Browse by Research Team

2025

hnRNPA2B1 drives colorectal cancer progression via the circCDYL/EIF4A3/PHF8 axis.
Sun, Y.K., Wang, J.F., Sun, X.W. and Zhang, M.
Kaohsiung Journal of Medical Sciences 41 (3): e12943. March 2025

2024

TransTACs: novel heterobispecific antibodies for targeted protein degradation in cancer therapy.
Walther, W., Torke, S. and Stein, U.
Signal Transduction and Targeted Therapy 9 (1): 331. 26 November 2024

MACC1 revisited - an in-depth review of a master of metastasis.
Schöpe, P.C., Torke, S., Kobelt, D., Kortüm, B., Treese, C., Dumbani, M., Güllü, N., Walther, W. and Stein, U.
Biomarker Research 12 (1): 146. 23 November 2024

Induction of circulating ABCB1 transcripts under platinum-based chemotherapy indicates poor prognosis and a bone micrometastatic phenotype in ovarian cancer patients.
Schwarz, F.M., Kuhlmann, J.D., Kämpfer, J., Klimova, A., Klotz, D.M., Freitag, L., Herrmann, P., Zinnow, V., Smith, J., Scheller, T., Walther, W., Wimberger, P. and Stein, U.
Molecular Cancer 23 (1): 174. 23 August 2024

Literature review: potential non-thermal molecular effects of external radiofrequency electromagnetic fields on cancer.
Dieper, A., Scheidegger, S., Füchslin, R.M., Veltsista, P.D., Stein, U., Weyland, M., Gerster, D., Beck, M., Bengtsson, O., Zips, D. and Ghadjar, P.
International Journal of Hyperthermia 41 (1): 2379992. 17 July 2024

Editorial: The MACC1 network in cancer.
Walther, W., Siegel, F. and Stein, U.
Frontiers in Oncology 13 : 1343812. 5 July 2024

Neighborhood-level inequalities and influencing factors of COVID-19 incidence in berlin based on Bayesian spatial modelling.
Zhuang, S., Wolf, K., Schmitz, T., Roth, A., Sun, Y., Savaskan, N. and Lakes, T.
Sustainable Cities and Society 104 : 105301. May 2024

BTK inhibition limits microglia‑perpetuated CNS inflammation and promotes myelin repair.
Geladaris, A., Torke, S., Saberi, D., Alankus, Y.B., Streit, F., Zechel, S., Stadelmann-Nessler, C., Fischer, A., Boschert, U., Häusler, D. and Weber, M.S.
Acta Neuropathologica 147 (1): 75. 24 April 2024

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies.
Torke, S., Walther, W. and Stein, U.
Cancers 16 (7): 1330. 28 March 2024

Activation of gp130 signaling in T cells drives T(H)17-mediated multi-organ autoimmunity.
Baumgartner, F., Bamopoulos, S.A., Faletti, L., Hsiao, H.J., Holz, M., Gonzalez-Menendez, I., Solé-Boldo, L., Horne, A., Gosavi, S., Özerdem, C., Singh, N., Liebig, S., Ramamoorthy, S., Lehmann, M., Demel, U., Kühl, A.A., Wartewig, T., Ruland, J., Wunderlich, F.T., Schick, M., Walther, W., Rose-John, S., Haas, S., Quintanilla-Martinez, L., Feske, S., Ehl, S., Glauben, R. and Keller, U.
Science Signaling 17 (824): eadc9662. 20 February 2024

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer.
Erdem, M., Lee, K.H., Hardt, M., Regan, J.L., Kobelt, D., Walther, W., Mokrizkij, M., Regenbrecht, C. and Stein, U.
Cancers 16 (3): 604. 31 January 2024

Taste mapping: navigating the spatiotemporal link between diet and colorectal cancer.
Luo, Q., Liu, Y., Bi, M., Kuai, X., Tian, Q., Sun, Y. and Zhuang, S.
IEEE Access 12 : 17735 - 17747. 30 January 2024

Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model.
Mohan, A.M., Prasad, S., Schmitz-Peiffer, F., Lange, C., Lukas, M., Koziolek, E.J., Albrecht, J., Messroghli, D., Stein, U., Ilmer, M., Wang, K., Schober, L., Reul, A., Maurer, J., Friemel, J., Weber, A., Zuellig, R.A., Hantel, C., Fritsch, R., Reincke, M., Pacak, K., Grossman, A.B., Auernhammer, C.J., Beuschlein, F., Brenner, W., Beindorff, N. and Nölting, S.
Endocrine-Related Cancer 31 (1): e230041. January 2024

2023

Establishment and thorough characterization of xenograft (PDX) models derived from patients with pancreatic cancer for molecular analyses and chemosensitivity testing.
Behrens, D., Pfohl, U., Conrad, T., Becker, M., Brzezicha, B., Büttner, B., Wagner, S., Hallas, C., Lawlor, R., Khazak, V., Linnebacher, M., Wartmann, T., Fichtner, I., Hoffmann, J., Dahlmann, M. and Walther, W.
Cancers 15 (24): 5753. 8 December 2023

GIPC1 regulates MACC1-driven metastasis.
Siegel, F., Schmidt, H., Juneja, M., Smith, J., Herrmann, P., Kobelt, D., Sharma, K., Fichtner, I., Walther, W., Dittmar, G., Volkmer, R., Rathjen, F.G., Schlag, P.M. and Stein, U.
Frontiers in Oncology 13 : 1280977. 8 December 2023

Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Yan, S., Schöpe, P.C., Lewis, J., Putzker, K., Uhrig, U., Specker, E., von Kries, J.P., Lindemann, P., Omran, A., Sanchez-Ibarra, H.E., Unger, A., Zischinsky, M.L., Klebl, B., Walther, W., Nazaré, M., Kobelt, D. and Stein, U.
Biomedicine & Pharmacotherapy 168 : 115698. December 2023

H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma.
Phoyen, S., Sanpavat, A., Ma-on, C., Stein, U., Hirankarn, N., Tangkijvanich, P., Jindatip, D., Whongsiri, P. and Boonla, C.
Heliyon 9 (12): e22589. December 2023

Metastasis associated in colorectal cancer 1 (MACC1) mRNA expression is enhanced in sporadic vestibular schwannoma and correlates to deafness.
Breun, M., Flock, K., Feldheim, J., Nattmann, A., Monoranu, C.M., Herrmann, P., Ernestus, R.I., Löhr, M., Hagemann, C. and Stein, U.
Cancers 15 (16): 4089. 14 August 2023

Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.
Alcaniz, J., Winkler, L., Dahlmann, M., Becker, M., Orthmann, A., Haybaeck, J., Krassnig, S., Skofler, C., Kratzsch, T., Kuhn, S.A., Jödicke, A., Linnebacher, M., Fichtner, I., Walther, W. and Hoffmann, J.
Frontiers in Oncology 13 : 1129627. 11 April 2023

Targeting B cells and microglia in multiple sclerosis with Bruton tyrosine kinase inhibitors: a review.
Dybowski, S., Torke, S. and Weber, M.S.
JAMA Neurology 80 (4): 404-414. 1 April 2023

Cantharidin and its analogue norcantharidin inhibit metastasis-inducing genes S100A4 and MACC1.
Schöpe, P.C., Zinnow, V., Ishfaq, M.A., Smith, J., Herrmann, P., Shoemaker, R.H., Walther, W. and Stein, U.
International Journal of Molecular Sciences 24 (2): 1179. 7 January 2023

2022

Immunohistochemical analysis of nicotinamide phosphoribosyltransferase expression in gastric and esophageal adenocarcinoma (AEG).
Arnold, A., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Krenzien, F., Stein, U. and Treese, C.
Gastrointestinal Disorders 4 (4): 333-340. 13 December 2022

MACC1-dependent antitumor effect of curcumin in colorectal cancer.
Güllü, N., Smith, J., Herrmann, P. and Stein, U.
Nutrients 14 (22): 4792. 12 November 2022

The monocyte, a maestro in the tumor microenvironment (TME) of breast cancer.
Amer, H.T., Stein, U. and El Tayebi, H.M.
Cancers 14 (21): 5460. 7 November 2022

Radiofrequency electromagnetic fields cause non-temperature-induced physical and biological effects in cancer cells.
Wust, P., Veltsista, P.D., Oberacker, E., Yavvari, P., Walther, W., Bengtsson, O., Sterner-Kock, A., Weinhart, M., Heyd, F., Grabowski, P., Stintzing, S., Heinrich, W., Stein, U. and Ghadjar, P.
Cancers 14 (21): 5349. 30 October 2022

Bruton's tyrosine kinase inhibitors in multiple sclerosis: pioneering the path towards treatment of progression?
Geladaris, A., Torke, S. and Weber, M.S.
CNS drugs 36 (10): 1019-1030. October 2022

Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis.
Kortüm, B., Radhakrishnan, H., Zincke, F., Sachse, C., Burock, S., Keilholz, U., Dahlmann, M., Walther, W., Dittmar, G., Kobelt, D. and Stein, U.
Oncogene 41 (39): 4446-4458. 23 September 2022

Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas.
Staudacher, J.J., Arnold, A., Kühl, A.A., Pötzsch, M., Daum, S., Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. and Treese, C.
BMC Cancer 22 (1): 953. 5 September 2022

Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker.
Schmid, F., Dahlmann, M., Röhrich, H., Kobelt, D., Hoffmann, J., Burock, S., Walther, W. and Stein, U.
British Journal of Cancer 127 (4): 675-685. 1 September 2022

Small molecule inhibitors for hepatocellular carcinoma: advances and challenges.
Kamal, M.A., Mandour, Y.M., Abd El-Aziz, M.K., Stein, U. and El Tayebi, H.M.
Molecules 27 (17): 5537. 1 September 2022

Core-clock genes regulate proliferation and invasion via a reciprocal interplay with MACC1 in colorectal cancer cells.
Basti, A., Malhan, D., Dumbani, M., Dahlmann, M., Stein, U. and Relógio, A.
Cancers 14 (14): 3458. 16 July 2022

A brief introduction to current cancer gene therapy.
Kobelt, D., Pahle, J. and Walther, W.
Methods in Molecular Biology 2521 (3): 1-21. 23 June 2022

Capillary gel electrophoresis (CGE) for quality control of plasmid DNA in gene therapy: quality control of 20 years stored GMP-grade plasmid DNA.
Schmeer, M., Schleef, M., Shankar, R., Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521 (3): 317-328. 23 June 2022

Claudin-targeted suicide gene therapy for claudin-overexpressing tumor cells by using modified clostridium perfringens enterotoxin (CPE).
Beier, L.S., Piontek, J., Piontek, A., Protze, J., Kobelt, D. and Walther, W.
Methods in Molecular Biology 2521 (3): 173-188. 23 June 2022

Gene gun Her2/neu DNA vaccination: evaluation of vaccine efficacy in a syngeneic Her2/neu mouse tumor model.
Nguyen-Hoai, T., Hohn, O., Pezzutto, A. and Westermann, J.
Methods in Molecular Biology 2521 (3): 129-154. 23 June 2022

A molecularly characterized preclinical platform of subcutaneous renal cell carcinoma (RCC) patient-derived xenograft models to evaluate novel treatment strategies.
Gürgen, D., Becker, M., Dahlmann, M., Flechsig, S., Schaeffeler, E., Büttner, F.A., Schmees, C., Bohnert, R., Bedke, J., Schwab, M., Wendler, J.J., Schostak, M., Jandrig, B., Walther, W. and Hoffmann, J.
Frontiers in Oncology 12 : 889789. 21 June 2022

MACC1-induced collective migration is promoted by proliferation rather than single cell biomechanics.
Hohmann, T., Hohmann, U., Dahlmann, M., Kobelt, D., Stein, U. and Dehghani, F.
Cancers 14 (12): 2857. 9 June 2022

Conventional amphotericin B elicits markers of immunogenic cell death on leukemic blasts, mediates immunostimulatory effects on phagocytic cells, and synergizes with PD-L1 blockade.
Kofla, G., Radecke, C., Frentsch, M., Walther, W., Stintzing, S., Riess, H., Bullinger, L. and Na, I.K.
OncoImmunology 11 (1): 2068109. 25 April 2022

Elevated MACC1 expression in colorectal cancer is driven by chromosomal instability and is associated with molecular subtype and worse patient survival.
Vuaroqueaux, V., Musch, A., Kobelt, D., Risch, T:, Herrmann, P., Burock, S., Peille, A.L., Yaspo, M.L., Fiebig, H.H. and Stein, U.
Cancers 14 (7): 1749. 1 April 2022

Inhibition of MACC1-induced metastasis in esophageal and gastric adenocarcinomas.
Treese, C., Werchan, J., von Winterfeld, M., Berg, E., Hummel, M., Timm, L., Rau, B., Daberkow, O., Walther, W., Daum, S., Kobelt, D. and Stein, U.
Cancers 14 (7): 1773. 31 March 2022

S100A4 is a strong negative prognostic marker and potential therapeutic target in adenocarcinoma of the stomach and esophagus.
Treese, C., Hartl, K., Pötzsch, M., Dahlmann, M., von Winterfeld, M., Berg, E., Hummel, M., Timm, L., Rau, B., Walther, W., Daum, S., Kobelt, D. and Stein, U.
Cells 11 (6): 1056. 21 March 2022

Suicide nanoplasmids coding for ribosome-inactivating proteins.
Mitdank, H., Tröger, M., Sonntag, A., Shirazi, N.A., Woith, E., Fuchs, H., Kobelt, D., Walther, W. and Weng, A.
European Journal of Pharmaceutical Sciences 170 : 106107. 1 March 2022

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.
Ng, Y.L.D., Ramberger, E., Bohl, S.R., Dolnik, A., Steinebach, C., Conrad, T., Müller, S., Popp, O., Kull, M., Haji, M., Gütschow, M., Döhner, H., Walther, W., Keller, U., Bullinger, L., Mertins, P. and Krönke, J.
Nature Communications 13 (1): 1009. 23 February 2022

Real-world evidence for preventive effects of statins on cancer incidence: a trans-atlantic analysis.
Gohlke, B.O., Zincke, F., Eckert, A., Kobelt, D., Preissner, S., Liebeskind, J.M., Gunkel, N., Putzker, K., Lewis, J., Preissner, S., Kortüm, B., Walther, W., Mura, K., Bourne, P.E., Stein, U. and Preissner, R.
Clinical and Translational Medicine 12 (2): e726. 20 February 2022

Obesity, colorectal cancer and MACC1 expression: a possible novel molecular association.
Bähr, I., Jaeschke, L., Nimptsch, K., Janke, J., Herrmann, P., Kobelt, D., Kielstein, H., Pischon, T. and Stein, U.
International Journal of Oncology 60 (2): 17. February 2022

Combination of Wnt/β-catenin targets S100A4 and DKK1 improves prognosis of human colorectal cancer.
Dahlmann, M., Monks, A., Harris, E.D., Kobelt, D., Osterland, M., Khaireddine, F., Herrmann, P., Kemmner, W., Burock, S., Walther, W., Shoemaker, R.H. and Stein, U.
Cancers 14 (1): 37. 2022

Gene therapy of cancer : methods and protocols.
Walther, Wolfgang, ed.
Methods in Molecular Biology, 2521 (3). Springer / Humana Press, New York, NY. ISBN 9781071624401 2022

2021

Insulin-like growth factor binding protein-2 (IGFBP2) is a key molecule in the MACC1-mediated platelet communication and metastasis of colorectal cancer cells.
Haschemi, R., Kobelt, D., Steinwarz, E., Schlesinger, M., Stein, U. and Bendas, G.
International Journal of Molecular Sciences 22 (22): 12195. 11 November 2021

Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.
Dahlmann, M., Gambara, G., Brzezicha, B., Popp, O., Pachmayr, E., Wedeken, L., Pflaume, A., Mokritzkij, M., Gül-Klein, S., Brandl, A., Schweiger-Eisbacher, C., Mertins, P., Hoffmann, J., Keilholz, U., Walther, W., Regenbrecht, C., Rau, B. and Stein, U.
Molecular Cancer 20 (1): 129. 21 October 2021

Effective oncoleaking treatment of pancreatic cancer by claudin-targeted suicide gene therapy with Clostridium perfringens enterotoxin (CPE).
Pahle, J., Kobelt, D., Aumann, J., Behrens, D., Daberkow, O., Mokritzkij, M., Piontek, J., Stein, U. and Walther, W.
Cancers 13 (17): 4393. 1 September 2021

Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin.
Gillissen, B., Richter, A., Essmann, F. and Kemmner, W.
BMC Cancer 21 (1): 971. 30 August 2021

The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt, D., Perez-Hernandez, D., Fleuter, C., Dahlmann, M., Zincke, F., Smith, J., Migotti, R., Popp, O., Burock, S., Walther, W., Dittmar, G., Mertins, P. and Stein, U.
Oncogene 40 (34): 5286-5301. 26 August 2021

M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
Breitkreuz-Korff, O., Tscheik, C., Del Vecchio, G., Dithmer, S., Walther, W., Orthmann, A., Wolburg, H., Haseloff, R.F., Schröder, L., Blasig, I.E. and Winkler, L.
Journal of Controlled Release 330 : 137-148. 10 August 2021

Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology.
Wust, P., Stein, U. and Ghadjar, P.
International Journal of Hyperthermia 38 (1): 715-731. 28 April 2021

MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer.
Imbastari, F., Dahlmann, M., Sporbert, A., Ciolli Mattioli, C., Mari, T., Scholz, F., Timm, L., Twamley, S., Migotti, R., Walther, W., Dittmar, G., Rehm, A. and Stein, U.
Cellular and Molecular Life Sciences 78 (7): 3525-3542. April 2021

Wnt signalling pathway in bladder cancer.
Wu, G., Weng, W., Xia, P., Yan, S., Zhong, C., Xie, L., Xie, Y. and Fan, G.
Cellular Signalling 79 : 109886. March 2021

Systematic identification of MACC1-driven metabolic networks in colorectal cancer.
Lisec, J., Kobelt, D., Walther, W., Mokrizkij, M., Grötzinger, C., Jaeger, C., Baum, K., Simon, M., Wolf, J., Beindorff, N., Brenner, W. and Stein, U.
Cancers 13 (5): 978. 26 February 2021

Thymoquinone: a tie-breaker in SARS-CoV2-infected cancer patients?
Elgohary, S., Elkhodiry, A.A., Amin, N.S., Stein, U. and El Tayebi, H.M.
Cells 10 (2): 302. 2 February 2021

Identification of unique long non-coding RNAs as putative biomarkers for chromophobe renal cell carcinoma.
Wu, G., Xia, P., Yan, S., Chen, D., Xie, L. and Fan, G.
Personalized Medicine 18 (1): 9-19. January 2021

Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine.
Rivera, M., Fichtner, I., Wulf-Goldenberg, A., Sers, C., Merk, J., Patone, G., Alp, K.M., Kanashova, T., Mertins, P., Hoffmann, J., Stein, U. and Walther, W.
Neoplasia 23 (1): 21-35. January 2021

A bioinformatic pipeline to identify biomarkers for metastasis formation from RNA sequencing data.
Dahlmann, M. and Stein, U.S.
Methods in Molecular Biology 2294 : 221-238. 2021

From operating table to laboratory bench: the path toward metastasis research from the clinical setting.
Alberto Vilchez, M. and Rau, B.
Methods in Molecular Biology 2294 : 325-333. 2021

Metastasis : methods and protocols.
Stein, U.S., ed.
Methods in Molecular Biology, 2294 . Springer / Humana Press, New York, NY. ISBN 978-1-0716-1349-8 2021

Patient-derived xenografts from solid tumors (PDX) for models of metastasis.
Wulf-Goldenberg, A., Hoffmann, J., Becker, M., Brzezicha, B. and Walther, W.
Methods in Molecular Biology 2294 : 43-58. 2021

Preface.
Stein, U.S.
Methods in Molecular Biology 2294 : v. 2021

Real-time cell migration monitoring to analyze drug synergism in the scratch assay using the IncuCyte system.
Kobelt, D., Walther, W. and Stein, U.S.
Methods in Molecular Biology 2294 : 133-142. 2021

2020

Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Rau, B., Stein, U. and Treese, C.
Clinical and Translational Oncology 22 (12): 2357-2363. December 2020

Quantification of mRNA expression using single-molecule nanopore sensing.
Rozevsky, Y., Gilboa, T., van Kooten, X.F., Kobelt, D., Huttner, D., Stein, U. and Meller, A.
ACS Nano 14 (10): 13964-13974. 27 October 2020

Better prognosis of gastric cancer patients with high levels of tumor infiltrating lymphocytes is counteracted by PD-1 expression.
Pötzsch, M., Berg, E., Hummel, M., Stein, U., von Winterfeld, M., Jöhrens, K., Rau, B., Daum, S. and Treese, C.
OncoImmunology 9 (1): 1824632. 30 September 2020

Novel targets of protoporphyrin-IX determined by gene expression analysis.
Dai, Y. and Kemmner, W.
International Journal of Clinical Oncology and Cancer Research 5 (3): 56-64. September 2020

Non-thermal effects of radiofrequency electromagnetic fields.
Wust, P., Kortüm, B., Strauss, U., Nadobny, J., Zschaeck, S., Beck, M., Stein, U. and Ghadjar, P.
Scientific Reports 10 (1): 13488. 10 August 2020

Saffron crudes and compounds restrict MACC1-dependent cell proliferation and migration of colorectal cancer cells.
Güllü, N., Kobelt, D., Brim, H., Rahman, S., Timm, L., Smith, J., Soleimani, A., Di Marco, S., Bisti, S., Ashktorab, H. and Stein, U.
Cells 9 (8): 1829. 3 August 2020

In-vitro and in-vivo investigations into the carbene-gold anticancer drug candidates NHC*-Au-SCSNMe(2) and NHC*-Au-S-GLUC against advanced prostate cancer PC3.
Walther, W., Althagafi, D., Curran, D., O'Beirne, C., Mc Carthy, C., Ott, I., Basu, U., Büttner, B., Sterner-Kock, A., Müller-Bunz, H., Sánchez-Sanz, G., Zhu, X. and Tacke, M.
Anti-Cancer Drugs 31 (7): 672-683. August 2020

MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma.
Hohmann, T., Hohmann, U., Kolbe, M.R., Dahlmann, M., Kobelt, D., Stein, U. and Dehghani, F.
Cell Communication and Signaling 18 (1): 85. 5 June 2020

Small ones to fight a big problem-intervention of cancer metastasis by small molecules.
Kobelt, D., Dahlmann, M., Dumbani, M., Güllü, N., Kortüm, B., Vílchez, M.E.A., Stein, U. and Walther, W.
Cancers 12 (6): 1454. 3 June 2020

Pro-inflammatory TNF-α and IFN-γ promote tumor growth and metastasis via induction of MACC1.
Kobelt, D., Zhang, C., Clayton-Lucey, I.A., Glauben, R., Voss, C., Siegmund, B. and Stein, U.
Frontiers in Immunology 11 : 980. 27 May 2020

Restoring treatment response in colorectal cancer cells by targeting MACC1-dependent ABCB1 expression in combination therapy.
Dahlmann, M., Werner, R., Kortüm, B., Kobelt, D., Walther, W. and Stein, U.
Frontiers in Oncology 10 : 599. 23 April 2020

Social media big data-based research on the influencing factors of insomnia and spatiotemporal evolution.
Liu, Y., Luo, Q., Shen, H., Zhuang, S., Xu, C., Dong, Y., Sun, Y., Wang, S. and Deng, H.
IEEE Access 8 : 41516-41529. 28 February 2020

Decoding and targeting the molecular basis of MACC1-driven metastatic spread: lessons from big data mining and clinical-experimental approaches.
Budczies, J., Kluck, K., Walther, W. and Stein, U.
Seminars in Cancer Biology 60 : 365-379. February 2020

Targeting claudin-overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin.
Piontek, A., Eichner, M., Zwanziger, D., Beier, L.S., Protze, J., Walther, W., Theurer, S., Schmid, K.W., Führer-Sakel, D., Piontek, J. and Krause, G.
Molecular Oncology 14 (2): 261-276. February 2020

2019

Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Horst, D., Rau, B., Stein, U. and Treese, C.
Pathology Research and Practice 215 (11): 152662. November 2019

Immunhistochemische Analyse von Bcl-2, nukleärem S100A4, MITF und Ki67 zur Risikostratifizierung von Melanomen im Frühstadium - ein kombinierter immunhistochemischer Score.
Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17 (8): 800-809. August 2019

Immunohistochemical analysis of Bcl-2, nuclear S100A4, MITF and Ki67 for risk stratification of early-stage melanoma - a combined IHC score for melanoma risk stratification.
Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17 (8): 800-808. August 2019

The importance of developing therapies targeting the biological spectrum of metastatic disease.
Zijlstra, A., Von Lersner, A., Yu, D., Borrello, L., Oudin, M., Kang, Y., Sahai, E., Fingleton, B., Stein, U., Cox, T.R., Price, J.T., Kato, Y., Welm, A.L. and Aguirre-Ghiso, J.A.
Clinical and Experimental Metastasis 36 (4): 305-309. August 2019

Non-invasive metastasis prognosis from plasma metabolites in stage II colorectal cancer patients: the DACHS study.
Zaimenko, I., Jaeger, C., Brenner, H., Chang-Claude, J., Hoffmeister, M., Grötzinger, C., Detjen, K., Burock, S., Schmitt, C.A., Stein, U. and Lisec, J.
International Journal of Cancer 145 (1): 221-231. 1 July 2019

Circulating MACC1 transcripts in glioblastoma patients predict prognosis and treatment response.
Hagemann, C., Neuhaus, N., Dahlmann, M., Kessler, A.F., Kobelt, D., Herrmann, P., Eyrich, M., Freitag, B., Linsenmann, T., Monoranu, C.M., Ernestus, R.I., Löhr, M. and Stein, U.
Cancers 11 (6): 825. 13 June 2019

Clinical relevance of circulating MACC1 and S100A4 transcripts for ovarian cancer.
Link, T., Kuhlmann, J.D., Kobelt, D., Herrmann, P., Vassileva, Y., Kramer, M., Frank, K., Göckenjan, M., Wimberger, P. and Stein, U.
Molecular Oncology 13 (5): 1268-1279. May 2019

Saffron: The golden spice with therapeutic properties on digestive diseases.
Ashktorab, H., Soleimani, A., Singh, G., Amr, A., Tabtabaei, S., Latella, G., Stein, U., Akhondzadeh, S., Solanki, N., Gondré-Lewis, M.C., Habtezion, A. and Brim, H.
Nutrients 11 (5): 943. 26 April 2019

A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis.
Heuberger, J., Hill, U., Förster, S., Zimmermann, K., Malchin, V., Kühl, A.A., Stein, U., Vieth, M., Birchmeier, W. and Leutz, A.
Life Science Alliance 2 (1): e201800173. February 2019

Pressurized intraperitoneal aerosol chemotherapy and its effect on gastric-cancer-derived peritoneal metastases: an overview.
Alberto, M., Brandl, A., Garg, P.K., Gül-Klein, S., Dahlmann, M., Stein, U. and Rau, B.
Clinical and Experimental Metastasis 36 (1): 1-14. February 2019

2018

Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients.
Feldheim, J., Kessler, A.F., Schmitt, D., Wilczek, L., Linsenmann, T., Dahlmann, M., Monoranu, C.M., Ernestus, R.I., Hagemann, C. and Löhr, M.
OncoTargets and Therapy 11 : 8673-8684. 4 December 2018

MACC1 - the first decade of a key metastasis molecule from gene discovery to clinical translation.
Radhakrishnan, H., Walther, W., Zincke, F., Kobelt, D., Imbastari, F., Erdem, M., Kortüm, B., Dahlmann, M. and Stein, U.
Cancer and Metastasis Reviews 37 (4): 805-820. December 2018

Mechanisms of targeting the MDM2-p53-FOXM1 axis in well-differentiated intestinal neuroendocrine tumors.
Briest, F., Grass, I., Sedding, D., Moebs, M., Christen, F., Benecke, J., Fuchs, K., Mende, S., Kaemmerer, D., Saenger, J., Kunze, A., Geisler, C., Freitag, H., Lewens, F., Worpenberg, L., Iwaszkiewicz, S., Siegmund, B., Walther, W., Hummel, M. and Grabowski, P.
Neuroendocrinology 107 (1): 1-23. July 2018

Efficient non-viral gene delivery into human hematopoietic stem cells by minicircle Sleeping Beauty transposon vectors.
Holstein, M., Mesa-Nuñez, C., Miskey, C., Almarza, E., Poletti, V., Schmeer, M., Grueso, E., Ordóñez Flores, J.C., Kobelt, D., Walther, W., Aneja, M.K., Geiger, J,, Bonig, H.B., Izsvák, Z., Schleef, M., Rudolph, C., Mavilio, F., Bueren, J.A., Guenechea, G. and Ivics, Z.
Molecular Therapy 26 (4): 1137-1153. 4 April 2018

Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial.
Burock, S., Daum, S., Keilholz, U., Neumann, K., Walther, W. and Stein, U.
BMC Cancer 18 (1): 297. 15 March 2018

Genome-wide analysis of barrett's adenocarcinoma. a first step towards identifying patients at risk and developing therapeutic paths.
Dai, Y., Wang, Q., Gonzalez Lopez, A., Anders, M., Malfertheiner, P., Vieth, M. and Kemmner, W.
Translational Oncology 11 (1): 116-124. February 2018

2017

In colon epithelia, Clostridium perfringens enterotoxin causes focal leaks by targeting claudins which are apically accessible due to tight junction derangement.
Eichner, M., Augustin, C., Fromm, A., Piontek, A., Walther, W., Buecker, R., Fromm, M., Krause, G., Schulzke, J.D., Guenzel, D. and Piontek, J.
Journal of Infectious Diseases 217 (1): 147-157. 27 December 2017

Approaches and techniques to characterize cancer metabolism in vitro and in vivo.
Zaimenko, I., Lisec, J., Stein, U. and Brenner, W.
Biochimica et Biophysica Acta - Reviews on Cancer 1868 (2): 412-419. December 2017

Perspective on the interpretation of research and translation to clinical care with therapy-associated metastatic breast cancer progression as an example.
Fingleton, B., Lange, K., Caldwell, B. and Bankaitis, K.V.
Clinical and Experimental Metastasis 34 (8): 443-447. December 2017

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.
Radhakrishnan, H., Ilm, K., Walther, W., Shirasawa, S., Sasazuki, T., Daniel, P.T., Gillissen, B. and Stein, U.
Cancer Letters 403 : 231-245. 10 September 2017

Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies.
Rohr, U.P., Herrmann, P., Ilm, K., Zhang, H., Lohmann, S., Reiser, A., Muranyi, A., Smith, J., Burock, S., Osterland, M., Leith, K., Singh, S., Brunhoeber, P., Bowermaster, R., Tie, J., Christie, M., Wong, H.L., Waring, P., Shanmugam, K., Gibbs, P. and Stein, U.
Annals of Oncology 28 (8): 1869-1875. 1 August 2017

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.
Juneja, M., Kobelt, D., Walther, W., Voss, C., Smith, J., Specker, E., Neuenschwander, M., Gohlke, B.O., Dahlmann, M., Radetzki, S., Preissner, R., von Kries, J.P., Schlag, P.M. and Stein, U.
PLoS Biology 15 (6): e2000784. 1 June 2017

Pancreatic cancer models for translational research.
Behrens, D., Walther, W. and Fichtner, I.
Pharmacology & Therapeutics 173 : 146-158. May 2017

Choosing wisely - Preclinical test models in the era of precision medicine.
Klinghammer, K., Walther, W. and Hoffmann, J.
Cancer Treatment Reviews 55 : 36-45. April 2017

Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression.
Mudduluru, G., Ilm, K., Fuchs, S. and Stein, U.
Oncotarget 8 (13): 21081-21094. 28 March 2017

Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy.
Pahle, J., Menzel, L., Niesler, N., Kobelt, D., Aumann, J., Rivera, M. and Walther, W.
BMC Cancer 17 (1): 129. 13 February 2017

Underlying mechanisms for distant metastasis - molecular biology.
Pachmayr, E., Treese, C. and Stein, U.
Visceral Medicine 33 (1): 11-20. February 2017

In vitro and in vivo investigations into the carbene gold chloride and thioglucoside anticancer drug candidates NHC-AuCl and NHC-AuSR.
Walther, W., Dada, O., O’Beirne, C., Ott, I., Sanchez-Sanz, G., Schmidt, C., Werner, C., Zhu, X. and Tacke, M.
Letters in Drug Design & Discovery 14 (2): 125-134. 2017

MACC1, a novel player in solid cancer carcinogenesis.
Mudduluru, G., Ilm, K., Dahlmann, M. and Stein, U.
In: Mechanisms of Molecular Carcinogenesis - Volume 1. Springer, Cham, 11-38. ISBN 978-3-319-53657-6 2017

2016

C/EBPβ regulates homeostatic and oncogenic gastric cell proliferation.
Regalo, G., Förster, S., Resende, C., Bauer, B., Fleige, B., Kemmner, W., Schlag, P.M., Meyer, T.F., Machado, J.C. and Leutz, A.
Journal of Molecular Medicine 94 (12): 1385-1395. December 2016

SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.
Schmid, F., Wang, Q., Huska, M.R., Andrade-Navarro, M.A., Lemm, M., Fichtner, I., Dahlmann, M., Kobelt, D., Walther, W., Smith, J., Schlag, P.M. and Stein, U.
Oncogene 35 (46): 5942-5952. 17 November 2016

Impact of anti-PEG IgM antibodies on the pharmacokinetics of pegylated asparaginase preparations in mice.
Poppenborg, S.M., Wittmann, J., Walther, W., Brandenburg, G., Kraehmer, R., Baumgart, J. and Leenders, F.
European Journal of Pharmaceutical Sciences 91 : 122-130. 25 August 2016

MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer.
Ilm, K., Fuchs, S., Mudduluru, G. and Stein, U.
Oncotarget 7 (33): 53443-53458. 16 August 2016

Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk.
Ashktorab, H., Hermann, P., Nouraie, M., Shokrani, B., Lee, E., Haidary, T., Brim, H. and Stein, U.
Journal of Translational Medicine 14 (1): 215. 20 July 2016

S100A4 in cancer metastasis: Wnt signaling-driven interventions for metastasis restriction.
Dahlmann, M., Kobelt, D., Walther, W., Mudduluru, G. and Stein, U.
Cancers 8 (6): 59. 20 June 2016

MACC1 induces tumor progression in transgenic mice and colorectal cancer patients via increased pluripotency markers Nanog and Oct4.
Lemos, C., Hardt, M.S., Juneja, M., Voss, C., Foerster, S., Jerchow, B., Haider, W., Blaker, H. and Stein, U.
Clinical Cancer Research 22 (11): 2812-2824. 1 June 2016

Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets.
Mudduluru, G., Walther, W., Kobelt, D., Dahlmann, M., Treese, C., Assaraf, Y.G. and Stein, U.
Drug Resistance Updates 26 : 10-27. May 2016

Vectors and strategies for nonviral cancer gene therapy.
Pahle, J. and Walther, W.
Expert Opinion on Biological Therapy 16 (4): 443-461. April 2016

Bacterial toxins for oncoleaking suicidal cancer gene therapy.
Pahle, J. and Walther, W.
Recent Results in Cancer Research 209 : 95-110. 2016

2015

Chemosensitization by diverging modulation by short-term and long-term TNF-α action on ABCB1 expression and NF-κB signaling in colon cancer.
Walther, W., Kobelt, D., Bauer, L., Aumann, J. and Stein, U.
International Journal of Oncology 47 (6): 2276-2285. December 2015

Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983.
Tanis, E., Julie, C., Emile, J.F., Mauer, M., Nordlinger, B., Aust, D., Roth, A., Lutz, M.P., Gruenberger, T., Wrba, F., Sorbye, H., Bechstein, W., Schlag, P., Fisseler, A. and Ruers, T.
European Journal of Cancer 51 (17): 2708-2717. November 2015

Structure-activity relationship study of dendritic polyglycerolamines for efficient siRNA transfection.
Mehrabadi, F.S., Hirsch, O., Zeisig, R., Posocco, P., Laurini, E., Pricl, S., Haag, R., Kemmner, W. and Calderon, M.
RSC Advances 5 (96): 78760-78770. 8 September 2015

Metastasis-associated in colon cancer 1 is an independent prognostic biomarker for survival in klatskin tumor patients.
Lederer, A., Herrmann, P., Seehofer, D., Dietel, M., Pratschke, J., Schlag, P. and Stein, U.
Hepatology 62 (3): 841-850. September 2015

RAGE mediates the pro-migratory response of extracellular S100A4 in human thyroid cancer cells.
Medapati, M.R., Dahlmann, M., Ghavami, S., Pathak, K.A., Lucman, L., Klonisch, T., Hoang-Vu, C., Stein, U. and Hombach-Klonisch, S.
Thyroid 25 (5): 514-527. 4 May 2015

Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study.
Koelzer, V.H., Herrmann, P., Zlobec, I., Karamitopoulou, E., Lugli, A. and Stein, U.
BMC Cancer 15 (1): 160. 21 March 2015

High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.
Ilm, K., Kemmner, W., Osterland, M., Burock, S., Koch, G., Herrmann, P., Schlag, P.M. and Stein, U.
Molecular Cancer 14 (1): 38. 14 February 2015

A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4.
Hansen, M.T., Forst, B., Cremers, N., Quagliata, L., Ambartsumian, N., Grum-Schwensen, B., Klingelhoefer, J., Abdul-Al, A., Herrmann, P., Osterland, M., Stein, U., Nielsen, G.H., Scherer, P.E., Lukanidin, E., Sleeman, J.P. and Grigorian, M.
Oncogene 34 (4): 424-435. 22 January 2015

Circulating metastasis associated in colon cancer 1 transcripts in gastric cancer patient plasma as diagnostic and prognostic biomarker.
Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Stein, U.
World Journal of Gastroenterology 21 (1): 333-341. 7 January 2015

Oncoleaking: use of the pore-forming clostridium perfringens enterotoxin (CPE) for suicide gene therapy.
Pahle, J., Aumann, J., Kobelt, D. and Walther, W.
Methods in Molecular Biology 1317 : 69-85. 2015

RNA interference for antimetastatic therapy.
Dahlmann, M. and Stein, U.
Methods in Molecular Biology 1317 : 153-165. 2015

2014

Mouse models of human cancer.
Böck, B.C., Stein, U., Schmitt, C.A. and Augustin, H.G.
Cancer Research 74 (17): 4671-4675. 1 September 2014

In vitro and in vivo investigations into the carbene copper bromide anticancer drug candidate WBC4.
Walther, W., Fichtner, I., Hackenberg, F., Streciwilk, W. and Tacke, M.
Letters in Drug Design & Discovery 11 (7): 825-832. August 2014

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.
Wikman, H., Westphal, L., Schmid, F., Pollari, S., Kropidlowski, J., Sielaff-Frimpong, B., Glatzel, M., Matschke, J., Westphal, M., Iljin, K., Huhtala, H., Terracciano, L., Kallioniemi, A., Sauter, G., Mueller, V., Witzel, I., Lamszus, K., Kemming, D. and Pantel, K.
Oncotarget 5 (10): 3076-3087. 30 May 2014

RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.
Dahlmann, M., Okhrimenko, A., Marcinkowski, P., Osterland, M., Herrmann, P., Smith, J., Heizmann, C.W., Schlag, P.M. and Stein, U.
Oncotarget 5 (10): 3220-3233. 30 May 2014

Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector.
Kobelt, D., Aumann, J., Schmidt, M., Wittig, B., Fichtner, I., Behrens, D., Lemm, M., Freundt, G., Schlag, P.M. and Walther, W.
Molecular Oncology 8 (3): 609-619. May 2014

Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma.
Fehlker, M., Huska, M.R., Joens, T., Andrade-Navarro, M.A. and Kemmner, W.
BMC Cancer 14 (1): 64. 5 February 2014

Redundant human omentum fat: A leap towards regenerative medicine.
lndumathi, S., Harikrishnan, R. and Dhanasekaran, M.
In: Regenerative Medicine. Springer, 125-133. ISBN 978-1-4471-6541-5 2014

Subcutaneous adipose tissue-derived stem cells: advancement and applications in regenerative medicine.
lndumathi, S., Mishra, R., Harikrishnan, R. and Dhanasekaran, M.
In: Regenerative Medicine. Springer, 91-112. ISBN 978-1-4471-6541-5 2014

2013

A seven-year storage report of good manufacturing practice-grade naked plasmid DNA: stability, topology, and in vitro/in vivo functional analysis.
Walther, W., Schmeer, M., Kobelt, D., Baier, R., Harder, A., Walhorn, V., Anselmetti, D., Aumann, J., Fichtner, I. and Schleef, M.
Human Gene Therapy Clinical Development 24 (4): 147-153. December 2013

Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis.
Hagemann, C., Fuchs, S., Monoranu, C.M., Herrmann, P., Smith, J., Hohmann, T., Grabiec, U., Kessler, A.F., Dehghani, F., Loehr, M., Ernestus, R.I., Vince, G.H. and Stein, U.
Neuro-Oncology 15 (12): 1696-1709. December 2013

Klinische und epidemiologische Krebsregister : Krebsregister in Deutschland – quo vadis? [Clinical and epidemiological Cancer Registers Cancer Registers in Germany - quo vadis?].
Moeslein, G., Haier, J. and Schlag, P.M.
Onkologe 19 (12): 1022-1024. December 2013

Current status of gene therapy for cancer.
Walther, W. and Schlag, P.M.
Current Opinion in Oncology 25 (6): 659-664. November 2013

Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial.
Nordlinger, B., Sorbye, H., Glimelius, B., Poston, G.J., Schlag, P.M., Rougier, P., Bechstein, W.O., Primrose, J.N., Walpole, E.T., Finch-Jones, M., Jaeck, D., Mirza, D., Parks, R.W., Mauer, M., Tanis, E., Van Cutsem, E., Scheithauer, W. and Gruenberger, T.
Lancet Oncology 14 (12): 1208-1215. November 2013

Paul Ehrlichs "magic bullets" [Paul Ehrlichs "magic bullets"].
Hochhaus, A., Schlag, P.M., Cordes, N. and Hoeffken, K.
Onkologe 19 (10): 806-808. October 2013

Promoter identification and transcriptional regulation of the metastasis gene MACC1 in colorectal cancer.
Juneja, M., Ilm, K., Schlag, P.M. and Stein, U.
Molecular Oncology 7 (5): 929-943. October 2013

Rolle und Aufgaben der chirurgischen Onkologie im Rahmen molekular definierter Therapien [Role and function of surgical oncology in molecular defined therapy].
Gaedcke, J., Schlag, P.M. and Ghadimi, M.
Onkologe 19 (10): 858-862. October 2013

MACC1 - a novel target for solid cancers.
Stein, U.
Expert Opinion on Therapeutic Targets 17 (9): 1039-1052. September 2013

The activity of titanocene T against xenografted Caki-1 tumors.
Walther, W., Fichtner, I., Deally, A., Hogan, M. and Tacke, M.
Letters in Drug Design & Discovery 10 (5): 375-381. June 2013

New medical technologies of the future.
Graschew, G., Rakowsky, S., Roelofs, T.A. and Schlag, P.M.
In: 2013 International Conference on Digital Technologies (DT), 29-31 May 2013, Zilina, Slovakia. 29 May 2013

Vom "Stiefkind" zum Paradebeispiel [From "stepchild" to classic example].
Al-Batran, S.E. and Schlag, P.M.
Onkologe 19 (5): 350. May 2013

Minicircle-based vectors for nonviral gene therapy: in vitro characterization and in vivo application.
Kobelt, D., Aumann, J., Schleef, M., Schmeer, M., Stein, U., Schlag, P.M. and Walther, W.
In: Minicircle and miniplasmid DNA vectors: the future of nonviral and viral gene transfer. Wiley, 177-188. ISBN 978-3-527-32456-9 17 April 2013

Wenn Symptome im Vordergrund stehen [When Symptoms are paramount].
Adamietz, I. A. and Schlag, P. M.
Onkologe 19 (4): 262-264. April 2013

Wdr66 is a novel marker for risk stratification and involved in epithelial-mesenchymal transition of esophageal squamous cell carcinoma.
Wang, Q., Ma, C. and Kemmner, W.
BMC Cancer 13 (1): 137. 21 March 2013

Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells.
Grabundzija, I., Wang, J., Sebe, A., Erdei, Z., Kajdi, R., Devaraj, A., Steinemann, D., Szuhai, K., Stein, U., Cantz, T., Schambach, A., Baum, C., Izsvák, Z., Sarkadi, B. and Ivics, Z.
Nucleic Acids Research 41 (3): 1829-1847. 1 February 2013

Anti-metastatic treatment in colorectal cancer: targeting signaling pathways.
Lemos, C., Sack, U., Schmid, F., Juneja, M. and Stein, U.
Current Pharmaceutical Design 19 (5): 841-863. February 2013

Microarray meta-analysis defines global angiogenesis-related gene expression signatures in human carcinomas.
Anders, M., Fehlker, M., Wang, Q., Wissmann, C., Pilarsky, C., Kemmner, W. and Hoecker, M.
Molecular Carcinogenesis 52 (1): 29-38. January 2013

Performance of high quality minicircle DNA for in vitro and in vivo gene transfer.
Kobelt, D., Schleef, M., Schmeer, M., Aumann, J., Schlag, P.M. and Walther, W.
Molecular Biotechnology 53 (1): 80-89. January 2013

2012

HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: gene gun is superior to jet injector in inducing CTL responses and protective immunity.
Nguyen-Hoai, T., Kobelt, D., Hohn, O., Vu, M.D., Schlag, P.M., Doerken, B., Norley, S., Lipp, M., Walther, W., Pezzutto, A. and Westermann, J.
OncoImmunology 1 (9): 1537-1545. 1 December 2012

Circulating MACC1 transcripts in colorectal cancer patient plasma predict metastasis and prognosis.
Stein, U., Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Schlag, P.M.
PLoS ONE 7 (11): e49249. 14 November 2012

Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer.
Nitsche, U., Rosenberg, R., Balmert, A., Schuster, T., Slotta-Huspenina, J., Herrmann, P., Bader, F.G., Friess, H., Schlag, P.M., Stein, U. and Janssen, K.P.
Annals of Surgery 256 (5): 763-771. November 2012

Cardiovascular medications in angiogenesis- how to avoid the sting in the tail.
Ma, C., Wang, Q., Man, Y. and Kemmner, W.
International Journal of Cancer 131 (6): 1249-1259. 15 September 2012

Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.
Dahlmann, M., Sack, U., Herrmann, P., Lemm, M., Fichtner, I., Schlag, P.M. and Stein, U.
Oncotarget 3 (8): 783-797. 7 August 2012

In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.
Pichorner, A., Sack, U., Kobelt, D., Kelch, I., Arlt, F., Smith, J., Walther, W., Schlag, P.M. and Stein, U.
Clinical and Experimental Metastasis 29 (6): 573-583. August 2012

Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer.
Galling, N., Kobelt, D., Aumann, J., Schmidt, M., Wittig, B., Schlag, P.M. and Walther, W.
Human Gene Therapy Part B Methods 23 (4): 264-270. August 2012

The immediate early gene Ier2 promotes tumor cell motility and metastasis, and predicts poor survival of colorectal cancer patients.
Neeb, A., Wallbaum, S., Novac, N., Dukovic-Schulze, S., Scholl, I., Schreiber, C., Schlag, P., Moll, J., Stein, U. and Sleeman, J.P.
Oncogene 31 (33): 3796-3806. August 2012

SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer.
Schmid, F., Burock, S., Klockmeier, K., Schlag, P.M. and Stein, U.
Molecular Cancer 11 (1): 49. 29 July 2012

Primary malignant tumors of the liver.
Settmacher, U. and Schlag, P.M.
Onkologe 18 (7): 570-572. July 2012

Thiamine is a substrate of organic cation transporters in Caco-2 cells.
Lemos, C., Faria, A., Meireles, M., Martel, F., Monteiro, R. and Calhau, C.
European Journal of Pharmacology 682 (1-3): 37-42. 5 May 2012

In-vivo tumor imaging using a novel RNAi-based detection mechanism.
Wan, K., Ebert, B., Voigt, J., Wang, Q., Dai, Y., Haag, R. and Kemmner, W.
Nanomedicine 8 (4): 393-398. May 2012

Interdisziplinaere Tumorkonferenzen : regionale und ueberregionale telemedizinische und teleradiologische Anbindung von Tumorzentren [Interdisciplinary tumor boards : regional and supraregional telemedical and teleradiological links to tumor boards].
Guettler, F.V., Rakowsky, S., Nagel, S.N., Teichgraeber, U. and Schlag, P.M.
Onkologe 18 (5): 389-397. May 2012

Kommunikationstechnologie, Telematik und Robotik : Spagat zwischen Vision und Realitaet [Communication technology, telematics and robotics : balance between vision and reality].
Feussner, H. and Schlag, P.M.
Onkologe 18 (5): 386-388. May 2012

Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors.
Walther, W., Petkov, S., Kuvardina, O.N., Aumann, J., Kobelt, D., Fichtner, I., Lemm, M., Piontek, J., Blasig, I.E., Stein, U. and Schlag, P.M.
Gene Therapy 19 (5): 494-503. May 2012

Detection of circulating tumor-associated antigen depends on the domains recognized by the monoclonal antibodies used: N-terminal trimmed EpCAM-levels are much higher than untrimmed forms.
Schmetzer, O., Moldenhauer, G., Nicolaou, A., Schlag, P., Riesenberg, R. and Pezzutto, A.
Immunology Letters 143 (2): 184-192. 30 April 2012

Impact of mutant beta-catenin on ABCB1 expression and therapy response in colon cancer cells.
Stein, U., Fleuter, C., Siegel, F., Smith, J., Kopacek, A., Scudiero, D.A., Hite, K.M., Schlag, P.M., Shoemaker, R.H. and Walther, W.
British Journal of Cancer 106 (8): 1395-1405. 10 April 2012

Predictive factors for the benefit of perioperative FOLFOX for resectable liver metastasis in colorectal cancer patients (EORTC Intergroup trial 40983).
Sorbye, H., Mauer, M., Gruenberger, T., Glimelius, B., Poston, G.J., Schlag, P.M., Rougier, P., Bechstein, W.O., Primrose, J.N., Walpole, E.T., Finch-Jones, M., Jaeck, D., Mirza, D., Parks, R.W., Collette, L., Cutsem, E.V., Scheithauer, W., Lutz, M.P. and Nordlinger, B.
Annals of Surgery 255 (3): 534-539. March 2012

Loss of UDP-N-acetylglucosamine 2-epimerase/ N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells.
Kemmner, W., Kessel, P., Sanchez-Ruderisch, H., Moeller, H., Hinderlich, S., Schlag, P.M. and Detjen, K.
FASEB Journal 26 (2): 938-946. February 2012

Versorgungsforschung – Notwendigkeit und Chancen [Health service research - necessity and opportunity].
Schmitz, S. and Schlag, P.M.
Onkologe 18 (2): 102-104. February 2012

The liberation of women from the scourge of cervical cancer.
Schneider, A. and Schlag, P.M.
Onkologe 18 (1): 6-8. January 2012

Praeklinische Validierung fuer das US-gestuetzte Navigationssystem Liver Track.
Eulenstein, S., Jentsch, M. and Schlag, P.M.
In: Annual Meeting on CURAC (Computer- und Roboterassistierte Chirurgie), 15 Nov 2012, Duesseldorf. 2012

2011

Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas.
Kretschmer, C., Conradi, A., Kemmner, W. and Sterner-Kock, A.
Cellular Oncology 34 (5): 419-434. 6 October 2011

THBS4, a novel stromal molecule of diffuse-type gastric adenocarcinomas, identified by transcriptome-wide expression profiling.
Foerster, S., Gretschel, S., Joens, T., Yashiro, M. and Kemmner, W.
Modern Pathology 24 (10): 1390-1403. October 2011

Discovery of a novel tumour metastasis-promoting gene, NVM-1.
Thiele, W., Novac, N., Mink, S., Schreiber, C., Plaumann, D., Fritzmann, J., Cremers, N., Rothley, M., Schwager, C., Regiert, T., Huber, P.E., Stein, U., Schlag, P., Moll, J., Abdollahi, A. and Sleeman, J.P.
Journal of Pathology 225 (1): 96-105. September 2011

S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells.
Sack, U., Walther, W., Scudiero, D., Selby, M., Aumann, J., Lemos, C., Fichtner, I., Schlag, P.M., Shoemaker, R.H. and Stein, U.
Molecular Biology of the Cell 22 (18): 3344-3354. September 2011

The impact of short-term psycho-oncological interventions on the psychological outcome of cancer patients of a surgical-oncology department - A randomised controlled study.
Goerling, U., Foerg, A., Sander, S., Schramm, N. and Schlag, P.M.
European Journal of Cancer 47 (13): 2009-2014. September 2011

Novel effect of antihelminthic niclosamide on S100A4-mediated metastatic progression in colon cancer.
Sack, U., Walther, W., Scudiero, D., Selby, M., Kobelt, D., Lemm, M., Fichtner, I., Schlag, P.M., Shoemaker, R.H. and Stein, U.
Journal of the National Cancer Institute 103 (13): 1018-1036. 6 July 2011

„Deep sequencing“ und praediktive Modellierung als Konzept therapeutischer Entscheidungsfindungen in der Onkologie [Deep sequencing and predictive modeling as a concept for therapeutic decision-making in oncology].
Lehrach, H., Schaefer, R. and Schlag, P. M.
Onkologe 17 (6): 477-486. June 2011

Transcriptomics and cancer risk assessment.
Kemmner, W.
In: Cancer risk evaluation : methods and trends. Wiley-VCH, Weinheim, 195-205. ISBN 9783527327539 27 April 2011

S3-Leitlinie "Magenkarzinom" - Diagnostik und Therapie der Adenokarzinome des Magens und oesophagogastralen Uebergangs (AWMF-Regist.-Nr. 032-009-OL) [German S3-Guideline "Diagnosis and Treatment of Esophagogastric Cancer"].
Moehler, M., Al-Batran, S.E., Andus, T., Anthuber, M., Arends, J., Arnold, D., Aust, D., Baier, P., Baretton, G., Bernhardt, J., Boeing, H., Boehle, E., Bokemeyer, C., Bornschein, J., Budach, W., Burmester, E., Caca, K., Diemer, W.A., Dietrich, C.F., Ebert, M., Eickhoff, A., Ell, C., Fahlke, J., Feußner, H., Fietkau, R., Fischbach, W., Fleig, W., Flentje, M., Gabbert, H.E., Galle, P.R., Geissler, M., Gockel, I., Graeven, U., Grenacher, L., Gross, S., Hartmann, J.T., Heike, M., Heinemann, V., Herbst, B., Herrmann, T., Hoecht, S., Hofheinz, R.D., Hoefler, H., Hoehler, T., Hoelscher, A.H., Horneber, M., Huebner, J., Izbicki, J.R., Jakobs, R., Jenssen, C., Kanzler, S., Keller, M., Kiesslich, R., Klautke, G., Körber, J., Krause, B.J., Kuhn, C., Kullmann, F., Lang, H., Link, H., Lordick, F., Ludwig, K., Lutz, M., Mahlberg, R., Malfertheiner, P., Merkel, S., Messmann, H., Meyer, H.J., Moenig, S., Piso, P., Pistorius, S., Porschen, R., Rabenstein, T., Reichardt, P., Ridwelski, K., Roecken, C., Roetzer, I., Rohr, P., Schepp, W., Schlag, P.M., Schmid, R.M., Schmidberger, H., Schmiegel, W.H., Schmoll, H.J., Schuch, G., Schuhmacher, C., Schuette, K., Schwenk, W., Selgrad, M., Sendler, A., Seraphin, J., Seufferlein, T., Stahl, M., Stein, H., Stoll, C., Stuschke, M., Tannapfel, A., Tholen, R., Thuss-Patience, P., Treml, K., Vanhoefer, U., Vieth, M., Vogelsang, H., Wagner, D., Wedding, U., Weimann, A., Wilke, H. and Wittekind, C.
Zeitschrift fuer Gastroenterologie 49 (4): 461-531. April 2011

Automatic calibration of 3D ultrasound probes.
Lange, T., Kraft, S., Eulenstein, S., Lamecker, H. and Schlag, P.M.
In: Workshops Bildverarbeitung fur die Medizin: Algorithmen - Systeme - Anwendungen, BVM 2011, 20-22 Mar 2011, Luebeck, Germany. 13 March 2011

Diagnostic and prognostic value of metastasis inducer S100A4 transcripts in plasma of colon, rectal, and gastric cancer patients.
Stein, U., Burock, S., Herrmann, P., Wendler, I., Niederstrasser, M., Wernecke, K.D. and Schlag, P.M.
Journal of Molecular Diagnostics 13 (2): 189-198. March 2011

Integrated microfluidic platform for the electrochemical detection of breast cancer markers in patient serum samples.
Fragoso, A., Latta, D., Laboria, N., von Germar, F., Hansen-Hagge, T.E., Kemmner, W., Gaertner, C., Klemm, R., Drese, K.S. and O'Sullivan, C.K.
Lab on a Chip 11 (4): 625-631. 21 February 2011

Identification of early molecular markers for breast cancer.
Kretschmer, C., Sterner-Kock, A., Siedentopf, F., Schoenegg, W., Schlag, P.M. and Kemmner, W.
Molecular Cancer 10 (1): 15. 11 February 2011

A multichannel time-domain scanning fluorescence mammograph: Performance assessment and first in vivo results.
Grosenick, D., Hagen, A., Steinkellner, O., Poellinger, A., Burock, S., Schlag, P.M., Rinneberg, H. and Macdonald, R.
Review of Scientific Instruments 82 (2): 1024302. February 2011

Breast cancer: early- and late-fluorescence near-infrared imaging with indocyanine green a preliminary study.
Poellinger, A., Burock, S., Grosenick, D., Hagen, A., Luedemann, L., Diekmann, F., Engelken, F., Macdonald, R., Rinneberg, H. and Schlag, P.M.
Radiology 258 (2): 409-416. February 2011

Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis.
Stein, U., Arlt, F., Smith, J., Sack, U., Herrmann, P., Walther, W., Lemm, M., Fichtner, I., Shoemaker, R.H. and Schlag, P.M.
Neoplasia 13 (2): 131-144. February 2011

2010

Neoadjuvant chemotherapy compared with surgery alone for locally advanced cancer of the stomach and cardia: European Organisation for Research and Treatment of Cancer Randomized Trial 40954.
Schuhmacher, C., Gretschel, S., Lordick, F., Reichardt, P., Hohenberger, W., Eisenberger, C.F., Haag, C., Mauer, M.E., Hasan, B., Welch, J., Ott, K., Hoelscher, A., Schneider, P.M., Bechstein, W., Wilke, H., Lutz, M.P., Nordlinger, B., Van Cutsem, E., Siewert, J.R. and Schlag, P.M.
Journal of Clinical Oncology 28 (35): 5210-5218. 10 December 2010

Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Juerchott, K., Kuban, R.J., Krech, T., Blüthgen, N., Stein, U., Walther, W., Friese, C., Kielbasa, S.M., Ungethuem, U., Lund, P., Knoesel, T., Kemmner, W., Morkel, M., Fritzmann, J., Schlag, P.M., Birchmeier, W., Krueger, T., Sperling, S., Sers, C., Royer, H.D., Herzel, H. and Schaefer, R.
PLoS Genetics 6 (12): e1001231. 2 December 2010

De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway.
Fritsche-Guenther, R., Noske, A., Ungethuem, U., Kuban, R.J., Schlag, P.M., Tunn, P.U., Karle, J., Krenn, V., Dietel, M. and Sers, C.
Histopathology 57 (6): 836-850. December 2010

Therapeutic potential of CAMPATH-1H in skeletal tumours.
Fritsche-Guenther, R., Gruetzkau, A., Noske, A., Melcher, I., Schaser, K.D., Schlag, P.M., Kasper, H.U., Krenn, V. and Sers, C.
Histopathology 57 (6): 851-861. December 2010

Integration der Hyperthermie in chirurgisch-onkologische Techniken [Integration of hyperthermia into surgical oncological techniques].
Burock, S. and Schlag, P.M.
Onkologe 16 (11): 1079-1085. November 2010

Zwischen Hoffen und Bangen [Between hope and fear].
Schlag, P.M. and Bamberg, M.
Onkologe 16 (11): 11038-1040. November 2010

Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: biphasic heat induction of cytosine deaminase suicide gene expression.
Kobelt, D., Aumann, J., Fichtner, I., Stein, U., Schlag, P.M. and Walther, W.
Molecular Biotechnology 46 (2): 197-205. October 2010

Gallengangskarzinom - Fortschritte und Grenzverschiebungen[Cholangiocarcinoma - Progress and shifting boundaries].
Jonas, S. and Schlag, P.M.
Onkologe 16 (9): 840. September 2010

Practice and effectiveness of outpatient psycho-oncological counseling for cancer patients.
Goerling, U., Tagmat, D., Muffler, E., Schramm, N., Wernecke, K.D. and Schlag, P.M.
Journal of Cancer 1 : 112-119. 23 August 2010

Rektumkarzinom - ein Musterbeispiel fuer Interdisziplinaritaet [Rectal carcinoma - a classic example of interdisciplinarity].
Roedel, C. and Schlag, P.M.
Onkologe 16 (8): 738-740. August 2010

Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
Kumpf, O., Giamarellos-Bourboulis, E.J., Koch, A., Hamann, L., Mouktaroudi, M., Oh, D.Y., Latz, E., Lorenz, E., Schwartz, D.A., Ferwerda, B., Routsi, C., Skalioti, C., Kullberg, B.J., van der Meer, J.W., Schlag, P.M., Netea, M.G., Zacharowski, K. and Schumann, R.R.
Critical Care 14 (3): R103. 3 June 2010

Pankreaskarzinom - auf der therapeutischen Wartebank [Pancreatic cancer - on the therapeutic waiting bench].
Hopt, U. and Schlag, P.M.
Onkologe 16 (6): 555-556. June 2010

ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Mueller, T., Stein, U., Poletti, A., Garzia, L., Rothley, M., Plaumann, D., Thiele, W., Bauer, M., Galasso, A., Schlag, P., Pankratz, M., Zollo, M. and Sleeman, J.P.
Oncogene 29 (16): 2393-2403. 22 April 2010

Amperometric immunosensor for carcinoembryonic antigen in colon cancer samples based on monolayers of dendritic bipodal scaffolds.
Laboria, N., Fragoso, A., Kemmner, W., Latta, D., Nilsson, O., Luz Botero, M., Drese, K. and O'Sullivan, C.K.
Analytical Chemistry 82 (5): 1712-1719. 1 March 2010

Authors' reply: Treatment of oesophageal anastomotic leaks by temporary stenting with self-expanding plastic stents (Br J Surg 2009; 96: 887-891).
Dai, Y.Y., Gretschel, S., Dudeck, O., Rau, B., Schlag, P.M. and Huenerbein, M.
British Journal of Surgery 97 (2): 294-295. February 2010

Viel Bewegung in der interdisziplinaeren Therapie des Nierenzellkarzinoms [A lot of movement in the interdisciplinary treatment of renal cell carcinoma].
Wiegel, T. and Schlag, P.M.
Onkologe 16 (2): 119-120. February 2010

MACC1 - more than metastasis? Facts and predictions about a novel gene.
Stein, U., Dahlmann, M. and Walther, W.
Journal of Molecular Medicine 88 (1): 11-18. January 2010

Current status of sentinel lymph node biopsy in adenocarcinoma of the distal esophagus, gastric cardia, and proximal stomach.
Gretschel, S. and Schlag, P.M.
Recent Results in Cancer Research 182 : 107-114. 2010

Jet-injection of short hairpin RNA-encoding vectors into tumor cells.
Walther, W., Stein, U. and Lage, H.
Methods in Molecular Biology 629 : 123-139. 2010

2009

Colon cancer metastasis: MACC1 and Met as metastatic pacemakers.
Arlt, F. and Stein, U.
International Journal of Biochemistry and Cell Biology 41 (12): 2356-2359. December 2009

Kolonkarzinom – Es bleibt noch viel zu tun [Colorectal carcinoma - there is still a lot to be done].
Weitz, J. and Schlag, P.M.
Onkologe 15 (12): 1179. December 2009

Wnt up your mind - intervention strategies for S100A4-induced metastasis in colon cancer.
Sack, U. and Stein, U.
General Physiology and Biophysics 28 (Focus Iss): F55-F64. December 2009

"Curt Meyer-Gedaechtnispreis" Forschungspreis der Berliner Krebsgesellschaft 2010 ausgeschrieben.
Schlag, P.M.
Onkologe 15 (11): 1100. November 2009

Regionale Verbuende in der Onkologie. Von der Idee zur Gemeinschaft [Regional associations in oncology. From the concept to a community].
Zuenkeler, M. and Schlag, P.M.
Onkologe 15 (11): 1070-1077. November 2009

Late-fluorescence mammography assesses tumor capillary permeability and differentiates malignant from benign lesions.
Hagen, A., Grosenick, D., Macdonald, R., Rinneberg, H., Burock, S., Warnick, P., Poellinger, A. and Schlag, P.M.
Optics Express 17 (19): 17016-17033. 14 September 2009

MACC1 controls Met: What a difference an Sp1 site makes.
Stein, U., Smith, J., Walther, W. and Arlt, F.
Cell Cycle 8 (15): 2467-2469. 1 August 2009

Operative Therapie des malignen Melanoms [Operative treatment of malignant melanomas].
Schneider-Burrus, S., Drecoll, U. and Schlag, P.M.
Onkologe 15 (8): 750-757. August 2009

Sentinel node biopsy for the individualization of surgical strategy for cure of early-stage colon cancer.
Cahill, R.A., Bembenek, A., Sirop, S., Waterhouse, D.F., Schneider, W., Leroy, J., Wiese, D., Beutler, T., Bilchik, A., Saha, S. and Schlag, P.M.
Annals of Surgical Oncology 16 (8): 2170-2180. August 2009

Translationale Melanomforschung ist nach wie vor schwer in praktische Erfolge umzumuenzen [Translational melamoma research remains difficult to transform into practical success].
Kleeberg, U.R. and Schlag, P.M.
Onkologe 15 (8): 735-736. August 2009

Treatment of oesophageal anastomotic leaks by temporary stenting with self-expanding plastic stents.
Dai, Y.Y., Gretschel, S., Dudeck, O., Rau, B., Schlag, P.M. and Huenerbein, M.
British Journal of Surgery 96 (8): 887-891. August 2009

Heat-responsive gene expression for gene therapy.
Walther, W. and Stein, U.
Advanced Drug Delivery Reviews 61 (7-8): 641-649. 2 July 2009

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Fritzmann, J., Morkel, M., Besser, D., Budczies, J., Kosel, F., Brembeck, F.H., Stein, U., Fichtner, I., Schlag, P.M. and Birchmeier, W.
Gastroenterology 137 (11): 165-175. July 2009

Tranplantation und Onkologie [Transplantation and oncology].
Settmacher, U. and Schlag, P.M.
Onkologe 15 (6): 555-556. June 2009

Bildgebende Verfahren in der Primaer- und Rezidivdiagnostik [Imaging procedures for primary and recurrent diagnostics].
Schlag, P.M., Dresel, S. and Gebauer, B.
Onkologe 15 (5): 487-495. May 2009

Identification of brain- and bone-specific breast cancer metastasis genes.
Klein, A., Olendrowitz, C., Schmutzler, R., Hampl, J., Schlag, P.M., Maass, N., Arnold, N., Wessel, R., Ramser, J., Meindl, A., Scherneck, S. and Seitz, S.
Cancer Letters 276 (2): 212-220. 18 April 2009

Weichteilsarkome [Soft part arkome].
Schuette, J. and Schlag, P.M.
Onkologe 15 (4): 351. April 2009

Experimental comparison of landmark-based methods for 3D elastic registration of pre- and postoperative liver CT data.
Lange, T., Woerz, S., Rohr, K. and Schlag, P.M.
In: Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, 07 Febr 2009, Lake Buena Vista, Florida, USA. 13 March 2009

HIF-1alpha determines the metastatic potential of gastric cancer cells.
Rohwer, N., Lobitz, S., Daskalow, K., Joens, T., Vieth, M., Schlag, P.M., Kemmner, W., Wiedenmann, B., Cramer, T. and Hoecker, M.
British Journal of Cancer 100 (5): 772-781. 10 March 2009

Peritoneales Mesotheliom – ein seltener Tumor der Bauchhoehle [Peritoneal mesothelioma - rare abdominal tumors].
Tannapfel, A., Bruecher, B. and Schlag, P.M.
Onkologe 15 (3): 250-260. March 2009

Seltene Tumoren - Vom Seltenen zum Generellen [Rare tumours - From rare to general].
Schlag, P.M., Bamberg, M. and Hoeffken, K.
Onkologe 15 (3): 209-210. March 2009

Upgrade of an optical navigation system with a permanent electromagnetic position control : A first step towards "navigated control" for liver surgery.
Beller, S., Eulenstein, S., Lange, T., Huenerbein, M. and Schlag, P.M.
Journal of Hepato-Biliary-Pancreatic Surgery 16 (2): 165-170. March 2009

Preoperative short-course radiotherapy versus combined radiochemotherapy in locally advanced rectal cancer: a multi-centre prospectively randomised study of the Berlin Cancer Society.
Siegel, R., Burock, S., Wernecke, K.D., Kretzschmar, A., Dietel, M., Loy, V., Koswig, S., Budach, V. and Schlag, P.M.
BMC Cancer 9 (1): 50. 6 February 2009

Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression.
Anders, M., Vieth, M., Roecken, C., Ebert, M., Pross, M., Gretschel, S., Schlag, P.M., Wiedenmann, B., Kemmner, W. and Hoecker, M.
British Journal of Cancer 100 (2): 352-359. 27 January 2009

3D ultrasound-CT registration of the liver using combined landmark-intensity information.
Lange, T., Papenberg, N., Heldmann, S., Modersitzki, J., Fischer, B., Lamecker, H. and Schlag, P.M.
International Journal of Computer Assisted Radiology and Surgery 4 (1): 79-88. January 2009

A new measure to assess the difficulty of liver resection.
Beller, S., Eulenstein, S., Lange, T., Niederstrasser, M., Huenerbein, M. and Schlag, P.M.
European Journal of Surgical Oncology 35 (1): 59-64. January 2009

Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tumor cells in colorectal cancer patients following resection of liver metastases: results of a prospective randomized trial.
Schulze, T., Kemmner, W., Weitz, J., Wernecke, K.D., Schirrmacher, V. and Schlag, P.M.
Cancer Immunology Immunotherapy 58 (1): 61-69. January 2009

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Stein, U., Walther, W., Arlt, F., Schwabe, H., Smith, J., Fichtner, I., Birchmeier, W. and Schlag, P.M.
Nature Medicine 15 (1): 59-67. January 2009

Why we don't do, what we know?
Hoeffken, K., Bamberg, M. and Schlag, P.M.
Onkologe 15 (1): 84. January 2009

Ductoscopy of intraductal neoplasia of the breast.
Huenerbein, M., Raubach, M., Dai, K. and Schlag, P.M.
In: Minimally Invasive Breast Biopsies. Recent Results in Cancer Research, 173 . Springer, Berlin, 129-136. ISBN 978-3-540-31403-5 2009

Exploiting scientific workflows for large-scale gene expression data analysis.
de Stasio, A., Ertelt, M., Kemmner, W., Leser, U. and Ceccarelli, M.
In: 24th International Symposium on Computer and Information Sciences, ISCIS 2009, 14-16 Sept 2009, Guzelyurt . 2009

Landmark constrained non-parametric image registration with isotropic tolerances.
Papenberg, N., Olesch, J., Lange, T., Schlag, P.M. and Fischer, B.
Informatik aktuell : 122-126. 2009

Landmark constrained non-rigid image registration with anisotropic tolerances.
Lange, T., Papenberg, N., Olesch, J., Fischer, B. and Schlag, P.M.
IFMBE Proceedings 25 (4): 2238-2241. 2009

Landmark-based 3D elastic registration of pre- and postoperative liver CT data: An experimental comparison.
Lange, T., Woerz, S., Rohr, K. and Schlag, P.M.
Informatik aktuell : 107-111. 2009

Nonviral jet-injection technology for intratumoral in vivo gene transfer of naked DNA.
Walther, W., Fichtner, I., Schlag, P.M. and Stein, U.S.
Methods in Molecular Biology 542 : 195-208. 2009

The human transcriptome: implications for the understanding of human disease.
Schaefer, R., Kemmner, W. and Sers, C.
In: Molecular pathology: the molecular basis of human disease. Elsevier, Academic Press, Amsterdam, 123-149. ISBN 978-0-12-374419-7 2009

2008

Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay.
Gruetzmann, R., Molnar, B., Pilarsky, C., Habermann, J.K., Schlag, P.M., Saeger, H.D., Miehlke, S., Stolz, T., Model, F., Roblick, U.J., Bruch, H.P., Koch, R., Liebenberg, V., Devos, T., Song, X., Day, R.H., Sledziewski, A.Z. and Lofton-Day, C.
PLoS ONE 3 (11): e3759. 19 November 2008

Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer.
Walther, W., Siegel, R., Kobelt, D., Knoesel, T., Dietel, M., Bembenek, A., Aumann, J., Schleef, M., Baier, R., Stein, U. and Schlag, P.M.
Clinical Cancer Research 14 (22): 7545-7553. 15 November 2008

Multimodale Therapie des Rektumkarzinoms [Multimodality treatment for colorectal cancer].
Roedel, C., Hoehler, T., Sauer, R., Siewczynski, R., Flentje, M., Budach, V. and Schlag, P.M.
Onkologie 31 (Suppl 5): 24-28. November 2008

Therapie des Magenkarzinoms [Treatment of gastric cancer].
Lordick, F., Ridwelski, K., Al-Batran, S.E., Trarbach, T., Schlag, P.M. and Piso, P.
Onkologie 31 (Suppl 5): 32-39. November 2008

SV40 large T antigen-transformed human primary normal and cancerous mammary epithelial cells are phenotypically similar but can be distinguished in 3D culture with selection medium.
Li, L.P., Willimsky, G., Seitz, S., Xu, Y., Li, Y., Schwarz, L.E., Schlag, P.M. and Blankenstein, T.
International Journal of Cancer 123 (7): 1516-1525. 1 October 2008

Nierenzellkarzinom – Neues zu Diagnostik und Therapie? [Renal cell carcinoma - Anything new in diagnosis and therapy?].
Heinzer, H. and Schlag, P.M.
Onkologe 14 (10): 991. October 2008

Technique and clinical consequences of sentinel lymph node biopsy in colorectal cancer.
Bembenek, A., String, A., Gretschel, S. and Schlag, P.M.
Surgical Oncology 17 (3): 183-193. September 2008

The CUP-Syndrome - A quintessential challenge on interdisciplinary approach in oncology.
Flentje, M. and Schlag, P.M.
Onkologe 14 (9): 859. September 2008

Lymphatic mapping and sentinel lymph node biopsy in epidermoid carcinoma of the anal canal.
Gretschel, S., Warnick, P., Bembenek, A., Dresel, S., Koswig, S., String, A., Huenerbein, M. and Schlag, P.M.
European Journal of Surgical Oncology 34 (8): 890-894. August 2008

The location of small tumor deposits in the SLN predicts Non-SLN macrometastases in breast cancer patients.
Li, J., Haensch, W., Rudas, M., Kemmner, W., Warnick, P., Fischer, J., Gnant, M., Schlag, P.M. and Bembenek, A.
European Journal of Surgical Oncology 34 (8): 857-862. August 2008

REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis.
Astrosini, C., Roeefzaad, C., Dai, Y.Y., Dieckgraefe, B.K., Joens, T. and Kemmner, W.
International Journal of Cancer 123 (2): 409-413. 15 July 2008

„Der Onkologe“ jetzt zur Listung durch das Institute for Scientific Information (ISI) angenommen! ["The oncology" now accepted for listung through the Institute for Scientific Information (ISI)!].
Hoeffken, K., Bamberg, M. and Schlag, P.M.
Onkologe 14 (7): 657. July 2008

Construct validity testing of a laparoscopic surgery simulator (Lap Mentor((R))) : Evaluation of surgical skill with a virtual laparoscopic training simulator.
Zhang, A., Huenerbein, M., Dai, Y., Schlag, P.M. and Beller, S.
Surgical Endoscopy 22 (6): 1440-1444. June 2008

Markers of tumour angiogenesis and tumour cells in bone marrow in gastric cancer patients.
Gretschel, S., Astrosini, C.h., Vieth, M., Joens, T., Tomov, T., Hoecker, M., Schlag, P.M. and Kemmner, W.
European Journal of Surgical Oncology 34 (6): 642-647. June 2008

Portable biomedical devices: a critical issue during telecare services design.
Gortzis, L.G., Bakettas, I., Makropoulos, C., Graschew, G. and Nikiforidis, G.
Informatics for Health and Social Care 33 (2): 91-98. June 2008

Sentinel node biopsy in synovial sarcoma.
Tunn, P.U., Andreou, D., Illing, H., Fleige, B., Dresel, S. and Schlag, P.M.
European Journal of Surgical Oncology 34 (6): 704-707. June 2008

Improved tumour response by laser light treatment.
Graschew, G., Smith, J., Rakowsky, S., Roelofs, T.A., Schlag, P.M. and Stein, U.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE 6991 : 69911A. 2 May 2008

Alternative perspective on the rationale for lymphatic mapping for sentinel node identification in colon cancer.
Bembenek, A.E. and Schlag, P.M.
Annals of Surgery 247 (5): 904. May 2008

Can the presence of micrometastases in patients with colorectal cancer be used to help guide treatment?
Bembenek, A. and Schlag, P.M.
Nature Clinical Practice Gastroenterology & Hepatology 5 (5): 244-245. May 2008

Presence of mature DC-Lamp(+) dendritic cells in sentinel and non-sentinel lymph nodes of breast cancer patients.
Bembenek, A., Li, J., Loddenkemper, C., Kemmner, W., Stein, H., Wernecke, K.D. and Schlag, P.M.
European Journal of Surgical Oncology 34 (5): 514-518. May 2008

S3-guideline "exocrine pancreatic carcinoma" 2007 : Results of an Evidence-Based Consensus Conference (13. - 14.10.2006).
Adler, G., Seufferlein, T., Bischoff, S.C., Brambs, H.J., Feuerbach, S., Grabenbauer, G., Hahn, S., Heinemann, V., Hohenberger, W., Langrehr, J.M., Lutz, M.P., Micke, O., Neuhaus, H., Neuhaus, P., Oettle, H., Schlag, P.M., Schmid, R., Schmiegel, W., Schlottmann, K., Werner, J., Wiedenmann, B. and Kopp, I.
Zeitschrift fuer Gastroenterologie 46 (5): 449-482. May 2008

Development and validation of a three dimensional ultrasound based navigation system for tumor resection.
Chopra, S.S., Huenerbein, M., Eulenstein, S., Lange, T., Schlag, P.M. and Beller, S.
European Journal of Surgical Oncology 34 (4): 456-461. April 2008

Magenkarzinom – Behandlung im Umbruch [Gastric cancer - treatment in transformation].
Meyer, H.J. and Schlag, P.M.
Onkologe 14 (4): 327-328. April 2008

Response to Preoperative short-course radiotherapy in locally advanced rectal cancer: Value of F-fluorodeoxyglucose positron emission tomography.
Siegel, R., Dresel, S., Koswig, S., Gebauer, B., Huenerbein, M., Schneider, W. and Schlag, P.M.
Onkologie 31 (4): 166-172. April 2008

Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial.
Nordlinger, B., Sorbye, H., Glimelius, B., Poston, G.J., Schlag, P.M., Rougier, P., Bechstein, W.O., Primrose, J.N., Walpole, E.T., Finch-Jones, M., Jaeck, D., Mirza, D., Parks, R.W., Collette, L., Praet, M., Bethe, U., Van Cutsem, E., Scheithauer, W. and Gruenberger, T.
Lancet 371 (9617): 1007-1016. 22 March 2008

Feuerwehr – Feuermelder – Brandschutz. Auf die Reihenfolge kommt es an [Firefighters Fire alarm Fire protection. The right sequence is the key].
Hoeffken, K. and Schlag, P.M.
Onkologe 14 (2): 111-112. February 2008

Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer.
Kemmner, W., Wan, K., Ruttinger, S., Ebert, B., Macdonald, R., Klamm, U. and Moesta, K.T.
FASEB Journal 22 (2): 500-509. February 2008

Complete in vivo reversal of the multidrug resistance phenotype by jet-injection of anti-MDR1 short hairpin RNA-encoding plasmid DNA.
Stein, U., Walther, W., Stege, A., Kaszubiak, A., Fichtner, I. and Lage, H.
Molecular Therapy 16 (1): 178-186. January 2008

DELTASS - Disaster emergency logistic telemedicine advanced satellites system: Telemedical services for disaster emergencies.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Lieber, A., Muller, U., Czymek, R. and Dusel, W.
International Journal of Risk Assessment and Management 9 (4): 351-366. 2008

Design and implementation of satellite-based networks for global deployment of U-Health.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: 2nd Space Applications Symposium, SPACE APPLI 2008, 22-25 April 2008, Toulouse, France. 2008

Engineering for health in OP 2000.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
IFMBE Proceedings 22 : 871-874. 2008

From e-learning towards u-learning: ICT-enabled ubiquitous learning and training.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: 10th IASTED International Conference on Computers and Advanced Technology in Education, 8-10 Oct 2007, Beijing, China. 2008

Lokale nicht-virale Gentherapie in kutanen Metastasen von Mammakarzinom und Melanom: Ergebnisse einer Phase-I-Studie mittels Jet-Injektion nackter DNA.
Siegel, R., Kobelt, D., Knoesel, T., Stein, U., Schlag, P.M. and Walther, W.
Chirurgisches Forum 2008 37 : 131-132. 2008

Medical GRID and E-learning in the virtual hospital.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
IFMBE Proceedings 20 : 413-416. 2008

Network design for telemedicine - e-health using satellite technology.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
Studies in Health Technology and Informatics 131 : 67-82. 2008

PET in colorectal cancer.
Dresel, S. and Schlag, P.M.
Recent Results in Cancer Research 170 : 109-124. 2008

2007

Back to the future? Neue Aspekte in der Therapie der peritonealen Karzinose.
Schlag, P.M.
Chirurg 78 (12): 1083-1084. December 2007

Evaluation of higher-order time-domain perturbation theory of photon diffusion on breast-equivalent phantoms and optical mammograms.
Grosenick, D., Kummrow, A., Macdonald, R., Schlag, P.M. and Rinneberg, H.
Physical Review E 76 (6 Pt 1): 061908. December 2007

Exzessive Palliativchirurgie [Excessive palliative surgery].
Link, K.H. and Schlag, P.M.
Chirurgische Gastroenterologie 23 (4): 330-331. December 2007

Harnblasenkarzinom: Stetiger Behandlungsfortschritt als Antwort auf eine zunehmende Erkrankungsinzidenz [Carcinoma of the urinary bladder: steady progress in treatment as response to an increasing disease incidence].
Wirth, M. and Schlag, P.M.
Onkologe 13 (12): 1057. December 2007

Multiviszerale Resektion als Baustein eines multimodalen Behandlungskonzepts beim lokal fortgeschrittenen oder peritoneal metastasierten Magenkarzinom [Multivisceral resection as part of a multimodal treatment concept in locally progressed or peritoneally metastasized gastric cancer].
Gretschel, S. and Schlag, P.M.
Chirurgische Gastroenterologie 23 (4): 353-359. December 2007

Den Weg konsequent weitergehen [The path consequently continues].
Clement, J., Hoeffken, K. and Schlag, P.M.
Onkologe 13 (10): 893. October 2007

Sentinel lymph node biopsy for gastrointestinal cancers.
Bembenek, A., Gretschel, S. and Schlag, P.M.
Journal of Surgical Oncology 96 (4): 342-352. 15 September 2007

Collaborative work during interventional radiological procedures based on a multicast satellite-terrestrial network.
Gortzis, L.G., Papadopoulos, H., Roelofs, T.A., Rakowsky, S., Karnabatidis, D., Siablis, D., Makropoulos, C., Nikiforidis, G. and Graschew, G.
IEEE Transactions on Information Technology in Biomedicine 11 (5): 597-599. September 2007

[R1 resection in the region of the lower gastrointestinal tract: relevance and therapeutic consequences].
Huenerbein, M. and Schlag, P.M.
Chirurg 78 (9): 810-817. September 2007

Feasibility of navigated resection of liver tumors using multiplanar visualization of intraoperative 3-dimensional ultrasound data.
Beller, S., Huenerbein, M., Eulenstein, S., Lange, T. and Schlag, P.M.
Annals of Surgery 246 (2): 288-294. August 2007

Pankreaskarzinom: Kurzfassung der S3-Leitlinie 2007 [Carcinoma of the pancreas: summary of guidelines 2007, issued jointly by 15 German specialist medical societies].
Adler, G., Seufferlein, T., Bischoff, S.C., Brambs, H.J., Feuerbach, S., Grabenbauer, G., Hahn, S., Heinemann, V., Hohenberger, W., Langrehr, J.M., Lutz, M.P., Micke, O., Neuhaus, H., Neuhaus, P., Oettle, H., Schlag, P.M., Schmid, R., Schmiegel, W., Schlottmann, K., Werner, J., Wiedenmann, B. and Kopp, I.
Deutsche Medizinische Wochenschrift 132 (33): 1696-1700. August 2007

Efficacy of Different Technical Procedures for Sentinel Lymph Node Biopsy in Gastric Cancer Staging.
Gretschel, S., Bembenek, A., Huenerbein, M., Dresel, S., Schneider, W. and Schlag, P.M.
Annals of Surgical Oncology 14 (7): 2028-2035. July 2007

Image-guided surgery of liver metastases by three-dimensional ultrasound-based optoelectronic navigation.
Beller, S., Huenerbein, M., Lange, T., Eulenstein, S., Gebauer, B. and Schlag, P.M.
British Journal of Surgery 94 (7): 866-875. July 2007

Symptomorientierte Tumortherapie – eine interdisziplinaere Aufgabe [Symptom-oriented tumor therapy - an interdisciplinary task].
Feyer, P., Kloke, M. and Schlag, P.M.
Onkologe 13 (7): 575-576. July 2007

Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells.
Andre, S., Sanchez-Ruderisch, H., Nakagawa, H., Buchholz, M., Kopitz, J., Forberich, P., Kemmner, W., Boeck, C., Deguchi, K., Detjen, K.M., Wiedenmann, B., von Knebel Doeberitz, M., Gress, T.M., Nishimura, S., Rosewicz, S. and Gabius, H.J.
FEBS Journal 274 (13): 3233-3256. July 2007

Hepatic arterial Fotemustine chemotherapy in patients with liver metastases from cutaneous melanoma is as effective as in ocular melanoma.
Siegel, R., Hauschild, A., Kettelhack, C., Kaehler, K.C., Bembenek, A. and Schlag, P.M.
European Journal of Surgical Oncology 33 (5): 627-632. June 2007

Sentinel lymph node biopsy in colon cancer: A prospective multicenter trial.
Bembenek, A.E., Rosenberg, R., Wagler, E., Gretschel, S., Sendler, A., Siewert, J.R., Naehrig, J., Witzigmann, H., Hauss, J., Knorr, C., Dimmler, A., Groene, J., Buhr, H.J., Haier, J., Herbst, H., Tepel, J., Siphos, B., Kleespies, A., Koenigsrainer, A., Stoecklein, N.H., Horstmann, O., Gruetzmann, R., Imdahl, A., Svoboda, D., Wittekind, C., Schneider, W., Wernecke, K.D. and Schlag, P.M.
Annals of Surgery 245 (6): 858-863. June 2007

[S3-Guidelines "Exocrine pancreatic cancer" 2007.] S3-Leitlinie "Exokrines Pankreaskarzinom" 2007.
Adler, G., Seufferlein, T., Bischoff, S.C., Brambs, H.J., Feuerbach, S., Grabenbauer, G., Hahn, S., Heinemann, V., Hohenberger, W., Langrehr, J.M., Lutz, M.P., Neuhaus, H., Neuhaus, P., Oettle, H., Schlag, P.M., Schmid, R., Schmiegel, W., Schlottmann, K., Werner, J., Wiedenmann, B. and Kopp, I.
Zeitschrift fuer Gastroenterologie 45 : 487-523. June 2007

Authors' reply: Surgical strategies for gastric cancer with synchronous peritoneal carcinomatosis (Br J Surg 2006; 93: 1530-1535).
Schlag, P.M.
British Journal of Surgery 94 (5): 642-643. May 2007

Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway.
Wenzel, K., Daskalow, K., Herse, F., Seitz, S., Zacharias, U., Schenk, J.A., Schulz, H., Huebner, N., Micheel, B., Schlag, P.M., Osterziel, K.J., Ozcelik, C., Scherneck, S. and Jandrig, B.
Biological Chemistry 388 (5): 489-495. May 2007

Transkutane Sonographie.
Huenerbein, M., Chopra, S.S. and Schlag, P.M.
Chirurg 78 (5): 407-412. May 2007

Impact of patient- and disease-specific factors on SLNB in breast cancer patients. Are current guidelines justified?
Bembenek, A., Fischer, J., Albrecht, H., Kemnitz, E., Gretschel, S., Schneider, U., Dresel, S. and Schlag, P.M.
World Journal of Surgery 31 (2): 267-275. February 2007

Prognostic value of cytokeratin-positive bone marrow cells of gastric cancer patients.
Gretschel, S., Schick, C., Schneider, U., Estevez-Schwarz, L., Bembenek, A. and Schlag, P.M.
Annals of Surgical Oncology 14 : 373-380. February 2007

Resection of soft tissue sarcoma of the lower limb after evaluation of vascular invasion with intraoperative intravascular ultrasonography.
Huenerbein, M., Hohenberger, P., Stroszczynski, C., Bartelt, N., Schlag, P.M. and Tunn, P.U.
British Journal of Surgery 94 : 168-173. February 2007

Ductoscopic biopsy of papillary tumors in women with nipple discharge.
Huenerbein, M. and Schlag, P.M.
Annals of Surgery 245 (1): 154-155. January 2007

Heat-inducible in vivo gene therapy of colon carcinoma by human mdr1 promoter-regulated tumor necrosis factor-alpha expression.
Walther, W., Arlt, F., Fichtner, I., Aumann, J., Stein, U. and Schlag, P.M.
Molecular Cancer Therapeutics 6 (1): 236-243. January 2007

Targeted therapies - mehr als nur ein bahnbrechendes therapeutisches Prinzip.
Schlag, P.M.
Onkologe 13 (1): 7. January 2007

A new class of distance measures for registration of tubular models to image data.
Lange, T., Lamecker, H., Huenerbein, M., Eulenstein, S., Beller, S. and Schlag, P.M.
Informatik aktuell : 101-105. 2007

Clinical, biological, and molecular aspects of metastasis in colorectal cancer.
Stein, U. and Schlag, P.M.
Recent Results in Cancer Research 176 : 61-80. 2007

Design of networks for real-time tele-education.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: 6th IASTED International Conference on Web-Based Education, WBE 2007, 14-16 Mar 2007, Chamonix, France. 2007

Design of satellite-based networks for u-health - GALENOS, DELTASS, MEDASHIP, EMISPHER.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: 9th International Conference on e-Health Networking, Application and Services, 19-22 June 2007, Taipei, Taiwan. 2007

2006

Minimalresiduale Tumorerkrankung bei gastrointestinalen Karzinomen : Prognoserelevanz und onkologisch-chirurgische Konsequenzen [Minimal residual tumor in gastrointestinal carcinoma: Relevance to prognosis and oncologic surgical consequences].
Gretschel, S., Bembenek, A., Schulze, T., Kemmner, W. and Schlag, P.M.
Chirurg 77 (12): 1104-1117. 1 December 2006

Surgical strategies for gastric cancer with synchronous peritoneal carcinomatosis.
Gretschel, S., Siegel, R., Estevez-Schwarz, L., Huenerbein, M., Schneider, U. and Schlag, P.M.
British Journal of Surgery 93 (12): 1530-1535. December 2006

Das Modell der Adenom-Karzinom-Sequenz - ein Zwischenruf. Kommentar zu den Arbeiten von F. Stelzner.
Schlag, P.M.
Chirurg 77 (11): 1061-1062. November 2006

Magnetic resonance-guided biopsy of suspicious breast lesions with a handheld vacuum biopsy device.
Gebauer, B., Bostanjoglo, M., Moesta, K.T., Schneider, W., Schlag, P.M. and Felix, R.
Acta Radiologica 47 (9): 907-913. November 2006

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor (TCF) signaling in colon cancer.
Stein, U., Arlt, F., Walther, W., Smith, J., Waldman, T., Harris, E.D., Mertins, S.D., Heizmann, C.W., Allard, D., Birchmeier, W., Schlag, P.M. and Shoemaker, R.H.
Gastroenterology 131 (5): 1486-1500. November 2006

Bilaterales Fibulainterponat. Biologische Rekonstruktion nach Resektion primaer maligner Knochentumoren [Bilateral fibula graft. Biological reconstruction following resection of malignant bone tumors].
Tunn, P.U., Moesta, T.K. and Delbrueck, H.
Chirurg 77 : 919-925. October 2006

Ductoscopy and intraductal vacuum assisted biopsy in women with pathologic nipple discharge.
Huenerbein, M., Raubach, M., Gebauer, B., Schneider, W. and Schlag, P.M.
Breast Cancer Research and Treatment 99 (3): 301-307. October 2006

H-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signaling.
Nazarenko, I., Kristiansen, G., Fonfara, S., Guenther, R., Gieseler, C., Kemmner, W., Schaefer, R., Petersen, I. and Sers, C.
American Journal of Pathology 169 (4): 1427-1439. October 2006

Reversal of ABC transporter-dependent multidrug resistance in cancer: A realistic option?
Stein, U. and Walther, W.
American Journal of Cancer 5 (5): 285-297. September 2006

Correlation of visinin-like-protein-1 expression with clinicopathological features in squamous cell carcinoma of the esophagus.
Wickborn, C., Klein-Szanto, A.J., Schlag, P.M. and Braunewell, K.H.
Molecular Carcinogenesis 45 : 572-581. August 2006

Gastric cancer surgery in elderly patients.
Gretschel, S., Estevez-Schwarz, L., Huenerbein, M., Schneider, U. and Schlag, P.M.
World Journal of Surgery 30 : 1468-1474. August 2006

Abdomineller Vakuumsaugverband beim offenen Abdomen [Abdominal vacuum device with open abdomen].
Oetting, P., Rau, B. and Schlag, P.M.
Chirurg 77 (7): 586-593. July 2006

Uptake, biodistribution, and time course of naked plasmid DNA trafficking after intratumoral in vivo jet injection.
Walther, W., Minow, T., Martin, R., Fichtner, I., Schlag, P.M. and Stein, U.
Human Gene Therapy 17 (6): 611-624. 15 June 2006

Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression.
Pospisil, H., Herrmann, A., Butherus, K., Pirson, S., Reich, J.G. and Kemmner, W.
BMC Genomics 7 : 148. 13 June 2006

Digital medicine in the virtual hospital of the future.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
International Journal of Computer Assisted Radiology and Surgery 1 (Suppl 7) : 119-121. June 2006

Intraoperative ductoscopy in women undergoing surgery for breast cancer.
Huenerbein, M., Raubach, M., Gebauer, B., Schneider, W. and Schlag, P.M.
Surgery 139 : 833-838. June 2006

[Effect of cell surface sialic acid and their linkages on adhesion of mammary carcinoma cells].
Wang, X.Y., Lin, S.Q., Li, J.W., Kemmner, W. and Ding, Y.Q.
Journal of Southern Medical University 26 : 742-746. June 2006

Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy.
Sturm, I., Rau, B., Schlag, P.M., Wust, P., Hildebrandt, B., Riess, H., Hauptmann, S., Doerken, B. and Daniel, P.T.
BMC Cancer 6 : 124. 10 May 2006

Characterization of the recombinant adenovirus vector AdYB-1: implications for oncolytic vector development.
Glockzin, G., Mantwill, K., Juerchott, K., Bernshausen, A., Ladhoff, A., Royer, H.D., Gansbacher, B. and Holm, P.S.
Journal of Virology 80 : 3904-3911. 15 April 2006

Welchen Stellenwert hat die neoadjuvante und die adjuvante Therapie im Behandlungskonzept des Magenkarzinoms? [Efficacy of current adjuvant and neoadjuvant therapeutic concepts in gastric cancer?].
Kretzschmar, A. and Schlag, P.M.
Zentralblatt fuer Chirurgie 131 : 121-125. 13 April 2006

Hat die palliative Resektion bei gastrointestinalen Tumoren noch einen Stellenwert? [Significance of palliative resection of gastrointestinal tumors.].
Beller, S. and Schlag, P.M.
Chirurg 77 : 219-226. March 2006

Long-term morbidity of patients with early breast cancer after sentinel lymph node biopsy compared to axillary lymph node dissection.
Schulze, T., Mucke, J., Markwardt, J., Schlag, P.M. and Bembenek, A.
Journal of Surgical Oncology 93 : 109-119. 1 February 2006

Pre- and postoperative cytokine release after in vitro whole blood lipopolysaccharide stimulation and frequent toll-like receptor 4 polymorphisms.
Kumpf, O., Hamann, L., Schlag, P.M. and Schumann, R.R.
Shock 25 : 123-128. February 2006

Vascular endothelial growth factor-D and its receptor VEGFR-3: Two novel independent prognostic markers in gastric adenocarcinoma.
Juettner, S., Wissmann, C., Joens, T., Vieth, M., Hertel, J., Gretschel, S., Schlag, P.M., Kemmner, W. and Hoecker, M.
Journal of Clinical Oncology 24 (2): 228-240. 10 January 2006

"Multidrug-Resistenz". Zellulaere Transportprobleme und ihre Konsequenzen ["Multidrug resistance". Cellular transport problems and their consequences].
Stein, U., Walther, W. and Schlag, P.M.
Paediatrische Praxis 68 : 11-19. 1 January 2006

Laser microdissection of a colon cancer specimen with subsequent RNA isolation, mRNA amplification and microarray hybridization.
Stoinski-Bungs, E., Seeger, S., Kemmner, W., Scheinert, P. and Krupp, G.
Nature Methods Application Notes : an10-an11. 1 January 2006

Psychosozialer Betreuungsbedarf bei stationaeren Tumorpatienten. Untersuchungen an einer chirurgisch-onkologischen Schwerpunktklinik [Need for psychosocial care in in-patients with tumour disease. Investigations conducted in a clinic specializing in tumour surgery.].
Goerling, U., Odebrecht, S., Schiller, G. and Schlag, P.M.
Chirurg 77 : 41-46. January 2006

Cytokeratin profiles identify diagnostic signatures in colorectal cancer using multiplex analysis of tissue microarrays.
Knoesel, T., Emde, V., Schluens, K., Schlag, P.M., Dietel, M. and Petersen, I.
Cellular Oncology 28 : 167-175. 2006

Development of navigation systems for image-guided laparoscopic tumor resections in liver surgery.
Lange, T., Huenerbein, M., Eulenstein, S., Beller, S. and Schlag, P.M.
Recent Results in Cancer Research 167 : 13-36. 2006

Multidrug resistance.
Stein, U.
In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine ; Vol. 2. Springer, Berlin [u.a.], 1208-1212. ISBN 3-540-44244-8 2006

New trends in the virtualization of hospitals - tools for global e-Health.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Heinzlreiter, P., Kranzlmueller, D. and Volkert, J.
Studies in Health Technology and Informatics 121 : 168-175. 2006

Virtual hospital and digital medicine - Why is the GRID needed?
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Heinzlreiter, P., Kranzlmueller, D. and Volkert, J.
Studies in Health Technology and Informatics 120 : 295-304. 2006

2005

Telemedical applications and Grid technology.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Kaiser, S. and Albayrak, S.
In: Network Architectures, Management, and Applications III. Proceedings of SPIE ; 6022 . SPIE, Bellingham, Wash., 60220F (Article Number). ISBN 0-8194-6053-2 5 December 2005

Scanning time-domain optical mammography: detection and characterization of breast tumors in vivo.
Rinneberg, H., Grosenick, D., Moesta, K.T., Mucke, J., Gebauer, B., Stroszczynski, C., Wabnitz, H., Moeller, M., Wassermann, B. and Schlag, P.M.
Technology in Cancer Research & Treatment 4 (5): 483-496. 1 October 2005

Nonviral jet-injection gene transfer for efficient in vivo cytosine deaminase suicide gene therapy of colon carcinoma.
Walther, W., Stein, U., Fichtner, I., Kobelt, D., Aumann, J., Arlt, F. and Schlag, P.M.
Molecular Therapy 12 (6): 1176-1184. 29 September 2005

Registration of different phases of contrast-enhanced CT/MRI data for computer-assisted liver surgery planning: Evaluation of state-of-the-art methods.
Lange, T., Wenckebach, T.H., Lamecker, H., Seebass, M., Huenerbein, M., Eulenstein, S., Gebauer, B. and Schlag, P.M.
International Journal of Medical Robotics and Computer Assisted Surgery 1 : 6-20. 20 September 2005

Ex vivo sentinel lymph node study for rectal adenocarcinoma: Preliminary study - Invited commentary.
Schlag, P.M.
World Journal of Surgery 29 (9): 1171-1171. 25 August 2005

Needleless jet injection of naked DNA for nonviral in vivo gene transfer.
Walther, W. and Stein, U.
In: DNA-Pharmaceuticals: Formulation and Delivery in Gene Therapy, DNA Vaccination and Immunotherapy. Wiley-VCH, 133-143. ISBN 9783527311873 25 August 2005

Detection of lymph node micrometastases and isolated tumor cells in sentinel and nonsentinel lymph nodes of colon cancer patients.
Bembenek, A., Schneider, U., Gretschel, S., Fischer, J. and Schlag, P.M.
World Journal of Surgery 29 : 1172-1175. 11 August 2005

Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.
Gyoerffy, B., Serra, V., Juerchott, K., Abdul-Ghani, R., Garber, M., Stein, U., Petersen, I., Lage, H., Dietel, M. and Schaefer, R.
Oncogene 24 (15): 7542-7551. 25 July 2005

Kolon- und Rektumkarzinom [Tumors of the colon and rectum].
Link, K.H., Anthuber, M., Gastinger, I., Heitland, W., Metzger, U., Schnider, A., Schiedeck, T., Schlag, P.M. and Staib, L.
Chirurgische Gastroenterologie 21 : 177-182. 15 June 2005

Telemedicine in 20 years of CARS.
Graschew, G., Rakowsky, S., Roelofs, T.A. and Schlag, P.M.
International Congress Series 1281 : 175-179. 1 May 2005

"Multidrug-Resistenz". Zellulaere Transportprobleme und ihre Konsequenzen ["Multidrug resistance". Cellular transport problems and their consequences].
Stein, U., Walther, W. and Schlag, P.M.
Taegliche Praxis 46 (1): 125-133. 1 January 2005

CT-gesteuerte Resektion pulmonaler Metastasen [CT-guided resection of pulmonary metastases].
Gaffke, G., Stroszczynski, C., Rau, B., Liebeskind, U., Huenerbein, M., Bayraktar, S., Schlag, P.M. and Felix, R.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 177 : 877-883. 1 January 2005

Diagnostic work-up of rectal bleeding in general practice.
Heintze, C., Matysiak-Klose, D., Kroehn, T., Wolf, U., Brand, A., Meisner, C., Fischer, I., Wehrmeyer, H. and Braun, V.
British Journal of General Practice 55 (510): 14-19. 1 January 2005

In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms.
Wassermann, B., Kummrow, A., Moesta, K.T., Grosenick, D., Mucke, J., Wabnitz, H., Moeller, M., Macdonald, R., Schlag, P.M. and Rinneberg, H.
Optics Express 13 : 8571-8583. 1 January 2005

Limited surgery in early gastric cancer.
Gretschel, S. and Schlag, P.M.
Onkologie 28 : 243-244. 1 January 2005

Palliation of malignant rectal obstruction with self-expanding metal stents.
Huenerbein, M., Krause, M., Moesta, K.T., Rau, B. and Schlag, P.M.
Surgery 137 : 42-47. 1 January 2005

Prediction of gastric cancer lymph node status by sentinel lymph node biopsy and the Maruyama computer model.
Gretschel, S., Bembenek, A., Ulmer, C., Huenerbein, M., Markwardt, J., Schneider, U. and Schlag, P.M.
European Journal of Surgical Oncology 31 : 393-400. 1 January 2005

Quality of recombinant protein determines the amount of autoreactivity detected against the tumor-associated epithelial cell adhesion molecule antigen: low frequency of antibodies against the natural protein.
Schmetzer, O., Moldenhauer, G., Riesenberg, R., Pires, J.R., Schlag, P.M. and Pezzutto, A.
Journal of Immunology 174 (2): 942-952. 1 January 2005

Reconstruction of optical properties of phantom and breast lesion in vivo from paraxial scanning data.
Dierkes, T., Grosenick, D., Moesta, K.T., Moeller, M., Schlag, P.M., Rinneberg, H. and Arridge, S.
Physics in Medicine and Biology 50 : 2519-2542. 1 January 2005

Telemedical applications and Grid technology.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Albayrak, S. and Kaiser, S.
1 January 2005

Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients.
Grosenick, D., Moesta, K.T., Moeller, M., Mucke, J., Wabnitz, H., Gebauer, B., Stroszczynski, C., Wassermann, B., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 50 : 2429-2449. 1 January 2005

Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas.
Grosenick, D., Wabnitz, H., Moesta, K.T., Mucke, J., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 50 : 2451-2468. 1 January 2005

Use of the nuclease inhibitor aurintricarboxylic acid (ATA) for improved non-viral intratumoral in vivo gene transfer by jet-injection.
Walther, W., Stein, U., Siegel, R., Fichtner, I. and Schlag, P.M.
Journal of Gene Medicine 7 (4): 477-485. 1 January 2005

VEMH - Virtual Euro-Mediterranean Hospital for global healthcare.
Graschew, G., Roelofs, T.A., Rakowsky, S., Schlag, P.M., Kaiser, S. and Albayrak, S.
Studies in Health Technology and Informatics 114 : 39-45. 1 January 2005

YB-1 facilitates basal and 5-fluorouracil-inducible expression of the human major vault protein (MVP) gene.
Stein, U., Bergmann, S., Scheffer, G.L., Scheper, R.J., Royer, H.D., Schlag, P.M. and Walther, W.
Oncogene 24 (22): 3606-3618. 1 January 2005

Optimierung des Staging beim Kolonkarzinom durch Sentinel-Lymphknoten-Biopsie. Aktuelle Aspekte [Optimization of staging in colon cancer using sentinel lymph node biopsy].
Bembenek, A., Schneider, U., Gretschel, S., Ulmer, C. and Schlag, P.M.
Chirurg 76 (1): 58-67. January 2005

Der Weg zum diagnostischen "Tool" - Entwicklung eines Mikroarrays zur Prognose und Therapie-Praediktion von Darmkrebs [The pathway to diagnostic tool - Development of a microarray for the prognosis and therapy prediction of intestinal cancer].
Kloska, S., Eickhoff, H. and Kemmner, W.
Biospektrum 11 (1): 572-573. 2005

Molecular imaging of breast cancer in a transgene mouse model [Molekulare Bildgebung des Mammakarzinoms in einem transgenen Mausmodell].
Jakob, J., Perlitz, C., Ebert, B., Klamm, U., Kemmner, W., Haensch, W., Macdonald, R., Licha, K., Schirner, M., Schlag, P.M. and Moesta, K.T.
In: Chirurgisches Forum 2005 : fuer experimentelle und klinische Forschung 122. Kongress der Deutschen Gesellschaft fuer Chirurgie Berlin, 05.04.-08.04.2005. Deutsche Gesellschaft fuer Chirurgie, 34 . Springer, Berlin, 83-85. 2005

2004

Sentinel lymph node biopsy progress in surgical treatment of cancer.
Schulze, T., Bembenek, A. and Schlag, P.M.
Langenbecks Archives of Surgery 389 (6): 532-550. November 2004

ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.
Jandrig, B., Seitz, S., Hinzmann, B., Arnold, W., Micheel, B., Koelble, K., Siebert, R., Schwartz, A., Ruecker, K., Schlag, P.M., Scherneck, S. and Rosenthal, A.
Oncogene 23 (57): 9295-9302. 18 October 2004

Weichteilsakrome. Aktuelle multimodale Diagnostik als Basis einer differenzierten operativen Therapie [Soft tissue sarcoma. Differentiating surgery based on modern multidisciplinary diagnosis].
Tunn, P.U., Gebauer, B., Fritzmann, J., Huenerbein, M. and Schlag, P.M.
Chirurg 75 (12): 1165-1173. 11 September 2004

Sentinel node biopsy in gastrointestinal-tract cancer.
Schlag, P.M., Bembenek, A. and Schulze, T.
European Journal of Cancer 40 (14): 2022-2032. September 2004

A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signaling.
Hamann, L., Kumpf, O., Mueller, M., Visintin, A., Eckert, J., Schlag, P.M. and Schumann, R.R.
Genes and Immunity 5 (4): 283-288. 1 June 2004

Einfluss einer praeoperativen (hyperthermen) Radiochemotherapie auf die manometrisch erfasste Analsphinkterfunktion beim lokal fortgeschrittenen Rektumkarzinom [Influence of preoperative (hyperthermic) radiochemotherapy on manometric anal sphincter function in locally advanced rectal cancer].
Fritzmann, J., Huenerbein, M., Slisow, W., Gellermann, J., Wust, P. and Rau, B.
Strahlentherapie und Onkologie 180 : 281-288. 1 May 2004

Sentinel lymph node biopsy in rectal cancer - not yet ready for routine clinical use.
Bembenek, A., Rau, B., Moesta, T., Markwardt, J., Ulmer, C., Gretschel, S., Schneider, U., Slisow, W. and Schlag, P.M.
Surgery 135 (5): 498-505. May 2004

Impact of miniprobe ultrasonography on planning of minimally invasive surgery for gastric and colonic tumors.
Huenerbein, M., Handke, T., Ulmer, C. and Schlag, P.M.
Surgical Endoscopy 18 (4): 601-605. April 2004

Operative Interdisziplinaritaet und Telematik [Interdisciplinary surgery and telemedicine].
Schlag, P.M., Huenerbein, M., Ulmer, C. and Graschew, G.
Chirurg 75 (4): 411-417. April 2004

Concentration and oxygen saturation of haemoglobin of 50 breast tumours determined by time-domain optical mammography.
Grosenick, D., Wabnitz, H., Moesta, K.T., Mucke, J., Moeller, M., Stroszczynski, C., Stoessel, J., Wassermann, B., Schlag, P.M. and Rinneberg, H.
Physics in Medicine and Biology 49 (7): 1165-1181. 18 March 2004

Differences in the expression pattern of apoptosis-related molecules between childhood and adult de novo acute myeloid leukemia.
Wuchter, C., Richter, S., Oltersdorf, D., Karawajew, L., Ludwig, W.D. and Tamm, I.
Haematologica 89 : 363-364. 1 March 2004

Hans Gummel anlaesslich seines 30. Todesjahres. 1954-1973 Leitender Chirurg und Direktor der Robert-Roessle-Klinik [Hans Gummel on the 30th anniversary of his death. 1954-1973 chief surgeon and director of the Robert-Rossle Clinic].
Schlag, P.M.
Chirurg 75 (3): 300-301. 1 March 2004

Teilkoerperhyperthermie mit einem Radiofrequenz-Multiantennen-Applikator unter online Kontrolle in einem 1,5 T MR-Tomographen [Part-body hyperthermia with a radiofrequency multiantenna applicator under online control in a 1.5 T MR-tomograph].
Wust, P., Gellermann, J., Seebass, M., Faehling, H., Turner, P., Wlodarczyk, W., Nadobny, J., Rau, B., Hildebrandt, B., Oppelt, A., Schlag, P.M. and Felix, R.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 176 (3): 363-374. 1 March 2004

Refined staging by sentinel lymph node biopsy to individualize therapy in anal cancer.
Ulmer, C., Bembenek, A., Gretschel, S., Markwardt, J., Koswig, S., Schneider, U. and Schlag, P.M.
Annals of Surgical Oncology 11 (Supplement 3): 259S-262S. March 2004

New concepts of staging in gastrointestinal tumors as a basis of diagnosis and multimodal therapy.
Gretschel, S., Moesta, K.T., Huenerbein, M., Lange, T., Gebauer, B., Stroszczinski, C., Bembenek, A. and Schlag, P.M.
Onkologie 27 (1): 23-30. February 2004

Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage.
Cichon, G., Willnow, T.E., Herwig, S., Uckert, W., Loeser, P., Schmidt, H.H., Benhidjeb, T., Schlag, P.M., Schnieders, F., Niedzielska, D. and Heeren, J.
Journal of Gene Medicine 6 (2): 166-175. February 2004

Time for progress.
Adler, G. and Schlag, P.M.
Onkologie 27 (1): 11. February 2004

Bildgebende Diagnostik im praeoperativen Staging beim Rektumkarzinom [Imaging modalities in the preoperative staging of rectal carcinoma].
Hohenberger, P., Huenerbein, M., Gebauer, B. and Stroszczynski, C.
Chirurg 75 (1): 3-12. 1 January 2004

Chromosomal alterations during lymphatic and liver metastasis formation of colorectal cancer [Erratum in: Neoplasia. vol 6, pg 686, 2004].
Knoesel, T., Schluens, K., Stein, U., Schwabe, H., Schlag, P.M., Dietel, M. and Petersen, I.
Neoplasia 6 (1): 23-28. 1 January 2004

Imaging of colorectal adenocarcinoma using FT-IR microspectroscopy and cluster analysis.
Lasch, P., Haensch, W., Naumann, D. and Diem, M.
Biochimica et Biophysica Acta - Molecular Basis of Disease 1688 : 176-186. 1 January 2004

Low-volume jet injection for efficient nonviral in vivo gene transfer.
Walther, W., Stein, U., Fichtner, I. and Schlag, P.M.
Molecular Biotechnology 28 (2): 121-128. 1 January 2004

Osteosarcoma in children: long-term functional analysis.
Tunn, P.U., Schmidt-Peter, P., Pomraenke, D. and Hohenberger, P.
Clinical Orthopaedics and Related Research 421 : 212-217. 1 January 2004

Phantom phenomena in mastectomized patients and their relation to chronic and acute pre-mastectomy pain.
Rothemund, Y., Gruesser, S.M., Liebeskind, U., Schlag, P.M. and Flor, H.
Pain 107 (1-2): 140-146. 1 January 2004

Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology.
Amthauer, H., Denecke, T., Rau, B., Hildebrandt, B., Huenerbein, M., Ruf, J., Schneider, U., Gutberlet, M., Schlag, P.M., Felix, R. and Wust, P.
European Journal of Nuclear Medicine and Molecular Imaging 31 (6): 811-819. 1 January 2004

Reversal of P-glycoprotein mediated vincristine resistance of L1210/VCR cells by analogues of pentoxifylline - A QSAR study.
Kupsakova, I., Rybar, A., Docolomansky, P., Drobna, Z., Stein, U., Walther, W., Barancik, M. and Breier, A.
European Journal of Pharmaceutical Sciences 21 (2-3): 283-293. 1 January 2004

Sentinel Lymph Node beim kolorektalen Karzinom [Sentinel lymph node biopsy in colorectal carcinoma].
Bembenek, A., Gretschel, S., Ulmer, C. and Schlag, P.M.
Chirurg 75 (8): 761-766. 1 January 2004

Treatment of thoracic anastomotic leaks after esophagectomy with self-expanding plastic stents.
Huenerbein, M., Stroszczynski, C., Moesta, K.T. and Schlag, P.M.
Annals of Surgery 240 : 801-807. 1 January 2004

Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas.
Fichtner, I., Slisow, W., Gill, J., Becker, M., Elbe, B., Hillebrand, T. and Bibby, M.
European Journal of Cancer 40 (2): 298-307. January 2004

Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) gene expression via MEK/ERK-dependent activation of Sp1 and Sp3.
Strowski, M.Z., Cramer, T., Schaefer, G., Juettner, S., Walduck, A., Schipani, E., Kemmner, W., Wessler, S., Wunder, C., Weber, M., Meyer, T.F., Wiedenmann, B., Joens, T., Naumann, M. and Hoecker, M.
FASEB Journal 18 (1): 218-220. January 2004

Lebensqualitaet nach Rektumchirurgie [Quality of life after rectal surgery].
Hoppe de Mamani, S. and Schlag, P.M.
Chirurg 75 (1): 26-31. January 2004

Overexpression of cyclooxygenase-2 correlates with chromosomal gain at the cyclooxygenase-2 locus and decreased patient survival in advanced colorectal carcinomas.
Knosel, T., Yu, Y.W., Stein, U., Schwabe, H., Schluns, K., Schlag, P.M., Dietel, M. and Petersen, I.
Diseases of the Colon & Rectum 47 (1): 70-77. January 2004

2003

Prospective comparison of transcutaneous 3-dimensional US cholangiography, magnetic resonance cholangiography, and direct cholangiography in the evaluation of malignant biliary obstruction.
Huenerbein, M., Stroszczynski, C., Ulmer, C., Handke, T., Felix, R. and Schlag, P.M.
Gastrointestinal Endoscopy 58 (6): 853-858. December 2003

Ablative Verfahren bei der operativen Behandlung maligner Knochentumoren [Ablative procedures in surgical treatment of malignant bone tumors].
Tunn, P., Delbrueck, H. and Schlag, P.M.
Orthopaede 32 (11): 955-964. November 2003

Der Riesenzelltumor des Knochens : Eine Analyse von 87 Patienten [Giant cell tumor of bone. An evaluation of 87 patients].
Tunn, P.U. and Schlag, P.M.
Zeitschrift fuer Orthopaedie und Ihre Grenzgebiete 141 (6): 690-698. November 2003

Evaluation of pathologic nipple discharge with ductoscopy.
Huenerbein, M., Schwarz, L.E., Schneider, U. and Schlag, P.M.
Journal of the American College of Surgeons 197 (4): 697-698. October 2003

Genetic imbalances with impact on survival in colorectal cancer patients.
Knoesel, T., Schluens, K., Stein, U., Schwabe, H., Schlag, P.M., Dietel, M. and Petersen, I.
Histopathology 43 (4): 323-331. October 2003

Sentinel node biopsy in anal cancer - a promising strategy to individualize therapy.
Ulmer, C., Bembenek, A., Gretschel, S., Markwardt, J., Koswig, S., Slisow, W., Schneider, U. and Schlag, P.M.
Onkologie 26 (5): 456-460. October 2003

Dynamic expression profile of p21 WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy.
Rau, B., Sturm, I., Lage, H., Berger, S., Schneider, U., Haupfmann, S., Wust, P., Riess, H., Schlag, P.M., Doerken, B. and Daniel, P.T.
Journal of Clinical Oncology 21 (18): 3391-3401. 15 September 2003

Stability analysis for long-term storage of naked DNA: impact on nonviral in vivo gene transfer.
Walther, W., Stein, U., Voss, C., Schmidt, T., Schleef, M. and Schlag, P.M.
Analytical Biochemistry 318 (2): 230-235. 15 July 2003

Process for treating tumors with cytotoxic substances.
Stein, U., Walther, W. and Schlag, P.M.
US6,582,690. 24 June 2003

Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays.
Kemmner, W., Roefzaad, C., Haensch, W. and Schlag, P.M.
Biochimica et Biophysica Acta - General Subjects 1621 (3): 272-279. 11 June 2003

Time-domain optical mammography: initial clinical results on detection and characterization of breast tumors.
Grosenick, D., Moesta, K.T., Wabnitz, H., Mucke, J., Stroszczynski, C., Macdonald, R., Schlag, P.M. and Rinneberg, H.
Applied Optics 42 (16): 3170-3186. 1 June 2003

Pentoxifyllin attenuates the systemic inflammatory response induced during isolated limb perfusion with recombinant human tumor necrosis factor-α and melphalan.
Hohenberger, P., Latz, E., Kettelhack, C., Rezaei, A.H., Schumann, R. and Schlag, P.M.
Annals of Surgical Oncology 10 (5): 562-568. June 2003

Sentinel-Node-Biopsie : Definition, historische Entwicklung und methodisches Vorgehen.
Bembenek, A., Gretschel, S., Ulmer, C., Bayraktar, S. and Schlag, P.M.
Onkologe 9 (6): 599-610. June 2003

Telepresence over satellite.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: Cars 2003: Computer assisted radiology and surgery, proceedings. International congress series ; 1256, 1256 . Elsevier, Amsterdam, 273-278. ISBN 0531-5131 June 2003

Body mass index does not affect systematic D2 lymph node dissection and postoperative morbidity in gastric cancer patients.
Gretschel, S., Christoph, F., Bembenek, A., Estevez-Schwarz, L., Schneider, U. and Schlag, P.M.
Annals of Surgical Oncology 10 (4): 363-368. May 2003

Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.
Seitz, S., Wassmuth, P., Plaschke, J., Schackert, H.K., Karsten, U., Santibanez-Koref, M.F., Schlag, P.M. and Scherneck, S.
Genes Chromosomes & Cancer 37 (1): 29-35. May 2003

Outcome analysis of 189 consecutive cancer patients referred to the intensive care unit as emergencies during a 2-year period.
Maschmeyer, G., Bertschat, F.L., Moesta, K.T., Haeusler, E., Held, T.K., Nolte, M., Osterziel, K.J., Papstein, V., Peters, M., Reich, G., Schmutzler, M., Sezer, O., Stula, M., Wauer, H., Woertz, T., Wischnewsky, M. and Hohenberger, P.
European Journal of Cancer 39 : 783-792. 1 April 2003

Endosonography of upper gastrointestinal tract cancer on demand using miniprobes or endoscopic ultrasound.
Huenerbein, M., Ulmer, C., Handke, T. and Schlag, P.M.
Surgical Endoscopy 17 (4): 615-619. April 2003

Lipoplexes with alkylphospholipid as new helper lipid for efficient in vitro and in vivo gene transfer in tumor therapy.
Zeisig, R., Ress, A., Fichtner, I. and Walther, W.
Cancer Gene Therapy 10 (4): 302-311. April 2003

Synovialsarkome der Extremitaeten - Ergebnisse chirurgischer und multimodaler Therapie [Synovial sarcoma of the extremities. Results of surgical and multimodal therapy].
Ulmer, C., Kettelhack, C., Tunn, P.U., Reichardt, P., Hohenberger, P. and Schlag, P.M.
Chirurg 74 (4): 370-374. April 2003

Therapieverfahren fuer Adenokarzinome des oesophagogastralen Uebergangs [Treatment procedures for adenocarcinoma of the esophagogastric junction].
Moesta, K.T., Huenerbein, M. and Schlag, P.M.
Chirurg 74 (4): 381-393. April 2003

Traumareduktion durch minimal invasive Chirurgie : Gesicherte Daten und neue Strategien [Reducing trauma with minimally invasive surgery. Evidence and new strategies].
Huenerbein, M., Gretschel, S., Rau, B. and Schlag, P.M.
Chirurg 74 (4): 282-289. April 2003

Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1-and Sp3-dependent activation of two proximal GC-rich promoter elements.
Schaefer, G., Cramer, T., Suske, G., Kemmner, W., Wiedenmann, B. and Hoecker, M.
Journal of Biological Chemistry 278 (10): 8190-8198. 7 March 2003

Surgery, surgical education and surgical diagnostic procedures in the digital era.
Wysocki, W.M., Moesta, K.T. and Schlag, P.M.
Medical Science Monitor 9 (3): RA69-RA75. March 2003

Clinical use of the hyperthermia treatment planning system HyperPlan to predict effectiveness and toxicity.
Sreenivasa, G., Gellermann, J., Rau, B., Nadobny, J., Schlag, P.M., Deuflhard, P., Felix, R. and Wust, P.
International Journal of Radiation Oncology, Biology, Physics 55 (2): 407-419. 1 February 2003

Intrahepatic arterial versus intravenous fluorouracil and folinic acid for colorectal cancer liver metastases: a multicentre randomised trial.
Kerr, D.J., McArdle, C.S., Ledermann, J., Taylor, I., Sherlock, D.J., Schlag, P.M., Buckels, J., Mayer, D., Cain, D. and Stephens, R.J.
Lancet 361 (1): 368-373. 1 February 2003

Lymphatic mapping und Sentinel-Lymphknotendiagnostik beim Magenkarzinom [Lymphatic mapping and sentinel lymph node biopsy in gastric cancer].
Gretschel, S., Bembenek, A., Ulmer, C., Huenerbein, M., Markwardt, J., Schneider, U. and Schlag, P.M.
Chirurg 74 (2): 132-138. February 2003

Prognoserelevanz von biologischen und molekularen Markern in der Onkologie : Kriterien fur Studienplanung und -Interpretation. [Prognostic relevance of biological and molecular markers in oncology. Criteria for planning and interpreting studies].
Bollschweiler, E., Schneider, P.M., Moenig, S.P., Altendorf-Hofmann, A., Mansmann, U., Lehmacher, W., Schlag, P.M., Merkel, S., Hohenberger, W., Izbicki, J.R., Hermanek, P. and Hoelscher, A.H.
Chirurg 74 (2): 139-144. February 2003

Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors.
Wardelmann, E., Hrychyk, A., Merkelbach-Bruse, S., Pauls, K., Goldstein, J., Hohenberger, P., Losen, I., Manegold, C., Buettner, R. and Pietsch, T.
Journal of Molecular Diagnostics 6 : 197-204. 1 January 2003

Die Molekuele der Metastasierung [the molecules of metastasis].
Kemmner, W. and Schlag, P.M.
Chirurgische Praxis 61 : 203-212. 1 January 2003

Fluorimetrische Methoden in der chirurgischen Diagnostik.
Moesta, K.T., Ebert, B., Handke, T., Rinneberg, H. and Schlag, P.M.
In: Klinische Fluoreszenzdiagnostik und Photodynamische Therapie. Blackwell, Berlin [u.a.], 82-93. ISBN 3-89412-510-1 1 January 2003

Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR).
Fitze, G., Appelt, H., Koenig, I.R., Goergens, H., Stein, U., Walther, W., Gossen, M., Schreiber, M., Ziegler, A., Roesner, D. and Schackert, H.K.
Human Molecular Genetics 12 (24): 3207-3214. 1 January 2003

Gastric cancer.
Hohenberger, P. and Gretschel, S.
Lancet 362 : 305-315. 1 January 2003

Gastrointestinale Stromatumoren - Tumorentitaet und Therapie mit Imatinib.
Hohenberger, P., Reichardt, P., Stroszczynski, C., Schneider, U. and Hossfeld, D.K.
Deutsches Aerzteblatt 100 : 1334-1339. 1 January 2003

Isolated limb perfusion with rhTNF-alpha and melphalan for locally recurrent childhood synovial sarcoma of the limb.
Hohenberger, P. and Tunn, P.U.F.
Journal of Pediatric Hematology Oncology 25 : 905-909. 1 January 2003

Maligne Tumoren des Gastrointestinaltraktes.
Reichardt, P. and Schlag, P.M.
In: Harrisons Innere Medizin. ABW Wiss.-Verl., Berlin, 639-648. ISBN 3-936072-10-8 1 January 2003

Mammachirurgie.
Liebeskind, U. and Schlag, P.M.
In: Jahrbuch der Chirurgie. Biermann, Koeln, 175-196. ISBN 3-930-50542-8 1 January 2003

Metastasen bei unbekanntem Primaertumor.
Schlag, P.M. and Reichardt, P.
In: Harrisons Innere Medizin. ABW Wiss.-Verl., Berlin, 697-705. ISBN 3-936072-10-8 1 January 2003

Sarkome der Weichteile und des Knochens.
Schlag, P.M. and Reichardt, P.
In: Harrisons Innere Medizin. ABW Wiss.-Verl., Berlin, 692-696. ISBN 3-936072-10-8 1 January 2003

Sentinel-Lymphknoten-Biopsie bei Tumoren des Gastrointestinaltrakts.
Schlag, P.M., Bembenek, A., Bayraktar, S., Gretschel, S., Ulmer, C., Huenerbein, M. and Moesta, K.T.
Onkologe 9 (6): 625-631. 1 January 2003

Televideo-Tumorkonferenz: Schnittstelle fuer eine optimierte medizinische Versorgung und Dokumentation.
Suchy, B.R., Blanke, M., Ulmer, C. and Schlag, P.M.
Forum 18 : 12-14. 1 January 2003

Weichteiltumoren.
Tunn, P.U. and Schlag, P.M.
In: Lexikon orthopaedische Chirurgie : Standardterminologie fuer Orthopaeden und Unfallchirurgen. Springer, Berlin [u.a.], 231-233. ISBN 3-540-41317-0 1 January 2003

YB-1 as a cell cycle-regulated transcription factor facilitating cyclin A and cyclin B1 gene expression.
Juerchott, K., Bergmann, S., Stein, U., Walther, W., Janz, M., Manni, I., Piaggio, G., Fietze, E., Dietel, M. and Royer, H.D.
Journal of Biological Chemistry 278 (30): 27988-27996. 1 January 2003

Telemedizinische Visionen.
Feussner, H., Ricke, J., Hufnagl, P. and Schlag, P.M.
Onkologe 9 (1): 48-51. January 2003

Tumorkonferenz mittels multimedialer Videotelekommunikation.
Schlag, P.M., Ulmer, C. and Graschew, G.
Onkologe 9 (1): 13-22. January 2003

Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Gretschel, S., Haensch, W., Schlag, P.M. and Kemmner, W.
Oncology 65 (2): 139-145. 2003

2002

Modulation of steroid hormone uptake [Modulierung der Aufnahme von Steroidhormonen].
Willnow, T.E. and Nykjaer, A.
EP1419394 ; WO0299438. 16 December 2002

Verwendung des Nachweises der Expression von Splice-Varianten von Gen21 fuer die Diagnose und Therapie von Tumorerkrankungen [Use of the indication of the expression of splice variants of gene 21 for the diagnosis and treatment of tumour diseases].
Brett, D. and Kemmner, W.
DE10126472A1 ; WO0297119. 5 December 2002

Stellenwert der Hyperthermie fuer die chirurgische Onkologie.
Rau, B., Benhidjeb, T., Wust, P. and Schlag, P.M.
Viszeralchirurgie 37 (6): 379-384. December 2002

Mutation analysis and mRNA expression of trail-receptors in human breast cancer.
Seitz, S., Wassmuth, P., Fischer, J., Nothnagel, A., Jandrig, B., Schlag, P.M. and Scherneck, S.
International Journal of Cancer 102 (2): 117-128. 10 November 2002

Aspekte chirurgischer Therapie des kolorektalen Karzinoms.
Schlag, P.M.
Praxis : Schweizerische Rundschau fuer Medizin 91 (43): 1806-1810. 23 October 2002

Das Harnblasenkarzinom: interdisziplinaere Zusammenarbeit ist gefragt!
Dunst, J. and Schlag, P.M.
Onkologe 8 (9): 917. September 2002

Overexpression of c-erbB-2 protein correlates with chromosomal gain at the c-erbB-2 locus and patient survival in advanced colorectal carcinomas.
Knoesel, T., Yu, Y., Stein, U., Schwabe, H., Schluens, K., Schlag, P.M., Dietel, M. and Petersen, I.
Clinical and Experimental Metastasis 19 : 401-407. September 2002

Laser-induzierte Thermotherapie (LITT) bei malignen Lebertumoren: Einsatz der Sonographie zur Katheterplatzierung und Prozessbeobachtung [Laser-induced thermotherapy (LITT) for malignant liver tumours: the role of sonography in catheter placement and observation of the therapeutic procedure].
Stroszczynski, C., Gretschel, S., Gaffke, G., Puls, R., Kretzschmar, A., Hosten, N., Schlag, P.M. and Felix, R.
Ultraschall in der Medizin 23 (3): 163-167. 8 August 2002

Verwendung von EST-Sequenzen oder Varianten der Unigene-Cluster HS1, HS2 und/oder HS3 fuer die Diagnose und Therapie von Tumorerkrankungen sowie therapeutische Mittel.
Brett, D. and Kemmner, W.
DE10103694A1. 1 August 2002

Verwendung von Sialyltransferasen fuer die Diagnose und Therapie von Tumorerkrankungen [Use of sialyltransferases for diagnosing and treating tumorous diseases].
Schneider, F. and Kemmner, W.
DE10103695A1 ; WO0259350. 1 August 2002

Do we need surgical oncologists?
Schlag, P.M.
Onkologie 25 (4): 306-307. August 2002

Hyperthermia in combined treatment of cancer.
Wust, P., Hildebrandt, B., Sreenivasa, G., Rau, B., Gellermann, J., Riess, H., Felix, R. and Schlag, P.M.
Lancet Oncology 3 (8): 487-497. August 2002

Neue Diagnoseverfahren beim Mammakarzinom : Bedeutung fuer die operative Therapie.
Bembenek, A., Stroszczynski, C., Huenerbein, M., Markwardt, J. and Schlag, P.M.
Onkologe 8 (8): 817-825. August 2002

Sentinel lymphonodectomy in gastrointestinal cancer - where are we now?
Bembenek, A., Bayraktar, S., Gretschel, S., Ulmer, C., Schulze, T., Markwardt, J., Schneider, U., Huenerbein, M. and Schlag, P.M.
Onkologie 25 (4): 334-340. August 2002

Surgical oncology in the interplay of surgical and nonsurgical disciplines.
Schlag, P.M., Liebeskind, U., Bembenek, A., Slisow, W., Benhidjeb, T., Kettelhack, C. and Tunn, P.U.
Onkologie 25 (4): 309-316. August 2002

Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2.
Kowalski, P., Stein, U., Scheffer, G.L. and Lage, H.
Cancer Gene Therapy 9 (7): 579-586. July 2002

Vergleich von endorektaler MRT (EMRT) und endorektaler Sonographie (ES) nach operativer Therapie von Rektumkarzinomen zum Ausschluss von Rezidiven oder Residualtumoren [Comparison between endorectal MRI (EMRTI) and endorectal sonography (ES) after surgery or therapy for rectal tumors to exclude recurrent or residual tumor].
Pegios, W., Huenerbein, M., Schroeder, R., Wust, P., Schlag, P.M., Felix, R. and Vogl, T.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 174 (6): 731-737. 13 June 2002

Intratumoral low-volume jet-injection for efficient nonviral gene transfer.
Walther, W., Stein, U., Fichtner, I., Voss, C., Schmidt, T., Schleef, M., Nellessen, T. and Schlag, P.M.
Molecular Biotechnology 21 (2): 105-115. 1 June 2002

Verwendung des humanen LRP/MVP Promotors fuer einen Therapie-induzierbaren Vektor [Use of the human LRP/MVP promotor of a vector that can be induced by therapy].
Stein, U., Lange, C., Walther, W. and Schlag, P.M.
DE10055383A1 ; EP1332219 ; WO0238188. 29 May 2002

Cell surface α2,6-sialylation affects adhesion of breast carcinoma cells.
Lin, S.Q., Kemmner, W., Grigull, S. and Schlag, P.M.
Experimental Cell Research 276 (1): 101-110. 15 May 2002

Telemedizin: Optimierung von Tumorkonferenzen.
Sychy, B.R., Ulmer, C., Schlag, P.M., Rakowsky, S., Graschew, G., Weiser, H.F., Lange, V. and Buettner, C.
Deutsches Aerzteblatt 99 (19): A1278-A1280. 10 May 2002

Eine Tuer wird aufgestossen.
Schuette, J. and Schlag, P.M.
Onkologe 8 (4): 319. April 2002

Neue Entwicklungen der chirurgischen Therapie von Weichgewebssarkomen.
Hohenberger, P., Kettelhack, C., Tunn, P.U. and Schlag, P.M.
Onkologe 8 (4): 342-353. April 2002

Resection and local therapy for liver metastases.
Schlag, P.M., Benhidjeb, T. and Stroszczynski, C.
Best Practice & Research in Clinical Gastroenterology 16 (2): 299-317. April 2002

Verfahren zur Erfassung von Resistenz-Profilen von Geweben und Zellinien [Method of establishing resistance profiles of tissues and cell lines].
Stein, U. and Schlag, P.M.
DE10043591A1 ; EP1315838 ; WO0218630. 14 March 2002

Pentoxifylline influences drug transport activity of P-glycoprotein and decreases mdr1 gene expression in multidrug resistant mouse leukemic L1210/VCR cells.
Drobna, Z., Stein, U., Walther, W., Barancik, M. and Breier, A.
General Physiology and Biophysics 21 (1): 103-109. March 2002

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
Lustig, B., Jerchow, B., Sachs, M., Weiler, S., Pietsch, T., Karsten, U., van de Wetering, M., Clevers, H., Schlag, P.M., Birchmeier, W. and Behrens, J.
Molecular and Cellular Biology 22 (4): 1184-1193. 1 February 2002

Aspekte operativer Therapie gastrointestinaler Karzinome beim alten Patienten.
Schlag, P.M., Gretschel, S., Moesta, T., Ulmer, C., Benhidjeb, T. and Slisow, W.
Onkologe 8 (2): 167-172. February 2002

Incidence of chromosomal imbalances in advanced colorectal carcinomas and their metastases.
Knoesel, T., Petersen, S., Schwabe, H., Schluens, K., Stein, U., Schlag, P.M., Dietel, M. and Petersen, I.
Virchows Archiv 440 (2): 187-194. February 2002

Minimal access surgery for cancer treatment.
Schlag, P.M. and Huenerbein, M.
Onkologie 25 (1): 72-73. February 2002

T4-Rektumkarzinom : Operative und multimodale Therapie [T4 rectal cancer. Surgery and multimodal therapy].
Rau, B., Hohenberger, P., Gellermann, J., Huenerbein, M., Hildebrandt, B., Schneider, U., Riess, H., Wust, P. and Schlag, P.M.
Chirurg 73 (2): 147-153. February 2002

Three-dimensional ultrasound cholangiography: a new noninvasive technique for evaluation of biliary obstruction (Comment on: Am J Gastroenterol. 2001 Jul;96(7):1959-60, Am J Gastroenterol. 2001 Jul;96(7):2074-80).
Huenerbein, M., Stroszczynski, C., Felix, R. and Schlag, P.M.
American Journal of Gastroenterology 97 (2): 500-501. February 2002

31phosphorus-magnetic resonance spectroscopy to assess histologic tumor response noninvasively after isolated limb perfusion for soft tissue tumors.
Kettelhack, C., Wickede, M.V., Vogl, T., Schneider, U. and Hohenberger, P.
Cancer 94 : 1557-1564. 1 January 2002

Aneurysma der Vena poplitea als Ursache rezidivierender Lungenarterienembolien mit Reanimationspflichtigkeit.
Schupfner, B., Osterziel, K. and Hohenberger, P.
Deutsche Medizinische Wochenschrift 127 (24): 1312-1316. 1 January 2002

Applications of Broadband Optical and Wireless Networks : 16 - 17 Oktober 2002, Shanghai, China.
Graschew, G and Schlag, PM, eds.
SPIE Proceedings Series ; 4912 . SPIE, Bellingham, Wash.. ISBN 0-8194-4701-3 1 January 2002

Besonderheiten chirurgischer Eingriffe bei Patienten mit Leukaemien.
Hohenberger, P. and Schlichting, C.L.
Onkologe 8 : 729-736. 1 January 2002

Chirurgie der Lungenmetastasen extrapulmonaler Primaertumore.
Rau, B., Roth, C., Schnider, A. and Metzger, U.
Schweizerisches Medizin-Forum 49 : 1166-1170. 1 January 2002

Diagnostik von Duenndarmtumoren mit Hilfe des CT-Enteroklysma. Die CT--Sellink ausgewertet bei 63 Patienten [Diagnosis of tumors of the small intestine with the aid of CT contrast enema. Sellink CT technique evaluated in 63 patients].
Gaffke, G., Stroszczynski, C., Schlecht, I., Jost, D., Ludwig, W.D., Schlag, P.M. and Felix, R.
Roentgenpraxis 54 (6): 214-219. 1 January 2002

Einfluss einer praeoperativen hyperthermen Radiochemotherapie auf die Sphinkterfunktion.
Fritzmann, J., Slisow, W., Wust, P. and Rau, B.
In: Digitale Revolution in der Chirurgie : 119. Kongress der Deutschen Gesellschaft fuer Chirurgie, 7. - 10. Mai 2002, Berlin. Springer, Berlin [u.a.], 438-439. ISBN 3-540-44330-4 1 January 2002

Expression of multidrug resistance genes MVP, MDR1 and MRP1 determined longitudinally prior to, during, and post hyperthermic isolated limb perfusion for soft tissue sarcoma and melanoma patients.
Stein, U., Juerchott, K., Schlaefke, M. and Hohenberger, P.
Proceedings of the American Association of Cancer Research 43 : 272. 1 January 2002

Expression of multidrug resistance genes MVP, MDR1, and MRP1 determined sequentially before, during, and after hyperthermic isolated limb perfusion of soft tissue sarcoma and melanoma patients.
Stein, U., Juerchott, K., Schlafke, M. and Hohenberger, P.
Journal of Clinical Oncology 20 (15): 3282-3292. 1 January 2002

Impact of BCRP/MXR, MRP1 and MDR1/P-glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer.
Stein, U., Lage, H., Jordan, A., Walther, W., Bates, S.E., Litman, T., Hohenberger, P. and Dietel, M.
International Journal of Cancer 97 (6): 751-760. 1 January 2002

Interactive videocommunication networks over satellite in the operating room of the future - OP 2000.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: Telemedicine in care delivery: technology and application. National Institute of Health, Rome, 49-54. 1 January 2002

Knochentumoren.
Schlag, P.M., Schmidt-Peter, P. and Tunn, P.U.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 546-569. ISBN 3-13-126111-0 1 January 2002

Maligne Hauttumoren.
Schlag, P.M. and Kettelhack, C.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 494-521. ISBN 3-13-126111-0 1 January 2002

Maligne Tumoren des Duenndarms.
Schlag, P.M. and Benhidjeb, T.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 389-398. ISBN 3-13-126111-0 1 January 2002

Molekulare Reaktionsformen und bildgebende Diagnostik gastro-intestinaler Stromatumoren auf die Therapie mit Tyrosinkinase Inhibitor Imatinib (STI571).
Hohenberger, P., Schneider, U., Reichardt, P., Pink, D. and Stroszczynski, C.
In: Chirurgisches Forum 2002 fuer experimentelle und klinische Forschung. Springer, Berlin [u.a.], 117-120. ISBN 3-540-43300-7 1 January 2002

Oesophageal cancer.
Benhidjeb, T. and Hohenberger, P.
In: Oxford textbook of oncology, Vol. 2. Oxford Univ. Press, Oxford [u.a.], 1483-1616. ISBN 0-19-262926-3 1 January 2002

Oxford Textbook of Oncology.
Souhami, R.L., Tannock, I., Hohenberger, P. and Horiot, J.C.
Oxford Univ. Press, Oxford [u.a.]. ISBN 0-19-262926-3 1 January 2002

Paradigmenwechsel in der Therapie gastrointestinaler Stromatumoren.
Reichardt, P., Pink, D. and Hohenberger, P.
Onkologe 8 : 378-383. 1 January 2002

Pathophysiological aspects of the pneumoperitoneum.
Hohenberger, P.
In: Staging laparoscopy. Springer, Berlin [u.a.], 27-39. ISBN 3-540-65632-4 1 January 2002

Principles of surgical oncology.
Hohenberger, P.
In: Oxford textbook of oncology, Vol. 1. Oxford Univ. Press, Oxford [u.a.], 347-364. ISBN 0-19-262926-3 1 January 2002

Prinzipien der chirurgischen Tumortherapie.
Junginger, T. and Schlag, P.M.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 25-32. ISBN 3-13-126111-0 1 January 2002

Psychotherapeutische und psychoonkologische Betreuung von Patienten mit Sarkomen.
Hermann, A., Rosenbaum, M., Hoppe, V. and Hohenberger, P.
Onkologe 8 : 366-377. 1 January 2002

Quantification of optical properties of a breast tumor using random walk theory.
Chernomordik, V., Hattery, D.W., Grosenick, D., Wabnitz, H., Rinneberg, H., Moesta, K.T., Schlag, P.M. and Gandjbakhche, A.
Journal of Biomedical Optics 7 (1): 80-87. 1 January 2002

Restaging of locally advanced carcinoma of the rectum with MR imaging after preoperative radio-chemotherapy plus regional hyperthermia.
Hoffmann, K.T., Rau, B., Wust, P., Stroszczynski, C., Huenerbein, M., Schneider, U. and Felix, R.
Strahlentherapie und Onkologie 7 : 386-392. 1 January 2002

Satellite - based networks for interactive telemedicine.
Graschew, G., Roelofs, T., Rakowsky, S. and Schlag, P.M.
In: IFMBE Proceedings. Verlag der Technischen Universitaet, Graz, 1393-1394. 1 January 2002

Sentinel Lymphknoten-Biopsie am Beispiel Mammachirurgie.
Bembenek, A. and Schlag, P.M.
In: Jahrbuch der Chirurgie. Biermann, Koeln, 35-50. ISBN 3-930505-38-X 1 January 2002

Staging laparoscopy.
Hohenberger, P. and Conlon, K.C.
Springer, Berlin [u.a.]. ISBN 3-540-65632-4 1 January 2002

Staging laparoscopy for esophageal cancer.
Rau, B., Huenerbein, M., Hohenberger, P. and Schlag, P.M.
In: Staging laparoscopy. Springer, Berlin [u.a.], 55-67. ISBN 3-540-65632-4 1 January 2002

Tumoren der Brustdruese.
Schlag, P.M., Liebeskind, U. and Bembenek, A.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 96-141. ISBN 3-13-126111-0 1 January 2002

Tumorgenese.
Schlag, P.M., Estevez-Schwarz, L., Kemmner, W., Schumacher, K. and Walther, W.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 2-17. ISBN 3-13-126111-0 1 January 2002

Tumorschmerztherapie.
Schlag, P.M., Kumpf, O. and Papstein, V.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 52-79. ISBN 3-13-126111-0 1 January 2002

Use of the human MDR1 promoter for heat-inducible expression of therapeutic genes.
Walther, W., Stein, U. and Schlag, P.M.
International Journal of Cancer 98 (2): 291-296. 1 January 2002

Weichgewebssarkome.
Schlag, P.M. and Kettelhack, C.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 521-545. ISBN 3-13-126111-0 1 January 2002

Characterization of colorectal adenocarcinoma sections by spatially resolved FT-IR microspectroscopy.
Lasch, P., Haensch, W., Lewis, E.N., Kidder, L.H. and Naumann, D.
Applied Spectroscopy 56 (1): 1-9. January 2002

Krebsregister - Motor fuer Verbesserungen in der Onkologie.
Michaelis, J. and Schlag, P.M.
Onkologe 8 (1): 13. January 2002

Mammakarzinom bei maennlichen Patienten.
Estevez-Schwarz, L. and Schlag, P.M.
Onkologe 8 (1): 66-71. January 2002

Aspekte chirurgischer Therapie des kolorektalen Karzinoms.
Schlag, P.M.
In: IX. Gastroenterologie Seminarwoche Titisee 2002. Falk Foundation, Freiburg, 171-174. 2002

Axillaere Dissektion versus Sentinel-Lymphknotenbiopsie-biopsie - nicht konkurrierende, sondern ergaenzende Verfahren in der Therapie des Mammakarzinoms.
Bembenek, A., Liebeskind, A.U. and Schlag, P.M.
Viszeralchirurgie 37 (2): 127-130. 2002

Broadband networks for interactive telemedical applications.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: Applications of Broadband Optical and Wireless Networks : 16 - 17 October 2002, Shanghai, China. SPIE Proceedings Series ; 4912, 4912 . SPIE, Bellingham, Wash., 1-6. ISBN 0-8194-4701-3 2002

Bronchoskopie unter Spontanatmung im perioperativen Management pulmonaler Komplikationen.
Moesta, K.T., Ulmer, C., Kumpf, O., Rau, B. and Schlag, P.M.
Viszeralchirurgie 37 (3): 237-742. 2002

Chirurgische Aspekte in der Therapie des Oesophaguskarzinoms.
Benhidjeb, T., Lehr, C.T. and Schlag, P.M.
Geriatrie Journal 4 : 41-43. 2002

Diagnostik von Duenndarmtumoren mit Hilfe des CT-Entreoklysma : Die CT - Sellink ausgewertet bei 63 Patienten.
Gaffke, G., Stroszczynski, C., Schlecht, I., Jost, D., Ludwig, W.D., Schlag, P.M. and Felix, R.
Roentgenpraxis 54 (6): 214-219. 2002

Differenzialtherapie von Lungenmetastasen extrapulmonaler solider Tumoren.
Rau, B., Huenerbein, M. and Schlag, P.M.
Chirurgische Praxis 60 (2): 203-218. 2002

Einsatz der Laser-induzierten Thermotherapie zur Thermoablation von Osteoidosteomen.
Schupfner, B., Tunn, P.U., Stroszczynski, C. and Schlag, P.M.
In: Digitale Revolution in der Chirurgie : 119. Kongress der Deutschen Gesellschaft fuer Chirurgie, 7. - 10. Mai 2002, Berlin. Deutsche Gesellschaft für Chirurgie, 2002 . Springer, Berlin [u.a], 722-722. ISBN 3-540-44330-4 2002

Erfahrungen mit der Hyperthermen Radiochemotherapie (HRCT) beim Plattenepithelkarzinom des Oesophagus: Ergebnisse einer prospektiven Studie.
Benhidjeb, T., Huenerbein, M., Koswig, S., Moesta, T., Budach, V. and Schlag, P.M.
In: Digitale Revolution in der Chirurgie : 119. Kongress der Deutschen Gesellschaft fuer Chirurgie, 7. - 10. Mai 2002, Berlin. Springer, Berlin [u.a.], 344-344. ISBN 978-3-540-44330-8 2002

Interactive telemedical applications in OP 2000 via satellite.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
Biomedizinische Technik 47 (S1 Pt 1): 330-333. 2002

Is there additional information from laparoscopic ultrasound in tumor staging?
Rau, B., Huenerbein, M. and Schlag, P.M.
Digestive Surgery 19 (6): 479-483. 2002

Kolorektales Karzinom.
Liebeskind, U., Slisow, W., Schlag, P.M., Roedel, C., Sauer, R., Koehne, C.H. and Grothey, A.
In: Geriatrische Onkologie. Springer, Berlin [u.a.], 607-633. ISBN 3-540-67411-X 2002

Laparoscopic ultrasonography for staging of gastrointestinal cancer.
Huenerbein, M., Rau, B., Hohenberger, P. and Schlag, P.M.
In: Staging laparoscopy. Springer, Berlin [u.a.], 113-124. ISBN 3-540-65632-4 2002

Lokale Tumorkontrolle nach operativer und multimodaler Therapie von Weichgewebsarkomen im Extremitaetenbereich.
Kettelhack, C., Aqua, J., Hohenberger, W. and Schlag, P.M.
In: Digitale Revolution in der Chirurgie : 119. Kongress der Deutschen Gesellschaft fuer Chirurgie, 7. - 10. Mai 2002, Berlin. Springer, Berlin [u.a.], 447-447. ISBN 3-540-44330-4 2002

OP-2000 - Erprobung von telemedizinischen Netzwerken.
Graschew, G., Roelofs, T., Rakowsky, S. and Schlag, P.M.
In: Telemedizinfuehrer Deutschland. Dtsch.Med.Forum, Bad Nauheim, 234-237. ISBN 3-00-008519-X 2002

Resektionsausmass und Indikation zur multimodalen Therapie bei lokoregionaer fortgeschrittenen Tumoren des kleinen Beckens.
Hohenberger, P., Althaus, P., Coswig, S., Slisow, W., Rau, B. and Schlag, P.M.
In: Digitale Revolution in der Chirurgie : 119. Kongress der Deutschen Gesellschaft fuer Chirurgie, 7. - 10. Mai 2002, Berlin. Springer, Berlin [u.a.], 443-444. ISBN 3-540-44330-4 2002

Sentinel lymph node biopsy (SLNB) in GI-tract cancer.
Schlag, P.M., Bembenek, A., Gretschel, S. and Rau, B.
Tumori 1 : S22-S23. 2002

Strategien zur Gentherapie von Tumorerkrankungen [Gene therapy strategies for tumor diseases].
Walther, W., Stein, U. and Schlag, P.M.
Chirurgische Praxis 60 : 19-26. 2002

WinVicos - Vavelet-based interactive video communication system for medical and non-medial applications.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: Productivity Reincarnation Through Robotics & Automation : IEEE ICIT '02, 2002 IEEE International Conference on Industrial Technology ; 11 - 14 December 2002, Shangri-La Hotel, Bangkok, Thailand. 2002 IEEE International Conference on Industrial Technology, 2 . IEEE Operations Center, Piscataway, NJ, 864-868. ISBN 0-7803-7657-9 2002

2001

Hemangiosarcoma of the bone. Problems arising from the heterogeneity of malignant vascular tumors of the bone.
Krause, M., Tunn, P.U. and Schneider, U.
Onkologie 24 : 486-489. 1 October 2001

Radiologisch-interventionelle Leberportanlage: Evaluierung, Zugangswege, Intervention und Nachkontrolle.
Puls, R., Stroszczynski, C., Hildebrandt, B., Amthauer, H., Podrabsky, P., Hidajat, N., Riess, H., Schlag, P.M. and Hosten, N.
RoeFo Fortschritte auf dem Gebiete der Roentgenstrahlen und der neuen bildgebenden Verfahren 173 : 914-919. 1 October 2001

Tumorprofiling durch Microarray-Technologie [Tumor-profiling by microarray technology].
Lustig, B., Morkel, M. and Schlag, P.M.
Onkologe 7 (10): 1111-1119. October 2001

Einfluss der Positronenemissionstomographie auf die chirurgische Therapieplanung beim colorectalen Rezidivtumor [Influence of positron emission tomography on surgical therapy planning in recurrent colorectal cancer].
Schlag, P.M., Amthauer, H., Stroszczynski, C. and Felix, R.
Chirurg 72 (9): 995-1002. September 2001

Regression of high-grade gastric B-cell lymphoma after eradication of Helicobacter pylori.
Gretschel, S., Huenerbein, M., Foss, H.D., Krause, M. and Schlag, P.M.
Endoscopy 33 (9): 805-807. September 2001

Zum Stellenwert der laparoskopischen Sonographie fuer das Staging gastrointestinaler Tumoren [The role of laparoscopic ultrasound for staging of gastrointestinal tumors].
Huenerbein, M., Rau, B., Hohenberger, P. and Schlag, P.M.
Chirurg 72 (8): 914-919. August 2001

A rapid bioinformatic method identifies novel genes with direct clinical relevance to colon cancer.
Brett, D., Kemmner, W., Koch, G., Roefzaad, C., Gross, S. and Schlag, P.M.
Oncogene 20 (33): 4581-4585. 27 July 2001

Histopathological correlation to MRI findings during and after laser-induced thermotherapy in a pig pancreas model.
Stroszczynski, C., Hosten, N., Puls, R., Nagel, S., Scholman, H.J., Wlodarczyk, W., Oettle, H., Moesta, K.T., Schlag, P.M. and Felix, R.
Investigative Radiology 36 (7): 413-421. 1 July 2001

Lymphatic mapping and retrieval of the sentinel lymph node in treatment of early breast cancer.
Bembenek, A., Markwardt, J. and Schlag, P.M.
European Radiology 11 (7): 1191-1194. July 2001

Overexpression of sialyltransferase CMP-sialic Acid : Galbeta1,3GalNAc-R alpha6-sialyltransferase is related to poor patient survival in human colorectal carcinomas.
Schneider, F., Kemmner, W., Haensch, W., Franke, G., Gretschel, S., Karsten, U. and Schlag, P.M.
Cancer Research 61 (11): 4605-4611. 1 June 2001

Multiphoton versus single photon excitation of photosensitizers for laser-induced fluorescence diagnosis and photodynamic therapy of cancer cells.
Roelofs, T.A., Graschew, G., Schneider, M., Rakowsky, S., Sinn, H.J. and Schlag, P.M.
In: Multiphoton Microscopy in the Biomedical Sciences : 21 - 23 January 2001, San Jose, USA. SPIE Proceedings Series ; 4262, 4262 . SPIE, Bellingham, Wash., 259-262. ISBN 0-8194-3940-1 24 April 2001

Radiochemotherapie plus Hyperthermie beim Rektumkarzinom.
Rau, B., Wust, P., Riess, H. and Schlag, P.M.
Schweizerische Rundschau fuer Medizin Praxis 90 (14): 587-592. 5 April 2001

Temperature data and specific absorption rates in pelvic tumours: predictive factors and correlations.
Tilly, W., Wust, P., Rau, B., Harder, C., Gellermann, J., Schlag, P.M., Budach, V. and Felix, R.
International Journal of Hyperthermia 17 : 172-188. 1 March 2001

Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas.
Wiechen, K., Sers, C., Agoulnik, A., Arlt, K., Dietel, M., Schlag, P.M. and Schneider, U.
American Journal of Pathology 158 (3): 833-839. March 2001

Minimal-invasive Chirurgie. Aspekte der chirurgischen Onkologie des Gastrointestinaltrakts [Minimal invasive surgery. Aspects of surgical oncology of the gastrointestinal tract].
Schlag, P.M., Rau, B., Schnider, A. and Huenerbein, M.
Chirurg 72 (3): 245-251. March 2001

Staging und neoadjuvante Therapie des Plattenepithelkarzinoms des Oesophagus [Staging and neoadjuvant therapy for esophageal cancer].
Benhidjeb, T., Moesta, K.T. and Schlag, P.M.
Therapeutische Umschau 58 (3): 165-173. March 2001

Assessment of quality of life in cancer patients: complexity, criticism, challenges.
Grumann, M. and Schlag, P.M.
Onkologie 24 (1): 10-15. February 2001

Comparison of quality of life in patients undergoing abdominoperineal extirpation or anterior resection for rectal cancer.
Grumann, M.M., Noack, E.M., Hoffmann, I.A. and Schlag, P.M.
Annals of Surgery 233 (2): 149-156. February 2001

The role of transrectal ultrasound-guided biopsy in the postoperative follow-up of patients with rectal cancer.
Huenerbein, M., Totkas, S., Moesta, K.T., Ulmer, C., Handke, T. and Schlag, P.M.
Surgery 129 (2): 164-169. February 2001

Therapeutische Strategien bei malignen Weichteiltumoren : Ergebnisse der Weichteiltumor-Registerstudie der CAO.
Junginger, T., Kettelhack, C., Schoenfelder, M., Saeger, H.D., Rieske, H., Krummenauer, F. and Hermanek, P.
Chirurg 72 (2): 138-148. February 2001

Early responses of human cancer cells upon photodynamic treatment monitoring by laser phase microscopy.
Roelofs, T.A., Graschew, G., Perevedentseva, E.V., Rakowsky, S., Dressler, C., Beuthan, J. and Schlag, P.M.
In: Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy X : 20 - 21 January 2001, San Jose, USA. SPIE Proceedings Series ; 4248, 4248 . SPIE, Bellingham, Wash., 163-168. ISBN 0-8194-3926-6 20 January 2001

Checkliste Onkologie.
Senn, H.J., Drings, P., Glaus, A., Jungi, W.F., Pralle, H.B., Sauer, R. and Schlag, P.M.
Thieme, Stuttgart [u.a.]. ISBN 3-13-685504-3 1 January 2001

Chirurgische Onkologie.
Schackert, H.K., Schlag, P.M. and Huenerbein, M.
In: Chirurgie. Urban & Fischer, Muenchen [u.a.], 297-310. ISBN 3-437-41926-9 1 January 2001

Colorectal cancer - what is standard surgery?
Hohenberger, P.
European Journal of Cancer 37 (S7) : 173-187. 1 January 2001

Constitutional genomic instability with inversions, duplications, and amplifications in 9p23-24 in BRCA2 mutation carriers.
Savelyeva, L., Claas, A., Matzner, I., Schlag, P.M., Hofmann, W., Scherneck, S., Weber, B. and Schwab, M.
Cancer Research 61 : 5179-5185. 1 January 2001

Der kommunikative Umgang mit dem Thema "Zukunft" bei Krebspatienten : Dargestellt am Beispiel von Patienten mit Sarkomen waehrend der stationaeren chirurgischen Behandlung.
Hermann, A., Zaumseil, M. and Hohenberger, P.
Onkologe 7 : 167-177. 1 January 2001

Detailed deletion mapping in sporadic breast cancer at chromosomal region 17p13 distal to the TP53 gene: association with clinicopathological parameters.
Seitz, S., Poppe, K., Fischer, J., Nothnagel, A., Estevez-Schwarz, L., Haensch, W., Schlag, P.M. and Scherneck, S.
Journal of Pathology 194 (3): 318-326. 1 January 2001

Die Sentinel-Node-Biopsie beim malignen Melanom.
Kettelhack, C. and Schlag, P.M.
In: Sentinel Lymphknoten Biopsie. ecomed, Landsberg, 87-100. ISBN 3-609-16009-8 1 January 2001

Evaluierung von Ergebnissen der Sentinel-Lymphknoten-Biopsie.
Bembenek, A. and Pichlmeier, U.
In: Sentinel Lymphknoten Biopsie. ecomed, Landsberg, 199-202. ISBN 3-609-16009-8 1 January 2001

GALENOS as interactive telemedical network via satellite.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: Optical network design and management : 13 - 15 November 2001, Beijing, China. SPIE Proceedings Series ; 4584, 4584 . SPIE, Bellingham, Wash., 202-205. ISBN 0-8194-4314-X 1 January 2001

Hyperthermia-induced nuclear translocation of transcription factor YB-1 leads to enhanced expression of multidrug resistance-related ABC transporters.
Stein, U., Juerchott, K., Walther, W., Bergmann, S., Schlag, P.M. and Royer, H.D.
Journal of Biological Chemistry 276 (30): 28562-28569. 1 January 2001

In vivo Gentransfer nackter DNA in xenotransplantierte Kolonkarzinome in der Nude Maus mit Hilfe der Jet-Injektion [In vivo gene transfer of naked DNA into xenotransplanted colon carcinoma by jet-injection].
Walther, W., Stein, U., Fichtner, I. and Schlag, P.M.
Chirurgisches Forum 30 : 69-72. 1 January 2001

Interactive medical teleteaching and teletraining in the GALENOS satellite networktelecommunications for education and training.
Graschew, G., Roelofs, T.A., Rakowsky, S. and Schlag, P.M.
In: Proceeding. Charles Univ., Prague, 70-72. 1 January 2001

Konzept und Entwicklung des Lymphatic Mapping und der Sentinel-Node-Biopsie.
Liebeskind, U. and Schlag, P.M.
In: Sentinel Lymphknoten Biopsie. ecomed, Landsberg, 11-18. ISBN 3-609-16009-8 1 January 2001

Near-infrared fluorescent dyes for enhanced contrast in optical mammography: phantom experiments.
Ebert, B., Sukowski, U., Grosenick, D., Wabnitz, H., Moesta, T.K., Licha, K., Becker, A., Semmler, W., Schlag, P.M. and Rinneberg, H.
Journal of Biomedical Optics 6 : 134-140. 1 January 2001

Nonviral in vivo gene delivery into tumors using a novel low volume jet-injection technology.
Walther, W., Stein, U., Fichtner, I., Malcherek, L., Lemm, M. and Schlag, P.M.
Gene Therapy 8 (3): 173-180. 1 January 2001

Operative Therapie des primaeren und metastasierten Melanoms.
Breuninger, H. and Kettelhack, C.
Onkologe 7 : 36-43. 1 January 2001

Pathohistologische Aspekte der Sentinel-Lymphknoten-Biopsie.
Schneider, U.
In: Sentinel Lymphknoten Biopsie. ecomed, Landsberg, 69-86. ISBN 3-609-16009-8 1 January 2001

Perceptual phenomena after unilateral arm amputation: a pre-post-surgical comparison.
Gruesser, S.M., Winter, C., Schaefer, M., Fritzsche, K., Benhidjeb, T., Tunn, P.U., Schlag, P.M. and Flor, H.
Neuroscience Letters 302 (1): 13-16. 1 January 2001

Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas.
Schumacher, K., Haensch, W., Roefzaad, C. and Schlag, P.M.
Cancer Research 61 : 3932-3936. 1 January 2001

Protoporphyrin IX occurs naturally in colorectal cancers and their metastases.
Moesta, K.T., Ebert, B., Handke, T., Nolte, D., Nowak, C., Haensch, W.E., Pandey, R.K., Dougherty, T.J., Rinneberg, H. and Schlag, P.M.
Cancer Research 61 : 991-999. 1 January 2001

Rekonstruktive Gefaesschirurgie im Rahmen erweiterter Tumorchirurgie.
Hohenberger, P.
In: Gefaesschirurgie. Urban & Fischer, Muenchen [u.a.], 538-550. ISBN 3-437-21840-9 1 January 2001

Sentinel Lymphknoten Biopsie.
Schlag, P.M.
ecomed, Landsberg. ISBN 3-609-16009-8 1 January 2001

Sentinel node detection.
Bembenek, A. and Schlag, P.M.
In: Surgical treatment - evidence-based and problem-oriented. Zuckschwerdt, Muenchen [u.a.], 591-596. ISBN 3-88603-714-2 1 January 2001

Sentinel-Lmphknoten-Diagnostik - Kolorektales Karzinom und Analkarzinom.
Bembenek, A., Ulmer, C. and Schlag, P.M.
In: Sentinel Lymphknoten Biopsie. ecomed, Landsberg, 191-198. ISBN 3-609-16009-8 1 January 2001

Sentinel-Lymphknoten-Biopsie beim Magenkarzinom.
Gretschel, S. and Schlag, P.M.
In: Sentinel Lymphknoten Biopsie. ecomed, Landsberg, 175-190. ISBN 3-609-16009-8 1 January 2001

Sentinel-Lymphonodektomie - Erfahrungen beim Mammakarzinom.
Bembenek, A. and Schlag, P.M.
In: Sentinel Lymphknoten Biopsy. ecomed, Landsberg, 101-118. 1 January 2001

Sentinel-Node-Biopsie beim Magenkarzinom.
Gretschel, S. and Schlag, P.M.
In: Sentinel Lymphknoten Biopsie. ecomed, Landsberg, 175-190. ISBN 3-609-16009-8 1 January 2001

Technik der Sentinel-Lymphonodektomie.
Gretschel, S. and Markwardt, J.
In: Sentinel Lymphknoten Biopsie. ecomed, Landsberg, 35-48. ISBN 3-609-16009-8 1 January 2001

Weichteilsarkome.
Hohenberger, P., Reichardt, P. and Pink, D.
In: Jahrbuch der Chirurgie. Biermann, Koeln, 213-226. ISBN 3-930-50535-5 1 January 2001

Wolf in sheep's clothing: spilled gallstones can cause severe complications after endoscopic surgery : Case report and review of literature.
Gretschel, S., Engelmann, C., Estevez-Schwarz, L. and Schlag, P.M.
Surgical Endoscopy 15 (1): 98. January 2001

"Umdenken" heisst interdisziplinaer denken.
Schlag, P.M.
Onkologe 7 (4): 361. 2001

Bildgebende Diagnostik des Rektumkarzinoms : Moderne Verfahren und zukuenftige Entwicklung.
Stroszczynski, C., Huenerbein, M., Felix, R. and Schlag, P.M.
Onkologe 7 (4): 370-380. 2001

Chirurgische Behandlung des Rektumkarzinoms im hohen Alter.
Slisow, W. and Schlag, P.M.
Geriatrie Journal 3 (1-2): 35-39. 2001

Continuing medical education (CME) in Der Onkologe.
Schlag, P.M. and Roessling, W.
Onkologe 7 (4): 420. 2001

Fluorescence diagnostics.
Schlag, P.M. and Moesta, K.T.
In: Encyclopedic reference of cancer. Springer, Berlin [u.a.], 338-340. ISBN 3-540-66527-7 2001

Kein Grund zur Rast.
Hoelscher, A.H. and Schlag, P.M.
Onkologe 7 (6): 601-602. 2001

Laser diagnostics.
Moesta, K.T. and Schlag, P.M.
In: Encyclopedic reference of cancer. Springer, Berlin [u.a.], 490-491. ISBN 3-540-66527-7 2001

Lymphknotendissektion unter Beruecksichtigung des Sentinel Lymphknoten (SN) Exstirpationsverfahrens.
Liebeskind, U., Bembenek, A., Gretschel, S. and Schlag, P.M.
In: Panta rhei - Umdenken - Umdenken. Langenbeck's Archive, Kongressband, 118 . Springer, Berlin [u.a.], 915-916. ISBN 978-3-540-42694-3 2001

Multimodale Therapiekonzepte beim Oesophaguskarzinom.
Schlag, P.M. and Benhidjeb, T.
Viszeralchirurgie 36 (1): 6-11. 2001

Nutzen ohne zu schaden - Auf der Suche nach hoeherer Effizienz.
Tilgen, W. and Schlag, P.M.
Onkologe 7 (1): 12-13. 2001

Operative und multimodale Therapieverfahren in Kombination mit Hyperthermie bei Weichgewebssarkomen.
Schlag, P.M.
MedReview 2 (9): 26-27. 2001

Optical mammography.
Moesta, K.T. and Schlag, P.
In: Encyclopedic reference of cancer. Springer, Berlin [u.a.], 652-653. ISBN 3-540-66527-7 2001

Prinzipien der regionalen Hyperthermie in Kombination mit Strahlentherapie und Chemotherapie.
Wust, P., Rau, B. and Schlag, P.M.
In: Onkologische Chirurgie. Praxis der Viszeralchirurgie . Springer, Berlin [u.a.], 227-239. ISBN 3-540-65963-3 2001

Prognosefaktoren beim Magenkarzinom.
Gretschel, S., Kemmner, W. and Schlag, P.M.
Onkologe 7 (6): 623-631. 2001

Sentinel lymph node biopsy in breast cancer.
Bembenek, A., Liebeskind, U. and Schlag, P.M.
In: The Sentinel lymph node concept in oncology. Facts and fiction . Zuckschwerdt, Muenchen, 98-111. ISBN 3-88603-739-8 2001

Staging Laparoskopie mit laparoskopischer Ultraschallanwendung - Indikation und Stellenwert im chirurgisch-onkologischen Therapiekonzept [Staging laparoscopy with laparoscopic ultrasound - indications and value in the surgical oncological therapy concept].
Hohenberger, P., Rau, B., Huenerbein, M. and Schlag, P.M.
Zeitschrift fuer Gastroenterologie 39 (Supplement 1): 29-34. 2001

Tumormetastasierung.
Ghadimi, B.M. and Schlag, P.M.
In: Onkologische Chirurgie. Praxis der Viszeralchirurgie . Springer, Berlin [u.a.], 77-85. ISBN 3-540-65963-3 2001

Weichgewebsarkome - Epidemiologie, chirurgische Diagnostik und Therapie.
Kettelhack, C. and Schlag, P.M.
In: Onkologische Chirurgie. Praxis der Viszeralchirurgie . Springer, Berlin [u.a.], 773-796. ISBN 3-540-65963-3 2001

2000

Cloning and initial analysis of the human multidrug resistance-related MVP/LRP gene promoter.
Lange, C., Walther, W., Schwabe, H. and Stein, U.
Biochemical and Biophysical Research Communications 278 (1): 125-133. 11 November 2000

Prospective comparison of endorectal ultrasound, three-dimensional endorectal ultrasound, and endorectal MRI in the preoperative evaluation of rectal tumors. Preliminary results.
Huenerbein, M., Pegios, W., Rau, B., Vogl, T.J., Felix, R. and Schlag, P.M.
Surgical Endoscopy 14 (11): 1005-1009. November 2000

Bedeutung der Wartezeit bei Tumorpatienten am Beispiel der Vorbehandlung des lokal fortgeschrittenen Rektumkarzinom.
Gretschel, S., Rau, B., Wust, P., Riess, H. and Schlag, P.M.
Strahlentherapie und Onkologie 176 (10): 448-451. 1 October 2000

Preoperative radiochemotherapy in locally advanced or recurrent rectal cancer: regional radiofrequency hyperthermia correlates with clinical parameters.
Rau, B., Wust, P., Tilly, W., Gellermann, J., Harder, C., Riess, H., Budach, V., Felix, R. and Schlag, P.M.
International Journal of Radiation Oncology, Biology, Physics 48 (2): 381-391. 6 September 2000

Auto gegen Pferd - zur Schnellschnitt-Diagnostik per Telepathologie.
Dietel, M., Dierks, C., Hufnagl, P. and Schlag, P.M.
Pathologe 21 (5): 391-393. 1 September 2000

BRCA1 and BRCA2 - breast cancer susceptibility genes.
Hofmann, W. and Schlag, P.M.
Journal of Cancer Research and Clinical Oncology 126 (9): 487-496. 1 September 2000

Regional hyperthermia for rectal cancer.
Hildebrandt, B., Wust, P., Rau, B., Schlag, P.M. and Riess, H.
Lancet 356 (9231): 771-772. 26 August 2000

Cholangiocellular carcinoma associated with segmental Caroli's disease.
Totkas, S. and Hohenberger, P.
European Journal of Surgical Oncology 26 : 520-521. 1 August 2000

Die besondere Herausforderung des seltenen Tumors: Chirurgische und multimodale Therapie des Pseudomyxoma peritonei.
Totkas, S., Schneider, U. and Schlag, P.M.
Chirurg 71 : 869-876. 1 August 2000

Refined deletion mapping in sporadic breast cancer at chromosomal region 8p12-p21 and association with clinicopathological parameters.
Seitz, S., Werner, S., Fischer, J., Nothnagel, A., Schlag, P.M. and Scherneck, S.
European Journal of Cancer 36 (12): 1507-1513. 1 August 2000

In vivo gene transfer by low-volume jet injection.
Cartier, R., Ren, S.V., Walther, W., Stein, U., Lewis, A., Schlag, P.M., Li, M. and Furth, P.A.
Analytical Biochemistry 282 (2): 262-265. 1 July 2000

Preoperative evaluation of colorectal neoplasms by colonoscopic miniprobe ultrasonography.
Huenerbein, M., Totkas, S., Ghadimi, B.M. and Schlag, P.M.
Annals of Surgery 232 : 46-50. 1 July 2000

Lymph-node dissection in breast cancer.
Bembenek, A. and Schlag, P.M.
Langenbecks Archives of Surgery 385 (4): 236-245. July 2000

Mittel zum nichtviralen Transfer von DNS in eukaryotische Zellen.
Zeisig, R. and Walther, W.
DE19959690A1. 8 June 2000

Postoperative follow-up for colorectal cancer - What is left?
Schlag, P.M., Liebeskind, U. and Gutz, H.J.
Onkologie 23 : 202-206. 1 June 2000

mdr1 promoter-driven tumor necrosis factor-alpha expression for a chemotherapy-controllable combined in vivo gene therapy and chemotherapy of tumors.
Walther, W., Stein, U., Fichtner, I., Alexander, M., Shoemaker, R.H. and Schlag, P.M.
Cancer Gene Therapy 7 (6): 893-900. 1 June 2000

Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1.
Janke, J., Schlueter, K., Jandrig, B., Theile, M., Koelble, K., Arnold, W., Grinstein, E., Schwartz, A., Estevez-Schwarz, L., Schlag, P.M., Jockusch, B.M. and Scherneck, S.
Journal of Experimental Medicine 191 (10): 1675-1685. 15 May 2000

Sequential trimetrexate, 5-fluorouracil and folinic acid are effective and well tolerated in metastatic colorectal carcinoma. The phase II study group of the AIO.
Szelenyi, H., Hohenberger, P., Lochs, H., Haboubi, N., Berdel, W.E., Thiel, E. and Kreuser, E.D.
Oncology 58 : 273-279. 1 May 2000

Induction of systemic serum procalcitonin and cardiocirculatory reactions after isolated limb perfusion with recombinant human tumor necrosis factor-alpha and melphalan.
Kettelhack, C., Hohenberger, P., Schulze, G., Kilpert, B. and Schlag, P.M.
Critical Care Medicine 28 : 1040-1046. 1 April 2000

Multiphoton excitation and photodynamic activity of macromolecular derivatizated mTHPC.
Schneider, M., Graschew, G., Roelofs, T., Balanos, E., Rakowsky, S., Sinn, H. and Schlag, P.M.
In: Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IX. SPIE Procceedings Series ; 3909, 3909 . SPIE, Bellingham (U.S.A.), 60-65. ISBN 0-8194-3525-2 29 March 2000

Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Petretti, T., Kemmner, W., Schulze, B. and Schlag, P.M.
Gut 46 (3): 359-366. March 2000

High-copy cDNA amplification of minimal total RNA quantities for gene expression analyses.
Schwabe, H., Stein, U. and Walther, W.
Molecular Biotechnology 14 (2): 165-172. 1 February 2000

Immunohistochemical detection of lymph-node metastases.
Bembenek, A., Haensch, W., Schneider, U., Markwardt, J. and Schlag, P.M.
Lancet 355 : 144-145. 8 January 2000

Three-dimensional ultrasonography: new prospects for ultrasound imaging of bone.
Huenerbein, M., Raschke, M., Haas, N.P. and Schlag, P.M.
Lancet 355 (9198): 116-117. 8 January 2000

"Sentinel" Lymphknotenbiopsie beim Mammakarzinom: Aktulle Erfahrungencancer. Recent experiences.
Bembenek, A., Kettelhack, C., Reuhl, T., Markwardt, J., Hohenberger, P., Schneider, U. and Schlag, P.M.
Zentralblatt fuer Chirurgie 125 (10): 817-821. 1 January 2000

Chemotherapy-inducible vector for gene therapy of cancer.
Walther, W., Stein, U., Shoemaker, R.H. and Schlag, P.M.
In: Gene Therapy of Cancer : Methods and Protocols ; 35. Methods in Molecular Medicine ; 35 . Humana Press, Totowa, 371-392. 1 January 2000