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SMART: a web-based tool for the study of genetically mobile domains

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Item Type:Article
Title:SMART: a web-based tool for the study of genetically mobile domains
Creators Name:Schultz, J. and Copley, R.R. and Doerks, T. and Ponting, C.P. and Bork, P.
Abstract:SMART (a Simple Modular Architecture Research Tool) allows the identification and annotation of genetically mobile domains and the analysis of domain architectures (http://SMART.embl-heidelberg.de ). More than 400 domain families found in signalling, extra-cellular and chromatin-associated proteins are detectable. These domains are extensively annotated with respect to phyletic distributions, functional class, tertiary structures and functionally important residues. Each domain found in a non-redundant protein database as well as search parameters and taxonomic information are stored in a relational database system. User interfaces to this database allow searches for proteins containing specific combinations of domains in defined taxa.
Keywords:Database Management Systems, Information Storage and Retrieval, Proteins, Chemistry, Sequence Alignment
Source:Nucleic Acids Research
ISSN:0305-1048
Publisher:Oxford University Press (U.K.)
Volume:28
Number:1
Page Range:231-234
Date:1 January 2000
Official Publication:http://nar.oxfordjournals.org/cgi/content/abstract/28/1/231
PubMed:View item in PubMed

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