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Phylogenetic ctDNA analysis depicts early stage lung cancer evolution.
Abbosh, C., Birkbak, N.J., Wilson, G.A., Jamal-Hanjani, M., Constantin, T., Salari, R., Quesne, J.L., Moore, D.A., Veeriah, S., Rosenthal, R., Marafioti, T., Kirkizlar, E., Watkins, T.B.K., McGranahan, N., Ward, S., Martinson, L., Riley, J., Fraioli, F., Bakir, M.A., Grönroos, E., Zambrana, F., Endozo, R., Bi, W.L., Fennessy, F.M., Sponer, N., Johnson, D., Laycock, J., Shafi, S., Czyzewska-Khan, J., Rowan, A., Chambers, T., Matthews, N., Turajlic, S., Hiley, C., Lee, S.M., Forster, M.D., Ahmad, T., Falzon, M., Borg, E., Lawrence, D., Hayward, M., Kolvekar, S., Panagiotopoulos, N., Janes, S.M., Thakrar, R., Ahmed, A., Blackhall, F., Summers, Y., Hafez, D., Naik, A., Ganguly, A., Kareht, S., Shah, R., Joseph, L., Quinn, A.M., Crosbie, P., Naidu, B., Middleton, G., Langman, G., Trotter, S., Nicolson, M., Remmen, H., Kerr, K., Chetty, M., Gomersall, L., Fennell, D.A., Nakas, A., Rathinam, S., Anand, G., Khan, S., Russell, P., Ezhil, V., Ismail, B., Irvin-Sellers, M., Prakash, V., Lester, J.F., Kornaszewska, M., Attanoos, R., Adams, H., Davies, H., Oukrif, D., Akarca, A.U., Hartley, J.A., Lowe, H.L., Lock, S., Iles, N., Bell, H., Ngai, Y., Elgar, G., Szallasi, Z., Schwarz, R.F., Herrero, J., Stewart, A., Quezada, S.A., Van Loo, P., Dive, C., Lin, C.J., Rabinowitz, M., Aerts, H.J.W.L., Hackshaw, A., Shaw, J.A., Zimmermann, B.G. and Swanton, C.
Nature 545
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25 May 2017
Validity and reliability of total body volume and relative body fat mass from a 3-dimensional photonic body surface scanner.
Adler, C., Steinbrecher, A., Jaeschke, L., Mähler, A., Boschmann, M., Jeran, S. and Pischon, T.
PLoS ONE 12
(7): e0180201.
3 July 2017
Patched receptors sense, interpret and establish an epidermal Hedgehog signalling gradient.
Adolphe, C., Junker, J.P., Lyubimova, A., van Oudenaarden, A. and Wainwright, B.
Journal of Investigative Dermatology 137
(1): 179-186.
January 2017
Genetic heterogeneity in Pakistani microcephaly families revisited.
Ahmad, I., Baig, S.M., Abdulkareem, A.R., Hussain, M.S., Sur, I., Toliat, M.R., Nürnberg, G., Dalibor, N., Moawia, A., Waseem, S.S., Asif, M., Nagra, H., Sher, M., Khan, M.M.A., Hassan, I., Rehman, S.U., Thiele, H., Altmüller, J., Noegel, A.A. and Nürnberg, P.
Clinical Genetics 92
(1): 62-68.
July 2017
Toxoplasma co-infection prevents Th2 differentiation and leads to a helminth-specific Th1 response.
Ahmed, N., French, T., Rausch, S., Kühl, A., Hemminger, K., Dunay, I.R., Steinfelder, S. and Hartmann, S.
Frontiers in Cellular and Infection Microbiology 7
: 341.
25 July 2017
Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A., Xavier, A., Abu Lubad, M., Sigulla, J., Kessler, M., Hurwitz, R. and Meyer, T.F.
EBioMedicine 23
: 100-110.
September 2017
Late diagnosis of a truncating WISP3 mutation entails a severe phenotype of progressive pseudorheumatoid dysplasia.
Alawbathani, S., Kawalia, A., Karakaya, M., Altmüller, J., Nürnberg, P. and Cirak, S.
Cold Spring Harbor Molecular Case Studies 4
(1): a002139.
19 December 2017
Viral to metazoan marine plankton nucleotide sequences from the Tara Oceans expedition.
Alberti, A., Poulain, J., Engelen, S., Labadie, K., Romac, S., Ferrera, I., Albini, G., Aury, J.M., Belser, C., Bertrand, A., Cruaud, C., Da Silva, C., Dossat, C., Gavory, F., Gas, S., Guy, J., Haquelle, M., Jacoby, E., Jaillon, O., Lemainque, A., Pelletier, E., Samson, G., Wessner, M., Acinas, S.G., Royo-Llonch, M., Cornejo-Castillo, F.M., Logares, R., Fernandez-Gomez, B., Bowler, C., Cochrane, G., Amid, C., Hoopen, P.T., De Vargas, C., Grimsley, N., Desgranges, E., Kandels-Lewis, S., Ogata, H., Poulton, N., Sieracki, M.E., Stepanauskas, R., Sullivan, M.B., Brum, J.R., Duhaime, M.B., Poulos, B.T., Hurwitz, B.L., Pesant, S., Karsenti, E. and Wincker, P.
Scientific Data 4
: 170093.
1 August 2017
Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension.
Albrecht, P., Blasberg, C., Ringelstein, M., Mueller, A.K., Finis, D., Guthoff, R., Kadas, E.M., Lagreze, W., Aktas, O., Hartung, H.P., Paul, F., Brandt, A.U. and Methner, A.
Journal of Neurology 264
(7): 1370-1380.
July 2017
Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort.
Aleksandrova, K., Jenab, M., Leitzmann, M., Bueno-de-Mesquita, B., Kaaks, R., Trichopoulou, A., Bamia, C., Lagiou, P., Rinaldi, S., Freisling, H., Carayol, M., Pischon, T., Drogan, D., Weiderpass, E., Jakszyn, P., Overvad, K., Dahm, C.C., Tjønneland, A., Bouton-Ruault, M.C., Kühn, T., Peppa, E., Valanou, E., La Vecchia, C., Palli, D., Panico, S., Sacerdote, C., Agnoli, C., Tumino, R., May, A., van Vulpen, J., Benjaminsen Borch, K., Oluwafemi Oyeyemi, S., Quirós, J.R., Bonet, C., Sánchez, M.J., Dorronsoro, M., Navarro, C., Barricarte, A., van Guelpen, B., Wennberg, P., Key, T.J., Khaw, K.T., Wareham, N., Assi, N., Ward, H.A., Aune, D., Riboli, E. and Boeing, H.
International Journal of Epidemiology 46
(6): 1823-1835.
1 December 2017
Metabolic mediators of the association between adult weight gain and colorectal cancer: data from the european prospective investigation into cancer and nutrition (EPIC) cohort.
Aleksandrova, K., Schlesinger, S., Fedirko, V., Jenab, M., Bueno-de-Mesquita, B., Freisling, H., Romieu, I., Pischon, T., Kaaks, R., Gunter, M.J., Dahm, C.C., Overvad, K., Rostgaard-Hansen, A.L., Tjønneland, A., Trichopoulou, A., Bamia, C., Lagiou, P., Agnoli, C., Mattiello, A., Bradbury, K., Khaw, K.T., Riboli, E. and Boeing, H.
American Journal of Epidemiology 185
(9): 751-764.
May 2017
Cell fixation and preservation for droplet-based single-cell transcriptomics.
Alles, J., Karaiskos, N., Praktiknjo, S.D., Grosswendt, S., Wahle, P., Ruffault, P.L., Ayoub, S., Schreyer, L., Boltengagen, A., Birchmeier, C., Zinzen, R., Kocks, C. and Rajewsky, N.
BMC Biology 15
(1): 44.
19 May 2017
Mutational profiling in the peripheral blood leukocytes of patients with systemic mast cell activation syndrome using next-generation sequencing.
Altmüller, J., Haenisch, B., Kawalia, A., Menzen, M., Nöthen, M.M., Fier, H. and Molderings, G.J.
Immunogenetics 69
(6): 359-369.
June 2017
Satb2(Cre/+) mouse as a tool to investigate cell fate determination in the developing neocortex.
Ambrozkiewicz, M.C., Bessa, P., Salazar-Lázaro, A., Salina, V. and Tarabykin, V.
Journal of Neuroscience Methods 291
: 113-121.
1 November 2017
The immune system prevents recurrence of transplanted but not autochthonous antigenic tumors after oncogene inactivation therapy.
Anders, K., Kershaw, O., Larue, L., Gruber, A.D. and Blankenstein, T.
International Journal of Cancer 141
(12): 2551-2561.
15 December 2017
Aggregation of full length immunoglobulin light chains from AL amyloidosis patients is remodeled by epigallocatechin-3-gallate.
Andrich, K., Hegenbart, U., Kimmich, C., Kedia, N., Bergen, H.R., Schönland, S., Wanker, E.E. and Bieschke, J.
Journal of Biological Chemistry 292
(6): 2328-2344.
10 February 2017
Discovery of a novel series of tankyrase inhibitors by a hybridization approach.
Anumala, U.R., Waaler, J., Nkizinkiko, Y., Ignatev, A., Lazarow, K., Lindemann, P., Olsen, P.A., Murthy, S., Obaji, E., Majouga, A.G., Leonov, S., von Kries, J.P., Lehtiö, L., Krauss, S. and Nazaré, M.
Journal of Medicinal Chemistry 60
(24): 10013-10025.
28 December 2017
Touch receptor-derived sensory information alleviates acute pain signaling and fine-tunes nociceptive reflex coordination.
Arcourt, A., Gorham, L., Dhandapani, R., Prato, V., Taberner, F.J., Wende, H., Gangadharan, V., Birchmeier, C., Heppenstall, P.A. and Lechner, S.G.
Neuron 93
(1): 179-193.
4 January 2017
Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma.
Arslan, A.D., Sassano, A., Saleiro, D., Lisowski, P., Kosciuczuk, E.M., Fischietti, M., Eckerdt, F., Fish, E.N. and Platanias, L.C.
Oncogene 36
(43): 6006-6019.
26 October 2017
Disruption of the leptomeningeal blood barrier in neuromyelitis optica spectrum disorder.
Asgari, N., Flanagan, E.P., Fujihara, K., Kim, H.J., Skejoe, H.P., Wuerfel, J., Kuroda, H., Kim, S.H., Maillart, E., Marignier, R., Pittock, S.J., Paul, F. and Weinshenker, B.G.
Neurology Neuroimmunology & Neuroinflammation 4
(4): e343.
July 2017
Insulin-like growth factor (IGF) binding protein-2, independently of IGF-1, induces GLUT-4 translocation and glucose uptake in 3T3-L1 adipocytes.
Assefa, B., Mahmoud, A.M., Pfeiffer, A.F.H., Birkenfeld, A.L., Spranger, J. and Arafat, A.M.
Oxidative Medicine and Cellular Longevity 2017
: 3035184.
20 December 2017
Collagen cell carriers seeded with human urothelial cells for urethral reconstructive surgery: first results in a xenograft minipig model.
Aufderklamm, S., Vaegler, M., Kelp, A., Maurer, S., Gustafsson, L., Mundhenk, J., Busch, S., Daum, L., Stenzl, A., Amend, B. and Sievert, K.D.
World Journal of Urology 35
(7): 1125-1132.
July 2017
A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle.
Awazawa, M., Gabel, P., Tsaousidou, E., Nolte, H., Krüger, M., Schmitz, J., Ackermann, P.J., Brandt, C., Altmüller, J., Motameny, S., Wunderlich, F.T., Kornfeld, J.W., Blüher, M. and Brüning, J.C.
Nature Medicine 23
(12): 1466-1473.
1 December 2017
RNA-bioinformatics: tools, services and databases for the analysis of RNA-based regulation.
Backofen, R., Engelhardt, J., Erxleben, A., Fallmann, J., Grüning, B., Ohler, U., Rajewsky, N. and Stadler, P.F.
Journal of Biotechnology 261
: 76-84.
10 November 2017
Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis.
Baddack-Werncke, U., Busch-Dienstfertig, M., Gonzalez-Rodriguez, S., Maddila, S.C., Grobe, J., Lipp, M., Stein, C. and Mueller, G.
Journal of Neuroinflammation 14
(1): 30.
6 February 2017
Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium.
Balzus, B., Sahle, F.F., Hönzke, S., Gerecke, C., Schumacher, F., Hedtrich, S., Kleuser, B. and Bodmeier, R.
European Journal of Pharmaceutics and Biopharmaceutics 115
: 122-130.
June 2017
Subsequent malignancies among long-term survivors of Hodgkin lymphoma and non-Hodgkin lymphoma: a pooled analysis of German cancer registry data (1990-2012).
Baras, N., Dahm, S., Haberland, J., Janz, M., Emrich, K., Kraywinkel, K. and Salama, A.
British Journal of Haematology 177
(2): 226-242.
April 2017
Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells.
Barbieri, M., Xie, S.Q., Torlai Triglia, E., Chiariello, A.M., Bianco, S., de Santiago, I., Branco, M.R., Rueda, D., Nicodemi, M. and Pombo, A.
Nature Structural & Molecular Biology 24
(6): 515-524.
June 2017
Complex multi-enhancer contacts captured by genome architecture mapping.
Beagrie, R.A., Scialdone, A., Schueler, M., Kraemer, D.C.A., Chotalia, M., Xie, S.Q., Barbieri, M., de Santiago, I., Lavitas, L.M., Branco, M.R., Fraser, J., Dostie, J., Game, L., Dillon, N., Edwards, P.A.W., Nicodemi, M. and Pombo, A.
Nature 543
(7646): 519-524.
23 March 2017
Elastase-2, a tissue alternative pathway for angiotensin II generation, plays a role in circulatory sympathovagal balance in mice.
Becari, C., Durand, M.T., Guimaraes, A.O., Lataro, R.M., Prado, C.M., de Oliveira, M., Candido, S.C.O., Pais, P., Ribeiro, M.S., Bader, M., Pesquero, J.B., Salgado, M.C.O. and Salgado, H.C.
Frontiers in Physiology 8
: 170.
23 March 2017
Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naive Parkinson's disease patients.
Bedarf, J.R., Hildebrand, F., Coelho, L.P., Sunagawa, S., Bahram, M., Goeser, F., Bork, P. and Wuellner, U.
Genome Medicine 9
(1): 39.
28 April 2017
Mathematical modelling of promoter occupancies in MYC-dependent gene regulation.
Benary, U., Wolf, E. and Wolf, J.
Genomics and Computational Biology 3
(2): e54.
2017
Proarrhythmic remodelling of the right ventricle in a porcine model of repaired tetralogy of Fallot.
Benoist, D., Dubes, V., Roubertie, F., Gilbert, S.H., Charron, S., Constantin, M., Elbes, D., Vieillot, D., Quesson, B., Cochet, H., Haissaguerre, M., Rooryck, C., Bordachar, P., Thambo, J.B. and Bernus, O.
Heart 103
(5): 347-354.
March 2017
Ligand-specific restriction of extracellular conformational dynamics constrains signaling of the M(2) muscarinic receptor.
Bermudez, M., Bock, A., Krebs, F., Holzgrabe, U., Mohr, K., Lohse, M.J. and Wolber, G.
ACS Chemical Biology 12
(7): 1743-1748.
21 July 2017
Genetic tracing of Ca(V)3.2 T-type calcium channel expression in the peripheral nervous system.
Bernal Sierra, Y.A., Haseleu, J., Kozlenkov, A., Bégay, V. and Lewin, G.R.
Frontiers in Molecular Neuroscience 10
(70): 70.
15 March 2017
Inflammation-induced brain endothelial activation leads to uptake of electrostatically stabilized iron oxide nanoparticles via sulfated glycosaminoglycans.
Berndt, D., Millward, J.M., Schnorr, J., Taupitz, M., Stangl, V., Paul, F., Wagner, S., Wuerfel, J.T., Sack, I., Ludwig, A. and Infante-Duarte, C.
Nanomedicine: Nanotechnology, Biology and Medicine 13
(4): 1411-1421.
May 2017
Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism.
Biagosch, C., Ediga, R.D., Hensler, S.V., Faerberboeck, M., Kuehn, R., Wurst, W., Meitinger, T., Kölker, S., Sauer, S. and Prokisch, H.
Biochimica et Biophysica Acta - Molecular Basis of Disease 1863
(9): 2220-2228.
September 2017
On mass ambiguities in high-resolution shotgun lipidomics.
Bielow, C., Mastrobuoni, G., Orioli, M. and Kempa, S.
Analytical Chemistry 89
(5): 2986-2994.
7 March 2017
Identification and functional characterization of hypoxia-induced endoplasmic reticulum stress regulating lncRNA (HypERlnc) in pericytes.
Bischoff, F.C., Werner, A., John, D., Boeckel, J.-N., Melissari, M.-T., Grote, P., Glaser, S.F., Demolli, S., Uchida, S., Michalik, K.M., Meder, B., Katus, H.A., Haas, J., Chen, W., Pullamsetti, S.S., Seeger, W., Zeiher, A.M., Dimmeler, S. and Zehendner, C.M.
Circulation Research 121
(4): 368-375.
4 August 2017
Calcineurin inhibitor cyclosporine a activates renal Na-K-Cl cotransporters via local and systemic mechanisms.
Blankenstein, K.I., Borschewski, A., Labes, R., Paliege, A., Boldt, C., McCormick, J.A., Ellison, D.H., Bader, M., Bachmann, S. and Mutig, K.
American Journal of Physiology Renal Physiology 312
(3): F489-F501.
2 March 2017
Influence of spatial resolution and contrast agent dosage on myocardial T1 relaxation times.
Blaszczyk, E., Töpper, A., Schmacht, L., Wanke, F., Greiser, A., Schulz-Menger, J. and von Knobelsdorff-Brenkenhoff, F.
Magnetic Resonance Materials in Physics Biology and Medicine 30
(1): 85-91.
February 2017
A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y., Malehmir, M., Healy, M.E., Bettermann, K., Lorentzen, A., Vucur, M., Ahuja, A.K., Böhm, F., Mertens, J.C., Shimizu, Y., Frick, L., Remouchamps, C., Mutreja, K., Kähne, T., Sundaravinayagam, D., Wolf, M.J., Rehrauer, H., Koppe, C., Speicher, T., Padrissa-Altés, S., Maire, R., Schattenberg, J.M., Jeong, J.S., Liu, Lei, Zwirner, S., Boger, R., Hüser, N., Davis, R.J., Müllhaupt, B., Moch, H., Schulze-Bergkamen, H., Clavien, P.A., Werner, S., Borsig, L., Luther, S.A., Jost, P.J., Weinlich, R., Unger, K., Behrens, A., Hillert, L., Dillon, C., Di Virgilio, M., Wallach, D., Dejardin, E., Zender, L., Naumann, M., Walczak, H., Green, D.R., Lopes, M., Lavrik, I., Luedde, T., Heikenwalder, M. and Weber, A.
Cancer Cell 32
(3): 342-359.
11 September 2017
Polysialic acid regulates sympathetic outflow by facilitating information transfer within the nucleus of the solitary tract.
Bokiniec, P., Shahbazian, S., McDougall, S.J., Berning, B.A., Cheng, D., Llewellyn-Smith, I.J., Burke, P.G.R., McMullan, S., Muehlenhoff, M., Hildebrandt, H., Braet, F., Connor, M., Packer, N.H. and Goodchild, A.K.
Journal of Neuroscience 37
(27): 6558-6574.
5 July 2017
Influence of female sex and fertile age on neuromyelitis optica spectrum disorders.
Borisow, N., Kleiter, I., Gahlen, A., Fischer, K., Wernecke, K.D., Pache, F., Ruprecht, K., Havla, J., Krumbholz, M., Kümpfel, T., Aktas, O., Ringelstein, M., Geis, C., Kleinschnitz, C., Berthele, A., Hemmer, B., Angstwurm, K., Weissert, R., Stellmann, J.P., Schuster, S., Stangel, M., Lauda, F., Tumani, H., Mayer, C., Zeltner, L., Ziemann, U., Linker, R.A., Schwab, M., Marziniak, M., Then Bergh, F., Hofstadt-van Oy, U., Neuhaus, O., Winkelmann, A., Marouf, W., Rückriem, L., Faiss, J., Wildemann, B., Paul, F., Jarius, S., Trebst, C. and Hellwig, K.
Multiple Sclerosis Journal 23
(8): 1092-1103.
July 2017
Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study.
Bove, R., Elsone, L., Alvarez, E., Borisow, N., Cortez, M.M., Mateen, F.J., Mealy, M.A., Mutch, K., Tobyne, S., Ruprecht, K., Buckle, G., Levy, M., Wingerchuk, D.M., Paul, F., Cross, A.H., Weinshenker, B., Jacob, A., Klawiter, E.C. and Chitnis, T.
Neurology Neuroimmunology & Neuroinflammation 4
(3): e339.
May 2017
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Bowl, M.R., Simon, M.M., Ingham, N.J., Greenaway, S., Santos, L., Cater, H., Taylor, S., Mason, J., Kurbatova, N., Pearson, S., Bower, L.R., Clary, D.A., Meziane, H., Reilly, P., Minowa, O., Kelsey, L., Tocchini-Valentini, G.P., Gao, X., Bradley, A., Skarnes, W.C., Moore, M., Beaudet, A.L., Justice, M.J., Seavitt, J., Dickinson, M.E., Wurst, W., Hrabe de Angelis, M., Herault, Y., Wakana, S., Nutter, L.M.J., Flenniken, A.M., McKerlie, C., Murray, S.A., Svenson, K.L., Braun, R.E., West, D.B., Lloyd, K.C.K., Adams, D.J., White, J., Karp, N., Flicek, P., Smedley, D., Meehan, T.F., Parkinson, H.E., Teboul, L.M., Wells, S., Steel, K.P., Mallon, A.M. and Brown, S.D.M.
Nature Communications 8
(1): 886.
12 October 2017
Lipidome determinants of maximal lifespan in mammals.
Bozek, K., Khrameeva, E.E., Reznick, J., Omerbašić, D., Bennett, N.C., Lewin, G.R., Azpurua, J., Gorbunova, V., Seluanov, A., Regnard, P., Wanert, F., Marchal, J., Pifferi, F., Aujard, F., Liu, Z., Shi, P., Pääbo, S., Schroeder, F., Willmitzer, L., Giavalisco, P. and Khaitovich, P.
Scientific Reports 7
: 5.
31 January 2017
Heterozygous HNRNPU variants cause early onset epilepsy and severe intellectual disability.
Bramswig, N.C., Lüdecke, H.J., Hamdan, F.F., Altmüller, J., Beleggia, F., Elcioglu, N.H., Freyer, C., Gerkes, E.H., Demirkol, Y.K., Knupp, K.G., Kuechler, A., Li, Y., Lowenstein, D.H., Michaud, J.L., Park, K., Stegmann, A.P.A., Veenstra-Knol, H.E., Wieland, T., Wollnik, B., Engels, H., Strom, T.M., Kleefstra, T. and Wieczorek, D.
Human Genetics 136
(7): 821-834.
July 2017
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.
Brocks, D., Schmidt, C.R., Daskalakis, M., Jang, H.S., Shah, N.M., Li, D., Li, J., Zhang, B., Hou, Y., Laudato, S., Lipka, D.B., Schott, J., Bierhoff, H., Assenov, Y., Helf, M., Ressnerova, A., Islam, M.S., Lindroth, A.M., Haas, S., Essers, M., Imbusch, C.D., Brors, B., Oehme, I., Witt, O., Lübbert, M., Mallm, J.P., Rippe, K., Will, R., Weichenhan, D., Stoecklin, G., Gerhäuser, C., Oakes, C.C., Wang, T. and Plass, C.
Nature Genetics 49
(7): 1052-1060.
July 2017
Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities.
Bunina, D., Štefl, M., Huber, F., Khmelinskii, A., Meurer, M., Barry, J.D., Kats, I., Kirrmaier, D., Huber, W. and Knop, M.
Nucleic Acids Research 45
(19): 11144-11158.
2 November 2017
Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Buonocore, F., Kuehnen, P., Suntharalingham, J.P., Del Valle, I., Digweed, M., Stachelscheid, H., Khajavi, N., Didi, M., Brady, A.F., Blankenstein, O., Procter, A.M., Dimitri, P., Wales, J.K.H., Ghirri, P., Knoebl, D., Strahm, B., Erlacher, M., Wlodarski, M.W., Chen, W., Kokai, G.K., Anderson, G., Morrogh, D., Moulding, D.A., McKee, S. A., Niemeyer, C.M., Grueters, A. and Achermann, J.C.
Journal of Clinical Investigation 127
(5): 1700-1713.
1 May 2017
Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies.
Burghi, V., Fernández, N.C., Gándola, Y.B., Piazza, V.G., Quiroga, D.T., Guilhen Mario, E., Felix Braga, J., Bader, M., Santos, R.A.S., Dominici, F.P. and Munoz, M.C.
PLoS ONE 12
(8): e0183278.
16 August 2017
Role of IL-17-producing lymphocytes in severity of multiple sclerosis upon natalizumab treatment.
Bühler, U., Fleischer, V., Luessi, F., Rezk, A., Belikan, P., Graetz, C., Gollan, R., Wolf, C., Lutz, J., Bar-Or, A., Siffrin, V. and Zipp, F.
Multiple Sclerosis Journal 23
(4): 567-576.
1 April 2017
Mapping interpuff interval distribution to the properties of inositol trisphosphate receptors.
Cao, P., Falcke, M. and Sneyd, J.
Biophysical Journal 112
(10): 2138-2146.
23 May 2017
Experimental validation of a preclinical SPECT/MR insert.
Carminati, M., Occhipinti, M., Baratelli, F. M., Montagnani, G. L., Nagy, K., Nyitrai, Z., Nagy, A., Czeller, M., Kühne, A., Niendorf, T., Mathe, D., Belloli, S., Valtorta, S., Moresco, R. M., Falini, A., Iadanza, A., Ottobrini, L. and Fiorini, C.
IEEE Nuclear Science Symposium and Medical Imaging Conference
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2017
Identification of a novel benzimidazole pyrazolone scaffold that inhibits KDM4 lysine demethylases and reduces proliferation of prostate cancer cells.
Carter, D.M., Specker, E., Przygodda, J., Neuenschwander, M., von Kries, J.P., Heinemann, U., Nazaré, M. and Gohlke, U.
SLAS Discovery 22
(7): 801-812.
1 August 2017
Serotonin regulates prostate growth through androgen receptor modulation.
Carvalho-Dias, E., Miranda, A., Martinho, O., Mota, P., Costa, A., Nogueira-Silva, C., Moura, R.S., Alenina, N., Bader, M., Autorino, R., Lima, E. and Correia-Pinto, J.
Scientific Reports 7
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13 November 2017
Impaired vitreous composition and retinal pigment epithelium function in the FoxG1::LRP2 myopic mice.
Cases, O., Obry, A., Ben-Yacoub, S., Augustin, S., Joseph, A., Toutirais, G., Simonutti, M., Christ, A., Cosette, P. and Kozyraki, R.
Biochimica et Biophysica Acta - Molecular Cell Research 1863
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June 2017
Dynamo Catalogue: geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms.
Castaño-Díez, D., Kudryashev, M. and Stahlberg, H.
Journal of Structural Biology 197
(2): 135-144.
February 2017
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N., Naumann, H., Ruzittu, S., Mah, N., Pongrac, I.M., Cozzitorto, C., Hommel, A., Andrade-Navarro, M.A., Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8
: 14127.
13 February 2017
OGEE v2: an update of the online gene essentiality database with special focus on differentially essential genes in human cancer cell lines.
Chen, W.H., Lu, G., Chen, X., Zhao, X.M. and Bork, P.
Nucleic Acids Research 45
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4 January 2017
Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X., Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214
(11): 3417-3433.
6 November 2017
Cellular and molecular identity of tumor-associated macrophages in glioblastoma.
Chen, Z., Feng, X., Herting, C.J., Alvarez Garcia, V., Nie, K., Pong, W.W., Rasmussen, R., Dwivedi, B., Seby, S., Wolf, S.A., Gutmann, D.H. and Hambardzumyan, D.
Cancer Research 77
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1 May 2017
Structural characterization and ligand/inhibitor identification provide functional insights into the mycobacterium tuberculosis cytochrome P450 CYP126A1.
Chenge, J.T., Duyet, L.V., Swami, S., McLean, K.J., Kavanagh, M.E., Coyne, A.G., Rigby, S.E.J., Cheesman, M.R., Girvan, H.M., Levy, C.W., Rupp, B., von Kries, J.P., Abell, C., Leys, D. and Munro, A.W.
Journal of Biological Chemistry 292
(4): 1310-1329.
27 January 2017
Quantitative profiling of hydroxy lipid metabolites in mouse organs reveals distinct lipidomic profiles and modifications due to elevated n-3 fatty acid levels.
Chiu, C.Y., Smyl, C., Dogan, I., Rothe, M. and Weylandt, K.H.
Biology 6
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4 February 2017
Endothelial NF-κB blockade abrogates ANCA-induced GN.
Choi, M., Schreiber, A., Eulenberg-Gustavus, C., Scheidereit, C., Kamps, J. and Kettritz, R.
Journal of the American Society of Nephrology 28
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November 2017
CRISPR/Cas9-mediated in vitro mutagenesis in GC-like B cells.
Chu, V.T., Graf, R. and Rajewsky, K.
Methods in Molecular Biology 1623
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2017
Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods.
Churko, J.M., Lee, J., Ameen, M., Gu, M., Venkatasubramanian, M., Diecke, S., Sallam, K., Im, H., Wang, G., Gold, J.D., Salomonis, N., Snyder, M.P. and Wu, J.C.
Nature Biomedical Engineering 1
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October 2017
C/EBP-induced transdifferentiation reveals granulocyte-macrophage precursor-like plasticity of B cells.
Cirovic, B., Schönheit, J., Kowenz-Leutz, E., Ivanovska, J., Klement, C., Pronina, N., Bégay, V. and Leutz, A.
Stem Cell Reports 14
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14 February 2017
Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat.
Coan, P.M., Hummel, O., Diaz, A.I.G., Barrier, M., Alfazema, N., Norsworthy, P.J., Pravenec, M., Petretto, E., Hübner, N. and Aitman, T.J.
Disease Models & Mechanisms 10
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1 March 2017
Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Consentius, P., Gohlke, U., Loll, B., Alings, C., Heinemann, U., Wahl, M.C. and Risse, T.
Physical Chemistry Chemical Physics 19
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9 August 2017
Internal dynamics of the 3-pyrroline-N-oxide ring in spin-labeled proteins.
Consentius, P., Loll, B., Gohlke, U., Alings, C., Müller, C., Müller, R., Teutloff, C., Heinemann, U., Kaupp, M., Wahl, M.C. and Risse, T.
Journal of Physical Chemistry Letters 8
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16 March 2017
Prevalence of metabolic syndrome in female and male patients at risk of psychosis.
Cordes, J., Bechdolf, A., Engelke, C., Kahl, K.G., Balijepalli, C., Loesch, C., Klosterkoetter, J., Wagner, M., Maier, W., Heinz, A., de Millas, W., Gaebel, W., Winterer, G., Janssen, B., Schmidt-Kraepelin, C., Schneider, F., Lambert, M., Juckel, G., Wobrock, T., Riedel, M. and Moebus, S.
Schizophrenia Research 181
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March 2017
Guidelines for the use of flow cytometry and cell sorting in immunological studies (first edition).
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European Journal of Immunology 47
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11 October 2017
Subspecies in the global human gut microbiome.
Costea, P.I., Coelho, L.P., Sunagawa, S., Munch, R., Huerta-Cepas, J., Forslund, K., Hildebrand, F., Kushugulova, A., Zeller, G. and Bork, P.
Molecular Systems Biology 13
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14 December 2017
MetaSNV: a tool for metagenomic strain level analysis.
Costea, P.I., Munch, R., Coelho, L.P., Paoli, L., Sunagawa, S. and Bork, P.
PLoS ONE 12
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28 July 2017
Towards standards for human fecal sample processing in metagenomic studies.
Costea, P.I., Zeller, G., Sunagawa, S., Pelletier, E., Alberti, A., Levenez, F., Tramontano, M., Driessen, M., Hercog, R., Jung, F.E., Kultima, J.R., Hayward, M.R., Coelho, L.P., Allen-Vercoe, E., Bertrand, L., Blaut, M., Brown, J.R.M., Carton, T., Cools-Portier, S., Daigneault, M., Derrien, M., Druesne, A., de Vos, W.M., Finlay, B.B., Flint, H.J., Guarner, F., Hattori, M., Heilig, H., Luna, R.A., van Hylckama Vlieg, J., Junick, J., Klymiuk, I., Langella, P., Le Chatelier, Z., Mai, V., Manichanh, C., Martin, J.C., Mery, C., Morita, H., O'Toole, P.W., Orvain, C., Patil, K.R., Penders, J., Persson, S., Pons, N., Popova, M., Salonen, A., Saulnier, D., Scott, K.P., Singh, B., Slezak, K., Veiga, P., Versalovic, J., Zhao, L., Zoetendal, E.G., Ehrlich, S.D., Dore, J. and Bork, P.
Nature Biotechnology 35
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November 2017
Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.
Cui, H., Bansal, V., Grunert, M., Malecova, B., Dall Agnese, A., Latella, L., Gatto, S., Ryan, T., Schulz, K., Chen, W., Dorn, C., Puri, P.L. and Sperling, S.R.
PLoS ONE 12
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13 June 2017
Control of gene editing by manipulation of DNA repair mechanisms.
Danner, E., Bashir, S., Yumlu, S., Wurst, W., Wefers, B. and Kühn, R.
Mammalian Genome 28
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August 2017
Improved cardiovascular autonomic modulation in transgenic rats expressing an Ang-(1-7)-producing fusion protein.
Dartora, D.R., Irigoyen, M.C., Casali, K.R., Moraes-Silva, I.C., Bertagnolli, M., Bader, M. and Santos, R.
Canadian Journal of Physiology and Pharmacology 95
(9): 993-998.
September 2017
Channeling of branched flow in weakly scattering anisotropic media.
Degueldre, H., Metzger, J.J., Schultheis, E. and Fleischmann, R.
Physical Review Letters 118
(2): 024301.
13 January 2017
The MYCmRNA3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.
Dejure, F.R., Royla, N., Herold, S., Kalb, J., Walz, S., Ade, C.P., Mastrobuoni, G., Vanselow, J.T., Schlosser, A., Wolf, E., Kempa, S. and Eilers, M.
EMBO Journal 36
(13): 1854-1868.
3 July 2017
The 4D nucleome project.
Dekker, J., Belmont, A.S., Guttman, M., Leshyk, V.O., Lis, J.T., Lomvardas, S., Mirny, L.A., O'Shea, C.C., Park, P.J., Ren, B., Politz, J.C.R., Shendure, J. and Zhong, S.
Nature 549
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14 September 2017
Copy number increases of transposable elements and protein-coding genes in an invasive fish of hybrid origin.
Dennenmoser, S., Sedlazeck, F.J., Iwaszkiewicz, E., Li, X.Y., Altmüller, J. and Nolte, A.W.
Molecular Ecology 26
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26 September 2017
Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress.
Devos, S., Van Putte, W., Vitse, J., Van Driessche, G., Stremersch, S., Van Den Broek, W., Raemdonck, K., Braeckmans, K., Stahlberg, H., Kudryashev, M., Savvides, S.N. and Devreese, B.
Environmental Microbiology 19
(10): 3930-3937.
October 2017
Hypoxia-inducible factor-1α inhibition modulates airway hyperresponsiveness and nitric oxide levels in a BALB/c mouse model of asthma.
Dewitz, C., McEachern, E., Shin, S., Akong, K., Nagle, D.G., Broide, D.H., Akuthota, P. and Crotty Alexander, L.E.
Clinical Immunology 176
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March 2017
Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain.
DiCara, D.M., Chirgadze, D.Y., Pope, A.R., Karatt-Vellatt, A., Winter, A., Slavny, P., van den Heuvel, J., Parthiban, K., Holland, J., Packman, L.C., Mavria, G., Hoffmann, J., Birchmeier, W., Gherardi, E. and McCafferty, J.
Scientific Reports 7
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21 August 2017
Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis.
Dianzani, C., Bellavista, E., Liepe, J., Verderio, Cl., Martucci, M., Santoro, A., Chiocchetti, A., Luca Gigliotti, C., Boggio, E., Ferrara, B., Riganti, L., Keller, C., Janek, K., Niewienda, A., Fenoglio, C., Sorosina, M., Cantello, R., Kloetzel, P.M., Stumpf, M.P.H., Paul, F., Ruprecht, K., Galimberti, D., Martinelli Boneschi, F., Comi, C., Dianzani, U. and Mishto, M.
Scientific Reports 7
: 43718.
9 March 2017
Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.
Dimitrakopoulou, V.I., Tsilidis, K.K., Haycock, P.C., Dimou, N.L., Al-Dabhani, K., Martin, R.M., Lewis, S.J., Gunter, M.J., Mondul, A., Shui, I.M., Theodoratou, E., Nimptsch, K., Lindstroem, S., Albanes, D., Kuehn, T., Key, T.J., Travis, R.C., Vimaleswaran, K.S., Kraft, P., Pierce, B.L. and Schildkraut, J.M.
BMJ 359
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31 October 2017
Claudin peptidomimetics modulate tissue barriers for enhanced drug delivery.
Dithmer, S., Staat, C., Müller, C., Ku, M.C., Pohlmann, A., Niendorf, T., Gehne, N., Fallier-Becker, P., Kittel, Á., Walter, F.R., Veszelka, S., Deli, M.A., Blasig, R., Haseloff, R.F., Blasig, I.E. and Winkler, L.
Annals of the New York Academy of Sciences 1397
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June 2017
Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J., Neuenschwander, M., Yu, Y., Däbritz, J.H.M., Neuendorff, N.R., Schleich, K., Bittner, A., Milanovic, M., Beuster, G., Radetzki, S., Specker, E., Reimann, M., Rosenbauer, F., Mathas, S., Lohneis, P., Hummel, M., Dörken, B., von Kries, J.P., Lee, S. and Schmitt, C.A.
Blood 129
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5 January 2017
Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.
Duchene, J., Novitzky-Basso, I., Thiriot, A., Casanova-Acebes, M., Bianchini, M., Etheridge, S.L., Hub, E., Nitz, K., Artinger, K., Eller, K., Caamano, J., Ruelicke, T., Moss, P., Megens, R.T.A., von Andrian, U.H., Hidalgo, A., Weber, C. and Rot, A.
Nature Immunology 18
(7): 753-761.
July 2017
17β-estradiol-induced interaction of estrogen receptor α and human atrial essential myosin light chain modulates cardiac contractile function.
Duft, K., Schanz, M., Pham, H., Abdelwahab, A., Schriever, C., Kararigas, G., Dworatzek, E., Davidson, M.M., Regitz-Zagrosek, V., Morano, I. and Mahmoodzadeh, S.
Basic Research in Cardiology 112
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January 2017
Brain iron accumulation in Wilson disease: a post-mortem 7 Tesla MRI - histopathological study.
Dusek, P., Bahn, E., Litwin, T., Jabłonka-Salach, K., Łuciuk, A., Huelnhagen, T., Madai, V.I., Dieringer, M.A., Bulska, E., Knauth, M., Niendorf, T., Sobesky, J., Paul, F., Schneider, S.A., Czlonkowska, A., Brück, W., Wegner, C. and Wuerfel, J.
Neuropathology and Applied Neurobiology 43
(6): 514-532.
October 2017
Cell dynamics underlying oriented growth of the Drosophila wing imaginal disc.
Dye, N.A., Popović, M., Spannl, S., Etournay, R., Kainmüller, D., Ghosh, S., Myers, E.W., Jülicher, F. and Eaton, S.
Development 144
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1 December 2017
Pathogen-reactive T helper cell analysis in the pig.
Ebner, F., Schwiertz, P., Steinfelder, S., Pieper, R., Zentek, J., Schütze, N., Baums, C.G., Alber, G., Geldhof, P. and Hartmann, S.
Frontiers in Immunology 8
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17 May 2017
LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.
Ediger, B.N., Lim, H.W., Juliana, C., Groff, D.N., Williams, L.T., Dominguez, G., Liu, J.H., Taylor, B.L., Walp, E.R., Kameswaran, V., Yang, J., Liu, C., Hunter, C.S., Kaestner, K.H., Naji, A., Li, C., Sander, M., Stein, R., Sussel, L., Won, K.J., May, C.L. and Stoffers, D.A.
Journal of Clinical Investigation 127
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3 January 2017
Specific uptake mechanisms of well-tolerated thermoresponsive polyglycerol-based nanogels in antigen-presenting cells of the skin.
Edlich, Alexander, Gerecke, C., Giulbudagian, M., Neumann, F., Hedtrich, S., Schäfer-Korting, M., Ma, N., Calderon, M. and Kleuser, B.
European Journal of Pharmaceutics and Biopharmaceutics 116
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July 2017
Drug resistance mechanisms in colorectal cancer dissected with cell type-specific dynamic logic models.
Eduati, F., Doldan-Martelli, V., Klinger, B., Cokelaer, T., Sieber, A., Kogera, F., Dorel, M., Garnett, M.J., Blüthgen, N. and Saez-Rodriguez, J.
Cancer Research 77
(12): 3364-3375.
15 June 2017
De novo mutations in SLC25A24 cause a craniosynostosis syndrome with hypertrichosis, progeroid appearance, and mitochondrial dysfunction.
Ehmke, N., Graul-Neumann, L., Smorag, L., Koenig, R., Segebrecht, L., Magoulas, P., Scaglia, F., Kilic, E., Hennig, A.F., Adolphs, N., Saha, N., Fauler, B., Kalscheuer, V.M., Hennig, F., Altmüller, J., Netzer, C., Thiele, H., Nürnberg, P., Yigit, G., Jäger, M., Hecht, J., Krüger, U., Mielke, T., Krawitz, P.M., Horn, D., Schuelke, M., Mundlos, S., Bacino, C.A., Bonnen, P.E., Wollnik, B., Fischer-Zirnsak, B. and Kornak, U.
American Journal of Human Genetics 101
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2 November 2017
Increased placental sFlt-1 but unchanged PlGF expression in late-onset preeclampsia.
Ehrlich, L., Hoeller, A., Golic, M., Herse, F., Perschel, F.H., Henrich, W., Dechend, R., Huppertz, B. and Verlohren, S.
Hypertension in Pregnancy 36
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May 2017
Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
Eichenauer, D.A., Plütschow, A., Kreissl, S., Sökler, M., Hellmuth, J.C., Meissner, J., Mathas, S., Topp, M.S., Behringer, K., Klapper, W., Kuhnert, G., Dietlein, M., Kobe, C., Fuchs, M., Diehl, V., Engert, A. and Borchmann, P.
Lancet Oncology 18
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December 2017
In colon epithelia, Clostridium perfringens enterotoxin causes focal leaks by targeting claudins which are apically accessible due to tight junction derangement.
Eichner, M., Augustin, C., Fromm, A., Piontek, A., Walther, W., Buecker, R., Fromm, M., Krause, G., Schulzke, J.D., Guenzel, D. and Piontek, J.
Journal of Infectious Diseases 217
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27 December 2017
The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
El-Athman, R., Genov, N.N., Mazuch, J., Zhang, K., Yu, Y., Fuhr, L., Abreu, M., Li, Y., Wallach, T., Kramer, A., Schmitt, C.A. and Relógio, A.
PLoS Biology 15
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7 December 2017
Sugar metabolism of the first thermophilic planctomycete thermogutta terrifontis: comparative genomic and transcriptomic approaches.
Elcheninov, A.G., Menzel, P., Gudbergsdottir, S.R., Slesarev, A.I., Kadnikov, V.V., Krogh, A., Bonch-Osmolovskaya, E.A., Peng, X. and Kublanov, I.V.
Frontiers in Microbiology 8
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2 November 2017
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Elling, U., Wimmer, R.A., Leibbrandt, A., Burkard, T., Michlits, G., Leopoldi, A., Micheler, T., Abdeen, D., Zhuk, S., Aspalter, I.M., Handl, C., Liebergesell, J., Hubmann, M., Husa, A.M., Kinzer, M., Schuller, N., Wetzel, E., van de Loo, N., Martinez, J.A.Z., Estoppey, D., Riedl, R., Yang, F., Fu, B., Dechat, T., Ivics, Z., Agu, C.A., Bell, O., Blaas, D., Gerhardt, H., Hoepfner, D., Stark, A. and Penninger, J.M.
Nature 550
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5 October 2017
Systemic and tissue-specific effects of aliskiren on the RAAS and carbohydrate/lipid metabolism in obese patients with hypertension.
Engeli, S., May, M., Nussberger, J., Danser, A.H.J., Dole, W.P., Prescott, M.F., Dahlke, M., Stitah, S., Pal, P., Boschmann, M. and Jordan, J.
Journal of the American Society of Hypertension 11
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August 2017
Anti-diabetic effect of the ethyl acetate fraction of Clerodendrum volubile: protocatechuic acid suppresses phagocytic oxidative burst and modulates inflammatory cytokines.
Erukainure, O.L., Hafizur, R.M., Choudhary, M.I., Adhikari, A., Mesaik, A.M., Atolani, O., Banerjee, P., Preissner, R., Muhammad, A. and Islam, M.S.
Biomedicine & Pharmacotherapy 86
: 307-315.
February 2017
Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.
Espinosa-Medina, I., Jevans, B., Boismoreau, F., Chettouh, Z., Enomoto, H., Müller, T., Birchmeier, C., Burns, Alan J and Brunet, J.F.
Proceedings of the National Academy of Sciences of the United States of America 114
(45): 11980-11985.
7 November 2017
Parvalbumin-expressing GABAergic neurons in primary motor cortex signal reaching.
Estebanez, L., Hoffmann, D., Voigt, B.C. and Poulet, J.F.A.
Cell Reports 20
(2): 308-318.
11 July 2017
Caloric restriction is more efficient than physical exercise to protect from cisplatin nephrotoxicity via PPAR-alpha activation.
Estrela, G.R., Wasinski, F., Batista, R.O., Hiyane, M.I., Felizardo, R.J.F., Cunha, F., de Almeida, D.C., Malheiros, D.M.A.C., Camara, N.O.S., Barros, C.C., Bader, M. and Araujo, R.C.
Frontiers in Physiology 8
: 116.
2 March 2017
MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells.
Estrela, G.R., Wasinski, F., Felizardo, R.J.F., Souza, L.L., Camara, N.O.S., Bader, M. and Araujo, R.C.
Molecular and Cellular Biochemistry 428
(1): 101-108.
April 2017
Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets.
Eulenberg-Gustavus, C., Bähring, S., Maass, P., Luft, F.C. and Kettritz, R.
Journal of Experimental Medicine 214
(7): 2089-2101.
3 July 2017
Detecting markers of therapy-induced senescence in cancer cells.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1534
: 41-52.
2017
Imaging activity-dependent signaling dynamics at the neuronal synapse using FRET-based biosensors.
Farsi, Z. and Woehler, A.
Methods in Molecular Biology 1538
: 261-275.
2017
Vitamin D supplementation reduces some AT1-AA induced downstream targets implicated in preeclampsia including hypertension.
Faulkner, J.L., Amaral, L.M., Cornelius, D.C., Cunningham, M.W., Ibrahim, T., Heep, A., Campbell, N., Usry, N., Wallace, K., Herse, F., Dechend, R. and LaMarca, B.D.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 312
(1): R125-R131.
1 January 2017
Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination.
Fazal, S.V., Gomez-Sanchez, J.A., Wagstaff, L.J., Musner, N., Otto, G., Janz, M., Mirsky, R. and Jessen, K.R.
Journal of Neuroscience 37
(50): 12297-12313.
13 December 2017
A TUBB6 mutation is associated with autosomal dominant non-progressive congenital facial palsy, bilateral ptosis and velopharyngeal dysfunction.
Fazeli, W., Herkenrath, P., Stiller, B., Neugebauer, A., Fricke, J., Lang-Roth, R., Nürnberg, G., Thoenes, M., Becker, J., Altmüller, J., Volk, A.E., Kubisch, C. and Heller, R.
Human Molecular Genetics 26
(20): 4055-4066.
15 October 2017
Diabetes is associated with risk of postoperative cognitive dysfunction: a meta-analysis.
Feinkohl, I., Winterer, G. and Pischon, T.
Diabetes/Metabolism Research and Reviews 33
(5): e2884.
July 2017
Cognitive reserve and the risk of postoperative cognitive dysfunction: a systematic review and meta-analysis.
Feinkohl, I., Winterer, G., Spies, C.D. and Pischon, T.
Deutsches Aerzteblatt International 114
(7): 110-107.
17 February 2017
Glucagon-producing cells are increased in Mas-deficient mice.
Felix Braga, J., Ravizzoni Dartora, D., Alenina, N., Bader, M. and Santos, R.A.S.
Endocrine Connections 6
(1): 27-32.
January 2017
Insulin regulates astrocytic glucose handling through cooperation with IGF-I.
Fernandez, A.M., Hernandez-Garzón, E., Perez-Domper, P., Perez-Alvarez, A., Mederos, S., Matsui, T., Santi, A., Trueba-Saiz, A., Garcia-Guerra, L., Pose-Utrilla, J., Fielitz, J., Olson, E.N., Fernandez de la Rosa, R., Garcia Garcia, L., Pozo, M.A., Iglesias, T., Araque, A., Soya, H., Perea, G., Martin, E.D. and Torres Aleman, I.
Diabetes 66
(1): 64-74.
January 2017
RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.
Ferrai, C., Torlai Triglia, E., Risner-Janiczek, J.R., Rito, T., Rackham, O.J.L., De Santiago, I., Kukalev, A., Nicodemi, M., Akalin, A., Li, M., Ungless, M.A. and Pombo, A.
Molecular Systems Biology 13
(10): 946.
16 October 2017
A chemical disruptor of the ClpX chaperone complex attenuates the virulence of multidrug-resistant Staphylococcus aureus.
Fetzer, C., Korotkov, V.S., Thänert, R., Lee, K.M., Neuenschwander, M., von Kries, J.P., Medina, E. and Sieber, S.A.
Angewandte Chemie International Edition 56
(49): 15746-15750.
4 December 2017
Animal models for personalized treatment options.
Fichtner, I., Klinghammer, K., Behrens, D., Flechsig, S., Rolff, J., Becker, M., Wulf-Goldenberg, A., Stecklum, M., Rivera, M., Brzezicha, B., Jandrig, B. and Hoffmann, J.
International Journal of Clinical Pharmacology and Therapeutics 55
(8): 698-700.
August 2017
Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example.
Fingleton, B., Lange, K., Caldwell, B. and Bankaitis, K.V.
Clinical and Experimental Metastasis 34
(8): 443-447.
December 2017
Evaluation of cognitive deficits and structural hippocampal damage in encephalitis with leucine-rich, glioma-inactivated 1 antibodies.
Finke, C., Prüss, H., Heine, J., Reuter, S., Kopp, U.A., Wegner, F., Then Bergh, F., Koch, S., Jansen, O., Münte, T., Deuschl, G., Ruprecht, K., Stöcker, W., Wandinger, K.P., Paul, F. and Bartsch, T.
JAMA Neurology 74
(1): 50-59.
January 2017
Immunomodulatory molecules in renal cell cancer: CD80 and CD86 are expressed on tumor cells.
Flörcken, A., Johannsen, M., Nguyen-Hoai, T., Gerhardt, A., Miller, K., Dörken, B., Pezzutto, A., Westermann, J. and Jöhrens, K.
International Journal of Clinical and Experimental Pathology 10
(2): 1443-1454.
15 February 2017
Phenotype of antigen unexperienced T(H) cells in the inflamed central nervous system in experimental autoimmune encephalomyelitis.
Franck, S., Paterka, M., Birkenstock, J., Zipp, F., Siffrin, V. and Witsch, E.
Journal of Neuroimmune Pharmacology 12
(2): 305-313.
June 2017
Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer.
Francy, C.A., Clinton, R.W., Froehlich, C., Murphy, C. and Mears, J.A.
Scientific Reports 7
(1): 10744.
6 September 2017
Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Frischauf, I., Litviňuková, M., Schober, R., Zayats, V., Svobodova, B., Bonhenry, D., Lunz, V., Cappello, S., Tociu, L., Reha, D., Stallinger, A., Hochreiter, A., Pammer, T., Butorac, C., Muik, M., Groschner, K., Bogeski, I., Ettrich, R.H., Romanin, C. and Schindl, R.
Science Signaling 10
(507): eaao0358.
28 November 2017
Long-term PEDF release in rat iris and retinal epithelial cells after Sleeping Beauty transposon-mediated gene delivery.
Garcia-Garcia, L., Recalde, S., Hernandez, M., Bezunartea, J., Rodriguez-Madoz, J.R., Johnen, S., Diarra, S., Marie, C., Izsvák, Z., Ivics, Z., Scherman, D., Kropp, M., Thumann, G., Prosper, F., Fernandez-Robredo, P. and Garcia-Layana, A.
Molecular Therapy - Nucleic Acids 9
: 1-11.
15 December 2017
Biocompatibility and characterization of polyglycerol-based thermoresponsive nanogels designed as novel drug-delivery systems and their intracellular localization in keratinocytes.
Gerecke, C., Edlich, A., Giulbudagian, M., Schumacher, F., Zhang, N., Said, A., Yealland, G., Lohan, S.B., Neumann, F., Meinke, M.C., Ma, N., Calderón, M., Hedtrich, S., Schäfer-Korting, M. and Kleuser, B.
Nanotoxicology 11
(2): 267-277.
March 2017
Precision oncology for acute myeloid leukemia using a knowledge bank approach.
Gerstung, M., Papaemmanuil, E., Martincorena, I., Bullinger, L., Gaidzik, V.I., Paschka, P., Heuser, M., Thol, F., Bolli, N., Ganly, P., Ganser, A., McDermott, U., Döhner, K., Schlenk, R.F., Döhner, H. and Campbell, P.J.
Nature Genetics 49
(3): 332-340.
March 2017
EphrinB2 activation enhances vascular repair mechanisms and reduces brain swelling after mild cerebral ischemia.
Ghori, A., Freimann, F.B., Nieminen-Kelhae, M., Kremenetskaia, I., Gertz, K., Endres, M. and Vajkoczy, P.
Arteriosclerosis Thrombosis and Vascular Biology 37
(5): 867-878.
May 2017
Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis.
Gieß, R.M., Pfuhl, C., Behrens, J.R., Rasche, L., Freitag, E., Khalighy, N., Otto, C., Wuerfel, J., Brandt, A.U., Hofmann, J., Eberspächer, B., Bellmann-Strobl, J., Paul, F. and Ruprecht, K.
PLoS ONE 12
(4): e0175279.
7 April 2017
Antibodies to signaling molecules and receptors in Alzheimer's disease are associated with psychomotor slowing, depression, and poor visuospatial function.
Giil, L.M., Vedeler, C.A., Kristoffersen, E.K., Nordrehaug, J.E., Heidecke, H., Dechend, R., Schulze-Forster, K., Muller, D.N., von Goetze, V.S., Cabral-Marques, O., Riemekasten, G., Vogelsang, P., Nygaard, S., Lund, A. and Aarsland, D.
Journal of Alzheimer's Disease 59
(3): 929-939.
29 July 2017
Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B., Richter, A., Richter, A., Preissner, R., Schulze-Osthoff, K., Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292
(16): 6478-6492.
21 April 2017
A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use.
Gleicher, N., Metzger, J., Croft, G., Kushnir, V.A., Albertini, D.F. and Barad, D.H.
Reproductive Biology and Endocrinology 15
(1): 33.
27 April 2017
Parallel habitat acclimatization is realized by the expression of different genes in two closely related salamander species (genus Salamandra).
Goedbloed, D.J., Czypionka, T., Altmüller, J., Rodriguez, A., Küpfer, E., Segev, O., Blaustein, L., Templeton, A.R., Nolte, A.W. and Steinfartz, S.
Heredity 119
(6): 429-437.
December 2017
Aggregation-induced changes in the chemical exchange saturation transfer (CEST) signals of proteins.
Goerke, S., Milde, K.S., Bukowiecki, R., Kunz, P., Klika, K.D., Wiglenda, T., Mogk, A., Wanker, E.E., Bukau, B., Ladd, M.E., Bachert, P. and Zaiss, M.
NMR in Biomedicine 30
(1): e3665.
January 2017
Neue Entwicklungen auf dem Gebiet der Präeklampsie [New developments in the field of preeclampsia].
Golic, M. and Dechend, R.
Nephrologe 12
(2): 115-120.
March 2017
Late-onset Bartter syndrome type II.
Gollasch, B., Anistan, Y.M., Canaan-Kühl, S. and Gollasch, M.
Clinical Kidney Journal 10
(5): 594-599.
October 2017
RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.
Gottlieb, A., Althoff, K., Grunewald, L., Thor, T., Odersky, A., Schulte, M., Deubzer, H.E., Heukamp, L., Eggert, A., Schramm, A., Schulte, J.H. and Künkele, A.
Oncotarget 8
(17): 27882-27891.
25 April 2017
A gene regulatory network balances neural and mesoderm specification during vertebrate trunk development.
Gouti, M., Delile, J., Stamataki, D., Wymeersch, F.J., Huang, Y., Kleinjung, J., Wilson, V. and Briscoe, J.
Developmental Cell 41
(3): 243-261.
8 May 2017
The complete mitochondrial transcript of the red tail loach Yasuhikotakia modesta as assembled from RNAseq (Teleostei: Botiidae).
Grau, J.H., Hilgers, L., Altmüller, J., Šlechtová, V. and Bohlen, J.
Mitochondrial DNA Part B Resources 2
(1): 46-47.
2 February 2017
Loss of Ptpn11 (Shp2) drives satellite cells into quiescence.
Griger, J., Schneider, R., Lahmann, I., Schöwel, V., Keller, C., Spuler, S., Nazare, M. and Birchmeier, C.
eLife 6
: e21552.
2 May 2017
easyGWAS: a cloud-based platform for comparing the results of genome-wide association studies.
Grimm, D.G., Roqueiro, D., Salomé, P.A., Kleeberger, S., Greshake, B., Zhu, W., Liu, C., Lippert, C., Stegle, O., Schölkopf, B., Weigel, D. and Borgwardt, K.M.
Plant Cell 29
(1): 5-19.
January 2017
Maximum walking speed in multiple sclerosis assessed with visual perceptive computing.
Grobelny, A., Behrens, J.R., Mertens, S., Otte, K., Mansow-Model, S., Krüger, T., Gusho, E., Bellmann-Strobl, J., Paul, F., Brandt, A.U. and Schmitz-Hübsch, T.
PLoS ONE 12
(12): e0189281.
15 December 2017
Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit.
Grosheva, A.S., Zharkov, D.O., Stahl, J., Gopanenko, Al.V., Tupikin, A.E., Kabilov, M.R., Graifer, D.M. and Karpova, G.G.
Nucleic Acids Research 45
(7): 3833-3843.
20 April 2017
The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy.
Grüning, B.A., Fallmann, J., Yusuf, D., Will, S., Erxleben, A., Eggenhofer, F., Houwaart, T., Batut, B., Videm, P., Bagnacani, A., Wolfien, M., Lott, S.C., Hoogstrate, Y., Hess, W.R., Wolkenhauer, O., Hoffmann, S., Akalin, A., Ohler, U., Stadler, P.F. and Backofen, R.
Nucleic Acids Research 45
(W1): W560-W566.
3 July 2017
Technical considerations for the use of CRISPR/Cas9 in hematology research.
Gundry, M.C., Dever, D.P., Yudovich, D., Bauer, D.E., Haas, S., Wilkinson, A.C. and Singbrant, S.
Experimental Hematology 54
: 4-11.
October 2017
Protective function of Ahnak1 in vascular healing after wire injury.
Haase, N., Rüder, C., Haase, H., Kamann, S., Kouno, M., Morano, I., Dechend, R., Zohlnhöfer, D. and Haase, T.
Journal of Vascular Research 54
(3): 131-142.
May 2017
Deep brain stimulation during early adolescence prevents microglial alterations in a model of maternal immune activation.
Hadar, R., Dong, L., Del-Valle-Anton, L., Gueneykaya, D., Voget, M., Edemann-Callesen, H., Schweibold, R., Djodari-Irani, A., Goetz, T., Ewing, S., Kettenmann, H., Wolf, S.A. and Winter, C.
Brain, Behavior and Immunity 63
: 71-80.
7 July 2017
McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.
Hafez, D., Karabacak, A., Krueger, S., Hwang, Y.C., Wang, L.S., Zinzen, R.P. and Ohler, U.
Genome Biology 18
(1): 199.
26 October 2017
Identification of the flotillin-1/2 heterocomplex as a target of autoantibodies in bona fide multiple sclerosis.
Hahn, S., Trendelenburg, G., Scharf, M., Denno, Y., Brakopp, S., Teegen, B., Probst, C., Wandinger, K.P., Buttmann, M., Haarmann, A., Szabados, F., Vom Dahl, M., Kuempfel, T., Eichhorn, P., Gold, H., Paul, F., Jarius, S., Melzer, N., Stöcker, W. and Komorowski, L.
Journal of Neuroinflammation 14
(1): 123.
23 June 2017
Germline mutation status, pathological complete response, and disease-free survival in triple-negative breast cancer: secondary analysis of the GeparSixto randomized clinical trial.
Hahnen, E., Lederer, B., Hauke, J., Loibl, S., Kröber, S., Schneeweiss, A., Denkert, C., Fasching, P.A., Blohmer, J.U., Jackisch, C., Paepke, S., Gerber, B., Kümmel, S., Schem, C., Neidhardt, G., Huober, J., Rhiem, K., Costa, S., Altmüller, J., Hanusch, C., Thiele, H., Müller, V., Nürnberg, P., Karn, T., Nekljudova, V., Untch, M., von Minckwitz, G. and Schmutzler, R.K.
JAMA Oncology 3
(10): 1378-1385.
1 October 2017
Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation.
Hammer, A., Schliep, A., Jörg, S., Haghikia, A., Gold, R., Kleinewietfeld, M., Müller, D.N. and Linker, R.A.
Journal of Neuroinflammation 14
(1): 184.
12 September 2017
3 Tesla (23)Na magnetic resonance imaging during acute kidney injury.
Hammon, M., Grossmann, S., Linz, P., Seuss, H., Hammon, R., Rosenhauer, D., Janka, R., Cavallaro, A., Luft, F.C., Titze, J., Uder, M. and Dahlmann, A.
Academic Radiology 24
(9): 1086-1093.
September 2017
Open source 3D multipurpose measurement system with submillimetre fidelity and first application in magnetic resonance.
Han, H., Moritz, R., Oberacker, E., Waiczies, H., Niendorf, T. and Winter, L.
Scientific Reports 7
(1): 13452.
18 October 2017
A fluorescent RNA forced-intercalation probe as a pan-selective marker for influenza A virus infection.
Haralampiev, I., Schade, M., Chamiolo, J., Jolmes, F., Prisner, S., Witkowski, P.T., Behrent, M., Hövelmann, F., Wolff, T., Seitz, O. and Herrmann, A.
ChemBioChem 18
(16): 1589-1592.
17 August 2017
Paracrine and autocrine regulation of gene expression by Wnt-inhibitor Dickkopf in wild-type and mutant hepatocytes.
Hartung, N., Benary, U., Wolf, J. and Kofahl, B.
BMC Systems Biology 11
(1): 98.
13 October 2017
Structural brain changes are associated with response of negative symptoms to prefrontal repetitive transcranial magnetic stimulation in patients with schizophrenia.
Hasan, A., Wobrock, T., Guse, B., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Cordes, J., Woelwer, W., Musso, F., Winterer, G., Gaebel, W., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Dechent, P., Malchow, B., Castro, M.F.U., Dwyer, D., Cabral, C., Kreuzer, P.M., Poeppl, T.B., Schneider-Axmann, T., Falkai, P. and Koutsouleris, N.
Molecular Psychiatry 22
(6): 857-864.
June 2017
Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
Hasegawa, E., Inafuku, S., Mulki, L., Okunuki, Y., Yanai, R., Smith, K.E., Kim, C.B., Klokman, G., Bielenberg, D.R., Puli, N., Falck, J.R., Husain, D., Miller, J.W., Edin, M.L., Zeldin, D.C., Lee, K.S.S., Hammock, B.D., Schunck, W.H. and Connor, K.M.
Proceedings of the National Academy of Sciences of the United States of America 114
(36): E7545-E7553.
5 September 2017
Investigating the link between MCP-1 A-2518G, RANTES G-403A, CX3CR1 V249I and MTHFR C677T gene polymorphisms and the risk of acute myocardial infarction among Egyptians.
Hashad, I.M., Abdel Rahman, M.F., Alenina, N., Bader, M. and Gad, M.Z.
Meta Gene 11
: 181-188.
February 2017
Branched-chain amino acid catabolism rather than amino acids plasma concentrations is associated with diet-induced changes in insulin resistance in overweight to obese individuals.
Haufe, S., Engeli, S., Kaminski, J., Witt, H., Rein, D., Kamlage, B., Utz, W., Fuhrmann, J.C., Haas, V., Mähler, A., Schulz-Menger, J., Luft, F.C., Boschmann, M. and Jordan, J.
Nutrition Metabolism and Cardiovascular Diseases 27
(10): 858-864.
October 2017
NHE1 expression at wound margins increases time-dependently during physiological healing.
Haverkampf, S., Heider, J., Weiß, K.T., Haubner, F., Ettl, T., Schreml, J., Hedtrich, S., von Süßkind-Schwendi, M., Berneburg, M., Karrer, S., Dissemond, J. and Schreml, S.
Experimental dermatology 26
(2): 124-126.
February 2017
Epigenetic mechanism of FMR1 inactivation in Fragile X syndrome.
Hecht, M., Tabib, A., Kahan, T., Orlanski, S., Gropp, M., Tabach, Y., Yanuka, O., Benvenisty, N., Keshet, I. and Cedar, H.
International Journal of Developmental Biology 61
(3-5): 285-292.
2017
What should a person with relapsing-remitting multiple sclerosis know? - Focus group and survey data of a risk knowledge questionnaire (RIKNO 2.0).
Heesen, C., Pöttgen, J., Rahn, A.C., Liethmann, K., Kasper, J., Vahter, L., Drulovic, J., Van Nunen, A., Wilkie, D., Beckmann, Y., Paul, F., Köpke, S., Giordano, A. and Solari, A.
Multiple Sclerosis and Related Disorders 18
: 186-195.
November 2017
Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants.
Hehlmann, R., Lauseker, M., Saußele, S., Pfirrmann, M., Krause, S., Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Heim, D., Brümmendorf, T.H., Fabarius, A., Haferlach, C., Schlegelberger, B., Müller, M.C., Jeromin, S., Proetel, U., Kohlbrenner, K., Voskanyan, A., Rinaldetti, S., Seifarth, W., Spieß, B., Balleisen, L., Goebeler, M.C., Hänel, M., Ho, A., Dengler, J., Falge, C., Kanz, L., Kremers, S., Burchert, A., Kneba, M., Stegelmann, F., Köhne, C.A., Lindemann, H.W., Waller, C.F., Pfreundschuh, M., Spiekermann, K., Berdel, W.E., Müller, L., Edinger, M., Mayer, J., Beelen, D.W., Bentz, M., Link, H., Hertenstein, B., Fuchs, R., Wernli, M., Schlegel, F., Schlag, R., de Wit, M., Trümper, L., Hebart, H., Hahn, M., Thomalla, J., Scheid, C., Schafhausen, P., Verbeek, W., Eckart, M.J., Gassmann, W., Pezzutto, A., Schenk, M., Brossart, P., Geer, T., Bildat, S., Schäfer, E., Hochhaus, A. and Hasford, J.
Leukemia 31
(11): 2398-2406.
November 2017
Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Heidenreich, S., Witte, N., Weber, P., Goehring, I., Tolkachov, A., von Loeffelholz, C., Döcke, S., Bauer, M., Stockmann, M., Pfeiffer, A.F.H., Birkenfeld, A.L., Pietzke, M., Kempa, S., Muenzner, M. and Schupp, M.
Nature Communications 8
(1): 384.
30 August 2017
Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.
Heinig, M., Adriaens, M.E., Schafer, S., van Deutekom, H.W.M., Lodder, E.M., Ware, J.S., Schneider, V., Felkin, L.E., Creemers, E.E., Meder, B., Katus, H.A., Rühle, F., Stoll, M., Cambien, F., Villard, E., Charron, P., Varro, A., Bishopric, N.H., George, A.L., Dos Remedios, C., Moreno-Moral, A., Pesce, F., Bauerfeind, A., Rüschendorf, F., Rintisch, C., Petretto, E., Barton, P.J., Cook, S.A., Pinto, Y.M., Bezzina, C.R. and Hubner, N.
Genome Biology 18
(1): 170.
14 September 2017
ssHMM: extracting intuitive sequence-structure motifs from high-throughput RNA-binding protein data.
Heller, D., Krestel, R., Ohler, U., Vingron, M. and Marsico, A.
Nucleic Acids Research 45
(19): 11004-11018.
2 November 2017
Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation.
Hemmati, P.G., Vuong, L.G., Terwey, T.H., Jehn, C.F., Le Coutre, P., Penack, O., Na, I.K., Dörken, B. and Arnold, R.
European Journal of Haematology 98
(2): 160-168.
February 2017
Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative.
Hendriks, H.R., Govaerts, A.S., Fichtner, I., Burtles, S., Westwell, A.D. and Peters, G.J.
British Journal of Cancer 117
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11 July 2017
Prenatal mechanistic target of rapamycin complex 1 (mTORC1) inhibition by rapamycin treatment of pregnant mice causes intrauterine growth restriction and alters postnatal cardiac growth, morphology, and function.
Hennig, M., Fiedler, S., Jux, C., Thierfelder, L. and Drenckhahn, J.D.
Journal of the American Heart Association 6
(8): e005506.
4 August 2017
The ClC-K2 chloride channel is critical for salt handling in the distal nephron.
Hennings, J.C., Andrini, O., Picard, N., Paulais, M., Huebner, A.K., Lopez Cayuqueo, I.K., Bignon, Y., Keck, M., Cornière, N., Böhm, D., Jentsch, T.J., Chambrey, R., Teulon, J., Hübner, C.A. and Eladari, D.
Journal of the American Society of Nephrology 28
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January 2017
PGBD5 promotes site-specific oncogenic mutations in human tumors.
Henssen, A.G., Koche, R., Zhuang, J., Jiang, E., Reed, C., Eisenberg, A., Still, E., MacArthur, I.C., Rodriguez-Fos, E., Gonzalez, S., Puiggròs, M., Blackford, A.N., Mason, C.E., de Stanchina, E., Gönen, M., Emde, A.K., Shah, M., Arora, K., Reeves, C., Socci, N.D., Perlman, E., Antonescu, C.R., Roberts, C.W.M., Steen, H., Mullen, E., Jackson, S.P., Torrents, D., Weng, Z., Armstrong, S.A. and Kentsis, A.
Nature Genetics 49
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July 2017
Targeting tachykinin receptors in neuroblastoma.
Henssen, A.G., Odersky, A., Szymansky, A., Seiler, M., Althoff, K., Beckers, A., Speleman, F., Schäfers, S., De Preter, K., Astrahanseff, K., Struck, J., Schramm, A., Eggert, A., Bergmann, A. and Schulte, J.H.
Oncotarget 8
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3 January 2017
Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.
Henssen, A.G., Reed, C., Jiang, E., Garcia, H.D., von Stebut, J., MacArthur, I.C., Hundsdoerfer, P., Kim, J.H., de Stanchina, E., Kuwahara, Y., Hosoi, H., Ganem, N.J., Dela Cruz, F., Kung, A.L., Schulte, J.H., Petrini, J.H. and Kentsis, A.
Science Translational Medicine 9
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1 November 2017
Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells.
Herce, H.D., Schumacher, D., Schneider, A.F.L., Ludwig, A.K., Mann, F.A., Fillies, M., Kasper, M.-A., Reinke, S., Krause, E., Leonhardt, H., Cardoso, M.C. and Hackenberger, C.P.R.
Nature Chemistry 9
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August 2017
Frequency of exercise-induced ST-T-segment deviations and cardiac arrhythmias in recreational endurance athletes during a marathon race: results of the prospective observational Berlin Beat of Running study.
Herm, J., Toepper, A., Wutzler, A., Kunze, C., Kruell, M., Brechtel, L., Lock, J., Fiebach, J.B., Heuschmann, P.U., Haverkamp, W., Endres, M., Jungehulsing, G.J. and Haeusler, K.G.
BMJ Open 7
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3 August 2017
Genetic identification of a hindbrain nucleus essential for innate vocalization.
Hernandez-Miranda, L.R., Ruffault, P.L., Bouvier, J.C., Murray, A.J., Morin-Surun, M.P., Zampieri, N., Cholewa-Waclaw, J.B., Ey, E., Brunet, J.F., Champagnat, J., Fortin, G. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 114
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25 July 2017
RNA-seq based transcriptome analysis of the type I interferon host response upon vaccinia virus infection of mouse cells.
Hernáez, B., Alonso, G., Alonso-Lobo, J.M., Rastrojo, A., Fischer, C., Sauer, S., Aguado, B. and Alcamí, A.
Journal of Immunology Research 2017
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9 February 2017
CTLA4 promotes Tyk2-STAT3 dependent B-cell oncogenecity.
Herrmann, A., Lahtz, C., Nagao, T., Song, J.Y., Chan, W.C., Lee, H., Yue, C., Look, T., Muelfarth, R., Li, W., Jenkins, K., Williams, J., Budde, L.E., Forman, S.J., Kwak, L.W., Blankenstein, T. and Yu, H.
Cancer Research 77
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15 September 2017
Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair.
Herzig, J.K., Bullinger, L., Tasdogan, A., Zimmermann, P., Schlegel, M., Teleanu, V., Weber, D., Rücker, F.G., Paschka, P., Dolnik, A., Schneider, E., Kuchenbauer, F., Heidel, F.H., Buske, C., Döhner, H., Döhner, K. and Gaidzik, V.I.
Oncotarget 8
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10 November 2017
Partitioned learning of deep Boltzmann machines for SNP data.
Hess, M., Lenz, S., Blätte, T.J., Bullinger, L. and Binder, H.
Bioinformatics 33
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October 2017
Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
Hessenberger, M., Zerbes, R.M., Rampelt, H., Kunz, S., Xavier, A.H., Purfürst, B., Lilie, H., Pfanner, N., van der Laan, M. and Daumke, O.
Nature Communications 8
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31 May 2017
Immunoproteasome subunit β5i/LMP7-deficiency in atherosclerosis.
Hewing, B., Ludwig, A., Dan, C., Poetzsch, M., Hannemann, C., Petry, A., Lauer, D., Görlach, A., Kaschina, E., Müller, D.N., Baumann, G., Stangl, V., Stangl, K. and Wilck, N.
Scientific Reports 7
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17 October 2017
Evaluating the impact of genetic and epigenetic aberrations on survival and response in acute myeloid leukemia patients receiving epigenetic therapy.
Hiller, J.K., Schmoor, C., Gaidzik, V.I., Schmidt-Salzmann, C., Yalcin, A., Abdelkarim, M., Blagitko-Dorfs, N., Döhner, K., Bullinger, L., Duyster, J., Lübbert, M. and Hackanson, B.
Annals of Hematology 96
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April 2017
Small molecules targeting human N-acetylmannosamine kinase.
Hinderlich, S., Neuenschwander, M., Wratil, P.R., Oder, A., Lisurek, M., Nguyen, L.D., von Kries, J.P. and Hackenberger, C.P.R.
ChemBioChem 18
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4 July 2017
Systemic virus infections differentially modulate cell cycle state and functionality of long-term hematopoietic stem cells in vivo.
Hirche, C., Frenz, T., Haas, S.F., Döring, M., Borst, K., Tegtmeyer, P.K., Brizic, I., Jordan, S., Keyser, K., Chhatbar, C., Pronk, E., Lin, S., Messerle, M., Jonjic, S., Falk, C.S., Trumpp, A., Essers, M.A.G. and Kalinke, U.
Cell Reports 19
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13 June 2017
Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia.
Hirsch, S., Blätte, T.J., Grasedieck, S., Cocciardi, S., Rouhi, A., Jongen-Lavrencic, M., Paschka, P., Krönke, J., Gaidzik, V.I., Döhner, H., Schlenk, R.F., Kuchenbauer, F., Döhner, K., Dolnik, A. and Bullinger, L.
Haematologica 102
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December 2017
Placental expression of sFlt-1 and PlGF in early preeclampsia vs. early IUGR vs. age-matched healthy pregnancies.
Hoeller, A., Ehrlich, L., Golic, M., Herse, F., Perschel, F.H., Siwetz, M., Henrich, W., Dechend, R., Huppertz, B. and Verlohren, S.
Hypertension in Pregnancy 36
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May 2017
Response evaluation in head and neck oncology: definition and prediction.
Hoffmann, T.K., Schuler, P.J., Laban, S., Grässlin, R., Beer, M., Beer, A.J., Friebe-Hoffmann, U., Bullinger, L., Möller, P. and Wiegel, T.
ORL 79
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February 2017
Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS).
Horpaopan, S., Kirfel, J., Peters, S., Kloth, M., Hüneburg, R., Altmüller, J., Drichel, D., Odenthal, M., Kristiansen, G., Strassburg, C., Nattermann, J., Hoffmann, P., Nürnberg, P., Büttner, R., Thiele, H., Kahl, P., Spier, I. and Aretz, S.
Hereditary Cancer in Clinical Practice 15
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29 November 2017
Role of Müller cell cytochrome P450 2c44 in murine retinal angiogenesis.
Hu, J., Geyer, A., Dziumbla, S., Awwad, K., Zeldin, D.C., Schunck, W.H., Popp, R., Frömel, T. and Fleming, I.
Prostaglandins & Other Lipid Mediators 133
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November 2017
Signatures of personality on dense 3D facial images.
Hu, S., Xiong, J., Fu, P., Qiao, L., Tan, J., Jin, L. and Tang, K.
Scientific Reports 7
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March 2017
Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.
Huang, K.L., Li, S., Mertins, P., Cao, S., Gunawardena, H.P., Ruggles, K.V., Mani, D.R., Clauser, K.R., Tanioka, M., Usary, J., Kavuri, S.M., Xie, L., Yoon, C., Qiao, J.W., Wrobel, J., Wyczalkowski, M.A., Erdmann-Gilmore, P., Snider, J.E., Hoog, J., Singh, P., Niu, B., Guo, Z., Sun, S.Q., Sanati, S., Kawaler, E., Wang, X., Scott, A., Ye, K., McLellan, M.D., Wendl, M.C., Malovannaya, A., Held, J.M., Gillette, M.A., Fenyö, D., Kinsinger, C.R., Mesri, M., Rodriguez, H., Davies, S.R., Perou, C.M., Ma, C., Townsend, R.R., Chen, X., Carr, S.A., Ellis, M.J. and Ding, L.
Nature Communications 8
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28 March 2017
Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy.
Huang, N., Kny, M., Riediger, F., Busch, K., Schmidt, S., Luft, F.C., Slevogt, H. and Fielitz, J.
Intensive Care Medicine Experimental 5
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17 January 2017
SORLA attenuates EphA4 signaling and amyloid, β-induced neurodegeneration.
Huang, T.Y., Zhao, Y., Jiang, L.L., Li, X., Liu, Y., Sun, Y., Piña-Crespo, J.C., Zhu, B., Masliah, E., Willnow, T.E., Pasquale, E.B. and Xu, H.
Journal of Experimental Medicine 214
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4 December 2017
Myocardial T(2)(*) mapping at ultrahigh magnetic fields: in vivo myocardial tissue characterization and assessment of cardiac physiology with magnetic resonance imaging.
Huelnhagen, T., Flemming, B., Seeliger, E., Schulz-Menger, J. and Niendorf, T.
Current Directions in Biomedical Engineering 3
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September 2017
Myocardial effective transverse relaxation time T(2)* correlates with left ventricular wall thickness: a 7.0 T MRI study.
Huelnhagen, T., Hezel, F., Serradas Duarte, T., Pohlmann, A., Oezerdem, C., Flemming, B., Seeliger, E., Prothmann, M., Schulz-Menger, J. and Niendorf, T.
Magnetic Resonance in Medicine 77
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June 2017
Myocardial T(2)* mapping with ultrahigh field magnetic resonance: physics and frontier applications.
Huelnhagen, T., Paul, K., Ku, M.C., Serradas Duarte, T. and Niendorf, T.
Frontiers in Physics 5
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June 2017
Fast genome-wide functional annotation through orthology assignment by eggNOG-mapper.
Huerta-Cepas, J., Forslund, K., Coelho, L.P., Szklarczyk, D., Jensen, L.J., von Mering, C. and Bork, P.
Molecular Biology and Evolution 34
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1 August 2017
Activating de novo mutations in NFE2L2 encoding NRF2 cause a multisystem disorder.
Huppke, P., Weissbach, S., Church, J.A., Schnur, R., Krusen, M., Dreha-Kulaczewski, S., Kühn-Velten, W.N., Wolf, A., Huppke, B., Millan, F., Begtrup, A., Almusafri, F., Thiele, H., Altmüller, J., Nürnberg, P., Müller, M. and Gärtner, J.
Nature Communications 8
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10 October 2017
INSERT: A novel clinical scanner for simultaneous SPECT/MRI brain studies.
Hutton, B.F., Erlandsson, K., Salvado, D., Occhipinti, M., Papp, Z., Tolgyesi, B., Willems, J., Piemonte, C., Carminati, M., Bukki, T., Legrady, G., Kuehne, A., Nyitrai, Z., Niendorf, T., Van Mullekom, P., Waiczies, H., Nagy, K., De Francesco, I., Mathe, D., Ottobrini, L., Short, S.C. and Fiorini, C.
IEEE Nuclear Science Symposium and Medical Imaging Conference
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2017
Pilot study of psychiatric and social aspects of children and adolescents with fragile X syndrome [Pilotstudie zu psychiatrischen und sozialen Aspekten bei Kindern und Jugendlichen mit Fragilem-X-Syndrom (FRX)].
Häßler, F., Gaese, F., Colla, M., Huss, M., Kretschmar, C., Brinkman, M., Peters, H., Elstner, S., Weirich, S. and Pittrow, D.
Zeitschrift fuer Kinder- und Jugendpsychiatrie und Psychotherapie 45
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March 2017
Synapsin-antibodies in psychiatric and neurological disorders: prevalence and clinical findings.
Höltje, M., Mertens, R., Schou, M.B., Saether, S.G., Kochova, E., Jarius, S., Prüss, H., Komorowski, L., Probst, C., Paul, F., Bellmann-Strobl, J., Gitler, D., Benfenati, F., Piepgras, J., Ahnert-Hilger, G. and Ruprecht, K.
Brain Behavior and Immunity 66
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November 2017
Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy.
Ibrahim, T., Przybyl, L., Harmon, A.C., Amaral, L.M., Faulkner, J.L., Cornelius, D., Cunningham, M.W., Hünig, T., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Reproductive Immunology 78
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November 2017
A synthetic biology approach to probing nucleosome symmetry.
Ichikawa, Y., Connelly, C.F., Appleboim, A., Miller, T.C., Jacobi, H., Abshiru, N.A., Chou, H.J., Chen, Y., Sharma, U., Zheng, Y., Thomas, P.M., Chen, H.V., Bajaj, V., Müller, C.W., Kelleher, N.L., Friedman, N., Bolon, D.N.A., Rando, O.J. and Kaufman, P.D.
eLife 6
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12 September 2017
Neuronal chemosensation and osmotic stress response converge in the regulation of aqp-8 in C. elegans.
Igual Gil, C., Jarius, M., von Kries, J.P. and Rohlfing, A.K.
Frontiers in Physiology 8
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9 June 2017
SIRT1 regulates macrophage self-renewal.
Imperatore, F., Maurizio, J., Vargas Aguilar, S., Busch, C.J., Favret, J., Kowenz-Leutz, E., Cathou, W., Gentek, R., Perrin, P., Leutz, A., Berruyer, C. and Sieweke, M.H.
EMBO Journal 36
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15 August 2017
Compound annotation in liquid chromatography/high-resolution mass spectrometry based metabolomics: robust adduct ion determination as a prerequisite to structure prediction in electrospray ionization mass spectra.
Jaeger, C., Méret, M., Schmitt, C.A. and Lisec, J.
Rapid Communications in Mass Spectrometry 31
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15 August 2017
24 h-accelerometry in epidemiological studies : automated detection of non-wear time in comparison to diary information.
Jaeschke, L., Luzak, A., Steinbrecher, A., Jeran, S., Ferland, M., Linkohr, B., Schulz, H. and Pischon, T.
Scientific Reports 7
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22 May 2017
Tracking the evolution of non-small-cell lung cancer.
Jamal-Hanjani, M., Wilson, G.A., McGranahan, N., Birkbak, N.J., Watkins, T.B.K., Veeriah, S., Shafi, S., Johnson, D.H., Mitter, R., Rosenthal, R., Salm, M., Horswell, S., Escudero, M., Matthews, N., Rowan, A., Chambers, T., Moore, D.A., Turajlic, S., Xu, H., Lee, S.-M., Forster, M.D., Ahmad, T., Hiley, C.T., Abbosh, C., Falzon, M., Borg, E., Marafioti, T., Lawrence, D., Hayward, M., Kolvekar, S., Panagiotopoulos, N., Janes, S.M., Thakrar, R., Ahmed, A., Blackhall, F., Summers, Y., Shah, R., Joseph, L., Quinn, A.M., Crosbie, P.A., Naidu, B., Middleton, G., Langman, G., Trotter, S., Nicolson, M., Remmen, H., Kerr, K., Chetty, M., Gomersall, L., Fennell, D.A., Nakas, A., Rathinam, S., Anand, G., Khan, S., Russell, P., Ezhil, V., Ismail, B., Irvin-Sellers, M., Prakash, V., Lester, J.F., Kornaszewska, M., Attanoos, R., Adams, H., Davies, H., Dentro, S., Taniere, P., O'Sullivan, B., Lowe, H.L., Hartley, J.A., Iles, N., Bell, H., Ngai, Y., Shaw, J.A., Herrero, J., Szallasi, Z., Schwarz, R.F., Stewart, A., Quezada, S.A., Le Quesne, J., Van Loo, P., Dive, C., Hackshaw, A. and Swanton, C.
New England Journal of Medicine 376
(22): 2109-2121.
1 June 2017
Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis.
Jarius, S., König, F.B., Metz, I., Ruprecht, K., Paul, F., Brück, W. and Wildemann, B.
Journal of Neuroinflammation 14
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29 August 2017
Tricellulin is a target of the ubiquitin ligase Itch.
Jennek, S., Mittag, S., Reiche, J., Westphal, J.K., Seelk, S., Dörfel, M.J., Pfirrmann, T., Friedrich, K., Schütz, A., Heinemann, U. and Huber, O.
Annals of the New York Academy of Sciences 1397
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June 2017
Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Jerke, U., Marino, S.F., Daumke, O. and Kettritz, R.
Scientific Reports 7
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27 February 2017
TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression.
Jiang, C., Zhu, Y., Zhou, Z., Gumin, J., Bengtsson, L., Wu, W., Songyang, Z., Lang, F.F. and Lin, X.
Oncogene 36
(20): 2813-2823.
18 May 2017
Metabolic anchor reactions for robust biorefining.
Jouhten, P., Huerta-Cepas, J., Bork, P. and Patil, K.R.
Metabolic Engineering 40
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March 2017
Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.
Juneja, M., Kobelt, D., Walther, W., Voss, C., Smith, J., Specker, E., Neuenschwander, M., Gohlke, B.O., Dahlmann, M., Radetzki, S., Preissner, R., von Kries, J.P., Schlag, P.M. and Stein, U.
PLoS Biology 15
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1 June 2017
A cellular platform for the evaluation of immune checkpoint molecules.
Jutz, S., Hennig, A., Paster, W., Asrak, Ö., Dijanovic, D., Kellner, F., Pickl, W.F., Huppa, J.B., Leitner, J. and Steinberger, P.
Oncotarget 8
(39): 64892-64906.
12 September 2017
Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes.
Jäger, S., Wahl, S., Kröger, J., Sharma, S., Hoffmann, P., Floegel, A., Pischon, T., Prehn, C., Adamski, J., Müller-Nurasyid, M., Waldenberger, M., Strauch, K., Peters, A., Gieger, C., Suhre, K., Grallert, H., Boeing, H., Schulze, M.B. and Meidtner, K.
Scientific Reports 7
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20 July 2017
Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction.
Järve, A., Mühlstedt, S., Qadri, F., Nickl, B., Schulz, H., Hübner, N., Özcelik, C. and Bader, M.
FASEB Journal 31
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February 2017
Development of mouse model systems of germinal center lymphomas.
Kabrani, E. and Sander, S.
Methods in Molecular Biology 1623
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2017
Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T., Friese, C., Arina, A., Idel, C., Briesemeister, D., Rothe, M., Ivanov, A., Szymborska, A., Patone, G., Kunz, S., Sommermeyer, D., Engels, B., Leisegang, M., Textor, A., Fehling, H.J., Fruttiger, M., Lohoff, M., Herrmann, A., Yu, H., Weichselbaum, R., Uckert, W., Hübner, N., Gerhardt, H., Beule, D., Schreiber, H. and Blankenstein, T.
Nature 545
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4 May 2017
Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression.
Kar, G., Kim, J.K., Kolodziejczyk, A.A., Natarajan, K.N., Torlai Triglia, E., Mifsud, B., Elderkin, S., Marioni, J.C., Pombo, A. and Teichmann, S.A.
Nature Communications 8
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26 June 2017
The Drosophila embryo at single-cell transcriptome resolution.
Karaiskos, N., Wahle, P., Alles, J., Boltengagen, A., Ayoub, S., Kipar, C., Kocks, C., Rajewsky, N. and Zinzen, R.P.
Science 358
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13 October 2017
Efferocytosis of pathogen-infected cells.
Karaji, N. and Sattentau, Q.J.
Frontiers in Immunology 8
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22 December 2017
A comprehensive TALEN-based knockout library for generating human induced pluripotent stem cell-based models for cardiovascular diseases.
Karakikes, I., Termglinchan, V., Cepeda, D.A., Lee, J., Diecke, S., Hendel, A., Itzhaki, I., Ameen, M., Shrestha, R., Wu, H., Ma, N., Shao, N.Y., Seeger, T., Woo, N.A., Wilson, K.D., Matsa, E., Porteus, M.H., Sebastiano, V. and Wu, J.C.
Circulation Research 120
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12 May 2017
Identifying ischemic stroke associated with cancer: a multiple model derived from a case-control analysis.
Kassubek, R., Bullinger, L., Kassubek, J., Dreyhaupt, J., Ludolph, A.C., Althaus, K. and Lewerenz, J.
Journal of Neurology 264
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April 2017
mRNA interactome capture in mammalian cells.
Kastelic, N. and Landthaler, M.
Methods 126
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15 August 2017
Anti-aquaporin-4 titer is not predictive of disease course in neuromyelitis optica spectrum disorder: a multicenter cohort study.
Kessler, R.A., Mealy, M.A., Jimenez-Arango, J.A., Quan, C., Paul, F., López, R., Hopkins, S. and Levy, M.
Multiple Sclerosis and Related Disorders 17
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October 2017
A deep intronic CLRN1 (USH3A) founder mutation generates an aberrant exon and underlies severe Usher syndrome on the Arabian Peninsula.
Khan, A.O., Becirovic, E., Betz, C., Neuhaus, C., Altmüller, J., Maria Riedmayr, L., Motameny, S., Nürnberg, G., Nürnberg, P. and Bolz, H.J.
Scientific Reports 7
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3 May 2017
Disruption of the vacuolar-type H(+)-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes.
Kissing, S., Rudnik, S., Damme, M., Luellmann-Rauch, R., Ichihara, A., Kornak, U., Eskelinen, E.L., Jabs, S., Heeren, J., De Brabander, J.K., Haas, A. and Saftig, P.
Autophagy 13
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April 2017
High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
Kitada, K., Daub, S., Zhang, Y., Klein, J. D., Nakano, D., Pedchenko, T., Lantier, L., LaRocque, L.M., Marton, A., Neubert, P., Schröder, A., Rakova, N., Jantsch, J., Dikalova, A.E., Dikalov, S.I., Harrison, D.G., Müller, D.N., Nishiyama, A., Rauh, M., Harris, R. C., Luft, F.C., Wassermann, D.H., Sands, J.M. and Titze, J.
Journal of Clinical Investigation 127
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1 May 2017
Longer-term impact of hemiparetic stroke on skeletal muscle metabolism - a pilot study.
Klaer, J., Mähler, A., Scherbakov, N., Klug, L., von Haehling, S., Boschmann, M. and Doehner, W.
International Journal of Cardiology 230
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1 March 2017
High risk of postpartum relapses in neuromyelitis optica spectrum disorder.
Klawiter, E.C., Bove, R., Elsone, L., Alvarez, E., Borisow, N., Cortez, M., Mateen, F., Mealy, M.A., Sorum, J., Mutch, K., Tobyne, S.M., Ruprecht, K., Buckle, G., Levy, M., Wingerchuk, D., Paul, F., Cross, A.H., Jacobs, A., Chitnis, T. and Weinshenker, B.
Neurology 89
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28 November 2017
Pole-to-Pole connections: similarities between arctic and antarctic microbiomes and their vulnerability to environmental change.
Kleinteich, J., Hildebrand, F., Bahram, M., Voigt, A.Y., Wood, S.A., Jungblut, A.D., Kuepper, F.C., Quesada, A., Camacho, A., Pearce, D.A., Convey, P., Vincent, W.F., Zarfl, C., Bork, P. and Dietrich, D.R.
Frontiers in Ecology and Evolution 5
: 137.
10 November 2017
Gut microbiota differs between children with inflammatory bowel disease and healthy siblings in taxonomic and functional composition: a metagenomic analysis.
Knoll, R.L., Forslund, K., Kultima, J.R., Meyer, C.U., Kullmer, U., Sunagawa, S., Bork, P. and Gehring, S.
American Journal of Physiology Gastrointestinal and Liver Physiology 312
(4): G327-G339.
1 April 2017
Alkaline poly(ethylene glycol)-based hydrogels for a potential use as bioactive wound dressings.
Koehler, J., Verheyen, L., Hedtrich, S., Brandl, F.P. and Goepferich, A.M.
Journal of Biomedical Materials Research Part A 105
(12): 3360-3368.
December 2017
pH-modulating poly(ethylene glycol)/alginate hydrogel dressings for the treatment of chronic wounds.
Koehler, J., Wallmeyer, L., Hedtrich, S., Goepferich, A.M. and Brandl, F.P.
Macromolecular Bioscience 17
(5): 1600369.
May 2017
Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits.
Konigorski, S., Yilmaz, Y.E. and Pischon, T.
PLoS ONE 12
(5): e0178504.
31 May 2017
Alloimmune responses of humanized mice to human pluripotent stem cell therapeutics.
Kooreman, N.G., de Almeida, P.E., Stack, J.P., Nelakanti, R.V., Diecke, S., Shao, N.Y., Swijnenburg, R.J., Sanchez-Freire, V., Matsa, E., Liu, C., Connolly, A.J., Hamming, J.F., Quax, P.H.A., Brehm, M.A., Greiner, D.L., Shultz, L.D. and Wu, J.C.
Cell Reports 20
(8): 1978-1990.
22 August 2017
Na(+) deposition in the fibrotic skin of systemic sclerosis patients detected by (23)Na-magnetic resonance imaging.
Kopp, C., Beyer, C., Linz, P., Dahlmann, A., Hammon, M., Jantsch, J., Neubert, P., Rosenhauer, D., Müller, D.N., Cavallaro, A., Eckardt, K.U., Schett, G., Luft, F.C., Uder, M., Distler, J.H.W. and Titze, J.
Rheumatology 56
(4): 556-560.
1 April 2017
Dynamics and heterogeneity of brain damage in multiple sclerosis.
Kotelnikova, E., Kiani, N.A., Abad, E., Martinez-Lapiscina, E.H., Andorra, M., Zubizarreta, I., Pulido-Valdeolivas, I., Pertsovskaya, I., Alexopoulos, L.G., Olsson, T., Martin, R., Paul, F., Tegnér, J., Garcia-Ojalvo, J. and Villoslada, P.
PLoS Computational Biology 13
(10): e1005757.
26 October 2017
Astrocytic calcium waves signal brain injury to neural stem and progenitor cells.
Kraft, A., Jubal, E.R., von Laer, R., Döring, C., Rocha, A., Grebbin, M., Zenke, M., Kettenmann, H., Stroh, A. and Momma, S.
Stem Cell Reports 8
(3): 701-714.
14 March 2017
IKZF1 expression is a prognostic marker in newly diagnosed standard-risk multiple myeloma treated with lenalidomide and intensive chemotherapy: a study of the German Myeloma Study Group (DSMM).
Krönke, J., Kuchenbauer, F., Kull, M., Teleanu, V., Bullinger, L., Bunjes, D., Greiner, A., Kolmus, S., Köpff, S., Schreder, M., Mügge, L.O., Straka, C., Engelhardt, M., Döhner, H., Einsele, H., Bassermann, F., Bargou, R., Knop, S. and Langer, C.
Leukemia 31
(6): 1363-1367.
June 2017
Subjective and objective assessment of physical activity in multiple sclerosis and their relation to health-related quality of life.
Krüger, T., Behrens, J.R., Grobelny, A., Otte, K., Mansow-Model, S., Kayser, B., Bellmann-Strobl, J., Brandt, A.U., Paul, F. and Schmitz-Hübsch, T.
BMC Neurology 17
(1): 10.
13 January 2017
Placental-specific overexpression of sFlt-1 alters trophoblast differentiation and nutrient transporter expression in an IUGR mouse model.
Kuehnel, E., Kleff, V., Stojanovska, V., Kaiser, S., Waldschuetz, R., Herse, F., Ploesch, T., Winterhager, E. and Gellhaus, A.
Journal of Cellular Biochemistry 118
(6): 1316-1329.
June 2017
Localized irradiation of mouse legs using an image-guided robotic linear accelerator.
Kufeld, M., Escobar, H., Marg, A., Pasemann, D., Budach, V. and Spuler, S.
Annals of Translational Medicine 5
(7): 156.
April 2017
S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.
Kumar, A., Dejanovic, B., Hetsch, F., Semtner, M., Fusca, D., Arjune, S., Santamaria-Araujo, J.A., Winkelmann, A., Ayton, S., Bush, A.I., Kloppenburg, P., Meier, J.C., Schwarz, G. and Belaidi, A.A.
Journal of Clinical Investigation 127
(12): 4365-4378.
1 December 2017
The global cardiovascular magnetic resonance registry (GCMR) of the society for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments.
Kwong, R.Y., Petersen, S.E., Schulz-Menger, J., Arai, A.E., Bingham, S.E., Chen, Y., Choi, Y.L., Cury, R.C., Ferreira, V.M., Flamm, S.D., Steel, K., Bandettini, W.P., Martin, E.T., Nallamshetty, L., Neubauer, S., Raman, S.V., Schelbert, E.B., Valeti, U.S., Cao, J.J., Reichek, N., Young, A.A., Fexon, L., Pivovarov, M., Ferrari, V.A. and Simonetti, O.P.
Journal of Cardiovascular Magnetic Resonance 19
(1): 23.
20 January 2017
Mouse cutaneous melanoma induced by mutant BRaf arises from expansion and dedifferentiation of mature pigmented melanocytes.
Köhler, C., Nittner, D., Rambow, F., Radaelli, E., Stanchi, F., Vandamme, N., Baggiolini, A., Sommer, L., Berx, G., van den Oord, J.J., Gerhardt, H., Blanpain, C. and Marine, J.C.
Cell Stem Cell 21
(5): 679-693.e6.
2 November 2017
Prevalence of impaired kidney function in the German elderly: results from the Berlin Aging Study II (BASE-II).
König, M., Gollasch, M., Demuth, I. and Steinhagen-Thiessen, Elisabeth
Gerontology 63
(3): 201-209.
April 2017
Tomo-seq identifies SOX9 as a key regulator of cardiac fibrosis during ischemic injury.
Lacraz, G.P.A., Junker, J.P., Gladka, M.M., Molenaar, B., Scholman, K.T., Vigil-Garcia, M., Versteeg, D., de Ruiter, H., Vermunt, M.W., Creyghton, M.P., Huibers, M.M.H., de Jonge, N., van Oudenaarden, A. and van Rooij, E.
Circulation 136
(15): 1396-1409.
10 October 2017
A genomic comparison of putative pathogenicity-related gene families in five members of the Ophiostomatales with different lifestyles.
Lah, L., Löber, U., Hsiang, T. and Hartmann, S.
Fungal Biology 121
(3): 234-252.
March 2017
Alzheimer's disease: elevated pigment epithelium-derived factor in the cerebrospinal fluid is mostly of systemic origin.
Lang, V., Zille, M., Infante-Duarte, C., Jarius, S., Jahn, H., Paul, F., Ruprecht, K. and Pina, A.L.
Journal of the Neurological Sciences 375
: 123-128.
15 April 2017
Salt sensitivity of angiogenesis inhibition-induced blood pressure rise: role of interstitial sodium accumulation?
Lankhorst, S., Severs, D., Markó, L., Rakova, N., Titze, J., Müller, D.N., Danser, A.H.J. and van den Meiracker, A.H.
Hypertension 69
(5): 919-926.
May 2017
Purification and characterisation of the yeast plasma membrane ATP binding cassette transporter Pdr11p.
Laub, K.R., Marek, M., Stanchev, L.D., Herrera, S.A., Kanashova, T., Bourmaud, A., Dittmar, G. and Guenther Pomorski, T.
PLoS ONE 12
(9): e0184236.
18 September 2017
Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology.
Le Thanh, P., Meinke, P., Korfali, N., Srsen, V., Robson, M.I., Wehnert, M., Schoser, B., Sewry, C.A. and Schirmer, E.C.
Neuromuscular Disorders 27
(4): 338-351.
April 2017
Ensembles of lasso screening rules.
Lee, S., Görnitz, N., Xing, E.P., Heckerman, D. and Lippert, C.
IEEE Transactions on Pattern Analysis and Machine Intelligence 40
(12): 2841-2852.
24 November 2017
Circ-ZNF609 is a circular RNA that can be translated and functions in myogenesis.
Legnini, I., Di Timoteo, G., Rossi, F., Morlando, M., Briganti, F., Sthandier, O., Fatica, A., Santini, T., Andronache, A., Wade, M., Laneve, P., Rajewsky, N. and Bozzoni, I.
Molecular Cell 66
(1): 22-37.e9.
6 April 2017
Evidence for heterodimerization and functional interaction of the angiotensin Type 2 receptor and the receptor MAS.
Leonhardt, J., Villela, D.C., Teichmann, A., Münter, L.-M., Mayer, M.C., Mardahl, M., Kirsch, S., Namsolleck, P., Lucht, K., Benz, V., Alenina, N., Daniell, N., Horiuchi, M., Iwai, M., Multhaup, G., Schülein, R., Bader, M., Santos, R.A., Unger, T. and Steckelings, U.M.
Hypertension 69
(6): 1128-1135.
June 2017
Cardiac morphofunctional characteristics of transgenic rats with overexpression of the bradykinin B1 receptor in the endothelium.
Levy, R.F., Serra, A.J., Antonio, E.L., dos Santos, L., Bocalini, D.S., Pesquero, J.B., Bader, M., Merino, V.F., de Oliveira, H.A., de Arruda Veiga, E.C., Silva, J.A. and Tucci, P.J.F.
Physiological Research 66
(6): 925-932.
22 September 2017
Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.
Liao, C., Ashley, N., Diot, A., Morten, K., Phadwal, K., Williams, A., Fearnley, I., Rosser, L., Lowndes, J., Fratter, C., Ferguson, D.J.P., Vay, L., Quaghebeur, G., Moroni, I., Bianchi, S., Lamperti, C., Downes, S.M., Sitarz, K.S., Flannery, P.J., Carver, J., Dombi, E., East, D., Laura, M., Reilly, M.M., Mortiboys, H., Prevo, R., Campanella, M., Daniels, M.J., Zeviani, M., Yu-Wai-Man, P., Simon, A.K., Votruba, M. and Poulton, J.
Neurology 88
(2): 131-142.
10 January 2017
Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice.
Lim, C.S., Kim, H., Yu, N.K., Kang, S.J., Kim, T.H., Ko, H.G., Lee, J., Yang, J.E., Ryu, H.H., Park, T., Gim, J., Nam, H.J., Baek, S.H., Wegener, S., Schmitz, D., Boeckers, T.M., Lee, M.G., Kim, E., Lee, J.H., Lee, Y.S. and Kaang, B.K.
Neuropharmacology 112
(Part A): 104-112.
January 2017
Electrocardiographic assessments and cardiac events after fingolimod first dose - a comprehensive monitoring study.
Limmroth, V., Ziemssen, T., Lang, M., Richter, S., Wagner, B., Haas, J., Schmidt, S., Gerbershagen, K., Lassek, C., Klotz, L., Hoffmann, O., Albert, C., Schuh, K., Baier-Ebert, M., Wendt, G., Schieb, H., Hoyer, S., Dechend, R. and Haverkamp, W.
BMC Neurology 17
(1): 11.
18 January 2017
Fusion of SpCas9 to E.coli Rec A protein enhances CRISPR-Cas9 mediated gene knockout in mammalian cells.
Lin, L., Petersen, T.S., Jensen, K.T., Bolund, L., Kühn, R. and Luo, Y.
Journal of Biotechnology 247
: 42-49.
10 April 2017
Identification of individuals by trait prediction using
whole-genome sequencing data.
Lippert, C., Sabatini, R., Maher, M.C., Kang, E.Y., Lee, S., Arikan, O., Harley, A., Bernal, A., Garst, P., Lavrenko, V., Yocum, K., Wong, T., Zhu, M., Yang, W.Y., Chang, C., Lu, T., Lee, C.W.H., Hicks, B., Ramakrishnan, S., Tang, H., Xie, C., Piper, J., Brewerton, S., Turpaz, Y., Telenti, A., Roby, R.K., Och, F.J. and Venter, J.C.
Proceedings of the National Academy of Sciences of the United States of America 114
(38): 10166-10171.
19 September 2017
Downregulation of Plzf gene ameliorates metabolic and cardiac traits in the spontaneously hypertensive rat.
Liška, F., Landa, V., Zidek, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Strnad, H., Trnovská, J., Škop, V., Kazdová, L., Starker, C.G., Voytas, D.F., Izsvák, Z., Mancini, M., Šeda, O., Křen, V. and Pravenec, M.
Hypertension 69
(6): 1084-1091.
June 2017
Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma.
Lodrini, M., Sprüssel, A., Astrahantseff, K., Tiburtius, D., Konschak, R., Lode, H.N., Fischer, M., Keilholz, U., Eggert, A. and Deubzer, H.E.
Oncotarget 8
(49): 85234-85251.
17 October 2017
Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders.
Lorenz, C., Lesimple, P., Bukowiecki, R., Zink, A., Inak, G., Mlody, B., Singh, M., Semtner, M., Mah, N., Auré, K., Leong, M., Zabiegalov, O., Lyras, E.M., Pfiffer, V., Fauler, B., Eichhorst, J., Wiesner, B., Huebner, N., Priller, J., Mielke, T., Meierhofer, D., Izsvák, Z., Meier, J.C., Bouillaud, F., Adjaye, J., Schuelke, M., Wanker, E.E., Lombès, A. and Prigione, A.
Cell Stem Cell 20
(5): 659-674.e9.
4 May 2017
Unbiased identification of T cell receptors targeting immunodominant peptide-MHC complexes for T cell receptor immunotherapy.
Lorenz, F.K.M., Ellinger, C., Kieback, E., Wilde, S., Lietz, M., Schendel, D.J. and Uckert, W.
Human Gene Therapy 28
(12): 1158-1168.
1 December 2017
Berlin Wild - and the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch.
Luft, F.C.
Journal of Molecular Medicine 95
(6): 567-570.
June 2017
Mesangial renal disease, oxygen sensing, and prolyl hydroxylase.
Luft, F.C.
Journal of Molecular Medicine 95
(3): 235-237.
March 2017
Mesenchymal stem cells provide novel insights into ankylosing spondylitis.
Luft, F.C.
Journal of Molecular Medicine 95
(2): 119-121.
February 2017
What have we learned from the genetics of hypertension?
Luft, F.C.
Medical Clinics of North America 101
(1): 195-206.
January 2017
Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.
Lutter, D., Ullrich, F., Lueck, J.C., Kempa, S. and Jentsch, T.J.
Journal of Cell Science 130
(6): 1122-1133.
15 March 2017
Malnutrition predicts clinical outcome in patients with neuroendocrine neoplasias.
Maasberg, S., Knappe-Drzikova, B., Vonderbeck, D., Jann, H., Weylandt, K.H., Grieser, C., Pascher, A., Schefold, J.C., Pavel, M., Wiedenmann, B., Sturm, A. and Pape, U.F.
Neuroendocrinology 104
(1): 11-25.
2017
A map of human circular RNAs in clinically relevant tissues.
Maass, P.G., Glažar, P., Memczak, S., Dittmar, G., Hollfinger, I., Schreyer, L., Sauer, A.V., Toka, O., Aiuti, A., Luft, F.C. and Rajewsky, N.
Journal of Molecular Medicine 95
(11): 1179-1189.
November 2017
Genome-wide identification of regulatory elements in Sertoli cells.
Maatouk, D.M., Natarajan, A., Shibata, Y., Song, L., Crawford, G.E., Ohler, U. and Capel, B.
Development 144
(4): 720-730.
15 February 2017
Transcriptome-wide identification of RNA-binding protein binding sites using photoactivatable-ribonucleoside-enhanced crosslinking immunoprecipitation (PAR-CLIP).
Maatz, H., Kolinski, M., Hubner, N. and Landthaler, M.
Current Protocols in Molecular Biology 118
: 27.6.1-27.6.19.
3 April 2017
Epigenetics and control of RNAs.
Maatz, H., van Heesch, S., Kreuchwig, F., Faber, A., Adami, E., Hubner, N. and Heinig, M.
Methods in Molecular Biology 1488
: 217-237.
2017
Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II.
Maier, C., Schadock, I., Haber, P.K., Wysocki, J., Ye, M., Kanwar, Y., Flask, C.A., Yu, X., Hoit, B.D., Adams, G.N., Schmaier, A.H., Bader, M. and Batlle, D.
Journal of Molecular Medicine 95
(5): 473-486.
May 2017
DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.
Mamlouk, S., Childs, L.H., Aust, D., Heim, D., Melching, F., Oliveira, C., Wolf, T., Durek, P., Schumacher, D., Blaeker, H., von Winterfeld, M., Gastl, B., Moehr, K., Menne, A., Zeugner, S., Redmer, T., Lenze, D., Tierling, S., Moebs, M., Weichert, W., Folprecht, G., Blanc, E., Beule, D., Schaefer, R., Morkel, M., Klauschen, F., Leser, U. and Sers, C.
Nature Communications 8
: 14093.
25 January 2017
The technical report on sodium intake and cardiovascular disease in low- and middle-income countries by the joint working group of the World Heart Federation, the European Society of Hypertension and the European Public Health Association.
Mancia, G., Oparil, S., Whelton, P.K., McKee, M., Dominiczak, A., Luft, F.C., AlHabib, K., Lanas, F., Damasceno, A., Prabhakaran, D., La Torre, G., Weber, M., O'Donnell, M., Smith, S.C. and Narula, J.
European Heart Journal 38
(10): 712-719.
7 March 2017
Sparse probit linear mixed model.
Mandt, S., Wenzel, F., Nakajima, S., Cunningham, J., Lippert, C. and Kloft, M.
Machine Learning 106
(9-10): 1621-1642.
October 2017
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.
Marenholz, I., Grosche, S., Kalb, B., Rüschendorf, F., Blümchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Röblitz, H., Yürek, S., Tschirner, S., Hong, X., Wang, X., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hübner, N., Niggemann, B., Beyer, K. and Lee, Y.A.
Nature Communications 8
(1): 1056.
20 October 2017
Quantitative proteomic analysis of Parkin substrates in Drosophila neurons.
Martinez, A., Lectez, B., Ramirez, J., Popp, O., Sutherland, J.D., Urbe, S., Dittmar, G., Clague, M.J. and Mayor, U.
Molecular Neurodegeneration 12
(1): 29.
11 April 2017
Genomewide association study of peanut allergy reproduces association with amino acid polymorphisms in HLA-DRB1.
Martino, D.J., Ashley, S., Koplin, J., Ellis, J., Saffery, R., Dharmage, S.C., Gurrin, L., Matheson, M.C., Kalb, B., Marenholz, I., Beyer, K., Lee, Y.A., Hong, X., Wang, X., Vukevic, D., Motyer, A., Leslie, S., Allen, K.J. and Ferreira, M.A.R.
Clinical and Experimental Allergy 47
(2): 217-223.
February 2017
Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
Mathivet, T., Bouleti, C., Van Woensel, M., Stanchi, F., Verschuere, T., Phng, L.K., Dejaegher, J., Balcer, M., Matsumoto, K., Georgieva, P.B., Belmans, J., Sciot, R., Stockmann, C., Mazzone, M., De Vleeschouwer, S. and Gerhardt, H.
EMBO Molecular Medicine 9
(12): 1629-1645.
1 December 2017
Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Mattei, D., Ivanov, A., Ferrai, C., Jordan, P., Guneykaya, D., Buonfiglioli, A., Schaafsma, W., Przanowski, P., Deuther-Conrad, W., Brust, P., Hesse, S., Patt, M., Sabri, O., Ross, T.L., Eggen, B.J.L., Boddeke, E.W.G.M., Kaminska, B., Beule, D., Pombo, A., Kettenmann, H. and Wolf, S.A.
Translational Psychiatry 7
(5): e1120.
9 May 2017
Cell-cell communication mediated by the CAR subgroup of immunoglobulin cell adhesion molecules in health and disease.
Matthäus, C., Langhorst, H., Schütz, L., Jüttner, R. and Rathjen, F.G.
Molecular and Cellular Neuroscience 81
: 32-40.
June 2017
The adenosine generating enzymes CD39/CD73 control microglial processes ramification in the mouse brain.
Matyash, M., Zabiegalov, O., Wendt, S., Matyash, V. and Kettenmann, H.
PLoS ONE 12
(4): e0175012.
4 April 2017
Renal function is independently associated with circulating betatrophin.
Maurer, L., Schwarz, F., Fischer-Rosinsky, A., Schlueter, N., Brachs, S., Moehlig, M., Pfeiffer, A., Mai, K., Spranger, J. and Bobbert, T.
PLoS ONE 12
(3): e0173197.
3 March 2017
Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution.
Mauri, M., Kirchner, M., Aharoni, R., Ciolli Mattioli, C., van den Bruck, D., Gutkovitch, N., Modepalli, V., Selbach, M., Moran, Y. and Chekulaeva, M.
Nucleic Acids Research 45
(2): 938-950.
25 January 2017
Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function.
McDermott-Roe, C., Leleu, M., Rowe, G.C., Palygin, O., Bukowy, J.D., Kuo, J., Rech, M., Hermans-Beijnsberger, S., Schaefer, S., Adami, E., Creemers, E.E., Heinig, M., Schroen, B., Arany, Z., Petretto, E. and Geurts, A.M.
PLoS ONE 12
(2): e0170458.
3 February 2017
Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Melo, A.A., Hegde, B.G., Shah, C., Larsson, E., Isas, J.M., Kunz, S., Lundmark, R., Langen, R. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 114
(22): 5629-5634.
30 May 2017
proGenomes: a resource for consistent functional and taxonomic annotations of prokaryotic genomes.
Mende, D.R., Letunic, I., Huerta-Cepas, J., Li, S.S., Forslund, K., Sunagawa, S. and Bork, P.
Nucleic Acids Research 45
(D1): D529-D534.
4 January 2017
An integrative framework reveals signaling-to-transcription events in toll-like receptor signaling.
Mertins, P., Przybylski, D., Yosef, N., Qiao, J., Clauser, K., Raychowdhury, R., Eisenhaure, T.M., Maritzen, T., Haucke, V., Satoh, T., Akira, S., Carr, S.A., Regev, A., Hacohen, N. and Chevrier, N.
Cell Reports 19
(13): 2853-2866.
27 June 2017
HLA-MA: simple yet powerful matching of samples using HLA typing results.
Messerschmidt, C., Holtgrewe, M. and Beule, D.
Bioinformatics 33
(14): 2241-2242.
15 July 2017
In silico methods for co-transcriptional RNA secondary structure prediction and for investigating alternative RNA structure expression.
Meyer, I.M.
Methods 120
: 3-16.
1 May 2017
Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells.
Middelkamp, S., van Heesch, S., Braat, A.K., de Ligt, J., van Iterson, M., Simonis, M., van Roosmalen, M.J., Kelder, M.J.E., Kruisselbrink, E., Hochstenbach, R., Verbeek, N.E., Ippel, E.F., Adolfs, Y., Pasterkamp, R.J., Kloosterman, W.P., Kuijk, E.W. and Cuppen, E.
Genome Medicine 9
(1): 9.
26 January 2017
Patients with multiple sclerosis demonstrate reduced subbasal corneal nerve fibre density.
Mikolajczak, J., Zimmermann, H., Kheirkhah, A., Kadas, E.M., Oberwahrenbrock, T., Muller, R., Ren, A., Kuchling, J., Dietze, H., Prüss, H., Paul, F., Hamrah, P. and Brandt, A.U.
Multiple Sclerosis Journal 23
(14): 1847-1853.
1 December 2017
Genomic characterization of murine monocytes reveals C/EBPβ transcription factor dependence of Ly6C(-) cells.
Mildner, A., Schönheit, J., Giladi, A., David, E., Lara-Astiaso, D., Lorenzo-Vivas, E., Paul, F., Chappell-Maor, L., Priller, J., Leutz, A., Amit, I. and Jung, S.
Immunity 46
(5): 849-862.
16 May 2017
DDX54 regulates transcriptome dynamics during DNA damage response.
Milek, M., Imami, K., Mukherjee, N., De Bortoli, F., Zinnall, U., Hazapis, O., Trahan, C., Oeffinger, M., Heyd, F., Ohler, U., Selbach, M. and Landthaler, M.
Genome Research 27
(8): 1344-1359.
August 2017
Tumor-infiltrating merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival.
Miller, N.J., Church, C.D., Dong, L., Crispin, D., Fitzgibbon, M.P., Lachance, K., Jing, L., Shinohara, M., Gavvovidis, I., Willimsky, G., McIntosh, M., Blankenstein, T., Koelle, D.M. and Nghiem, P.
Cancer Immunology Research 5
(2): 137-147.
February 2017
Bioinformatics analysis of functional associations of PTMs.
Minguez, P. and Bork, P.
Methods in Molecular Biology 1558
(1558): 303-320.
2 February 2017
An entropic gradient structure for lindblad equations and couplings of quantum systems to macroscopic models.
Mittnenzweig, M. and Mielke, A.
Journal of Statistical Physics 167
(2): 205-233.
April 2017
Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants.
Mlody, B., Wruck, W., Martins, S., Sperling, K. and Adjaye, J.
Scientific Reports 7
(1): 7516.
8 August 2017
Dysregulation of circulating autoantibodies against VEGF-A, VEGFR-1 and PlGF in preeclampsia - a role in placental and vascular health?
Moe, K., Heidecke, H., Dechend, R. and Staff, A.C.
Pregnancy Hypertension 10
: 83-89.
October 2017
One-pot and gram-scale synthesis of biodegradable polyglycerols under ambient conditions: nanocarriers for intradermal drug delivery.
Mohammadifar, E., Zabihi, F., Tu, Z., Hedtrich, S., Nemati Kharat, A., Adeli, M. and Haag, R.
Polymer Chemistry 8
(47): 7375-7383.
21 December 2017
Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy.
Montag, J., Syring, M., Rose, J., Weber, A.L., Ernstberger, P., Mayer, A.K., Becker, E., Keyser, B., Dos Remedios, C., Perrot, A., van der Velden, J., Francino, A., Navarro-Lopez, F., Ho, C.Y., Brenner, B. and Kraft, T.
Journal of Muscle Research and Cell Motility 38
(3-4): 291-302.
August 2017
Novel compound heterozygous mutations in TELO2 in a patient with severe expression of You-Hoover-Fong syndrome.
Moosa, S., Altmüller, J., Lyngbye, T., Christensen, R., Li, Y., Nürnberg, P., Yigit, G., Vogel, I. and Wollnik, B.
Molecular Genetics & Genomic Medicine 5
(5): 580-584.
September 2017
Confirmation of CAGSSS syndrome as a distinct entity in a Danish patient with a novel homozygous mutation in IARS2.
Moosa, S., Haagerup, A., Gregersen, P.A., Petersen, K.K., Altmüller, J., Thiele, H., Nürnberg, P., Cho, T.J., Kim, O.H., Nishimura, G., Wollnik, B. and Vogel, I.
American Journal of Medical Genetics Part A 173
(4): 1102-1108.
April 2017
High aminopeptidase A activity contributes to blood pressure control in ob/ob mice by AT2 receptor-dependent mechanism.
Morais, R.L., Hilzendeger, A.M., Visniauskas, B., Todiras, M., Alenina, N., Mori, M.A., Araújo, R.C., Nakaie, C.R., Chagas, J.R., Carmona, A.., Bader, M. and Pesquero, J.B.
American Journal of Physiology Heart and Circulatory Physiology 312
(3): H437-H445.
1 March 2017
Chaperone-mediated regulation of choline acetyltransferase protein stability and activity by HSC/HSP70, HSP90, and p97/VCP.
Morey, T.M., Winick-Ng, W., Seah, C. and Rylett, R.J.
Frontiers in Molecular Neuroscience 10
: 415.
December 2017
Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.
Morgenstern, Y., Das Adhikari, U., Ayyash, M., Elyada, E., Tóth, B., Moor, A., Itzkovitz, S. and Ben-Neriah, Y.
EMBO Journal 36
(20): 3046-3061.
16 October 2017
Congenital deafness is associated with specific somatosensory deficits in adolescents.
Moshourab, R., Bégay, V., Wetzel, C., Walcher, J., Middleton, S., Gross, M. and Lewin, G.R.
Scientific Reports 7
(1): 4251.
26 June 2017
Rodents and humans are able to detect the odour of L-Lactate.
Mosienko, V., Chang, A.J., Alenina, N., Teschemacher, A.G. and Kasparov, S.
PLoS ONE 12
(5): e0178478.
25 May 2017
Developmental origin and maintenance of distinct testicular macrophage populations.
Mossadegh-Keller, N., Gentek, R., Gimenez, G., Bigot, S., Mailfert, S. and Sieweke, M.H.
Journal of Experimental Medicine 214
(10): 2829-2841.
2 October 2017
Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression.
Mudduluru, G., Ilm, K., Fuchs, S. and Stein, U.
Oncotarget 8
(13): 21081-21094.
28 March 2017
Investigation of naturally occurring single-nucleotide variants in human TAAR1.
Muehlhaus, J., Dinter, J., Jyrch, S., Teumer, A., Jacobi, S.F., Homuth, G., Kuehnen, P., Wiegand, S., Grueters, A., Voelzke, H., Raile, K., Kleinau, G., Krude, H. and Biebermann, H.
Frontiers in Pharmacology 8
: 807.
24 November 2017
Integrative classification of human coding and noncoding genes through RNA metabolism profiles.
Mukherjee, N., Calviello, L., Hirsekorn, A., de Pretis, S., Pelizzola, M. and Ohler, U.
Nature Structural & Molecular Biology 24
(1): 86-96.
January 2017
Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Mönke, G., Cristiano, E., Finzel, A., Friedrich, D., Herzel, H., Falcke, M. and Loewer, A.
Scientific Reports 7
: 46571.
18 April 2017
CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis.
Müller, I., Pappritz, K., Savvatis, K., Puhl, K., Dong, F., El-Shafeey, M., Hamdani, N., Hamann, I., Noutsias, M., Infante-Duarte, C., Linke, W.A., Van Linthout, S. and Tschöpe, C.
PLoS ONE 12
(8): e0182643.
11 August 2017
Epidemiological, genetic, and clinical characterization by age of newly diagnosed acute myeloid leukemia based on an academic population-based registry study (AMLSG BiO).
Nagel, G., Weber, D., Fromm, E., Erhardt, S., Lübbert, M., Fiedler, W., Kindler, T., Krauter, J., Brossart, P., Kündgen, A., Salih, H.R., Westermann, J., Wulf, G., Hertenstein, B., Wattad, M., Götze, K., Kraemer, D., Heinicke, T., Girschikofsky, M., Derigs, H.G., Horst, H.A., Rudolph, C., Heuser, M., Göhring, G., Teleanu, V., Bullinger, L., Thol, F., Gaidzik, V.I., Paschka, P., Döhner, K., Ganser, A., Döhner, H. and Schlenk, R.F.
Annals of Hematology 96
(12): 1993-2003.
1 December 2017
microRNA-184 induces a commitment switch to epidermal differentiation.
Nagosa, S., Leesch, F., Putin, D., Bhattacharya, S., Altshuler, A., Serror, L., Amitai-Lange, A., Nasser, W., Aberdam, E., Rouleau, M., Tattikota, S.G., Poy, M.N., Aberdam, D. and Shalom-Feuerstein, R.
Stem Cell Reports 9
(6): 1991-2004.
12 December 2017
Hypoxia induces heart regeneration in adult mice.
Nakada, Y., Canseco, D.C., Thet, S., Abdisalaam, S., Asaithamby, A., Santos, C.X., Shah, A.M., Zhang, Hua, Faber, J.E., Kinter, M.T., Szweda, L.I., Xing, C., Hu, Z., Deberardinis, R.J., Schiattarella, G., Hill, J.A., Oz, O., Lu, Z., Zhang, C.C., Kimura, W. and Sadek, H.A.
Nature 541
(7636): 222-227.
12 January 2017
Identification of the elementary structural units of the DNA damage response.
Natale, F., Rapp, A., Yu, W., Maiser, A., Harz, H., Scholl, A., Grulich, S., Anton, T., Hoerl, D., Chen, W., Durante, M., Taucher-Scholz, G., Leonhardt, H. and Cardoso, M.C.
Nature Communications 8
: 15760.
12 June 2017
The RAD51C exonic splice-site mutations c.404G>C and c.404G>T are associated with familial breast and ovarian cancer.
Neidhardt, G., Becker, A., Hauke, J., Horváth, J., Bogdanova Markov, N., Heilmann-Heimbach, S., Hellebrand, H., Thiele, H., Altmüller, J., Nürnberg, P., Meindl, A., Rhiem, K., Blümcke, B., Wappenschmidt, B., Schmutzler, R.K. and Hahnen, E.
European Journal of Cancer Prevention 26
(2): 165-169.
March 2017
Association between loss-of-function mutations within the FANCM gene and early-onset familial breast cancer.
Neidhardt, G., Hauke, J., Ramser, J., Groß, E., Gehrig, A., Müller, C.R., Kahlert, A.K., Hackmann, K., Honisch, E., Niederacher, D., Heilmann-Heimbach, S., Franke, A., Lieb, W., Thiele, H., Altmüller, J., Nürnberg, P., Klaschik, K., Ernst, C., Ditsch, N., Jessen, F., Ramirez, A., Wappenschmidt, B., Engel, C., Rhiem, K., Meindl, A., Schmutzler, R.K. and Hahnen, Eric
JAMA Oncology 3
(9): 1245-1248.
1 September 2017
Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.
Nieborowska-Skorska, M., Sullivan, K., Dasgupta, Y., Podszywalow-Bartnicka, P., Hoser, G., Maifrede, S., Martinez, E., Di Marcantonio, D., Bolton-Gillespie, E., Cramer-Morales, K., Lee, J., Li, M., Slupianek, A., Gritsyuk, D., Cerny-Reiterer, S., Seferynska, I., Stoklosa, T., Bullinger, L., Zhao, H., Gorbunova, V., Piwocka, K., Valent, P., Civin, C.I., Muschen, M., Dick, J.E., Wang, J.C., Bhatia, S., Bhatia, R., Eppert, K., Minden, M.D., Sykes, S.M. and Skorski, T.
Journal of Clinical Investigation 127
(6): 2392-2406.
1 June 2017
High field cardiac magnetic resonance imaging: a case for ultrahigh field cardiac magnetic resonance.
Niendorf, T., Schulz-Menger, J., Paul, K., Huelnhagen, T., Ferrari, V.A. and Hodge, R.
Circulation Cardiovascular Imaging 10
(6): e005460.
June 2017
High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph.
Nikpey, E., Karlsen, T.V., Rakova, N., Titze, J.M., Tenstad, O. and Wiig, H.
Hypertension 69
(4): 660-668.
April 2017
Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies.
Nimptsch, K., Song, M., Aleksandrova, K., Katsoulis, M., Freisling, H., Jenab, M., Gunter, M.J., Tsilidis, K.K., Weiderpass, E., Bueno-De-Mesquita, H.B., Chong, D.Q., Jensen, M.K., Wu, C., Overvad, K., Kühn, T., Barrdahl, M., Melander, O., Jirstrom, K., Peeters, P.H., Sieri, S., Panico, S., Cross, A.J., Riboli, E., Van Guelpen, B., Myte, R., Huerta, J.M., Rodriguez-Barranco, M., Quirós, J.R., Dorronsoro, M., Tjønneland, A., Olsen, A., Travis, R., Boutron-Ruault, M.C., Carbonnel, F., Severi, G., Bonet, C., Palli, D., Janke, J., Lee, Y.A., Boeing, H., Giovannucci, E.L., Ogino, S., Fuchs, C.S., Rimm, E., Wu, K., Chan, A.T. and Pischon, T.
European Journal of Epidemiology 32
(5): 419-430.
May 2017
Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features.
Niturad, C.E., Lev, D., Kalscheuer, V.M., Charzewska, A., Schubert, J., Lerman-Sagie, T., Kroes, H.Y., Oegema, R., Traverso, M., Specchio, N., Lassota, M., Chelly, J., Bennett-Back, O., Carmi, N., Koffler-Brill, T., Iacomino, M., Trivisano, M., Capovilla, G., Striano, P., Nawara, M., Rzonca, S., Fischer, U., Bienek, M., Jensen, C., Hu, H., Thiele, H., Altmüller, J., Krause, R., May, P., Becker, F., Balling, R., Biskup, S., Haas, S.A., Nürnberg, P., van Gassen, K.L.I., Lerche, H., Zara, F., Maljevic, S. and Leshinsky-Silver, E.
Brain 140
(11): 2879-2894.
1 November 2017
Participants' decision to enroll in cohort studies with biobanks: quantitative insights from two german studies.
Nobile, H., Borry, P., Pischon, T., Steinbrecher, A., Boeing, H., Vigl, M. and Bergmann, M.M.
Personalized Medicine 14
(6): 477-485.
November 2017
FANTOM5 CAGE profiles of human and mouse samples.
Noguchi, S., Arakawa, T., Fukuda, S., Furuno, M., Hasegawa, A., Hori, F., Ishikawa-Kato, S., Kaida, K., Kaiho, A., Kanamori-Katayama, M., Kawashima, T., Kojima, M., Kubosaki, A., Manabe, R.I., Murata, M., Nagao-Sato, S., Nakazato, K., Ninomiya, N., Nishiyori-Sueki, H., Noma, S., Saijyo, E., Saka, A., Sakai, M., Simon, C., Suzuki, N., Tagami, M., Watanabe, S., Yoshida, S., Arner, P., Axton, R.A., Babina, M., Baillie, J.K., Barnett, T.C., Beckhouse, A.G., Blumenthal, A., Bodega, B., Bonetti, A., Briggs, J., Brombacher, F., Carlisle, A.J., Clevers, H.C., Davis, C.A., Detmar, M., Dohi, T., Edge, A.S.B., Edinger, M., Ehrlund, A., Ekwall, K., Endoh, M., Enomoto, H., Eslami, A., Fagiolini, M., Fairbairn, L., Farach-Carson, M.C., Faulkner, G.J., Ferrai, C., Fisher, M.E., Forrester, L.M., Fujita, R., Furusawa, J.I., Geijtenbeek, T.B., Gingeras, T., Goldowitz, D., Guhl, S., Guler, R., Gustincich, S., Ha, T.J., Hamaguchi, M., Hara, M., Hasegawa, Y., Herlyn, M., Heutink, P., Hitchens, K.J., Hume, D.A., Ikawa, T., Ishizu, Y., Kai, C., Kawamoto, H., Kawamura, Y.I., Kempfle, J.S., Kenna, T.J., Kere, J., Khachigian, L.M., Kitamura, T., Klein, S., Klinken, S.P., Knox, A.J., Kojima, S., Koseki, H., Koyasu, S., Lee, W., Lennartsson, A.s, Mackay-Sim, A., Mejhert, N., Mizuno, Y., Morikawa, H., Morimoto, M., Moro, K., Morris, K.J., Motohashi, H., Mummery, C.L., Nakachi, Y., Nakahara, F., Nakamura, T., Nakamura, Y., Nozaki, T., Ogishima, S., Ohkura, N., Ohno, H., Ohshima, M., Okada-Hatakeyama, M., Okazaki, Y., Orlando, V., Ovchinnikov, D.A., Passier, R., Patrikakis, M., Pombo, A., Pradhan-Bhatt, S., Qin, X.Y., Rehli, M., Rizzu, P., Roy, S., Sajantila, A., Sakaguchi, S., Sato, H., Satoh, H., Savvi, S., Saxena, A., Schmidl, C., Schneider, C., Schulze-Tanzil, G.G., Schwegmann, A., Sheng, G., Shin, J.W., Sugiyama, D., Sugiyama, T., Summers, K.M., Takahashi, N., Takai, J., Tanaka, H., Tatsukawa, H., Tomoiu, A., Toyoda, H., van de Wetering, M., van den Berg, L.M., Verardo, R., Vijayan, D., Wells, C.A., Winteringham, L.N., Wolvetang, E., Yamaguchi, Y., Yamamoto, M., Yanagi-Mizuochi, C., Yoneda, M., Yonekura, Y., Zhang, P.G., Zucchelli, S., Abugessaisa, I., Arner, E., Harshbarger, J., Kondo, A., Lassmann, T., Lizio, M., Sahin, S., Sengstag, T., Severin, J., Shimoji, H., Suzuki, M., Suzuki, H., Kawai, J., Kondo, N., Itoh, M., Daub, C.O., Kasukawa, T., Kawaji, H., Carninci, P., Forrest, A.R.R. and Hayashizaki, Y.
Scientific Data 4
: 170112.
29 August 2017
Radiofrequency applicator concepts for simultaneous MR imaging and hyperthermia treatment of glioblastoma multiforme: a 298 MHz(7.0 Tesla) thermal magnetic resonancesimulation study.
Oberacker, E., Kuehne, A., Nadobny, J., Zschaeck, S., Weihrauch, M., Waiczies, H., Ghadjar, P., Wust, P., Niendorf, T. and Winter, L.
Current Directions in Biomedical Engineering 3
(2): 473-477.
September 2017
Magnetic resonance safety and compatibility of tantalum markers used in proton beam therapy for intraocular tumors: a 7.0 Tesla study.
Oberacker, E., Paul, K., Huelnhagen, T., Oezerdem, C., Winter, L., Pohlmann, A., Boehmert, L., Stachs, O., Heufelder, J., Weber, A., Rehak, M., Seibel, I. and Niendorf, T.
Magnetic Resonance in Medicine 78
(4): 1533-1546.
October 2017
Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation.
Oberheide, K., Puchkov, D. and Jentsch, T.J.
Journal of Biological Chemistry 292
(26): 10845-10854.
30 June 2017
Protein corona formation on colloidal polymeric nanoparticles and polymeric panogels: impact on cellular uptake, toxicity, immunogenicity, and drug release properties.
Obst, K., Yealland, G., Balzus, B., Miceli, E., Dimde, M., Weise, C., Eravci, M., Bodmeier, R., Haag, R., Calderón, M., Charbaji, N. and Hedtrich, S.
Biomacromolecules 18
(6): 1762-1771.
12 June 2017
Microstructural visual system changes in AQP4-antibody-seropositive NMOSD.
Oertel, F.C., Kuchling, J., Zimmermann, H., Chien, C., Schmidt, F., Knier, B., Bellmann-Strobl, J., Korn, T., Scheel, M., Klistorner, A., Ruprecht, K., Paul, F. and Brandt, A.U.
Neurology Neuroimmunology & Neuroinflammation 4
(3): e334.
May 2017
Optische Kohaerenztomographie bei Neuromyelitis optica-Spektrum-Erkrankungen [Optical coherence tomography in neuromyelitis optica spectrum disorders].
Oertel, F.C., Zimmermann, H., Brandt, A.U. and Paul, F.
Nervenarzt 88
(12): 1411-1420.
December 2017
A diet rich in Omega-3 fatty acids enhances expression of soluble epoxide hydrolase in murine brain.
Ostermann, A.I., Reutzel, M., Hartung, N., Franke, N., Kutzner, L., Schoenfeld, K., Weylandt, K.H., Eckert, G.P. and Schebb, N.H.
Prostaglandins & Other Lipid Mediators 133
: 79-87.
November 2017
Modulation of the endogenous omega-3 fatty acid and oxylipin profile in vivo - a comparison of the fat-1 transgenic mouse with C57BL/6 wildtype mice on an omega-3 fatty acid enriched diet.
Ostermann, A.I., Waindok, P., Schmidt, M.J., Chiu, C.Y., Smyl, C., Rohwer, N., Weylandt, K.H. and Schebb, N.H.
PLoS ONE 12
(9): e0184470.
8 September 2017
Protein kinase A regulates C-terminally truncated Ca(V) 1.2 in Xenopus oocytes: roles of N- and C-termini of the α(1C) subunit.
Oz, S., Pankonien, I., Belkacemi, A., Flockerzi, V., Klussmann, E., Haase, H. and Dascal, N.
Journal of Physiology 595
(10): 3181-3202.
15 May 2017
Neuromyelitis optica.
Pache, F., Wildemann, B., Paul, F. and Jarius, S.
Fortschritte der Neurologie Psychiatrie 85
(2): 100-114.
February 2017
Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin.
Paeger, L., Karakasilioti, I., Altmüller, J., Frommolt, P., Brüning, J. and Kloppenburg, P.
eLife 6
: e25770.
20 June 2017
Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy.
Pahle, J., Menzel, L., Niesler, N., Kobelt, D., Aumann, J., Rivera, M. and Walther, W.
BMC Cancer 17
(1): 129.
13 February 2017
The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.
Pajtler, K.W., Sadowski, N., Ackermann, S., Althoff, K., Schönbeck, K., Batzke, K., Schäfers, S., Odersky, A., Heukamp, L., Astrahantseff, K., Künkele, A., Deubzer, H.E., Schramm, A., Sprüssel, A., Thor, T., Lindner, S., Eggert, A., Fischer, M. and Schulte, J.H.
Oncotarget 8
(4): 6730-6741.
24 January 2017
Translation of circRNAs.
Pamudurti, N.R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., Shenzis, S., Samson, M., Dittmar, G., Landthaler, M., Chekulaeva, M., Rajewsky, N. and Kadener, S.
Molecular Cell 66
(1): 9-21.
6 April 2017
Scattering compensation by focus scanning holographic aberration probing (F-SHARP).
Papadopoulos, I.N., Jouhanneau, J.S., Poulet, J.F.A. and Judkewitz, B.
Nature Photonics 11
(2): 116-123.
February 2017
Single-subject independent component analysis-based intensity normalization in non-quantitative multi-modal structural MRI.
Papazoglou, S., Würfel, J., Paul, F., Brandt, A.U. and Scheel, M.
Human Brain Mapping 38
(7): 3615-3622.
July 2017
Does NGAL reduce costs? A cost analysis of urine NGAL (uNGAL) & serum creatinine (sCr) for acute kidney injury (AKI) diagnosis.
Parikh, A., Rizzo, J.A, Canetta, P., Forster, C., Sise, M., Maarouf, O., Singer, E., Elger, A., Elitok, S., Schmidt-Ott, K., Barasch, J. and Nickolas, T.L
PLoS ONE 12
(5): e0178091.
19 May 2017
β1-adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes.
Park, M., Reddy, G.R., Wallukat, G., Xiang, Y.K. and Steinberg, S.F.
Scientific Reports 7
(1): 7890.
11 August 2017
Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.
Park, T.J., Reznick, J., Peterson, B.L., Blass, G., Omerbašić, D., Bennett, N.C., Kuich, P.H.J.L., Zasada, C., Browe, B.M., Hamann, W., Applegate, D.T., Radke, M.H., Kosten, T., Lutermann, H., Gavaghan, V., Eigenbrod, O., Bégay, V., Amoroso, V. G., Govind, V., Minshall, R.D., Smith, E.S.J., Larson, J., Gotthardt, M., Kempa, S. and Lewin, G.R.
Science 356
(6335): 307-311.
21 April 2017
Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitis.
Paterka, M., Voss, J.O., Werr, J., Reuter, E., Franck, S., Leuenberger, T., Herz, J., Radbruch, H., Bopp, T., Siffrin, V. and Zipp, F.
Journal of Autoimmunity 76
: 108-114.
January 2017
Kognitive Stoerungen bei Multipler Sklerose und anderen autoimmunen Erkrankungen des zentralen Nervensystems [Cognitive dysfunction in multiple sclerosis and other autoimmune disorders in central nervous system].
Paul, F.
Journal fuer Neurologie Neurochirurgie und Psychiatrie 18
(1): 4-10.
2017
Quantitative GTPase affinity purification identifies Rho family protein interaction partners.
Paul, F., Zauber, H., von Berg, L., Rocks, O., Daumke, O. and Selbach, M.
Molecular & Cellular Proteomics 16
(1): 73-85.
1 January 2017
Functional connectivity of large-scale brain networks in patients with anti-NMDA receptor encephalitis: an observational study.
Peer, M., Prüss, H., Ben-Dayan, I., Paul, F., Arzy, S. and Finke, C.
Lancet Psychiatry 4
(10): 768-774.
October 2017
Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Pei, W., Feyerabend, T.B., Rössler, J., Wang, X., Postrach, D., Busch, K., Rode, I., Klapproth, K., Dietlein, N., Quedenau, C., Chen, W., Sauer, S., Wolf, S., Höfer, T. and Rodewald, H.Re.
Nature 548
(7668): 456-460.
24 August 2017
The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice.
Pelz, L., Purfürst, B. and Rathjen, F.G.
Journal of Biological Chemistry 292
(52): 21490-21503.
29 December 2017
Tall height and obesity are associated with an increased risk of aggressive prostate cancer: results from the EPIC cohort study.
Perez-Cornago, A., Appleby, P.N., Pischon, T., Tsilidis, K.K., Tjønneland, A., Olsen, A., Overvad, K., Kaaks, R., Kühn, T., Boeing, H., Steffen, A., Trichopoulou, A., Lagiou, P., Kritikou, M., Krogh, V., Palli, D., Sacerdote, C., Tumino, R., Bueno-de-Mesquita, H.B., Agudo, A., Larrañaga, N., Molina-Portillo, E., Barricarte, A., Chirlaque, M.D., Quirós, J.R., Stattin, P., Häggström, C., Wareham, N., Khaw, K.T., Schmidt, J.A., Gunter, M., Freisling, H., Aune, D., Ward, H., Riboli, Elio, Key, T.J. and Travis, R.C.
BMC Medicine 15
: 115.
13 July 2017
Pontine tegmental cap dysplasia in an extremely preterm infant and review of the literature.
Picker-Minh, S., Hartenstein, S., Proquitte, H., Froehler, S., Raile, V., Kraemer, N., Apeshiotis, S., Leipoldt, M., Kalache, K.D., Morris-Rosendahl, D., Boltshauser, E., Chen, W. and Kaindl, A.M.
Journal of Child Neurology 32
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March 2017
JACUSA: site-specific identification of RNA editing events from replicate sequencing data.
Piechotta, M., Wyler, E., Ohler, U., Landthaler, M. and Dieterich, C.
BMC Bioinformatics 18
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3 January 2017
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Pieper, K., Tan, J., Piccoli, L., Foglierini, M., Barbieri, S., Chen, Y., Silacci-Fregni, C., Wolf, T., Jarrossay, D., Anderle, M., Abdi, A., Ndungu, F.M., Doumbo, O.K., Traore, B., Tran, T.M., Jongo, S., Zenklusen, I., Crompton, P.D., Daubenberger, C., Bull, P.C., Sallusto, F. and Lanzavecchia, A.
Nature 548
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31 August 2017
Stratum corneum targeting by dendritic core-multishell-nanocarriers in a mouse model of psoriasis.
Pischon, H., Radbruch, M., Ostrowski, A., Volz, P., Gerecke, C., Unbehauen, M., Hönzke, S., Hedtrich, S., Fluhr, J.W., Haag, R., Kleuser, B., Alexiev, U., Gruber, A.D. and Mundhenk, L.
Nanomedicine: Nanotechnology, Biology and Medicine 13
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January 2017
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M., Glažar, P., Hernandez-Miranda, L.R., Memczak, S., Wolf, S.A., Rybak-Wolf, A., Filipchyk, A., Klironomos, F., Cerda Jara, C.A., Fenske, P., Trimbuch, T., Zywitza, V., Plass, M., Schreyer, L., Ayoub, S., Kocks, C., Kühn, R., Rosenmund, C., Birchmeier, C. and Rajewsky, N.
Science 357
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22 September 2017
Experimental MRI monitoring of renal blood volume fraction variations en route to renal magnetic resonance oximetry.
Pohlmann, A., Cantow, K., Huelnhagen, T., Grosenick, D., dos Santos Periquito, J., Boehmert, L., Gladytz, T., Waiczies, S., Flemming, B., Seeliger, E. and Niendorf, T.
Tomography 3
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December 2017
The chronically inflamed central nervous system provides niches for long-lived plasma cells.
Pollok, K., Mothes, R., Ulbricht, C., Liebheit, A., Gerken, J.D., Uhlmann, S., Paul, F., Niesner, R., Radbruch, H. and Hauser, A.E.
Acta Neuropathologica Communications 5
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25 November 2017
Dense and accurate whole-chromosome haplotyping of individual genomes.
Porubsky, D., Garg, S., Sanders, A.D., Korbel, J.O., Guryev, V., Lansdorp, P.M. and Marschall, T.
Nature Communications 8
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3 November 2017
Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.
Pose-Utrilla, J., García-Guerra, L., Del Puerto, A., Martin, A., Jurado-Arjona, J., De León-Reyes, N.S., Gamir-Morralla, A., Sebastián-Serrano, A., García-Gallo, M., Kremer, L., Fielitz, J., Ireson, C., Pérez-Álvarez, M.J., Ferrer, I., Hernández, F., Ávila, J., Lasa, M., Campanero, M.R. and Iglesias, T.
Nature Communications 8
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22 December 2017
Caloric restriction in older adults - differential effects of weight loss and reduced weight on brain structure and function.
Prehn, K., Jumpertz von Schwartzenberg, R., Mai, K., Zeitz, U., Witte, A.V., Hampel, D., Szela, A.M., Fabian, S., Grittner, U., Spranger, J. and Floeel, A.
Cerebral Cortex 27
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1 March 2017
IFNα-mediated remodeling of endothelial cells in the bone marrow niche.
Prendergast, Á.M., Kuck, A., van Essen, M., Haas, S., Blaszkiewicz, S. and Essers, M.A.G.
Haematologica 102
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March 2017
Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-α in a gestational age-dependent manner.
Prokesch, A., Blaschitz, A., Bauer, T., Moser, G., Hiden, U., Zadora, J., Dechend, R., Herse, F. and Gauster, M.
Histochemistry and Cell Biology 147
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June 2017
Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia.
Qu, Y., Siggens, L., Cordeddu, L., Gaidzik, V.I., Karlsson, K., Bullinger, L., Döhner, K., Ekwall, K., Lehmann, S. and Lennartsson, A.
Blood 129
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16 February 2017
Different inhibitory potencies of oseltamivir carboxylate, zanamivir, and several tannins on bacterial and viral neuraminidases as assessed in a cell-free fluorescence-based enzyme inhibition assay.
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Molecules 22
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17 November 2017
MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.
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Cancer Letters 403
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10 September 2017
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.
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Nature 551
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16 November 2017
MAD2L2 promotes open chromatin in embryonic stem cells and derepresses the Dppa3 locus.
Rahjouei, A., Pirouz, M., Di Virgilio, M., Kamin, D. and Kessel, M.
Stem Cell Reports 8
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11 April 2017
Protein kinase C enhances plasma membrane expression of cardiac L-type calcium channel, Ca(V)1.2.
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Channels 11
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2 November 2017
Synergistic strategy for multicolor two-photon microscopy: application to the analysis of germinal center reactions in vivo.
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Scientific Reports 7
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2 August 2017
Increased salt consumption induces body water conservation and decreases fluid intake.
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Journal of Clinical Investigation 127
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1 May 2017
Mutations in γ-secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa.
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Journal of Clinical Investigation 127
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3 April 2017
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.
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Nature Neuroscience 20
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August 2017
Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.
Ravindran, E., Hu, H., Yuzwa, S.A., Hernandez-Miranda, L.R., Kraemer, N., Ninnemann, O., Musante, L., Boltshauser, E., Schindler, D., Hübner, A., Reinecker, H.-C., Ropers, H.-H., Birchmeier, C., Miller, F.D., Wienker, T.F., Hübner, C. and Kaindl, A.M.
PLoS Genetics 13
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28 April 2017
Viral infection identifies micropeptides differentially regulated in smORF-containing lncRNAs.
Razooky, B.S., Obermayer, B., O'May, J.B. and Tarakhovsky, A.
Genes 8
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21 August 2017
Chromatin immunoprecipitation (ChIP) protocol for low-abundance embryonic samples.
Rehimi, R., Bartusel, M., Solinas, F., Altmüller, J. and Rada-Iglesias, A.
Journal of Visualized Experiments
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29 August 2017
The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown.
Reichhart, N., Crespo-Garcia, S., Haase, N., Golic, M., Skosyrski, S., Rübsam, A., Herrspiegel, C., Kociok, N., Alenina, N., Bader, M., Dechend, R., Strauss, O. and Joussen, A.M.
Diabetologia 60
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January 2017
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.
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Nature Genetics 49
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April 2017
Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner.
Rharass, T., Lantow, M., Gbankoto, A., Weiss, D.G., Panáková, D. and Lucas, S.
Journal of Biomedical Science 24
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16 October 2017
Effects of heart valve prostheses on phase contrast flow measurements in cardiovascular magnetic resonance - a phantom study.
Richau, J., Dieringer, M.A., Traber, J., von Knobelsdorff-Brenkenhoff, F., Greiser, A., Schwenke, C. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 19
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16 January 2017
Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells.
Riemann, M., Andreas, N., Fedoseeva, M., Meier, E., Weih, D., Freytag, H., Schmidt-Ullrich, R., Klein, U., Wang, Z.Q. and Weih, F.
Journal of Autoimmunity 81
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July 2017
Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K., Shi, Y., Jacobi, A., Kräter, M., Kalupa, M., McGearey, A., Mertlitz, S., Cordes, S., Schrezenmeier, J.F., Mengwasser, J., Westphal, S., Perez-Hernandez, D., Schmitt, C., Dittmar, G., Guck, J. and Penack, O.
Blood 129
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6 April 2017
Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation.
Riffelmacher, T., Clarke, A., Richter, F.C., Stranks, A., Pandey, S., Danielli, S., Hublitz, P., Yu, Z., Johnson, E., Schwerd, T., McCullagh, J., Uhlig, H., Jacobsen, S.E.W. and Simon, A.K.
Immunity 47
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19 September 2017
Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments.
Robson, M.I., de Las Heras, J.I., Czapiewski, R., Sivakumar, A., Kerr, A.R.W. and Schirmer, E.C.
Genome Research 27
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July 2017
The redox environment triggers conformational changes and aggregation of hIAPP in type II diabetes.
Rodriguez Camargo, D.C., Tripsianes, K., Buday, K., Franko, A., Göbl, C., Hartlmüller, C., Sarkar, R., Aichler, M., Mettenleiter, G., Schulz, M., Böddrich, A., Erck, C., Martens, H., Walch, A.K., Madl, T., Wanker, E.E., Conrad, M., de Angelis, M.H. and Reif, B.
Scientific Reports 7
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13 March 2017
Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies.
Rohr, U.P., Herrmann, P., Ilm, K., Zhang, H., Lohmann, S., Reiser, A., Muranyi, A., Smith, J., Burock, S., Osterland, M., Leith, K., Singh, S., Brunhoeber, P., Bowermaster, R., Tie, J., Christie, M., Wong, H.L., Waring, P., Shanmugam, K., Gibbs, P. and Stein, U.
Annals of Oncology 28
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1 August 2017
Addendum zum "Curriculum Kardiale Magnetresonanztomographie (CMR)" [Addendum to "Curriculum Cardiac Magnetic Resonance Imaging (CMRI)"].
Rolf, A., Eitel, I., Schulz-Menger, J., von Knobelsdorff, F., Kelle, S., Müllerleile, K., Steen, H., Bernhardt, P., Jensen, C., Gebker, R. and Bruder, O.
Kardiologe 11
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June 2017
Prospective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells.
Rouhi, A., Miller, C., Grasedieck, S., Reinhart, S., Stolze, B., Döhner, H., Kuchenbauer, F., Bullinger, L., Fröhling, S. and Scholl, C.
Oncotarget 8
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31 January 2017
Monocytes promote crescent formation in anti-myeloperoxidase antibody-induced glomerulonephritis.
Rousselle, A., Kettritz, R. and Schreiber, A.
American Journal of Pathology 187
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September 2017
The answer's in the tail: MYC mRNA has a metabolic sensor that supports cancer chemoresistance.
Royla, N. and Kempa, S.
Molecular & Cellular Oncology 4
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5 July 2017
SamuROI, a python-based software tool for visualization and analysis of dynamic time series imaging at multiple spatial scales.
Rueckl, M., Lenzi, S.C., Moreno-Velasquez, L., Parthier, D., Schmitz, D., Ruediger, S. and Johenning, F.W.
Frontiers in Neuroinformatics 11
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29 June 2017
Astrocytes resist hiv-1 fusion but engulf infected macrophage material.
Russell, R.A., Chojnacki, J., Jones, D.M., Johnson, E., Do, T., Eggeling, C., Padilla-Parra, S. and Sattentau, Q.J.
Cell Reports 18
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7 February 2017
How to tame an endogenous retrovirus: HERVH and the evolution of human pluripotency.
Römer, C., Singh, M., Hurst, L.D. and Izsvák, Z.
Current Opinion in Virology 25
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August 2017
RTK: efficient rarefaction analysis of large datasets.
Saary, P., Forslund, K., Bork, P. and Hildebrand, F.
Bioinformatics 33
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15 August 2017
Quantitative proteomic approach identifies Vpr binding protein as novel host factor supporting influenza A virus infections in human cells.
Sadewasser, A., Paki, K., Eichelbaum, K., Bogdanow, B., Saenger, S., Budt, M., Lesch, M., Hinz, K.P., Herrmann, A., Meyer, T.F., Karlas, A., Selbach, M. and Wolff, T.
Molecular & Cellular Proteomics 16
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1 May 2017
Single-cell template strand sequencing by strand-seq enables the characterization of individual homologs.
Sanders, A.D., Falconer, E., Hills, M., Spierings, D.C.J. and Lansdorp, P.M.
Nature Protocols 12
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June 2017
In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Sanderson, S.L. and Simon, A.K.
Aging Cell 16
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December 2017
Meta-analysis of effect of body mass index on outcomes after transcatheter aortic valve implantation.
Sannino, A., Schiattarella, G.G., Toscano, E., Gargiulo, G., Giugliano, G., Galderisi, M., Losi, M.A., Stabile, E., Cirillo, P., Imbriaco, M., Grayburn, P.A., Trimarco, B. and Esposito, G.
American Journal of Cardiology 119
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15 January 2017
Alterations in the α(2)δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies.
Santolini, I., Celli, R., Cannella, M., Imbriglio, T., Guiducci, M., Parisi, P., Schubert, J., Iacomino, M., Zara, F., Lerche, H., Moyanova, S., Ngomba, R.T., van Luijtelaar, G., Battaglia, G., Bruno, V., Striano, P. and Nicoletti, F.
Epilepsia 58
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November 2017
Glucagon decreases IGF-1 bioactivity in humans, independently of insulin, by modulating its binding proteins.
Sarem, Z., Bumke-Vogt, C., Mahmoud, A.M., Assefa, B., Weickert, M.O., Adamidou, A., Baehr, V., Frystyk, J., Moehlig, M., Spranger, J., Lieske, S., Birkenfeld, A.L., Pfeiffer, A.F.H. and Arafat, A.M.
Journal of Clinical Endocrinology and Metabolism 102
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1 September 2017
Structure of the human chromosome interaction network.
Sarnataro, S., Chiariello, A.M., Esposito, A., Prisco, A. and Nicodemi, M.
PLoS ONE 12
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15 November 2017
Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling.
Sassi, Y., Avramopoulos, P., Ramanujam, D., Grüter, L., Werfel, S., Giosele, S., Brunner, A.D., Esfandyari, D., Papadopoulou, A.S, De Strooper, B., Hübner, N., Kumarswamy, R., Thum, T., Yin, X., Mayr, M., Laggerbauer, B. and Engelhardt, S.
Nature Communications 8
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20 November 2017
Transient cardiomyocyte fusion regulates cardiac development in zebrafish.
Sawamiphak, S., Kontarakis, Z., Filosa, A., Reischauer, S. and Stainier, D.Y.R.
Nature Communications 8
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15 November 2017
Hippocampal characteristics and invariant sequence elements distribution of GLRA2 and GLRA3 C-to-U editing.
Schaefermeier, P. and Heinze, S.
Molecular Syndromology 8
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March 2017
IL11 is a crucial determinant of cardiovascular fibrosis.
Schafer, S., Viswanathan, S., Widjaja, A.A., Lim, W.W., Moreno-Moral, A., DeLaughter, D.M., Ng, B., Patone, G., Chow, K., Khin, E., Tan, J., Chothani, S.P., Ye, L., Rackham, O.J., Ko, N.S., Sahib, N.E., Pua, C.J., Zhen, N.T., Xie, C., Wang, M., Maatz, H., Lim, S., Saar, K., Blachut, S., Petretto, E., Schmidt, S., Putoczki, T., Guimarães-Camboa, N., Wakimoto, H., van Heesch, S., Sigmundsson, K., Lim, S.L., Soon, J.L., Chao, V.T., Chua, Y.L., Tan, T.E., Evans, S.M., Loh, Y.J., Jamal, M.H., Ong, K.K., Chua, K.C., Ong, B.H., Chakaramakkil, M.J., Seidman, J.G., Seidman, C.E., Hubner, N., Sin, K.Y. and Cook, S.A.
Nature 552
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7 December 2017
Titin-truncating variants affect heart function in disease cohorts and the general population.
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Nature Genetics 49
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January 2017
Correlation of florbetaben PET imaging and the amyloid peptide Aβ42 in cerebrospinal fluid.
Schipke, C.G., Koglin, N., Bullich, S., Joachim, L.K., Haas, B., Seibyl, J., Barthel, H., Sabri, O. and Peters, O.
Psychiatry Research 265
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30 July 2017
Gadopentetate but not gadobutrol accumulates in the dentate nucleus of multiple sclerosis patients.
Schlemm, L., Chien, C., Bellmann-Strobl, J., Dörr, J., Wuerfel, J., Brandt, A.U., Paul, F. and Scheel, M.
Multiple Sclerosis Journal 23
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June 2017
Chimeric PD-1:28 receptor upgrades low-avidity T cells and restores effector function of tumor-infiltrating lymphocytes for adoptive cell therapy.
Schlenker, R., Olguín-Contreras, L.F., Leisegang, M., Schnappinger, J., Disovic, A., Rühland, S., Nelson, P.J., Leonhardt, H., Harz, H., Wilde, S., Schendel, D.J., Uckert, W., Willimsky, G. and Noessner, E.
Cancer Research 77
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1 July 2017
Antikoagulation bei Patienten mit chronischer Niereninsuffizienz: Empfehlungen der Arbeitsgemeinschaft "Herz-Niere" der Deutschen Gesellschaft für Kardiologie - Herz- und Kreislaufforschung und der Deutschen Gesellschaft für Nephrologie [Anticoagulation in patients with chronic kidney disease : Recommendations from the working group "Heart-Kidney" of the German Cardiac Society and the German Society of Nephrology].
Schlieper, G., Schwenger, V., Remppis, A., Keller, T., Dechend, R., Massberg, S., Baldus, S., Weinreich, T., Hetzel, G., Floege, J., Mahfoud, F. and Fliser, D.
Internist 58
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May 2017
Ly6C(high) monocytes oscillate in the heart during homeostasis and after myocardial infarction.
Schloss, M.J., Hilby, M., Nitz, K., Guillamat Prats, R., Ferraro, B., Leoni, G., Soehnlein, O., Kessler, T., He, W., Luckow, B., Horckmans, M., Weber, C., Duchene, J. and Steffens, S.
Arteriosclerosis Thrombosis and Vascular Biology 37
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September 2017
Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt, F., Gasparoni, N., Gasparoni, G., Gianmoena, K., Cadenas, C., Polansky, J.K., Ebert, P., Nordstroem, K., Barann, M., Sinha, A., Froehler, S., Xiong, J., Dehghani Amirabad, A., Behjati Ardakani, F., Hutter, B., Zipprich, G., Felder, B., Eils, J., Brors, B., Chen, W., Hengstler, J.G., Hamann, A., Lengauer, T., Rosenstiel, P., Walter, J. and Schulz, M.H.
Nucleic Acids Research 45
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9 January 2017
B-mode ultrasound assessment of pupillary function: feasibility, reliability and normal values.
Schmidt, F., Ruprecht, K., Connolly, F., Maas, M.B., Paul, F., Hoffmann, J., Harms, L. and Schreiber, S.J.
PLoS ONE 12
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6 December 2017
Severe structural and functional visual system damage leads to profound loss of Vision-related quality of life in patients with neuromyelitis optica spectrum disorders.
Schmidt, F., Zimmermann, H., Mikolajczak, J., Oertel, F.C., Pache, F., Weinhold, M., Schinzel, J., Bellmann-Strobl, J., Ruprecht, K., Paul, F. and Brandt, A.U.
Multiple Sclerosis and Related Disorders 11
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January 2017
Olfactory dysfunction in patients with primary progressive MS.
Schmidt, F.A., Maas, M.B., Geran, R., Schmidt, C., Kunte, H., Ruprecht, K., Paul, F., Göktas, Ö. and Harms, L.
Neurology Neuroimmunology & Neuroinflammation 4
(4): e369.
July 2017
Effect of different lipid apheresis methods on plasma polyunsaturated fatty acids.
Schmoecker, C., Kassner, U., Ostermann, A.I., Kiesler, S., Steinhagen-Thiessen, E., Schebb, N.H. and Weylandt, K.H.
Atherosclerosis Supplements 30
: 193-199.
November 2017
Neuregulin-1 mutant mice indicate motor and sensory deficits, indeed few references for schizophrenia endophenotype model.
Schneider, S., Götz, K., Birchmeier, C., Schwegler, H. and Roskoden, T.
Behavioural Brain Research 322
(Pt A): 177-185.
30 March 2017
A straightforward approach to N-substituted-2 H-indazol-2-amines through reductive cyclization.
Schoene, J., Bel Abed, H., Christmann, M. and Nazare, M.
Tetrahedron Letters 58
(16): 1633-1635.
19 April 2017
Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry.
Schopper, S., Kahraman, A., Leuenberger, P., Feng, Y., Piazza, I., Müller, O., Boersema, P.J. and Picotti, P.
Nature Protocols 12
(11): 2391-2410.
November 2017
Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis.
Schreiber, A., Rousselle, A., Becker, J.U., von Mässenhausen, A., Linkermann, A. and Kettritz, R.
Proceedings of the National Academy of Sciences of the United States of America 114
(45): E9618-E9625.
7 November 2017
Computational prediction of immune cell cytotoxicity.
Schrey, A.K., Nickel-Seeber, J., Drwal, M.N., Zwicker, P., Schultze, N., Haertel, B. and Preissner, R.
Food and Chemical Toxicology 107
(Part A): 150-166.
September 2017
Myokarditis im Kindes- und Jugendalter.
Schubert, S., Messroghli, D., Klaassen, S. and Berger, F.
Kardiologie up2date 13
(3): 275-293.
2017
Crystal structure of the tricellulin C-terminal coiled-coil domain reveals a unique mode of dimerization.
Schuetz, A., Radusheva, V., Krug, S.M. and Heinemann, U.
Annals of the New York Academy of Sciences 1405
(1): 147-159.
October 2017
Structural basis for aryl hydrocarbon receptor-mediated gene activation.
Schulte, K.W., Green, E., Wilz, A., Platten, M. and Daumke, O.
Structure 25
(7): 1025-1033.
5 July 2017
Activation-dependent TRAF3 exon 8 alternative splicing is controlled by CELF2 and hnRNP C binding to an upstream intronic element.
Schultz, A.S., Preussner, M., Bunse, M., Karni, R. and Heyd, F.
Molecular and Cellular Biology 37
(7): e.00488-16.
April 2017
Data-based modeling of drug penetration relates human skin barrier function to the interplay of diffusivity and free-energy profiles.
Schulz, R., Yamamoto, K., Klossek, A., Flesch, R., Hönzke, S., Rancan, F., Vogt, A., Blume-Peytavi, U., Hedtrich, S., Schäfer-Korting, M., Rühl, E. and Netz, R.R.
Proceedings of the National Academy of Sciences of the United States of America 114
(14): 3631-3636.
4 April 2017
The developmental emergence of differential brainstem serotonergic control of the sensory spinal cord.
Schwaller, F., Kanellopoulos, A.H. and Fitzgerald, M.
Scientific Reports 7
(1): 2215.
22 May 2017
Plasma inflammation markers of the tumor necrosis factor pathway but not C-reactive protein are associated with processed meat and unprocessed red meat consumption in bavarian adults.
Schwedhelm, C., Pischon, T., Rohrmann, S., Himmerich, H., Linseisen, J. and Nimptsch, K.
Journal of Nutrition 147
(1): 78-85.
1 January 2017
Evolutionary action and structural basis of the allosteric switch controlling β(2)AR functional selectivity.
Schönegge, A.M., Gallion, J., Picard, L.P., Wilkins, A.D., Le Gouill, C., Audet, M., Stallaert, W., Lohse, M.J., Kimmel, M., Lichtarge, O. and Bouvier, M.
Nature Communications 8
(1): 2169.
18 December 2017
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Schütte, M., Risch, T., Abdavi-Azar, N., Boehnke, K., Schumacher, D., Keil, M., Yildiriman, R., Jandrasits, C., Borodina, T., Amstislavskiy, V., Worth, C.L., Schweiger, C., Liebs, S., Lange, M., Warnatz, H.J., Butcher, L.M., Barrett, J.E., Sultan, M., Wierling, C., Golob-Schwarzl, N., Lax, S., Uranitsch, S., Becker, M., Welte, Y., Regan, J.L., Silvestrov, M., Kehler, I., Fusi, A., Kessler, T., Herwig, R., Landegren, U., Wienke, D., Nilsson, M., Velasco, J.A., Garin-Chesa, P., Reinhard, C., Beck, S., Schäfer, R., Regenbrecht, C.R.A., Henderson, D., Lange, B., Haybaeck, J., Keilholz, U., Hoffmann, J., Lehrach, H. and Yaspo, M.L.
Nature Communications 8
: 14262.
10 February 2017
Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy.
Sedaghat-Hamedani, F., Haas, J., Zhu, F., Geier, C., Kayvanpour, E., Liss, M., Lai, A., Frese, K., Pribe-Wolferts, R., Amr, A., Li, D.T., Samani, O.S., Carstensen, A., Bordalo, D.M., Müller, M., Fischer, C., Shao, J., Wang, J., Nie, M., Yuan, L., Haßfeld, S., Schwartz, C., Zhou, M., Zhou, Z., Shu, Y., Wang, M., Huang, K., Zeng, Q., Cheng, L., Fehlmann, T., Ehlermann, P., Keller, A., Dieterich, C., Streckfuß-Bömeke, K., Liao, Y., Gotthardt, M., Katus, H.A. and Meder, B.
European Heart Journal 38
(46): 3449-3460.
7 December 2017
Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes.
Servin-Vences, M.R., Moroni, M., Lewin, G.R. and Poole, K.
eLife 6
: e21074.
30 January 2017
The endothelial transcription factor ERG mediates angiopoietin-1-dependent control of notch signalling and vascular stability.
Shah, A.V., Birdsey, G.M., Peghaire, C., Pitulescu, M.E., Dufton, N.P., Yang, Y., Weinberg, I., Osuna Almagro, L., Payne, L., Mason, J.C., Gerhardt, H., Adams, R.H. and Randi, A.M.
Nature Communications 8
: 16002.
11 July 2017
A retained intron in the 3'-UTR of Calm3 mRNA mediates its Staufen2- and activity-dependent localization to neuronal dendrites.
Sharangdhar, T., Sugimoto, Y., Heraud-Farlow, J., Fernández-Moya, S.M., Ehses, J., Ruiz de Los Mozos, I., Ule, J. and Kiebler, M.A.
EMBO Reports 18
(10): 1762-1774.
1 October 2017
Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.
Siede, D., Rapti, K., Gorska, A.A., Katus, H.A., Altmüller, J., Boeckel, J.N., Meder, B., Maack, C., Völkers, M., Müller, O.J., Backs, J. and Dieterich, C.
Journal of Molecular and Cellular Cardiology 109
: 48-56.
August 2017
The effect of omega-3 fatty acids on central nervous system remyelination in fat-1 mice.
Siegert, E., Paul, F., Rothe, M. and Weylandt, K.H.
BMC Neuroscience 18
(1): 19.
24 January 2017
Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.
Sigal, M., Logan, C.Y., Kapalczynska, M., Mollenkopf, H.J., Berger, H., Wiedenmann, B., Nusse, R., Amieva, M.R. and Meyer, T.F.
Nature 548
(7668): 451-455.
24 August 2017
2017 GPOH guidelines for diagnosis and treatment of patients with neuroblastic tumors.
Simon, T., Hero, B., Schulte, J.H., Deubzer, H., Hundsdoerfer, P., von Schweinitz, D., Fuchs, J., Schmidt, M., Prasad, V., Krug, B., Timmermann, B., Leuschner, I., Fischer, M., Langer, T., Astrahantseff, K., Berthold, F., Lode, H. and Eggert, A.
Klinische Padiatrie 229
(3): 147-167.
May 2017
Identification of an RNA polymerase III regulator linked to disease-associated protein aggregation.
Sin, O., de Jong, T., Mata-Cabana, A., Kudron, M., Zaini, M.A., Aprile, F.A., Seinstra, R.I., Stroo, E., Prins, R.W., Martineau, C.N., Wang, H.H., Hogewerf, Wytse, Steinhof, A., Wanker, E.E., Vendruscolo, M., Calkhoven, C.F., Reinke, V., Guryev, V. and Nollen, E.A.A.
Molecular Cell 65
(6): 1096-1108.
16 March 2017
Generation of an immortalized mesenchymal stem cell line producing a secreted biosensor protein for glucose monitoring.
Siska, E.K., Weisman, I., Romano, J., Ivics, Z., Izsvák, Z., Barkai, U., Petrakis, S. and Koliakos, G.
PLoS ONE 12
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26 September 2017
A population-based prospective study of optic neuritis.
Soelberg, K., Jarius, S., Skejoe, H.P.B., Engberg, H., Mehlsen, J.J., Nilsson, A.C., Madsen, J.S., Reindl, M., Wildemann, B., Grauslund, J., Kyvik, K.O., Smith, T.J., Lillevang, S.T., Paul, F., Weinshenker, B.G. and Asgari, N.
Multiple Sclerosis Journal 23
(14): 1893-1901.
1 December 2017
MR-Untersuchungen bei Patienten mit Herzschrittmachern und implantierbaren Kardioverter-Defibrillatoren : Konsensuspapier der Deutschen Gesellschaft fuer Kardiologie (DGK) und der Deutschen Roentgengesellschaft (DRG) [MRI examinations in patients with cardiac pacemakers and implantable cardioverter defibrilators : Consensus paper of the German Cardiac Society (DKG) and the German Roentgen Society (DRG)].
Sommer, T., Bauer, W., Fischbach, K., Kolb, C., Luechinger, R., Wiegand, U., Lotz, J., Eitel, I., Gutberlet, M., Thiele, H., Schild, H.H., Kelm, M., Quick, H., Schulz-Menger, J., Barkhausen, J. and Baensch, D.
Kardiologe 11
(2): 97-113.
March 2017
MR-Untersuchungen bei Patienten mit Herzschrittmachern und implantierbaren Kardioverter-Defibrillatoren : Konsensuspapier der Deutschen Gesellschaft fuer Kardiologie (DGK) und der Deutschen Roentgengesellschaft (DRG) [MR imaging in patients with cardiac pacemakers and implantable cardioverter Defibrillators : Consensus paper of the German Cardiac Society and the German Roentgen Society].
Sommer, T., Bauer, W., Fischbach, K., Kolb, C., Luechinger, R., Wiegand, U., Lotz, J., Eitel, I., Gutberlet, M., Thiele, H., Schild, H.H., Kelm, M., Quick, H.H., Schulz-Menger, J., Barkhausen, J. and Bänsch, D.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 189
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15 February 2017
Mutations in MYO1H cause a recessive form of central hypoventilation with autonomic dysfunction.
Spielmann, M., Hernandez-Miranda, L.R., Ceccherini, I., Weese-Mayer, D.E., Kragesteen, B.K., Harabula, I., Krawitz, P., Birchmeier, C., Leonard, N. and Mundlos, S.
Journal of Medical Genetics 54
(11): 754-761.
November 2017
The splenic marginal zone shapes the phenotype of leukemia B cells and facilitates their niche-specific retention and survival.
Stache, V., Verlaat, L., Gätjen, M., Heinig, K., Westermann, J., Rehm, A. and Höpken, U.E.
OncoImmunology 6
(6): e1323155.
6 June 2017
BMP signaling regulates satellite cell dependent postnatal muscle growth.
Stantzou, A., Schirwis, E., Swist, S., Alonso-Martin, S., Polydorou, I., Zarrouki, F., Mouisel, E., Beley, C., Julien, A., Le Grand, F., Garcia, L., Colnot, C., Birchmeier, C., Braun, T., Schuelke, M., Relaix, F. and Amthor, H.
Development 144
(15): 2737-2747.
1 August 2017
Pregnancy-associated plasma protein-A2 and anthropometry, lifestyle, and biochemical factors in a human adult population.
Steinbrecher, A., Janke, J., Poy, M.N., Oxvig, C. and Pischon, T.
Scientific Reports 7
(1): 10455.
5 September 2017
Intestinal helminth infection induces highly functional resident memory CD4(+) T cells in mice.
Steinfelder, S., Rausch, S., Michael, D., Kühl, A.A. and Hartmann, S.
European Journal of Immunology 47
(2): 353-363.
February 2017
Pattern of gray matter volumes related to retinal thickness and its association with cognitive function in relapsing-remitting MS.
Stellmann, J.P., Cetin, H., Young, K.L., Hodecker, S., Poettgen, J., Bittersohl, D., Hassenstein, A., Oberwahrenbrock, T., Heesen, C. and Siemonsen, S.
Brain and Behavior 7
(2): e00614.
February 2017
Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response.
Stellmann, J.P., Krumbholz, M., Friede, T., Gahlen, A., Borisow, N., Fischer, K., Hellwig, K., Pache, F., Ruprecht, K., Havla, J., Kümpfel, T., Aktas, O., Hartung, H.P., Ringelstein, M., Geis, C., Kleinschnitz, C., Berthele, A., Hemmer, B., Angstwurm, K., Young, K.L., Schuster, S., Stangel, M., Lauda, F., Tumani, H., Mayer, C., Zeltner, L., Ziemann, U., Linker, R.A., Schwab, M., Marziniak, M., Then Bergh, F., Hofstadt-van Oy, U., Neuhaus, O., Zettl, U., Faiss, J., Wildemann, B., Paul, F., Jarius, S., Trebst, C. and Kleiter, I.
Journal of Neurology Neurosurgery and Psychiatry 88
(8): 639-647.
August 2017
NF-κB activation protects oligodendrocytes against inflammation.
Stone, S., Jamison, S., Yue, Y., Durose, W., Schmidt-Ullrich, R. and Lin, W.
Journal of Neuroscience 37
(38): 9332-9344.
20 September 2017
Mapping the dynamics of the glucocorticoid receptor within the nuclear landscape.
Stortz, M., Presman, D.M., Bruno, L., Annibale, P., Dansey, M.V., Burton, G., Gratton, E., Pecci, A. and Levi, V.
Scientific Reports 7
(1): 6219.
24 July 2017
Eosinophils are required to suppress Th2 responses in Peyer's patches during intestinal infection by nematodes.
Strandmark, J., Steinfelder, S., Berek, C., Kühl, A.A., Rausch, S. and Hartmann, S.
Mucosal Immunology 10
(3): 661-672.
May 2017
Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Streckfuss-Boemeke, K., Tiburcy, M., Fomin, A., Luo, X., Li, W., Fischer, C., Oezcelik, C., Perrot, A., Sossalla, S., Haas, J., Vidal, R.O., Rebs, S., Khadjeh, S., Meder, B., Bonn, S., Linke, W.A., Zimmermann, W.H., Hasenfuss, G. and Guan, K.
Journal of Molecular and Cellular Cardiology 113
: 9-21.
December 2017
Multifrequency magnetic resonance elastography of the brain reveals tissue degeneration in neuromyelitis optica spectrum disorder.
Streitberger, K.J., Fehlner, A., Pache, F., Lacheta, A., Papazoglou, S., Bellmann-Strobl, J., Ruprecht, K., Brandt, A., Braun, J., Sack, I., Paul, F. and Wuerfel, J.
European Radiology 27
(5): 2206-2215.
May 2017
Development of a perfusion platform for dynamic cultivation of in vitro skin models.
Strüver, K., Friess, W. and Hedtrich, S.
Skin pharmacology and physiology 30
(4): 180-189.
August 2017
Therapy for recurrent high-grade gliomas: results of a prospective multicenter study on health-related quality of life.
Stöckelmaier, L., Renovanz, M., König, J., Nickel, K., Hickmann, A.K., Mayer-Steinacker, R., Nadji-Ohl, M., Ganslandt, O., Bullinger, L., Wirtz, C.R. and Coburger, J.
World Neurosurgery 102
: 383-399.
June 2017
Using hiCLIP to identify RNA duplexes that interact with a specific RNA-binding protein.
Sugimoto, Y., Chakrabarti, A.M., Luscombe, N.M. and Ule, J.
Nature Protocols 12
(3): 611-637.
March 2017
Soluble (pro)renin receptor in preeclampsia and diabetic pregnancies.
Sugulle, M., Heidecke, H., Maschke, U., Herse, F., Danser, A.H.J., Mueller, D.N., Staff, A.C. and Dechend, R.
Journal of the American Society of Hypertension 11
(10): 644-652.
October 2017
CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly.
Sukumaran, S.K., Stumpf, M., Salamon, S., Ahmad, I., Bhattacharya, K., Fischer, S., Müller, R., Altmüller, J., Budde, B., Thiele, H., Tariq, M., Malik, N.A., Nürnberg, P., Baig, S.M., Hussain, M.S. and Noegel, A.A.
Molecular Genetics and Genomics 292
(2): 365-383.
April 2017
Direct experimental evidence for halogen-aryl π interactions in solution from molecular torsion balances.
Sun, H., Horatscheck, A., Martos, V., Bartetzko, M., Uhrig, U., Lentz, D., Schmieder, P. and Nazaré, M.
Angewandte Chemie International Edition 56
(23): 6454-6458.
1 June 2017
Molecular simulations suggest a force-dependent mechanism of vinculin activation.
Sun, L., Noel, J.K., Levine, H. and Onuchic, J.N.
Biophysical Journal 113
(8): 1697-1710.
17 October 2017
Single-molecule imaging reveals receptor-G protein interactions at cell surface hot spots.
Sungkaworn, T., Jobin, M.L., Burnecki, K., Weron, A., Lohse, M.J. and Calebiro, D.
Nature 550
(7677): 543-547.
26 October 2017
Reduced mass and diversity of the colonic microbiome in patients with multiple sclerosis and their improvement with ketogenic diet.
Swidsinski, A., Doerffel, Y., Loening-Baucke, V., Gille, C., Goektas, O., Reißhauer, A., Neuhaus, J., Weylandt, K.H., Guschin, A. and Bock, M.
Frontiers in Microbiology 8
: 1141.
28 June 2017
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible.
Szklarczyk, D., Morris, J.H., Cook, H., Kuhn, M., Wyder, S., Simonovic, M., Santos, A., Doncheva, N.T., Roth, A., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 45
(D1): D362-D368.
4 January 2017
Profiling of short-tandem-repeat disease alleles in 12,632 human whole genomes.
Tang, H., Kirkness, E.F., Lippert, C., Biggs, W.H., Fabani, M., Guzman, E., Ramakrishnan, S., Lavrenko, V., Kakaradov, B., Hou, C., Hicks, B., Heckerman, D., Och, F.J., Caskey, C.T., Venter, J.C. and Telenti, A.
American Journal of Human Genetics 101
(5): 700-715.
2 November 2017
A new fate mapping system reveals context-dependent random or clonal expansion of microglia.
Tay, T.L., Mai, D., Dautzenberg, J., Fernández-Klett, F., Lin, G., Sagar, D.M., Datta, M., Drougard, A., Stempfl, T., Ardura-Fabregat, A., Staszewski, O., Margineanu, A., Sporbert, A., Steinmetz, L.M., Pospisilik, J.A., Jung, S., Priller, J., Grün, D., Ronneberger, O. and Prinz, M.
Nature Neuroscience 20
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June 2017
Rapid adaptation to microgravity in mammalian macrophage cells.
Thiel, C.S., de Zélicourt, D., Tauber, S., Adrian, A., Franz, M., Simmet, D.M., Schoppmann, K., Hauschild, S., Krammer, S., Christen, M., Bradacs, G., Paulsen, K., Wolf, S.A., Braun, M., Hatton, J., Kurtcuoglu, V., Franke, S., Tanner, S., Cristoforetti, S., Sick, B., Hock, B. and Ullrich, O.
Scientific Reports 7
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27 February 2017
Heterodimerization of AML1/ETO with CBFβ is required for leukemogenesis but not for myeloproliferation.
Thiel, V.N., Giaimo, B.D., Schwarz, P., Soller, K., Vas, V., Bartkuhn, M., Blätte, T.J., Döhner, K., Bullinger, L., Borggrefe, T., Geiger, H. and Oswald, F.
Leukemia 31
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November 2017
Acute myeloid leukemia derived from lympho-myeloid clonal hematopoiesis.
Thol, F., Klesse, S., Köhler, L., Gabdoulline, R., Kloos, A., Liebich, A., Wichmann, M., Chaturvedi, A., Fabisch, J., Gaidzik, V.I., Paschka, P., Bullinger, L., Bug, G., Serve, H., Göhring, G., Schlegelberger, B., Lübbert, M., Kirchner, H., Wattad, M., Kraemer, D., Hertenstein, B., Heil, G., Fiedler, W., Krauter, J., Schlenk, R.F., Döhner, K., Döhner, H., Ganser, A. and Heuser, M.
Leukemia 31
(6): 1286-1295.
June 2017
Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival.
Thole, T.M., Lodrini, M., Fabian, J., Wuenschel, J., Pfeil, S., Hielscher, T., Kopp-Schneider, A., Heinicke, U., Fulda, S., Witt, O., Eggert, A., Fischer, M. and Deubzer, H.E.
Cell Death & Disease 8
(3): e2635.
2 March 2017
Engineering of PEDF-expressing primary pigment epithelial cells by the SB transposon system delivered by pFAR4 plasmids.
Thumann, G., Harmening, N., Prat-Souteyrand, C., Marie, C., Pastor, M., Sebe, A., Miskey, C., Hurst, L., Diarra, S., Kropp, M., Walter, P., Scherman, D., Ivics, Z., Izsvák, Z. and Johnen, S.
Molecular Therapy - Nucleic Acids 6
: 302-314.
17 March 2017
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Tobe, B.T.D., Crain, A.M., Winquist, A.M., Calabrese, B., Makihara, H., Zhao, W.N., Lalonde, J., Nakamura, H., Konopaske, G., Sidor, M., Pernia, C.D., Yamashita, N., Wada, M., Inoue, Y., Nakamura, F., Sheridan, S.D., Logan, R.W., Brandel, M., Wu, D., Hunsberger, J., Dorsett, L., Duerr, C., Basa, R.C.B., McCarthy, M.J., Udeshi, N.D., Mertins, P., Carr, S.A., Rouleau, G.A., Mastrangelo, L., Li, J., Gutierrez, G.J., Brill, L.M., Venizelos, N., Chen, G., Nye, J.S., Manji, H., Price, J.H., McClung, C.A., Akiskal, H.S., Alda, M., Chuang, D.M.M., Coyle, J.T., Liu, Y., Teng, Y.D., Ohshima, T., Mikoshiba, K., Sidman, R.L., Halpain, S., Haggarty, S.J., Goshima, Y. and Snyder, E.Y.
Proceedings of the National Academy of Sciences of the United States of America 114
(22): E4462-E4471.
30 May 2017
Evaluation of endothelial dysfunction in vivo.
Todiras, M., Alenina, N. and Bader, M.
Methods in Molecular Biology 1527
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2017
Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.
Tripathi, B.K., Grant, T., Qian, X., Zhou, M., Mertins, P., Wang, D., Papageorge, A.G., Tarasov, S.G., Hunter, K.W., Carr, S.A. and Lowy, D.R.
Journal of Cell Biology 216
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4 December 2017
Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.
Tsai, T., Veitinger, S., Peek, I., Busse, D., Eckardt, J., Vladimirova, D., Jovancevic, N., Wojcik, S., Gisselmann, G., Altmüller, J., Ständer, S., Luger, T., Paus, R., Cheret, J. and Hatt, H.
Experimental Dermatology 26
(1): 58-65.
January 2017
Do KV 7.1 channels contribute to control of arterial vascular tone?
Tsvetkov, D., Kaßmann, M., Tano, J.Y., Chen, L., Schleifenbaum, J., Voelkl, J., Lang, F., Huang, Y. and Gollasch, M.
British Journal of Pharmacology 174
(2): 150-162.
January 2017
An immediate-late gene expression module decodes ERK signal duration.
Uhlitz, F., Sieber, A., Wyler, E., Fritsche-Guenther, R., Meisig, J., Landthaler, M., Klinger, B. and Blüthgen, N.
Molecular Systems Biology 13
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3 May 2017
Association of a synonymous SCN1B variant affecting splicing efficiency with Benign Familial Infantile Epilepsy (BFIE).
Usluer, S., Kayserili, M.A., Eken, A.G., Yiş, U., Leu, C., Altmüller, J., Thiele, H., Nürnberg, P., Sander, T. and Çağlayan, S.H.
European Journal of Paediatric Neurology 21
(5): 773-782.
September 2017
RCAS: an RNA centric annotation system for transcriptome-wide regions of interest.
Uyar, B., Yusuf, D., Wurmus, R., Rajewsky, N., Ohler, U. and Akalin, A.
Nucleic Acids Research 45
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2 June 2017
Cancer stem cells regulate cancer-associated fibroblasts via activation of Hedgehog signaling in mammary gland tumors.
Valenti, G., Quinn, H.M., Heynen, G.J.J.E., Lan, L., Holland, J.D., Vogel, R., Wulf-Goldenberg, A. and Birchmeier, W.
Cancer Research 77
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15 April 2017
Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy.
Van Woensel, M., Mathivet, T., Wauthoz, N., Rosière, R., Garg, A.D., Agostinis, P., Mathieu, V., Kiss, R., Lefranc, F., Boon, L., Belmans, J., Van Gool, S.W., Gerhardt, H., Amighi, K. and De Vleeschouwer, S.
Scientific Reports 7
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27 April 2017
The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.
Varano, G., Raffel, S., Sormani, M., Zanardi, F., Lonardi, S., Zasada, C., Perucho, L., Petrocelli, V., Haake, A., Lee, A.K., Bugatti, M., Paul, U., Van Anken, E., Pasqualucci, L., Rabadan, R., Siebert, R., Kempa, S., Ponzoni, M., Facchetti, F., Rajewsky, K. and Casola, S.
Nature 546
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8 June 2017
A multi-step transcriptional and chromatin state cascade underlies motor neuron programming from embryonic stem cells.
Velasco, S., Ibrahim, M.M., Kakumanu, A., Garipler, G., Aydin, B., Al-Sayegh, M.A., Hirsekorn, A., Abdul-Rahman, F., Satija, R., Ohler, U., Mahony, S. and Mazzoni, E.O.
Cell Stem Cell 20
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2 February 2017
Human haematopoietic stem cell lineage commitment is a continuous process.
Velten, L., Haas, S.F., Raffel, S., Blaszkiewicz, S., Islam, S., Hennig, B.P., Hirche, C., Lutz, C., Buss, E.C., Nowak, D., Boch, T., Hofmann, W.K., Ho, A.D., Huber, W., Trumpp, A., Essers, M.A.G. and Steinmetz, L.M.
Nature Cell Biology 19
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April 2017
Differential immunomodulation in human monocytes versus macrophages by filarial cystatin.
Venugopal, G., Mueller, M., Hartmann, S. and Steinfelder, S.
PLoS ONE 12
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15 November 2017
The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex.
Verduci, L., Ferraiuolo, M., Sacconi, A., Ganci, F., Vitale, J., Colombo, T., Paci, P., Strano, S., Macino, G., Rajewsky, N. and Blandino, G.
Genome Biology 18
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20 December 2017
Long-term prevention of congenital thrombotic thrombocytopenic purpura in ADAMTS13 knockout mice by sleeping beauty transposon-mediated gene therapy.
Verhenne, S., Vandeputte, N., Pareyn, I., Izsvák, Z., Rottensteiner, H., Deckmyn, H., De Meyer, S.F. and Vanhoorelbeke, K.
Arteriosclerosis Thrombosis and Vascular Biology 37
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May 2017
A dominant mutation in nuclear receptor interacting protein 1 causes urinary tract malformations via dysregulation of retinoic acid signaling.
Vivante, A., Mann, N., Yonath, H., Weiss, A.C., Getwan, M., Kaminski, M.M., Bohnenpoll, T., Teyssier, C., Chen, J., Shril, S., van der Ven, A.T., Ityel, H., Schmidt, J.M., Widmeier, E., Bauer, S.B., Sanna-Cherchi, S., Gharavi, A.G., Lu, W., Magen, D., Shukrun, R., Lifton, R.P., Tasic, V., Stanescu, H.C., Cavaillès, V., Kleta, R., Anikster, Y., Dekel, B., Kispert, A., Lienkamp, S.S. and Hildebrandt, F.
Journal of the American Society of Nephrology 28
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August 2017
Inhibition of huntingtin exon-1 aggregation by the molecular tweezer CLR01.
Vöpel, T., Bravo-Rodriguez, K., Mittal, S., Vachharajani, S., Gnutt, D., Sharma, A., Steinhof, A., Fatoba, O., Ellrichmann, G., Nshanian, M., Heid, C., Loo, J.A., Klärner, F.-G., Schrader, T., Bitan, G., Wanker, E.E., Ebbinghaus, S. and Sanchez-Garcia, E.
Journal of the American Chemical Society 139
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26 April 2017
Enhanced fluorine-19 MRI sensitivity using a cryogenic radiofrequency probe: technical developments and ex vivo demonstration in a mouse model of neuroinflammation.
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Scientific Reports 7
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29 August 2017
Labeling of cell therapies: How can we get it right?
Waiczies, S., Niendorf, T. and Lombardi, G.
OncoImmunology 6
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20 July 2017
Engineering an achromatic Bessel beam using a phase-only spatial light modulator and an iterative Fourier transformation algorithm.
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Optics Communications 383
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15 January 2017
TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents.
Wallmeyer, L., Dietert, K., Sochorová, M., Gruber, A.D., Kleuser, B., Vávrová, K. and Hedtrich, S.
Scientific Reports 7
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4 April 2017
In vitro and in vivo investigations into the carbene gold chloride and thioglucoside anticancer drug candidates NHC-AuCl and NHC-AuSR.
Walther, W., Dada, O., O’Beirne, C., Ott, I., Sanchez-Sanz, G., Schmidt, C., Werner, C., Zhu, X. and Tacke, M.
Letters in Drug Design & Discovery 14
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2017
Effects of feeding time on daily rhythms of neuropeptide and clock gene expression in the rat hypothalamus.
Wang, D., Opperhuizen, A.L., Reznick, J., Turner, N., Su, Y., Cooney, G.J. and Kalsbeek, A.
Brain Research 1671
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15 September 2017
Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Wang, J., Brackmann, M., Castaño-Díez, D., Kudryashev, M., Goldie, K.N., Maier, T., Stahlberg, H. and Basler, M.
Nature Microbiology 2
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November 2017
Proteome profiling outperforms transcriptome profiling for coexpression based gene function prediction.
Wang, J., Ma, Z., Carr, S.A., Mertins, P., Zhang, H., Zhang, Z., Chan, D.W., Ellis, M.J.C., Townsend, R.R., Smith, R.D., McDermott, J.E., Chen, X., Paulovich, A.G., Boja, E.S., Mesri, M., Kinsinger, C.R., Rodriguez, H., Rodland, K.D., Liebler, D.C. and Zhang, B.
Molecular & Cellular Proteomics 16
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1 January 2017
Decitabine inhibits T cell proliferation via a novel TET2-dependent mechanism and exerts potent protective effect in mouse auto- and allo-immunity models.
Wang, X., Wang, J., Yu, Y., Ma, T., Chen, P., Zhou, B. and Tao, R.
Oncotarget 8
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22 August 2017
Regulated complex assembly safeguards the fidelity of Sleeping Beauty transposition.
Wang, Y., Pryputniewicz-Dobrinska, D., Nagy, E.E., Kaufman, C.D., Singh, M., Yant, S., Wang, J., Dalda, A., Kay, M.A., Ivics, Z. and Izsvák, Z.
Nucleic Acids Research 45
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9 January 2017
EBI2 is highly expressed in multiple sclerosis lesions and promotes early CNS migration of encephalitogenic CD4 T cells.
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Cell Reports 18
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31 January 2017
Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis.
Weber, L., Al-Refae, K., Ebbert, J., Jägers, P., Altmüller, J., Becker, C., Hahn, S., Gisselmann, G. and Hatt, H.
PLoS ONE 12
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8 March 2017
Cell-accurate optical mapping across the entire developing heart.
Weber, M., Scherf, N., Meyer, A.M., Panáková, D., Kohl, P. and Huisken, J.
eLife 6
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29 December 2017
Gene editing in mouse zygotes using the CRISPR/Cas9 system.
Wefers, B., Bashir, S., Rossius, J. and Kühn, R.
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15 May 2017
A new CUL4B variant associated with a mild phenotype and an exceptional pattern of leukoencephalopathy.
Weissbach, S., Reinert, M.C., Altmüller, J., Krätzner, R., Thiele, H., Rosenbaum, T., Nürnberg, P. and Gärtner, J.
American Journal of Medical Genetics Part A 173
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October 2017
Changes in phagocytosis and potassium channel activity in microglia of 5xFAD mice indicate alterations in purinergic signaling in a mouse model of Alzheimer's disease.
Wendt, S., Maricos, M., Vana, N., Meyer, N., Guneykaya, D., Semtner, M. and Kettenmann, H.
Neurobiology of Aging 58
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October 2017
Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts.
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eLife 6
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3 June 2017
Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.
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Nature Neuroscience 20
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February 2017
The effect of low-dose proteasome inhibition on pre-existing atherosclerosis in LDL receptor-deficient mice.
Wilck, N., Fechner, M., Dan, C., Stangl, V., Stangl, K. and Ludwig, A.
International Journal of Molecular Sciences 18
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7 April 2017
Salt-responsive gut commensal modulates T(H)17 axis and disease.
Wilck, N., Matus, M.G., Kearney, S.M., Olesen, S.W., Forslund, K., Bartolomaeus, H., Haase, S., Mähler, A., Balogh, A., Markó, L., Vvedenskaya, O., Kleiner, F.H., Tsvetkov, D., Klug, L., Costea, P.I., Sunagawa, S., Maier, L., Rakova, N., Schatz, V., Neubert, P., Frätzer, C., Krannich, A., Gollasch, M., Grohme, D.A., Côrte-Real, B.F., Gerlach, R.G., Basic, M., Typas, A., Wu, C., Titze, J.M., Jantsch, J., Boschmann, M., Dechend, R., Kleinewietfeld, M., Kempa, S., Bork, P., Linker, R.A., Alm, E.J. and Müller, D.N.
Nature 551
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30 November 2017
Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans.
Wilhelm, T., Byrne, J., Medina, R., Kolundžić, E., Geisinger, J., Hajduskova, M., Tursun, B. and Richly, H.
Genes & Development 31
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1 August 2017
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog).
Will, A.J., Cova, G., Osterwalder, M., Chan, W.L., Wittler, L., Brieske, N., Heinrich, V., de Villartay, J.P., Vingron, M., Klopocki, E., Visel, A., Lupiáñez, D.G. and Mundlos, S.
Nature Genetics 49
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October 2017
Investigation of hippocampal synaptic transmission and plasticity in mice deficient in the actin-binding protein Drebrin.
Willmes, C.G., Mack, T.G.A., Ledderose, J., Schmitz, D., Wozny, C. and Eickholt, B.J.
Scientific Reports 7
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15 February 2017
CDK10 mutations in humans and mice cause severe growth retardation, spine malformations, and developmental delays.
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American Journal of Human Genetics 101
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7 September 2017
Excitatory microcircuits within superficial layers of the medial entorhinal cortex.
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Cell Reports 19
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9 May 2017
Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use.
Wisskirchen, K., Metzger, K., Schreiber, S., Asen, T., Weigand, L., Dargel, C., Witter, K., Kieback, E., Sprinzl, M.F., Uckert, W., Schiemann, M., Busch, D.H., Krackhardt, A.M. and Protzer, U.
PLoS ONE 12
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8 August 2017
GPCR-SSFE 2.0: a fragment-based molecular modeling web tool for Class A G-protein coupled receptors.
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Nucleic Acids Research 45
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3 July 2017
Strategies for analyzing bisulfite sequencing data.
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Journal of Biotechnology 261
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10 November 2017
Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma.
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Leukemia 31
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March 2017
Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection.
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Genome Biology 18
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31 October 2017
Rattus norvegicus BN/SHR liver and heart left ventricle ribosomal RNA depleted directional RNA sequencing.
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BMC Research Notes 10
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11 August 2017
Myeloid-derived suppressor cells promote B-cell production of IgA in a TNFR2-dependent manner.
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Cellular and Molecular Immunology 14
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July 2017
Unique transcriptional programs identify subtypes of AKI.
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Journal of the American Society of Nephrology 28
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June 2017
CuBe: parametric modeling of 3D foveal shape using cubic Bézier.
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Biomedical Optics Express 8
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1 September 2017
The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia.
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November 2017
Influence of the skin barrier on the penetration of topically-applied dexamethasone probed by soft X-ray spectromicroscopy.
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European Journal of Pharmaceutics and Biopharmaceutics 118
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September 2017
Differential impact of glucose administered intravenously and orally on circulating mir-375 levels in human subjects.
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Journal of Clinical Endocrinology and Metabolism 102
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1 October 2017
Perspective: Essential study quality descriptors for data from nutritional epidemiologic research.
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Advances in Nutrition 8
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September 2017
Anisotropic fluctuations in the ribosome determine tRNA kinetics.
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Journal of Physical Chemistry B 121
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30 November 2017
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.
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July 2017
FGF-dependent metabolic control of vascular development.
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Nature 545
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11 May 2017
Antidepressant responsiveness in adulthood is permanently impaired after neonatal destruction of the neurogenic pool.
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Translational Psychiatry 7
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3 January 2017
Influence of dietary insulin scores on survival in colorectal cancer patients.
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British Journal of Cancer 117
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26 September 2017
Gene editing and clonal isolation of human induced pluripotent stem cells using CRISPR/Cas9.
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15 May 2017
Disturbed placental imprinting in preeclampsia leads to altered expression of DLX5, a human-specific early trophoblast marker.
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Circulation 136
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7 November 2017
Analysis of NPM1 splice variants reveals differential expression patterns of prognostic value in acute myeloid leukemia.
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Oncotarget 8
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10 November 2017
2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines.
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European Journal of Heart Failure 19
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January 2017
RNA localization is a key determinant of neurite-enriched proteome.
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Nature Communications 8
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19 September 2017
CDK5RAP2 is required to maintain the germ cell pool during embryonic development.
Zaqout, S., Bessa, P., Krämer, N., Stoltenburg-Didinger, G. and Kaindl, A.M.
Stem Cell Reports 8
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14 February 2017
Pseudotemporal ordering of single cells reveals metabolic control of postnatal ß cell proliferation.
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Cell Metabolism 25
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2 May 2017
DNA base flipping analytical pipeline.
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Biology Methods & Protocols 2
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11 August 2017
RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints.
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Bioinformatics 33
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1 January 2017
Transposition of the bamboo Mariner-like element Ppmar1 in yeast.
Zhou, M.B., Hu, H., Miskey, C., Lazarow, K., Ivics, Z., Kunze, R., Yang, G., Izsvák, Z. and Tang, D.Q.
Molecular Phylogenetics and Evolution 109
: 367-374.
April 2017
Secreted frizzled-related protein 2 and inflammation-induced skeletal muscle atrophy.
Zhu, X., Kny, M., Schmidt, F., Hahn, A., Wollersheim, T., Kleber, C., Weber-Carstens, S. and Fielitz, J.
Critical Care Medicine 45
(2): e169-e183.
February 2017
Safety and in vivo immune assessment of escalating doses of oral laquinimod in patients with RRMS.
Ziemssen, T., Tumani, H., Sehr, T., Thomas, K., Paul, F., Richter, N., Samara, E., Spiegelstein, O., Sorani, E., Bar-Ilan, O., Mimrod, D. and Hayardeny, L.
Journal of Neuroinflammation 14
(1): 172.
31 August 2017
Acute physical exercise and long-term individual shear rate therapy increase telomerase activity in human peripheral blood mononuclear cells.
Zietzer, A., Buschmann, E.E., Janke, D., Li, L., Brix, M., Meyborg, H., Stawowy, P., Jungk, C., Buschmann, I. and Hillmeister, P.
Acta Physiologica 220
(5): 251-262.
June 2017
Guidelines on severity assessment and classification of genetically altered mouse and rat lines.
Zintzsch, A., Noe, E., Reissmann, M., Ullmann, K., Kraemer, S., Jerchow, B., Kluge, R., Goesele, C., Nickles, H., Puppe, A. and Ruelicke, T.
Laboratory Animals 51
(6): 573-582.
1 December 2017
Synthesis of europium-doped VSOP, customized enhancer solution and improved microscopy fluorescence methodology for unambiguous histological detection.
de Schellenberger, A.A., Hauptmann, R., Millward, J.M., Schellenberger, E., Kobayashi, Y., Taupitz, M., Infante-Duarte, C., Schnorr, J. and Wagner, S.
Journal of Nanobiotechnology 15
(1): 71.
10 October 2017
The role of de novo mutations in the development of amyotrophic lateral sclerosis.
van Doormaal, P.T.C., Ticozzi, N., Weishaupt, J.H., Kenna, K., Diekstra, F.P., Verde, F., Andersen, P.M., Dekker, A.M, Tiloca, C., Marroquin, N., Overste, D.J., Pensato, V., Nürnberg, P., Pulit, S.L., Schellevis, R.D., Calini, D., Altmüller, J., Francioli, L.C., Muller, B., Castellotti, B., Motameny, S., Ratti, A., Wolf, J., Gellera, C., Ludolph, A.C., van den Berg, L.H., Kubisch, C., Landers, J.E., Veldink, J.H., Silani, V. and Volk, A.E.
Human Mutation 38
(11): 1534-1541.
November 2017
Brain renin-angiotensin system: does it exist?
van Thiel, B.S., Góes Martini, A., Te Riet, L., Severs, D., Uijl, E., Garrelds, I.M., Leijten, F.P.J., van der Pluijm, I., Essers, J., Qadri, F., Alenina, N., Bader, M., Paulis, L., Rajkovicova, R., Domenig, O., Poglitsch, M. and Danser, A.H.J.
Hypertension 69
(6): 1136-1144.
June 2017
Angiotensin II responsiveness after preeclampsia: translational data from an experimental rat model and early-onset human preeclampsia.
van der Graaf, A.M., Toering, T.J., van der Wiel, M.W.K., Frenay, A.R.S., Wallukat, G., Dechend, R., Navis, G., Groen, H., Lely, A.T. and Faas, M.M.
Journal of Hypertension 35
(12): 2468-2478.
December 2017
Representation of cardiovascular magnetic resonance in the AHA / ACC guidelines.
von Knobelsdorff-Brenkenhoff, F., Pilz, G. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 19
(1): 70.
25 September 2017
Detection and monitoring of acute myocarditis applying quantitative cardiovascular magnetic resonance.
von Knobelsdorff-Brenkenhoff, F., Schüler, J., Doganguezel, S., Dieringer, M.A., Rudolph, A., Greiser, A., Kellman, P. and Schulz-Menger, J.
Circulation Cardiovascular Imaging 10
(2): e005242.
February 2017
ANGPTL8 (betatrophin) is expressed in visceral adipose tissue and relates to human hepatic steatosis in two independent clinical collectives.
von Loeffelholz, C., Pfeiffer, A.F.H., Lock, J.F., Lieske, S., Döcke, S., Murahovschi, V., Kriebel, J., de Las Heras Gala, T., Grallert, H., Rudovich, N., Stockmann, M., Spranger, J., Jahreis, G., Bornstein, S.R., Lau, G., Xu, A., Schulz-Menger, J., Exner, L., Haufe, S., Jordan, J., Engeli, S. and Birkenfeld, A.L.
Hormone and Metabolic Research 49
(5): 343-349.
May 2017
Book Section
Polymer models of the chromosomes in the nucleus of cells.
Chiariello, A.M., Bianco, S., Piccolo, A., Annunziatella, C., Barbieri, M., Pombo, A. and Nicodemi, M.
In:
High Performance Scientific Computing Using Distributed Infrastructures.
World Scientific Publishing Co., 239-248.
ISBN 9789814759700
January 2017
Essentials of miRNA-dependent control of mRNA translation and decay, miRNA targeting principles, and methods for target identification.
Grosswendt, S. and Rajewsky, N.
In:
Essentials of noncoding RNA in neuroscience: ontogenetics, plasticity of the vertebrate brain.
Academic Press, London, 19-38.
ISBN 978-012804402-5
2017
Is signaling specificity encoded in arrestin conformation?
Hoffmann, C., Lohse, M.J. and Luttrell, L.M.
In:
The Structural Basis of Arrestin Functions.
Springer, Cham, Switzerland, 235-253.
ISBN 978-3-319-57552-0
25 May 2017
Transposase.
Izsvák, Z. and Ivics, Z.
In:
Reference Module in Life Sciences.
Elsevier, 161-164.
ISBN 978-0-12-809633-8
16 March 2017
Resolution in electron tomography.
Kudryashev, M.
In:
Cellular Imaging.
Biological and Medical Physics, Biomedical Engineering
.
Springer, Cham, Switzerland, 261–282.
ISBN 978-3-319-68995-1
31 December 2017
MACC1, a novel player in solid cancer carcinogenesis.
Mudduluru, G., Ilm, K., Dahlmann, M. and Stein, U.
In:
Mechanisms of Molecular Carcinogenesis - Volume 1.
Springer, Cham, 11-38.
ISBN 978-3-319-53657-6
2017
On the nature of chromatin 3D organization.
Nicodemi, M. and Pombo, A.
In:
Epigenetics and Systems Biology.
Academic Press, 191-201.
ISBN 978-012803075-2
2017
INSERT Project: First results of a MR compatible preclinical SPECT based on SiPM photodetectors.
Occhipinti, M., Busca, P., Carminati, M., Fiorini, C., Montagnani, G.L., Nagy, K., Legradi, G., Bukki, T., Nyitrai, Z., Papp, Z., Nagy, A., Kuehne, A., Niendorf, T. and Piemonte, C.
In:
2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD).
IEEE, 1-4.
ISBN 978-1-5090-1642-6
2017
Pharmacological approaches for delineating functions of AKAP- based signalling complexes and finding therapeutic targets.
Schrade, K. and Klussmann, E.
In:
Microdomains in the Cardiovascular System.
Cardiac and Vascular Biology
.
Springer, Cham, Switzerland, 59-83.
ISBN 978-3-319-54578-3
20 September 2017
Förster resonance energy transfer to study TCR-pMHC interactions in the immunological synapse.
Schütz, G.J. and Huppa, J.B.
In:
The immune synapse.
Methods in Molecular Biology, 1584
.
Springer Nature, New York, NY, USA, 207-229.
ISBN 978-1-4939-8327-8
3 March 2017
PcG proteins in caenorhabditis elegans.
Tursun, B.
In:
Polycomb Group Proteins.
Translational Epigenetics Series
.
Elsevier / Academic Press, Amsterdam, 289-315.
ISBN 978-0-12-809737-3
6 January 2017
Conference or Workshop Item
Sparse control of force field dynamics.
Bongini, M., Fornasier, M., Fröhlich, F. and Haghverdi, L.
In: 7th International Conference on NETwork Games, COntrol and OPtimization (NetGCoop), 29 - 31 Oct 2014, Trento, Italy.
8 June 2017
Tissue optical properties from spatially resolved reflectance: calibration and in vivo application on rat kidney.
Gladytz, T., Hoppe, A., Cantow, K., Flemming, B., Pohlmann, A., Niendorf, T., Seeliger, E. and Grosenick, D.
In: European Conferences on Biomedical Optics 2017, 25-27 Jun 2017, Munich, Germany.
28 July 2017
Reliable determination of tissue optical properties from spatially resolved reflectance.
Gladytz, T., Hoppe, A., Cantow, K., Pohlmann, A., Flemming, B., Niendorf, T., Seeliger, E. and Grosenick, D.
In: SPIE BiOS, 2017, San Francisco, California, United States.
14 March 2017
Was ist in der Medizin moeglich: Neue Therapien.
Lohse, M.
In: Medizin 4.0 - Zur Zukunft der digitalisierten Welt. IV. Interdisziplinaerer Kongress Berlin 2016 mit der Heinz Nixdorf-Stiftung - gemeinsam mit der Charite - Universitaetsmedizin Berlin, 1-2 June 2016, Berlin, Germany.
2017
Radiative RF antenna arrays for cardiac, brain and thermal magnetic resonance at ultrahigh and extreme magnetic field strengths: Concepts, electromagnetic field simulations and applications.
Niendorf, T., Oezerdem, C., Ji, Y., Oberacker, E., Kuehne, A., Waiczies, H. and Winter, L.
In: International Conference on Electromagnetics in Advanced Applications (ICEAA), 11-15 Sept 2017, Verona, Italy.
2017
Crowd sourcing image segmentation with iaSTAPLE.
Schlesinger, D., Jug, F., Myers, G., Rother, C. and Kainmueller, D.
In: 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017), 18-21 Apr 2017, Melbourne, VIC, Australia.
19 June 2017
A study of Lagrangean decompositions and dual ascent solvers for graph matching.
Swoboda, P., Rother, C., Alhaija, H.A., Kainmüller, D. and Savchynskyy, B.
In: 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), 21-26 Jul 2017, Honolulu, HI, USA.
9 November 2017
Book
Plant epigenetics.
Rajewsky, N., Jurga, S. and Barciszewski, J., eds.
RNA Technologies
.
Springer, Cham.
ISBN 978-3-319-55519-5
2017
Review
Pancreatic cancer models for translational research.
Behrens, D., Walther, W. and Fichtner, I.
Pharmacology & Therapeutics 173
: 146-158.
May 2017
Kardiomyopathien bei Muskeldystrophien [Cardiomyopathy in muscular dystrophies].
Blaszczyk, E., Perrot, A., Schmacht, L., Lim, C., Spuler, S. and Schulz-Menger, J.
Aktuelle Kardiologie 6
(06): 454-460.
2017
Transcriptional mechanisms coordinating tight junction assembly during epithelial differentiation.
Boivin, F.J. and Schmidt-Ott, K.
Annals of the New York Academy of Sciences 1397
(1): 80-99.
June 2017
Untersuchungen des visuellen Systems in der Neurologie: aktuelle Forschung und klinische Relevanz [Investigation of the visual system in neurology: Current research and clinical relevance].
Brandt, A., Zimmermann, H., Scheel, M., Finke, C., Albrecht, P. and Paul, F.
Aktuelle Neurologie 44
(1): 27-45.
2017
Genomics of acute myeloid leukemia diagnosis and pathways.
Bullinger, L., Döhner, K. and Döhner, H.
Journal of Clinical Oncology 35
(9): 934-946.
20 March 2017
Beyond read-counts: Ribo-seq data analysis to understand the functions of the transcriptome.
Calviello, L. and Ohler, U.
Trends in Genetics 33
(10): 728-744.
October 2017
Role of vitamin A/retinoic acid in regulation of embryonic and adult hematopoiesis.
Canete, A., Cano, E., Munoz-Chapuli, R. and Carmona, R.
Nutrients 9
(2): 159.
20 February 2017
A life course examination of the physical environmental determinants of physical activity behaviour: A "Determinants of Diet and Physical Activity" (DEDIPAC) umbrella systematic literature review.
Carlin, A., Perchoux, C., Puggina, A., Aleksovska, K., Buck, C., Burns, C., Cardon, G., Chantal, S., Ciarapica, D., Condello, G., Coppinger, T., Cortis, C., D'Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Kennedy, A., Lakerveld, J., Chun Man Ling, F., Luzak, A., Napolitano, G., Nazare, J.A., Pischon, T., Polito, A., Sannella, A., Schulz, H., Sohun, R., Steinbrecher, A., Schlicht, W., Ricciardi, W., MacDonncha, C., Capranica, L. and Boccia, S.
PLoS ONE 12
(8): e0182083.
7 August 2017
Interrogating islets in health and disease with single-cell technologies.
Carrano, A.C., Mulas, F., Zeng, C. and Sander, M.
Molecular Metabolism 6
(9): 991-1001.
September 2017
A polymer physics investigation of the architecture of the murine orthologue of the 7q11.23 human locus.
Chiariello, A.M., Esposito, A., Annunziatella, C., Bianco, S., Fiorillo, L., Prisco, A. and Nicodemi, M.
Frontiers in Neuroscience 11
: 559.
10 October 2017
Behavioral determinants of physical activity across the life course: a "DEterminants of DIet and Physical ACtivity" (DEDIPAC) umbrella systematic literature review.
Condello, G., Puggina, A., Aleksovska, K., Buck, C., Burns, C., Cardon, G., Carlin, A., Simon, C., Ciarapica, D., Coppinger, T., Cortis, C., D'Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Kennedy, Ai., Ling, F.C.M., Luzak, A., Napolitano, G., Nazare, J.-A., Perchoux, C., Pesce, C., Pischon, T., Polito, A., Sannella, A., Schulz, H., Sohun, R., Steinbrecher, A., Schlicht, W., Ricciardi, W., MacDonncha, C., Capranica, L. and Boccia, S.
International Journal of Behavioral Nutrition and Physical Activity 14
(1): 58.
2 May 2017
Psychological determinants of physical activity across the life course: a "determinants of diet and physical activity" (DEDIPAC) umbrella systematic literature review.
Cortis, C., Puggina, A., Pesce, C., Aleksovska, K., Buck, C., Burns, C., Cardon, G., Carlin, A., Simon, C., Ciarapica, D., Condello, G., Coppinger, T., D'Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Kennedy, A., Ling, F.C.M., Luzak, A., Napolitano, G., Nazare, J.A., O'Donoghue, G., Perchoux, C., Pischon, T., Polito, A., Sannella, A., Schulz, H., Sohun, R., Steinbrecher, A., Schlicht, W., Ricciardi, W., Castellani, L., MacDonncha, C., Capranica, L. and Boccia, S.
PLoS ONE 12
(8): e0182709.
17 August 2017
Functional insights into pathogen biology from 3D electron microscopy.
Cyrklaff, M., Frischknecht, F. and Kudryashev, M.
FEMS Microbiology Reviews 41
(6): 828-853.
1 November 2017
Targeted basic research to highlight the role of estrogen and estrogen receptors in the cardiovascular system.
Dworatzek, E. and Mahmoodzadeh, S.
Pharmacological Research 119
: 27-35.
May 2017
Proton electrochemical gradient: driving and regulating neurotransmitter uptake.
Farsi, Z., Jahn, R. and Woehler, A.
BioEssays 39
(5): 1600240.
May 2017
Hypertension and risk of post-operative cognitive dysfunction (POCD): a systematic review and meta-analysis.
Feinkohl, I., Winterer, G. and Pischon, T.
Clinical Practice and Epidemiology in Mental Health 13
: 27-42.
18 May 2017
Is there a sex-shift in prevalence of allergic rhinitis and comorbid asthma from childhood to adulthood? A meta-analysis.
Froehlich, M., Pinart, M., Keller, T., Reich, A., Cabieses, B., Hohmann, C., Postma, D.S., Bousquet, J., Anto, J.M., Keil, T. and Roll, S.
Clinical and Translational Allergy 7
: 44.
5 December 2017
Molecular definitions of autophagy and related processes.
Galluzzi, L., Baehrecke, E.H., Ballabio, A., Boya, P., Bravo-San Pedro, J.M., Cecconi, F., Choi, A.M., Chu, C.T., Codogno, P., Colombo, M.I., Cuervo, A.M., Debnath, J., Deretic, V., Dikic, I., Eskelinen, E.L., Fimia, G.M., Fulda, S., Gewirtz, D.A., Green, D.R., Hansen, M., Harper, J.W., Jäättelä, M., Johansen, T., Juhasz, G., Kimmelman, A.C., Kraft, C., Ktistakis, N.T., Kumar, S., Levine, B., Lopez-Otin, C., Madeo, F., Martens, S., Martinez, J., Melendez, A., Mizushima, N., Münz, C., Murphy, L.O., Penninger, J.M., Piacentini, M., Reggiori, F., Rubinsztein, D.C., Ryan, K.M., Santambrogio, L., Scorrano, L., Simon, A.K., Simon, H.U., Simonsen, A., Tavernarakis, N., Tooze, S.A., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q. and Kroemer, G.
EMBO Journal 36
(13): 1811-1836.
3 July 2017
Adipose-vascular coupling and potential therapeutics.
Gollasch, M.
Annual Review of Pharmacology and Toxicology 57
: 417-436.
January 2017
RNA-based recognition and targeting: sowing the seeds of specificity.
Gorski, S.A., Vogel, J. and Doudna, J.A.
Nature Reviews Molecular Cell Biology 18
(4): 215-228.
April 2017
Epigenetics of cell fate reprogramming and its implications for neurological disorders modelling.
Grzybek, M., Golonko, A., Walczak, M. and Lisowski, P.
Neurobiology of Disease 99
: 84-120.
March 2017
The dorsal spinal cord and hindbrain: from developmental mechanisms to functional circuits.
Hernandez-Miranda, L.R., Müller, T. and Birchmeier, C.
Developmental Biology 432
(1): 34-42.
1 December 2017
Wide awake and ready to move: 20 years of non-viral therapeutic genome engineering with the Sleeping Beauty transposon system.
Hodge, R., Narayanavari, S., Izsvák, Z. and Ivics, Z.
Human Gene Therapy 28
(10): 842-855.
1 October 2017
Going non-viral: the Sleeping Beauty transposon system breaks on through to the clinical side.
Hudecek, M., Izsvák, Z., Johnen, S., Renner, M., Thumann, G. and Ivics, Z.
Critical Reviews in Biochemistry and Molecular Biology 52
(4): 355-380.
August 2017
Concise review: Induced pluripotent stem cell-based drug discovery for mitochondrial disease.
Inak, G., Lorenz, C., Lisowski, P., Zink, A., Mlody, B. and Prigione, A.
Stem Cells 35
(7): 1655-1662.
July 2017
Socio-cultural determinants of physical activity across the life course: a 'Determinants of Diet and Physical Activity' (DEDIPAC) umbrella systematic literature review.
Jaeschke, L., Steinbrecher, A., Luzak, A., Puggina, A., Aleksovska, K., Buck, C., Burns, C., Cardon, G., Carlin, A., Chantal, S., Ciarapica, D., Condello, G., Coppinger, T., Cortis, C., De Craemer, M., D'Haese, S., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Kanning, M., Kennedy, A., Ling, F.C.M., Napolitano, G., Nazare, J.A., Perchoux, C., Polito, A., Ricciardi, W., Sannella, A., Schlicht, W., Sohun, R., MacDonncha, C., Boccia, S., Capranica, L., Schulz, H. and Pischon, T.
International Journal of Behavioral Nutrition and Physical Activity 14
(1): 173.
20 December 2017
Engineering kidney cells: reprogramming and directed differentiation to renal tissues.
Kaminski, M.M., Tosic, J., Pichler, R., Arnold, S.J. and Lienkamp, S.S.
Cell and Tissue Research 369
(1): 185-197.
July 2017
Gene therapy with the Sleeping Beauty transposon system.
Kebriaei, P., Izsvák, Z., Narayanavari, S.A., Singh, H. and Ivics, Z.
Trends in Genetics 33
(11): 852-870.
November 2017
Structural-functional features of the thyrotropin receptor: a class A G-protein-coupled receptor at work.
Kleinau, G., Worth, C.L., Kreuchwig, A., Biebermann, H., Marcinkowski, P., Scheerer, P. and Krause, G.
Frontiers in Endocrinology 8
: 86.
24 April 2017
Choosing wisely - Preclinical test models in the era of precision medicine.
Klinghammer, K., Walther, W. and Hoffmann, J.
Cancer Treatment Reviews 55
: 36-45.
April 2017
Vitamin D in the prevention, prediction and treatment of neurodegenerative and neuroinflammatory diseases.
Koduah, P., Paul, F. and Dörr, J.M.
EPMA Journal 8
(4): 313-325.
December 2017
Diffusion tensor imaging for multilevel assessment of the visual pathway: possibilities for personalized outcome prediction in autoimmune disorders of the central nervous system.
Kuchling, J., Brandt, A.U., Paul, F. and Scheel, M.
EPMA Journal 8
(3): 279-294.
September 2017
T cell receptors for clinical therapy: in vitro assessment of toxicity risk.
Kunert, A., Obenaus, M., Lamers, C.H.J., Blankenstein, T. and Debets, R.
Clinical Cancer Research 23
(20): 6012-6020.
15 October 2017
Mitochondrial metabolism in early neural fate and its relevance for neuronal disease modeling.
Lorenz, C. and Prigione, A.
Current Opinion in Cell Biology 49
: 71-76.
December 2017
Renoprotection: focus on TRPV1, TRPV4, TRPC6 and TRPM2.
Markó, L., Mannaa, M., Haschler, T.N., Krämer, S. and Gollasch, M.
Acta Physiologica 219
(3): 589-612.
March 2017
Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.
Medina-Ramírez, M., Sanders, R.W. and Sattentau, Q.J.
Current Opinion in HIV and AIDS 12
(3): 241-249.
May 2017
Physical exercise on inflammatory markers in type 2 diabetes patients: a systematic review of randomized controlled trials.
Melo, L.C., Dativo-Medeiros, J., Menezes-Silva, C.E., Barbosa, F.T., de Sousa-Rodrigues, C.. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2017
(2017): 8523728.
19 March 2017
Degrons in cancer.
Meszaros, B., Kumar, M., Gibson, T.J., Uyar, B. and Dosztanyi, Z.
Science Signaling 10
(470): eaak9982.
14 March 2017
Sleeping Beauty transposition: from biology to applications.
Narayanavari, S.A., Chilkunda, S.S., Ivics, Z. and Izsvák, Z.
Critical Reviews in Biochemistry and Molecular Biology 52
(1): 18-44.
January 2017
Sleeping Beauty transposon vectors for therapeutic applications: advances and challenges.
Narayanavari, S.A. and Izsvák, Z.
Cell and Gene Therapy Insights 3
(2): 131-158.
30 March 2017
Underlying mechanisms for distant metastasis - molecular biology.
Pachmayr, E., Treese, C. and Stein, U.
Visceral Medicine 33
(1): 11-20.
February 2017
Fatigue as a symptom or comorbidity of neurological diseases.
Penner, I.K. and Paul, F.
Nature Reviews Neurology 13
(11): 662-675.
November 2017
Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis.
Petzold, A., Balcer, L.J., Calabresi, P.A., Costello, F., Frohman, T.C., Frohman, E.M., Martinez-Lapiscina, E.H., Green, A.J., Kardon, R., Outteryck, O., Paul, F., Schippling, S., Vermersch, P., Villoslada, P. and Balk, L.J.
Lancet Neurology 16
(10): 797-812.
October 2017
The link between angiogenesis and endothelial metabolism.
Potente, M. and Carmeliet, P.
Annual Review of Physiology 79
: 43-66.
10 February 2017
Vascular heterogeneity and specialization in development and disease.
Potente, M. and Mäkinen, T.
Nature Reviews Molecular Cell Biology 18
(8): 477-494.
August 2017
Tissue specific labeling in proteomics.
Ramberger, E. and Dittmar, G.
Proteomes 5
(3): E17.
18 July 2017
Renin-angiotensin system in diabetes.
Rein, J. and Bader, M.
Protein and Peptide Letters 24
(9): 833-840.
17 November 2017
Mechanistic roles of autophagy in hematopoietic differentiation.
Riffelmacher, T. and Simon, A.K.
FEBS Journal 284
(7): 1008-1020.
April 2017
Childhood cancer predisposition syndromes - a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.
Ripperger, T., Bielack, S.S., Borkhardt, A., Brecht, I.B., Burkhardt, B., Calaminus, G., Debatin, K.M., Deubzer, H., Dirksen, U., Eckert, C., Eggert, A., Erlacher, M., Fleischhack, G., Frühwald, M.C., Gnekow, A., Goehring, G., Graf, N., Hanenberg, H., Hauer, J., Hero, B., Hettmer, S., von Hoff, K., Horstmann, M., Hoyer, J., Illig, T., Kaatsch, P., Kappler, R., Kerl, K., Klingebiel, T., Kontny, U., Kordes, U., Körholz, D., Koscielniak, E., Kramm, C.M., Kuhlen, M., Kulozik, A.E., Lamottke, B., Leuschner, I., Lohmann, D.R., Meinhardt, A., Metzler, M., Meyer, L.H., Moser, O., Nathrath, M., Niemeyer, C.M., Nustede, R., Pajtler, K.W., Paret, C., Rasche, M., Reinhardt, D., Rieß, O., Russo, A., Rutkowski, S., Schlegelberger, B., Schneider, D., Schneppenheim, R., Schrappe, M., Schroeder, C., von Schweinitz, D., Simon, T., Sparber-Sauer, M., Spix, C., Stanulla, M., Steinemann, D., Strahm, B., Temming, P., Thomay, K., von Bueren, A.O., Vorwerk, P., Witt, O., Wlodarski, M., Wössmann, W., Zenker, M., Zimmermann, S., Pfister, S.M. and Kratz, C.P.
American Journal of Medical Genetics Part A 173
(4): 1017-1037.
April 2017
Optogenetic tools for subcellular applications in neuroscience.
Rost, B.R., Schneider-Warme, F., Schmitz, D. and Hegemann, Peter
Neuron 96
(3): 572-603.
1 November 2017
Survival and cardiovascular outcomes of patients with secondary mitral regurgitation: a systematic review and meta-analysis.
Sannino, A., Smith, R.L., Schiattarella, G.G., Trimarco, B., Esposito, G. and Grayburn, P.A.
JAMA Cardiology 2
(10): 1130-1139.
1 October 2017
Health-beneficial nutraceuticals - myth or reality?
Sauer, S. and Plauth, A.
Applied Microbiology and Biotechnology 101
(3): 951-961.
February 2017
Elementary immunology: Na(+) as a regulator of immunity.
Schatz, V., Neubert, P., Schröder, A., Binger, K., Gebhard, M., Müller, D.N., Luft, F.C., Titze, J. and Jantsch, J.
Pediatric Nephrology 32
(2): 201-210.
February 2017
Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis.
Schiattarella, G.G., Sannino, A., Toscano, E., Giugliano, G., Gargiulo, G., Franzone, A., Trimarco, B., Esposito, G. and Perrino, C.
European Heart Journal 38
(39): 2948-2956.
14 October 2017
Sorting receptor SORLA: cellular mechanisms and implications for disease.
Schmidt, V., Subkhangulova, A. and Willnow, T.E.
Cellular and Molecular Life Sciences 74
(8): 1475-1483.
April 2017
How to grow a kidney: patient-specific kidney organoids come of age.
Schmidt-Ott, K.M.
Nephrology Dialysis Transplantation 32
(1): 17-23.
January 2017
Biomarkers in acute kidney injury - pathophysiological basis and clinical performance.
Schrezenmeier, E.V., Barasch, J., Budde, K., Westhoff, T. and Schmidt-Ott, K.M.
Acta Physiologica 219
(3): 554-572.
March 2017
Myopathology in the times of modern genetics.
Schuelke, M., Oien, N.C. and Oldfors, A.
Neuropathology and Applied Neurobiology 43
(1): 44-61.
February 2017
Novel treatment options in head and neck cancer.
Schuler, P.J., Laban, S., Doescher, J., Bullinger, L. and Hoffmann, T.K.
Oncology Research and Treatment 40
(6): 342-346.
June 2017
Methods for lineage tracing on the organism-wide level.
Spanjaard, B. and Junker, J.P.
Current Opinion in Cell Biology 49
: 16-21.
December 2017
Speculations on salt and the genesis of arterial hypertension.
Titze, Jens and Luft, F.C.
Kidney International 91
(6): 1324-1335.
June 2017
Sex in basic research: concepts in the cardiovascular field.
Ventura-Clapier, R., Dworatzek, E., Seeland, U., Kararigas, G., Arnal, J.F., Brunelleschi, S., Carpenter, T.C., Erdmann, J., Franconi, F., Giannetta, E., Glezerman, M., Hofmann, S.M., Junien, C., Katai, M., Kublickiene, K., Koenig, I.R., Majdic, G., Malorni, W., Mieth, C., Miller, V.M., Reynolds, R.M., Shimokawa, H., Tannenbaum, C., D'Ursi, A.M. and Regitz-Zagrosek, V.
Cardiovascular Research 113
(7): 711-724.
June 2017
Endocytic receptor LRP2/megalin-of holoprosencephaly and renal Fanconi syndrome.
Willnow, T.E. and Christ, A.
Pflugers Archiv 469
(7-8): 907-916.
August 2017
Microglia in physiology and disease.
Wolf, S.A., Boddeke, H.W.G.M. and Kettenmann, H.
Annual Review of Physiology 79
: 619-643.
February 2017
You need guts to make new neurons.
Wolf, S.A. and Mattei, D.
Current Behavioral Neuroscience Reports 4
(4): 353-360.
December 2017
Approaches and techniques to characterize cancer metabolism in vitro and in vivo.
Zaimenko, I., Lisec, J., Stein, U. and Brenner, W.
Biochimica et Biophysica Acta - Reviews on Cancer 1868
(2): 412-419.
December 2017
Optische Kohaerenztomografie in der Neurologie: Methodik und Anwendung in Forschung und Klinik [Optical coherence tomography in neurology: method and application in research and clinical routine].
Zimmermann, H.G., Brandt, A.U. and Paul, F.
Klinische Neurophysiologie 48
(4): 211-225.
December 2017
Letter
Gene expression analysis of decitabine treated AML: high impact of tumor suppressor gene expression changes.
Bohl, S.R., Dolnik, A., Jensen, T., Lang, K.M., Hackanson, B., Gaidzik, V.I., Paschka, P., Knudsen, S., Döhner, K., Döhner, H., Claus, R., Lübbert, M. and Bullinger, L.
Leukemia & Lymphoma 58
(9): 2264-2267.
2 September 2017
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Ferreira, M.A., Vonk, J.M., Baurecht, H., Marenholz, I., Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, V., van Dongen, J., Lu, Yi, Rueschendorf, F., Esparza-Gordillo, J., Medway, C.W., Mountjoy, E., Burrows, K., Hummel, O., Grosche, S., Brumpton, B.M., Witte, J.S., Hottenga, J.J., Willemsen, G., Zheng, J., Rodriguez, E., Hotze, M., Franke, A., Revez, J.A., Beesley, J., Matheson, M.C., Dharmage, S.C., Bain, L.M., Fritsche, L.G., Gabrielsen, M.E., Balliu, B., Nielsen, J.B., Zhou, W., Hveem, K., Langhammer, A., Holmen, O.L., Løset, M., Abecasis, G.R., Willer, C.J., Arnold, A., Homuth, G., Schmidt, C.O., Thompson, P.J., Martin, N.G., Duffy, D.L., Novak, N., Schulz, H., Karrasch, S., Gieger, C., Strauch, K., Melles, R.B., Hinds, D.A., Hübner, N., Weidinger, S., Magnusson, P.K.E., Jansen, R., Jorgenson, E., Lee, Y.A., Boomsma, D.I., Almqvist, C., Karlsson, R., Koppelman, G.H. and Paternoster, L.
Nature Genetics 49
(12): 1752-1757.
December 2017
Acute myeloid leukemia with mutated nucleophosmin 1: an immunogenic acute myeloid leukemia subtype and potential candidate for immune checkpoint inhibition.
Greiner, J., Hofmann, S., Schmitt, M., Götz, M., Wiesneth, M., Schrezenmeier, H., Bunjes, D., Döhner, H. and Bullinger, L.
Haematologica 102
(12): e499-e501.
December 2017
Incidence and prognostic impact of ASXL2 mutations in adult acute myeloid leukemia patients with t(8;21)(q22;q22): a study of the German-Austrian AML Study Group.
Jahn, N., Agrawal, M., Bullinger, L., Weber, D., Corbacioglu, A., Gaidzik, V.I., Schmalbrock, L., Thol, F., Heuser, M., Krauter, J., Göhring, G., Kündgen, A., Fiedler, W., Wattad, M., Held, G., Köhne, C.H., Horst, H.A., Lübbert, M., Ganser, A., Schlenk, R.F., Döhner, H., Döhner, K. and Paschka, P.
Leukemia 31
(4): 1012-1015.
April 2017
Prescribing behavior is a cause.
Luft, F.C.
Deutsches Arzteblatt International 114
(26): 462.
30 June 2017
Metatarsal bony syndactyly in 2 fetuses with Smith-Lemli-Opitz syndrome: An under-recognized part of the clinical spectrum.
Moosa, S., Loeys, B., Altmüller, J., Mortier, G., Nürnberg, P., Li, Y., Wollnik, B. and Vogel, I.
Clinical Genetics 92
(3): 342-343.
September 2017
Histopathologic assessment of neurotoxicity after repeated administration of gadodiamide in healthy rats.
Schlemm, L., Radbruch, H., Brandt, A.U., Scheel, M. and Paul, F.
Radiology 282
(3): 925-926.
March 2017
Confounding in ex vivo models of Diamond-Blackfan anemia.
Ulirsch, J.C., Lareau, C., Ludwig, L.S., Mohandas, N., Nathan, D.G. and Sankaran, V.G.
Blood 130
(9): 1165-1168.
31 August 2017
Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations.
van den Brink, S.C., Sage, F., Vertesy, A., Spanjaard, B., Peterson-Maduro, J., Baron, C.S., Robin, C. and van Oudenaarden, A.
Nature Methods 14
(10): 935-936.
29 September 2017
Editorial
New Q(ues) to keep blood vessels growing.
Andrade, J. and Potente, M.
EMBO Journal 36
(16): 2315-2317.
15 August 2017
Of mice and renin.
Bader, M.
Hypertension 70
(1): 35-37.
July 2017
Enhanced precision and efficiency.
Bashir, S. and Kühn, R.
Nature Biomedical Engineering 1
(11): 856-857.
November 2017
Cell cycle: continuous chromatin changes.
Beagrie, R.A. and Pombo, A.
Nature 547
(7661): 34-35.
6 July 2017
Keep them close: PRC2 poises enhancer-promoter interactions at anterior neuronal genes.
Caglio, Giulia, Torlai Triglia, E. and Pombo, A.
Cell Stem Cell 20
(5): 573-575.
4 May 2017
Pericytes or mesenchymal stem cells: is that the question?
Cano, E., Gebala, V. and Gerhardt, H.
Cell Stem Cell 20
(3): 296-297.
2 March 2017
Mitochondrial homeostasis: How do dimers of mitofusins mediate mitochondrial fusion?
Daumke, O. and Roux, A.
Current Biology 27
(9): R353-R356.
8 May 2017
Deciphering the ubiquitin code.
Dittmar, G. and Selbach, M.
Molecular Cell 65
(5): 779-780.
2 March 2017
Life is change - dynamic modeling quantifies it.
Falcke, M.
Current Opinion in Systems Biology 3
: iv-viii.
June 2017
Morph or move? How distinct endothelial cell responses to blood flow shape vascular networks.
Franco, C.A. and Gerhardt, H.
Developmental Cell 41
(6): 574-576.
19 June 2017
Nephrologische Gendiagnostik in der klinischen Routine [Nephrological gene diagnostics in clinical routine].
Gollasch, M.
Nieren- und Hochdruckkrankheiten 46
(7): 281-282.
July 2017
Comeback of the rat in biomedical research.
Homberg, J.R., Woehr, M. and Alenina, N.
ACS Chemical Neuroscience 8
(5): 900-903.
17 May 2017
Targeting HDAC3 in CREBBP-mutant lymphomas counterstrikes unopposed enhancer deacetylation of B-cell signaling and immune response genes.
Höpken, U.E.
Cancer Discovery 7
(1): 14-16.
January 2017
Introduction: Special issue in honor of Bruce Ransom.
Kettenmann, H.
Neurochemical Research 42
(9): 2437-2441.
September 2017
Vasculitis: a CLEAR argument for targeting complement in ANCA vasculitis.
Kettritz, R.
Nature Reviews Nephrology 13
(8): 448-450.
August 2017
The case: acid-base diagnoses in the 21st century.
Kettritz, R., Ritter, T., Rudolph, B. and Luft, F.C.
Kidney International 92
(5): 1293-1294.
November 2017
Redox homeostasis: unlocking the bottleneck in glia-to-neuron conversion.
Klempin, F., Gertz, K. and Kronenberg, G.
Stem Cell Investigation 4
: 7.
9 February 2017
Master and commander? FoxO's role in muscle atrophy.
Langer, H.T.
Journal of Physiology 595
(14): 4593-4594.
15 July 2017
Building bridges through science.
Lissek, T., Adams, M., Adelman, J., Ahissar, E., Akaaboune, M., Akil, H., al'Absi, M., Arain, F., Arango-Lasprilla, J.C., Atasoy, D., Avila, J., Badawi, A., Bading, H., Baig, A.M., Baleriola, J., Belmonte, C., Bertocchi, I., Betz, H., Blakemore, C., Blanke, O., Boehm-Sturm, P., Bonhoeffer, T., Bonifazi, P., Brose, N., Campolongo, P., Celikel, T., Chang, C.C., Chang, T.Y., Citri, A., Cline, H.T., Cortes, J.M., Cullen, K., Dean, K., Delgado-Garcia, J.M., Desroches, M., Disterhoft, J.F., Dowling, J.E., Draguhn, A., El-Khamisy, S.F., El Manira, A., Enam, S.A., Encinas, J.M., Erramuzpe, A., Esteban, J.A., Fariñas, I., Fischer, E., Fukunaga, I., Gabilondo, I., Ganten, D., Gidon, A., Gomez-Esteban, J.C., Greengard, P., Grinevich, V., Gruart, A., Guillemin, R., Hariri, A.R., Hassan, B., Haeusser, M., Hayashi, Y., Hussain, N.K., Jabbar, A.A., Jaber, M., Jahn, R., Janahi, E.M., Kabbaj, M., Kettenmann, H., Kindt, M., Knafo, S., Köhr, G., Komai, S., Krugers, H., Kuhn, B., Ghazal, N.L., Larkum, M.E., London, M., Lutz, B., Matute, C., Martinez-Millan, L., Maroun, M., McGaugh, J., Moustafa, A.A., Nasim, A., Nave, K.A., Neher, E., Nikolich, K., Outeiro, T., Palmer, L.M., Penagarikano, O., Perez-Otano, I., Pfaff, D.W., Poucet, B., Rahman, A.U., Ramos-Cabrer, P., Rashidy-Pour, A., Roberts, R.J., Rodrigues, S., Sanes, J.R., Schaefer, A.T., Segal, M., Segev, I., Shafqat, S., Siddiqui, N.A., Soreq, H., Soriano-Garcia, E., Spanagel, R., Sprengel, R., Stuart, G., Südhof, T.C., Tønnesen, J., Treviño, M., Uthman, B.M., Venter, J.C., Verkhratsky, A., Weiss, C., Wiesel, T.N., Yaksi, E., Yizhar, O., Young, L.J., Young, P., Zawia, N.H., Zugaza, J.L. and Hasan, M.T.
Neuron 96
(4): 730-735.
15 November 2017
Defensins defend against bone loss.
Luft, F.C.
Journal of Molecular Medicine 95
(12): 1255-1256.
December 2017
Cystic fibrosis: the conductance regulator, ceramides, and possible treatments.
Luft, F.C.
Journal of Molecular Medicine 95
(10): 1017-1019.
October 2017
The promise of stromal cell-derived factor-1 in novel heart disease treatments.
Luft, F.C.
Journal of Molecular Medicine 95
(8): 821-823.
August 2017
The renin-angiotensin system and prolylcarboxypeptidase.
Luft, F.C.
Journal of Molecular Medicine 95
(5): 461-463.
May 2017
Chronic thromboembolic pulmonary hypertension evolves diagnostically and therapeutically.
Luft, F.C.
Trends in Cardiovascular Medicine 27
(1): 38-40.
January 2017
Ghosts in the shell: identification of microglia in the human central nervous system by P2Y12 receptor.
Mildner, A.
Neural Regeneration Research 12
(4): 570-571.
April 2017
Activity-DEPendent Transposition.
Newman, A.G., Bessa, P., Tarabykin, V. and Singh, P.B.
EMBO Reports 18
(3): 346-348.
1 March 2017
Low-field cardiac magnetic resonance imaging: a compelling case for cardiac magnetic resonance's future response.
Niendorf, T., Schulz-Menger, J., Paul, K., Huelnhagen, T., Ferrari, V.A. and Hodge, R.
Circulation Cardiovascular Imaging 10
(6): e005446 (7).
13 June 2017
Contribution of blood vessels to retinal nerve fiber layer thickness in NMOSD.
Oertel, F.C., Zimmermann, H., Mikolajczak, J., Weinhold, M., Kadas, E.M., Oberwahrenbrock, T., Pache, F., Bellmann-Strobl, J., Ruprecht, K., Paul, F. and Brandt, A.U.
Neurology Neuroimmunology & Neuroinflammation 4
(3): e338.
May 2017
Metabolic control and oxidative stress in pathological cardiac remodelling.
Schiattarella, G.G. and Hill, J.A.
European Heart Journal 38
(18): 1399-1401.
7 May 2017
Is load-induced ventricular hypertrophy ever compensatory?
Schiattarella, G.G., Hill, T.M. and Hill, J.A.
Circulation 136
(14): 1273-1275.
3 October 2017
UroFors: Konstituierung eines Interessensverbundes fuer Naturwissenschaftler in der urologischen Forschung [UroFors: establishment of an interest group for natural scientists in urological research].
Stope, M.B., Dansranjavin, T., Erb, H., Erdmann, K., Fendler, A., Hoelters, S., Juengel, E., Nitschke, K., Salomo, K., Seidel, P., Skowron, M.A., Wach, S. and Becker, C.
Urologe 56
(4): 515-518.
April 2017
A finer print than TADs: PRC1-mediated domains.
Torlai Triglia, E., Rito, Tiago and Pombo, A.
Molecular Cell 65
(3): 373-375.
2 February 2017
Michael Potente: no time to waste.
Williams, R.
Circulation Research 121
(5): 490-491.
18 August 2017
Nanotubes, the fast track to treatment of Dent disease?
Willnow, T.E.
Kidney International 91
(4): 776-778.
April 2017
Noisy networks and autism.
Winterer, G.
Biological Psychiatry 82
(3): 152-154.
1 August 2017
Trained macrophages support hygiene hypothesis.
de Laval, B. and Sieweke, M.H.
Nature Immunology 18
(12): 1279-1280.
16 November 2017
Advanced assessment of aortic stenosis reflecting the complex interplay of valve, ventricle, vessel, and flow.
von Knobelsdorff-Brenkenhoff, F.
Circulation Cardiovascular Imaging 10
(6): e006594.
June 2017
Preprint
GAMtools: an automated pipeline for analysis of Genome Architecture Mapping data.
Beagrie, R.A. and Schueler, M.
bioRxiv
: 114710.
20 March 2017
Assessing the gene regulatory landscape in 1,188 human tumors.
Calabrese, C., Lehmann, K.V., Urban, L., Liu, F., Erkek, S., Fonseca, N., Kahles, A., Kilpinen-Barrett, L.H., Markowski, J., Waszak, S., Korbel, J., Zhang, Z., Brazma, A., Raetsch, G., Schwarz, R. and Stegle, O.
bioRxiv
: 225441.
29 November 2017
Visualization of class A GPCR oligomerization by image-based fluorescence fluctuation spectroscopy.
Isbilir, A., Moeller, J., Bock, A., Zabel, U., Annibale, P. and Lohse, M.J.
bioRxiv
: 240903.
29 December 2017
Massively parallel clonal analysis using CRISPR/Cas9 induced genetic scars.
Junker, J.P., Spanjaard, B., Peterson-Maduro, J., Alemany, A., Hu, B., Florescu, M. and van Oudenaarden, A.
bioRxiv
: 056499.
4 January 2017
No major flaws in "Identification of individuals by trait prediction using whole-genome sequencing data".
Lippert, C., Sabatini, R., Maher, M.C., Kang, E.Y., Lee, S., Arikan, O., Harley, A., Bernal, A., Garst, P., Lavrenko, V., Yocum, K., Wong, T.M., Zhu, M., Yang, W.Y.n, Chang, C., Hicks, B., Ramakrishnan, S., Tang, H., Xie, C., Brewerton, S., Turpaz, Y., Telenti, A., Roby, R.K., Och, F. and Venter, J.C.
bioRxiv
: 187542.
19 October 2017
Video
How are different transcripts in our genome translated into proteins?
Ohler, U.
[Video]
2017
Other
George Klein: 1925-2016.
Rajewsky, K.
National Academy of Sciences.
28 March 2017
This list was generated on Mon Dec 2 09:38:35 2024 UTC.