Items where Year is 2017

Article

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution.
Abbosh, C., Birkbak, N.J., Wilson, G.A., Jamal-Hanjani, M., Constantin, T., Salari, R., Quesne, J.L., Moore, D.A., Veeriah, S., Rosenthal, R., Marafioti, T., Kirkizlar, E., Watkins, T.B.K., McGranahan, N., Ward, S., Martinson, L., Riley, J., Fraioli, F., Bakir, M.A., Grönroos, E., Zambrana, F., Endozo, R., Bi, W.L., Fennessy, F.M., Sponer, N., Johnson, D., Laycock, J., Shafi, S., Czyzewska-Khan, J., Rowan, A., Chambers, T., Matthews, N., Turajlic, S., Hiley, C., Lee, S.M., Forster, M.D., Ahmad, T., Falzon, M., Borg, E., Lawrence, D., Hayward, M., Kolvekar, S., Panagiotopoulos, N., Janes, S.M., Thakrar, R., Ahmed, A., Blackhall, F., Summers, Y., Hafez, D., Naik, A., Ganguly, A., Kareht, S., Shah, R., Joseph, L., Quinn, A.M., Crosbie, P., Naidu, B., Middleton, G., Langman, G., Trotter, S., Nicolson, M., Remmen, H., Kerr, K., Chetty, M., Gomersall, L., Fennell, D.A., Nakas, A., Rathinam, S., Anand, G., Khan, S., Russell, P., Ezhil, V., Ismail, B., Irvin-Sellers, M., Prakash, V., Lester, J.F., Kornaszewska, M., Attanoos, R., Adams, H., Davies, H., Oukrif, D., Akarca, A.U., Hartley, J.A., Lowe, H.L., Lock, S., Iles, N., Bell, H., Ngai, Y., Elgar, G., Szallasi, Z., Schwarz, R.F., Herrero, J., Stewart, A., Quezada, S.A., Van Loo, P., Dive, C., Lin, C.J., Rabinowitz, M., Aerts, H.J.W.L., Hackshaw, A., Shaw, J.A., Zimmermann, B.G. and Swanton, C.
Nature 545 (7655): 446-451. 25 May 2017

Validity and reliability of total body volume and relative body fat mass from a 3-dimensional photonic body surface scanner.
Adler, C., Steinbrecher, A., Jaeschke, L., Mähler, A., Boschmann, M., Jeran, S. and Pischon, T.
PLoS ONE 12 (7): e0180201. 3 July 2017

Patched receptors sense, interpret and establish an epidermal Hedgehog signalling gradient.
Adolphe, C., Junker, J.P., Lyubimova, A., van Oudenaarden, A. and Wainwright, B.
Journal of Investigative Dermatology 137 (1): 179-186. January 2017

Genetic heterogeneity in Pakistani microcephaly families revisited.
Ahmad, I., Baig, S.M., Abdulkareem, A.R., Hussain, M.S., Sur, I., Toliat, M.R., Nürnberg, G., Dalibor, N., Moawia, A., Waseem, S.S., Asif, M., Nagra, H., Sher, M., Khan, M.M.A., Hassan, I., Rehman, S.U., Thiele, H., Altmüller, J., Noegel, A.A. and Nürnberg, P.
Clinical Genetics 92 (1): 62-68. July 2017

Toxoplasma co-infection prevents Th2 differentiation and leads to a helminth-specific Th1 response.
Ahmed, N., French, T., Rausch, S., Kühl, A., Hemminger, K., Dunay, I.R., Steinfelder, S. and Hartmann, S.
Frontiers in Cellular and Infection Microbiology 7 : 341. 25 July 2017

Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A., Xavier, A., Abu Lubad, M., Sigulla, J., Kessler, M., Hurwitz, R. and Meyer, T.F.
EBioMedicine 23 : 100-110. September 2017

Late diagnosis of a truncating WISP3 mutation entails a severe phenotype of progressive pseudorheumatoid dysplasia.
Alawbathani, S., Kawalia, A., Karakaya, M., Altmüller, J., Nürnberg, P. and Cirak, S.
Cold Spring Harbor Molecular Case Studies 4 (1): a002139. 19 December 2017

Viral to metazoan marine plankton nucleotide sequences from the Tara Oceans expedition.
Alberti, A., Poulain, J., Engelen, S., Labadie, K., Romac, S., Ferrera, I., Albini, G., Aury, J.M., Belser, C., Bertrand, A., Cruaud, C., Da Silva, C., Dossat, C., Gavory, F., Gas, S., Guy, J., Haquelle, M., Jacoby, E., Jaillon, O., Lemainque, A., Pelletier, E., Samson, G., Wessner, M., Acinas, S.G., Royo-Llonch, M., Cornejo-Castillo, F.M., Logares, R., Fernandez-Gomez, B., Bowler, C., Cochrane, G., Amid, C., Hoopen, P.T., De Vargas, C., Grimsley, N., Desgranges, E., Kandels-Lewis, S., Ogata, H., Poulton, N., Sieracki, M.E., Stepanauskas, R., Sullivan, M.B., Brum, J.R., Duhaime, M.B., Poulos, B.T., Hurwitz, B.L., Pesant, S., Karsenti, E. and Wincker, P.
Scientific Data 4 : 170093. 1 August 2017

Optical coherence tomography for the diagnosis and monitoring of idiopathic intracranial hypertension.
Albrecht, P., Blasberg, C., Ringelstein, M., Mueller, A.K., Finis, D., Guthoff, R., Kadas, E.M., Lagreze, W., Aktas, O., Hartung, H.P., Paul, F., Brandt, A.U. and Methner, A.
Journal of Neurology 264 (7): 1370-1380. July 2017

Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort.
Aleksandrova, K., Jenab, M., Leitzmann, M., Bueno-de-Mesquita, B., Kaaks, R., Trichopoulou, A., Bamia, C., Lagiou, P., Rinaldi, S., Freisling, H., Carayol, M., Pischon, T., Drogan, D., Weiderpass, E., Jakszyn, P., Overvad, K., Dahm, C.C., Tjønneland, A., Bouton-Ruault, M.C., Kühn, T., Peppa, E., Valanou, E., La Vecchia, C., Palli, D., Panico, S., Sacerdote, C., Agnoli, C., Tumino, R., May, A., van Vulpen, J., Benjaminsen Borch, K., Oluwafemi Oyeyemi, S., Quirós, J.R., Bonet, C., Sánchez, M.J., Dorronsoro, M., Navarro, C., Barricarte, A., van Guelpen, B., Wennberg, P., Key, T.J., Khaw, K.T., Wareham, N., Assi, N., Ward, H.A., Aune, D., Riboli, E. and Boeing, H.
International Journal of Epidemiology 46 (6): 1823-1835. 1 December 2017

Metabolic mediators of the association between adult weight gain and colorectal cancer: data from the european prospective investigation into cancer and nutrition (EPIC) cohort.
Aleksandrova, K., Schlesinger, S., Fedirko, V., Jenab, M., Bueno-de-Mesquita, B., Freisling, H., Romieu, I., Pischon, T., Kaaks, R., Gunter, M.J., Dahm, C.C., Overvad, K., Rostgaard-Hansen, A.L., Tjønneland, A., Trichopoulou, A., Bamia, C., Lagiou, P., Agnoli, C., Mattiello, A., Bradbury, K., Khaw, K.T., Riboli, E. and Boeing, H.
American Journal of Epidemiology 185 (9): 751-764. May 2017

Cell fixation and preservation for droplet-based single-cell transcriptomics.
Alles, J., Karaiskos, N., Praktiknjo, S.D., Grosswendt, S., Wahle, P., Ruffault, P.L., Ayoub, S., Schreyer, L., Boltengagen, A., Birchmeier, C., Zinzen, R., Kocks, C. and Rajewsky, N.
BMC Biology 15 (1): 44. 19 May 2017

Mutational profiling in the peripheral blood leukocytes of patients with systemic mast cell activation syndrome using next-generation sequencing.
Altmüller, J., Haenisch, B., Kawalia, A., Menzen, M., Nöthen, M.M., Fier, H. and Molderings, G.J.
Immunogenetics 69 (6): 359-369. June 2017

Satb2(Cre/+) mouse as a tool to investigate cell fate determination in the developing neocortex.
Ambrozkiewicz, M.C., Bessa, P., Salazar-Lázaro, A., Salina, V. and Tarabykin, V.
Journal of Neuroscience Methods 291 : 113-121. 1 November 2017

The immune system prevents recurrence of transplanted but not autochthonous antigenic tumors after oncogene inactivation therapy.
Anders, K., Kershaw, O., Larue, L., Gruber, A.D. and Blankenstein, T.
International Journal of Cancer 141 (12): 2551-2561. 15 December 2017

Aggregation of full length immunoglobulin light chains from AL amyloidosis patients is remodeled by epigallocatechin-3-gallate.
Andrich, K., Hegenbart, U., Kimmich, C., Kedia, N., Bergen, H.R., Schönland, S., Wanker, E.E. and Bieschke, J.
Journal of Biological Chemistry 292 (6): 2328-2344. 10 February 2017

Discovery of a novel series of tankyrase inhibitors by a hybridization approach.
Anumala, U.R., Waaler, J., Nkizinkiko, Y., Ignatev, A., Lazarow, K., Lindemann, P., Olsen, P.A., Murthy, S., Obaji, E., Majouga, A.G., Leonov, S., von Kries, J.P., Lehtiö, L., Krauss, S. and Nazaré, M.
Journal of Medicinal Chemistry 60 (24): 10013-10025. 28 December 2017

Touch receptor-derived sensory information alleviates acute pain signaling and fine-tunes nociceptive reflex coordination.
Arcourt, A., Gorham, L., Dhandapani, R., Prato, V., Taberner, F.J., Wende, H., Gangadharan, V., Birchmeier, C., Heppenstall, P.A. and Lechner, S.G.
Neuron 93 (1): 179-193. 4 January 2017

Human SLFN5 is a transcriptional co-repressor of STAT1-mediated interferon responses and promotes the malignant phenotype in glioblastoma.
Arslan, A.D., Sassano, A., Saleiro, D., Lisowski, P., Kosciuczuk, E.M., Fischietti, M., Eckerdt, F., Fish, E.N. and Platanias, L.C.
Oncogene 36 (43): 6006-6019. 26 October 2017

Disruption of the leptomeningeal blood barrier in neuromyelitis optica spectrum disorder.
Asgari, N., Flanagan, E.P., Fujihara, K., Kim, H.J., Skejoe, H.P., Wuerfel, J., Kuroda, H., Kim, S.H., Maillart, E., Marignier, R., Pittock, S.J., Paul, F. and Weinshenker, B.G.
Neurology Neuroimmunology & Neuroinflammation 4 (4): e343. July 2017

Insulin-like growth factor (IGF) binding protein-2, independently of IGF-1, induces GLUT-4 translocation and glucose uptake in 3T3-L1 adipocytes.
Assefa, B., Mahmoud, A.M., Pfeiffer, A.F.H., Birkenfeld, A.L., Spranger, J. and Arafat, A.M.
Oxidative Medicine and Cellular Longevity 2017 : 3035184. 20 December 2017

Collagen cell carriers seeded with human urothelial cells for urethral reconstructive surgery: first results in a xenograft minipig model.
Aufderklamm, S., Vaegler, M., Kelp, A., Maurer, S., Gustafsson, L., Mundhenk, J., Busch, S., Daum, L., Stenzl, A., Amend, B. and Sievert, K.D.
World Journal of Urology 35 (7): 1125-1132. July 2017

A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle.
Awazawa, M., Gabel, P., Tsaousidou, E., Nolte, H., Krüger, M., Schmitz, J., Ackermann, P.J., Brandt, C., Altmüller, J., Motameny, S., Wunderlich, F.T., Kornfeld, J.W., Blüher, M. and Brüning, J.C.
Nature Medicine 23 (12): 1466-1473. 1 December 2017

RNA-bioinformatics: tools, services and databases for the analysis of RNA-based regulation.
Backofen, R., Engelhardt, J., Erxleben, A., Fallmann, J., Grüning, B., Ohler, U., Rajewsky, N. and Stadler, P.F.
Journal of Biotechnology 261 : 76-84. 10 November 2017

Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis.
Baddack-Werncke, U., Busch-Dienstfertig, M., Gonzalez-Rodriguez, S., Maddila, S.C., Grobe, J., Lipp, M., Stein, C. and Mueller, G.
Journal of Neuroinflammation 14 (1): 30. 6 February 2017

Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium.
Balzus, B., Sahle, F.F., Hönzke, S., Gerecke, C., Schumacher, F., Hedtrich, S., Kleuser, B. and Bodmeier, R.
European Journal of Pharmaceutics and Biopharmaceutics 115 : 122-130. June 2017

Subsequent malignancies among long-term survivors of Hodgkin lymphoma and non-Hodgkin lymphoma: a pooled analysis of German cancer registry data (1990-2012).
Baras, N., Dahm, S., Haberland, J., Janz, M., Emrich, K., Kraywinkel, K. and Salama, A.
British Journal of Haematology 177 (2): 226-242. April 2017

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells.
Barbieri, M., Xie, S.Q., Torlai Triglia, E., Chiariello, A.M., Bianco, S., de Santiago, I., Branco, M.R., Rueda, D., Nicodemi, M. and Pombo, A.
Nature Structural & Molecular Biology 24 (6): 515-524. June 2017

Complex multi-enhancer contacts captured by genome architecture mapping.
Beagrie, R.A., Scialdone, A., Schueler, M., Kraemer, D.C.A., Chotalia, M., Xie, S.Q., Barbieri, M., de Santiago, I., Lavitas, L.M., Branco, M.R., Fraser, J., Dostie, J., Game, L., Dillon, N., Edwards, P.A.W., Nicodemi, M. and Pombo, A.
Nature 543 (7646): 519-524. 23 March 2017

Elastase-2, a tissue alternative pathway for angiotensin II generation, plays a role in circulatory sympathovagal balance in mice.
Becari, C., Durand, M.T., Guimaraes, A.O., Lataro, R.M., Prado, C.M., de Oliveira, M., Candido, S.C.O., Pais, P., Ribeiro, M.S., Bader, M., Pesquero, J.B., Salgado, M.C.O. and Salgado, H.C.
Frontiers in Physiology 8 : 170. 23 March 2017

Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naive Parkinson's disease patients.
Bedarf, J.R., Hildebrand, F., Coelho, L.P., Sunagawa, S., Bahram, M., Goeser, F., Bork, P. and Wuellner, U.
Genome Medicine 9 (1): 39. 28 April 2017

Mathematical modelling of promoter occupancies in MYC-dependent gene regulation.
Benary, U., Wolf, E. and Wolf, J.
Genomics and Computational Biology 3 (2): e54. 2017

Proarrhythmic remodelling of the right ventricle in a porcine model of repaired tetralogy of Fallot.
Benoist, D., Dubes, V., Roubertie, F., Gilbert, S.H., Charron, S., Constantin, M., Elbes, D., Vieillot, D., Quesson, B., Cochet, H., Haissaguerre, M., Rooryck, C., Bordachar, P., Thambo, J.B. and Bernus, O.
Heart 103 (5): 347-354. March 2017

Ligand-specific restriction of extracellular conformational dynamics constrains signaling of the M(2) muscarinic receptor.
Bermudez, M., Bock, A., Krebs, F., Holzgrabe, U., Mohr, K., Lohse, M.J. and Wolber, G.
ACS Chemical Biology 12 (7): 1743-1748. 21 July 2017

Genetic tracing of Ca(V)3.2 T-type calcium channel expression in the peripheral nervous system.
Bernal Sierra, Y.A., Haseleu, J., Kozlenkov, A., Bégay, V. and Lewin, G.R.
Frontiers in Molecular Neuroscience 10 (70): 70. 15 March 2017

Inflammation-induced brain endothelial activation leads to uptake of electrostatically stabilized iron oxide nanoparticles via sulfated glycosaminoglycans.
Berndt, D., Millward, J.M., Schnorr, J., Taupitz, M., Stangl, V., Paul, F., Wagner, S., Wuerfel, J.T., Sack, I., Ludwig, A. and Infante-Duarte, C.
Nanomedicine: Nanotechnology, Biology and Medicine 13 (4): 1411-1421. May 2017

Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism.
Biagosch, C., Ediga, R.D., Hensler, S.V., Faerberboeck, M., Kuehn, R., Wurst, W., Meitinger, T., Kölker, S., Sauer, S. and Prokisch, H.
Biochimica et Biophysica Acta - Molecular Basis of Disease 1863 (9): 2220-2228. September 2017

On mass ambiguities in high-resolution shotgun lipidomics.
Bielow, C., Mastrobuoni, G., Orioli, M. and Kempa, S.
Analytical Chemistry 89 (5): 2986-2994. 7 March 2017

Identification and functional characterization of hypoxia-induced endoplasmic reticulum stress regulating lncRNA (HypERlnc) in pericytes.
Bischoff, F.C., Werner, A., John, D., Boeckel, J.-N., Melissari, M.-T., Grote, P., Glaser, S.F., Demolli, S., Uchida, S., Michalik, K.M., Meder, B., Katus, H.A., Haas, J., Chen, W., Pullamsetti, S.S., Seeger, W., Zeiher, A.M., Dimmeler, S. and Zehendner, C.M.
Circulation Research 121 (4): 368-375. 4 August 2017

Calcineurin inhibitor cyclosporine a activates renal Na-K-Cl cotransporters via local and systemic mechanisms.
Blankenstein, K.I., Borschewski, A., Labes, R., Paliege, A., Boldt, C., McCormick, J.A., Ellison, D.H., Bader, M., Bachmann, S. and Mutig, K.
American Journal of Physiology Renal Physiology 312 (3): F489-F501. 2 March 2017

Influence of spatial resolution and contrast agent dosage on myocardial T1 relaxation times.
Blaszczyk, E., Töpper, A., Schmacht, L., Wanke, F., Greiser, A., Schulz-Menger, J. and von Knobelsdorff-Brenkenhoff, F.
Magnetic Resonance Materials in Physics Biology and Medicine 30 (1): 85-91. February 2017

A dual role of Caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development.
Boege, Y., Malehmir, M., Healy, M.E., Bettermann, K., Lorentzen, A., Vucur, M., Ahuja, A.K., Böhm, F., Mertens, J.C., Shimizu, Y., Frick, L., Remouchamps, C., Mutreja, K., Kähne, T., Sundaravinayagam, D., Wolf, M.J., Rehrauer, H., Koppe, C., Speicher, T., Padrissa-Altés, S., Maire, R., Schattenberg, J.M., Jeong, J.S., Liu, Lei, Zwirner, S., Boger, R., Hüser, N., Davis, R.J., Müllhaupt, B., Moch, H., Schulze-Bergkamen, H., Clavien, P.A., Werner, S., Borsig, L., Luther, S.A., Jost, P.J., Weinlich, R., Unger, K., Behrens, A., Hillert, L., Dillon, C., Di Virgilio, M., Wallach, D., Dejardin, E., Zender, L., Naumann, M., Walczak, H., Green, D.R., Lopes, M., Lavrik, I., Luedde, T., Heikenwalder, M. and Weber, A.
Cancer Cell 32 (3): 342-359. 11 September 2017

Polysialic acid regulates sympathetic outflow by facilitating information transfer within the nucleus of the solitary tract.
Bokiniec, P., Shahbazian, S., McDougall, S.J., Berning, B.A., Cheng, D., Llewellyn-Smith, I.J., Burke, P.G.R., McMullan, S., Muehlenhoff, M., Hildebrandt, H., Braet, F., Connor, M., Packer, N.H. and Goodchild, A.K.
Journal of Neuroscience 37 (27): 6558-6574. 5 July 2017

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders.
Borisow, N., Kleiter, I., Gahlen, A., Fischer, K., Wernecke, K.D., Pache, F., Ruprecht, K., Havla, J., Krumbholz, M., Kümpfel, T., Aktas, O., Ringelstein, M., Geis, C., Kleinschnitz, C., Berthele, A., Hemmer, B., Angstwurm, K., Weissert, R., Stellmann, J.P., Schuster, S., Stangel, M., Lauda, F., Tumani, H., Mayer, C., Zeltner, L., Ziemann, U., Linker, R.A., Schwab, M., Marziniak, M., Then Bergh, F., Hofstadt-van Oy, U., Neuhaus, O., Winkelmann, A., Marouf, W., Rückriem, L., Faiss, J., Wildemann, B., Paul, F., Jarius, S., Trebst, C. and Hellwig, K.
Multiple Sclerosis Journal 23 (8): 1092-1103. July 2017

Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study.
Bove, R., Elsone, L., Alvarez, E., Borisow, N., Cortez, M.M., Mateen, F.J., Mealy, M.A., Mutch, K., Tobyne, S., Ruprecht, K., Buckle, G., Levy, M., Wingerchuk, D.M., Paul, F., Cross, A.H., Weinshenker, B., Jacob, A., Klawiter, E.C. and Chitnis, T.
Neurology Neuroimmunology & Neuroinflammation 4 (3): e339. May 2017

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Bowl, M.R., Simon, M.M., Ingham, N.J., Greenaway, S., Santos, L., Cater, H., Taylor, S., Mason, J., Kurbatova, N., Pearson, S., Bower, L.R., Clary, D.A., Meziane, H., Reilly, P., Minowa, O., Kelsey, L., Tocchini-Valentini, G.P., Gao, X., Bradley, A., Skarnes, W.C., Moore, M., Beaudet, A.L., Justice, M.J., Seavitt, J., Dickinson, M.E., Wurst, W., Hrabe de Angelis, M., Herault, Y., Wakana, S., Nutter, L.M.J., Flenniken, A.M., McKerlie, C., Murray, S.A., Svenson, K.L., Braun, R.E., West, D.B., Lloyd, K.C.K., Adams, D.J., White, J., Karp, N., Flicek, P., Smedley, D., Meehan, T.F., Parkinson, H.E., Teboul, L.M., Wells, S., Steel, K.P., Mallon, A.M. and Brown, S.D.M.
Nature Communications 8 (1): 886. 12 October 2017

Lipidome determinants of maximal lifespan in mammals.
Bozek, K., Khrameeva, E.E., Reznick, J., Omerbašić, D., Bennett, N.C., Lewin, G.R., Azpurua, J., Gorbunova, V., Seluanov, A., Regnard, P., Wanert, F., Marchal, J., Pifferi, F., Aujard, F., Liu, Z., Shi, P., Pääbo, S., Schroeder, F., Willmitzer, L., Giavalisco, P. and Khaitovich, P.
Scientific Reports 7 : 5. 31 January 2017

Heterozygous HNRNPU variants cause early onset epilepsy and severe intellectual disability.
Bramswig, N.C., Lüdecke, H.J., Hamdan, F.F., Altmüller, J., Beleggia, F., Elcioglu, N.H., Freyer, C., Gerkes, E.H., Demirkol, Y.K., Knupp, K.G., Kuechler, A., Li, Y., Lowenstein, D.H., Michaud, J.L., Park, K., Stegmann, A.P.A., Veenstra-Knol, H.E., Wieland, T., Wollnik, B., Engels, H., Strom, T.M., Kleefstra, T. and Wieczorek, D.
Human Genetics 136 (7): 821-834. July 2017

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.
Brocks, D., Schmidt, C.R., Daskalakis, M., Jang, H.S., Shah, N.M., Li, D., Li, J., Zhang, B., Hou, Y., Laudato, S., Lipka, D.B., Schott, J., Bierhoff, H., Assenov, Y., Helf, M., Ressnerova, A., Islam, M.S., Lindroth, A.M., Haas, S., Essers, M., Imbusch, C.D., Brors, B., Oehme, I., Witt, O., Lübbert, M., Mallm, J.P., Rippe, K., Will, R., Weichenhan, D., Stoecklin, G., Gerhäuser, C., Oakes, C.C., Wang, T. and Plass, C.
Nature Genetics 49 (7): 1052-1060. July 2017

Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities.
Bunina, D., Štefl, M., Huber, F., Khmelinskii, A., Meurer, M., Barry, J.D., Kats, I., Kirrmaier, D., Huber, W. and Knop, M.
Nucleic Acids Research 45 (19): 11144-11158. 2 November 2017

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Buonocore, F., Kuehnen, P., Suntharalingham, J.P., Del Valle, I., Digweed, M., Stachelscheid, H., Khajavi, N., Didi, M., Brady, A.F., Blankenstein, O., Procter, A.M., Dimitri, P., Wales, J.K.H., Ghirri, P., Knoebl, D., Strahm, B., Erlacher, M., Wlodarski, M.W., Chen, W., Kokai, G.K., Anderson, G., Morrogh, D., Moulding, D.A., McKee, S. A., Niemeyer, C.M., Grueters, A. and Achermann, J.C.
Journal of Clinical Investigation 127 (5): 1700-1713. 1 May 2017

Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies.
Burghi, V., Fernández, N.C., Gándola, Y.B., Piazza, V.G., Quiroga, D.T., Guilhen Mario, E., Felix Braga, J., Bader, M., Santos, R.A.S., Dominici, F.P. and Munoz, M.C.
PLoS ONE 12 (8): e0183278. 16 August 2017

Role of IL-17-producing lymphocytes in severity of multiple sclerosis upon natalizumab treatment.
Bühler, U., Fleischer, V., Luessi, F., Rezk, A., Belikan, P., Graetz, C., Gollan, R., Wolf, C., Lutz, J., Bar-Or, A., Siffrin, V. and Zipp, F.
Multiple Sclerosis Journal 23 (4): 567-576. 1 April 2017

Mapping interpuff interval distribution to the properties of inositol trisphosphate receptors.
Cao, P., Falcke, M. and Sneyd, J.
Biophysical Journal 112 (10): 2138-2146. 23 May 2017

Experimental validation of a preclinical SPECT/MR insert.
Carminati, M., Occhipinti, M., Baratelli, F. M., Montagnani, G. L., Nagy, K., Nyitrai, Z., Nagy, A., Czeller, M., Kühne, A., Niendorf, T., Mathe, D., Belloli, S., Valtorta, S., Moresco, R. M., Falini, A., Iadanza, A., Ottobrini, L. and Fiorini, C.
IEEE Nuclear Science Symposium and Medical Imaging Conference : 18264750. 2017

Identification of a novel benzimidazole pyrazolone scaffold that inhibits KDM4 lysine demethylases and reduces proliferation of prostate cancer cells.
Carter, D.M., Specker, E., Przygodda, J., Neuenschwander, M., von Kries, J.P., Heinemann, U., Nazaré, M. and Gohlke, U.
SLAS Discovery 22 (7): 801-812. 1 August 2017

Serotonin regulates prostate growth through androgen receptor modulation.
Carvalho-Dias, E., Miranda, A., Martinho, O., Mota, P., Costa, A., Nogueira-Silva, C., Moura, R.S., Alenina, N., Bader, M., Autorino, R., Lima, E. and Correia-Pinto, J.
Scientific Reports 7 (1): 15428. 13 November 2017

Impaired vitreous composition and retinal pigment epithelium function in the FoxG1::LRP2 myopic mice.
Cases, O., Obry, A., Ben-Yacoub, S., Augustin, S., Joseph, A., Toutirais, G., Simonutti, M., Christ, A., Cosette, P. and Kozyraki, R.
Biochimica et Biophysica Acta - Molecular Cell Research 1863 (6): 1242-1254. June 2017

Dynamo Catalogue: geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms.
Castaño-Díez, D., Kudryashev, M. and Stahlberg, H.
Journal of Structural Biology 197 (2): 135-144. February 2017

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.
Cerdá-Esteban, N., Naumann, H., Ruzittu, S., Mah, N., Pongrac, I.M., Cozzitorto, C., Hommel, A., Andrade-Navarro, M.A., Bonifacio, E. and Spagnoli, F.M.
Nature Communications 8 : 14127. 13 February 2017

OGEE v2: an update of the online gene essentiality database with special focus on differentially essential genes in human cancer cell lines.
Chen, W.H., Lu, G., Chen, X., Zhao, X.M. and Bork, P.
Nucleic Acids Research 45 (D1): D940-D944. 4 January 2017

Human TCR-MHC coevolution after divergence from mice includes increased nontemplate-encoded CDR3 diversity.
Chen, X., Poncette, L. and Blankenstein, T.
Journal of Experimental Medicine 214 (11): 3417-3433. 6 November 2017

Cellular and molecular identity of tumor-associated macrophages in glioblastoma.
Chen, Z., Feng, X., Herting, C.J., Alvarez Garcia, V., Nie, K., Pong, W.W., Rasmussen, R., Dwivedi, B., Seby, S., Wolf, S.A., Gutmann, D.H. and Hambardzumyan, D.
Cancer Research 77 (9): 2266-2278. 1 May 2017

Structural characterization and ligand/inhibitor identification provide functional insights into the mycobacterium tuberculosis cytochrome P450 CYP126A1.
Chenge, J.T., Duyet, L.V., Swami, S., McLean, K.J., Kavanagh, M.E., Coyne, A.G., Rigby, S.E.J., Cheesman, M.R., Girvan, H.M., Levy, C.W., Rupp, B., von Kries, J.P., Abell, C., Leys, D. and Munro, A.W.
Journal of Biological Chemistry 292 (4): 1310-1329. 27 January 2017

Quantitative profiling of hydroxy lipid metabolites in mouse organs reveals distinct lipidomic profiles and modifications due to elevated n-3 fatty acid levels.
Chiu, C.Y., Smyl, C., Dogan, I., Rothe, M. and Weylandt, K.H.
Biology 6 (1): E9. 4 February 2017

Endothelial NF-κB blockade abrogates ANCA-induced GN.
Choi, M., Schreiber, A., Eulenberg-Gustavus, C., Scheidereit, C., Kamps, J. and Kettritz, R.
Journal of the American Society of Nephrology 28 (11): 3191-3204. November 2017

CRISPR/Cas9-mediated in vitro mutagenesis in GC-like B cells.
Chu, V.T., Graf, R. and Rajewsky, K.
Methods in Molecular Biology 1623 : 135-145. 2017

Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods.
Churko, J.M., Lee, J., Ameen, M., Gu, M., Venkatasubramanian, M., Diecke, S., Sallam, K., Im, H., Wang, G., Gold, J.D., Salomonis, N., Snyder, M.P. and Wu, J.C.
Nature Biomedical Engineering 1 (10): 826-837. October 2017

C/EBP-induced transdifferentiation reveals granulocyte-macrophage precursor-like plasticity of B cells.
Cirovic, B., Schönheit, J., Kowenz-Leutz, E., Ivanovska, J., Klement, C., Pronina, N., Bégay, V. and Leutz, A.
Stem Cell Reports 14 (8): 346-359. 14 February 2017

Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat.
Coan, P.M., Hummel, O., Diaz, A.I.G., Barrier, M., Alfazema, N., Norsworthy, P.J., Pravenec, M., Petretto, E., Hübner, N. and Aitman, T.J.
Disease Models & Mechanisms 10 (3): 297-306. 1 March 2017

Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Consentius, P., Gohlke, U., Loll, B., Alings, C., Heinemann, U., Wahl, M.C. and Risse, T.
Physical Chemistry Chemical Physics 19 (31): 20723-20734. 9 August 2017

Internal dynamics of the 3-pyrroline-N-oxide ring in spin-labeled proteins.
Consentius, P., Loll, B., Gohlke, U., Alings, C., Müller, C., Müller, R., Teutloff, C., Heinemann, U., Kaupp, M., Wahl, M.C. and Risse, T.
Journal of Physical Chemistry Letters 8 (6): 1113-1117. 16 March 2017

Prevalence of metabolic syndrome in female and male patients at risk of psychosis.
Cordes, J., Bechdolf, A., Engelke, C., Kahl, K.G., Balijepalli, C., Loesch, C., Klosterkoetter, J., Wagner, M., Maier, W., Heinz, A., de Millas, W., Gaebel, W., Winterer, G., Janssen, B., Schmidt-Kraepelin, C., Schneider, F., Lambert, M., Juckel, G., Wobrock, T., Riedel, M. and Moebus, S.
Schizophrenia Research 181 : 38-42. March 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (first edition).
Cossarizza, A., Chang, H.D., Radbruch, A., Akdis, M., Andrä, I., Annunziato, F., Bacher, P., Barnaba, V., Battistini, L., Bauer, W.M., Baumgart, S., Becher, B., Beisker, W., Berek, C., Blanco, A., Borsellino, G., Boulais, P.E., Brinkman, R.R., Büscher, M., Busch, D.H., Bushnell, T.P., Cao, X., Cavani, A., Chattopadhyay, P.K., Cheng, Q., Chow, S., Clerici, M., Cooke, A., Cosma, A., Cosmi, L., Cumano, A., Dang, V.D., Davies, D., De Biasi, S., Del Zotto, G., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Diefenbach, A., Di Santo, J., Dieli, F., Dolf, A., Donnenberg, V.S., Dörner, T., Ehrhardt, G.R.A., Endl, E., Engel, P., Engelhardt, B., Esser, C., Everts, B., Dreher, A., Falk, C.S., Fehniger, T.A., Filby, A., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G.A., Frenette, P.S., Galbraith, D., Garbi, N., García-Godoy, M.D., Geginat, J., Ghoreschi, K., Gibellini, L., Goettlinger, C., Goodyear, C.S., Gori, A., Grogan, J., Gross, M., Grützkau, A., Grummitt, D., Hahn, J., Hammer, Q., Hauser, A.E., Haviland, D.L., Hedley, D., Herrera, G., Herrmann, M., Hiepe, F., Holland, T., Hombrink, P., Houston, J.P., Hoyer, B.F., Huang, B., Hunter, C.A., Iannone, A., Jäck, H.M., Jávega, B., Jonjic, S., Juelke, K., Jung, S., Kaiser, T., Kalina, T., Keller, B., Khan, S., Kienhöfer, D., Kroneis, T., Kunkel, D., Kurts, C., Kvistborg, P., Lannigan, J., Lantz, O., Larbi, A., LeibundGut-Landmann, S., Leipold, M.D., Levings, M.K., Litwin, V., Liu, Y., Lohoff, M., Lombardi, G., Lopez, L., Lovett-Racke, A., Lubberts, E., Ludewig, B., Lugli, E., Maecker, H.T., Martrus, G., Matarese, G., Maueröder, C., McGrath, M., McInnes, I., Mei, H.E., Melchers, F., Melzer, S., Mielenz, D., Mills, K., Mirrer, D., Mjösberg, J., Moore, J., Moran, B., Moretta, A., Moretta, L., Mosmann, T.R., Müller, S., Müller, W., Münz, C., Multhoff, G., Munoz, L.E., Murphy, K.M., Nakayama, T., Nasi, M., Neudörfl, C., Nolan, J., Nourshargh, S., O'Connor, J.E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Peterson, P., Peth, C., Petriz, J., Philips, D., Pickl, W., Piconese, S., Pinti, M., Pockley, A.G., Podolska, M.J., Pucillo, C., Quataert, S.A., Radstake, T.R.D.J., Rajwa, B., Rebhahn, J.A., Recktenwald, D., Remmerswaal, E.B.M., Rezvani, K., Rico, L.G., Robinson, J.P., Romagnani, C., Rubartelli, A., Ruckert, B., Ruland, J., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sawitzki, B., Scheffold, A., Schiemann, M., Schildberg, F., Schimisky, E., Schmid, S.A., Schmitt, S., Schober, K., Schüler, T., Schulz, A.R., Schumacher, T., Scotta, C., Shankey, T.V., Shemer, A., Simon, A.K., Spidlen, J., Stall, A.M., Stark, R., Stehle, C., Stein, M., Steinmetz, T., Stockinger, H., Takahama, Y., Tarnok, A., Tian, Z.G., Toldi, G., Tornack, J., Traggiai, E., Trotter, J., Ulrich, H., van der Braber, M., van Lier, R.A.W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H.D., von Volkmann, K., Waisman, A., Walker, R., Ward, M.D., Warnatz, K., Warth, S., Watson, J.V., Watzl, C., Wegener, L., Wiedemann, A., Wienands, J., Willimsky, G., Wing, J., Wurst, P., Yu, L., Yue, A., Zhang, Q., Zhao, Y., Ziegler, S. and Zimmermann, J.
European Journal of Immunology 47 (10): 1584-1797. 11 October 2017

Subspecies in the global human gut microbiome.
Costea, P.I., Coelho, L.P., Sunagawa, S., Munch, R., Huerta-Cepas, J., Forslund, K., Hildebrand, F., Kushugulova, A., Zeller, G. and Bork, P.
Molecular Systems Biology 13 (12): 960. 14 December 2017

MetaSNV: a tool for metagenomic strain level analysis.
Costea, P.I., Munch, R., Coelho, L.P., Paoli, L., Sunagawa, S. and Bork, P.
PLoS ONE 12 (7): e0182392. 28 July 2017

Towards standards for human fecal sample processing in metagenomic studies.
Costea, P.I., Zeller, G., Sunagawa, S., Pelletier, E., Alberti, A., Levenez, F., Tramontano, M., Driessen, M., Hercog, R., Jung, F.E., Kultima, J.R., Hayward, M.R., Coelho, L.P., Allen-Vercoe, E., Bertrand, L., Blaut, M., Brown, J.R.M., Carton, T., Cools-Portier, S., Daigneault, M., Derrien, M., Druesne, A., de Vos, W.M., Finlay, B.B., Flint, H.J., Guarner, F., Hattori, M., Heilig, H., Luna, R.A., van Hylckama Vlieg, J., Junick, J., Klymiuk, I., Langella, P., Le Chatelier, Z., Mai, V., Manichanh, C., Martin, J.C., Mery, C., Morita, H., O'Toole, P.W., Orvain, C., Patil, K.R., Penders, J., Persson, S., Pons, N., Popova, M., Salonen, A., Saulnier, D., Scott, K.P., Singh, B., Slezak, K., Veiga, P., Versalovic, J., Zhao, L., Zoetendal, E.G., Ehrlich, S.D., Dore, J. and Bork, P.
Nature Biotechnology 35 (11): 1069-1076. November 2017

Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.
Cui, H., Bansal, V., Grunert, M., Malecova, B., Dall Agnese, A., Latella, L., Gatto, S., Ryan, T., Schulz, K., Chen, W., Dorn, C., Puri, P.L. and Sperling, S.R.
PLoS ONE 12 (6): e0179464. 13 June 2017

Control of gene editing by manipulation of DNA repair mechanisms.
Danner, E., Bashir, S., Yumlu, S., Wurst, W., Wefers, B. and Kühn, R.
Mammalian Genome 28 (7-8): 262-274. August 2017

Improved cardiovascular autonomic modulation in transgenic rats expressing an Ang-(1-7)-producing fusion protein.
Dartora, D.R., Irigoyen, M.C., Casali, K.R., Moraes-Silva, I.C., Bertagnolli, M., Bader, M. and Santos, R.
Canadian Journal of Physiology and Pharmacology 95 (9): 993-998. September 2017

Channeling of branched flow in weakly scattering anisotropic media.
Degueldre, H., Metzger, J.J., Schultheis, E. and Fleischmann, R.
Physical Review Letters 118 (2): 024301. 13 January 2017

The MYCmRNA3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.
Dejure, F.R., Royla, N., Herold, S., Kalb, J., Walz, S., Ade, C.P., Mastrobuoni, G., Vanselow, J.T., Schlosser, A., Wolf, E., Kempa, S. and Eilers, M.
EMBO Journal 36 (13): 1854-1868. 3 July 2017

The 4D nucleome project.
Dekker, J., Belmont, A.S., Guttman, M., Leshyk, V.O., Lis, J.T., Lomvardas, S., Mirny, L.A., O'Shea, C.C., Park, P.J., Ren, B., Politz, J.C.R., Shendure, J. and Zhong, S.
Nature 549 (7671): 219-226. 14 September 2017

Copy number increases of transposable elements and protein-coding genes in an invasive fish of hybrid origin.
Dennenmoser, S., Sedlazeck, F.J., Iwaszkiewicz, E., Li, X.Y., Altmüller, J. and Nolte, A.W.
Molecular Ecology 26 (18): 4712-4724. 26 September 2017

Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress.
Devos, S., Van Putte, W., Vitse, J., Van Driessche, G., Stremersch, S., Van Den Broek, W., Raemdonck, K., Braeckmans, K., Stahlberg, H., Kudryashev, M., Savvides, S.N. and Devreese, B.
Environmental Microbiology 19 (10): 3930-3937. October 2017

Hypoxia-inducible factor-1α inhibition modulates airway hyperresponsiveness and nitric oxide levels in a BALB/c mouse model of asthma.
Dewitz, C., McEachern, E., Shin, S., Akong, K., Nagle, D.G., Broide, D.H., Akuthota, P. and Crotty Alexander, L.E.
Clinical Immunology 176 : 94-99. March 2017

Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain.
DiCara, D.M., Chirgadze, D.Y., Pope, A.R., Karatt-Vellatt, A., Winter, A., Slavny, P., van den Heuvel, J., Parthiban, K., Holland, J., Packman, L.C., Mavria, G., Hoffmann, J., Birchmeier, W., Gherardi, E. and McCafferty, J.
Scientific Reports 7 (1): 9000. 21 August 2017

Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis.
Dianzani, C., Bellavista, E., Liepe, J., Verderio, Cl., Martucci, M., Santoro, A., Chiocchetti, A., Luca Gigliotti, C., Boggio, E., Ferrara, B., Riganti, L., Keller, C., Janek, K., Niewienda, A., Fenoglio, C., Sorosina, M., Cantello, R., Kloetzel, P.M., Stumpf, M.P.H., Paul, F., Ruprecht, K., Galimberti, D., Martinelli Boneschi, F., Comi, C., Dianzani, U. and Mishto, M.
Scientific Reports 7 : 43718. 9 March 2017

Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.
Dimitrakopoulou, V.I., Tsilidis, K.K., Haycock, P.C., Dimou, N.L., Al-Dabhani, K., Martin, R.M., Lewis, S.J., Gunter, M.J., Mondul, A., Shui, I.M., Theodoratou, E., Nimptsch, K., Lindstroem, S., Albanes, D., Kuehn, T., Key, T.J., Travis, R.C., Vimaleswaran, K.S., Kraft, P., Pierce, B.L. and Schildkraut, J.M.
BMJ 359 : j4761. 31 October 2017

Claudin peptidomimetics modulate tissue barriers for enhanced drug delivery.
Dithmer, S., Staat, C., Müller, C., Ku, M.C., Pohlmann, A., Niendorf, T., Gehne, N., Fallier-Becker, P., Kittel, Á., Walter, F.R., Veszelka, S., Deli, M.A., Blasig, R., Haseloff, R.F., Blasig, I.E. and Winkler, L.
Annals of the New York Academy of Sciences 1397 (1): 169-184. June 2017

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J., Neuenschwander, M., Yu, Y., Däbritz, J.H.M., Neuendorff, N.R., Schleich, K., Bittner, A., Milanovic, M., Beuster, G., Radetzki, S., Specker, E., Reimann, M., Rosenbauer, F., Mathas, S., Lohneis, P., Hummel, M., Dörken, B., von Kries, J.P., Lee, S. and Schmitt, C.A.
Blood 129 (1): 71-81. 5 January 2017

Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.
Duchene, J., Novitzky-Basso, I., Thiriot, A., Casanova-Acebes, M., Bianchini, M., Etheridge, S.L., Hub, E., Nitz, K., Artinger, K., Eller, K., Caamano, J., Ruelicke, T., Moss, P., Megens, R.T.A., von Andrian, U.H., Hidalgo, A., Weber, C. and Rot, A.
Nature Immunology 18 (7): 753-761. July 2017

17β-estradiol-induced interaction of estrogen receptor α and human atrial essential myosin light chain modulates cardiac contractile function.
Duft, K., Schanz, M., Pham, H., Abdelwahab, A., Schriever, C., Kararigas, G., Dworatzek, E., Davidson, M.M., Regitz-Zagrosek, V., Morano, I. and Mahmoodzadeh, S.
Basic Research in Cardiology 112 (1): 1. January 2017

Brain iron accumulation in Wilson disease: a post-mortem 7 Tesla MRI - histopathological study.
Dusek, P., Bahn, E., Litwin, T., Jabłonka-Salach, K., Łuciuk, A., Huelnhagen, T., Madai, V.I., Dieringer, M.A., Bulska, E., Knauth, M., Niendorf, T., Sobesky, J., Paul, F., Schneider, S.A., Czlonkowska, A., Brück, W., Wegner, C. and Wuerfel, J.
Neuropathology and Applied Neurobiology 43 (6): 514-532. October 2017

Cell dynamics underlying oriented growth of the Drosophila wing imaginal disc.
Dye, N.A., Popović, M., Spannl, S., Etournay, R., Kainmüller, D., Ghosh, S., Myers, E.W., Jülicher, F. and Eaton, S.
Development 144 (23): 4406-4421. 1 December 2017

Pathogen-reactive T helper cell analysis in the pig.
Ebner, F., Schwiertz, P., Steinfelder, S., Pieper, R., Zentek, J., Schütze, N., Baums, C.G., Alber, G., Geldhof, P. and Hartmann, S.
Frontiers in Immunology 8 : 565. 17 May 2017

LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.
Ediger, B.N., Lim, H.W., Juliana, C., Groff, D.N., Williams, L.T., Dominguez, G., Liu, J.H., Taylor, B.L., Walp, E.R., Kameswaran, V., Yang, J., Liu, C., Hunter, C.S., Kaestner, K.H., Naji, A., Li, C., Sander, M., Stein, R., Sussel, L., Won, K.J., May, C.L. and Stoffers, D.A.
Journal of Clinical Investigation 127 (1): 215-229. 3 January 2017

Specific uptake mechanisms of well-tolerated thermoresponsive polyglycerol-based nanogels in antigen-presenting cells of the skin.
Edlich, Alexander, Gerecke, C., Giulbudagian, M., Neumann, F., Hedtrich, S., Schäfer-Korting, M., Ma, N., Calderon, M. and Kleuser, B.
European Journal of Pharmaceutics and Biopharmaceutics 116 : 155-163. July 2017

Drug resistance mechanisms in colorectal cancer dissected with cell type-specific dynamic logic models.
Eduati, F., Doldan-Martelli, V., Klinger, B., Cokelaer, T., Sieber, A., Kogera, F., Dorel, M., Garnett, M.J., Blüthgen, N. and Saez-Rodriguez, J.
Cancer Research 77 (12): 3364-3375. 15 June 2017

De novo mutations in SLC25A24 cause a craniosynostosis syndrome with hypertrichosis, progeroid appearance, and mitochondrial dysfunction.
Ehmke, N., Graul-Neumann, L., Smorag, L., Koenig, R., Segebrecht, L., Magoulas, P., Scaglia, F., Kilic, E., Hennig, A.F., Adolphs, N., Saha, N., Fauler, B., Kalscheuer, V.M., Hennig, F., Altmüller, J., Netzer, C., Thiele, H., Nürnberg, P., Yigit, G., Jäger, M., Hecht, J., Krüger, U., Mielke, T., Krawitz, P.M., Horn, D., Schuelke, M., Mundlos, S., Bacino, C.A., Bonnen, P.E., Wollnik, B., Fischer-Zirnsak, B. and Kornak, U.
American Journal of Human Genetics 101 (5): 833-843. 2 November 2017

Increased placental sFlt-1 but unchanged PlGF expression in late-onset preeclampsia.
Ehrlich, L., Hoeller, A., Golic, M., Herse, F., Perschel, F.H., Henrich, W., Dechend, R., Huppertz, B. and Verlohren, S.
Hypertension in Pregnancy 36 (2): 175-185. May 2017

Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
Eichenauer, D.A., Plütschow, A., Kreissl, S., Sökler, M., Hellmuth, J.C., Meissner, J., Mathas, S., Topp, M.S., Behringer, K., Klapper, W., Kuhnert, G., Dietlein, M., Kobe, C., Fuchs, M., Diehl, V., Engert, A. and Borchmann, P.
Lancet Oncology 18 (12): 1680-1687. December 2017

In colon epithelia, Clostridium perfringens enterotoxin causes focal leaks by targeting claudins which are apically accessible due to tight junction derangement.
Eichner, M., Augustin, C., Fromm, A., Piontek, A., Walther, W., Buecker, R., Fromm, M., Krause, G., Schulzke, J.D., Guenzel, D. and Piontek, J.
Journal of Infectious Diseases 217 (1): 147-157. 27 December 2017

The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
El-Athman, R., Genov, N.N., Mazuch, J., Zhang, K., Yu, Y., Fuhr, L., Abreu, M., Li, Y., Wallach, T., Kramer, A., Schmitt, C.A. and Relógio, A.
PLoS Biology 15 (12): e2002940. 7 December 2017

Sugar metabolism of the first thermophilic planctomycete thermogutta terrifontis: comparative genomic and transcriptomic approaches.
Elcheninov, A.G., Menzel, P., Gudbergsdottir, S.R., Slesarev, A.I., Kadnikov, V.V., Krogh, A., Bonch-Osmolovskaya, E.A., Peng, X. and Kublanov, I.V.
Frontiers in Microbiology 8 : 2140. 2 November 2017

A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Elling, U., Wimmer, R.A., Leibbrandt, A., Burkard, T., Michlits, G., Leopoldi, A., Micheler, T., Abdeen, D., Zhuk, S., Aspalter, I.M., Handl, C., Liebergesell, J., Hubmann, M., Husa, A.M., Kinzer, M., Schuller, N., Wetzel, E., van de Loo, N., Martinez, J.A.Z., Estoppey, D., Riedl, R., Yang, F., Fu, B., Dechat, T., Ivics, Z., Agu, C.A., Bell, O., Blaas, D., Gerhardt, H., Hoepfner, D., Stark, A. and Penninger, J.M.
Nature 550 (7674): 114-118. 5 October 2017

Systemic and tissue-specific effects of aliskiren on the RAAS and carbohydrate/lipid metabolism in obese patients with hypertension.
Engeli, S., May, M., Nussberger, J., Danser, A.H.J., Dole, W.P., Prescott, M.F., Dahlke, M., Stitah, S., Pal, P., Boschmann, M. and Jordan, J.
Journal of the American Society of Hypertension 11 (8): 488-497. August 2017

Anti-diabetic effect of the ethyl acetate fraction of Clerodendrum volubile: protocatechuic acid suppresses phagocytic oxidative burst and modulates inflammatory cytokines.
Erukainure, O.L., Hafizur, R.M., Choudhary, M.I., Adhikari, A., Mesaik, A.M., Atolani, O., Banerjee, P., Preissner, R., Muhammad, A. and Islam, M.S.
Biomedicine & Pharmacotherapy 86 : 307-315. February 2017

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.
Espinosa-Medina, I., Jevans, B., Boismoreau, F., Chettouh, Z., Enomoto, H., Müller, T., Birchmeier, C., Burns, Alan J and Brunet, J.F.
Proceedings of the National Academy of Sciences of the United States of America 114 (45): 11980-11985. 7 November 2017

Parvalbumin-expressing GABAergic neurons in primary motor cortex signal reaching.
Estebanez, L., Hoffmann, D., Voigt, B.C. and Poulet, J.F.A.
Cell Reports 20 (2): 308-318. 11 July 2017

Caloric restriction is more efficient than physical exercise to protect from cisplatin nephrotoxicity via PPAR-alpha activation.
Estrela, G.R., Wasinski, F., Batista, R.O., Hiyane, M.I., Felizardo, R.J.F., Cunha, F., de Almeida, D.C., Malheiros, D.M.A.C., Camara, N.O.S., Barros, C.C., Bader, M. and Araujo, R.C.
Frontiers in Physiology 8 : 116. 2 March 2017

MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells.
Estrela, G.R., Wasinski, F., Felizardo, R.J.F., Souza, L.L., Camara, N.O.S., Bader, M. and Araujo, R.C.
Molecular and Cellular Biochemistry 428 (1): 101-108. April 2017

Gene silencing and a novel monoallelic expression pattern in distinct CD177 neutrophil subsets.
Eulenberg-Gustavus, C., Bähring, S., Maass, P., Luft, F.C. and Kettritz, R.
Journal of Experimental Medicine 214 (7): 2089-2101. 3 July 2017

Detecting markers of therapy-induced senescence in cancer cells.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1534 : 41-52. 2017

Imaging activity-dependent signaling dynamics at the neuronal synapse using FRET-based biosensors.
Farsi, Z. and Woehler, A.
Methods in Molecular Biology 1538 : 261-275. 2017

Vitamin D supplementation reduces some AT1-AA induced downstream targets implicated in preeclampsia including hypertension.
Faulkner, J.L., Amaral, L.M., Cornelius, D.C., Cunningham, M.W., Ibrahim, T., Heep, A., Campbell, N., Usry, N., Wallace, K., Herse, F., Dechend, R. and LaMarca, B.D.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 312 (1): R125-R131. 1 January 2017

Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination.
Fazal, S.V., Gomez-Sanchez, J.A., Wagstaff, L.J., Musner, N., Otto, G., Janz, M., Mirsky, R. and Jessen, K.R.
Journal of Neuroscience 37 (50): 12297-12313. 13 December 2017

A TUBB6 mutation is associated with autosomal dominant non-progressive congenital facial palsy, bilateral ptosis and velopharyngeal dysfunction.
Fazeli, W., Herkenrath, P., Stiller, B., Neugebauer, A., Fricke, J., Lang-Roth, R., Nürnberg, G., Thoenes, M., Becker, J., Altmüller, J., Volk, A.E., Kubisch, C. and Heller, R.
Human Molecular Genetics 26 (20): 4055-4066. 15 October 2017

Diabetes is associated with risk of postoperative cognitive dysfunction: a meta-analysis.
Feinkohl, I., Winterer, G. and Pischon, T.
Diabetes/Metabolism Research and Reviews 33 (5): e2884. July 2017

Cognitive reserve and the risk of postoperative cognitive dysfunction: a systematic review and meta-analysis.
Feinkohl, I., Winterer, G., Spies, C.D. and Pischon, T.
Deutsches Aerzteblatt International 114 (7): 110-107. 17 February 2017

Glucagon-producing cells are increased in Mas-deficient mice.
Felix Braga, J., Ravizzoni Dartora, D., Alenina, N., Bader, M. and Santos, R.A.S.
Endocrine Connections 6 (1): 27-32. January 2017

Insulin regulates astrocytic glucose handling through cooperation with IGF-I.
Fernandez, A.M., Hernandez-Garzón, E., Perez-Domper, P., Perez-Alvarez, A., Mederos, S., Matsui, T., Santi, A., Trueba-Saiz, A., Garcia-Guerra, L., Pose-Utrilla, J., Fielitz, J., Olson, E.N., Fernandez de la Rosa, R., Garcia Garcia, L., Pozo, M.A., Iglesias, T., Araque, A., Soya, H., Perea, G., Martin, E.D. and Torres Aleman, I.
Diabetes 66 (1): 64-74. January 2017

RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.
Ferrai, C., Torlai Triglia, E., Risner-Janiczek, J.R., Rito, T., Rackham, O.J.L., De Santiago, I., Kukalev, A., Nicodemi, M., Akalin, A., Li, M., Ungless, M.A. and Pombo, A.
Molecular Systems Biology 13 (10): 946. 16 October 2017

A chemical disruptor of the ClpX chaperone complex attenuates the virulence of multidrug-resistant Staphylococcus aureus.
Fetzer, C., Korotkov, V.S., Thänert, R., Lee, K.M., Neuenschwander, M., von Kries, J.P., Medina, E. and Sieber, S.A.
Angewandte Chemie International Edition 56 (49): 15746-15750. 4 December 2017

Animal models for personalized treatment options.
Fichtner, I., Klinghammer, K., Behrens, D., Flechsig, S., Rolff, J., Becker, M., Wulf-Goldenberg, A., Stecklum, M., Rivera, M., Brzezicha, B., Jandrig, B. and Hoffmann, J.
International Journal of Clinical Pharmacology and Therapeutics 55 (8): 698-700. August 2017

Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example.
Fingleton, B., Lange, K., Caldwell, B. and Bankaitis, K.V.
Clinical and Experimental Metastasis 34 (8): 443-447. December 2017

Evaluation of cognitive deficits and structural hippocampal damage in encephalitis with leucine-rich, glioma-inactivated 1 antibodies.
Finke, C., Prüss, H., Heine, J., Reuter, S., Kopp, U.A., Wegner, F., Then Bergh, F., Koch, S., Jansen, O., Münte, T., Deuschl, G., Ruprecht, K., Stöcker, W., Wandinger, K.P., Paul, F. and Bartsch, T.
JAMA Neurology 74 (1): 50-59. January 2017

Immunomodulatory molecules in renal cell cancer: CD80 and CD86 are expressed on tumor cells.
Flörcken, A., Johannsen, M., Nguyen-Hoai, T., Gerhardt, A., Miller, K., Dörken, B., Pezzutto, A., Westermann, J. and Jöhrens, K.
International Journal of Clinical and Experimental Pathology 10 (2): 1443-1454. 15 February 2017

Phenotype of antigen unexperienced T(H) cells in the inflamed central nervous system in experimental autoimmune encephalomyelitis.
Franck, S., Paterka, M., Birkenstock, J., Zipp, F., Siffrin, V. and Witsch, E.
Journal of Neuroimmune Pharmacology 12 (2): 305-313. June 2017

Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer.
Francy, C.A., Clinton, R.W., Froehlich, C., Murphy, C. and Mears, J.A.
Scientific Reports 7 (1): 10744. 6 September 2017

Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Frischauf, I., Litviňuková, M., Schober, R., Zayats, V., Svobodova, B., Bonhenry, D., Lunz, V., Cappello, S., Tociu, L., Reha, D., Stallinger, A., Hochreiter, A., Pammer, T., Butorac, C., Muik, M., Groschner, K., Bogeski, I., Ettrich, R.H., Romanin, C. and Schindl, R.
Science Signaling 10 (507): eaao0358. 28 November 2017

Long-term PEDF release in rat iris and retinal epithelial cells after Sleeping Beauty transposon-mediated gene delivery.
Garcia-Garcia, L., Recalde, S., Hernandez, M., Bezunartea, J., Rodriguez-Madoz, J.R., Johnen, S., Diarra, S., Marie, C., Izsvák, Z., Ivics, Z., Scherman, D., Kropp, M., Thumann, G., Prosper, F., Fernandez-Robredo, P. and Garcia-Layana, A.
Molecular Therapy - Nucleic Acids 9 : 1-11. 15 December 2017

Biocompatibility and characterization of polyglycerol-based thermoresponsive nanogels designed as novel drug-delivery systems and their intracellular localization in keratinocytes.
Gerecke, C., Edlich, A., Giulbudagian, M., Schumacher, F., Zhang, N., Said, A., Yealland, G., Lohan, S.B., Neumann, F., Meinke, M.C., Ma, N., Calderón, M., Hedtrich, S., Schäfer-Korting, M. and Kleuser, B.
Nanotoxicology 11 (2): 267-277. March 2017

Precision oncology for acute myeloid leukemia using a knowledge bank approach.
Gerstung, M., Papaemmanuil, E., Martincorena, I., Bullinger, L., Gaidzik, V.I., Paschka, P., Heuser, M., Thol, F., Bolli, N., Ganly, P., Ganser, A., McDermott, U., Döhner, K., Schlenk, R.F., Döhner, H. and Campbell, P.J.
Nature Genetics 49 (3): 332-340. March 2017

EphrinB2 activation enhances vascular repair mechanisms and reduces brain swelling after mild cerebral ischemia.
Ghori, A., Freimann, F.B., Nieminen-Kelhae, M., Kremenetskaia, I., Gertz, K., Endres, M. and Vajkoczy, P.
Arteriosclerosis Thrombosis and Vascular Biology 37 (5): 867-878. May 2017

Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis.
Gieß, R.M., Pfuhl, C., Behrens, J.R., Rasche, L., Freitag, E., Khalighy, N., Otto, C., Wuerfel, J., Brandt, A.U., Hofmann, J., Eberspächer, B., Bellmann-Strobl, J., Paul, F. and Ruprecht, K.
PLoS ONE 12 (4): e0175279. 7 April 2017

Antibodies to signaling molecules and receptors in Alzheimer's disease are associated with psychomotor slowing, depression, and poor visuospatial function.
Giil, L.M., Vedeler, C.A., Kristoffersen, E.K., Nordrehaug, J.E., Heidecke, H., Dechend, R., Schulze-Forster, K., Muller, D.N., von Goetze, V.S., Cabral-Marques, O., Riemekasten, G., Vogelsang, P., Nygaard, S., Lund, A. and Aarsland, D.
Journal of Alzheimer's Disease 59 (3): 929-939. 29 July 2017

Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
Gillissen, B., Richter, A., Richter, A., Preissner, R., Schulze-Osthoff, K., Essmann, F. and Daniel, P.T.
Journal of Biological Chemistry 292 (16): 6478-6492. 21 April 2017

A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use.
Gleicher, N., Metzger, J., Croft, G., Kushnir, V.A., Albertini, D.F. and Barad, D.H.
Reproductive Biology and Endocrinology 15 (1): 33. 27 April 2017

Parallel habitat acclimatization is realized by the expression of different genes in two closely related salamander species (genus Salamandra).
Goedbloed, D.J., Czypionka, T., Altmüller, J., Rodriguez, A., Küpfer, E., Segev, O., Blaustein, L., Templeton, A.R., Nolte, A.W. and Steinfartz, S.
Heredity 119 (6): 429-437. December 2017

Aggregation-induced changes in the chemical exchange saturation transfer (CEST) signals of proteins.
Goerke, S., Milde, K.S., Bukowiecki, R., Kunz, P., Klika, K.D., Wiglenda, T., Mogk, A., Wanker, E.E., Bukau, B., Ladd, M.E., Bachert, P. and Zaiss, M.
NMR in Biomedicine 30 (1): e3665. January 2017

Neue Entwicklungen auf dem Gebiet der Präeklampsie [New developments in the field of preeclampsia].
Golic, M. and Dechend, R.
Nephrologe 12 (2): 115-120. March 2017

Late-onset Bartter syndrome type II.
Gollasch, B., Anistan, Y.M., Canaan-Kühl, S. and Gollasch, M.
Clinical Kidney Journal 10 (5): 594-599. October 2017

RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.
Gottlieb, A., Althoff, K., Grunewald, L., Thor, T., Odersky, A., Schulte, M., Deubzer, H.E., Heukamp, L., Eggert, A., Schramm, A., Schulte, J.H. and Künkele, A.
Oncotarget 8 (17): 27882-27891. 25 April 2017

A gene regulatory network balances neural and mesoderm specification during vertebrate trunk development.
Gouti, M., Delile, J., Stamataki, D., Wymeersch, F.J., Huang, Y., Kleinjung, J., Wilson, V. and Briscoe, J.
Developmental Cell 41 (3): 243-261. 8 May 2017

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence.
Griger, J., Schneider, R., Lahmann, I., Schöwel, V., Keller, C., Spuler, S., Nazare, M. and Birchmeier, C.
eLife 6 : e21552. 2 May 2017

easyGWAS: a cloud-based platform for comparing the results of genome-wide association studies.
Grimm, D.G., Roqueiro, D., Salomé, P.A., Kleeberger, S., Greshake, B., Zhu, W., Liu, C., Lippert, C., Stegle, O., Schölkopf, B., Weigel, D. and Borgwardt, K.M.
Plant Cell 29 (1): 5-19. January 2017

Maximum walking speed in multiple sclerosis assessed with visual perceptive computing.
Grobelny, A., Behrens, J.R., Mertens, S., Otte, K., Mansow-Model, S., Krüger, T., Gusho, E., Bellmann-Strobl, J., Paul, F., Brandt, A.U. and Schmitz-Hübsch, T.
PLoS ONE 12 (12): e0189281. 15 December 2017

Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit.
Grosheva, A.S., Zharkov, D.O., Stahl, J., Gopanenko, Al.V., Tupikin, A.E., Kabilov, M.R., Graifer, D.M. and Karpova, G.G.
Nucleic Acids Research 45 (7): 3833-3843. 20 April 2017

The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy.
Grüning, B.A., Fallmann, J., Yusuf, D., Will, S., Erxleben, A., Eggenhofer, F., Houwaart, T., Batut, B., Videm, P., Bagnacani, A., Wolfien, M., Lott, S.C., Hoogstrate, Y., Hess, W.R., Wolkenhauer, O., Hoffmann, S., Akalin, A., Ohler, U., Stadler, P.F. and Backofen, R.
Nucleic Acids Research 45 (W1): W560-W566. 3 July 2017

Technical considerations for the use of CRISPR/Cas9 in hematology research.
Gundry, M.C., Dever, D.P., Yudovich, D., Bauer, D.E., Haas, S., Wilkinson, A.C. and Singbrant, S.
Experimental Hematology 54 : 4-11. October 2017

Protective function of Ahnak1 in vascular healing after wire injury.
Haase, N., Rüder, C., Haase, H., Kamann, S., Kouno, M., Morano, I., Dechend, R., Zohlnhöfer, D. and Haase, T.
Journal of Vascular Research 54 (3): 131-142. May 2017

Deep brain stimulation during early adolescence prevents microglial alterations in a model of maternal immune activation.
Hadar, R., Dong, L., Del-Valle-Anton, L., Gueneykaya, D., Voget, M., Edemann-Callesen, H., Schweibold, R., Djodari-Irani, A., Goetz, T., Ewing, S., Kettenmann, H., Wolf, S.A. and Winter, C.
Brain, Behavior and Immunity 63 : 71-80. 7 July 2017

McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.
Hafez, D., Karabacak, A., Krueger, S., Hwang, Y.C., Wang, L.S., Zinzen, R.P. and Ohler, U.
Genome Biology 18 (1): 199. 26 October 2017

Identification of the flotillin-1/2 heterocomplex as a target of autoantibodies in bona fide multiple sclerosis.
Hahn, S., Trendelenburg, G., Scharf, M., Denno, Y., Brakopp, S., Teegen, B., Probst, C., Wandinger, K.P., Buttmann, M., Haarmann, A., Szabados, F., Vom Dahl, M., Kuempfel, T., Eichhorn, P., Gold, H., Paul, F., Jarius, S., Melzer, N., Stöcker, W. and Komorowski, L.
Journal of Neuroinflammation 14 (1): 123. 23 June 2017

Germline mutation status, pathological complete response, and disease-free survival in triple-negative breast cancer: secondary analysis of the GeparSixto randomized clinical trial.
Hahnen, E., Lederer, B., Hauke, J., Loibl, S., Kröber, S., Schneeweiss, A., Denkert, C., Fasching, P.A., Blohmer, J.U., Jackisch, C., Paepke, S., Gerber, B., Kümmel, S., Schem, C., Neidhardt, G., Huober, J., Rhiem, K., Costa, S., Altmüller, J., Hanusch, C., Thiele, H., Müller, V., Nürnberg, P., Karn, T., Nekljudova, V., Untch, M., von Minckwitz, G. and Schmutzler, R.K.
JAMA Oncology 3 (10): 1378-1385. 1 October 2017

Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation.
Hammer, A., Schliep, A., Jörg, S., Haghikia, A., Gold, R., Kleinewietfeld, M., Müller, D.N. and Linker, R.A.
Journal of Neuroinflammation 14 (1): 184. 12 September 2017

3 Tesla (23)Na magnetic resonance imaging during acute kidney injury.
Hammon, M., Grossmann, S., Linz, P., Seuss, H., Hammon, R., Rosenhauer, D., Janka, R., Cavallaro, A., Luft, F.C., Titze, J., Uder, M. and Dahlmann, A.
Academic Radiology 24 (9): 1086-1093. September 2017

Open source 3D multipurpose measurement system with submillimetre fidelity and first application in magnetic resonance.
Han, H., Moritz, R., Oberacker, E., Waiczies, H., Niendorf, T. and Winter, L.
Scientific Reports 7 (1): 13452. 18 October 2017

A fluorescent RNA forced-intercalation probe as a pan-selective marker for influenza A virus infection.
Haralampiev, I., Schade, M., Chamiolo, J., Jolmes, F., Prisner, S., Witkowski, P.T., Behrent, M., Hövelmann, F., Wolff, T., Seitz, O. and Herrmann, A.
ChemBioChem 18 (16): 1589-1592. 17 August 2017

Paracrine and autocrine regulation of gene expression by Wnt-inhibitor Dickkopf in wild-type and mutant hepatocytes.
Hartung, N., Benary, U., Wolf, J. and Kofahl, B.
BMC Systems Biology 11 (1): 98. 13 October 2017

Structural brain changes are associated with response of negative symptoms to prefrontal repetitive transcranial magnetic stimulation in patients with schizophrenia.
Hasan, A., Wobrock, T., Guse, B., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Cordes, J., Woelwer, W., Musso, F., Winterer, G., Gaebel, W., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Dechent, P., Malchow, B., Castro, M.F.U., Dwyer, D., Cabral, C., Kreuzer, P.M., Poeppl, T.B., Schneider-Axmann, T., Falkai, P. and Koutsouleris, N.
Molecular Psychiatry 22 (6): 857-864. June 2017

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
Hasegawa, E., Inafuku, S., Mulki, L., Okunuki, Y., Yanai, R., Smith, K.E., Kim, C.B., Klokman, G., Bielenberg, D.R., Puli, N., Falck, J.R., Husain, D., Miller, J.W., Edin, M.L., Zeldin, D.C., Lee, K.S.S., Hammock, B.D., Schunck, W.H. and Connor, K.M.
Proceedings of the National Academy of Sciences of the United States of America 114 (36): E7545-E7553. 5 September 2017

Investigating the link between MCP-1 A-2518G, RANTES G-403A, CX3CR1 V249I and MTHFR C677T gene polymorphisms and the risk of acute myocardial infarction among Egyptians.
Hashad, I.M., Abdel Rahman, M.F., Alenina, N., Bader, M. and Gad, M.Z.
Meta Gene 11 : 181-188. February 2017

Branched-chain amino acid catabolism rather than amino acids plasma concentrations is associated with diet-induced changes in insulin resistance in overweight to obese individuals.
Haufe, S., Engeli, S., Kaminski, J., Witt, H., Rein, D., Kamlage, B., Utz, W., Fuhrmann, J.C., Haas, V., Mähler, A., Schulz-Menger, J., Luft, F.C., Boschmann, M. and Jordan, J.
Nutrition Metabolism and Cardiovascular Diseases 27 (10): 858-864. October 2017

NHE1 expression at wound margins increases time-dependently during physiological healing.
Haverkampf, S., Heider, J., Weiß, K.T., Haubner, F., Ettl, T., Schreml, J., Hedtrich, S., von Süßkind-Schwendi, M., Berneburg, M., Karrer, S., Dissemond, J. and Schreml, S.
Experimental dermatology 26 (2): 124-126. February 2017

Epigenetic mechanism of FMR1 inactivation in Fragile X syndrome.
Hecht, M., Tabib, A., Kahan, T., Orlanski, S., Gropp, M., Tabach, Y., Yanuka, O., Benvenisty, N., Keshet, I. and Cedar, H.
International Journal of Developmental Biology 61 (3-5): 285-292. 2017

What should a person with relapsing-remitting multiple sclerosis know? - Focus group and survey data of a risk knowledge questionnaire (RIKNO 2.0).
Heesen, C., Pöttgen, J., Rahn, A.C., Liethmann, K., Kasper, J., Vahter, L., Drulovic, J., Van Nunen, A., Wilkie, D., Beckmann, Y., Paul, F., Köpke, S., Giordano, A. and Solari, A.
Multiple Sclerosis and Related Disorders 18 : 186-195. November 2017

Assessment of imatinib as first-line treatment of chronic myeloid leukemia: 10-year survival results of the randomized CML study IV and impact of non-CML determinants.
Hehlmann, R., Lauseker, M., Saußele, S., Pfirrmann, M., Krause, S., Kolb, H.J., Neubauer, A., Hossfeld, D.K., Nerl, C., Gratwohl, A., Baerlocher, G.M., Heim, D., Brümmendorf, T.H., Fabarius, A., Haferlach, C., Schlegelberger, B., Müller, M.C., Jeromin, S., Proetel, U., Kohlbrenner, K., Voskanyan, A., Rinaldetti, S., Seifarth, W., Spieß, B., Balleisen, L., Goebeler, M.C., Hänel, M., Ho, A., Dengler, J., Falge, C., Kanz, L., Kremers, S., Burchert, A., Kneba, M., Stegelmann, F., Köhne, C.A., Lindemann, H.W., Waller, C.F., Pfreundschuh, M., Spiekermann, K., Berdel, W.E., Müller, L., Edinger, M., Mayer, J., Beelen, D.W., Bentz, M., Link, H., Hertenstein, B., Fuchs, R., Wernli, M., Schlegel, F., Schlag, R., de Wit, M., Trümper, L., Hebart, H., Hahn, M., Thomalla, J., Scheid, C., Schafhausen, P., Verbeek, W., Eckart, M.J., Gassmann, W., Pezzutto, A., Schenk, M., Brossart, P., Geer, T., Bildat, S., Schäfer, E., Hochhaus, A. and Hasford, J.
Leukemia 31 (11): 2398-2406. November 2017

Retinol saturase coordinates liver metabolism by regulating ChREBP activity.
Heidenreich, S., Witte, N., Weber, P., Goehring, I., Tolkachov, A., von Loeffelholz, C., Döcke, S., Bauer, M., Stockmann, M., Pfeiffer, A.F.H., Birkenfeld, A.L., Pietzke, M., Kempa, S., Muenzner, M. and Schupp, M.
Nature Communications 8 (1): 384. 30 August 2017

Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.
Heinig, M., Adriaens, M.E., Schafer, S., van Deutekom, H.W.M., Lodder, E.M., Ware, J.S., Schneider, V., Felkin, L.E., Creemers, E.E., Meder, B., Katus, H.A., Rühle, F., Stoll, M., Cambien, F., Villard, E., Charron, P., Varro, A., Bishopric, N.H., George, A.L., Dos Remedios, C., Moreno-Moral, A., Pesce, F., Bauerfeind, A., Rüschendorf, F., Rintisch, C., Petretto, E., Barton, P.J., Cook, S.A., Pinto, Y.M., Bezzina, C.R. and Hubner, N.
Genome Biology 18 (1): 170. 14 September 2017

ssHMM: extracting intuitive sequence-structure motifs from high-throughput RNA-binding protein data.
Heller, D., Krestel, R., Ohler, U., Vingron, M. and Marsico, A.
Nucleic Acids Research 45 (19): 11004-11018. 2 November 2017

Predictive significance of the European LeukemiaNet classification of genetic aberrations in patients with acute myeloid leukemia undergoing allogeneic stem cell transplantation.
Hemmati, P.G., Vuong, L.G., Terwey, T.H., Jehn, C.F., Le Coutre, P., Penack, O., Na, I.K., Dörken, B. and Arnold, R.
European Journal of Haematology 98 (2): 160-168. February 2017

Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative.
Hendriks, H.R., Govaerts, A.S., Fichtner, I., Burtles, S., Westwell, A.D. and Peters, G.J.
British Journal of Cancer 117 (2): 195-202. 11 July 2017

Prenatal mechanistic target of rapamycin complex 1 (mTORC1) inhibition by rapamycin treatment of pregnant mice causes intrauterine growth restriction and alters postnatal cardiac growth, morphology, and function.
Hennig, M., Fiedler, S., Jux, C., Thierfelder, L. and Drenckhahn, J.D.
Journal of the American Heart Association 6 (8): e005506. 4 August 2017

The ClC-K2 chloride channel is critical for salt handling in the distal nephron.
Hennings, J.C., Andrini, O., Picard, N., Paulais, M., Huebner, A.K., Lopez Cayuqueo, I.K., Bignon, Y., Keck, M., Cornière, N., Böhm, D., Jentsch, T.J., Chambrey, R., Teulon, J., Hübner, C.A. and Eladari, D.
Journal of the American Society of Nephrology 28 (1): 209-217. January 2017

PGBD5 promotes site-specific oncogenic mutations in human tumors.
Henssen, A.G., Koche, R., Zhuang, J., Jiang, E., Reed, C., Eisenberg, A., Still, E., MacArthur, I.C., Rodriguez-Fos, E., Gonzalez, S., Puiggròs, M., Blackford, A.N., Mason, C.E., de Stanchina, E., Gönen, M., Emde, A.K., Shah, M., Arora, K., Reeves, C., Socci, N.D., Perlman, E., Antonescu, C.R., Roberts, C.W.M., Steen, H., Mullen, E., Jackson, S.P., Torrents, D., Weng, Z., Armstrong, S.A. and Kentsis, A.
Nature Genetics 49 (7): 1005-1014. July 2017

Targeting tachykinin receptors in neuroblastoma.
Henssen, A.G., Odersky, A., Szymansky, A., Seiler, M., Althoff, K., Beckers, A., Speleman, F., Schäfers, S., De Preter, K., Astrahanseff, K., Struck, J., Schramm, A., Eggert, A., Bergmann, A. and Schulte, J.H.
Oncotarget 8 (1): 430-443. 3 January 2017

Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.
Henssen, A.G., Reed, C., Jiang, E., Garcia, H.D., von Stebut, J., MacArthur, I.C., Hundsdoerfer, P., Kim, J.H., de Stanchina, E., Kuwahara, Y., Hosoi, H., Ganem, N.J., Dela Cruz, F., Kung, A.L., Schulte, J.H., Petrini, J.H. and Kentsis, A.
Science Translational Medicine 9 (414): eaam9078. 1 November 2017

Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells.
Herce, H.D., Schumacher, D., Schneider, A.F.L., Ludwig, A.K., Mann, F.A., Fillies, M., Kasper, M.-A., Reinke, S., Krause, E., Leonhardt, H., Cardoso, M.C. and Hackenberger, C.P.R.
Nature Chemistry 9 (8): 762-771. August 2017

Frequency of exercise-induced ST-T-segment deviations and cardiac arrhythmias in recreational endurance athletes during a marathon race: results of the prospective observational Berlin Beat of Running study.
Herm, J., Toepper, A., Wutzler, A., Kunze, C., Kruell, M., Brechtel, L., Lock, J., Fiebach, J.B., Heuschmann, P.U., Haverkamp, W., Endres, M., Jungehulsing, G.J. and Haeusler, K.G.
BMJ Open 7 (8): e015798. 3 August 2017

Genetic identification of a hindbrain nucleus essential for innate vocalization.
Hernandez-Miranda, L.R., Ruffault, P.L., Bouvier, J.C., Murray, A.J., Morin-Surun, M.P., Zampieri, N., Cholewa-Waclaw, J.B., Ey, E., Brunet, J.F., Champagnat, J., Fortin, G. and Birchmeier, C.
Proceedings of the National Academy of Sciences of the United States of America 114 (30): 8095-8100. 25 July 2017

RNA-seq based transcriptome analysis of the type I interferon host response upon vaccinia virus infection of mouse cells.
Hernáez, B., Alonso, G., Alonso-Lobo, J.M., Rastrojo, A., Fischer, C., Sauer, S., Aguado, B. and Alcamí, A.
Journal of Immunology Research 2017 : 5157626. 9 February 2017

CTLA4 promotes Tyk2-STAT3 dependent B-cell oncogenecity.
Herrmann, A., Lahtz, C., Nagao, T., Song, J.Y., Chan, W.C., Lee, H., Yue, C., Look, T., Muelfarth, R., Li, W., Jenkins, K., Williams, J., Budde, L.E., Forman, S.J., Kwak, L.W., Blankenstein, T. and Yu, H.
Cancer Research 77 (18): 5118-5128. 15 September 2017

Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair.
Herzig, J.K., Bullinger, L., Tasdogan, A., Zimmermann, P., Schlegel, M., Teleanu, V., Weber, D., Rücker, F.G., Paschka, P., Dolnik, A., Schneider, E., Kuchenbauer, F., Heidel, F.H., Buske, C., Döhner, H., Döhner, K. and Gaidzik, V.I.
Oncotarget 8 (56): 95038-95053. 10 November 2017

Partitioned learning of deep Boltzmann machines for SNP data.
Hess, M., Lenz, S., Blätte, T.J., Bullinger, L. and Binder, H.
Bioinformatics 33 (20): 3173-3180. October 2017

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions.
Hessenberger, M., Zerbes, R.M., Rampelt, H., Kunz, S., Xavier, A.H., Purfürst, B., Lilie, H., Pfanner, N., van der Laan, M. and Daumke, O.
Nature Communications 8 : 15258. 31 May 2017

Immunoproteasome subunit β5i/LMP7-deficiency in atherosclerosis.
Hewing, B., Ludwig, A., Dan, C., Poetzsch, M., Hannemann, C., Petry, A., Lauer, D., Görlach, A., Kaschina, E., Müller, D.N., Baumann, G., Stangl, V., Stangl, K. and Wilck, N.
Scientific Reports 7 (1): 13342. 17 October 2017

Evaluating the impact of genetic and epigenetic aberrations on survival and response in acute myeloid leukemia patients receiving epigenetic therapy.
Hiller, J.K., Schmoor, C., Gaidzik, V.I., Schmidt-Salzmann, C., Yalcin, A., Abdelkarim, M., Blagitko-Dorfs, N., Döhner, K., Bullinger, L., Duyster, J., Lübbert, M. and Hackanson, B.
Annals of Hematology 96 (4): 559-565. April 2017

Small molecules targeting human N-acetylmannosamine kinase.
Hinderlich, S., Neuenschwander, M., Wratil, P.R., Oder, A., Lisurek, M., Nguyen, L.D., von Kries, J.P. and Hackenberger, C.P.R.
ChemBioChem 18 (13): 1279-1285. 4 July 2017

Systemic virus infections differentially modulate cell cycle state and functionality of long-term hematopoietic stem cells in vivo.
Hirche, C., Frenz, T., Haas, S.F., Döring, M., Borst, K., Tegtmeyer, P.K., Brizic, I., Jordan, S., Keyser, K., Chhatbar, C., Pronk, E., Lin, S., Messerle, M., Jonjic, S., Falk, C.S., Trumpp, A., Essers, M.A.G. and Kalinke, U.
Cell Reports 19 (11): 2345-2356. 13 June 2017

Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia.
Hirsch, S., Blätte, T.J., Grasedieck, S., Cocciardi, S., Rouhi, A., Jongen-Lavrencic, M., Paschka, P., Krönke, J., Gaidzik, V.I., Döhner, H., Schlenk, R.F., Kuchenbauer, F., Döhner, K., Dolnik, A. and Bullinger, L.
Haematologica 102 (12): 2039-2047. December 2017

Placental expression of sFlt-1 and PlGF in early preeclampsia vs. early IUGR vs. age-matched healthy pregnancies.
Hoeller, A., Ehrlich, L., Golic, M., Herse, F., Perschel, F.H., Siwetz, M., Henrich, W., Dechend, R., Huppertz, B. and Verlohren, S.
Hypertension in Pregnancy 36 (2): 151-160. May 2017

Response evaluation in head and neck oncology: definition and prediction.
Hoffmann, T.K., Schuler, P.J., Laban, S., Grässlin, R., Beer, M., Beer, A.J., Friebe-Hoffmann, U., Bullinger, L., Möller, P. and Wiegel, T.
ORL 79 (1-2): 14-23. February 2017

Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS).
Horpaopan, S., Kirfel, J., Peters, S., Kloth, M., Hüneburg, R., Altmüller, J., Drichel, D., Odenthal, M., Kristiansen, G., Strassburg, C., Nattermann, J., Hoffmann, P., Nürnberg, P., Büttner, R., Thiele, H., Kahl, P., Spier, I. and Aretz, S.
Hereditary Cancer in Clinical Practice 15 : 22. 29 November 2017

Role of Müller cell cytochrome P450 2c44 in murine retinal angiogenesis.
Hu, J., Geyer, A., Dziumbla, S., Awwad, K., Zeldin, D.C., Schunck, W.H., Popp, R., Frömel, T. and Fleming, I.
Prostaglandins & Other Lipid Mediators 133 : 93-102. November 2017

Signatures of personality on dense 3D facial images.
Hu, S., Xiong, J., Fu, P., Qiao, L., Tan, J., Jin, L. and Tang, K.
Scientific Reports 7 (1): 73. March 2017

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts.
Huang, K.L., Li, S., Mertins, P., Cao, S., Gunawardena, H.P., Ruggles, K.V., Mani, D.R., Clauser, K.R., Tanioka, M., Usary, J., Kavuri, S.M., Xie, L., Yoon, C., Qiao, J.W., Wrobel, J., Wyczalkowski, M.A., Erdmann-Gilmore, P., Snider, J.E., Hoog, J., Singh, P., Niu, B., Guo, Z., Sun, S.Q., Sanati, S., Kawaler, E., Wang, X., Scott, A., Ye, K., McLellan, M.D., Wendl, M.C., Malovannaya, A., Held, J.M., Gillette, M.A., Fenyö, D., Kinsinger, C.R., Mesri, M., Rodriguez, H., Davies, S.R., Perou, C.M., Ma, C., Townsend, R.R., Chen, X., Carr, S.A., Ellis, M.J. and Ding, L.
Nature Communications 8 : 14864. 28 March 2017

Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy.
Huang, N., Kny, M., Riediger, F., Busch, K., Schmidt, S., Luft, F.C., Slevogt, H. and Fielitz, J.
Intensive Care Medicine Experimental 5 (1): 3. 17 January 2017

SORLA attenuates EphA4 signaling and amyloid, β-induced neurodegeneration.
Huang, T.Y., Zhao, Y., Jiang, L.L., Li, X., Liu, Y., Sun, Y., Piña-Crespo, J.C., Zhu, B., Masliah, E., Willnow, T.E., Pasquale, E.B. and Xu, H.
Journal of Experimental Medicine 214 (12): 3669-3685. 4 December 2017

Myocardial T(2)(*) mapping at ultrahigh magnetic fields: in vivo myocardial tissue characterization and assessment of cardiac physiology with magnetic resonance imaging.
Huelnhagen, T., Flemming, B., Seeliger, E., Schulz-Menger, J. and Niendorf, T.
Current Directions in Biomedical Engineering 3 (2): 433-436. September 2017

Myocardial effective transverse relaxation time T(2)* correlates with left ventricular wall thickness: a 7.0 T MRI study.
Huelnhagen, T., Hezel, F., Serradas Duarte, T., Pohlmann, A., Oezerdem, C., Flemming, B., Seeliger, E., Prothmann, M., Schulz-Menger, J. and Niendorf, T.
Magnetic Resonance in Medicine 77 (6): 2381-2389. June 2017

Myocardial T(2)* mapping with ultrahigh field magnetic resonance: physics and frontier applications.
Huelnhagen, T., Paul, K., Ku, M.C., Serradas Duarte, T. and Niendorf, T.
Frontiers in Physics 5 : 22. June 2017

Fast genome-wide functional annotation through orthology assignment by eggNOG-mapper.
Huerta-Cepas, J., Forslund, K., Coelho, L.P., Szklarczyk, D., Jensen, L.J., von Mering, C. and Bork, P.
Molecular Biology and Evolution 34 (8): 2115-2122. 1 August 2017

Activating de novo mutations in NFE2L2 encoding NRF2 cause a multisystem disorder.
Huppke, P., Weissbach, S., Church, J.A., Schnur, R., Krusen, M., Dreha-Kulaczewski, S., Kühn-Velten, W.N., Wolf, A., Huppke, B., Millan, F., Begtrup, A., Almusafri, F., Thiele, H., Altmüller, J., Nürnberg, P., Müller, M. and Gärtner, J.
Nature Communications 8 (1): 818. 10 October 2017

INSERT: A novel clinical scanner for simultaneous SPECT/MRI brain studies.
Hutton, B.F., Erlandsson, K., Salvado, D., Occhipinti, M., Papp, Z., Tolgyesi, B., Willems, J., Piemonte, C., Carminati, M., Bukki, T., Legrady, G., Kuehne, A., Nyitrai, Z., Niendorf, T., Van Mullekom, P., Waiczies, H., Nagy, K., De Francesco, I., Mathe, D., Ottobrini, L., Short, S.C. and Fiorini, C.
IEEE Nuclear Science Symposium and Medical Imaging Conference : 18264611. 2017

Pilot study of psychiatric and social aspects of children and adolescents with fragile X syndrome [Pilotstudie zu psychiatrischen und sozialen Aspekten bei Kindern und Jugendlichen mit Fragilem-X-Syndrom (FRX)].
Häßler, F., Gaese, F., Colla, M., Huss, M., Kretschmar, C., Brinkman, M., Peters, H., Elstner, S., Weirich, S. and Pittrow, D.
Zeitschrift fuer Kinder- und Jugendpsychiatrie und Psychotherapie 45 (2): 141-147. March 2017

Synapsin-antibodies in psychiatric and neurological disorders: prevalence and clinical findings.
Höltje, M., Mertens, R., Schou, M.B., Saether, S.G., Kochova, E., Jarius, S., Prüss, H., Komorowski, L., Probst, C., Paul, F., Bellmann-Strobl, J., Gitler, D., Benfenati, F., Piepgras, J., Ahnert-Hilger, G. and Ruprecht, K.
Brain Behavior and Immunity 66 : 125-134. November 2017

Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy.
Ibrahim, T., Przybyl, L., Harmon, A.C., Amaral, L.M., Faulkner, J.L., Cornelius, D., Cunningham, M.W., Hünig, T., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Reproductive Immunology 78 (5): e12724. November 2017

A synthetic biology approach to probing nucleosome symmetry.
Ichikawa, Y., Connelly, C.F., Appleboim, A., Miller, T.C., Jacobi, H., Abshiru, N.A., Chou, H.J., Chen, Y., Sharma, U., Zheng, Y., Thomas, P.M., Chen, H.V., Bajaj, V., Müller, C.W., Kelleher, N.L., Friedman, N., Bolon, D.N.A., Rando, O.J. and Kaufman, P.D.
eLife 6 : e28836. 12 September 2017

Neuronal chemosensation and osmotic stress response converge in the regulation of aqp-8 in C. elegans.
Igual Gil, C., Jarius, M., von Kries, J.P. and Rohlfing, A.K.
Frontiers in Physiology 8 : 380. 9 June 2017

SIRT1 regulates macrophage self-renewal.
Imperatore, F., Maurizio, J., Vargas Aguilar, S., Busch, C.J., Favret, J., Kowenz-Leutz, E., Cathou, W., Gentek, R., Perrin, P., Leutz, A., Berruyer, C. and Sieweke, M.H.
EMBO Journal 36 (16): 2353-2372. 15 August 2017

Compound annotation in liquid chromatography/high-resolution mass spectrometry based metabolomics: robust adduct ion determination as a prerequisite to structure prediction in electrospray ionization mass spectra.
Jaeger, C., Méret, M., Schmitt, C.A. and Lisec, J.
Rapid Communications in Mass Spectrometry 31 (15): 1261-1266. 15 August 2017

24 h-accelerometry in epidemiological studies : automated detection of non-wear time in comparison to diary information.
Jaeschke, L., Luzak, A., Steinbrecher, A., Jeran, S., Ferland, M., Linkohr, B., Schulz, H. and Pischon, T.
Scientific Reports 7 (1): 2227. 22 May 2017

Tracking the evolution of non-small-cell lung cancer.
Jamal-Hanjani, M., Wilson, G.A., McGranahan, N., Birkbak, N.J., Watkins, T.B.K., Veeriah, S., Shafi, S., Johnson, D.H., Mitter, R., Rosenthal, R., Salm, M., Horswell, S., Escudero, M., Matthews, N., Rowan, A., Chambers, T., Moore, D.A., Turajlic, S., Xu, H., Lee, S.-M., Forster, M.D., Ahmad, T., Hiley, C.T., Abbosh, C., Falzon, M., Borg, E., Marafioti, T., Lawrence, D., Hayward, M., Kolvekar, S., Panagiotopoulos, N., Janes, S.M., Thakrar, R., Ahmed, A., Blackhall, F., Summers, Y., Shah, R., Joseph, L., Quinn, A.M., Crosbie, P.A., Naidu, B., Middleton, G., Langman, G., Trotter, S., Nicolson, M., Remmen, H., Kerr, K., Chetty, M., Gomersall, L., Fennell, D.A., Nakas, A., Rathinam, S., Anand, G., Khan, S., Russell, P., Ezhil, V., Ismail, B., Irvin-Sellers, M., Prakash, V., Lester, J.F., Kornaszewska, M., Attanoos, R., Adams, H., Davies, H., Dentro, S., Taniere, P., O'Sullivan, B., Lowe, H.L., Hartley, J.A., Iles, N., Bell, H., Ngai, Y., Shaw, J.A., Herrero, J., Szallasi, Z., Schwarz, R.F., Stewart, A., Quezada, S.A., Le Quesne, J., Van Loo, P., Dive, C., Hackshaw, A. and Swanton, C.
New England Journal of Medicine 376 (22): 2109-2121. 1 June 2017

Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis.
Jarius, S., König, F.B., Metz, I., Ruprecht, K., Paul, F., Brück, W. and Wildemann, B.
Journal of Neuroinflammation 14 (1): 171. 29 August 2017

Tricellulin is a target of the ubiquitin ligase Itch.
Jennek, S., Mittag, S., Reiche, J., Westphal, J.K., Seelk, S., Dörfel, M.J., Pfirrmann, T., Friedrich, K., Schütz, A., Heinemann, U. and Huber, O.
Annals of the New York Academy of Sciences 1397 (1): 157-168. June 2017

Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Jerke, U., Marino, S.F., Daumke, O. and Kettritz, R.
Scientific Reports 7 : 43328. 27 February 2017

TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression.
Jiang, C., Zhu, Y., Zhou, Z., Gumin, J., Bengtsson, L., Wu, W., Songyang, Z., Lang, F.F. and Lin, X.
Oncogene 36 (20): 2813-2823. 18 May 2017

Metabolic anchor reactions for robust biorefining.
Jouhten, P., Huerta-Cepas, J., Bork, P. and Patil, K.R.
Metabolic Engineering 40 : 1-4. March 2017

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.
Juneja, M., Kobelt, D., Walther, W., Voss, C., Smith, J., Specker, E., Neuenschwander, M., Gohlke, B.O., Dahlmann, M., Radetzki, S., Preissner, R., von Kries, J.P., Schlag, P.M. and Stein, U.
PLoS Biology 15 (6): e2000784. 1 June 2017

Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes.
Jäger, S., Wahl, S., Kröger, J., Sharma, S., Hoffmann, P., Floegel, A., Pischon, T., Prehn, C., Adamski, J., Müller-Nurasyid, M., Waldenberger, M., Strauch, K., Peters, A., Gieger, C., Suhre, K., Grallert, H., Boeing, H., Schulze, M.B. and Meidtner, K.
Scientific Reports 7 (1): 6037. 20 July 2017

Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction.
Järve, A., Mühlstedt, S., Qadri, F., Nickl, B., Schulz, H., Hübner, N., Özcelik, C. and Bader, M.
FASEB Journal 31 (2): 556-568. February 2017

Development of mouse model systems of germinal center lymphomas.
Kabrani, E. and Sander, S.
Methods in Molecular Biology 1623 : 233-242. 2017

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.
Kammertoens, T., Friese, C., Arina, A., Idel, C., Briesemeister, D., Rothe, M., Ivanov, A., Szymborska, A., Patone, G., Kunz, S., Sommermeyer, D., Engels, B., Leisegang, M., Textor, A., Fehling, H.J., Fruttiger, M., Lohoff, M., Herrmann, A., Yu, H., Weichselbaum, R., Uckert, W., Hübner, N., Gerhardt, H., Beule, D., Schreiber, H. and Blankenstein, T.
Nature 545 (7652): 98-102. 4 May 2017

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression.
Kar, G., Kim, J.K., Kolodziejczyk, A.A., Natarajan, K.N., Torlai Triglia, E., Mifsud, B., Elderkin, S., Marioni, J.C., Pombo, A. and Teichmann, S.A.
Nature Communications 8 (1): 36. 26 June 2017

The Drosophila embryo at single-cell transcriptome resolution.
Karaiskos, N., Wahle, P., Alles, J., Boltengagen, A., Ayoub, S., Kipar, C., Kocks, C., Rajewsky, N. and Zinzen, R.P.
Science 358 (6360): 194-199. 13 October 2017

Efferocytosis of pathogen-infected cells.
Karaji, N. and Sattentau, Q.J.
Frontiers in Immunology 8 : 1863. 22 December 2017

A comprehensive TALEN-based knockout library for generating human induced pluripotent stem cell-based models for cardiovascular diseases.
Karakikes, I., Termglinchan, V., Cepeda, D.A., Lee, J., Diecke, S., Hendel, A., Itzhaki, I., Ameen, M., Shrestha, R., Wu, H., Ma, N., Shao, N.Y., Seeger, T., Woo, N.A., Wilson, K.D., Matsa, E., Porteus, M.H., Sebastiano, V. and Wu, J.C.
Circulation Research 120 (10): 1561-1571. 12 May 2017

Identifying ischemic stroke associated with cancer: a multiple model derived from a case-control analysis.
Kassubek, R., Bullinger, L., Kassubek, J., Dreyhaupt, J., Ludolph, A.C., Althaus, K. and Lewerenz, J.
Journal of Neurology 264 (4): 781-791. April 2017

mRNA interactome capture in mammalian cells.
Kastelic, N. and Landthaler, M.
Methods 126 : 38-43. 15 August 2017

Anti-aquaporin-4 titer is not predictive of disease course in neuromyelitis optica spectrum disorder: a multicenter cohort study.
Kessler, R.A., Mealy, M.A., Jimenez-Arango, J.A., Quan, C., Paul, F., López, R., Hopkins, S. and Levy, M.
Multiple Sclerosis and Related Disorders 17 : 198-201. October 2017

A deep intronic CLRN1 (USH3A) founder mutation generates an aberrant exon and underlies severe Usher syndrome on the Arabian Peninsula.
Khan, A.O., Becirovic, E., Betz, C., Neuhaus, C., Altmüller, J., Maria Riedmayr, L., Motameny, S., Nürnberg, G., Nürnberg, P. and Bolz, H.J.
Scientific Reports 7 (1): 1411. 3 May 2017

Disruption of the vacuolar-type H(+)-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes.
Kissing, S., Rudnik, S., Damme, M., Luellmann-Rauch, R., Ichihara, A., Kornak, U., Eskelinen, E.L., Jabs, S., Heeren, J., De Brabander, J.K., Haas, A. and Saftig, P.
Autophagy 13 (4): 670-685. April 2017

High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
Kitada, K., Daub, S., Zhang, Y., Klein, J. D., Nakano, D., Pedchenko, T., Lantier, L., LaRocque, L.M., Marton, A., Neubert, P., Schröder, A., Rakova, N., Jantsch, J., Dikalova, A.E., Dikalov, S.I., Harrison, D.G., Müller, D.N., Nishiyama, A., Rauh, M., Harris, R. C., Luft, F.C., Wassermann, D.H., Sands, J.M. and Titze, J.
Journal of Clinical Investigation 127 (5): 1944-1959. 1 May 2017

Longer-term impact of hemiparetic stroke on skeletal muscle metabolism - a pilot study.
Klaer, J., Mähler, A., Scherbakov, N., Klug, L., von Haehling, S., Boschmann, M. and Doehner, W.
International Journal of Cardiology 230 : 241-247. 1 March 2017

High risk of postpartum relapses in neuromyelitis optica spectrum disorder.
Klawiter, E.C., Bove, R., Elsone, L., Alvarez, E., Borisow, N., Cortez, M., Mateen, F., Mealy, M.A., Sorum, J., Mutch, K., Tobyne, S.M., Ruprecht, K., Buckle, G., Levy, M., Wingerchuk, D., Paul, F., Cross, A.H., Jacobs, A., Chitnis, T. and Weinshenker, B.
Neurology 89 (22): 2238-2244. 28 November 2017

Pole-to-Pole connections: similarities between arctic and antarctic microbiomes and their vulnerability to environmental change.
Kleinteich, J., Hildebrand, F., Bahram, M., Voigt, A.Y., Wood, S.A., Jungblut, A.D., Kuepper, F.C., Quesada, A., Camacho, A., Pearce, D.A., Convey, P., Vincent, W.F., Zarfl, C., Bork, P. and Dietrich, D.R.
Frontiers in Ecology and Evolution 5 : 137. 10 November 2017

Gut microbiota differs between children with inflammatory bowel disease and healthy siblings in taxonomic and functional composition: a metagenomic analysis.
Knoll, R.L., Forslund, K., Kultima, J.R., Meyer, C.U., Kullmer, U., Sunagawa, S., Bork, P. and Gehring, S.
American Journal of Physiology Gastrointestinal and Liver Physiology 312 (4): G327-G339. 1 April 2017

Alkaline poly(ethylene glycol)-based hydrogels for a potential use as bioactive wound dressings.
Koehler, J., Verheyen, L., Hedtrich, S., Brandl, F.P. and Goepferich, A.M.
Journal of Biomedical Materials Research Part A 105 (12): 3360-3368. December 2017

pH-modulating poly(ethylene glycol)/alginate hydrogel dressings for the treatment of chronic wounds.
Koehler, J., Wallmeyer, L., Hedtrich, S., Goepferich, A.M. and Brandl, F.P.
Macromolecular Bioscience 17 (5): 1600369. May 2017

Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits.
Konigorski, S., Yilmaz, Y.E. and Pischon, T.
PLoS ONE 12 (5): e0178504. 31 May 2017

Alloimmune responses of humanized mice to human pluripotent stem cell therapeutics.
Kooreman, N.G., de Almeida, P.E., Stack, J.P., Nelakanti, R.V., Diecke, S., Shao, N.Y., Swijnenburg, R.J., Sanchez-Freire, V., Matsa, E., Liu, C., Connolly, A.J., Hamming, J.F., Quax, P.H.A., Brehm, M.A., Greiner, D.L., Shultz, L.D. and Wu, J.C.
Cell Reports 20 (8): 1978-1990. 22 August 2017

Na(+) deposition in the fibrotic skin of systemic sclerosis patients detected by (23)Na-magnetic resonance imaging.
Kopp, C., Beyer, C., Linz, P., Dahlmann, A., Hammon, M., Jantsch, J., Neubert, P., Rosenhauer, D., Müller, D.N., Cavallaro, A., Eckardt, K.U., Schett, G., Luft, F.C., Uder, M., Distler, J.H.W. and Titze, J.
Rheumatology 56 (4): 556-560. 1 April 2017

Dynamics and heterogeneity of brain damage in multiple sclerosis.
Kotelnikova, E., Kiani, N.A., Abad, E., Martinez-Lapiscina, E.H., Andorra, M., Zubizarreta, I., Pulido-Valdeolivas, I., Pertsovskaya, I., Alexopoulos, L.G., Olsson, T., Martin, R., Paul, F., Tegnér, J., Garcia-Ojalvo, J. and Villoslada, P.
PLoS Computational Biology 13 (10): e1005757. 26 October 2017

Astrocytic calcium waves signal brain injury to neural stem and progenitor cells.
Kraft, A., Jubal, E.R., von Laer, R., Döring, C., Rocha, A., Grebbin, M., Zenke, M., Kettenmann, H., Stroh, A. and Momma, S.
Stem Cell Reports 8 (3): 701-714. 14 March 2017

IKZF1 expression is a prognostic marker in newly diagnosed standard-risk multiple myeloma treated with lenalidomide and intensive chemotherapy: a study of the German Myeloma Study Group (DSMM).
Krönke, J., Kuchenbauer, F., Kull, M., Teleanu, V., Bullinger, L., Bunjes, D., Greiner, A., Kolmus, S., Köpff, S., Schreder, M., Mügge, L.O., Straka, C., Engelhardt, M., Döhner, H., Einsele, H., Bassermann, F., Bargou, R., Knop, S. and Langer, C.
Leukemia 31 (6): 1363-1367. June 2017

Subjective and objective assessment of physical activity in multiple sclerosis and their relation to health-related quality of life.
Krüger, T., Behrens, J.R., Grobelny, A., Otte, K., Mansow-Model, S., Kayser, B., Bellmann-Strobl, J., Brandt, A.U., Paul, F. and Schmitz-Hübsch, T.
BMC Neurology 17 (1): 10. 13 January 2017

Placental-specific overexpression of sFlt-1 alters trophoblast differentiation and nutrient transporter expression in an IUGR mouse model.
Kuehnel, E., Kleff, V., Stojanovska, V., Kaiser, S., Waldschuetz, R., Herse, F., Ploesch, T., Winterhager, E. and Gellhaus, A.
Journal of Cellular Biochemistry 118 (6): 1316-1329. June 2017

Localized irradiation of mouse legs using an image-guided robotic linear accelerator.
Kufeld, M., Escobar, H., Marg, A., Pasemann, D., Budach, V. and Spuler, S.
Annals of Translational Medicine 5 (7): 156. April 2017

S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.
Kumar, A., Dejanovic, B., Hetsch, F., Semtner, M., Fusca, D., Arjune, S., Santamaria-Araujo, J.A., Winkelmann, A., Ayton, S., Bush, A.I., Kloppenburg, P., Meier, J.C., Schwarz, G. and Belaidi, A.A.
Journal of Clinical Investigation 127 (12): 4365-4378. 1 December 2017

The global cardiovascular magnetic resonance registry (GCMR) of the society for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments.
Kwong, R.Y., Petersen, S.E., Schulz-Menger, J., Arai, A.E., Bingham, S.E., Chen, Y., Choi, Y.L., Cury, R.C., Ferreira, V.M., Flamm, S.D., Steel, K., Bandettini, W.P., Martin, E.T., Nallamshetty, L., Neubauer, S., Raman, S.V., Schelbert, E.B., Valeti, U.S., Cao, J.J., Reichek, N., Young, A.A., Fexon, L., Pivovarov, M., Ferrari, V.A. and Simonetti, O.P.
Journal of Cardiovascular Magnetic Resonance 19 (1): 23. 20 January 2017

Mouse cutaneous melanoma induced by mutant BRaf arises from expansion and dedifferentiation of mature pigmented melanocytes.
Köhler, C., Nittner, D., Rambow, F., Radaelli, E., Stanchi, F., Vandamme, N., Baggiolini, A., Sommer, L., Berx, G., van den Oord, J.J., Gerhardt, H., Blanpain, C. and Marine, J.C.
Cell Stem Cell 21 (5): 679-693.e6. 2 November 2017

Prevalence of impaired kidney function in the German elderly: results from the Berlin Aging Study II (BASE-II).
König, M., Gollasch, M., Demuth, I. and Steinhagen-Thiessen, Elisabeth
Gerontology 63 (3): 201-209. April 2017

Tomo-seq identifies SOX9 as a key regulator of cardiac fibrosis during ischemic injury.
Lacraz, G.P.A., Junker, J.P., Gladka, M.M., Molenaar, B., Scholman, K.T., Vigil-Garcia, M., Versteeg, D., de Ruiter, H., Vermunt, M.W., Creyghton, M.P., Huibers, M.M.H., de Jonge, N., van Oudenaarden, A. and van Rooij, E.
Circulation 136 (15): 1396-1409. 10 October 2017

A genomic comparison of putative pathogenicity-related gene families in five members of the Ophiostomatales with different lifestyles.
Lah, L., Löber, U., Hsiang, T. and Hartmann, S.
Fungal Biology 121 (3): 234-252. March 2017

Alzheimer's disease: elevated pigment epithelium-derived factor in the cerebrospinal fluid is mostly of systemic origin.
Lang, V., Zille, M., Infante-Duarte, C., Jarius, S., Jahn, H., Paul, F., Ruprecht, K. and Pina, A.L.
Journal of the Neurological Sciences 375 : 123-128. 15 April 2017

Salt sensitivity of angiogenesis inhibition-induced blood pressure rise: role of interstitial sodium accumulation?
Lankhorst, S., Severs, D., Markó, L., Rakova, N., Titze, J., Müller, D.N., Danser, A.H.J. and van den Meiracker, A.H.
Hypertension 69 (5): 919-926. May 2017

Purification and characterisation of the yeast plasma membrane ATP binding cassette transporter Pdr11p.
Laub, K.R., Marek, M., Stanchev, L.D., Herrera, S.A., Kanashova, T., Bourmaud, A., Dittmar, G. and Guenther Pomorski, T.
PLoS ONE 12 (9): e0184236. 18 September 2017

Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology.
Le Thanh, P., Meinke, P., Korfali, N., Srsen, V., Robson, M.I., Wehnert, M., Schoser, B., Sewry, C.A. and Schirmer, E.C.
Neuromuscular Disorders 27 (4): 338-351. April 2017

Ensembles of lasso screening rules.
Lee, S., Görnitz, N., Xing, E.P., Heckerman, D. and Lippert, C.
IEEE Transactions on Pattern Analysis and Machine Intelligence 40 (12): 2841-2852. 24 November 2017

Circ-ZNF609 is a circular RNA that can be translated and functions in myogenesis.
Legnini, I., Di Timoteo, G., Rossi, F., Morlando, M., Briganti, F., Sthandier, O., Fatica, A., Santini, T., Andronache, A., Wade, M., Laneve, P., Rajewsky, N. and Bozzoni, I.
Molecular Cell 66 (1): 22-37.e9. 6 April 2017

Evidence for heterodimerization and functional interaction of the angiotensin Type 2 receptor and the receptor MAS.
Leonhardt, J., Villela, D.C., Teichmann, A., Münter, L.-M., Mayer, M.C., Mardahl, M., Kirsch, S., Namsolleck, P., Lucht, K., Benz, V., Alenina, N., Daniell, N., Horiuchi, M., Iwai, M., Multhaup, G., Schülein, R., Bader, M., Santos, R.A., Unger, T. and Steckelings, U.M.
Hypertension 69 (6): 1128-1135. June 2017

Cardiac morphofunctional characteristics of transgenic rats with overexpression of the bradykinin B1 receptor in the endothelium.
Levy, R.F., Serra, A.J., Antonio, E.L., dos Santos, L., Bocalini, D.S., Pesquero, J.B., Bader, M., Merino, V.F., de Oliveira, H.A., de Arruda Veiga, E.C., Silva, J.A. and Tucci, P.J.F.
Physiological Research 66 (6): 925-932. 22 September 2017

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.
Liao, C., Ashley, N., Diot, A., Morten, K., Phadwal, K., Williams, A., Fearnley, I., Rosser, L., Lowndes, J., Fratter, C., Ferguson, D.J.P., Vay, L., Quaghebeur, G., Moroni, I., Bianchi, S., Lamperti, C., Downes, S.M., Sitarz, K.S., Flannery, P.J., Carver, J., Dombi, E., East, D., Laura, M., Reilly, M.M., Mortiboys, H., Prevo, R., Campanella, M., Daniels, M.J., Zeviani, M., Yu-Wai-Man, P., Simon, A.K., Votruba, M. and Poulton, J.
Neurology 88 (2): 131-142. 10 January 2017

Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice.
Lim, C.S., Kim, H., Yu, N.K., Kang, S.J., Kim, T.H., Ko, H.G., Lee, J., Yang, J.E., Ryu, H.H., Park, T., Gim, J., Nam, H.J., Baek, S.H., Wegener, S., Schmitz, D., Boeckers, T.M., Lee, M.G., Kim, E., Lee, J.H., Lee, Y.S. and Kaang, B.K.
Neuropharmacology 112 (Part A): 104-112. January 2017

Electrocardiographic assessments and cardiac events after fingolimod first dose - a comprehensive monitoring study.
Limmroth, V., Ziemssen, T., Lang, M., Richter, S., Wagner, B., Haas, J., Schmidt, S., Gerbershagen, K., Lassek, C., Klotz, L., Hoffmann, O., Albert, C., Schuh, K., Baier-Ebert, M., Wendt, G., Schieb, H., Hoyer, S., Dechend, R. and Haverkamp, W.
BMC Neurology 17 (1): 11. 18 January 2017

Fusion of SpCas9 to E.coli Rec A protein enhances CRISPR-Cas9 mediated gene knockout in mammalian cells.
Lin, L., Petersen, T.S., Jensen, K.T., Bolund, L., Kühn, R. and Luo, Y.
Journal of Biotechnology 247 : 42-49. 10 April 2017

Identification of individuals by trait prediction using whole-genome sequencing data.
Lippert, C., Sabatini, R., Maher, M.C., Kang, E.Y., Lee, S., Arikan, O., Harley, A., Bernal, A., Garst, P., Lavrenko, V., Yocum, K., Wong, T., Zhu, M., Yang, W.Y., Chang, C., Lu, T., Lee, C.W.H., Hicks, B., Ramakrishnan, S., Tang, H., Xie, C., Piper, J., Brewerton, S., Turpaz, Y., Telenti, A., Roby, R.K., Och, F.J. and Venter, J.C.
Proceedings of the National Academy of Sciences of the United States of America 114 (38): 10166-10171. 19 September 2017

Downregulation of Plzf gene ameliorates metabolic and cardiac traits in the spontaneously hypertensive rat.
Liška, F., Landa, V., Zidek, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Strnad, H., Trnovská, J., Škop, V., Kazdová, L., Starker, C.G., Voytas, D.F., Izsvák, Z., Mancini, M., Šeda, O., Křen, V. and Pravenec, M.
Hypertension 69 (6): 1084-1091. June 2017

Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma.
Lodrini, M., Sprüssel, A., Astrahantseff, K., Tiburtius, D., Konschak, R., Lode, H.N., Fischer, M., Keilholz, U., Eggert, A. and Deubzer, H.E.
Oncotarget 8 (49): 85234-85251. 17 October 2017

Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders.
Lorenz, C., Lesimple, P., Bukowiecki, R., Zink, A., Inak, G., Mlody, B., Singh, M., Semtner, M., Mah, N., Auré, K., Leong, M., Zabiegalov, O., Lyras, E.M., Pfiffer, V., Fauler, B., Eichhorst, J., Wiesner, B., Huebner, N., Priller, J., Mielke, T., Meierhofer, D., Izsvák, Z., Meier, J.C., Bouillaud, F., Adjaye, J., Schuelke, M., Wanker, E.E., Lombès, A. and Prigione, A.
Cell Stem Cell 20 (5): 659-674.e9. 4 May 2017

Unbiased identification of T cell receptors targeting immunodominant peptide-MHC complexes for T cell receptor immunotherapy.
Lorenz, F.K.M., Ellinger, C., Kieback, E., Wilde, S., Lietz, M., Schendel, D.J. and Uckert, W.
Human Gene Therapy 28 (12): 1158-1168. 1 December 2017

Berlin Wild - and the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch.
Luft, F.C.
Journal of Molecular Medicine 95 (6): 567-570. June 2017

Mesangial renal disease, oxygen sensing, and prolyl hydroxylase.
Luft, F.C.
Journal of Molecular Medicine 95 (3): 235-237. March 2017

Mesenchymal stem cells provide novel insights into ankylosing spondylitis.
Luft, F.C.
Journal of Molecular Medicine 95 (2): 119-121. February 2017

What have we learned from the genetics of hypertension?
Luft, F.C.
Medical Clinics of North America 101 (1): 195-206. January 2017

Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.
Lutter, D., Ullrich, F., Lueck, J.C., Kempa, S. and Jentsch, T.J.
Journal of Cell Science 130 (6): 1122-1133. 15 March 2017

Malnutrition predicts clinical outcome in patients with neuroendocrine neoplasias.
Maasberg, S., Knappe-Drzikova, B., Vonderbeck, D., Jann, H., Weylandt, K.H., Grieser, C., Pascher, A., Schefold, J.C., Pavel, M., Wiedenmann, B., Sturm, A. and Pape, U.F.
Neuroendocrinology 104 (1): 11-25. 2017

A map of human circular RNAs in clinically relevant tissues.
Maass, P.G., Glažar, P., Memczak, S., Dittmar, G., Hollfinger, I., Schreyer, L., Sauer, A.V., Toka, O., Aiuti, A., Luft, F.C. and Rajewsky, N.
Journal of Molecular Medicine 95 (11): 1179-1189. November 2017

Genome-wide identification of regulatory elements in Sertoli cells.
Maatouk, D.M., Natarajan, A., Shibata, Y., Song, L., Crawford, G.E., Ohler, U. and Capel, B.
Development 144 (4): 720-730. 15 February 2017

Transcriptome-wide identification of RNA-binding protein binding sites using photoactivatable-ribonucleoside-enhanced crosslinking immunoprecipitation (PAR-CLIP).
Maatz, H., Kolinski, M., Hubner, N. and Landthaler, M.
Current Protocols in Molecular Biology 118 : 27.6.1-27.6.19. 3 April 2017

Epigenetics and control of RNAs.
Maatz, H., van Heesch, S., Kreuchwig, F., Faber, A., Adami, E., Hubner, N. and Heinig, M.
Methods in Molecular Biology 1488 : 217-237. 2017

Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II.
Maier, C., Schadock, I., Haber, P.K., Wysocki, J., Ye, M., Kanwar, Y., Flask, C.A., Yu, X., Hoit, B.D., Adams, G.N., Schmaier, A.H., Bader, M. and Batlle, D.
Journal of Molecular Medicine 95 (5): 473-486. May 2017

DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.
Mamlouk, S., Childs, L.H., Aust, D., Heim, D., Melching, F., Oliveira, C., Wolf, T., Durek, P., Schumacher, D., Blaeker, H., von Winterfeld, M., Gastl, B., Moehr, K., Menne, A., Zeugner, S., Redmer, T., Lenze, D., Tierling, S., Moebs, M., Weichert, W., Folprecht, G., Blanc, E., Beule, D., Schaefer, R., Morkel, M., Klauschen, F., Leser, U. and Sers, C.
Nature Communications 8 : 14093. 25 January 2017

The technical report on sodium intake and cardiovascular disease in low- and middle-income countries by the joint working group of the World Heart Federation, the European Society of Hypertension and the European Public Health Association.
Mancia, G., Oparil, S., Whelton, P.K., McKee, M., Dominiczak, A., Luft, F.C., AlHabib, K., Lanas, F., Damasceno, A., Prabhakaran, D., La Torre, G., Weber, M., O'Donnell, M., Smith, S.C. and Narula, J.
European Heart Journal 38 (10): 712-719. 7 March 2017

Sparse probit linear mixed model.
Mandt, S., Wenzel, F., Nakajima, S., Cunningham, J., Lippert, C. and Kloft, M.
Machine Learning 106 (9-10): 1621-1642. October 2017

Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.
Marenholz, I., Grosche, S., Kalb, B., Rüschendorf, F., Blümchen, K., Schlags, R., Harandi, N., Price, M., Hansen, G., Seidenberg, J., Röblitz, H., Yürek, S., Tschirner, S., Hong, X., Wang, X., Homuth, G., Schmidt, C.O., Nöthen, M.M., Hübner, N., Niggemann, B., Beyer, K. and Lee, Y.A.
Nature Communications 8 (1): 1056. 20 October 2017

Quantitative proteomic analysis of Parkin substrates in Drosophila neurons.
Martinez, A., Lectez, B., Ramirez, J., Popp, O., Sutherland, J.D., Urbe, S., Dittmar, G., Clague, M.J. and Mayor, U.
Molecular Neurodegeneration 12 (1): 29. 11 April 2017

Genomewide association study of peanut allergy reproduces association with amino acid polymorphisms in HLA-DRB1.
Martino, D.J., Ashley, S., Koplin, J., Ellis, J., Saffery, R., Dharmage, S.C., Gurrin, L., Matheson, M.C., Kalb, B., Marenholz, I., Beyer, K., Lee, Y.A., Hong, X., Wang, X., Vukevic, D., Motyer, A., Leslie, S., Allen, K.J. and Ferreira, M.A.R.
Clinical and Experimental Allergy 47 (2): 217-223. February 2017

Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
Mathivet, T., Bouleti, C., Van Woensel, M., Stanchi, F., Verschuere, T., Phng, L.K., Dejaegher, J., Balcer, M., Matsumoto, K., Georgieva, P.B., Belmans, J., Sciot, R., Stockmann, C., Mazzone, M., De Vleeschouwer, S. and Gerhardt, H.
EMBO Molecular Medicine 9 (12): 1629-1645. 1 December 2017

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Mattei, D., Ivanov, A., Ferrai, C., Jordan, P., Guneykaya, D., Buonfiglioli, A., Schaafsma, W., Przanowski, P., Deuther-Conrad, W., Brust, P., Hesse, S., Patt, M., Sabri, O., Ross, T.L., Eggen, B.J.L., Boddeke, E.W.G.M., Kaminska, B., Beule, D., Pombo, A., Kettenmann, H. and Wolf, S.A.
Translational Psychiatry 7 (5): e1120. 9 May 2017

Cell-cell communication mediated by the CAR subgroup of immunoglobulin cell adhesion molecules in health and disease.
Matthäus, C., Langhorst, H., Schütz, L., Jüttner, R. and Rathjen, F.G.
Molecular and Cellular Neuroscience 81 : 32-40. June 2017

The adenosine generating enzymes CD39/CD73 control microglial processes ramification in the mouse brain.
Matyash, M., Zabiegalov, O., Wendt, S., Matyash, V. and Kettenmann, H.
PLoS ONE 12 (4): e0175012. 4 April 2017

Renal function is independently associated with circulating betatrophin.
Maurer, L., Schwarz, F., Fischer-Rosinsky, A., Schlueter, N., Brachs, S., Moehlig, M., Pfeiffer, A., Mai, K., Spranger, J. and Bobbert, T.
PLoS ONE 12 (3): e0173197. 3 March 2017

Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution.
Mauri, M., Kirchner, M., Aharoni, R., Ciolli Mattioli, C., van den Bruck, D., Gutkovitch, N., Modepalli, V., Selbach, M., Moran, Y. and Chekulaeva, M.
Nucleic Acids Research 45 (2): 938-950. 25 January 2017

Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function.
McDermott-Roe, C., Leleu, M., Rowe, G.C., Palygin, O., Bukowy, J.D., Kuo, J., Rech, M., Hermans-Beijnsberger, S., Schaefer, S., Adami, E., Creemers, E.E., Heinig, M., Schroen, B., Arany, Z., Petretto, E. and Geurts, A.M.
PLoS ONE 12 (2): e0170458. 3 February 2017

Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Melo, A.A., Hegde, B.G., Shah, C., Larsson, E., Isas, J.M., Kunz, S., Lundmark, R., Langen, R. and Daumke, O.
Proceedings of the National Academy of Sciences of the United States of America 114 (22): 5629-5634. 30 May 2017

proGenomes: a resource for consistent functional and taxonomic annotations of prokaryotic genomes.
Mende, D.R., Letunic, I., Huerta-Cepas, J., Li, S.S., Forslund, K., Sunagawa, S. and Bork, P.
Nucleic Acids Research 45 (D1): D529-D534. 4 January 2017

An integrative framework reveals signaling-to-transcription events in toll-like receptor signaling.
Mertins, P., Przybylski, D., Yosef, N., Qiao, J., Clauser, K., Raychowdhury, R., Eisenhaure, T.M., Maritzen, T., Haucke, V., Satoh, T., Akira, S., Carr, S.A., Regev, A., Hacohen, N. and Chevrier, N.
Cell Reports 19 (13): 2853-2866. 27 June 2017

HLA-MA: simple yet powerful matching of samples using HLA typing results.
Messerschmidt, C., Holtgrewe, M. and Beule, D.
Bioinformatics 33 (14): 2241-2242. 15 July 2017

In silico methods for co-transcriptional RNA secondary structure prediction and for investigating alternative RNA structure expression.
Meyer, I.M.
Methods 120 : 3-16. 1 May 2017

Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells.
Middelkamp, S., van Heesch, S., Braat, A.K., de Ligt, J., van Iterson, M., Simonis, M., van Roosmalen, M.J., Kelder, M.J.E., Kruisselbrink, E., Hochstenbach, R., Verbeek, N.E., Ippel, E.F., Adolfs, Y., Pasterkamp, R.J., Kloosterman, W.P., Kuijk, E.W. and Cuppen, E.
Genome Medicine 9 (1): 9. 26 January 2017

Patients with multiple sclerosis demonstrate reduced subbasal corneal nerve fibre density.
Mikolajczak, J., Zimmermann, H., Kheirkhah, A., Kadas, E.M., Oberwahrenbrock, T., Muller, R., Ren, A., Kuchling, J., Dietze, H., Prüss, H., Paul, F., Hamrah, P. and Brandt, A.U.
Multiple Sclerosis Journal 23 (14): 1847-1853. 1 December 2017

Genomic characterization of murine monocytes reveals C/EBPβ transcription factor dependence of Ly6C(-) cells.
Mildner, A., Schönheit, J., Giladi, A., David, E., Lara-Astiaso, D., Lorenzo-Vivas, E., Paul, F., Chappell-Maor, L., Priller, J., Leutz, A., Amit, I. and Jung, S.
Immunity 46 (5): 849-862. 16 May 2017

DDX54 regulates transcriptome dynamics during DNA damage response.
Milek, M., Imami, K., Mukherjee, N., De Bortoli, F., Zinnall, U., Hazapis, O., Trahan, C., Oeffinger, M., Heyd, F., Ohler, U., Selbach, M. and Landthaler, M.
Genome Research 27 (8): 1344-1359. August 2017

Tumor-infiltrating merkel cell polyomavirus-specific T cells are diverse and associated with improved patient survival.
Miller, N.J., Church, C.D., Dong, L., Crispin, D., Fitzgibbon, M.P., Lachance, K., Jing, L., Shinohara, M., Gavvovidis, I., Willimsky, G., McIntosh, M., Blankenstein, T., Koelle, D.M. and Nghiem, P.
Cancer Immunology Research 5 (2): 137-147. February 2017

Bioinformatics analysis of functional associations of PTMs.
Minguez, P. and Bork, P.
Methods in Molecular Biology 1558 (1558): 303-320. 2 February 2017

An entropic gradient structure for lindblad equations and couplings of quantum systems to macroscopic models.
Mittnenzweig, M. and Mielke, A.
Journal of Statistical Physics 167 (2): 205-233. April 2017

Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants.
Mlody, B., Wruck, W., Martins, S., Sperling, K. and Adjaye, J.
Scientific Reports 7 (1): 7516. 8 August 2017

Dysregulation of circulating autoantibodies against VEGF-A, VEGFR-1 and PlGF in preeclampsia - a role in placental and vascular health?
Moe, K., Heidecke, H., Dechend, R. and Staff, A.C.
Pregnancy Hypertension 10 : 83-89. October 2017

One-pot and gram-scale synthesis of biodegradable polyglycerols under ambient conditions: nanocarriers for intradermal drug delivery.
Mohammadifar, E., Zabihi, F., Tu, Z., Hedtrich, S., Nemati Kharat, A., Adeli, M. and Haag, R.
Polymer Chemistry 8 (47): 7375-7383. 21 December 2017

Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy.
Montag, J., Syring, M., Rose, J., Weber, A.L., Ernstberger, P., Mayer, A.K., Becker, E., Keyser, B., Dos Remedios, C., Perrot, A., van der Velden, J., Francino, A., Navarro-Lopez, F., Ho, C.Y., Brenner, B. and Kraft, T.
Journal of Muscle Research and Cell Motility 38 (3-4): 291-302. August 2017

Novel compound heterozygous mutations in TELO2 in a patient with severe expression of You-Hoover-Fong syndrome.
Moosa, S., Altmüller, J., Lyngbye, T., Christensen, R., Li, Y., Nürnberg, P., Yigit, G., Vogel, I. and Wollnik, B.
Molecular Genetics & Genomic Medicine 5 (5): 580-584. September 2017

Confirmation of CAGSSS syndrome as a distinct entity in a Danish patient with a novel homozygous mutation in IARS2.
Moosa, S., Haagerup, A., Gregersen, P.A., Petersen, K.K., Altmüller, J., Thiele, H., Nürnberg, P., Cho, T.J., Kim, O.H., Nishimura, G., Wollnik, B. and Vogel, I.
American Journal of Medical Genetics Part A 173 (4): 1102-1108. April 2017

High aminopeptidase A activity contributes to blood pressure control in ob/ob mice by AT2 receptor-dependent mechanism.
Morais, R.L., Hilzendeger, A.M., Visniauskas, B., Todiras, M., Alenina, N., Mori, M.A., Araújo, R.C., Nakaie, C.R., Chagas, J.R., Carmona, A.., Bader, M. and Pesquero, J.B.
American Journal of Physiology Heart and Circulatory Physiology 312 (3): H437-H445. 1 March 2017

Chaperone-mediated regulation of choline acetyltransferase protein stability and activity by HSC/HSP70, HSP90, and p97/VCP.
Morey, T.M., Winick-Ng, W., Seah, C. and Rylett, R.J.
Frontiers in Molecular Neuroscience 10 : 415. December 2017

Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.
Morgenstern, Y., Das Adhikari, U., Ayyash, M., Elyada, E., Tóth, B., Moor, A., Itzkovitz, S. and Ben-Neriah, Y.
EMBO Journal 36 (20): 3046-3061. 16 October 2017

Congenital deafness is associated with specific somatosensory deficits in adolescents.
Moshourab, R., Bégay, V., Wetzel, C., Walcher, J., Middleton, S., Gross, M. and Lewin, G.R.
Scientific Reports 7 (1): 4251. 26 June 2017

Rodents and humans are able to detect the odour of L-Lactate.
Mosienko, V., Chang, A.J., Alenina, N., Teschemacher, A.G. and Kasparov, S.
PLoS ONE 12 (5): e0178478. 25 May 2017

Developmental origin and maintenance of distinct testicular macrophage populations.
Mossadegh-Keller, N., Gentek, R., Gimenez, G., Bigot, S., Mailfert, S. and Sieweke, M.H.
Journal of Experimental Medicine 214 (10): 2829-2841. 2 October 2017

Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression.
Mudduluru, G., Ilm, K., Fuchs, S. and Stein, U.
Oncotarget 8 (13): 21081-21094. 28 March 2017

Investigation of naturally occurring single-nucleotide variants in human TAAR1.
Muehlhaus, J., Dinter, J., Jyrch, S., Teumer, A., Jacobi, S.F., Homuth, G., Kuehnen, P., Wiegand, S., Grueters, A., Voelzke, H., Raile, K., Kleinau, G., Krude, H. and Biebermann, H.
Frontiers in Pharmacology 8 : 807. 24 November 2017

Integrative classification of human coding and noncoding genes through RNA metabolism profiles.
Mukherjee, N., Calviello, L., Hirsekorn, A., de Pretis, S., Pelizzola, M. and Ohler, U.
Nature Structural & Molecular Biology 24 (1): 86-96. January 2017

Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
Mönke, G., Cristiano, E., Finzel, A., Friedrich, D., Herzel, H., Falcke, M. and Loewer, A.
Scientific Reports 7 : 46571. 18 April 2017

CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis.
Müller, I., Pappritz, K., Savvatis, K., Puhl, K., Dong, F., El-Shafeey, M., Hamdani, N., Hamann, I., Noutsias, M., Infante-Duarte, C., Linke, W.A., Van Linthout, S. and Tschöpe, C.
PLoS ONE 12 (8): e0182643. 11 August 2017

Epidemiological, genetic, and clinical characterization by age of newly diagnosed acute myeloid leukemia based on an academic population-based registry study (AMLSG BiO).
Nagel, G., Weber, D., Fromm, E., Erhardt, S., Lübbert, M., Fiedler, W., Kindler, T., Krauter, J., Brossart, P., Kündgen, A., Salih, H.R., Westermann, J., Wulf, G., Hertenstein, B., Wattad, M., Götze, K., Kraemer, D., Heinicke, T., Girschikofsky, M., Derigs, H.G., Horst, H.A., Rudolph, C., Heuser, M., Göhring, G., Teleanu, V., Bullinger, L., Thol, F., Gaidzik, V.I., Paschka, P., Döhner, K., Ganser, A., Döhner, H. and Schlenk, R.F.
Annals of Hematology 96 (12): 1993-2003. 1 December 2017

microRNA-184 induces a commitment switch to epidermal differentiation.
Nagosa, S., Leesch, F., Putin, D., Bhattacharya, S., Altshuler, A., Serror, L., Amitai-Lange, A., Nasser, W., Aberdam, E., Rouleau, M., Tattikota, S.G., Poy, M.N., Aberdam, D. and Shalom-Feuerstein, R.
Stem Cell Reports 9 (6): 1991-2004. 12 December 2017

Hypoxia induces heart regeneration in adult mice.
Nakada, Y., Canseco, D.C., Thet, S., Abdisalaam, S., Asaithamby, A., Santos, C.X., Shah, A.M., Zhang, Hua, Faber, J.E., Kinter, M.T., Szweda, L.I., Xing, C., Hu, Z., Deberardinis, R.J., Schiattarella, G., Hill, J.A., Oz, O., Lu, Z., Zhang, C.C., Kimura, W. and Sadek, H.A.
Nature 541 (7636): 222-227. 12 January 2017

Identification of the elementary structural units of the DNA damage response.
Natale, F., Rapp, A., Yu, W., Maiser, A., Harz, H., Scholl, A., Grulich, S., Anton, T., Hoerl, D., Chen, W., Durante, M., Taucher-Scholz, G., Leonhardt, H. and Cardoso, M.C.
Nature Communications 8 : 15760. 12 June 2017

The RAD51C exonic splice-site mutations c.404G>C and c.404G>T are associated with familial breast and ovarian cancer.
Neidhardt, G., Becker, A., Hauke, J., Horváth, J., Bogdanova Markov, N., Heilmann-Heimbach, S., Hellebrand, H., Thiele, H., Altmüller, J., Nürnberg, P., Meindl, A., Rhiem, K., Blümcke, B., Wappenschmidt, B., Schmutzler, R.K. and Hahnen, E.
European Journal of Cancer Prevention 26 (2): 165-169. March 2017

Association between loss-of-function mutations within the FANCM gene and early-onset familial breast cancer.
Neidhardt, G., Hauke, J., Ramser, J., Groß, E., Gehrig, A., Müller, C.R., Kahlert, A.K., Hackmann, K., Honisch, E., Niederacher, D., Heilmann-Heimbach, S., Franke, A., Lieb, W., Thiele, H., Altmüller, J., Nürnberg, P., Klaschik, K., Ernst, C., Ditsch, N., Jessen, F., Ramirez, A., Wappenschmidt, B., Engel, C., Rhiem, K., Meindl, A., Schmutzler, R.K. and Hahnen, Eric
JAMA Oncology 3 (9): 1245-1248. 1 September 2017

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.
Nieborowska-Skorska, M., Sullivan, K., Dasgupta, Y., Podszywalow-Bartnicka, P., Hoser, G., Maifrede, S., Martinez, E., Di Marcantonio, D., Bolton-Gillespie, E., Cramer-Morales, K., Lee, J., Li, M., Slupianek, A., Gritsyuk, D., Cerny-Reiterer, S., Seferynska, I., Stoklosa, T., Bullinger, L., Zhao, H., Gorbunova, V., Piwocka, K., Valent, P., Civin, C.I., Muschen, M., Dick, J.E., Wang, J.C., Bhatia, S., Bhatia, R., Eppert, K., Minden, M.D., Sykes, S.M. and Skorski, T.
Journal of Clinical Investigation 127 (6): 2392-2406. 1 June 2017

High field cardiac magnetic resonance imaging: a case for ultrahigh field cardiac magnetic resonance.
Niendorf, T., Schulz-Menger, J., Paul, K., Huelnhagen, T., Ferrari, V.A. and Hodge, R.
Circulation Cardiovascular Imaging 10 (6): e005460. June 2017

High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph.
Nikpey, E., Karlsen, T.V., Rakova, N., Titze, J.M., Tenstad, O. and Wiig, H.
Hypertension 69 (4): 660-668. April 2017

Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies.
Nimptsch, K., Song, M., Aleksandrova, K., Katsoulis, M., Freisling, H., Jenab, M., Gunter, M.J., Tsilidis, K.K., Weiderpass, E., Bueno-De-Mesquita, H.B., Chong, D.Q., Jensen, M.K., Wu, C., Overvad, K., Kühn, T., Barrdahl, M., Melander, O., Jirstrom, K., Peeters, P.H., Sieri, S., Panico, S., Cross, A.J., Riboli, E., Van Guelpen, B., Myte, R., Huerta, J.M., Rodriguez-Barranco, M., Quirós, J.R., Dorronsoro, M., Tjønneland, A., Olsen, A., Travis, R., Boutron-Ruault, M.C., Carbonnel, F., Severi, G., Bonet, C., Palli, D., Janke, J., Lee, Y.A., Boeing, H., Giovannucci, E.L., Ogino, S., Fuchs, C.S., Rimm, E., Wu, K., Chan, A.T. and Pischon, T.
European Journal of Epidemiology 32 (5): 419-430. May 2017

Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features.
Niturad, C.E., Lev, D., Kalscheuer, V.M., Charzewska, A., Schubert, J., Lerman-Sagie, T., Kroes, H.Y., Oegema, R., Traverso, M., Specchio, N., Lassota, M., Chelly, J., Bennett-Back, O., Carmi, N., Koffler-Brill, T., Iacomino, M., Trivisano, M., Capovilla, G., Striano, P., Nawara, M., Rzonca, S., Fischer, U., Bienek, M., Jensen, C., Hu, H., Thiele, H., Altmüller, J., Krause, R., May, P., Becker, F., Balling, R., Biskup, S., Haas, S.A., Nürnberg, P., van Gassen, K.L.I., Lerche, H., Zara, F., Maljevic, S. and Leshinsky-Silver, E.
Brain 140 (11): 2879-2894. 1 November 2017

Participants' decision to enroll in cohort studies with biobanks: quantitative insights from two german studies.
Nobile, H., Borry, P., Pischon, T., Steinbrecher, A., Boeing, H., Vigl, M. and Bergmann, M.M.
Personalized Medicine 14 (6): 477-485. November 2017

FANTOM5 CAGE profiles of human and mouse samples.
Noguchi, S., Arakawa, T., Fukuda, S., Furuno, M., Hasegawa, A., Hori, F., Ishikawa-Kato, S., Kaida, K., Kaiho, A., Kanamori-Katayama, M., Kawashima, T., Kojima, M., Kubosaki, A., Manabe, R.I., Murata, M., Nagao-Sato, S., Nakazato, K., Ninomiya, N., Nishiyori-Sueki, H., Noma, S., Saijyo, E., Saka, A., Sakai, M., Simon, C., Suzuki, N., Tagami, M., Watanabe, S., Yoshida, S., Arner, P., Axton, R.A., Babina, M., Baillie, J.K., Barnett, T.C., Beckhouse, A.G., Blumenthal, A., Bodega, B., Bonetti, A., Briggs, J., Brombacher, F., Carlisle, A.J., Clevers, H.C., Davis, C.A., Detmar, M., Dohi, T., Edge, A.S.B., Edinger, M., Ehrlund, A., Ekwall, K., Endoh, M., Enomoto, H., Eslami, A., Fagiolini, M., Fairbairn, L., Farach-Carson, M.C., Faulkner, G.J., Ferrai, C., Fisher, M.E., Forrester, L.M., Fujita, R., Furusawa, J.I., Geijtenbeek, T.B., Gingeras, T., Goldowitz, D., Guhl, S., Guler, R., Gustincich, S., Ha, T.J., Hamaguchi, M., Hara, M., Hasegawa, Y., Herlyn, M., Heutink, P., Hitchens, K.J., Hume, D.A., Ikawa, T., Ishizu, Y., Kai, C., Kawamoto, H., Kawamura, Y.I., Kempfle, J.S., Kenna, T.J., Kere, J., Khachigian, L.M., Kitamura, T., Klein, S., Klinken, S.P., Knox, A.J., Kojima, S., Koseki, H., Koyasu, S., Lee, W., Lennartsson, A.s, Mackay-Sim, A., Mejhert, N., Mizuno, Y., Morikawa, H., Morimoto, M., Moro, K., Morris, K.J., Motohashi, H., Mummery, C.L., Nakachi, Y., Nakahara, F., Nakamura, T., Nakamura, Y., Nozaki, T., Ogishima, S., Ohkura, N., Ohno, H., Ohshima, M., Okada-Hatakeyama, M., Okazaki, Y., Orlando, V., Ovchinnikov, D.A., Passier, R., Patrikakis, M., Pombo, A., Pradhan-Bhatt, S., Qin, X.Y., Rehli, M., Rizzu, P., Roy, S., Sajantila, A., Sakaguchi, S., Sato, H., Satoh, H., Savvi, S., Saxena, A., Schmidl, C., Schneider, C., Schulze-Tanzil, G.G., Schwegmann, A., Sheng, G., Shin, J.W., Sugiyama, D., Sugiyama, T., Summers, K.M., Takahashi, N., Takai, J., Tanaka, H., Tatsukawa, H., Tomoiu, A., Toyoda, H., van de Wetering, M., van den Berg, L.M., Verardo, R., Vijayan, D., Wells, C.A., Winteringham, L.N., Wolvetang, E., Yamaguchi, Y., Yamamoto, M., Yanagi-Mizuochi, C., Yoneda, M., Yonekura, Y., Zhang, P.G., Zucchelli, S., Abugessaisa, I., Arner, E., Harshbarger, J., Kondo, A., Lassmann, T., Lizio, M., Sahin, S., Sengstag, T., Severin, J., Shimoji, H., Suzuki, M., Suzuki, H., Kawai, J., Kondo, N., Itoh, M., Daub, C.O., Kasukawa, T., Kawaji, H., Carninci, P., Forrest, A.R.R. and Hayashizaki, Y.
Scientific Data 4 : 170112. 29 August 2017

Radiofrequency applicator concepts for simultaneous MR imaging and hyperthermia treatment of glioblastoma multiforme: a 298 MHz(7.0 Tesla) thermal magnetic resonancesimulation study.
Oberacker, E., Kuehne, A., Nadobny, J., Zschaeck, S., Weihrauch, M., Waiczies, H., Ghadjar, P., Wust, P., Niendorf, T. and Winter, L.
Current Directions in Biomedical Engineering 3 (2): 473-477. September 2017

Magnetic resonance safety and compatibility of tantalum markers used in proton beam therapy for intraocular tumors: a 7.0 Tesla study.
Oberacker, E., Paul, K., Huelnhagen, T., Oezerdem, C., Winter, L., Pohlmann, A., Boehmert, L., Stachs, O., Heufelder, J., Weber, A., Rehak, M., Seibel, I. and Niendorf, T.
Magnetic Resonance in Medicine 78 (4): 1533-1546. October 2017

Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation.
Oberheide, K., Puchkov, D. and Jentsch, T.J.
Journal of Biological Chemistry 292 (26): 10845-10854. 30 June 2017

Protein corona formation on colloidal polymeric nanoparticles and polymeric panogels: impact on cellular uptake, toxicity, immunogenicity, and drug release properties.
Obst, K., Yealland, G., Balzus, B., Miceli, E., Dimde, M., Weise, C., Eravci, M., Bodmeier, R., Haag, R., Calderón, M., Charbaji, N. and Hedtrich, S.
Biomacromolecules 18 (6): 1762-1771. 12 June 2017

Microstructural visual system changes in AQP4-antibody-seropositive NMOSD.
Oertel, F.C., Kuchling, J., Zimmermann, H., Chien, C., Schmidt, F., Knier, B., Bellmann-Strobl, J., Korn, T., Scheel, M., Klistorner, A., Ruprecht, K., Paul, F. and Brandt, A.U.
Neurology Neuroimmunology & Neuroinflammation 4 (3): e334. May 2017

Optische Kohaerenztomographie bei Neuromyelitis optica-Spektrum-Erkrankungen [Optical coherence tomography in neuromyelitis optica spectrum disorders].
Oertel, F.C., Zimmermann, H., Brandt, A.U. and Paul, F.
Nervenarzt 88 (12): 1411-1420. December 2017

A diet rich in Omega-3 fatty acids enhances expression of soluble epoxide hydrolase in murine brain.
Ostermann, A.I., Reutzel, M., Hartung, N., Franke, N., Kutzner, L., Schoenfeld, K., Weylandt, K.H., Eckert, G.P. and Schebb, N.H.
Prostaglandins & Other Lipid Mediators 133 : 79-87. November 2017

Modulation of the endogenous omega-3 fatty acid and oxylipin profile in vivo - a comparison of the fat-1 transgenic mouse with C57BL/6 wildtype mice on an omega-3 fatty acid enriched diet.
Ostermann, A.I., Waindok, P., Schmidt, M.J., Chiu, C.Y., Smyl, C., Rohwer, N., Weylandt, K.H. and Schebb, N.H.
PLoS ONE 12 (9): e0184470. 8 September 2017

Protein kinase A regulates C-terminally truncated Ca(V) 1.2 in Xenopus oocytes: roles of N- and C-termini of the α(1C) subunit.
Oz, S., Pankonien, I., Belkacemi, A., Flockerzi, V., Klussmann, E., Haase, H. and Dascal, N.
Journal of Physiology 595 (10): 3181-3202. 15 May 2017

Neuromyelitis optica.
Pache, F., Wildemann, B., Paul, F. and Jarius, S.
Fortschritte der Neurologie Psychiatrie 85 (2): 100-114. February 2017

Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin.
Paeger, L., Karakasilioti, I., Altmüller, J., Frommolt, P., Brüning, J. and Kloppenburg, P.
eLife 6 : e25770. 20 June 2017

Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy.
Pahle, J., Menzel, L., Niesler, N., Kobelt, D., Aumann, J., Rivera, M. and Walther, W.
BMC Cancer 17 (1): 129. 13 February 2017

The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.
Pajtler, K.W., Sadowski, N., Ackermann, S., Althoff, K., Schönbeck, K., Batzke, K., Schäfers, S., Odersky, A., Heukamp, L., Astrahantseff, K., Künkele, A., Deubzer, H.E., Schramm, A., Sprüssel, A., Thor, T., Lindner, S., Eggert, A., Fischer, M. and Schulte, J.H.
Oncotarget 8 (4): 6730-6741. 24 January 2017

Translation of circRNAs.
Pamudurti, N.R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., Shenzis, S., Samson, M., Dittmar, G., Landthaler, M., Chekulaeva, M., Rajewsky, N. and Kadener, S.
Molecular Cell 66 (1): 9-21. 6 April 2017

Scattering compensation by focus scanning holographic aberration probing (F-SHARP).
Papadopoulos, I.N., Jouhanneau, J.S., Poulet, J.F.A. and Judkewitz, B.
Nature Photonics 11 (2): 116-123. February 2017

Single-subject independent component analysis-based intensity normalization in non-quantitative multi-modal structural MRI.
Papazoglou, S., Würfel, J., Paul, F., Brandt, A.U. and Scheel, M.
Human Brain Mapping 38 (7): 3615-3622. July 2017

Does NGAL reduce costs? A cost analysis of urine NGAL (uNGAL) & serum creatinine (sCr) for acute kidney injury (AKI) diagnosis.
Parikh, A., Rizzo, J.A, Canetta, P., Forster, C., Sise, M., Maarouf, O., Singer, E., Elger, A., Elitok, S., Schmidt-Ott, K., Barasch, J. and Nickolas, T.L
PLoS ONE 12 (5): e0178091. 19 May 2017

β1-adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes.
Park, M., Reddy, G.R., Wallukat, G., Xiang, Y.K. and Steinberg, S.F.
Scientific Reports 7 (1): 7890. 11 August 2017

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat.
Park, T.J., Reznick, J., Peterson, B.L., Blass, G., Omerbašić, D., Bennett, N.C., Kuich, P.H.J.L., Zasada, C., Browe, B.M., Hamann, W., Applegate, D.T., Radke, M.H., Kosten, T., Lutermann, H., Gavaghan, V., Eigenbrod, O., Bégay, V., Amoroso, V. G., Govind, V., Minshall, R.D., Smith, E.S.J., Larson, J., Gotthardt, M., Kempa, S. and Lewin, G.R.
Science 356 (6335): 307-311. 21 April 2017

Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitis.
Paterka, M., Voss, J.O., Werr, J., Reuter, E., Franck, S., Leuenberger, T., Herz, J., Radbruch, H., Bopp, T., Siffrin, V. and Zipp, F.
Journal of Autoimmunity 76 : 108-114. January 2017

Kognitive Stoerungen bei Multipler Sklerose und anderen autoimmunen Erkrankungen des zentralen Nervensystems [Cognitive dysfunction in multiple sclerosis and other autoimmune disorders in central nervous system].
Paul, F.
Journal fuer Neurologie Neurochirurgie und Psychiatrie 18 (1): 4-10. 2017

Quantitative GTPase affinity purification identifies Rho family protein interaction partners.
Paul, F., Zauber, H., von Berg, L., Rocks, O., Daumke, O. and Selbach, M.
Molecular & Cellular Proteomics 16 (1): 73-85. 1 January 2017

Functional connectivity of large-scale brain networks in patients with anti-NMDA receptor encephalitis: an observational study.
Peer, M., Prüss, H., Ben-Dayan, I., Paul, F., Arzy, S. and Finke, C.
Lancet Psychiatry 4 (10): 768-774. October 2017

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Pei, W., Feyerabend, T.B., Rössler, J., Wang, X., Postrach, D., Busch, K., Rode, I., Klapproth, K., Dietlein, N., Quedenau, C., Chen, W., Sauer, S., Wolf, S., Höfer, T. and Rodewald, H.Re.
Nature 548 (7668): 456-460. 24 August 2017

The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice.
Pelz, L., Purfürst, B. and Rathjen, F.G.
Journal of Biological Chemistry 292 (52): 21490-21503. 29 December 2017

Tall height and obesity are associated with an increased risk of aggressive prostate cancer: results from the EPIC cohort study.
Perez-Cornago, A., Appleby, P.N., Pischon, T., Tsilidis, K.K., Tjønneland, A., Olsen, A., Overvad, K., Kaaks, R., Kühn, T., Boeing, H., Steffen, A., Trichopoulou, A., Lagiou, P., Kritikou, M., Krogh, V., Palli, D., Sacerdote, C., Tumino, R., Bueno-de-Mesquita, H.B., Agudo, A., Larrañaga, N., Molina-Portillo, E., Barricarte, A., Chirlaque, M.D., Quirós, J.R., Stattin, P., Häggström, C., Wareham, N., Khaw, K.T., Schmidt, J.A., Gunter, M., Freisling, H., Aune, D., Ward, H., Riboli, Elio, Key, T.J. and Travis, R.C.
BMC Medicine 15 : 115. 13 July 2017

Pontine tegmental cap dysplasia in an extremely preterm infant and review of the literature.
Picker-Minh, S., Hartenstein, S., Proquitte, H., Froehler, S., Raile, V., Kraemer, N., Apeshiotis, S., Leipoldt, M., Kalache, K.D., Morris-Rosendahl, D., Boltshauser, E., Chen, W. and Kaindl, A.M.
Journal of Child Neurology 32 (3): 334-340. March 2017

JACUSA: site-specific identification of RNA editing events from replicate sequencing data.
Piechotta, M., Wyler, E., Ohler, U., Landthaler, M. and Dieterich, C.
BMC Bioinformatics 18 (1): 7. 3 January 2017

Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Pieper, K., Tan, J., Piccoli, L., Foglierini, M., Barbieri, S., Chen, Y., Silacci-Fregni, C., Wolf, T., Jarrossay, D., Anderle, M., Abdi, A., Ndungu, F.M., Doumbo, O.K., Traore, B., Tran, T.M., Jongo, S., Zenklusen, I., Crompton, P.D., Daubenberger, C., Bull, P.C., Sallusto, F. and Lanzavecchia, A.
Nature 548 (7669): 597-601. 31 August 2017

Stratum corneum targeting by dendritic core-multishell-nanocarriers in a mouse model of psoriasis.
Pischon, H., Radbruch, M., Ostrowski, A., Volz, P., Gerecke, C., Unbehauen, M., Hönzke, S., Hedtrich, S., Fluhr, J.W., Haag, R., Kleuser, B., Alexiev, U., Gruber, A.D. and Mundhenk, L.
Nanomedicine: Nanotechnology, Biology and Medicine 13 (1): 317-327. January 2017

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.
Piwecka, M., Glažar, P., Hernandez-Miranda, L.R., Memczak, S., Wolf, S.A., Rybak-Wolf, A., Filipchyk, A., Klironomos, F., Cerda Jara, C.A., Fenske, P., Trimbuch, T., Zywitza, V., Plass, M., Schreyer, L., Ayoub, S., Kocks, C., Kühn, R., Rosenmund, C., Birchmeier, C. and Rajewsky, N.
Science 357 (6357): eaam8526. 22 September 2017

Experimental MRI monitoring of renal blood volume fraction variations en route to renal magnetic resonance oximetry.
Pohlmann, A., Cantow, K., Huelnhagen, T., Grosenick, D., dos Santos Periquito, J., Boehmert, L., Gladytz, T., Waiczies, S., Flemming, B., Seeliger, E. and Niendorf, T.
Tomography 3 (4): 188-200. December 2017

The chronically inflamed central nervous system provides niches for long-lived plasma cells.
Pollok, K., Mothes, R., Ulbricht, C., Liebheit, A., Gerken, J.D., Uhlmann, S., Paul, F., Niesner, R., Radbruch, H. and Hauser, A.E.
Acta Neuropathologica Communications 5 (1): 88. 25 November 2017

Dense and accurate whole-chromosome haplotyping of individual genomes.
Porubsky, D., Garg, S., Sanders, A.D., Korbel, J.O., Guryev, V., Lansdorp, P.M. and Marschall, T.
Nature Communications 8 (1): 1293. 3 November 2017

Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.
Pose-Utrilla, J., García-Guerra, L., Del Puerto, A., Martin, A., Jurado-Arjona, J., De León-Reyes, N.S., Gamir-Morralla, A., Sebastián-Serrano, A., García-Gallo, M., Kremer, L., Fielitz, J., Ireson, C., Pérez-Álvarez, M.J., Ferrer, I., Hernández, F., Ávila, J., Lasa, M., Campanero, M.R. and Iglesias, T.
Nature Communications 8 (1): 2275. 22 December 2017

Caloric restriction in older adults - differential effects of weight loss and reduced weight on brain structure and function.
Prehn, K., Jumpertz von Schwartzenberg, R., Mai, K., Zeitz, U., Witte, A.V., Hampel, D., Szela, A.M., Fabian, S., Grittner, U., Spranger, J. and Floeel, A.
Cerebral Cortex 27 (3): 1765-1778. 1 March 2017

IFNα-mediated remodeling of endothelial cells in the bone marrow niche.
Prendergast, Á.M., Kuck, A., van Essen, M., Haas, S., Blaszkiewicz, S. and Essers, M.A.G.
Haematologica 102 (3): 445-453. March 2017

Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-α in a gestational age-dependent manner.
Prokesch, A., Blaschitz, A., Bauer, T., Moser, G., Hiden, U., Zadora, J., Dechend, R., Herse, F. and Gauster, M.
Histochemistry and Cell Biology 147 (6): 695-705. June 2017

Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia.
Qu, Y., Siggens, L., Cordeddu, L., Gaidzik, V.I., Karlsson, K., Bullinger, L., Döhner, K., Ekwall, K., Lehmann, S. and Lennartsson, A.
Blood 129 (7): e13-e25. 16 February 2017

Different inhibitory potencies of oseltamivir carboxylate, zanamivir, and several tannins on bacterial and viral neuraminidases as assessed in a cell-free fluorescence-based enzyme inhibition assay.
Quosdorf, S., Schuetz, A. and Kolodziej, H.
Molecules 22 (11): 1989. 17 November 2017

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.
Radhakrishnan, H., Ilm, K., Walther, W., Shirasawa, S., Sasazuki, T., Daniel, P.T., Gillissen, B. and Stein, U.
Cancer Letters 403 : 231-245. 10 September 2017

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Increased salt consumption induces body water conservation and decreases fluid intake.
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Mutations in γ-secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa.
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Nature Neuroscience 20 (8): 1096-1103. August 2017

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.
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The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown.
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Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.
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Nature Genetics 49 (4): 537-549. April 2017

Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner.
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Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells.
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