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MDC Paper AND Times Cited is 496 or more

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1. STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets.
Szklarczyk, D. and Gable, A.L. and Lyon, D. and Junge, A. and Wyder, S. and Huerta-Cepas, J. and Simonovic, M. and Doncheva, N.T. and Morris, J.H. and Bork, P. and Jensen, L.J. and von Mering, C.
Nucleic Acids Research 47 (D1): D607-D613. 8 January 2019
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2. Circular RNAs are a large class of animal RNAs with regulatory potency.
Memczak, S. and Jens, M. and Elefsinioti, A. and Torti, F. and Krueger, J. and Rybak, A. and Maier, L. and Mackowiak, S.D. and Gregersen, L.H. and Munschauer, M. and Loewer, A. and Ziebold, U. and Landthaler, M. and Kocks, C. and le Noble, F. and Rajewsky, N.
Nature 495 (7441): 333-338. 21 March 2013
3. Enterotypes of the human gut microbiome.
Arumugam, M. and Raes, J. and Pelletier, E. and Le Paslier, D. and Yamada, T. and Mende, D.R. and Fernandes, G.R. and Tap, J. and Bruls, T. and Batto, J.M. and Bertalan, M. and Borruel, N. and Casellas, F. and Fernandez, L. and Gautier, L. and Hansen, T. and Hattori, M. and Hayashi, T. and Kleerebezem, M. and Kurokawa, K. and Leclerc, M. and Levenez, F. and Manichanh, C. and Nielsen, H.B. and Nielsen, T. and Pons, N. and Poulain, J. and Qin, J. and Sicheritz-Ponten, T. and Tims, S. and Torrents, D. and Ugarte, E. and Zoetendal, E.G. and Wang, J. and Guarner, F. and Pedersen, O. and de Vos, W.M. and Brunak, S. and Dore, J. and Weissenbach, J. and Ehrlich, S.D. and Bork, P.
Nature 473 (7346): 174-180. 12 May 2011
4. The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible.
Szklarczyk, D. and Morris, J.H. and Cook, H. and Kuhn, M. and Wyder, S. and Simonovic, M. and Santos, A. and Doncheva, N.T. and Roth, A. and Bork, P. and Jensen, L.J. and von Mering, C.
Nucleic Acids Research 45 (D1): D362-D368. 4 January 2017
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5. Global quantification of mammalian gene expression control.
Schwanhaeusser, B. and Busse, D. and Li, N. and Dittmar, G. and Schuchhardt, J. and Wolf, J. and Chen, W. and Selbach, M.
Nature 473 (7347): 337-342. 19 May 2011
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6. Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees.
Letunic, I. and Bork, P.
Nucleic Acids Research 44 (W1): W242-W245. 8 July 2016
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7. SMART, a simple modular architecture research tool: Identification of signaling domains.
Schultz, J. and Milpetz, F. and Bork, P. and Ponting, C.P.
Proceedings of the National Academy of Sciences of the United States of America 95 (11): 5857-5864. 26 May 1998
8. Widespread changes in protein synthesis induced by microRNAs.
Selbach, M. and Schwanhaeusser, B. and Thierfelder, N. and Fang, Z. and Khanin, R. and Rajewsky, N.
Nature 455 (7209): 58-63. 4 September 2008
9. Functional interaction of beta-catenin with the transcription factor LEF-1.
Behrens, J. and von Kries, J.P. and Kuehl, M. and Bruhn, L. and Wedlich, D. and Grosschedl, R. and Birchmeier, W.
Nature 382 (6592): 638-642. 15 August 1996
10. Microglia: active sensor and versatile effector cells in the normal and pathologic brain.
Hanisch, U.K. and Kettenmann, H.
Nature Neuroscience 10 (11): 1387-1394. November 2007
11. Physiology of microglia.
Kettenmann, H. and Hanisch, U.K. and Noda, M. and Verkhratsky, A.
Physiological Reviews 91 (2): 461-553. April 2011
12. Met, metastasis, motility and more.
Birchmeier, C. and Birchmeier, W. and Gherardi, E. and Vande Woude, G.F.
Nature Reviews Molecular Cell Biology 4 (12): 915-925. December 2003
13. Human non-synonymous SNPs: server and survey.
Ramensky, V. and Bork, P. and Sunyaev, S.
Nucleic Acids Research 30 (17): 3894-3900. 1 September 2002
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14. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.
Foerster, R. and Schubel, A. and Breitfeld, D. and Kremmer, E. and Renner-Mueller, I. and Wolf, E. and Lipp, M.
Cell 99 (1): 23-33. 1 October 1999
15. STRING 8--a global view on proteins and their functional interactions in 630 organisms.
Jensen, L.J. and Kuhn, M. and Stark, M. and Chaffron, S. and Creevey, C. and Muller, J. and Doerks, T. and Julien, P. and Roth, A. and Simonovic, M. and Bork, P. and von Mering, C.
Nucleic Acids Research 37 (Database Issue): D412-D416. January 2009
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16. circRNA biogenesis competes with pre-mRNA splicing.
Ashwal-Fluss, R. and Meyer, M. and Pamudurti, N.R. and Ivanov, A. and Bartok, O. and Hanan, M. and Evantal, N. and Memczak, S. and Rajewsky, N. and Kadener, S.
Molecular Cell 56 (1): 55-66. 2 October 2014
17. A human protein-protein interaction network: a resource for annotating the proteome.
Stelzl, U. and Worm, U. and Lalowski, M. and Haenig, C. and Brembeck, F.H. and Goehler, H. and Stroedicke, M. and Zenkner, M. and Schoenherr, A. and Koeppen, S. and Timm, J. and Mintzlaff, S. and Abraham, C. and Bock, N. and Kietzmann, S. and Goedde, A. and Toksoez, E. and Droege, A. and Krobitsch, S. and Korn, B. and Birchmeier, W. and Lehrach, H. and Wanker, E.E.
Cell 122 (6): 957-968. 23 September 2005
18. PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments.
Suyama, M. and Torrents, D. and Bork, P.
Nucleic Acids Research 34 (Web Server Issue): W609-W612. 1 July 2006
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19. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades.
Friedlaender, M.R. and Mackowiak, S.D. and Li, N. and Chen, W. and Rajewsky, N.
Nucleic Acids Research 40 (1): 37-52. 1 January 2012
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20. Hyperthermia in combined treatment of cancer.
Wust, P. and Hildebrandt, B. and Sreenivasa, G. and Rau, B. and Gellermann, J. and Riess, H. and Felix, R. and Schlag, P.M.
Lancet Oncology 3 (8): 487-497. August 2002
21. Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed.
Rybak-Wolf, A. and Stottmeister, C. and Glažar, P. and Jens, M. and Pino, N. and Giusti, S. and Hanan, M. and Behm, M. and Bartok, O. and Ashwal-Fluss, R. and Herzog, M. and Schreyer, L. and Papavasileiou, P. and Ivanov, A. and Öhman, M. and Refojo, D. and Kadener, S. and Rajewsky, N.
Molecular Cell 58 (5): 870-885. 4 June 2015
22. Microglia as a source and target of cytokines.
Hanisch, U.K.
Glia 40 (2): 140-155. November 2002
23. STRING: a database of predicted functional associations between proteins.
von Mering, C. and Huynen, M. and Jaeggi, D. and Schmidt, S. and Bork, P. and Snel, B.
Nucleic Acids Research 31 (1): 258-261. 1 January 2003
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24. CNS synaptogenesis promoted by glia-derived cholesterol.
Mauch, D.H. and Naegler, K. and Schumacher, S. and Goeritz, C. and Mueller, E.C. and Otto, A. and Pfrieger, F.W.
Science 294 (5545): 1354-1357. 9 November 2001
25. Wnt signalling and its impact on development and cancer.
Klaus, A. and Birchmeier, W.
Nature Reviews Cancer 8 (5): 387-398. May 2008
26. The evolution of gene regulation by transcription factors and microRNAs.
Chen, K. and Rajewsky, N.
Nature Reviews Genetics 8 (2): 93-103. February 2007
27. eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences.
Huerta-Cepas, J. and Szklarczyk, D. and Forslund, K. and Cook, H. and Heller, D. and Walter, M.C. and Rattei, T. and Mende, D.R. and Sunagawa, S. and Kuhn, M. and Jensen, L.J. and von Mering, C. and Bork, P.
Nucleic Acids Research 44 (D1): D286-D293. 4 January 2016
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28. Induction of tumors in mice by genomic hypomethylation.
Gaudet, F. and Hodgson, J.G. and Eden, A. and Jackson-Grusby, L. and Dausman, J. and Gray, J.W. and Leonhardt, H. and Jaenisch, R.
Science 300 (5618): 489-492. 18 April 2003
29. Structure and function of the global ocean microbiome.
Sunagawa, S. and Coelho, L.P. and Chaffron, S. and Kultima, J.R. and Labadie, K. and Salazar, G. and Djahanschiri, B. and Zeller, G. and Mende, D.R. and Alberti, A. and Cornejo-Castillo, F.M. and Costea, P.I. and Cruaud, C. and d'Ovidio, F. and Engelen, S. and Ferrera, I. and Gasol, J.M. and Guidi, L. and Hildebrand, F. and Kokoszka, F. and Lepoivre, C. and Lima-Mendez, G. and Poulain, J. and Poulos, B.T. and Royo-Llonch, M. and Sarmento, H. and Vieira-Silva, S. and Dimier, C. and Picheral, M. and Searson, S. and Kandels-Lewis, S. and Bowler, C. and de Vargas, C. and Gorsky, G. and Grimsley, N. and Hingamp, P. and Iudicone, D. and Jaillon, O. and Not, F. and Ogata, H. and Pesant, S. and Speich, S. and Stemmann, L. and Sullivan, M.B. and Weissenbach, J. and Wincker, P. and Karsenti, E. and Raes, J. and Acinas, S.G. and Bork, P.
Science 348 (6237): 1261359. 22 May 2015
30. Toward automatic reconstruction of a highly resolved tree of life.
Ciccarelli, F.D. and Doerks, T. and von Mehring, C. and Creevey, C.J. and Snel, B. and Bork, P.
Science 311 (5765): 1283-1287. 3 March 2006
31. Synthesis of serotonin by a second tryptophan hydroxylase isoform.
Walther, D.J. and Peter, J.U. and Bashammakh, S. and Hoertnagl, H. and Voits, M. and Fink, H. and Bader, M.
Science 299 (5603): 76-76. 3 January 2003
32. Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Behrens, J. and Jerchow, B.A. and Wuertele, M. and Grimm, J. and Asbrand, C. and Wirtz, R. and Kuehl, M. and Wedlich, D. and Birchmeier, W.
Science 280 (5363): 596-599. 24 April 1998
33. Milestones of neuronal development in the adult hippocampus.
Kempermann, G. and Jessberger, S. and Steiner, B. and Kronenberg, G.
Trends in Neurosciences 27 (8): 447-452. 1 August 2004
34. Targeting MET in cancer: rationale and progress.
Gherardi, E. and Birchmeier, W. and Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12 (2): 89-103. February 2012
35. Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud.
Bladt, F. and Riethmacher, D. and Isenmann, S. and Aguzzi, A. and Birchmeier, C.
Nature 376 (6543): 768-771. 31 August 1995
36. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.
Forslund, K. and Hildebrandt, F. and Nielsen, T. and Falony, G. and Le Chatelier, E. and Sunagawa, S. and Prifti, E. and Vieira-Silva, S. and Gudmundsdottir, V. and Pedersen, H.K. and Arumugam, M. and Kristiansen, K. and Voigt, A.Y. and Vestergaard, H. and Hercog, R. and Costea, P.I. and Kultima, J.R. and Li, J. and Jørgensen, T. and Levenez, F. and Dore, J. and Nielsen, H.B. and Brunak, S. and Raes, J. and Hansen, T. and Wang, J. and Ehrlich, S.D. and Bork, P. and Pedersen, O.
Nature 528 (7581): 262-266. 10 December 2015
37. beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
Huelsken, J. and Vogel, R. and Erdmann, B. and Cotsarelis, G. and Birchmeier, W.
Cell 105 (4): 533-545. 18 May 2001
38. EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers.
Ehrnhoefer, D.E. and Bieschke, J. and Boeddrich, A. and Herbst, M. and Masino, L. and Lurz, R. and Engemann, S. and Pastore, A. and Wanker, E.E.
Nature Structural & Molecular Biology 15 (6): 558-566. June 2008
39. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production.
Breitfeld, D. and Ohl, L. and Kremmer, E. and Ellwart, J. and Sallusto, F. and Lipp, M. and Foerster, R.
Journal of Experimental Medicine 192 (11): 1545-1551. 4 December 2000
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40. Multiple essential functions of neuregulin in development.
Meyer, D. and Birchmeier, C.
Nature 378 (6555): 386-390. 23 November 1995
41. SMART: a web-based tool for the study of genetically mobile domains.
Schultz, J. and Copley, R.R. and Doerks, T. and Ponting, C.P. and Bork, P.
Nucleic Acids Research 28 (1): 231-234. 1 January 2000
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42. Fast genome-wide functional annotation through orthology assignment by eggNOG-mapper.
Huerta-Cepas, J. and Forslund, K. and Coelho, L.P. and Szklarczyk, D. and Jensen, L.J. and von Mering, C. and Bork, P.
Molecular Biology and Evolution 34 (8): 2115-2122. 1 August 2017
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43. An integrated catalog of reference genes in the human gut microbiome.
Li, J. and Jia, H. and Cai, X. and Zhong, H. and Feng, Q. and Sunagawa, S. and Arumugam, M. and Kultima, J.R. and Prifti, E. and Nielsen, T. and Juncker, A.S. and Manichanh, C. and Chen, B. and Zhang, W. and Levenez, F. and Wang, J. and Xu, X. and Xiao, L. and Liang, S. and Zhang, D. and Zhang, Z. and Chen, W. and Zhao, H. and Al-Aama, J.Y. and Edris, S. and Yang, H. and Wang, J. and Hansen, T. and Nielsen, H.B. and Brunak, S. and Kristiansen, K. and Guarner, F. and Pedersen, O. and Dore, J. and Ehrlich, S.D. and Bork, P. and Wang, J.
Nature Biotechnology 32 (8): 834-841. August 2014
44. A chemokine-driven positive feedback loop organizes lymphoid follicles.
Ansel, K.M. and Ngo, V.N. and Hyman, P.L. and Luther, S.A. and Foerster, R. and Sedgwick, J.D. and Browning, J.L. and Lipp, M. and Cyster, J.G.
Nature 406 (6793): 309-314. 20 July 2000
45. Translation of circRNAs.
Pamudurti, N.R. and Bartok, O. and Jens, M. and Ashwal-Fluss, R. and Stottmeister, C. and Ruhe, L. and Hanan, M. and Wyler, E. and Perez-Hernandez, D. and Ramberger, E. and Shenzis, S. and Samson, M. and Dittmar, G. and Landthaler, M. and Chekulaeva, M. and Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017
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46. ERAD: the long road to destruction.
Meusser, B. and Hirsch, C. and Jarosch, E. and Sommer, T.
Nature Cell Biology 7 (8): 766-772. August 2005
47. Protein disorder prediction: Implications for structural proteomics.
Linding, R. and Jensen, L.J. and Diella, F. and Bork, P. and Gibson, T.J. and Russell, R.B.
Structure with Folding & Design 11 (11): 1453-1459. 1 November 2003
48. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen.
Foerster, R. and Mattis, A. and Kremmer, E. and Wolf, E. and Brem, G. and Lipp, M.
Cell 87 (6): 1037-1047. 13 December 1996
49. circBase: a database for circular RNAs.
Glažar, P. and Papavasileiou, P. and Rajewsky, N.
RNA 20 (11): 1666-1670. November 2014
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50. Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M. and Lee, S. and Loddenkemper, C. and Rudolph, C. and Peters, A.H. and Schlegelberger, B. and Stein, H. and Doerken, B. and Jenuwein, T. and Schmitt, C.A.
Nature 436 (7051): 660-665. 4 August 2005
51. Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness.
Birchmeier, W. and Behrens, J.
Biochimica et Biophysica Acta 1198 (1): 11-26. 27 May 1994
52. Discovering microRNAs from deep sequencing data using miRDeep.
Friedlaender, M.R. and Chen, W. and Adamidi, C. and Maaskola, J. and Einspanier, R. and Knespel, S. and Rajewsky, N.
Nature Biotechnology 26 (4): 407-415. April 2008
53. Drug target identification using side-effect similarity.
Campillos, M. and Kuhn, M. and Gavin, A.C. and Jensen, L.J. and Bork, P.
Science 321 (5886): 263-266. 11 July 2008
54. Prediction of deleterious human alleles.
Sunyaev, S.R. and Ramensky, V. and Koch, I. and Lathe, W. and Kondrashov, A.S. and Bork, P.
Human Molecular Genetics 10 (6): 591-597. 1 January 2001
55. Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.
Borsellino, G. and Kleinewietfeld, M. and Di Mitri, D. and Sternjak, A. and Diamantini, A. and Giometto, R. and Hoepner, S. and Centonze, D. and Bernardi, G. and Dell'Acqua, M.L. and Rossini, P.M. and Battistini, L. and Roetzschke, O. and Falk, K.
Blood 110 (4): 1225-1232. 15 August 2007
56. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Kleinewietfeld, M. and Manzel, A. and Titze, J. and Kvakan, H. and Yosef, N. and Linker, R.A. and Muller, D.N. and Hafler, D.A.
Nature 496 (7446): 518-522. 25 April 2013
57. Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
Lustig, B. and Jerchow, B. and Sachs, M. and Weiler, S. and Pietsch, T. and Karsten, U. and van de Wetering, M. and Clevers, H. and Schlag, P.M. and Birchmeier, W. and Behrens, J.
Molecular and Cellular Biology 22 (4): 1184-1193. 1 February 2002
58. Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome.
Varon, R. and Vissinga, C. and Platzer, M. and Cerosaletti, K.M. and Chrzanowska, K.H. and Saar, K. and Beckmann, G. and Seemanova, E. and Cooper, P.R. and Nowak, N.J. and Stumm, M. and Weemaes, C.M.R. and Gatti, R.A. and Wilson, R.K. and Digweed, M. and Rosenthal, A. and Sperling, K. and Concannon, P. and Reis, A.
Cell 93 (3): 467-476. 1 May 1998
59. Tight junctions of the blood-brain barrier: development, composition and regulation.
Wolburg, H. and Lippoldt, A.
Vascular Pharmacology 38 (6): 323-337. June 2002
60. A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy.
Schmitt, C.A. and Fridman, J.S. and Yang, M. and Lee, S. and Baranov, E. and Hoffman, R.M. and Lowe, S.W.
Cell 109 (3): 335-346. 3 May 2002
61. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz, A.G. and Munschauer, M. and Schwanhaeusser, B. and Vasile, A. and Murakawa, Y. and Schueler, M. and Youngs, N. and Penfold-Brown, D. and Drew, K. and Milek, M. and Wyler, E. and Bonneau, R. and Selbach, M. and Dieterich, C. and Landthaler, M.
Molecular Cell 46 (5): 674-690. 8 June 2012
62. Conservation of gene order: a fingerprint of proteins that physically interact.
Dandekar, T. and Snel, B. and Huynen, M. and Bork, P.
Trends in Biochemical Sciences 23 (9): 324-328. 1 September 1998
63. Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice.
Kempermann, G. and Gast, D. and Kronenberg, G. and Yamaguchi, M. and Gage, F.H.
Development 130 (2): 391-399. January 2003
64. ETE 3: reconstruction, analysis and visualization of phylogenomic data.
Huerta-Cepas, J. and Serra, F. and Bork, P.
Molecular Biology and Evolution 33 (6): 1635-1638. June 2016
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65. Extensive impact of non-antibiotic drugs on human gut bacteria.
Maier, L. and Pruteanu, M. and Kuhn, M. and Zeller, G. and Telzerow, A. and Anderson, E.E. and Brochado, A.R. and Fernandez, K.C. and Dose, H. and Mori, H. and Patil, K.R. and Bork, P. and Typas, A.
Nature 555 (7698): 623-628. 29 March 2018
66. An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D-3.
Nykjaer, A. and Dragun, D. and Walther, D. and Vorum, H. and Jacobsen, C. and Herz, J. and Melsen, F. and Christensen, E.I. and Willnow, T.E.
Cell 96 (4): 507-515. 19 February 1999
67. eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses.
Huerta-Cepas, J. and Szklarczyk, D. and Heller, D. and Hernández-Plaza, A. and Forslund, S.K. and Cook, H. and Mende, D.R. and Letunic, I. and Rattei, T. and Jensen, L.J. and von Mering, C. and Bork, P.
Nucleic Acids Research 47 (D1): D309-D314. 8 January 2019
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68. Microglia: new roles for the synaptic stripper.
Kettenmann, H. and Kirchhoff, F. and Verkhratsky, A.
Neuron 77 (1): 10-18. 9 January 2013
69. Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Chu, V.T. and Weber, T. and Wefers, B. and Wurst, W. and Sander, S. and Rajewsky, K. and Kühn, R.
Nature Biotechnology 33 (5): 543-548. May 2015
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70. EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity.
Bieschke, J. and Russ, J. and Friedrich, R.P. and Ehrnhoefer, D.E. and Wobst, H. and Neugebauer, K. and Wanker, E.E.
Proceedings of the National Academy of Sciences of the United States of America 107 (17): 7710-7715. 27 April 2010
71. The role of microglia and macrophages in glioma maintenance and progression.
Hambardzumyan, D. and Gutmann, D.H. and Kettenmann, H.
Nature Neuroscience 19 (1): 20-27. January 2016
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72. Electron beam computed tomography in the evaluation of cardiac calcifications in chronic dialysis patients.
Braun, J. and Oldendorf, M. and Moshage, W. and Heidler, R. and Zeitler, E. and Luft, F.C.
American Journal of Kidney Diseases 27 (3): 394-401. 1 January 1996
73. Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.
You, X. and Vlatkovic, I. and Babic, A. and Will, T. and Epstein, I. and Tushev, G. and Akbalik, G. and Wang, M. and Glock, C. and Quedenau, C. and Wang, X. and Hou, J. and Liu, H. and Sun, W. and Sambandan, S. and Chen, T. and Schuman, E.M. and Chen, W.
Nature Neuroscience 18 (4): 603-610. April 2015
74. NF-kappaB function in growth control: Regulation of cyclin D1 expression and G(0)G(1)-to-S-Phase transition.
Hinz, M. and Krappmann, D. and Eichten, A. and Heder, A. and Scheidereit, C. and Strauss, M.
Molecular and Cellular Biology 19 : 2690-2698. 1 April 1999
75. The transcription factor Sox10 is a key regulator of peripheral glial development.
Britsch, S. and Goerich, D.E. and Riethmacher, D. and Peirano, R.I. and Rossner, M. and Nave, K.A. and Birchmeier, C. and Wegner, M.
Genes & Development 15 (1): 66-78. 1 January 2001
76. A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks.
Schuster, S. and Fell, D.A. and Dandekar, T.
Nature Biotechnology 18 (3): 326-332. 1 March 2000
77. Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates.
Mates, L. and Chuah, M.K. and Belay, E. and Jerchow, B. and Manoj, N. and Acosta-Sanchez, A. and Grzela, D.P. and Schmitt, A. and Becker, K. and Matrai, J. and Ma, L. and Samara-Kuko, E. and Gysemans, C. and Pryputniewicz, D. and Miskey, C. and Fletcher, B. and Vandendriessche, T. and Ivics, Z. and Izsvak, Z.
Nature Genetics 41 (6): 753-761. June 2009
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78. Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
Bargou, R.C. and Emmerich, F. and Krappmann, D. and Bommert, K. and Mapara, M.Y. and Arnold, W. and Royer, H.D. and Grinstein, E. and Greiner, A. and Scheidereit, C. and Doerken, B.
Journal of Clinical Investigation 100 (12): 2961-2969. 15 December 1997
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79. Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.
Fujita, Y. and Krause, G. and Scheffner, M. and Zechner, D. and Leddy, H.E.M. and Behrens, J. and Sommer, T. and Birchmeier, W.
Nature Cell Biology 4 (3): 222-231. 1 March 2002
80. Plasma Cytokine Parameters and Mortality in Patients with Chronic Heart Failure.
Rauchhaus, M. and Doehner, W. and Francis, D.P. and Davos, C. and Kemp, M. and Liebenthal, C. and Niebauer, J. and Hooper, J. and Volk, H.D. and Coats, A.J.S. and Anker, S.D.
Circulation 102 (25): 3060-3067. 19 December 2000
81. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
Bork, P. and Hofmann, K. and Bucher, P. and Neuwald, A. and Altschul, S.F. and Koonin, E.V.
FASEB Journal 11 (1): 68-76. 1 January 1997
82. Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M. and Glažar, P. and Hernandez-Miranda, L.R. and Memczak, S. and Wolf, S.A. and Rybak-Wolf, A. and Filipchyk, A. and Klironomos, F. and Cerda Jara, C.A. and Fenske, P. and Trimbuch, T. and Zywitza, V. and Plass, M. and Schreyer, L. and Ayoub, S. and Kocks, C. and Kühn, R. and Rosenmund, C. and Birchmeier, C. and Rajewsky, N.
Science 357 (6357): eaam8526. 22 September 2017
83. Endotoxin and immune activation in chronic heart failure: a prospective cohort study.
Niebauer, J. and Volk, H.D. and Kemp, M. and Dominguez, M. and Schumann, R.R. and Rauchhaus, M. and Poole-Wilson, P.A. and Coats, A.J.S. and Anker, S.D.
Lancet 353 (9167): 1838-1842. 29 May 1999
84. STRING: a web-server to retrieve and display the repeatedly occurring neighbourhood of a gene.
Snel, B. and Lehmann, G. and Bork, P. and Huynen, M.A.
Nucleic Acids Research 28 (18): 3442-3444. 15 September 2000
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85. Isolation of a protein that is essential for the first step of nuclear protein import.
Goerlich, D. and Prehn, S. and Laskey, R.A. and Hartmann, E.
Cell 79 (5): 767-778. 2 December 1994
86. Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment.
Kempermann, G. and Gast, D. and Gage, F.H.
Annals of Neurology 52 (2): 135-143. August 2002
87. Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach.
Floegel, A. and Stefan, N. and Yu, Z. and Mühlenbruch, K. and Drogan, D. and Joost, H.G. and Fritsche, A. and Häring, H.U. and Hrabě de Angelis, M. and Peters, A. and Roden, M. and Prehn, C. and Wang-Sattler, R. and Illig, T. and Schulze, M.B. and Adamski, J. and Boeing, H. and Pischon, T.
Diabetes 62 (2): 639-648. February 2013
88. Analysis of intron sequences reveals hallmarks of circular RNA biogenesis in animals.
Ivanov, A. and Memczak, S. and Wyler, E. and Torti, F. and Porath, H.T. and Orejuela, M.R. and Piechotta, M. and Levanon, E.Y. and Landthaler, M. and Dieterich, C. and Rajewsky, N.
Cell Reports 10 (2): 170-177. 13 January 2015
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89. Microglia in physiology and disease.
Wolf, S.A. and Boddeke, H.W.G.M. and Kettenmann, H.
Annual Review of Physiology 79 : 619-643. February 2017
90. Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection (authors reply inN Engl J Med. 2005 May 12;352(19):2027-8).
Dragun, D. and Mueller, D.N. and Braesen, J.H. and Fritsche, L. and Nieminen-Kelhae, M. and Dechend, R. and Kintscher, U. and Rudolph, B. and Hoebeke, J. and Eckert, D. and Mazak, I. and Plehm, R. and Schoenemann, C. and Unger, T. and Budde, K. and Neumayer, H.H. and Luft, F.C. and Wallukat, G.
New England Journal of Medicine 352 (6): 558-569. 1 January 2005
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91. Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress tumor necrosis factor alpha by phosphorylation.
Rogalla, T. and Ehrnsperger, M. and Preville, X. and Kotlyarov, A. and Lutsch, G. and Ducasse, C. and Paul, C. and Wieske, M. and Arrigo, A.P. and Buchner, J. and Gaestel, M.
Journal of Biological Chemistry 274 (27): 18947-8956. 2 July 1999
92. An empirical framework for binary interactome mapping.
Venkatesan, K. and Rual, J.F. and Vazquez, A. and Stelzl, U. and Lemmens, I. and Hirozane-Kishikawa, T. and Hao, T. and Zenkner, M. and Xin, X. and Goh, K.I. and Yildirim, M.A. and Simonis, N. and Heinzmann, K. and Gebreab, F. and Sahalie, J.M. and Cevik, S. and Simon, C. and de Smet, A.S. and Dann, E. and Smolyar, A. and Vinayagam, A. and Yu, H. and Szeto, D. and Borick, H. and Dricot, A. and Klitgord, N. and Murray, R.R. and Lin, C. and Lalowski, M. and Timm, J. and Rau, K. and Boone, C. and Braun, P. and Cusick, M.E. and Roth, F.P. and Hill, D.E. and Tavernier, J. and Wanker, E.E. and Barabasi, A.L. and Vidal, M.
Nature Methods 6 (1): 83-90. January 2009
93. Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor.
Wallukat, G. and Homuth, V. and Fischer, T. and Lindschau, C. and Horstkamp, B. and Jupner, A. and Baur, E. and Nissen, E. and Vetter, K. and Neichel, D. and Dudenhausen, J.W. and Haller, H. and Luft, F.C.
Journal of Clinical Investigation 103 (7): 945-952. 1 April 1999
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94. Structure and function of the global topsoil microbiome.
Bahram, M. and Hildebrand, F. and Forslund, S.K. and Anderson, J.L. and Soudzilovskaia, N.A. and Bodegom, P.M. and Bengtsson-Palme, J. and Anslan, S. and Coelho, L.P. and Harend, H. and Huerta-Cepas, J. and Medema, M.H. and Maltz, M.R. and Mundra, S. and Olsson, P.A. and Pent, M. and Põlme, S. and Sunagawa, S. and Ryberg, M. and Tedersoo, L. and Bork, P.
Nature 560 (7717): 233-237. 9 August 2018
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95. A side effect resource to capture phenotypic effects of drugs.
Kuhn, M. and Campillos, M. and Letunic, I. and Jensen, L.J. and Bork, P.
Molecular Systems Biology 6 : 343. 2010
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96. Microglia development follows a stepwise program to regulate brain homeostasis.
Matcovitch-Natan, O. and Winter, D.R. and Giladi, A. and Vargas Aguilar, S. and Spinrad, A. and Sarrazin, S. and Ben-Yehuda, H. and David, E. and Zelada González, F. and Perrin, P. and Keren-Shaul, H. and Gury, M. and Lara-Astaiso, D. and Thaiss, C.A. and Cohen, M. and Bahar Halpern, K. and Baruch, K. and Deczkowska, A. and Lorenzo-Vivas, E. and Itzkovitz, S. and Elinav, E. and Sieweke, M.H. and Schwartz, M. and Amit, I.
Science 353 (6301): aad8670. 19 August 2016
97. A human snoRNA with microRNA-like functions.
Ender, C. and Krek, A. and Friedlaender, M.R. and Beitzinger, M. and Weinmann, L. and Chen, W. and Pfeffer, S. and Rajewsky, N. and Meister, G.
Molecular Cell 32 (4): 519-528. 21 November 2008
98. Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Gerull, B. and Heuser, A. and Wichter, T. and Paul, M. and Basson, C.T. and McDermott, D.A. and Lerman, B.B. and Markowitz, S.M. and Ellinor, P.T. and MacRae, C.A. and Peters, S. and Grossmann, K.S. and Drenckhahn, J. and Michely, B. and Sasse-Klaassen, S. and Birchmeier, W. and Dietz, R. and Breithardt, G. and Schulze-Bahr, E. and Thierfelder, L.
Nature Genetics 36 (11): 1162-1164. November 2004
99. E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
Huelsken, J. and Birchmeier, W. and Behrens, J.
Journal of Cell Biology 127 (6 Pt. 2): 2061-2069. December 1994
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100. Glial calcium: Homeostasis and signaling function.
Verkhratsky, A. and Orkand, R.K. and Kettenmann, H.
Physiological Reviews 78 (1): 99-141. January 1998
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