Article
Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice.
Abolhassani, M., Guais, A., Sanders, E., Campion, F., Fichtner, I., Bonte, J., Baronzio, G., Fiorentini, G., Israel, M. and Schwartz, L.
Investigational New Drugs 30
(4): 1331-1342.
August 2012
Comparative evaluation of the biological properties of reducible and acid-sensitive folate prodrugs of a highly potent doxorubicin derivative.
Abu Ajaj, K., El-Abadla, N., Welker, P., Azab, S., Zeisig, R., Fichtner, I. and Kratz, F.
European Journal of Cancer 48
(13): 2054-2065.
September 2012
Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest.
Adameyko, I., Lallemend, F., Furlan, A., Zinin, N., Aranda, S., Kitambi, S.S., Blanchart, A., Favaro, R., Nicolis, S., Luebke, M., Mueller, T., Birchmeier, C., Suter, U., Zaitoun, I., Takahashi, Y. and Ernfors, P.
Development 139
(2): 397-410.
15 January 2012
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia.
Akalin, A., Garrett-Bakelman, F.E., Kormaksson, M., Busuttil, J., Zhang, L., Khrebtukova, I., Milne, T.A., Huang, Y., Biswas, D., Hess, J.L., Allis, C.D., Roeder, R.G., Valk, P.J.M., Loewenberg, B., Delwel, R., Fernandez, H.F., Paietta, E., Tallman, M.S., Schroth, G.P., Mason, C.E., Melnick, A. and Figueroa, M.E.
PLoS Genetics 8
(6): e1002781.
21 June 2012
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles.
Akalin, A., Kormaksson, M., Li, S., Garrett-Bakelman, F.E., Figueroa, M.E., Melnick, A. and Mason, C.E.
Genome Biology 13
(10): R87.
3 October 2012
Is simultaneous splenectomy an additive risk factor in surgical treatment for active endocarditis?
Akhyari, P., Mehrabi, A., Adhiwana, A., Kamiya, H., Nimptsch, K., Minol, J.P., Tochtermann, U., Godehardt, E., Weitz, J., Lichtenberg, A., Karck, M. and Ruhparwar, A.
Langenbeck's Archives of Surgery 397
(8): 1261-1266.
December 2012
Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation.
Albert-Weissenberger, C., Stetter, C., Meuth, S.G., Goebel, K., Bader, M., Siren, A.L. and Kleinschnitz, C.
Journal of Cerebral Blood Flow and Metabolism 32
(9): 1747-1756.
September 2012
Total and high-molecular-weight adiponectin and risk of colorectal cancer: the European Prospective Investigation into Cancer and Nutrition study.
Aleksandrova, K., Boeing, H., Jenab, M., Bueno-de-Mesquita, H.B., Jansen, E., van Duijnhoven, F.J., Fedirko, V., Rinaldi, S., Romieu, I., Riboli, E., Romaguera, D., Westphal, S., Overvad, K., Tjonneland, A., Boutron-Ruault, M.C., Clavel-Chapelon, F., Kaaks, R., Lukanova, A., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Agnoli, C., Mattiello, A., Saieva, C., Vineis, P., Tumino, R., Peeters, P.H., Argueelles, M., Bonet, C., Sanchez, M.J., Dorronsoro, M., Huerta, J.M., Barricarte, A., Palmqvist, R., Hallmans, G., Khaw, K.T., Wareham, N., Allen, N.E., Crowe, F.L. and Pischon, T.
Carcinogenesis 33
(6): 1211-1218.
November 2012
Leptin and soluble leptin receptor in risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition Cohort.
Aleksandrova, K., Boeing, H., Jenab, M., Bueno-de-Mesquita, H.B., Jansen, E., van Duijnhoven, F.J.B., Rinaldi, S., Fedirko, V., Romieu, I., Riboli, E., Gunter, M.J., Westphal, S., Overvad, K., Tjonneland, A., Halkjaer, J., Racine, A., Boutron-Ruault, M.C., Clavel-Chapelon, F., Kaaks, R., Lukanova, A., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Mattiello, A., Pala, V., Palli, D., Tumino, R., Vineis, P., Buckland, G., Sanchez, M.J., Amiano, P., Huerta, J.M., Barricarte, A., Menendez, V., Peeters, P.H., Soederberg, S., Palmqvist, R., Allen, N.E., Crowe, F.L., Khaw, K.T., Wareham, N. and Pischon, T.
Cancer Research 72
(20): 5328-5337.
15 October 2012
Impaired modulation of the cardiac L-type Ca2+ channel activity by ahnak-1 after myocardial infarction.
Alvarez Gonzalez, J., Haase, H., Vassort, G. and Morano, I.
Revista Cubana de Cardiologia y Cirugia Cardiovascular 18
(3): 142-148.
2012
Sonic hedgehog lineage in the mouse hypothalamus: from progenitor domains to hypothalamic regions.
Alvarez-Bolado, G., Paul, F.A. and Blaess, S.
Neural Development 7
: 4.
20 January 2012
Retargeting transposon insertions by the adeno-associated virus Rep protein.
Ammar, I., Gogol-Doering, A., Miskey, C., Chen, W., Cathomen, T., Izsvak, Z. and Ivics, Z.
Nucleic Acids Research 40
(14): 6693-6712.
1 August 2012
The sleeping beauty transposon toolbox.
Ammar, I., Izsvak, Z. and Ivics, Z.
Methods in Molecular Biology 859
: 229-240.
31 January 2012
TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure.
An, J., Harms, C., Lättig-Tünnemann, G., Sellge, G., Mandic, A.D., Malato, Y., Heuser, A., Endres, M., Trautwein, C. and Donath, S.
Hepatology 56
(2): 715-726.
August 2012
doRiNA: a database of RNA interactions in post-transcriptional regulation.
Anders, G., Mackowiak, S.D., Jens, M., Maaskola, J., Kuntzagk, A., Rajewsky, N., Landthaler, M. and Dieterich, C.
Nucleic Acids Research 40
(1): D180-D186.
January 2012
Depot formation of doxycycline impairs Tet-regulated gene expression in vivo.
Anders, K., Buschow, C., Charo, J. and Blankenstein, T.
Transgenic Research 21
(5): 1099-1107.
October 2012
Mining the literature: new methods to exploit keyword profiles.
Andrade-Navarro, M.A.
Genome Medicine 4
(10): 81.
30 October 2012
Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system.
Andresen, D., Roske, Y., Doering, C., Heinemann, U., Seckler, R. and Barbirz, S.
Molecular Microbiology 83
(6): 1244-1253.
March 2012
High-resolution intravital microscopy.
Andresen, V., Pollok, K., Rinnenthal, J.L., Oehme, L., Guenther, R., Spiecker, H., Radbruch, H., Gerhard, J., Sporbert, A., Cseresnyes, Z., Hauser, A.E. and Niesner, R.
PLoS ONE 7
(12): e50915.
14 December 2012
FMRP targets distinct mRNA sequence elements to regulate protein expression.
Ascano, M., Mukherjee, N., Bandaru, P., Miller, J.B., Nusbaum, J.D., Corcoran, D.L., Langlois, C., Munschauer, M., Dewell, S., Hafner, M., Williams, Z., Ohler, U. and Tuschl, T.
Nature 492
(7429): 382-386.
20 December 2012
Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish.
Asharani, P.V., Keupp, K., Semler, O., Wang, W., Li, Y., Thiele, H., Yigit, G., Pohl, E., Becker, J., Frommolt, P., Sonntag, C., Altmüller, J., Zimmermann, K., Greenspan, D.S., Akarsu, N.A., Netzer, C., Schönau, E., Wirth, R., Hammerschmidt, M., Nürnberg, P., Wollnik, B. and Carney, T.J.
American Journal of Human Genetics 90
(4): 661-74.
6 April 2012
Pioglitazone prevents capillary rarefaction in streptozotocin-diabetic rats independently of glucose control and vascular endothelial growth factor expression.
Ashoff, A., Qadri, F., Eggers, R., Joehren, O., Raasch, W. and Dendorfer, A.
Journal of Vascular Research 49
(3): 260-266.
May 2012
Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.
Ashrafian, H., Czibik, G., Bellahcene, M., Aksentijević, D., Smith, A.C., Mitchell, S.J., Dodd, M.S., Kirwan, J., Byrne, J.J., Ludwig, C., Isackson, H., Yavari, A., Støttrup, N.B., Contractor, H., Cahill, T.J., Sahgal, N., Ball, D.R., Birkler, R.I.D., Hargreaves, I., Tennant, D.A., Land, J., Lygate, C.A., Johannsen, M., Kharbanda, R.K., Neubauer, S., Redwood, C., de Cabo, R., Ahmet, I., Talan, M., Günther, U.L., Robinson, A.J., Viant, M.R., Pollard, P.J., Tyler, D.J. and Watkins, H.
Cell Metabolism 15
(3): 361-371.
7 March 2012
Determination of interaction kinetics between the T cell receptor and peptide-loaded MHC class II via single-molecule diffusion measurements.
Axmann, M., Huppa, J.B., Davis, M.M. and Schütz, G.J.
Biophysical Journal 103
(2): L17-9.
18 July 2012
The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity.
Baek, J.H., Birchmeier, C., Zenke, M. and Hieronymus, T.
Journal of Immunology 189
(4): 1699-1707.
15 August 2012
The hinge region of the scaffolding protein of cell contacts, zonula occludens protein 1, regulates interacting with various signaling proteins.
Bal, M.S., Castro, V., Piontek, J., Rueckert, C., Walter, J.K., Shymanets, A., Kurig, B., Haase, H., Nuernberg, B. and Blasig, I.E.
Journal of Cellular Biochemistry 113
(3): 934-945.
March 2012
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz, A.G., Munschauer, M., Schwanhaeusser, B., Vasile, A., Murakawa, Y., Schueler, M., Youngs, N., Penfold-Brown, D., Drew, K., Milek, M., Wyler, E., Bonneau, R., Selbach, M., Dieterich, C. and Landthaler, M.
Molecular Cell 46
(5): 674-690.
8 June 2012
Reported behavior of eating anything at anytime and risk of colorectal cancer in women.
Bao, Y., Nimptsch, K., Chan, A.T., Ng, K., Meyerhardt, J.A., Willett, W.C., Giovannucci, E. and Fuchs, C.S.
International Journal of Cancer 130
(6): 1395-1400.
15 March 2012
Complexity of chromatin folding is captured by the strings and binders switch model.
Barbieri, M., Chotalia, M., Fraser, J., Lavitas, L.M., Dostie, J., Pombo, A. and Nicodemi, M.
Proceedings of the National Academy of Sciences of the United States of America 109
(40): 16173-16178.
2 October 2012
Bicuspid aortic valve is associated with altered wall shear stress in the ascending aorta.
Barker, A.J., Markl, M., Buerk, J., Lorenz, R., Bock, J., Bauer, S., Schulz-Menger, J. and von Knobelsdorff-Brenkenhoff, F.
Circulation Cardiovascular Imaging 5
(4): 457-466.
July 2012
Altered glucose homeostasis and hepatic function in obese mice deficient for both kinin receptor genes.
Barros, C.C., Haro, A., Russo, F.J.V.P., Schadock, I., Almeida, S.S., Ribeiro, R.A., Vanzela, E.C., Lanzoni, V.P., Barros, F.C., Moraes, M.R., Mori, M.A., Bacurau, R.F.P., Wurtele, M., Boschero, A.C., Carneiro, E.M., Bader, M., Pesquero, J.B. and Araujo, R.C.
PLoS ONE 7
(7): e40573.
19 July 2012
Renoprotective effects of AVE0991, a nonpeptide Mas receptor agonist, in experimental acute renal injury.
Barroso, L.C., Silveira, K.D., Lima, C.X., Borges, V., Bader, M., Rachid, M., Souza Santos, R.A., Souza, D.G., Simoes e Silva, A.C. and Teixeira, M.M.
International Journal of Hypertension 2012
: 808726.
2012
Endothelium dependent expression and underlying mechanisms of des-Arg(9)-bradykinin-induced B(1)R-mediated vasoconstriction in rat portal vein.
Basei, F.L., Cabrini, D.A., Figueiredo, C.P., Forner, S., Hara, D.B., Nascimento, A.F.Z., Ceravolo, G.S., Carvalho, M.H.C., Bader, M., Medeiros, R. and Calixto, J.B.
Peptides 37
(2): 216-224.
October 2012
Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome.
Basel-Vanagaite, L., Dallapiccola, B., Ramirez-Solis, R., Segref, A., Thiele, H., Edwards, A., Arends, M.J., Miró, X., White, J.K., Désir, J., Abramowicz, M., Dentici, M.L., Lepri, F., Hofmann, K., Har-Zahav, A., Ryder, E., Karp, N.A., Estabel, J., Gerdin, A.K.B., Podrini, C., Ingham, N.J., Altmüller, J., Nürnberg, G., Frommolt, P., Abdelhak, S., Pasmanik-Chor, M., Konen, O., Kelley, R.I., Shohat, M., Nürnberg, P., Flint, J., Steel, K.P., Hoppe, T., Kubisch, C., Adams, D.J. and Borck, G.
American Journal of Human Genetics 91
(6): 998-1010.
7 December 2012
Mutations in FKBP14 cause a variant of Ehlers-Danlos syndrome with progressive kyphoscoliosis, myopathy, and hearing loss.
Baumann, M., Giunta, C., Krabichler, B., Rueschendorf, F., Zoppi, N., Colombi, M., Bittner, R.E., Quijano-Roy, S., Muntoni, F., Cirak, S., Schreiber, G., Zou, Y., Hu, Y., Romero, N.B., Carlier, R.Y., Amberger, A., Deutschmann, A., Straub, V., Rohrbach, M., Steinmann, B., Rostasy, K., Karall, D., Boennemann, C.G., Zschocke, J. and Fauth, C.
American Journal of Human Genetics 90
(2): 201-216.
10 February 2012
Axonal transcription factors signal retrogradely in lesioned peripheral nerve.
Ben-Yaakov, K., Dagan, S.Y., Segal-Ruder, Y., Shalem, O., Vuppalanchi, D., Willis, D.E., Yudin, D., Rishal, I., Rother, F., Bader, M., Blesch, A., Pilpel, Y., Twiss, J.L. and Fainzilber, M.
EMBO Journal 31
(6): 1350-1363.
13 January 2012
Sexual dimorphic regulation of body weight dynamics and adipose tissue lipolysis.
Benz, V., Bloch, M., Wardat, S., Boehm, C., Maurer, L., Mahmoodzadeh, S., Wiedmer, P., Spranger, J., Foryst-Ludwig, A. and Kintscher, U.
PLoS ONE 7
(5): e37794.
25 May 2012
Apoptotic cleavage of DNA in human lymphocyte chromatin shows high sequence specificity.
Bettecken, T., Frenkel, Z.M., Altmüller, J., Nürnberg, P. and Trifonov, E.N.
Journal of Biomolecular Structure & Dynamics 30
(2): 211-6.
12 June 2012
Replicative aging and differentiation potential of human adipose tissue-derived mesenchymal stromal cells expanded in pooled human or fetal bovine serum.
Bieback, K., Hecker, A., Schlechter, T., Hofmann, I., Brousos, N., Redmer, T., Besser, D., Klueter, H., Mueller, A.M. and Becker, M.
Cytotherapy 14
(5): 570-583.
May 2012
Early type II fiber atrophy in intensive care unit patients with nonexcitable muscle membrane.
Bierbrauer, J., Koch, S., Olbricht, C., Hamati, J., Lodka, D., Schneider, J., Luther-Schroeder, A., Kleber, C., Faust, K., Wiesener, S., Spies, C.D., Spranger, J., Spuler, S., Fielitz, J. and Weber-Carstens, S.
Critical Care Medicine 40
(2): 647-650.
February 2012
Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.
Bieschke, J., Herbst, M., Wiglenda, T., Friedrich, R.P., Boeddrich, A., Schiele, F., Kleckers, D., Lopez Del Amo, J.M., Gruening, B.A., Wang, Q., Schmidt, M.R., Lurz, R., Anwyl, R., Schnoegl, S., Faendrich, M., Frank, R.F., Reif, B., Guenther, S., Walsh, D.M. and Wanker, E.E.
Nature Chemical Biology 8
(1): 93-101.
January 2012
Decreased hepatic gluconeogenesis in transgenic rats with increased circulating angiotensin-(1-7).
Bilman, V., Mares-Guia, L., Nadu, A.P., Bader, M., Campagnole-Santos, M.J., Santos, R.A.S. and Santos, S.H.S.
Peptides 37
(2): 247-251.
October 2012
Atrial natriuretic Peptide and adiponectin interactions in man.
Birkenfeld, A.L., Boschmann, M., Engeli, S., Moro, C., Arafat, A.M., Luft, F.C. and Jordan, J.
PLoS ONE 7
(8): e43238.
16 August 2012
The role of Irf6 in tooth epithelial invagination.
Blackburn, J., Ohazama, A., Kawasaki, K., Otsuka-Tanaka, Y., Liu, B., Honda, K., Rountree, R.B., Hu, Y., Kawasaki, M., Birchmeier, W., Schmidt-Ullrich, R., Kinoshita, A., Schutte, B.C., Hammond, N.L., Dixon, M.J. and Sharpe, P.T.
Developmental Biology 365
(1): 61-70.
1 May 2012
Spontaneous and therapy-induced T cell responses to cancer.
Blankenstein, T.
Arzneimittelforschung 62
(1): S9.
November 2012
The determinants of tumour immunogenicity.
Blankenstein, T., Coulie, P.G., Gilboa, E. and Jaffee, E.M.
Nature Reviews Cancer 12
(4): 307-313.
April 2012
Absent proximal right coronary artery with a fistula into the pulmonary vein.
Blaschke, F., Baur, A., Roser, M., Attanasio, P., Ozcelik, C., Haverkamp, W. and Boldt, L.H.
Europace 14
(9): 1369-1370.
September 2012
Ventricular tachycardia or ventricular fibrillation occurs less often in patients with left bundle branch block and combined resynchronization and defibrillators than in patients with narrow QRS and conventional defibrillators.
Blaschke, F., Knaus, T., Celebi, O., Krebs, A., Nitardy, A., Habedank, D., Dietz, R. and Stockburger, M.
Europace 14
(2): 224-229.
February 2012
Impairment of contrast visual acuity as a functional correlate of retinal nerve fibre layer thinning and total macular volume reduction in multiple sclerosis.
Bock, M., Brandt, A.U., Kuchenbecker, J., Doerr, J., Pfueller, C.F., Weinges-Evers, N., Gaede, G., Zimmermann, H., Bellmann-Strobl, J., Ohlraun, S., Zipp, F. and Paul, F.
British Journal of Ophthalmology 96
(1): 62-67.
January 2012
Blood pressure and renin-angiotensin system resetting in transgenic rats with elevated plasma Val5-angiotensinogen.
Bohlender, J., Bader, M., Menard, J. and Nussberger, J.
Journal of Hypertension 30
(8): 1597-1605.
August 2012
Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development.
Bonn, S., Zinzen, R.P., Girardot, C., Gustafson, E.H., Perez-Gonzalez, A., Delhomme, N., Ghavi-Helm, Y., Wilczynski, B., Riddell, A. and Furlong, E.E.
Nature Genetics 44
(2): 148-156.
February 2012
Cell type-specific chromatin immunoprecipitation from multicellular complex samples using BiTS-ChIP.
Bonn, S., Zinzen, R.P., Perez-Gonzalez, A., Riddell, A., Gavin, A.C. and Furlong, E.E.
Nature Protocols 7
(5): 978-994.
May 2012
eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation.
Borck, G., Shin, B.S., Stiller, B., Mimouni-Bloch, A., Thiele, H., Kim, J.R., Thakur, M., Skinner, C., Aschenbach, L., Smirin-Yosef, P., Har-Zahav, A., Nürnberg, G., Altmüller, J., Frommolt, P., Hofmann, K., Konen, O., Nürnberg, P., Munnich, A., Schwartz, C.E., Gothelf, D., Colleaux, L., Dever, T.E., Kubisch, C. and Basel-Vanagaite, L.
Molecular Cell 48
(4): 641-6.
30 November 2012
Aliskiren penetrates adipose and skeletal muscle tissue and reduces renin-angiotensin system activity in obese hypertensive patients.
Boschmann, M., Nussberger, J., Engeli, S., Danser, A.H.J., Yeh, C.M., Prescott, M.F., Dahlke, M. and Jordan, J.
Journal of Hypertension 30
(3): 561-566.
March 2012
Altered regional blood flow distribution in Mas-deficient mice.
Botelho-Santos, G.A., Bader, M., Alenina, N. and Santos, R.A.
Therapeutic Advances in Cardiovascular Disease 6
(5): 201-211.
October 2012
A stomatin dimer modulates the activity of acid-sensing ion channels.
Brand, J., Smith, E.S.J., Schwefel, D., Lapatsina, L., Poole, K., Omerbasic, D., Kozlenkov, A., Behlke, J., Lewin, G.R. and Daumke, O.
EMBO Journal 31
(17): 3635-3646.
29 August 2012
Patterns of retinal damage facilitate differential diagnosis between susac syndrome and MS.
Brandt, A.U., Zimmermann, H., Kaufhold, F., Promesberger, J., Schippling, S., Finis, D., Aktas, O., Geis, C., Ringelstein, M., Ringelstein, E.B., Hartung, H.P., Paul, F., Kleffner, I. and Doerr, J.
PLoS ONE 7
(6): e38741.
11 June 2012
High-resolution experimental and computational profiling of tissue-specific known and novel miRNAs in Arabidopsis.
Breakfield, N.W., Corcoran, D.L., Petricka, J.J., Shen, J., Sae-Seaw, J., Rubio-Somoza, I., Weigel, D., Ohler, U. and Benfey, P.N.
Genome Research 22
(1): 163-176.
January 2012
Deletion of claudin-10 (Cldn10) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis.
Breiderhoff, T., Himmerkus, N., Stuiver, M., Mutig, K., Will, C., Meij, I.C., Bachmann, S., Bleich, M., Willnow, T.E. and Mueller, D.
Proceedings of the National Academy of Sciences of the United States of America 109
(35): 14241-14246.
28 August 2012
Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates.
Briesemeister, D., Friese, C., Isern, C.C., Dietz, E., Blankenstein, T., Thoene-Reineke, C. and Kammertoens, T.
Cytokine 60
(3): 626-633.
December 2012
Anti-β-adrenoceptors autoimmunity causing 'idiopathic' arrhythmias and cardiomyopathy.
Brisinda, D., Sorbo, A.R., Venuti, A., Ruggieri, M.P., Manna, R., Fenici, P., Wallukat, G., Hoebeke, J., Frustaci, A. and Fenici, R.
Circulation Journal 76
(6): 1345-1353.
25 May 2012
Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on notch signals.
Broehl, D., Vasyutina, E., Czajkowski, M.T., Griger, J., Rassek, C., Rahn, H.P., Purfürst, B., Wende, H. and Birchmeier, C.
Developmental Cell 23
(3): 469-481.
11 September 2012
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs.
Brookes, E., de Santiago, I., Hebenstreit, D., Morris, K.J., Carroll, T., Xie, S.Q., Stock, J.K., Heidemann, M., Eick, D., Nozaki, N., Kimura, H., Ragoussis, J., Teichmann, S.A. and Pombo, A.
Cell Stem Cell 10
(2): 157-170.
3 February 2012
A microfluidic device and computational platform for high-throughput live imaging of gene expression.
Busch, W., Moore, B.T., Martsberger, B., Mace, D.L., Twigg, R.W., Jung, J., Pruteanu-Malinici, I., Kennedy, S.J., Fricke, G.K., Clark, R.L., Ohler, U. and Benfey, P.N.
Nature Methods 9
(11): 1101-1106.
November 2012
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Bywater, M.J., Poortinga, G., Sanij, E., Hein, N., Peck, A., Cullinane, C., Wall, M., Cluse, L., Drygin, D., Anderes, K., Huser, N., Proffitt, C., Bliesath, J., Haddach, M., Schwaebe, M.K., Ryckman, D.M., Rice, W.G., Schmitt, C., Lowe, S.W., Johnstone, R.W., Pearson, R.B., McArthur, G.A. and Hannan, R.D.
Cancer Cell 22
(1): 51-65.
10 July 2012
Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3.
Cadot, B., Gache, V., Vasyutina, E., Falcone, S., Birchmeier, C. and Gomes, E.R.
EMBO Reports 13
(8): 741-749.
1 August 2012
Identification of Alzheimer disease risk genotype that predicts efficiency of SORL1 expression in the brain.
Caglayan, S., Bauerfeind, A., Schmidt, V., Carlo, A.S., Prabakaran, T., Huebner, N. and Willnow, T.E.
Archives of Neurology 69
(3): 373-379.
March 2012
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers.
Calado, D.P., Sasaki, Y., Godinho, S.A., Pellerin, A., Köchert, K., Sleckman, B.P., de Alboran, I.M., Janz, M., Rodig, S. and Rajewsky, K.
Nature Immunology 13
(11): 1092-1100.
November 2012
TrakEM2 software for neural circuit reconstruction.
Cardona, A., Saalfeld, S., Schindelin, J., Arganda-Carreras, I., Preibisch, S., Longair, M., Tomancak, P., Hartenstein, V. and Douglas, R.J.
PLoS ONE 7
(6): e38011.
19 June 2012
PI3kγ inhibition reduces blood pressure by a vasorelaxant Akt/LTCC mechanism.
Carnevale, D., Vecchione, C., Mascio, G., Esposito, G., Cifelli, G., Martinello, K., Landolfi, A., Selvetella, G., Grieco, P., Damato, A., Franco, E., Haase, H., Maffei, A., Ciraolo, E., Fucile, S., Frati, G., Mazzoni, O., Hirsch, E. and Lembo, G.
Cardiovascular Research 93
(1): 200-209.
1 January 2012
Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin.
Casas-Delucchi, C.S., van Bemmel, J.G., Haase, S., Herce, H.D., Nowak, D., Meilinger, D., Stear, J.H., Leonhardt, H. and Cardoso, M.C.
Nucleic Acids Research 40
(1): 159-169.
1 January 2012
Dynamo: a flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments.
Castaño-Díez, D., Kudryashev, M., Arheit, M. and Stahlberg, H.
Journal of Structural Biology 178
(2): 139-151.
May 2012
Bradykinin inhibits hepatic gluconeogenesis in obese mice.
Castilho Barros, C., Haro, A., Russo, F.J., Schadock, I., Soares Almeida, S., Castellani Reis, F., Rocha Moraes, M., Haidar, A., Hirata, A.E., Mori, M.A., Pereira Bacurau, R.F., Wuertele, M., Bader, M., Bosco Pesquero, J. and Araujo, R.C.
Laboratory Investigation 92
(10): 1419-1427.
October 2012
Impaired nociception and peripheral opioid antinociception in mice lacking both kinin b1 and b2 receptors.
Cayla, C., Labuz, D., Machelska, H., Bader, M., Schaefer, M. and Stein, C.
Anesthesiology 116
(2): 448-457.
February 2012
Extraordinarily favorable left ventricular reverse remodeling through long-term cardiac resynchronization: super-response to cardiac resynchronization.
Celebi, O., Knaus, T., Blaschke, F., Habedank, D., Doehner, W., Nitardy, A. and Stockburger, M.
Pacing and Clinical Electrophysiology 35
(7): 870-876.
July 2012
Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.
Cerrone, M., Noorman, M., Lin, X., Chkourko, H., Liang, F.X., van der Nagel, R., Hund, T., Birchmeier, W., Mohler, P., van Veen, T.A., van Rijen, H.V. and Delmar, M.
Cardiovascular Research 95
(4): 460-468.
1 September 2012
Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.
Cesca, F., Yabe, A., Spencer-Dene, B., Scholz-Starke, J., Medrihan, L., Maden, C.H., Gerhardt, H., Orriss, I.R., Baldelli, P., Al-Qatari, M., Koltzenburg, M., Adams, R.H., Benfenati, F. and Schiavo, G.
Cell Death and Differentiation 19
(2): 194-208.
February 2012
Combined RNAi and localization for functionally dissecting long noncoding RNAs.
Chakraborty, D., Kappei, D., Theis, M., Nitzsche, A., Ding, L., Paszkowski-Rogacz, M., Surendranath, V., Berger, N., Schulz, H., Saar, K., Hubner, N. and Buchholz, F.
Nature Methods 9
(4): 360-362.
12 February 2012
Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation.
Chan, M.V., Bubb, K.J., Noyce, A., Villar, I.C., Duchene, J., Hobbs, A.J., Scotland, R.S. and Ahluwalia, A.
British Journal of Pharmacology 167
(4): 805-817.
October 2012
Mitoxantrone induces natural killer cell maturation in patients with secondary progressive multiple sclerosis.
Chanvillard, C., Millward, J.M., Lozano, M., Hamann, I., Paul, F., Zipp, F., Doerr, J. and Infante-Duarte, C.
PLoS ONE 7
(6): e39625.
29 June 2012
OGEE: an online gene essentiality database.
Chen, W.H., Minguez, P., Lercher, M.J. and Bork, P.
Nucleic Acids Research 40
(Database issue): D901-D906.
January 2012
Purpura und Nierenversagen bei einer Patientin mit colitis ulcerosa [Purpura and renal failure in a patient with ulcerative colitis].
Choi, M., Schneider, W. and Kettritz, R.
Nephrologe 7
(3): 238-242.
May 2012
LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals.
Christ, A., Christa, A., Kur, E., Lioubinski, O., Bachmann, S., Willnow, T.E. and Hammes, A.
Developmental Cell 22
(2): 268-278.
14 February 2012
Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter.
Chua, J.J.E., Butkevich, E., Worseck, J.M., Kittelmann, M., Gronborg, M., Behrmann, E., Stelzl, U., Pavlos, N.J., Lalowski, M.M., Eimer, S., Wanker, E.E., Klopfenstein, D.R. and Jahn, R.
Proceedings of the National Academy of Sciences of the United States of America 109
(15): 5862-5867.
10 April 2012
In vivo conditions to identify prkci phosphorylation targets using the analog-sensitive kinase method in zebrafish.
Cibrian Uhalte, E., Kirchner, M., Hellwig, N., Allen, J.J., Donat, S., Shokat, K.M., Selbach, M. and Abdelilah-Seyfried, S.
PLoS ONE 7
(6): e40000.
29 June 2012
A validated regulatory network for Th17 cell specification.
Ciofani, M., Madar, A., Galan, C., Sellars, M., Mace, K., Pauli, F., Agarwal, A., Huang, W., Parkurst, C.N., Muratet, M., Newberry, K.M., Meadows, S., Greenfield, A., Yang, Y., Jain, P., Kirigin, F.K., Birchmeier, C., Wagner, E.F., Murphy, K.M., Myers, R.M., Bonneau, R. and Littman, D.R.
Cell 151
(2): 289-303.
12 October 2012
Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP.
Courtial, N., Smink, J.J., Kuvardina, O.N., Leutz, A., Goethert, J.R. and Lausen, J.
FASEB Journal 26
(2): 523-532.
February 2012
Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.
Dahlmann, M., Sack, U., Herrmann, P., Lemm, M., Fichtner, I., Schlag, P.M. and Stein, U.
Oncotarget 3
(8): 783-797.
7 August 2012
Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis.
Dal Santo, S., Stampfl, H., Krasensky, J., Kempa, S., Gibon, Y., Petutschnig, E., Rozhon, W., Heuck, A., Clausen, T. and Jonak, C.
Plant Cell 24
(8): 3380-3392.
August 2012
Long-term benefits of immunoadsorption in beta(1)-adrenoceptor autoantibody-positive transplant candidates with dilated cardiomyopathy.
Dandel, M., Wallukat, G., Englert, A., Lehmkuhl, H.B., Knosalla, C. and Hetzer, R.
European Journal of Heart Failure 14
(12): 1374-1388.
December 2012
Hypertonie und Depression : Zusammenhaenge und Probleme des gemeinsamen Auftretens [Hypertension and depression : context and issues of joint appearances].
Dechend, R.
Diabetes, Stoffwechsel und Herz 21
(5): 334-335.
October 2012
Activating autoantibodies against the AT1-receptor in vascular disease.
Dechend, R., Dragun, D., Herse, F., Riemekasten, G., Schulze-Forster, K., Mueller, D.N. and Heidecke, H.
Transplantationsmedizin 24
(1): 20-26.
2012
Guideline adherence in cardiovascular risk assessment and analysis in 15,000 hypertensive German patients in real life: results of the Prospective 3A Registry.
Dechend, R., Kaiser, E., Derer, W., Deeg, E., Busjahn, A., Schmieder, R.E. and Zeymer, U.
Journal of Clinical Hypertension 14
(8): 496-501.
August 2012
IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy.
Dhillion, P., Wallace, K., Herse, F., Scott, J., Wallukat, G., Heath, J., Mosely, J., Martin, J.N., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 303
(4): R353-R358.
15 August 2012
N-desalkylquetiapine activates ERK1/2 to induce GDNF release in C6 glioma cells: a putative cellular mechanism for quetiapine as antidepressant.
Di Benedetto, B., Kuehn, R., Nothdurfter, C., Rein, T., Wurst, W. and Rupprecht, R.
Neuropharmacology 62
(1): 209-216.
January 2012
Design, construction, and evaluation of a dynamic MR compatible cardiac left ventricle model.
Dieringer, M.A., Hentschel, J., de Quadros, T., von Knobelsdorff-Brenkenhoff, F., Hoffmann, W., Niendorf, T. and Schulz-Menger, J.
Medical Physics 39
(8): 4800-4806.
August 2012
Genome-wide search for miRNA-target interactions in Arabidopsis thaliana with an integrated approach.
Ding, J., Li, D., Ohler, U., Guan, J. and Zhou, S.
BMC Genomics 13
(Suppl 3): S3.
11 June 2012
The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma.
Dizier, M.H., Margaritte-Jeannin, P., Madore, A.M., Esparza-Gordillo, J., Moffatt, M.F., Corda, E., Monier, F., Guilloud-Bataille, M., Franke, A., Weidinger, S., Annesi-Maesano, I., Just, J., Pin, I., Kauffmann, F., Cookson, W., Lee, Y.A., Laprise, C., Lathrop, M., Bouzigon, E. and Demenais, F.
Journal of Allergy and Clinical Immunology 129
(6): 1547-1553.
June 2012
FLEXBAR: flexible barcode and adapter processing for next-generation sequencing platforms.
Dodt, M., Roehr, J.T., Ahmed, R. and Dieterich, C.
Biology 1
(3): 895-905.
14 December 2012
Annotation of the M. tuberculosis hypothetical orfeome: adding functional information to more than half of the uncharacterized proteins.
Doerks, T., van Noort, V., Minguez, P. and Bork, P.
PLoS ONE 7
(4): e34302.
2 April 2012
Efficacy of vitamin D supplementation in multiple sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trial.
Doerr, J., Ohlraun, S., Skarabis, H. and Paul, F.
Trials 13
: 15.
8 February 2012
Specific gene signatures and pathways in mesodermal cells and their derivatives derived from embryonic stem cells.
Doss, M.X., Gaspar, J.A., Winkler, J., Hescheler, J., Schulz, H. and Sachinidis, A.
Stem Cell Reviews and Reports 8
(1): 43-54.
March 2012
Integrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells.
Dudziec, E., Gogol-Doering, A., Cookson, V., Chen, W. and Catto, J.
PLoS ONE 7
(3): e32750.
7 March 2012
Granulocyte colony-stimulating factor improves cerebrovascular reserve capacity by enhancing collateral growth in the circle of Willis.
Duelsner, A., Gatzke, N., Glaser, J., Hillmeister, P., Li, M., Lee, E.J., Lehmann, K., Urban, D., Meyborg, H., Stawowy, P., Busjahn, A., Nagorka, S., Persson, A.B. and Buschmann, I.R.
Cerebrovascular Diseases 33
(5): 419-429.
May 2012
Segregation of axonal and somatic activity during fast network oscillations.
Dugladze, T., Schmitz, D., Whittington, M.A., Vida, I. and Gloveli, T.
Science 336
(6087): 1458-1461.
15 June 2012
Automatic detection and classification of teeth in CT data.
Duy, N.T., Lamecker, H., Kainmueller, D. and Zachow, S.
Lecture Notes in Computer Science 7510
: 609-616.
2012
Effects of selenium status, dietary glucosinolate intake and serum glutathione S-transferase α activity on the risk of benign prostatic hyperplasia.
Eichholzer, M., Steinbrecher, A., Kaaks, R., Teucher, B., Linseisen, J. and Rohrmann, S.
BJU International 110
(11): E879-E885.
December 2012
Vibration-synchronized magnetic resonance imaging for the detection of myocardial elasticity changes.
Elgeti, T., Tzschaetzsch, H., Hirsch, S., Krefting, D., Klatt, D., Niendorf, T., Braun, J. and Sack, I.
Magnetic Resonance in Medicine 67
(4): 919-924.
April 2012
Chronic hypokalaemia in a hypertensive patient.
Elitok, S. and Luft, F.C.
Clinical Kidney Journal 5
(3): 223-224.
June 2012
Modeling morphodynamic phenotypes and dynamic regimes of cell motion.
Enculescu, M. and Falcke, M.
Advances in Experimental Medicine and Biology 736
(3): 337-358.
2012
Circulating anandamide and blood pressure in patients with obstructive sleep apnea.
Engeli, S., Blueher, M., Jumpertz, R., Wiesner, T., Wirtz, H., Bosse-Henck, A., Stumvoll, M., Batkai, S., Pacher, P., Harvey-White, J., Kunos, G. and Jordan, J.
Journal of Hypertension 30
(12): 2345-2351.
December 2012
Influence of dietary fat ingestion on asymmetrical dimethylarginine in lean and obese human subjects.
Engeli, S., Tsikas, D., Lehmann, A.C., Boehnke, J., Haas, V., Strauss, A., Janke, J., Gorzelniak, K., Luft, F.C. and Jordan, J.
Nutrition, Metabolism, and Cardiovascular Diseases 22
(9): 720-726.
September 2012
Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial.
Engert, A., Haverkamp, H., Kobe, C., Markova, J., Renner, C., Ho, A., Zijlstra, J., Kral, Z., Fuchs, M., Hallek, M., Kanz, L., Doehner, H., Doerken, B., Engel, N., Topp, M., Klutmann, S., Amthauer, H., Bockisch, A., Kluge, R., Kratochwil, C., Schober, O., Greil, R., Andreesen, R., Kneba, M., Pfreundschuh, M., Stein, H., Eich, H.T., Mueller, R.P., Dietlein, M., Borchmann, P. and Diehl, V.
Lancet 379
(9828): 1791-1799.
12 May 2012
Regulation of adipocyte 11beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) by CCAAT/enhancer-binding protein (C/EBP) beta isoforms, LIP and LAP.
Esteves, C.L., Kelly, V., Bégay, V., Man, T.Y., Morton, N.M., Leutz, A., Seckl, J.R. and Chapman, K.E.
PLoS ONE 7
(5): e37953.
25 May 2012
DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution.
Falconer, E., Hills, M., Naumann, U., Poon, S.S.S., Chavez, E.A., Sanders, A.D., Zhao, Y., Hirst, M. and Lansdorp, P.M.
Nature Methods 9
(11): 1107-1112.
November 2012
G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1.
Ferdaoussi, M., Bergeron, V., Zarrouki, B., Kolic, J., Cantley, J., Fielitz, J., Olson, E.N., Prentki, M., Biden, T., Macdonald, P.E. and Poitout, V.
Diabetologia 55
(10): 2682-2692.
October 2012
In vitro and in vivo investigations into the carbene silver acetate anticancer drug candidate SBC1.
Fichtner, I., Cinatl, J., Michaelis, M., Sanders, L.C., Hilger, R., Kennedy, B.N., Reynolds, A.L., Hackenberg, F., Lally, G., Quinn, S.J., McRae, I. and Tacke, M.
Letters in Drug Design & Discovery 9
(9): 815-822.
November 2012
Regulation of karyopherin alpha1 and nuclear import by mammalian target of rapamycin.
Fielhaber, J.A., Tan, J., Joung, K.B., Attias, O., Huegel, S., Bader, M., Roux, P.P. and Kristof, A.S.
Journal of Biological Chemistry 287
(18): 14325-14335.
27 April 2012
Caloric restriction ameliorates angiotensin II-induced mitochondrial remodeling and cardiac hypertrophy.
Finckenberg, P., Eriksson, O., Baumann, M., Merasto, S., Lalowski, M.M., Levijoki, J., Haasio, K., Kytoe, V., Mueller, D.N., Luft, F.C., Oresic, M. and Mervaala, E.
Hypertension 59
(1): 76-84.
2012
Dynamics of saccade parameters in multiple sclerosis patients with fatigue.
Finke, C., Pech, L.M., Soemmer, C., Schlichting, J., Stricker, S., Endres, M., Ostendorf, F., Ploner, C.J., Brandt, A.U. and Paul, F.
Journal of Neurology 259
(12): 2656-2663.
December 2012
The ubiquitin-proteasome system of Saccharomyces cerevisiae.
Finley, D., Ulrich, H.D., Sommer, T. and Kaiser, P.
Genetics 192
(2): 319-360.
1 October 2012
Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.
Fjorback, A.W., Seaman, M., Gustafsen, C., Mehmedbasic, A., Gokool, S., Wu, C., Militz, D., Schmidt, V., Madsen, P., Nyengaard, J.R., Willnow, T.E., Christensen, E.I., Mobley, W.B., Nykjaer, A. and Andersen, O.M.
Journal of Neuroscience 32
(4): 1467-1480.
25 January 2012
BACE1 dependent neuregulin processing: review.
Fleck, D., Garratt, A.N., Haass, C. and Willem, M.
Current Alzheimer Research 9
(2): 178-183.
February 2012
Coffee consumption and risk of chronic disease in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany study.
Floegel, A., Pischon, T., Bergmann, M.M., Teucher, B., Kaaks, R. and Boeing, H.
American Journal of Clinical Nutrition 95
(4): 901-908.
April 2012
Sorafenib, but not sunitinib, induces regulatory T cells in the peripheral blood of patients with metastatic renal cell carcinoma.
Floercken, A., Takvorian, A., Van Lessen, A., Singh, A., Hopfenmueller, W., Doerken, B., Pezzutto, A. and Westermann, J.
Anti-Cancer Drugs 23
(3): 298-302.
March 2012
Venoarterielle ECMO als "bridge to recovery": Kardiogener Schock und Verdacht auf Myokarditis bei einer 37-Jährigen [Veno-arterial ECMO as bridge to recovery. Cardiogenic shock and suspected myocarditis in a 37-year-old patient].
Fox, H., Seeger, F.H., Schmitt, J., Potente, M., Dzemali, O., Fichtlscherer, S. and Ehrlich, J.R.
Medizinische Klinik, Intensivmedizin und Notfallmedizin 107
(3): 206-212.
April 2012
Visualization of endothelial actin cytoskeleton in the mouse retina.
Fraccaroli, A., Franco, C.A., Rognoni, E., Neto, F., Rehberg, M., Aszodi, A., Wedlich-Söldner, R., Pohl, U., Gerhardt, H. and Montanez, E.
PLoS ONE 7
(10): e47488.
24 October 2012
Detailing the use of magnetohydrodynamic effects for synchronization of MRI with the cardiac cycle: A feasibility study.
Frauenrath, T., Fuchs, K., Dieringer, M.A., Oezerdem, C., Patel, N., Renz, W., Greiser, A., Elgeti, T. and Niendorf, T.
Journal of Magnetic Resonance Imaging 36
(2): 364-372.
August 2012
A genetic basis for mechanosensory traits in humans.
Frenzel, H., Bohlender, J., Pinsker, K., Wohlleben, B., Tank, J., Lechner, S.G., Schiska, D., Jaijo, T., Rueschendorf, F., Saar, K., Jordan, J., Millan, J.M., Gross, M. and Lewin, G.R.
PLoS Biology 10
(5): e1001318.
1 May 2012
New insights into the biology of molecular subtypes of diffuse large B-cell lymphoma and Burkitt lymphoma.
Frick, M., Doerken, B. and Lenz, G.
Best Practice and Research Clinical Haematology 25
(1): 3-12.
March 2012
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades.
Friedlaender, M.R., Mackowiak, S.D., Li, N., Chen, W. and Rajewsky, N.
Nucleic Acids Research 40
(1): 37-52.
1 January 2012
Assessing the enrichment performance in targeted resequencing experiments.
Frommolt, P., Abdallah, A.T., Altmüller, J., Motameny, S., Thiele, H., Becker, C., Stemshorn, K., Fischer, M., Freilinger, T. and Nürnberg, P.
Human Mutation 33
(4): 635-41.
April 2012
Natural course of untreated microalbuminuria in children and adolescents with type 1 diabetes and the importance of diabetes duration and immigrant status: longitudinal analysis from the prospective nationwide German and Austrian diabetes survey DPV.
Galler, A., Haberland, H., Naeke, A., Hofer, S., Holder, M., Raile, K. and Holl, R.W.
European Journal of Endocrinology 166
(3): 493-501.
March 2012
Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer.
Galling, N., Kobelt, D., Aumann, J., Schmidt, M., Wittig, B., Schlag, P.M. and Walther, W.
Human Gene Therapy Part B Methods 23
(4): 264-270.
August 2012
Use of statins in lower extremity artery disease: a review.
Gargiulo, G., Giugliano, G., Brevetti, L., Sannino, A., Schiattarella, G.G., Serino, F., Carbone, A., Scudiero, F., Ferrone, M., Corrado, R., Izzo, R., Chiariotti, L., Perrino, C., Amato, B., Trimarco, B. and Esposito, G.
BMC Surgery 12
(Suppl 1): S15.
15 November 2012
Gene expression signatures defining fundamental biological processes in pluripotent, early, and late differentiated embryonic stem cells.
Gaspar, J.A., Doss, M.X., Winkler, J., Wagh, V., Hescheler, J., Kolde, R., Vilo, J., Schulz, H. and Sachinidis, A.
Stem Cells and Development 21
(13): 2471-2484.
1 September 2012
Angiotensin-(1-7) receptor Mas is an essential modulator of extracellular matrix protein expression in the heart.
Gava, E., de Castro, C.H., Ferreira, A.J., Colleta, H., Melo, M.B., Alenina, N., Bader, M., Oliveira, L.A., Santos, R.A.S. and Kitten, G.T.
Regulatory Peptides 175
(1-3): 30-42.
10 April 2012
A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells.
Gavvovidis, I., Rost, I., Trimborn, M., Kaiser, F.J., Purps, J., Wiek, C., Hanenberg, H., Neitzel, H. and Schindler, D.
PLoS ONE 7
(8): e40387.
30 August 2012
Is target dose the treatment target? Uptitrating beta-blockers for heart failure in the elderly.
Gelbrich, G., Edelmann, F., Inkrot, S., Lainscak, M., Apostolovic, S., Neskovic, A.N., Waagstein, F., Loeffler, M., Anker, S.D., Dietz, R. and Duengen, H.D.
International Journal of Cardiology 155
(1): 160-166.
23 February 2012
Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.
Gerbitz, A., Sukumar, M., Helm, F., Wilke, A., Friese, C., Fahrenwaldt, C., Lehmann, F.M., Loddenkemper, C., Kammertoens, T., Mautner, J., Schmitt, C.A., Blankenstein, T. and Bornkamm, G.W.
PLoS ONE 7
(3): e34552.
30 March 2012
Essential role of interleukin-6 in post-stroke angiogenesis.
Gertz, K., Kronenberg, G., Kaelin, R.E., Baldinger, T., Werner, C., Balkaya, M., Eom, G.D., Hellmann-Regen, J., Kroeber, J., Miller, K.R., Lindauer, U., Laufs, U., Dirnagl, U., Heppner, F.L. and Endres, M.
Brain 135
(Pt 6): 1964-1980.
June 2012
Membrane waves driven by forces from actin filaments.
Gholami, A., Enculescu, M. and Falcke, M.
New Journal of Physics 14
: 115002.
2 November 2012
Abdominal aortic aneurysm in patients affected by intermittent claudication: prevalence and clinical predictors.
Giugliano, G., Laurenzano, E., Rengo, C., De Rosa, G., Brevetti, L., Sannino, A., Perrino, C., Chiariotti, L., Schiattarella, G.G., Serino, F., Ferrone, M., Scudiero, F., Carbone, A., Sorropago, A., Amato, B., Trimarco, B. and Esposito, G.
BMC Surgery 12
(Suppl 1): S17.
15 November 2012
Endovascular treatment of lower extremity arteries is associated with an improved outcome in diabetic patients affected by intermittent claudication.
Giugliano, G., Perrino, C., Schiano, V., Brevetti, L., Sannino, A., Schiattarella, G.G., Gargiulo, G., Serino, F., Ferrone, M., Scudiero, F., Carbone, A., Bruno, A., Amato, B., Trimarco, B. and Esposito, G.
BMC Surgery 12
(Suppl 1): S19.
15 November 2012
Ankle/brachial index to everyone.
Giugliano, G., Sannino, A., Brevetti, L., Perrino, C., Schiattarella, G.G., Franzone, A., Serino, F., Ferrone, M., Scudiero, F., Carbone, A., De Paulis, M., Izzo, R., Amato, B., Trimarco, B. and Esposito, G.
BMC Surgery 12
(Suppl 1): S18.
15 November 2012
Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb.
Glasl, L., Kloos, K., Giesert, F., Roethig, A., Di Benedetto, B., Kühn, R., Zhang, J., Hafen, U., Zerle, J., Hofmann, A., de Angelis, M.H., Winklhofer, K.F., Hölter, S.M., Vogt Weisenhorn, D.M. and Wurst, W.
Experimental Neurology 235
(1): 214-227.
May 2012
An overview of the analysis of next generation sequencing data.
Gogol-Doering, A. and Chen, W.
Methods in Molecular Biology 802
: 249-257.
2012
Cardiovascular responses evoked by activation or blockade of GABA(A) receptors in the hypothalamic PVN are attenuated in transgenic rats with low brain angiotensinogen.
Gomes da Silva, A.Q., Xavier, C.H., Campagnole-Santos, M.J., Caligiorne, S.M., Baltatu, O.C., Bader, M., Santos, R.A. and Fontes, M.A.
Brain Research 1448
: 101-110.
11 April 2012
From a concept to a word in a syntactically complete sentence: an fMRI study on spontaneous language production in an overt picture description task.
Grande, M., Meffert, E., Schoenberger, E., Jung, S., Frauenrath, T., Huber, W., Hussmann, K., Moormann, M. and Heim, S.
NeuroImage 61
(3): 702-714.
2 July 2012
MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells.
Gregersen, L.H., Jacobsen, A., Frankel, L.B., Wen, J., Krogh, A. and Lund, A.H.
BMC Cancer 12
: 232.
12 June 2012
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
Greulich, H., Kaplan, B., Mertins, P., Chen, T.H., Tanaka, K.E., Yun, C.H., Zhang, X., Lee, S.H., Cho, J., Ambrogio, L., Liao, R., Imielinski, M., Banerji, S., Berger, A.H., Lawrence, M.S., Zhang, J., Pho, N.H., Walker, S.R., Winckler, W., Getz, G., Frank, D., Hahn, W.C., Eck, M.J., Mani, D.R., Jaffe, J.D., Carr, S.A., Wong, K.K. and Meyerson, M.
Proceedings of the National Academy of Sciences of the United States of America 109
(36): 14476-14481.
4 September 2012
Predictors of adverse outcome in adolescents and adults with isolated left ventricular noncompaction.
Greutmann, M., Mah, M.L., Silversides, C.K., Klaassen, S., Attenhofer Jost, C.H., Jenni, R. and Oechslin, E.N.
American Journal of Cardiology 109
(2): 276-281.
15 January 2012
Short-term weightlessness produced by parabolic flight maneuvers altered gene expression patterns in human endothelial cells.
Grosse, J., Wehland, M., Pietsch, J., Ma, X., Ulbrich, C., Schulz, H., Saar, K., Huebner, N., Hauslage, J., Hemmersbach, R., Braun, M., van Loon, J., Vagt, N., Infanger, M., Eilles, C., Egli, M., Richter, P., Baltz, T., Einspanier, R., Sharbati, S. and Grimm, D.
FASEB Journal 26
(2): 639-655.
February 2012
Gravity-sensitive signaling drives 3-dimensional formation of multicellular thyroid cancer spheroids.
Grosse, J., Wehland, M., Pietsch, J., Schulz, H., Saar, K., Huebner, N., Eilles, C., Bauer, J., Abou-El-Ardat, K., Baatout, S., Ma, X., Infanger, M., Hemmersbach, R. and Grimm, D.
FASEB Journal 26
(12): 5124-5140.
December 2012
Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort.
Grote, V.A., Kaaks, R., Nieters, A., Tjonneland, A., Halkjaer, J., Overvad, K., Skjelbo Nielsen, M.R., Boutron-Ruault, M.C., Clavel-Chapelon, F., Racine, A., Teucher, B., Becker, S., Pischon, T., Boeing, H., Trichopoulou, A., Cassapa, C., Stratigakou, V., Palli, D., Krogh, V., Tumino, R., Vineis, P., Panico, S., Rodríguez, L., Duell, E.J., Sanchez, M.J., Dorronsoro, M., Navarro, C., Gurrea, A.B., Siersema, P.D., Hm Peeters, P., Ye, W., Sund, M., Lindkvist, B., Johansen, D., Khaw, K.T., Wareham, N., Allen, N.E., Travis, R.C., Fedirko, V., Jenab, M., Michaud, D.S., Chuang, S.C., Romaguera, D., Bueno-de-Mesquita, H.B. and Rohrmann, S.
British Journal of Cancer 106
(11): 1866-1874.
22 May 2012
Value of cardiovascular MR in diagnosing left ventricular non-compaction cardiomyopathy and in discriminating between other cardiomyopathies.
Grothoff, M., Pachowsky, M., Hoffmann, J., Posch, M., Klaassen, S., Lehmkuhl, L. and Gutberlet, M.
European Radiology 22
(12): 2699-2709.
December 2012
Interdisziplinaere Tumorkonferenzen : regionale und ueberregionale telemedizinische und teleradiologische Anbindung von Tumorzentren [Interdisciplinary tumor boards : regional and supraregional telemedical and teleradiological links to tumor boards].
Guettler, F.V., Rakowsky, S., Nagel, S.N., Teichgraeber, U. and Schlag, P.M.
Onkologe 18
(5): 389-397.
May 2012
Exercise induces renin-angiotensin system unbalance and high collagen expression in the heart of Mas-deficient mice.
Guimaraes, G.G., Santos, S.H.S., Oliveira, M.L., Pimenta-Veloso, E.P., Motta, D.F., Martins, A.S., Alenina, N., Bader, M., Santos, R.A.S. and Campagnole-Santos, M.J.
Peptides 38
(1): 54-61.
November 2012
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.
Guo, W., Schafer, S., Greaser, M.L., Radke, M.H., Liss, M., Govindarajan, T., Maatz, H., Schulz, H., Lincoln, S.E., Parrish, A.M., Dauksaite, V., Vakeel, P., Klaassen, S., Gerull, B., Thierfelder, L., Regitz-Zagrosek, V., Hacker, T.A., Saupe, K.W., Dec, G.W., Ellinor, P.T., MacRae, C.A., Spallek, B., Fischer, R., Perrot, A., Ozcelik, C., Saar, K., Hubner, N. and Gotthardt, M.
Nature Medicine 18
(5): 766-773.
May 2012
Prediction of transcription factor binding sites by integrating DNase digestion and histone modification.
Gusmao, E.G., Dieterich, C. and Costa, I.G.
Lecture Notes in Computer Science 7409
: 109-119.
2012
Variations in truncal body circumferences affect fat mass quantification with bioimpedance analysis.
Haas, V., Engeli, S., Hofmann, T., Riedl, A., Haufe, S., Kast, P., Wiesner, S., Boehnke, J., Jordan, J. and Boschmann, M.
European Journal of Clinical Nutrition 66
(2): 196-200.
February 2012
Bioimpedance and bioimpedance vector analysis in patients with anorexia nervosa.
Haas, V., Riedl, A., Hofmann, T., Nischan, A., Burghardt, R., Boschmann, M. and Klapp, B.
European Eating Disorders Review 20
(5): 400-405.
September 2012
Comparing single-frequency bioelectrical impedance analysis against deuterium dilution to assess total body water.
Haas, V., Schuetz, T., Engeli, S., Schroeder, C., Westerterp, K. and Boschmann, M.
European Journal of Clinical Nutrition 66
(9): 994-997.
September 2012
Multi-scale classification of disease using structural MRI and wavelet transform.
Hackmack, K., Paul, F., Weygandt, M., Allefeld, C. and Haynes, J.D.
NeuroImage 62
(1): 48-58.
1 August 2012
Can we overcome the 'clinico-radiological paradox' in multiple sclerosis?
Hackmack, K., Weygandt, M., Wuerfel, J., Pfueller, C.F., Bellmann-Strobl, J., Paul, F. and Haynes, J.D.
Journal of Neurology 259
(10): 2151-2160.
October 2012
Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.
Halff, E.F., Diebolder, C.A., Versteeg, M., Schouten, A., Brondijk, T.H.C. and Huizinga, E.G.
Journal of Biological Chemistry 287
(46): 38460-38472.
9 November 2012
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.
Hanna, J., Schütz, A., Zimmermann, F., Behlke, J., Sommer, T. and Heinemann, U.
Journal of Biological Chemistry 287
(11): 8633-8640.
9 March 2012
Presymptomatic alterations in energy metabolism and oxidative stress in the APP23 mouse model of Alzheimer disease.
Hartl, D., Schuldt, V., Forler, S., Zabel, C., Klose, J. and Rohe, M.
Journal of Proteome Research 11
(6): 3295-3304.
8 May 2012
Left ventricular mass and function with reduced-fat or reduced-carbohydrate hypocaloric diets in overweight and obese subjects.
Haufe, S., Utz, W., Engeli, S., Kast, P., Boehnke, J., Pofahl, M., Traber, J., Haas, V., Hermsdorf, M., Mähler, A., Busjahn, A., Wiesner, S., Otto, C., Mehling, H., Luft, F.C., Boschmann, M., Schulz-Menger, J. and Jordan, J.
Hypertension 59
(1): 70-75.
January 2012
Rationale and design of the Prevention of Cardiac Dysfunction During an Adjuvant Breast Cancer Therapy (PRADA) Trial.
Heck, S.L., Gulati, G., Ree, A.H., Schulz-Menger, J., Gravdehaug, B., Rosjo, H., Steine, K., Bratland, A., Hoffmann, P., Geisler, J. and Omland, T.
Cardiology 123
(4): 240-247.
30 November 2012
KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man.
Heidenreich, M., Lechner, S.G., Vardanyan, V., Wetzel, C., Cremers, C.W., De Leenheer, E.M., Aranguez, G., Moreno-Pelayo, M.A., Jentsch, T.J. and Lewin, G.R.
Nature Neuroscience 15
(1): 138-145.
2012
The biochemical anatomy of cortical inhibitory synapses.
Heller, E.A., Zhang, W., Selimi, F., Earnheart, J.C., Slimak, M.A., Santos-Torres, J., Ibanez-Tallon, I., Aoki, C., Chait, B.T. and Heintz, N.
PLoS ONE 7
(6): e39572.
29 June 2012
Repetitive magnetic stimulation of human-derived neuron-like cells activates cAMP-CREB pathway.
Hellmann, J., Juettner, R., Roth, C., Bajbouj, M., Kirste, I., Heuser, I., Gertz, K., Endres, M. and Kronenberg, G.
European Archives of Psychiatry and Clinical Neuroscience 262
(1): 87-91.
February 2012
Retinoic acid as target for local pharmacokinetic interaction with modafinil in neural cells.
Hellmann-Regen, J., Gertz, K., Uhlemann, R., Colla, M., Endres, M. and Kronenberg, G.
European Archives of Psychiatry and Clinical Neuroscience 262
(8): 697-704.
December 2012
Prediction of long-term outcome in glycine encephalopathy: a clinical survey.
Hennermann, J.B., Berger, J.M., Grieben, U., Scharer, G. and Van Hove, J.L.K.
Journal of Inherited Metabolic Disease 35
(2): 253-61.
March 2012
A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule.
Hennings, J.C., Picard, N., Huebner, A.K., Stauber, T., Maier, H., Brown, D., Jentsch, T.J., Vargas-Poussou, R., Eladari, D. and Huebner, C.A.
EMBO Molecular Medicine 4
(10): 1057-1071.
October 2012
A role for GPx3 in activity of normal and leukemia stem cells.
Herault, O., Hope, K.J., Deneault, E., Mayotte, N., Chagraoui, J., Wilhelm, B.T., Cellot, S., Sauvageau, M., Andrade-Navarro, M.A., Hebert, J. and Sauvageau, G.
Journal of Experimental Medicine 209
(5): 895-901.
7 May 2012
The sorting receptor sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells.
Herda, S., Raczkowski, F., Mittruecker, H.W., Willimsky, G., Gerlach, K., Kuehl, A.A., Breiderhoff, T., Willnow, T.E., Doerken, B., Höpken, U.E. and Rehm, A.
Immunity 37
(5): 854-866.
16 November 2012
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.
Herse, F., LaMarca, B., Hubel, C.A., Kaartokallio, T., Lokki, A.I., Ekholm, E., Laivuori, H., Gauster, M., Huppertz, B., Sugulle, M., Ryan, M.J., Novotny, S., Brewer, J., Park, J.K., Kacik, M., Hoyer, J., Verlohren, S., Wallukat, G., Rothe, M., Luft, F.C., Muller, D.N., Schunck, W.H., Staff, A.C. and Dechend, R.
Circulation 126
(25): 2990-2999.
18 December 2012
High spatial resolution and temporally resolved t(2) (*) mapping of normal human myocardium at 7.0 tesla: an ultrahigh field magnetic resonance feasibility study.
Hezel, F., Thalhammer, C., Waiczies, S., Schulz-Menger, J. and Niendorf, T.
PLoS ONE 7
(12): e52324.
14 December 2012
The Kallikrein-Kinin system.
Hillmeister, P. and Persson, P.B.
Acta Physiologica 206
(4): 215-219.
December 2012
A distinct metabolic signature predicts development of fasting plasma glucose.
Hische, M., Larhlimi, A., Schwarz, F., Fischer-Rosinsky, A., Bobbert, T., Assmann, A., Catchpole, G.S., Pfeiffer, A.F.H., Willmitzer, L., Selbig, J. and Spranger, J.
Journal of Clinical Bioinformatics 2
: 3.
2 February 2012
Rare copy number variants contribute to congenital left-sided heart disease.
Hitz, M.P., Lemieux-Perreault, L.P., Marshall, C., Feroz-Zada, Y., Davies, R., Yang, S.W., Lionel, A.C., D'Amours, G., Lemyre, E., Cullum, R., Bigras, J.L., Thibeault, M., Chetaille, P., Montpetit, A., Khairy, P., Overduin, B., Klaassen, S., Hoodless, P., Awadalla, P., Hussin, J., Idaghdour, Y., Nemer, M., Stewart, A.F., Boerkoel, C., Scherer, S.W., Richter, A., Dube, M.P. and Andelfinger, G.
PLoS Genetics 8
(9): e1002903.
6 September 2012
A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease.
Hofgaard, P.O., Jodal, H.C., Bommert, K., Huard, B., Caers, J., Carlsen, H., Schwarzer, R., Schuenemann, N., Jundt, F., Lindeberg, M.M. and Bogen, B.
PLoS ONE 7
(12): e51892.
20 December 2012
Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.
Horatscheck, A., Wagner, S., Ortwein, J., Kim, B.G., Lisurek, M., Beligny, S., Schuetz, A. and Rademann, J.
Angewandte Chemie International Edition 51
(37): 9441-9447.
10 September 2012
Mechanism for targeting the A-kinase anchoring protein AKAP18δ to the membrane.
Horner, A., Goetz, F., Tampe, R., Klussmann, E. and Pohl, P.
Journal of Biological Chemistry 287
(51): 42495-42501.
14 December 2012
A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function.
Hussain, M.S., Baig, S.M., Neumann, S., Nürnberg, G., Farooq, M., Ahmad, I., Alef, T., Hennies, H.C., Technau, M., Altmüller, J., Frommolt, P., Thiele, H., Noegel, A.A. and Nürnberg, P.
American Journal of Human Genetics 90
(5): 871-8.
4 May 2012
Tethering toxins and peptide ligands for modulation of neuronal function.
Ibanez-Tallon, I. and Nitabach, M.N.
Current Opinion in Neurobiology 22
(1): 72-78.
February 2012
Genome-wide association study of lung function decline in adults with and without asthma.
Imboden, M., Bouzigon, E., Curjuric, I., Ramasamy, A., Kumar, A., Hancock, D.B., Wilk, J.B., Vonk, J.M., Thun, G.A., Siroux, V., Nadif, R., Monier, F., Gonzalez, J.R., Wjst, M., Heinrich, J., Loehr, L.R., Franceschini, N., North, K.E., Altmüller, J., Koppelman, G.H., Guerra, S., Kronenberg, F., Lathrop, M., Moffatt, M.F., O'Connor, G.T., Strachan, D.P., Postma, D.S., London, S.J., Schindler, C., Kogevinas, M., Kauffmann, Fr., Jarvis, D.L., Demenais, F. and Probst-Hensch, N.M.
Journal of Allergy and Clinical Immunology 129
(5): 1218-28.
May 2012
CCR7 with S1P(1) signaling through AP-1 for migration of Foxp3(+) regulatory T-cells controls autoimmune exocrinopathy.
Ishimaru, N., Yamada, A., Nitta, T., Arakaki, R., Lipp, M., Takahama, Y. and Hayashi, Y.
American Journal of Pathology 180
(1): 199-208.
January 2012
HOXB4 can enhance the differentiation of embryonic stem cells by modulating the haematopoietic niche.
Jackson, M., Axton, R.A., Taylor, A.H., Wilson, J.A., Gordon-Keylock, S.A., Kokkaliaris, K., Brickman, J.M., Schulz, H., Hummel, O., Hubner, N. and Forrester, L.M.
Stem Cells 30
(2): 150-160.
February 2012
Testing for antibodies to human aquaporin-4 by ELISA: sensitivity, specificity, and direct comparison with immunohistochemistry.
Jarius, S., Franciotta, D., Paul, F., Bergamaschi, R., Rommer, P.S., Ruprecht, K., Ringelstein, M., Aktas, O., Kristoferitsch, W. and Wildemann, B.
Journal of the Neurological Sciences 320
(1-2): 32-37.
15 September 2012
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients.
Jarius, S., Ruprecht, K., Wildemann, B., Kuempfel, T., Ringelstein, M., Geis, C., Kleiter, I., Kleinschnitz, C., Berthele, A., Brettschneider, J., Hellwig, K., Hemmer, B., Linker, R.A., Lauda, F., Mayer, C.A., Tumani, H., Melms, A., Trebst, C., Stangel, M., Marziniak, M., Hoffmann, F., Schippling, S., Faiss, J.H., Neuhaus, O., Ettrich, B., Zentner, C., Guthke, K., Hofstadt-van Oy, U., Reuss, R., Pellkofer, H., Ziemann, U., Kern, P., Wandinger, K.P., Bergh, F.T., Boettcher, T., Langel, S., Liebetrau, M., Rommer, P.S., Niehaus, S., Muench, C., Winkelmann, A., Zettl U, U.K., Metz, I., Veauthier, C., Sieb, J.P., Wilke, C., Hartung, H.P., Aktas, O. and Paul, F.
Journal of Neuroinflammation 9
: 14.
19 January 2012
Influence of age, performance status, cancer activity, and IL-6 on anxiety and depression in patients with metastatic breast cancer.
Jehn, C.F., Flath, B., Strux, A., Krebs, M., Possinger, K., Pezzutto, A. and Lueftner, D.
Breast Cancer Research and Treatment 136
(3): 789-794.
December 2012
Chemical composition and biological activity of Paris quadrifolia L.
Jenett-Siems, K., Krause, N., Siems, K., Jakupovic, S., Wallukat, G. and Melzig, M.F.
Zeitschrift fuer Naturforschung C 67
(11-12): 565-570.
November 2012
CD19+CD5+ cells as indicators of preeclampsia.
Jensen, F., Wallukat, G., Herse, F., Budner, O., El-Mousleh, T., Costa, S.D., Dechend, R. and Zenclussen, A.C.
Hypertension 59
(4): 861-868.
April 2012
GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit.
Jeworutzki, E., Lopez-Hernandez, T., Capdevila-Nortes, X., Sirisi, S., Bengtsson, L., Montolio, M., Zifarelli, G., Arnedo, T., Mueller, C.S., Schulte, U., Nunes, V., Martinez, A., Jentsch, T.J., Gasull, X., Pusch, M. and Estevez, R.
Neuron 73
(5): 951-961.
8 March 2012
Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development.
John, A., Brylka, H., Wiegreffe, C., Simon, R., Liu, P., Juettner, R., Crenshaw, E.B., Luyten, F.P., Jenkins, N.A., Copeland, N.G., Birchmeier, C. and Britsch, S.
Development 139
(10): 1831-1841.
15 May 2012
Sleeping Beauty transposon-mediated transfection of retinal and iris pigment epithelial cells.
Johnen, S., Izsvak, Z., Stocker, M., Harmening, N., Salz, A.K., Walter, P. and Thumann, G.
Investigative Ophthalmology & Visual Science 53
(8): 4787-4796.
18 July 2012
Effect of cytochrome P450-dependent epoxyeicosanoids on Ristocetin-induced thrombocyte aggregation.
Jung, F., Schulz, C., Blaschke, F., Muller, D.N., Mrowietz, C., Franke, R.P., Lendlein, A. and Schunck, W.H.
Clinical Hemorheology and Microcirculation 52
(2-4): 403-416.
2012
Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers.
Kaden, D., Harmeier, A., Weise, C., Munter, L.M., Althoff, V., Rost, B.R., Hildebrand, P.W., Schmitz, D., Schaefer, M., Lurz, R., Skodda, S., Yamamoto, R., Arlt, S., Finckh, U. and Multhaup, G.
EMBO Molecular Medicine 4
(7): 647-659.
July 2012
Reduced tumor-antigen density leads to PD-1/PD-L1 mediated impairment of partially exhausted CD8(+) T cells.
Kaiser, A.D., Schuster, K., Gadiot, J., Borkner, L., Daebritz, H., Schmitt, C., Andreesen, R. and Blank, C.
European Journal of Immunology 42
(3): 662-671.
March 2012
Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
Kaji, T., Ishige, A., Hikida, M., Taka, J., Hijikata, A., Kubo, M., Nagashima, T., Takahashi, Y., Kurosaki, T., Okada, M., Ohara, O., Rajewsky, K. and Takemori, T.
Journal of Experimental Medicine 209
(11): 2079-2097.
22 October 2012
Plasmacytoid dendritic cells and Toll-like receptor 7-dependent signalling promote efficient protection of mice against highly virulent influenza A virus.
Kaminski, M.M., Ohnemus, A., Cornitescu, M. and Staeheli, P.
Journal of General Virology 93
(Pt 3): 555-559.
March 2012
B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin).
Kammertoens, T., Qin, Z., Briesemeister, D., Bendelac, A. and Blankenstein, T.
International Journal of Cancer 131
(7): 1499-1508.
1 October 2012
Endocytosis genes facilitate protein and membrane transport in C. elegans sensory cilia.
Kaplan, O.I., Doroquez, D.B., Cevik, S., Bowie, R.V., Clarke, L., Sanders, A.A.W.M., Kida, K., Rappoport, J.Z., Sengupta, P. and Blacque, O.E.
Current Biology 22
(6): 451-460.
20 March 2012
Proteolytic processing of the protein tyrosine phosphatase alpha extracellular domain is mediated by ADAM17/TACE.
Kapp, K., Siemens, J., Haering, H.U. and Lammers, R.
European Journal of Cell Biology 91
(9): 687-693.
September 2012
Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.
Karanam, K., Kafri, R., Loewer, A. and Lahav, G.
Molecular Cell 47
(2): 320-329.
27 July 2012
Agonistic autoantibodies to the alpha(1)-adrenergic receptor and the beta(2)-adrenergic receptor in Alzheimer's and vascular dementia.
Karczewski, P., Hempel, P., Kunze, R. and Bimmler, M.
Scandinavian Journal of Immunology 75
(5): 524-530.
May 2012
Antibodies to the alpha(1)-adrenergic receptor cause vascular impairments in rat brain as demonstrated by magnetic resonance angiography.
Karczewski, P., Pohlmann, A., Wagenhaus, B., Wisbrun, N., Hempel, P., Lemke, B., Kunze, R., Niendorf, T. and Bimmler, M.
PLoS ONE 7
(7): e41602.
30 July 2012
The Drosophila translational control element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes.
Katzenberger, R.J., Rach, E.A., Anderson, A.K., Ohler, U. and Wassarman, D.A.
PLoS ONE 7
(9): e45009.
11 September 2012
Optic nerve head quantification in idiopathic intracranial hypertension by spectral domain OCT.
Kaufhold, F., Kadas, E.M., Schmidt, C., Kunte, H., Hoffmann, J., Zimmermann, H., Oberwahrenbrock, T., Harms, L., Polthier, K., Brandt, A.U. and Paul, F.
PLoS ONE 7
(5): e36965.
15 May 2012
The role of CCR7 in allergic airway inflammation induced by house dust mite exposure.
Kawakami, M., Narumoto, O., Matsuo, Y., Horiguchi, K., Horiguchi, S., Yamashita, N., Sakaguchi, M., Lipp, M., Nagase, T. and Yamashita, N.
Cellular Immunology 275
(1-2): 24-32.
January 2012
Transcriptional expression profile of cultured human embryonic stem cells in vitro and in vivo.
Keil, M., Siegert, A., Eckert, K., Gerlach, J., Haider, W. and Fichtner, I.
In Vitro Cellular & Developmental Biology Animal 48
(3): 165-174.
March 2012
Loss of UDP-N-acetylglucosamine 2-epimerase/ N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells.
Kemmner, W., Kessel, P., Sanchez-Ruderisch, H., Moeller, H., Hinderlich, S., Schlag, P.M. and Detjen, K.
FASEB Journal 26
(2): 938-946.
February 2012
Gastrointestinale Ursachen von metabolischer Alkalose [Metabolic alkalosis in patients with gastrointestinal fluid loss].
Kettritz, R.
Nephrologe 7
(6): 481-489.
November 2012
Genotypic testing in clinically defined HHT: would Osler approve or turn in his grave?
Kettritz, R., Hinrichs, C., Althoff, C.E. and Luft, F.C.
Journal of the Royal College of Physicians of Edinburgh 42
(2): 128-130.
June 2012
Please advise on infusing hydrochloric acid.
Kettritz, R. and Luft, F.C.
Clinical Kidney Journal 5
(6): 595-596.
December 2012
Who is teaching 'Fluid and Electrolytes'?
Kettritz, R. and Luft, F.C.
Clinical Kidney Journal 5
(3): 269-271.
June 2012
Severe hypertension with large-vessel arteritis.
Kettritz, R. and Luft, F.C.
Hypertension 59
(2): 179-183.
February 2012
Clinical cardiac safety profile of nilotinib.
Kim, T.D., le Coutre, P., Schwarz, M., Grille, P., Levitin, M., Fateh-Moghadam, S., Giles, F.J., Doerken, B., Haverkamp, W. and Koehncke, C.
Haematologica 97
(6): 883-889.
June 2012
Group II metabotropic glutamate receptors depress synaptic transmission onto subicular burst firing neurons.
Kintscher, M., Breustedt, J., Miceli, S., Schmitz, D. and Wozny, C.
PLoS ONE 7
(9): e45039.
11 September 2012
Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Kirchner, F., Schuetz, A., Boldt, L.H., Martens, K., Dittmar, G., Haverkamp, W., Thierfelder, L., Heinemann, U. and Gerull, B.
Circulation Cardiovascular Genetics 5
(4): 400-411.
1 August 2012
In vivo quantitative proteome profiling: planning and evaluation of SILAC experiments.
Kirchner, M. and Selbach, M.
Methods in Molecular Biology 893
: 175-199.
7 May 2012
Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.
Klaus, A., Mueller, M., Schulz, H., Saga, Y., Martin, J.F. and Birchmeier, W.
Proceedings of the National Academy of Sciences of the United States of America 109
(27): 10921-10926.
3 July 2012
Failure of natalizumab to prevent relapses in neuromyelitis optica.
Kleiter, I., Hellwig, K., Berthele, A., Kuempfel, T., Linker, R.A., Hartung, H.P., Paul, F. and Aktas, O.
Archives of Neurology 69
(2): 239-245.
February 2012
In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis.
Klymiuk, I., Kenner, L., Adler, T., Busch, D.H., Boersma, A., Irmler, M., Fridrich, B., Gailus-Durner, V., Fuchs, H., Leitner, N., Mueller, M., Kuehn, R., Schlederer, M., Treise, I., de Angelis, M.H. and Beckers, J.
PLoS ONE 7
(10): e44609.
24 October 2012
Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis.
Knuppel, S., Esparza-Gordillo, J., Marenholz, I., Holzhutter, H., Bauerfeind, A., Ruether, A., Weidinger, S., Lee, Y.A. and Rohde, K.
BMC Medical Genetics 13
(1): 8.
27 January 2012
Differential effects of cystathionine-gamma-lyase-dependent vasodilatory H(2)S in periadventitial vasoregulation of rat and mouse aortas.
Koehn, C., Schleifenbaum, J., Szijártó, I.A., Marko, L., Dubrovska, G., Huang, Y. and Gollasch, M.
PLoS ONE 7
(8): e41951.
3 August 2012
The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria.
Koerner, C., Barrera, M., Dukanovic, J., Eydt, K., Harner, M., Rabl, R., Vogel, F., Rapaport, D., Neupert, W. and Reichert, A.S.
Molecular Biology of the Cell 23
(11): 2143-2155.
June 2012
23Na magnetic resonance imaging of tissue sodium.
Kopp, C., Linz, P., Wachsmuth, L., Dahlmann, A., Horbach, T., Schoefl, C., Renz, W., Santoro, D., Niendorf, T., Mueller, D.N., Neininger, M., Cavallaro, A., Eckardt, K.U., Schmieder, R.E., Luft, F.C., Uder, M. and Titze, J.
Hypertension 59
(1): 167-172.
January 2012
Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma.
Kopp, J.L., von Figura, G., Mayes, E., Liu, F.F., Dubois, C.L., Morris, J.P., Pan, F.C., Akiyama, H., Wright, C.V.E., Jensen, K., Hebrok, M. and Sander, M.
Cancer Cell 22
(6): 737-50.
11 December 2012
Activation of serotonin receptors promotes microglial injury-induced motility but attenuates phagocytic activity.
Krabbe, G., Matyiash, V., Pannasch, U., Mamer, L., Boddeke, H.W.G.M. and Kettenmann, H.
Brain Behavior and Immunity 26
(3): 419-428.
March 2012
Combination therapy with the albumin-binding prodrug of doxorubicin (INNO-206) and doxorubicin achieves complete remissions and improves tolerability in an ovarian A2780 xenograft model.
Kratz, F., Fichtner, I. and Graeser, R.
Investigational New Drugs 30
(4): 1743-1749.
August 2012
Green tea halts progression of cardiac transthyretin amyloidosis: an observational report.
Kristen, A.V., Lehrke, S., Buss, S., Mereles, D., Steen, H., Ehlermann, P., Hardt, S., Giannitsis, E., Schreiner, R., Haberkorn, U., Schnabel, P.A., Linke, R.P., Roecken, C., Wanker, E.E., Dengler, T.J., Altland, K. and Katus, H.A.
Clinical Research in Cardiology 101
(10): 805-813.
October 2012
Laser fusion of mouse embryonic cells and intra-embryonic fusion of blastomeres without affecting the embryo integrity.
Krivokharchenko, A., Karmenyan, A., Sarkisov, O., Bader, M., Chiou, A. and Shakhbazyan, A.
PLoS ONE 7
(12): e50029.
5 December 2012
Exofocal dopaminergic degeneration as antidepressant target in mouse model of poststroke depression.
Kronenberg, G., Balkaya, M., Prinz, V., Gertz, K., Ji, S., Kirste, I., Heuser, I., Kampmann, B., Hellmann-Regen, J., Gass, P., Sohr, R., Hellweg, R., Waeber, C., Juckel, G., Hoertnagl, H., Stumm, R. and Endres, M.
Biological Psychiatry 72
(4): 273-281.
15 August 2012
Structural basis for chirality and directional motility of Plasmodium sporozoites.
Kudryashev, M., Münter, S., Lemgruber, L., Montagna, G., Stahlberg, H., Matuschewski, K., Meissner, M., Cyrklaff, M. and Frischknecht, F.
Cellular Microbiology 14
(11): 1757-1768.
November 2012
Assessing the benefits of focal pair cryo-electron tomography.
Kudryashev, M., Stahlberg, H. and Castaño-Díez, D.
Journal of Structural Biology 178
(2): 88-97.
May 2012
Long-term lanreotide treatment in six patients with congenital hyperinsulinism.
Kuehnen, P., Marquard, J., Ernert, A., Meissner, T., Raile, K., Wannenmacher, G. and Blankenstein, O.
Hormone Research in Paediatrics 78
(2): 106-112.
September 2012
An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity.
Kuehnen, P., Mischke, M., Wiegand, S., Sers, C., Horsthemke, B., Lau, S., Keil, T., Lee, Y.A., Grueters, A. and Krude, H.
PLoS Genetics 8
(3): e1002543.
15 March 2012
STITCH 3: zooming in on protein-chemical interactions.
Kuhn, M., Szklarczyk, D., Franceschini, A., von Mering, C., Jensen, L.J. and Bork, P.
Nucleic Acids Research 40
(Database Issue): D876-D880.
January 2012
MOCAT: A Metagenomics Assembly and Gene Prediction Toolkit.
Kultima, J.R., Sunagawa, S., Li, J., Chen, W., Chen, H., Mende, D.R., Arumugam, M., Pan, Q., Liu, B., Qin, J., Wang, J. and Bork, P.
PLoS ONE 7
(10): e47656.
17 October 2012
Genetic models of Parkinson's disease.
Kühn, R., Vogt-Weisenhorn, D. and Wurst, W.
NeuroMethods 61
: 243-265.
2012
Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.
Künkele, A., De Preter, K., Heukamp, L., Thor, T., Pajtler, K.W., Hartmann, W., Mittelbronn, M., Grotzer, M.A., Deubzer, H.E., Speleman, F., Schramm, A., Eggert, A. and Schulte, J.H.
Neuro-Oncology 14
(7): 859-869.
1 July 2012
Uncoupling of PI3K from ErbB3 impairs mammary gland development but does not impact on ErbB2-induced mammary tumorigenesis.
Lahlou, H., Mueller, T., Sanguin-Gendreau, V., Birchmeier, C. and Muller, W.J.
Cancer Research 72
(12): 3080-3090.
15 June 2012
R-CHIE: a web server and R package for visualizing RNA secondary structures.
Lai, D., Proctor, J.R., Zhu, J.Y.A. and Meyer, I.M.
Nucleic Acids Research 40
(12): e95.
July 2012
Translocation of sickle cell erythrocyte microRNAs into plasmodium falciparum inhibits parasite rranslation and contributes to malaria resistance.
Lamonte, G., Philip, N., Reardon, J., Lacsina, J.R., Majoros, W., Chapman, L., Thornburg, C.D., Telen, M.J., Ohler, U., Nicchitta, C.V., Haystead, T. and Chi, J.T.
Cell Host & Microbe 12
(2): 187-199.
16 August 2012
The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome.
Lamprecht, B., Kreher, S., Moebs, M., Sterry, W., Doerken, B., Janz, M., Assaf, C. and Mathas, S.
British Journal of Dermatology 167
(2): 240-246.
August 2012
Multi-compartmental modeling of SORLA's influence on amyloidogenic processing in Alzheimer's disease.
Lao, A., Schmidt, V., Schmitz, Y., Willnow, T.E. and Wolkenhauer, O.
BMC Systems Biology 6
(1): 74.
22 June 2012
Regulation of ASIC channels by a stomatin/STOML3 complex located in a mobile vesicle pool in sensory neurons.
Lapatsina, L., Jira, J.A., Smith, E.S.J., Poole, K., Kozlenkov, A., Bilbao, D., Lewin, G.R. and Heppenstall, P.A.
Open Biology 2
(6): 120096.
27 June 2012
Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.
Lazaroni, T.L.N., Raslan, A.C.S., Fontes, W.R.P., de Oliveira, M.L., Bader, M., Alenina, N., Moraes, M.F.D., Dos Santos, R.A. and Pereira, G.S.
Neurobiology of Learning and Memory 97
(1): 113-123.
January 2012
Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype.
Lee, A.W.S., Hengstler, H., Schwald, K., Berriel-Diaz, M., Loreth, D., Kirsch, M., Kretz, O., Haas, C.A., Hrabe de Angelis, M., Herzig, S., Bruemmendorf, T., Klingenspor, M., Rathjen, F.G., Rozman, J., Nicholson, G., Cox, R.D. and Schaefer, M.K.E.
PLoS ONE 7
(7): e41537.
23 July 2012
Humanized c-Myc mouse.
Lehmann, F.M., Feicht, S., Helm, F., Maurberger, A., Ladinig, C., Zimber-Strobl, U., Kuehn, R., Mautner, J., Gerbitz, A. and Bornkamm, G.W.
PLoS ONE 7
(7): e42021.
31 July 2012
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann, S.M., Krueger, C., Park, B., Derkow, K., Rosenberger, K., Baumgart, J., Trimbuch, T., Eom, G., Hinz, M., Kaul, D., Habbel, P., Kaelin, R., Franzoni, E., Rybak, A., Nguyen, D., Veh, R., Ninnemann, O., Peters, O., Nitsch, R., Heppner, F.L., Golenbock, D., Schott, E., Ploegh, H.L., Wulczyn, F.G. and Lehnardt, S.
Nature Neuroscience 15
(6): 827-835.
June 2012
Extracellularly delivered single-stranded viral RNA causes neurodegeneration dependent on TLR7.
Lehmann, S.M., Rosenberger, K., Krueger, C., Habbel, P., Derkow, K., Kaul, D., Rybak, A., Brandt, C., Schott, E., Wulczyn, F.G. and Lehnardt, S.
Journal of Immunology 189
(3): 1448-1458.
1 August 2012
Thiamine is a substrate of organic cation transporters in Caco-2 cells.
Lemos, C., Faria, A., Meireles, M., Martel, F., Monteiro, R. and Calhau, C.
European Journal of Pharmacology 682
(1-3): 37-42.
5 May 2012
Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies.
Leu, C., de Kovel, C.G.F., Zara, F., Striano, P., Pezzella, M., Robbiano, A., Bianchi, A., Bisulli, F., Coppola, A., Giallonardo, A.T., Beccaria, F., Trenite, D.K., Lindhout, D., Gaus, V., Schmitz, B., Janz, D., Weber, Y.G., Becker, F., Lerche, H., Kleefuss-Lie, A.A., Hallman, K., Kunz, W.S., Elger, C.E., Muhle, H., Stephani, U., Moller, R.S., Hjalgrim, H., Mullen, S., Scheffer, I.E., Berkovic, S.F., Everett, K.V., Gardiner, M.R., Marini, C., Guerrini, R., Lehesjoki, A.E., Siren, A., Nabbout, R., Baulac, S., Leguern, E., Serratosa, J.M., Rosenow, F., Feucht, M., Unterberger, I., Covanis, A., Suls, A., Weckhuysen, S., Kaneva, R., Caglayan, H., Turkdogan, D., Baykan, B., Bebek, N., Ozbek, U., Hempelmann, A., Schulz, H., Rueschendorf, F., Trucks, H., Nuernberg, P., Avanzini, G., Koeleman, B.P.C. and Sander, T.
Epilepsia 53
(2): 308-318.
February 2012
Educational level and risk of colorectal cancer in EPIC with specific reference to tumor location.
Leufkens, A.M., van Duijnhoven, F.J., Boshuizen, H.C., Siersema, P.D., Kunst, A.E., Mouw, T., Tjonneland, A., Olsen, A., Overvad, K., Boutron-Ruault, M.C., Clavel-Chapelon, F., Morois, S., Krogh, V., Tumino, R., Panico, S., Polidoro, S., Palli, D., Kaaks, R., Teucher, B., Pischon, T., Trichopoulou, A., Orfanos, P., Goufa, I., Peeters, P.H., Skeie, G., Braaten, T., Rodriguez, L., Lujan-Barroso, L., Sanchez-Perez, M.J., Navarro, C., Barricarte, A., Zackrisson, S., Almquist, M., Hallmans, G., Palmqvist, R., Tsilidis, K.K., Khaw, K.T., Wareham, N., Gallo, V., Jenab, M., Riboli, E. and Bueno-de-Mesquita, H.B.
International Journal of Cancer 130
(3): 622-630.
1 February 2012
Biomarkers of oxidative stress and risk of developing colorectal cancer: a cohort-nested case-control study in the European Prospective Investigation Into Cancer and Nutrition.
Leufkens, A.M., van Duijnhoven, F.J.B., Woudt, S.H., Siersema, P.D., Jenab, M., Jansen, E.H.J.M., Pischon, T., Tjonneland, A., Olsen, A., Overvad, K., Boutron-Ruault, M.C., Clavel-Chapelon, F., Morois, S., Palli, D., Pala, V., Tumino, R., Vineis, P., Panico, S., Kaaks, R., Lukanova, A., Boeing, H., Aleksandrova, K., Trichopoulou, A., Trichopoulos, D., Dilis, V., Peeters, P.H., Skeie, G., Gonzalez, C.A., Argueelles, M., Sanchez, M.J., Dorronsoro, M., Huerta, J.M., Ardanaz, E., Hallmans, G., Palmqvist, R., Khaw, K.T., Wareham, N., Allen, N.E., Crowe, F.L., Fedirko, V., Norat, T., Riboli, E. and Bueno-de-Mesquita, H.B.
American Journal of Epidemiology 175
(7): 653-663.
1 April 2012
A polymorphic microsatellite repeat within the ECE-1c promoter is involved in transcriptional start site determination, human evolution, and Alzheimer's disease.
Li, Y., Seidel, K., Marschall, P., Klein, M., Hope, A., Schacherl, J., Schmitz, J., Menk, M., Schefe, J.H., Reinemund, J., Hugel, R., Walden, P., Schlosser, A., Volkmer, R., Schimkus, J., Koelsch, H., Maier, W., Kornhuber, J., Froelich, L., Klare, S., Kirsch, S., Schmerbach, K., Scheele, S., Grittner, U., Zollmann, F., Goldin-Lang, P., Peters, O., Kintscher, U., Unger, T. and Funke-Kaiser, H.
Journal of Neuroscience 32
(47): 16807-16820.
21 November 2012
Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29 000 subjects.
Lill, C.M., Liu, T., Schjeide, B.M., Roehr, J.T., Akkad, D.A., Damotte, V., Alcina, A., Ortiz, M.A., Arroyo, R., Lopez de Lapuente, A., Blaschke, P., Winkelmann, A., Gerdes, L.A., Luessi, F., Fernadez, O., Izquierdo, G., Antiguedad, A., Hoffjan, S., Cournu-Rebeix, I., Gromoeller, S., Faber, H., Liebsch, M., Meissner, E., Chanvillard, C., Touze, E., Pico, F., Corcia, P., Doerner, T., Steinhagen-Thiessen, E., Baeckman, L., Heekeren, H.R., Li, S.C., Lindenberger, U., Chan, A., Hartung, H.P., Aktas, O., Lohse, P., Kuempfel, T., Kubisch, C., Epplen, J.T., Zettl, U.K., Fontaine, B., Vandenbroeck, K., Matesanz, F., Urcelay, E., Bertram, L. and Zipp, F.
Journal of Medical Genetics 49
(9): 558-562.
September 2012
Energy demand of synaptic transmission at the hippocampal Schaffer-collateral synapse.
Liotta, A., Roesner, J., Huchzermeyer, C., Wojtowicz, A., Kann, O., Schmitz, D., Heinemann, U. and Kovacs, R.
Journal of Cerebral Blood Flow and Metabolism 32
(11): 2076-2083.
November 2012
Extraneous markers used for genetic similarity leads to loss of power in GWAS and heritability determination.
Lippert, C., Quon, G., Listgarten, J. and Heckerman, D.
3 December 2012
Genetic manipulations and examination of differentiation properties of rat induced pluripotent cells.
Liskovykh, M.A., Chuykin, I.A., Ranjan, A., Popova, E., Tolkunova, E.N., Chechik, L.L., Malinin, A.Y., Morozova, A.V., Mosienko, V., Bader, M., Alenina, N. and Tomilin, A.N.
Cell and Tissue Biology 6
(2): 122-127.
April 2012
Generation of rat-induced pluripotent stem cells: reprogramming and culture medium.
Liskovykh, M.A., Chuykin, I.A., Ranjan, A., Safina, D.A., Tolkunova, E.N., Minina, Y.M., Zhdanova, N.S., Dyban, P.A., Mullins, J.J., Kostyleva, E.I., Chikhirzhina, E.V., Bader, M., Alenina, N. and Tomilin, A.N.
Cell and Tissue Biology 6
(2): 115-121.
April 2012
Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
Liu, L., Ulbrich, J., Mueller, J., Wuestefeld, T., Aeberhard, L., Kress, T.R., Muthalagu, N., Rycak, L., Rudalska, R., Moll, R., Kempa, S., Zender, L., Eilers, M. and Murphy, D.J.
Nature 483
(7391): 608-612.
29 March 2012
Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques.
Liu, X., Somel, M., Tang, L., Yan, Z., Jiang, X., Guo, S., Yuan, Y.P., He, L., Oleksiak, A., Zhang, Y., Li, N., Hu, Y., Chen, W., Qiu, Z., Paeaebo, S. and Khaitovich, P.
Genome Research 22
(4): 611-622.
April 2012
The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling.
Liu, Y., Echtermeyer, F., Thilo, F., Theilmeier, G., Schmidt, A., Schuelein, R., Jensen, B.L., Loddenkemper, C., Jankowski, V., Marcussen, N., Gollasch, M., Arendshorst, W.J. and Tepel, M.
Arteriosclerosis Thrombosis and Vascular Biology 32
(2): 378-385.
February 2012
Cell tracking using photoconvertible proteins during zebrafish development.
Lombardo, V.A., Sporbert, A. and Abdelilah-Seyfried, S.
Journal of Visualized Experiments
(67): e4350.
28 September 2012
Rapid method for proline determination in grape juice and wine.
Long, D., Wilkinson, K.L., Poole, K., Taylor, D.K., Warren, T., Astorga, A.M. and Jiranek, V.
Journal of Agricultural and Food Chemistry 60
(17): 4259-4264.
2 May 2012
Structural properties of EGCG-induced, nontoxic Alzheimer's disease Aβ oligomers.
Lopez Del Amo, J.M., Fink, U., Dasari, M., Grelle, G., Wanker, E.E., Bieschke, J. and Reif, B.
Journal of Molecular Biology 421
(4-5): 517-524.
24 August 2012
Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity.
Lopez-Herrera, G., Tampella, G., Pan-Hammarström, Q., Herholz, P., Trujillo-Vargas, C.M., Phadwal, K., Simon, A.K., Moutschen, M., Etzioni, A., Mory, A., Srugo, I., Melamed, D., Hultenby, K., Liu, C., Baronio, M., Vitali, M., Philippet, P., Dideberg, V., Aghamohammadi, A., Rezaei, N., Enright, V., Du, L., Salzer, U., Eibel, H., Pfeifer, D., Veelken, H., Stauss, H., Lougaris, V., Plebani, A., Gertz, E.M., Schäffer, A.A., Hammarström, L. and Grimbacher, B.
American Journal of Human Genetics 90
(6): 986-1001.
8 June 2012
Mutations of ventricular essential myosin light chain disturb myosin binding and sarcomeric sorting.
Lossie, J., Ushakov, D.S., Ferenczi, M.A., Werner, S., Keller, S., Haase, H. and Morano, I.
Cardiovascular Research 93
(3): 390-396.
1 March 2012
Prediction of protein secondary structure from circular dichroism using theoretically derived spectra.
Louis-Jeune, C., Andrade-Navarro, M.A. and Perez-Iratxeta, C.
Proteins: Structure, Function, and Bioinformatics 80
(2): 374-381.
February 2012
Continuous glucose monitoring in children, adolescents, and adults with type 1 diabetes mellitus: analysis from the prospective DPV diabetes documentation and quality management system from Germany and Austria.
Ludwig-Seibold, C.U., Holder, M., Rami, B., Raile, K., Heidtmann, B. and Holl, R.W.
Pediatric Diabetes 13
(1): 12-14.
February 2012
Thiazolidinedione response in familial lipodystrophy patients with LMNA mutations: a case series.
Luedtke, A., Boschmann, M., Colpe, C., Engeli, S., Adams, F., Birkenfeld, A.L., Haufe, S., Rahn, G., Luft, F.C., Schmidt, H.H.J. and Jordan, J.
Hormone and Metabolic Research 44
(4): 306-311.
April 2012
Akute metabolische Azidose: Gruendlich ueberdenken - dann handeln [Acute metabolic acidosis. Thoroughly consider-then act!].
Luft, F.C.
Nephrologe 7
(6): 468-471.
November 2012
Renal ischemia and transplantation predispose to vascular constriction mediated by angiotensin II type 1 receptor-activating antibodies.
Lukitsch, I., Kehr, J., Chaykovska, L., Wallukat, G., Nieminen-Kelhae, M., Batuman, V., Dragun, D. and Gollasch, M.
Transplantation 94
(1): 8-13.
15 July 2012
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.
Luo, C., Gangadharan, V., Bali, K.K., Xie, R.G., Agarwal, N., Kurejova, M., Tappe-Theodor, A., Tegeder, I., Feil, S., Lewin, G., Polgar, E., Todd, A.J., Schlossmann, J., Hofmann, F., Liu, D.L., Hu, S.J., Feil, R., Kuner, T. and Kuner, R.
PLoS Biology 10
(3): e1001283.
13 March 2012
Pattern and density of vascularization in mammalian testes, ovaries, and ovotestes.
Lupianez, D.G., Real, F.M., Dadhich, R.K., Carmona, F.D., Burgos, M., Barrionuevo, F.J. and Jimenez, R.
Journal of Experimental Zoology Part B : Molecular and Developmental Evolution 318
(3): 170-181.
May 2012
A misplaced lncRNA causes brachydactyly in humans.
Maass, P.G., Rump, A., Schulz, H., Stricker, S., Schulze, L., Platzer, K., Aydin, A., Tinschert, S., Goldring, M.B., Luft, F.C. and Bähring, S.
Journal of Clinical Investigation 122
(11): 3990-4002.
1 November 2012
Ultrahigh-field MRI in human ischemic stroke - a 7 tesla study.
Madai, V.I., von Samson-Himmelstjerna, F.C., Bauer, M., Stengl, K.L., Mutke, M.A., Tovar-Martinez, E., Wuerfel, J., Endres, M., Niendorf, T. and Sobesky, J.
PLoS ONE 7
(5): e37631.
31 May 2012
Cannabinoids disrupt hippocampal sharp wave-ripples via inhibition of glutamate release.
Maier, N., Morris, G., Schuchmann, S., Korotkova, T., Ponomarenko, A., Boehm, C., Wozny, C. and Schmitz, D.
Hippocampus 22
(6): 1350-1362.
June 2012
Improving the quality of electron tomography image volumes using pre-reconstruction filtering.
Maiorca, M., Hanssen, E., Kazmierczak, E., Maco, B., Kudryashev, M., Hall, R., Quiney, H. and Tilley, L.
Journal of Structural Biology 180
(1): 132-142.
October 2012
Sarcolemmal repair is a slow process and includes EHD2.
Marg, A., Schoewel, V., Timmel, T., Schulze, A., Shah, C., Daumke, O. and Spuler, S.
Traffic 13
(9): 1286-1294.
September 2012
Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat, S., Schmidt, A., Codlin, S., Chen, W., Aebersold, R. and Baehler, J.
Cell 151
(3): 671-683.
26 October 2012
Angiotensin-(1-7) Mas-receptor deficiency decreases peroxisome proliferator-activated receptor gamma expression in adipocytes.
Mario, E.G., Santos, S.H.S., Ferreira, A.V.M., Bader, M., Santos, R.A.S. and Botion, L.M.
Peptides 33
(1): 174-177.
January 2012
Interferon-gamma signaling inhibition ameliorates angiotensin II-induced cardiac damage.
Marko, L., Kvakan, H., Park, J.K., Qadri, F., Spallek, B., Binger, K.J., Bowman, E.P., Kleinewietfeld, M., Fokuhl, V., Dechend, R. and Mueller, D.N.
Hypertension 60
(6): 1430-1436.
December 2012
How branching can change the conductance of ballistic semiconductor devices.
Maryenko, D., Ospald, F., von Klitzing, K., Smet, J.H., Metzger, J.J., Fleischmann, R., Geisel, T. and Umansky, V.
Physical Review B 85
(19): 195329.
31 May 2012
Proteome dynamics and early salt stress response of the photosynthetic organism Chlamydomonas reinhardtii.
Mastrobuoni, G., Irgang, S., Pietzke, M., Wenzel, M., Assmus, H.E., Schulze, W.X. and Kempa, S.
BMC Genomics 13
(1): 215.
31 May 2012
The Lin28 cold-shock domain remodels pre-let-7 microRNA.
Mayr, F., Schütz, A., Dge, N. and Heinemann, U.
Nucleic Acids Research 40
(15): 7492-7506.
1 August 2012
In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes.
McCann, M., Santos, A.L.S., da Silva, B.A., Romanos, M.T.V., Pyrrho, A.S., Devereux, M., Kavanagh, K., Fichtner, I. and Kellett, A.
Toxicology Research 1
(1): 47-54.
July 2012
The transcriptional landscape of hematopoietic stem cell ontogeny.
McKinney-Freeman, S., Cahan, P., Li, H., Lacadie, S.A., Huang, H.T., Curran, M., Loewer, S., Naveiras, O., Kathrein, K.L., Konantz, M., Langdon, E.M., Lengerke, C., Zon, L.I., Collins, J.J. and Daley, G.Q.
Cell Stem Cell 11
(5): 701-714.
2 November 2012
Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.
McNeill, B., Perez-Iratxeta, C., Mazerolle, C., Furimsky, M., Mishina, Y., Andrade-Navarro, M.A. and Wallace, V.A.
Molecular and Cellular Neuroscience 49
(3): 333-340.
March 2012
Quantification of collateral artery growth by automated fluorescent microsphere perfusion.
Meder, B., Bergmann, C.E., Keller, A., Just, S., Katus, H.A., Hoefer, I.E. and Buschmann, I.R.
International Journal of Cardiology 161
(2): 88-92.
15 November 2012
Assessment of metagenomic assembly using simulated next generation sequencing data.
Mende, D.R., Waller, A.S., Sunagawa, S., Jaervelin, A.I., Chan, M.M., Arumugam, M., Raes, J. and Bork, P.
PLoS ONE 7
(2): e31386.
23 February 2012
iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics.
Mertins, P., Udeshi, N.D., Clauser, K.R., Mani, D.R., Patel, J., Ong, S.E., Jaffe, J.D. and Carr, S.A.
Molecular & Cellular Proteomics 11
(6): M111.014423.
1 June 2012
Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10.
Meyer, I., Kunert, S., Schwiebert, S., Hagedorn, I., Italiano, J.E., Duetting, S., Nieswandt, B., Bachmann, S. and Schulze, H.
Blood 120
(17): 3594-602.
25 October 2012
Modeling disease mutations by gene targeting in one-cell mouse embryos.
Meyer, M., Ortiz, O., Hrabe de Angelis, M., Wurst, W. and Kuehn, R.
Proceedings of the National Academy of Sciences of the United States of America 109
(24): 9354-9359.
12 June 2012
Nestin expression identifies ependymoma patients with poor outcome.
Milde, T., Hielscher, T., Witt, H., Kool, M., Mack, S.C., Deubzer, H.E., Oehme, I., Lodrini, M., Benner, A., Taylor, M.D., von Deimling, A., Kulozik, A.E., Pfister, S.M., Witt, O. and Korshunov, A.
Brain Pathology 22
(6): 848-860.
November 2012
HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.
Milde, T., Lodrini, M., Savelyeva, L., Korshunov, A., Kool, M., Brueckner, L.M., Antunes, A.S.L.M., Oehme, I., Pekrun, A., Pfister, S.M., Kulozik, A.E., Witt, O. and Deubzer, H.E.
Journal of Neuro-Oncology 110
(3): 335-348.
December 2012
Deciphering a global network of functionally associated post-translational modifications.
Minguez, P., Parca, L., Diella, F., Mende, D.R., Kumar, R., Helmer-Citterich, M., Gavin, A.C., van Noort, V. and Bork, P.
Molecular Systems Biology 8
: 599.
17 July 2012
Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease.
Moeller, A., Xie, S.Q., Hosp, F., Lang, B., Phatnani, H.P., James, S., Ramirez, F., Collin, G.B., Naggert, J.K., Babu, M.M., Greenleaf, A.L., Selbach, M. and Pombo, A.
Molecular & Cellular Proteomics 11
(6): M111.011767.
June 2012
Hierarchic stochastic modelling applied to intracellular Ca(2+) signals.
Moenke, G., Falcke, M. and Thurley, K.
PLoS ONE 7
(12): e51178.
27 December 2012
Body iron stores and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study.
Montonen, J., Boeing, H., Steffen, A., Lehmann, R., Fritsche, A., Joost, H.G., Schulze, M.B. and Pischon, T.
Diabetologia 55
(10): 2613-2621.
October 2012
Reliability of fasting plasma alkylresorcinol metabolites concentrations measured 4 months apart.
Montonen, J., Landberg, R., Kamal-Eldin, A., Aman, P., Boeing, H., Steffen, A. and Pischon, T.
European Journal of Clinical Nutrition 66
(8): 968-970.
August 2012
EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization.
Moren, B., Shah, C., Howes, M.T., Schieber, N.L., McMahon, H.T., Parton, R.G., Daumke, O. and Lundmark, R.
Molecular Biology of the Cell 23
(7): 1316-1329.
9 February 2012
Kinin b(1) receptor in adipocytes regulates glucose tolerance and predisposition to obesity.
Mori, M.A., Sales, V.M., Motta, F.L., Fonseca, R.G., Alenina, N., Guadagnini, D., Schadock, I., Silva, E.D., Torres, H.A., Dos Santos, E.L., Castro, C.H., D'Almeida, V., Andreotti, S., Campana, A.B., Sertie, R.A., Saad, M.J., Lima, F.B., Bader, M. and Pesquero, J.B.
PLoS ONE 7
(9): e44782.
14 September 2012
Myocardial systolic and diastolic performance derived by 2-dimensional speckle tracking echocardiography in heart failure with normal left ventricular ejection fraction.
Morris, D.A., Boldt, L.H., Eichstaedt, H., Oezcelik, C. and Haverkamp, W.
Circulation Heart Failure 5
(5): 610-620.
September 2012
Myocardial systolic and diastolic consequences of left ventricular mechanical dyssynchrony in heart failure with normal left ventricular ejection fraction.
Morris, D.A., Vaz Perez, A., Blaschke, F., Eichstaedt, H., Ozcelik, C. and Haverkamp, W.
European Heart Journal - Cardiovascular Imaging 13
(7): 556-567.
July 2012
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes.
Morán, I., Akerman, I., van de Bunt, M., Xie, R., Benazra, M., Nammo, T., Arnes, L., Nakić, N., García-Hurtado, J., Rodríguez-Seguí, S., Pasquali, L., Sauty-Colace, C., Beucher, A., Scharfmann, R., van Arensbergen, J., Johnson, P.R., Berry, A., Lee, C., Harkins, T., Gmyr, V., Pattou, F., Kerr-Conte, J., Piemonti, L., Berney, T., Hanley, N., Gloyn, A.L., Sussel, L., Langman, L., Brayman, K.L., Sander, M., McCarthy, M.I., Ravassard, P. and Ferrer, J.
Cell Metabolism 16
(4): 435-48.
3 October 2012
Cost evaluation of cardiovascular magnetic resonance versus coronary angiography for the diagnostic work-up of coronary artery disease: application of the European Cardiovascular Magnetic Resonance registry data to the German, United Kingdom, Swiss, and United States health care systems.
Moschetti, K., Muzzarelli, S., Pinget, C., Wagner, A., Pilz, G., Wasserfallen, J.B., Schulz-Menger, J., Nothnagel, D., Dill, T., Frank, H., Lombardi, M., Bruder, O., Mahrholdt, H. and Schwitter, J.
Journal of Cardiovascular Magnetic Resonance 14
: 35.
14 June 2012
Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin.
Mosienko, V., Bert, B., Beis, D., Matthes, S., Fink, H., Bader, M. and Alenina, N.
Translational Psychiatry 2
(5): e122.
29 May 2012
Protective capacity of virus-specific T cell receptor (TCR)-transduced CD8 T cells in vivo.
Mueller, K., von Maessenhausen, A., Aichele, U., Staerck, L., Leisegang, M., Uckert, W. and Pircher, H.
Journal of Virology 86
(19): 10866-10869.
October 2012
Generation of mouse induced pluripotent stem cells from different genetic backgrounds using Sleeping beauty transposon mediated gene transfer.
Muenthaisong, S., Ujhelly, O., Polgar, Z., Varga, E., Ivics, Z., Pirity, M.K. and Dinnyes, A.
Experimental Cell Research 318
(19): 2482-2489.
15 November 2012
p14ARF-induced apoptosis in p53-deficient cells is mediated by the BH3-only protein independent de-repression of Bak through down-regulation of Mcl-1 and Bcl-xL.
Muer, A., Overkamp, T., Gillissen, B., Richter, A., Pretzsch, T., Milojkovic, A., Doerken, B., Daniel, P.T. and Hemmati, P.
Journal of Biological Chemistry 287
(21): 17343-17352.
18 May 2012
Diverse epigenetic strategies interact to control epidermal differentiation.
Mulder, K.W., Wang, X., Escriu, C., Ito, Y., Schwarz, R.F., Gillis, J., Sirokmany, G., Donati, G., Uribe-Lewis, S., Pavlidis, P., Murrell, A., Markowetz, F. and Watt, F.M.
Nature Cell Biology 14
(7): 753-763.
24 June 2012
Chronic Chagas' heart disease: a disease on its way to becoming a worldwide health problem: epidemiology, etiopathology, treatment, pathogenesis and laboratory medicine.
Munoz-Saravia, S.G., Haberland, A., Wallukat, G. and Schimke, I.
Heart Failure Reviews 17
(1): 45-64.
January 2012
Is metabolic flexibility altered in multiple sclerosis patients?
Mähler, A., Steiniger, J., Bock, M., Brandt, A.U., Haas, V., Boschmann, M. and Paul, F.
PLoS ONE 7
(8): e43675.
28 August 2012
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Naba, A., Clauser, K.R., Hoersch, S., Liu, H., Carr, S.A. and Hynes, R.O.
Molecular & Cellular Proteomics 11
(4): M111.014647.
1 April 2012
Adaptive space and time numerical simulation of reaction-diffusion models for intracellular calcium dynamics.
Nagaiah, C., Ruediger, S., Warnecke, G. and Falcke, M.
Applied Mathematics and Computation 218
(20): 10194-10210.
15 June 2012
Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Nagel, D., Spranger, S., Vincendeau, M., Grau, M., Raffegerst, S., Kloo, B., Hlahla, D., Neuenschwander, M., von Kries, J.P., Hadian, K., Doerken, B., Lenz, P., Lenz, G., Schendel, D.J. and Krappmann, D.
Cancer Cell 22
(6): 825-837.
11 December 2012
CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.
Nakamoto, N., Ebinuma, H., Kanai, T., Chu, P.S., Ono, Y., Mikami, Y., Ojiro, K., Lipp, M., Love, P.E., Saito, H. and Hibi, T.
Gastroenterology 142
(2): 366-376.
February 2012
Extrinsic notch ligand delta-like 1 regulates tip cell selection and vascular branching morphogenesis.
Napp, L.C., Augustynik, M., Paesler, F., Krishnasamy, K., Woiterski, J., Limbourg, A., Bauersachs, J., Drexler, H., le Noble, F. and Limbourg, F.P.
Circulation Research 110
(4): 530-550.
17 February 2012
Predicting cell-type-specific gene expression from regions of open chromatin.
Natarajan, A., Yardimci, G.G., Sheffield, N.C., Crawford, G.E. and Ohler, U.
Genome Research 22
(9): 1711-1722.
September 2012
The immediate early gene Ier2 promotes tumor cell motility and metastasis, and predicts poor survival of colorectal cancer patients.
Neeb, A., Wallbaum, S., Novac, N., Dukovic-Schulze, S., Scholl, I., Schreiber, C., Schlag, P., Moll, J., Stein, U. and Sleeman, J.P.
Oncogene 31
(33): 3796-3806.
August 2012
CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model.
Nguyen-Hoai, T., Baldenhofer, G., Ahmed, M.S., Pham-Duc, M., Gries, M., Lipp, M., Doerken, B., Pezzutto, A. and Westermann, J.
Journal of Gene Medicine 14
(2): 128-137.
February 2012
CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model.
Nguyen-Hoai, T., Baldenhofer, G., Sayed Ahmed, M.S., Pham-Duc, M., Vu, M.D., Lipp, M., Doerken, B., Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 19
(1): 69-76.
January 2012
CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: improved vaccine efficacy and a role for B cells as APC.
Nguyen-Hoai, T., Hohn, O., Vu, M.D., Baldenhofer, G., Sayed Ahmed, M.S., Doerken, B., Norley, S., Lipp, M., Pezzutto, A. and Westermann, J.
Cancer Gene Therapy 19
(12): 880-887.
December 2012
HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: gene gun is superior to jet injector in inducing CTL responses and protective immunity.
Nguyen-Hoai, T., Kobelt, D., Hohn, O., Vu, M.D., Schlag, P.M., Doerken, B., Norley, S., Lipp, M., Walther, W., Pezzutto, A. and Westermann, J.
OncoImmunology 1
(9): 1537-1545.
1 December 2012
Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage a multicenter prospective cohort study.
Nickolas, T.L., Schmidt-Ott, K.M., Canetta, P., Forster, C., Singer, E., Sise, M., Elger, A., Maarouf, O., Sola-Del Valle, D.A., O'Rourke, M., Sherman, E., Lee, P., Geara, A., Imus, P., Guddati, A., Polland, A., Rahman, W., Elitok, S., Malik, N., Giglio, J., El-Sayegh, S., Devarajan, P., Hebbar, S., Saggi, S.J., Hahn, B., Kettritz, R., Luft, F.C. and Barasch, J.
Journal of the American College of Cardiology 59
(3): 246-255.
17 January 2012
Association between plasma 25-OH vitamin D and testosterone levels in men.
Nimptsch, K., Platz, E.A., Willett, W.C. and Giovannucci, E.
Clinical Endocrinology 77
(1): 106-112.
July 2012
Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer.
Nitsche, U., Rosenberg, R., Balmert, A., Schuster, T., Slotta-Huspenina, J., Herrmann, P., Bader, F.G., Friess, H., Schlag, P.M., Stein, U. and Janssen, K.P.
Annals of Surgery 256
(5): 763-771.
November 2012
Krueppel-like factor 15 regulates Wnt/beta-catenin transcription and controls cardiac progenitor cell fate in the postnatal heart.
Noack, C., Zafiriou, M.P., Schaeffer, H.J., Renger, A., Pavlova, E., Dietz, R., Zimmermann, W.H., Bergmann, M.W. and Zelarayan, L.C.
EMBO Molecular Medicine 4
(9): 992-1007.
September 2012
Ensemble and single particle fluorimetric techniques in concerted action to study the diffusion and aggregation of the glycine receptor α3 isoforms in the cell plasma membrane.
Notelaers, K., Smisdom, N., Rocha, S., Janssen, D., Meier, J.C., Rigo, J.M., Hofkens, J. and Ameloot, M.
Biochimica et Biophysica Acta - Biomembranes 1818
(12): 3131-3140.
December 2012
Activating autoantibodies to the angiotensin receptor are important in mediating hypertension in response to adoptive transfer of RUPP CD4+ T lymphocytes.
Novotny, S.R., Wallace, K., Heath, J., Moseley, J., Dhillon, P., Weimer, A., Wallukat, G., Herse, F., Wenzel, K., Martin, J.N., Dechend, R. and Lamarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 302
(10): R1197-R1201.
15 May 2012
Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.
O'Connell, R.J., Thon, M.R., Hacquard, S., Amyotte, S.G., Kleemann, J., Torres, M.F., Damm, U., Buiate, E.A., Epstein, L., Alkan, N., Altmüller, J., Alvarado-Balderrama, L., Bauser, C.A., Becker, C., Birren, B.W., Chen, Z., Choi, J., Crouch, J.A., Duvick, J.P., Farman, M.A., Gan, P., Heiman, D., Henrissat, B., Howard, R.J., Kabbage, M., Koch, C., Kracher, B., Kubo, Y., Law, A.D., Lebrun, M.H., Lee, Y.H., Miyara, I., Moore, N., Neumann, U., Nordström, K., Panaccione, D.G., Panstruga, R., Place, M., Proctor, R.H., Prusky, D., Rech, G., Reinhardt, R., Rollins, J.A., Rounsley, S., Schardl, C.L., Schwartz, D.C., Shenoy, N., Shirasu, K., Sikhakolli, U.R., Stüber, K., Sukno, S.A., Sweigard, J.A., Takano, Y., Takahara, H., Trail, F., van der Does, H.C., Voll, L.M., Will, I., Young, S., Zeng, Q., Zhang, J., Zhou, S., Dickman, M.B., Schulze-Lefert, P., Ver Loren van Themaat, E., Ma, L.J. and Vaillancourt, L.J.
Nature Genetics 44
(9): 1060-5.
September 2012
Retinal damage in multiple sclerosis disease subtypes measured by high-resolution optical coherence tomography.
Oberwahrenbrock, T., Schippling, S., Ringelstein, M., Kaufhold, F., Zimmermann, H., Keser, N., Young, K.L., Harmel, J., Hartung, H.P., Martin, R., Paul, F., Aktas, O. and Brandt, A.U.
Multiple Sclerosis International 2012
: 530305.
25 July 2012
Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells.
Onal, P., Gruen, D., Adamidi, C., Rybak, A., Solana, J., Mastrobuoni, G., Wang, Y., Rahn, H.P., Chen, W., Kempa, S., Ziebold, U. and Rajewsky, N.
EMBO Journal 31
(12): 2755-2769.
27 April 2012
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction.
Orth, J.D., Loewer, A., Lahav, G. and Mitchison, T.J.
Molecular Biology of the Cell 23
(4): 567-576.
15 February 2012
Treatment of experimental brain metastasis with MTO-liposomes: impact of fluidity and LRP-targeting on the therapeutic result.
Orthmann, A., Zeisig, R., Suess, R., Lorenz, D., Lemm, M. and Fichtner, I.
Pharmaceutical Research 29
(7): 1949-1959.
July 2012
Xirp proteins mark injured skeletal muscle in zebrafish.
Otten, C., van der Ven, P.F., Lewrenz, I., Paul, S., Steinhagen, A., Busch-Nentwich, E., Eichhorst, J., Wiesner, B., Stemple, D., Straehle, U., Fuerst, D.O. and Abdelilah-Seyfried, S.
PLoS ONE 7
(2): e31041.
15 February 2012
Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cavβ(2).
Pankonien, I., Otto, A., Dascal, N., Morano, I. and Haase, H.
Biochemical and Biophysical Research Communications 421
(2): 184-189.
4 May 2012
Removal of polycomb repressive complex 2 makes C. elegans germ cells susceptible to direct conversion into specific somatic cell types.
Patel, T., Tursun, B., Rahe, D.P. and Hobert, O.
Cell Reports 2
(5): 1178-1186.
29 November 2012
Immunmodulatorische Therapie mit Interferon β-1b bei klinisch isoliertem Syndrom [Immunomodulatory therapy with interferon β-1b in clinically isolated syndrome.
Paul, F.
Aktuelle Neurologie 39
(S1): S16-S18.
22 May 2012
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.
Peifer, M., Fernández-Cuesta, L., Sos, M.L., George, J., Seidel, D., Kasper, L.H., Plenker, D., Leenders, F., Sun, R., Zander, T., Menon, R., Koker, M., Dahmen, I., Müller, C., Di Cerbo, V., Schildhaus, H.U., Altmüller, J., Baessmann, I., Becker, C., de Wilde, B., Vandesompele, J., Böhm, D., Ansén, S., Gabler, F., Wilkening, I., Heynck, S., Heuckmann, J.M., Lu, X., Carter, S.L., Cibulskis, K., Banerji, S., Getz, G., Park, K.S., Rauh, D., Grütter, C., Fischer, M., Pasqualucci, L., Wright, G., Wainer, Z., Russell, P., Petersen, I., Chen, Y., Stoelben, E., Ludwig, C., Schnabel, P., Hoffmann, H., Muley, T., Brockmann, M., Engel-Riedel, W., Muscarella, L.A., Fazio, V.M., Groen, H., Timens, W., Sietsma, H., Thunnissen, E., Smit, E., Heideman, D.A.M., Snijders, P.J.F., Cappuzzo, F., Ligorio, C., Damiani, S., Field, J., Solberg, S., Brustugun, O.T., Lund-Iversen, M., Sänger, J., Clement, J.H., Soltermann, A., Moch, H., Weder, W., Solomon, B., Soria, J.C., Validire, P., Besse, B., Brambilla, E., Brambilla, C., Lantuejoul, S., Lorimier, P., Schneider, P.M., Hallek, M., Pao, W., Meyerson, M., Sage, J., Shendure, J., Schneider, R., Büttner, R., Wolf, J., Nürnberg, P., Perner, S., Heukamp, L.C., Brindle, P.K., Haas, S. and Thomas, R.K.
Nature Genetics 44
(10): 1104-10.
October 2012
A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.
Peng, C., Li, N., Ng, Y.K., Zhang, J., Meier, F., Theis, F.J., Merkenschlager, M., Chen, W., Wurst, W. and Prakash, N.
Journal of Neuroscience 32
(38): 13292-13308.
19 September 2012
A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI.
Peters, O., Lorenz, D., Fesche, A., Schmidtke, K., Hull, M., Perneczky, R., Ruether, E., Moeller, H.J., Jessen, F., Maier, W., Kornhuber, J., Jahn, H., Luckhaus, C., Gertz, H.J., Schroeder, J., Pantel, J., Teipel, S., Wellek, S., Froelich, L. and Heuser, I.
Journal of Nutrition Health & Aging 16
(6): 544-548.
June 2012
Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.
Peterson, K.A., Nishi, Y., Ma, W., Vedenko, A., Shokri, L., Zhang, X., McFarlane, M., Baizabal, J.M., Junker, J.P., van Oudenaarden, A., Mikkelsen, T., Bernstein, B.E., Bailey, T.L., Bulyk, M.L., Wong, W.H. and McMahon, A.P.
Genes & Development 26
(24): 2802-2816.
15 December 2012
Gateway compatible transposon vector to genetically modify human embryonic kidney and adipose-derived stromal cells.
Petrakis, S., Rasko, T., Mates, L., Ivics, Z., Izsvak, Z., Kouzi-Koliakou, K. and Koliakos, G.
Biotechnology Journal 7
(7): 891-897.
July 2012
Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.
Petrakis, S., Rasko, T., Russ, J., Friedrich, R.P., Stroedicke, M., Riechers, S.P., Muehlenberg, K., Moeller, A., Reinhardt, A., Vinayagam, A., Schaefer, M.H., Boutros, M., Tricoire, H., Andrade-Navarro, M.A. and Wanker, E.E.
PLoS Genetics 8
(8): e1002897.
16 August 2012
The protein expression landscape of the Arabidopsis root.
Petricka, J.J., Schauer, M.A., Megraw, M., Breakfield, N.W., Thompson, J.W., Georgiev, S., Soderblom, E.J., Ohler, U., Moseley, M.A., Grossniklaus, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 109
(18): 6811-6818.
1 May 2012
A system for ex vivo culturing of embryonic pancreas.
Petzold, K.M. and Spagnoli, F.M.
Journal of Visualized Experiments
(66): e3979.
27 August 2012
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Phadwal, K., Alegre-Abarrategui, J., Watson, A.S., Pike, L., Anbalagan, S., Hammond, E.M., Wade-Martins, R., McMichael, A., Klenerman, P. and Simon, A.K.
Autophagy 8
(4): 677-89.
1 April 2012
Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.
Pham, T.H., Benner, C., Lichtinger, M., Schwarzfischer, L., Hu, Y., Andreesen, R., Chen, W. and Rehli, M.
Blood 119
(24): e161-e171.
14 June 2012
Dysferlin-deficient immortalized human myoblasts and myotubes as a useful tool to study dysferlinopathy.
Philippi, S., Bigot, A., Marg, A., Mouly, V., Spuler, S. and Zacharias, U.
PLoS Currents 4
: RRN1298.
28 February 2012
In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.
Pichorner, A., Sack, U., Kobelt, D., Kelch, I., Arlt, F., Smith, J., Walther, W., Schlag, P.M. and Stein, U.
Clinical and Experimental Metastasis 29
(6): 573-583.
August 2012
ImgLib2-generic image processing in Java.
Pietzsch, T., Preibisch, S., Tomancak, P. and Saalfeld, S.
Bioinformatics 28
(22): 3009-3011.
15 November 2012
ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia.
Pike, L.R.G., Phadwal, K., Simon, A.K. and Harris, A.L
Molecular Biology Reports 39
(12): 10811-22.
December 2012
Promoter architecture of mouse olfactory receptor genes.
Plessy, C., Pascarella, G., Bertin, N., Akalin, A., Carrieri, C., Vassalli, A., Lazarevic, D., Severin, J., Vlachouli, C., Simone, R., Faulkner, G.J., Kawai, J., Daub, C.O., Zucchelli, S., Hayashizaki, Y., Mombaerts, P., Lenhard, B., Gustincich, S. and Carninci, P.
Genome Research 22
(3): 486-497.
March 2012
Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells.
Ploetz, M., Gillissen, B., Hossini, A.M., Daniel, P.T. and Eberle, J.
Cell Death and Differentiation 19
(12): 1928-1938.
December 2012
Thalamic control of cortical states.
Poulet, J.F.A., Fernandez, L.M.J., Crochet, S. and Petersen, C.C.H.
Nature Neuroscience 15
(3): 370-372.
22 January 2012
eggNOG v3.0: orthologous groups covering 1133 organisms at 41 different taxonomic ranges.
Powell, S., Szklarczyk, D., Trachana, K., Roth, A., Kuhn, M., Muller, J., Arnold, R., Rattei, T., Letunic, I., Doerks, T., Jensen, L.J., von Mering, C. and Bork, P.
Nucleic Acids Research 40
(D1): D284-D289.
1 January 2012
The JAK2 variant rs10758669 in Crohn's disease: altering the intestinal barrier as one mechanism of action.
Prager, M., Buettner, J., Haas, V., Baumgart, D.C., Sturm, A., Zeitz, M. and Buening, C.
International Journal of Colorectal Disease 27
(5): 565-573.
May 2012
Mutations in RD3 are associated with an extremely rare and severe form of early onset retinal dystrophy.
Preising, M.N., Hausotter-Will, N., Solbach, M.C., Friedburg, C., Rueschendorf, F. and Lorenz, B.
Investigative Ophthalmology & Visual Science 53
(7): 3463-3472.
8 June 2012
IgA NMDA receptor antibodies are markers of synaptic immunity in slow cognitive impairment.
Pruess, H., Hoeltje, M., Maier, N., Gomez, A., Buchert, R., Harms, L., Ahnert-Hilger, G., Schmitz, D., Terborg, C., Kopp, U., Klingbeil, C., Probst, C., Kohler, S., Schwab, J.M., Stoecker, W., Dalmau, J. and Wandinger, K.P.
Neurology 78
(22): 1743-1753.
29 May 2012
The Pfam protein families database.
Punta, M., Coggill, P.C., Eberhardt, R.Y., Mistry, J., Tate, J., Boursnell, C., Pang, N., Forslund, K., Ceric, G., Clements, J., Heger, A., Holm, L., Sonnhammer, E.L.L., Eddy, S.R., Bateman, A. and Finn, R.D.
Nucleic Acids Research 40
(D1): D290-D301.
1 January 2012
p53 dynamics control cell fate.
Purvis, J.E., Karhohs, K.W., Mock, C., Batchelor, E., Loewer, A. and Lahav, G.
Science 336
(6087): 1440-1444.
15 June 2012
De la gestion a la logique de la complexite : genealogie d'une pratique epistemique [From the management to an analytics of complexity: genealogy of an epistemic practice].
Ramillon, V.
Medecine Sciences 28
(Hors serie n degrees 2): 34-38.
June 2012
Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking.
Renner, U., Zeug, A., Woehler, A., Niebert, M., Dityatev, A., Dityateva, G., Gorinski, N., Guseva, D., Abdel-Galil, D., Froehlich, M., Doering, F., Wischmeyer, E., Richter, D.W., Neher, E. and Ponimaskin, E.G.
Journal of Cell Science 125
(Pt 10): 2486-2499.
15 May 2012
Magnetic resonance elastography reveals altered brain viscoelasticity in experimental autoimmune encephalomyelitis.
Riek, K., Millward, J.M., Hamann, I., Mueller, S., Pfueller, C.F., Paul, F., Braun, J., Infante-Duarte, C. and Sack, I.
NeuroImage: Clinical 1
(1): 81-90.
12 November 2012
Where is the gap?
Riethmueller, S., Luft, F.C. and Mohebbi, N.
Clinical Kidney Journal 5
(1): 63-64.
February 2012
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.
Roberts, N.A., White, A.J., Jenkinson, W.E., Turchinovich, G., Nakamura, K., Withers, D.R., McConnell, F.M., Desanti, G.E., Benezech, C., Parnell, S.M., Cunningham, A.F., Paolino, M., Penninger, J.M., Simon, A.K., Nitta, T., Ohigashi, I., Takahama, Y., Caamano, J.H., Hayday, A.C., Lane, P.J.L., Jenkinson, E.J. and Anderson, G.
Immunity 36
(3): 427-37.
23 March 2012
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain.
Rogelj, B., Easton, L.E., Bogu, G.K., Stanton, L.W., Rot, G., Curk, T., Zupan, B., Sugimoto, Y., Modic, M., Haberman, N., Tollervey, J., Fujii, R., Takumi, T., Shaw, C.E. and Ule, J.
Scientific Reports 2
: 603.
28 August 2012
Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin.
Rosario, M., Schuster, S., Juettner, R., Parthasarathy, S., Tarabykin, V. and Birchmeier, W.
Genes & Development 26
(15): 1743-1757.
1 August 2012
Heterozygous de-novo mutations in ATP1A3 in patients with alternating hemiplegia of childhood: a whole-exome sequencing gene-identification study.
Rosewich, H., Thiele, H., Ohlenbusch, A., Maschke, U., Altmüller, J., Frommolt, P., Zirn, B., Ebinger, F., Siemes, H., Nürnberg, P., Brockmann, K. and Gärtner, J.
Lancet Neurology 11
(9): 764-73.
September 2012
Quantification of uncoupling protein 2 reveals its main expression in immune cells and selective up-regulation during T-cell proliferation.
Rupprecht, A., Braeuer, A.U., Smorodchenko, A., Goyn, J., Hilse, K.E., Shabalina, I.G., Infante-Duarte, C. and Pohl, E.E.
PLoS ONE 7
(8): e41406.
3 August 2012
RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.
Sachs, R., Max, K.E., Heinemann, U. and Balbach, J.
RNA 18
(1): 65-76.
January 2012
GluK1 inhibits calcium dependent and independent transmitter release at associational/commissural synapses in area CA3 of the hippocampus.
Salmen, B., Beed, P.S., Ozdogan, T., Maier, N., Johenning, F.W., Winterer, J., Breustedt, J. and Schmitz, D.
Hippocampus 22
(1): 57-68.
January 2012
Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.
Sander, S., Calado, D.P., Srinivasan, L., Köchert, K., Zhang, B., Rosolowski, M., Rodig, S.J., Holzmann, K., Stilgenbauer, S., Siebert, R., Bullinger, L. and Rajewsky, K.
Cancer Cell 22
(2): 167-179.
14 August 2012
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.
Sankaran, V.G., Ludwig, L.S., Sicinska, E., Xu, J., Bauer, D.E., Eng, J.C., Patterson, H.C., Metcalf, R.A., Natkunam, Y., Orkin, S.H., Sicinski, P., Lander, E.S. and Lodish, H.F.
Genes & Development 26
(18): 2075-2087.
15 September 2012
Detailing radio frequency heating induced by coronary stents: a 7.0 tesla magnetic resonance study.
Santoro, D., Winter, L., Mueller, A., Vogt, J., Renz, W., Ozerdem, C., Graessl, A., Tkachenko, V., Schulz-Menger, J. and Niendorf, T.
PLoS ONE 7
(11): e49963.
21 November 2012
Increased circulating angiotensin-(1-7) protects white adipose tissue against development of a proinflammatory state stimulated by high-fat diet.
Santos, S.H.S., Rodrigues Fernandes, L., Santos Pereira, C., Senna Guimaraes, A.L., de Paula, A.M.B., Campagnole-Santos, M.J., Alvarez-Leite, J.I., Bader, M. and Santos, R.A.S.
Regulatory Peptides 178
(1-3): 64-70.
10 October 2012
HIPPIE: integrating protein interaction networks with experiment based quality scores.
Schaefer, M.H., Fontaine, J.F., Vinayagam, A., Porras, P., Wanker, E.E. and Andrade-Navarro, M.A.
PLoS ONE 7
(2): e31826.
14 February 2012
Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.
Schaefer, M.H., Wanker, E.E. and Andrade-Navarro, M.A.
Nucleic Acids Research 40
(10): 4273-4287.
1 May 2012
Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia.
Scheffel, J., Regen, T., Van Rossum, D., Seifert, S., Ribes, S., Nau, R., Parsa, R., Harris, R.A., Boddeke, H.W.G.M., Chuang, H.N., Pukrop, T., Wessels, J.T., Juergens, T., Merkler, D., Brueck, W., Schnaars, M., Simons, M., Kettenmann, H. and Hanisch, U.K.
Glia 60
(12): 1930-1943.
December 2012
Targeted tumor therapy with a fusion Protein of an antiangiogenic human recombinant scFv and yeast cytosine deaminase.
Schellmann, N., Panjideh, H., Fasold, P., Bachran, D., Bachran, C., Deckert, P.M. and Fuchs, H.
Journal of Immunotherapy 35
(7): 570-578.
September 2012
How does the ryanodine receptor in the ventricular myocyte wake up: by a single or by multiple open L-type Ca(2+) channels?
Schendel, T., Thul, R., Sneyd, J. and Falcke, M.
European Biophysics Journal 41
(1): 27-39.
January 2012
Statins and the elderly: recent evidence and current indications.
Schiattarella, G.G., Perrino, C., Magliulo, F., Ilardi, F., Serino, F., Trimarco, V., Izzo, R., Amato, B., Terranova, C., Cardin, F., Militello, C., Leosco, D., Trimarco, B. and Esposito, G.
Aging Clinical and Experimental Research 24
(Suppl 3): 47-55.
June 2012
Fiji: an open-source platform for biological-image analysis.
Schindelin, J., Arganda-Carreras, I., Frise, E., Kaynig, V., Longair, M., Pietzsch, T., Preibisch, S., Rueden, C., Saalfeld, S., Schmid, B., Tinevez, J.Y., White, D.J., Hartenstein, V., Eliceiri, K., Tomancak, P. and Cardona, A.
Nature Methods 9
(7): 676-682.
July 2012
Efficacy of vision restoration therapy after optic neuritis (VISION study): study protocol for a randomized controlled trial.
Schinzel, J., Schwarzlose, L., Dietze, H., Bartusch, K., Weiss, S., Ohlraun, S., Paul, F. and Doerr, J.
Trials 13
: 94.
28 June 2012
Impact of beta-amyloid-specific florbetaben PET imaging on confidence in early diagnosis of Alzheimer's disease.
Schipke, C.G., Peters, O., Heuser, I., Grimmer, T., Sabbagh, M.N., Sabri, O., Hock, C., Kunz, M., Kuhlmann, J., Reininger, C. and Blankenburg, M.
Dementia and Geriatric Cognitive Disorders 33
(6): 416-422.
August 2012
The inhibition of the integrin VLA-4 in MV3 melanoma cell binding by non-anticoagulant heparin derivatives.
Schlesinger, M., Schmitz, P., Zeisig, R., Naggi, A., Torri, G., Casu, B. and Bendas, G.
Thrombosis Research 129
(5): 603-610.
May 2012
Peptide linkage to the α-subunit of MHCII creates a stably inverted antigen presentation complex.
Schlundt, A., Guenther, S., Sticht, J., Wieczorek, M., Roske, Y., Heinemann, U. and Freund, C.
Journal of Molecular Biology 423
(3): 294-302.
26 October 2012
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
Schmeisser, M.J., Ey, E., Wegener, S., Bockmann, J., Stempel, A.V., Kuebler, A., Janssen, A.L., Udvardi, P.T., Shiban, E., Spilker, C., Balschun, D., Skryabin, B.V., Dieck, S.t., Smalla, K.H., Montag, D., Leblond, C.S., Faure, P., Torquet, N., Le Sourd, A.M., Toro, R., Grabrucker, A.M., Shoichet, S.A., Schmitz, D., Kreutz, M.R., Bourgeron, T., Gundelfinger, E.D. and Boeckers, T.M.
Nature 486
(7402): 256-260.
29 April 2012
Sex differences in the drug therapy for oncologic diseases.
Schmetzer, O. and Floercken, A.
Handbook of Experimental Pharmacology 214
(3): 411-442.
2012
Detection of circulating tumor-associated antigen depends on the domains recognized by the monoclonal antibodies used: N-terminal trimmed EpCAM-levels are much higher than untrimmed forms.
Schmetzer, O., Moldenhauer, G., Nicolaou, A., Schlag, P., Riesenberg, R. and Pezzutto, A.
Immunology Letters 143
(2): 184-192.
30 April 2012
SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer.
Schmid, F., Burock, S., Klockmeier, K., Schlag, P.M. and Stein, U.
Molecular Cancer 11
(1): 49.
29 July 2012
Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease.
Schmidt, V., Baum, K., Lao, A., Rateitschak, K., Schmitz, Y., Teichmann, A., Wiesner, B., Petersen, C.M., Nykjaer, A., Wolf, J., Wolkenhauer, O. and Willnow, T.E.
EMBO Journal 31
(1): 187-200.
4 January 2012
Dysferlin-peptides reallocate mutated dysferlin thereby restoring function.
Schoewel, V., Marg, A., Kunz, S., Overkamp, T., Siegert Carrazedo, R., Zacharias, U., Daniel, P.T. and Spuler, S.
PLoS ONE 7
(11): e49603.
20 November 2012
ANCA-assoziierte Vaskulitiden: Neuere Aspekte der Entstehung [Antineutrophil cytoplasmic antibody-associated vasculitis: novel aspects in the pathogenesis].
Schreiber, A., Choi, M. and Kettritz, R.
Nephrologe 7
(3): 192-199.
May 2012
Neutrophil serine proteases promote IL-1beta generation and injury in necrotizing crescentic glomerulonephritis.
Schreiber, A., Pham, C.T., Hu, Y., Schneider, W., Luft, F.C. and Kettritz, R.
Journal of the American Society of Nephrology 23
(3): 470-482.
March 2012
Genes involved in the metastatic cascade of medullary thyroid tumours.
Schreiber, C., Vormbrock, K. and Ziebold, U.
Methods in Molecular Biology 878
: 217-228.
2012
Genome-wide association study of vascular dementia.
Schrijvers, E.M., Schuermann, B., Koudstaal, P.J., van den Bussche, H., Van Duijn, C.M., Hentschel, F., Heun, R., Hofman, A., Jessen, F., Koelsch, H., Kornhuber, J., Peters, O., Rivadeneira, F., Ruether, E., Uitterlinden, A.G., Riedel-Heller, S., Dichgans, M., Wiltfang, J., Maier, W., Breteler, M.M.B. and Ikram, M.A.
Stroke 43
(2): 315-319.
February 2012
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.
Schroder, K., Irvine, K.M., Taylor, M.S., Bokil, N.J., Le Cao, K.A., Masterman, K.A., Labzin, L.I., Semple, C.A., Kapetanovic, R., Fairbairn, L., Akalin, A., Faulkner, G.J., Baillie, J.K., Gongora, M., Daub, C.O., Kawaji, H., McLachlan, G.J., Goldman, N., Grimmond, S.M., Carninci, P., Suzuki, H., Hayashizaki, Y., Lenhard, B., Hume, D.A. and Sweet, M.J.
Proceedings of the National Academy of Sciences of the United States of America 109
(16): E944-E953.
17 April 2012
Dynamics of Srf, p300 and histone modifications during cardiac maturation in mouse.
Schueler, M., Zhang, Q., Schlesinger, J., Toenjes, M. and Sperling, S.R.
Molecular BioSystems 8
(2): 495-503.
February 2012
MWF rats with spontaneous albuminuria inherit a reduced efficiency of nephron induction during early nephrogenesis in comparison to SHRs.
Schulte, L., Schulz, A., Unland, J., Schulz, H., Hubner, N., Schmidt-Ott, K.M. and Kreutz, R.
Journal of Hypertension 30
(10): 2031-2038.
October 2012
Aortic valve replacement in asymptomatic and symptomatic patients with preserved left ventricular ejection fraction.
Schulz, O., Brala, D., Bensch, R., Kraemer, J., Schulz-Menger, J., Berghoefer, G. and Schimke, I.
Journal of Heart Valve Disease 21
(5): 576-583.
September 2012
CCR7 deficiency causes diarrhea associated with altered ion transport in colonocytes in the absence of overt colitis.
Schumann, M., Winter, S., Wichner, K., May, C., Kuehl, A.A., Batra, A., Siegmund, B., Zeitz, M., Schulzke, J.D., Lipp, M. and Höpken, U.E.
Mucosal Immunology 5
(4): 377-387.
July 2012
Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells.
Schwarzer, R., Doerken, B. and Jundt, F.
Leukemia 26
(4): 806-813.
April 2012
Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses.
Schöbel, Ni., Radtke, D., Lübbert, M., Gisselmann, G., Lehmann, R., Cichy, A., Schreiner, B.S.P., Altmüller, J., Spector, A.C., Spehr, J., Hatt, H. and Wetzel, C.H.
PLoS ONE 7
(11): e48005.
8 November 2012
Raising cytosolic Cl(-) in cerebellar granule cells affects their excitability and vestibulo-ocular learning.
Seja, P., Schonewille, M., Spitzmaul, G., Badura, A., Klein, I., Rudhard, Y., Wisden, W., Huebner, C.A., De Zeeuw, C.I. and Jentsch, T.J.
EMBO Journal 31
(5): 1217-1230.
17 January 2012
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity.
Seymour, P.A., Shih, H.P., Patel, N.A., Freude, K.K., Xie, R., Lim, C.J. and Sander, M.
Development 139
(18): 3363-72.
September 2012
Elucidating membrane structure and protein behavior using giant plasma membrane vesicles.
Sezgin, E., Kaiser, H.J., Baumgart, T., Schwille, P., Simons, K. and Levental, I.
Nature Protocols 7
(6): 1042-1051.
June 2012
The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation.
Shabek, N., Herman-Bachinsky, Y., Buchsbaum, S., Lewinson, O., Haj-Yahya, M., Hejjaoui, M., Lashuel, H.A., Sommer, T., Brik, A. and Ciechanover, A.
Molecular Cell 48
(1): 87-97.
12 October 2012
The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Shah, S.P., Roth, A., Goya, R., Oloumi, A., Ha, G., Zhao, Y., Turashvili, G., Ding, J., Tse, K., Haffari, G., Bashashati, A., Prentice, L.M., Khattra, J., Burleigh, A., Yap, D., Bernard, V., McPherson, A., Shumansky, K., Crisan, A., Giuliany, R., Heravi-Moussavi, A., Rosner, J., Lai, D., Birol, I., Varhol, R., Tam, A., Dhalla, N., Zeng, T., Ma, K., Chan, S.K., Griffith, M., Moradian, A., Cheng, S.W.G., Morin, G.B., Watson, P., Gelmon, K., Chia, S., Chin, S.F., Curtis, C., Rueda, O.M., Pharoah, P.D., Damaraju, S., Mackey, J., Hoon, K., Harkins, T., Tadigotla, V., Sigaroudinia, M., Gascard, P., Tlsty, T., Costello, J.F., Meyer, I.M., Eaves, C.J., Wasserman, W.W., Jones, S., Huntsman, D., Hirst, M., Caldas, C., Marra, M.A. and Aparicio, S.
Nature 486
(7403): 395-399.
21 June 2012
Interleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis.
Shalapour, S., Deiser, K., Kuehl, A.A., Glauben, R., Krug, S.M., Fischer, A., Sercan, O., Chappaz, S., Bereswill, S., Heimesaat, M.M., Loddenkemper, C., Fromm, M., Finke, D., Haemmerling, G.J., Arnold, B., Siegmund, B. and Schueler, T.
PLoS ONE 7
(2): e31939.
27 February 2012
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
Shih, H.P., Kopp, J.L., Sandhu, M., Dubois, C.L., Seymour, P.A., Grapin-Botton, A. and Sander, M.
Development 139
(14): 2488-99.
July 2012
An image-based biosensor assay strategy to screen for modulators of the microRNA 21 biogenesis pathway.
Shum, D., Bhinder, B., Radu, C., Farazi, T., Landthaler, M., Tuschl, T., Calder, P., Ramirez, C.N. and Djaballah, H.
Combinatorial Chemistry & High Throughput Screening 15
(7): 529-541.
August 2012
Neuroendokrine Neoplasien des gastroenteropankreatischen Systems [Gastroenteropancreatic neuro-endocrine neoplasms].
Sigal, M., Pape, F. and Wiedenmann, B.
Therapeutische Umschau 69
(10): 591-596.
October 2012
A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis.
Simon, R., Brylka, H., Schwegler, H., Venkataramanappa, S., Andratschke, J., Wiegreffe, C., Liu, P., Fuchs, E., Jenkins, N.A., Copeland, N.G., Birchmeier, C. and Britsch, S.
EMBO Journal 31
(13): 2922-2936.
15 May 2012
Divergent gene expression in the conserved dauer stage of the nematodes Pristionchus pacificus and Caenorhabditis elegans.
Sinha, A., Sommer, R.J. and Dieterich, C.
BMC Genomics 13
(1): 254.
19 June 2012
Morphology and ultrastructure of the chorioallantoic placenta of the Iberian mole (Talpa occidentalis) with special reference to heterophagous areolas and the nature of interhaemal barrier.
Siniza, S., Lupianez, D.G., Jimenez, R. and Zeller, U.
Journal of Anatomy 221
(2): 164-173.
August 2012
Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis.
Sinnecker, T., Doerr, J., Pfueller, C.F., Harms, L., Ruprecht, K., Jarius, S., Brueck, W., Niendorf, T., Wuerfel, J. and Paul, F.
Neurology 79
(7): 708-714.
14 August 2012
Multiple sclerosis lesions and irreversible brain tissue damage: a comparative ultrahigh-field strength magnetic resonance imaging study.
Sinnecker, T., Mittelstaedt, P., Doerr, J., Pfueller, C.F., Harms, L., Niendorf, T., Paul, F. and Wuerfel, J.
Archives of Neurology 69
(6): 739-745.
June 2012
The viral and cellular microRNA targetome in lymphoblastoid cell lines.
Skalsky, R.L., Corcoran, D.L., Gottwein, E., Frank, C.L., Kang, D., Hafner, M., Nusbaum, J.D., Feederle, R., Delecluse, H.J., Luftig, M.A., Tuschl, T., Ohler, U. and Cullen, B.R.
PLoS Pathogens 8
(1): e1002484.
26 January 2012
Calcium signaling: from single channels to pathways.
Skupin, A. and Thurley, K.
Advances in Experimental Medicine and Biology 740
: 531-551.
2012
Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis.
Smink, J.J., Tunn, P.U. and Leutz, A.
Journal of Molecular Medicine 90
(1): 25-30.
January 2012
Specific paucity of unmyelinated C-fibers in cutaneous peripheral nerves of the African naked-mole rat: comparative analysis using six species of bathyergidae.
Smith, E.S.J., Purfürst, B., Grigoryan, T., Park, T.J., Bennett, N.C. and Lewin, G.R.
Journal of Comparative Neurology 520
(12): 2785-2803.
15 August 2012
High prevalence and breast cancer predisposing role of the BLMc.1642 C>T (Q548X) mutation in Russia.
Sokolenko, A.P., Iyevleva, A.G., Preobrazhenskaya, E.V., Mitiushkina, N.V., Abysheva, S.N., Suspitsin, E.N., Kuligina, E.S., Gorodnova, T.V., Pfeifer, W., Togo, A.V., Turkevich, E.A., Ivantsov, A.O., Voskresenskiy, D.V., Dolmatov, G.D., Bit-Sava, E.M., Matsko, D.E., Semiglazov, V.F., Fichtner, I., Larionov, A.A., Kuznetsov, S.G., Antoniou, A.C. and Imyanitov, E.N.
International Journal of Cancer 130
(12): 2867-2873.
15 June 2012
Caipirini: using gene sets to rank literature.
Soldatos, T.G., O'Donoghue, S.I., Satagopam, V.P., Barbosa-Silva, A., Pavlopoulos, G.A., Wanderley-Nogueira, A.C., Soares-Cavalcanti, N.M. and Schneider, R.
BioData Mining 5
(1): 1.
1 February 2012
670 nm laser light and EGCG complementarily reduce amyloid-β aggregates in human neuroblastoma cells: basis for treatment of Alzheimer's disease?
Sommer, A.P., Bieschke, J., Friedrich, R.P., Zhu, D., Wanker, E.E., Fecht, H.J., Mereles, D. and Hunstein, W.
Photomedicine and Laser Surgery 30
(1): 54-60.
4 January 2012
Select microRNAs are essential for early development in the sea urchin.
Song, J.L., Stoeckius, M., Maaskola, J., Friedlaender, M., Stepicheva, N., Juliano, C., Lebedeva, S., Thompson, W., Rajewsky, N. and Wessel, G.M.
Developmental Biology 362
(1): 104-113.
1 February 2012
Predictive factors for the benefit of perioperative FOLFOX for resectable liver metastasis in colorectal cancer patients (EORTC Intergroup trial 40983).
Sorbye, H., Mauer, M., Gruenberger, T., Glimelius, B., Poston, G.J., Schlag, P.M., Rougier, P., Bechstein, W.O., Primrose, J.N., Walpole, E.T., Finch-Jones, M., Jaeck, D., Mirza, D., Parks, R.W., Collette, L., Cutsem, E.V., Scheithauer, W., Lutz, M.P. and Nordlinger, B.
Annals of Surgery 255
(3): 534-539.
March 2012
TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.
Spranger, S., Jeremias, I., Wilde, S., Leisegang, M., Staerck, L., Mosetter, B., Uckert, W., Heemskerk, M.H.M., Schendel, D.J. and Frankenberger, B.
Blood 119
(15): 3440-3449.
12 April 2012
Cell biology and physiology of CLC chloride channels and transporters.
Stauber, T., Weinert, S. and Jentsch, T.J.
Comprehensive Physiology 2
(3): 1701-1744.
1 July 2012
Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.
Steffens, M., Leu, C., Ruppert, A.K., Zara, F., Striano, P., Robbiano, A., Capovilla, G., Tinuper, P., Gambardella, A., Bianchi, A., La Neve, A., Crichiutti, G., de Kovel, C.G.F., Kasteleijn-Nolst Trenite, D., de Haan, G.J., Lindhout, D., Gaus, V., Schmitz, B., Janz, D., Weber, Y.G., Becker, F., Lerche, H., Steinhoff, B.J., Kleefuss-Lie, A.A., Kunz, W.S., Surges, R., Elger, C.E., Muhle, H., von Spiczak, S., Ostertag, P., Helbig, I., Stephani, U., Moller, R.S., Hjalgrim, H., Dibbens, L.M., Bellows, S., Oliver, K., Mullen, S., Scheffer, I.E., Berkovic, S.F., Everett, K.V., Gardiner, M.R., Marini, C., Guerrini, R., Lehesjoki, A.E., Siren, A., Guipponi, M., Malafosse, A., Thomas, P., Nabbout, R., Baulac, S., Leguern, E., Guerrero, R., Serratosa, J.M., Reif, P.S., Rosenow, F., Mörzinger, M., Feucht, M., Zimprich, F., Kapser, C., Schankin, C.J., Suls, A., Smets, K., De Jonghe, P., Jordanova, A., Caglayan, H., Yapici, Z., Yalcin, D.A., Baykan, B., Bebek, N., Ozbek, U., Gieger, C., Wichmann, H.E., Balschun, T., Ellinghaus, D., Franke, A., Meesters, C., Becker, T, Wienker, T.F., Hempelmann, A., Schulz, H., Rueschendorf, F., Leber, M., Pauck, S.M., Trucks, H., Toliat, M.R., Nuernberg, P., Avanzini, G., Koeleman, B.P. and Sander, T.
Human Molecular Genetics 21
(24): 5359-5372.
15 December 2012
The hok mRNA family.
Steif, A. and Meyer, I.M.
RNA Biology 9
(12): 1399-1404.
1 December 2012
Circulating MACC1 transcripts in colorectal cancer patient plasma predict metastasis and prognosis.
Stein, U., Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Schlag, P.M.
PLoS ONE 7
(11): e49249.
14 November 2012
Impact of mutant beta-catenin on ABCB1 expression and therapy response in colon cancer cells.
Stein, U., Fleuter, C., Siegel, F., Smith, J., Kopacek, A., Scudiero, D.A., Hite, K.M., Schlag, P.M., Shoemaker, R.H. and Walther, W.
British Journal of Cancer 106
(8): 1395-1405.
10 April 2012
Physical activity and risk of type 2 Diabetes among native Hawaiians, Japanese Americans, and Caucasians: the multiethnic cohort.
Steinbrecher, A., Erber, E., Grandinetti, A., Nigg, C., Kolonel, L.N. and Maskarinec, G.
Journal of Physical Activity & Health 9
(5): 634-641.
July 2012
Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1.
Stock, K., Kumar, J., Synowitz, M., Petrosino, S., Imperatore, R., Smith, E.S.J., Wend, P., Purfürst, B., Nuber, U.A., Gurok, U., Matyash, V., Waelzlein, J.H., Chirasani, S.R., Dittmar, G., Cravatt, B.F., Momma, S., Lewin, G.R., Ligresti, A., De Petrocellis, L., Cristino, L., Di Marzo, V., Kettenmann, H. and Glass, R.
Nature Medicine 18
(8): 1232-1238.
August 2012
Brain viscoelasticity alteration in chronic-progressive multiple sclerosis.
Streitberger, K.J., Sack, I., Krefting, D., Pfueller, C., Braun, J., Paul, F. and Wuerfel, J.
PLoS ONE 7
(1): e29888.
20 January 2012
Incidence of therapy-related acute leukaemia in mitoxantrone-treated multiple sclerosis patients in Germany.
Stroet, A., Hemmelmann, C., Starck, M., Zettl, U., Doerr, J., Paul, F., Flachenecker, P., Fleischer, V., Zipp, F., Nueckel, H., Kieseier, B.C., Ziegler, A., Gold, R. and Chan, A.
Therapeutic Advances in Neurological Disorders 5
(2): 75-79.
March 2012
Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions.
Sugimoto, Y., König, J., Hussain, S., Zupan, B., Curk, T., Frye, M. and Ule, J.
Genome Biology 13
(8): R67.
3 August 2012
Cardiovascular biomarker midregional proatrial natriuretic peptide during and after preeclamptic pregnancies.
Sugulle, M., Herse, F., Hering, L., Mockel, M., Dechend, R. and Staff, A.C.
Hypertension 59
(2): 395-401.
February 2012
Cardiovascular risk markers in pregnancies complicated by diabetes mellitus or preeclampsia.
Sugulle, M., Herse, F., Seiler, M., Dechend, R. and Staff, A.C.
Pregnancy Hypertension 2
(4): 403-410.
October 2012
Mean expression of the X-chromosome is associated with neuronal density.
Swingland, J.T., Durrenberger, P.F., Reynolds, R., Dexter, D.T., Pombo, A., Deprez, M., Roncaroli, F. and Turkheimer, F.E.
Frontiers in Neuroscience 6
: 161.
12 November 2012
Die Abteilung fuer Tumorforschung und Experimentelle Pathologie des Gehirns am Kaiser-Wilhelm-Institut fuer Hirnforschung (KWIH) in Berlin-Buch (1937-1945) [Wilhelm Toennis and his Research Department at the Kaiser-Wilhelm Institute for Brain Research in Berlin-Buch (1937-1945)].
Synowitz, H.J., Collmann, H. and Rosenow, D.E.
Schriftenreihe der Deutschen Gesellschaft fuer Geschichte der Nervenheilkunde 18
: 431-462.
2012
Small molecule screening in zebrafish: swimming in potential drug therapies.
Tamplin, O.J., White, R.M., Jing, L., Kaufman, C.K., Lacadie, S.A., Li, P., Taylor, A.M. and Zon, L.I.
Wiley Interdisciplinary Reviews: Developmental Biology 1
(3): 459-468.
May 2012
Gα(q/11) signaling tonically modulates nociceptor function and contributes to activity-dependent sensitization.
Tappe-Theodor, A., Constantin, C.E., Tegeder, I., Lechner, S.G., Langeslag, M., Lepcynzsky, P., Wirotanseng, R.I., Kurejova, M., Agarwal, N., Nagy, G., Todd, A., Wettschureck, N., Offermanns, S., Kress, M., Lewin, G.R. and Kuner, R.
Pain 153
(1): 184-196.
January 2012
Live cell imaging of G protein-coupled receptors.
Teichmann, A., Schmidt, A., Wiesner, B., Oksche, A. and Schuelein, R.
Methods in Molecular Biology 897
: 139-169.
2012
Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.
Tewari, A.K., Yardimci, G.G., Shibata, Y., Sheffield, N.C., Song, L., Taylor, B.S., Georgiev, S.G., Coetzee, GA., Ohler, U., Furey, T.S., Crawford, G.E. and Febbo, P.G.
Genome Biology 13
(10): R88.
3 October 2012
Two-Dimensional sixteen channel transmit/receive coil array for cardiac MRI at 7.0 T: Design, evaluation, and application.
Thalhammer, C., Renz, W., Winter, L., Hezel, F., Rieger, J., Pfeiffer, H., Graessl, A., Seifert, F., Hoffmann, W., von Knobelsdorff-Brenkenhoff, F., Tkachenko, V., Schulz-Menger, J., Kellman, P. and Niendorf, T.
Journal of Magnetic Resonance Imaging 36
(4): 847-857.
October 2012
VEGF regulates TRPC6 channels in podocytes.
Thilo, F., Liu, Y., Loddenkemper, C., Schuelein, R., Schmidt, A., Yan, Z., Zhu, Z., Zakrzewicz, A., Gollasch, M. and Tepel, M.
Nephrology Dialysis Transplantation 27
(3): 921-929.
March 2012
Poly(ethylene glycol)-lipid-conjugated antibodies enhance dendritic cell phagocytosis of apoptotic cancer cells.
Tomita, U., Yamaguchi, S., Sugimoto, Y., Takamori, S. and Nagamune, T.
Pharmaceuticals 5
(5): 405-416.
26 April 2012
Axonal properties determine somatic firing in a model of in vitro CA1 hippocampal sharp wave/ripples and persistent gamma oscillations.
Traub, R.D., Schmitz, D., Maier, N., Whittington, M.A. and Draguhn, A.
European Journal of Neuroscience 36
(5): 2650-2660.
September 2012
Panglial gap junctional communication is essential for maintenance of myelin in the CNS.
Tress, O., Maglione, M., May, D., Pivneva, T., Richter, N., Seyfarth, J., Binder, S., Zlomuzica, A., Seifert, G., Theis, M., Dere, E., Kettenmann, H. and Willecke, K.
Journal of Neuroscience 32
(22): 7499-7518.
30 May 2012
Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus.
Trimpert, C., van den Berg, D.T.M., Fenton, R.A., Klussmann, E. and Deen, P.M.T.
Nephrology Dialysis Transplantation 27
(12): 4389-4397.
December 2012
The immune response to melanoma is limited by thymic selection of self-antigens.
Träger, U., Sierro, S., Djordjevic, G., Bouzo, B., Khandwala, S., Meloni, A., Mortensen, M. and Simon, A.K.
PLoS ONE 7
(4): e35005.
10 April 2012
A novel treatment strategy for sepsis and septic shock based on the interactions between prostanoids, nitric oxide, and 20-hydroxyeicosatetraenoic acid.
Tunctan, B., Korkmaz, B., Sari, A.N., Kacan, M., Unsal, D., Serin, M.S., Buharalioglu, C.K., Sahan-Firat, S., Schunck, W.H., Falck, J.R. and Malik, K.U.
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 11
(2): 121-150.
2012
Cellular reprogramming processes in Drosophila and C. elegans.
Tursun, B.
Current Opinion in Genetics & Development 22
(5): 475-484.
October 2012
Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
Udeshi, N.D., Mani, D.R., Eisenhaure, T., Mertins, P., Jaffe, J.D., Clauser, K.R., Hacohen, N. and Carr, S.A.
Molecular & Cellular Proteomics 11
(5): 148-159.
1 May 2012
Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.
Vaeth, M., Schliesser, U., Mueller, G., Reissig, S., Satoh, K., Tuettenberg, A., Jonuleit, H., Waisman, A., Mueller, M.R., Serfling, E., Sawitzki, B.S. and Berberich-Siebelt, F.
Proceedings of the National Academy of Sciences of the United States of America 109
(40): 16258-16263.
2 October 2012
Heterocyclic aromatic amine [HCA] intake and prostate cancer risk: effect modification by genetic variants.
Van Hemelrijck, M., Rohrmann, S., Steinbrecher, A., Kaaks, R., Teucher, B. and Linseisen, J.
Nutrition and Cancer 64
(5): 704-713.
July 2012
Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting.
Vogt, J., Glumm, R., Schlueter, L., Schmitz, D., Rost, B.R., Streu, N., Rister, B., Suman Bharathi, B., Gagiannis, D., Hildebrandt, H., Weinhold, B., Muehlenhoff, M., Naumann, T., Savaskan, N.E., Brauer, A.U., Reutter, W., Heimrich, B., Nitsch, R. and Horstkorte, R.
Cellular and Molecular Life Sciences 69
(7): 1179-1191.
April 2012
Retargeting Sleeping Beauty transposon insertions by engineered zinc finger DNA-binding domains.
Voigt, K., Gogol-Doering, A., Miskey, C., Chen, W., Cathomen, T., Izsvak, Z. and Ivics, Z.
Molecular Therapy 20
(10): 1852-1862.
October 2012
NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes.
Volcic, M., Karl, S., Baumann, B., Salles, D., Daniel, P., Fulda, S. and Wiesmueller, L.
Nucleic Acids Research 40
(1): 181-195.
January 2012
Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
Volz, T., Luetgehetmann, M., Allweiss, L., Warlich, M., Bierwolf, J., Pollok, J.M., Petersen, J., Matthes, E. and Dandri, M.
Antiviral Therapy 17
(4): 623-631.
27 February 2012
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline.
Vom Berg, J., Prokop, S., Miller, K.R., Obst, J., Kaelin, R.E., Lopategui-Cabezas, I., Wegner, A., Mair, F., Schipke, C.G., Peters, O., Winter, Y., Becher, B. and Heppner, F.L.
Nature Medicine 18
(12): 1812-1819.
December 2012
Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
Voutilainen, M., Lindfors, P.H., Lefebvre, S., Ahtiainen, L., Fliniaux, I., Rysti, E., Murtoniemi, M., Schneider, P., Schmidt-Ullrich, R. and Mikkola, M.L.
Proceedings of the National Academy of Sciences of the United States of America 109
(15): 5744-5749.
10 April 2012
Functional and morphological cardiac magnetic resonance imaging of mice using a cryogenic quadrature radiofrequency coil.
Wagenhaus, B., Pohlmann, A., Dieringer, M.A., Els, A., Waiczies, H., Waiczies, S., Schulz-Menger, J. and Niendorf, T.
PLoS ONE 7
(8): e42383.
1 August 2012
Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease.
Wagner, M., Wolf, S., Reischies, F.M., Daerr, M., Wolfsgruber, S., Jessen, F., Popp, J., Maier, W., Huell, M., Froelich, L., Hampel, H., Perneczky, R., Peters, O., Jahn, H., Luckhaus, C., Gertz, H.J., Schroeder, J., Pantel, J., Lewczuk, P., Kornhuber, J. and Wiltfang, J.
Neurology 78
(6): 379-386.
7 February 2012
Identification of cellular infiltrates during early stages of brain inflammation with magnetic resonance microscopy.
Waiczies, H., Millward, J.M., Lepore, S., Infante-Duarte, C., Pohlmann, A., Niendorf, T. and Waiczies, S.
PLoS ONE 7
(3): e32796.
12 March 2012
The first aptamer-apheresis column specifically for clearing blood of beta1-receptor autoantibodies : a successful proof of principle using autoantibody-positive SHR rats.
Wallukat, G., Haberland, A., Berg, S., Schulz, A., Freyse, E.J., Dahmen, C., Kage, A., Dandel, M., Vetter, R., Salzsieder, E., Kreutz, R. and Schimke, I.
Circulation Journal 76
(10): 2449-2455.
25 September 2012
Expression of coagulation factors and their receptors in tumor tissue and coagulation factor upregulation in peripheral blood of patients with cerebral carcinoma metastases.
Walter, J., Handel, L.L., Brodhun, M., van Rossum, D., Hanisch, U.K., Liebmann, L., Heppner, F., Goldbrunner, R., Koch, A. and Kuhn, S.A.
Journal of cancer research and clinical oncology 138
(1): 141-151.
January 2012
Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors.
Walther, W., Petkov, S., Kuvardina, O.N., Aumann, J., Kobelt, D., Fichtner, I., Lemm, M., Piontek, J., Blasig, I.E., Stein, U. and Schlag, P.M.
Gene Therapy 19
(5): 494-503.
May 2012
In-vivo tumor imaging using a novel RNAi-based detection mechanism.
Wan, K., Ebert, B., Voigt, J., Wang, Q., Dai, Y., Haag, R. and Kemmner, W.
Nanomedicine 8
(4): 393-398.
May 2012
Novel biomarkers for pre-diabetes identified by metabolomics.
Wang-Sattler, R., Yu, Z., Herder, C., Messias, A.C., Floegel, A., He, Y., Heim, K., Campillos, M., Holzapfel, C., Thorand, B., Grallert, H., Xu, T., Bader, E., Huth, C., Mittelstrass, K., Doering, A., Meisinger, C., Gieger, C., Prehn, C., Roemisch-Margl, W., Carstensen, M., Xie, L., Yamanaka-Okumura, H., Xing, G., Ceglarek, U., Thiery, J., Giani, G., Lickert, H., Lin, X., Li, Y., Boeing, H., Joost, H.G., de Angelis, M.H., Rathmann, W., Suhre, K., Prokisch, H., Peters, A., Meitinger, T., Roden, M., Wichmann, H.E., Pischon, T., Adamski, J. and Illig, T.
Molecular Systems Biology 8
: 615.
25 September 2012
Identification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-AT1, non-AT2 angiotensin binding site.
Wangler, N.J., Santos, K.L., Schadock, I., Hagen, F.K., Escher, E., Bader, M., Speth, R.C. and Karamyan, V.T.
Journal of Biological Chemistry 287
(1): 114-122.
2 January 2012
Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior.
Warner-Schmidt, J.L., Schmidt, E.F., Marshall, J.J., Rubin, A.J., Arango-Lievano, M., Kaplitt, M.G., Ibanez-Tallon, I., Heintz, N. and Greengard, P.
Proceedings of the National Academy of Sciences of the United States of America 109
(28): 11360-11365.
10 July 2012
Weiterbildungssituation kardiale Magnetresonanztomographie: Update 2012.
Wassmuth, R., Schulz-Menger, J., Fleck, E., Hombach, V., Katus, H., Strasser, R.H. and Thiele, H.
Kardiologe 6
(5): 439-442.
October 2012
MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults.
Wefers, B., Hitz, C., Hoelter, S.M., Truembach, D., Hansen, J., Weber, P., Puetz, B., Deussing, J.M., de Angelis, M.H., Roenneberg, T., Zheng, F., Alzheimer, C., Silva, A., Wurst, W. and Kuehn, R.
PLoS ONE 7
(4): e35035.
18 April 2012
Gene editing in one-cell embryos by zinc-finger and TAL nucleases.
Wefers, B., Meyer, M., Hensler, S., Panda, S., Ortiz, O., Wurst, W. and Kühn, R.
Current Protocols in Mouse Biology 2
: 347-364.
December 2012
Amorfrutins are potent antidiabetic dietary natural products.
Weidner, C., de Groot, J.C., Prasad, A., Freiwald, A., Quedenau, C., Kliem, M., Witzke, A., Kodelja, V., Han, C.T., Giegold, S., Baumann, M., Klebl, B., Siems, K., Müller-Kuhrt, L., Schürmann, A., Schüler, R., Pfeiffer, A.F.H., Schroeder, F.C., Büssow, K. and Sauer, S.
Proceedings of the National Academy of Sciences of the United States of America 109
(19): 7257-7262.
8 May 2012
Modulation of distinct isoforms of L-type calcium channels by Gq-coupled receptors in Xenopus oocytes: Antagonistic effects of Gβγ and protein kinase C.
Weiss, S., Keren-Raifman, T., Oz, S., Ben Mocha, A., Haase, H. and Dascal, N.
Channels 6
(6): 426-437.
1 November 2012
The transcription factor c-Maf in sensory neuron development.
Wende, H., Lechner, S.G. and Birchmeier, C.
Transcription 3
(6): 285-289.
November 2012
The transcription factor c-Maf controls touch receptor development and function.
Wende, H., Lechner, S.G., Cheret, C., Bourane, S., Kolanczyk, M.E., Pattyn, A., Reuter, K., Munier, F.L., Carroll, P., Lewin, G.R. and Birchmeier, C.
Science 335
(6074): 1373-1376.
16 March 2012
The miRNA-kallikrein axis of interaction: a new dimension in the pathogenesis of prostate cancer.
White, N.M.A., Youssef, Y.M., Fendler, A., Stephan, C., Jung, K. and Yousef, G.M.
Biological Chemistry 393
(5): 379-389.
May 2012
Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition.
Wilde, S., Sommermeyer, D., Leisegang, M., Frankenberger, B., Mosetter, B., Uckert, W. and Schendel, D.J.
Journal of Immunology 189
(2): 598-605.
15 July 2012
Endocytic receptor-mediated control of morphogen signaling.
Willnow, T.E., Christ, A. and Hammes, A.
Development 139
(23): 4311-4319.
1 December 2012
Direct binding between Orai1 and AC8 mediates dynamic interplay between Ca2+ and cAMP signaling.
Willoughby, D., Everett, K.L., Halls, M.L., Pacheco, J., Skroblin, P., Vaca, L., Klussmann, E. and Cooper, D.M.
Science Signaling 5
(219): ra29.
10 April 2012
A key phosphorylation site in AC8 mediates regulation of Ca2+-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex.
Willoughby, D., Halls, M.L., Everett, K.L., Skroblin, P., Klussmann, E. and Cooper, D.M.F.
Journal of Cell Science 125
(Pt 23): 5850-5859.
1 December 2012
Comparison of three multichannel transmit/receive radiofrequency coil configurations for anatomic and functional cardiac MRI at 7.0T: implications for clinical imaging.
Winter, L., Kellman, P., Renz, W., Graessl, A., Hezel, F., Thalhammer, C., von Knobelsdorff-Brenkenhoff, F., Tkachenko, V., Schulz-Menger, J. and Niendorf, T.
European Radiology 22
(10): 2211-2220.
October 2012
Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma or leukemia.
Witt, O., Milde, T., Deubzer, H.E., Oehme, I., Witt, R., Kulozik, A., Eisenmenger, A., Abel, U. and Karapanagiotou-Schenkel, I.
Klinische Padiatrie 224
(6): 398-403.
October 2012
Cholinergic receptors in the murine oviduct: inventory and coupling to intracellular calcium concentration.
Wolff, M., Noreikat, K., Ibanez-Tallon, I., Lips, K.S., Koelle, S. and Kummer, W.
Life Sciences 91
(21-22): 1003-1008.
27 November 2012
Lesion morphology at 7 Tesla MRI differentiates Susac syndrome from multiple sclerosis.
Wuerfel, J., Sinnecker, T., Ringelstein, E.B., Jarius, S., Schwindt, W., Niendorf, T., Paul, F., Kleffner, I. and Doerr, J.
Multiple Sclerosis Journal 18
(11): 1592-1599.
November 2012
Intrahepatic transplantation of CD34(+) cord blood stem cells into newborn and adult NOD/SCID mice induce differential organ engraftment.
Wulf-Goldenberg, A., Keil, M., Fichtner, I. and Eckert, K.
Tissue & Cell 44
(2): 80-86.
April 2012
Anton Sticker (1861-1944) und das Sticker-Sarkom des Hundes. Ein aktuelles Modell fuer infektioese Krebszellen [Anton Sticker (1861-1944) and the Sticker's sarcoma of dogs. A current model for infectious cancer cells].
Wunderlich, V.
Tieraerztliche Praxis Kleintiere 40
(6): 432-437.
2012
Safety aspects of deep sedation during catheter ablation of atrial fibrillation.
Wutzler, A., Rolf, S., Huemer, M., Parwani, A.S., Boldt, L.H., Herberger, E., Hohenbichler, K., Dietz, R. and Haverkamp, W.
Pacing and Clinical Electrophysiology 35
(1): 38-43.
January 2012
Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC.
Xie, J., Huppa, J.B., Newell, E.W., Huang, J., Ebert, P.J.R., Li, Q.J. and Davis, M.M.
Nature Immunology 13
(7): 674-80.
July 2012
Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours.
Yamada, T., Waller, A.S., Raes, J., Zelezniak, A., Perchat, N., Perret, A., Salanoubat, M., Patil, K.R., Weissenbach, J. and Bork, P.
Molecular Systems Biology 8
: 581.
8 May 2012
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.
Yndestad, A., Finsen, A.V., Ueland, T., Husberg, C., Dahl, C.P., Oie, E., Vinge, L.E., Sjaastad, I., Sandanger, O., Ranheim, T., Dickstein, K., Kjekshus, J., Damas, J.K., Fiane, A.E., Hilfiker-Kleiner, D., Lipp, M., Gullestad, L., Christensen, G. and Aukrust, P.
PLoS ONE 7
(3): e33038.
12 March 2012
A novel titin mutation in adult-onset familial dilated cardiomyopathy.
Yoskovitz, G., Peled, Y., Gramlich, M., Lahat, H., Resnik-Wolf, H., Feinberg, M.S., Afek, A., Pras, E., Arad, M., Gerull, B. and Freimark, D.
American Journal of Cardiology 109
(11): 1644-1650.
1 June 2012
Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.
Yu, J., Valerius, M.T., Duah, M., Staser, K., Hansard, J.K., Guo, J.J., McMahon, J., Vaughan, J., Faria, D., Georgas, K., Rumballe, B., Ren, Q., Krautzberger, A.M., Junker, J.P., Thiagarajan, R.D., Machanick, P., Gray, P.A., van Oudenaarden, A., Rowitch, D.H., Stiles, C.D., Ma, Q., Grimmond, S.M., Bailey, T.L., Little, M.H. and McMahon, A.P.
Development 139
(10): 1863-1873.
May 2012
Detection for gene-gene co-association via kernel canonical correlation analysis.
Yuan, Z., Gao, Q., He, Y., Zhang, X., Li, F., Zhao, J. and Xue, F.
BMC Genetics 13
: 83.
8 October 2012
Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling.
Yuan, Y., Failmezger, H., Rueda, O.M., Ali, H.R., Graef, S., Chin, S.F., Schwarz, R.F., Curtis, C., Dunning, M.J., Bardwell, H., Johnson, N., Doyle, S., Turashvili, G., Provenzano, E., Aparicio, S., Caldas, C. and Markowetz, F.
Science Translational Medicine 4
(157): 157ra143.
24 October 2012
The protease-activated receptor 1 possesses a functional and cleavable signal peptide which is necessary for receptor expression.
Zampatis, D.E., Rutz, C., Furkert, J., Schmidt, A., Wuestenhagen, D., Kubick, S., Tsopanoglou, N.E. and Schuelein, R.
FEBS Letters 586
(16): 2351-2359.
31 May 2012
Aliskiren for the treatment of essential hypertension under real-life practice conditions: design and baseline data of the prospective 3A registry.
Zeymer, U., Dechend, R., Deeg, E., Kaiser, E., Senges, J., Pittrow, D. and Schmieder, R.
International Journal of Clinical Practice 66
(3): 251-261.
March 2012
Involvement of claudins in zebrafish brain ventricle morphogenesis.
Zhang, J., Liss, M., Wolburg, H., Blasig, I.E. and Abdelilah-Seyfried, S.
Annals of the New York Academy of Sciences 1257
(1): 193-198.
June 2012
Immune surveillance and therapy of lymphomas driven by Epstein-Barr-Virus protein LMP1 in a mouse model.
Zhang, B., Kracker, S., Yasuda, T., Casola, S., Vanneman, M., Hömig-Hölzel, C., Wang, Z., Derudder, E., Li, S., Chakraborty, T., Cotter, S.E., Koyama, S., Currie, T., Freeman, G.J., Kutok, J.L., Rodig, S.J., Dranoff, G. and Rajewsky, K.
Cell 148
(4): 739-751.
17 February 2012
Protein-mediated protection as the predominant mechanism for defining processed mRNA termini in land plant chloroplasts.
Zhelyazkova, P., Hammani, K., Rojas, M., Voelker, R., Vargas-Suarez, M., Boerner, T. and Barkan, A.
Nucleic Acids Research 40
(7): 3092-3105.
1 April 2012
The primary transcriptome of barley chloroplasts: numerous noncoding RNAs and the dominating role of the plastid-encoded RNA polymerase.
Zhelyazkova, P., Sharma, C.M., Foerstner, K.U., Liere, K., Vogel, J. and Boerner, T.
Plant Cell 24
(1): 123-136.
January 2012
T cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing.
Zhou, Q., Schneider, I.C., Edes, I., Honegger, A., Bach, P., Schoenfeld, K., Schambach, A., Wels, W.S., Kneissl, S., Uckert, W. and Buchholz, C.J.
Blood 120
(22): 4334-4342.
22 November 2012
Actin filament elasticity and retrograde flow shape the force-velocity relation of motile cells.
Zimmermann, J., Brunner, C., Enculescu, M., Goegler, M., Ehrlicher, A., Kaes, J. and Falcke, M.
Biophysical Journal 102
(2): 287-295.
18 January 2012
OCT4 and the acquisition of oocyte developmental competence during folliculogenesis.
Zuccotti, M., Merico, V., Belli, M., Mulas, F., Sacchi, L., Zupan, B., Redi, C.A., Prigione, A., Adjaye, J., Bellazzi, R. and Garagna, S.
International Journal of Developmental Biology 56
(10-12): 853-858.
2012
Membrane topology and intracellular processing of cyclin M2 (CNNM2).
de Baaij, J.H.F., Stuiver, M., Meij, I.C., Lainez, S., Kopplin, K., Venselaar, H., Mueller, D., Bindels, R.J.M. and Hoenderop, J.G.J.
Journal of Biological Chemistry 287
(17): 13644-13655.
20 April 2012
Bmp signaling exerts opposite effects on cardiac differentiation.
de Pater, E., Ciampricotti, M., Priller, F., Veerkamp, J., Strate, I., Smith, K., Lagendijk, A.K., Schilling, T.F., Herzog, W., Abdelilah-Seyfried, S., Hammerschmidt, M. and Bakkers, J.
Circulation Research 110
(4): 578-587.
17 February 2012
Risk factors for malignant ventricular arrhythmias in lamin A/C mutation carriers a European cohort study.
van Rijsingen, I.A.W., Arbustini, E., Elliott, P.M., Mogensen, J., Hermans-van Ast, J.F., van der Kooi, A.J., van Tintelen, J.P., van den Berg, M.P., Pilotto, A., Pasotti, M., Jenkins, S., Rowland, C., Aslam, U., Wilde, A.A.M., Perrot, A., Pankuweit, S., Zwinderman, A.H., Charron, P. and Pinto, Y.M.
Journal of the American College of Cardiology 59
(5): 493-500.
31 January 2012
Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells.
van der Meulen, T., Xie, R., Kelly, O.G., Vale, W.W., Sander, M. and Huising, M.O.
PLoS ONE 7
(12): e52181.
14 December 2012
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
von Eyss, B., Maaskola, J., Memczak, S., Möllmann, K., Schuetz, A., Loddenkemper, C., Tanh, M.D., Otto, A., Muegge, K., Heinemann, U., Rajewsky, N. and Ziebold, U.
EMBO Journal 31
(4): 972-985.
15 February 2012
Complementary assessment of aortic bioprosthetic dysfunction using cardiac magnetic resonance imaging and computed tomography.
von Knobelsdorff-Brenkenhoff, F., Roettgen, R. and Schulz-Menger, J.
Journal of Heart Valve Disease 21
(1): 20-22.
January 2012
Book Section
The German healthcare system.
Döring, A. and Paul, F.
In:
Healthcare Overview.
Advances in Predictive, Preventive and Personalised Medicine, 1
.
Springer, Dordrecht, Netherlands, 45-67.
ISBN 9789400746022
17 July 2012
Genetisch veraenderte Tiere.
Kühn, R. and Wurst, W.
In:
Handbuch der Psychopharmakotherapie.
Springer, 149-167.
ISBN 978-3-642-19843-4
2012
Natural antisense transcripts within pseudogenes: an EST survey.
Muro, E.M. and Andrade-Navarro, M.A.
In:
Non-coding RNAs and epigenetic regulation of gene expression : drivers of natural selection.
Caister Academic Press, Norfolk, 99-108.
ISBN 978-1-904455-94-3
February 2012
MicroRNAs in embryonic stem cells.
Orlanski, S. and Bergman, Y.
In:
Epigenomics: from chromatin biology to therapeutics.
Cambridge University Press, Cambridge, 163-178.
ISBN 9780511777271
2012
Paired sage-microarray expression data sets reveal antisense transcripts differentially expressed in embryonic stem cell differentiation.
Sandie, R., Porter, C.J., Palidwor, G.A., Price, F., Krzyzanowski, P.M., Muro, E.M., Hoersch, S., Smith, M., Campbell, P.A., Perez-Iratxeta, C., Rudnicki, M.A. and Andrade-Navarro, M.A.
In:
Computational Biology of Embryonic Stem Cells.
Bentham, Oak Park, 193-215.
ISBN 978-1-608-05025-3
2012
Peyton Rous: a centennial tribute to the founding father of cancer virology.
Wunderlich, V. and Kunze, P.
In:
Cancer Associated Viruses.
Current Cancer Research
.
Springer Science and Business Media, New York, 1-23.
ISBN 978-1-4419-9999-3
2012
Conference or Workshop Item
Neue Antihypertensiva in Sicht [New antihypertensive drugs].
Derer, W., Mueller, D.N. and Dechend, R.
In: UNSPECIFIED.
8 March 2012
Praeklinische Validierung fuer das US-gestuetzte Navigationssystem Liver Track.
Eulenstein, S., Jentsch, M. and Schlag, P.M.
In: Annual Meeting on CURAC (Computer- und Roboterassistierte Chirurgie), 15 Nov 2012, Duesseldorf.
2012
Random caustics and intensity fluctuations in weakly disordered media.
Fleischmann, R., Metzger, J. and Geisel, T.
In: Frontiers in Optics 2012/Laser Science XXVIII, 14-18 Oct 2012, Rochester, NY, USA.
2012
The effects of finite populations and selection on the emergence of signaling.
Harrington, K.I., Ozisik, A.P. and Pollack, J.B.
In: 13th International Conference on the Synthesis and Simulation of Living Systems (ALIFE 2012), 19-22 Jul 2012, East Lansing, Michigan, USA.
July 2012
Autoconstructive evolution for structural problems.
Harrington, K.I., Spector, L., Pollack, J.B. and O'Reilly, U.M.
In: GECCO '12: Genetic and Evolutionary Computation Conference, 7-11 Jul 2012, Philadelphia, PA, USA.
July 2012
The effects of tags on the evolution of honest signaling.
Ozisik, A.P. and Harrington, K.I.
In: GECCO '12: Genetic and Evolutionary Computation Conference, 7-11 Jul 2012, Philadelphia, PA, USA.
July 2012
Tag-based modularity in tree-based genetic programming.
Spector, L., Harrington, K. and Helmuth, T.
In: GECCO '12: Genetic and Evolutionary Computation Conference, 7-11 Jul 2012, Philadelphia, PA, USA.
July 2012
Review
Binding sites in membrane proteins: diversity, druggability and prospects.
Adams, R., Worth, C.L., Guenther, S., Dunkel, M., Lehmann, R. and Preissner, R.
European Journal of Cell Biology 91
(4): 326-339.
April 2012
Peer2ref: a peer-reviewer finding web tool that uses author disambiguation.
Andrade-Navarro, M.A., Palidwor, G.A. and Perez-Iratxeta, C.
BioData Mining 5
(1): 14.
7 September 2012
Experimental evidence for sparse firing in the neocortex.
Barth, A.L. and Poulet, J.F.A.
Trends in Neurosciences 35
(6): 345-355.
June 2012
Mesenchymal stromal cells (MSCs): science and f(r)iction.
Bieback, K., Wuchter, P., Besser, D., Franke, W., Becker, M., Ott, M., Pacher, M., Ma, N., Stamm, C., Klueter, H., Mueller, A. and Ho, A.D.
Journal of Molecular Medicine 90
(7): 773-782.
July 2012
Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy.
Borisow, N., Doering, A., Pfueller, C.F., Paul, F., Doerr, J. and Hellwig, K.
EPMA Journal 3
(1): 9.
22 June 2012
Brain renin-angiotensin system in hypertension, cardiac hypertrophy, and heart failure.
Campos, L.A., Bader, M. and Baltatu, O.C.
Frontiers in Physiology 2
: 115.
3 January 2012
Role of β(1)-adrenoceptor autoantibodies in the pathogenesis of dilated cardiomyopathy.
Dandel, M., Wallukat, G., Potapov, E. and Hetzer, R.
Immunobiology 217
(5): 511-520.
May 2012
Pushing the resolution limits in cryo electron tomography of biological structures.
Diebolder, C.A., Koster, A.J. and Koning, R.I.
Journal of Microscopy 248
(1): 1-5.
October 2012
Human induced pluripotent stem cells--from mechanisms to clinical applications.
Drews, K., Jozefczuk, J., Prigione, A. and Adjaye, J.
Journal of Molecular Medicine 90
(7): 735-745.
July 2012
Structural insights into dynamin-mediated membrane fission.
Faelber, K., Held, M., Gao, S., Posor, Y., Haucke, V., Noe, F. and Daumke, O.
Structure 20
(10): 1621-1628.
10 October 2012
Therapeutic targeting of the angiotensin-converting enzyme 2/Angiotensin-(1-7)/Mas cascade in the renin-angiotensin system: a patent review.
Ferreira, A.J., Bader, M. and Santos, R.A.S.
Expert Opinion on Therapeutic Patents 22
(5): 567-574.
May 2012
Evolution of protein domain architectures.
Forslund, K. and Sonnhammer, E.L.L.
Methods in Molecular Biology 856
: 187-216.
2012
Emergence and evolution of the renin-angiotensin-aldosterone system.
Fournier, D., Luft, F.C., Bader, M., Ganten, D. and Andrade-Navarro, M.A.
Journal of Molecular Medicine 90
(5): 495-508.
May 2012
Targeting MET in cancer: rationale and progress.
Gherardi, E., Birchmeier, W., Birchmeier, C. and Woude, G.V.
Nature Reviews Cancer 12
(2): 89-103.
February 2012
Vasodilator signals from perivascular adipose tissue.
Gollasch, M.
British Journal of Pharmacology 165
(3): 633-642.
12 February 2012
Finding the will and the way of ERAD substrate retrotranslocation.
Hampton, R.Y. and Sommer, T.
Current Opinion in Cell Biology 24
(4): 460-466.
August 2012
It takes two to tango: IκBs, the multifunctional partners of NF-κB.
Hinz, M., Coel Arslan, S. and Scheidereit, C.
Immunological Reviews 246
(1): 59-76.
March 2012
Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs.
Höpken, U.E. and Rehm, A.
Journal of Molecular Medicine 90
(11): 1237-1245.
November 2012
Drug discovery in the age of systems biology: the rise of computational approaches for data integration.
Iskar, M., Zeller, G., Zhao, X.M., van Noort, V. and Bork, P.
Current Opinion in Biotechnology 23
(4): 609-616.
August 2012
Neuromyelitis optica spectrum disorders in patients with myasthenia gravis: ten new aquaporin-4 antibody positive cases and a review of the literature.
Jarius, S., Paul, F., Franciotta, D., de Seze, J., Muench, C., Salvetti, M., Ruprecht, K., Liebetrau, M., Wandinger, K., Akman-Demir, G., Melms, A., Kristoferitsch, W. and Wildemann, B.
Multiple Sclerosis Journal 18
(8): 1135-1143.
August 2012
How anti-neutrophil cytoplasmic autoantibodies activate neutrophils.
Kettritz, R.
Clinical and Experimental Immunology 169
(3): 220-228.
September 2012
The essence on mass spectrometry based microbial diagnostics.
Kliem, M. and Sauer, S.
Current Opinion in Microbiology 15
(3): 397-402.
June 2012
Guidelines for the use and interpretation of assays for monitoring autophagy.
Klionsky, D.J., Abdalla, F.C., Abeliovich, H., Abraham, R.T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Milojkovic, A. and Simon, A.K.
Autophagy 8
(4): 445-544.
April 2012
Hydrogen sulfide: potent regulator of vascular tone and stimulator of angiogenesis.
Koehn, C., Dubrovska, G., Huang, Y. and Gollasch, M.
International Journal of Biomedical Science 8
(2): 81-86.
June 2012
XDSAPP: a graphical user interface for the convenient processing of diffraction data using XDS.
Krug, M., Weiss, M.S., Heinemann, U. and Mueller, U.
Journal of Applied Crystallography 45
(3): 568-572.
June 2012
Computational approaches to discovering noncoding RNA.
Krzyzanowski, P.M., Muro, E.M. and Andrade-Navarro, M.A.
Wiley Interdisciplinary Reviews: RNA 3
(4): 567-579.
July 2012
Limiting factors in single particle cryo electron tomography.
Kudryashev, M., Castaño-Díez, D. and Stahlberg, H.
Computational and Structural Biotechnology Journal 1
(2): e201207002.
July 2012
Stomatin-domain proteins.
Lapatsina, L., Brand, J., Poole, K., Daumke, O. and Lewin, G.R.
European Journal of Cell Biology 91
(4): 240-245.
April 2012
Neurodegeneration in multiple sclerosis: novel treatment strategies.
Luessi, F., Siffrin, V. and Zipp, F.
Expert Review of Neurotherapeutics 12
(9): 1061-1077.
September 2012
Molecular mechanisms of arterial stiffness: new insights.
Luft, F.C.
Journal of the American Society of Hypertension 6
(6): 436-438.
November 2012
Neural regulation of the immune system modulates hypertension-induced target-organ damage.
Luft, F.C.
Journal of the American Society of Hypertension 6
(1): 23-26.
January 2012
Immune mechanisms in angiotensin II-induced target-organ damage.
Luft, F.C., Dechend, R. and Mueller, D.N.
Annals of Medicine 44
(Suppl 1): S49-S54.
June 2012
Cardiovascular medications in angiogenesis- how to avoid the sting in the tail.
Ma, C., Wang, Q., Man, Y. and Kemmner, W.
International Journal of Cancer 131
(6): 1249-1259.
15 September 2012
Transcriptome-wide analysis of protein-RNA interactions using high-throughput sequencing.
Milek, M., Wyler, E. and Landthaler, M.
Seminars in Cell & Developmental Biology 23
(2): 206-212.
April 2012
Prorenin receptor regulates more than the renin-angiotensin system.
Mueller, D.N., Binger, K.J. and Riediger, F.
Annals of Medicine 44
(Suppl 1): S43-S48.
June 2012
Evolutionary molecular medicine.
Nesse, R.M., Ganten, D., Gregory, T.R. and Omenn, G.S.
Journal of Molecular Medicine 90
(5): 509-522.
May 2012
Sortilin: a receptor to regulate neuronal viability and function.
Nykjaer, A. and Willnow, T.E.
Trends in Neurosciences 35
(4): 261-270.
April 2012
FOXOs and sirtuins in vascular growth, maintenance, and aging.
Oellerich, M.F. and Potente, M.
Circulation Research 110
(9): 1238-51.
27 April 2012
Functional significance of cleavable signal peptides of G protein-coupled receptors.
Schuelein, R., Westendorf, C., Krause, G. and Rosenthal, W.
European Journal of Cell Biology 91
(4): 294-299.
April 2012
Instruction of mesenchymal cell fate by the transcription factor C/EBPbeta.
Smink, J.J. and Leutz, A.
Gene 497
(1): 10-17.
10 April 2012
The Sleeping Beauty transposon system for clinical applications.
Swierczek, M., Izsvak, Z. and Ivics, Z.
Expert Opinion on Biological Therapy 12
(2): 139-153.
February 2012
cGMP signaling and branching of sensory axons in the spinal cord.
Ter-Avetisyan, G., Troester, P., Schmidt, H. and Rathjen, F.G.
Future Neurology 7
(5): 639-651.
September 2012
Fundamental properties of Ca(2+) signals.
Thurley, K., Skupin, A., Thul, R. and Falcke, M.
Biochimica et Biophysica Acta - General Subjects 1820
(8): 1185-1194.
August 2012
A-kinase anchoring proteins as potential drug targets.
Troeger, J., Moutty, M.C., Skroblin, P. and Klussmann, E.
British Journal of Pharmacology 166
(2): 420-433.
May 2012
Angiogenic growth factors in the diagnosis and prediction of pre-eclampsia.
Verlohren, S., Stepan, H. and Dechend, R.
Clinical Science 122
(2): 43-52.
1 January 2012
Inhibition of the renin-angiotensin-aldosterone system: is there room for dual blockade in the cardiorenal continuum?
Volpe, M., Danser, A.H., Menard, J., Waeber, B., Mueller, D.N., Maggioni, A.P. and Ruilope, L.M.
Journal of Hypertension 30
(4): 647-654.
April 2012
Generating cells of the gastrointestinal system: current approaches and applications for the differentiation of human pluripotent stem cells.
Wang, A. and Sander, M.
Journal of Molecular Medicine 90
(7): 763-71.
July 2012
Dual RNA-seq of pathogen and host.
Westermann, A.J., Gorski, S.A. and Vogel, J.
Nature Reviews Microbiology 10
(9): 618-630.
September 2012
Neuromyelitis optica.
Wildemann, B., Jarius, S. and Paul, F.
Aktuelle Neurologie 39
(1): 33-41.
February 2012
Quantitative intensity-based FRET approaches - a comparative snapshot.
Zeug, A., Woehler, A., Neher, E. and Ponimaskin, E.
Biophysical Journal 103
(9): 1821-1827.
7 November 2012
Cardiovascular magnetic resonance imaging in ischemic heart disease.
von Knobelsdorff-Brenkenhoff, F. and Schulz-Menger, J.
Journal of Magnetic Resonance Imaging 36
(1): 20-38.
July 2012
Letter
Editorial authors' reply to Freedhoff: "Advice to avoid low carbohydrate-high protein diets is not evidence based".
Floegel, A. and Pischon, T.
British Medical Journal 345
(7869): e5109.
6 August 2012
Guiding the molecular diagnosis of hypertrophic cardiomyopathy.
Geier, C., Schulze-Bahr, E. and Bonne, G.
Journal of Thoracic and Cardiovascular Surgery 143
(5): 1234.
May 2012
Improved linear mixed models for genome-wide association studies.
Listgarten, J., Lippert, C., Kadie, C.M., Davidson, R.I., Eskin, E. and Heckerman, D.
Nature Methods 9
(6): 525-526.
30 May 2012
An Experimental Procedure Paid for by the General Public.
Mann, J., Hilgers, K., Veelken, R. and Luft, F.C.
Deutsches Aerzteblatt International 109
(17): 311-312.
April 2012
Adrenergic cardiovascular control before and after removal of stimulatory alpha-1 adrenoreceptor antibodies.
Schroeder, C., Stabroth, C., Luft, F.C. and Jordan, J.
Hypertension 59
(2): e6-e7.
February 2012
NIH-defined graft-versus-host disease after reduced intensity or myeloablative conditioning in patients with acute myeloid leukemia.
Terwey, T.H., Vega-Ruiz, A., Hemmati, P.G., Martus, P., Dietz, E., le Coutre, P., Massenkeil, G., Doerken, B. and Arnold, R.
Leukemia 26
(3): 536-542.
March 2012
Fatigue in multiple sclerosis: which patient should be referred to a sleep specialist?
Veauthier, C. and Paul, F.
Multiple Sclerosis Journal 18
(2): 248-249.
February 2012
Editorial
IFPA Meeting 2011 workshop report I: Placenta: Predicting future health; roles of lipids in the growth and development of feto-placental unit; placental nutrient sensing; placental research to solve clinical problems - a translational approach.
Acharya, G., Albrecht, C., Benton, S.J., Cotechini, T., Dechend, R., Dilworth, M.R., Duttaroy, A.K., Grotmol, T., Heazell, A.E., Jansson, T., Johnstone, E.D., Jones, H.N., Jones, R.L., Lager, S., Laine, K., Nagirnaja, L., Nystad, M., Powell, T., Redman, C., Sadovsky, Y., Sibley, C., Troisi, R., Wadsack, C., Westwood, M. and Lash, G.E.
Placenta 33
(Suppl): S4-S8.
February 2012
New therapeutic pathways in the RAS.
Bader, M., Santos, R.A., Unger, T. and Steckelings, U.M.
Journal of the Renin Angiotensin Aldosterone System 13
(4): 505-508.
December 2012
Stem cell biology-from basic research to regenerative medicine.
Besser, D.
Journal of Molecular Medicine 90
(7): 731-733.
July 2012
Code breaking: the RNAPII modification code in pluripotency.
Brookes, E. and Pombo, A.
Cell Cycle 11
(7): 1267-1268.
1 April 2012
Placenta messages to the mother: not just debris.
Dechend, R. and Staff, A.C.
Hypertension 59
(2): 191-193.
February 2012
Kommunikationstechnologie, Telematik und Robotik : Spagat zwischen Vision und Realitaet [Communication technology, telematics and robotics : balance between vision and reality].
Feussner, H. and Schlag, P.M.
Onkologe 18
(5): 386-388.
May 2012
The Case: Intractable diuretic resistance in a young woman - The Diagnosis: Common iliac artery to common iliac vein AV fistula.
Flenner, E., Elgeti, F., Luft, F.C. and Kettritz, R.
Kidney International 81
(2): 221-222.
2 January 2012
Low carbohydrate-high protein diets.
Floegel, A. and Pischon, T.
British Medical Journal 345
(7864): e3801.
19 June 2012
Tissue engineering: Blood vessels on a chip.
Franco, C. and Gerhardt, H.
Nature 488
(7412): 465-466.
23 August 2012
The evolution of evolutionary molecular medicine : Genomics are transforming evolutionary biology into a science with new importance for modern medicine.
Ganten, D. and Nesse, R.
Journal of Molecular Medicine 90
(5): 467-470.
May 2012
Saeure-Basen-Haushalt [Acid-base balance].
Hoyer, J. and Kettritz, R.
Nephrologe 7
(6): 457-459.
November 2012
When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes.
Junker, J.P. and van Oudenaarden, A.
Molecular Cell 45
(4): 437-438.
24 February 2012
Novel c.367_369del LMNA mutation manifesting as severe arrhythmias, dilated cardiomyopathy, and myopathy.
Keller, H., Finsterer, J., Steger, C., Wexberg, P., Gatterer, E., Khazen, C., Stix, G., Gerull, B., Hoeftberger, R. and Weidinger, F.
Heart & Lung 41
(4): 382-386.
July 2012
Seeing the sodium in a patient with hypernatremia.
Kopp, C., Linz, P., Hammon, M., Schoefl, C., Grauer, M., Eckardt, K.U., Cavallaro, A., Uder, M., Luft, F.C. and Titze, J.
Kidney International 82
(12): 1343-1344.
2 December 2012
uPAR signaling is under par for the podocyte course.
Luft, F.C.
Journal of Molecular Medicine 90
(12): 1357-1359.
December 2012
Does diabetes really cause bone disease?
Luft, F.C.
Journal of Molecular Medicine 90
(11): 1233-1235.
November 2012
Staphylococcus aureus, Toll-like receptors, superantigens, and their derivatives.
Luft, F.C.
Journal of Molecular Medicine 90
(10): 1091-1093.
October 2012
Merely miR210 in mesenchymal stem cells-one size fits all.
Luft, F.C.
Journal of Molecular Medicine 90
(9): 983-985.
September 2012
Mindin your own business.
Luft, F.C.
Journal of Molecular Medicine 90
(8): 861-863.
August 2012
Will the real angiotensin converting enzyme please stand up?
Luft, F.C.
Journal of Molecular Medicine 90
(6): 609-611.
June 2012
Rats, salt, and history.
Luft, F.C.
Cell Metabolism 15
(2): 129-130.
8 February 2012
A zinc transporter protects from ischemia-reperfusion injury.
Luft, F.C.
Journal of Molecular Medicine 90
(2): 101-103.
February 2012
How calcineurin inhibitors cause hypertension.
Luft, F.C.
Nephrology Dialysis Transplantation 27
(2): 473-475.
February 2012
Whither magnesium?
Luft, F.C.
Clinical Kidney Journal 5
(Suppl 1): i1-i2.
February 2012
CCAAT enhancer-binding proteins have long boney fingers.
Luft, F.C.
Journal of Molecular Medicine 90
(1): 1-3.
January 2012
Fatigue and sleep disorders in multiple sclerosis: is obstructive sleep apnea a link?
Paul, F. and Veauthier, C.
Sleep & Breathing 16
(4): 949-950.
December 2012
Morbus Alzheimer: Sind nicht-steroidale Antiphlogistika und Steroide wirksam? [Alzheimer's disease: are non-steroidal anti-inflammatory drugs effective?].
Peters, O.
Deutsche Medizinische Wochenschrift 137
(50): 2627.
December 2012
Burkitt lymphomagenesis linked to MYC plus PI3K in germinal center B cells.
Sander, S. and Rajewsky, K.
Oncotarget 3
(10): 1066-1067.
28 October 2012
Versorgungsforschung – Notwendigkeit und Chancen [Health service research - necessity and opportunity].
Schmitz, S. and Schlag, P.M.
Onkologe 18
(2): 102-104.
February 2012
The liberation of women from the scourge of cervical cancer.
Schneider, A. and Schlag, P.M.
Onkologe 18
(1): 6-8.
January 2012
Primary malignant tumors of the liver.
Settmacher, U. and Schlag, P.M.
Onkologe 18
(7): 570-572.
July 2012
Gender equality: is it real?
Simon, K., Athanassakis, I., Powrie, F. and Montoya, M.
European Journal of Immunology 42
(12): 3095-6.
December 2012
A TORway to osteolytic disease.
Smink, J.J. and Leutz, A.
Cell Cycle 11
(4): 637-638.
15 February 2012
Where do you come from; where do you go? Pluripotency, differentiation and malfunction of stem cells.
Spagnoli, F.M., Besser, D. and Benitah, S.A.
EMBO Reports 13
(1): 9-11.
January 2012
The investigation of binary PPIs with the classical yeast two-hybrid (Y2H) approach, Y2H variants, and other in vivo methods for PPI mapping.
Suter, B. and Wanker, E.E.
Methods in Molecular Biology 812
: v-vi.
2012
Cardiovascular research funding : European Molecular Biology Organization Awards.
Taylor, J.
Circulation 125
(14): F79-F83.
April 2012
Comment
A case of strange cardiac rhythms.
Kettritz, R. and Luft, F.C.
Clinical Kidney Journal 5
(6): 603-604.
December 2012
Kommentar: Beeinflussen Antidiabetika das Krebsrisiko?
Steinbrecher, A. and Pischon, T.
Diabetologie und Stoffwechsel 7
: 119-120.
2012
This list was generated on Mon Dec 30 06:59:56 2024 UTC.
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