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Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Abbosh, C., Frankell, A.M., Harrison, T., Kisistok, J., Garnett, A., Johnson, L., Veeriah, S., Moreau, M., Chesh, A., Chaunzwa, T.L., Weiss, J., Schroeder, M.R., Ward, S., Grigoriadis, K., Shahpurwalla, A., Litchfield, K., Puttick, C., Biswas, D., Karasaki, T., Black, J.R.M., Martínez-Ruiz, C., Bakir, M.A.l., Pich, O., Watkins, T.B.K., Lim, E.L., Huebner, A., Moore, D.A., Godin-Heymann, N., L'Hernault, A., Bye, H., Odell, A., Roberts, P., Gomes, F., Patel, A.J., Manzano, E., Hiley, C.T., Carey, N., Riley, J., Cook, D.E., Hodgson, D., Stetson, D., Barrett, J.C., Kortlever, R.M., Evan, G.I., Hackshaw, A., Daber, R.D., Shaw, J.A., Aerts, H.J.W.L., Licon, A., Stahl, J., Jamal-Hanjani, M., Birkbak, N.J., McGranahan, N. and Swanton, C.
Nature 616
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20 April 2023
Neurofilament light chain elevation and disability progression in multiple sclerosis.
Abdelhak, A., Benkert, P., Schaedelin, S., Boscardin, W.J., Cordano, C., Oechtering, J., Ananth, K., Granziera, C., Melie-Garcia, L., Montes, S.C., Beaudry-Richard, A., Achtnichts, L., Oertel, F.C., Lalive, P.H., Leppert, D., Müller, S., Henry, R.G., Pot, C., Matthias, A., Salmen, A., Oksenberg, J.R., Disanto, G., Zecca, C., D’Souza, M., Du Pasquier, R., Bridel, C., Gobbi, C., Kappos, L., Hauser, S.L., Cree, B.A.C., Kuhle, J. and Green, A.J.
JAMA Neurology 80
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December 2023
Safety and discontinuation rate of dimethyl fumarate (Zadiva®) in patients with multiple sclerosis: an observational retrospective study.
Abolfazli, R., Sahraian, M.A., Tayebi, A., Kafi, H. and Samadzadeh, S.
Journal of Clinical Medicine 12
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27 July 2023
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Abualrous, E.T., Stolzenberg, S., Sticht, J., Wieczorek, M., Roske, Y., Günther, M., Dähn, S., Boesen, B.B., Calvo, M.M., Biese, C., Kuppler, F., Medina-García, Á., Álvaro-Benito, M., Höfer, T., Noé, F. and Freund, C.
Nature Chemical Biology 19
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October 2023
An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor.
Aguirre, T., Hostachy, S., Dornan, G.L., Neuenschwander, M., Seyffarth, C., Haucke, V., Schütz, A., von Kries, J.P. and Fiedler, D.
eLife 21
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16 October 2023
The interleukin-11 receptor variant p.W307R results in craniosynostosis in humans.
Ahmad, I., Lokau, J., Kespohl, B., Malik, N.A., Baig, S.M., Hartig, R., Behme, D., Schwab, R., Altmüller, J., Jameel, M., Mucha, S., Thiele, H., Tariq, M., Nürnberg, P., Erdmann, J. and Garbers, C.
Scientific Reports 13
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18 August 2023
The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions.
Ahmed, S.M., Ragunathan, P., Shin, J., Peter, S., Kleissle, S., Neuenschwander, M., Schäfer, R., von Kries, J.P., Grüber, G. and Dröge, P.
FEBS Letters 597
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August 2023
Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in neuromyelitis optica spectrum disorder.
Aktas, O., Hartung, H.P., Smith, M.A., Rees, W.A., Fujihara, K., Paul, F., Marignier, R., Bennett, J.L., Kim, H.J., Weinshenker, B.G., Pittock, S.J., Wingerchuk, D.M., Cutter, G., She, D., Gunsior, M., Cimbora, D., Katz, E. and Cree, B.A.
Journal of Neurology Neurosurgery and Psychiatry 94
(9): 757-768.
September 2023
The evolution of non-small cell lung cancer metastases in TRACERx.
Al Bakir, M., Huebner, A., Martínez-Ruiz, C., Grigoriadis, K., Watkins, T.B.K., Pich, O., Moore, D.A., Veeriah, S., Ward, S., Laycock, J., Johnson, D., Rowan, A., Razaq, M., Akther, M., Naceur-Lombardelli, C., Prymas, P., Toncheva, A., Hessey, S., Dietzen, M., Colliver, E., Frankell, A.M., Bunkum, A., Lim, E.L., Karasaki, T., Abbosh, C., Hiley, C.T., Hill, M.S., Cook, D.E., Wilson, G.A., Salgado, R., Nye, E., Stone, R.K., Fennell, D.A., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Summers, Y., Lindsay, C.R., Blackhall, F.H., Cave, J., Blyth, K.G., Nair, A., Ahmed, A., Taylor, M.N., Procter, A.J., Falzon, M., Lawrence, D., Navani, N., Thakrar, R.M., Janes, S.M., Papadatos-Pastos, D., Forster, M.D., Lee, S.M., Ahmad, T., Quezada, S.A., Peggs, K.S., Van Loo, P., Dive, C., Hackshaw, A., Birkbak, N.J., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N. and Swanton, C.
Nature 616
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April 2023
Body composition and lung cancer-associated cachexia in TRACERx.
Al-Sawaf, O., Weiss, J., Skrzypski, M., Lam, J.M., Karasaki, T., Zambrana, F., Kidd, A.C., Frankell, A.M., Watkins, T.B.K., Martínez-Ruiz, C., Puttick, C., Black, J.R.M., Huebner, A., Bakir, M.A., Sokač, M., Collins, S., Veeriah, S., Magno, N., Naceur-Lombardelli, C., Prymas, P., Toncheva, A., Ward, S., Jayanth, N., Salgado, R., Bridge, C.P., Christiani, D.C., Mak, R.H., Bay, C., Rosenthal, M., Sattar, N., Welsh, P., Liu, Y., Perrimon, N., Popuri, K., Beg, M.F., McGranahan, N., Hackshaw, A., Breen, D.M., O'Rahilly, S., Birkbak, N.J., Aerts, H.J.W.L., Jamal-Hanjani, M. and Swanton, C.
Nature Medicine 29
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April 2023
Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Alcaniz, J., Winkler, L., Dahlmann, M., Becker, M., Orthmann, A., Haybaeck, J., Krassnig, S., Skofler, C., Kratzsch, T., Kuhn, S.A., Jödicke, A., Linnebacher, M., Fichtner, I., Walther, W. and Hoffmann, J.
Frontiers in Oncology 13
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11 April 2023
Sites of transcription initiation drive mRNA isoform selection.
Alfonso-Gonzalez, C., Legnini, I., Holec, S., Arrigoni, L., Ozbulut, H.C., Mateos, F., Koppstein, D., Rybak-Wolf, A., Bönisch, U., Rajewsky, N. and Hilgers, V.
Cell 186
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25 May 2023
Rapid nuclear deadenylation of mammalian messenger RNA.
Alles, J., Legnini, I., Pacelli, M. and Rajewsky, N.
iScience 26
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20 January 2023
Constitutive depletion of brain serotonin differentially affects rats’ social and cognitive abilities.
Alonso, L., Peeva, P., Stasko, S., Bader, M., Alenina, N., Winter, Y. and Rivalan, M.
iScience 26
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17 February 2023
Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Alteen, M.G., Deme, J.C., Alvarez, C.P., Loppnau, P., Hutchinson, A., Seitova, A., Chandrasekaran, R., Silva Ramos, E., Secker, C., Alqazzaz, M., Wanker, E.E., Lea, S.M., Arrowsmith, C.H. and Harding, R.J.
Structure 31
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7 September 2023
Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain.
Alves-Silva, T., Húngaro, T.G.R., Freitas-Lima, L.C., de Melo Arthur, G., Arruda, A.C., Santos, R.B., Oyama, L.M., Mori, M.A.S., Bader, M. and Araujo, R.C.
iScience 26
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15 December 2023
On multistability and constitutive relations of cell motion on Fibronectin lanes.
Amiri, B., Heyn, J.C.J., Schreiber, C., Rädler, J.O. and Falcke, M.
Biophysical Journal 122
(5): 753-766.
7 March 2023
Multilevel comparison of deep learning models for function quantification in cardiovascular magnetic resonance: on the redundancy of architectural variations.
Ammann, C., Hadler, T., Gröschel, J., Kolbitsch, C. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 10
: 1118499.
18 April 2023
Development and systematic evaluation of decellularization protocols in different application models for diaphragmatic tissue engineering.
Andreas, M.N., Boehm, A.K., Tang, P., Moosburner, S., Klein, O., Daneshgar, A., Gaßner, J.M.G.V., Raschzok, N., Haderer, L., Wulsten, D., Rückert, J.C., Spuler, S., Pratschke, J., Sauer, I.M. and Hillebrandt, K.H.
Biomaterials Advances 153
: 213493.
October 2023
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide.
Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S.K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J.E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M.T., Hoyles, L., Alves, R., Helft, G., Isnard, R., Køber, L., Coelho, L.P., Rouault, C., Gauguier, D., Gøtze, J.P., Prifti, E., Froguel, P., Zucker, J.D., Bäckhed, F., Vestergaard, H., Hansen, T., Oppert, J.M., Blüher, M., Nielsen, J., Raes, J., Bork, P., Yaqoob, M.M., Stumvoll, M., Pedersen, O., Ehrlich, S.D., Clément, K. and Dumas, M.E.
Nature Communications 14
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20 September 2023
Patient-reported ability to walk 4 m and to wash: New clinical endpoints and predictors of survival in patients with pre-terminal cancer.
Anker, M.S., Lena, A., Roeland, E.J., Porthun, J., Schmitz, S., Hadzibegovic, S., Sikorski, P., Wilkenshoff, U., Fröhlich, A.K., Ramer, L.V., Rose, M., Eucker, J., Rassaf, T., Totzeck, M., Lehmann, L.H., von Haehling, S., Coats, A.J.S., Friede, T., Butler, J., Anker, S.D., Riess, H., Landmesser, U., Bullinger, L., Keller, U. and Ahn, J.
Journal of Cachexia Sarcopenia and Muscle 14
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August 2023
Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire.
Anker, M.S., Potthoff, S.K., Lena, A., Porthun, J., Hadzibegovic, S., Evertz, R., Denecke, C., Fröhlich, A.K., Sonntag, F., Regitz-Zagrosek, V., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Spertus, J.A., Anker, S.D., Karakas, M., Bullinger, L., Keller, U., Landmesser, U., Butler, J. and von Haehling, S.
European Journal of Heart Failure 25
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September 2023
Interferon-γ drives macrophage reprogramming, cerebrovascular remodeling, and cognitive dysfunction in a zebrafish and a mouse model of ion imbalance and pressure overload.
Apaydin, D.C., Zakarauskas-Seth, B.I., Carnevale, L., Apaydin, O., Perrotta, M., Carnevale, R., Kotini, M.P., Kotlar-Goldaper, I., Belting, H.G., Carnevale, D., Filosa, A. and Sawamiphak, S.
Cardiovascular research 119
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May 2023
Alpha-1 adrenergic signaling drives cardiac regeneration via extracellular matrix remodeling transcriptional program in zebrafish macrophages.
Apaydin, O., Altaikyzy, A., Filosa, A. and Sawamiphak, S.
Developmental Cell 58
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20 November 2023
The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Appel, L.M., Franke, V., Benedum, J., Grishkovskaya, I., Strobl, X., Polyansky, A., Ammann, G., Platzer, S., Neudolt, A., Wunder, A., Walch, L., Kaiser, S., Zagrovic, B., Djinovic-Carugo, K., Akalin, A. and Slade, D.
Nature Communications 14
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11 January 2023
Stress perfusion cardiac magnetic resonance vs SPECT imaging for detection of coronary artery disease.
Arai, A.E., Schulz-Menger, J., Shah, D.J., Han, Y., Bandettini, W.P., Abraham, A., Woodard, P.K., Selvanayagam, J.B., Hamilton-Craig, C., Tan, R.S., Carr, J., Teo, L., Kramer, C.M., Wintersperger, B.J., Harisinghani, M.G., Flamm, S.D., Friedrich, M.G., Klem, I., Raman, S.V., Haverstock, D., Liu, Z., Brueggenwerth, G., Santiuste, M., Berman, D.S. and Pennell, D.J.
Journal of the American College of Cardiology 82
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7 November 2023
Linee guida ESC 2023 per il trattamento delle cardiomiopatie [2023 ESC Guidelines for the management of cardiomyopathies].
Arbelo, E., Protonotarios, A., Gimeno, J.R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C.R., Biagini, E., Blom, N.A., de Boer, R.A., De Winter, T., Elliott, P.M., Flather, M., Garcia-Pavia, P., Haugaa, K.H., Ingles, J., Jurcut, R.O., Klaassen, S., Limongelli, G., Loeys, B., Mogensen, J., Olivotto, I., Pantazis, A., Sharma, S., Van Tintelen, J.P., Ware, J.S. and Kaski, J.P.
Giornale Italiano di Cardiologia 24
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November 2023
2023 ESC Guidelines for the management of cardiomyopathies: developed by the task force on the management of cardiomyopathies of the European Society of Cardiology (ESC).
Arbelo, E., Protonotarios, A., Gimeno, J.R., Arbustini, E., Barriales-Villa, R., Basso, C., Bezzina, C.R., Biagini, E., Blom, N.A., de Boer, R.A., De Winter, T., Elliott, P.M., Flather, M., Garcia-Pavia, P., Haugaa, K.H., Ingles, J., Jurcut, R.O., Klaassen, S., Limongelli, G., Loeys, B., Mogensen, J., Olivotto, I., Pantazis, A., Sharma, S., Van Tintelen, J.P., Ware, J.S. and Kaski, J.P.
European Heart Journal 44
(37): 3503-3626.
1 October 2023
Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Arends, C.M., Liman, T.G., Strzelecka, P.M., Kufner, A., Löwe, P., Huo, S., Stein, C.M., Piper, S.K., Tilgner, M., Sperber, P.S., Dimitriou, S., Heuschmann, P., Hablesreiter, R., Harms, C., Bullinger, L., Weber, J.E., Endres, M. and Damm, F.
Blood 141
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16 February 2023
Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles.
Aschman, T., Wyler, E., Baum, O., Hentschel, A., Rust, R., Legler, F., Preusse, C., Meyer-Arndt, L., Büttnerova, I., Förster, A., Cengiz, D., Teixeira Alves, L.G., Schneider, J., Kedor, C., Bellmann-Strobl, J., Sanchin, A., Goebel, H.H., Landthaler, M., Corman, V., Roos, A., Heppner, F.L., Radbruch, H., Paul, F., Scheibenbogen, C., Dengler, N.F. and Stenzel, W.
Acta Neuropathologica Communications 11
(1): 193.
8 December 2023
The Acute Optic Neuritis Network (ACON): study protocol of a non-interventional prospective multicenter study on diagnosis and treatment of acute optic neuritis.
Asseyer, S., Asgari, N., Bennett, J., Bialer, O., Blanco, Y., Bosello, F., Camos-Carreras, A., Carnero Contentti, E., Carta, S., Chen, J., Chien, C., Chomba, M., Dale, R.C., Dalmau, J., Feldmann, K., Flanagan, E.P., Froment Tilikete, C., Garcia-Alfonso, C., Havla, J., Hellmann, M., Kim, H.J., Klyscz, P., Konietschke, F., La Morgia, C., Lana-Peixoto, M., Leite, M.I., Levin, N., Levy, M., Llufriu, S., Lopez, P., Lotan, I., Lugaresi, A., Marignier, R., Mariotto, S., Mollan, S.P., Ocampo, C., Oertel, F.C., Olszewska, M., Palace, J., Pandit, L., Peralta Uribe, J.L., Pittock, S., Ramanathan, S., Rattanathamsakul, N., Saiz, A., Samadzadeh, S., Sanchez-Dalmau, B., Saylor, D., Scheel, M., Schmitz-Hübsch, T., Shifa, J., Siritho, S., Sperber, P.S., Subramanian, P.S., Tiosano, A., Vaknin-Dembinsky, A., Mejia Vergara, A.J., Wilf-Yarkoni, A., Zarco, L.A., Zimmermann, H.G., Paul, F. and Stiebel-Kalish, H.
Frontiers in Neurology 14
: 1102353.
24 February 2023
Expanding the spectrum of EEF1D neurodevelopmental disorders: biallelic variants in the guanine exchange domain.
Averdunk, L., Al-Thihli, K., Surowy, H., Lüdecke, H.J., Drechsler, M., Yigit, G., Smorag, L., Hallak, B.A., Li, Y., Altmüller, J., Guthoff, T., Wallot, M., Nürnberg, P., Wollnik, B., Abou Jamra, R., Al-Maawali, A. and Wieczorek, D.
Clinical Genetics 103
(4): 484-491.
April 2023
Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G., Bartolomaeus, H., Rauch, A., Chen, C.Y., N'Diaye, G., Löber, U., Bartolomaeus, T.U.P., Fritsche-Guenther, R., Rodrigues, A.F., Yarritu, A., Zhong, C., Fei, L., Tsvetkov, D., Todiras, M., Park, J.K., Markó, L., Maifeld, A., Patzak, A., Bader, M., Kempa, S., Kirwan, J.A., Forslund, S.K., Müller, D.N. and Wilck, N.
Cardiovascular Research 119
(6): 1441-1452.
May 2023
Immunoglobulin A antibodies against myelin oligodendrocyte glycoprotein in a subgroup of patients with central nervous system demyelination.
Ayroza Galvão Ribeiro Gomes, A.B., Kulsvehagen, L., Lipps, P., Cagol, A., Cerdá-Fuertes, N., Neziraj, T., Flammer, J., Lerner, J., Lecourt, A.C., de Oliveira S Siebenborn, N., Cortese, R., Schaedelin, S., Andreoli Schoeps, V., de Moura Brasil Matos, A., Trombini Mendes, N., Dos Reis Pereira, C., Ribeiro Monteiro, M.L., Dos Apóstolos-Pereira, S.L., Schindler, P., Chien, C., Schwake, C., Schneider, R., Pakeerathan, T., Aktas, O., Fischer, U., Mehling, M., Derfuss, T., Kappos, L., Ayzenberg, I., Ringelstein, M., Paul, F., Callegaro, D., Kuhle, J., Papadopoulou, A., Granziera, C. and Pröbstel, A.K.
JAMA Neurology 80
(9): 989-995.
September 2023
GPER activation attenuates cardiac dysfunction by upregulating the SIRT1/3-AMPK-UCP2 pathway in postmenopausal diabetic rats.
Azizian, H., Farhadi, Z., Bader, M., Ghalenoei, J.A., Ghafari, M.A. and Mahmoodzadeh, S.
PLoS ONE 18
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22 December 2023
Immune phenotypes and checkpoint molecule expression of clonally expanded lymph node-infiltrating T cells in classical Hodgkin lymphoma.
Ballhausen, A., Ben Hamza, A., Welters, C., Dietze, K., Bullinger, L., Rahn, H.P., Hartmann, S., Hansmann, M.L. and Hansmann, L.
Cancer Immunology Immunotherapy 72
(2): 515-521.
February 2023
Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR.
Balyschew, N., Yushkevich, A., Mikirtumov, V., Sanchez, R.M., Sprink, T. and Kudryashev, M.
Nature Communications 14
(1): 6543.
17 October 2023
Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria.
Banwell, B., Bennett, J.L., Marignier, R., Kim, H.J., Brilot, F., Flanagan, E.P., Ramanathan, S., Waters, P., Tenembaum, S., Graves, J.S., Chitnis, T., Brandt, A.U., Hemingway, C., Neuteboom, R., Pandit, L., Reindl, M., Saiz, A., Sato, D.K., Rostasy, K., Paul, F., Pittock, S.J., Fujihara, K. and Palace, J.
Lancet Neurology 22
(3): 268-282.
March 2023
Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C.
Beagrie, R.A., Thieme, C.J., Annunziatella, C., Baugher, C., Zhang, Y., Schueler, M., Kukalev, A., Kempfer, R., Chiariello, A.M., Bianco, S., Li, Y., Davis, T., Scialdone, A., Welch, L.R., Nicodemi, M. and Pombo, A.
Nature Methods 20
(7): 1037-1047.
July 2023
Impact of genetic deletion of MrgD or Mas receptors in depressive-like behaviour in mice.
Becari, L., Fonseca, M.L.A., Gonçalves, S.C.A, Bader, M., Santos, R.A.S., Campagnole-Santos, M.J. and Kangussu, L.M.
Acta Neuropsychiatrica 35
(1): 27-34.
February 2023
Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal neoplasia.
Bech, J.M., Terkelsen, T., Bartels, A.S., Coscia, F., Doll, S., Zhao, S., Zhang, Z., Brünner, N., Lindebjerg, J., Madsen, G.I., Fang, X., Mann, M. and Moreira, J.M.A.
Gastroenterology 165
(1): 121-132.e5.
July 2023
Current practice of blood pressure measurement in Germany: a nationwide questionnaire-based survey in medical practices.
Beger, C., Mayerböck, A., Klein, K., Karg, T., Schmidt-Ott, K.M., Randerath, O. and Limbourg, F.P.
Blood Pressure 32
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2023
Establishment and thorough characterization of xenograft (PDX) models derived from patients with pancreatic cancer for molecular analyses and chemosensitivity testing.
Behrens, D., Pfohl, U., Conrad, T., Becker, M., Brzezicha, B., Büttner, B., Wagner, S., Hallas, C., Lawlor, R., Khazak, V., Linnebacher, M., Wartmann, T., Fichtner, I., Hoffmann, J., Dahlmann, M. and Walther, W.
Cancers 15
(24): 5753.
8 December 2023
Leveraging large language models for decision support in personalized oncology.
Benary, M., Wang, X.D., Schmidt, M., Soll, D., Hilfenhaus, G., Nassir, M., Sigler, C., Knödler, M., Keller, U., Beule, D., Keilholz, U., Leser, U. and Rieke, D.T.
JAMA Network Open 6
(11): e2343689.
November 2023
The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation.
Benedum, J., Franke, V., Appel, L.M., Walch, L., Bruno, M., Schneeweiss, R., Gruber, J., Oberndorfer, H., Frank, E., Strobl, X., Polyansky, A., Zagrovic, B., Akalin, A. and Slade, D.
Nature Communications 14
(1): 7912.
30 November 2023
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia.
Beneyto-Calabuig, S., Merbach, A.K., Kniffka, J.A., Antes, M., Szu-Tu, C., Rohde, C., Waclawiczek, A., Stelmach, P., Gräßle, S., Pervan, P., Janssen, M., Landry, J.J.M., Benes, V., Jauch, A., Brough, M., Bauer, M., Besenbeck, B., Felden, J., Bäumer, S., Hundemer, M., Sauer, T., Pabst, C., Wickenhauser, C., Angenendt, L., Schliemann, C., Trumpp, A., Haas, S., Scherer, M., Raffel, S., Müller-Tidow, C. and Velten, L.
Cell Stem Cell 30
(5): 706-721.
4 May 2023
Aberrant adenosine triphosphate release and impairment of P2Y2-Mediated signaling in sarcoglycanopathies.
Benzi, A., Baratto, S., Astigiano, C., Sturla, L., Panicucci, C., Mamchaoui, K., Raffaghello, L., Bruzzone, S., Gazzerro, E. and Bruno, C.
Laboratory Investigation 103
(3): 100037.
March 2023
MRI of implantation sites using parallel transmission of an optimized radiofrequency excitation vector.
Berangi, M., Kuehne, A., Waiczies, H. and Niendorf, T.
Tomography 9
(2): 603-620.
8 March 2023
The C-terminus of α-synuclein regulates its dynamic cellular internalization by neurexin 1β.
Birol, M., Douzoglou Muñoz, I.I. and Rhoades, E.
Molecular Biology of the Cell 34
(13): br21.
1 December 2023
The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing.
Bischoff, N., Wimberger, S., Kuehn, R., Laugesen, A., Turan, V., Larsen, B.D., Sørensen, C.S., Helin, K., Bennett, E.P., Maresca, M. and Brakebusch, C.
Gene and Genome Editing 5
: 100023.
June 2023
Myocardial injury in patients with acute ischemic stroke detected by cardiovascular magnetic resonance imaging.
Blaszczyk, E., Hellwig, S., Saad, H., Ganeshan, R., Stengl, H., Nolte, C.H., Fiebach, J.B., Endres, M., Kuhnt, J., Gröschel, J., Schulz-Menger, J. and Scheitz, J.F.
European Journal of Radiology 165
: 110908.
7 June 2023
Systemic inflammation and normocytic anemia in DOCK11 deficiency.
Block, J., Rashkova, C., Castanon, I., Zoghi, S., Platon, J., Ardy, R.C., Fujiwara, M., Chaves, B., Schoppmeyer, R., van der Made, C.I., Jimenez Heredia, R., Harms, F.L., Alavi, S., Alsina, L., Sanchez Moreno, P., Ávila Polo, R., Cabrera-Pérez, R., Kostel Bal, S., Pfajfer, L., Ransmayr, B., Mautner, A.K., Kondo, R., Tinnacher, A., Caldera, M., Schuster, M., Domínguez Conde, C., Platzer, R., Salzer, E., Boyer, T., Brunner, H.G., Nooitgedagt-Frons, J.E., Iglesias, E., Deyà-Martinez, A., Camacho-Lovillo, M., Menche, J., Bock, C., Huppa, J.B., Pickl, W.F., Distel, M., Yoder, J.A., Traver, D., Engelhardt, K.R., Linden, T., Kager, L., Hannich, J.T., Hoischen, A., Hambleton, S., Illsinger, S., Da Costa, L., Kutsche, K., Chavoshzadeh, Z., van Buul, J.D., Antón, J., Calzada-Hernández, J., Neth, O., Viaud, J., Nishikimi, A., Dupré, L. and Boztug, K.
New England Journal of Medicine 389
(6): 527-539.
10 August 2023
Space omics and tissue response in astronaut skeletal muscle after short and long duration missions.
Blottner, D., Moriggi, M., Trautmann, G., Hastermann, M., Capitanio, D., Torretta, E., Block, K., Rittweger, J., Limper, U., Gelfi, C. and Salanova, M.
International Journal of Molecular Sciences 24
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2 February 2023
A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich, A., Haenig, C., Neuendorf, N., Blanc, E., Ivanov, A., Kirchner, M., Schleumann, P., Bayraktaroğlu, I., Richter, M., Molenda, C.M., Sporbert, A., Zenkner, M., Schnoegl, S., Suenkel, C., Schneider, L.S., Rybak-Wolf, A., Kochnowsky, B., Byrne, L.M., Wild, E.J., Nielsen, J.E., Dittmar, G., Peters, O., Beule, D. and Wanker, E.E.
Genome Medicine 15
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20 July 2023
Combining metabolic pulse labeling and quantitative proteomics to monitor protein synthesis upon viral infection.
Bogdanow, B., Katsimani, N., Liu, F. and Selbach, M.
Methods in Molecular Biology 2610
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2023
Brain-wide connectivity map of mouse thermosensory cortices.
Bokiniec, P., Whitmire, C.J., Leva, T.M. and Poulet, J.F.A.
Cerebral Cortex 33
(8): 4870-4885.
15 April 2023
Lipid nanoparticle-mediated hit-and-run approaches yield efficient and safe in situ gene editing in human skin.
Bolsoni, J., Liu, D., Mohabatpour, F., Ebner, R., Sadhnani, G., Tafech, B., Leung, J., Shanta, S., An, K., Morin, T., Chen, Y., Arguello, A., Choate, K., Jan, E., Ross, C.J.D., Brambilla, D., Witzigmann, D., Kulkarni, J., Cullis, P.R. and Hedtrich, S.
ACS Nano 17
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14 November 2023
Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors.
Bonifacius, A., Lamottke, B., Tischer-Zimmermann, S., Schultze-Florey, R., Goudeva, L., Heuft, H.G., Arseniev, L., Beier, R., Beutel, G., Cario, G., Fröhlich, B., Greil, J., Hansmann, L., Hasenkamp, J., Höfs, M., Hundsdoerfer, P., Jost, E., Kafa, K., Kriege, O., Kröger, N., Mathas, S., Meisel, R., Nathrath, M., Putkonen, M., Ravens, S., Reinhardt, H.C., Sala, E., Sauer, M.G, Schmitt, C., Schroers, R., Steckel, N.K., Trappe, R.U., Verbeek, M., Wolff, D., Blasczyk, R., Eiz-Vesper, B. and Maecker-Kolhoff, B.
Journal of Clinical Investigation 133
(12): e163548.
15 June 2023
Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy.
Boogerd, C.J., Lacraz, G.P.A., Vértesy, Á., van Kampen, S.J., Perini, I., de Ruiter, H., Versteeg, D., Brodehl, A., van der Kraak, P., Giacca, M., de Jonge, N., Junker, J.P., van Oudenaarden, A., Vink, A. and van Rooij, E.
Cardiovascular Research 119
(2): 477-491.
February 2023
Molecular characterization of the intact mouse muscle spindle using a multi-omics approach.
Bornstein, B., Heinemann-Yerushalmi, L., Krief, S., Adler, R., Dassa, B., Leshkowitz, D., Kim, M.C., Bewick, G., Banks, R.W. and Zelzer, E.
eLife 12
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6 February 2023
90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection.
Bosquillon de Jarcy, L., Akbil, B., Mhlekude, B., Leyens, J., Postmus, D., Harnisch, G., Jansen, J., Schmidt, M.L., Aigner, A., Pott, F., Chua, R.L., Krist, L., Gentile, R., Mühlemann, B., Jones, T.C., Niemeyer, D., Fricke, J., Keil, T., Pischon, T., Janke, J., Conrad, C., Iacobelli, S., Drosten, C., Corman, V.M., Ralser, M., Eils, R., Kurth, F., Sander, L. and Goffinet, C.
Clinical and Experimental Medicine 23
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November 2023
Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness.
Breun, M., Flock, K., Feldheim, J., Nattmann, A., Monoranu, C.M., Herrmann, P., Ernestus, R.I., Löhr, M., Hagemann, C. and Stein, U.
Cancers 15
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14 August 2023
Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.
Briest, F., Noerenberg, D., Hennch, C., Yoshida, K., Hablesreiter, R., Nimo, J., Sasca, D., Kirchner, M., Mansouri, L., Inoue, Y., Wiegand, L., Staiger, A.M., Casadei, B., Korkolopoulou, P., Weiner, J., Lopez-Guillermo, A., Warth, A., Schneider, T., Nagy, Á., Klapper, W., Hummel, M., Kanellis, G., Anagnostopoulos, I., Mertins, P., Bullinger, L., Rosenquist, R., Vassilakopoulos, T.P., Ott, G., Ogawa, S. and Damm, F.
Leukemia 37
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November 2023
Fluid shear stress induces a shift from glycolytic to amino acid pathway in human trophoblasts.
Brugger, B.A., Neuper, L., Guettler, J., Forstner, D., Wernitznig, S., Kummer, D., Lyssy, F., Feichtinger, J., Krappinger, J., El-Heliebi, A., Bonstingl, L., Moser, G., Rodriguez-Blanco, G., Bachkönig, O.A., Gottschalk, B., Gruber, M., Nonn, O., Herse, F., Verlohren, S., Frank, H.G., Barapatre, N., Kampfer, C., Fluhr, H., Desoye, G. and Gauster, M.
Cell and Bioscience 13
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8 September 2023
Immune cell subpopulations and serum neurofilament light chain are associated with increased risk of disease worsening in multiple sclerosis.
Brune-Ingebretsen, S., Høgestøl, E.A., de Rosbo, N.K., Berg-Hansen, P., Brunborg, C., Blennow, K., Zetterberg, H., Paul, F., Uccelli, A., Villoslada, P., Harbo, H.F and Berge, T.
Journal of Neuroimmunology 382
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15 September 2023
Nivolumab and doxorubicin, vinblastine, and dacarbazine in early-stage unfavorable Hodgkin Lymphoma: final analysis of the randomized german Hodgkin study group phase II NIVAHL trial.
Bröckelmann, P.J., Bühnen, I., Meissner, J., Trautmann-Grill, K., Herhaus, P., Halbsguth, T.V., Schaub, V., Kerkhoff, A., Mathas, S., Bormann, M., Dickhut, A., Kaul, H., Fuchs, M., Kobe, C., Baues, C., Borchmann, P., Engert, A. and von Tresckow, B.
Journal of Clinical Oncology 41
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20 February 2023
Health-related quality of life in patients with spinocerebellar ataxia: a validation study of the EQ-5D-3L.
Buchholz, M., Weber, N., Rädke, A., Faber, J., Schmitz-Hübsch, T., Jacobi, H., Xie, F., Klockgether, T. and Michalowsky, B.
Cerebellum 23
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June 2023
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Budu-Aggrey, A., Kilanowski, A., Sobczyk, M.K., Shringarpure, S.S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B.M., Thomas, L.F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J.V.T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A., Jeong, A., Fawcett, K.A., Baurecht, H., Rodriguez, E., Alves, A.C., Kumar, A., Sleiman, P.M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C.J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C.A., Thiering, E., Wu, B., Kress, S., Kothalawala, D.M., Kadalayil, L., Duan, J., Zhang, H., Hadebe, S., Hoffmann, T., Jorgenson, E., Choquet, H., Risch, N., Njølstad, P., Andreassen, O.A., Johansson, S., Almqvist, C., Gong, T., Ullemar, V., Karlsson, R., Magnusson, P.K.E., Szwajda, A., Burchard, E.G., Thyssen, J.P., Hansen, T., Kårhus, L.L., Dantoft, T.M., Jeanrenaud, A.C.S.N., Ghauri, A., Arnold, A., Homuth, G., Lau, S., Nöthen, M.M., Hübner, N., Imboden, M., Visconti, A., Falchi, M., Bataille, V., Hysi, P., Ballardini, N., Boomsma, D.I., Hottenga, J.J., Müller-Nurasyid, M., Ahluwalia, T.S., Stokholm, J., Chawes, B., Schoos, A.M.M., Esplugues, A., Bustamante, M., Raby, B., Arshad, S., German, C., Esko, T., Milani, L.A., Metspalu, A., Terao, C., Abuabara, K., Løset, M., Hveem, K., Jacobsson, B., Pino-Yanes, M., Strachan, D.P., Grarup, N., Linneberg, A., Lee, Y., Probst-Hensch, N., Weidinger, S., Jarvelin, M.R., Melén, E., Hakonarson, H., Irvine, A.D., Jarvis, D., Nijsten, T., Duijts, L., Vonk, J.M., Koppelmann, G.H., Godfrey, K.M., Barton, S.J., Feenstra, B., Pennell, C.E., Sly, P.D., Holt, P.G., Williams, L.K., Bisgaard, H., Bønnelykke, K., Curtin, J., Simpson, A., Murray, C., Schikowski, T., Bunyavanich, S., Weiss, S.T., Holloway, J.W., Min, J.L., Brown, S.J., Standl, M. and Paternoster, L.
Nature Communications 14
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4 October 2023
LRP2 contributes to planar cell polarity-dependent coordination of motile cilia function.
Bunatyan, L., Margineanu, A., Boutin, C., Montcouquiol, M., Bachmann, S., Christensen, E.I., Willnow, T.E. and Christ, A.
Cell and Tissue Research 392
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May 2023
Nonsense mediated decay factor UPF3B is associated with cMyBP-C haploinsufficiency in hypertrophic cardiomyopathy patients.
Burkart, V., Kowalski, K., Disch, A., Hilfiker-Kleiner, D., Lal, S., Dos Remedios, C., Perrot, A., Zeug, A., Ponimaskin, E., Kosanke, M., Dittrich-Breiholz, O., Kraft, T. and Montag, J.
Journal of Molecular and Cellular Cardiology 185
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December 2023
The recurrent atypical e8a2 BCR::ABL1 transcript with insertion of an inverted 55 base pair ABL1 intron 1b sequence: a detailed molecular analysis.
Burmeister, T., Bullinger, L. and le Coutre, P.
Acta Haematologica 146
(5): 413-418.
October 2023
Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment.
Burmeister, T., Gröger, D., Gökbuget, N., Spriewald, B., Starck, M., Elmaagacli, A., Hoelzer, D., Keller, U. and Schwartz, S.
Scientific Reports 13
(1): 15167.
13 September 2023
Inferior outcomes of EU versus US patients treated with CD19 CAR-T for relapsed/refractory large B-cell lymphoma: association with differences in tumor burden, systemic inflammation, bridging therapy utilization, and CAR-T product use.
Bücklein, V., Perez, A., Rejeski, K., Iacoboni, G., Jurinovic, V., Holtick, U., Penack, O., Kharboutli, S., Blumenberg, V., Ackermann, J., Frölich, L., Johnson, G., Patel, K., Arciola, B., Mhaskar, R., Wood, A., Schmidt, C., Albanyan, O., Gödel, P., Hoster, E., Bullinger, L., Mackensen, A., Locke, F., von Bergwelt, M., Barba, P., Subklewe, M. and Jain, M.D.
HemaSphere 7
(8): e907.
August 2023
Synapsin autoantibodies during pregnancy are associated with fetal abnormalities.
Bünger, I., Talucci, I., Kreye, J., Höltje, M., Makridis, K.L., Foverskov Rasmussen, H., van Hoof, S., Cordero-Gomez, C., Ullrich, T., Sedlin, E., Kreissner, K.O., Hoffmann, C., Milovanovic, D., Turko, P., Paul, F., Meckies, J., Verlohren, S., Henrich, W., Chaoui, R., Maric, H.M., Kaindl, A.M. and Prüss, H.
Brain, Behavior & Immunity - Health 33
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November 2023
Autoantibodies targeting G protein-coupled receptors: an evolving history in autoimmunity. Report of the 4th international symposium.
Cabral-Marques, O., Moll, G., Catar, R., Preuß, B., Bankamp, L., Pecher, A.C., Henes, J., Klein, R., Kamalanathan, A.S., Akbarzadeh, R., van Oostveen, W., Hohberger, B., Endres, M., Koolmoes, B., Levarht, N., Postma, R., van Duinen, V., van Zonneveld, A.J., de Vries-Bouwstra, J., Fehres, C., Tran, F., do Vale, F.Y.N., da Silva Souza, K.B., Filgueiras, I.S., Schimke, L.F., Baiocchi, G.C., de Miranda, G.C., da Fonseca, D.L.M., Freire, P.P., Hackel, A.M., Grasshoff, H., Stähle, A., Müller, A., Dechend, R., Yu, X., Petersen, F., Sotzny, F., Sakmar, T.P., Ochs, H.D, Schulze-Forster, Kai, Heidecke, H., Scheibenbogen, C., Shoenfeld, Y. and Riemekasten, G.
Autoimmunity Reviews 22
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May 2023
Optical coherence tomography reflects clinically relevant gray matter damage in patients with multiple sclerosis.
Cagol, A., Fuertes, N.C., Stoessel, M., Barakovic, M., Schaedelin, S., D'Souza, M., Würfel, J., Brandt, A.U., Kappos, L., Sprenger, T., Naegelin, Y., Kuhle, J., Granziera, C. and Papadopoulou, A.
Journal of Neurology 270
(4): 2139-2148.
April 2023
AT1-AA infusion during pregnancy impairs CBF autoregulation postpartum.
Campbell, N., Strong, L., Fang, X., Border, J.J., Herrock, O., Turner, T., Deer, E., Amaral, L., Dechend, R., Roman, R.J. and LaMarca, B.
International Journal of Cerebrovascular Disease and Stroke 6
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17 July 2023
Monitoring kidney size to interpret MRI-based assessment of renal oxygenation in acute pathophysiological scenarios.
Cantow, K., Gladytz, T., Millward, J.M., Waiczies, S., Niendorf, T. and Seeliger, E.
Acta Physiologica 237
(2): e13868.
February 2023
Impact of high salt-intake on a natural gut ecosystem in wildling mice.
Cardilli, A., Hamad, I., Dyczko, A., Thijs, S., Vangronsveld, J., Müller, D.N., Rosshart, S.P. and Kleinewietfeld, M.
Nutrients 15
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23 March 2023
Mortality of neuromyelitis optica spectrum disorder patients in an Argentinean population: a study from the RelevarEM registry.
Carnero Contentti, E., Lopez, P.A., Pettinicchi, J.P., Criniti, J., Pappolla, A., Miguez, J., Cristiano, E., Patrucco, L., Liwacki, S., Tkachuk, V., Balbuena, M.E., Vrech, C., Deri, N., Correale, J., Marrodan, M., Ysrraelit, M.C., Leguizamon, F., Luetic, G., Menichini, M.L., Tavolini, D., Mainella, C., Zanga, G., Burgos, M., Hryb, J., Barboza, A., Lazaro, L., Alonso, R., Fernández Liguori, N., Nadur, D., Alonso Serena, M., Caride, A., Paul, F. and Rojas, J.I.
Multiple Sclerosis Journal Experimental Translational and Clinical 9
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17 October 2023
Frequency of new asymptomatic MRI lesions during attacks and follow-up of patients with NMOSD in a real-world setting.
Carnero Contentti, E., Lopez, P.A., Tkachuk, V., Vrech, C., Zarate, M.A., Correale, J., Deri, N., Luetic, G., Marrodan, M., Pagani Cassara, F., Tavolini, D., Ysrraelit, M.C., Balbuena, M.E., Hryb, J., Chiganer, E., Leguizamon, F., Knorre, E., Zanga, G., Pestchanker, C., Barboza, A., Nadur, D., Cristiano, E., Patrucco, L., Alonso, R., Alonso Serena, M., Paul, F. and Rojas, J.I.
Multiple Sclerosis Journal 29
(10): 1240-1249.
September 2023
The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity.
Carriquí-Madroñal, B., Sheldon, J., Duven, M., Stegmann, C., Cirksena, K., Wyler, E., Zapatero-Belinchón, F.J., Vondran, F.W.R. and Gerold, G.
PLoS Pathogens 19
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15 November 2023
Cerebrovascular G(i) proteins protect against brain hypoperfusion and collateral failure in cerebral ischemia.
Castaneda-Vega, S., Beer-Hammer, S., Leiss, V., Napieczyńska, H., Vuozzo, M., Schmid, A.M., Zeng, H., He, Y., Kohlhofer, U., Gonzalez-Menendez, I., Quintanilla-Martinez, L., Hempel, J.M., Gollasch, M., Yu, X., Pichler, B.J. and Nürnberg, B.
Molecular Imaging and Biology 25
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April 2023
Brown adipose tissue transcriptome unveils an important role of the Beta-alanine/alamandine receptor, MrgD, in metabolism.
Cerri, G.C., Santos, S.H.S., Bader, M. and Dos Santos, R.A.S.
Journal of nutritional biochemistry 114
: 109268.
April 2023
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.
Chamorro González, R., Conrad, T., Stöber, M.C., Xu, R., Giurgiu, M., Rodriguez-Fos, E., Kasack, K., Brückner, L., van Leen, E., Helmsauer, K., Dorado Garcia, H., Stefanova, M.E., Hung, K.L., Bei, Y., Schmelz, K., Lodrini, M., Mundlos, S., Chang, H.Y., Deubzer, H.E., Sauer, S., Eggert, A., Schulte, J.H., Schwarz, R.F., Haase, K., Koche, R.P. and Henssen, A.G.
Nature Genetics 55
(5): 880-890.
May 2023
Determining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging.
Chang, S.Y.S., Dijkman, P.M., Wiessing, S.A. and Kudryashev, M.
Scientific Reports 13
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17 July 2023
XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes.
Chatzinikolaou, G., Stratigi, K., Siametis, A., Goulielmaki, E., Akalestou-Clocher, A., Tsamardinos, I., Topalis, P., Austin, C., Bouwman, B.A.M., Crosetto, N., Altmüller, J. and Garinis, G.A.
Science Advances 9
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10 November 2023
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Chee, J.M., Lanoue, L., Clary, D., Higgins, K., Bower, L., Flenniken, A., Guo, R., Adams, D.J., Bosch, F., Braun, R.E., Brown, S.D.M., Chin, H.J.G., Dickinson, M.E., Hsu, C.W., Dobbie, M., Gao, X., Galande, S., Grobler, A., Heaney, J.D., Herault, Y., de Angelis, M.H., Mammano, F., Nutter, L.M.J, Parkinson, H., Qin, C., Shiroishi, T., Sedlacek, R., Seong, J.K., Xu, Y., Brooks, B., McKerlie, C., Lloyd, K.C.K., Westerberg, H. and Moshiri, A.
BMC Biology 21
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3 February 2023
Do early relapses predict the risk of long-term relapsing disease in an adult and paediatric cohort with MOGAD?
Chen, B., Gomez-Figueroa, E., Redenbaugh, V., Francis, A., Satukijchai, C., Wu, Y., Messina, S., Sa, M., Woodhall, M., Paul, F., Robertson, N.P., Lim, M., Wassmer, E., Kneen, R., Huda, S., Blain, C., Halfpenny, C., Hemingway, C., O'Sullivan, E., Hobart, J., Fisniku, L.K., Martin, R.J., Dobson, R., Cooper, S.A., Williams, V., Waters, P., Chen, J.J., Pittock, S.J., Ramdas, S., Leite, M.I., Flanagan, E.P., Geraldes, R. and Palace, J.
Annals of Neurology 94
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September 2023
LongDat: an R package for covariate-sensitive longitudinal analysis of high-dimensional data.
Chen, C.Y., Löber, U. and Forslund, S.K.
Bioinformatics Advances 3
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18 May 2023
Mepolizumab as an effective treatment in a case of hypophysitis in eosinophilic granulomatosis with polyangiitis.
Chen, J., Alexander, T., Walter-Rittel, T., Ziagaki, A. and Siffrin, V.
Therapeutic Advances in Neurological Disorders 16
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2023
TREM2 promotes glioma progression and angiogenesis mediated by microglia/brain macrophages.
Chen, X., Zhao, Y., Huang, Y., Zhu, K., Zeng, F., Zhao, J., Zhang, H., Zhu, X., Kettenmann, H. and Xiang, X.
Glia 71
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November 2023
Novel candidate regulators and developmental trajectory of pituitary thyrotropes.
Cheung, L.Y.M., Menage, L., Rizzoti, K., Hamilton, G., Dumontet, T., Basham, K., Daly, A.Z., Brinkmeier, M.L., Masser, B.E., Treier, M., Cobb, J., Delogu, A., Lovell-Badge, R., Hammer, G.D. and Camper, S.A.
Endocrinology 164
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June 2023
Translation and validation of the multiple sclerosis walking scale 12 for the German population - the MSWS-12/D.
Chorschew, A., Kesgin, F., Bellmann-Strobl, J., Flachenecker, P., Schiffmann, I., Rosenthal, F., Althoff, P., Drebinger, D., Arsenova, R., Rasche, L., Dorsch, E.M., Heesen, C., Paul, F., Stellmann, J.P. and Schmitz-Hübsch, T.
Health and Quality of Life Outcomes 21
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9 October 2023
Physics-based polymer models to probe chromosome structure in single molecules.
Conte, M., Chiariello, A.M., Bianco, S., Esposito, A., Abraham, A. and Nicodemi, M.
Methods in Molecular Biology 2655
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2023
Clinical and MRI measures to identify non-acute MOG-antibody disease in adults.
Cortese, R., Battaglini, M., Prados, F., Bianchi, A., Haider, L., Jacob, A., Palace, J., Messina, S., Paul, F., Wuerfel, J., Marignier, R., Durand-Dubief, F., de Medeiros Rimkus, C., Callegaro, D., Sato, D.K., Filippi, M., Rocca, M.A., Cacciaguerra, L., Rovira, A., Sastre-Garriga, J., Arrambide, G., Liu, Y., Duan, Y., Gasperini, C., Tortorella, C., Ruggieri, S., Amato, M.P., Ulivelli, M., Groppa, S., Grothe, M., Llufriu, S., Sepulveda, M., Lukas, C., Bellenberg, B., Schneider, R., Sowa, P., Celius, E.G., Proebstel, A.K., Yaldizli, Ö., Müller, J., Stankoff, B., Bodini, B., Carmisciano, L., Sormani, M.P., Barkhof, F., De Stefano, N. and Ciccarelli, O.
Brain 146
(6): 2489-2501.
June 2023
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.
Costanzo, M.C., von Grotthuss, M., Massung, J., Jang, D., Caulkins, L., Koesterer, R., Gilbert, C., Welch, R.P., Kudtarkar, P., Hoang, Q., Boughton, A.P., Singh, P., Sun, Y., Duby, M., Moriondo, A., Nguyen, T., Smadbeck, P., Alexander, B.R., Brandes, M.K., Carmichael, M., Dornbos, P., Green, T., Huellas-Bruskiewicz, K.C., Ji, Y., Kluge, A., McMahon, A.C., Mercader, J.M., Ruebenacker, O., Sengupta, S., Spalding, D., Taliun, D., Smith, P., Thomas, M.K., Akolkar, B., Brosnan, M.J., Cherkas, A., Chu, A.Y., Fauman, E.B., Fox, C.S., Kamphaus, T.N., Miller, M.R., Nguyen, L., Parsa, A., Reilly, D.F., Ruetten, H., Wholley, D., Zaghloul, N.A., Abecasis, G.R., Altshuler, D., Keane, T.M., McCarthy, M.I., Gaulton, K.J., Florez, J.C., Boehnke, M., Burtt, N.P. and Flannick, J.
Cell Metabolism 35
(4): 695-710.e6.
4 April 2023
Association of the human gut microbiota with vascular stiffness.
Cuadrat, R.R.C., Goris, T., Birukov, A., Eichelmann, F., Andrade, B.G.N., Bang, C., Franke, A., Wittenbecher, C. and Schulze, M.B.
Scientific Reports 13
(1): 13348.
16 August 2023
Cardiovascular disease biomarkers derived from circulating cell-free DNA methylation.
Cuadrat, R.R.C., Kratzer, A., Arnal, H.G., Rathgeber, A.C., Wreczycka, K., Blume, A., Gündüz, I.B., Ebenal, V., Mauno, T., Osberg, B., Moobed, M., Hartung, J., Jakobs, K., Seppelt, C., Meteva, D., Haghikia, A., Leistner, D.M., Landmesser, Ulf and Akalin, A.
NAR Genomics and Bioinformatics 5
(2): lqad061.
June 2023
Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing.
Cui, L., Yang, B., Xiao, S., Gao, J., Baud, A., Graham, D., McBride, M., Dominiczak, A., Schafer, S., Aumatell, R.L., Mont, C., Teruel, A.F., Hübner, N., Flint, J., Mott, R. and Huang, L.
Genome Biology 24
(1): 215.
29 September 2023
Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.
Côrte-Real, B.F., Hamad, I., Arroyo Hornero, R., Geisberger, S., Roels, J., Van Zeebroeck, L., Dyczko, A., van Gisbergen, M.W., Kurniawan, H., Wagner, A., Yosef, N., Weiss, S.N.Y., Schmetterer, K.G., Schröder, A., Krampert, L., Haase, S., Bartolomaeus, H., Hellings, N., Saeys, Y., Dubois, L.J., Brenner, D., Kempa, S., Hafler, D.A., Stegbauer, J., Linker, R.A., Jantsch, J., Müller, D.N. and Kleinewietfeld, M.
Cell Metabolism 35
(2): 299-315.
7 February 2023
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Danielli, S.G., Porpiglia, E., De Micheli, A.J., Navarro, N., Zellinger, M.J., Bechtold, I., Kisele, S., Volken, L., Marques, J.G., Kasper, S., Bode, P.K., Henssen, A.G., Gürgen, D., Delattre, O., Surdez, D., Roma, J., Bühlmann, P., Blau, H.M., Wachtel, M. and Schäfer, B.W.
Science Advances 9
(6): eade9238.
10 February 2023
Atrial natriuretic peptide and leptin interactions in healthy men.
Daniels, M.A., Fischer-Posovszky, P., Boschmann, M., Jumpertz-von Schwartzenberg, R., Müller, T.D., Sandforth, L., Frank-Podlech, S., Hülskämper, S., Peter, A., Wabitsch, M., Jordan, J. and Birkenfeld, A.L.
Frontiers in Endocrinology 14
: 1195677.
30 June 2023
Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture.
Dasgupta, S., Dayagi, D.Y., Haimovich, G., Wyler, E., Olender, T., Singer, R.H., Landthaler, M. and Gerst, J.E.
eLife 12
: e83584.
30 May 2023
External mechanical loading overrules cell-cell mechanical communication in sprouting angiogenesis during early bone regeneration.
Dazzi, C., Mehl, J., Benamar, M., Gerhardt, H., Knaus, P., Duda, G.N. and Checa, S.
PLoS Computational Biology 19
(11): e1011647.
13 November 2023
Influenzaimpfung – Mehr als nur Influenzaschutz [Influenza vaccination – more than just protection against the flu].
Dechend, R.
Kardiologie 17
(6): 434-440.
December 2023
In vitro galactose impairs energy metabolism in the brain of young rats: protective role of antioxidants.
Delwing-de Lima, D., Sasso, S., Delwing-Dal Magro, D., Pereira, N.R., Rodrigues, A.F., Schmitz, F., Manoel Pereira, E., Schramm do Nascimento, M.A. and Wyse, A.T.S.
Nucleosides Nucleotides & Nucleic Acids 42
(12): 967-985.
2023
Small molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy.
Demel, U.M., Wirth, M., Yousefian, S., Zhang, L., Isaakidis, K., Dönig, J., Böger, M., Singh, N., Köse, H., Haas, S., Müller, S., Schick, M. and Keller, U.
Haematologica 108
(2): 555-567.
February 2023
Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.
Denkinger, C.M., Janssen, M., Schäkel, U., Gall, J., Leo, A., Stelmach, P., Weber, S.F., Krisam, J., Baumann, L., Stermann, J., Merle, U., Weigand, M.A., Nusshag, C., Bullinger, L., Schrezenmeier, J.F., Bornhäuser, M., Alakel, N., Witzke, O., Wolf, T., Vehreschild, M.J.G.T., Schmiedel, S., Addo, M.M., Herth, F., Kreuter, M., Tepasse, P.R., Hertenstein, B., Hänel, M., Morgner, A., Kiehl, M., Hopfer, O., Wattad, M.A., Schimanski, C.C., Celik, C., Pohle, T., Ruhe, M., Kern, W.V., Schmitt, A., Lorenz, H.M., Souto-Carneiro, M., Gaeddert, M., Halama, N., Meuer, S., Kräusslich, H.G., Müller, B., Schnitzler, P., Parthé, S., Bartenschlager, R., Gronkowski, M., Klemmer, J., Schmitt, M., Dreger, P., Kriegsmann, K., Schlenk, Ri.F. and Müller-Tidow, C.
Nature Cancer 4
(1): 96-107.
January 2023
HMGXB4 targets Sleeping Beauty transposition to germinal stem cells.
Devaraj, A., Singh, M., Narayanavari, S.A., Yong, G., Chen, J., Wang, J., Becker, M., Walisko, O., Schorn, A., Cseresznyés, Z., Raskó, T., Radscheit, K., Selbach, M., Ivics, Z. and Izsvak, Z.
International Journal of Molecular Sciences 24
(8): 7283.
14 April 2023
Liver resection modulates hepatic chemokine levels in breast cancer.
Dincer, H.A., Horzum, U., Kursunel, M.A., Yoyen-Ermis, D., Ermis, E., Ozogul, E., Akkapulu, N., Esendagli, G. and Karakoc, D.
Surgery 174
(2): 277-282.
August 2023
Old discovery leading to new era: metabolic imaging of cancer with Deuterium MRI.
Ding, H., Haroon, A., Wan, S., Niendorf, T. and Adeleke, S.
Magnetochemistry 9
(1): 6.
January 2023
Retained functional normal and preleukemic HSCs at diagnosis are associated to good prognosis in DNMT3Amut NPM1mut AMLs.
Donato, E., Correia, N.C., Andresen, C., Karpova, D., Würth, R., Klein, C., Sohn, M., Przybylla, A., Zeisberger, P., Rothfelder, K., Salih, H.R., Bonig, H., Stasik, S., Röllig, C., Dolnik, A., Bullinger, L., Buchholz, F., Thiede, C.D., Hübschmann, D. and Trumpp, A.
Blood Advances 7
(6): 1011-1018.
28 March 2023
N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness.
Dong, Hongliang, Zeng, Lili, Chen, Weiwei, Zhang, Qian, Wang, Fei, Wu, Yan, Cui, Bingjie, Qi, Jingjing, Zhang, Xin, Liu, Cuilan, Deng, Jiong, Yu, Y., Schmitt, C.A. and Du, Jing
Cell Death Discovery 9
(1): 149.
6 May 2023
Progression events defined by home-based assessment of motor function in multiple sclerosis: protocol of a prospective study.
Dorsch, E.M., Röhling, H.M., Zocholl, D., Hafermann, L., Paul, F. and Schmitz-Hübsch, T.
Frontiers in Neurology 14
: 1258635.
10 October 2023
Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
Döhner, H., Weber, D., Krzykalla, J., Fiedler, W., Kühn, M.W.M., Schroeder, T., Mayer, K., Lübbert, M., Wattad, M., Götze, K., Fransecky, L., Koller, E., Wulf, G., Schleicher, J., Ringhoffer, M., Greil, R., Hertenstein, B., Krauter, J., Martens, U.M., Nachbaur, D., Samra, M.A., Machherndl-Spandl, S., Basara, N., Leis, C., Schrade, A., Kapp-Schwoerer, S., Cocciardi, S., Bullinger, L., Thol, F., Heuser, M., Paschka, P., Gaidzik, V.I., Saadati, M., Benner, A., Schlenk, R.F., Döhner, K. and Ganser, A.
Lancet Haematology 10
(7): e495-e509.
July 2023
Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Dönig, J., Mende, H., Davila Gallesio, J., Wagner, K., Hotz, P., Schunck, K., Piller, T., Hölper, S., Uhan, S., Kaulich, M., Wirth, M., Keller, U., Tascher, G., Bohnsack, K.E. and Müller, S.
Nature Communications 14
(1): 8121.
8 December 2023
Trends and perspectives for improving quality of chronic kidney disease care: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Eckardt, K.U., Delgado, C., Heerspink, H.J.L., Pecoits-Filho, R., Ricardo, A.C., Stengel, B., Tonelli, M., Cheung, M., Jadoul, M., Winkelmayer, W.C. and Kramer, H.
Kidney International 104
(5): 888-903.
November 2023
Kommentar zu den Leitlinien 2022 der ESC zu ventrikulären Arrhythmien und Prävention des plötzlichen Herztodes [Comments on the 2022 guidelines of the ESC on ventricular arrhythmias and prevention of sudden cardiac death].
Eckardt, L., Könemann, H., Bosch, R., Deneke, T., Falk, V., Perings, C., Schulz-Menger, J. and Meyer, C.
Kardiologie 17
(1): 27-38.
3 February 2023
Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Eifert, T., Hsu, C.J., Becker, A.L., Graessle, S., Horne, A., Bemmann, F., Zhang, Q., Heuser, M., Vasioukhin, V., Scholl, S., Hochhaus, A., Siegerist, F., Endlich, N., Bullinger, L., Lane, S.W., Haas, S., Schnoeder, T.M and Heidel, F.H.
Leukemia 37
(10): 2027-2035.
October 2023
"Biofeedback-based return to sport": individualization through objective assessments.
Ekizos, A. and Santuz, A.
Frontiers in Physiology 14
: 1185556.
12 June 2023
Telemedicine in neuromuscular diseases during Covid-19 pandemic: ERN-NMD European survey.
El-Hassar, L., Amara, A., Sanson, B., Lacatus, O., Amir Belhouchet, A., Kroneman, M., Claeys, K., Plançon, J.P., Rodolico, C., Primiano, G., Trojsi, F., Filosto, M., Mongini, T.E., Bortolani, S., Monforte, M., Carraro, E., Maggi, L., Ricci, F., Silani, V., Orsucci, D., Créange, A., Péréon, Y., Stojkovic, T., van der Beek, N.A.M.E., Toscano, A., Pareyson, D., Attarian, S., Van den Bergh, P.Y.K., Remiche, G., Hoeijmakers, J.G.J., Badrising, U., Voermans, N.C., Kaindl, A.M., Schara-Schmidt, U., Schoser, B., Gazzerro, E., Haberlová, Ja., Voháňka, S., Pál, E., Molnar, M. J., Leonardis, L., Tournev, I.L., Osorio, A.N., Olivé, M., Muelas, N., Alonso-Perez, J., de Visser, M., Siciliano, G. and Sacconi, S.
Journal of Neuromuscular Diseases 10
(2): 173-184.
7 March 2023
Parallel in-depth analysis of repeat expansions in ataxia patients by long-read sequencing.
Erdmann, H., Schöberl, F., Giurgiu, M., Leal Silva, R.M., Scholz, V., Scharf, F., Wendlandt, M., Kleinle, S., Deschauer, M., Nübling, G., Heide, W., Babacan, S.S., Schneider, C., Neuhann, T., Hahn, K., Schoser, B., Holinski-Feder, E., Wolf, D.A. and Abicht, A.
Brain 146
(5): 1831-1843.
May 2023
Germline C1GALT1C1 mutation causes a multisystem chaperonopathy.
Erger, F., Aryal, R.P., Reusch, B., Matsumoto, Y., Meyer, R., Zeng, J., Knopp, C., Noel, M., Muerner, L., Wenzel, A., Kohl, S., Tschernoster, N., Rappl, G., Rouvet, I., Schröder-Braunstein, J., Seibert, F.S., Thiele, H., Häusler, M.G., Weber, L.T., Büttner-Herold, M., Elbracht, M., Cummings, S.F., Altmüller, J., Habbig, S., Cummings, R.D. and Beck, B.B.
Proceedings of the National Academy of Sciences of the United States of America 120
(22): e2211087120.
30 May 2023
High tissue-sodium associates with systemic inflammation and insulin resistance in obese individuals.
Ertuglu, L., Sahinoz, M., Alsouqi, A., Deger, S.M., Guide, A., Stewart, T.G., Pike, M., Robinson-Cohen, C., Akwo, E., Pridmore, M., Crescenzi, R., Madhur, M.S., Harrison, D.G., Luft, F.C., Titze, J. and Ikizler, T.A.
Nutrition Metabolism and Cardiovascular Diseases 33
(7): 1398-1406.
July 2023
Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging.
Espiritu, J., Berangi, M., Cwieka, H., Iskhakova, K., Kuehne, A., Florian Wieland, D.C., Zeller-Plumhoff, B., Niendorf, T., Willumeit-Römer, R. and Seitz, J.M.
Bioactive Materials 25
: 86-94.
23 January 2023
Predictors of lower exercise capacity in patients with cancer.
Evertz, R., Diehl, C., Gödde, K., Valentova, M., Garfias-Veitl, T., Overbeck, T.R., Braulke, F., Lena, A., Hadzibegovic, S., Bleckmann, A., Keller, U., Landmesser, U., König, A.O., Hasenfuss, G., Schuster, A., Anker, M.S. and von Haehling, S.
Scientific Reports 13
(1): 14861.
8 September 2023
Cardiovascular and metabolic determinants of quality of life in patients with cancer.
Evertz, R., Gödde, K., Diehl, C., Valentova, M., Garfias-Veitl, T., Braulke, F., Wulf, G.G., Overbeck, T.R., Bleckmann, A., König, A.O., Weinländer, P., Potthoff, S., Hadzibegovic, S., Lena, A., Keller, U., Landmesser, U., Schuster, A., Anker, M.S., Hasenfuß, G. and von Haehling, S.
ESC Heart Failure 10
(1): 167-176.
February 2023
IL-33 expression is lower in current smokers at both transcriptomic and protein level.
Faiz, A., Mahbub, R.M., Boedijono, F.S., Tomassen, M.I., Kooistra, W., Timens, W., Nawijn, M., Hansbro, P.M., Johansen, M.D., Pouwels, S.D., Heijink, I.H., Massip, F., de Biase, M.S., Schwarz, R.F., Adcock, I.M., Chung, K.F., van der Does, A., Hiemstra, P.S., Goulaouic, H., Xing, H., Abdulai, R., de Rinaldis, E., Cunoosamy, D., Harel, S., Lederer, D., Nivens, M.C., Wark, P.A., Kerstjens, H.A.M., Hylkema, M.N., Brandsma, C.A. and van den Berge, M.
American Journal of Respiratory and Critical Care Medicine 208
(10): 1075-1087.
15 November 2023
Machine learning-based ozone and PM2.5 forecasting: application to multiple AQS sites in the Pacific Northwest.
Fan, K., Dhammapala, R., Harrington, K., Lamb, B. and Lee, Y.
Frontiers in Big Data 6
: 1124148.
24 February 2023
Machine learning-based prediction of clinical outcomes after first-ever ischemic stroke.
Fast, L., Temuulen, U., Villringer, K., Kufner, A., Ali, H.F., Siebert, E., Huo, S., Piper, S.K., Sperber, P.S., Liman, T., Endres, M. and Ritter, K.
Frontiers in Neurology 14
: 1114360.
21 February 2023
Spatially and temporally distinct patterns of expression for VPS10P domain receptors in human cerebral organoids.
Febbraro, F., Andersen, H.H.B., Kitt, M.M. and Willnow, T.E.
Frontiers in Cell and Developmental Biology 11
: 2023.
29 September 2023
Metabolic syndrome and the risk of postoperative delirium and postoperative cognitive dysfunction: a multi-centre cohort study.
Feinkohl, I., Janke, J., Slooter, A.J.C., Winterer, G., Spies, C. and Pischon, T.
British Journal of Anaesthesia 131
(2): 338-347.
August 2023
Amplicon sequencing allows differential quantification of closely related parasite species: an example from rodent Coccidia (Eimeria).
Ferreira, S.C.M., Jarquín-Díaz, V.H. and Heitlinger, E.
Parasites and Vectors 16
(1): 204.
17 June 2023
Thioester and oxyester linkages in the ubiquitin system.
Ferri-Blazquez, A., Jarosch, E. and Sommer, T.
Methods in Molecular Biology 2602
: 3-18.
2023
Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma.
Finotto, L., Cole, B., Giese, W., Baumann, E., Claeys, A., Vanmechelen, M., Decraene, B., Derweduwe, M., Dubroja Lakic, N., Shankar, G., Nagathihalli Kantharaju, M., Albrecht, J.P., Geudens, I., Stanchi, F., Ligon, K.L., Boeckx, B., Lambrechts, D., Harrington, K., Van Den Bosch, L., De Vleeschouwer, S., De Smet, F. and Gerhardt, H.
EMBO Molecular Medicine 15
(11): e18144.
8 November 2023
Identification of radiomic biomarkers in a set of four skeletal muscle groups on Dixon MRI of the NAKO MR study.
Fischer, M., Küstner, T., Pappa, S., Niendorf, T., Pischon, T., Kröncke, T., Bette, S., Schramm, S., Schmidt, B., Haubold, J., Nensa, F., Nonnenmacher, T., Palm, V., Bamberg, F., Kiefer, L., Schick, F. and Yang, B.
BMC Medical Imaging 23
(1): 104.
8 August 2023
Trail making test B in postoperative delirium: a replication study.
Fislage, M., Feinkohl, I., Borchers, F., Heinrich, M., Pischon, T., Veldhuijzen, D.S., Slooter, A.J.C., Spies, C.D., Winterer, G. and Zacharias, N.
BJA Open 8
: 100239.
December 2023
Preoperative thalamus volume is not associated with preoperative cognitive impairment (preCI) or postoperative cognitive dysfunction (POCD).
Fislage, M., Feinkohl, I., Borchers, F., Pischon, T., Spies, C.D., Winterer, G. and Zacharias, N.
Scientific Reports 13
(1): 11732.
20 July 2023
Potential contribution of ancient introgression to the evolution of a derived reproductive strategy in ricefishes.
Flury, J.M., Meusemann, K., Martin, S., Hilgers, L., Spanke, T., Böhne, A., Herder, F., Mokodongan, D., Altmüller, J., Wowor, D., Misof, B., Nolte, A.W. and Schwarzer, J.
Genome Biology and Evolution 15
(8): evad138.
29 August 2023
Occurrence and risk factors of relapse activity after vaccination against COVID-19 in people with multiple sclerosis: 1-year follow-up results from a nationwide longitudinal observational study.
Fneish, F., Frahm, N., Peters, M., Ellenberger, D., Haas, J., Löbermann, M., Pöhlau, D., Röper, A.L., Schilling, S., Stahmann, A., Temmes, H., Paul, F. and Zettl, U.K.
Vaccines 11
(12): 1859.
16 December 2023
TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients.
Foddis, M., Blumenau, S., Holtgrewe, M., Paquette, K., Westra, K., Alonso, I., Macario, M.d.C., Morgadinho, A.S., Velon, A.G., Santo, G., Santana, I., Mönkäre, S., Kuuluvainen, L., Schleutker, J., Pöyhönen, M., Myllykangas, L., Pavlovic, A., Kostic, V., Dobricic, V., Lohmann, E., Hanagasi, H., Santos, M., Guven, G., Bilgic, B., Bras, J., Beule, D., Dirnagl, U., Guerreiro, R. and Sassi, C.
Neurobiology of Aging 123
: 208-215.
March 2023
A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions.
Fonseca, C.G., Silvério, V., Barata, D., Giese, W., Gerhardt, H., Cardoso, S. and Franco, C.A.
Microsystems & Nanoengineering 9
: 114.
15 September 2023
Advancements in pulsed stable isotope-resolved metabolomics.
Forbes, M., Geisberger, S., Pietzke, M., Mastrobuoni, G. and Kempa, S.
Handbook of Experimental Pharmacology 277
: 165-180.
3 March 2023
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency.
Fornes, O., Jia, A., Kuehn, H.S., Min, Q., Pannicke, U., Schleussner, N., Thouenon, R., Yu, Z., de Los Angeles Astbury, M., Biggs, C.M., Galicchio, M., Garcia-Campos, J.A., Gismondi, S., Gonzalez Villarreal, G., Hildebrand, K.J., Hönig, M., Hou, J., Moshous, D., Pittaluga, S., Qian, X., Rozmus, J., Schulz, A.S., Staines-Boone, A.T., Sun, B., Sun, J., Uwe, S., Venegas-Montoya, E., Wang, W., Wang, X., Ying, W., Zhai, X., Zhou, Q., Akalin, A., André, I., Barth, T.F.E., Baumann, B., Brüstle, A., Burgio, G., Bustamante, J.C., Casanova, J.L., Casarotto, M.G., Cavazzana, M., Chentout, L., Cockburn, I.A., Costanza, M., Cui, C., Daumke, O., Del Bel, K.L., Eibel, H., Feng, X., Franke, V., Gebhardt, J.C.M., Götz, A., Grunwald, S., Hoareau, B., Hughes, T.R., Jacobsen, E.M., Janz, M., Jolma, A., Lagresle-Peyrou, C., Lai, N., Li, Y., Lin, S., Lu, H.Y., Lugo-Reyes, S.O., Meng, X., Möller, P., Moreno-Corona, N., Niemela, J.E., Novakovsky, G., Perez-Caraballo, J.J., Picard, C., Poggi, L., Puig-Lombardi, M.E., Randall, K.L., Reisser, A., Schmitt, Y., Seneviratne, S., Sharma, M., Stoddard, J., Sundararaj, S., Sutton, H., Tran, L.Q., Wang, Y., Wasserman, W.W., Wen, Z., Winkler, W., Xiong, E., Yang, A.W.H., Yu, M., Zhang, L., Zhang, H., Zhao, Q., Zhen, X., Enders, A., Kracker, S., Martinez-Barricarte, R., Mathas, S., Rosenzweig, S.D., Schwarz, K., Turvey, S.E. and Wang, J.Y.
Science Immunology 8
(79): eade7953.
January 2023
CD39 abrogates platelet-derived factors induced IL-1β expression in the human placenta.
Forstner, D., Guettler, J., Brugger, B.A., Lyssy, F., Neuper, L., Daxboeck, C., Cvirn, G., Fuchs, J., Kraeker, K., Frolova, A., Valdes, D.S., Stern, C., Hirschmugl, B., Fluhr, H., Wadsack, C., Huppertz, B., Nonn, O., Herse, F. and Gauster, M.
Frontiers in Cell and Developmental Biology 11
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2023
Molecular mechanisms underlying the beneficial effects of exercise and dietary interventions in the prevention of cardiometabolic diseases.
Forte, M., Rodolico, D., Ameri, P., Catalucci, D., Chimenti, C., Crotti, L., Schirone, L., Pingitore, A., Torella, D., Iacovone, G., Valenti, V., Schiattarella, G.G., Perrino, C. and Sciarretta, S.
Journal of Cardiovascular Medicine 24
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1 April 2023
Frequency and predictors of relapses following SARS-CoV-2 vaccination in patients with multiple sclerosis: interim results from a longitudinal observational study.
Frahm, N., Fneish, F., Ellenberger, D., Haas, J., Löbermann, M., Peters, M., Pöhlau, D., Röper, A.L., Schilling, S., Stahmann, A., Temmes, H., Paul, F. and Zettl, U.K.
Journal of Clinical Medicine 12
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24 May 2023
The evolution of lung cancer and impact of subclonal selection in TRACERx.
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Nature 616
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20 April 2023
Branch point strength controls species-specific CAMK2B alternative splicing and regulates LTP.
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March 2023
CAR links hypoxia signaling to improved survival after myocardial infarction.
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Experimental and Molecular Medicine 55
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March 2023
Three-dimensional histological characterization of the placental vasculature using light sheet microscopy.
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Biomolecules 13
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17 June 2023
Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and development.
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Communications Biology 6
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13 January 2023
c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy.
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Cell Reports 42
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21 March 2023
Cesium activates the neurotransmitter receptor for glycine.
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22 May 2023
Modeling IP(3)-induced Ca(2+) signaling based on its interspike interval statistics.
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11 July 2023
Fiber-orientation independent component of R(2)* obtained from single-orientation MRI measurements in simulations and a post-mortem human optic chiasm.
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25 August 2023
C. elegans gene regulatory alleles and reporter bashing studies.
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Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.
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Nature Communications 14
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4 July 2023
proGenomes3: approaching one million accurately and consistently annotated high-quality prokaryotic genomes.
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6 January 2023
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice.
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Developmental Cell 58
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18 December 2023
Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes.
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Cell Reports 42
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28 February 2023
Treadmill training with virtual reality to enhance gait and cognitive function among people with multiple sclerosis: a randomized controlled trial.
Galperin, I., Mirelman, A., Schmitz-Hübsch, T., Hsieh, K.L., Regev, K., Karni, A., Brozgol, M., Cornejo Thumm, P., Lynch, S.G., Paul, F., Devos, H., Sosnoff, J. and Hausdorff, J.M.
Journal of Neurology 270
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March 2023
Regulation of prostate androgens by megalin and 25-hydroxyvitamin D status: mechanism for high prostate androgens in African American men.
Garcia, J., Krieger, K.D., Loitz, C., Perez, L.M., Richards, Z.A., Helou, Y., Kregel, S., Celada, S., Mesaros, C.A., Bosland, M., Gann, P.H., Willnow, T.E., Vander Griend, D., Kittles, R., Prins, G.S., Penning, T. and Nonn, L.
Cancer Research Communications 3
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3 March 2023
Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and expansion of cTfh1 cells and impaired B memory cell formation.
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Better together: data harmonization and cross-study analysis of abdominal MRI data from UK Biobank and the German National Cohort.
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1 May 2023
Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function.
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Frontiers in Cell and Developmental Biology 11
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7 April 2023
"suMus," a novel digital system for arm movement metrics and muscle energy expenditure.
Gerhalter, Teresa, Müller, Christina, Maron, Elke, Thielen, Markus, Schätzl, Teresa, Mähler, A., Schütte, T., Boschmann, M., Herzer, René, Spuler, S. and Gazzerro, E.
Frontiers in Physiology 14
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26 January 2023
1,2-(13)C(2)-glucose tracing approach to assess metabolic alterations of human monocytes under neuroinflammatory conditions.
Giacomello, G., Otto, C., Priller, J., Ruprecht, K., Böttcher, C. and Parr, M.K.
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16 January 2023
Play and tickling responses map to the lateral columns of the rat periaqueductal gray.
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Neuron 111
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4 October 2023
Internet-delivered cognitive behavioural therapy programme to reduce depressive symptoms in patients with multiple sclerosis: a multicentre, randomised, controlled, phase 3 trial.
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Lancet Digital Health 5
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October 2023
HNF1B alters an evolutionarily conserved nephrogenic program of target genes.
Grand, K., Stoltz, M., Rizzo, L., Röck, R., Kaminski, M.M., Salinas, G., Getwan, M., Naert, T., Pichler, R. and Lienkamp, S.S.
Journal of the American Society of Nephrology 34
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March 2023
A consensus protocol for functional connectivity analysis in the rat brain.
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Nature Neuroscience 26
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April 2023
Personalizing precision medicine: Patients with AML perceptions about treatment decisions.
Grauman, A., Kontro, M., Haller, K., Nier, S., Aakko, S., Lang, K., Zingaretti, C., Meggiolaro, E., De Padova, S., Marconi, G., Martinelli, G., Heckman, C.A., Simonetti, G., Bullinger, L. and Kihlbom, U.
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5 July 2023
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
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Cancer Cell 41
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10 July 2023
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy.
Grosch, M., Schraft, L., Chan, A., Küchenhoff, L., Rapti, K., Ferreira, A.M., Kornienko, J., Li, S., Radke, M.H., Krämer, C., Clauder-Münster, S., Perlas, E., Backs, J., Gotthardt, M., Dieterich, C., van den Hoogenhof, M.M.G., Grimm, D. and Steinmetz, L.M.
Nature Communications 14
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22 June 2023
Multi-site comparison of parametric T1 and T2 mapping: healthy travelling volunteers in the Berlin research network for cardiovascular magnetic resonance (BER-CMR).
Gröschel, J., Trauzeddel, R.F., Müller, M., von Knobelsdorff-Brenkenhoff, F., Viezzer, D., Hadler, T., Blaszczyk, E., Daud, E. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 25
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14 August 2023
Kardiovaskuläre MRT: akute Myokarditis und myokardiale Mitbeteiligung bei Systemerkrankungen.
Gröschel, J.W., Grassow, L., Bhoyroo, Y. and Schulz-Menger, J.
Kardiologie up2date 19
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September 2023
Recombination between heterologous human acrocentric chromosomes.
Guarracino, A., Buonaiuto, S., de Lima, L.G., Potapova, T., Rhie, A., Koren, S., Rubinstein, B., Fischer, C., Gerton, J.L., Phillippy, A.M., Colonna, V. and Garrison, E.
Nature 617
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11 May 2023
Sex-specific microglia state in the neuroligin-4 knock-out mouse model of autism spectrum disorder.
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Brain Behavior and Immunity 111
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Lazy Luna: extendible software for multilevel reader comparison in cardiovascular magnetic resonance imaging.
Hadler, T., Ammann, C., Wetzl, J., Viezzer, D., Gröschel, J., Fenski, M., Abazi, E., Lange, S., Hennemuth, A. and Schulz-Menger, J.
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The effect of brain serotonin deficit (TPH2-KO) on the expression and activity of liver cytochrome P450 enzymes in aging male Dark Agouti rats.
Haduch, A., Bromek, E., Kuban, W., Basińska-Ziobroń, A., Danek, P.J., Alenina, N., Bader, M. and Daniel, W.A.
Pharmacological Reports 75
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December 2023
Hand grip strength in patients with advanced cancer: a prospective study.
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Journal of Cachexia Sarcopenia and Muscle 14
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August 2023
Transcription factor induction of vascular blood stem cell niches in vivo.
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19 June 2023
NCBench: providing an open, reproducible, transparent, adaptable, and continuous benchmark approach for DNA-sequencing-based variant calling.
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F1000Research 12
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11 September 2023
Enhanced biosafety of the Sleeping Beauty transposon system by using mRNA as source of transposase to efficiently and stably transfect retinal pigment epithelial cells.
Harmening, N., Johnen, S., Izsvák, Z., Ivics, Z., Kropp, M., Bascuas, T., Walter, P., Kreis, A., Pajic, B. and Thumann, G.
Biomolecules 13
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7 April 2023
Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis.
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Gut Microbes 15
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Can single-cell and spatial omics unravel the pathophysiology of pre-eclampsia?
Hartmann, S., Botha, S.M., Gray, C.M., Valdes, D.S., Tong, S., Kaitu’u-Lino, T.J., Herse, F., Bergman, L., Cluver, C.A., Dechend, R. and Nonn, O.
Journal of Reproductive Immunology 159
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Seropositivity of Borrelia burgdorferi s.l. in Germany-an analysis across four German National Cohort (NAKO) study sites.
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Scientific Reports 13
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30 November 2023
Analysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort.
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Science Advances 9
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12 May 2023
No secondary treatment failure during incobotulinumtoxin-A long-term treatment demonstrated by the drawing of disease severity.
Hefter, H., Brauns, R., Ürer, B., Rosenthal, D., Albrecht, P. and Samadzadeh, S.
Toxins 15
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12 July 2023
Differences in the time course of recovery from brain and liver dysfunction in conventional long-term treatment of Wilson disease.
Hefter, H., Kruschel, T.S., Novak, M., Rosenthal, D., Luedde, T., Meuth, S.G., Albrecht, P., Hartmann, C.J. and Samadzadeh, S.
Journal of Clinical Medicine 12
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24 July 2023
Significantly lower antigenicity of incobotulinumtoxin than abo- or onabotulinumtoxin.
Hefter, H., Rosenthal, D., Jansen, A., Brauns, R., Ürer, B., Bigalke, H., Hartung, H.P., Meuth, S.G., Lee, J.I., Albrecht, P. and Samadzadeh, S.
Journal of Neurology 270
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February 2023
"Pseudo"-secondary treatment failure explained via disease progression and effective botulinum toxin therapy: a pilot simulation study.
Hefter, H., Rosenthal, D. and Samadzadeh, S.
Toxins 15
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18 October 2023
Exploring the interplay between the clinical and presumed effect of botulinum injections for cervical dystonia: a pilot study.
Hefter, H. and Samadzadeh, S.
Toxins 15
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30 September 2023
Lessons about botulinum toxin A therapy from cervical dystonia patients drawing the course of disease: a pilot study.
Hefter, H., Schomaecker, I., Schomaecker, M., Ürer, B., Brauns, R., Rosenthal, D., Albrecht, P. and Samadzadeh, S.
Toxins 15
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30 June 2023
Autoimmunenzephalitis - ein Update [Autoimmune encephalitis - an update].
Heine, J., Duchow, A., Rust, R., Paul, F., Prüß, H. and Finke, C.
Nervenarzt 94
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June 2023
Structural brain changes in patients with post-COVID fatigue: a prospective observational study.
Heine, J., Schwichtenberg, K., Hartung, T.J., Rekers, S., Chien, C., Boesl, F., Rust, R., Hohenfeld, C., Bungenberg, J., Costa, A.S., Scheibenbogen, C., Bellmann-Strobl, J., Paul, F., Franke, C., Reetz, K. and Finke, C.
EClinicalMedicine 58
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April 2023
A DNA origami-based biointerface to interrogate the spatial requirements for sensitized T-Cell antigen recognition.
Hellmeier, J., Platzer, R., Huppa, J.B. and Sevcsik, E.
Methods in Molecular Biology 2654
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28 April 2023
Generation of two mother-child pairs of iPSCs from maternally inherited Leigh syndrome patients with m.8993 T > G and m.9176 T > G MT-ATP6 mutations.
Henke, M.T., Zink, A., Diecke, S., Prigione, A. and Schuelke, M.
Stem Cell Research 67
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March 2023
Accelerated simultaneous T2 and T2* mapping of multiple sclerosis lesions using compressed sensing reconstruction of radial RARE-EPI MRI.
Herrmann, C.J.J., Starke, L., Millward, J.M., Kuchling, J., Paul, F. and Niendorf, T.
Tomography 9
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31 January 2023
B2 cells contribute to hypertension and natural killer cell activation possibly via AT1-AA in response to placental ischemia.
Herrock, O.T., Deer, E., Amaral, L.M., Campbell, N., Lemon, J., Ingram, N., Cornelius, D.C., Turner, T., Fitzgerald, S., Ibrahim, T., Dechend, R., Wallukat, G. and LaMarca, B.
American Journal of Physiology Renal Physiology 324
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February 2023
Sex-specific stress perfusion cardiac magnetic resonance imaging in suspected ischemic heart disease: insights from SPINS retrospective registry.
Heydari, B., Ge, Y., Antiochos, P., Islam, S., Steel, K., Bingham, S., Abdullah, S., Mikolich, J.R., Arai, A.E., Bandettini, W.P., Patel, A.R., Shanbhag, S.M., Farzaneh-Far, A., Heitner, J.F., Shenoy, C., Leung, S.W., Gonzalez, J.A., Raman, S.V., Ferrari, V.A., Shah, D.J., Schulz-Menger, J., Stuber, M., Simonetti, O.P. and Kwong, R.Y.
JACC: Cardiovascular Imaging 16
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June 2023
3-dimensional strain analysis of hypertrophic cardiomyopathy: insights from the NHLBI International HCM Registry.
Heydari, B., Satriano, A., Jerosch-Herold, M., Kolm, P., Kim, D.Y., Cheng, K., Choi, Y.L., Antiochos, P., White, J.A., Mahmod, M., Chan, K., Raman, B., Desai, M.Y., Ho, C.Y., Dolman, S.F., Desvigne-Nickens, P., Maron, M.S., Friedrich, M.G., Schulz-Menger, J., Piechnik, S.K., Appelbaum, E., Weintraub, W.S., Neubauer, S., Kramer, C.M. and Kwong, R.Y.
JACC: Cardiovascular Imaging 16
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April 2023
SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Heynen, G.J.J.E., Baumgartner, F., Heider, M., Patra, U., Holz, M., Braune, J., Kaiser, M., Schäffer, I., Bamopoulos, S.A., Ramberger, E., Murgai, A., Ng, Y.L.D., Demel, U.M., Laue, D., Liebig, S., Krüger, J., Janz, M., Nogai, A., Schick, M., Mertins, P., Müller, S., Bassermann, F., Krönke, J., Keller, U. and Wirth, M.
Blood Advances 7
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28 February 2023
In vitro fertilization program in white rhinoceros.
Hildebrandt, T.B., Holtze, S., Colleoni, S., Hermes, R., Stejskal, J., Lekolool, I., Ndereeh, D., Omondi, P., Kariuki, L., Mijele, D., Mutisya, S., Ngulu, S., Diecke, S., Hayashi, K., Lazzari, G., de Mori, B., Biasetti, P., Quaggio, A., Galli, C. and Goeritz, F.
Reproduction 166
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25 October 2023
Lung adenocarcinoma promotion by air pollutants.
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Nature 616
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6 April 2023
Die Effekte der Herz-Lungen-Maschine auf das intestinale Mikrobiom und die Relation zum postoperativen SIRS [The effects of the cardiopulmonary bypass on the gut microbiome and its contribution to postoperative SIRS].
Hinkov, H., Markó, L., Nazari-Shafti, T.Z., Neuber, S., Meyborg, H., Krüger, K., Forslund, S.K., Müller, D.N., Falk, V., Emmert, M.Y. and Rodriguez, H.
Zeitschrift fuer Herz-, Thorax- und Gefaesschirurgie 37
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December 2023
The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies.
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July 2023
G(q)-mediated arrhythmogenic signaling promotes atrial fibrillation.
Hohendanner, F., Prabhu, A., Wilck, N., Stangl, V., Pieske, B., Stangl, K. and Althoff, T.F.
Biomedicines 11
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11 February 2023
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
Horkova, V., Drobek, A., Paprckova, D., Niederlova, V., Prasai, A., Uleri, V., Glatzova, D., Kraller, M., Cesnekova, M., Janusova, S., Salyova, E., Tsyklauri, O., Kadlecek, T.A., Krizova, K., Platzer, R., Schober, K., Busch, D.H., Weiss, A., Huppa, J.B. and Stepanek, O.
Nature Immunology 24
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January 2023
A computational map of the human-SARS-CoV-2 protein-RNA interactome predicted at single-nucleotide resolution.
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NAR Genomics and Bioinformatics 5
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March 2023
Single-cell, whole-embryo phenotyping of mammalian developmental disorders.
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Nature 623
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23 November 2023
Radiomics-based aortic flow profile characterization with 4D phase-contrast MRI.
Huellebrand, M., Jarmatz, L., Manini, C., Laube, A., Ivantsits, M., Schulz-Menger, J., Nordmeyer, S., Harloff, A., Hansmann, J., Kelle, S. and Hennemuth, A.
Frontiers in Cardiovascular Medicine 10
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3 April 2023
Grip strength values and cut-off points based on over 200,000 adults of the German National Cohort - a comparison to the EWGSOP2 cut-off points.
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Age and Ageing 52
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January 2023
A hydraulic feedback loop between mesendoderm cell migration and interstitial fluid relocalization promotes embryonic axis formation in zebrafish.
Huljev, K., Shamipour, S., Pinheiro, D., Preusser, F., Steccari, I., Sommer, C.M., Naik, S. and Heisenberg, C.P.
Developmental Cell 58
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10 April 2023
Effects of the COVID-19 pandemic on patients with NMO spectrum disorders and MOG-antibody-associated diseases: COPANMO(G)-Study.
Hümmert, M.W., Bütow, F., Tkachenko, D., Ayzenberg, I., Pakeerathan, T., Hellwig, K., Klotz, L., Häußler, V., Stellmann, J.P., Warnke, C., Goereci, Y., Etgen, T., Luessi, F., Bronzlik, P., Gingele, S., Lauenstein, A.S., Kleiter, I., Rommer, P.S., Paul, F., Bellmann-Strobl, J., Duchow, A., Then Bergh, F., Pul, R., Walter, A., Pellkofer, H., Kümpfel, T., Pompsch, M., Kraemer, M., Albrecht, P., Aktas, O., Ringelstein, M., Senel, M., Giglhuber, K., Berthele, A., Jarius, S., Wildemann, B. and Trebst, C.
Neurology Neuroimmunology & Neuroinflammation 10
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March 2023
Cognition in patients with neuromyelitis optica spectrum disorders: a prospective multicentre study of 217 patients (CogniNMO-Study).
Hümmert, M.W., Stern, C., Paul, F., Duchow, A., Bellmann-Strobl, J., Ayzenberg, I., Schwake, C., Kleiter, I., Hellwig, K., Jarius, S., Wildemann, B., Senel, M., Berthele, A., Giglhuber, K., Luessi, F., Grothe, M., Klotz, L., Schülke, R., Gingele, S., Faiss, J.H., Walter, A., Warnke, C., Then Bergh, F., Aktas, O., Ringelstein, M., Stellmann, J.P., Häußler, V., Havla, J., Pellkofer, H., Kümpfel, T., Kopp, B. and Trebst, C.
Multiple Sclerosis Journal 29
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June 2023
Risk factors and characteristics influencing humoral response to COVID-19 vaccination in patients after allogeneic stem cell transplantation.
Hütter-Krönke, M.L., Neagoie, A., Blau, I.W., Wais, V., Vuong, L., Gantner, A., Ahn, J., Penack, O., Schnell, J., Nogai, K.A., Eberspächer, B., Saadati, M., Benner, A., Bullinger, L., Döhner, H., Bunjes, D. and Sala, E.
Frontiers in Immunology 14
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3 May 2023
Synthetic genetic circuits to uncover the OCT4 trajectories of successful reprogramming of human fibroblasts.
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Science Advances 9
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December 2023
Monitoring mitochondrial translation by pulse SILAC.
Imami, K., Selbach, M. and Ishihama, Y.
Journal of Biological Chemistry 299
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February 2023
Stat1 is an inducible transcriptional repressor of neural stem cells self-renewal program during neuroinflammation.
Imitola, J., Hollingsworth, E.W., Watanabe, F., Olah, M., Elyaman, W., Starossom, S.C., Kivisäkk, P. and Khoury, S.J.
Frontiers in Cellular Neuroscience 17
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16 August 2023
Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors.
Immisch, L., Papafotiou, G., Gallarín Delgado, N., Scheuplein, V., Paschen, A., Blankenstein, T. and Willimsky, G.
Frontiers in Immunology 14
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16 February 2023
Real-world evidence of ocrelizumab-treated relapsing multiple sclerosis cohort shows changes in progression independent of relapse activity mirroring phase 3 trials.
Ingwersen, J., Masanneck, L., Pawlitzki, M., Samadzadeh, S., Weise, M., Aktas, O., Meuth, S.G. and Albrecht, P.
Scientific Reports 13
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11 September 2023
Variable outcomes of hepatitis E infections in patients with hemato-oncologic diseases.
Ingwersen, V., Hofmann, J., Muche, M., Le Coutre, P., Schneider, T., Leng, C., Burmeister, T., Maschmeyer, G., Keller, U. and Schwartz, S.
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August 2023
Disease progression of spinocerebellar ataxia types 1, 2, 3 and 6 before and after ataxia onset.
Jacobi, H., Schaprian, T., Schmitz-Hübsch, T., Schmid, M. and Klockgether, T.
Annals of Clinical and Translational Neurology 10
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October 2023
Clinical impact of the genomic landscape and leukemogenic trajectories in non-intensively treated elderly acute myeloid leukemia patients.
Jahn, E., Saadati, M., Fenaux, P., Gobbi, M., Roboz, G.J., Bullinger, L., Lutsik, P., Riedel, A., Plass, C., Jahn, N., Walter, C., Holzmann, K., Hao, Y., Naim, S., Schreck, N., Krzykalla, J., Benner, A., Keer, H.N., Azab, M., Döhner, K. and Döhner, H.
Leukemia 37
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November 2023
Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice.
Jansch, M., Lubomirov, L.T., Trum, M., Williams, T., Schmitt, J., Schuh, K., Qadri, F., Maier, L.S., Bader, M. and Ritter, O.
FEBS Open Bio 13
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January 2023
Functional analysis of structural variants in single cells using Strand-seq.
Jeong, H., Grimes, K., Rauwolf, K.K., Bruch, P.M., Rausch, T., Hasenfeld, P., Benito, E., Roider, T., Sabarinathan, R., Porubsky, D., Herbst, S.A., Erarslan-Uysal, B., Jann, J.C., Marschall, T., Nowak, D., Bourquin, J.P., Kulozik, A.E., Dietrich, S., Bornhauser, B., Sanders, A.D. and Korbel, J.O.
Nature Biotechnology 41
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June 2023
Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses.
Jiang, B., Schmitt, M.J., Rand, U., Company, C., Dramaretska, Y., Grossmann, M., Serresi, M., Cicin-Sain, L. and Gargiulo, G.
Science Advances 9
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23 June 2023
Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang, Q., Stachelscheid, J., Bloehdorn, J., Pacholewska, A., Aszyk, C.M., Grotenhuijs, F., Müller, T.A., Onder, O., Wagle, P., Herling, C.D., Kleppe, M., Wang, Z., Coombes, K.R., Robrecht, S., Dalvi, P.S., Plosnita, B., Mayer, P., Abruzzo, L.V., Altmüller, J., Gathof, B.S., Persigehl, T., Fischer, K., Jebaraj, B.M.C., Rienhoff, H.Y., Ecker, R.C., Zhao, Y., Bruns, C.J., Stilgenbauer, S., Elenitoba-Johnson, K.S.J., Hallek, M., Schweiger, M.R., Odenthal, M., Vasyutina, E. and Herling, M.
Blood 142
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6 July 2023
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level.
John, L., Poos, A.M., Brobeil, A., Schinke, C., Huhn, S., Prokoph, N., Lutz, R., Wagner, B., Zangari, M., Tirier, S.M., Mallm, J.P., Schumacher, S., Vonficht, D., Solé-Boldo, L., Quick, S., Steiger, S., Przybilla, M.J., Bauer, K., Baumann, A., Hemmer, S., Rehnitz, C., Lückerath, C., Sachpekidis, C., Mechtersheimer, G., Haberkorn, U., Dimitrakopoulou-Strauss, A., Reichert, P., Barlogie, B., Müller-Tidow, C., Goldschmidt, H., Hillengass, J., Rasche, L., Haas, S.F., van Rhee, F., Rippe, K., Raab, M.S., Sauer, S. and Weinhold, N.
Nature Communications 14
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17 August 2023
Small molecule specifically inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation.
Jordan, P., Costa, A., Specker, E., Popp, O., Volkamer, A., Piske, R., Obrusnik, T., Kleissle, S., Stuke, K., Rex, A., Neuenschwander, M., von Kries, J.P., Nazare, M., Mertins, P., Kettenmann, H. and Wolf, S.A.
PLoS ONE 18
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6 February 2023
Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy.
Kalkan, H., Pagano, E., Paris, D., Panza, E., Cuozzo, M., Moriello, C., Piscitelli, F., Abolghasemi, A., Gazzerro, E., Silvestri, C., Capasso, R., Motta, A., Russo, R., Di Marzo, V. and Iannotti, F.A.
EMBO Molecular Medicine 15
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8 March 2023
GRaNIE and GRaNPA: inference and evaluation of enhancer-mediated gene regulatory networks.
Kamal, A., Arnold, C., Claringbould, A., Moussa, R., Servaas, N.H., Kholmatov, M., Daga, N., Nogina, D., Mueller-Dott, S., Reyes-Palomares, A., Palla, G., Sigalova, O., Bunina, D., Pabst, C. and Zaugg, J.B.
Molecular Systems Biology 19
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12 June 2023
Spatially resolved multiomics of human cardiac niches.
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Nature 619
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27 July 2023
Stroke-prone salt-sensitive spontaneously hypertensive rats show higher susceptibility to spreading depolarization (SD) and altered hemodynamic responses to SD.
Kang, E.J., Prager, O., Lublinsky, S., Oliveira-Ferreira, A.I., Reiffurth, C., Major, S., Mueller, D.N., Friedman, A. and Dreier, J.P.
Journal of Cerebral Blood Flow and Metabolism 43
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February 2023
Transgenic rat with overproduction of ubiquitous angiotensin-(1-7) presents neuroprotection in a model of ischemia and reperfusion.
Kangussu, L.M., Almeida-Santos, A.F., Fernandes, L.F., Alenina, N., Bader, M., Santos, R.A.S., Massensini, A.R. and Campagnole-Santos, M.J.
Brain Research Bulletin 192
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January 2023
Postoperative delirium is associated with grey matter brain volume loss.
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Brain Communications 5
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30 January 2023
The effect of renal denervation on T cells in patients with resistant hypertension.
Kantauskaite, M., Vonend, O., Yakoub, M., Heilmann, P., Maifeld, A., Minko, P., Schimmöller, L., Antoch, G., Müller, D.N., Schmidt, C., Duvnjak, B., Zierhut, U., Potthoff, S.A., Rump, L.C., Fischer, J.C. and Stegbauer, J.
International Journal of Molecular Sciences 24
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27 January 2023
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
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Journal of Clinical Investigation 133
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3 April 2023
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx.
Karasaki, T., Moore, D.A., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Magno, N., Ward, S., Bakir, M.A., Watkins, T.B.K., Grigoriadis, K., Huebner, A., Hill, M.S., Frankell, A.M., Abbosh, C., Puttick, C., Zhai, H., Gimeno-Valiente, F., Saghafinia, S., Kanu, N., Dietzen, M., Pich, O., Lim, E.., Martínez-Ruiz, C., Black, J.R.M., Biswas, D., Campbell, B.B., Lee, C., Colliver, E., Enfield, K.S.S., Hessey, S., Hiley, C.T., Zaccaria, S., Litchfield, K., Birkbak, N.J., Cadieux, E.L., Demeulemeester, J., Van Loo, P., Adusumilli, P.S., Tan, K.S., Cheema, W., Sanchez-Vega, F., Jones, D.R., Rekhtman, N., Travis, W.D., Hackshaw, A., Marafioti, T., Salgado, R., Le Quesne, J., Nicholson, A.G., McGranahan, N., Swanton, C. and Jamal-Hanjani, M.
Nature Medicine 29
(4): 833-845.
April 2023
Indications and management of implantable cardioverter-defibrillator therapy in childhood hypertrophic cardiomyopathy.
Kaski, J.P., Kammeraad, J.A.E., Blom, N.A., Happonen, J.M., Janousek, J., Klaassen, S., Limongelli, G., Östman-Smith, I., Sarquella Brugada, G. and Ziolkowska, L.
Cardiology in the Young 33
(5): 681-698.
May 2023
Sputum microbiome and chronic obstructive pulmonary disease in a rural Ugandan cohort of well-controlled HIV infection.
Kayongo, A., Bartolomaeus, T.U.P., Birkner, T., Markó, L., Löber, U., Kigozi, E., Atugonza, C., Munana, R., Mawanda, D., Sekibira, R., Uwimaana, E., Alupo, P., Kalyesubula, R., Knauf, F., Siddharthan, T., Bagaya, B.S., Kateete, D.P., Joloba, M.L., Sewankambo, N.K., Jjingo, D., Kirenga, B., Checkley, W. and Forslund, S.K.
Microbiology Spectrum 11
(2): e0213921.
15 February 2023
(In Press)
Spatiotemporal GPCR signaling illuminated by genetically encoded fluorescent biosensors.
Kayser, C., Melkes, B., Derieux, C. and Bock, A.
Current Opinion in Pharmacology 71
: 102384.
August 2023
Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia.
Kayser, S., Martínez-Cuadrón, D., Rodriguez-Veiga, R., Hänel, M., Tormo, M., Schäfer-Eckart, K., Botella, C., Stölzel, F., Del Castillo, T.B., Keller, U., Rodriguez-Medina, C., Held, G., Amigo, M.L., Schliemann, C., Colorado, M., Kaufmann, M., Garcia, M.B., Krause, S.W., Görner, M., Jost, E., Steffen, B., Zukunft, S., Platzbecker, U., Ho, A.D., Baldus, C.D., Serve, H., Müller-Tidow, C., Thiede, C., Bornhäuser, M., Montesinos, P., Röllig, C. and Schlenk, R.F.
Haematologica 108
(8): 2059-2066.
August 2023
Efficient determination of the accessible conformation space of multi-domain complexes based on EPR PELDOR data.
Kazemi, S., Lopata, A., Kniss, A., Pluska, L., Güntert, P., Sommer, T., Prisner, T.F., Collauto, A. and Dötsch, V.
Journal of Biomolecular NMR 77
(5-6): 261-269.
December 2023
Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Keil, P., Wulf, A., Kachariya, N., Reuscher, S., Hühn, K., Silbern, I., Altmüller, J., Keller, M., Stehle, R., Zarnack, K., Sattler, M., Urlaub, H. and Sträßer, K.
Nucleic Acids Research 51
(2): 831-851.
25 January 2023
IFNγ binding to extracellular matrix prevents fatal systemic toxicity.
Kemna, J., Gout, E., Daniau, L., Lao, J., Weißert, K., Ammann, S., Kühn, R., Richter, M., Molenda, C., Sporbert, A., Zocholl, D., Klopfleisch, R., Schütz, A., Lortat-Jacob, H., Aichele, P., Kammertoens, T. and Blankenstein, T.
Nature Immunology 24
(3): 414-422.
March 2023
Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies.
Kennedy, K.M., de Goffau, M.C., Perez-Muñoz, M.E., Arrieta, M.C., Bäckhed, F., Bork, P., Braun, T., Bushman, F.D., Dore, J., de Vos, W.M., Earl, A.M., Eisen, J.A., Elovitz, M.A., Ganal-Vonarburg, S.C., Gänzle, M.G., Garrett, W.S., Hall, L.J., Hornef, M.W., Huttenhower, C., Konnikova, L., Lebeer, S., Macpherson, A.J., Massey, R.C., McHardy, A.C., Koren, O., Lawley, T.D., Ley, R.E., O'Mahony, L., O'Toole, P.W., Pamer, E.G., Parkhill, J., Raes, J., Rattei, T., Salonen, A., Segal, E., Segata, N., Shanahan, F., Sloboda, D.M., Smith, G.C.S., Sokol, H., Spector, T.D., Surette, M.G., Tannock, G.W., Walker, A.W., Yassour, M. and Walter, J.
Nature 613
(7945): 639-649.
26 January 2023
iPSC-derived reactive astrocytes from patients with multiple-sclerosis protect cocultured neurons in inflammatory conditions.
Kerkering, J., Muinjonov, B., Rosiewicz, K.S., Diecke, S., Biese, C., Schiweck, J., Chien, C., Zocholl, D., Conrad, T., Paul, F., Alisch, M. and Siffrin, V.
Journal of Clinical Investigation 133
(13): e164637.
3 July 2023
Motion-corrected model-based reconstruction for 2D myocardial T1 mapping.
Kerkering, K.M., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Magnetic Resonance in Medicine 90
(3): 1086-1100.
September 2023
Discrimination of multiple sclerosis using OCT images from two different centers.
Khodabandeh, Z., Rabbani, H., Ashtari, F., Zimmermann, H.G., Motamedi, S., Brandt, A.U., Paul, F. and Kafieh, R.
Multiple Sclerosis and Related Disorders 77
: 104846.
September 2023
Osteopontin is a prognostic circulating biomarker in patients with neuroendocrine neoplasms.
Kidess, E., Giesecke, Y., Eichhorn, I., Mohr, R., Jann, H., Fischer, C., Wiedenmann, B., Roderburg, C., Tacke, F. and Sigal, M.
Journal of Cancer Research and Clinical Oncology 149
(12): 10925-10933.
September 2023
Inebilizumab reduces neuromyelitis optica spectrum disorder risk independent of FCGR3A polymorphism.
Kim, H.J., Aktas, O., Patterson, K.R., Korff, S., Kunchok, A., Bennett, J.L., Weinshenker, B.G., Paul, F., Hartung, H.P., Cimbora, D., Smith, M.A., Mittereder, N., Rees, W.A., She, D. and Cree, B.A.C.
Annals of Clinical and Translational Neurology 10
(12): 2413-2420.
December 2023
Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies.
Kleo, K., Jovanovic, V.M., Arndold, A., Lehmann, A., Lammert, H., Berg, E., Harloff, H., Treese, C., Hummel, M. and Daum, S.
Journal of Cancer Research and Clinical Oncology 149
(3): 1049-1061.
March 2023
AML with complex karyotype: extreme genomic complexity revealed by combined long-read sequencing and Hi-C technology.
Klever, M.K., Sträng, E., Hetzel, S., Jungnitsch, J., Dolnik, A., Schöpflin, R., Schrezenmeier, J.F.F., Schick, F., Blau, O., Westermann, J., Rücker, F.G., Xia, Z., Döhner, K., Schrezenmeier, H., Spielmann, M., Meissner, A., Melo, U.S., Mundlos, S. and Bullinger, L.
Blood Advances 7
(21): 6520-6531.
14 November 2023
Mutations in plasticity-related-gene-1 (PRG-1) protein contribute to hippocampal seizure susceptibility and modify epileptic phenotype.
Knierim, E., Vogt, J., Kintscher, M., Ponomarenko, A., Baumgart, J., Beed, P., Korotkova, T., Trimbuch, T., Panzer, A., Steinlein, O.K., Stephani, U., Escayg, A., Koko, M., Liu, Y., Lerche, H., Schmitz, D., Nitsch, R. and Schuelke, M.
Cerebral Cortex 33
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15 June 2023
Identification of drug candidates targeting monocyte reprogramming in people living with HIV.
Knoll, R., Bonaguro, L., Dos Santos, J.C., Warnat-Herresthal, S., Jacobs-Cleophas, M.C.P., Blümel, E., Reusch, N., Horne, A., Herbert, M., Nuesch-Germano, M., Otten, T., van der Heijden, W.A., van de Wijer, L., Shalek, A.K., Händler, K., Becker, M., Beyer, M.D., Netea, M.G., Joosten, L.A.B., van der Ven, A.J.A.M., Schultze, J.L. and Aschenbrenner, A.C.
Frontiers in Immunology 14
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20 November 2023
Resilience and stability of the CF- intestinal and respiratory microbiome during nutritional and exercise intervention.
Knoll, R.L., Jarquín-Díaz, V.H., Klopp, J., Kemper, A., Hilbert, K., Hillen, B., Pfirrmann, D., Simon, P., Bähner, V., Nitsche, O., Gehring, S., Markó, L., Forslund, S.K. and Poplawska, K.
BMC Microbiology 23
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21 February 2023
PI3K-C2β limits mTORC1 signaling and angiogenic growth.
Kobialka, P., Llena, J., Deleyto-Seldas, N., Munar-Gelabert, M., Dengra, J.A., Villacampa, P., Albinyà-Pedrós, A., Muixi, L., Andrade, J., van Splunder, H., Angulo-Urarte, A., Potente, M., Grego-Bessa, J., Castillo, S.D., Vanhaesebroeck, B., Efeyan, A. and Graupera, M.
Science Signaling 16
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November 2023
Immunomodulatory effects of new phenanthrene derivatives from Dendrobium crumenatum.
Kongkatitham, V., Dehlinger, A., Wang, M., Poldorn, P., Weidinger, C., Letizia, M., Chaotham, C., Otto, C., Ruprecht, K., Paul, F., Rungrotmongkol, T., Likhitwitayawuid, K., Böttcher, C. and Sritularak, B.
Journal of Natural Products 86
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26 May 2023
Resolving crosstalk between signaling pathways using mathematical modeling and time-resolved single cell data.
Konrath, F., Loewer, A. and Wolf, J.
Methods in Molecular Biology 2634
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2023
A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1.
Konrath, F., Willenbrock, M., Busse, D., Scheidereit, C. and Wolf, J.
iScience 26
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20 October 2023
Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3.
Kornienko, J., Rodríguez-Martínez, M., Fenzl, K., Hinze, F., Schraivogel, D., Grosch, M., Tunaj, B., Lindenhofer, D., Schraft, L., Kueblbeck, M., Smith, E., Mao, C., Brown, E., Owens, A., Saguner, A.M., Meder, B., Parikh, V., Gotthardt, M. and Steinmetz, L.M.
Nature Communications 14
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18 July 2023
Studies in zebrafish and rat models support dual blockade of EP2 and EP4 (prostaglandin E(2) receptors type 2 and 4) for renoprotection in glomerular hyperfiltration and albuminuria.
Kourpa, A., Schulz, A., Mangelsen, E., Kaiser-Graf, D., Koppers, N., Stoll, M., Rothe, M., Bader, M., Purfürst, B., Kunz, S., Gladytz, T., Niendorf, T., Bachmann, S., Mutig, K., Bolbrinker, J., Panakova, D. and Kreutz, R.
Hypertension 80
(4): 771-782.
April 2023
Influence of phosphorylation on intermediate filaments.
Kraxner, J. and Köster, S.
Biological Chemistry 404
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20 April 2023
Preclinical safety and efficacy of a therapeutic antibody that targets SARS-CoV-2 at the sotrovimab face but is escaped by Omicron.
Kreye, J., Reincke, S.M., Edelburg, S., Jeworowski, L.M., Kornau, H.C., Trimpert, J., Hombach, P., Halbe, S., Nölle, V., Meyer, M., Kattenbach, S., Sánchez-Sendin, E., Schmidt, M.L., Schwarz, T., Rose, R., Krumbholz, A., Merz, S., Adler, J.M., Eschke, K., Abdelgawad, A., Schmitz, D., Sander, L.E., Janssen, U., Corman, V.M. and Prüss, H.
iScience 26
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21 April 2023
Synchrones Auftreten eines Adenokarzinoms und eines Non-Hodgkin B-Zell-Lymphoms bei einem Patienten mit einem variablen Immundefektsyndrom (CVID) [When malignancy hits twice - synchronous gastric carcinoma and non-Hodgkin-B-cell lymphoma in a patient with common variable immunodeficiency].
Krick, D., Hauptmann, K., Penndorf, V., Tacke, F., Krüger, R., von Bernuth, H. and Sigal, M.
Zeitschrift fur Gastroenterologie 61
(7): 827-831.
July 2023
Rapid estimation of 2D relative B(1)(+)-maps from localizers in the human heart at 7T using deep learning.
Krueger, F., Aigner, C.S., Hammernik, K., Dietrich, S., Lutz, M., Schulz-Menger, J., Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 89
(6): 1002-1015.
March 2023
Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia.
Kuhrt, L.D., Motta, E., Elmadany, N., Weidling, H., Fritsche-Guenther, R., Efe, I.E., Cobb, O., Chatterjee, J., Boggs, L.G., Schnauß, M., Diecke, S., Semtner, M., Anastasaki, C., Gutmann, D.H. and Kettenmann, H.
Disease Models & Mechanisms 16
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December 2023
Disruption of stem cell niche-confined R-spondin 3 expression leads to impaired hematopoiesis.
Kurtova, A.V., Heinlein, M., Haas, S., Velten, L., Dijkgraaf, G.J.P., Storm, E.E., Kljavin, N.M., Boumahdi, S., Himmels, P., Herault, A., Mancini, A.G., Koeppen, H., Dail, M., Yan, M., Zhang, J., Koch, U., Radtke, F., Modrusan, Z., Metcalfe, C., Piskol, R. and de Sauvage, F.J.
Blood Advances 7
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28 February 2023
Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch, J., Theisen, S., Dartsch, J., Fritsche-Guenther, R., Kirchner, M., Obermayer, B., Bauer, A., Kahlert, A.K., Rothe, M., Beule, D., Heuser, A., Mertins, P., Kirwan, J.A., Berndt, N., MacRae, C.A., Hubner, N. and Klaassen, S.
Cardiovascular Research 119
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December 2023
Visualizing MyoD oscillations in muscle stem cells.
Lahmann, I. and Birchmeier, C.
Methods in Molecular Biology 2640
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2023
Enterotypes of the human gut mycobiome.
Lai, S., Yan, Y., Pu, Y., Lin, S., Qiu, J.G., Jiang, B.H., Keller, M.I., Wang, M., Bork, P., Chen, W.H., Zheng, Y. and Zhao, X.M.
Microbiome 11
(1): 179.
11 August 2023
Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.
Lareau, C.A., Dubois, S.M., Buquicchio, F.A., Hsieh, Y.H., Garg, K., Kautz, P., Nitsch, L., Praktiknjo, S.D., Maschmeyer, P., Verboon, J.M., Gutierrez, J.C., Yin, Y., Fiskin, E., Luo, W., Mimitou, E.P., Muus, C., Malhotra, R., Parikh, S., Fleming, M.D., Oevermann, L., Schulte, J., Eckert, C., Kundaje, A., Smibert, P., Vardhana, S.A., Satpathy, A.T., Regev, A., Sankaran, V.G., Agarwal, S. and Ludwig, L.S.
Nature Genetics 55
(7): 1198-1209.
July 2023
Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility.
Lareau, C.A., Liu, V., Muus, C., Praktiknjo, S.D., Nitsch, L., Kautz, P., Sandor, K., Yin, Y., Gutierrez, J.C., Pelka, K., Satpathy, A.T., Regev, A., Sankaran, V.G. and Ludwig, L.S.
Nature Protocols 18
(5): 1416-1440.
May 2023
Latent human herpesvirus 6 is reactivated in CAR T cells.
Lareau, C.A., Yin, Y., Maurer, K., Sandor, K.D., Daniel, B., Yagnik, G., Peña, J., Crawford, J.C., Spanjaart, A.M., Gutierrez, J.C., Haradhvala, N.J., Riberdy, J.M., Abay, T., Stickels, R.R., Verboon, J.M., Liu, V., Buquicchio, F.A., Wang, F., Southard, J., Song, R., Li, W., Shrestha, A., Parida, L., Getz, G., Maus, M.V., Li, S., Moore, A., Roberts, Z.J., Ludwig, L.S., Talleur, A.C., Thomas, P.G., Dehghani, H., Pertel, T., Kundaje, A., Gottschalk, S., Roth, T.L., Kersten, M.J., Wu, C.J., Majzner, R.G. and Satpathy, A.T.
Nature 623
: 608-615.
16 November 2023
Discriminating promiscuous from target-specific autoantibodies in COVID-19.
Lebedin, M., Vazquez Garcia, C., Spatt, L., Ratswohl, C., Thibeault, C., Ostendorf, L., Alexander, T., Paul, F., Sander, L.E., Kurth, F. and de la Rosa, K.
European Journal of Immunology 53
(5): e2250210.
May 2023
Pan-conserved segment tags identify ultra-conserved sequences across assemblies in the human pangenome.
Lee, H., Greer, S.U., Pavlichin, D.S., Zhou, B., Urban, A.E., Weissman, T. and Ji, H.P.
Cell Reports Methods 3
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28 August 2023
Long-term symptom severity and clinical biomarkers in post-COVID-19/chronic fatigue syndrome: results from a prospective observational cohort.
Legler, F., Meyer-Arndt, L., Mödl, L., Kedor, C., Freitag, H., Stein, E., Hoppmann, U., Rust, R., Wittke, K., Siebert, N., Behrens, J., Thiel, A., Konietschke, F., Paul, F., Scheibenbogen, C. and Bellmann-Strobl, J.
EClinicalMedicine 63
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19 August 2023
Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini, I., Emmenegger, L., Zappulo, A., Rybak-Wolf, A., Wurmus, R., Oliveras Martinez, A., Cerda Jara, C., Boltengagen, A., Hessler, T., Mastrobuoni, G., Kempa, S., Zinzen, R., Woehler, A. and Rajewsky, N.
Nature Methods 20
(10): 1544-1552.
October 2023
Clinical and prognostic relevance of cardiac wasting in patients with advanced cancer.
Lena, A., Wilkenshoff, U., Hadzibegovic, S., Porthun, J., Rösnick, L., Fröhlich, A.K., Zeller, T., Karakas, M., Keller, U., Ahn, J., Bullinger, L., Riess, H., Rosen, S.D., Lyon, A.R., Lüscher, T.F., Totzeck, M., Rassaf, T., Burkhoff, D., Mehra, M.R., Bax, J.J., Butler, J., Edelmann, F., Haverkamp, W., Anker, S.D., Packer, M., Coats, A.J.S., von Haehling, S., Landmesser, U. and Anker, M.S.
Journal of the American College of Cardiology 81
(16): 1569-1586.
25 April 2023
Hepatobiliary long-term consequences of COVID-19: dramatically increased rate of secondary sclerosing cholangitis in critically ill COVID-19 patients.
Leonhardt, S., Jürgensen, C., Frohme, J., Grajecki, D., Adler, A., Sigal, M., Leonhardt, J., Voll, J.M., Kruse, J.M., Körner, R., Eckardt, K.U., Janssen, H.J., Gebhardt, V., Schmittner, M.D., Frey, C., Müller-Ide, H., Bauer, M., Thibeault, C., Kurth, F., Sander, L.E., Müller, T. and Tacke, F.
Hepatology International 17
(6): 1610-1625.
December 2023
Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.
Li, B., Zeis, P., Zhang, Y., Alekseenko, A., Fürst, E., Sanchez, Y.P., Lin, G., Tekkedil, M.M., Piazza, I., Steinmetz, L.M. and Pelechano, V.
Nature Communications 14
(1): 910.
17 February 2023
Angiotensin receptor-neprilysin inhibitor improves coronary collateral perfusion.
Li, K., Kratzmann, V., Dai, M., Gatzke, N., Rocic, P., Bramlage, P., Grisk, O., Lubomirov, L.T., Hoffmeister, M., Lauxmann, M.A., Ritter, O., Buschmann, E., Bader, M., Persson, A.B., Buschmann, I. and Hillmeister, P.
Frontiers in Cardiovascular Medicine 9
: 981333.
3 February 2023
Brain blood vessel autoantibodies in patients with NMDA and GABAA receptor encephalitis: identification of unconventional Myosin-X as target antigen.
Li, L.Y., Kreye, J., Burek, M., Cordero-Gomez, C., Barthel, P.C., Sánchez-Sendín, E., Kornau, H.C., Schmitz, D., Scharf, M., Meybohm, P., Reincke, S.M., Prüss, H. and Höltje, M.
Frontiers in Cellular Neuroscience 17
30 January 2023
A weak-labelling and deep learning approach for in-focus object segmentation in 3D widefield microscopy.
Li, R., Kudryashev, M. and Yakimovich, A.
Scientific Reports 13
(1): 12275.
28 July 2023
Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2.
Li, R., Shao, J., Jin, Y.J., Kawase, H., Ong, Y.T., Troidl, K., Quan, Q., Wang, L., Bonnavion, R., Wietelmann, A., Helmbacher, F., Potente, M., Graumann, J., Wettschureck, N. and Offermanns, S.
Nature Communications 14
(1): 1980.
8 April 2023
Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Li, X., Wu, F., Günther, S., Looso, M., Kuenne, C., Zhang, T., Wiesnet, M., Klatt, S., Zukunft, S., Fleming, I., Poschet, G., Wietelmann, A., Atzberger, A., Potente, M., Yuan, X. and Braun, T.
Nature 622
(7983): 619-626.
19 October 2023
SPSB1-mediated inhibition of TGF-β receptor-II impairs myogenesis in inflammation.
Li, Y., Dörmann, N., Brinschwitz, B., Kny, M., Martin, E., Bartels, K., Li, N., Giri, P.V., Schwanz, S., Boschmann, M., Hille, S., Fielitz, B., Wollersheim, T., Grunow, J., Felix, S.B., Weber-Carstens, S., Luft, F.C., Müller, O.J. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 14
(4): 1721-1736.
August 2023
Combining in vivo proton exchange rate (k(ex)) MRI with quantitative susceptibility mapping to further stratify the gadolinium-negative multiple sclerosis lesions.
Liao, H., Cai, Z., Ye, H., Chen, Q.L., Zhang, Y., Shaghaghi, M., Lutz, S.E., Chen, W. and Cai, K.
Frontiers in Neuroscience 16
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11 January 2023
A draft human pangenome reference.
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Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
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Investigating people’s attitudes towards participating in longitudinal health research: an intersectionality-informed perspective.
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Inflammatory cytokines associated with multiple sclerosis directly induce alterations of neuronal cytoarchitecture in human neurons.
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Journal of Neuroimmune Pharmacology 18
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June 2023
Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection.
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25 September 2023
Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.
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Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence.
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CRISPR/Cas9 screen in gastric cancer patient-derived organoids reveals KDM1A-NDRG1 axis as a targetable vulnerability.
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Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
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Nature Communications 14
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6 January 2023
Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis.
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Nature Communications 14
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11 February 2023
CLK2 and CLK4 are regulators of DNA damage-induced NF-κB targeted by novel small molecule inhibitors.
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19 October 2023
Early myocardial oedema can predict subsequent cardiomyopathy in high-dose anthracycline therapy.
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Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development.
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Bringing MRI to low- and middle-income countries: Directions, challenges and potential solutions.
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July 2023
The Berlin-Buch respiration chamber for energy expenditure measurements.
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5 April 2023
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Cas9-induced single cut enables highly efficient and template-free repair of a muscular dystrophy causing founder mutation.
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Linoleic acid potentiates CD8(+) T cell metabolic fitness and antitumor immunity.
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Cell Metabolism 35
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4 April 2023
Role of TMEM100 in mechanically insensitive nociceptor un-silencing.
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Nature Communications 14
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A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation.
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10 February 2023
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
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20 April 2023
C/EBPβ-induced lymphoid-to-myeloid transdifferentiation emulates granulocyte-monocyte progenitor biology.
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Stem Cell Reports 19
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28 December 2023
SODAR: managing multiomics study data and metadata.
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27 July 2023
Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver.
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Nature Aging 3
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November 2023
Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer.
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BMC Medicine 21
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13 October 2023
Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root.
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Maternal COVID-19 causing intrauterine foetal demise with microthrombotic placental insufficiency: a case report.
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Disease- and sex-specific differences in patients with heart valve disease: a proteome study.
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March 2023
Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters.
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Nature Microbiology 8
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May 2023
Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.
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12 October 2023
Radiofrequency antenna concepts for human cardiac MR at 14.0 T.
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Magnetic Resonance Materials in Physics Biology and Medicine 36
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April 2023
Single-cell clonal tracking of persistent T-cells in allogeneic hematopoietic stem cell transplantation.
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Frontiers in Immunology 14
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10 February 2023
Modeling of ACTN4-based podocytopathy using Drosophila nephrocytes.
Odenthal, J., Dittrich, S., Ludwig, V., Merz, T., Reitmeier, K., Reusch, B., Höhne, M., Cosgun, Z.C., Hohenadel, M., Putnik, J., Göbel, H., Rinschen, M.M., Altmüller, J., Koehler, S., Schermer, B., Benzing, T., Beck, B.B., Brinkkötter, P.T., Habbig, S. and Bartram, M.P.
Kidney International Reports 8
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February 2023
Visually evoked potential as prognostic biomarker for neuroaxonal damage in multiple sclerosis from a multicenter longitudinal cohort.
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Neurology Neuroimmunology & Neuroinflammation 10
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May 2023
Diagnostic value of intereye difference metrics for optic neuritis in aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorders.
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Journal of Neurology, Neurosurgery, and Psychiatry 94
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July 2023
Daratumumab for the treatment of refractory ANCA-associated vasculitis.
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10 January 2023
Maternal haemodynamics in Hypertensive Disorders of Pregnancy under antihypertensive therapy (HyperDiP): study protocol for a prospective observational case-control study.
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BMJ Open 13
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June 2023
Gut microbiome and atrial fibrillation - results from a large population-based study.
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Clinical implications and dynamics of clonal hematopoiesis in anti-CD19 CAR T-cell treated patients.
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HemaSphere 7
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October 2023
MDC1 maintains active elongation complexes of RNA polymerase II.
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Cell Reports 42
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31 January 2023
International delphi consensus on the management of AQP4-IgG+ NMOSD: recommendations for eculizumab, inebilizumab, and satralizumab.
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Neurology Neuroimmunology & Neuroinflammation 10
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July 2023
Galectin-3 interacts with PD-1 and counteracts the PD-1 pathway-driven regulation of T cell and osteoclast activity in Rheumatoid Arthritis.
Pedersen, K., Nielsen, M.A., Juul-Madsen, K., Hvid, M., Deleuran, B. and Greisen, S.R.
Scandinavian Journal of Immunology 97
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February 2023
Functional assay for assessment of agonistic or antagonistic activity of angiotensin AT(2) receptor ligands reveals that EMA401 and PD123319 have agonistic properties.
Peluso, A.A., Souza Silva, I.M., Villela, D.C., Hansen, P.B.L., Hallberg, A., Bader, M., Santos, R., Sumners, C. and Muscha Steckelings, U.
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Protocol to dissociate healthy and infected murine- and hamster-derived lung tissue for single-cell transcriptome analysis.
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17 March 2023
Mitochondrial DNA mutations as natural barcodes for lineage tracing of murine tumor models.
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1 March 2023
Using PrISMa to reveal the interactome of the human claudins family.
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15 December 2023
Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D.
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Proceedings of the National Academy of Sciences of the United States of America 120
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24 January 2023
SLC26A1 is a major determinant of sulfate homeostasis in humans.
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Journal of Clinical Investigation 133
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1 February 2023
Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study.
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Journal of Cancer Research and Clinical Oncology 149
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November 2023
H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma.
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December 2023
Estimation of migraine prevalence considering active and inactive states across different age groups.
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Journal of Headache and Pain 24
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11 July 2023
Ravulizumab in aquaporin-4-positive neuromyelitis optica spectrum disorder.
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Annals of Neurology 93
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June 2023
Multiple sclerosis and circadian rhythms: Can diet act as a treatment?
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Acta Physiologica 237
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April 2023
Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion.
Platzer, R., Hellmeier, J., Göhring, J., Perez, I.D., Schatzlmaier, P., Bodner, C., Focke-Tejkl, M., Schütz, G.J., Sevcsik, E., Stockinger, H., Brameshuber, M. and Huppa, J.B.
EMBO Reports 24
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6 November 2023
The rate of spontaneous mutations in yeast deficient for MutSβ function.
Plavskin, Y., de Biase, M.S., Schwarz, R.F. and Siegal, M.L.
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March 2023
Generation of TGFβR2(-1) neoantigen-specific HLA-DR4-restricted T cell receptors for cancer therapy.
Plewa, N., Poncette, L. and Blankenstein, T.
Journal for ImmunoTherapy of Cancer 11
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February 2023
Cox proportional hazards deep neural network identifies peripheral blood complete remission to be at least equivalent to morphologic complete remission in predicting outcomes of patients treated with azacitidine - a prospective cohort study by the AGMT.
Pleyer, L., Vaisband, M., Drost, M., Pfeilstöcker, M., Stauder, R., Heibl, S., Sill, H., Girschikofsky, M., Stampfl-Mattersberger, M., Pichler, A., Hartmann, B., Petzer, A., Schreder, M., Schmitt, C.A., Vallet, S., Melchardt, T., Zebisch, A., Pichler, P., Zaborsky, N., Machherndl-Spandl, S., Wolf, D., Keil, F., Hasenauer, J., Larcher-Senn, J. and Greil, R.
American Journal of Hematology 98
(11): 1685-1698.
November 2023
Inversion polymorphism in a complete human genome assembly.
Porubsky, D., Harvey, W.T., Rozanski, A.N., Ebler, J., Höps, W., Ashraf, H., Hasenfeld, P., Paten, B., Sanders, A.D., Marschall, T., Korbel, J.O. and Eichler, E.E.
Genome Biology 24
(1): 100.
30 April 2023
Gaps and complex structurally variant loci in phased genome assemblies.
Porubsky, D., Vollger, M.R., Harvey, W.T., Rozanski, A.N., Ebert, P., Hickey, G., Hasenfeld, P., Sanders, A.D., Stober, C., Korbel, J.O., Paten, B., Marschall, T. and Eichler, E.E.
Genome Research 33
(4): 496-510.
April 2023
What can Ribo-seq, immunopeptidomics, and proteomics tell us about the non-canonical proteome?
Prensner, J.R., Abelin, J.G., Kok, L.W., Clauser, K.R., Mudge, J.M., Ruiz-Orera, J., Bassani-Sternberg, M., Moritz, R.L., Deutsch, E.W. and van Heesch, S.
Molecular & Cellular Proteomics 22
(9): 100631.
September 2023
Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.
Proft, S., Leiz, J., Heinemann, U., Seelow, D., Schmidt-Ott, K.M. and Rutkiewicz, M.
BMC Genomics 24
(1): 736.
4 December 2023
Cryo-EM captures early ribosome assembly in action.
Qin, B., Lauer, S.M., Balke, A., Vieira-Vieira, C.H., Bürger, J., Mielke, T., Selbach, M., Scheerer, P., Spahn, C.M.T. and Nikolay, R.
Nature Communications 14
(1): 898.
17 February 2023
Retrotransposon: a versatile player in human preimplantation development and health.
Qu, Y., Izsvák, Z. and Wang, J.
Life Medicine 2
(1): 1-3.
February 2023
LINC01013 is a determinant of fibroblast activation and encodes a novel fibroblast-activating micropeptide.
Quaife, N.M., Chothani, S., Schulz, J.F., Lindberg, E.L., Vanezis, K., Adami, E., O'Fee, K., Greiner, J., Litviňuková, M., van Heesch, S., Whiffin, N., Hubner, N., Schafer, S., Rackham, O., Cook, S.A. and Barton, P.J.R.
Journal of cardiovascular translational research 16
(1): 77-85.
February 2023
Visualization and data exploration of chromosome conformation capture data using Voronoi diagrams with v3c-viz.
Race, A.M., Fuchs, A. and Chung, H.R.
Scientific Reports 13
(1): 22020.
12 December 2023
Microglia actively remove NR1 autoantibody-bound NMDA receptors and associated post-synaptic proteins in neuron microglia co-cultures.
Rahman, K.A., Orlando, M., Boulos, A., Andrzejak, E., Schmitz, D., Ziv, N.E., Prüss, H., Garner, C.C. and Ichkova, A.
Glia 71
(8): 1804-1829.
August 2023
An integrate-and-fire approach to Ca(2+) signaling. Part II: Cumulative refractoriness.
Ramlow, L., Falcke, M. and Lindner, B.
Biophysical Journal 122
(24): 4710-4729.
19 December 2023
An integrate-and-fire approach to Ca(2+) signaling. Part I: Renewal model.
Ramlow, L., Falcke, M. and Lindner, B.
Biophysical Journal 122
(4): 713-736.
21 February 2023
Comparable in vivo joint kinematics between self-reported stable and unstable knees after TKA can be explained by muscular adaptation strategies: a retrospective observational study.
Rao, L., Horn, N., Meister, N., Preiss, S., Taylor, W.R., Santuz, A. and Schütz, P.
eLife 12
: e85136.
26 April 2023
A design strategy to generate a SARS-CoV-2 RBD vaccine that abrogates ACE2 binding and improves neutralizing antibody responses.
Ratswohl, C., Vázquez García, C., Ahmad, A.U.W., Gonschior, H., Lebedin, M., Silvis, C.E., Spatt, L., Gerhard, C., Lehmann, M., Sander, L.E., Kurth, F., Olsson, S. and de la Rosa, K.
European Journal of Immunology 53
(10): e2350408.
October 2023
Treatment of infants and children with SARS-CoV-2 monoclonal antibodies: a European case series.
Rau, C., Auer-Hackenberg, L., Deubzer, H.E., Schwabel, E., Jaros, M., Diederichs, A., Lehrnbecher, T., Holm, M., von Linstow, M.L., Martin, L., Dinges, S.S., Rothensteiner, M., Siepermann, M., Strenger, V., von Both, U., Teig, N., Brinkmann, F., Leeb, F., Zeitlinger, M., Kobbe, R. and Götzinger, F.
Pediatric Infectious Disease Journal 42
(2): 125-129.
February 2023
Long-read sequencing of diagnosis and post-therapy medulloblastoma reveals complex rearrangement patterns and epigenetic signatures.
Rausch, T., Snajder, R., Leger, A., Simovic, M., Giurgiu, M., Villacorta, L., Henssen, A.G., Fröhling, S., Stegle, O., Birney, E., Bonder, M.J., Ernst, A. and Korbel, J.O.
Cell Genomics 3
(4): 100281.
12 April 2023
Cell adhesion and immune response, two main functions altered in the transcriptome of seasonally regressed testes of two mammalian species.
Real, F.M., Lao-Pérez, M., Burgos, M., Mundlos, S., Lupiáñez, D.G., Jiménez, R. and Barrionuevo, F.J.
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 340
(3): 231-244.
May 2023
Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells.
Reincke, S.M., von Wardenburg, N., Homeyer, M.A., Kornau, H.C., Spagni, G., Li, L.Y., Kreye, J., Sánchez-Sendín, E., Blumenau, S., Stappert, D., Radbruch, H., Hauser, A.E., Künkele, A., Edes, I., Schmitz, D. and Prüss, H.
Cell 186
(23): 5084-5097.e18.
9 November 2023
Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion.
Rejeski, K., Perez, A., Iacoboni, G., Blumenberg, V., Bücklein, V.L., Völkl, S., Penack, O., Albanyan, O., Stock, S., Müller, F., Karschnia, P., Petrera, A., Reid, K., Faramand, R., Davila, M.L., Modi, K., Dean, E.A., Bachmeier, C., von Bergwelt-Baildon, M., Locke, F.L., Bethge, W., Bullinger, L., Mackensen, A., Barba, P., Jain, M.D. and Subklewe, M.
Science Advances 9
(38): eadg3919.
22 September 2023
Translating principles of quality control to cardiovascular magnetic resonance: assessing quantitative parameters of the left ventricle in a large cohort.
Riazy, L., Däuber, S., Lange, S., Viezzer, D.S., Ott, S., Wiesemann, S., Blaszczyk, E., Mühlberg, F., Zange, L. and Schulz-Menger, J.
Scientific Reports 13
(1): 2205.
7 February 2023
Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Richter, F.C., Friedrich, M., Kampschulte, N., Piletic, K., Alsaleh, G., Zummach, R., Hecker, J., Pohin, M., Ilott, N., Guschina, I., Wideman, S.K., Johnson, E., Borsa, M., Hahn, P., Morriseau, C., Hammock, B.D., Schipper, H.S., Edwards, C.M, Zechner, R., Siegmund, B., Weidinger, C., Schebb, N.H., Powrie, F. and Simon, A.K.
EMBO Journal 42
(6): e112202.
15 March 2023
Time-to-care metrics in patients with interhospital transfer for mechanical thrombectomy in north-east Germany: primary telestroke centers in rural areas vs. primary stroke centers in a metropolitan area.
Riegler, C., Behrens, J.R., Gorski, C., Angermaier, A., Kinze, S., Ganeshan, R., Rocco, A., Kunz, A., Müller, T.J., Bitsch, A., Grüger, A., Weber, J.E., Siebert, E., Bollweg, K., von Rennenberg, R., Audebert, H.J., Nolte, C.H. and Erdur, H.
Frontiers in Neurology 13
: 1046564.
9 January 2023
Targeted treatment in a case series of AR+, HRAS/PIK3CA co-mutated salivary duct carcinoma.
Rieke, D.T., Schröder, S., Schafhausen, P., Blanc, E., Zuljan, E., von der Emde, B., Beule, D., Keller, U., Keilholz, U. and Klinghammer, K.
Frontiers in Oncology 13
: 1107134.
2023
Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly.
Rizalar, F.S., Lucht, M.T., Petzoldt, A., Kong, S., Sun, J., Vines, J.H., Telugu, N.S., Diecke, S., Kaas, T., Bullmann, T., Schmied, C., Löwe, D., King, J.S., Cho, W., Hallermann, S., Puchkov, D., Sigrist, S.J. and Haucke, V.
Science 382
(6667): 223-230.
12 October 2023
Angiotensin deficient FVB/N mice are normotensive.
Rodrigues, A.F., Todiras, M., Qadri, F., Alenina, N. and Bader, M.
British Journal of Pharmacology 180
(14): 1843-1861.
July 2023
Mutational topography reflects clinical neuroblastoma heterogeneity.
Rodriguez-Fos, E., Planas-Fèlix, M., Burkert, M., Puiggròs, M., Toedling, J., Thiessen, N., Blanc, E., Szymansky, A., Hertwig, F., Ishaque, N., Beule, D., Torrents, D., Eggert, A., Koche, R.P., Schwarz, R.F., Haase, K., Schulte, J.H. and Henssen, A.G.
Cell Genomics 3
(10): 100402.
11 October 2023
Update Curriculum Kardiale Magnetresonanztomographie [Update on the cardiac magnetic resonance imaging curriculum].
Rolf, A., Eitel, I., Neizel-Wittke, M., Radunski, U.K., Bernhardt, P., von Knobelsdorff, F., André, F., Nagel, E., Schulz-Menger, J. and Kelle, S.
Kardiologie 17
(3): 173-185.
June 2023
Visual function resists early neurodegeneration in the visual system in primary progressive multiple sclerosis.
Rosenkranz, S.C., Gutmann, L., Has Silemek, A.C., Dorr, M., Häußler, V., Lüpke, M., Mönch, A., Reinhardt, S., Kuhle, J., Tilsley, P., Heesen, C., Friese, M.A., Brandt, A., Paul, F., Zimmermann, H. and Stellmann, J.P.
Journal of Neurology, Neurosurgery, and Psychiatry 94
(11): 924-933.
12 October 2023
HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
Rosiewicz, K.S., Muinjonov, B., Kunz, S., Radbruch, H., Chen, J., Jüttner, R., Kerkering, J., Ucar, J., Crowley, T., Wielockx, B., Paul, F., Alisch, M. and Siffrin, V.
Glia 71
(8): 2024-2044.
August 2023
TapA acts as specific chaperone in TasA filament formation by strand complementation.
Roske, Y., Lindemann, F., Diehl, A., Cremer, N., Higman, V.A., Schlegel, B., Leidert, M., Driller, K., Turgay, K., Schmieder, P., Heinemann, U. and Oschkinat, H.
Proceedings of the National Academy of Sciences of the United States of America 120
(17): e2217070120.
25 April 2023
Genomic ALK alterations in primary and relapsed neuroblastoma.
Rosswog, C., Fassunke, J., Ernst, A., Schömig-Markiefka, B., Merkelbach-Bruse, S., Bartenhagen, C., Cartolano, M., Ackermann, S., Theissen, J., Blattner-Johnson, M., Jones, B., Schramm, K., Altmüller, J., Nürnberg, P., Ortmann, M., Berthold, F., Peifer, M., Büttner, R., Westermann, F., Schulte, J.H., Simon, T., Hero, B. and Fischer, M.
British Journal of Cancer 128
(8): 1559-1571.
12 April 2023
Inhibitory effect of isopanduratin A on adipogenesis: a study of possible mechanisms.
Rungsa, P., San, H.T., Sritularak, B., Böttcher, C., Prompetchara, E., Chaotham, C. and Likhitwitayawuid, K.
Foods 12
(5): 1014.
27 February 2023
The potential of cross-linking mass spectrometry in the development of protein-protein interaction modulators.
Ruwolt, M., Piazza, I. and Liu, F.
Current Opinion in Structural Biology 82
: 102648.
October 2023
Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.
Rybak-Wolf, A., Wyler, E., Pentimalli, T.M., Legnini, I., Oliveras Martinez, A., Glažar, P., Loewa, A., Kim, S.J., Kaufer, B.B., Woehler, A., Landthaler, M. and Rajewsky, N.
Nature Microbiology 8
(7): 1252-1266.
July 2023
Advanced radio frequency applicators for thermal magnetic resonance theranostics of brain tumors.
Saha, N., Kuehne, A., Millward, J.M., Eigentler, T.W., Starke, L., Waiczies, S. and Niendorf, T.
Cancers 15
(8): 2303.
14 April 2023
High fidelity 3D magnetic stray field mapping of smartphones to address safety considerations with active implantable electronic medical devices.
Saha, N., Millward, J.M., Herrmann, C.J.J., Rahimi, F., Han, H., Lacour, P., Blaschke, F. and Niendorf, T.
Sensors 23
(3): 1209.
20 January 2023
Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer.
Saini, M., Schmidleitner, L., Moreno, H.D., Donato, E., Falcone, M., Bartsch, J.M., Vogel, V., Würth, R., Pfarr, N., Espinet, E., Lehmann, M., Königshoff, M., Reitberger, M., Haas, S., Graf, E., Schwarzmayr, T., Strom, T.M., Spaich, S., Sütterlin, M., Schneeweiss, A., Weichert, W., Schotta, G., Reichert, M., Aceto, N., Sprick, M.R., Trumpp, A., Scheel, C.H. and Klein, C.
Cell Reports 42
(6): 112533.
27 June 2023
Factors associated with depressive mood at the onset of multiple sclerosis - an analysis of 781 patients of the German NationMS cohort.
Salmen, A., Hoepner, R., Fleischer, V., Heldt, M., Gisevius, B., Motte, J., Ruprecht, K., Schneider, R., Fisse, A.L., Grüter, T., Lukas, C., Berthele, A., Giglhuber, K., Flaskamp, M., Mühlau, M., Kirschke, J., Bittner, S., Groppa, S., Lüssi, F., Bayas, A., Meuth, S., Heesen, C., Trebst, C., Wildemann, B., Then Bergh, F., Antony, G., Kümpfel, T., Paul, F., Nischwitz, S., Tumani, H., Zettl, U., Hemmer, B., Wiendl, H., Zipp, F. and Gold, R.
Therapeutic Advances in Neurological Disorders 16
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8 September 2023
Microfibrillar-associated protein 4 as a potential marker of acute relapse in inflammatory demyelinating diseases of the central nervous system: pathological and clinical aspects.
Samadzadeh, S., Olesen, M.N., Wirenfeldt, M., Möller, S., Misu, T., Soelberg, K., Frederiksen, J.L., Heegaard, S., Mariotto, S., Fujihara, K., Ruprecht, K., Andersen, T.L., Marignier, R., Lillevang, S.T., Flanagan, E.P., Pittock, S.J., Kim, H.J., Bennett, J.L., Paul, F., Sorensen, G.L., Weinshenker, B.G., Lassmann, H. and Asgari, N.
Multiple Sclerosis Journal 29
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14 December 2023
VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats.
Samuelsson, A.M., Bartolomaeus, T.U.P., Anandakumar, H., Thowsen, I., Nikpey, E., Han, J., Marko, L., Finne, K., Tenstad, O., Eckstein, J., Berndt, N., Kühne, T., Kedziora, S., Sultan, I., Skogstrand, T., Karlsen, T.V., Nurmi, H., Forslund, S.K., Bollano, E., Alitalo, K., Muller, D.N. and Wiig, H.
Cardiovascular Research 119
(7): 1553-1567.
4 July 2023
Transgenic angiotensin-converting enzyme 2 overexpression in the rat vasculature protects kidneys from ageing-induced injury.
Sanad, A.M., Qadri, F., Popova, E., Rodrigues, A.F., Heinbokel, T., Quach, S., Schulz, A., Bachmann, S., Kreutz, R., Alenina, N. and Bader, M.
Kidney International 104
(2): 293-304.
August 2023
Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.
Sandmann, C.L., Schulz, J.F., Ruiz-Orera, J., Kirchner, M., Ziehm, M., Adami, E., Marczenke, M., Christ, A., Liebe, N., Greiner, J., Schoenenberger, A., Mücke, M.B., Liang, N., Moritz, R.L., Sun, Z., Deutsch, E.W., Gotthardt, M., Mudge, J.M., Prensner, J.R., Willnow, T.E., Mertins, P., van Heesch, S. and Hubner, N.
Molecular Cell 83
(6): 994-1011.e18.
16 March 2023
Proglucagon signalling in the rat dorsomedial hypothalamus - physiology and high-fat diet-mediated alterations.
Sanetra, A M., Palus-Chramiec, K., Chrobok, L., Jeczmien-Lazur, J.S., Klich, J.D. and Lewandowski, M.H.
Molecular and Cellular Neuroscience 126
: 103873.
September 2023
Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis.
Schaupp, L., Addante, A., Völler, M., Fentker, K., Kuppe, A., Bardua, M., Duerr, J., Piehler, L., Röhmel, J., Thee, S., Kirchner, M., Ziehm, M., Lauster, D., Haag, R., Gradzielski, M., Stahl, M., Mertins, P., Boutin, S., Graeber, S.Y. and Mall, M.A.
European Respiratory Journal 62
(2): 2202153.
1 August 2023
Pre-operative radiotherapy is associated with superior local relapse-free survival in advanced synovial sarcoma.
Scheer, M., Hallmen, E., Vokuhl, C., Fuchs, J., Tunn, P.U., Münter, M., Timmermann, B., Bauer, S., Henssen, A.G., Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Eggert, A., Klingebiel, T. and Koscielniak, E.
Journal of Cancer Research and Clinical Oncology 149
(5): 1717-1731.
May 2023
Fighting post-COVID and ME/CFS - development of curative therapies.
Scheibenbogen, C., Bellmann-Strobl, J.T., Heindrich, C., Wittke, K., Stein, E., Franke, C., Prüss, H., Preßler, H., Machule, M.L., Audebert, H., Finke, C., Zimmermann, H.G., Sawitzki, B., Meisel, C., Toelle, M., Krueger, A., Aschenbrenner, A.C., Schultze, J.L., Beyer, M.D., Ralser, M., Mülleder, M., Sander, L.E., Konietschke, F., Paul, F., Stojanov, S., Bruckert, L., Hedderich, D.M., Knolle, F., Riemekasten, G., Vehreschild, M.J.G.T., Cornely, O.A., Behrends, U. and Burock, S.
Frontiers in Medicine 10
2023
Induction of kidney-related gene programs through co-option of SALL1 in mole ovotestes.
Schindler, M., Osterwalder, M., Harabula, I., Wittler, L., Tzika, A.C., Dechmann, D.K.N., Vingron, M., Visel, A., Haas, S. and Real, F.M.
Development 150
(17): dev201562.
1 September 2023
Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner, N., Cauchy, P., Franke, V., Giefing, M., Fornes, O., Vankadari, N., Assi, S.A., Costanza, M., Weniger, M.A., Akalin, A., Anagnostopoulos, I., Bukur, T., Casarotto, M.G., Damm, F., Daumke, O., Edginton-White, B., Gebhardt, J.C.M., Grau, M., Grunwald, S., Hansmann, M.L., Hartmann, S., Huber, L., Kärgel, E., Lusatis, S., Noerenberg, D., Obier, N., Pannicke, U., Fischer, A., Reisser, A., Rosenwald, A., Schwarz, K., Sundararaj, S., Weilemann, A., Winkler, W., Xu, W., Lenz, G., Rajewsky, K., Wasserman, W.W., Cockerill, P.N., Scheidereit, C., Siebert, R., Küppers, R., Grosschedl, R., Janz, M., Bonifer, C. and Mathas, S.
Nature Communications 14
(1): 6947.
7 November 2023
COVID-19 and cellular senescence.
Schmitt, C.A., Tchkonia, T., Niedernhofer, L.J., Robbins, P.D., Kirkland, J.L. and Lee, S.
Nature Reviews Immunology 23
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April 2023
Clinical rating scales for ataxia.
Schmitz-Hübsch, T.
Contemporary Clinical Neuroscience
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30 May 2023
Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen.
Schmutz, M., Zucknick, M., Schlenk, R.F., Mertens, D., Benner, A., Weichenhan, D., Mücke, O., Döhner, K., Plass, C., Bullinger, L. and Claus, R.
Clinical Epigenetics 15
(1): 171.
26 October 2023
Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly.
Schnabel, F., Schuler, E., Al-Maawali, A., Chaurasia, A., Syrbe, S., Al-Kindi, A., Bhavani, G.S., Shukla, A., Altmüller, J., Nürnberg, P., Banka, S., Girisha, K.M., Li, Y., Wollnik, B. and Yigit, G.
Human Genetics 142
(4): 543-552.
April 2023
A colonic organoid model challenged with the large toxins of Clostridioides difficile TcdA and TcdB exhibit deregulated tight junction proteins.
Schneemann, M., Heils, L., Moos, V., Weiß, F., Krug, S.M., Weiner, J., Beule, D., Gerhard, R., Schulzke, J.D. and Bücker, R.
Toxins 15
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4 November 2023
Disintegration of the NuRD complex in primary human muscle stem cells in critical illness myopathy.
Schneider, J., Sundaravinayagam, D., Blume, A., Marg, A., Grunwald, S., Metzler, E., Escobar, H., Müthel, S., Wang, H., Wollersheim, T., Weber-Carstens, S., Akalin, A., Di Virgilio, M., Tursun, B. and Spuler, S.
International Journal of Molecular Sciences 24
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1 February 2023
The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis.
Schoeler, M., Ellero-Simatos, S., Birkner, T., Mayneris-Perxachs, J., Olsson, L., Brolin, H., Löber, U., Kraft, J.D., Polizzi, A., Martí-Navas, M., Puig, J., Moschetta, A., Montagner, A., Gourdy, P., Heymes, C., Guillou, H., Tremaroli, V., Fernández-Real, J.M., Forslund, S.K., Burcelin, R. and Caesar, R.
Nature Communications 14
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1 September 2023
Target selection for T-cell therapy in epithelial ovarian cancer: systematic prioritization of self-antigens.
Schossig, P., Coskun, E., Arsenic, R., Horst, D., Sehouli, J., Bergmann, E., Andresen, N., Sigler, C., Busse, A., Keller, U. and Ochsenreither, S.
International Journal of Molecular Sciences 24
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24 January 2023
The genetic spectrum of congenital ocular motor apraxia type Cogan: an observational study, continued.
Schröder, S., Yigit, G., Li, Y., Altmüller, J., Büttel, H.M., Fiedler, B., Kretzschmar, C., Nürnberg, P., Seeger, J., Serpieri, V., Valente, E.M., Wollnik, B., Boltshauser, E. and Brockmann, K.
Orphanet Journal of Rare Diseases 18
(1): 101.
2 May 2023
Treatment of adult ALL patients with third-generation CD19-directed CAR T cells: results of a pivotal trial.
Schubert, M.L., Schmitt, A., Hückelhoven-Krauss, A., Neuber, B., Kunz, A., Waldhoff, P., Vonficht, D., Yousefian, S., Jopp-Saile, L., Wang, L., Korell, F., Keib, A., Michels, B., Haas, D., Sauer, T., Derigs, P., Kulozik, A., Kunz, J., Pavel, P., Laier, S., Wuchter, P., Schmier, J., Bug, G., Lang, F., Gökbuget, N., Casper, J., Görner, M., Finke, J., Neubauer, A., Ringhoffer, M., Wolleschak, D., Brüggemann, M., Haas, S., Ho, A.D., Müller-Tidow, C., Dreger, P. and Schmitt, M.
Journal of Hematology & Oncology 16
(1): 79.
22 July 2023
Similar neural pathways link psychological stress and brain-age in health and multiple sclerosis.
Schulz, M.A., Hetzer, S., Eitel, F., Asseyer, S., Meyer-Arndt, L., Schmitz-Hübsch, T., Bellmann-Strobl, J., Cole, J.H., Gold, S.M., Paul, F., Ritter, K. and Weygandt, M.
iScience 26
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15 September 2023
Automated image quality assessment for selecting among multiple magnetic resonance image acquisitions in the German National Cohort study.
Schuppert, C., Rospleszcz, S., Hirsch, J.G., Hoinkiss, D.C., Köhn, A., von Krüchten, R., Russe, M.F., Keil, T., Krist, L., Schmidt, B., Michels, K.B., Schipf, S., Brenner, H., Kröncke, T.J., Pischon, T., Niendorf, T., Schulz-Menger, J., Forsting, M., Völzke, H., Hosten, N., Bülow, R., Zaitsev, M., Kauczor, H.U., Bamberg, F., Günther, M. and Schlett, C.L.
Scientific Reports 13
(1): 22745.
20 December 2023
The cytomegalovirus M35 protein directly binds to the interferon-β enhancer and modulates transcription of (Ifnb1) and other IRF3-driven genes.
Schwanke, H., Gonçalves Magalhães, V., Schmelz, S., Wyler, E., Hennig, T., Günther, T., Grundhoff, A., Dölken, L., Landthaler, M., van Ham, M., Jänsch, L., Büssow, K., van den Heuvel, J., Blankenfeldt, W., Friedel, C.C., Erhard, F. and Brinkmann, M.M.
Journal of Virology 97
(6): e0040023.
29 June 2023
Chronic disease outcome metadata from German observational studies – public availability and FAIR principles.
Schwedhelm, C., Nimptsch, K., Ahrens, W., Hasselhorn, H.M., Jöckel, K.H., Katzke, V., Kluttig, A., Linkohr, B., Mikolajczyk, R., Nöthlings, U., Perrar, I., Peters, A., Schmidt, C.O., Schmidt, B., Schulze, M.B., Stang, A., Zeeb, H. and Pischon, T.
Scientific Data 10
: 868.
5 December 2023
Myocarditis and sports in the young: data from a nationwide registry on myocarditis - "MYKKE-Sport".
Schöffl, I., Holler, S., Dittrich, S., Pickardt, T., Opgen-Rhein, B., Boehne, M., Wannenmacher, B., Reineke, K., Wiegand, G., Hecht, T., Kaestner, M., Messroghli, D., Schubert, S., Seidel, F. and Weigelt, A.
Frontiers in Sports and Active Living 5
: 1197640.
26 June 2023
Cantharidin and its analogue norcantharidin inhibit metastasis-inducing genes S100A4 and MACC1.
Schöpe, P.C., Zinnow, V., Ishfaq, M.A., Smith, J., Herrmann, P., Shoemaker, R.H., Walther, W. and Stein, U.
International Journal of Molecular Sciences 24
(2): 1179.
7 January 2023
The interactive complex between cytomegalovirus kinase vCDK/pUL97 and host factors CDK7-cyclin H determines individual patterns of transcription in infected cells.
Schütz, M., Cordsmeier, A., Wangen, C., Horn, A.H.C., Wyler, E., Ensser, A., Sticht, H. and Marschall, M.
International Journal of Molecular Sciences 24
(24): 17421.
13 December 2023
Broadening the phenotypic and molecular spectrum of FINCA syndrome: Biallelic NHLRC2 variants in 15 novel individuals.
Sczakiel, H.L., Zhao, M., Wollert-Wulf, B., Danyel, M., Ehmke, N., Stoltenburg, C., Damseh, N., Al-Ashhab, M., Balci, T.B., Osmond, M., Andrade, A., Schallner, J., Porrmann, J., McDonald, K., Liao, M., Oppermann, H., Platzer, K., Dierksen, N., Mojarrad, M., Eslahi, A., Bakaeean, B., Calame, D.G., Lupski, J.R., Firoozfar, Z., Seyedhassani, S.M., Mohammadi, S.A., Anwaar, N., Rahman, F., Seelow, D., Janz, M., Horn, D., Maroofian, R. and Boschann, F.
European Journal of Human Genetics 31
(8): 905-317.
August 2023
Novel multi-objective affinity approach allows to identify pH-specific μ-opioid receptor agonists.
Secker, C., Fackeldey, K., Weber, M., Ray, S., Gorgulla, C. and Schütte, C.
Journal of Cheminformatics 15
(1): 85.
19 September 2023
The polyphenol EGCG directly targets intracellular amyloid-β aggregates and promotes their lysosomal degradation.
Secker, C., Motzny, A.Y., Kostova, S., Buntru, A., Helmecke, L., Reus, L., Steinfort, R., Brusendorf, L., Boddrich, A., Neuendorf, N., Diez, L., Schmieder, P., Schulz, A., Czekelius, C. and Wanker, E.E.
Journal of Neurochemistry 166
(2): 294-317.
18 July 2023
A circular RNA expressed from the FAT3 locus regulates neural development.
Seeler, S., Andersen, M.S., Sztanka-Toth, T., Rybiczka-Tešulov, M., van den Munkhof, M.H., Chang, C.C., Maimaitili, M., Venø, M.T., Hansen, T.B., Pasterkamp, R.J., Rybak-Wolf, A., Denham, M., Rajewsky, N., Kristensen, L.S. and Kjems, J.
Molecular Neurobiology 60
(6): 3239–3260.
June 2023
Potentiating tweezer affinity to a protein interface with sequence-defined macromolecules on nanoparticles.
Seiler, T., Lennartz, A., Klein, K., Hommel, K., Figueroa Bietti, A., Hadrovic, I., Kollenda, S., Sager, J., Beuck, C., Chlosta, E., Bayer, P., Juul-Madsen, K., Vorup-Jensen, T., Schrader, T., Epple, M., Knauer, S.K. and Hartmann, L.
Biomacromolecules 24
(8): 3666-3679.
14 August 2023
Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury.
Sieckmann, T., Schley, G., Ögel, N., Kelterborn, S., Boivin, F.J., Fähling, M., Ashraf, M.I., Reichel, M., Vigolo, E., Hartner, A., Lichtenberger, F.B., Breiderhoff, T., Knauf, F., Rosenberger, C., Aigner, F., Schmidt-Ott, K., Scholz, H. and Kirschner, K.M.
Kidney International 104
(1): 90-107.
July 2023
GIPC1 regulates MACC1-driven metastasis.
Siegel, F., Schmidt, H., Juneja, M., Smith, J., Herrmann, P., Kobelt, D., Sharma, K., Fichtner, I., Walther, W., Dittmar, G., Volkmer, R., Rathjen, F.G., Schlag, P.M. and Stein, U.
Frontiers in Oncology 13
: 1280977.
8 December 2023
Worldwide variation in cardiovascular magnetic resonance practice models.
Sierra-Galan, L.M., Estrada-Lopez, E.E.S., Ferrari, V.A., Raman, S.V., Ferreira, V.M., Raj, V., Joseph, E., Schulz-Menger, J., Chan, C.W.S., Chen, S.S.M., Cheng, Y., De Lara Fernandez, J., Terashima, M. and Albert, T.S.E.
Journal of Cardiovascular Magnetic Resonance 25
(1): 38.
3 July 2023
Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.
Silva, R.V., Biskup, K., Zabala-Jouvin, J.K., Batzdorf, C.S., Stellmach, C., Morr, A.S., Sack, I., Ludwig, A., Blanchard, V. and Infante-Duarte, C.
International Journal of Biological Macromolecules 230
: 123214.
March 2023
In vitro production of naked mole-rats' blastocysts from non-breeding females using in vitro maturation and intracytoplasmic sperm injection.
Simone, R., Čižmár, D., Holtze, S., Michel, G., Sporbert, A., Okolo, C. and Hildebrandt, T.B.
Scientific Reports 13
(1): 22355.
15 December 2023
Tryptophan hydroxylase-2-mediated serotonin biosynthesis suppresses cell reprogramming into pluripotent state.
Sinenko, S.A., Kuzmin, A.A., Skvortsova, E.V., Ponomartsev, S.V., Efimova, E.V., Bader, M., Alenina, N. and Tomilin, A.N.
International Journal of Molecular Sciences 24
(5): 4862.
2 March 2023
A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass.
Singh, M., Kondrashkina, A., Widmann, T.J., Cortes, J.L., Bansal, V., Wang, J., Römer, C., Garcia-Canadas, M., Garcia-Perez, J.L., Hurst, L.D. and Izsvak, Z.
PLoS Biology 21
(6): e3002162.
20 June 2023
Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.
Smith, E.J., Sathasivam, K., Landles, C., Osborne, G.F., Mason, M.A., Gomez-Paredes, C., Taxy, B.A., Milton, R.E., Ast, A., Schindler, F., Zhang, C., Duan, W., Wanker, E.E. and Bates, G.P.
Brain Communications 5
(1): fcad010.
20 January 2023
Impaired T cell IRE1α-XBP1 signaling directs inflammation in experimental Heart Failure with Preserved Ejection Fraction.
Smolgovsky, S., Bayer, A.L., Kaur, K., Sanders, E., Aronovitz, M., Filipp, M.E., Thorp, E.B., Schiattarella, G.G., Hill, J.A., Blanton, R.M., Cubillos-Ruiz, J.R. and Alcaide, P.
Journal of Clinical Investigation 133
(24): e171874.
15 December 2023
Urinary T cells identify renal antineutrophil cytoplasmic antibody-associated vasculitis and predict prognosis: a proof of concept study.
Sonnemann, J., Klocke, J., Bieringer, M., Rousselle, A., Eckardt, K.U., Elitok, S., Popovic, S., Bachmann, S., Kettritz, R., Salama, A.D., Enghard, P. and Schreiber, A.
Kidney International Reports 8
(4): 871-883.
April 2023
Structure-based design of xanthine-imidazopyridines and -imidazothiazoles as highly potent and in vivo efficacious tryptophan hydroxylase inhibitors.
Specker, E., Wesolowski, R., Schütz, A., Matthes, S., Mallow, K., Wasinska-Kalwa, M., Winkler, L., Oder, A., Alenina, N., Pleimes, D., von Kries, J.P., Heinemann, U., Bader, M. and Nazaré, M.
Journal of Medicinal Chemistry 66
(21): 14866-14896.
9 November 2023
Depressive symptoms and anti-N-methyl-D-aspartate-receptor GluN1 antibody seropositivity in the PROSpective cohort with incident stroke.
Sperber, P.S., Gebert, P., Broersen, L.H.A., Kufner, A., Huo, S., Piper, S.K., Teegen, B., Heuschmann, P.U., Prüss, H., Endres, M., Liman, T.G. and Siegerink, B.
Brain Behavior & Immunity - Health 34
: 100705.
December 2023
BLN protein induces cardiac hypertrophy and failure.
Sperling, S.R.
Nature Cardiovascular Research 2
(11): 964-965.
November 2023
Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation.
Sporre, E., Karlsen, J., Schriever, K., Asplund-Samuelsson, J., Janasch, M., Strandberg, L., Karlsson, A., Kotol, D., Zeckey, L., Piazza, I., Syrén, P.O., Edfors, F. and Hudson, E.P.
Communications Biology 6
(1): 947.
18 September 2023
Thrifty energy phenotype predicts weight regain in postmenopausal women with overweight or obesity and is related to FGFR1 signaling.
Spranger, L., Weiner, J., Bredow, J., Zeitz, U., Grittner, U., Boschmann, M., Dickmann, S., Stobäus, N., Schwartzenberg, R.J., Brachs, M., Spranger, J. and Mai, K.
Clinical Nutrition 42
(4): 559-567.
April 2023
Consensus molecular subtypes as biomarkers of fluorouracil and folinic acid maintenance therapy with or without panitumumab in (RAS) wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212).
Stahler, A., Hoppe, B., Na, I.K., Keilholz, L., Müller, L., Karthaus, M., Fruehauf, S., Graeven, U., Fischer von Weikersthal, L., Goekkurt, E., Kasper, S., Kind, A.J., Kurreck, A., Alig, A.H.S., Held, S., Reinacher-Schick, A., Heinemann, V., Horst, D., Jarosch, A., Stintzing, S., Trarbach, T. and Modest, D.P.
Journal of Clinical Oncology 41
(16): 2975-2987.
1 June 2023
First in vivo fluorine-19 magnetic resonance imaging of the multiple sclerosis drug siponimod.
Starke, L., Millward, J.M., Prinz, C., Sherazi, F., Waiczies, H., Lippert, C., Nazaré, M., Paul, F., Niendorf, T. and Waiczies, S.
Theranostics 13
(4): 1217-1234.
5 February 2023
CYCLeR - a novel tool for the full isoform assembly and quantification of circRNAs.
Stefanov, S.R. and Meyer, I.M.
Nucleic Acids Research 51
(2): e10.
25 January 2023
Doxorubicin changes the spatial organization of the genome around active promoters.
Stefanova, M.E., Ing-Simmons, E., Stefanov, S., Flyamer, I., Dorado Garcia, H., Schöpflin, R., Henssen, A.G., Vaquerizas, J.M. and Mundlos, S.
Cells 12
(15): 2001.
4 August 2023
Leveraging ligand affinity and properties: discovery of novel benzamide-type cereblon binders for the design of PROTACs.
Steinebach, C., Bricelj, A., Murgai, A., Sosič, I., Bischof, L., Ng, Y.L.D., Heim, C., Maiwald, S., Proj, M., Voget, R., Feller, F., Košmrlj, J., Sapozhnikova, V., Schmidt, A., Zuleeg, M.R., Lemnitzer, P., Mertins, P., Hansen, F.K., Gütschow, M., Krönke, J. and Hartmann, M.D.
Journal of Medicinal Chemistry 66
(21): 14513-14543.
9 November 2023
Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome - State of the art: Report of the 2nd international meeting at the Charité fatigue center.
Steiner, S., Fehrer, A., Hoheisel, F., Schoening, S., Aschenbrenner, A., Babel, N., Bellmann-Strobl, J., Finke, C., Fluge, Ø., Froehlich, L., Goebel, A., Grande, B., Haas, J.P., Hohberger, B., Jason, L.A., Komaroff, A.L., Lacerda, E., Liebl, M., Maier, A., Mella, O., Nacul, L., Paul, F., Prusty, B.K., Puta, C., Riemekasten, G., Ries, W., Rowe, P.C., Sawitzki, B., Shoenfeld, Y., Schultze, J.L., Seifert, M., Sepúlveda, N., Sotzny, F., Stein, E., Stingl, M., Ufer, F., Veauthier, C., Westermeier, F., Wirth, K., Wolfarth, B., Zalewski, P., Behrends, U. and Scheibenbogen, C.
Autoimmunity Reviews 22
(11): 103452.
November 2023
A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity.
Stern, D., Meyer, T.C., Treindl, F., Mages, H.W., Krüger, M., Skiba, M., Krüger, J.P., Zobel, C.M., Schreiner, M., Grossegesse, M., Rinner, T., Peine, C., Stoliaroff-Pépin, A., Harder, T., Hofmann, N., Michel, J., Nitsche, A., Stahlberg, S., Kneuer, A., Sandoni, A., Kubisch, U., Schlaud, M., Mankertz, A., Schwarz, T., Corman, V.M., Müller, M.A., Drosten, C., de la Rosa, K., Schaade, L., Dorner, M.B. and Dorner, B.G.
Scientific Reports 13
(1): 21846.
9 December 2023
Epigenetic regulation of plastin 3 expression by the macrosatellite DXZ4 and the transcriptional regulator CHD4.
Strathmann, E.A., Hölker, I., Tschernoster, N., Hosseinibarkooie, S., Come, J., Martinat, C., Altmüller, J. and Wirth, B.
American Journal of Human Genetics 110
(3): 442-459.
2 March 2023
Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia.
Straube, J., Eifert, T., Vu, T., Janardhanan, Y., Haldar, R., von Eyss, B., Cooper, L., Bruedigam, C., Ling, V.Y., Cooper, E., Patch, A.M., Bullinger, L., Schnoeder, T.M., Bywater, M., Heidel, F.H. and Lane, S.W.
Leukemia 37
(4): 741-750.
April 2023
SMITH: spatially constrained stochastic model for simulation of intra-tumour heterogeneity.
Streck, A., Kaufmann, T.L. and Schwarz, R.F.
Bioinformatics 39
(3): btad102.
March 2023
The interplay of family history of depression and early trauma: associations with lifetime and current depression in the German national cohort (NAKO).
Streit, F., Völker, M.P., Klinger-König, J., Zillich, L., Frank, J., Reinhard, I., Foo, J.C., Witt, S.H., Sirignano, L., Becher, H., Obi, N., Riedel, O., Do, S., Castell, S., Hassenstein, M.J., Karch, A., Stang, A., Schmidt, B., Schikowski, T., Stahl-Pehe, A., Brenner, H., Perna, L., Greiser, K.H., Kaaks, R., Michels, K.B., Franzke, C.W., Peters, A., Fischer, B., Konzok, J., Mikolajczyk, R., Führer, A., Keil, T., Fricke, J., Willich, S.N., Pischon, T., Völzke, H., Meinke-Franze, C., Loeffler, M., Wirkner, K., Berger, K., Grabe, H.J. and Rietschel, M.
Frontiers in Epidemiology 3
: 1099235.
23 May 2023
Sarcoma patients admitted to the intensive care unit (ICU): predictive relevance of common sepsis and performance parameters.
Striefler, J.K., Binder, P.T., Brandes, F., Rau, D., Wittenberg, S., Kaul, D., Roohani, S., Jarosch, A., Schäfer, F.M., Öllinger, R., Märdian, S., Bullinger, L., Eckardt, K.U., Kruse, J. and Flörcken, A.
Cancer Management and Research 15
: 321-334.
27 March 2023
Integrated proteomics unveils nuclear PDE3A2 as a regulator of cardiac myocyte hypertrophy.
Subramaniam, G., Schleicher, K., Kovanich, D., Zerio, A., Folkmanaite, M., Chao, Y.C., Surdo, N.C., Koschinski, A., Hu, J., Scholten, A., Heck, A.J.R, Ercu, M., Sholokh, A., Chan Park, K., Klussmann, E., Meraviglia, V., Bellin, M., Zanivan, S., Hester, S., Mohammed, S. and Zaccolo, M.
Circulation Research 132
(7): 828-848.
31 March 2023
Long-read sequencing reveals extensive DNA methylations in human gut phagenome contributed by prevalently phage-encoded methyltransferases.
Sun, C., Chen, J., Jin, M., Zhao, X., Li, Y., Dong, Y., Gao, N., Liu, Z., Bork, P., Zhao, X.M. and Chen, W.H.
Advanced Science 10
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5 September 2023
Stress-induced nuclear speckle reorganization is linked to activation of immediate early gene splicing.
Sung, H.M., Schott, J., Boss, P., Lehmann, J.A., Hardt, M.R., Lindner, D., Messens, J., Bogeski, I., Ohler, U. and Stoecklin, G.
Journal of Cell Biology 222
(12): e202111151.
4 December 2023
Angiotensin-(1-7) mediated calcium signalling by MAS.
Sureshkumar, P., Souza dos Santos, R.A., Alenina, N., Mergler, S. and Bader, M.
Peptides 165
: 171010.
July 2023
Risk of pre-term birth as a function of sleep quality and obesity: prospective analysis in a large Prematurity Research Cohort.
Sutcliffe, S., Zhao, P., Pilz, L.K., Oakes, M., Frolova, A.I., Herzog, E.D. and England, S.K.
Sleep Advances 4
(1): zpad043.
13 November 2023
Digital motor biomarkers of cerebellar ataxia using an RGB-Depth camera-based motion analysis system.
Suzuki, M., Hirano, S., Otte, K., Schmitz-Hübsch, T., Izumi, M., Tamura, M., Kuroiwa, R., Sugiyama, A., Mori, M., Röhling, H.M., Brandt, A.U., Murata, A., Paul, F. and Kuwabara, S:
Cerebellum 23
(3): 1031-1041.
January 2023
The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest.
Szklarczyk, D., Kirsch, R., Koutrouli, M., Nastou, K., Mehryary, F., Hachilif, R., Gable, A.L., Fang, T., Doncheva, N.T., Pyysalo, S., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 51
(D1): D638-D646.
6 January 2023
Insm1 regulates mTEC development and immune tolerance.
Tao, W., Ye, Z., Wei, Y., Wang, J., Yang, W., Yu, G., Xiong, J. and Jia, S.
Cellular and Molecular Immunology 20
(12): 1472-1486.
December 2023
Community survey results show that standardisation of preclinical imaging techniques remains a challenge.
Tavares, A.A.S., Mezzanotte, L., McDougald, W., Bernsen, M.R., Vanhove, C., Aswendt, M., Ielacqua, G.D., Gremse, F., Moran, C.M., Warnock, G., Kuntner, C. and Huisman, M.C.
Molecular imaging and biology 25
(3): 560-568.
June 2023
A fucoidan plant drink reduces Helicobacter pylori load in the stomach: a real-world study.
Teng, Q.L., Sui, S.J., Zhu, Z., Gao, Q., Ge, H., Wang, K.Q., Lino-Silva, L.S., Sigal, M., White, J.R., Peng, Q.H. and Wei, Y.Z.
Translational Gastroenterology and Hepatology 8
: 34-34.
30 October 2023
The gut microbiota in multiple sclerosis varies with disease activity.
Thirion, F., Sellebjerg, F., Fan, Y., Lyu, L., Hansen, T.H., Pons, N., Levenez, F., Quinquis, B., Stankevic, E., Søndergaard, H.B., Dantoft, T.M., Poulsen, C.S., Forslund, S.K., Vestergaard, H., Hansen, T., Brix, S., Oturai, A., Sørensen, P.S., Ehrlich, S.D. and Pedersen, O.
Genome Medicine 15
(1): 1.
5 January 2023
Alteration of gut microbiome in patients with schizophrenia indicates links between bacterial tyrosine biosynthesis and cognitive dysfunction.
Thirion, F., Speyer, H., Hansen, T.H., Nielsen, T., Fan, Y., Le Chatelier, E., Fromentin, S., Berland, M., Oñate, F.P., Pons, N., Galleron, N., Levenez, F., Markó, L., Birkner, T., Jørgensen, T., Forslund, S.K., Vestergaard, H., Hansen, T., Nordentoft, M., Mors, O., Benros, M.E., Pedersen, O. and Ehrlich, S.D.
Biological Psychiatry Global Open Science 3
(2): 283-291.
April 2023
Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
Torcal Garcia, G., Kowenz-Leutz, E., Tian, T.V, Klonizakis, A., Lerner, J., De Andres-Aguayo, L., Sapozhnikova, V., Berenguer, C., Carmona, M.P., Casadesus, M.V., Bulteau, R., Francesconi, M., Peiro, S., Mertins, P., Zaret, K., Leutz, A. and Graf, T.
eLife 12
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27 June 2023
Application of a spacer-nick gene-targeting approach to repair disease-causing mutations with increased safety.
Tran, N.T., Lebedin, M., Danner, E., Kühn, R., Rajewsky, K. and Chu, V.T.
Bio-protocol 13
(8): e4661.
20 April 2023
The fate of oxidative strand breaks in mitochondrial DNA.
Trombly, G., Said, A.M., Kudin, A.P., Peeva, V., Altmüller, J., Becker, K., Köhrer, K., Zsurka, G. and Kunz, W.S.
Antioxidants 12
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12 May 2023
Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions.
Tschernoster, N., Erger, F., Kohl, S., Reusch, B., Wenzel, A., Walsh, S., Thiele, H., Becker, C., Franitza, M., Bartram, M.P., Kömhoff, M., Schumacher, L., Kukat, C., Borodina, T., Quedenau, C., Nürnberg, P., Rinschen, M.M., Driller, J.H., Pedersen, B.P., Schlingmann, K.P., Hüttel, B., Bockenhauer, D., Beck, B. and Altmüller, J.
Genome Medicine 15
(1): 62.
23 August 2023
CORUM: the comprehensive resource of mammalian protein complexes-2022.
Tsitsiridis, G., Steinkamp, R., Giurgiu, M., Brauner, B., Fobo, G., Frishman, G., Montrone, C. and Ruepp, A.
Nucleic Acids Research 51
(D1): D539-D545.
6 January 2023
e-RNA: a collection of web-servers for the prediction and visualisation of RNA secondary structure and their functional features.
Tsybulskyi, V., Semenchenko, E. and Meyer, I.M.
Nucleic Acids Research 51
(W1): W160-W167.
5 July 2023
Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.
Urizar, A.I., Prause, M., Ingerslev, L.R., Wortham, M., Sui, Y., Sander, M., Williams, K., Barrès, R., Larsen, M.R., Christensen, G.L. and Billestrup, N.
Cell Death & Disease 14
(7): 399.
5 July 2023
Efficient generation of a self-organizing neuromuscular junction model from human pluripotent stem cells.
Urzi, A., Lahmann, I., Nguyen, L.V.N., Rost, B.R., García-Pérez, A., Lelievre, N., Merritt-Garza, M.E., Phan, H.C, Bassell, G.J., Rossoll, W., Diecke, S., Kunz, S., Schmitz, D. and Gouti, M.
Nature Communications 14
(1): 8043.
19 December 2023
Catenin signaling controls phrenic motor neuron development and function during a narrow temporal window.
Vagnozzi, A.N., Moore, M.T., López de Boer, R., Agarwal, A., Zampieri, N., Landmesser, L.T. and Philippidou, P.
Frontiers in Neural Circuits 17
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21 February 2023
A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.
Vallecillo-García, P., Orgeur, M., Comai, G., Poehle-Kronnawitter, S., Fischer, C., Gloger, M., Dumas, C.E., Giesecke-Thiel, C., Sauer, S., Tajbakhsh, S., Höpken, U.E. and Stricker, S.
Immunity 56
(6): 1204-1219.
13 June 2023
Clonally expanded PD-1-expressing T cells are enriched in synovial fluid of juvenile idiopathic arthritis patients.
Vanni, A., Mazzoni, A., Semeraro, R., Capone, M., Maschmeyer, P., Lamacchia, G., Salvati, L., Carnasciali, A., Farahvachi, P., Giani, T., Simonini, G., Filocamo, G., Romano, M., Liotta, F., Mashreghi, M.F., Cosmi, L., Cimaz, R., Magi, A., Maggi, L. and Annunziato, F.
European Journal of Immunology 53
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July 2023
Harnessing CD3 diversity to optimize CAR T cells.
Velasco Cárdenas, R.M.H., Brandl, S.M., Meléndez, A.V., Schlaak, A.E., Buschky, A., Peters, T., Beier, F., Serrels, B., Taromi, S., Raute, K., Hauri, S., Gstaiger, M., Lassmann, S., Huppa, J.B., Boerries, M., Andrieux, G., Bengsch, B., Schamel, W.W. and Minguet, S.
Nature Immunology 24
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December 2023
Daratumumab as a novel treatment option in refractory ITP.
Vernava, I. and Schmitt, C.A.
Blood Cells Molecules and Diseases 99
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March 2023
The cellular coding of temperature in the mammalian cortex.
Vestergaard, M., Carta, M., Güney, G. and Poulet, J.F.A.
Nature 614
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23 February 2023
G-protein-coupled receptor MAS DeLETION produces a preeclampsia-like phenotype in FVB/N mice.
Vieira Pimentel, R.L., Braga, J.F., Velloso, E.P.P., Lautner, R.Q., Oliveira, M.L., Todiras, M., Alenina, N., Bader, M., de Sousa, F.G., Beier, S.L. and Souza Dos Santos, R.A.
Clinical Science 137
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August 2023
Introduction of a cascaded segmentation pipeline for parametric T1 mapping in cardiovascular magnetic resonance to improve segmentation performance.
Viezzer, D., Hadler, T., Ammann, C., Blaszczyk, E., Fenski, M., Grandy, T.H., Wetzl, J., Lange, S. and Schulz-Menger, J.
Scientific Reports 13
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6 February 2023
Associations of accelerometer-based sedentary bouts with adiposity markers among German adults - results from a cross-sectional study.
Voigt, L., Ullrich, A., Groß, S., Guertler, D., Jaeschke, L., Dörr, M., van den Berg, N., John, U. and Ulbricht, S.
BMC Public Health 23
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10 March 2023
Increased mutation and gene conversion within human segmental duplications.
Vollger, M.R., Dishuck, P.C., Harvey, W.T., DeWitt, W.S., Guitart, X., Goldberg, M.E., Rozanski, A.N., Lucas, J., Asri, M., Munson, K.M., Lewis, A.P., Hoekzema, K., Logsdon, G.A., Porubsky, D., Paten, B., Harris, K., Hsieh, P.H. and Eichler, E.E.
Nature 617
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11 May 2023
Associations of migration, socioeconomic position and social relations with depressive symptoms – analyses of the German National Cohort baseline data.
Vonneilich, N., Becher, H., Bohn, B., Brandes, B., Castell, S., Deckert, A., Dragano, N., Franzke, C.W., Führer, A., Gastell, S., Greiser, H., Keil, T., Klett-Tammen, C., Koch-Gallenkamp, L., Krist, L., Leitzmann, M., Meinke-Franze, C., Mikolajczyk, R., Moreno Velasquez, I., Obi, N., Peters, A., Pischon, T., Reuter, M., Schikowski, T., Schmidt, B., Schulze, M., Sergeev, D., Stang, A., Völzke, H., Wiessner, C., Zeeb, H., Lüdecke, D. and von dem Knesebeck, O.
International Journal of Public Health 68
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18 July 2023
Impact of first-line use of caplacizumab on treatment outcomes in immune thrombotic thrombocytopenic purpura.
Völker, L.A., Kaufeld, J., Balduin, G., Merkel, L., Kühne, L., Eichenauer, D.A., Osterholt, T., Hägele, H., Kann, M., Grundmann, F., Kolbrink, B., Schulte, K., Gäckler, A., Kribben, A., Boss, K., Potthoff, S.A., Rump, L.C., Schmidt, T., Mühlfeld, A.S., Schulmann, K., Hermann, M., Gaedeke, J., Sauerland, K., Bramstedt, J., Hinkel, U.P., Miesbach, W., Bauer, F., Westhoff, T.H., Bruck, H., Buxhofer-Ausch, V., Müller, T.J., Wendt, R., Harth, A., Schreiber, A., Seelow, E., Tölle, M., Gohlisch, C., Bieringer, M., Geuther, G., Jabs, W.J., Fischereder, M., von Bergwelt-Baildon, A., Schönermarck, U., Knoebl, P., Menne, J. and Brinkkoetter, P.T.
Journal of Thrombosis and Haemostasis 21
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March 2023
Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia.
Wallach, T., Raden, M., Hinkelmann, L., Brehm, M., Rabsch, D., Weidling, H., Krüger, C., Kettenmann, H., Backofen, R. and Lehnardt, S.
Frontiers in Immunology 13
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13 January 2023
Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.
Wang, G., Chiou, J., Zeng, C., Miller, M., Matta, I., Han, J.Y., Kadakia, N., Okino, M.L., Beebe, E., Mallick, M., Camunas-Soler, J., Dos Santos, T., Dai, X.Q., Ellis, C., Hang, Y., Kim, S.K., MacDonald, P.E., Kandeel, F.R., Preissl, S., Gaulton, K.J. and Sander, M.
Nature Genetics 55
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June 2023
Associations of myeloid cells with cellular and humoral responses following vaccinations in patients with neuroimmunological diseases.
Wang, M., Dehlinger, A., Fernández Zapata, C., Golan, M., Gallaccio, G., Sander, L.E., Schlickeiser, S., Kunkel, D., Schmitz-Hübsch, T., Sawitzki, B., Karni, A., Braun, J., Loyal, L., Thiel, A., Bellmann-Strobl, J., Paul, F., Meyer-Arndt, L. and Boettcher, C.
Nature Communications 14
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25 November 2023
Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery.
Wang, Z., Shaabani, S., Gao, X., Ng, Y.L.D., Sapozhnikova, V., Mertins, P., Krönke, J. and Dömling, A.
Nature Communications 14
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19 December 2023
Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.
Watkins, T.B.K., Colliver, E.C., Huska, M.R., Kaufmann, T.L., Lim, E.L., Duncan, C.B., Haase, K., Van Loo, P., Swanton, C., McGranahan, N. and Schwarz, R.F.
PLoS Computational Biology 19
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23 October 2023
Retinal ganglion cell loss is associated with future disability worsening in early relapsing remitting multiple sclerosis.
Wauschkuhn, J., Solorza Buenrostro, G., Aly, L., Asseyer, S., Wicklein, R., Hartberger, J.M., Ruprecht, K., Mühlau, M., Schmitz-Hübsch, T., Chien, C., Berthele, A., Brandt, A.U., Korn, T., Paul, F., Hemmer, B., Zimmermann, H.G. and Knier, B.
European Journal of Neurology 30
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April 2023
Protocol of the Berlin Long-term Observation of Vascular Events (BeLOVE): a prospective cohort study with deep phenotyping and long-term follow up of cardiovascular high-risk patients.
Weber, J.E., Ahmadi, M., Boldt, L.H., Eckardt, K.U., Edelmann, F., Gerhardt, H., Grittner, U., Haubold, K., Hübner, N., Kollmus-Heege, J., Landmesser, U., Leistner, D.M., Mai, K., Müller, D.N., Nolte, C.H., Pieske, B., Piper, S.K., Rattan, S., Rauch, G., Schmidt, S., Schmidt-Ott, K.M., Schönrath, K., Schulz-Menger, J., Schweizerhof, O., Siegerink, B., Spranger, J., Ramachandran, V.S., Witzenrath, M., Endres, M. and Pischon, T.
BMJ Open 13
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31 October 2023
PEDL+: Protein-centered relation extraction from PubMed at your fingertip.
Weber, L., Barth, F., Lorenz, L., Konrath, F., Huska, K., Wolf, J. and Leser, U.
Bioinformatics 39
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November 2023
Gene editing in mouse zygotes using the CRISPR/Cas9 system.
Wefers, B., Wurst, W. and Kühn, R.
Methods in Molecular Biology 2631
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2023
Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Weigert, R., Hetzel, S., Bailly, N., Haggerty, C., Ilik, I.A., Yung, P.Y.K., Navarro, C., Bolondi, A., Kumar, A.S., Anania, C., Brändl, B., Meierhofer, D., Lupianez, D.G., Müller, F.J., Aktas, T., Elsässer, S.J., Kretzmer, H., Smith, Z.D. and Meissner, A.
Nature Cell Biology 25
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April 2023
Attack adjudication in neuromyelitis optica spectrum disorder: Substantiation of criteria by magnetic resonance imaging and biomarkers in N-MOmentum.
Weinshenker, B.G., Wingerchuk, D.M., Green, A.J., Bennett, J.L., Kim, H.J., Pittock, S.J., Fujihara, K., Paul, F., Cutter, G., Marignier, R., Aktas, O., Hartung, H.P., She, D., Smith, M., Rees, W., Patterson, K., Cimbora, D., Katz, E. and Cree, B.A.
Multiple Sclerosis Journal 29
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July 2023
Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial.
Weller, J., Schäfer, N., Schaub, C., Tzaridis, T., Zeyen, T., Schneider, M., Potthoff, A.L., Giordano, F.A., Steinbach, J.P., Zeiner, P.S., Kowalski, T., Sabel, M., Hau, P., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Tabatabai, G., Ringel, F., Schmidt-Graf, F., Brehmer, S., Tonn, J.C., Bullinger, L., Vajkoczy, P., Glas, M., Vatter, H., Herrlinger, U. and Seidel, C.
Journal of Neuro-Oncology 161
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January 2023
Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of adeno-associated virus vectors.
Westhaus, A., Cabanes Creus, M., Dilworth, K.L., Zhu, E., Salas, D., Navarro, R.G., Amaya, A.K., Scott, A., Kwiatek, M., McCorkindale, A.L., Hayman, T.E., Frahm, A., Perocheau, D., Tran, B.M., Vincan, E., Wong, S.L., Waters, S.A., Riddiough, G.E., Perini, M.V., Wilson, L.O.W., Baruteau, J., Diecke, S., Gonzalez-Aseguinolaza, G., Santilli, G., Thrasher, A.J., Alexander, I.E. and Lisowski, L.
Human Gene Therapy 34
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April 2023
Competency-based cardiac imaging for patient-centred care. A statement of the European Society of Cardiology (ESC). With the contribution of the European Association of Cardiovascular Imaging (EACVI), and the support of the Association of Cardiovascular Nursing & Allied Professions (ACNAP), the Association for Acute CardioVascular Care (ACVC), the European Association of Preventive Cardiology (EAPC), the European Association of Percutaneous Cardiovascular Interventions (EAPCI), the European Heart Rhythm Association (EHRA), and the Heart Failure Association (HFA) of the ESC.
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European Heart Journal - Imaging Methods and Practice 1
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September 2023
Competency-based cardiac imaging for patient-centred care. A statement of the European Society of Cardiology (ESC).
Westwood, M., Almeida, A.G., Barbato, E., Delgado, V., Dellegrottaglie, S., Fox, K.F., Gargani, L., Huber, K., Maurovich-Horvat, P., Merino, J.L., Mindham, R., Muraru, D., Neubeck, L., Nijveldt, R., Papadakis, M., Pontone, G., Price, S., Rosano, G.M.C., Rossi, A., Sade, L.E., Schulz-Menger, J., Weidinger, F., Achenbach, S. and Petersen, S.E.
European Heart Journal 44
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1 December 2023
Competency-based cardiac imaging for patient-centred care. A statement of the European Society of Cardiology (ESC).
Westwood, M., Almeida, A.G., Barbato, E., Delgado, V., Dellegrottaglie, S., Fox, K.F., Gargani, L., Huber, K., Maurovich-Horvat, P., Merino, J.L., Mindham, R., Muraru, D., Neubeck, L., Nijveldt, R., Papadakis, M., Pontone, G., Price, S., Rosano, G.M.C., Rossi, A., Sade, L.E., Schulz-Menger, J., Weidinger, F., Achenbach, S. and Petersen, S.E.
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November 2023
The OSCAR-MP consensus criteria for quality assessment of retinal optical coherence tomography angiography.
Wicklein, R., Yam, C., Noll, C., Aly, L., Banze, N., Romahn, E.F., Wolf, E., Hemmer, B., Oertel, F.C., Zimmermann, H., Albrecht, P., Ringelstein, M., Baumann, C., Feucht, N., Penkava, J., Havla, J., Gernert, J.A., Mardin, C., Vasileiou, E.S., Van Der Walt, A., Al-Louzi, O., Cabello, S., Vidal-Jordana, A., Krämer, J., Wiendl, H., Preiningerova, J.L., Ciccarelli, O., Garcia-Martin, E., Kana, V., Calabresi, P.A., Paul, F., Saidha, S., Petzold, A., Toosy, A.T. and Knier, B.
Neurology Neuroimmunology & Neuroinflammation 10
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November 2023
Changes of aortic hemodynamics after aortic valve replacement - a four dimensional flow cardiovascular magnetic resonance follow up study.
Wiesemann, S., Trauzeddel, R.F., Musa, A., Hickstein, R., Mayr, T., von Knobelsdorff-Brenkenhoff, F., Bollache, E., Markl, M. and Schulz-Menger, J.
Frontiers in Cardiovascular Medicine 10
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14 February 2023
Effectiveness of oral prednisone tapering following intravenous methylprednisolone for acute optic neuritis in multiple sclerosis.
Wilf-Yarkoni, A., Feldmann, K., Rubarth, K., Dorsch, E.M., Rust, R., Urman, I., Hellmann, M.A., Friedman, Y., Lotan, I., Bialer, O., Buenrostro, G.S., Zimmermann, H.G., Leutloff, C., Schmitz-Hübsch, T., Paul, F., Asseyer, S. and Stiebel-Kalish, H.
PLoS ONE 18
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7 December 2023
Mouse models of human multiple myeloma subgroups.
Winkler, W., Farré Díaz, C., Blanc, E., Napieczynska, H., Langner, P., Werner, M., Walter, B., Wollert-Wulf, B., Yasuda, T., Heuser, A., Beule, D., Mathas, S., Anagnostopoulos, I., Rosenwald, A., Rajewsky, K. and Janz, M.
Proceedings of the National Academy of Sciences of the United States of America 120
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7 March 2023
Heat in Germany: Health risks and preventive measures.
Winklmayr, C., Matthies-Wiesler, F., Muthers, S., Buchien, S., Kuch, B., An der Heiden, M. and Mücke, H.G.
Journal of Health Monitoring 8
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6 September 2023
Association of helicobacter pylori positivity with risk of disease and mortality.
Wizenty, J., Koop, P.H., Clusmann, J., Tacke, F., Trautwein, C., Schneider, K.M., Sigal, M. and Schneider, C.V.
Clinical and Translational Gastroenterology 14
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September 2023
Nutrient regulation of the islet epigenome controls adaptive insulin secretion.
Wortham, M., Liu, F., Harrington, A.R., Fleischman, J.Y., Wallace, M., Mulas, F., Mallick, M., Vinckier, N.K., Cross, B.R., Chiou, J., Patel, N.A., Sui, Y., McGrail, C., Jun, Y., Wang, G., Jhala, U.S., Schüle, R., Shirihai, O.S., Huising, M.O., Gaulton, K.J., Metallo, C.M. and Sander, M.
Journal of Clinical Investigation 133
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17 April 2023
Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine.
Wu, F., Li, X., Looso, M., Liu, H., Ding, D., Günther, S., Kuenne, C., Liu, S., Weissmann, N., Boettger, T., Atzberger, A., Kolahian, S., Renz, H., Offermanns, S., Gärtner, U., Potente, M., Zhou, Y., Yuan, X. and Braun, T.
Nature Genetics 55
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January 2023
ClC-7 drives intraphagosomal chloride accumulation to support hydrolase activity and phagosome resolution.
Wu, J.Z., Zeziulia, M., Kwon, W., Jentsch, T.J., Grinstein, S. and Freeman, S.A.
Journal of Cell Biology 222
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5 June 2023
Consistency across multi-omics layers in a drug-perturbed gut microbial community.
Wuyts, S., Alves, R., Zimmermann-Kogadeeva, M., Nishijima, S., Blasche, S., Driessen, M., Geyer, P.E, Hercog, R., Kartal, E., Maier, L., Müller, J.B., Garcia Santamarina, S., Schmidt, T.S.B., Sevin, D.C., Telzerow, A., Treit, P.V., Wenzel, T., Typas, A., Patil, K.R, Mann, M., Kuhn, M. and Bork, P.
Molecular Systems Biology 19
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12 September 2023
Prävention von Infektionskrankheiten mit Abwasser [Prevention of Infectious Diseases with Wastewater].
Wyler, E. and Landthaler, M.
Arbeitsmedizin Sozialmedizin Umweltmedizin 58
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June 2023
Maternal-derived galectin 1 shapes the placenta niche through Sda terminal glycosylation: Implication for preeclampsia.
Xie, Y., Zhao, F., Freitag, N., Borowski, S., Wang, Y., Harms, C., Pang, P.C., Desforges, J., Wen, T., Schwedhelm, E., Singh, M., Dechend, R., Dell, A., Haslam, S.M., Dveksler, G., Garcia, M.G. and Blois, S.M.
PNAS Nexus 2
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August 2023
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.
Xiong, E., Popp, O., Salomon, C., Mertins, P., Kocks, C., Rajewsky, K. and Chu, V.T.
Frontiers in Immunology 13
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5 January 2023
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Yan, S., Schöpe, P.C., Lewis, J., Putzker, K., Uhrig, U., Specker, E., von Kries, J.P., Lindemann, P., Omran, A., Sanchez-Ibarra, H.E., Unger, A., Zischinsky, M.L., Klebl, B., Walther, W., Nazaré, M., Kobelt, D. and Stein, U.
Biomedicine & Pharmacotherapy 168
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December 2023
Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction.
Yeh, Y.T., Sona, C., Yan, X., Li, Y., Pathak, A., McDermott, M.I., Xie, Z., Liu, L., Arunagiri, A., Wang, Y., Cazenave-Gassiot, A., Ghosh, A., von Meyenn, F., Kumarasamy, S., Najjar, S.M., Jia, S., Wenk, M.R., Traynor-Kaplan, A., Arvan, P., Barg, S., Bankaitis, V.A. and Poy, M.N.
Nature Communications 14
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17 July 2023
Efficient skin interactions of graphene derivatives: challenge, opportunity or both?
Zabihi, F., Tu, Z., Kaessmeyer, S., Schumacher, F., Rancan, F., Kleuser, B., Boettcher, C., Ludwig, K., Plendl, J., Hedtrich, S., Vogt, A. and Haag, R.
Nanoscale Advances 5
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7 November 2023
Response to anti-SARS-CoV-2 mRNA vaccines in multiple myeloma and chronic lymphocytic leukemia patients.
Zaleska, J., Kwasnik, P., Paziewska, M., Purkot, Jo., Szabelak, A., Jurek, M., Masny, N., Dziatkiewicz, I., Pronobis-Szczylik, B., Piebiak, A., Szymczyk, A., Jarosz-Chudzik, K., Bolkun, L., Kozlowska, K., Piszcz, J., Subocz, E., Halka, J., Bator, M., Kalicinska, E., Wrobel, T., Usnarska-Zubkiewicz, L., Rybka, J., Deren-Wagemann, I., Szyca-Smieszniak, M., Dybko, J., Hus, I., Pula, B., Cichocka, E., Rymko, M., Zdunczyk, D., Ziarkiewicz, M., Basak, G.W., Bullinger, L. and Giannopoulos, K.
International Journal of Cancer 15
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15 February 2023
Ethanol deprivation and central 5-HT deficiency differentially affect the mRNA editing of the 5-HT(2C) receptor in the mouse brain.
Zaniewska, M., Alenina, N., Fröhler, S., Chen, W. and Bader, M.
Pharmacological Reports 75
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December 2023
Association between frailty and free-living walking performance in people with multiple sclerosis.
Zanotto, T., Galperin, I., Mirelman, A., Chen, L., Regev, K., Karni, A., Schmitz-Hübsch, T., Paul, F., Lynch, S.G., Akinwuntan, A.E., Devos, H., Hausdorff, J.M. and Sosnoff, J.J.
Physical Therapy 103
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May 2023
Anwendung von „large language models“ in der Klinik [Clinical application of large language models : Does ChatGPT replace medical report formulation? An experience report].
Zernikow, J., Grassow, L., Gröschel, J., Henrion, P., Wetzel, P.J. and Spethmann, S.
Innere Medizin 64
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November 2023
Molecular basis of ClC-6 function and its impairment in human disease.
Zhang, B., Zhang, S., Polovitskaya, M.M., Yi, J., Ye, B., Li, R., Huang, X., Yin, J., Neuens, S., Balfroid, T., Soblet, J., Vens, D., Aeby, A., Li, X., Cai, J., Song, Y., Li, Y., Tartaglia, M., Li, Y., Jentsch, T.J., Yang, M. and Liu, Z.
Science Advances 9
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13 October 2023
Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19.
Zhang, B., Zhang, Z., Koeken, V.A.C.M., Kumar, S., Aillaud, M., Tsay, H.C., Liu, Z., Kraft, A.R.M., Soon, C.F., Odak, I., Bošnjak, B., Vlot, A., Swertz, M.A., Ohler, U., Geffers, R., Illig, T., Huehn, J., Saliba, A.E., Sander, L.E., Förster, R., Xu, C.J., Cornberg, M., Schulte, L.N. and Li, Y.
Cell Genomics 3
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8 February 2023
Stable isotope-assisted untargeted metabolomics identifies ALDH1A1-driven erythronate accumulation in lung cancer cells.
Zhang, J., Keibler, M.A., Dong, W., Ghelfi, J., Cordes, T., Kanashova, T., Pailot, A., Linster, C.L., Dittmar, G., Metallo, C.M., Lautenschlaeger, T., Hiller, K. and Stephanopoulos, G.
Biomedicines 11
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19 October 2023
LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cells.
Zhang, J., Sommermann, T., Li, X., Gieselmann, L., de la Rosa, K., Stecklum, M., Klein, F., Kocks, C. and Rajewsky, K.
Frontiers in Immunology 14
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19 December 2023
Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
Zhang, L., Wirth, M., Patra, U., Stroh, J., Isaakidis, K., Rieger, L., Kossatz, S., Milanovic, M., Zang, C., Demel, U., Keiten-Schmitz, J., Wagner, K., Steiger, K., Rad, R., Bassermann, F., Müller, S., Keller, U. and Schick, M.
EMBO Molecular Medicine 15
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September 2023
Assessment of rhabdomyolysis-induced acute kidney injury with chemical exchange saturation transfer magnetic resonance imaging.
Zhang, Q., Tao, Q., Xie, Y., Chen, Z., Seeliger, E., Niendorf, T., Chen, W. and Feng, Y.
Quantitative Imaging in Medicine and Surgery 13
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December 2023
Diagnostic and prognostic performance of renal compartment volume and the apparent diffusion coefficient obtained from magnetic resonance imaging in mild, moderate and severe diabetic kidney disease.
Zhao, K., Li, S., Liu, Y., Li, Q., Lin, H., Wu, Z., Seeliger, E., Niendorf, T., Liu, Z. and Wang, W.
Quantitative Imaging in Medicine and Surgery 13
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1 June 2023
miRNAs from inflamed gingiva link gene signaling to increased MET expression.
Zheng, L., Chopra, A., Weiner, J., Beule, D., Dommisch, H. and Schaefer, A.S.
Journal of Dental Research 102
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December 2023
Serotonin-induced stereospecific formation and bioactivity of the eicosanoid 17,18-epoxyeicosatetraenoic acid in the regulation of pharyngeal pumping of C. elegans.
Zhou, Y., Rothe, M., Schunck, W.H., Ruess, L. and Menzel, R.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1868
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May 2023
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.
Zhu, H., Wang, G., Nguyen-Ngoc, K.V., Kim, D., Miller, M., Goss, G., Kovsky, J., Harrington, A.R., Saunders, D.C., Hopkirk, A.L., Melton, R., Powers, A.C., Preissl, S., Spagnoli, F.M., Gaulton, K.J. and Sander, M.
Developmental Cell 58
(9): 727-743.
8 May 2023
Ablation of collagen XII disturbs joint extracellular matrix organization and causes patellar subluxation.
Zhu, M., Metzen, F., Hopkinson, M., Betz, J., Heilig, J., Sodhi, J., Imhof, T., Niehoff, A., Birk, D.E., Izu, Y., Krüger, M., Pitsillides, A. A., Altmüller, J., van Osch, G.J.V.M., Straub, V., Schreiber, G., Paulsson, M., Koch, M. and Brachvogel, B.
iScience 26
(7): 107225.
21 July 2023
Prioritization of non-coding elements involved in non-syndromic cleft lip with/without cleft palate through genome-wide analysis of de novo mutations.
Zieger, H.K., Weinhold, L., Schmidt, A., Holtgrewe, M., Juranek, S.A., Siewert, A., Scheer, A.B., Thieme, F., Mangold, E., Ishorst, N., Brand, F.U., Welzenbach, J., Beule, D., Paeschke, K., Krawitz, P.M. and Ludwig, K.U.
Human Genetics and Genomics Advances 4
(1): 100166.
12 January 2023
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
Ziegler, K.A., Ahles, A., Dueck, A., Esfandyari, D., Pichler, P., Weber, K., Kotschi, S., Bartelt, A., Sinicina, I., Graw, M., Leonhardt, H., Weckbach, L.T., Massberg, S., Schifferer, M., Simons, M., Hoeher, L., Luo, J., Ertürk, A., Schiattarella, G.G., Sassi, Y., Misgeld, T. and Engelhardt, S.
Science 381
(6655): 285-290.
21 July 2023
Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure.
Zweck, E., Karschnia, M., Scheiber, D., Heidecke, H., Dechend, R., Barthuber, C., Kaufmann, S., Kelm, M., Roden, M., Westenfeld, R., Szendrödi, J. and Boege, F.
ESC Heart Failure 10
(2): 1258-1269.
April 2023
Tumour mutational burden and survival with molecularly matched therapy.
de Bortoli, T., Benary, M., Horak, P., Lamping, M., Stintzing, S., Tinhofer, I., Leyvraz, S., Schäfer, R., Klauschen, F., Keller, U., Stenzinger, A., Fröhling, S., Kurzrock, R., Keilholz, U., Rieke, D.T. and Jelas, I.
European Journal of Cancer 190
: 112925.
September 2023
Differential ripple propagation along the hippocampal longitudinal axis.
de Filippo, R. and Schmitz, D.
eLife 12
: e85488.
13 April 2023
Pandemieforschung: von Autoantikörpern und Impfstoff-Innovationen.
de la Rosa, K.
BIOspektrum 29
(6): 614-616.
October 2023
Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease.
van Kraaij, S.J.W., Pereira, D.R., Smal, B., Summo, L., Konkel, A., Lossie, J., Busjahn, A., Grammatopoulos, T.N., Klaassen, E., Fischer, R., Schunck, W.H., Gal, P. and Moerland, M.
Clinical and Translational Science 16
(7): 1258-1271.
July 2023
The phenotypic and genotypic spectrum of epilepsy and intellectual disability in adults: Implications for genetic testing.
von Brauchitsch, S., Haslinger, D., Lindlar, S., Thiele, H., Bernsen, N., Zahnert, F., Reif, P.S., Balcik, Y., Au, P.Y.B., Josephson, C., Altmüller, J., Strzelczyk, A., Knake, S., Rosenow, F., Chiocchetti, A. and Klein, K.M.
Epilepsia Open 8
(2): 497-508.
June 2023
Citizen science’s transformative impact on science, citizen empowerment and socio-political processes.
von Gönner, J., Herrmann, T.M., Bruckermann, T., Eichinger, M., Hecker, S., Klan, F., Lorke, J., Richter, A., Sturm, U., Voigt-Heucke, S., Brink, W., Liedtke, C., Premke-Kraus, M., Altmann, C., Bauhus, W., Bengtsson, L., Büermann, A., Dietrich, P., Dörler, D., Eich-Brod, R., Ferschinger, L., Freyberg, L., Grützner, A., Hammel, G., Heigl, F., Heyen, N.B., Hölker, F., Johannsen, C., Kluß, T., Kluttig, T., Knobloch, J., Munke, M., Mortega, K., Pathe, C., Soßdorf, A., Stämpfli, T., Thiel, C., Tönsmann, S., Valentin, A., Wagenknecht, K., Wegener, R., Woll, S. and Bonn, A.
Socio-Ecological Practice Research 5
: 11-33.
March 2023
Increased flexibility of brain dynamics in patients with multiple sclerosis.
von Schwanenflug, N., Koch, S.P., Krohn, S., Broeders, T.A.A., Lydon-Staley, D.M., Bassett, D.S., Schoonheim, M.M., Paul, F. and Finke, C.
Brain Communications 5
(3): fcad143.
3 May 2023
Biliary microbial patterns in primary sclerosing cholangitis are linked to poorer transplant-free survival.
Özdirik, B., Scherf, M., Brumercek, A., Nicklaus, J.M., Kruis, T., Haber, P.K., Pratschke, J., Tacke, F. and Sigal, M.
Hepatology Communications 7
(6): e0156.
June 2023
Book Section
Transgenic animal models for the functional analysis of ACE2.
Alenina, N. and Bader, M.
In:
Angiotensin : from the kidney to coronavirus.
Molecular Mediators in Health and Disease: How Cells Communicate
.
Elsevier / Academic Press, London, 491-503.
ISBN 978-0-323-99618-1
2023
Therapien zum Zellersatz mit adulten Stammzelltypen.
Besser, D., Bönig, H.B., Giebel, B., Klump, H. and Spuler, S.
In:
Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft.
Springer, Berlin, Heidelberg, Germany, 217-232.
ISBN 978-3-662-67908-1
30 December 2023
Bioactive phytochemicals from avocado oil processing by-products.
Cárdenas-Castro, A.P., Fernández-Ochoa, Á., Cádiz-Gurrea, M.d.l.L., Segura Carretero, A. and Sáyago-Ayerdi, S.G.
In:
Bioactive phytochemicals from vegetable oil and oilseed processing by-products.
Reference Series in Phytochemistry, 1
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Springer, Cham, Switzerland, 403-430.
ISBN 978-3-030-91380-9
22 March 2023
Mechanistic insights into T-Cell antigen recognition through single molecule microscopy.
Huppa, J.B. and Schütz, G.J.
In:
Encyclopedia of Cell Biology.
Encyclopedia of Cell Biology, 5
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Elsevier, 536-552.
ISBN 978-0-12-821624-8
2023
ANCA-Vaskulitis.
Kettritz, R.
In:
DGIM Innere Medizin.
Springer Reference Medizin (SRM)
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Springer, Berlin, Heidelberg, Germany, 1-3.
22 August 2023
Nierenbeteiligung bei Systemerkrankungen.
Kettritz, R.
In:
Geriatrische Nephrologie.
Springer, Berlin, Heidelberg, 153-161.
ISBN 978-3-662-65647-1
2023
Infectious cardiac diseases in children.
Klaassen, S., Seidel, F., Dalinghaus, M., Salaets, T. and Heying, R.
In:
Pediatric cardiology: fetal, pediatric, and adult congenital heart diseases.
Springer, Cham, 1-31.
ISBN 978-3-030-42937-9
30 September 2023
Infectious cardiac diseases in children; Sabine Klaassen, Franziska Seidel, Michiel Dalinghaus, Thomas Salaets, Ruth Heying.
Klaassen, S., Seidel, F., Dalinghaus, M., Salaets, T. and Heying, R.
In:
Pediatric cardiology : fetal, pediatric, and adult congenital heart diseases.
Springer, Cham.
ISBN 978-3-030-42937-9
21 July 2023
Bioactive phytochemicals from sesame oil processing by-products.
Mekky, R.H., Hegazy, M.M., Cádiz-Gurrea, M.d.l.L., Fernández-Ochoa, Á. and Segura Carretero, A.
In:
Bioactive phytochemicals from vegetable oil and oilseed processing by-products.
Reference Series in Phytochemistry, 1
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Springer, Cham, Switzerland, 155-194.
ISBN 978-3-030-91380-9
22 March 2023
Probing renal oxygenation with T2*-sensitized MRI (BOLD-MRI).
Mendichovszky, I.A., Milani, B., Li, L.P., Niendorf, T., Pruijm, M. and Prasad, P.V.
In:
Advanced clinical MRI of the kidney : methods and protocols.
Springer, Cham, 133-151.
ISBN 978-3-031-40168-8
18 November 2023
Pathophysiology and differentiation from other symptoms and diseasess.
Paul, F.
In:
Fatigue in Multiple Sclerosis.
Springer, Cham, 27-39.
ISBN 978-3-031-13497-5
2 January 2023
Multiple Sklerose.
Seifert, R. and Paul, F.
In:
Arzneiverordnungs-Report 2022.
Springer, Berlin, Heidelberg, 497-517.
ISBN 978-3-662-66302-8
3 February 2023
Conference or Workshop Item
Towards hierarchical regional transformer-based multiple instance learning.
Cersovsky, J., Mohammadi, S., Kainmueller, D. and Hoehne, J.
In: 2023 IEEE/CVF International Conference on Computer Vision Workshops (ICCVW), 02-06 Oct 2023, Paris, France.
25 December 2023
Quantitative morphological analysis of the T-tubular network of ventricular cardiomyocytes using novel image processing tools.
Georgoula, K., Sage, D. and Annibale, P.
In: European Conferences on Biomedical Optics 2023, 25-29 June 2023, Munich, Germany.
11 August 2023
ACTIS: improving data efficiency by leveraging semi-supervised augmentation consistency training for instance segmentation.
Rumberger, J.L., Franzen, J., Hirsch, P., Albrecht, J.P. and Kainmueller, D.
In: 2023 IEEE/CVF International Conference on Computer Vision Workshops (ICCVW), 02-06 Oct 2023, Paris, France.
25 December 2023
Short and long-term photostability of 3D printed fluorescent phantoms for near-infrared diffuse optical imaging.
Schädel-Ebner, Sandra, Hirsch, Ole, Gladytz, T., Gutkelch, Dirk, Licha, Kai, Berger, Jörn and Grosenick, Dirk
In: European Conferences on Biomedical Optics 2017, 25-29 June 2023, Munich, Germany.
9 August 2023
Patent
Gene editing to improve pancreatic beta cell yield in directed differentiation of human pluripotent stem cells.
The regents of the university of California.
WO-2023137235-A3.
20 July 2023
New MERS-CoV Vaccine.
Max Delbrueck Centrum fuer Molekulare in der Helmholtz Gemeinschaft.
22164013.9.
27 September 2023
Review
Evolution of 3D chromatin organization at different scales.
Acemel, R.D. and Lupianez, D.G.
Current Opinion in Genetics & Development 78
: 102019.
February 2023
Cephalopod-omics: emerging fields and technologies in cephalopod biology.
Baden, T., Briseño, J., Coffing, G., Cohen-Bodénès, S., Courtney, A., Dickerson, D., Dölen, G., Fiorito, G., Gestal, C., Gustafson, T., Heath-Heckman, E., Hua, Q., Imperadore, P., Kimbara, R., Król, M., Lajbner, Z., Lichilín, N., Macchi, F., McCoy, M.J., Nishiguchi, M.K., Nyholm, S.V., Otjacques, E., Pérez-Ferrer, P.A., Ponte, G., Pungor, J.R., Rogers, T.F., Rosenthal, J.J.C., Rouressol, L., Rubas, N., Sanchez, G., Santos, C.P., Schultz, D.T., Seuntjens, E., Songco-Casey, J.O., Stewart, I.E., Styfhals, R., Tuanapaya, S., Vijayan, N., Weissenbacher, A., Zifcakova, L., Schulz, G., Weertman, W., Simakov, O. and Albertin, C.
Integrative and Comparative Biology 63
(6): 1226-1239.
December 2023
Renal MRI: from nephron to NMR signal.
Bane, O., Seeliger, E., Cox, E., Stabinska, J., Bechler, E., Lewis, S., Hickson, L.T.J., Francis, S., Sigmund, E. and Niendorf, T.
Journal of Magnetic Resonance Imaging 58
(6): 1660-1679.
December 2023
Unwelcome guests – the role of gland-associated Helicobacter pylori infection in gastric carcinogenesis.
Beccaceci, G. and Sigal, M.
Frontiers in Oncology 13
: 1171003.
21 April 2023
Towards monitoring of antimicrobial resistance in the environment: For what reasons, how to implement it, and what are the data needs?
Bengtsson-Palme, J., Abramova, A., Berendonk, T.U., Coelho, L.P., Forslund, S.K., Gschwind, R., Heikinheimo, A., Jarquín-Díaz, V.H., Khan, A.A., Klümper, U., Löber, U., Nekoro, M., Osińska, A.D., Ugarcina Perovic, S., Pitkänen, T., Rødland, E.K., Ruppé, E., Wasteson, Y., Wester, A.L. and Zahra, R.
Environment International 178
: 108089.
5 July 2023
A review on multiple sclerosis prognostic findings from imaging, inflammation, and mental health studies.
Brasanac, J. and Chien, C.
Frontiers in Human Neuroscience 17
: 1151531.
11 May 2023
Current practices in lc-ms untargeted metabolomics: a scoping review on the use of pooled quality control samples.
Broeckling, C.D., Beger, R.D., Cheng, L.L., Cumeras, R., Cuthbertson, D.J., Dasari, S., Davis, W.C., Dunn, W.B., Evans, A.M., Fernández-Ochoa, Á., Gika, H., Goodacre, R., Goodman, K.D., Gouveia, G.J., Hsu, P.C., Kirwan, J.A., Kodra, D., Kuligowski, J., Lan, R.S.L., Monge, M.E., Moussa, L.W., Nair, S.G., Reisdorph, N., Sherrod, S.D., Ulmer Holland, C., Vuckovic, D., Yu, L.R., Zhang, B., Theodoridis, G. and Mosley, J.D.
Analytical Chemistry 95
(51): 18645-18654.
26 December 2023
Evolution and implications of de novo genes in humans.
Broeils, L.A., Ruiz-Orera, J., Snel, B., Hubner, N. and van Heesch, S.
Nature Ecology & Evolution 7
(6): 804-815.
June 2023
MRI to differentiate multiple sclerosis, neuromyelitis optica, and myelin oligodendrocyte glycoprotein antibody disease.
Carnero Contentti, E., Okuda, D.T., Rojas, J.I., Chien, C., Paul, F. and Alonso, R.
Journal of Neuroimaging 33
(5): 688-702.
September 2023
Dipeptidyl peptidase 1 inhibition as a potential therapeutic approach in neutrophil-mediated inflammatory disease.
Chalmers, J.D., Kettritz, R. and Korkmaz, B.
Frontiers in Immunology 14
: 1239151.
14 December 2023
Mechanisms of substrate processing during ER-associated protein degradation.
Christianson, J.C., Jarosch, E. and Sommer, T.
Nature Reviews Molecular Cell Biology 24
(11): 777-796.
November 2023
Mesoangioblasts at 20: from the embryonic aorta to the patient bed.
Cossu, G., Tonlorenzi, R., Brunelli, S., Sampaolesi, M., Messina, G., Azzoni, E., Benedetti, S., Biressi, S., Bonfanti, C., Bragg, L., Camps, J., Cappellari, O., Cassano, M., Ciceri, F., Coletta, M., Covarello, D., Crippa, S., Cusella-De Angelis, M.G., De Angelis, L., Dellavalle, A., Diaz-Manera, J., Galli, D., Galli, F., Gargioli, C., Gerli, M.F.M., Giacomazzi, G., Galvez, B.G., Hoshiya, H., Guttinger, M., Innocenzi, A., Minasi, M.G., Perani, L., Previtali, S.C., Quattrocelli, M., Ragazzi, M., Roostalu, U., Rossi, G., Scardigli, R., Sirabella, D., Tedesco, F.S., Torrente, Y. and Ugarte, G.
Frontiers in Genetics 13
: 1056114.
4 January 2023
Arterial myogenic response and aging.
Cui, Y., Gollasch, M. and Kassmann, M.
Ageing Research Reviews 84
: 101813.
February 2023
Targeting B cells and microglia in multiple sclerosis with Bruton tyrosine kinase inhibitors: a review.
Dybowski, S., Torke, S. and Weber, M.S.
JAMA Neurology 80
(4): 404-414.
1 April 2023
Diverse effects of obesity on antitumor immunity and immunotherapy.
Dyck, L. and Lynch, L.
Trends in Molecular Medicine 29
(2): 112-123.
February 2023
Genome-engineering technologies for modeling and treatment of cystic fibrosis.
Dębczyński, M., Mojsak, D., Minarowski, Ł., Maciejewska, M., Lisowski, P. and Mróz, R.M.
Advances in Medical Sciences 68
(1): 111-120.
March 2023
Mutations in phosphodiesterase 3A (PDE3A) cause hypertension without cardiac damage.
Ercu, M., Walter, S. and Klussmann, E.
Hypertension 80
(6): 1171-1179.
June 2023
Stellenwert der kardialen MRT bei Patienten mit ventrikulären Arrhythmien und zur Prävention des plötzlichen Herztods [Role of cardiovascular MRI in patients with ventricular arrhythmias and prevention of sudden cardiac death].
Fenski, M., Krüger, L.D. and Schulz-Menger, J.
Aktuelle Kardiologie 12
(03): 199-206.
6 June 2023
Cardiovascular magnetic resonance for evaluation of cardiac involvement in COVID-19: recommendations by the Society for Cardiovascular Magnetic Resonance.
Ferreira, V.M., Plein, S., Wong, T.C., Tao, Q., Raisi-Estabragh, Z., Jain, S.S., Han, Y., Ojha, V., Bluemke, D.A., Hanneman, K., Weinsaft, J., Vidula, M.K., Ntusi, N. A.B., Schulz-Menger, J. and Kim, J.
Journal of Cardiovascular Magnetic Resonance 25
(1): 21.
27 March 2023
Heart development and regeneration -- a multi‐organ effort.
Filosa, A. and Sawamiphak, S.
FEBS Journal 290
(4): 913-930.
February 2023
The thalamus in perioperative neurocognitive disorders.
Fislage, M., Zacharias, N. and Feinkohl, I.
Neuropsychology Review 34
(3): 850-859.
September 2023
Fasting intervention and its clinical effects on the human host and microbiome.
Forslund, S.K.
Journal of Internal Medicine 293
(2): 166-183.
February 2023
Protein biomarkers in blood reflect the interrelationships between stroke outcome, inflammation, coagulation, adhesion, senescence and cancer.
Fuellen, G., Walter, U., Henze, L., Böhmert, J., Palmer, D., Lee, S., Schmitt, C.A., Rudolf, H. and Kowald, A.
Cellular and Molecular Neurobiology 43
(4): 1413-1424.
May 2023
The effect of probiotic and synbiotic supplementation on lipid parameters among patients with cardiometabolic risk factors: a systematic review and meta-analysis of clinical trials.
Ghorbani, Z., Kazemi, A., Bartolomaeus, T.U.P., Martami, F., Noormohammadi, M., Salari, A., Löber, U., Balou, H.A., Forslund, S.K. and Mahdavi-Roshan, M.
Cardiovascular Research 119
(4): 933-956.
April 2023
Cardiac splicing as a diagnostic and therapeutic target.
Gotthardt, M., Badillo Lisakowski, V., Parikh, V.N., Ashley, E., Furtado, M., Carmo-Fonseca, M., Schudy, S., Meder, B., Grosch, M., Steinmetz, L., Crocini, C. and Leinwand, L.
Nature Reviews Cardiology 20
(8): 517-530.
August 2023
Proteostasis in T cell aging.
Gressler, A.E., Leng, H., Zinecker, H. and Simon, A.K.
Seminars in Immunology 70
: 101838.
November 2023
Long COVID and the cardiovascular system - elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint
Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial & Pericardial Diseases.
Gyöngyösi, M., Alcaide, P., Asselbergs, F.W., Brundel, B.J.J.M., Camici, G.G., da Costa Martins, P., Ferdinandy, P., Fontana, M., Girao, H., Gnecchi, M., Gollmann-Tepeköylü, C., Kleinbongard, P., Krieg, T., Madonna, R., Paillard, M., Pantazis, A., Perrino, C., Pesce, M., Schiattarella, G.G., Sluijter, J.P.G., Steffens, S., Tschöpe, C., Van Linthout, S. and Davidson, S.M.
Cardiovascular Research 119
(2): 336-356.
February 2023
Single-cell multi-omics and lineage tracing to dissect cell fate decision-making.
Haghverdi, L. and Ludwig, L.S.
Stem Cell Reports 18
(1): 13-25.
10 January 2023
Ten simple rules for implementing open and reproducible research practices after attending a training course.
Heise, V., Holman, C., Lo, H., Lyras, E.M., Adkins, M.C., Aquino, M.R.J., Bougioukas, K.I., Bray, K.O., Gajos, M., Guo, X., Hartling, C., Huerta-Gutierrez, R., Jindrová, M., Kenney, J.P.M., Kępińska, A.P., Kneller, L., Lopez-Rodriguez, E., Mühlensiepen, F., Richards, A., Richards, G., Siebert, M., Smith, J.A., Smith, N., Stransky, N., Tarvainen, S., Valdes, D.S., Warrington, K.L., Wilpert, N.M., Witkowska, D., Zaneva, M., Zanker, J. and Weissgerber, T.L.
PLoS Computational Biology 19
(1): e1010750.
5 January 2023
Recent advances in precision medicine for acute myeloid leukemia.
Hernández-Sánchez, A. and Bullinger, L.
Current Opinion in Oncology 35
(6): 581-588.
November 2023
Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis.
Jarius, S., Aktas, O., Ayzenberg, I., Bellmann-Strobl, J., Berthele, A., Giglhuber, K., Häußler, V., Havla, J., Hellwig, K., Hümmert, M.W., Kleiter, I., Klotz, L., Krumbholz, M., Kümpfel, T., Paul, F., Ringelstein, M., Ruprecht, K., Senel, M., Stellmann, J.P., Bergh, F.T., Tumani, H., Wildemann, B. and Trebst, C.
Journal of Neurology 270
(7): 3341-3368.
July 2023
DNA repair and antibody diversification: the 53BP1 paradigm.
Kabrani, E., Saha, T. and Di Virgilio, M.
Trends in Immunology 44
(10): 782-791.
October 2023
Airway microbiome-immune crosstalk in chronic obstructive pulmonary disease.
Kayongo, A., Robertson, N.M., Siddharthan, T., Ntayi, M.L., Ndawula, J.C., Sande, O.J., Bagaya, B.S., Kirenga, B., Mayanja-Kizza, H., Joloba, M.L. and Forslund, S.K.
Frontiers in Immunology 13
: 1085551.
17 January 2023
The central role of DNA damage in immunosenescence.
Kell, L., Simon, A.K., Alsaleh, G. and Cox, L.S.
Frontiers in Aging 4
: 1202152.
3 July 2023
Potassium homeostasis - Physiology and pharmacology in a clinical context.
Kettritz, R. and Loffing, J.
Pharmacology & Therapeutics 249
: 108489.
September 2023
Many kinases for controlling the water channel aquaporin‐2.
Kharin, A. and Klussmann, E.
Journal of Physiology 602
(13): 3025-3039.
1 July 2023
Eleven strategies for making reproducible research and open science training the norm at research institutions.
Kohrs, F.E., Auer, S., Bannach-Brown, A., Fiedler, S., Haven, T.L., Heise, V., Holman, C., Azevedo, F., Bernard, R., Bleier, A., Bössel, N., Cahill, B.P., Castro, L.J., Ehrenhofer, A., Eichel, K., Frank, M., Frick, C., Friese, M., Gärtner, A., Gierend, K., Grüning, D.J., Hahn, L., Hülsemann, M., Ihle, M., Illius, S., König, L., König, M., Kulke, L., Kutlin, A., Lammers, F., Mehler, D.M.A., Miehl, C., Müller-Alcazar, A., Neuendorf, C., Niemeyer, H., Pargent, F., Peikert, A., Pfeuffer, C.U., Reinecke, R., Röer, J.P., Rohmann, J.L., Sánchez-Tójar, A., Scherbaum, S., Sixtus, E., Spitzer, L., Straßburger, V.M., Weber, M., Whitmire, C.J., Zerna, J., Zorbek, D., Zumstein, P. and Weissgerber, T.L.
eLife 12
: e89736.
23 November 2023
Germany's journey toward 14 Tesla human magnetic resonance.
Ladd, M.E., Quick, H.H., Speck, O., Bock, M., Doerfler, A., Forsting, M., Hennig, J., Ittermann, B., Möller, H.E., Nagel, A.M., Niendorf, T., Remy, S., Schaeffter, T., Scheffler, K., Schlemmer, H.P., Schmitter, S., Schreiber, L., Shah, N.J., Stöcker, T., Uder, M., Villringer, A., Weiskopf, N., Zaiss, M. and Zaitsev, M.
Magnetic Resonance Materials in Physics Biology and Medicine 36
(2): 191-210.
April 2023
Mechanisms of resistance to small molecules in acute myeloid leukemia.
Lang, T.J.L., Damm, F., Bullinger, L. and Frick, M.
Cancers 15
(18): 4573.
15 September 2023
Thermosensory thalamus: parallel processing across model organisms.
Leva, T. and Whitmire, C.
Frontiers in Neuroscience 17
: 1210949.
13 October 2023
Human disease models in drug development.
Loewa, A., Feng, J.J. and Hedtrich, S.
Nature Reviews Bioengineering
11 May 2023
(In Press)
Sixty years of confronting diabetes and kidney disease.
Luft, F.C.
Seminars in Nephrology 43
(3): 151426.
May 2023
Single-cell transcriptomics for the assessment of cardiac disease.
Miranda, A.M.A., Janbandhu, V., Maatz, H., Kanemaru, K., Cranley, J., Teichmann, S.A., Huebner, N., Schneider, M.D., Harvey, R.P. and Noseda, M.
Nature Reviews Cardiology 20
(5): 289-308.
May 2023
Optical coherence tomography angiography measurements in multiple sclerosis: a systematic review and meta-analysis.
Mohammadi, S., Gouravani, M., Salehi, M.A., Arevalo, J.F., Galetta, S.L., Harandi, H., Frohman, E.M., Frohman, T.C., Saidha, S., Sattarnezhad, N. and Paul, F.
Journal of Neuroinflammation 20
(1): 85.
27 March 2023
Toward identification of functional sequences and variants in noncoding DNA.
Monti, R. and Ohler, U.
Annual Review of Biomedical Data Science 6
: 191-210.
August 2023
High-throughput metabolomics applications in pathogenesis and diagnosis of valvular heart disease.
Mutithu, D.W., Kirwan, J.A., Adeola, H.A., Aremu, O.O., Lumngwena, E.N., Wiesner, L., Skatulla, S., Naidoo, R. and Ntusi, N.A.B.
Reviews in Cardiovascular Medicine 24
(6): 169.
June 2023
Instrumental drift in untargeted metabolomics: optimizing data quality with intrastudy QC samples.
Märtens, A., Holle, J., Mollenhauer, B., Wegner, A., Kirwan, J. and Hiller, K.
Metabolites 13
(5): 665.
16 May 2023
The effect of probiotic and synbiotic supplementation on appetite-regulating hormones and desire to eat: a systematic review and meta-analysis of clinical trials.
Noormohammadi, M., Ghorbani, Z., Löber, U., Mahdavi-Roshan, M., Bartolomaeus, T.U.P., Kazemi, A., Shoaibinobarian, N. and Forslund, S.K.
Pharmacological Research 187
: 106614.
January 2023
Delimiting MOGAD as a disease entity using translational imaging.
Oertel, F.C., Hastermann, M. and Paul, F.
Frontiers in Neurology 14
: 1216477.
7 December 2023
Roles of cholesterol and PtdIns(4,5)P(2) in the regulation of STIM1-Orai1 channel function.
Pacheco, J., Bohórquez-Hernández, A., Méndez-Acevedo, K.M., Sampieri, A. and Vaca, L.
Advances in Experimental Medicine and Biology 1422
: 305-326.
2023
Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
Pearson, A.D.J., Federico, S., Gatz, S.A., Ortiz, M., Lesa, G., Scobie, N., Gounaris, I., Weiner, S.L., Weigel, B., Unger, T.J., Stewart, E., Smith, M., Slotkin, E.K., Reaman, G., Pappo, A., Nysom, K., Norga, K., McDonough, J., Marshall, L.V., Ludwinski, D., Ligas, F., Karres, D., Kool, M., Horner, T.J., Henssen, A., Heenen, D., Hawkins, D.S., Gore, L., Bender, J.G., Galluzzo, S., Fox, E., de Rojas, T., Davies, B.R., Chakrabarti, J., Carmichael, J., Bradford, D., Blanc, P., Bernardi, R., Benchetrit, S., Akindele, K. and Vassal, G.
European Journal of Cancer 190
: 112950.
September 2023
Autophagy orchestrates the crosstalk between cells and organs.
Piletic, K., Alsaleh, G. and Simon, A.K.
EMBO Reports 24
(9): e57289.
6 September 2023
Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease.
Piwecka, M., Rajewsky, N. and Rybak-Wolf, A.
Nature Reviews Neurology 19
(6): 346–362.
June 2023
The IgSF cell adhesion protein CLMP and congenital short bowel syndrome (CSBS).
Rathjen, F.G. and Jüttner, R.
International Journal of Molecular Sciences 24
(6): 5719.
16 March 2023
Protein intake and risk of urolithiasis and kidney diseases: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society.
Remer, T., Kalotai, N., Amini, A.M., Lehmann, A., Schmidt, A., Bischoff-Ferrari, H.A., Egert, S., Ellinger, S., Kroke, A., Kühn, T., Lorkowski, S., Nimptsch, K., Schwingshackl, L., Zittermann, A., Watzl, B. and Siener, R.
European Journal of Nutrition 62
(5): 1957-1975.
August 2023
The lure of cardiac metabolism in the diagnosis, prevention, and treatment of heart failure.
Rodolico, D., Schiattarella, G.G. and Taegtmeyer, H.
JACC: Heart Failure 11
(6): 637-645.
June 2023
The contribution of the AT1 receptor to erythropoiesis.
Rodrigues, A.F. and Bader, M.
Biochemical Pharmacology 217
: 115805.
November 2023
Curvature in biological systems: its quantification, emergence and implications across the scales.
Schamberger, B., Roschger, A., Ziege, R., Anselme, K., Amar, M.B., Bykowski, M., Castro, A.P.G., Cipitria, A., Coles, R., Dimova, R., Eder, M., Ehrig, S., Escudero, L.M., Evans, M.E., Fernandes, P.R., Fratzl, P., Geris, L., Gierlinger, N., Hannezo, E., Iglič, A., Kirkensgaard, J.J.K., Kollmannsberger, P., Kowalewska, Ł., Kurniawan, N.A., Papantoniou, I., Pieuchot, L., Pires, T.H.V., Renner, L., Sageman-Furnas, A., Schröder-Turk, G.E., Sengupta, A., Sharma, V.R., Tagua, A., Tomba, C., Trepat, X., Waters, S.L., Yeo, E., Bidan, C.M. and Dunlop, J.W.C.
Advanced Materials 35
(13): e2206110.
15 March 2023
Glial fibrillary acidic protein as a biomarker in neuromyelitis optica spectrum disorder: a current review.
Schindler, P., Aktas, O., Ringelstein, M., Wildemann, B., Jarius, S., Paul, F. and Ruprecht, K.
Expert Review of Clinical Immunology 19
(1): 71-91.
January 2023
Gendiagnostik bei kardiovaskulären Erkrankungen.
Schulze-Bahr, E., Klaassen, S., Gerull, B., von Kodolitsch, Y., Landmesser, U., Rieß, O., Meder, B. and Schunkert, H.
Kardiologie 17
: 300-349.
September 2023
A concise guide to choosing suitable gene expression systems for recombinant protein production.
Schütz, A., Bernhard, F., Berrow, N., Buyel, J.F., Ferreira-da-Silva, F., Haustraete, J., van den Heuvel, J., Hoffmann, J.E., de Marco, A., Peleg, Y., Suppmann, S., Unger, T., Vanhoucke, M., Witt, S. and Remans, K.
STAR Protocols 4
(4): 102572.
15 December 2023
Women physicians in cardiovascular magnetic resonance: past, present, and future.
Sierra-Galan, L.M., Aggarwal, N.R., Stojanovska, J., Raman, S.V., Han, Y., Ferreira, V.M., Thomas, K., Seiberlich, N., Parwani, P., Bucciarelli-Ducci, C., Baldassarre, L.A., Mavrogeni, S., Ordovas, K., Schulz-Menger, J. and Bandettini, W.P.
Frontiers in Cardiovascular Medicine 9
: 984326.
4 January 2023
Diastolische Dysfunktion und HFpEF bei CKD: Ein Update [Diastolic dysfunction and HFpEF in CKD: An update].
Szijártó, I.A. and Wilck, N.
Nephrologie 18
: 361–369.
November 2023
Hippocampal GABAergic interneurons and memory.
Tzilivaki, A., Tukker, J.J., Maier, N., Poirazi, P., Sammons, R.P. and Schmitz, D.
Neuron 111
(20): 3154-3175.
18 October 2023
Getting to the root of branched ubiquitin chains: a review of current methods and functions.
Waltho, A. and Sommer, T.
Methods in Molecular Biology 2602
: 19-38.
2023
Mechanisms of enhancer function in neuronal systems in health and disease.
Zea Redondo, L. and Pombo, A.
Current Opinion in Systems Biology 32-33
: 100443.
March 2023
The making of a proprioceptor: a tale of two identities.
de Nooij, J.C. and Zampieri, N.
Trends in Neurosciences 46
(12): 1083-1094.
December 2023
Cardiovascular magnetic resonance in the guidelines of the European Society of Cardiology: a comprehensive summary and update.
von Knobelsdorff-Brenkenhoff, F. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 25
(1): 42.
24 July 2023
Letter
Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda et al.
Immisch, L., Papafotiou, G., Popp, O., Mertins, P., Blankenstein, T. and Willimsky, G.
Journal for ImmunoTherapy of Cancer 11
(3): e006784.
14 March 2023
The DNA methylation status of the TERT promoter differs between subtypes of mature B-cell lymphomas.
Kouroukli, A.G., Fischer, A., Kretzmer, H., Chteinberg, E., Rajaram, N., Glaser, S., Kolarova, J., Bashtrykov, P., Mathas, S., Drexler, H.G., Ohno, H., Ammerpohl, O., Jeltsch, A., Siebert, R. and Bens, S.
Blood Cancer Journal 13
(1): 98.
26 June 2023
Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B cell impairment and increases the risk for infections - a retrospective matched cohort study.
Launspach, M., Temel, D., Ohlendorf, E., Zirngibl, F., Materne, B., Oevermann, L., Deubzer, H.E., Henssen, A.G., Künkele, A., Hundsdörfer, P., von Bernuth, H., Pruß, A., Eggert, A., von Stackelberg, A., Lang, P. and Schulte, J.H.
Haematologica 108
(1): 267-272.
January 2023
Comment to the article: "Consensus statement on the definition of orthostatic hypertension endorsed by the American Autonomic Society and the Japanese Society of Hypertension" by Jordan and colleagues.
Moreno Velásquez, L. and Pischon, T.
Clinical Autonomic Research 33
(1): 75-76.
February 2023
Comments on the myPACE randomized clinical trial.
Rodolico, D. and Schiattarella, G.G.
JAMA Cardiology 8
(8): 794-795.
August 2023
Mutant phosphodiesterase 3A protects the kidney from hypertension-induced damage.
Sholokh, A., Walter, S., Markó, L., McMurray, B.J., Sunaga-Franze, D.Y., Xu, M., Zühlke, K., Russwurm, M., Bartolomaeus, T.U.P., Langanki, R., Qadri, F., Heuser, A., Patzak, A., Forslund, S.K., Bähring, S., Borodina, T., Persson, P.B., Maass, P.G., Bader, M. and Klussmann, E.
Kidney International 104
(2): 388-393.
August 2023
Editorial
Regulation of developmental tempo in different vertebrate species.
Birchmeier, C.
Cell Stem Cell 30
(7): 907-908.
6 July 2023
Cardiovascular peptide hormones - special edition.
Braga, T.V., Mervaala, E., Santos, R. and Bader, M.
Peptides 167
: 171062.
September 2023
Cardiometabolic HFpEF: NASH of the heart.
Capone, F., Vettor, Roberto and Schiattarella, G.G.
Circulation 147
(6): 451-453.
7 February 2023
Disentangling extrachromosomal circular DNA heterogeneity in single cells with scEC&T-seq.
Chamorro González, R. and Henssen, A.G.
Nature Genetics 55
(5): 740-741.
May 2023
First demonstration of miRNA-dependent mRNA decay.
Chekulaeva, M.
Nature Reviews Molecular Cell Biology 24
(3): 164.
March 2023
A guide to naming eukaryotic circular RNAs.
Chen, L.L., Bindereif, A., Bozzoni, I., Chang, H.Y., Matera, A.G., Gorospe, M., Hansen, T.B., Kjems, J., Ma, X.K., Pek, J.W., Rajewsky, N., Salzman, J., Wilusz, J.E., Yang, L. and Zhao, F.
Nature Cell Biology 25
(1): 1-5.
January 2023
Gentle ions for cryo-FIB milling.
Chu, X. and Kudryashev, M.
Structure 31
(10): 1147-1148.
5 October 2023
N2 year in review.
Dalmau, J., Dalakas, M.C., Kolson, D.L., Paul, F., Sánchez-Valle, R. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 10
(1): e200076.
January 2023
Mucosa-associated microbiota alterations in primary sclerosing cholangitis (PSC) before and after liver transplantation—who is calling the shots?
Demir, M. and Sigal, M.
Hepatobiliary Surgery and Nutrition 12
(5): 795-797.
1 October 2023
T-cell antigen recognition: catch-as-catch-can or catch-22?
Huppa, J.B. and Schütz, G.J.
EMBO Journal 42
(7): e113507.
3 April 2023
Genetics-diet crossroads: Unveiling new insights into hypertrophic cardiomyopathy.
Häseli, S.P. and Schiattarella, G.
Journal of Molecular and Cellular Cardiology Plus 6
: 100051.
December 2023
Aquaporin-2 is not alone.
Klussmann, E.
Kidney International 103
(3): 458-460.
March 2023
Human embryo models: unveiling sophisticated self-organization of stem cells during post-implantation stages.
Lin, M. and Sigal, M.
Signal Transduction and Targeted Therapy 8
(1): 419.
6 November 2023
Kinins: Locally formed peptides during inflammation with potential use in tissue regeneration.
Martins, L., Bader, M. and Pesquero, J.B.
Inflammation Research 72
(10-11): 1957-1963.
November 2023
Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases: workshop proceedings.
Mastracci, T.L., Apte, M., Amundadottir, L.T., Alvarsson, A., Artandi, S., Bellin, M.D., Bernal-Mizrachi, E., Caicedo, A., Campbell-Thompson, M., Cruz-Monserrate, Z., El Ouaamari, A., Gaulton, K.J., Geisz, A., Goodarzi, M.O., Hara, M., Hull-Meichle, R.L., Kleger, A., Klein, A.P., Kopp, J.L., Kulkarni, R.N., Muzumdar, M.D., Naren, A.P., Oakes, S.A., Olesen, S.S., Phelps, E.A., Powers, A.C., Stabler, C.L., Tirkes, T., Whitcomb, D.C., Yadav, D., Yong, Jing, Zaghloul, N.A., Pandol, S.J. and Sander, M.
Diabetes 72
(4): 433-448.
April 2023
Salt sensitivity includes effects on immune cell signalling and metabolism.
Müller, D.N., Geisberger, S., Kleinewietfeld, M. and Jantsch, J.
Nature Reviews Immunology 23
(6): 341-342.
June 2023
Complicated monkeypox infection in a patient with multiple sclerosis and fingolimod treatment.
Müller-Jensen, L., Kriedemann, H., Anvari, K., Huehnchen, P. and Siffrin, V.
Neurology 100
(14): 670-671.
4 April 2023
Editorial: Modulation of human immune parameters by anticancer therapies, volume II.
Na, I.K., Sack, U. and Sánchez-Ramón, S.
Frontiers in Immunology 14
: 1249099.
26 July 2023
Retinal changes after acute and late optic neuritis in aquaporin-4 antibody seropositive NMOSD.
Oertel, F.C., Zimmermann, H.G., Motamedi, S., Bereuter, C., Asseyer, E.S., Chien, C., Marignier, R., Cobo-Calvo, A., Leocani, L., Pisa, M., Radaelli, M., Villoslada, P., Sanchez-Dalmau, B., Martinez-Lapiscina, E.H., Lana-Peixoto, M.A., Fontenelle, M.A., Aktas, O., Ringelstein, M., Albrecht, P., Green, A.J., Yeaman, M.R., Smith, T.J., Cook, L., Paul, F. and Brandt, A.U.
Journal of Neuro-Ophthalmology
29 September 2023
(In Press)
Scaling the mountains: what lies above 7 Tesla magnetic resonance?
Schmidt, R., Keban, E., Bollmann, S., Wiggins, C.J. and Niendorf, T.
Magnetic Resonance Materials in Physics Biology and Medicine 36
(2): 151-157.
April 2023
Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH.
Singh, M., Kondraskhina, A.M., Hurst, L.D. and Izsvák, Z.
Journal of Clinical Investigation 133
(14): e172278.
17 July 2023
Systematic perturbation of chromatin factors identifies regulatory networks during healthy and malignant hematopoiesis.
Solé-Boldo, L. and Haas, S.
Nature Genetics 55
(9): 1430-1431.
September 2023
Genome architecture mapping detects transcriptionally active, multiway chromatin contacts.
Thieme, C.J. and Pombo, A.
Nature Methods 20
(7): 993-994.
July 2023
The brain's encoding of warm and cool.
Vestergaard, M. and Poulet, J.
Nature
8 February 2023
(In Press)
Human gut microbiome researches over the last decade: current challenges and future directions.
Wu, H., Forslund, S., Wang, Z. and Zhao, G.
Phenomics
23 October 2023
(In Press)
Der Krebsforscher Otto Mühlbock als junger Assistent in der Frauenklinik der Charité [The cancer researcher Otto Mühlbock as a young assistant in the Charité Gynecological Clinic].
Wunderlich, V. and van Doornum, G.J.J.
Geburtshilfe und Frauenheilkunde 83
(1): 28-31.
January 2023
What do you most hope spatial molecular profiling will help us understand? Part 2.
Yanai, I., Fertig, E.J., Li, M., Coscia, F., Klughammer, J., Nie, Q., Chen, J. and Coskun, A.F.
Cell Systems 14
(7): 543-546.
19 July 2023
Comment
Turning science into cover art.
Dauben, H., Matic, I., Kidmose, R.T., Pedersen, B.P., Saha, T., Di Virgilio, M. and Sung, J.H.
Trends in Biochemical Sciences 48
(12): 1009-1011.
December 2023
Translating metabolomics into clinical practice.
Kirwan, J.A.
Nature Reviews Bioengineering 1
: 228-229.
April 2023
Preprint
Replicative aging impedes stress-induced assembly of a key human protein disaggregase.
Mathangasinghe, Y., Alberts, N., Rosado, C.J., Cox, D., Payne, N.L., Ormsby, A.R., Alp, K.M., Sakson, R., Uthishtran, S., Ruppert, T., Arumugam, S., Hatters, D.M., Kampinga, H.H. and Nillegoda, N.B.
bioRxiv
: 2022.06.25.497591.
8 January 2023
Cellular and synaptic diversity of layer 2-3 pyramidal neurons in human individuals.
Planert, H., Mittermaier, F.X., Grosser, S., Fidzinski, P., Schneider, U.C., Radbruch, H., Onken, J., Holtkamp, M., Schmitz, D., Alle, H., Vida, I., Geiger, J.R.P. and Peng, Y.
bioRxiv
: 2021.11.08.467668.
24 January 2023
RIF1 acts as a gatekeeper of B cell identity during late differentiation.
Rahjouei, A., Kabrani, E., Berruezo-Llacuna, M., Altwasser, R., Delgado-Benito, V., Pavri, R. and Di Virgilio, M.
bioRxiv
: 2023.07.18.549543v2.
20 July 2023
Cytokines as potential novel therapeutic targets in severe inflammatory cardiomyopathy.
Suwalski, P., Golpour, A., Weiner, J., Musigk, N., Balzer, F., Giesa, N., Amr, A., Trebing, J., Sedaghat, F., Meder, B., Beule, D., Landmesser, U. and Heidecker, B.
bioRxiv
: 2023.07.27.23293253.
4 August 2023
This list was generated on Sat Dec 21 17:56:47 2024 UTC.