobelt, D. and Walther, W. and Mokrizkij, M. and Grötzinger, C. and Jaeger, C. and Baum, K. and Simon, M. and Wolf, J. and Beindorff, N. and Brenner, W. and Stein, U.
Cancers 13 (5): 978. 26 February 2021

Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily.
Liu, J. and Tassinari, M. and Souza, D.P. and Naskar, S. and Noel, J.K. and Bohuszewicz, O. and Buck, M. and Williams, T.A. and Baum, B. and Low, H.H.
Cell 184 (14): 3660-3673. 8 July 2021

Microglia sense neuronal activity via GABA in the early postnatal hippocampus.
Logiacco, F. and Xia, P. and Georgiev, S.V. and Franconi, C. and Chang, Y.J. and Ugursu, B. and Sporbert, A. and Kühn, R. and Kettenmann, H. and Semtner, M.
Cell Reports 37 (13): 110128. 28 December 2021

Genetic background but not intestinal microbiota after co-housing determines hyperoxaluria-related nephrocalcinosis in common inbred mouse strains.
Ma, Q. and Grigorescu, M. and Schreiber, A. and Kettritz, R. and Lindenmeyer, M. and Anders, H.J. and Steiger, S.
Frontiers in Immunology 12 : 673423. 21 April 2021

A simple spatial-independent associative and reversal learning task in mice.
Magara, F. and Boury-Jamot, B. and Hörnberg, H.
Bio-protocol 11 (15): e4108. 5 August 2021

3D MRI of explanted sheep hearts with submillimeter isotropic spatial resolution: comparison between diffusion tensor and structure tensor imaging.
Magat, J. and Ozenne, V. and Cedilnik, N. and Naulin, J. and Haliot, K. and Sermesant, M. and Gilbert, S.H. and Trew, M. and Haissaguerre, M. and Quesson, B. and Bernus, O.
Magnetic Resonance Materials in Physics Biology and Medicine 34 (5): 741-755. October 2021

Age-related decline in murine heart and skeletal muscle performance is attenuated by reduced Ahnak1 expression.
Mahmoodzadeh, S. and Koch, K. and Schriever, C. and Xu, J. and Steinecker, M. and Leber, J. and Dworatzek, E. and Purfürst, B. and Kunz, S. and Recchia, D. and Canepari, M. and Heuser, A. and Di Francescantonio, S. and Morano, I.
Journal of Cachexia Sarcopenia and Muscle 12 : 1249-1265. 14 October 2021

Unravelling the collateral damage of antibiotics on gut bacteria.
Maier, L. and Goemans, C.V. and Wirbel, J. and Kuhn, M. and Eberl, C. and Pruteanu, M. and Müller, P. and Garcia-Santamarina, S. and Cacace, E. and Zhang, B. and Gekeler, C. and Banerjee, T. and Anderson, E.E. and Milanese, A. and Löber, U. and Forslund, S.K. and Patil, K.R. and Zimmermann, M. and Stecher, B. and Zeller, G. and Bork, P. and Typas, A.
Nature 599 : 120-124. 4 November 2021

Humoral and cellular immune responses in SARS-CoV-2 mRNA-vaccinated patients with cancer.
Mairhofer, M. and Kausche, L. and Kaltenbrunner, S. and Ghanem, R. and Stegemann, M. and Klein, K. and Pammer, M. and Rauscher, I. and Salzer, H.J.F. and Doppler, S. and Habringer, A. and Paar, C. and Kimeswenger, S. and Hoetzenecker, W. and Lamprecht, B. and Lee, S. and Schmitt, C.A.
Cancer Cell 39 (9): 1171-1172. 13 September 2021

GAS1 is required for Notch-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.
Marczenke, M. and Sunaga, D. and Popp, O. and Althaus, I.W. and Sauer, S. and Mertins, P. and Christ, A. and Allen, B.L. and Willnow, T.E.
Development 148 (21): dev200080. 11 November 2021

Disrupting the CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Marino, S.F. and Jerke, U. and Rolle, S. and Daumke, O. and Kettritz, R.
bioRxiv : 2021.05.17.444335. 17 May 2021

The rise of proteome-wide biophysics.
Mateus, A. and Savitski, M.M. and Piazza, I.
Molecular Systems Biology 17 (7): e10442. July 2021

Identification of disease-relevant modulators of the SHH pathway in the developing brain.
Mecklenburg, N. and Kowalczyk, I. and Witte, F. and Görne, J. and Laier, A. and Mamo, T.M. and Gonschior, H. and Lehmann, M. and Richter, M. and Sporbert, A. and Purfürst, B. and Hübner, N. and Hammes, A.
Development 148 (17): dev199307. September 2021

Lymphocyte access to lymphoma is impaired by high endothelial venule regression.
Menzel, L. and Zschummel, M. and Crowley, T. and Franke, V. and Grau, M. and Ulbricht, C. and Hauser, A. and Siffrin, V. and Bajénoff, M. and Acton, S.E. and Akalin, A. and Lenz, G. and Willimsky, G. and Höpken, U.E. and Rehm, A.
Cell Reports 37 (4): 109878. 26 October 2021

Phenylalanine-hydroxylase contributes to serotonin synthesis in mice.
Mordhorst, A. and Dhandapani, P. and Matthes, S. and Mosienko, V. and Rothe, M. and Todiras, M. and Self, J. and Schunck, W.H. and Schütz, A. and Bader, M. and Alenina, N.
FASEB Journal 35 (6): e21648. June 2021

Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca, P. and Jäntti, N.Z. and Godbole, R. and Sommer, C. and Jacquemet, G. and Al-Akhrass, H. and Conway, J.R.W. and Kronqvist, P. and Kallionpää, R.E. and Oliveira-Ferrer, L. and Cervero, P. and Linder, S. and Aepfelbacher, M. and Zauber, H. and Rae, J. and Parton, R.G. and Disanza, A. and Scita, G. and Mayor, S. and Selbach, M. and Veltel, S. and Ivaska, J.
Nature Cell Biology 23 (10): 1073-1084. October 2021

Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Nikolay, R. and Hilal, T. and Schmidt, S. and Qin, B. and Schwefel, D. and Vieira-Vieira, C.H. and Mielke, T. and Bürger, J. and Loerke, J. and Amikura, K. and Flügel, T. and Ueda, T. and Selbach, M. and Deuerling, E. and Spahn, C.M.T.
Molecular Cell 81 (6): 1200-1215. 18 March 2021

Lysine acetylation regulates the interaction between proteins and membranes.
Okada, A.K. and Teranishi, K. and Ambroso, M.R. and Isas, J.M. and Vazquez-Sarandeses, E. and Lee, J.Y. and Melo, A.A. and Pandey, P. and Merken, D. and Berndt, L. and Lammers, M. and Daumke, O. and Chang, K. and Haworth, I.S. and Langen, R.
Nature Communications 12 (1): 6466. 9 November 2021

GUNC: detection of chimerism and contamination in prokaryotic genomes.
Orakov, A. and Fullam, A. and Coelho, L.P. and Khedkar, S. and Szklarczyk, D. and Mende, D.R. and Schmidt, T.S.B. and Bork, P.
Genome Biology 22 (1): 178. 13 June 2021

Activation of tripartite motif containing 63 expression by transcription factor EB and transcription factor binding to immunoglobulin heavy chain enhancer 3 is regulated by protein kinase D and class IIa histone deacetylases.
Pablo Tortola, C. and Fielitz, B. and Li, Y. and Rüdebusch, J. and Luft, F.C. and Fielitz, J.
Frontiers in Physiology 11 : 550506. 13 January 2021

Effective oncoleaking treatment of pancreatic cancer by claudin-targeted suicide gene therapy with Clostridium perfringens enterotoxin (CPE).
Pahle, J. and Kobelt, D. and Aumann, J. and Behrens, D. and Daberkow, O. and Mokritzkij, M. and Piontek, J. and Stein, U. and Walther, W.
Cancers 13 (17): 4393. 1 September 2021

Uncharted biosynthetic potential of the ocean microbiome.
Paoli, L. and Ruscheweyh, H.J. and Forneris, C.C. and Kautsar, S. and Clayssen, Q. and Salazar, G. and Milanese, A. and Gehrig, D. and Larralde, M. and Carroll, L.M. and Sánchez, P. and Zayed, A.A. and Cronin, D.R. and Acinas, S.G. and Bork, P. and Bowler, C. and Delmont, T.O. and Sullivan, M.B. and Wincker, P. and Zeller, G. and Robinson, S.L. and Piel, J. and Sunagawa, S.
bioRxiv : 2021.03.24.436479. 24 March 2021

African naked mole-rats demonstrate extreme tolerance to hypoxia and hypercapnia.
Park, T.J. and Smith, E.S.J. and Reznick, J. and Bennett, N.C. and Applegate, Daniel T and Larson, J. and Lewin, G.R.
Advances in Experimental Medicine and Biology 1319 (1319): 255-269. 24 August 2021

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
Pekayvaz, K. and Leunig, A. and Kaiser, R. and Brambs, S. and Joppich, M. and Janjic, A. and Popp, O. and Polewka, V. and Wange, L.E. and Gold, C. and Kirchner, M. and Muenchhoff, M. and Hellmuth, J.C. and Scherer, C. and Eser, T. and Deák, F. and Kuhl, N. and Linder, A. and Saar, K. and Tomas, L. and Schulz, C. and Enard, W. and Kroidl, I. and Geldmacher, C. and von Bergwelt-Baildon, M. and Keppler, O.T. and Zimmer, R. and Mertins, P. and Hubner, N. and Hölscher, M. and Massberg, S. and Stark, K. and Nicolai, L.
bioRxiv : 2021.02.03.429351. 3 February 2021

Community-wide experimental evaluation of the PROSS stability-design method.
Peleg, Y. and Vincentelli, R. and Collins, B.M. and Chen, K.E. and Livingstone, E.K. and Weeratunga, S. and Leneva, N. and Guo, Q. and Remans, K. and Perez, K. and Bjerga, G.E.K. and Larsen, Ø. and Vaněk, O. and Skořepa, O. and Jacquemin, S. and Poterszman, A. and Kjaer, S. and Christodoulou, E. and Albeck, S. and Dym, O. and Ainbinder, E. and Unger, T. and Schuetz, A. and Matthes, S. and Bader, M. and de Marco, A. and Storici, P. and Semrau, M.S. and Stolt-Bergner, P. and Aigner, C. and Suppmann, S. and Goldenzweig, A. and Fleishman, S.J.
Journal of Molecular Biology 433 (13): 166964. 25 June 2021

Astrocytes and oligodendrocytes in the thalamus jointly maintain synaptic activity by supplying metabolites.
Philippot, C. and Griemsmann, S. and Jabs, R. and Seifert, G. and Kettenmann, H. and Steinhäuser, C.
Cell Reports 34 (3): 108642. 19 January 2021

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains.
Pluska, L. and Jarosch, E. and Zauber, H. and Kniss, A. and Waltho, A. and Bagola, K. and von Delbrück, M. and Löhr, F. and Schulman, B.A. and Selbach, M. and Dötsch, V. and Sommer, T.
EMBO Journal 40 (6): e106094. 15 March 2021

Pentafluorosulfanyl (SF(5)) as a superior (19)F magnetic resonance reporter group: signal detection and biological activity of teriflunomide derivatives.
Prinz, C. and Starke, L. and Ramspoth, T.F. and Kerkering, J. and Martos Riaño, V. and Paul, J. and Neuenschwander, M. and Oder, A. and Radetzki, S. and Adelhoefer, S. and Ramos Delgado, P. and Aravina, M. and Millward, J.M. and Fillmer, A. and Paul, F. and Siffrin, V. and von Kries, J.P. and Niendorf, T. and Nazaré, M. and Waiczies, S.
ACS Sensors 6 (11): 3948–3956. 26 November 2021

YAP and β-catenin cooperate to drive oncogenesis in basal breast cancer.
Quinn, H.M. and Vogel, R. and Popp, O. and Mertins, P. and Lan, L. and Messerschmidt, C. and Landshammer, A. and Lisek, K. and Château-Joubert, S. and Marangoni, E. and Koren, E. and Fuchs, Y. and Birchmeier, W.
Cancer Research 81 (8): 2116-2127. April 2021

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.
Ramberger, E. and Sapozhnikova, V. and Kowenz-Leutz, E. and Zimmermann, K. and Nicot, N. and Nazarov, P.V. and Perez-Hernandez, D. and Reimer, U. and Mertins, P. and Dittmar, G. and Leutz, A.
iScience 24 (6): 102686. 25 June 2021

A universal peptide matrix interactomics approach to disclose motif dependent protein binding.
Ramberger, E. and Suarez-Artiles, L. and Perez-Hernandez, D. and Haji, M. and Popp, O. and Reimer, U. and Leutz, A. and Dittmar, G. and Mertins, P.
Molecular & Cellular Proteomics 20 : 100135. 13 August 2021

PiggyBac transposable element-derived 1 controls neuronal progenitor identity, stress sensing and mammal-specific paraspeckles.
Raskó, T. and Pande, A. and Radscheit, K. and Zink, A. and Singh, M. and Sommer, C. and Wachtl, G. and Kolacsek, O. and Inak, G. and Szvetnik, A. and Petrakis, S. and Bunse, M. and Bansal, V. and Selbach, M. and Orbán, T. and Prigione, A. and Hurst, L.D. and Izsvák, Z.
bioRxiv : 2021.05.19.444448. 19 May 2021

Early days of tenascin-R research: two approaches discovered and shed light on tenascin-R.
Rathjen, F.G. and Hodge, R.
Frontiers in Immunology 11 : 612482. 8 January 2021

Expanding the phenotype of NUP85 mutations beyond nephrotic syndrome to primary autosomal recessive microcephaly and Seckel syndrome spectrum disorders.
Ravindran, E. and Jühlen, R. and Vieira-Vieira, C.H. and Ha, T. and Salzberg, Y. and Fichtman, B. and Luise-Becker, L. and Martins, N. and Picker-Minh, S. and Bessa, P. and Arts, P. and Jackson, M.R. and Taranath, A. and Kamien, B. and Barnett, C. and Li, N. and Tarabykin, V. and Stoltenburg-Didinger, G. and Harel, A. and Selbach, M. and Dickmanns, A. and Fahrenkrog, B. and Hu, H. and Scott, H. and Kaindl, A.M.
Human Molecular Genetics 30 (22): 2068-2081. 15 November 2021

Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma.
Regina, C. and Hamed, E. and Andrieux, G. and Angenendt, S. and Schneider, M. and Ku, M. and Follo, M. and Wachtel, M. and Ke, E. and Kikuchi, K. and Henssen, A.G. and Schäfer, B.W. and Boerries, M. and Wagers, A.J. and Keller, C. and Hettmer, S.
Life Science Alliance 4 (9): e202001002. September 2021

A sweet story of metabolic innovation in the naked mole-rat.
Reznick, J. and Park, T.J. and Lewin, G.R.
Advances in Experimental Medicine and Biology 1319 (1319): 271-286. 24 August 2021

Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma.
Roeschert, I. and Poon, E. and Henssen, A.G. and Dorado Garcia, H. and Gatti, M. and Giansanti, C. and Jamin, Y. and Ade, C.P. and Gallant, P. and Schülein-Völk, C. and Beli, P. and Richards, M. and Rosenfeldt, M. and Altmeyer, M. and Anderson, J. and Eggert, A. and Dobbelstein, M. and Bayliss, R. and Chesler, L. and Büchel, G. and Eilers, M.
Nature Cancer 2 (3): 312-326. March 2021

A versatile sub-nanomolar fluorescent ligand enables NanoBRET binding studies and single-molecule microscopy at the histamine H(3) receptor.
Rosier, N. and Grätz, L. and Schihada, H. and Möller, J. and Işbilir, A. and Humphrys, L.J. and Nagl, M. and Seibel, U. and Lohse, M.J. and Pockes, S.
Journal of Medicinal Chemistry 64 (15): 11695-11708. 12 August 2021

Compendium of 530 metagenome-assembled bacterial and archaeal genomes from the polar Arctic Ocean.
Royo-Llonch, M. and Sánchez, P. and Ruiz-González, C. and Salazar, G. and Pedrós-Alió, C. and Sebastián, M. and Labadie, K. and Paoli, L. and M. Ibarbalz, F. and Zinger, L. and Churcheward, B. and Chaffron, S. and Eveillard, D. and Karsenti, E. and Sunagawa, S. and Wincker, P. and Karp-Boss, L. and Bowler, C. and Acinas, S.G.
Nature Microbiology 6 (12): 1561-1574. December 2021

Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7-related osteopetrosis.
Rössler, U. and Hennig, A.F. and Stelzer, N. and Bose, S. and Kopp, J. and Søe, K. and Cyganek, L. and Zifarelli, G. and Ali, S. and von der Hagen, M. and Strässler, E.T. and Hahn, G. and Pusch, M. and Stauber, T. and Izsvák, Z. and Gossen, M. and Stachelscheid, H. and Kornak, U.
Journal of Bone and Mineral Research 36 (8): 1621-1635. August 2021

Reduction of cortical parvalbumin expressing GABAergic interneurons in a rodent hyperoxia model of preterm birth brain injury with deficits in social behavior and cognition.
Scheuer, T. and Auf dem Brinke, E. and Grosser, S. and Wolf, S.A. and Mattei, D. and Sharkovska, Y. and Barthel, P.C. and Endesfelder, S. and Friedrich, V. and Bührer, C. and Vida, I. and Schmitz, T.
Development 148 (20): dev.198390. October 2021

Bioluminescence in G protein-coupled receptors drug screening using nanoluciferase and halo-tag technology.
Schihada, H. and Nemec, K. and Lohse, M.J. and Maiellaro, I.
Methods in Molecular Biology 2268 : 137-147. 2021

Small, seeding-competent huntingtin fibrils are prominent aggregate species in brains of zQ175 Huntington's disease knock-in mice.
Schindler, F. and Praedel, N. and Neuendorf, N. and Kunz, S. and Schnoegl, S. and Mason, M.A. and Taxy, B.A. and Bates, G.P. and Khoshnan, A. and Priller, J. and Grimm, J. and Maier, M. and Boeddrich, A. and Wanker, E.E.
Frontiers in Neuroscience 15 : 682172. 22 June 2021

Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Schmelz, K. and Toedling, J. and Huska, M. and Cwikla, M.C. and Kruetzfeldt, L.M. and Proba, J. and Ambros, P.F. and Ambros, I.M. and Boral, S. and Lodrini, M. and Chen, C.Y. and Burkert, M. and Guergen, D. and Szymansky, A. and Astrahantseff, K. and Kuenkele, A. and Haase, K. and Fischer, M. and Deubzer, H.E. and Hertwig, F. and Hundsdoerfer, P. and Henssen, A.G. and Schwarz, R.F. and Schulte, J.H. and Eggert, A.
Nature Communications 12 (1): 6804. 23 November 2021

Drivers and determinants of strain dynamics following faecal microbiota transplantation.
Schmidt, T.S.B. and Li, S.S. and Maistrenko, O.M. and Akanni, W. and Coelho, L.P. and Dolai, S. and Fullam, A. and Glazek, A.M. and Hercog, R. and Herrema, H. and Jung, F. and Kandels, S. and Orakov, A. and Van Rossum, T. and Benes, V. and Borody, T.J. and de Vos, W.M. and Ponsioen, C.Y. and Nieuwdorp, M. and Bork, P.
bioRxiv : 2021.09.30.462010. 30 September 2021

On the adhesion-velocity relation and length adaptation of motile cells on stepped fibronectin lanes.
Schreiber, C. and Amiri, B. and Heyn, J.C.J. and Rädler, J.O. and Falcke, M.
Proceedings of the National Academy of Sciences of the United States of America 118 (4): e2009959118. 26 January 2021

On the relation between input and output distributions of scRNA-seq experiments.
Schwabe, D. and Falcke, M.
bioRxiv : 2021.10.08.463628v1. 9 October 2021

CellFIE: CRISPR- and cell fusion-based two-hybrid interaction mapping of endogenous proteins.
Secker, C. and Kostova, S. and Niederlechner, H. and Beetz, S. and Wendland, I. and Liebich, M.J. and Polzer, O. and Groh, M. and Schnoegl, S. and Trepte, P. and Wanker, E.E.
Journal of Molecular Biology 433 (24): 167305. 3 December 2021

Structural and functional characterization of allatostatin receptor type-C of Thaumetopoea pityocampa, a potential target for next-generation pest control agents.
Shahraki, A. and Işbilir, A. and Dogan, B. and Lohse, M.J. and Durdagi, S. and Birgul-Iyison, N.
Journal of Chemical Information and Modeling 61 (2): 715-728. 22 February 2021

Local cyclic adenosine monophosphate signalling cascades - roles and targets in chronic kidney disease.
Sholokh, A. and Klussmann, E.
Acta Physiologica 232 (1): e13641. May 2021

Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy.
Sommariva, E. and Stadiotti, I. and Casella, M. and Catto, V. and Dello Russo, A. and Carbucicchio, C. and Arnaboldi, L. and De Metrio, S. and Milano, G. and Scopece, A. and Casaburo, M. and Andreini, D. and Mushtaq, S. and Conte, E. and Chiesa, M. and Birchmeier, W. and Cogliati, E. and Paolin, A. and König, E. and Meraviglia, V. and De Musso, M. and Volani, C. and Cattelan, G. and Rauhe, W. and Turnu, L. and Porro, B. and Pedrazzini, M. and Camera, M. and Corsini, A. and Tondo, C. and Rossini, A. and Pompilio, G.
EMBO Molecular Medicine 13 (9): e14365. 7 September 2021

Preface.
Stein, U.S.
Methods in Molecular Biology 2294 : v. 2021

Inhibiting lysine demethylase 1A improves L1CAM-specific CAR T cell therapy by unleashing antigen-independent killing via the FAS-FASL axis.
Sulejmani, O. and Grunewald, L. and Andersch, L. and Schwiebert, S. and Klaus, A. and Winkler, A. and Astrahantseff, K. and Eggert, A. and Henssen, A.G. and Schulte, J.H. and Anders, K. and Künkele, A.
Cancers 13 (21): 5489. 31 October 2021

Neuroblastoma risk assessment and treatment stratification with hybrid capture-based panel sequencing.
Szymansky, A. and Kruetzfeldt, L.M. and Heukamp, L.C. and Hertwig, F. and Theissen, J. and Deubzer, H.E. and Willing, E.M. and Menon, R. and Fuchs, S. and Thole, T. and Schulte, S. and Schmelz, K. and Künkele, A. and Lang, P. and Fuchs, J. and Eggert, A. and Eckert, C. and Fischer, M. and Henssen, A.G. and Rodriguez-Fos, E. and Schulte, J.H.
Journal of Personalized Medicine 11 (8): 691. August 2021

CD28 co-stimulus achieves superior CAR T cell effector function against solid tumors than 4-1BB co-stimulus.
Textor, A. and Grunewald, L. and Anders, K. and Klaus, A. and Schwiebert, S. and Winkler, A. and Stecklum, M. and Rolff, J. and Henssen, A.G. and Höpken, U.E. and Eggert, A. and Schulte, J.H. and Jensen, M.C. and Blankenstein, T. and Künkele, A.
Cancers 13 (5): 1050. 2 March 2021

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors.
Thibado, J. and Tano, J.Y. and Lee, J. and Salas-Estrada, L. and Provasi, D. and Strauss, A. and Lamim Ribeiro, J.M. and Xiang, G. and Broichhagen, J. and Filizola, M. and Lohse, M. and Levitz, J.
bioRxiv : 2021.02.04.429701. 6 February 2021

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors.
Thibado, J.K and Tano, J.Y. and Lee, J. and Salas-Estrada, L. and Provasi, D. and Strauss, A. and Ribeiro, J.M.L. and Xiang, G. and Broichhagen, J. and Filizola, M. and Lohse, M.J. and Levitz, J.
eLife 10 : e67027. 21 April 2021

Patient-specific modeling of diffuse large B-cell lymphoma.
Thobe, K. and Konrath, F. and Chapuy, B. and Wolf, J.
Biomedicines 9 (11): 1655. 10 November 2021

Cl(-) channels and Cl(-)/H(+) exchangers.
Ullrich, F. and Jentsch, T.J.
In: Encyclopedia of Molecular Pharmacology : Third Edition. Springer, Cham, 470-477. ISBN 978-3-030-57400-0 2021

A previously undescribed highly prevalent phage identified in a Danish Enteric Virome Catalog.
Van Espen, L. and Bak, E.G. and Beller, L. and Close, L. and Deboutte, W. and Juel, H.B. and Nielsen, T. and Sinar, D. and De Coninck, L. and Frithioff-Bøjsøe, C. and Fonvig, C.E. and Jacobsen, S. and Kjærgaard, M. and Thiele, M. and Fullam, A. and Kuhn, M. and Holm, J.C. and Bork, P. and Krag, A. and Hansen, T. and Arumugam, M. and Matthijnssens, J.
mSystems 6 (5): e00382-21. 26 October 2021

Insulin mRNA is stored in RNA granules in resting beta cells.
Vasiljević, J. and Vasiljević, D. and Ganß, K. and Sönmez, A. and Wegbrod, C. and Quezada, E. and Münster, C. and Schöniger, E. and Friedland, D. and Kipke, N. and Distler, M. and Selbach, M. and Solimena, M.
bioRxiv : 2021.05.07.443159. 29 June 2021

Proteome-wide quantitative RNA interactome capture (qRIC) identifies phosphorylation sites with regulatory potential in RBM20.
Vieira-Vieira, C.H. and Dauksaite, V. and Gotthardt, M. and Selbach, M.
bioRxiv : 2021.07.12.452044. 12 July 2021

Opportunities and challenges in global quantification of RNA-protein interaction via UV cross-linking.
Vieira-Vieira, C.H. and Selbach, M.
Frontiers in Molecular Biosciences 8 : 669939. 13 May 2021

A-kinase anchoring proteins (AKAPs).
Walker-Gray, R. and Klussmann, E.
In: Encyclopedia of Molecular Pharmacology : Third Edition. Springer, Cham, 78-83. ISBN 978-3-030-57400-0 2021

Extend, don’t rebuild: Phrasing conditional graph modification as autoregressive sequence labelling.
Weber, L. and Münchmeyer, J. and Garda, S. and Leser, U.
In: 2021 Conference on Empirical Methods in Natural Language Processing, EMNLP 2021, 7-11 Nov 2021, Punta Cana, Dominican Republic. November 2021

HunFlair: an easy-to-use tool for state-of-the-art biomedical named entity recognition.
Weber, L. and Sänger, M. and Münchmeyer, J. and Habibi, M. and Leser, U. and Akbik, A.
Bioinformatics 37 (17): 2792–2794. 1 September 2021

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.
Wendisch, D. and Dietrich, O. and Mari, T. and von Stillfried, S. and Ibarra, I.L. and Mittermaier, M. and Mache, C. and Chua, R.L. and Knoll, R. and Timm, S. and Brumhard, S. and Krammer, T. and Zauber, H. and Hiller, A.L. and Pascual-Reguant, A. and Mothes, R. and Bülow, R.D. and Schulze, J. and Leipold, A.M. and Djudjaj, S. and Erhard, F. and Geffers, R. and Pott, F. and Kazmierski, J. and Radke, J. and Pergantis, P. and Baßler, K. and Conrad, C. and Aschenbrenner, A.C. and Sawitzki, B. and Landthaler, M. and Wyler, E. and Horst, D. and Hippenstiel, S. and Hocke, A. and Heppner, F.L. and Uhrig, A. and Garcia, C. and Machleidt, F. and Herold, S. and Elezkurtaj, S. and Thibeault, C. and Witzenrath, M. and Cochain, C. and Suttorp, N. and Drosten, C. and Goffinet, C. and Kurth, F. and Schultze, J.L. and Radbruch, H. and Ochs, M. and Eils, R. and Müller-Redetzky, H. and Hauser, A.E. and Luecken, M.D. and Theis, F.J. and Conrad, C. and Wolff, T. and Boor, P. and Selbach, M. and Saliba, A.E. and Sander, L.E.
Cell 184 (26): 6243-6261. 22 December 2021

Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Willnow, D. and Benary, U. and Margineanu, A. and Vignola, M.L. and Konrath, F. and Pongrac, I.M. and Karimaddini, Z. and Vigilante, A. and Wolf, J. and Spagnoli, F.M.
Nature 597 (7874): 87-91. 2 September 2021

Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolbox.
Wirbel, J. and Zych, K. and Essex, M. and Karcher, N. and Kartal, E. and Salazar, G. and Bork, P. and Sunagawa, S. and Zeller, G.
Genome Biology 22 (1): 93. 30 March 2021

Patient-derived xenografts from solid tumors (PDX) for models of metastasis.
Wulf-Goldenberg, A. and Hoffmann, J. and Becker, M. and Brzezicha, B. and Walther, W.
Methods in Molecular Biology 2294 : 43-58. 2021

Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.
Wust, P. and Stein, U. and Ghadjar, P.
International Journal of Hyperthermia 38 (1): 715-731. 28 April 2021

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Wyler, E. and Mösbauer, K. and Franke, V. and Diag, A. and Gottula, L.T. and Arsiè, R. and Klironomos, F. and Koppstein, D. and Hönzke, K. and Ayoub, S. and Buccitelli, C. and Hoffmann, K. and Richter, A. and Legnini, I. and Ivanov, A. and Mari, T. and Del Giudice, S. and Papies, J. and Praktiknjo, S. and Meyer, T.F. and Müller, M.A. and Niemeyer, D. and Hocke, A. and Selbach, M. and Akalin, A. and Rajewsky, N. and Drosten, C. and Landthaler, M.
iScience 24 (3): 102151. 19 March 2021

Histamine triggers microglial responses indirectly via astrocytes and purinergic signaling.
Xia, P. and Logiacco, F. and Huang, Y. and Kettenmann, H. and Semtner, M.
Glia 69 (9): 2291-2304. September 2021

Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells.
Zhang, Y. and Lahmann, I. and Baum, K. and Shimojo, H. and Mourikis, P. and Wolf, J. and Kageyama, R. and Birchmeier, C.
Nature Communications 12 (1): 1318. 26 February 2021

A simple pressure-assisted method for MicroED specimen preparation.
Zhao, J. and Xu, H. and Lebrette, H. and Carroni, M. and Taberman, H. and Högbom, M. and Zou, X.
Nature Communications 12 (1): 5036. 19 August 2021

Generation of human iPSC-derived neural progenitor cells (NPCs) as drug discovery model for neurological and mitochondrial disorders.
Zink, A. and Lisowski, P. and Prigione, A.
Bio-protocol 11 (5): e3939. 5 March 2021

An introduction to advanced targeted acquisition methods.
van Bentum, M. and Selbach, M.
Molecular & Cellular Proteomics 20 : 100165. 18 October 2021

This list was generated on Sun May 26 02:19:01 2024 CEST.
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